Guide to the Human Genome
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Name: SMG1 Sequence: fasta or formatted (3661aa) NCBI GI: 62243658
Description:

PI-3-kinase-related kinase SMG-1

Referenced in:

RNases and RNA Stability
Additional Serine / Threonine Protein Kinases

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.3        266           3
 C cysteine            2.0         72           2
 D aspartate           4.4        160           3
 E glutamate           7.2        265           3
 F phenylalanine       3.0        110           2
 G glycine             4.7        171           6
 H histidine           2.4         87           2
 I isoleucine          5.1        186           2
 K lysine              5.3        195           3
 L leucine            12.1        444           3
 M methionine          2.2         79           2
 N asparagine          3.9        144           3
 P proline             3.9        142           3
 Q glutamine           6.1        224           2
 R arginine            4.9        181           2
 S serine              8.6        314           4
 T threonine           6.2        228           3
 V valine              6.8        250           2
 W tryptophan          1.5         56           2
 Y tyrosine            2.4         87           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   PI-3-kinase-related kinase SMG-1 
LOC100288704          0.133   PREDICTED: hypothetical protein XP_002343506 
MTOR                  0.028   FK506 binding protein 12-rapamycin associated protein...
ATR                   0.022   ataxia telangiectasia and Rad3 related protein [Hom...
LOC648152             0.022   PREDICTED: similar to ataxia telangiectasia and Rad...
ATM                   0.021   ataxia telangiectasia mutated isoform 2 
ATM                   0.021   ataxia telangiectasia mutated isoform 1 
LOC651610             0.021   PREDICTED: similar to Serine-protein kinase ATM, pa...
PRKDC                 0.013   protein kinase, DNA-activated, catalytic polypeptide...
PRKDC                 0.010   protein kinase, DNA-activated, catalytic polypeptid...
LOC731751             0.010   PREDICTED: similar to protein kinase, DNA-activated...
TRRAP                 0.005   transformation/transcription domain-associated protei...
PIK3CB                0.005   catalytic phosphatidylinositol 3-kinase beta 
PIK3C3                0.004   catalytic phosphatidylinositol 3-kinase 3 
MYH3                  0.003   myosin, heavy chain 3, skeletal muscle, embryonic [H...
PIK3CG                0.003   phosphoinositide-3-kinase, catalytic, gamma polypept...
MYH6                  0.003   myosin heavy chain 6 
LOC651921             0.002   PREDICTED: similar to ataxia telangiectasia and Rad...
PIK3CD                0.002   catalytic phosphatidylinositol 3-kinase delta [Homo...
AKAP9                 0.002   A-kinase anchor protein 9 isoform 2 
CCDC88A               0.002   coiled-coil domain containing 88A isoform 2 
MYH7                  0.002   myosin, heavy chain 7, cardiac muscle, beta 
AKAP9                 0.002   A-kinase anchor protein 9 isoform 3 
TPR                   0.002   nuclear pore complex-associated protein TPR 
PIK3C2A               0.002   phosphoinositide-3-kinase, class 2 alpha polypeptid...
BICD1                 0.002   bicaudal D homolog 1 isoform 2 
BICD1                 0.002   bicaudal D homolog 1 isoform 1 
CCDC152               0.002   coiled-coil domain containing 152 
PIK3C2B               0.002   phosphoinositide-3-kinase, class 2 beta polypeptide...
GOLGA3                0.002   Golgi autoantigen, golgin subfamily a, 3 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
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