Guide to the Human Genome
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Name: NLRP3 Sequence: fasta or formatted (1036aa) NCBI GI: 119395764
Description:

NLR family, pyrin domain containing 3 isoform a

Referenced in:

Pyrin and Associated Functions

Other entries for this name:
alt prot [979aa] NLR family, pyrin domain containing 3 isoform d
alt prot [979aa] NLR family, pyrin domain containing 3 isoform c
alt prot [922aa] NLR family, pyrin domain containing 3 isoform b
alt mRNA [1036aa] NLR family, pyrin domain containing 3 isoform a
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.6         48           2
 C cysteine            4.3         45           2
 D aspartate           5.0         52           2
 E glutamate           7.9         82           6
 F phenylalanine       4.2         44           2
 G glycine             5.3         55           2
 H histidine           2.8         29           1
 I isoleucine          4.2         43           1
 K lysine              6.7         69           2
 L leucine            14.7        152           2
 M methionine          2.6         27           2
 N asparagine          3.5         36           2
 P proline             3.2         33           2
 Q glutamine           4.4         46           2
 R arginine            5.1         53           2
 S serine              8.3         86           3
 T threonine           4.1         42           3
 V valine              5.1         53           2
 W tryptophan          1.4         14           1
 Y tyrosine            2.6         27           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   NLR family, pyrin domain containing 3 isoform a [Ho... 
NLRP3                 1.000   NLR family, pyrin domain containing 3 isoform a [Hom...
NLRP3                 0.912   NLR family, pyrin domain containing 3 isoform d [Ho...
NLRP3                 0.861   NLR family, pyrin domain containing 3 isoform c [Ho...
NLRP3                 0.767   NLR family, pyrin domain containing 3 isoform b [Hom...
NLRP12                0.428   NLR family, pyrin domain containing 12 isoform 2 [Ho...
NLRP14                0.288   NLR family, pyrin domain containing 14 
NLRP4                 0.247   NLR family, pyrin domain containing 4 
NLRP9                 0.240   NLR family, pyrin domain containing 9 
NLRP2                 0.224   NLR family, pyrin domain containing 2 
NLRP13                0.221   NACHT, leucine rich repeat and PYD containing 13 [H...
NLRP1                 0.210   NLR family, pyrin domain containing 1 isoform 2 [Homo...
NLRP1                 0.210   NLR family, pyrin domain containing 1 isoform 5 [Hom...
NLRP1                 0.210   NLR family, pyrin domain containing 1 isoform 1 [Hom...
NLRP5                 0.210   NACHT, LRR and PYD containing protein 5 
NLRP1                 0.210   NLR family, pyrin domain containing 1 isoform 4 [Hom...
NLRP1                 0.210   NLR family, pyrin domain containing 1 isoform 3 [Hom...
NLRP7                 0.202   NACHT, leucine rich repeat and PYD containing 7 isof...
NLRP7                 0.198   NACHT, leucine rich repeat and PYD containing 7 isof...
NLRP8                 0.197   NLR family, pyrin domain containing 8 
NLRP7                 0.196   NACHT, leucine rich repeat and PYD containing 7 iso...
NLRP6                 0.183   NLR family, pyrin domain containing 6 
NLRP11                0.172   NLR family, pyrin domain containing 11 
NLRP10                0.159   NLR family, pyrin domain containing 10 
RNH1                  0.096   ribonuclease/angiogenin inhibitor 
RNH1                  0.096   ribonuclease/angiogenin inhibitor 
RNH1                  0.096   ribonuclease/angiogenin inhibitor 
RNH1                  0.096   ribonuclease/angiogenin inhibitor 
RNH1                  0.096   ribonuclease/angiogenin inhibitor 
RNH1                  0.096   ribonuclease/angiogenin inhibitor 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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