Guide to the Human Genome
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Search of human proteins with 7657441

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7657441 PDGFA associated protein 1 [Homo sapiens]
         (181 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7657441 PDGFA associated protein 1 [Homo sapiens]                  355   9e-99
gi|4758646 kinesin family member 3B [Homo sapiens]                     54   6e-08
gi|104526627 triadin [Homo sapiens]                                    54   1e-07
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]            53   1e-07
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            53   1e-07
gi|4506467 radixin [Homo sapiens]                                      50   1e-06
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]            49   2e-06
gi|148746195 trichohyalin [Homo sapiens]                               49   2e-06
gi|4557509 cylicin 2 [Homo sapiens]                                    48   5e-06
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ...    48   5e-06
gi|7657455 pescadillo homolog 1, containing BRCT domain [Homo sa...    48   5e-06
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap...    47   7e-06
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap...    47   7e-06
gi|14589862 aspartate beta-hydroxylase isoform d [Homo sapiens]        47   9e-06
gi|9910364 aspartate beta-hydroxylase isoform e [Homo sapiens]         47   9e-06
gi|148806928 hypothetical protein LOC57482 [Homo sapiens]              46   2e-05
gi|4505257 moesin [Homo sapiens]                                       45   3e-05
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    45   3e-05
gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens]        45   3e-05
gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens]        45   3e-05
gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens]        45   3e-05
gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens]        45   3e-05
gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo sapi...    45   4e-05
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            44   8e-05
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti...    44   8e-05
gi|151101404 prothymosin, alpha isoform 2 [Homo sapiens]               44   8e-05
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]           44   8e-05
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]           44   8e-05
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi...    44   1e-04
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]         44   1e-04

>gi|7657441 PDGFA associated protein 1 [Homo sapiens]
          Length = 181

 Score =  355 bits (912), Expect = 9e-99
 Identities = 181/181 (100%), Positives = 181/181 (100%)

Query: 1   MPKGGRKGGHKGRARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDS 60
           MPKGGRKGGHKGRARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDS
Sbjct: 1   MPKGGRKGGHKGRARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDS 60

Query: 61  DESEDEEDDYQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKA 120
           DESEDEEDDYQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKA
Sbjct: 61  DESEDEEDDYQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKA 120

Query: 121 KERYMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEERKAKDDATLSGKRMQSLSLN 180
           KERYMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEERKAKDDATLSGKRMQSLSLN
Sbjct: 121 KERYMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEERKAKDDATLSGKRMQSLSLN 180

Query: 181 K 181
           K
Sbjct: 181 K 181


>gi|4758646 kinesin family member 3B [Homo sapiens]
          Length = 747

 Score = 54.3 bits (129), Expect = 6e-08
 Identities = 50/178 (28%), Positives = 92/178 (51%), Gaps = 31/178 (17%)

Query: 21  EEIDAQLQAEKQKA-----REEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDY---QQ 72
           EEI A+L+A+ +K      +  E+++EGG    G  ++E++  + +E  D++DDY   QQ
Sbjct: 360 EEI-ARLKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYWREQQ 418

Query: 73  KRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYM--KMHLA 130
           ++  +E    +E+ + VA+   ++ + + +   E  RRE++  E   AK + M  K+ + 
Sbjct: 419 EKLEIEKRAIVEDHSLVAEEKMRLLK-EKEKKMEDLRREKDAAEMLGAKIKAMESKLLVG 477

Query: 131 GK------TEQAKADLARLAIIRKQREEAARKKEEER------KAKDDATLSGKRMQS 176
           GK       EQ K       I+ ++R+E A +K  ER      +++D+ TL  K   S
Sbjct: 478 GKNIVDHTNEQQK-------ILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYS 528


>gi|104526627 triadin [Homo sapiens]
          Length = 729

 Score = 53.5 bits (127), Expect = 1e-07
 Identities = 33/141 (23%), Positives = 70/141 (49%), Gaps = 14/141 (9%)

Query: 37  EEEQKEGGD-----GAAGDPKKEKKSLDSDESEDEEDD---------YQQKRKGVEGLID 82
           E+E+ + GD     G   +P   KK +  D++E +E           +++K KG E + +
Sbjct: 117 EDEEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVRE 176

Query: 83  IENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLAGKTEQAKADLAR 142
            E P + A   +K+ + +    K L++ +++    +K++E+  K    GK E+ K   A+
Sbjct: 177 KEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAK 236

Query: 143 LAIIRKQREEAARKKEEERKA 163
           +  ++K   +   K+++E+ A
Sbjct: 237 VKEVQKTPSKPKEKEDKEKAA 257



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 43/185 (23%), Positives = 84/185 (45%), Gaps = 41/185 (22%)

Query: 20  PEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRKGVEG 79
           P  +  +  +    A    E+KEG      + KK +K + S+  + E++D ++K +  E 
Sbjct: 291 PPPLPTEQASRPTPASPALEEKEG------EKKKAEKKVTSETKKKEKEDIKKKSEK-ET 343

Query: 80  LIDIEN--PNRVAQTTKKVTQL------DLDGPKELSRREREEIE-------KQKAKERY 124
            ID+E   P + ++T +   ++        D  KE S++ ++  E       KQ+ KE++
Sbjct: 344 AIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKH 403

Query: 125 MK--------------MHLAGKTEQAKADLARLAIIR----KQREEAARKKEEE-RKAKD 165
           ++                +  KTE+AK ++  ++I +    K+ E+  +  E+E RK K 
Sbjct: 404 VEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKS 463

Query: 166 DATLS 170
             T S
Sbjct: 464 GKTSS 468



 Score = 34.3 bits (77), Expect = 0.060
 Identities = 47/208 (22%), Positives = 88/208 (42%), Gaps = 42/208 (20%)

Query: 6   RKGGHKGRARQYTSPE-EIDAQL-QAEKQKAREEEEQKEGGDGAAGDPKK---------- 53
           +K  HK +  +   PE +I  ++   EK+K +E+  +KE  +  A   +K          
Sbjct: 140 KKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVREKEKPEKKATHKEKIEKKEKPETK 199

Query: 54  -----EKKSLDSDESEDEEDDYQQKRKGVEGLIDIENPNRVAQTTKKVTQLDL--DGPKE 106
                +KK+  +++SE      ++ +K V+G        +V QT  KV ++      PKE
Sbjct: 200 TLAKEQKKAKTAEKSE------EKTKKEVKG----GKQEKVKQTAAKVKEVQKTPSKPKE 249

Query: 107 LSRREREEIEKQKAKERY--------MKMHLAGKTEQAKADLARLAIIRKQREEAA---- 154
              +E+  + K + K++Y        + +H   K  Q+ A    L   +  R   A    
Sbjct: 250 KEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTPASPAL 309

Query: 155 -RKKEEERKAKDDATLSGKRMQSLSLNK 181
             K+ E++KA+   T   K+ +   + K
Sbjct: 310 EEKEGEKKKAEKKVTSETKKKEKEDIKK 337



 Score = 31.6 bits (70), Expect = 0.39
 Identities = 42/199 (21%), Positives = 81/199 (40%), Gaps = 29/199 (14%)

Query: 3   KGGRKGGHKGRARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDG----------AAGDPK 52
           +G +K   K    +    E+ D + ++EK+ A + E+++ G             A    K
Sbjct: 313 EGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAK 372

Query: 53  KEKKSLDSDESEDEEDDYQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGP-KELSRRE 111
           K++K  DS +++   +  Q K K  E       P   A++ KK   +  D   K  + R 
Sbjct: 373 KDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEP---AKSPKKEHSVPSDKQVKAKTERA 429

Query: 112 REEI---------------EKQKAKERYMKMHLAGKTEQAKADLARLAIIRKQREEAARK 156
           +EEI               +  K  E+ ++   +GKT     D   +    ++   + ++
Sbjct: 430 KEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKE 489

Query: 157 KEEERKAKDDATLSGKRMQ 175
           KE E K  +  + +GK ++
Sbjct: 490 KEPETKKDEKMSKAGKEVK 508



 Score = 28.1 bits (61), Expect = 4.3
 Identities = 37/180 (20%), Positives = 74/180 (41%), Gaps = 25/180 (13%)

Query: 2   PKGGRKGGHKGRARQYTSPEE-----IDAQLQAEKQKAREE------------EEQKEGG 44
           PKG ++   +       SP++      D Q++A+ ++A+EE            +++++  
Sbjct: 392 PKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTT 451

Query: 45  DGAAGDPKKEKKSLDSDESEDEEDDYQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGP 104
                + +KEK    S   +D+E    ++ K    L + E   +  +   K  +     P
Sbjct: 452 KTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAGKEVKPKP 511

Query: 105 KELSRREREEIEKQKAKERYMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEERKAK 164
            +L  ++ E+ E Q  KE   K  ++ K +  K D+       K  +  +  K EE+  K
Sbjct: 512 PQLQGKKEEKPEPQIKKE--AKPAISEKVQIHKQDIV------KPEKTVSHGKPEEKVLK 563



 Score = 27.3 bits (59), Expect = 7.3
 Identities = 39/182 (21%), Positives = 73/182 (40%), Gaps = 26/182 (14%)

Query: 1   MPKGGRKGGHKGRARQYTSPEEIDAQLQAEKQKAREEEEQKEGGD-----GAAGDPKKEK 55
           M K G++   K    Q    E+ + Q++ E + A  E+ Q    D           K E+
Sbjct: 500 MSKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEE 559

Query: 56  KSLDSDESEDEEDDYQQK-------RKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELS 108
           K L   ++   E   + K       R+     I  + P    + T +VT+         S
Sbjct: 560 KVLKQVKAVTIEKTAKPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVTE---------S 610

Query: 109 RREREEIEKQKAKERYMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEE-----RKA 163
            +++ EI ++++KE+    HL  +    + +  +L  + K  + A   K+ E     +KA
Sbjct: 611 GKKKTEISEKESKEKADMKHLREEKVSTRKESLQLHNVTKAEKPARVSKDVEDVPASKKA 670

Query: 164 KD 165
           K+
Sbjct: 671 KE 672


>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 290

 Score = 53.1 bits (126), Expect = 1e-07
 Identities = 36/158 (22%), Positives = 76/158 (48%), Gaps = 11/158 (6%)

Query: 11  KGRARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDY 70
           KGR R+     E +     EK++ R+ E+ ++G      + +++++     E E E D  
Sbjct: 131 KGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETERDRD 190

Query: 71  QQK--RKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMH 128
           +Q+   K  E   D E   +    T++  + D +G +E  RR   + ++ + KER  +  
Sbjct: 191 RQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRE-- 248

Query: 129 LAGKTEQAKADLARLAIIRKQREEAARKKEEERKAKDD 166
              + E+ K +       +K+R++  ++K++E K ++D
Sbjct: 249 -RDRKEERKKER------KKERKKERKEKKKEEKRRED 279



 Score = 39.7 bits (91), Expect = 0.001
 Identities = 43/184 (23%), Positives = 81/184 (44%), Gaps = 20/184 (10%)

Query: 4   GGRKGGHKGRARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDES 63
           G  +   + R R+ T  E  D   + ++++ R+E+E     D       +EK      ++
Sbjct: 74  GDDRQRERDRVREKTEKER-DRDRKRDRERRRKEKETNRNRD-------REK------QT 119

Query: 64  EDEEDDYQQKRKGVEGLID----IENPNRVAQTTKKVTQLDLDGPKEL-SRRERE-EIEK 117
           E E D  ++K+KG E   D     E      +  ++ T+ D DG +E  + RER+ E EK
Sbjct: 120 EIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREK 179

Query: 118 QKAKERYMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEERKAKDDATLSGKRMQSL 177
           QK +E          TE+ +         R+++ +  R++E +R+ + +     +R +  
Sbjct: 180 QKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRRERQRDR 239

Query: 178 SLNK 181
              K
Sbjct: 240 DRGK 243



 Score = 29.3 bits (64), Expect = 1.9
 Identities = 12/53 (22%), Positives = 30/53 (56%)

Query: 28  QAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRKGVEGL 80
           Q ++ + +E + +++  +    + KKE+K    ++ ++E+    +KRK  EG+
Sbjct: 236 QRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRKWGEGI 288


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 53.1 bits (126), Expect = 1e-07
 Identities = 41/174 (23%), Positives = 85/174 (48%), Gaps = 9/174 (5%)

Query: 6   RKGGHKGRA--RQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDES 63
           RK G K R   R+    E    + + EK++ RE  ++++ G+    + +++K+  + +  
Sbjct: 48  RKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENK 107

Query: 64  EDEEDDYQQKRKGVE-GLIDIENPNRVA-QTTKKVTQLDLDGPKELSRREREEIEKQKAK 121
           E EE + ++K++  E G    E   R   +  K+  + + +  KE   +ERE  E++K +
Sbjct: 108 EGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRE 167

Query: 122 ERYMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEERKAKDDATLSGKRMQ 175
            + +     G+ E+ + +  R    +++R    RKKE ERK + +     K+ +
Sbjct: 168 RKQV-----GEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKE 216



 Score = 48.9 bits (115), Expect = 2e-06
 Identities = 40/141 (28%), Positives = 69/141 (48%), Gaps = 16/141 (11%)

Query: 28  QAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRKGVEGLIDIENPN 87
           + E++K R E+E KEG +      KKEKK       E +E + +++RK  E         
Sbjct: 94  ERERKKRRREKENKEGEEKEKRK-KKEKKERGRTSKEGKERERKEERKREE--------- 143

Query: 88  RVAQTTKKVTQLDLDGPKELSRREREEI----EKQKAKERYMKMHLAGKTEQAKADLARL 143
           R  +  KK  +      KE  +RER+++    E++K KER  +       ++ K +  R 
Sbjct: 144 RKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERK 203

Query: 144 AIIRKQREEAARKKEEERKAK 164
              R++R++  +KKEE +K +
Sbjct: 204 E--RRERKKERKKKEERKKER 222



 Score = 48.1 bits (113), Expect = 4e-06
 Identities = 44/174 (25%), Positives = 79/174 (45%), Gaps = 21/174 (12%)

Query: 3   KGGRKGGHKGRARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDE 62
           K  +KG  K   R+           + E+++ R+++E+KE      G   KE K  +  E
Sbjct: 83  KKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKE-----RGRTSKEGKERERKE 137

Query: 63  SEDEEDDYQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIE---KQK 119
               E+  +++RK  E   + E   R  +  K+V + + +  KE  R+ER++ E   K++
Sbjct: 138 ERKREERKERERKKEEREKERERKERKKRERKQVGEKE-EERKEKERKERKKRERNRKER 196

Query: 120 AKERYMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEERKAKDDATLSGKR 173
            KER  K     K E            RK++EE  ++++++R+        GKR
Sbjct: 197 KKERERKERRERKKE------------RKKKEERKKERQKDRQTNWREKERGKR 238



 Score = 46.6 bits (109), Expect = 1e-05
 Identities = 35/136 (25%), Positives = 67/136 (49%), Gaps = 13/136 (9%)

Query: 31  KQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRKGVEGLIDIENPNRVA 90
           +++ RE E +KEG      + KKE++     E E  + + +++RK   G  + +   +  
Sbjct: 39  REREREIETRKEGKKERESERKKERR-----EREKRKREREKERKRERGKKEKKGERKKE 93

Query: 91  QTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLA--GKTEQAKADLARLAIIRK 148
           +  +K  +      +E   +E EE EK+K KE+  +   +  GK  + K +  R     +
Sbjct: 94  ERERKKRR------REKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKER 147

Query: 149 QREEAARKKEEERKAK 164
           +R++  R+KE ERK +
Sbjct: 148 ERKKEEREKERERKER 163



 Score = 34.3 bits (77), Expect = 0.060
 Identities = 23/88 (26%), Positives = 45/88 (51%), Gaps = 5/88 (5%)

Query: 93  TKKVTQLDLDGPKELSRREREEIEKQKAKERYM---KMHLAG--KTEQAKADLARLAIIR 147
           T+K  + + +  ++  RRERE+ ++++ KER     K    G  K E+ +    R     
Sbjct: 47  TRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKEN 106

Query: 148 KQREEAARKKEEERKAKDDATLSGKRMQ 175
           K+ EE  ++K++E+K +   +  GK  +
Sbjct: 107 KEGEEKEKRKKKEKKERGRTSKEGKERE 134



 Score = 34.3 bits (77), Expect = 0.060
 Identities = 24/106 (22%), Positives = 50/106 (47%), Gaps = 18/106 (16%)

Query: 30  EKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRKGVEGLIDIENPNRV 89
           E++K RE +E+K          K+E+K +   E E +E + ++++K           NR 
Sbjct: 153 EREKERERKERK----------KRERKQVGEKEEERKEKERKERKK--------RERNRK 194

Query: 90  AQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLAGKTEQ 135
            +  ++  +   +  KE  ++E  + E+QK ++   +    GK E+
Sbjct: 195 ERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRER 240


>gi|4506467 radixin [Homo sapiens]
          Length = 583

 Score = 50.1 bits (118), Expect = 1e-06
 Identities = 39/144 (27%), Positives = 73/144 (50%), Gaps = 12/144 (8%)

Query: 26  QLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDES--EDEEDDYQQKRKGVEGLIDI 83
           ++Q  K +AREE+ QK+       + KK+++  + ++   E E+++  ++ K +E    I
Sbjct: 301 EVQQMKAQAREEKHQKQLERAQLENEKKKREIAEKEKERIEREKEELMERLKQIEEQ-TI 359

Query: 84  ENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLAGKT-------EQA 136
           +    + + T+K   L+LD  ++ ++ E E +EK++      K  +A +        EQ 
Sbjct: 360 KAQKELEEQTRKA--LELDQERKRAKEEAERLEKERRAAEEAKSAIAKQAADQMKNQEQL 417

Query: 137 KADLARLAIIRKQREEAARKKEEE 160
            A+LA         EEA +KKEEE
Sbjct: 418 AAELAEFTAKIALLEEAKKKKEEE 441



 Score = 29.3 bits (64), Expect = 1.9
 Identities = 26/102 (25%), Positives = 49/102 (48%), Gaps = 10/102 (9%)

Query: 70  YQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHL 129
           Y ++RK     I+++     A+  K   QL+     E  +++RE  EK+K +    K  L
Sbjct: 291 YMRRRK--PDTIEVQQMKAQAREEKHQKQLER-AQLENEKKKREIAEKEKERIEREKEEL 347

Query: 130 AGKTEQAKADLARLAIIRKQREEAARK----KEEERKAKDDA 167
             + +Q +    +    +K+ EE  RK     +E ++AK++A
Sbjct: 348 MERLKQIEEQTIK---AQKELEEQTRKALELDQERKRAKEEA 386



 Score = 28.9 bits (63), Expect = 2.5
 Identities = 17/63 (26%), Positives = 32/63 (50%)

Query: 105 KELSRREREEIEKQKAKERYMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEERKAK 164
           KE   RE+EE+ ++  +     +    + E+       L   RK+ +E A + E+ER+A 
Sbjct: 337 KERIEREKEELMERLKQIEEQTIKAQKELEEQTRKALELDQERKRAKEEAERLEKERRAA 396

Query: 165 DDA 167
           ++A
Sbjct: 397 EEA 399


>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 202

 Score = 49.3 bits (116), Expect = 2e-06
 Identities = 37/162 (22%), Positives = 76/162 (46%), Gaps = 10/162 (6%)

Query: 6   RKGGHKGRARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEK-----KSLDS 60
           R+  H+ R R      + D + + E+QK R+ + Q+E       + ++E+     +   +
Sbjct: 33  RENRHRQRDRHRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKRQT 92

Query: 61  DESEDEEDDYQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKA 120
           D   D++ D ++KR   E   + E   +  +   K T+ + D  +E  R+   E ++Q+ 
Sbjct: 93  DRERDKDRDRERKR---ETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQRQRE 149

Query: 121 KERYMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEERK 162
           ++R          E+ +    R    +K+R+E  +KKEE+R+
Sbjct: 150 RKRETDRERQRWAEREERKKERKKERKKERKE--KKKEEKRR 189



 Score = 48.5 bits (114), Expect = 3e-06
 Identities = 40/164 (24%), Positives = 79/164 (48%), Gaps = 13/164 (7%)

Query: 10  HKGRARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDD 69
           H+ R RQ    +E + Q + ++Q+ RE E ++E         ++E+K   +D   D++ D
Sbjct: 43  HRERDRQTDREKERERQKERDRQRQRERETERETERQRERQRQRERKR-QTDRERDKDRD 101

Query: 70  YQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHL 129
            ++KR+        E   +  +   K T+ + D       RERE  ++Q+ +ER  +   
Sbjct: 102 RERKRETDRNR---ERNRKGGRERDKQTERERD-------RERER-QRQRERERQRQRER 150

Query: 130 AGKTEQAKADLARLAIIRKQREEAARKKEEERKAKDDATLSGKR 173
             +T++ +   A     +K+R++  RKKE + K K++     K+
Sbjct: 151 KRETDRERQRWAEREERKKERKK-ERKKERKEKKKEEKRREDKK 193



 Score = 32.0 bits (71), Expect = 0.30
 Identities = 23/88 (26%), Positives = 41/88 (46%), Gaps = 16/88 (18%)

Query: 6   RKGGHKGRARQYTSPEEIDAQLQAEKQKAREEEEQKEGG-------------DGAAGDPK 52
           RKGG   R R   +  E D + + ++Q+ RE + Q+E               +    + K
Sbjct: 116 RKGG---RERDKQTERERDRERERQRQRERERQRQRERKRETDRERQRWAEREERKKERK 172

Query: 53  KEKKSLDSDESEDEEDDYQQKRKGVEGL 80
           KE+K    ++ ++E+    +KRK  EG+
Sbjct: 173 KERKKERKEKKKEEKRREDKKRKWGEGI 200



 Score = 30.8 bits (68), Expect = 0.66
 Identities = 28/122 (22%), Positives = 53/122 (43%), Gaps = 20/122 (16%)

Query: 52  KKEKKSLDSDESEDEEDDYQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRRE 111
           ++ K+  D  +  + E D Q++R+               QT ++      D  +E  R+ 
Sbjct: 5   RERKRETDRGKETERERDRQREREN--------------QTERENRHRQRDRHRERDRQT 50

Query: 112 REEIEKQKAKERYMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEERKAKDDATLSG 171
             E E+++ KER  +     +TE+   +  R    ++QRE   RK++ +R+   D     
Sbjct: 51  DREKERERQKERDRQRQRERETER---ETERQRERQRQRE---RKRQTDRERDKDRDRER 104

Query: 172 KR 173
           KR
Sbjct: 105 KR 106


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 48.9 bits (115), Expect = 2e-06
 Identities = 46/197 (23%), Positives = 88/197 (44%), Gaps = 31/197 (15%)

Query: 11  KGRARQYTSP---EEIDAQLQAEKQKARE-----EEEQKEGGDGAAGDPKKEKKSLDSDE 62
           +GR R    P   E+ + QL+AE+++ RE     EEE+KE       + +KE + L+ +E
Sbjct: 779 RGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEE 838

Query: 63  SEDEEDDYQQKRKGVEGLIDIENPNRVAQT----------------------TKKVTQLD 100
                +  QQ ++  +GL + +   R  +                        K   Q  
Sbjct: 839 QLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQ 898

Query: 101 LDGPKELSRREREEIEKQKAKERYMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEE 160
           L   ++L + E EE+++++ ++R  +       E+ +       ++R++RE+  R++E E
Sbjct: 899 LRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREK-RRRQERE 957

Query: 161 RKAKDDATLSGKRMQSL 177
           R+ + D  L  K  Q L
Sbjct: 958 RQYRKDKKLQQKEEQLL 974



 Score = 48.9 bits (115), Expect = 2e-06
 Identities = 43/171 (25%), Positives = 84/171 (49%), Gaps = 27/171 (15%)

Query: 13   RARQYTSPEEIDAQLQAEKQKAREEEEQKE-------GGDGAAGDPKKEKKSLDSDESED 65
            R RQY   EE+  Q Q  KQ+ R+E+++ +         + A  D K   K  ++++   
Sbjct: 1195 RERQYREEEEL--QRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQ 1252

Query: 66   EEDDY---QQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKE 122
             ED     +Q ++ ++ L+  +      Q  ++  Q D   P+E  + EREE ++ K ++
Sbjct: 1253 LEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEE-EQLEREEQKEAKRRD 1311

Query: 123  RYMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEERKAKDDATLSGKR 173
            R        K+++ K       ++R++REE  R++E +RK +++  L  +R
Sbjct: 1312 R--------KSQEEKQ------LLREEREEKRRRQETDRKFREEEQLLQER 1348



 Score = 44.7 bits (104), Expect = 4e-05
 Identities = 33/151 (21%), Positives = 74/151 (49%), Gaps = 3/151 (1%)

Query: 16   QYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRK 75
            Q    E    +LQ  +++ REEEE ++  +   G+ ++ ++  + +    +E++ QQ+  
Sbjct: 1032 QLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEE- 1090

Query: 76   GVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLAGKTEQ 135
              E L+  E   R  Q  ++  + + +  +E  +  REE EK++ +E   +     + +Q
Sbjct: 1091 --EQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQ 1148

Query: 136  AKADLARLAIIRKQREEAARKKEEERKAKDD 166
             +  L R    +++R+E  R+  EE + + +
Sbjct: 1149 EEEQLLREEPEKRRRQELERQYREEEELQQE 1179



 Score = 43.1 bits (100), Expect = 1e-04
 Identities = 35/167 (20%), Positives = 80/167 (47%), Gaps = 16/167 (9%)

Query: 13   RARQYTSPEEIDAQ----LQAEKQKAREEE---------EQKEGGDGAAGDPKKEKKSLD 59
            R ++Y   EE+  +    L+ E++K R +E         E ++  +    + +++++  +
Sbjct: 986  REKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQE 1045

Query: 60   SDESEDEEDDYQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQK 119
             +    EE++ QQ+    E L+  E   R  Q  ++  + + +  +E  +  REE EK++
Sbjct: 1046 RERQYREEEELQQEE---EQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRR 1102

Query: 120  AKERYMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEERKAKDD 166
             +ER  +     + +Q +  L R    +++R+E  R+  EE + + +
Sbjct: 1103 RQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQE 1149



 Score = 42.7 bits (99), Expect = 2e-04
 Identities = 39/175 (22%), Positives = 78/175 (44%), Gaps = 25/175 (14%)

Query: 13   RARQYTSPEEIDAQ--------------LQAEKQKAREEEEQKEGGDGAAGDPKKEKKSL 58
            R RQY   EE+  +               + E+Q  +EEE Q+E       +P+K ++  
Sbjct: 1046 RERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQE 1105

Query: 59   DSDESEDEEDDYQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQ 118
               +  +EE+  Q++    E L+  E   R  Q  ++  + + +  +E  +  REE EK+
Sbjct: 1106 RERQCREEEELQQEE----EQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKR 1161

Query: 119  KAKERYMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEERKAKDDATLSGKR 173
            + +E   +     + +Q +  L R        E+  R++E ER+ +++  L  ++
Sbjct: 1162 RRQELERQYREEEELQQEEEQLLR-------EEQEKRRQERERQYREEEELQRQK 1209



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 40/163 (24%), Positives = 81/163 (49%), Gaps = 20/163 (12%)

Query: 17   YTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRKG 76
            Y  P  +  QL+ E+Q  +EEEE+ +       + +++++  + +    EE+  QQ+   
Sbjct: 890  YAKPA-LQEQLRKEQQLLQEEEEELQR------EEREKRRRQEQERQYREEEQLQQEE-- 940

Query: 77   VEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRRER----EEIEKQKAKERYMKMHLAGK 132
             E L+  E   R  Q  ++  + D    K+L ++E     EE EK++ +ER  K     +
Sbjct: 941  -EQLLREEREKRRRQERERQYRKD----KKLQQKEEQLLGEEPEKRRRQEREKKYREEEE 995

Query: 133  TEQAKADLARLAIIRKQREEAAR--KKEEERKAKDDATLSGKR 173
             +Q +  L R    +++R+E  R  +K++E + +++  L  +R
Sbjct: 996  LQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREER 1038



 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 40/156 (25%), Positives = 74/156 (47%), Gaps = 10/156 (6%)

Query: 21  EEIDAQLQA--EKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDE-----SEDEEDDYQQK 73
           EE+  Q Q   E+++ R EEEQ +   G   +   +++ L   E      +  E+  QQ+
Sbjct: 171 EELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQR 230

Query: 74  RKGVEGLIDIENPN--RVAQTTKKVTQLDLDGPKELSRREREEIEKQKAK-ERYMKMHLA 130
           R+  + +   E     R  +T  +  +  L   +   +RE +E E+Q  K ER       
Sbjct: 231 RERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRER 290

Query: 131 GKTEQAKADLARLAIIRKQREEAARKKEEERKAKDD 166
            + EQ +  L R   +R+++EE  R+++EER+ + +
Sbjct: 291 QEEEQQQQRLRREQQLRRKQEEERREQQEERREQQE 326



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 35/157 (22%), Positives = 77/157 (49%), Gaps = 3/157 (1%)

Query: 21   EEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRKGVEGL 80
            EE + + + E+++   EEEQ +  +      ++EK+     E +  +D   Q+++  E L
Sbjct: 916  EEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKE--EQL 973

Query: 81   IDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLAGKTEQAKADL 140
            +  E   R  Q  +K  + + +  +E  +  REE EK++ +E   +     + +Q +  L
Sbjct: 974  LGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQL 1033

Query: 141  ARLAIIRKQREEAARK-KEEERKAKDDATLSGKRMQS 176
             R    +++ +E  R+ +EEE   +++  L G+  ++
Sbjct: 1034 LREEREKRRLQERERQYREEEELQQEEEQLLGEERET 1070



 Score = 39.3 bits (90), Expect = 0.002
 Identities = 29/139 (20%), Positives = 69/139 (49%), Gaps = 4/139 (2%)

Query: 24  DAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRKGVEGLIDI 83
           + QL+ E+Q  RE++ ++E         ++E++     E E  E  ++Q+R+      + 
Sbjct: 392 EQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQ 451

Query: 84  ENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLAGKTEQAKADLARL 143
           E      +  ++  + + +  K+  +R++EE    + +ER++K+    + EQ +    +L
Sbjct: 452 EERRDWLKREEETERHEQERRKQQLKRDQEE----ERRERWLKLEEEERREQQERREQQL 507

Query: 144 AIIRKQREEAARKKEEERK 162
              +++R E   K++EE +
Sbjct: 508 RREQEERREQRLKRQEEEE 526



 Score = 38.9 bits (89), Expect = 0.002
 Identities = 34/149 (22%), Positives = 66/149 (44%), Gaps = 7/149 (4%)

Query: 21  EEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEE--DDYQQKRKGVE 78
           EE   Q +  + +  +EEE+KE         K+E+K  + +     E  ++ +Q RK   
Sbjct: 224 EEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLER 283

Query: 79  GLIDIENPNRVAQTTKKVTQLDLDGPKELSRRE-----REEIEKQKAKERYMKMHLAGKT 133
             +  E      Q  +   +  L   +E  RRE     RE+ E+++ +E   +  L  + 
Sbjct: 284 QELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQ 343

Query: 134 EQAKADLARLAIIRKQREEAARKKEEERK 162
           E+ +    R     ++RE+  R+++EE +
Sbjct: 344 EERREQQLRREQEEERREQQLRREQEEER 372



 Score = 38.9 bits (89), Expect = 0.002
 Identities = 38/154 (24%), Positives = 70/154 (45%), Gaps = 12/154 (7%)

Query: 11  KGRARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDY 70
           K + ++    E  +  L+ E+++ RE++E++E       + ++E++         EE++ 
Sbjct: 473 KQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRL-----KRQEEEER 527

Query: 71  QQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSR--REREEIEKQKAKERYMKMH 128
            Q+R   E  +  E   R  Q  K+  +  L+  +   R  RE+EE   Q  K    +  
Sbjct: 528 LQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQ 587

Query: 129 LAGKTEQAKADLARLAIIRKQREEAARKKEEERK 162
              K EQ +    RL     +REE  R ++EER+
Sbjct: 588 QRLKREQEERLEQRL-----KREEVERLEQEERR 616



 Score = 37.7 bits (86), Expect = 0.005
 Identities = 36/166 (21%), Positives = 80/166 (48%), Gaps = 11/166 (6%)

Query: 13   RARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQ 72
            +  Q    E    + Q  ++K REEEE ++  +    + +++++  + +    ++D+ QQ
Sbjct: 969  KEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQ 1028

Query: 73   KRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKE---LSRREREEIEKQKAKERYMKMHL 129
            +    E L+  E   R  Q  ++  + + +  +E   L   ERE   +Q+ + +Y K   
Sbjct: 1029 EE---EQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEE- 1084

Query: 130  AGKTEQAKADLARLAIIRKQREEAAR--KKEEERKAKDDATLSGKR 173
              + +Q +  L R    +++R+E  R  ++EEE + +++  L  +R
Sbjct: 1085 --ELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREER 1128



 Score = 37.4 bits (85), Expect = 0.007
 Identities = 31/147 (21%), Positives = 72/147 (48%), Gaps = 6/147 (4%)

Query: 21  EEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKS-LDSDESEDEEDDYQQKRKGVEG 79
           E  D QL+ E  + R ++ Q++  + A G+ + EK+  L+  + +  +++  ++R+  + 
Sbjct: 123 EPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQE 182

Query: 80  LIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEK----QKAKERYMKMHLAGKTEQ 135
             +        Q+ K     +    ++L RRE  E+ +    +K ++R  +     + E+
Sbjct: 183 REERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEE 242

Query: 136 AKADLARLAIIRKQREEAARKKEEERK 162
            K    R  ++RK+ EE  +++E +R+
Sbjct: 243 EKEWRKRETVLRKE-EEKLQEEEPQRQ 268



 Score = 37.4 bits (85), Expect = 0.007
 Identities = 29/144 (20%), Positives = 70/144 (48%), Gaps = 3/144 (2%)

Query: 22  EIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRK---GVE 78
           E+  + + EKQ+ R E + +   +    + +K +  L  +E + +E++ Q++R+     E
Sbjct: 217 ELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEE 276

Query: 79  GLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLAGKTEQAKA 138
            L  +E      +  ++  Q      ++  RR++EE  +++ +ER  +     + E+ + 
Sbjct: 277 QLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERRE 336

Query: 139 DLARLAIIRKQREEAARKKEEERK 162
              R     ++ ++  R++EEER+
Sbjct: 337 QQLRREQEERREQQLRREQEEERR 360



 Score = 37.4 bits (85), Expect = 0.007
 Identities = 35/166 (21%), Positives = 78/166 (46%), Gaps = 9/166 (5%)

Query: 6   RKGGHKGRARQYTSPEEIDAQLQAEKQKA----REEEEQKEGGDGAAGDPKKEKKSLDSD 61
           RK   + R +Q    E+ + + Q E+++     RE+EE++E       + ++ ++ L  +
Sbjct: 308 RKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRRE 367

Query: 62  ESEDEEDDYQQKRKGV--EGLIDIENPNRVAQTTKKVTQLDLDGP--KELSRREREEIEK 117
           + E+  +   ++ + +  E  +  E   R  Q  ++  QL  +    +E   R  +++ +
Sbjct: 368 QEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 427

Query: 118 QKAKERYMKMHLAGKTEQ-AKADLARLAIIRKQREEAARKKEEERK 162
           ++ +ER+ + H   + EQ  K +        K+ EE  R ++E RK
Sbjct: 428 EQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRK 473



 Score = 37.4 bits (85), Expect = 0.007
 Identities = 31/162 (19%), Positives = 72/162 (44%), Gaps = 4/162 (2%)

Query: 13   RARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQ 72
            R  Q    +E D +   E+Q+ R +E  ++  +      + E+K L   E E +    Q+
Sbjct: 1473 REEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFL---EEEQQLHRQQR 1529

Query: 73   KRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERY-MKMHLAG 131
            +RK ++    +    R  Q  +   +   +  +    RE +++ +Q+   ++ ++     
Sbjct: 1530 QRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVR 1589

Query: 132  KTEQAKADLARLAIIRKQREEAARKKEEERKAKDDATLSGKR 173
            + EQ +  +     +R+Q  +   ++E +RK ++D  L  +R
Sbjct: 1590 RQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQER 1631



 Score = 37.0 bits (84), Expect = 0.009
 Identities = 40/171 (23%), Positives = 76/171 (44%), Gaps = 20/171 (11%)

Query: 15   RQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDES----------- 63
            RQY   E    QLQ E+++   EE +K          +K+KK    +E            
Sbjct: 928  RQYREEE----QLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRR 983

Query: 64   EDEEDDYQQK---RKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKA 120
            ++ E  Y+++   ++  E L+  E   R  Q  ++  +   +  +E  +  REE EK++ 
Sbjct: 984  QEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRL 1043

Query: 121  KERYMKMHLAGKTEQAKADLARLAIIRKQREEAAR--KKEEERKAKDDATL 169
            +ER  +     + +Q +  L       ++R+E  R  +KEEE + +++  L
Sbjct: 1044 QERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLL 1094



 Score = 36.6 bits (83), Expect = 0.012
 Identities = 38/176 (21%), Positives = 77/176 (43%), Gaps = 30/176 (17%)

Query: 13   RARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQ 72
            R RQ    EE+    Q E+Q  REE E++   +        E++  + +E + EE+   +
Sbjct: 1106 RERQCREEEELQ---QEEEQLLREEREKRRRQE-------LERQYREEEEVQQEEEQLLR 1155

Query: 73   KRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRRER-------EEIEKQKAKERYM 125
            +        ++E   R  +  ++  +  L   +E  R+ER       EE+++QK K+RY 
Sbjct: 1156 EEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRY- 1214

Query: 126  KMHLAGKTEQAKADL------ARLAIIRKQREEAARKKEEERKAKDDATLSGKRMQ 175
                  + E  ++DL       +   +R  +     ++ E+ +  +D+ L  ++ Q
Sbjct: 1215 ------RDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQ 1264



 Score = 36.6 bits (83), Expect = 0.012
 Identities = 35/162 (21%), Positives = 74/162 (45%), Gaps = 25/162 (15%)

Query: 20   PEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRKGVEG 79
            PEE   + + +K+  R + + +E       + +++++  ++D    EE+   Q+R+    
Sbjct: 1294 PEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQERE---- 1349

Query: 80   LIDIENPNRVAQTTKKVTQLDL----------DGPKELSRRERE----EIEKQ---KAKE 122
                E P R  +  +K  + +L          +  + L R+ERE    + E+Q   + +E
Sbjct: 1350 ----EQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQERE 1405

Query: 123  RYMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEERKAK 164
            + ++     K  + +  L+R    RK REE  + + +ER+ K
Sbjct: 1406 QQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERK 1447



 Score = 35.8 bits (81), Expect = 0.021
 Identities = 29/150 (19%), Positives = 68/150 (45%), Gaps = 1/150 (0%)

Query: 13  RARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQ 72
           R ++    E ++ +L+ E ++ R E+E  E     A +  K +      + E E D  Q 
Sbjct: 658 RLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQS 717

Query: 73  KRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLAGK 132
           K        + +   +  +  ++  + +L   +E  R  R++ E+++ ++   +     K
Sbjct: 718 KVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEE-ERAHRQQQEEEQRRDFTWQWQAEEK 776

Query: 133 TEQAKADLARLAIIRKQREEAARKKEEERK 162
           +E+ +  L+    +R+QRE   R +E +++
Sbjct: 777 SERGRQRLSARPPLREQRERQLRAEERQQR 806



 Score = 35.0 bits (79), Expect = 0.035
 Identities = 34/159 (21%), Positives = 75/159 (47%), Gaps = 10/159 (6%)

Query: 15  RQYTSPEEIDAQLQAEKQKAREEEE-----QKEGGDGAAGDPKKEKKSLDSDESEDEEDD 69
           R+    E+   +L+ E+Q  R++EE     Q+E  +      ++E++       E EE  
Sbjct: 288 RERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERR 347

Query: 70  YQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHL 129
            QQ R+  E     +   R  +  ++  QL  +  ++L R ++   E+Q  +E+ ++   
Sbjct: 348 EQQLRREQEEERREQQLRREQEEERREQQLRRE--QQLRREQQLRREQQLRREQQLRREQ 405

Query: 130 AGKTEQ---AKADLARLAIIRKQREEAARKKEEERKAKD 165
             + EQ    +  L R   +R+++EE   +++ E++ ++
Sbjct: 406 QLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERRE 444



 Score = 34.7 bits (78), Expect = 0.046
 Identities = 31/160 (19%), Positives = 76/160 (47%), Gaps = 13/160 (8%)

Query: 13  RARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSL-DSDESEDEEDDYQ 71
           R +Q    +++  + Q  +++  E  EQK   +      K+E++   D  + E+E + ++
Sbjct: 409 REQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHE 468

Query: 72  QKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLAG 131
           Q+R+  +   D E   R     ++  +L+ +  +E   R  +++ +++ + R  ++    
Sbjct: 469 QERRKQQLKRDQEEERR-----ERWLKLEEEERREQQERREQQLRREQEERREQRLKRQE 523

Query: 132 KTEQAKADLARLAIIRKQREEAAR-----KKEEERKAKDD 166
           + E+ +  L     +R  RE+  R     K+EEE++ + +
Sbjct: 524 EEERLQQRLRSEQQLR--REQEERREQLLKREEEKRLEQE 561



 Score = 34.3 bits (77), Expect = 0.060
 Identities = 37/186 (19%), Positives = 80/186 (43%), Gaps = 34/186 (18%)

Query: 13  RARQYTSPEEIDAQLQAEKQKAREEEEQKEG------GDGAAGDPKKEKKSLDSDESED- 65
           R ++    E +  +L++E+Q  RE+EE++E             + ++++   + +E  D 
Sbjct: 518 RLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQ 577

Query: 66  ----EEDDYQQKRKG-----VEGLIDIENPNRVAQTTKKVTQLDLDGPKELSR------- 109
               EE+  QQ+ K      +E  +  E   R+ Q  ++  +L  + P+E  R       
Sbjct: 578 LLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSE 637

Query: 110 -----------REREEIEKQKAKERYMKMHLAGKTEQAKADLARLAIIRKQREEAARKKE 158
                      RE++E  +Q+ K    +  L  + ++   +  R   + ++ +E AR++ 
Sbjct: 638 EQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERI 697

Query: 159 EERKAK 164
           + R  K
Sbjct: 698 KSRIPK 703



 Score = 33.5 bits (75), Expect = 0.10
 Identities = 30/155 (19%), Positives = 70/155 (45%), Gaps = 9/155 (5%)

Query: 10   HKGRARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDD 69
            H+ + R++   E+   + + E++  +EE++ +          ++++   D D    EE+ 
Sbjct: 1369 HQEQGRKFLEEEQRLRRQERERKFLKEEQQLR-------CQEREQQLRQDRDRKFREEEQ 1421

Query: 70   YQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSR--REREEIEKQKAKERYMKM 127
               +++      + E   R  +  +K  + +    +E  R  RE E++ +++ +++  + 
Sbjct: 1422 QLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQ 1481

Query: 128  HLAGKTEQAKADLARLAIIRKQREEAARKKEEERK 162
                K  + +  L R    RK RE+  R +E ERK
Sbjct: 1482 ERDRKFLEEEQQLRRQERDRKFREQELRSQEPERK 1516



 Score = 33.5 bits (75), Expect = 0.10
 Identities = 34/152 (22%), Positives = 71/152 (46%), Gaps = 10/152 (6%)

Query: 13   RARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQ 72
            R  Q  S +E D + + E+QK R +E++++  +    D ++ ++     +   E D   +
Sbjct: 1567 REEQQLSRQERDRKFRLEEQKVRRQEQERKFME----DEQQLRRQEGQQQLRQERD---R 1619

Query: 73   KRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLAGK 132
            K +  E L+      ++ +  +   +  L+   +L R+ERE+ + +  ++R  +      
Sbjct: 1620 KFREDEQLLQEREEQQLHRQERD--RKFLEEEPQLRRQEREQ-QLRHDRDRKFREEEQLL 1676

Query: 133  TEQAKADLARLAIIRKQREEAARKKEEERKAK 164
             E  +  L R    RK REE  + + +ER+ K
Sbjct: 1677 QEGEEQQLRRQERDRKFREEEQQLRRQERERK 1708



 Score = 31.2 bits (69), Expect = 0.51
 Identities = 27/141 (19%), Positives = 68/141 (48%), Gaps = 8/141 (5%)

Query: 21  EEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRKGVEGL 80
           E  + + + ++ K  +EEE++E       + ++E++     +   E+++ +++R     L
Sbjct: 465 ERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQR-----L 519

Query: 81  IDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLAGKTEQAKADL 140
              E   R+ Q  +   QL  +  +   +  + E EK+  +ER  +  L  + E+ +  L
Sbjct: 520 KRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER-REQRLKREQEERRDQL 578

Query: 141 ARLAIIRKQREEAARKKEEER 161
            +     ++R++  ++++EER
Sbjct: 579 LKRE--EERRQQRLKREQEER 597



 Score = 30.4 bits (67), Expect = 0.87
 Identities = 34/162 (20%), Positives = 67/162 (41%), Gaps = 13/162 (8%)

Query: 7    KGGHKGRARQYTSPEEIDAQLQ-------AEKQKAREEEEQKEGGDGAAGDPKKEKKSLD 59
            KG    + RQ    +  D Q Q        E+Q+   E+E++         P++E+   +
Sbjct: 1243 KGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLERE 1302

Query: 60   SDESEDEEDDYQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQK 119
              +     D   Q+ K +    + E   R  +T +K  + +    + L  RE + + +Q+
Sbjct: 1303 EQKEAKRRDRKSQEEKQLLRE-EREEKRRRQETDRKFREEE----QLLQEREEQPLRRQE 1357

Query: 120  AKERYMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEER 161
               ++ +  L  + EQ +  L     +R+Q  E    KEE++
Sbjct: 1358 RDRKFREEELRHQ-EQGRKFLEEEQRLRRQERERKFLKEEQQ 1398



 Score = 28.9 bits (63), Expect = 2.5
 Identities = 25/147 (17%), Positives = 67/147 (45%), Gaps = 1/147 (0%)

Query: 13   RARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQ 72
            R R++   E+   + + E++   EE+ ++E         ++ +K L+ ++   E ++ Q 
Sbjct: 1705 RERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQL 1764

Query: 73   KRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLAGK 132
            +R+  +     E   R  +  +++   + D       + R+E E+Q+ + +        +
Sbjct: 1765 RRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWE 1824

Query: 133  TEQAKADLARLAIIRKQREEAARKKEE 159
             EQ + +  +   +R++R+   R +E+
Sbjct: 1825 EEQLQLE-EQEQRLRQERDRQYRAEEQ 1850


>gi|4557509 cylicin 2 [Homo sapiens]
          Length = 348

 Score = 47.8 bits (112), Expect = 5e-06
 Identities = 51/203 (25%), Positives = 88/203 (43%), Gaps = 36/203 (17%)

Query: 3   KGGRKGGHKGRARQYTSPEEIDAQLQAEKQKAREEE------EQKEGGDGAAGDPKKEKK 56
           K G+K   KG+  +    E++DA+  ++K K   E+      E ++   GA  D KK+KK
Sbjct: 135 KQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKK 194

Query: 57  SLDSDESEDEEDDYQQKRKGVE-----GLIDIENPNRVA---QTTKKVTQLDLDGPKELS 108
             DS++ +D   + + ++ G E     G  D +     A   Q  K   + D DG K+ +
Sbjct: 195 --DSNKGKDSATESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDAN 252

Query: 109 RREREEIEKQKAKERYMKMHLAGK------------------TEQAKADLARLAIIRKQR 150
           + +  +  K+ AKE  +K     K                   + A  D  ++A    ++
Sbjct: 253 KGDESKDAKKDAKE--IKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEK 310

Query: 151 EEAARKKEEERKAKDDATLSGKR 173
           E A  KK+ ++ AK DA    K+
Sbjct: 311 ESADSKKDAKKNAKKDAKKDAKK 333


>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
           sapiens]
          Length = 600

 Score = 47.8 bits (112), Expect = 5e-06
 Identities = 37/164 (22%), Positives = 71/164 (43%), Gaps = 13/164 (7%)

Query: 10  HKGRARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDD 69
           H  R R+     E + + + ++Q  RE + Q++         ++E+ S    E E E D 
Sbjct: 205 HSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERAS----ERETERDK 260

Query: 70  YQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHL 129
            +++ +  +   D     R  QT +K  Q   +  +E  R+   + E+++ +ER  K   
Sbjct: 261 ERERERDRDRDRDRRQKERERQTDRK-RQRRTERDRETERKRERQRERERERERNRKRER 319

Query: 130 AGKTEQAKADLARLAIIRKQREEAARKKEEERKAKDDATLSGKR 173
             + E+ +         R++  E  R+KE ERK K    +  +R
Sbjct: 320 ERERERERE--------RQRETERDREKERERKRKRQTEMDRER 355



 Score = 44.7 bits (104), Expect = 4e-05
 Identities = 37/170 (21%), Positives = 71/170 (41%), Gaps = 8/170 (4%)

Query: 9   GHKGRARQYTSPEEIDAQLQAEKQKAR----EEEEQKEGGDGAAGDPKKEKKSLDSDESE 64
           G +GR RQ     E + Q  AEK++ R    E + Q E       + +K ++     E +
Sbjct: 135 GERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQ 194

Query: 65  DEEDDYQQKRKGVEGL-IDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKER 123
            E+++  + R    G   + E         K+ T  + D  ++  R   ++ E+++A ER
Sbjct: 195 REKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASER 254

Query: 124 YMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEERKAKDDATLSGKR 173
             +     K  + + D  R    R++  E    ++ +R+ + D     KR
Sbjct: 255 ETE---RDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKR 301



 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 38/156 (24%), Positives = 65/156 (41%), Gaps = 29/156 (18%)

Query: 11  KGRARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDY 70
           K R RQ     +   + +  +QK RE E ++EG  G         +  D     + + D 
Sbjct: 103 KERERQTDRERDRQREKERNRQKERERETEREGERG-------RDRQTDGQRERERQRDA 155

Query: 71  QQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLA 130
           +++R   E   D E   +  +  +K      +  +E +R+ER E E+Q+ KE        
Sbjct: 156 EKER---ERQTDRERQRQTERNRQK------EREREKNRQERRERERQREKE-------- 198

Query: 131 GKTEQAKADLARLAIIRKQREEAARKKEEERKAKDD 166
            KTE   ++       R++  E   + E ERK + D
Sbjct: 199 NKTEDRHSERG-----RERERERETETETERKRQTD 229



 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 30/151 (19%), Positives = 67/151 (44%), Gaps = 4/151 (2%)

Query: 13  RARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQ 72
           R RQ     E + Q + E+++ RE+E + E      G  ++ ++  +++     + D ++
Sbjct: 173 RNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRER 232

Query: 73  KRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSR-REREEIEKQKAKERYMKMHLAG 131
            R   +   + E   +  +      + + D  +E  R R+R+   +QK +ER        
Sbjct: 233 DR---QRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQR 289

Query: 132 KTEQAKADLARLAIIRKQREEAARKKEEERK 162
           +TE+ +    +    R++  E  R ++ ER+
Sbjct: 290 RTERDRETERKRERQRERERERERNRKRERE 320



 Score = 40.0 bits (92), Expect = 0.001
 Identities = 30/148 (20%), Positives = 65/148 (43%), Gaps = 4/148 (2%)

Query: 28  QAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRKGVEGLIDIENPN 87
           Q E++  R+ E ++E       D  +E++     E E + D  + +++  E     E   
Sbjct: 70  QTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERER 129

Query: 88  RVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLAGKTEQAKADLARLAIIR 147
              +  ++      DG +E  R+   E E+++  +R  +     +TE+ +         R
Sbjct: 130 ETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQR----QTERNRQKEREREKNR 185

Query: 148 KQREEAARKKEEERKAKDDATLSGKRMQ 175
           ++R E  R++E+E K +D  +  G+  +
Sbjct: 186 QERRERERQREKENKTEDRHSERGRERE 213



 Score = 38.5 bits (88), Expect = 0.003
 Identities = 29/142 (20%), Positives = 65/142 (45%), Gaps = 22/142 (15%)

Query: 22  EIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESE-DEEDDYQQKRKGVEGL 80
           E D + + ++++ RE E ++E       + ++E++     E+E D E + ++KRK     
Sbjct: 292 ERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRK----- 346

Query: 81  IDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLAGKTEQAKADL 140
                         + T++D +  ++  R  R + E+++ +ER      A + E+ + D 
Sbjct: 347 --------------RQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDR 392

Query: 141 ARLAIIRKQREEAARKKEEERK 162
            R    +K+RE    K  + ++
Sbjct: 393 DRDR--QKERERQTEKDRDGQR 412



 Score = 35.0 bits (79), Expect = 0.035
 Identities = 27/113 (23%), Positives = 53/113 (46%), Gaps = 7/113 (6%)

Query: 13  RARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEK-KSLDSDESEDEEDDYQ 71
           + R+  + ++ D Q + EKQ+ RE++ + E G     + +K+K +  D +   D +   Q
Sbjct: 398 KERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQ 457

Query: 72  QKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERY 124
           +KR      + +  P R A++   V Q D + P    R +    + + A  R+
Sbjct: 458 RKR----STLYVNPPPRTARS--GVVQSDPNRPTRGIRWKSSPEDPKAASTRF 504



 Score = 33.5 bits (75), Expect = 0.10
 Identities = 28/118 (23%), Positives = 49/118 (41%), Gaps = 30/118 (25%)

Query: 6   RKGGHKGRARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESED 65
           R+ G +GR +   +  E + + + ++Q ARE EE+              ++  D D  ++
Sbjct: 357 RQTGREGRRQ---AERERERERERDRQSAREREER--------------ERDRDRDRQKE 399

Query: 66  EEDDYQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKER 123
            E   ++ R G              + T+K  + + D   E  R    E EKQK +ER
Sbjct: 400 RERQTEKDRDG-------------QRETEKQREREKDRESERGRERGREREKQKGRER 444


>gi|7657455 pescadillo homolog 1, containing BRCT domain [Homo
           sapiens]
          Length = 588

 Score = 47.8 bits (112), Expect = 5e-06
 Identities = 39/161 (24%), Positives = 74/161 (45%), Gaps = 18/161 (11%)

Query: 6   RKGGHKGRARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESED 65
           ++G   G   +    EE D   + +  +  E EE++E  D  AG  K+E+  L + E + 
Sbjct: 446 QRGEDPGNLNESEEEEEEDDNNEGDGDEEGENEEEEE--DAEAGSEKEEEARLAALEEQR 503

Query: 66  EEDDYQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYM 125
            E    +K + + G + +E+  R+AQ             +E S  +R  I   K +E+Y+
Sbjct: 504 MEG---KKPRVMAGTLKLEDKQRLAQ-------------EEESEAKRLAIMMMKKREKYL 547

Query: 126 KMHLAGKTEQAKADLARLAIIRKQREEAARKKEEERKAKDD 166
              +     +   +  +LA  RK  +EA R +++ +KA+ +
Sbjct: 548 YQKIMFGKRRKIREANKLAEKRKAHDEAVRSEKKAKKARPE 588


>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
          Length = 1758

 Score = 47.4 bits (111), Expect = 7e-06
 Identities = 50/196 (25%), Positives = 82/196 (41%), Gaps = 22/196 (11%)

Query: 8    GGHKGRARQYTS--PEEI---DAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDE 62
            GG   R+R   S  PE++   D   Q +  K++E+E +   GDG     KK +K    +E
Sbjct: 851  GGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEE 910

Query: 63   SED--EEDDYQQKRKGVEGLIDIEN--------PNRVAQTTKKVTQLDLDGP--KELSRR 110
            SE     +  +  RK  E     EN        P+R   T  +   +D +    K +S +
Sbjct: 911  SEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEK 970

Query: 111  EREEIEKQKAKERYMKMHLAGKTEQAKADLARLA-----IIRKQREEAARKKEEERKAKD 165
            ++ E +K KAK    K    G     K ++ + A      +  +RE + R +   +KAK+
Sbjct: 971  DKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKE 1030

Query: 166  DATLSGKRMQSLSLNK 181
            +   +     S S  K
Sbjct: 1031 ETPKTDNTKSSSSSQK 1046



 Score = 28.1 bits (61), Expect = 4.3
 Identities = 20/85 (23%), Positives = 37/85 (43%), Gaps = 9/85 (10%)

Query: 2    PKGGRKGGHKGRARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPK--------- 52
            P G +   H   A    S +    + + EK+K ++ ++ K+    A  + +         
Sbjct: 1672 PSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKH 1731

Query: 53   KEKKSLDSDESEDEEDDYQQKRKGV 77
            K+KKS  + + E E++   QK K V
Sbjct: 1732 KKKKSKKNKDKEKEKEKDDQKVKSV 1756


>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
          Length = 1792

 Score = 47.4 bits (111), Expect = 7e-06
 Identities = 50/196 (25%), Positives = 82/196 (41%), Gaps = 22/196 (11%)

Query: 8    GGHKGRARQYTS--PEEI---DAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDE 62
            GG   R+R   S  PE++   D   Q +  K++E+E +   GDG     KK +K    +E
Sbjct: 885  GGQSHRSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEE 944

Query: 63   SED--EEDDYQQKRKGVEGLIDIEN--------PNRVAQTTKKVTQLDLDGP--KELSRR 110
            SE     +  +  RK  E     EN        P+R   T  +   +D +    K +S +
Sbjct: 945  SEGFLNPELLETSRKSREPTGVEENKTDSLFVLPSRDDATPVRDEPMDAESITFKSVSEK 1004

Query: 111  EREEIEKQKAKERYMKMHLAGKTEQAKADLARLA-----IIRKQREEAARKKEEERKAKD 165
            ++ E +K KAK    K    G     K ++ + A      +  +RE + R +   +KAK+
Sbjct: 1005 DKRERDKPKAKGDKTKRKNDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPPIKKAKE 1064

Query: 166  DATLSGKRMQSLSLNK 181
            +   +     S S  K
Sbjct: 1065 ETPKTDNTKSSSSSQK 1080



 Score = 28.1 bits (61), Expect = 4.3
 Identities = 20/85 (23%), Positives = 37/85 (43%), Gaps = 9/85 (10%)

Query: 2    PKGGRKGGHKGRARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPK--------- 52
            P G +   H   A    S +    + + EK+K ++ ++ K+    A  + +         
Sbjct: 1706 PSGSQTRSHSSSASSAESQDSKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKH 1765

Query: 53   KEKKSLDSDESEDEEDDYQQKRKGV 77
            K+KKS  + + E E++   QK K V
Sbjct: 1766 KKKKSKKNKDKEKEKEKDDQKVKSV 1790


>gi|14589862 aspartate beta-hydroxylase isoform d [Homo sapiens]
          Length = 210

 Score = 47.0 bits (110), Expect = 9e-06
 Identities = 30/123 (24%), Positives = 63/123 (51%), Gaps = 6/123 (4%)

Query: 2   PKGGRKGGHKGRARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSD 61
           P G  K   K + ++ T  E    + + EK ++R+E + +E   G   D +K+KK  D+D
Sbjct: 81  PSGVAKRKTKAKVKELTKEE---LKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADAD 137

Query: 62  ESEDEEDDYQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAK 121
            S  E    ++ R+  +  +D+E   +  +  KK T +  D   +++ R++++ ++ ++ 
Sbjct: 138 LSRKESPKGKKDRE--KEKVDLEKSAKTKENRKKSTNMK-DVSSKMASRDKDDRKESRSS 194

Query: 122 ERY 124
            RY
Sbjct: 195 TRY 197



 Score = 27.7 bits (60), Expect = 5.6
 Identities = 29/134 (21%), Positives = 62/134 (46%), Gaps = 29/134 (21%)

Query: 31  KQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRKGVEGLIDIENPNRVA 90
           K KA+ +E  KE       + KKEK+  +S +    E+  + K++ V             
Sbjct: 88  KTKAKVKELTKE-------ELKKEKEKPESRKESKNEERKKGKKEDV------------- 127

Query: 91  QTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLAGKTEQAKADLARLAIIRKQR 150
           +  KK+   DL      SR+E  + +K + KE+ + +  + KT++ +     +  +  + 
Sbjct: 128 RKDKKIADADL------SRKESPKGKKDREKEK-VDLEKSAKTKENRKKSTNMKDVSSKM 180

Query: 151 EEAARKKEEERKAK 164
             A+R K++ ++++
Sbjct: 181 --ASRDKDDRKESR 192


>gi|9910364 aspartate beta-hydroxylase isoform e [Homo sapiens]
          Length = 225

 Score = 47.0 bits (110), Expect = 9e-06
 Identities = 30/123 (24%), Positives = 63/123 (51%), Gaps = 6/123 (4%)

Query: 2   PKGGRKGGHKGRARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSD 61
           P G  K   K + ++ T  E    + + EK ++R+E + +E   G   D +K+KK  D+D
Sbjct: 96  PSGVAKRKTKAKVKELTKEE---LKKEKEKPESRKESKNEERKKGKKEDVRKDKKIADAD 152

Query: 62  ESEDEEDDYQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAK 121
            S  E    ++ R+  +  +D+E   +  +  KK T +  D   +++ R++++ ++ ++ 
Sbjct: 153 LSRKESPKGKKDRE--KEKVDLEKSAKTKENRKKSTNMK-DVSSKMASRDKDDRKESRSS 209

Query: 122 ERY 124
            RY
Sbjct: 210 TRY 212



 Score = 27.7 bits (60), Expect = 5.6
 Identities = 29/134 (21%), Positives = 62/134 (46%), Gaps = 29/134 (21%)

Query: 31  KQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRKGVEGLIDIENPNRVA 90
           K KA+ +E  KE       + KKEK+  +S +    E+  + K++ V             
Sbjct: 103 KTKAKVKELTKE-------ELKKEKEKPESRKESKNEERKKGKKEDV------------- 142

Query: 91  QTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLAGKTEQAKADLARLAIIRKQR 150
           +  KK+   DL      SR+E  + +K + KE+ + +  + KT++ +     +  +  + 
Sbjct: 143 RKDKKIADADL------SRKESPKGKKDREKEK-VDLEKSAKTKENRKKSTNMKDVSSKM 195

Query: 151 EEAARKKEEERKAK 164
             A+R K++ ++++
Sbjct: 196 --ASRDKDDRKESR 207


>gi|148806928 hypothetical protein LOC57482 [Homo sapiens]
          Length = 1233

 Score = 46.2 bits (108), Expect = 2e-05
 Identities = 45/171 (26%), Positives = 83/171 (48%), Gaps = 13/171 (7%)

Query: 7   KGGHKGRARQYTSPEEIDAQLQAEKQKAREEEEQKE-------GGDGAAGDPKKEKKSLD 59
           + GH G  +  T  EE    L +E+++ R+E+  +E           AA   + E++ L 
Sbjct: 196 QNGHPGEDKP-TWHEEEPNPLDSEEERRRQEDYWRELEAKCKRQKAEAAEKRRLEEQRLQ 254

Query: 60  SDESEDEEDDYQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGP--KELSRREREEIEK 117
           + E    E++ +Q+    EG    E P    +  ++  Q  L+ P  ++  RREREE E+
Sbjct: 255 ALERRLWEENRRQELLEEEGEGQ-EPPLEAERAPREEQQRSLEAPGWEDAERREREERER 313

Query: 118 QKAKERYMKMHLAGKTEQAK--ADLARLAIIRKQREEAARKKEEERKAKDD 166
            +A+E   ++    + E+ +   + ARL   R+Q EE  R  EE ++ +++
Sbjct: 314 LEAEEERRRLQAQAQAEERRRLEEDARLEERRRQEEEEGRCAEELKRQEEE 364



 Score = 30.8 bits (68), Expect = 0.66
 Identities = 33/155 (21%), Positives = 68/155 (43%), Gaps = 19/155 (12%)

Query: 23  IDAQLQAEKQKAREEE---EQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRKGVEG 79
           + AQ QAE+++  EE+   E++   +   G   +E K  + +E+E  E+  QQ+      
Sbjct: 323 LQAQAQAEERRRLEEDARLEERRRQEEEEGRCAEELKRQEEEEAEGWEELEQQE------ 376

Query: 80  LIDIENPNRVAQTT----KKVTQLDLDGPKELSRREREEIEKQKAK-----ERYMKMHLA 130
             +++ P    + T    +   + DL   +E  +   E+   Q ++     E  ++    
Sbjct: 377 -AEVQGPPEALEETGEGRRGAEEEDLGEEEEEGQAHLEDWRGQLSELLNDFEERLEDQER 435

Query: 131 GKTEQAKADLARLAIIRKQREEAARKKEEERKAKD 165
            K E  +       I  +Q  EA R++E++ ++ D
Sbjct: 436 LKPEGQREHSEEPGICEEQNPEAERRREQQGRSGD 470


>gi|4505257 moesin [Homo sapiens]
          Length = 577

 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 38/145 (26%), Positives = 71/145 (48%), Gaps = 14/145 (9%)

Query: 26  QLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRKGVEGLIDIEN 85
           ++Q  K +AREE+ QK+       + KK+++  + ++ + E    ++K + +E L  IE 
Sbjct: 301 EVQQMKAQAREEKHQKQMERAMLENEKKKREMAEKEKEKIE----REKEELMERLKQIEE 356

Query: 86  PNRVAQ-----TTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLAGK-----TEQ 135
             + AQ      T++  +L+ +  +  S  E+   E+Q+A+E    +  A +      EQ
Sbjct: 357 QTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQ 416

Query: 136 AKADLARLAIIRKQREEAARKKEEE 160
              ++A L     Q E A +KKE E
Sbjct: 417 LALEMAELTARISQLEMARQKKESE 441



 Score = 28.1 bits (61), Expect = 4.3
 Identities = 24/107 (22%), Positives = 48/107 (44%), Gaps = 4/107 (3%)

Query: 70  YQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHL 129
           Y ++RK     I+++     A+  K   Q++     E  +++RE  EK+K K    K  L
Sbjct: 291 YMRRRK--PDTIEVQQMKAQAREEKHQKQMER-AMLENEKKKREMAEKEKEKIEREKEEL 347

Query: 130 AGKTEQAKADLARL-AIIRKQREEAARKKEEERKAKDDATLSGKRMQ 175
             + +Q +    +    + +Q   A   ++E ++A+ +A    K  Q
Sbjct: 348 MERLKQIEEQTKKAQQELEEQTRRALELEQERKRAQSEAEKLAKERQ 394


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 45.4 bits (106), Expect = 3e-05
 Identities = 39/160 (24%), Positives = 76/160 (47%), Gaps = 7/160 (4%)

Query: 25  AQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDS---DESEDEEDDYQQKRKGVEGLI 81
           AQ +AEK   +E E +K   + A     KEK+ L++   D+S+ +E   + + + V+  +
Sbjct: 229 AQKKAEK---KERERKKRDEEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKV 285

Query: 82  DIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLAGKTEQAKADLA 141
            ++     A   K  T    +   E  ++++++ +K+  KE   K    G ++ A     
Sbjct: 286 TVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSK-ATVKAM 344

Query: 142 RLAIIRKQREEAARKKEEERKAKDDATLSGKRMQSLSLNK 181
           + A+ + + EE  +K+EEE + K    L  KR +   L +
Sbjct: 345 QEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQ 384



 Score = 42.4 bits (98), Expect = 2e-04
 Identities = 39/166 (23%), Positives = 73/166 (43%), Gaps = 21/166 (12%)

Query: 11  KGRARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLD------SDESE 64
           K +   Y+  ++ D   +  K+   + ++  +  DG+  D    KK  +      S ES 
Sbjct: 128 KPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESG 187

Query: 65  DEEDDYQQKRKGVEGL------IDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQ 118
           DE D++ Q RKG +         +IE+ N     + K+  +     K+  ++ERE  ++ 
Sbjct: 188 DESDEFLQSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTV---AQKKAEKKERERKKRD 244

Query: 119 KAKERYMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEERKAK 164
           + K +  K+    + E  K D +      KQ+E   + +EE  K+K
Sbjct: 245 EEKAKLRKLKEKEELETGKKDQS------KQKESQRKFEEETVKSK 284



 Score = 38.5 bits (88), Expect = 0.003
 Identities = 38/169 (22%), Positives = 77/169 (45%), Gaps = 25/169 (14%)

Query: 5   GRKGGHKGRARQYTSPEE-IDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDES 63
           G+K   K +  Q    EE + +++  +       EE+ E    A  D + +KK  D  + 
Sbjct: 262 GKKDQSKQKESQRKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGDKKKKDKKKK 321

Query: 64  EDEEDDYQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKER 123
           + E+++ ++++K        + P++    T K  Q  L   KE    ER++ E+++  +R
Sbjct: 322 KGEKEEKEKEKK--------KGPSK---ATVKAMQEALAKLKE--EEERQKREEEERIKR 368

Query: 124 YMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEERKAKDDATLSGK 172
             ++    K E+           R ++E+  RKK++E++ K+     GK
Sbjct: 369 LEELEAKRKEEE-----------RLEQEKRERKKQKEKERKERLKKEGK 406



 Score = 37.4 bits (85), Expect = 0.007
 Identities = 32/153 (20%), Positives = 65/153 (42%), Gaps = 22/153 (14%)

Query: 28  QAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRKGVEGLIDIENPN 87
           Q  K+++ ++ + +E  D  +   K  K  ++     D++DD+ +  K  +G        
Sbjct: 101 QKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKG-------- 152

Query: 88  RVAQTTKKV--TQLDLDGPKELSRRER------------EEIEKQKAKERYMKMHLAGKT 133
           +  ++ KK   ++ D D  K++  R R            E ++ +K +++  K       
Sbjct: 153 KAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKKNQKNKPGPNI 212

Query: 134 EQAKADLARLAIIRKQREEAARKKEEERKAKDD 166
           E    D      I+   ++ A KKE ERK +D+
Sbjct: 213 ESGNEDDDASFKIKTVAQKKAEKKERERKKRDE 245



 Score = 36.6 bits (83), Expect = 0.012
 Identities = 32/119 (26%), Positives = 51/119 (42%), Gaps = 13/119 (10%)

Query: 24  DAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRKGVEGLID- 82
           DA L   +  A +EE +K  G+    + K+  +  + +E E+EED+  ++ +  EG  + 
Sbjct: 500 DAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEG 559

Query: 83  ---IENPNRVAQTTKKVTQLDLDGPKELSR---------REREEIEKQKAKERYMKMHL 129
               E   +V+        LD    KE+S          R +EE    KAK R  K  L
Sbjct: 560 SEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEKRRL 618



 Score = 34.7 bits (78), Expect = 0.046
 Identities = 22/88 (25%), Positives = 40/88 (45%), Gaps = 18/88 (20%)

Query: 9   GHKGRARQYTSPEEIDAQLQAEKQKAREEEEQKEGG--DGAAGDPKKEK----------- 55
           G+K       +PEE + + + E++    EEE++E G  +G+ GD + EK           
Sbjct: 520 GNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTL 579

Query: 56  -----KSLDSDESEDEEDDYQQKRKGVE 78
                K + SD   D +DD  ++ +  +
Sbjct: 580 DKKPSKEMSSDSEYDSDDDRTKEERAYD 607



 Score = 30.4 bits (67), Expect = 0.87
 Identities = 35/150 (23%), Positives = 65/150 (43%), Gaps = 26/150 (17%)

Query: 30  EKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRKGVEGLIDIENPNRV 89
           E  K ++++++K+G      + +KEKK   S  +     +   K K  E     E   R+
Sbjct: 310 EGDKKKKDKKKKKG---EKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERI 366

Query: 90  AQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLAGKTEQAKADLARLAIIRKQ 149
               K++ +L+    KE  R E+E+ E++K KE+  K  L                  K+
Sbjct: 367 ----KRLEELEAK-RKEEERLEQEKRERKKQKEKERKERL------------------KK 403

Query: 150 REEAARKKEEERKAKDDATLSGKRMQSLSL 179
             +   K + E +A+ +ATL   + Q + +
Sbjct: 404 EGKLLTKSQREARARAEATLKLLQAQGVEV 433



 Score = 27.3 bits (59), Expect = 7.3
 Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 13/98 (13%)

Query: 34  AREEEEQKEGGDGAAGDPKKEKKSLDSDESE--DEEDDYQQKRKGVEG-----LIDIENP 86
           A+E+E QK     + G  KKEKK  D DE +   E ++   + +G++       +     
Sbjct: 32  AKEQEPQK-----SKGKKKKEKKKQDFDEDDILKELEELSLEAQGIKADRETVAVKPTEN 86

Query: 87  NRVAQTTKKVTQLDLDGPKE-LSRREREEIEKQKAKER 123
           N    T+K   +    G K+     + EE+E + +K +
Sbjct: 87  NEEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSK 124


>gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens]
          Length = 282

 Score = 45.1 bits (105), Expect = 3e-05
 Identities = 46/164 (28%), Positives = 70/164 (42%), Gaps = 38/164 (23%)

Query: 22  EIDAQLQAEKQKAR-----EEEEQKEGGDGAAGDPKKEKKSLDS--------DESEDEED 68
           E DA+ +AE ++ R     EEEE KE  DG   + K + +S           D    + D
Sbjct: 24  EEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFD 83

Query: 69  DYQQKR-----KGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKER 123
           D  +KR       ++ LI+    NR  +  + V+  D    +   R E++ I  ++ KER
Sbjct: 84  DIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKER 143

Query: 124 YMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEERKAKDDA 167
                             RLA  R +REE    +E  RKA+D+A
Sbjct: 144 QN----------------RLAEERARREE----EENRRKAEDEA 167



 Score = 30.4 bits (67), Expect = 0.87
 Identities = 20/94 (21%), Positives = 47/94 (50%), Gaps = 11/94 (11%)

Query: 28  QAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRKGVEGLIDIENPN 87
           +AE+Q+ R E E++     A     +E+   + +E+  + +D  +K+K +  ++      
Sbjct: 129 RAEQQRIRNEREKERQNRLA-----EERARREEEENRRKAEDEARKKKALSNMMHFGGYI 183

Query: 88  RVAQTTKKVTQLDLDGPKELSRREREEIEKQKAK 121
           + AQT +K       G ++  R ++++I  ++ K
Sbjct: 184 QKAQTERK------SGKRQTEREKKKKILAERRK 211


>gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens]
          Length = 285

 Score = 45.1 bits (105), Expect = 3e-05
 Identities = 46/164 (28%), Positives = 70/164 (42%), Gaps = 38/164 (23%)

Query: 22  EIDAQLQAEKQKAR-----EEEEQKEGGDGAAGDPKKEKKSLDS--------DESEDEED 68
           E DA+ +AE ++ R     EEEE KE  DG   + K + +S           D    + D
Sbjct: 29  EEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFD 88

Query: 69  DYQQKR-----KGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKER 123
           D  +KR       ++ LI+    NR  +  + V+  D    +   R E++ I  ++ KER
Sbjct: 89  DIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKER 148

Query: 124 YMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEERKAKDDA 167
                             RLA  R +REE    +E  RKA+D+A
Sbjct: 149 QN----------------RLAEERARREE----EENRRKAEDEA 172


>gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens]
          Length = 288

 Score = 45.1 bits (105), Expect = 3e-05
 Identities = 46/164 (28%), Positives = 70/164 (42%), Gaps = 38/164 (23%)

Query: 22  EIDAQLQAEKQKAR-----EEEEQKEGGDGAAGDPKKEKKSLDS--------DESEDEED 68
           E DA+ +AE ++ R     EEEE KE  DG   + K + +S           D    + D
Sbjct: 29  EEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFD 88

Query: 69  DYQQKR-----KGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKER 123
           D  +KR       ++ LI+    NR  +  + V+  D    +   R E++ I  ++ KER
Sbjct: 89  DIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKER 148

Query: 124 YMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEERKAKDDA 167
                             RLA  R +REE    +E  RKA+D+A
Sbjct: 149 QN----------------RLAEERARREE----EENRRKAEDEA 172


>gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens]
          Length = 295

 Score = 45.1 bits (105), Expect = 3e-05
 Identities = 46/164 (28%), Positives = 70/164 (42%), Gaps = 38/164 (23%)

Query: 22  EIDAQLQAEKQKAR-----EEEEQKEGGDGAAGDPKKEKKSLDS--------DESEDEED 68
           E DA+ +AE ++ R     EEEE KE  DG   + K + +S           D    + D
Sbjct: 39  EEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFD 98

Query: 69  DYQQKR-----KGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKER 123
           D  +KR       ++ LI+    NR  +  + V+  D    +   R E++ I  ++ KER
Sbjct: 99  DIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKER 158

Query: 124 YMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEERKAKDDA 167
                             RLA  R +REE    +E  RKA+D+A
Sbjct: 159 QN----------------RLAEERARREE----EENRRKAEDEA 182


>gi|41327771 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 [Homo
           sapiens]
          Length = 820

 Score = 44.7 bits (104), Expect = 4e-05
 Identities = 44/189 (23%), Positives = 83/189 (43%), Gaps = 27/189 (14%)

Query: 6   RKGGHKGRARQYTSPEEIDA---QLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSL---- 58
           R+GG + R+R  +   E +    + + +K++ R ++++    DG   D  +++ SL    
Sbjct: 53  RRGGSRSRSRSRSKSAERERRHKERERDKERDRNKKDRDRDKDGHRRDKDRKRSSLSPGR 112

Query: 59  --------DSDESEDEEDDYQQKRK-----GVEGLIDIENPNRVAQTTKKVTQLDLDGPK 105
                   D D  +DEED++  K+       +E L+  +     A+   K         +
Sbjct: 113 GKDFKSRKDRDSKKDEEDEHGDKKPKAQPLSLEELLAKKKAEEEAEAKPKFLSKAEREAE 172

Query: 106 ELSRREREEIEKQKAKERYMKMHLAGKTEQAKADLARLAIIRKQ-REEAARKKEEERKAK 164
            L RR++E  E+Q+  E   K     K +Q + DL R  +   Q RE   R++  ER+  
Sbjct: 173 ALKRRQQEVEERQRMLEEERK-----KRKQFQ-DLGRKMLEDPQERERRERRERMERETN 226

Query: 165 DDATLSGKR 173
            +    G++
Sbjct: 227 GNEDEEGRQ 235


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 43.9 bits (102), Expect = 8e-05
 Identities = 36/162 (22%), Positives = 78/162 (48%), Gaps = 8/162 (4%)

Query: 5   GRKGGHKGRARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESE 64
           G+K   K + R+     E   + + E++K R+E  +KE         K+E+K     E +
Sbjct: 59  GKKEKKKRKKRERGKERE---RKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERK 115

Query: 65  DEEDDYQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERY 124
            +++  +++R+  +         R  +  K+  +    G +E  R++R++ E++K +ER 
Sbjct: 116 KKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERN 175

Query: 125 MKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEERKAKDD 166
            K     K E+ + +  R    +++++E  +KKE ++  K D
Sbjct: 176 RKER---KKERERKE--RRERKKERKKERRKKKERKKDRKTD 212



 Score = 41.6 bits (96), Expect = 4e-04
 Identities = 32/153 (20%), Positives = 70/153 (45%), Gaps = 10/153 (6%)

Query: 13  RARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQ 72
           R ++    E+   + + E+++ R ++E+K+      G  ++ K+     + ++  +  ++
Sbjct: 36  RKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERR 95

Query: 73  KRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLAGK 132
           KRK  +   + +   R  +  KK         KE  R  ++  E+++ K R  K     K
Sbjct: 96  KRKKEKKKRERKQRGRRERKKKKER-------KERERENKQRRERKRKKRRKKKRRKERK 148

Query: 133 TEQAKADLARLAIIRKQREEAARKKEEERKAKD 165
            E+ +    R    RK+R++  R+K+ ER  K+
Sbjct: 149 REKERGKRERK---RKKRKKEEREKKRERNRKE 178



 Score = 40.8 bits (94), Expect = 6e-04
 Identities = 33/160 (20%), Positives = 72/160 (45%), Gaps = 19/160 (11%)

Query: 3   KGGRKGGHKGRARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDE 62
           K   +G  + R R+             E++K R+E  +KE         K+E+K     E
Sbjct: 67  KKRERGKERERKRK-------------EREKQRKERREKERRKRKKEKKKRERKQRGRRE 113

Query: 63  SEDEEDDYQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKE 122
            + +++  +++R+  +         R  +  K+  +    G +E  R++R++ E++K +E
Sbjct: 114 RKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRE 173

Query: 123 RYMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEERK 162
           R  K     +  + + +       +K+R++  RKK+E +K
Sbjct: 174 RNRKERKKERERKERRER------KKERKKERRKKKERKK 207


>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
           [Homo sapiens]
          Length = 213

 Score = 43.9 bits (102), Expect = 8e-05
 Identities = 38/164 (23%), Positives = 75/164 (45%), Gaps = 10/164 (6%)

Query: 11  KGRARQYTSPEEIDAQLQAEKQKAREEEEQKE---GGDGAAGDPKKEKKSLDSD-ESEDE 66
           + R R      E D   + EKQ  RE E Q+E     D      ++  K  ++D  +E +
Sbjct: 46  RDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETD 105

Query: 67  EDDYQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKE-LSRREREEIEKQKAKERYM 125
            +  +QK + +E + D E   +     ++ T  + D  +E  + RERE   ++K ++R+ 
Sbjct: 106 RERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHR 165

Query: 126 KMHLAGKTE-----QAKADLARLAIIRKQREEAARKKEEERKAK 164
           +     K E     + K       + R+++ E  RK++ +R+++
Sbjct: 166 ERERERKRERERKRETKERERHTDMERERQRETDRKRDRQRESE 209



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 29/141 (20%), Positives = 60/141 (42%), Gaps = 7/141 (4%)

Query: 22  EIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRKGVEGLI 81
           E D Q   E+ + R+ + ++E      G+ ++E++     + E E +  +++        
Sbjct: 45  ERDRQRDRERNRERDRDREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTET 104

Query: 82  DIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLAGKTEQAKADLA 141
           D E   +  +  ++V   + +  KE+ R  + + E  + +ER  +       E+   D  
Sbjct: 105 DRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTED-- 162

Query: 142 RLAIIRKQREEAARKKEEERK 162
                R +  E  RK+E ERK
Sbjct: 163 -----RHRERERERKRERERK 178



 Score = 40.8 bits (94), Expect = 6e-04
 Identities = 33/148 (22%), Positives = 63/148 (42%), Gaps = 7/148 (4%)

Query: 17  YTSPEEIDAQLQAEKQKAREEEEQKEGG--DGAAGDPKKEKKSLDSDESEDEEDDYQQKR 74
           +T  E +D Q +  ++  RE +  KE    D  +   ++  +  + +   D E + Q  R
Sbjct: 11  HTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRDRERNRERDRDREREKQTDR 70

Query: 75  KGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLAGKTE 134
           +G     + +      +  ++ T+ + D  +E  R    + E+QK KER M+     + E
Sbjct: 71  EG-----ERQRERERDRDRQRETERERDKERETDRHTETDRERQKQKEREMERVRDRERE 125

Query: 135 QAKADLARLAIIRKQREEAARKKEEERK 162
           + K         R+   E  R+ E ER+
Sbjct: 126 KQKEMGRERQTDRETDRERERQAERERE 153


>gi|151101404 prothymosin, alpha isoform 2 [Homo sapiens]
          Length = 110

 Score = 43.9 bits (102), Expect = 8e-05
 Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 4/77 (5%)

Query: 3   KGGRKGGHKGRARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAA--GDPKKEKKSLDS 60
           + GR     G A +    +E D ++  E+++  EEEE++E GDG    GD  +E +S   
Sbjct: 28  ENGRDAPANGNANEENGEQEADNEVDEEEEEGGEEEEEEEEGDGEEEDGDEDEEAESATG 87

Query: 61  DES--EDEEDDYQQKRK 75
             +  +DE+DD   K++
Sbjct: 88  KRAAEDDEDDDVDTKKQ 104


>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
          Length = 709

 Score = 43.9 bits (102), Expect = 8e-05
 Identities = 35/150 (23%), Positives = 65/150 (43%), Gaps = 19/150 (12%)

Query: 22  EIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRKGVEGLI 81
           E+D +     Q ++EE   +E G         + ++  S  S+++ ++ + + +GVE   
Sbjct: 158 EVDRRASRSSQSSKEEVNSEEYGS--------DHETGSSGSSDEQGNNTENEEEGVEE-- 207

Query: 82  DIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLAGKTEQAKADLA 141
           D+E    V +  ++  ++D DG +E    E EE E+++ +E Y         EQ + D  
Sbjct: 208 DVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEY---------EQDERDQK 258

Query: 142 RLAIIRKQREEAARKKEEERKAKDDATLSG 171
                   R EA+    E     D +  SG
Sbjct: 259 EEGNDYDTRSEASDSGSESVSFTDGSVRSG 288



 Score = 33.9 bits (76), Expect = 0.078
 Identities = 16/56 (28%), Positives = 33/56 (58%), Gaps = 1/56 (1%)

Query: 21  EEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRKG 76
           E+++   + E+  A E+EE  E G+    + ++E++  + +E E E+D+  QK +G
Sbjct: 207 EDVEEDEEVEED-AEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEG 261



 Score = 33.1 bits (74), Expect = 0.13
 Identities = 14/58 (24%), Positives = 33/58 (56%)

Query: 18  TSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRK 75
           T  EE   +   E+ +  EE+ +++      G+ ++E++  + +E E+EE++Y+Q  +
Sbjct: 198 TENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDER 255



 Score = 28.5 bits (62), Expect = 3.3
 Identities = 14/53 (26%), Positives = 29/53 (54%), Gaps = 8/53 (15%)

Query: 21  EEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQK 73
           EE+D   + E+++  EEEE++E         ++E+   D  + ++E +DY  +
Sbjct: 223 EEVDEDGEEEEEEEEEEEEEEE--------EEEEEYEQDERDQKEEGNDYDTR 267


>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
          Length = 727

 Score = 43.9 bits (102), Expect = 8e-05
 Identities = 35/150 (23%), Positives = 65/150 (43%), Gaps = 19/150 (12%)

Query: 22  EIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRKGVEGLI 81
           E+D +     Q ++EE   +E G         + ++  S  S+++ ++ + + +GVE   
Sbjct: 158 EVDRRASRSSQSSKEEVNSEEYGS--------DHETGSSGSSDEQGNNTENEEEGVEE-- 207

Query: 82  DIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLAGKTEQAKADLA 141
           D+E    V +  ++  ++D DG +E    E EE E+++ +E Y         EQ + D  
Sbjct: 208 DVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEY---------EQDERDQK 258

Query: 142 RLAIIRKQREEAARKKEEERKAKDDATLSG 171
                   R EA+    E     D +  SG
Sbjct: 259 EEGNDYDTRSEASDSGSESVSFTDGSVRSG 288



 Score = 33.9 bits (76), Expect = 0.078
 Identities = 16/56 (28%), Positives = 33/56 (58%), Gaps = 1/56 (1%)

Query: 21  EEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRKG 76
           E+++   + E+  A E+EE  E G+    + ++E++  + +E E E+D+  QK +G
Sbjct: 207 EDVEEDEEVEED-AEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEG 261



 Score = 33.1 bits (74), Expect = 0.13
 Identities = 14/58 (24%), Positives = 33/58 (56%)

Query: 18  TSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRK 75
           T  EE   +   E+ +  EE+ +++      G+ ++E++  + +E E+EE++Y+Q  +
Sbjct: 198 TENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDER 255



 Score = 28.5 bits (62), Expect = 3.3
 Identities = 14/53 (26%), Positives = 29/53 (54%), Gaps = 8/53 (15%)

Query: 21  EEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQK 73
           EE+D   + E+++  EEEE++E         ++E+   D  + ++E +DY  +
Sbjct: 223 EEVDEDGEEEEEEEEEEEEEEE--------EEEEEYEQDERDQKEEGNDYDTR 267


>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 123

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 26/113 (23%), Positives = 57/113 (50%)

Query: 52  KKEKKSLDSDESEDEEDDYQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRRE 111
           KK+KK  +++E+E+ E+  +++ K  +     +   +  +  KK  + +    KE   ++
Sbjct: 2   KKKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKK 61

Query: 112 REEIEKQKAKERYMKMHLAGKTEQAKADLARLAIIRKQREEAARKKEEERKAK 164
           R+   K+K +E   +     + E+ + +       RK++++  RK+EEE K K
Sbjct: 62  RKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKK 114



 Score = 42.0 bits (97), Expect = 3e-04
 Identities = 37/138 (26%), Positives = 60/138 (43%), Gaps = 29/138 (21%)

Query: 28  QAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQ-QKRKGVEGLIDIENP 86
           + E+ +  EEEE+KEG        +KEK+     E E ++   + +KRK  E     E  
Sbjct: 12  ETEETEETEEEEEKEG-------KRKEKRKEKRKEKEKKKKTKETEKRKEKEE----EEK 60

Query: 87  NRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLAGKTEQAKADLARLAII 146
            R  +  KK  + + +  +E    E+EE EK++ + R  K                    
Sbjct: 61  KRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKR----------------- 103

Query: 147 RKQREEAARKKEEERKAK 164
           R++ EE  +KK+  RK K
Sbjct: 104 RRKEEEEEKKKKRRRKTK 121



 Score = 37.0 bits (84), Expect = 0.009
 Identities = 29/120 (24%), Positives = 54/120 (45%), Gaps = 23/120 (19%)

Query: 7   KGGHKGRARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDE 66
           K G +   R+    E+   +   E +K +E+EE+++         K+E++  + +E E+E
Sbjct: 25  KEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEE 84

Query: 67  EDDYQQKRKGVEGLIDIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMK 126
           E + ++K +G              +  KK         K+  RR+ EE EK+K + R  K
Sbjct: 85  EKEEEEKEEG--------------RRRKK---------KKKRRRKEEEEEKKKKRRRKTK 121



 Score = 33.1 bits (74), Expect = 0.13
 Identities = 18/76 (23%), Positives = 43/76 (56%), Gaps = 1/76 (1%)

Query: 91  QTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLAGKTEQAKADLARLAIIRKQR 150
           + T++  + + +  KE  R+E+ + EK+K KE+  K     K ++ + +  +    RK++
Sbjct: 11  EETEETEETEEEEEKEGKRKEKRK-EKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKK 69

Query: 151 EEAARKKEEERKAKDD 166
           +E   ++EEE + +++
Sbjct: 70  KEEEEREEEEEEEEEE 85



 Score = 30.8 bits (68), Expect = 0.66
 Identities = 17/73 (23%), Positives = 37/73 (50%)

Query: 94  KKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLAGKTEQAKADLARLAIIRKQREEA 153
           KK T+   +  +     E+E   K+K KE+  +     KT++ +    +    +K++ + 
Sbjct: 7   KKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKR 66

Query: 154 ARKKEEERKAKDD 166
            +KKEEE + +++
Sbjct: 67  KKKKEEEEREEEE 79



 Score = 29.3 bits (64), Expect = 1.9
 Identities = 15/65 (23%), Positives = 37/65 (56%), Gaps = 1/65 (1%)

Query: 11  KGRARQYTSPEEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDY 70
           K R R+    +E + + + E+++  EE+E++E  +G     KK+++  + +E + ++   
Sbjct: 60  KKRKRKRKKKKE-EEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118

Query: 71  QQKRK 75
           + K+K
Sbjct: 119 KTKKK 123


>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
          Length = 2115

 Score = 43.5 bits (101), Expect = 1e-04
 Identities = 38/148 (25%), Positives = 70/148 (47%), Gaps = 13/148 (8%)

Query: 22  EIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRKGVEGLI 81
           E++ QL++E+QKA E+E   +  D      +  K+SL   +   EE    +KR+  + L 
Sbjct: 675 ELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEE----EKRRAADAL- 729

Query: 82  DIENPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHL--AGKTEQAKAD 139
             E   R     K  T+       E  +RER+E+E+++A  + ++  L   G+  QA+ +
Sbjct: 730 --EEQQRCISELKAETR----SLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAETE 783

Query: 140 LARLAIIRKQREEAARKKEEERKAKDDA 167
           + R  +      +   + E E+  K+ A
Sbjct: 784 VLRRELAEAMAAQHTAESECEQLVKEVA 811



 Score = 28.5 bits (62), Expect = 3.3
 Identities = 28/152 (18%), Positives = 68/152 (44%), Gaps = 14/152 (9%)

Query: 21  EEIDAQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRKGVEGL 80
           E++ + L+ ++Q+ +E  E++E         +++     +  +E+ E   +++   ++ L
Sbjct: 554 EQLSSSLKQKEQQLKEVAEKQEA-------TRQDHAQQLATAAEEREASLRERDAALKQL 606

Query: 81  IDIENPN----RVAQTTKKVTQLDLDGPK-ELSRREREEIEKQKAKERYMKMHLAGKTEQ 135
             +E        + Q   +V     D  +  +++ +RE+ E  +  E         + EQ
Sbjct: 607 EALEKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREKAELSRKVEELQACVETARQEQ 666

Query: 136 --AKADLARLAIIRKQREEAARKKEEERKAKD 165
             A+A +A L +  +  ++ A +KE   + KD
Sbjct: 667 HEAQAQVAELELQLRSEQQKATEKERVAQEKD 698



 Score = 26.9 bits (58), Expect = 9.6
 Identities = 27/113 (23%), Positives = 48/113 (42%), Gaps = 17/113 (15%)

Query: 25   AQLQAEKQKAREEEEQKEGGDGAAGDPKKEKKSLDSDESEDEEDDYQQKRKGVEGLIDIE 84
            + L+ E      +  +KEG         KE K L   ESE  +   ++ R     L+  E
Sbjct: 1228 SSLEEEVSILNRQVLEKEG-------ESKELKRLVMAESEKSQKLEERLR-----LLQAE 1275

Query: 85   NPNRVAQTTKKVTQLDLDGPKELSRREREEIEKQKAKERYMKMHLAGKTEQAK 137
              +  A+  ++ + L     +E  +  REE EKQ+     ++  L  + E+A+
Sbjct: 1276 TASNSARAAERSSAL-----REEVQSLREEAEKQRVASENLRQELTSQAERAE 1323


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.302    0.124    0.320 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,244,962
Number of Sequences: 37866
Number of extensions: 369069
Number of successful extensions: 9177
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 521
Number of HSP's successfully gapped in prelim test: 712
Number of HSP's that attempted gapping in prelim test: 3439
Number of HSP's gapped (non-prelim): 3995
length of query: 181
length of database: 18,247,518
effective HSP length: 96
effective length of query: 85
effective length of database: 14,612,382
effective search space: 1242052470
effective search space used: 1242052470
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 58 (26.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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