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Search of human proteins with 91718902
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
(4911 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo s... 1.006e+04 0.0
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 1088 0.0
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 188 1e-46
gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [... 181 2e-44
gi|210032580 SET domain containing 1B [Homo sapiens] 137 3e-31
gi|55741677 SET domain containing 1A [Homo sapiens] 129 7e-29
gi|205830434 D4, zinc and double PHD fingers family 1 isoform c ... 96 9e-19
gi|205830430 D4, zinc and double PHD fingers family 1 isoform a ... 96 9e-19
gi|19923202 enhancer of zeste homolog 1 [Homo sapiens] 94 3e-18
gi|23510384 enhancer of zeste 2 isoform b [Homo sapiens] 93 7e-18
gi|21361095 enhancer of zeste 2 isoform a [Homo sapiens] 93 7e-18
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 91 2e-17
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 91 2e-17
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 91 2e-17
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 91 2e-17
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 91 3e-17
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 91 3e-17
gi|205830432 D4, zinc and double PHD fingers family 1 isoform b ... 91 4e-17
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 90 6e-17
gi|197313748 SET domain containing 2 [Homo sapiens] 89 8e-17
gi|222352122 hypothetical protein LOC284297 [Homo sapiens] 89 1e-16
gi|5454004 D4, zinc and double PHD fingers family 2 [Homo sapiens] 88 2e-16
gi|116284392 mucin 2 precursor [Homo sapiens] 87 3e-16
gi|55750053 atrophin-1 [Homo sapiens] 86 1e-15
gi|55750041 atrophin-1 [Homo sapiens] 86 1e-15
gi|163965366 nascent polypeptide-associated complex alpha subuni... 85 2e-15
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 84 3e-15
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 84 5e-15
gi|119943102 CREB binding protein isoform b [Homo sapiens] 82 1e-14
gi|119943104 CREB binding protein isoform a [Homo sapiens] 82 1e-14
>gi|91718902 myeloid/lymphoid or mixed-lineage leukemia 3 [Homo
sapiens]
Length = 4911
Score = 1.006e+04 bits (26115), Expect = 0.0
Identities = 4911/4911 (100%), Positives = 4911/4911 (100%)
Query: 1 MSSEEDKSVEQPQPPPPPPEEPGAPAPSPAAADKRPRGRPRKDGASPFQRARKKPRSRGK 60
MSSEEDKSVEQPQPPPPPPEEPGAPAPSPAAADKRPRGRPRKDGASPFQRARKKPRSRGK
Sbjct: 1 MSSEEDKSVEQPQPPPPPPEEPGAPAPSPAAADKRPRGRPRKDGASPFQRARKKPRSRGK 60
Query: 61 TAVEDEDSMDGLETTETETIVETEIKEQSAEEDAEAEVDNSKQLIPTLQRSVSEESANSL 120
TAVEDEDSMDGLETTETETIVETEIKEQSAEEDAEAEVDNSKQLIPTLQRSVSEESANSL
Sbjct: 61 TAVEDEDSMDGLETTETETIVETEIKEQSAEEDAEAEVDNSKQLIPTLQRSVSEESANSL 120
Query: 121 VSVGVEAKISEQLCAFCYCGEKSSLGQGDLKQFRITPGFILPWRNQPSNKKDIDDNSNGT 180
VSVGVEAKISEQLCAFCYCGEKSSLGQGDLKQFRITPGFILPWRNQPSNKKDIDDNSNGT
Sbjct: 121 VSVGVEAKISEQLCAFCYCGEKSSLGQGDLKQFRITPGFILPWRNQPSNKKDIDDNSNGT 180
Query: 181 YEKMQNSAPRKQRGQRKERSPQQNIVSCVSVSTQTASDDQAGKLWDELSLVGLPDAIDIQ 240
YEKMQNSAPRKQRGQRKERSPQQNIVSCVSVSTQTASDDQAGKLWDELSLVGLPDAIDIQ
Sbjct: 181 YEKMQNSAPRKQRGQRKERSPQQNIVSCVSVSTQTASDDQAGKLWDELSLVGLPDAIDIQ 240
Query: 241 ALFDSTGTCWAHHRCVEWSLGVCQMEEPLLVNVDKAVVSGSTERCAFCKHLGATIKCCEE 300
ALFDSTGTCWAHHRCVEWSLGVCQMEEPLLVNVDKAVVSGSTERCAFCKHLGATIKCCEE
Sbjct: 241 ALFDSTGTCWAHHRCVEWSLGVCQMEEPLLVNVDKAVVSGSTERCAFCKHLGATIKCCEE 300
Query: 301 KCTQMYHYPCAAGAGTFQDFSHIFLLCPEHIDQAPERSKEDANCAVCDSPGDLLDQFFCT 360
KCTQMYHYPCAAGAGTFQDFSHIFLLCPEHIDQAPERSKEDANCAVCDSPGDLLDQFFCT
Sbjct: 301 KCTQMYHYPCAAGAGTFQDFSHIFLLCPEHIDQAPERSKEDANCAVCDSPGDLLDQFFCT 360
Query: 361 TCGQHYHGMCLDIAVTPLKRAGWQCPECKVCQNCKQSGEDSKMLVCDTCDKGYHTFCLQP 420
TCGQHYHGMCLDIAVTPLKRAGWQCPECKVCQNCKQSGEDSKMLVCDTCDKGYHTFCLQP
Sbjct: 361 TCGQHYHGMCLDIAVTPLKRAGWQCPECKVCQNCKQSGEDSKMLVCDTCDKGYHTFCLQP 420
Query: 421 VMKSVPTNGWKCKNCRICIECGTRSSSQWHHNCLICDNCYQQQDNLCPFCGKCYHPELQK 480
VMKSVPTNGWKCKNCRICIECGTRSSSQWHHNCLICDNCYQQQDNLCPFCGKCYHPELQK
Sbjct: 421 VMKSVPTNGWKCKNCRICIECGTRSSSQWHHNCLICDNCYQQQDNLCPFCGKCYHPELQK 480
Query: 481 DMLHCNMCKRWVHLECDKPTDHELDTQLKEEYICMYCKHLGAEMDRLQPGEEVEIAELTT 540
DMLHCNMCKRWVHLECDKPTDHELDTQLKEEYICMYCKHLGAEMDRLQPGEEVEIAELTT
Sbjct: 481 DMLHCNMCKRWVHLECDKPTDHELDTQLKEEYICMYCKHLGAEMDRLQPGEEVEIAELTT 540
Query: 541 DYNNEMEVEGPEDQMVFSEQAANKDVNGQESTPGIVPDAVQVHTEEQQKSHPSESLDTDS 600
DYNNEMEVEGPEDQMVFSEQAANKDVNGQESTPGIVPDAVQVHTEEQQKSHPSESLDTDS
Sbjct: 541 DYNNEMEVEGPEDQMVFSEQAANKDVNGQESTPGIVPDAVQVHTEEQQKSHPSESLDTDS 600
Query: 601 LLIAVSSQHTVNTELEKQISNEVDSEDLKMSSEVKHICGEDQIEDKMEVTENIEVVTHQI 660
LLIAVSSQHTVNTELEKQISNEVDSEDLKMSSEVKHICGEDQIEDKMEVTENIEVVTHQI
Sbjct: 601 LLIAVSSQHTVNTELEKQISNEVDSEDLKMSSEVKHICGEDQIEDKMEVTENIEVVTHQI 660
Query: 661 TVQQEQLQLLEEPETVVSREESRPPKLVMESVTLPLETLVSPHEESISLCPEEQLVIERL 720
TVQQEQLQLLEEPETVVSREESRPPKLVMESVTLPLETLVSPHEESISLCPEEQLVIERL
Sbjct: 661 TVQQEQLQLLEEPETVVSREESRPPKLVMESVTLPLETLVSPHEESISLCPEEQLVIERL 720
Query: 721 QGEKEQKENSELSTGLMDSEMTPTIEGCVKDVSYQGGKSIKLSSETESSFSSSADISKAD 780
QGEKEQKENSELSTGLMDSEMTPTIEGCVKDVSYQGGKSIKLSSETESSFSSSADISKAD
Sbjct: 721 QGEKEQKENSELSTGLMDSEMTPTIEGCVKDVSYQGGKSIKLSSETESSFSSSADISKAD 780
Query: 781 VSSSPTPSSDLPSHDMLHNYPSALSSSAGNIMPTTYISVTPKIGMGKPAITKRKFSPGRP 840
VSSSPTPSSDLPSHDMLHNYPSALSSSAGNIMPTTYISVTPKIGMGKPAITKRKFSPGRP
Sbjct: 781 VSSSPTPSSDLPSHDMLHNYPSALSSSAGNIMPTTYISVTPKIGMGKPAITKRKFSPGRP 840
Query: 841 RSKQGAWSTHNTVSPPSWSPDISEGREIFKPRQLPGSAIWSIKVGRGSGFPGKRRPRGAG 900
RSKQGAWSTHNTVSPPSWSPDISEGREIFKPRQLPGSAIWSIKVGRGSGFPGKRRPRGAG
Sbjct: 841 RSKQGAWSTHNTVSPPSWSPDISEGREIFKPRQLPGSAIWSIKVGRGSGFPGKRRPRGAG 900
Query: 901 LSGRGGRGRSKLKSGIGAVVLPGVSTADISSNKDDEENSMHNTVVLFSSSDKFTLNQDMC 960
LSGRGGRGRSKLKSGIGAVVLPGVSTADISSNKDDEENSMHNTVVLFSSSDKFTLNQDMC
Sbjct: 901 LSGRGGRGRSKLKSGIGAVVLPGVSTADISSNKDDEENSMHNTVVLFSSSDKFTLNQDMC 960
Query: 961 VVCGSFGQGAEGRLLACSQCGQCYHPYCVSIKITKVVLSKGWRCLECTVCEACGKATDPG 1020
VVCGSFGQGAEGRLLACSQCGQCYHPYCVSIKITKVVLSKGWRCLECTVCEACGKATDPG
Sbjct: 961 VVCGSFGQGAEGRLLACSQCGQCYHPYCVSIKITKVVLSKGWRCLECTVCEACGKATDPG 1020
Query: 1021 RLLLCDDCDISYHTYCLDPPLQTVPKGGWKCKWCVWCRHCGATSAGLRCEWQNNYTQCAP 1080
RLLLCDDCDISYHTYCLDPPLQTVPKGGWKCKWCVWCRHCGATSAGLRCEWQNNYTQCAP
Sbjct: 1021 RLLLCDDCDISYHTYCLDPPLQTVPKGGWKCKWCVWCRHCGATSAGLRCEWQNNYTQCAP 1080
Query: 1081 CASLSSCPVCYRNYREEDLILQCRQCDRWMHAVCQNLNTEEEVENVADIGFDCSMCRPYM 1140
CASLSSCPVCYRNYREEDLILQCRQCDRWMHAVCQNLNTEEEVENVADIGFDCSMCRPYM
Sbjct: 1081 CASLSSCPVCYRNYREEDLILQCRQCDRWMHAVCQNLNTEEEVENVADIGFDCSMCRPYM 1140
Query: 1141 PASNVPSSDCCESSLVAQIVTKVKELDPPKTYTQDGVCLTESGMTQLQSLTVTVPRRKRS 1200
PASNVPSSDCCESSLVAQIVTKVKELDPPKTYTQDGVCLTESGMTQLQSLTVTVPRRKRS
Sbjct: 1141 PASNVPSSDCCESSLVAQIVTKVKELDPPKTYTQDGVCLTESGMTQLQSLTVTVPRRKRS 1200
Query: 1201 KPKLKLKIINQNSVAVLQTPPDIQSEHSRDGEMDDSREGELMDCDGKSESSPEREAVDDE 1260
KPKLKLKIINQNSVAVLQTPPDIQSEHSRDGEMDDSREGELMDCDGKSESSPEREAVDDE
Sbjct: 1201 KPKLKLKIINQNSVAVLQTPPDIQSEHSRDGEMDDSREGELMDCDGKSESSPEREAVDDE 1260
Query: 1261 TKGVEGTDGVKKRKRKPYRPGIGGFMVRQRSRTGQGKTKRSVIRKDSSGSISEQLPCRDD 1320
TKGVEGTDGVKKRKRKPYRPGIGGFMVRQRSRTGQGKTKRSVIRKDSSGSISEQLPCRDD
Sbjct: 1261 TKGVEGTDGVKKRKRKPYRPGIGGFMVRQRSRTGQGKTKRSVIRKDSSGSISEQLPCRDD 1320
Query: 1321 GWSEQLPDTLVDESVSVTESTEKIKKRYRKRKNKLEETFPAYLQEAFFGKDLLDTSRQSK 1380
GWSEQLPDTLVDESVSVTESTEKIKKRYRKRKNKLEETFPAYLQEAFFGKDLLDTSRQSK
Sbjct: 1321 GWSEQLPDTLVDESVSVTESTEKIKKRYRKRKNKLEETFPAYLQEAFFGKDLLDTSRQSK 1380
Query: 1381 ISLDNLSEDGAQLLYKTNMNTGFLDPSLDPLLSSSSAPTKSGTHGPADDPLADISEVLNT 1440
ISLDNLSEDGAQLLYKTNMNTGFLDPSLDPLLSSSSAPTKSGTHGPADDPLADISEVLNT
Sbjct: 1381 ISLDNLSEDGAQLLYKTNMNTGFLDPSLDPLLSSSSAPTKSGTHGPADDPLADISEVLNT 1440
Query: 1441 DDDILGIISDDLAKSVDHSDIGPVTDDPSSLPQPNVNQSSRPLSEEQLDGILSPELDKMV 1500
DDDILGIISDDLAKSVDHSDIGPVTDDPSSLPQPNVNQSSRPLSEEQLDGILSPELDKMV
Sbjct: 1441 DDDILGIISDDLAKSVDHSDIGPVTDDPSSLPQPNVNQSSRPLSEEQLDGILSPELDKMV 1500
Query: 1501 TDGAILGKLYKIPELGGKDVEDLFTAVLSPANTQPTPLPQPPPPTQLLPIHNQDAFSRMP 1560
TDGAILGKLYKIPELGGKDVEDLFTAVLSPANTQPTPLPQPPPPTQLLPIHNQDAFSRMP
Sbjct: 1501 TDGAILGKLYKIPELGGKDVEDLFTAVLSPANTQPTPLPQPPPPTQLLPIHNQDAFSRMP 1560
Query: 1561 LMNGLIGSSPHLPHNSLPPGSGLGTFSAIAQSSYPDARDKNSAFNPMASDPNNSWTSSAP 1620
LMNGLIGSSPHLPHNSLPPGSGLGTFSAIAQSSYPDARDKNSAFNPMASDPNNSWTSSAP
Sbjct: 1561 LMNGLIGSSPHLPHNSLPPGSGLGTFSAIAQSSYPDARDKNSAFNPMASDPNNSWTSSAP 1620
Query: 1621 TVEGENDTMSNAQRSTLKWEKEEALGEMATVAPVLYTNINFPNLKEEFPDWTTRVKQIAK 1680
TVEGENDTMSNAQRSTLKWEKEEALGEMATVAPVLYTNINFPNLKEEFPDWTTRVKQIAK
Sbjct: 1621 TVEGENDTMSNAQRSTLKWEKEEALGEMATVAPVLYTNINFPNLKEEFPDWTTRVKQIAK 1680
Query: 1681 LWRKASSQERAPYVQKARDNRAALRINKVQMSNDSMKRQQQQDSIDPSSRIDSELFKDPL 1740
LWRKASSQERAPYVQKARDNRAALRINKVQMSNDSMKRQQQQDSIDPSSRIDSELFKDPL
Sbjct: 1681 LWRKASSQERAPYVQKARDNRAALRINKVQMSNDSMKRQQQQDSIDPSSRIDSELFKDPL 1740
Query: 1741 KQRESEHEQEWKFRQQMRQKSKQQAKIEATQKLEQVKNEQQQQQQQQFGSQHLLVQSGSD 1800
KQRESEHEQEWKFRQQMRQKSKQQAKIEATQKLEQVKNEQQQQQQQQFGSQHLLVQSGSD
Sbjct: 1741 KQRESEHEQEWKFRQQMRQKSKQQAKIEATQKLEQVKNEQQQQQQQQFGSQHLLVQSGSD 1800
Query: 1801 TPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAPPPPPAPS 1860
TPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAPPPPPAPS
Sbjct: 1801 TPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAPPPPPAPS 1860
Query: 1861 RIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNSA 1920
RIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNSA
Sbjct: 1861 RIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNSA 1920
Query: 1921 APVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTDQFPK 1980
APVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTDQFPK
Sbjct: 1921 APVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTDQFPK 1980
Query: 1981 SLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDSGP 2040
SLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDSGP
Sbjct: 1981 SLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDSGP 2040
Query: 2041 GPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLT 2100
GPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLT
Sbjct: 2041 GPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLT 2100
Query: 2101 PHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYS 2160
PHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYS
Sbjct: 2101 PHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYS 2160
Query: 2161 QPPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQ 2220
QPPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQ
Sbjct: 2161 QPPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQ 2220
Query: 2221 PPATPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPPG 2280
PPATPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPPG
Sbjct: 2221 PPATPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPPG 2280
Query: 2281 PGLSDTFSRVSPSAARDPYDQSPMTPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSNS 2340
PGLSDTFSRVSPSAARDPYDQSPMTPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSNS
Sbjct: 2281 PGLSDTFSRVSPSAARDPYDQSPMTPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSNS 2340
Query: 2341 PMHSQGQQFSGVSQLPGPVPTSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKKI 2400
PMHSQGQQFSGVSQLPGPVPTSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKKI
Sbjct: 2341 PMHSQGQQFSGVSQLPGPVPTSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKKI 2400
Query: 2401 AGRQEKGSQDSPAVPHPGPLQHWQPENVNQAFTRPPPPYPGNIRSPVAPPLGPRYAVFPK 2460
AGRQEKGSQDSPAVPHPGPLQHWQPENVNQAFTRPPPPYPGNIRSPVAPPLGPRYAVFPK
Sbjct: 2401 AGRQEKGSQDSPAVPHPGPLQHWQPENVNQAFTRPPPPYPGNIRSPVAPPLGPRYAVFPK 2460
Query: 2461 DQRGPYPPDVASMGMRPHGFRFGFPGGSHGTMPSQERFLVPPQQIQGSGVSPQLRRSVSV 2520
DQRGPYPPDVASMGMRPHGFRFGFPGGSHGTMPSQERFLVPPQQIQGSGVSPQLRRSVSV
Sbjct: 2461 DQRGPYPPDVASMGMRPHGFRFGFPGGSHGTMPSQERFLVPPQQIQGSGVSPQLRRSVSV 2520
Query: 2521 DMPRPLNNSQMNNPVGLPQHFSPQSLPVQQHNILGQAYIELRHRAPDGRQRLPFSAPPGS 2580
DMPRPLNNSQMNNPVGLPQHFSPQSLPVQQHNILGQAYIELRHRAPDGRQRLPFSAPPGS
Sbjct: 2521 DMPRPLNNSQMNNPVGLPQHFSPQSLPVQQHNILGQAYIELRHRAPDGRQRLPFSAPPGS 2580
Query: 2581 VVEASSNLRHGNFIPRPDFPGPRHTDPMRRPPQGLPNQLPVHPDLEQVPPSQQEQGHSVH 2640
VVEASSNLRHGNFIPRPDFPGPRHTDPMRRPPQGLPNQLPVHPDLEQVPPSQQEQGHSVH
Sbjct: 2581 VVEASSNLRHGNFIPRPDFPGPRHTDPMRRPPQGLPNQLPVHPDLEQVPPSQQEQGHSVH 2640
Query: 2641 SSSMVMRTLNHPLGGEFSEAPLSTSVPSETTSDNLQITTQPSDGLEEKLDSDDPSVKELD 2700
SSSMVMRTLNHPLGGEFSEAPLSTSVPSETTSDNLQITTQPSDGLEEKLDSDDPSVKELD
Sbjct: 2641 SSSMVMRTLNHPLGGEFSEAPLSTSVPSETTSDNLQITTQPSDGLEEKLDSDDPSVKELD 2700
Query: 2701 VKDLEGVEVKDLDDEDLENLNLDTEDGKVVELDTLDNLETNDPNLDDLLRSGEFDIIAYT 2760
VKDLEGVEVKDLDDEDLENLNLDTEDGKVVELDTLDNLETNDPNLDDLLRSGEFDIIAYT
Sbjct: 2701 VKDLEGVEVKDLDDEDLENLNLDTEDGKVVELDTLDNLETNDPNLDDLLRSGEFDIIAYT 2760
Query: 2761 DPELDMGDKKSMFNEELDLPIDDKLDNQCVSVEPKKKEQENKTLVLSDKHSPQKKSTVTN 2820
DPELDMGDKKSMFNEELDLPIDDKLDNQCVSVEPKKKEQENKTLVLSDKHSPQKKSTVTN
Sbjct: 2761 DPELDMGDKKSMFNEELDLPIDDKLDNQCVSVEPKKKEQENKTLVLSDKHSPQKKSTVTN 2820
Query: 2821 EVKTEVLSPNSKVESKCETEKNDENKDNVDTPCSQASAHSDLNDGEKTSLHPCDPDLFEK 2880
EVKTEVLSPNSKVESKCETEKNDENKDNVDTPCSQASAHSDLNDGEKTSLHPCDPDLFEK
Sbjct: 2821 EVKTEVLSPNSKVESKCETEKNDENKDNVDTPCSQASAHSDLNDGEKTSLHPCDPDLFEK 2880
Query: 2881 RTNRETAGPSANVIQASTQLPAQDVINSCGITGSTPVLSSLLANEKSDNSDIRPSGSPPP 2940
RTNRETAGPSANVIQASTQLPAQDVINSCGITGSTPVLSSLLANEKSDNSDIRPSGSPPP
Sbjct: 2881 RTNRETAGPSANVIQASTQLPAQDVINSCGITGSTPVLSSLLANEKSDNSDIRPSGSPPP 2940
Query: 2941 PTLPASPSNHVSSLPPFIAPPGRVLDNAMNSNVTVVSRVNHVFSQGVQVNPGLIPGQSTV 3000
PTLPASPSNHVSSLPPFIAPPGRVLDNAMNSNVTVVSRVNHVFSQGVQVNPGLIPGQSTV
Sbjct: 2941 PTLPASPSNHVSSLPPFIAPPGRVLDNAMNSNVTVVSRVNHVFSQGVQVNPGLIPGQSTV 3000
Query: 3001 NHSLGTGKPATQTGPQTSQSGTSSMSGPQQLMIPQTLAQQNRERPLLLEEQPLLLQDLLD 3060
NHSLGTGKPATQTGPQTSQSGTSSMSGPQQLMIPQTLAQQNRERPLLLEEQPLLLQDLLD
Sbjct: 3001 NHSLGTGKPATQTGPQTSQSGTSSMSGPQQLMIPQTLAQQNRERPLLLEEQPLLLQDLLD 3060
Query: 3061 QERQEQQQQRQMQAMIRQRSEPFFPNIDFDAITDPIMKAKMVALKGINKVMAQNNLGMPP 3120
QERQEQQQQRQMQAMIRQRSEPFFPNIDFDAITDPIMKAKMVALKGINKVMAQNNLGMPP
Sbjct: 3061 QERQEQQQQRQMQAMIRQRSEPFFPNIDFDAITDPIMKAKMVALKGINKVMAQNNLGMPP 3120
Query: 3121 MVMSRFPFMGQVVTGTQNSEGQNLGPQAIPQDGSITHQISRPNPPNFGPGFVNDSQRKQY 3180
MVMSRFPFMGQVVTGTQNSEGQNLGPQAIPQDGSITHQISRPNPPNFGPGFVNDSQRKQY
Sbjct: 3121 MVMSRFPFMGQVVTGTQNSEGQNLGPQAIPQDGSITHQISRPNPPNFGPGFVNDSQRKQY 3180
Query: 3181 EEWLQETQQLLQMQQKYLEEQIGAHRKSKKALSAKQRTAKKAGREFPEEDAEQLKHVTEQ 3240
EEWLQETQQLLQMQQKYLEEQIGAHRKSKKALSAKQRTAKKAGREFPEEDAEQLKHVTEQ
Sbjct: 3181 EEWLQETQQLLQMQQKYLEEQIGAHRKSKKALSAKQRTAKKAGREFPEEDAEQLKHVTEQ 3240
Query: 3241 QSMVQKQLEQIRKQQKEHAELIEDYRIKQQQQCAMAPPTMMPSVQPQPPLIPGATPPTMS 3300
QSMVQKQLEQIRKQQKEHAELIEDYRIKQQQQCAMAPPTMMPSVQPQPPLIPGATPPTMS
Sbjct: 3241 QSMVQKQLEQIRKQQKEHAELIEDYRIKQQQQCAMAPPTMMPSVQPQPPLIPGATPPTMS 3300
Query: 3301 QPTFPMVPQQLQHQQHTTVISGHTSPVRMPSLPGWQPNSAPAHLPLNPPRIQPPIAQLPI 3360
QPTFPMVPQQLQHQQHTTVISGHTSPVRMPSLPGWQPNSAPAHLPLNPPRIQPPIAQLPI
Sbjct: 3301 QPTFPMVPQQLQHQQHTTVISGHTSPVRMPSLPGWQPNSAPAHLPLNPPRIQPPIAQLPI 3360
Query: 3361 KTCTPAPGTVSNANPQSGPPPRVEFDDNNPFSESFQERERKERLREQQERQRIQLMQEVD 3420
KTCTPAPGTVSNANPQSGPPPRVEFDDNNPFSESFQERERKERLREQQERQRIQLMQEVD
Sbjct: 3361 KTCTPAPGTVSNANPQSGPPPRVEFDDNNPFSESFQERERKERLREQQERQRIQLMQEVD 3420
Query: 3421 RQRALQQRMEMEQHGMVGSEISSSRTSVSQIPFYSSDLPCDFMQPLGPLQQSPQHQQQMG 3480
RQRALQQRMEMEQHGMVGSEISSSRTSVSQIPFYSSDLPCDFMQPLGPLQQSPQHQQQMG
Sbjct: 3421 RQRALQQRMEMEQHGMVGSEISSSRTSVSQIPFYSSDLPCDFMQPLGPLQQSPQHQQQMG 3480
Query: 3481 QVLQQQNIQQGSINSPSTQTFMQTNERRQVGPPSFVPDSPSIPVGSPNFSSVKQGHGNLS 3540
QVLQQQNIQQGSINSPSTQTFMQTNERRQVGPPSFVPDSPSIPVGSPNFSSVKQGHGNLS
Sbjct: 3481 QVLQQQNIQQGSINSPSTQTFMQTNERRQVGPPSFVPDSPSIPVGSPNFSSVKQGHGNLS 3540
Query: 3541 GTSFQQSPVRPSFTPALPAAPPVANSSLPCGQDSTITHGHSYPGSTQSLIQLYSDIIPEE 3600
GTSFQQSPVRPSFTPALPAAPPVANSSLPCGQDSTITHGHSYPGSTQSLIQLYSDIIPEE
Sbjct: 3541 GTSFQQSPVRPSFTPALPAAPPVANSSLPCGQDSTITHGHSYPGSTQSLIQLYSDIIPEE 3600
Query: 3601 KGKKKRTRKKKRDDDAESTKAPSTPHSDITAPPTPGISETTSTPAVSTPSELPQQADQES 3660
KGKKKRTRKKKRDDDAESTKAPSTPHSDITAPPTPGISETTSTPAVSTPSELPQQADQES
Sbjct: 3601 KGKKKRTRKKKRDDDAESTKAPSTPHSDITAPPTPGISETTSTPAVSTPSELPQQADQES 3660
Query: 3661 VEPVGPSTPNMAAGQLCTELENKLPNSDFSQATPNQQTYANSEVDKLSMETPAKTEEIKL 3720
VEPVGPSTPNMAAGQLCTELENKLPNSDFSQATPNQQTYANSEVDKLSMETPAKTEEIKL
Sbjct: 3661 VEPVGPSTPNMAAGQLCTELENKLPNSDFSQATPNQQTYANSEVDKLSMETPAKTEEIKL 3720
Query: 3721 EKAETESCPGQEEPKLEEQNGSKVEGNAVACPVSSAQSPPHSAGAPAAKGDSGNELLKHL 3780
EKAETESCPGQEEPKLEEQNGSKVEGNAVACPVSSAQSPPHSAGAPAAKGDSGNELLKHL
Sbjct: 3721 EKAETESCPGQEEPKLEEQNGSKVEGNAVACPVSSAQSPPHSAGAPAAKGDSGNELLKHL 3780
Query: 3781 LKNKKSSSLLNQKPEGSICSEDDCTKDNKLVEKQNPAEGLQTLGAQMQGGFGCGNQLPKT 3840
LKNKKSSSLLNQKPEGSICSEDDCTKDNKLVEKQNPAEGLQTLGAQMQGGFGCGNQLPKT
Sbjct: 3781 LKNKKSSSLLNQKPEGSICSEDDCTKDNKLVEKQNPAEGLQTLGAQMQGGFGCGNQLPKT 3840
Query: 3841 DGGSETKKQRSKRTQRTGEKAAPRSKKRKKDEEEKQAMYSSTDTFTHLKQQNNLSNPPTP 3900
DGGSETKKQRSKRTQRTGEKAAPRSKKRKKDEEEKQAMYSSTDTFTHLKQQNNLSNPPTP
Sbjct: 3841 DGGSETKKQRSKRTQRTGEKAAPRSKKRKKDEEEKQAMYSSTDTFTHLKQQNNLSNPPTP 3900
Query: 3901 PASLPPTPPPMACQKMANGFATTEELAGKAGVLVSHEVTKTLGPKPFQLPFRPQDDLLAR 3960
PASLPPTPPPMACQKMANGFATTEELAGKAGVLVSHEVTKTLGPKPFQLPFRPQDDLLAR
Sbjct: 3901 PASLPPTPPPMACQKMANGFATTEELAGKAGVLVSHEVTKTLGPKPFQLPFRPQDDLLAR 3960
Query: 3961 ALAQGPKTVDVPASLPTPPHNNQEELRIQDHCGDRDTPDSFVPSSSPESVVGVEVSRYPD 4020
ALAQGPKTVDVPASLPTPPHNNQEELRIQDHCGDRDTPDSFVPSSSPESVVGVEVSRYPD
Sbjct: 3961 ALAQGPKTVDVPASLPTPPHNNQEELRIQDHCGDRDTPDSFVPSSSPESVVGVEVSRYPD 4020
Query: 4021 LSLVKEEPPEPVPSPIIPILPSTAGKSSESRRNDIKTEPGTLYFASPFGPSPNGPRSGLI 4080
LSLVKEEPPEPVPSPIIPILPSTAGKSSESRRNDIKTEPGTLYFASPFGPSPNGPRSGLI
Sbjct: 4021 LSLVKEEPPEPVPSPIIPILPSTAGKSSESRRNDIKTEPGTLYFASPFGPSPNGPRSGLI 4080
Query: 4081 SVAITLHPTAAENISSVVAAFSDLLHVRIPNSYEVSSAPDVPSMGLVSSHRINPGLEYRQ 4140
SVAITLHPTAAENISSVVAAFSDLLHVRIPNSYEVSSAPDVPSMGLVSSHRINPGLEYRQ
Sbjct: 4081 SVAITLHPTAAENISSVVAAFSDLLHVRIPNSYEVSSAPDVPSMGLVSSHRINPGLEYRQ 4140
Query: 4141 HLLLRGPPPGSANPPRLVSSYRLKQPNVPFPPTSNGLSGYKDSSHGIAESAALRPQWCCH 4200
HLLLRGPPPGSANPPRLVSSYRLKQPNVPFPPTSNGLSGYKDSSHGIAESAALRPQWCCH
Sbjct: 4141 HLLLRGPPPGSANPPRLVSSYRLKQPNVPFPPTSNGLSGYKDSSHGIAESAALRPQWCCH 4200
Query: 4201 CKVVILGSGVRKSFKDLTLLNKDSRESTKRVEKDIVFCSNNCFILYSSTAQAKNSENKES 4260
CKVVILGSGVRKSFKDLTLLNKDSRESTKRVEKDIVFCSNNCFILYSSTAQAKNSENKES
Sbjct: 4201 CKVVILGSGVRKSFKDLTLLNKDSRESTKRVEKDIVFCSNNCFILYSSTAQAKNSENKES 4260
Query: 4261 IPSLPQSPMRETPSKAFHQYSNNISTLDVHCLPQLPEKASPPASPPIAFPPAFEAAQVEA 4320
IPSLPQSPMRETPSKAFHQYSNNISTLDVHCLPQLPEKASPPASPPIAFPPAFEAAQVEA
Sbjct: 4261 IPSLPQSPMRETPSKAFHQYSNNISTLDVHCLPQLPEKASPPASPPIAFPPAFEAAQVEA 4320
Query: 4321 KPDELKVTVKLKPRLRAVHGGFEDCRPLNKKWRGMKWKKWSIHIVIPKGTFKPPCEDEID 4380
KPDELKVTVKLKPRLRAVHGGFEDCRPLNKKWRGMKWKKWSIHIVIPKGTFKPPCEDEID
Sbjct: 4321 KPDELKVTVKLKPRLRAVHGGFEDCRPLNKKWRGMKWKKWSIHIVIPKGTFKPPCEDEID 4380
Query: 4381 EFLKKLGTSLKPDPVPKDYRKCCFCHEEGDGLTDGPARLLNLDLDLWVHLNCALWSTEVY 4440
EFLKKLGTSLKPDPVPKDYRKCCFCHEEGDGLTDGPARLLNLDLDLWVHLNCALWSTEVY
Sbjct: 4381 EFLKKLGTSLKPDPVPKDYRKCCFCHEEGDGLTDGPARLLNLDLDLWVHLNCALWSTEVY 4440
Query: 4441 ETQAGALINVELALRRGLQMKCVFCHKTGATSGCHRFRCTNIYHFTCAIKAQCMFFKDKT 4500
ETQAGALINVELALRRGLQMKCVFCHKTGATSGCHRFRCTNIYHFTCAIKAQCMFFKDKT
Sbjct: 4441 ETQAGALINVELALRRGLQMKCVFCHKTGATSGCHRFRCTNIYHFTCAIKAQCMFFKDKT 4500
Query: 4501 MLCPMHKPKGIHEQELSYFAVFRRVYVQRDEVRQIASIVQRGERDHTFRVGSLIFHTIGQ 4560
MLCPMHKPKGIHEQELSYFAVFRRVYVQRDEVRQIASIVQRGERDHTFRVGSLIFHTIGQ
Sbjct: 4501 MLCPMHKPKGIHEQELSYFAVFRRVYVQRDEVRQIASIVQRGERDHTFRVGSLIFHTIGQ 4560
Query: 4561 LLPQQMQAFHSPKALFPVGYEASRLYWSTRYANRRCRYLCSIEEKDGRPVFVIRIVEQGH 4620
LLPQQMQAFHSPKALFPVGYEASRLYWSTRYANRRCRYLCSIEEKDGRPVFVIRIVEQGH
Sbjct: 4561 LLPQQMQAFHSPKALFPVGYEASRLYWSTRYANRRCRYLCSIEEKDGRPVFVIRIVEQGH 4620
Query: 4621 EDLVLSDISPKGVWDKILEPVACVRKKSEMLQLFPAYLKGEDLFGLTVSAVARIAESLPG 4680
EDLVLSDISPKGVWDKILEPVACVRKKSEMLQLFPAYLKGEDLFGLTVSAVARIAESLPG
Sbjct: 4621 EDLVLSDISPKGVWDKILEPVACVRKKSEMLQLFPAYLKGEDLFGLTVSAVARIAESLPG 4680
Query: 4681 VEACENYTFRYGRNPLMELPLAVNPTGCARSEPKMSAHVKRFVLRPHTLNSTSTSKSFQS 4740
VEACENYTFRYGRNPLMELPLAVNPTGCARSEPKMSAHVKRFVLRPHTLNSTSTSKSFQS
Sbjct: 4681 VEACENYTFRYGRNPLMELPLAVNPTGCARSEPKMSAHVKRFVLRPHTLNSTSTSKSFQS 4740
Query: 4741 TVTGELNAPYSKQFVHSKSSQYRKMKTEWKSNVYLARSRIQGLGLYAARDIEKHTMVIEY 4800
TVTGELNAPYSKQFVHSKSSQYRKMKTEWKSNVYLARSRIQGLGLYAARDIEKHTMVIEY
Sbjct: 4741 TVTGELNAPYSKQFVHSKSSQYRKMKTEWKSNVYLARSRIQGLGLYAARDIEKHTMVIEY 4800
Query: 4801 IGTIIRNEVANRKEKLYESQNRGVYMFRMDNDHVIDATLTGGPARYINHSCAPNCVAEVV 4860
IGTIIRNEVANRKEKLYESQNRGVYMFRMDNDHVIDATLTGGPARYINHSCAPNCVAEVV
Sbjct: 4801 IGTIIRNEVANRKEKLYESQNRGVYMFRMDNDHVIDATLTGGPARYINHSCAPNCVAEVV 4860
Query: 4861 TFERGHKIIISSSRRIQKGEELCYDYKFDFEDDQHKIPCHCGAVNCRKWMN 4911
TFERGHKIIISSSRRIQKGEELCYDYKFDFEDDQHKIPCHCGAVNCRKWMN
Sbjct: 4861 TFERGHKIIISSSRRIQKGEELCYDYKFDFEDDQHKIPCHCGAVNCRKWMN 4911
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 1088 bits (2813), Expect = 0.0
Identities = 754/2040 (36%), Positives = 1025/2040 (50%), Gaps = 270/2040 (13%)
Query: 2986 GVQVNPGLI-----PGQSTVNHSLGTGKPATQTGPQTSQSGTSSMSGPQQLMIPQTLAQQ 3040
G+++ PG + PG +N +L Q Q G S++GP P LA +
Sbjct: 3654 GLRLTPGGMALPGQPGGPFLNTALA------QQQQQQHSGGAGSLAGPSGGFFPGNLALR 3707
Query: 3041 N--------RERPLLLEEQPLLLQDLLDQERQEQQQQRQMQAMIR-QRSEPFFPNIDFDA 3091
+ +ER L L++Q + L L Q++Q+QQQQ+ + + Q+ + P + +
Sbjct: 3708 SLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQ 3767
Query: 3092 ITDPIMKAKMVALKGINKVMAQNNLGMPPMVMSRFPFMGQVVTGTQNSEGQNLGPQAIPQ 3151
P + M ++ Q PP QV Q G LGPQ +
Sbjct: 3768 ALGPKPQGLMPP-SSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGA-LGPQGPHR 3825
Query: 3152 DGSITHQ--ISRPNPPNFGPGFVNDS--QRKQYEEWLQETQQLLQMQQKYLEEQIGAHRK 3207
+T +S P G G + +Q ++ Q QQ +L++ + +H
Sbjct: 3826 QVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSG 3885
Query: 3208 SKKALSAKQRTAKKAGREFPEEDAEQLKHVTEQQSMVQKQLEQIRKQQKEHAELIEDYRI 3267
K + + ++ ++ + +QL+ +QQ Q+QL+Q + QQ++ + ++
Sbjct: 3886 QPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQ--- 3942
Query: 3268 KQQQQCAMAPPTMMPSVQPQPPLIPGATPPT----MSQPTFPMVPQQLQHQQHTTVISGH 3323
+QQQQ + Q Q ++Q + PQQ Q QQ
Sbjct: 3943 QQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMP 4002
Query: 3324 TSPVRMPSLPGWQPNSAPAHLPLNPPRIQPPIAQLPIKTCTPAPGTVSNANPQSGP---- 3379
P++ S PG L P + Q + + T + Q GP
Sbjct: 4003 AKPLQHFSSPG----------ALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIG 4052
Query: 3380 -PPRVEFDDNNPFSESFQERERKERLREQQERQRIQLMQEVDRQRALQQRMEME------ 3432
P + S + ++ Q + Q L + + QQ+ ++
Sbjct: 4053 TTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAG 4112
Query: 3433 --QHGMVGSEISSSRTSVSQIPFYSSDLPCDFMQPLGPLQQSPQHQQQMGQVLQQQNIQQ 3490
HG +GS SS +SV + QP L P Q QQ
Sbjct: 4113 GGSHGQLGSGSSSEASSVPHL----------LAQPSVSLGDQPGSMTQNLLGPQQ----- 4157
Query: 3491 GSINSPSTQTFMQTNERRQVGPPSFVPDSPSIPVGSPNFSSVKQGHGNLSGTSFQQSPVR 3550
P + MQ N Q P V S G +V Q L G + +R
Sbjct: 4158 -----PMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLR 4212
Query: 3551 ---PSFTPALPAAPPVANSSLPCGQDSTITHGHSYPGSTQSLIQLYSDIIPEEKGKKKRT 3607
P L A + L Q T + PG+ S +Q P+ G
Sbjct: 4213 HLSPQQQQQLQAL--LMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQ 4270
Query: 3608 RKKKRDDDAEST-----KAPSTPHSDITAP------PTPGISETTSTPAVSTPSELPQQA 3656
++ A + P+ P + T P PTP S S PS+LP +
Sbjct: 4271 TGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPS---SPQEPKRPSQLPSPS 4327
Query: 3657 DQESVE----PVGPSTP--------------NMAAGQLCTELENK------LPNSDFSQA 3692
Q E P P TP + AA QL L +K P++
Sbjct: 4328 SQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQ 4387
Query: 3693 TPNQQTYANSEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVEGNAVACP 3752
P Q + +D+++ + + ++ +++ +EEP K E N P
Sbjct: 4388 KPEQSSLVPGHLDQVNGQVVPEASQLSIKQEP------REEPCALGAQSVKREANGE--P 4439
Query: 3753 VSSAQSPPHSAGAPAAKGDSGNELLKHLLKNKKSSSLLNQKPEGSICSEDDCTKDNKLVE 3812
+ + + H A + ++G+ LL+ LL+ K + EG + +E + D+KL
Sbjct: 4440 IGAPGTSNHLLLA-GPRSEAGHLLLQKLLRAKNVQLSTGRGSEG-LRAEINGHIDSKLAG 4497
Query: 3813 KQNPAEGLQTLGAQMQGGFGCGNQLPKTDGGSETK-KQRSKRTQRTGEKAAPRSKKRKKD 3871
+ +G + + + S+ R K + G +A+ K+ K
Sbjct: 4498 LEQKLQGTPSNKEDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQ 4557
Query: 3872 EEE------------------------------------KQAMYSSTDTFTHLKQQNNLS 3895
E A+ + D ++ L +NNLS
Sbjct: 4558 ELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLS 4617
Query: 3896 NPPTPPASLPPTPPPMACQKMANGFATTEELAGKAGVLVSHEVTKTLGPKPFQLPFRPQD 3955
NPPTPP+SLPPTPPP QKM NG +EE LG P
Sbjct: 4618 NPPTPPSSLPPTPPPSVQQKMVNGVTPSEE----------------LGEHPKDAASARDS 4661
Query: 3956 DLLARALAQGPKTVDVPASLPTPPHNNQEELRIQDHCGDRDTPDSFVPSSSPESVVGVEV 4015
+ R ++ K++D+ A+LPTPPHN E++R++ D D+PDS VP+SSPES++G E
Sbjct: 4662 ERALRDTSE-VKSLDLLAALPTPPHNQTEDVRMESD-EDSDSPDSIVPASSPESILGEEA 4719
Query: 4016 SRYPDLSLVKEEPPEPVPSPIIPILPSTAGKSSESRRNDIKTEPGTLYFASPFGPSP--- 4072
R+P L + E + SP+IP++P ++S D K G L P G P
Sbjct: 4720 PRFPHLGSGRWEQEDRALSPVIPLIP----RASIPVFPDTKPY-GALGLEVP-GKLPVTT 4773
Query: 4073 -NGPRSGLISVAITLHPTAAENISSVVAAFSDLLHVRIPNSYEVSSAPDVPSMGLVSSHR 4131
+ +SV +T+ AA+N++ V+ A ++LL ++IPNSYEV P+ P+
Sbjct: 4774 WEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEV-LFPESPA-------- 4824
Query: 4132 INPGLEYRQHLLLRGPPPGSANPPRLVSSYRLKQPNVPFPPTSNGLSGYKDSSHGIAESA 4191
G E P G A P GL G +S
Sbjct: 4825 -RAGTE---------PKKGEAEGP---------------GGKEKGLEG---------KSP 4850
Query: 4192 ALRPQWCCHCKVVILGSGVRKSFKDLTLLNKDSRESTKRVEKDIVFCSNNCFILYSSTAQ 4251
P W V+ G ++ L+LL ++S + + +N + S
Sbjct: 4851 DTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPP 4910
Query: 4252 AKNSENKESIPSLPQSPMRETPSKAFHQYSNNISTLDVHCLPQLPEKASPPASPPIAFPP 4311
+ PS P SP+ +P+ L +LP P A PP+ P
Sbjct: 4911 PEE-------PSPPPSPLAPSPASP-----------PTEPLVELP--TEPLAEPPVPSPL 4950
Query: 4312 AFEAAQVEAKPDELKVTVKLKPRLRAVHGGFEDCRPLNKKWRGMKWKKWSIHIVIPKGTF 4371
++ A+P KPR R G + P KKW+G++WK+ + + I KG+
Sbjct: 4951 PLASSPESARP---------KPRARPPEEGEDSRPPRLKKWKGVRWKRLRLLLTIQKGSG 5001
Query: 4372 KPPCEDEIDEFLKKLGTSLKPDPVPKDYRKCCFCHEEGDGLTDGPARLLNLDLDLWVHLN 4431
+ E E+ EF+++LGT+L+PD VP+D R+CCFCHEEGDG TDGPARLLNLDLDLWVHLN
Sbjct: 5002 RQEDEREVAEFMEQLGTALRPDKVPRDMRRCCFCHEEGDGATDGPARLLNLDLDLWVHLN 5061
Query: 4432 CALWSTEVYETQAGALINVELALRRGLQMKCVFCHKTGATSGCHRFRCTNIYHFTCAIKA 4491
CALWSTEVYETQ GAL+NVE+AL RGL KC C +TGATS C+R RC N+YHF CAI+A
Sbjct: 5062 CALWSTEVYETQGGALMNVEVALHRGLLTKCSLCQRTGATSSCNRMRCPNVYHFACAIRA 5121
Query: 4492 QCMFFKDKTMLCPMHKPKGIHEQELSYFAVFRRVYVQRDEVRQIASIVQRGERDHTFRVG 4551
+CMFFKDKTMLCPMHK KG EQELS FAVFRRVY++RDEV+QIASI+QRGER H FRVG
Sbjct: 5122 KCMFFKDKTMLCPMHKIKGPCEQELSSFAVFRRVYIERDEVKQIASIIQRGERLHMFRVG 5181
Query: 4552 SLIFHTIGQLLPQQMQAFHSPKALFPVGYEASRLYWSTRYANRRCRYLCSIEEKDGRPVF 4611
L+FH IGQLLP QM FHS AL+PVGYEA+R+YWS R NRRC Y CSI E +GRP F
Sbjct: 5182 GLVFHAIGQLLPHQMADFHSATALYPVGYEATRIYWSLRTNNRRCCYRCSIGENNGRPEF 5241
Query: 4612 VIRIVEQGHEDLVLSDISPKGVWDKILEPVACVRKKSEMLQLFPAYLKGEDLFGLTVSAV 4671
VI+++EQG EDLV +D SP+ VW++I+EPVA +RK+++ML+LFP YLKGE+LFGLTV AV
Sbjct: 5242 VIKVIEQGLEDLVFTDASPQAVWNRIIEPVAAMRKEADMLRLFPEYLKGEELFGLTVHAV 5301
Query: 4672 ARIAESLPGVEACENYTFRYGRNPLMELPLAVNPTGCARSEPKMSAHVKRFVLRPHTLNS 4731
RIAESLPGVE+C+NY FRYGR+PLMELPL +NPTGCARSEPK+ H K RPHTLNS
Sbjct: 5302 LRIAESLPGVESCQNYLFRYGRHPLMELPLMINPTGCARSEPKILTHYK----RPHTLNS 5357
Query: 4732 TSTSKSFQSTVTGELNAPYSKQFVHSKSSQYRKMKTEWKSNVYLARSRIQGLGLYAARDI 4791
TS SK++QST TGE N PYSKQFVHSKSSQYR+++TEWK+NVYLARSRIQGLGLYAA+D+
Sbjct: 5358 TSMSKAYQSTFTGETNTPYSKQFVHSKSSQYRRLRTEWKNNVYLARSRIQGLGLYAAKDL 5417
Query: 4792 EKHTMVIEYIGTIIRNEVANRKEKLYESQNRGVYMFRMDNDHVIDATLTGGPARYINHSC 4851
EKHTMVIEYIGTIIRNEVANR+EK+YE QNRG+YMFR++N+HVIDATLTGGPARYINHSC
Sbjct: 5418 EKHTMVIEYIGTIIRNEVANRREKIYEEQNRGIYMFRINNEHVIDATLTGGPARYINHSC 5477
Query: 4852 APNCVAEVVTFERGHKIIISSSRRIQKGEELCYDYKFDFEDDQHKIPCHCGAVNCRKWMN 4911
APNCVAEVVTF++ KIII SSRRI KGEEL YDY+FDFEDDQHKIPCHCGA NCRKWMN
Sbjct: 5478 APNCVAEVVTFDKEDKIIIISSRRIPKGEELTYDYQFDFEDDQHKIPCHCGAWNCRKWMN 5537
Score = 1057 bits (2733), Expect = 0.0
Identities = 941/2933 (32%), Positives = 1296/2933 (44%), Gaps = 568/2933 (19%)
Query: 870 KPRQLPGSAIWSIKVGRGSGFPGKRRPRGAGLSGRGGRGRSKLKSGIGAVVLPGVSTADI 929
K R+ A IK GR S FPG+RRPRG GRG RGR++LKS ++ V+ D
Sbjct: 1288 KGRRRSSPARSRIKQGRSSSFPGRRRPRGGAHGGRG-RGRARLKSTASSIETLVVADIDS 1346
Query: 930 SSNKDDEE---NSMHNTVVLFSSSDKFTLNQDMCVVCGSFGQGAEGRLLACSQCGQCYHP 986
S +K++EE ++M NTVVLFS++DKF L QDMCVVCGSFG+GAEG LLACSQC QCYHP
Sbjct: 1347 SPSKEEEEEDDDTMQNTVVLFSNTDKFVLMQDMCVVCGSFGRGAEGHLLACSQCSQCYHP 1406
Query: 987 YCVSIKITKVVLSKGWRCLECTVCEACGKATDPGRLLLCDDCDISYHTYCLDPPLQTVPK 1046
YCV+ KITKV+L KGWRC+EC VCE CG+A+DP RLLLCDDCDISYHTYCLDPPL TVPK
Sbjct: 1407 YCVNSKITKVMLLKGWRCVECIVCEVCGQASDPSRLLLCDDCDISYHTYCLDPPLLTVPK 1466
Query: 1047 GGWKCKWCVWCRHCGATSAGLRCEWQNNYTQCAPCASLSSCPVCYRNYREEDLILQCRQC 1106
GGWKCKWCV C CGA S G CEWQN+YT C PCASL +CP+C+ Y EEDL++QCR C
Sbjct: 1467 GGWKCKWCVSCMQCGAASPGFHCEWQNSYTHCGPCASLVTCPICHAPYVEEDLLIQCRHC 1526
Query: 1107 DRWMHAVCQNLNTEEEVENVADIGFDCSMCRPYMPASNVPSSDCCESSLVAQIVTKVKEL 1166
+RWMHA C++L TE++VE AD GFDC C+PY+ P + LV KVKE
Sbjct: 1527 ERWMHAGCESLFTEDDVEQAADEGFDCVSCQPYVVK---PVAPVAPPELVPM---KVKEP 1580
Query: 1167 DPPKTYTQDGVCLTESGMTQLQSLTVTVPRRKRSKPKLKLKIINQNSVAVLQTPPDIQSE 1226
+ P+ + +GV LTE+GM L++LT++ P KR + + +L + + + + + +
Sbjct: 1581 E-PQYFRFEGVWLTETGMALLRNLTMS-PLHKRRQRRGRLGLPGEAGLEGSEPSDALGPD 1638
Query: 1227 HSRDGEMDDSR----EG--ELMDCDGKSES--SPEREAVDDETKGVEGTDGVKKRKRKPY 1278
+DG++D EG E M+C+ K E SP+ E G E T+ KKRKRKPY
Sbjct: 1639 DKKDGDLDTDELLKGEGGVEHMECEIKLEGPVSPDVE------PGKEETEESKKRKRKPY 1692
Query: 1279 RPGIGGFMVRQR---SRTGQGKTKRSVIRKDSSGSISEQLPCRDDGWSEQLP-DTLVDES 1334
RPGIGGFMVRQR +RT +G ++ + G E +P LP + V++S
Sbjct: 1693 RPGIGGFMVRQRKSHTRTKKGPAAQAEV-LSGDGQPDEVIPA-------DLPAEGAVEQS 1744
Query: 1335 VSVTESTEKIKKRYRKRKNKLEETFPAYLQEAFFGKDLLDTSRQSKISLDNLSEDGAQLL 1394
++ + +K ++R RK K+KLE+ FPAYLQEAFFGK+LLD SR++ ++ +
Sbjct: 1745 LAEGDEKKKQQRRGRK-KSKLEDMFPAYLQEAFFGKELLDLSRKALFAVG---------V 1794
Query: 1395 YKTNMNTGFLDPSLDPLLSSSSAPT-KSGTHGPADDPLADISEVLNTDDDILGIISDDLA 1453
+ + G D PT + G GP D + S L D G +
Sbjct: 1795 GRPSFGLGTPKAKGDGGSERKELPTSQKGDDGP--DIADEESRGLEGKADTPGPEDGGVK 1852
Query: 1454 KSVDHSDIGPVTDDPSSLPQPNVNQSSRPLSEEQLDGILSPELDKMVTDGAILGKLYKIP 1513
S PV DP P +G+LS +LD++ T+ ++P
Sbjct: 1853 AS-------PVPSDPEKPGTPG-------------EGMLSSDLDRISTE--------ELP 1884
Query: 1514 ELGGKDVEDLFTAVLSPANTQPTPLPQPPPPTQLLPIHNQDAFSRMPLMNGLIGSSPHLP 1573
++ KD++ LF VL Q P P+ + P + G LP
Sbjct: 1885 KMESKDLQQLFKDVLGSEREQHLGCGTPGLEGSRTPL-------QRPFLQG------GLP 1931
Query: 1574 HNSLPPGSGLGTFSAIAQSSYPDARDKNSAFNPMASDPNNSWTSS---------APTVEG 1624
+LP S + ++ + QS + D+R++ F+P +P++ WT S PT EG
Sbjct: 1932 LGNLPSSSPMDSYPGLCQSPFLDSRERGGFFSPEPGEPDSPWTGSGGTTPSTPTTPTTEG 1991
Query: 1625 ENDTMSNAQRSTLKWEKEEALGEMATVAPVLYTNINFPNLKEEFPDWTTRVKQIAKLWRK 1684
E D +S QRS +WEK+E LG+++T++PVLY NINFPNLK+++PDW++R KQI KLWRK
Sbjct: 1992 EGDGLSYNQRSLQRWEKDEELGQLSTISPVLYANINFPNLKQDYPDWSSRCKQIMKLWRK 2051
Query: 1685 ASSQERAPYVQKARDNRAALRINKVQMSNDSMKRQQQQDSIDPSSRIDSELFKDPLKQRE 1744
+ ++APY+QKA+DNRAA RINKVQ KQ E
Sbjct: 2052 VPAADKAPYLQKAKDNRAAHRINKVQ------------------------------KQAE 2081
Query: 1745 SEHEQEWKFRQQMRQKSKQQAKIEATQKLEQVKNEQQQQQQQQFGSQHLLVQSGSDTPSS 1804
S+ ++ K R+ + + + + + F GS T +
Sbjct: 2082 SQINKQTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIF--------IGSPTTPA 2133
Query: 1805 GIQSP----LTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVF-------VKPQAP 1853
G+ + L P G+ P ELF K PP P S D F ++P+ P
Sbjct: 2134 GLSTSADGFLKPPAGS---VPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFP 2190
Query: 1854 PPPP----------APSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAK--- 1900
PP AP++ P+ + S+ QP PG+ +P +P DP+ K
Sbjct: 2191 TAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTP-DPFLKPRC 2249
Query: 1901 ----MVGTPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPSP-------- 1948
+ P P VG ++ P+ + P + L++ + SP
Sbjct: 2250 PSLDNLAVPESPGVGGG----KASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLG 2305
Query: 1949 VRDLCSSSTTNNDPYAKPPD------TPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAG 2002
D SS T K PD TPR + P+S GL P + P A
Sbjct: 2306 FVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVE--PQSPGLGLRP------QEPPPAQA 2357
Query: 2003 TSDHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQ 2062
+ P D+F+ D YA+P LTP P QPPP P +
Sbjct: 2358 LA---PSPPSHPDIFRPGSYTDPYAQPPLTPRP------------QPPP----PESCCAL 2398
Query: 2063 ASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTI 2122
R L DP+ R +P+ +QS+ SQ PLTP P E+F PS P T
Sbjct: 2399 PPRSLPSDPFSRVPASPQ-------SQSS---SQSPLTPRPLSAEAFC-PS-----PVT- 2441
Query: 2123 SRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPR 2182
R S DPYS+PP P+ + DP++ PRP + +
Sbjct: 2442 PRFQSPDPYSRPPSRPQ---------------SRDPFAPLHKPPRPQPPEVAFKAGSLAH 2486
Query: 2183 PSTQTDLF-----VTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFTRSS 2237
S F P P PP R + + P+ R + S
Sbjct: 2487 TSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPS 2546
Query: 2238 MTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQT---------PRPPGPGLSDTFS 2288
+ PV P P + G PGP + P + + T P GP T
Sbjct: 2547 LKPPVPQPGLPPPHGINSHFG---PGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGE 2603
Query: 2289 RVSPSAARDPYDQSPMTPRSQSD--SFGTSQTAHDVADQPRPGSEGSFCASSNSPMHSQG 2346
S R P P P S G SQ + + + G+ SS + G
Sbjct: 2604 SYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPG 2663
Query: 2347 QQFSGVSQLPGPVPTSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKKIAGRQEK 2406
Q G+S ++Q + EK RQRQ+LRE++++QQ Q+ RQEK
Sbjct: 2664 TQDPGMS------------------GLSQTELEKQRQRQRLRELLIRQQIQRNTL-RQEK 2704
Query: 2407 GSQDSPAVPHPGPLQHWQPENVNQAF---TRPPPPYPGN------IRSPVA----PPLGP 2453
+ + A GP W E + AF +R P+ G + P + P LGP
Sbjct: 2705 ETA-AAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGP 2763
Query: 2454 RYAVFPKDQRGPYPPDVASMGMRPHGFRFGFPGGSH---------GTMPSQERFLVPPQQ 2504
FP D R PP A+ R GGS G++P Q++ QQ
Sbjct: 2764 --GSFPSDDRLSRPPPPATPSSMDVNSR-QLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQ 2820
Query: 2505 IQGSGVSPQLRRSVSVDMPRPLNNSQMNNPVGLPQHFSPQSLPVQQHNILGQA----YIE 2560
Q + + +R ++S P +G P LP + G A +IE
Sbjct: 2821 QQATAAT-SMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIE 2879
Query: 2561 LRHRAPDGRQRLPFSAPPGSVVEASSNLRHGNFIPRPDFPGPRHTDPMRRPPQGL----P 2616
LRH G P G+ + F P + DP R P+GL
Sbjct: 2880 LRHNVQKG------LGPGGTPFPGQGPPQRPRFYPVSE-------DPHRLAPEGLRGLAV 2926
Query: 2617 NQLPVHPDLEQVPPSQQEQGHSVHSSSMVMRTLNHPLGGEFSEAPLSTSVPSETTSDNLQ 2676
+ LP P PP+ E +S+H + + P G E P S++ L+
Sbjct: 2927 SGLP--PQKPSAPPA-PELNNSLHPTPHT-KGPTLPTGLELVNRPPSSTELGRPNPLALE 2982
Query: 2677 ITTQPSDGLEEKLDSDDPSVKELDVKDLEGVEVKDLDDEDLENLNLDTEDGK-VVELDTL 2735
P + + +LD D + K L+ DDE+L +L L + K EL TL
Sbjct: 2983 AGKLPCE--DPELDDDFDAHKALE------------DDEELAHLGLGVDVAKGDDELGTL 3028
Query: 2736 DNLETNDPNLDDLLRSGEFDIIAYTDPELDMGDKKSMFNEELDL--PIDDKLDNQCV--S 2791
+NLETNDP+LDDLL EFD++AYTDPELD GDKK +FNE L L ++K + + +
Sbjct: 3029 ENLETNDPHLDDLLNGDEFDLLAYTDPELDTGDKKDIFNEHLRLVESANEKAEREALLRG 3088
Query: 2792 VEPKKKEQENKTLVLSDKHSPQKKSTVTNEVKTEVLSPNSKVESKCETEKNDENKDNVDT 2851
VEP E + +D P + ++V EVK +V
Sbjct: 3089 VEPGPLGPEERPPPAADASEP-RLASVLPEVKPKV------------------------- 3122
Query: 2852 PCSQASAHSDLNDGEKTSLHPCDPDLFEKRTNRETAGPSANVIQASTQLPAQDVINSCGI 2911
E+ HP P F T + P+AN + + P Q ++ S
Sbjct: 3123 --------------EEGGRHP-SPCQFTIATPKVEPAPAANSLGLGLK-PGQSMMGSRDT 3166
Query: 2912 TGSTPVLSSLLANEKSDNSDIRPSGSPPPPTLPASP---------------SNHVSSLPP 2956
T SS + ++ + +G PP L SP + +LP
Sbjct: 3167 RMGTGPFSS--SGHTAEKASFGATGGPPAHLLTPSPLSGPGGSSLLEKFELESGALTLPG 3224
Query: 2957 FIAPPGRVLDNAMNSNVT------VVSRVNHVFSQ-------GVQVNPGLIPGQSTVNHS 3003
A G LD +S V + + H + Q+ P Q HS
Sbjct: 3225 GPAASGDELDKMESSLVASELPLLIEDLLEHEKKELQKKQQLSAQLQPAQQQQQQQQQHS 3284
Query: 3004 LGTGKPATQTGPQTSQSGTSSMSGPQQLM-----------IPQTL--------AQQNRER 3044
L + Q + + S++G QQ + +PQ L A Q R
Sbjct: 3285 LLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQPGLPQPLMPTQPPAHALQQRLA 3344
Query: 3045 PLLL-----------------------EEQPLLLQDLLDQERQEQQQQRQMQAMIRQRSE 3081
P + QP+L Q + + Q AM +Q +
Sbjct: 3345 PSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPVLSQKPMGTMPPSMCMKPQQLAMQQQLAN 3404
Query: 3082 PFFPNIDFDA-----ITDPIMKAKMVALKGINKVMAQNNLGMPP-MVMSRFPFMGQVVTG 3135
FFP+ D D I DPI KAKMVALKGI KVMAQ ++G+ P M + + Q ++G
Sbjct: 3405 SFFPDTDLDKFAAEDIIDPIAKAKMVALKGIKKVMAQGSIGVAPGMNRQQVSLLAQRLSG 3464
Query: 3136 TQNSEGQNLGPQAIPQDGSITHQIS-RPNPPNFGPGFVNDSQRKQYEEWLQETQQLLQMQ 3194
+S+ QN Q+ S RPNPP F G +N++ ++QYEEWL TQQLLQMQ
Sbjct: 3465 GPSSDLQNHVAAGSGQERSAGDPSQPRPNPPTFAQGVINEADQRQYEEWLFHTQQLLQMQ 3524
Query: 3195 QKYLEEQIGAHRKSKKALSAKQRTAKKAGREFPEEDAEQLKHVTEQQSMVQKQLEQIRKQ 3254
K LEEQIG HRKS+KAL AKQRTAKKAGREFPE DAE+LK VTEQQS +QKQL+Q+RKQ
Sbjct: 3525 LKVLEEQIGVHRKSRKALCAKQRTAKKAGREFPEADAEKLKLVTEQQSKIQKQLDQVRKQ 3584
Query: 3255 QKEHAELIEDYRIKQQQQCAMAPPTMMPSVQPQPPLIPGATPPTMSQPTFPMVPQQLQHQ 3314
QKEH L+ +YR KQQQQ Q Q QQ Q Q
Sbjct: 3585 QKEHTNLMAEYRNKQQQQ------------QQQ---------------------QQQQQQ 3611
Query: 3315 QHTTV--ISGHTSPVRMPSLPGWQPNSAPAHLPLNPP-------RIQPPIAQLPIKTCTP 3365
QH+ V +S SP + LPG P PP R+ P LP + P
Sbjct: 3612 QHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGP 3671
Query: 3366 --------------APGTVSNANPQSG-PPPRVEFDDNNPFSESFQERERKERLREQQER 3410
+ G S A P G P + P S QER+ Q ++
Sbjct: 3672 FLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQL------QLQQ 3725
Query: 3411 QRIQLMQEVDRQRALQQRMEMEQH--GMVGSEISSS-----RTSVSQIPFYSSDLPCDFM 3463
QR+QL Q++ +Q QQ+ + +QH G V + +T+ + P +P
Sbjct: 3726 QRMQLAQKLQQQ---QQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSH 3782
Query: 3464 QPLGPLQQSPQHQQ----QMG----QVLQQQNIQQGSINSPSTQTFMQTNERRQVGPPSF 3515
Q L Q SPQ Q +G VLQQQ+ P Q M + R + P
Sbjct: 3783 QGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLM--TQSRVLSSPQL 3840
Query: 3516 VPDSPS------IPVGSPNFSSVKQGHGNLSGTS-FQQSPVRPSFTPALPAAP 3561
+ Q G+++G S QQS + S P L A P
Sbjct: 3841 AQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQP 3893
Score = 295 bits (755), Expect = 8e-79
Identities = 174/481 (36%), Positives = 236/481 (49%), Gaps = 86/481 (17%)
Query: 60 KTAVEDEDS---MDGLETTETETIVETEIKEQSAEEDAEAEVDNSKQLIPTLQRSVSEES 116
K A ED+DS DG +E + E+++ EV P LQ + + S
Sbjct: 5 KLAGEDKDSEPAADGPAASEDPSATESDLPNPHV-----GEVSVLSSGSPRLQETPQDCS 59
Query: 117 ANSLVSVGVEAKISEQLCAFCYCGEKSSLGQGDLKQFRITPGFILPWRNQPSNKKDIDDN 176
+ + CA C CGE S GQ +L++F + W P
Sbjct: 60 GGPV-----------RRCALCNCGEPSLHGQRELRRFELP----FDWPRCPV-------- 96
Query: 177 SNGTYEKMQNSAPRKQRGQRKERSPQQNIVSCVSVSTQTASDDQAGKLWDELSLVGLPDA 236
+P G + P + +LS +G P+
Sbjct: 97 ----------VSPGGSPGPNEAVLPSE-----------------------DLSQIGFPEG 123
Query: 237 IDIQALFDSTGTCWAHHRCVEWSLGVCQMEEPLLVNVDKAVVSGSTERCAFCKHLGATIK 296
+ L + G+CWAHH C WS GV E P L VDKA+ SG ++RC+ C LGA+I
Sbjct: 124 LTPAHLGEPGGSCWAHHWCAAWSAGVWGQEGPELCGVDKAIFSGISQRCSHCTRLGASIP 183
Query: 297 CCEEKCTQMYHYPCAAGAGTFQDFSHIFLLCPEHIDQAPERSKEDANCAVCDSPGDLLDQ 356
C C ++YH+PCA +G+F + LLCPEH + A E+A CAVC+ PG+L D
Sbjct: 184 CRSPGCPRLYHFPCATASGSFLSMKTLQLLCPEHSEGAAYL--EEARCAVCEGPGELCDL 241
Query: 357 FFCTTCGQHYHGMCLDIAVTPLKRAGWQCPECKVCQNCKQSGEDSKMLVCDTCDKGYHTF 416
FFCT+CG HYHG CLD A+T KRAGWQCPECKVCQ C++ G DSKMLVC+TCDKGYHTF
Sbjct: 242 FFCTSCGHHYHGACLDTALTARKRAGWQCPECKVCQACRKPGNDSKMLVCETCDKGYHTF 301
Query: 417 CLQPVMKSVPTNGWKCKNCRICIECGTRS-----SSQWHHNCLICDNCYQQQDNLCPFCG 471
CL+P M+ +P + WKCK CR+C CG S +S+W N +C C++ Q G
Sbjct: 302 CLKPPMEELPAHSWKCKACRVCRACGAGSAELNPNSEWFENYSLCHRCHKAQG------G 355
Query: 472 KCYHPELQKDMLHCNMCKRWVHLE-CDKPTDHELDTQLKEEYICMYCKHLGAEMDRLQPG 530
+ ++ H +C R+ E D PTD E D Y+ + G + +QP
Sbjct: 356 QTIRSVAEQ---HTPVCSRFSPPEPGDTPTD-EPDAL----YVACQGQPKGGHVTSMQPK 407
Query: 531 E 531
E
Sbjct: 408 E 408
Score = 131 bits (330), Expect = 1e-29
Identities = 72/219 (32%), Positives = 111/219 (50%), Gaps = 23/219 (10%)
Query: 344 CAVCDSPGDLLDQFF--CTTCGQHYHGMCLDIAVTPLKRA-GWQCPECKVCQNCKQSGED 400
C VC S G + C+ C Q YH C++ +T + GW+C EC VC+ C Q+ +
Sbjct: 1380 CVVCGSFGRGAEGHLLACSQCSQCYHPYCVNSKITKVMLLKGWRCVECIVCEVCGQASDP 1439
Query: 401 SKMLVCDTCDKGYHTFCLQPVMKSVPTNGWKCKNCRICIECGTRSSS---QWHHNCLICD 457
S++L+CD CD YHT+CL P + +VP GWKCK C C++CG S +W ++ C
Sbjct: 1440 SRLLLCDDCDISYHTYCLDPPLLTVPKGGWKCKWCVSCMQCGAASPGFHCEWQNSYTHCG 1499
Query: 458 NCYQQQDNLCPFCGKCYHPELQKDML-HCNMCKRWVHLECDKP-TDHELDTQLKEEYICM 515
C CP C+ P +++D+L C C+RW+H C+ T+ +++ E + C+
Sbjct: 1500 PCASLV--TCPI---CHAPYVEEDLLIQCRHCERWMHAGCESLFTEDDVEQAADEGFDCV 1554
Query: 516 YCKHLGAEMDRLQPGEEVEIAELTTDYNNEMEVEGPEDQ 554
C QP +A + M+V+ PE Q
Sbjct: 1555 SC----------QPYVVKPVAPVAPPELVPMKVKEPEPQ 1583
Score = 116 bits (290), Expect = 6e-25
Identities = 54/129 (41%), Positives = 73/129 (56%), Gaps = 5/129 (3%)
Query: 955 LNQDMCVVCGSFGQGAEGRLLACSQCGQCYHPYCVSIKITKVVLSKGWRCLECTVCEACG 1014
L + C VC G+ + L C+ CG YH C+ +T + GW+C EC VC+AC
Sbjct: 224 LEEARCAVCEGPGELCD--LFFCTSCGHHYHGACLDTALTARKRA-GWQCPECKVCQACR 280
Query: 1015 KATDPGRLLLCDDCDISYHTYCLDPPLQTVPKGGWKCKWCVWCRHCGATSAGL--RCEWQ 1072
K + ++L+C+ CD YHT+CL PP++ +P WKCK C CR CGA SA L EW
Sbjct: 281 KPGNDSKMLVCETCDKGYHTFCLKPPMEELPAHSWKCKACRVCRACGAGSAELNPNSEWF 340
Query: 1073 NNYTQCAPC 1081
NY+ C C
Sbjct: 341 ENYSLCHRC 349
Score = 84.0 bits (206), Expect = 3e-15
Identities = 137/609 (22%), Positives = 209/609 (34%), Gaps = 83/609 (13%)
Query: 1802 PSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTS------SDDVFVKPQAPPP 1855
PS +++PL+P P +SP F + + P PTS S P +PPP
Sbjct: 528 PSPALETPLSPPPEASPLSP--PFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPP 585
Query: 1856 PPAPSRIPIQDS-----LSQAQTSQPPSPQVFSPGSSNSR--PP---SPMDPYAKMVGTP 1905
+P P + S ++ S PP SP SR PP SPM P +
Sbjct: 586 EESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMS 645
Query: 1906 RPPPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAK 1965
PP V SR + V +P S E + P P S ++
Sbjct: 646 PPPEV----SRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPP 701
Query: 1966 PPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDS 2025
P D+P + SL L SP++ H SPR +
Sbjct: 702 PEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHL---SPRPE---------- 748
Query: 2026 YARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNF 2085
P L+P P + P P ++P LS E P L+P+P +
Sbjct: 749 --EPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQA-EGPHLSPQPEELH 805
Query: 2086 SHNQSNDPYSQP-PLTPHPAVNESFAHPSRAFSQPGTISRPTS---QDPYSQPPGTPRPV 2141
Q+ +P+ P P P + +H S +P RP +PP +PRP
Sbjct: 806 LSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRP- 864
Query: 2142 VDSYSQSSGTARSNTD-PYSQPPGTP--RPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQR 2198
+ + G + + P PPG P P +P +P P S + + +
Sbjct: 865 -EKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEP 923
Query: 2199 HSDPYAHPPGTPRPGIS--VPYSQPPA-TPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQ 2255
P PP P +S + + PPA +P + F + P + P
Sbjct: 924 SLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELEYPFGAKGDSDP-----ESPL----- 973
Query: 2256 NRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQSDSFGT 2315
P L P+ PP+ P P P + S SP P P+ P+ +
Sbjct: 974 -AAPILETPISPPPEANCTDPEPVPPMILPP-SPGSPVGPASPILMEPLPPQC------S 1025
Query: 2316 SQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPV-PTSGVTDTQNTVNMA 2374
H + Q P S+ C+ P+ +P P+ P V + +
Sbjct: 1026 PLLQHSLVPQNSPPSQ---CSPPALPL-----------SVPSPLSPIGKVVGVSDEAELH 1071
Query: 2375 QADTEKLRQ 2383
+ +TEK+ +
Sbjct: 1072 EMETEKVSE 1080
Score = 79.7 bits (195), Expect = 7e-14
Identities = 121/501 (24%), Positives = 185/501 (36%), Gaps = 66/501 (13%)
Query: 1807 QSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVK------PQAPPPPPAPS 1860
+SPL+P P SP + + P P S + + + P +PPP +P
Sbjct: 446 ESPLSPPPEESPTSPPPEASR--LSPPPEELPASPLPEALHLSRPLEESPLSPPPEESP- 502
Query: 1861 RIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNSA 1920
S PP FSP + P P + + TP PP +
Sbjct: 503 ------------LSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPP-----PEASPL 545
Query: 1921 APVENCTPLSSVSRPLQMN-ETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTDQFP 1979
+P +PLS L + A+R SP + + + P + P +P P + FP
Sbjct: 546 SPPFEESPLSPPPEELPTSPPPEASRLSPPPE----ESPMSPPPEESPMSPPPEASRLFP 601
Query: 1980 KSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDS- 2038
SP E P A + SP + + + L+P P+ S
Sbjct: 602 PFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSR 661
Query: 2039 -GPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSND----- 2092
P P ++P+ PPP + P +AS RLS P + P +P P D+ + D
Sbjct: 662 LSPPPEESPLSPPP-EESPTSPPPEAS-RLSPPPEDSPT-SPPPEDSPASPPPEDSLMSL 718
Query: 2093 PYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGTA 2152
P + PL P P P G P ++P+ +PRP + S
Sbjct: 719 PLEESPLLPLP------EEPQLCPRSEGPHLSPRPEEPHL----SPRP--EEPHLSPQAE 766
Query: 2153 RSNTDPYSQPP---GTPRPTTVDPYSQQPQ-TPRPSTQTDLFVTPVTNQRHSDPYAHPPG 2208
+ P + P P + P ++ P +P+P +L ++P T + H P P
Sbjct: 767 EPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPE---ELHLSPQTEEPHLSPVPEEPC 823
Query: 2209 -TPRPGIS--VPYSQPPATPRPRISEGFTRSSMTRPVLMPN-QDPFLQAAQNRGPALPGP 2264
+P+P S P S+ P PR E + +P L P + P + Q P P
Sbjct: 824 LSPQPEESHLSPQSEEPCL-SPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPE-ELP 881
Query: 2265 LVRPPDTCSQTPRPPGPGLSD 2285
L PP S +P P LS+
Sbjct: 882 LFPPPGEPSLSPLLGEPALSE 902
Score = 76.3 bits (186), Expect = 7e-13
Identities = 188/860 (21%), Positives = 277/860 (32%), Gaps = 218/860 (25%)
Query: 1813 QPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAP-----PPPPAPSRIPIQDS 1867
QP G+++ Q KE Q + P + + + +AP P P P P+
Sbjct: 395 QPKGGHVTSMQP--KEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPP 452
Query: 1868 LSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNSAAPVENCT 1927
++ TS PP SP PP + P P SR +P+
Sbjct: 453 PEESPTSPPPEASRLSP------PPEELPA--------SPLPEALHLSRPLEESPLSPPP 498
Query: 1928 PLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTDQFPKSLGLSRS 1987
S +S P + + + SP+ PP+ P + P S S
Sbjct: 499 EESPLSPPPESSPFSPLEESPL---------------SPPEESPPSPALETPLSPPPEAS 543
Query: 1988 PVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDS--GPGPFKT 2045
P+ S + P++ + T P P A L+P P +S P P ++
Sbjct: 544 PL-SPPFEESPLSPPPEELPTSPPPEAS--------------RLSPPPEESPMSPPPEES 588
Query: 2046 PMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLTPHPAV 2105
PM PPP +ASR P+E L+P P + PL+P P
Sbjct: 589 PMSPPP----------EASRLFP--PFEESPLSPPP-------------EESPLSPPP-- 621
Query: 2106 NESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQPPGT 2165
+ +S P P S PP P S PP
Sbjct: 622 ------------EASRLSPPPEDSPMSPPP-------------------EESPMSPPPEV 650
Query: 2166 PRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATP 2225
R + + S+ P S P++ P + PP R +S P P +P
Sbjct: 651 SRLSPLPVVSRLSPPPEES--------PLSPPPEESPTSPPPEASR--LSPPPEDSPTSP 700
Query: 2226 RPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSD 2285
P S P P +D + P LP P P C PR GP LS
Sbjct: 701 PPEDS----------PASPPPEDSLMSLPLEESPLLPLP--EEPQLC---PRSEGPHLS- 744
Query: 2286 TFSRVSPSAARDPYDQSP-MTPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSNSPMHS 2344
P + P ++PR + ++ QP E CA P S
Sbjct: 745 ------------PRPEEPHLSPRPEEPHLSPQAEEPHLSPQP---EEPCLCAVPEEPHLS 789
Query: 2345 QGQQFSGVSQLPGPVPTSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKKIAGRQ 2404
+ +S P + S T+ +++ E Q + Q ++ ++ R
Sbjct: 790 PQAEGPHLSPQPEELHLSPQTEEP---HLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRP 846
Query: 2405 EKGSQDSPAVPHP--GPLQHWQPENVNQAFTR------PPPPYPG--------NIRSPVA 2448
E+ S SP + P P PE Q PPP P + P
Sbjct: 847 EE-SHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGE 905
Query: 2449 PPLGPRYAVFPKDQRG------------PYPPDV-------ASMGMRPHGFRFGFPGGSH 2489
PPL P P G P PP + A + P G +P G+
Sbjct: 906 PPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLG-ELEYPFGAK 964
Query: 2490 GTMPSQERFLVPPQQIQGSGVSPQLRRSVSVDMPRP--LNNSQMNNPVG-----LPQHFS 2542
G + P I + +SP + + P P + +PVG L +
Sbjct: 965 GDSDPESPLAAP---ILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLP 1021
Query: 2543 PQSLPVQQHNILGQAYIELRHRAPDGRQRLPFSAPP-----GSVV----EASSNLRHGNF 2593
PQ P+ QH+++ Q + P LP S P G VV EA +
Sbjct: 1022 PQCSPLLQHSLVPQNSPPSQCSPP----ALPLSVPSPLSPIGKVVGVSDEAELHEMETEK 1077
Query: 2594 IPRPDFPG--PRHTDPMRRP 2611
+ P+ P P T P+ P
Sbjct: 1078 VSEPECPALEPSATSPLPSP 1097
Score = 61.2 bits (147), Expect = 2e-08
Identities = 37/108 (34%), Positives = 50/108 (46%), Gaps = 5/108 (4%)
Query: 4410 DGLTDGPARLLNLDLDLWVHLNCALWSTEVYETQAGALINVELALRRGLQMKCVFCHKTG 4469
+GLT PA L W H CA WS V+ + L V+ A+ G+ +C C + G
Sbjct: 122 EGLT--PAHLGEPGGSCWAHHWCAAWSAGVWGQEGPELCGVDKAIFSGISQRCSHCTRLG 179
Query: 4470 ATSGCHRFRCTNIYHFTCAIKAQCMFFKDKT--MLCPMHKPKGIHEQE 4515
A+ C C +YHF CA A F KT +LCP H + +E
Sbjct: 180 ASIPCRSPGCPRLYHFPCA-TASGSFLSMKTLQLLCPEHSEGAAYLEE 226
Score = 60.8 bits (146), Expect = 3e-08
Identities = 163/713 (22%), Positives = 239/713 (33%), Gaps = 163/713 (22%)
Query: 1924 ENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTDQFPKSLG 1983
E TP+ S P + +T + P + C + P P P+ + P
Sbjct: 363 EQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKP---- 418
Query: 1984 LSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDSGPGPF 2043
L ++ V E + P+ + PLL P P
Sbjct: 419 LGKAGVQLEPQLEAPL-------------------------NEEMPLLPP--------PE 445
Query: 2044 KTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLTPHP 2103
++P+ PPP + P +ASR LS P E PA P+ H + P + PL+P P
Sbjct: 446 ESPLSPPPE-ESPTSPPPEASR-LSPPPEELPA---SPLPEALH--LSRPLEESPLSPPP 498
Query: 2104 AVNESFAHP-SRAFSQPGTISRPTSQDPYSQPPGTP-RPVVDSYSQSSGTARSNTDPYSQ 2161
+ P S FS P + P S P +P P +++ A + P+ +
Sbjct: 499 EESPLSPPPESSPFS-------PLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEE 551
Query: 2162 PPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQP 2221
P +P P + P +P P R S P P +P P S P S P
Sbjct: 552 SPLSPPP------EELPTSPPPEAS-----------RLSPPPEESPMSPPPEES-PMSPP 593
Query: 2222 PATPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPPGP 2281
P R + F S ++ P P +A++ P P+ PP+ +P P
Sbjct: 594 PEASR--LFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVS 651
Query: 2282 GLSD--TFSRVSPSAARDPYDQSPMTPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSN 2339
LS SR+SP P ++SP++ P P
Sbjct: 652 RLSPLPVVSRLSP-----PPEESPLS--------------------PPP---------EE 677
Query: 2340 SPMHSQGQQFSGVSQLPGPVPTSGVTDTQNTVNMAQADTEKLRQRQKLREI-ILQQQQQK 2398
SP S + S +S P PTS + + A E L E +L ++
Sbjct: 678 SPT-SPPPEASRLSPPPEDSPTSPPPED----SPASPPPEDSLMSLPLEESPLLPLPEEP 732
Query: 2399 KIAGRQEKGS-QDSPAVPHPGPLQ---HWQPENVNQAFTRPPPPYPGNIRSPVAPPLGPR 2454
++ R E P PH P H P+ + P P P P P L P+
Sbjct: 733 QLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQ-AEEPHLSPQPEEPCLCAVPEEPHLSPQ 791
Query: 2455 YAVFPKDQRGPYPPDVASMGMRPHGFRFGFPGGSHGTMPSQERFLVPPQQIQGSGVSPQL 2514
A P P ++ PH P E + PQ + S +SPQ
Sbjct: 792 -AEGPHLSPQPEELHLSPQTEEPH------------LSPVPEEPCLSPQP-EESHLSPQS 837
Query: 2515 RRSVSVDMPRPLNNS-QMNNPVGLPQHFSPQSLPVQQHNILGQAYIELRHRAPDGRQRLP 2573
P + S ++ P P+ P P GQ AP+ LP
Sbjct: 838 EEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEP-------GQC------PAPE---ELP 881
Query: 2574 FSAPPGSVVEASSNLRHGNFIPRPDFPGPRHTDPMRRPPQGLPNQLPVHPDLE 2626
PPG E S + P P ++P P LP +LP+ P E
Sbjct: 882 LFPPPG---EPSLS---------PLLGEPALSEPGEPPLSPLPEELPLSPSGE 922
Score = 60.1 bits (144), Expect = 5e-08
Identities = 29/86 (33%), Positives = 42/86 (48%), Gaps = 1/86 (1%)
Query: 250 WAHHRCVEWSLGVCQMEEPLLVNVDKAVVSGSTERCAFCKHLGATIKCCEEKCTQMYHYP 309
W H C WS V + + L+NV+ A+ G +C+ C+ GAT C +C +YH+
Sbjct: 5057 WVHLNCALWSTEVYETQGGALMNVEVALHRGLLTKCSLCQRTGATSSCNRMRCPNVYHFA 5116
Query: 310 CAAGAGTFQDFSHIFLLCPEHIDQAP 335
CA A F +LCP H + P
Sbjct: 5117 CAIRA-KCMFFKDKTMLCPMHKIKGP 5141
Score = 57.4 bits (137), Expect = 3e-07
Identities = 114/479 (23%), Positives = 167/479 (34%), Gaps = 78/479 (16%)
Query: 1715 SMKRQQQQDSIDPSSRIDSELFKDPLKQRESEHEQEWKFRQQMRQKSKQQAKIEATQKLE 1774
S+++ QQQ + ++ + + +Q++ + +Q +QQ +Q+ QQ + + Q+ +
Sbjct: 3896 SLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQ---LQQQQQQQQLQQQQQQQLQQQQ 3952
Query: 1775 QVKNEQQQQQQQQFGSQHLLVQSGSDTPSSGIQSPLTPQ-------PGNGNMSPAQSFH- 1826
Q +QQQQQQQQF Q Q G S + SP Q PG P Q F
Sbjct: 3953 QQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGM-PAKPLQHFSS 4011
Query: 1827 ------------KELFTKQPPSTPTSTSSDD--------VFVKPQAPPPPPAPSRIPIQD 1866
KE T P + +T + P++ P + P
Sbjct: 4012 PGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVK-PSLS 4070
Query: 1867 SLSQAQTSQP-PSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNS-----A 1920
SQ QP P PQ P S +PP + + + G S + S A
Sbjct: 4071 GDSQLLLVQPQPQPQ---PSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEA 4127
Query: 1921 APVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTDQFPK 1980
+ V + SVS Q T N P + + NN P P+P Q +
Sbjct: 4128 SSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNN----TGPQPPKPGPVLQSGQ 4183
Query: 1981 SL-GLSRSPVVSEQTA--KGPIAAGTSDHFTKPSP----RADVFQRQ-------RIPDSY 2026
L G+ P V + A +G +A P +A + QRQ R Y
Sbjct: 4184 GLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPY 4243
Query: 2027 ARPLLTPAPLD----------SGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPA 2076
P +PL PGP P+Q + P Q RL P A
Sbjct: 4244 QEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRP-----QGPPRLPAPP---GA 4295
Query: 2077 LTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPP 2135
L+ P+ H Q P P + S P+ A P P Q P +PP
Sbjct: 4296 LSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPP 4354
Score = 50.1 bits (118), Expect = 6e-05
Identities = 42/171 (24%), Positives = 60/171 (35%), Gaps = 51/171 (29%)
Query: 980 CGQCYHPYC-------VSIKITKVVL---SKGWRCLE---CTVCEACGKATDPGRLLLCD 1026
C + YH C +S+K +++ S+G LE C VCE G+ D L C
Sbjct: 189 CPRLYHFPCATASGSFLSMKTLQLLCPEHSEGAAYLEEARCAVCEGPGELCD---LFFCT 245
Query: 1027 DCDISYHTYCLDPPLQTVPKGGWKCKWCVWCRHCGATSAGLRCEWQNNYTQCAPCASLSS 1086
C YH CLD L + GW+C C C+ C
Sbjct: 246 SCGHHYHGACLDTALTARKRAGWQCPECKVCQAC-------------------------- 279
Query: 1087 CPVCYRNYREEDLILQCRQCDRWMHAVCQNLNTEEEVENVADIGFDCSMCR 1137
R + +L C CD+ H C + +E + + C CR
Sbjct: 280 -----RKPGNDSKMLVCETCDKGYHTFC----LKPPMEELPAHSWKCKACR 321
Score = 47.0 bits (110), Expect = 5e-04
Identities = 195/917 (21%), Positives = 307/917 (33%), Gaps = 172/917 (18%)
Query: 3213 SAKQRTAKKAGREFPEEDAEQLKHVTEQQSMVQKQLEQIRKQQKEHAELIEDYRIKQQQQ 3272
S++ + K R+ P D K Q++ + +I K QK+ I KQ +
Sbjct: 2039 SSRCKQIMKLWRKVPAAD----KAPYLQKAKDNRAAHRINKVQKQAESQIN----KQTKV 2090
Query: 3273 CAMAPPTMMPSVQPQPPLIPGA--TPPTMSQPTF----PMVPQQLQHQQHTTV------I 3320
+A T P++ + P PGA +PP + PT P P L + +
Sbjct: 2091 GDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSV 2150
Query: 3321 SGHTSPVRM-----PSLPGWQPNSAPAHL----PLNP--PRIQPPIAQLPIKTCTPAPGT 3369
G SP + P +P P+ P L PL P P P P T PA
Sbjct: 2151 PGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPP 2210
Query: 3370 VSNANPQSGPPPRVEFDDNNPFSESFQERERKERLREQQERQRIQLMQEVDRQRALQQRM 3429
+ A+ + G EF P + Q L+ R +L
Sbjct: 2211 MLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKP--------------RCPSLDNLA 2256
Query: 3430 EMEQHGMVGSEISSSRTSVSQIPFYSSDLPCDFMQPLGPLQQSPQHQQQMGQVLQQQNIQ 3489
E G+ G + S S P F + L+ + N+
Sbjct: 2257 VPESPGVGGGKASEPLLS-----------PPPFGESRKALEVKKEELGASSPSYGPPNL- 2304
Query: 3490 QGSINSPSTQTFMQTNERRQVGPPSFVPDSPSIPVGSPNFSSVKQGHGNLSGTSFQQSPV 3549
G ++SPS+ T + E + PD P+ +P S V+ L G Q+ P
Sbjct: 2305 -GFVDSPSSGTHLGGLELK-------TPDVFKAPL-TPRASQVEPQSPGL-GLRPQEPPP 2354
Query: 3550 RPSFTPALPAAPPV---ANSSLPCGQDSTITHGHSYPGSTQSLIQLYSDIIPEEKGKKKR 3606
+ P+ P+ P + + + P Q P +S L +P +
Sbjct: 2355 AQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQ--PPPPESCCALPPRSLPSDPF---- 2408
Query: 3607 TRKKKRDDDAESTKAPSTPH--SDITAPPTPGISETTSTPAVSTPSELPQQADQESV--E 3662
+R S+++P TP S P+P S S P PQ D + +
Sbjct: 2409 SRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQSRDPFAPLHK 2468
Query: 3663 PVGPSTPNMA--AGQLCT------------------ELENKLPNSDFSQATPNQQTYANS 3702
P P P +A AG L EL K+P+ PN + S
Sbjct: 2469 PPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQ----PPN---FVRS 2521
Query: 3703 EVDKLSMETPAKTE-EIKLEKAETESCPGQEEPKLEEQNGSKVE---GNAVACPVSS--- 3755
+ TP+ E P +P L +G G + P S+
Sbjct: 2522 PGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYT 2581
Query: 3756 -AQSPPHSAGAPAAKGDSGNELLKHLLKNKKSSSLLNQKPEGSIC-----SEDDCTKDNK 3809
A H +G+P L + S L P+GS+ + +
Sbjct: 2582 VATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSP 2641
Query: 3810 LVEKQNPAEGLQTLGAQMQGGFGCGNQLPKTDGGSETKKQRSKRTQRTGEKAAPRSKKRK 3869
+ ++++P G+ G+ + G Q P G S+T+ ++ ++ QR E + +R
Sbjct: 2642 VEKREDPGTGM---GSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRN 2698
Query: 3870 KDEEEKQAMYSSTDTFTHLKQQNNLSNPPTPPASLPPTPPPMACQKMANG---FATTEEL 3926
+EK+ ++ + PP S P A ++++ G FA T++
Sbjct: 2699 TLRQEKETAAAA-------------AGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDK 2745
Query: 3927 AGKAGVLVSHEVTKTLGPKPFQLPFRPQDDLLARALAQG-PKTVDV-------------- 3971
+ G+ S LGP F P DD L+R P ++DV
Sbjct: 2746 SSLVGLPPSKLSGPILGPGSF-----PSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQ 2800
Query: 3972 ----PASLPTPPHNNQEELRIQDHCGDRDTPDSFVPSSSPESVVGVEVSR------YPDL 4021
P SLP Q++ Q T F S+ S G E+ R +
Sbjct: 2801 RAPYPGSLPL---QQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGI 2857
Query: 4022 SLVKEEPPEPVPSPIIP 4038
S P EPVP P P
Sbjct: 2858 STRLPGPGEPVPGPAGP 2874
Score = 45.1 bits (105), Expect = 0.002
Identities = 114/593 (19%), Positives = 190/593 (32%), Gaps = 74/593 (12%)
Query: 3465 PLGPLQQSPQHQQQMGQVLQQQNIQQGSINSPSTQTFMQTNERRQVGPPSFVPDSPSI-- 3522
P PL ++ + + + ++ ++ P + E + PP P SP++
Sbjct: 475 PASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALET 534
Query: 3523 PVGSPNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAAPPVANSSLPCGQDSTIT----- 3577
P+ P +S F++SP+ P + PP A+ P ++S ++
Sbjct: 535 PLSPPPEASPLS-------PPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEE 587
Query: 3578 HGHSYPGSTQSLIQLYSDII----PEEKGKKKRTRKKKRDDDAESTKAPSTPHSDITAPP 3633
S P L + + PEE + E + P +PP
Sbjct: 588 SPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPP 647
Query: 3634 TPGISETTSTPAVSTPSELPQQADQESVEPVGPSTPNMAAGQLCTELENKLPNSDFSQAT 3693
P +S + P VS S P+++ P++P A +L P D +
Sbjct: 648 -PEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSP------PPEDSPTSP 700
Query: 3694 PNQQTYANSEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVEGNAVACPV 3753
P + + A+ + M P + + E + CP E P L
Sbjct: 701 PPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHL----------------- 743
Query: 3754 SSAQSPPHSAGAPAAKGDSGNELLKHLLKNKKSSSLLNQKPEGSICSEDDCTKDNKLVEK 3813
S PH + P HL + L Q E +C+ + + E
Sbjct: 744 SPRPEEPHLSPRPEE---------PHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEG 794
Query: 3814 QNPAEGLQTLGAQMQGGFGCGNQLPKTDGGSETKKQRSKRTQRTGEKAAPRSKKRKKDEE 3873
+ + + L Q + +P+ S ++ Q +PR ++ E
Sbjct: 795 PHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPE 854
Query: 3874 EKQAMYSSTDTFTHLKQQNNLSNPPTPPASLPPTPPPMACQKMANGFATTEELAGKAGVL 3933
++ S K P P LP PPP G + L G+
Sbjct: 855 LEKPPLSPRPE----KPPEEPGQCPA-PEELPLFPPP--------GEPSLSPLLGEPA-- 899
Query: 3934 VSHEVTKTLGPKPFQLPFRPQDDLLARALAQGPKTVDVPASLPTPPHNNQEELRIQDHCG 3993
+S L P P +LP P + P P P P G
Sbjct: 900 LSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPD----PLPPPLSPIITAAAPPALSPLG 955
Query: 3994 DRDTPDSFVPSSSPESVVGVEVSRYPDLSLVKE---EPPEPVPSPIIPILPST 4043
+ + P S PES + + P +S E PEPVP I+P P +
Sbjct: 956 ELEYPFGAKGDSDPESPLAAPILETP-ISPPPEANCTDPEPVPPMILPPSPGS 1007
Score = 45.1 bits (105), Expect = 0.002
Identities = 101/484 (20%), Positives = 174/484 (35%), Gaps = 68/484 (14%)
Query: 1727 PSSRIDSELFKDPLKQRESEHEQEWKFRQQMRQKSKQQAKIEATQKL-EQVKNEQQQQQQ 1785
PS++ D+ K PL + ++ R+K +++ + A++ L +Q+K E
Sbjct: 4506 PSNKEDAAARK-PLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLLPL 4564
Query: 1786 QQ---FGSQHLLVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTS 1842
+ + L GS P +G QS L G+G + ++ +L TK S P +
Sbjct: 4565 TEPAITANFSLFAPFGSGCPVNG-QSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPTPP 4623
Query: 1843 SDDVFVKPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNS-RPPSPMDPYAKM 1901
S P PPP+ + + + + P + S + R S + +
Sbjct: 4624 SS------LPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLL 4677
Query: 1902 VGTPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNND 1961
P PP R S ++ + S P E+ +P S +
Sbjct: 4678 AALPTPPHNQTEDVRMESDEDSDSPDSIVPASSP----ESILGEEAPRFPHLGSGRWEQE 4733
Query: 1962 PYAKPPDTPR------PVMTDQFP-KSLGL---SRSPVVSEQTAKG-------PIAAGTS 2004
A P P PV D P +LGL + PV + + KG ++A +
Sbjct: 4734 DRALSPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAA 4793
Query: 2005 DHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQD--------- 2055
+ +IP+SY L +P +G P K + P +
Sbjct: 4794 KNLNGVMVAVAELLSMKIPNSY-EVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDT 4852
Query: 2056 ------------PYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQ----PPL 2099
P ++ LS+ E PA P ++++N SN Q PP
Sbjct: 4853 GPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPE 4912
Query: 2100 TPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPY 2159
P P + P+ ++P + PT +P ++PP P P+ + S S + P
Sbjct: 4913 EPSPPPSPLAPSPASPPTEP-LVELPT--EPLAEPP-VPSPLPLASSPESARPK----PR 4964
Query: 2160 SQPP 2163
++PP
Sbjct: 4965 ARPP 4968
Score = 42.0 bits (97), Expect = 0.015
Identities = 110/497 (22%), Positives = 167/497 (33%), Gaps = 94/497 (18%)
Query: 3275 MAPPTMMPSVQPQPPLIPGATPPT---MSQPT--FPMVPQQLQHQQHTTVISGHTSPVRM 3329
++PP P P P + PP MS P P++P + Q H SP
Sbjct: 689 LSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSP--R 746
Query: 3330 PSLPGWQPNSAPAHLPLNPPRIQPPIAQLPIKTCTPAPGTVSNANPQSGPPPRVEFDDNN 3389
P P P HL +P +P ++ P + C A + +PQ+ P
Sbjct: 747 PEEPHLSPRPEEPHL--SPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGP--------- 795
Query: 3390 PFSESFQERERKERLREQQERQRIQLMQEVDRQRALQQRMEMEQHGMVGSEISSSRTSVS 3449
+ + L Q E + + E + L + E E H SE +S
Sbjct: 796 ----HLSPQPEELHLSPQTEEPHLSPVPE---EPCLSPQPE-ESHLSPQSE----EPCLS 843
Query: 3450 QIPFYSSDLPCDFMQPLGPLQQSPQHQQQMGQVLQQQNIQQ-GSINSPSTQTFMQTNERR 3508
P S P PL P + P ++ GQ + + PS +
Sbjct: 844 PRPEESHLSPELEKPPLSPRPEKPP--EEPGQCPAPEELPLFPPPGEPSLSPLLGEPALS 901
Query: 3509 QVGPPSFVPDSPSIPVGSPNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAAPPVANSSL 3568
+ G P P +P+ SP+ G +LS P+ P +P + AA P A S L
Sbjct: 902 EPGEPPLSPLPEELPL-SPS------GEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPL 954
Query: 3569 PCGQDSTITHGHSYPGSTQSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTKAPSTPHSD 3628
G+ + K D D ES A +
Sbjct: 955 ---------------------------------GELEYPFGAKGDSDPESPLAAPILETP 981
Query: 3629 ITAPPTPGISETTSTPAVSTPSELPQQADQESVEPVGPSTPNMAAGQLCTELENKLPNSD 3688
I+ PP ++ P P LP PVGP++P + L + L +S
Sbjct: 982 ISPPPEANCTDPEPVP----PMILPPSPG----SPVGPASP-ILMEPLPPQCSPLLQHSL 1032
Query: 3689 FSQATPNQQTYANSEVDKLSMETPAK--------TEEIKLEKAETESCPGQEEPKLEEQN 3740
Q +P Q + LS+ +P ++E +L + ETE E P LE
Sbjct: 1033 VPQNSPPSQ--CSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSA 1090
Query: 3741 GSKVEG--NAVACPVSS 3755
S + ++CP S
Sbjct: 1091 TSPLPSPMGDLSCPAPS 1107
Score = 40.4 bits (93), Expect = 0.044
Identities = 123/603 (20%), Positives = 192/603 (31%), Gaps = 123/603 (20%)
Query: 1717 KRQQQQDSIDPSSRIDSELFKDPLKQRESEH--------EQEWKFRQQMRQKSKQQAKIE 1768
++ QQQ S+ S + L + + S +Q+ + +QQ + + +QQ +++
Sbjct: 3862 QQHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQ 3921
Query: 1769 ATQKLEQVK-NEQQQQQQQQFGSQHLLVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHK 1827
Q+L+Q + +QQQQQQ Q Q L Q +Q Q Q
Sbjct: 3922 QQQQLQQQQLQQQQQQQQLQQQQQQQLQQQ-----QQQLQQQQQQQQQQFQQQQQQQQMG 3976
Query: 1828 ELFTKQPPSTPTSTSSDDVFVKPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSS 1887
L + +P V + P P P L + P + G
Sbjct: 3977 LLNQSRTLLSPQQQQQQQVALGPGMPAKP-----------LQHFSSPGALGPTLLLTG-- 4023
Query: 1888 NSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPS 1947
+ + +DP T P PL+ + P E+ A P
Sbjct: 4024 --KEQNTVDPAVSSEATEGP--------------STHQGGPLAIGTTP----ESMATEPG 4063
Query: 1948 PVRDLCSSSTTNNDPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTA----KGPIAAGT 2003
V+ S + +P P + + G + V TA G + +G+
Sbjct: 4064 EVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGS 4123
Query: 2004 SDHFTK-----PSPRADVFQRQRIPDSYARPLLTP-APLDSGPGPFKTPMQPPPSSQDPY 2057
S + P + + P S + LL P P+ P T QPP
Sbjct: 4124 SSEASSVPHLLAQPSVSLGDQ---PGSMTQNLLGPQQPMLERPMQNNTGPQPPKP----- 4175
Query: 2058 GSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFS 2117
G V Q+ + L P + P Q ++ P H + + +
Sbjct: 4176 GPVLQSGQGL-------PGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQ 4228
Query: 2118 QPGTISRPTSQDPYSQPPGTP----RPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDP 2173
+ S+ Q P Q PGT + ++ Q G T P + PRP
Sbjct: 4229 RQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRP----- 4283
Query: 2174 YSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGF 2233
P+ P P L PV H P PP++P+
Sbjct: 4284 -QGPPRLPAPPGA--LSTGPVLGPVHPTP------------------PPSSPQ------- 4315
Query: 2234 TRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPS 2293
RP +P+ L P PG TP+P GP L RVSP+
Sbjct: 4316 ---EPKRPSQLPSPSSQLPTEAQLPPTHPG-----------TPKPQGPTLEPPPGRVSPA 4361
Query: 2294 AAR 2296
AA+
Sbjct: 4362 AAQ 4364
Score = 37.4 bits (85), Expect = 0.37
Identities = 45/183 (24%), Positives = 64/183 (34%), Gaps = 20/183 (10%)
Query: 1834 PPSTPTSTSSDDV--FVKPQAPPPPPAPSR------IPIQDS--LSQAQTSQPPSPQVFS 1883
PP T + V + P +P P P+ +P Q S L + Q P S
Sbjct: 984 PPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCS 1043
Query: 1884 PGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTA 1943
P + PSP+ P K+VG + + + S P ++ P M + +
Sbjct: 1044 PPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSC 1103
Query: 1944 NRPSPVRDL-----CSSSTTNNDPYAKPPDTPRPVMTDQFPKSLG--LSRSPVVSEQTAK 1996
PSP L T D P P P Q P SL L SPV+ +
Sbjct: 1104 PAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEP---GQTPGSLASELKGSPVLLDPEEL 1160
Query: 1997 GPI 1999
P+
Sbjct: 1161 APV 1163
Score = 37.0 bits (84), Expect = 0.48
Identities = 80/323 (24%), Positives = 114/323 (35%), Gaps = 73/323 (22%)
Query: 2170 TVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGIS----VPYSQPPATP 2225
TVDP T PST P+ + A PG +P +S + QP P
Sbjct: 4028 TVDPAVSSEATEGPSTHQG---GPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQP 4084
Query: 2226 RPRISEGFTRSSMTRPVLMPNQDPF-LQAAQNRGPALPGPLVRPPDT-CSQTPR---PPG 2280
+P + + P+ +P Q + G G L + S P P
Sbjct: 4085 QP------SSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPS 4138
Query: 2281 PGLSDTFSRVSPSAARDPYDQSPMTPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSNS 2340
L D ++ + Q PM R ++ G P+PG
Sbjct: 4139 VSLGDQPGSMTQNLLGP---QQPMLERPMQNNTGPQP--------PKPG----------- 4176
Query: 2341 PMHSQGQQFSGVSQLPGPVPTSGVTDTQNTVNMAQADTEKLR-----QRQKLREIILQQQ 2395
P+ GQ GV G +PT G Q + A +LR Q+Q+L+ +++Q+Q
Sbjct: 4177 PVLQSGQGLPGV----GIMPTVGQLRAQ--LQGVLAKNPQLRHLSPQQQQQLQALLMQRQ 4230
Query: 2396 QQKKIAGR-----QEKGSQDSPAV--------------PHPGPLQHWQPENVNQAFTRPP 2436
Q+ A R QE G+Q SP P GPLQ Q R P
Sbjct: 4231 LQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLP 4290
Query: 2437 PPYPGNIRSPVAPPLGPRYAVFP 2459
P PG + + P LGP + P
Sbjct: 4291 AP-PGALST--GPVLGPVHPTPP 4310
Score = 35.4 bits (80), Expect = 1.4
Identities = 60/263 (22%), Positives = 83/263 (31%), Gaps = 48/263 (18%)
Query: 2402 GRQEKGSQDSPAVPHPGPLQ-HWQPENVNQAFTRPPPPYPGNIRSPVAPPLGPRYAVFPK 2460
G+ + G S PGPLQ +P P P N P+ PP P
Sbjct: 394 GQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPP 453
Query: 2461 DQRGPYPPDVASMGMRPHGFRFGFPGGSHGTMPSQERFLVPPQQIQGSGVSPQLRRSVSV 2520
++ PP P R PP+++ S + L S +
Sbjct: 454 EESPTSPP------------------------PEASRLSPPPEELPASPLPEALHLSRPL 489
Query: 2521 DMPRPLNNSQMNNPVGLPQHFSPQSLPVQQHNILGQAYIELRHRAPDGRQRLPFSAPPGS 2580
+ PL+ +P+ P SP S P+++ + P P S PP
Sbjct: 490 E-ESPLSPPPEESPLSPPPESSPFS-PLEESPLSPP-----EESPPSPALETPLSPPP-- 540
Query: 2581 VVEASSNLRHGNFIPRPDFPGPRHTDPMRRPPQGLPNQLPVHPDLEQVPPSQQEQGHSVH 2640
EAS P P P P+ PP+ LP P PP +
Sbjct: 541 --EAS-----------PLSP-PFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPE 586
Query: 2641 SSSMVMRTLNHPLGGEFSEAPLS 2663
S M L F E+PLS
Sbjct: 587 ESPMSPPPEASRLFPPFEESPLS 609
Score = 33.9 bits (76), Expect = 4.1
Identities = 61/278 (21%), Positives = 98/278 (35%), Gaps = 44/278 (15%)
Query: 2328 PGSEGSFCASSNSPMHSQGQQFSGVSQLPGP----------VPTSGVTDTQNTVNMAQAD 2377
PG G ++ Q Q G L GP + + G Q
Sbjct: 3665 PGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQERQLQLQ 3724
Query: 2378 TEKLRQRQKLREIILQQQQQKKIAGRQ--EKGSQDSPAVP-----HPGPLQHWQPEN--- 2427
++++ QKL++ QQQQQ+ + G+ ++ Q P V P P P +
Sbjct: 3725 QQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQG 3784
Query: 2428 -VNQAFTRPPPPYPGNIRSP------------VAPPLGPRYAVFPKDQRGPYPPDVASMG 2474
+ Q + PP P + P P GP V R P +A G
Sbjct: 3785 LLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQG 3844
Query: 2475 MRPHGFRFGFPGGSHGTMPSQERFLVPPQQIQGSGVSPQLRRSVSVDMPRPLNNSQMNNP 2534
G G T Q++ QQ +G+S L++S+ +P ++Q P
Sbjct: 3845 Q-------GLMGHRLVTAQQQQQQQQHQQQGSMAGLS-HLQQSLMSHSGQPKLSAQ---P 3893
Query: 2535 VGLPQHFSPQSLPVQQHNILGQAYIELRHRAPDGRQRL 2572
+G Q Q QQ + Q +L+ + +Q+L
Sbjct: 3894 MGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQL 3931
Score = 32.7 bits (73), Expect = 9.1
Identities = 50/192 (26%), Positives = 71/192 (36%), Gaps = 20/192 (10%)
Query: 3896 NPPTPPASLPPTPPPMACQKMANGFATT------EEL----AGKAGVLVSHEVTKTLGPK 3945
+PP+P P +PPP A ++ F + EEL +A L + P
Sbjct: 526 SPPSPALETPLSPPPEA-SPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPP 584
Query: 3946 PFQLPFRPQDDL--LARALAQGPKTVDVPASLPTPPHNNQEELRIQDHCGDRDTPDSFVP 4003
P + P P + L + P + S +PP E R+ D+P S P
Sbjct: 585 PEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPP---PEASRLSP--PPEDSPMSPPP 639
Query: 4004 SSSPESVVGVEVSRYPDLSLVKEEPPEPVPSPIIPILPSTAGKSSESRRNDIKTEPGTLY 4063
SP S EVSR L +V P P SP+ P P + S + + P
Sbjct: 640 EESPMS-PPPEVSRLSPLPVVSRLSPPPEESPLSP-PPEESPTSPPPEASRLSPPPEDSP 697
Query: 4064 FASPFGPSPNGP 4075
+ P SP P
Sbjct: 698 TSPPPEDSPASP 709
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 188 bits (478), Expect = 1e-46
Identities = 109/294 (37%), Positives = 160/294 (54%), Gaps = 19/294 (6%)
Query: 4629 SPKGVWDKILEPVACVRKKSEMLQLFPAYLKGEDLFGLTVSAVARIAESLPGVEACENYT 4688
S +G W ++E V R + + L + + G L G+ AV +AE LPG + C++Y
Sbjct: 2430 SLEGAWRTLIEKVQEARGHARLRHLSFSGMSGARLLGIHHDAVIFLAEQLPGAQRCQHYK 2489
Query: 4689 FRYGRNPLMELPLAVNPTGCARSEP---KMSAHVKRFVLRPH-------TLNSTSTSKSF 4738
FRY + + +NP G AR+E K + + F+ H T +
Sbjct: 2490 FRYHQQGEGQEEPPLNPHGAARAEVYLRKCTFDMFNFLASQHRVLPEGATCDEEEDEVQL 2549
Query: 4739 QSTVTG-ELNAPYSKQFVHSKSSQYRKMKTEWKSNVYLARSRIQGLGLYAARDIEKHTMV 4797
+ST L P + +F H K + K V + RS I G GL+ R+I+ MV
Sbjct: 2550 RSTRRATSLELPMAMRFRHLKKTS--------KEAVGVYRSAIHGRGLFCKRNIDAGEMV 2601
Query: 4798 IEYIGTIIRNEVANRKEKLYESQNRGVYMFRMDNDHVIDATLTGGPARYINHSCAPNCVA 4857
IEY G +IR+ + +++EK Y+ + G YMFRMD+ V+DAT+ G AR+INHSC PNC +
Sbjct: 2602 IEYSGIVIRSVLTDKREKFYDGKGIGCYMFRMDDFDVVDATMHGNAARFINHSCEPNCFS 2661
Query: 4858 EVVTFERGHKIIISSSRRIQKGEELCYDYKFDFEDDQHKIPCHCGAVNCRKWMN 4911
V+ E I+I + RRI +GEEL YDYKF ED +K+PC+CGA CR+++N
Sbjct: 2662 RVIHVEGQKHIVIFALRRILRGEELTYDYKFPIEDASNKLPCNCGAKRCRRFLN 2715
Score = 139 bits (349), Expect = 9e-32
Identities = 81/211 (38%), Positives = 107/211 (50%), Gaps = 7/211 (3%)
Query: 4397 KDYRKCCFCHEEGDGLTDGPARLLNLDLDLWVHLNCALWSTEVYETQAGALINVELALRR 4456
+D R+C C + GD + RLL + + W H+NCA+WS EV+E G+L NV A+ R
Sbjct: 1576 EDPRQCALCLKYGDADSKEAGRLLYIGQNEWTHVNCAIWSAEVFEENDGSLKNVHAAVAR 1635
Query: 4457 GLQMKCVFCHKTGATSGCHRFRCTNIYHFTCAIKAQCMFFKDKTMLCPMHKP--KGIHEQ 4514
G QM+C C K GAT GC C + +HF CA + C+F DK + C H G
Sbjct: 1636 GRQMRCELCLKPGATVGCCLSSCLSNFHFMCARASYCIFQDDKKVFCQKHTDLLDGKEIV 1695
Query: 4515 ELSYFAVFRRVYVQRDEVRQIASIVQRGERDH-TFRVGSLIFHTIGQLLPQQMQAFHSPK 4573
F V RRVYV + + + E D +GS+ ++G L
Sbjct: 1696 NPDGFDVLRRVYVDFEGINFKRKFLTGLEPDAINVLIGSIRIDSLGTL----SDLSDCEG 1751
Query: 4574 ALFPVGYEASRLYWSTRYANRRCRYLCSIEE 4604
LFP+GY+ SRLYWST A RRC Y C I E
Sbjct: 1752 RLFPIGYQCSRLYWSTVDARRRCWYRCRILE 1782
Score = 107 bits (267), Expect = 3e-22
Identities = 59/176 (33%), Positives = 82/176 (46%), Gaps = 16/176 (9%)
Query: 959 MCVVCGSFGQGAEGRLLACSQCGQCYHPYCVSIKITKVVLSKG-WRCLECTVCEACG-KA 1016
+C++C S G L+ C C +HP+C+ + W C C C CG K
Sbjct: 1203 VCLLCASKGLH---ELVFCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKG 1259
Query: 1017 TDPGRLLLCDDCDISYHTYCLDPPLQTVP---KGGWKCKWCVWCRHCGATSA-GLRCEWQ 1072
LL C+ C +YH CL P T + W C CV C+ CGAT EW
Sbjct: 1260 RGSKHLLECERCRHAYHPACLGPSYPTRATRKRRHWICSACVRCKSCGATPGKNWDVEWS 1319
Query: 1073 NNYTQCAPCASL----SSCPVCYRNYREEDL---ILQCRQCDRWMHAVCQNLNTEE 1121
+Y+ C C L + CP+C R Y + D ++QC QCD W+HA C+ L+ E+
Sbjct: 1320 GDYSLCPRCTQLYEKGNYCPICTRCYEDNDYESKMMQCAQCDHWVHAKCEGLSDED 1375
Score = 105 bits (261), Expect = 1e-21
Identities = 58/178 (32%), Positives = 80/178 (44%), Gaps = 20/178 (11%)
Query: 344 CAVCDSPGDLLDQFFCTTCGQHYHGMCLDIAVTPLKRAG--WQCPECKVCQNCKQSGEDS 401
C +C S G L + FC C +H CL+ A PL + W C CK C C + G S
Sbjct: 1204 CLLCASKG-LHELVFCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKGRGS 1262
Query: 402 K-MLVCDTCDKGYHTFCLQPVMKSVPTNG------WKCKNCRICIECGTRSSS----QWH 450
K +L C+ C YH CL P S PT W C C C CG +W
Sbjct: 1263 KHLLECERCRHAYHPACLGP---SYPTRATRKRRHWICSACVRCKSCGATPGKNWDVEWS 1319
Query: 451 HNCLICDNCYQ--QQDNLCPFCGKCYHP-ELQKDMLHCNMCKRWVHLECDKPTDHELD 505
+ +C C Q ++ N CP C +CY + + M+ C C WVH +C+ +D + +
Sbjct: 1320 GDYSLCPRCTQLYEKGNYCPICTRCYEDNDYESKMMQCAQCDHWVHAKCEGLSDEDYE 1377
Score = 73.2 bits (178), Expect = 6e-12
Identities = 119/501 (23%), Positives = 181/501 (36%), Gaps = 76/501 (15%)
Query: 1742 QRESEHEQEWKFRQQMRQKSKQQAKI---EATQKLEQVKNEQQQQQQQQFGSQHLLVQSG 1798
Q + +HE+ W+ Q R S Q + QKL+ + E+++++++ + G
Sbjct: 327 QGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKD--------KEG 378
Query: 1799 SDTPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAPPPPPA 1858
+ + + P +E PP TP + P PPP P
Sbjct: 379 EEKEERAVAEEMMPAAEK----------EEAKLPPPPLTPPA---------PSPPPPLPP 419
Query: 1859 PSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRN 1918
PS P PP P V P PSP P A+ PPPV + R
Sbjct: 420 PSTSP------PPPLCPPPPPPVSPPPL-----PSPPPPPAQEEQEESPPPVVPATCSRK 468
Query: 1919 SAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPV-MTDQ 1977
P PL+ P Q E A R P + T + P D+P +
Sbjct: 469 RGRP-----PLT----PSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTT 519
Query: 1978 FPKSLGLSRSPVVSEQTAKG-PIAAGTSDHFTKPSPRADVFQRQRIPDSYARPL-LTPAP 2035
F K++ PVVS ++++ D P+ +V R P + + P+ PAP
Sbjct: 520 FLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAP 579
Query: 2036 LDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYS 2095
+ S P P P P + + + + R + E P P P + + P +
Sbjct: 580 VPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPAT 639
Query: 2096 ---QPPLTPHPAVNESFAHPS--RAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQSSG 2150
+P L P S AH + P + P + +P +PP P DS ++
Sbjct: 640 SSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEP--EPP----PADDSPAEPEP 693
Query: 2151 TARSNTDPYSQPPGTPRPTT-----VDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAH 2205
A T+ S P P TT V P+ + P TQ L Q P A
Sbjct: 694 RAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQAL 753
Query: 2206 PPGTPRPGISVPYSQPPATPR 2226
PP P+P + QPP +P+
Sbjct: 754 PP--PQPQL-----QPPPSPQ 767
Score = 61.6 bits (148), Expect = 2e-08
Identities = 32/84 (38%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Query: 250 WAHHRCVEWSLGVCQMEEPLLVNVDKAVVSGSTERCAFCKHLGATIKCCEEKCTQMYHYP 309
W H C WS V + + L NV AV G RC C GAT+ CC C +H+
Sbjct: 1606 WTHVNCAIWSAEVFEENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSCLSNFHFM 1665
Query: 310 CA-AGAGTFQDFSHIFLLCPEHID 332
CA A FQD +F C +H D
Sbjct: 1666 CARASYCIFQDDKKVF--CQKHTD 1687
Score = 52.0 bits (123), Expect = 1e-05
Identities = 124/580 (21%), Positives = 186/580 (32%), Gaps = 113/580 (19%)
Query: 2029 PLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHN 2088
PL P P P P +P PPP+ ++ S RP LTP
Sbjct: 427 PLCPPPPPPVSPPPLPSP-PPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAA 485
Query: 2089 QSNDPYSQPPLTPHPAV---------------NESFAHPSRAFSQPGTISRPT------- 2126
++ + PP TP P+ + +F R F P +R +
Sbjct: 486 RAGPEGTSPP-TPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPR 544
Query: 2127 ---SQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRP 2183
+DP P PV+ +S P PP P P P TP P
Sbjct: 545 RFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTP---------PSTPVP 595
Query: 2184 STQTDLFV--------TPVTNQRHSDPYAHPPG---TPRPGISVPYSQPPATPRPRISEG 2232
+ + T +T + P A PP +P P + +P P+ +
Sbjct: 596 LPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPS 655
Query: 2233 FTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSP 2292
+ VL P P L A P P P P D P P G ++ S
Sbjct: 656 EAHLKIYESVLTP---PPLGA-----PEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRF 707
Query: 2293 SAARDPYDQSPMTPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGV 2352
+ ++ ++P QT + QP + + P Q Q
Sbjct: 708 APVVTTPVKAEVSPHGAPALSNGPQTQAQLL-QPLQALQTQLLPQALPPPQPQLQPPPSP 766
Query: 2353 SQLP----------GPVPTSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKKIA- 2401
Q+P G +P SGV + + L +R K++ + QQQQ+K+A
Sbjct: 767 QQMPPLEKARIAGVGSLPLSGVEEKMFS----------LLKRAKVQLFKIDQQQQQKVAA 816
Query: 2402 -------GRQEKGSQDSPAVPHPGPLQHWQPENVNQAFTRPPPPYPGNIRSPVAPPLGPR 2454
G+ E+ + + GP++ + E+V RP P +P GPR
Sbjct: 817 SMPLSPGGQMEEVAGAVKQISDRGPVRS-EDESVEAKRERP--------SGPESPVQGPR 867
Query: 2455 Y-------AVFPKDQRGPYPPDVASMGMRPHGFRFGFPGGSHGTMPSQERFLVPPQQIQG 2507
AV R P DV + P R + T + E VP + +G
Sbjct: 868 IKHVCRHAAVALGQARAMVPEDVPRLSALPLRDRQDL--ATEDTSSASETESVPSRSRRG 925
Query: 2508 SGVSPQLRRSVSVDMPRPLNNSQMNNPVGLPQHFSPQSLP 2547
V+ P S+ G H +SLP
Sbjct: 926 -----------KVEAAGPGGESEPTGSGGTLAHTPRRSLP 954
Score = 47.8 bits (112), Expect = 3e-04
Identities = 36/159 (22%), Positives = 59/159 (37%), Gaps = 43/159 (27%)
Query: 390 VCQNCKQSGEDSKMLVCDTCDKGYHTFCLQPVMKSVPTNG--WKCKNCRICIECGTRSSS 447
VC C G +++ C C +H FCL+ + +P + W C+ C+ C CG +
Sbjct: 1203 VCLLCASKGLH-ELVFCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKGRG 1261
Query: 448 QWHHNCLICDNCYQQQDNLCPFCGKCYHPELQKDMLHCNMCKRWVHLECDKPTDHELDTQ 507
H +L C C+ H C P+ T+
Sbjct: 1262 SKH-------------------------------LLECERCRHAYHPACLGPSYPTRATR 1290
Query: 508 LKEEYI---CMYCKHLGAEMDRLQPGEEVEIAELTTDYN 543
+ +I C+ CK GA PG+ ++ E + DY+
Sbjct: 1291 KRRHWICSACVRCKSCGA-----TPGKNWDV-EWSGDYS 1323
Score = 39.7 bits (91), Expect = 0.075
Identities = 41/170 (24%), Positives = 64/170 (37%), Gaps = 23/170 (13%)
Query: 3220 KKAGREFPEEDAEQLKHVTEQQSMVQKQLEQIRKQQKEHAELIEDYRIKQQQQCAMAP-- 3277
KK ++ +E+ E+ + + + +K+ + ++ AE E+ ++ AP
Sbjct: 355 KKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEK-EEAKLPPPPLTPPAPSP 413
Query: 3278 --PTMMPSVQPQPPLIPGATPPTMSQPTFPMVP----QQLQHQQHTTVISGHTSPV--RM 3329
P PS P PPL P PP +S P P P Q+ Q + V+ S R
Sbjct: 414 PPPLPPPSTSPPPPLCP-PPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRP 472
Query: 3330 PSLPGWQPNSAPAHLPLNPPRIQPPIAQLPIKTCTPAPGTVSNANPQSGP 3379
P P + A P PP TP P T + P+ P
Sbjct: 473 PLTPSQRAEREAAR--AGPEGTSPP---------TPTPSTATGGPPEDSP 511
Score = 35.8 bits (81), Expect = 1.1
Identities = 25/71 (35%), Positives = 34/71 (47%), Gaps = 3/71 (4%)
Query: 3842 GGSET-KKQRSKRTQRTGEKAAPRSKKRKKDEEEKQAMYSSTDTFTHLKQQNNLSNPP-T 3899
GGS KKQ K EK K ++ +E+E++A+ K++ L PP T
Sbjct: 349 GGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAE-KEEAKLPPPPLT 407
Query: 3900 PPASLPPTPPP 3910
PPA PP P P
Sbjct: 408 PPAPSPPPPLP 418
Score = 35.4 bits (80), Expect = 1.4
Identities = 20/50 (40%), Positives = 25/50 (50%), Gaps = 5/50 (10%)
Query: 12 PQPPPPPPEEPGAPAPSPA--AADKRPRGRPRKDGASPFQRARKKPRSRG 59
P PPPPP +E +P P A R RGRP +P QRA ++ G
Sbjct: 442 PSPPPPPAQEEQEESPPPVVPATCSRKRGRP---PLTPSQRAEREAARAG 488
Score = 34.3 bits (77), Expect = 3.1
Identities = 14/28 (50%), Positives = 18/28 (64%), Gaps = 1/28 (3%)
Query: 10 EQPQPPPPPPEEPG-APAPSPAAADKRP 36
E P PPP PP P +P P+PA + +RP
Sbjct: 617 ELPPPPPAPPPPPAPSPPPAPATSSRRP 644
Score = 33.9 bits (76), Expect = 4.1
Identities = 20/66 (30%), Positives = 25/66 (37%)
Query: 14 PPPPPPEEPGAPAPSPAAADKRPRGRPRKDGASPFQRARKKPRSRGKTAVEDEDSMDGLE 73
PPPPP P P+P P A + P + R R +P E E + G E
Sbjct: 431 PPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPE 490
Query: 74 TTETET 79
T T
Sbjct: 491 GTSPPT 496
Score = 32.7 bits (73), Expect = 9.1
Identities = 36/114 (31%), Positives = 45/114 (39%), Gaps = 23/114 (20%)
Query: 820 TPKIGMGKPAITKRKFSPGRP-----RSKQGAWSTHNTVSPPSWSPDISEGREIFKPRQL 874
TP+ G+P PGRP R +Q V+ P P + +
Sbjct: 215 TPRRSRGRP--------PGRPAGPCRRKQQAVVVAEAAVTIPKPEPP----PPVVPVKHQ 262
Query: 875 PGSAIWSIKVGRGSGFPGKRRPRGAGLSGRGGR-GRSKLKSGIGAVVLPGVSTA 927
GS W K G G PG PR G S RGGR GR + + G V+ VS A
Sbjct: 263 TGS--WKCKEGPG---PGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRA 311
Score = 32.7 bits (73), Expect = 9.1
Identities = 14/26 (53%), Positives = 14/26 (53%)
Query: 15 PPPPPEEPGAPAPSPAAADKRPRGRP 40
PPPPP P PAPSP A RP
Sbjct: 619 PPPPPAPPPPPAPSPPPAPATSSRRP 644
>gi|56550039 myeloid/lymphoid or mixed-lineage leukemia protein [Homo
sapiens]
Length = 3969
Score = 181 bits (458), Expect = 2e-44
Identities = 107/314 (34%), Positives = 160/314 (50%), Gaps = 6/314 (1%)
Query: 4601 SIEEKDGRPVFVIRIVEQGHEDLVLSDISPKGVWDKILEPVACVRKKSEMLQLFPAYLKG 4660
SI EK + V I + I + W + + V R + + QL A + G
Sbjct: 3659 SITEKKPKKGLVFEISSDDGFQICAESI--EDAWKSLTDKVQEARSNARLKQLSFAGVNG 3716
Query: 4661 EDLFGLTVSAVARIAESLPGVEACENYTFRYGRNPLMELPLAVNPTGCARSEP---KMSA 4717
+ G+ AV + E L G + C NY FR+ + P +NP G AR+E K +
Sbjct: 3717 LRMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEP-PLNPHGSARAEVHLRKSAF 3775
Query: 4718 HVKRFVLRPHTLNSTSTSKSFQSTVTGELNAPYSKQFVHSKSSQYRKMKTEWKSNVYLAR 4777
+ F+ H + +A + ++R +K K V + R
Sbjct: 3776 DMFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFRHLKKTSKEAVGVYR 3835
Query: 4778 SRIQGLGLYAARDIEKHTMVIEYIGTIIRNEVANRKEKLYESQNRGVYMFRMDNDHVIDA 4837
S I G GL+ R+I+ MVIEY G +IR+ +++EK Y+S+ G YMFR+D+ V+DA
Sbjct: 3836 SPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYYDSKGIGCYMFRIDDSEVVDA 3895
Query: 4838 TLTGGPARYINHSCAPNCVAEVVTFERGHKIIISSSRRIQKGEELCYDYKFDFEDDQHKI 4897
T+ G AR+INHSC PNC + V+ + I+I + R+I +GEEL YDYKF ED +K+
Sbjct: 3896 TMHGNAARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKFPIEDASNKL 3955
Query: 4898 PCHCGAVNCRKWMN 4911
PC+CGA CRK++N
Sbjct: 3956 PCNCGAKKCRKFLN 3969
Score = 152 bits (385), Expect = 6e-36
Identities = 85/218 (38%), Positives = 116/218 (53%), Gaps = 8/218 (3%)
Query: 4390 LKPDPVPKDYRKCCFCHEEGDGLTDGPARLLNLDLDLWVHLNCALWSTEVYETQAGALIN 4449
L P P +D R+C C GD + RLL + + W H+NCALWS EV+E G+L N
Sbjct: 1861 LNPPPGIEDNRQCALCLTYGDDSANDAGRLLYIGQNEWTHVNCALWSAEVFEDDDGSLKN 1920
Query: 4450 VELALRRGLQMKCVFCHKTGATSGCHRFRCTNIYHFTCAIKAQCMFFKDKTMLCPMHKP- 4508
V +A+ RG Q++C FC K GAT GC CT+ YHF C+ C+F DK + C H+
Sbjct: 1921 VHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFMCSRAKNCVFLDDKKVYCQRHRDL 1980
Query: 4509 -KGIHEQELSYFAVFRRVYVQRDEVRQIASIVQRGERDHT-FRVGSLIFHTIGQLLPQQM 4566
KG E + F VFRRV+V + + + E ++ +GS+ +G L
Sbjct: 1981 IKGEVVPE-NGFEVFRRVFVDFEGISLRRKFLNGLEPENIHMMIGSMTIDCLGIL----N 2035
Query: 4567 QAFHSPKALFPVGYEASRLYWSTRYANRRCRYLCSIEE 4604
LFP+GY+ SR+YWST A +RC Y C I E
Sbjct: 2036 DLSDCEDKLFPIGYQCSRVYWSTTDARKRCVYTCKIVE 2073
Score = 117 bits (293), Expect = 3e-25
Identities = 111/441 (25%), Positives = 177/441 (40%), Gaps = 55/441 (12%)
Query: 723 EKEQKENSELSTGLMDSEMTPTIEGCVKDVSYQGGKSIKLSSETESSFSSSADISKADVS 782
EK+ + S + ++DS PT S + + K SS + S+
Sbjct: 1224 EKKDSKESSVVKNVVDSSQKPT-------PSAREDPAPKKSSSEPPPRKPVEEKSEEGNV 1276
Query: 783 SSPTPSSDLPSHDMLHNYPSALSSSAGNIMPTTYISVTPKIGMGKPAITKRKFSPGRPRS 842
S+P P S + P++ SS P I P G P K +P P+
Sbjct: 1277 SAPGPESKQATT------PASRKSSKQVSQPALVIPPQPPT-TGPPRKEVPKTTPSEPKK 1329
Query: 843 KQGAWSTHNTVSPPSWSPDISEGREIFKPRQLPGSAIWSIKVGRGSGFPGKRRPRGAG-- 900
KQ PP P+ S+ +++ +P K P + AG
Sbjct: 1330 KQPP--------PPESGPEQSKQKKVAPRPSIPVKQ----KPKEKEKPPPVNKQENAGTL 1377
Query: 901 --LSGRGGRGRSKLKSGIGAVVLPGVSTADISSNKDDEENSMHNTVVLFSSSDKFTLNQD 958
LS SK K + GV + +D E ++ L + +
Sbjct: 1378 NILSTLSNGNSSKQK-----IPADGVHRIRVDFKEDCEAENVWEMGGLGILTSVPITPRV 1432
Query: 959 MCVVCGSFGQGAEGRLLACSQCGQCYHPYCVSIKITKVVLS-KGWRCLECTVCEACGKAT 1017
+C +C S G + C C + +H +C+ + + W C C C CG+
Sbjct: 1433 VCFLCASSGHV---EFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQH 1489
Query: 1018 DPGRLLL-CDDCDISYHTYCLDPPLQTVP---KGGWKCKWCVWCRHCGATSAGLR--CEW 1071
+ LL C+ C SYH CL P T P K W C CV C+ CG+T+ G +W
Sbjct: 1490 QATKQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQW 1549
Query: 1072 QNNYTQCAPCASLSS----CPVCYRNYREEDL---ILQCRQCDRWMHAVCQNLNTE--EE 1122
++++ C CA L + CP+C + Y ++D ++QC +CDRW+H+ C+NL+ E E
Sbjct: 1550 SHDFSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEMYEI 1609
Query: 1123 VENVAD-IGFDCSMCRPYMPA 1142
+ N+ + + + C C PA
Sbjct: 1610 LSNLPESVAYTCVNCTERHPA 1630
Score = 113 bits (283), Expect = 4e-24
Identities = 65/211 (30%), Positives = 101/211 (47%), Gaps = 19/211 (9%)
Query: 344 CAVCDSPGDLLDQFFCTTCGQHYHGMCLDIAVTPLKRA--GWQCPECKVCQNCKQSGEDS 401
C +C S G + + +C C + +H CL+ PL+ W C CK C C + + +
Sbjct: 1434 CFLCASSGHV-EFVYCQVCCEPFHKFCLEENERPLEDQLENWCCRRCKFCHVCGRQHQAT 1492
Query: 402 KMLV-CDTCDKGYHTFCLQPVMKSVPTNG---WKCKNCRICIECGTRS-----SSQWHHN 452
K L+ C+ C YH CL P + PT W C C C CG+ + +QW H+
Sbjct: 1493 KQLLECNKCRNSYHPECLGPNYPTKPTKKKKVWICTKCVRCKSCGSTTPGKGWDAQWSHD 1552
Query: 453 CLICDNCYQ--QQDNLCPFCGKCY-HPELQKDMLHCNMCKRWVHLECDKPTD--HELDTQ 507
+C +C + + N CP C KCY + + M+ C C RWVH +C+ +D +E+ +
Sbjct: 1553 FSLCHDCAKLFAKGNFCPLCDKCYDDDDYESKMMQCGKCDRWVHSKCENLSDEMYEILSN 1612
Query: 508 LKEE--YICMYCKHLGAEMDRLQPGEEVEIA 536
L E Y C+ C RL +E++I+
Sbjct: 1613 LPESVAYTCVNCTERHPAEWRLALEKELQIS 1643
Score = 63.9 bits (154), Expect = 4e-09
Identities = 31/84 (36%), Positives = 41/84 (48%), Gaps = 3/84 (3%)
Query: 250 WAHHRCVEWSLGVCQMEEPLLVNVDKAVVSGSTERCAFCKHLGATIKCCEEKCTQMYHYP 309
W H C WS V + ++ L NV AV+ G RC FC+ GAT+ CC CT YH+
Sbjct: 1898 WTHVNCALWSAEVFEDDDGSLKNVHMAVIRGKQLRCEFCQKPGATVGCCLTSCTSNYHFM 1957
Query: 310 CAAGAG-TFQDFSHIFLLCPEHID 332
C+ F D ++ C H D
Sbjct: 1958 CSRAKNCVFLDDKKVY--CQRHRD 1979
Score = 42.4 bits (98), Expect = 0.012
Identities = 107/469 (22%), Positives = 164/469 (34%), Gaps = 71/469 (15%)
Query: 1948 PVRDLCSSSTTNNDPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHF 2007
PV SSS + + + P + P + S+ +RSP V Q A SD
Sbjct: 2906 PVDSSVSSSISAEEQFELPLELPSDL-------SVLTTRSPTVPSQNPSR--LAVISDSG 2956
Query: 2008 TKPSPRADVFQRQRIPDSYARPLLTPAPLDSGPGPFKTP-------MQPPPSSQDPYGSV 2060
K R + ++ + S + P L +D P TP M S P GSV
Sbjct: 2957 EK---RVTITEKS-VASSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSV 3012
Query: 2061 SQA-------SRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPS 2113
Q +R S + P PI N + ++ P + AV + H
Sbjct: 3013 EQGHGNNQDLTRNSSTPGLQVPVSPTVPIQNQKYVPNSTDSPGPSQISNAAVQTTPPHLK 3072
Query: 2114 RAFSQPGTISRPTSQDPY---SQPPGTPRPV--VDSYSQSSGTARSNTDPYSQPPGTPRP 2168
A + +++ Q Y + P G + + S S + +NT G
Sbjct: 3073 PATEKLIVVNQ-NMQPLYVLQTLPNGVTQKIQLTSSVSSTPSVMETNTSVLGPMGGGLTL 3131
Query: 2169 TT-VDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYS------QP 2221
TT ++P Q+ PS L HS P A P P IS P S QP
Sbjct: 3132 TTGLNPSLPTSQSLFPSASKGLLPMSHHQHLHSFPAATQSSFP-PNISNPPSGLLIGVQP 3190
Query: 2222 PATPRPRISEGFTRSSMTRPVLMPNQD------PFLQAAQNR--GPALPGPLVRPPDTCS 2273
P P+ +SE R+ ++ V P+ LQ +N+ P+ + P D S
Sbjct: 3191 PPDPQLLVSESSQRTDLSTTVATPSSGLKKRPISRLQTRKNKKLAPSSTPSNIAPSDVVS 3250
Query: 2274 Q------TPR--PPGPGLSDTFSRVSPSAARDP------------YDQSPMTPRSQSDSF 2313
TP P P L D S + S P ++ +P+ P+S +
Sbjct: 3251 NMTLINFTPSQLPNHPSLLDLGSLNTSSHRTVPNIIKRSKSSIMYFEPAPLLPQSVGGTA 3310
Query: 2314 GTSQTAHDVADQPRPGSEGSF--CASSNSPMHSQGQQFSGVSQLPGPVP 2360
T+ ++ + GS ASS+S ++ Q + VP
Sbjct: 3311 ATAAGTSTISQDTSHLTSGSVSGLASSSSVLNVVSMQTTTTPTSSASVP 3359
Score = 40.8 bits (94), Expect = 0.033
Identities = 108/506 (21%), Positives = 169/506 (33%), Gaps = 97/506 (19%)
Query: 3582 YPGSTQSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTKAPSTPHSDITAPPTPGISETT 3641
YP S ++ + + KK T +KK T S D TA T + +
Sbjct: 906 YPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKG 965
Query: 3642 STPAVSTPSELPQQADQESVEPVGPSTPNMAAGQLCTELENKLPNSDFSQATPNQQTYAN 3701
T +L GP+ P++ E E L S S +T T +
Sbjct: 966 RGNLEKTNLDL------------GPTAPSL-------EKEKTLCLSTPSSSTVKHSTSSI 1006
Query: 3702 ----SEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVEGNAVACPVSSAQ 3757
++ DKL M K L+KA+ + C ++ L++ + K +G +S +
Sbjct: 1007 GSMLAQADKLPMTD--KRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVR 1064
Query: 3758 SP---------PHSAGAPAAKGDSGNELLKHLL--KNKKSSSLLNQKPEGSICSEDDC-- 3804
P + G A L L + +K S + + SI +D
Sbjct: 1065 GPRIKHVCRRAAVALGRKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEP 1124
Query: 3805 ----------TKDNKLVEKQNPAEGL------QTLGAQMQGGFG-CGNQLPKTD-GGSET 3846
NK ++ +G Q G Q+ G C N L K GG
Sbjct: 1125 LAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGRNI 1184
Query: 3847 KKQ-------------RSKRTQRTGEKAAPRSKKRKKDEEEKQAMYSSTDTFTHLKQQNN 3893
KKQ SK + KA + +K+ K E+K + SS +K +
Sbjct: 1185 KKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSV-----VKNVVD 1239
Query: 3894 LSNPPTPPASLPPTPPPMACQKMANGFATTEELAGKAGVLV----SHEVTKTLGPKPFQL 3949
S PTP A P P + + EE + + V S + T K +
Sbjct: 1240 SSQKPTPSAREDPAPKKSSSEPPPR--KPVEEKSEEGNVSAPGPESKQATTPASRKSSKQ 1297
Query: 3950 PFRPQDDLLARALAQGPKTVDVPASLPTPPHNNQEELRIQDHCGDRDTPDSFVPSSSPES 4009
+P + + GP +VP + P+ P Q P S PE
Sbjct: 1298 VSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPP----------------PPESGPEQ 1341
Query: 4010 VVGVEVSRYPDLSLVKEEPPEPVPSP 4035
+V+ P + VK++P E P
Sbjct: 1342 SKQKKVAPRPSIP-VKQKPKEKEKPP 1366
Score = 38.1 bits (87), Expect = 0.22
Identities = 109/475 (22%), Positives = 172/475 (36%), Gaps = 76/475 (16%)
Query: 1648 MATVAPVLYTNINFPNLKEEFPDWTTRVKQIAKLWRKASSQERAPYVQKARDNRAALRIN 1707
M V+ + I P E D+ +K IA+L +S+ AP + + AA + +
Sbjct: 411 MPVVSAISSRIIKTPRRFIEDEDYDPPIK-IARLESTPNSRFSAPSCGSSEKSSAASQ-H 468
Query: 1708 KVQMSNDSMK------------RQQQQDSIDPSSRIDSELFKDPLKQRESEHEQEWKFRQ 1755
QMS+DS + + ++ + P R D+ PL +S + R
Sbjct: 469 SSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRS 528
Query: 1756 QMRQKSKQQAKIEATQKLEQVKNEQQQQQQQQFGSQHLLVQSGSDTPSSGIQS------- 1808
+ S++ T+KL +++ QQQ LL P+S I
Sbjct: 529 RRYSVSERSFGSRTTKKLSTLQSAPQQQTSSS-PPPPLLTPPPPLQPASSISDHTPWLMP 587
Query: 1809 ---PLTPQPGNGNMSPAQSFHKELF---------TKQPPSTPTSTSS-----DDVFVKP- 1850
PL + +P Q K + K S P SS + + KP
Sbjct: 588 PTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQYFSSAKYAKEGLIRKPI 647
Query: 1851 --QAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPR-P 1907
PPP P + S + T+ S ++FSP S +R M + ++ PR
Sbjct: 648 FDNFRPPPLTPEDVGFASGFSASGTA--ASARLFSPLHSGTR--FDMHKRSPLLRAPRFT 703
Query: 1908 PPVGHSF--------SRRNSAAPVENCTPLSSVSRPLQMNETTANRP-SPVRDLCSSSTT 1958
P HS S R SA + + +S+ R ++ + P SP + + S
Sbjct: 704 PSEAHSRIFESVTLPSNRTSAG--TSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGR 761
Query: 1959 NNDPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQ 2018
+ P P V + SL +S SP+ + +A P S T+ A+ Q
Sbjct: 762 LSSSELSPLTPPSSVSS-----SLSISVSPLAT--SALNPTFTFPSHSLTQSGESAEKNQ 814
Query: 2019 RQRIPDSYARPLLTPAPLDSGPGPFKTPMQP--PPSSQDPYG-SVSQASRRLSVD 2070
R R T AP + TP+ P P SQ G + +A LS D
Sbjct: 815 RPR--------KQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKD 861
Score = 38.1 bits (87), Expect = 0.22
Identities = 53/246 (21%), Positives = 92/246 (37%), Gaps = 16/246 (6%)
Query: 1675 VKQIAKLWRKASSQERAPYVQKARDNRAALRINKVQMSNDSMKRQQQQDSIDPSSRIDSE 1734
+K I + R + QE P V+K R +R + Q+ D D R
Sbjct: 1129 IKPIKPVTRNKAPQE--PPVKKGRRSRRCGQCPGCQVPEDCGVCTNCLDKPKFGGR---N 1183
Query: 1735 LFKDPLKQRESEHEQEWKFRQQMRQKSKQQAKIEATQKLEQVKNEQQQQQQQQF-GSQHL 1793
+ K K R+ ++ Q + +++++K K E K + K+ ++ + S
Sbjct: 1184 IKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQK 1243
Query: 1794 LVQSGSDTPSSGIQS-------PLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDV 1846
S + P+ S P+ + GN+S K+ T + S +
Sbjct: 1244 PTPSAREDPAPKKSSSEPPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPAL 1303
Query: 1847 FVKPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSR-PPSPMDPY-AKMVGT 1904
+ PQ P P +P + + S+ + QPP P+ S + P P P K
Sbjct: 1304 VIPPQPPTTGPPRKEVP-KTTPSEPKKKQPPPPESGPEQSKQKKVAPRPSIPVKQKPKEK 1362
Query: 1905 PRPPPV 1910
+PPPV
Sbjct: 1363 EKPPPV 1368
Score = 38.1 bits (87), Expect = 0.22
Identities = 59/248 (23%), Positives = 97/248 (39%), Gaps = 51/248 (20%)
Query: 2851 TPCSQASAHSDLND-----GEKTSLHPCDPDLFEKRTNRETAGPSANVIQASTQLPAQDV 2905
+P +A H L KT +H DL SA+ Q S D
Sbjct: 3441 SPSGEADEHYQLQHVNQLLASKTGIHSSQRDL-----------DSASGPQVSNFTQTVDA 3489
Query: 2906 INSCGITGSTPVLSSLLANEKSDNSDIRPSGSPPPPTL---PASPSNHVSSLPPFIAPPG 2962
NS G+ + + S++ A+ S P GSP P+ ASPS + P P
Sbjct: 3490 PNSMGLEQNKALSSAVQASPTS------PGGSPSSPSSGQRSASPSVPGPTKPK---PKT 3540
Query: 2963 RVLDNAMNSNVTVVSRVNHVFSQGVQVNPGLIPGQSTVNHSLGTGKPA-------TQTGP 3015
+ ++ +V+H+ + + + IP Q T + + GTG P T +
Sbjct: 3541 KRFQLPLDKGNGKKHKVSHLRTSSSEAH---IPDQETTSLTSGTGTPGAEAEQQDTASVE 3597
Query: 3016 QTSQSGTSSMSGPQQLMIPQTLAQQN------RERPLLLEEQ------PLLLQDLLDQER 3063
Q+SQ +G Q ++P+ QN P +EE+ PL+L +Q+R
Sbjct: 3598 QSSQKECGQPAG-QVAVLPEVQVTQNPANEQESAEPKTVEEEESNFSSPLMLWLQQEQKR 3656
Query: 3064 QEQQQQRQ 3071
+E +++
Sbjct: 3657 KESITEKK 3664
Score = 35.4 bits (80), Expect = 1.4
Identities = 50/210 (23%), Positives = 75/210 (35%), Gaps = 29/210 (13%)
Query: 3527 PNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAAPPVANSSLPCGQDSTITHGHSYPGST 3586
P S+ Q + +Q+ S A P +P + SS GQ S S PG T
Sbjct: 3478 PQVSNFTQTVDAPNSMGLEQNKALSSAVQASPTSPGGSPSSPSSGQRSA---SPSVPGPT 3534
Query: 3587 QSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTKAPSTPHSDITAPPTPGISETTS-TPA 3645
+ + +P +KG K+ + + P ETTS T
Sbjct: 3535 KPKPKTKRFQLPLDKGNGKKHKVSHLRTSSSEAHIPD--------------QETTSLTSG 3580
Query: 3646 VSTPSELPQQADQESVEPVGPSTPNMAAGQLCTELENKLPNSDFSQATPNQQTYANS--- 3702
TP +Q D SVE AGQ+ LP +Q N+Q A
Sbjct: 3581 TGTPGAEAEQQDTASVEQSSQKECGQPAGQVAV-----LPEVQVTQNPANEQESAEPKTV 3635
Query: 3703 EVDKLSMETPAK---TEEIKLEKAETESCP 3729
E ++ + +P +E K +++ TE P
Sbjct: 3636 EEEESNFSSPLMLWLQQEQKRKESITEKKP 3665
Score = 33.5 bits (75), Expect = 5.3
Identities = 144/617 (23%), Positives = 220/617 (35%), Gaps = 91/617 (14%)
Query: 2473 MGMRPHGFRFGFPGGSHG-TMPSQERFLVPPQQIQGSGVSPQLRRSVSVDMP-RPL---N 2527
MG RP G G +MP + PP Q++GS Q R +V + PL N
Sbjct: 2474 MGQRPCNNVSSDKIGDKGLSMPGVPK--APPMQVEGSAKELQAPRKRTVKVTLTPLKMEN 2531
Query: 2528 NSQMNNPVGLPQHFSPQSLPVQQHNILGQAYIELRHRAPDGRQRLPFSAPPGSVVEASSN 2587
SQ N + + SP S P+Q + I DG P +P + + S +
Sbjct: 2532 ESQSKNAL---KESSPAS-PLQIESTSPTEPISASENPGDGPVAQP--SPNNTSCQDSQS 2585
Query: 2588 LRHGNF------IPRPDFPGPRHTDPM-----RRPPQGLPNQLPVHPDLEQVPPSQQEQG 2636
+ N + PD P P+ RR + N L V S E+
Sbjct: 2586 NNYQNLPVQDRNLMLPDGPKPQEDGSFKRRYPRRSARARSNMFFGLTPLYGVR-SYGEED 2644
Query: 2637 HSVHSSSMVMRTLNHPLGGEFSEAP-LSTSVPSETTSDNLQITTQPSDGLEEKLDSDDPS 2695
+SSS + G+ A LSTS + N T S G EE+L S +
Sbjct: 2645 IPFYSSSTGKKRGKRSAEGQVDGADDLSTSDEDDLYYYNFTRTVISSGG-EERLASHN-L 2702
Query: 2696 VKELDVKDLEGVEVKD-LDDEDLENLNLDTEDGKVVELDTLDNLETNDPNLDDLLRSGEF 2754
+E + DL + D +DD + ++ K ++ + E NL
Sbjct: 2703 FREEEQCDLPKISQLDGVDDGTESDTSVTATTRKSSQIPKRNGKENGTENLK-------- 2754
Query: 2755 DIIAYTDPELDMGDKKSMFNEELDLPIDDKLDNQCVSVEPKKKE-QENKTLVLSDKHSPQ 2813
D D G+K+ + + + K+DN C SV K + Q++ LS S +
Sbjct: 2755 -----IDRPEDAGEKEHVTKSSVGHKNEPKMDN-CHSVSRVKTQGQDSLEAQLSSLESSR 2808
Query: 2814 KKSTVTNEVKTEVLSPNSKVESKCETEKNDENKDNV-----------DTPCSQASAHSD- 2861
+ T T K + + N+++ N ++ N+ +TP QA S
Sbjct: 2809 RVHTSTPSDKNLLDTYNTELLKSDSDNNNSDDCGNILPSDIMDFVLKNTPSMQALGESPE 2868
Query: 2862 ------LNDGEKTSLHPCDPDLFEKRTNRETAGPSANVIQASTQLPAQDVINSCGITGST 2915
LN GE L +NRE V S QLP + ++S
Sbjct: 2869 SSSSELLNLGEGLGLD----------SNREKDMGLFEVF--SQQLPTTEPVDS------- 2909
Query: 2916 PVLSSLLANEKSDNSDIRPSG-SPPPPTLPASPSNHVSSLPPFIAPPGRVLDNAMNSNVT 2974
V SS+ A E+ + PS S P PS + S L I+ G +V
Sbjct: 2910 SVSSSISAEEQFELPLELPSDLSVLTTRSPTVPSQNPSRL-AVISDSGEKRVTITEKSVA 2968
Query: 2975 VVSRVNHVFSQGVQVNP-------GLIPGQSTVNHSLGTGKPATQTGPQTSQSGTSSMSG 3027
+ S GV P I G +H + + G +Q T + S
Sbjct: 2969 SSESDPALLSPGVDPTPEGHMTPDHFIQGHMDADHISSPPCGSVEQGHGNNQDLTRNSST 3028
Query: 3028 P-QQLMIPQTLAQQNRE 3043
P Q+ + T+ QN++
Sbjct: 3029 PGLQVPVSPTVPIQNQK 3045
Score = 32.7 bits (73), Expect = 9.1
Identities = 32/154 (20%), Positives = 58/154 (37%), Gaps = 9/154 (5%)
Query: 2126 TSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPST 2185
TS+ S+ + VVDS + + +AR + P P V+ S++ P
Sbjct: 1222 TSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSEPPPRKPVEEKSEEGNVSAPGP 1281
Query: 2186 QTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFTRSSMTRPVLMP 2245
++ TP + + +P + +P QPP T PR T S + P
Sbjct: 1282 ESKQATTPASRKSSKQ-------VSQPALVIP-PQPPTTGPPRKEVPKTTPSEPKKKQPP 1333
Query: 2246 NQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPP 2279
+ + ++ + A P P + + +PP
Sbjct: 1334 PPESGPEQSKQKKVA-PRPSIPVKQKPKEKEKPP 1366
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 137 bits (344), Expect = 3e-31
Identities = 80/211 (37%), Positives = 111/211 (52%), Gaps = 10/211 (4%)
Query: 4703 VNPTGCARSEPKMSAHVKRFVLRPH-TLNSTSTSKSFQSTVTGELNAPYSKQFVHSKSSQ 4761
+N + + EP +PH + + S +S Q + + +
Sbjct: 1721 LNSSRASTDEPPADTQGMSIPAQPHASTRAGSERRSEQRRLLSSFTGSCDSDLLKFNQLK 1780
Query: 4762 YRKMKTEWKSNVYLARSRIQGLGLYAARDIEKHTMVIEYIGTIIRNEVANRKEKLYESQN 4821
+RK K ++ +S I GL+A I MVIEY+G IR +A+ +EK YE +
Sbjct: 1781 FRKKKLKF------CKSHIHDWGLFAMEPIAADEMVIEYVGQNIRQVIADMREKRYEDEG 1834
Query: 4822 RGV-YMFRMDNDHVIDATLTGGPARYINHSCAPNCVAEVVTFERGHKIIISSSRRIQKGE 4880
G YMFR+D+D +IDAT G AR+INHSC PNC A+V+T E KI+I S + I E
Sbjct: 1835 IGSSYMFRVDHDTIIDATKCGNFARFINHSCNPNCYAKVITVESQKKIVIYSKQHINVNE 1894
Query: 4881 ELCYDYKFDFEDDQHKIPCHCGAVNCRKWMN 4911
E+ YDYKF ED KIPC CG+ NCR +N
Sbjct: 1895 EITYDYKFPIED--VKIPCLCGSENCRGTLN 1923
Score = 53.5 bits (127), Expect = 5e-06
Identities = 124/580 (21%), Positives = 184/580 (31%), Gaps = 99/580 (17%)
Query: 1859 PSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRN 1918
P + QDS + A T PP+ +PG ++ P P A P P +F R+
Sbjct: 367 PFKAQPQDSATFAHTP-PPAQATPAPGFKSAFSPY-QTPVAHFPPPPEEPTATAAFGARD 424
Query: 1919 SAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTDQF 1978
S + A P P + + P PPDT + +
Sbjct: 425 SG----------------EFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGR- 467
Query: 1979 PKSLGLSRSPVVSE--QTAKGPIAAGTSDHFTKPSPRADVFQRQRI-------PDSYARP 2029
+ G S P S T + A H + S + + QR PDS
Sbjct: 468 -PTFGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTEL 526
Query: 2030 LLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALT------PRPID 2083
+ +P+ S S P+G+ SQ R P RP+ T P P+
Sbjct: 527 QMEGSPISSSSSQL--------SPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLP 578
Query: 2084 NFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVD 2143
+ ++ D P P P + P+ SQ ++ D + P + + +D
Sbjct: 579 DSDEDEELDLGLGPRPPPEPGPPD----PAGLLSQTAEVALDLVGD---RTPTSEK--MD 629
Query: 2144 SYSQSSGTARS-NTDPYSQPPGT----PRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQR 2198
QSSG + D P T P+P V P + PS P
Sbjct: 630 EGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAA--VAAPSVLAPTLPLPPPPGF 687
Query: 2199 HSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRG 2258
P PP P+PG +P PP P P P P +
Sbjct: 688 PPLPPPPPPPPPQPGFPMPPPLPPPPPPP-----------------PPAHPAVTVPPPPL 730
Query: 2259 PALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQSDSFGTSQT 2318
PA PG V PP P P PGL + PM+ + Q+ T
Sbjct: 731 PAPPG--VPPPPILPPLP-PFPPGLFPVMQVDMSHVLGGQWGGMPMSFQMQTQVLSRLMT 787
Query: 2319 AHDVADQP------------------RPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVP 2360
P P G F S++ P +GQ + + + VP
Sbjct: 788 GQGACPYPPFMAAAAAAASAGLQFVNLPPYRGPFSLSNSGP--GRGQHWPPLPKFDPSVP 845
Query: 2361 TSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKKI 2400
G Q + A D L ++L+ I+ + +K +
Sbjct: 846 PPGYMPRQEDPHKATVDGVLLVVLKELKAIMKRDLNRKMV 885
Score = 53.1 bits (126), Expect = 7e-06
Identities = 107/452 (23%), Positives = 144/452 (31%), Gaps = 116/452 (25%)
Query: 1801 TPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSS---DDVFVKPQAPPPPP 1857
TP+ G +S +P +P F PP PT+T++ D +AP PPP
Sbjct: 388 TPAPGFKSAFSPY-----QTPVAHF------PPPPEEPTATAAFGARDSGEFRRAPAPPP 436
Query: 1858 APSRIPIQDSLSQAQTSQPPSPQVFSPGSSNS-----RP-----PSPMDP--YAKMVGTP 1905
P P L++ + PP P P +NS RP P P D + +P
Sbjct: 437 LPPAEP----LAKEKPGTPPGP---PPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSP 489
Query: 1906 RPPPVGH-SFSRRNSAAPVENCTPLSSVSRP-----LQMNETTANRPSPVRDLCSSSTTN 1959
P H S R E T L + P LQM + + S + TN
Sbjct: 490 AGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTN 549
Query: 1960 NDPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQR 2019
+ P + P P + P + G D P P +D +
Sbjct: 550 SQPGFRGPTPP------------------------SSRPSSTGLEDISPTPLPDSDEDEE 585
Query: 2020 QRIPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTP 2079
LD G GP P PP DP G +SQ + +++D T
Sbjct: 586 ----------------LDLGLGPRPPPEPGPP---DPAGLLSQTA-EVALDLVGDRTPTS 625
Query: 2080 RPIDNFSHNQ------SNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQ 2133
+D + S+D P+T P A ++ PT P
Sbjct: 626 EKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTL--PLPP 683
Query: 2134 PPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTP 2193
PPG P P PG P P + P P P P + V P
Sbjct: 684 PPGFP------------PLPPPPPPPPPQPGFPMPPPLPP----PPPPPPPAHPAVTVPP 727
Query: 2194 VTNQRHSDPYAHPPGTPRPGISVPYSQPPATP 2225
P PPG P P I P PP P
Sbjct: 728 -------PPLPAPPGVPPPPILPPL--PPFPP 750
Score = 50.1 bits (118), Expect = 6e-05
Identities = 104/429 (24%), Positives = 155/429 (36%), Gaps = 83/429 (19%)
Query: 1798 GSDTPSSGIQSPLTP---QPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAPP 1854
G + P+ + P P Q G +SP KE+ + PP +P D+ V+P+
Sbjct: 1215 GVEEPADSREPPEEPGLSQEGAMLLSPEPPA-KEVEAR-PPLSPERAPEHDLEVEPE--- 1269
Query: 1855 PPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSF 1914
PP +P+Q L + +PPSP + S P P +P A+ P P + S
Sbjct: 1270 -PPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAE-DHPPHTPGLCGSL 1327
Query: 1915 SRRNSAAPVENC----TPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTP 1970
++ S V PLS S L + SS P++ P +P
Sbjct: 1328 AKSQSTETVPATPGGEPPLSGGSSGLSL---------------SSPQVPGSPFSYPAPSP 1372
Query: 1971 RPVMTDQFPKSLG--LSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYAR 2028
+ + P++ G S +P SE + GP+ P P D +
Sbjct: 1373 -SLSSGGLPRTPGRDFSFTPTFSEPS--GPLLLPVC-----PLPTGR-------RDERSG 1417
Query: 2029 PLLTPAPLDSG-PGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSH 2087
PL +P L++G P P P+ P + +V +A R P P L P P+ +
Sbjct: 1418 PLASPVLLETGLPLPLPLPLPLPLA----LPAVLRAQARA---PTPLPPLLPAPLAS--- 1467
Query: 2088 NQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQP----PGTPRPVVD 2143
PP+ P P S G + RP + + PG P+ V
Sbjct: 1468 -------CPPPMKRKP--GRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQTPVF 1518
Query: 2144 SYSQSSGTA----RSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRH 2199
+ T R+ P PP P+P P P P T L + NQ
Sbjct: 1519 PSTHDPRTVTLDFRNAGIPAPPPPLPPQP-------PPPPPPPPVEPTKLPFKELDNQWP 1571
Query: 2200 SDPYAHPPG 2208
S+ A PPG
Sbjct: 1572 SE--AIPPG 1578
Score = 48.1 bits (113), Expect = 2e-04
Identities = 88/334 (26%), Positives = 116/334 (34%), Gaps = 74/334 (22%)
Query: 1971 RPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPL 2030
RP M D+ P +G+ P S + + P + P P A + ARP
Sbjct: 1203 RPSMLDEPPLPVGVEE-PADSREPPEEPGLSQEGAMLLSPEPPAKEVE--------ARPP 1253
Query: 2031 LTP--AP---LDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNF 2085
L+P AP L+ P P PM P Q P P RP PRP
Sbjct: 1254 LSPERAPEHDLEVEPEP---PMMLPLPLQPPL-------------PPPRP---PRPPSPP 1294
Query: 2086 SHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSY 2145
++ D S P + P P + HP G++++ S + PG P+
Sbjct: 1295 PEPETTDA-SHPSVPPEPLAED---HPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGG- 1349
Query: 2146 SQSSGTARSNTD----PYSQPP--------GTPRPTTVDPYSQQPQTPRPSTQTDLFVTP 2193
SSG + S+ P+S P G PR D +S P PS L V P
Sbjct: 1350 --SSGLSLSSPQVPGSPFSYPAPSPSLSSGGLPRTPGRD-FSFTPTFSEPSGPLLLPVCP 1406
Query: 2194 VTNQRH---SDPYAHP----PGTPRPGISVPYSQPPATPRPRISEGFTRSSMTRPVLMPN 2246
+ R S P A P G P P +P P P + R+ P L+P
Sbjct: 1407 LPTGRRDERSGPLASPVLLETGLPLP---LPLPLPLPLALPAVLRAQARAPTPLPPLLPA 1463
Query: 2247 QDPFLQAAQNRGPALP-----------GPLVRPP 2269
R P P GPLVRPP
Sbjct: 1464 PLASCPPPMKRKPGRPRRSPPSMLSLDGPLVRPP 1497
Score = 42.4 bits (98), Expect = 0.012
Identities = 131/606 (21%), Positives = 190/606 (31%), Gaps = 123/606 (20%)
Query: 2116 FSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYS 2175
FSQ S P S GTP + GT S YS + +PT +S
Sbjct: 252 FSQDTAYSSCRLDTPNSYGQGTP------LTPRLGTPFSQDSSYS----SRQPTPSYLFS 301
Query: 2176 QQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFTR 2235
Q P + + + T N+RH Y H + P T + F
Sbjct: 302 QDPAVTFKARRHESKFTDAYNRRHEHHYVH-------------NSPAVTAVAGATAAFRG 348
Query: 2236 SSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPD--TCSQTPRP----PGPGLSDTFSR 2289
SS PF G + P +P D T + TP P P PG FS
Sbjct: 349 SSDL---------PFGAVGGTGGSSGPPFKAQPQDSATFAHTPPPAQATPAPGFKSAFSP 399
Query: 2290 VSPSAARDPYDQSPMTPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSNSP-------- 2341
A P T + + + + A P P +E +P
Sbjct: 400 YQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDT 459
Query: 2342 --MHSQGQQFSGVSQLPGPVPTSGVTDTQNTVNMAQADTEKLRQRQKLR-EIILQQQQQK 2398
M G+ G S P P + G T+ + A EK R E++L++Q+ K
Sbjct: 460 NSMELGGRPTFGWS--PEPCDSPGTP----TLESSPAGPEKPHDSLDSRIEMLLKEQRTK 513
Query: 2399 KIAGRQ-----EKGSQDSPAVPHPGPLQHWQPENVNQ--AFTRPPPPY--PGNIR----S 2445
+ R+ E + SP L P N F P PP P + S
Sbjct: 514 LLFLREPDSDTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDIS 573
Query: 2446 PVAPPLGPR-----YAVFPKDQRGPYPPDVASMGMRPHGFRFGFPGGSHGTMPSQERFLV 2500
P P + P+ P PPD A + + G P+ E+
Sbjct: 574 PTPLPDSDEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDR---TPTSEKM-- 628
Query: 2501 PPQQIQGSGVSPQLRRS-------VSVDMPRPLNNSQMNNPVGLPQHFSPQSLPVQQHNI 2553
+ Q SG ++ S D P+P+ + V P +P +LP+
Sbjct: 629 -DEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAP-TLPLPP--- 683
Query: 2554 LGQAYIELRHRAPDGRQRLPFSAPPGSVVEASSNLRHGNFIPRPDFPGPRHTDPMRRPPQ 2613
P G LP PP P+P FP P P PP
Sbjct: 684 ------------PPGFPPLPPPPPPPP--------------PQPGFPMPPPLPPPPPPPP 717
Query: 2614 GL-------PNQLPVHPDLEQVPPSQQEQGHSVHSSSMVMRTLNHPLGGEFSEAPLSTSV 2666
P LP P + P ++ ++H LGG++ P+S +
Sbjct: 718 PAHPAVTVPPPPLPAPPGVPPPPILPPLPPFPPGLFPVMQVDMSHVLGGQWGGMPMSFQM 777
Query: 2667 PSETTS 2672
++ S
Sbjct: 778 QTQVLS 783
Score = 41.6 bits (96), Expect = 0.020
Identities = 122/503 (24%), Positives = 170/503 (33%), Gaps = 112/503 (22%)
Query: 2023 PDSYAR--PLL----TPAPLDSGPGPFKTPMQPPPS---SQDPYGSVSQASRRLS---VD 2070
P+SY + PL TP DS + QP PS SQDP +V+ +RR D
Sbjct: 266 PNSYGQGTPLTPRLGTPFSQDSS----YSSRQPTPSYLFSQDP--AVTFKARRHESKFTD 319
Query: 2071 PYER----------PALTPRPIDNFSHNQSND-PY---------SQPPLTPHPAVNESFA 2110
Y R PA+T + S+D P+ S PP P + +FA
Sbjct: 320 AYNRRHEHHYVHNSPAVTAVAGATAAFRGSSDLPFGAVGGTGGSSGPPFKAQPQDSATFA 379
Query: 2111 H---PSRAFSQPGTISR----PTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQPP 2163
H P++A PG S T + PP P ++ SG R P PP
Sbjct: 380 HTPPPAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPLPP 439
Query: 2164 GTPRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPA 2223
P + P P P T + T +P PGTP S P
Sbjct: 440 A--EPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEP-CDSPGTP-----TLESSPAG 491
Query: 2224 TPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGL 2283
+P S S +L + L +R PD+ ++ P +
Sbjct: 492 PEKPHDS----LDSRIEMLLKEQRTKLL-------------FLREPDSDTELQMEGSP-I 533
Query: 2284 SDTFSRVSPSAA----RDPYDQSPMTPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSN 2339
S + S++SP A P + P P S+ S G D++ P P S+
Sbjct: 534 SSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLE----DISPTPLPDSDED------ 583
Query: 2340 SPMHSQGQQFSGVSQLPGPVPTSGVTDTQNTVNM-AQADTEKLRQRQKLREIILQQQQQK 2398
+ + P P P G D ++ A+ + + R E + + QQ
Sbjct: 584 --------EELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQS- 634
Query: 2399 KIAGRQEKGSQDS-------------PAVPHPGPLQHWQPENVNQAFTRPPPPYPGNIRS 2445
+G + S D P V PG P + A T P PP PG
Sbjct: 635 --SGEDMEISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVL--APTLPLPPPPGFPPL 690
Query: 2446 PVAPPLGPRYAVFPKDQRGPYPP 2468
P PP P FP P PP
Sbjct: 691 PPPPPPPPPQPGFPMPPPLPPPP 713
Score = 38.9 bits (89), Expect = 0.13
Identities = 80/413 (19%), Positives = 149/413 (36%), Gaps = 39/413 (9%)
Query: 2647 RTLNHPLGGEFSEAPLSTSVPSETTSDNLQITTQPSDGLEEKLDSDDPSVKELDVKDLEG 2706
R L GGE E S S E+T + + + + ++ DSDD E D +D
Sbjct: 1025 RPLELDSGGEEDEKE-SLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDDEDTAL 1083
Query: 2707 VEVKDLDDEDLENLNLDTEDGKVVELDTLDNLETNDPNLDDLLRSGEFDIIAYTDPELDM 2766
E + D+ D+++ + V + T T+ + S EF+ + + P
Sbjct: 1084 SEASEKDEG-------DSDEEETVSIVTSKAEATSSSESSE---SSEFESSSESSPSSSE 1133
Query: 2767 GDKKSMFNEELDLPIDDKL--DNQCVSVEPKKKEQENKTLVLSDKHSPQKKSTVTNEVKT 2824
+++ + EE + ++++ + S P+ EQ+ + L+
Sbjct: 1134 DEEEVVAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALA-----------PGAPAV 1182
Query: 2825 EVLSPNSKVESKCETEKNDENKDNVDTPCSQASAHSDLNDGEKTSLHPCDPDLFEKRTNR 2884
+ L +V+ + E +E +D P + E P +P L ++
Sbjct: 1183 DSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREP----PEEPGLSQEGAML 1238
Query: 2885 ETAGPSANVIQASTQL-PAQDVINSCGITGSTPVLSSLLANEKSDNSDIRPSGSPPPPTL 2943
+ P A ++A L P + + + P++ L + P P PP+
Sbjct: 1239 LSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPL-----QPPLPPPRPPRPPSP 1293
Query: 2944 PASPSNHVSSLPPFIAPPGRVLDNAMNSNVTVVSRVNHVFSQGVQVNPGLIPGQSTVNHS 3003
P P +S P + P D+ ++ S ++ V PG P S +
Sbjct: 1294 PPEPETTDAS-HPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSG 1352
Query: 3004 LGTGKPATQTGPQTSQSGTSSMSGPQQLMIPQTLAQQNRERPLLLEEQ-PLLL 3055
L P P + + + S+S +P+T + P E PLLL
Sbjct: 1353 LSLSSPQVPGSPFSYPAPSPSLSSGG---LPRTPGRDFSFTPTFSEPSGPLLL 1402
Score = 37.4 bits (85), Expect = 0.37
Identities = 36/136 (26%), Positives = 47/136 (34%), Gaps = 25/136 (18%)
Query: 1778 NEQQQQQQQQFGSQHLLVQSGSDTPSSGIQS-----PLTPQPGNGNMSPAQSFHKELFTK 1832
+E+ + QQ G + S + PS+ I S P+ PG ++ L
Sbjct: 625 SEKMDEGQQSSGEDMEI--SDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLP 682
Query: 1833 QPPSTPTSTSSDDVFVKPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPP 1892
PP P P PPPPP P+ L PP P P + PP
Sbjct: 683 PPPGFPPL---------PPPPPPPPPQPGFPMPPPL----PPPPPPPPPAHPAVTVPPPP 729
Query: 1893 SPMDPYAKMVGTPRPP 1908
P P G P PP
Sbjct: 730 LPAPP-----GVPPPP 740
Score = 36.6 bits (83), Expect = 0.63
Identities = 34/130 (26%), Positives = 51/130 (39%), Gaps = 18/130 (13%)
Query: 3275 MAPPTMMPSVQPQPPLIPGATPPT-----MSQPTFPMVPQQLQHQQHTTVISG----HTS 3325
M P + P + P P P + PP S P+ P P H HT + G S
Sbjct: 1273 MLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQS 1332
Query: 3326 PVRMPSLPGWQP--NSAPAHLPLNPPRIQPPIAQLPIKTCTPAPGTVSNANPQSGPPPRV 3383
+P+ PG +P + + L L+ P++ P P+P S P++ P
Sbjct: 1333 TETVPATPGGEPPLSGGSSGLSLSSPQVPGS----PFSYPAPSPSLSSGGLPRT---PGR 1385
Query: 3384 EFDDNNPFSE 3393
+F FSE
Sbjct: 1386 DFSFTPTFSE 1395
Score = 35.0 bits (79), Expect = 1.8
Identities = 12/18 (66%), Positives = 13/18 (72%)
Query: 12 PQPPPPPPEEPGAPAPSP 29
P PPPPPP +PG P P P
Sbjct: 691 PPPPPPPPPQPGFPMPPP 708
Score = 34.3 bits (77), Expect = 3.1
Identities = 52/203 (25%), Positives = 75/203 (36%), Gaps = 39/203 (19%)
Query: 2165 TPRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPA- 2223
+P P + ++ P +P + + DL V P P P PRP +PP+
Sbjct: 1240 SPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRP------PRPPSP 1293
Query: 2224 TPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVR--PPDTCSQTP--RPP 2279
P P ++ + P + P +P + P L G L + +T TP PP
Sbjct: 1294 PPEPETTDA------SHPSVPP--EPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPP 1345
Query: 2280 GPGLSDTFSRVSPSAARDPYDQSPMTPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSN 2339
G S S SP P+ S P S G +T PG + SF + +
Sbjct: 1346 LSGGSSGLSLSSPQVPGSPF--SYPAPSPSLSSGGLPRT---------PGRDFSFTPTFS 1394
Query: 2340 SPMHSQGQQFSGVSQLP-GPVPT 2361
P SG LP P+PT
Sbjct: 1395 EP--------SGPLLLPVCPLPT 1409
Score = 32.7 bits (73), Expect = 9.1
Identities = 29/91 (31%), Positives = 37/91 (40%), Gaps = 14/91 (15%)
Query: 3274 AMAPPTMMPSVQPQPPL-----IPGATPPTMSQPTFPMVPQQLQHQQHTTVISGHTSPVR 3328
A+A P+++ P PP +P PP QP FPM P L + V
Sbjct: 668 AVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPGFPM-PPPLPPPPPPPPPAHPAVTVP 726
Query: 3329 MPSLPGWQPNSAPAHLPLNPPRIQPPIAQLP 3359
P LP AP +P PP I PP+ P
Sbjct: 727 PPPLP------APPGVP--PPPILPPLPPFP 749
>gi|55741677 SET domain containing 1A [Homo sapiens]
Length = 1707
Score = 129 bits (324), Expect = 7e-29
Identities = 69/143 (48%), Positives = 88/143 (61%), Gaps = 3/143 (2%)
Query: 4770 KSNVYLARSRIQGLGLYAARDIEKHTMVIEYIGTIIRNEVANRKEKLYESQNRGV-YMFR 4828
K + RSRI GL+A I MVIEY+G IR VA+ +EK Y + G Y+FR
Sbjct: 1567 KKKLRFGRSRIHEWGLFAMEPIAADEMVIEYVGQNIRQMVADMREKRYVQEGIGSSYLFR 1626
Query: 4829 MDNDHVIDATLTGGPARYINHSCAPNCVAEVVTFERGHKIIISSSRRIQKGEELCYDYKF 4888
+D+D +IDAT G AR+INH C PNC A+V+T E KI+I S + I EE+ YDYKF
Sbjct: 1627 VDHDTIIDATKCGNLARFINHCCTPNCYAKVITIESQKKIVIYSKQPIGVDEEITYDYKF 1686
Query: 4889 DFEDDQHKIPCHCGAVNCRKWMN 4911
ED +KIPC CG +CR +N
Sbjct: 1687 PLED--NKIPCLCGTESCRGSLN 1707
Score = 48.1 bits (113), Expect = 2e-04
Identities = 102/470 (21%), Positives = 154/470 (32%), Gaps = 73/470 (15%)
Query: 1796 QSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAPPP 1855
+S SDT + + PGNG + F+ TP+S PQ+
Sbjct: 219 RSSSDTAAYPAGTTAVGTPGNGTPCSQDTS----FSSSRQDTPSSFGQ----FTPQSSQG 270
Query: 1856 PPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFS 1915
P SR S A +S S S NS + FS
Sbjct: 271 TPYTSRGSTPYSQDSAYSSSTTSTSFKPRRSENSYQDA--------------------FS 310
Query: 1916 RRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMT 1975
RR+ +A + T ++++ +++ S + SSS++++ + D P
Sbjct: 311 RRHFSASSASTTASTAIAATTAATASSSASSSSLSSSSSSSSSSSSSQFRSSDANYPAYY 370
Query: 1976 DQFPKSLGLSRSP---VVSEQTAKGPIAAGTSDHF-------TKPSPRADVFQRQRIPDS 2025
+ + + + P E+ P A T++ F P P Q R P S
Sbjct: 371 ESWNRYQRHTSYPPRRATREEPPGAPFAENTAERFPPSYTSYLPPEPSRPTDQDYRPPAS 430
Query: 2026 YARPLLTPAPLDSGPGPFKTP------MQPPPSSQDPYGSVSQASRRLSVDPYERPALTP 2079
A P P P G G +P P P+S GS + + SV P+ + +
Sbjct: 431 EAPPPEPPEPGGGGGGGGPSPEREEVRTSPRPASPARSGSPAPETTNESV-PFAQHSSLD 489
Query: 2080 RPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSR-------AFSQPGTISRPTSQDPY- 2131
I+ Q + T N S +R + S G + P + +
Sbjct: 490 SRIEMLLKEQRSKFSFLASDTEEEEENSSMVLGARDTGSEVPSGSGHGPCTPPPAPANFE 549
Query: 2132 ------SQPPGTPR--PVVDSYSQSSGTAR------SNTDPYSQPPGTPRPTTVDPYSQQ 2177
S PG R P + +Q+S + S+ D PP P P P
Sbjct: 550 DVAPTGSGEPGATRESPKANGQNQASPCSSGDDMEISDDDRGGSPPPAPTPPQQPPPPPP 609
Query: 2178 PQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRP 2227
P P P L P+ H Y P PRP P PP P P
Sbjct: 610 PPPPPPPYLASL---PLGYPPHQPAYLLP---PRPDGPPPPEYPPPPPPP 653
Score = 45.4 bits (106), Expect = 0.001
Identities = 38/200 (19%), Positives = 80/200 (40%), Gaps = 16/200 (8%)
Query: 1718 RQQQQDSIDPSSRIDSELFKDPLKQRESEHEQEWKFRQQMRQKSKQQAKIEATQKLEQVK 1777
+ ++ ++D S+ + + E ++E + R++ +K++ ++ + E
Sbjct: 954 KHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDS 1013
Query: 1778 NEQQQQQQQQFGSQHLLVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPST 1837
+ + G S S + SS S + + + S ++S ++ ++ P+
Sbjct: 1014 SSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAA 1073
Query: 1838 PTSTSSDDVFVKPQAPPPPPAPSRIPIQDSLS----------QAQTSQPPSPQVFSPGSS 1887
S S + P P PAP +P+ + ++ +A ++P P SP S+
Sbjct: 1074 LPSASPPP----REVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSA 1129
Query: 1888 NSRPPSPMDPYAKMVGTPRP 1907
RPP P P PRP
Sbjct: 1130 PLRPPEP--PAGPPAPAPRP 1147
Score = 38.1 bits (87), Expect = 0.22
Identities = 98/507 (19%), Positives = 159/507 (31%), Gaps = 78/507 (15%)
Query: 3514 SFVPDSPSIPVGSPNFSSVKQGHGNLSGT--SFQQSPVRPSFTPALPAAPPVANSSLPCG 3571
S+ P + +P G S QG G + T S ++S + PA A + PC
Sbjct: 187 SYTPQT--VPTGGKALSEKFQGSGAATETAESRRRSSSDTAAYPAGTTAVGTPGNGTPCS 244
Query: 3572 QDSTITH---------GHSYPGSTQ------------SLIQLYSDIIPEEKGKKKRTRKK 3610
QD++ + G P S+Q S YS K +R+
Sbjct: 245 QDTSFSSSRQDTPSSFGQFTPQSSQGTPYTSRGSTPYSQDSAYSSSTTSTSFKPRRSENS 304
Query: 3611 KRDDDAE----STKAPSTPHSDITAPPTPGISETTSTPAVSTPSELPQQADQESVEPVGP 3666
+D + ++ A +T + I A S + S+ ++S+ S +
Sbjct: 305 YQDAFSRRHFSASSASTTASTAIAATTAATASSSASSSSLSSSSSSSSSSSSSQFRSSDA 364
Query: 3667 STPNMAAGQLCTELENKLPNSDFSQATPNQQTYANSEVDKLSMETPAKTEEIKLEKAETE 3726
+ P + P ++ P +A + ++ P+ T + E +
Sbjct: 365 NYPAYYESWNRYQRHTSYPPRRATREEPPGAPFAENTAERFP---PSYTSYLPPEPSRPT 421
Query: 3727 SC----PGQEEPKLEEQNGSKVEGNAVACPVSSAQSPPHSAGAPAAKGDSGNELLKHLLK 3782
P E P E G P +PA G E +
Sbjct: 422 DQDYRPPASEAPPPEPPEPGGGGGGGGPSPEREEVRTSPRPASPARSGSPAPETTNESVP 481
Query: 3783 NKKSSSL--------LNQKPEGSICSEDDCTKDNKLVEKQNPAEGLQTLGAQMQGGFGCG 3834
+ SSL Q+ + S + D T++ + E + G + G+++ G G G
Sbjct: 482 FAQHSSLDSRIEMLLKEQRSKFSFLASD--TEEEE--ENSSMVLGARDTGSEVPSGSGHG 537
Query: 3835 NQLPKTDGGSETKKQRSKRTQRTGEKAAPRSKKRKKDEEEKQAMYSSTDTFTHLKQQNNL 3894
P T + + T +GE A R + + + S D +
Sbjct: 538 ---PCTPPPAPANFEDVAPTG-SGEPGATRESPKANGQNQASPCSSGDDMEISDDDRGGS 593
Query: 3895 SNP-PTPPASLPPTPPPMACQKMANGFATTEELAGKAGVLVSHEVTKTLGPKPFQLPFRP 3953
P PTPP PP PPP LA H+ L P+P
Sbjct: 594 PPPAPTPPQQPPPPPPPPP--------PPPPYLASLPLGYPPHQPAYLLPPRP------- 638
Query: 3954 QDDLLARALAQGPKTVDVPASLPTPPH 3980
GP + P P PPH
Sbjct: 639 ----------DGPPPPEYPPPPPPPPH 655
Score = 37.7 bits (86), Expect = 0.28
Identities = 46/200 (23%), Positives = 66/200 (33%), Gaps = 60/200 (30%)
Query: 1759 QKSKQQAKIEATQKLEQVK--------NEQQQQQQQQFGSQHLLVQSGSDTPSSGIQSPL 1810
Q S ++IE K ++ K E+++ G++ +GS+ PS P
Sbjct: 484 QHSSLDSRIEMLLKEQRSKFSFLASDTEEEEENSSMVLGAR----DTGSEVPSGSGHGPC 539
Query: 1811 TPQPGNGNMS---------PAQSFHKELFTKQPPSTPTSTSSDDVFVK------------ 1849
TP P N P + Q ++P S S DD+ +
Sbjct: 540 TPPPAPANFEDVAPTGSGEPGATRESPKANGQNQASPCS-SGDDMEISDDDRGGSPPPAP 598
Query: 1850 ----------PQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYA 1899
P PPPPP + +P+ Q PP P PP P P
Sbjct: 599 TPPQQPPPPPPPPPPPPPYLASLPLGYPPHQPAYLLPPRP---------DGPPPPEYP-- 647
Query: 1900 KMVGTPRPPPVGHSFSRRNS 1919
P PPP H + NS
Sbjct: 648 -----PPPPPPPHIYDFVNS 662
Score = 37.7 bits (86), Expect = 0.28
Identities = 28/123 (22%), Positives = 54/123 (43%), Gaps = 6/123 (4%)
Query: 3 SEEDKSVEQPQPPPPPPEEPGAPAPSPAAADKRPRGRPRKDGASPFQRARKKPRSRGKTA 62
SE ++ E+ +P P P E P ++ G P + G P +R ++ +++GK
Sbjct: 901 SEISEASEEKRPRPSTPAEEDEDDPE----QEKEAGEPGRPGTKPPKRDEERGKTQGKHR 956
Query: 63 VEDEDSMDGLETTETETIVETEIKEQSAEEDAEAE--VDNSKQLIPTLQRSVSEESANSL 120
+G E ++ + + E ++ EED + E VD +K+ E ++S
Sbjct: 957 KSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSK 1016
Query: 121 VSV 123
S+
Sbjct: 1017 CSL 1019
Score = 37.4 bits (85), Expect = 0.37
Identities = 36/151 (23%), Positives = 58/151 (38%), Gaps = 7/151 (4%)
Query: 2794 PKKKEQENKTLVLSDKHSPQKKSTVTNEVKTEVLSPNSKVESKCETEKNDENKDNVDTPC 2853
PK+ E+ KT KH E ++ S E E E++++ ++ VDT
Sbjct: 942 PKRDEERGKT---QGKHRKSFALDSEGEEASQESSSEKDEEDDEEDEEDEDREEAVDTTK 998
Query: 2854 SQASAHSDLNDGEKTSLHPCDPDLFEKRTNRETAGPSANVIQASTQLPAQDVINSCGITG 2913
+ SD D E S C N T+ ++ +S+ + +S +
Sbjct: 999 KETEV-SDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSS 1057
Query: 2914 STPVLSSLLANEKSDNSDIRPSGSPPPPTLP 2944
S SS E+ + PS SPPP +P
Sbjct: 1058 SE---SSSEDEEEEERPAALPSASPPPREVP 1085
Score = 36.6 bits (83), Expect = 0.63
Identities = 77/383 (20%), Positives = 134/383 (34%), Gaps = 43/383 (11%)
Query: 1686 SSQERAPYVQKARDNRAALRINKVQMSNDSMKRQQQQDSIDPSSRIDSE--LFKDPLKQR 1743
+SQE + + D ++ + + + K + D D S S+ L+ D +
Sbjct: 968 ASQESSSEKDEEDDEEDEEDEDREEAVDTTKKETEVSDGEDEESDSSSKCSLYADSDGEN 1027
Query: 1744 ESEHEQEWKFRQQMRQKSKQQAKIEATQKLEQVKNEQQQQQQQQFGSQHLLVQSGSDTPS 1803
+S + E S + ++ + +E ++++++ + S S P
Sbjct: 1028 DSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESSSEDEEEEERPAA-----LPSASPPPR 1082
Query: 1804 S-GIQSPL---TPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAPPP-PPA 1858
+ +P P P SP ++ + P+ PT S ++P PP PPA
Sbjct: 1083 EVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPARPAGPTEESPPSAPLRPPEPPAGPPA 1142
Query: 1859 PSRIPIQDSLSQAQTSQPPSPQVFSPGSS------NSRPPSPMDPYAKMVG-TPRPPPVG 1911
P+ P + S PP + + S PP P AK G R P G
Sbjct: 1143 PAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVVPAPEPPPATPPQAKFPGPASRKAPRG 1202
Query: 1912 HSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPR 1971
+ RN P+++ + + S + +R R T + +
Sbjct: 1203 VERTIRN--LPLDHASLVKSWPEEV-------SRGGRSRAGGRGRLTEEEEAEPGTEVDL 1253
Query: 1972 PVMTD--QFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARP 2029
V+ D P GL P V + A TSD +P P + + +YA
Sbjct: 1254 AVLADLALTPARRGLPALPAVEDSE-----ATETSDEAERPRP---LLSHILLEHNYAL- 1304
Query: 2030 LLTPAPLDSGPGPFKTPMQPPPS 2052
+ P P P P P +P P+
Sbjct: 1305 AVKPTP----PAPALRPPEPVPA 1323
Score = 36.2 bits (82), Expect = 0.82
Identities = 32/109 (29%), Positives = 42/109 (38%), Gaps = 21/109 (19%)
Query: 3278 PTMMPSVQPQPPLIPGATPPTMSQPTFPMVPQQLQHQQHTTVISGHTSPVRMPSLPGWQP 3337
P +PS P P +P TP + P VP+++ T + SP R P
Sbjct: 1071 PAALPSASPPPREVPVPTPAPVEVP----VPERVAGSPVTPLPEQEASPARPAGPTEESP 1126
Query: 3338 NSAPAHLPLNPPRIQPPIAQLPIKTCTPAPGTVSNANPQSG----PPPR 3382
SA PL PP +PP PAP + P S PPP+
Sbjct: 1127 PSA----PLRPP--EPPAG-------PPAPAPRPDERPSSPIPLLPPPK 1162
Score = 35.0 bits (79), Expect = 1.8
Identities = 28/112 (25%), Positives = 48/112 (42%), Gaps = 20/112 (17%)
Query: 3 SEEDKSVEQPQPPPPPPEEP----GAPAPSPAAADKRPRGRPRKDGASPFQRARKKPRSR 58
+++D + PPP P EP G PSP + R RP ASP + P +
Sbjct: 421 TDQDYRPPASEAPPPEPPEPGGGGGGGGPSPEREEVRTSPRP----ASPARSGSPAPET- 475
Query: 59 GKTAVEDEDSMDGLETTETETIVETEIKEQSAE-----EDAEAEVDNSKQLI 105
+S+ + + ++ +E +KEQ ++ D E E +NS ++
Sbjct: 476 ------TNESVPFAQHSSLDSRIEMLLKEQRSKFSFLASDTEEEEENSSMVL 521
Score = 34.3 bits (77), Expect = 3.1
Identities = 39/179 (21%), Positives = 70/179 (39%), Gaps = 16/179 (8%)
Query: 2814 KKSTVTNEVKTEVLSPNSKVESKCETE-KNDENKDNVDTPCSQASAHSDLNDGEKTSLHP 2872
KK T ++ + E +SK +++ +ND D+ + S +S+ S + +S
Sbjct: 998 KKETEVSDGEDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSSSSSSSSSSSSS 1057
Query: 2873 CDPDLF-EKRTNRETAGPSANV--------IQASTQLPAQDVINSCGITG-----STPVL 2918
+ E+ R A PSA+ A ++P + + +T ++P
Sbjct: 1058 SESSSEDEEEEERPAALPSASPPPREVPVPTPAPVEVPVPERVAGSPVTPLPEQEASPAR 1117
Query: 2919 SSLLANEKSDNSDIRPSGSPPPPTLPA-SPSNHVSSLPPFIAPPGRVLDNAMNSNVTVV 2976
+ E ++ +RP P P PA P SS P + PP + S + VV
Sbjct: 1118 PAGPTEESPPSAPLRPPEPPAGPPAPAPRPDERPSSPIPLLPPPKKRRKTVSFSAIEVV 1176
Score = 33.5 bits (75), Expect = 5.3
Identities = 43/162 (26%), Positives = 64/162 (39%), Gaps = 7/162 (4%)
Query: 718 ERLQGEKEQKENSELSTGLMDSEMTPTIEGCVKDVSYQGGKSIKLSSETESSFSSSADIS 777
+R + K+ +E+S G + E + + C G SE+ SS SSS+ S
Sbjct: 989 DREEAVDTTKKETEVSDG--EDEESDSSSKCSLYADSDGENDSTSDSESSSSSSSSSSSS 1046
Query: 778 KADVSSSPTPSSDLPSHD-MLHNYPSALSSSAGNIMPTTYISVTPKIGMGKPAITKRKFS 836
+ SSS + SS+ S D P+AL S++ P + V + P + S
Sbjct: 1047 SSSSSSSSSSSSESSSEDEEEEERPAALPSAS---PPPREVPVPTPAPVEVPVPERVAGS 1103
Query: 837 PGRPRSKQGAWSTHNTVSPPSWSPDISEGREIFKPRQLPGSA 878
P P +Q A S P SP + R P P A
Sbjct: 1104 PVTPLPEQEA-SPARPAGPTEESPPSAPLRPPEPPAGPPAPA 1144
Score = 33.1 bits (74), Expect = 7.0
Identities = 90/420 (21%), Positives = 131/420 (31%), Gaps = 56/420 (13%)
Query: 2084 NFSHNQSNDPYSQPPLTPHPAVNESF-AHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVV 2142
+FS ++ + P S TP + + + S +SQ S T+ + PR
Sbjct: 248 SFSSSRQDTPSSFGQFTPQSSQGTPYTSRGSTPYSQDSAYSSSTTSTSFK-----PRRSE 302
Query: 2143 DSYSQSSGTARSNTDPYSQPPGTP-RPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSD 2201
+SY + + S T TT S + S+ + + ++Q S
Sbjct: 303 NSYQDAFSRRHFSASSASTTASTAIAATTAATASSSASSSSLSSSSSSSSSSSSSQFRSS 362
Query: 2202 PYAHPP----------GTPRPGISVPYSQPPATPRPRISEGFTRSSMTRPVLMPNQDPFL 2251
+P T P +PP P F ++ R P+ +L
Sbjct: 363 DANYPAYYESWNRYQRHTSYPPRRATREEPPGAP-------FAENTAER--FPPSYTSYL 413
Query: 2252 QAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTP-RSQS 2310
+R RPP + + P PP PG SP P +P RS S
Sbjct: 414 PPEPSRPTDQD---YRPPASEAPPPEPPEPGGGGGGGGPSPEREEVRTSPRPASPARSGS 470
Query: 2311 DSFGTSQTA-----HDVADQ------PRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPV 2359
+ T+ + H D S+ SF AS G V
Sbjct: 471 PAPETTNESVPFAQHSSLDSRIEMLLKEQRSKFSFLASDTEEEEENSSMVLGARDTGSEV 530
Query: 2360 PTSGVTDTQNTVNMAQADTEKLRQ---------RQKLREIILQQQQQKKIAGRQEKGSQD 2410
P SG T A A+ E + R+ + Q E D
Sbjct: 531 P-SGSGHGPCTPPPAPANFEDVAPTGSGEPGATRESPKANGQNQASPCSSGDDMEISDDD 589
Query: 2411 SPAVPHPGPLQHWQPENVNQAFTRPPPPYPGNIRSPVA-PPLGPRYAVFPKDQRGPYPPD 2469
P P P QP PPPP P P+ PP P Y + P+ GP PP+
Sbjct: 590 RGGSPPPAPTPPQQPPPPPPP---PPPPPPYLASLPLGYPPHQPAYLLPPRPD-GPPPPE 645
>gi|205830434 D4, zinc and double PHD fingers family 1 isoform c [Homo
sapiens]
Length = 332
Score = 95.9 bits (237), Expect = 9e-19
Identities = 40/100 (40%), Positives = 57/100 (57%), Gaps = 4/100 (4%)
Query: 960 CVVC--GSFGQGAEGRLLACSQCGQCYHPYCV--SIKITKVVLSKGWRCLECTVCEACGK 1015
C C GS G L++C+ CG+ HP C+ ++ +T V + W+C+EC C CG
Sbjct: 219 CDFCLGGSKKTGCPEDLISCADCGRSGHPSCLQFTVNMTAAVRTYRWQCIECKSCSLCGT 278
Query: 1016 ATDPGRLLLCDDCDISYHTYCLDPPLQTVPKGGWKCKWCV 1055
+ + +LL CDDCD YH YCL PP+ P+G W C C+
Sbjct: 279 SENDDQLLFCDDCDRGYHMYCLSPPMAEPPEGSWSCHLCL 318
Score = 80.9 bits (198), Expect = 3e-14
Identities = 36/89 (40%), Positives = 44/89 (49%), Gaps = 6/89 (6%)
Query: 350 PGDLLDQFFCTTCGQHYHGMCLDIAVT---PLKRAGWQCPECKVCQNCKQSGEDSKMLVC 406
P DL+ C CG+ H CL V ++ WQC ECK C C S D ++L C
Sbjct: 232 PEDLIS---CADCGRSGHPSCLQFTVNMTAAVRTYRWQCIECKSCSLCGTSENDDQLLFC 288
Query: 407 DTCDKGYHTFCLQPVMKSVPTNGWKCKNC 435
D CD+GYH +CL P M P W C C
Sbjct: 289 DDCDRGYHMYCLSPPMAEPPEGSWSCHLC 317
Score = 36.6 bits (83), Expect = 0.63
Identities = 26/116 (22%), Positives = 39/116 (33%), Gaps = 36/116 (31%)
Query: 388 CKVCQN-CKQSGEDSKMLVCDTCDKGYHTFCLQPVMK---SVPTNGWKCKNCRICIECGT 443
C C K++G ++ C C + H CLQ + +V T W+C C+ C CGT
Sbjct: 219 CDFCLGGSKKTGCPEDLISCADCGRSGHPSCLQFTVNMTAAVRTYRWQCIECKSCSLCGT 278
Query: 444 RSSSQWHHNCLICDNCYQQQDNLCPFCGKCYHPELQKDMLHCNMCKRWVHLECDKP 499
+ +L C+ C R H+ C P
Sbjct: 279 SENDD--------------------------------QLLFCDDCDRGYHMYCLSP 302
>gi|205830430 D4, zinc and double PHD fingers family 1 isoform a [Homo
sapiens]
Length = 414
Score = 95.9 bits (237), Expect = 9e-19
Identities = 40/100 (40%), Positives = 57/100 (57%), Gaps = 4/100 (4%)
Query: 960 CVVC--GSFGQGAEGRLLACSQCGQCYHPYCV--SIKITKVVLSKGWRCLECTVCEACGK 1015
C C GS G L++C+ CG+ HP C+ ++ +T V + W+C+EC C CG
Sbjct: 301 CDFCLGGSKKTGCPEDLISCADCGRSGHPSCLQFTVNMTAAVRTYRWQCIECKSCSLCGT 360
Query: 1016 ATDPGRLLLCDDCDISYHTYCLDPPLQTVPKGGWKCKWCV 1055
+ + +LL CDDCD YH YCL PP+ P+G W C C+
Sbjct: 361 SENDDQLLFCDDCDRGYHMYCLSPPMAEPPEGSWSCHLCL 400
Score = 80.9 bits (198), Expect = 3e-14
Identities = 36/89 (40%), Positives = 44/89 (49%), Gaps = 6/89 (6%)
Query: 350 PGDLLDQFFCTTCGQHYHGMCLDIAVT---PLKRAGWQCPECKVCQNCKQSGEDSKMLVC 406
P DL+ C CG+ H CL V ++ WQC ECK C C S D ++L C
Sbjct: 314 PEDLIS---CADCGRSGHPSCLQFTVNMTAAVRTYRWQCIECKSCSLCGTSENDDQLLFC 370
Query: 407 DTCDKGYHTFCLQPVMKSVPTNGWKCKNC 435
D CD+GYH +CL P M P W C C
Sbjct: 371 DDCDRGYHMYCLSPPMAEPPEGSWSCHLC 399
Score = 36.6 bits (83), Expect = 0.63
Identities = 26/116 (22%), Positives = 39/116 (33%), Gaps = 36/116 (31%)
Query: 388 CKVCQN-CKQSGEDSKMLVCDTCDKGYHTFCLQPVMK---SVPTNGWKCKNCRICIECGT 443
C C K++G ++ C C + H CLQ + +V T W+C C+ C CGT
Sbjct: 301 CDFCLGGSKKTGCPEDLISCADCGRSGHPSCLQFTVNMTAAVRTYRWQCIECKSCSLCGT 360
Query: 444 RSSSQWHHNCLICDNCYQQQDNLCPFCGKCYHPELQKDMLHCNMCKRWVHLECDKP 499
+ +L C+ C R H+ C P
Sbjct: 361 SENDD--------------------------------QLLFCDDCDRGYHMYCLSP 384
>gi|19923202 enhancer of zeste homolog 1 [Homo sapiens]
Length = 747
Score = 94.0 bits (232), Expect = 3e-18
Identities = 46/123 (37%), Positives = 72/123 (58%), Gaps = 1/123 (0%)
Query: 4770 KSNVYLARSRIQGLGLYAARDIEKHTMVIEYIGTIIRNEVANRKEKLYESQNRGVYMFRM 4829
K ++ LA S + G G + ++K+ + EY G +I + A+R+ K+Y+ ++F +
Sbjct: 612 KKHLLLAPSDVAGWGTFIKESVQKNEFISEYCGELISQDEADRRGKVYDKYMSS-FLFNL 670
Query: 4830 DNDHVIDATLTGGPARYINHSCAPNCVAEVVTFERGHKIIISSSRRIQKGEELCYDYKFD 4889
+ND V+DAT G R+ NHS PNC A+VV H+I I + R IQ GEEL +DY++
Sbjct: 671 NNDFVVDATRKGNKIRFANHSVNPNCYAKVVMVNGDHRIGIFAKRAIQAGEELFFDYRYS 730
Query: 4890 FED 4892
D
Sbjct: 731 QAD 733
>gi|23510384 enhancer of zeste 2 isoform b [Homo sapiens]
Length = 707
Score = 92.8 bits (229), Expect = 7e-18
Identities = 46/123 (37%), Positives = 73/123 (59%), Gaps = 1/123 (0%)
Query: 4770 KSNVYLARSRIQGLGLYAARDIEKHTMVIEYIGTIIRNEVANRKEKLYESQNRGVYMFRM 4829
K ++ LA S + G G++ ++K+ + EY G II + A+R+ K+Y+ ++F +
Sbjct: 572 KKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCS-FLFNL 630
Query: 4830 DNDHVIDATLTGGPARYINHSCAPNCVAEVVTFERGHKIIISSSRRIQKGEELCYDYKFD 4889
+ND V+DAT G R+ NHS PNC A+V+ H+I I + R IQ GEEL +DY++
Sbjct: 631 NNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYS 690
Query: 4890 FED 4892
D
Sbjct: 691 QAD 693
>gi|21361095 enhancer of zeste 2 isoform a [Homo sapiens]
Length = 751
Score = 92.8 bits (229), Expect = 7e-18
Identities = 46/123 (37%), Positives = 73/123 (59%), Gaps = 1/123 (0%)
Query: 4770 KSNVYLARSRIQGLGLYAARDIEKHTMVIEYIGTIIRNEVANRKEKLYESQNRGVYMFRM 4829
K ++ LA S + G G++ ++K+ + EY G II + A+R+ K+Y+ ++F +
Sbjct: 616 KKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIISQDEADRRGKVYDKYMCS-FLFNL 674
Query: 4830 DNDHVIDATLTGGPARYINHSCAPNCVAEVVTFERGHKIIISSSRRIQKGEELCYDYKFD 4889
+ND V+DAT G R+ NHS PNC A+V+ H+I I + R IQ GEEL +DY++
Sbjct: 675 NNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHRIGIFAKRAIQTGEELFFDYRYS 734
Query: 4890 FED 4892
D
Sbjct: 735 QAD 737
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 91.3 bits (225), Expect = 2e-17
Identities = 137/635 (21%), Positives = 210/635 (33%), Gaps = 90/635 (14%)
Query: 1768 EATQKLEQVKNEQQQQQQQQFGSQHLLVQSGSD-TPSSGIQSPLTPQPGNGNMSPAQSFH 1826
E T +Q + +++ +Q + S D P+S + + TP+ PA +
Sbjct: 154 ETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTP 213
Query: 1827 KE---LFTKQPPST------PTSTSSDDVFVKPQAP---------PPPPAPSRI----PI 1864
KE K+P ST PT+ S K AP P PAP+ P
Sbjct: 214 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 273
Query: 1865 QDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNSAAPVE 1924
T++ P+P + + P+P P TP+ P + + P
Sbjct: 274 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEP----APTTPKEPTPTT 329
Query: 1925 NCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTDQFPKSLGL 1984
P + P TT P+P + TT +P P P P T + +
Sbjct: 330 PKEPAPTTKEPA---PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK 386
Query: 1985 SRSPVVSEQ---TAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLLT----PAPLD 2037
+P ++ T K P T T P + ++ P + P T PAP
Sbjct: 387 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT 446
Query: 2038 SGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQP 2097
TP +P P++ + + P E TP+ + P
Sbjct: 447 PKEPAPTTPKEPAPTTTKK-PAPTTPKEPAPTTPKETAPTTPKKL------TPTTPEKLA 499
Query: 2098 PLTPH---PAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPR---------PVVDSY 2145
P TP P E A + P T P P + P TP+ P +
Sbjct: 500 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 559
Query: 2146 SQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTP-----RPSTQTDLFVTPVTNQRHS 2200
+ + T T P + P GT T +P P+ P P+T + T +
Sbjct: 560 KEPAPTTPKETAP-TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 618
Query: 2201 DPYAHPPGTPR-PGISVPYSQPPATPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRGP 2259
P P TP+ P + P P TP+ + T P ++ L +GP
Sbjct: 619 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKE--LAPTTTKGP 676
Query: 2260 A-----LPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQSDSFG 2314
P P P +T TP+ P +P+ + P +P TP +
Sbjct: 677 TSTTSDKPAP-TTPKETAPTTPKEP-----------APTTPKKPAPTTPETPPPTTSEVS 724
Query: 2315 TSQTA------HDVADQPRP--GSEGSFCASSNSP 2341
T T H D+ P +E + A NSP
Sbjct: 725 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP 759
Score = 48.5 bits (114), Expect = 2e-04
Identities = 110/580 (18%), Positives = 183/580 (31%), Gaps = 70/580 (12%)
Query: 3518 DSPSIPVGSPNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAAPPVAN-SSLPCGQDSTI 3576
D+ V +P+ S+ + + S P+ P P+LP + +SL +++T+
Sbjct: 93 DNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR--PSLPPNSDTSKETSLTVNKETTV 150
Query: 3577 THGHSYPGSTQSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTKAPSTPHSDITAPPTPG 3636
+ + Q+ GK+K T K+ +++ P S + A PTP
Sbjct: 151 ETKETTTTNKQT----------STDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPK 200
Query: 3637 ISETTSTPAVSTPSELPQQADQESVEPVGPSTPNMAAGQLCTELENKLPNSDFSQATPNQ 3696
TT PA++TP E P+TP A T E + TP +
Sbjct: 201 AETTTKGPALTTPKE------------PTPTTPKEPAS--TTPKEPTPTTIKSAPTTPKE 246
Query: 3697 QTYANSEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVEGNAVACPVSSA 3756
++ + + PA T K + P + P ++ +A P A
Sbjct: 247 PAPTTTKSAPTTPKEPAPT----TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA 302
Query: 3757 QSPPHSAGAPAAKGDSGNELLKHLLKNKKSSSLLNQKPEGSICSEDDCTKDNKLVEKQNP 3816
+ P K + + K + ++P + E T K P
Sbjct: 303 PTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKK-PAPTTP 361
Query: 3817 AEGLQTLGAQMQGGFGCGNQLPKTDGGSETKKQRSKRTQRTGEKAAPRSKKRKKDEEEKQ 3876
E T + P E K T K+AP + K K
Sbjct: 362 KEPAPTTPKE-----------PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKS 410
Query: 3877 AMYSSTDTFTHLKQQNNLSNPPTPPASLPPTPPPMACQKMANGFATTEELAGKAGVLVSH 3936
A + + ++ + P P + P P P ++ A T +E A
Sbjct: 411 APTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP--TTPKEPA--------- 459
Query: 3937 EVTKTLGPKPF----QLPFRPQDDLLARALAQGPKTVD--VPASLPTPPHNNQEELRIQD 3990
T T P P P P++ P T + P + P EEL
Sbjct: 460 -PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA--- 515
Query: 3991 HCGDRDTPDSFVPSSSPESVVGVEVSRYPDLSLVKEEPPEPVPSPIIPILPSTAGKSSES 4050
TP+ P++ E + P+ P+P P P+ +
Sbjct: 516 ----PTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA 571
Query: 4051 RRNDIKTEPGTLYFASPFGPSPNGPRSGLISVAITLHPTA 4090
T P TL +P P P+ ++ T PT+
Sbjct: 572 PTTPKGTAPTTLKEPAPTTPKKPAPKE--LAPTTTKEPTS 609
Score = 40.4 bits (93), Expect = 0.044
Identities = 96/469 (20%), Positives = 153/469 (32%), Gaps = 55/469 (11%)
Query: 3547 SPVRPSFTPALPAAPPVANSSLPCGQDST-ITHGHSYPGSTQSLIQLYSDIIPEEKGKKK 3605
+P P+ T +P P S T P +T+S + P +
Sbjct: 368 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA 427
Query: 3606 RTRKKKRDDDAESTKAPSTPHSDITAPPTPGISETTSTPAVSTPSE----LPQQADQESV 3661
T K+ AP+TP P TT PA +TP E P++ +
Sbjct: 428 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 487
Query: 3662 EPVGPSTPNMAAGQLCTELENKLPNS--DFSQATPNQQTYANSEVDKLSMETPAKTEEIK 3719
+ + P+TP A T E P + + + TP + T + E PA T K
Sbjct: 488 KKLTPTTPEKLAP---TTPEKPAPTTPEELAPTTPEEPT-------PTTPEEPAPTTP-K 536
Query: 3720 LEKAETESCPGQEEPKLEEQNGSKVEGNAVACPVSSAQSPPHSAGAPAAKGDSGNELLKH 3779
T P PK E + + A P +A + P K + K
Sbjct: 537 AAAPNTPKEPAPTTPK--EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 594
Query: 3780 LLKNKKSSSLLNQKPEGSICSEDDCTKDNKLVEKQNPAEGLQTLGAQMQGGFGCGNQLPK 3839
K+ + ++P + C + T K P E T + P
Sbjct: 595 --APKELAPTTTKEPTSTTCDKPAPTTP-KGTAPTTPKEPAPTTPKE---------PAPT 642
Query: 3840 TDGGS--ETKKQRSKRTQR---TGEKAAPRSKKRKKDEEEKQAMYSSTDTFTHLKQQNNL 3894
T G+ T K+ + T + E A +K +K A + +T ++
Sbjct: 643 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP 702
Query: 3895 SNPPTPPASLPPTPPPMACQKMANGFATTEELAGKAGVLVSHEVTKTLGPKPFQLPFRPQ 3954
+ P P + P TPPP TT E++ + K+ +L P
Sbjct: 703 TTPKKPAPTTPETPPP-----------TTSEVSTPTTTKEPTTIHKSPDESTPELSAEP- 750
Query: 3955 DDLLARALAQGPKTVDVPASLPTPPHNNQEELRIQDHCGDRD---TPDS 4000
+AL PK VP + + +D +RD TP++
Sbjct: 751 ---TPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPET 796
Score = 40.0 bits (92), Expect = 0.057
Identities = 121/622 (19%), Positives = 173/622 (27%), Gaps = 93/622 (14%)
Query: 3512 PPSFVPDSPSIPVGSPNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAAPPVANSSLPCG 3571
P P +P P + + T + +P P P P + P
Sbjct: 213 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP-- 270
Query: 3572 QDSTITHGHSYPGSTQSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTKAPSTPHSDI-T 3630
+ T P +T+ + P + T KK AP+TP T
Sbjct: 271 --APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPT 328
Query: 3631 APPTPGISETTSTPAVSTPSE----LPQQADQESVEPVGPSTPNMAAGQLCTELENKLPN 3686
P P + TT PA +TP E P++ + + P+TP A E P
Sbjct: 329 TPKEP--APTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK 386
Query: 3687 SDFSQATPNQQTYANSEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVEG 3746
T + T + P +E T P PK K
Sbjct: 387 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE---PSPTTTKEPAPTTPKEPAPTTPKKPA 443
Query: 3747 NAVACPVSSAQSPPHSAGAPAAKGDSGNELLKHLLKNKKSSSLLNQKPEGSICSEDDCTK 3806
P + + P + PA KK + ++P + E T
Sbjct: 444 -----PTTPKEPAPTTPKEPAPT------------TTKKPAPTTPKEPAPTTPKETAPTT 486
Query: 3807 DNKLV----EKQNPAEGLQTLGAQMQGGFGCGNQLPKTDGGSETKKQRSKRTQRTGEKAA 3862
KL EK P + + +L T T + T + AA
Sbjct: 487 PKKLTPTTPEKLAPTTPEKPAPTTPE-------ELAPTTPEEPTPTTPEEPAPTTPKAAA 539
Query: 3863 PRSKKRKKDEEEKQAMYSSTDTFTHLKQQNNLSNPPTPPASLPPTPPPMACQKMANGFAT 3922
P + K K+ PT P PT P G A
Sbjct: 540 PNTPKEPAPTTPKEPA-------------------PTTPKEPAPTTPKETAPTTPKGTAP 580
Query: 3923 TEELAGKAGVLVSHEVTKTLGPKPFQLPFRPQDDLLARALAQG--PKTVDVPASLPTPPH 3980
T L A K L P + P D A +G P T PA PT P
Sbjct: 581 TT-LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA--PTTPK 637
Query: 3981 NNQEELRIQDHCGDRDTPDSFVPSSSPESVVGVEVSRYPDLSLVKEEPPEPVPSPIIPIL 4040
TP P++ E P +P P + P
Sbjct: 638 EPAPT-----------TPKGTAPTTLKEPA--------------PTTPKKPAPKELAPT- 671
Query: 4041 PSTAGKSSESRRNDIKTEPGTLYFASPFGPSPNGPRSGLISVAITLHPTAAENISSVVAA 4100
+T G +S + T P +P P+P P+ + T PT +E +
Sbjct: 672 -TTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTK 730
Query: 4101 FSDLLHVRIPNSYEVSSAPDVP 4122
+H S SA P
Sbjct: 731 EPTTIHKSPDESTPELSAEPTP 752
Score = 35.4 bits (80), Expect = 1.4
Identities = 49/231 (21%), Positives = 89/231 (38%), Gaps = 19/231 (8%)
Query: 2107 ESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTP 2166
ESF + + T +PT + P G+ +D+ T ++T +++ +P
Sbjct: 60 ESFCAEVKDNKKNRTKKKPTPKPPVVDEAGSG---LDNGDFKVTTPDTSTTQHNKVSTSP 116
Query: 2167 RPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPR 2226
+ TT P + +P P P++ T T +T + + T S + + +
Sbjct: 117 KITTAKPINPRPSLP-PNSDTSK-ETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAK 174
Query: 2227 PRISEGFTRSSMTRPVLMPNQDPFLQA-AQNRGPALPGPL----VRPPDTCSQTPRPPGP 2281
S T + P P +A +GPAL P P + S TP+ P P
Sbjct: 175 ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP 234
Query: 2282 GLSDTFSRVSPSAARDP----YDQSPMTPRSQSDSFGTSQTAHDVADQPRP 2328
T + +P+ ++P +P TP+ + + T + A +P P
Sbjct: 235 ----TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPT-TTKEPAPTTPKEPAP 280
Score = 34.7 bits (78), Expect = 2.4
Identities = 60/307 (19%), Positives = 99/307 (32%), Gaps = 34/307 (11%)
Query: 1794 LVQSGSDTPSSGIQSPLTPQPGNGNMS-----PAQSFHKELFTKQP----PSTPTSTSSD 1844
L + TP L P G S PA + KE P P+TP +
Sbjct: 652 LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA-- 709
Query: 1845 DVFVKPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPP-----SPMDPYA 1899
P P PP + + ++ T+ SP +P S P SP +P
Sbjct: 710 -----PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV 764
Query: 1900 KMVGTPRPPPVGHSFSRRNSAAPVE-NCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTT 1958
TP + + ++ + TP ++ + P ET +++TT
Sbjct: 765 PTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTT 824
Query: 1959 NNDPYAKPPDTPRPVMT----------DQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFT 2008
TP + T K++ + E+TAK P T+ T
Sbjct: 825 QVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAK-PKDRATNSKAT 883
Query: 2009 KPSPRADVFQRQRIPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLS 2068
P P+ + + P S +P P P M +P +++A + +
Sbjct: 884 TPKPQKPT-KAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTT 942
Query: 2069 VDPYERP 2075
P + P
Sbjct: 943 TRPNQTP 949
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 91.3 bits (225), Expect = 2e-17
Identities = 137/635 (21%), Positives = 210/635 (33%), Gaps = 90/635 (14%)
Query: 1768 EATQKLEQVKNEQQQQQQQQFGSQHLLVQSGSD-TPSSGIQSPLTPQPGNGNMSPAQSFH 1826
E T +Q + +++ +Q + S D P+S + + TP+ PA +
Sbjct: 195 ETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTP 254
Query: 1827 KE---LFTKQPPST------PTSTSSDDVFVKPQAP---------PPPPAPSRI----PI 1864
KE K+P ST PT+ S K AP P PAP+ P
Sbjct: 255 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 314
Query: 1865 QDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNSAAPVE 1924
T++ P+P + + P+P P TP+ P + + P
Sbjct: 315 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEP----APTTPKEPTPTT 370
Query: 1925 NCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTDQFPKSLGL 1984
P + P TT P+P + TT +P P P P T + +
Sbjct: 371 PKEPAPTTKEPA---PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK 427
Query: 1985 SRSPVVSEQ---TAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLLT----PAPLD 2037
+P ++ T K P T T P + ++ P + P T PAP
Sbjct: 428 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT 487
Query: 2038 SGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQP 2097
TP +P P++ + + P E TP+ + P
Sbjct: 488 PKEPAPTTPKEPAPTTTKK-PAPTTPKEPAPTTPKETAPTTPKKL------TPTTPEKLA 540
Query: 2098 PLTPH---PAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPR---------PVVDSY 2145
P TP P E A + P T P P + P TP+ P +
Sbjct: 541 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 600
Query: 2146 SQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTP-----RPSTQTDLFVTPVTNQRHS 2200
+ + T T P + P GT T +P P+ P P+T + T +
Sbjct: 601 KEPAPTTPKETAP-TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 659
Query: 2201 DPYAHPPGTPR-PGISVPYSQPPATPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRGP 2259
P P TP+ P + P P TP+ + T P ++ L +GP
Sbjct: 660 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKE--LAPTTTKGP 717
Query: 2260 A-----LPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQSDSFG 2314
P P P +T TP+ P +P+ + P +P TP +
Sbjct: 718 TSTTSDKPAP-TTPKETAPTTPKEP-----------APTTPKKPAPTTPETPPPTTSEVS 765
Query: 2315 TSQTA------HDVADQPRP--GSEGSFCASSNSP 2341
T T H D+ P +E + A NSP
Sbjct: 766 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP 800
Score = 48.5 bits (114), Expect = 2e-04
Identities = 110/580 (18%), Positives = 183/580 (31%), Gaps = 70/580 (12%)
Query: 3518 DSPSIPVGSPNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAAPPVAN-SSLPCGQDSTI 3576
D+ V +P+ S+ + + S P+ P P+LP + +SL +++T+
Sbjct: 134 DNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR--PSLPPNSDTSKETSLTVNKETTV 191
Query: 3577 THGHSYPGSTQSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTKAPSTPHSDITAPPTPG 3636
+ + Q+ GK+K T K+ +++ P S + A PTP
Sbjct: 192 ETKETTTTNKQT----------STDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPK 241
Query: 3637 ISETTSTPAVSTPSELPQQADQESVEPVGPSTPNMAAGQLCTELENKLPNSDFSQATPNQ 3696
TT PA++TP E P+TP A T E + TP +
Sbjct: 242 AETTTKGPALTTPKE------------PTPTTPKEPAS--TTPKEPTPTTIKSAPTTPKE 287
Query: 3697 QTYANSEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVEGNAVACPVSSA 3756
++ + + PA T K + P + P ++ +A P A
Sbjct: 288 PAPTTTKSAPTTPKEPAPT----TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA 343
Query: 3757 QSPPHSAGAPAAKGDSGNELLKHLLKNKKSSSLLNQKPEGSICSEDDCTKDNKLVEKQNP 3816
+ P K + + K + ++P + E T K P
Sbjct: 344 PTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKK-PAPTTP 402
Query: 3817 AEGLQTLGAQMQGGFGCGNQLPKTDGGSETKKQRSKRTQRTGEKAAPRSKKRKKDEEEKQ 3876
E T + P E K T K+AP + K K
Sbjct: 403 KEPAPTTPKE-----------PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKS 451
Query: 3877 AMYSSTDTFTHLKQQNNLSNPPTPPASLPPTPPPMACQKMANGFATTEELAGKAGVLVSH 3936
A + + ++ + P P + P P P ++ A T +E A
Sbjct: 452 APTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP--TTPKEPA--------- 500
Query: 3937 EVTKTLGPKPF----QLPFRPQDDLLARALAQGPKTVD--VPASLPTPPHNNQEELRIQD 3990
T T P P P P++ P T + P + P EEL
Sbjct: 501 -PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA--- 556
Query: 3991 HCGDRDTPDSFVPSSSPESVVGVEVSRYPDLSLVKEEPPEPVPSPIIPILPSTAGKSSES 4050
TP+ P++ E + P+ P+P P P+ +
Sbjct: 557 ----PTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA 612
Query: 4051 RRNDIKTEPGTLYFASPFGPSPNGPRSGLISVAITLHPTA 4090
T P TL +P P P+ ++ T PT+
Sbjct: 613 PTTPKGTAPTTLKEPAPTTPKKPAPKE--LAPTTTKEPTS 650
Score = 40.4 bits (93), Expect = 0.044
Identities = 96/469 (20%), Positives = 153/469 (32%), Gaps = 55/469 (11%)
Query: 3547 SPVRPSFTPALPAAPPVANSSLPCGQDST-ITHGHSYPGSTQSLIQLYSDIIPEEKGKKK 3605
+P P+ T +P P S T P +T+S + P +
Sbjct: 409 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA 468
Query: 3606 RTRKKKRDDDAESTKAPSTPHSDITAPPTPGISETTSTPAVSTPSE----LPQQADQESV 3661
T K+ AP+TP P TT PA +TP E P++ +
Sbjct: 469 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 528
Query: 3662 EPVGPSTPNMAAGQLCTELENKLPNS--DFSQATPNQQTYANSEVDKLSMETPAKTEEIK 3719
+ + P+TP A T E P + + + TP + T + E PA T K
Sbjct: 529 KKLTPTTPEKLAP---TTPEKPAPTTPEELAPTTPEEPT-------PTTPEEPAPTTP-K 577
Query: 3720 LEKAETESCPGQEEPKLEEQNGSKVEGNAVACPVSSAQSPPHSAGAPAAKGDSGNELLKH 3779
T P PK E + + A P +A + P K + K
Sbjct: 578 AAAPNTPKEPAPTTPK--EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 635
Query: 3780 LLKNKKSSSLLNQKPEGSICSEDDCTKDNKLVEKQNPAEGLQTLGAQMQGGFGCGNQLPK 3839
K+ + ++P + C + T K P E T + P
Sbjct: 636 --APKELAPTTTKEPTSTTCDKPAPTTP-KGTAPTTPKEPAPTTPKE---------PAPT 683
Query: 3840 TDGGS--ETKKQRSKRTQR---TGEKAAPRSKKRKKDEEEKQAMYSSTDTFTHLKQQNNL 3894
T G+ T K+ + T + E A +K +K A + +T ++
Sbjct: 684 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP 743
Query: 3895 SNPPTPPASLPPTPPPMACQKMANGFATTEELAGKAGVLVSHEVTKTLGPKPFQLPFRPQ 3954
+ P P + P TPPP TT E++ + K+ +L P
Sbjct: 744 TTPKKPAPTTPETPPP-----------TTSEVSTPTTTKEPTTIHKSPDESTPELSAEP- 791
Query: 3955 DDLLARALAQGPKTVDVPASLPTPPHNNQEELRIQDHCGDRD---TPDS 4000
+AL PK VP + + +D +RD TP++
Sbjct: 792 ---TPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPET 837
Score = 40.0 bits (92), Expect = 0.057
Identities = 121/622 (19%), Positives = 173/622 (27%), Gaps = 93/622 (14%)
Query: 3512 PPSFVPDSPSIPVGSPNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAAPPVANSSLPCG 3571
P P +P P + + T + +P P P P + P
Sbjct: 254 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP-- 311
Query: 3572 QDSTITHGHSYPGSTQSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTKAPSTPHSDI-T 3630
+ T P +T+ + P + T KK AP+TP T
Sbjct: 312 --APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPT 369
Query: 3631 APPTPGISETTSTPAVSTPSE----LPQQADQESVEPVGPSTPNMAAGQLCTELENKLPN 3686
P P + TT PA +TP E P++ + + P+TP A E P
Sbjct: 370 TPKEP--APTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK 427
Query: 3687 SDFSQATPNQQTYANSEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVEG 3746
T + T + P +E T P PK K
Sbjct: 428 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE---PSPTTTKEPAPTTPKEPAPTTPKKPA 484
Query: 3747 NAVACPVSSAQSPPHSAGAPAAKGDSGNELLKHLLKNKKSSSLLNQKPEGSICSEDDCTK 3806
P + + P + PA KK + ++P + E T
Sbjct: 485 -----PTTPKEPAPTTPKEPAPT------------TTKKPAPTTPKEPAPTTPKETAPTT 527
Query: 3807 DNKLV----EKQNPAEGLQTLGAQMQGGFGCGNQLPKTDGGSETKKQRSKRTQRTGEKAA 3862
KL EK P + + +L T T + T + AA
Sbjct: 528 PKKLTPTTPEKLAPTTPEKPAPTTPE-------ELAPTTPEEPTPTTPEEPAPTTPKAAA 580
Query: 3863 PRSKKRKKDEEEKQAMYSSTDTFTHLKQQNNLSNPPTPPASLPPTPPPMACQKMANGFAT 3922
P + K K+ PT P PT P G A
Sbjct: 581 PNTPKEPAPTTPKEPA-------------------PTTPKEPAPTTPKETAPTTPKGTAP 621
Query: 3923 TEELAGKAGVLVSHEVTKTLGPKPFQLPFRPQDDLLARALAQG--PKTVDVPASLPTPPH 3980
T L A K L P + P D A +G P T PA PT P
Sbjct: 622 TT-LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA--PTTPK 678
Query: 3981 NNQEELRIQDHCGDRDTPDSFVPSSSPESVVGVEVSRYPDLSLVKEEPPEPVPSPIIPIL 4040
TP P++ E P +P P + P
Sbjct: 679 EPAPT-----------TPKGTAPTTLKEPA--------------PTTPKKPAPKELAPT- 712
Query: 4041 PSTAGKSSESRRNDIKTEPGTLYFASPFGPSPNGPRSGLISVAITLHPTAAENISSVVAA 4100
+T G +S + T P +P P+P P+ + T PT +E +
Sbjct: 713 -TTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTK 771
Query: 4101 FSDLLHVRIPNSYEVSSAPDVP 4122
+H S SA P
Sbjct: 772 EPTTIHKSPDESTPELSAEPTP 793
Score = 35.4 bits (80), Expect = 1.4
Identities = 49/231 (21%), Positives = 89/231 (38%), Gaps = 19/231 (8%)
Query: 2107 ESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTP 2166
ESF + + T +PT + P G+ +D+ T ++T +++ +P
Sbjct: 101 ESFCAEVKDNKKNRTKKKPTPKPPVVDEAGSG---LDNGDFKVTTPDTSTTQHNKVSTSP 157
Query: 2167 RPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPR 2226
+ TT P + +P P P++ T T +T + + T S + + +
Sbjct: 158 KITTAKPINPRPSLP-PNSDTSK-ETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAK 215
Query: 2227 PRISEGFTRSSMTRPVLMPNQDPFLQA-AQNRGPALPGPL----VRPPDTCSQTPRPPGP 2281
S T + P P +A +GPAL P P + S TP+ P P
Sbjct: 216 ETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTP 275
Query: 2282 GLSDTFSRVSPSAARDP----YDQSPMTPRSQSDSFGTSQTAHDVADQPRP 2328
T + +P+ ++P +P TP+ + + T + A +P P
Sbjct: 276 ----TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPT-TTKEPAPTTPKEPAP 321
Score = 34.7 bits (78), Expect = 2.4
Identities = 60/307 (19%), Positives = 99/307 (32%), Gaps = 34/307 (11%)
Query: 1794 LVQSGSDTPSSGIQSPLTPQPGNGNMS-----PAQSFHKELFTKQP----PSTPTSTSSD 1844
L + TP L P G S PA + KE P P+TP +
Sbjct: 693 LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA-- 750
Query: 1845 DVFVKPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPP-----SPMDPYA 1899
P P PP + + ++ T+ SP +P S P SP +P
Sbjct: 751 -----PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV 805
Query: 1900 KMVGTPRPPPVGHSFSRRNSAAPVE-NCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTT 1958
TP + + ++ + TP ++ + P ET +++TT
Sbjct: 806 PTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTT 865
Query: 1959 NNDPYAKPPDTPRPVMT----------DQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFT 2008
TP + T K++ + E+TAK P T+ T
Sbjct: 866 QVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAK-PKDRATNSKAT 924
Query: 2009 KPSPRADVFQRQRIPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLS 2068
P P+ + + P S +P P P M +P +++A + +
Sbjct: 925 TPKPQKPT-KAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTT 983
Query: 2069 VDPYERP 2075
P + P
Sbjct: 984 TRPNQTP 990
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 91.3 bits (225), Expect = 2e-17
Identities = 137/635 (21%), Positives = 210/635 (33%), Gaps = 90/635 (14%)
Query: 1768 EATQKLEQVKNEQQQQQQQQFGSQHLLVQSGSD-TPSSGIQSPLTPQPGNGNMSPAQSFH 1826
E T +Q + +++ +Q + S D P+S + + TP+ PA +
Sbjct: 247 ETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTP 306
Query: 1827 KE---LFTKQPPST------PTSTSSDDVFVKPQAP---------PPPPAPSRI----PI 1864
KE K+P ST PT+ S K AP P PAP+ P
Sbjct: 307 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 366
Query: 1865 QDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNSAAPVE 1924
T++ P+P + + P+P P TP+ P + + P
Sbjct: 367 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEP----APTTPKEPTPTT 422
Query: 1925 NCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTDQFPKSLGL 1984
P + P TT P+P + TT +P P P P T + +
Sbjct: 423 PKEPAPTTKEPA---PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK 479
Query: 1985 SRSPVVSEQ---TAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLLT----PAPLD 2037
+P ++ T K P T T P + ++ P + P T PAP
Sbjct: 480 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT 539
Query: 2038 SGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQP 2097
TP +P P++ + + P E TP+ + P
Sbjct: 540 PKEPAPTTPKEPAPTTTKK-PAPTTPKEPAPTTPKETAPTTPKKL------TPTTPEKLA 592
Query: 2098 PLTPH---PAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPR---------PVVDSY 2145
P TP P E A + P T P P + P TP+ P +
Sbjct: 593 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 652
Query: 2146 SQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTP-----RPSTQTDLFVTPVTNQRHS 2200
+ + T T P + P GT T +P P+ P P+T + T +
Sbjct: 653 KEPAPTTPKETAP-TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 711
Query: 2201 DPYAHPPGTPR-PGISVPYSQPPATPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRGP 2259
P P TP+ P + P P TP+ + T P ++ L +GP
Sbjct: 712 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKE--LAPTTTKGP 769
Query: 2260 A-----LPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQSDSFG 2314
P P P +T TP+ P +P+ + P +P TP +
Sbjct: 770 TSTTSDKPAP-TTPKETAPTTPKEP-----------APTTPKKPAPTTPETPPPTTSEVS 817
Query: 2315 TSQTA------HDVADQPRP--GSEGSFCASSNSP 2341
T T H D+ P +E + A NSP
Sbjct: 818 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP 852
Score = 48.5 bits (114), Expect = 2e-04
Identities = 110/580 (18%), Positives = 183/580 (31%), Gaps = 70/580 (12%)
Query: 3518 DSPSIPVGSPNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAAPPVAN-SSLPCGQDSTI 3576
D+ V +P+ S+ + + S P+ P P+LP + +SL +++T+
Sbjct: 186 DNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR--PSLPPNSDTSKETSLTVNKETTV 243
Query: 3577 THGHSYPGSTQSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTKAPSTPHSDITAPPTPG 3636
+ + Q+ GK+K T K+ +++ P S + A PTP
Sbjct: 244 ETKETTTTNKQT----------STDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPK 293
Query: 3637 ISETTSTPAVSTPSELPQQADQESVEPVGPSTPNMAAGQLCTELENKLPNSDFSQATPNQ 3696
TT PA++TP E P+TP A T E + TP +
Sbjct: 294 AETTTKGPALTTPKE------------PTPTTPKEPAS--TTPKEPTPTTIKSAPTTPKE 339
Query: 3697 QTYANSEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVEGNAVACPVSSA 3756
++ + + PA T K + P + P ++ +A P A
Sbjct: 340 PAPTTTKSAPTTPKEPAPT----TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA 395
Query: 3757 QSPPHSAGAPAAKGDSGNELLKHLLKNKKSSSLLNQKPEGSICSEDDCTKDNKLVEKQNP 3816
+ P K + + K + ++P + E T K P
Sbjct: 396 PTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKK-PAPTTP 454
Query: 3817 AEGLQTLGAQMQGGFGCGNQLPKTDGGSETKKQRSKRTQRTGEKAAPRSKKRKKDEEEKQ 3876
E T + P E K T K+AP + K K
Sbjct: 455 KEPAPTTPKE-----------PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKS 503
Query: 3877 AMYSSTDTFTHLKQQNNLSNPPTPPASLPPTPPPMACQKMANGFATTEELAGKAGVLVSH 3936
A + + ++ + P P + P P P ++ A T +E A
Sbjct: 504 APTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP--TTPKEPA--------- 552
Query: 3937 EVTKTLGPKPF----QLPFRPQDDLLARALAQGPKTVD--VPASLPTPPHNNQEELRIQD 3990
T T P P P P++ P T + P + P EEL
Sbjct: 553 -PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA--- 608
Query: 3991 HCGDRDTPDSFVPSSSPESVVGVEVSRYPDLSLVKEEPPEPVPSPIIPILPSTAGKSSES 4050
TP+ P++ E + P+ P+P P P+ +
Sbjct: 609 ----PTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA 664
Query: 4051 RRNDIKTEPGTLYFASPFGPSPNGPRSGLISVAITLHPTA 4090
T P TL +P P P+ ++ T PT+
Sbjct: 665 PTTPKGTAPTTLKEPAPTTPKKPAPKE--LAPTTTKEPTS 702
Score = 40.4 bits (93), Expect = 0.044
Identities = 96/469 (20%), Positives = 153/469 (32%), Gaps = 55/469 (11%)
Query: 3547 SPVRPSFTPALPAAPPVANSSLPCGQDST-ITHGHSYPGSTQSLIQLYSDIIPEEKGKKK 3605
+P P+ T +P P S T P +T+S + P +
Sbjct: 461 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA 520
Query: 3606 RTRKKKRDDDAESTKAPSTPHSDITAPPTPGISETTSTPAVSTPSE----LPQQADQESV 3661
T K+ AP+TP P TT PA +TP E P++ +
Sbjct: 521 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 580
Query: 3662 EPVGPSTPNMAAGQLCTELENKLPNS--DFSQATPNQQTYANSEVDKLSMETPAKTEEIK 3719
+ + P+TP A T E P + + + TP + T + E PA T K
Sbjct: 581 KKLTPTTPEKLAP---TTPEKPAPTTPEELAPTTPEEPT-------PTTPEEPAPTTP-K 629
Query: 3720 LEKAETESCPGQEEPKLEEQNGSKVEGNAVACPVSSAQSPPHSAGAPAAKGDSGNELLKH 3779
T P PK E + + A P +A + P K + K
Sbjct: 630 AAAPNTPKEPAPTTPK--EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 687
Query: 3780 LLKNKKSSSLLNQKPEGSICSEDDCTKDNKLVEKQNPAEGLQTLGAQMQGGFGCGNQLPK 3839
K+ + ++P + C + T K P E T + P
Sbjct: 688 --APKELAPTTTKEPTSTTCDKPAPTTP-KGTAPTTPKEPAPTTPKE---------PAPT 735
Query: 3840 TDGGS--ETKKQRSKRTQR---TGEKAAPRSKKRKKDEEEKQAMYSSTDTFTHLKQQNNL 3894
T G+ T K+ + T + E A +K +K A + +T ++
Sbjct: 736 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP 795
Query: 3895 SNPPTPPASLPPTPPPMACQKMANGFATTEELAGKAGVLVSHEVTKTLGPKPFQLPFRPQ 3954
+ P P + P TPPP TT E++ + K+ +L P
Sbjct: 796 TTPKKPAPTTPETPPP-----------TTSEVSTPTTTKEPTTIHKSPDESTPELSAEP- 843
Query: 3955 DDLLARALAQGPKTVDVPASLPTPPHNNQEELRIQDHCGDRD---TPDS 4000
+AL PK VP + + +D +RD TP++
Sbjct: 844 ---TPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPET 889
Score = 40.0 bits (92), Expect = 0.057
Identities = 121/622 (19%), Positives = 173/622 (27%), Gaps = 93/622 (14%)
Query: 3512 PPSFVPDSPSIPVGSPNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAAPPVANSSLPCG 3571
P P +P P + + T + +P P P P + P
Sbjct: 306 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP-- 363
Query: 3572 QDSTITHGHSYPGSTQSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTKAPSTPHSDI-T 3630
+ T P +T+ + P + T KK AP+TP T
Sbjct: 364 --APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPT 421
Query: 3631 APPTPGISETTSTPAVSTPSE----LPQQADQESVEPVGPSTPNMAAGQLCTELENKLPN 3686
P P + TT PA +TP E P++ + + P+TP A E P
Sbjct: 422 TPKEP--APTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK 479
Query: 3687 SDFSQATPNQQTYANSEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVEG 3746
T + T + P +E T P PK K
Sbjct: 480 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE---PSPTTTKEPAPTTPKEPAPTTPKKPA 536
Query: 3747 NAVACPVSSAQSPPHSAGAPAAKGDSGNELLKHLLKNKKSSSLLNQKPEGSICSEDDCTK 3806
P + + P + PA KK + ++P + E T
Sbjct: 537 -----PTTPKEPAPTTPKEPAPT------------TTKKPAPTTPKEPAPTTPKETAPTT 579
Query: 3807 DNKLV----EKQNPAEGLQTLGAQMQGGFGCGNQLPKTDGGSETKKQRSKRTQRTGEKAA 3862
KL EK P + + +L T T + T + AA
Sbjct: 580 PKKLTPTTPEKLAPTTPEKPAPTTPE-------ELAPTTPEEPTPTTPEEPAPTTPKAAA 632
Query: 3863 PRSKKRKKDEEEKQAMYSSTDTFTHLKQQNNLSNPPTPPASLPPTPPPMACQKMANGFAT 3922
P + K K+ PT P PT P G A
Sbjct: 633 PNTPKEPAPTTPKEPA-------------------PTTPKEPAPTTPKETAPTTPKGTAP 673
Query: 3923 TEELAGKAGVLVSHEVTKTLGPKPFQLPFRPQDDLLARALAQG--PKTVDVPASLPTPPH 3980
T L A K L P + P D A +G P T PA PT P
Sbjct: 674 TT-LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA--PTTPK 730
Query: 3981 NNQEELRIQDHCGDRDTPDSFVPSSSPESVVGVEVSRYPDLSLVKEEPPEPVPSPIIPIL 4040
TP P++ E P +P P + P
Sbjct: 731 EPAPT-----------TPKGTAPTTLKEPA--------------PTTPKKPAPKELAPT- 764
Query: 4041 PSTAGKSSESRRNDIKTEPGTLYFASPFGPSPNGPRSGLISVAITLHPTAAENISSVVAA 4100
+T G +S + T P +P P+P P+ + T PT +E +
Sbjct: 765 -TTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTK 823
Query: 4101 FSDLLHVRIPNSYEVSSAPDVP 4122
+H S SA P
Sbjct: 824 EPTTIHKSPDESTPELSAEPTP 845
Score = 38.1 bits (87), Expect = 0.22
Identities = 81/458 (17%), Positives = 150/458 (32%), Gaps = 66/458 (14%)
Query: 3622 PSTPHSDITAPPTPGISETTSTPAVSTPSELPQQADQESVEPVGPSTPNMAAGQLCTELE 3681
P++P S APP G S+T + +P ++ ++ +E + + +E +
Sbjct: 69 PTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIE-----SEEITEEHSVSENQ 123
Query: 3682 NKLPNSDFSQATPNQQTYANSEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNG 3741
+S S ++ + +S+ + E K + +K T+ P + P ++E G
Sbjct: 124 ESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEA-G 182
Query: 3742 SKVEGNAVACPVSSAQSPPHSAGAPAAKGDSGNELLKHLLKNKKSSSLLNQKPEGSICSE 3801
S ++ + H+ + + K + + P S+
Sbjct: 183 SGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPI----------------NPRPSLPPN 226
Query: 3802 DDCTKDNKL-VEKQNPAEGLQTLGAQMQGGFGCGNQLPKTDGGSETKKQRSKRT-QRTGE 3859
D +K+ L V K+ E +T N+ TDG +T + ++ ++T
Sbjct: 227 SDTSKETSLTVNKETTVETKETTTT---------NKQTSTDGKEKTTSAKETQSIEKTSA 277
Query: 3860 K-AAPRSKKRKKDEEEKQAMYSSTDTFTHLKQQNNLSNPPTPPASLPPTPPPMACQKMAN 3918
K AP SK K + + T ++ + P P ++ P P P +
Sbjct: 278 KDLAPTSKVLAKPTPKAETTTKGPALTT--PKEPTPTTPKEPASTTPKEPTPTTIKSAPT 335
Query: 3919 GFATTEELAGKAGVLVSHEVTKTLGPKPFQLPFRPQDDLLARALAQGPKTVDVPASLPTP 3978
K+ E T +P P P++ P T S PT
Sbjct: 336 TPKEPAPTTTKSAPTTPKEPAPTTTKEP--APTTPKEPAPTTTKEPAPTTT---KSAPTT 390
Query: 3979 PHNNQEELRIQDHCGDRDTPDSFVPSSSPESVVGVEVSRYPDLSLVKEEPPEPVPSPIIP 4038
P TP P++ E P EP P+
Sbjct: 391 PKEPAP-----------TTPKKPAPTTPKEP--------------APTTPKEPTPTTPKE 425
Query: 4039 ILPSTAGKSSESRRNDIKTEPGTLYFASPFGPSPNGPR 4076
P+T + + + T P +P P+P P+
Sbjct: 426 PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK 463
Score = 34.7 bits (78), Expect = 2.4
Identities = 60/307 (19%), Positives = 99/307 (32%), Gaps = 34/307 (11%)
Query: 1794 LVQSGSDTPSSGIQSPLTPQPGNGNMS-----PAQSFHKELFTKQP----PSTPTSTSSD 1844
L + TP L P G S PA + KE P P+TP +
Sbjct: 745 LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA-- 802
Query: 1845 DVFVKPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPP-----SPMDPYA 1899
P P PP + + ++ T+ SP +P S P SP +P
Sbjct: 803 -----PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV 857
Query: 1900 KMVGTPRPPPVGHSFSRRNSAAPVE-NCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTT 1958
TP + + ++ + TP ++ + P ET +++TT
Sbjct: 858 PTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTT 917
Query: 1959 NNDPYAKPPDTPRPVMT----------DQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFT 2008
TP + T K++ + E+TAK P T+ T
Sbjct: 918 QVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAK-PKDRATNSKAT 976
Query: 2009 KPSPRADVFQRQRIPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLS 2068
P P+ + + P S +P P P M +P +++A + +
Sbjct: 977 TPKPQKPT-KAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTT 1035
Query: 2069 VDPYERP 2075
P + P
Sbjct: 1036 TRPNQTP 1042
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 91.3 bits (225), Expect = 2e-17
Identities = 137/635 (21%), Positives = 210/635 (33%), Gaps = 90/635 (14%)
Query: 1768 EATQKLEQVKNEQQQQQQQQFGSQHLLVQSGSD-TPSSGIQSPLTPQPGNGNMSPAQSFH 1826
E T +Q + +++ +Q + S D P+S + + TP+ PA +
Sbjct: 288 ETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTP 347
Query: 1827 KE---LFTKQPPST------PTSTSSDDVFVKPQAP---------PPPPAPSRI----PI 1864
KE K+P ST PT+ S K AP P PAP+ P
Sbjct: 348 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 407
Query: 1865 QDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNSAAPVE 1924
T++ P+P + + P+P P TP+ P + + P
Sbjct: 408 TPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEP----APTTPKEPTPTT 463
Query: 1925 NCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTDQFPKSLGL 1984
P + P TT P+P + TT +P P P P T + +
Sbjct: 464 PKEPAPTTKEPA---PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK 520
Query: 1985 SRSPVVSEQ---TAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLLT----PAPLD 2037
+P ++ T K P T T P + ++ P + P T PAP
Sbjct: 521 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT 580
Query: 2038 SGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQP 2097
TP +P P++ + + P E TP+ + P
Sbjct: 581 PKEPAPTTPKEPAPTTTKK-PAPTTPKEPAPTTPKETAPTTPKKL------TPTTPEKLA 633
Query: 2098 PLTPH---PAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPR---------PVVDSY 2145
P TP P E A + P T P P + P TP+ P +
Sbjct: 634 PTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTP 693
Query: 2146 SQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTP-----RPSTQTDLFVTPVTNQRHS 2200
+ + T T P + P GT T +P P+ P P+T + T +
Sbjct: 694 KEPAPTTPKETAP-TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 752
Query: 2201 DPYAHPPGTPR-PGISVPYSQPPATPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRGP 2259
P P TP+ P + P P TP+ + T P ++ L +GP
Sbjct: 753 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKE--LAPTTTKGP 810
Query: 2260 A-----LPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQSDSFG 2314
P P P +T TP+ P +P+ + P +P TP +
Sbjct: 811 TSTTSDKPAP-TTPKETAPTTPKEP-----------APTTPKKPAPTTPETPPPTTSEVS 858
Query: 2315 TSQTA------HDVADQPRP--GSEGSFCASSNSP 2341
T T H D+ P +E + A NSP
Sbjct: 859 TPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP 893
Score = 48.5 bits (114), Expect = 2e-04
Identities = 110/580 (18%), Positives = 183/580 (31%), Gaps = 70/580 (12%)
Query: 3518 DSPSIPVGSPNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAAPPVAN-SSLPCGQDSTI 3576
D+ V +P+ S+ + + S P+ P P+LP + +SL +++T+
Sbjct: 227 DNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR--PSLPPNSDTSKETSLTVNKETTV 284
Query: 3577 THGHSYPGSTQSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTKAPSTPHSDITAPPTPG 3636
+ + Q+ GK+K T K+ +++ P S + A PTP
Sbjct: 285 ETKETTTTNKQT----------STDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPK 334
Query: 3637 ISETTSTPAVSTPSELPQQADQESVEPVGPSTPNMAAGQLCTELENKLPNSDFSQATPNQ 3696
TT PA++TP E P+TP A T E + TP +
Sbjct: 335 AETTTKGPALTTPKE------------PTPTTPKEPAS--TTPKEPTPTTIKSAPTTPKE 380
Query: 3697 QTYANSEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVEGNAVACPVSSA 3756
++ + + PA T K + P + P ++ +A P A
Sbjct: 381 PAPTTTKSAPTTPKEPAPT----TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA 436
Query: 3757 QSPPHSAGAPAAKGDSGNELLKHLLKNKKSSSLLNQKPEGSICSEDDCTKDNKLVEKQNP 3816
+ P K + + K + ++P + E T K P
Sbjct: 437 PTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKK-PAPTTP 495
Query: 3817 AEGLQTLGAQMQGGFGCGNQLPKTDGGSETKKQRSKRTQRTGEKAAPRSKKRKKDEEEKQ 3876
E T + P E K T K+AP + K K
Sbjct: 496 KEPAPTTPKE-----------PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKS 544
Query: 3877 AMYSSTDTFTHLKQQNNLSNPPTPPASLPPTPPPMACQKMANGFATTEELAGKAGVLVSH 3936
A + + ++ + P P + P P P ++ A T +E A
Sbjct: 545 APTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP--TTPKEPA--------- 593
Query: 3937 EVTKTLGPKPF----QLPFRPQDDLLARALAQGPKTVD--VPASLPTPPHNNQEELRIQD 3990
T T P P P P++ P T + P + P EEL
Sbjct: 594 -PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA--- 649
Query: 3991 HCGDRDTPDSFVPSSSPESVVGVEVSRYPDLSLVKEEPPEPVPSPIIPILPSTAGKSSES 4050
TP+ P++ E + P+ P+P P P+ +
Sbjct: 650 ----PTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA 705
Query: 4051 RRNDIKTEPGTLYFASPFGPSPNGPRSGLISVAITLHPTA 4090
T P TL +P P P+ ++ T PT+
Sbjct: 706 PTTPKGTAPTTLKEPAPTTPKKPAPKE--LAPTTTKEPTS 743
Score = 40.4 bits (93), Expect = 0.044
Identities = 96/469 (20%), Positives = 153/469 (32%), Gaps = 55/469 (11%)
Query: 3547 SPVRPSFTPALPAAPPVANSSLPCGQDST-ITHGHSYPGSTQSLIQLYSDIIPEEKGKKK 3605
+P P+ T +P P S T P +T+S + P +
Sbjct: 502 TPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPA 561
Query: 3606 RTRKKKRDDDAESTKAPSTPHSDITAPPTPGISETTSTPAVSTPSE----LPQQADQESV 3661
T K+ AP+TP P TT PA +TP E P++ +
Sbjct: 562 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 621
Query: 3662 EPVGPSTPNMAAGQLCTELENKLPNS--DFSQATPNQQTYANSEVDKLSMETPAKTEEIK 3719
+ + P+TP A T E P + + + TP + T + E PA T K
Sbjct: 622 KKLTPTTPEKLAP---TTPEKPAPTTPEELAPTTPEEPT-------PTTPEEPAPTTP-K 670
Query: 3720 LEKAETESCPGQEEPKLEEQNGSKVEGNAVACPVSSAQSPPHSAGAPAAKGDSGNELLKH 3779
T P PK E + + A P +A + P K + K
Sbjct: 671 AAAPNTPKEPAPTTPK--EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP 728
Query: 3780 LLKNKKSSSLLNQKPEGSICSEDDCTKDNKLVEKQNPAEGLQTLGAQMQGGFGCGNQLPK 3839
K+ + ++P + C + T K P E T + P
Sbjct: 729 --APKELAPTTTKEPTSTTCDKPAPTTP-KGTAPTTPKEPAPTTPKE---------PAPT 776
Query: 3840 TDGGS--ETKKQRSKRTQR---TGEKAAPRSKKRKKDEEEKQAMYSSTDTFTHLKQQNNL 3894
T G+ T K+ + T + E A +K +K A + +T ++
Sbjct: 777 TPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP 836
Query: 3895 SNPPTPPASLPPTPPPMACQKMANGFATTEELAGKAGVLVSHEVTKTLGPKPFQLPFRPQ 3954
+ P P + P TPPP TT E++ + K+ +L P
Sbjct: 837 TTPKKPAPTTPETPPP-----------TTSEVSTPTTTKEPTTIHKSPDESTPELSAEP- 884
Query: 3955 DDLLARALAQGPKTVDVPASLPTPPHNNQEELRIQDHCGDRD---TPDS 4000
+AL PK VP + + +D +RD TP++
Sbjct: 885 ---TPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPET 930
Score = 40.0 bits (92), Expect = 0.057
Identities = 121/622 (19%), Positives = 173/622 (27%), Gaps = 93/622 (14%)
Query: 3512 PPSFVPDSPSIPVGSPNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAAPPVANSSLPCG 3571
P P +P P + + T + +P P P P + P
Sbjct: 347 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP-- 404
Query: 3572 QDSTITHGHSYPGSTQSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTKAPSTPHSDI-T 3630
+ T P +T+ + P + T KK AP+TP T
Sbjct: 405 --APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPT 462
Query: 3631 APPTPGISETTSTPAVSTPSE----LPQQADQESVEPVGPSTPNMAAGQLCTELENKLPN 3686
P P + TT PA +TP E P++ + + P+TP A E P
Sbjct: 463 TPKEP--APTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPK 520
Query: 3687 SDFSQATPNQQTYANSEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVEG 3746
T + T + P +E T P PK K
Sbjct: 521 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE---PSPTTTKEPAPTTPKEPAPTTPKKPA 577
Query: 3747 NAVACPVSSAQSPPHSAGAPAAKGDSGNELLKHLLKNKKSSSLLNQKPEGSICSEDDCTK 3806
P + + P + PA KK + ++P + E T
Sbjct: 578 -----PTTPKEPAPTTPKEPAPT------------TTKKPAPTTPKEPAPTTPKETAPTT 620
Query: 3807 DNKLV----EKQNPAEGLQTLGAQMQGGFGCGNQLPKTDGGSETKKQRSKRTQRTGEKAA 3862
KL EK P + + +L T T + T + AA
Sbjct: 621 PKKLTPTTPEKLAPTTPEKPAPTTPE-------ELAPTTPEEPTPTTPEEPAPTTPKAAA 673
Query: 3863 PRSKKRKKDEEEKQAMYSSTDTFTHLKQQNNLSNPPTPPASLPPTPPPMACQKMANGFAT 3922
P + K K+ PT P PT P G A
Sbjct: 674 PNTPKEPAPTTPKEPA-------------------PTTPKEPAPTTPKETAPTTPKGTAP 714
Query: 3923 TEELAGKAGVLVSHEVTKTLGPKPFQLPFRPQDDLLARALAQG--PKTVDVPASLPTPPH 3980
T L A K L P + P D A +G P T PA PT P
Sbjct: 715 TT-LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA--PTTPK 771
Query: 3981 NNQEELRIQDHCGDRDTPDSFVPSSSPESVVGVEVSRYPDLSLVKEEPPEPVPSPIIPIL 4040
TP P++ E P +P P + P
Sbjct: 772 EPAPT-----------TPKGTAPTTLKEPA--------------PTTPKKPAPKELAPT- 805
Query: 4041 PSTAGKSSESRRNDIKTEPGTLYFASPFGPSPNGPRSGLISVAITLHPTAAENISSVVAA 4100
+T G +S + T P +P P+P P+ + T PT +E +
Sbjct: 806 -TTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTK 864
Query: 4101 FSDLLHVRIPNSYEVSSAPDVP 4122
+H S SA P
Sbjct: 865 EPTTIHKSPDESTPELSAEPTP 886
Score = 38.1 bits (87), Expect = 0.22
Identities = 81/458 (17%), Positives = 150/458 (32%), Gaps = 66/458 (14%)
Query: 3622 PSTPHSDITAPPTPGISETTSTPAVSTPSELPQQADQESVEPVGPSTPNMAAGQLCTELE 3681
P++P S APP G S+T + +P ++ ++ +E + + +E +
Sbjct: 110 PTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIE-----SEEITEEHSVSENQ 164
Query: 3682 NKLPNSDFSQATPNQQTYANSEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNG 3741
+S S ++ + +S+ + E K + +K T+ P + P ++E G
Sbjct: 165 ESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEA-G 223
Query: 3742 SKVEGNAVACPVSSAQSPPHSAGAPAAKGDSGNELLKHLLKNKKSSSLLNQKPEGSICSE 3801
S ++ + H+ + + K + + P S+
Sbjct: 224 SGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPI----------------NPRPSLPPN 267
Query: 3802 DDCTKDNKL-VEKQNPAEGLQTLGAQMQGGFGCGNQLPKTDGGSETKKQRSKRT-QRTGE 3859
D +K+ L V K+ E +T N+ TDG +T + ++ ++T
Sbjct: 268 SDTSKETSLTVNKETTVETKETTTT---------NKQTSTDGKEKTTSAKETQSIEKTSA 318
Query: 3860 K-AAPRSKKRKKDEEEKQAMYSSTDTFTHLKQQNNLSNPPTPPASLPPTPPPMACQKMAN 3918
K AP SK K + + T ++ + P P ++ P P P +
Sbjct: 319 KDLAPTSKVLAKPTPKAETTTKGPALTT--PKEPTPTTPKEPASTTPKEPTPTTIKSAPT 376
Query: 3919 GFATTEELAGKAGVLVSHEVTKTLGPKPFQLPFRPQDDLLARALAQGPKTVDVPASLPTP 3978
K+ E T +P P P++ P T S PT
Sbjct: 377 TPKEPAPTTTKSAPTTPKEPAPTTTKEP--APTTPKEPAPTTTKEPAPTTT---KSAPTT 431
Query: 3979 PHNNQEELRIQDHCGDRDTPDSFVPSSSPESVVGVEVSRYPDLSLVKEEPPEPVPSPIIP 4038
P TP P++ E P EP P+
Sbjct: 432 PKEPAP-----------TTPKKPAPTTPKEP--------------APTTPKEPTPTTPKE 466
Query: 4039 ILPSTAGKSSESRRNDIKTEPGTLYFASPFGPSPNGPR 4076
P+T + + + T P +P P+P P+
Sbjct: 467 PAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPK 504
Score = 34.7 bits (78), Expect = 2.4
Identities = 60/307 (19%), Positives = 99/307 (32%), Gaps = 34/307 (11%)
Query: 1794 LVQSGSDTPSSGIQSPLTPQPGNGNMS-----PAQSFHKELFTKQP----PSTPTSTSSD 1844
L + TP L P G S PA + KE P P+TP +
Sbjct: 786 LKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPA-- 843
Query: 1845 DVFVKPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPP-----SPMDPYA 1899
P P PP + + ++ T+ SP +P S P SP +P
Sbjct: 844 -----PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGV 898
Query: 1900 KMVGTPRPPPVGHSFSRRNSAAPVE-NCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTT 1958
TP + + ++ + TP ++ + P ET +++TT
Sbjct: 899 PTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTT 958
Query: 1959 NNDPYAKPPDTPRPVMT----------DQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFT 2008
TP + T K++ + E+TAK P T+ T
Sbjct: 959 QVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAK-PKDRATNSKAT 1017
Query: 2009 KPSPRADVFQRQRIPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLS 2068
P P+ + + P S +P P P M +P +++A + +
Sbjct: 1018 TPKPQKPT-KAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTT 1076
Query: 2069 VDPYERP 2075
P + P
Sbjct: 1077 TRPNQTP 1083
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 90.9 bits (224), Expect = 3e-17
Identities = 150/613 (24%), Positives = 210/613 (34%), Gaps = 97/613 (15%)
Query: 1802 PSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKP-QAPPPPPAPS 1860
PS + +PL P + + P+ PP+TP S + + P QAPP
Sbjct: 333 PSPPLATPLPLAPPSPSAPPSLQT-----LPSPPATPPSQAPPSMTTPPMQAPPSLQTIP 387
Query: 1861 RIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSP--MDPYAKMVGTPRPPPVGHSFSRRN 1918
I + SL+ PPSP S + + SP ++ + +PR + R
Sbjct: 388 PIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRP 447
Query: 1919 SAAPVENC---TPLS-SVSRPLQMNETTANRP-------SPVRDLCSSSTTNNDPYAKPP 1967
++ P ++ PLS S PLQ + + A P P++ L SS ++ P A
Sbjct: 448 ASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQAL--SSLASHSPQAPLS 505
Query: 1968 DTPRPVMTDQF---PKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPD 2024
P + Q P SL + + + P A P P P
Sbjct: 506 SLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLA--------PPPLQTASAPLTTPH 557
Query: 2025 SYARPLLTPAPLDSGPGPFKTPMQPPPSS------QDPYGSVSQASRRLSVDPYERPALT 2078
P P PL + P P TP PSS Q P S + L P P T
Sbjct: 558 LETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLS-PLAT 616
Query: 2079 PRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTP 2138
P P + P PP P A PS P ++ Q P+S PP P
Sbjct: 617 PPP--QAPPXLALPPLQAPPSPPASPPLSPLATPSP--QAPNALAVHLLQAPFSPPPSPP 672
Query: 2139 RPVVDSYSQSSGTARSNTDPYSQPPG--------TPRPTTVDPYSQQ----PQTPRPSTQ 2186
S S + S T P PP P P P S PQ P P
Sbjct: 673 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA 732
Query: 2187 TDLFVTP-----------------VTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRI 2229
L V P V + P PP P P ++PP P +
Sbjct: 733 PPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL 792
Query: 2230 SEGFTRSSMTRPVLMPNQDPFLQAAQ-----------NRGPALPGPLVRPPDTCSQTP-- 2276
+ ++ + P P Q PF +A P L PL++ P + +P
Sbjct: 793 ATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL 852
Query: 2277 ----RPPGPGLSDTFS--RVSPSAA---RDPYDQSPMTPRSQSDSFGTSQTAHDVADQPR 2327
RPP PG + S R++ + A P +SP + S D G S +A ++ R
Sbjct: 853 QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 912
Query: 2328 ---PGSEGSFCAS 2337
G EG AS
Sbjct: 913 GYDSGPEGGAAAS 925
Score = 87.0 bits (214), Expect = 4e-16
Identities = 187/811 (23%), Positives = 279/811 (34%), Gaps = 125/811 (15%)
Query: 1878 SPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPP-VGHSFSRRNSAAPVENCTPLSSVSRPL 1936
+P +PG RPP G+PRPPP V + R AA PL+ + +
Sbjct: 16 TPAARAPGLLTPRPP----------GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGI 65
Query: 1937 --QMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQT 1994
+A R P R S+ T++ +P ++PP + R R+P ++ T
Sbjct: 66 GGATIPESAPRAGPTR---SAGTSSRNPASRPPASGRG------------ERAPP-AKNT 109
Query: 1995 AKGPIAA-GTSDHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDSG--PGPFKTPMQPPP 2051
+ GP+++ G + T+P P R ++ AR T AP S G + P P
Sbjct: 110 SPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP 169
Query: 2052 SSQDPYGSVSQASRRLSVD---PYERPALTPRP--------IDNFSHNQSNDPYSQPPLT 2100
+ P ++++ SR + P P+ PRP + + S + + +P P
Sbjct: 170 GTPSP--AMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP--SPAAR 225
Query: 2101 PHPAVNESFAHP-SRAFSQPGT-ISRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDP 2158
P+ P SR+ S T +S P P ++ GTPR ++ P
Sbjct: 226 RRPSAGGGLQRPASRSLSSSATPLSSPARSGPSAR--GTPRAPAHPSQPKPKGLQALRPP 283
Query: 2159 YSQPPGTPRPTTVDPYSQQP-QTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPR------ 2211
PP + P S P TP PS V P N P PP P
Sbjct: 284 QVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPL 343
Query: 2212 --PGISVPYS-----QPPATPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRGPAL--- 2261
P S P S PPATP + T M P + P P+L
Sbjct: 344 APPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAP 403
Query: 2262 PGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSA-----------ARDPYDQSPMTPRSQS 2310
P PL + + P + +F +SP A P D P+
Sbjct: 404 PSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSL 463
Query: 2311 DSFGTSQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPT-SGVTDTQN 2369
+ QT+ A P + S + S Q S + P+ T S +
Sbjct: 464 PASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSL 523
Query: 2370 TVNMAQADTEKLRQRQKLREIILQQQQQKKIAGRQEKGSQDSPAVPHPGPLQHWQPENVN 2429
A T L L LQ E +P P P PLQ P +
Sbjct: 524 QTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLE-----TPPCPAPCPLQ--APPS-- 574
Query: 2430 QAFTRPPPPYPGNIRSPVAPPLGPRYAVFPKDQRGPYPPDVASMGMRPHGFRFGFPGGSH 2489
T PPP P +I +P PP P P Q P PP ++ + P
Sbjct: 575 -PLTTPPPETPSSIATP--PPQAPPALASPPLQGLPSPP-LSPLATPPP------QAPPX 624
Query: 2490 GTMPSQERFLVPPQQIQGSGV---SPQLRRSVSVDMPRPLNNSQMNNPVGLPQHFSPQSL 2546
+P + PP S + SPQ +++V + + + + PV P FSP +
Sbjct: 625 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP--FSPPAS 682
Query: 2547 PVQQHNILGQAYIELRHRAPDGRQRLPFSAPPGSVVEASSNLRHGNFIPRPDFPGPRHTD 2606
P + + AP ++P S P + S+ P P+
Sbjct: 683 PPVSPSATPPSQAPPSLAAPP--LQVPPSPPASPPMSPSAT------------PPPQAPP 728
Query: 2607 PMRRPPQGLPNQLPVHPDLE-------QVPP 2630
P+ PP +P P P + +VPP
Sbjct: 729 PLAAPPLQVPPSPPASPPMSPSATPPPRVPP 759
Score = 86.7 bits (213), Expect = 5e-16
Identities = 132/551 (23%), Positives = 197/551 (35%), Gaps = 86/551 (15%)
Query: 1799 SDTPSSGIQSPLTPQ--PGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAPPPP 1856
S G+Q+ PQ P + +PA + P +TP+ + + V P
Sbjct: 270 SQPKPKGLQALRPPQVTPPRKDAAPALG----PLSSSPLATPSPSGTKARPVPPPDNAAT 325
Query: 1857 PAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPP------- 1909
P P+ +P L+ PPSP +P S + P P P ++ + PP
Sbjct: 326 PLPATLPPSPPLATPLPLAPPSPS--APPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSL 383
Query: 1910 -------VGHSFSRRNSAAP-----VENCTPLSSVSRPLQMNETTANRPSPVRDLCSSST 1957
V HS + + AP + + +S+ P + SP R +S T
Sbjct: 384 QTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSP-RQTQASLT 442
Query: 1958 TNNDPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVF 2017
+ + P + PPD+P L L SP + QT+ P + S T +A
Sbjct: 443 SPSRPASTPPDSP------PLQAPLSLPASPPL--QTSLSPAVSPLSSPLTIHPLQALSS 494
Query: 2018 QRQRIPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYER-PA 2076
P + L+ P PL++ +Q PP+S L+ P E P+
Sbjct: 495 LASHSPQAPLSSLIMP-PLETQSSLAPPSLQTPPAS-------------LTTPPLENLPS 540
Query: 2077 LTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPG 2136
L P P+ S + P+ + P P P P +A P T P + + PP
Sbjct: 541 LAPPPLQTASAPLTT-PHLETPPCPAPC-------PLQAPPSPLTTPPPETPSSIATPPP 592
Query: 2137 TPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTPVTN 2196
P + S G P + PP P P Q P +P S TP
Sbjct: 593 QAPPALAS-PPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQ 651
Query: 2197 QRHS-------DPYAHPPGTPRPGISVPYSQPPATPRPRISEGFTRSSMTRPVL------ 2243
++ P++ PP P + P+S PPA+ P +S T S P L
Sbjct: 652 APNALAVHLLQAPFSPPPSPP---VQAPFS-PPAS--PPVSPSATPPSQAPPSLAAPPLQ 705
Query: 2244 ---MPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFS---RVSPSAARD 2297
P P + + P P PL PP +P P P +S + + RV P A
Sbjct: 706 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP-PASPPMSPSATPPPRVPPLLAAP 764
Query: 2298 PYDQSPMTPRS 2308
P P P S
Sbjct: 765 PLQVPPSPPAS 775
Score = 71.6 bits (174), Expect = 2e-11
Identities = 115/502 (22%), Positives = 161/502 (32%), Gaps = 48/502 (9%)
Query: 1794 LVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAP 1853
L+ +T SS L P + P ++ P T ++ + P P
Sbjct: 507 LIMPPLETQSSLAPPSLQTPPASLTTPPLENLPS--LAPPPLQTASAPLTTPHLETPPCP 564
Query: 1854 PP-----PPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPP 1908
P PP+P P ++ S T P +P + P P+ P A P+ P
Sbjct: 565 APCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLA--TPPPQAP 622
Query: 1909 PVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPD 1968
P A P P S PL T PSP + P++ PP
Sbjct: 623 PX--------LALPPLQAPPSPPASPPLSPLAT----PSPQAPNALAVHLLQAPFSPPPS 670
Query: 1969 TPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYAR 2028
P + F SP + + P A P + P A
Sbjct: 671 PP---VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 727
Query: 2029 PLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHN 2088
P L PL P P +P P ++ P A+ L V P +L P+
Sbjct: 728 PPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAK-PPP 786
Query: 2089 QSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQS 2148
Q+ + PPL P+ SF P +A P S P S P + PP PV+ +
Sbjct: 787 QAPPALATPPLQALPSPPASF--PGQAPFSPSA-SLPMS--PLATPPPQAPPVLAA---- 837
Query: 2149 SGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPSTQTD-LFVTPVTNQRHSDPYAHPP 2207
P Q P +P + ++P TP P T +T P + P
Sbjct: 838 ---------PLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 888
Query: 2208 GTPRPGISVPYSQPPATPRPRISEGFTRSSMTRPVLMPNQDPFLQA----AQNRGPALPG 2263
+ G + AT P G+ P D L A A +RGPA P
Sbjct: 889 SSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPL 948
Query: 2264 PLVRPPDTCSQTPRPPGPGLSD 2285
P P GPG +D
Sbjct: 949 AFRGAPGAPLPWPPATGPGSAD 970
Score = 63.9 bits (154), Expect = 4e-09
Identities = 92/391 (23%), Positives = 129/391 (32%), Gaps = 65/391 (16%)
Query: 1792 HLLVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQ 1851
HLL S PS +Q+P +P P + +SP+ + P P S ++ + V P
Sbjct: 659 HLLQAPFSPPPSPPVQAPFSP-PASPPVSPSAT--------PPSQAPPSLAAPPLQVPPS 709
Query: 1852 APPPPP-APSRIPIQDS---LSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRP 1907
P PP +PS P + L+ PPSP P S ++ PP PR
Sbjct: 710 PPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPP------------PRV 757
Query: 1908 PPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPP 1967
PP+ AAP P S P+ + P + P + P
Sbjct: 758 PPL--------LAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPG 809
Query: 1968 DTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYA 2027
P F S L SP+ + P+ A P + Q R P
Sbjct: 810 QAP-------FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPP--- 859
Query: 2028 RPLLTPAPLDSGPGPFKT----PMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPID 2083
TP P S GP T P PPP S+ P ++S TP +
Sbjct: 860 ----TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPD---LAGHSSSATSTPEELR 912
Query: 2084 NFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVD 2143
+ + PP P + HP+ A+S+ P + PG P P
Sbjct: 913 GYDSGPEGGAAASPP----PDAELAACHPA-AWSR-----GPAPPLAFRGAPGAPLPWPP 962
Query: 2144 SYSQSSGTARSNTDPYSQP-PGTPRPTTVDP 2173
+ S P TP P +DP
Sbjct: 963 ATGPGSADGLCTIYETEGPESATPAPGALDP 993
Score = 53.1 bits (126), Expect = 7e-06
Identities = 33/109 (30%), Positives = 49/109 (44%), Gaps = 22/109 (20%)
Query: 3276 APPTMMPSVQP-QPPLIPGATPPTMSQPTFPMVPQQLQHQQHTTVISGHTSPVRMPSLPG 3334
+PP P P PP+ P ATPP+ + P+ P Q+ P P+ P
Sbjct: 670 SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV--------------PPSPPASPP 715
Query: 3335 WQPNSAPAHLPLNPPRIQPPIAQLPIKTCTPAPGTVSNANPQSGPPPRV 3383
P++ P PP+ PP+A P++ P+P +P + PPPRV
Sbjct: 716 MSPSATP------PPQAPPPLAAPPLQV-PPSPPASPPMSPSATPPPRV 757
Score = 51.6 bits (122), Expect = 2e-05
Identities = 40/126 (31%), Positives = 52/126 (41%), Gaps = 17/126 (13%)
Query: 3276 APPTMMPSVQP-QPPLIPGATPPTMSQPTFPMVPQQLQHQQHTT--VISGHTSPVRMPSL 3332
APP +P P PP+ P ATPP + P P Q+ + + T P R+P L
Sbjct: 701 APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPL 760
Query: 3333 ----PGWQPNSAPAHLPLNPPRIQPPIAQLPIKTCTPAPGTVSNANPQSGPPPRVEFDDN 3388
P P S PA LP++P PP AP ++ Q+ P P F
Sbjct: 761 LAAPPLQVPPSPPASLPMSPLAKPPP----------QAPPALATPPLQALPSPPASFPGQ 810
Query: 3389 NPFSES 3394
PFS S
Sbjct: 811 APFSPS 816
Score = 45.8 bits (107), Expect = 0.001
Identities = 89/420 (21%), Positives = 134/420 (31%), Gaps = 60/420 (14%)
Query: 2253 AAQNRGPALPGPLV-RPPDTCSQTPRPPGPGLSDTFSRVSPSAAR-----DPYDQSPMTP 2306
AA+ PG L RPP + PRPP P V+P+A R + P+
Sbjct: 13 AARTPAARAPGLLTPRPPGS----PRPPPP--------VTPAALRVLGAAGAVGRKPLAE 60
Query: 2307 RSQSDSFGTSQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQL-PGPVPTSG-V 2364
R+ T + A R S +S P +G++ PGPV + G
Sbjct: 61 RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA 120
Query: 2365 TDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKKI-AGRQEKGSQDSPAVPHPGPLQHW 2423
+ T + Q + R + ++ + AG + S +P P P +
Sbjct: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 180
Query: 2424 QPENVNQAFTRPPPPYPGNIRSPVAPPLGPRYAVFPKDQRGPYPPDVA------------ 2471
+ RP P P P GPR +V + P A
Sbjct: 181 RAAGTEVGLPRPAPS-----ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ 235
Query: 2472 ---SMGMRPHGFRFGFPGGSHGTMPSQERFLVPPQQIQGSGVSPQLRRSVSVDMPR---- 2524
S + P S + R P Q + G+ Q R V PR
Sbjct: 236 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGL--QALRPPQVTPPRKDAA 293
Query: 2525 PLNNSQMNNPVGLPQHFSPQSLPVQQHNILGQAYIELRHRAPDGRQRLPFSAPPGSVVEA 2584
P ++P+ P ++ PV + +P LP + P S +
Sbjct: 294 PALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPS 353
Query: 2585 SSNLRHGNFIPRPDFPGPRHTDPMRRPPQGLPNQLPVHPDLEQVPPSQQEQGHSVHSSSM 2644
L P P T P + PP + P L+ +PP Q HS+ S S+
Sbjct: 354 LQTL-----------PSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVP--HSLTSPSL 400
Score = 44.3 bits (103), Expect = 0.003
Identities = 38/111 (34%), Positives = 48/111 (43%), Gaps = 13/111 (11%)
Query: 3276 APPTMM-PSVQ--PQPPLIPGATPPTMSQPTFPMVPQQLQHQQHTTVISGHTSPVRMPSL 3332
APP + P +Q P PPL P ATPP + P + P Q + S SP+ PS
Sbjct: 594 APPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQ---APPSPPASPPLSPLATPSP 650
Query: 3333 PGWQPNSAPAHL---PLNPPRIQPPIAQLPIKTCTPAPGTVSNANPQSGPP 3380
PN+ HL P +PP PP+ Q P P + S P PP
Sbjct: 651 QA--PNALAVHLLQAPFSPPP-SPPV-QAPFSPPASPPVSPSATPPSQAPP 697
Score = 42.4 bits (98), Expect = 0.012
Identities = 29/109 (26%), Positives = 47/109 (43%), Gaps = 14/109 (12%)
Query: 3274 AMAPPTMMPSVQPQPPLIPGATPPTMSQPTFPMVPQQLQHQQHTTVISGHTSPVRMPSLP 3333
+ APP++ PP P + P + S P P L P+++P P
Sbjct: 693 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA-----------APPLQVPPSP 741
Query: 3334 GWQPNSAPAHLPLNPPRIQPPIAQLPIKTCTPAPGTVSNANPQSGPPPR 3382
P +P+ P PPR+ P +A P++ P+P +P + PPP+
Sbjct: 742 PASPPMSPSATP--PPRVPPLLAAPPLQV-PPSPPASLPMSPLAKPPPQ 787
Score = 42.4 bits (98), Expect = 0.012
Identities = 35/131 (26%), Positives = 46/131 (35%), Gaps = 29/131 (22%)
Query: 3276 APPTMMPSVQP-QPPLIPGATPPTMSQPTFPMVPQQLQHQQHTTVISGHTSPVRMP---- 3330
APP +P P PP+ P ATPP P P Q+ ++ SP+ P
Sbjct: 732 APPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASL---PMSPLAKPPPQA 788
Query: 3331 -----------------SLPGWQPNSAPAHLPLN----PPRIQPPIAQLPIKTCTPAPGT 3369
S PG P S A LP++ PP PP+ P+ P+P
Sbjct: 789 PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA 848
Query: 3370 VSNANPQSGPP 3380
PP
Sbjct: 849 SPTLQAPRRPP 859
Score = 38.5 bits (88), Expect = 0.17
Identities = 30/117 (25%), Positives = 50/117 (42%), Gaps = 11/117 (9%)
Query: 3270 QQQCAMAPPTMM--PSVQPQPPL--IPGATPPTMSQPTFPMVPQQLQHQQHTTVISGHTS 3325
+ Q ++APP++ P+ PPL +P PP + + P+ L+ T
Sbjct: 513 ETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLE-----TPPCPAPC 567
Query: 3326 PVRMPSLP-GWQPNSAPAHLPLNPPRIQPPIAQLPIKTCTPAPGTVSNANPQSGPPP 3381
P++ P P P P+ + PP+ P +A P++ P+P A P PP
Sbjct: 568 PLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQG-LPSPPLSPLATPPPQAPP 623
Score = 35.0 bits (79), Expect = 1.8
Identities = 76/338 (22%), Positives = 102/338 (30%), Gaps = 55/338 (16%)
Query: 3894 LSNPPTPPASLPPTPPPMACQKMA----------------NGFATTEELAGKAGVLVSHE 3937
L P+PP S TPPP A +A + AT A A L H
Sbjct: 603 LQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNA--LAVHL 660
Query: 3938 VTKTLGP---KPFQLPFRPQDDLLARALAQGPKTVDVPASLPTPPHNNQEELRIQDHCGD 3994
+ P P Q PF P A P P SL PP
Sbjct: 661 LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS--QAPPSLAAPPLQVPPSPPASPPMSP 718
Query: 3995 RDTPDSFV---------------PSSSPESVVGVEVSRYPDLSL-----VKEEPPEPVP- 4033
TP P+S P S R P L V PP +P
Sbjct: 719 SATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPM 778
Query: 4034 SPIIPILPSTAGKSSESRRNDIKTEPGTLYFASPFGPSPNGPRSGLISVAITLHPTAAEN 4093
SP+ P + + + P + +PF PS + P S L + P A
Sbjct: 779 SPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP 838
Query: 4094 ISSVVAAFSDLLHVRIPNSYEVSSAPDVPSMGLVSSHRINPGLEYRQHLLLRGPPPGSAN 4153
+ V + ++ P + PD G + + PG PPP S +
Sbjct: 839 LLQVPPSPPASPTLQAPRR-PPTPGPDTSVSGPRLTLALAPG----------PPPPPSRS 887
Query: 4154 PPRLVSSYRLKQPNVPFPPTSNGLSGYKDSSHGIAESA 4191
P +S L + T L GY G A ++
Sbjct: 888 PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAAS 925
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 90.9 bits (224), Expect = 3e-17
Identities = 192/859 (22%), Positives = 283/859 (32%), Gaps = 201/859 (23%)
Query: 1764 QAKIEATQKLEQVKNEQQQQQQQQFGSQH--LLVQSGSDTPSSGIQSP--LTPQPGNGNM 1819
Q + + LEQV N + ++ +G++ V+ ++ P P L+ G +
Sbjct: 164 QHRAKVLPPLEQVWNLLHLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALSGPSGEEGL 223
Query: 1820 SPAQSFHKELFTKQ---PPSTPTSTSSDDVFVKPQAPPPPPAPSRIPIQDSLSQAQTSQP 1876
SP + ++Q PP P P PPPPP P P L+ + Q
Sbjct: 224 SPGGKRRRGCNSEQTGLPPGLPLPPP-------PLPPPPPPPPPPPPPLPGLATSPPFQL 276
Query: 1877 PSPQVFS--------PGSSNSRPPSPMD---------PYAKMVGTPRPPPVGHSF----- 1914
P ++S P S PP + PY T PP GH
Sbjct: 277 TKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPAYTAHPP--GHRLVPAAP 334
Query: 1915 ---SRRNSAAPVENCTPLSSVSRP--LQMNETTANRPSPVRDLCSSSTTNNDPYA--KPP 1967
R A C P +RP + E+ R + ++TT PYA +PP
Sbjct: 335 PGPGPRPPGAESHGCLP---ATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPP 391
Query: 1968 DTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPS----------PRADVF 2017
P + S V G +DH+ P+ P A
Sbjct: 392 GLPGTTTSSSSSSSSNTGLRGVEPNPGIPG------ADHYQTPALEVSHHGRLGPSAHSS 445
Query: 2018 QRQRIPDSYARPLLTPAPLDSGPGPFKTP--MQPPPSSQDPYGSVSQASRRLSVDPYERP 2075
++ + A P L+ P S P P P ++PPP G +A+R
Sbjct: 446 RKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAARE--------- 496
Query: 2076 ALTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPP 2135
++ P PP PH E F P + GT QD ++ PP
Sbjct: 497 --DGEILEELFFGTEGPPRPAPPPLPH---REGFLGPPASRFSVGT------QDSHT-PP 544
Query: 2136 GTPRPVVDSYSQSSGT-ARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTPV 2194
P P S + +SG+ + S P S PP ++DP PRP P
Sbjct: 545 TPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDP------LPRP---------PS 589
Query: 2195 TNQRHSDPYAHPPGTPRPGISVPYSQPPATP---RPRISEGFTRSSMTRPVLMPNQDPFL 2251
Q DP P + + + PPA P S F R RP + + P +
Sbjct: 590 PAQNPQDP---------PLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEV 640
Query: 2252 QAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSR------VSPSAARDPYDQ---- 2301
PGP PP S+ P+P PG+ + +R P+ D +++
Sbjct: 641 G---------PGP---PPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEF 688
Query: 2302 --------SPMTPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGVS 2353
+ M +S Q H+ P+P + F AS SP F +
Sbjct: 689 KILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPF-ASLQSP-------FPTDT 740
Query: 2354 QLPGPVPTSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKKIAGRQEKGSQDSPA 2413
P VT T T A QE+ + PA
Sbjct: 741 APTTTAPAVAVTTTTTTTTTTTA--------------------------TQEEEKKPPPA 774
Query: 2414 VPHPGPLQHWQPENVNQAFTRPPPPYPGNIRSPVAPPL-GPRYAV-------------FP 2459
+P P PL + P + Q PPPP P ++ +A L G +Y P
Sbjct: 775 LPPPPPLAKFPPPSQPQP-PPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLP 833
Query: 2460 KDQRGPYPPDVASMGMRPHGFRFGFPGGSHGTMPSQERFLVPPQQIQGSGVSPQLRRSVS 2519
Q P PP A+ + P G + S +F G + RR+
Sbjct: 834 TTQYSPGPPSGAT-ALPPTSAAPSAQGSPQPSASSSSQFST------SGGPWARERRAGE 886
Query: 2520 VDMPRPLNNSQMNNPVGLP 2538
+P P+ +Q P+ LP
Sbjct: 887 EPVPGPMTPTQPPPPLSLP 905
Score = 68.2 bits (165), Expect = 2e-10
Identities = 160/737 (21%), Positives = 247/737 (33%), Gaps = 124/737 (16%)
Query: 1807 QSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAPPPPPAPSRIPIQD 1866
Q+P +G + P+ ++ F P +TP + P +PPPPP P +
Sbjct: 426 QTPALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPG----PSSPPPPPCPRLL---- 477
Query: 1867 SLSQAQTSQPPSPQVF--SPGSSNSRPPSPM--DPYAKMVGTPRP--PPVGHSFSRRNSA 1920
+PP P + P +R + + + G PRP PP+ H R
Sbjct: 478 --------RPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPH---REGFL 526
Query: 1921 APVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTDQF-P 1979
P P S S Q + T P+P SSS +N+ ++ P P +
Sbjct: 527 GP-----PASRFSVGTQDSHTPPTPPTPTT---SSSNSNSGSHSSSPAGPVSFPPPPYLA 578
Query: 1980 KSLG-LSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDS 2038
+S+ L R P ++ P+ T P+P + Q S+ RP +P P S
Sbjct: 579 RSIDPLPRPPSPAQNPQDPPLVPLTLA--LPPAPPSSC--HQNTSGSFRRPE-SPRPRVS 633
Query: 2039 GPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPP 2098
P + PPP G +S+A + + E PA PR D F D + +P
Sbjct: 634 FPKTPEVGPGPPP------GPLSKAPQPVPPGVGELPARGPRLFD-FPPTPLEDQFEEP- 685
Query: 2099 LTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDP 2158
+ + A+ + + +I + Q + P+ + ++
Sbjct: 686 -AEFKILPDGLANIMKMLDE--SIRKEEEQQQHEAGVAPQPPLKEPFASLQ--------- 733
Query: 2159 YSQPPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPY 2218
+P PT P + P +T T T T + P P P P
Sbjct: 734 ------SPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPP 787
Query: 2219 SQPPATPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRP 2278
SQP P P S S+ ++ Q + PGPL T +P P
Sbjct: 788 SQPQPPPPPPPSPASLLKSLAS--VLEGQKYCYRGTGAAVSTRPGPL----PTTQYSPGP 841
Query: 2279 PGPGLSDTFSRVSPSAARDPYDQSPMTPRSQSDSFGTS----QTAHDVADQPRPGSEGSF 2334
P + + P++A SP S S F TS ++P PG
Sbjct: 842 PSGA-----TALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPT 896
Query: 2335 CAS---SNSPMHSQGQQFSGVSQL---------------PGPVPTSGVTD--TQNTVNMA 2374
S P S+ + +S+ PV T+ D T+ + A
Sbjct: 897 QPPPPLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPA 956
Query: 2375 QADTE-----------KLRQRQKLREIILQQQQQKKIAGRQEKGSQDSPAVPHP------ 2417
QA E K RQ++ +E ++ K GR+ + + P
Sbjct: 957 QAKEEAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRR 1016
Query: 2418 --GPLQHWQPENVNQAFTRPPPPYPGNIRSPVAPPLGPRYAVFPKDQRGPYPPDVASMGM 2475
G L E + +RP + P AP P A P Q P PP + G
Sbjct: 1017 VLGNLDLQSEEIQGREKSRPDLGGASKAKPPTAP--APPSAPAPSAQ--PTPPSASVPGK 1072
Query: 2476 RPHGFRFGFPGGSHGTM 2492
+ G PG S M
Sbjct: 1073 KAREEAPGPPGVSRADM 1089
Score = 43.9 bits (102), Expect = 0.004
Identities = 72/308 (23%), Positives = 113/308 (36%), Gaps = 59/308 (19%)
Query: 1774 EQVKNEQQQQQQQQFGSQHLLVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQ 1833
E ++ E++QQQ + + Q P + +QSP +PA + T
Sbjct: 704 ESIRKEEEQQQHEA----GVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAV-----TTT 754
Query: 1834 PPSTPTSTSSDDVFVKPQAPPPPPAP-SRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPP 1892
+T T+T++ + KP PPP P ++ P +Q PP P PP
Sbjct: 755 TTTTTTTTATQEEEKKPPPALPPPPPLAKFP-----PPSQPQPPPPP-----------PP 798
Query: 1893 SPMDPYAKMVGTPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDL 1952
SP A ++ + G + R + A V S+ PL TT P P
Sbjct: 799 SP----ASLLKSLASVLEGQKYCYRGTGAAV------STRPGPL---PTTQYSPGPPSGA 845
Query: 1953 CSSSTTNNDPYAKPPDTPRPVMTDQFPKSLG-LSRSPVVSEQTAKGPIA----------- 2000
+ T+ P A+ P + QF S G +R E+ GP+
Sbjct: 846 TALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLP 905
Query: 2001 -AGTSDHFTKPSPRADVFQRQRIPDSY---ARPLLTPAPLDSGPGPFKTPMQPPPSSQDP 2056
A + + RA +R+ S A P+ T P DSG + PP +++
Sbjct: 906 PARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSG----TERLLPPAQAKEE 961
Query: 2057 YGSVSQAS 2064
G V+ S
Sbjct: 962 AGGVAAVS 969
Score = 35.0 bits (79), Expect = 1.8
Identities = 27/95 (28%), Positives = 36/95 (37%), Gaps = 8/95 (8%)
Query: 3896 NPPTPPA-----SLPPTPPPMACQKMANGFATTEELAGKAGVLVSHEVTKTLGPKPFQLP 3950
NP PP +LPP PP Q + F E + + EV P P
Sbjct: 593 NPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKA 652
Query: 3951 FRPQDDLLARALAQGPKTVDVPASLPTPPHNNQEE 3985
+P + A+GP+ D P PTP + EE
Sbjct: 653 PQPVPPGVGELPARGPRLFDFP---PTPLEDQFEE 684
Score = 33.5 bits (75), Expect = 5.3
Identities = 21/56 (37%), Positives = 23/56 (41%), Gaps = 4/56 (7%)
Query: 1854 PPPPAPSRIPIQDSLSQAQTSQPPSPQVFSP--GSSNSRPPSPMDPYAKMVGTPRP 1907
PP P P + A QPP P P GSS+ P P YA TPRP
Sbjct: 32 PPHPPPRSAWLPGGRCSASIGQPPLPAPLPPSHGSSSGHPSKPY--YAPGAPTPRP 85
>gi|205830432 D4, zinc and double PHD fingers family 1 isoform b [Homo
sapiens]
Length = 380
Score = 90.5 bits (223), Expect = 4e-17
Identities = 41/110 (37%), Positives = 58/110 (52%), Gaps = 14/110 (12%)
Query: 960 CVVC--GSFGQGAEGRLLACSQCGQCYHPYCV--SIKITKVVLSKGWRCLECTVCEACGK 1015
C C GS G L++C+ CG+ HP C+ ++ +T V + W+C+EC C CG
Sbjct: 257 CDFCLGGSKKTGCPEDLISCADCGRSGHPSCLQFTVNMTAAVRTYRWQCIECKSCSLCGT 316
Query: 1016 ATDPG----------RLLLCDDCDISYHTYCLDPPLQTVPKGGWKCKWCV 1055
+ + G +LL CDDCD YH YCL PP+ P+G W C C+
Sbjct: 317 SENDGASWAGLTPQDQLLFCDDCDRGYHMYCLSPPMAEPPEGSWSCHLCL 366
Score = 72.8 bits (177), Expect = 8e-12
Identities = 36/99 (36%), Positives = 44/99 (44%), Gaps = 16/99 (16%)
Query: 350 PGDLLDQFFCTTCGQHYHGMCLDIAVT---PLKRAGWQCPECKVCQNCKQSGEDS----- 401
P DL+ C CG+ H CL V ++ WQC ECK C C S D
Sbjct: 270 PEDLIS---CADCGRSGHPSCLQFTVNMTAAVRTYRWQCIECKSCSLCGTSENDGASWAG 326
Query: 402 -----KMLVCDTCDKGYHTFCLQPVMKSVPTNGWKCKNC 435
++L CD CD+GYH +CL P M P W C C
Sbjct: 327 LTPQDQLLFCDDCDRGYHMYCLSPPMAEPPEGSWSCHLC 365
Score = 41.6 bits (96), Expect = 0.020
Identities = 30/114 (26%), Positives = 44/114 (38%), Gaps = 14/114 (12%)
Query: 388 CKVCQN-CKQSGEDSKMLVCDTCDKGYHTFCLQPVMK---SVPTNGWKCKNCRICIECGT 443
C C K++G ++ C C + H CLQ + +V T W+C C+ C CGT
Sbjct: 257 CDFCLGGSKKTGCPEDLISCADCGRSGHPSCLQFTVNMTAAVRTYRWQCIECKSCSLCGT 316
Query: 444 --RSSSQW-----HHNCLICDNCYQQQDNLCPFCGKCYHPELQKDMLHCNMCKR 490
+ W L CD+C + C PE C++C R
Sbjct: 317 SENDGASWAGLTPQDQLLFCDDCDRGYHMYCLSPPMAEPPE---GSWSCHLCLR 367
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 89.7 bits (221), Expect = 6e-17
Identities = 154/611 (25%), Positives = 217/611 (35%), Gaps = 92/611 (15%)
Query: 1798 GSDTPSSGIQSPLTPQPGNGNMSPAQ----SFHKELFTKQPPSTPTSTSSDDVFVKPQAP 1853
G+ P S ++ T G + +PA S E ++P SS P
Sbjct: 67 GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 126
Query: 1854 PPPPAPS-RIPIQDSLSQAQTSQPPSPQVFSPGSS-NSRPPSPMDPYAKM---------- 1901
P RI ++++++ + ++ P S G+ ++ P+P P M
Sbjct: 127 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 186
Query: 1902 VGTPRPPPVGHSFS------RRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSS 1955
VG PRP P + S+A + T S +R RP+ R L SS
Sbjct: 187 VGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS-RSLSSS 245
Query: 1956 STTNNDPYAKPPD---TPRPVMTDQFPKSLGLS--RSPVVSEQTAKGPIAAG--TSDHFT 2008
+T + P P TPR PK GL R P V+ A G +S
Sbjct: 246 ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA 305
Query: 2009 KPSPRADVFQRQRIPDSYARP--------LLTPAPL----DSGPGPFKT----PMQPPPS 2052
PSP A Q Q P A P L TP PL S P +T P PP
Sbjct: 306 TPSPSA-ALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ 364
Query: 2053 SQDPYGSVS-QASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAH 2111
+ GS + QA+ P P TP P + P PP P A
Sbjct: 365 ATTSLGSPTLQATHSFLPSPPLSPLATPPP--QAPPALALPPLQAPPSPPASPPLSPLAT 422
Query: 2112 PSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTV 2171
PS P ++ Q P+S PP P + S A P + PP P+
Sbjct: 423 PSP--QAPNALAVHLLQAPFSPPPSPP-----VQAPFSPPASPPVSPSATPPSQAPPSLA 475
Query: 2172 DPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISE 2231
P Q P +P S TP P A PP P + ++PP P ++
Sbjct: 476 APPLQVPPSPPASPPMSPSATP-------PPQAPPPLAAPP---LQLAKPPPQAPPALAT 525
Query: 2232 GFTRSSMTRPVLMPNQDPFLQAAQ-----------NRGPALPGPLVRPPDTCSQTP---- 2276
++ + P P Q PF +A P L PL++ P + +P
Sbjct: 526 PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 585
Query: 2277 --RPPGPGLSDTFS--RVSPSAA---RDPYDQSPMTPRSQSDSFGTSQTAHDVADQPR-- 2327
RPP PG + S R++ + A P +SP + S D G S +A ++ R
Sbjct: 586 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 645
Query: 2328 -PGSEGSFCAS 2337
G EG AS
Sbjct: 646 DSGPEGGAAAS 656
Score = 77.8 bits (190), Expect = 2e-13
Identities = 129/506 (25%), Positives = 168/506 (33%), Gaps = 64/506 (12%)
Query: 1812 PQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAPPPPPAPSRIPIQDSLSQA 1871
P G G PA + L + P + + S P+AP P P +Q +L
Sbjct: 228 PSAGGGLQRPAS---RSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ-ALRPP 283
Query: 1872 QTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRP--PPVGHSFSRR-NSAAPVENCTP 1928
Q + P + G +S P + P A + P P HS S A P+ P
Sbjct: 284 QVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPP 343
Query: 1929 LSSVSRPLQ-MNETTANRPSPVRDLCSSST--TNNDPYAKPPDTPRPVMTDQFPKSLGLS 1985
S LQ + A PS S T + PP +P Q P +L L
Sbjct: 344 SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP 403
Query: 1986 RSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLL----TPAPLDSGPG 2041
P+ Q P A+ PSP+A P++ A LL +P P
Sbjct: 404 --PL---QAPPSPPASPPLSPLATPSPQA--------PNALAVHLLQAPFSPPPSPPVQA 450
Query: 2042 PFKTPMQPP--PSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPL 2099
PF P PP PS+ P SQA L+ P + P P P P
Sbjct: 451 PFSPPASPPVSPSATPP----SQAPPSLAAPPLQVPPSPPA-----------SPPMSPSA 495
Query: 2100 TPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPY 2159
TP P A P ++P + P P Q +P + S +A P
Sbjct: 496 TPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 555
Query: 2160 SQPPGTPRPTTVDPYSQQPQTP--RPSTQTDLFV-TPVTNQRHSDP---YAHPPGTPRPG 2213
+ PP P P Q P +P P+ Q TP + S P A PG P P
Sbjct: 556 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 615
Query: 2214 ISVPYS----------QPPATPRPRISEGFTRSSMTRPVLMPNQDPFLQA----AQNRGP 2259
P S AT P G+ P D L A A +RGP
Sbjct: 616 SRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP 675
Query: 2260 ALPGPLVRPPDTCSQTPRPPGPGLSD 2285
A P P P GPG +D
Sbjct: 676 APPLAFRGAPGAPLPWPPATGPGSAD 701
Score = 54.7 bits (130), Expect = 2e-06
Identities = 84/318 (26%), Positives = 111/318 (34%), Gaps = 53/318 (16%)
Query: 1792 HLLVQSGSDTPSSGIQSPLTPQ---PGNGNMSPAQSFHKELFT---KQPPSTPTSTS-SD 1844
HLL S PS +Q+P +P P + + +P L + PPS P S S
Sbjct: 434 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 493
Query: 1845 DVFVKPQAPPP---------------PPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNS 1889
PQAPPP PPA + P+Q PSP PG +
Sbjct: 494 SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQ---------ALPSPPASFPGQAPF 544
Query: 1890 RPPS--PMDPYAKMVGTPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPS 1947
P + PM P A P+ PPV AAP+ P S LQ P+
Sbjct: 545 SPSASLPMSPLA--TPPPQAPPV--------LAAPLLQVPPSPPASPTLQ---APRRPPT 591
Query: 1948 PVRDLCSSS---TTNNDPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTS 2004
P D S T P PP + P T P G S S + + +G +
Sbjct: 592 PGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 651
Query: 2005 DHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDSGPG-PFKTPMQPPPSSQDPYGSVSQA 2063
P P A++ P +++R P PG P P P S D ++ +
Sbjct: 652 GAAASPPPDAELAACH--PAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYET 709
Query: 2064 SRRLSVDPYERPALTPRP 2081
S P AL P P
Sbjct: 710 EGPESATP-APGALDPGP 726
Score = 50.4 bits (119), Expect = 4e-05
Identities = 35/115 (30%), Positives = 46/115 (40%), Gaps = 10/115 (8%)
Query: 3276 APPTMMPSVQP-QPPLIPGATPPTMSQPTFPMVPQQLQHQQHTTVISGHTSPVRM----- 3329
APP +P P PP+ P ATPP + P P QL + T P++
Sbjct: 476 APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPP 535
Query: 3330 PSLPGWQPNSAPAHLPLN----PPRIQPPIAQLPIKTCTPAPGTVSNANPQSGPP 3380
S PG P S A LP++ PP PP+ P+ P+P PP
Sbjct: 536 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPP 590
Score = 44.3 bits (103), Expect = 0.003
Identities = 37/116 (31%), Positives = 48/116 (41%), Gaps = 12/116 (10%)
Query: 3270 QQQCAMAPPTMMP--SVQPQPPLIPGATPPTMSQPTFPMVPQQLQHQQHTTVISGHTSPV 3327
Q ++ PT+ S P PPL P ATPP + P + P Q + S SP+
Sbjct: 364 QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQ---APPSPPASPPLSPL 420
Query: 3328 RMPSLPGWQPNSAPAHL---PLNPPRIQPPIAQLPIKTCTPAPGTVSNANPQSGPP 3380
PS PN+ HL P +PP PP+ Q P P + S P PP
Sbjct: 421 ATPSPQA--PNALAVHLLQAPFSPPP-SPPV-QAPFSPPASPPVSPSATPPSQAPP 472
Score = 43.9 bits (102), Expect = 0.004
Identities = 157/697 (22%), Positives = 214/697 (30%), Gaps = 158/697 (22%)
Query: 2021 RIPDSYARPLLTPAPLDSGPGPFKTPMQPPP---------SSQDPYGSVSQASRRLSVDP 2071
R P + A LLTP P PG +P PPP + G A R +
Sbjct: 15 RTPAARAPGLLTPRP----PG---SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG 67
Query: 2072 YERPALTPRPIDNFSHNQSN-DPYSQPPLTPH-----PAVNES---FAHPSRAF--SQPG 2120
P PR S S+ +P S+PP + PA N S + P RA ++PG
Sbjct: 68 ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG 127
Query: 2121 TIS----RPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQ 2176
+ R ++++ ++ T P +S+ +A + D PGTP P
Sbjct: 128 PLGQKGLRISAEETVARGKATEAP-----KRSALSAGARRDTSGPTPGTPSPAMA----- 177
Query: 2177 QPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFTRS 2236
R S G PRP S P PR +S +
Sbjct: 178 ---------------------RRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSA-SEH 215
Query: 2237 SMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAAR 2296
S T P A R P+ G L RP + P LS +R PSA
Sbjct: 216 STTEP----------SPAARRRPSAGGGLQRPASRSLSSSATP---LSSP-ARSGPSARG 261
Query: 2297 DPYDQSPMTPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLP 2356
P ++P P SQ G PR + + S+SP+ + + SQ P
Sbjct: 262 TP--RAPAHP-SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAP 318
Query: 2357 GPVPTSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKKIAG-RQEKGSQDSPAVP 2415
PT T +++ A L LQ Q S SP +
Sbjct: 319 ---PTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTL- 374
Query: 2416 HPGPLQHWQPENVNQAFTRPPPPYPGNIRSPVAPPLGPRYAVFPKDQRGPYPPDVASMGM 2475
+F PP P + +P PP P P Q P PP AS +
Sbjct: 375 -----------QATHSFLPSPPLSP--LATP--PPQAPPALALPPLQAPPSPP--ASPPL 417
Query: 2476 RPHGFRFGFPGGSHGTMPSQERFLVPPQQIQGSGVSPQLRRSVSVDMPRPLNNSQMNNPV 2535
P L P + ++ L ++ P P + + P
Sbjct: 418 SP---------------------LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 456
Query: 2536 GLPQHFSPQSLPVQQHNILGQAYIELRHRAPDGRQRLPFSAPPGSVVEASSNLRHGNFIP 2595
P SP + P Q AP P PP +
Sbjct: 457 SPP--VSPSATPPSQ--------------APPSLAAPPLQVPPSPPASPPMS-------- 492
Query: 2596 RPDFPGPRHTDPMRRPPQGLPNQLPVHPDLEQVPPSQ---------QEQGHSVHSSSMVM 2646
P P+ P+ PP L P P PP Q Q S+S+ M
Sbjct: 493 PSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM 552
Query: 2647 RTL--NHPLGGEFSEAPLSTSVPSETTSDNLQITTQP 2681
L P APL PS S LQ +P
Sbjct: 553 SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP 589
Score = 38.5 bits (88), Expect = 0.17
Identities = 71/303 (23%), Positives = 99/303 (32%), Gaps = 56/303 (18%)
Query: 3894 LSNPPTPPASLPPTPPPMACQKMANGFATTEELAGKAGVLVSHEVTKTLGP---KPFQLP 3950
L PP+PPAS P +P AT A A L H + P P Q P
Sbjct: 405 LQAPPSPPASPPLSP-----------LATPSPQAPNA--LAVHLLQAPFSPPPSPPVQAP 451
Query: 3951 FRPQDDLLARALAQGPKTVDVPASLPTPPHNNQEELRIQDHCGDRDTPDSFVPSSSPESV 4010
F P A P P SL PP ++ +P + P +P +
Sbjct: 452 FSPPASPPVSPSATPPS--QAPPSLAAPP----LQVPPSPPASPPMSPSATPPPQAPPPL 505
Query: 4011 VGVEVSRYPDLSLVKEEP--PEPVPSPIIPILPSTAGKSSESRRNDIKTEPGTLYFASPF 4068
P L L K P P + +P + LPS P + +PF
Sbjct: 506 AA------PPLQLAKPPPQAPPALATPPLQALPS---------------PPASFPGQAPF 544
Query: 4069 GPSPNGPRSGLISVAITLHPTAAENISSVVAAFSDLLHVRIPNSYEVSSAPDVPSMGLVS 4128
PS + P S L + P A + V + ++ P + PD G
Sbjct: 545 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR-PPTPGPDTSVSGPRL 603
Query: 4129 SHRINPGLEYRQHLLLRGPPPGSANPPRLVSSYRLKQPNVPFPPTSNGLSGYKDSSHGIA 4188
+ + PG PPP S +P +S L + T L GY G A
Sbjct: 604 TLALAPG----------PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGA 653
Query: 4189 ESA 4191
++
Sbjct: 654 AAS 656
>gi|197313748 SET domain containing 2 [Homo sapiens]
Length = 2564
Score = 89.4 bits (220), Expect = 8e-17
Identities = 45/149 (30%), Positives = 83/149 (55%), Gaps = 2/149 (1%)
Query: 4763 RKMKTEWKSNVYLARSRIQGLGLYAARDIEKHTMVIEYIGTIIRNEVANRKEKLY-ESQN 4821
R+ + + ++V + + +G GL AA+D+ +T V+EY G ++ ++ + K Y ++N
Sbjct: 1542 RRFQRKQHADVEVILTEKKGWGLRAAKDLPSNTFVLEYCGEVLDHKEFKARVKEYARNKN 1601
Query: 4822 RGVYMFRMDNDHVIDATLTGGPARYINHSCAPNCVAEVVTFERGHKIIISSSRRIQKGEE 4881
Y + ND +IDAT G +R++NHSC PNC + T ++ +++ + G E
Sbjct: 1602 IHYYFMALKNDEIIDATQKGNCSRFMNHSCEPNCETQKWTVNGQLRVGFFTTKLVPSGSE 1661
Query: 4882 LCYDYKFDFEDDQHKIPCHCGAVNCRKWM 4910
L +DY+F + + C CG+ NCR ++
Sbjct: 1662 LTFDYQFQRYGKEAQ-KCFCGSANCRGYL 1689
Score = 45.4 bits (106), Expect = 0.001
Identities = 62/281 (22%), Positives = 116/281 (41%), Gaps = 26/281 (9%)
Query: 2628 VPPSQQEQGHSVHSSSMVMRTLNHPLGGEFSEAPLSTSVPSETTSDNLQITTQPS--DGL 2685
VPP + G+S ++S LN P T P + L+I ++ S +
Sbjct: 1834 VPPLSEGDGYSSENTSRAHTPLNTPDPSTKLSTEADTDTPKKLMFRRLKIISENSMDSAI 1893
Query: 2686 EEKLDSDDPSVKELDVKDLEGVEVKDLDDEDLENLNLDTEDGKVVELDTLDNLETNDPNL 2745
+ + + D+ LE V V+ ++E+L++ L + ++D+ N+E +
Sbjct: 1894 SDATSELEGKDGKEDLDQLENVPVE--EEEELQSQQLLPQQLPECKVDSETNIEASK--- 1948
Query: 2746 DDLLRSGEFDIIAYTDPELDMGDK-KSMFNEELDLPIDDKLDNQCVSVEPKKKEQENKTL 2804
L + E + A +P+ G K + NEE P D+ + + +EQ +KT+
Sbjct: 1949 ---LPTSEPEADAEIEPKESNGTKLEEPINEE--TPSQDEEEGVSDVESERSQEQPDKTV 2003
Query: 2805 VLSDKHSPQKKSTVTNEVKTEVLSPNSKVESKCETEKNDENKDNV----DTPCSQASAHS 2860
+SD + K ++K EV K +++ E + +D V TP + S
Sbjct: 2004 DISDLAT--KLLDSWKDLK-EVYRIPKKSQTEKENTTTERGRDAVGFRDQTPAPKTPNRS 2060
Query: 2861 DLNDGEKTSLHPCDPDLFEKRTNRETAGPSANVIQASTQLP 2901
D +K + + EKR R + P ++ + T+ P
Sbjct: 2061 RERDPDKQTQNK------EKRKRRSSLSPPSSAYERGTKRP 2095
Score = 38.5 bits (88), Expect = 0.17
Identities = 59/277 (21%), Positives = 114/277 (41%), Gaps = 27/277 (9%)
Query: 1610 DPNNSWTSSAPTVEGENDTMSNAQRSTLKWEKEEALGEMATVAPVLYTNINFPNLKEEFP 1669
+P N T S EG +D S +RS + +K + ++AT ++ +LKE +
Sbjct: 1972 EPINEETPSQDEEEGVSDVES--ERSQEQPDKTVDISDLATKLLD-----SWKDLKEVY- 2023
Query: 1670 DWTTRVKQIAKLWRKASSQERAPYVQKARDNRAALRINKVQMSNDSMKRQQQQDSIDPSS 1729
R+ + ++ ++ ++ ER RD A + D K+ Q ++ S
Sbjct: 2024 ----RIPKKSQTEKENTTTERGRDAVGFRDQTPAPKTPNRSRERDPDKQTQNKEKRKRRS 2079
Query: 1730 RID--SELFKDPLKQRESEHEQEWKFRQQMRQKSKQQAKIEATQKLEQVKNEQQQQQQQQ 1787
+ S ++ K+ + ++ ++++R K + + E +KL + + Q++ Q+QQ
Sbjct: 2080 SLSPPSSAYERGTKRPDDRYDTPTS-KKKVRIKDRNKLSTEERRKLFEQEVAQREAQKQQ 2138
Query: 1788 FGSQHLLVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVF 1847
Q+L + S S G +P P G P Q++ PS P + +
Sbjct: 2139 QQMQNLGMTSPLPYDSLGYNAPHHPFAGYPPGYPMQAY-------VDPSNP--NAGKVLL 2189
Query: 1848 VKPQAPP---PPPAPSRIPIQDSLSQAQTSQPPSPQV 1881
P P P P P+ ++ ++ PP P V
Sbjct: 2190 PTPSMDPVCSPAPYDHAQPLVGHSTEPLSAPPPVPVV 2226
Score = 36.6 bits (83), Expect = 0.63
Identities = 31/126 (24%), Positives = 52/126 (41%), Gaps = 12/126 (9%)
Query: 3899 TPPASLPPTPPPMACQKMANGFATTEELAGKAGVLVSHEVTKTLGPKPFQLPFRPQDDLL 3958
+PP+S PP PPP +++ TE +A + H L P LP D+
Sbjct: 185 SPPSSPPPPPPPAQATTLSSPAPVTEPVA------LPHTPITVLMAAPVPLPV----DVA 234
Query: 3959 ARALAQGPKTVDVPASLPTPPHNNQEELRIQDHCGDRDTPDSFVPSSSPESVVGVEVSRY 4018
R+L + P + VP SL + +++H + + S +S +G +
Sbjct: 235 VRSLKE-PPIIIVPESLEADTKQDTISNSLEEHVTQILNEQADISSKKEDSHIGKD-EEI 292
Query: 4019 PDLSLV 4024
PD S +
Sbjct: 293 PDSSKI 298
Score = 34.3 bits (77), Expect = 3.1
Identities = 30/126 (23%), Positives = 49/126 (38%), Gaps = 11/126 (8%)
Query: 1778 NEQQQQQQQQFG---SQHLLVQSGSDTPSS-GIQSPL---TPQPGNGNMSPAQSF--HKE 1828
N+Q QQQ+ SQ + G P+ G+ SP TP P+ + ++
Sbjct: 2276 NQQSVSVQQQYSPAQSQATIYYQGQTCPTVYGVTSPYSQTTPPIVQSYAQPSLQYIQGQQ 2335
Query: 1829 LFTKQPPSTPTSTSSDDVFVKPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQ--VFSPGS 1886
+FT P ++ + P P PS + + ++L PP P+ V P
Sbjct: 2336 IFTAHPQGVVVQPAAAVTTIVAPGQPQPLQPSEMVVTNNLLDLPPPSPPKPKTIVLPPNW 2395
Query: 1887 SNSRPP 1892
+R P
Sbjct: 2396 KTARDP 2401
>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
Length = 1573
Score = 88.6 bits (218), Expect = 1e-16
Identities = 153/641 (23%), Positives = 225/641 (35%), Gaps = 103/641 (16%)
Query: 1800 DTPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVK----PQAPPP 1855
DTPS + TP G + P T+ P S PT D P+ PP
Sbjct: 941 DTPSGRGLAEGTPTAGK--LGPTLGAGT---TRSPGSPPTLRVHGDTGSPRKPWPERRPP 995
Query: 1856 PPAPSRI-PIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSF 1914
PA +R P S + + PP P + S S P S + A PP
Sbjct: 996 RPAATRTAPPTPSPGPSASPGPPGPALTSDSSRELTPHSALTSEATSDAPDTSPPTPDPA 1055
Query: 1915 SRRN-----SAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDT 1969
SR N ++ TP SSV L + P+ ++L S +T ++ + P +
Sbjct: 1056 SRTNPDLILTSPDFALSTPDSSVVPALTPEPSPTPLPTLPKELTSDPSTPSEVTSLSPTS 1115
Query: 1970 PRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARP 2029
+ +D P S VSE + PSP P + P
Sbjct: 1116 EQVPESDTTPDLDTTPYSSTVSEYSRSPD---------PSPSPH---------PTTTPDP 1157
Query: 2030 LLTPAPLDSGPGPFKTPMQP--PPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSH 2087
+ P P+ + P TP P P + P+ + S + P TP+P +H
Sbjct: 1158 TMAPDPITT-LNPTVTPHFPTTPHPTTTPHPTTITHSTMI-----PDPTTTPQPFTTITH 1211
Query: 2088 NQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQ 2147
+ P TP P F+ + P S P+ P TP P ++S
Sbjct: 1212 STM---IPDPTTTPQP------------FTTMQPTTTPHSTTPH--PTTTPHPTTITHST 1254
Query: 2148 SSGTARSNTDPYS--QPPGTPRPTTVDPYSQQPQ---TPRPSTQTDLFVTPVTNQRHSDP 2202
+ P++ QP P PTT + P TP P+T +TP DP
Sbjct: 1255 MIPDPTTTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTTPHPTTTPHPTMTP-------DP 1307
Query: 2203 YAHPPGTPRPGISVPYSQP-PATPRPRISEGFTRSS--------MTRPVLMPNQDPFLQA 2253
P T P P + P P TP P + T S ++ P L P P L
Sbjct: 1308 TTTPYPTTTPD---PTTTPHPTTPDPSSTPVITTVSLPTSLGTELSSPTLAPTVKPSLH- 1363
Query: 2254 AQNRGPALPGPLVRPPDTCSQTPR-PPGPGLSDTFSRVSPSAARDPYDQSPM-TPRSQSD 2311
P L P + SQ P P P L + SR S + + DP PRSQS
Sbjct: 1364 -----PQLTFTAPAPHTSTSQIPTLEPSPALESSPSRSSTATSMDPLSTEDFKPPRSQSP 1418
Query: 2312 SF-----GTSQTAHDVADQPRPGSEGSFCASSNSPMH------SQGQQFSGVSQLPGPVP 2360
+ T +A D+ P P + + P+ + GQ P P
Sbjct: 1419 NLTPPPTHTPHSASDLTVSPDPLLSPTAHPLDHPPLDPLTLGPTPGQSPGPHGPCVAPTP 1478
Query: 2361 TSGV--TDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKK 2399
V + V + A + Q Q+L +++ Q++Q+++
Sbjct: 1479 PVRVMACEPPALVELVAAVRDVGGQLQRLTQVVEQERQERQ 1519
Score = 47.0 bits (110), Expect = 5e-04
Identities = 119/576 (20%), Positives = 175/576 (30%), Gaps = 95/576 (16%)
Query: 2151 TARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGT- 2209
T TD PP T PT+ + ++ T T + T S P T
Sbjct: 870 TCTGYTDYDDYPPWTWDPTSREDLAKGTTTAGVPGHTLPWRTTRRPGSSSPAIRRLPDTG 929
Query: 2210 PRPGISVPYSQPPATPRPR-ISEGFTRSSMTRPVL------MPNQDPFLQAAQNRG-PAL 2261
+ G +P++ TP R ++EG + P L P P L+ + G P
Sbjct: 930 SKDGYKLPWTWD--TPSGRGLAEGTPTAGKLGPTLGAGTTRSPGSPPTLRVHGDTGSPRK 987
Query: 2262 PGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQSDSFGTSQTAHD 2321
P P RPP + PP P + S P A +TP S S TS
Sbjct: 988 PWPERRPPRPAATRTAPPTPSPGPSASPGPPGPALTSDSSRELTPHSALTSEATSDAPDT 1047
Query: 2322 VADQPRPGSEGSFCASSNSPMHSQGQQFSGV------SQLPGPVPT-----SGVTDTQNT 2370
P P S + SP + S V P P+PT + T +
Sbjct: 1048 SPPTPDPASRTNPDLILTSPDFALSTPDSSVVPALTPEPSPTPLPTLPKELTSDPSTPSE 1107
Query: 2371 VNMAQADTEKLRQRQKLREIILQQQQQKKIAGRQEKGSQDSPAVPHPGPLQHWQPENVNQ 2430
V +E++ + + L + SP+ PHP
Sbjct: 1108 VTSLSPTSEQVPESDTTPD--LDTTPYSSTVSEYSRSPDPSPS-PHP------------- 1151
Query: 2431 AFTRPPPPYPGNIRSPVAPPLGPRYAVFPKDQRGPYPPDVASMGMRPHGFRF--GFPGGS 2488
T P P + + + P + P + P P+P + M P F +
Sbjct: 1152 -TTTPDPTMAPDPITTLNPTVTPHFPTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTIT 1210
Query: 2489 HGTMPSQERFLVPPQQIQGSGVSPQLRRSVSVDMPRP---LNNSQMNNPVGLPQHFSPQS 2545
H TM P +P P P +++ + +P PQ F+
Sbjct: 1211 HSTMIPDPTTTPQPFTTMQPTTTPHSTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTMQ 1270
Query: 2546 LPVQQHNILGQAYIELRHRAPDGRQRLPFSAPPGSVVEASSNLRHGNFIPRPDF-PGPRH 2604
H P + P + + H P P P P
Sbjct: 1271 PTTMPH---------------------PTTTPHPTTTPHPTTTPHPTTTPHPTMTPDPTT 1309
Query: 2605 TDPMRRPPQGLPNQLPVHPDLEQVPPSQQEQGHSVHSSSMVMRTLNHP--LGGEFSEAPL 2662
T P P PD SS+ V+ T++ P LG E S L
Sbjct: 1310 TPYPTTTPDPTTTPHPTTPD---------------PSSTPVITTVSLPTSLGTELSSPTL 1354
Query: 2663 STSV------------PSETTSDNLQITTQPSDGLE 2686
+ +V P+ TS + T +PS LE
Sbjct: 1355 APTVKPSLHPQLTFTAPAPHTSTSQIPTLEPSPALE 1390
Score = 36.6 bits (83), Expect = 0.63
Identities = 36/127 (28%), Positives = 45/127 (35%), Gaps = 8/127 (6%)
Query: 3258 HAELIEDYRIKQQQQCAMAPPTMMPSVQPQPPLIPGATPPTMSQ--PTFPMVPQQLQHQQ 3315
H+ +I D Q M P T S P P P T T S P PQ Q
Sbjct: 1211 HSTMIPDPTTTPQPFTTMQPTTTPHSTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTMQ 1270
Query: 3316 HTTVISGHTSPVRMPSLPGWQPNSAPAHLPLNPPRIQPPIAQLPIKTCTPAPGTV---SN 3372
TT+ T+P + P P + P P + P P T TP P T +
Sbjct: 1271 PTTMPHPTTTP-HPTTTP--HPTTTPHPTTTPHPTMTPDPTTTPYPTTTPDPTTTPHPTT 1327
Query: 3373 ANPQSGP 3379
+P S P
Sbjct: 1328 PDPSSTP 1334
Score = 33.5 bits (75), Expect = 5.3
Identities = 37/168 (22%), Positives = 70/168 (41%), Gaps = 25/168 (14%)
Query: 2122 ISRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTP 2181
+ + T++ P P T + V + + P +QPP PTT +Q P P
Sbjct: 613 LEKTTTKAPGKMPKSTKKWVTKNAKR----------PTTQPP--VMPTTKHSRAQSP--P 658
Query: 2182 RPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPR-PRISEGFTRSSMTR 2240
++QT +T ++R + + P T P ++ TP+ PR R++ T
Sbjct: 659 DLTSQTTAALTTEASRRPTSEFTRRPTTEAPQRWTSHTTATLTPQAPR-----ERTTKTM 713
Query: 2241 PVLMPNQDPFLQAAQNRGPALPGPLVRP----PDTCSQTPRPPGPGLS 2284
++ Q P +++ ++P + P P+ ++P+ P P S
Sbjct: 714 -AMLTTQGPQEMTSESTIKSIPQASLEPSAEIPEGSPESPKDPAPSPS 760
Score = 33.1 bits (74), Expect = 7.0
Identities = 52/237 (21%), Positives = 92/237 (38%), Gaps = 35/237 (14%)
Query: 1412 LSSSSAPTKSGTHGPADDPLADISEVLNTDDDILGIISDDLAKSVDHSDIGP-VTDDPSS 1470
L+S + T P DP + T+ D++ + S D A S S + P +T +PS
Sbjct: 1036 LTSEATSDAPDTSPPTPDPAS------RTNPDLI-LTSPDFALSTPDSSVVPALTPEPSP 1088
Query: 1471 LPQPNVNQ--SSRPLSEEQLDGILSPELDKMVTDGAILGKLYKIPELGGKDVEDLFTAVL 1528
P P + + +S P + ++ LSP + V + L P +++ +
Sbjct: 1089 TPLPTLPKELTSDPSTPSEVTS-LSP-TSEQVPESDTTPDLDTTP----------YSSTV 1136
Query: 1529 SPANTQPTPLPQPPPPTQLLPIHNQDAFSRM-PLMNGLIGSSPH---------LPHNSL- 1577
S + P P P P P T P D + + P + ++PH + H+++
Sbjct: 1137 SEYSRSPDPSPSPHPTTTPDPTMAPDPITTLNPTVTPHFPTTPHPTTTPHPTTITHSTMI 1196
Query: 1578 -PPGSGLGTFSAIAQSS-YPDARDKNSAFNPMASDPNNSWTSSAPTVEGENDTMSNA 1632
P + F+ I S+ PD F M T+ PT T++++
Sbjct: 1197 PDPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHSTTPHPTTTPHPTTITHS 1253
>gi|5454004 D4, zinc and double PHD fingers family 2 [Homo sapiens]
Length = 391
Score = 88.2 bits (217), Expect = 2e-16
Identities = 35/89 (39%), Positives = 49/89 (55%), Gaps = 2/89 (2%)
Query: 969 GAEGRLLACSQCGQCYHPYCVSIK--ITKVVLSKGWRCLECTVCEACGKATDPGRLLLCD 1026
G L++CS CG+ HP C+ + V + W+C+EC C CG + + +LL CD
Sbjct: 287 GQPEELVSCSDCGRSGHPSCLQFTPVMMAAVKTYRWQCIECKCCNICGTSENDDQLLFCD 346
Query: 1027 DCDISYHTYCLDPPLQTVPKGGWKCKWCV 1055
DCD YH YCL P + P+G W C C+
Sbjct: 347 DCDRGYHMYCLTPSMSEPPEGSWSCHLCL 375
Score = 81.3 bits (199), Expect = 2e-14
Identities = 33/80 (41%), Positives = 42/80 (52%), Gaps = 3/80 (3%)
Query: 359 CTTCGQHYHGMCLD---IAVTPLKRAGWQCPECKVCQNCKQSGEDSKMLVCDTCDKGYHT 415
C+ CG+ H CL + + +K WQC ECK C C S D ++L CD CD+GYH
Sbjct: 295 CSDCGRSGHPSCLQFTPVMMAAVKTYRWQCIECKCCNICGTSENDDQLLFCDDCDRGYHM 354
Query: 416 FCLQPVMKSVPTNGWKCKNC 435
+CL P M P W C C
Sbjct: 355 YCLTPSMSEPPEGSWSCHLC 374
Score = 48.5 bits (114), Expect = 2e-04
Identities = 25/68 (36%), Positives = 37/68 (54%), Gaps = 6/68 (8%)
Query: 395 KQSGEDSKMLVCDTCDKGYHTFCLQ--PVMKS-VPTNGWKCKNCRICIECGTRSSSQWHH 451
K++G+ +++ C C + H CLQ PVM + V T W+C C+ C CGT S+
Sbjct: 284 KKTGQPEELVSCSDCGRSGHPSCLQFTPVMMAAVKTYRWQCIECKCCNICGT---SENDD 340
Query: 452 NCLICDNC 459
L CD+C
Sbjct: 341 QLLFCDDC 348
Score = 37.7 bits (86), Expect = 0.28
Identities = 30/125 (24%), Positives = 39/125 (31%), Gaps = 38/125 (30%)
Query: 1015 KATDPGRLLLCDDCDISYHTYCLD--PPLQTVPKG-GWKCKWCVWCRHCGATSAGLRCEW 1071
K P L+ C DC S H CL P + K W+C C C CG +
Sbjct: 285 KTGQPEELVSCSDCGRSGHPSCLQFTPVMMAAVKTYRWQCIECKCCNICGTS-------- 336
Query: 1072 QNNYTQCAPCASLSSCPVCYRNYREEDLILQCRQCDRWMHAVCQNLNTEEEVENVADIGF 1131
+D +L C CDR H C + E E +
Sbjct: 337 -----------------------ENDDQLLFCDDCDRGYHMYCLTPSMSEPPEG----SW 369
Query: 1132 DCSMC 1136
C +C
Sbjct: 370 SCHLC 374
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 87.4 bits (215), Expect = 3e-16
Identities = 104/424 (24%), Positives = 137/424 (32%), Gaps = 49/424 (11%)
Query: 1811 TPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAPPPPPAPSRIPIQDSLSQ 1870
TP P SP + L PS PT+T++ PPP PS PI
Sbjct: 1398 TPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTT--------TPPPTTTPSP-PI------ 1442
Query: 1871 AQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNSAAPVENCTPLS 1930
T+ PP SP S + P P + TP PP S + P TP
Sbjct: 1443 TTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSP 1502
Query: 1931 SVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPR------PVMTDQFPKSLGL 1984
+ P+ +T P ++TT P P P P T P +
Sbjct: 1503 PTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTT-- 1560
Query: 1985 SRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLLTPAP---LDSGPG 2041
+ SP + T P + T PSP I + P TP+P + P
Sbjct: 1561 TPSPPPTTTTTPPPTTTPSPPTTTTPSPPT-------ITTTTPPPTTTPSPPTTTTTTPP 1613
Query: 2042 PFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLTP 2101
P TP P + P S + + P TP P + P TP
Sbjct: 1614 PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPP--------TTTPSPPTTTTP 1665
Query: 2102 HPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQ 2161
P + + P T S P + P PP T + S + T P S
Sbjct: 1666 SPPITTTTTPPPTT-----TPSSPITTTP--SPPTTTMTTPSPTTTPSSPITTTTTPSST 1718
Query: 2162 PPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQP 2221
+P PTT+ S TP P T T + P T PP P S +
Sbjct: 1719 TTPSPPPTTMTTPSPTT-TPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTT 1777
Query: 2222 PATP 2225
P TP
Sbjct: 1778 PTTP 1781
Score = 80.5 bits (197), Expect = 4e-14
Identities = 124/593 (20%), Positives = 191/593 (32%), Gaps = 58/593 (9%)
Query: 1797 SGSDTPSSG---IQSPLTPQPG-NGNMSPAQSFHKELFTKQPPSTPTSTSSDDVF----V 1848
+G+ TP++ + +TP P G +P + T P TPT T +
Sbjct: 3754 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3813
Query: 1849 KPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPP 1908
P P P ++ P ++ T P +P + ++ P+ TP P
Sbjct: 3814 TTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTPITTTTTVTPTPT 3867
Query: 1909 PVGHSFSRRNSAAPVENCTPLSS-------VSRPLQMNETTANRPSPVRDLCSSSTTNND 1961
P G TP + + P+ T P+P ++T
Sbjct: 3868 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3927
Query: 1962 PYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQR 2021
P TP P T Q P + ++ + V+ P GT T P
Sbjct: 3928 TTTVTP-TPTPTGT-QTPTTTPITTTTTVTPT----PTPTGTQTPTTTPITTTTTVTPTP 3981
Query: 2022 IPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTP-R 2080
P P TP + P TP + P + + + + + P TP
Sbjct: 3982 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 4041
Query: 2081 PIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGT---ISRPTSQDPYSQPPGT 2137
+ + P TP P+ +Q T I+ T+ P P GT
Sbjct: 4042 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 4101
Query: 2138 PRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPS---TQTDLFVTPV 2194
P T + P P GT PTT + TP P+ TQT TP+
Sbjct: 4102 QTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-TTPI 4155
Query: 2195 TNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFTRSSMTRPVLMPNQDPFLQAA 2254
T P P GT P + + TP P + T P + P +
Sbjct: 4156 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT-----PTGTQTGPPTHTSTAPIAELT 4210
Query: 2255 QNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVS--PSAARDPYDQSPMTPRSQSDS 2312
+ P P + QT R L+++ + +S P A P TP + + +
Sbjct: 4211 TSNPP--------PESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTT 4262
Query: 2313 FG---TSQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTS 2362
G S P + G+ SS++P S Q + + P P P S
Sbjct: 4263 SGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLS 4315
Score = 76.6 bits (187), Expect = 6e-13
Identities = 105/439 (23%), Positives = 136/439 (30%), Gaps = 71/439 (16%)
Query: 1897 PYAKMVGTPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSS 1956
P K + TP PP + P + T L + P TT P
Sbjct: 1391 PMDKCITTPSPPTT-------TPSPPPTSTTTLPPTTTPSPPTTTTTTPP---------P 1434
Query: 1957 TTNNDPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADV 2016
TT P TP P T SP +S T P S T PSP
Sbjct: 1435 TTTPSPPITTTTTPPPTTTP----------SPPISTTTTPPPTTT-PSPPTTTPSPPTTT 1483
Query: 2017 FQRQRIPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQ--DPYGSVSQASRRLSVDPYER 2074
P TP P + P TP+ PP S+ P + S + + P
Sbjct: 1484 ------PSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPP--- 1534
Query: 2075 PALTPRPIDNFSHNQSNDPYSQPP-LTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQ 2133
P TP P + PP TP P + P P T + P+ P +
Sbjct: 1535 PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPS---PPTI 1591
Query: 2134 PPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQ---PQTPRPSTQTDLF 2190
TP P + S T + T P + P P T + P + P T PS
Sbjct: 1592 TTTTPPPTT---TPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTT 1648
Query: 2191 VTPVTNQRHSDPYAHPPGTP------RPGISVPYSQPPATPRPRISEGFTRSSMTRPVLM 2244
TP S P P P P + P S TP P + T S T P
Sbjct: 1649 TTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTP--- 1705
Query: 2245 PNQDPFLQAAQNRGPALPGPLVRPPDTC-----SQTPRPPGPGLSDTFSRVSPSAARDPY 2299
P P P PP T + TP PP + T + + P+ P
Sbjct: 1706 --SSPITTTTTPSSTTTPSP---PPTTMTTPSPTTTPSPP----TTTMTTLPPTTTSSPL 1756
Query: 2300 DQSPMTPRSQSDSFGTSQT 2318
+P+ P +F T
Sbjct: 1757 TTTPLPPSITPPTFSPFST 1775
Score = 71.2 bits (173), Expect = 2e-11
Identities = 127/609 (20%), Positives = 194/609 (31%), Gaps = 64/609 (10%)
Query: 1797 SGSDTPSSG---IQSPLTPQPG-NGNMSPAQSFHKELFTKQPPSTPTSTSSDDVF----V 1848
+G+ TP++ + +TP P G +P + T P TPT T +
Sbjct: 1960 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2019
Query: 1849 KPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPP 1908
P P P ++ P ++ T P +P + ++ P+ TP P
Sbjct: 2020 TTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTPITTTTTVTPTPT 2073
Query: 1909 PVGHSFSRRNSAAPVENCTPLSS-------VSRPLQMNETTANRPSPVRDLCSSSTTNND 1961
P G TP + + P+ T P+P ++T
Sbjct: 2074 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2133
Query: 1962 PYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQR 2021
P TP P T Q P + ++ + V+ P GT T P
Sbjct: 2134 TTTVTP-TPTPTGT-QTPTTTPITTTTTVTPT----PTPTGTQTPTTTPITTTTTVTPTP 2187
Query: 2022 IPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTP-R 2080
P P TP + P TP + P + + + + + P TP
Sbjct: 2188 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2247
Query: 2081 PIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGT---ISRPTSQDPYSQPPGT 2137
+ + P TP P+ +Q T I+ T+ P P GT
Sbjct: 2248 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2307
Query: 2138 PRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPS---TQTDLFVTPV 2194
P T + P P GT PTT + TP P+ TQT TP+
Sbjct: 2308 QTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-TTPI 2361
Query: 2195 TNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFTRSSMTRPV-----LMPNQDP 2249
T P P GT P + + TP P + T++ T P+ + P P
Sbjct: 2362 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTP 2419
Query: 2250 FLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQ 2309
P V P T + T P ++ T + V+P+ P TP +
Sbjct: 2420 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTPT----PTPTGTQTPTTT 2474
Query: 2310 SDSFGTSQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQN 2369
+ T+ T P P G + +P + + V+ P P T T T
Sbjct: 2475 PITTTTTVT-------PTPTPTG-----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2522
Query: 2370 TVNMAQADT 2378
T T
Sbjct: 2523 TTTTTVTPT 2531
Score = 71.2 bits (173), Expect = 2e-11
Identities = 127/609 (20%), Positives = 194/609 (31%), Gaps = 64/609 (10%)
Query: 1797 SGSDTPSSG---IQSPLTPQPG-NGNMSPAQSFHKELFTKQPPSTPTSTSSDDVF----V 1848
+G+ TP++ + +TP P G +P + T P TPT T +
Sbjct: 2098 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2157
Query: 1849 KPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPP 1908
P P P ++ P ++ T P +P + ++ P+ TP P
Sbjct: 2158 TTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTPITTTTTVTPTPT 2211
Query: 1909 PVGHSFSRRNSAAPVENCTPLSS-------VSRPLQMNETTANRPSPVRDLCSSSTTNND 1961
P G TP + + P+ T P+P ++T
Sbjct: 2212 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2271
Query: 1962 PYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQR 2021
P TP P T Q P + ++ + V+ P GT T P
Sbjct: 2272 TTTVTP-TPTPTGT-QTPTTTPITTTTTVTPT----PTPTGTQTPTTTPITTTTTVTPTP 2325
Query: 2022 IPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTP-R 2080
P P TP + P TP + P + + + + + P TP
Sbjct: 2326 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2385
Query: 2081 PIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGT---ISRPTSQDPYSQPPGT 2137
+ + P TP P+ +Q T I+ T+ P P GT
Sbjct: 2386 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2445
Query: 2138 PRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPS---TQTDLFVTPV 2194
P T + P P GT PTT + TP P+ TQT TP+
Sbjct: 2446 QTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-TTPI 2499
Query: 2195 TNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFTRSSMTRPV-----LMPNQDP 2249
T P P GT P + + TP P + T++ T P+ + P P
Sbjct: 2500 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTP 2557
Query: 2250 FLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQ 2309
P V P T + T P ++ T + V+P+ P TP +
Sbjct: 2558 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTPT----PTPTGTQTPTTT 2612
Query: 2310 SDSFGTSQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQN 2369
+ T+ T P P G + +P + + V+ P P T T T
Sbjct: 2613 PITTTTTVT-------PTPTPTG-----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2660
Query: 2370 TVNMAQADT 2378
T T
Sbjct: 2661 TTTTTVTPT 2669
Score = 71.2 bits (173), Expect = 2e-11
Identities = 127/609 (20%), Positives = 194/609 (31%), Gaps = 64/609 (10%)
Query: 1797 SGSDTPSSG---IQSPLTPQPG-NGNMSPAQSFHKELFTKQPPSTPTSTSSDDVF----V 1848
+G+ TP++ + +TP P G +P + T P TPT T +
Sbjct: 2236 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2295
Query: 1849 KPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPP 1908
P P P ++ P ++ T P +P + ++ P+ TP P
Sbjct: 2296 TTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTPITTTTTVTPTPT 2349
Query: 1909 PVGHSFSRRNSAAPVENCTPLSS-------VSRPLQMNETTANRPSPVRDLCSSSTTNND 1961
P G TP + + P+ T P+P ++T
Sbjct: 2350 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2409
Query: 1962 PYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQR 2021
P TP P T Q P + ++ + V+ P GT T P
Sbjct: 2410 TTTVTP-TPTPTGT-QTPTTTPITTTTTVTPT----PTPTGTQTPTTTPITTTTTVTPTP 2463
Query: 2022 IPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTP-R 2080
P P TP + P TP + P + + + + + P TP
Sbjct: 2464 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2523
Query: 2081 PIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGT---ISRPTSQDPYSQPPGT 2137
+ + P TP P+ +Q T I+ T+ P P GT
Sbjct: 2524 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2583
Query: 2138 PRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPS---TQTDLFVTPV 2194
P T + P P GT PTT + TP P+ TQT TP+
Sbjct: 2584 QTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-TTPI 2637
Query: 2195 TNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFTRSSMTRPV-----LMPNQDP 2249
T P P GT P + + TP P + T++ T P+ + P P
Sbjct: 2638 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTP 2695
Query: 2250 FLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQ 2309
P V P T + T P ++ T + V+P+ P TP +
Sbjct: 2696 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTPT----PTPTGTQTPTTT 2750
Query: 2310 SDSFGTSQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQN 2369
+ T+ T P P G + +P + + V+ P P T T T
Sbjct: 2751 PITTTTTVT-------PTPTPTG-----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2798
Query: 2370 TVNMAQADT 2378
T T
Sbjct: 2799 TTTTTVTPT 2807
Score = 71.2 bits (173), Expect = 2e-11
Identities = 127/609 (20%), Positives = 194/609 (31%), Gaps = 64/609 (10%)
Query: 1797 SGSDTPSSG---IQSPLTPQPG-NGNMSPAQSFHKELFTKQPPSTPTSTSSDDVF----V 1848
+G+ TP++ + +TP P G +P + T P TPT T +
Sbjct: 2374 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2433
Query: 1849 KPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPP 1908
P P P ++ P ++ T P +P + ++ P+ TP P
Sbjct: 2434 TTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTPITTTTTVTPTPT 2487
Query: 1909 PVGHSFSRRNSAAPVENCTPLSS-------VSRPLQMNETTANRPSPVRDLCSSSTTNND 1961
P G TP + + P+ T P+P ++T
Sbjct: 2488 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2547
Query: 1962 PYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQR 2021
P TP P T Q P + ++ + V+ P GT T P
Sbjct: 2548 TTTVTP-TPTPTGT-QTPTTTPITTTTTVTPT----PTPTGTQTPTTTPITTTTTVTPTP 2601
Query: 2022 IPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTP-R 2080
P P TP + P TP + P + + + + + P TP
Sbjct: 2602 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2661
Query: 2081 PIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGT---ISRPTSQDPYSQPPGT 2137
+ + P TP P+ +Q T I+ T+ P P GT
Sbjct: 2662 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2721
Query: 2138 PRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPS---TQTDLFVTPV 2194
P T + P P GT PTT + TP P+ TQT TP+
Sbjct: 2722 QTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-TTPI 2775
Query: 2195 TNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFTRSSMTRPV-----LMPNQDP 2249
T P P GT P + + TP P + T++ T P+ + P P
Sbjct: 2776 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTP 2833
Query: 2250 FLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQ 2309
P V P T + T P ++ T + V+P+ P TP +
Sbjct: 2834 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTPT----PTPTGTQTPTTT 2888
Query: 2310 SDSFGTSQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQN 2369
+ T+ T P P G + +P + + V+ P P T T T
Sbjct: 2889 PITTTTTVT-------PTPTPTG-----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2936
Query: 2370 TVNMAQADT 2378
T T
Sbjct: 2937 TTTTTVTPT 2945
Score = 71.2 bits (173), Expect = 2e-11
Identities = 127/609 (20%), Positives = 194/609 (31%), Gaps = 64/609 (10%)
Query: 1797 SGSDTPSSG---IQSPLTPQPG-NGNMSPAQSFHKELFTKQPPSTPTSTSSDDVF----V 1848
+G+ TP++ + +TP P G +P + T P TPT T +
Sbjct: 2512 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2571
Query: 1849 KPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPP 1908
P P P ++ P ++ T P +P + ++ P+ TP P
Sbjct: 2572 TTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTPITTTTTVTPTPT 2625
Query: 1909 PVGHSFSRRNSAAPVENCTPLSS-------VSRPLQMNETTANRPSPVRDLCSSSTTNND 1961
P G TP + + P+ T P+P ++T
Sbjct: 2626 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2685
Query: 1962 PYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQR 2021
P TP P T Q P + ++ + V+ P GT T P
Sbjct: 2686 TTTVTP-TPTPTGT-QTPTTTPITTTTTVTPT----PTPTGTQTPTTTPITTTTTVTPTP 2739
Query: 2022 IPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTP-R 2080
P P TP + P TP + P + + + + + P TP
Sbjct: 2740 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2799
Query: 2081 PIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGT---ISRPTSQDPYSQPPGT 2137
+ + P TP P+ +Q T I+ T+ P P GT
Sbjct: 2800 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2859
Query: 2138 PRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPS---TQTDLFVTPV 2194
P T + P P GT PTT + TP P+ TQT TP+
Sbjct: 2860 QTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-TTPI 2913
Query: 2195 TNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFTRSSMTRPV-----LMPNQDP 2249
T P P GT P + + TP P + T++ T P+ + P P
Sbjct: 2914 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTP 2971
Query: 2250 FLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQ 2309
P V P T + T P ++ T + V+P+ P TP +
Sbjct: 2972 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTPT----PTPTGTQTPTTT 3026
Query: 2310 SDSFGTSQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQN 2369
+ T+ T P P G + +P + + V+ P P T T T
Sbjct: 3027 PITTTTTVT-------PTPTPTG-----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3074
Query: 2370 TVNMAQADT 2378
T T
Sbjct: 3075 TTTTTVTPT 3083
Score = 71.2 bits (173), Expect = 2e-11
Identities = 127/609 (20%), Positives = 194/609 (31%), Gaps = 64/609 (10%)
Query: 1797 SGSDTPSSG---IQSPLTPQPG-NGNMSPAQSFHKELFTKQPPSTPTSTSSDDVF----V 1848
+G+ TP++ + +TP P G +P + T P TPT T +
Sbjct: 2650 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2709
Query: 1849 KPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPP 1908
P P P ++ P ++ T P +P + ++ P+ TP P
Sbjct: 2710 TTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTPITTTTTVTPTPT 2763
Query: 1909 PVGHSFSRRNSAAPVENCTPLSS-------VSRPLQMNETTANRPSPVRDLCSSSTTNND 1961
P G TP + + P+ T P+P ++T
Sbjct: 2764 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2823
Query: 1962 PYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQR 2021
P TP P T Q P + ++ + V+ P GT T P
Sbjct: 2824 TTTVTP-TPTPTGT-QTPTTTPITTTTTVTPT----PTPTGTQTPTTTPITTTTTVTPTP 2877
Query: 2022 IPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTP-R 2080
P P TP + P TP + P + + + + + P TP
Sbjct: 2878 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2937
Query: 2081 PIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGT---ISRPTSQDPYSQPPGT 2137
+ + P TP P+ +Q T I+ T+ P P GT
Sbjct: 2938 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2997
Query: 2138 PRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPS---TQTDLFVTPV 2194
P T + P P GT PTT + TP P+ TQT TP+
Sbjct: 2998 QTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-TTPI 3051
Query: 2195 TNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFTRSSMTRPV-----LMPNQDP 2249
T P P GT P + + TP P + T++ T P+ + P P
Sbjct: 3052 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTP 3109
Query: 2250 FLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQ 2309
P V P T + T P ++ T + V+P+ P TP +
Sbjct: 3110 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTPT----PTPTGTQTPTTT 3164
Query: 2310 SDSFGTSQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQN 2369
+ T+ T P P G + +P + + V+ P P T T T
Sbjct: 3165 PITTTTTVT-------PTPTPTG-----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3212
Query: 2370 TVNMAQADT 2378
T T
Sbjct: 3213 TTTTTVTPT 3221
Score = 71.2 bits (173), Expect = 2e-11
Identities = 127/609 (20%), Positives = 194/609 (31%), Gaps = 64/609 (10%)
Query: 1797 SGSDTPSSG---IQSPLTPQPG-NGNMSPAQSFHKELFTKQPPSTPTSTSSDDVF----V 1848
+G+ TP++ + +TP P G +P + T P TPT T +
Sbjct: 2788 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2847
Query: 1849 KPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPP 1908
P P P ++ P ++ T P +P + ++ P+ TP P
Sbjct: 2848 TTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTPITTTTTVTPTPT 2901
Query: 1909 PVGHSFSRRNSAAPVENCTPLSS-------VSRPLQMNETTANRPSPVRDLCSSSTTNND 1961
P G TP + + P+ T P+P ++T
Sbjct: 2902 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2961
Query: 1962 PYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQR 2021
P TP P T Q P + ++ + V+ P GT T P
Sbjct: 2962 TTTVTP-TPTPTGT-QTPTTTPITTTTTVTPT----PTPTGTQTPTTTPITTTTTVTPTP 3015
Query: 2022 IPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTP-R 2080
P P TP + P TP + P + + + + + P TP
Sbjct: 3016 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3075
Query: 2081 PIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGT---ISRPTSQDPYSQPPGT 2137
+ + P TP P+ +Q T I+ T+ P P GT
Sbjct: 3076 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3135
Query: 2138 PRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPS---TQTDLFVTPV 2194
P T + P P GT PTT + TP P+ TQT TP+
Sbjct: 3136 QTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-TTPI 3189
Query: 2195 TNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFTRSSMTRPV-----LMPNQDP 2249
T P P GT P + + TP P + T++ T P+ + P P
Sbjct: 3190 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTP 3247
Query: 2250 FLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQ 2309
P V P T + T P ++ T + V+P+ P TP +
Sbjct: 3248 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTPT----PTPTGTQTPTTT 3302
Query: 2310 SDSFGTSQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQN 2369
+ T+ T P P G + +P + + V+ P P T T T
Sbjct: 3303 PITTTTTVT-------PTPTPTG-----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3350
Query: 2370 TVNMAQADT 2378
T T
Sbjct: 3351 TTTTTVTPT 3359
Score = 71.2 bits (173), Expect = 2e-11
Identities = 127/609 (20%), Positives = 194/609 (31%), Gaps = 64/609 (10%)
Query: 1797 SGSDTPSSG---IQSPLTPQPG-NGNMSPAQSFHKELFTKQPPSTPTSTSSDDVF----V 1848
+G+ TP++ + +TP P G +P + T P TPT T +
Sbjct: 2926 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2985
Query: 1849 KPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPP 1908
P P P ++ P ++ T P +P + ++ P+ TP P
Sbjct: 2986 TTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTPITTTTTVTPTPT 3039
Query: 1909 PVGHSFSRRNSAAPVENCTPLSS-------VSRPLQMNETTANRPSPVRDLCSSSTTNND 1961
P G TP + + P+ T P+P ++T
Sbjct: 3040 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3099
Query: 1962 PYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQR 2021
P TP P T Q P + ++ + V+ P GT T P
Sbjct: 3100 TTTVTP-TPTPTGT-QTPTTTPITTTTTVTPT----PTPTGTQTPTTTPITTTTTVTPTP 3153
Query: 2022 IPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTP-R 2080
P P TP + P TP + P + + + + + P TP
Sbjct: 3154 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3213
Query: 2081 PIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGT---ISRPTSQDPYSQPPGT 2137
+ + P TP P+ +Q T I+ T+ P P GT
Sbjct: 3214 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3273
Query: 2138 PRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPS---TQTDLFVTPV 2194
P T + P P GT PTT + TP P+ TQT TP+
Sbjct: 3274 QTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-TTPI 3327
Query: 2195 TNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFTRSSMTRPV-----LMPNQDP 2249
T P P GT P + + TP P + T++ T P+ + P P
Sbjct: 3328 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTP 3385
Query: 2250 FLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQ 2309
P V P T + T P ++ T + V+P+ P TP +
Sbjct: 3386 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTPT----PTPTGTQTPTTT 3440
Query: 2310 SDSFGTSQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQN 2369
+ T+ T P P G + +P + + V+ P P T T T
Sbjct: 3441 PITTTTTVT-------PTPTPTG-----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3488
Query: 2370 TVNMAQADT 2378
T T
Sbjct: 3489 TTTTTVTPT 3497
Score = 71.2 bits (173), Expect = 2e-11
Identities = 127/609 (20%), Positives = 194/609 (31%), Gaps = 64/609 (10%)
Query: 1797 SGSDTPSSG---IQSPLTPQPG-NGNMSPAQSFHKELFTKQPPSTPTSTSSDDVF----V 1848
+G+ TP++ + +TP P G +P + T P TPT T +
Sbjct: 3064 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3123
Query: 1849 KPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPP 1908
P P P ++ P ++ T P +P + ++ P+ TP P
Sbjct: 3124 TTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTPITTTTTVTPTPT 3177
Query: 1909 PVGHSFSRRNSAAPVENCTPLSS-------VSRPLQMNETTANRPSPVRDLCSSSTTNND 1961
P G TP + + P+ T P+P ++T
Sbjct: 3178 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3237
Query: 1962 PYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQR 2021
P TP P T Q P + ++ + V+ P GT T P
Sbjct: 3238 TTTVTP-TPTPTGT-QTPTTTPITTTTTVTPT----PTPTGTQTPTTTPITTTTTVTPTP 3291
Query: 2022 IPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTP-R 2080
P P TP + P TP + P + + + + + P TP
Sbjct: 3292 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3351
Query: 2081 PIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGT---ISRPTSQDPYSQPPGT 2137
+ + P TP P+ +Q T I+ T+ P P GT
Sbjct: 3352 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3411
Query: 2138 PRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPS---TQTDLFVTPV 2194
P T + P P GT PTT + TP P+ TQT TP+
Sbjct: 3412 QTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-TTPI 3465
Query: 2195 TNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFTRSSMTRPV-----LMPNQDP 2249
T P P GT P + + TP P + T++ T P+ + P P
Sbjct: 3466 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTP 3523
Query: 2250 FLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQ 2309
P V P T + T P ++ T + V+P+ P TP +
Sbjct: 3524 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTPT----PTPTGTQTPTTT 3578
Query: 2310 SDSFGTSQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQN 2369
+ T+ T P P G + +P + + V+ P P T T T
Sbjct: 3579 PITTTTTVT-------PTPTPTG-----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3626
Query: 2370 TVNMAQADT 2378
T T
Sbjct: 3627 TTTTTVTPT 3635
Score = 71.2 bits (173), Expect = 2e-11
Identities = 127/609 (20%), Positives = 194/609 (31%), Gaps = 64/609 (10%)
Query: 1797 SGSDTPSSG---IQSPLTPQPG-NGNMSPAQSFHKELFTKQPPSTPTSTSSDDVF----V 1848
+G+ TP++ + +TP P G +P + T P TPT T +
Sbjct: 3202 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3261
Query: 1849 KPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPP 1908
P P P ++ P ++ T P +P + ++ P+ TP P
Sbjct: 3262 TTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTPITTTTTVTPTPT 3315
Query: 1909 PVGHSFSRRNSAAPVENCTPLSS-------VSRPLQMNETTANRPSPVRDLCSSSTTNND 1961
P G TP + + P+ T P+P ++T
Sbjct: 3316 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3375
Query: 1962 PYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQR 2021
P TP P T Q P + ++ + V+ P GT T P
Sbjct: 3376 TTTVTP-TPTPTGT-QTPTTTPITTTTTVTPT----PTPTGTQTPTTTPITTTTTVTPTP 3429
Query: 2022 IPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTP-R 2080
P P TP + P TP + P + + + + + P TP
Sbjct: 3430 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3489
Query: 2081 PIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGT---ISRPTSQDPYSQPPGT 2137
+ + P TP P+ +Q T I+ T+ P P GT
Sbjct: 3490 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3549
Query: 2138 PRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPS---TQTDLFVTPV 2194
P T + P P GT PTT + TP P+ TQT TP+
Sbjct: 3550 QTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-TTPI 3603
Query: 2195 TNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFTRSSMTRPV-----LMPNQDP 2249
T P P GT P + + TP P + T++ T P+ + P P
Sbjct: 3604 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTP 3661
Query: 2250 FLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQ 2309
P V P T + T P ++ T + V+P+ P TP +
Sbjct: 3662 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTPT----PTPTGTQTPTTT 3716
Query: 2310 SDSFGTSQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQN 2369
+ T+ T P P G + +P + + V+ P P T T T
Sbjct: 3717 PITTTTTVT-------PTPTPTG-----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3764
Query: 2370 TVNMAQADT 2378
T T
Sbjct: 3765 TTTTTVTPT 3773
Score = 71.2 bits (173), Expect = 2e-11
Identities = 127/609 (20%), Positives = 194/609 (31%), Gaps = 64/609 (10%)
Query: 1797 SGSDTPSSG---IQSPLTPQPG-NGNMSPAQSFHKELFTKQPPSTPTSTSSDDVF----V 1848
+G+ TP++ + +TP P G +P + T P TPT T +
Sbjct: 3340 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3399
Query: 1849 KPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPP 1908
P P P ++ P ++ T P +P + ++ P+ TP P
Sbjct: 3400 TTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTPITTTTTVTPTPT 3453
Query: 1909 PVGHSFSRRNSAAPVENCTPLSS-------VSRPLQMNETTANRPSPVRDLCSSSTTNND 1961
P G TP + + P+ T P+P ++T
Sbjct: 3454 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3513
Query: 1962 PYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQR 2021
P TP P T Q P + ++ + V+ P GT T P
Sbjct: 3514 TTTVTP-TPTPTGT-QTPTTTPITTTTTVTPT----PTPTGTQTPTTTPITTTTTVTPTP 3567
Query: 2022 IPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTP-R 2080
P P TP + P TP + P + + + + + P TP
Sbjct: 3568 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3627
Query: 2081 PIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGT---ISRPTSQDPYSQPPGT 2137
+ + P TP P+ +Q T I+ T+ P P GT
Sbjct: 3628 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3687
Query: 2138 PRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPS---TQTDLFVTPV 2194
P T + P P GT PTT + TP P+ TQT TP+
Sbjct: 3688 QTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-TTPI 3741
Query: 2195 TNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFTRSSMTRPV-----LMPNQDP 2249
T P P GT P + + TP P + T++ T P+ + P P
Sbjct: 3742 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTP 3799
Query: 2250 FLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQ 2309
P V P T + T P ++ T + V+P+ P TP +
Sbjct: 3800 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTPT----PTPTGTQTPTTT 3854
Query: 2310 SDSFGTSQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQN 2369
+ T+ T P P G + +P + + V+ P P T T T
Sbjct: 3855 PITTTTTVT-------PTPTPTG-----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3902
Query: 2370 TVNMAQADT 2378
T T
Sbjct: 3903 TTTTTVTPT 3911
Score = 71.2 bits (173), Expect = 2e-11
Identities = 127/609 (20%), Positives = 194/609 (31%), Gaps = 64/609 (10%)
Query: 1797 SGSDTPSSG---IQSPLTPQPG-NGNMSPAQSFHKELFTKQPPSTPTSTSSDDVF----V 1848
+G+ TP++ + +TP P G +P + T P TPT T +
Sbjct: 3478 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3537
Query: 1849 KPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPP 1908
P P P ++ P ++ T P +P + ++ P+ TP P
Sbjct: 3538 TTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTPITTTTTVTPTPT 3591
Query: 1909 PVGHSFSRRNSAAPVENCTPLSS-------VSRPLQMNETTANRPSPVRDLCSSSTTNND 1961
P G TP + + P+ T P+P ++T
Sbjct: 3592 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3651
Query: 1962 PYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQR 2021
P TP P T Q P + ++ + V+ P GT T P
Sbjct: 3652 TTTVTP-TPTPTGT-QTPTTTPITTTTTVTPT----PTPTGTQTPTTTPITTTTTVTPTP 3705
Query: 2022 IPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTP-R 2080
P P TP + P TP + P + + + + + P TP
Sbjct: 3706 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3765
Query: 2081 PIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGT---ISRPTSQDPYSQPPGT 2137
+ + P TP P+ +Q T I+ T+ P P GT
Sbjct: 3766 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3825
Query: 2138 PRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPS---TQTDLFVTPV 2194
P T + P P GT PTT + TP P+ TQT TP+
Sbjct: 3826 QTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-TTPI 3879
Query: 2195 TNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFTRSSMTRPV-----LMPNQDP 2249
T P P GT P + + TP P + T++ T P+ + P P
Sbjct: 3880 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTP 3937
Query: 2250 FLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQ 2309
P V P T + T P ++ T + V+P+ P TP +
Sbjct: 3938 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTPT----PTPTGTQTPTTT 3992
Query: 2310 SDSFGTSQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQN 2369
+ T+ T P P G + +P + + V+ P P T T T
Sbjct: 3993 PITTTTTVT-------PTPTPTG-----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4040
Query: 2370 TVNMAQADT 2378
T T
Sbjct: 4041 TTTTTVTPT 4049
Score = 71.2 bits (173), Expect = 2e-11
Identities = 127/609 (20%), Positives = 194/609 (31%), Gaps = 64/609 (10%)
Query: 1797 SGSDTPSSG---IQSPLTPQPG-NGNMSPAQSFHKELFTKQPPSTPTSTSSDDVF----V 1848
+G+ TP++ + +TP P G +P + T P TPT T +
Sbjct: 3616 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 3675
Query: 1849 KPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPP 1908
P P P ++ P ++ T P +P + ++ P+ TP P
Sbjct: 3676 TTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTPITTTTTVTPTPT 3729
Query: 1909 PVGHSFSRRNSAAPVENCTPLSS-------VSRPLQMNETTANRPSPVRDLCSSSTTNND 1961
P G TP + + P+ T P+P ++T
Sbjct: 3730 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3789
Query: 1962 PYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQR 2021
P TP P T Q P + ++ + V+ P GT T P
Sbjct: 3790 TTTVTP-TPTPTGT-QTPTTTPITTTTTVTPT----PTPTGTQTPTTTPITTTTTVTPTP 3843
Query: 2022 IPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTP-R 2080
P P TP + P TP + P + + + + + P TP
Sbjct: 3844 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 3903
Query: 2081 PIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGT---ISRPTSQDPYSQPPGT 2137
+ + P TP P+ +Q T I+ T+ P P GT
Sbjct: 3904 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3963
Query: 2138 PRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPS---TQTDLFVTPV 2194
P T + P P GT PTT + TP P+ TQT TP+
Sbjct: 3964 QTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-TTPI 4017
Query: 2195 TNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFTRSSMTRPV-----LMPNQDP 2249
T P P GT P + + TP P + T++ T P+ + P P
Sbjct: 4018 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTP 4075
Query: 2250 FLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQ 2309
P V P T + T P ++ T + V+P+ P TP +
Sbjct: 4076 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTPT----PTPTGTQTPTTT 4130
Query: 2310 SDSFGTSQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQN 2369
+ T+ T P P G + +P + + V+ P P T T T
Sbjct: 4131 PITTTTTVT-------PTPTPTG-----TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4178
Query: 2370 TVNMAQADT 2378
T T
Sbjct: 4179 TTTTTVTPT 4187
Score = 66.6 bits (161), Expect = 6e-10
Identities = 117/558 (20%), Positives = 179/558 (32%), Gaps = 72/558 (12%)
Query: 1834 PPSTPTSTSSDDVFVKPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPS 1893
PP+T T++ V P P P ++ P ++ T P +P + ++ P+
Sbjct: 1895 PPTTTPITTTTTV-----TPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPT 1943
Query: 1894 PMDPYAKMVGTPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLC 1953
TP P P G ++ + P+ T ++ P T +P+
Sbjct: 1944 TTPITTTTTVTPTPTPTG---TQTPTTTPITTTTTVTPTPTPTGTQTPTT---TPI---- 1993
Query: 1954 SSSTTNNDPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKG-PIAAGTSDHFTKPSP 2012
++TT P P T P T P+ + T P GT T P
Sbjct: 1994 -TTTTTVTPTPTPTGTQTPTTT------------PITTTTTVTPTPTPTGTQTPTTTPIT 2040
Query: 2013 RADVFQRQRIPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPY 2072
P P TP + P TP + P + + + +
Sbjct: 2041 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2100
Query: 2073 ERPALTP-RPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGT---ISRPTSQ 2128
+ P TP + + P TP P+ +Q T I+ T+
Sbjct: 2101 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2160
Query: 2129 DPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPS---T 2185
P P GT P T + P P GT PTT + TP P+ T
Sbjct: 2161 TPTPTPTGTQTPTTTPI-----TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2215
Query: 2186 QTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFTRSSMTRPV--- 2242
QT TP+T P P GT P + + TP P + T++ T P+
Sbjct: 2216 QTPT-TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTT 2272
Query: 2243 --LMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYD 2300
+ P P P V P T + T P ++ T + V+P+ P
Sbjct: 2273 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTPT----PTP 2327
Query: 2301 QSPMTPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVP 2360
TP + + T+ T P P G + +P + + V+ P P
Sbjct: 2328 TGTQTPTTTPITTTTTVT-------PTPTPTG-----TQTPTTTPITTTTTVTPTPTPTG 2375
Query: 2361 TSGVTDTQNTVNMAQADT 2378
T T T T T
Sbjct: 2376 TQTPTTTPITTTTTVTPT 2393
Score = 65.9 bits (159), Expect = 1e-09
Identities = 134/614 (21%), Positives = 202/614 (32%), Gaps = 93/614 (15%)
Query: 1801 TPSSGIQSPLTPQPGNGNMSPAQ--SFHKELFTKQPPST----PTSTSSDDVFVKPQAPP 1854
TPS +P+TP + P S T PP+T PT+T+ + PP
Sbjct: 1538 TPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPP 1597
Query: 1855 PPPAPSRIPIQDSLSQAQTSQPPSPQ---VFSPGSSNSRPPSPMDPYAKMVGTPRPPPVG 1911
P PS P + + T+ P P + P S+ + PP+ TP PPP
Sbjct: 1598 PTTTPSP-PTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTT---------TPSPPPT- 1646
Query: 1912 HSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPR 1971
+ P TP + TT P P S TT P TP
Sbjct: 1647 ------TTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPS 1700
Query: 1972 PVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLL 2031
P T P + + +P + + P T T PSP + P
Sbjct: 1701 PTTTPSSP--ITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTM-------TTLPPTT 1751
Query: 2032 TPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSN 2091
T +PL + P P P PP+ P+ + + + + + + + +P NF +
Sbjct: 1752 TSSPLTTTPLP---PSITPPTF-SPFSTTTPTTPCVPLCNWTGWLDSGKP--NFHKPGGD 1805
Query: 2092 DPYSQPPLTPHPAVN---ESFAHPSRAFSQPG-----TISRPTSQDPYSQPPGTPRPVV- 2142
P A N + +P Q G +S Q PG P+
Sbjct: 1806 TELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAF 1865
Query: 2143 -----------DSYSQSSGTARSNTDPYSQPPGTP--RPTTVDPYSQQPQTPRPSTQTDL 2189
+ +Q + + T+ + P TP TTV P TP P+
Sbjct: 1866 CLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTP------TPTPTGTQTP 1919
Query: 2190 FVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFTRSSMTRPV-----LM 2244
TP+T P P GT P + + TP P + T++ T P+ +
Sbjct: 1920 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 1977
Query: 2245 PNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPM 2304
P P P V P T + T P ++ T + V+P+ P
Sbjct: 1978 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT-TTVTPT----PTPTGTQ 2032
Query: 2305 TPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTSGV 2364
TP + + T+ T P P G + +P + + V+ P P T
Sbjct: 2033 TPTTTPITTTTTVT-------PTPTPTG-----TQTPTTTPITTTTTVTPTPTPTGTQTP 2080
Query: 2365 TDTQNTVNMAQADT 2378
T T T T
Sbjct: 2081 TTTPITTTTTVTPT 2094
Score = 57.0 bits (136), Expect = 5e-07
Identities = 79/360 (21%), Positives = 116/360 (32%), Gaps = 52/360 (14%)
Query: 2040 PGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPL 2099
P P T PPP+S + S + P TP P + P
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSP------PITTTTTPPPTT 1452
Query: 2100 TPHPAVNESFA-HPSRAFSQPGTISRPTSQDP------YSQPPGTPRPVVDSYSQSSGTA 2152
TP P ++ + P+ S P T P + P + PP T P + + + A
Sbjct: 1453 TPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPA 1512
Query: 2153 RSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRP 2212
+ T P + P P TT P P T PS T +TP T+ P P P
Sbjct: 1513 STTTLPPTTTPSPPTTTTTTP----PPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTT 1568
Query: 2213 GISVPYSQPPATPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRGPALPGP-------- 2264
+ P + P+ P T ++ T P P P P
Sbjct: 1569 TTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP 1628
Query: 2265 -----------LVRPPDTCSQTPRP---PGPGLSDTFSRVSPSAARDPYDQSPMTPRSQS 2310
PP T + TP P P P + T S + P +P +P + +
Sbjct: 1629 PTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTT 1688
Query: 2311 DSFGTSQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQNT 2370
S T+ P P + S ++ + S + P P PT+ T + T
Sbjct: 1689 PSPPTT-----TMTTPSPTTTPSSPITTTTTPSS--------TTTPSPPPTTMTTPSPTT 1735
Score = 53.9 bits (128), Expect = 4e-06
Identities = 101/456 (22%), Positives = 141/456 (30%), Gaps = 88/456 (19%)
Query: 1932 VSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTDQFPKSLGLSRSPVVS 1991
V++P M TT P+P ++TT P P T P T P+ +
Sbjct: 1879 VTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTT------------PITT 1926
Query: 1992 EQTAKG-PIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDSGPGPFKTPMQPP 2050
T P GT T P P P TP + TP P
Sbjct: 1927 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV----TPTPTP 1982
Query: 2051 PSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFA 2110
+Q P + + + +V P TP P P TP
Sbjct: 1983 TGTQTP--TTTPITTTTTVTP------TPTPTGT----------QTPTTTP--------- 2015
Query: 2111 HPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTT 2170
I+ T+ P P GT P T + P P GT PTT
Sbjct: 2016 -----------ITTTTTVTPTPTPTGTQTPTTTPI-----TTTTTVTPTPTPTGTQTPTT 2059
Query: 2171 VDPYSQQPQTPRPS---TQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRP 2227
+ TP P+ TQT TP+T P P GT P + + TP P
Sbjct: 2060 TPITTTTTVTPTPTPTGTQTPT-TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2118
Query: 2228 RISEGFTRSSMTRPV-----LMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPG 2282
+ T++ T P+ + P P P V P T + T P
Sbjct: 2119 --TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2176
Query: 2283 LSDTFSRVSPSAARDPYDQSPMTPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSNSPM 2342
++ T + V+P+ P TP + + T+ T P P G + +P
Sbjct: 2177 ITTT-TTVTPT----PTPTGTQTPTTTPITTTTTVT-------PTPTPTG-----TQTPT 2219
Query: 2343 HSQGQQFSGVSQLPGPVPTSGVTDTQNTVNMAQADT 2378
+ + V+ P P T T T T T
Sbjct: 2220 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2255
Score = 47.0 bits (110), Expect = 5e-04
Identities = 60/251 (23%), Positives = 79/251 (31%), Gaps = 27/251 (10%)
Query: 2100 TPHPAVNESFAHPSRAFSQPGTI--SRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTD 2157
TP P P+ + P T S PT+ P TP P + + + T +
Sbjct: 1398 TPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPT--TTPS 1455
Query: 2158 PYSQPPGTPRPTTV---DPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGI 2214
P TP PTT + P T PS T TP S P P P
Sbjct: 1456 PPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTT 1515
Query: 2215 SVPYSQPPATPRPRISEGFT-------RSSMTRPVLMPNQDPFLQAAQNRGP-----ALP 2262
++P P TP P + T T P+ P L P P
Sbjct: 1516 TLP---PTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTP 1572
Query: 2263 GPLVRPPDTCSQTPRPP-----GPGLSDTFSRVSPSAARDPYDQSPMTPRSQSDSFGTSQ 2317
P P + TP PP P + T S + + P +P P + + TS
Sbjct: 1573 PPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTST 1632
Query: 2318 TAHDVADQPRP 2328
T P P
Sbjct: 1633 TTLPPTTTPSP 1643
Score = 44.7 bits (104), Expect = 0.002
Identities = 34/113 (30%), Positives = 42/113 (37%), Gaps = 16/113 (14%)
Query: 3277 PPTMMPS----VQPQPPLIPGATPPTMSQPTFPMVPQQLQHQQHTTVISGHTSPVRMPSL 3332
PPT PS P PP I TPP + P+ P TT T+P +
Sbjct: 1573 PPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTT--------TTTPPPTTTPSPPTTT 1624
Query: 3333 PGWQPNSAPAHLPLNPPRIQPPIAQLPIKTCTPAPGTVSNANP----QSGPPP 3381
P P S P P P P T TP+P T + +P + PPP
Sbjct: 1625 PITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPP 1677
Score = 44.3 bits (103), Expect = 0.003
Identities = 72/293 (24%), Positives = 106/293 (36%), Gaps = 60/293 (20%)
Query: 1797 SGSDTPSSG---IQSPLTPQPG-NGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQA 1852
+G+ TP++ + +TP P G +P + T P TPT T +
Sbjct: 4145 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTG-------- 4196
Query: 1853 PPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPP---------SPMDPYAKMVG 1903
PP S PI ++ TS PP P+ +P +S S S + P +M
Sbjct: 4197 --PPTHTSTAPI----AELTTSNPP-PESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 4249
Query: 1904 TPRP----PPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTN 1959
T P P S S P +P + +R ++A PS V+ +S+ T
Sbjct: 4250 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWT- 4308
Query: 1960 NDPYAKPPDTPRPVMTDQFPKSLGLSRSP------VVSEQTAKGP------IAAGTSDHF 2007
TP P+ T ++ GL P V T P G + +F
Sbjct: 4309 --------PTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYF 4360
Query: 2008 TKPSPRADV-FQRQRIPDSYARPLLTPAPLDSGPGPFK---TPMQPPPSSQDP 2056
S + F P + P TP P S P P K TP +P P ++ P
Sbjct: 4361 VNCSLSCTLEFYNWSCPST---PSPTPTPSKSTPTPSKPSSTPSKPTPGTKPP 4410
Score = 43.5 bits (101), Expect = 0.005
Identities = 32/109 (29%), Positives = 41/109 (37%), Gaps = 9/109 (8%)
Query: 3277 PPTMMPSVQPQPPLIPGATPPTMSQPTFPMVPQQLQHQQHTTVISGHTSPVRMPSLPGWQ 3336
PPT PS P+ P A+ T+ T P P TT T+P + P
Sbjct: 1495 PPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTT-----TTTPPPTTTPSPPTTTPITP 1549
Query: 3337 PNSAPAHLPLNPPRIQPPIAQLPIKTCTPAPGTVSNANP----QSGPPP 3381
P S P P P P T TP+P T + +P + PPP
Sbjct: 1550 PTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPP 1598
Score = 40.0 bits (92), Expect = 0.057
Identities = 31/105 (29%), Positives = 38/105 (36%), Gaps = 10/105 (9%)
Query: 3279 TMMPSVQPQPPLIPGATPPTMSQP----TFPMVPQQLQHQQHTTVISGHTSPVRMPSLPG 3334
T P+ P PP+ TPP + P T P P TT + P PS P
Sbjct: 1447 TPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTT--PPPTTTPSPPT 1504
Query: 3335 WQPNSAPAHLPLNPPRIQPP----IAQLPIKTCTPAPGTVSNANP 3375
P + PA PP P P T TP+P T + P
Sbjct: 1505 TTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP 1549
Score = 38.9 bits (89), Expect = 0.13
Identities = 29/109 (26%), Positives = 41/109 (37%), Gaps = 10/109 (9%)
Query: 3279 TMMPSVQPQPPLIPGATPPTMSQPTFPMVPQQLQHQQHTTVISGHTSPVRMPSLPGWQPN 3338
T+ P+ P PP TPP + P+ P T+ + P PS P
Sbjct: 1555 TLPPTTTPSPPPTTTTTPPPTTTPS----PPTTTTPSPPTITTTTPPPTTTPSPPTTTTT 1610
Query: 3339 SAPAHLPLNPPR---IQPPIAQL---PIKTCTPAPGTVSNANPQSGPPP 3381
+ P +PP I PP + P T +P P T + P + P P
Sbjct: 1611 TPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSP 1659
Score = 37.0 bits (84), Expect = 0.48
Identities = 28/99 (28%), Positives = 37/99 (37%), Gaps = 11/99 (11%)
Query: 3277 PPTMMPS----VQPQPPLIPGATPPTMSQPTFPMVPQQLQHQQHTTVISGHTSPVRMPSL 3332
PPT PS P PP+ TPP + P+ P+ T SP PS
Sbjct: 1652 PPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTT----PSPPTTTMTTPSPTTTPSS 1707
Query: 3333 PGWQPNSAPAHLPLNPPRIQPPIAQLPIKTCTPAPGTVS 3371
P + + +PP P P T TP+P T +
Sbjct: 1708 PITTTTTPSSTTTPSPP---PTTMTTPSPTTTPSPPTTT 1743
Score = 36.2 bits (82), Expect = 0.82
Identities = 62/287 (21%), Positives = 87/287 (30%), Gaps = 41/287 (14%)
Query: 3897 PPTPPASLPPTPPPMACQKMANGFATTEELAGKAGVLVSHEVTKTLGPKPFQLPFRPQDD 3956
PPT +LPPT P T + S T P P P P
Sbjct: 1549 PPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTT- 1607
Query: 3957 LLARALAQGPKTVDVPASLPTPPHNNQEELRIQDHCGDRDTPDSFVPSSSPESVVGVEVS 4016
T P + P+PP I P + PS P +
Sbjct: 1608 ---------TTTTPPPTTTPSPPTTTP----ITPPTSTTTLPPTTTPSPPPTTTT----- 1649
Query: 4017 RYPDLSLVKEEPPEPVPSPIIPILPSTAGKSSESRRNDIKTEPGTLYFASPFGPSPNGPR 4076
PP PSP PS ++ T P T +SP +P+ P
Sbjct: 1650 ---------TPPPTTTPSPPTTTTPSPPITTT-------TTPPPTTTPSSPITTTPSPPT 1693
Query: 4077 SGLISVAITLHPTAAENISSVVAAFSDLLHVRIPNSYEVSSAPDVPSMGLVSSHRINPGL 4136
+ + + + T P++ I++ S P + S PS + + P
Sbjct: 1694 TTMTTPSPTTTPSSP--ITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPP-- 1749
Query: 4137 EYRQHLLLRGPPPGSANPPRLVSSYRLKQPNVPFPPTSNGLSGYKDS 4183
L P P S PP S + P P P N +G+ DS
Sbjct: 1750 TTTSSPLTTTPLPPSITPPTF-SPFSTTTPTTPCVPLCN-WTGWLDS 1794
Score = 35.0 bits (79), Expect = 1.8
Identities = 24/97 (24%), Positives = 35/97 (36%), Gaps = 1/97 (1%)
Query: 3279 TMMPSVQPQPPLIPGATPPTMSQPTFPMVPQQLQHQQHTTVISGHTSPVRMPSLPGWQPN 3338
T+ P+ P PP TPP + P+ P+ T T+ P+ P
Sbjct: 1415 TLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPT 1474
Query: 3339 SAPAHLPLNPPRIQPPIAQLPIKTCTPAPGTVSNANP 3375
+ P+ P P P T TP+P T + P
Sbjct: 1475 TTPSP-PTTTPSPPTTTTTTPPPTTTPSPPTTTPITP 1510
Score = 34.3 bits (77), Expect = 3.1
Identities = 51/230 (22%), Positives = 77/230 (33%), Gaps = 23/230 (10%)
Query: 3496 PSTQTFMQTNERRQVGPPSFVPDSPSI-PVGSPNFSSVKQGHGNLSGTSFQQSPVRPSFT 3554
P T T PP+ P P+ P+ P ++ S + P+ T
Sbjct: 1518 PPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTT 1577
Query: 3555 PALPA----APPVANSSLP----CGQDSTITHGHSYPGSTQSLIQLYSDIIPEEKGKKKR 3606
P+ P +PP ++ P T T P +T S P
Sbjct: 1578 PSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPP 1637
Query: 3607 TRKKKRDDDAESTKAPST-PHSDITAPPTPGISETTSTPAVSTPSELPQQADQESVEPVG 3665
T +T P+T P T P+P I+ TT+ P +TPS P+
Sbjct: 1638 TTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPS-----------SPI- 1685
Query: 3666 PSTPNMAAGQLCTELENKLPNSDFSQATPNQQTYANSEVDKLSMETPAKT 3715
+TP+ + T P+S + T T S +M TP+ T
Sbjct: 1686 TTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSP-PPTTMTTPSPT 1734
Score = 33.1 bits (74), Expect = 7.0
Identities = 34/128 (26%), Positives = 47/128 (36%), Gaps = 26/128 (20%)
Query: 3261 LIEDYRIK-----QQQQCAMAPPTMMPSVQPQPPLIPGATPPTMSQPTFPMVPQQLQHQQ 3315
L DY+I+ +C P P+ P PP T P + P+ P
Sbjct: 1378 LCYDYKIRVNCCWPMDKCITTPSP--PTTTPSPPPTSTTTLPPTTTPSPP---------- 1425
Query: 3316 HTTVISGHTSPVRMPSLPGWQPNSAPAHLPLNPPRIQPPIAQL--PIKTCTPAPGTVSNA 3373
T + P PS P + P P P PPI+ P T TP+P T + +
Sbjct: 1426 --TTTTTTPPPTTTPSPPITTTTTPP---PTTTP--SPPISTTTTPPPTTTPSPPTTTPS 1478
Query: 3374 NPQSGPPP 3381
P + P P
Sbjct: 1479 PPTTTPSP 1486
Score = 33.1 bits (74), Expect = 7.0
Identities = 39/158 (24%), Positives = 51/158 (32%), Gaps = 20/158 (12%)
Query: 3895 SNPPTPPASLPPTPPPMACQKMANGFATTEELAGKAGVLVSHEVTKTLGPKPFQLPFRPQ 3954
S PPT +LPPT P TT S +T T P P P P
Sbjct: 1407 SPPPTSTTTLPPTTTPSP--------PTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPP- 1457
Query: 3955 DDLLARALAQGPKTV-DVPASLPTPPHNNQEELRIQDHCGDRDT---PDSFVPSSSPESV 4010
++ P T P + P+PP T P + P + P S
Sbjct: 1458 ---ISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPAST 1514
Query: 4011 VGV--EVSRYPDLSLVKEEPPEPVPSP--IIPILPSTA 4044
+ + P + PP PSP PI P T+
Sbjct: 1515 TTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTS 1552
Score = 32.7 bits (73), Expect = 9.1
Identities = 34/114 (29%), Positives = 40/114 (35%), Gaps = 18/114 (15%)
Query: 3277 PPTMMPS----VQPQPPLIPGATPPTMSQPTFPMVPQQLQHQQHT--------TVISGHT 3324
PPT PS P PP TP + P+ P+ T T S T
Sbjct: 1676 PPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTT 1735
Query: 3325 SP----VRMPSLPGWQPNSAPAHLPLNPPRIQPPIAQLPIKTCTPAPGTVSNAN 3374
+P M +LP +S PL PP I PP P T TP V N
Sbjct: 1736 TPSPPTTTMTTLPPTTTSSPLTTTPL-PPSITPPTFS-PFSTTTPTTPCVPLCN 1787
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 85.5 bits (210), Expect = 1e-15
Identities = 138/567 (24%), Positives = 205/567 (36%), Gaps = 96/567 (16%)
Query: 1987 SPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDSGPGPFKTP 2046
+P V++Q I+ S+ P ++ + RP +P+ LDS G
Sbjct: 64 TPKVNKQGRSEEISESESEETNAP-------KKTKTEQELPRPQ-SPSDLDSLDGRSLND 115
Query: 2047 MQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSN------DPYSQPPL- 2099
S DP + Q +R S Y +P ++N S + S PY PPL
Sbjct: 116 ----DGSSDPR-DIDQDNRSTSPSIY-----SPGSVENDSDSSSGLSQGPARPYHPPPLF 165
Query: 2100 TPHPAVNESFAHPSRAFSQPGTISRPTS-----QDPYSQ----PPGTPRPVVDSYSQSSG 2150
P P +S A +P PT + P S+ PPG P P Y +G
Sbjct: 166 PPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTG 225
Query: 2151 TARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTP 2210
S P P G ++V + Q P P+T ++ ++ P PP TP
Sbjct: 226 GVLSG--PPMGPKGGGAASSVGGPNGGKQHPPPTTP----ISVSSSGASGAPPTKPPTTP 279
Query: 2211 RPGISVPYSQPPAT--------PRPRISEGFTRSSMTRPVL----MPNQDPFLQA-AQNR 2257
G ++P + PPA P P +S + P L +P P A Q
Sbjct: 280 VGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGM 339
Query: 2258 GPALPGPLVRP---------PDTCSQTPRPP---------GPGLSDTFSRVSPSAARDPY 2299
G PGP P P S P PP + + S S S++ P+
Sbjct: 340 GGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPF 399
Query: 2300 DQSPMTPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASS-----NSPMHSQGQQFSGVSQ 2354
S P S SF T+ V++QP ++ S + + P G+ + +
Sbjct: 400 PASQALP-SYPHSF-PPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNA 457
Query: 2355 LPGPVPTSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKKIAGRQEKGSQDSPAV 2414
PGP P S T Q+T + + Q+Q+ ++ QQQQQ++ G A
Sbjct: 458 HPGPFPPS--TGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAF 515
Query: 2415 PHP---GPLQHWQPENVNQAF--TRPPPPYPGNI-----------RSPVAPPLGPRYAVF 2458
PHP G H P ++ + RP PP P ++ P PP+
Sbjct: 516 PHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSS 575
Query: 2459 PKDQRGPYPPDVASMGMRPHGFRFGFP 2485
+G YP S P G + FP
Sbjct: 576 SSTSQGSYPCSHPSPSQGPQGAPYPFP 602
Score = 81.6 bits (200), Expect = 2e-14
Identities = 167/702 (23%), Positives = 246/702 (35%), Gaps = 107/702 (15%)
Query: 1834 PPSTPTSTSSDDVFVKPQAPPPP-----------PAPSRIP-IQDSLSQAQTSQPPSPQV 1881
PP+TP S SS P PP P P+ P + +L +P +
Sbjct: 255 PPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNAS 314
Query: 1882 FSPGSSNSRP-----PSPMDPYAKMVGTPRPPPVGHSFSRR-NSAAPVENCTPLSSVSRP 1935
SP ++P PSP M G P P G + + +S P + P + P
Sbjct: 315 ASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFP 374
Query: 1936 LQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTA 1995
+ +++ S SSS+++ P+ P P FP LS VS Q
Sbjct: 375 YSSSSSSSAAAS---SSSSSSSSSASPF--PASQALPSYPHSFPPPTSLS----VSNQPP 425
Query: 1996 KGPIAAGTSDHFTKPS-PRADVF-QRQRIPDSYARPLLTPAPLDSGPGPF------KTPM 2047
K +T+PS P V+ Q P Y R L A ++ PGPF ++
Sbjct: 426 K----------YTQPSLPSQAVWSQGPPPPPPYGRLL---ANSNAHPGPFPPSTGAQSTA 472
Query: 2048 QPPPSSQDPYGSVSQASRRLSVDPYER------------PALTPRPIDNFSHNQSNDPYS 2095
PP S+ + Q ++ ++ P P P++ S + ++ PY+
Sbjct: 473 HPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAH-PYA 531
Query: 2096 QPP----LTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGT 2151
P L P+P P + P SQ YSQ G P V S S SS +
Sbjct: 532 MSPSLGSLRPYPP-------------GPAHLPPPHSQVSYSQA-GPNGPPVSSSSNSSSS 577
Query: 2152 ARSNTDPYSQPPGTPRPTTVD-PYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTP 2210
+ P S P + P P+ P S + V + A PPG P
Sbjct: 578 TSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPP 637
Query: 2211 RPGISVPY--SQPPATPRPRISEGFTRS--SMTRPVLMPNQDPFLQAAQNRGPALPGPLV 2266
G P + ATP P G S + T P P G GP
Sbjct: 638 PYGKRAPSPGAYKTATP-PGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGP 696
Query: 2267 RPPDTCSQTPR-PPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQSDSFGTSQTAHDVADQ 2325
PP S P PP P + +S + + + TP S + V D
Sbjct: 697 LPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDV 756
Query: 2326 PRPGSEGS-FCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQNTVNMA---QADTEKL 2381
P S+ + F + +S + L G D V +A EK
Sbjct: 757 PSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKE 816
Query: 2382 RQRQKLREIILQQQQQKKIAGRQEKGSQDSPA---VPHPGPLQHWQPENVNQAFTRPPPP 2438
R+R++ RE ++++++++ R K +Q+ A P GP+ H PP
Sbjct: 817 REREREREKEREREKERELE-RSVKLAQEGRAPVECPSLGPVPH------------RPPF 863
Query: 2439 YPGNIRSPVAPPLGPRYAVFPKDQRGPYPPDVASMGMRPHGF 2480
PG+ + V P LGP + P V S G R H F
Sbjct: 864 EPGSAVATVPPYLGPDTPAL-RTLSEYARPHVMSPGNRNHPF 904
Score = 76.3 bits (186), Expect = 7e-13
Identities = 165/700 (23%), Positives = 237/700 (33%), Gaps = 104/700 (14%)
Query: 1728 SSRIDSELFKDPLKQRESEHEQEWKFRQQMRQKSKQQAKIEATQKLEQVKNEQQQQQQQQ 1787
SS +E + K+ E K +Q R + +++ E T ++ K EQ+ + Q
Sbjct: 42 SSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQS 101
Query: 1788 FGSQHLLVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVF 1847
L G G P N + SP+ + S+ S
Sbjct: 102 PSDLDSL--DGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGP---- 155
Query: 1848 VKPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRP 1907
+P PPP PS P + Q + S P P V G P P ++M P
Sbjct: 156 ARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEP----PTSRMFQAPPG 211
Query: 1908 PPVGHSFSRRNSAAPVENCTPL--------SSVSRPLQMNETTANRPSPVRDLCSSSTTN 1959
P H V + P+ SSV P N + P SSS +
Sbjct: 212 APPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGP---NGGKQHPPPTTPISVSSSGAS 268
Query: 1960 NDPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQR 2019
P KPP T PV P + + P V+ P ++ P
Sbjct: 269 GAPPTKPPTT--PVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASP--------- 317
Query: 2020 QRIPDSYARPL--LTPAPLDSG-------PGPFKTP-MQPPPSSQDPYGSVSQASRRLSV 2069
P A+PL P+P G PGP K P + P P S P S + A
Sbjct: 318 ---PGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRF- 373
Query: 2070 DPYERPALTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPS--RAFSQPGTISRPT- 2126
PY + + + S + S+ P P+ SF P+ +QP ++P+
Sbjct: 374 -PYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSL 432
Query: 2127 -SQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDP--------YSQQ 2177
SQ +SQ P P P Y + A SN P PP T +T P + QQ
Sbjct: 433 PSQAVWSQGPPPPPP----YGRL--LANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQ 486
Query: 2178 PQTPRPSTQTD----------------LFVTPVT--NQRHSDPYAHPPGTPRPGISVPYS 2219
Q + Q F P+ + H+ PYA P G PY
Sbjct: 487 QQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSL---GSLRPYP 543
Query: 2220 QPPA-TPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRGP-ALPGPLVRPPDTCSQTPR 2277
PA P P ++++ P + + + +Q P + P P P + P
Sbjct: 544 PGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQG--APYPF 601
Query: 2278 PPGPGL---SDTFSRVSPSAARDPYDQSPMTPRSQS--DSFGTSQTAHDVADQP--RPGS 2330
PP P + S T S V + A P +P S A+ A P +PGS
Sbjct: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS 661
Query: 2331 EGSFCASS------NSPMHSQGQQFSGVSQL-PGPVPTSG 2363
SF + SP G G + PGP+P +G
Sbjct: 662 PPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAG 701
Score = 43.5 bits (101), Expect = 0.005
Identities = 85/414 (20%), Positives = 130/414 (31%), Gaps = 42/414 (10%)
Query: 3278 PTMMPSVQPQPPLIPGATPPTMSQPTFPMVPQQLQHQQHTTVISGHTSPV----RMPSLP 3333
PT+ PS PP A P M P ++ S SP +PS P
Sbjct: 350 PTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYP 409
Query: 3334 GWQPNSAPAHLPLNPPRI-QPPIAQLPIKTCTPAPGTV-------SNANPQSGPPPRVEF 3385
P + PP+ QP + + + P P SNA+P PP
Sbjct: 410 HSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQ 469
Query: 3386 DDNNPFSESFQERERKERLREQQERQRIQLMQEVDRQRALQQRMEMEQHGMVGSEISSSR 3445
+P + ++++ ++QQ++Q QQ+ + + HG G +
Sbjct: 470 STAHPPVSTHHHHHQQQQQQQQQQQQ--------------QQQQQQQHHGNSGPPPPGAF 515
Query: 3446 TSVSQIPFYSSDLPCDFMQPLGPLQQSPQHQQQMGQVLQQQNIQQGSINSPSTQTFMQTN 3505
+ P LG L+ P + Q + Q N P + ++
Sbjct: 516 PHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSS 575
Query: 3506 ERRQVGPPSFVPDSPS-----IPVGSPNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAA 3560
G SPS P P +V LS + + A P
Sbjct: 576 SSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPG 635
Query: 3561 PPVANSSLPC-GQDSTITHGHSYPGSTQSLIQLYSDIIPEEKGKK----KRTRKKKRDDD 3615
PP P G T T PGS S + P +G T K
Sbjct: 636 PPPYGKRAPSPGAYKTATPPGYKPGSPPS---FRTGTPPGYRGTSPPAGPGTFKPGSPTV 692
Query: 3616 AESTKAPSTPHSDITAPPTPGISETTSTPAVSTPSELPQQADQESVEPVGPSTP 3669
P+ P + PP P + S P +S +++ Q+ +E P P P
Sbjct: 693 GPGPLPPAGPSGLPSLPPPP--AAPASGPPLSA-TQIKQEPAEEYETPESPVPP 743
Score = 40.0 bits (92), Expect = 0.057
Identities = 104/469 (22%), Positives = 147/469 (31%), Gaps = 106/469 (22%)
Query: 3470 QQSPQHQQQMGQVLQQQNIQQGSINSPSTQTF---MQTNERRQVGPPSFVPDSPSIPVGS 3526
QQ Q QQQ Q QQQ G+ P F ++ P + P S+
Sbjct: 484 QQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYP 543
Query: 3527 PNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAAPPVANSSLPCGQDSTI--THGHSYP- 3583
P + + H +S + Q P P + + ++ + S PC S G YP
Sbjct: 544 PGPAHLPPPHSQVSYS--QAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPF 601
Query: 3584 -------GSTQSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTKAPSTPHSDITAPPTPG 3636
S+ +L + + + G K T +P P P+PG
Sbjct: 602 PPVPTVTTSSATLSTVIATVASSPAGYK--------------TASPPGPPPYGKRAPSPG 647
Query: 3637 ISETTSTPAVSTPSELPQ------QADQESVEPVGPST-----PNMAAGQLCTELENKLP 3685
+ T+TP P P + + P GP T P + G L + LP
Sbjct: 648 -AYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLP 706
Query: 3686 NSDFSQATPNQQTYANSEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVE 3745
+ A P + P +IK E AE P P
Sbjct: 707 SLPPPPAAP-------------ASGPPLSATQIKQEPAEEYETPESPVP----------- 742
Query: 3746 GNAVACPVSSAQSPPHSAGAPAAKGDSGNELLKHLLKNKKS---SSLLNQKPEGSICSED 3802
P S PP P+ S KHL + S S L EGS ++
Sbjct: 743 ------PARSPSPPPKVVDVPSHASQSA-RFNKHLDRGFNSCARSDLYFVPLEGSKLAK- 794
Query: 3803 DCTKDNKLVEK-QNPAEGLQTLGAQMQGGFGCGNQLPKTDGGSETKKQRSKRTQRTGEKA 3861
K LVEK + AE Q + + E +++R K +R E+
Sbjct: 795 ---KRADLVEKVRREAE-----------------QRAREEKEREREREREKEREREKERE 834
Query: 3862 APRSKKRKKDEEEKQAMYSSTDTFTHLKQQNNLSNPPTPPASLPPTPPP 3910
RS K + E S H PP P S T PP
Sbjct: 835 LERSVKLAQ-EGRAPVECPSLGPVPH--------RPPFEPGSAVATVPP 874
Score = 37.4 bits (85), Expect = 0.37
Identities = 45/164 (27%), Positives = 65/164 (39%), Gaps = 24/164 (14%)
Query: 3236 HVTEQQSMVQKQLEQIRKQQKEH------------AELIEDYRIKQQQQCAMAPPTMMPS 3283
H +QQ Q+Q +Q ++QQ++H +E AM+P + S
Sbjct: 481 HHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSP--SLGS 538
Query: 3284 VQPQPPLIPGATPPTMSQPTF----PMVPQQLQHQQHTTVISGHTSPVRMPSLPGWQPNS 3339
++P PP P PP SQ ++ P P ++ S + P PS P P
Sbjct: 539 LRPYPP-GPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPS-PSQGPQG 596
Query: 3340 APAHLPLNPPRIQPPIAQLP--IKTCTPAPGTVSNANPQSGPPP 3381
AP P P + A L I T +P A+P GPPP
Sbjct: 597 APYPFP-PVPTVTTSSATLSTVIATVASSPAGYKTASP-PGPPP 638
Score = 37.0 bits (84), Expect = 0.48
Identities = 40/129 (31%), Positives = 53/129 (41%), Gaps = 29/129 (22%)
Query: 3276 APPTMMPSVQPQPPLIPGATPPTMSQPTFPMVPQQ-------------LQHQQHTTVISG 3322
APP P P P L PG T +S P PM P+ QH TT IS
Sbjct: 208 APPGAPP---PHPQLYPGGTGGVLSGP--PMGPKGGGAASSVGGPNGGKQHPPPTTPISV 262
Query: 3323 HTS------PVRMPSLP---GWQPNSAP-AHLPLNPPRIQPPIAQLPIKTCTPAPGTVSN 3372
+S P + P+ P G P++ P A+ P P + PP A P+ + +P +
Sbjct: 263 SSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGL-G 321
Query: 3373 ANPQSGPPP 3381
A P G P
Sbjct: 322 AQPLPGHLP 330
Score = 34.3 bits (77), Expect = 3.1
Identities = 63/285 (22%), Positives = 92/285 (32%), Gaps = 69/285 (24%)
Query: 2415 PHPG--PLQHWQPEN--VNQAFTRPP---PP----YPGNIRSPVA-PPLGPRYAVFPKDQ 2462
PHP P + P ++ F PP PP YPG ++ PP+GP+
Sbjct: 185 PHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSV 244
Query: 2463 RGP-----YPPDVASMGMRPHGFRFGFPGGSHGTMPSQERFLVPPQQIQGSGVSPQLRRS 2517
GP +PP + + G+ G P++ PP G G P
Sbjct: 245 GGPNGGKQHPPPTTPISVSS--------SGASGAPPTK-----PPTTPVGGGNLPSAPPP 291
Query: 2518 -----VSVDMPRPLNNSQMNNPVGLPQHFSPQSLP--VQQHNILGQAYIEL--------- 2561
V+ ++P P +NN P Q LP + + +GQ L
Sbjct: 292 ANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPT 351
Query: 2562 -----------RHRAPDGRQRLPFSAPPGSVVEASSNLRHGNFIPRP------------D 2598
AP R P+S+ S ASS+ + P
Sbjct: 352 LAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHS 411
Query: 2599 FPGPRHTDPMRRPPQGLPNQLPVHPDLEQVPPSQQEQGHSVHSSS 2643
FP P +PP+ LP Q PP G + +S+
Sbjct: 412 FPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSN 456
Score = 33.9 bits (76), Expect = 4.1
Identities = 53/212 (25%), Positives = 73/212 (34%), Gaps = 25/212 (11%)
Query: 3972 PASLPTPPHNNQEELRIQDHCGDRDTPDSFVPSSSPESVVGVEVSRYPDLSLVKEEPPEP 4031
PA LP PPH+ G P S +SS + G +P S + P P
Sbjct: 546 PAHLP-PPHSQVS----YSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYP 600
Query: 4032 VPSPIIPILPSTAGKSSESRRNDIKTEPGTLYFASPFGPSPNGPRSGLISVAITLHPTAA 4091
P P+ + S+A S+ + + P ASP GP P G R+ T P
Sbjct: 601 FP-PVPTVTTSSATLSTVIAT--VASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGY 657
Query: 4092 ENISSVVAAFSDLLHVRIPNSYEVSSAPDVPSMGLVSSHRINPG---LEYRQHLLLRGPP 4148
+ S P Y +S P P S + PG L PP
Sbjct: 658 KPGS------PPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPP 711
Query: 4149 PGSANPPRLVSSYRLKQ--------PNVPFPP 4172
P + +S+ ++KQ P P PP
Sbjct: 712 PAAPASGPPLSATQIKQEPAEEYETPESPVPP 743
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 85.5 bits (210), Expect = 1e-15
Identities = 138/567 (24%), Positives = 205/567 (36%), Gaps = 96/567 (16%)
Query: 1987 SPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDSGPGPFKTP 2046
+P V++Q I+ S+ P ++ + RP +P+ LDS G
Sbjct: 64 TPKVNKQGRSEEISESESEETNAP-------KKTKTEQELPRPQ-SPSDLDSLDGRSLND 115
Query: 2047 MQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSN------DPYSQPPL- 2099
S DP + Q +R S Y +P ++N S + S PY PPL
Sbjct: 116 ----DGSSDPR-DIDQDNRSTSPSIY-----SPGSVENDSDSSSGLSQGPARPYHPPPLF 165
Query: 2100 TPHPAVNESFAHPSRAFSQPGTISRPTS-----QDPYSQ----PPGTPRPVVDSYSQSSG 2150
P P +S A +P PT + P S+ PPG P P Y +G
Sbjct: 166 PPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTG 225
Query: 2151 TARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTP 2210
S P P G ++V + Q P P+T ++ ++ P PP TP
Sbjct: 226 GVLSG--PPMGPKGGGAASSVGGPNGGKQHPPPTTP----ISVSSSGASGAPPTKPPTTP 279
Query: 2211 RPGISVPYSQPPAT--------PRPRISEGFTRSSMTRPVL----MPNQDPFLQA-AQNR 2257
G ++P + PPA P P +S + P L +P P A Q
Sbjct: 280 VGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGM 339
Query: 2258 GPALPGPLVRP---------PDTCSQTPRPP---------GPGLSDTFSRVSPSAARDPY 2299
G PGP P P S P PP + + S S S++ P+
Sbjct: 340 GGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPF 399
Query: 2300 DQSPMTPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASS-----NSPMHSQGQQFSGVSQ 2354
S P S SF T+ V++QP ++ S + + P G+ + +
Sbjct: 400 PASQALP-SYPHSF-PPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNA 457
Query: 2355 LPGPVPTSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKKIAGRQEKGSQDSPAV 2414
PGP P S T Q+T + + Q+Q+ ++ QQQQQ++ G A
Sbjct: 458 HPGPFPPS--TGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAF 515
Query: 2415 PHP---GPLQHWQPENVNQAF--TRPPPPYPGNI-----------RSPVAPPLGPRYAVF 2458
PHP G H P ++ + RP PP P ++ P PP+
Sbjct: 516 PHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSS 575
Query: 2459 PKDQRGPYPPDVASMGMRPHGFRFGFP 2485
+G YP S P G + FP
Sbjct: 576 SSTSQGSYPCSHPSPSQGPQGAPYPFP 602
Score = 81.6 bits (200), Expect = 2e-14
Identities = 167/702 (23%), Positives = 246/702 (35%), Gaps = 107/702 (15%)
Query: 1834 PPSTPTSTSSDDVFVKPQAPPPP-----------PAPSRIP-IQDSLSQAQTSQPPSPQV 1881
PP+TP S SS P PP P P+ P + +L +P +
Sbjct: 255 PPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNAS 314
Query: 1882 FSPGSSNSRP-----PSPMDPYAKMVGTPRPPPVGHSFSRR-NSAAPVENCTPLSSVSRP 1935
SP ++P PSP M G P P G + + +S P + P + P
Sbjct: 315 ASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRFP 374
Query: 1936 LQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTA 1995
+ +++ S SSS+++ P+ P P FP LS VS Q
Sbjct: 375 YSSSSSSSAAAS---SSSSSSSSSASPF--PASQALPSYPHSFPPPTSLS----VSNQPP 425
Query: 1996 KGPIAAGTSDHFTKPS-PRADVF-QRQRIPDSYARPLLTPAPLDSGPGPF------KTPM 2047
K +T+PS P V+ Q P Y R L A ++ PGPF ++
Sbjct: 426 K----------YTQPSLPSQAVWSQGPPPPPPYGRLL---ANSNAHPGPFPPSTGAQSTA 472
Query: 2048 QPPPSSQDPYGSVSQASRRLSVDPYER------------PALTPRPIDNFSHNQSNDPYS 2095
PP S+ + Q ++ ++ P P P++ S + ++ PY+
Sbjct: 473 HPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAH-PYA 531
Query: 2096 QPP----LTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGT 2151
P L P+P P + P SQ YSQ G P V S S SS +
Sbjct: 532 MSPSLGSLRPYPP-------------GPAHLPPPHSQVSYSQA-GPNGPPVSSSSNSSSS 577
Query: 2152 ARSNTDPYSQPPGTPRPTTVD-PYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTP 2210
+ P S P + P P+ P S + V + A PPG P
Sbjct: 578 TSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPP 637
Query: 2211 RPGISVPY--SQPPATPRPRISEGFTRS--SMTRPVLMPNQDPFLQAAQNRGPALPGPLV 2266
G P + ATP P G S + T P P G GP
Sbjct: 638 PYGKRAPSPGAYKTATP-PGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGP 696
Query: 2267 RPPDTCSQTPR-PPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQSDSFGTSQTAHDVADQ 2325
PP S P PP P + +S + + + TP S + V D
Sbjct: 697 LPPAGPSGLPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARSPSPPPKVVDV 756
Query: 2326 PRPGSEGS-FCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQNTVNMA---QADTEKL 2381
P S+ + F + +S + L G D V +A EK
Sbjct: 757 PSHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKE 816
Query: 2382 RQRQKLREIILQQQQQKKIAGRQEKGSQDSPA---VPHPGPLQHWQPENVNQAFTRPPPP 2438
R+R++ RE ++++++++ R K +Q+ A P GP+ H PP
Sbjct: 817 REREREREKEREREKERELE-RSVKLAQEGRAPVECPSLGPVPH------------RPPF 863
Query: 2439 YPGNIRSPVAPPLGPRYAVFPKDQRGPYPPDVASMGMRPHGF 2480
PG+ + V P LGP + P V S G R H F
Sbjct: 864 EPGSAVATVPPYLGPDTPAL-RTLSEYARPHVMSPGNRNHPF 904
Score = 76.3 bits (186), Expect = 7e-13
Identities = 165/700 (23%), Positives = 237/700 (33%), Gaps = 104/700 (14%)
Query: 1728 SSRIDSELFKDPLKQRESEHEQEWKFRQQMRQKSKQQAKIEATQKLEQVKNEQQQQQQQQ 1787
SS +E + K+ E K +Q R + +++ E T ++ K EQ+ + Q
Sbjct: 42 SSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKTKTEQELPRPQS 101
Query: 1788 FGSQHLLVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVF 1847
L G G P N + SP+ + S+ S
Sbjct: 102 PSDLDSL--DGRSLNDDGSSDPRDIDQDNRSTSPSIYSPGSVENDSDSSSGLSQGP---- 155
Query: 1848 VKPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRP 1907
+P PPP PS P + Q + S P P V G P P ++M P
Sbjct: 156 ARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEP----PTSRMFQAPPG 211
Query: 1908 PPVGHSFSRRNSAAPVENCTPL--------SSVSRPLQMNETTANRPSPVRDLCSSSTTN 1959
P H V + P+ SSV P N + P SSS +
Sbjct: 212 APPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGP---NGGKQHPPPTTPISVSSSGAS 268
Query: 1960 NDPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQR 2019
P KPP T PV P + + P V+ P ++ P
Sbjct: 269 GAPPTKPPTT--PVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASP--------- 317
Query: 2020 QRIPDSYARPL--LTPAPLDSG-------PGPFKTP-MQPPPSSQDPYGSVSQASRRLSV 2069
P A+PL P+P G PGP K P + P P S P S + A
Sbjct: 318 ---PGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPPMRF- 373
Query: 2070 DPYERPALTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPS--RAFSQPGTISRPT- 2126
PY + + + S + S+ P P+ SF P+ +QP ++P+
Sbjct: 374 -PYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSL 432
Query: 2127 -SQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDP--------YSQQ 2177
SQ +SQ P P P Y + A SN P PP T +T P + QQ
Sbjct: 433 PSQAVWSQGPPPPPP----YGRL--LANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQ 486
Query: 2178 PQTPRPSTQTD----------------LFVTPVT--NQRHSDPYAHPPGTPRPGISVPYS 2219
Q + Q F P+ + H+ PYA P G PY
Sbjct: 487 QQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSL---GSLRPYP 543
Query: 2220 QPPA-TPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRGP-ALPGPLVRPPDTCSQTPR 2277
PA P P ++++ P + + + +Q P + P P P + P
Sbjct: 544 PGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQG--APYPF 601
Query: 2278 PPGPGL---SDTFSRVSPSAARDPYDQSPMTPRSQS--DSFGTSQTAHDVADQP--RPGS 2330
PP P + S T S V + A P +P S A+ A P +PGS
Sbjct: 602 PPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGS 661
Query: 2331 EGSFCASS------NSPMHSQGQQFSGVSQL-PGPVPTSG 2363
SF + SP G G + PGP+P +G
Sbjct: 662 PPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAG 701
Score = 43.5 bits (101), Expect = 0.005
Identities = 85/414 (20%), Positives = 130/414 (31%), Gaps = 42/414 (10%)
Query: 3278 PTMMPSVQPQPPLIPGATPPTMSQPTFPMVPQQLQHQQHTTVISGHTSPV----RMPSLP 3333
PT+ PS PP A P M P ++ S SP +PS P
Sbjct: 350 PTLAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYP 409
Query: 3334 GWQPNSAPAHLPLNPPRI-QPPIAQLPIKTCTPAPGTV-------SNANPQSGPPPRVEF 3385
P + PP+ QP + + + P P SNA+P PP
Sbjct: 410 HSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQ 469
Query: 3386 DDNNPFSESFQERERKERLREQQERQRIQLMQEVDRQRALQQRMEMEQHGMVGSEISSSR 3445
+P + ++++ ++QQ++Q QQ+ + + HG G +
Sbjct: 470 STAHPPVSTHHHHHQQQQQQQQQQQQ--------------QQQQQQQHHGNSGPPPPGAF 515
Query: 3446 TSVSQIPFYSSDLPCDFMQPLGPLQQSPQHQQQMGQVLQQQNIQQGSINSPSTQTFMQTN 3505
+ P LG L+ P + Q + Q N P + ++
Sbjct: 516 PHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSS 575
Query: 3506 ERRQVGPPSFVPDSPS-----IPVGSPNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAA 3560
G SPS P P +V LS + + A P
Sbjct: 576 SSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPG 635
Query: 3561 PPVANSSLPC-GQDSTITHGHSYPGSTQSLIQLYSDIIPEEKGKK----KRTRKKKRDDD 3615
PP P G T T PGS S + P +G T K
Sbjct: 636 PPPYGKRAPSPGAYKTATPPGYKPGSPPS---FRTGTPPGYRGTSPPAGPGTFKPGSPTV 692
Query: 3616 AESTKAPSTPHSDITAPPTPGISETTSTPAVSTPSELPQQADQESVEPVGPSTP 3669
P+ P + PP P + S P +S +++ Q+ +E P P P
Sbjct: 693 GPGPLPPAGPSGLPSLPPPP--AAPASGPPLSA-TQIKQEPAEEYETPESPVPP 743
Score = 40.0 bits (92), Expect = 0.057
Identities = 104/469 (22%), Positives = 147/469 (31%), Gaps = 106/469 (22%)
Query: 3470 QQSPQHQQQMGQVLQQQNIQQGSINSPSTQTF---MQTNERRQVGPPSFVPDSPSIPVGS 3526
QQ Q QQQ Q QQQ G+ P F ++ P + P S+
Sbjct: 484 QQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYP 543
Query: 3527 PNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAAPPVANSSLPCGQDSTI--THGHSYP- 3583
P + + H +S + Q P P + + ++ + S PC S G YP
Sbjct: 544 PGPAHLPPPHSQVSYS--QAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPF 601
Query: 3584 -------GSTQSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTKAPSTPHSDITAPPTPG 3636
S+ +L + + + G K T +P P P+PG
Sbjct: 602 PPVPTVTTSSATLSTVIATVASSPAGYK--------------TASPPGPPPYGKRAPSPG 647
Query: 3637 ISETTSTPAVSTPSELPQ------QADQESVEPVGPST-----PNMAAGQLCTELENKLP 3685
+ T+TP P P + + P GP T P + G L + LP
Sbjct: 648 -AYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLP 706
Query: 3686 NSDFSQATPNQQTYANSEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVE 3745
+ A P + P +IK E AE P P
Sbjct: 707 SLPPPPAAP-------------ASGPPLSATQIKQEPAEEYETPESPVP----------- 742
Query: 3746 GNAVACPVSSAQSPPHSAGAPAAKGDSGNELLKHLLKNKKS---SSLLNQKPEGSICSED 3802
P S PP P+ S KHL + S S L EGS ++
Sbjct: 743 ------PARSPSPPPKVVDVPSHASQSA-RFNKHLDRGFNSCARSDLYFVPLEGSKLAK- 794
Query: 3803 DCTKDNKLVEK-QNPAEGLQTLGAQMQGGFGCGNQLPKTDGGSETKKQRSKRTQRTGEKA 3861
K LVEK + AE Q + + E +++R K +R E+
Sbjct: 795 ---KRADLVEKVRREAE-----------------QRAREEKEREREREREKEREREKERE 834
Query: 3862 APRSKKRKKDEEEKQAMYSSTDTFTHLKQQNNLSNPPTPPASLPPTPPP 3910
RS K + E S H PP P S T PP
Sbjct: 835 LERSVKLAQ-EGRAPVECPSLGPVPH--------RPPFEPGSAVATVPP 874
Score = 37.4 bits (85), Expect = 0.37
Identities = 45/164 (27%), Positives = 65/164 (39%), Gaps = 24/164 (14%)
Query: 3236 HVTEQQSMVQKQLEQIRKQQKEH------------AELIEDYRIKQQQQCAMAPPTMMPS 3283
H +QQ Q+Q +Q ++QQ++H +E AM+P + S
Sbjct: 481 HHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSP--SLGS 538
Query: 3284 VQPQPPLIPGATPPTMSQPTF----PMVPQQLQHQQHTTVISGHTSPVRMPSLPGWQPNS 3339
++P PP P PP SQ ++ P P ++ S + P PS P P
Sbjct: 539 LRPYPP-GPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPS-PSQGPQG 596
Query: 3340 APAHLPLNPPRIQPPIAQLP--IKTCTPAPGTVSNANPQSGPPP 3381
AP P P + A L I T +P A+P GPPP
Sbjct: 597 APYPFP-PVPTVTTSSATLSTVIATVASSPAGYKTASP-PGPPP 638
Score = 37.0 bits (84), Expect = 0.48
Identities = 40/129 (31%), Positives = 53/129 (41%), Gaps = 29/129 (22%)
Query: 3276 APPTMMPSVQPQPPLIPGATPPTMSQPTFPMVPQQ-------------LQHQQHTTVISG 3322
APP P P P L PG T +S P PM P+ QH TT IS
Sbjct: 208 APPGAPP---PHPQLYPGGTGGVLSGP--PMGPKGGGAASSVGGPNGGKQHPPPTTPISV 262
Query: 3323 HTS------PVRMPSLP---GWQPNSAP-AHLPLNPPRIQPPIAQLPIKTCTPAPGTVSN 3372
+S P + P+ P G P++ P A+ P P + PP A P+ + +P +
Sbjct: 263 SSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPALRPLNNASASPPGL-G 321
Query: 3373 ANPQSGPPP 3381
A P G P
Sbjct: 322 AQPLPGHLP 330
Score = 34.3 bits (77), Expect = 3.1
Identities = 63/285 (22%), Positives = 92/285 (32%), Gaps = 69/285 (24%)
Query: 2415 PHPG--PLQHWQPEN--VNQAFTRPP---PP----YPGNIRSPVA-PPLGPRYAVFPKDQ 2462
PHP P + P ++ F PP PP YPG ++ PP+GP+
Sbjct: 185 PHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSV 244
Query: 2463 RGP-----YPPDVASMGMRPHGFRFGFPGGSHGTMPSQERFLVPPQQIQGSGVSPQLRRS 2517
GP +PP + + G+ G P++ PP G G P
Sbjct: 245 GGPNGGKQHPPPTTPISVSS--------SGASGAPPTK-----PPTTPVGGGNLPSAPPP 291
Query: 2518 -----VSVDMPRPLNNSQMNNPVGLPQHFSPQSLP--VQQHNILGQAYIEL--------- 2561
V+ ++P P +NN P Q LP + + +GQ L
Sbjct: 292 ANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPT 351
Query: 2562 -----------RHRAPDGRQRLPFSAPPGSVVEASSNLRHGNFIPRP------------D 2598
AP R P+S+ S ASS+ + P
Sbjct: 352 LAPSPHSLPPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHS 411
Query: 2599 FPGPRHTDPMRRPPQGLPNQLPVHPDLEQVPPSQQEQGHSVHSSS 2643
FP P +PP+ LP Q PP G + +S+
Sbjct: 412 FPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSN 456
Score = 33.9 bits (76), Expect = 4.1
Identities = 53/212 (25%), Positives = 73/212 (34%), Gaps = 25/212 (11%)
Query: 3972 PASLPTPPHNNQEELRIQDHCGDRDTPDSFVPSSSPESVVGVEVSRYPDLSLVKEEPPEP 4031
PA LP PPH+ G P S +SS + G +P S + P P
Sbjct: 546 PAHLP-PPHSQVS----YSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYP 600
Query: 4032 VPSPIIPILPSTAGKSSESRRNDIKTEPGTLYFASPFGPSPNGPRSGLISVAITLHPTAA 4091
P P+ + S+A S+ + + P ASP GP P G R+ T P
Sbjct: 601 FP-PVPTVTTSSATLSTVIAT--VASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGY 657
Query: 4092 ENISSVVAAFSDLLHVRIPNSYEVSSAPDVPSMGLVSSHRINPG---LEYRQHLLLRGPP 4148
+ S P Y +S P P S + PG L PP
Sbjct: 658 KPGS------PPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLPPAGPSGLPSLPPP 711
Query: 4149 PGSANPPRLVSSYRLKQ--------PNVPFPP 4172
P + +S+ ++KQ P P PP
Sbjct: 712 PAAPASGPPLSATQIKQEPAEEYETPESPVPP 743
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 85.1 bits (209), Expect = 2e-15
Identities = 231/1031 (22%), Positives = 325/1031 (31%), Gaps = 186/1031 (18%)
Query: 1801 TPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAPPP----- 1855
TP S P TP P PA + P P + S P A PP
Sbjct: 946 TPPSPKGGPATPSPKWAPTPPAAT------PPSPKGGPATPSPKGAPTPPAATPPSPKGG 999
Query: 1856 --PPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRP------ 1907
P+P P +++ P+ F G+S +P P TP P
Sbjct: 1000 PATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTT 1059
Query: 1908 -------PPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNN 1960
P G + A TP S P + A P
Sbjct: 1060 PAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLAT 1119
Query: 1961 DPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQ 2020
P+ P T P T PK GL+ P T P P+
Sbjct: 1120 PPHKGAPTT--PAATPPSPKG-GLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPA 1176
Query: 2021 RIPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPR 2080
P S L TP+P G TP PPS P G ++ S + + P A P
Sbjct: 1177 ATPPSPKGGLATPSP----KGAPTTPAATPPS---PKGGLATPSPKGA--PTTPAATPPS 1227
Query: 2081 PIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPP--GTP 2138
P + + P TP P + P + P+ + + PP G P
Sbjct: 1228 PKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAP 1287
Query: 2139 RP-VVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQ--PQTPRP-STQTDLFVTPV 2194
P VV S G A S P G P P P S + P TP P T VTP
Sbjct: 1288 NPAVVTPPSPKGGPAT------SPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPP 1341
Query: 2195 TNQRHSDPYAHPPGTPRPGISVPYSQ-PPATPRPRISEGFTRSSMTRPVLMPNQ---DPF 2250
+ P GTP + P S+ P TP ++ T P P+
Sbjct: 1342 S----------PKGTPTLPATTPSSKGGPTTPS-------SKEGPTPPAATPSHKGGPAM 1384
Query: 2251 LQAAQNRGPALPGPLVRP------PDTCSQTPRPP-------GPGLSD-TFSRVSP---- 2292
+ RGPA+P P P P + + P P P D T V+P
Sbjct: 1385 TPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLK 1444
Query: 2293 -SAARDPYDQSPMTPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQF-S 2350
+ A P TP S+ D + T + P P A+S+SP +
Sbjct: 1445 KAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQ----VATSSSPKKAPATPAPM 1500
Query: 2351 GVSQLPGPVPTS--GVTDTQNTVNMAQADTEKLRQRQ---------------------KL 2387
G LP +P+S V T ++ A T L ++ K
Sbjct: 1501 GAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKK 1560
Query: 2388 REIILQQQQQKKIAGRQEKGSQDS------------------PAVPHPGPLQHWQPENVN 2429
I ++ +E S + PAV P P + P V
Sbjct: 1561 TPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVT 1620
Query: 2430 QAFTRPPPPYPGNIRSPVAPPLGPRYAVFPKDQRGPYPPDVASMGMRPHGFRFGFPGGSH 2489
P P +P +PP+ P KD MG G P
Sbjct: 1621 PPSPEKGPATPAPKGTPTSPPVTPSSL---KDSPTSPASVTCKMGATVPQASKGLP-AKK 1676
Query: 2490 GTMPSQERFLVP-----PQQIQGSGVSPQLRRSVSVDMPRPLNNSQMNNPVGLPQHFSPQ 2544
G +E + P P + PQ ++S + P + S N G +P
Sbjct: 1677 GPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPA 1736
Query: 2545 S-LPVQQHNILGQAYIELRHRAPDGRQRLPFSAPPGSVVEASSNLRHGNF---IPRPDFP 2600
LPVQ+ + + H +P G APP S +AS+ L F +P+P+
Sbjct: 1737 PLLPVQKDSSKTAKGKDASH-SPKGP-----LAPPES--KASTPLTAAAFEKVLPKPE-- 1786
Query: 2601 GPRHTDPMRRPPQGL---PNQLPVHPDLEQVPPSQQEQGHSVHSSSMVMRTLNHPLGGEF 2657
PP L P+ +P P +Q PS S +V+ + + PL
Sbjct: 1787 -SASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPS---------SPGLVLESPSKPLAPAD 1836
Query: 2658 SE--------APLSTSVPSETTSDNLQITTQPSDGLEEKLDSDDPSVKELDVKDLEGVEV 2709
+ P+S VP ++ N+ T S G + PS K+ K+ +G
Sbjct: 1837 EDELLPLIPPEPISGGVPFQSVLVNM--PTPKSAG----IPVPTPSAKQPVTKNNKGSGT 1890
Query: 2710 KDLDDEDLENL 2720
+ DE + L
Sbjct: 1891 ESDSDESVPEL 1901
Score = 84.7 bits (208), Expect = 2e-15
Identities = 206/964 (21%), Positives = 303/964 (31%), Gaps = 140/964 (14%)
Query: 1793 LLVQSGSDTPSSGIQSPLTPQP-GNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVK-- 1849
L Q D+P++ SP P P G S + T P TPT + + F K
Sbjct: 841 LSFQGSKDSPAT-THSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEG 899
Query: 1850 PQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVG------ 1903
P P P AP+ S +A+ + P SP + P P + G
Sbjct: 900 PATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSP 959
Query: 1904 --TPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNND 1961
P PP + A P P + P A PSP + T
Sbjct: 960 KWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPAT-PSPKGAPTPPAVTPPS 1018
Query: 1962 PYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKG-------PIAAGTSDHFTKPSPRA 2014
P P TP FPK G S P + + KG P A T+ T PSP+
Sbjct: 1019 PKGSPAATP-------FPK--GASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKG 1069
Query: 2015 DVFQRQRIPDSYARPLLTPAPLDSG---PGPFKTPMQPPPSSQDPYGSVSQASRRLSVDP 2071
+ + P TP G P P PM P + P G ++ + + P
Sbjct: 1070 GP-ATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGA--P 1126
Query: 2072 YERPALTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPY 2131
A P P + + P TP P + P PT+ P
Sbjct: 1127 TTPAATPPSPKGGLATPPPKGAPTTPAATP--------PSPKGGLATPPPKGAPTT--PA 1176
Query: 2132 SQPPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPSTQTDLFV 2191
+ PP +P+ + + S P S G P+ + TP PS + L
Sbjct: 1177 ATPP-SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP-PSPKGGL-A 1233
Query: 2192 TPVTNQRHSDPYAHPPGTPRPGISVPYSQ----PPATPRPRISEGFTRSSMTRPVLMPNQ 2247
TP + P A PP +P+ G + P + PPA P + G PN
Sbjct: 1234 TPSPKGAPTTPAATPP-SPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKG---APNP 1289
Query: 2248 DPFLQAAQNRGPALPGPLVRPPDTCSQTPRPPG-PGLSDTFSRVSPSAARDPYDQ-SPMT 2305
+ GPA P P + P P G PG +P A P + +P
Sbjct: 1290 AVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTL 1349
Query: 2306 PRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPV------ 2359
P + S G T P S+ + +P H G + S GP
Sbjct: 1350 PATTPSSKGGPTT---------PSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKG 1400
Query: 2360 -PTSGV-------------TDTQNTVNMAQAD-TEKLRQRQKLREIILQQQQQKKIAGRQ 2404
PTS + ++ D T L++ + A
Sbjct: 1401 DPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPS 1460
Query: 2405 EKGSQDSPAVPHPGPLQHWQPENV-NQAFTRPPPPYPGNIRSPVAPPLGP----RYAVFP 2459
KG PAV P P + P+ V + + P P + +P P + P P
Sbjct: 1461 SKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATP 1520
Query: 2460 KDQRGPYPPDVASMGMRPHGFRFGFPGGSHGTMPSQERFLVPPQQIQGSGVSPQLRRSVS 2519
+R P P + + + T+ +E + P + P +++ +
Sbjct: 1521 SSRRDPIAPTATLLSKK-----------TPATLAPKEALIPPAMTV------PSPKKTPA 1563
Query: 2520 VDMPRPLNNSQMNNPVGLPQHFSPQSLPVQQHNILGQAYIELRHRAPDGRQRLPFSAPPG 2579
+ P+ + + P +P + AP ++ L PP
Sbjct: 1564 IPTPKEAPATPSSKEASSPPAVTPSTY----------------KGAPSPKELL---IPP- 1603
Query: 2580 SVVEASSNLRHGNFIPRPDFPGPRHTDPMRRPPQGLPNQLPVHP-DLEQVPPSQQ----E 2634
S + + P P P P P+G P PV P L+ P S +
Sbjct: 1604 --AVTSPSPKEAPTPPAVTPPSP-EKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCK 1660
Query: 2635 QGHSVHSSSMVMRTLNHPLG-GEFSEAPLSTSVPSETTSDNLQITTQPSDGLEEKLDSDD 2693
G +V +S + P E AP S P T T+ S + D
Sbjct: 1661 MGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPI-CPD 1719
Query: 2694 PSVK 2697
PS K
Sbjct: 1720 PSAK 1723
Score = 83.6 bits (205), Expect = 5e-15
Identities = 181/811 (22%), Positives = 261/811 (32%), Gaps = 185/811 (22%)
Query: 1793 LLVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQA 1852
L S P++ +P +P+ G SP + P +TP S P+
Sbjct: 1209 LATPSPKGAPTTPAATPPSPKGGLATPSPKGA------PTTPAATPPSPKGGPATPPPKG 1262
Query: 1853 PPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPS--PMDPYAKMVGTPRPPPV 1910
P PPA + ++ L+ P+P V +P S P + P TP P P
Sbjct: 1263 APTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATP-PSPK 1321
Query: 1911 GHSFSRRNSAAPVENC-TPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDT 1969
G + AP TP S P T +++ P SS P A P
Sbjct: 1322 GSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTP--SSKEGPTPPAATPSHK 1379
Query: 1970 PRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARP 2029
P MT PK R P + PSP+ D IP S +
Sbjct: 1380 GGPAMTPPSPK-----RGPAI-------------------PSPKGDPTSPAVIPLSPKKA 1415
Query: 2030 LLTPAPLDSGPGPFKTPMQPP----------PSSQDPYGSVSQASRRLSVDPYERPALTP 2079
TP + P K + PP P++ P G + S + DP PA+TP
Sbjct: 1416 PATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSK--GDP-TLPAVTP 1472
Query: 2080 RPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPR 2139
P P P + + P +A + P + PT P
Sbjct: 1473 ---------------PSPKEPPAPKQVATSSSPKKAPATPAPMGAPT----------LPA 1507
Query: 2140 PVVDSYSQSSGTARSNTDPYS--------QPPGT--PRPTTVDPYSQQP---QTPRPSTQ 2186
+ S + T S DP + + P T P+ + P P +TP T
Sbjct: 1508 VIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTP 1567
Query: 2187 TDLFVTPVTNQRHSDPYAHP---PGTPRPGISVPYSQPPATPRPRISEGFTRSSMTRPVL 2243
+ TP + + S P P G P P PPA P E T ++T P
Sbjct: 1568 KEAPATPSSKEASSPPAVTPSTYKGAPSP---KELLIPPAVTSPSPKEAPTPPAVTPP-- 1622
Query: 2244 MPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSP 2303
+ +GPA P P P PP V+PS+ +D SP
Sbjct: 1623 ----------SPEKGPATPAPKGTPTS-------PP----------VTPSSLKD----SP 1651
Query: 2304 MTPRSQSDSFGTS--------------QTAHDVADQPRPGSEGSFCASSNSPMHSQGQQF 2349
+P S + G + +V P P S A + ++
Sbjct: 1652 TSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSA 1711
Query: 2350 SGVSQLPGPVPTSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKKIAGRQEKGSQ 2409
+ P P +G +TV A + +Q+ K G+ S
Sbjct: 1712 TSPPICPDPSAKNGSKGPLSTVAPAPL-------------LPVQKDSSKTAKGKDASHSP 1758
Query: 2410 DSPAVPHPGPLQHWQPENVNQAFTRP-PPPYPGNIRSPVAPPL------GPRYAVFPKDQ 2462
P P P AF + P P ++ + +PP+ P + PK Q
Sbjct: 1759 KGPLAP---PESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQ 1815
Query: 2463 RGPYPPD-VASMGMRPHGFRFGFPGGSHGTMPSQERFLVPPQQIQGSGVSPQLRRSVSVD 2521
P P V +P P +P L+PP+ I G GV Q SV V+
Sbjct: 1816 FLPSSPGLVLESPSKPLA-----PADEDELLP-----LIPPEPISG-GVPFQ---SVLVN 1861
Query: 2522 MPRPLNNSQMNNPVGLPQHFSPQSLPVQQHN 2552
MP P G+P PV ++N
Sbjct: 1862 MPTP-------KSAGIPVPTPSAKQPVTKNN 1885
Score = 59.7 bits (143), Expect = 7e-08
Identities = 202/935 (21%), Positives = 292/935 (31%), Gaps = 131/935 (14%)
Query: 1835 PSTPTSTSSDDVFVKPQAPPPPPAPS-------RIPIQDSLSQAQTSQPPSPQVFSPGSS 1887
PST +T+ + V P P P + + P Q L S +P FSP +
Sbjct: 493 PSTQVATTLR-IPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAP--FSPAQA 549
Query: 1888 NSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNSAAPV----ENCTPLSSVSRPLQMNETTA 1943
+ P+ P SF +S+ + E S+ PL + + +
Sbjct: 550 GLTTKKDPTVLPLVQAAPKNSP---SFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPAS 606
Query: 1944 NRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTDQ--------FPKSLGLSRSPV-VSEQT 1994
+ SP+ S+S D YA PD+ P++ FP S P V+ T
Sbjct: 607 SMTSPLGVNSSASVIKTDSYA-GPDSAGPLLKSSLITPTVAAFPLE---SADPAGVAPTT 662
Query: 1995 AKG-----------------------PIAAGTSDHFTKPSPRADVFQRQRIPDSYARPL- 2030
AKG P+ GT ++ P + PL
Sbjct: 663 AKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLA 722
Query: 2031 ---LTPAPLDSGPGPFKTPMQPPPSSQDPYG-SVSQASRRLSVDPYERP---------AL 2077
L P S P P P PP ++ G S + A ++ P E P A
Sbjct: 723 TLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATAS 782
Query: 2078 TPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGT 2137
+ + + + S S P T P + A P G +S P S S P
Sbjct: 783 SKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPI---GNLSSPVSPVEASFLPEN 839
Query: 2138 PRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQ 2197
S S T S T P P G P P+ V P S + T P V +
Sbjct: 840 SLSFQGS-KDSPATTHSPTPP--SPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFP 896
Query: 2198 RHSDPYAHPPGTPRPGISVPYSQPP---ATPRPRISEGFTRSSMTRPVLMPNQDPFLQAA 2254
+ A P P +S+ S P ATP P+ G S P P +
Sbjct: 897 KEGP--ATPAPKQAPALSMTSSSPKKARATPAPK---GIPAS--PSPKGAPTPPAATPPS 949
Query: 2255 QNRGPALPGPLVRPPDTCSQTPRPP-GPGLSDTFSRVSPSAARDPYDQ-SPMTPRSQSDS 2312
GPA P P P + P P GP +P AA P + P TP +
Sbjct: 950 PKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAP 1009
Query: 2313 FGTSQTAHDVADQP--RPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQNT 2370
+ T P P +G+ + +P +G + LP PT+ +
Sbjct: 1010 TPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGS--PAATPLPKGAPTTPAATLPSP 1067
Query: 2371 VNMAQADTEKLRQRQKLREIILQQQQQKKIAGRQEKGSQDSPAVPHPGPLQHWQPENVNQ 2430
+ K + A KG+ PA P P
Sbjct: 1068 KGGPATPSLK---GAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSP----------- 1113
Query: 2431 AFTRPPPPYPGNIRSPVAPPLGPRYAVFPKDQRGPYPPDVASMGMRPHGFRF-----GFP 2485
PP+ G +P A P P+ + +G P A+ P G G P
Sbjct: 1114 KGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGA-PTTPAATPPSPKGGLATPPPKGAP 1172
Query: 2486 GGSHGTMPSQERFLVPPQQIQGSGVSPQLRRSVSVDMPRPLNNSQMNNPVGLPQHFSPQS 2545
T PS + L P +G+ +P + P P +P G P +P +
Sbjct: 1173 TTPAATPPSPKGGLATPSP-KGAPTTP------AATPPSPKGGLATPSPKGAPT--TPAA 1223
Query: 2546 LPVQQHNILGQAYIELRHRAPDGRQRLPFSAPPGSVVEASSNLRHGNFIPRPDFPGPRHT 2605
P L +P G P + PP ++ G P P
Sbjct: 1224 TPPSPKGGLATP-------SPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKG 1276
Query: 2606 DPMRRPPQGLPNQLPVHPDLEQ-VPPSQQEQGHSVHSSSMVMRTLNHPLGGEFSEAPLST 2664
P +G PN V P + P + +G ++ T P G + P
Sbjct: 1277 GLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAA----TPPSPKGSPGTPPPKGA 1332
Query: 2665 SVPSETTSDNLQIT-TQPSDGLEEKLDSDDPSVKE 2698
P T + + T T P+ K PS KE
Sbjct: 1333 PTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKE 1367
Score = 48.1 bits (113), Expect = 2e-04
Identities = 128/568 (22%), Positives = 188/568 (33%), Gaps = 88/568 (15%)
Query: 3495 SPSTQTFMQTNERRQVGPPSFVPDSPSIPVGSPNFSSVKQGHGNLSGTSFQQSPVRPSFT 3554
+P T+ T + + PP+ P S +P S+ K G S P P+ T
Sbjct: 1418 TPVTREGAATPSKGDLTPPAVTPVSLK---KAPATSAPKGGPATPSSKG---DPTLPAVT 1471
Query: 3555 PALPAAPP----VANSSLPCGQDSTITHGHSYPGSTQSLIQLYSDIIPEEKGKKKRTRKK 3610
P P PP VA SS P +T P +L +IP + T
Sbjct: 1472 PPSPKEPPAPKQVATSSSPKKAPATPA-----PMGAPTL----PAVIPSSPKEVPATPSS 1522
Query: 3611 KRDDDAE-----STKAPST-PHSDITAPPTPGISETTSTPAVSTPSELPQQADQESVEPV 3664
+RD A S K P+T + PP + TPA+ TP E P +
Sbjct: 1523 RRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSP 1582
Query: 3665 GPSTPNMAAGQLCTELENKLPNSDFSQATPNQQTYANSEVDKLSMETPAKTEEIKLEKAE 3724
TP+ G P+ P + + E TP E+ A
Sbjct: 1583 PAVTPSTYKG---------APSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAP 1633
Query: 3725 --TESCPGQEEPKLEEQNGSKVEGNAVACPVSSAQSPPHSAGAPAAKGDSGNELLKHLL- 3781
T + P L++ S +V C + A P S G PA KG + LK +L
Sbjct: 1634 KGTPTSPPVTPSSLKD---SPTSPASVTCKM-GATVPQASKGLPAKKGPTA---LKEVLV 1686
Query: 3782 -KNKKSSSLLN-------QKPEGSICSEDDCTKDNKLVEKQNPAEGLQTLGAQMQGGFGC 3833
+S+ ++ Q + S S C + + P L T+
Sbjct: 1687 APAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGP---LSTVAP-------- 1735
Query: 3834 GNQLPKTDGGSETKKQRSKRTQRTGEKAAPRSKKRKKDEEEKQAMYSSTDTFTHLKQQNN 3893
LP S+T K + G A P SK ++ + + +
Sbjct: 1736 APLLPVQKDSSKTAKGKDASHSPKGPLAPPESK------ASTPLTAAAFEKVLPKPESAS 1789
Query: 3894 LSNPPTPPASLPPTPPPMACQKMANGFATTEELAGKAGVLVSHEVTKTLGP--KPFQLPF 3951
+S P+PP SLP P P+ F L G LV +K L P + LP
Sbjct: 1790 VSAAPSPPVSLPLAPSPVPTLPPKQQF-----LPSSPG-LVLESPSKPLAPADEDELLPL 1843
Query: 3952 RPQDDLLARALAQG-------PKTVDVPASLPTPPHNNQEELRIQDHCGDRDTPDSFVPS 4004
P + + Q PK+ +P +PT P Q + G D VP
Sbjct: 1844 IPPEPISGGVPFQSVLVNMPTPKSAGIP--VPT-PSAKQPVTKNNKGSGTESDSDESVPE 1900
Query: 4005 SSPESVVGVEVSRYPDLSLVKEEPPEPV 4032
+ ++ L+ E EPV
Sbjct: 1901 LEEQDSTQA-TTQQAQLAAAAEIDEEPV 1927
Score = 45.4 bits (106), Expect = 0.001
Identities = 114/517 (22%), Positives = 179/517 (34%), Gaps = 103/517 (19%)
Query: 3276 APPTMMPSVQPQPP------LIPGATPPTMSQPTFPMVPQQLQHQQHTTVISGHTSPVRM 3329
AP T P P P +P TPP+ P P P+Q+ +P+
Sbjct: 1446 APATSAPKGGPATPSSKGDPTLPAVTPPS---PKEPPAPKQVATSSSPKKAPATPAPMGA 1502
Query: 3330 PSLPGWQPNSAPAHLPLNPPRIQPPIAQLPIKTCTPAPGTVSNANPQSGPPPRVEFDDNN 3389
P+LP P S+P +P P + PIA P T++ P V
Sbjct: 1503 PTLPAVIP-SSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKT 1561
Query: 3390 PFSESFQERERKERLREQQERQRIQLMQEVDRQRALQQRMEMEQHGMVGSEISSSRTSVS 3449
P + +E +E +SS +V+
Sbjct: 1562 PAIPTPKEAPATPSSKE-----------------------------------ASSPPAVT 1586
Query: 3450 QIPFYSSDLPCDFMQPLGPLQQSPQHQQQMGQVLQQQNIQQGSINSPSTQTFMQTNERRQ 3509
+ + P + + P SP+ + + + ++G P+T T
Sbjct: 1587 PSTYKGAPSPKELLIPPAVTSPSPK-EAPTPPAVTPPSPEKG----PATPAPKGTPTSPP 1641
Query: 3510 VGPPSFVPDSPSIP--VGSPNFSSVKQGHGNLSG----TSFQQSPVRPS--FTPALPA-- 3559
V PS + DSP+ P V ++V Q L T+ ++ V P+ TP + A
Sbjct: 1642 V-TPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPT 1700
Query: 3560 --APPVANSSL---PCGQDSTITHGHSYPGSTQSLIQLYSDIIPEEKGKKKRTRKKKRDD 3614
P SS P D + +G P ST + + ++P +K K + K D
Sbjct: 1701 RKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVA----PAPLLPVQKDSSKTAKGK---D 1753
Query: 3615 DAESTKAP-STPHSDITAP----------PTPGISETTSTPAVS-----TPSELPQQADQ 3658
+ S K P + P S + P P P + ++ P+ PS +P +
Sbjct: 1754 ASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPK 1813
Query: 3659 ESVEP-------VGPSTPNMAAGQLCTELENKLPNSDFSQATPNQQTYANSEVDK---LS 3708
+ P PS P A + EL +P S P Q N K +
Sbjct: 1814 QQFLPSSPGLVLESPSKPLAPADE--DELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIP 1871
Query: 3709 METP-AKTEEIKLEKAE-TESCPGQEEPKLEEQNGSK 3743
+ TP AK K K TES + P+LEEQ+ ++
Sbjct: 1872 VPTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQ 1908
Score = 44.3 bits (103), Expect = 0.003
Identities = 135/618 (21%), Positives = 187/618 (30%), Gaps = 94/618 (15%)
Query: 3512 PPSFVPDSPSI-----PVGSPNFSSVKQGHGNLSGTSFQQSPVRPSFTPA---LPAAPPV 3563
PP P +PS+ P P + KQ LS TS SP + TPA +PA+P
Sbjct: 881 PPKETP-TPSVVNLPFPKEGPATPAPKQAPA-LSMTS--SSPKKARATPAPKGIPASPSP 936
Query: 3564 ANSSLPCGQDSTITHGHSYPGSTQSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTKAPS 3623
+ P G S + + P KG K T +
Sbjct: 937 KGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPK-----GAPTPPAA 991
Query: 3624 TPHSDITAPPTPGISETTSTPAVSTPSELPQQADQESVEPVGPSTPNMAAGQLCTELENK 3683
TP S P TP + PAV+ PS P+ + + P G STP A
Sbjct: 992 TPPSPKGGPATPSPKGAPTPPAVTPPS--PKGSPAATPFPKGASTPPAAT---------- 1039
Query: 3684 LPNSDFSQATPNQQTYANSEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKL---EEQN 3740
P S + +P A + + K + TPA T T S G P
Sbjct: 1040 -PPS--PKGSP-----AATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPK 1091
Query: 3741 GSKVEGNAVACPVSSAQSPPHSAGAPAAKGDSGNELLKHLLKNKKSSSLLNQKPEGSICS 3800
G + P+ A +PP G A G L P+G+ +
Sbjct: 1092 GGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTT 1151
Query: 3801 EDDCTKDNKLVEKQNPAEGLQTLGAQMQGGFGCGNQLPKTDGGSETKKQRSKRTQRTGEK 3860
K P +G T A P GG T + T T
Sbjct: 1152 PAATPPSPKGGLATPPPKGAPTTPAATP---------PSPKGGLATPSPKGAPT--TPAA 1200
Query: 3861 AAPRSKKRKKDEEEKQAMYSSTDTFTHLKQQNNLSNP-----PTPPASLPPTP------- 3908
P K K A +T T + L+ P PT PA+ PP+P
Sbjct: 1201 TPPSPKGGLATPSPKGA--PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATP 1258
Query: 3909 -------PPMACQKMANGFATTEELAGKAGVLVSHEVTKTLGPKPFQLPFRPQDDLLARA 3961
PP A G T G V + GP P
Sbjct: 1259 PPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPP 1318
Query: 3962 LAQGPKTVDVPASLPTPPHNNQEELR--------IQDHCGDRDTPDS----FVPSSSPES 4009
+G P PTPP + G TP S P+++P
Sbjct: 1319 SPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSH 1378
Query: 4010 VVGVEVS-----RYPDLSLVKEEPPEPVPSPI----IPILPSTAGKSSESRRNDIKTEPG 4060
G ++ R P + K +P P P+ P P T ++ + D+ T P
Sbjct: 1379 KGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDL-TPPA 1437
Query: 4061 TLYFASPFGPSPNGPRSG 4078
+ P+ + P+ G
Sbjct: 1438 VTPVSLKKAPATSAPKGG 1455
Score = 40.0 bits (92), Expect = 0.057
Identities = 156/755 (20%), Positives = 238/755 (31%), Gaps = 114/755 (15%)
Query: 3512 PPSFVPDSPS-------IPVGSPNF--SSVKQGHGNLSGTSFQQSPVRPSFTPALPAA-- 3560
PP+ P SP +P G+P +++ G + S + +P P+ TP P
Sbjct: 1035 PPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGP 1094
Query: 3561 ----------PPVANSSLPCGQDSTITH--GHSYPGSTQSLIQLYSDIIPEEKGKKKRTR 3608
PP A P G +T H + P +T P KG
Sbjct: 1095 ATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATP----------PSPKGGLATPP 1144
Query: 3609 KKKRDDDAESTK--------------APSTPHSDITAPP----TPGISETTSTPAVSTPS 3650
K +T AP+TP + +P TP +TPA + PS
Sbjct: 1145 PKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPS 1204
Query: 3651 ELPQQADQESV-EPVGPS-TPNMAAGQLCTELENKLPNSDFSQATPNQQTYANSEVDKLS 3708
A P P+ TP G L T P + ATP +
Sbjct: 1205 PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP--AATPPSPKGGPATPPPKG 1262
Query: 3709 METPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVEGNAVACPVSSAQSPPHSAGAPAA 3768
TP L K + P + P +G P A +PP +A P+
Sbjct: 1263 APTPPAATPPSL-KGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPP-AATPPSP 1320
Query: 3769 KGDSGNELLKHLLKNKKSSSLLNQKPEGSICSEDDCTKDNKLVEKQNPAEGLQTLGAQMQ 3828
KG G K ++ P+G+ + EG A
Sbjct: 1321 KGSPGTPPPKGA---PTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPS 1377
Query: 3829 GGFGCGNQLPKTDGGSETKKQRSKRTQRTGEKAAPRSKKRKKDEEEKQAMYSSTD----- 3883
G P G + T +P+ E A S D
Sbjct: 1378 HKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPA 1437
Query: 3884 -TFTHLKQQNNLSNP------------PTPPASLPPTP-PPMACQKMANGFATTEELAGK 3929
T LK+ S P PT PA PP+P P A +++A + + A
Sbjct: 1438 VTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATP 1497
Query: 3930 A--------GVLVSHEVTKTLGPKPFQLPFRPQDDLLARAL--------AQGPKTVDVPA 3973
A V+ S P + P P LL++ A P + VP+
Sbjct: 1498 APMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPS 1557
Query: 3974 SLPTPPHNNQEELRIQDHCGDRDTPDSFVPSSSPESVVGVEVSRYPDLSLVKEEPPE-PV 4032
TP +E + +P + PS+ + E+ P ++ P E P
Sbjct: 1558 PKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPP--AVTSPSPKEAPT 1615
Query: 4033 PSPIIPILPSTAGKSSESRRNDIKTEPGTLYFASPFGPSPNGPRSGLISVAITLHPTAAE 4092
P + P P G ++ + + + P T S SP P S + T+ P A++
Sbjct: 1616 PPAVTPPSPE-KGPATPAPKGTPTSPPVT---PSSLKDSPTSPASVTCKMGATV-PQASK 1670
Query: 4093 NISSV--VAAFSDLLHVRIPNSYEVSSAPDVPSMGLVSSHRINPGLEYRQHLLLRGPPPG 4150
+ + A ++L P S + +AP S +P + P P
Sbjct: 1671 GLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPI---------CPDPS 1721
Query: 4151 SANPPRLVSSYRLKQPNVPFPPTSNGLSGYKDSSH 4185
+ N + S P +P S+ + KD+SH
Sbjct: 1722 AKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASH 1756
Score = 33.1 bits (74), Expect = 7.0
Identities = 86/356 (24%), Positives = 117/356 (32%), Gaps = 67/356 (18%)
Query: 2040 PGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERP---ALTPRPIDNFSHNQSND--PY 2094
PGP P P Q P + +QAS P+ P A TP + F + S P
Sbjct: 41 PGPTLPPPCSPAPQQCPLSAANQAS------PFPSPSTIASTPLEVP-FPQSSSGTALPL 93
Query: 2095 SQPPLTP-------HPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQ 2147
P P P ++ + + P P+S P + P V Q
Sbjct: 94 GTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSV-----Q 148
Query: 2148 SSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPP 2207
S N + PP + + +T+L N+ S+ +P
Sbjct: 149 KSSAFPPNL--LTSPPSVAVAESGSVITLSAPIAPSEPKTNL------NKVPSEVVPNPK 200
Query: 2208 GTPRPGI---SVPYSQPPATPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRGPALPGP 2264
GTP P +VPY TP I G T P A+ P
Sbjct: 201 GTPSPPCIVSTVPYH--CVTPMASIQSGVASLPQTTPTTT--------------LAIASP 244
Query: 2265 LVRPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQS-PMTPRSQSDSFGTSQTAHDVA 2323
V+ S P PG VSP AA QS P+ SQ +TA
Sbjct: 245 QVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQ-------KTAGPNT 297
Query: 2324 DQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTD-TQNTVNMAQADT 2378
P S GS A P+H Q G QL G S ++D T T+++ + T
Sbjct: 298 PPDFPISLGSHLA----PLH---QSSFGSVQLLGQTGPSALSDPTVKTISVDHSST 346
Score = 32.7 bits (73), Expect = 9.1
Identities = 44/175 (25%), Positives = 64/175 (36%), Gaps = 31/175 (17%)
Query: 2809 KHSPQKKSTVTNEVKTEVLS-PNSKVESKCETEKNDENKDNVDTPCSQASAHSDLNDGEK 2867
K P KK + + LS P S VE+ E + + + D+P A+ HS K
Sbjct: 806 KRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSP---ATTHSPTPPSPK 862
Query: 2868 --------TSLHPCDPDLFEKRTNRETAGPSANVI-----QASTQLPAQDVINSCGITGS 2914
T L P L K T P+ +V+ + PA + +T S
Sbjct: 863 GAPTPSAVTPLSPKGVTLPPKET------PTPSVVNLPFPKEGPATPAPKQAPALSMTSS 916
Query: 2915 TPVLSSLLANEKSDNSDIRPSGSPPPPTL--------PASPSNHVSSLPPFIAPP 2961
+P + K + P G+P PP PA+PS + PP PP
Sbjct: 917 SPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPP 971
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 84.0 bits (206), Expect = 3e-15
Identities = 132/527 (25%), Positives = 187/527 (35%), Gaps = 85/527 (16%)
Query: 1861 RIPIQDSLSQAQTSQPPSPQVFSPGSS-NSRPPSPMDPYAKM----------VGTPRPPP 1909
RI ++++++ + ++ P S G+ ++ P+P P M VG PRP P
Sbjct: 126 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP 185
Query: 1910 VGHSFS------RRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPY 1963
+ S+A + T S +R RP+ R L SS+T + P
Sbjct: 186 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS-RSLSSSATPLSSPA 244
Query: 1964 AKPPD---TPRPVMTDQFPKSLGLS--RSPVVSEQTAKGPIAAG--TSDHFTKPSPRADV 2016
P TPR PK GL R P V+ A G +S PSP A
Sbjct: 245 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAP- 303
Query: 2017 FQRQRIPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVS-QASRRLSVDPYERP 2075
P A P L P P PP + GS + QA+ P P
Sbjct: 304 ------PSPSAPPSLQTLP--------SPPATPPSQATTSLGSPTLQATHSFLPSPPLSP 349
Query: 2076 ALTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPP 2135
TP P + P PP P A PS P ++ Q P+S PP
Sbjct: 350 LATPPP--QAPPALALPPLQAPPSPPASPPLSPLATPSP--QAPNALAVHLLQAPFSPPP 405
Query: 2136 GTPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPSTQTDLFVTPVT 2195
P + S A P + PP P+ P Q P +P S TP
Sbjct: 406 SPP-----VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP-- 458
Query: 2196 NQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQ 2255
P A PP P + ++PP P ++ ++ + P P Q PF +A
Sbjct: 459 -----PPQAPPPLAAPP---LQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 510
Query: 2256 -----------NRGPALPGPLVRPPDTCSQTP------RPPGPGLSDTFS--RVSPSAA- 2295
P L PL++ P + +P RPP PG + S R++ + A
Sbjct: 511 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 570
Query: 2296 --RDPYDQSPMTPRSQSDSFGTSQTAHDVADQPR---PGSEGSFCAS 2337
P +SP + S D G S +A ++ R G EG AS
Sbjct: 571 GPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAAS 617
Score = 74.3 bits (181), Expect = 3e-12
Identities = 121/489 (24%), Positives = 166/489 (33%), Gaps = 60/489 (12%)
Query: 1812 PQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAPPPPPAPSRIPIQDSLSQA 1871
P G G PA + L + P + + S P+AP P P +Q +L
Sbjct: 219 PSAGGGLQRPAS---RSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ-ALRPP 274
Query: 1872 QTSQP--PSPQVFSPGSSN-------SRPPSPMDPYAKMVGTPRPPPVGHSFSRRNSAAP 1922
Q + P + P SS+ S PPSP P + P PP S + + +P
Sbjct: 275 QVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAP-PSLQTLPSPPATPPSQATTSLGSP 333
Query: 1923 VENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTDQFPKSL 1982
T S PL T + P L + P A PP +P + Q P +L
Sbjct: 334 TLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPP-ASPPLSPLATPSPQAPNAL 392
Query: 1983 GLSRSPVVSEQTAKGPIAAGTSDHFTKP-SPRADVFQRQRIPDSYARPLLTPAPLDSGPG 2041
+ P+ A S + P SP A P S A P L PL P
Sbjct: 393 AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT-------PPSQAPPSLAAPPLQVPPS 445
Query: 2042 PFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLTP 2101
P +P P ++ P QA L+ P + P Q+ + PPL
Sbjct: 446 PPASPPMSPSATPPP-----QAPPPLAAPPLQLAKPPP---------QAPPALATPPLQA 491
Query: 2102 HPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQ 2161
P+ SF P +A P S P S P + PP PV+ + P Q
Sbjct: 492 LPSPPASF--PGQAPFSPSA-SLPMS--PLATPPPQAPPVLAA-------------PLLQ 533
Query: 2162 PPGTPRPTTVDPYSQQPQTPRPSTQTD-LFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQ 2220
P +P + ++P TP P T +T P + P + G +
Sbjct: 534 VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHS 593
Query: 2221 PPATPRPRISEGFTRSSMTRPVLMPNQDPFLQA----AQNRGPALPGPLVRPPDTCSQTP 2276
AT P G+ P D L A A +RGPA P P P
Sbjct: 594 SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWP 653
Query: 2277 RPPGPGLSD 2285
GPG +D
Sbjct: 654 PATGPGSAD 662
Score = 71.6 bits (174), Expect = 2e-11
Identities = 115/458 (25%), Positives = 160/458 (34%), Gaps = 87/458 (18%)
Query: 1878 SPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPLQ 1937
+P +PG RPP G+PRPPP PV TP + R L
Sbjct: 16 TPAARAPGLLTPRPP----------GSPRPPP------------PV---TP--AALRVLG 48
Query: 1938 MNETTANRPSPVR--DLCSSSTTNNDPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTA 1995
+P R + ++ + P A P T RP P S R+P ++ T+
Sbjct: 49 AAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP------PASGRGERAPP-AKNTS 101
Query: 1996 KGPIAA-GTSDHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDS--GPGPFKTPMQPPPS 2052
GP+++ G + T+P P R ++ AR T AP S G + P P
Sbjct: 102 PGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG 161
Query: 2053 SQDPYGSVSQASRRLSVD---PYERPALTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESF 2109
+ P ++++ SR + P P+ PRP P P +V+ +
Sbjct: 162 TPSP--AMARRSRAAGTEVGLPRPAPSARPRP---------------PTEGPRKSVSSAS 204
Query: 2110 AHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPT 2169
H S P RP++ +P R + S + S ARS P P+
Sbjct: 205 EH-STTEPSPAARRRPSAGGGLQRP--ASRSLSSSATPLSSPARSGPSARGTPRAPAHPS 261
Query: 2170 TVDPYSQQPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYS-----QPPAT 2224
P Q P T P S P A P + P S P S PPAT
Sbjct: 262 QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPAT 321
Query: 2225 PRPRISEGF-------TRSSMTRPVLMPNQDPFLQAAQNRGPAL--------PGPLVRPP 2269
P + + T S + P L P P QA PAL P P PP
Sbjct: 322 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP----PALALPPLQAPPSPPASPP 377
Query: 2270 DTCSQTPRPPGPGLSDTFSRVSP-SAARDPYDQSPMTP 2306
+ TP P P +P S P Q+P +P
Sbjct: 378 LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 415
Score = 55.5 bits (132), Expect = 1e-06
Identities = 88/374 (23%), Positives = 128/374 (34%), Gaps = 33/374 (8%)
Query: 1799 SDTPSSGIQSPLTPQ--PGNGNMSPAQS--FHKELFTKQPPSTPTSTSSDDVFVKPQAPP 1854
S G+Q+ PQ P + +PA L T P + P+ ++ + P P
Sbjct: 261 SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPA 320
Query: 1855 PPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKM--VGTPRPPPVGH 1912
PP+ + + QA S PSP P S + PP P + + P PP
Sbjct: 321 TPPSQATTSLGSPTLQATHSFLPSP----PLSPLATPPPQAPPALALPPLQAPPSPPASP 376
Query: 1913 SFSRRNSAAP-VENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPR 1971
S + +P N + + P + PSP S P A PP +P
Sbjct: 377 PLSPLATPSPQAPNALAVHLLQAPF------SPPPSPPVQAPFS------PPASPPVSPS 424
Query: 1972 PVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYARPLL 2031
Q P SL V A P++ + P P A + P A P L
Sbjct: 425 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL 484
Query: 2032 TPAPLDSGPGPFKTPMQPPPSSQDPYG-SVSQASRRLSVDPYERPALTPRPIDNFSHNQS 2090
PL + P P P P Q P+ S S L+ P + P + P+ +
Sbjct: 485 ATPPLQALPSP---PASFP--GQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 539
Query: 2091 NDPYSQPP-LTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQSS 2149
P Q P P P + S + P + P S+ P S G P + +S S+
Sbjct: 540 ASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG---PDLAGHSSSA 596
Query: 2150 GTARSNTDPYSQPP 2163
+ Y P
Sbjct: 597 TSTPEELRGYDSGP 610
Score = 54.7 bits (130), Expect = 2e-06
Identities = 84/318 (26%), Positives = 111/318 (34%), Gaps = 53/318 (16%)
Query: 1792 HLLVQSGSDTPSSGIQSPLTPQ---PGNGNMSPAQSFHKELFT---KQPPSTPTSTS-SD 1844
HLL S PS +Q+P +P P + + +P L + PPS P S S
Sbjct: 395 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 454
Query: 1845 DVFVKPQAPPP---------------PPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNS 1889
PQAPPP PPA + P+Q PSP PG +
Sbjct: 455 SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQ---------ALPSPPASFPGQAPF 505
Query: 1890 RPPS--PMDPYAKMVGTPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPS 1947
P + PM P A P+ PPV AAP+ P S LQ P+
Sbjct: 506 SPSASLPMSPLA--TPPPQAPPV--------LAAPLLQVPPSPPASPTLQ---APRRPPT 552
Query: 1948 PVRDLCSSS---TTNNDPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTS 2004
P D S T P PP + P T P G S S + + +G +
Sbjct: 553 PGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 612
Query: 2005 DHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDSGPG-PFKTPMQPPPSSQDPYGSVSQA 2063
P P A++ P +++R P PG P P P S D ++ +
Sbjct: 613 GAAASPPPDAELAACH--PAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYET 670
Query: 2064 SRRLSVDPYERPALTPRP 2081
S P AL P P
Sbjct: 671 EGPESATP-APGALDPGP 687
Score = 50.4 bits (119), Expect = 4e-05
Identities = 35/115 (30%), Positives = 46/115 (40%), Gaps = 10/115 (8%)
Query: 3276 APPTMMPSVQP-QPPLIPGATPPTMSQPTFPMVPQQLQHQQHTTVISGHTSPVRM----- 3329
APP +P P PP+ P ATPP + P P QL + T P++
Sbjct: 437 APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPP 496
Query: 3330 PSLPGWQPNSAPAHLPLN----PPRIQPPIAQLPIKTCTPAPGTVSNANPQSGPP 3380
S PG P S A LP++ PP PP+ P+ P+P PP
Sbjct: 497 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPP 551
Score = 44.3 bits (103), Expect = 0.003
Identities = 37/116 (31%), Positives = 48/116 (41%), Gaps = 12/116 (10%)
Query: 3270 QQQCAMAPPTMMP--SVQPQPPLIPGATPPTMSQPTFPMVPQQLQHQQHTTVISGHTSPV 3327
Q ++ PT+ S P PPL P ATPP + P + P Q + S SP+
Sbjct: 325 QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQ---APPSPPASPPLSPL 381
Query: 3328 RMPSLPGWQPNSAPAHL---PLNPPRIQPPIAQLPIKTCTPAPGTVSNANPQSGPP 3380
PS PN+ HL P +PP PP+ Q P P + S P PP
Sbjct: 382 ATPSPQA--PNALAVHLLQAPFSPPP-SPPV-QAPFSPPASPPVSPSATPPSQAPP 433
Score = 38.5 bits (88), Expect = 0.17
Identities = 71/303 (23%), Positives = 99/303 (32%), Gaps = 56/303 (18%)
Query: 3894 LSNPPTPPASLPPTPPPMACQKMANGFATTEELAGKAGVLVSHEVTKTLGP---KPFQLP 3950
L PP+PPAS P +P AT A A L H + P P Q P
Sbjct: 366 LQAPPSPPASPPLSP-----------LATPSPQAPNA--LAVHLLQAPFSPPPSPPVQAP 412
Query: 3951 FRPQDDLLARALAQGPKTVDVPASLPTPPHNNQEELRIQDHCGDRDTPDSFVPSSSPESV 4010
F P A P P SL PP ++ +P + P +P +
Sbjct: 413 FSPPASPPVSPSATPPS--QAPPSLAAPP----LQVPPSPPASPPMSPSATPPPQAPPPL 466
Query: 4011 VGVEVSRYPDLSLVKEEP--PEPVPSPIIPILPSTAGKSSESRRNDIKTEPGTLYFASPF 4068
P L L K P P + +P + LPS P + +PF
Sbjct: 467 AA------PPLQLAKPPPQAPPALATPPLQALPS---------------PPASFPGQAPF 505
Query: 4069 GPSPNGPRSGLISVAITLHPTAAENISSVVAAFSDLLHVRIPNSYEVSSAPDVPSMGLVS 4128
PS + P S L + P A + V + ++ P + PD G
Sbjct: 506 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR-PPTPGPDTSVSGPRL 564
Query: 4129 SHRINPGLEYRQHLLLRGPPPGSANPPRLVSSYRLKQPNVPFPPTSNGLSGYKDSSHGIA 4188
+ + PG PPP S +P +S L + T L GY G A
Sbjct: 565 TLALAPG----------PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGA 614
Query: 4189 ESA 4191
++
Sbjct: 615 AAS 617
Score = 38.1 bits (87), Expect = 0.22
Identities = 104/459 (22%), Positives = 148/459 (32%), Gaps = 77/459 (16%)
Query: 2253 AAQNRGPALPGPLV-RPPDTCSQTPRPPGPGLSDTFSRVSPSAARDPYDQSPMTPRSQSD 2311
AA+ PG L RPP + PRPP P V+P+A R + + ++
Sbjct: 13 AARTPAARAPGLLTPRPPGS----PRPPPP--------VTPAALRVLGAAGAVGRKPLAE 60
Query: 2312 SFGTSQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQL-PGPVPTSG-VTDTQN 2369
G A PR G +S P +G++ PGPV + G + T
Sbjct: 61 RAGGIGGATIPESAPRAGPT----RTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR 116
Query: 2370 TVNMAQADTEKLRQRQKLREIILQQQQQKKI-AGRQEKGSQDSPAVPHPGPLQHWQPENV 2428
+ Q + R + ++ + AG + S +P P P + +
Sbjct: 117 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT 176
Query: 2429 NQAFTRPPPPYPGNIRSPVAPPLGPRYAVFPKDQRGPYPPD---------------VASM 2473
RP P P P GPR +V + P AS
Sbjct: 177 EVGLPRPAPS-----ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 231
Query: 2474 GMRPHGFRFGFPGGSHGTMPSQERFLVPPQQIQGSGVSPQLRRSVSVDMPR--------P 2525
+ P S + R P Q + G+ Q R V PR P
Sbjct: 232 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGL--QALRPPQVTPPRKDAAPALGP 289
Query: 2526 LNNSQM--NNPVGLPQHFSPQSL----------PVQQHNILGQAYIELRHRAPDGRQRLP 2573
L++S + +P P +P SL P Q LG ++ H P
Sbjct: 290 LSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP 349
Query: 2574 FSAPPGSVVEASSNLRHGNFIPRPDFPGPRHTDPMRRPPQGLPNQLPVHPDLEQV----P 2629
+ PP +A L P P P+ P PN L VH L Q P
Sbjct: 350 LATPP---PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH--LLQAPFSPP 404
Query: 2630 PSQQEQG-HSVHSSSMVMRTLNHPLGGEFSEAPLSTSVP 2667
PS Q S +S V + P S+AP S + P
Sbjct: 405 PSPPVQAPFSPPASPPVSPSATPP-----SQAPPSLAAP 438
Score = 32.7 bits (73), Expect = 9.1
Identities = 40/151 (26%), Positives = 56/151 (37%), Gaps = 17/151 (11%)
Query: 1461 IGPVTDDPSSLPQPNVNQSSRPLSEEQLDGILSPELDKMVTDGAILGKLYKIPELGGKDV 1520
+GP++ P + P P+ S P + L + SP LG P L
Sbjct: 287 LGPLSSSPLATPSPSAPPS--PSAPPSLQTLPSPPATPPSQATTSLGS----PTLQATH- 339
Query: 1521 EDLFTAVLSPANTQPTPLPQPPPPTQLLPIHNQDAFSRMPLMNGLIGSSPHLPHNSLPPG 1580
L + LSP T P PQ PP L P+ + P ++ L SP P
Sbjct: 340 SFLPSPPLSPLATPP---PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP------- 389
Query: 1581 SGLGTFSAIAQSSYPDARDKNSAFNPMASDP 1611
+ L A S P + + F+P AS P
Sbjct: 390 NALAVHLLQAPFSPPPSPPVQAPFSPPASPP 420
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 83.6 bits (205), Expect = 5e-15
Identities = 164/691 (23%), Positives = 236/691 (34%), Gaps = 121/691 (17%)
Query: 1796 QSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPTSTSSDDVFVKPQAPPP 1855
Q S T S+ + P PQ G+G SP+ E + S V ++ PP
Sbjct: 441 QPESSTASNSVVPP--PQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPP 498
Query: 1856 PPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFS 1915
PP P R SL Q + P P P + P PRPP G S
Sbjct: 499 PP-PRRT---HSLHQRGLAVPDGPLGLPPKPERKQQPQ----------LPRPPTTGGSEG 544
Query: 1916 RRNSAAP-------VENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNNDPYAKPPD 1968
+ P V +P S RP + E T + S + T A PP
Sbjct: 545 AGAAPCPPNPANSWVPGLSPGGS-RRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPA 603
Query: 1969 TPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTKPSPRADVFQRQRIPDSYAR 2028
+P + P+ + RSP S ++ + + +SD PS R+ + D +
Sbjct: 604 SPGKAQPPK-PERVTSLRSPGASVSSSLTSLCSSSSD--PAPSDRSGPQILTPLGDRFVI 660
Query: 2029 PLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQASRRLSVDPYERPALTPRPIDNFSHN 2088
P P P PF PPPS S + A+ L+ PA+ P P+ +
Sbjct: 661 P-----PHPKVPAPFS----PPPSKPR---SPNPAAPALAA-----PAVVPGPVSTTDAS 703
Query: 2089 QSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQS 2148
+ P Q LTP + ES P + Q S P S P P P VV++ S S
Sbjct: 704 PQSPPTPQTTLTP---LQES---PVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSAS 757
Query: 2149 SGTARSNTDPYSQPPGTPRPTTVD------PYSQQ-------PQTPRPSTQTDLFVTPVT 2195
DP PP P P D P ++ P+ PS +L +P
Sbjct: 758 ETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAA 817
Query: 2196 NQRHSDP-YAHPPGTPRPGISVPYSQPPATPRPRISEGFTRSSMTRPVLMPNQDPFLQAA 2254
+ + PPG+P P PPA P P + S+ +P ++P + +
Sbjct: 818 SSSSATALQIQPPGSPDP--------PPAPPAPAPAS----SAPGHVAKLPQKEP-VGCS 864
Query: 2255 QNRGPA---LPGPLVRPPDTCSQTPRPPG-PGLSDTFSRVSPSAARDPYDQ------SPM 2304
+ GP + PLV P R G PG + T + PSA + P + SP+
Sbjct: 865 KGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPT-PALGPSAPQKPLRRALSGRASPV 923
Query: 2305 TPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTSGV 2364
S A +A SEG A N P ++ P P
Sbjct: 924 PAPSSGLHAAVRLKACSLA-----ASEGLSSAQPNGPPEAE------------PRPPQSP 966
Query: 2365 TDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKKIAGRQEKGSQDSPAVPHPGPLQHWQ 2424
T + + + KL+ + + Q+ +A + Q P P P
Sbjct: 967 ASTASFI--FSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSP----- 1019
Query: 2425 PENVNQAFTRPPPPYPGNIRSPVAPPLGPRY 2455
+ PPP V PP P Y
Sbjct: 1020 ---------KAPPPVARKPSVGVPPPASPSY 1041
Score = 58.9 bits (141), Expect = 1e-07
Identities = 133/558 (23%), Positives = 183/558 (32%), Gaps = 125/558 (22%)
Query: 1833 QPPSTPTSTSSDDVFVKPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPGSSNSRPP 1892
Q P PT+ S+ P PP PA S +P LS + +PP S R
Sbjct: 532 QLPRPPTTGGSEGAGAAPC--PPNPANSWVP---GLSPGGSRRPPR--------SPERTL 578
Query: 1893 SPMDPYAKMVGTPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDL 1952
SP Y+ GTP PP G + A+P + P R + A+ S + L
Sbjct: 579 SPSSGYSSQSGTPTLPPKGLAGP---PASPGKAQPP--KPERVTSLRSPGASVSSSLTSL 633
Query: 1953 CSSSTTNNDPYAKPPDTPRPVMTDQF-----PKSLGLSRSPVVSEQTAKGPIAAGTSDHF 2007
CSSS+ P P + D+F PK + SP S+ + P A +
Sbjct: 634 CSSSSDPAPSDRSGPQILTP-LGDRFVIPPHPK-VPAPFSPPPSKPRSPNPAAPALAAPA 691
Query: 2008 TKPSPRADVFQRQRIPDSYARPLLTPAPLDSGPGPFKT---PMQPPPSSQDP-------- 2056
P P V P S P T PL P K P PPPS P
Sbjct: 692 VVPGP---VSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPE 748
Query: 2057 ----YGSVSQASRRLSVDPYERPALTPRPID----------------NFSHNQSNDPYSQ 2096
S S+ + DP P P P + + + + P
Sbjct: 749 VVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGS 808
Query: 2097 PPLTPHPAVNESFAH------------------PSRAFSQPGTISRPTSQDPY--SQPPG 2136
P L PA + S A P+ A S PG +++ ++P S+ G
Sbjct: 809 PELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGG 868
Query: 2137 TPR-----PVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQP--------QTPRP 2183
PR P+V RS P G P P Q+P +P P
Sbjct: 869 PPREDVGAPLVTPSLLQMVRLRS----VGAPGGAPTPALGPSAPQKPLRRALSGRASPVP 924
Query: 2184 STQTDLF---------VTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFT 2234
+ + L + + P P PRP S P +T S+G
Sbjct: 925 APSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQS-----PASTASFIFSKGSR 979
Query: 2235 RSSMTRPVLMPNQDPFLQAAQNRGPALPGPLV---RPPDTCSQTPRPPGPGLSDTFSRVS 2291
+ + RPV P QA R + RPP ++P+ P P V
Sbjct: 980 KLQLERPV-----SPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVP 1034
Query: 2292 PSAARDPYDQSPMTPRSQ 2309
P A SP PR++
Sbjct: 1035 PPA-------SPSYPRAE 1045
Score = 46.6 bits (109), Expect = 6e-04
Identities = 71/297 (23%), Positives = 111/297 (37%), Gaps = 36/297 (12%)
Query: 3513 PSFVPDSPSIPVGSPNFS-SVKQGHGNLSGTSFQQSPVRPSFTPALPAAPPVANSSLPCG 3571
P P P SP + S G+ + SGT + P PA+P A P
Sbjct: 560 PGLSPGGSRRPPRSPERTLSPSSGYSSQSGTP----TLPPKGLAGPPASPGKAQPPKPER 615
Query: 3572 QDSTITHGHSYPGSTQSLIQLYSDIIPEEK-GKKKRTRKKKRDDDAESTKAPSTPHSDIT 3630
S + G S S SL SD P ++ G + T R K P+ +
Sbjct: 616 VTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAP----FS 671
Query: 3631 APPTPGISETTSTPAVSTPSELPQQADQESVEPVGPSTPNMAAGQLCTELENKLPNSDFS 3690
PP+ S + PA++ P+ +P P P TP L E+ + + D S
Sbjct: 672 PPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPL---QESPVISKDQS 728
Query: 3691 QATPNQQTY----ANSEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVEG 3746
+Y ++ ++ +E P+ +E + E + + P P EEQ+
Sbjct: 729 PPPSPPPSYHPPPPPTKKPEVVVEAPSASETAE-EPLQDPNWPPPPPPAPEEQD------ 781
Query: 3747 NAVACPVSSAQSPP-----HSAGAPAAKGDSGN-ELLKHLLKNKKSSSLLNQKPEGS 3797
+S A PP S +P G SG+ EL+ + S++ L +P GS
Sbjct: 782 ------LSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGS 832
Score = 39.7 bits (91), Expect = 0.075
Identities = 89/409 (21%), Positives = 135/409 (33%), Gaps = 76/409 (18%)
Query: 3277 PPTMMPSVQPQPP------LIPGATPPTMSQPTFPMVPQQ-LQHQQHTTVISGHTSPVRM 3329
PP+ S P P ++PG T + P P PQ L Q + VIS SP
Sbjct: 673 PPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSP--- 729
Query: 3330 PSLPGWQPNSAPAHLPLNPPRIQPPIAQLPIKTCTPAPGTVSNANPQSGPPPRVEFDDNN 3389
P+ P++ P PP +P + A + + N PPP
Sbjct: 730 ------PPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPA------- 776
Query: 3390 PFSESFQERERKERLREQQERQRIQLMQEVDRQRALQQRMEMEQHGMVGS--------EI 3441
E Q + + + A E G GS
Sbjct: 777 ------------------PEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAAS 818
Query: 3442 SSSRTSVSQIPFYSSDLPCDFMQPLGPLQQSPQHQQQMGQVLQQQNIQQG------SINS 3495
SSS T++ P S D P P P +P H ++ Q + +G + +
Sbjct: 819 SSSATALQIQPPGSPDPPPAPPAP-APASSAPGHVAKLPQ-KEPVGCSKGGGPPREDVGA 876
Query: 3496 P-STQTFMQTNERRQVGPPSFVPDSPSIPVGSPNFSSVKQGHGNLSGTSFQQSPVRPS-- 3552
P T + +Q R VG P P +P++ +P + G S S + +
Sbjct: 877 PLVTPSLLQMVRLRSVGAPGGAP-TPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVR 935
Query: 3553 -----------FTPALPAAPPVANSSLPCGQDSTITHGHSYPGSTQSLIQLYSDIIPEEK 3601
+ A P PP A P ST + S GS + +QL + PE +
Sbjct: 936 LKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFS-KGSRK--LQLERPVSPETQ 992
Query: 3602 GKKKRTRKKKRDDDAESTKAPSTPHSDITAPPTPGISETTSTPAVSTPS 3650
+R + +E + P P APP + P ++PS
Sbjct: 993 ADLQRNLVAELRSISEQ-RPPQAPKKSPKAPPPVARKPSVGVPPPASPS 1040
Score = 35.8 bits (81), Expect = 1.1
Identities = 39/158 (24%), Positives = 54/158 (34%), Gaps = 45/158 (28%)
Query: 3895 SNPPTPPASLPPTPPPMACQKMANGFATTEELAGKAGVLVSHEVTKTLGPKPFQLPFRPQ 3954
S PP+PP S P PPP K V+V +P Q P P
Sbjct: 728 SPPPSPPPSYHPPPPPTK----------------KPEVVVEAPSASETAEEPLQDPNWPP 771
Query: 3955 DDLLARALAQGPKTVDVPASLPTPPHNNQEELRIQDHCGDRD------TPDSFVPSSSPE 4008
P PP +++L + D + +P+ PS SPE
Sbjct: 772 ---------------------PPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPE 810
Query: 4009 SVVGVEVSRYPDLSLVKEEP--PEPVPSPIIPILPSTA 4044
V S +L + P P+P P+P P S+A
Sbjct: 811 LVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSA 848
Score = 34.7 bits (78), Expect = 2.4
Identities = 116/488 (23%), Positives = 164/488 (33%), Gaps = 78/488 (15%)
Query: 2188 DLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQP-PATPRPRISEGFTRSSMTRP--VLM 2244
D FV T R + P P PG++ P +P IS T S P VL
Sbjct: 303 DTFVGRSTGTR-APPLTRPMSLAVPGLTGGAGPAEPLSPAMSISPQATYLSKLIPHAVLP 361
Query: 2245 PNQDPFLQ-----------AAQNRGPALPGPLVRPPDTCSQTPRPPGP-GLSDTFSRVSP 2292
P D + + PA L R S PR P SDT+S S
Sbjct: 362 PTVDVVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSH-SQ 420
Query: 2293 SAARDPYDQSPMTPRSQSDSFGTSQTAHDVADQPRPG-------SEGSFCASSNSPMHSQ 2345
S+ D S ++ + S+ S TA + P G S GS +S++
Sbjct: 421 SSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRS 480
Query: 2346 GQQFSGVS----QLPGPVPTSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKKIA 2401
Q SG S +L P P T + + +A D + R+ Q +
Sbjct: 481 SGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTG 540
Query: 2402 GRQEKGSQDSPAVPHPGPLQHWQPENVNQAFTRPPPPYPGNIRSP--------------- 2446
G + G+ P P P W P ++ +R PP P SP
Sbjct: 541 GSEGAGAAPCP----PNPANSWVP-GLSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPP 595
Query: 2447 ---VAPPLGPRYAVFPKDQ-----RGPYPPDVASMGMRPHGFRFGFPGGSHGTM---PSQ 2495
PP P A PK + R P +S+ P G P
Sbjct: 596 KGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLG 655
Query: 2496 ERFLVPPQQIQGSGVS--PQLRRSVSVDMPRPLNNSQMNNPVGLPQHFSPQSLPVQQHNI 2553
+RF++PP + S P RS + P + + PV SPQS P Q +
Sbjct: 656 DRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTD-ASPQSPPTPQTTL 714
Query: 2554 --LGQAYIELRHRAPDGRQRLPFSAPPGS------VVEASS-------NLRHGNFIPRPD 2598
L ++ + + ++P + PP VVEA S L+ N+ P P
Sbjct: 715 TPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPP 774
Query: 2599 FPGPRHTD 2606
P P D
Sbjct: 775 -PAPEEQD 781
Score = 34.3 bits (77), Expect = 3.1
Identities = 37/135 (27%), Positives = 49/135 (36%), Gaps = 23/135 (17%)
Query: 3278 PTMMPSVQPQPPLIPG-ATPPTMSQPTFPMVPQQLQHQQHTTVISGHTSPVRMPS----- 3331
PT+ P PP PG A PP + T P T++ S + P PS
Sbjct: 591 PTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPA--PSDRSGP 648
Query: 3332 -----------LPGWQPNSAPAHLPLNPPRIQPPIAQ-LPIKTCTPAPGTVSNANPQSGP 3379
+P AP P + PR P A L P P + ++A+PQS P
Sbjct: 649 QILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPP 708
Query: 3380 PPRVEFDDNNPFSES 3394
P+ P ES
Sbjct: 709 TPQTTL---TPLQES 720
Score = 33.5 bits (75), Expect = 5.3
Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 7/53 (13%)
Query: 2910 GITGSTPVLSSLLANEKSDNS-DIRPSGSPPPPTLPASPS------NHVSSLP 2955
G +GS ++SS A+ S + I+P GSP PP P +P+ HV+ LP
Sbjct: 804 GPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLP 856
Score = 33.1 bits (74), Expect = 7.0
Identities = 62/312 (19%), Positives = 94/312 (30%), Gaps = 55/312 (17%)
Query: 3858 GEKAAPRSKKRKKDEEEKQAMYSSTDTFTHLKQQNNLSNPPTPPASLPPTPPPMACQKMA 3917
G + PRS +R + S T T L+ PP P P P +
Sbjct: 566 GSRRPPRSPERTLSPSSGYSSQSGTPTLP----PKGLAGPPASPGKAQPPKPERVTSLRS 621
Query: 3918 NGFATTEELAGKAGVLVSHEVTKTLGPK-------PFQLPFRPQDDLLARALAQGPKTVD 3970
G + + L + GP+ F +P P+ P++ +
Sbjct: 622 PGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPN 681
Query: 3971 -------VPASLPTPPHNNQEELRIQDHCGDRDTPDSFVPSSSPESVVGVEVSRYPDLSL 4023
PA +P P + TP + + V+ + S P
Sbjct: 682 PAAPALAAPAVVPGPVSTTDASPQ------SPPTPQTTLTPLQESPVISKDQSPPPSPPP 735
Query: 4024 VKEEPPEPVPSPIIPILPSTAGKSSESRRNDIKTEPGTLYFASPFGPSPNGPRSGLISVA 4083
PP P P + + +A +++E D P P P P +S+A
Sbjct: 736 SYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPP----------PPPPAPEEQDLSMA 785
Query: 4084 ITLHPTAAENISSVVAAFSDLLHVRIPNSYEVSSAPDVPSMGLVSSHRINPGLEYRQHLL 4143
P A V P S +P+ LVSS P
Sbjct: 786 DFPPPEEA------------FFSVASPEPAGPSGSPE-----LVSS----PAASSSSATA 824
Query: 4144 LRGPPPGSANPP 4155
L+ PPGS +PP
Sbjct: 825 LQIQPPGSPDPP 836
>gi|119943102 CREB binding protein isoform b [Homo sapiens]
Length = 2404
Score = 82.4 bits (202), Expect = 1e-14
Identities = 157/622 (25%), Positives = 224/622 (36%), Gaps = 125/622 (20%)
Query: 2112 PSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTV 2171
PS + PGT ++ S QPP P+P S S + + + T QPP T +T
Sbjct: 1845 PSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVART----QPPTT--VSTG 1898
Query: 2172 DPYSQQPQTPRPSTQTDLFVTPVTN-QRHSDPYAH----------PPGTPRPGISVPYSQ 2220
P SQ P P P+ V +R + H PPG R G+ P SQ
Sbjct: 1899 KPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPG--RTGMGTPGSQ 1956
Query: 2221 PPA----TPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTP 2276
PRP G SM P Q P Q Q P LP P++ +
Sbjct: 1957 MAPVSLNVPRPNQVSGPVMPSM--PPGQWQQAPLPQ--QQPMPGLPRPVI-SMQAQAAVA 2011
Query: 2277 RPPGPGLSDTFSRVSPSAARDPYD--QSPMTPRSQSD-------------SFGTSQTAHD 2321
P P + S +SPSA +D +SP +P+ Q +F +TA
Sbjct: 2012 GPRMPSVQPPRS-ISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKY 2070
Query: 2322 VAD----QPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQNTVNMAQAD 2377
VA+ QP+PG + MH Q ++ + VP GV Q +
Sbjct: 2071 VANQPGMQPQPGLQSQPGMQPQPGMHQQ-PSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQ 2129
Query: 2378 TEKL----------------RQRQKLREIILQQQQQKKIAGRQEKGSQDSPAVPHPGPLQ 2421
+ L + R+ LR +LQQQQQ++ +Q++ Q A G
Sbjct: 2130 GQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAG 2189
Query: 2422 HWQPENVNQAFTRPPPPYPGNIRSPVAPPLGPRYAVFPKDQRGPYPPDV-ASMGMRPHGF 2480
H Q F +P P G YPP + M+ H
Sbjct: 2190 HGQ-------FQQPQGP-------------------------GGYPPAMQQQQRMQQH-- 2215
Query: 2481 RFGFPGGSHGTMPSQERFL-VPPQQIQGSGVSPQLRRSVSVDMPRPLNNSQMNNPVGLPQ 2539
G S G M +Q L Q G+ +P +++++ R L QM +G P
Sbjct: 2216 -LPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQAL---QQRILQQQQMKQQIGSPG 2271
Query: 2540 HFSPQSLPVQQHNILGQ---AYIELRHRAPDGRQRLPFSAPPGSVVEASSNLRHGNFIPR 2596
+P S QQH + GQ +++ + A ++ AP S S H + PR
Sbjct: 2272 QPNPMS--PQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQS-PRPQSQPPHSSPSPR 2328
Query: 2597 -PDFPGPRHTDPMRRPPQGLPNQLPVHPDLEQVPPSQQEQGHSVH-SSSMVMRTLNHPLG 2654
P P H P P HP L S +QGH + S ++ LN P
Sbjct: 2329 IQPQPSPHHVSPQTGSP---------HPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSR 2379
Query: 2655 GEFSEAPLSTSVPSETTSDNLQ 2676
S S+ +TT D L+
Sbjct: 2380 SALSS---ELSLVGDTTGDTLE 2398
Score = 58.2 bits (139), Expect = 2e-07
Identities = 89/331 (26%), Positives = 123/331 (37%), Gaps = 50/331 (15%)
Query: 3242 SMVQKQLEQIRKQQKEHAELIEDYRIKQQQQCAMAPPTMMPSVQPQPPLIPGATPPTMSQ 3301
SM Q +Q Q++ + I Q Q A+A P M PSVQP + P A +
Sbjct: 1977 SMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRM-PSVQPPRSISPSALQDLLRT 2035
Query: 3302 PTFPMVPQQLQH---------QQHTTVISGHTSPVRMPSLPGWQPN----SAPAHLPLNP 3348
P PQQ Q Q I T+ + + PG QP S P P
Sbjct: 2036 LKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKY-VANQPGMQPQPGLQSQPGMQPQPG 2094
Query: 3349 PRIQPPIAQL-PIKTCTPAPGT------VSNANPQSGPPPRVEFDDNNPFSESFQERERK 3401
QP + L ++ P PG + NPQ G + +NP S + R
Sbjct: 2095 MHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQ-GQALNIMNPGHNPNMASMNPQYR- 2152
Query: 3402 ERLREQQERQRIQLMQEVDRQRALQQRMEMEQHGMVGSEISSSRTSVSQIPFYSSDLPCD 3461
E R QL+Q+ +Q+ QQ+ + +Q G G ++ Q
Sbjct: 2153 -------EMLRRQLLQQQQQQQQQQQQQQQQQQGSAG--MAGGMAGHGQ----------- 2192
Query: 3462 FMQPLGPLQQSPQHQQQMGQVLQQQNIQQGSINSPSTQTFMQTNERRQVGPPSFVPDS-P 3520
F QP GP P QQQ Q +QQ QG S Q Q + Q+G P DS P
Sbjct: 2193 FQQPQGPGGYPPAMQQQ--QRMQQHLPLQG---SSMGQMAAQMGQLGQMGQPGLGADSTP 2247
Query: 3521 SIPVGSPNFSSVKQGHGNLSGTSFQQSPVRP 3551
+I +Q G+ Q +P+ P
Sbjct: 2248 NIQQALQQRILQQQQMKQQIGSPGQPNPMSP 2278
Score = 55.8 bits (133), Expect = 1e-06
Identities = 94/408 (23%), Positives = 140/408 (34%), Gaps = 87/408 (21%)
Query: 3365 PAPGTVSNANPQSGP--PPRVEFDDNNPFSESFQERERKERLREQQERQ--RIQLMQEVD 3420
PAPG PQ+ P PP N P S + + + +QL Q
Sbjct: 648 PAPGAQPPVIPQAQPVRPP------NGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPM 701
Query: 3421 RQRA---LQQRMEMEQHGMV-GSEISSSR-------------TSVSQIPFYSSDLPCD-F 3462
RA + ++M G V G IS SR ++Q P S LP + F
Sbjct: 702 GPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQF 761
Query: 3463 MQPLGPLQQSPQHQQQMGQVLQQQNIQQGSINSPSTQTFMQTNERRQVGPPSFVPDSPSI 3522
G + MGQ Q + QG + + N +GP + P
Sbjct: 762 PSSSGAMSVG------MGQPPAQTGVSQGQVPGAALP-----NPLNMLGPQA--SQLPCP 808
Query: 3523 PVGSPNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAAP-----PVANSSLPCGQDSTIT 3577
PV +G Q P TP PAAP PV++S GQ T T
Sbjct: 809 PVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS----GQTPTPT 864
Query: 3578 HGHSYPGSTQSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTKAPSTPHSDITAPPTPGI 3637
G S P +TQ+ + T + A+ T P TP
Sbjct: 865 PG-SVPSATQT----------------QSTPTVQAAAQAQVTPQPQTP------------ 895
Query: 3638 SETTSTPAVSTPSELPQQADQESVEPVGPSTPNMAAGQLCTELENKLPNSDFSQATPNQQ 3697
P+V+TP Q+ Q+ PV P Q ++N++P +
Sbjct: 896 ---VQPPSVATP-----QSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNS 947
Query: 3698 TYANSEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVE 3745
+V L M+T + E+ + + E++ P E + + Q S+V+
Sbjct: 948 QQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVK 995
Score = 54.7 bits (130), Expect = 2e-06
Identities = 130/579 (22%), Positives = 208/579 (35%), Gaps = 161/579 (27%)
Query: 2892 NVIQASTQLPAQDVINSCGITGSTPVLSSLLANEKSDNSDIRPSGSP------PPPTLPA 2945
NV Q S P + STP A + + P+G P PP T+
Sbjct: 1838 NVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVST 1897
Query: 2946 S-PSNHVSSLPPFIAPPGRVLDNAMNSNVTVVSRVNHVFSQGVQVNPGLIPGQSTVNHSL 3004
P++ V + PP PP ++ A + H++ V +N + PG++
Sbjct: 1898 GKPTSQVPAPPPPAQPPPAAVEAARQIE-REAQQQQHLYR--VNINNSMPPGRT------ 1948
Query: 3005 GTGKPATQTGPQT-SQSGTSSMSGP----------QQLMIPQTLAQQNRERPLLLEE--- 3050
G G P +Q P + + + +SGP QQ +PQ RP++ +
Sbjct: 1949 GMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQA 2008
Query: 3051 ----------------QPLLLQDLL----DQERQEQQQQ---------RQMQAMIRQRSE 3081
P LQDLL +QQQQ + M A I+QR+
Sbjct: 2009 AVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTA 2068
Query: 3082 PFFPNIDFDAITDPIMKAK--MVALKGINKVMAQNNL----------GMPPMVMSRFPFM 3129
+ N P ++++ M G+++ + NL G+PP
Sbjct: 2069 KYVAN-QPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQ-------- 2119
Query: 3130 GQVVTGTQNSEGQNLGPQAIPQDGSITHQISRPNPPNFGPGFVNDSQRKQYEEWLQETQQ 3189
Q G N +GQ L +I + PN + P + + R+Q LQ+ QQ
Sbjct: 2120 -QQAMGGLNPQGQAL---------NIMNPGHNPNMASMNPQY-REMLRRQL---LQQQQQ 2165
Query: 3190 LLQMQQKYLEEQIGAHRKSKKALSAKQRTAKKAGREFP---EEDAEQLKHVTEQQSMVQK 3246
Q QQ+ ++Q G+ + Q + +P ++ +H+ Q S + +
Sbjct: 2166 QQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQ 2225
Query: 3247 QLEQIRK-----------------QQKEHAELIEDYRIKQQ-----QQCAMAPPTMMPSV 3284
Q+ + QQ +++ ++KQQ Q M+P M S
Sbjct: 2226 MAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSG 2285
Query: 3285 QPQPPLIPGATPPTMSQPTFPMVPQQLQHQQHTTVISGHT---SPVRMPSLPGWQPNSAP 3341
QPQ +PG QQ T +S +PV+ P P+S+P
Sbjct: 2286 QPQASHLPG--------------------QQIATSLSNQVRSPAPVQSPRPQSQPPHSSP 2325
Query: 3342 AHLPLNPPRIQPPIAQLPIKTCTPAPGTVSNANPQSGPP 3380
+ PRIQP P+P VS PQ+G P
Sbjct: 2326 S------PRIQP----------QPSPHHVS---PQTGSP 2345
Score = 53.9 bits (128), Expect = 4e-06
Identities = 114/486 (23%), Positives = 166/486 (34%), Gaps = 68/486 (13%)
Query: 1770 TQKLEQVKNEQ--QQQQQQQFGSQHLLVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHK 1827
TQ QV +Q Q Q QQ + + L + + P+ GI + P N+ +
Sbjct: 460 TQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQQPP----NLISESALPT 515
Query: 1828 ELFTKQPPSTPTSTSSD--DVFVKPQAPPPPPAPSRIPIQDSLSQAQTSQP--------- 1876
L P S S + + P A PP R + ++Q S
Sbjct: 516 SLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIF 575
Query: 1877 PSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPL 1936
P+P P + R + YAK V G + NS +
Sbjct: 576 PTPD---PAALKDRRMENLVAYAKKVE-------GDMYESANSRDEYYHLLAEKIYKIQK 625
Query: 1937 QMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPR--PVMTDQFPKSLGLSRSPVVSEQT 1994
++ E +R + + + P A+PP P+ PV P SL ++R V
Sbjct: 626 ELEEKRRSRLHK-QGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMN 684
Query: 1995 AKGPIAAGTSDHFTKP-SPRA--------DVFQRQRIPDSYARPLLTPAPLDS-GPGPFK 2044
+ P++ G P PRA + +P P P P + G
Sbjct: 685 SFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNN 744
Query: 2045 TPMQPPPSSQD-PYGSVSQASRRLSVDPYERPALT------------PRPIDNFSHNQSN 2091
Q P SQ P +S +SV + PA T P P++ S
Sbjct: 745 MMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQ 804
Query: 2092 ---DPYSQPPLTPHPAVNESFAH-PSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQ 2147
P +Q PL P P + A PS + P P P P P V S Q
Sbjct: 805 LPCPPVTQSPLHPTPPPASTAAGMPSLQHTTP-----PGMTPPQPAAPTQPSTPVSSSGQ 859
Query: 2148 SSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPST--QTDLFVTPVTNQRHSDP-YA 2204
+ + +Q TP TV +Q TP+P T Q TP ++Q+ P +A
Sbjct: 860 TPTPTPGSVPSATQTQSTP---TVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHA 916
Query: 2205 HPPGTP 2210
PPGTP
Sbjct: 917 QPPGTP 922
Score = 50.1 bits (118), Expect = 6e-05
Identities = 94/420 (22%), Positives = 146/420 (34%), Gaps = 79/420 (18%)
Query: 1826 HKELFTKQPPSTPTSTSSDDVFVKPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPG 1885
HK+ P+ P + V + Q PP P +P+ ++ Q SQ F+P
Sbjct: 636 HKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPV----NRMQVSQ--GMNSFNPM 689
Query: 1886 SSNS--RPPSPMDPYAKMVGTPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTA 1943
S + P +PM P A A+P+ + ++S+ M + +
Sbjct: 690 SLGNVQLPQAPMGPRA--------------------ASPMNHSVQMNSMGSVPGMAISPS 729
Query: 1944 NRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGT 2003
P P + N+ A+ P + + +QFP S G + S + + A+ ++ G
Sbjct: 730 RMPQPPNMM---GAHTNNMMAQAPAQSQFLPQNQFPSSSG-AMSVGMGQPPAQTGVSQGQ 785
Query: 2004 SDHFTKPSPRADVF-QRQRIPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQ 2062
P+P + Q ++P P +T +PL P P T P
Sbjct: 786 VPGAALPNPLNMLGPQASQLP----CPPVTQSPLHPTPPPASTAAGMP------------ 829
Query: 2063 ASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTI 2122
S+ P +TP + Q + P S TP P P S T
Sbjct: 830 -----SLQHTTPPGMTPP--QPAAPTQPSTPVSSSGQTPTPT-------PGSVPSATQTQ 875
Query: 2123 SRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSN----TDPYSQPPGTPRPTTVDPYSQQP 2178
S PT Q +Q TP+P S T +S+ T ++QPPGTP +
Sbjct: 876 STPTVQ-AAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRV 934
Query: 2179 QTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFTRSSM 2238
TP + TN + P P + P P S+G RS M
Sbjct: 935 PTPSSVASAE------TNSQQPG-----PDVPVLEMKTETQAEDTEPDPGESKGEPRSEM 983
Score = 50.1 bits (118), Expect = 6e-05
Identities = 124/611 (20%), Positives = 195/611 (31%), Gaps = 83/611 (13%)
Query: 1780 QQQQQQQQFGSQHLLVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPT 1839
Q + QQ Q + + + + P + SP T PP TPT
Sbjct: 1818 QHRLQQAQLMRRRMATMNTRNVPQQSLPSP---------------------TSAPPGTPT 1856
Query: 1840 STSSDDVFVKPQAPPPPPAPSRIPIQDS----LSQAQTSQPPSPQVFSPGSSNSRPPSPM 1895
S PQ P PP P P+ S S A+T P + P S PP P
Sbjct: 1857 QQPS-----TPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPA 1911
Query: 1896 DPYAKMVGTPRPPPVGHSFSRRNSAAPVENCTP--------LSSVSRPLQMNETTANRPS 1947
P V R + + N P S P+ +N N+ S
Sbjct: 1912 QPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVS 1971
Query: 1948 -PVRDLCSSSTTNNDPYAKP---PDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGT 2003
PV P + P PRPV++ Q ++ R P V + P A
Sbjct: 1972 GPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQD 2031
Query: 2004 SDHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDSGPGPF---KTPMQPPPSSQDPYGSV 2060
T SP + Q+Q + + P L A + + + MQP P Q G
Sbjct: 2032 LLR-TLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQ 2090
Query: 2061 SQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFS--Q 2118
Q +++P+L N + Q+ P +P + P +A +
Sbjct: 2091 PQPGM------HQQPSL-----QNLNAMQAGVP--RPGVPPQQQAMGGLNPQGQALNIMN 2137
Query: 2119 PGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQP 2178
PG S +P + R ++ Q + G QQP
Sbjct: 2138 PGHNPNMASMNPQYREM-LRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQP 2196
Query: 2179 QTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFT---R 2235
Q P + + Q+ + G+ ++ Q +P + T +
Sbjct: 2197 QGPGG------YPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQ 2250
Query: 2236 SSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRP---PGPGLSDTFSRV-- 2290
++ + +L Q Q P P P+ S P+ PG ++ + S
Sbjct: 2251 QALQQRILQQQQ----MKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVR 2306
Query: 2291 SPSAARDPYDQSPMTPRSQSDSFGTSQTAHDVADQ---PRPGSEGSFCASSNSPMHSQGQ 2347
SP+ + P QS S S + H V+ Q P PG + +S + +
Sbjct: 2307 SPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPE 2366
Query: 2348 QFSGVSQLPGP 2358
Q + + QL P
Sbjct: 2367 QSAMLPQLNTP 2377
Score = 45.1 bits (105), Expect = 0.002
Identities = 70/314 (22%), Positives = 110/314 (35%), Gaps = 58/314 (18%)
Query: 1807 QSPLTPQP-----GNGNMSPAQSFHKELFTKQP-----PSTPTSTSSDDVFVKPQAPPPP 1856
QSPL P P G S + + QP PSTP S+S P + P
Sbjct: 812 QSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSA 871
Query: 1857 PAPSRIPIQDSLSQAQTSQPPS-----PQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVG 1911
P + +QAQ + P P V +P SS + P+P+ +A+ GTP
Sbjct: 872 TQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQ-PTPV--HAQPPGTP------ 922
Query: 1912 HSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDL---CSSSTTNNDPYAKPPD 1968
+AA ++N P S + N PV ++ + T DP +
Sbjct: 923 ----LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGE 978
Query: 1969 TPRPVMTDQFPKSLGLSRSPVVSEQTA-------KGP------------IAAGTSDHFTK 2009
+M + + + ++EQ + K P + GT+ T
Sbjct: 979 PRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTS 1038
Query: 2010 PS-PRADVFQRQRIPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSV-------S 2061
PS PR +F+ + + + L D PF+ P+ P Y + S
Sbjct: 1039 PSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLS 1098
Query: 2062 QASRRLSVDPYERP 2075
R+L Y+ P
Sbjct: 1099 TIKRKLDTGQYQEP 1112
Score = 44.7 bits (104), Expect = 0.002
Identities = 121/537 (22%), Positives = 186/537 (34%), Gaps = 75/537 (13%)
Query: 1529 SPANTQP----------TPLPQPPPPTQLLPIHNQDAFSRMPLMNGLIGSSPHLP----H 1574
S A TQP + +P PPPP Q P A + HL +
Sbjct: 1885 SVARTQPPTTVSTGKPTSQVPAPPPPAQPPPA----AVEAARQIEREAQQQQHLYRVNIN 1940
Query: 1575 NSLPPG-SGLGT-FSAIAQSSYPDARDKNSAFNPMASDPNNSWTSSAPTVEGENDTMSNA 1632
NS+PPG +G+GT S +A S R + M S P W AP + + M
Sbjct: 1941 NSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQW-QQAPLPQQQ--PMPGL 1997
Query: 1633 QRSTLKWEKEEALG--EMATVAPV----------LYTNINFPNLKEEFPDWTTRVKQIAK 1680
R + + + A+ M +V P L + P+ ++ +K +
Sbjct: 1998 PRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQ 2057
Query: 1681 LWRKASSQERAPYV--QKARDNRAALRINKVQMSNDSMKRQQQQDSID--------PSSR 1730
L Q A YV Q + L+ M +Q +++ P
Sbjct: 2058 LMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVP 2117
Query: 1731 IDSELFKDPLKQRESEHEQEWKFRQQMRQKSKQQAKIEATQKLEQVKNEQQQQQQQQFGS 1790
+ Q ++ + M + Q ++ Q L+Q + +QQQQQQQQ
Sbjct: 2118 PQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQ 2177
Query: 1791 QHLLVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQP--PSTPTSTSSDDVFV 1848
Q +G Q P G G PA + + P S+ ++ +
Sbjct: 2178 QGSAGMAGGMAGHGQFQQP----QGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQL 2233
Query: 1849 KPQAPPPPPAPSRIPIQDSLSQ-AQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMV-GTPR 1906
P A S IQ +L Q Q Q+ SPG P+PM P M+ G P+
Sbjct: 2234 GQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQ-----PNPMSPQQHMLSGQPQ 2288
Query: 1907 P-----PPVGHSFSRR-NSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNN 1960
+ S S + S APV++ P S+P + + +P P S T +
Sbjct: 2289 ASHLPGQQIATSLSNQVRSPAPVQSPRP---QSQPPHSSPSPRIQPQPSPHHVSPQTGSP 2345
Query: 1961 DP-----YAKPPD---TPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTK 2009
P A D P + P+ SRS + SE + G T + F +
Sbjct: 2346 HPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVE 2402
Score = 43.9 bits (102), Expect = 0.004
Identities = 101/516 (19%), Positives = 182/516 (35%), Gaps = 58/516 (11%)
Query: 3405 REQQERQRIQLMQEVDRQRALQQRMEMEQHGMVGSEISSSRTSVSQIPFYSSDLPCDFMQ 3464
R++ + + ++ ++ ++R + + G++G++ + +Q P P
Sbjct: 609 RDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPG-AQPPVIPQAQPV--RP 665
Query: 3465 PLGPLQQSPQHQQQMGQVLQQQN-IQQGSINSPST----QTFMQTNERRQVGPPSFVPDS 3519
P GPL P ++ Q+ Q + N + G++ P + N Q+ VP
Sbjct: 666 PNGPLSL-PVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGM 724
Query: 3520 PSIPVGSPNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAAPPVANSSLPCGQDSTITHG 3579
P P ++ H N Q+P + F P S+ GQ T
Sbjct: 725 AISPSRMPQPPNMMGAHTN---NMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQT-- 779
Query: 3580 HSYPGSTQSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTKAPSTPHSDITAPPTPGISE 3639
G +Q Q+ +P + + TP TA P +
Sbjct: 780 ----GVSQG--QVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQH 833
Query: 3640 TTSTPAVSTPSELPQQADQESVEPVGPSTPNMAAGQLCTELENKLPNSDFSQATPNQQTY 3699
TT P TP PQ A P PSTP ++GQ T +P++ +Q+TP Q
Sbjct: 834 TT--PPGMTP---PQPA-----APTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAA 883
Query: 3700 ANSEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVEGNAVACPVSSAQSP 3759
A ++V TP ++ T Q+ + Q A A + +P
Sbjct: 884 AQAQV------TPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTP 937
Query: 3760 PHSAGAPAAKGDSGNELLKHLLKNKKSSSLLNQKPE--------GSICSEDDCTKDNKLV 3811
A A G ++ +L+ K + + +P+ S E+D +++
Sbjct: 938 SSVASAETNSQQPGPDV--PVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVK 995
Query: 3812 EKQNPAEGLQTLGAQMQGGFGCGNQLPKTDGGSETKKQRSKRTQRTGEKAAPRSKKRK-- 3869
E+ + AE Q + P+ E K++ + T ++ S+ RK
Sbjct: 996 EETDIAE-------QKSEPMEVDEKKPEVK--VEVKEEEESSSNGTASQSTSPSQPRKKI 1046
Query: 3870 -KDEEEKQAMYSSTDTFTHLKQQNNLSNPPTPPASL 3904
K EE +QA+ + + ++ P P L
Sbjct: 1047 FKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLL 1082
Score = 40.0 bits (92), Expect = 0.057
Identities = 37/129 (28%), Positives = 53/129 (41%), Gaps = 26/129 (20%)
Query: 3234 LKHVTEQQSMVQKQLEQIRKQQKEHAEL----IEDYRIKQQQQCAMAPPTMMPSVQ--PQ 3287
+KH QQ +Q +L+Q + ++ A + + + PT PS PQ
Sbjct: 1808 IKHKLRQQQ-IQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQ 1866
Query: 3288 PPLIPGATPPTMSQPTFPMVPQQLQHQQHTTVISGHTSPVRMPSLPGWQPNSAPAHLPLN 3347
PP P +P +MS FP V + Q TTV +G +P S +P
Sbjct: 1867 PPAQPQPSPVSMSPAGFPSVART---QPPTTVSTG-------------KPTS---QVPAP 1907
Query: 3348 PPRIQPPIA 3356
PP QPP A
Sbjct: 1908 PPPAQPPPA 1916
Score = 38.5 bits (88), Expect = 0.17
Identities = 92/395 (23%), Positives = 133/395 (33%), Gaps = 54/395 (13%)
Query: 2375 QADTEKLRQRQKLREIILQQQQQKKIAGRQEKG-SQDSPAVPHPGPLQHWQPEN---VNQ 2430
Q + E+ R+ + ++ IL Q G Q Q P P GPL P N V+Q
Sbjct: 624 QKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLS--LPVNRMQVSQ 681
Query: 2431 AFTRPPPPYPGNIRSPVAPPLGPRYAV-----FPKDQRGPYPPDVASMGMRPH--GFRFG 2483
P GN++ P AP +GPR A + G P S P
Sbjct: 682 GMNSFNPMSLGNVQLPQAP-MGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGA 740
Query: 2484 FPGGSHGTMPSQERFLVPPQQIQGSGV------SPQLRRSVS------VDMPRPLNN--- 2528
P+Q +FL Q SG P + VS +P PLN
Sbjct: 741 HTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGP 800
Query: 2529 --SQMNNPVGLPQHFSPQSLPVQQHNILGQAYIELRHRAPDGRQRLPFSAPPGSVVEASS 2586
SQ+ P P P L+H P G P + + S+
Sbjct: 801 QASQLPCPPVTQSPLHPTPPPAST----AAGMPSLQHTTPPGMT----PPQPAAPTQPST 852
Query: 2587 NLRHGNFIPRPDFPG--PRHTDPMRRPP-------QGLPN-QLPVHPDLEQVPPSQQEQG 2636
+ P P PG P T P Q P Q PV P P S Q+Q
Sbjct: 853 PVSSSGQTPTPT-PGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQP 911
Query: 2637 HSVHSSSMVMRTLNHPLGGEFSEAPLSTSVPSETTSDNLQITTQPSDGLEEKLDSDDPSV 2696
VH+ L+ + P +SV S T+ P ++ + ++D
Sbjct: 912 TPVHAQP-PGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAED--- 967
Query: 2697 KELDVKDLEGVEVKDLDDEDLENLNLDTEDGKVVE 2731
E D + +G ++ +EDL+ + E+ + E
Sbjct: 968 TEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAE 1002
Score = 38.1 bits (87), Expect = 0.22
Identities = 42/188 (22%), Positives = 61/188 (32%), Gaps = 38/188 (20%)
Query: 3281 MPSVQPQPPLIPGATPPTMSQPTFPMVPQQLQHQQHTTVISGHTSPVRMPSLPGWQPNSA 3340
MPS+Q P PG TPP + PT P P Q T S + S P Q +
Sbjct: 828 MPSLQHTTP--PGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQ 885
Query: 3341 PAHLPLNPPRIQPPIAQLP-------------------------IKTCTPAPGTVSNANP 3375
P +QPP P I P P +V++A
Sbjct: 886 AQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAET 945
Query: 3376 QSGPP----------PRVEFDDNNPFSESFQERERKERLREQQERQRIQLMQEVDRQRAL 3425
S P + +D P + R E + E + Q+ +E D
Sbjct: 946 NSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGAS-QVKEETDIAEQK 1004
Query: 3426 QQRMEMEQ 3433
+ ME+++
Sbjct: 1005 SEPMEVDE 1012
Score = 35.0 bits (79), Expect = 1.8
Identities = 71/317 (22%), Positives = 110/317 (34%), Gaps = 78/317 (24%)
Query: 2177 QPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEG---F 2233
QP P P Q + P A P P +S+P + R ++S+G F
Sbjct: 644 QPALPAPGAQPPVI-----------PQAQPVRPPNGPLSLPVN------RMQVSQGMNSF 686
Query: 2234 TRSSMTRPVLMPNQDPFLQAAQ--------NRGPALPGPLVRPPDTCSQTPRPPGPGLSD 2285
S+ V +P +AA N ++PG + P S+ P+PP +
Sbjct: 687 NPMSLGN-VQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISP----SRMPQPPNMMGAH 741
Query: 2286 TFSRVSPSAARD---PYDQSPMTPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSNSPM 2342
T + ++ + A+ P +Q P + + S G V+ PG A+ +P+
Sbjct: 742 TNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPG------AALPNPL 795
Query: 2343 HSQGQQFSGVSQLP-GPVPTSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKKIA 2401
+ G Q SQLP PV S + T + A A
Sbjct: 796 NMLGPQ---ASQLPCPPVTQSPLHPTPPPASTA--------------------------A 826
Query: 2402 GRQEKGSQDSPAVPHPGPLQHWQPENVNQAFTRPPPPYPGNIRSPVAPPLGP------RY 2455
G P + P P QP + + P P PG++ S P +
Sbjct: 827 GMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQA 886
Query: 2456 AVFPKDQRGPYPPDVAS 2472
V P+ Q PP VA+
Sbjct: 887 QVTPQPQTPVQPPSVAT 903
Score = 33.5 bits (75), Expect = 5.3
Identities = 45/188 (23%), Positives = 67/188 (35%), Gaps = 32/188 (17%)
Query: 3890 QQNNLSNPPTPPASLPPTPPPMAC--------QKMANGFATTEELAGKAGVLVSHEVTKT 3941
Q + L PP + L PTPPP + G + A +T
Sbjct: 801 QASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQT 860
Query: 3942 LGPKPFQLPFRPQDD----LLARALAQ---GPKTVDVPASLPTPPHNNQEELRIQDHCGD 3994
P P +P Q + A A AQ P+T P S+ TP + Q+
Sbjct: 861 PTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQ---------- 910
Query: 3995 RDTPDSFVPSSSPESVVGVEV-SRYP-DLSLVKEEPPEPVPSPIIPILPSTAGKSSESRR 4052
TP P +P S + +R P S+ E P P +P+L +E++
Sbjct: 911 -PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLE----MKTETQA 965
Query: 4053 NDIKTEPG 4060
D + +PG
Sbjct: 966 EDTEPDPG 973
>gi|119943104 CREB binding protein isoform a [Homo sapiens]
Length = 2442
Score = 82.4 bits (202), Expect = 1e-14
Identities = 157/622 (25%), Positives = 224/622 (36%), Gaps = 125/622 (20%)
Query: 2112 PSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTV 2171
PS + PGT ++ S QPP P+P S S + + + T QPP T +T
Sbjct: 1883 PSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVART----QPPTT--VSTG 1936
Query: 2172 DPYSQQPQTPRPSTQTDLFVTPVTN-QRHSDPYAH----------PPGTPRPGISVPYSQ 2220
P SQ P P P+ V +R + H PPG R G+ P SQ
Sbjct: 1937 KPTSQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPG--RTGMGTPGSQ 1994
Query: 2221 PPA----TPRPRISEGFTRSSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTP 2276
PRP G SM P Q P Q Q P LP P++ +
Sbjct: 1995 MAPVSLNVPRPNQVSGPVMPSM--PPGQWQQAPLPQ--QQPMPGLPRPVI-SMQAQAAVA 2049
Query: 2277 RPPGPGLSDTFSRVSPSAARDPYD--QSPMTPRSQSD-------------SFGTSQTAHD 2321
P P + S +SPSA +D +SP +P+ Q +F +TA
Sbjct: 2050 GPRMPSVQPPRS-ISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKY 2108
Query: 2322 VAD----QPRPGSEGSFCASSNSPMHSQGQQFSGVSQLPGPVPTSGVTDTQNTVNMAQAD 2377
VA+ QP+PG + MH Q ++ + VP GV Q +
Sbjct: 2109 VANQPGMQPQPGLQSQPGMQPQPGMHQQ-PSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQ 2167
Query: 2378 TEKL----------------RQRQKLREIILQQQQQKKIAGRQEKGSQDSPAVPHPGPLQ 2421
+ L + R+ LR +LQQQQQ++ +Q++ Q A G
Sbjct: 2168 GQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAG 2227
Query: 2422 HWQPENVNQAFTRPPPPYPGNIRSPVAPPLGPRYAVFPKDQRGPYPPDV-ASMGMRPHGF 2480
H Q F +P P G YPP + M+ H
Sbjct: 2228 HGQ-------FQQPQGP-------------------------GGYPPAMQQQQRMQQH-- 2253
Query: 2481 RFGFPGGSHGTMPSQERFL-VPPQQIQGSGVSPQLRRSVSVDMPRPLNNSQMNNPVGLPQ 2539
G S G M +Q L Q G+ +P +++++ R L QM +G P
Sbjct: 2254 -LPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQQAL---QQRILQQQQMKQQIGSPG 2309
Query: 2540 HFSPQSLPVQQHNILGQ---AYIELRHRAPDGRQRLPFSAPPGSVVEASSNLRHGNFIPR 2596
+P S QQH + GQ +++ + A ++ AP S S H + PR
Sbjct: 2310 QPNPMS--PQQHMLSGQPQASHLPGQQIATSLSNQVRSPAPVQS-PRPQSQPPHSSPSPR 2366
Query: 2597 -PDFPGPRHTDPMRRPPQGLPNQLPVHPDLEQVPPSQQEQGHSVH-SSSMVMRTLNHPLG 2654
P P H P P HP L S +QGH + S ++ LN P
Sbjct: 2367 IQPQPSPHHVSPQTGSP---------HPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSR 2417
Query: 2655 GEFSEAPLSTSVPSETTSDNLQ 2676
S S+ +TT D L+
Sbjct: 2418 SALSS---ELSLVGDTTGDTLE 2436
Score = 58.2 bits (139), Expect = 2e-07
Identities = 89/331 (26%), Positives = 123/331 (37%), Gaps = 50/331 (15%)
Query: 3242 SMVQKQLEQIRKQQKEHAELIEDYRIKQQQQCAMAPPTMMPSVQPQPPLIPGATPPTMSQ 3301
SM Q +Q Q++ + I Q Q A+A P M PSVQP + P A +
Sbjct: 2015 SMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRM-PSVQPPRSISPSALQDLLRT 2073
Query: 3302 PTFPMVPQQLQH---------QQHTTVISGHTSPVRMPSLPGWQPN----SAPAHLPLNP 3348
P PQQ Q Q I T+ + + PG QP S P P
Sbjct: 2074 LKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKY-VANQPGMQPQPGLQSQPGMQPQPG 2132
Query: 3349 PRIQPPIAQL-PIKTCTPAPGT------VSNANPQSGPPPRVEFDDNNPFSESFQERERK 3401
QP + L ++ P PG + NPQ G + +NP S + R
Sbjct: 2133 MHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLNPQ-GQALNIMNPGHNPNMASMNPQYR- 2190
Query: 3402 ERLREQQERQRIQLMQEVDRQRALQQRMEMEQHGMVGSEISSSRTSVSQIPFYSSDLPCD 3461
E R QL+Q+ +Q+ QQ+ + +Q G G ++ Q
Sbjct: 2191 -------EMLRRQLLQQQQQQQQQQQQQQQQQQGSAG--MAGGMAGHGQ----------- 2230
Query: 3462 FMQPLGPLQQSPQHQQQMGQVLQQQNIQQGSINSPSTQTFMQTNERRQVGPPSFVPDS-P 3520
F QP GP P QQQ Q +QQ QG S Q Q + Q+G P DS P
Sbjct: 2231 FQQPQGPGGYPPAMQQQ--QRMQQHLPLQG---SSMGQMAAQMGQLGQMGQPGLGADSTP 2285
Query: 3521 SIPVGSPNFSSVKQGHGNLSGTSFQQSPVRP 3551
+I +Q G+ Q +P+ P
Sbjct: 2286 NIQQALQQRILQQQQMKQQIGSPGQPNPMSP 2316
Score = 55.8 bits (133), Expect = 1e-06
Identities = 94/408 (23%), Positives = 140/408 (34%), Gaps = 87/408 (21%)
Query: 3365 PAPGTVSNANPQSGP--PPRVEFDDNNPFSESFQERERKERLREQQERQ--RIQLMQEVD 3420
PAPG PQ+ P PP N P S + + + +QL Q
Sbjct: 686 PAPGAQPPVIPQAQPVRPP------NGPLSLPVNRMQVSQGMNSFNPMSLGNVQLPQAPM 739
Query: 3421 RQRA---LQQRMEMEQHGMV-GSEISSSR-------------TSVSQIPFYSSDLPCD-F 3462
RA + ++M G V G IS SR ++Q P S LP + F
Sbjct: 740 GPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNNMMAQAPAQSQFLPQNQF 799
Query: 3463 MQPLGPLQQSPQHQQQMGQVLQQQNIQQGSINSPSTQTFMQTNERRQVGPPSFVPDSPSI 3522
G + MGQ Q + QG + + N +GP + P
Sbjct: 800 PSSSGAMSVG------MGQPPAQTGVSQGQVPGAALP-----NPLNMLGPQA--SQLPCP 846
Query: 3523 PVGSPNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAAP-----PVANSSLPCGQDSTIT 3577
PV +G Q P TP PAAP PV++S GQ T T
Sbjct: 847 PVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSS----GQTPTPT 902
Query: 3578 HGHSYPGSTQSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTKAPSTPHSDITAPPTPGI 3637
G S P +TQ+ + T + A+ T P TP
Sbjct: 903 PG-SVPSATQT----------------QSTPTVQAAAQAQVTPQPQTP------------ 933
Query: 3638 SETTSTPAVSTPSELPQQADQESVEPVGPSTPNMAAGQLCTELENKLPNSDFSQATPNQQ 3697
P+V+TP Q+ Q+ PV P Q ++N++P +
Sbjct: 934 ---VQPPSVATP-----QSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNS 985
Query: 3698 TYANSEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVE 3745
+V L M+T + E+ + + E++ P E + + Q S+V+
Sbjct: 986 QQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVK 1033
Score = 54.7 bits (130), Expect = 2e-06
Identities = 130/579 (22%), Positives = 208/579 (35%), Gaps = 161/579 (27%)
Query: 2892 NVIQASTQLPAQDVINSCGITGSTPVLSSLLANEKSDNSDIRPSGSP------PPPTLPA 2945
NV Q S P + STP A + + P+G P PP T+
Sbjct: 1876 NVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVST 1935
Query: 2946 S-PSNHVSSLPPFIAPPGRVLDNAMNSNVTVVSRVNHVFSQGVQVNPGLIPGQSTVNHSL 3004
P++ V + PP PP ++ A + H++ V +N + PG++
Sbjct: 1936 GKPTSQVPAPPPPAQPPPAAVEAARQIE-REAQQQQHLYR--VNINNSMPPGRT------ 1986
Query: 3005 GTGKPATQTGPQT-SQSGTSSMSGP----------QQLMIPQTLAQQNRERPLLLEE--- 3050
G G P +Q P + + + +SGP QQ +PQ RP++ +
Sbjct: 1987 GMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQA 2046
Query: 3051 ----------------QPLLLQDLL----DQERQEQQQQ---------RQMQAMIRQRSE 3081
P LQDLL +QQQQ + M A I+QR+
Sbjct: 2047 AVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTA 2106
Query: 3082 PFFPNIDFDAITDPIMKAK--MVALKGINKVMAQNNL----------GMPPMVMSRFPFM 3129
+ N P ++++ M G+++ + NL G+PP
Sbjct: 2107 KYVAN-QPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQ-------- 2157
Query: 3130 GQVVTGTQNSEGQNLGPQAIPQDGSITHQISRPNPPNFGPGFVNDSQRKQYEEWLQETQQ 3189
Q G N +GQ L +I + PN + P + + R+Q LQ+ QQ
Sbjct: 2158 -QQAMGGLNPQGQAL---------NIMNPGHNPNMASMNPQY-REMLRRQL---LQQQQQ 2203
Query: 3190 LLQMQQKYLEEQIGAHRKSKKALSAKQRTAKKAGREFP---EEDAEQLKHVTEQQSMVQK 3246
Q QQ+ ++Q G+ + Q + +P ++ +H+ Q S + +
Sbjct: 2204 QQQQQQQQQQQQQGSAGMAGGMAGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQ 2263
Query: 3247 QLEQIRK-----------------QQKEHAELIEDYRIKQQ-----QQCAMAPPTMMPSV 3284
Q+ + QQ +++ ++KQQ Q M+P M S
Sbjct: 2264 MAAQMGQLGQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSG 2323
Query: 3285 QPQPPLIPGATPPTMSQPTFPMVPQQLQHQQHTTVISGHT---SPVRMPSLPGWQPNSAP 3341
QPQ +PG QQ T +S +PV+ P P+S+P
Sbjct: 2324 QPQASHLPG--------------------QQIATSLSNQVRSPAPVQSPRPQSQPPHSSP 2363
Query: 3342 AHLPLNPPRIQPPIAQLPIKTCTPAPGTVSNANPQSGPP 3380
+ PRIQP P+P VS PQ+G P
Sbjct: 2364 S------PRIQP----------QPSPHHVS---PQTGSP 2383
Score = 53.9 bits (128), Expect = 4e-06
Identities = 114/486 (23%), Positives = 166/486 (34%), Gaps = 68/486 (13%)
Query: 1770 TQKLEQVKNEQ--QQQQQQQFGSQHLLVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHK 1827
TQ QV +Q Q Q QQ + + L + + P+ GI + P N+ +
Sbjct: 498 TQLQPQVPGQQPAQPQTHQQMRTLNPLGNNPMNIPAGGITTDQQPP----NLISESALPT 553
Query: 1828 ELFTKQPPSTPTSTSSD--DVFVKPQAPPPPPAPSRIPIQDSLSQAQTSQP--------- 1876
L P S S + + P A PP R + ++Q S
Sbjct: 554 SLGATNPLMNDGSNSGNIGTLSTIPTAAPPSSTGVRKGWHEHVTQDLRSHLVHKLVQAIF 613
Query: 1877 PSPQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPL 1936
P+P P + R + YAK V G + NS +
Sbjct: 614 PTPD---PAALKDRRMENLVAYAKKVE-------GDMYESANSRDEYYHLLAEKIYKIQK 663
Query: 1937 QMNETTANRPSPVRDLCSSSTTNNDPYAKPPDTPR--PVMTDQFPKSLGLSRSPVVSEQT 1994
++ E +R + + + P A+PP P+ PV P SL ++R V
Sbjct: 664 ELEEKRRSRLHK-QGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRMQVSQGMN 722
Query: 1995 AKGPIAAGTSDHFTKP-SPRA--------DVFQRQRIPDSYARPLLTPAPLDS-GPGPFK 2044
+ P++ G P PRA + +P P P P + G
Sbjct: 723 SFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGAHTNN 782
Query: 2045 TPMQPPPSSQD-PYGSVSQASRRLSVDPYERPALT------------PRPIDNFSHNQSN 2091
Q P SQ P +S +SV + PA T P P++ S
Sbjct: 783 MMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGPQASQ 842
Query: 2092 ---DPYSQPPLTPHPAVNESFAH-PSRAFSQPGTISRPTSQDPYSQPPGTPRPVVDSYSQ 2147
P +Q PL P P + A PS + P P P P P V S Q
Sbjct: 843 LPCPPVTQSPLHPTPPPASTAAGMPSLQHTTP-----PGMTPPQPAAPTQPSTPVSSSGQ 897
Query: 2148 SSGTARSNTDPYSQPPGTPRPTTVDPYSQQPQTPRPST--QTDLFVTPVTNQRHSDP-YA 2204
+ + +Q TP TV +Q TP+P T Q TP ++Q+ P +A
Sbjct: 898 TPTPTPGSVPSATQTQSTP---TVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHA 954
Query: 2205 HPPGTP 2210
PPGTP
Sbjct: 955 QPPGTP 960
Score = 50.1 bits (118), Expect = 6e-05
Identities = 94/420 (22%), Positives = 146/420 (34%), Gaps = 79/420 (18%)
Query: 1826 HKELFTKQPPSTPTSTSSDDVFVKPQAPPPPPAPSRIPIQDSLSQAQTSQPPSPQVFSPG 1885
HK+ P+ P + V + Q PP P +P+ ++ Q SQ F+P
Sbjct: 674 HKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPV----NRMQVSQ--GMNSFNPM 727
Query: 1886 SSNS--RPPSPMDPYAKMVGTPRPPPVGHSFSRRNSAAPVENCTPLSSVSRPLQMNETTA 1943
S + P +PM P A A+P+ + ++S+ M + +
Sbjct: 728 SLGNVQLPQAPMGPRA--------------------ASPMNHSVQMNSMGSVPGMAISPS 767
Query: 1944 NRPSPVRDLCSSSTTNNDPYAKPPDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGT 2003
P P + N+ A+ P + + +QFP S G + S + + A+ ++ G
Sbjct: 768 RMPQPPNMM---GAHTNNMMAQAPAQSQFLPQNQFPSSSG-AMSVGMGQPPAQTGVSQGQ 823
Query: 2004 SDHFTKPSPRADVF-QRQRIPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSVSQ 2062
P+P + Q ++P P +T +PL P P T P
Sbjct: 824 VPGAALPNPLNMLGPQASQLP----CPPVTQSPLHPTPPPASTAAGMP------------ 867
Query: 2063 ASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFSQPGTI 2122
S+ P +TP + Q + P S TP P P S T
Sbjct: 868 -----SLQHTTPPGMTPP--QPAAPTQPSTPVSSSGQTPTPT-------PGSVPSATQTQ 913
Query: 2123 SRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSN----TDPYSQPPGTPRPTTVDPYSQQP 2178
S PT Q +Q TP+P S T +S+ T ++QPPGTP +
Sbjct: 914 STPTVQ-AAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRV 972
Query: 2179 QTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFTRSSM 2238
TP + TN + P P + P P S+G RS M
Sbjct: 973 PTPSSVASAE------TNSQQPG-----PDVPVLEMKTETQAEDTEPDPGESKGEPRSEM 1021
Score = 50.1 bits (118), Expect = 6e-05
Identities = 124/611 (20%), Positives = 195/611 (31%), Gaps = 83/611 (13%)
Query: 1780 QQQQQQQQFGSQHLLVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQPPSTPT 1839
Q + QQ Q + + + + P + SP T PP TPT
Sbjct: 1856 QHRLQQAQLMRRRMATMNTRNVPQQSLPSP---------------------TSAPPGTPT 1894
Query: 1840 STSSDDVFVKPQAPPPPPAPSRIPIQDS----LSQAQTSQPPSPQVFSPGSSNSRPPSPM 1895
S PQ P PP P P+ S S A+T P + P S PP P
Sbjct: 1895 QQPS-----TPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQVPAPPPPA 1949
Query: 1896 DPYAKMVGTPRPPPVGHSFSRRNSAAPVENCTP--------LSSVSRPLQMNETTANRPS 1947
P V R + + N P S P+ +N N+ S
Sbjct: 1950 QPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVS 2009
Query: 1948 -PVRDLCSSSTTNNDPYAKP---PDTPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGT 2003
PV P + P PRPV++ Q ++ R P V + P A
Sbjct: 2010 GPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSVQPPRSISPSALQD 2069
Query: 2004 SDHFTKPSPRADVFQRQRIPDSYARPLLTPAPLDSGPGPF---KTPMQPPPSSQDPYGSV 2060
T SP + Q+Q + + P L A + + + MQP P Q G
Sbjct: 2070 LLR-TLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQ 2128
Query: 2061 SQASRRLSVDPYERPALTPRPIDNFSHNQSNDPYSQPPLTPHPAVNESFAHPSRAFS--Q 2118
Q +++P+L N + Q+ P +P + P +A +
Sbjct: 2129 PQPGM------HQQPSL-----QNLNAMQAGVP--RPGVPPQQQAMGGLNPQGQALNIMN 2175
Query: 2119 PGTISRPTSQDPYSQPPGTPRPVVDSYSQSSGTARSNTDPYSQPPGTPRPTTVDPYSQQP 2178
PG S +P + R ++ Q + G QQP
Sbjct: 2176 PGHNPNMASMNPQYREM-LRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGMAGHGQFQQP 2234
Query: 2179 QTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEGFT---R 2235
Q P + + Q+ + G+ ++ Q +P + T +
Sbjct: 2235 QGPGG------YPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLGADSTPNIQ 2288
Query: 2236 SSMTRPVLMPNQDPFLQAAQNRGPALPGPLVRPPDTCSQTPRP---PGPGLSDTFSRV-- 2290
++ + +L Q Q P P P+ S P+ PG ++ + S
Sbjct: 2289 QALQQRILQQQQ----MKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQVR 2344
Query: 2291 SPSAARDPYDQSPMTPRSQSDSFGTSQTAHDVADQ---PRPGSEGSFCASSNSPMHSQGQ 2347
SP+ + P QS S S + H V+ Q P PG + +S + +
Sbjct: 2345 SPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQGHLGNPE 2404
Query: 2348 QFSGVSQLPGP 2358
Q + + QL P
Sbjct: 2405 QSAMLPQLNTP 2415
Score = 45.1 bits (105), Expect = 0.002
Identities = 70/314 (22%), Positives = 110/314 (35%), Gaps = 58/314 (18%)
Query: 1807 QSPLTPQP-----GNGNMSPAQSFHKELFTKQP-----PSTPTSTSSDDVFVKPQAPPPP 1856
QSPL P P G S + + QP PSTP S+S P + P
Sbjct: 850 QSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSA 909
Query: 1857 PAPSRIPIQDSLSQAQTSQPPS-----PQVFSPGSSNSRPPSPMDPYAKMVGTPRPPPVG 1911
P + +QAQ + P P V +P SS + P+P+ +A+ GTP
Sbjct: 910 TQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQ-PTPV--HAQPPGTP------ 960
Query: 1912 HSFSRRNSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDL---CSSSTTNNDPYAKPPD 1968
+AA ++N P S + N PV ++ + T DP +
Sbjct: 961 ----LSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAEDTEPDPGESKGE 1016
Query: 1969 TPRPVMTDQFPKSLGLSRSPVVSEQTA-------KGP------------IAAGTSDHFTK 2009
+M + + + ++EQ + K P + GT+ T
Sbjct: 1017 PRSEMMEEDLQGASQVKEETDIAEQKSEPMEVDEKKPEVKVEVKEEEESSSNGTASQSTS 1076
Query: 2010 PS-PRADVFQRQRIPDSYARPLLTPAPLDSGPGPFKTPMQPPPSSQDPYGSV-------S 2061
PS PR +F+ + + + L D PF+ P+ P Y + S
Sbjct: 1077 PSQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLS 1136
Query: 2062 QASRRLSVDPYERP 2075
R+L Y+ P
Sbjct: 1137 TIKRKLDTGQYQEP 1150
Score = 44.7 bits (104), Expect = 0.002
Identities = 121/537 (22%), Positives = 186/537 (34%), Gaps = 75/537 (13%)
Query: 1529 SPANTQP----------TPLPQPPPPTQLLPIHNQDAFSRMPLMNGLIGSSPHLP----H 1574
S A TQP + +P PPPP Q P A + HL +
Sbjct: 1923 SVARTQPPTTVSTGKPTSQVPAPPPPAQPPPA----AVEAARQIEREAQQQQHLYRVNIN 1978
Query: 1575 NSLPPG-SGLGT-FSAIAQSSYPDARDKNSAFNPMASDPNNSWTSSAPTVEGENDTMSNA 1632
NS+PPG +G+GT S +A S R + M S P W AP + + M
Sbjct: 1979 NSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQW-QQAPLPQQQ--PMPGL 2035
Query: 1633 QRSTLKWEKEEALG--EMATVAPV----------LYTNINFPNLKEEFPDWTTRVKQIAK 1680
R + + + A+ M +V P L + P+ ++ +K +
Sbjct: 2036 PRPVISMQAQAAVAGPRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQ 2095
Query: 1681 LWRKASSQERAPYV--QKARDNRAALRINKVQMSNDSMKRQQQQDSID--------PSSR 1730
L Q A YV Q + L+ M +Q +++ P
Sbjct: 2096 LMAAFIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVP 2155
Query: 1731 IDSELFKDPLKQRESEHEQEWKFRQQMRQKSKQQAKIEATQKLEQVKNEQQQQQQQQFGS 1790
+ Q ++ + M + Q ++ Q L+Q + +QQQQQQQQ
Sbjct: 2156 PQQQAMGGLNPQGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQ 2215
Query: 1791 QHLLVQSGSDTPSSGIQSPLTPQPGNGNMSPAQSFHKELFTKQP--PSTPTSTSSDDVFV 1848
Q +G Q P G G PA + + P S+ ++ +
Sbjct: 2216 QGSAGMAGGMAGHGQFQQP----QGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQL 2271
Query: 1849 KPQAPPPPPAPSRIPIQDSLSQ-AQTSQPPSPQVFSPGSSNSRPPSPMDPYAKMV-GTPR 1906
P A S IQ +L Q Q Q+ SPG P+PM P M+ G P+
Sbjct: 2272 GQMGQPGLGADSTPNIQQALQQRILQQQQMKQQIGSPGQ-----PNPMSPQQHMLSGQPQ 2326
Query: 1907 P-----PPVGHSFSRR-NSAAPVENCTPLSSVSRPLQMNETTANRPSPVRDLCSSSTTNN 1960
+ S S + S APV++ P S+P + + +P P S T +
Sbjct: 2327 ASHLPGQQIATSLSNQVRSPAPVQSPRP---QSQPPHSSPSPRIQPQPSPHHVSPQTGSP 2383
Query: 1961 DP-----YAKPPD---TPRPVMTDQFPKSLGLSRSPVVSEQTAKGPIAAGTSDHFTK 2009
P A D P + P+ SRS + SE + G T + F +
Sbjct: 2384 HPGLAVTMASSIDQGHLGNPEQSAMLPQLNTPSRSALSSELSLVGDTTGDTLEKFVE 2440
Score = 43.9 bits (102), Expect = 0.004
Identities = 101/516 (19%), Positives = 182/516 (35%), Gaps = 58/516 (11%)
Query: 3405 REQQERQRIQLMQEVDRQRALQQRMEMEQHGMVGSEISSSRTSVSQIPFYSSDLPCDFMQ 3464
R++ + + ++ ++ ++R + + G++G++ + +Q P P
Sbjct: 647 RDEYYHLLAEKIYKIQKELEEKRRSRLHKQGILGNQPALPAPG-AQPPVIPQAQPV--RP 703
Query: 3465 PLGPLQQSPQHQQQMGQVLQQQN-IQQGSINSPST----QTFMQTNERRQVGPPSFVPDS 3519
P GPL P ++ Q+ Q + N + G++ P + N Q+ VP
Sbjct: 704 PNGPLSL-PVNRMQVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGM 762
Query: 3520 PSIPVGSPNFSSVKQGHGNLSGTSFQQSPVRPSFTPALPAAPPVANSSLPCGQDSTITHG 3579
P P ++ H N Q+P + F P S+ GQ T
Sbjct: 763 AISPSRMPQPPNMMGAHTN---NMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQT-- 817
Query: 3580 HSYPGSTQSLIQLYSDIIPEEKGKKKRTRKKKRDDDAESTKAPSTPHSDITAPPTPGISE 3639
G +Q Q+ +P + + TP TA P +
Sbjct: 818 ----GVSQG--QVPGAALPNPLNMLGPQASQLPCPPVTQSPLHPTPPPASTAAGMPSLQH 871
Query: 3640 TTSTPAVSTPSELPQQADQESVEPVGPSTPNMAAGQLCTELENKLPNSDFSQATPNQQTY 3699
TT P TP PQ A P PSTP ++GQ T +P++ +Q+TP Q
Sbjct: 872 TT--PPGMTP---PQPA-----APTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAA 921
Query: 3700 ANSEVDKLSMETPAKTEEIKLEKAETESCPGQEEPKLEEQNGSKVEGNAVACPVSSAQSP 3759
A ++V TP ++ T Q+ + Q A A + +P
Sbjct: 922 AQAQV------TPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTP 975
Query: 3760 PHSAGAPAAKGDSGNELLKHLLKNKKSSSLLNQKPE--------GSICSEDDCTKDNKLV 3811
A A G ++ +L+ K + + +P+ S E+D +++
Sbjct: 976 SSVASAETNSQQPGPDV--PVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGASQVK 1033
Query: 3812 EKQNPAEGLQTLGAQMQGGFGCGNQLPKTDGGSETKKQRSKRTQRTGEKAAPRSKKRK-- 3869
E+ + AE Q + P+ E K++ + T ++ S+ RK
Sbjct: 1034 EETDIAE-------QKSEPMEVDEKKPEVK--VEVKEEEESSSNGTASQSTSPSQPRKKI 1084
Query: 3870 -KDEEEKQAMYSSTDTFTHLKQQNNLSNPPTPPASL 3904
K EE +QA+ + + ++ P P L
Sbjct: 1085 FKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLL 1120
Score = 40.0 bits (92), Expect = 0.057
Identities = 37/129 (28%), Positives = 53/129 (41%), Gaps = 26/129 (20%)
Query: 3234 LKHVTEQQSMVQKQLEQIRKQQKEHAEL----IEDYRIKQQQQCAMAPPTMMPSVQ--PQ 3287
+KH QQ +Q +L+Q + ++ A + + + PT PS PQ
Sbjct: 1846 IKHKLRQQQ-IQHRLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQ 1904
Query: 3288 PPLIPGATPPTMSQPTFPMVPQQLQHQQHTTVISGHTSPVRMPSLPGWQPNSAPAHLPLN 3347
PP P +P +MS FP V + Q TTV +G +P S +P
Sbjct: 1905 PPAQPQPSPVSMSPAGFPSVART---QPPTTVSTG-------------KPTS---QVPAP 1945
Query: 3348 PPRIQPPIA 3356
PP QPP A
Sbjct: 1946 PPPAQPPPA 1954
Score = 38.5 bits (88), Expect = 0.17
Identities = 92/395 (23%), Positives = 133/395 (33%), Gaps = 54/395 (13%)
Query: 2375 QADTEKLRQRQKLREIILQQQQQKKIAGRQEKG-SQDSPAVPHPGPLQHWQPEN---VNQ 2430
Q + E+ R+ + ++ IL Q G Q Q P P GPL P N V+Q
Sbjct: 662 QKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLS--LPVNRMQVSQ 719
Query: 2431 AFTRPPPPYPGNIRSPVAPPLGPRYAV-----FPKDQRGPYPPDVASMGMRPH--GFRFG 2483
P GN++ P AP +GPR A + G P S P
Sbjct: 720 GMNSFNPMSLGNVQLPQAP-MGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNMMGA 778
Query: 2484 FPGGSHGTMPSQERFLVPPQQIQGSGV------SPQLRRSVS------VDMPRPLNN--- 2528
P+Q +FL Q SG P + VS +P PLN
Sbjct: 779 HTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNMLGP 838
Query: 2529 --SQMNNPVGLPQHFSPQSLPVQQHNILGQAYIELRHRAPDGRQRLPFSAPPGSVVEASS 2586
SQ+ P P P L+H P G P + + S+
Sbjct: 839 QASQLPCPPVTQSPLHPTPPPAST----AAGMPSLQHTTPPGMT----PPQPAAPTQPST 890
Query: 2587 NLRHGNFIPRPDFPG--PRHTDPMRRPP-------QGLPN-QLPVHPDLEQVPPSQQEQG 2636
+ P P PG P T P Q P Q PV P P S Q+Q
Sbjct: 891 PVSSSGQTPTPT-PGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQP 949
Query: 2637 HSVHSSSMVMRTLNHPLGGEFSEAPLSTSVPSETTSDNLQITTQPSDGLEEKLDSDDPSV 2696
VH+ L+ + P +SV S T+ P ++ + ++D
Sbjct: 950 TPVHAQP-PGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLEMKTETQAED--- 1005
Query: 2697 KELDVKDLEGVEVKDLDDEDLENLNLDTEDGKVVE 2731
E D + +G ++ +EDL+ + E+ + E
Sbjct: 1006 TEPDPGESKGEPRSEMMEEDLQGASQVKEETDIAE 1040
Score = 38.1 bits (87), Expect = 0.22
Identities = 42/188 (22%), Positives = 61/188 (32%), Gaps = 38/188 (20%)
Query: 3281 MPSVQPQPPLIPGATPPTMSQPTFPMVPQQLQHQQHTTVISGHTSPVRMPSLPGWQPNSA 3340
MPS+Q P PG TPP + PT P P Q T S + S P Q +
Sbjct: 866 MPSLQHTTP--PGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQ 923
Query: 3341 PAHLPLNPPRIQPPIAQLP-------------------------IKTCTPAPGTVSNANP 3375
P +QPP P I P P +V++A
Sbjct: 924 AQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAET 983
Query: 3376 QSGPP----------PRVEFDDNNPFSESFQERERKERLREQQERQRIQLMQEVDRQRAL 3425
S P + +D P + R E + E + Q+ +E D
Sbjct: 984 NSQQPGPDVPVLEMKTETQAEDTEPDPGESKGEPRSEMMEEDLQGAS-QVKEETDIAEQK 1042
Query: 3426 QQRMEMEQ 3433
+ ME+++
Sbjct: 1043 SEPMEVDE 1050
Score = 35.0 bits (79), Expect = 1.8
Identities = 71/317 (22%), Positives = 110/317 (34%), Gaps = 78/317 (24%)
Query: 2177 QPQTPRPSTQTDLFVTPVTNQRHSDPYAHPPGTPRPGISVPYSQPPATPRPRISEG---F 2233
QP P P Q + P A P P +S+P + R ++S+G F
Sbjct: 682 QPALPAPGAQPPVI-----------PQAQPVRPPNGPLSLPVN------RMQVSQGMNSF 724
Query: 2234 TRSSMTRPVLMPNQDPFLQAAQ--------NRGPALPGPLVRPPDTCSQTPRPPGPGLSD 2285
S+ V +P +AA N ++PG + P S+ P+PP +
Sbjct: 725 NPMSLGN-VQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISP----SRMPQPPNMMGAH 779
Query: 2286 TFSRVSPSAARD---PYDQSPMTPRSQSDSFGTSQTAHDVADQPRPGSEGSFCASSNSPM 2342
T + ++ + A+ P +Q P + + S G V+ PG A+ +P+
Sbjct: 780 TNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPG------AALPNPL 833
Query: 2343 HSQGQQFSGVSQLP-GPVPTSGVTDTQNTVNMAQADTEKLRQRQKLREIILQQQQQKKIA 2401
+ G Q SQLP PV S + T + A A
Sbjct: 834 NMLGPQ---ASQLPCPPVTQSPLHPTPPPASTA--------------------------A 864
Query: 2402 GRQEKGSQDSPAVPHPGPLQHWQPENVNQAFTRPPPPYPGNIRSPVAPPLGP------RY 2455
G P + P P QP + + P P PG++ S P +
Sbjct: 865 GMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTVQAAAQA 924
Query: 2456 AVFPKDQRGPYPPDVAS 2472
V P+ Q PP VA+
Sbjct: 925 QVTPQPQTPVQPPSVAT 941
Score = 33.5 bits (75), Expect = 5.3
Identities = 45/188 (23%), Positives = 67/188 (35%), Gaps = 32/188 (17%)
Query: 3890 QQNNLSNPPTPPASLPPTPPPMAC--------QKMANGFATTEELAGKAGVLVSHEVTKT 3941
Q + L PP + L PTPPP + G + A +T
Sbjct: 839 QASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQT 898
Query: 3942 LGPKPFQLPFRPQDD----LLARALAQ---GPKTVDVPASLPTPPHNNQEELRIQDHCGD 3994
P P +P Q + A A AQ P+T P S+ TP + Q+
Sbjct: 899 PTPTPGSVPSATQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQ---------- 948
Query: 3995 RDTPDSFVPSSSPESVVGVEV-SRYP-DLSLVKEEPPEPVPSPIIPILPSTAGKSSESRR 4052
TP P +P S + +R P S+ E P P +P+L +E++
Sbjct: 949 -PTPVHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVPVLE----MKTETQA 1003
Query: 4053 NDIKTEPG 4060
D + +PG
Sbjct: 1004 EDTEPDPG 1011
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.130 0.388
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 234,335,462
Number of Sequences: 37866
Number of extensions: 13983553
Number of successful extensions: 121651
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 353
Number of HSP's successfully gapped in prelim test: 1982
Number of HSP's that attempted gapping in prelim test: 64294
Number of HSP's gapped (non-prelim): 47473
length of query: 4911
length of database: 18,247,518
effective HSP length: 124
effective length of query: 4787
effective length of database: 13,552,134
effective search space: 64874065458
effective search space used: 64874065458
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 73 (32.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.