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Search of human proteins with 148664211
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|148664211 immunoglobulin superfamily, member 4D isoform 2
[Homo sapiens]
(414 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Ho... 827 0.0
gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Ho... 812 0.0
gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens] 312 4e-85
gi|21686977 cell adhesion molecule 4 [Homo sapiens] 296 2e-80
gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens] 280 1e-75
gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens] 274 9e-74
gi|11386199 poliovirus receptor-related 3 [Homo sapiens] 103 2e-22
gi|51593098 class-I MHC-restricted T cell associated molecule [H... 94 2e-19
gi|222136611 poliovirus receptor-related 4 [Homo sapiens] 91 1e-18
gi|209413732 poliovirus receptor isoform delta [Homo sapiens] 91 2e-18
gi|209413726 poliovirus receptor isoform alpha [Homo sapiens] 91 2e-18
gi|112789532 poliovirus receptor related 2 isoform delta precurs... 89 1e-17
gi|5360210 poliovirus receptor related 2 isoform alpha precursor... 87 2e-17
gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens] 84 2e-16
gi|209413728 poliovirus receptor isoform beta [Homo sapiens] 84 3e-16
gi|209413730 poliovirus receptor isoform gamma [Homo sapiens] 83 4e-16
gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens] 81 2e-15
gi|110349719 titin isoform N2-A [Homo sapiens] 80 3e-15
gi|221316762 neurotrimin isoform 4 [Homo sapiens] 79 8e-15
gi|221316757 neurotrimin isoform 3 [Homo sapiens] 79 8e-15
gi|7705413 neurotrimin isoform 1 [Homo sapiens] 79 8e-15
gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens] 77 3e-14
gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapi... 76 5e-14
gi|115298665 neurotrimin isoform 2 [Homo sapiens] 75 8e-14
gi|4505505 opioid binding protein/cell adhesion molecule-like is... 74 2e-13
gi|45594240 limbic system-associated membrane protein [Homo sapi... 74 2e-13
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 74 3e-13
gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens] 73 4e-13
gi|157819143 IgLON family member 5 [Homo sapiens] 73 5e-13
gi|166295173 kin of IRRE like [Homo sapiens] 72 1e-12
>gi|148664211 immunoglobulin superfamily, member 4D isoform 2 [Homo
sapiens]
Length = 414
Score = 827 bits (2137), Expect = 0.0
Identities = 414/414 (100%), Positives = 414/414 (100%)
Query: 1 MASVVLPSGSQCAAAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVA 60
MASVVLPSGSQCAAAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVA
Sbjct: 1 MASVVLPSGSQCAAAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVA 60
Query: 61 TISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEG 120
TISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEG
Sbjct: 61 TISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEG 120
Query: 121 RYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWF 180
RYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWF
Sbjct: 121 RYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWF 180
Query: 181 KGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQ 240
KGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQ
Sbjct: 181 KGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQ 240
Query: 241 YKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFI 300
YKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFI
Sbjct: 241 YKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFI 300
Query: 301 NNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDSRAGEEGSIRAVDHAVIGGVVAVVVFAM 360
NNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDSRAGEEGSIRAVDHAVIGGVVAVVVFAM
Sbjct: 301 NNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDSRAGEEGSIRAVDHAVIGGVVAVVVFAM 360
Query: 361 LCLLIILGRYFARHKGTYFTHEAKGADDAADADTAIINAEGGQNNSEEKKEYFI 414
LCLLIILGRYFARHKGTYFTHEAKGADDAADADTAIINAEGGQNNSEEKKEYFI
Sbjct: 361 LCLLIILGRYFARHKGTYFTHEAKGADDAADADTAIINAEGGQNNSEEKKEYFI 414
>gi|148664190 immunoglobulin superfamily, member 4D isoform 1 [Homo
sapiens]
Length = 442
Score = 812 bits (2098), Expect = 0.0
Identities = 414/442 (93%), Positives = 414/442 (93%), Gaps = 28/442 (6%)
Query: 1 MASVVLPSGSQCAAAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVA 60
MASVVLPSGSQCAAAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVA
Sbjct: 1 MASVVLPSGSQCAAAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVA 60
Query: 61 TISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEG 120
TISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEG
Sbjct: 61 TISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEG 120
Query: 121 RYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWF 180
RYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWF
Sbjct: 121 RYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWF 180
Query: 181 KGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQ 240
KGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQ
Sbjct: 181 KGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQ 240
Query: 241 YKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFI 300
YKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFI
Sbjct: 241 YKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFI 300
Query: 301 NNLNKTDNGTYRCEASNIVGKAHSDYMLYVY----------------------------D 332
NNLNKTDNGTYRCEASNIVGKAHSDYMLYVY D
Sbjct: 301 NNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDPPTTIPPPTTTTTTTTTTTTTILTIITD 360
Query: 333 SRAGEEGSIRAVDHAVIGGVVAVVVFAMLCLLIILGRYFARHKGTYFTHEAKGADDAADA 392
SRAGEEGSIRAVDHAVIGGVVAVVVFAMLCLLIILGRYFARHKGTYFTHEAKGADDAADA
Sbjct: 361 SRAGEEGSIRAVDHAVIGGVVAVVVFAMLCLLIILGRYFARHKGTYFTHEAKGADDAADA 420
Query: 393 DTAIINAEGGQNNSEEKKEYFI 414
DTAIINAEGGQNNSEEKKEYFI
Sbjct: 421 DTAIINAEGGQNNSEEKKEYFI 442
>gi|54607031 immunoglobulin superfamily, member 4D [Homo sapiens]
Length = 437
Score = 312 bits (799), Expect = 4e-85
Identities = 178/415 (42%), Positives = 247/415 (59%), Gaps = 47/415 (11%)
Query: 44 GQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFS 103
GQ T++VTV+EG A ++C+V+++D++ +Q NP +QT+YF D + L+D+R +L+ S
Sbjct: 26 GQFPLTQNVTVVEGGTAILTCRVDQNDNTSLQWSNPAQQTLYFDDKKALRDNRIELVRAS 85
Query: 104 SSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIE 163
EL +S+++VS+SDEG+Y C L+T P + S +TVL P I +EG+ ++
Sbjct: 86 WHELSISVSDVSLSDEGQYTCSLFTMPVKTSKAYLTVLGVPEKPQISGFSSPVMEGDLMQ 145
Query: 164 VNCTAMASKPATTIRWFKGNTELKGKSEVEEWS---DMYTVTSQLMLKVHKEDDGVPVIC 220
+ C SKPA IRWFK + E+K ++E +TV+S L +V + DDGV VIC
Sbjct: 146 LTCKTSGSKPAADIRWFKNDKEIKDVKYLKEEDANRKTFTVSSTLDFRVDRSDDGVAVIC 205
Query: 221 QVEHPAVTGNLQ-TQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVT 279
+V+H ++ Q + LE+ Y P V I P +EG L LTCE+ GKP P V
Sbjct: 206 RVDHESLNATPQVAMQVLEIHYTPSVKI---IPSTPFPQEGQPLILTCESKGKPLPEPVL 262
Query: 280 WVRVDDEM--PQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYD----- 332
W + E+ P V+SG L I LNKTDNGTYRCEA+N +G++ ++Y+L V+D
Sbjct: 263 WTKDGGELPDPDRMVVSGRELNILFLNKTDNGTYRCEATNTIGQSSAEYVLIVHDVPNTL 322
Query: 333 ------------------------SRAGEEGSIR---------AVDHAVIGGVVAVVVFA 359
+ + SIR DHA+IGG+VAVVVF
Sbjct: 323 LPTTIIPSLTTATVTTTVAITTSPTTSATTSSIRDPNALAGQNGPDHALIGGIVAVVVFV 382
Query: 360 MLCLLIILGRYFARHKGTYFTHEAKGADDAADADTAIINAEGGQNNSEEKKEYFI 414
LC + +LGRY ARHKGTY T+EAKGA+DA DADTAIINAEG Q N+EEKKEYFI
Sbjct: 383 TLCSIFLLGRYLARHKGTYLTNEAKGAEDAPDADTAIINAEGSQVNAEEKKEYFI 437
>gi|21686977 cell adhesion molecule 4 [Homo sapiens]
Length = 388
Score = 296 bits (759), Expect = 2e-80
Identities = 158/388 (40%), Positives = 241/388 (62%), Gaps = 12/388 (3%)
Query: 29 LLLLFSAAALIPTGDGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRD 88
LLLL++AAA G GQ + T++VTV EG VA I+C++++ D S++ + NP RQT++F
Sbjct: 11 LLLLWAAAA--GPGAGQEVQTENVTVAEGGVAEITCRLHQYDGSIVVIQNPARQTLFFNG 68
Query: 89 FRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLM 148
R LKD RFQL FS +++ L++ + DEG YFCQLYT+ T+TVLV P N +
Sbjct: 69 TRALKDERFQLEEFSPRRVRIRLSDARLEDEGGYFCQLYTEDTHHQIATLTVLVAPENPV 128
Query: 149 IDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLK 208
+++ ++ AVEG E+E++C S+PA T+RW++ ELKG S +E +++V S + +
Sbjct: 129 VEV-REQAVEGGEVELSCLVPRSRPAATLRWYRDRKELKGVSSSQENGKVWSVASTVRFR 187
Query: 209 VHKEDDGVPVICQVEHPAVTG--NLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELT 266
V ++DDG +IC+ ++ A+ + QTQ L+VQY P I + Q + REGD L LT
Sbjct: 188 VDRKDDGGIIICEAQNQALPSGHSKQTQYVLDVQYSPTARIHAS---QAVVREGDTLVLT 244
Query: 267 CEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDY 326
C G P+P + W R ++ +P+ A G L + L DNGTY CEASN G A + Y
Sbjct: 245 CAVTGNPRPNQIRWNRGNESLPERAEAVGETLTLPGLVSADNGTYTCEASNKHGHARALY 304
Query: 327 MLYVYDSRAGEEGSIRAVDHAVIGGVVAVVVFAMLCLLIILGRYFARHKGTYFTHEAKGA 386
+L VYD A E +V +A++GG++A++VF ++C+L+ + R KG+Y THEA G
Sbjct: 305 VLVVYDPGAVVEAQ-TSVPYAIVGGILALLVFLIICVLVGMVWCSVRQKGSYLTHEASGL 363
Query: 387 DDAADADTAIINAEGGQNNSEEKKEYFI 414
D+ +A A +N G + + K+E+FI
Sbjct: 364 DEQGEAREAFLN---GSDGHKRKEEFFI 388
>gi|187608363 cell adhesion molecule 3 isoform 2 [Homo sapiens]
Length = 398
Score = 280 bits (717), Expect = 1e-75
Identities = 163/402 (40%), Positives = 233/402 (57%), Gaps = 16/402 (3%)
Query: 22 PGLRLRLLLLLFSAAALIPTG-----DGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQL 76
P L LLLLLF A P G D +T D TV+ G + CQV +DS +Q
Sbjct: 4 PAASLLLLLLLF-ACCWAPGGANLSQDDSQPWTSDETVVAGGTVVLKCQVKDHEDSSLQW 62
Query: 77 LNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYT 136
NP +QT+YF + R L+D+R QL+ + EL +S++NV+++DEG Y C ++T P + + +
Sbjct: 63 SNPAQQTLYFGEKRALRDNRIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKS 122
Query: 137 TITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGK-SEVEEW 195
+TVL P+ +I K + E + +NC + SKPA + W KG+ EL G+ + ++E
Sbjct: 123 LVTVLGIPQKPIITGYKSSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQED 182
Query: 196 SD--MYTVTSQLMLKVHKEDDGVPVICQVEHPAVTG-NLQTQRYLEVQYKPQVHIQMTYP 252
+ +TV+S + +V +EDDG ++C V H ++ G + T + +EV Y P I+ P
Sbjct: 183 PNGKTFTVSSSVTFQVTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPP 242
Query: 253 LQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYR 312
REG L L CE G P P W + + +P + L LNK+D+GTY
Sbjct: 243 ---HPREGQKLLLHCEGRGNPVPQQYLWEK-EGSVPPLKMTQESALIFPFLNKSDSGTYG 298
Query: 313 CEASNIVGKAHSDYMLYVYDSRAGEEGSIRAVDHAVIGGVVAVVVFAMLCLLIILGRYFA 372
C A++ +G + Y L V D S + HA+IGG+VA +VF +L +LI LG Y
Sbjct: 299 CTATSNMGSYKAYYTLNVNDPSPVPSSS--STYHAIIGGIVAFIVFLLLIMLIFLGHYLI 356
Query: 373 RHKGTYFTHEAKGADDAADADTAIINAEGGQNNSEEKKEYFI 414
RHKGTY THEAKG+DDA DADTAIINAEGGQ+ ++KKEYFI
Sbjct: 357 RHKGTYLTHEAKGSDDAPDADTAIINAEGGQSGGDDKKEYFI 398
>gi|11056046 cell adhesion molecule 3 isoform 1 [Homo sapiens]
Length = 432
Score = 274 bits (701), Expect = 9e-74
Identities = 154/387 (39%), Positives = 230/387 (59%), Gaps = 11/387 (2%)
Query: 32 LFSAAALIPTGDGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRP 91
++S+ ++ + D Q +T D TV+ G + CQV +DS +Q NP +QT+YF + R
Sbjct: 53 VWSSPDMLASQDSQP-WTSDETVVAGGTVVLKCQVKDHEDSSLQWSNPAQQTLYFGEKRA 111
Query: 92 LKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDI 151
L+D+R QL+ + EL +S++NV+++DEG Y C ++T P + + + +TVL P+ +I
Sbjct: 112 LRDNRIQLVTSTPHELSISISNVALADEGEYTCSIFTMPVRTAKSLVTVLGIPQKPIITG 171
Query: 152 QKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGK-SEVEEWSD--MYTVTSQLMLK 208
K + E + +NC + SKPA + W KG+ EL G+ + ++E + +TV+S + +
Sbjct: 172 YKSSLREKDTATLNCQSSGSKPAARLTWRKGDQELHGEPTRIQEDPNGKTFTVSSSVTFQ 231
Query: 209 VHKEDDGVPVICQVEHPAVTG-NLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTC 267
V +EDDG ++C V H ++ G + T + +EV Y P I+ P REG L L C
Sbjct: 232 VTREDDGASIVCSVNHESLKGADRSTSQRIEVLYTPTAMIRPDPP---HPREGQKLLLHC 288
Query: 268 EAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYM 327
E G P P W + + +P + L LNK+D+GTY C A++ +G + Y
Sbjct: 289 EGRGNPVPQQYLWEK-EGSVPPLKMTQESALIFPFLNKSDSGTYGCTATSNMGSYKAYYT 347
Query: 328 LYVYDSRAGEEGSIRAVDHAVIGGVVAVVVFAMLCLLIILGRYFARHKGTYFTHEAKGAD 387
L V D S + HA+IGG+VA +VF +L +LI LG Y RHKGTY THEAKG+D
Sbjct: 348 LNVNDPSPVPSSS--STYHAIIGGIVAFIVFLLLIMLIFLGHYLIRHKGTYLTHEAKGSD 405
Query: 388 DAADADTAIINAEGGQNNSEEKKEYFI 414
DA DADTAIINAEGGQ+ ++KKEYFI
Sbjct: 406 DAPDADTAIINAEGGQSGGDDKKEYFI 432
>gi|11386199 poliovirus receptor-related 3 [Homo sapiens]
Length = 549
Score = 103 bits (258), Expect = 2e-22
Identities = 92/354 (25%), Positives = 161/354 (45%), Gaps = 28/354 (7%)
Query: 3 SVVLPSGSQCAAAAAAAAPPGLRLR------LLLLLFSA---AALIPTGDGQNLFTKDVT 53
S + P G + ++A+ GL L+ LLLLLF + L G + VT
Sbjct: 8 SPLCPGGGKAQLSSASLLGAGLLLQPPTPPPLLLLLFPLLLFSRLCGALAGPIIVEPHVT 67
Query: 54 VIEGEVATISC--QVNKSDDSVI--QLLNPNRQTI------YFRDFRPLKDSRFQLLNFS 103
+ G+ ++ C +VN++ + ++ + QT+ Y + R N+S
Sbjct: 68 AVWGKNVSLKCLIEVNETITQISWEKIHGKSSQTVAVHHPQYGFSVQGEYQGRVLFKNYS 127
Query: 104 SSELKVSLTNVSISDEGRYFCQLYTDP--PQESYTTITVLVPPRNLMIDIQKDTAVEG-- 159
++ ++L N+ SD G+Y C+ T P +S TT+TVLV P +I D+ ++G
Sbjct: 128 LNDATITLHNIGFSDSGKYICKAVTFPLGNAQSSTTVTVLVEPTVSLIK-GPDSLIDGGN 186
Query: 160 EEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVI 219
E + C A KP I W +G+ + ++ T+ SQ L + G +
Sbjct: 187 ETVAAICIAATGKPVAHIDW-EGDLGEMESTTTSFPNETATIISQYKLFPTRFARGRRIT 245
Query: 220 CQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVT 279
C V+HPA+ +++ L++QY P+V + + R+G + L C A P P
Sbjct: 246 CVVKHPALEKDIRYSFILDIQYAPEVSVTGYDGNWFVGRKG--VNLKCNADANPPPFKSV 303
Query: 280 WVRVDDEMPQHAVLSGPNL-FINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYD 332
W R+D + P + S L F++ L +G Y C+ +N +G+ ++Y+ D
Sbjct: 304 WSRLDGQWPDGLLASDNTLHFVHPLTFNYSGVYICKVTNSLGQRSDQKVIYISD 357
>gi|51593098 class-I MHC-restricted T cell associated molecule [Homo
sapiens]
Length = 393
Score = 94.0 bits (232), Expect = 2e-19
Identities = 55/183 (30%), Positives = 94/183 (51%), Gaps = 2/183 (1%)
Query: 49 TKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELK 108
T+ +TV EG+ T+ C + +S +Q L P+ TI+ ++ LK+S++QLL+ S+++L
Sbjct: 23 TETITVEEGQTLTLKCVTSLRKNSSLQWLTPSGFTIFLNEYPALKNSKYQLLHHSANQLS 82
Query: 109 VSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEE-IEVNCT 167
+++ NV++ DEG Y C Y+D + VL P +++ GEE + + C+
Sbjct: 83 ITVPNVTLQDEGVYKCLHYSDSVSTKEVKVIVLATPFKPILEASVIRKQNGEEHVVLMCS 142
Query: 168 AMASKPATTIRWFKGNT-ELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPA 226
M SKP I W GN+ E+ G + E +D + L +H V C + H
Sbjct: 143 TMRSKPPPQITWLLGNSMEVSGGTLHEFETDGKKCNTTSTLIIHTYGKNSTVDCIIRHRG 202
Query: 227 VTG 229
+ G
Sbjct: 203 LQG 205
>gi|222136611 poliovirus receptor-related 4 [Homo sapiens]
Length = 510
Score = 91.3 bits (225), Expect = 1e-18
Identities = 107/390 (27%), Positives = 167/390 (42%), Gaps = 45/390 (11%)
Query: 22 PGLRLRLLLLLFSAAALIPTGDGQNLFTKDV-TVIEGEVATISCQVN-KSDDSVIQLL-- 77
P L LLLLL S P G+ L T DV TV+ G+ A + C S + V Q+
Sbjct: 12 PEAWLLLLLLLASFTGRCPAGE---LETSDVVTVVLGQDAKLPCFYRGDSGEQVGQVAWA 68
Query: 78 ----NPNRQTI------YFRDFRPLKDSRFQLLNFSSSEL--KVSLTNVSISDEGRYFCQ 125
Q + Y P + R + + L V L N +DEG Y C+
Sbjct: 69 RVDAGEGAQELALLHSKYGLHVSPAYEGRVEQPPPPRNPLDGSVLLRNAVQADEGEYECR 128
Query: 126 LYTDPPQ--ESYTTITVLVPPRNLMIDIQKDTAVE---GEEIEVNCTAMASKPATTIRWF 180
+ T P ++ + VLVPP + + A+E G + +CTA S PA ++ W
Sbjct: 129 VSTFPAGSFQARLRLRVLVPP---LPSLNPGPALEEGQGLTLAASCTAEGS-PAPSVTW- 183
Query: 181 KGNTELKGKSEVEEW--SDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLE 238
+TE+KG + + S VTS+ L + +G P+ C V HP + + + L
Sbjct: 184 --DTEVKGTTSSRSFKHSRSAAVTSEFHLVPSRSMNGQPLTCVVSHPGLLQDQRITHILH 241
Query: 239 VQYKPQVHIQ--MTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGP 296
V + + ++ L + REG L+ C + G+P P W R+D +P + G
Sbjct: 242 VSFLAEASVRGLEDQNLWHIGREGAMLK--CLSEGQPPP-SYNWTRLDGPLPSGVRVDGD 298
Query: 297 NLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDSRAGEEGSIRAVD----HAVIGGV 352
L L +G Y C SN S + V D +E S + VD V+ GV
Sbjct: 299 TLGFPPLTTEHSGIYVCHVSNEFSSRDSQVTVDVLDP---QEDSGKQVDLVSASVVVVGV 355
Query: 353 VAVVVFAMLCLLIILGRYFARHKGTYFTHE 382
+A ++F +L ++++L + R K T +
Sbjct: 356 IAALLFCLLVVVVVLMSRYHRRKAQQMTQK 385
>gi|209413732 poliovirus receptor isoform delta [Homo sapiens]
Length = 392
Score = 90.9 bits (224), Expect = 2e-18
Identities = 104/377 (27%), Positives = 156/377 (41%), Gaps = 32/377 (8%)
Query: 14 AAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVATISCQV---NKSD 70
A A AAA P L + LL+L + TGD V G+ T+ C + N
Sbjct: 2 ARAMAAAWPLLLVALLVLSWPPPG---TGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEV 58
Query: 71 DSVIQLL----NPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVS-------ISDE 119
V QL + F + S + L F ++ L L N S + DE
Sbjct: 59 THVSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDE 118
Query: 120 GRYFCQLYTDPPQESYTT---ITVLVPPRNLMIDIQKDTAVEGEEIEV-NCTAMASKPAT 175
G Y C L+ PQ S + + VL P+N ++QK + GE + + C + +P
Sbjct: 119 GNYTC-LFVTFPQGSRSVDIWLRVLAKPQNTA-EVQK-VQLTGEPVPMARCVSTGGRPPA 175
Query: 176 TIRWFKGNTELKGKSEVEEW-SDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQ 234
I W + S+V + S TVTS +L + DG V C+VEH +
Sbjct: 176 QITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLT 235
Query: 235 RYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLS 294
L V Y P+V I Y + +A LTC+A P+P W +P AV
Sbjct: 236 VNLTVYYPPEVSIS-GYDNNWYLGQNEAT-LTCDARSNPEPTGYNWSTTMGPLPPFAVAQ 293
Query: 295 GPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDSRAGEEGSIRAVDHAVIGGVVA 354
G L I ++K N T C +N +G ++ + V + E I +A+I V+
Sbjct: 294 GAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGISR--NAIIFLVLG 351
Query: 355 VVVFAMLCLLIILGRYF 371
++VF +L+ +G YF
Sbjct: 352 ILVF---LILLGIGIYF 365
>gi|209413726 poliovirus receptor isoform alpha [Homo sapiens]
Length = 417
Score = 90.9 bits (224), Expect = 2e-18
Identities = 104/377 (27%), Positives = 156/377 (41%), Gaps = 32/377 (8%)
Query: 14 AAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVATISCQV---NKSD 70
A A AAA P L + LL+L + TGD V G+ T+ C + N
Sbjct: 2 ARAMAAAWPLLLVALLVLSWPPPG---TGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEV 58
Query: 71 DSVIQLL----NPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVS-------ISDE 119
V QL + F + S + L F ++ L L N S + DE
Sbjct: 59 THVSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDE 118
Query: 120 GRYFCQLYTDPPQESYTT---ITVLVPPRNLMIDIQKDTAVEGEEIEV-NCTAMASKPAT 175
G Y C L+ PQ S + + VL P+N ++QK + GE + + C + +P
Sbjct: 119 GNYTC-LFVTFPQGSRSVDIWLRVLAKPQNTA-EVQK-VQLTGEPVPMARCVSTGGRPPA 175
Query: 176 TIRWFKGNTELKGKSEVEEW-SDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQ 234
I W + S+V + S TVTS +L + DG V C+VEH +
Sbjct: 176 QITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLT 235
Query: 235 RYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLS 294
L V Y P+V I Y + +A LTC+A P+P W +P AV
Sbjct: 236 VNLTVYYPPEVSIS-GYDNNWYLGQNEAT-LTCDARSNPEPTGYNWSTTMGPLPPFAVAQ 293
Query: 295 GPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDSRAGEEGSIRAVDHAVIGGVVA 354
G L I ++K N T C +N +G ++ + V + E I +A+I V+
Sbjct: 294 GAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGISR--NAIIFLVLG 351
Query: 355 VVVFAMLCLLIILGRYF 371
++VF +L+ +G YF
Sbjct: 352 ILVF---LILLGIGIYF 365
>gi|112789532 poliovirus receptor related 2 isoform delta precursor
[Homo sapiens]
Length = 538
Score = 88.6 bits (218), Expect = 1e-17
Identities = 73/276 (26%), Positives = 113/276 (40%), Gaps = 17/276 (6%)
Query: 89 FRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQE--SYTTITVLVPPRN 146
F K S Q + ++L +++ DEG Y C+ T P T + V+ P+N
Sbjct: 105 FVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKN 164
Query: 147 LMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKG-NTELKGKSEVEEWSDMYTVTSQL 205
+ QK T + C + +P I W + E K + TVTS+
Sbjct: 165 -QAEAQKVTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRF 223
Query: 206 MLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALEL 265
L DGV V C+VEH + L V+Y P+V I Y DA L
Sbjct: 224 TLVPSGRADGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSIS-GYDDNWYLGRTDAT-L 281
Query: 266 TCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSD 325
+C+ P+P W P AV G L I+ ++ N T+ C +N VG ++
Sbjct: 282 SCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAE 341
Query: 326 YMLYVYD----SRAGEEGSIRAVDHAVIGGVVAVVV 357
+++V + + AG G I IGG++A ++
Sbjct: 342 QVIFVRETPNTAGAGATGGI-------IGGIIAAII 370
>gi|5360210 poliovirus receptor related 2 isoform alpha precursor
[Homo sapiens]
Length = 479
Score = 87.4 bits (215), Expect = 2e-17
Identities = 75/291 (25%), Positives = 117/291 (40%), Gaps = 7/291 (2%)
Query: 89 FRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQE--SYTTITVLVPPRN 146
F K S Q + ++L +++ DEG Y C+ T P T + V+ P+N
Sbjct: 105 FVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKN 164
Query: 147 LMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKG-NTELKGKSEVEEWSDMYTVTSQL 205
+ QK T + C + +P I W + E K + TVTS+
Sbjct: 165 -QAEAQKVTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRF 223
Query: 206 MLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALEL 265
L DGV V C+VEH + L V+Y P+V I Y DA L
Sbjct: 224 TLVPSGRADGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSIS-GYDDNWYLGRTDAT-L 281
Query: 266 TCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSD 325
+C+ P+P W P AV G L I+ ++ N T+ C +N VG ++
Sbjct: 282 SCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAE 341
Query: 326 YMLYVYDSRAGEEGSIRAVDHAVIGGVVAV-VVFAMLCLLIILGRYFARHK 375
+++V ++ + + +GG + V ++ A L IL R R K
Sbjct: 342 QVIFVRETPRASPRDVGPLVWGAVGGTLLVLLLLAGGSLAFILLRVRRRRK 392
>gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens]
Length = 517
Score = 84.0 bits (206), Expect = 2e-16
Identities = 84/328 (25%), Positives = 143/328 (43%), Gaps = 35/328 (10%)
Query: 74 IQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPP-- 131
+ + NP+ +R R + L S ++ + L+ + + DEG Y C+ T P
Sbjct: 78 VAIYNPSMGVSVLAPYR----ERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGN 133
Query: 132 QESYTTITVLVPPRNLMIDIQKD-TAVEGEEIEV---NCTAMASKPATTIRWFKGNTELK 187
+ES +TV+ P N + Q A +G++ +V CT+ KP + + W T LK
Sbjct: 134 RESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSW---ETRLK 190
Query: 188 GKSEVEEW---SDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQ 244
G++E +E + TV S+ L +E + C V + + L VQY+P+
Sbjct: 191 GEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYH--MDRFKESLTLNVQYEPE 248
Query: 245 VHIQ---MTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFIN 301
V I+ + LQ + ++LTC+A P W ++ +P+ LF
Sbjct: 249 VTIEGFDGNWYLQRMD-----VKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFK 303
Query: 302 N-LNKTDNGTYRCEASNIV----GKAHSDYMLYVYDSRAGEEG-SIRAVDHAVIGGVVAV 355
+N + GTY CEA+N + G+ + + Y E G V A+IGGV
Sbjct: 304 GPINYSLAGTYICEATNPIGTRSGQVEVNITEFPYTPSPPEHGRRAGPVPTAIIGGVAGS 363
Query: 356 VVFAMLC---LLIILGRYFARHKGTYFT 380
++ ++ +++ L R KG Y T
Sbjct: 364 ILLVLIVVGGIVVALRRRRHTFKGDYST 391
>gi|209413728 poliovirus receptor isoform beta [Homo sapiens]
Length = 372
Score = 83.6 bits (205), Expect = 3e-16
Identities = 96/358 (26%), Positives = 141/358 (39%), Gaps = 27/358 (7%)
Query: 14 AAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVATISCQV---NKSD 70
A A AAA P L + LL+L + TGD V G+ T+ C + N
Sbjct: 2 ARAMAAAWPLLLVALLVLSWPPPG---TGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEV 58
Query: 71 DSVIQLL----NPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVS-------ISDE 119
V QL + F + S + L F ++ L L N S + DE
Sbjct: 59 THVSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDE 118
Query: 120 GRYFCQLYTDPPQESYTT---ITVLVPPRNLMIDIQKDTAVEGEEIEV-NCTAMASKPAT 175
G Y C L+ PQ S + + VL P+N ++QK + GE + + C + +P
Sbjct: 119 GNYTC-LFVTFPQGSRSVDIWLRVLAKPQNTA-EVQK-VQLTGEPVPMARCVSTGGRPPA 175
Query: 176 TIRWFKGNTELKGKSEVEEW-SDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQ 234
I W + S+V + S TVTS +L + DG V C+VEH +
Sbjct: 176 QITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLT 235
Query: 235 RYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLS 294
L V Y P+V I Y + +A LTC+A P+P W +P AV
Sbjct: 236 VNLTVYYPPEVSIS-GYDNNWYLGQNEAT-LTCDARSNPEPTGYNWSTTMGPLPPFAVAQ 293
Query: 295 GPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDSRAGEEGSIRAVDHAVIGGV 352
G L I ++K N T C +N +G ++ + V + E + G V
Sbjct: 294 GAQLLIRPVDKPINTTLICNVTNALGARQAELTVQVKEGPPSEHSGTEHASASANGHV 351
>gi|209413730 poliovirus receptor isoform gamma [Homo sapiens]
Length = 364
Score = 83.2 bits (204), Expect = 4e-16
Identities = 98/358 (27%), Positives = 142/358 (39%), Gaps = 30/358 (8%)
Query: 14 AAAAAAAPPGLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVATISCQV---NKSD 70
A A AAA P L + LL+L + TGD V G+ T+ C + N
Sbjct: 2 ARAMAAAWPLLLVALLVLSWPPPG---TGDVVVQAPTQVPGFLGDSVTLPCYLQVPNMEV 58
Query: 71 DSVIQLL----NPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVS-------ISDE 119
V QL + F + S + L F ++ L L N S + DE
Sbjct: 59 THVSQLTWARHGESGSMAVFHQTQGPSYSESKRLEFVAARLGAELRNASLRMFGLRVEDE 118
Query: 120 GRYFCQLYTDPPQESYTT---ITVLVPPRNLMIDIQKDTAVEGEEIEV-NCTAMASKPAT 175
G Y C L+ PQ S + + VL P+N ++QK + GE + + C + +P
Sbjct: 119 GNYTC-LFVTFPQGSRSVDIWLRVLAKPQNTA-EVQK-VQLTGEPVPMARCVSTGGRPPA 175
Query: 176 TIRWFKGNTELKGKSEVEEW-SDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQ 234
I W + S+V + S TVTS +L + DG V C+VEH +
Sbjct: 176 QITWHSDLGGMPNTSQVPGFLSGTVTVTSLWILVPSSQVDGKNVTCKVEHESFEKPQLLT 235
Query: 235 RYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLS 294
L V Y P+V I Y + +A LTC+A P+P W +P AV
Sbjct: 236 VNLTVYYPPEVSIS-GYDNNWYLGQNEAT-LTCDARSNPEPTGYNWSTTMGPLPPFAVAQ 293
Query: 295 GPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDSRAGEEGSIRAVDHAVIGGV 352
G L I ++K N T C +N +G ++ + V + E S A H V
Sbjct: 294 GAQLLIRPVDKPINTTLICNVTNALGARQAELTVQV---KGTEHASASANGHVSYSAV 348
>gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens]
Length = 458
Score = 80.9 bits (198), Expect = 2e-15
Identities = 82/326 (25%), Positives = 141/326 (43%), Gaps = 33/326 (10%)
Query: 74 IQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPP-- 131
+ + NP+ +R R + L S ++ + L+ + + DEG Y C+ T P
Sbjct: 78 VAIYNPSMGVSVLAPYR----ERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGN 133
Query: 132 QESYTTITVLVPPRNLMIDIQKD-TAVEGEEIEV---NCTAMASKPATTIRWFKGNTELK 187
+ES +TV+ P N + Q A +G++ +V CT+ KP + + W T LK
Sbjct: 134 RESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSW---ETRLK 190
Query: 188 GKSEVEEW---SDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQ 244
G++E +E + TV S+ L +E + C V + + L VQY+P+
Sbjct: 191 GEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYH--MDRFKESLTLNVQYEPE 248
Query: 245 VHIQ---MTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFIN 301
V I+ + LQ + ++LTC+A P W ++ +P+ LF
Sbjct: 249 VTIEGFDGNWYLQRMD-----VKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFK 303
Query: 302 N-LNKTDNGTYRCEASNIVGKAHSDYMLYVYDSRAGEEGSIRAVDHAVIGGVVAVVVFAM 360
+N + GTY CEA+N +G + + + + G A ++ G VAV
Sbjct: 304 GPINYSLAGTYICEATNPIGTRSGQVEVNITEKPRPQRGLGSAA--RLLAGTVAV----F 357
Query: 361 LCLLIILGRYFARHKGTYFTHEAKGA 386
L L+ +L +F ++ E GA
Sbjct: 358 LILVAVLTVFFLYNRQQKSPPETDGA 383
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 80.5 bits (197), Expect = 3e-15
Identities = 64/255 (25%), Positives = 111/255 (43%), Gaps = 14/255 (5%)
Query: 85 YFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPP 144
+F+D + + S + F + + V ++D G + C+ + + ++ P
Sbjct: 4146 WFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEP 4205
Query: 145 RNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQ 204
+ + + G + + T S P T IRWFKGN EL + + S
Sbjct: 4206 PSFVTKPGSKDVLPGSAVCLKSTFQGSTPLT-IRWFKGNKELVSGGSC--YITKEALESS 4262
Query: 205 LMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALE 264
L L + K D C+V + V G ++ L V+ +P ++ P Q L ++GDA +
Sbjct: 4263 LELYLVKTSDSGTYTCKVSN--VAGGVECSANLFVK-EPATFVEKLEPSQ-LLKKGDATQ 4318
Query: 265 LTCEAIGKPQPVMVTWVRVDDEMPQHA------VLSGPNLFINNLNKTDNGTYRCEASNI 318
L C+ G P P+ +TW D E+ + + V S L + ++ D+G Y CEA N
Sbjct: 4319 LACKVTGTP-PIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNE 4377
Query: 319 VGKAHSDYMLYVYDS 333
G H ++ V +S
Sbjct: 4378 AGSDHCSSIVIVKES 4392
Score = 68.2 bits (165), Expect = 1e-11
Identities = 73/297 (24%), Positives = 123/297 (41%), Gaps = 40/297 (13%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
KD+ G T++C++N S Q ++RD L+D +F + +
Sbjct: 6182 KDIEQTVGLPVTLTCRLNGSAPI---------QVCWYRDGVLLRDDENLQTSFVDNVATL 6232
Query: 110 SLTNVSISDEGRYFCQLYTDP--PQESYTTITVLVPPRNLMIDIQKDT--AVEGEEIEVN 165
+ +S G+Y C ++P S +T P ++ DI+ + + GE +
Sbjct: 6233 KILQTDLSHSGQYSCSA-SNPLGTASSSARLTAREPKKSPFFDIKPVSIDVIAGESADFE 6291
Query: 166 CTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQ------LMLKVHKEDDGVPVI 219
C ++P I W K N E++ YT+T +LKV K D G
Sbjct: 6292 CHVTGAQPMR-ITWSKDNKEIRPGGN-------YTITCVGNTPHLRILKVGKGDSG-QYT 6342
Query: 220 CQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVT 279
CQ + G L V+ P+ ++ + ++G++++L C+ G P+ + V+
Sbjct: 6343 CQATNDV--GKDMCSAQLSVKEPPKFVKKLE--ASKVAKQGESIQLECKISGSPE-IKVS 6397
Query: 280 WVRVDDEMPQ------HAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYV 330
W R D E+ + + S L IN + D+G Y CEA N VG A L V
Sbjct: 6398 WFRNDSELHESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTV 6454
Score = 66.2 bits (160), Expect = 5e-11
Identities = 70/317 (22%), Positives = 134/317 (42%), Gaps = 31/317 (9%)
Query: 34 SAAALIPTGDGQN-----LFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRD 88
S+A LI T +G+N + V + GE A C V + + + +D
Sbjct: 8140 SSARLILT-EGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVS---------WAKD 8189
Query: 89 FRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTT-ITV---LVPP 144
R ++ +++ + +++ V D G+Y C + ++S T + + L+PP
Sbjct: 8190 SREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPP 8249
Query: 145 RNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQ 204
+ EG ++ S+P T + W+K N E++ S E T+ Q
Sbjct: 8250 SFTKRLSETVEETEGNSFKLEGRVAGSQPIT-VAWYKNNIEIQPTSNCEITFKNNTLVLQ 8308
Query: 205 LMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALE 264
+ K D G+ C+V + A + + ++ KP V Q P+ EG+ ++
Sbjct: 8309 VR-KAGMNDAGL-YTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVT--VSEGEYVQ 8364
Query: 265 LTCEAIGKPQPVMVTWVRVDDEMP-----QHAVLSGPNLF-INNLNKTDNGTYRCEASNI 318
L+C G +P+ + W++ E+ + SG + + ++ K D+G Y C+ASN+
Sbjct: 8365 LSCHVQGS-EPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNV 8423
Query: 319 VGKAHSDYMLYVYDSRA 335
G + + + D A
Sbjct: 8424 AGSDTTKSKVTIKDKPA 8440
Score = 65.9 bits (159), Expect = 7e-11
Identities = 63/250 (25%), Positives = 108/250 (43%), Gaps = 14/250 (5%)
Query: 109 VSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTA 168
+ + N + D G+Y C++ + ++ + + P + +++ A G+ + + C
Sbjct: 6043 LEILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQ- 6101
Query: 169 MASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVT 228
+A P T+ W+KG+T+L+ E + V + + KV+ D G C+ E+ T
Sbjct: 6102 VAGTPEITVSWYKGDTKLRPTPEYRTYFTN-NVATLVFNKVNINDSG-EYTCKAENSIGT 6159
Query: 229 GNLQTQ-RYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRV---- 283
+ +T R E Q P Q+ Q + G + LTC G P+ V W R
Sbjct: 6160 ASSKTVFRIQERQLPPSFARQLKDIEQTV---GLPVTLTCRLNGSA-PIQVCWYRDGVLL 6215
Query: 284 -DDEMPQHAVLSG-PNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDSRAGEEGSI 341
DDE Q + + L I + + +G Y C ASN +G A S L + + I
Sbjct: 6216 RDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDI 6275
Query: 342 RAVDHAVIGG 351
+ V VI G
Sbjct: 6276 KPVSIDVIAG 6285
Score = 62.4 bits (150), Expect = 7e-10
Identities = 56/245 (22%), Positives = 112/245 (45%), Gaps = 15/245 (6%)
Query: 84 IYFRDFRPL-KDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPP-QESYTTITVL 141
++F+D + ++S +++S + + + V ++ G+Y CQ+ D QE + T++VL
Sbjct: 7524 VWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVL 7583
Query: 142 VPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTV 201
P ++ + G+ + CT +A P + +WFK EL ++ + S V
Sbjct: 7584 -EPATIVEKPESIKVTTGDTCTLECT-VAGTPELSTKWFKDGKELTSDNKYKI-SFFNKV 7640
Query: 202 TSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGD 261
+ ++ V D GV +V++P + + + P + GL+ G
Sbjct: 7641 SGLKIINVAPSDSGVYSF-EVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLS--GS 7697
Query: 262 ALELTCEAIGKPQPVMVTWVRVDDEMPQ----HAVLSGPN--LFINNLNKTDNGTYRCEA 315
++ + C+ G P P+ V+W +E+ L+ L +N L ++D+G Y C A
Sbjct: 7698 SVVMECKVYGSP-PISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIA 7756
Query: 316 SNIVG 320
+N+ G
Sbjct: 7757 TNMAG 7761
Score = 62.0 bits (149), Expect = 1e-09
Identities = 59/251 (23%), Positives = 105/251 (41%), Gaps = 25/251 (9%)
Query: 85 YFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPP 144
+FR R L + F + ++ L N+ IS G Y C + + Q S TT + P
Sbjct: 5926 WFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEP 5985
Query: 145 RNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQ 204
+ + + G+ I + T + P ++ W K + E ++ T
Sbjct: 5986 AAFLKRLSDHSVEPGKSIILESTYTGTLP-ISVTWKKDGFNI----TTSEKCNIVTTEKT 6040
Query: 205 LMLKV--HKEDDGVPVICQVEHPA---VTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTRE 259
+L++ + D C++E+ A V G L + +P + PL+
Sbjct: 6041 CILEILNSTKRDAGQYSCEIENEAGRDVCGALVS------TLEPPYFVTELEPLEAAV-- 6092
Query: 260 GDALELTCEAIGKPQPVMVTWVRVDDEM---PQHAVLSGPN---LFINNLNKTDNGTYRC 313
GD++ L C+ G P+ + V+W + D ++ P++ N L N +N D+G Y C
Sbjct: 6093 GDSVSLQCQVAGTPE-ITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYTC 6151
Query: 314 EASNIVGKAHS 324
+A N +G A S
Sbjct: 6152 KAENSIGTASS 6162
Score = 60.8 bits (146), Expect = 2e-09
Identities = 61/262 (23%), Positives = 112/262 (42%), Gaps = 18/262 (6%)
Query: 79 PNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTI 138
P + ++++D R L+ S+ + + + + NV SD G Y C+ + ++
Sbjct: 5544 PPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCT 5603
Query: 139 TVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDM 198
L P + + T V GE E+ + ++P ++W K E+ +SE + +
Sbjct: 5604 VKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQP-IFVQWLKEKEEVIRESENIRITFV 5662
Query: 199 YTVTSQLMLKVHKEDDGVPVICQVEHP-AVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLT 257
V + K + G ICQ+++ + N+ T LE P V ++ P+
Sbjct: 5663 ENVATLQFAKAEPANAG-KYICQIKNDGGMRENMATLMVLE----PAVIVEKAGPM--TV 5715
Query: 258 REGDALELTCEAIGKPQPVMVTWVRVDDEM---PQHAVLSGPN----LFINNLNKTDNGT 310
G+ L C+ G P+ + V W + D ++ Q S N L I ++ + D GT
Sbjct: 5716 TVGETCTLECKVAGTPE-LSVEWYK-DGKLLTSSQKHKFSFYNKISSLRILSVERQDAGT 5773
Query: 311 YRCEASNIVGKAHSDYMLYVYD 332
Y + N VGK+ ++ V D
Sbjct: 5774 YTFQVQNNVGKSSCTAVVDVSD 5795
Score = 59.7 bits (143), Expect = 5e-09
Identities = 58/243 (23%), Positives = 109/243 (44%), Gaps = 16/243 (6%)
Query: 85 YFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPP 144
+F+D L + S ++L +V S G+Y C + D +S TT+ ++ P
Sbjct: 5363 WFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEP 5422
Query: 145 RNLMIDIQKDTAVE-GEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTS 203
+ ++ V+ G+ + C +A P + WF+ EL S+ + + +V
Sbjct: 5423 PKFVKKLEASKIVKAGDSSRLEC-KIAGSPEIRVVWFRNEHELPA-SDKYRMTFIDSVAV 5480
Query: 204 QLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDAL 263
M + ED G IC+ ++PA + + T+ ++ +P V ++P T + +
Sbjct: 5481 IQMNNLSTEDSG-DFICEAQNPAGSTSCSTKVIVK---EPPVF--SSFPPIVETLKNAEV 5534
Query: 264 ELTCEAIGKPQPVMVTWVRVDDEM---PQHAVLS---GPNLFINNLNKTDNGTYRCEASN 317
L CE G P P V W + ++ ++ + S ++ I N++ +D G Y C+A N
Sbjct: 5535 SLECELSGTP-PFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSDIGEYHCKAQN 5593
Query: 318 IVG 320
VG
Sbjct: 5594 EVG 5596
Score = 59.3 bits (142), Expect = 6e-09
Identities = 64/287 (22%), Positives = 111/287 (38%), Gaps = 23/287 (8%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
K + I+G + C V S IQ +F+D + + S +F + +
Sbjct: 4682 KKMDSIKGSFIDLECIVAGSHPISIQ---------WFKDDQEISASEKYKFSFHDNTAFL 4732
Query: 110 SLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAM 169
++ + +D G Y C + + P + Q +++
Sbjct: 4733 EISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVG 4792
Query: 170 ASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTG 229
+ P T I+WFK N EL + W D ++ L L K D ICQ+ + T
Sbjct: 4793 GTAPMT-IKWFKDNKELHSGAARSVWKD--DTSTSLELFAAKATDSGTYICQLSNDVGTA 4849
Query: 230 NLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMP- 288
+ +++ +P I+ P+ L R G + C+ G P+ + V+W +E+
Sbjct: 4850 TSKATLFVK---EPPQFIKKPSPVLVL-RNGQSTTFECQITGTPK-IRVSWYLDGNEITA 4904
Query: 289 --QHAV--LSGPNLF-INNLNKTDNGTYRCEASNIVGKAHSDYMLYV 330
+H + + G F I+ ++GTY CEA N G A L V
Sbjct: 4905 IQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTASCSIELKV 4951
Score = 58.9 bits (141), Expect = 8e-09
Identities = 70/302 (23%), Positives = 124/302 (41%), Gaps = 35/302 (11%)
Query: 46 NLFTKD-VTVIE----------GEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKD 94
NLF K+ T +E G+ ++C+V + P + +F + R +K+
Sbjct: 4292 NLFVKEPATFVEKLEPSQLLKKGDATQLACKVTGT---------PPIKITWFANDREIKE 4342
Query: 95 SRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKD 154
S ++F S + LT+V I D G Y C+ + + ++I V+V K
Sbjct: 4343 SSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSI-VIVKESPYFTKEFKP 4401
Query: 155 TAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDD 214
V E + +A P I WFK NT L+ + + + + V+ Q+ LK D
Sbjct: 4402 IEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQI-LKFVAADA 4460
Query: 215 GVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQ 274
G C+V + + + L I+ T L+G T A + T +
Sbjct: 4461 G-EYQCRVTNEVGSSICSARVTLREPPSFIKKIESTSSLRGGTA---AFQATLKG---SL 4513
Query: 275 PVMVTWVRVDDEMPQHAVL------SGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYML 328
P+ VTW++ DE+ + + + +L+++ + +G Y C+A N G +L
Sbjct: 4514 PITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALL 4573
Query: 329 YV 330
V
Sbjct: 4574 SV 4575
Score = 58.5 bits (140), Expect = 1e-08
Identities = 59/277 (21%), Positives = 107/277 (38%), Gaps = 24/277 (8%)
Query: 54 VIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTN 113
++ GE A + C++ S P Q +F++ + L +S + F +SE + +T+
Sbjct: 3749 MLPGESARLHCKLKGS---------PVIQVTWFKNNKELSESNTVRMYFVNSEAILDITD 3799
Query: 114 VSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKP 173
V + D G Y C+ D +S +T V+ P + + ++ V G + C + P
Sbjct: 3800 VKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGP 3859
Query: 174 ATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQT 233
I WFK +++ + +S V ++ + D G G + T
Sbjct: 3860 -FEISWFKDKKQIRSSKKYRLFSQKSLVCLEI-FSFNSADVGEYECVVANEVGKCGCMAT 3917
Query: 234 QRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTW------VRVDDEM 287
E P ++ L L + L+ A+ +P+ VTW +R D ++
Sbjct: 3918 HLLKE----PPTFVKKVDDLIALGGQTVTLQ---AAVRGSEPISVTWMKGQEVIREDGKI 3970
Query: 288 PQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHS 324
L I ++ + G Y C A N G S
Sbjct: 3971 KMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTS 4007
Score = 55.5 bits (132), Expect = 9e-08
Identities = 62/282 (21%), Positives = 121/282 (42%), Gaps = 23/282 (8%)
Query: 62 ISCQVNKSDDSVIQLLNPNRQTI---YFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISD 118
+S V + D + +Q+ + I +F+D + L ++ + + + + + D
Sbjct: 4586 VSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKD 4645
Query: 119 EGRYFCQLYTDPPQES----YTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPA 174
G Y ++ D + S + +++PP + ++K +++G I++ C S P
Sbjct: 4646 SGEYTFEVQNDVGRSSCKARINVLDLIIPP-SFTKKLKKMDSIKGSFIDLECIVAGSHPI 4704
Query: 175 TTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQ 234
+ I+WFK + E+ SE ++S + T+ L + + D C + A G+ Q
Sbjct: 4705 S-IQWFKDDQEISA-SEKYKFS-FHDNTAFLEISQLEGTDSGTYTCSATNKA--GHNQCS 4759
Query: 235 RYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLS 294
+L V+ P + P ++L +G P+ + W + + E+ A S
Sbjct: 4760 GHLTVKEPPYF---VEKPQSQDVNPNTRVQLKA-LVGGTAPMTIKWFKDNKELHSGAARS 4815
Query: 295 ------GPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYV 330
+L + TD+GTY C+ SN VG A S L+V
Sbjct: 4816 VWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFV 4857
Score = 55.5 bits (132), Expect = 9e-08
Identities = 56/287 (19%), Positives = 111/287 (38%), Gaps = 20/287 (6%)
Query: 52 VTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSL 111
+TV+ GE A + + + +Q L + I ++S + F + +
Sbjct: 5619 LTVVAGEPAELQASIEGAQPIFVQWLKEKEEVI--------RESENIRITFVENVATLQF 5670
Query: 112 TNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMAS 171
++ G+Y CQ+ D +++ P ++ T GE + C +A
Sbjct: 5671 AKAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIVEKAGPMTVTVGETCTLECK-VAG 5729
Query: 172 KPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNL 231
P ++ W+K +L S+ ++S ++S +L V ++D G QV++ +
Sbjct: 5730 TPELSVEWYKDG-KLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTF-QVQNNVGKSSC 5787
Query: 232 QTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHA 291
+ + P + G+ G + L C+ G P+ V W ++ A
Sbjct: 5788 TAVVDVSDRAVPPSFTRRLKNTGGVL--GASCILECKVAGS-SPISVAWFHEKTKIVSGA 5844
Query: 292 VLSGP------NLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYD 332
L +N+L+ +D G Y C A+N+ G +L V +
Sbjct: 5845 KYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQE 5891
Score = 54.7 bits (130), Expect = 2e-07
Identities = 60/296 (20%), Positives = 113/296 (38%), Gaps = 54/296 (18%)
Query: 48 FTKDVTVIE---GEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSS 104
FTK +T ++ G + C+V+ S Q +F+D + + S L
Sbjct: 5239 FTKKLTKMDKVLGSSIHMECKVSGSLPISAQ---------WFKDGKEISTSAKYRLVCHE 5289
Query: 105 SELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEV 164
+ + + N+ + D Y C++ ++ + I + P + ++ + A+ +E
Sbjct: 5290 RSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTVEF 5349
Query: 165 NCTAMASKPATTIRWFKGNTELK-------GKSEVEEWSDMYTV----TSQLMLKVHKE- 212
+ P I+WFK + EL G + ++Y+V T Q V +
Sbjct: 5350 K-AILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSVDASKTGQYTCHVTNDV 5408
Query: 213 --DDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAI 270
D ++ E P L+ + + + GD+ L C+
Sbjct: 5409 GSDSCTTMLLVTEPPKFVKKLEASK--------------------IVKAGDSSRLECKIA 5448
Query: 271 GKPQPVMVTWVRVDDEMP------QHAVLSGPNLFINNLNKTDNGTYRCEASNIVG 320
G P+ + V W R + E+P + S + +NNL+ D+G + CEA N G
Sbjct: 5449 GSPE-IRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAG 5503
Score = 54.7 bits (130), Expect = 2e-07
Identities = 64/269 (23%), Positives = 110/269 (40%), Gaps = 30/269 (11%)
Query: 100 LNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAV-- 157
+ F ++ L + + ++D G Y C++ D T+ V+ P+ + Q T V
Sbjct: 8298 ITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVFDQHLTPVTV 8357
Query: 158 -EGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGV 216
EGE ++++C S+P I+W K E+K + T+ L L+ + D
Sbjct: 8358 SEGEYVQLSCHVQGSEPIR-IQWLKAGREIKPSDRCS--FSFASGTAVLELRDVAKADSG 8414
Query: 217 PVICQVEHPAVTGNLQTQRYLEVQYKPQVH------------IQMTYPLQGLTREGDALE 264
+C+ + V G+ T+ + ++ KP V ++ P E
Sbjct: 8415 DYVCKASN--VAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTAT 8472
Query: 265 LTCEAIGKPQPVMVTWVRVD-DEMPQ------HAVLSGPNLFINNLNKTDNGTYRCEASN 317
+ G P P V W + ++ Q H L I + KTD+G YRC A N
Sbjct: 8473 FIAKVGGDPIP-NVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGLYRCVAFN 8531
Query: 318 IVGKAHSDYMLYVYDSRAGE--EGSIRAV 344
G+ S+ L V + + E EG +RA+
Sbjct: 8532 EHGEIESNVNLQVDERKKQEKIEGDLRAM 8560
Score = 54.3 bits (129), Expect = 2e-07
Identities = 51/258 (19%), Positives = 103/258 (39%), Gaps = 22/258 (8%)
Query: 92 LKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDI 151
+++S ++F + + L + S+ G+Y CQ+ D + + ++ P ++
Sbjct: 6592 IRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKP 6651
Query: 152 QKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHK 211
+ T G + C + P + +WFK EL S+ + + V S +
Sbjct: 6652 EPMTVTTGNPFALEC-VVTGTPELSAKWFKDGRELSADSK-HHITFINKVASLKIPCAEM 6709
Query: 212 EDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIG 271
D G+ +V++ N ++ + P I+ + + G ++ L C G
Sbjct: 6710 SDKGL-YSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDVNAIL--GASVVLECRVSG 6766
Query: 272 KPQPVMVTWVRVDDEMPQHAVLSGP-----------NLFINNLNKTDNGTYRCEASNIVG 320
P+ V W + +E ++SGP L ++ L +D G Y C A+N+ G
Sbjct: 6767 S-APISVGWFQDGNE-----IVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAG 6820
Query: 321 KAHSDYMLYVYDSRAGEE 338
+L V + + E+
Sbjct: 6821 SDECSAVLTVQEPPSFEQ 6838
Score = 53.9 bits (128), Expect = 3e-07
Identities = 61/290 (21%), Positives = 116/290 (40%), Gaps = 27/290 (9%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
+ + V G+ T+ C V + P T +F+D + L ++F + +
Sbjct: 7593 ESIKVTTGDTCTLECTVAGT---------PELSTKWFKDGKELTSDNKYKISFFNKVSGL 7643
Query: 110 SLTNVSISDEGRYFCQLYTDPPQESYTT---ITVLVPPRNLMIDIQKDTAVEGEEIEVNC 166
+ NV+ SD G Y ++ ++S T ++ P + +++ + G + + C
Sbjct: 7644 KIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMEC 7703
Query: 167 TAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPA 226
S P ++ WF E+ + + + + T L + + +E D C + A
Sbjct: 7704 KVYGS-PPISVSWFHEGNEISSGRKYQ--TTLTDNTCALTVNMLEESDSGDYTCIATNMA 7760
Query: 227 VTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDE 286
G+ + L V+ +P +Q P+ LT G + T G P P V+W + E
Sbjct: 7761 --GSDECSAPLTVR-EPPSFVQKPDPMDVLT--GTNVTFTSIVKGTP-PFSVSWFKGSSE 7814
Query: 287 MPQ------HAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYV 330
+ S L + +++ + +G Y C SN GKA LY+
Sbjct: 7815 LVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYI 7864
Score = 53.1 bits (126), Expect = 4e-07
Identities = 73/293 (24%), Positives = 118/293 (40%), Gaps = 32/293 (10%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
KDV G C++N S+ Q +++D LKD +F + +
Sbjct: 7123 KDVHETLGFPVAFECRINGSEPL---------QVSWYKDGVLLKDDANLQTSFVHNVATL 7173
Query: 110 SLTNVSISDEGRYFCQLYTDPPQESYTTITVL----VPPRNLMIDIQKDTAVEGEEIEVN 165
+ S G+Y C S + +L VPP + + D A+ GE
Sbjct: 7174 QILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSVDLAL-GESGTFK 7232
Query: 166 CTAMASKPATTIRWFKGNTELK--GKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVE 223
C + P I W K N E++ G ++ + T+T +LKV K D G C
Sbjct: 7233 CHVTGTAPIK-ITWAKDNREIRPGGNYKMTLVENTATLT---VLKVGKGDAG-QYTCYAS 7287
Query: 224 HPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRV 283
+ + G L VQ P+ I+ P + + ++ + C+ G P+ + V W +
Sbjct: 7288 N--IAGKDSCSAQLGVQEPPRF-IKKLEPSR-IVKQDEFTRYECKIGGSPE-IKVLWYKD 7342
Query: 284 DDEMPQHA------VLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYV 330
+ E+ + + V S L ++NL+ D+G Y CEA N G A S L V
Sbjct: 7343 ETEIQESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKV 7395
Score = 52.4 bits (124), Expect = 8e-07
Identities = 57/256 (22%), Positives = 105/256 (41%), Gaps = 18/256 (7%)
Query: 85 YFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPP 144
+++D R L+ + + + + + NV +D G Y C+ D ++ L P
Sbjct: 7432 WYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIALKAP 7491
Query: 145 RNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQ 204
+ + + V G+E+++ T ++P + + WFK E+ +S+ S + +
Sbjct: 7492 PRFVKKLSDISTVVGKEVQLQTTIEGAEPISVV-WFKDKGEIVRESDNIWISYSENIATL 7550
Query: 205 LMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALE 264
+V + G CQ+++ A G + L V +P ++ ++ T GD
Sbjct: 7551 QFSRVEPANAG-KYTCQIKNDA--GMQECFATLSV-LEPATIVEKPESIKVTT--GDTCT 7604
Query: 265 LTCEAIGKPQPVMVTWVRVDDEMPQ--------HAVLSGPNLFINNLNKTDNGTYRCEAS 316
L C G P+ + W + E+ +SG L I N+ +D+G Y E
Sbjct: 7605 LECTVAGTPE-LSTKWFKDGKELTSDNKYKISFFNKVSG--LKIINVAPSDSGVYSFEVQ 7661
Query: 317 NIVGKAHSDYMLYVYD 332
N VGK L V D
Sbjct: 7662 NPVGKDSCTASLQVSD 7677
Score = 52.4 bits (124), Expect = 8e-07
Identities = 59/284 (20%), Positives = 112/284 (39%), Gaps = 34/284 (11%)
Query: 52 VTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSL 111
V V G+ A++ CQ+ + P +++ L+ + ++F ++ +
Sbjct: 7970 VKVSVGDSASLQCQLAGT---------PEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVF 8020
Query: 112 TNVSISDEGRYFCQLYTDPPQESYTTITVL----VPP--RNLMIDIQKDTAVEGEEIEVN 165
V I+D G Y C+ + S +T + +PP + D+Q+ G + +
Sbjct: 8021 NQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETV---GLPVVFD 8077
Query: 166 CTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGV--PVICQVE 223
C S+P ++ W+K LK V+ T T L + K D + C
Sbjct: 8078 CAISGSEP-ISVSWYKDGKPLKDSPNVQTSFLDNTAT----LNIFKTDRSLAGQYSCTAT 8132
Query: 224 HPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRV 283
+P + + + L P P+ + G++ + C G QP+ V+W +
Sbjct: 8133 NPIGSASSSARLILTEGKNPPFFDIRLAPVDAVV--GESADFECHVTG-TQPIKVSWAKD 8189
Query: 284 DDEMPQHA------VLSGPNLFINNLNKTDNGTYRCEASNIVGK 321
E+ + + +L + ++K D+G Y C A N VGK
Sbjct: 8190 SREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGK 8233
Score = 49.3 bits (116), Expect = 6e-06
Identities = 61/266 (22%), Positives = 113/266 (42%), Gaps = 23/266 (8%)
Query: 98 QLLNFSSSELK--VSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDT 155
Q N +++E + + + ++ D G+Y C + ++S + +++ P + ++
Sbjct: 7912 QRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVK 7971
Query: 156 AVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDG 215
G+ + C +A P + W+KG+T+L+ + + V + + +V D G
Sbjct: 7972 VSVGDSASLQCQ-LAGTPEIGVSWYKGDTKLR-PTTTYKMHFRNNVATLVFNQVDINDSG 8029
Query: 216 VPVICQVEHPAVTGNLQTQRYLEVQYK--PQVHIQMTYPLQGLTREGDALELTCEAIGKP 273
IC+ E+ G + +L VQ + P + +Q G + C AI
Sbjct: 8030 -EYICKAENSV--GEVSASTFLTVQEQKLPPSFSRQLRDVQETV--GLPVVFDC-AISGS 8083
Query: 274 QPVMVTWVR-----VDDEMPQHAVLSGPNLFINNLNKTDN---GTYRCEASNIVGKAHSD 325
+P+ V+W + D Q + L N N+ KTD G Y C A+N +G A S
Sbjct: 8084 EPISVSWYKDGKPLKDSPNVQTSFLD--NTATLNIFKTDRSLAGQYSCTATNPIGSASSS 8141
Query: 326 YMLYVYDSRAGEEGSIR-AVDHAVIG 350
L + + + IR A AV+G
Sbjct: 8142 ARLILTEGKNPPFFDIRLAPVDAVVG 8167
Score = 48.9 bits (115), Expect = 8e-06
Identities = 46/243 (18%), Positives = 98/243 (40%), Gaps = 19/243 (7%)
Query: 100 LNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEG 159
++ S ++ L +V S G Y C + + + S TT + P + + + +G
Sbjct: 7823 VSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKG 7882
Query: 160 EEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKE--DDGVP 217
+ + + T P ++ W K + ++ T +L++ +D
Sbjct: 7883 KPLILEGT-FTGTPPISVTWKKNGINVTPSQRC----NITTTEKSAILEIPSSTVEDAGQ 7937
Query: 218 VICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVM 277
C +E+ + + Q + +P ++ P++ GD+ L C+ G P+ +
Sbjct: 7938 YNCYIENASGKDSCSAQILI---LEPPYFVKQLEPVK--VSVGDSASLQCQLAGTPE-IG 7991
Query: 278 VTWVRVDDEM------PQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVY 331
V+W + D ++ H + L N ++ D+G Y C+A N VG+ + L V
Sbjct: 7992 VSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQ 8051
Query: 332 DSR 334
+ +
Sbjct: 8052 EQK 8054
Score = 48.5 bits (114), Expect = 1e-05
Identities = 61/287 (21%), Positives = 114/287 (39%), Gaps = 33/287 (11%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
+DV G C ++ S+ + +++D +PLKDS +F + +
Sbjct: 8064 RDVQETVGLPVVFDCAISGSEPISVS---------WYKDGKPLKDSPNVQTSFLDNTATL 8114
Query: 110 SLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRN---LMIDIQKDTAVEGEEIEVNC 166
++ S G+Y C S + +L +N I + AV GE + C
Sbjct: 8115 NIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFEC 8174
Query: 167 TAMASKPATTIRWFKGNTELK--GKSEVEEWSDMYTVTSQLMLKVHKEDDG---VPVICQ 221
++P + W K + E++ GK ++ + +T +LKV K D G + +
Sbjct: 8175 HVTGTQP-IKVSWAKDSREIRSGGKYQISYLENSAHLT---VLKVDKGDSGQYTCYAVNE 8230
Query: 222 VEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWV 281
V + T L + L P +++ ++ EG++ +L G QP+ V W
Sbjct: 8231 VGKDSCTAQLNIKERL---IPPSFTKRLSETVE--ETEGNSFKLEGRVAGS-QPITVAWY 8284
Query: 282 R--VDDEMPQHAVLSGPN----LFINNLNKTDNGTYRCEASNIVGKA 322
+ ++ + + ++ N L + D G Y C+ SN G A
Sbjct: 8285 KNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSA 8331
Score = 48.1 bits (113), Expect = 1e-05
Identities = 67/293 (22%), Positives = 118/293 (40%), Gaps = 51/293 (17%)
Query: 65 QVNKSDDSVIQLL---NPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGR 121
QV D + ++ P + +++D RPL S+ ++F ++ ++ + + D G+
Sbjct: 4027 QVTAGDPATLEYTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQ 4086
Query: 122 YFCQLYTDPPQESY-TTITVL---------VPPRNLMIDIQKDTAVEGEEIEVNCTAMAS 171
Y ++ + S TT TVL P RN+ D+ V G ++C S
Sbjct: 4087 YTFEISNEVGSSSCETTFTVLDRDIAPFFTKPLRNV------DSVVNGT-CRLDCKIAGS 4139
Query: 172 KPATTIRWFKGNTELKGKSEVEEWSDMYTVT------SQLMLKVHKEDDGVPVICQVEHP 225
P + WFK E+ SD Y + S +++V D G C+ +
Sbjct: 4140 LPMR-VSWFKDGKEIAA-------SDRYRIAFVEGTASLEIIRVDMNDAG-NFTCRATNS 4190
Query: 226 AVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDD 285
G+ + L VQ P +T P G A+ L G P+ + W + +
Sbjct: 4191 V--GSKDSSGALIVQEPPSF---VTKPGSKDVLPGSAVCLKSTFQGST-PLTIRWFKGNK 4244
Query: 286 EM--------PQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYV 330
E+ + A+ S L++ + +D+GTY C+ SN+ G L+V
Sbjct: 4245 ELVSGGSCYITKEALESSLELYL--VKTSDSGTYTCKVSNVAGGVECSANLFV 4295
Score = 48.1 bits (113), Expect = 1e-05
Identities = 76/339 (22%), Positives = 137/339 (40%), Gaps = 38/339 (11%)
Query: 23 GLRLRLLLLLFSAAALIPTGDGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQ 82
G+R + L+ A+I G +TV GE T+ C+V + + ++
Sbjct: 5690 GMRENMATLMVLEPAVIVEKAGP------MTVTVGETCTLECKVAGTPELSVE------- 5736
Query: 83 TIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVL- 141
+++D + L S+ +F + + + +V D G Y Q+ + + S T + +
Sbjct: 5737 --WYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVS 5794
Query: 142 ---VPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDM 198
VPP + ++ V G + C S P + + WF T++ ++ +
Sbjct: 5795 DRAVPP-SFTRRLKNTGGVLGASCILECKVAGSSPIS-VAWFHEKTKIVSGAKYQTTFSD 5852
Query: 199 YTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTR 258
T QL + D G C + V G+ + + L VQ +P ++ PL+ L
Sbjct: 5853 NVCTLQLN-SLDSSDMG-NYTCVAAN--VAGSDECRAVLTVQ-EPPSFVKEPEPLEVLP- 5906
Query: 259 EGDALELTCEAIGKPQPVMVTWVRVDDEMPQ------HAVLSGPNLFINNLNKTDNGTYR 312
G + T G P P V W R E+ + + + L + N++ + +G Y
Sbjct: 5907 -GKNVTFTSVIRGTP-PFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYT 5964
Query: 313 CEASNIVGKAHSDYMLYVYDSRAGEEGSIRAVDHAVIGG 351
C SN G+A L+V + A + R DH+V G
Sbjct: 5965 CVVSNNAGQASCTTRLFVKEPAAFLK---RLSDHSVEPG 6000
Score = 47.8 bits (112), Expect = 2e-05
Identities = 48/229 (20%), Positives = 96/229 (41%), Gaps = 16/229 (6%)
Query: 100 LNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEG 159
+ F ++ + L+ + + +G+Y CQ D + + + + P + + +G
Sbjct: 4534 MTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSIDVTQG 4593
Query: 160 EEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVI 219
+ + +K T +WFK EL S+ + S TV+ ++ K+D G
Sbjct: 4594 DPATLQVKFSGTKEITA-KWFKDGQELTLGSKY-KISVTDTVSILKIISTEKKDSG-EYT 4650
Query: 220 CQVEHPAVTGNLQTQ-RYLEVQYKPQVHIQMTYPLQGL-TREGDALELTCEAIGKPQPVM 277
+V++ + + + L++ P T L+ + + +G ++L C G P+
Sbjct: 4651 FEVQNDVGRSSCKARINVLDLIIPP----SFTKKLKKMDSIKGSFIDLECIVAGS-HPIS 4705
Query: 278 VTWVRVDDEMPQHAVL------SGPNLFINNLNKTDNGTYRCEASNIVG 320
+ W + D E+ + L I+ L TD+GTY C A+N G
Sbjct: 4706 IQWFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAG 4754
Score = 47.8 bits (112), Expect = 2e-05
Identities = 51/250 (20%), Positives = 96/250 (38%), Gaps = 14/250 (5%)
Query: 78 NPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTT 137
+P + +D + L + ++F S + + +V GRY CQ + E
Sbjct: 5074 SPPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYA 5133
Query: 138 ITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSD 197
++ P ++ + E + + + C +A P ++W K ++ S S
Sbjct: 5134 FLLVQEPAQIVEKAKSVDVTEKDPMTLECV-VAGTPELKVKWLKDGKQIV-PSRYFSMSF 5191
Query: 198 MYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQ-RYLEVQYKPQVHIQMTYPLQGL 256
V S + V K+D G +VE+ + + R L+ P ++T + L
Sbjct: 5192 ENNVASFRIQSVMKQDSGQYTF-KVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVL 5250
Query: 257 TREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLS------GPNLFINNLNKTDNGT 310
G ++ + C+ G P+ W + E+ A +L +NNL D
Sbjct: 5251 ---GSSIHMECKVSGS-LPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTAN 5306
Query: 311 YRCEASNIVG 320
Y C+ SN+ G
Sbjct: 5307 YTCKVSNVAG 5316
Score = 47.0 bits (110), Expect = 3e-05
Identities = 65/293 (22%), Positives = 114/293 (38%), Gaps = 32/293 (10%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
K V V++ + C+V + + L NR+ ++ S+ L S +
Sbjct: 4962 KPVEVVKYSDVELECEVTGTPPFEVTWLKNNRE---------IRSSKKYTLTDRVSVFNL 5012
Query: 110 SLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAM 169
+T SD G Y C + + S +T L P + + I+ T V T +
Sbjct: 5013 HITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQST-V 5071
Query: 170 ASKPATTIRWFKGNTELKGKSEVEEWSDMYT--VTSQLMLKVHKEDDGVP--VICQVEHP 225
A P +I W LK ++E ++Y V S L++ D+G CQ ++
Sbjct: 5072 AGSPPISITW------LKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNE 5125
Query: 226 AVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDD 285
+G + +L VQ Q+ ++ + E D + L C G P+ + V W++
Sbjct: 5126 --SGVERCYAFLLVQEPAQI-VEKAKSVD--VTEKDPMTLECVVAGTPE-LKVKWLKDGK 5179
Query: 286 EMPQHAVLS------GPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYD 332
++ S + I ++ K D+G Y + N G + D L V D
Sbjct: 5180 QIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLD 5232
Score = 46.2 bits (108), Expect = 5e-05
Identities = 61/289 (21%), Positives = 124/289 (42%), Gaps = 35/289 (12%)
Query: 56 EGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVS 115
+GE + C+++ S P + +FR+ L +S ++F +S +++ S
Sbjct: 6378 QGESIQLECKISGS---------PEIKVSWFRNDSELHESWKYNMSFINSVALLTINEAS 6428
Query: 116 ISDEGRYFCQLYTDPPQESYTT-ITVLVPPRNLMIDIQKDT---AVEGEEIEVNCTAMAS 171
D G Y C+ + S +T +TV PP + QK + A++G ++ + C +
Sbjct: 6429 AEDSGDYICEAHNGVGDASCSTALTVKAPP----VFTQKPSPVGALKGSDVILQCEISGT 6484
Query: 172 KPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNL 231
P + W K +++ + + S + TS +L + D G C+ + G+
Sbjct: 6485 PPFEVV-WVKDRKQVRNSKKFKITSKHFD-TSLHILNLEASDVG-EYHCKATNE--VGSD 6539
Query: 232 QTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHA 291
++ + P+ +++ T GDA+EL G QP+ V W++ E+ + +
Sbjct: 6540 TCSCSVKFKEPPRFVKKLS---DTSTLIGDAVELRAIVEGF-QPISVVWLKDRGEVIRES 6595
Query: 292 VLSGPNLFINNL--------NKTDNGTYRCEASNIVGKAHSDYMLYVYD 332
+ + FI+N+ +++G Y C+ N G +L V +
Sbjct: 6596 ENTRIS-FIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLE 6643
Score = 45.1 bits (105), Expect = 1e-04
Identities = 36/137 (26%), Positives = 59/137 (43%), Gaps = 15/137 (10%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
+DVT+ EG+ T++CQ + PN ++ +FR+ R LK K+
Sbjct: 8752 QDVTLKEGQTCTMTCQFSV----------PNVKSEWFRNGRILKPQGRHKTEVEHKVHKL 8801
Query: 110 SLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAM 169
++ +V D+G+Y C+ Y D E+ + + P IQ E + C
Sbjct: 8802 TIADVRAEDQGQYTCK-YED--LETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECE-- 8856
Query: 170 ASKPATTIRWFKGNTEL 186
S + W+KG TEL
Sbjct: 8857 VSFDDAIVTWYKGPTEL 8873
Score = 44.7 bits (104), Expect = 2e-04
Identities = 59/278 (21%), Positives = 113/278 (40%), Gaps = 32/278 (11%)
Query: 57 GEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSI 116
G+ ++ CQV + + + + + RP + R F+++ + V+I
Sbjct: 6093 GDSVSLQCQVAGTPEITVSWYKGDTK------LRPTPEYRTY---FTNNVATLVFNKVNI 6143
Query: 117 SDEGRYFCQLYTDPPQESYTTITVL----VPPR--NLMIDIQKDTAVEGEEIEVNCTAMA 170
+D G Y C+ S T+ + +PP + DI++ G + + C
Sbjct: 6144 NDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTV---GLPVTLTCRLNG 6200
Query: 171 SKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGN 230
S P + W++ L+ ++ S + V + +L+ G C +P T +
Sbjct: 6201 SAPIQ-VCWYRDGVLLRDDENLQT-SFVDNVATLKILQTDLSHSG-QYSCSASNPLGTAS 6257
Query: 231 LQTQRYL-EVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQ 289
+ E + P I+ P+ G++ + C G QP+ +TW + + E+
Sbjct: 6258 SSARLTAREPKKSPFFDIK---PVSIDVIAGESADFECHVTGA-QPMRITWSKDNKEIRP 6313
Query: 290 HA------VLSGPNLFINNLNKTDNGTYRCEASNIVGK 321
V + P+L I + K D+G Y C+A+N VGK
Sbjct: 6314 GGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGK 6351
Score = 44.7 bits (104), Expect = 2e-04
Identities = 45/202 (22%), Positives = 79/202 (39%), Gaps = 22/202 (10%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
+D TV EGE AT C +L + ++F++ L SR L++ K+
Sbjct: 11581 EDQTVKEGETATFVC----------ELSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKL 11630
Query: 110 SLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAM 169
+ V++ D + Q+ S + VL + + TAVE +EI + C
Sbjct: 11631 EMKEVTLDDISQIKAQV---KELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVS 11687
Query: 170 ASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKED--DGVPVICQVEHPAV 227
P ++WFK E+ + +D + +LK+ K D D +C
Sbjct: 11688 KDVP---VKWFKDGEEIVPSPKYSIKAD----GLRRILKIKKADLKDKGEYVCDCGTDKT 11740
Query: 228 TGNLQTQRYLEVQYKPQVHIQM 249
N+ + L KP +++
Sbjct: 11741 KANVTVEARLIKVEKPLYGVEV 11762
Score = 43.1 bits (100), Expect = 5e-04
Identities = 67/293 (22%), Positives = 110/293 (37%), Gaps = 39/293 (13%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
KDVTV GE AT C+++ D V L + L+ S + +
Sbjct: 12203 KDVTVTAGETATFDCELSYEDIPVEWYLKGKK----------LEPSDKVVPRSEGKVHTL 12252
Query: 110 SLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAM 169
+L +V + D G QL T +++ + V PP ++ T EG + C
Sbjct: 12253 TLRDVKLEDAGE--VQL-TAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECE-- 12307
Query: 170 ASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTG 229
S+ ++WFK TE+ + E +D +L++ +D C + +
Sbjct: 12308 VSRENAKVKWFKNGTEILKSKKYEIVAD--GRVRKLVIHDCTPEDIKTYTCDAKDFKTSC 12365
Query: 230 NLQTQRYLEVQYKPQVHIQMTYPLQGL-TREGDALELTCEAIGKPQPVMVTWVRVDDEM- 287
NL H++ PL L RE + CE + V W + E+
Sbjct: 12366 NLNV---------VPPHVEFLRPLTDLQVREKEMARFECEL--SRENAKVKWFKDGAEIK 12414
Query: 288 --PQHAVLSGPNLFINNLNK---TDNGTYRCEASNIVGKAHSDYMLYVYDSRA 335
++ ++S + I +NK D Y CE V A + ML V + A
Sbjct: 12415 KGKKYDIISKGAVRILVINKCLLDDEAEYSCE----VRTARTSGMLTVLEEEA 12463
Score = 42.7 bits (99), Expect = 6e-04
Identities = 24/80 (30%), Positives = 40/80 (50%), Gaps = 5/80 (6%)
Query: 258 REGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPN----LFINNLNKTDNGTYRC 313
R G +L L G+P PV +TW + ++ A++ L ++ +N+ D G Y
Sbjct: 29459 RAGASLRLMVSVSGRPPPV-ITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTI 29517
Query: 314 EASNIVGKAHSDYMLYVYDS 333
EA N GK + ++ VYD+
Sbjct: 29518 EAENQSGKKSATVLVKVYDT 29537
Score = 42.0 bits (97), Expect = 0.001
Identities = 65/295 (22%), Positives = 110/295 (37%), Gaps = 40/295 (13%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
+D EG+ A C+V+ +D V + Y +D + +K SRF + ++
Sbjct: 3352 QDTVTSEGQPARFQCRVSGTDLKV---------SWYSKD-KKIKPSRFFRMTQFEDTYQL 3401
Query: 110 SLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMID-IQKDTAVEG--------- 159
+ DEG Y Q S T L P +++ + I+++ +E
Sbjct: 3402 EIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRK 3461
Query: 160 -EEIEVNCTAMA-------SKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHK 211
E +EV +A S P +WFK E+ + S Y ++S +L+
Sbjct: 3462 IEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKY-ISSLEILRTQV 3520
Query: 212 EDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIG 271
D G C+ + + + + Y P ++ P T G A + C G
Sbjct: 3521 VDCG-EYTCKASNEYGSVSCTATLTVTEAYPPTF---LSRPKSLTTFVGKAAKFICTVTG 3576
Query: 272 KPQPVMVTWVRVDDEM---PQHAVLSGPN---LFINNLNKTDNGTYRCEASNIVG 320
P + W + + P + N L ++NL D G Y C+ASN G
Sbjct: 3577 TPV-IETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFG 3630
Score = 42.0 bits (97), Expect = 0.001
Identities = 30/103 (29%), Positives = 52/103 (50%), Gaps = 9/103 (8%)
Query: 237 LEVQYKPQVHIQMTYPLQGLT-REGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSG 295
++ Q P++ + + L GLT + G +EL GKP+P +TW + D + Q ++
Sbjct: 13682 VDTQEAPEIFLDVKL-LAGLTVKAGTKIELPATVTGKPEP-KITWTKADMILKQDKRITI 13739
Query: 296 PNL------FINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYD 332
N+ I + ++D GTY EA N+ G+A + + V D
Sbjct: 13740 ENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLD 13782
Score = 42.0 bits (97), Expect = 0.001
Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 7/106 (6%)
Query: 243 PQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQ------HAVLSGP 296
P++ ++ Y + + GD +++ +G+P+P VTW + D + Q +
Sbjct: 21063 PELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPT-VTWKKGDQILKQTQRVNFETTATST 21121
Query: 297 NLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDSRAGEEGSIR 342
L IN ++D+G Y A NIVG+ + V+D G I+
Sbjct: 21122 ILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIK 21167
Score = 41.6 bits (96), Expect = 0.001
Identities = 54/256 (21%), Positives = 99/256 (38%), Gaps = 23/256 (8%)
Query: 85 YFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPP 144
+F+ R L ++ ++ L V + G Y C + D S TT + P
Sbjct: 6867 WFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEP 6926
Query: 145 RNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQ 204
+ + + G I + T + P + + W K + S+ E S T S
Sbjct: 6927 ATFVKRLADFSVETGSPIVLEATYTGTPPIS-VSWIKDEYLI---SQSERCSITMTEKST 6982
Query: 205 LMLKVHKE-DDGVPVICQVEHPAVTGNLQTQ-RYLEVQY--KPQVHIQMTYPLQGLTREG 260
++ + +D C +E+ A + LE Y +P H++ G
Sbjct: 6983 ILEILESTIEDYAQYSCLIENEAGQDICEALVSVLEPPYFIEPLEHVEAVI--------G 7034
Query: 261 DALELTCEAIGKPQPVMVTWVRVDDEM---PQHAVLSGPN---LFINNLNKTDNGTYRCE 314
+ L C+ G P+ + ++W + ++ P + + N L IN ++ +D G Y C+
Sbjct: 7035 EPATLQCKVDGTPE-IRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCK 7093
Query: 315 ASNIVGKAHSDYMLYV 330
A N VG S +L +
Sbjct: 7094 ADNSVGAVASSAVLVI 7109
Score = 41.6 bits (96), Expect = 0.001
Identities = 37/171 (21%), Positives = 69/171 (40%), Gaps = 11/171 (6%)
Query: 174 ATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQT 233
A + FK +E++ S V E T T + + +E ++ T
Sbjct: 32493 AYAVSSFKKTSEMEASSSVREVKSQMTETRESLSSYEHSASAEMKSAALEEKSLEEK-ST 32551
Query: 234 QRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVR---VDDEMPQH 290
R ++ ++ +T P EG++ +C+ G+P P VTW+R V +H
Sbjct: 32552 TRKIKTTLAARI---LTKPRSMTVYEGESARFSCDTDGEPVPT-VTWLRKGQVLSTSARH 32607
Query: 291 AVLS---GPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDSRAGEE 338
V + I+++ +D G Y N GK +++ L + +R E+
Sbjct: 32608 QVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQKARVTEK 32658
Score = 39.3 bits (90), Expect = 0.007
Identities = 49/262 (18%), Positives = 99/262 (37%), Gaps = 16/262 (6%)
Query: 78 NPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTT 137
+P + ++FR+ L S + F S + + N+S D G + C+ S +T
Sbjct: 5450 SPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCST 5509
Query: 138 ITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSD 197
++ P ++ E+ + C ++ P + W+K +L+ + + S
Sbjct: 5510 KVIVKEPPVFSSFPPIVETLKNAEVSLEC-ELSGTPPFEVVWYKDKRQLRSSKKYKIASK 5568
Query: 198 MYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLT 257
+ TS +L V D G C+ ++ + L+ +P + L +
Sbjct: 5569 NFH-TSIHILNVDTSDIG-EYHCKAQNEVGSDTCVCTVKLK---EPPRFVSKLNSLTVVA 5623
Query: 258 REGDALELTCEAIGKPQPVMVTWVRVDDEMPQHA-------VLSGPNLFINNLNKTDNGT 310
E L+ + E QP+ V W++ +E+ + + V + L + G
Sbjct: 5624 GEPAELQASIEG---AQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGK 5680
Query: 311 YRCEASNIVGKAHSDYMLYVYD 332
Y C+ N G + L V +
Sbjct: 5681 YICQIKNDGGMRENMATLMVLE 5702
Score = 38.9 bits (89), Expect = 0.009
Identities = 25/93 (26%), Positives = 42/93 (45%), Gaps = 7/93 (7%)
Query: 256 LTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHA------VLSGPNLFINNLNKTDNG 309
+ + G++L + G+P P VTW + E+ + VL +LF+ + + G
Sbjct: 27969 IIKSGESLRIKALVQGRPVP-RVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG 28027
Query: 310 TYRCEASNIVGKAHSDYMLYVYDSRAGEEGSIR 342
Y EA N G A ++ + V D+ G IR
Sbjct: 28028 VYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIR 28060
Score = 38.1 bits (87), Expect = 0.015
Identities = 31/115 (26%), Positives = 51/115 (44%), Gaps = 8/115 (6%)
Query: 223 EHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVR 282
EH V G + + LE P + + + R G +L L G+P P V W +
Sbjct: 22923 EHADVPGPIIVEEKLEA---PDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPE-VKWGK 22978
Query: 283 VDDEMPQHAVL----SGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDS 333
VD E+ A++ S +L ++N+N+ D+G Y N G + + V D+
Sbjct: 22979 VDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDT 23033
Score = 37.4 bits (85), Expect = 0.025
Identities = 35/146 (23%), Positives = 56/146 (38%), Gaps = 25/146 (17%)
Query: 52 VTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSL 111
VTV EGE +SC V S+ IQ L R+ +K S +F+S + L
Sbjct: 8355 VTVSEGEYVQLSCHVQGSEPIRIQWLKAGRE---------IKPSDRCSFSFASGTAVLEL 8405
Query: 112 TNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVN------ 165
+V+ +D G Y C+ ++ T V + + + K AV+G V+
Sbjct: 8406 RDVAKADSGDYVCKA-SNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQSIR 8464
Query: 166 ---------CTAMASKPATTIRWFKG 182
+ P ++W KG
Sbjct: 8465 VVEKTTATFIAKVGGDPIPNVKWTKG 8490
Score = 37.0 bits (84), Expect = 0.033
Identities = 57/271 (21%), Positives = 106/271 (39%), Gaps = 41/271 (15%)
Query: 51 DVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSR-FQLLNFSSSELKV 109
D+ V E E+A C++++ N + +F+D +K + + +++ + + V
Sbjct: 12382 DLQVREKEMARFECELSRE----------NAKVKWFKDGAEIKKGKKYDIISKGAVRILV 12431
Query: 110 SLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAM 169
+ + DE Y C++ T + +TVL ++ E + I++ C
Sbjct: 12432 -INKCLLDDEAEYSCEVRT---ARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEV- 12486
Query: 170 ASKPATTIRWFKGNTEL--KGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAV 227
SKP + W+KG+ E+ G+ E+ + Q H ED G C++
Sbjct: 12487 -SKPGAEVIWYKGDEEIIETGRYEILTEGRKRILVIQ---NAHLEDAG-NYNCRLPSSRT 12541
Query: 228 TGNLQTQRY-LEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDE 286
G ++ E KPQ ++++ EG+ E C + PV W R D
Sbjct: 12542 DGKVKVHELAAEFISKPQ-NLEIL--------EGEKAEFVCSISKESFPVQ--WKRDDKT 12590
Query: 287 MPQ----HAVLSGPN--LFINNLNKTDNGTY 311
+ + G L + + D GTY
Sbjct: 12591 LESGDKYDVIADGKKRVLVVKDATLQDMGTY 12621
Score = 36.6 bits (83), Expect = 0.043
Identities = 22/78 (28%), Positives = 37/78 (47%), Gaps = 7/78 (8%)
Query: 257 TREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPN------LFINNLNKTDNGT 310
T+ G+A +L+C+ +G+P P + W R E+ Q + L + + D G
Sbjct: 30544 TKLGEAAQLSCQIVGRPLP-DIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGV 30602
Query: 311 YRCEASNIVGKAHSDYML 328
Y C A+N VG+ + L
Sbjct: 30603 YTCIATNEVGEVETSSKL 30620
Score = 36.6 bits (83), Expect = 0.043
Identities = 56/293 (19%), Positives = 110/293 (37%), Gaps = 37/293 (12%)
Query: 56 EGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVS 115
EG+ +C+++ P+ + +F++ P+ S ++ S + + + N S
Sbjct: 33147 EGQNVLFTCEISGE---------PSPEIEWFKNNLPISISSNVSISRSRNVYSLEIRNAS 33197
Query: 116 ISDEGRYFCQLYTDPPQESYTTITVLV-----PPRNLMIDIQKDTAVEGEEIEVNCTAMA 170
+SD G+Y + Q S T +++ P R +++ DT+++G + A
Sbjct: 33198 VSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSVQMSA 33257
Query: 171 SKPATTIRWFKGN-----TELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHP 225
SK + F + TE+K S + M ++ + G+ + Q+E
Sbjct: 33258 SKQEASFSSFSSSSASSMTEMKFASMSAQ--SMSSMQESFVEMSSSSFMGISNMTQLES- 33314
Query: 226 AVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTW----- 280
T + L+ + P EG L + C G+P P VTW
Sbjct: 33315 ------STSKMLKAGIRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTP-EVTWSCGGR 33367
Query: 281 -VRVDDEMPQHAVLSG--PNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYV 330
+ ++ H + L I ++ K D G Y N G + +++
Sbjct: 33368 KIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 33420
Score = 36.2 bits (82), Expect = 0.056
Identities = 24/89 (26%), Positives = 37/89 (41%), Gaps = 7/89 (7%)
Query: 260 GDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPN------LFINNLNKTDNGTYRC 313
G+ L + GKP P + W+R D E+ + A N L + + + D G Y
Sbjct: 23640 GETFRLEADVHGKPLPT-IEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYIL 23698
Query: 314 EASNIVGKAHSDYMLYVYDSRAGEEGSIR 342
ASN+ G + V D EG ++
Sbjct: 23699 RASNVAGSKSFPVNVKVLDRPGPPEGPVQ 23727
Score = 35.8 bits (81), Expect = 0.073
Identities = 26/68 (38%), Positives = 34/68 (50%), Gaps = 6/68 (8%)
Query: 131 PQESYTTITV---LVPPRNLMIDIQKDTAV--EGEEIEVNCTAMASKPATTIRWFKGNTE 185
P ES IT + PPR M KDT V GE +V+ + KP TI+W KG+ E
Sbjct: 22525 PSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDAD-IYGKPIPTIQWIKGDQE 22583
Query: 186 LKGKSEVE 193
L + +E
Sbjct: 22584 LSNTARLE 22591
Score = 35.8 bits (81), Expect = 0.073
Identities = 30/124 (24%), Positives = 52/124 (41%), Gaps = 18/124 (14%)
Query: 225 PAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVD 284
P + +L Q L++ + TY +Q G+ L++ IG+P+P ++WV+
Sbjct: 24302 PVIAKDLTIQPSLKLPFN-------TYSIQA----GEDLKIEIPVIGRPRP-NISWVKDG 24349
Query: 285 DEMPQ------HAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDSRAGEE 338
+ + Q + L I NK D G Y A+N G A + + V +
Sbjct: 24350 EPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPV 24409
Query: 339 GSIR 342
G +R
Sbjct: 24410 GPVR 24413
Score = 35.4 bits (80), Expect = 0.096
Identities = 61/292 (20%), Positives = 107/292 (36%), Gaps = 35/292 (11%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
K+V VIE + A + +VN+ D + ++ + FQ+ ++
Sbjct: 3154 KEVQVIEKQRAVVEFEVNEDD-------------VDAHWYKDGIEINFQVQERHKYVVER 3200
Query: 110 SLTNVSISDEGRYFCQLYTDPPQESYTTITVLV---PPRNLMIDIQKDTAVEGEEIEVNC 166
+ + IS+ + YT + +++T+ V P ++ ++Q T G+ C
Sbjct: 3201 RIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARF-C 3259
Query: 167 TAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPA 226
++ +P I W+K L + + D T L+++ ED V C+ ++
Sbjct: 3260 AVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYT-LLLIEAFPEDAAV-YTCEAKNDY 3317
Query: 227 VTGNLQTQRYLEV-------QYKPQVHIQMTYPLQG-LTREGDALELTCEAIGKPQPVMV 278
+EV Q P + PLQ +T EG C G + V
Sbjct: 3318 GVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSG--TDLKV 3375
Query: 279 TWVRVDDEMPQHAVL------SGPNLFINNLNKTDNGTYRCEASNIVGKAHS 324
+W D ++ L I D GTY ASN VG+ S
Sbjct: 3376 SWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSS 3427
Score = 35.4 bits (80), Expect = 0.096
Identities = 25/108 (23%), Positives = 50/108 (46%), Gaps = 13/108 (12%)
Query: 25 RLRLLLLLFSAAALIPTGDGQNLFT---KDVTVIEGEVATISCQVNKSDDSVIQLLNPNR 81
++R+ + S+ A + +G FT +D T +E + + C+++K+D V
Sbjct: 11997 QIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAPVK------- 12049
Query: 82 QTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTD 129
+F+D + +K S+ ++ + + L SD G+Y C TD
Sbjct: 12050 ---WFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTCDCGTD 12094
Score = 35.4 bits (80), Expect = 0.096
Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 6/84 (7%)
Query: 253 LQGLTREGDALELTCEAIGKPQPVMVTW---VRVDDEMPQHAVLSGPN---LFINNLNKT 306
+ + EG ++ C+ Q VTW VR + ++ + L++ ++ K
Sbjct: 31575 MHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKL 31634
Query: 307 DNGTYRCEASNIVGKAHSDYMLYV 330
D+GTYRC+ N G+ S L+V
Sbjct: 31635 DDGTYRCKVVNDYGEDSSYAELFV 31658
Score = 35.0 bits (79), Expect = 0.12
Identities = 25/109 (22%), Positives = 45/109 (41%), Gaps = 7/109 (6%)
Query: 243 PQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLS------GP 296
P++ + + + + + G+A L + G+P P M W + E+ A L
Sbjct: 21459 PKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTM-EWSKDGKELEGTAKLEIKIADFST 21517
Query: 297 NLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDSRAGEEGSIRAVD 345
NL + + D+G Y A+N G A + + V D EG + +
Sbjct: 21518 NLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTE 21566
Score = 35.0 bits (79), Expect = 0.12
Identities = 31/127 (24%), Positives = 49/127 (38%), Gaps = 8/127 (6%)
Query: 223 EHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVR 282
E V G ++ LE P + Y R+G + LT GKP P+ W +
Sbjct: 30117 EPAEVPGTVKVTEMLEY---PDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPI-CKWTK 30172
Query: 283 VDDEMPQHAVL----SGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDSRAGEE 338
++ + A++ + L I ++ D+GTY N GK + V S E
Sbjct: 30173 EGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPE 30232
Query: 339 GSIRAVD 345
G + D
Sbjct: 30233 GPLEYDD 30239
Score = 34.7 bits (78), Expect = 0.16
Identities = 45/199 (22%), Positives = 74/199 (37%), Gaps = 29/199 (14%)
Query: 171 SKPATTIRW----FKGNTELKG------KSEVEEWSDM---------YTVTSQLMLKVHK 211
SK ++ W F G E+ G K+++ +W + YTVT + +K
Sbjct: 28266 SKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYK 28325
Query: 212 -EDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAI 270
+ + + VTG ++ L P++ I + + R G ++ L
Sbjct: 28326 FRVSAINGAGKGDSCEVTGTIKAVDRLTA---PELDIDANFKQTHVVRAGASIRLFIAYQ 28382
Query: 271 GKPQPVMVTWVRVDDEMPQ----HAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDY 326
G+P P V W + D + H S L + N N+ D G Y N G +
Sbjct: 28383 GRPTPTAV-WSKPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITF 28441
Query: 327 MLYVYDSRAGEEGSIRAVD 345
+ V D+ G G I D
Sbjct: 28442 TVKVLDT-PGPPGPITFKD 28459
Score = 34.3 bits (77), Expect = 0.21
Identities = 49/260 (18%), Positives = 98/260 (37%), Gaps = 15/260 (5%)
Query: 79 PNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTI 138
P + +F+D L+ R + + + +D G Y C++ + +
Sbjct: 4420 PPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSAR 4479
Query: 139 TVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDM 198
L P + + I+ +++ G T S P T + W K + E+ + +
Sbjct: 4480 VTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPIT-VTWLKDSDEITEDDNIRMTFEN 4538
Query: 199 YTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTR 258
V S + + + DG +CQ ++ A G + L V+ +P + +
Sbjct: 4539 -NVASLYLSGIEVKHDG-KYVCQAKNDA--GIQRCSALLSVK-EPATITEEAVSID--VT 4591
Query: 259 EGDALELTCEAIGKPQPVMVTWVRVDDEMP-----QHAVLSGPNLF-INNLNKTDNGTYR 312
+GD L + G + + W + E+ + +V ++ I + K D+G Y
Sbjct: 4592 QGDPATLQVKFSGTKE-ITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYT 4650
Query: 313 CEASNIVGKAHSDYMLYVYD 332
E N VG++ + V D
Sbjct: 4651 FEVQNDVGRSSCKARINVLD 4670
Score = 34.3 bits (77), Expect = 0.21
Identities = 32/138 (23%), Positives = 57/138 (41%), Gaps = 15/138 (10%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
KDVT E E A + ++L + N + +F++ + L +R + +
Sbjct: 11936 KDVTAKEKESAVFT----------VELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSI 11985
Query: 110 SLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAM 169
+ ++SI D + + S +TVL +Q T VE +E+ + C
Sbjct: 11986 TFKDLSIDDTSQIRVEAMG---MSSEAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEI- 12041
Query: 170 ASKPATTIRWFKGNTELK 187
SK ++WFK E+K
Sbjct: 12042 -SKADAPVKWFKDGKEIK 12058
Score = 33.9 bits (76), Expect = 0.28
Identities = 27/86 (31%), Positives = 36/86 (41%), Gaps = 7/86 (8%)
Query: 259 EGDALELTCEAIGKPQPVMVTWVRVDDEMP-----QHAVLSG-PNLFINNLNKTDNGTYR 312
EG+++ L C G P P VTW R D ++ Q SG L I D+G +
Sbjct: 956 EGESVTLECHISGYPSPT-VTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFT 1014
Query: 313 CEASNIVGKAHSDYMLYVYDSRAGEE 338
C A N G + L V S E+
Sbjct: 1015 CSAVNEAGTVSTSCYLAVQVSEEFEK 1040
Score = 33.5 bits (75), Expect = 0.36
Identities = 21/75 (28%), Positives = 33/75 (44%), Gaps = 9/75 (12%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
K+VTVIEGE T+ C ++ + T Y D++ FQ + F S ++
Sbjct: 950 KNVTVIEGESVTLECHISGYPSPTV--------TWYREDYQIESSIDFQ-ITFQSGIARL 1000
Query: 110 SLTNVSISDEGRYFC 124
+ D GR+ C
Sbjct: 1001 MIREAFAEDSGRFTC 1015
Score = 33.5 bits (75), Expect = 0.36
Identities = 46/234 (19%), Positives = 89/234 (38%), Gaps = 20/234 (8%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
KDV I G + C+V+ S + +F+D + +FS + +
Sbjct: 6748 KDVNAILGASVVLECRVSGSAPISVG---------WFQDGNEIVSGPKCQSSFSENVCTL 6798
Query: 110 SLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAM 169
+L+ + SD G Y C + + + + P + + G + + +
Sbjct: 6799 NLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFT-SVI 6857
Query: 170 ASKPATTIRWFKGNTEL-KGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVT 228
P ++WFKG+ EL G+S D VT + +V + G C V + A +
Sbjct: 6858 RGTPPFKVKWFKGSRELVPGESCNISLEDF--VTELELFEVQPLESG-DYSCLVTNDAGS 6914
Query: 229 GNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVR 282
+ T +++ +P ++ G + L G P P+ V+W++
Sbjct: 6915 ASCTTHLFVK---EPATFVKRLADFS--VETGSPIVLEATYTGTP-PISVSWIK 6962
Score = 33.1 bits (74), Expect = 0.47
Identities = 31/123 (25%), Positives = 56/123 (45%), Gaps = 14/123 (11%)
Query: 83 TIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYT-------DPPQESY 135
T Y + R L + R+ NFS+ L+ T ++++ Y ++ PP E
Sbjct: 21389 TSYIVEKRDLPNGRWLKANFSNI-LENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPS 21447
Query: 136 TTITVL--VPPRNLMIDIQ-KDTAV--EGEEIEVNCTAMASKPATTIRWFKGNTELKGKS 190
IT V + +D++ KDT + GE + ++ +P T+ W K EL+G +
Sbjct: 21448 DAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEAD-VSGRPPPTMEWSKDGKELEGTA 21506
Query: 191 EVE 193
++E
Sbjct: 21507 KLE 21509
Score = 33.1 bits (74), Expect = 0.47
Identities = 21/82 (25%), Positives = 38/82 (46%), Gaps = 5/82 (6%)
Query: 256 LTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVL----SGPNLFINNLNKTDNGTY 311
+ + G + +T G+P P V W + D ++ A + S +L I N N+ D+G Y
Sbjct: 26197 IVKAGASFTMTVPFRGRPVP-NVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKY 26255
Query: 312 RCEASNIVGKAHSDYMLYVYDS 333
N++ A ++ V D+
Sbjct: 26256 TLTIQNVLSAASLTLVVKVLDT 26277
Score = 33.1 bits (74), Expect = 0.47
Identities = 33/163 (20%), Positives = 59/163 (36%), Gaps = 10/163 (6%)
Query: 174 ATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQT 233
AT ++W EL E T + H+++ + I + + V
Sbjct: 33065 ATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKEGIVKCQYDL 33124
Query: 234 QRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTW------VRVDDEM 287
E+ P ++ P EG + TCE G+P P + W + + +
Sbjct: 33125 TLSKELSDAPAF---ISQPRSQNINEGQNVLFTCEISGEPSP-EIEWFKNNLPISISSNV 33180
Query: 288 PQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYV 330
+ +L I N + +D+G Y +A N G+ + L V
Sbjct: 33181 SISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 33223
Score = 32.3 bits (72), Expect = 0.81
Identities = 67/277 (24%), Positives = 106/277 (38%), Gaps = 32/277 (11%)
Query: 57 GEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSI 116
G +A +C++ + + Q R+ IY D ++ S++ S L++ T V
Sbjct: 3470 GHLAKFTCEIQSAPNVRFQWFKAGRE-IYESDKCSIRSSKY------ISSLEILRTQVV- 3521
Query: 117 SDEGRYFCQLYTDPPQESYT---TITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKP 173
D G Y C+ + S T T+T PP L T V G+ + CT +
Sbjct: 3522 -DCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFV-GKAAKFICTVTGTPV 3579
Query: 174 ATTIRWFKGNTELKGKSEVEEW--SDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNL 231
TI W K L S W SD + + +D GV C+ +
Sbjct: 3580 IETI-WQKDGAAL---SPSPNWRISDAENKHILELSNLTIQDRGV-YSCKASNKFGADIC 3634
Query: 232 QTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHA 291
Q + L + KP I+ P+Q + + L C+ + + + V VTW + ++P
Sbjct: 3635 QAE--LIIIDKPHF-IKELEPVQSAINK--KVHLECQ-VDEDRKVTVTWSKDGQKLPPGK 3688
Query: 292 VLSG------PNLFINNLNKTDNGTYRCEASNIVGKA 322
L I D+GTY C ASN G +
Sbjct: 3689 DYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSS 3725
Score = 32.0 bits (71), Expect = 1.1
Identities = 38/168 (22%), Positives = 71/168 (42%), Gaps = 21/168 (12%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
KDV VIEG A + C+V+ D + ++ Y D + D R Q + ++ ++
Sbjct: 2452 KDVNVIEGTKAVLECKVSVPDVTSVKW--------YLNDEQIKPDDRVQAI-VKGTKQRL 2502
Query: 110 SLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAM 169
+ SDEG Y +L + T + V ++ ++ T E + +
Sbjct: 2503 VINRTHASDEGPY--KLIVGRVE---TNCNLSVEKIKIIRGLRDLTCTETQNVVFE--VE 2555
Query: 170 ASKPATTIRWFKGNTELK--GKSEVEEWSDMYTVTSQLMLKVHKEDDG 215
S + W + E+K K ++E +Y +T +L + K+D+G
Sbjct: 2556 LSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLT---VLNMMKDDEG 2600
Score = 32.0 bits (71), Expect = 1.1
Identities = 17/70 (24%), Positives = 40/70 (57%), Gaps = 8/70 (11%)
Query: 58 EVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDS-RFQLLNFSSSELKVSLTNVSI 116
E+A ++C V + SV++ ++ +++D + LK++ FQ + ++ + N++
Sbjct: 32731 EIAKLTCVV---ESSVLRA----KEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTE 32783
Query: 117 SDEGRYFCQL 126
SD+G Y C++
Sbjct: 32784 SDQGEYVCEI 32793
Score = 31.6 bits (70), Expect = 1.4
Identities = 30/161 (18%), Positives = 75/161 (46%), Gaps = 15/161 (9%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELK- 108
++VTV++G+ +SC++NK R ++ +D + + + +++ ++
Sbjct: 11220 EEVTVVKGQPLYLSCELNK-----------ERDVVWRKDGKIVVEKPGRIVPGVIGLMRA 11268
Query: 109 VSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTA 168
+++ + +D G Y + E + + V+ R+ ++ +D V+ + +
Sbjct: 11269 LTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFACD 11328
Query: 169 MASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKV 209
+A K I+WFKG E+ +E + +++ + L LK+
Sbjct: 11329 IA-KDTPNIKWFKGYDEI--PAEPNDKTEILRDGNHLYLKI 11366
Score = 31.6 bits (70), Expect = 1.4
Identities = 48/204 (23%), Positives = 78/204 (38%), Gaps = 30/204 (14%)
Query: 50 KDVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV 109
KDVT GE A +SCQ+ I+ ++ I R ++ D R L + E +
Sbjct: 30540 KDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQE- 30598
Query: 110 SLTNVSISDEGRYFCQLYTDPPQESYTTITVLV-------PPRNLMIDIQKDTAVEGEEI 162
DEG Y C + T+ E T+ +L+ P L +K G +
Sbjct: 30599 --------DEGVYTC-IATNEVGEVETSSKLLLQATPQFHPGYPLK---EKYYGAVGSTL 30646
Query: 163 EVNCTAMASKPATTIRWFKGNTELKGKSEVE-EWSDMYT--VTSQLMLKVHKEDDGVPVI 219
++ +P + WF G L+ + E ++ YT V + K H
Sbjct: 30647 RLH-VMYIGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAGK------ 30699
Query: 220 CQVEHPAVTGNLQTQRYLEVQYKP 243
+V+ V G + +E+Q KP
Sbjct: 30700 YKVQLSNVFGTVDAILDVEIQDKP 30723
Score = 30.4 bits (67), Expect = 3.1
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 10/86 (11%)
Query: 253 LQGLT-REGDALELTCEAIGKPQPVMVTW-------VRVDDEMPQHAVLSGPNLFINNLN 304
LQ +T R+G + L G P PV+ + +D ++ Q L +L I
Sbjct: 110 LQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLY--SLLIAEAY 167
Query: 305 KTDNGTYRCEASNIVGKAHSDYMLYV 330
D+GTY A+N VG+A S L V
Sbjct: 168 PEDSGTYSVNATNSVGRATSTAELLV 193
Score = 30.0 bits (66), Expect = 4.0
Identities = 19/86 (22%), Positives = 42/86 (48%), Gaps = 2/86 (2%)
Query: 83 TIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVL- 141
T + +D +++S + K+ + +V +SD G Y C L +++ T V+
Sbjct: 11149 TTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVE 11208
Query: 142 -VPPRNLMIDIQKDTAVEGEEIEVNC 166
+P R + ++ T V+G+ + ++C
Sbjct: 11209 ELPVRFVKTLEEEVTVVKGQPLYLSC 11234
Score = 30.0 bits (66), Expect = 4.0
Identities = 19/84 (22%), Positives = 41/84 (48%), Gaps = 7/84 (8%)
Query: 243 PQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHA---VLSGPN-- 297
P+V + + + + + G+ L++ + G+P PV ++W + E+ + A ++S N
Sbjct: 25787 PRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPV-ISWAKDGIEIEERARTEIISTDNHT 25845
Query: 298 -LFINNLNKTDNGTYRCEASNIVG 320
L + + + D G Y N+ G
Sbjct: 25846 LLTVKDCIRRDTGQYVLTLKNVAG 25869
Score = 29.6 bits (65), Expect = 5.2
Identities = 24/107 (22%), Positives = 41/107 (38%), Gaps = 8/107 (7%)
Query: 243 PQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAV-------LSG 295
P + Y + G+ L + GKP P +V W + E+ + A +
Sbjct: 24705 PNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVV-WSKDGKELEETAARMEIKSTIQK 24763
Query: 296 PNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDSRAGEEGSIR 342
L + + +TD G Y + SN+ G + V D EG ++
Sbjct: 24764 TTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLK 24810
Score = 29.6 bits (65), Expect = 5.2
Identities = 53/277 (19%), Positives = 93/277 (33%), Gaps = 47/277 (16%)
Query: 84 IYFRDFRPLKDSRFQ---LLNFSSSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITV 140
+Y +D L D ++ + ++ L + + Y+C+ + T+ +
Sbjct: 31626 LYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRL 31685
Query: 141 LVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELK-GKSEVEEWSDMY 199
L P + + TA GE + T + P + W+K ++K G ++ + +
Sbjct: 31686 LERPPEFTLPLYNKTAYVGENVRFGVT-ITVHPEPHVTWYKSGQKIKPGDNDKKYTFESD 31744
Query: 200 TVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLT-- 257
QL + DD E+ V N +Y E K ++ + + P T
Sbjct: 31745 KGLYQLTINSVTTDD------DAEYTVVARN----KYGEDSCKAKLTVTLHPPPTDSTLR 31794
Query: 258 ------------REGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPN-------- 297
+EG ++ G P P + W E + GPN
Sbjct: 31795 PMFKRLLANAECQEGQSVCFEIRVSGIPPPTL-KW-----EKDGQPLSLGPNIEIIHEGL 31848
Query: 298 ----LFINNLNKTDNGTYRCEASNIVGKAHSDYMLYV 330
L I + D G YR A+N G L V
Sbjct: 31849 DYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQV 31885
Score = 29.3 bits (64), Expect = 6.9
Identities = 22/94 (23%), Positives = 38/94 (40%), Gaps = 11/94 (11%)
Query: 260 GDALELTCEAIGKPQPVMVTWVRVDDEMPQHAV--------LSGPNLFINNLNKTDNGTY 311
G L++ G+P+P +TW + D +P L L I +K D G Y
Sbjct: 23244 GQDLKIEVPISGRPKPT-ITWTK--DGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 23300
Query: 312 RCEASNIVGKAHSDYMLYVYDSRAGEEGSIRAVD 345
+N+VG+ + + D +G ++ D
Sbjct: 23301 GITVANVVGQKTASIEIVTLDKPDPPKGPVKFDD 23334
Score = 28.9 bits (63), Expect = 9.0
Identities = 22/82 (26%), Positives = 35/82 (42%), Gaps = 8/82 (9%)
Query: 111 LTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMA 170
LT +S + EG CQ +E + PR+ I+ EG+ + C ++
Sbjct: 33107 LTCISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNIN-------EGQNVLFTCE-IS 33158
Query: 171 SKPATTIRWFKGNTELKGKSEV 192
+P+ I WFK N + S V
Sbjct: 33159 GEPSPEIEWFKNNLPISISSNV 33180
>gi|221316762 neurotrimin isoform 4 [Homo sapiens]
Length = 316
Score = 79.0 bits (193), Expect = 8e-15
Identities = 84/318 (26%), Positives = 138/318 (43%), Gaps = 42/318 (13%)
Query: 29 LLLLFSAAALIPTGDGQNLFTK---DVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTI- 84
L LLF +P G F K +VTV +GE AT+ C + D+ V ++ NR TI
Sbjct: 19 LRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTI---DNRVTRVAWLNRSTIL 75
Query: 85 YFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTD-PPQESYTTITVLVP 143
Y + + D R LL+ + ++ + + NV + DEG Y C + TD P+ S + V V
Sbjct: 76 YAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVS 135
Query: 144 PRNLMIDIQKDTAV-EGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVT 202
P+ +++I D ++ EG I + C A +P T+ W + + G +E+ ++ +T
Sbjct: 136 PK--IVEISSDISINEGNNISLTCIA-TGRPEPTVTWRHISPKAVGFVSEDEYLEIQGIT 192
Query: 203 SQLMLKVH---KEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGL-TR 258
+ D PV+ +V+ + V Y P + +G
Sbjct: 193 REQSGDYECSASNDVAAPVVRRVK-------------VTVNYPPYIS-----EAKGTGVP 234
Query: 259 EGDALELTCEAIGKPQPVMVTWVRVDDEMPQH----AVLSGP---NLFINNLNKTDNGTY 311
G L CEA P W + D + + V + P L N+++ D G Y
Sbjct: 235 VGQKGTLQCEASAVPS-AEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNY 293
Query: 312 RCEASNIVGKAHSDYMLY 329
C ASN +G ++ ML+
Sbjct: 294 TCVASNKLGHTNASIMLF 311
>gi|221316757 neurotrimin isoform 3 [Homo sapiens]
Length = 355
Score = 79.0 bits (193), Expect = 8e-15
Identities = 84/318 (26%), Positives = 138/318 (43%), Gaps = 42/318 (13%)
Query: 29 LLLLFSAAALIPTGDGQNLFTK---DVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTI- 84
L LLF +P G F K +VTV +GE AT+ C + D+ V ++ NR TI
Sbjct: 19 LRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTI---DNRVTRVAWLNRSTIL 75
Query: 85 YFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTD-PPQESYTTITVLVP 143
Y + + D R LL+ + ++ + + NV + DEG Y C + TD P+ S + V V
Sbjct: 76 YAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVS 135
Query: 144 PRNLMIDIQKDTAV-EGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVT 202
P+ +++I D ++ EG I + C A +P T+ W + + G +E+ ++ +T
Sbjct: 136 PK--IVEISSDISINEGNNISLTCIA-TGRPEPTVTWRHISPKAVGFVSEDEYLEIQGIT 192
Query: 203 SQLMLKVH---KEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGL-TR 258
+ D PV+ +V+ + V Y P + +G
Sbjct: 193 REQSGDYECSASNDVAAPVVRRVK-------------VTVNYPPYIS-----EAKGTGVP 234
Query: 259 EGDALELTCEAIGKPQPVMVTWVRVDDEMPQH----AVLSGP---NLFINNLNKTDNGTY 311
G L CEA P W + D + + V + P L N+++ D G Y
Sbjct: 235 VGQKGTLQCEASAVPS-AEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNY 293
Query: 312 RCEASNIVGKAHSDYMLY 329
C ASN +G ++ ML+
Sbjct: 294 TCVASNKLGHTNASIMLF 311
>gi|7705413 neurotrimin isoform 1 [Homo sapiens]
Length = 344
Score = 79.0 bits (193), Expect = 8e-15
Identities = 84/318 (26%), Positives = 138/318 (43%), Gaps = 42/318 (13%)
Query: 29 LLLLFSAAALIPTGDGQNLFTK---DVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTI- 84
L LLF +P G F K +VTV +GE AT+ C + D+ V ++ NR TI
Sbjct: 19 LRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTI---DNRVTRVAWLNRSTIL 75
Query: 85 YFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTD-PPQESYTTITVLVP 143
Y + + D R LL+ + ++ + + NV + DEG Y C + TD P+ S + V V
Sbjct: 76 YAGNDKWCLDPRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVS 135
Query: 144 PRNLMIDIQKDTAV-EGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVT 202
P+ +++I D ++ EG I + C A +P T+ W + + G +E+ ++ +T
Sbjct: 136 PK--IVEISSDISINEGNNISLTCIA-TGRPEPTVTWRHISPKAVGFVSEDEYLEIQGIT 192
Query: 203 SQLMLKVH---KEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGL-TR 258
+ D PV+ +V+ + V Y P + +G
Sbjct: 193 REQSGDYECSASNDVAAPVVRRVK-------------VTVNYPPYIS-----EAKGTGVP 234
Query: 259 EGDALELTCEAIGKPQPVMVTWVRVDDEMPQH----AVLSGP---NLFINNLNKTDNGTY 311
G L CEA P W + D + + V + P L N+++ D G Y
Sbjct: 235 VGQKGTLQCEASAVPS-AEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNY 293
Query: 312 RCEASNIVGKAHSDYMLY 329
C ASN +G ++ ML+
Sbjct: 294 TCVASNKLGHTNASIMLF 311
>gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens]
Length = 352
Score = 77.0 bits (188), Expect = 3e-14
Identities = 69/260 (26%), Positives = 117/260 (45%), Gaps = 27/260 (10%)
Query: 74 IQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTDPP-- 131
+ + NP+ +R R + L S ++ + L+ + + DEG Y C+ T P
Sbjct: 78 VAIYNPSMGVSVLAPYR----ERVEFLRPSFTDGTIRLSRLELEDEGVYICEFATFPTGN 133
Query: 132 QESYTTITVLVPPRNLMIDIQKD-TAVEGEEIEV---NCTAMASKPATTIRWFKGNTELK 187
+ES +TV+ P N + Q A +G++ +V CT+ KP + + W T LK
Sbjct: 134 RESQLNLTVMAKPTNWIEGTQAVLRAKKGQDDKVLVATCTSANGKPPSVVSW---ETRLK 190
Query: 188 GKSEVEEW---SDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQ 244
G++E +E + TV S+ L +E + C V + + L VQY+P+
Sbjct: 191 GEAEYQEIRNPNGTVTVISRYRLVPSREAHQQSLACIVNYH--MDRFKESLTLNVQYEPE 248
Query: 245 VHIQ---MTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFIN 301
V I+ + LQ + ++LTC+A P W ++ +P+ LF
Sbjct: 249 VTIEGFDGNWYLQRMD-----VKLTCKADANPPATEYHWTTLNGSLPKGVEAQNRTLFFK 303
Query: 302 N-LNKTDNGTYRCEASNIVG 320
+N + GTY CEA+N +G
Sbjct: 304 GPINYSLAGTYICEATNPIG 323
>gi|7662350 cell recognition molecule Caspr2 precursor [Homo sapiens]
Length = 1331
Score = 76.3 bits (186), Expect = 5e-14
Identities = 38/70 (54%), Positives = 49/70 (70%), Gaps = 2/70 (2%)
Query: 347 AVIGGVVAVVVFAMLCLLIILGRYFARHKGTYFTHEAKGADDAADADTAIINAEGG--QN 404
A+IGGV+AVV+F +LC L+ L RY RHKGTY T+EAKGA+ A AD AI+N + +
Sbjct: 1262 AIIGGVIAVVIFTILCTLVFLIRYMFRHKGTYHTNEAKGAESAESADAAIMNNDPNFTET 1321
Query: 405 NSEEKKEYFI 414
E KKE+ I
Sbjct: 1322 IDESKKEWLI 1331
>gi|115298665 neurotrimin isoform 2 [Homo sapiens]
Length = 344
Score = 75.5 bits (184), Expect = 8e-14
Identities = 80/308 (25%), Positives = 134/308 (43%), Gaps = 42/308 (13%)
Query: 39 IPTGDGQNLFTK---DVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTI-YFRDFRPLKD 94
+P G F K +VTV +GE AT+ C + D+ V ++ NR TI Y + + D
Sbjct: 29 VPVRSGDATFPKAMDNVTVRQGESATLRCTI---DNRVTRVAWLNRSTILYAGNDKWCLD 85
Query: 95 SRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTD-PPQESYTTITVLVPPRNLMIDIQK 153
R LL+ + ++ + + NV + DEG Y C + TD P+ S + V V P+ +++I
Sbjct: 86 PRVVLLSNTQTQYSIEIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVSPK--IVEISS 143
Query: 154 DTAV-EGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVH-- 210
D ++ EG I + C A +P T+ W + + G +E+ ++ +T +
Sbjct: 144 DISINEGNNISLTCIA-TGRPEPTVTWRHISPKAVGFVSEDEYLEIQGITREQSGDYECS 202
Query: 211 -KEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGL-TREGDALELTCE 268
D PV+ +V+ + V Y P + +G G L CE
Sbjct: 203 ASNDVAAPVVRRVK-------------VTVNYPPYIS-----EAKGTGVPVGQKGTLQCE 244
Query: 269 AIGKPQPVMVTWVRVDDEMPQH----AVLSGP---NLFINNLNKTDNGTYRCEASNIVGK 321
A P W + D + + V + P L N+++ D G Y C ASN +G
Sbjct: 245 ASAVPS-AEFQWYKDDKRLIEGKKGVKVENRPFLSKLIFFNVSEHDYGNYTCVASNKLGH 303
Query: 322 AHSDYMLY 329
++ ML+
Sbjct: 304 TNASIMLF 311
>gi|4505505 opioid binding protein/cell adhesion molecule-like
isoform a preproprotein [Homo sapiens]
Length = 345
Score = 74.3 bits (181), Expect = 2e-13
Identities = 85/316 (26%), Positives = 136/316 (43%), Gaps = 37/316 (11%)
Query: 29 LLLLFSAAALIPTGDGQNLFTK---DVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTI- 84
L LLF +P G F K +VTV +GE AT+ C + DD V ++ NR TI
Sbjct: 19 LRLLFLVPTGVPVRSGDATFPKAMDNVTVRQGESATLRCTI---DDRVTRVAWLNRSTIL 75
Query: 85 YFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTD-PPQESYTTITVLVP 143
Y + + D R +L + ++ + + NV + DEG Y C + TD P+ S + V VP
Sbjct: 76 YAGNDKWSIDPRVIILVNTPTQYSIMIQNVDVYDEGPYTCSVQTDNHPKTSRVHLIVQVP 135
Query: 144 PRNLMIDIQKDTAV-EGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVT 202
P+ +++I D V EG + + C A+ +P T+ W + + +G+ V E D Y
Sbjct: 136 PQ--IMNISSDITVNEGSSVTLLCLAI-GRPEPTVTW-RHLSVKEGQGFVSE--DEYLEI 189
Query: 203 SQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDA 262
S + K D C + +++ + + V Y P + + G
Sbjct: 190 SDI-----KRDQSGEYECSALNDVAAPDVRKVK-ITVNYPPYISKAKNTGVS----VGQK 239
Query: 263 LELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSG---------PNLFINNLNKTDNGTYRC 313
L+CEA P M + +E L G L N+++ D G Y C
Sbjct: 240 GILSCEASAVP---MAEFQWFKEETRLATGLDGMRIENKGRMSTLTFFNVSEKDYGNYTC 296
Query: 314 EASNIVGKAHSDYMLY 329
A+N +G ++ LY
Sbjct: 297 VATNKLGNTNASITLY 312
>gi|45594240 limbic system-associated membrane protein [Homo
sapiens]
Length = 338
Score = 74.3 bits (181), Expect = 2e-13
Identities = 90/359 (25%), Positives = 147/359 (40%), Gaps = 51/359 (14%)
Query: 25 RLRLLLLLFSAAALIPTG-----DGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQLLNP 79
R +L L+L L+PTG N T ++TV +G+ A + C V + V L
Sbjct: 9 RKQLPLVLLRLLCLLPTGLPVRSVDFNRGTDNITVRQGDTAILRCVVEDKNSKVAWL--- 65
Query: 80 NRQTIYFRDFRPLK-DSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYTD-PPQESYTT 137
NR I F D R +L S E + + V + DEG Y C + T P+ S
Sbjct: 66 NRSGIIFAGHDKWSLDPRVELEKRHSLEYSLRIQKVDVYDEGSYTCSVQTQHEPKTSQVY 125
Query: 138 ITVLVPPR--NLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRW---FKGNTELKGKSEV 192
+ V VPP+ N+ D+ T EG + + C A +P I W E +G+ E
Sbjct: 126 LIVQVPPKISNISSDV---TVNEGSNVTLVCMA-NGRPEPVITWRHLTPTGREFEGEEEY 181
Query: 193 EEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYP 252
E +L + +E G C+ + + +++ Q + V Y P + T
Sbjct: 182 LE-----------ILGITREQSG-KYECKAANEVSSADVK-QVKVTVNYPPTI----TES 224
Query: 253 LQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQ------HAVLSGPNLFINNLNKT 306
G L CEA P P W R D + + +L + N+ +
Sbjct: 225 KSNEATTGRQASLKCEASAVPAPDF-EWYRDDTRINSANGLEIKSTEGQSSLTVTNVTEE 283
Query: 307 DNGTYRCEASNIVGKAHSDYMLYVYDSRAGEEGSIRAVDHAVIGGV-VAVVVFAMLCLL 364
G Y C A+N +G ++ +L+ GS+R ++ ++ V + ++ ++LCLL
Sbjct: 284 HYGNYTCVAANKLGVTNASLVLF-------RPGSVRGINGSISLAVPLWLLAASLLCLL 335
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 73.6 bits (179), Expect = 3e-13
Identities = 65/229 (28%), Positives = 97/229 (42%), Gaps = 31/229 (13%)
Query: 118 DEGRYFCQLYTDPPQ-ESYTTITVLVPPRNL-------------MIDIQKDTAVEGEEIE 163
D GRY C++ E++ + V PP +L + Q +T G +E
Sbjct: 3359 DSGRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVE 3418
Query: 164 VNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVP--VICQ 221
+C A+ S T +RWFK +L V++ +L++ D ICQ
Sbjct: 3419 FHC-AVPSDRGTQLRWFKEGGQLPPGHSVQDG----------VLRIQNLDQSCQGTYICQ 3467
Query: 222 VEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWV 281
P G Q L +Q P V I + +Q + G A+E C A+G P+P VTW
Sbjct: 3468 AHGP--WGKAQASAQLVIQALPSVLINIRTSVQTVV-VGHAVEFECLALGDPKP-QVTWS 3523
Query: 282 RVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYV 330
+V + V SG + I ++ D G YRC A+N G S +L V
Sbjct: 3524 KVGGHLRPGIVQSGGVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLV 3572
Score = 65.1 bits (157), Expect = 1e-10
Identities = 65/245 (26%), Positives = 95/245 (38%), Gaps = 25/245 (10%)
Query: 105 SELKVSLTNVSISDEGRYFC----QLYTDPPQESYTTITVLVPPRNLMIDIQKD--TAVE 158
S + +++ SD G Y C L T Q T + P + ++ T
Sbjct: 3166 SHAVLQISSAKPSDAGTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEA 3225
Query: 159 GEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPV 218
G + C+A S PA TI W K + L W + ++ +V ++D G
Sbjct: 3226 GHTATLRCSATGS-PAPTIHWSKLRSPLP-------WQHRLEGDTLIIPRVAQQDSG-QY 3276
Query: 219 ICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMV 278
IC PA G+ + L V+ P T P + G+ ++L C A G P P+
Sbjct: 3277 ICNATSPA--GHAEATIILHVESPPYA---TTVPEHASVQAGETVQLQCLAHGTP-PLTF 3330
Query: 279 TWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDSRAGEE 338
W RV +P A L D+G YRC +N VG A + L V G
Sbjct: 3331 QWSRVGSSLPGRATARNELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLV----QGPP 3386
Query: 339 GSIRA 343
GS+ A
Sbjct: 3387 GSLPA 3391
Score = 56.6 bits (135), Expect = 4e-08
Identities = 55/232 (23%), Positives = 93/232 (40%), Gaps = 39/232 (16%)
Query: 108 KVSLTNVSISDEGRYFCQLYTDP-PQESYTTITVL-----------VP--PRNLMIDIQK 153
++ L VS +D G Y C++ P+E+ T++VL VP R + I+
Sbjct: 2101 RLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSS 2160
Query: 154 DTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKED 213
EG+ +++NC A + W K L + + T +L++H+
Sbjct: 2161 SHVAEGQTLDLNCVVPGQAHAQ-VTWHKRGGSLPARHQ----------THGSLLRLHQVT 2209
Query: 214 --DGVPVICQVEHPAVTGNLQTQRYLEVQYK------PQVHIQMTYPLQGLTREGDALEL 265
D +C V +G L+ + ++ P V I+ + EG L+L
Sbjct: 2210 PADSGEYVCHVV--GTSGPLEASVLVTIEASVIPGPIPPVRIESS---SSTVAEGQTLDL 2264
Query: 266 TCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASN 317
+C G+ VTW + +P + G L+I + D G Y C ASN
Sbjct: 2265 SCVVAGQAH-AQVTWYKRGGSLPARHQVRGSRLYIFQASPADAGQYVCRASN 2315
Score = 55.8 bits (133), Expect = 7e-08
Identities = 58/247 (23%), Positives = 92/247 (37%), Gaps = 39/247 (15%)
Query: 105 SELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRN----------LMIDIQKD 154
S+L++ L VS +D G Y C+ + P E + TV VPP + ID
Sbjct: 2974 SQLRLHL--VSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSS 3031
Query: 155 TAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDD 214
T +G++ C ++ W N EL+ + + T+ + +
Sbjct: 3032 TVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNVHISPNGSIITIVGT------RPSN 3085
Query: 215 GVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQ 274
C + G Q+ L V P V + P+ + G A+ L C + G+P+
Sbjct: 3086 HGTYRCVASN--AYGVAQSVVNLSVHGPPTVSVLPEGPV--WVKVGKAVTLECVSAGEPR 3141
Query: 275 PVMVTWVRVDDE-----------MPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAH 323
W R+ M HAVL I++ +D GTY C A N +G A
Sbjct: 3142 S-SARWTRISSTPAKLEQRTYGLMDSHAVLQ-----ISSAKPSDAGTYVCLAQNALGTAQ 3195
Query: 324 SDYMLYV 330
+ V
Sbjct: 3196 KQVEVIV 3202
Score = 55.5 bits (132), Expect = 9e-08
Identities = 68/302 (22%), Positives = 114/302 (37%), Gaps = 43/302 (14%)
Query: 53 TVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSLT 112
TV+EG+ ++C V + ++I T Y R SR Q S L+ L
Sbjct: 2640 TVVEGQTLDLNCVVARQPQAII--------TWYKRGGS--LPSRHQT---HGSHLR--LH 2684
Query: 113 NVSISDEGRYFCQLYTD-PPQESYTTITVL-------VPPRNLMIDIQKDTA--VEGEEI 162
+S++D G Y C+ + E+ I+V P ++ I I+ ++ EGE +
Sbjct: 2685 QMSVADSGEYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETL 2744
Query: 163 EVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQV 222
++NC A + W K L + T S+L L D +C+V
Sbjct: 2745 DLNCVVPGQAHAQ-VTWHKRGGSLPSHHQ--------TRGSRLRLHHVSPADSGEYVCRV 2795
Query: 223 EHPAVTGNLQTQRYLEVQYKPQVHIQMT--------YPLQGLTREGDALELTCEAIGKPQ 274
+ +E VH+ P EG L+L C G+
Sbjct: 2796 MGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAH 2855
Query: 275 PVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDSR 334
VTW + +P + GP L +N ++ D+G Y C+ + G + ++ + S
Sbjct: 2856 -AQVTWHKRGGNLPARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTIEPSS 2914
Query: 335 AG 336
G
Sbjct: 2915 PG 2916
Score = 53.5 bits (127), Expect = 3e-07
Identities = 50/213 (23%), Positives = 83/213 (38%), Gaps = 17/213 (7%)
Query: 111 LTNVSISDEGRYFCQLYTDPPQESYTTITVLVP---PRNLMIDIQKDTAVEGEEIEVNCT 167
L V +D+ +Y C+ ++ Q+ + + PR + + ++ G + + C
Sbjct: 1920 LPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPR-VQVSPERTQVHAGRTVRLYCR 1978
Query: 168 AMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAV 227
A A P+ TI W K L ++ E T + L++ D +C PA
Sbjct: 1979 A-AGVPSATITWRKEGGSLPPQARSER-----TDIATLLIPAITTADAGFYLCVATSPAG 2032
Query: 228 TGNLQTQRYL---EVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVD 284
T + Q + P V I+ + P EG L+L C G VTW R
Sbjct: 2033 TAQARIQVVVLSASDASPPPVKIESSSPS---VTEGQTLDLNCVVAGSAH-AQVTWYRRG 2088
Query: 285 DEMPQHAVLSGPNLFINNLNKTDNGTYRCEASN 317
+P H + G L + ++ D+G Y C N
Sbjct: 2089 GSLPPHTQVHGSRLRLPQVSPADSGEYVCRVEN 2121
Score = 53.5 bits (127), Expect = 3e-07
Identities = 56/215 (26%), Positives = 86/215 (40%), Gaps = 22/215 (10%)
Query: 111 LTNVSISDEGRYFCQLYTD--PPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTA 168
+ N+ S +G Y CQ + Q S + +P + I T V G +E C A
Sbjct: 3453 IQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHAVEFECLA 3512
Query: 169 MASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKV-HKE-DDGVPVICQVEHPA 226
+ P + W K L+ V S ++++ H E D C + A
Sbjct: 3513 LGD-PKPQVTWSKVGGHLRPG----------IVQSGGVVRIAHVELADAGQYRCTATNAA 3561
Query: 227 VTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDE 286
G Q+ L VQ PQ+ + P + G A C A G P P ++W ++D
Sbjct: 3562 --GTTQSHVLLLVQALPQISM----PQEVRVPAGSAAVFPCIASGYPTPD-ISWSKLDGS 3614
Query: 287 MPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGK 321
+P + L L + ++ D GTY C A+N GK
Sbjct: 3615 LPPDSRLENNMLMLPSVRPQDAGTYVCTATNRQGK 3649
Score = 52.0 bits (123), Expect = 1e-06
Identities = 50/245 (20%), Positives = 91/245 (37%), Gaps = 24/245 (9%)
Query: 111 LTNVSISDEGRYFCQ-LYTDPPQESYTTITV--------LVPPRNLMIDIQKDTAVEGEE 161
L S +D G Y C+ L + P E+ +T+ L + I+ EG+
Sbjct: 2394 LYQASPADSGEYVCRVLGSSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQT 2453
Query: 162 IEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQ 221
+++NC +A + + W K L + +V S+L L D +C+
Sbjct: 2454 LDLNCL-VAGQAHAQVTWHKRGGSLPARHQVHG--------SRLRLLQVTPADSGEYVCR 2504
Query: 222 VEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQ-----GLTREGDALELTCEAIGKPQPV 276
V + T ++ + + YP++ G L+L C + P
Sbjct: 2505 VVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNC-LVASQAPH 2563
Query: 277 MVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDSRAG 336
+TW + +P + G L I + D+G Y C SN G + ++ + S +
Sbjct: 2564 TITWYKRGGSLPSRHQIVGSRLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSS 2623
Query: 337 EEGSI 341
S+
Sbjct: 2624 HVPSV 2628
Score = 51.2 bits (121), Expect = 2e-06
Identities = 52/236 (22%), Positives = 91/236 (38%), Gaps = 34/236 (14%)
Query: 114 VSISDEGRYFCQLYTDPPQESYTTITVLV------PPRNLMIDIQKDTAVEGEEIEVNCT 167
++ +D G Y C + T P + I V+V P + I+ + EG+ +++NC
Sbjct: 2015 ITTADAGFYLC-VATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTLDLNCV 2073
Query: 168 AMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAV 227
S A + W++ L ++V S+L L D +C+VE+
Sbjct: 2074 VAGSAHAQ-VTWYRRGGSLPPHTQVHG--------SRLRLPQVSPADSGEYVCRVEN--- 2121
Query: 228 TGNLQTQRYLEVQYKPQVHIQMTY-PLQGLTR------------EGDALELTCEAIGKPQ 274
G+ + + V H +Y P+ G TR EG L+L C G+
Sbjct: 2122 -GSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAH 2180
Query: 275 PVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYV 330
VTW + +P G L ++ + D+G Y C G + ++ +
Sbjct: 2181 -AQVTWHKRGGSLPARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVLVTI 2235
Score = 50.1 bits (118), Expect = 4e-06
Identities = 48/239 (20%), Positives = 94/239 (39%), Gaps = 28/239 (11%)
Query: 108 KVSLTNVSISDEGRYFCQLYTDP-PQESYTTITV----------LVPPRNLMIDIQKDTA 156
++ + V+ +D G Y C + +E+ +T+ + PP + I+ T
Sbjct: 2584 RLRIPQVTPADSGEYVCHVSNGAGSRETSLIVTIQGSGSSHVPSVSPP--IRIESSSPTV 2641
Query: 157 VEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGV 216
VEG+ +++NC +A +P I W+K L + + T S L L D
Sbjct: 2642 VEGQTLDLNC-VVARQPQAIITWYKRGGSLPSRHQ--------THGSHLRLHQMSVADSG 2692
Query: 217 PVICQVEH--PAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLT---REGDALELTCEAIG 271
+C+ + A+ ++ M ++ + EG+ L+L C G
Sbjct: 2693 EYVCRANNNIDALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPG 2752
Query: 272 KPQPVMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYV 330
+ VTW + +P H G L +++++ D+G Y C G + ++ +
Sbjct: 2753 QAH-AQVTWHKRGGSLPSHHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLEASVLVTI 2810
Score = 47.0 bits (110), Expect = 3e-05
Identities = 52/242 (21%), Positives = 89/242 (36%), Gaps = 33/242 (13%)
Query: 111 LTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRN------------LMIDIQKDTAVE 158
L VS +D G Y CQ+ T ++ V + P + + I+ E
Sbjct: 2880 LNQVSPADSGEYSCQV-TGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTE 2938
Query: 159 GEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPV 218
G+ +++NC A + W+K L + + T SQL L + D
Sbjct: 2939 GQTLDLNCVVPGQAHAQ-VTWYKRGGSLPARHQ--------THGSQLRLHLVSPADSGEY 2989
Query: 219 ICQVEHPAVTGNLQTQRYLEV-------QYKPQVHIQMTYPLQGLTREGDALELTCEAIG 271
+C+ + G Q + Y+ + + P ++G C
Sbjct: 2990 VCRAA--SGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHD 3047
Query: 272 KPQPVMVTWVRVDDEMPQHAVLS--GPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLY 329
P+ + W + E+ + +S G + I +++GTYRC ASN G A S L
Sbjct: 3048 GAAPISLEWKTRNQELEDNVHISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNLS 3107
Query: 330 VY 331
V+
Sbjct: 3108 VH 3109
Score = 46.2 bits (108), Expect = 5e-05
Identities = 47/218 (21%), Positives = 81/218 (37%), Gaps = 30/218 (13%)
Query: 111 LTNVSISDEGRYFCQLY-TDPPQESYTTITVL-------VPPRNLMIDIQKDTAVEGEEI 162
L V+ +D G Y C + T P E+ +T+ +PP + I+ T EG+ +
Sbjct: 2205 LHQVTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPP--VRIESSSSTVAEGQTL 2262
Query: 163 EVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQV 222
+++C +A + + W+K L + +V S+L + D +C+
Sbjct: 2263 DLSCV-VAGQAHAQVTWYKRGGSLPARHQVRG--------SRLYIFQASPADAGQYVCRA 2313
Query: 223 EHP-------AVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQP 275
+ VTG + I+ P EG L+L C G+
Sbjct: 2314 SNGMEASITVTVTGTQGANLAYPAGSTQPIRIE---PSSSQVAEGQTLDLNCVVPGQSH- 2369
Query: 276 VMVTWVRVDDEMPQHAVLSGPNLFINNLNKTDNGTYRC 313
VTW + +P G L + + D+G Y C
Sbjct: 2370 AQVTWHKRGGSLPVRHQTHGSLLRLYQASPADSGEYVC 2407
Score = 45.4 bits (106), Expect = 9e-05
Identities = 47/225 (20%), Positives = 90/225 (40%), Gaps = 14/225 (6%)
Query: 113 NVSISDEGRYFCQLYTDPPQESYTTITVLVP-----PRNLMIDIQKDTAVE-GEEIEVNC 166
+V SD G Y C + Q + + +LV P + ++ Q+ +V G ++ C
Sbjct: 1735 SVQPSDAGVYICTC-RNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFIC 1793
Query: 167 TAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPA 226
TA + PA T+ W + + K + +++ + T+ + V D G +C +
Sbjct: 1794 TAKSKSPAYTLVWTRLHNG-KLPTRAMDFNGILTIRN-----VQLSDAGT-YVCTGSNMF 1846
Query: 227 VTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDE 286
+++ + +P Q + G E C A G P P + +
Sbjct: 1847 AMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEWTGGPGGQ 1906
Query: 287 MPQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVY 331
+P A + G L + + TD Y C A + G+ + +L+V+
Sbjct: 1907 LPAKAQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVH 1951
Score = 38.9 bits (89), Expect = 0.009
Identities = 52/239 (21%), Positives = 85/239 (35%), Gaps = 38/239 (15%)
Query: 109 VSLTNVSISDEGRYFC-------------QLYTDPPQESYTTITVLVPPRNLMIDIQKDT 155
+++ NV +SD G Y C L+ + + PP+ T
Sbjct: 1825 LTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGTLSAPVVSIHPPQL--------T 1876
Query: 156 AVEGEEIEVNCTAMASKPATTIRWFKG-NTELKGKSEVEEWSDMYTVTSQLMLKVHKEDD 214
G+ E C+A S P T+ W G +L K+++ L L + D
Sbjct: 1877 VQPGQLAEFRCSATGS-PTPTLEWTGGPGGQLPAKAQIH--------GGILRLPAVEPTD 1927
Query: 215 GVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQ 274
+C+ A G + L V +Q++ P + G + L C A G P
Sbjct: 1928 QAQYLCRAHSSA--GQQVARAVLHVHGGGGPRVQVS-PERTQVHAGRTVRLYCRAAGVPS 1984
Query: 275 PVMVTWVRVDDEMPQHAVLSGPN---LFINNLNKTDNGTYRCEASNIVGKAHSDYMLYV 330
+TW + +P A + L I + D G Y C A++ G A + + V
Sbjct: 1985 -ATITWRKEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVATSPAGTAQARIQVVV 2042
Score = 37.4 bits (85), Expect = 0.025
Identities = 26/85 (30%), Positives = 40/85 (47%), Gaps = 11/85 (12%)
Query: 243 PQVHIQMTYPLQGL-TREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPN---- 297
PQV +T P + + G + TC AIG P P+ + W +P H ++ +
Sbjct: 406 PQV---VTPPRESIQASRGQTVTFTCVAIGVPTPI-INWRLNWGHIPSHPRVTVTSEGGR 461
Query: 298 --LFINNLNKTDNGTYRCEASNIVG 320
L I ++ ++D G Y CEA N G
Sbjct: 462 GTLIIRDVKESDQGAYTCEAMNARG 486
Score = 33.9 bits (76), Expect = 0.28
Identities = 22/77 (28%), Positives = 33/77 (42%), Gaps = 1/77 (1%)
Query: 258 REGDALELTCEAIGKPQPVMVTWVRVDD-EMPQHAVLSGPNLFINNLNKTDNGTYRCEAS 316
R G + C A K + W R+ + ++P A+ L I N+ +D GTY C S
Sbjct: 1784 RPGADVTFICTAKSKSPAYTLVWTRLHNGKLPTRAMDFNGILTIRNVQLSDAGTYVCTGS 1843
Query: 317 NIVGKAHSDYMLYVYDS 333
N+ L+V S
Sbjct: 1844 NMFAMDQGTATLHVQAS 1860
>gi|239755187 PREDICTED: similar to hemicentin 2 [Homo sapiens]
Length = 1215
Score = 73.2 bits (178), Expect = 4e-13
Identities = 76/306 (24%), Positives = 119/306 (38%), Gaps = 33/306 (10%)
Query: 52 VTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVSL 111
V V+EG+ ++ C ++ P + + +D RPL + S + L
Sbjct: 777 VRVLEGQPVSLPC--------IVLAGRPLPERHWLKDGRPLPPGSRHSIRADGS---LHL 825
Query: 112 TNVSISDEGRYFC-QLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMA 170
GRY C T Q + V VPPR + EG + C A +
Sbjct: 826 DRALQEHAGRYSCVATNTAGSQHRDVELVVQVPPR-IHPTATHHITNEGVPASLPCVA-S 883
Query: 171 SKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQ--LMLKVHKEDDGVPVICQVEHPAVT 228
PA TI W K L + Y V+ + L++ D +C +
Sbjct: 884 GVPAPTITWTKETNALTSRGP------HYNVSKEGTLLIAQPSAQDAGAYVCTATN--TV 935
Query: 229 GNLQTQRYLEVQYKPQVHIQ----MTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVD 284
G + L V KP++H+ PLQ + G+ + L CEA G P P +VTW +
Sbjct: 936 GFSSQEMRLSVNTKPRIHMNGSRNANVPLQVTAKAGEEVTLDCEAKGSPPP-LVTWTKDS 994
Query: 285 DEMP----QHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDSRAGEEGS 340
+P ++ +L +L + + D+G Y C ASN G A Y+L V + + S
Sbjct: 995 RPVPPITNRYGLLPSGSLRLAQVQVGDSGHYECTASNPAGSASHRYVLGVQGRTSWQPQS 1054
Query: 341 IRAVDH 346
+ H
Sbjct: 1055 LPVPHH 1060
Score = 55.5 bits (132), Expect = 9e-08
Identities = 70/284 (24%), Positives = 118/284 (41%), Gaps = 30/284 (10%)
Query: 51 DVTVIEGEVATISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKVS 110
+VTV GE A +SC+V L + RD+R L S ++ ++L +
Sbjct: 408 NVTVSPGETAVLSCRV---------LGEAPYNLTWVRDWRVLPASTGRVAQL--ADLSLE 456
Query: 111 LTNVSISDEGRYFCQLYTDPPQESYTTITVLV-PPRNLMIDIQKDTAVEGEEIEVNCTAM 169
++ + +D GRY C + ++ + ++ +LV + I +G E++V+C+A
Sbjct: 457 ISGIIPTDGGRYQC-VASNANGVTRASVWLLVREAPQVSIHTSSQHFSQGVEVKVSCSA- 514
Query: 170 ASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTG 229
+ P I W + + L+ S + L+++ +D CQ + T
Sbjct: 515 SGYPTPHISWSRESQALQEDSRIH-----VDAQGTLIIQGVAPEDAGNYSCQATNEVGT- 568
Query: 230 NLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEM-- 287
Q + + Y + + L G+ L CEA G P P V W R EM
Sbjct: 569 ---DQETVTLYYTDPPSVSAVNAVV-LVAVGEEAVLVCEASGVPPP-RVIWYRGGLEMIL 623
Query: 288 -PQHAVLSGPNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYV 330
P+ + S L I + D GTY C A N +G A ++ L V
Sbjct: 624 APEGS--SSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 665
Score = 54.7 bits (130), Expect = 2e-07
Identities = 61/244 (25%), Positives = 87/244 (35%), Gaps = 52/244 (21%)
Query: 111 LTNVSISDEGRYFCQL--------------YTDPPQESYTTITVLVPPRNLMIDIQKDTA 156
+ V+ D G Y CQ YTDPP S VLV
Sbjct: 547 IQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLV-------------- 592
Query: 157 VEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEVEEWSDMYTVTSQLMLKVHKEDDGV 216
GEE + C A P I W++G E+ E + +L + +E D
Sbjct: 593 AVGEEAVLVCEASGVPPPRVI-WYRGGLEMILAPEGSS-------SGKLRIPAAQERDAG 644
Query: 217 PVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPV 276
C+ + G+ + L V + PQ+ P G + L C A G+P P
Sbjct: 645 TYTCRAVNEL--GDASAEIQLAVGHAPQL---TELPRDVTVELGRSALLACRATGRPPPT 699
Query: 277 MVTWVRVDDEMPQHAVLSGPN----------LFINNLNKTDNGTYRCEASNIVGKAHSDY 326
VTW R D + + +G LF ++ D Y CEA N+ GK ++
Sbjct: 700 -VTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEA 758
Query: 327 MLYV 330
L V
Sbjct: 759 RLIV 762
Score = 50.4 bits (119), Expect = 3e-06
Identities = 72/297 (24%), Positives = 120/297 (40%), Gaps = 37/297 (12%)
Query: 62 ISCQVNKSDDSVIQLLNPNRQTIYFRDFRPLKDSRFQLLNFSSSELKV-SLTNVSISDEG 120
+SC V+ + +QL + R F+ +S +++L S +E T VS + G
Sbjct: 329 VSCSVHSALPFRLQLRRGEARLGEERHFQESGNSSWEILRASKAEEGTYECTAVSRAGTG 388
Query: 121 RYFCQLY-TDPPQESYTTITVLVPPRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRW 179
R Q+ TDPP + LVP N+ T GE ++C + P + W
Sbjct: 389 RAKAQIVVTDPPPQ-------LVPAPNV-------TVSPGETAVLSCRVLGEAPYN-LTW 433
Query: 180 FKGNTELKGKS-EVEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLE 238
+ L + V + +D+ S ++ DG C + G + +L
Sbjct: 434 VRDWRVLPASTGRVAQLADLSLEISGII-----PTDGGRYQCVASN--ANGVTRASVWLL 486
Query: 239 VQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHA---VLSG 295
V+ PQV I + +G ++++C A G P P ++W R + + + V +
Sbjct: 487 VREAPQVSIHTS---SQHFSQGVEVKVSCSASGYPTP-HISWSRESQALQEDSRIHVDAQ 542
Query: 296 PNLFINNLNKTDNGTYRCEASNIVGKAHSDYMLYVYDSRAGEEGSIRAVDHAVIGGV 352
L I + D G Y C+A+N VG LY D S+ AV+ V+ V
Sbjct: 543 GTLIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTD-----PPSVSAVNAVVLVAV 594
>gi|157819143 IgLON family member 5 [Homo sapiens]
Length = 336
Score = 72.8 bits (177), Expect = 5e-13
Identities = 88/326 (26%), Positives = 130/326 (39%), Gaps = 44/326 (13%)
Query: 22 PGLRLRLLL------LLFSAAALIPTGDGQNLFTKDVTVIEGEVATISCQVNKSDDSVIQ 75
PG RLRLL L + L+ N + TV EG+ AT+SC + D+ V +
Sbjct: 6 PGARLRLLAAAALAGLAVISRGLLSQSLEFNSPADNYTVCEGDNATLSCFI---DEHVTR 62
Query: 76 LLNPNRQTI-YFRDFRPLKDSRFQLLNFSSSELKVSLTNVSISDEGRYFCQLYT-DPPQE 133
+ NR I Y + R D R +LL + E + +T V + DEG Y C T P
Sbjct: 63 VAWLNRSNILYAGNDRWTSDPRVRLLINTPEEFSILITEVGLGDEGLYTCSFQTRHQPYT 122
Query: 134 SYTTITVLVPPRNLMIDIQKDTAV-EGEEIEVNCTAMASKPATTIRWFKGNTELKGKSEV 192
+ + V VP R +++I V EG + + C A+ +P T+ W + + E+
Sbjct: 123 TQVYLIVHVPAR--IVNISSPVTVNEGGNVNLLCLAV-GRPEPTVTWRQLRDGFTSEGEI 179
Query: 193 EEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYL-EVQYKPQVHIQMTY 251
E SD+ + C V H V ++R L V Y P + T
Sbjct: 180 LEISDI------------QRGQAGEYEC-VTHNGVNSAPDSRRVLVTVNYPPTI----TD 222
Query: 252 PLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSG---------PNLFINN 302
T G A L CEA+ P P W + DD + G L N
Sbjct: 223 VTSARTALGRAALLRCEAMAVP-PADFQWYK-DDRLLSSGTAEGLKVQTERTRSMLLFAN 280
Query: 303 LNKTDNGTYRCEASNIVGKAHSDYML 328
++ G Y C A+N +G + + L
Sbjct: 281 VSARHYGNYTCRAANRLGASSASMRL 306
>gi|166295173 kin of IRRE like [Homo sapiens]
Length = 757
Score = 71.6 bits (174), Expect = 1e-12
Identities = 46/183 (25%), Positives = 84/183 (45%), Gaps = 7/183 (3%)
Query: 104 SSELKVSLTNVSISDEGRYFCQLYTDPPQESYTTITVLVPPRNLMIDIQKDTAVE-GEEI 162
+ + + +T+ +SD+ Y CQ + +TVL+PP + ID ++ G
Sbjct: 80 AGQYNLEITDAELSDDASYECQATEAALRSRRAKLTVLIPPEDTRIDGGPVILLQAGTPH 139
Query: 163 EVNCTAMASKPATTIRWFKGNTELKG---KSEVEEWSDMYTVTSQLMLKVHKEDDGVPVI 219
+ C A +KPA TI WF+ T+ +G +E+ + T SQL++ D G
Sbjct: 140 NLTCRAFNAKPAATIIWFRDGTQQEGAVASTELLKDGKRETTVSQLLINPTDLDIGRVFT 199
Query: 220 CQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTYPLQGLTREGDALELTCEAIGKPQPVMVT 279
C+ + A+ +T L+V + P V + + +EG+ + TC+A P+ +
Sbjct: 200 CRSMNEAIPSGKETSIELDVHHPPTVTLSIE---PQTVQEGERVVFTCQATANPEILGYR 256
Query: 280 WVR 282
W +
Sbjct: 257 WAK 259
Score = 67.8 bits (164), Expect = 2e-11
Identities = 74/261 (28%), Positives = 111/261 (42%), Gaps = 30/261 (11%)
Query: 79 PNRQTIYFRDFRPLKDS--RFQLLNFSSSELKVS--LTNVSISDEGRYF-CQLYTDP-PQ 132
P I+FRD + + +LL E VS L N + D GR F C+ + P
Sbjct: 150 PAATIIWFRDGTQQEGAVASTELLKDGKRETTVSQLLINPTDLDIGRVFTCRSMNEAIPS 209
Query: 133 ESYTTITVLVP-PRNLMIDIQKDTAVEGEEIEVNCTAMASKPATTIRWFKGNTELKGKSE 191
T+I + V P + + I+ T EGE + C A A+ RW KG ++ E
Sbjct: 210 GKETSIELDVHHPPTVTLSIEPQTVQEGERVVFTCQATANPEILGYRWAKGGFLIEDAHE 269
Query: 192 VEEWSDMYTVTSQLMLKVHKEDDGVPVICQVEHPAVTGNLQTQRYLEVQYKPQVHIQMTY 251
S+ V PV C+V + + N+ T + V + P++ +
Sbjct: 270 -----------SRYETNVDYSFFTEPVSCEVHNKVGSTNVST--LVNVHFAPRIVVD--- 313
Query: 252 PLQGLTREGDALELTCEAIGKPQPVMVTWVRVDDEMPQHAVLSGPN-LFINNLNKTDNGT 310
P T G + LTC +G P P+ +TW + D M VLS N L + ++ + D GT
Sbjct: 314 PKPTTTDIGSDVTLTCVWVGNP-PLTLTWTKKDSNM----VLSNSNQLLLKSVTQADAGT 368
Query: 311 YRCEA-SNIVGKAHSDYMLYV 330
Y C A +G A + LYV
Sbjct: 369 YTCRAIVPRIGVAEREVPLYV 389
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.387
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,052,324
Number of Sequences: 37866
Number of extensions: 712808
Number of successful extensions: 4600
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 155
Number of HSP's successfully gapped in prelim test: 282
Number of HSP's that attempted gapping in prelim test: 2511
Number of HSP's gapped (non-prelim): 1651
length of query: 414
length of database: 18,247,518
effective HSP length: 105
effective length of query: 309
effective length of database: 14,271,588
effective search space: 4409920692
effective search space used: 4409920692
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.