Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 109452587
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|109452587 family with sequence similarity 98, member B
isoform 1 [Homo sapiens]
(433 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|109452587 family with sequence similarity 98, member B isofor... 902 0.0
gi|109452589 family with sequence similarity 98, member B isofor... 591 e-169
gi|56699482 hypothetical protein LOC25940 [Homo sapiens] 447 e-125
gi|116812620 hypothetical protein LOC147965 [Homo sapiens] 191 1e-48
gi|55956899 keratin 9 [Homo sapiens] 118 9e-27
gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo sap... 117 2e-26
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] 116 5e-26
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] 116 5e-26
gi|195972866 keratin 10 [Homo sapiens] 109 4e-24
gi|109255251 loricrin [Homo sapiens] 107 2e-23
gi|109148552 keratin 3 [Homo sapiens] 107 2e-23
gi|119395750 keratin 1 [Homo sapiens] 107 3e-23
gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b... 105 1e-22
gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isofor... 100 3e-21
gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform... 100 3e-21
gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo sapi... 99 7e-21
gi|12056465 fibrillarin [Homo sapiens] 94 2e-19
gi|47132620 keratin 2 [Homo sapiens] 94 3e-19
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 92 9e-19
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s... 86 7e-17
gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapi... 86 9e-17
gi|153791670 keratin 76 [Homo sapiens] 85 1e-16
gi|4504445 heterogeneous nuclear ribonucleoprotein A1 isoform a ... 82 9e-16
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 82 1e-15
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 82 1e-15
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 82 1e-15
gi|4504733 insulin receptor substrate 4 [Homo sapiens] 81 2e-15
gi|15011916 nucleolar protein family A, member 1 [Homo sapiens] 81 2e-15
gi|9506713 nucleolar protein family A, member 1 [Homo sapiens] 81 2e-15
gi|7710145 methyl-CpG binding domain protein 2 testis-specific i... 75 9e-14
>gi|109452587 family with sequence similarity 98, member B isoform 1
[Homo sapiens]
Length = 433
Score = 902 bits (2332), Expect = 0.0
Identities = 433/433 (100%), Positives = 433/433 (100%)
Query: 1 MRGPEPGPQPTMEGDVLDTLEALGYKGPLLEEQALTKAAEGGLSSPEFSELCIWLGSQIK 60
MRGPEPGPQPTMEGDVLDTLEALGYKGPLLEEQALTKAAEGGLSSPEFSELCIWLGSQIK
Sbjct: 1 MRGPEPGPQPTMEGDVLDTLEALGYKGPLLEEQALTKAAEGGLSSPEFSELCIWLGSQIK 60
Query: 61 SLCNLEESITSAGRDDLESFQLEISGFLKEMACPYSVLISGDIKDRLKKKEDCLKLLLFL 120
SLCNLEESITSAGRDDLESFQLEISGFLKEMACPYSVLISGDIKDRLKKKEDCLKLLLFL
Sbjct: 61 SLCNLEESITSAGRDDLESFQLEISGFLKEMACPYSVLISGDIKDRLKKKEDCLKLLLFL 120
Query: 121 STELQASQILQNKKHKNSQLDKNSEVYQEVQAMFDTLGIPKSTTSDIPHMLNQVESKVKD 180
STELQASQILQNKKHKNSQLDKNSEVYQEVQAMFDTLGIPKSTTSDIPHMLNQVESKVKD
Sbjct: 121 STELQASQILQNKKHKNSQLDKNSEVYQEVQAMFDTLGIPKSTTSDIPHMLNQVESKVKD 180
Query: 181 ILSKVQKNHVGKPLLKMDLNSEQAEQLERINDALSCEYECRRRMLMKRLDVTVQSFGWSD 240
ILSKVQKNHVGKPLLKMDLNSEQAEQLERINDALSCEYECRRRMLMKRLDVTVQSFGWSD
Sbjct: 181 ILSKVQKNHVGKPLLKMDLNSEQAEQLERINDALSCEYECRRRMLMKRLDVTVQSFGWSD 240
Query: 241 RAKVKTDDIARIYQPKRYALSPKTTITMAHLLAAREDLSKIIRTSSGTSREKTACAINKV 300
RAKVKTDDIARIYQPKRYALSPKTTITMAHLLAAREDLSKIIRTSSGTSREKTACAINKV
Sbjct: 241 RAKVKTDDIARIYQPKRYALSPKTTITMAHLLAAREDLSKIIRTSSGTSREKTACAINKV 300
Query: 301 LMGRVPDRGGRPNEIEPPPPEMPPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWG 360
LMGRVPDRGGRPNEIEPPPPEMPPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWG
Sbjct: 301 LMGRVPDRGGRPNEIEPPPPEMPPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWG 360
Query: 361 GGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGG 420
GGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGG
Sbjct: 361 GGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGG 420
Query: 421 GGGGGGGGGYRRY 433
GGGGGGGGGYRRY
Sbjct: 421 GGGGGGGGGYRRY 433
>gi|109452589 family with sequence similarity 98, member B isoform 2
[Homo sapiens]
Length = 330
Score = 591 bits (1523), Expect = e-169
Identities = 300/300 (100%), Positives = 300/300 (100%)
Query: 1 MRGPEPGPQPTMEGDVLDTLEALGYKGPLLEEQALTKAAEGGLSSPEFSELCIWLGSQIK 60
MRGPEPGPQPTMEGDVLDTLEALGYKGPLLEEQALTKAAEGGLSSPEFSELCIWLGSQIK
Sbjct: 1 MRGPEPGPQPTMEGDVLDTLEALGYKGPLLEEQALTKAAEGGLSSPEFSELCIWLGSQIK 60
Query: 61 SLCNLEESITSAGRDDLESFQLEISGFLKEMACPYSVLISGDIKDRLKKKEDCLKLLLFL 120
SLCNLEESITSAGRDDLESFQLEISGFLKEMACPYSVLISGDIKDRLKKKEDCLKLLLFL
Sbjct: 61 SLCNLEESITSAGRDDLESFQLEISGFLKEMACPYSVLISGDIKDRLKKKEDCLKLLLFL 120
Query: 121 STELQASQILQNKKHKNSQLDKNSEVYQEVQAMFDTLGIPKSTTSDIPHMLNQVESKVKD 180
STELQASQILQNKKHKNSQLDKNSEVYQEVQAMFDTLGIPKSTTSDIPHMLNQVESKVKD
Sbjct: 121 STELQASQILQNKKHKNSQLDKNSEVYQEVQAMFDTLGIPKSTTSDIPHMLNQVESKVKD 180
Query: 181 ILSKVQKNHVGKPLLKMDLNSEQAEQLERINDALSCEYECRRRMLMKRLDVTVQSFGWSD 240
ILSKVQKNHVGKPLLKMDLNSEQAEQLERINDALSCEYECRRRMLMKRLDVTVQSFGWSD
Sbjct: 181 ILSKVQKNHVGKPLLKMDLNSEQAEQLERINDALSCEYECRRRMLMKRLDVTVQSFGWSD 240
Query: 241 RAKVKTDDIARIYQPKRYALSPKTTITMAHLLAAREDLSKIIRTSSGTSREKTACAINKV 300
RAKVKTDDIARIYQPKRYALSPKTTITMAHLLAAREDLSKIIRTSSGTSREKTACAINKV
Sbjct: 241 RAKVKTDDIARIYQPKRYALSPKTTITMAHLLAAREDLSKIIRTSSGTSREKTACAINKV 300
>gi|56699482 hypothetical protein LOC25940 [Homo sapiens]
Length = 518
Score = 447 bits (1149), Expect = e-125
Identities = 247/464 (53%), Positives = 308/464 (66%), Gaps = 46/464 (9%)
Query: 12 MEGDVLDTLEALGYKGPLLEEQALTKAAEGGLSSPEFSELCIWLGSQIKSLCNLEESITS 71
ME D+L++LE LGYKGPLLE+ AL++A G SSPEF++LC WL S+++ LC LEE++ +
Sbjct: 6 METDILESLEDLGYKGPLLEDGALSQAVSAGASSPEFTKLCAWLVSELRVLCKLEENVQA 65
Query: 72 AGR-DDLESFQLEISGFLKEMACPYSVLISGDIKDRLKKKEDCLKLLLFLSTELQASQIL 130
+ E FQLE+SG L EM CPY L SGD+ RL +++CL LL +L +EL+A+++L
Sbjct: 66 TNSPSEAEEFQLEVSGLLGEMNCPYLSLTSGDVTKRLLIQKNCLLLLTYLISELEAARML 125
Query: 131 -QNKKHKNSQLDKNSEVYQEVQAMFDTLGIPKSTTS-DIPHMLNQVESKVKDILSKVQKN 188
N K +Q SEV+QE++ + LG+ K + + + +E K+K+ L+KV N
Sbjct: 126 CVNAPPKKAQEGGGSEVFQELKGICIALGMSKPPANITMFQFFSGIEKKLKETLAKVPPN 185
Query: 189 HVGKPLLKMDLNSEQAEQLERINDALSCEYECRRRMLMKRLDVTVQSFGWSDRAKVKTDD 248
HVGKPLLK + E++E IN A++ EYE RR++L+KRLDVTVQSFGWSDRAK +T+
Sbjct: 186 HVGKPLLKKPMGPAHWEKIEAINQAIANEYEVRRKLLIKRLDVTVQSFGWSDRAKSQTEK 245
Query: 249 IARIYQPKRYALSPKTTITMAHLLAAREDLSKIIRTSSGTSREKTACAINKVLMGRVPDR 308
+A++YQPKR LSPKTTI++AHLLAAR+DLSKI+RTSSG+ REKTACAINKVLMGRVPDR
Sbjct: 246 LAKVYQPKRSVLSPKTTISVAHLLAARQDLSKILRTSSGSIREKTACAINKVLMGRVPDR 305
Query: 309 GGRPNEIEPPPPEMPPWQKRQEG----GGGRGGWGGG------GGGGGRGGGGGGGGRGG 358
GGRPNEIEPPPPEMPPWQKRQ+G GGRGG GG GG GG GGG GGRGG
Sbjct: 306 GGRPNEIEPPPPEMPPWQKRQDGPQQQTGGRGGGRGGYEHSSYGGRGGHEQGGGRGGRGG 365
Query: 359 WGGGGGGWGGGGGGGGGWGGGGGGGRG----------GFQGRGDYGGR-------GGYGG 401
+ GG G G G GGW GG GG G GFQ G +GG GGYGG
Sbjct: 366 YDHGGRGGGRGNKHQGGWTDGGSGGGGGYQDGGYRDSGFQPGGYHGGHSSGGYQGGGYGG 425
Query: 402 --------RGGYGGRGY--------GDPYGGGGGGGGGGGGGGG 429
GY G GY G +G GGG GG GG GG
Sbjct: 426 FQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGG 469
Score = 54.3 bits (129), Expect = 2e-07
Identities = 39/106 (36%), Positives = 45/106 (42%), Gaps = 22/106 (20%)
Query: 331 GGGGRGGWGGGGGGG--------GRGGGGGG-------------GGRGGWGGGGGGWGGG 369
GG GG+ GGG GG G G GGG G RGG GG GG GG
Sbjct: 411 GGHSSGGYQGGGYGGFQTSSSYTGSGYQGGGYQQDNRYQDGGHHGDRGGGRGGRGGRGGR 470
Query: 370 GGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGG-RGGYGGRGYGDPY 414
GG G GG GG G + G + +GG + + G G G Y
Sbjct: 471 GGRAGQGGGWGGRGSQNYHQGGQFEQHFQHGGYQYNHSGFGQGRHY 516
Score = 52.8 bits (125), Expect = 6e-07
Identities = 26/50 (52%), Positives = 28/50 (56%)
Query: 329 QEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGG 378
Q+ + G G GGGRGG GG GGRGG G GGGWGG G GG
Sbjct: 443 QQDNRYQDGGHHGDRGGGRGGRGGRGGRGGRAGQGGGWGGRGSQNYHQGG 492
>gi|116812620 hypothetical protein LOC147965 [Homo sapiens]
Length = 349
Score = 191 bits (485), Expect = 1e-48
Identities = 121/342 (35%), Positives = 189/342 (55%), Gaps = 31/342 (9%)
Query: 16 VLDTLEALGYKGPLLEEQALTKAAEGGLSSPEFSELCIWLGSQIKSLCNLEESITSAGRD 75
V L ALGY G + AA G S P+F LC+ L +++ +L LE+ AG +
Sbjct: 14 VAQDLLALGYGG-------VPGAASRGASCPDFRGLCVRLAAELATLGALEQQ-REAGAE 65
Query: 76 DL---------ESFQLEISGFLKEMACPYSVLISGDIKDRLKKKEDCLKLLLFLSTELQA 126
L E F ++ L+E+ CP L GD L++ L+LL FL +ELQA
Sbjct: 66 VLSAGDGPGAEEDFLRQLGSLLRELHCPDRALCGGDGAAALREPGAGLRLLRFLCSELQA 125
Query: 127 SQIL--------QNKKHKNSQLDKNSEVYQEVQAMFDTLGIPKSTT-SDIPHMLNQVESK 177
+++L + + + + + QE+ LG+P+ + +L ++ +K
Sbjct: 126 TRLLCLRSLLDPSPRPPLGEGVVEGAGMVQELDLTLQALGLPRPAPGTPASQLLQELHAK 185
Query: 178 VKDILSKVQKNHVGKPLLKMDLNSEQAEQLERINDALSCEYECRRRMLMKRLDVTVQSFG 237
+ ++ + + +PLL L++ + E LE ++ +L +Y CRR +L+KRLD+T +F
Sbjct: 186 ISELQPSLPPGSL-QPLLSCSLDAPRWEALESLSQSLRDQYRCRRCLLLKRLDLTTSAFH 244
Query: 238 WSDRAKVKTDDIARIYQPKRYALSPKTTITMAHLLAAREDLSKIIRTSSGTSREKTACAI 297
WSDRA+ + + + + P R L+P++ I++AH+LAAR DLS ++ +S R T CAI
Sbjct: 245 WSDRAEAQGEAMRAVLIPIREVLTPESDISIAHVLAARADLSCLVPATSVAVRRGTCCAI 304
Query: 298 NKVLMGRVPDRGGRPNEIEPPPPEMPPWQKRQEGGGGRGGWG 339
NKVLMG VPDRGGRPNE+EPP MP W+ R+E GG + WG
Sbjct: 305 NKVLMGNVPDRGGRPNELEPP---MPTWRSRREDGGPQ-CWG 342
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 118 bits (296), Expect = 9e-27
Identities = 65/108 (60%), Positives = 67/108 (62%), Gaps = 9/108 (8%)
Query: 331 GGGGRGGWGGGGGGGGRGGG--GGGGGRGGWGGG-GGGWGGGGGGGGGWGGGGGGGRGGF 387
G G RGG GG GGGG GGG GG G RGG GG GGG G GGG GGG+GGG GGG G
Sbjct: 486 GRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGG 545
Query: 388 QGRGDYGGRGG-YGGRGGYGGRGYGDPYGGG----GGGGGGGGGGGGY 430
G G GG GG YGG G GG G G YGGG GG GG GGG G+
Sbjct: 546 SGGGHSGGSGGNYGGGSGSGG-GSGGGYGGGSGSRGGSGGSHGGGSGF 592
Score = 108 bits (270), Expect = 9e-24
Identities = 66/117 (56%), Positives = 68/117 (58%), Gaps = 18/117 (15%)
Query: 331 GGGGRGGWGGGGGGGGRGGGGG--GGGRGGWGGGGGGWGGGGGGG--GGWGGGGGGGRGG 386
GGGG GG G GGG G RGG GG GGG G GG GGG+GGG GGG GG GGG GG GG
Sbjct: 498 GGGGSGG-GYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGG 556
Query: 387 FQGRGD---YGGRGGYGG----RGGYGG-RGYGDPYGGGGGGGGGG-----GGGGGY 430
G G G GGYGG RGG GG G G +GG GG GG G GGGY
Sbjct: 557 NYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGY 613
Score = 106 bits (265), Expect = 4e-23
Identities = 62/105 (59%), Positives = 64/105 (60%), Gaps = 9/105 (8%)
Query: 331 GGGGRGGWGGGGG-GGGRGGGGGGGGRGGWGGG-GGGWGGGGGGGGGWGGGGGGGRGGFQ 388
GG GG G GGG GGG GGG GGG GG GGG GG GG GGG G GGG GGG GG
Sbjct: 517 GGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGG-- 574
Query: 389 GRGDYGGRGG-YGGRGGYGGRGYGDPYGGG---GGGGGGGGGGGG 429
G G GG GG +GG G+GG G YGGG G GGG GGG G
Sbjct: 575 GSGSRGGSGGSHGGGSGFGGES-GGSYGGGEEASGSGGGYGGGSG 618
Score = 103 bits (256), Expect = 4e-22
Identities = 57/108 (52%), Positives = 59/108 (54%), Gaps = 7/108 (6%)
Query: 329 QEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGG-----GGGGG 383
+ G G+ G GG GG GG G G GG GG GGGG GG GGG G GG GGG G
Sbjct: 466 ESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSG 525
Query: 384 RGGFQGRGDYGGRGG--YGGRGGYGGRGYGDPYGGGGGGGGGGGGGGG 429
GG G G GG GG GG GG G G YGGG G GGG GGG G
Sbjct: 526 SGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYG 573
Score = 102 bits (254), Expect = 7e-22
Identities = 63/135 (46%), Positives = 70/135 (51%), Gaps = 35/135 (25%)
Query: 329 QEGGGGRGGWG---------------GGGGGGGR-----GGGGGGG---GRGGWGGGGGG 365
+ GGGG GG G GGGGGGGR G GGG GRGG G G
Sbjct: 13 RSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYS 72
Query: 366 WGGGGGG-------GGGWGGG----GGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPY 414
+GGG GG GGG+GGG GG GG+ G +GG G G GG+GG GYG +
Sbjct: 73 YGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGG-GYGSGF 131
Query: 415 GGGGGGGGGGGGGGG 429
GG GG GGG GGG G
Sbjct: 132 GGFGGFGGGAGGGDG 146
Score = 96.7 bits (239), Expect = 4e-20
Identities = 55/104 (52%), Positives = 59/104 (56%), Gaps = 11/104 (10%)
Query: 333 GGRGGWGGGGGG----GGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQ 388
GG+ + G G GGRGG GG GRG GG GG +GGGG G G GGG G RGG
Sbjct: 460 GGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGGGGSG--GGYGGGSGSRGG-- 515
Query: 389 GRGDYGGRGGYGG--RGGYGGRGYGDPYGGGGGGGGGGGGGGGY 430
G YGG G GG GGYGG G G + GG GGG GG GG Y
Sbjct: 516 SGGSYGGGSGSGGGSGGGYGG-GSGGGHSGGSGGGHSGGSGGNY 558
Score = 69.7 bits (169), Expect = 5e-12
Identities = 33/63 (52%), Positives = 35/63 (55%)
Query: 331 GGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGR 390
GG G GG GGG GGG G GG GG G G G GG GG GGG G GGG GG G+
Sbjct: 560 GGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGK 619
Query: 391 GDY 393
+
Sbjct: 620 SSH 622
Score = 64.3 bits (155), Expect = 2e-10
Identities = 44/93 (47%), Positives = 45/93 (48%), Gaps = 14/93 (15%)
Query: 347 RGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGG-YGGRGGY 405
R GGGGGGG G GG GGGGGGGR F YGG GRGG
Sbjct: 13 RSGGGGGGGLGS----GGSIRSSYSRFSSSGGGGGGGR--FSSSSGYGGGSSRVCGRGGG 66
Query: 406 GGRGYGDPYGGGGGGGG-----GGGGGGGYRRY 433
G GY YGGG GGG GGG GGG R +
Sbjct: 67 GSFGYS--YGGGSGGGFSASSLGGGFGGGSRGF 97
Score = 50.1 bits (118), Expect = 4e-06
Identities = 27/51 (52%), Positives = 28/51 (54%), Gaps = 6/51 (11%)
Query: 381 GGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGYR 431
G G+ G GRG GG G G RGG GG GGGG GGG GGG G R
Sbjct: 469 GAGKIGLGGRGGSGGSYGRGSRGGSGGSY------GGGGSGGGYGGGSGSR 513
Score = 33.5 bits (75), Expect = 0.39
Identities = 23/55 (41%), Positives = 23/55 (41%), Gaps = 11/55 (20%)
Query: 388 QGRGDYGGRGGYGGRGGYGGRG-----YGDPYGGGGGGGGG------GGGGGGYR 431
Q Y R G GG GG G G Y GGGGGGG G GGG R
Sbjct: 5 QFSSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSR 59
>gi|34740329 heterogeneous nuclear ribonucleoprotein A3 [Homo
sapiens]
Length = 378
Score = 117 bits (293), Expect = 2e-26
Identities = 66/110 (60%), Positives = 69/110 (62%), Gaps = 7/110 (6%)
Query: 326 QKRQEGGGGRGGWGGGGGGGGRGG--GGGGG--GRGGWGGGGGGWGGGGGGGGGWGGGGG 381
Q+ Q G RG GG G GRGG GGGGG GRGG GG GG+GGGGGG G GGG
Sbjct: 205 QEMQSAGSQRGRGGGSGNFMGRGGNFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGD 264
Query: 382 GGRGGFQG-RGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGY 430
GG GF G G+YGG GY RGGYGG G G YG GGG GGGGG GY
Sbjct: 265 GGYNGFGGDGGNYGGGPGYSSRGGYGGGGPG--YGNQGGGYGGGGGYDGY 312
Score = 113 bits (283), Expect = 3e-25
Identities = 66/116 (56%), Positives = 72/116 (62%), Gaps = 14/116 (12%)
Query: 327 KRQEGGG-----GRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGG----WGGGGGGGGGWG 377
+R GGG GRGG GGGGG G GG GGRGG+GGGGGG +GGG GG G+G
Sbjct: 213 QRGRGGGSGNFMGRGG-NFGGGGGNFGRGGNFGGRGGYGGGGGGSRGSYGGGDGGYNGFG 271
Query: 378 GGGG--GGRGGFQGRGDYGGRG-GYGGR-GGYGGRGYGDPYGGGGGGGGGGGGGGG 429
G GG GG G+ RG YGG G GYG + GGYGG G D Y GG GGG GGGG
Sbjct: 272 GDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGYDGYNEGGNFGGGNYGGGG 327
Score = 111 bits (277), Expect = 1e-24
Identities = 62/125 (49%), Positives = 66/125 (52%), Gaps = 24/125 (19%)
Query: 331 GGGGRGGWGGGGGG----GGRGGGGGGG----GRGGWGGGGGGWGGGGGGGGGWGGGGGG 382
GGG RG +GGG GG GG GG GGG RGG+GGGG G+G GGG GG GG G
Sbjct: 253 GGGSRGSYGGGDGGYNGFGGDGGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGYDGY 312
Query: 383 GRGGFQGRGDYGGRGGYGGRGGY----------------GGRGYGDPYGGGGGGGGGGGG 426
GG G G+YGG G Y G Y GGR G PYGGG G GGG GG
Sbjct: 313 NEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGPMKGGSFGGRSSGSPYGGGYGSGGGSGG 372
Query: 427 GGGYR 431
G R
Sbjct: 373 YGSRR 377
>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
Length = 589
Score = 116 bits (290), Expect = 5e-26
Identities = 68/107 (63%), Positives = 71/107 (66%), Gaps = 8/107 (7%)
Query: 332 GGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGG-GGWGGGGGGGRGGFQG- 389
GGG GG GGG GG RGGG GG GG+GG GG+GG GGG GG GG GG RGG+ G
Sbjct: 449 GGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGD 508
Query: 390 RGDYGG-RGGYGG---RGGYGG-RGYGDPYGGGGGGG-GGGGGGGGY 430
RG YGG RGGYGG RGGYGG RG G YGG GG GG GGGY
Sbjct: 509 RGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGY 555
Score = 112 bits (280), Expect = 7e-25
Identities = 68/119 (57%), Positives = 71/119 (59%), Gaps = 16/119 (13%)
Query: 328 RQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGG--GGGWGGGGGGG-----GGWGGGG 380
R GGG G GGG GG R GGG GG RGG GG GGG+GG GGG GG+GG
Sbjct: 428 RSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDR 487
Query: 381 GGGRGGFQG-----RGDYGG-RGGYGG-RGGYGGRGYGDPYGG--GGGGGGGGGGGGGY 430
GGG GG +G RG YGG RGGYGG RGGYGG YGG GGG G GG GGY
Sbjct: 488 GGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGY 546
Score = 105 bits (263), Expect = 6e-23
Identities = 74/130 (56%), Positives = 78/130 (60%), Gaps = 31/130 (23%)
Query: 332 GGGRGGWGG---GGGGGG-----------RGGGGGGGGR--GGWGGG-GGGWGG--GGGG 372
GG RGG+GG GGG GG R GGG GG R GG+GG GGG+GG GGG
Sbjct: 409 GGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGY 468
Query: 373 GGGWGGGGGGGRGGFQG--RGDYGG-RGGYGG-RGGYGG--RGYGDPYGGGGG----GGG 422
GG GGG GG RGG+ G G YGG RGGYGG RGGYGG GYG GG GG GG
Sbjct: 469 GGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGY 528
Query: 423 GG--GGGGGY 430
GG GGG GY
Sbjct: 529 GGDRGGGSGY 538
Score = 103 bits (258), Expect = 2e-22
Identities = 59/105 (56%), Positives = 61/105 (58%), Gaps = 8/105 (7%)
Query: 332 GGGRGGWGGGGGGGGRGGGGG------GGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRG 385
GGG GG GGG GG RGG GG GG RGG+GG GG+GG GG GG GG GG R
Sbjct: 465 GGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRS 524
Query: 386 GFQGRGDYGGRGGYGG--RGGYGGRGYGDPYGGGGGGGGGGGGGG 428
GD GG GYGG GGYGG G YGG GGG GG GG
Sbjct: 525 RGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGG 569
Score = 103 bits (257), Expect = 3e-22
Identities = 65/121 (53%), Positives = 69/121 (57%), Gaps = 19/121 (15%)
Query: 329 QEGGGGRGGWGG--GGGGGGRGGGGGGGGRGGWGG-----GGGGWGG-------GGGGGG 374
+ G GRGG GG GG GG R GGG GG R GG GGG+GG GG GG
Sbjct: 399 ERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGG 458
Query: 375 GWGGGGGGGRGGFQGRGDYGGRGGYGG--RGGYGG--RGYGDPYGG-GGGGGGGGGGGGG 429
G+GG GGG GG +G G G RGGYGG GGYGG GYG GG GG GG GG GG
Sbjct: 459 GYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGG 518
Query: 430 Y 430
Y
Sbjct: 519 Y 519
Score = 101 bits (251), Expect = 2e-21
Identities = 67/130 (51%), Positives = 72/130 (55%), Gaps = 17/130 (13%)
Query: 313 NEIEPPPPEMPPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGG--GGGGWGGGG 370
N+ P PE R GG RG G GG G RG GG GG RGG+GG GGG+GG
Sbjct: 374 NQCNEPRPE----DSRPSGGDFRGR-GYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDR 428
Query: 371 GGGGGWGGG-GGGGRGGFQGRGDYGG--RGGYGG--RGGYG---GRGYGDPYGGGGG--G 420
GGG+ G GGG GG + G YGG GGYGG GGYG G GYG GG GG G
Sbjct: 429 SSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRG 488
Query: 421 GGGGGGGGGY 430
GG GG GGY
Sbjct: 489 GGYGGDRGGY 498
Score = 100 bits (249), Expect = 3e-21
Identities = 72/136 (52%), Positives = 77/136 (56%), Gaps = 22/136 (16%)
Query: 316 EPPPPEMPP--WQKRQEGGGGRGGWGGGGGGGG-RGGGGG---GGGRGGWGGGGGGW--- 366
EP P + P R G GG G+ G GG GG RGG GG GGG GG GGG+
Sbjct: 378 EPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGD 437
Query: 367 --GGGGGG---GGGWGGGGGGGRGGFQGRGDYGG--RGGYGG-RGGYG---GRGYGDPYG 415
GGG GG GGG+GG GGG GG +G G YGG GGYGG RGGYG G GYG G
Sbjct: 438 RSGGGYGGDRSGGGYGGDRGGGYGGDRG-GGYGGDRGGGYGGDRGGYGGDRGGGYGGDRG 496
Query: 416 G-GGGGGGGGGGGGGY 430
G GG GG GG GGY
Sbjct: 497 GYGGDRGGYGGDRGGY 512
Score = 98.6 bits (244), Expect = 1e-20
Identities = 66/126 (52%), Positives = 70/126 (55%), Gaps = 31/126 (24%)
Query: 331 GGGGRGGWGG--GGGGGGRGGGGGGGGRGGWGGG-GGGWGGGGGGGGGWGGGGGGGRGGF 387
GG GG+GG GGG GG GGG GG RGG+GG GGG+GG GG GG GG GG RGG+
Sbjct: 453 GGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGY 512
Query: 388 QG-RGDYGG---RGGYGGR---------------------GGYGG-RGYGDPYGGGGGGG 421
G RG YGG RGGYGG GGYGG RG G YGG GG
Sbjct: 513 GGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGG--YGGDRGGY 570
Query: 422 GGGGGG 427
GG GG
Sbjct: 571 GGKMGG 576
Score = 77.0 bits (188), Expect = 3e-14
Identities = 56/133 (42%), Positives = 60/133 (45%), Gaps = 41/133 (30%)
Query: 340 GGGGGGGRGGGGGGGGRGGWGGGGGGWGGGG----------------------------- 370
GGG GGGR G GG GRGG+ G GG G
Sbjct: 324 GGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPED 383
Query: 371 --GGGGGWGGGGGGGRGGFQGRGDYGG-RGGYGG---RGGYG-----GRGY-GDPYGGGG 418
GG + G G GG G++GRG GG RGGYGG GGYG G GY GD GGG
Sbjct: 384 SRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGY 443
Query: 419 GGGGGGGGGGGYR 431
GG GGG GG R
Sbjct: 444 GGDRSGGGYGGDR 456
Score = 70.9 bits (172), Expect = 2e-12
Identities = 38/68 (55%), Positives = 41/68 (60%), Gaps = 6/68 (8%)
Query: 332 GGGRGGWGG----GGGGGGRGGGGGGGG--RGGWGGGGGGWGGGGGGGGGWGGGGGGGRG 385
GG RGG+GG GG GG RGGG G GG GG+GG G G GG GGG+GG GG G
Sbjct: 513 GGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGG 572
Query: 386 GFQGRGDY 393
GR DY
Sbjct: 573 KMGGRNDY 580
Score = 42.0 bits (97), Expect = 0.001
Identities = 23/50 (46%), Positives = 25/50 (50%)
Query: 384 RGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGYRRY 433
R G RG G +GG GRGGY G G G GG GG GG+R Y
Sbjct: 166 RYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDY 215
Score = 42.0 bits (97), Expect = 0.001
Identities = 24/56 (42%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
Query: 359 WGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGR--GDYGGRGGYGGRGGYGGRGYGD 412
+G G+GG GGG G GG GRG G GD GG +GG YG R D
Sbjct: 167 YGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDAD 222
Score = 39.3 bits (90), Expect = 0.007
Identities = 24/54 (44%), Positives = 27/54 (50%), Gaps = 6/54 (11%)
Query: 352 GGGGRGGWGGGGGGWGGGG---GGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGR 402
G RG G GGG G GG G G G GG RGGF+ ++GG YG R
Sbjct: 168 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFK---NFGGHRDYGPR 218
Score = 37.4 bits (85), Expect = 0.027
Identities = 22/51 (43%), Positives = 23/51 (45%)
Query: 346 GRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGR 396
G G GG +GG G GG G G G GG GG F G DYG R
Sbjct: 168 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPR 218
Score = 31.2 bits (69), Expect = 1.9
Identities = 17/43 (39%), Positives = 20/43 (46%)
Query: 329 QEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGG 371
++ G G GGG G GG G G G GG GG+ GG
Sbjct: 169 EDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGG 211
>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
Length = 592
Score = 116 bits (290), Expect = 5e-26
Identities = 68/107 (63%), Positives = 71/107 (66%), Gaps = 8/107 (7%)
Query: 332 GGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGG-GGWGGGGGGGRGGFQG- 389
GGG GG GGG GG RGGG GG GG+GG GG+GG GGG GG GG GG RGG+ G
Sbjct: 452 GGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGD 511
Query: 390 RGDYGG-RGGYGG---RGGYGG-RGYGDPYGGGGGGG-GGGGGGGGY 430
RG YGG RGGYGG RGGYGG RG G YGG GG GG GGGY
Sbjct: 512 RGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGY 558
Score = 112 bits (280), Expect = 7e-25
Identities = 68/119 (57%), Positives = 71/119 (59%), Gaps = 16/119 (13%)
Query: 328 RQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGG--GGGWGGGGGGG-----GGWGGGG 380
R GGG G GGG GG R GGG GG RGG GG GGG+GG GGG GG+GG
Sbjct: 431 RSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDR 490
Query: 381 GGGRGGFQG-----RGDYGG-RGGYGG-RGGYGGRGYGDPYGG--GGGGGGGGGGGGGY 430
GGG GG +G RG YGG RGGYGG RGGYGG YGG GGG G GG GGY
Sbjct: 491 GGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGY 549
Score = 105 bits (263), Expect = 6e-23
Identities = 74/130 (56%), Positives = 78/130 (60%), Gaps = 31/130 (23%)
Query: 332 GGGRGGWGG---GGGGGG-----------RGGGGGGGGR--GGWGGG-GGGWGG--GGGG 372
GG RGG+GG GGG GG R GGG GG R GG+GG GGG+GG GGG
Sbjct: 412 GGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGY 471
Query: 373 GGGWGGGGGGGRGGFQG--RGDYGG-RGGYGG-RGGYGG--RGYGDPYGGGGG----GGG 422
GG GGG GG RGG+ G G YGG RGGYGG RGGYGG GYG GG GG GG
Sbjct: 472 GGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGY 531
Query: 423 GG--GGGGGY 430
GG GGG GY
Sbjct: 532 GGDRGGGSGY 541
Score = 103 bits (258), Expect = 2e-22
Identities = 59/105 (56%), Positives = 61/105 (58%), Gaps = 8/105 (7%)
Query: 332 GGGRGGWGGGGGGGGRGGGGG------GGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRG 385
GGG GG GGG GG RGG GG GG RGG+GG GG+GG GG GG GG GG R
Sbjct: 468 GGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRS 527
Query: 386 GFQGRGDYGGRGGYGG--RGGYGGRGYGDPYGGGGGGGGGGGGGG 428
GD GG GYGG GGYGG G YGG GGG GG GG
Sbjct: 528 RGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGG 572
Score = 103 bits (257), Expect = 3e-22
Identities = 65/121 (53%), Positives = 69/121 (57%), Gaps = 19/121 (15%)
Query: 329 QEGGGGRGGWGG--GGGGGGRGGGGGGGGRGGWGG-----GGGGWGG-------GGGGGG 374
+ G GRGG GG GG GG R GGG GG R GG GGG+GG GG GG
Sbjct: 402 ERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGYGGDRSGGGYGGDRGG 461
Query: 375 GWGGGGGGGRGGFQGRGDYGGRGGYGG--RGGYGG--RGYGDPYGG-GGGGGGGGGGGGG 429
G+GG GGG GG +G G G RGGYGG GGYGG GYG GG GG GG GG GG
Sbjct: 462 GYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGG 521
Query: 430 Y 430
Y
Sbjct: 522 Y 522
Score = 101 bits (251), Expect = 2e-21
Identities = 67/130 (51%), Positives = 72/130 (55%), Gaps = 17/130 (13%)
Query: 313 NEIEPPPPEMPPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGG--GGGGWGGGG 370
N+ P PE R GG RG G GG G RG GG GG RGG+GG GGG+GG
Sbjct: 377 NQCNEPRPE----DSRPSGGDFRGR-GYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDR 431
Query: 371 GGGGGWGGG-GGGGRGGFQGRGDYGG--RGGYGG--RGGYG---GRGYGDPYGGGGG--G 420
GGG+ G GGG GG + G YGG GGYGG GGYG G GYG GG GG G
Sbjct: 432 SSGGGYSGDRSGGGYGGDRSGGGYGGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRG 491
Query: 421 GGGGGGGGGY 430
GG GG GGY
Sbjct: 492 GGYGGDRGGY 501
Score = 100 bits (249), Expect = 3e-21
Identities = 72/136 (52%), Positives = 77/136 (56%), Gaps = 22/136 (16%)
Query: 316 EPPPPEMPP--WQKRQEGGGGRGGWGGGGGGGG-RGGGGG---GGGRGGWGGGGGGW--- 366
EP P + P R G GG G+ G GG GG RGG GG GGG GG GGG+
Sbjct: 381 EPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGD 440
Query: 367 --GGGGGG---GGGWGGGGGGGRGGFQGRGDYGG--RGGYGG-RGGYG---GRGYGDPYG 415
GGG GG GGG+GG GGG GG +G G YGG GGYGG RGGYG G GYG G
Sbjct: 441 RSGGGYGGDRSGGGYGGDRGGGYGGDRG-GGYGGDRGGGYGGDRGGYGGDRGGGYGGDRG 499
Query: 416 G-GGGGGGGGGGGGGY 430
G GG GG GG GGY
Sbjct: 500 GYGGDRGGYGGDRGGY 515
Score = 98.6 bits (244), Expect = 1e-20
Identities = 66/126 (52%), Positives = 70/126 (55%), Gaps = 31/126 (24%)
Query: 331 GGGGRGGWGG--GGGGGGRGGGGGGGGRGGWGGG-GGGWGGGGGGGGGWGGGGGGGRGGF 387
GG GG+GG GGG GG GGG GG RGG+GG GGG+GG GG GG GG GG RGG+
Sbjct: 456 GGDRGGGYGGDRGGGYGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGY 515
Query: 388 QG-RGDYGG---RGGYGGR---------------------GGYGG-RGYGDPYGGGGGGG 421
G RG YGG RGGYGG GGYGG RG G YGG GG
Sbjct: 516 GGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGG--YGGDRGGY 573
Query: 422 GGGGGG 427
GG GG
Sbjct: 574 GGKMGG 579
Score = 77.0 bits (188), Expect = 3e-14
Identities = 56/133 (42%), Positives = 60/133 (45%), Gaps = 41/133 (30%)
Query: 340 GGGGGGGRGGGGGGGGRGGWGGGGGGWGGGG----------------------------- 370
GGG GGGR G GG GRGG+ G GG G
Sbjct: 327 GGGSGGGRRGRGGYRGRGGFQGRGGDPKSGDWVCPNPSCGNMNFARRNSCNQCNEPRPED 386
Query: 371 --GGGGGWGGGGGGGRGGFQGRGDYGG-RGGYGG---RGGYG-----GRGY-GDPYGGGG 418
GG + G G GG G++GRG GG RGGYGG GGYG G GY GD GGG
Sbjct: 387 SRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSGGGY 446
Query: 419 GGGGGGGGGGGYR 431
GG GGG GG R
Sbjct: 447 GGDRSGGGYGGDR 459
Score = 70.9 bits (172), Expect = 2e-12
Identities = 38/68 (55%), Positives = 41/68 (60%), Gaps = 6/68 (8%)
Query: 332 GGGRGGWGG----GGGGGGRGGGGGGGG--RGGWGGGGGGWGGGGGGGGGWGGGGGGGRG 385
GG RGG+GG GG GG RGGG G GG GG+GG G G GG GGG+GG GG G
Sbjct: 516 GGDRGGYGGDRSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGGGYGGDRGGYGG 575
Query: 386 GFQGRGDY 393
GR DY
Sbjct: 576 KMGGRNDY 583
Score = 42.0 bits (97), Expect = 0.001
Identities = 23/50 (46%), Positives = 25/50 (50%)
Query: 384 RGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGYRRY 433
R G RG G +GG GRGGY G G G GG GG GG+R Y
Sbjct: 169 RYGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDY 218
Score = 42.0 bits (97), Expect = 0.001
Identities = 24/56 (42%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
Query: 359 WGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGR--GDYGGRGGYGGRGGYGGRGYGD 412
+G G+GG GGG G GG GRG G GD GG +GG YG R D
Sbjct: 170 YGEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPRTDAD 225
Score = 39.3 bits (90), Expect = 0.007
Identities = 24/54 (44%), Positives = 27/54 (50%), Gaps = 6/54 (11%)
Query: 352 GGGGRGGWGGGGGGWGGGG---GGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGR 402
G RG G GGG G GG G G G GG RGGF+ ++GG YG R
Sbjct: 171 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFK---NFGGHRDYGPR 221
Score = 37.4 bits (85), Expect = 0.027
Identities = 22/51 (43%), Positives = 23/51 (45%)
Query: 346 GRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGR 396
G G GG +GG G GG G G G GG GG F G DYG R
Sbjct: 171 GEDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGGHRDYGPR 221
Score = 31.2 bits (69), Expect = 1.9
Identities = 17/43 (39%), Positives = 20/43 (46%)
Query: 329 QEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGG 371
++ G G GGG G GG G G G GG GG+ GG
Sbjct: 172 EDNRGYGGSQGGGRGRGGYDKDGRGPMTGSSGGDRGGFKNFGG 214
>gi|195972866 keratin 10 [Homo sapiens]
Length = 584
Score = 109 bits (273), Expect = 4e-24
Identities = 61/105 (58%), Positives = 62/105 (59%), Gaps = 6/105 (5%)
Query: 330 EGGGGRGGWGGGGGGGGRGGGGGGGGR--GGWGGGGGGWGGGGGGGGGWGGG-GGGGRGG 386
EG G GG GGG GGG GGG GGG GG GGG GG GGG GGG GGG GGG GG
Sbjct: 456 EGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGG 515
Query: 387 FQGRGDYGG--RGGY-GGRGGYGGRGYGDPYGGGGGGGGGGGGGG 428
G +GG GGY GG G GG GYG GGG GGG GGG
Sbjct: 516 GSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGG 560
Score = 108 bits (270), Expect = 9e-24
Identities = 56/97 (57%), Positives = 56/97 (57%), Gaps = 2/97 (2%)
Query: 334 GRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDY 393
G G GGGG GGG GGG GGG G G GGG GGG GG G G GGG GG G G Y
Sbjct: 455 GEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSG-GGY 513
Query: 394 GGRGGYGGRGGYGGRGYGD-PYGGGGGGGGGGGGGGG 429
GG GG GG GYG GGGGGG GGG GGG
Sbjct: 514 GGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGG 550
Score = 107 bits (266), Expect = 3e-23
Identities = 56/106 (52%), Positives = 57/106 (53%), Gaps = 8/106 (7%)
Query: 331 GGGGRGGW-------GGGGGGGGRGGGGGGGGRGGWGGG-GGGWGGGGGGGGGWGGGGGG 382
GGGGRGG GG GGG GGG GGG G GGG GGG GGG GGG+GGG
Sbjct: 460 GGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSS 519
Query: 383 GRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGG 428
G G G YGG GG GGYGG G GGG GGG GG
Sbjct: 520 GGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGG 565
Score = 97.4 bits (241), Expect = 2e-20
Identities = 49/98 (50%), Positives = 50/98 (51%), Gaps = 4/98 (4%)
Query: 332 GGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRG 391
GGG G G GGG GG GGG GGG G G GGG+GGG GG G GG GG G
Sbjct: 479 GGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSG-- 536
Query: 392 DYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGG 429
GG GGYGG GG G YGGG GG G
Sbjct: 537 --GGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSG 572
Score = 95.5 bits (236), Expect = 8e-20
Identities = 58/121 (47%), Positives = 64/121 (52%), Gaps = 18/121 (14%)
Query: 328 RQEGGGGRGGWGGGGG-------------GGGRGGGGGGGGRGGWGGGGGG-WGGGGGGG 373
R GGGG GG GGGGG GGG GG GG G GGG +GG GG
Sbjct: 15 RSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGY 74
Query: 374 GGWGGGGGGGRGGFQGRGDYGGR-GGYGGRGGYGGRGYGD-PYGGGG--GGGGGGGGGGG 429
GG GG GGG G G +GG GG G G +GG +G +GGGG GGG GGG GGG
Sbjct: 75 GGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGGFGGG 134
Query: 430 Y 430
+
Sbjct: 135 F 135
Score = 93.6 bits (231), Expect = 3e-19
Identities = 54/120 (45%), Positives = 62/120 (51%), Gaps = 16/120 (13%)
Query: 325 WQKRQEGGGGRGGWGGGGGG-------GGRGGGGGGGGRGGWGG--------GGGGWGGG 369
+ + GGGG GG GGGGG +G GGG GG+ G GGG +GG
Sbjct: 11 YSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGS 70
Query: 370 GGGGGGWGGGGGGGRGGFQGRGDYGGR-GGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGG 428
GG GG GG GGG G G +GG GG G G +GG +G GGGG GGGG GGG
Sbjct: 71 SGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGG 130
Score = 84.0 bits (206), Expect = 2e-16
Identities = 42/90 (46%), Positives = 45/90 (50%), Gaps = 3/90 (3%)
Query: 331 GGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGG---GGWGGGGGGGGGWGGGGGGGRGGF 387
GG GG+GGG GGG GGG GGG G GG GG+GGG GGGG G GGG GG
Sbjct: 492 GGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGS 551
Query: 388 QGRGDYGGRGGYGGRGGYGGRGYGDPYGGG 417
G YGG GG G+ G
Sbjct: 552 SSGGGYGGGSSSGGHKSSSSGSVGESSSKG 581
Score = 76.3 bits (186), Expect = 5e-14
Identities = 45/96 (46%), Positives = 53/96 (55%), Gaps = 18/96 (18%)
Query: 331 GGGGRGGWGGGGGG-GGRGGGGGGGGRGGWGGG--GGGWGGGGGGGGGWGGGGGGGRGGF 387
G G G +GG GG GG GG GGG RG +G GG +GG GGG +GGG GG
Sbjct: 60 GSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGG-SFGGGSFGGGSFGG---- 114
Query: 388 QGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGG 423
G +GG GG+GG G+G +GGG GG GG
Sbjct: 115 ---GSFGG-------GGFGGGGFGGGFGGGFGGDGG 140
Score = 72.4 bits (176), Expect = 7e-13
Identities = 36/78 (46%), Positives = 37/78 (47%)
Query: 331 GGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGR 390
GG GG+GGG GG GG GG GG GGGGG GGG GGG GGG G G G
Sbjct: 506 GGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGG 565
Query: 391 GDYGGRGGYGGRGGYGGR 408
G G G R
Sbjct: 566 HKSSSSGSVGESSSKGPR 583
Score = 63.2 bits (152), Expect = 5e-10
Identities = 34/63 (53%), Positives = 36/63 (57%), Gaps = 4/63 (6%)
Query: 331 GGGGRGGWG----GGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGG 386
GG RG +G GG GG GGG GGG G G GGG GGGG GGG+GGG GG G
Sbjct: 82 GGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGGGFGGGFGGDGGL 141
Query: 387 FQG 389
G
Sbjct: 142 LSG 144
Score = 55.5 bits (132), Expect = 9e-08
Identities = 34/72 (47%), Positives = 37/72 (51%), Gaps = 10/72 (13%)
Query: 368 GGGGGGGGWGGGGG-------GGRGGFQGRGDYGG-RGGYGGRGGYGGRGYGDPYGGGGG 419
GGGGGGGG GGGGG +G G GG GG RG GG +G GG
Sbjct: 17 GGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGG--SSGGY 74
Query: 420 GGGGGGGGGGYR 431
GG GG GGG +R
Sbjct: 75 GGLGGFGGGSFR 86
Score = 46.6 bits (109), Expect = 4e-05
Identities = 31/59 (52%), Positives = 32/59 (54%), Gaps = 17/59 (28%)
Query: 375 GWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGG---GGGY 430
G G GGGGRGG G +GG GYGG G GG G GGG GGG G GGGY
Sbjct: 455 GEGSSGGGGRGG----GSFGG--GYGG-GSSGG-------GSSGGGHGGGHGGSSGGGY 499
Score = 35.0 bits (79), Expect = 0.13
Identities = 14/20 (70%), Positives = 14/20 (70%)
Query: 410 YGDPYGGGGGGGGGGGGGGG 429
Y GGGGGGGG GGGGG
Sbjct: 11 YSSSRSGGGGGGGGCGGGGG 30
Score = 32.3 bits (72), Expect = 0.86
Identities = 18/43 (41%), Positives = 19/43 (44%), Gaps = 1/43 (2%)
Query: 391 GDYGGRGGYGGRGGYGGRGYGDPYGG-GGGGGGGGGGGGGYRR 432
G GG GG GG GG G GGG GG GG + R
Sbjct: 17 GGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSR 59
>gi|109255251 loricrin [Homo sapiens]
Length = 312
Score = 107 bits (267), Expect = 2e-23
Identities = 64/122 (52%), Positives = 67/122 (54%), Gaps = 13/122 (10%)
Query: 318 PPPEMPPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWG---GGGGGWGGGGGGGG 374
P P+ P + GGGG GG GGGG G GGGG GGG G G GGGG+ GGG GGG
Sbjct: 8 PTPQPPVDCVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGG 67
Query: 375 GWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGG------GGGG--GGG 426
GGGGGGG GG G GG Y G GG G G G GGGG GGGG GGG
Sbjct: 68 SSGGGGGGGIGGCGGGS--GGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGG 125
Query: 427 GG 428
G
Sbjct: 126 SG 127
Score = 106 bits (265), Expect = 4e-23
Identities = 62/120 (51%), Positives = 64/120 (53%), Gaps = 8/120 (6%)
Query: 316 EPPPPEMPPWQKRQEGGGGRGGWGGGGGG--GGRGGGGGGGGRGGWGGGGGGWGGGGGGG 373
+P P K GGGG GG GGGG G GG G GGG G G GGGG+ GGG GG
Sbjct: 7 QPTPQPPVDCVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGG 66
Query: 374 GGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGG----GGGGGGGG 429
G GGGGGGG GG G GG Y G GG G G G GGGG G GGGG GG
Sbjct: 67 GSSGGGGGGGIGGCGGGS--GGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGG 124
Score = 95.1 bits (235), Expect = 1e-19
Identities = 60/133 (45%), Positives = 63/133 (47%), Gaps = 34/133 (25%)
Query: 331 GGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGG----WGGGGGGGGGWG--------- 377
G G GG+ GGG GGG GGGGGGG GG GGG GG GGGG GGG G
Sbjct: 52 GYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGS 111
Query: 378 ----GGGGGGRGGFQGRGDYGGRGGYG--------GRGGYGG-----RGYGDPYGGGGGG 420
GGGG GG G GG G G G GG+ G + YG GG G
Sbjct: 112 GCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSG 171
Query: 421 GGGG----GGGGG 429
GG G GGGGG
Sbjct: 172 GGSGCFSSGGGGG 184
Score = 90.5 bits (223), Expect = 3e-18
Identities = 61/136 (44%), Positives = 63/136 (46%), Gaps = 33/136 (24%)
Query: 331 GGGGRGGWGGGGGG-------GGRGGGG------GGGGRGGWGGGGGGWGGGGGG----- 372
GGGG GG GGG GG GG GGG GGGG G + GGGG GGG G
Sbjct: 73 GGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSG 132
Query: 373 GGGWGGGGGG----GRGGFQGRG----DYGGRGGYGGRGGY-------GGRGYGDPYGGG 417
GGG GGG G G GGF G+ YGG G GG GG G Y GG
Sbjct: 133 GGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGG 192
Query: 418 GGGGGGGGGGGGYRRY 433
G G GGG GG Y
Sbjct: 193 GSGCGGGSSGGSGSGY 208
Score = 86.3 bits (212), Expect = 5e-17
Identities = 54/125 (43%), Positives = 56/125 (44%), Gaps = 24/125 (19%)
Query: 329 QEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWG----------- 377
Q GG G GGG G GGGGG G+ GGG G GGG GG G G
Sbjct: 159 QSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTS 218
Query: 378 -------GGGGGGRGGFQGRGDY---GGRGGYGGRGGYGGRGYGDPYGGGG---GGGGGG 424
GGG G GG G G + GG G G GG G G G GGG GGG G
Sbjct: 219 CAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSG 278
Query: 425 GGGGG 429
GGGGG
Sbjct: 279 GGGGG 283
Score = 74.3 bits (181), Expect = 2e-13
Identities = 50/123 (40%), Positives = 52/123 (42%), Gaps = 27/123 (21%)
Query: 332 GGGRGGWGGGGGGG------GRGGGGGGGGRGGWG--------------------GGGGG 365
GGG G + GGGGG G G G GGG GG G GGG
Sbjct: 171 GGGSGCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSS 230
Query: 366 WGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGG 425
GGG GG G + GGGGG G G G G G GG G G GGGGG GG
Sbjct: 231 GGGGSGGSGCFSSGGGGGSSGC-GGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGS 289
Query: 426 GGG 428
G G
Sbjct: 290 GSG 292
Score = 69.7 bits (169), Expect = 5e-12
Identities = 44/113 (38%), Positives = 45/113 (39%), Gaps = 21/113 (18%)
Query: 331 GGGGRGGWGGGGGGGGRGGGGGGGGR------------------GGWGGGGGGWGGGG-- 370
GGG G+ GGG G G G GG G GG GGGG GG G
Sbjct: 182 GGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCF 241
Query: 371 -GGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGG 422
GGGG G GGG G G G G G GG G G GG G G G
Sbjct: 242 SSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKG 294
Score = 61.6 bits (148), Expect = 1e-09
Identities = 34/72 (47%), Positives = 36/72 (50%), Gaps = 5/72 (6%)
Query: 323 PPWQKRQEGGGGRGGWG-----GGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWG 377
P + GGGG GG G GGGG G GGG G G G GGG GGG GGG G
Sbjct: 223 PSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGG 282
Query: 378 GGGGGGRGGFQG 389
G GG G +G
Sbjct: 283 GSSVGGSGSGKG 294
Score = 59.3 bits (142), Expect = 7e-09
Identities = 40/100 (40%), Positives = 40/100 (40%), Gaps = 17/100 (17%)
Query: 331 GGGGRGGWGGGG-----------------GGGGRGGGGGGGGRGGWGGGGGGWGGGGGGG 373
GGG GG G G GGG GGGG GG GGGGG G GGG
Sbjct: 197 GGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGS 256
Query: 374 GGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDP 413
G G G GG G G GG G G G G G P
Sbjct: 257 SGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGSGSGKGVP 296
Score = 45.1 bits (105), Expect = 1e-04
Identities = 26/54 (48%), Positives = 27/54 (50%), Gaps = 16/54 (29%)
Query: 377 GGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGY 430
GGGGGGG GG GG G +GG G G GG G G G GGGGY
Sbjct: 22 GGGGGGGSGG-------------GGCGFFGGGGSG---GGSSGSGCGYSGGGGY 59
>gi|109148552 keratin 3 [Homo sapiens]
Length = 628
Score = 107 bits (267), Expect = 2e-23
Identities = 56/97 (57%), Positives = 63/97 (64%), Gaps = 3/97 (3%)
Query: 331 GGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGG-GGGWGGGGGGGGGWGGGGG-GGRGGFQ 388
GG GG+GGG GG GGG G+GGG GGG+GGG G GGG+GG GG GG GGF
Sbjct: 73 GGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFGGAGGFGGAGGFG 132
Query: 389 GRGDYGGRGGYGGRGGYGGRG-YGDPYGGGGGGGGGG 424
G G +GG GG+GG GG+GG G G P G G GG GG
Sbjct: 133 GAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGG 169
Score = 91.7 bits (226), Expect = 1e-18
Identities = 54/97 (55%), Positives = 58/97 (59%), Gaps = 4/97 (4%)
Query: 336 GGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGG-GGGGGGGWG-GGGGGGRGGFQGRGDY 393
GG GG GGGR GG GG G G G GG GGG GGG G GGG GG GGF G G +
Sbjct: 73 GGSRAGGFGGGRSSCAFAGGYGGGFGSGYG-GGFGGGFGGGRGMGGGFGGAGGFGGAGGF 131
Query: 394 GGRGGYGGRGGYGGR-GYGDPYGGGGGGGGGGGGGGG 429
GG GG+GG GG+GG G+G P G GG G GG G
Sbjct: 132 GGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPG 168
Score = 88.6 bits (218), Expect = 1e-17
Identities = 56/124 (45%), Positives = 64/124 (51%), Gaps = 34/124 (27%)
Query: 331 GGGGRGGWGGGGGGGGRGG------GG----------GGGGRGGWGGG------GGGWGG 368
GG G G +G G GG G GG GG GG+GGG GG+GG
Sbjct: 36 GGAGGGAYGFRSGAGGFGSRSLYNLGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGG 95
Query: 369 GGGGG--GGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGG 426
G G G GG+GGG GGGRG G +GG GG+GG GG+GG GG GG GG GG
Sbjct: 96 GFGSGYGGGFGGGFGGGRGM---GGGFGGAGGFGGAGGFGG-------AGGFGGPGGFGG 145
Query: 427 GGGY 430
GG+
Sbjct: 146 SGGF 149
Score = 73.2 bits (178), Expect = 4e-13
Identities = 55/155 (35%), Positives = 66/155 (42%), Gaps = 16/155 (10%)
Query: 269 AHLLAAREDLSKIIRTSSGTSREKTACAIN-----KVLMGRVPDRGGRPNEIEPPPPEMP 323
A L A++DL++++R K A + K+L G G E P
Sbjct: 469 AALQQAKDDLARLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSG-----ECPSAVSI 523
Query: 324 PWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGG 383
GG+GGG GGG GG GGG GG G G G GGGGG GGG+GGG G
Sbjct: 524 SVVSSSTTSASAGGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGF 583
Query: 384 RGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGG 418
GG G G G R G G G+ GG
Sbjct: 584 SGG-SGFGSIS-----GARYGVSGGGFSSASNRGG 612
Score = 71.2 bits (173), Expect = 2e-12
Identities = 41/84 (48%), Positives = 45/84 (53%), Gaps = 7/84 (8%)
Query: 346 GRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGY 405
G GGG GGG G GG GGG+ GGG G G+G GGGGG GG G GG G+ G G+
Sbjct: 536 GGYGGGYGGGMG--GGLGGGFSAGGGSGSGFGRGGGGGIGG----GFGGGSSGFSGGSGF 589
Query: 406 GGRGYGDPYGGGGGGGGGGGGGGG 429
G G YG GGG GG
Sbjct: 590 GSIS-GARYGVSGGGFSSASNRGG 612
Score = 65.9 bits (159), Expect = 7e-11
Identities = 35/62 (56%), Positives = 37/62 (59%), Gaps = 5/62 (8%)
Query: 332 GGGRGGWGGGGGGGGRGGGGGGGGRGGWGG-----GGGGWGGGGGGGGGWGGGGGGGRGG 386
GGGRG GG GG GG GG GG GG GG+GG G GG+GG G G G G GG GG
Sbjct: 110 GGGRGMGGGFGGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGG 169
Query: 387 FQ 388
Q
Sbjct: 170 IQ 171
Score = 58.2 bits (139), Expect = 1e-08
Identities = 45/117 (38%), Positives = 50/117 (42%), Gaps = 22/117 (18%)
Query: 326 QKRQEGGGGRGGWGGGGG---GGGR-----GGGGGGGGRGGWGGGGGGWGG------GGG 371
Q + GGG G+ G G R GG GGG G+ G GG+G GG
Sbjct: 4 QASKTSGGGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGN 63
Query: 372 GGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGG 428
GG R G G GGR GGYGG G+G YGGG GG G GGG
Sbjct: 64 KSISISVAAGGSRAGGFG----GGRSSCAFAGGYGG-GFGSGYGGGFGG---GFGGG 112
Score = 45.8 bits (107), Expect = 8e-05
Identities = 27/61 (44%), Positives = 30/61 (49%), Gaps = 20/61 (32%)
Query: 370 GGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGG 429
GG GGG+GGG GGG GG G+ GG G G G GGGGG GGG
Sbjct: 536 GGYGGGYGGGMGGGLGG-----------GFSAGGGSGS---------GFGRGGGGGIGGG 575
Query: 430 Y 430
+
Sbjct: 576 F 576
Score = 38.9 bits (89), Expect = 0.009
Identities = 20/32 (62%), Positives = 21/32 (65%), Gaps = 3/32 (9%)
Query: 403 GGYGGRGYGDPYGGGGGGG--GGGGGGGGYRR 432
GGYGG GYG GGG GGG GGG G G+ R
Sbjct: 536 GGYGG-GYGGGMGGGLGGGFSAGGGSGSGFGR 566
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 107 bits (266), Expect = 3e-23
Identities = 51/88 (57%), Positives = 53/88 (60%), Gaps = 2/88 (2%)
Query: 343 GGGGRGGGGGGGGRGG--WGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYG 400
GGG RGGGGGG G GG +G GGG +G GGGGGGG G G GG G G YG GG G
Sbjct: 514 GGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGG 573
Query: 401 GRGGYGGRGYGDPYGGGGGGGGGGGGGG 428
G G YG Y GG GGGGGG GG
Sbjct: 574 GHGSYGSGSSSGGYRGGSGGGGGGSSGG 601
Score = 103 bits (257), Expect = 3e-22
Identities = 55/104 (52%), Positives = 56/104 (53%), Gaps = 5/104 (4%)
Query: 331 GGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGG--GGRGGFQ 388
GGG RGG GGG G GG G GGG G GGGGGG G G GG +G GGG G GG
Sbjct: 514 GGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGG 573
Query: 389 GRGDYGG---RGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGG 429
G G YG GGY G G GG G G GGG GG GG G
Sbjct: 574 GHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRG 617
Score = 103 bits (256), Expect = 4e-22
Identities = 55/104 (52%), Positives = 58/104 (55%), Gaps = 7/104 (6%)
Query: 332 GGGRGGWGGGG-----GGGGRG-GGGGGGGRGGWGGGGGGWGGGGGG-GGGWGGGGGGGR 384
GGG GG+G GG GGG G GGGGGGGRG +G GG +G GGG G G GGGG G
Sbjct: 519 GGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSY 578
Query: 385 GGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGG 428
G G Y G G GG G GGRG G GG GG G GG
Sbjct: 579 GSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGG 622
Score = 96.7 bits (239), Expect = 4e-20
Identities = 62/123 (50%), Positives = 67/123 (54%), Gaps = 35/123 (28%)
Query: 327 KRQEGGGGR-GGWGGGGGGGGRGGGGG-------------------GGGRGGWGGGGGGW 366
+R GGGGR GGGGG G GGG G GGGRG G GGG+
Sbjct: 37 RRSGGGGGRFSSCGGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGS--GFGGGY 94
Query: 367 GGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGG 426
GGGG GGGG+GGGG GG GG GG GG GG+G G G +GGGG GGGG GG
Sbjct: 95 GGGGFGGGGFGGGGFGG----------GGIGG-GGFGGFGSGGGG--FGGGGFGGGGYGG 141
Query: 427 GGG 429
G G
Sbjct: 142 GYG 144
Score = 92.4 bits (228), Expect = 7e-19
Identities = 48/98 (48%), Positives = 53/98 (54%), Gaps = 3/98 (3%)
Query: 332 GGGRGGWG-GGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGR 390
G G G +G GGGGGGGRG G GG +G GGG +G GGGGGG G G GG++G
Sbjct: 533 GSGGGSYGSGGGGGGGRGSYGSGG--SSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGG 590
Query: 391 GDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGG 428
GG G GGRG GG G G G GG GG
Sbjct: 591 SGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGG 628
Score = 91.3 bits (225), Expect = 2e-18
Identities = 57/116 (49%), Positives = 62/116 (53%), Gaps = 13/116 (11%)
Query: 325 WQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGG----------GGGG 374
+Q+R R GGGG GGGGG G GG G GG GGG
Sbjct: 27 YQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGR 86
Query: 375 GWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGY 430
G G GGG G GGF G G +GG GG+GG GG GG G+G GGGG GGGG GGGGY
Sbjct: 87 GSGFGGGYGGGGF-GGGGFGG-GGFGG-GGIGGGGFGGFGSGGGGFGGGGFGGGGY 139
Score = 77.4 bits (189), Expect = 2e-14
Identities = 41/86 (47%), Positives = 45/86 (52%), Gaps = 21/86 (24%)
Query: 348 GGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGG 407
GGG GGG GG+G GG +G GGG +G GGGGG GGRG YG
Sbjct: 514 GGGSRGGGGGGYGSGGSSYGSGGGS---YGSGGGGG----------------GGRGSYGS 554
Query: 408 RGYGDPYGGGGGGGGGGGGGGGYRRY 433
G YG GGG G GGGGGG+ Y
Sbjct: 555 GG--SSYGSGGGSYGSGGGGGGHGSY 578
Score = 41.6 bits (96), Expect = 0.001
Identities = 21/41 (51%), Positives = 21/41 (51%)
Query: 328 RQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGG 368
R GGG GG GG G GG GG GGRG GG GG
Sbjct: 588 RGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGG 628
Score = 32.0 bits (71), Expect = 1.1
Identities = 21/52 (40%), Positives = 22/52 (42%)
Query: 380 GGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGYR 431
GGG G G +Y R GG G GGGGG G GGG G R
Sbjct: 14 GGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSR 65
>gi|14043070 heterogeneous nuclear ribonucleoprotein A1 isoform b
[Homo sapiens]
Length = 372
Score = 105 bits (261), Expect = 1e-22
Identities = 61/124 (49%), Positives = 68/124 (54%), Gaps = 16/124 (12%)
Query: 321 EMPPWQKRQEGGGGRGGWGGGGGGGGRGG-----GGGGGGRGGWGG--GGGGWGGGG--- 370
EM Q G G G +GGG GGG G GG GRGG+GG GGGG+GG G
Sbjct: 185 EMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGY 244
Query: 371 ---GGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRG-GYGGRGYGDPYGGGGGGGGGGGG 426
G GG+GGGG G GG +G G G GYG +G GYGG G D Y GGGGG GGG
Sbjct: 245 NGFGNDGGYGGGGPGYSGGSRGYGS--GGQGYGNQGSGYGGSGSYDSYNNGGGGGFGGGS 302
Query: 427 GGGY 430
G +
Sbjct: 303 GSNF 306
Score = 90.9 bits (224), Expect = 2e-18
Identities = 53/116 (45%), Positives = 58/116 (50%), Gaps = 16/116 (13%)
Query: 331 GGGGRGGWGG-------------GGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWG 377
GGG GG+GG GG GG RGGGG GG G+ G G GG GGGG G+
Sbjct: 203 GGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGND-GGYGGGGPGYS 261
Query: 378 GGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGYRRY 433
GG G G QG G+ G GYGG G Y G G GGG G GGGG Y +
Sbjct: 262 GGSRGYGSGGQGYGNQG--SGYGGSGSYDSYNNGGGGGFGGGSGSNFGGGGSYNDF 315
Score = 85.1 bits (209), Expect = 1e-16
Identities = 53/116 (45%), Positives = 59/116 (50%), Gaps = 17/116 (14%)
Query: 331 GGGGRGGWGGGGGGGGRGGGGGGGGRG------GWGGGGGGWGGGGGGGGGWG------G 378
GGGG GG G G G G GG GGGG G G+G GG G+G G G GG G
Sbjct: 233 GGGGYGGSGDGYNGFGNDGGYGGGGPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNN 292
Query: 379 GGGGGRGGFQGRGDYGGRGGYGGRGGYGGR--GYGDPYGGGGGGGGGG--GGGGGY 430
GGGGG GG G ++GG G Y G Y + +G GG GG G GGGG Y
Sbjct: 293 GGGGGFGGGSG-SNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQY 347
Score = 83.6 bits (205), Expect = 3e-16
Identities = 51/122 (41%), Positives = 59/122 (48%), Gaps = 23/122 (18%)
Query: 331 GGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGG-------GGGGGWGGGGG-- 381
G G GG+GGGG G G G G G G+G G G+GG G GGGGG+GGG G
Sbjct: 246 GFGNDGGYGGGGPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGGGGGFGGGSGSN 305
Query: 382 -GGRGGFQGRGDYGGRGGYGG---RGGYGGRGYGDPYGGGG---------GGGGGGGGGG 428
GG G + G+Y + G G +GGR G PYGGGG GG GG
Sbjct: 306 FGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSG-PYGGGGQYFAKPRNQGGYGGSSSSS 364
Query: 429 GY 430
Y
Sbjct: 365 SY 366
Score = 75.1 bits (183), Expect = 1e-13
Identities = 46/96 (47%), Positives = 49/96 (51%), Gaps = 17/96 (17%)
Query: 355 GRGGWGGGGGGWGGGGGGGGGWGGGGG-GGRGGF---QGRGDYGGRG----GYGGRGGYG 406
GR G G GGG GGG GG +G GG GRGGF +G G YGG G G+G GGYG
Sbjct: 195 GRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGGYG 254
Query: 407 G---------RGYGDPYGGGGGGGGGGGGGGGYRRY 433
G RGYG G G G G GG G Y Y
Sbjct: 255 GGGPGYSGGSRGYGSGGQGYGNQGSGYGGSGSYDSY 290
Score = 63.2 bits (152), Expect = 5e-10
Identities = 42/108 (38%), Positives = 45/108 (41%), Gaps = 22/108 (20%)
Query: 332 GGGRGGWGGGGGGGGRGGGGGGGG-----RGGWGGGGGGWGGGGGGGGGWGGGGG----- 381
GG RG GG G G +G G GG G G GGG GG G GGGG G
Sbjct: 262 GGSRGYGSGGQGYGNQGSGYGGSGSYDSYNNGGGGGFGGGSGSNFGGGGSYNDFGNYNNQ 321
Query: 382 --------GGRGGFQGRGDYGGRGGY----GGRGGYGGRGYGDPYGGG 417
GG G + G YGG G Y +GGYGG YG G
Sbjct: 322 SSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYGSG 369
>gi|14043072 heterogeneous nuclear ribonucleoprotein A2/B1 isoform
B1 [Homo sapiens]
Length = 353
Score = 100 bits (248), Expect = 3e-21
Identities = 59/113 (52%), Positives = 67/113 (59%), Gaps = 11/113 (9%)
Query: 332 GGGRGGWGGGGGGGGRGGGGG-GGGRGGWGGGGGGWGGGGGG-GGGWGGGGGG--GRGGF 387
G G G+GGG GGG GG G GGGRGG+GGGG G+G GGG GGG+ GGG G G +
Sbjct: 241 GDGYNGYGGGPGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGGYDNYGGGNYGSGNY 300
Query: 388 QGRGDYGGR-GGYGGR--GGYGG-RGYGDPYGGGG---GGGGGGGGGGGYRRY 433
G+Y + YG G +GG R G PYGGG GG GG GG GG RY
Sbjct: 301 NDFGNYNQQPSNYGPMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGYGGRSRY 353
Score = 99.8 bits (247), Expect = 4e-21
Identities = 56/113 (49%), Positives = 61/113 (53%), Gaps = 14/113 (12%)
Query: 332 GGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGG----RGGF 387
G GRG G G GG GGG GG G+GGG GG+GGGG G G GGG GGG GG
Sbjct: 235 GSGRGFGDGYNGYGGGPGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGGYDNYGGGN 294
Query: 388 QGRGDYGGRGGYGGR---------GGYGG-RGYGDPYGGGGGGGGGGGGGGGY 430
G G+Y G Y + G +GG R G PYGGG G GG GG GGY
Sbjct: 295 YGSGNYNDFGNYNQQPSNYGPMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGY 347
Score = 91.3 bits (225), Expect = 2e-18
Identities = 57/111 (51%), Positives = 60/111 (54%), Gaps = 8/111 (7%)
Query: 321 EMPPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGG-RGGWGGGGGGWGGGGGGGGGWGGG 379
EM Q + G GG G+G GGGG G G G RGG G G G G G G G GG
Sbjct: 192 EMQEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGP 251
Query: 380 GGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGY 430
GGG GG G G GGRGGYGG GG GYG+ GGG GGG GGG Y
Sbjct: 252 GGGNFGGSPGYG--GGRGGYGG----GGPGYGNQ-GGGYGGGYDNYGGGNY 295
Score = 33.9 bits (76), Expect = 0.30
Identities = 17/40 (42%), Positives = 18/40 (45%)
Query: 319 PPEMPPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGG 358
P P + GG G GGG G GG GG GG GG
Sbjct: 310 PSNYGPMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGYGG 349
>gi|4504447 heterogeneous nuclear ribonucleoprotein A2/B1 isoform A2
[Homo sapiens]
Length = 341
Score = 100 bits (248), Expect = 3e-21
Identities = 59/113 (52%), Positives = 67/113 (59%), Gaps = 11/113 (9%)
Query: 332 GGGRGGWGGGGGGGGRGGGGG-GGGRGGWGGGGGGWGGGGGG-GGGWGGGGGG--GRGGF 387
G G G+GGG GGG GG G GGGRGG+GGGG G+G GGG GGG+ GGG G G +
Sbjct: 229 GDGYNGYGGGPGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGGYDNYGGGNYGSGNY 288
Query: 388 QGRGDYGGR-GGYGGR--GGYGG-RGYGDPYGGGG---GGGGGGGGGGGYRRY 433
G+Y + YG G +GG R G PYGGG GG GG GG GG RY
Sbjct: 289 NDFGNYNQQPSNYGPMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGYGGRSRY 341
Score = 99.8 bits (247), Expect = 4e-21
Identities = 56/113 (49%), Positives = 61/113 (53%), Gaps = 14/113 (12%)
Query: 332 GGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGG----RGGF 387
G GRG G G GG GGG GG G+GGG GG+GGGG G G GGG GGG GG
Sbjct: 223 GSGRGFGDGYNGYGGGPGGGNFGGSPGYGGGRGGYGGGGPGYGNQGGGYGGGYDNYGGGN 282
Query: 388 QGRGDYGGRGGYGGR---------GGYGG-RGYGDPYGGGGGGGGGGGGGGGY 430
G G+Y G Y + G +GG R G PYGGG G GG GG GGY
Sbjct: 283 YGSGNYNDFGNYNQQPSNYGPMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGY 335
Score = 91.3 bits (225), Expect = 2e-18
Identities = 57/111 (51%), Positives = 60/111 (54%), Gaps = 8/111 (7%)
Query: 321 EMPPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGG-RGGWGGGGGGWGGGGGGGGGWGGG 379
EM Q + G GG G+G GGGG G G G RGG G G G G G G G GG
Sbjct: 180 EMQEVQSSRSGRGGNFGFGDSRGGGGNFGPGPGSNFRGGSDGYGSGRGFGDGYNGYGGGP 239
Query: 380 GGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGY 430
GGG GG G G GGRGGYGG GG GYG+ GGG GGG GGG Y
Sbjct: 240 GGGNFGGSPGYG--GGRGGYGG----GGPGYGNQ-GGGYGGGYDNYGGGNY 283
Score = 33.9 bits (76), Expect = 0.30
Identities = 17/40 (42%), Positives = 18/40 (45%)
Query: 319 PPEMPPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGG 358
P P + GG G GGG G GG GG GG GG
Sbjct: 298 PSNYGPMKSGNFGGSRNMGGPYGGGNYGPGGSGGSGGYGG 337
>gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo
sapiens]
Length = 305
Score = 99.0 bits (245), Expect = 7e-21
Identities = 57/110 (51%), Positives = 62/110 (56%), Gaps = 16/110 (14%)
Query: 333 GGRGGWGGGGG----GGGRGGGGGGGGRGGWGGGGGG----WGGGGGGGGGWGGGGGGGR 384
GGRGG G GGG G +GGGGG GG+GGGGGG +GGGGGG G G G
Sbjct: 193 GGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGGGGGSSYGGSDYGNGF 252
Query: 385 GGF----QGRGDYG----GRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGG 426
GGF Q + YG G GG GG +GGR PY GG GGGGG GG
Sbjct: 253 GGFGSYSQHQSSYGPMKSGGGGGGGGSSWGGRSNSGPYRGGYGGGGGYGG 302
Score = 98.6 bits (244), Expect = 1e-20
Identities = 59/128 (46%), Positives = 63/128 (49%), Gaps = 23/128 (17%)
Query: 324 PWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGW----GGGGGGGGGWGGG 379
P + GGGG G GG GGRG GGG G GGGGG+ G GGGGGGG+
Sbjct: 175 PKEDIYSGGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAY 234
Query: 380 GGGGRGGFQGRGDYGGRGGYGGRGGYGGR--GYGDPYGGGGGGGGGG------------- 424
GGGG G G DYG G+GG G Y YG GGGGGGGG
Sbjct: 235 GGGGGGSSYGGSDYGN--GFGGFGSYSQHQSSYGPMKSGGGGGGGGSSWGGRSNSGPYRG 292
Query: 425 --GGGGGY 430
GGGGGY
Sbjct: 293 GYGGGGGY 300
Score = 97.4 bits (241), Expect = 2e-20
Identities = 61/119 (51%), Positives = 65/119 (54%), Gaps = 24/119 (20%)
Query: 331 GGGG----RGGWGGGGGGGGR-------GGGGGGGGRGGWGGGGGG----WGGGGGGGGG 375
GGGG RGG GG G GGGR GGGGG GG+GGGGGG +GGGGGG
Sbjct: 184 GGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGGGGGSSY 243
Query: 376 WGGGGGGGRGGF----QGRGDYG----GRGGYGGRGGYGGRGYGDPYGGG-GGGGGGGG 425
G G G GGF Q + YG G GG GG +GGR PY GG GGGGG GG
Sbjct: 244 GGSDYGNGFGGFGSYSQHQSSYGPMKSGGGGGGGGSSWGGRSNSGPYRGGYGGGGGYGG 302
Score = 77.0 bits (188), Expect = 3e-14
Identities = 45/95 (47%), Positives = 51/95 (53%), Gaps = 14/95 (14%)
Query: 330 EGGGGRGGWGGGGGGGGRGG-GGGGGGRGGWGGGGGGWGGGGGGGGGW------------ 376
+GGGG GG GGGG GG GGG GG GG +G G GG G +
Sbjct: 211 KGGGGGYNSYGGYGGGGGGGYNAYGGGGGGSSYGGSDYGNGFGGFGSYSQHQSSYGPMKS 270
Query: 377 GGGGGGGRGGFQGRGDYGG-RGGYGGRGGYGGRGY 410
GGGGGGG + GR + G RGGYGG GGYGG +
Sbjct: 271 GGGGGGGGSSWGGRSNSGPYRGGYGGGGGYGGSSF 305
Score = 56.6 bits (135), Expect = 4e-08
Identities = 34/62 (54%), Positives = 34/62 (54%), Gaps = 14/62 (22%)
Query: 377 GGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGY-GDPYGGGGG----GGGGGGGGGGYR 431
GGGGGG R RGG GGRG GGR G GGGGG GG GGGGGGGY
Sbjct: 182 GGGGGGSRSS---------RGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYN 232
Query: 432 RY 433
Y
Sbjct: 233 AY 234
Score = 42.0 bits (97), Expect = 0.001
Identities = 22/46 (47%), Positives = 26/46 (56%), Gaps = 3/46 (6%)
Query: 325 WQKRQEGGGGRGGWGGGGGGGGRGGGGGGGG--RGGWGGGGGGWGG 368
+ + Q G GGGGGGG GG G RGG+ GGGGG+GG
Sbjct: 258 YSQHQSSYGPMKSGGGGGGGGSSWGGRSNSGPYRGGY-GGGGGYGG 302
Score = 39.3 bits (90), Expect = 0.007
Identities = 19/36 (52%), Positives = 20/36 (55%), Gaps = 1/36 (2%)
Query: 324 PWQKRQEGGGGRGGWGGGGGGGG-RGGGGGGGGRGG 358
P + GGGG WGG G RGG GGGGG GG
Sbjct: 267 PMKSGGGGGGGGSSWGGRSNSGPYRGGYGGGGGYGG 302
>gi|12056465 fibrillarin [Homo sapiens]
Length = 321
Score = 94.0 bits (232), Expect = 2e-19
Identities = 49/82 (59%), Positives = 53/82 (64%), Gaps = 2/82 (2%)
Query: 323 PPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGG 382
P + R G GGRGG+G GG GGRGG GGG GRGG G G GGGGGGGGG GG GGG
Sbjct: 3 PGFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGG 62
Query: 383 G--RGGFQGRGDYGGRGGYGGR 402
G GG +GRG G RG G+
Sbjct: 63 GFHSGGNRGRGRGGKRGNQSGK 84
Score = 80.5 bits (197), Expect = 3e-15
Identities = 46/77 (59%), Positives = 48/77 (62%), Gaps = 10/77 (12%)
Query: 341 GGGGGGRGGGGGGGGRGGWGGGGGGWGGGG-------GGGGGWGGGGGGGR--GGFQGRG 391
GGG GGRGG G GGRGG GG GGG G GG GGGGG GGGGGGGR GGF G
Sbjct: 9 GGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRGGGGFHSGG 68
Query: 392 DYGGRGGYGGRGGYGGR 408
+ GRG G RG G+
Sbjct: 69 N-RGRGRGGKRGNQSGK 84
Score = 76.3 bits (186), Expect = 5e-14
Identities = 36/52 (69%), Positives = 37/52 (71%)
Query: 378 GGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGG 429
GGG GGRGGF RG GGRGG+GG G GG G GGGGGGGGGGGGG G
Sbjct: 9 GGGFGGRGGFGDRGGRGGRGGFGGGRGRGGGFRGRGRGGGGGGGGGGGGGRG 60
Score = 75.9 bits (185), Expect = 7e-14
Identities = 46/79 (58%), Positives = 50/79 (63%), Gaps = 8/79 (10%)
Query: 350 GGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRG 409
GGG GGRGG+G GG GG GG+GGG G G GGF+GRG GG GG GG GG GGRG
Sbjct: 9 GGGFGGRGGFGDRGGR-----GGRGGFGGGRGRG-GGFRGRGRGGGGGG-GGGGG-GGRG 60
Query: 410 YGDPYGGGGGGGGGGGGGG 428
G + GG G G GG G
Sbjct: 61 GGGFHSGGNRGRGRGGKRG 79
Score = 73.9 bits (180), Expect = 3e-13
Identities = 40/73 (54%), Positives = 45/73 (61%), Gaps = 12/73 (16%)
Query: 358 GWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGG 417
G+ GGG+GG GG G G GG GG GG +GRG GG+ GRG GG GGG
Sbjct: 4 GFSPRGGGFGGRGGFGDRGGRGGRGGFGGGRGRG-----GGFRGRGRGGG-------GGG 51
Query: 418 GGGGGGGGGGGGY 430
GGGGGGG GGGG+
Sbjct: 52 GGGGGGGRGGGGF 64
>gi|47132620 keratin 2 [Homo sapiens]
Length = 639
Score = 93.6 bits (231), Expect = 3e-19
Identities = 54/103 (52%), Positives = 58/103 (56%), Gaps = 15/103 (14%)
Query: 332 GGGRGGWGGGGGG-------GG--------RGGGGGGGGRGGWGGGGGGWGGGGGGGGGW 376
GGG GG+GGGG G GG GGGGG G GG+GG GGG+GGG GGG
Sbjct: 47 GGGGGGFGGGGFGSRSLVGLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGS 106
Query: 377 GGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGG 419
G GGG GG G G +GG GG GG GG GG G P G GG
Sbjct: 107 GFSGGGFGGGGFGGGRFGGFGGPGGVGGLGGPGGFGPGGYPGG 149
Score = 89.7 bits (221), Expect = 5e-18
Identities = 96/340 (28%), Positives = 144/340 (42%), Gaps = 46/340 (13%)
Query: 120 LSTELQASQILQNKKHKNSQLDKNSEVYQEVQAMFDT---LGIPKSTTSDIPHMLNQVES 176
+ ELQ+ L N++ + ++ ++E+ Q Q++ DT L + S D+ ++ +V++
Sbjct: 295 IKVELQSKVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKA 354
Query: 177 KVKDILSKVQKN-----HVGKPLLKMDLNSEQAEQLERINDALSCEYECRRRMLMKRLDV 231
+ ++I + ++ H L++ + + L+ I +S E R +++RL
Sbjct: 355 QYEEIAQRSKEEAEALYHSKYEELQVTVG-RHGDSLKEIKIEIS---ELNR--VIQRLQG 408
Query: 232 TVQSFGWSDRAKVKTDDIARIYQPKRYALSP---KTTITMAHLLAAREDLSKIIRTSSGT 288
+ + K D IA Q +AL K L A+EDL++++R
Sbjct: 409 EIAHV--KKQCKNVQDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQEL 466
Query: 289 SREKTACAIN-----KVLMGRVPDRGGRPNE-----IEPPPPEMPPWQKRQEGG-GGRGG 337
K A + K+L G G + + K GG GGRG
Sbjct: 467 MNVKLALDVEIATYRKLLEGEECRMSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGS 526
Query: 338 WGGGG--------GGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQG 389
GGG G GGR G GG GG GGG+G GGG GG +G GGG G G
Sbjct: 527 SSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISG 586
Query: 390 RGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGG 429
GGYG GG G G GG GGG G GGGG
Sbjct: 587 -------GGYGSGGGKHSSG-GGSRGGSSSGGGYGSGGGG 618
Score = 87.0 bits (214), Expect = 3e-17
Identities = 61/147 (41%), Positives = 65/147 (44%), Gaps = 51/147 (34%)
Query: 327 KRQEGGGGRGGWGG-------------------------GGGGGGRGGGG---------- 351
K + GGG GG+ G GGGGGG GGGG
Sbjct: 8 KSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLG 67
Query: 352 ----------GGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGR-GGYG 400
GGGG G GG GG GGG GGG +GGG G GGF G G GGR GG+G
Sbjct: 68 GTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFG 127
Query: 401 GRGGYGGRGYGDPYGGGGGGGGGGGGG 427
G GG GG G G GG G GG GG
Sbjct: 128 GPGGVGGLG-----GPGGFGPGGYPGG 149
Score = 85.9 bits (211), Expect = 7e-17
Identities = 60/136 (44%), Positives = 65/136 (47%), Gaps = 39/136 (28%)
Query: 334 GRGGWGGGGGGGGRGGGGGGGGR----------GGWGGGGGGWGGGG------------- 370
GRGG GGG G G GG GGGGGG+GGGG
Sbjct: 11 GRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGGTK 70
Query: 371 -------GGGGGWGGGGG-GGR-GGFQGRGDYGG-----RGGYGGRGGYGGR--GYGDPY 414
GGGGG+G GG GGR GGF G +GG GG+GG G GGR G+G P
Sbjct: 71 SISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGGPG 130
Query: 415 GGGGGGGGGGGGGGGY 430
G GG GG GG G GGY
Sbjct: 131 GVGGLGGPGGFGPGGY 146
Score = 83.2 bits (204), Expect = 4e-16
Identities = 50/111 (45%), Positives = 57/111 (51%), Gaps = 29/111 (26%)
Query: 347 RGGGGGGGGRGGWGGGGGGWGGG--------------GGGGGGWGGGGGGGR-----GGF 387
RG GGGGGG G+ G GG GGGGGG+GGGG G R GG
Sbjct: 10 RGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGGT 69
Query: 388 Q--------GRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGY 430
+ G G +G GG+GGRG GG G G +GGG G GGG GGGG+
Sbjct: 70 KSISISVAGGGGGFGAAGGFGGRG--GGFGGGSSFGGGSGFSGGGFGGGGF 118
Score = 79.0 bits (193), Expect = 8e-15
Identities = 45/85 (52%), Positives = 46/85 (54%), Gaps = 6/85 (7%)
Query: 333 GGRGGWGGGGG--GGGRGGGGGGGGRGGWGGGGGGW---GGGGGGGGGWGGGGGGGRGGF 387
G RGG GGGG GGG G GGG GGR G GGG G GGG G GGG GGG RGG
Sbjct: 547 GSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGS 606
Query: 388 QGRGDYG-GRGGYGGRGGYGGRGYG 411
G YG G GG G G +G
Sbjct: 607 SSGGGYGSGGGGSSSVKGSSGEAFG 631
Score = 76.3 bits (186), Expect = 5e-14
Identities = 44/100 (44%), Positives = 47/100 (47%), Gaps = 9/100 (9%)
Query: 331 GGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGR 390
G GGR GG GGG GGG G G GG GG +G GGG GG GGG G GG +
Sbjct: 540 GSGGRQSGSRGGSGGGGSISGGGYGSG--GGSGGRYGSGGGSKGGSISGGGYGSGGGKHS 597
Query: 391 GDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGY 430
G RGG GGYG GGGG G G +
Sbjct: 598 SGGGSRGGSSSGGGYGS-------GGGGSSSVKGSSGEAF 630
Score = 47.0 bits (110), Expect = 3e-05
Identities = 33/72 (45%), Positives = 33/72 (45%), Gaps = 12/72 (16%)
Query: 331 GGGGRGGWGGG-------GGGGGRGGG---GGGGGRGGW--GGGGGGWGGGGGGGGGWGG 378
G GGR G GGG GGG G GGG GGG RGG GGG G GGG G G
Sbjct: 568 GSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSGGGGSSSVKGSSG 627
Query: 379 GGGGGRGGFQGR 390
G F R
Sbjct: 628 EAFGSSVTFSFR 639
>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
[Homo sapiens]
Length = 526
Score = 92.0 bits (227), Expect = 9e-19
Identities = 55/118 (46%), Positives = 62/118 (52%), Gaps = 21/118 (17%)
Query: 319 PPEMPPWQKRQEGGGGRGGWGGGGG-----------GGGRGGG------GGGGGRGGWG- 360
PP+ Q + G GG GGGGG GGG GGG GGGG GG+G
Sbjct: 151 PPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQ 210
Query: 361 --GGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGG 416
GG G GG GGGGGG GGG GG++ RG GGRGG GG GG RG + +GG
Sbjct: 211 QDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGG-SDRGGFNKFGG 267
Score = 90.9 bits (224), Expect = 2e-18
Identities = 63/132 (47%), Positives = 64/132 (48%), Gaps = 36/132 (27%)
Query: 331 GGGGRGGWGGGG--GGGGRGGGG-GGGGRGGWGGGGGGWGGGGGGGGGW----------- 376
GG GRGG G GG G GG GGGG GGGGRGG+ GGGG GGG G W
Sbjct: 379 GGNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGG-GGGQQRAGDWKCPNPTCENMN 437
Query: 377 -------------------GGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGG 417
GG GG GG G GGRGGY RGGY GRG GD G
Sbjct: 438 FSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGY-DRGGYRGRG-GDRGGFR 495
Query: 418 GGGGGGGGGGGG 429
GG GGG GG G
Sbjct: 496 GGRGGGDRGGFG 507
Score = 85.9 bits (211), Expect = 7e-17
Identities = 54/129 (41%), Positives = 66/129 (51%), Gaps = 19/129 (14%)
Query: 321 EMPPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWG-------GGGGGG 373
+ P + +Q+ G + + G G + G GG GGGGG +G GGG G
Sbjct: 132 QQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSG 191
Query: 374 GGWGG---GGGGGRGGFQGRGDYG--GRGGYGGRGGYGGRGYG------DPYGGGGGGGG 422
GG+G GGGG GG+ G+ D G GRGG GG GG GG GY +P G GGG GG
Sbjct: 192 GGYGNQDQSGGGGSGGY-GQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGG 250
Query: 423 GGGGGGGYR 431
GG GG R
Sbjct: 251 RGGMGGSDR 259
Score = 73.6 bits (179), Expect = 3e-13
Identities = 45/89 (50%), Positives = 48/89 (53%), Gaps = 12/89 (13%)
Query: 331 GGGGRGGWG-----GGGGGGG-----RGGGGGGGGRGGWGGGGGGWGGGGGGGGGWG-GG 379
GGG GG+G GGGG GG RGG G GG GG GGGGGG+ GG G GG
Sbjct: 187 GGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNRSSGGYEPRGRGG 246
Query: 380 GGGGRGGFQGRGDYGGRGGYGGRGGYGGR 408
G GGRGG G D GG +GG G R
Sbjct: 247 GRGGRGG-MGGSDRGGFNKFGGPRDQGSR 274
Score = 68.9 bits (167), Expect = 8e-12
Identities = 42/80 (52%), Positives = 45/80 (56%), Gaps = 10/80 (12%)
Query: 329 QEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGG----GGGW--GGGGGGGGGWGGGGGG 382
Q GGGG GG+G GG RG GG GGG GG GGG GG+ G GGG GG GG GG
Sbjct: 199 QSGGGGSGGYGQQDRGG-RGRGGSGGGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGS 257
Query: 383 GRGGFQGRGDYGGRGGYGGR 402
RGGF +GG G R
Sbjct: 258 DRGGF---NKFGGPRDQGSR 274
Score = 68.6 bits (166), Expect = 1e-11
Identities = 50/109 (45%), Positives = 55/109 (50%), Gaps = 23/109 (21%)
Query: 342 GGGGGRGGGGGGG--GRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGY 399
GGG GRGG G GG GRGG+GGGG G GGG GG+ GGGGG GG Q GD+
Sbjct: 378 GGGNGRGGRGRGGPMGRGGYGGGGSG----GGGRGGFPSGGGGG-GGQQRAGDWKCPNPT 432
Query: 400 GGRGGYGGRGYGD------PYGGGGGGGG---GG-------GGGGGYRR 432
+ R + P G GGG GG GG GG GGY R
Sbjct: 433 CENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGGYDR 481
Score = 55.8 bits (133), Expect = 7e-08
Identities = 45/115 (39%), Positives = 47/115 (40%), Gaps = 50/115 (43%)
Query: 331 GGGGRGGW--GGGGGGG----------------------------------GRGGGGGG- 353
GGGGRGG+ GGGGGGG G GGG GG
Sbjct: 403 GGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGGPGGS 462
Query: 354 -----------GGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRG 397
GGRGG+ GG G GG GG GG GGG RGGF G G RG
Sbjct: 463 HMGGNYGDDRRGGRGGYDRGGYR-GRGGDRGGFRGGRGGGDRGGF-GPGKMDSRG 515
Score = 55.8 bits (133), Expect = 7e-08
Identities = 36/82 (43%), Positives = 42/82 (51%), Gaps = 10/82 (12%)
Query: 313 NEIEPPPPEMPPWQKRQEGGGGRGG-WGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGG 371
N+ + P P+ P GGG GG GG G R GG GG RGG+ G GG GG G
Sbjct: 445 NQCKAPKPDGP--------GGGPGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRG 496
Query: 372 GGGGWGGGGGGGRGGFQGRGDY 393
G GG G GG G G RG++
Sbjct: 497 GRGG-GDRGGFGPGKMDSRGEH 517
Score = 49.3 bits (116), Expect = 7e-06
Identities = 31/66 (46%), Positives = 33/66 (50%), Gaps = 18/66 (27%)
Query: 356 RGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYG 415
R + GGG GG G GG G GG GG GG GG GGRGG+ P G
Sbjct: 372 RADFNRGGGNGRGGRGRGGPMGRGGYGG----------GGSGG-GGRGGF-------PSG 413
Query: 416 GGGGGG 421
GGGGGG
Sbjct: 414 GGGGGG 419
Score = 40.0 bits (92), Expect = 0.004
Identities = 33/126 (26%), Positives = 41/126 (32%), Gaps = 21/126 (16%)
Query: 326 QKRQEGGGGRGGWGGGG-------------GGGGRGGGGGGGGRGGWGGGGGGWGGGGGG 372
Q +G G GG+G G G + G G +G G
Sbjct: 69 QSTPQGYGSTGGYGSSQSSQSSYGQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSG 128
Query: 373 GGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGG--------GG 424
GG + + + Y GYG + Y G GGGGG G GG
Sbjct: 129 SYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGGGGNYGQDQSSMSSGG 188
Query: 425 GGGGGY 430
G GGGY
Sbjct: 189 GSGGGY 194
>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
sapiens]
Length = 940
Score = 85.9 bits (211), Expect = 7e-17
Identities = 58/132 (43%), Positives = 62/132 (46%), Gaps = 16/132 (12%)
Query: 308 RGGRPNEIEPPPPEMPPWQKRQEGGGGRGGWGGGGGGGGRGGGGGG----GGRGGWGGGG 363
RGGR PPPP PP++ G RGG GGG GRGG GGG GG G G
Sbjct: 707 RGGRGGNEPPPPP--PPFR------GARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPG 758
Query: 364 GGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGG----GG 419
GG G G G GGG G G G G GG GG + G G G G G G
Sbjct: 759 GGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEG 818
Query: 420 GGGGGGGGGGYR 431
GGG G GGG+R
Sbjct: 819 PGGGMGAGGGHR 830
Score = 80.5 bits (197), Expect = 3e-15
Identities = 61/151 (40%), Positives = 64/151 (42%), Gaps = 31/151 (20%)
Query: 312 PNEIEPPPPEM---PPWQ---KRQEGGGGRGGWGGGGGGGGRGGGGGG------------ 353
P + PPPP P W GG RGG G G G RG GG G
Sbjct: 664 PRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFR 723
Query: 354 GGRGGWGGGGGGWGGGGGGGGGWGGGG-------GGGRGGFQGRGDYGGRGGYGGRGGYG 406
G RGG GGG G GG GGG GGGG GGG G G + G GG G G
Sbjct: 724 GARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRP 783
Query: 407 GRGYGDPYGGGG------GGGGGGGGGGGYR 431
G G GGGG G GGG GG G+R
Sbjct: 784 HEGPGGSMGGGGGHRPHEGPGGGISGGSGHR 814
Score = 58.9 bits (141), Expect = 9e-09
Identities = 50/125 (40%), Positives = 53/125 (42%), Gaps = 30/125 (24%)
Query: 337 GWGGGGGGGGRG-----GGGGGGGRGGWGGGGGGWGGG--------GGGGGGWGGGGGGG 383
G+ GG GG +G G GG G GG GG G GG W G G
Sbjct: 628 GFPPGGPGGPKGMQHFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPM 687
Query: 384 RGG------FQGRGDY-GGRGGYGG----------RGGYGGRGYGDPYGGGGGGGGGGGG 426
RGG G G Y GRGG GG RG GGR G P G GG GGG G
Sbjct: 688 RGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVG 747
Query: 427 GGGYR 431
GGG+R
Sbjct: 748 GGGHR 752
Score = 40.4 bits (93), Expect = 0.003
Identities = 44/146 (30%), Positives = 46/146 (31%), Gaps = 60/146 (41%)
Query: 309 GGRPNEIEPPPPEMPPWQKRQEGGGGRGGWGGG-----GGGGGRGGGGG-------GGGR 356
G RP+E P M + EG GG G GGG G GGG GG G GGG
Sbjct: 766 GHRPHE--GPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGM 823
Query: 357 GGWGGG------GGGWGGGGG--------------------------------------- 371
G GG GG GG GG
Sbjct: 824 GAGGGHRPHEGPGGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRGPPPHEHRGH 883
Query: 372 -GGGGWGGGGGGGRGGFQGRGDYGGR 396
G G GGG G GG GD R
Sbjct: 884 DGPGHGGGGHRGHDGGHSHGGDMSNR 909
Score = 38.1 bits (87), Expect = 0.016
Identities = 53/197 (26%), Positives = 60/197 (30%), Gaps = 76/197 (38%)
Query: 312 PNEIEPPPPEM-----------PPWQKRQEGGGGRGGWGGGGGGG-----GRGGGGGGGG 355
P EP PP++ P+ + E GG G G GG G G G
Sbjct: 509 PEPYEPIPPKLIPLDEECSMDETPYVETLEPGGSGGSPDGAGGSKLPPVLANLMGSMGAG 568
Query: 356 RGGWGGGGGGWG----------------------------------------GGGGGGGG 375
+G G GGGG G G G
Sbjct: 569 KGPQGPGGGGINVQEILTSIMGSPNSHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANG 628
Query: 376 WGGGGGGGRGGFQG---------RGDYGGRGGYGG----------RGGYG-GRGYGDPYG 415
+ GG GG G Q G +GG GG G RGG G GDP
Sbjct: 629 FPPGGPGGPKGMQHFPPGPGGPMPGPHGGPGGPVGPRLLGPPPPPRGGDPFWDGPGDPMR 688
Query: 416 GGGGGGGGGGGGGGYRR 432
GG GG G G G Y R
Sbjct: 689 GGPMRGGPGPGPGPYHR 705
>gi|100913206 DEAH (Asp-Glu-Ala-His) box polypeptide 9 [Homo sapiens]
Length = 1270
Score = 85.5 bits (210), Expect = 9e-17
Identities = 55/110 (50%), Positives = 60/110 (54%), Gaps = 10/110 (9%)
Query: 323 PPWQKRQEGGGG--RGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGG 380
PP R + G G RGG GGG G G GG G GG+GG + G G G G GG
Sbjct: 1161 PPKMARYDNGSGYRRGGSSYSGGGYGGGYSSGGYGSGGYGGSANSFRAGYGAGVG-GGYR 1219
Query: 381 GGGRGGFQGR--GDY-GGRGGYGGRGGY---GGRG-YGDPYGGGGGGGGG 423
G RGGF+G GDY G GGY G GG+ GGRG YG Y G G GGGG
Sbjct: 1220 GVSRGGFRGNSGGDYRGPSGGYRGSGGFQRGGGRGAYGTGYFGQGRGGGG 1269
Score = 53.5 bits (127), Expect = 4e-07
Identities = 40/86 (46%), Positives = 45/86 (52%), Gaps = 18/86 (20%)
Query: 331 GGGGRGGWGGG------GGGGGRGGGGGGGGRGGWGGGGGGW----GGGGGGGGGWGGGG 380
GG G GG+GG G G G GGG G RGG+ G GG GG G GG+
Sbjct: 1192 GGYGSGGYGGSANSFRAGYGAGVGGGYRGVSRGGFRGNSGGDYRGPSGGYRGSGGF--QR 1249
Query: 381 GGGRGGFQGRGDYG-GRGGYGGRGGY 405
GGGRG + G G +G GRGG GGY
Sbjct: 1250 GGGRGAY-GTGYFGQGRGG----GGY 1270
Score = 32.3 bits (72), Expect = 0.86
Identities = 17/30 (56%), Positives = 17/30 (56%), Gaps = 3/30 (10%)
Query: 404 GYGGRGYGDPYGGGGGGGG---GGGGGGGY 430
G G R G Y GGG GGG GG G GGY
Sbjct: 1170 GSGYRRGGSSYSGGGYGGGYSSGGYGSGGY 1199
>gi|153791670 keratin 76 [Homo sapiens]
Length = 638
Score = 85.1 bits (209), Expect = 1e-16
Identities = 52/120 (43%), Positives = 60/120 (50%), Gaps = 27/120 (22%)
Query: 335 RGGWGGGGGGGGRGGGGGGGGR----------------------GGWGGGGGGWGGGGGG 372
R G GGG G R G G G R GG+GGG G GG
Sbjct: 35 RSGGAGGGACGFRSGAGSFGSRSLYNLGSNKSISISVAAGSSRAGGFGGGRSSCGFAGGY 94
Query: 373 GGGWGGGGGGGRGGFQGRGD-YGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGG-GGGGY 430
GGG+GG GGG GG +G G +GG GG+GG GG+GG G +GG G GG GG G GG+
Sbjct: 95 GGGFGGSYGGGFGGGRGVGSGFGGAGGFGGAGGFGGPGV---FGGPGSFGGPGGFGPGGF 151
Score = 77.8 bits (190), Expect = 2e-14
Identities = 42/81 (51%), Positives = 46/81 (56%), Gaps = 4/81 (4%)
Query: 331 GGGGRGGWGGG----GGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGG 386
G GG+GGG G GG GGG GG GG+GGG G G GG GG G GG GG G
Sbjct: 74 GSSRAGGFGGGRSSCGFAGGYGGGFGGSYGGGFGGGRGVGSGFGGAGGFGGAGGFGGPGV 133
Query: 387 FQGRGDYGGRGGYGGRGGYGG 407
F G G +GG GG+G G GG
Sbjct: 134 FGGPGSFGGPGGFGPGGFPGG 154
Score = 59.7 bits (143), Expect = 5e-09
Identities = 47/143 (32%), Positives = 54/143 (37%), Gaps = 53/143 (37%)
Query: 339 GGGGGGGGRGGGGGGGGRGGWGGGGGGWGGG----------------------------- 369
G G GR G R GG GGG
Sbjct: 12 GRSQGFSGRSAVVSGSSRMSCVARSGGAGGGACGFRSGAGSFGSRSLYNLGSNKSISISV 71
Query: 370 --------------------GGGGGGWGGGGGGGRGGFQGRGD-YGGRGGYGGRGGYGGR 408
GG GGG+GG GGG GG +G G +GG GG+GG GG+GG
Sbjct: 72 AAGSSRAGGFGGGRSSCGFAGGYGGGFGGSYGGGFGGGRGVGSGFGGAGGFGGAGGFGGP 131
Query: 409 G-YGDP--YGGGGGGGGGGGGGG 428
G +G P +GG GG G GG GG
Sbjct: 132 GVFGGPGSFGGPGGFGPGGFPGG 154
Score = 57.0 bits (136), Expect = 3e-08
Identities = 39/103 (37%), Positives = 42/103 (40%), Gaps = 15/103 (14%)
Query: 341 GGGGGGRG--GGGGGGGRGGWGGG-----GGGWGGGGGGGGGWGGGGGGGRGGFQGRGDY 393
G G RG GG G G GG+ GG G+G GG G G+GG G GG G Y
Sbjct: 517 GSSGSSRGVFGGVSGSGSGGYKGGSSSSSSSGYGVSGGSGSGYGGVSSGSTGGRGSSGSY 576
Query: 394 -----GGRGGYGGRGGYGGRGYGDPYGG---GGGGGGGGGGGG 428
G R G G G G G GG G GGGG
Sbjct: 577 QSSSSGSRLGGAGSISVSHSGMGSSSGSIQTSGGSGYKSGGGG 619
Score = 55.5 bits (132), Expect = 9e-08
Identities = 37/106 (34%), Positives = 40/106 (37%), Gaps = 7/106 (6%)
Query: 332 GGGRGGWGG--GGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQG 389
G RG +GG G G GG GG G+G GG G G GG GG G G +Q
Sbjct: 520 GSSRGVFGGVSGSGSGGYKGGSSSSSSSGYGVSGGS-GSGYGGVSSGSTGGRGSSGSYQS 578
Query: 390 RGDYGGRGGYG----GRGGYGGRGYGDPYGGGGGGGGGGGGGGGYR 431
GG G G G GG G GGGG R
Sbjct: 579 SSSGSRLGGAGSISVSHSGMGSSSGSIQTSGGSGYKSGGGGSTSIR 624
Score = 49.7 bits (117), Expect = 5e-06
Identities = 33/103 (32%), Positives = 37/103 (35%), Gaps = 9/103 (8%)
Query: 332 GGGRGGWGGGGGGGGRGGGG-GGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGR 390
G G GG+ GG G G GG G+GG G GG G G + G R
Sbjct: 531 GSGSGGYKGGSSSSSSSGYGVSGGSGSGYGGVSSGSTGGRGSSGSYQSSSSGSR------ 584
Query: 391 GDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGYRRY 433
GG G G G GG G GGGG R+
Sbjct: 585 --LGGAGSISVSHSGMGSSSGSIQTSGGSGYKSGGGGSTSIRF 625
Score = 40.0 bits (92), Expect = 0.004
Identities = 26/72 (36%), Positives = 28/72 (38%), Gaps = 1/72 (1%)
Query: 331 GGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGG-GGGRGGFQG 389
G G GG G G GG G GG G G + G GG G G G G Q
Sbjct: 548 GYGVSGGSGSGYGGVSSGSTGGRGSSGSYQSSSSGSRLGGAGSISVSHSGMGSSSGSIQT 607
Query: 390 RGDYGGRGGYGG 401
G G + G GG
Sbjct: 608 SGGSGYKSGGGG 619
Score = 37.7 bits (86), Expect = 0.020
Identities = 22/65 (33%), Positives = 25/65 (38%), Gaps = 11/65 (16%)
Query: 367 GGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGG 426
G G G +GG G G GG++G GYG G G G G GG G
Sbjct: 517 GSSGSSRGVFGGVSGSGSGGYKGGSSSSSSSGYGVSG-----------GSGSGYGGVSSG 565
Query: 427 GGGYR 431
G R
Sbjct: 566 STGGR 570
>gi|4504445 heterogeneous nuclear ribonucleoprotein A1 isoform a
[Homo sapiens]
Length = 320
Score = 82.0 bits (201), Expect = 9e-16
Identities = 52/123 (42%), Positives = 61/123 (49%), Gaps = 19/123 (15%)
Query: 326 QKRQEGGGGRGGWGGGGGGGGR--GGGGGGGGRGGWGG--GGGGWGGGGGGGGGWGGGGG 381
Q+ + G G GG GGG GG G GG GRGG+GG GGGG+GG G G G+G G
Sbjct: 193 QRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGS 252
Query: 382 --GGRGGFQGRGDYGGRGGYGG---RGGYGGRGYGDPYGGGG---------GGGGGGGGG 427
GG G + G+Y + G G +GGR G PYGGGG GG GG
Sbjct: 253 NFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSG-PYGGGGQYFAKPRNQGGYGGSSSS 311
Query: 428 GGY 430
Y
Sbjct: 312 SSY 314
Score = 79.3 bits (194), Expect = 6e-15
Identities = 53/134 (39%), Positives = 62/134 (46%), Gaps = 22/134 (16%)
Query: 321 EMPPWQKRQEGGGGRGGWGGGGGGGGRGG-----GGGGGGRGGWGG--GGGGWGGGGGGG 373
EM Q G G G +GGG GGG G GG GRGG+GG GGGG+GG G G
Sbjct: 185 EMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGY 244
Query: 374 GGWGGGGG--GGRGGFQGRGDYGGR---------GGYGGR--GGYGGRG--YGDPYGGGG 418
G+G G GG G + G+Y + G +GGR G YGG G + P GG
Sbjct: 245 NGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSGPYGGGGQYFAKPRNQGG 304
Query: 419 GGGGGGGGGGGYRR 432
GG G R
Sbjct: 305 YGGSSSSSSYGSGR 318
Score = 64.7 bits (156), Expect = 2e-10
Identities = 35/70 (50%), Positives = 39/70 (55%), Gaps = 2/70 (2%)
Query: 365 GWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGG-RGGYGGRGYGDPYGGGGGGGGG 423
G G G GGG GG G GG F G++ GRGG+GG RGG G G GD Y G G G
Sbjct: 195 GRSGSGNFGGGRGG-GFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSN 253
Query: 424 GGGGGGYRRY 433
GGGG Y +
Sbjct: 254 FGGGGSYNDF 263
>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
[Homo sapiens]
Length = 2191
Score = 81.6 bits (200), Expect = 1e-15
Identities = 48/116 (41%), Positives = 52/116 (44%), Gaps = 15/116 (12%)
Query: 324 PWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGG 383
P R GGG GG GGGGGG G GGGGGG G GG G G GGGGGGG
Sbjct: 241 PGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGG-AGAGAVAAAAAAAAAAAGGGGGGG 299
Query: 384 RGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGG------GGGGGGGGGYRRY 433
G G GYG +G G G GGGG G GG++R+
Sbjct: 300 YG--------GSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRF 347
Score = 49.7 bits (117), Expect = 5e-06
Identities = 47/151 (31%), Positives = 54/151 (35%), Gaps = 35/151 (23%)
Query: 311 RPNEIEPPPPEM--PPWQKRQEGGGGRGGW--------GGGGG-----------GGGRGG 349
+P + + PP+M P + + G G G GGGGG G
Sbjct: 123 KPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPA 182
Query: 350 GGGGGGRGG--WGGGGGGWGGGGGGGGGWGGGGGGGRGGFQG---------RGDYGGRGG 398
GG GGR G + GG G G G G G
Sbjct: 183 SGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPG 242
Query: 399 YGGRGGYGGRGYGDPYGGGGGGGGGGGGGGG 429
Y G GG G G GGGGGG GGGGGGGG
Sbjct: 243 YSRPGAGGGGGGG---GGGGGGSGGGGGGGG 270
>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
[Homo sapiens]
Length = 2231
Score = 81.6 bits (200), Expect = 1e-15
Identities = 48/116 (41%), Positives = 52/116 (44%), Gaps = 15/116 (12%)
Query: 324 PWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGG 383
P R GGG GG GGGGGG G GGGGGG G GG G G GGGGGGG
Sbjct: 241 PGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGG-AGAGAVAAAAAAAAAAAGGGGGGG 299
Query: 384 RGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGG------GGGGGGGGGYRRY 433
G G GYG +G G G GGGG G GG++R+
Sbjct: 300 YG--------GSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRF 347
Score = 49.7 bits (117), Expect = 5e-06
Identities = 47/151 (31%), Positives = 54/151 (35%), Gaps = 35/151 (23%)
Query: 311 RPNEIEPPPPEM--PPWQKRQEGGGGRGGW--------GGGGG-----------GGGRGG 349
+P + + PP+M P + + G G G GGGGG G
Sbjct: 123 KPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPA 182
Query: 350 GGGGGGRGG--WGGGGGGWGGGGGGGGGWGGGGGGGRGGFQG---------RGDYGGRGG 398
GG GGR G + GG G G G G G
Sbjct: 183 SGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPG 242
Query: 399 YGGRGGYGGRGYGDPYGGGGGGGGGGGGGGG 429
Y G GG G G GGGGGG GGGGGGGG
Sbjct: 243 YSRPGAGGGGGGG---GGGGGGSGGGGGGGG 270
>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
[Homo sapiens]
Length = 2178
Score = 81.6 bits (200), Expect = 1e-15
Identities = 48/116 (41%), Positives = 52/116 (44%), Gaps = 15/116 (12%)
Query: 324 PWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGG 383
P R GGG GG GGGGGG G GGGGGG G GG G G GGGGGGG
Sbjct: 241 PGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGG-AGAGAVAAAAAAAAAAAGGGGGGG 299
Query: 384 RGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGG------GGGGGGGGGYRRY 433
G G GYG +G G G GGGG G GG++R+
Sbjct: 300 YG--------GSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRF 347
Score = 49.7 bits (117), Expect = 5e-06
Identities = 47/151 (31%), Positives = 54/151 (35%), Gaps = 35/151 (23%)
Query: 311 RPNEIEPPPPEM--PPWQKRQEGGGGRGGW--------GGGGG-----------GGGRGG 349
+P + + PP+M P + + G G G GGGGG G
Sbjct: 123 KPGDEDDAPPKMGEPAGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPA 182
Query: 350 GGGGGGRGG--WGGGGGGWGGGGGGGGGWGGGGGGGRGGFQG---------RGDYGGRGG 398
GG GGR G + GG G G G G G
Sbjct: 183 SGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMDPLQNSHEGYPNSQCNHYPG 242
Query: 399 YGGRGGYGGRGYGDPYGGGGGGGGGGGGGGG 429
Y G GG G G GGGGGG GGGGGGGG
Sbjct: 243 YSRPGAGGGGGGG---GGGGGGSGGGGGGGG 270
>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
Length = 1257
Score = 81.3 bits (199), Expect = 2e-15
Identities = 50/122 (40%), Positives = 57/122 (46%), Gaps = 15/122 (12%)
Query: 323 PPWQKRQEGGGG----RGGWGGGGG---GGGRGGGGGGGGRGGWGGG---GGGWGGGGGG 372
P ++ QEG GG WG G G GGG+G G G GG G G G GG
Sbjct: 474 PQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQ 533
Query: 373 GGGWGGGGGG-----GRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGG 427
G G GG G+G G G GG+ GG G GG+G GD +G GGG GGG G
Sbjct: 534 GSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKG 593
Query: 428 GG 429
G
Sbjct: 594 SG 595
Score = 67.4 bits (163), Expect = 2e-11
Identities = 46/108 (42%), Positives = 49/108 (45%), Gaps = 18/108 (16%)
Query: 332 GGGRGGWGGGG-------------GGGGRGG-GGGGGGRGG--WGGGGGGWGGGGGGGGG 375
GGG+G G G G G RGG G G G GG G G GG G GGG
Sbjct: 502 GGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGG 561
Query: 376 WGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGG 423
GGG G GG QG GD G G GG+ GG+G G G G G G
Sbjct: 562 QRPGGGHGSGGGQGPGD--GHGSGGGKNSGGGKGSGSGKGSDGDGERG 607
Score = 65.9 bits (159), Expect = 7e-11
Identities = 50/132 (37%), Positives = 53/132 (40%), Gaps = 28/132 (21%)
Query: 330 EGGGGRGGWGGGGGGGG-----RGGGGGGGGRGGWGGGGGGWGGGGGG----GGGWGGGG 380
EG G RGG G G G G R G G GG G GG G G G GG G G G GG
Sbjct: 525 EGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGG 584
Query: 381 GGGRGGFQGRGDYGGRGGYGGRG------GYGGR-------------GYGDPYGGGGGGG 421
G GG +G G G G G RG Y G+ P GG G
Sbjct: 585 GKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTG 644
Query: 422 GGGGGGGGYRRY 433
G G GG +R Y
Sbjct: 645 GKGKSGGRFRLY 656
Score = 62.8 bits (151), Expect = 6e-10
Identities = 52/164 (31%), Positives = 64/164 (39%), Gaps = 31/164 (18%)
Query: 290 REKTACAINKVLMGRVPDRGGRPNEIEPPPPEMPPWQKR---QEGGGGRGGWGGGGGGGG 346
R + A ++ R+ RP P E P R + G G G +G G G
Sbjct: 421 RSRRAVSVPASFFRRLAPSPARPRH----PAEAPNNGARLSSEVSGSGSGNFGEEGNPQG 476
Query: 347 RGGGGGGGG----RGGWGGGGGGWGGGGGGGGGWGGGG------GGGRGGFQGRGDYGGR 396
+ G GG WG G G G GGG G G G GG + +G+G GG+
Sbjct: 477 KEDQEGSGGDYMPMNNWGSGNGR---GSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQ 533
Query: 397 GGYG-----------GRGGYGGRGYGDPYGGGGGGGGGGGGGGG 429
G G G+G GG G G GGG G GGG G G
Sbjct: 534 GSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPG 577
>gi|15011916 nucleolar protein family A, member 1 [Homo sapiens]
Length = 217
Score = 80.9 bits (198), Expect = 2e-15
Identities = 37/51 (72%), Positives = 39/51 (76%)
Query: 323 PPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGG 373
PP +K GGGRGG GGG GGGGRGGG GGG RGG GGGGGG+ GG GGG
Sbjct: 161 PPGEKGPPRGGGRGGRGGGRGGGGRGGGRGGGFRGGRGGGGGGFRGGRGGG 211
Score = 75.1 bits (183), Expect = 1e-13
Identities = 42/73 (57%), Positives = 47/73 (64%), Gaps = 4/73 (5%)
Query: 319 PPEMPPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGG 378
P ++ P Q+ G G GGG GGRGGG GGGGRGG G GGG GG GGGGGG+ G
Sbjct: 148 PYKLLPLQRFLPRPPGEKGPPRGGGRGGRGGGRGGGGRGG-GRGGGFRGGRGGGGGGFRG 206
Query: 379 GGGGGRGGFQGRG 391
G G GGF+GRG
Sbjct: 207 GRG---GGFRGRG 216
Score = 70.1 bits (170), Expect = 4e-12
Identities = 38/61 (62%), Positives = 39/61 (63%), Gaps = 5/61 (8%)
Query: 339 GGGGGGGGRGGGGGGGGRGG----WGGGGGGWGGGGGGGGGWGG-GGGGGRGGFQGRGDY 393
GGG GG RGGGGGG RGG + GGGGG GGG GGG GG G GGGRGGF D
Sbjct: 5 GGGRGGFNRGGGGGGFNRGGSSNHFRGGGGGGGGGNFRGGGRGGFGRGGGRGGFNKGQDQ 64
Query: 394 G 394
G
Sbjct: 65 G 65
Score = 68.9 bits (167), Expect = 8e-12
Identities = 36/65 (55%), Positives = 40/65 (61%), Gaps = 6/65 (9%)
Query: 353 GGGRGGW--GGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGY 410
GGGRGG+ GGGGGG+ GG GGGGGGG G F+G GGRGG+G GG GG
Sbjct: 5 GGGRGGFNRGGGGGGFNRGGSSNHFRGGGGGGGGGNFRG----GGRGGFGRGGGRGGFNK 60
Query: 411 GDPYG 415
G G
Sbjct: 61 GQDQG 65
Score = 68.9 bits (167), Expect = 8e-12
Identities = 35/58 (60%), Positives = 38/58 (65%), Gaps = 4/58 (6%)
Query: 346 GRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRG 403
G G GGGRGG GGG GG G GGG GGG+ GG GGG GGF+G G GG+ GRG
Sbjct: 163 GEKGPPRGGGRGGRGGGRGGGGRGGGRGGGFRGGRGGGGGGFRG----GRGGGFRGRG 216
Score = 55.1 bits (131), Expect = 1e-07
Identities = 33/54 (61%), Positives = 34/54 (62%), Gaps = 10/54 (18%)
Query: 378 GGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGYR 431
GGG GGRGG GRG GGRGG G G GGR GGGGGG GG GGG+R
Sbjct: 170 GGGRGGRGG--GRGG-GGRGGGRGGGFRGGR-------GGGGGGFRGGRGGGFR 213
Score = 54.7 bits (130), Expect = 2e-07
Identities = 31/56 (55%), Positives = 34/56 (60%), Gaps = 4/56 (7%)
Query: 381 GGGRGGFQGRGDYGG--RGGYGG--RGGYGGRGYGDPYGGGGGGGGGGGGGGGYRR 432
GGGRGGF G GG RGG RGG GG G G+ GGG GG G GGG GG+ +
Sbjct: 5 GGGRGGFNRGGGGGGFNRGGSSNHFRGGGGGGGGGNFRGGGRGGFGRGGGRGGFNK 60
Score = 53.1 bits (126), Expect = 5e-07
Identities = 31/60 (51%), Positives = 32/60 (53%), Gaps = 13/60 (21%)
Query: 369 GGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGG 428
GGG GG GG GGGGRGG +G G GGRGG GG G GG GGG G G
Sbjct: 170 GGGRGGRGGGRGGGGRGGGRGGGFRGGRGGGGG-------------GFRGGRGGGFRGRG 216
Score = 49.3 bits (116), Expect = 7e-06
Identities = 27/46 (58%), Positives = 29/46 (63%), Gaps = 3/46 (6%)
Query: 386 GFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGYR 431
G +G GGRGG GG G GGRG G GGG GG GGGGGG+R
Sbjct: 163 GEKGPPRGGGRGGRGGGRGGGGRGGG---RGGGFRGGRGGGGGGFR 205
Score = 46.2 bits (108), Expect = 6e-05
Identities = 30/55 (54%), Positives = 31/55 (56%), Gaps = 9/55 (16%)
Query: 328 RQEGGGG--RGGW-----GGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGG 375
R GGGG RGG GGGGGGG GG GGGRGG+G GGG G G G
Sbjct: 13 RGGGGGGFNRGGSSNHFRGGGGGGG--GGNFRGGGRGGFGRGGGRGGFNKGQDQG 65
>gi|9506713 nucleolar protein family A, member 1 [Homo sapiens]
Length = 217
Score = 80.9 bits (198), Expect = 2e-15
Identities = 37/51 (72%), Positives = 39/51 (76%)
Query: 323 PPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGG 373
PP +K GGGRGG GGG GGGGRGGG GGG RGG GGGGGG+ GG GGG
Sbjct: 161 PPGEKGPPRGGGRGGRGGGRGGGGRGGGRGGGFRGGRGGGGGGFRGGRGGG 211
Score = 75.1 bits (183), Expect = 1e-13
Identities = 42/73 (57%), Positives = 47/73 (64%), Gaps = 4/73 (5%)
Query: 319 PPEMPPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGG 378
P ++ P Q+ G G GGG GGRGGG GGGGRGG G GGG GG GGGGGG+ G
Sbjct: 148 PYKLLPLQRFLPRPPGEKGPPRGGGRGGRGGGRGGGGRGG-GRGGGFRGGRGGGGGGFRG 206
Query: 379 GGGGGRGGFQGRG 391
G G GGF+GRG
Sbjct: 207 GRG---GGFRGRG 216
Score = 70.1 bits (170), Expect = 4e-12
Identities = 38/61 (62%), Positives = 39/61 (63%), Gaps = 5/61 (8%)
Query: 339 GGGGGGGGRGGGGGGGGRGG----WGGGGGGWGGGGGGGGGWGG-GGGGGRGGFQGRGDY 393
GGG GG RGGGGGG RGG + GGGGG GGG GGG GG G GGGRGGF D
Sbjct: 5 GGGRGGFNRGGGGGGFNRGGSSNHFRGGGGGGGGGNFRGGGRGGFGRGGGRGGFNKGQDQ 64
Query: 394 G 394
G
Sbjct: 65 G 65
Score = 68.9 bits (167), Expect = 8e-12
Identities = 36/65 (55%), Positives = 40/65 (61%), Gaps = 6/65 (9%)
Query: 353 GGGRGGW--GGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGY 410
GGGRGG+ GGGGGG+ GG GGGGGGG G F+G GGRGG+G GG GG
Sbjct: 5 GGGRGGFNRGGGGGGFNRGGSSNHFRGGGGGGGGGNFRG----GGRGGFGRGGGRGGFNK 60
Query: 411 GDPYG 415
G G
Sbjct: 61 GQDQG 65
Score = 68.9 bits (167), Expect = 8e-12
Identities = 35/58 (60%), Positives = 38/58 (65%), Gaps = 4/58 (6%)
Query: 346 GRGGGGGGGGRGGWGGGGGGWGGGGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRG 403
G G GGGRGG GGG GG G GGG GGG+ GG GGG GGF+G G GG+ GRG
Sbjct: 163 GEKGPPRGGGRGGRGGGRGGGGRGGGRGGGFRGGRGGGGGGFRG----GRGGGFRGRG 216
Score = 55.1 bits (131), Expect = 1e-07
Identities = 33/54 (61%), Positives = 34/54 (62%), Gaps = 10/54 (18%)
Query: 378 GGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGYR 431
GGG GGRGG GRG GGRGG G G GGR GGGGGG GG GGG+R
Sbjct: 170 GGGRGGRGG--GRGG-GGRGGGRGGGFRGGR-------GGGGGGFRGGRGGGFR 213
Score = 54.7 bits (130), Expect = 2e-07
Identities = 31/56 (55%), Positives = 34/56 (60%), Gaps = 4/56 (7%)
Query: 381 GGGRGGFQGRGDYGG--RGGYGG--RGGYGGRGYGDPYGGGGGGGGGGGGGGGYRR 432
GGGRGGF G GG RGG RGG GG G G+ GGG GG G GGG GG+ +
Sbjct: 5 GGGRGGFNRGGGGGGFNRGGSSNHFRGGGGGGGGGNFRGGGRGGFGRGGGRGGFNK 60
Score = 53.1 bits (126), Expect = 5e-07
Identities = 31/60 (51%), Positives = 32/60 (53%), Gaps = 13/60 (21%)
Query: 369 GGGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGG 428
GGG GG GG GGGGRGG +G G GGRGG GG G GG GGG G G
Sbjct: 170 GGGRGGRGGGRGGGGRGGGRGGGFRGGRGGGGG-------------GFRGGRGGGFRGRG 216
Score = 49.3 bits (116), Expect = 7e-06
Identities = 27/46 (58%), Positives = 29/46 (63%), Gaps = 3/46 (6%)
Query: 386 GFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGYR 431
G +G GGRGG GG G GGRG G GGG GG GGGGGG+R
Sbjct: 163 GEKGPPRGGGRGGRGGGRGGGGRGGG---RGGGFRGGRGGGGGGFR 205
Score = 46.2 bits (108), Expect = 6e-05
Identities = 30/55 (54%), Positives = 31/55 (56%), Gaps = 9/55 (16%)
Query: 328 RQEGGGG--RGGW-----GGGGGGGGRGGGGGGGGRGGWGGGGGGWGGGGGGGGG 375
R GGGG RGG GGGGGGG GG GGGRGG+G GGG G G G
Sbjct: 13 RGGGGGGFNRGGSSNHFRGGGGGGG--GGNFRGGGRGGFGRGGGRGGFNKGQDQG 65
>gi|7710145 methyl-CpG binding domain protein 2 testis-specific
isoform [Homo sapiens]
Length = 302
Score = 75.5 bits (184), Expect = 9e-14
Identities = 52/119 (43%), Positives = 56/119 (47%), Gaps = 20/119 (16%)
Query: 327 KRQEGGGGRGGWGGGGGGGGRGGGGGG-------------GGRGGWGGGGGGWGGGGGGG 373
+++EG GG G GG GG G G RGG G G G W G GG
Sbjct: 13 EQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGG-GRGRGRWKQAGRGG 71
Query: 374 GGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGYRR 432
G G G G GRG +GRG GRG R GG G G GGG GGGG GGGG RR
Sbjct: 72 GVCGRGRGRGRGRGRGRGRGRGRG----RPPSGGSGLGGD--GGGCGGGGSGGGGAPRR 124
Score = 65.1 bits (157), Expect = 1e-10
Identities = 44/111 (39%), Positives = 51/111 (45%), Gaps = 10/111 (9%)
Query: 307 DRGGRPNEIEPPPPEMPPWQKRQEGGGGRGGWGGGGGGGGRGGGGGGGGRGGWGGGGGGW 366
++GG+ + + P P + + GG GRG W G GGG G G G GRG G G G
Sbjct: 33 EQGGQGSALAPSPVSGVRREGARGGGRGRGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGR 92
Query: 367 GGG---------GGGGGGWGGGGGGGRGGFQGRGDYGGRGGYGGRGGYGGR 408
G G GG GGG GGGG GG GG R G G G G R
Sbjct: 93 GRGRPPSGGSGLGGDGGGCGGGGSGG-GGAPRREPVPFPSGSAGPGPRGPR 142
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.140 0.431
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,132,382
Number of Sequences: 37866
Number of extensions: 1489564
Number of successful extensions: 79941
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 971
Number of HSP's successfully gapped in prelim test: 277
Number of HSP's that attempted gapping in prelim test: 16737
Number of HSP's gapped (non-prelim): 24504
length of query: 433
length of database: 18,247,518
effective HSP length: 105
effective length of query: 328
effective length of database: 14,271,588
effective search space: 4681080864
effective search space used: 4681080864
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.