Guide to the Human Genome
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Name: MLL Sequence: fasta or formatted (3969aa) NCBI GI: 56550039
Description:

myeloid/lymphoid or mixed-lineage leukemia protein

Referenced in:

Histones, Related Proteins, and Modifying Enzymes
Additional Genes in Development
PHD Finger Proteins
Peptide-processing Enzymes
Wnt Signals

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.6        222           7
 C cysteine            2.0         80           2
 D aspartate           4.6        181           4
 E glutamate           6.3        251           5
 F phenylalanine       2.5        101           2
 G glycine             6.2        246           7
 H histidine           2.1         84           2
 I isoleucine          3.8        149           2
 K lysine              7.7        306           4
 L leucine             7.0        279           3
 M methionine          1.6         64           2
 N asparagine          4.0        158           3
 P proline             9.0        358           4
 Q glutamine           4.6        182           3
 R arginine            5.8        229           3
 S serine             13.7        544           9
 T threonine           6.3        251           4
 V valine              5.3        210           2
 W tryptophan          0.5         21           1
 Y tyrosine            1.3         53           3
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   myeloid/lymphoid or mixed-lineage leukemia protein [... 
MLL4                  0.122   myeloid/lymphoid or mixed-lineage leukemia 4 
MLL3                  0.020   myeloid/lymphoid or mixed-lineage leukemia 3 
MLL2                  0.019   myeloid/lymphoid or mixed-lineage leukemia 2 
SETD1B                0.016   SET domain containing 1B 
SETD1A                0.016   SET domain containing 1A 
EZH2                  0.009   enhancer of zeste 2 isoform b 
EZH2                  0.009   enhancer of zeste 2 isoform a 
EZH1                  0.009   enhancer of zeste homolog 1 
MUC12                 0.009   PREDICTED: mucin 12 
ASH1L                 0.009   absent, small, or homeotic 1-like 
SETD2                 0.009   SET domain containing 2 
NSD1                  0.008   nuclear receptor binding SET domain protein 1 isofor...
NSD1                  0.008   nuclear receptor binding SET domain protein 1 isofor...
SUV39H2               0.008   suppressor of variegation 3-9 homolog 2 
WHSC1                 0.008   Wolf-Hirschhorn syndrome candidate 1 protein isoform...
WHSC1                 0.008   Wolf-Hirschhorn syndrome candidate 1 protein isoform...
WHSC1                 0.008   Wolf-Hirschhorn syndrome candidate 1 protein isoform...
WHSC1                 0.008   Wolf-Hirschhorn syndrome candidate 1 protein isofor...
MUC12                 0.008   PREDICTED: mucin 12, cell surface associated 
WHSC1L1               0.008   WHSC1L1 protein isoform long 
MUC4                  0.007   mucin 4 isoform a 
MBD1                  0.007   methyl-CpG binding domain protein 1 isoform 2 
SUV39H1               0.007   suppressor of variegation 3-9 homolog 1 
MUC16                 0.007   mucin 16 
MUC17                 0.007   mucin 17 
MBD1                  0.007   methyl-CpG binding domain protein 1 isoform PCM1 [Ho...
MBD1                  0.007   methyl-CpG binding domain protein 1 isoform 1 
AFF4                  0.007   ALL1 fused gene from 5q31 
LOC100133790          0.007   PREDICTED: intestinal mucin-like, partial 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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