Guide to the Human Genome
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Name: EZH2 Sequence: fasta or formatted (707aa) NCBI GI: 23510384
Description:

enhancer of zeste 2 isoform b

Referenced in:

Histones, Related Proteins, and Modifying Enzymes
Stem Cells and Early Development

Other entries for this name:
alt prot [751aa] enhancer of zeste 2 isoform a
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.5         39           3
 C cysteine            4.7         33           1
 D aspartate           7.2         51           7
 E glutamate           8.8         62           4
 F phenylalanine       4.1         29           2
 G glycine             5.4         38           2
 H histidine           2.4         17           1
 I isoleucine          5.0         35           2
 K lysine              8.3         59           3
 L leucine             5.4         38           3
 M methionine          1.6         11           2
 N asparagine          5.2         37           2
 P proline             5.9         42           2
 Q glutamine           4.2         30           2
 R arginine            7.4         52           3
 S serine              6.4         45           4
 T threonine           4.4         31           1
 V valine              4.4         31           2
 W tryptophan          0.8          6           1
 Y tyrosine            3.0         21           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   enhancer of zeste 2 isoform b 
EZH2                  0.980   enhancer of zeste 2 isoform a 
EZH1                  0.621   enhancer of zeste homolog 1 
SETD1B                0.053   SET domain containing 1B 
MLL                   0.051   myeloid/lymphoid or mixed-lineage leukemia protein [...
ASH1L                 0.051   absent, small, or homeotic 1-like 
SUV39H1               0.050   suppressor of variegation 3-9 homolog 1 
SETD2                 0.050   SET domain containing 2 
NSD1                  0.050   nuclear receptor binding SET domain protein 1 isofor...
NSD1                  0.050   nuclear receptor binding SET domain protein 1 isofor...
SETD1A                0.049   SET domain containing 1A 
WHSC1                 0.048   Wolf-Hirschhorn syndrome candidate 1 protein isoform...
WHSC1                 0.048   Wolf-Hirschhorn syndrome candidate 1 protein isoform...
WHSC1                 0.048   Wolf-Hirschhorn syndrome candidate 1 protein isoform...
WHSC1                 0.048   Wolf-Hirschhorn syndrome candidate 1 protein isofor...
WHSC1L1               0.047   WHSC1L1 protein isoform long 
SUV39H2               0.047   suppressor of variegation 3-9 homolog 2 
MLL4                  0.047   myeloid/lymphoid or mixed-lineage leukemia 4 
MLL3                  0.047   myeloid/lymphoid or mixed-lineage leukemia 3 
MLL2                  0.045   myeloid/lymphoid or mixed-lineage leukemia 2 
EHMT2                 0.044   euchromatic histone-lysine N-methyltransferase 2 is...
EHMT2                 0.044   euchromatic histone-lysine N-methyltransferase 2 is...
EHMT1                 0.038   euchromatic histone-lysine N-methyltransferase 1 is...
SETMAR                0.033   SET domain and mariner transposase fusion 
SETD8                 0.027   SET domain-containing 8 
SETDB1                0.016   SET domain, bifurcated 1 isoform 2 
SETDB1                0.016   SET domain, bifurcated 1 isoform 1 
SETDB2                0.015   SET domain, bifurcated 2 isoform b 
SETDB2                0.015   SET domain, bifurcated 2 isoform a 
SETD5                 0.012   SET domain containing 5 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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