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Search of human proteins with 14211943
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|14211943 lysyl oxidase-like 3 precursor [Homo sapiens]
(753 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|14211943 lysyl oxidase-like 3 precursor [Homo sapiens] 1611 0.0
gi|4505011 lysyl oxidase-like 2 precursor [Homo sapiens] 907 0.0
gi|67782349 lysyl oxidase-like 4 precursor [Homo sapiens] 870 0.0
gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens] 264 2e-70
gi|148539844 deleted in malignant brain tumors 1 isoform c precu... 264 2e-70
gi|148539842 deleted in malignant brain tumors 1 isoform b precu... 264 2e-70
gi|148539840 deleted in malignant brain tumors 1 isoform a precu... 264 2e-70
gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens] 261 2e-69
gi|20149540 lysyl oxidase preproprotein [Homo sapiens] 226 6e-59
gi|50659091 scavenger receptor cysteine-rich type 1 precursor [H... 226 8e-59
gi|18152779 scavenger receptor cysteine rich domain containing, ... 224 3e-58
gi|67782346 lysyl oxidase-like 1 preproprotein [Homo sapiens] 222 1e-57
gi|44889963 CD163 antigen isoform b [Homo sapiens] 212 1e-54
gi|44662834 CD163 antigen isoform a [Homo sapiens] 212 1e-54
gi|4506143 neurotrypsin precursor [Homo sapiens] 211 3e-54
gi|222352122 hypothetical protein LOC284297 [Homo sapiens] 196 7e-50
gi|5174411 CD5 molecule-like [Homo sapiens] 169 1e-41
gi|239752563 PREDICTED: hypothetical protein [Homo sapiens] 160 5e-39
gi|194018748 CD6 molecule [Homo sapiens] 135 1e-31
gi|20357512 macrophage scavenger receptor 1 isoform type 1 [Homo... 109 8e-24
gi|5803080 macrophage receptor with collagenous structure [Homo ... 101 3e-21
gi|5031863 galectin 3 binding protein [Homo sapiens] 100 4e-21
gi|47271477 scavenger receptor class A, member 5 [Homo sapiens] 100 8e-21
gi|187936955 HHIP-like protein 1 isoform a [Homo sapiens] 100 8e-21
gi|20357515 macrophage scavenger receptor 1 isoform type 3 [Homo... 55 3e-07
gi|166197668 CD5 molecule [Homo sapiens] 44 4e-04
gi|119392081 complement factor I preproprotein [Homo sapiens] 40 0.008
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap... 36 0.12
gi|14602457 transmembrane protease, serine 3 isoform 3 [Homo sap... 36 0.12
gi|239752583 PREDICTED: hypothetical protein XP_002348171 [Homo ... 35 0.34
>gi|14211943 lysyl oxidase-like 3 precursor [Homo sapiens]
Length = 753
Score = 1611 bits (4172), Expect = 0.0
Identities = 753/753 (100%), Positives = 753/753 (100%)
Query: 1 MRPVSVWQWSPWGLLLCLLCSSCLGSPSPSTGPEKKAGSQGLRFRLAGFPRKPYEGRVEI 60
MRPVSVWQWSPWGLLLCLLCSSCLGSPSPSTGPEKKAGSQGLRFRLAGFPRKPYEGRVEI
Sbjct: 1 MRPVSVWQWSPWGLLLCLLCSSCLGSPSPSTGPEKKAGSQGLRFRLAGFPRKPYEGRVEI 60
Query: 61 QRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQS 120
QRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQS
Sbjct: 61 QRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQS 120
Query: 121 VTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAVGWGRR 180
VTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAVGWGRR
Sbjct: 121 VTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAVGWGRR 180
Query: 181 PLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHS 240
PLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHS
Sbjct: 181 PLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHS 240
Query: 241 FGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSK 300
FGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSK
Sbjct: 241 FGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSK 300
Query: 301 PQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGA 360
PQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGA
Sbjct: 301 PQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGA 360
Query: 361 RMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLS 420
RMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLS
Sbjct: 361 RMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLS 420
Query: 421 GGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSG 480
GGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSG
Sbjct: 421 GGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSG 480
Query: 481 NITEVVMSGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAGVICSETASDLLLHSALVQE 540
NITEVVMSGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAGVICSETASDLLLHSALVQE
Sbjct: 481 NITEVVMSGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAGVICSETASDLLLHSALVQE 540
Query: 541 TAYIEDRPLHMLYCAAEENCLASSARSANWPYGHRRLLRFSSQIHNLGRADFRPKAGRHS 600
TAYIEDRPLHMLYCAAEENCLASSARSANWPYGHRRLLRFSSQIHNLGRADFRPKAGRHS
Sbjct: 541 TAYIEDRPLHMLYCAAEENCLASSARSANWPYGHRRLLRFSSQIHNLGRADFRPKAGRHS 600
Query: 601 WVWHECHGHYHSMDIFTHYDILTPNGTKVAEGHKASFCLEDTECQEDVSKRYECANFGEQ 660
WVWHECHGHYHSMDIFTHYDILTPNGTKVAEGHKASFCLEDTECQEDVSKRYECANFGEQ
Sbjct: 601 WVWHECHGHYHSMDIFTHYDILTPNGTKVAEGHKASFCLEDTECQEDVSKRYECANFGEQ 660
Query: 661 GITVGCWDLYRHDIDCQWIDITDVKPGNYILQVVINPNFEVAESDFTNNAMKCNCKYDGH 720
GITVGCWDLYRHDIDCQWIDITDVKPGNYILQVVINPNFEVAESDFTNNAMKCNCKYDGH
Sbjct: 661 GITVGCWDLYRHDIDCQWIDITDVKPGNYILQVVINPNFEVAESDFTNNAMKCNCKYDGH 720
Query: 721 RIWVHNCHIGDAFSEEANRRFERYPGQTSNQII 753
RIWVHNCHIGDAFSEEANRRFERYPGQTSNQII
Sbjct: 721 RIWVHNCHIGDAFSEEANRRFERYPGQTSNQII 753
>gi|4505011 lysyl oxidase-like 2 precursor [Homo sapiens]
Length = 774
Score = 907 bits (2344), Expect = 0.0
Identities = 413/727 (56%), Positives = 539/727 (74%), Gaps = 9/727 (1%)
Query: 33 PEKKAGSQGLRFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEAT 92
P+ A ++ RLAG RK EGRVE+ G+WGT+CDDDF++ AAH++CRELG+ EA
Sbjct: 47 PQAPANVAKIQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAK 106
Query: 93 GWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGF 152
WT S+ YG G G IWLDNL C+G E ++ C S GWG +DC H ED GV+C D+R+PGF
Sbjct: 107 SWTASSSYGKGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGF 166
Query: 153 SDSNVI--EVEH-HLQVEEVRIRPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHN 209
N + ++E+ ++QVE++RIR + R+ PV EG VEV+ W Q+CDK W+A N
Sbjct: 167 KFDNSLINQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKN 226
Query: 210 SHVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTA 269
S VVCGM GFP E+ N Y++ A R++ + + C GTEAH+S C L + D
Sbjct: 227 SRVVCGMFGFPGERTYNTKVYKMFASRRKQRYWPFSMDCTGTEAHISSCKLGPQVSLDPM 286
Query: 270 R---CPGGGPAVVSCVPGPVYAASSGQKKQQQSKPQGEARVRLKGGAHPGEGRVEVLKAS 326
+ C G PAVVSCVPG V++ + ++ KP+ + VRL+GGA+ GEGRVEVLK
Sbjct: 287 KNVTCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPE-QPLVRLRGGAYIGEGRVEVLKNG 345
Query: 327 TWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKC 386
WGTVCD KWDL +ASVVCRELGFGSA+EA++G+R+GQG+G IHL+E++C+G E S+ C
Sbjct: 346 EWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHLNEIQCTGNEKSIIDC 405
Query: 387 PHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLIC 446
N ++ C+H +DAGVRCN P G + ++RL+GGR+ +EGRVEV + G L WG++C
Sbjct: 406 KF-NAESQGCNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVEVLVERNGSLVWGMVC 464
Query: 447 GDDWGTLEAMVACRQLGLGYANHGLQETWYWDSG-NITEVVMSGVRCTGTELSLDQCAHH 505
G +WG +EAMV CRQLGLG+A++ QETWYW N +VVMSGV+C+GTELSL C H
Sbjct: 465 GQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGVKCSGTELSLAHCRHD 524
Query: 506 GTHITCKRTGTRFTAGVICSETASDLLLHSALVQETAYIEDRPLHMLYCAAEENCLASSA 565
G + C + G ++ AGV CSETA DL+L++ +VQ+T Y+EDRP+ ML CA EENCL++SA
Sbjct: 525 GEDVACPQGGVQYGAGVACSETAPDLVLNAEMVQQTTYLEDRPMFMLQCAMEENCLSASA 584
Query: 566 RSANWPYGHRRLLRFSSQIHNLGRADFRPKAGRHSWVWHECHGHYHSMDIFTHYDILTPN 625
+ G+RRLLRFSSQIHN G++DFRPK GRH+W+WH+CH HYHSM++FTHYD+L N
Sbjct: 585 AQTDPTTGYRRLLRFSSQIHNNGQSDFRPKNGRHAWIWHDCHRHYHSMEVFTHYDLLNLN 644
Query: 626 GTKVAEGHKASFCLEDTECQEDVSKRYECANFGEQGITVGCWDLYRHDIDCQWIDITDVK 685
GTKVAEGHKASFCLEDTEC+ D+ K YECANFG+QGIT+GCWD+YRHDIDCQW+DITDV
Sbjct: 645 GTKVAEGHKASFCLEDTECEGDIQKNYECANFGDQGITMGCWDMYRHDIDCQWVDITDVP 704
Query: 686 PGNYILQVVINPNFEVAESDFTNNAMKCNCKYDGHRIWVHNCHIGDAFSEEANRRFERYP 745
PG+Y+ QVVINPNFEVAESD++NN MKC +YDGHRIW++NCHIG +FSEE ++FE +
Sbjct: 705 PGDYLFQVVINPNFEVAESDYSNNIMKCRSRYDGHRIWMYNCHIGGSFSEETEKKFEHFS 764
Query: 746 GQTSNQI 752
G +NQ+
Sbjct: 765 GLLNNQL 771
>gi|67782349 lysyl oxidase-like 4 precursor [Homo sapiens]
Length = 756
Score = 870 bits (2248), Expect = 0.0
Identities = 418/762 (54%), Positives = 523/762 (68%), Gaps = 26/762 (3%)
Query: 9 WSPWGLLLCLLCSSCLGSPSPSTGPEKKAGSQGLRFRLAGFPRKPYEGRVEIQRAGEWGT 68
WSP L L LG P PS P+ + + RL G KP EGR+E+ G+WGT
Sbjct: 3 WSPPATLFLFLL--LLGQPPPSR-PQSLGTT---KLRLVGPESKPEEGRLEVLHQGQWGT 56
Query: 69 ICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRG 128
+CDD+F +Q A + CR+LGF A W HSAKYG G G IWLDN+ C GTE S+ +C S G
Sbjct: 57 VCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNG 116
Query: 129 WGNSDCTHDEDAGVICKDQRLPGFSDSNVIEV--EHHLQVEEVRIRPAVGWGRRPLPVTE 186
WG SDC+H ED GVIC +R G+ V ++EEVR++P + ++ PVTE
Sbjct: 117 WGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTE 176
Query: 187 GLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYR-------------LL 233
G VEV+ W QVCD+GW+ +NS VVCGMLGFPSE V++ +YR L
Sbjct: 177 GAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLK 236
Query: 234 AQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTAR--CPGGGPAVVSCVPGPVYAASS 291
+ ++SF +H V C+GTE H++ C ++ A R CPGG AVVSCV GP +
Sbjct: 237 SLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPK 296
Query: 292 GQKKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFG 351
K Q++ E RVRL+ GA GEGRVEVL WGTVCD +W+L +ASVVCR+LGFG
Sbjct: 297 -TKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFG 355
Query: 352 SAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYT 411
SAREAL GAR+GQG+G IHLSEVRC G E +L CP + C H DA VRCN+P
Sbjct: 356 SAREALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNM 415
Query: 412 GAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGL 471
G + ++RL+GGR EG +EVQ+ G RWG +C ++WG EAMVACRQLGLG+A H
Sbjct: 416 GFQNQVRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAY 475
Query: 472 QETWYWD-SGNITEVVMSGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAGVICSETASD 530
+ETW+W + EVVMSGVRC+GTEL+L QC HG + C G RF AGV C ++A D
Sbjct: 476 KETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGP-VHCSHGGGRFLAGVSCMDSAPD 534
Query: 531 LLLHSALVQETAYIEDRPLHMLYCAAEENCLASSARSANWPYGHRRLLRFSSQIHNLGRA 590
L++++ LVQETAY+EDRPL LYCA EENCL+ SA +WPYG+RRLLRFS+QI+NLGR
Sbjct: 535 LVMNAQLVQETAYLEDRPLSQLYCAHEENCLSKSADHMDWPYGYRRLLRFSTQIYNLGRT 594
Query: 591 DFRPKAGRHSWVWHECHGHYHSMDIFTHYDILTPNGTKVAEGHKASFCLEDTECQEDVSK 650
DFRPK GR SWVWH+CH HYHS+++FTHYD+LT NG+KVAEGHKASFCLEDT C + +
Sbjct: 595 DFRPKTGRDSWVWHQCHRHYHSIEVFTHYDLLTLNGSKVAEGHKASFCLEDTNCPTGLQR 654
Query: 651 RYECANFGEQGITVGCWDLYRHDIDCQWIDITDVKPGNYILQVVINPNFEVAESDFTNNA 710
RY CANFGEQG+TVGCWD YRHDIDCQW+DITDV PGNYI QV++NP++EVAESDF+NN
Sbjct: 655 RYACANFGEQGVTVGCWDTYRHDIDCQWVDITDVGPGNYIFQVIVNPHYEVAESDFSNNM 714
Query: 711 MKCNCKYDGHRIWVHNCHIGDAFSEEANRRFERYPGQTSNQI 752
++C CKYDGHR+W+HNCH G+++ A E+ +N I
Sbjct: 715 LQCRCKYDGHRVWLHNCHTGNSYPANAELSLEQEQRLRNNLI 756
>gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens]
Length = 1662
Score = 264 bits (675), Expect = 2e-70
Identities = 192/549 (34%), Positives = 249/549 (45%), Gaps = 72/549 (13%)
Query: 26 SPSPSTGPEKKAGSQGLRFRLA-----GFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAH 80
+PSP T P A + G LA G R +GRVE+ G WGT+CDD + A+
Sbjct: 341 TPSPDTWPTSHASTAGSESSLALRLVNGGDR--CQGRVEVLYRGSWGTVCDDSWDTSDAN 398
Query: 81 ILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDA 140
++CR+LG AT +A++G G+G I LD++ CSG E + C GW + +C H EDA
Sbjct: 399 VVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDA 458
Query: 141 GVICKDQRL-----PGFSDSNVIEVEHHLQVEEVRIRPA-----VGWGRRPLPVTEGLVE 190
GVIC PG D L V + V G R +G VE
Sbjct: 459 GVICSAAHSWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDR----CQGRVE 514
Query: 191 VRLPDGWSQVCDKGWSAHNSHVVCGMLG--FPSEKRVNAAFYRLLAQRQQHSFGLHGVAC 248
V W VCD W ++++VVC LG + NA F + L V C
Sbjct: 515 VLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARF-----GQGSGPIVLDDVRC 569
Query: 249 VGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKPQGEAR-- 306
G E++L C + +++ C A V C AA S + + P A
Sbjct: 570 SGNESYLWSCPHNGWLSHN---CGHSEDAGVICS-----AAQSRSTPRPDTWPTSHASTA 621
Query: 307 -------VRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSG 359
+RL G +GRVEVL +WGTVCD WD + A+VVCR+LG G A A
Sbjct: 622 GSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGN 681
Query: 360 ARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNL----------- 408
AR GQG G I L +VRCSG E LW CPH + +C HS+DAGV C+
Sbjct: 682 ARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDT 741
Query: 409 -PYTGAET-------RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACR 460
P + A T +RL G + GRVEV G WG +C D W T +A V CR
Sbjct: 742 WPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQG----SWGTVCDDYWDTNDANVVCR 797
Query: 461 QLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHGTHITCKRTGTRFTA 520
QLG G+A + +V+ VRC+G E L C H+G G A
Sbjct: 798 QLGCGWAMSAPGNAQFGQGSG--PIVLDDVRCSGHESYLWSCPHNGW--LSHNCGHHEDA 853
Query: 521 GVICSETAS 529
GVICS S
Sbjct: 854 GVICSAAQS 862
Score = 257 bits (657), Expect = 2e-68
Identities = 182/553 (32%), Positives = 249/553 (45%), Gaps = 64/553 (11%)
Query: 18 LLCSSCLGSPSPSTG-------------PEKKAGSQG-LRFRLAGFPRKPYEGRVEIQRA 63
++CS+ +PS G P GS+ L RL + +GRVE+
Sbjct: 460 VICSAAHSWSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDR-CQGRVEVLYR 518
Query: 64 GEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTE 123
G WGT+CDD + A+++CR+LG A +A++G G+G I LD++ CSG E +
Sbjct: 519 GSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWS 578
Query: 124 CASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQV---EEVRIRPAVGWGRR 180
C GW + +C H EDAGVIC + + H + +R G R
Sbjct: 579 CPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDR- 637
Query: 181 PLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLG--FPSEKRVNAAFYRLLAQRQQ 238
+G VEV W VCD W ++++VVC LG + NA F +
Sbjct: 638 ----CQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARF-----GQGS 688
Query: 239 HSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQ 298
L V C G E++L C + +++ G + P + + +
Sbjct: 689 GPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSRAS 748
Query: 299 SK-PQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREAL 357
+ + +RL G GRVEVL +WGTVCD WD + A+VVCR+LG G A A
Sbjct: 749 TAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAP 808
Query: 358 SGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRC----------- 406
A+ GQG G I L +VRCSG E LW CPH + +C H +DAGV C
Sbjct: 809 GNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRP 868
Query: 407 ------NLPY--TGAETRI--RLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAM 456
NLP G+E+ + RL G + GRVEV G WG +C D W T +A
Sbjct: 869 DTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGS----WGTVCDDSWDTNDAN 924
Query: 457 VACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHG--THITCKRT 514
V CRQLG G+A + +V+ VRC+G E L C H G TH
Sbjct: 925 VVCRQLGCGWAMSAPGNARFGQGSG--PIVLDDVRCSGNESYLWSCPHKGWLTH----NC 978
Query: 515 GTRFTAGVICSET 527
G AGVICS T
Sbjct: 979 GHHEDAGVICSAT 991
Score = 251 bits (642), Expect = 1e-66
Identities = 185/565 (32%), Positives = 253/565 (44%), Gaps = 59/565 (10%)
Query: 5 SVWQWSPWGLLLCLLCSSCLGS--PSPST--GPEKKAGSQGLRFRLAGFPRKPYEGRVEI 60
+V + SP L L + GS PS ST + GL RL + +GRVEI
Sbjct: 59 TVAEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGR-CQGRVEI 117
Query: 61 QRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQS 120
G WGT+CDD + A+++CR+LG A +A +G G+G I LD++ CSG E
Sbjct: 118 LYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESY 177
Query: 121 VTECASRGWGNSDCTHDEDAGVICKDQRLPGF--SDSNVIEVEHHLQVE----EVRIRPA 174
+ C GW + +C H EDAGVIC + +S + + + E + +R
Sbjct: 178 LWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLV 237
Query: 175 VGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLG--FPSEKRVNAAFYRL 232
G R G VEV W VCD W ++++VVC LG + NA F
Sbjct: 238 NGGDR-----CRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQF--- 289
Query: 233 LAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSG 292
+ L V C G E++L C + ++ G + P + +
Sbjct: 290 --GQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTW 347
Query: 293 QKKQQQSK-PQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFG 351
+ + +RL G +GRVEVL +WGTVCD WD A+VVCR+LG G
Sbjct: 348 PTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCG 407
Query: 352 SAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYT 411
A A AR GQG G I L +VRCSG E LW CPH + +C HS+DAGV C+ ++
Sbjct: 408 WATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHS 467
Query: 412 -------------------------GAET--RIRLSGGRSQHEGRVEVQIGGPGPLRWGL 444
G+E+ +RL G + +GRVEV G WG
Sbjct: 468 WSTPSPGERDRTDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRG----SWGT 523
Query: 445 ICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAH 504
+C D W T +A V CRQLG G+A + +V+ VRC+G E L C H
Sbjct: 524 VCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSG--PIVLDDVRCSGNESYLWSCPH 581
Query: 505 HGTHITCKRTGTRFTAGVICSETAS 529
+G G AGVICS S
Sbjct: 582 NGW--LSHNCGHSEDAGVICSAAQS 604
Score = 208 bits (530), Expect = 1e-53
Identities = 142/415 (34%), Positives = 190/415 (45%), Gaps = 31/415 (7%)
Query: 18 LLCSSCLG--SPSPSTGPEKKAGSQGLRFRLA-----GFPRKPYEGRVEIQRAGEWGTIC 70
++CS+ +P P T P A + G LA G R +GRVE+ G WGT+C
Sbjct: 597 VICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDR--CQGRVEVLYQGSWGTVC 654
Query: 71 DDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWG 130
DD + A+++CR+LG A +A++G G+G I LD++ CSG E + C GW
Sbjct: 655 DDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWL 714
Query: 131 NSDCTHDEDAGVICK--DQRLPGFSDSNVIEVEHHLQVEEVRIRPAVGWGRRPLPVTEGL 188
+ +C H EDAGVIC R D+ E V G R G
Sbjct: 715 SHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDR----CRGR 770
Query: 189 VEVRLPDGWSQVCDKGWSAHNSHVVCGMLG--FPSEKRVNAAFYRLLAQRQQHSFGLHGV 246
VEV W VCD W ++++VVC LG + NA F + L V
Sbjct: 771 VEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQF-----GQGSGPIVLDDV 825
Query: 247 ACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKP----- 301
C G E++L C + +++ C A V C + + P
Sbjct: 826 RCSGHESYLWSCPHNGWLSHN---CGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVG 882
Query: 302 -QGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGA 360
+ +RL G GRVEVL +WGTVCD WD + A+VVCR+LG G A A A
Sbjct: 883 SESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNA 942
Query: 361 RMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAET 415
R GQG G I L +VRCSG E LW CPHK +C H +DAGV C+ + T
Sbjct: 943 RFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTT 997
Score = 107 bits (266), Expect = 5e-23
Identities = 46/94 (48%), Positives = 63/94 (67%)
Query: 56 GRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCS 115
GRVEI G WGT+CDD +T+Q A ++CR+LG A +A +G G+G I LD++ CS
Sbjct: 1146 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1205
Query: 116 GTEQSVTECASRGWGNSDCTHDEDAGVICKDQRL 149
GTE ++ +C +RGW + +C H EDAGVIC L
Sbjct: 1206 GTESTLWQCRNRGWFSHNCNHREDAGVICSGNHL 1239
Score = 99.8 bits (247), Expect = 8e-21
Identities = 44/90 (48%), Positives = 57/90 (63%)
Query: 318 GRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCS 377
GRVE+ TWGTVCD W + A VVCR+LG G A AL A G G G I L +V CS
Sbjct: 1146 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1205
Query: 378 GQELSLWKCPHKNITAEDCSHSQDAGVRCN 407
G E +LW+C ++ + +C+H +DAGV C+
Sbjct: 1206 GTESTLWQCRNRGWFSHNCNHREDAGVICS 1235
Score = 63.9 bits (154), Expect = 5e-10
Identities = 41/98 (41%), Positives = 50/98 (51%), Gaps = 8/98 (8%)
Query: 428 GRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVM 487
GRVE+ GG WG +C D W EA V CRQLG G A L Y+ SG+ + +
Sbjct: 1146 GRVEIYHGGT----WGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNA-YFGSGS-GPITL 1199
Query: 488 SGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAGVICS 525
V C+GTE +L QC + G R AGVICS
Sbjct: 1200 DDVECSGTESTLWQCRNRGWF--SHNCNHREDAGVICS 1235
Score = 34.7 bits (78), Expect = 0.34
Identities = 23/72 (31%), Positives = 28/72 (38%), Gaps = 3/72 (4%)
Query: 187 GLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFGLHGV 246
G VE+ W VCD W+ + VVC LG R +A L V
Sbjct: 1146 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGC---GRAVSALGNAYFGSGSGPITLDDV 1202
Query: 247 ACVGTEAHLSLC 258
C GTE+ L C
Sbjct: 1203 ECSGTESTLWQC 1214
>gi|148539844 deleted in malignant brain tumors 1 isoform c precursor
[Homo sapiens]
Length = 2403
Score = 264 bits (675), Expect = 2e-70
Identities = 180/536 (33%), Positives = 245/536 (45%), Gaps = 52/536 (9%)
Query: 26 SPSPSTGPEKKAGSQGLRFRLA-----GFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAH 80
+PSP T P A + G LA G R +GRVE+ G WGT+CDD + A+
Sbjct: 830 TPSPDTWPTSHASTAGPESSLALRLVNGGDR--CQGRVEVLYRGSWGTVCDDSWDTSDAN 887
Query: 81 ILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDA 140
++CR+LG AT +A++G G+G I LD++ CSG E + C GW + +C H EDA
Sbjct: 888 VVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDA 947
Query: 141 GVICKDQRL-----PGFSDSNVIEVEHHLQVEEVRIRPAVGWGRRPLPVTEGLVEVRLPD 195
GVIC P + + + +R G R +G VEV
Sbjct: 948 GVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDR-----CQGRVEVLYQG 1002
Query: 196 GWSQVCDKGWSAHNSHVVCGMLG--FPSEKRVNAAFYRLLAQRQQHSFGLHGVACVGTEA 253
W VCD W ++++VVC LG + NA F + L V C G E+
Sbjct: 1003 SWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARF-----GQGSGPIVLDDVRCSGHES 1057
Query: 254 HLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSK-PQGEARVRLKGG 312
+L C + +++ G + P + + + + +RL G
Sbjct: 1058 YLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNG 1117
Query: 313 AHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLS 372
+GRVEVL +WGTVCD WD + A+VVCR+LG G A A AR GQG G I L
Sbjct: 1118 GDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLD 1177
Query: 373 EVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNL------------PYTGAET----- 415
+VRCSG E LW CPH + +C H +DAGV C+ P + A T
Sbjct: 1178 DVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSES 1237
Query: 416 --RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQE 473
+RL G + +GRVEV G WG +C D W T +A V CRQLG G+A
Sbjct: 1238 SLALRLVNGGDRCQGRVEVLYRG----SWGTVCDDYWDTNDANVVCRQLGCGWATSAPGN 1293
Query: 474 TWYWDSGNITEVVMSGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAGVICSETAS 529
+ +V+ VRC+G E L C H+G G AGVICS + S
Sbjct: 1294 ARFGQGSG--PIVLDDVRCSGHESYLWSCPHNGW--LSHNCGHHEDAGVICSASQS 1345
Score = 264 bits (675), Expect = 2e-70
Identities = 185/546 (33%), Positives = 252/546 (46%), Gaps = 58/546 (10%)
Query: 18 LLCSSCLGSPSPS--TGPEKKAGSQGLRFRLA-----GFPRKPYEGRVEIQRAGEWGTIC 70
++CS+ P+PS T P A + G LA G R +GRVE+ G WGT+C
Sbjct: 1209 VICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDR--CQGRVEVLYRGSWGTVC 1266
Query: 71 DDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWG 130
DD + A+++CR+LG AT +A++G G+G I LD++ CSG E + C GW
Sbjct: 1267 DDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWL 1326
Query: 131 NSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQV---EEVRIRPAVGWGRRPLPVTEG 187
+ +C H EDAGVIC + + H + +R G R +G
Sbjct: 1327 SHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDR-----CQG 1381
Query: 188 LVEVRLPDGWSQVCDKGWSAHNSHVVCGML--GFPSEKRVNAAFYRLLAQRQQHSFGLHG 245
VEV W VCD W ++++VVC L G+ + NA F + L
Sbjct: 1382 RVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARF-----GQGSGPIVLDD 1436
Query: 246 VACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASS-GQKKQQQSKPQGE 304
V C G E++L C + +++ G + P + + + + +
Sbjct: 1437 VRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSEST 1496
Query: 305 ARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQ 364
+RL G GRVEVL +WGTVCD WD + A+VVCR+LG G A A A+ GQ
Sbjct: 1497 LALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQ 1556
Query: 365 GMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRC-----------------N 407
G G I L +VRCSG E LW CPH + +C H +DAGV C N
Sbjct: 1557 GSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTN 1616
Query: 408 LP--YTGAET--RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLG 463
LP G+E+ +RL G + GRVEV G WG +C D W T +A V CRQLG
Sbjct: 1617 LPALTVGSESSLALRLVNGGDRCRGRVEVLYRG----SWGTVCDDSWDTNDANVVCRQLG 1672
Query: 464 LGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHG--THITCKRTGTRFTAG 521
G+A + +V+ VRC+G E L C H G TH G AG
Sbjct: 1673 CGWAMSAPGNARFGQGSG--PIVLDDVRCSGNESYLWSCPHKGWLTH----NCGHHEDAG 1726
Query: 522 VICSET 527
VICS T
Sbjct: 1727 VICSAT 1732
Score = 263 bits (672), Expect = 4e-70
Identities = 176/507 (34%), Positives = 234/507 (46%), Gaps = 35/507 (6%)
Query: 28 SPSTGPEKKAGSQGLRFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELG 87
SP E S LR G GRVE+ G WGT+CDD + A+++CR+LG
Sbjct: 220 SPPVPTEGSESSLALRLVNGG---DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLG 276
Query: 88 FTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQ 147
A +A++G G+G I LD++ CSG E + C GW +C H EDAGVIC
Sbjct: 277 CGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAP 336
Query: 148 RLPGFSDSNVIEVEHHLQV---EEVRIRPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKG 204
+ + H + +R G R +G VEV W VCD
Sbjct: 337 QSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDR-----CQGRVEVLYRGSWGTVCDDS 391
Query: 205 WSAHNSHVVCGMLG--FPSEKRVNAAFYRLLAQRQQHSFGLHGVACVGTEAHLSLCSLEF 262
W +++VVC LG + + NA F + L V C G E++L C
Sbjct: 392 WDTSDANVVCRQLGCGWATSAPGNARF-----GQGSGPIVLDDVRCSGYESYLWSCPHNG 446
Query: 263 YRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKPQGEARVRLKGGAHPGEGRVEV 322
+ +++ G +P AS+ + + +RL G +GRVEV
Sbjct: 447 WLSHNCQHSEDAGVICSDTLPTITLPASTVGSESSLA-------LRLVNGGDRCQGRVEV 499
Query: 323 LKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELS 382
L +WGTVCD WD + A+VVCR+LG G A A AR GQG G I L +VRCSG E
Sbjct: 500 LYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESY 559
Query: 383 LWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRW 442
LW CPH + +C HS+DAGV C+ P + R+ G R Q GRVEV G W
Sbjct: 560 LWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVNGGDRCQ--GRVEVLYRG----SW 613
Query: 443 GLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQC 502
G +C D W T +A V CRQLG G+A + +V+ VRC+G E L C
Sbjct: 614 GTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSG--PIVLDDVRCSGHESYLWSC 671
Query: 503 AHHGTHITCKRTGTRFTAGVICSETAS 529
++G G AGVICS S
Sbjct: 672 PNNGW--LSHNCGHHEDAGVICSAAQS 696
Score = 262 bits (670), Expect = 8e-70
Identities = 172/504 (34%), Positives = 240/504 (47%), Gaps = 47/504 (9%)
Query: 55 EGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSC 114
+GRVE+ G WGT+CDD + A+++CR+LG AT +A++G G+G I LD++ C
Sbjct: 602 QGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 661
Query: 115 SGTEQSVTECASRGWGNSDCTHDEDAGVIC---KDQRLPGFSDSNVIEVEHHLQVEE--V 169
SG E + C + GW + +C H EDAGVIC + + P + I + E +
Sbjct: 662 SGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPSTVGSESSL 721
Query: 170 RIRPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLG--FPSEKRVNA 227
+R G R +G VEV W VCD W ++++VVC LG + + NA
Sbjct: 722 TLRLVNGSDR-----CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNA 776
Query: 228 AFYRLLAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVY 287
F + L V C G E++L C + +++ G P
Sbjct: 777 RF-----GQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPTP 831
Query: 288 AASSGQKKQQQSK-PQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCR 346
+ + + P+ +RL G +GRVEVL +WGTVCD WD A+VVCR
Sbjct: 832 SPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCR 891
Query: 347 ELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRC 406
+LG G A A AR GQG G I L +VRCSG E LW CPH + +C HS+DAGV C
Sbjct: 892 QLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVIC 951
Query: 407 NLPYT-------------------GAET--RIRLSGGRSQHEGRVEVQIGGPGPLRWGLI 445
+ ++ G+E+ +RL G + +GRVEV G WG +
Sbjct: 952 SAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQG----SWGTV 1007
Query: 446 CGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHH 505
C D W T +A V CRQLG G+A + +V+ VRC+G E L C H+
Sbjct: 1008 CDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSG--PIVLDDVRCSGHESYLWSCPHN 1065
Query: 506 GTHITCKRTGTRFTAGVICSETAS 529
G G AGVICS + S
Sbjct: 1066 GW--LSHNCGHSEDAGVICSASQS 1087
Score = 262 bits (669), Expect = 1e-69
Identities = 190/553 (34%), Positives = 257/553 (46%), Gaps = 43/553 (7%)
Query: 5 SVWQWSPWGLLLCLLCSSCLGS--PSPST--GPEKKAGSQGLRFRLAGFPRKPYEGRVEI 60
+V + SP L L + GS PS ST + GL RL + +GRVEI
Sbjct: 59 TVAEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGR-CQGRVEI 117
Query: 61 QRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQS 120
G WGT+CDD + A+++CR+LG A +A +G G+G I LD++ CSG E
Sbjct: 118 LYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESY 177
Query: 121 VTECASRGWGNSDCTHDEDAGVICKDQRLPGF--SDSNVIEVEHHLQVE----EVRIRPA 174
+ C GW + +C H EDAGVIC + +S + + + E + +R
Sbjct: 178 LWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLV 237
Query: 175 VGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGML--GFPSEKRVNAAFYRL 232
G R G VEV W VCD W ++++VVC L G+ NA F
Sbjct: 238 NGGDR-----CRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQF--- 289
Query: 233 LAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSG 292
+ L V C G E++L C + ++ G + P + +
Sbjct: 290 --GQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTW 347
Query: 293 QKKQQQSK-PQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFG 351
+ P+ +RL G +GRVEVL +WGTVCD WD A+VVCR+LG G
Sbjct: 348 PTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCG 407
Query: 352 SAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCN---- 407
A A AR GQG G I L +VRCSG E LW CPH + +C HS+DAGV C+
Sbjct: 408 WATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSDTLP 467
Query: 408 ---LPYT--GAET--RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACR 460
LP + G+E+ +RL G + +GRVEV G WG +C D W T +A V CR
Sbjct: 468 TITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRG----SWGTVCDDSWDTNDANVVCR 523
Query: 461 QLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHGTHITCKRTGTRFTA 520
QLG G+A + +V+ VRC+G E L C H+G G A
Sbjct: 524 QLGCGWAMLAPGNARFGQGSG--PIVLDDVRCSGNESYLWSCPHNGW--LSHNCGHSEDA 579
Query: 521 GVICSETASDLLL 533
GVICS S L L
Sbjct: 580 GVICSGPESSLAL 592
Score = 261 bits (666), Expect = 2e-69
Identities = 181/544 (33%), Positives = 248/544 (45%), Gaps = 52/544 (9%)
Query: 18 LLCSSCLG--SPSPSTGPEKKAGSQGLRFRLA-----GFPRKPYEGRVEIQRAGEWGTIC 70
++CS+ +PSP T P A + G LA G R +GRVE+ G WGT+C
Sbjct: 1080 VICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDR--CQGRVEVLYRGSWGTVC 1137
Query: 71 DDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWG 130
DD + A+++CR+LG A +A++G G+G I LD++ CSG E + C GW
Sbjct: 1138 DDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWL 1197
Query: 131 NSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQV---EEVRIRPAVGWGRRPLPVTEG 187
+ +C H EDAGVIC + + H + +R G R +G
Sbjct: 1198 SHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDR-----CQG 1252
Query: 188 LVEVRLPDGWSQVCDKGWSAHNSHVVCGML--GFPSEKRVNAAFYRLLAQRQQHSFGLHG 245
VEV W VCD W ++++VVC L G+ + NA F + L
Sbjct: 1253 RVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARF-----GQGSGPIVLDD 1307
Query: 246 VACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSK-PQGE 304
V C G E++L C + +++ G + P + + + +
Sbjct: 1308 VRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESS 1367
Query: 305 ARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQ 364
+RL G +GRVEVL +WGTVCD WD + A+VVCR+LG G A A AR GQ
Sbjct: 1368 LALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQ 1427
Query: 365 GMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNL------------PYTG 412
G G I L +VRCSG E LW CPH + +C H +DAGV C+ P +
Sbjct: 1428 GSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSR 1487
Query: 413 AET-------RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLG 465
A T +RL G + GRVEV G WG +C D W T +A V CRQLG G
Sbjct: 1488 ASTAGSESTLALRLVNGGDRCRGRVEVLYQG----SWGTVCDDYWDTNDANVVCRQLGCG 1543
Query: 466 YANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAGVICS 525
+A + +V+ VRC+G E L C H+G G AGVICS
Sbjct: 1544 WAMSAPGNAQFGQGSG--PIVLDDVRCSGHESYLWSCPHNGW--LSHNCGHHEDAGVICS 1599
Query: 526 ETAS 529
S
Sbjct: 1600 AAQS 1603
Score = 211 bits (538), Expect = 2e-54
Identities = 143/416 (34%), Positives = 193/416 (46%), Gaps = 33/416 (7%)
Query: 18 LLCSSCLGSPSPS--TGPEKKAGSQGLRFRLA-----GFPRKPYEGRVEIQRAGEWGTIC 70
++CS+ P+PS T P A + G LA G R +GRVE+ G WGT+C
Sbjct: 1338 VICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDR--CQGRVEVLYRGSWGTVC 1395
Query: 71 DDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWG 130
DD + A+++CR+LG AT +A++G G+G I LD++ CSG E + C GW
Sbjct: 1396 DDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWL 1455
Query: 131 NSDCTHDEDAGVIC---KDQRLPGFSDSNVIEVEHHLQVEEVRIRPAVGWGRRPLPVTEG 187
+ +C H EDAGVIC + Q P + +R G R G
Sbjct: 1456 SHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDR-----CRG 1510
Query: 188 LVEVRLPDGWSQVCDKGWSAHNSHVVCGMLG--FPSEKRVNAAFYRLLAQRQQHSFGLHG 245
VEV W VCD W ++++VVC LG + NA F + L
Sbjct: 1511 RVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQF-----GQGSGPIVLDD 1565
Query: 246 VACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKP---- 301
V C G E++L C + +++ C A V C + + P
Sbjct: 1566 VRCSGHESYLWSCPHNGWLSHN---CGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTV 1622
Query: 302 --QGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSG 359
+ +RL G GRVEVL +WGTVCD WD + A+VVCR+LG G A A
Sbjct: 1623 GSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGN 1682
Query: 360 ARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAET 415
AR GQG G I L +VRCSG E LW CPHK +C H +DAGV C+ + T
Sbjct: 1683 ARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTT 1738
Score = 190 bits (482), Expect = 5e-48
Identities = 128/380 (33%), Positives = 175/380 (46%), Gaps = 42/380 (11%)
Query: 186 EGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLG--FPSEKRVNAAFYRLLAQRQQHSFGL 243
+G VE+ W VCD W ++++VVC LG + NA F + L
Sbjct: 112 QGRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWF-----GQGSGPIAL 166
Query: 244 HGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKP-- 301
V C G E++L C + +++ G + P S + P
Sbjct: 167 DDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTE 226
Query: 302 --QGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSG 359
+ +RL G GRVEVL +WGTVCD WD + A+VVCR+LG G A A
Sbjct: 227 GSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGN 286
Query: 360 ARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYT-------- 411
A+ GQG G I L +VRCSG E LW CPH +C HS+DAGV C+ P +
Sbjct: 287 AQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDT 346
Query: 412 ---------GAETRI--RLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACR 460
G E+ + RL G + +GRVEV G WG +C D W T +A V CR
Sbjct: 347 WPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGS----WGTVCDDSWDTSDANVVCR 402
Query: 461 QLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHG--THITCKRTGTRF 518
QLG G+A + +V+ VRC+G E L C H+G +H C+ +
Sbjct: 403 QLGCGWATSAPGNARFGQGSG--PIVLDDVRCSGYESYLWSCPHNGWLSH-NCQHSED-- 457
Query: 519 TAGVICSETASDLLLHSALV 538
AGVICS+T + L ++ V
Sbjct: 458 -AGVICSDTLPTITLPASTV 476
Score = 107 bits (266), Expect = 5e-23
Identities = 46/94 (48%), Positives = 63/94 (67%)
Query: 56 GRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCS 115
GRVEI G WGT+CDD +T+Q A ++CR+LG A +A +G G+G I LD++ CS
Sbjct: 1887 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1946
Query: 116 GTEQSVTECASRGWGNSDCTHDEDAGVICKDQRL 149
GTE ++ +C +RGW + +C H EDAGVIC L
Sbjct: 1947 GTESTLWQCRNRGWFSHNCNHREDAGVICSGNHL 1980
Score = 99.8 bits (247), Expect = 8e-21
Identities = 44/90 (48%), Positives = 57/90 (63%)
Query: 318 GRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCS 377
GRVE+ TWGTVCD W + A VVCR+LG G A AL A G G G I L +V CS
Sbjct: 1887 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1946
Query: 378 GQELSLWKCPHKNITAEDCSHSQDAGVRCN 407
G E +LW+C ++ + +C+H +DAGV C+
Sbjct: 1947 GTESTLWQCRNRGWFSHNCNHREDAGVICS 1976
Score = 63.9 bits (154), Expect = 5e-10
Identities = 41/98 (41%), Positives = 50/98 (51%), Gaps = 8/98 (8%)
Query: 428 GRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVM 487
GRVE+ GG WG +C D W EA V CRQLG G A L Y+ SG+ + +
Sbjct: 1887 GRVEIYHGGT----WGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNA-YFGSGS-GPITL 1940
Query: 488 SGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAGVICS 525
V C+GTE +L QC + G R AGVICS
Sbjct: 1941 DDVECSGTESTLWQCRNRGWF--SHNCNHREDAGVICS 1976
Score = 34.7 bits (78), Expect = 0.34
Identities = 23/72 (31%), Positives = 28/72 (38%), Gaps = 3/72 (4%)
Query: 187 GLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFGLHGV 246
G VE+ W VCD W+ + VVC LG R +A L V
Sbjct: 1887 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGC---GRAVSALGNAYFGSGSGPITLDDV 1943
Query: 247 ACVGTEAHLSLC 258
C GTE+ L C
Sbjct: 1944 ECSGTESTLWQC 1955
>gi|148539842 deleted in malignant brain tumors 1 isoform b precursor
[Homo sapiens]
Length = 2413
Score = 264 bits (675), Expect = 2e-70
Identities = 180/536 (33%), Positives = 245/536 (45%), Gaps = 52/536 (9%)
Query: 26 SPSPSTGPEKKAGSQGLRFRLA-----GFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAH 80
+PSP T P A + G LA G R +GRVE+ G WGT+CDD + A+
Sbjct: 840 TPSPDTWPTSHASTAGPESSLALRLVNGGDR--CQGRVEVLYRGSWGTVCDDSWDTSDAN 897
Query: 81 ILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDA 140
++CR+LG AT +A++G G+G I LD++ CSG E + C GW + +C H EDA
Sbjct: 898 VVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDA 957
Query: 141 GVICKDQRL-----PGFSDSNVIEVEHHLQVEEVRIRPAVGWGRRPLPVTEGLVEVRLPD 195
GVIC P + + + +R G R +G VEV
Sbjct: 958 GVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDR-----CQGRVEVLYQG 1012
Query: 196 GWSQVCDKGWSAHNSHVVCGMLG--FPSEKRVNAAFYRLLAQRQQHSFGLHGVACVGTEA 253
W VCD W ++++VVC LG + NA F + L V C G E+
Sbjct: 1013 SWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARF-----GQGSGPIVLDDVRCSGHES 1067
Query: 254 HLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSK-PQGEARVRLKGG 312
+L C + +++ G + P + + + + +RL G
Sbjct: 1068 YLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNG 1127
Query: 313 AHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLS 372
+GRVEVL +WGTVCD WD + A+VVCR+LG G A A AR GQG G I L
Sbjct: 1128 GDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLD 1187
Query: 373 EVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNL------------PYTGAET----- 415
+VRCSG E LW CPH + +C H +DAGV C+ P + A T
Sbjct: 1188 DVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSES 1247
Query: 416 --RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQE 473
+RL G + +GRVEV G WG +C D W T +A V CRQLG G+A
Sbjct: 1248 SLALRLVNGGDRCQGRVEVLYRG----SWGTVCDDYWDTNDANVVCRQLGCGWATSAPGN 1303
Query: 474 TWYWDSGNITEVVMSGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAGVICSETAS 529
+ +V+ VRC+G E L C H+G G AGVICS + S
Sbjct: 1304 ARFGQGSG--PIVLDDVRCSGHESYLWSCPHNGW--LSHNCGHHEDAGVICSASQS 1355
Score = 264 bits (675), Expect = 2e-70
Identities = 185/546 (33%), Positives = 252/546 (46%), Gaps = 58/546 (10%)
Query: 18 LLCSSCLGSPSPS--TGPEKKAGSQGLRFRLA-----GFPRKPYEGRVEIQRAGEWGTIC 70
++CS+ P+PS T P A + G LA G R +GRVE+ G WGT+C
Sbjct: 1219 VICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDR--CQGRVEVLYRGSWGTVC 1276
Query: 71 DDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWG 130
DD + A+++CR+LG AT +A++G G+G I LD++ CSG E + C GW
Sbjct: 1277 DDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWL 1336
Query: 131 NSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQV---EEVRIRPAVGWGRRPLPVTEG 187
+ +C H EDAGVIC + + H + +R G R +G
Sbjct: 1337 SHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDR-----CQG 1391
Query: 188 LVEVRLPDGWSQVCDKGWSAHNSHVVCGML--GFPSEKRVNAAFYRLLAQRQQHSFGLHG 245
VEV W VCD W ++++VVC L G+ + NA F + L
Sbjct: 1392 RVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARF-----GQGSGPIVLDD 1446
Query: 246 VACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASS-GQKKQQQSKPQGE 304
V C G E++L C + +++ G + P + + + + +
Sbjct: 1447 VRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSEST 1506
Query: 305 ARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQ 364
+RL G GRVEVL +WGTVCD WD + A+VVCR+LG G A A A+ GQ
Sbjct: 1507 LALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQ 1566
Query: 365 GMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRC-----------------N 407
G G I L +VRCSG E LW CPH + +C H +DAGV C N
Sbjct: 1567 GSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTN 1626
Query: 408 LP--YTGAET--RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLG 463
LP G+E+ +RL G + GRVEV G WG +C D W T +A V CRQLG
Sbjct: 1627 LPALTVGSESSLALRLVNGGDRCRGRVEVLYRG----SWGTVCDDSWDTNDANVVCRQLG 1682
Query: 464 LGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHG--THITCKRTGTRFTAG 521
G+A + +V+ VRC+G E L C H G TH G AG
Sbjct: 1683 CGWAMSAPGNARFGQGSG--PIVLDDVRCSGNESYLWSCPHKGWLTH----NCGHHEDAG 1736
Query: 522 VICSET 527
VICS T
Sbjct: 1737 VICSAT 1742
Score = 262 bits (670), Expect = 8e-70
Identities = 178/513 (34%), Positives = 236/513 (46%), Gaps = 37/513 (7%)
Query: 28 SPSTGPEKKAGSQGLRFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELG 87
SP E S LR G GRVE+ G WGT+CDD + A+++CR+LG
Sbjct: 220 SPPVPTEGSESSLALRLVNGG---DRCRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLG 276
Query: 88 FTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQ 147
A +A++G G+G I LD++ CSG E + C GW +C H EDAGVIC
Sbjct: 277 CGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAP 336
Query: 148 RLPGFSDSNVIEVEHHLQV---EEVRIRPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKG 204
+ + H + +R G R +G VEV W VCD
Sbjct: 337 QSRPTPSPDTWPTSHASTAGPESSLALRLVNGGDR-----CQGRVEVLYRGSWGTVCDDS 391
Query: 205 WSAHNSHVVCGMLG--FPSEKRVNAAFYRLLAQRQQHSFGLHGVACVGTEAHLSLCSLEF 262
W +++VVC LG + + NA F + L V C G E++L C
Sbjct: 392 WDTSDANVVCRQLGCGWATSAPGNARF-----GQGSGPIVLDDVRCSGYESYLWSCPHNG 446
Query: 263 YRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKP------QGEARVRLKGGAHPG 316
+ +++ C A V C ++ S + P + +RL G
Sbjct: 447 WLSHN---CQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRC 503
Query: 317 EGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRC 376
+GRVEVL +WGTVCD WD + A+VVCR+LG G A A AR GQG G I L +VRC
Sbjct: 504 QGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRC 563
Query: 377 SGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGG 436
SG E LW CPH + +C HS+DAGV C+ P + R+ G R Q GRVEV G
Sbjct: 564 SGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSLALRLVNGGDRCQ--GRVEVLYRG 621
Query: 437 PGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTE 496
WG +C D W T +A V CRQLG G+A + +V+ VRC+G E
Sbjct: 622 ----SWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSG--PIVLDDVRCSGHE 675
Query: 497 LSLDQCAHHGTHITCKRTGTRFTAGVICSETAS 529
L C ++G G AGVICS S
Sbjct: 676 SYLWSCPNNGW--LSHNCGHHEDAGVICSAAQS 706
Score = 262 bits (670), Expect = 8e-70
Identities = 172/504 (34%), Positives = 240/504 (47%), Gaps = 47/504 (9%)
Query: 55 EGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSC 114
+GRVE+ G WGT+CDD + A+++CR+LG AT +A++G G+G I LD++ C
Sbjct: 612 QGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 671
Query: 115 SGTEQSVTECASRGWGNSDCTHDEDAGVIC---KDQRLPGFSDSNVIEVEHHLQVEE--V 169
SG E + C + GW + +C H EDAGVIC + + P + I + E +
Sbjct: 672 SGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTLSTITLPPSTVGSESSL 731
Query: 170 RIRPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLG--FPSEKRVNA 227
+R G R +G VEV W VCD W ++++VVC LG + + NA
Sbjct: 732 TLRLVNGSDR-----CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNA 786
Query: 228 AFYRLLAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVY 287
F + L V C G E++L C + +++ G P
Sbjct: 787 RF-----GQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSVSQSRPTP 841
Query: 288 AASSGQKKQQQSK-PQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCR 346
+ + + P+ +RL G +GRVEVL +WGTVCD WD A+VVCR
Sbjct: 842 SPDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCR 901
Query: 347 ELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRC 406
+LG G A A AR GQG G I L +VRCSG E LW CPH + +C HS+DAGV C
Sbjct: 902 QLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVIC 961
Query: 407 NLPYT-------------------GAET--RIRLSGGRSQHEGRVEVQIGGPGPLRWGLI 445
+ ++ G+E+ +RL G + +GRVEV G WG +
Sbjct: 962 SAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQG----SWGTV 1017
Query: 446 CGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHH 505
C D W T +A V CRQLG G+A + +V+ VRC+G E L C H+
Sbjct: 1018 CDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSG--PIVLDDVRCSGHESYLWSCPHN 1075
Query: 506 GTHITCKRTGTRFTAGVICSETAS 529
G G AGVICS + S
Sbjct: 1076 GW--LSHNCGHSEDAGVICSASQS 1097
Score = 261 bits (666), Expect = 2e-69
Identities = 181/544 (33%), Positives = 248/544 (45%), Gaps = 52/544 (9%)
Query: 18 LLCSSCLG--SPSPSTGPEKKAGSQGLRFRLA-----GFPRKPYEGRVEIQRAGEWGTIC 70
++CS+ +PSP T P A + G LA G R +GRVE+ G WGT+C
Sbjct: 1090 VICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDR--CQGRVEVLYRGSWGTVC 1147
Query: 71 DDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWG 130
DD + A+++CR+LG A +A++G G+G I LD++ CSG E + C GW
Sbjct: 1148 DDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWL 1207
Query: 131 NSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQV---EEVRIRPAVGWGRRPLPVTEG 187
+ +C H EDAGVIC + + H + +R G R +G
Sbjct: 1208 SHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDR-----CQG 1262
Query: 188 LVEVRLPDGWSQVCDKGWSAHNSHVVCGML--GFPSEKRVNAAFYRLLAQRQQHSFGLHG 245
VEV W VCD W ++++VVC L G+ + NA F + L
Sbjct: 1263 RVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARF-----GQGSGPIVLDD 1317
Query: 246 VACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSK-PQGE 304
V C G E++L C + +++ G + P + + + +
Sbjct: 1318 VRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESS 1377
Query: 305 ARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQ 364
+RL G +GRVEVL +WGTVCD WD + A+VVCR+LG G A A AR GQ
Sbjct: 1378 LALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQ 1437
Query: 365 GMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNL------------PYTG 412
G G I L +VRCSG E LW CPH + +C H +DAGV C+ P +
Sbjct: 1438 GSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSR 1497
Query: 413 AET-------RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLG 465
A T +RL G + GRVEV G WG +C D W T +A V CRQLG G
Sbjct: 1498 ASTAGSESTLALRLVNGGDRCRGRVEVLYQG----SWGTVCDDYWDTNDANVVCRQLGCG 1553
Query: 466 YANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAGVICS 525
+A + +V+ VRC+G E L C H+G G AGVICS
Sbjct: 1554 WAMSAPGNAQFGQGSG--PIVLDDVRCSGHESYLWSCPHNGW--LSHNCGHHEDAGVICS 1609
Query: 526 ETAS 529
S
Sbjct: 1610 AAQS 1613
Score = 259 bits (661), Expect = 8e-69
Identities = 188/563 (33%), Positives = 256/563 (45%), Gaps = 53/563 (9%)
Query: 5 SVWQWSPWGLLLCLLCSSCLGS--PSPST--GPEKKAGSQGLRFRLAGFPRKPYEGRVEI 60
+V + SP L L + GS PS ST + GL RL + +GRVEI
Sbjct: 59 TVAEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGR-CQGRVEI 117
Query: 61 QRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQS 120
G WGT+CDD + A+++CR+LG A +A +G G+G I LD++ CSG E
Sbjct: 118 LYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESY 177
Query: 121 VTECASRGWGNSDCTHDEDAGVICKDQRLPGF--SDSNVIEVEHHLQVE----EVRIRPA 174
+ C GW + +C H EDAGVIC + +S + + + E + +R
Sbjct: 178 LWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLV 237
Query: 175 VGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGML--GFPSEKRVNAAFYRL 232
G R G VEV W VCD W ++++VVC L G+ NA F
Sbjct: 238 NGGDR-----CRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQF--- 289
Query: 233 LAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSG 292
+ L V C G E++L C + ++ G + P + +
Sbjct: 290 --GQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTW 347
Query: 293 QKKQQQSK-PQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFG 351
+ P+ +RL G +GRVEVL +WGTVCD WD A+VVCR+LG G
Sbjct: 348 PTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCG 407
Query: 352 SAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYT 411
A A AR GQG G I L +VRCSG E LW CPH + +C HS+DAGV C+ ++
Sbjct: 408 WATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHS 467
Query: 412 -------------------GAET--RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDW 450
G+E+ +RL G + +GRVEV G WG +C D W
Sbjct: 468 WSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRG----SWGTVCDDSW 523
Query: 451 GTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHGTHIT 510
T +A V CRQLG G+A + +V+ VRC+G E L C H+G
Sbjct: 524 DTNDANVVCRQLGCGWAMLAPGNARFGQGSG--PIVLDDVRCSGNESYLWSCPHNGW--L 579
Query: 511 CKRTGTRFTAGVICSETASDLLL 533
G AGVICS S L L
Sbjct: 580 SHNCGHSEDAGVICSGPESSLAL 602
Score = 211 bits (538), Expect = 2e-54
Identities = 143/416 (34%), Positives = 193/416 (46%), Gaps = 33/416 (7%)
Query: 18 LLCSSCLGSPSPS--TGPEKKAGSQGLRFRLA-----GFPRKPYEGRVEIQRAGEWGTIC 70
++CS+ P+PS T P A + G LA G R +GRVE+ G WGT+C
Sbjct: 1348 VICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDR--CQGRVEVLYRGSWGTVC 1405
Query: 71 DDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWG 130
DD + A+++CR+LG AT +A++G G+G I LD++ CSG E + C GW
Sbjct: 1406 DDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWL 1465
Query: 131 NSDCTHDEDAGVIC---KDQRLPGFSDSNVIEVEHHLQVEEVRIRPAVGWGRRPLPVTEG 187
+ +C H EDAGVIC + Q P + +R G R G
Sbjct: 1466 SHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDR-----CRG 1520
Query: 188 LVEVRLPDGWSQVCDKGWSAHNSHVVCGMLG--FPSEKRVNAAFYRLLAQRQQHSFGLHG 245
VEV W VCD W ++++VVC LG + NA F + L
Sbjct: 1521 RVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQF-----GQGSGPIVLDD 1575
Query: 246 VACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKP---- 301
V C G E++L C + +++ C A V C + + P
Sbjct: 1576 VRCSGHESYLWSCPHNGWLSHN---CGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTV 1632
Query: 302 --QGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSG 359
+ +RL G GRVEVL +WGTVCD WD + A+VVCR+LG G A A
Sbjct: 1633 GSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGN 1692
Query: 360 ARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAET 415
AR GQG G I L +VRCSG E LW CPHK +C H +DAGV C+ + T
Sbjct: 1693 ARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTT 1748
Score = 107 bits (266), Expect = 5e-23
Identities = 46/94 (48%), Positives = 63/94 (67%)
Query: 56 GRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCS 115
GRVEI G WGT+CDD +T+Q A ++CR+LG A +A +G G+G I LD++ CS
Sbjct: 1897 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1956
Query: 116 GTEQSVTECASRGWGNSDCTHDEDAGVICKDQRL 149
GTE ++ +C +RGW + +C H EDAGVIC L
Sbjct: 1957 GTESTLWQCRNRGWFSHNCNHREDAGVICSGNHL 1990
Score = 99.8 bits (247), Expect = 8e-21
Identities = 44/90 (48%), Positives = 57/90 (63%)
Query: 318 GRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCS 377
GRVE+ TWGTVCD W + A VVCR+LG G A AL A G G G I L +V CS
Sbjct: 1897 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1956
Query: 378 GQELSLWKCPHKNITAEDCSHSQDAGVRCN 407
G E +LW+C ++ + +C+H +DAGV C+
Sbjct: 1957 GTESTLWQCRNRGWFSHNCNHREDAGVICS 1986
Score = 63.9 bits (154), Expect = 5e-10
Identities = 41/98 (41%), Positives = 50/98 (51%), Gaps = 8/98 (8%)
Query: 428 GRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVM 487
GRVE+ GG WG +C D W EA V CRQLG G A L Y+ SG+ + +
Sbjct: 1897 GRVEIYHGGT----WGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNA-YFGSGS-GPITL 1950
Query: 488 SGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAGVICS 525
V C+GTE +L QC + G R AGVICS
Sbjct: 1951 DDVECSGTESTLWQCRNRGWF--SHNCNHREDAGVICS 1986
Score = 34.7 bits (78), Expect = 0.34
Identities = 23/72 (31%), Positives = 28/72 (38%), Gaps = 3/72 (4%)
Query: 187 GLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFGLHGV 246
G VE+ W VCD W+ + VVC LG R +A L V
Sbjct: 1897 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGC---GRAVSALGNAYFGSGSGPITLDDV 1953
Query: 247 ACVGTEAHLSLC 258
C GTE+ L C
Sbjct: 1954 ECSGTESTLWQC 1965
>gi|148539840 deleted in malignant brain tumors 1 isoform a
precursor [Homo sapiens]
Length = 1785
Score = 264 bits (675), Expect = 2e-70
Identities = 180/536 (33%), Positives = 245/536 (45%), Gaps = 52/536 (9%)
Query: 26 SPSPSTGPEKKAGSQGLRFRLA-----GFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAH 80
+PSP T P A + G LA G R +GRVE+ G WGT+CDD + A+
Sbjct: 341 TPSPDTWPTSHASTAGPESSLALRLVNGGDR--CQGRVEVLYRGSWGTVCDDSWDTSDAN 398
Query: 81 ILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDA 140
++CR+LG AT +A++G G+G I LD++ CSG E + C GW + +C H EDA
Sbjct: 399 VVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDA 458
Query: 141 GVICKDQRL-----PGFSDSNVIEVEHHLQVEEVRIRPAVGWGRRPLPVTEGLVEVRLPD 195
GVIC P + + + +R G R +G VEV
Sbjct: 459 GVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDR-----CQGRVEVLYQG 513
Query: 196 GWSQVCDKGWSAHNSHVVCGMLG--FPSEKRVNAAFYRLLAQRQQHSFGLHGVACVGTEA 253
W VCD W ++++VVC LG + NA F + L V C G E+
Sbjct: 514 SWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARF-----GQGSGPIVLDDVRCSGHES 568
Query: 254 HLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSK-PQGEARVRLKGG 312
+L C + +++ G + P + + + + +RL G
Sbjct: 569 YLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNG 628
Query: 313 AHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLS 372
+GRVEVL +WGTVCD WD + A+VVCR+LG G A A AR GQG G I L
Sbjct: 629 GDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLD 688
Query: 373 EVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNL------------PYTGAET----- 415
+VRCSG E LW CPH + +C H +DAGV C+ P + A T
Sbjct: 689 DVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSES 748
Query: 416 --RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQE 473
+RL G + +GRVEV G WG +C D W T +A V CRQLG G+A
Sbjct: 749 SLALRLVNGGDRCQGRVEVLYRG----SWGTVCDDYWDTNDANVVCRQLGCGWATSAPGN 804
Query: 474 TWYWDSGNITEVVMSGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAGVICSETAS 529
+ +V+ VRC+G E L C H+G G AGVICS + S
Sbjct: 805 ARFGQGSG--PIVLDDVRCSGHESYLWSCPHNGW--LSHNCGHHEDAGVICSASQS 856
Score = 262 bits (669), Expect = 1e-69
Identities = 184/546 (33%), Positives = 251/546 (45%), Gaps = 58/546 (10%)
Query: 18 LLCSSCLG--SPSPSTGPEKKAGSQGLRFRLA-----GFPRKPYEGRVEIQRAGEWGTIC 70
++CS+ +PSP T P A + G LA G R +GRVE+ G WGT+C
Sbjct: 591 VICSASQSRPTPSPDTWPTSHASTAGSESSLALRLVNGGDR--CQGRVEVLYRGSWGTVC 648
Query: 71 DDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWG 130
DD + A+++CR+LG A +A++G G+G I LD++ CSG E + C GW
Sbjct: 649 DDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWL 708
Query: 131 NSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQV---EEVRIRPAVGWGRRPLPVTEG 187
+ +C H EDAGVIC + + H + +R G R +G
Sbjct: 709 SHNCGHHEDAGVICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDR-----CQG 763
Query: 188 LVEVRLPDGWSQVCDKGWSAHNSHVVCGML--GFPSEKRVNAAFYRLLAQRQQHSFGLHG 245
VEV W VCD W ++++VVC L G+ + NA F + L
Sbjct: 764 RVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWATSAPGNARF-----GQGSGPIVLDD 818
Query: 246 VACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASS-GQKKQQQSKPQGE 304
V C G E++L C + +++ G + P + + + + +
Sbjct: 819 VRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSEST 878
Query: 305 ARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQ 364
+RL G GRVEVL +WGTVCD WD + A+VVCR+LG G A A A+ GQ
Sbjct: 879 LALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQ 938
Query: 365 GMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRC-----------------N 407
G G I L +VRCSG E LW CPH + +C H +DAGV C N
Sbjct: 939 GSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTN 998
Query: 408 LP--YTGAET--RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLG 463
LP G+E+ +RL G + GRVEV G WG +C D W T +A V CRQLG
Sbjct: 999 LPALTVGSESSLALRLVNGGDRCRGRVEVLYRG----SWGTVCDDSWDTNDANVVCRQLG 1054
Query: 464 LGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHG--THITCKRTGTRFTAG 521
G+A + +V+ VRC+G E L C H G TH G AG
Sbjct: 1055 CGWAMSAPGNARFGQGSG--PIVLDDVRCSGNESYLWSCPHKGWLTH----NCGHHEDAG 1108
Query: 522 VICSET 527
VICS T
Sbjct: 1109 VICSAT 1114
Score = 257 bits (657), Expect = 2e-68
Identities = 186/559 (33%), Positives = 255/559 (45%), Gaps = 53/559 (9%)
Query: 5 SVWQWSPWGLLLCLLCSSCLGS--PSPST--GPEKKAGSQGLRFRLAGFPRKPYEGRVEI 60
+V + SP L L + GS PS ST + GL RL + +GRVEI
Sbjct: 59 TVAEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGR-CQGRVEI 117
Query: 61 QRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQS 120
G WGT+CDD + A+++CR+LG A +A +G G+G I LD++ CSG E
Sbjct: 118 LYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESY 177
Query: 121 VTECASRGWGNSDCTHDEDAGVICKDQRLPGF--SDSNVIEVEHHLQVE----EVRIRPA 174
+ C GW + +C H EDAGVIC + +S + + + E + +R
Sbjct: 178 LWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLV 237
Query: 175 VGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLG--FPSEKRVNAAFYRL 232
G R G VEV W VCD W ++++VVC LG + NA F
Sbjct: 238 NGGDR-----CRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQF--- 289
Query: 233 LAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSG 292
+ L V C G E++L C + ++ G + P + +
Sbjct: 290 --GQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTW 347
Query: 293 QKKQQQSK-PQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFG 351
+ P+ +RL G +GRVEVL +WGTVCD WD A+VVCR+LG G
Sbjct: 348 PTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCG 407
Query: 352 SAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYT 411
A A AR GQG G I L +VRCSG E LW CPH + +C HS+DAGV C+ ++
Sbjct: 408 WATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHS 467
Query: 412 -------------------GAET--RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDW 450
G+E+ +RL G + +GRVEV G WG +C D W
Sbjct: 468 WSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYQG----SWGTVCDDSW 523
Query: 451 GTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHGTHIT 510
T +A V CRQLG G+A + +V+ VRC+G E L C H+G
Sbjct: 524 DTNDANVVCRQLGCGWAMSAPGNARFGQGSG--PIVLDDVRCSGHESYLWSCPHNGW--L 579
Query: 511 CKRTGTRFTAGVICSETAS 529
G AGVICS + S
Sbjct: 580 SHNCGHSEDAGVICSASQS 598
Score = 211 bits (538), Expect = 2e-54
Identities = 143/416 (34%), Positives = 193/416 (46%), Gaps = 33/416 (7%)
Query: 18 LLCSSCLGSPSPS--TGPEKKAGSQGLRFRLA-----GFPRKPYEGRVEIQRAGEWGTIC 70
++CS+ P+PS T P A + G LA G R +GRVE+ G WGT+C
Sbjct: 720 VICSASQSQPTPSPDTWPTSHASTAGSESSLALRLVNGGDR--CQGRVEVLYRGSWGTVC 777
Query: 71 DDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWG 130
DD + A+++CR+LG AT +A++G G+G I LD++ CSG E + C GW
Sbjct: 778 DDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWL 837
Query: 131 NSDCTHDEDAGVIC---KDQRLPGFSDSNVIEVEHHLQVEEVRIRPAVGWGRRPLPVTEG 187
+ +C H EDAGVIC + Q P + +R G R G
Sbjct: 838 SHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTLALRLVNGGDR-----CRG 892
Query: 188 LVEVRLPDGWSQVCDKGWSAHNSHVVCGMLG--FPSEKRVNAAFYRLLAQRQQHSFGLHG 245
VEV W VCD W ++++VVC LG + NA F + L
Sbjct: 893 RVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQF-----GQGSGPIVLDD 947
Query: 246 VACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKP---- 301
V C G E++L C + +++ C A V C + + P
Sbjct: 948 VRCSGHESYLWSCPHNGWLSHN---CGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTV 1004
Query: 302 --QGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSG 359
+ +RL G GRVEVL +WGTVCD WD + A+VVCR+LG G A A
Sbjct: 1005 GSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGN 1064
Query: 360 ARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAET 415
AR GQG G I L +VRCSG E LW CPHK +C H +DAGV C+ + T
Sbjct: 1065 ARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTT 1120
Score = 107 bits (266), Expect = 5e-23
Identities = 46/94 (48%), Positives = 63/94 (67%)
Query: 56 GRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCS 115
GRVEI G WGT+CDD +T+Q A ++CR+LG A +A +G G+G I LD++ CS
Sbjct: 1269 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1328
Query: 116 GTEQSVTECASRGWGNSDCTHDEDAGVICKDQRL 149
GTE ++ +C +RGW + +C H EDAGVIC L
Sbjct: 1329 GTESTLWQCRNRGWFSHNCNHREDAGVICSGNHL 1362
Score = 99.8 bits (247), Expect = 8e-21
Identities = 44/90 (48%), Positives = 57/90 (63%)
Query: 318 GRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCS 377
GRVE+ TWGTVCD W + A VVCR+LG G A AL A G G G I L +V CS
Sbjct: 1269 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1328
Query: 378 GQELSLWKCPHKNITAEDCSHSQDAGVRCN 407
G E +LW+C ++ + +C+H +DAGV C+
Sbjct: 1329 GTESTLWQCRNRGWFSHNCNHREDAGVICS 1358
Score = 63.9 bits (154), Expect = 5e-10
Identities = 41/98 (41%), Positives = 50/98 (51%), Gaps = 8/98 (8%)
Query: 428 GRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVM 487
GRVE+ GG WG +C D W EA V CRQLG G A L Y+ SG+ + +
Sbjct: 1269 GRVEIYHGGT----WGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNA-YFGSGS-GPITL 1322
Query: 488 SGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAGVICS 525
V C+GTE +L QC + G R AGVICS
Sbjct: 1323 DDVECSGTESTLWQCRNRGWF--SHNCNHREDAGVICS 1358
Score = 34.7 bits (78), Expect = 0.34
Identities = 23/72 (31%), Positives = 28/72 (38%), Gaps = 3/72 (4%)
Query: 187 GLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFGLHGV 246
G VE+ W VCD W+ + VVC LG R +A L V
Sbjct: 1269 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGC---GRAVSALGNAYFGSGSGPITLDDV 1325
Query: 247 ACVGTEAHLSLC 258
C GTE+ L C
Sbjct: 1326 ECSGTESTLWQC 1337
>gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens]
Length = 1788
Score = 261 bits (667), Expect = 2e-69
Identities = 193/556 (34%), Positives = 256/556 (46%), Gaps = 71/556 (12%)
Query: 18 LLCSSC--LGSPSPSTGPE-----KKAGSQG-LRFRLAGFPRKPYEGRVEIQRAGEWGTI 69
++CS+ +PSP T P GS+ L RL + +GRVE+ G WGT+
Sbjct: 460 VICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDR-CQGRVEVLYRGSWGTV 518
Query: 70 CDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGW 129
CDD + A+++CR+LG A +A++G G+G I LD++ CSG E + C GW
Sbjct: 519 CDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGW 578
Query: 130 GNSDCTHDEDAGVICKD-QRLPGFSDSNVIEVEHHLQV-----EEVRIRPAVGWGRRPLP 183
+ +C H EDAGVIC Q LP H LQ + +R G R
Sbjct: 579 LSHNCGHSEDAGVICSALQWLPTPIRPRSWPSSHALQTCKGPESSLALRLVNGGDR---- 634
Query: 184 VTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLG--FPSEKRVNAAFYRLLAQRQQHSF 241
+G VEV W VCD W ++++VVC LG + + NA F +
Sbjct: 635 -CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARF-----GQGSGPI 688
Query: 242 GLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKP 301
L V C G E++L C + +++ C A V C AA S + + P
Sbjct: 689 VLDDVRCSGHESYLWSCPNNGWLSHN---CGHHEDAGVICS-----AAQSRSTPRPDTWP 740
Query: 302 QGEAR---------VRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGS 352
A +RL G +GRVEVL +WGTVCD WD + A+VVCR+LG G
Sbjct: 741 TSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGW 800
Query: 353 AREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNL---- 408
A A AR GQG G I L +VRCSG E LW CPH + +C HS+DAGV C+
Sbjct: 801 AMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSR 860
Query: 409 --------PYTGAET-------RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTL 453
P + A T +RL G + GRVEV G WG +C D W T
Sbjct: 861 PTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQG----SWGTVCDDYWDTN 916
Query: 454 EAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHGTHITCKR 513
+A V CRQLG G+A + +V+ VRC+G E L C H+G
Sbjct: 917 DANVVCRQLGCGWAMSAPGNAQFGQGSG--PIVLDDVRCSGHESYLWSCPHNGW--LSHN 972
Query: 514 TGTRFTAGVICSETAS 529
G AGVICS S
Sbjct: 973 CGHHEDAGVICSAAQS 988
Score = 260 bits (665), Expect = 3e-69
Identities = 172/502 (34%), Positives = 234/502 (46%), Gaps = 49/502 (9%)
Query: 55 EGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSC 114
+GRVE+ G WGT+CDD + A+++CR+LG AT +A++G G+G I LD++ C
Sbjct: 636 QGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 695
Query: 115 SGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQV---EEVRI 171
SG E + C + GW + +C H EDAGVIC + + H + +
Sbjct: 696 SGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLAL 755
Query: 172 RPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLG--FPSEKRVNAAF 229
R G R +G VEV W VCD W ++++VVC LG + NA F
Sbjct: 756 RLVNGGDR-----CQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARF 810
Query: 230 YRLLAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAA 289
+ L V C G E++L C + +++ G + P +
Sbjct: 811 -----GQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSP 865
Query: 290 SSGQKKQQQSK-PQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCREL 348
+ + + + +RL G GRVEVL +WGTVCD WD + A+VVCR+L
Sbjct: 866 DTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQL 925
Query: 349 GFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRC-- 406
G G A A A+ GQG G I L +VRCSG E LW CPH + +C H +DAGV C
Sbjct: 926 GCGWAMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSA 985
Query: 407 ---------------NLPY--TGAETRI--RLSGGRSQHEGRVEVQIGGPGPLRWGLICG 447
NLP G+E+ + RL G + GRVEV G WG +C
Sbjct: 986 AQSQSTPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGS----WGTVCD 1041
Query: 448 DDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHG- 506
D W T +A V CRQLG G+A + +V+ VRC+G E L C H G
Sbjct: 1042 DSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSG--PIVLDDVRCSGNESYLWSCPHKGW 1099
Query: 507 -THITCKRTGTRFTAGVICSET 527
TH G AGVICS T
Sbjct: 1100 LTH----NCGHHEDAGVICSAT 1117
Score = 253 bits (646), Expect = 5e-67
Identities = 184/555 (33%), Positives = 252/555 (45%), Gaps = 53/555 (9%)
Query: 5 SVWQWSPWGLLLCLLCSSCLGS--PSPST--GPEKKAGSQGLRFRLAGFPRKPYEGRVEI 60
+V + SP L L + GS PS ST + GL RL + +GRVEI
Sbjct: 59 TVAEGSPISLESTLESTVAEGSLIPSESTLESTVAEGSDSGLALRLVNGDGR-CQGRVEI 117
Query: 61 QRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQS 120
G WGT+CDD + A+++CR+LG A +A +G G+G I LD++ CSG E
Sbjct: 118 LYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQGSGPIALDDVRCSGHESY 177
Query: 121 VTECASRGWGNSDCTHDEDAGVICKDQRLPGF--SDSNVIEVEHHLQVE----EVRIRPA 174
+ C GW + +C H EDAGVIC + +S + + + E + +R
Sbjct: 178 LWSCPHNGWLSHNCGHGEDAGVICSAAQPQSTLRPESWPVRISPPVPTEGSESSLALRLV 237
Query: 175 VGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLG--FPSEKRVNAAFYRL 232
G R G VEV W VCD W ++++VVC LG + NA F
Sbjct: 238 NGGDR-----CRGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQF--- 289
Query: 233 LAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSG 292
+ L V C G E++L C + ++ G + P + +
Sbjct: 290 --GQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSRPTPSPDTW 347
Query: 293 QKKQQQSK-PQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFG 351
+ + +RL G +GRVEVL +WGTVCD WD A+VVCR+LG G
Sbjct: 348 PTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCG 407
Query: 352 SAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYT 411
A A AR GQG G I L +VRCSG E LW CPH + +C HS+DAGV C+ ++
Sbjct: 408 WATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHS 467
Query: 412 -------------------GAET--RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDW 450
G+E+ +RL G + +GRVEV G WG +C D W
Sbjct: 468 WSTPSPDTLPTITLPASTVGSESSLALRLVNGGDRCQGRVEVLYRG----SWGTVCDDSW 523
Query: 451 GTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHGTHIT 510
T +A V CRQLG G+A + +V+ VRC+G E L C H+G
Sbjct: 524 DTNDANVVCRQLGCGWAMLAPGNARFGQGSG--PIVLDDVRCSGNESYLWSCPHNGW--L 579
Query: 511 CKRTGTRFTAGVICS 525
G AGVICS
Sbjct: 580 SHNCGHSEDAGVICS 594
Score = 208 bits (530), Expect = 1e-53
Identities = 142/415 (34%), Positives = 190/415 (45%), Gaps = 31/415 (7%)
Query: 18 LLCSSCLG--SPSPSTGPEKKAGSQGLRFRLA-----GFPRKPYEGRVEIQRAGEWGTIC 70
++CS+ +P P T P A + G LA G R +GRVE+ G WGT+C
Sbjct: 723 VICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDR--CQGRVEVLYQGSWGTVC 780
Query: 71 DDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWG 130
DD + A+++CR+LG A +A++G G+G I LD++ CSG E + C GW
Sbjct: 781 DDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWL 840
Query: 131 NSDCTHDEDAGVICK--DQRLPGFSDSNVIEVEHHLQVEEVRIRPAVGWGRRPLPVTEGL 188
+ +C H EDAGVIC R D+ E V G R G
Sbjct: 841 SHNCGHSEDAGVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDR----CRGR 896
Query: 189 VEVRLPDGWSQVCDKGWSAHNSHVVCGMLG--FPSEKRVNAAFYRLLAQRQQHSFGLHGV 246
VEV W VCD W ++++VVC LG + NA F + L V
Sbjct: 897 VEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQF-----GQGSGPIVLDDV 951
Query: 247 ACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKP----- 301
C G E++L C + +++ C A V C + + P
Sbjct: 952 RCSGHESYLWSCPHNGWLSHN---CGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVG 1008
Query: 302 -QGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGA 360
+ +RL G GRVEVL +WGTVCD WD + A+VVCR+LG G A A A
Sbjct: 1009 SESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNA 1068
Query: 361 RMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAET 415
R GQG G I L +VRCSG E LW CPHK +C H +DAGV C+ + T
Sbjct: 1069 RFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICSATQINSTT 1123
Score = 107 bits (266), Expect = 5e-23
Identities = 46/94 (48%), Positives = 63/94 (67%)
Query: 56 GRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCS 115
GRVEI G WGT+CDD +T+Q A ++CR+LG A +A +G G+G I LD++ CS
Sbjct: 1272 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1331
Query: 116 GTEQSVTECASRGWGNSDCTHDEDAGVICKDQRL 149
GTE ++ +C +RGW + +C H EDAGVIC L
Sbjct: 1332 GTESTLWQCRNRGWFSHNCNHREDAGVICSGNHL 1365
Score = 99.8 bits (247), Expect = 8e-21
Identities = 44/90 (48%), Positives = 57/90 (63%)
Query: 318 GRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCS 377
GRVE+ TWGTVCD W + A VVCR+LG G A AL A G G G I L +V CS
Sbjct: 1272 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1331
Query: 378 GQELSLWKCPHKNITAEDCSHSQDAGVRCN 407
G E +LW+C ++ + +C+H +DAGV C+
Sbjct: 1332 GTESTLWQCRNRGWFSHNCNHREDAGVICS 1361
Score = 63.9 bits (154), Expect = 5e-10
Identities = 41/98 (41%), Positives = 50/98 (51%), Gaps = 8/98 (8%)
Query: 428 GRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVM 487
GRVE+ GG WG +C D W EA V CRQLG G A L Y+ SG+ + +
Sbjct: 1272 GRVEIYHGGT----WGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNA-YFGSGS-GPITL 1325
Query: 488 SGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAGVICS 525
V C+GTE +L QC + G R AGVICS
Sbjct: 1326 DDVECSGTESTLWQCRNRGWF--SHNCNHREDAGVICS 1361
Score = 34.7 bits (78), Expect = 0.34
Identities = 23/72 (31%), Positives = 28/72 (38%), Gaps = 3/72 (4%)
Query: 187 GLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFGLHGV 246
G VE+ W VCD W+ + VVC LG R +A L V
Sbjct: 1272 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGC---GRAVSALGNAYFGSGSGPITLDDV 1328
Query: 247 ACVGTEAHLSLC 258
C GTE+ L C
Sbjct: 1329 ECSGTESTLWQC 1340
>gi|20149540 lysyl oxidase preproprotein [Homo sapiens]
Length = 417
Score = 226 bits (576), Expect = 6e-59
Identities = 106/202 (52%), Positives = 137/202 (67%), Gaps = 3/202 (1%)
Query: 530 DLLLHSALVQETAYIEDRPLHMLYCAAEENCLASSARSANW-PYGHRRLLRFSSQIHNLG 588
DL+ +Q + Y++ ++ L CAAEENCLAS+A A+ Y HR LLRF ++ N G
Sbjct: 214 DLVADPYYIQASTYVQKMSMYNLRCAAEENCLASTAYRADVRDYDHRVLLRFPQRVKNQG 273
Query: 589 RADFRPKAGRHSWVWHECHGHYHSMDIFTHYDILTPNGTK-VAEGHKASFCLEDTECQED 647
+DF P R+SW WH CH HYHSMD F+HYD+L N + VAEGHKASFCLEDT C
Sbjct: 274 TSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDANTQRRVAEGHKASFCLEDTSCDYG 333
Query: 648 VSKRYECANFGEQGITVGCWDLYRHDIDCQWIDITDVKPGNYILQVVINPNFEVAESDFT 707
+R+ C QG++ GC+D Y DIDCQWIDITDVKPGNYIL+V +NP++ V ESD+T
Sbjct: 334 YHRRFACTAH-TQGLSPGCYDTYGADIDCQWIDITDVKPGNYILKVSVNPSYLVPESDYT 392
Query: 708 NNAMKCNCKYDGHRIWVHNCHI 729
NN ++C+ +Y GH + C I
Sbjct: 393 NNVVRCDIRYTGHHAYASGCTI 414
>gi|50659091 scavenger receptor cysteine-rich type 1 precursor [Homo
sapiens]
Length = 1453
Score = 226 bits (575), Expect = 8e-59
Identities = 153/486 (31%), Positives = 222/486 (45%), Gaps = 62/486 (12%)
Query: 53 PYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNL 112
P G VE++ G+WGT+CDD + A+ ++C++LG + + G+IWLD++
Sbjct: 56 PCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRFGQAVTRHGKIWLDDV 115
Query: 113 SCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIR 172
SC G E ++ EC R WG+ +C H ED GV C + ++N+ +R
Sbjct: 116 SCYGNESALWECQHREWGSHNCYHGEDVGVNC-------YGEANL------------GLR 156
Query: 173 PAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRL 232
G G VEV+ + W +CD GW+ + + VVC LG PS +
Sbjct: 157 LVDGNNS-----CSGRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISSGVVNSP 211
Query: 233 LAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSG 292
R L + C G E L C + +D C ++C Y +S
Sbjct: 212 AVLRP---IWLDDILCQGNELALWNCRHRGWGNHD---CSHNEDVTLTC-----YDSS-- 258
Query: 293 QKKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGS 352
+ +RL GG + GRVE+ WGTVC KW+ AA VVC++LG G+
Sbjct: 259 -----------DLELRLVGGTNRCMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGT 307
Query: 353 AREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTG 412
A + G + L V CSG E LW C H DC H D V C+ G
Sbjct: 308 ALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICS---DG 364
Query: 413 AETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQ 472
A+ +RL+ G + GRVEV+I +W IC +W +A+V C+QLG ++ G +
Sbjct: 365 ADLELRLADGSNNCSGRVEVRIHE----QWWTICDQNWKNEQALVVCKQLGCPFSVFGSR 420
Query: 473 ETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHG-THITCKRTGTRFTAGVICSETAS-D 530
S ++ ++ + CTG E +L C + G TC R R AGVICS+ A D
Sbjct: 421 RA--KPSNEARDIWINSISCTGNESALWDCTYDGKAKRTCFR---RSDAGVICSDKADLD 475
Query: 531 LLLHSA 536
L L A
Sbjct: 476 LRLVGA 481
Score = 206 bits (523), Expect = 8e-53
Identities = 128/352 (36%), Positives = 170/352 (48%), Gaps = 52/352 (14%)
Query: 56 GRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCS 115
GRVEI G WGTICDD + L AH++C++LG A T SA +G G+G IWLD+L+C+
Sbjct: 1047 GRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLNCT 1106
Query: 116 GTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAV 175
G E + +C SRGWG DC H EDAGVIC S+ + + + E
Sbjct: 1107 GMESHLWQCPSRGWGQHDCRHKEDAGVIC--------SEFTALRLYSETETESCA----- 1153
Query: 176 GWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQ 235
G +EV W V + + + +VC LG
Sbjct: 1154 -----------GRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGC---------------- 1186
Query: 236 RQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKK 295
G +GV + A LS F +D +CP ++ C+ P S
Sbjct: 1187 ------GENGVVSL---APLSKTGSGFMWVDDI-QCPKTHISIWQCLSAPWERRISSPA- 1235
Query: 296 QQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSARE 355
+++ E R+R++GG GRVE+ A +WGTVCD WDL A VVC++LG GSA
Sbjct: 1236 -EETWITCEDRIRVRGGDTECSGRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALA 1294
Query: 356 ALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCN 407
AL A GQG G I L ++RC G E LW C K DC H +DAGVRC+
Sbjct: 1295 ALRDASFGQGTGTIWLDDMRCKGNESFLWDCHAKPWGQSDCGHKEDAGVRCS 1346
Score = 205 bits (522), Expect = 1e-52
Identities = 150/508 (29%), Positives = 214/508 (42%), Gaps = 73/508 (14%)
Query: 56 GRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCS 115
GR+E+ G WGT+CDD + +AA ++C +L + G G+IWLD++SC
Sbjct: 594 GRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIWLDDVSCD 653
Query: 116 GTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAV 175
G E + C + GWGN+DC+H ED GVIC D ++ +R
Sbjct: 654 GDESDLWSCRNSGWGNNDCSHSEDVGVICSD-------------------ASDMELRLVG 694
Query: 176 GWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQ 235
G R G VEV + +C GW + + VVC L S RV+
Sbjct: 695 GSSR-----CAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSR-------- 741
Query: 236 RQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKK 295
E H + +L +N + C GG ++ C+ +
Sbjct: 742 ----------------EPHFTERTLHILMSN--SGCTGGEASLWDCIRWEWKQTACHLNM 783
Query: 296 QQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSARE 355
+ + RL G P GRVEV A TW +VCD + LHAA+V+CREL G A
Sbjct: 784 EASLICSAHRQPRLVGADMPCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAIS 843
Query: 356 ALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAET 415
G G+G G + +C G E L CP + C HS++ GV C+ T
Sbjct: 844 LSVGDHFGKGNGLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCS-----RYT 898
Query: 416 RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETW 475
+RL G+SQ +G+VE+ + G WG +C W +A V CRQL G A +
Sbjct: 899 DVRLVNGKSQCDGQVEINVLG----HWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKY 954
Query: 476 YWDSGNITEVVMSGVRCTGTELSLDQC---------AHHGTHITCKRTGTRFTAGVICSE 526
+ V C G E LD C HG ++ TG+ C
Sbjct: 955 IGERS--VRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLA 1012
Query: 527 TASDLLLHSALVQETAYI--EDRPLHML 552
SD L SA+ + +A I ED+ L ++
Sbjct: 1013 NVSDPYL-SAVPEGSALICLEDKRLRLV 1039
Score = 204 bits (520), Expect = 2e-52
Identities = 149/505 (29%), Positives = 208/505 (41%), Gaps = 81/505 (16%)
Query: 39 SQGLRFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSA 98
S L RL G + GRVE++ G WGT+C + AA ++C++LG A +
Sbjct: 257 SSDLELRLVGGTNRCM-GRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGTALHFAGLP 315
Query: 99 KYGPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVI 158
G+ +WLD +SCSG E + +C G N DC H D VIC D
Sbjct: 316 HLQSGSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICSDG----------- 364
Query: 159 EVEHHLQVEEVRIRPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLG 218
++ +R A G G VEVR+ + W +CD+ W + VVC LG
Sbjct: 365 --------ADLELRLADGSNN-----CSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLG 411
Query: 219 FPSEKRVNAAFYRLLAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAV 278
P R + ++ ++C G E+ L C+ Y C A
Sbjct: 412 CPFSV---FGSRRAKPSNEARDIWINSISCTGNESALWDCT---YDGKAKRTCFRRSDAG 465
Query: 279 VSCVPGPVYAASSGQKKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDL 338
V C + + +RL G P GR+EV WGTVC +W
Sbjct: 466 VIC------------------SDKADLDLRLVGAHSPCYGRLEVKYQGEWGTVCHDRWST 507
Query: 339 HAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSH 398
A+VVC++LG G + G I L +V C G E ++W C H +C H
Sbjct: 508 RNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDDVSCIGNESNIWDCEHSGWGKHNCVH 567
Query: 399 SQDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVA 458
+D V C+ A +RL GG ++ GR+EV G RWG +C D W + A V
Sbjct: 568 REDVIVTCS---GDATWGLRLVGGSNRCSGRLEVYFQG----RWGTVCDDGWNSKAAAVV 620
Query: 459 CRQL---------GLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHG-TH 508
C QL GLG A+ G + W + V C G E L C + G +
Sbjct: 621 CSQLDCPSSIIGMGLGNASTGYGKIW-----------LDDVSCDGDESDLWSCRNSGWGN 669
Query: 509 ITCKRTGTRFTAGVICSETASDLLL 533
C + GVICS+ ASD+ L
Sbjct: 670 NDCSHSE---DVGVICSD-ASDMEL 690
Score = 195 bits (495), Expect = 1e-49
Identities = 141/462 (30%), Positives = 200/462 (43%), Gaps = 79/462 (17%)
Query: 56 GRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEA---TGWTHSAKYGPGTGR-IWLDN 111
GRVE++ WGTICDD + L A ++CR+LG + +G +S P R IWLD+
Sbjct: 166 GRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCPSSFISSGVVNS----PAVLRPIWLDD 221
Query: 112 LSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRI 171
+ C G E ++ C RGWGN DC+H+ED + C D ++ +
Sbjct: 222 ILCQGNELALWNCRHRGWGNHDCSHNEDVTLTCYDS-------------------SDLEL 262
Query: 172 RPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYR 231
R G R G VE+++ W VC W+ + VVC LG + A +
Sbjct: 263 RLVGGTNR-----CMGRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGT-----ALHFA 312
Query: 232 LLAQRQQHS--FGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAA 289
L Q S L GV+C G E+ L C + C V C G
Sbjct: 313 GLPHLQSGSDVVWLDGVSCSGNESFLWDCR---HSGTVNFDCLHQNDVSVICSDG----- 364
Query: 290 SSGQKKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELG 349
+ +RL G++ GRVEV W T+CD+ W A VVC++LG
Sbjct: 365 -------------ADLELRLADGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLG 411
Query: 350 -----FGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGV 404
FGS R A+ I ++ + C+G E +LW C + C DAGV
Sbjct: 412 CPFSVFGSRR-----AKPSNEARDIWINSISCTGNESALWDCTYDGKAKRTCFRRSDAGV 466
Query: 405 RCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGL 464
C+ A+ +RL G S GR+EV+ G WG +C D W T A V C+QLG
Sbjct: 467 ICS---DKADLDLRLVGAHSPCYGRLEVKYQG----EWGTVCHDRWSTRNAAVVCKQLGC 519
Query: 465 GYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHG 506
G H T++ ++ + + V C G E ++ C H G
Sbjct: 520 GKPMHVFGMTYFKEASG--PIWLDDVSCIGNESNIWDCEHSG 559
Score = 194 bits (494), Expect = 2e-49
Identities = 133/447 (29%), Positives = 199/447 (44%), Gaps = 57/447 (12%)
Query: 56 GRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCS 115
GRVE++ +W TICD ++ + A ++C++LG + + AK IW++++SC+
Sbjct: 380 GRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCPFSVFGSRRAKPSNEARDIWINSISCT 439
Query: 116 GTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAV 175
G E ++ +C G C DAGVIC D+ +D ++ V H
Sbjct: 440 GNESALWDCTYDGKAKRTCFRRSDAGVICSDK-----ADLDLRLVGAHSPCY-------- 486
Query: 176 GWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQ 235
G +EV+ W VC WS N+ VVC LG V Y +
Sbjct: 487 -----------GRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTY---FK 532
Query: 236 RQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKK 295
L V+C+G E+++ C + ++ C +V+C +
Sbjct: 533 EASGPIWLDDVSCIGNESNIWDCEHSGWGKHN---CVHREDVIVTCSGDATWG------- 582
Query: 296 QQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSARE 355
+RL GG++ GR+EV WGTVCD W+ AA+VVC +L S+
Sbjct: 583 -----------LRLVGGSNRCSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSII 631
Query: 356 ALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAET 415
+ G G I L +V C G E LW C + DCSHS+D GV C+ ++
Sbjct: 632 GMGLGNASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVICS---DASDM 688
Query: 416 RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETW 475
+RL GG S+ G+VEV + G G++C + WG A V CRQL G A +E
Sbjct: 689 ELRLVGGSSRCAGKVEVNVQG----AVGILCANGWGMNIAEVVCRQLECGSAIRVSREPH 744
Query: 476 YWDSGNITEVVMSGVRCTGTELSLDQC 502
+ + ++MS CTG E SL C
Sbjct: 745 FTE--RTLHILMSNSGCTGGEASLWDC 769
Score = 192 bits (488), Expect = 1e-48
Identities = 133/463 (28%), Positives = 198/463 (42%), Gaps = 56/463 (12%)
Query: 53 PYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNL 112
P GRVE++ A W ++CD DF+L AA++LCREL +A + +G G G W +
Sbjct: 803 PCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNGLTWAEKF 862
Query: 113 SCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIR 172
C G+E + C C H + GV+C ++D ++ +
Sbjct: 863 QCEGSETHLALCPIVQHPEDTCIHSREVGVVCS-----RYTDVRLVNGKSQ--------- 908
Query: 173 PAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRL 232
+G VE+ + W +CD W ++ V+C L + Y
Sbjct: 909 ------------CDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKY-- 954
Query: 233 LAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSC---VPGPVYAA 289
+ +R +G H C+G E+ L C + A C G V C + P++
Sbjct: 955 IGERSVRVWG-HRFHCLGNESLLDNCQMTVLGA---PPCIHGNTVSVICTGSLTQPLFPC 1010
Query: 290 SSGQKKQQQSK-PQGEA-------RVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAA 341
+ S P+G A R+RL G GRVE+ WGT+CD WDL A
Sbjct: 1011 LANVSDPYLSAVPEGSALICLEDKRLRLVDGDSRCAGRVEIYHDGFWGTICDDGWDLSDA 1070
Query: 342 SVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQD 401
VVC++LG G A A A G+G G I L ++ C+G E LW+CP + DC H +D
Sbjct: 1071 HVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKED 1130
Query: 402 AGVRCNLPYTGAETRIRLSGGRSQHE--GRVEVQIGGPGPLRWGLICGDDWGTLEAMVAC 459
AGV C+ T +RL GR+EV G WG + + T A + C
Sbjct: 1131 AGVICS-----EFTALRLYSETETESCAGRLEVFYNG----TWGSVGRRNITTAIAGIVC 1181
Query: 460 RQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQC 502
RQLG G +G+ + + ++C T +S+ QC
Sbjct: 1182 RQLGCG--ENGVVSLAPLSKTGSGFMWVDDIQCPKTHISIWQC 1222
Score = 160 bits (406), Expect = 3e-39
Identities = 135/484 (27%), Positives = 193/484 (39%), Gaps = 60/484 (12%)
Query: 55 EGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSC 114
+G+VEI G WG++CD + + A +LCR+L A T G + R+W C
Sbjct: 910 DGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGERSVRVWGHRFHC 969
Query: 115 SGTEQSVTECASRGWGNSDCTHDEDAGVICKDQR-------LPGFSD---SNVIEVEHHL 164
G E + C G C H VIC L SD S V E +
Sbjct: 970 LGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSAVPEGSALI 1029
Query: 165 QVEEVRIRPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKR 224
+E+ R+R G R G VE+ W +CD GW ++HVVC LG
Sbjct: 1030 CLEDKRLRLVDGDSR-----CAGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLG------ 1078
Query: 225 VNAAFYRLLAQRQQHSFG---LHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSC 281
AF ++ G L + C G E+HL C + +D C A V C
Sbjct: 1079 CGVAFNATVSAHFGEGSGPIWLDDLNCTGMESHLWQCPSRGWGQHD---CRHKEDAGVIC 1135
Query: 282 VPGPVYAASSGQKKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAA 341
S + S+ + E+ GR+EV TWG+V R A
Sbjct: 1136 --------SEFTALRLYSETETESCA----------GRLEVFYNGTWGSVGRRNITTAIA 1177
Query: 342 SVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQD 401
+VCR+LG G G G + + +++C +S+W+C S +++
Sbjct: 1178 GIVCRQLGCGENGVVSLAPLSKTGSGFMWVDDIQCPKTHISIWQCLSAPWERRISSPAEE 1237
Query: 402 AGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQ 461
+ C E RIR+ GG ++ GRVE+ G WG +C D W EA V C+Q
Sbjct: 1238 TWITC-------EDRIRVRGGDTECSGRVEIWHAGS----WGTVCDDSWDLAEAEVVCQQ 1286
Query: 462 LGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAG 521
LG G A L++ + + + +RC G E L C H G + AG
Sbjct: 1287 LGCGSALAALRDASFGQGTG--TIWLDDMRCKGNESFLWDC--HAKPWGQSDCGHKEDAG 1342
Query: 522 VICS 525
V CS
Sbjct: 1343 VRCS 1346
Score = 155 bits (392), Expect = 1e-37
Identities = 121/429 (28%), Positives = 171/429 (39%), Gaps = 64/429 (14%)
Query: 42 LRFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYG 101
L RL G P GR+E++ GEWGT+C D ++ + A ++C++LG + +
Sbjct: 474 LDLRLVG-AHSPCYGRLEVKYQGEWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFK 532
Query: 102 PGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVE 161
+G IWLD++SC G E ++ +C GWG +C H ED V C G
Sbjct: 533 EASGPIWLDDVSCIGNESNIWDCEHSGWGKHNCVHREDVIVTCSGDATWGLR-------- 584
Query: 162 HHLQVEEVRIRPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPS 221
VG R G +EV W VCD GW++ + VVC L PS
Sbjct: 585 ------------LVGGSNR----CSGRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPS 628
Query: 222 EKRVNAAFYRLLAQRQQHSFG---LHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAV 278
+ + +G L V+C G E+ L C + ND C
Sbjct: 629 ------SIIGMGLGNASTGYGKIWLDDVSCDGDESDLWSCRNSGWGNND---CSHSEDVG 679
Query: 279 VSCVPGPVYAASSGQKKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDL 338
V C + +RL GG+ G+VEV G +C W +
Sbjct: 680 VIC------------------SDASDMELRLVGGSSRCAGKVEVNVQGAVGILCANGWGM 721
Query: 339 HAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSH 398
+ A VVCR+L GSA + I +S C+G E SLW C C
Sbjct: 722 NIAEVVCRQLECGSAIRVSREPHFTERTLHILMSNSGCTGGEASLWDCIRWEWKQTACHL 781
Query: 399 SQDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVA 458
+ +A + C+ A + RL G GRVEV+ W +C D+ A V
Sbjct: 782 NMEASLICS-----AHRQPRLVGADMPCSGRVEVKHAD----TWRSVCDSDFSLHAANVL 832
Query: 459 CRQLGLGYA 467
CR+L G A
Sbjct: 833 CRELNCGDA 841
Score = 145 bits (367), Expect = 1e-34
Identities = 130/500 (26%), Positives = 189/500 (37%), Gaps = 92/500 (18%)
Query: 56 GRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCS 115
G+VE+ G G +C + + + A ++CR+L A + + T I + N C+
Sbjct: 701 GKVEVNVQGAVGILCANGWGMNIAEVVCRQLECGSAIRVSREPHFTERTLHILMSNSGCT 760
Query: 116 GTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAV 175
G E S+ +C W + C + +A +IC R P +++
Sbjct: 761 GGEASLWDCIRWEWKQTACHLNMEASLICSAHRQPRLVGADM------------------ 802
Query: 176 GWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGML--GFPSEKRVNAAFYRLL 233
G VEV+ D W VCD +S H ++V+C L G V F +
Sbjct: 803 --------PCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGN 854
Query: 234 AQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQ 293
F C G+E HL+LC + DT C V C
Sbjct: 855 GLTWAEKF-----QCEGSETHLALCPI-VQHPEDT--CIHSREVGVVC------------ 894
Query: 294 KKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSA 353
VRL G +G+VE+ WG++CD WD A V+CR+L G+A
Sbjct: 895 --------SRYTDVRLVNGKSQCDGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTA 946
Query: 354 REALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRC------- 406
G +G+ + C G E L C + A C H V C
Sbjct: 947 LSTTGGKYIGERSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVICTGSLTQP 1006
Query: 407 --------NLPYTGA-----------ETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICG 447
+ PY A + R+RL G S+ GRVE+ G WG IC
Sbjct: 1007 LFPCLANVSDPYLSAVPEGSALICLEDKRLRLVDGDSRCAGRVEIYHDG----FWGTICD 1062
Query: 448 DDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHG- 506
D W +A V C++LG G A + + + + + + CTG E L QC G
Sbjct: 1063 DGWDLSDAHVVCQKLGCGVAFNATVSAHFGEGSG--PIWLDDLNCTGMESHLWQCPSRGW 1120
Query: 507 THITCKRTGTRFTAGVICSE 526
C+ + AGVICSE
Sbjct: 1121 GQHDCRH---KEDAGVICSE 1137
Score = 122 bits (307), Expect = 9e-28
Identities = 74/208 (35%), Positives = 103/208 (49%), Gaps = 19/208 (9%)
Query: 304 EARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMG 363
+ +RL G P G VEV WGTVCD W+ A++VVC++LG + + R G
Sbjct: 45 DLELRLVNGDGPCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLG---CPFSFAMFRFG 101
Query: 364 QGM---GAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLS 420
Q + G I L +V C G E +LW+C H+ + +C H +D GV C Y A +RL
Sbjct: 102 QAVTRHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNC---YGEANLGLRLV 158
Query: 421 GGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGL--GYANHGLQETWYWD 478
G + GRVEV+ RWG IC D W A V CRQLG + + G+ +
Sbjct: 159 DGNNSCSGRVEVKF----QERWGTICDDGWNLNTAAVVCRQLGCPSSFISSGVVNS---- 210
Query: 479 SGNITEVVMSGVRCTGTELSLDQCAHHG 506
+ + + + C G EL+L C H G
Sbjct: 211 PAVLRPIWLDDILCQGNELALWNCRHRG 238
Score = 108 bits (269), Expect = 2e-23
Identities = 47/101 (46%), Positives = 62/101 (61%)
Query: 56 GRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCS 115
GRVEI AG WGT+CDD + L A ++C++LG A A +G GTG IWLD++ C
Sbjct: 1257 GRVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDMRCK 1316
Query: 116 GTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSN 156
G E + +C ++ WG SDC H EDAGV C Q L + S+
Sbjct: 1317 GNESFLWDCHAKPWGQSDCGHKEDAGVRCSGQSLKSLNASS 1357
Score = 49.7 bits (117), Expect = 1e-05
Identities = 31/105 (29%), Positives = 48/105 (45%), Gaps = 16/105 (15%)
Query: 410 YTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYA-- 467
+ G + +RL G G VEV+ G +WG +C D W T + V C+QLG ++
Sbjct: 41 FNGTDLELRLVNGDGPCSGTVEVKFQG----QWGTVCDDGWNTTASTVVCKQLGCPFSFA 96
Query: 468 --NHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHH--GTH 508
G T + ++ + V C G E +L +C H G+H
Sbjct: 97 MFRFGQAVTRH------GKIWLDDVSCYGNESALWECQHREWGSH 135
>gi|18152779 scavenger receptor cysteine rich domain containing,
group B (4 domains) [Homo sapiens]
Length = 575
Score = 224 bits (570), Expect = 3e-58
Identities = 165/513 (32%), Positives = 224/513 (43%), Gaps = 70/513 (13%)
Query: 45 RLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGT 104
RL G P + GR+E+ G WG++CDDD+ + A+++CR+LG A +G G
Sbjct: 59 RLVGGPSR-CRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVPRPLAFGQGR 117
Query: 105 GRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHL 164
G I LDN+ C G E +++EC SRGWG +C H ED V+C D+ LP + +
Sbjct: 118 GPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLC-DEFLPTQPPTRKMLTSRAP 176
Query: 165 QV------EEVRIRPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLG 218
E +R G + +G VE+ W VCD W ++ VVC LG
Sbjct: 177 PTTLPNGKSEGSVRLVGGAN-----LCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLG 231
Query: 219 FPSEKRVNA-AFYRLLAQRQQHSFGLHGVACVGTEAHLSLC-SLEF------YRANDTAR 270
+ AF+ H L V C G E L+ C SL + + + A
Sbjct: 232 CGAAMAATTNAFF---GYGTGHIL-LDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGAL 287
Query: 271 CPGGGPAVVSCVPGPVY-----------AASSGQKKQQQSK---------PQGEARVRLK 310
C G GP ++ +P A G + +++ + R+RL
Sbjct: 288 CAGLGPPTLTALPSSATREDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLV 347
Query: 311 GGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIH 370
GG P GRVEVL A WGTVCD WD A V CRE G G A A G G G +
Sbjct: 348 GGPGPCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATGLGHFGYGRGPVL 407
Query: 371 LSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLP--------YTGAET------- 415
L V C+G E L C H +C H +DAG C P G+ET
Sbjct: 408 LDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPR 467
Query: 416 ----RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGL 471
+RL G + EGRVE+ +G RWG +C D W A V CRQLG G A
Sbjct: 468 PRDGHLRLVNGAHRCEGRVELYLG----QRWGTVCDDAWDLRAAGVLCRQLGCGQALAAP 523
Query: 472 QETWYWDSGNITEVVMSGVRCTGTELSLDQCAH 504
E + +++ V+C G E +L C+H
Sbjct: 524 GEAHFGPGRG--PILLDNVKCRGEESALLLCSH 554
Score = 198 bits (503), Expect = 2e-50
Identities = 137/388 (35%), Positives = 172/388 (44%), Gaps = 50/388 (12%)
Query: 55 EGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSC 114
+GRVEI +G WGT+CDDD+ L A ++CR+LG A T +A +G GTG I LDN+ C
Sbjct: 199 QGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGYGTGHILLDNVHC 258
Query: 115 SGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFS--DSNVIEVEHHLQVE----- 167
G E + C S GWG +C H EDAG +C P + S+ + Q +
Sbjct: 259 EGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQTDPSATG 318
Query: 168 -------EVRIRPAVGW------GRRPLP----VTEGLVEVRLPDGWSQVCDKGWSAHNS 210
E + W GR L G VEV GW VCD W ++
Sbjct: 319 VGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDDWDFADA 378
Query: 211 HVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFG-------LHGVACVGTEAHLSLCSLEFY 263
V C G L FG L V C GTEA LS C F+
Sbjct: 379 RVACREAGCGPA----------LGATGLGHFGYGRGPVLLDNVGCAGTEARLSDC---FH 425
Query: 264 RANDTARCPGGGPAVVSCVPGP----VYAASSGQKKQQQSKPQG-EARVRLKGGAHPGEG 318
C A C GP + G + + P+ + +RL GAH EG
Sbjct: 426 LGWGQHNCGHHEDAGALCA-GPEELGLQVQQDGSETTRVPTPRPRDGHLRLVNGAHRCEG 484
Query: 319 RVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSG 378
RVE+ WGTVCD WDL AA V+CR+LG G A A A G G G I L V+C G
Sbjct: 485 RVELYLGQRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHFGPGRGPILLDNVKCRG 544
Query: 379 QELSLWKCPHKNITAEDCSHSQDAGVRC 406
+E +L C H A +C HS+DA V C
Sbjct: 545 EESALLLCSHIRWDAHNCDHSEDASVLC 572
Score = 143 bits (361), Expect = 5e-34
Identities = 121/387 (31%), Positives = 156/387 (40%), Gaps = 59/387 (15%)
Query: 187 GLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHS-FGLHG 245
G +EV W VCD W +++VVC LG V R LA Q L
Sbjct: 69 GRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVP----RPLAFGQGRGPILLDN 124
Query: 246 VACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPG-PVYAASSGQKKQQQSKPQG- 303
V C G EA LS C + ++ +P P + + P G
Sbjct: 125 VECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTRKMLTSRAPPTTLPNGK 184
Query: 304 -EARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARM 362
E VRL GGA+ +GRVE+L + WGTVCD W L A+VVCR+LG G+A A + A
Sbjct: 185 SEGSVRLVGGANLCQGRVEILHSGLWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFF 244
Query: 363 GQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNL-------------- 408
G G G I L V C G E L C +C H +DAG C
Sbjct: 245 GYGTGHILLDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSAT 304
Query: 409 ----------------PYTGAETRIRLSGG--RSQHEGRVEVQIGGPGPLR--------- 441
P ET + + + GR+ + +GGPGP R
Sbjct: 305 REDWAWQTDPSATGVGPQPSRETALLTTAAWAAGKKSGRLRL-VGGPGPCRGRVEVLHAG 363
Query: 442 -WGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLD 500
WG +C DDW +A VACR+ G G A G ++ G V++ V C GTE L
Sbjct: 364 GWGTVCDDDWDFADARVACREAGCGPAL-GATGLGHFGYGR-GPVLLDNVGCAGTEARLS 421
Query: 501 QCAH--HGTHITCKRTGTRFTAGVICS 525
C H G H G AG +C+
Sbjct: 422 DCFHLGWGQH----NCGHHEDAGALCA 444
Score = 132 bits (333), Expect = 9e-31
Identities = 85/250 (34%), Positives = 116/250 (46%), Gaps = 31/250 (12%)
Query: 298 QSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREAL 357
Q P +RL GG GR+EV+ +WG+VCD WD+ A+VVCR+LG G A
Sbjct: 49 QPTPLPFQELRLVGGPSRCRGRLEVMHGGSWGSVCDDDWDVVDANVVCRQLGCGLALPVP 108
Query: 358 SGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCN---------- 407
GQG G I L V C GQE +L +C + +C H +D V C+
Sbjct: 109 RPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVLCDEFLPTQPPTR 168
Query: 408 -----------LPYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAM 456
LP +E +RL GG + +GRVE+ G WG +C DDWG +A
Sbjct: 169 KMLTSRAPPTTLPNGKSEGSVRLVGGANLCQGRVEILHSG----LWGTVCDDDWGLPDAA 224
Query: 457 VACRQLGLGYANHGLQETWY-WDSGNITEVVMSGVRCTGTELSLDQCAHHGTHITCKRTG 515
V CRQLG G A ++ + +G+I ++ V C G E L C G + G
Sbjct: 225 VVCRQLGCGAAMAATTNAFFGYGTGHI---LLDNVHCEGGEPRLAACQSLGWGV--HNCG 279
Query: 516 TRFTAGVICS 525
AG +C+
Sbjct: 280 HHEDAGALCA 289
Score = 127 bits (318), Expect = 5e-29
Identities = 88/256 (34%), Positives = 112/256 (43%), Gaps = 27/256 (10%)
Query: 37 AGSQGLRFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTH 96
AG + R RL G P P GRVE+ AG WGT+CDDD+ A + CRE G A G T
Sbjct: 337 AGKKSGRLRLVGGPG-PCRGRVEVLHAGGWGTVCDDDWDFADARVACREAGCGPALGATG 395
Query: 97 SAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSN 156
+G G G + LDN+ C+GTE +++C GWG +C H EDAG +C G
Sbjct: 396 LGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHNCGHHEDAGALCAGPEELGLQ--- 452
Query: 157 VIEVEHHLQVEEVRIRPAVGWGR--RPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVC 214
++ + RP G R EG VE+ L W VCD W + V+C
Sbjct: 453 -VQQDGSETTRVPTPRPRDGHLRLVNGAHRCEGRVELYLGQRWGTVCDDAWDLRAAGVLC 511
Query: 215 GMLGFPSEKRVNAAFYRLLAQRQQHSFG-------LHGVACVGTEAHLSLCSLEFYRAND 267
LG + LA + FG L V C G E+ L LCS + D
Sbjct: 512 RQLGCG----------QALAAPGEAHFGPGRGPILLDNVKCRGEESALLLCS---HIRWD 558
Query: 268 TARCPGGGPAVVSCVP 283
C A V C P
Sbjct: 559 AHNCDHSEDASVLCQP 574
>gi|67782346 lysyl oxidase-like 1 preproprotein [Homo sapiens]
Length = 574
Score = 222 bits (565), Expect = 1e-57
Identities = 109/202 (53%), Positives = 133/202 (65%), Gaps = 3/202 (1%)
Query: 530 DLLLHSALVQETAYIEDRPLHMLYCAAEENCLASSARSAN-WPYGHRRLLRFSSQIHNLG 588
DL+ VQ + Y++ L+ L CAAEE CLAS+A + Y R LLRF ++ N G
Sbjct: 371 DLVPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYAPEATDYDVRVLLRFPQRVKNQG 430
Query: 589 RADFRPKAGRHSWVWHECHGHYHSMDIFTHYDIL-TPNGTKVAEGHKASFCLEDTECQED 647
ADF P RH+W WH CH HYHSMD F+HYD+L G KVAEGHKASFCLED+ C
Sbjct: 431 TADFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDAATGKKVAEGHKASFCLEDSTCDFG 490
Query: 648 VSKRYECANFGEQGITVGCWDLYRHDIDCQWIDITDVKPGNYILQVVINPNFEVAESDFT 707
KRY C + QG++ GC+D Y DIDCQWIDITDV+PGNYIL+V +NP + V ESDFT
Sbjct: 491 NLKRYACTSH-TQGLSPGCYDTYNADIDCQWIDITDVQPGNYILKVHVNPKYIVLESDFT 549
Query: 708 NNAMKCNCKYDGHRIWVHNCHI 729
NN ++CN Y G + NC I
Sbjct: 550 NNVVRCNIHYTGRYVSATNCKI 571
>gi|44889963 CD163 antigen isoform b [Homo sapiens]
Length = 1121
Score = 212 bits (539), Expect = 1e-54
Identities = 151/504 (29%), Positives = 230/504 (45%), Gaps = 87/504 (17%)
Query: 10 SPWGLLLCLLCSSCLGSPSPSTGPEKKAGSQGLRFRLAGFPRKPYEGRVEIQRAGEWGTI 69
SP+ + + LL S+C + S G RL K GRVE++ EWGT+
Sbjct: 25 SPFTITVVLLLSACFVTSS--------LGGTDKELRLVDGENK-CSGRVEVKVQEEWGTV 75
Query: 70 CDDDFTLQAAHILCRELGFT---EATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECAS 126
C++ ++++A ++C +LG +A GW +S+ G+GRIW+D++SC G E ++ +C
Sbjct: 76 CNNGWSMEAVSVICNQLGCPTAIKAPGWANSSA---GSGRIWMDHVSCRGNESALWDCKH 132
Query: 127 RGWG-NSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAVGWGRRPLPVT 185
GWG +S+CTH +DAGV C D SN+ E+R+ R +
Sbjct: 133 DGWGKHSNCTHQQDAGVTCSD-------GSNL----------EMRL-------TRGGNMC 168
Query: 186 EGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFG--- 242
G +E++ W VCD ++ ++ V+C L S + + +FG
Sbjct: 169 SGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGS----------SNFGEGS 218
Query: 243 ----LHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQ 298
+ C G E+ L C + + ++ C A V C G
Sbjct: 219 GPIWFDDLICNGNESALWNCKHQGWGKHN---CDHAEDAGVICSKG-------------- 261
Query: 299 SKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALS 358
+ +RL G GR+EV WGT+CD WD + A+V C++LG +A A+
Sbjct: 262 ----ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIG 317
Query: 359 GARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIR 418
+G G I L V C G E ++W+C H C+H++DAGV C+ G++ +R
Sbjct: 318 RVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCS---DGSDLELR 374
Query: 419 LSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWD 478
L GG S+ G VEV+I G +C WG EA V CRQLG G A + +
Sbjct: 375 LRGGGSRCAGTVEVEI----QRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKI 430
Query: 479 SGNITEVVMSGVRCTGTELSLDQC 502
T + +S C G E SL C
Sbjct: 431 QATNTWLFLSS--CNGNETSLWDC 452
Score = 206 bits (523), Expect = 8e-53
Identities = 136/416 (32%), Positives = 188/416 (45%), Gaps = 68/416 (16%)
Query: 20 CSSCLGSPSPSTGPEKKAGS--QGLRFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQ 77
C+S P+ T PE+ A + + + RL + GRVEI G WGTICDD + L
Sbjct: 693 CNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGR-CAGRVEIYHEGSWGTICDDSWDLS 751
Query: 78 AAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHD 137
AH++CR+LG EA T SA +G GTG IWLD + C+G E + +C S GWG +C H
Sbjct: 752 DAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHK 811
Query: 138 EDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAVGWGRRPLPVTEGLVEVRLPDGW 197
EDAGVIC + L++ R A G +EV W
Sbjct: 812 EDAGVICSEFM--------------SLRLTSEASREACA----------GRLEVFYNGAW 847
Query: 198 SQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFGLHGVACVGTEAHLSL 257
V S VVC LG + ++N A + +S+
Sbjct: 848 GTVGKSSMSETTVGVVCRQLGCADKGKINPA---------------------SLDKAMSI 886
Query: 258 CSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKPQGEA------RVRLKG 311
D +CP G P ++ S +++ + P E ++RL+
Sbjct: 887 PMWV-----DNVQCPKG--------PDTLWQCPSSPWEKRLASPSEETWITCDNKIRLQE 933
Query: 312 GAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHL 371
G GRVE+ +WGTVCD WDL A VVC++LG G A +A A GQG G I L
Sbjct: 934 GPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWL 993
Query: 372 SEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLSGGRSQHE 427
+EV+C G E SLW CP + +C H +DA V C + +T + + GRS +
Sbjct: 994 NEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCT-DISVQKTPQKATTGRSSRQ 1048
Score = 203 bits (516), Expect = 5e-52
Identities = 140/463 (30%), Positives = 197/463 (42%), Gaps = 56/463 (12%)
Query: 53 PYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNL 112
P GRVE++ WG+ICD DF+L+AA +LCREL A +G G G+IW +
Sbjct: 486 PCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEF 545
Query: 113 SCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIR 172
C G E ++ C C+H D GV+C + E+R+
Sbjct: 546 QCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCS-------------------RYTEIRLV 586
Query: 173 PAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGML--GFPSEKRVNAAFY 230
G+ P EG VE++ W +C+ W ++HV+C L G A F
Sbjct: 587 N----GKTPC---EGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFG 639
Query: 231 RLLAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAAS 290
+ Q +H F C GTE H+ C + A + CP A V C S
Sbjct: 640 KGNGQIWRHMFH-----CTGTEQHMGDCPVT---ALGASLCPSEQVASVICSGNQSQTLS 691
Query: 291 SGQKKQ----QQSKPQGEA-------RVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLH 339
S + + P+ A ++RL G GRVE+ +WGT+CD WDL
Sbjct: 692 SCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLS 751
Query: 340 AASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHS 399
A VVCR+LG G A A A G+G G I L E++C+G+E +W+C ++C H
Sbjct: 752 DAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHK 811
Query: 400 QDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVAC 459
+DAGV C+ R+ R GR+EV G WG + V C
Sbjct: 812 EDAGVICS---EFMSLRLTSEASREACAGRLEVFYNG----AWGTVGKSSMSETTVGVVC 864
Query: 460 RQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQC 502
RQLG A+ G D + + V+C +L QC
Sbjct: 865 RQLGC--ADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQC 905
Score = 198 bits (503), Expect = 2e-50
Identities = 147/473 (31%), Positives = 205/473 (43%), Gaps = 67/473 (14%)
Query: 56 GRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCS 115
GR+EI+ G WGT+CDD+F + A ++CR+L A ++ S+ +G G+G IW D+L C+
Sbjct: 170 GRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICN 229
Query: 116 GTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAV 175
G E ++ C +GWG +C H EDAGVIC + ++ +R
Sbjct: 230 GNESALWNCKHQGWGKHNCDHAEDAGVICS-------------------KGADLSLRLVD 270
Query: 176 GWGRRPLPVTE--GLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLL 233
G VTE G +EVR W +CD GW ++++ V C LG P+ A R+
Sbjct: 271 G-------VTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPT---AVTAIGRVN 320
Query: 234 AQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQ 293
A + L V+C G E + C + + C A V+C G
Sbjct: 321 ASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKH---YCNHNEDAGVTCSDG--------- 368
Query: 294 KKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSA 353
+ +RL+GG G VEV G VCDR W L A VVCR+LG GSA
Sbjct: 369 ---------SDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSA 419
Query: 354 REALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGA 413
+ L C+G E SLW C + C H ++A + C+ A
Sbjct: 420 LKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCS-----A 474
Query: 414 ETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQE 473
RL GG GRVEV+ G WG IC D+ A V CR+L G L
Sbjct: 475 HREPRLVGGDIPCSGRVEVKHGD----TWGSICDSDFSLEAASVLCRELQCGTVVSILGG 530
Query: 474 TWYWDSGNITEVVMSGVRCTGTELSLDQC-AHHGTHITCKRTGTRFTAGVICS 525
++ GN ++ +C G E L C TC + GV+CS
Sbjct: 531 A-HFGEGN-GQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSR---DVGVVCS 578
Score = 166 bits (421), Expect = 6e-41
Identities = 134/488 (27%), Positives = 204/488 (41%), Gaps = 58/488 (11%)
Query: 51 RKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLD 110
+ P EGRVE++ G WG++C+ + ++ AH+LC++L A A++G G G+IW
Sbjct: 589 KTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRH 648
Query: 111 NLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSN----------VIEV 160
C+GTEQ + +C G S C ++ A VIC + S N + E
Sbjct: 649 MFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEE 708
Query: 161 EHHLQVEEVRIRPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFP 220
+E ++R G GR G VE+ W +CD W ++HVVC LG
Sbjct: 709 SAVACIESGQLRLVNGGGR-----CAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLG-- 761
Query: 221 SEKRVNAAFYRLLAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVS 280
+ +NA + L + C G E+ + C + + C A V
Sbjct: 762 CGEAINATGSAHFGE-GTGPIWLDEMKCNGKESRIWQCHSHGWGQQN---CRHKEDAGVI 817
Query: 281 CVPGPVYAASSGQKKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHA 340
C S + S+ EA GR+EV WGTV
Sbjct: 818 C--------SEFMSLRLTSEASREACA----------GRLEVFYNGAWGTVGKSSMSETT 859
Query: 341 ASVVCRELGFGSAREALSGARMGQGMG-AIHLSEVRCSGQELSLWKCPHKNITAEDCSHS 399
VVCR+LG + ++ A + + M + + V+C +LW+CP S S
Sbjct: 860 VGVVCRQLGCAD-KGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPS 918
Query: 400 QDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVAC 459
++ + C + +IRL G + GRVE+ GG WG +C D W +A V C
Sbjct: 919 EETWITC-------DNKIRLQEGPTSCSGRVEIWHGG----SWGTVCDDSWDLDDAQVVC 967
Query: 460 RQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQC-AHHGTHITCKRTGTRF 518
+QLG G A +E + + ++ V+C G E SL C A H C G +
Sbjct: 968 QQLGCGPALKAFKEAEFGQGTG--PIWLNEVKCKGNESSLWDCPARRWGHSEC---GHKE 1022
Query: 519 TAGVICSE 526
A V C++
Sbjct: 1023 DAAVNCTD 1030
Score = 164 bits (415), Expect = 3e-40
Identities = 136/503 (27%), Positives = 193/503 (38%), Gaps = 92/503 (18%)
Query: 56 GRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCS 115
G VE++ G +CD + L+ A ++CR+LG A ++ WL SC+
Sbjct: 384 GTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCN 443
Query: 116 GTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAV 175
G E S+ +C + WG C H E+A + C R P ++
Sbjct: 444 GNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREPRLVGGDI------------------ 485
Query: 176 GWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRV--NAAFYRLL 233
G VEV+ D W +CD +S + V+C L + + A F
Sbjct: 486 --------PCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGN 537
Query: 234 AQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQ 293
Q F C G E+HLSLC + C V C
Sbjct: 538 GQIWAEEF-----QCEGHESHLSLCPVA---PRPEGTCSHSRDVGVVC------------ 577
Query: 294 KKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSA 353
+RL G P EGRVE+ WG++C+ WD+ A V+C++L G A
Sbjct: 578 --------SRYTEIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVA 629
Query: 354 REALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCN------ 407
GAR G+G G I C+G E + CP + A C Q A V C+
Sbjct: 630 LSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQT 689
Query: 408 ---------------LPYTGAET-----RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICG 447
+P A ++RL G + GRVE+ G WG IC
Sbjct: 690 LSSCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGS----WGTICD 745
Query: 448 DDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHG- 506
D W +A V CRQLG G A + + + + + ++C G E + QC HG
Sbjct: 746 DSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTG--PIWLDEMKCNGKESRIWQCHSHGW 803
Query: 507 THITCKRTGTRFTAGVICSETAS 529
C+ + AGVICSE S
Sbjct: 804 GQQNCRH---KEDAGVICSEFMS 823
Score = 160 bits (406), Expect = 3e-39
Identities = 112/349 (32%), Positives = 164/349 (46%), Gaps = 39/349 (11%)
Query: 187 GLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFGLHGV 246
G VEV++ + W VC+ GWS V+C LG P+ + A + + + H V
Sbjct: 62 GRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTA--IKAPGWANSSAGSGRIWMDH-V 118
Query: 247 ACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKPQGEAR 306
+C G E+ L C + + + + C A V+C G
Sbjct: 119 SCRGNESALWDCKHDGWGKH--SNCTHQQDAGVTCSDG------------------SNLE 158
Query: 307 VRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGM 366
+RL G + GR+E+ WGTVCD +++ ASV+CR+L GSA + G+G
Sbjct: 159 MRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGS 218
Query: 367 GAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLSGGRSQH 426
G I ++ C+G E +LW C H+ +C H++DAGV C+ GA+ +RL G ++
Sbjct: 219 GPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICS---KGADLSLRLVDGVTEC 275
Query: 427 EGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVV 486
GR+EV+ G WG IC D W + +A VAC+QLG A + S +
Sbjct: 276 SGRLEVRFQG----EWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRV--NASKGFGHIW 329
Query: 487 MSGVRCTGTELSLDQCAHH--GTHITCKRTGTRFTAGVICSETASDLLL 533
+ V C G E ++ QC HH G H C AGV CS+ SDL L
Sbjct: 330 LDSVSCQGHEPAVWQCKHHEWGKHY-CNHNE---DAGVTCSD-GSDLEL 373
Score = 58.5 bits (140), Expect = 2e-08
Identities = 60/254 (23%), Positives = 100/254 (39%), Gaps = 40/254 (15%)
Query: 51 RKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLD 110
R+ GR+E+ G WGT+ + ++CR+LG + ++ + +W+D
Sbjct: 832 REACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVD 891
Query: 111 NLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVR 170
N+ C ++ +C S W ++RL S+ I ++ ++++E
Sbjct: 892 NVQCPKGPDTLWQCPSSPW----------------EKRLASPSEETWITCDNKIRLQE-- 933
Query: 171 IRPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGF-PSEKRVNAAF 229
P GR VE+ W VCD W ++ VVC LG P+ K AF
Sbjct: 934 -GPTSCSGR---------VEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALK----AF 979
Query: 230 YRLLAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSC----VPGP 285
+ L+ V C G E+ L C R + C A V+C V
Sbjct: 980 KEAEFGQGTGPIWLNEVKCKGNESSLWDCPA---RRWGHSECGHKEDAAVNCTDISVQKT 1036
Query: 286 VYAASSGQKKQQQS 299
A++G+ +Q S
Sbjct: 1037 PQKATTGRSSRQSS 1050
>gi|44662834 CD163 antigen isoform a [Homo sapiens]
Length = 1156
Score = 212 bits (539), Expect = 1e-54
Identities = 151/504 (29%), Positives = 230/504 (45%), Gaps = 87/504 (17%)
Query: 10 SPWGLLLCLLCSSCLGSPSPSTGPEKKAGSQGLRFRLAGFPRKPYEGRVEIQRAGEWGTI 69
SP+ + + LL S+C + S G RL K GRVE++ EWGT+
Sbjct: 25 SPFTITVVLLLSACFVTSS--------LGGTDKELRLVDGENK-CSGRVEVKVQEEWGTV 75
Query: 70 CDDDFTLQAAHILCRELGFT---EATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECAS 126
C++ ++++A ++C +LG +A GW +S+ G+GRIW+D++SC G E ++ +C
Sbjct: 76 CNNGWSMEAVSVICNQLGCPTAIKAPGWANSSA---GSGRIWMDHVSCRGNESALWDCKH 132
Query: 127 RGWG-NSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAVGWGRRPLPVT 185
GWG +S+CTH +DAGV C D SN+ E+R+ R +
Sbjct: 133 DGWGKHSNCTHQQDAGVTCSD-------GSNL----------EMRL-------TRGGNMC 168
Query: 186 EGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFG--- 242
G +E++ W VCD ++ ++ V+C L S + + +FG
Sbjct: 169 SGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGS----------SNFGEGS 218
Query: 243 ----LHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQ 298
+ C G E+ L C + + ++ C A V C G
Sbjct: 219 GPIWFDDLICNGNESALWNCKHQGWGKHN---CDHAEDAGVICSKG-------------- 261
Query: 299 SKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALS 358
+ +RL G GR+EV WGT+CD WD + A+V C++LG +A A+
Sbjct: 262 ----ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIG 317
Query: 359 GARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIR 418
+G G I L V C G E ++W+C H C+H++DAGV C+ G++ +R
Sbjct: 318 RVNASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNEDAGVTCS---DGSDLELR 374
Query: 419 LSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWD 478
L GG S+ G VEV+I G +C WG EA V CRQLG G A + +
Sbjct: 375 LRGGGSRCAGTVEVEI----QRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKI 430
Query: 479 SGNITEVVMSGVRCTGTELSLDQC 502
T + +S C G E SL C
Sbjct: 431 QATNTWLFLSS--CNGNETSLWDC 452
Score = 206 bits (523), Expect = 8e-53
Identities = 136/416 (32%), Positives = 188/416 (45%), Gaps = 68/416 (16%)
Query: 20 CSSCLGSPSPSTGPEKKAGS--QGLRFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQ 77
C+S P+ T PE+ A + + + RL + GRVEI G WGTICDD + L
Sbjct: 693 CNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGR-CAGRVEIYHEGSWGTICDDSWDLS 751
Query: 78 AAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHD 137
AH++CR+LG EA T SA +G GTG IWLD + C+G E + +C S GWG +C H
Sbjct: 752 DAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHK 811
Query: 138 EDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAVGWGRRPLPVTEGLVEVRLPDGW 197
EDAGVIC + L++ R A G +EV W
Sbjct: 812 EDAGVICSEFM--------------SLRLTSEASREACA----------GRLEVFYNGAW 847
Query: 198 SQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFGLHGVACVGTEAHLSL 257
V S VVC LG + ++N A + +S+
Sbjct: 848 GTVGKSSMSETTVGVVCRQLGCADKGKINPA---------------------SLDKAMSI 886
Query: 258 CSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKPQGEA------RVRLKG 311
D +CP G P ++ S +++ + P E ++RL+
Sbjct: 887 PMWV-----DNVQCPKG--------PDTLWQCPSSPWEKRLASPSEETWITCDNKIRLQE 933
Query: 312 GAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHL 371
G GRVE+ +WGTVCD WDL A VVC++LG G A +A A GQG G I L
Sbjct: 934 GPTSCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWL 993
Query: 372 SEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLSGGRSQHE 427
+EV+C G E SLW CP + +C H +DA V C + +T + + GRS +
Sbjct: 994 NEVKCKGNESSLWDCPARRWGHSECGHKEDAAVNCT-DISVQKTPQKATTGRSSRQ 1048
Score = 203 bits (516), Expect = 5e-52
Identities = 140/463 (30%), Positives = 197/463 (42%), Gaps = 56/463 (12%)
Query: 53 PYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNL 112
P GRVE++ WG+ICD DF+L+AA +LCREL A +G G G+IW +
Sbjct: 486 PCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGNGQIWAEEF 545
Query: 113 SCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIR 172
C G E ++ C C+H D GV+C + E+R+
Sbjct: 546 QCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCS-------------------RYTEIRLV 586
Query: 173 PAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGML--GFPSEKRVNAAFY 230
G+ P EG VE++ W +C+ W ++HV+C L G A F
Sbjct: 587 N----GKTPC---EGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFG 639
Query: 231 RLLAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAAS 290
+ Q +H F C GTE H+ C + A + CP A V C S
Sbjct: 640 KGNGQIWRHMFH-----CTGTEQHMGDCPVT---ALGASLCPSEQVASVICSGNQSQTLS 691
Query: 291 SGQKKQ----QQSKPQGEA-------RVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLH 339
S + + P+ A ++RL G GRVE+ +WGT+CD WDL
Sbjct: 692 SCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLS 751
Query: 340 AASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHS 399
A VVCR+LG G A A A G+G G I L E++C+G+E +W+C ++C H
Sbjct: 752 DAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHK 811
Query: 400 QDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVAC 459
+DAGV C+ R+ R GR+EV G WG + V C
Sbjct: 812 EDAGVICS---EFMSLRLTSEASREACAGRLEVFYNG----AWGTVGKSSMSETTVGVVC 864
Query: 460 RQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQC 502
RQLG A+ G D + + V+C +L QC
Sbjct: 865 RQLGC--ADKGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQC 905
Score = 198 bits (503), Expect = 2e-50
Identities = 147/473 (31%), Positives = 205/473 (43%), Gaps = 67/473 (14%)
Query: 56 GRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCS 115
GR+EI+ G WGT+CDD+F + A ++CR+L A ++ S+ +G G+G IW D+L C+
Sbjct: 170 GRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICN 229
Query: 116 GTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAV 175
G E ++ C +GWG +C H EDAGVIC + ++ +R
Sbjct: 230 GNESALWNCKHQGWGKHNCDHAEDAGVICS-------------------KGADLSLRLVD 270
Query: 176 GWGRRPLPVTE--GLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLL 233
G VTE G +EVR W +CD GW ++++ V C LG P+ A R+
Sbjct: 271 G-------VTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPT---AVTAIGRVN 320
Query: 234 AQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQ 293
A + L V+C G E + C + + C A V+C G
Sbjct: 321 ASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKH---YCNHNEDAGVTCSDG--------- 368
Query: 294 KKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSA 353
+ +RL+GG G VEV G VCDR W L A VVCR+LG GSA
Sbjct: 369 ---------SDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSA 419
Query: 354 REALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGA 413
+ L C+G E SLW C + C H ++A + C+ A
Sbjct: 420 LKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCS-----A 474
Query: 414 ETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQE 473
RL GG GRVEV+ G WG IC D+ A V CR+L G L
Sbjct: 475 HREPRLVGGDIPCSGRVEVKHGD----TWGSICDSDFSLEAASVLCRELQCGTVVSILGG 530
Query: 474 TWYWDSGNITEVVMSGVRCTGTELSLDQC-AHHGTHITCKRTGTRFTAGVICS 525
++ GN ++ +C G E L C TC + GV+CS
Sbjct: 531 A-HFGEGN-GQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSR---DVGVVCS 578
Score = 166 bits (421), Expect = 6e-41
Identities = 134/488 (27%), Positives = 204/488 (41%), Gaps = 58/488 (11%)
Query: 51 RKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLD 110
+ P EGRVE++ G WG++C+ + ++ AH+LC++L A A++G G G+IW
Sbjct: 589 KTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRH 648
Query: 111 NLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSN----------VIEV 160
C+GTEQ + +C G S C ++ A VIC + S N + E
Sbjct: 649 MFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEE 708
Query: 161 EHHLQVEEVRIRPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFP 220
+E ++R G GR G VE+ W +CD W ++HVVC LG
Sbjct: 709 SAVACIESGQLRLVNGGGR-----CAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLG-- 761
Query: 221 SEKRVNAAFYRLLAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVS 280
+ +NA + L + C G E+ + C + + C A V
Sbjct: 762 CGEAINATGSAHFGE-GTGPIWLDEMKCNGKESRIWQCHSHGWGQQN---CRHKEDAGVI 817
Query: 281 CVPGPVYAASSGQKKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHA 340
C S + S+ EA GR+EV WGTV
Sbjct: 818 C--------SEFMSLRLTSEASREACA----------GRLEVFYNGAWGTVGKSSMSETT 859
Query: 341 ASVVCRELGFGSAREALSGARMGQGMG-AIHLSEVRCSGQELSLWKCPHKNITAEDCSHS 399
VVCR+LG + ++ A + + M + + V+C +LW+CP S S
Sbjct: 860 VGVVCRQLGCAD-KGKINPASLDKAMSIPMWVDNVQCPKGPDTLWQCPSSPWEKRLASPS 918
Query: 400 QDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVAC 459
++ + C + +IRL G + GRVE+ GG WG +C D W +A V C
Sbjct: 919 EETWITC-------DNKIRLQEGPTSCSGRVEIWHGG----SWGTVCDDSWDLDDAQVVC 967
Query: 460 RQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQC-AHHGTHITCKRTGTRF 518
+QLG G A +E + + ++ V+C G E SL C A H C G +
Sbjct: 968 QQLGCGPALKAFKEAEFGQGTG--PIWLNEVKCKGNESSLWDCPARRWGHSEC---GHKE 1022
Query: 519 TAGVICSE 526
A V C++
Sbjct: 1023 DAAVNCTD 1030
Score = 164 bits (415), Expect = 3e-40
Identities = 136/503 (27%), Positives = 193/503 (38%), Gaps = 92/503 (18%)
Query: 56 GRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCS 115
G VE++ G +CD + L+ A ++CR+LG A ++ WL SC+
Sbjct: 384 GTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCN 443
Query: 116 GTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAV 175
G E S+ +C + WG C H E+A + C R P ++
Sbjct: 444 GNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREPRLVGGDI------------------ 485
Query: 176 GWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRV--NAAFYRLL 233
G VEV+ D W +CD +S + V+C L + + A F
Sbjct: 486 --------PCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGN 537
Query: 234 AQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQ 293
Q F C G E+HLSLC + C V C
Sbjct: 538 GQIWAEEF-----QCEGHESHLSLCPVA---PRPEGTCSHSRDVGVVC------------ 577
Query: 294 KKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSA 353
+RL G P EGRVE+ WG++C+ WD+ A V+C++L G A
Sbjct: 578 --------SRYTEIRLVNGKTPCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVA 629
Query: 354 REALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCN------ 407
GAR G+G G I C+G E + CP + A C Q A V C+
Sbjct: 630 LSTPGGARFGKGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQT 689
Query: 408 ---------------LPYTGAET-----RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICG 447
+P A ++RL G + GRVE+ G WG IC
Sbjct: 690 LSSCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGS----WGTICD 745
Query: 448 DDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHG- 506
D W +A V CRQLG G A + + + + + ++C G E + QC HG
Sbjct: 746 DSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTG--PIWLDEMKCNGKESRIWQCHSHGW 803
Query: 507 THITCKRTGTRFTAGVICSETAS 529
C+ + AGVICSE S
Sbjct: 804 GQQNCRH---KEDAGVICSEFMS 823
Score = 160 bits (406), Expect = 3e-39
Identities = 112/349 (32%), Positives = 164/349 (46%), Gaps = 39/349 (11%)
Query: 187 GLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFGLHGV 246
G VEV++ + W VC+ GWS V+C LG P+ + A + + + H V
Sbjct: 62 GRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTA--IKAPGWANSSAGSGRIWMDH-V 118
Query: 247 ACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKPQGEAR 306
+C G E+ L C + + + + C A V+C G
Sbjct: 119 SCRGNESALWDCKHDGWGKH--SNCTHQQDAGVTCSDG------------------SNLE 158
Query: 307 VRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGM 366
+RL G + GR+E+ WGTVCD +++ ASV+CR+L GSA + G+G
Sbjct: 159 MRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGS 218
Query: 367 GAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLSGGRSQH 426
G I ++ C+G E +LW C H+ +C H++DAGV C+ GA+ +RL G ++
Sbjct: 219 GPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVICS---KGADLSLRLVDGVTEC 275
Query: 427 EGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVV 486
GR+EV+ G WG IC D W + +A VAC+QLG A + S +
Sbjct: 276 SGRLEVRFQG----EWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRV--NASKGFGHIW 329
Query: 487 MSGVRCTGTELSLDQCAHH--GTHITCKRTGTRFTAGVICSETASDLLL 533
+ V C G E ++ QC HH G H C AGV CS+ SDL L
Sbjct: 330 LDSVSCQGHEPAVWQCKHHEWGKHY-CNHNE---DAGVTCSD-GSDLEL 373
Score = 58.5 bits (140), Expect = 2e-08
Identities = 60/254 (23%), Positives = 100/254 (39%), Gaps = 40/254 (15%)
Query: 51 RKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLD 110
R+ GR+E+ G WGT+ + ++CR+LG + ++ + +W+D
Sbjct: 832 REACAGRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCADKGKINPASLDKAMSIPMWVD 891
Query: 111 NLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVR 170
N+ C ++ +C S W ++RL S+ I ++ ++++E
Sbjct: 892 NVQCPKGPDTLWQCPSSPW----------------EKRLASPSEETWITCDNKIRLQE-- 933
Query: 171 IRPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGF-PSEKRVNAAF 229
P GR VE+ W VCD W ++ VVC LG P+ K AF
Sbjct: 934 -GPTSCSGR---------VEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALK----AF 979
Query: 230 YRLLAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSC----VPGP 285
+ L+ V C G E+ L C R + C A V+C V
Sbjct: 980 KEAEFGQGTGPIWLNEVKCKGNESSLWDCPA---RRWGHSECGHKEDAAVNCTDISVQKT 1036
Query: 286 VYAASSGQKKQQQS 299
A++G+ +Q S
Sbjct: 1037 PQKATTGRSSRQSS 1050
>gi|4506143 neurotrypsin precursor [Homo sapiens]
Length = 875
Score = 211 bits (536), Expect = 3e-54
Identities = 136/405 (33%), Positives = 190/405 (46%), Gaps = 50/405 (12%)
Query: 45 RLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGT 104
RLAG +EGRVE+ AG+WGT+CDD + A ++CR+LG + H A +G G+
Sbjct: 281 RLAG-GSSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEGS 339
Query: 105 GRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHL 164
G + LD + C+G E S+ +C WG +C H EDAGV C
Sbjct: 340 GPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSC-------------------T 380
Query: 165 QVEEVRIRPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKR 224
+ + IR A G G EG +EV W VCD GW+ N++VVC LGF K+
Sbjct: 381 PLTDGVIRLAGGKGSH-----EGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKYGKQ 435
Query: 225 VNAAFYRLLAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPG 284
+A + + L V+C G E CS + +D C ++C PG
Sbjct: 436 ASANHF----EESTGPIWLDDVSCSGKETRFLQCSRRQWGRHD---CSHREDVSIACYPG 488
Query: 285 PVYAASSGQKKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVV 344
G + VRL G + EGRVEV WGT+CD W A+V+
Sbjct: 489 -----GEGHRLSLGFP------VRLMDGENKKEGRVEVFINGQWGTICDDGWTDKDAAVI 537
Query: 345 CRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGV 404
CR+LG+ A + A G+G G IH+ V+C+G E SL C ++I +C HS+DAGV
Sbjct: 538 CRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRHNCRHSEDAGV 597
Query: 405 RCNL------PYTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWG 443
C+ + E+ + G R H + + IGG LR G
Sbjct: 598 ICDYFGKKASGNSNKESLSSVCGLRLLHRRQKRI-IGGKNSLRGG 641
Score = 183 bits (465), Expect = 4e-46
Identities = 146/487 (29%), Positives = 197/487 (40%), Gaps = 76/487 (15%)
Query: 51 RKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTG----R 106
+ +EG VE+ +G WGT+C + A ++C +L G AK P +G
Sbjct: 176 KNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQL----QLGGKGIAKQTPFSGLGLIP 231
Query: 107 IWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQV 166
I+ N+ C G E+++ C W C A V C P F
Sbjct: 232 IYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFP------------- 278
Query: 167 EEVRIRPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVN 226
IR A G V EG VE+ W VCD W ++ V+C LG +
Sbjct: 279 ---IIRLAGG-----SSVHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSG---IA 327
Query: 227 AAFYRLLAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPV 286
A+++ L V C G E + C + ++ C A VSC
Sbjct: 328 KAWHQAYFGEGSGPVMLDEVRCTGNELSIEQCPKSSWGEHN---CGHKEDAGVSCT---- 380
Query: 287 YAASSGQKKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCR 346
P + +RL GG EGR+EV WGTVCD W VVCR
Sbjct: 381 --------------PLTDGVIRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTELNTYVVCR 426
Query: 347 ELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRC 406
+LGF ++A S + G I L +V CSG+E +C + DCSH +D + C
Sbjct: 427 QLGFKYGKQA-SANHFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSHREDVSIAC 485
Query: 407 NLPYTGAETR-------IRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVAC 459
Y G E +RL G ++ EGRVEV I G +WG IC D W +A V C
Sbjct: 486 ---YPGGEGHRLSLGFPVRLMDGENKKEGRVEVFING----QWGTICDDGWTDKDAAVIC 538
Query: 460 RQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHH--GTHITCKRTGTR 517
RQ LGY T + + + V+CTG E SL C G H C+ +
Sbjct: 539 RQ--LGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADCIKQDIGRH-NCRHSE-- 593
Query: 518 FTAGVIC 524
AGVIC
Sbjct: 594 -DAGVIC 599
Score = 138 bits (347), Expect = 2e-32
Identities = 86/224 (38%), Positives = 113/224 (50%), Gaps = 18/224 (8%)
Query: 307 VRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGM 366
VRL+GG + EG VEV + WGTVC WD ASV+C +L G A G G+
Sbjct: 170 VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLGL 229
Query: 367 GAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLSGGRSQH 426
I+ S VRC G E ++ C C A V C+ + IRL+GG S H
Sbjct: 230 IPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFPIIRLAGGSSVH 289
Query: 427 EGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETW---YWDSGNIT 483
EGRVE+ G +WG +C D W +A V CRQLGL G+ + W Y+ G+
Sbjct: 290 EGRVELYHAG----QWGTVCDDQWDDADAEVICRQLGLS----GIAKAWHQAYFGEGS-G 340
Query: 484 EVVMSGVRCTGTELSLDQC--AHHGTHITCKRTGTRFTAGVICS 525
V++ VRCTG ELS++QC + G H G + AGV C+
Sbjct: 341 PVMLDEVRCTGNELSIEQCPKSSWGEH----NCGHKEDAGVSCT 380
>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
Length = 1573
Score = 196 bits (498), Expect = 7e-50
Identities = 168/563 (29%), Positives = 216/563 (38%), Gaps = 137/563 (24%)
Query: 43 RFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGP 102
R RLA P GR+E+ G WGT+CDD + L+ A + CR+LG A A +G
Sbjct: 19 RLRLADGPHG-CAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGE 77
Query: 103 GTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNV----- 157
G G +WL L+C G E + C RGW C+H+EDAGV+C QR+ D +
Sbjct: 78 GAGPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVANSRDDSTSPLDG 137
Query: 158 -----IEVEHHLQVEEVRI----RPA----------------VGWGRRPLPVT------- 185
+ +E EE + RPA R PL T
Sbjct: 138 APWPGLLLELSPSTEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAPLLTTGAPRQER 197
Query: 186 ----------EGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQ 235
G +EV W VCD GW ++ V C LG LA
Sbjct: 198 LRLVSGPHRCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGG----------ALAA 247
Query: 236 RQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKK 295
FG G V D C GG A+ C P ++ +
Sbjct: 248 PGGARFG-PGAGPVWM---------------DDVGCGGGEQALRDCPRSPWGRSNCDHSE 291
Query: 296 QQQSKPQGEA-RVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAR 354
G A R+RL G H GR+EV WG+VCD WDL A+V CRELG G A
Sbjct: 292 DAGLVCTGPAPRLRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVACRELGCGGAL 351
Query: 355 EALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCN------- 407
A GA G+G G I L ++RC G E +L CP + DC H +DAG C+
Sbjct: 352 AAPGGAFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGAVCDGMPLGYV 411
Query: 408 ---LPYTGAETRIRLSGGR------SQHEGRVEVQ--------IGGPGP----------- 439
P + R + R SQ G V + PGP
Sbjct: 412 PPTAPTDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAGSPQLRLVA 471
Query: 440 --------------LRWGLICGDDWGTLEAMVACRQLGLGYANHGLQE------TWYWDS 479
RWG +C D W ++ V CR+LG G G Q+ + W +
Sbjct: 472 GPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCG----GPQQPDPAAGRFGWGA 527
Query: 480 GNITEVVMSGVRCTGTELSLDQC 502
G I + V C GTE SL C
Sbjct: 528 GPIW---LDDVGCVGTEASLSDC 547
Score = 173 bits (439), Expect = 5e-43
Identities = 124/405 (30%), Positives = 165/405 (40%), Gaps = 69/405 (17%)
Query: 43 RFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGP 102
R RL P + GR+E+ G WGT+CDD + L+ A + CRELG A A++GP
Sbjct: 197 RLRLVSGPHR-CAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGGARFGP 255
Query: 103 GTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEH 162
G G +W+D++ C G EQ++ +C WG S+C H EDAG++C
Sbjct: 256 GAGPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTG---------------- 299
Query: 163 HLQVEEVRIRPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSE 222
R+R A G G +EV W VCD W ++ V C LG
Sbjct: 300 ----PAPRLRLADG-----PHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVACRELGCGGA 350
Query: 223 KRV-NAAFYRLLAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSC 281
AF+ L + C G E L C + +D G AV
Sbjct: 351 LAAPGGAFF----GEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAG-AVCDG 405
Query: 282 VP---------------GPVYAASSGQKKQQQSKP---------------------QGEA 305
+P P AAS P G
Sbjct: 406 MPLGYVPPTAPTDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAGSP 465
Query: 306 RVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGA-RMGQ 364
++RL G GR+EV WGTVCD WD+ ++VVCRELG G ++ A R G
Sbjct: 466 QLRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRFGW 525
Query: 365 GMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLP 409
G G I L +V C G E SL CP +C+H++D GV C P
Sbjct: 526 GAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCTGP 570
Score = 157 bits (398), Expect = 3e-38
Identities = 121/394 (30%), Positives = 162/394 (41%), Gaps = 77/394 (19%)
Query: 187 GLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRV-NAAFYRLLAQRQQHSFGLHG 245
G +EV W VCD GW ++ V C LG AF+ A L
Sbjct: 31 GRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGEGAG----PVWLSE 86
Query: 246 VACVGTEAHLSLCSLEFYRANDTAR-------CPG---------------GGP------- 276
+AC G E L LC ++A+ + C G G P
Sbjct: 87 LACRGNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVANSRDDSTSPLDGAPWPGLLLE 146
Query: 277 -------AVVSCVPGPVYAASSGQKKQQQSKPQGEA--------------RVRLKGGAHP 315
+V+ P P + +K+ Q ++ R+RL G H
Sbjct: 147 LSPSTEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAPLLTTGAPRQERLRLVSGPHR 206
Query: 316 GEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVR 375
GR+EV WGTVCD WDL A+V CRELG G A A GAR G G G + + +V
Sbjct: 207 CAGRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGGARFGPGAGPVWMDDVG 266
Query: 376 CSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLSGGRSQHEGRVEVQIG 435
C G E +L CP +C HS+DAG+ C TG R+RL+ G GR+EV G
Sbjct: 267 CGGGEQALRDCPRSPWGRSNCDHSEDAGLVC----TGPAPRLRLADGPHGCAGRLEVWHG 322
Query: 436 GPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGT 495
G RWG +C D W +A VACR+LG G A ++ + +++ +RC G
Sbjct: 323 G----RWGSVCDDAWDLRDAAVACRELGCGGALAAPGGAFFGEGSG--PIILDDLRCRGN 376
Query: 496 ELSLDQC-----AHHGTHITCKRTGTRFTAGVIC 524
E +L C H H R AG +C
Sbjct: 377 ETALRFCPARPWGQHDCH-------HREDAGAVC 403
Score = 109 bits (273), Expect = 8e-24
Identities = 91/289 (31%), Positives = 117/289 (40%), Gaps = 61/289 (21%)
Query: 10 SPWGLLLC-------LLCSSCLGSPSPSTGPEKKAGSQGLRFRLAGFPRKPYEGRVEIQR 62
SPWG C L+C+ P+P R RLA P GR+E+
Sbjct: 280 SPWGRSNCDHSEDAGLVCTG----PAP-------------RLRLADGPHG-CAGRLEVWH 321
Query: 63 AGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVT 122
G WG++CDD + L+ A + CRELG A A +G G+G I LD+L C G E ++
Sbjct: 322 GGRWGSVCDDAWDLRDAAVACRELGCGGALAAPGGAFFGEGSGPIILDDLRCRGNETALR 381
Query: 123 ECASRGWGNSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRP-------AV 175
C +R WG DC H EDAG +C L G+ ++ E RP A
Sbjct: 382 FCPARPWGQHDCHHREDAGAVCDGMPL-GYVPPTAPTDSNNSTPREAASRPPSTMTSQAP 440
Query: 176 GW-GRRPLPVT-------------------------EGLVEVRLPDGWSQVCDKGWSAHN 209
G G P P + G +EV W VCD W +
Sbjct: 441 GTAGVSPPPASPTVLWEPGPEAGSPQLRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRD 500
Query: 210 SHVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFGLHGVACVGTEAHLSLC 258
S VVC LG ++ + A R L V CVGTEA LS C
Sbjct: 501 SAVVCRELGCGGPQQPDPAAGRF--GWGAGPIWLDDVGCVGTEASLSDC 547
Score = 109 bits (272), Expect = 1e-23
Identities = 51/119 (42%), Positives = 72/119 (60%), Gaps = 3/119 (2%)
Query: 26 SPSPSTGPEKKAGSQGLRFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRE 85
+PSPS ++G R RLA P + GR+E+ AG WGT+CDD++ L+ A + C E
Sbjct: 756 APSPSVSTTGESGL--FRVRLADGPNR-CAGRLEVWHAGRWGTVCDDNWDLRDATVACWE 812
Query: 86 LGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVIC 144
LG + YGPGTG IWLD++ C G+E S+++C S WG +C H+ED G+ C
Sbjct: 813 LGCGKVRPRVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTC 871
Score = 102 bits (253), Expect = 2e-21
Identities = 51/105 (48%), Positives = 60/105 (57%)
Query: 302 QGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGAR 361
Q R+RL G H GR+EV WGTVCD WDL A+V CR+LG G A A GA
Sbjct: 15 QAVERLRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAF 74
Query: 362 MGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRC 406
G+G G + LSE+ C G E L C H+ A CSH +DAGV C
Sbjct: 75 FGEGAGPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVC 119
Score = 92.0 bits (227), Expect = 2e-18
Identities = 48/120 (40%), Positives = 70/120 (58%), Gaps = 4/120 (3%)
Query: 26 SPSPSTGPEKKAGSQGLRFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRE 85
SP+ P +AGS LR L P K GR+E+ WGT+CDD + ++ + ++CRE
Sbjct: 451 SPTVLWEPGPEAGSPQLR--LVAGPSK-CSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRE 507
Query: 86 LGFTEATGWTHSA-KYGPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVIC 144
LG +A ++G G G IWLD++ C GTE S+++C + WG +C H+ED GV C
Sbjct: 508 LGCGGPQQPDPAAGRFGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTC 567
Score = 90.1 bits (222), Expect = 7e-18
Identities = 45/104 (43%), Positives = 54/104 (51%)
Query: 303 GEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARM 362
G RVRL G + GR+EV A WGTVCD WDL A+V C ELG G R +
Sbjct: 768 GLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRVGKTHY 827
Query: 363 GQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRC 406
G G G I L ++ C G E SL CP +C H +D G+ C
Sbjct: 828 GPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHEEDVGLTC 871
Score = 60.5 bits (145), Expect = 6e-09
Identities = 42/115 (36%), Positives = 54/115 (46%), Gaps = 12/115 (10%)
Query: 413 AETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQ 472
A R+RL+ G GR+EV GG RWG +C D W +A VACRQLG G A
Sbjct: 16 AVERLRLADGPHGCAGRLEVWHGG----RWGTVCDDGWDLRDAAVACRQLGCGGALAAPG 71
Query: 473 ETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHG--THITCKRTGTRFTAGVICS 525
++ + V +S + C G E L C H G HI AGV+C+
Sbjct: 72 GAFFGEGAG--PVWLSELACRGNEGQLGLCHHRGWKAHICSHEE----DAGVVCA 120
Score = 54.3 bits (129), Expect = 4e-07
Identities = 30/87 (34%), Positives = 45/87 (51%), Gaps = 6/87 (6%)
Query: 416 RIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETW 475
R+RL+ G ++ GR+EV G RWG +C D+W +A VAC +LG G + +T
Sbjct: 771 RVRLADGPNRCAGRLEVWHAG----RWGTVCDDNWDLRDATVACWELGCGKVRPRVGKTH 826
Query: 476 YWDSGNITEVVMSGVRCTGTELSLDQC 502
Y + + + C G+E SL C
Sbjct: 827 Y--GPGTGPIWLDDMGCKGSEASLSDC 851
Score = 32.7 bits (73), Expect = 1.3
Identities = 27/88 (30%), Positives = 32/88 (36%), Gaps = 20/88 (22%)
Query: 187 GLVEVRLPDG---------------WSQVCDKGWSAHNSHVVCGMLGFPSEK-RVNAAFY 230
GL VRL DG W VCD W ++ V C LG + RV Y
Sbjct: 768 GLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLRDATVACWELGCGKVRPRVGKTHY 827
Query: 231 RLLAQRQQHSFGLHGVACVGTEAHLSLC 258
L + C G+EA LS C
Sbjct: 828 ----GPGTGPIWLDDMGCKGSEASLSDC 851
>gi|5174411 CD5 molecule-like [Homo sapiens]
Length = 347
Score = 169 bits (427), Expect = 1e-41
Identities = 129/408 (31%), Positives = 185/408 (45%), Gaps = 78/408 (19%)
Query: 14 LLLCLLCSSCLGSPSPSTGPEKKAGSQGLRFRLAGFPRKPYEGRVEIQRAGEWGTICDDD 73
LL L+ + C T P A G+R + G R EGRVE+++ G+WGT+CDD
Sbjct: 3 LLFSLILAIC-------TRPGFLASPSGVRL-VGGLHR--CEGRVEVEQKGQWGTVCDDG 52
Query: 74 FTLQAAHILCRELGFTEATGWTHSAKYGPGTGR---IWLDNLSCSGTEQSVTECASRGWG 130
+ ++ +LCRELG A+G Y P + + + ++SC+GTE ++ +C
Sbjct: 53 WDIKDVAVLCRELGCGAASGTPSGILYEPPAEKEQKVLIQSVSCTGTEDTLAQCEQEEV- 111
Query: 131 NSDCTHDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAVGWGRRPLPVTEGLVE 190
DC+HDEDAG C++ P S S V E +R A G G +G VE
Sbjct: 112 -YDCSHDEDAGASCEN---PESSFSPVPE----------GVRLADGPGH-----CKGRVE 152
Query: 191 VRLPDGWSQVCDKGWSAHNSHVVCGMLGFP----SEKRVNAAFYRLLAQRQQHSFG---- 242
V+ + W VC GWS + VVC LG ++KR N +H++G
Sbjct: 153 VKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLTQKRCN-----------KHAYGRKPI 201
Query: 243 -LHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKP 301
L ++C G EA L C GP + + +
Sbjct: 202 WLSQMSCSGREATLQ-----------------------DCPSGPWGKNTCNHDEDTWVEC 238
Query: 302 QGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGAR 361
+ +RL GG + GR+EVL WG+VCD W VVC++LG G + R
Sbjct: 239 EDPFDLRLVGGDNLCSGRLEVLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSLSPSFRDR 298
Query: 362 M--GQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCN 407
G G+G I L VRCSG+E SL +C H+ DC+H +D V C+
Sbjct: 299 KCYGPGVGRIWLDNVRCSGEEQSLEQCQHRFWGFHDCTHQEDVAVICS 346
Score = 152 bits (384), Expect = 1e-36
Identities = 109/324 (33%), Positives = 150/324 (46%), Gaps = 35/324 (10%)
Query: 186 EGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRV-NAAFYRLLAQRQQHSFGLH 244
EG VEV W VCD GW + V+C LG + + Y A+++Q +
Sbjct: 34 EGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILYEPPAEKEQKVL-IQ 92
Query: 245 GVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKPQGE 304
V+C GTE L+ C E + C A SC + + P E
Sbjct: 93 SVSCTGTEDTLAQCEQE-----EVYDCSHDEDAGASC-----------ENPESSFSPVPE 136
Query: 305 ARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQ 364
VRL G +GRVEV + W TVC W L AA VVCR+LG G R L+ R +
Sbjct: 137 G-VRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCG--RAVLTQKRCNK 193
Query: 365 ---GMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYTGAETRIRLSG 421
G I LS++ CSG+E +L CP C+H +D V C P+ +RL G
Sbjct: 194 HAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVECEDPFD-----LRLVG 248
Query: 422 GRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYA-NHGLQETWYWDSG 480
G + GR+EV G WG +C D+WG E V C+QLG G + + ++ + G
Sbjct: 249 GDNLCSGRLEVLHKGV----WGSVCDDNWGEKEDQVVCKQLGCGKSLSPSFRDRKCYGPG 304
Query: 481 NITEVVMSGVRCTGTELSLDQCAH 504
+ + + VRC+G E SL+QC H
Sbjct: 305 -VGRIWLDNVRCSGEEQSLEQCQH 327
Score = 113 bits (283), Expect = 6e-25
Identities = 72/202 (35%), Positives = 101/202 (50%), Gaps = 13/202 (6%)
Query: 307 VRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARM---G 363
VRL GG H EGRVEV + WGTVCD WD+ +V+CRELG G+A SG
Sbjct: 24 VRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGILYEPPA 83
Query: 364 QGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLP---YTGAETRIRLS 420
+ + + V C+G E +L +C + + DCSH +DAG C P ++ +RL+
Sbjct: 84 EKEQKVLIQSVSCTGTEDTLAQCEQEEV--YDCSHDEDAGASCENPESSFSPVPEGVRLA 141
Query: 421 GGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSG 480
G +GRVEV+ +W +C W A V CRQLG G A Q+ +
Sbjct: 142 DGPGHCKGRVEVKHQN----QWYTVCQTGWSLRAAKVVCRQLGCGRAVL-TQKRCNKHAY 196
Query: 481 NITEVVMSGVRCTGTELSLDQC 502
+ +S + C+G E +L C
Sbjct: 197 GRKPIWLSQMSCSGREATLQDC 218
Score = 59.7 bits (143), Expect = 1e-08
Identities = 36/99 (36%), Positives = 51/99 (51%), Gaps = 6/99 (6%)
Query: 406 CNLP-YTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGL 464
C P + + + +RL GG + EGRVEV+ G +WG +C D W + V CR+LG
Sbjct: 12 CTRPGFLASPSGVRLVGGLHRCEGRVEVEQKG----QWGTVCDDGWDIKDVAVLCRELGC 67
Query: 465 GYANHGLQETWYWDSGNITE-VVMSGVRCTGTELSLDQC 502
G A+ Y + V++ V CTGTE +L QC
Sbjct: 68 GAASGTPSGILYEPPAEKEQKVLIQSVSCTGTEDTLAQC 106
>gi|239752563 PREDICTED: hypothetical protein [Homo sapiens]
Length = 343
Score = 160 bits (404), Expect = 5e-39
Identities = 107/275 (38%), Positives = 135/275 (49%), Gaps = 34/275 (12%)
Query: 307 VRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGM 366
+RL G +GRVEVL +WGTVCD WD + A+VVCR+LG G A A AR GQG
Sbjct: 18 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGS 77
Query: 367 GAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCN--LPYTGAETR-------- 416
G I L +VRCSG E LW CPH + +C HS+DAGV C+ P T R
Sbjct: 78 GPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRSWPSRFLC 137
Query: 417 ----------IRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGY 466
+RL G + +GRVEV G WG +C D W T +A V CRQLG G+
Sbjct: 138 SPIGPESSLALRLVNGGDRCQGRVEVLYRG----SWGTVCDDSWDTNDANVVCRQLGCGW 193
Query: 467 ANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAGVICSE 526
A + +V+ VRC+G E L C ++G G AGVICS
Sbjct: 194 ATSAPGNARFGQGSG--PIVLDDVRCSGHESYLWSCPNNGW--LSHNCGHHEDAGVICS- 248
Query: 527 TASDLLLHSALVQE---TAYIEDRPLHMLYCAAEE 558
S + QE A +D PL + CAA++
Sbjct: 249 -GSWAVAGPRRPQEMPGLARAQD-PLFWMMCAAQD 281
Score = 134 bits (337), Expect = 3e-31
Identities = 83/229 (36%), Positives = 111/229 (48%), Gaps = 15/229 (6%)
Query: 186 EGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLG--FPSEKRVNAAFYRLLAQRQQHSFGL 243
+G VEV W VCD W ++++VVC LG + NA F + L
Sbjct: 28 QGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARF-----GQGSGPIVL 82
Query: 244 HGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSK--- 300
V C G E++L C + +++ C A V C GP + +
Sbjct: 83 DDVRCSGNESYLWSCPHNGWLSHN---CGHSEDAGVICSGGPPRTPIRPRSWPSRFLCSP 139
Query: 301 --PQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALS 358
P+ +RL G +GRVEVL +WGTVCD WD + A+VVCR+LG G A A
Sbjct: 140 IGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPG 199
Query: 359 GARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCN 407
AR GQG G I L +VRCSG E LW CP+ + +C H +DAGV C+
Sbjct: 200 NARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICS 248
Score = 107 bits (267), Expect = 4e-23
Identities = 71/215 (33%), Positives = 102/215 (47%), Gaps = 26/215 (12%)
Query: 55 EGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSC 114
+GRVE+ G WGT+CDD + A+++CR+LG A +A++G G+G I LD++ C
Sbjct: 28 QGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRC 87
Query: 115 SGTEQSVTECASRGWGNSDCTHDEDAGVIC---------KDQRLPGFSDSNVIEVEHHLQ 165
SG E + C GW + +C H EDAGVIC + + P + I E L
Sbjct: 88 SGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRSWPSRFLCSPIGPESSLA 147
Query: 166 VEEVRIRPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGML--GFPSEK 223
+ V G R +G VEV W VCD W ++++VVC L G+ +
Sbjct: 148 LR------LVNGGDR----CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSA 197
Query: 224 RVNAAFYRLLAQRQQHSFGLHGVACVGTEAHLSLC 258
NA F + L V C G E++L C
Sbjct: 198 PGNARF-----GQGSGPIVLDDVRCSGHESYLWSC 227
Score = 94.4 bits (233), Expect = 4e-19
Identities = 44/109 (40%), Positives = 65/109 (59%), Gaps = 10/109 (9%)
Query: 55 EGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSC 114
+GRVE+ G WGT+CDD + A+++CR+LG AT +A++G G+G I LD++ C
Sbjct: 158 QGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRC 217
Query: 115 SGTEQSVTECASRGWGNSDCTHDEDAGVIC----------KDQRLPGFS 153
SG E + C + GW + +C H EDAGVIC + Q +PG +
Sbjct: 218 SGHESYLWSCPNNGWLSHNCGHHEDAGVICSGSWAVAGPRRPQEMPGLA 266
>gi|194018748 CD6 molecule [Homo sapiens]
Length = 668
Score = 135 bits (340), Expect = 1e-31
Identities = 109/360 (30%), Positives = 147/360 (40%), Gaps = 63/360 (17%)
Query: 187 GLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFGLHGV 246
G VEVRL W C W + + VC LG + + + G V
Sbjct: 56 GTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSV 115
Query: 247 ACVGTEAHLS--LCSLEFYRANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKPQGE 304
A T A LCS +R + +A S ++ + + +
Sbjct: 116 AANATLAGAPALLCSGAEWRLCEVVE----------------HACRSDGRRARVTCAENR 159
Query: 305 ARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQ 364
A +RL G GRVE+L+ WG+VCD WDL A VVCR+LG G A +AL G
Sbjct: 160 A-LRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTP 218
Query: 365 GMGAIHLSEVRCSGQELSLWKCPHKNITAED-CSHSQDAGVRCNLPYTGAETRIRLSGGR 423
G G IH +V CSG E LW CP + + C H +DAG C+ RL+GG
Sbjct: 219 GRGPIHRDQVNCSGAEAYLWDCP--GLPGQHYCGHKEDAGAVCS-----EHQSWRLTGGA 271
Query: 424 SQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYA-------NHGLQETWY 476
+ EG+VEV G W +C +W EA V C+ LG G A H L Y
Sbjct: 272 DRCEGQVEVHFRGV----WNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSLSGRMY 327
Query: 477 WDSGNITEVVMSGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAGVICSETASDLLLHSA 536
+ C G EL+L C+ RF +CS++ + +L SA
Sbjct: 328 YS-------------CNGEELTLSNCS------------WRFNNSNLCSQSLAARVLCSA 362
Score = 98.6 bits (244), Expect = 2e-20
Identities = 67/214 (31%), Positives = 90/214 (42%), Gaps = 40/214 (18%)
Query: 56 GRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCS 115
GRVE+ GEWG++CDD + L+ AH++CR+LG A + PG G I D ++CS
Sbjct: 172 GRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCS 231
Query: 116 GTEQSVTECASRGWGNSDCTHDEDAGVICKDQ---RLPGFSDSNVIEVEHHLQVEEVRIR 172
G E + +C G C H EDAG +C + RL G +D
Sbjct: 232 GAEAYLWDCPGLP-GQHYCGHKEDAGAVCSEHQSWRLTGGADR----------------- 273
Query: 173 PAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRL 232
EG VEV W+ VCD W + V+C LG +
Sbjct: 274 ------------CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHS 321
Query: 233 LAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRAN 266
L+ R +S C G E LS CS F +N
Sbjct: 322 LSGRMYYS-------CNGEELTLSNCSWRFNNSN 348
Score = 79.3 bits (194), Expect = 1e-14
Identities = 75/264 (28%), Positives = 98/264 (37%), Gaps = 37/264 (14%)
Query: 283 PGPVYAASSGQKKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAAS 342
P P ++ + + +P VRL G+ G VEV ++W C WD AA
Sbjct: 21 PAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAE 80
Query: 343 VVCRELGFGSAR---------------EALSGARMGQGMGAIHLSEVRCSGQELSLWKCP 387
VCR LG G A A + + CSG E L +
Sbjct: 81 AVCRALGCGGAEAASQLAPPTPELPPPPAAGNTSVAANATLAGAPALLCSGAEWRLCE-- 138
Query: 388 HKNITAEDC-SHSQDAGVRCNLPYTGAETR-IRLSGGRSQHEGRVEVQIGGPGPLRWGLI 445
+ C S + A V C AE R +RL G GRVE+ G WG +
Sbjct: 139 ---VVEHACRSDGRRARVTC------AENRALRLVDGGGACAGRVEMLEHG----EWGSV 185
Query: 446 CGDDWGTLEAMVACRQLGLGYANHGLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHH 505
C D W +A V CRQLG G+A L + + V C+G E L C
Sbjct: 186 CDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRG--PIHRDQVNCSGAEAYLWDCPGL 243
Query: 506 GTHITCKRTGTRFTAGVICSETAS 529
C G + AG +CSE S
Sbjct: 244 PGQHYC---GHKEDAGAVCSEHQS 264
Score = 52.0 bits (123), Expect = 2e-06
Identities = 48/161 (29%), Positives = 75/161 (46%), Gaps = 21/161 (13%)
Query: 23 CLGSPSPS-TGPEKKAG---SQGLRFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQA 78
C G P G ++ AG S+ +RL G + EG+VE+ G W T+CD ++
Sbjct: 240 CPGLPGQHYCGHKEDAGAVCSEHQSWRLTGGADR-CEGQVEVHFRGVWNTVCDSEWYPSE 298
Query: 79 AHILCRELGFTEAT----GWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDC 134
A +LC+ LG A G HS +GR++ SC+G E +++ C+ R ++ C
Sbjct: 299 AKVLCQSLGCGTAVERPKGLPHSL-----SGRMY---YSCNGEELTLSNCSWRFNNSNLC 350
Query: 135 THDEDAGVICKDQRLPGFSDSNVIEVEHHLQVEEVRIRPAV 175
+ A V+C R S N+ E V+ V I +V
Sbjct: 351 SQSLAARVLCSASR----SLHNLSTPEVPASVQTVTIESSV 387
>gi|20357512 macrophage scavenger receptor 1 isoform type 1 [Homo
sapiens]
Length = 451
Score = 109 bits (273), Expect = 8e-24
Identities = 57/132 (43%), Positives = 75/132 (56%), Gaps = 8/132 (6%)
Query: 285 PVYAA---SSGQKKQQQSKPQGEA-----RVRLKGGAHPGEGRVEVLKASTWGTVCDRKW 336
P YA +SG K Q+ K G +VRL GG+ P EGRVE+L + WGT+CD +W
Sbjct: 320 PGYAGRPGNSGPKGQKGEKGSGNTLTPFTKVRLVGGSGPHEGRVEILHSGQWGTICDDRW 379
Query: 337 DLHAASVVCRELGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDC 396
++ VVCR LG+ + A GQG G I L+EV C G+E S+ +C + C
Sbjct: 380 EVRVGQVVCRSLGYPGVQAVHKAAHFGQGTGPIWLNEVFCFGRESSIEECKIRQWGTRAC 439
Query: 397 SHSQDAGVRCNL 408
SHS+DAGV C L
Sbjct: 440 SHSEDAGVTCTL 451
Score = 108 bits (269), Expect = 2e-23
Identities = 50/122 (40%), Positives = 71/122 (58%), Gaps = 7/122 (5%)
Query: 30 STGPEKKAGSQGLRFRLAGFPRK-------PYEGRVEIQRAGEWGTICDDDFTLQAAHIL 82
++GP+ + G +G L F + P+EGRVEI +G+WGTICDD + ++ ++
Sbjct: 328 NSGPKGQKGEKGSGNTLTPFTKVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVV 387
Query: 83 CRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGV 142
CR LG+ +A +G GTG IWL+ + C G E S+ EC R WG C+H EDAGV
Sbjct: 388 CRSLGYPGVQAVHKAAHFGQGTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGV 447
Query: 143 IC 144
C
Sbjct: 448 TC 449
Score = 53.1 bits (126), Expect = 9e-07
Identities = 37/116 (31%), Positives = 54/116 (46%), Gaps = 18/116 (15%)
Query: 415 TRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQET 474
T++RL GG HEGRVE+ G +WG IC D W V CR LG + +
Sbjct: 348 TKVRLVGGSGPHEGRVEILHSG----QWGTICDDRWEVRVGQVVCRSLGYP-GVQAVHKA 402
Query: 475 WYWDSGNITEVVMSGVRCTGTELSLDQCAHHGTHITCKRTGTRF-----TAGVICS 525
++ G + ++ V C G E S+++C ++ GTR AGV C+
Sbjct: 403 AHFGQGT-GPIWLNEVFCFGRESSIEEC-------KIRQWGTRACSHSEDAGVTCT 450
Score = 42.7 bits (99), Expect = 0.001
Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 6/96 (6%)
Query: 186 EGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFGLHG 245
EG VE+ W +CD W VVC LG+P + V+ A + + L+
Sbjct: 360 EGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAH---FGQGTGPIWLNE 416
Query: 246 VACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSC 281
V C G E+ + C + R T C A V+C
Sbjct: 417 VFCFGRESSIEECKI---RQWGTRACSHSEDAGVTC 449
>gi|5803080 macrophage receptor with collagenous structure [Homo
sapiens]
Length = 520
Score = 101 bits (251), Expect = 3e-21
Identities = 46/113 (40%), Positives = 66/113 (58%), Gaps = 6/113 (5%)
Query: 32 GPEKKAGSQGLRFRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEA 91
G + + G + R+ G + GR E+ +G WGTICDD++ A + CR LG+++
Sbjct: 412 GEKGERGENSVSVRIVGSSNR---GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKG 468
Query: 92 TGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVIC 144
K G GTG+IWLDN+ C GTE ++ C WG+ DC+H+EDAGV C
Sbjct: 469 RALY---KVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVEC 518
Score = 89.7 bits (221), Expect = 9e-18
Identities = 44/121 (36%), Positives = 64/121 (52%), Gaps = 5/121 (4%)
Query: 288 AASSGQKKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRE 347
+ G K ++ + + VR+ G ++ GR EV + TWGT+CD +W A V CR
Sbjct: 405 SGEQGVKGEKGERGENSVSVRIVGSSN--RGRAEVYYSGTWGTICDDEWQNSDAIVFCRM 462
Query: 348 LGFGSAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCN 407
LG+ R ++G G G I L V+C G E +LW C + DCSH +DAGV C+
Sbjct: 463 LGYSKGRALY---KVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECS 519
Query: 408 L 408
+
Sbjct: 520 V 520
Score = 48.5 bits (114), Expect = 2e-05
Identities = 35/110 (31%), Positives = 48/110 (43%), Gaps = 15/110 (13%)
Query: 417 IRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWY 476
+R+ G S + GR EV G WG IC D+W +A+V CR LG + Y
Sbjct: 424 VRIVG--SSNRGRAEVYYSGT----WGTICDDEWQNSDAIVFCRMLG-----YSKGRALY 472
Query: 477 WDSGNITEVVMSGVRCTGTELSLDQCAHHG-THITCKRTGTRFTAGVICS 525
++ + V+C GTE +L C + H C AGV CS
Sbjct: 473 KVGAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSH---EEDAGVECS 519
Score = 38.1 bits (87), Expect = 0.030
Identities = 29/95 (30%), Positives = 40/95 (42%), Gaps = 9/95 (9%)
Query: 187 GLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFGLHGV 246
G EV W +CD W ++ V C MLG+ + A Y++ A Q L V
Sbjct: 433 GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGR----ALYKVGAGTGQ--IWLDNV 486
Query: 247 ACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSC 281
C GTE+ L C+ + +D C A V C
Sbjct: 487 QCRGTESTLWSCTKNSWGHHD---CSHEEDAGVEC 518
>gi|5031863 galectin 3 binding protein [Homo sapiens]
Length = 585
Score = 100 bits (250), Expect = 4e-21
Identities = 51/114 (44%), Positives = 71/114 (62%), Gaps = 4/114 (3%)
Query: 37 AGSQGLR---FRLAGFPRKPYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATG 93
AG+QG+ RLA +GRVEI G+WGT+CD+ + L A ++CR LGF AT
Sbjct: 14 AGTQGVNDGDMRLAD-GGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQ 72
Query: 94 WTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVICKDQ 147
A +G G+G I LD + C+GTE S+ +C S GW S+C H+ DAGV+C ++
Sbjct: 73 ALGRAAFGQGSGPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCTNE 126
Score = 100 bits (250), Expect = 4e-21
Identities = 50/100 (50%), Positives = 59/100 (59%)
Query: 307 VRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGM 366
+RL G +GRVE+ WGTVCD WDL ASVVCR LGF +A +AL A GQG
Sbjct: 24 MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83
Query: 367 GAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRC 406
G I L EV+C+G E SL C +C H +DAGV C
Sbjct: 84 GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVC 123
Score = 56.6 bits (135), Expect = 8e-08
Identities = 38/115 (33%), Positives = 56/115 (48%), Gaps = 11/115 (9%)
Query: 417 IRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWY 476
+RL+ G + ++GRVE+ G +WG +C + W +A V CR LG A L +
Sbjct: 24 MRLADGGATNQGRVEIFYRG----QWGTVCDNLWDLTDASVVCRALGFENATQALGRAAF 79
Query: 477 WDSGNITEVVMSGVRCTGTELSLDQCAHHG-THITCKRTGTRFTAGVIC-SETAS 529
+++ V+CTGTE SL C G C+ AGV+C +ET S
Sbjct: 80 GQGSG--PIMLDEVQCTGTEASLADCKSLGWLKSNCRH---ERDAGVVCTNETRS 129
Score = 42.0 bits (97), Expect = 0.002
Identities = 28/82 (34%), Positives = 38/82 (46%), Gaps = 4/82 (4%)
Query: 186 EGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFGLHG 245
+G VE+ W VCD W ++ VVC LGF + A R + L
Sbjct: 34 QGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGF---ENATQALGRAAFGQGSGPIMLDE 90
Query: 246 VACVGTEAHLSLC-SLEFYRAN 266
V C GTEA L+ C SL + ++N
Sbjct: 91 VQCTGTEASLADCKSLGWLKSN 112
>gi|47271477 scavenger receptor class A, member 5 [Homo sapiens]
Length = 495
Score = 99.8 bits (247), Expect = 8e-21
Identities = 40/92 (43%), Positives = 60/92 (65%)
Query: 53 PYEGRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNL 112
P+EGRVE+ WGT+CDD + + ++CR LGF +A++G GTGRIW+D++
Sbjct: 401 PHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTARFGQGTGRIWMDDV 460
Query: 113 SCSGTEQSVTECASRGWGNSDCTHDEDAGVIC 144
+C GTE+++ C+ WG ++C H EDA V C
Sbjct: 461 ACKGTEETIFRCSFSKWGVTNCGHAEDASVTC 492
Score = 97.4 bits (241), Expect = 4e-20
Identities = 47/116 (40%), Positives = 60/116 (51%)
Query: 292 GQKKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFG 351
G + S + +RL G+ P EGRVEV WGTVCD WD VVCR LGF
Sbjct: 378 GDRAGDASGVEAPMMIRLVNGSGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFR 437
Query: 352 SAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCN 407
E AR GQG G I + +V C G E ++++C +C H++DA V CN
Sbjct: 438 GVEEVYRTARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493
Score = 51.2 bits (121), Expect = 3e-06
Identities = 37/115 (32%), Positives = 49/115 (42%), Gaps = 12/115 (10%)
Query: 413 AETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQ 472
A IRL G HEGRVEV RWG +C D W + V CR LG G++
Sbjct: 389 APMMIRLVNGSGPHEGRVEVY----HDRRWGTVCDDGWDKKDGDVVCRMLGF----RGVE 440
Query: 473 ETWYWD--SGNITEVVMSGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAGVICS 525
E + + M V C GTE ++ +C+ +T G A V C+
Sbjct: 441 EVYRTARFGQGTGRIWMDDVACKGTEETIFRCSFSKWGVT--NCGHAEDASVTCN 493
Score = 46.6 bits (109), Expect = 9e-05
Identities = 34/97 (35%), Positives = 40/97 (41%), Gaps = 8/97 (8%)
Query: 186 EGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQ-QHSFGLH 244
EG VEV W VCD GW + VVC MLGF + V YR Q +
Sbjct: 403 EGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEV----YRTARFGQGTGRIWMD 458
Query: 245 GVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSC 281
VAC GTE + CS + C A V+C
Sbjct: 459 DVACKGTEETIFRCSFSKW---GVTNCGHAEDASVTC 492
>gi|187936955 HHIP-like protein 1 isoform a [Homo sapiens]
Length = 782
Score = 99.8 bits (247), Expect = 8e-21
Identities = 55/150 (36%), Positives = 74/150 (49%), Gaps = 6/150 (4%)
Query: 264 RANDTARCPGGGPAVVSCVPGPVYAASSGQKKQQQSKPQ-----GEARVRLKGGAHPGEG 318
R TA P P P G+++ + + GE R+ G G G
Sbjct: 627 RGRPTAAPPAPTPRPARPTQQPGSRRGGGRRRGRLNSASRAFRDGEVRLVRPAGLSSGSG 686
Query: 319 RVEVLKASTWGTVCDRKWDLHAASVVCRELGFGSAREALSGARMGQGMG-AIHLSEVRCS 377
RVEV WGTVCD W++ A+VVCR+LGF A A+ A GQG I L +VRC+
Sbjct: 687 RVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPILLDDVRCA 746
Query: 378 GQELSLWKCPHKNITAEDCSHSQDAGVRCN 407
G E +L +C H + +C H +DAGV C+
Sbjct: 747 GWERNLLECQHNGVGTHNCEHDEDAGVVCS 776
Score = 91.7 bits (226), Expect = 2e-18
Identities = 41/93 (44%), Positives = 58/93 (62%), Gaps = 1/93 (1%)
Query: 56 GRVEIQRAGEWGTICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTG-RIWLDNLSC 114
GRVE+ G WGT+CDD + + A ++CR+LGF A A++G G I LD++ C
Sbjct: 686 GRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFGQGGSLPILLDDVRC 745
Query: 115 SGTEQSVTECASRGWGNSDCTHDEDAGVICKDQ 147
+G E+++ EC G G +C HDEDAGV+C Q
Sbjct: 746 AGWERNLLECQHNGVGTHNCEHDEDAGVVCSHQ 778
Score = 77.8 bits (190), Expect = 3e-14
Identities = 46/124 (37%), Positives = 63/124 (50%), Gaps = 11/124 (8%)
Query: 410 YTGAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANH 469
+ E R+ G S GRVEV +GG RWG +C D W A V CRQLG YA
Sbjct: 668 FRDGEVRLVRPAGLSSGSGRVEVFVGG----RWGTVCDDSWNISGAAVVCRQLGFAYAVR 723
Query: 470 GLQETWYWDSGNITEVVMSGVRCTGTELSLDQCAHH--GTHITCKRTGTRFTAGVICSET 527
++ + G++ +++ VRC G E +L +C H+ GTH C+ AGV+CS
Sbjct: 724 AVKRAEFGQGGSL-PILLDDVRCAGWERNLLECQHNGVGTH-NCEHDE---DAGVVCSHQ 778
Query: 528 ASDL 531
DL
Sbjct: 779 NPDL 782
Score = 37.7 bits (86), Expect = 0.040
Identities = 37/115 (32%), Positives = 43/115 (37%), Gaps = 12/115 (10%)
Query: 168 EVR-IRPAVGWGRRPLPVTEGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVN 226
EVR +RPA L G VEV + W VCD W+ + VVC LGF V
Sbjct: 672 EVRLVRPA------GLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGF--AYAVR 723
Query: 227 AAFYRLLAQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSC 281
A Q L V C G E +L C + T C A V C
Sbjct: 724 AVKRAEFGQGGSLPILLDDVRCAGWERNLLECQ---HNGVGTHNCEHDEDAGVVC 775
>gi|20357515 macrophage scavenger receptor 1 isoform type 3 [Homo
sapiens]
Length = 388
Score = 54.7 bits (130), Expect = 3e-07
Identities = 22/41 (53%), Positives = 26/41 (63%)
Query: 104 TGRIWLDNLSCSGTEQSVTECASRGWGNSDCTHDEDAGVIC 144
TG IWL+ + C G E S+ EC R WG C+H EDAGV C
Sbjct: 346 TGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTC 386
Score = 42.4 bits (98), Expect = 0.002
Identities = 20/42 (47%), Positives = 26/42 (61%)
Query: 367 GAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNL 408
G I L+EV C G+E S+ +C + CSHS+DAGV C L
Sbjct: 347 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCTL 388
>gi|166197668 CD5 molecule [Homo sapiens]
Length = 495
Score = 44.3 bits (103), Expect = 4e-04
Identities = 75/300 (25%), Positives = 111/300 (37%), Gaps = 36/300 (12%)
Query: 186 EGLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFGLHG 245
+G +EV L DGW VC + W + +R+N L
Sbjct: 45 QGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSS 104
Query: 246 VACVGTEAHLSLCSLEFYRANDTARCPGGGPAVVSCV-PGPVYAASSGQKKQQQSKPQGE 304
+ C G S CS + ND G ++C+ P ++ +P
Sbjct: 105 IICYGQLGSFSNCS---HSRNDMCHSLG-----LTCLEPQKTTPPTTRPPPTTTPEPTAP 156
Query: 305 ARVRL---KGGAHPGEGRVEVLKASTWGTVC----DRKWDLHAASVVCRELGFGSAREAL 357
R++L GG H G VE S GT+ D+ DL + +C L GS + L
Sbjct: 157 PRLQLVAQSGGQHCA-GVVEFYSGSLGGTISYEAQDKTQDLE--NFLCNNLQCGSFLKHL 213
Query: 358 SGARMGQGMGAIHLSEVRCSGQELSL-WKCPHKNITA-EDCSHS---QDAGVRCNLPYTG 412
G+ E R Q L + WK + + T+ E C Q +G L +G
Sbjct: 214 PETEAGRAQDP---GEPR-EHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSG 269
Query: 413 AETRI--RLSGGRSQHEGRVEVQIGGPGPLRWGLICGDD--WGTLEAMVACRQLGLGYAN 468
+ ++ RL GG S EG VEV+ G +W +C +L CR+ G N
Sbjct: 270 FQPKVQSRLVGGSSICEGTVEVRQGA----QWAALCDSSSARSSLRWEEVCREQQCGSVN 325
Score = 32.7 bits (73), Expect = 1.3
Identities = 30/108 (27%), Positives = 45/108 (41%), Gaps = 23/108 (21%)
Query: 302 QGEARVRLKGGAHPGEGRVEVLKASTWGTVCDR-------KWDLHAASVVCRELGFGSA- 353
Q + + RL GG+ EG VEV + + W +CD +W+ VCRE GS
Sbjct: 271 QPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWE-----EVCREQQCGSVN 325
Query: 354 --REALSGARMGQGMGAIHLSEVRCSGQELSLWK----CPHKNITAED 395
R +G +G+ H +C LW+ C +T +D
Sbjct: 326 SYRVLDAGDPTSRGLFCPHQKLSQCH----ELWERNSYCKKVFVTCQD 369
>gi|119392081 complement factor I preproprotein [Homo sapiens]
Length = 583
Score = 40.0 bits (92), Expect = 0.008
Identities = 26/88 (29%), Positives = 38/88 (43%), Gaps = 3/88 (3%)
Query: 302 QGEARVRLKGGAHPGEGRVEVLKASTWGT--VCDRKWDLHAASVVCRELGFGSAREALSG 359
+G+ V LK G EG VEV T +C W + A+V C +LGF +
Sbjct: 109 EGKFSVSLKHGNTDSEGIVEVKLVDQDKTMFICKSSWSMREANVACLDLGFQQGADTQRR 168
Query: 360 ARMGQ-GMGAIHLSEVRCSGQELSLWKC 386
++ + + V C G E SL +C
Sbjct: 169 FKLSDLSINSTECLHVHCRGLETSLAEC 196
Score = 37.7 bits (86), Expect = 0.040
Identities = 34/115 (29%), Positives = 46/115 (40%), Gaps = 9/115 (7%)
Query: 417 IRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGLQETWY 476
+ L G + EG VEV++ + IC W EA VAC LG Q +
Sbjct: 114 VSLKHGNTDSEGIVEVKLVDQDKTMF--ICKSSWSMREANVACLDLGF-QQGADTQRRFK 170
Query: 477 WDSGNITEVVMSGVRCTGTELSLDQCAHHGTHITCKRT-GTRFTAGVICSETASD 530
+I V C G E SL +C T +RT G + A V+C +D
Sbjct: 171 LSDLSINSTECLHVHCRGLETSLAECT-----FTKRRTMGYQDFADVVCYTQKAD 220
Score = 32.7 bits (73), Expect = 1.3
Identities = 24/77 (31%), Positives = 34/77 (44%), Gaps = 4/77 (5%)
Query: 185 TEGLVEVRLPDGWSQ--VCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYRLLAQRQQHSFG 242
+EG+VEV+L D +C WS ++V C LGF F L+ +S
Sbjct: 123 SEGIVEVKLVDQDKTMFICKSSWSMREANVACLDLGFQQGADTQRRF--KLSDLSINSTE 180
Query: 243 LHGVACVGTEAHLSLCS 259
V C G E L+ C+
Sbjct: 181 CLHVHCRGLETSLAECT 197
Score = 31.2 bits (69), Expect = 3.7
Identities = 25/104 (24%), Positives = 44/104 (42%), Gaps = 19/104 (18%)
Query: 55 EGRVEIQRAGEWGT--ICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNL 112
EG VE++ + T IC ++++ A++ C +LGF + R L +L
Sbjct: 124 EGIVEVKLVDQDKTMFICKSSWSMREANVACLDLGFQQGADTQR---------RFKLSDL 174
Query: 113 SCSGTEQSVTECASRGWGNSDCT--------HDEDAGVICKDQR 148
S + TE C ++CT + + A V+C Q+
Sbjct: 175 SINSTECLHVHCRGLETSLAECTFTKRRTMGYQDFADVVCYTQK 218
>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
sapiens]
Length = 454
Score = 36.2 bits (82), Expect = 0.12
Identities = 14/33 (42%), Positives = 21/33 (63%)
Query: 320 VEVLKASTWGTVCDRKWDLHAASVVCRELGFGS 352
++V A++W T+C W H A+V C +LGF S
Sbjct: 117 LQVFTAASWKTMCSDDWKGHYANVACAQLGFPS 149
Score = 34.7 bits (78), Expect = 0.34
Identities = 12/34 (35%), Positives = 18/34 (52%)
Query: 188 LVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPS 221
+++V W +C W H ++V C LGFPS
Sbjct: 116 VLQVFTAASWKTMCSDDWKGHYANVACAQLGFPS 149
Score = 32.7 bits (73), Expect = 1.3
Identities = 25/79 (31%), Positives = 31/79 (39%), Gaps = 14/79 (17%)
Query: 395 DCSHSQDAGVRCNLPYTGAETRIRLSGGRSQHEGRVE---VQIGGPGPL-------RWGL 444
DCS RC + E R G +G E V++GG + W
Sbjct: 72 DCSGKY----RCRSSFKCIELIARCDGVSDCKDGEDEYRCVRVGGQNAVLQVFTAASWKT 127
Query: 445 ICGDDWGTLEAMVACRQLG 463
+C DDW A VAC QLG
Sbjct: 128 MCSDDWKGHYANVACAQLG 146
Score = 31.2 bits (69), Expect = 3.7
Identities = 11/31 (35%), Positives = 19/31 (61%)
Query: 58 VEIQRAGEWGTICDDDFTLQAAHILCRELGF 88
+++ A W T+C DD+ A++ C +LGF
Sbjct: 117 LQVFTAASWKTMCSDDWKGHYANVACAQLGF 147
>gi|14602457 transmembrane protease, serine 3 isoform 3 [Homo
sapiens]
Length = 344
Score = 36.2 bits (82), Expect = 0.12
Identities = 14/33 (42%), Positives = 21/33 (63%)
Query: 320 VEVLKASTWGTVCDRKWDLHAASVVCRELGFGS 352
++V A++W T+C W H A+V C +LGF S
Sbjct: 117 LQVFTAASWKTMCSDDWKGHYANVACAQLGFPS 149
Score = 34.7 bits (78), Expect = 0.34
Identities = 12/34 (35%), Positives = 18/34 (52%)
Query: 188 LVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPS 221
+++V W +C W H ++V C LGFPS
Sbjct: 116 VLQVFTAASWKTMCSDDWKGHYANVACAQLGFPS 149
Score = 32.7 bits (73), Expect = 1.3
Identities = 25/79 (31%), Positives = 31/79 (39%), Gaps = 14/79 (17%)
Query: 395 DCSHSQDAGVRCNLPYTGAETRIRLSGGRSQHEGRVE---VQIGGPGPL-------RWGL 444
DCS RC + E R G +G E V++GG + W
Sbjct: 72 DCSGKY----RCRSSFKCIELIARCDGVSDCKDGEDEYRCVRVGGQNAVLQVFTAASWKT 127
Query: 445 ICGDDWGTLEAMVACRQLG 463
+C DDW A VAC QLG
Sbjct: 128 MCSDDWKGHYANVACAQLG 146
Score = 31.2 bits (69), Expect = 3.7
Identities = 11/31 (35%), Positives = 19/31 (61%)
Query: 58 VEIQRAGEWGTICDDDFTLQAAHILCRELGF 88
+++ A W T+C DD+ A++ C +LGF
Sbjct: 117 LQVFTAASWKTMCSDDWKGHYANVACAQLGF 147
>gi|239752583 PREDICTED: hypothetical protein XP_002348171 [Homo
sapiens]
Length = 146
Score = 34.7 bits (78), Expect = 0.34
Identities = 12/41 (29%), Positives = 21/41 (51%)
Query: 83 CRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTE 123
C GFT ++ W H + PG G +W+ ++ G+ S +
Sbjct: 41 CAASGFTFSSYWMHWVRQAPGKGLVWVSRINSDGSSTSYAD 81
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.452
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,958,781
Number of Sequences: 37866
Number of extensions: 1702229
Number of successful extensions: 4540
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 3796
Number of HSP's gapped (non-prelim): 215
length of query: 753
length of database: 18,247,518
effective HSP length: 110
effective length of query: 643
effective length of database: 14,082,258
effective search space: 9054891894
effective search space used: 9054891894
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.