Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help
Name: IRS4 Sequence: fasta or formatted (1257aa) NCBI GI: 4504733
Description:

insulin receptor substrate 4

Referenced in:

Pancreas and Insulin

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            11.5        144          10
 C cysteine            1.4         18           2
 D aspartate           5.3         66           3
 E glutamate           6.0         76           3
 F phenylalanine       3.5         44           2
 G glycine            10.8        136           3
 H histidine           1.8         23           1
 I isoleucine          2.1         26           2
 K lysine              3.8         48           2
 L leucine             6.1         77           3
 M methionine          1.9         24           3
 N asparagine          3.4         43           2
 P proline             9.1        115          12
 Q glutamine           3.6         45           3
 R arginine            8.4        105           3
 S serine             10.7        135           3
 T threonine           2.9         36           2
 V valine              4.5         57           3
 W tryptophan          0.9         11           1
 Y tyrosine            2.2         28           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   insulin receptor substrate 4 
IRS1                  0.115   insulin receptor substrate 1 
IRS2                  0.108   insulin receptor substrate 2 
KRT9                  0.033   keratin 9 
KRT2                  0.027   keratin 2 
FLG2                  0.027   filaggrin family member 2 
LOR                   0.026   loricrin 
KRT1                  0.026   keratin 1 
HRNR                  0.025   hornerin 
KRT10                 0.025   keratin 10 
FUS                   0.024   fusion (involved in t(12;16) in malignant liposarcoma...
HNRNPA3               0.024   heterogeneous nuclear ribonucleoprotein A3 
FAM98B                0.022   family with sequence similarity 98, member B isofor...
COL1A1                0.022   alpha 1 type I collagen preproprotein 
DMKN                  0.021   dermokine isoform 2 precursor 
COL3A1                0.021   collagen type III alpha 1 preproprotein 
TAF15                 0.021   TBP-associated factor 15 isoform 2 
TAF15                 0.021   TBP-associated factor 15 isoform 1 
DMKN                  0.021   dermokine isoform 4 precursor 
DMKN                  0.021   dermokine isoform 5 precursor 
DMKN                  0.021   dermokine isoform 3 precursor 
HNRNPA1               0.021   heterogeneous nuclear ribonucleoprotein A1 isoform b...
HNRNPUL1              0.020   heterogeneous nuclear ribonucleoprotein U-like 1 iso...
HNRNPUL1              0.020   heterogeneous nuclear ribonucleoprotein U-like 1 iso...
PPP1R10               0.019   protein phosphatase 1, regulatory subunit 10 
RPGR                  0.019   retinitis pigmentosa GTPase regulator isoform C [Hom...
COL5A2                0.019   alpha 2 type V collagen preproprotein 
HNRNPA2B1             0.019   heterogeneous nuclear ribonucleoprotein A2/B1 isofor...
HNRNPA2B1             0.019   heterogeneous nuclear ribonucleoprotein A2/B1 isoform...
COL2A1                0.019   collagen, type II, alpha 1 isoform 1 precursor [Hom...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press