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Search of human proteins with 83582800
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|83582800 beta-defensin 116 [Homo sapiens]
(102 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|83582800 beta-defensin 116 [Homo sapiens] 216 2e-57
gi|23503331 defensin, beta 123 precursor [Homo sapiens] 47 2e-06
gi|58865339 defensin, beta 121 [Homo sapiens] 40 3e-04
gi|50344744 beta-defensin 108B [Homo sapiens] 39 9e-04
gi|239753808 PREDICTED: hypothetical protein [Homo sapiens] 37 0.003
gi|239748372 PREDICTED: hypothetical protein [Homo sapiens] 37 0.003
gi|169166494 PREDICTED: hypothetical protein [Homo sapiens] 37 0.003
gi|37704382 defensin, beta 119 isoform a precursor [Homo sapiens] 37 0.003
gi|83582798 beta-defensin 115 [Homo sapiens] 35 0.017
gi|21040279 defensin, beta 127 preproprotein [Homo sapiens] 34 0.022
gi|239749357 PREDICTED: hypothetical protein XP_002347009 [Homo ... 33 0.048
gi|16905373 beta-defensin 118 [Homo sapiens] 33 0.048
gi|82734223 beta-defensin 124 [Homo sapiens] 33 0.063
gi|62243658 PI-3-kinase-related kinase SMG-1 [Homo sapiens] 32 0.082
gi|103485139 defensin, beta 104A precursor [Homo sapiens] 32 0.082
gi|103485137 defensin, beta 104B precursor [Homo sapiens] 32 0.082
gi|13624333 defensin, beta 126 preproprotein [Homo sapiens] 30 0.53
gi|76563936 defensin, beta 125 preproprotein [Homo sapiens] 29 0.91
gi|74136827 beta-defensin 134 [Homo sapiens] 28 1.2
gi|83582796 beta-defensin 113 [Homo sapiens] 28 1.2
gi|82734214 beta-defensin 111 [Homo sapiens] 28 1.2
gi|46409558 beta-defensin 32 precursor [Homo sapiens] 28 1.6
gi|22748611 defensin, beta 106A precursor [Homo sapiens] 27 2.7
gi|23503329 defensin, beta 119 isoform c precursor [Homo sapiens] 27 2.7
gi|103485143 defensin, beta 106B precursor [Homo sapiens] 27 2.7
gi|169162343 PREDICTED: hypothetical protein [Homo sapiens] 27 3.5
gi|113411617 PREDICTED: hypothetical protein [Homo sapiens] 27 3.5
gi|82734217 beta-defensin 112 [Homo sapiens] 27 3.5
gi|32307109 WAP four-disulfide core domain 3 precursor [Homo sap... 27 3.5
gi|119395764 NLR family, pyrin domain containing 3 isoform a [Ho... 27 4.5
>gi|83582800 beta-defensin 116 [Homo sapiens]
Length = 102
Score = 216 bits (551), Expect = 2e-57
Identities = 102/102 (100%), Positives = 102/102 (100%)
Query: 1 MSVMKPCLMTIAILMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNACREYEIQYLT 60
MSVMKPCLMTIAILMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNACREYEIQYLT
Sbjct: 1 MSVMKPCLMTIAILMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNACREYEIQYLT 60
Query: 61 CPNDQKCCLKLSVKITSSKNVKEDYDSNSNLSVTNSSSYSHI 102
CPNDQKCCLKLSVKITSSKNVKEDYDSNSNLSVTNSSSYSHI
Sbjct: 61 CPNDQKCCLKLSVKITSSKNVKEDYDSNSNLSVTNSSSYSHI 102
>gi|23503331 defensin, beta 123 precursor [Homo sapiens]
Length = 67
Score = 47.4 bits (111), Expect = 2e-06
Identities = 27/67 (40%), Positives = 38/67 (56%), Gaps = 12/67 (17%)
Query: 4 MKPCLMTIAILMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNACREYEIQYLTCPN 63
MK L+T+ +L++L+Q TPGG R WN LY G CR C + E Y+ C N
Sbjct: 1 MKLLLLTLTVLLLLSQLTPGGTQRC--------WN---LY-GKCRYRCSKKERVYVYCIN 48
Query: 64 DQKCCLK 70
++ CC+K
Sbjct: 49 NKMCCVK 55
>gi|58865339 defensin, beta 121 [Homo sapiens]
Length = 76
Score = 40.4 bits (93), Expect = 3e-04
Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 14/66 (21%)
Query: 4 MKPCLMTIAILMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNACREYEIQYLTCPN 63
MK L+ + + ++LAQ TP GKS G CR C+E E+ Y+ C
Sbjct: 1 MKLLLLLLTVTLLLAQVTP---VMKCWGKS-----------GRCRTTCKESEVYYILCKT 46
Query: 64 DQKCCL 69
+ KCC+
Sbjct: 47 EAKCCV 52
>gi|50344744 beta-defensin 108B [Homo sapiens]
Length = 73
Score = 38.9 bits (89), Expect = 9e-04
Identities = 24/68 (35%), Positives = 31/68 (45%), Gaps = 9/68 (13%)
Query: 4 MKPCLMTIAILMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNACREYEIQYLTCPN 63
M+ ++ AI ++Q P GK +E CE G CR+ C E EI C N
Sbjct: 1 MRIAVLLFAIFFFMSQVLPA------RGKFKEI---CERPNGSCRDFCLETEIHVGRCLN 51
Query: 64 DQKCCLKL 71
Q CCL L
Sbjct: 52 SQPCCLPL 59
>gi|239753808 PREDICTED: hypothetical protein [Homo sapiens]
Length = 83
Score = 37.4 bits (85), Expect = 0.003
Identities = 23/70 (32%), Positives = 32/70 (45%), Gaps = 9/70 (12%)
Query: 2 SVMKPCLMTIAILMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNACREYEIQYLTC 61
S ++ ++ AI ++Q P GK +E CE G CR+ C E EI C
Sbjct: 9 SAVRIAVLLFAIFFFMSQVLPA------RGKFKEI---CERPNGSCRDFCLETEIHVGRC 59
Query: 62 PNDQKCCLKL 71
N + CCL L
Sbjct: 60 LNSRPCCLPL 69
>gi|239748372 PREDICTED: hypothetical protein [Homo sapiens]
Length = 83
Score = 37.4 bits (85), Expect = 0.003
Identities = 23/70 (32%), Positives = 32/70 (45%), Gaps = 9/70 (12%)
Query: 2 SVMKPCLMTIAILMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNACREYEIQYLTC 61
S ++ ++ AI ++Q P GK +E CE G CR+ C E EI C
Sbjct: 9 SAVRIAVLLFAIFFFMSQVLPA------RGKFKEI---CERPNGSCRDFCLETEIHVGRC 59
Query: 62 PNDQKCCLKL 71
N + CCL L
Sbjct: 60 LNSRPCCLPL 69
>gi|169166494 PREDICTED: hypothetical protein [Homo sapiens]
Length = 73
Score = 37.4 bits (85), Expect = 0.003
Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 9/68 (13%)
Query: 4 MKPCLMTIAILMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNACREYEIQYLTCPN 63
M+ ++ AI ++Q P GK +E CE G CR+ C E EI C N
Sbjct: 1 MRIAVLLFAIFFFMSQVLPA------RGKFKEI---CERPNGSCRDFCLETEIHVGRCLN 51
Query: 64 DQKCCLKL 71
+ CCL L
Sbjct: 52 SRPCCLPL 59
>gi|37704382 defensin, beta 119 isoform a precursor [Homo sapiens]
Length = 84
Score = 37.4 bits (85), Expect = 0.003
Identities = 16/39 (41%), Positives = 24/39 (61%)
Query: 40 CELYQGMCRNACREYEIQYLTCPNDQKCCLKLSVKITSS 78
C G+CR +C++ E YL C N Q CCL+ ++I+ S
Sbjct: 28 CMGNSGICRASCKKNEQPYLYCRNCQSCCLQSYMRISIS 66
>gi|83582798 beta-defensin 115 [Homo sapiens]
Length = 88
Score = 34.7 bits (78), Expect = 0.017
Identities = 18/66 (27%), Positives = 29/66 (43%), Gaps = 11/66 (16%)
Query: 4 MKPCLMTIAILMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNACREYEIQYLTCPN 63
+K ++ + +L++LAQ P G R C G CR +C+E E + C
Sbjct: 13 IKLSVLALVVLVVLAQTAPDGWIRR-----------CYYGTGRCRKSCKEIERKKEKCGE 61
Query: 64 DQKCCL 69
CC+
Sbjct: 62 KHICCV 67
>gi|21040279 defensin, beta 127 preproprotein [Homo sapiens]
Length = 99
Score = 34.3 bits (77), Expect = 0.022
Identities = 18/58 (31%), Positives = 24/58 (41%), Gaps = 2/58 (3%)
Query: 37 WNPCELYQGMCRNACREYEIQYLTCPNDQKCCLKLSVKITSSKNVKEDYDSNSNLSVT 94
WN QG CR CR E+ C N + CCL + K K + L++T
Sbjct: 25 WN--NYVQGHCRKICRVNEVPEALCENGRYCCLNIKELEACKKITKPPRPKPATLALT 80
>gi|239749357 PREDICTED: hypothetical protein XP_002347009 [Homo
sapiens]
Length = 111
Score = 33.1 bits (74), Expect = 0.048
Identities = 21/64 (32%), Positives = 28/64 (43%), Gaps = 3/64 (4%)
Query: 8 LMTIAILMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNACREYEIQYLTCPNDQKC 67
L TI+ +I + GK +E CE G C++ C E EI C N + C
Sbjct: 37 LSTISCALIKEDGNKEANSKITRGKFKEI---CERPNGSCQDFCLETEIHVGRCLNSRPC 93
Query: 68 CLKL 71
CL L
Sbjct: 94 CLPL 97
>gi|16905373 beta-defensin 118 [Homo sapiens]
Length = 123
Score = 33.1 bits (74), Expect = 0.048
Identities = 20/66 (30%), Positives = 35/66 (53%), Gaps = 10/66 (15%)
Query: 4 MKPCLMTIAILMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNACREYEIQYLTCPN 63
MK L+ + +L++L Q P +++G+ ++ WN G CR C++ E TC N
Sbjct: 1 MKLLLLALPMLVLLPQVIP-----AYSGE-KKCWNR----SGHCRKQCKDGEAVKDTCKN 50
Query: 64 DQKCCL 69
+ CC+
Sbjct: 51 LRACCI 56
>gi|82734223 beta-defensin 124 [Homo sapiens]
Length = 71
Score = 32.7 bits (73), Expect = 0.063
Identities = 19/66 (28%), Positives = 27/66 (40%), Gaps = 5/66 (7%)
Query: 9 MTIAILMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNACREYEIQYLTCPNDQKCC 68
MT +L ++A G H R + C QG C+ C E CP+ CC
Sbjct: 1 MTQLLLFLVALLVLG-----HVPSGRSEFKRCWKGQGACQTYCTRQETYMHLCPDASLCC 55
Query: 69 LKLSVK 74
L ++K
Sbjct: 56 LSYALK 61
>gi|62243658 PI-3-kinase-related kinase SMG-1 [Homo sapiens]
Length = 3661
Score = 32.3 bits (72), Expect = 0.082
Identities = 23/93 (24%), Positives = 39/93 (41%), Gaps = 6/93 (6%)
Query: 2 SVMKPCLMTIAILMILAQKTPGGLFRSHNGKSREPWNP---CELYQGMCRNACREYEIQY 58
SV++ CL + +A + P +F+ H + + W C C+ R+YE+QY
Sbjct: 2632 SVLRGCLEQLHHYATVALQYPKAIFQKHRIEQWKTWMEELICNTTVERCQELYRKYEMQY 2691
Query: 59 LTCPNDQKCCLKLSVKITSSKNVKEDYDSNSNL 91
P C + ++T + D NS L
Sbjct: 2692 APQPPPTVCQFITATEMTLQRYAA---DINSRL 2721
>gi|103485139 defensin, beta 104A precursor [Homo sapiens]
Length = 72
Score = 32.3 bits (72), Expect = 0.082
Identities = 21/67 (31%), Positives = 29/67 (43%), Gaps = 7/67 (10%)
Query: 4 MKPCLMTIAILMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNACREYEIQYLTCPN 63
M+ ++ +AI ++L Q P RS R C CR CR E + CPN
Sbjct: 1 MQRLVLLLAISLLLYQDLP---VRSEFELDRI----CGYGTARCRKKCRSQEYRIGRCPN 53
Query: 64 DQKCCLK 70
CCL+
Sbjct: 54 TYACCLR 60
>gi|103485137 defensin, beta 104B precursor [Homo sapiens]
Length = 72
Score = 32.3 bits (72), Expect = 0.082
Identities = 21/67 (31%), Positives = 29/67 (43%), Gaps = 7/67 (10%)
Query: 4 MKPCLMTIAILMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNACREYEIQYLTCPN 63
M+ ++ +AI ++L Q P RS R C CR CR E + CPN
Sbjct: 1 MQRLVLLLAISLLLYQDLP---VRSEFELDRI----CGYGTARCRKKCRSQEYRIGRCPN 53
Query: 64 DQKCCLK 70
CCL+
Sbjct: 54 TYACCLR 60
>gi|13624333 defensin, beta 126 preproprotein [Homo sapiens]
Length = 111
Score = 29.6 bits (65), Expect = 0.53
Identities = 18/70 (25%), Positives = 29/70 (41%), Gaps = 14/70 (20%)
Query: 4 MKPCLMTIAILMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNACREYEIQ----YL 59
MK L T+A+ M+LAQ G + C G+C+ C+ E+ +
Sbjct: 1 MKSLLFTLAVFMLLAQLVSGNWY----------VKKCLNDVGICKKKCKPEEMHVKNGWA 50
Query: 60 TCPNDQKCCL 69
C + CC+
Sbjct: 51 MCGKQRDCCV 60
>gi|76563936 defensin, beta 125 preproprotein [Homo sapiens]
Length = 156
Score = 28.9 bits (63), Expect = 0.91
Identities = 19/68 (27%), Positives = 27/68 (39%), Gaps = 9/68 (13%)
Query: 4 MKPCLMTIAILMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNACREYEIQYLTCPN 63
M ++T I +L + T G S EP + G CR C + E L C N
Sbjct: 1 MNILMLTFIICGLLTRVTKG---------SFEPQKCWKNNVGHCRRRCLDTERYILLCRN 51
Query: 64 DQKCCLKL 71
CC+ +
Sbjct: 52 KLSCCISI 59
>gi|74136827 beta-defensin 134 [Homo sapiens]
Length = 66
Score = 28.5 bits (62), Expect = 1.2
Identities = 20/67 (29%), Positives = 29/67 (43%), Gaps = 6/67 (8%)
Query: 4 MKPCLMTIAILMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNACREYEIQYLTCPN 63
MKP L+ + + + L G+ N S E C G+CR C E E+ C
Sbjct: 1 MKP-LLVVFVFLFLWDPVLAGI----NSLSSEMHKKC-YKNGICRLECYESEMLVAYCMF 54
Query: 64 DQKCCLK 70
+CC+K
Sbjct: 55 QLECCVK 61
>gi|83582796 beta-defensin 113 [Homo sapiens]
Length = 82
Score = 28.5 bits (62), Expect = 1.2
Identities = 11/29 (37%), Positives = 15/29 (51%), Gaps = 1/29 (3%)
Query: 40 CELYQGMCRNACREYEIQYLTCPNDQKCC 68
C+L +G C+ C +E Y C N CC
Sbjct: 35 CQLVRGACKPECNSWEYVYYYC-NVNPCC 62
>gi|82734214 beta-defensin 111 [Homo sapiens]
Length = 67
Score = 28.5 bits (62), Expect = 1.2
Identities = 12/32 (37%), Positives = 16/32 (50%), Gaps = 1/32 (3%)
Query: 40 CELYQGMCRNACREYEIQYLTCPN-DQKCCLK 70
C + G C+N C E EI+ C CCL+
Sbjct: 35 CRIGNGQCKNQCHENEIRIAYCIRPGTHCCLQ 66
>gi|46409558 beta-defensin 32 precursor [Homo sapiens]
Length = 95
Score = 28.1 bits (61), Expect = 1.6
Identities = 21/69 (30%), Positives = 25/69 (36%), Gaps = 9/69 (13%)
Query: 4 MKPCLMTIAILMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNACREYEIQYLTCPN 63
MK L+ +A L L Q P S G P G CR C E C
Sbjct: 1 MKFLLLVLAALGFLTQVIPA----SAGGSKCVSNTP-----GYCRTCCHWGETALFMCNA 51
Query: 64 DQKCCLKLS 72
+KCC+ S
Sbjct: 52 SRKCCISYS 60
>gi|22748611 defensin, beta 106A precursor [Homo sapiens]
Length = 65
Score = 27.3 bits (59), Expect = 2.7
Identities = 10/29 (34%), Positives = 13/29 (44%)
Query: 40 CELYQGMCRNACREYEIQYLTCPNDQKCC 68
C +G C+N C + E C KCC
Sbjct: 26 CNKLKGTCKNNCGKNEELIALCQKSLKCC 54
>gi|23503329 defensin, beta 119 isoform c precursor [Homo sapiens]
Length = 88
Score = 27.3 bits (59), Expect = 2.7
Identities = 9/25 (36%), Positives = 15/25 (60%)
Query: 45 GMCRNACREYEIQYLTCPNDQKCCL 69
G CR C++ E + C N ++CC+
Sbjct: 27 GHCRLLCKDGEDSIIRCRNRKRCCV 51
>gi|103485143 defensin, beta 106B precursor [Homo sapiens]
Length = 65
Score = 27.3 bits (59), Expect = 2.7
Identities = 10/29 (34%), Positives = 13/29 (44%)
Query: 40 CELYQGMCRNACREYEIQYLTCPNDQKCC 68
C +G C+N C + E C KCC
Sbjct: 26 CNKLKGTCKNNCGKNEELIALCQKSLKCC 54
>gi|169162343 PREDICTED: hypothetical protein [Homo sapiens]
Length = 189
Score = 26.9 bits (58), Expect = 3.5
Identities = 11/36 (30%), Positives = 18/36 (50%)
Query: 15 MILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNA 50
+ L Q+ PG R+ +S +P +P + G C A
Sbjct: 152 LALVQEAPGAAERAREARSEQPTSPGTRHVGCCSRA 187
>gi|113411617 PREDICTED: hypothetical protein [Homo sapiens]
Length = 189
Score = 26.9 bits (58), Expect = 3.5
Identities = 11/36 (30%), Positives = 18/36 (50%)
Query: 15 MILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNA 50
+ L Q+ PG R+ +S +P +P + G C A
Sbjct: 152 LALVQEAPGAAERAREARSEQPTSPGTRHVGCCSRA 187
>gi|82734217 beta-defensin 112 [Homo sapiens]
Length = 113
Score = 26.9 bits (58), Expect = 3.5
Identities = 12/35 (34%), Positives = 15/35 (42%), Gaps = 3/35 (8%)
Query: 37 WNPCELYQGMCRNAC--REYEIQYLTCPNDQKCCL 69
W C G C+N C E+ I Y P CC+
Sbjct: 51 WKSCTAIGGRCKNQCDDSEFRISYCARPTTH-CCV 84
>gi|32307109 WAP four-disulfide core domain 3 precursor [Homo
sapiens]
Length = 231
Score = 26.9 bits (58), Expect = 3.5
Identities = 17/66 (25%), Positives = 28/66 (42%), Gaps = 9/66 (13%)
Query: 3 VMKPCLMTIAILMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNACREYEIQYLTCP 62
+M CL + L+ L + + K E C ++ C+ C+ E+ CP
Sbjct: 1 MMLSCLFLLKALLALGS-LESWITAGEHAKEGE----CPPHKNPCKELCQGDEL----CP 51
Query: 63 NDQKCC 68
+QKCC
Sbjct: 52 AEQKCC 57
>gi|119395764 NLR family, pyrin domain containing 3 isoform a [Homo
sapiens]
Length = 1036
Score = 26.6 bits (57), Expect = 4.5
Identities = 13/50 (26%), Positives = 26/50 (52%)
Query: 42 LYQGMCRNACREYEIQYLTCPNDQKCCLKLSVKITSSKNVKEDYDSNSNL 91
L +G+ C+ ++ C CC LS +TSS+++++ N++L
Sbjct: 932 LCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDL 981
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.130 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,807,508
Number of Sequences: 37866
Number of extensions: 147805
Number of successful extensions: 421
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 6
Number of HSP's that attempted gapping in prelim test: 373
Number of HSP's gapped (non-prelim): 50
length of query: 102
length of database: 18,247,518
effective HSP length: 73
effective length of query: 29
effective length of database: 15,483,300
effective search space: 449015700
effective search space used: 449015700
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.