Search of human proteins with 98986445

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|98986445 carcinoembryonic antigen-related cell adhesion
molecule 5 preproprotein [Homo sapiens]
         (702 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|98986445 carcinoembryonic antigen-related cell adhesion molec...  1437   0.0  
gi|68161541 carcinoembryonic antigen-related cell adhesion molec...   619   e-177
gi|19923195 carcinoembryonic antigen-related cell adhesion molec...   619   e-177
gi|40255013 carcinoembryonic antigen-related cell adhesion molec...   560   e-159
gi|21314600 carcinoembryonic antigen-related cell adhesion molec...   494   e-139
gi|164663836 pregnancy specific beta-1-glycoprotein 11 isoform 1...   350   3e-96
gi|194097369 pregnancy specific beta-1-glycoprotein 5 [Homo sapi...   349   4e-96
gi|194097367 pregnancy specific beta-1-glycoprotein 5 [Homo sapi...   349   4e-96
gi|156616282 pregnancy specific beta-1-glycoprotein 2 [Homo sapi...   348   1e-95
gi|47419900 pregnancy specific beta-1-glycoprotein 4 isoform 2 [...   344   1e-94
gi|5901930 carcinoembryonic antigen-related cell adhesion molecu...   324   2e-88
gi|194328710 pregnancy specific beta-1-glycoprotein 8 isoform b ...   295   1e-79
gi|51510887 pregnancy specific beta-1-glycoprotein 8 isoform a [...   295   1e-79
gi|157805480 pregnancy specific beta-1-glycoprotein 7 precursor ...   293   4e-79
gi|156616284 pregnancy specific beta-1-glycoprotein 9 [Homo sapi...   288   2e-77
gi|109240546 pregnancy specific beta-1-glycoprotein 3 [Homo sapi...   287   2e-77
gi|21361392 pregnancy specific beta-1-glycoprotein 1 [Homo sapiens]   286   5e-77
gi|42560235 pregnancy specific beta-1-glycoprotein 4 isoform 1 [...   286   5e-77
gi|4506175 pregnancy specific beta-1-glycoprotein 6 isoform a [H...   282   7e-76
gi|73661174 pregnancy specific beta-1-glycoprotein 6 isoform b [...   279   6e-75
gi|121114300 carcinoembryonic antigen-related cell adhesion mole...   250   4e-66
gi|194328712 pregnancy specific beta-1-glycoprotein 8 isoform c ...   226   7e-59
gi|52317156 carcinoembryonic antigen-related cell adhesion molec...   221   2e-57
gi|148612793 carcinoembryonic antigen-related cell adhesion mole...   219   7e-57
gi|164663826 pregnancy specific beta-1-glycoprotein 11 isoform 2...   211   2e-54
gi|164663824 pregnancy specific beta-1-glycoprotein 11 isoform 2...   211   2e-54
gi|156564378 carcinoembryonic antigen-related cell adhesion mole...   202   7e-52
gi|156564393 carcinoembryonic antigen-related cell adhesion mole...   202   7e-52
gi|85861202 carcinoembryonic antigen-related cell adhesion molec...   177   4e-44
gi|156564390 carcinoembryonic antigen-related cell adhesion mole...   156   5e-38

>gi|98986445 carcinoembryonic antigen-related cell adhesion molecule
           5 preproprotein [Homo sapiens]
          Length = 702

 Score = 1437 bits (3721), Expect = 0.0
 Identities = 702/702 (100%), Positives = 702/702 (100%)

Query: 1   MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ 60
           MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ
Sbjct: 1   MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ 60

Query: 61  HLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFY 120
           HLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFY
Sbjct: 61  HLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFY 120

Query: 121 TLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWV 180
           TLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWV
Sbjct: 121 TLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWV 180

Query: 181 NNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAP 240
           NNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAP
Sbjct: 181 NNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAP 240

Query: 241 TISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQ 300
           TISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQ
Sbjct: 241 TISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQ 300

Query: 301 AHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNN 360
           AHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNN
Sbjct: 301 AHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNN 360

Query: 361 QSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTI 420
           QSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTI
Sbjct: 361 QSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTI 420

Query: 421 SPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTCQAN 480
           SPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTCQAN
Sbjct: 421 SPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTCQAN 480

Query: 481 NSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQS 540
           NSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQS
Sbjct: 481 NSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQS 540

Query: 541 LPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISP 600
           LPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISP
Sbjct: 541 LPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISP 600

Query: 601 PDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQVLFIAKITPNNNGTYACFVSNL 660
           PDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQVLFIAKITPNNNGTYACFVSNL
Sbjct: 601 PDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQVLFIAKITPNNNGTYACFVSNL 660

Query: 661 ATGRNNSIVKSITVSASGTSPGLSAGATVGIMIGVLVGVALI 702
           ATGRNNSIVKSITVSASGTSPGLSAGATVGIMIGVLVGVALI
Sbjct: 661 ATGRNNSIVKSITVSASGTSPGLSAGATVGIMIGVLVGVALI 702


>gi|68161541 carcinoembryonic antigen-related cell adhesion molecule
           1 isoform 2 precursor [Homo sapiens]
          Length = 464

 Score =  619 bits (1596), Expect = e-177
 Identities = 309/423 (73%), Positives = 339/423 (80%), Gaps = 5/423 (1%)

Query: 5   SAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQHLFG 64
           SAP HR  +PWQ LLLTASLLTFWNPPTTA+LT ES PFNVAEGKEVLLLVHNLPQ LFG
Sbjct: 5   SAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQQLFG 64

Query: 65  YSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFYTLHV 124
           YSWYKGERVDGNRQI+GY IGTQQATPGPA SGRE IYPNASLLIQN+ QNDTGFYTL V
Sbjct: 65  YSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFYTLQV 124

Query: 125 IKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNNQS 184
           IKSDLVNEEATGQF VYPELPKPSISSNNS PVEDKDAVAFTCEPETQD TYLWW+NNQS
Sbjct: 125 IKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWINNQS 184

Query: 185 LPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTISP 244
           LPVSPRLQLSNGNRTLTL +VTRNDT  Y+CE QNPVSA RSD V LNV YGPD PTISP
Sbjct: 185 LPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTISP 244

Query: 245 LNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQAHNS 304
            +T YR G NL+LSC+AASNPPAQYSW +NGTFQQSTQELFIPNITVNNSGSYTC A+NS
Sbjct: 245 SDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCHANNS 304

Query: 305 DTGLNRTTVTTITVYAEPP---KPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQ 361
            TG NRTTV TI V    P   KP I ++ +    D+D+V LTC       +  W+  NQ
Sbjct: 305 VTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQ 364

Query: 362 SLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYG--PDDPT 419
           SLP S R++LS  N TL++  V R D G Y C + N +S + SDP++LNV Y   P +  
Sbjct: 365 SLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENG 424

Query: 420 ISP 422
           +SP
Sbjct: 425 LSP 427



 Score =  376 bits (966), Expect = e-104
 Identities = 192/311 (61%), Positives = 222/311 (71%), Gaps = 4/311 (1%)

Query: 284 LFIPNITVNNSGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVAL 343
           L I N+T N++G YT Q   SD  +N        VY E PKP I+SNNSNPVED+DAVA 
Sbjct: 107 LLIQNVTQNDTGFYTLQVIKSDL-VNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAF 165

Query: 344 TCEPEIQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDH 403
           TCEPE Q+TTYLWW+NNQSLPVSPRLQLSN NRTLTLLSVTRND GPYEC IQN +S + 
Sbjct: 166 TCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANR 225

Query: 404 SDPVILNVLYGPDDPTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELF 463
           SDPV LNV YGPD PTISPS TYYRPG NLSLSC+AASNPPAQYSWLI+G  QQ TQELF
Sbjct: 226 SDPVTLNVTYGPDTPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELF 285

Query: 464 ISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELP---KPSISSNNSKPVEDKDAVA 520
           I NIT  NSG YTC ANNS +G +RTTVKTI V+   P   KP I ++ +    DKD+V 
Sbjct: 286 IPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVN 345

Query: 521 FTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSAN 580
            TC       +  W+   QSLP S R++LS GN TL++  V R DA  Y C + N +S N
Sbjct: 346 LTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKN 405

Query: 581 RSDPVTLDVLY 591
           +SDP+ L+V Y
Sbjct: 406 QSDPIMLNVNY 416



 Score =  275 bits (703), Expect = 1e-73
 Identities = 139/214 (64%), Positives = 159/214 (74%), Gaps = 1/214 (0%)

Query: 462 LFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAF 521
           L I N+T+ ++G YT Q   S   +   T +   V  ELPKPSISSNNS PVEDKDAVAF
Sbjct: 107 LLIQNVTQNDTGFYTLQVIKSDLVNEEATGQ-FHVYPELPKPSISSNNSNPVEDKDAVAF 165

Query: 522 TCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANR 581
           TCEPE Q+TTYLWW+N QSLPVSPRLQLSNGNRTLTL +VTRND   Y C IQN VSANR
Sbjct: 166 TCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANR 225

Query: 582 SDPVTLDVLYGPDTPIISPPDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQVLF 641
           SDPVTL+V YGPDTP ISP D+ Y  GANL+LSC++ASNP  QYSW ING  QQ TQ LF
Sbjct: 226 SDPVTLNVTYGPDTPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELF 285

Query: 642 IAKITPNNNGTYACFVSNLATGRNNSIVKSITVS 675
           I  IT NN+G+Y C  +N  TG N + VK+I V+
Sbjct: 286 IPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVT 319



 Score = 69.7 bits (169), Expect = 9e-12
 Identities = 87/358 (24%), Positives = 152/358 (42%), Gaps = 47/358 (13%)

Query: 375 NRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTISPSYTYYRPGVN-- 432
           N +L + +VT+ND G Y   +     V+       +V   P+ P  S S     P  +  
Sbjct: 104 NASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVY--PELPKPSISSNNSNPVEDKD 161

Query: 433 -LSLSCHAASNPPAQYSWLIDGNIQQHTQELFISN---------ITEKNSGLYTCQANNS 482
            ++ +C   +     Y W I+      +  L +SN         +T  ++G Y C+  N 
Sbjct: 162 AVAFTCEPETQDTT-YLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNP 220

Query: 483 ASGHSRTTVK-TITVSAELPKPSISSNNSKPVEDKDAVAFTCE-PEAQNTTYLWWVNGQS 540
            S +    V   +T   + P  S S    +P  +     +    P AQ   Y W +NG  
Sbjct: 221 VSANRSDPVTLNVTYGPDTPTISPSDTYYRPGANLSLSCYAASNPPAQ---YSWLINGT- 276

Query: 541 LPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSA-NRSDPVTLDVLYGPDTPIIS 599
                        + L + N+T N++ +Y C   NSV+  NR+   T+ V     +P+++
Sbjct: 277 --------FQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVT--ELSPVVA 326

Query: 600 PPD----SSYLSGA--NLNLSCHSASNP-SPQYSWRINGIPQ-------QHTQVLFIAKI 645
            P      + ++G   ++NL+C +     S ++ ++   +P        Q    L I  +
Sbjct: 327 KPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPV 386

Query: 646 TPNNNGTYACFVSN-LATGRNNSIVKSITVSASGTSPGLSAGATVGIMIGVLVGVALI 702
              + GTY C V N ++  +++ I+ ++  +A     GLS GA  GI+IGV+  VALI
Sbjct: 387 KREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENGLSPGAIAGIVIGVVALVALI 444


>gi|19923195 carcinoembryonic antigen-related cell adhesion molecule
           1 isoform 1 precursor [Homo sapiens]
          Length = 526

 Score =  619 bits (1596), Expect = e-177
 Identities = 309/423 (73%), Positives = 339/423 (80%), Gaps = 5/423 (1%)

Query: 5   SAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQHLFG 64
           SAP HR  +PWQ LLLTASLLTFWNPPTTA+LT ES PFNVAEGKEVLLLVHNLPQ LFG
Sbjct: 5   SAPLHRVRVPWQGLLLTASLLTFWNPPTTAQLTTESMPFNVAEGKEVLLLVHNLPQQLFG 64

Query: 65  YSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFYTLHV 124
           YSWYKGERVDGNRQI+GY IGTQQATPGPA SGRE IYPNASLLIQN+ QNDTGFYTL V
Sbjct: 65  YSWYKGERVDGNRQIVGYAIGTQQATPGPANSGRETIYPNASLLIQNVTQNDTGFYTLQV 124

Query: 125 IKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNNQS 184
           IKSDLVNEEATGQF VYPELPKPSISSNNS PVEDKDAVAFTCEPETQD TYLWW+NNQS
Sbjct: 125 IKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPETQDTTYLWWINNQS 184

Query: 185 LPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTISP 244
           LPVSPRLQLSNGNRTLTL +VTRNDT  Y+CE QNPVSA RSD V LNV YGPD PTISP
Sbjct: 185 LPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANRSDPVTLNVTYGPDTPTISP 244

Query: 245 LNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQAHNS 304
            +T YR G NL+LSC+AASNPPAQYSW +NGTFQQSTQELFIPNITVNNSGSYTC A+NS
Sbjct: 245 SDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELFIPNITVNNSGSYTCHANNS 304

Query: 305 DTGLNRTTVTTITVYAEPP---KPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQ 361
            TG NRTTV TI V    P   KP I ++ +    D+D+V LTC       +  W+  NQ
Sbjct: 305 VTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQ 364

Query: 362 SLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYG--PDDPT 419
           SLP S R++LS  N TL++  V R D G Y C + N +S + SDP++LNV Y   P +  
Sbjct: 365 SLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENG 424

Query: 420 ISP 422
           +SP
Sbjct: 425 LSP 427



 Score =  376 bits (966), Expect = e-104
 Identities = 192/311 (61%), Positives = 222/311 (71%), Gaps = 4/311 (1%)

Query: 284 LFIPNITVNNSGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVAL 343
           L I N+T N++G YT Q   SD  +N        VY E PKP I+SNNSNPVED+DAVA 
Sbjct: 107 LLIQNVTQNDTGFYTLQVIKSDL-VNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAF 165

Query: 344 TCEPEIQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDH 403
           TCEPE Q+TTYLWW+NNQSLPVSPRLQLSN NRTLTLLSVTRND GPYEC IQN +S + 
Sbjct: 166 TCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANR 225

Query: 404 SDPVILNVLYGPDDPTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELF 463
           SDPV LNV YGPD PTISPS TYYRPG NLSLSC+AASNPPAQYSWLI+G  QQ TQELF
Sbjct: 226 SDPVTLNVTYGPDTPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELF 285

Query: 464 ISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELP---KPSISSNNSKPVEDKDAVA 520
           I NIT  NSG YTC ANNS +G +RTTVKTI V+   P   KP I ++ +    DKD+V 
Sbjct: 286 IPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVTELSPVVAKPQIKASKTTVTGDKDSVN 345

Query: 521 FTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSAN 580
            TC       +  W+   QSLP S R++LS GN TL++  V R DA  Y C + N +S N
Sbjct: 346 LTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPVKREDAGTYWCEVFNPISKN 405

Query: 581 RSDPVTLDVLY 591
           +SDP+ L+V Y
Sbjct: 406 QSDPIMLNVNY 416



 Score =  275 bits (703), Expect = 1e-73
 Identities = 139/214 (64%), Positives = 159/214 (74%), Gaps = 1/214 (0%)

Query: 462 LFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAF 521
           L I N+T+ ++G YT Q   S   +   T +   V  ELPKPSISSNNS PVEDKDAVAF
Sbjct: 107 LLIQNVTQNDTGFYTLQVIKSDLVNEEATGQ-FHVYPELPKPSISSNNSNPVEDKDAVAF 165

Query: 522 TCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANR 581
           TCEPE Q+TTYLWW+N QSLPVSPRLQLSNGNRTLTL +VTRND   Y C IQN VSANR
Sbjct: 166 TCEPETQDTTYLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNPVSANR 225

Query: 582 SDPVTLDVLYGPDTPIISPPDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQVLF 641
           SDPVTL+V YGPDTP ISP D+ Y  GANL+LSC++ASNP  QYSW ING  QQ TQ LF
Sbjct: 226 SDPVTLNVTYGPDTPTISPSDTYYRPGANLSLSCYAASNPPAQYSWLINGTFQQSTQELF 285

Query: 642 IAKITPNNNGTYACFVSNLATGRNNSIVKSITVS 675
           I  IT NN+G+Y C  +N  TG N + VK+I V+
Sbjct: 286 IPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVT 319



 Score = 69.7 bits (169), Expect = 9e-12
 Identities = 87/358 (24%), Positives = 152/358 (42%), Gaps = 47/358 (13%)

Query: 375 NRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTISPSYTYYRPGVN-- 432
           N +L + +VT+ND G Y   +     V+       +V   P+ P  S S     P  +  
Sbjct: 104 NASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVY--PELPKPSISSNNSNPVEDKD 161

Query: 433 -LSLSCHAASNPPAQYSWLIDGNIQQHTQELFISN---------ITEKNSGLYTCQANNS 482
            ++ +C   +     Y W I+      +  L +SN         +T  ++G Y C+  N 
Sbjct: 162 AVAFTCEPETQDTT-YLWWINNQSLPVSPRLQLSNGNRTLTLLSVTRNDTGPYECEIQNP 220

Query: 483 ASGHSRTTVK-TITVSAELPKPSISSNNSKPVEDKDAVAFTCE-PEAQNTTYLWWVNGQS 540
            S +    V   +T   + P  S S    +P  +     +    P AQ   Y W +NG  
Sbjct: 221 VSANRSDPVTLNVTYGPDTPTISPSDTYYRPGANLSLSCYAASNPPAQ---YSWLINGT- 276

Query: 541 LPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSA-NRSDPVTLDVLYGPDTPIIS 599
                        + L + N+T N++ +Y C   NSV+  NR+   T+ V     +P+++
Sbjct: 277 --------FQQSTQELFIPNITVNNSGSYTCHANNSVTGCNRTTVKTIIVT--ELSPVVA 326

Query: 600 PPD----SSYLSGA--NLNLSCHSASNP-SPQYSWRINGIPQ-------QHTQVLFIAKI 645
            P      + ++G   ++NL+C +     S ++ ++   +P        Q    L I  +
Sbjct: 327 KPQIKASKTTVTGDKDSVNLTCSTNDTGISIRWFFKNQSLPSSERMKLSQGNTTLSINPV 386

Query: 646 TPNNNGTYACFVSN-LATGRNNSIVKSITVSASGTSPGLSAGATVGIMIGVLVGVALI 702
              + GTY C V N ++  +++ I+ ++  +A     GLS GA  GI+IGV+  VALI
Sbjct: 387 KREDAGTYWCEVFNPISKNQSDPIMLNVNYNALPQENGLSPGAIAGIVIGVVALVALI 444


>gi|40255013 carcinoembryonic antigen-related cell adhesion molecule
           6 (non-specific cross reacting antigen) [Homo sapiens]
          Length = 344

 Score =  560 bits (1443), Expect = e-159
 Identities = 271/323 (83%), Positives = 282/323 (87%)

Query: 1   MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ 60
           M  PSAPP R  +PW+ +LLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLL HNLPQ
Sbjct: 1   MGPPSAPPCRLHVPWKEVLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLAHNLPQ 60

Query: 61  HLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFY 120
           +  GYSWYKGERVDGN  I+GYVIGTQQATPGPAYSGRE IYPNASLLIQN+ QNDTGFY
Sbjct: 61  NRIGYSWYKGERVDGNSLIVGYVIGTQQATPGPAYSGRETIYPNASLLIQNVTQNDTGFY 120

Query: 121 TLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWV 180
           TL VIKSDLVNEEATGQF VYPELPKPSISSNNS PVEDKDAVAFTCEPE Q+ TYLWWV
Sbjct: 121 TLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAFTCEPEVQNTTYLWWV 180

Query: 181 NNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAP 240
           N QSLPVSPRLQLSNGN TLTL +V RND  SY+CE QNP SA RSD V LNVLYGPD P
Sbjct: 181 NGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANRSDPVTLNVLYGPDGP 240

Query: 241 TISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQ 300
           TISP   +YR GENLNLSCHAASNPPAQYSWF+NGTFQQSTQELFIPNITVNNSGSY CQ
Sbjct: 241 TISPSKANYRPGENLNLSCHAASNPPAQYSWFINGTFQQSTQELFIPNITVNNSGSYMCQ 300

Query: 301 AHNSDTGLNRTTVTTITVYAEPP 323
           AHNS TGLNRTTVT ITV    P
Sbjct: 301 AHNSATGLNRTTVTMITVSGSAP 323



 Score =  300 bits (767), Expect = 4e-81
 Identities = 160/241 (66%), Positives = 177/241 (73%), Gaps = 3/241 (1%)

Query: 462 LFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAF 521
           L I N+T+ ++G YT Q   S   +   T +   V  ELPKPSISSNNS PVEDKDAVAF
Sbjct: 107 LLIQNVTQNDTGFYTLQVIKSDLVNEEATGQ-FHVYPELPKPSISSNNSNPVEDKDAVAF 165

Query: 522 TCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANR 581
           TCEPE QNTTYLWWVNGQSLPVSPRLQLSNGN TLTL +V RNDA +Y C IQN  SANR
Sbjct: 166 TCEPEVQNTTYLWWVNGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANR 225

Query: 582 SDPVTLDVLYGPDTPIISPPDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQVLF 641
           SDPVTL+VLYGPD P ISP  ++Y  G NLNLSCH+ASNP  QYSW ING  QQ TQ LF
Sbjct: 226 SDPVTLNVLYGPDGPTISPSKANYRPGENLNLSCHAASNPPAQYSWFINGTFQQSTQELF 285

Query: 642 IAKITPNNNGTYACFVSNLATGRNNSIVKSITVSASGTSPGLSAGATVGIMIGVLVGVAL 701
           I  IT NN+G+Y C   N ATG N + V  ITV  SG++P LSA ATVGI IGVL  VAL
Sbjct: 286 IPNITVNNSGSYMCQAHNSATGLNRTTVTMITV--SGSAPVLSAVATVGITIGVLARVAL 343

Query: 702 I 702
           I
Sbjct: 344 I 344



 Score =  300 bits (767), Expect = 4e-81
 Identities = 151/218 (69%), Positives = 164/218 (75%), Gaps = 1/218 (0%)

Query: 284 LFIPNITVNNSGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVAL 343
           L I N+T N++G YT Q   SD  +N        VY E PKP I+SNNSNPVED+DAVA 
Sbjct: 107 LLIQNVTQNDTGFYTLQVIKSDL-VNEEATGQFHVYPELPKPSISSNNSNPVEDKDAVAF 165

Query: 344 TCEPEIQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDH 403
           TCEPE+QNTTYLWWVN QSLPVSPRLQLSN N TLTLLSV RND G YEC IQN  S + 
Sbjct: 166 TCEPEVQNTTYLWWVNGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASANR 225

Query: 404 SDPVILNVLYGPDDPTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELF 463
           SDPV LNVLYGPD PTISPS   YRPG NL+LSCHAASNPPAQYSW I+G  QQ TQELF
Sbjct: 226 SDPVTLNVLYGPDGPTISPSKANYRPGENLNLSCHAASNPPAQYSWFINGTFQQSTQELF 285

Query: 464 ISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELP 501
           I NIT  NSG Y CQA+NSA+G +RTTV  ITVS   P
Sbjct: 286 IPNITVNNSGSYMCQAHNSATGLNRTTVTMITVSGSAP 323



 Score = 30.0 bits (66), Expect = 7.6
 Identities = 28/126 (22%), Positives = 46/126 (36%), Gaps = 9/126 (7%)

Query: 553 NRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISPPDSSYLSGANLN 612
           N +L + NVT+ND   Y   +  S   N        V      P IS  +S+ +   +  
Sbjct: 104 NASLLIQNVTQNDTGFYTLQVIKSDLVNEEATGQFHVYPELPKPSISSNNSNPVEDKDAV 163

Query: 613 LSCHSASNPSPQYSWRING--IP-------QQHTQVLFIAKITPNNNGTYACFVSNLATG 663
                    +  Y W +NG  +P             L +  +  N+ G+Y C + N A+ 
Sbjct: 164 AFTCEPEVQNTTYLWWVNGQSLPVSPRLQLSNGNMTLTLLSVKRNDAGSYECEIQNPASA 223

Query: 664 RNNSIV 669
             +  V
Sbjct: 224 NRSDPV 229


>gi|21314600 carcinoembryonic antigen-related cell adhesion molecule
           8 [Homo sapiens]
          Length = 349

 Score =  494 bits (1272), Expect = e-139
 Identities = 241/314 (76%), Positives = 260/314 (82%)

Query: 5   SAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQHLFG 64
           SAP  RW IPWQ LLLTASL TFWNPPTTA+LTIE+ P N AEGKEVLLLVHNLPQ   G
Sbjct: 5   SAPSCRWRIPWQGLLLTASLFTFWNPPTTAQLTIEAVPSNAAEGKEVLLLVHNLPQDPRG 64

Query: 65  YSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFYTLHV 124
           Y+WYKGE VD NR+IIGYVI  QQ TPGPAYS RE IYPNASLL++N+ +NDTG YTL V
Sbjct: 65  YNWYKGETVDANRRIIGYVISNQQITPGPAYSNRETIYPNASLLMRNVTRNDTGSYTLQV 124

Query: 125 IKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNNQS 184
           IK +L++EE TGQF V+PE PKPSISSNNS PVEDKDAVAFTCEPETQ+ TYLWWVN QS
Sbjct: 125 IKLNLMSEEVTGQFSVHPETPKPSISSNNSNPVEDKDAVAFTCEPETQNTTYLWWVNGQS 184

Query: 185 LPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTISP 244
           LPVSPRLQLSNGNRTLTL +VTRND   Y+CE QNP SA  SD V LNVLYGPDAPTISP
Sbjct: 185 LPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANFSDPVTLNVLYGPDAPTISP 244

Query: 245 LNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQAHNS 304
            +T Y +G NLNLSCHAASNPP+QYSW VNGTFQQ TQ+LFIPNIT  NSGSY C   NS
Sbjct: 245 SDTYYHAGVNLNLSCHAASNPPSQYSWSVNGTFQQYTQKLFIPNITTKNSGSYACHTTNS 304

Query: 305 DTGLNRTTVTTITV 318
            TG NRTTV  ITV
Sbjct: 305 ATGRNRTTVRMITV 318



 Score =  307 bits (787), Expect = 2e-83
 Identities = 160/244 (65%), Positives = 179/244 (73%), Gaps = 4/244 (1%)

Query: 462 LFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAF 521
           L + N+T  ++G YT Q     +  S       +V  E PKPSISSNNS PVEDKDAVAF
Sbjct: 107 LLMRNVTRNDTGSYTLQVIK-LNLMSEEVTGQFSVHPETPKPSISSNNSNPVEDKDAVAF 165

Query: 522 TCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANR 581
           TCEPE QNTTYLWWVNGQSLPVSPRLQLSNGNRTLTL +VTRND   Y C IQN  SAN 
Sbjct: 166 TCEPETQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNPASANF 225

Query: 582 SDPVTLDVLYGPDTPIISPPDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQVLF 641
           SDPVTL+VLYGPD P ISP D+ Y +G NLNLSCH+ASNP  QYSW +NG  QQ+TQ LF
Sbjct: 226 SDPVTLNVLYGPDAPTISPSDTYYHAGVNLNLSCHAASNPPSQYSWSVNGTFQQYTQKLF 285

Query: 642 IAKITPNNNGTYACFVSNLATGRNNSIVKSITVS---ASGTSPGLSAGATVGIMIGVLVG 698
           I  IT  N+G+YAC  +N ATGRN + V+ ITVS     G+SPGLSA ATV IMIGVL  
Sbjct: 286 IPNITTKNSGSYACHTTNSATGRNRTTVRMITVSDALVQGSSPGLSARATVSIMIGVLAR 345

Query: 699 VALI 702
           VALI
Sbjct: 346 VALI 349



 Score =  302 bits (773), Expect = 8e-82
 Identities = 161/291 (55%), Positives = 190/291 (65%), Gaps = 28/291 (9%)

Query: 241 TISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTF-------------QQSTQ----- 282
           TI  + ++   G+ + L  H     P  Y+W+   T              QQ T      
Sbjct: 37  TIEAVPSNAAEGKEVLLLVHNLPQDPRGYNWYKGETVDANRRIIGYVISNQQITPGPAYS 96

Query: 283 ---------ELFIPNITVNNSGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFITSNNSN 333
                     L + N+T N++GSYT Q    +  ++       +V+ E PKP I+SNNSN
Sbjct: 97  NRETIYPNASLLMRNVTRNDTGSYTLQVIKLNL-MSEEVTGQFSVHPETPKPSISSNNSN 155

Query: 334 PVEDEDAVALTCEPEIQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYEC 393
           PVED+DAVA TCEPE QNTTYLWWVN QSLPVSPRLQLSN NRTLTLLSVTRNDVGPYEC
Sbjct: 156 PVEDKDAVAFTCEPETQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYEC 215

Query: 394 GIQNKLSVDHSDPVILNVLYGPDDPTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDG 453
            IQN  S + SDPV LNVLYGPD PTISPS TYY  GVNL+LSCHAASNPP+QYSW ++G
Sbjct: 216 EIQNPASANFSDPVTLNVLYGPDAPTISPSDTYYHAGVNLNLSCHAASNPPSQYSWSVNG 275

Query: 454 NIQQHTQELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPS 504
             QQ+TQ+LFI NIT KNSG Y C   NSA+G +RTTV+ ITVS  L + S
Sbjct: 276 TFQQYTQKLFIPNITTKNSGSYACHTTNSATGRNRTTVRMITVSDALVQGS 326



 Score = 35.0 bits (79), Expect = 0.24
 Identities = 38/148 (25%), Positives = 62/148 (41%), Gaps = 16/148 (10%)

Query: 553 NRTLTLFNVTRNDARAYVCGIQNSVSAN-RSDPVTLDVLYGPDT--PIISPPDSSYLSGA 609
           N +L + NVTRND  +Y   +   +  N  S+ VT      P+T  P IS  +S+ +   
Sbjct: 104 NASLLMRNVTRNDTGSYTLQV---IKLNLMSEEVTGQFSVHPETPKPSISSNNSNPVEDK 160

Query: 610 NLNLSCHSASNPSPQYSWRING--IP-------QQHTQVLFIAKITPNNNGTYACFVSNL 660
           +           +  Y W +NG  +P           + L +  +T N+ G Y C + N 
Sbjct: 161 DAVAFTCEPETQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLLSVTRNDVGPYECEIQNP 220

Query: 661 ATGRNNSIVKSITVSASGTSPGLSAGAT 688
           A+  N S   ++ V     +P +S   T
Sbjct: 221 ASA-NFSDPVTLNVLYGPDAPTISPSDT 247


>gi|164663836 pregnancy specific beta-1-glycoprotein 11 isoform 1
           [Homo sapiens]
          Length = 335

 Score =  350 bits (898), Expect = 3e-96
 Identities = 186/329 (56%), Positives = 217/329 (65%), Gaps = 2/329 (0%)

Query: 5   SAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQHLFG 64
           SAPP    I W+ LLLTA LL FWN PTTA++ IE+ P  V+EGK+VLLLVHNLPQ+L G
Sbjct: 5   SAPPCTEHIKWKGLLLTALLLNFWNLPTTAQVMIEAQPPKVSEGKDVLLLVHNLPQNLTG 64

Query: 65  YSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFYTLHV 124
           Y WYKG+  D    I  YV+  Q    GPAYSGRE +Y NASLLIQN+ + D G YTLH+
Sbjct: 65  YIWYKGQIRDLYHYITSYVVDGQIIIYGPAYSGRETVYSNASLLIQNVTREDAGSYTLHI 124

Query: 125 IKSDLVNEEATGQFR--VYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNN 182
           IK        TG F   +Y E PKPSISS+N  P E  + V  TC PET DA+YLWW+N 
Sbjct: 125 IKRGDGTRGVTGYFTFTLYLETPKPSISSSNLNPREAMETVILTCNPETPDASYLWWMNG 184

Query: 183 QSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTI 242
           QSLP++ R+QLS  NRTL LF VT+     Y+CE  N  SA RSD V LN+L+GPD P I
Sbjct: 185 QSLPMTHRMQLSETNRTLFLFGVTKYTAGPYECEIWNSGSASRSDPVTLNLLHGPDLPRI 244

Query: 243 SPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQAH 302
            P  TSY SGENL+LSC A SNPPAQYSW +NG FQ S Q+LFIP IT  ++G Y C A 
Sbjct: 245 FPSVTSYYSGENLDLSCFANSNPPAQYSWTINGKFQLSGQKLFIPQITPKHNGLYACSAR 304

Query: 303 NSDTGLNRTTVTTITVYAEPPKPFITSNN 331
           NS TG   +T  TI V A P       NN
Sbjct: 305 NSATGEESSTSLTIRVIAPPGLGTFAFNN 333



 Score =  217 bits (553), Expect = 3e-56
 Identities = 116/231 (50%), Positives = 140/231 (60%), Gaps = 1/231 (0%)

Query: 280 STQELFIPNITVNNSGSYTCQAHNSDTGLNRTT-VTTITVYAEPPKPFITSNNSNPVEDE 338
           S   L I N+T  ++GSYT        G    T   T T+Y E PKP I+S+N NP E  
Sbjct: 103 SNASLLIQNVTREDAGSYTLHIIKRGDGTRGVTGYFTFTLYLETPKPSISSSNLNPREAM 162

Query: 339 DAVALTCEPEIQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNK 398
           + V LTC PE  + +YLWW+N QSLP++ R+QLS  NRTL L  VT+   GPYEC I N 
Sbjct: 163 ETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFLFGVTKYTAGPYECEIWNS 222

Query: 399 LSVDHSDPVILNVLYGPDDPTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQH 458
            S   SDPV LN+L+GPD P I PS T Y  G NL LSC A SNPPAQYSW I+G  Q  
Sbjct: 223 GSASRSDPVTLNLLHGPDLPRIFPSVTSYYSGENLDLSCFANSNPPAQYSWTINGKFQLS 282

Query: 459 TQELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPSISSNN 509
            Q+LFI  IT K++GLY C A NSA+G   +T  TI V A     + + NN
Sbjct: 283 GQKLFIPQITPKHNGLYACSARNSATGEESSTSLTIRVIAPPGLGTFAFNN 333



 Score =  207 bits (526), Expect = 3e-53
 Identities = 115/227 (50%), Positives = 140/227 (61%), Gaps = 4/227 (1%)

Query: 462 LFISNITEKNSGLYTCQANNSASGHSRTT-VKTITVSAELPKPSISSNNSKPVEDKDAVA 520
           L I N+T +++G YT        G    T   T T+  E PKPSISS+N  P E  + V 
Sbjct: 107 LLIQNVTREDAGSYTLHIIKRGDGTRGVTGYFTFTLYLETPKPSISSSNLNPREAMETVI 166

Query: 521 FTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSAN 580
            TC PE  + +YLWW+NGQSLP++ R+QLS  NRTL LF VT+  A  Y C I NS SA+
Sbjct: 167 LTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFLFGVTKYTAGPYECEIWNSGSAS 226

Query: 581 RSDPVTLDVLYGPDTPIISPPDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQVL 640
           RSDPVTL++L+GPD P I P  +SY SG NL+LSC + SNP  QYSW ING  Q   Q L
Sbjct: 227 RSDPVTLNLLHGPDLPRIFPSVTSYYSGENLDLSCFANSNPPAQYSWTINGKFQLSGQKL 286

Query: 641 FIAKITPNNNGTYACFVSNLATGRNNSIVKSITVSASGTSPGLSAGA 687
           FI +ITP +NG YAC   N ATG  +S   +I V A    PGL   A
Sbjct: 287 FIPQITPKHNGLYACSARNSATGEESSTSLTIRVIA---PPGLGTFA 330



 Score = 38.9 bits (89), Expect = 0.016
 Identities = 51/206 (24%), Positives = 74/206 (35%), Gaps = 52/206 (25%)

Query: 490 TVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWW-------------- 535
           T   + + A+ PK S         E KD +          T Y+W+              
Sbjct: 32  TTAQVMIEAQPPKVS---------EGKDVLLLVHNLPQNLTGYIWYKGQIRDLYHYITSY 82

Query: 536 -VNGQSLPVSPRL---QLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLY 591
            V+GQ +   P     +    N +L + NVTR DA +Y   I       R D       Y
Sbjct: 83  VVDGQIIIYGPAYSGRETVYSNASLLIQNVTREDAGSYTLHI-----IKRGDGTRGVTGY 137

Query: 592 GPDTPIISPPDSSYLSGANLN---------LSCHSASNPSPQYSWRING--IPQQH---- 636
              T  +  P  S +S +NLN         L+C +   P   Y W +NG  +P  H    
Sbjct: 138 FTFTLYLETPKPS-ISSSNLNPREAMETVILTC-NPETPDASYLWWMNGQSLPMTHRMQL 195

Query: 637 ---TQVLFIAKITPNNNGTYACFVSN 659
               + LF+  +T    G Y C + N
Sbjct: 196 SETNRTLFLFGVTKYTAGPYECEIWN 221


>gi|194097369 pregnancy specific beta-1-glycoprotein 5 [Homo
           sapiens]
          Length = 335

 Score =  349 bits (896), Expect = 4e-96
 Identities = 179/318 (56%), Positives = 219/318 (68%), Gaps = 2/318 (0%)

Query: 5   SAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQHLFG 64
           SAPP    I W+ LLLTASLL FWN P TA++TIE+ P  V+EGK+VLLLVHNLPQ+L G
Sbjct: 5   SAPPCTQHITWKGLLLTASLLNFWNLPITAQVTIEALPPKVSEGKDVLLLVHNLPQNLAG 64

Query: 65  YSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFYTLHV 124
           Y WYKG+ +D    I  YV+  Q    GPAY+GRE +Y NASLLIQN+ + D G YTLH+
Sbjct: 65  YIWYKGQLMDLYHYITSYVVDGQINIYGPAYTGRETVYSNASLLIQNVTREDAGSYTLHI 124

Query: 125 IKSDLVNEEATGQF--RVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNN 182
           IK        TG F   +Y +LPKP I+ NNSKP E+KD +AFTCEP++++ TY+WW+N 
Sbjct: 125 IKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIWWLNG 184

Query: 183 QSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTI 242
           QSLPVSPR++    NR L L +VTRN+T  Y+CE ++     RSD V LNVLYGPD P+I
Sbjct: 185 QSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRDGGMRSDPVTLNVLYGPDLPSI 244

Query: 243 SPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQAH 302
            P  T YRSGENL LSC A SNPPA+Y W +NG FQQS Q+L IP IT  + G YTC   
Sbjct: 245 YPSFTYYRSGENLYLSCFAESNPPAEYFWTINGKFQQSGQKLSIPQITTKHRGLYTCSVR 304

Query: 303 NSDTGLNRTTVTTITVYA 320
           NS TG   +   T+ V A
Sbjct: 305 NSATGKESSKSMTVEVSA 322



 Score =  227 bits (578), Expect = 3e-59
 Identities = 115/220 (52%), Positives = 144/220 (65%), Gaps = 1/220 (0%)

Query: 280 STQELFIPNITVNNSGSYTCQA-HNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDE 338
           S   L I N+T  ++GSYT       D     T   T  +Y + PKP+IT NNS P E++
Sbjct: 103 SNASLLIQNVTREDAGSYTLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENK 162

Query: 339 DAVALTCEPEIQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNK 398
           D +A TCEP+ +N TY+WW+N QSLPVSPR++   +NR L L SVTRN+ GPYEC I+++
Sbjct: 163 DVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDR 222

Query: 399 LSVDHSDPVILNVLYGPDDPTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQH 458
                SDPV LNVLYGPD P+I PS+TYYR G NL LSC A SNPPA+Y W I+G  QQ 
Sbjct: 223 DGGMRSDPVTLNVLYGPDLPSIYPSFTYYRSGENLYLSCFAESNPPAEYFWTINGKFQQS 282

Query: 459 TQELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSA 498
            Q+L I  IT K+ GLYTC   NSA+G   +   T+ VSA
Sbjct: 283 GQKLSIPQITTKHRGLYTCSVRNSATGKESSKSMTVEVSA 322



 Score =  199 bits (505), Expect = 9e-51
 Identities = 112/246 (45%), Positives = 145/246 (58%), Gaps = 15/246 (6%)

Query: 448 SWLIDGNIQQH------------TQELFISNITEKNSGLYTCQA-NNSASGHSRTTVKTI 494
           S+++DG I  +               L I N+T +++G YT             T   T 
Sbjct: 81  SYVVDGQINIYGPAYTGRETVYSNASLLIQNVTREDAGSYTLHIIKRGDRTRGVTGYFTF 140

Query: 495 TVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNR 554
            +  +LPKP I+ NNSKP E+KD +AFTCEP+++N TY+WW+NGQSLPVSPR++    NR
Sbjct: 141 NLYLKLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENR 200

Query: 555 TLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISPPDSSYLSGANLNLS 614
            L L +VTRN+   Y C I++     RSDPVTL+VLYGPD P I P  + Y SG NL LS
Sbjct: 201 ILILPSVTRNETGPYECEIRDRDGGMRSDPVTLNVLYGPDLPSIYPSFTYYRSGENLYLS 260

Query: 615 CHSASNPSPQYSWRINGIPQQHTQVLFIAKITPNNNGTYACFVSNLATGRNNSIVKSITV 674
           C + SNP  +Y W ING  QQ  Q L I +IT  + G Y C V N ATG+ +S  KS+TV
Sbjct: 261 CFAESNPPAEYFWTINGKFQQSGQKLSIPQITTKHRGLYTCSVRNSATGKESS--KSMTV 318

Query: 675 SASGTS 680
             S  S
Sbjct: 319 EVSAPS 324


>gi|194097367 pregnancy specific beta-1-glycoprotein 5 [Homo
           sapiens]
          Length = 335

 Score =  349 bits (896), Expect = 4e-96
 Identities = 179/318 (56%), Positives = 219/318 (68%), Gaps = 2/318 (0%)

Query: 5   SAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQHLFG 64
           SAPP    I W+ LLLTASLL FWN P TA++TIE+ P  V+EGK+VLLLVHNLPQ+L G
Sbjct: 5   SAPPCTQHITWKGLLLTASLLNFWNLPITAQVTIEALPPKVSEGKDVLLLVHNLPQNLAG 64

Query: 65  YSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFYTLHV 124
           Y WYKG+ +D    I  YV+  Q    GPAY+GRE +Y NASLLIQN+ + D G YTLH+
Sbjct: 65  YIWYKGQLMDLYHYITSYVVDGQINIYGPAYTGRETVYSNASLLIQNVTREDAGSYTLHI 124

Query: 125 IKSDLVNEEATGQF--RVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNN 182
           IK        TG F   +Y +LPKP I+ NNSKP E+KD +AFTCEP++++ TY+WW+N 
Sbjct: 125 IKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIWWLNG 184

Query: 183 QSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTI 242
           QSLPVSPR++    NR L L +VTRN+T  Y+CE ++     RSD V LNVLYGPD P+I
Sbjct: 185 QSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRDGGMRSDPVTLNVLYGPDLPSI 244

Query: 243 SPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQAH 302
            P  T YRSGENL LSC A SNPPA+Y W +NG FQQS Q+L IP IT  + G YTC   
Sbjct: 245 YPSFTYYRSGENLYLSCFAESNPPAEYFWTINGKFQQSGQKLSIPQITTKHRGLYTCSVR 304

Query: 303 NSDTGLNRTTVTTITVYA 320
           NS TG   +   T+ V A
Sbjct: 305 NSATGKESSKSMTVEVSA 322



 Score =  227 bits (578), Expect = 3e-59
 Identities = 115/220 (52%), Positives = 144/220 (65%), Gaps = 1/220 (0%)

Query: 280 STQELFIPNITVNNSGSYTCQA-HNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDE 338
           S   L I N+T  ++GSYT       D     T   T  +Y + PKP+IT NNS P E++
Sbjct: 103 SNASLLIQNVTREDAGSYTLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENK 162

Query: 339 DAVALTCEPEIQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNK 398
           D +A TCEP+ +N TY+WW+N QSLPVSPR++   +NR L L SVTRN+ GPYEC I+++
Sbjct: 163 DVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDR 222

Query: 399 LSVDHSDPVILNVLYGPDDPTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQH 458
                SDPV LNVLYGPD P+I PS+TYYR G NL LSC A SNPPA+Y W I+G  QQ 
Sbjct: 223 DGGMRSDPVTLNVLYGPDLPSIYPSFTYYRSGENLYLSCFAESNPPAEYFWTINGKFQQS 282

Query: 459 TQELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSA 498
            Q+L I  IT K+ GLYTC   NSA+G   +   T+ VSA
Sbjct: 283 GQKLSIPQITTKHRGLYTCSVRNSATGKESSKSMTVEVSA 322



 Score =  199 bits (505), Expect = 9e-51
 Identities = 112/246 (45%), Positives = 145/246 (58%), Gaps = 15/246 (6%)

Query: 448 SWLIDGNIQQH------------TQELFISNITEKNSGLYTCQA-NNSASGHSRTTVKTI 494
           S+++DG I  +               L I N+T +++G YT             T   T 
Sbjct: 81  SYVVDGQINIYGPAYTGRETVYSNASLLIQNVTREDAGSYTLHIIKRGDRTRGVTGYFTF 140

Query: 495 TVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNR 554
            +  +LPKP I+ NNSKP E+KD +AFTCEP+++N TY+WW+NGQSLPVSPR++    NR
Sbjct: 141 NLYLKLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENR 200

Query: 555 TLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISPPDSSYLSGANLNLS 614
            L L +VTRN+   Y C I++     RSDPVTL+VLYGPD P I P  + Y SG NL LS
Sbjct: 201 ILILPSVTRNETGPYECEIRDRDGGMRSDPVTLNVLYGPDLPSIYPSFTYYRSGENLYLS 260

Query: 615 CHSASNPSPQYSWRINGIPQQHTQVLFIAKITPNNNGTYACFVSNLATGRNNSIVKSITV 674
           C + SNP  +Y W ING  QQ  Q L I +IT  + G Y C V N ATG+ +S  KS+TV
Sbjct: 261 CFAESNPPAEYFWTINGKFQQSGQKLSIPQITTKHRGLYTCSVRNSATGKESS--KSMTV 318

Query: 675 SASGTS 680
             S  S
Sbjct: 319 EVSAPS 324


>gi|156616282 pregnancy specific beta-1-glycoprotein 2 [Homo
           sapiens]
          Length = 335

 Score =  348 bits (893), Expect = 1e-95
 Identities = 181/318 (56%), Positives = 213/318 (66%), Gaps = 2/318 (0%)

Query: 5   SAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQHLFG 64
           SAPP    I W+ LL+TASLL FWN PTTA++TIE+ P  V+EGK+VLLLVHNLPQ+L G
Sbjct: 5   SAPPCTEHIKWKGLLVTASLLNFWNLPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQNLTG 64

Query: 65  YSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFYTLHV 124
           Y WYKG+  D    I  YV+  Q    GPAYSGRE  Y NASLLIQN+ + D G YTLH+
Sbjct: 65  YIWYKGQIRDLYHYITSYVVDGQIIIYGPAYSGRETAYSNASLLIQNVTREDAGSYTLHI 124

Query: 125 IKSDLVNEEATGQFR--VYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNN 182
           IK        TG F   +Y E PKPSISS+N  P E  + V  TC+PET D +Y WW+N 
Sbjct: 125 IKRGDGTRGVTGYFTFTLYLETPKPSISSSNLNPREAMETVILTCDPETPDTSYQWWMNG 184

Query: 183 QSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTI 242
           QSLP++ R QLS  NRTL LF VT+     Y+CE +N  SA RSD V LN+L+GPD P I
Sbjct: 185 QSLPMTHRFQLSETNRTLFLFGVTKYTAGPYECEIRNSGSASRSDPVTLNLLHGPDLPRI 244

Query: 243 SPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQAH 302
            P  T+YRSG+NL LSC A SNPPAQYSW +NG FQQS Q LFIP IT  +SG Y C   
Sbjct: 245 HPSYTNYRSGDNLYLSCFANSNPPAQYSWTINGKFQQSGQNLFIPQITTKHSGLYVCSVR 304

Query: 303 NSDTGLNRTTVTTITVYA 320
           NS TG   +T  T+ V A
Sbjct: 305 NSATGEESSTSLTVKVSA 322



 Score =  226 bits (576), Expect = 6e-59
 Identities = 117/220 (53%), Positives = 139/220 (63%), Gaps = 1/220 (0%)

Query: 280 STQELFIPNITVNNSGSYTCQAHNSDTGLNRTT-VTTITVYAEPPKPFITSNNSNPVEDE 338
           S   L I N+T  ++GSYT        G    T   T T+Y E PKP I+S+N NP E  
Sbjct: 103 SNASLLIQNVTREDAGSYTLHIIKRGDGTRGVTGYFTFTLYLETPKPSISSSNLNPREAM 162

Query: 339 DAVALTCEPEIQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNK 398
           + V LTC+PE  +T+Y WW+N QSLP++ R QLS  NRTL L  VT+   GPYEC I+N 
Sbjct: 163 ETVILTCDPETPDTSYQWWMNGQSLPMTHRFQLSETNRTLFLFGVTKYTAGPYECEIRNS 222

Query: 399 LSVDHSDPVILNVLYGPDDPTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQH 458
            S   SDPV LN+L+GPD P I PSYT YR G NL LSC A SNPPAQYSW I+G  QQ 
Sbjct: 223 GSASRSDPVTLNLLHGPDLPRIHPSYTNYRSGDNLYLSCFANSNPPAQYSWTINGKFQQS 282

Query: 459 TQELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSA 498
            Q LFI  IT K+SGLY C   NSA+G   +T  T+ VSA
Sbjct: 283 GQNLFIPQITTKHSGLYVCSVRNSATGEESSTSLTVKVSA 322



 Score =  204 bits (520), Expect = 2e-52
 Identities = 110/217 (50%), Positives = 138/217 (63%), Gaps = 1/217 (0%)

Query: 462 LFISNITEKNSGLYTCQANNSASGHSRTT-VKTITVSAELPKPSISSNNSKPVEDKDAVA 520
           L I N+T +++G YT        G    T   T T+  E PKPSISS+N  P E  + V 
Sbjct: 107 LLIQNVTREDAGSYTLHIIKRGDGTRGVTGYFTFTLYLETPKPSISSSNLNPREAMETVI 166

Query: 521 FTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSAN 580
            TC+PE  +T+Y WW+NGQSLP++ R QLS  NRTL LF VT+  A  Y C I+NS SA+
Sbjct: 167 LTCDPETPDTSYQWWMNGQSLPMTHRFQLSETNRTLFLFGVTKYTAGPYECEIRNSGSAS 226

Query: 581 RSDPVTLDVLYGPDTPIISPPDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQVL 640
           RSDPVTL++L+GPD P I P  ++Y SG NL LSC + SNP  QYSW ING  QQ  Q L
Sbjct: 227 RSDPVTLNLLHGPDLPRIHPSYTNYRSGDNLYLSCFANSNPPAQYSWTINGKFQQSGQNL 286

Query: 641 FIAKITPNNNGTYACFVSNLATGRNNSIVKSITVSAS 677
           FI +IT  ++G Y C V N ATG  +S   ++ VSAS
Sbjct: 287 FIPQITTKHSGLYVCSVRNSATGEESSTSLTVKVSAS 323



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 52/206 (25%), Positives = 75/206 (36%), Gaps = 52/206 (25%)

Query: 490 TVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWW-------------- 535
           T   +T+ A+ PK S         E KD +          T Y+W+              
Sbjct: 32  TTAQVTIEAQPPKVS---------EGKDVLLLVHNLPQNLTGYIWYKGQIRDLYHYITSY 82

Query: 536 -VNGQSLPVSPRL---QLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLY 591
            V+GQ +   P     + +  N +L + NVTR DA +Y   I       R D       Y
Sbjct: 83  VVDGQIIIYGPAYSGRETAYSNASLLIQNVTREDAGSYTLHI-----IKRGDGTRGVTGY 137

Query: 592 GPDTPIISPPDSSYLSGANLN---------LSCHSASNPSPQYSWRING--IPQQH---- 636
              T  +  P  S +S +NLN         L+C     P   Y W +NG  +P  H    
Sbjct: 138 FTFTLYLETPKPS-ISSSNLNPREAMETVILTC-DPETPDTSYQWWMNGQSLPMTHRFQL 195

Query: 637 ---TQVLFIAKITPNNNGTYACFVSN 659
               + LF+  +T    G Y C + N
Sbjct: 196 SETNRTLFLFGVTKYTAGPYECEIRN 221


>gi|47419900 pregnancy specific beta-1-glycoprotein 4 isoform 2
           [Homo sapiens]
          Length = 326

 Score =  344 bits (883), Expect = 1e-94
 Identities = 179/316 (56%), Positives = 214/316 (67%), Gaps = 2/316 (0%)

Query: 5   SAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQHLFG 64
           SAPP    I W+ +LLTASLL FWNPPTTA++TIE+ P  V+EGK+VLLLVHNLPQ+L G
Sbjct: 5   SAPPCTQRITWKGVLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQNLAG 64

Query: 65  YSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFYTLHV 124
           Y WYKG+       I  YV+  Q+   GPAYSGRE +Y NASLLIQN+ Q D G YTLH+
Sbjct: 65  YIWYKGQMTYLYHYITSYVVDGQRIIYGPAYSGRERVYSNASLLIQNVTQEDAGSYTLHI 124

Query: 125 IKSDLVNEEATGQFR--VYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNN 182
           IK        TG F   ++ E PKPSISS+N  P E  +AV  TC+P T  A+Y WW+N 
Sbjct: 125 IKRRDGTGGVTGHFTFTLHLETPKPSISSSNLNPREAMEAVILTCDPATPAASYQWWMNG 184

Query: 183 QSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTI 242
           QSLP++ RLQLS  NRTL +F VT+     Y+CE +NPVSA RSD V LN+L+GPD P+I
Sbjct: 185 QSLPMTHRLQLSKTNRTLFIFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLHGPDLPSI 244

Query: 243 SPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQAH 302
            P  T YRSGENL LSC A SNP AQYSW +NG FQ S Q+L IP IT  +SG Y C   
Sbjct: 245 YPSFTYYRSGENLYLSCFAESNPRAQYSWTINGKFQLSGQKLSIPQITTKHSGLYACSVR 304

Query: 303 NSDTGLNRTTVTTITV 318
           NS TG   +   T+ V
Sbjct: 305 NSATGKESSKSITVKV 320



 Score =  211 bits (536), Expect = 2e-54
 Identities = 110/219 (50%), Positives = 137/219 (62%), Gaps = 1/219 (0%)

Query: 280 STQELFIPNITVNNSGSYTCQAHNSDTGLNRTTVT-TITVYAEPPKPFITSNNSNPVEDE 338
           S   L I N+T  ++GSYT        G    T   T T++ E PKP I+S+N NP E  
Sbjct: 103 SNASLLIQNVTQEDAGSYTLHIIKRRDGTGGVTGHFTFTLHLETPKPSISSSNLNPREAM 162

Query: 339 DAVALTCEPEIQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNK 398
           +AV LTC+P     +Y WW+N QSLP++ RLQLS  NRTL +  VT+   GPYEC I+N 
Sbjct: 163 EAVILTCDPATPAASYQWWMNGQSLPMTHRLQLSKTNRTLFIFGVTKYIAGPYECEIRNP 222

Query: 399 LSVDHSDPVILNVLYGPDDPTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQH 458
           +S   SDPV LN+L+GPD P+I PS+TYYR G NL LSC A SNP AQYSW I+G  Q  
Sbjct: 223 VSASRSDPVTLNLLHGPDLPSIYPSFTYYRSGENLYLSCFAESNPRAQYSWTINGKFQLS 282

Query: 459 TQELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVS 497
            Q+L I  IT K+SGLY C   NSA+G   +   T+ VS
Sbjct: 283 GQKLSIPQITTKHSGLYACSVRNSATGKESSKSITVKVS 321



 Score =  199 bits (505), Expect = 9e-51
 Identities = 110/217 (50%), Positives = 137/217 (63%), Gaps = 3/217 (1%)

Query: 462 LFISNITEKNSGLYTCQANNSASGHSRTTVK-TITVSAELPKPSISSNNSKPVEDKDAVA 520
           L I N+T++++G YT        G    T   T T+  E PKPSISS+N  P E  +AV 
Sbjct: 107 LLIQNVTQEDAGSYTLHIIKRRDGTGGVTGHFTFTLHLETPKPSISSSNLNPREAMEAVI 166

Query: 521 FTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSAN 580
            TC+P     +Y WW+NGQSLP++ RLQLS  NRTL +F VT+  A  Y C I+N VSA+
Sbjct: 167 LTCDPATPAASYQWWMNGQSLPMTHRLQLSKTNRTLFIFGVTKYIAGPYECEIRNPVSAS 226

Query: 581 RSDPVTLDVLYGPDTPIISPPDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQVL 640
           RSDPVTL++L+GPD P I P  + Y SG NL LSC + SNP  QYSW ING  Q   Q L
Sbjct: 227 RSDPVTLNLLHGPDLPSIYPSFTYYRSGENLYLSCFAESNPRAQYSWTINGKFQLSGQKL 286

Query: 641 FIAKITPNNNGTYACFVSNLATGRNNSIVKSITVSAS 677
            I +IT  ++G YAC V N ATG+ +S  KSITV  S
Sbjct: 287 SIPQITTKHSGLYACSVRNSATGKESS--KSITVKVS 321


>gi|5901930 carcinoembryonic antigen-related cell adhesion molecule
           7 [Homo sapiens]
          Length = 265

 Score =  324 bits (830), Expect = 2e-88
 Identities = 159/236 (67%), Positives = 183/236 (77%), Gaps = 1/236 (0%)

Query: 1   MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ 60
           M SPSA P+R CIPWQ LLLTASLLTFWN P +A+  I+  PFNVAEGKEVLL+VHN  Q
Sbjct: 1   MGSPSACPYRVCIPWQGLLLTASLLTFWNLPNSAQTNIDVVPFNVAEGKEVLLVVHNESQ 60

Query: 61  HLFGYSWYKGERVDGNRQIIGYVIG-TQQATPGPAYSGREIIYPNASLLIQNIIQNDTGF 119
           +L+GY+WYKGERV  N +IIGYV   +Q+  PGPA++GRE IYPN +LLIQN+  ND GF
Sbjct: 61  NLYGYNWYKGERVHANYRIIGYVKNISQENAPGPAHNGRETIYPNGTLLIQNVTHNDAGF 120

Query: 120 YTLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWW 179
           YTLHVIK +LVNEE T QF V+ E PKPSI+SNN  PVE+KD V  TC+PETQ+ TYLWW
Sbjct: 121 YTLHVIKENLVNEEVTRQFYVFSEPPKPSITSNNFNPVENKDIVVLTCQPETQNTTYLWW 180

Query: 180 VNNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLY 235
           VNNQSL VSPRL LS  NRTL L + T+ND   Y+CE QNPV A RSD V LNV Y
Sbjct: 181 VNNQSLLVSPRLLLSTDNRTLVLLSATKNDIGPYECEIQNPVGASRSDPVTLNVRY 236



 Score =  162 bits (410), Expect = 1e-39
 Identities = 92/183 (50%), Positives = 113/183 (61%), Gaps = 11/183 (6%)

Query: 234 LYGPDAPTISPLNTSYRS-GENLNLSCHAASNPP--AQYSWFVNGTFQQSTQELFIPNIT 290
           LYG +      ++ +YR  G   N+S   A  P    + + + NGT       L I N+T
Sbjct: 62  LYGYNWYKGERVHANYRIIGYVKNISQENAPGPAHNGRETIYPNGT-------LLIQNVT 114

Query: 291 VNNSGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQ 350
            N++G YT      +  +N        V++EPPKP ITSNN NPVE++D V LTC+PE Q
Sbjct: 115 HNDAGFYTLHVIKENL-VNEEVTRQFYVFSEPPKPSITSNNFNPVENKDIVVLTCQPETQ 173

Query: 351 NTTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILN 410
           NTTYLWWVNNQSL VSPRL LS DNRTL LLS T+ND+GPYEC IQN +    SDPV LN
Sbjct: 174 NTTYLWWVNNQSLLVSPRLLLSTDNRTLVLLSATKNDIGPYECEIQNPVGASRSDPVTLN 233

Query: 411 VLY 413
           V Y
Sbjct: 234 VRY 236



 Score =  141 bits (355), Expect = 2e-33
 Identities = 76/143 (53%), Positives = 91/143 (63%), Gaps = 3/143 (2%)

Query: 462 LFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAF 521
           L I N+T  ++G YT         +   T +   V +E PKPSI+SNN  PVE+KD V  
Sbjct: 108 LLIQNVTHNDAGFYTLHVIKENLVNEEVT-RQFYVFSEPPKPSITSNNFNPVENKDIVVL 166

Query: 522 TCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANR 581
           TC+PE QNTTYLWWVN QSL VSPRL LS  NRTL L + T+ND   Y C IQN V A+R
Sbjct: 167 TCQPETQNTTYLWWVNNQSLLVSPRLLLSTDNRTLVLLSATKNDIGPYECEIQNPVGASR 226

Query: 582 SDPVTLDVLYGPDTPIISPPDSS 604
           SDPVTL+V Y  ++   S PD S
Sbjct: 227 SDPVTLNVRY--ESVQASSPDLS 247



 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 44/161 (27%), Positives = 68/161 (42%), Gaps = 11/161 (6%)

Query: 553 NRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISPPDSSYLSGANLN 612
           N TL + NVT NDA  Y   +      N        V   P  P I+  + + +   ++ 
Sbjct: 105 NGTLLIQNVTHNDAGFYTLHVIKENLVNEEVTRQFYVFSEPPKPSITSNNFNPVENKDIV 164

Query: 613 LSCHSASNPSPQYSWRING---------IPQQHTQVLFIAKITPNNNGTYACFVSN-LAT 662
           +        +  Y W +N          +     + L +   T N+ G Y C + N +  
Sbjct: 165 VLTCQPETQNTTYLWWVNNQSLLVSPRLLLSTDNRTLVLLSATKNDIGPYECEIQNPVGA 224

Query: 663 GRNNSIVKSITV-SASGTSPGLSAGATVGIMIGVLVGVALI 702
            R++ +  ++   S   +SP LSAG  V IMIGVL G+ALI
Sbjct: 225 SRSDPVTLNVRYESVQASSPDLSAGTAVSIMIGVLAGMALI 265



 Score = 30.8 bits (68), Expect = 4.5
 Identities = 34/151 (22%), Positives = 61/151 (40%), Gaps = 19/151 (12%)

Query: 375 NRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTISPSYTYYRPGVN-- 432
           N TL + +VT ND G Y   +  +  V+        V   P  P+I+ +   + P  N  
Sbjct: 105 NGTLLIQNVTHNDAGFYTLHVIKENLVNEEVTRQFYVFSEPPKPSITSN--NFNPVENKD 162

Query: 433 -LSLSCHAASNPPAQYSWLIDGN---------IQQHTQELFISNITEKNSGLYTCQANNS 482
            + L+C   +     Y W ++           +    + L + + T+ + G Y C+  N 
Sbjct: 163 IVVLTCQPETQ-NTTYLWWVNNQSLLVSPRLLLSTDNRTLVLLSATKNDIGPYECEIQNP 221

Query: 483 ASGHSRTTVKTITV---SAELPKPSISSNNS 510
             G SR+   T+ V   S +   P +S+  +
Sbjct: 222 V-GASRSDPVTLNVRYESVQASSPDLSAGTA 251


>gi|194328710 pregnancy specific beta-1-glycoprotein 8 isoform b
           [Homo sapiens]
          Length = 419

 Score =  295 bits (754), Expect = 1e-79
 Identities = 178/406 (43%), Positives = 229/406 (56%), Gaps = 25/406 (6%)

Query: 5   SAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQHLFG 64
           SAPP    I W+ LLLTASLL FWNPPTTA++TIE+ P  V+EGK+VLLLVHNLPQ+L G
Sbjct: 5   SAPPCTQRITWKGLLLTASLLNFWNPPTTAQVTIEAQPTKVSEGKDVLLLVHNLPQNLTG 64

Query: 65  YSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFYTLHV 124
           Y WYKG+  D    I  YV+  Q    GPAYSGRE IY NASLLIQN+ Q D G YTLH+
Sbjct: 65  YIWYKGQIRDLYHYITSYVVDGQIIIYGPAYSGRETIYSNASLLIQNVTQEDAGSYTLHI 124

Query: 125 IKSDLVNEEATGQ--FRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNN 182
           I     N   TG   F +Y E PKPSISS+   P E  +AV+ TC+PET DA+YLWW+N 
Sbjct: 125 IMGGDENRGVTGHFTFTLYLETPKPSISSSKLNPREAMEAVSLTCDPETPDASYLWWMNG 184

Query: 183 QSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTI 242
           QSLP+S RLQLS  NRTL L  VT+     Y+CE +NPVSA RSD   LN+L     P I
Sbjct: 185 QSLPMSHRLQLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPFTLNLLPKLPKPYI 244

Query: 243 SPLNTSYRSGEN-LNLSCHAASNPPAQYSWFVNGTFQQ---------STQELFIPNITVN 292
           +  N   R  ++ LN +C   S     Y W++NG               + L +P++T N
Sbjct: 245 TINNLKPRENKDVLNFTCEPKSE-NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRN 303

Query: 293 NSGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQ-N 351
            +G Y C+  +   G+    VT   +Y  P  P I  + +      + + L+C  +    
Sbjct: 304 ETGPYQCEIRDQYGGIRSYPVTLNVLYG-PDLPRIYPSFTY-YRSGEVLYLSCSADSNPP 361

Query: 352 TTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQN 397
             Y W +N        + QLS   + L +  +T    G Y C ++N
Sbjct: 362 AQYSWTING-------KFQLS--GQKLFIPQITTKHSGLYACSVRN 398



 Score =  229 bits (585), Expect = 5e-60
 Identities = 129/313 (41%), Positives = 177/313 (56%), Gaps = 14/313 (4%)

Query: 197 NRTLTLFNVTRNDTASYKCETQNPVSARR--SDSVILNVLYGPDAPTISPLNTSYRSG-E 253
           N +L + NVT+ D  SY           R  +      +      P+IS    + R   E
Sbjct: 104 NASLLIQNVTQEDAGSYTLHIIMGGDENRGVTGHFTFTLYLETPKPSISSSKLNPREAME 163

Query: 254 NLNLSCHAASNPPAQYSWFVNGT---------FQQSTQELFIPNITVNNSGSYTCQAHNS 304
            ++L+C   + P A Y W++NG            ++ + LF+  +T   +G Y C+  N 
Sbjct: 164 AVSLTCDPET-PDASYLWWMNGQSLPMSHRLQLSETNRTLFLLGVTKYTAGPYECEIRNP 222

Query: 305 DTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQSLP 364
               +R+   T+ +  + PKP+IT NN  P E++D +  TCEP+ +N TY+WW+N QSLP
Sbjct: 223 -VSASRSDPFTLNLLPKLPKPYITINNLKPRENKDVLNFTCEPKSENYTYIWWLNGQSLP 281

Query: 365 VSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTISPSY 424
           VSPR++   +NR L L SVTRN+ GPY+C I+++     S PV LNVLYGPD P I PS+
Sbjct: 282 VSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGGIRSYPVTLNVLYGPDLPRIYPSF 341

Query: 425 TYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTCQANNSAS 484
           TYYR G  L LSC A SNPPAQYSW I+G  Q   Q+LFI  IT K+SGLY C   NSA+
Sbjct: 342 TYYRSGEVLYLSCSADSNPPAQYSWTINGKFQLSGQKLFIPQITTKHSGLYACSVRNSAT 401

Query: 485 GHSRTTVKTITVS 497
           G   +   T+ VS
Sbjct: 402 GKESSKSMTVKVS 414



 Score =  215 bits (547), Expect = 1e-55
 Identities = 146/402 (36%), Positives = 205/402 (50%), Gaps = 49/402 (12%)

Query: 309 NRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWW----------- 357
           N  T   +T+ A+P K           E +D + L        T Y+W+           
Sbjct: 29  NPPTTAQVTIEAQPTKVS---------EGKDVLLLVHNLPQNLTGYIWYKGQIRDLYHYI 79

Query: 358 ----VNNQSLPVSPRL---QLSNDNRTLTLLSVTRNDVGPYEC-----GIQNKLSVDHSD 405
               V+ Q +   P     +    N +L + +VT+ D G Y       G +N+    H  
Sbjct: 80  TSYVVDGQIIIYGPAYSGRETIYSNASLLIQNVTQEDAGSYTLHIIMGGDENRGVTGH-- 137

Query: 406 PVILNVLYGPDDPTISPSYTYYRPGVN-LSLSCHAASNPPAQYSWLIDGN---------I 455
                +      P+IS S    R  +  +SL+C   + P A Y W ++G          +
Sbjct: 138 -FTFTLYLETPKPSISSSKLNPREAMEAVSLTCDPET-PDASYLWWMNGQSLPMSHRLQL 195

Query: 456 QQHTQELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVED 515
            +  + LF+  +T+  +G Y C+  N  S  SR+   T+ +  +LPKP I+ NN KP E+
Sbjct: 196 SETNRTLFLLGVTKYTAGPYECEIRNPVSA-SRSDPFTLNLLPKLPKPYITINNLKPREN 254

Query: 516 KDAVAFTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQN 575
           KD + FTCEP+++N TY+WW+NGQSLPVSPR++    NR L L +VTRN+   Y C I++
Sbjct: 255 KDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRD 314

Query: 576 SVSANRSDPVTLDVLYGPDTPIISPPDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQ 635
                RS PVTL+VLYGPD P I P  + Y SG  L LSC + SNP  QYSW ING  Q 
Sbjct: 315 QYGGIRSYPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNPPAQYSWTINGKFQL 374

Query: 636 HTQVLFIAKITPNNNGTYACFVSNLATGRNNSIVKSITVSAS 677
             Q LFI +IT  ++G YAC V N ATG+ +S  KS+TV  S
Sbjct: 375 SGQKLFIPQITTKHSGLYACSVRNSATGKESS--KSMTVKVS 414



 Score =  202 bits (513), Expect = 1e-51
 Identities = 103/215 (47%), Positives = 132/215 (61%)

Query: 104 NASLLIQNIIQNDTGFYTLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAV 163
           N +L +  + +   G Y   +      +        + P+LPKP I+ NN KP E+KD +
Sbjct: 199 NRTLFLLGVTKYTAGPYECEIRNPVSASRSDPFTLNLLPKLPKPYITINNLKPRENKDVL 258

Query: 164 AFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSA 223
            FTCEP++++ TY+WW+N QSLPVSPR++    NR L L +VTRN+T  Y+CE ++    
Sbjct: 259 NFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGG 318

Query: 224 RRSDSVILNVLYGPDAPTISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQE 283
            RS  V LNVLYGPD P I P  T YRSGE L LSC A SNPPAQYSW +NG FQ S Q+
Sbjct: 319 IRSYPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNPPAQYSWTINGKFQLSGQK 378

Query: 284 LFIPNITVNNSGSYTCQAHNSDTGLNRTTVTTITV 318
           LFIP IT  +SG Y C   NS TG   +   T+ V
Sbjct: 379 LFIPQITTKHSGLYACSVRNSATGKESSKSMTVKV 413


>gi|51510887 pregnancy specific beta-1-glycoprotein 8 isoform a
           [Homo sapiens]
          Length = 426

 Score =  295 bits (754), Expect = 1e-79
 Identities = 178/406 (43%), Positives = 229/406 (56%), Gaps = 25/406 (6%)

Query: 5   SAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQHLFG 64
           SAPP    I W+ LLLTASLL FWNPPTTA++TIE+ P  V+EGK+VLLLVHNLPQ+L G
Sbjct: 5   SAPPCTQRITWKGLLLTASLLNFWNPPTTAQVTIEAQPTKVSEGKDVLLLVHNLPQNLTG 64

Query: 65  YSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFYTLHV 124
           Y WYKG+  D    I  YV+  Q    GPAYSGRE IY NASLLIQN+ Q D G YTLH+
Sbjct: 65  YIWYKGQIRDLYHYITSYVVDGQIIIYGPAYSGRETIYSNASLLIQNVTQEDAGSYTLHI 124

Query: 125 IKSDLVNEEATGQ--FRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNN 182
           I     N   TG   F +Y E PKPSISS+   P E  +AV+ TC+PET DA+YLWW+N 
Sbjct: 125 IMGGDENRGVTGHFTFTLYLETPKPSISSSKLNPREAMEAVSLTCDPETPDASYLWWMNG 184

Query: 183 QSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTI 242
           QSLP+S RLQLS  NRTL L  VT+     Y+CE +NPVSA RSD   LN+L     P I
Sbjct: 185 QSLPMSHRLQLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPFTLNLLPKLPKPYI 244

Query: 243 SPLNTSYRSGEN-LNLSCHAASNPPAQYSWFVNGTFQQ---------STQELFIPNITVN 292
           +  N   R  ++ LN +C   S     Y W++NG               + L +P++T N
Sbjct: 245 TINNLKPRENKDVLNFTCEPKSE-NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRN 303

Query: 293 NSGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQ-N 351
            +G Y C+  +   G+    VT   +Y  P  P I  + +      + + L+C  +    
Sbjct: 304 ETGPYQCEIRDQYGGIRSYPVTLNVLYG-PDLPRIYPSFTY-YRSGEVLYLSCSADSNPP 361

Query: 352 TTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQN 397
             Y W +N        + QLS   + L +  +T    G Y C ++N
Sbjct: 362 AQYSWTING-------KFQLS--GQKLFIPQITTKHSGLYACSVRN 398



 Score =  230 bits (586), Expect = 4e-60
 Identities = 129/315 (40%), Positives = 178/315 (56%), Gaps = 14/315 (4%)

Query: 197 NRTLTLFNVTRNDTASYKCETQNPVSARR--SDSVILNVLYGPDAPTISPLNTSYRSG-E 253
           N +L + NVT+ D  SY           R  +      +      P+IS    + R   E
Sbjct: 104 NASLLIQNVTQEDAGSYTLHIIMGGDENRGVTGHFTFTLYLETPKPSISSSKLNPREAME 163

Query: 254 NLNLSCHAASNPPAQYSWFVNGT---------FQQSTQELFIPNITVNNSGSYTCQAHNS 304
            ++L+C   + P A Y W++NG            ++ + LF+  +T   +G Y C+  N 
Sbjct: 164 AVSLTCDPET-PDASYLWWMNGQSLPMSHRLQLSETNRTLFLLGVTKYTAGPYECEIRNP 222

Query: 305 DTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQSLP 364
               +R+   T+ +  + PKP+IT NN  P E++D +  TCEP+ +N TY+WW+N QSLP
Sbjct: 223 -VSASRSDPFTLNLLPKLPKPYITINNLKPRENKDVLNFTCEPKSENYTYIWWLNGQSLP 281

Query: 365 VSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTISPSY 424
           VSPR++   +NR L L SVTRN+ GPY+C I+++     S PV LNVLYGPD P I PS+
Sbjct: 282 VSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGGIRSYPVTLNVLYGPDLPRIYPSF 341

Query: 425 TYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTCQANNSAS 484
           TYYR G  L LSC A SNPPAQYSW I+G  Q   Q+LFI  IT K+SGLY C   NSA+
Sbjct: 342 TYYRSGEVLYLSCSADSNPPAQYSWTINGKFQLSGQKLFIPQITTKHSGLYACSVRNSAT 401

Query: 485 GHSRTTVKTITVSAE 499
           G   +   T+ VS +
Sbjct: 402 GKESSKSMTVKVSGK 416



 Score =  217 bits (553), Expect = 3e-56
 Identities = 147/403 (36%), Positives = 206/403 (51%), Gaps = 49/403 (12%)

Query: 309 NRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWW----------- 357
           N  T   +T+ A+P K           E +D + L        T Y+W+           
Sbjct: 29  NPPTTAQVTIEAQPTKVS---------EGKDVLLLVHNLPQNLTGYIWYKGQIRDLYHYI 79

Query: 358 ----VNNQSLPVSPRL---QLSNDNRTLTLLSVTRNDVGPYEC-----GIQNKLSVDHSD 405
               V+ Q +   P     +    N +L + +VT+ D G Y       G +N+    H  
Sbjct: 80  TSYVVDGQIIIYGPAYSGRETIYSNASLLIQNVTQEDAGSYTLHIIMGGDENRGVTGH-- 137

Query: 406 PVILNVLYGPDDPTISPSYTYYRPGVN-LSLSCHAASNPPAQYSWLIDGN---------I 455
                +      P+IS S    R  +  +SL+C   + P A Y W ++G          +
Sbjct: 138 -FTFTLYLETPKPSISSSKLNPREAMEAVSLTCDPET-PDASYLWWMNGQSLPMSHRLQL 195

Query: 456 QQHTQELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVED 515
            +  + LF+  +T+  +G Y C+  N  S  SR+   T+ +  +LPKP I+ NN KP E+
Sbjct: 196 SETNRTLFLLGVTKYTAGPYECEIRNPVSA-SRSDPFTLNLLPKLPKPYITINNLKPREN 254

Query: 516 KDAVAFTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQN 575
           KD + FTCEP+++N TY+WW+NGQSLPVSPR++    NR L L +VTRN+   Y C I++
Sbjct: 255 KDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRD 314

Query: 576 SVSANRSDPVTLDVLYGPDTPIISPPDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQ 635
                RS PVTL+VLYGPD P I P  + Y SG  L LSC + SNP  QYSW ING  Q 
Sbjct: 315 QYGGIRSYPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNPPAQYSWTINGKFQL 374

Query: 636 HTQVLFIAKITPNNNGTYACFVSNLATGRNNSIVKSITVSASG 678
             Q LFI +IT  ++G YAC V N ATG+ +S  KS+TV  SG
Sbjct: 375 SGQKLFIPQITTKHSGLYACSVRNSATGKESS--KSMTVKVSG 415



 Score =  202 bits (513), Expect = 1e-51
 Identities = 103/215 (47%), Positives = 132/215 (61%)

Query: 104 NASLLIQNIIQNDTGFYTLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAV 163
           N +L +  + +   G Y   +      +        + P+LPKP I+ NN KP E+KD +
Sbjct: 199 NRTLFLLGVTKYTAGPYECEIRNPVSASRSDPFTLNLLPKLPKPYITINNLKPRENKDVL 258

Query: 164 AFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSA 223
            FTCEP++++ TY+WW+N QSLPVSPR++    NR L L +VTRN+T  Y+CE ++    
Sbjct: 259 NFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGG 318

Query: 224 RRSDSVILNVLYGPDAPTISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQE 283
            RS  V LNVLYGPD P I P  T YRSGE L LSC A SNPPAQYSW +NG FQ S Q+
Sbjct: 319 IRSYPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNPPAQYSWTINGKFQLSGQK 378

Query: 284 LFIPNITVNNSGSYTCQAHNSDTGLNRTTVTTITV 318
           LFIP IT  +SG Y C   NS TG   +   T+ V
Sbjct: 379 LFIPQITTKHSGLYACSVRNSATGKESSKSMTVKV 413


>gi|157805480 pregnancy specific beta-1-glycoprotein 7 precursor
           [Homo sapiens]
          Length = 419

 Score =  293 bits (750), Expect = 4e-79
 Identities = 171/404 (42%), Positives = 228/404 (56%), Gaps = 21/404 (5%)

Query: 5   SAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQHLFG 64
           SAPP    I W+ LLLTASLL FWNPPTTA++TIE+ P  V+EGK+VLLLVHNLPQ+L G
Sbjct: 5   SAPPCTQHITWKGLLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQNLTG 64

Query: 65  YSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFYTLHV 124
           Y WYKG+  D    +  Y++  Q    GPAYSGRE +Y NASLLIQN+ Q DTG YTLH+
Sbjct: 65  YIWYKGQIRDLYHYVTSYIVDGQIIKYGPAYSGRETVYSNASLLIQNVTQEDTGSYTLHI 124

Query: 125 IKSDLVNEEATGQ--FRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNN 182
           IK        TG+  F +Y E PKPSISS+N  P E  +AV  TC+PET DA+YLWW+N 
Sbjct: 125 IKRGDGTGGVTGRFTFTLYLETPKPSISSSNFNPREATEAVILTCDPETPDASYLWWMNG 184

Query: 183 QSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTI 242
           QSLP++  LQLS  NRTL LF VT      Y+CE +NPVSA RSD V LN+L     P I
Sbjct: 185 QSLPMTHSLQLSETNRTLYLFGVTNYTAGPYECEIRNPVSASRSDPVTLNLLPKLPKPYI 244

Query: 243 SPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTF---------QQSTQELFIPNITVNN 293
           +  N + R  ++++       +    Y W++NG           +   + L +P++T N 
Sbjct: 245 TINNLNPRENKDVSTFTCEPKSENYTYIWWLNGQSLPVSPRVKRRIENRILILPSVTRNE 304

Query: 294 SGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTT 353
           +G Y C+  +   G+    VT   +Y  P  P I  + +     ++              
Sbjct: 305 TGPYQCEIRDRYGGIRSDPVTLNVLYG-PDLPRIYPSFTYYHSGQNLYLSCFADSNPPAQ 363

Query: 354 YLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQN 397
           Y W +N        + QLS   + L++  +T    G Y C ++N
Sbjct: 364 YSWTING-------KFQLS--GQKLSIPQITTKHSGLYACSVRN 398



 Score =  236 bits (603), Expect = 4e-62
 Identities = 148/411 (36%), Positives = 211/411 (51%), Gaps = 40/411 (9%)

Query: 121 TLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWW- 179
           T H+    L+   +   F   P   + +I +   K  E KD +            Y+W+ 
Sbjct: 10  TQHITWKGLLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQNLTGYIWYK 69

Query: 180 --------------VNNQSLPVSPRL---QLSNGNRTLTLFNVTRNDTASY------KCE 216
                         V+ Q +   P     +    N +L + NVT+ DT SY      + +
Sbjct: 70  GQIRDLYHYVTSYIVDGQIIKYGPAYSGRETVYSNASLLIQNVTQEDTGSYTLHIIKRGD 129

Query: 217 TQNPVSARRSDSVILNVLYGPDAPTISPLNTSYRSG-ENLNLSCHAASNPPAQYSWFVNG 275
               V+ R + ++ L        P+IS  N + R   E + L+C   + P A Y W++NG
Sbjct: 130 GTGGVTGRFTFTLYLET----PKPSISSSNFNPREATEAVILTCDPET-PDASYLWWMNG 184

Query: 276 T---------FQQSTQELFIPNITVNNSGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPF 326
                       ++ + L++  +T   +G Y C+  N     +R+   T+ +  + PKP+
Sbjct: 185 QSLPMTHSLQLSETNRTLYLFGVTNYTAGPYECEIRNP-VSASRSDPVTLNLLPKLPKPY 243

Query: 327 ITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRN 386
           IT NN NP E++D    TCEP+ +N TY+WW+N QSLPVSPR++   +NR L L SVTRN
Sbjct: 244 ITINNLNPRENKDVSTFTCEPKSENYTYIWWLNGQSLPVSPRVKRRIENRILILPSVTRN 303

Query: 387 DVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTISPSYTYYRPGVNLSLSCHAASNPPAQ 446
           + GPY+C I+++     SDPV LNVLYGPD P I PS+TYY  G NL LSC A SNPPAQ
Sbjct: 304 ETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPRIYPSFTYYHSGQNLYLSCFADSNPPAQ 363

Query: 447 YSWLIDGNIQQHTQELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVS 497
           YSW I+G  Q   Q+L I  IT K+SGLY C   NSA+G   +   T+ VS
Sbjct: 364 YSWTINGKFQLSGQKLSIPQITTKHSGLYACSVRNSATGKESSKSVTVRVS 414



 Score =  214 bits (545), Expect = 2e-55
 Identities = 143/400 (35%), Positives = 198/400 (49%), Gaps = 45/400 (11%)

Query: 309 NRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWW----------- 357
           N  T   +T+ A+PPK           E +D + L        T Y+W+           
Sbjct: 29  NPPTTAQVTIEAQPPKVS---------EGKDVLLLVHNLPQNLTGYIWYKGQIRDLYHYV 79

Query: 358 ----VNNQSLPVSPRL---QLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVI-- 408
               V+ Q +   P     +    N +L + +VT+ D G Y   I  +   D +  V   
Sbjct: 80  TSYIVDGQIIKYGPAYSGRETVYSNASLLIQNVTQEDTGSYTLHIIKR--GDGTGGVTGR 137

Query: 409 --LNVLYGPDDPTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGN---------IQQ 457
               +      P+IS S    R      +       P A Y W ++G          + +
Sbjct: 138 FTFTLYLETPKPSISSSNFNPREATEAVILTCDPETPDASYLWWMNGQSLPMTHSLQLSE 197

Query: 458 HTQELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKD 517
             + L++  +T   +G Y C+  N  S  SR+   T+ +  +LPKP I+ NN  P E+KD
Sbjct: 198 TNRTLYLFGVTNYTAGPYECEIRNPVSA-SRSDPVTLNLLPKLPKPYITINNLNPRENKD 256

Query: 518 AVAFTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSV 577
              FTCEP+++N TY+WW+NGQSLPVSPR++    NR L L +VTRN+   Y C I++  
Sbjct: 257 VSTFTCEPKSENYTYIWWLNGQSLPVSPRVKRRIENRILILPSVTRNETGPYQCEIRDRY 316

Query: 578 SANRSDPVTLDVLYGPDTPIISPPDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHT 637
              RSDPVTL+VLYGPD P I P  + Y SG NL LSC + SNP  QYSW ING  Q   
Sbjct: 317 GGIRSDPVTLNVLYGPDLPRIYPSFTYYHSGQNLYLSCFADSNPPAQYSWTINGKFQLSG 376

Query: 638 QVLFIAKITPNNNGTYACFVSNLATGRNNSIVKSITVSAS 677
           Q L I +IT  ++G YAC V N ATG+ +S  KS+TV  S
Sbjct: 377 QKLSIPQITTKHSGLYACSVRNSATGKESS--KSVTVRVS 414



 Score =  203 bits (516), Expect = 5e-52
 Identities = 115/286 (40%), Positives = 152/286 (53%), Gaps = 18/286 (6%)

Query: 33  TAKLTIESTPFNVAEGKEVLLLVHNLPQHLFGYSWYKGERVDGNRQIIGYVIGTQQATPG 92
           T K +I S+ FN  E  E ++L  +       Y W+       N Q +            
Sbjct: 146 TPKPSISSSNFNPREATEAVILTCDPETPDASYLWWM------NGQSL------------ 187

Query: 93  PAYSGREIIYPNASLLIQNIIQNDTGFYTLHVIKSDLVNEEATGQFRVYPELPKPSISSN 152
           P     ++   N +L +  +     G Y   +      +        + P+LPKP I+ N
Sbjct: 188 PMTHSLQLSETNRTLYLFGVTNYTAGPYECEIRNPVSASRSDPVTLNLLPKLPKPYITIN 247

Query: 153 NSKPVEDKDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTLFNVTRNDTAS 212
           N  P E+KD   FTCEP++++ TY+WW+N QSLPVSPR++    NR L L +VTRN+T  
Sbjct: 248 NLNPRENKDVSTFTCEPKSENYTYIWWLNGQSLPVSPRVKRRIENRILILPSVTRNETGP 307

Query: 213 YKCETQNPVSARRSDSVILNVLYGPDAPTISPLNTSYRSGENLNLSCHAASNPPAQYSWF 272
           Y+CE ++     RSD V LNVLYGPD P I P  T Y SG+NL LSC A SNPPAQYSW 
Sbjct: 308 YQCEIRDRYGGIRSDPVTLNVLYGPDLPRIYPSFTYYHSGQNLYLSCFADSNPPAQYSWT 367

Query: 273 VNGTFQQSTQELFIPNITVNNSGSYTCQAHNSDTGLNRTTVTTITV 318
           +NG FQ S Q+L IP IT  +SG Y C   NS TG   +   T+ V
Sbjct: 368 INGKFQLSGQKLSIPQITTKHSGLYACSVRNSATGKESSKSVTVRV 413


>gi|156616284 pregnancy specific beta-1-glycoprotein 9 [Homo
           sapiens]
          Length = 426

 Score =  288 bits (736), Expect = 2e-77
 Identities = 176/405 (43%), Positives = 227/405 (56%), Gaps = 25/405 (6%)

Query: 6   APPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQHLFGY 65
           AP     I W+ LLLTASLL FWNPPTTA++TIE+ P  V+EGK+VLLLVHNLPQ+L GY
Sbjct: 6   APSCTQRITWKGLLLTASLLNFWNPPTTAEVTIEAQPPKVSEGKDVLLLVHNLPQNLPGY 65

Query: 66  SWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFYTLHVI 125
            WYKGE  D    II Y++  +    GPAYSGRE +Y NASLLIQN+ + D G YTLH+I
Sbjct: 66  FWYKGEMTDLYHYIISYIVDGKIIIYGPAYSGRETVYSNASLLIQNVTRKDAGTYTLHII 125

Query: 126 K-SDLVNEEATG-QFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNNQ 183
           K  D   EE     F +Y E PKP ISS+N  P E  +AV   C+PET DA+YLWW+N Q
Sbjct: 126 KRGDETREEIRHFTFTLYLETPKPYISSSNLNPREAMEAVRLICDPETLDASYLWWMNGQ 185

Query: 184 SLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTIS 243
           SLPV+ RLQLS  NRTL LF VT+     Y+CE +NPVSA RSD V LN+L     P I+
Sbjct: 186 SLPVTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLPIPYIT 245

Query: 244 PLNTSYRSGEN-LNLSCHAASNPPAQYSWFVNGTFQQ---------STQELFIPNITVNN 293
             N + R  ++ L  +C   S     Y W++NG               + L +P++T N 
Sbjct: 246 INNLNPRENKDVLAFTCEPKSE-NYTYIWWLNGQSLPVSPGVKRPIENRILILPSVTRNE 304

Query: 294 SGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQ-NT 352
           +G Y C+  +   GL    V    +Y  P  P I  + +     E+ + L+C  E     
Sbjct: 305 TGPYQCEIRDRYGGLRSNPVILNVLYG-PDLPRIYPSFTYYRSGEN-LDLSCFTESNPPA 362

Query: 353 TYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQN 397
            Y W +N          +     + L +  +TRN  G Y C + N
Sbjct: 363 EYFWTING---------KFQQSGQKLFIPQITRNHSGLYACSVHN 398



 Score =  227 bits (579), Expect = 2e-59
 Identities = 127/313 (40%), Positives = 176/313 (56%), Gaps = 14/313 (4%)

Query: 197 NRTLTLFNVTRNDTASYKCETQNPVSARRSD--SVILNVLYGPDAPTISPLNTSYRSG-E 253
           N +L + NVTR D  +Y           R +       +      P IS  N + R   E
Sbjct: 104 NASLLIQNVTRKDAGTYTLHIIKRGDETREEIRHFTFTLYLETPKPYISSSNLNPREAME 163

Query: 254 NLNLSCHAASNPPAQYSWFVNGT---------FQQSTQELFIPNITVNNSGSYTCQAHNS 304
            + L C   +   A Y W++NG            ++ + L++  +T   +G Y C+  N 
Sbjct: 164 AVRLICDPETLD-ASYLWWMNGQSLPVTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNP 222

Query: 305 DTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQSLP 364
               +R+   T+ +  + P P+IT NN NP E++D +A TCEP+ +N TY+WW+N QSLP
Sbjct: 223 -VSASRSDPVTLNLLPKLPIPYITINNLNPRENKDVLAFTCEPKSENYTYIWWLNGQSLP 281

Query: 365 VSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTISPSY 424
           VSP ++   +NR L L SVTRN+ GPY+C I+++     S+PVILNVLYGPD P I PS+
Sbjct: 282 VSPGVKRPIENRILILPSVTRNETGPYQCEIRDRYGGLRSNPVILNVLYGPDLPRIYPSF 341

Query: 425 TYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTCQANNSAS 484
           TYYR G NL LSC   SNPPA+Y W I+G  QQ  Q+LFI  IT  +SGLY C  +NSA+
Sbjct: 342 TYYRSGENLDLSCFTESNPPAEYFWTINGKFQQSGQKLFIPQITRNHSGLYACSVHNSAT 401

Query: 485 GHSRTTVKTITVS 497
           G   +   T+ VS
Sbjct: 402 GKEISKSMTVKVS 414



 Score =  206 bits (525), Expect = 5e-53
 Identities = 140/407 (34%), Positives = 195/407 (47%), Gaps = 49/407 (12%)

Query: 309 NRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQSL----- 363
           N  T   +T+ A+PPK          V +   V L      QN    +W   +       
Sbjct: 29  NPPTTAEVTIEAQPPK----------VSEGKDVLLLVHNLPQNLPGYFWYKGEMTDLYHY 78

Query: 364 --------------PVSPRLQLSNDNRTLTLLSVTRNDVGPYEC-----GIQNKLSVDHS 404
                         P     +    N +L + +VTR D G Y       G + +  + H 
Sbjct: 79  IISYIVDGKIIIYGPAYSGRETVYSNASLLIQNVTRKDAGTYTLHIIKRGDETREEIRH- 137

Query: 405 DPVILNVLYGPDDPTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGN---------I 455
                 +      P IS S    R  +             A Y W ++G          +
Sbjct: 138 --FTFTLYLETPKPYISSSNLNPREAMEAVRLICDPETLDASYLWWMNGQSLPVTHRLQL 195

Query: 456 QQHTQELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVED 515
            +  + L++  +T+  +G Y C+  N  S  SR+   T+ +  +LP P I+ NN  P E+
Sbjct: 196 SKTNRTLYLFGVTKYIAGPYECEIRNPVSA-SRSDPVTLNLLPKLPIPYITINNLNPREN 254

Query: 516 KDAVAFTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQN 575
           KD +AFTCEP+++N TY+WW+NGQSLPVSP ++    NR L L +VTRN+   Y C I++
Sbjct: 255 KDVLAFTCEPKSENYTYIWWLNGQSLPVSPGVKRPIENRILILPSVTRNETGPYQCEIRD 314

Query: 576 SVSANRSDPVTLDVLYGPDTPIISPPDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQ 635
                RS+PV L+VLYGPD P I P  + Y SG NL+LSC + SNP  +Y W ING  QQ
Sbjct: 315 RYGGLRSNPVILNVLYGPDLPRIYPSFTYYRSGENLDLSCFTESNPPAEYFWTINGKFQQ 374

Query: 636 HTQVLFIAKITPNNNGTYACFVSNLATGRNNSIVKSITVSASGTSPG 682
             Q LFI +IT N++G YAC V N ATG+   I KS+TV  SG   G
Sbjct: 375 SGQKLFIPQITRNHSGLYACSVHNSATGK--EISKSMTVKVSGPCHG 419



 Score =  204 bits (520), Expect = 2e-52
 Identities = 103/215 (47%), Positives = 135/215 (62%)

Query: 104 NASLLIQNIIQNDTGFYTLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAV 163
           N +L +  + +   G Y   +      +        + P+LP P I+ NN  P E+KD +
Sbjct: 199 NRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLPIPYITINNLNPRENKDVL 258

Query: 164 AFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSA 223
           AFTCEP++++ TY+WW+N QSLPVSP ++    NR L L +VTRN+T  Y+CE ++    
Sbjct: 259 AFTCEPKSENYTYIWWLNGQSLPVSPGVKRPIENRILILPSVTRNETGPYQCEIRDRYGG 318

Query: 224 RRSDSVILNVLYGPDAPTISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQE 283
            RS+ VILNVLYGPD P I P  T YRSGENL+LSC   SNPPA+Y W +NG FQQS Q+
Sbjct: 319 LRSNPVILNVLYGPDLPRIYPSFTYYRSGENLDLSCFTESNPPAEYFWTINGKFQQSGQK 378

Query: 284 LFIPNITVNNSGSYTCQAHNSDTGLNRTTVTTITV 318
           LFIP IT N+SG Y C  HNS TG   +   T+ V
Sbjct: 379 LFIPQITRNHSGLYACSVHNSATGKEISKSMTVKV 413



 Score = 32.3 bits (72), Expect = 1.5
 Identities = 28/136 (20%), Positives = 50/136 (36%), Gaps = 13/136 (9%)

Query: 104 NASLLIQNIIQNDTGFYTLHVIK--SDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKD 161
           N  L++ ++ +N+TG Y   +      L +          P+LP+   S    +  E+ D
Sbjct: 292 NRILILPSVTRNETGPYQCEIRDRYGGLRSNPVILNVLYGPDLPRIYPSFTYYRSGENLD 351

Query: 162 AVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPV 221
              FT       A Y W +N +              + L +  +TRN +  Y C   N  
Sbjct: 352 LSCFT--ESNPPAEYFWTINGK---------FQQSGQKLFIPQITRNHSGLYACSVHNSA 400

Query: 222 SARRSDSVILNVLYGP 237
           + +     +   + GP
Sbjct: 401 TGKEISKSMTVKVSGP 416


>gi|109240546 pregnancy specific beta-1-glycoprotein 3 [Homo
           sapiens]
          Length = 428

 Score =  287 bits (735), Expect = 2e-77
 Identities = 179/441 (40%), Positives = 241/441 (54%), Gaps = 32/441 (7%)

Query: 5   SAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQHLFG 64
           SAPP    I W+ LLLTA LL FWN PTTA++TIE+ P  V++GK+VLLLVHNLPQ+L G
Sbjct: 5   SAPPCTQRITWKGLLLTALLLNFWNLPTTAQVTIEAEPTKVSKGKDVLLLVHNLPQNLAG 64

Query: 65  YSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFYTLHV 124
           Y WYKG+  D    I  YV+  Q    GPAYSGRE +Y NASLLIQN+ + D G YTLH+
Sbjct: 65  YIWYKGQMKDLYHYITSYVVDGQIIIYGPAYSGRETVYSNASLLIQNVTREDAGSYTLHI 124

Query: 125 IKSDLVNEEATGQ--FRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNN 182
           +K        TG   F +Y E PKPSISS+N  P ED +AV+ TC+PET DA+YLWW+N 
Sbjct: 125 VKRGDGTRGETGHFTFTLYLETPKPSISSSNLYPREDMEAVSLTCDPETPDASYLWWMNG 184

Query: 183 QSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTI 242
           QSLP++  LQLS   RTL LF VT+     Y+CE +NPVSA RSD V LN+L     P I
Sbjct: 185 QSLPMTHSLQLSKNKRTLFLFGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLPKPYI 244

Query: 243 SPLNTSYRSGEN-LNLSCHAASNPPAQYSWFVNGTFQQ---------STQELFIPNITVN 292
           +  N + R  ++ L  +C   S     Y W++NG               + L +P++T N
Sbjct: 245 TINNLNPRENKDVLAFTCEPKSE-NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRN 303

Query: 293 NSGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNT 352
            +G Y C+  +   G+    VT   +Y  P  P I  + +     E+             
Sbjct: 304 ETGPYQCEIQDRYGGIRSYPVTLNVLYG-PDLPRIYPSFTYYHSGENLYLSCFADSNPPA 362

Query: 353 TYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLS-VDHSDPVILNV 411
            Y W +N        + QLS   + L +  +T    G Y C ++N  + ++ S  + + V
Sbjct: 363 EYSWTING-------KFQLS--GQKLFIPQITTKHSGLYACSVRNSATGMESSKSMTVKV 413

Query: 412 LYGPDDPTISPSYTYYRPGVN 432
                    +PS T + PG+N
Sbjct: 414 --------SAPSGTGHLPGLN 426



 Score =  242 bits (618), Expect = 7e-64
 Identities = 134/314 (42%), Positives = 181/314 (57%), Gaps = 14/314 (4%)

Query: 197 NRTLTLFNVTRNDTASYKCETQNPVSARRSDS--VILNVLYGPDAPTISPLNTSYRSG-E 253
           N +L + NVTR D  SY           R ++      +      P+IS  N   R   E
Sbjct: 104 NASLLIQNVTREDAGSYTLHIVKRGDGTRGETGHFTFTLYLETPKPSISSSNLYPREDME 163

Query: 254 NLNLSCHAASNPPAQYSWFVNGT---------FQQSTQELFIPNITVNNSGSYTCQAHNS 304
            ++L+C   + P A Y W++NG            ++ + LF+  +T   +G Y C+  N 
Sbjct: 164 AVSLTCDPET-PDASYLWWMNGQSLPMTHSLQLSKNKRTLFLFGVTKYTAGPYECEIRNP 222

Query: 305 DTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQSLP 364
               +R+   T+ +  + PKP+IT NN NP E++D +A TCEP+ +N TY+WW+N QSLP
Sbjct: 223 -VSASRSDPVTLNLLPKLPKPYITINNLNPRENKDVLAFTCEPKSENYTYIWWLNGQSLP 281

Query: 365 VSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTISPSY 424
           VSPR++   +NR L L SVTRN+ GPY+C IQ++     S PV LNVLYGPD P I PS+
Sbjct: 282 VSPRVKRPIENRILILPSVTRNETGPYQCEIQDRYGGIRSYPVTLNVLYGPDLPRIYPSF 341

Query: 425 TYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTCQANNSAS 484
           TYY  G NL LSC A SNPPA+YSW I+G  Q   Q+LFI  IT K+SGLY C   NSA+
Sbjct: 342 TYYHSGENLYLSCFADSNPPAEYSWTINGKFQLSGQKLFIPQITTKHSGLYACSVRNSAT 401

Query: 485 GHSRTTVKTITVSA 498
           G   +   T+ VSA
Sbjct: 402 GMESSKSMTVKVSA 415



 Score =  223 bits (568), Expect = 5e-58
 Identities = 136/325 (41%), Positives = 186/325 (57%), Gaps = 17/325 (5%)

Query: 375 NRTLTLLSVTRNDVGPYECGIQNKLSVDHSDP--VILNVLYGPDDPTISPSYTYYRPGVN 432
           N +L + +VTR D G Y   I  +      +       +      P+IS S  Y R  + 
Sbjct: 104 NASLLIQNVTREDAGSYTLHIVKRGDGTRGETGHFTFTLYLETPKPSISSSNLYPREDME 163

Query: 433 -LSLSCHAASNPPAQYSWLIDGN---------IQQHTQELFISNITEKNSGLYTCQANNS 482
            +SL+C   + P A Y W ++G          + ++ + LF+  +T+  +G Y C+  N 
Sbjct: 164 AVSLTCDPET-PDASYLWWMNGQSLPMTHSLQLSKNKRTLFLFGVTKYTAGPYECEIRNP 222

Query: 483 ASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQSLP 542
            S  SR+   T+ +  +LPKP I+ NN  P E+KD +AFTCEP+++N TY+WW+NGQSLP
Sbjct: 223 VSA-SRSDPVTLNLLPKLPKPYITINNLNPRENKDVLAFTCEPKSENYTYIWWLNGQSLP 281

Query: 543 VSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISPPD 602
           VSPR++    NR L L +VTRN+   Y C IQ+     RS PVTL+VLYGPD P I P  
Sbjct: 282 VSPRVKRPIENRILILPSVTRNETGPYQCEIQDRYGGIRSYPVTLNVLYGPDLPRIYPSF 341

Query: 603 SSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQVLFIAKITPNNNGTYACFVSNLAT 662
           + Y SG NL LSC + SNP  +YSW ING  Q   Q LFI +IT  ++G YAC V N AT
Sbjct: 342 TYYHSGENLYLSCFADSNPPAEYSWTINGKFQLSGQKLFIPQITTKHSGLYACSVRNSAT 401

Query: 663 GRNNSIVKSITVSA-SGTS--PGLS 684
           G  +S   ++ VSA SGT   PGL+
Sbjct: 402 GMESSKSMTVKVSAPSGTGHLPGLN 426


>gi|21361392 pregnancy specific beta-1-glycoprotein 1 [Homo sapiens]
          Length = 426

 Score =  286 bits (732), Expect = 5e-77
 Identities = 170/409 (41%), Positives = 229/409 (55%), Gaps = 23/409 (5%)

Query: 1   MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ 60
           M + SAPP    I W+ LLLTASLL FWN PTTA++TIE+ P  V+EGK+VLLLVHNLPQ
Sbjct: 1   MGTLSAPPCTQRIKWKGLLLTASLLNFWNLPTTAQVTIEAEPTKVSEGKDVLLLVHNLPQ 60

Query: 61  HLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFY 120
           +L GY WYKG+  D    I  YV+  +    GPAYSGRE  Y NASLLIQN+ + D G Y
Sbjct: 61  NLTGYIWYKGQMRDLYHYITSYVVDGEIIIYGPAYSGRETAYSNASLLIQNVTREDAGSY 120

Query: 121 TLHVIKSDLVNEEATGQ--FRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLW 178
           TLH+IK D      TG+  F ++ E PKPSISS+N  P E  +AV+ TC+PET DA+YLW
Sbjct: 121 TLHIIKGDDGTRGVTGRFTFTLHLETPKPSISSSNLNPRETMEAVSLTCDPETPDASYLW 180

Query: 179 WVNNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPD 238
           W+N QSLP++  L+LS  NRTL L  VT+     Y+CE +NPVSA RSD V LN+L    
Sbjct: 181 WMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLP 240

Query: 239 APTISPLNTSYRSGEN-LNLSCHAASNPPAQYSWFVNGTFQQ---------STQELFIPN 288
            P I+  N + R  ++ LN +C   S     Y W++NG               + L +P+
Sbjct: 241 KPYITINNLNPRENKDVLNFTCEPKSE-NYTYIWWLNGQSLPVSPRVKRPIENRILILPS 299

Query: 289 ITVNNSGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPE 348
           +T N +G Y C+  +   G+    VT   +Y  P  P I  + +      + + L+C  +
Sbjct: 300 VTRNETGPYQCEIRDRYGGIRSDPVTLNVLYG-PDLPRIYPSFTY-YRSGEVLYLSCSAD 357

Query: 349 IQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQN 397
                   W  N+   +          + L +  +T    G Y C ++N
Sbjct: 358 SNPPAQYSWTINEKFQL--------PGQKLFIRHITTKHSGLYVCSVRN 398



 Score =  237 bits (604), Expect = 3e-62
 Identities = 132/315 (41%), Positives = 181/315 (57%), Gaps = 14/315 (4%)

Query: 197 NRTLTLFNVTRNDTASYKCETQNPVSARR--SDSVILNVLYGPDAPTISPLNTSYRSG-E 253
           N +L + NVTR D  SY           R  +      +      P+IS  N + R   E
Sbjct: 104 NASLLIQNVTREDAGSYTLHIIKGDDGTRGVTGRFTFTLHLETPKPSISSSNLNPRETME 163

Query: 254 NLNLSCHAASNPPAQYSWFVNGT---------FQQSTQELFIPNITVNNSGSYTCQAHNS 304
            ++L+C   + P A Y W++NG            ++ + LF+  +T   +G Y C+  N 
Sbjct: 164 AVSLTCDPET-PDASYLWWMNGQSLPMTHSLKLSETNRTLFLLGVTKYTAGPYECEIRNP 222

Query: 305 DTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQSLP 364
               +R+   T+ +  + PKP+IT NN NP E++D +  TCEP+ +N TY+WW+N QSLP
Sbjct: 223 -VSASRSDPVTLNLLPKLPKPYITINNLNPRENKDVLNFTCEPKSENYTYIWWLNGQSLP 281

Query: 365 VSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTISPSY 424
           VSPR++   +NR L L SVTRN+ GPY+C I+++     SDPV LNVLYGPD P I PS+
Sbjct: 282 VSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSDPVTLNVLYGPDLPRIYPSF 341

Query: 425 TYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTCQANNSAS 484
           TYYR G  L LSC A SNPPAQYSW I+   Q   Q+LFI +IT K+SGLY C   NSA+
Sbjct: 342 TYYRSGEVLYLSCSADSNPPAQYSWTINEKFQLPGQKLFIRHITTKHSGLYVCSVRNSAT 401

Query: 485 GHSRTTVKTITVSAE 499
           G   +   T+ VS +
Sbjct: 402 GKESSKSMTVEVSGK 416



 Score =  211 bits (538), Expect = 1e-54
 Identities = 146/402 (36%), Positives = 203/402 (50%), Gaps = 47/402 (11%)

Query: 309 NRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWW----------- 357
           N  T   +T+ AEP K           E +D + L        T Y+W+           
Sbjct: 29  NLPTTAQVTIEAEPTKVS---------EGKDVLLLVHNLPQNLTGYIWYKGQMRDLYHYI 79

Query: 358 ----VNNQSLPVSPRL---QLSNDNRTLTLLSVTRNDVGPYEC----GIQNKLSVDHSDP 406
               V+ + +   P     + +  N +L + +VTR D G Y      G      V     
Sbjct: 80  TSYVVDGEIIIYGPAYSGRETAYSNASLLIQNVTREDAGSYTLHIIKGDDGTRGVTGRFT 139

Query: 407 VILNVLYGPDDPTISPSYTYYRPGVN-LSLSCHAASNPPAQYSWLIDGN---------IQ 456
             L++      P+IS S    R  +  +SL+C   + P A Y W ++G          + 
Sbjct: 140 FTLHL--ETPKPSISSSNLNPRETMEAVSLTCDPET-PDASYLWWMNGQSLPMTHSLKLS 196

Query: 457 QHTQELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDK 516
           +  + LF+  +T+  +G Y C+  N  S  SR+   T+ +  +LPKP I+ NN  P E+K
Sbjct: 197 ETNRTLFLLGVTKYTAGPYECEIRNPVSA-SRSDPVTLNLLPKLPKPYITINNLNPRENK 255

Query: 517 DAVAFTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNS 576
           D + FTCEP+++N TY+WW+NGQSLPVSPR++    NR L L +VTRN+   Y C I++ 
Sbjct: 256 DVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDR 315

Query: 577 VSANRSDPVTLDVLYGPDTPIISPPDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQH 636
               RSDPVTL+VLYGPD P I P  + Y SG  L LSC + SNP  QYSW IN   Q  
Sbjct: 316 YGGIRSDPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNPPAQYSWTINEKFQLP 375

Query: 637 TQVLFIAKITPNNNGTYACFVSNLATGRNNSIVKSITVSASG 678
            Q LFI  IT  ++G Y C V N ATG+ +S  KS+TV  SG
Sbjct: 376 GQKLFIRHITTKHSGLYVCSVRNSATGKESS--KSMTVEVSG 415



 Score =  195 bits (495), Expect = 1e-49
 Identities = 100/215 (46%), Positives = 130/215 (60%)

Query: 104 NASLLIQNIIQNDTGFYTLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAV 163
           N +L +  + +   G Y   +      +        + P+LPKP I+ NN  P E+KD +
Sbjct: 199 NRTLFLLGVTKYTAGPYECEIRNPVSASRSDPVTLNLLPKLPKPYITINNLNPRENKDVL 258

Query: 164 AFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSA 223
            FTCEP++++ TY+WW+N QSLPVSPR++    NR L L +VTRN+T  Y+CE ++    
Sbjct: 259 NFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGG 318

Query: 224 RRSDSVILNVLYGPDAPTISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQE 283
            RSD V LNVLYGPD P I P  T YRSGE L LSC A SNPPAQYSW +N  FQ   Q+
Sbjct: 319 IRSDPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNPPAQYSWTINEKFQLPGQK 378

Query: 284 LFIPNITVNNSGSYTCQAHNSDTGLNRTTVTTITV 318
           LFI +IT  +SG Y C   NS TG   +   T+ V
Sbjct: 379 LFIRHITTKHSGLYVCSVRNSATGKESSKSMTVEV 413


>gi|42560235 pregnancy specific beta-1-glycoprotein 4 isoform 1
           [Homo sapiens]
          Length = 419

 Score =  286 bits (732), Expect = 5e-77
 Identities = 176/417 (42%), Positives = 233/417 (55%), Gaps = 25/417 (5%)

Query: 5   SAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQHLFG 64
           SAPP    I W+ +LLTASLL FWNPPTTA++TIE+ P  V+EGK+VLLLVHNLPQ+L G
Sbjct: 5   SAPPCTQRITWKGVLLTASLLNFWNPPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQNLAG 64

Query: 65  YSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFYTLHV 124
           Y WYKG+       I  YV+  Q+   GPAYSGRE +Y NASLLIQN+ Q D G YTLH+
Sbjct: 65  YIWYKGQMTYLYHYITSYVVDGQRIIYGPAYSGRERVYSNASLLIQNVTQEDAGSYTLHI 124

Query: 125 IKSDLVNEEATGQ--FRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNN 182
           IK        TG   F ++ E PKPSISS+N  P E  +AV  TC+P T  A+Y WW+N 
Sbjct: 125 IKRRDGTGGVTGHFTFTLHLETPKPSISSSNLNPREAMEAVILTCDPATPAASYQWWMNG 184

Query: 183 QSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTI 242
           QSLP++ RLQLS  NRTL +F VT+     Y+CE +NPVSA RSD V LN+L     P I
Sbjct: 185 QSLPMTHRLQLSKTNRTLFIFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLSKPYI 244

Query: 243 SPLNTSYRSGEN-LNLSCHAASNPPAQYSWFVNGTFQQ---------STQELFIPNITVN 292
           +  N + R  ++ L  +C   S     Y W++NG               + L +PN+T N
Sbjct: 245 TINNLNPRENKDVLTFTCEPKSK-NYTYIWWLNGQSLPVSPRVKRPIENRILILPNVTRN 303

Query: 293 NSGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQ-N 351
            +G Y C+  +   G+    VT   +Y  P  P I  + +     E+ + L+C  E    
Sbjct: 304 ETGPYQCEIRDRYGGIRSDPVTLNVLYG-PDLPSIYPSFTYYRSGEN-LYLSCFAESNPR 361

Query: 352 TTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVI 408
             Y W +N        + QLS   + L++  +T    G Y C ++N  +   S   I
Sbjct: 362 AQYSWTING-------KFQLS--GQKLSIPQITTKHSGLYACSVRNSATGKESSKSI 409



 Score =  232 bits (592), Expect = 8e-61
 Identities = 144/389 (37%), Positives = 203/389 (52%), Gaps = 38/389 (9%)

Query: 142 PELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWW---------------VNNQSLP 186
           P   + +I +   K  E KD +          A Y+W+               V+ Q + 
Sbjct: 31  PTTAQVTIEAQPPKVSEGKDVLLLVHNLPQNLAGYIWYKGQMTYLYHYITSYVVDGQRII 90

Query: 187 VSPRL---QLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVI-----LNVLYGPD 238
             P     +    N +L + NVT+ D  SY   T + +  R     +       +     
Sbjct: 91  YGPAYSGRERVYSNASLLIQNVTQEDAGSY---TLHIIKRRDGTGGVTGHFTFTLHLETP 147

Query: 239 APTISPLNTSYRSG-ENLNLSCHAASNPPAQYSWFVNGT---------FQQSTQELFIPN 288
            P+IS  N + R   E + L+C  A+ P A Y W++NG            ++ + LFI  
Sbjct: 148 KPSISSSNLNPREAMEAVILTCDPAT-PAASYQWWMNGQSLPMTHRLQLSKTNRTLFIFG 206

Query: 289 ITVNNSGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPE 348
           +T   +G Y C+  N     +R+   T+ +  +  KP+IT NN NP E++D +  TCEP+
Sbjct: 207 VTKYIAGPYECEIRNP-VSASRSDPVTLNLLPKLSKPYITINNLNPRENKDVLTFTCEPK 265

Query: 349 IQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVI 408
            +N TY+WW+N QSLPVSPR++   +NR L L +VTRN+ GPY+C I+++     SDPV 
Sbjct: 266 SKNYTYIWWLNGQSLPVSPRVKRPIENRILILPNVTRNETGPYQCEIRDRYGGIRSDPVT 325

Query: 409 LNVLYGPDDPTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNIT 468
           LNVLYGPD P+I PS+TYYR G NL LSC A SNP AQYSW I+G  Q   Q+L I  IT
Sbjct: 326 LNVLYGPDLPSIYPSFTYYRSGENLYLSCFAESNPRAQYSWTINGKFQLSGQKLSIPQIT 385

Query: 469 EKNSGLYTCQANNSASGHSRTTVKTITVS 497
            K+SGLY C   NSA+G   +   T+ VS
Sbjct: 386 TKHSGLYACSVRNSATGKESSKSITVKVS 414



 Score =  216 bits (550), Expect = 6e-56
 Identities = 148/401 (36%), Positives = 205/401 (51%), Gaps = 47/401 (11%)

Query: 309 NRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWW----------- 357
           N  T   +T+ A+PPK           E +D + L          Y+W+           
Sbjct: 29  NPPTTAQVTIEAQPPKVS---------EGKDVLLLVHNLPQNLAGYIWYKGQMTYLYHYI 79

Query: 358 ----VNNQSLPVSPRL---QLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILN 410
               V+ Q +   P     +    N +L + +VT+ D G Y   I  +   D +  V  +
Sbjct: 80  TSYVVDGQRIIYGPAYSGRERVYSNASLLIQNVTQEDAGSYTLHIIKRR--DGTGGVTGH 137

Query: 411 VLYG----PDDPTISPSYTYYRPGVN-LSLSCHAASNPPAQYSWLIDGN---------IQ 456
             +        P+IS S    R  +  + L+C  A+ P A Y W ++G          + 
Sbjct: 138 FTFTLHLETPKPSISSSNLNPREAMEAVILTCDPAT-PAASYQWWMNGQSLPMTHRLQLS 196

Query: 457 QHTQELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDK 516
           +  + LFI  +T+  +G Y C+  N  S  SR+   T+ +  +L KP I+ NN  P E+K
Sbjct: 197 KTNRTLFIFGVTKYIAGPYECEIRNPVSA-SRSDPVTLNLLPKLSKPYITINNLNPRENK 255

Query: 517 DAVAFTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNS 576
           D + FTCEP+++N TY+WW+NGQSLPVSPR++    NR L L NVTRN+   Y C I++ 
Sbjct: 256 DVLTFTCEPKSKNYTYIWWLNGQSLPVSPRVKRPIENRILILPNVTRNETGPYQCEIRDR 315

Query: 577 VSANRSDPVTLDVLYGPDTPIISPPDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQH 636
               RSDPVTL+VLYGPD P I P  + Y SG NL LSC + SNP  QYSW ING  Q  
Sbjct: 316 YGGIRSDPVTLNVLYGPDLPSIYPSFTYYRSGENLYLSCFAESNPRAQYSWTINGKFQLS 375

Query: 637 TQVLFIAKITPNNNGTYACFVSNLATGRNNSIVKSITVSAS 677
            Q L I +IT  ++G YAC V N ATG+ +S  KSITV  S
Sbjct: 376 GQKLSIPQITTKHSGLYACSVRNSATGKESS--KSITVKVS 414


>gi|4506175 pregnancy specific beta-1-glycoprotein 6 isoform a [Homo
           sapiens]
          Length = 435

 Score =  282 bits (722), Expect = 7e-76
 Identities = 186/441 (42%), Positives = 240/441 (54%), Gaps = 36/441 (8%)

Query: 5   SAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQHLFG 64
           SAPP    I W+ LLLTASLL FWN PTTA++ IE+ P  V+EGK+VLLLVHNLPQ+L G
Sbjct: 5   SAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQNLTG 64

Query: 65  YSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFYTLHV 124
           Y WYKG+  D    I  YV+  Q    GPAYSGRE +Y NASLLIQN+ Q D G YTLH+
Sbjct: 65  YIWYKGQMTDLYHYITSYVVHGQ-IIYGPAYSGRETVYSNASLLIQNVTQEDAGSYTLHI 123

Query: 125 IKSDLVNEEATGQFRV--YPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNN 182
           IK        TG F V  Y E PKPSISS+N  P E  +AV   C+PET DA+YLW +N 
Sbjct: 124 IKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLWLLNG 183

Query: 183 QSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTI 242
           Q+LP++ RLQLS  NRTL LF VT+     Y+CE +NPVSA RSD V LN+L     P I
Sbjct: 184 QNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLPMPYI 243

Query: 243 SPLNTSYRSGEN-LNLSCHAASNPPAQYSWFVNGTFQQ---------STQELFIPNITVN 292
           +  N + R  ++ L  +C   S     Y W++NG               + L +P++T N
Sbjct: 244 TINNLNPREKKDVLAFTCEPKSR-NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRN 302

Query: 293 NSGSYTCQAHNSDTGLNRTTVTTITVYA-EPPK--PFITSNNSNPVEDEDAVALTCEPEI 349
            +G Y C+  +   G+    VT   +Y  + P+  P  T   S    D    A +  P  
Sbjct: 303 ETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLDLSCFADSNPP-- 360

Query: 350 QNTTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLS-VDHSDPVI 408
               Y W +N        + QLS   + L +  +T N  G Y C ++N  +  + S  +I
Sbjct: 361 --AEYSWTING-------KFQLS--GQKLFIPQITTNHSGLYACSVRNSATGKEISKSMI 409

Query: 409 LNVLYGPDDPTISPSYTYYRP 429
           + V       T SP  TY  P
Sbjct: 410 VKV-----SETASPQVTYAGP 425



 Score =  228 bits (581), Expect = 1e-59
 Identities = 132/322 (40%), Positives = 180/322 (55%), Gaps = 15/322 (4%)

Query: 197 NRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNV-LYGPDA-PTISPLNTSYRSG-E 253
           N +L + NVT+ D  SY              +    V LY     P+IS  N + R   E
Sbjct: 103 NASLLIQNVTQEDAGSYTLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVME 162

Query: 254 NLNLSCHAASNPPAQYSWFVNGT---------FQQSTQELFIPNITVNNSGSYTCQAHNS 304
            + L C   + P A Y W +NG            ++ + L++  +T   +G Y C+  N 
Sbjct: 163 AVRLICDPET-PDASYLWLLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNP 221

Query: 305 DTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQSLP 364
               +R+   T+ +  + P P+IT NN NP E +D +A TCEP+ +N TY+WW+N QSLP
Sbjct: 222 -VSASRSDPVTLNLLPKLPMPYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQSLP 280

Query: 365 VSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTISPSY 424
           VSPR++   +NR L L SVTRN+ GPY+C I+++     S+PV LNVLYGPD P I PS+
Sbjct: 281 VSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSF 340

Query: 425 TYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTCQANNSAS 484
           TYYR G NL LSC A SNPPA+YSW I+G  Q   Q+LFI  IT  +SGLY C   NSA+
Sbjct: 341 TYYRSGENLDLSCFADSNPPAEYSWTINGKFQLSGQKLFIPQITTNHSGLYACSVRNSAT 400

Query: 485 GHSRTTVKTITVSAELPKPSIS 506
           G   +    + VS E   P ++
Sbjct: 401 GKEISKSMIVKVS-ETASPQVT 421



 Score =  212 bits (540), Expect = 8e-55
 Identities = 143/401 (35%), Positives = 202/401 (50%), Gaps = 42/401 (10%)

Query: 309 NRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWW----------- 357
           N  T   + + A+PPK           E +D + L        T Y+W+           
Sbjct: 29  NLPTTAQVIIEAKPPKVS---------EGKDVLLLVHNLPQNLTGYIWYKGQMTDLYHYI 79

Query: 358 ----VNNQSL--PVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNV 411
               V+ Q +  P     +    N +L + +VT+ D G Y   I  +            V
Sbjct: 80  TSYVVHGQIIYGPAYSGRETVYSNASLLIQNVTQEDAGSYTLHIIKRGDGTGGVTGYFTV 139

Query: 412 LYGPDDPTISPSYTYYRPGVNLS---LSCHAASNPPAQYSWLIDGN---------IQQHT 459
               + P  S S +   P   +    L C   + P A Y WL++G          + +  
Sbjct: 140 TLYSETPKPSISSSNLNPREVMEAVRLICDPET-PDASYLWLLNGQNLPMTHRLQLSKTN 198

Query: 460 QELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAV 519
           + L++  +T+  +G Y C+  N  S  SR+   T+ +  +LP P I+ NN  P E KD +
Sbjct: 199 RTLYLFGVTKYIAGPYECEIRNPVSA-SRSDPVTLNLLPKLPMPYITINNLNPREKKDVL 257

Query: 520 AFTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSA 579
           AFTCEP+++N TY+WW+NGQSLPVSPR++    NR L L +VTRN+   Y C I++    
Sbjct: 258 AFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGG 317

Query: 580 NRSDPVTLDVLYGPDTPIISPPDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQV 639
            RS+PVTL+VLYGPD P I P  + Y SG NL+LSC + SNP  +YSW ING  Q   Q 
Sbjct: 318 IRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLDLSCFADSNPPAEYSWTINGKFQLSGQK 377

Query: 640 LFIAKITPNNNGTYACFVSNLATGRNNSIVKSITVSASGTS 680
           LFI +IT N++G YAC V N ATG+   I KS+ V  S T+
Sbjct: 378 LFIPQITTNHSGLYACSVRNSATGK--EISKSMIVKVSETA 416


>gi|73661174 pregnancy specific beta-1-glycoprotein 6 isoform b
           [Homo sapiens]
          Length = 424

 Score =  279 bits (714), Expect = 6e-75
 Identities = 179/426 (42%), Positives = 233/426 (54%), Gaps = 30/426 (7%)

Query: 5   SAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQHLFG 64
           SAPP    I W+ LLLTASLL FWN PTTA++ IE+ P  V+EGK+VLLLVHNLPQ+L G
Sbjct: 5   SAPPCTQHITWKGLLLTASLLNFWNLPTTAQVIIEAKPPKVSEGKDVLLLVHNLPQNLTG 64

Query: 65  YSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFYTLHV 124
           Y WYKG+  D    I  YV+  Q    GPAYSGRE +Y NASLLIQN+ Q D G YTLH+
Sbjct: 65  YIWYKGQMTDLYHYITSYVVHGQ-IIYGPAYSGRETVYSNASLLIQNVTQEDAGSYTLHI 123

Query: 125 IKSDLVNEEATGQFRV--YPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNN 182
           IK        TG F V  Y E PKPSISS+N  P E  +AV   C+PET DA+YLW +N 
Sbjct: 124 IKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVMEAVRLICDPETPDASYLWLLNG 183

Query: 183 QSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTI 242
           Q+LP++ RLQLS  NRTL LF VT+     Y+CE +NPVSA RSD V LN+L     P I
Sbjct: 184 QNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNPVSASRSDPVTLNLLPKLPMPYI 243

Query: 243 SPLNTSYRSGEN-LNLSCHAASNPPAQYSWFVNGTFQQ---------STQELFIPNITVN 292
           +  N + R  ++ L  +C   S     Y W++NG               + L +P++T N
Sbjct: 244 TINNLNPREKKDVLAFTCEPKSR-NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRN 302

Query: 293 NSGSYTCQAHNSDTGLNRTTVTTITVYA-EPPK--PFITSNNSNPVEDEDAVALTCEPEI 349
            +G Y C+  +   G+    VT   +Y  + P+  P  T   S    D    A +  P  
Sbjct: 303 ETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLDLSCFADSNPP-- 360

Query: 350 QNTTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVIL 409
               Y W +N        + QLS   + L +  +T N  G Y C ++N  +       ++
Sbjct: 361 --AEYSWTING-------KFQLS--GQKLFIPQITTNHSGLYACSVRNSATGKEISKSMI 409

Query: 410 NVLYGP 415
             + GP
Sbjct: 410 VKVSGP 415



 Score =  227 bits (579), Expect = 2e-59
 Identities = 130/313 (41%), Positives = 176/313 (56%), Gaps = 14/313 (4%)

Query: 197 NRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNV-LYGPDA-PTISPLNTSYRSG-E 253
           N +L + NVT+ D  SY              +    V LY     P+IS  N + R   E
Sbjct: 103 NASLLIQNVTQEDAGSYTLHIIKRGDGTGGVTGYFTVTLYSETPKPSISSSNLNPREVME 162

Query: 254 NLNLSCHAASNPPAQYSWFVNGT---------FQQSTQELFIPNITVNNSGSYTCQAHNS 304
            + L C   + P A Y W +NG            ++ + L++  +T   +G Y C+  N 
Sbjct: 163 AVRLICDPET-PDASYLWLLNGQNLPMTHRLQLSKTNRTLYLFGVTKYIAGPYECEIRNP 221

Query: 305 DTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQSLP 364
               +R+   T+ +  + P P+IT NN NP E +D +A TCEP+ +N TY+WW+N QSLP
Sbjct: 222 -VSASRSDPVTLNLLPKLPMPYITINNLNPREKKDVLAFTCEPKSRNYTYIWWLNGQSLP 280

Query: 365 VSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTISPSY 424
           VSPR++   +NR L L SVTRN+ GPY+C I+++     S+PV LNVLYGPD P I PS+
Sbjct: 281 VSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGGIRSNPVTLNVLYGPDLPRIYPSF 340

Query: 425 TYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTCQANNSAS 484
           TYYR G NL LSC A SNPPA+YSW I+G  Q   Q+LFI  IT  +SGLY C   NSA+
Sbjct: 341 TYYRSGENLDLSCFADSNPPAEYSWTINGKFQLSGQKLFIPQITTNHSGLYACSVRNSAT 400

Query: 485 GHSRTTVKTITVS 497
           G   +    + VS
Sbjct: 401 GKEISKSMIVKVS 413



 Score =  214 bits (544), Expect = 3e-55
 Identities = 144/403 (35%), Positives = 202/403 (50%), Gaps = 42/403 (10%)

Query: 309 NRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWW----------- 357
           N  T   + + A+PPK           E +D + L        T Y+W+           
Sbjct: 29  NLPTTAQVIIEAKPPKVS---------EGKDVLLLVHNLPQNLTGYIWYKGQMTDLYHYI 79

Query: 358 ----VNNQSL--PVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNV 411
               V+ Q +  P     +    N +L + +VT+ D G Y   I  +            V
Sbjct: 80  TSYVVHGQIIYGPAYSGRETVYSNASLLIQNVTQEDAGSYTLHIIKRGDGTGGVTGYFTV 139

Query: 412 LYGPDDPTISPSYTYYRPGVNLS---LSCHAASNPPAQYSWLIDGN---------IQQHT 459
               + P  S S +   P   +    L C   + P A Y WL++G          + +  
Sbjct: 140 TLYSETPKPSISSSNLNPREVMEAVRLICDPET-PDASYLWLLNGQNLPMTHRLQLSKTN 198

Query: 460 QELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAV 519
           + L++  +T+  +G Y C+  N  S  SR+   T+ +  +LP P I+ NN  P E KD +
Sbjct: 199 RTLYLFGVTKYIAGPYECEIRNPVSA-SRSDPVTLNLLPKLPMPYITINNLNPREKKDVL 257

Query: 520 AFTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSA 579
           AFTCEP+++N TY+WW+NGQSLPVSPR++    NR L L +VTRN+   Y C I++    
Sbjct: 258 AFTCEPKSRNYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDRYGG 317

Query: 580 NRSDPVTLDVLYGPDTPIISPPDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQV 639
            RS+PVTL+VLYGPD P I P  + Y SG NL+LSC + SNP  +YSW ING  Q   Q 
Sbjct: 318 IRSNPVTLNVLYGPDLPRIYPSFTYYRSGENLDLSCFADSNPPAEYSWTINGKFQLSGQK 377

Query: 640 LFIAKITPNNNGTYACFVSNLATGRNNSIVKSITVSASGTSPG 682
           LFI +IT N++G YAC V N ATG+   I KS+ V  SG   G
Sbjct: 378 LFIPQITTNHSGLYACSVRNSATGK--EISKSMIVKVSGPCHG 418


>gi|121114300 carcinoembryonic antigen-related cell adhesion
           molecule 3 precursor [Homo sapiens]
          Length = 252

 Score =  250 bits (638), Expect = 4e-66
 Identities = 122/143 (85%), Positives = 125/143 (87%)

Query: 1   MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ 60
           M  PSA PHR CIPWQ LLLTASLL FWNPPTTAKLTIES P +VAEGKEVLLLVHNLPQ
Sbjct: 1   MGPPSASPHRECIPWQGLLLTASLLNFWNPPTTAKLTIESMPLSVAEGKEVLLLVHNLPQ 60

Query: 61  HLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFY 120
           HLFGYSWYKGERVDGN  I+GYVIGTQQATPG AYSGRE IY NASLLIQN+ QND GFY
Sbjct: 61  HLFGYSWYKGERVDGNSLIVGYVIGTQQATPGAAYSGRETIYTNASLLIQNVTQNDIGFY 120

Query: 121 TLHVIKSDLVNEEATGQFRVYPE 143
           TL VIKSDLVNEEATGQF VY E
Sbjct: 121 TLQVIKSDLVNEEATGQFHVYQE 143



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 25/72 (34%), Positives = 33/72 (45%), Gaps = 20/72 (27%)

Query: 640 LFIAKITPNNNGTYACFVSNLATGRNNSIVKSITVSASGT---------SPGLSAGATVG 690
           L I  +T N+ G Y              ++KS  V+   T         +PGL  GA  G
Sbjct: 107 LLIQNVTQNDIGFYTL-----------QVIKSDLVNEEATGQFHVYQENAPGLPVGAVAG 155

Query: 691 IMIGVLVGVALI 702
           I+ GVLVGVAL+
Sbjct: 156 IVTGVLVGVALV 167


>gi|194328712 pregnancy specific beta-1-glycoprotein 8 isoform c
           [Homo sapiens]
          Length = 297

 Score =  226 bits (575), Expect = 7e-59
 Identities = 120/268 (44%), Positives = 163/268 (60%), Gaps = 12/268 (4%)

Query: 240 PTISPLNTSYRSG-ENLNLSCHAASNPPAQYSWFVNGT---------FQQSTQELFIPNI 289
           P+IS    + R   E ++L+C   + P A Y W++NG            ++ + LF+  +
Sbjct: 27  PSISSSKLNPREAMEAVSLTCDPET-PDASYLWWMNGQSLPMSHRLQLSETNRTLFLLGV 85

Query: 290 TVNNSGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEI 349
           T   +G Y C+  N     +R+   T+ +  + PKP+IT NN  P E++D +  TCEP+ 
Sbjct: 86  TKYTAGPYECEIRNP-VSASRSDPFTLNLLPKLPKPYITINNLKPRENKDVLNFTCEPKS 144

Query: 350 QNTTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVIL 409
           +N TY+WW+N QSLPVSPR++   +NR L L SVTRN+ GPY+C I+++     S PV L
Sbjct: 145 ENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGGIRSYPVTL 204

Query: 410 NVLYGPDDPTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITE 469
           NVLYGPD P I PS+TYYR G  L LSC A SNPPAQYSW I+G  Q   Q+LFI  IT 
Sbjct: 205 NVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNPPAQYSWTINGKFQLSGQKLFIPQITT 264

Query: 470 KNSGLYTCQANNSASGHSRTTVKTITVS 497
           K+SGLY C   NSA+G   +   T+ VS
Sbjct: 265 KHSGLYACSVRNSATGKESSKSMTVKVS 292



 Score =  210 bits (535), Expect = 3e-54
 Identities = 126/314 (40%), Positives = 164/314 (52%), Gaps = 27/314 (8%)

Query: 5   SAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQHLFG 64
           SAPP    I W+ LLLT           T K +I S+  N  E  E + L  +       
Sbjct: 5   SAPPCTQRITWKGLLLTVE---------TPKPSISSSKLNPREAMEAVSLTCDPETPDAS 55

Query: 65  YSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFYTLHV 124
           Y W+       N Q +            P     ++   N +L +  + +   G Y   +
Sbjct: 56  YLWWM------NGQSL------------PMSHRLQLSETNRTLFLLGVTKYTAGPYECEI 97

Query: 125 IKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNNQS 184
                 +        + P+LPKP I+ NN KP E+KD + FTCEP++++ TY+WW+N QS
Sbjct: 98  RNPVSASRSDPFTLNLLPKLPKPYITINNLKPRENKDVLNFTCEPKSENYTYIWWLNGQS 157

Query: 185 LPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTISP 244
           LPVSPR++    NR L L +VTRN+T  Y+CE ++     RS  V LNVLYGPD P I P
Sbjct: 158 LPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGGIRSYPVTLNVLYGPDLPRIYP 217

Query: 245 LNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQAHNS 304
             T YRSGE L LSC A SNPPAQYSW +NG FQ S Q+LFIP IT  +SG Y C   NS
Sbjct: 218 SFTYYRSGEVLYLSCSADSNPPAQYSWTINGKFQLSGQKLFIPQITTKHSGLYACSVRNS 277

Query: 305 DTGLNRTTVTTITV 318
            TG   +   T+ V
Sbjct: 278 ATGKESSKSMTVKV 291



 Score =  209 bits (531), Expect = 9e-54
 Identities = 121/270 (44%), Positives = 163/270 (60%), Gaps = 14/270 (5%)

Query: 418 PTISPSYTYYRPGVN-LSLSCHAASNPPAQYSWLIDGN---------IQQHTQELFISNI 467
           P+IS S    R  +  +SL+C   + P A Y W ++G          + +  + LF+  +
Sbjct: 27  PSISSSKLNPREAMEAVSLTCDPET-PDASYLWWMNGQSLPMSHRLQLSETNRTLFLLGV 85

Query: 468 TEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEA 527
           T+  +G Y C+  N  S  SR+   T+ +  +LPKP I+ NN KP E+KD + FTCEP++
Sbjct: 86  TKYTAGPYECEIRNPVSA-SRSDPFTLNLLPKLPKPYITINNLKPRENKDVLNFTCEPKS 144

Query: 528 QNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTL 587
           +N TY+WW+NGQSLPVSPR++    NR L L +VTRN+   Y C I++     RS PVTL
Sbjct: 145 ENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCEIRDQYGGIRSYPVTL 204

Query: 588 DVLYGPDTPIISPPDSSYLSGANLNLSCHSASNPSPQYSWRINGIPQQHTQVLFIAKITP 647
           +VLYGPD P I P  + Y SG  L LSC + SNP  QYSW ING  Q   Q LFI +IT 
Sbjct: 205 NVLYGPDLPRIYPSFTYYRSGEVLYLSCSADSNPPAQYSWTINGKFQLSGQKLFIPQITT 264

Query: 648 NNNGTYACFVSNLATGRNNSIVKSITVSAS 677
            ++G YAC V N ATG+ +S  KS+TV  S
Sbjct: 265 KHSGLYACSVRNSATGKESS--KSMTVKVS 292



 Score =  132 bits (333), Expect = 8e-31
 Identities = 95/287 (33%), Positives = 138/287 (48%), Gaps = 29/287 (10%)

Query: 310 RTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQSLPVSPRL 369
           R T   + +  E PKP I+S+  NP E  +AV+LTC+PE  + +YLWW+N QSLP+S RL
Sbjct: 12  RITWKGLLLTVETPKPSISSSKLNPREAMEAVSLTCDPETPDASYLWWMNGQSLPMSHRL 71

Query: 370 QLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTISPSYTYYRP 429
           QLS  NRTL LL VT+   GPYEC I+N +S   SDP  LN+L  P  P    +    +P
Sbjct: 72  QLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPFTLNLL--PKLPKPYITINNLKP 129

Query: 430 GVN---LSLSCHAASNPPAQYSWL------IDGNIQQHTQE--LFISNITEKNSGLYTCQ 478
             N   L+ +C   S       WL      +   +++  +   L + ++T   +G Y C+
Sbjct: 130 RENKDVLNFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQCE 189

Query: 479 ANNSASG-HSRTTVKTITVSAELPK--PSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWW 535
             +   G  S      +    +LP+  PS +   S  V      A    P AQ   Y W 
Sbjct: 190 IRDQYGGIRSYPVTLNVLYGPDLPRIYPSFTYYRSGEVLYLSCSA-DSNPPAQ---YSWT 245

Query: 536 VNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRS 582
           +NG       + QLS   + L +  +T   +  Y C ++NS +   S
Sbjct: 246 ING-------KFQLS--GQKLFIPQITTKHSGLYACSVRNSATGKES 283



 Score =  126 bits (316), Expect = 8e-29
 Identities = 74/178 (41%), Positives = 101/178 (56%), Gaps = 11/178 (6%)

Query: 488 RTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQSLPVSPRL 547
           R T K + ++ E PKPSISS+   P E  +AV+ TC+PE  + +YLWW+NGQSLP+S RL
Sbjct: 12  RITWKGLLLTVETPKPSISSSKLNPREAMEAVSLTCDPETPDASYLWWMNGQSLPMSHRL 71

Query: 548 QLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISPPDSSYLS 607
           QLS  NRTL L  VT+  A  Y C I+N VSA+RSDP TL++L     P I+  +     
Sbjct: 72  QLSETNRTLFLLGVTKYTAGPYECEIRNPVSASRSDPFTLNLLPKLPKPYITINNLKPRE 131

Query: 608 GAN-LNLSCHSASNPSPQYSWRING--IPQQ-------HTQVLFIAKITPNNNGTYAC 655
             + LN +C   S  +  Y W +NG  +P           ++L +  +T N  G Y C
Sbjct: 132 NKDVLNFTCEPKSE-NYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYQC 188


>gi|52317156 carcinoembryonic antigen-related cell adhesion molecule
           isoform 2 [Homo sapiens]
          Length = 292

 Score =  221 bits (563), Expect = 2e-57
 Identities = 116/235 (49%), Positives = 146/235 (62%), Gaps = 1/235 (0%)

Query: 1   MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ 60
           M  PSA PHR CIPWQ LLLTASLLTFWN PTTA L I S PF VAEG+ V L V  LP+
Sbjct: 1   MGPPSACPHRECIPWQGLLLTASLLTFWNAPTTAWLFIASAPFEVAEGENVHLSVVYLPE 60

Query: 61  HLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFY 120
           +L+ Y WYKG+ V+ N+ I  YVI T   TPGPAYSGRE I P+  L  QN+   DTG+Y
Sbjct: 61  NLYSYGWYKGKTVEPNQLIAAYVIDTHVRTPGPAYSGRETISPSGDLHFQNVTLEDTGYY 120

Query: 121 TLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWV 180
            L V   +   E+A+   RVY  + +PSI + +S  V +K +V  TC       ++ W  
Sbjct: 121 NLQVTYRNSQIEQASHHLRVYESVAQPSIQA-SSTTVTEKGSVVLTCHTNNTGTSFQWIF 179

Query: 181 NNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLY 235
           NNQ L V+ R++LS  N  LT+  + + D   Y+CE  NPVS+ RSD + L V Y
Sbjct: 180 NNQRLQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVSNPVSSNRSDPLKLTVKY 234



 Score = 74.3 bits (181), Expect = 4e-13
 Identities = 44/131 (33%), Positives = 69/131 (52%), Gaps = 2/131 (1%)

Query: 461 ELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVA 520
           +L   N+T +++G Y  Q     S   + +   + V   + +PSI ++ S  V +K +V 
Sbjct: 106 DLHFQNVTLEDTGYYNLQVTYRNSQIEQAS-HHLRVYESVAQPSIQAS-STTVTEKGSVV 163

Query: 521 FTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSAN 580
            TC      T++ W  N Q L V+ R++LS  N  LT+  + + DA  Y C + N VS+N
Sbjct: 164 LTCHTNNTGTSFQWIFNNQRLQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVSNPVSSN 223

Query: 581 RSDPVTLDVLY 591
           RSDP+ L V Y
Sbjct: 224 RSDPLKLTVKY 234



 Score = 73.9 bits (180), Expect = 5e-13
 Identities = 41/131 (31%), Positives = 71/131 (54%), Gaps = 2/131 (1%)

Query: 283 ELFIPNITVNNSGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVA 342
           +L   N+T+ ++G Y  Q    ++ + + +   + VY    +P I ++ S  V ++ +V 
Sbjct: 106 DLHFQNVTLEDTGYYNLQVTYRNSQIEQAS-HHLRVYESVAQPSIQAS-STTVTEKGSVV 163

Query: 343 LTCEPEIQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVD 402
           LTC      T++ W  NNQ L V+ R++LS  N  LT+  + + D G Y+C + N +S +
Sbjct: 164 LTCHTNNTGTSFQWIFNNQRLQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVSNPVSSN 223

Query: 403 HSDPVILNVLY 413
            SDP+ L V Y
Sbjct: 224 RSDPLKLTVKY 234



 Score = 38.5 bits (88), Expect = 0.021
 Identities = 41/152 (26%), Positives = 59/152 (38%), Gaps = 20/152 (13%)

Query: 560 NVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISPPDSSYLSGANLNLSCHSAS 619
           NVT  D   Y   +    S        L V      P I    ++     ++ L+CH+ +
Sbjct: 111 NVTLEDTGYYNLQVTYRNSQIEQASHHLRVYESVAQPSIQASSTTVTEKGSVVLTCHT-N 169

Query: 620 NPSPQYSWRINGIPQQHTQ---------VLFIAKITPNNNGTYACFVSNLATGRNNSIVK 670
           N    + W  N    Q T+         VL I  I   + G Y C VSN  +   +  +K
Sbjct: 170 NTGTSFQWIFNNQRLQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVSNPVSSNRSDPLK 229

Query: 671 SITVSASGTSPGLSAGATVGIMIGVLVGVALI 702
            +TV    T         +GI+IGVLVG  L+
Sbjct: 230 -LTVKYDNT---------LGILIGVLVGSLLV 251



 Score = 35.4 bits (80), Expect = 0.18
 Identities = 32/124 (25%), Positives = 47/124 (37%), Gaps = 11/124 (8%)

Query: 204 NVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTISPLNTSYRSGENLNLSCHAAS 263
           NVT  DT  Y  +     S     S  L V      P+I   +T+     ++ L+CH  +
Sbjct: 111 NVTLEDTGYYNLQVTYRNSQIEQASHHLRVYESVAQPSIQASSTTVTEKGSVVLTCH-TN 169

Query: 264 NPPAQYSWFVNGTFQQSTQE---------LFIPNITVNNSGSYTCQAHNSDTGLNRTTVT 314
           N    + W  N    Q T+          L I  I   ++G Y C+  N     NR+   
Sbjct: 170 NTGTSFQWIFNNQRLQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVSN-PVSSNRSDPL 228

Query: 315 TITV 318
            +TV
Sbjct: 229 KLTV 232


>gi|148612793 carcinoembryonic antigen-related cell adhesion
           molecule isoform 1 [Homo sapiens]
          Length = 293

 Score =  219 bits (558), Expect = 7e-57
 Identities = 115/233 (49%), Positives = 145/233 (62%), Gaps = 1/233 (0%)

Query: 1   MESPSAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ 60
           M  PSA PHR CIPWQ LLLTASLLTFWN PTTA L I S PF VAEG+ V L V  LP+
Sbjct: 1   MGPPSACPHRECIPWQGLLLTASLLTFWNAPTTAWLFIASAPFEVAEGENVHLSVVYLPE 60

Query: 61  HLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFY 120
           +L+ Y WYKG+ V+ N+ I  YVI T   TPGPAYSGRE I P+  L  QN+   DTG+Y
Sbjct: 61  NLYSYGWYKGKTVEPNQLIAAYVIDTHVRTPGPAYSGRETISPSGDLHFQNVTLEDTGYY 120

Query: 121 TLHVIKSDLVNEEATGQFRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWV 180
            L V   +   E+A+   RVY  + +PSI + +S  V +K +V  TC       ++ W  
Sbjct: 121 NLQVTYRNSQIEQASHHLRVYESVAQPSIQA-SSTTVTEKGSVVLTCHTNNTGTSFQWIF 179

Query: 181 NNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNV 233
           NNQ L V+ R++LS  N  LT+  + + D   Y+CE  NPVS+ RSD + L V
Sbjct: 180 NNQRLQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVSNPVSSNRSDPLKLTV 232



 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 43/138 (31%), Positives = 74/138 (53%), Gaps = 4/138 (2%)

Query: 283 ELFIPNITVNNSGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVA 342
           +L   N+T+ ++G Y  Q    ++ + + +   + VY    +P I ++ S  V ++ +V 
Sbjct: 106 DLHFQNVTLEDTGYYNLQVTYRNSQIEQAS-HHLRVYESVAQPSIQAS-STTVTEKGSVV 163

Query: 343 LTCEPEIQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVGPYECGIQNKLSVD 402
           LTC      T++ W  NNQ L V+ R++LS  N  LT+  + + D G Y+C + N +S +
Sbjct: 164 LTCHTNNTGTSFQWIFNNQRLQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVSNPVSSN 223

Query: 403 HSDPVILNVLYGPDDPTI 420
            SDP+ L V    DD T+
Sbjct: 224 RSDPLKLTV--KSDDNTL 239



 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 43/129 (33%), Positives = 68/129 (52%), Gaps = 2/129 (1%)

Query: 461 ELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVA 520
           +L   N+T +++G Y  Q     S   + +   + V   + +PSI ++ S  V +K +V 
Sbjct: 106 DLHFQNVTLEDTGYYNLQVTYRNSQIEQAS-HHLRVYESVAQPSIQAS-STTVTEKGSVV 163

Query: 521 FTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSAN 580
            TC      T++ W  N Q L V+ R++LS  N  LT+  + + DA  Y C + N VS+N
Sbjct: 164 LTCHTNNTGTSFQWIFNNQRLQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVSNPVSSN 223

Query: 581 RSDPVTLDV 589
           RSDP+ L V
Sbjct: 224 RSDPLKLTV 232



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 41/152 (26%), Positives = 60/152 (39%), Gaps = 19/152 (12%)

Query: 560 NVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISPPDSSYLSGANLNLSCHSAS 619
           NVT  D   Y   +    S        L V      P I    ++     ++ L+CH+ +
Sbjct: 111 NVTLEDTGYYNLQVTYRNSQIEQASHHLRVYESVAQPSIQASSTTVTEKGSVVLTCHT-N 169

Query: 620 NPSPQYSWRINGIPQQHTQ---------VLFIAKITPNNNGTYACFVSNLATGRNNSIVK 670
           N    + W  N    Q T+         VL I  I   + G Y C VSN  +   +  +K
Sbjct: 170 NTGTSFQWIFNNQRLQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVSNPVSSNRSDPLK 229

Query: 671 SITVSASGTSPGLSAGATVGIMIGVLVGVALI 702
            +TV +           T+GI+IGVLVG  L+
Sbjct: 230 -LTVKSDDN--------TLGILIGVLVGSLLV 252



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 32/127 (25%), Positives = 49/127 (38%), Gaps = 11/127 (8%)

Query: 204 NVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTISPLNTSYRSGENLNLSCHAAS 263
           NVT  DT  Y  +     S     S  L V      P+I   +T+     ++ L+CH  +
Sbjct: 111 NVTLEDTGYYNLQVTYRNSQIEQASHHLRVYESVAQPSIQASSTTVTEKGSVVLTCH-TN 169

Query: 264 NPPAQYSWFVNGTFQQSTQE---------LFIPNITVNNSGSYTCQAHNSDTGLNRTTVT 314
           N    + W  N    Q T+          L I  I   ++G Y C+  N     NR+   
Sbjct: 170 NTGTSFQWIFNNQRLQVTKRMKLSWFNHVLTIDPIRQEDAGEYQCEVSN-PVSSNRSDPL 228

Query: 315 TITVYAE 321
            +TV ++
Sbjct: 229 KLTVKSD 235


>gi|164663826 pregnancy specific beta-1-glycoprotein 11 isoform 2
           [Homo sapiens]
          Length = 213

 Score =  211 bits (536), Expect = 2e-54
 Identities = 108/189 (57%), Positives = 125/189 (66%)

Query: 143 ELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTL 202
           E PKPSISS+N  P E  + V  TC PET DA+YLWW+N QSLP++ R+QLS  NRTL L
Sbjct: 23  ETPKPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFL 82

Query: 203 FNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTISPLNTSYRSGENLNLSCHAA 262
           F VT+     Y+CE  N  SA RSD V LN+L+GPD P I P  TSY SGENL+LSC A 
Sbjct: 83  FGVTKYTAGPYECEIWNSGSASRSDPVTLNLLHGPDLPRIFPSVTSYYSGENLDLSCFAN 142

Query: 263 SNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQAHNSDTGLNRTTVTTITVYAEP 322
           SNPPAQYSW +NG FQ S Q+LFIP IT  ++G Y C A NS TG   +T  TI V A P
Sbjct: 143 SNPPAQYSWTINGKFQLSGQKLFIPQITPKHNGLYACSARNSATGEESSTSLTIRVIAPP 202

Query: 323 PKPFITSNN 331
                  NN
Sbjct: 203 GLGTFAFNN 211



 Score =  199 bits (506), Expect = 7e-51
 Identities = 102/189 (53%), Positives = 122/189 (64%)

Query: 321 EPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTL 380
           E PKP I+S+N NP E  + V LTC PE  + +YLWW+N QSLP++ R+QLS  NRTL L
Sbjct: 23  ETPKPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFL 82

Query: 381 LSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTISPSYTYYRPGVNLSLSCHAA 440
             VT+   GPYEC I N  S   SDPV LN+L+GPD P I PS T Y  G NL LSC A 
Sbjct: 83  FGVTKYTAGPYECEIWNSGSASRSDPVTLNLLHGPDLPRIFPSVTSYYSGENLDLSCFAN 142

Query: 441 SNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAEL 500
           SNPPAQYSW I+G  Q   Q+LFI  IT K++GLY C A NSA+G   +T  TI V A  
Sbjct: 143 SNPPAQYSWTINGKFQLSGQKLFIPQITPKHNGLYACSARNSATGEESSTSLTIRVIAPP 202

Query: 501 PKPSISSNN 509
              + + NN
Sbjct: 203 GLGTFAFNN 211



 Score =  196 bits (499), Expect = 5e-50
 Identities = 105/196 (53%), Positives = 128/196 (65%), Gaps = 3/196 (1%)

Query: 492 KTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQSLPVSPRLQLSN 551
           K + ++ E PKPSISS+N  P E  + V  TC PE  + +YLWW+NGQSLP++ R+QLS 
Sbjct: 16  KGLLLTVETPKPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSE 75

Query: 552 GNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISPPDSSYLSGANL 611
            NRTL LF VT+  A  Y C I NS SA+RSDPVTL++L+GPD P I P  +SY SG NL
Sbjct: 76  TNRTLFLFGVTKYTAGPYECEIWNSGSASRSDPVTLNLLHGPDLPRIFPSVTSYYSGENL 135

Query: 612 NLSCHSASNPSPQYSWRINGIPQQHTQVLFIAKITPNNNGTYACFVSNLATGRNNSIVKS 671
           +LSC + SNP  QYSW ING  Q   Q LFI +ITP +NG YAC   N ATG  +S   +
Sbjct: 136 DLSCFANSNPPAQYSWTINGKFQLSGQKLFIPQITPKHNGLYACSARNSATGEESSTSLT 195

Query: 672 ITVSASGTSPGLSAGA 687
           I V A    PGL   A
Sbjct: 196 IRVIA---PPGLGTFA 208



 Score = 37.4 bits (85), Expect = 0.048
 Identities = 57/244 (23%), Positives = 89/244 (36%), Gaps = 45/244 (18%)

Query: 5   SAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQHLFG 64
           SAPP    I W+ LLLT           T K +I S+  N  E  E ++L  N       
Sbjct: 5   SAPPCTEHIKWKGLLLTVE---------TPKPSISSSNLNPREAMETVILTCNPETPDAS 55

Query: 65  YSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFYTLHV 124
           Y W+       N Q +            P     ++   N +L +  + +   G Y   +
Sbjct: 56  YLWWM------NGQSL------------PMTHRMQLSETNRTLFLFGVTKYTAGPYECEI 97

Query: 125 IKSDLV--NEEATGQFRVYPELPK--PSISSNNSKPVEDKDAVAFTCEPETQDATYLWWV 180
             S     ++  T      P+LP+  PS++S  S    D    A +  P    A Y W +
Sbjct: 98  WNSGSASRSDPVTLNLLHGPDLPRIFPSVTSYYSGENLDLSCFANSNPP----AQYSWTI 153

Query: 181 NNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSD-SVILNVLYGPDA 239
           N        + QLS   + L +  +T      Y C  +N  +   S  S+ + V+  P  
Sbjct: 154 NG-------KFQLS--GQKLFIPQITPKHNGLYACSARNSATGEESSTSLTIRVIAPPGL 204

Query: 240 PTIS 243
            T +
Sbjct: 205 GTFA 208


>gi|164663824 pregnancy specific beta-1-glycoprotein 11 isoform 2
           [Homo sapiens]
          Length = 213

 Score =  211 bits (536), Expect = 2e-54
 Identities = 108/189 (57%), Positives = 125/189 (66%)

Query: 143 ELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTL 202
           E PKPSISS+N  P E  + V  TC PET DA+YLWW+N QSLP++ R+QLS  NRTL L
Sbjct: 23  ETPKPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFL 82

Query: 203 FNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTISPLNTSYRSGENLNLSCHAA 262
           F VT+     Y+CE  N  SA RSD V LN+L+GPD P I P  TSY SGENL+LSC A 
Sbjct: 83  FGVTKYTAGPYECEIWNSGSASRSDPVTLNLLHGPDLPRIFPSVTSYYSGENLDLSCFAN 142

Query: 263 SNPPAQYSWFVNGTFQQSTQELFIPNITVNNSGSYTCQAHNSDTGLNRTTVTTITVYAEP 322
           SNPPAQYSW +NG FQ S Q+LFIP IT  ++G Y C A NS TG   +T  TI V A P
Sbjct: 143 SNPPAQYSWTINGKFQLSGQKLFIPQITPKHNGLYACSARNSATGEESSTSLTIRVIAPP 202

Query: 323 PKPFITSNN 331
                  NN
Sbjct: 203 GLGTFAFNN 211



 Score =  199 bits (506), Expect = 7e-51
 Identities = 102/189 (53%), Positives = 122/189 (64%)

Query: 321 EPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTL 380
           E PKP I+S+N NP E  + V LTC PE  + +YLWW+N QSLP++ R+QLS  NRTL L
Sbjct: 23  ETPKPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSETNRTLFL 82

Query: 381 LSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTISPSYTYYRPGVNLSLSCHAA 440
             VT+   GPYEC I N  S   SDPV LN+L+GPD P I PS T Y  G NL LSC A 
Sbjct: 83  FGVTKYTAGPYECEIWNSGSASRSDPVTLNLLHGPDLPRIFPSVTSYYSGENLDLSCFAN 142

Query: 441 SNPPAQYSWLIDGNIQQHTQELFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAEL 500
           SNPPAQYSW I+G  Q   Q+LFI  IT K++GLY C A NSA+G   +T  TI V A  
Sbjct: 143 SNPPAQYSWTINGKFQLSGQKLFIPQITPKHNGLYACSARNSATGEESSTSLTIRVIAPP 202

Query: 501 PKPSISSNN 509
              + + NN
Sbjct: 203 GLGTFAFNN 211



 Score =  196 bits (499), Expect = 5e-50
 Identities = 105/196 (53%), Positives = 128/196 (65%), Gaps = 3/196 (1%)

Query: 492 KTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQSLPVSPRLQLSN 551
           K + ++ E PKPSISS+N  P E  + V  TC PE  + +YLWW+NGQSLP++ R+QLS 
Sbjct: 16  KGLLLTVETPKPSISSSNLNPREAMETVILTCNPETPDASYLWWMNGQSLPMTHRMQLSE 75

Query: 552 GNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISPPDSSYLSGANL 611
            NRTL LF VT+  A  Y C I NS SA+RSDPVTL++L+GPD P I P  +SY SG NL
Sbjct: 76  TNRTLFLFGVTKYTAGPYECEIWNSGSASRSDPVTLNLLHGPDLPRIFPSVTSYYSGENL 135

Query: 612 NLSCHSASNPSPQYSWRINGIPQQHTQVLFIAKITPNNNGTYACFVSNLATGRNNSIVKS 671
           +LSC + SNP  QYSW ING  Q   Q LFI +ITP +NG YAC   N ATG  +S   +
Sbjct: 136 DLSCFANSNPPAQYSWTINGKFQLSGQKLFIPQITPKHNGLYACSARNSATGEESSTSLT 195

Query: 672 ITVSASGTSPGLSAGA 687
           I V A    PGL   A
Sbjct: 196 IRVIA---PPGLGTFA 208



 Score = 37.4 bits (85), Expect = 0.048
 Identities = 57/244 (23%), Positives = 89/244 (36%), Gaps = 45/244 (18%)

Query: 5   SAPPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQHLFG 64
           SAPP    I W+ LLLT           T K +I S+  N  E  E ++L  N       
Sbjct: 5   SAPPCTEHIKWKGLLLTVE---------TPKPSISSSNLNPREAMETVILTCNPETPDAS 55

Query: 65  YSWYKGERVDGNRQIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFYTLHV 124
           Y W+       N Q +            P     ++   N +L +  + +   G Y   +
Sbjct: 56  YLWWM------NGQSL------------PMTHRMQLSETNRTLFLFGVTKYTAGPYECEI 97

Query: 125 IKSDLV--NEEATGQFRVYPELPK--PSISSNNSKPVEDKDAVAFTCEPETQDATYLWWV 180
             S     ++  T      P+LP+  PS++S  S    D    A +  P    A Y W +
Sbjct: 98  WNSGSASRSDPVTLNLLHGPDLPRIFPSVTSYYSGENLDLSCFANSNPP----AQYSWTI 153

Query: 181 NNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQNPVSARRSD-SVILNVLYGPDA 239
           N        + QLS   + L +  +T      Y C  +N  +   S  S+ + V+  P  
Sbjct: 154 NG-------KFQLS--GQKLFIPQITPKHNGLYACSARNSATGEESSTSLTIRVIAPPGL 204

Query: 240 PTIS 243
            T +
Sbjct: 205 GTFA 208


>gi|156564378 carcinoembryonic antigen-related cell adhesion
           molecule 20 5L [Homo sapiens]
          Length = 596

 Score =  202 bits (515), Expect = 7e-52
 Identities = 131/398 (32%), Positives = 193/398 (48%), Gaps = 19/398 (4%)

Query: 321 EPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTL 380
           E  KP I  +    +E +D V   C  +  N T  W  NN S+    R+QLS D + LT+
Sbjct: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125

Query: 381 LSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTI-------SPSYTYYRPGVNL 433
           L V R D G Y+C  ++ L    SDP+ L+V YGPD   I       S        G ++
Sbjct: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185

Query: 434 SLSCHAASNPPAQYSWLIDGNIQQHTQELF-ISNITEKNSGLYTCQANNSASGHSRTTVK 492
           +      S+PP  Y+W +  +I  HT   F I  ++ ++ GLY C  +NSA+  S     
Sbjct: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245

Query: 493 TITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNG 552
            + V   L  P +  ++   VE+  +V  TC+   Q+    W+++GQ L  S  LQLS  
Sbjct: 246 KVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSAD 305

Query: 553 NRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISPPDSSYL------ 606
           NRTL +  + RND   Y C + N  S  RS+P+ L + YGPD   I+   +S +      
Sbjct: 306 NRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEA 365

Query: 607 -SGANLNLSCHSASNPSPQYSWRINGIPQQHT-QVLFIAKITPNNNGTYACFVSNLATGR 664
              ++L L C + S P  +Y W +     +H  + L I  +T  ++G Y C  SN  TG 
Sbjct: 366 ELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGL 425

Query: 665 NNSIVKSITVSASG-TSPGLSAGATVGIMIGVLVGVAL 701
             S   S+ V   G  S  LS+GA  GI+IG+L  +A+
Sbjct: 426 ARS--TSVLVKVVGPQSSSLSSGAIAGIVIGILAVIAV 461



 Score =  200 bits (508), Expect = 4e-51
 Identities = 122/371 (32%), Positives = 190/371 (51%), Gaps = 18/371 (4%)

Query: 143 ELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTL 202
           EL KPSI+ +    +E KD V F C  +  + T  W  NN S+    R+QLS   + LT+
Sbjct: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125

Query: 203 FNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTISPLNTSYRSGE--------N 254
             V R D+ +Y+CE ++ + ++RSD + L+V YGPD P    L +   SGE        +
Sbjct: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPD-PVEIKLESGVASGEVVEVMEGSS 184

Query: 255 LNLSCHAASNPPAQYSWFV-NGTFQQSTQELFIPNITVNNSGSYTCQAHNSDTGLNRTTV 313
           +       S+PP  Y+WF+ +     +T+   I  ++  + G Y C   NS T L+    
Sbjct: 185 MTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGT 244

Query: 314 TTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQSLPVSPRLQLSN 373
             + V      P +  ++ N VE+  +V LTC+   Q+    W+++ Q L  S  LQLS 
Sbjct: 245 LKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSA 304

Query: 374 DNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTISP-------SYTY 426
           DNRTL +  + RND GPY C + N  S   S+P+ L + YGPD   I+        S   
Sbjct: 305 DNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIE 364

Query: 427 YRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHT-QELFISNITEKNSGLYTCQANNSASG 485
                +L+L C A S P A+Y W ++ +  +H  ++L I  +T ++ G+Y C A+NS +G
Sbjct: 365 AELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTG 424

Query: 486 HSRTTVKTITV 496
            +R+T   + V
Sbjct: 425 LARSTSVLVKV 435



 Score =  108 bits (270), Expect = 2e-23
 Identities = 74/233 (31%), Positives = 111/233 (47%), Gaps = 22/233 (9%)

Query: 108 LIQNIIQNDTGFYTLHVIKSD-------LVNEEATG-------QFRVYPELPKPSISSNN 153
           L+ +I+ + T  +T+H +  +       LV+  AT        + RV   L  P +  ++
Sbjct: 203 LLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSS 262

Query: 154 SKPVEDKDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASY 213
              VE+  +V  TC+   Q     W+++ Q L  S  LQLS  NRTL +  + RNDT  Y
Sbjct: 263 LNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPY 322

Query: 214 KCETQNPVSARRSDSVILNVLYGPDAPTISPLNTS-------YRSGENLNLSCHAASNPP 266
            CE  N  S  RS+ + L + YGPD   I+  + S            +L L C A S P 
Sbjct: 323 ACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPG 382

Query: 267 AQYSWFV-NGTFQQSTQELFIPNITVNNSGSYTCQAHNSDTGLNRTTVTTITV 318
           A+Y W + + T +   ++L I  +T  + G Y C A NS TGL R+T   + V
Sbjct: 383 AEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKV 435



 Score = 98.2 bits (243), Expect = 2e-20
 Identities = 77/276 (27%), Positives = 121/276 (43%), Gaps = 29/276 (10%)

Query: 414 GPDDPTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSG 473
           GP D     S+ ++  G+ LS S     +PPA     ++ N    TQ         ++  
Sbjct: 2   GPAD-----SWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQS--------EDVV 48

Query: 474 LYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYL 533
           L       +   H R        S EL KPSI+ +    +E KD V F C  +  N T  
Sbjct: 49  LPVFGTPRTPQIHGR--------SRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIH 100

Query: 534 WWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGP 593
           W  N  S+    R+QLS   + LT+  V R D+  Y C  ++++ + RSDP+ LDV YGP
Sbjct: 101 WVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGP 160

Query: 594 D-------TPIISPPDSSYLSGANLNLSCHSASNPSPQYSW-RINGIPQQHTQVLFIAKI 645
           D       + + S      + G+++     + S+P   Y+W  ++ I    T+   I  +
Sbjct: 161 DPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAV 220

Query: 646 TPNNNGTYACFVSNLATGRNNSIVKSITVSASGTSP 681
           +  + G Y C VSN AT  ++     + V  + T P
Sbjct: 221 SREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMP 256



 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 92/460 (20%), Positives = 174/460 (37%), Gaps = 63/460 (13%)

Query: 7   PPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ--HLFG 64
           P   W   W  +LL+ASL T W+PP  A+LT+ + P +  + ++V+L V   P+   + G
Sbjct: 3   PADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHG 62

Query: 65  YS---------WYKGERVDGNRQIIGY--------VIGTQQATPGPAYSGREIIYPNASL 107
            S            G  ++    +  Y         I          +  R  +  +  +
Sbjct: 63  RSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKI 122

Query: 108 LIQNIIQ-NDTGFYTLHVIKSDLVNEEATGQFRVYPELPKP-------SISSNNSKPVED 159
           L   I+Q  D+G Y     +  L+++ +   F      P P        ++S     V +
Sbjct: 123 LTILIVQREDSGTYQCEA-RDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVME 181

Query: 160 KDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQN 219
             ++ F  E ++       W    S+       LS+  RT T+  V+R     Y+C   N
Sbjct: 182 GSSMTFLAETKSHPPCAYTWFLLDSI-------LSHTTRTFTIHAVSREHEGLYRCLVSN 234

Query: 220 PVSARRS-DSVILNVLYGPDAPTISPLNTS-YRSGENLNLSCHAASNPPAQYSWFVNG-- 275
             +   S  ++ + VL     P + P + +   +  +++L+C    N      WF++G  
Sbjct: 235 SATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTV-NQSVNVQWFLSGQP 293

Query: 276 -------TFQQSTQELFIPNITVNNSGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFIT 328
                        + L I  +  N++G Y C+  N  +   R+    +T+   P +  IT
Sbjct: 294 LLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRA-RSEPLELTINYGPDQVHIT 352

Query: 329 SNNSNPV------EDEDAVALTCEPEIQ-NTTYLWWVNNQSLPVSPRLQLSNDNRTLTLL 381
             +++ +      E   ++ L C  E +    Y W + + +          +    L + 
Sbjct: 353 RESASEMISTIEAELNSSLTLQCWAESKPGAEYRWTLEHST--------GEHLGEQLIIR 404

Query: 382 SVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTIS 421
           ++T    G Y C   N L+       +L  + GP   ++S
Sbjct: 405 ALTWEHDGIYNCTASNSLTGLARSTSVLVKVVGPQSSSLS 444



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 90/438 (20%), Positives = 158/438 (36%), Gaps = 74/438 (16%)

Query: 219 NPVSARRSDSVILNVLYGPDAP--------------TISP--------LNTSYRSGENLN 256
           NP+ A +S+ V+L V   P  P               +SP        + T Y + +++N
Sbjct: 37  NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96

Query: 257 LSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITV--NNSGSYTCQAHNSDTGLNRTTVT 314
           ++ H  SN     S   +   Q S     +  + V   +SG+Y C+A ++        + 
Sbjct: 97  ITIHWVSN---NLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIF 153

Query: 315 TITVYAEPPKPFITSN---NSNPVEDEDAVALTCEPEIQN---TTYLWWVNNQSLPVSPR 368
               Y   P      +   +   VE  +  ++T   E ++     Y W++ +        
Sbjct: 154 LDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSI------ 207

Query: 369 LQLSNDNRTLTLLSVTRNDVGPYECGIQNKLS-VDHSDPVILNVLYGPDDPTISP-SYTY 426
             LS+  RT T+ +V+R   G Y C + N  + +     + + VL     P + P S   
Sbjct: 208 --LSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNL 265

Query: 427 YRPGVNLSLSCHAASNPPAQYSWLIDG---------NIQQHTQELFISNITEKNSGLYTC 477
                ++ L+C    N      W + G          +    + L I  +   ++G Y C
Sbjct: 266 VENARSVDLTCQTV-NQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYAC 324

Query: 478 QANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQN--TTYLWW 535
           +  N  S  +R+    +T++    +  I+       E    +  T E E  +  T   W 
Sbjct: 325 EVWNWGS-RARSEPLELTINYGPDQVHITR------ESASEMISTIEAELNSSLTLQCWA 377

Query: 536 VNGQSLPVSPRLQLSNG---NRTLTLFNVTRNDARAYVCGIQNSVSA-NRSDPVTLDVLY 591
            +         L+ S G      L +  +T      Y C   NS++   RS  V + V  
Sbjct: 378 ESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKV-- 435

Query: 592 GPDTPIISPPDSSYLSGA 609
                 + P  SS  SGA
Sbjct: 436 ------VGPQSSSLSSGA 447


>gi|156564393 carcinoembryonic antigen-related cell adhesion
           molecule 20 5S [Homo sapiens]
          Length = 584

 Score =  202 bits (515), Expect = 7e-52
 Identities = 131/398 (32%), Positives = 193/398 (48%), Gaps = 19/398 (4%)

Query: 321 EPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTL 380
           E  KP I  +    +E +D V   C  +  N T  W  NN S+    R+QLS D + LT+
Sbjct: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125

Query: 381 LSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTI-------SPSYTYYRPGVNL 433
           L V R D G Y+C  ++ L    SDP+ L+V YGPD   I       S        G ++
Sbjct: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185

Query: 434 SLSCHAASNPPAQYSWLIDGNIQQHTQELF-ISNITEKNSGLYTCQANNSASGHSRTTVK 492
           +      S+PP  Y+W +  +I  HT   F I  ++ ++ GLY C  +NSA+  S     
Sbjct: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245

Query: 493 TITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNG 552
            + V   L  P +  ++   VE+  +V  TC+   Q+    W+++GQ L  S  LQLS  
Sbjct: 246 KVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSAD 305

Query: 553 NRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISPPDSSYL------ 606
           NRTL +  + RND   Y C + N  S  RS+P+ L + YGPD   I+   +S +      
Sbjct: 306 NRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEA 365

Query: 607 -SGANLNLSCHSASNPSPQYSWRINGIPQQHT-QVLFIAKITPNNNGTYACFVSNLATGR 664
              ++L L C + S P  +Y W +     +H  + L I  +T  ++G Y C  SN  TG 
Sbjct: 366 ELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGL 425

Query: 665 NNSIVKSITVSASG-TSPGLSAGATVGIMIGVLVGVAL 701
             S   S+ V   G  S  LS+GA  GI+IG+L  +A+
Sbjct: 426 ARS--TSVLVKVVGPQSSSLSSGAIAGIVIGILAVIAV 461



 Score =  200 bits (508), Expect = 4e-51
 Identities = 122/371 (32%), Positives = 190/371 (51%), Gaps = 18/371 (4%)

Query: 143 ELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTL 202
           EL KPSI+ +    +E KD V F C  +  + T  W  NN S+    R+QLS   + LT+
Sbjct: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125

Query: 203 FNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTISPLNTSYRSGE--------N 254
             V R D+ +Y+CE ++ + ++RSD + L+V YGPD P    L +   SGE        +
Sbjct: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPD-PVEIKLESGVASGEVVEVMEGSS 184

Query: 255 LNLSCHAASNPPAQYSWFV-NGTFQQSTQELFIPNITVNNSGSYTCQAHNSDTGLNRTTV 313
           +       S+PP  Y+WF+ +     +T+   I  ++  + G Y C   NS T L+    
Sbjct: 185 MTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGT 244

Query: 314 TTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQSLPVSPRLQLSN 373
             + V      P +  ++ N VE+  +V LTC+   Q+    W+++ Q L  S  LQLS 
Sbjct: 245 LKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSA 304

Query: 374 DNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTISP-------SYTY 426
           DNRTL +  + RND GPY C + N  S   S+P+ L + YGPD   I+        S   
Sbjct: 305 DNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIE 364

Query: 427 YRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHT-QELFISNITEKNSGLYTCQANNSASG 485
                +L+L C A S P A+Y W ++ +  +H  ++L I  +T ++ G+Y C A+NS +G
Sbjct: 365 AELNSSLTLQCWAESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTG 424

Query: 486 HSRTTVKTITV 496
            +R+T   + V
Sbjct: 425 LARSTSVLVKV 435



 Score =  108 bits (270), Expect = 2e-23
 Identities = 74/233 (31%), Positives = 111/233 (47%), Gaps = 22/233 (9%)

Query: 108 LIQNIIQNDTGFYTLHVIKSD-------LVNEEATG-------QFRVYPELPKPSISSNN 153
           L+ +I+ + T  +T+H +  +       LV+  AT        + RV   L  P +  ++
Sbjct: 203 LLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSS 262

Query: 154 SKPVEDKDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASY 213
              VE+  +V  TC+   Q     W+++ Q L  S  LQLS  NRTL +  + RNDT  Y
Sbjct: 263 LNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPY 322

Query: 214 KCETQNPVSARRSDSVILNVLYGPDAPTISPLNTS-------YRSGENLNLSCHAASNPP 266
            CE  N  S  RS+ + L + YGPD   I+  + S            +L L C A S P 
Sbjct: 323 ACEVWNWGSRARSEPLELTINYGPDQVHITRESASEMISTIEAELNSSLTLQCWAESKPG 382

Query: 267 AQYSWFV-NGTFQQSTQELFIPNITVNNSGSYTCQAHNSDTGLNRTTVTTITV 318
           A+Y W + + T +   ++L I  +T  + G Y C A NS TGL R+T   + V
Sbjct: 383 AEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKV 435



 Score = 98.2 bits (243), Expect = 2e-20
 Identities = 77/276 (27%), Positives = 121/276 (43%), Gaps = 29/276 (10%)

Query: 414 GPDDPTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSG 473
           GP D     S+ ++  G+ LS S     +PPA     ++ N    TQ         ++  
Sbjct: 2   GPAD-----SWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQS--------EDVV 48

Query: 474 LYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYL 533
           L       +   H R        S EL KPSI+ +    +E KD V F C  +  N T  
Sbjct: 49  LPVFGTPRTPQIHGR--------SRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIH 100

Query: 534 WWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGP 593
           W  N  S+    R+QLS   + LT+  V R D+  Y C  ++++ + RSDP+ LDV YGP
Sbjct: 101 WVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGP 160

Query: 594 D-------TPIISPPDSSYLSGANLNLSCHSASNPSPQYSW-RINGIPQQHTQVLFIAKI 645
           D       + + S      + G+++     + S+P   Y+W  ++ I    T+   I  +
Sbjct: 161 DPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAV 220

Query: 646 TPNNNGTYACFVSNLATGRNNSIVKSITVSASGTSP 681
           +  + G Y C VSN AT  ++     + V  + T P
Sbjct: 221 SREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMP 256



 Score = 67.0 bits (162), Expect = 6e-11
 Identities = 92/460 (20%), Positives = 174/460 (37%), Gaps = 63/460 (13%)

Query: 7   PPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ--HLFG 64
           P   W   W  +LL+ASL T W+PP  A+LT+ + P +  + ++V+L V   P+   + G
Sbjct: 3   PADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHG 62

Query: 65  YS---------WYKGERVDGNRQIIGY--------VIGTQQATPGPAYSGREIIYPNASL 107
            S            G  ++    +  Y         I          +  R  +  +  +
Sbjct: 63  RSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKI 122

Query: 108 LIQNIIQ-NDTGFYTLHVIKSDLVNEEATGQFRVYPELPKP-------SISSNNSKPVED 159
           L   I+Q  D+G Y     +  L+++ +   F      P P        ++S     V +
Sbjct: 123 LTILIVQREDSGTYQCEA-RDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVME 181

Query: 160 KDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQN 219
             ++ F  E ++       W    S+       LS+  RT T+  V+R     Y+C   N
Sbjct: 182 GSSMTFLAETKSHPPCAYTWFLLDSI-------LSHTTRTFTIHAVSREHEGLYRCLVSN 234

Query: 220 PVSARRS-DSVILNVLYGPDAPTISPLNTS-YRSGENLNLSCHAASNPPAQYSWFVNG-- 275
             +   S  ++ + VL     P + P + +   +  +++L+C    N      WF++G  
Sbjct: 235 SATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTV-NQSVNVQWFLSGQP 293

Query: 276 -------TFQQSTQELFIPNITVNNSGSYTCQAHNSDTGLNRTTVTTITVYAEPPKPFIT 328
                        + L I  +  N++G Y C+  N  +   R+    +T+   P +  IT
Sbjct: 294 LLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWNWGSRA-RSEPLELTINYGPDQVHIT 352

Query: 329 SNNSNPV------EDEDAVALTCEPEIQ-NTTYLWWVNNQSLPVSPRLQLSNDNRTLTLL 381
             +++ +      E   ++ L C  E +    Y W + + +          +    L + 
Sbjct: 353 RESASEMISTIEAELNSSLTLQCWAESKPGAEYRWTLEHST--------GEHLGEQLIIR 404

Query: 382 SVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTIS 421
           ++T    G Y C   N L+       +L  + GP   ++S
Sbjct: 405 ALTWEHDGIYNCTASNSLTGLARSTSVLVKVVGPQSSSLS 444



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 90/438 (20%), Positives = 158/438 (36%), Gaps = 74/438 (16%)

Query: 219 NPVSARRSDSVILNVLYGPDAP--------------TISP--------LNTSYRSGENLN 256
           NP+ A +S+ V+L V   P  P               +SP        + T Y + +++N
Sbjct: 37  NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96

Query: 257 LSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITV--NNSGSYTCQAHNSDTGLNRTTVT 314
           ++ H  SN     S   +   Q S     +  + V   +SG+Y C+A ++        + 
Sbjct: 97  ITIHWVSN---NLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIF 153

Query: 315 TITVYAEPPKPFITSN---NSNPVEDEDAVALTCEPEIQN---TTYLWWVNNQSLPVSPR 368
               Y   P      +   +   VE  +  ++T   E ++     Y W++ +        
Sbjct: 154 LDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSI------ 207

Query: 369 LQLSNDNRTLTLLSVTRNDVGPYECGIQNKLS-VDHSDPVILNVLYGPDDPTISP-SYTY 426
             LS+  RT T+ +V+R   G Y C + N  + +     + + VL     P + P S   
Sbjct: 208 --LSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNL 265

Query: 427 YRPGVNLSLSCHAASNPPAQYSWLIDG---------NIQQHTQELFISNITEKNSGLYTC 477
                ++ L+C    N      W + G          +    + L I  +   ++G Y C
Sbjct: 266 VENARSVDLTCQTV-NQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYAC 324

Query: 478 QANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQN--TTYLWW 535
           +  N  S  +R+    +T++    +  I+       E    +  T E E  +  T   W 
Sbjct: 325 EVWNWGS-RARSEPLELTINYGPDQVHITR------ESASEMISTIEAELNSSLTLQCWA 377

Query: 536 VNGQSLPVSPRLQLSNG---NRTLTLFNVTRNDARAYVCGIQNSVSA-NRSDPVTLDVLY 591
            +         L+ S G      L +  +T      Y C   NS++   RS  V + V  
Sbjct: 378 ESKPGAEYRWTLEHSTGEHLGEQLIIRALTWEHDGIYNCTASNSLTGLARSTSVLVKV-- 435

Query: 592 GPDTPIISPPDSSYLSGA 609
                 + P  SS  SGA
Sbjct: 436 ------VGPQSSSLSSGA 447


>gi|85861202 carcinoembryonic antigen-related cell adhesion molecule
           16 [Homo sapiens]
          Length = 484

 Score =  177 bits (448), Expect = 4e-44
 Identities = 116/357 (32%), Positives = 177/357 (49%), Gaps = 17/357 (4%)

Query: 18  LLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQHLFGYSWYKGERVDGNR 77
           LLL+A   TF N      +T+E  P   +EG  V L+VH L   L  YSWY G  +  + 
Sbjct: 68  LLLSA---TFLNVGAEISITLE--PAQPSEGDNVTLVVHGLSGELLAYSWYAGPTLSVSY 122

Query: 78  QIIGYVIGTQQATPGPAYSGREIIYPNASLLIQNIIQNDTGFYTLHVIKSDLVNEEATGQ 137
            +  Y++ T   TPGPA++GRE + P+ SL IQ I+   +G Y L      L  E   G 
Sbjct: 123 LVASYIVSTGDETPGPAHTGREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTEVGYGH 182

Query: 138 FRVYPELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGN 197
            +V+  L +P++ +N++  VE +D +   C   +  A   W+ N  +LPV+ RL LS   
Sbjct: 183 VQVHEILAQPTVLANSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDG 242

Query: 198 RTLTLFNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTISPLNTSYRSG----- 252
           R L    + R +  +Y+CE  NPVS  RS+ + L V +GP+   I   +T+ R+G     
Sbjct: 243 RVLARHGIRREEAGAYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDSTT-RTGCTIKV 301

Query: 253 ---ENLNLSCHAASNPPAQYSWFVNGTFQQSTQE-LFIPNITVNNSGSYTCQAHNSDTGL 308
               +L L C + S P  +Y W  NG   ++ Q+ L I ++T    G+YTC A N+ T L
Sbjct: 302 DFNTSLTLWCVSRSCPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLL 361

Query: 309 NRTTVTTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQN-TTYLWWVNNQSLP 364
           + +    + + A      I    + P E +D V LT +   ++   Y W+    S P
Sbjct: 362 SGSASVVVKLSAAAVATMIVPVPTKPTEGQD-VTLTVQGYPKDLLVYAWYRGPASEP 417



 Score =  109 bits (272), Expect = 1e-23
 Identities = 94/352 (26%), Positives = 139/352 (39%), Gaps = 48/352 (13%)

Query: 241 TISPLNTSYRSGENLNLSCHAASNPPAQYSWFVNGTFQQS-------------------- 280
           T+ P   S   G+N+ L  H  S     YSW+   T   S                    
Sbjct: 84  TLEPAQPS--EGDNVTLVVHGLSGELLAYSWYAGPTLSVSYLVASYIVSTGDETPGPAHT 141

Query: 281 -------TQELFIPNITVNNSGSYTCQAHN----SDTGLNRTTVTTITVYAEPPKPFITS 329
                     L I  I   +SG+Y  Q  N    ++ G     V  I       +P + +
Sbjct: 142 GREAVRPDGSLDIQGILPRHSGTYILQTFNRQLQTEVGYGHVQVHEILA-----QPTVLA 196

Query: 330 NNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTLLSVTRNDVG 389
           N++  VE  D + L C          W+ N  +LPV+ RL LS D R L    + R + G
Sbjct: 197 NSTALVERRDTLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARHGIRREEAG 256

Query: 390 PYECGIQNKLSVDHSDPVILNVLYGPDDPTISPSYTYYRPG--------VNLSLSCHAAS 441
            Y+C + N +SV  S+P+ L V +GP+   I    T  R G         +L+L C + S
Sbjct: 257 AYQCEVWNPVSVSRSEPINLTVYFGPERVAILQDST-TRTGCTIKVDFNTSLTLWCVSRS 315

Query: 442 NPPAQYSWLIDGNIQQHTQE-LFISNITEKNSGLYTCQANNSASGHSRTTVKTITVSAEL 500
            P  +Y W  +G   ++ Q+ L IS++T    G YTC A N+ +  S +    + +SA  
Sbjct: 316 CPEPEYVWTFNGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLLSGSASVVVKLSAAA 375

Query: 501 PKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNG 552
               I    +KP E +D              Y W+    S P     QL +G
Sbjct: 376 VATMIVPVPTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQLPSG 427



 Score =  104 bits (260), Expect = 2e-22
 Identities = 73/232 (31%), Positives = 110/232 (47%), Gaps = 19/232 (8%)

Query: 462 LFISNITEKNSGLYTCQANN----SASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKD 517
           L I  I  ++SG Y  Q  N    +  G+    V  I     L +P++ +N++  VE +D
Sbjct: 152 LDIQGILPRHSGTYILQTFNRQLQTEVGYGHVQVHEI-----LAQPTVLANSTALVERRD 206

Query: 518 AVAFTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSV 577
            +   C   +      W+ NG +LPV+ RL LS   R L    + R +A AY C + N V
Sbjct: 207 TLRLMCSSPSPTAEVRWFFNGGALPVALRLGLSPDGRVLARHGIRREEAGAYQCEVWNPV 266

Query: 578 SANRSDPVTLDVLYGPDTPIISPPDSSYLSG--------ANLNLSCHSASNPSPQYSWRI 629
           S +RS+P+ L V +GP+   I   DS+  +G         +L L C S S P P+Y W  
Sbjct: 267 SVSRSEPINLTVYFGPERVAIL-QDSTTRTGCTIKVDFNTSLTLWCVSRSCPEPEYVWTF 325

Query: 630 NGIPQQHTQ-VLFIAKITPNNNGTYACFVSNLATGRNNSIVKSITVSASGTS 680
           NG   ++ Q  L I+ +T    GTY C   N  T  + S    + +SA+  +
Sbjct: 326 NGQALKNGQDHLNISSMTAAQEGTYTCIAKNTKTLLSGSASVVVKLSAAAVA 377



 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 39/105 (37%), Positives = 55/105 (52%), Gaps = 2/105 (1%)

Query: 38  IESTPFNVAEGKEVLLLVHNLPQHLFGYSWYKGERVDGNRQIIGYVIGTQQATPGPAYSG 97
           I   P    EG++V L V   P+ L  Y+WY+G   + NR +     GT  A  GPA++G
Sbjct: 380 IVPVPTKPTEGQDVTLTVQGYPKDLLVYAWYRGPASEPNRLLSQLPSGTWIA--GPAHTG 437

Query: 98  REIIYPNASLLIQNIIQNDTGFYTLHVIKSDLVNEEATGQFRVYP 142
           RE+ +PN SLL+Q +   DTG YTL  +      E    + +V P
Sbjct: 438 REVGFPNCSLLVQKLNLTDTGRYTLKTVTVQGKTETLEVELQVAP 482


>gi|156564390 carcinoembryonic antigen-related cell adhesion
           molecule 20 4L [Homo sapiens]
          Length = 503

 Score =  156 bits (395), Expect = 5e-38
 Identities = 93/278 (33%), Positives = 142/278 (51%), Gaps = 10/278 (3%)

Query: 143 ELPKPSISSNNSKPVEDKDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTL 202
           EL KPSI+ +    +E KD V F C  +  + T  W  NN S+    R+QLS   + LT+
Sbjct: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125

Query: 203 FNVTRNDTASYKCETQNPVSARRSDSVILNVLYGPDAPTISPLNTSYRSGE--------N 254
             V R D+ +Y+CE ++ + ++RSD + L+V YGPD P    L +   SGE        +
Sbjct: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPD-PVEIKLESGVASGEVVEVMEGSS 184

Query: 255 LNLSCHAASNPPAQYSWF-VNGTFQQSTQELFIPNITVNNSGSYTCQAHNSDTGLNRTTV 313
           +       S+PP  Y+WF ++     +T+   I  ++  + G Y C   NS T L+    
Sbjct: 185 MTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGT 244

Query: 314 TTITVYAEPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQSLPVSPRLQLSN 373
             + V      P +  ++ N VE+  +V LTC+   Q+    W+++ Q L  S  LQLS 
Sbjct: 245 LKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSA 304

Query: 374 DNRTLTLLSVTRNDVGPYECGIQNKLSVDHSDPVILNV 411
           DNRTL +  + RND GPY C + N  S   S+P+ L +
Sbjct: 305 DNRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLELTI 342



 Score =  154 bits (390), Expect = 2e-37
 Identities = 99/297 (33%), Positives = 141/297 (47%), Gaps = 16/297 (5%)

Query: 321 EPPKPFITSNNSNPVEDEDAVALTCEPEIQNTTYLWWVNNQSLPVSPRLQLSNDNRTLTL 380
           E  KP I  +    +E +D V   C  +  N T  W  NN S+    R+QLS D + LT+
Sbjct: 66  ELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKILTI 125

Query: 381 LSVTRNDVGPYECGIQNKLSVDHSDPVILNVLYGPDDPTI-------SPSYTYYRPGVNL 433
           L V R D G Y+C  ++ L    SDP+ L+V YGPD   I       S        G ++
Sbjct: 126 LIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVMEGSSM 185

Query: 434 SLSCHAASNPPAQYSWLIDGNIQQHTQELF-ISNITEKNSGLYTCQANNSASGHSRTTVK 492
           +      S+PP  Y+W +  +I  HT   F I  ++ ++ GLY C  +NSA+  S     
Sbjct: 186 TFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTL 245

Query: 493 TITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQSLPVSPRLQLSNG 552
            + V   L  P +  ++   VE+  +V  TC+   Q+    W+++GQ L  S  LQLS  
Sbjct: 246 KVRVLETLTMPQVVPSSLNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSAD 305

Query: 553 NRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGPDTPIISPPDSSYLSGA 609
           NRTL +  + RND   Y C + N  S  RS+P+ L         I  P  SS  SGA
Sbjct: 306 NRTLIIHGLQRNDTGPYACEVWNWGSRARSEPLEL--------TINCPQSSSLSSGA 354



 Score = 98.2 bits (243), Expect = 2e-20
 Identities = 77/276 (27%), Positives = 121/276 (43%), Gaps = 29/276 (10%)

Query: 414 GPDDPTISPSYTYYRPGVNLSLSCHAASNPPAQYSWLIDGNIQQHTQELFISNITEKNSG 473
           GP D     S+ ++  G+ LS S     +PPA     ++ N    TQ         ++  
Sbjct: 2   GPAD-----SWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQS--------EDVV 48

Query: 474 LYTCQANNSASGHSRTTVKTITVSAELPKPSISSNNSKPVEDKDAVAFTCEPEAQNTTYL 533
           L       +   H R        S EL KPSI+ +    +E KD V F C  +  N T  
Sbjct: 49  LPVFGTPRTPQIHGR--------SRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIH 100

Query: 534 WWVNGQSLPVSPRLQLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRSDPVTLDVLYGP 593
           W  N  S+    R+QLS   + LT+  V R D+  Y C  ++++ + RSDP+ LDV YGP
Sbjct: 101 WVSNNLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIFLDVKYGP 160

Query: 594 D-------TPIISPPDSSYLSGANLNLSCHSASNPSPQYSW-RINGIPQQHTQVLFIAKI 645
           D       + + S      + G+++     + S+P   Y+W  ++ I    T+   I  +
Sbjct: 161 DPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSILSHTTRTFTIHAV 220

Query: 646 TPNNNGTYACFVSNLATGRNNSIVKSITVSASGTSP 681
           +  + G Y C VSN AT  ++     + V  + T P
Sbjct: 221 SREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMP 256



 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 47/159 (29%), Positives = 75/159 (47%), Gaps = 18/159 (11%)

Query: 108 LIQNIIQNDTGFYTLHVIKSD-------LVNEEATG-------QFRVYPELPKPSISSNN 153
           L+ +I+ + T  +T+H +  +       LV+  AT        + RV   L  P +  ++
Sbjct: 203 LLDSILSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSS 262

Query: 154 SKPVEDKDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASY 213
              VE+  +V  TC+   Q     W+++ Q L  S  LQLS  NRTL +  + RNDT  Y
Sbjct: 263 LNLVENARSVDLTCQTVNQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPY 322

Query: 214 KCETQNPVSARRSDSVILNVLYGPDAPTISPLNTSYRSG 252
            CE  N  S  RS+ + L +    + P  S L++   +G
Sbjct: 323 ACEVWNWGSRARSEPLELTI----NCPQSSSLSSGAIAG 357



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 70/335 (20%), Positives = 128/335 (38%), Gaps = 47/335 (14%)

Query: 7   PPHRWCIPWQRLLLTASLLTFWNPPTTAKLTIESTPFNVAEGKEVLLLVHNLPQ--HLFG 64
           P   W   W  +LL+ASL T W+PP  A+LT+ + P +  + ++V+L V   P+   + G
Sbjct: 3   PADSWGHHWMGILLSASLCTVWSPPAAAQLTLNANPLDATQSEDVVLPVFGTPRTPQIHG 62

Query: 65  YS---------WYKGERVDGNRQIIGY--------VIGTQQATPGPAYSGREIIYPNASL 107
            S            G  ++    +  Y         I          +  R  +  +  +
Sbjct: 63  RSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVNITIHWVSNNLSVVFHERMQLSKDGKI 122

Query: 108 LIQNIIQ-NDTGFYTLHVIKSDLVNEEATGQFRVYPELPKP-------SISSNNSKPVED 159
           L   I+Q  D+G Y     +  L+++ +   F      P P        ++S     V +
Sbjct: 123 LTILIVQREDSGTYQCEA-RDALLSQRSDPIFLDVKYGPDPVEIKLESGVASGEVVEVME 181

Query: 160 KDAVAFTCEPETQDATYLWWVNNQSLPVSPRLQLSNGNRTLTLFNVTRNDTASYKCETQN 219
             ++ F  E ++       W    S+       LS+  RT T+  V+R     Y+C   N
Sbjct: 182 GSSMTFLAETKSHPPCAYTWFLLDSI-------LSHTTRTFTIHAVSREHEGLYRCLVSN 234

Query: 220 PVSARRS-DSVILNVLYGPDAPTISPLNTS-YRSGENLNLSCHAASNPPAQYSWFVNG-- 275
             +   S  ++ + VL     P + P + +   +  +++L+C    N      WF++G  
Sbjct: 235 SATHLSSLGTLKVRVLETLTMPQVVPSSLNLVENARSVDLTCQTV-NQSVNVQWFLSGQP 293

Query: 276 -------TFQQSTQELFIPNITVNNSGSYTCQAHN 303
                        + L I  +  N++G Y C+  N
Sbjct: 294 LLPSEHLQLSADNRTLIIHGLQRNDTGPYACEVWN 328



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 81/345 (23%), Positives = 141/345 (40%), Gaps = 53/345 (15%)

Query: 397 NKLSVDHSDPVILNVLYGPDDPTI--------------SPS--------YTYYRPGVNLS 434
           N L    S+ V+L V   P  P I              SP          T+Y    +++
Sbjct: 37  NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96

Query: 435 LSCHAASNPPAQYSWLIDGNIQ--QHTQELFISNITEKNSGLYTCQANNSASGHSRTTVK 492
           ++ H  SN     S +    +Q  +  + L I  +  ++SG Y C+A ++        + 
Sbjct: 97  ITIHWVSN---NLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIF 153

Query: 493 TITVSAELP-----KPSISSNNSKPVEDKDAVAFTCEPEAQNTTYLWWVNGQSLPVSPRL 547
                   P     +  ++S     V +  ++ F  E ++       W    S+      
Sbjct: 154 LDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSI------ 207

Query: 548 QLSNGNRTLTLFNVTRNDARAYVCGIQNSVSANRS-DPVTLDVLYGPDTPIISPPDSSYL 606
            LS+  RT T+  V+R     Y C + NS +   S   + + VL     P + P   + +
Sbjct: 208 -LSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNLV 266

Query: 607 SGA-NLNLSCHSASNPSPQYSWRING---IPQQHTQV------LFIAKITPNNNGTYACF 656
             A +++L+C +  N S    W ++G   +P +H Q+      L I  +  N+ G YAC 
Sbjct: 267 ENARSVDLTCQTV-NQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYACE 325

Query: 657 VSNLATGRNNSIVKSITVSASGTSPGLSAGATVGIMIGVLVGVAL 701
           V N  + R  S    +T++   +S  LS+GA  GI+IG+L  +A+
Sbjct: 326 VWNWGS-RARSEPLELTINCPQSS-SLSSGAIAGIVIGILAVIAV 368



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 66/333 (19%), Positives = 124/333 (37%), Gaps = 56/333 (16%)

Query: 219 NPVSARRSDSVILNVLYGPDAP--------------TISP--------LNTSYRSGENLN 256
           NP+ A +S+ V+L V   P  P               +SP        + T Y + +++N
Sbjct: 37  NPLDATQSEDVVLPVFGTPRTPQIHGRSRELAKPSIAVSPGTAIEQKDMVTFYCTTKDVN 96

Query: 257 LSCHAASNPPAQYSWFVNGTFQQSTQELFIPNITV--NNSGSYTCQAHNSDTGLNRTTVT 314
           ++ H  SN     S   +   Q S     +  + V   +SG+Y C+A ++        + 
Sbjct: 97  ITIHWVSN---NLSVVFHERMQLSKDGKILTILIVQREDSGTYQCEARDALLSQRSDPIF 153

Query: 315 TITVYAEPPKPFITSN---NSNPVEDEDAVALTCEPEIQN---TTYLWWVNNQSLPVSPR 368
               Y   P      +   +   VE  +  ++T   E ++     Y W++ +        
Sbjct: 154 LDVKYGPDPVEIKLESGVASGEVVEVMEGSSMTFLAETKSHPPCAYTWFLLDSI------ 207

Query: 369 LQLSNDNRTLTLLSVTRNDVGPYECGIQNKLS-VDHSDPVILNVLYGPDDPTISP-SYTY 426
             LS+  RT T+ +V+R   G Y C + N  + +     + + VL     P + P S   
Sbjct: 208 --LSHTTRTFTIHAVSREHEGLYRCLVSNSATHLSSLGTLKVRVLETLTMPQVVPSSLNL 265

Query: 427 YRPGVNLSLSCHAASNPPAQYSWLIDG---------NIQQHTQELFISNITEKNSGLYTC 477
                ++ L+C    N      W + G          +    + L I  +   ++G Y C
Sbjct: 266 VENARSVDLTCQTV-NQSVNVQWFLSGQPLLPSEHLQLSADNRTLIIHGLQRNDTGPYAC 324

Query: 478 QANNSASGHSRTTVKTITVSAELPKPSISSNNS 510
           +  N     SR   + + ++   P+ S  S+ +
Sbjct: 325 EVWNWG---SRARSEPLELTINCPQSSSLSSGA 354


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.129    0.392 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,986,867
Number of Sequences: 37866
Number of extensions: 1437649
Number of successful extensions: 8403
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 172
Number of HSP's successfully gapped in prelim test: 289
Number of HSP's that attempted gapping in prelim test: 3270
Number of HSP's gapped (non-prelim): 2625
length of query: 702
length of database: 18,247,518
effective HSP length: 109
effective length of query: 593
effective length of database: 14,120,124
effective search space: 8373233532
effective search space used: 8373233532
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.