Guide to the Human Genome
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Name: SETD2 Sequence: fasta or formatted (2564aa) NCBI GI: 197313748
Description:

SET domain containing 2

Referenced in:

Additional Brain Proteins
Histones, Related Proteins, and Modifying Enzymes
WW Domain

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.3        109           3
 C cysteine            2.1         53           2
 D aspartate           6.5        167           2
 E glutamate           8.9        229           5
 F phenylalanine       2.4         61           2
 G glycine             4.7        120           2
 H histidine           2.3         59           2
 I isoleucine          3.4         87           3
 K lysine              8.1        208           3
 L leucine             7.0        180           2
 M methionine          1.6         41           1
 N asparagine          3.9         99           2
 P proline             7.5        192           7
 Q glutamine           5.0        127           4
 R arginine            5.5        140           3
 S serine             12.3        315           3
 T threonine           6.0        155           3
 V valine              5.1        131           4
 W tryptophan          0.7         17           1
 Y tyrosine            2.9         74           3
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   SET domain containing 2 
WHSC1                 0.034   Wolf-Hirschhorn syndrome candidate 1 protein isoform...
WHSC1                 0.034   Wolf-Hirschhorn syndrome candidate 1 protein isoform...
WHSC1                 0.034   Wolf-Hirschhorn syndrome candidate 1 protein isoform...
WHSC1                 0.034   Wolf-Hirschhorn syndrome candidate 1 protein isofor...
WHSC1L1               0.033   WHSC1L1 protein isoform long 
NSD1                  0.031   nuclear receptor binding SET domain protein 1 isofor...
NSD1                  0.031   nuclear receptor binding SET domain protein 1 isofor...
ASH1L                 0.029   absent, small, or homeotic 1-like 
SUV39H2               0.015   suppressor of variegation 3-9 homolog 2 
EHMT1                 0.015   euchromatic histone-lysine N-methyltransferase 1 is...
SETMAR                0.015   SET domain and mariner transposase fusion 
SUV39H1               0.014   suppressor of variegation 3-9 homolog 1 
MLL2                  0.014   myeloid/lymphoid or mixed-lineage leukemia 2 
EZH2                  0.014   enhancer of zeste 2 isoform b 
EZH2                  0.014   enhancer of zeste 2 isoform a 
EZH1                  0.014   enhancer of zeste homolog 1 
MLL                   0.013   myeloid/lymphoid or mixed-lineage leukemia protein [...
EHMT2                 0.013   euchromatic histone-lysine N-methyltransferase 2 is...
EHMT2                 0.013   euchromatic histone-lysine N-methyltransferase 2 is...
MLL3                  0.012   myeloid/lymphoid or mixed-lineage leukemia 3 
SETD1B                0.012   SET domain containing 1B 
DSPP                  0.012   dentin sialophosphoprotein preproprotein 
SETD1A                0.012   SET domain containing 1A 
MLL4                  0.012   myeloid/lymphoid or mixed-lineage leukemia 4 
SFRS18                0.009   splicing factor, arginine/serine-rich 130 
SFRS18                0.009   splicing factor, arginine/serine-rich 130 
LOC100170229          0.009   hypothetical protein LOC100170229 
KIF20B                0.009   M-phase phosphoprotein 1 
NEFM                  0.008   neurofilament, medium polypeptide 150kDa isoform 1 ...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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