BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit 4 [Homo sapiens] (414 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit ... 815 0.0 gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens] 800 0.0 gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo sapi... 724 0.0 gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens] 393 e-109 gi|169167838 PREDICTED: similar to hCG2002932 [Homo sapiens] 317 1e-86 gi|239748566 PREDICTED: similar to hCG2002932 [Homo sapiens] 317 1e-86 gi|239742549 PREDICTED: hypothetical protein LOC345645 [Homo sap... 317 1e-86 gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens] 316 2e-86 gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens] 316 3e-86 gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens] 306 3e-83 gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens] 285 5e-77 gi|157671927 spermatogenesis associated 5 [Homo sapiens] 223 2e-58 gi|6005942 valosin-containing protein [Homo sapiens] 195 6e-50 gi|5802970 AFG3 ATPase family gene 3-like 2 [Homo sapiens] 186 3e-47 gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens] 185 6e-47 gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens] 185 6e-47 gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens] 174 1e-43 gi|4507173 spastic paraplegia 7 isoform 1 [Homo sapiens] 170 2e-42 gi|4505725 peroxin1 [Homo sapiens] 157 1e-38 gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens] 157 2e-38 gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens] 155 6e-38 gi|21327685 YME1-like 1 isoform 1 [Homo sapiens] 152 7e-37 gi|7657689 YME1-like 1 isoform 3 [Homo sapiens] 152 7e-37 gi|31742536 fidgetin-like 1 [Homo sapiens] 151 1e-36 gi|112789543 fidgetin-like 1 [Homo sapiens] 151 1e-36 gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens] 150 3e-36 gi|5901990 katanin p60 subunit A 1 [Homo sapiens] 144 1e-34 gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens] 143 3e-34 gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens] 143 3e-34 gi|17865802 vacuolar protein sorting factor 4B [Homo sapiens] 138 1e-32 >gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit 4 [Homo sapiens] Length = 414 Score = 815 bits (2106), Expect = 0.0 Identities = 414/414 (100%), Positives = 414/414 (100%) Query: 1 MIPWHEAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDE 60 MIPWHEAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDE Sbjct: 1 MIPWHEAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDE 60 Query: 61 QKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELL 120 QKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELL Sbjct: 61 QKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELL 120 Query: 121 KPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELP 180 KPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELP Sbjct: 121 KPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELP 180 Query: 181 LTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGP 240 LTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGP Sbjct: 181 LTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGP 240 Query: 241 RMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVN 300 RMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVN Sbjct: 241 RMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVN 300 Query: 301 VKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYV 360 VKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYV Sbjct: 301 VKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYV 360 Query: 361 ARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK 414 ARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK Sbjct: 361 ARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK 414 >gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens] Length = 418 Score = 800 bits (2067), Expect = 0.0 Identities = 408/409 (99%), Positives = 409/409 (100%) Query: 6 EAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLK 65 +AQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLK Sbjct: 10 KAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLK 69 Query: 66 KEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNAS 125 KEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNAS Sbjct: 70 KEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNAS 129 Query: 126 VALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFE 185 VALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFE Sbjct: 130 VALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFE 189 Query: 186 LYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRD 245 LYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRD Sbjct: 190 LYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRD 249 Query: 246 VFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIM 305 VFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIM Sbjct: 250 VFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIM 309 Query: 306 ATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDK 365 ATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDK Sbjct: 310 ATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDK 369 Query: 366 ISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK 414 ISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK Sbjct: 370 ISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK 418 >gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo sapiens] Length = 387 Score = 724 bits (1869), Expect = 0.0 Identities = 377/409 (92%), Positives = 378/409 (92%), Gaps = 31/409 (7%) Query: 6 EAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLK 65 +AQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYK Sbjct: 10 KAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYK------------------------ 45 Query: 66 KEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNAS 125 EEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNAS Sbjct: 46 -------EEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNAS 98 Query: 126 VALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFE 185 VALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFE Sbjct: 99 VALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFE 158 Query: 186 LYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRD 245 LYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRD Sbjct: 159 LYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRD 218 Query: 246 VFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIM 305 VFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIM Sbjct: 219 VFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIM 278 Query: 306 ATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDK 365 ATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDK Sbjct: 279 ATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDK 338 Query: 366 ISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK 414 ISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK Sbjct: 339 ISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK 387 >gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens] Length = 440 Score = 393 bits (1009), Expect = e-109 Identities = 187/369 (50%), Positives = 282/369 (76%), Gaps = 2/369 (0%) Query: 42 KLQQELEFLEVQEEYIKDEQ--KNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIV 99 KL++ ++L ++EE+I++++ K L+++ + +V ++ P+ +G E +D N AIV Sbjct: 64 KLERIKDYLLMEEEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSVGTLEEIIDDNHAIV 123 Query: 100 GSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVM 159 ++ GS +YV ILS +D++LL+P SV L+ +A++ VL + D + ++ ++ P Sbjct: 124 STSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQET 183 Query: 160 YADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHT 219 YADIGG+D Q QE++E+VELPLTH E Y+++GI PP+GV++YGPPG GKT+LAKAVA+ T Sbjct: 184 YADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQT 243 Query: 220 TAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADR 279 +A F+RVVGSE +QKYLG+GP++VR++FR+A+E+AP+I+FIDEIDAI TKR+D+ +G +R Sbjct: 244 SATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGER 303 Query: 280 EVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRL 339 E+QR +LELLNQ+DGFD +VKVIMATNR +TLDPAL+RPGR+DRKIEFPLPD + K+ Sbjct: 304 EIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKR 363 Query: 340 IFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAY 399 IF TS+M L+++V L+D + D +SGADI +IC E+G++A+RE R V +DF+K+ Sbjct: 364 IFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSK 423 Query: 400 KTVIKKDEQ 408 + V+ K ++ Sbjct: 424 ENVLYKKQE 432 >gi|169167838 PREDICTED: similar to hCG2002932 [Homo sapiens] Length = 415 Score = 317 bits (812), Expect = 1e-86 Identities = 157/371 (42%), Positives = 253/371 (68%), Gaps = 18/371 (4%) Query: 42 KLQQELEFLEVQEEYIKDEQ--KNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIV 99 KL++ ++L + EE+I++++ K L+++ + +V ++ P+ +G E +D N AIV Sbjct: 51 KLERIKDYLLMVEEFIRNQEQIKLLEEKQEEGRSKVDDLRGTPMSVGNLEEIIDDNHAIV 110 Query: 100 GSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVM 159 ++ GS +Y I+S ++++LL+P S+ L +A++ VL + + M+ ++ P Sbjct: 111 STSVGSEHYDSIISFVEKDLLEPGCSILLRHKVHAVIGVLMDDTGPLVTMMKVEKAPQET 170 Query: 160 YADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHT 219 Y + GG+D Q QE++E++ELPL H E Y+++G PP+GV++ GPPG Sbjct: 171 YVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPG-------------- 216 Query: 220 TAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADR 279 TA F+RVVGSE +QKYLG+GP++VR VF++A+E+AP+I+F DEI+AI TKR+D+ +G +R Sbjct: 217 TATFLRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGER 276 Query: 280 EVQRILLEL--LNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQK 337 E+Q+ +LEL LNQ+ GFD +VKVIMAT + +TLDP L+RPGR+D+KIEF LPD + K Sbjct: 277 EIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKTK 336 Query: 338 RLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEK 397 + IF TS+M L+ +V L+D + D SGADI +IC E+G++A+RE+R +DF+K Sbjct: 337 KHIFQIHTSRMTLANDVTLDDLIMAKDDFSGADIKAICTEAGLMALREHRMKATNEDFKK 396 Query: 398 AYKTVIKKDEQ 408 + ++V+ K + Sbjct: 397 SIESVLYKKHE 407 >gi|239748566 PREDICTED: similar to hCG2002932 [Homo sapiens] Length = 415 Score = 317 bits (812), Expect = 1e-86 Identities = 157/371 (42%), Positives = 253/371 (68%), Gaps = 18/371 (4%) Query: 42 KLQQELEFLEVQEEYIKDEQ--KNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIV 99 KL++ ++L + EE+I++++ K L+++ + +V ++ P+ +G E +D N AIV Sbjct: 51 KLERIKDYLLMVEEFIRNQEQIKLLEEKQEEGRSKVDDLRGTPMSVGNLEEIIDDNHAIV 110 Query: 100 GSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVM 159 ++ GS +Y I+S ++++LL+P S+ L +A++ VL + + M+ ++ P Sbjct: 111 STSVGSEHYDSIISFVEKDLLEPGCSILLRHKVHAVIGVLMDDTGPLVTMMKVEKAPQET 170 Query: 160 YADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHT 219 Y + GG+D Q QE++E++ELPL H E Y+++G PP+GV++ GPPG Sbjct: 171 YVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPG-------------- 216 Query: 220 TAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADR 279 TA F+RVVGSE +QKYLG+GP++VR VF++A+E+AP+I+F DEI+AI TKR+D+ +G +R Sbjct: 217 TATFLRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGER 276 Query: 280 EVQRILLEL--LNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQK 337 E+Q+ +LEL LNQ+ GFD +VKVIMAT + +TLDP L+RPGR+D+KIEF LPD + K Sbjct: 277 EIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKTK 336 Query: 338 RLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEK 397 + IF TS+M L+ +V L+D + D SGADI +IC E+G++A+RE+R +DF+K Sbjct: 337 KHIFQIHTSRMTLANDVTLDDLIMAKDDFSGADIKAICTEAGLMALREHRMKATNEDFKK 396 Query: 398 AYKTVIKKDEQ 408 + ++V+ K + Sbjct: 397 SIESVLYKKHE 407 >gi|239742549 PREDICTED: hypothetical protein LOC345645 [Homo sapiens] Length = 415 Score = 317 bits (812), Expect = 1e-86 Identities = 157/371 (42%), Positives = 253/371 (68%), Gaps = 18/371 (4%) Query: 42 KLQQELEFLEVQEEYIKDEQ--KNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIV 99 KL++ ++L + EE+I++++ K L+++ + +V ++ P+ +G E +D N AIV Sbjct: 51 KLERIKDYLLMVEEFIRNQEQIKLLEEKQEEGRSKVDDLRGTPMSVGNLEEIIDDNHAIV 110 Query: 100 GSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVM 159 ++ GS +Y I+S ++++LL+P S+ L +A++ VL + + M+ ++ P Sbjct: 111 STSVGSEHYDSIISFVEKDLLEPGCSILLRHKVHAVIGVLMDDTGPLVTMMKVEKAPQET 170 Query: 160 YADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHT 219 Y + GG+D Q QE++E++ELPL H E Y+++G PP+GV++ GPPG Sbjct: 171 YVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPG-------------- 216 Query: 220 TAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADR 279 TA F+RVVGSE +QKYLG+GP++VR VF++A+E+AP+I+F DEI+AI TKR+D+ +G +R Sbjct: 217 TATFLRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGER 276 Query: 280 EVQRILLEL--LNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQK 337 E+Q+ +LEL LNQ+ GFD +VKVIMAT + +TLDP L+RPGR+D+KIEF LPD + K Sbjct: 277 EIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKTK 336 Query: 338 RLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEK 397 + IF TS+M L+ +V L+D + D SGADI +IC E+G++A+RE+R +DF+K Sbjct: 337 KHIFQIHTSRMTLANDVTLDDLIMAKDDFSGADIKAICTEAGLMALREHRMKATNEDFKK 396 Query: 398 AYKTVIKKDEQ 408 + ++V+ K + Sbjct: 397 SIESVLYKKHE 407 >gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens] Length = 439 Score = 316 bits (810), Expect = 2e-86 Identities = 159/400 (39%), Positives = 246/400 (61%), Gaps = 20/400 (5%) Query: 34 EDLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVD 93 E++ R + L E++ ++ + + E + +K + E++K +++P ++ +E +D Sbjct: 39 EEIIQRTRLLDSEIKIMKSEVLRVTHELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLD 98 Query: 94 QNT--------------------AIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSN 133 + A++ ++T Y++ ++ +D E LKP V ++K S Sbjct: 99 VDPNDQEEDGANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSY 158 Query: 134 ALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGID 193 +++ LP E DS + + D++P Y+DIGG+D Q QE+ EA+ LP+ H E ++ +GI Sbjct: 159 LILETLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQ 218 Query: 194 PPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKEN 253 PP+GVLMYGPPG GKT+LA+A A T A F+++ G + VQ ++G+G ++VRD F LAKE Sbjct: 219 PPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEK 278 Query: 254 APAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTL 313 AP+IIFIDE+DAI TKRFD++ DREVQR +LELLNQ+DGF N VKVI ATNR D L Sbjct: 279 APSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKVIAATNRVDIL 338 Query: 314 DPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINS 373 DPALLR GRLDRKIEFP+P+ + I + KMN+S +V+ E+ D +GA + Sbjct: 339 DPALLRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKA 398 Query: 374 ICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFY 413 +C E+GM+A+R + +D+ + V K + ++Y Sbjct: 399 VCVEAGMIALRRGATELTHEDYMEGILEVQAKKKANLQYY 438 >gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens] Length = 406 Score = 316 bits (809), Expect = 3e-86 Identities = 170/396 (42%), Positives = 247/396 (62%), Gaps = 14/396 (3%) Query: 27 GPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQ------------EE 74 GPE +LE+ + Q L +E + + D+ +NL++ L AQ EE Sbjct: 5 GPEQMELEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRR--LQAQRNELNAKVRLLREE 62 Query: 75 VKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNA 134 ++ +Q +G+ + A+D+ +V + V + ID + PN VAL S Sbjct: 63 LQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYT 122 Query: 135 LVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDP 194 L +LP + D + ++ ++ PD Y IGG+D Q +E++E +ELP+ H EL++ +GI Sbjct: 123 LHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQ 182 Query: 195 PRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENA 254 P+GVL+YGPPG GKT+LA+AVAHHT FIRV GSE VQK++GEG RMVR++F +A+E+A Sbjct: 183 PKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHA 242 Query: 255 PAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLD 314 P+IIF+DEID+I + R + +G D EVQR +LELLNQ+DGF+ N+KVIMATNR D LD Sbjct: 243 PSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILD 302 Query: 315 PALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSI 374 ALLRPGR+DRKIEFP P+ + I + KMNL+ ++L SGA++ + Sbjct: 303 SALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGV 362 Query: 375 CQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEH 410 C E+GM A+RE R V +DFE A V++KD +++ Sbjct: 363 CTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKN 398 >gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens] Length = 403 Score = 306 bits (783), Expect = 3e-83 Identities = 158/382 (41%), Positives = 241/382 (63%), Gaps = 4/382 (1%) Query: 28 PEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQ 87 P + L+D Y+K E + ++ + + ++++ K L K++ ++ ++K +QS+ ++G+ Sbjct: 18 PRDKALQD----YRKKLLEHKEIDGRLKELREQLKELTKQYEKSENDLKALQSVGQIVGE 73 Query: 88 FLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSI 147 L+ + + IV +T G Y V +D+ LKP VAL + ++ LP E D + Sbjct: 74 VLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLV 133 Query: 148 MMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCG 207 ++ + +V Y++IGG+ Q +E+RE +ELPLT+ EL++++GI PP+G L+YGPPG G Sbjct: 134 YNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTG 193 Query: 208 KTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIA 267 KT+LA+AVA F++VV S V KY+GE R++R++F A+++ P IIF+DEIDAI Sbjct: 194 KTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIG 253 Query: 268 TKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKI 327 +RF T ADRE+QR L+ELLNQMDGFD VK+IMATNR DTLDPALLRPGRLDRKI Sbjct: 254 GRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKI 313 Query: 328 EFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENR 387 LP+ + + I + E+D E V D +GAD+ ++C E+GM A+R + Sbjct: 314 HIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADH 373 Query: 388 YIVLAKDFEKAYKTVIKKDEQE 409 V+ +DF KA + V + E Sbjct: 374 DFVVQEDFMKAVRKVADSKKLE 395 >gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens] Length = 433 Score = 285 bits (729), Expect = 5e-77 Identities = 140/266 (52%), Positives = 184/266 (69%) Query: 139 LPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGV 198 LPP+ D ++ M+ ++KPDV Y+D+GG Q +++RE VE PL H E + +GI+PP+GV Sbjct: 153 LPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGV 212 Query: 199 LMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAII 258 L++GPPG GKT+ A+AVA+ T A FIRV+GSE VQKY+GEG RMVR++F +A+ +I Sbjct: 213 LLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLI 272 Query: 259 FIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALL 318 F DEIDAI RFD G D EVQR +LEL+NQ+DGFD N+KV+MATNR DTLDPAL+ Sbjct: 273 FFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALM 332 Query: 319 RPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQES 378 RPGRLDRKIEF LPD + IF M++ ++ E +GA+I S+C E+ Sbjct: 333 RPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEA 392 Query: 379 GMLAVRENRYIVLAKDFEKAYKTVIK 404 GM A+R R I KDF +A VIK Sbjct: 393 GMFAIRARRKIATEKDFLEAVNKVIK 418 >gi|157671927 spermatogenesis associated 5 [Homo sapiens] Length = 893 Score = 223 bits (568), Expect = 2e-58 Identities = 120/292 (41%), Positives = 183/292 (62%), Gaps = 9/292 (3%) Query: 126 VALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFE 185 + L A+ D+ P S M + P+V ++DIGG++ K ++ +AVE PL H E Sbjct: 597 ITLKDFLQAMNDIRP-----SAMREIAIDVPNVSWSDIGGLESIKLKLEQAVEWPLKHPE 651 Query: 186 LYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRD 245 + ++GI PP+GVL+YGPPGC KTM+AKA+A+ + F+ + G E + KY+GE R VR+ Sbjct: 652 SFIRMGIQPPKGVLLYGPPGCSKTMIAKALANESGLNFLAIKGPELMNKYVGESERAVRE 711 Query: 246 VFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIM 305 FR A+ AP+IIF DE+DA+A +R + GA R+L +LL +MDG +Q +V ++ Sbjct: 712 TFRKARAVAPSIIFFDELDALAVER-GSSLGAGNVADRVLAQLLTEMDGIEQLKDVTILA 770 Query: 306 ATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDK 365 ATNR D +D AL+RPGR+DR I PLPD +R IF M +S EVDL++ + + D Sbjct: 771 ATNRPDRIDKALMRPGRIDRIIYVPLPDAATRREIFKLQFHSMPVSNEVDLDELILQTDA 830 Query: 366 ISGADINSICQESGMLAVREN--RYIVLAKDFEKAYKTVIKK-DEQEHEFYK 414 SGA+I ++C+E+ +LA+ E+ +++ + F +A TV + E FY+ Sbjct: 831 YSGAEIVAVCREAALLALEEDIQANLIMKRHFTQALSTVTPRIPESLRRFYE 882 Score = 162 bits (410), Expect = 5e-40 Identities = 95/236 (40%), Positives = 135/236 (57%), Gaps = 7/236 (2%) Query: 153 DQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLA 212 D + V Y IGG+ Q + +RE +ELPL EL+K GI PRGVL+YGPPG GKTM+A Sbjct: 345 DNQFKVTYDMIGGLSSQLKAIREIIELPLKQPELFKSYGIPAPRGVLLYGPPGTGKTMIA 404 Query: 213 KAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFD 272 +AVA+ A + G E + K+ GE +R +F A P+IIFIDE+DA+ KR Sbjct: 405 RAVANEVGAYVSVINGPEIISKFYGETEAKLRQIFAEATLRHPSIIFIDELDALCPKREG 464 Query: 273 AQTGADREVQRILLELLNQMDGFDQNVN---VKVIMATNRADTLDPALLRPGRLDRKIEF 329 AQ ++ R++ LL MDG V+ V V+ ATNR LD AL RPGR D++IE Sbjct: 465 AQNEVEK---RVVASLLTLMDGIGSEVSEGQVLVLGATNRPHALDAALRRPGRFDKEIEI 521 Query: 330 PLPDRRQKRLIFSTITSKM-NLSEEVDLEDYVARPDKISGADINSICQESGMLAVR 384 +P+ + + I + ++ +L E +L GAD+ +C E+G+ A+R Sbjct: 522 GVPNAQDRLDILQKLLRRVPHLLTEAELLQLANSAHGYVGADLKVLCNEAGLCALR 577 >gi|6005942 valosin-containing protein [Homo sapiens] Length = 806 Score = 195 bits (496), Expect = 6e-50 Identities = 98/245 (40%), Positives = 150/245 (61%) Query: 142 EADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMY 201 +++ S + T + P V + DIGG++ K+E++E V+ P+ H + + + G+ P +GVL Y Sbjct: 458 QSNPSALRETVVEVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFY 517 Query: 202 GPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFID 261 GPPGCGKT+LAKA+A+ A FI + G E + + GE VR++F A++ AP ++F D Sbjct: 518 GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFD 577 Query: 262 EIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPG 321 E+D+IA R R++ ++L +MDG NV +I ATNR D +DPA+LRPG Sbjct: 578 ELDSIAKARGGNIGDGGGAADRVINQILTEMDGMSTKKNVFIIGATNRPDIIDPAILRPG 637 Query: 322 RLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGML 381 RLD+ I PLPD + + I K ++++VDLE + SGAD+ ICQ + L Sbjct: 638 RLDQLIYIPLPDEKSRVAILKANLRKSPVAKDVDLEFLAKMTNGFSGADLTEICQRACKL 697 Query: 382 AVREN 386 A+RE+ Sbjct: 698 AIRES 702 Score = 195 bits (495), Expect = 7e-50 Identities = 104/238 (43%), Positives = 148/238 (62%), Gaps = 3/238 (1%) Query: 157 DVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVA 216 +V Y DIGG Q +++E VELPL H L+K IG+ PPRG+L+YGPPG GKT++A+AVA Sbjct: 200 EVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVA 259 Query: 217 HHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTG 276 + T A F + G E + K GE +R F A++NAPAIIFIDE+DAIA KR Sbjct: 260 NETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGE 319 Query: 277 ADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQ 336 +R RI+ +LL MDG Q +V V+ ATNR +++DPAL R GR DR+++ +PD Sbjct: 320 VER---RIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATG 376 Query: 337 KRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKD 394 + I T M L+++VDLE GAD+ ++C E+ + A+R+ ++ +D Sbjct: 377 RLEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAALQAIRKKMDLIDLED 434 >gi|5802970 AFG3 ATPase family gene 3-like 2 [Homo sapiens] Length = 797 Score = 186 bits (472), Expect = 3e-47 Identities = 104/252 (41%), Positives = 148/252 (58%), Gaps = 7/252 (2%) Query: 157 DVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVA 216 DV + D+ G + K E+ E V L + + Y+ +G P+G ++ GPPG GKT+LAKA A Sbjct: 304 DVKFKDVAGCEEAKLEIMEFVNF-LKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATA 362 Query: 217 HHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTG 276 FI V GSEF++ ++G GP VRD+F LA++NAP I+FIDEIDA+ KR G Sbjct: 363 GEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFG 422 Query: 277 ADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQ 336 E + L +LL +MDGF+ NV ++ TNR D LDPALLRPGR DR+I PD + Sbjct: 423 GQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKG 482 Query: 337 KRLIFSTITSKMNLSEEVDLEDYVAR-----PDKISGADINSICQESGMLAVRENRYIVL 391 + IF + L ++ +D +AR SGAD+ ++C E+ ++A R + Sbjct: 483 RASIFKVHLRPLKLDSTLE-KDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDSIN 541 Query: 392 AKDFEKAYKTVI 403 K FE+A + VI Sbjct: 542 QKHFEQAIERVI 553 >gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens] Length = 750 Score = 185 bits (470), Expect = 6e-47 Identities = 108/276 (39%), Positives = 166/276 (60%), Gaps = 23/276 (8%) Query: 156 PDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAV 215 P+V +ADIG ++ ++E+ A+ P+ + + +K +G+ P GVL+ GPPGCGKT+LAKAV Sbjct: 470 PNVTWADIGALEDIREELTMAILAPVRNPDQFKALGLVTPAGVLLAGPPGCGKTLLAKAV 529 Query: 216 AHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQT 275 A+ + FI V G E + Y+GE R VR VF+ AK +AP +IF DE+DA+ +R D +T Sbjct: 530 ANESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDALCPRRSDRET 589 Query: 276 GADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRR 335 GA R++ +LL +MDG + V ++ ATNR D +DPA+LRPGRLD+ + LP Sbjct: 590 GAS---VRVVNQLLTEMDGLEARQQVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPPPA 646 Query: 336 QKRLIFSTIT---SKMNLSEEVDLEDYVA--RPDKISGADINSICQESGMLAVRE----- 385 + I TIT +K L +V+LE R D +GAD++++ +E+ + A+R+ Sbjct: 647 DRLAILKTITKNGTKPPLDADVNLEAIAGDLRCDCYTGADLSALVREASICALRQEMARQ 706 Query: 386 ------NRYIVLAKDFEKAYK----TVIKKDEQEHE 411 V K FE+A+K ++ KKD+ +E Sbjct: 707 KSGNEKGELKVSHKHFEEAFKKVRSSISKKDQIMYE 742 Score = 167 bits (424), Expect = 1e-41 Identities = 94/244 (38%), Positives = 139/244 (56%), Gaps = 3/244 (1%) Query: 154 QKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAK 213 Q +V + D+GG D+ +EV + + + + H E+Y +G+ PPRGVL++GPPGCGKT+LA Sbjct: 152 QISNVKFEDVGGNDMTLKEVCKML-IHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAH 210 Query: 214 AVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDA 273 A+A ++V E V GE + +R++F A NAP IIFIDEIDAI KR A Sbjct: 211 AIAGELDLPILKVAAPEIVSGVSGESEQKLRELFEQAVSNAPCIIFIDEIDAITPKREVA 270 Query: 274 QTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPD 333 +R + LL ++ ++ V VI ATNR D+LDPAL R GR DR+I +PD Sbjct: 271 SKDMERRIVAQLLTCMDDLNNVAATARVLVIGATNRPDSLDPALRRAGRFDREICLGIPD 330 Query: 334 RRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAK 393 + I T+ K+ L + D GAD+ ++C+E+ M AV NR ++ + Sbjct: 331 EASRERILQTLCRKLRLPQAFDFCHLAHLTPGFVGADLMALCREAAMCAV--NRVLMKLQ 388 Query: 394 DFEK 397 + +K Sbjct: 389 EQQK 392 >gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens] Length = 856 Score = 185 bits (470), Expect = 6e-47 Identities = 108/276 (39%), Positives = 166/276 (60%), Gaps = 23/276 (8%) Query: 156 PDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAV 215 P+V +ADIG ++ ++E+ A+ P+ + + +K +G+ P GVL+ GPPGCGKT+LAKAV Sbjct: 576 PNVTWADIGALEDIREELTMAILAPVRNPDQFKALGLVTPAGVLLAGPPGCGKTLLAKAV 635 Query: 216 AHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQT 275 A+ + FI V G E + Y+GE R VR VF+ AK +AP +IF DE+DA+ +R D +T Sbjct: 636 ANESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDALCPRRSDRET 695 Query: 276 GADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRR 335 GA R++ +LL +MDG + V ++ ATNR D +DPA+LRPGRLD+ + LP Sbjct: 696 GAS---VRVVNQLLTEMDGLEARQQVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPPPA 752 Query: 336 QKRLIFSTIT---SKMNLSEEVDLEDYVA--RPDKISGADINSICQESGMLAVRE----- 385 + I TIT +K L +V+LE R D +GAD++++ +E+ + A+R+ Sbjct: 753 DRLAILKTITKNGTKPPLDADVNLEAIAGDLRCDCYTGADLSALVREASICALRQEMARQ 812 Query: 386 ------NRYIVLAKDFEKAYK----TVIKKDEQEHE 411 V K FE+A+K ++ KKD+ +E Sbjct: 813 KSGNEKGELKVSHKHFEEAFKKVRSSISKKDQIMYE 848 Score = 167 bits (424), Expect = 1e-41 Identities = 94/244 (38%), Positives = 139/244 (56%), Gaps = 3/244 (1%) Query: 154 QKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAK 213 Q +V + D+GG D+ +EV + + + + H E+Y +G+ PPRGVL++GPPGCGKT+LA Sbjct: 258 QISNVKFEDVGGNDMTLKEVCKML-IHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAH 316 Query: 214 AVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDA 273 A+A ++V E V GE + +R++F A NAP IIFIDEIDAI KR A Sbjct: 317 AIAGELDLPILKVAAPEIVSGVSGESEQKLRELFEQAVSNAPCIIFIDEIDAITPKREVA 376 Query: 274 QTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPD 333 +R + LL ++ ++ V VI ATNR D+LDPAL R GR DR+I +PD Sbjct: 377 SKDMERRIVAQLLTCMDDLNNVAATARVLVIGATNRPDSLDPALRRAGRFDREICLGIPD 436 Query: 334 RRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAK 393 + I T+ K+ L + D GAD+ ++C+E+ M AV NR ++ + Sbjct: 437 EASRERILQTLCRKLRLPQAFDFCHLAHLTPGFVGADLMALCREAAMCAV--NRVLMKLQ 494 Query: 394 DFEK 397 + +K Sbjct: 495 EQQK 498 >gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens] Length = 753 Score = 174 bits (441), Expect = 1e-43 Identities = 104/286 (36%), Positives = 167/286 (58%), Gaps = 25/286 (8%) Query: 139 LPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGV 198 + P + S++ L D KP V + +IGG++ K ++++++E PL + ++G+ P+GV Sbjct: 444 IQPSSFRSVIGLM-DIKP-VDWEEIGGLEDVKLKLKQSIEWPLKFPWEFVRMGLTQPKGV 501 Query: 199 LMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAII 258 L+YGPPGC KT L +A+A +F+ V G++ ++G+ +++ +FR A+ + PAI+ Sbjct: 502 LLYGPPGCAKTTLVRALATSCHCSFVSVSGADLFSPFVGDSEKVLSQIFRQARASTPAIL 561 Query: 259 FIDEIDAIATKRFDAQTGADREVQRILLELLNQMDG-----------------FDQ--NV 299 F+DEID+I R ++TG D + +R+L LLN++DG F + N Sbjct: 562 FLDEIDSILGARSASKTGCDVQ-ERVLSVLLNELDGVGLKTIERRGSKSSQQEFQEVFNR 620 Query: 300 NVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDY 359 +V +I ATNR D LD ALLRPGRLD+ I P PD + + I T M + +V LE+ Sbjct: 621 SVMIIAATNRPDVLDTALLRPGRLDKIIYIPPPDHKGRLSILKVCTKTMPIGPDVSLENL 680 Query: 360 VARPDKISGADINSICQESGMLAVREN---RYIVLAKDFEKAYKTV 402 A SGAD+ ++C E+ +LA++EN V + F K+ KTV Sbjct: 681 AAETCFFSGADLRNLCTEAALLALQENGLDATTVKQEHFLKSLKTV 726 Score = 145 bits (366), Expect = 7e-35 Identities = 88/248 (35%), Positives = 134/248 (54%), Gaps = 13/248 (5%) Query: 163 IGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAA 222 +GG+ +RE + LPL + +G+ PRGVL+ GPPG GKT L +AVA A Sbjct: 202 LGGLSEAADSLRELLRLPLRYPRALTALGLAVPRGVLLAGPPGVGKTQLVRAVAREAGAE 261 Query: 223 FIRVVGSEFVQKYLGEGPRMVRDVFRLAKENA---PAIIFIDEIDAIATKRFDAQTGADR 279 + V GE VR VF+ A+E A P+++F+DE+DA+ +R G+ Sbjct: 262 LLAVSAPALQGSRPGETEENVRRVFQRARELASRGPSLLFLDEMDALCPQR-----GSRA 316 Query: 280 EVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRL 339 R++ ++L +DG + V V+ ATNR D LDPAL RPGR DR++ P +Q++ Sbjct: 317 PESRVVAQVLTLLDGASGDREVVVVGATNRPDALDPALRRPGRFDREVVIGTPTLKQRKE 376 Query: 340 IFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAV-----RENRYIVLAKD 394 I ITSKM +S VDL GAD+ ++C+E+ M A+ ++ ++ D Sbjct: 377 ILQVITSKMPISSHVDLGLLAEMTVGYVGADLTALCREAAMHALLHSEKNQDNPVIDEID 436 Query: 395 FEKAYKTV 402 F +A+K + Sbjct: 437 FLEAFKNI 444 >gi|4507173 spastic paraplegia 7 isoform 1 [Homo sapiens] Length = 795 Score = 170 bits (430), Expect = 2e-42 Identities = 101/249 (40%), Positives = 143/249 (57%), Gaps = 4/249 (1%) Query: 158 VMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAH 217 V + D+ GM K EVRE V+ L E + Q+G P+G L+ GPPGCGKT+LAKAVA Sbjct: 306 VSFKDVAGMHEAKLEVREFVDY-LKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVAT 364 Query: 218 HTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTG- 276 F+ + G EFV+ G G VR +F+ A+ AP I++IDEIDA+ KR +G Sbjct: 365 EAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGF 424 Query: 277 ADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQ 336 ++ E ++ L +LL +MDG +V V+ +TNRAD LD AL+RPGRLDR + LP ++ Sbjct: 425 SNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLPTLQE 484 Query: 337 KRLIFSTITSKMNLSEEVDL--EDYVARPDKISGADINSICQESGMLAVRENRYIVLAKD 394 +R IF + L++ + SGADI +IC E+ + A RE V + Sbjct: 485 RREIFEQHLKSLKLTQSSTFYSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTLN 544 Query: 395 FEKAYKTVI 403 FE A + V+ Sbjct: 545 FEYAVERVL 553 >gi|4505725 peroxin1 [Homo sapiens] Length = 1283 Score = 157 bits (398), Expect = 1e-38 Identities = 83/239 (34%), Positives = 140/239 (58%), Gaps = 3/239 (1%) Query: 145 SSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPP 204 +S+ + + D+ + IGG+ +Q + + ++LP + EL+ + I G+L+YGPP Sbjct: 824 ASLRSVNLHKPRDLGWDKIGGLHEVRQILMDTIQLPAKYPELFANLPIRQRTGILLYGPP 883 Query: 205 GCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEID 264 G GKT+LA +A + FI V G E + KY+G + VRD+F A+ P I+F DE + Sbjct: 884 GTGKTLLAGVIARESRMNFISVKGPELLSKYIGASEQAVRDIFIRAQAAKPCILFFDEFE 943 Query: 265 AIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLD 324 +IA +R TG R++ +LL Q+DG + V V+ AT+R D +DPALLRPGRLD Sbjct: 944 SIAPRRGHDNTGV---TDRVVNQLLTQLDGVEGLQGVYVLAATSRPDLIDPALLRPGRLD 1000 Query: 325 RKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAV 383 + + P PD+ + I + ++ + L+++VDL+ + D +GAD+ ++ + + A+ Sbjct: 1001 KCVYCPPPDQVSRLEILNVLSDSLPLADDVDLQHVASVTDSFTGADLKALLYNAQLEAL 1059 >gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens] Length = 980 Score = 157 bits (397), Expect = 2e-38 Identities = 93/232 (40%), Positives = 140/232 (60%), Gaps = 7/232 (3%) Query: 156 PDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAV 215 P V + D+GG+ K+E+ E ++LPL H EL +G+ G+L++GPPG GKT+LAKAV Sbjct: 700 PSVSWHDVGGLQEVKKEILETIQLPLEHPELLS-LGLRRS-GLLLHGPPGTGKTLLAKAV 757 Query: 216 AHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQT 275 A + F+ V G E + Y+G+ VR+VF A+ AP IIF DE+D++A R ++ Sbjct: 758 ATECSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSR--GRS 815 Query: 276 GADREV-QRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDR 334 G V R++ +LL ++DG +V VI ATNR D LDPALLRPGR D+ + + Sbjct: 816 GDSGGVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLRPGRFDKLVFVGANED 875 Query: 335 RQKRL-IFSTITSKMNLSEEVDLEDYV-ARPDKISGADINSICQESGMLAVR 384 R +L + S IT K L V L + + P +++GAD+ S+C ++ A++ Sbjct: 876 RASQLRVLSAITRKFKLEPSVSLVNVLDCCPPQLTGADLYSLCSDAMTAALK 927 Score = 63.5 bits (153), Expect = 3e-10 Identities = 48/185 (25%), Positives = 80/185 (43%), Gaps = 4/185 (2%) Query: 198 VLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAI 257 VL+ GPPGCGKT + A H ++V S + G ++ +F A+ PA+ Sbjct: 466 VLLRGPPGCGKTTVVAAACSHLGLHLLKVPCSSLCAESSGAVETKLQAIFSRARRCRPAV 525 Query: 258 IFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPAL 317 + + +D + R G D V +L LL D + + V+ T+RA L PA Sbjct: 526 LLLTAVDLLGRDR--DGLGEDARVMAVLRHLLLNEDPLNSCPPLMVVATTSRAQDL-PAD 582 Query: 318 LRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQE 377 ++ ++E P Q+ I +T+ + L +EV+L R D+ ++ Sbjct: 583 VQTA-FPHELEVPALSEGQRLSILRALTAHLPLGQEVNLAQLARRCAGFVVGDLYALLTH 641 Query: 378 SGMLA 382 S A Sbjct: 642 SSRAA 646 >gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens] Length = 1390 Score = 155 bits (392), Expect = 6e-38 Identities = 104/297 (35%), Positives = 152/297 (51%), Gaps = 36/297 (12%) Query: 134 ALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGID 193 +L DV P + DSS V + +GG+ ++E V PL + E++++ I Sbjct: 410 SLADVDPMQLDSS-----------VRFDSVGGLSNHIAALKEMVVFPLLYPEVFEKFKIQ 458 Query: 194 PPRGVLMYGPPGCGKTMLAKAVAHHTT-----AAFIRVVGSEFVQKYLGEGPRMVRDVFR 248 PPRG L YGPPG GKT++A+A+A+ + AF G++ + K++GE R +R +F Sbjct: 459 PPRGCLFYGPPGTGKTLVARALANECSQGDKRVAFFMRKGADCLSKWVGESERQLRLLFD 518 Query: 249 LAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATN 308 A + P+IIF DEID +A R Q D+ I+ LL MDG D + VI ATN Sbjct: 519 QAYQMRPSIIFFDEIDGLAPVRSSRQ---DQIHSSIVSTLLALMDGLDSRGEIVVIGATN 575 Query: 309 RADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSE-EVDLEDYVARPDKIS 367 R D++DPAL RPGR DR+ F LPD+ ++ I T N + LE+ Sbjct: 576 RLDSIDPALRRPGRFDREFLFSLPDKEARKEILKIHTRDWNPKPLDTFLEELAENCVGYC 635 Query: 368 GADINSICQESGMLAVRE----------------NRYIVLAKDFEKAYKTVIKKDEQ 408 GADI SIC E+ + A+R + + AKDFE A + +I ++ Sbjct: 636 GADIKSICAEAALCALRRRYPQIYTTSEKLQLDLSSINISAKDFEVAMQKMIPASQR 692 >gi|21327685 YME1-like 1 isoform 1 [Homo sapiens] Length = 773 Score = 152 bits (383), Expect = 7e-37 Identities = 86/255 (33%), Positives = 144/255 (56%), Gaps = 3/255 (1%) Query: 154 QKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAK 213 Q +V + + G++ KQE++E VE L + + + +G P+G+L+ GPPG GKT+LA+ Sbjct: 332 QMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLAR 390 Query: 214 AVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDA 273 AVA F GSEF + ++G G +R++FR AK NAP +IFIDE+D++ KR ++ Sbjct: 391 AVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIES 450 Query: 274 QTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPD 333 ++ + +LL +MDGF N V +I ATN + LD AL+RPGR D ++ P PD Sbjct: 451 P--MHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPD 508 Query: 334 RRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAK 393 + + I +K+ + VD E SGA++ ++ ++ + A + + +V K Sbjct: 509 VKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMK 568 Query: 394 DFEKAYKTVIKKDEQ 408 + E + ++ E+ Sbjct: 569 ELEFSKDKILMGPER 583 >gi|7657689 YME1-like 1 isoform 3 [Homo sapiens] Length = 716 Score = 152 bits (383), Expect = 7e-37 Identities = 86/255 (33%), Positives = 144/255 (56%), Gaps = 3/255 (1%) Query: 154 QKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAK 213 Q +V + + G++ KQE++E VE L + + + +G P+G+L+ GPPG GKT+LA+ Sbjct: 275 QMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLAR 333 Query: 214 AVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDA 273 AVA F GSEF + ++G G +R++FR AK NAP +IFIDE+D++ KR ++ Sbjct: 334 AVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIES 393 Query: 274 QTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPD 333 ++ + +LL +MDGF N V +I ATN + LD AL+RPGR D ++ P PD Sbjct: 394 P--MHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPD 451 Query: 334 RRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAK 393 + + I +K+ + VD E SGA++ ++ ++ + A + + +V K Sbjct: 452 VKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMK 511 Query: 394 DFEKAYKTVIKKDEQ 408 + E + ++ E+ Sbjct: 512 ELEFSKDKILMGPER 526 >gi|31742536 fidgetin-like 1 [Homo sapiens] Length = 674 Score = 151 bits (381), Expect = 1e-36 Identities = 95/280 (33%), Positives = 152/280 (54%), Gaps = 23/280 (8%) Query: 139 LPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGV 198 L P+ IM D P V + DI G++ K ++E V P+ +++ + PP+G+ Sbjct: 379 LEPKMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLR-GPPKGI 437 Query: 199 LMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAII 258 L++GPPG GKT++ K +A + A F + S K++GEG +MVR +F +A+ PA+I Sbjct: 438 LLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVI 497 Query: 259 FIDEIDAIATKRFDAQTGADREVQRILLELLNQMDG--FDQNVNVKVIMATNRADTLDPA 316 FIDEID++ ++R D + + R RI E L Q+DG + V+ ATNR +D A Sbjct: 498 FIDEIDSLLSQRGDGEHESSR---RIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEA 554 Query: 317 LLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMN--LSEEVDLEDYVARPDKISGADINSI 374 R RL +++ PLP+ ++ I + SK LSEE ++E V + D SGAD+ + Sbjct: 555 ARR--RLVKRLYIPLPEASARKQIVINLMSKEQCCLSEE-EIEQIVQQSDAFSGADMTQL 611 Query: 375 CQESGMLAVRENRYIVLAK------------DFEKAYKTV 402 C+E+ + +R + +A DFE A++TV Sbjct: 612 CREASLGPIRSLQTADIATITPDQVRPIAYIDFENAFRTV 651 >gi|112789543 fidgetin-like 1 [Homo sapiens] Length = 674 Score = 151 bits (381), Expect = 1e-36 Identities = 95/280 (33%), Positives = 152/280 (54%), Gaps = 23/280 (8%) Query: 139 LPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGV 198 L P+ IM D P V + DI G++ K ++E V P+ +++ + PP+G+ Sbjct: 379 LEPKMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLR-GPPKGI 437 Query: 199 LMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAII 258 L++GPPG GKT++ K +A + A F + S K++GEG +MVR +F +A+ PA+I Sbjct: 438 LLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVI 497 Query: 259 FIDEIDAIATKRFDAQTGADREVQRILLELLNQMDG--FDQNVNVKVIMATNRADTLDPA 316 FIDEID++ ++R D + + R RI E L Q+DG + V+ ATNR +D A Sbjct: 498 FIDEIDSLLSQRGDGEHESSR---RIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEA 554 Query: 317 LLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMN--LSEEVDLEDYVARPDKISGADINSI 374 R RL +++ PLP+ ++ I + SK LSEE ++E V + D SGAD+ + Sbjct: 555 ARR--RLVKRLYIPLPEASARKQIVINLMSKEQCCLSEE-EIEQIVQQSDAFSGADMTQL 611 Query: 375 CQESGMLAVRENRYIVLAK------------DFEKAYKTV 402 C+E+ + +R + +A DFE A++TV Sbjct: 612 CREASLGPIRSLQTADIATITPDQVRPIAYIDFENAFRTV 651 >gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens] Length = 1458 Score = 150 bits (378), Expect = 3e-36 Identities = 101/280 (36%), Positives = 147/280 (52%), Gaps = 29/280 (10%) Query: 111 ILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQK 170 + S I RE +K AS+A DV P D S V + IGG+ Sbjct: 370 LASGILRERVKVGASLA---------DVDPMNIDKS-----------VRFDSIGGLSHHI 409 Query: 171 QEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTT-----AAFIR 225 ++E V PL + E++++ I PPRG L YGPPG GKT++A+A+A+ + AF Sbjct: 410 HALKEMVVFPLLYPEIFEKFKIQPPRGCLFYGPPGTGKTLVARALANECSQGDKKVAFFM 469 Query: 226 VVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRIL 285 G++ + K++GE R +R +F A P+IIF DEID +A R Q D+ I+ Sbjct: 470 RKGADCLSKWVGESERQLRLLFDQAYLMRPSIIFFDEIDGLAPVRSSRQ---DQIHSSIV 526 Query: 286 LELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTIT 345 LL MDG D + VI ATNR D++DPAL RPGR DR+ F LPD++ ++ I T Sbjct: 527 STLLALMDGLDNRGEIVVIGATNRLDSIDPALRRPGRFDREFLFNLPDQKARKHILQIHT 586 Query: 346 SKMNLS-EEVDLEDYVARPDKISGADINSICQESGMLAVR 384 N + L + + GADI ++C E+ ++A+R Sbjct: 587 RDWNPKLSDAFLGELAEKCVGYCGADIKALCTEAALIALR 626 >gi|5901990 katanin p60 subunit A 1 [Homo sapiens] Length = 491 Score = 144 bits (364), Expect = 1e-34 Identities = 92/239 (38%), Positives = 137/239 (57%), Gaps = 14/239 (5%) Query: 154 QKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAK 213 Q P+V + DI + K+ ++EAV LP+ E +K I P +GVLM GPPG GKT+LAK Sbjct: 202 QNPNVRWDDIADLVEAKKLLKEAVVLPMWMPEFFKGIR-RPWKGVLMVGPPGTGKTLLAK 260 Query: 214 AVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDA 273 AVA F V S KY GE ++VR +F +A+ +PA IFIDEID+I ++R Sbjct: 261 AVATECKTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYSPATIFIDEIDSICSRR--- 317 Query: 274 QTGADREV-QRILLELLNQMDGF-------DQNVNVKVIMATNRADTLDPALLRPGRLDR 325 T + E +R+ ELL QMDG D + V V+ ATN +D AL R RL++ Sbjct: 318 GTSEEHEASRRVKAELLVQMDGVGGTSENDDPSKMVMVLAATNFPWDIDEALRR--RLEK 375 Query: 326 KIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVR 384 +I PLP + + + ++ L+++VDL + SGADI ++C+++ ++A+R Sbjct: 376 RIYIPLPSAKGREELLRISLRELELADDVDLASIAENMEGYSGADITNVCRDASLMAMR 434 >gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens] Length = 490 Score = 143 bits (360), Expect = 3e-34 Identities = 91/239 (38%), Positives = 136/239 (56%), Gaps = 14/239 (5%) Query: 154 QKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAK 213 + P + + DI ++ K+ +REAV LP+ + +K I P +GVLM GPPG GKTMLAK Sbjct: 201 RNPSIHWDDIADLEEAKKLLREAVVLPMWMPDFFKGIR-RPWKGVLMVGPPGTGKTMLAK 259 Query: 214 AVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDA 273 AVA F V S KY GE ++VR +F +A+ AP IFIDEID+I ++R Sbjct: 260 AVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRR--- 316 Query: 274 QTGADREV-QRILLELLNQMDGF-------DQNVNVKVIMATNRADTLDPALLRPGRLDR 325 T + E +R+ ELL QMDG D + V V+ ATN +D AL R RL++ Sbjct: 317 GTSDEHEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDEALRR--RLEK 374 Query: 326 KIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVR 384 +I PLP + + + ++ L ++ LED + + SGADI ++C+++ ++A+R Sbjct: 375 RIYIPLPTAKGRAELLKINLREVELDPDIQLEDIAEKIEGYSGADITNVCRDASLMAMR 433 >gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens] Length = 490 Score = 143 bits (360), Expect = 3e-34 Identities = 91/239 (38%), Positives = 136/239 (56%), Gaps = 14/239 (5%) Query: 154 QKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAK 213 + P + + DI ++ K+ +REAV LP+ + +K I P +GVLM GPPG GKTMLAK Sbjct: 201 RNPSIHWDDIADLEEAKKLLREAVVLPMWMPDFFKGIR-RPWKGVLMVGPPGTGKTMLAK 259 Query: 214 AVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDA 273 AVA F V S KY GE ++VR +F +A+ AP IFIDEID+I ++R Sbjct: 260 AVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRR--- 316 Query: 274 QTGADREV-QRILLELLNQMDGF-------DQNVNVKVIMATNRADTLDPALLRPGRLDR 325 T + E +R+ ELL QMDG D + V V+ ATN +D AL R RL++ Sbjct: 317 GTSDEHEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDEALRR--RLEK 374 Query: 326 KIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVR 384 +I PLP + + + ++ L ++ LED + + SGADI ++C+++ ++A+R Sbjct: 375 RIYIPLPTAKGRAELLKINLREVELDPDIQLEDIAEKIEGYSGADITNVCRDASLMAMR 433 >gi|17865802 vacuolar protein sorting factor 4B [Homo sapiens] Length = 444 Score = 138 bits (347), Expect = 1e-32 Identities = 87/235 (37%), Positives = 139/235 (59%), Gaps = 9/235 (3%) Query: 154 QKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAK 213 ++P+V ++D+ G++ K+ ++EAV LP+ L+ P RG+L++GPPG GK+ LAK Sbjct: 127 ERPNVKWSDVAGLEGAKEALKEAVILPIKFPHLFTGKRT-PWRGILLFGPPGTGKSYLAK 185 Query: 214 AVAHHTT-AAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFD 272 AVA + F + S+ V K+LGE ++V+++F+LA+EN P+IIFIDEID++ R + Sbjct: 186 AVATEANNSTFFSISSSDLVSKWLGESEKLVKNLFQLARENKPSIIFIDEIDSLCGSRSE 245 Query: 273 AQTGADREVQRILLELLNQMDGFD-QNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPL 331 ++ A R RI E L QM G N + V+ ATN LD A+ R R +++I PL Sbjct: 246 NESEAAR---RIKTEFLVQMQGVGVDNDGILVLGATNIPWVLDSAIRR--RFEKRIYIPL 300 Query: 332 PDRRQKRLIFST-ITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRE 385 P+ + +F + + N E D + + D SGADI+ I +++ M VR+ Sbjct: 301 PEPHARAAMFKLHLGTTQNSLTEADFRELGRKTDGYSGADISIIVRDALMQPVRK 355 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.136 0.381 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,271,784 Number of Sequences: 37866 Number of extensions: 666904 Number of successful extensions: 3613 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 100 Number of HSP's successfully gapped in prelim test: 52 Number of HSP's that attempted gapping in prelim test: 3231 Number of HSP's gapped (non-prelim): 372 length of query: 414 length of database: 18,247,518 effective HSP length: 105 effective length of query: 309 effective length of database: 14,271,588 effective search space: 4409920692 effective search space used: 4409920692 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.