Guide to the Human Genome
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Search of human proteins with 73486664

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo
sapiens]
         (678 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo s...  1475   0.0  
gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo s...  1427   0.0  
gi|11386161 alpha 2 type IX collagen [Homo sapiens]                   777   0.0  
gi|119508426 alpha 3 type IX collagen [Homo sapiens]                  674   0.0  
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...   560   e-159
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...   558   e-159
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...   557   e-158
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]     552   e-157
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]     548   e-156
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...   544   e-155
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...   538   e-153
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]               538   e-153
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]     538   e-153
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]      536   e-152
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]      534   e-152
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]              530   e-150
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...   526   e-149
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...   526   e-149
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...   526   e-149
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]    525   e-149
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]   523   e-148
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]         517   e-146
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...   516   e-146
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...   516   e-146
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...   516   e-146
gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]       515   e-146
gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]        513   e-145
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...   513   e-145
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...   513   e-145
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...   513   e-145

>gi|73486664 alpha 1 type IX collagen isoform 2 precursor [Homo
           sapiens]
          Length = 678

 Score = 1475 bits (3819), Expect = 0.0
 Identities = 678/678 (100%), Positives = 678/678 (100%)

Query: 1   MAWTARDRGALGLLLLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGP 60
           MAWTARDRGALGLLLLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGP
Sbjct: 1   MAWTARDRGALGLLLLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGP 60

Query: 61  PGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPP 120
           PGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPP
Sbjct: 61  PGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPP 120

Query: 121 GPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYP 180
           GPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYP
Sbjct: 121 GPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYP 180

Query: 181 GLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEK 240
           GLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEK
Sbjct: 181 GLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEK 240

Query: 241 GARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVD 300
           GARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVD
Sbjct: 241 GARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVD 300

Query: 301 GRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNS 360
           GRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNS
Sbjct: 301 GRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNS 360

Query: 361 GKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMK 420
           GKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMK
Sbjct: 361 GKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMK 420

Query: 421 GDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLP 480
           GDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLP
Sbjct: 421 GDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLP 480

Query: 481 GVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKR 540
           GVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKR
Sbjct: 481 GVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKR 540

Query: 541 PDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGER 600
           PDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGER
Sbjct: 541 PDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGER 600

Query: 601 GPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEP 660
           GPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEP
Sbjct: 601 GPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEP 660

Query: 661 ASCTMQAGQRAFNKGPDP 678
           ASCTMQAGQRAFNKGPDP
Sbjct: 661 ASCTMQAGQRAFNKGPDP 678


>gi|73486666 alpha 1 type IX collagen isoform 1 precursor [Homo
           sapiens]
          Length = 921

 Score = 1427 bits (3695), Expect = 0.0
 Identities = 654/655 (99%), Positives = 655/655 (100%)

Query: 24  QRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADG 83
           +RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADG
Sbjct: 267 ERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADG 326

Query: 84  LTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGR 143
           LTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGR
Sbjct: 327 LTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGR 386

Query: 144 RGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGH 203
           RGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGH
Sbjct: 387 RGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGH 446

Query: 204 KGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQ 263
           KGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQ
Sbjct: 447 KGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQ 506

Query: 264 RGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGD 323
           RGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGD
Sbjct: 507 RGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGD 566

Query: 324 AGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGS 383
           AGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGS
Sbjct: 567 AGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGS 626

Query: 384 RGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGE 443
           RGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGE
Sbjct: 627 RGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGE 686

Query: 444 AGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGL 503
           AGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGL
Sbjct: 687 AGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGL 746

Query: 504 PGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGE 563
           PGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGE
Sbjct: 747 PGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGE 806

Query: 564 NGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPA 623
           NGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPA
Sbjct: 807 NGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPA 866

Query: 624 SYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPDP 678
           SYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPDP
Sbjct: 867 SYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPDP 921



 Score =  431 bits (1108), Expect = e-120
 Identities = 266/647 (41%), Positives = 317/647 (48%), Gaps = 108/647 (16%)

Query: 22  AAQRGPPGEQGPPGPPGPPGVPGIDGID---GDRGPKGPPGPPGPAGEPGK--PGAPGKP 76
           A + G PG  G PG PG  G+ G DG     G +G KG PG PG  G PG+  PG PG P
Sbjct: 307 AGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPP 366

Query: 77  GT---PGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGF-------PGRGIPGPPGPPGTA 126
           GT   PG  G  GP G PG  G  G  G PG  G+ GF       P    PG  G PG  
Sbjct: 367 GTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLP 426

Query: 127 GLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGM- 185
           G+ G  G  G +G+PGR+G  G  G  G  G +G            PPG  G  G+ G+ 
Sbjct: 427 GMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQG---------PPGAQGLRGITGIV 477

Query: 186 --RGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGAR 243
             +G KGA+G  GEPG QG  G  GDQG+ G  G  GP G +G  G  GI G  G KG  
Sbjct: 478 GDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDT 537

Query: 244 GLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRD 303
           GL G  G  G+PG PG +G+   PG+ GP GD G +G  G+PG+PG KG  G  G  G  
Sbjct: 538 GLPGVDGRDGIPGMPGTKGE---PGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAP 594

Query: 304 GIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKP 363
           G PG  G  G+PG+ GPPG+ G +   G  G+PG++G  G  GS G PGK G +G+ G P
Sbjct: 595 GKPGQMGNSGKPGQQGPPGEVGPR---GPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLP 651

Query: 364 GQQGPP------------GEVGPRGPQGLPGSRGEL---GPVGSPGLPGKLGSLGSPGLP 408
           G  GPP            GE GP+G QG  G  GE    G +G  GLPG  GS G+PG P
Sbjct: 652 GLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEP 711

Query: 409 GLPGPP---GLPGMKGDRGVVGEPGPKGEQGASGEEGEAG-------------------- 445
           GL GP    GLPG++G RG  G  G +GEQGA+G  G  G                    
Sbjct: 712 GLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQ 771

Query: 446 ----------ERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQ 495
                     +R + G  GLPG  G  G PG PG  G  G  G+ G+ G +GPPG  G++
Sbjct: 772 EHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLR 831

Query: 496 GEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPP 555
           G +G  G  G +GPPGR P                             GA GLPG PGP 
Sbjct: 832 GPKGDLGEKGERGPPGRGPNGL-------------------------PGAIGLPGDPGPA 866

Query: 556 --GPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGER 600
             G  G  GE G PG  GI G+PG  GPPG  G   P     + G+R
Sbjct: 867 SYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQR 913



 Score =  357 bits (917), Expect = 2e-98
 Identities = 223/514 (43%), Positives = 256/514 (49%), Gaps = 55/514 (10%)

Query: 174 PGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGEL------GEVGAQGPPGAQGL 227
           P R     LP          E G PG QG  G  G  G        G+ G +GPPG  G 
Sbjct: 247 PRRETCHELPARITPSQTTDERGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGP 306

Query: 228 RGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGL 287
            G  G  G  G+ G  G DG  GP G PG+ G +GQ+G PG  G +G  G    RGIPG 
Sbjct: 307 AGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----RGIPGP 362

Query: 288 PGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGL------------PGVPGI 335
           PGP G  GLPG  GR G  G PG +G PG PGPPG  G  G             PG  G 
Sbjct: 363 PGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGY 422

Query: 336 PGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGL 395
           PG  G+ G KG+ G  G+PG+ G+ G+ G QG  GEVG +GP G  G RG  G VG  G 
Sbjct: 423 PGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGE 482

Query: 396 PGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGL 455
            G  G  G PG  GL   PG PG +G RG  GE GPKG++GA G  G  G  G  GD GL
Sbjct: 483 KGARGLDGEPGPQGL---PGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGL 539

Query: 456 PGPKGSAGNP------GEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGP 509
           PG  G  G P      GEPG  GP G  GL G+ G  G PG +GV GE+G+TG PG  G 
Sbjct: 540 PGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQ 599

Query: 510 PGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQ 569
            G +                   +     +    G  GLPG  G  GP G PG  G  G 
Sbjct: 600 MGNSGKP---------------GQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGS 644

Query: 570 MGIRGLPGIKGPPGALGLRGPKGDLGE---KGERGPPGR----GPNGLPGAIGLPGDPGP 622
           +G  GLPG+ GPPG  G++G +G +GE   KGE+G  G     G  G  G IGLPG  G 
Sbjct: 645 LGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGS 704

Query: 623 ASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
           A  G  G  G RGP G  G+PGV GP GPPG  G
Sbjct: 705 A--GNPGEPGLRGPEGSRGLPGVEGPRGPPGPRG 736



 Score =  314 bits (804), Expect = 2e-85
 Identities = 197/474 (41%), Positives = 234/474 (49%), Gaps = 69/474 (14%)

Query: 9   GALGLLLLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPG 68
           GA GL   G+      +G  G +G  G PGP G+PG  G  G RGP G  GP G  G  G
Sbjct: 466 GAQGLR--GITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEG 523

Query: 69  KPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPP---- 123
             G PG PG  G  GL G DG  G  G  G KGEPG PG  G  G +G+PG PG P    
Sbjct: 524 ARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKG 583

Query: 124 -----GTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHD-----GDPLCPNAC- 172
                G+ G PG+ G++G  G PG++GPPG  GP GP+G  G        G P  P    
Sbjct: 584 VAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLG 643

Query: 173 ---PPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRG 229
               PG  G PG PG+ G KG +G +GEP   G KGE+G  GE GE G +G  G  GL G
Sbjct: 644 SLGSPGLPGLPGPPGLPGMKGDRGVVGEP---GPKGEQGASGEEGEAGERGELGDIGLPG 700

Query: 230 ITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPG 289
             G  G+ GE G R      GP+G  G PG +G RGPP   GP+G +G +GA G+PG+ G
Sbjct: 701 PKGSAGNPGEPGLR------GPEGSRGLPGVEGPRGPP---GPRGVQGEQGATGLPGVQG 751

Query: 290 PKG------------------------------DTGLPGVDGRDGIPGMPGTKGEPGKPG 319
           P G                              D+G  G+ GR   PG PG  G PG+ G
Sbjct: 752 PPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGR---PGPPGPPGPPGENG 808

Query: 320 PPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGN--SGKPGQQGPPGEVGPRGP 377
            PG  G++GLPG+ G PGA G+ G KG  G  G+ G  G   +G PG  G PG+ GP   
Sbjct: 809 FPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGP-AS 867

Query: 378 QGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGP 431
            G  G  GE GP G  G+PG  G  G PGLPG   P       G R     P P
Sbjct: 868 YGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPDP 921


>gi|11386161 alpha 2 type IX collagen [Homo sapiens]
          Length = 689

 Score =  777 bits (2007), Expect = 0.0
 Identities = 376/667 (56%), Positives = 432/667 (64%), Gaps = 5/667 (0%)

Query: 2   AWTARDRGALGLLLLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPP 61
           A TA  R  L LL + +   A  RGPPGE+GPPGPPGPPGVPG DGIDGD GP G  GPP
Sbjct: 3   AATASPRSLLVLLQVVVLALAQIRGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPP 62

Query: 62  GPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPG 121
           GP GEPGK G  G  G PG DGLTG  G PG +G  G KG+PG+PG  G PG G  GPPG
Sbjct: 63  GPKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPG 122

Query: 122 PPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDG-----DPLCPNACPPGR 176
           PPG  GLPGE+G  GP GDPG  GP GPPGPPG  G  G   G     D LCP  CPPG 
Sbjct: 123 PPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGM 182

Query: 177 SGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGD 236
            G PGL G++GH G +G +G+PG QG  G +GD G  GE G  GPPG QG+RG  G+ G 
Sbjct: 183 KGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGP 242

Query: 237 KGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGL 296
           KGE G  G  G  G  G  G PG++G RGPPG AG KGD G+ G RG  G+ GPKG TG 
Sbjct: 243 KGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGP 302

Query: 297 PGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQ 356
           PG++G+DG PG PG KG  G+ G PG  G QGL GVPG PG KG  G++G  G  G PG 
Sbjct: 303 PGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGF 362

Query: 357 MGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGL 416
            G  GK G+ GP GE+GP+G  G  G +GE GPVG PG  G+ G  G  G PG+PGP GL
Sbjct: 363 SGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGL 422

Query: 417 PGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGS 476
           PG+KGD+G  G+ GP+G+ G  G  G  GE+GE G+ G PGPKG  G  GEPG  GP G 
Sbjct: 423 PGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGD 482

Query: 477 RGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAA 536
            G PGV+G  GPPGPRG+ G +G  G PG QG  GR  TDQHI  V ++++QE  AE+A 
Sbjct: 483 AGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAV 542

Query: 537 SLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGE 596
           S KR   GA G+ G PGPPGPPG PG+ G  G  G RG+PGI G  G +G  GPKG  GE
Sbjct: 543 SAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGE 602

Query: 597 KGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
           KG+ G  GRG  G+PG  G+PG PG      NG+DG+RG PG  G  G PG PGP GLPG
Sbjct: 603 KGDPGEVGRGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPG 662

Query: 657 FCEPASC 663
           FCEPA+C
Sbjct: 663 FCEPAAC 669



 Score =  400 bits (1027), Expect = e-111
 Identities = 248/624 (39%), Positives = 292/624 (46%), Gaps = 99/624 (15%)

Query: 109 RGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLC 168
           RG PG    GPPGPPG  G+PG  G  G  G PG+ GPPGP G PG  G           
Sbjct: 26  RGPPGER--GPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAG----------- 72

Query: 169 PNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGE--VGAQGPPGAQG 226
               P G  G PG+ G+ G KG  G +G PG +G  G  G  G  G    G  GPPG  G
Sbjct: 73  ----PDGPDGKPGIDGLTGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVG 128

Query: 227 LRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGD-----------------QGQRGPPGE 269
           L G  GI G KG+ G  G  G PGP G PG PG                   G +GPPG 
Sbjct: 129 LPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGL 188

Query: 270 AGPKGDRGAEGARGIPG---LPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGL 326
            G KG  G  G  G PG    PGPKGD G  G  G  G PG  G +G PG  GP G+ G 
Sbjct: 189 QGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGP 248

Query: 327 QGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGE 386
            G  G+ G  GA G  GE+G  G PG+ G+ G+ G PG +GP G  GP+G  G PG  G+
Sbjct: 249 HGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGK 308

Query: 387 LGPVGSPGLPGKLGSLGSPGLPG---LPGPPGLPGMKGDRGVVGEPGPKGEQGASG---E 440
            G  G+PG+ G  G  G PG PG   L G PG PG KG  G  GEPGP+G  G SG   +
Sbjct: 309 DGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGK 368

Query: 441 EGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGA 500
           EGE G RGE+G  G+ G KG  G  G  G  GP+G +G  G +GP G PGP+G+ G +G 
Sbjct: 369 EGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGD 428

Query: 501 TGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGP 560
            G PG  GP G+                    +   +    + G  G  G PGP G  G 
Sbjct: 429 KGSPGKTGPRGKV------------------GDPGVAGLPGEKGEKGESGEPGPKGQQGV 470

Query: 561 PGENGFPGQMGIRGLPGIKG---PPGALGLRGPKGDLGEKGERGPPGRGPNGLP------ 611
            GE G+PG  G  G PG++G   PPG  GL G +G  G+ G +G  GR            
Sbjct: 471 RGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVAL 530

Query: 612 -------------------GAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPP 652
                              GA+G+ G PGP         G  G PG  G  G PGP G P
Sbjct: 531 KMLQEQLAEVAVSAKREALGAVGMMGPPGPP--------GPPGYPGKQGPHGHPGPRGVP 582

Query: 653 GLPGFCEPASCTMQAGQRAFNKGP 676
           G+ G       T   G+R     P
Sbjct: 583 GIVGAVGQIGNTGPKGKRGEKGDP 606



 Score =  338 bits (866), Expect = 1e-92
 Identities = 220/570 (38%), Positives = 256/570 (44%), Gaps = 161/570 (28%)

Query: 26  GPPGEQGP--PGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGT----- 78
           GPPG  GP   GPPGPPG  G+ G  G RGPKG PGP GP+G PG PG PG+PGT     
Sbjct: 108 GPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLE 167

Query: 79  ------------------PGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGP 119
                             PG  G+ G  G  G +G  G +G+PG  G  G  G +GIPGP
Sbjct: 168 GSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGEQGIPGP 227

Query: 120 PGPPGTAGLPGELG---RVGP------VGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPN 170
           PGP G  G PG  G     GP      VG  G  GPPG  GP GP G  G   GD   P 
Sbjct: 228 PGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAG-EKGDEGSPG 286

Query: 171 ACPP----------------GRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELG 214
              P                G+ G PG PGM+G  G  G+ G PG QG  G  G  G  G
Sbjct: 287 IRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKG 346

Query: 215 EVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKG 274
             G QG PG QGL G +G  G +GE G RG   E GPQG+ G  GDQG+RGP G+ GP+G
Sbjct: 347 GPGDQGEPGPQGLPGFSGPPGKEGEPGPRG---EIGPQGIMGQKGDQGERGPVGQPGPQG 403

Query: 275 DRGAEGARGIPGLPGP------KGDTGLPGVDGR------DGIPGMPGTKGE-------- 314
            +G +G +G PG+PGP      KGD G PG  G        G+ G+PG KGE        
Sbjct: 404 RQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPG 463

Query: 315 ----------PGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGK----------- 353
                     PG PGP GDAG  G+ G PG PG +G+AG +G  G PG+           
Sbjct: 464 PKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQ 523

Query: 354 ----------------------------------PGQMGNSGKPGQQGPPGEVGPRGPQG 379
                                             PG  G  G PG+QGP G  GPRG  G
Sbjct: 524 HIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGVPG 583

Query: 380 LPGSRGELG--------------------------PVGSPGLPGKLGSL-----GSPGLP 408
           + G+ G++G                          P G PGLPG+ G       G  G P
Sbjct: 584 IVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSP 643

Query: 409 GLPGPPGLPGMKGDRGVVGEPGPKGEQGAS 438
           G PG  G PG+ G  G+ G   P    GAS
Sbjct: 644 GAPGEAGRPGLPGPVGLPGFCEPAACLGAS 673



 Score =  326 bits (836), Expect = 4e-89
 Identities = 192/472 (40%), Positives = 229/472 (48%), Gaps = 30/472 (6%)

Query: 237 KGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGL 296
           +G  G RG  G PGP G+PG+ G  G  GPPG+AGP G +G  G  G  G  G  G  GL
Sbjct: 26  RGPPGERGPPGPPGPPGVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGL 85

Query: 297 PGVDGRDGIPGMPGTKGEPGKPGPPG-----DAGLQGLPGVPGIPGAKGVAGEKGSTGAP 351
            G  G  G  G+PG KG+PG PGPPG      AG  G PG  G+PG  G+ G KG  G  
Sbjct: 86  TGAKGEPGPMGIPGVKGQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKGDPGPD 145

Query: 352 GKPGQMGNSGKPGQQG-----------------PPGEVGPRGPQGLPGSRGELGPVGSPG 394
           G  G  G  GKPG+ G                 PPG  GP G QG+ G  G+ G +G PG
Sbjct: 146 GPSGPPGPPGKPGRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPG 205

Query: 395 LPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIG 454
             GK G  G  G  G  G PG PG +G RG  G  GPKGE G  G +G  G  G  G  G
Sbjct: 206 HQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPG 265

Query: 455 LPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAP 514
             GP+G  G  GE G  G  G RG  G+ GP+G  GP G+ G+ G  G PG++G  G+A 
Sbjct: 266 EEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAG 325

Query: 515 TDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRG 574
                    +  +            + + G  GLPG  GPPG  G PG  G  G  GI G
Sbjct: 326 QPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMG 385

Query: 575 LPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGPASY-------G 626
             G +G  G +G  GP+G  G KGE+GPPG  GP GLPG  G  G PG           G
Sbjct: 386 QKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPG 445

Query: 627 RNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPDP 678
             G  GE+G  G +G PG  G  G  G PG+  P+      G + +   P P
Sbjct: 446 VAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGP 497



 Score =  267 bits (683), Expect = 2e-71
 Identities = 173/429 (40%), Positives = 198/429 (46%), Gaps = 104/429 (24%)

Query: 26  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 85
           GPPGE+GP GPPG  G  G +G  G RGP+G  GP G  G PG  G  G PGTPG  G  
Sbjct: 262 GPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSA 321

Query: 86  GPDGSPGSIGSKGQKGEPGVPGSRGFPG-------RGIPGPPGPPGTAGLPGELGRVGPV 138
           G  G PGS G +G  G PG PG++G PG       +G+PG  GPPG  G PG  G +GP 
Sbjct: 322 GQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQ 381

Query: 139 G------DPGRRGPPGPPGP---------------PGPRGTIGFHDGDPLCPNACPP-GR 176
           G      D G RGP G PGP               PGP+G  G   GD   P    P G+
Sbjct: 382 GIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVK-GDKGSPGKTGPRGK 440

Query: 177 SGYPGLPGMRGHKGAKGEIGEPG---RQGHKGEEGDQGELGEVGAQG------PPGAQGL 227
            G PG+ G+ G KG KGE GEPG   +QG +GE G  G  G+ GA G      PPG +GL
Sbjct: 441 VGDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGL 500

Query: 228 RGITGIVGDKGEKGARGLD------------------------------------GEPGP 251
            G  G+ G  G +G  G D                                    G PGP
Sbjct: 501 AGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPGP 560

Query: 252 QGLPGAPGDQGQRGPPG---------------EAGPKGDRGAEG-----ARGIPGLPGPK 291
            G PG PG QG  G PG                 GPKG RG +G      RG PG+PGP 
Sbjct: 561 PGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGHPGMPGPP 620

Query: 292 GDTGLPG-----VDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAG--- 343
           G  GLPG     ++G+DG  G PG  GE G+PG PG  GL G        GA   A    
Sbjct: 621 GIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLGASAYASARL 680

Query: 344 -EKGSTGAP 351
            E GS   P
Sbjct: 681 TEPGSIKGP 689


>gi|119508426 alpha 3 type IX collagen [Homo sapiens]
          Length = 684

 Score =  674 bits (1738), Expect = 0.0
 Identities = 333/658 (50%), Positives = 413/658 (62%), Gaps = 10/658 (1%)

Query: 13  LLLLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGA 72
           LLLLG  L AA     G  GPPGPPGPPG PG DGIDG+ GP G PGPPGP G PGKPG 
Sbjct: 13  LLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGK 72

Query: 73  PGK---PGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLP 129
           PG+   PG PG DGLTG DG PG  G+ G++G  G PG  G  G+G+PGPPG  G +G P
Sbjct: 73  PGEAGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPGEAGVSGPP 132

Query: 130 GELGRVGPVGD---PGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMR 186
           G +G  GP G    PG  GPPGPPGPPG  G +     D  CP+ CPPG  G PG+PG +
Sbjct: 133 GGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFK 192

Query: 187 GHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLD 246
           G  G KGE GE G+ G KG+ G  G  G  G+ G  G +GLRG+ G +G  G++G  G  
Sbjct: 193 GPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFR 252

Query: 247 GEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIP 306
           G PG  G PG  GD+G+RGP G  GPKGD G  G +G PG+ GP G+ G+PG DG++G+P
Sbjct: 253 GPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVP 312

Query: 307 GMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQ 366
           G+ G KGE G+ G PG+ G  GLPG+PG  G+KG  GE+G  G  G+ G  G  G PG  
Sbjct: 313 GLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAGPSGEPGVPGDA 372

Query: 367 GPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVV 426
           G PGE G  G +G  G+ G  GP G+PG+ G  G  GS G PGLPGP GL G  GDRG  
Sbjct: 373 GMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPG 432

Query: 427 GEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPR 486
           G  GPKG+QG +G +G  G++GELG  GL GPKG +G+ GE G +G +G  G  GV+G  
Sbjct: 433 GAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVP 492

Query: 487 GPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRP-DSGA 545
           GPPGP G+QG  G  G+ G  G PG+  ++Q I+++C  +I E  A++AA L++P   G+
Sbjct: 493 GPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGS 552

Query: 546 TGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR 605
            G PG  GPPGPPGPPG  G P   G RG PG +GP G LG  GP+G+ G++G++G  G 
Sbjct: 553 IGRPGPAGPPGPPGPPGSIGHP---GARGPPGYRGPTGELGDPGPRGNQGDRGDKGAAGA 609

Query: 606 GPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASC 663
           G +G  G  G  G  G     ++G+DG  G PG  G PG+PG  G  G PG C+ ++C
Sbjct: 610 GLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTPGICDTSAC 667



 Score =  395 bits (1014), Expect = e-110
 Identities = 255/626 (40%), Positives = 291/626 (46%), Gaps = 120/626 (19%)

Query: 115 GIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPP 174
           G+PGPPGPPG  G PG+ G  G  G PG  GPPGP G PG  G                P
Sbjct: 29  GLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGK---------------P 73

Query: 175 GRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPG--AQGLRGITG 232
           G +G PGLPG+ G  G         R G  G +G  GE G +G  GPPG   +GL G  G
Sbjct: 74  GEAGLPGLPGVDGLTG---------RDGPPGPKGAPGERGSLGPPGPPGLGGKGLPGPPG 124

Query: 233 IVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAG--PKGDR----------GAEG 280
             G  G  G  GL G PGP GLPG PG  G  GPPG  G  P+G            G  G
Sbjct: 125 EAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPG 184

Query: 281 ARGIPGLPGP---KGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPG 337
             G+PG  GP   KG+ G  G DG  G PG PG  G PG  G  G  GL+GLPG  G PG
Sbjct: 185 PPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPG 244

Query: 338 AKGVAGEKGSTGAPGKPGQMGNSGKPGQQG---PPGEVGPRGPQGLPGSRGELGPVGSPG 394
            +G  G +G  G PG PG+ G+ G+ G +G   P G++G  GP+G PG  G   P G PG
Sbjct: 245 DRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAG---PSGEPG 301

Query: 395 LPGKLGSLGSPGLPGLPGPPG---LPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELG 451
           +PGK G  G PGL G  G  G    PG KG  G+ G PG  G +G  GE G AGE GE G
Sbjct: 302 MPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEAG 361

Query: 452 DIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPG 511
             G PG  G AG PGE G  G  GS G  G +GP G PG RG QG++G+ G PG+ GP G
Sbjct: 362 PSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQG 421

Query: 512 RAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMG 571
                                       R D G  G  G  GP G  G  G +G PG  G
Sbjct: 422 L---------------------------RGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKG 454

Query: 572 IRGLPGIKGPPGALGLRG---------PKGDLGEKGERGPPG----RGPNGLPGAIGLPG 618
             G  G+ GP G  G RG         P G  G +G  GPPG    +G  G+PG  G PG
Sbjct: 455 ELGPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPG 514

Query: 619 DPG-----------------------------PASYGRNGRDGERGPPGVAGIPGVPGPP 649
            PG                             P + G  GR G  GPPG  G PG  G P
Sbjct: 515 VPGKEASEQRIRELCGGMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHP 574

Query: 650 GPPGLPGFCEPASCTMQAGQRAFNKG 675
           G  G PG+  P       G R  N+G
Sbjct: 575 GARGPPGYRGPTGELGDPGPRG-NQG 599



 Score =  353 bits (906), Expect = 3e-97
 Identities = 226/552 (40%), Positives = 259/552 (46%), Gaps = 142/552 (25%)

Query: 26  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPG---------------KP 70
           GPPGE G  GPPG  G+ G  G  G  G  GPPGPPGP G PG                P
Sbjct: 121 GPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPP 180

Query: 71  GAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----------RGIPGPP 120
           G PG PG PG  G TG  G  G +G  G+KG+PG PG  G PG          RG+PGP 
Sbjct: 181 GPPGPPGMPGFKGPTGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPL 240

Query: 121 GPPGTAGL------PGELGRVGPVGDPGRRGPPGPPGP------PGPRGTIGFH--DGDP 166
           GPPG  G       PG  G  G  GD G RGP G  GP      PGP+GT G     G+P
Sbjct: 241 GPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEP 300

Query: 167 LCPNACPPGRSGYPGLPGMRGHKGAKGEIGE---------PGRQGHKGEEGDQGELGEVG 217
             P     G++G PGL G +G  G  G  GE         PGR G KGE+G++G  GE+G
Sbjct: 301 GMPGK--DGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELG 358

Query: 218 AQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPG------------------ 259
             GP G  G+ G  G+ G++GE G RG  G  GPQG PGAPG                  
Sbjct: 359 EAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPG 418

Query: 260 ------DQGQRGPPGEAGPKGDRGAEGARGIPG---------LPGPKGDTGLPGVDGRDG 304
                 D G RGP G AGPKGD+G  G+ G+PG         L GPKG++G  G  G  G
Sbjct: 419 PQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKG 478

Query: 305 IPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEK------------------- 345
             G  GT G  G PGPPG  GLQG+PGVPGI G  GV G++                   
Sbjct: 479 TQGPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIA 538

Query: 346 ------------------GSTGAPGKPGQMGNSGKPGQQGPPG---------EVGPRGPQ 378
                             G  G PG PG  G+ G PG +GPPG         + GPRG Q
Sbjct: 539 QLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQ 598

Query: 379 G-----------LPGSRGELGPVGSPGLPG--KLGSLGSPGLPGLPGPPGLPGMKGDRGV 425
           G           L G  G+ GP G  G+PG  K G  G+PG PG PG PGLPG  G +G 
Sbjct: 599 GDRGDKGAAGAGLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGT 658

Query: 426 VGEPGPKGEQGA 437
            G       QGA
Sbjct: 659 PGICDTSACQGA 670



 Score =  322 bits (826), Expect = 5e-88
 Identities = 205/500 (41%), Positives = 242/500 (48%), Gaps = 55/500 (11%)

Query: 213 LGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGP 272
           LGE+ A       GL G  G  G  G+ G  G+DGE GP GLPG PG +G  G PG+ G 
Sbjct: 16  LGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGE 75

Query: 273 KGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGV 332
            G  G  G  G+ G  GP G  G PG  G  G PG PG  G+ G PGPPG+AG+ G PG 
Sbjct: 76  AGLPGLPGVDGLTGRDGPPGPKGAPGERGSLGPPGPPGLGGK-GLPGPPGEAGVSGPPGG 134

Query: 333 PGIPGAKGVAGEKGSTGAPGKPGQMGNSG---------------KPGQQGPPGEVGPRGP 377
            G+ G  G +G  G  G PG PG  G+ G                PG  GPPG  G +GP
Sbjct: 135 IGLRGPPGPSGLPGLPGPPGPPGPPGHPGVLPEGATDLQCPSICPPGPPGPPGMPGFKGP 194

Query: 378 QGLPGSRGELG---------PVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGD---RGV 425
            G  G +GE+G         P G  GLPG +G  G  GL GLPGP G PG +G    RG 
Sbjct: 195 TGYKGEQGEVGKDGEKGDPGPPGPAGLPGSVGLQGPRGLRGLPGPLGPPGDRGPIGFRGP 254

Query: 426 VGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGS---AGNPGEPGLRGPEGSRGLPGV 482
            G PG  G+ G  GE G  G RG  GD+G PGPKG+   AG  GEPG+ G +G  G+PG+
Sbjct: 255 PGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEPGMPGKDGQNGVPGL 314

Query: 483 EGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPD 542
           +G +G  G  G  GE+G  GLPG+   PGRA +                 E     +  +
Sbjct: 315 DGQKGEAGRNGAPGEKGPNGLPGL---PGRAGSK---------------GEKGERGRAGE 356

Query: 543 SGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGP 602
            G  G  G PG PG  G PGE G  G  G  G  G +GPPGA G+RG +G  G  G+ G 
Sbjct: 357 LGEAGPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGL 416

Query: 603 PGRGPNGLPGAIGLPGDPGPAS----YGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFC 658
           PG  P GL G +G  G  G A      G  G DG  G  G  G  G+ GP G  G  G  
Sbjct: 417 PG--PQGLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGEL 474

Query: 659 EPASCTMQAGQRAFNKGPDP 678
            P       G       P P
Sbjct: 475 GPKGTQGPNGTSGVQGVPGP 494



 Score =  250 bits (639), Expect = 3e-66
 Identities = 167/442 (37%), Positives = 191/442 (43%), Gaps = 120/442 (27%)

Query: 26  GPPGEQGPPGPPGPPGVPGIDGIDGDRG------------------PKGPPGPPGPAGEP 67
           GPPG++GP G  GPPG+PG  G  GDRG                  PKG PG  GP+GEP
Sbjct: 241 GPPGDRGPIGFRGPPGIPGAPGKAGDRGERGPEGFRGPKGDLGRPGPKGTPGVAGPSGEP 300

Query: 68  GKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR------------- 114
           G PG  G+ G PG DG  G  G  G+ G KG  G PG+PG  G  G              
Sbjct: 301 GMPGKDGQNGVPGLDGQKGEAGRNGAPGEKGPNGLPGLPGRAGSKGEKGERGRAGELGEA 360

Query: 115 GIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHD--GDPLCPN-- 170
           G  G PG PG AG+PGE G  G  G  G  GP GPPG PG RG  G     GDP  P   
Sbjct: 361 GPSGEPGVPGDAGMPGERGEAGHRGSAGALGPQGPPGAPGVRGFQGQKGSMGDPGLPGPQ 420

Query: 171 -----------ACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQ 219
                          G  G  G+ G  G  G KGE+G  G  G KGE G +GELG  G Q
Sbjct: 421 GLRGDVGDRGPGGAAGPKGDQGIAGSDGLPGDKGELGPSGLVGPKGESGSRGELGPKGTQ 480

Query: 220 GP------------PGAQGLRGITGIVGDKGEKGARGLD--------------------- 246
           GP            PG  GL+G+ G+ G  G+ G  G +                     
Sbjct: 481 GPNGTSGVQGVPGPPGPLGLQGVPGVPGITGKPGVPGKEASEQRIRELCGGMISEQIAQL 540

Query: 247 -------------------GEPGPQGLPGAPGDQGQRGPPGEAGP------------KGD 275
                              G PGP G PG+ G  G RGPPG  GP            +GD
Sbjct: 541 AAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELGDPGPRGNQGD 600

Query: 276 RGAEGARGIPGLPGPKGDTGLPGVDG-----RDGIPGMPGTKGEPGKPGPPGDAGLQGLP 330
           RG +GA G  GL GP+GD G  G  G     +DG  G PG  G PG PG PG  G QG P
Sbjct: 601 RGDKGAAGA-GLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGLPGAIGAQGTP 659

Query: 331 GVPGIPGAKGV----AGEKGST 348
           G+      +G      GEK  +
Sbjct: 660 GICDTSACQGAVLGGVGEKSGS 681



 Score = 92.0 bits (227), Expect = 2e-18
 Identities = 55/131 (41%), Positives = 63/131 (48%), Gaps = 4/131 (3%)

Query: 12  GLLLLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGD---RGPKGPPGPPGPAGEPG 68
           G++   +   AA    P   G  G PGP G PG  G  G     G +GPPG  GP GE G
Sbjct: 531 GMISEQIAQLAAHLRKPLAPGSIGRPGPAGPPGPPGPPGSIGHPGARGPPGYRGPTGELG 590

Query: 69  KPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGL 128
            PG  G  G  G  G  G  G  G  G +G +G  GVPG+      G PG PGPPG  GL
Sbjct: 591 DPGPRGNQGDRGDKGAAGA-GLDGPEGDQGPQGPQGVPGTSKDGQDGAPGEPGPPGDPGL 649

Query: 129 PGELGRVGPVG 139
           PG +G  G  G
Sbjct: 650 PGAIGAQGTPG 660



 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 35/92 (38%), Positives = 40/92 (43%), Gaps = 14/92 (15%)

Query: 7   DRGALGLLLLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGE 66
           DRG  G    GL      +GP G QG PG                 G  G PG PGP G+
Sbjct: 600 DRGDKGAAGAGLDGPEGDQGPQGPQGVPG-------------TSKDGQDGAPGEPGPPGD 646

Query: 67  PGKPGAPGKPGTPGADGLTGPDGSP-GSIGSK 97
           PG PGA G  GTPG    +   G+  G +G K
Sbjct: 647 PGLPGAIGAQGTPGICDTSACQGAVLGGVGEK 678


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score =  560 bits (1442), Expect = e-159
 Identities = 337/750 (44%), Positives = 392/750 (52%), Gaps = 140/750 (18%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPG-----PPGPAGEPGKPGAPGKPGTPG 80
            G  G+ G PG PG PG PG+ GI G +G  G PG     PPGP G PG PG PG PGTPG
Sbjct: 672  GRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPG 731

Query: 81   ADGLTGPDGSPGSIGSKGQKGE--PGVPGSRGFPG----------RGIPGPPGPPGTAGL 128
              GL GP G PG  G KG+ G   PG PG  G PG          RG PGPPGPPG  GL
Sbjct: 732  RIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGL 791

Query: 129  ---PGELGRVGPVGDPGR-----------RGPPGPPGPPGPRGTIGFHD-----GDPLCP 169
               PG  G VGP G PG            +GPPGPPG PGP G  G H      GDP  P
Sbjct: 792  DGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPP 851

Query: 170  NAC---PPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQG 226
                  PPG  G PG+PG  G  G  G  G PG+ G  G  G +GE+G +G  GPPG  G
Sbjct: 852  GLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLG 911

Query: 227  LRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGP-----KGDRGAEGA 281
            + G +G+ G KG+ G +G  G PGP G  G+ G+ G  GPPG   P     KG++G  G 
Sbjct: 912  IPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGL 971

Query: 282  RGIPGLPGPKG------DTGLPGVDGRDGIPGMPGTKGEPGKPGPPG------------D 323
             GIPG+ GPKG      D G PG+ G+ G+PG PG KG PG PG PG            D
Sbjct: 972  PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGD 1031

Query: 324  AGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSG-----KPGQQGPPGEVGPRGPQ 378
             G  G  GV G PG  GV G+ GS G PG+ G  G+ G      PG  GP GE G  G  
Sbjct: 1032 MGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYP 1091

Query: 379  GLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKG------DRGVVGEPGPK 432
            G PG +G +G  G PGLPG  G+ G PGLPG PG PG PG KG      + G+ GEPGP 
Sbjct: 1092 GNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPV 1151

Query: 433  GEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPG-----------LRGPEGSRGLPG 481
            G  G  G+ G  GE+G+ G  G+PGP G  G PG+PG           L G +G  GLPG
Sbjct: 1152 GGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPG 1211

Query: 482  VEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRP 541
            + G  G PGP+G   E G  G PGVQGPPG   +                     +L+ P
Sbjct: 1212 IPGNPGLPGPKG---EPGFHGFPGVQGPPGPPGSP------------------GPALEGP 1250

Query: 542  --DSGATGLPGRPGPPGPPGPPG---------ENGFPGQMGIRGLPGIKGP--------- 581
              + G  G PGRPG PGP GPPG         E G PGQ G+ GLPG+KG          
Sbjct: 1251 KGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGN 1310

Query: 582  PGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPG-------PASYGRNGRD-- 631
            PG  GL G KGD G  G  G PG +GP+G+PG+ G  G+PG       P   G +G+   
Sbjct: 1311 PGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSII 1370

Query: 632  --GERGPPGVAGIP---GVPGPPGPPGLPG 656
              G+ GPPG+ G P   G+PGP GP GLPG
Sbjct: 1371 IKGDAGPPGIPGQPGLKGLPGPQGPQGLPG 1400



 Score =  551 bits (1421), Expect = e-157
 Identities = 325/695 (46%), Positives = 370/695 (53%), Gaps = 82/695 (11%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 85
            GP G++G PGPPGPPG  G+DG+ G +G  GP G PGP G PG PG  G  G PG  G+ 
Sbjct: 772  GPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI-GVQGPPGPPGIP 830

Query: 86   GPDGSPGSIGSKGQKGEPGVPG--------SRGFPG-RGIPGPPGPPGTAGLPGELGRVG 136
            GP G PG  G  G+KG+PG PG         RG PG  G PGP GPPG+ GLPG+ G  G
Sbjct: 831  GPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASG 890

Query: 137  PVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIG 196
              G  G  G  GPPGPPGP G  G   G P        G  G PGLPG  G KG+KGE G
Sbjct: 891  FPGTKGEMGMMGPPGPPGPLGIPG-RSGVPGLKG--DDGLQGQPGLPGPTGEKGSKGEPG 947

Query: 197  EPGRQGHKGEE--GDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARG---LDGEPGP 251
             PG  G       G +GE GE G  G PG  G +G  G+ GD G+ G  G   L G PGP
Sbjct: 948  LPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGP 1007

Query: 252  QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGI---------------PGLPGPKGDTGL 296
            +G PG PG  G  GPPG  G  GD G  G +G+               PGLPG KGD G 
Sbjct: 1008 KGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGD 1067

Query: 297  PGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQG------LPGVPGIPGAKGVAGEKGSTGA 350
            PG+    G+PG+PG KGEPG PG PG+ G++G      LPG+PG PGAKG  G  G  G 
Sbjct: 1068 PGISSI-GLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGT 1126

Query: 351  PGKPGQMGNSGKPGQQGPPGEVGP---RGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGL 407
            PG PG  G SG PG  G PGE GP    G  G PG  GE G  G  G+PG  G  G PG 
Sbjct: 1127 PGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQ 1186

Query: 408  PGL--PGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNP 465
            PG   PGPPGLPG+ G +G  G PG  G  G  G +GE G  G  G  G PGP GS G  
Sbjct: 1187 PGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPA 1246

Query: 466  -----GEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIK 520
                 G PG +GP G  GLPG EGP G PG  G++GE+G  G PG+ G PG         
Sbjct: 1247 LEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKG------ 1300

Query: 521  QVCMRVIQEHFAEMAASLKRPD-SGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIK 579
                    +    +  +  RP  +G  G PG PG PG PG  G +G PG  G  G PG+ 
Sbjct: 1301 -------DQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLI 1353

Query: 580  GPPGALGLRGPKGD-LGEKGERGPPG-------------RGPNGLPGAIGLPGDPG---- 621
            GPPG  GL GP G  +  KG+ GPPG             +GP GLPG  G PGDPG    
Sbjct: 1354 GPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGL 1413

Query: 622  PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
            P   G  GR G+ G PG  G  G+ GPPGP GL G
Sbjct: 1414 PGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQG 1448



 Score =  539 bits (1388), Expect = e-153
 Identities = 335/765 (43%), Positives = 382/765 (49%), Gaps = 162/765 (21%)

Query: 7    DRGALGLL----LLGLCLCAAQRGPPGEQGPPGPPG---------PPGVPGIDGIDGDRG 53
            D+G LG      L GL     Q G PG  GP G PG         PPG PG+ G+ G+ G
Sbjct: 559  DKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIG 618

Query: 54   PKGPPG--PPGPAGE---------PGKPGAPG-------------KPGTPGADGLTGPDG 89
            P GPPG  PPGP GE         PG+PG PG             KPG PG  G  G  G
Sbjct: 619  PMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVG 678

Query: 90   SPGSIGSKGQKGEPGVPGSRG---FPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGP 146
             PG  G  GQ G PG+PGS+G    PG G+PGPPGP G  G+PG  G  G  G  G  GP
Sbjct: 679  LPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGP 738

Query: 147  PGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGE 206
            PGPPG PGP+G  GF       P   PPG  G PG  G  G KG +G  G PG  G  G 
Sbjct: 739  PGPPGFPGPKGEPGF-----ALPG--PPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGL 791

Query: 207  EGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGP 266
            +G  G  G+VG  G PG  G  G+ GI G +G  G  G+ G  G  GL G PG++G  GP
Sbjct: 792  DGLPGPKGDVGPNGQPGPMGPPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGP 850

Query: 267  PG--EAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDA 324
            PG    GP G+RG+    GIPG PGP G  G PG+ G+ G  G PGTKGE G  GPPG  
Sbjct: 851  PGLDVPGPPGERGSP---GIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPP 907

Query: 325  GLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEV------------ 372
            G  G+PG  G+PG KG  G +G  G PG  G+ G+ G+PG  GPPG +            
Sbjct: 908  GPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKG 967

Query: 373  -----------GPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLP---GPPGLPG 418
                       GP+G QGLPG  G+ G  G PGLPG  G  G+PGLPG P   GPPGL G
Sbjct: 968  EPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKG 1027

Query: 419  MKGD------RGVVGEPGPKGEQGASGEEGEAGERGELGD--------IGLPGP------ 458
              GD      +GV G PGP G  G  G  G  G++G+ GD         GLPGP      
Sbjct: 1028 TIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGL 1087

Query: 459  ---------KGSAGNPGEPGLRGPEGSR---GLPGVEGPRGPPGPRGVQGEQGATGLPGV 506
                     KGS G+PG PGL G  G++   GLPG  G  GPPGP+G+ G  G  GLPG 
Sbjct: 1088 PGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGE 1147

Query: 507  QGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGF 566
             GP                                  G  G PG+PGPPG  G PG++G 
Sbjct: 1148 PGP---------------------------------VGGGGHPGQPGPPGEKGKPGQDGI 1174

Query: 567  PGQMGIRGLP-----GIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGL---- 616
            PG  G +G P     G  GPPG  GL G KGD G  G  G PG  GP G PG  G     
Sbjct: 1175 PGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQ 1234

Query: 617  -----PGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
                 PG PGPA  G  G  G +GPP   G PG+PGP GPPGLPG
Sbjct: 1235 GPPGPPGSPGPALEGPKGNPGPQGPP---GRPGLPGPEGPPGLPG 1276



 Score =  521 bits (1343), Expect = e-148
 Identities = 337/759 (44%), Positives = 383/759 (50%), Gaps = 136/759 (17%)

Query: 26  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 85
           G PG  G PGP GPPG  G  G DG  GP GP G  GP G PG PG PG PG PG DG  
Sbjct: 57  GHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAP 116

Query: 86  GPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRV------GPVG 139
           GP G PG  G+KG++G PG P   GFP  G+ GPPGPPG  G+ GE G +      GP G
Sbjct: 117 GPQGIPGCNGTKGERGFPGSP---GFP--GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKG 171

Query: 140 DPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHK--------GA 191
           +PG  GPPG  G PGP G  G     P+ P   PPG  G PG PG+ G K        G 
Sbjct: 172 NPGYPGPPGIQGLPGPTGIPG-----PIGPPG-PPGLMGPPGPPGLPGPKGNMGLNFQGP 225

Query: 192 KGEIGEPGRQGHKG----------------EEGDQGELGEVGAQGPPGAQGLRGITGIVG 235
           KGE GE G QG  G                ++GDQG  G+ G  GPPG +G  G  G  G
Sbjct: 226 KGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG--G 283

Query: 236 DKGEKGAR---------GLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPG 286
           +KGEKG +         G DGE G  G+PG PGD G  G PG  G KG +G  G  G PG
Sbjct: 284 EKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPG 343

Query: 287 LP----------GPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIP 336
           L           G KG+ GLPG+ G  G  G PG +G PG PGPPG A + G PG PG P
Sbjct: 344 LVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG-AAVMGPPGPPGFP 402

Query: 337 GAKGVAGEKGSTG--APGKPGQMGNSGKPGQQGPPGEVGPR----------GPQGLPGSR 384
           G +G  G++G  G   PG PG  G  G PG  GPPG  GP           GP G PGS 
Sbjct: 403 GERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSP 462

Query: 385 GELGPVGSPGLPGKLGSL-------------GSPGLPGLPGPP---GLPGMKGDRGVVGE 428
           G+ G  G  G+ G  G               G PGLPGLPGPP   G PG KG++G  G 
Sbjct: 463 GDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGA 522

Query: 429 PGPK---GEQGASGEEGEAGERGELGDI----GLPGPKGSAGNPGE---PGLRGPEGSRG 478
            GPK   G  GA G  G  G +GE GDI    G+ G KG  G+PG    PGL G  G  G
Sbjct: 523 TGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDG 582

Query: 479 LPGVEGPRGPP------GPRGVQGEQGATGLP---GVQGPPGRAPT----DQHIKQVCMR 525
           LPG+ GP+G P      G RG  G  G  GLP   G  GPPG  P     ++ I+ V   
Sbjct: 583 LPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGN 642

Query: 526 VIQEHF----AEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGP 581
             Q        +   ++ +P  G  GLPG PG  G  G PG+ G PGQ G+ G+PG KG 
Sbjct: 643 PGQPGIPGPKGDPGQTITQP--GKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGE 700

Query: 582 PG--ALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGV 639
           PG   +GL GP G  G  G  GPP  G  G PG IGL G PGP      G  G +G PG 
Sbjct: 701 PGIPGIGLPGPPGPKGFPGIPGPP--GAPGTPGRIGLEGPPGPP-----GFPGPKGEPGF 753

Query: 640 AGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPDP 678
           A    +PGPPGPPGLPGF          G R F   P P
Sbjct: 754 A----LPGPPGPPGLPGF---KGALGPKGDRGFPGPPGP 785



 Score =  518 bits (1333), Expect = e-147
 Identities = 336/804 (41%), Positives = 383/804 (47%), Gaps = 157/804 (19%)

Query: 4    TARDRGALGLLLLGLCLCAAQRGPPGEQGPPGPPGPPGV-----PGIDGIDGDRGPKGPP 58
            T  ++G +GL   GL     +RG PG QGPPG PGPPG      PG  G  G+RG KG  
Sbjct: 354  TIGEKGNIGLP--GLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDE 411

Query: 59   GPPG-----PAGEPGKPGAPGKPGTPGADGL----------TGPDGSPGSIGSKGQKGEP 103
            GPPG     P G  G+PGAPG PG PG  G            GP G PGS G KG +GE 
Sbjct: 412  GPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQ 471

Query: 104  GVPGSRGF-------------PGR-GIPGPPGPPGTAGLPGELGR------VGPVGDPGR 143
            GV G +G              PG+ G+PG PGPPG+ G PG+ G        GP G PG 
Sbjct: 472  GVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGI 531

Query: 144  RGPPGPPGPPGPRGTIGF------------HDGDPLCPNAC----PPGRSGYPGLPGMRG 187
             G PG PG PG +G  G               G P  P        PG+ G PGLPG +G
Sbjct: 532  PGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKG 591

Query: 188  HKGA---KGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARG 244
              G    KGE G PG  G  G  G+ G +G  G  GPPG  G +GI G+ G+ G+ G  G
Sbjct: 592  EPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQPGIPG 650

Query: 245  LDGEPGPQ-------------------GLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIP 285
              G+PG                     GLPG PG  GQ G PG  G KG+ G  G  G+P
Sbjct: 651  PKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI-GLP 709

Query: 286  GLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAG-----LQGLPGVPGIPGAKG 340
            G PGPKG  G+PG  G  G PG  G +G PG PG PG  G     L G PG PG+PG KG
Sbjct: 710  GPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKG 769

Query: 341  VAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGP--------------QGLPGSRGE 386
              G KG  G PG PG  G +G  G  GP G+VGP G               QG PG  G 
Sbjct: 770  ALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI 829

Query: 387  LGPVGSPGL-----------------PGKLGSLGSPGLPGLPGP---PGLPGMKGDRGVV 426
             GP+G PGL                 PG  G  GSPG+PG PGP   PG PG+ G  G  
Sbjct: 830  PGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS 889

Query: 427  GEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPR 486
            G PG KGE G  G  G  G  G  G  G+PG KG  G  G+PGL GP G +G  G  G  
Sbjct: 890  GFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLP 949

Query: 487  GPPGP--------RGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASL 538
            GPPGP        +G +GE G  G+PGV GP G                           
Sbjct: 950  GPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPG--------------------- 988

Query: 539  KRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKG 598
               D G  GL G+PG PGPPGP G  G PGQ G+ G PG+KG  G +G  GP+G  G  G
Sbjct: 989  ---DPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPG 1045

Query: 599  ERGPPGR-GPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPG---PPGPPGL 654
              G PG+ G  GLPG  G  GDPG +S G  G  G +G PG+ G PG PG     G PGL
Sbjct: 1046 PSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGL 1105

Query: 655  PGFCEPASCTMQAGQRAFNKGPDP 678
            PG         Q G   F   P P
Sbjct: 1106 PGLPGTPGAKGQPGLPGFPGTPGP 1129



 Score =  515 bits (1326), Expect = e-146
 Identities = 332/816 (40%), Positives = 388/816 (47%), Gaps = 195/816 (23%)

Query: 7    DRGALGLLLLGLCLCAAQRGPPGEQGP----------------PGPPGPPGVPGIDGIDG 50
            D G  G+ + G      Q G PG  GP                PGPPGPPG PG  G+ G
Sbjct: 410  DEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQG 469

Query: 51   DRGPK----------------GPPGPPGPAGEPGKPGA---------------------P 73
            ++G K                GPPG PG  G PG PG+                     P
Sbjct: 470  EQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLP 529

Query: 74   GKPGTPGADGLTGPDGSPGSI-------GSKGQKGEPGVPGSRGFPGR-------GIPGP 119
            G PG PGA G  G  G PG I       G KG+ G PG PG  G PG        G+PGP
Sbjct: 530  GIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGP 589

Query: 120  P------------GPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPL 167
                         GPPG  GLPG  G +GP+G PG  GPPGP G  G +G  G + G P 
Sbjct: 590  KGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG-FGPPGPVGEKGIQGVAG-NPGQPG 647

Query: 168  CP--------NACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELG--EVG 217
             P            PG+ G PG PG  G  G  G+ G PG+ G  G  G +GE G   +G
Sbjct: 648  IPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIG 707

Query: 218  AQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQG-----------LPGAPGDQGQRGP 266
              GPPG +G  GI G  G  G  G  GL+G PGP G           LPG PG  G  G 
Sbjct: 708  LPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGF 767

Query: 267  PGEAGPKGDRGAEGARGIP------GLPGPKGDT-------------------------- 294
             G  GPKGDRG  G  G P      GLPGPKGD                           
Sbjct: 768  KGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPP 827

Query: 295  GLPGVDGRDGIPGMPGTKGEPGK-----PGPPGDAGLQGLPGVP---GIPGAKGVAGEKG 346
            G+PG  G+ G+ G+PG KG+PG      PGPPG+ G  G+PG P   G PG+ G+ G+ G
Sbjct: 828  GIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAG 887

Query: 347  STGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPG 406
            ++G PG  G+MG  G P   GPPG +G  G  G+PG +G+ G  G PGLPG  G  GS G
Sbjct: 888  ASGFPGTKGEMGMMGPP---GPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKG 944

Query: 407  LPGLPGPPG-----LPGMKGDRGVVGEP------GPKGEQGASGEEGEAGERGELGDIGL 455
             PGLPGPPG     L G KG++G  G P      GPKG QG  G+ G+ G  G+ G  G 
Sbjct: 945  EPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGP 1004

Query: 456  PGPKGSAGNPGEPGLRGPEGSR------GLPGVEGPRGPPGPRGVQGEQGATGLPGVQGP 509
            PGPKG+ G PG+PGL GP G +      G PG +G  GPPGP GV G+ G+ GLPG +G 
Sbjct: 1005 PGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGD 1064

Query: 510  PGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQ 569
             G                             P   + GLPG PGP G PG PG  G PG 
Sbjct: 1065 KG----------------------------DPGISSIGLPGLPGPKGEPGLPGYPGNPGI 1096

Query: 570  MGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGPAS---- 624
             G  G PG+ G PG  G +G  G  G  G  GPPG +G +G PG  GLPG+PGP      
Sbjct: 1097 KGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGH 1156

Query: 625  YGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEP 660
             G+ G  GE+G PG  GIPG  G  G PG PGF  P
Sbjct: 1157 PGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNP 1192



 Score =  510 bits (1314), Expect = e-144
 Identities = 314/730 (43%), Positives = 367/730 (50%), Gaps = 125/730 (17%)

Query: 24   QRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGP----------PGPAGEPGKPGAP 73
            Q+G  G+ G  GP G PG+PG  G  G  G KG PG            G  G PG PG P
Sbjct: 513  QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572

Query: 74   GKPGTPGADGLTG---PDGSPGSIGSKGQKGEPGVPGSRGFPGRGIP------GPPGP-- 122
            G PGTPG DGL G   P G PG I  KG++G PG PG  G PG   P      GPPGP  
Sbjct: 573  GLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVG 632

Query: 123  ----PGTAGLPGELGRVGPVGDPGRR----GPPGPPGPPGPRGTIGFHDGDPLCPNAC-- 172
                 G AG PG+ G  GP GDPG+     G PG PG PG  G +G   GDP  P     
Sbjct: 633  EKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGL-PGDPGLPGQPGL 691

Query: 173  -------------------PPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGEL 213
                               PPG  G+PG+PG  G  G  G IG  G  G  G  G +GE 
Sbjct: 692  PGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEP 751

Query: 214  GEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPK 273
            G     GPPG  GL G  G +G KG++G  G  G PG  GL G PG +G  GP G+ GP 
Sbjct: 752  G-FALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPM 810

Query: 274  GDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPG-----PPGDAGLQG 328
            G  G  G     G+ GP G  G+PG  G+ G+ G+PG KG+PG PG     PPG+ G  G
Sbjct: 811  GPPGLPGI----GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPG 866

Query: 329  LPGVPGI---PGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRG 385
            +PG PG    PG+ G+ G+ G++G PG  G+MG  G PG   PPG +G  G  G+PG +G
Sbjct: 867  IPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPG---PPGPLGIPGRSGVPGLKG 923

Query: 386  ELGPVGSPGLPGKLGSLGSPGLPGLPGPPG-----LPGMKGDRGVVGEPG------PKGE 434
            + G  G PGLPG  G  GS G PGLPGPPG     L G KG++G  G PG      PKG 
Sbjct: 924  DDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGY 983

Query: 435  QGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRG------LPGVEGPRGP 488
            QG  G+ G+ G  G+ G  G PGPKG+ G PG+PGL GP G +G       PG +G  GP
Sbjct: 984  QGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGP 1043

Query: 489  PGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGL 548
            PGP GV G+ G+ GLPG +G  G                             P   + GL
Sbjct: 1044 PGPSGVPGQPGSPGLPGQKGDKGD----------------------------PGISSIGL 1075

Query: 549  PGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGP 607
            PG PGP G PG PG  G PG  G  G PG+ G PG  G +G  G  G  G  GPPG +G 
Sbjct: 1076 PGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGI 1135

Query: 608  NGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQA 667
            +G PG  GLPG+PGP   G           G  G PG PG  G PG  G   PA    + 
Sbjct: 1136 SGPPGNPGLPGEPGPVGGG-----------GHPGQPGPPGEKGKPGQDGIPGPAGQKGEP 1184

Query: 668  GQRAF-NKGP 676
            GQ  F N GP
Sbjct: 1185 GQPGFGNPGP 1194



 Score =  506 bits (1302), Expect = e-143
 Identities = 328/811 (40%), Positives = 378/811 (46%), Gaps = 190/811 (23%)

Query: 24  QRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADG 83
           +RG PG  G PG  GPPG PGI G+ G+ G       PGP G PG PG PG  G PG  G
Sbjct: 130 ERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTG 189

Query: 84  LTGPDGSPGSIGSKGQKGEPGVPGSRGFPG------------RGIPGPPGPP-------- 123
           + GP G PG  G  G  G PG+PG +G  G            +G+ GPPGPP        
Sbjct: 190 IPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKR 249

Query: 124 --------GTAGLPGELGRVGPVGDPGRRGPPGPP----------GPPGPRGTIG--FHD 163
                   G  GLPG+    GP G PG RGPPGPP          G PG RG  G    +
Sbjct: 250 PIDVEFQKGDQGLPGDR---GPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGEN 306

Query: 164 GDPLCPNACPPGRSGYPGLPGMRGHKGAKGE-------------------------IGEP 198
           G P  P    PG  GYPG PG  G KG KG+                         IG P
Sbjct: 307 GQPGIPGL--PGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLP 364

Query: 199 GRQGHKGEEGDQGELGEVGAQGPPGA--QGLRGITGIVGDKGEKGAR-----------GL 245
           G  G KGE G  G  G  G  GPPGA   G  G  G  G++G+KG             GL
Sbjct: 365 GLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGL 424

Query: 246 DGEPGPQGLPGAPGDQG----------QRGPPGEAGPKGDRGAEGARGI----------- 284
           DG+PG  GLPG PG  G          + GPPG  G  GD+G +G +G+           
Sbjct: 425 DGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNC 484

Query: 285 --PGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPG----- 337
              G+ GP G  GLPG+ G  G  G PG KGE G+ G  G  GL G+PG PG PG     
Sbjct: 485 IGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSK 544

Query: 338 --------AKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGP 389
                     G+ G+KG  G+PG PG  G  G PGQ G PG  GP+G  G    +GE GP
Sbjct: 545 GEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGP 604

Query: 390 VGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGE------PGPKGEQGAS----G 439
            G+PGLPG  G++G  G PG  GPPG  G KG +GV G       PGPKG+ G +    G
Sbjct: 605 PGNPGLPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPG 663

Query: 440 EEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQG 499
           + G  G  G  GD+GLPG  G  G PG PG+ G +G  G+PG+ G  GPPGP+       
Sbjct: 664 KPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI-GLPGPPGPK------- 715

Query: 500 ATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPG--------R 551
             G PG+ GPPG   T   I                  L+ P  G  G PG         
Sbjct: 716 --GFPGIPGPPGAPGTPGRI-----------------GLEGP-PGPPGFPGPKGEPGFAL 755

Query: 552 PGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGAL---GLRGPKGDLGEKGERGPPG---- 604
           PGPPGPPG PG  G  G  G RG PG  GPPG     GL GPKGD+G  G+ GP G    
Sbjct: 756 PGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGL 815

Query: 605 --------RGPNGLPGAIGLP---------GDPGPASYGRNGRDGERGPPGVAGIPGVPG 647
                    GP G+PG IG P         GDPGP      G  GERG PG+ G PG  G
Sbjct: 816 PGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIG 875

Query: 648 PPGPPGLPGFCEPASCTMQAGQRAFNKGPDP 678
           PPG PGLPG    +      G+      P P
Sbjct: 876 PPGSPGLPGKAGASGFPGTKGEMGMMGPPGP 906



 Score =  496 bits (1276), Expect = e-140
 Identities = 329/786 (41%), Positives = 376/786 (47%), Gaps = 162/786 (20%)

Query: 26  GPPGEQGPPGPPGPPGVPGIDGID--------GDRGPKGPPGPPGPAGEPGKP------- 70
           GPPG  GPPGPPG PG  G  G++        G++G +GPPGPPG   E  +P       
Sbjct: 198 GPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQK 257

Query: 71  ---GAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR----GIPGPPGPP 123
              G PG  G PG  G+ GP G PG  G KG+KGE G PG RG PG+    G PG PG P
Sbjct: 258 GDQGLPGDRGPPGPPGIRGPPGPPG--GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLP 315

Query: 124 GTAGLPGELGRVGPVGDPGRRGPPGPPGP----------------------PGPRGTIGF 161
           G  G PGE GR G  G  G  GPPGPPG                       PG +G  GF
Sbjct: 316 GDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGF 375

Query: 162 HD-----GDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIG-----------EPGRQGHKG 205
                  G P  P A   G  G PG PG RG KG +G  G           +PG  G  G
Sbjct: 376 PGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPG 435

Query: 206 EEGDQG-------ELGEVGAQGPPGAQGLRGITGIVGDKGEKG-------ARGLDGEPGP 251
             G  G       E+ E G  GPPG+ G +G+ G  G KG+KG         G+ G PG 
Sbjct: 436 PPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495

Query: 252 QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDG----IPG 307
            GLPG PG  G  G PG+ G KG  GA G +G+PG+PG  G  G PG  G  G     PG
Sbjct: 496 PGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG 555

Query: 308 MPGTKGEPGKPGPPGDAGLQGLPG---VPGIPGAKG------VAGEKGSTGAPGKPGQMG 358
           M G KGE G PG PG  GL G PG   +PG+PG KG        GE+G  G PG PG  G
Sbjct: 556 MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPG 615

Query: 359 NSGKPGQQG--PPGEVGPRGPQG---------LPGSRGELGPV----GSPGLPGK----- 398
           N G  G  G  PPG VG +G QG         +PG +G+ G      G PGLPG      
Sbjct: 616 NIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDG 675

Query: 399 -LGSLGSPGLPGLPGPPGLPGMKGDRGV--VGEPGPKGEQGASGEEGEAGERGELGDIGL 455
            +G  G PGLPG PG PG+PG KG+ G+  +G PGP G +G  G  G  G  G  G IGL
Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGL 735

Query: 456 PGPKGSAGNPGEPGLRGPEGSRG--LPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRA 513
            GP      PG PG  GP+G  G  LPG  GP G PG +G  G +G  G PG  GPPGR 
Sbjct: 736 EGP------PGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRT 789

Query: 514 PTDQHIKQVCMRVIQEHFAEMAASLKRP--DSGATGLPGRPGPPG--------PPGPPGE 563
             D                     L  P  D G  G PG  GPPG        PPGPPG 
Sbjct: 790 GLD--------------------GLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI 829

Query: 564 NGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR-GPNGLPGAIGLPGDPG- 621
            G  GQ G+ G+PG KG PG  GL  P G  GE+G  G PG  GP G PG+ GLPG  G 
Sbjct: 830 PGPIGQPGLHGIPGEKGDPGPPGLDVP-GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGA 888

Query: 622 ---PASYGRNGRDGERGPPGV------AGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAF 672
              P + G  G  G  GPPG       +G+PG+ G  G  G PG   P       G+   
Sbjct: 889 SGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGL 948

Query: 673 NKGPDP 678
              P P
Sbjct: 949 PGPPGP 954



 Score =  457 bits (1177), Expect = e-128
 Identities = 275/631 (43%), Positives = 322/631 (51%), Gaps = 115/631 (18%)

Query: 24   QRGPPGEQGPPGPPGPPGVPGIDG---------IDGDRGPKGPPGPPGPAGEPGKPGAPG 74
            +RG PG  G PGP GPPG PG+ G           G+ G  GPPGPPGP G PG+ G PG
Sbjct: 861  ERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPG 920

Query: 75   ---------KPGTPGADGLTGPDGSPGS-----------IGSKGQKGEPGVPGSRGFPG- 113
                     +PG PG  G  G  G PG            +GSKG+KGEPG+PG  G  G 
Sbjct: 921  LKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGP 980

Query: 114  ---RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFH-------- 162
               +G+PG PG PG +G PG  G  GP G+PG  G PG  GPPG +GTIG          
Sbjct: 981  KGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGV 1040

Query: 163  DGDPLCPNACPPGRSGYPGLPGMRGHKG--------------AKGEIGEPGRQGHKGEEG 208
            +G P  P+  P G+ G PGLPG +G KG               KGE G PG  G+ G +G
Sbjct: 1041 EGPP-GPSGVP-GQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKG 1098

Query: 209  DQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPG 268
              G+ G  G  G PGA+G  G+ G  G  G  G +G+ G PG  GLPG PG  G  G PG
Sbjct: 1099 SVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPG 1158

Query: 269  EAGPKGDRGAEGARGIPGLPGPKGDTGLPGVD--GRDGIPGMPGTKGEPGKPGPPGDAGL 326
            + GP G++G  G  GIPG  G KG+ G PG    G  G+PG+ G KG+ G PG PG+ GL
Sbjct: 1159 QPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGL 1218

Query: 327  QGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVG---PRGPQGLPGS 383
             G  G PG  G  GV G  G  G+PG P   G  G PG QGPPG  G   P GP GLPG+
Sbjct: 1219 PGPKGEPGFHGFPGVQGPPGPPGSPG-PALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGN 1277

Query: 384  ------RGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPG------P 431
                  +G  G  G PGLPG  G  G PGL G PG PGL GMKGD G+ G PG      P
Sbjct: 1278 GGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGP 1337

Query: 432  KGEQGASGEEGEAGERGELGDIGLPGPKGSA----GNPGEPGLRGPEGSRGLPGVEGPRG 487
             G  G++G EGE G  G  G  GLPGP G +    G+ G PG+ G  G +GLPG +GP+G
Sbjct: 1338 SGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQG 1397

Query: 488  PPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATG 547
             PGP G  G+ G  GLPG  G  GR                               G  G
Sbjct: 1398 LPGPTGPPGDPGRNGLPGFDGAGGR------------------------------KGDPG 1427

Query: 548  LPGRP------GPPGPPGPPGENGFPGQMGI 572
            LPG+P      GPPGP G  G  G PG   +
Sbjct: 1428 LPGQPGTRGLDGPPGPDGLQGPPGPPGTSSV 1458



 Score =  457 bits (1175), Expect = e-128
 Identities = 279/640 (43%), Positives = 326/640 (50%), Gaps = 124/640 (19%)

Query: 26   GPPGEQGPPG---PPGP------PGVP------GIDGIDGDRGPKGPPGPPGPAGEPGKP 70
            GPPGE+G PG    PGP      PG+P      G  G  G+ G  GPPGPPGP G PG+ 
Sbjct: 857  GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRS 916

Query: 71   GAP---------GKPGTPGADGLTGPDGSPG-----------SIGSKGQKGEPGVPGSRG 110
            G P         G+PG PG  G  G  G PG            +GSKG+KGEPG+PG  G
Sbjct: 917  GVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPG 976

Query: 111  FPG----RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFH---- 162
              G    +G+PG PG PG +G PG  G  GP G+PG  G PG  GPPG +GTIG      
Sbjct: 977  VSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPG 1036

Query: 163  ----DGDPLCPNACPPGRSGYPGLPGMRGHK--------------GAKGEIGEPGRQGHK 204
                +G P  P+   PG+ G PGLPG +G K              G KGE G PG  G+ 
Sbjct: 1037 PQGVEGPP-GPSGV-PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNP 1094

Query: 205  GEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQR 264
            G +G  G+ G  G  G PGA+G  G+ G  G  G  G +G+ G PG  GLPG PG  G  
Sbjct: 1095 GIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGG 1154

Query: 265  GPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGV--DGRDGIPGMPGTKGEPGKPGPPG 322
            G PG+ GP G++G  G  GIPG  G KG+ G PG    G  G+PG+ G KG+ G PG PG
Sbjct: 1155 GHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPG 1214

Query: 323  DAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGE---VGPRGPQG 379
            + GL G  G PG  G  GV G  G  G+PG P   G  G PG QGPPG     GP GP G
Sbjct: 1215 NPGLPGPKGEPGFHGFPGVQGPPGPPGSPG-PALEGPKGNPGPQGPPGRPGLPGPEGPPG 1273

Query: 380  LPGS------RGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEP---- 429
            LPG+      +G  G  G PGLPG  G  G PGL G PG PGL GMKGD G+ G P    
Sbjct: 1274 LPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPG 1333

Query: 430  --GPKGEQGASGEEGEAGERGELGDIGLPGPKGSA----GNPGEPGLRGPEGSRGLPGVE 483
              GP G  G++G EGE G  G  G  GLPGP G +    G+ G PG+ G  G +GLPG +
Sbjct: 1334 MKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQ 1393

Query: 484  GPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDS 543
            GP+G PGP G  G+ G  GLPG  G  GR                               
Sbjct: 1394 GPQGLPGPTGPPGDPGRNGLPGFDGAGGR------------------------------K 1423

Query: 544  GATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPG 583
            G  GLPG+PG  G  GPPG +         GL G  GPPG
Sbjct: 1424 GDPGLPGQPGTRGLDGPPGPD---------GLQGPPGPPG 1454



 Score =  426 bits (1096), Expect = e-119
 Identities = 278/656 (42%), Positives = 312/656 (47%), Gaps = 145/656 (22%)

Query: 90  SPGS----IGSKGQKGEPGVPGSRGFPGR-GIPGPPGPPGTAGLPGELGRVGPVGDPGRR 144
           SPGS     G KG+KGE G PG  G PG  G PGP GPPG  G  G+ G  GP G  G R
Sbjct: 33  SPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIR 92

Query: 145 GPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHK 204
           GPPG PG PG                         PGLPGM GH GA G  G PG  G K
Sbjct: 93  GPPGLPGFPGT------------------------PGLPGMPGHDGAPGPQGIPGCNGTK 128

Query: 205 GEEGDQGELGEVGAQGPPGAQGLRGITGIVGD------KGEKGARGLDGEPGPQGLPGAP 258
           GE G  G  G  G QGPPG  G+ G+ G  G        G KG  G  G PG QGLPG  
Sbjct: 129 GERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPT 188

Query: 259 GDQGQRGPPGE-----------------------AGPKGDRGAEGARGIPGLPG------ 289
           G  G  GPPG                         GPKG++G +G +G PG PG      
Sbjct: 189 GIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQK 248

Query: 290 -------PKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVA 342
                   KGD GLPG  G  G PG+ G  G PG  G  G+ G QG PG  G PG  G  
Sbjct: 249 RPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG--GEKGEKGEQGEPGKRGKPGKDGEN 306

Query: 343 GEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGL----PGSRGELGPVGSPGLPGK 398
           G+ G  G PG PG  G  G+ G++G  G+ GP GP GL    PG+   +G  G+ GLPG 
Sbjct: 307 GQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGL 366

Query: 399 LGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGP 458
            G  G  G PG+ GPPGLPG  G   V+G PGP G  G  G++G+ G  G    I +PGP
Sbjct: 367 PGEKGERGFPGIQGPPGLPGPPG-AAVMGPPGPPGFPGERGQKGDEGPPG----ISIPGP 421

Query: 459 KGSAGNPGEPGLRGPEGSRG----------LPGVEGPRGPPGPRGVQGEQGATGLPGVQG 508
            G  G PG PGL GP G  G           PG  GP G PG +G+QGEQG  G  G   
Sbjct: 422 PGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKG--- 478

Query: 509 PPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPG 568
                         C   I               +G +G PG+PG PG PGPPG  GFPG
Sbjct: 479 ------------DTCFNCI--------------GTGISGPPGQPGLPGLPGPPGSLGFPG 512

Query: 569 Q---------MGIRGLPGIKGPPGALGLRGPKGD----------LGEKGERGPPGR---- 605
           Q          G +GLPGI G PGA G  G KG+           G+KGE G PG     
Sbjct: 513 QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572

Query: 606 GPNGLPGAIGLPGDPGP-ASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEP 660
           G  G PG  GLPG PGP    G     GERGPPG  G+PG+PG  GP G PGF  P
Sbjct: 573 GLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPP 628



 Score =  283 bits (723), Expect = 5e-76
 Identities = 163/357 (45%), Positives = 186/357 (52%), Gaps = 44/357 (12%)

Query: 15   LLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPG 74
            L GL      +G PG  G PG PGPPG  GI G  G+ G  G PGP G  G PG+PG PG
Sbjct: 1105 LPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164

Query: 75   KPGTPGADGLTGPDGS-----------------PGSIGSKGQKGEPGVPGSRGFPG---- 113
            + G PG DG+ GP G                  PG  G KG  G PG+PG+ G PG    
Sbjct: 1165 EKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGE 1224

Query: 114  ---RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPN 170
                G PG  GPPG  G PG     GP G+PG +GPPG PG PGP G  G      L  N
Sbjct: 1225 PGFHGFPGVQGPPGPPGSPGP-ALEGPKGNPGPQGPPGRPGLPGPEGPPG------LPGN 1277

Query: 171  ACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGI 230
                G  G PG PG+ G  G KG+ G PG QG+ G  G  G  G+ G  G PG  G++G 
Sbjct: 1278 GGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGP 1337

Query: 231  TGIVGDKGEKGARGLDGEPGPQGLPGAPG-------DQGQRGPPGEAGPKGDRGAEGARG 283
            +G+ G  G +G  GL G PGP GLPG  G       D G  G PG+ G KG  G +G +G
Sbjct: 1338 SGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQG 1397

Query: 284  IPGLPGPKGD---TGLPGVD---GRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPG 334
            +PG  GP GD    GLPG D   GR G PG+PG  G  G  GPPG  GLQG PG PG
Sbjct: 1398 LPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1454


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score =  558 bits (1439), Expect = e-159
 Identities = 332/719 (46%), Positives = 380/719 (52%), Gaps = 112/719 (15%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPG-----PPGPAGEPGKPGAPGKPGTPG 80
            G  G+ G PG PG PG PG+ GI G +G  G PG     PPGP G PG PG PG PGTPG
Sbjct: 672  GRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPG 731

Query: 81   ADGLTGPDGSPGSIGSKGQKGE--PGVPGSRGFPG----------RGIPGPPGPPGTAGL 128
              GL GP G PG  G KG+ G   PG PG  G PG          RG PGPPGPPG  GL
Sbjct: 732  RIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGL 791

Query: 129  ---PGELGRVGPVGDPGR-----------RGPPGPPGPPGPRGTIGFHD-----GDPLCP 169
               PG  G VGP G PG            +GPPGPPG PGP G  G H      GDP  P
Sbjct: 792  DGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPP 851

Query: 170  NAC---PPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQG 226
                  PPG  G PG+PG  G  G  G  G PG+ G  G  G +GE+G +G  GPPG  G
Sbjct: 852  GLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLG 911

Query: 227  LRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGP-----KGDRGAEGA 281
            + G +G+ G KG+ G +G  G PGP G  G+ G+ G  GPPG   P     KG++G  G 
Sbjct: 912  IPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGL 971

Query: 282  RGIPGLPGPKG------DTGLPGVDGRDGIPGMPGTKGEPGKPGPPG------------D 323
             GIPG+ GPKG      D G PG+ G+ G+PG PG KG PG PG PG            D
Sbjct: 972  PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGD 1031

Query: 324  AGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSG-----KPGQQGPPGEVGPRGPQ 378
             G  G  GV G PG  GV G+ GS G PG+ G  G+ G      PG  GP GE G  G  
Sbjct: 1032 MGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYP 1091

Query: 379  GLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKG------DRGVVGEPGPK 432
            G PG +G +G  G PGLPG  G+ G PGLPG PG PG PG KG      + G+ GEPGP 
Sbjct: 1092 GNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPV 1151

Query: 433  GEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPG-----------LRGPEGSRGLPG 481
            G  G  G+ G  GE+G+ G  G+PGP G  G PG+PG           L G +G  GLPG
Sbjct: 1152 GGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPG 1211

Query: 482  VEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRP 541
            + G  G PGP+G   E G  G PGVQGPPG   +                     +L+ P
Sbjct: 1212 IPGNPGLPGPKG---EPGFHGFPGVQGPPGPPGSP------------------GPALEGP 1250

Query: 542  --DSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGE 599
              + G  G PGRPG  G PGP G  G PG  GI+G  G  G PG  GL G KGD G  G 
Sbjct: 1251 KGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGL 1310

Query: 600  RGPPGR-GPNGLPGAIGLPGDPG-PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
            +G PGR G NG+ G  GLPG PG P   G +G  G  GP G    PG+ GPPGPPGLPG
Sbjct: 1311 QGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGE---PGLIGPPGPPGLPG 1366



 Score =  543 bits (1399), Expect = e-154
 Identities = 335/765 (43%), Positives = 382/765 (49%), Gaps = 159/765 (20%)

Query: 7    DRGALGLL----LLGLCLCAAQRGPPGEQGPPGPPG---------PPGVPGIDGIDGDRG 53
            D+G LG      L GL     Q G PG  GP G PG         PPG PG+ G+ G+ G
Sbjct: 559  DKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIG 618

Query: 54   PKGPPG--PPGPAGE---------PGKPGAPG-------------KPGTPGADGLTGPDG 89
            P GPPG  PPGP GE         PG+PG PG             KPG PG  G  G  G
Sbjct: 619  PMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVG 678

Query: 90   SPGSIGSKGQKGEPGVPGSRG---FPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGP 146
             PG  G  GQ G PG+PGS+G    PG G+PGPPGP G  G+PG  G  G  G  G  GP
Sbjct: 679  LPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGP 738

Query: 147  PGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGE 206
            PGPPG PGP+G  GF       P   PPG  G PG  G  G KG +G  G PG  G  G 
Sbjct: 739  PGPPGFPGPKGEPGF-----ALPG--PPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGL 791

Query: 207  EGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGP 266
            +G  G  G+VG  G PG  G  G+ GI G +G  G  G+ G  G  GL G PG++G  GP
Sbjct: 792  DGLPGPKGDVGPNGQPGPMGPPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGP 850

Query: 267  PG--EAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDA 324
            PG    GP G+RG+    GIPG PGP G  G PG+ G+ G  G PGTKGE G  GPPG  
Sbjct: 851  PGLDVPGPPGERGSP---GIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPP 907

Query: 325  GLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEV------------ 372
            G  G+PG  G+PG KG  G +G  G PG  G+ G+ G+PG  GPPG +            
Sbjct: 908  GPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKG 967

Query: 373  -----------GPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLP---GPPGLPG 418
                       GP+G QGLPG  G+ G  G PGLPG  G  G+PGLPG P   GPPGL G
Sbjct: 968  EPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKG 1027

Query: 419  MKGD------RGVVGEPGPKGEQGASGEEGEAGERGELGD--------IGLPGP------ 458
              GD      +GV G PGP G  G  G  G  G++G+ GD         GLPGP      
Sbjct: 1028 TIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGL 1087

Query: 459  ---------KGSAGNPGEPGLRGPEGSR---GLPGVEGPRGPPGPRGVQGEQGATGLPGV 506
                     KGS G+PG PGL G  G++   GLPG  G  GPPGP+G+ G  G  GLPG 
Sbjct: 1088 PGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGE 1147

Query: 507  QGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGF 566
             GP                                  G  G PG+PGPPG  G PG++G 
Sbjct: 1148 PGP---------------------------------VGGGGHPGQPGPPGEKGKPGQDGI 1174

Query: 567  PGQMGIRGLP-----GIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGL---- 616
            PG  G +G P     G  GPPG  GL G KGD G  G  G PG  GP G PG  G     
Sbjct: 1175 PGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQ 1234

Query: 617  -----PGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
                 PG PGPA  G  G  G +GPPG  G  G+PGP GPPGLPG
Sbjct: 1235 GPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPG 1279



 Score =  521 bits (1343), Expect = e-148
 Identities = 337/759 (44%), Positives = 383/759 (50%), Gaps = 136/759 (17%)

Query: 26  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 85
           G PG  G PGP GPPG  G  G DG  GP GP G  GP G PG PG PG PG PG DG  
Sbjct: 57  GHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAP 116

Query: 86  GPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRV------GPVG 139
           GP G PG  G+KG++G PG P   GFP  G+ GPPGPPG  G+ GE G +      GP G
Sbjct: 117 GPQGIPGCNGTKGERGFPGSP---GFP--GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKG 171

Query: 140 DPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHK--------GA 191
           +PG  GPPG  G PGP G  G     P+ P   PPG  G PG PG+ G K        G 
Sbjct: 172 NPGYPGPPGIQGLPGPTGIPG-----PIGPPG-PPGLMGPPGPPGLPGPKGNMGLNFQGP 225

Query: 192 KGEIGEPGRQGHKG----------------EEGDQGELGEVGAQGPPGAQGLRGITGIVG 235
           KGE GE G QG  G                ++GDQG  G+ G  GPPG +G  G  G  G
Sbjct: 226 KGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG--G 283

Query: 236 DKGEKGAR---------GLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPG 286
           +KGEKG +         G DGE G  G+PG PGD G  G PG  G KG +G  G  G PG
Sbjct: 284 EKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPG 343

Query: 287 LP----------GPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIP 336
           L           G KG+ GLPG+ G  G  G PG +G PG PGPPG A + G PG PG P
Sbjct: 344 LVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG-AAVMGPPGPPGFP 402

Query: 337 GAKGVAGEKGSTG--APGKPGQMGNSGKPGQQGPPGEVGPR----------GPQGLPGSR 384
           G +G  G++G  G   PG PG  G  G PG  GPPG  GP           GP G PGS 
Sbjct: 403 GERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSP 462

Query: 385 GELGPVGSPGLPGKLGSL-------------GSPGLPGLPGPP---GLPGMKGDRGVVGE 428
           G+ G  G  G+ G  G               G PGLPGLPGPP   G PG KG++G  G 
Sbjct: 463 GDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGA 522

Query: 429 PGPK---GEQGASGEEGEAGERGELGDI----GLPGPKGSAGNPGE---PGLRGPEGSRG 478
            GPK   G  GA G  G  G +GE GDI    G+ G KG  G+PG    PGL G  G  G
Sbjct: 523 TGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDG 582

Query: 479 LPGVEGPRGPP------GPRGVQGEQGATGLP---GVQGPPGRAPT----DQHIKQVCMR 525
           LPG+ GP+G P      G RG  G  G  GLP   G  GPPG  P     ++ I+ V   
Sbjct: 583 LPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGN 642

Query: 526 VIQEHF----AEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGP 581
             Q        +   ++ +P  G  GLPG PG  G  G PG+ G PGQ G+ G+PG KG 
Sbjct: 643 PGQPGIPGPKGDPGQTITQP--GKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGE 700

Query: 582 PG--ALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGV 639
           PG   +GL GP G  G  G  GPP  G  G PG IGL G PGP      G  G +G PG 
Sbjct: 701 PGIPGIGLPGPPGPKGFPGIPGPP--GAPGTPGRIGLEGPPGPP-----GFPGPKGEPGF 753

Query: 640 AGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPDP 678
           A    +PGPPGPPGLPGF          G R F   P P
Sbjct: 754 A----LPGPPGPPGLPGF---KGALGPKGDRGFPGPPGP 785



 Score =  518 bits (1333), Expect = e-147
 Identities = 336/804 (41%), Positives = 383/804 (47%), Gaps = 157/804 (19%)

Query: 4    TARDRGALGLLLLGLCLCAAQRGPPGEQGPPGPPGPPGV-----PGIDGIDGDRGPKGPP 58
            T  ++G +GL   GL     +RG PG QGPPG PGPPG      PG  G  G+RG KG  
Sbjct: 354  TIGEKGNIGLP--GLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDE 411

Query: 59   GPPG-----PAGEPGKPGAPGKPGTPGADGL----------TGPDGSPGSIGSKGQKGEP 103
            GPPG     P G  G+PGAPG PG PG  G            GP G PGS G KG +GE 
Sbjct: 412  GPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQ 471

Query: 104  GVPGSRGF-------------PGR-GIPGPPGPPGTAGLPGELGR------VGPVGDPGR 143
            GV G +G              PG+ G+PG PGPPG+ G PG+ G        GP G PG 
Sbjct: 472  GVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGI 531

Query: 144  RGPPGPPGPPGPRGTIGF------------HDGDPLCPNAC----PPGRSGYPGLPGMRG 187
             G PG PG PG +G  G               G P  P        PG+ G PGLPG +G
Sbjct: 532  PGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKG 591

Query: 188  HKGA---KGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARG 244
              G    KGE G PG  G  G  G+ G +G  G  GPPG  G +GI G+ G+ G+ G  G
Sbjct: 592  EPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQPGIPG 650

Query: 245  LDGEPGPQ-------------------GLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIP 285
              G+PG                     GLPG PG  GQ G PG  G KG+ G  G  G+P
Sbjct: 651  PKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI-GLP 709

Query: 286  GLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAG-----LQGLPGVPGIPGAKG 340
            G PGPKG  G+PG  G  G PG  G +G PG PG PG  G     L G PG PG+PG KG
Sbjct: 710  GPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKG 769

Query: 341  VAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGP--------------QGLPGSRGE 386
              G KG  G PG PG  G +G  G  GP G+VGP G               QG PG  G 
Sbjct: 770  ALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI 829

Query: 387  LGPVGSPGL-----------------PGKLGSLGSPGLPGLPGP---PGLPGMKGDRGVV 426
             GP+G PGL                 PG  G  GSPG+PG PGP   PG PG+ G  G  
Sbjct: 830  PGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS 889

Query: 427  GEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPR 486
            G PG KGE G  G  G  G  G  G  G+PG KG  G  G+PGL GP G +G  G  G  
Sbjct: 890  GFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLP 949

Query: 487  GPPGP--------RGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASL 538
            GPPGP        +G +GE G  G+PGV GP G                           
Sbjct: 950  GPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPG--------------------- 988

Query: 539  KRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKG 598
               D G  GL G+PG PGPPGP G  G PGQ G+ G PG+KG  G +G  GP+G  G  G
Sbjct: 989  ---DPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPG 1045

Query: 599  ERGPPGR-GPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPG---PPGPPGL 654
              G PG+ G  GLPG  G  GDPG +S G  G  G +G PG+ G PG PG     G PGL
Sbjct: 1046 PSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGL 1105

Query: 655  PGFCEPASCTMQAGQRAFNKGPDP 678
            PG         Q G   F   P P
Sbjct: 1106 PGLPGTPGAKGQPGLPGFPGTPGP 1129



 Score =  515 bits (1326), Expect = e-146
 Identities = 332/816 (40%), Positives = 388/816 (47%), Gaps = 195/816 (23%)

Query: 7    DRGALGLLLLGLCLCAAQRGPPGEQGP----------------PGPPGPPGVPGIDGIDG 50
            D G  G+ + G      Q G PG  GP                PGPPGPPG PG  G+ G
Sbjct: 410  DEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQG 469

Query: 51   DRGPK----------------GPPGPPGPAGEPGKPGA---------------------P 73
            ++G K                GPPG PG  G PG PG+                     P
Sbjct: 470  EQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLP 529

Query: 74   GKPGTPGADGLTGPDGSPGSI-------GSKGQKGEPGVPGSRGFPGR-------GIPGP 119
            G PG PGA G  G  G PG I       G KG+ G PG PG  G PG        G+PGP
Sbjct: 530  GIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGP 589

Query: 120  P------------GPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPL 167
                         GPPG  GLPG  G +GP+G PG  GPPGP G  G +G  G + G P 
Sbjct: 590  KGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG-FGPPGPVGEKGIQGVAG-NPGQPG 647

Query: 168  CP--------NACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELG--EVG 217
             P            PG+ G PG PG  G  G  G+ G PG+ G  G  G +GE G   +G
Sbjct: 648  IPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIG 707

Query: 218  AQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQG-----------LPGAPGDQGQRGP 266
              GPPG +G  GI G  G  G  G  GL+G PGP G           LPG PG  G  G 
Sbjct: 708  LPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGF 767

Query: 267  PGEAGPKGDRGAEGARGIP------GLPGPKGDT-------------------------- 294
             G  GPKGDRG  G  G P      GLPGPKGD                           
Sbjct: 768  KGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPP 827

Query: 295  GLPGVDGRDGIPGMPGTKGEPGK-----PGPPGDAGLQGLPGVP---GIPGAKGVAGEKG 346
            G+PG  G+ G+ G+PG KG+PG      PGPPG+ G  G+PG P   G PG+ G+ G+ G
Sbjct: 828  GIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAG 887

Query: 347  STGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPG 406
            ++G PG  G+MG  G P   GPPG +G  G  G+PG +G+ G  G PGLPG  G  GS G
Sbjct: 888  ASGFPGTKGEMGMMGPP---GPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKG 944

Query: 407  LPGLPGPPG-----LPGMKGDRGVVGEP------GPKGEQGASGEEGEAGERGELGDIGL 455
             PGLPGPPG     L G KG++G  G P      GPKG QG  G+ G+ G  G+ G  G 
Sbjct: 945  EPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGP 1004

Query: 456  PGPKGSAGNPGEPGLRGPEGSR------GLPGVEGPRGPPGPRGVQGEQGATGLPGVQGP 509
            PGPKG+ G PG+PGL GP G +      G PG +G  GPPGP GV G+ G+ GLPG +G 
Sbjct: 1005 PGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGD 1064

Query: 510  PGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQ 569
             G                             P   + GLPG PGP G PG PG  G PG 
Sbjct: 1065 KG----------------------------DPGISSIGLPGLPGPKGEPGLPGYPGNPGI 1096

Query: 570  MGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGPAS---- 624
             G  G PG+ G PG  G +G  G  G  G  GPPG +G +G PG  GLPG+PGP      
Sbjct: 1097 KGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGH 1156

Query: 625  YGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEP 660
             G+ G  GE+G PG  GIPG  G  G PG PGF  P
Sbjct: 1157 PGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNP 1192



 Score =  510 bits (1314), Expect = e-144
 Identities = 314/730 (43%), Positives = 367/730 (50%), Gaps = 125/730 (17%)

Query: 24   QRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGP----------PGPAGEPGKPGAP 73
            Q+G  G+ G  GP G PG+PG  G  G  G KG PG            G  G PG PG P
Sbjct: 513  QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572

Query: 74   GKPGTPGADGLTG---PDGSPGSIGSKGQKGEPGVPGSRGFPGRGIP------GPPGP-- 122
            G PGTPG DGL G   P G PG I  KG++G PG PG  G PG   P      GPPGP  
Sbjct: 573  GLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVG 632

Query: 123  ----PGTAGLPGELGRVGPVGDPGRR----GPPGPPGPPGPRGTIGFHDGDPLCPNAC-- 172
                 G AG PG+ G  GP GDPG+     G PG PG PG  G +G   GDP  P     
Sbjct: 633  EKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGL-PGDPGLPGQPGL 691

Query: 173  -------------------PPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGEL 213
                               PPG  G+PG+PG  G  G  G IG  G  G  G  G +GE 
Sbjct: 692  PGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEP 751

Query: 214  GEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPK 273
            G     GPPG  GL G  G +G KG++G  G  G PG  GL G PG +G  GP G+ GP 
Sbjct: 752  G-FALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPM 810

Query: 274  GDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPG-----PPGDAGLQG 328
            G  G  G     G+ GP G  G+PG  G+ G+ G+PG KG+PG PG     PPG+ G  G
Sbjct: 811  GPPGLPGI----GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPG 866

Query: 329  LPGVPGI---PGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRG 385
            +PG PG    PG+ G+ G+ G++G PG  G+MG  G PG   PPG +G  G  G+PG +G
Sbjct: 867  IPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPG---PPGPLGIPGRSGVPGLKG 923

Query: 386  ELGPVGSPGLPGKLGSLGSPGLPGLPGPPG-----LPGMKGDRGVVGEPG------PKGE 434
            + G  G PGLPG  G  GS G PGLPGPPG     L G KG++G  G PG      PKG 
Sbjct: 924  DDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGY 983

Query: 435  QGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRG------LPGVEGPRGP 488
            QG  G+ G+ G  G+ G  G PGPKG+ G PG+PGL GP G +G       PG +G  GP
Sbjct: 984  QGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGP 1043

Query: 489  PGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGL 548
            PGP GV G+ G+ GLPG +G  G                             P   + GL
Sbjct: 1044 PGPSGVPGQPGSPGLPGQKGDKGD----------------------------PGISSIGL 1075

Query: 549  PGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGP 607
            PG PGP G PG PG  G PG  G  G PG+ G PG  G +G  G  G  G  GPPG +G 
Sbjct: 1076 PGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGI 1135

Query: 608  NGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQA 667
            +G PG  GLPG+PGP   G           G  G PG PG  G PG  G   PA    + 
Sbjct: 1136 SGPPGNPGLPGEPGPVGGG-----------GHPGQPGPPGEKGKPGQDGIPGPAGQKGEP 1184

Query: 668  GQRAF-NKGP 676
            GQ  F N GP
Sbjct: 1185 GQPGFGNPGP 1194



 Score =  506 bits (1302), Expect = e-143
 Identities = 328/811 (40%), Positives = 378/811 (46%), Gaps = 190/811 (23%)

Query: 24  QRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADG 83
           +RG PG  G PG  GPPG PGI G+ G+ G       PGP G PG PG PG  G PG  G
Sbjct: 130 ERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTG 189

Query: 84  LTGPDGSPGSIGSKGQKGEPGVPGSRGFPG------------RGIPGPPGPP-------- 123
           + GP G PG  G  G  G PG+PG +G  G            +G+ GPPGPP        
Sbjct: 190 IPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKR 249

Query: 124 --------GTAGLPGELGRVGPVGDPGRRGPPGPP----------GPPGPRGTIG--FHD 163
                   G  GLPG+    GP G PG RGPPGPP          G PG RG  G    +
Sbjct: 250 PIDVEFQKGDQGLPGDR---GPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGEN 306

Query: 164 GDPLCPNACPPGRSGYPGLPGMRGHKGAKGE-------------------------IGEP 198
           G P  P    PG  GYPG PG  G KG KG+                         IG P
Sbjct: 307 GQPGIPGL--PGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLP 364

Query: 199 GRQGHKGEEGDQGELGEVGAQGPPGA--QGLRGITGIVGDKGEKGAR-----------GL 245
           G  G KGE G  G  G  G  GPPGA   G  G  G  G++G+KG             GL
Sbjct: 365 GLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGL 424

Query: 246 DGEPGPQGLPGAPGDQG----------QRGPPGEAGPKGDRGAEGARGI----------- 284
           DG+PG  GLPG PG  G          + GPPG  G  GD+G +G +G+           
Sbjct: 425 DGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNC 484

Query: 285 --PGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPG----- 337
              G+ GP G  GLPG+ G  G  G PG KGE G+ G  G  GL G+PG PG PG     
Sbjct: 485 IGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSK 544

Query: 338 --------AKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGP 389
                     G+ G+KG  G+PG PG  G  G PGQ G PG  GP+G  G    +GE GP
Sbjct: 545 GEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGP 604

Query: 390 VGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGE------PGPKGEQGAS----G 439
            G+PGLPG  G++G  G PG  GPPG  G KG +GV G       PGPKG+ G +    G
Sbjct: 605 PGNPGLPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPG 663

Query: 440 EEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQG 499
           + G  G  G  GD+GLPG  G  G PG PG+ G +G  G+PG+ G  GPPGP+       
Sbjct: 664 KPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI-GLPGPPGPK------- 715

Query: 500 ATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPG--------R 551
             G PG+ GPPG   T   I                  L+ P  G  G PG         
Sbjct: 716 --GFPGIPGPPGAPGTPGRI-----------------GLEGP-PGPPGFPGPKGEPGFAL 755

Query: 552 PGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGAL---GLRGPKGDLGEKGERGPPG---- 604
           PGPPGPPG PG  G  G  G RG PG  GPPG     GL GPKGD+G  G+ GP G    
Sbjct: 756 PGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGL 815

Query: 605 --------RGPNGLPGAIGLP---------GDPGPASYGRNGRDGERGPPGVAGIPGVPG 647
                    GP G+PG IG P         GDPGP      G  GERG PG+ G PG  G
Sbjct: 816 PGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIG 875

Query: 648 PPGPPGLPGFCEPASCTMQAGQRAFNKGPDP 678
           PPG PGLPG    +      G+      P P
Sbjct: 876 PPGSPGLPGKAGASGFPGTKGEMGMMGPPGP 906



 Score =  496 bits (1276), Expect = e-140
 Identities = 329/786 (41%), Positives = 376/786 (47%), Gaps = 162/786 (20%)

Query: 26  GPPGEQGPPGPPGPPGVPGIDGID--------GDRGPKGPPGPPGPAGEPGKP------- 70
           GPPG  GPPGPPG PG  G  G++        G++G +GPPGPPG   E  +P       
Sbjct: 198 GPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQK 257

Query: 71  ---GAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR----GIPGPPGPP 123
              G PG  G PG  G+ GP G PG  G KG+KGE G PG RG PG+    G PG PG P
Sbjct: 258 GDQGLPGDRGPPGPPGIRGPPGPPG--GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLP 315

Query: 124 GTAGLPGELGRVGPVGDPGRRGPPGPPGP----------------------PGPRGTIGF 161
           G  G PGE GR G  G  G  GPPGPPG                       PG +G  GF
Sbjct: 316 GDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGF 375

Query: 162 HD-----GDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIG-----------EPGRQGHKG 205
                  G P  P A   G  G PG PG RG KG +G  G           +PG  G  G
Sbjct: 376 PGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPG 435

Query: 206 EEGDQG-------ELGEVGAQGPPGAQGLRGITGIVGDKGEKG-------ARGLDGEPGP 251
             G  G       E+ E G  GPPG+ G +G+ G  G KG+KG         G+ G PG 
Sbjct: 436 PPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495

Query: 252 QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDG----IPG 307
            GLPG PG  G  G PG+ G KG  GA G +G+PG+PG  G  G PG  G  G     PG
Sbjct: 496 PGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG 555

Query: 308 MPGTKGEPGKPGPPGDAGLQGLPG---VPGIPGAKG------VAGEKGSTGAPGKPGQMG 358
           M G KGE G PG PG  GL G PG   +PG+PG KG        GE+G  G PG PG  G
Sbjct: 556 MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPG 615

Query: 359 NSGKPGQQG--PPGEVGPRGPQG---------LPGSRGELGPV----GSPGLPGK----- 398
           N G  G  G  PPG VG +G QG         +PG +G+ G      G PGLPG      
Sbjct: 616 NIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDG 675

Query: 399 -LGSLGSPGLPGLPGPPGLPGMKGDRGV--VGEPGPKGEQGASGEEGEAGERGELGDIGL 455
            +G  G PGLPG PG PG+PG KG+ G+  +G PGP G +G  G  G  G  G  G IGL
Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGL 735

Query: 456 PGPKGSAGNPGEPGLRGPEGSRG--LPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRA 513
            GP      PG PG  GP+G  G  LPG  GP G PG +G  G +G  G PG  GPPGR 
Sbjct: 736 EGP------PGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRT 789

Query: 514 PTDQHIKQVCMRVIQEHFAEMAASLKRP--DSGATGLPGRPGPPG--------PPGPPGE 563
             D                     L  P  D G  G PG  GPPG        PPGPPG 
Sbjct: 790 GLD--------------------GLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI 829

Query: 564 NGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR-GPNGLPGAIGLPGDPG- 621
            G  GQ G+ G+PG KG PG  GL  P G  GE+G  G PG  GP G PG+ GLPG  G 
Sbjct: 830 PGPIGQPGLHGIPGEKGDPGPPGLDVP-GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGA 888

Query: 622 ---PASYGRNGRDGERGPPGV------AGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAF 672
              P + G  G  G  GPPG       +G+PG+ G  G  G PG   P       G+   
Sbjct: 889 SGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGL 948

Query: 673 NKGPDP 678
              P P
Sbjct: 949 PGPPGP 954



 Score =  476 bits (1226), Expect = e-134
 Identities = 288/641 (44%), Positives = 330/641 (51%), Gaps = 102/641 (15%)

Query: 26   GPPGEQGPPG---PPGP------PGVP------GIDGIDGDRGPKGPPGPPGPAGEPGKP 70
            GPPGE+G PG    PGP      PG+P      G  G  G+ G  GPPGPPGP G PG+ 
Sbjct: 857  GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRS 916

Query: 71   GAP---------GKPGTPGADGLTGPDGSPG-----------SIGSKGQKGEPGVPGSRG 110
            G P         G+PG PG  G  G  G PG            +GSKG+KGEPG+PG  G
Sbjct: 917  GVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPG 976

Query: 111  FPG----RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDP 166
              G    +G+PG PG PG +G PG  G  GP G+PG  G PG  GPPG +GTIG      
Sbjct: 977  VSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPG 1036

Query: 167  LCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQ--GHKGEEGDQGELGEVGAQGPPGA 224
                  PPG SG PG PG  G  G KG+ G+PG    G  G  G +GE G  G  G PG 
Sbjct: 1037 PQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGI 1096

Query: 225  QGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGI 284
            +G  G  G+ G  G  GA+G  G PG  G PG PG +G  GPPG  G  G+ G  G  G 
Sbjct: 1097 KGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGH 1156

Query: 285  PGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGK-----PGPP---------GDAGLQGLP 330
            PG PGP G+ G P   G+DGIPG  G KGEPG+     PGPP         GD GL G+P
Sbjct: 1157 PGQPGPPGEKGKP---GQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIP 1213

Query: 331  GVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPV 390
            G PG+PG KG  G  G  G  G PG  G+ G P  +GP G  GP+GP G PG +G  GP 
Sbjct: 1214 GNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG-PALEGPKGNPGPQGPPGRPGFQGLPGPE 1272

Query: 391  GSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGEL 450
            G PGLPG  G  G  G PG PG PGLPG+KGD+G  G  G  G  G +G +G+ G  G  
Sbjct: 1273 GPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVP 1332

Query: 451  GDIGLPGPK---GSAGNPGEPGLRGPEGSRGLPGVEGP----RGPPGPRGVQGEQGATGL 503
            G  G+ GP    GSAG  GEPGL GP G  GLPG  G     +G  GP G+ G+ G  GL
Sbjct: 1333 GFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGL 1392

Query: 504  PGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGE 563
            PG QGP                                     GLPG  GPPG PG  G 
Sbjct: 1393 PGPQGP------------------------------------QGLPGPTGPPGDPGRNGL 1416

Query: 564  NGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG 604
             GF G  G +G PG+ G PG  GL GP G  G +G  GPPG
Sbjct: 1417 PGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1457



 Score =  456 bits (1174), Expect = e-128
 Identities = 275/634 (43%), Positives = 322/634 (50%), Gaps = 118/634 (18%)

Query: 24   QRGPPGEQGPPGPPGPPGVPGIDG---------IDGDRGPKGPPGPPGPAGEPGKPGAPG 74
            +RG PG  G PGP GPPG PG+ G           G+ G  GPPGPPGP G PG+ G PG
Sbjct: 861  ERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPG 920

Query: 75   ---------KPGTPGADGLTGPDGSPGS-----------IGSKGQKGEPGVPGSRGFPG- 113
                     +PG PG  G  G  G PG            +GSKG+KGEPG+PG  G  G 
Sbjct: 921  LKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGP 980

Query: 114  ---RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFH-------- 162
               +G+PG PG PG +G PG  G  GP G+PG  G PG  GPPG +GTIG          
Sbjct: 981  KGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGV 1040

Query: 163  DGDPLCPNACPPGRSGYPGLPGMRGHKG--------------AKGEIGEPGRQGHKGEEG 208
            +G P  P+  P G+ G PGLPG +G KG               KGE G PG  G+ G +G
Sbjct: 1041 EGPP-GPSGVP-GQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKG 1098

Query: 209  DQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPG 268
              G+ G  G  G PGA+G  G+ G  G  G  G +G+ G PG  GLPG PG  G  G PG
Sbjct: 1099 SVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPG 1158

Query: 269  EAGPKGDRGAEGARGIPGLPGPKGDTGLPGVD--GRDGIPGMPGTKGEPGKPGPPGDAGL 326
            + GP G++G  G  GIPG  G KG+ G PG    G  G+PG+ G KG+ G PG PG+ GL
Sbjct: 1159 QPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGL 1218

Query: 327  QGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVG------PRGPQGL 380
             G  G PG  G  GV G  G  G+PG P   G  G PG QGPPG  G      P GP GL
Sbjct: 1219 PGPKGEPGFHGFPGVQGPPGPPGSPG-PALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGL 1277

Query: 381  PGS------RGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPG---- 430
            PG+      +G  G  G PGLPG  G  G PGL G PG PGL GMKGD G+ G PG    
Sbjct: 1278 PGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGM 1337

Query: 431  --PKGEQGASGEEGEAGERGELGDIGLPGPKGSA----GNPGEPGLRGPEGSRGLPGVEG 484
              P G  G++G EGE G  G  G  GLPGP G +    G+ G PG+ G  G +GLPG +G
Sbjct: 1338 KGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQG 1397

Query: 485  PRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSG 544
            P+G PGP G  G+ G  GLPG  G  GR                               G
Sbjct: 1398 PQGLPGPTGPPGDPGRNGLPGFDGAGGR------------------------------KG 1427

Query: 545  ATGLPGRP------GPPGPPGPPGENGFPGQMGI 572
              GLPG+P      GPPGP G  G  G PG   +
Sbjct: 1428 DPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSV 1461



 Score =  426 bits (1096), Expect = e-119
 Identities = 278/656 (42%), Positives = 312/656 (47%), Gaps = 145/656 (22%)

Query: 90  SPGS----IGSKGQKGEPGVPGSRGFPGR-GIPGPPGPPGTAGLPGELGRVGPVGDPGRR 144
           SPGS     G KG+KGE G PG  G PG  G PGP GPPG  G  G+ G  GP G  G R
Sbjct: 33  SPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIR 92

Query: 145 GPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHK 204
           GPPG PG PG                         PGLPGM GH GA G  G PG  G K
Sbjct: 93  GPPGLPGFPGT------------------------PGLPGMPGHDGAPGPQGIPGCNGTK 128

Query: 205 GEEGDQGELGEVGAQGPPGAQGLRGITGIVGD------KGEKGARGLDGEPGPQGLPGAP 258
           GE G  G  G  G QGPPG  G+ G+ G  G        G KG  G  G PG QGLPG  
Sbjct: 129 GERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPT 188

Query: 259 GDQGQRGPPGE-----------------------AGPKGDRGAEGARGIPGLPG------ 289
           G  G  GPPG                         GPKG++G +G +G PG PG      
Sbjct: 189 GIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQK 248

Query: 290 -------PKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVA 342
                   KGD GLPG  G  G PG+ G  G PG  G  G+ G QG PG  G PG  G  
Sbjct: 249 RPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG--GEKGEKGEQGEPGKRGKPGKDGEN 306

Query: 343 GEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGL----PGSRGELGPVGSPGLPGK 398
           G+ G  G PG PG  G  G+ G++G  G+ GP GP GL    PG+   +G  G+ GLPG 
Sbjct: 307 GQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGL 366

Query: 399 LGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGP 458
            G  G  G PG+ GPPGLPG  G   V+G PGP G  G  G++G+ G  G    I +PGP
Sbjct: 367 PGEKGERGFPGIQGPPGLPGPPG-AAVMGPPGPPGFPGERGQKGDEGPPG----ISIPGP 421

Query: 459 KGSAGNPGEPGLRGPEGSRG----------LPGVEGPRGPPGPRGVQGEQGATGLPGVQG 508
            G  G PG PGL GP G  G           PG  GP G PG +G+QGEQG  G  G   
Sbjct: 422 PGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKG--- 478

Query: 509 PPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPG 568
                         C   I               +G +G PG+PG PG PGPPG  GFPG
Sbjct: 479 ------------DTCFNCI--------------GTGISGPPGQPGLPGLPGPPGSLGFPG 512

Query: 569 Q---------MGIRGLPGIKGPPGALGLRGPKGD----------LGEKGERGPPGR---- 605
           Q          G +GLPGI G PGA G  G KG+           G+KGE G PG     
Sbjct: 513 QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572

Query: 606 GPNGLPGAIGLPGDPGP-ASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEP 660
           G  G PG  GLPG PGP    G     GERGPPG  G+PG+PG  GP G PGF  P
Sbjct: 573 GLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPP 628



 Score =  283 bits (724), Expect = 4e-76
 Identities = 165/355 (46%), Positives = 188/355 (52%), Gaps = 37/355 (10%)

Query: 15   LLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPG 74
            L GL      +G PG  G PG PGPPG  GI G  G+ G  G PGP G  G PG+PG PG
Sbjct: 1105 LPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164

Query: 75   KPGTPGADGLTGPDGS--------------PGSIGSKGQKGEPGVPGSRGFPGRGIPGPP 120
            + G PG DG+ GP G               PG  G  GQKG+ G+PG  G PG  +PGP 
Sbjct: 1165 EKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPG--LPGPK 1222

Query: 121  GPPGTAGLPGELGRVGPVGDPGR--RGPPGPPGPPGPRGTIGFH-----DGDPLCP-NAC 172
            G PG  G PG  G  GP G PG    GP G PGP GP G  GF      +G P  P N  
Sbjct: 1223 GEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGG 1282

Query: 173  PPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITG 232
              G  G PG PG+ G  G KG+ G PG QG+ G  G  G  G+ G  G PG  G++G +G
Sbjct: 1283 IKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSG 1342

Query: 233  IVGDKGEKGARGLDGEPGPQGLPGAPG-------DQGQRGPPGEAGPKGDRGAEGARGIP 285
            + G  G +G  GL G PGP GLPG  G       D G  G PG+ G KG  G +G +G+P
Sbjct: 1343 VPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLP 1402

Query: 286  GLPGPKGD---TGLPGVD---GRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPG 334
            G  GP GD    GLPG D   GR G PG+PG  G  G  GPPG  GLQG PG PG
Sbjct: 1403 GPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1457


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score =  557 bits (1436), Expect = e-158
 Identities = 333/722 (46%), Positives = 381/722 (52%), Gaps = 115/722 (15%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPG-----PPGPAGEPGKPGAPGKPGTPG 80
            G  G+ G PG PG PG PG+ GI G +G  G PG     PPGP G PG PG PG PGTPG
Sbjct: 672  GRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPG 731

Query: 81   ADGLTGPDGSPGSIGSKGQKGE--PGVPGSRGFPG----------RGIPGPPGPPGTAGL 128
              GL GP G PG  G KG+ G   PG PG  G PG          RG PGPPGPPG  GL
Sbjct: 732  RIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGL 791

Query: 129  ---PGELGRVGPVGDPGR-----------RGPPGPPGPPGPRGTIGFHD-----GDPLCP 169
               PG  G VGP G PG            +GPPGPPG PGP G  G H      GDP  P
Sbjct: 792  DGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPP 851

Query: 170  NAC---PPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQG 226
                  PPG  G PG+PG  G  G  G  G PG+ G  G  G +GE+G +G  GPPG  G
Sbjct: 852  GLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLG 911

Query: 227  LRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGP-----KGDRGAEGA 281
            + G +G+ G KG+ G +G  G PGP G  G+ G+ G  GPPG   P     KG++G  G 
Sbjct: 912  IPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGL 971

Query: 282  RGIPGLPGPKG------DTGLPGVDGRDGIPGMPGTKGEPGKPGPPG------------D 323
             GIPG+ GPKG      D G PG+ G+ G+PG PG KG PG PG PG            D
Sbjct: 972  PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGD 1031

Query: 324  AGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSG-----KPGQQGPPGEVGPRGPQ 378
             G  G  GV G PG  GV G+ GS G PG+ G  G+ G      PG  GP GE G  G  
Sbjct: 1032 MGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYP 1091

Query: 379  GLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKG------DRGVVGEPGPK 432
            G PG +G +G  G PGLPG  G+ G PGLPG PG PG PG KG      + G+ GEPGP 
Sbjct: 1092 GNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPV 1151

Query: 433  GEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPG-----------LRGPEGSRGLPG 481
            G  G  G+ G  GE+G+ G  G+PGP G  G PG+PG           L G +G  GLPG
Sbjct: 1152 GGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPG 1211

Query: 482  VEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRP 541
            + G  G PGP+G   E G  G PGVQGPPG   +                     +L+ P
Sbjct: 1212 IPGNPGLPGPKG---EPGFHGFPGVQGPPGPPGSP------------------GPALEGP 1250

Query: 542  --DSGATGLPGRPGPPG---PPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGE 596
              + G  G PGRPGP G    PGP G  G PG  GI+G  G  G PG  GL G KGD G 
Sbjct: 1251 KGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGP 1310

Query: 597  KGERGPPGR-GPNGLPGAIGLPGDPG-PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGL 654
             G +G PGR G NG+ G  GLPG PG P   G +G  G  GP G    PG+ GPPGPPGL
Sbjct: 1311 PGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGE---PGLIGPPGPPGL 1367

Query: 655  PG 656
            PG
Sbjct: 1368 PG 1369



 Score =  551 bits (1420), Expect = e-157
 Identities = 327/701 (46%), Positives = 372/701 (53%), Gaps = 88/701 (12%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 85
            GP G++G PGPPGPPG  G+DG+ G +G  GP G PGP G PG PG  G  G PG  G+ 
Sbjct: 772  GPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGI-GVQGPPGPPGIP 830

Query: 86   GPDGSPGSIGSKGQKGEPGVPG--------SRGFPG-RGIPGPPGPPGTAGLPGELGRVG 136
            GP G PG  G  G+KG+PG PG         RG PG  G PGP GPPG+ GLPG+ G  G
Sbjct: 831  GPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASG 890

Query: 137  PVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIG 196
              G  G  G  GPPGPPGP G  G   G P        G  G PGLPG  G KG+KGE G
Sbjct: 891  FPGTKGEMGMMGPPGPPGPLGIPG-RSGVPGLKG--DDGLQGQPGLPGPTGEKGSKGEPG 947

Query: 197  EPGRQGHKGEE--GDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARG---LDGEPGP 251
             PG  G       G +GE GE G  G PG  G +G  G+ GD G+ G  G   L G PGP
Sbjct: 948  LPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGP 1007

Query: 252  QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGI---------------PGLPGPKGDTGL 296
            +G PG PG  G  GPPG  G  GD G  G +G+               PGLPG KGD G 
Sbjct: 1008 KGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGD 1067

Query: 297  PGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQG------LPGVPGIPGAKGVAGEKGSTGA 350
            PG+    G+PG+PG KGEPG PG PG+ G++G      LPG+PG PGAKG  G  G  G 
Sbjct: 1068 PGISSI-GLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGT 1126

Query: 351  PGKPGQMGNSGKPGQQGPPGEVGP---RGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGL 407
            PG PG  G SG PG  G PGE GP    G  G PG  GE G  G  G+PG  G  G PG 
Sbjct: 1127 PGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQ 1186

Query: 408  PGL--PGPPGLPGMKGDRGV---------VGEPGPKGEQGASGEEGEAGERGELGDIG-- 454
            PG   PGPPGLPG+ G +G           G PGPKGE G  G  G  G  G  G  G  
Sbjct: 1187 PGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPA 1246

Query: 455  LPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAP 514
            L GPKG+ G  G PG  GP G +GLPG EGP G PG  G++GE+G  G PG+ G PG   
Sbjct: 1247 LEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKG 1306

Query: 515  TDQHIKQVCMRVIQEHFAEMAASLKRPD-SGATGLPGRPGPPGPPGPPGENGFPGQMGIR 573
                          +    +  +  RP  +G  G PG PG PG PG  G +G PG  G  
Sbjct: 1307 -------------DQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPE 1353

Query: 574  GLPGIKGPPGALGLRGPKGD-LGEKGERGPPG-------------RGPNGLPGAIGLPGD 619
            G PG+ GPPG  GL GP G  +  KG+ GPPG             +GP GLPG  G PGD
Sbjct: 1354 GEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGD 1413

Query: 620  PG----PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
            PG    P   G  GR G+ G PG  G  G+ GPPGP GL G
Sbjct: 1414 PGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQG 1454



 Score =  538 bits (1387), Expect = e-153
 Identities = 335/768 (43%), Positives = 382/768 (49%), Gaps = 162/768 (21%)

Query: 7    DRGALGLL----LLGLCLCAAQRGPPGEQGPPGPPG---------PPGVPGIDGIDGDRG 53
            D+G LG      L GL     Q G PG  GP G PG         PPG PG+ G+ G+ G
Sbjct: 559  DKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIG 618

Query: 54   PKGPPG--PPGPAGE---------PGKPGAPG-------------KPGTPGADGLTGPDG 89
            P GPPG  PPGP GE         PG+PG PG             KPG PG  G  G  G
Sbjct: 619  PMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVG 678

Query: 90   SPGSIGSKGQKGEPGVPGSRG---FPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGP 146
             PG  G  GQ G PG+PGS+G    PG G+PGPPGP G  G+PG  G  G  G  G  GP
Sbjct: 679  LPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGP 738

Query: 147  PGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGE 206
            PGPPG PGP+G  GF       P   PPG  G PG  G  G KG +G  G PG  G  G 
Sbjct: 739  PGPPGFPGPKGEPGF-----ALPG--PPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGL 791

Query: 207  EGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGP 266
            +G  G  G+VG  G PG  G  G+ GI G +G  G  G+ G  G  GL G PG++G  GP
Sbjct: 792  DGLPGPKGDVGPNGQPGPMGPPGLPGI-GVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGP 850

Query: 267  PG--EAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDA 324
            PG    GP G+RG+    GIPG PGP G  G PG+ G+ G  G PGTKGE G  GPPG  
Sbjct: 851  PGLDVPGPPGERGSP---GIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPP 907

Query: 325  GLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEV------------ 372
            G  G+PG  G+PG KG  G +G  G PG  G+ G+ G+PG  GPPG +            
Sbjct: 908  GPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKG 967

Query: 373  -----------GPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLP---GPPGLPG 418
                       GP+G QGLPG  G+ G  G PGLPG  G  G+PGLPG P   GPPGL G
Sbjct: 968  EPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKG 1027

Query: 419  MKGD------RGVVGEPGPKGEQGASGEEGEAGERGELGD--------IGLPGP------ 458
              GD      +GV G PGP G  G  G  G  G++G+ GD         GLPGP      
Sbjct: 1028 TIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGL 1087

Query: 459  ---------KGSAGNPGEPGLRGPEGSR---GLPGVEGPRGPPGPRGVQGEQGATGLPGV 506
                     KGS G+PG PGL G  G++   GLPG  G  GPPGP+G+ G  G  GLPG 
Sbjct: 1088 PGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGE 1147

Query: 507  QGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGF 566
             GP                                  G  G PG+PGPPG  G PG++G 
Sbjct: 1148 PGP---------------------------------VGGGGHPGQPGPPGEKGKPGQDGI 1174

Query: 567  PGQMGIRGLP-----GIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGL---- 616
            PG  G +G P     G  GPPG  GL G KGD G  G  G PG  GP G PG  G     
Sbjct: 1175 PGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQ 1234

Query: 617  -----PGDPGPASYGRNGRDGERGP---PGVAGIPGVPGPPGPPGLPG 656
                 PG PGPA  G  G  G +GP   PG  G  G+PGP GPPGLPG
Sbjct: 1235 GPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPG 1282



 Score =  521 bits (1343), Expect = e-148
 Identities = 337/759 (44%), Positives = 383/759 (50%), Gaps = 136/759 (17%)

Query: 26  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 85
           G PG  G PGP GPPG  G  G DG  GP GP G  GP G PG PG PG PG PG DG  
Sbjct: 57  GHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAP 116

Query: 86  GPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRV------GPVG 139
           GP G PG  G+KG++G PG P   GFP  G+ GPPGPPG  G+ GE G +      GP G
Sbjct: 117 GPQGIPGCNGTKGERGFPGSP---GFP--GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKG 171

Query: 140 DPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHK--------GA 191
           +PG  GPPG  G PGP G  G     P+ P   PPG  G PG PG+ G K        G 
Sbjct: 172 NPGYPGPPGIQGLPGPTGIPG-----PIGPPG-PPGLMGPPGPPGLPGPKGNMGLNFQGP 225

Query: 192 KGEIGEPGRQGHKG----------------EEGDQGELGEVGAQGPPGAQGLRGITGIVG 235
           KGE GE G QG  G                ++GDQG  G+ G  GPPG +G  G  G  G
Sbjct: 226 KGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG--G 283

Query: 236 DKGEKGAR---------GLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPG 286
           +KGEKG +         G DGE G  G+PG PGD G  G PG  G KG +G  G  G PG
Sbjct: 284 EKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPG 343

Query: 287 LP----------GPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIP 336
           L           G KG+ GLPG+ G  G  G PG +G PG PGPPG A + G PG PG P
Sbjct: 344 LVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPG-AAVMGPPGPPGFP 402

Query: 337 GAKGVAGEKGSTG--APGKPGQMGNSGKPGQQGPPGEVGPR----------GPQGLPGSR 384
           G +G  G++G  G   PG PG  G  G PG  GPPG  GP           GP G PGS 
Sbjct: 403 GERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSP 462

Query: 385 GELGPVGSPGLPGKLGSL-------------GSPGLPGLPGPP---GLPGMKGDRGVVGE 428
           G+ G  G  G+ G  G               G PGLPGLPGPP   G PG KG++G  G 
Sbjct: 463 GDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGA 522

Query: 429 PGPK---GEQGASGEEGEAGERGELGDI----GLPGPKGSAGNPGE---PGLRGPEGSRG 478
            GPK   G  GA G  G  G +GE GDI    G+ G KG  G+PG    PGL G  G  G
Sbjct: 523 TGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDG 582

Query: 479 LPGVEGPRGPP------GPRGVQGEQGATGLP---GVQGPPGRAPT----DQHIKQVCMR 525
           LPG+ GP+G P      G RG  G  G  GLP   G  GPPG  P     ++ I+ V   
Sbjct: 583 LPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGN 642

Query: 526 VIQEHF----AEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGP 581
             Q        +   ++ +P  G  GLPG PG  G  G PG+ G PGQ G+ G+PG KG 
Sbjct: 643 PGQPGIPGPKGDPGQTITQP--GKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGE 700

Query: 582 PG--ALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGV 639
           PG   +GL GP G  G  G  GPP  G  G PG IGL G PGP      G  G +G PG 
Sbjct: 701 PGIPGIGLPGPPGPKGFPGIPGPP--GAPGTPGRIGLEGPPGPP-----GFPGPKGEPGF 753

Query: 640 AGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPDP 678
           A    +PGPPGPPGLPGF          G R F   P P
Sbjct: 754 A----LPGPPGPPGLPGF---KGALGPKGDRGFPGPPGP 785



 Score =  518 bits (1333), Expect = e-147
 Identities = 336/804 (41%), Positives = 383/804 (47%), Gaps = 157/804 (19%)

Query: 4    TARDRGALGLLLLGLCLCAAQRGPPGEQGPPGPPGPPGV-----PGIDGIDGDRGPKGPP 58
            T  ++G +GL   GL     +RG PG QGPPG PGPPG      PG  G  G+RG KG  
Sbjct: 354  TIGEKGNIGLP--GLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDE 411

Query: 59   GPPG-----PAGEPGKPGAPGKPGTPGADGL----------TGPDGSPGSIGSKGQKGEP 103
            GPPG     P G  G+PGAPG PG PG  G            GP G PGS G KG +GE 
Sbjct: 412  GPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQ 471

Query: 104  GVPGSRGF-------------PGR-GIPGPPGPPGTAGLPGELGR------VGPVGDPGR 143
            GV G +G              PG+ G+PG PGPPG+ G PG+ G        GP G PG 
Sbjct: 472  GVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGI 531

Query: 144  RGPPGPPGPPGPRGTIGF------------HDGDPLCPNAC----PPGRSGYPGLPGMRG 187
             G PG PG PG +G  G               G P  P        PG+ G PGLPG +G
Sbjct: 532  PGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKG 591

Query: 188  HKGA---KGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARG 244
              G    KGE G PG  G  G  G+ G +G  G  GPPG  G +GI G+ G+ G+ G  G
Sbjct: 592  EPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQPGIPG 650

Query: 245  LDGEPGPQ-------------------GLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIP 285
              G+PG                     GLPG PG  GQ G PG  G KG+ G  G  G+P
Sbjct: 651  PKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI-GLP 709

Query: 286  GLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAG-----LQGLPGVPGIPGAKG 340
            G PGPKG  G+PG  G  G PG  G +G PG PG PG  G     L G PG PG+PG KG
Sbjct: 710  GPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKG 769

Query: 341  VAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGP--------------QGLPGSRGE 386
              G KG  G PG PG  G +G  G  GP G+VGP G               QG PG  G 
Sbjct: 770  ALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI 829

Query: 387  LGPVGSPGL-----------------PGKLGSLGSPGLPGLPGP---PGLPGMKGDRGVV 426
             GP+G PGL                 PG  G  GSPG+PG PGP   PG PG+ G  G  
Sbjct: 830  PGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS 889

Query: 427  GEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPR 486
            G PG KGE G  G  G  G  G  G  G+PG KG  G  G+PGL GP G +G  G  G  
Sbjct: 890  GFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLP 949

Query: 487  GPPGP--------RGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASL 538
            GPPGP        +G +GE G  G+PGV GP G                           
Sbjct: 950  GPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPG--------------------- 988

Query: 539  KRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKG 598
               D G  GL G+PG PGPPGP G  G PGQ G+ G PG+KG  G +G  GP+G  G  G
Sbjct: 989  ---DPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPG 1045

Query: 599  ERGPPGR-GPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPG---PPGPPGL 654
              G PG+ G  GLPG  G  GDPG +S G  G  G +G PG+ G PG PG     G PGL
Sbjct: 1046 PSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGL 1105

Query: 655  PGFCEPASCTMQAGQRAFNKGPDP 678
            PG         Q G   F   P P
Sbjct: 1106 PGLPGTPGAKGQPGLPGFPGTPGP 1129



 Score =  515 bits (1326), Expect = e-146
 Identities = 332/816 (40%), Positives = 388/816 (47%), Gaps = 195/816 (23%)

Query: 7    DRGALGLLLLGLCLCAAQRGPPGEQGP----------------PGPPGPPGVPGIDGIDG 50
            D G  G+ + G      Q G PG  GP                PGPPGPPG PG  G+ G
Sbjct: 410  DEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQG 469

Query: 51   DRGPK----------------GPPGPPGPAGEPGKPGA---------------------P 73
            ++G K                GPPG PG  G PG PG+                     P
Sbjct: 470  EQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLP 529

Query: 74   GKPGTPGADGLTGPDGSPGSI-------GSKGQKGEPGVPGSRGFPGR-------GIPGP 119
            G PG PGA G  G  G PG I       G KG+ G PG PG  G PG        G+PGP
Sbjct: 530  GIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGP 589

Query: 120  P------------GPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPL 167
                         GPPG  GLPG  G +GP+G PG  GPPGP G  G +G  G + G P 
Sbjct: 590  KGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPG-FGPPGPVGEKGIQGVAG-NPGQPG 647

Query: 168  CP--------NACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELG--EVG 217
             P            PG+ G PG PG  G  G  G+ G PG+ G  G  G +GE G   +G
Sbjct: 648  IPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIG 707

Query: 218  AQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQG-----------LPGAPGDQGQRGP 266
              GPPG +G  GI G  G  G  G  GL+G PGP G           LPG PG  G  G 
Sbjct: 708  LPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGF 767

Query: 267  PGEAGPKGDRGAEGARGIP------GLPGPKGDT-------------------------- 294
             G  GPKGDRG  G  G P      GLPGPKGD                           
Sbjct: 768  KGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPP 827

Query: 295  GLPGVDGRDGIPGMPGTKGEPGK-----PGPPGDAGLQGLPGVP---GIPGAKGVAGEKG 346
            G+PG  G+ G+ G+PG KG+PG      PGPPG+ G  G+PG P   G PG+ G+ G+ G
Sbjct: 828  GIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAG 887

Query: 347  STGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPG 406
            ++G PG  G+MG  G P   GPPG +G  G  G+PG +G+ G  G PGLPG  G  GS G
Sbjct: 888  ASGFPGTKGEMGMMGPP---GPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKG 944

Query: 407  LPGLPGPPG-----LPGMKGDRGVVGEP------GPKGEQGASGEEGEAGERGELGDIGL 455
             PGLPGPPG     L G KG++G  G P      GPKG QG  G+ G+ G  G+ G  G 
Sbjct: 945  EPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGP 1004

Query: 456  PGPKGSAGNPGEPGLRGPEGSR------GLPGVEGPRGPPGPRGVQGEQGATGLPGVQGP 509
            PGPKG+ G PG+PGL GP G +      G PG +G  GPPGP GV G+ G+ GLPG +G 
Sbjct: 1005 PGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGD 1064

Query: 510  PGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQ 569
             G                             P   + GLPG PGP G PG PG  G PG 
Sbjct: 1065 KG----------------------------DPGISSIGLPGLPGPKGEPGLPGYPGNPGI 1096

Query: 570  MGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGPAS---- 624
             G  G PG+ G PG  G +G  G  G  G  GPPG +G +G PG  GLPG+PGP      
Sbjct: 1097 KGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGH 1156

Query: 625  YGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEP 660
             G+ G  GE+G PG  GIPG  G  G PG PGF  P
Sbjct: 1157 PGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNP 1192



 Score =  506 bits (1302), Expect = e-143
 Identities = 328/811 (40%), Positives = 378/811 (46%), Gaps = 190/811 (23%)

Query: 24  QRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADG 83
           +RG PG  G PG  GPPG PGI G+ G+ G       PGP G PG PG PG  G PG  G
Sbjct: 130 ERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTG 189

Query: 84  LTGPDGSPGSIGSKGQKGEPGVPGSRGFPG------------RGIPGPPGPP-------- 123
           + GP G PG  G  G  G PG+PG +G  G            +G+ GPPGPP        
Sbjct: 190 IPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKR 249

Query: 124 --------GTAGLPGELGRVGPVGDPGRRGPPGPP----------GPPGPRGTIG--FHD 163
                   G  GLPG+    GP G PG RGPPGPP          G PG RG  G    +
Sbjct: 250 PIDVEFQKGDQGLPGDR---GPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGEN 306

Query: 164 GDPLCPNACPPGRSGYPGLPGMRGHKGAKGE-------------------------IGEP 198
           G P  P    PG  GYPG PG  G KG KG+                         IG P
Sbjct: 307 GQPGIPGL--PGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLP 364

Query: 199 GRQGHKGEEGDQGELGEVGAQGPPGA--QGLRGITGIVGDKGEKGAR-----------GL 245
           G  G KGE G  G  G  G  GPPGA   G  G  G  G++G+KG             GL
Sbjct: 365 GLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGL 424

Query: 246 DGEPGPQGLPGAPGDQG----------QRGPPGEAGPKGDRGAEGARGI----------- 284
           DG+PG  GLPG PG  G          + GPPG  G  GD+G +G +G+           
Sbjct: 425 DGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNC 484

Query: 285 --PGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPG----- 337
              G+ GP G  GLPG+ G  G  G PG KGE G+ G  G  GL G+PG PG PG     
Sbjct: 485 IGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSK 544

Query: 338 --------AKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGP 389
                     G+ G+KG  G+PG PG  G  G PGQ G PG  GP+G  G    +GE GP
Sbjct: 545 GEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGP 604

Query: 390 VGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGE------PGPKGEQGAS----G 439
            G+PGLPG  G++G  G PG  GPPG  G KG +GV G       PGPKG+ G +    G
Sbjct: 605 PGNPGLPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPG 663

Query: 440 EEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQG 499
           + G  G  G  GD+GLPG  G  G PG PG+ G +G  G+PG+ G  GPPGP+       
Sbjct: 664 KPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGI-GLPGPPGPK------- 715

Query: 500 ATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPG--------R 551
             G PG+ GPPG   T   I                  L+ P  G  G PG         
Sbjct: 716 --GFPGIPGPPGAPGTPGRI-----------------GLEGP-PGPPGFPGPKGEPGFAL 755

Query: 552 PGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGAL---GLRGPKGDLGEKGERGPPG---- 604
           PGPPGPPG PG  G  G  G RG PG  GPPG     GL GPKGD+G  G+ GP G    
Sbjct: 756 PGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGL 815

Query: 605 --------RGPNGLPGAIGLP---------GDPGPASYGRNGRDGERGPPGVAGIPGVPG 647
                    GP G+PG IG P         GDPGP      G  GERG PG+ G PG  G
Sbjct: 816 PGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIG 875

Query: 648 PPGPPGLPGFCEPASCTMQAGQRAFNKGPDP 678
           PPG PGLPG    +      G+      P P
Sbjct: 876 PPGSPGLPGKAGASGFPGTKGEMGMMGPPGP 906



 Score =  503 bits (1294), Expect = e-142
 Identities = 316/726 (43%), Positives = 373/726 (51%), Gaps = 83/726 (11%)

Query: 19   CLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGT 78
            C+     GPPG+ G PG PGPPG  G  G  G++G  G  GP G  G PG PGAPG PG+
Sbjct: 484  CIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGS 543

Query: 79   PGADG----LTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR-GIPGPPG------------ 121
             G  G      G  G  G +GS G  G PG+PG+ G  G  G+PGP G            
Sbjct: 544  KGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERG 603

Query: 122  PPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNA--------CP 173
            PPG  GLPG  G +GP+G PG  GPPGP G  G +G  G + G P  P            
Sbjct: 604  PPGNPGLPGLPGNIGPMGPPGF-GPPGPVGEKGIQGVAG-NPGQPGIPGPKGDPGQTITQ 661

Query: 174  PGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELG--EVGAQGPPGAQGLRGIT 231
            PG+ G PG PG  G  G  G+ G PG+ G  G  G +GE G   +G  GPPG +G  GI 
Sbjct: 662  PGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIP 721

Query: 232  GIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQR--GPPGEAGPKGDRGAEGARGIPGLPG 289
            G  G  G  G  GL+G PGP G PG  G+ G    GPPG  G  G +GA G +G  G PG
Sbjct: 722  GPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPG 781

Query: 290  PKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPG--DAGLQGLPGVPGIPGA------KGV 341
            P G  G  G+DG  G  G  G  G+PG  GPPG    G+QG PG PGIPG        G+
Sbjct: 782  PPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGI 841

Query: 342  AGEKGSTGAPGK--PGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKL 399
             GEKG  G PG   PG  G  G PG  G PG +GP G  GLPG  G  G  G+ G  G +
Sbjct: 842  PGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMM 901

Query: 400  GSLGSPGLPGLPGPPGLPGMKGDRGVVGEPG---PKGEQGASGEEGEAGERGELGD--IG 454
            G  G PG  G+PG  G+PG+KGD G+ G+PG   P GE+G+ GE G  G  G +    +G
Sbjct: 902  GPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLG 961

Query: 455  LPGPKGSAGNPGEPGLRGPEGSRGLPG------VEGPRGPPGPRGVQGEQGATGLPGVQG 508
              G KG  G PG PG+ GP+G +GLPG      + G  G PGP G +G  G  G PG+ G
Sbjct: 962  SKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIG 1021

Query: 509  PPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPG 568
            PPG   T           I +        ++ P  G +G+PG+PG PG PG  G+ G PG
Sbjct: 1022 PPGLKGT-----------IGDMGFPGPQGVEGPP-GPSGVPGQPGSPGLPGQKGDKGDPG 1069

Query: 569  QMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR-GPNGLPGAIGLPGDPG-PASYG 626
               I GLPG+ GP G  GL G  G+ G KG  G PG  G  G PGA G PG PG P + G
Sbjct: 1070 ISSI-GLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPG 1128

Query: 627  RNGRDGERGPPGVAGIPGVPGP---------PGP------PGLPGFCEPASCTMQAGQRA 671
              G  G  GPPG  G+PG PGP         PGP      PG  G   PA    + GQ  
Sbjct: 1129 PPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPG 1188

Query: 672  F-NKGP 676
            F N GP
Sbjct: 1189 FGNPGP 1194



 Score =  496 bits (1276), Expect = e-140
 Identities = 329/786 (41%), Positives = 376/786 (47%), Gaps = 162/786 (20%)

Query: 26  GPPGEQGPPGPPGPPGVPGIDGID--------GDRGPKGPPGPPGPAGEPGKP------- 70
           GPPG  GPPGPPG PG  G  G++        G++G +GPPGPPG   E  +P       
Sbjct: 198 GPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQK 257

Query: 71  ---GAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR----GIPGPPGPP 123
              G PG  G PG  G+ GP G PG  G KG+KGE G PG RG PG+    G PG PG P
Sbjct: 258 GDQGLPGDRGPPGPPGIRGPPGPPG--GEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLP 315

Query: 124 GTAGLPGELGRVGPVGDPGRRGPPGPPGP----------------------PGPRGTIGF 161
           G  G PGE GR G  G  G  GPPGPPG                       PG +G  GF
Sbjct: 316 GDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGF 375

Query: 162 HD-----GDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIG-----------EPGRQGHKG 205
                  G P  P A   G  G PG PG RG KG +G  G           +PG  G  G
Sbjct: 376 PGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPG 435

Query: 206 EEGDQG-------ELGEVGAQGPPGAQGLRGITGIVGDKGEKG-------ARGLDGEPGP 251
             G  G       E+ E G  GPPG+ G +G+ G  G KG+KG         G+ G PG 
Sbjct: 436 PPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495

Query: 252 QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDG----IPG 307
            GLPG PG  G  G PG+ G KG  GA G +G+PG+PG  G  G PG  G  G     PG
Sbjct: 496 PGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPG 555

Query: 308 MPGTKGEPGKPGPPGDAGLQGLPG---VPGIPGAKG------VAGEKGSTGAPGKPGQMG 358
           M G KGE G PG PG  GL G PG   +PG+PG KG        GE+G  G PG PG  G
Sbjct: 556 MKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPG 615

Query: 359 NSGKPGQQG--PPGEVGPRGPQG---------LPGSRGELGPV----GSPGLPGK----- 398
           N G  G  G  PPG VG +G QG         +PG +G+ G      G PGLPG      
Sbjct: 616 NIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDG 675

Query: 399 -LGSLGSPGLPGLPGPPGLPGMKGDRGV--VGEPGPKGEQGASGEEGEAGERGELGDIGL 455
            +G  G PGLPG PG PG+PG KG+ G+  +G PGP G +G  G  G  G  G  G IGL
Sbjct: 676 DVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGL 735

Query: 456 PGPKGSAGNPGEPGLRGPEGSRG--LPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRA 513
            GP      PG PG  GP+G  G  LPG  GP G PG +G  G +G  G PG  GPPGR 
Sbjct: 736 EGP------PGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRT 789

Query: 514 PTDQHIKQVCMRVIQEHFAEMAASLKRP--DSGATGLPGRPGPPG--------PPGPPGE 563
             D                     L  P  D G  G PG  GPPG        PPGPPG 
Sbjct: 790 GLD--------------------GLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGI 829

Query: 564 NGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR-GPNGLPGAIGLPGDPG- 621
            G  GQ G+ G+PG KG PG  GL  P G  GE+G  G PG  GP G PG+ GLPG  G 
Sbjct: 830 PGPIGQPGLHGIPGEKGDPGPPGLDVP-GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGA 888

Query: 622 ---PASYGRNGRDGERGPPGV------AGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAF 672
              P + G  G  G  GPPG       +G+PG+ G  G  G PG   P       G+   
Sbjct: 889 SGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGL 948

Query: 673 NKGPDP 678
              P P
Sbjct: 949 PGPPGP 954



 Score =  467 bits (1201), Expect = e-131
 Identities = 286/649 (44%), Positives = 331/649 (51%), Gaps = 115/649 (17%)

Query: 26   GPPGEQGPPG---PPGP------PGVP------GIDGIDGDRGPKGPPGPPGPAGEPGKP 70
            GPPGE+G PG    PGP      PG+P      G  G  G+ G  GPPGPPGP G PG+ 
Sbjct: 857  GPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRS 916

Query: 71   GAP---------GKPGTPGADGLTGPDGSPG-----------SIGSKGQKGEPGVPGSRG 110
            G P         G+PG PG  G  G  G PG            +GSKG+KGEPG+PG  G
Sbjct: 917  GVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPG 976

Query: 111  FPG----RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFH---- 162
              G    +G+PG PG PG +G PG  G  GP G+PG  G PG  GPPG +GTIG      
Sbjct: 977  VSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPG 1036

Query: 163  ----DGDPLCPNACPPGRSGYPGLPGMRGHK--------------GAKGEIGEPGRQGHK 204
                +G P  P+   PG+ G PGLPG +G K              G KGE G PG  G+ 
Sbjct: 1037 PQGVEGPP-GPSGV-PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNP 1094

Query: 205  GEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQR 264
            G +G  G+ G  G  G PGA+G  G+ G  G  G  G +G+ G PG  GLPG PG  G  
Sbjct: 1095 GIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGG 1154

Query: 265  GPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGV--DGRDGIPGMPGTKGEPGKPGPPG 322
            G PG+ GP G++G  G  GIPG  G KG+ G PG    G  G+PG+ G KG+ G PG PG
Sbjct: 1155 GHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPG 1214

Query: 323  DAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPG 382
            + GL G  G PG  G  GV G  G  G+PG P   G  G PG QGPPG  GP G QGLP 
Sbjct: 1215 NPGLPGPKGEPGFHGFPGVQGPPGPPGSPG-PALEGPKGNPGPQGPPGRPGPTGFQGLP- 1272

Query: 383  SRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEG 442
                 GP G PGLPG  G  G  G PG PG PGLPG+KGD+G  G  G  G  G +G +G
Sbjct: 1273 -----GPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKG 1327

Query: 443  EAGERGELGDIGLPGPK---GSAGNPGEPGLRGPEGSRGLPGVEGP----RGPPGPRGVQ 495
            + G  G  G  G+ GP    GSAG  GEPGL GP G  GLPG  G     +G  GP G+ 
Sbjct: 1328 DPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIP 1387

Query: 496  GEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPP 555
            G+ G  GLPG QGP G                                G TG      PP
Sbjct: 1388 GQPGLKGLPGPQGPQGL------------------------------PGPTG------PP 1411

Query: 556  GPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG 604
            G PG  G  GF G  G +G PG+ G PG  GL GP G  G +G  GPPG
Sbjct: 1412 GDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1460



 Score =  457 bits (1175), Expect = e-128
 Identities = 275/637 (43%), Positives = 321/637 (50%), Gaps = 121/637 (18%)

Query: 24   QRGPPGEQGPPGPPGPPGVPGIDG---------IDGDRGPKGPPGPPGPAGEPGKPGAPG 74
            +RG PG  G PGP GPPG PG+ G           G+ G  GPPGPPGP G PG+ G PG
Sbjct: 861  ERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPG 920

Query: 75   ---------KPGTPGADGLTGPDGSPGS-----------IGSKGQKGEPGVPGSRGFPG- 113
                     +PG PG  G  G  G PG            +GSKG+KGEPG+PG  G  G 
Sbjct: 921  LKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGP 980

Query: 114  ---RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFH-------- 162
               +G+PG PG PG +G PG  G  GP G+PG  G PG  GPPG +GTIG          
Sbjct: 981  KGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGV 1040

Query: 163  DGDPLCPNACPPGRSGYPGLPGMRGHKG--------------AKGEIGEPGRQGHKGEEG 208
            +G P  P+  P G+ G PGLPG +G KG               KGE G PG  G+ G +G
Sbjct: 1041 EGPP-GPSGVP-GQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKG 1098

Query: 209  DQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPG 268
              G+ G  G  G PGA+G  G+ G  G  G  G +G+ G PG  GLPG PG  G  G PG
Sbjct: 1099 SVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPG 1158

Query: 269  EAGPKGDRGAEGARGIPGLPGPKGDTGLPGVD--GRDGIPGMPGTKGEPGKPGPPGDAGL 326
            + GP G++G  G  GIPG  G KG+ G PG    G  G+PG+ G KG+ G PG PG+ GL
Sbjct: 1159 QPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGL 1218

Query: 327  QGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPG---- 382
             G  G PG  G  GV G  G  G+PG P   G  G PG QGPPG  GP G QGLPG    
Sbjct: 1219 PGPKGEPGFHGFPGVQGPPGPPGSPG-PALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGP 1277

Query: 383  -----------SRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPG- 430
                        +G  G  G PGLPG  G  G PGL G PG PGL GMKGD G+ G PG 
Sbjct: 1278 PGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGF 1337

Query: 431  -----PKGEQGASGEEGEAGERGELGDIGLPGPKGSA----GNPGEPGLRGPEGSRGLPG 481
                 P G  G++G EGE G  G  G  GLPGP G +    G+ G PG+ G  G +GLPG
Sbjct: 1338 PGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPG 1397

Query: 482  VEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRP 541
             +GP+G PGP G  G+ G  GLPG  G  GR                             
Sbjct: 1398 PQGPQGLPGPTGPPGDPGRNGLPGFDGAGGR----------------------------- 1428

Query: 542  DSGATGLPGRP------GPPGPPGPPGENGFPGQMGI 572
              G  GLPG+P      GPPGP G  G  G PG   +
Sbjct: 1429 -KGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPGTSSV 1464



 Score =  426 bits (1096), Expect = e-119
 Identities = 278/656 (42%), Positives = 312/656 (47%), Gaps = 145/656 (22%)

Query: 90  SPGS----IGSKGQKGEPGVPGSRGFPGR-GIPGPPGPPGTAGLPGELGRVGPVGDPGRR 144
           SPGS     G KG+KGE G PG  G PG  G PGP GPPG  G  G+ G  GP G  G R
Sbjct: 33  SPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKGIR 92

Query: 145 GPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHK 204
           GPPG PG PG                         PGLPGM GH GA G  G PG  G K
Sbjct: 93  GPPGLPGFPGT------------------------PGLPGMPGHDGAPGPQGIPGCNGTK 128

Query: 205 GEEGDQGELGEVGAQGPPGAQGLRGITGIVGD------KGEKGARGLDGEPGPQGLPGAP 258
           GE G  G  G  G QGPPG  G+ G+ G  G        G KG  G  G PG QGLPG  
Sbjct: 129 GERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPT 188

Query: 259 GDQGQRGPPGE-----------------------AGPKGDRGAEGARGIPGLPG------ 289
           G  G  GPPG                         GPKG++G +G +G PG PG      
Sbjct: 189 GIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQK 248

Query: 290 -------PKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVA 342
                   KGD GLPG  G  G PG+ G  G PG  G  G+ G QG PG  G PG  G  
Sbjct: 249 RPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPG--GEKGEKGEQGEPGKRGKPGKDGEN 306

Query: 343 GEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGL----PGSRGELGPVGSPGLPGK 398
           G+ G  G PG PG  G  G+ G++G  G+ GP GP GL    PG+   +G  G+ GLPG 
Sbjct: 307 GQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGL 366

Query: 399 LGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGP 458
            G  G  G PG+ GPPGLPG  G   V+G PGP G  G  G++G+ G  G    I +PGP
Sbjct: 367 PGEKGERGFPGIQGPPGLPGPPG-AAVMGPPGPPGFPGERGQKGDEGPPG----ISIPGP 421

Query: 459 KGSAGNPGEPGLRGPEGSRG----------LPGVEGPRGPPGPRGVQGEQGATGLPGVQG 508
            G  G PG PGL GP G  G           PG  GP G PG +G+QGEQG  G  G   
Sbjct: 422 PGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKG--- 478

Query: 509 PPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPG 568
                         C   I               +G +G PG+PG PG PGPPG  GFPG
Sbjct: 479 ------------DTCFNCI--------------GTGISGPPGQPGLPGLPGPPGSLGFPG 512

Query: 569 Q---------MGIRGLPGIKGPPGALGLRGPKGD----------LGEKGERGPPGR---- 605
           Q          G +GLPGI G PGA G  G KG+           G+KGE G PG     
Sbjct: 513 QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572

Query: 606 GPNGLPGAIGLPGDPGP-ASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEP 660
           G  G PG  GLPG PGP    G     GERGPPG  G+PG+PG  GP G PGF  P
Sbjct: 573 GLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPP 628



 Score =  283 bits (724), Expect = 4e-76
 Identities = 165/358 (46%), Positives = 189/358 (52%), Gaps = 40/358 (11%)

Query: 15   LLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPG 74
            L GL      +G PG  G PG PGPPG  GI G  G+ G  G PGP G  G PG+PG PG
Sbjct: 1105 LPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPG 1164

Query: 75   KPGTPGADGLTGPDGS--------------PGSIGSKGQKGEPGVPGSRGFPGRGIPGPP 120
            + G PG DG+ GP G               PG  G  GQKG+ G+PG  G PG  +PGP 
Sbjct: 1165 EKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPG--LPGPK 1222

Query: 121  GPPGTAGLPGELGRVGPVGDPGR-----RGPPGPPGPPGPRGTIGFH-----DGDPLCP- 169
            G PG  G PG  G  GP G PG      +G PGP GPPG  G  GF      +G P  P 
Sbjct: 1223 GEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPG 1282

Query: 170  NACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRG 229
            N    G  G PG PG+ G  G KG+ G PG QG+ G  G  G  G+ G  G PG  G++G
Sbjct: 1283 NGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKG 1342

Query: 230  ITGIVGDKGEKGARGLDGEPGPQGLPGAPG-------DQGQRGPPGEAGPKGDRGAEGAR 282
             +G+ G  G +G  GL G PGP GLPG  G       D G  G PG+ G KG  G +G +
Sbjct: 1343 PSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQ 1402

Query: 283  GIPGLPGPKGD---TGLPGVD---GRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPG 334
            G+PG  GP GD    GLPG D   GR G PG+PG  G  G  GPPG  GLQG PG PG
Sbjct: 1403 GLPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1460


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score =  552 bits (1422), Expect = e-157
 Identities = 313/678 (46%), Positives = 365/678 (53%), Gaps = 51/678 (7%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGP------PGPPGPAGEPGKPGAPGKPGT- 78
            G PG  GPPG  G PG+ G  G DG+RG KG       PGP GP G+PG PG PG PG  
Sbjct: 407  GAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKG 466

Query: 79   -PGADGLTGPDGSPGSIGSKGQKGEPGV---PGSRGFPGRGIPGPPGPPGTAGLPGELGR 134
              G  GL G  G PG +G+KG +G PG+   PGSRG PG G+ GPPGP G          
Sbjct: 467  KDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPP-------- 518

Query: 135  VGPVGDPGRRGPPGPPGPPGPRGTIGFHD----GD------PLCPNACPPGRSGYPGLPG 184
             G  G PG RG PG PGP GP G  G       GD       +C N CPPG  G PGLPG
Sbjct: 519  -GDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVC-NDCPPGPPGLPGLPG 576

Query: 185  MRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARG 244
             +G KG  G+ G  G +G KGE G  G  G  G  GP G+QG RG  G VG KG++G  G
Sbjct: 577  FKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPG 636

Query: 245  LDGEPGPQGLPGAPGDQ---GQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDG 301
            + G  GP G PG PG     G  GPPG  G  G  G  G +G  GLPG  G+ G  G DG
Sbjct: 637  VPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDG 696

Query: 302  RDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGK---PGQMG 358
            + G PG PG  GEPG PGP G  G  G  G  G  GA G  GE G+ G PG+   PG+ G
Sbjct: 697  KPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDG 756

Query: 359  NSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPG 418
            ++G  G QGP G  GP G  G PGS GE GP G+PG  G  G  GSPGLPG  GP G PG
Sbjct: 757  DTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPG 816

Query: 419  MKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPE---G 475
              G++GV G+ G  G+ G  G +GE G+ G  GD G PG KG  G+PG PG +G     G
Sbjct: 817  EPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMG 876

Query: 476  SRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMA 535
             +GLPG  GP GPPGP          G PG  G  G +P+ + ++++    + +      
Sbjct: 877  PQGLPGENGPVGPPGP---------PGQPGFPGLRGESPSMETLRRLIQEELGKQLETRL 927

Query: 536  ASL--KRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGD 593
            A L  + P +      GRPGPPGPPG  G  G  G MG  G PG  G  G  G  GPKG+
Sbjct: 928  AYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGE 987

Query: 594  LGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPG 653
             G KG+ G PG G  G  G  G+PG PG   Y ++G  G  GP G  G  G PG PGPPG
Sbjct: 988  RGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPG 1047

Query: 654  LPGFCEPASCTMQAGQRA 671
             PG C+P+ C   A   A
Sbjct: 1048 PPGQCDPSQCAYFASLAA 1065



 Score =  503 bits (1295), Expect = e-142
 Identities = 299/702 (42%), Positives = 351/702 (50%), Gaps = 100/702 (14%)

Query: 19  CLCAAQRGPP-----GEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAP 73
           C+ AA+  P      GE G  G  G PG PG+ G  G++G  G PG  G AG PG PG P
Sbjct: 235 CILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFP 294

Query: 74  GKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR--------GIPGPPGPPGT 125
           G  G  G  G  G  G PG  G +G+KGE G  G  G PG          +PG  GP G 
Sbjct: 295 GVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGE 354

Query: 126 AGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGM 185
            G PG  G  G  G PG  GP GP GPPG +G  G H       N   PG  G PG  G 
Sbjct: 355 KGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGP 414

Query: 186 RGHKGAKGEIGEPGRQGHKGEE---GDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGA 242
            G  GA G  G PG+ G +GE+   G++G  G VG +G PGA GL G  G  G  GE G 
Sbjct: 415 PGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPGL 473

Query: 243 RGLDGEPGP------QGLPGAPGDQGQR--------GPPGEAGPKGDRGAEGARGIPGLP 288
           RG  G PGP      +G PG PG  G R        GPPG +GP GD+G+ G+RG+PG P
Sbjct: 474 RGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFP 533

Query: 289 GPKGDTGLPGVD---------------------GRDGIPGMPGTKGEPGKPGPP------ 321
           GP+G  G  G+                      G  G+PG+PG KG+ G PG P      
Sbjct: 534 GPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTE 593

Query: 322 ---GDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQ 378
              G+AG  GLPG PGI G +G  GE+G+ G  G+ G  G+ G PG  GPPG  GP G  
Sbjct: 594 GKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGAD 653

Query: 379 GLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGAS 438
           G+ G+ G  G  GSPG  G  G  G  GLPG+PG  G  G  G  G  GEPG  GE G  
Sbjct: 654 GIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLP 713

Query: 439 GEEGEAGE---RGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQ 495
           G EG  G    +G  GD G PGP+G +G  G PG  G  G  G  G  GP+GP GPRG  
Sbjct: 714 GPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPP 773

Query: 496 GEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPP 555
           G+ G+ G PG  GP G  P  +  K                     ++G+ GLPG  GP 
Sbjct: 774 GKNGSPGSPGEPGPSG-TPGQKGSK--------------------GENGSPGLPGFLGPR 812

Query: 556 GPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIG 615
           GPPG PGE G PG+       G+ G PG  G +G +GD G KG++GP        PG  G
Sbjct: 813 GPPGEPGEKGVPGK------EGVPGKPGEPGFKGERGDPGIKGDKGP--------PGGKG 858

Query: 616 LPGDPG-PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
            PGDPG P   G  G  G +G PG  G  G PGPPG PG PG
Sbjct: 859 QPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPG 900



 Score =  496 bits (1278), Expect = e-140
 Identities = 305/755 (40%), Positives = 365/755 (48%), Gaps = 141/755 (18%)

Query: 26  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGP---PGPPGPAGEPGKPGAPGKPGTPGAD 82
           G PGE+G  G PG PG PG+ G  GD+G KG    PG  G  GE G+ G  G PG PG  
Sbjct: 277 GRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTT 336

Query: 83  GLTGPDGS-PGSIGSKGQKGEPGVPGSRGFPGR----GIPGPPGPPGTAGLPGELGRVGP 137
            L  P    PG  G KG+KG+PG+PG  G  GR    G  GP GPPG  G  G  G  G 
Sbjct: 337 SLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGA 396

Query: 138 VGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGE 197
            G+PG  G  G PGP GP G++G             PG  G PG  G RG KGA GE G 
Sbjct: 397 AGNPGAPGHVGAPGPSGPPGSVG------------APGLRGTPGKDGERGEKGAAGEEGS 444

Query: 198 PGRQGHKGEEGDQGELGEVGA--QGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLP 255
           PG  G +G+ G  G  G  G    G PG +G  G+ G +G KG++GA G+ G PG +G P
Sbjct: 445 PGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDP 504

Query: 256 GAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVD--------------- 300
           G     G  GPPG +GP GD+G+ G+RG+PG PGP+G  G  G+                
Sbjct: 505 GI----GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDV 560

Query: 301 ------GRDGIPGMPGTKGEPGKPGPPG---------DAGLQGLPGVPGIPGAKGVAGEK 345
                 G  G+PG+PG KG+ G PG PG         +AG  GLPG PGI G +G  GE+
Sbjct: 561 CNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGER 620

Query: 346 GSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSP 405
           G+ G  G+ G  G+ G PG  GPPG  GP G  G+ G+ G  G  GSPG  G  G  G  
Sbjct: 621 GADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPS 680

Query: 406 GLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGE---RGELGDIGLPGPKGSA 462
           GLPG+PG  G  G  G  G  GEPG  GE G  G EG  G    +G  GD G PGP+G +
Sbjct: 681 GLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGES 740

Query: 463 GNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQV 522
           G  G PG  G  G  G  G  GP+GP GPRG  G+ G+ G PG  GP G  P  +  K  
Sbjct: 741 GAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSG-TPGQKGSKG- 798

Query: 523 CMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPG---IK 579
                              ++G+ GLPG  GP GPPG PGE G PG+ G+ G PG    K
Sbjct: 799 -------------------ENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFK 839

Query: 580 GPPGALGLRGPKGDLGEKGERGPPG----------RGPNGLPGA---IGLPGDPG----- 621
           G  G  G++G KG  G KG+ G PG           GP GLPG    +G PG PG     
Sbjct: 840 GERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFP 899

Query: 622 -----------------------------------PASYGRN--GRDGERGPPGVAGIPG 644
                                              P +Y ++  GR G  GPPG  G+PG
Sbjct: 900 GLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPG 959

Query: 645 VPGP---PGPPGLPGFCEPASCTMQAGQRAFNKGP 676
             GP   PG PG  G   P+      G+R     P
Sbjct: 960 RAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDP 994



 Score =  437 bits (1124), Expect = e-122
 Identities = 266/620 (42%), Positives = 312/620 (50%), Gaps = 63/620 (10%)

Query: 61  PGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPP 120
           PG     G+PG  G+ G PG  GL G  G  G  G  G+KGE G+PG+ GFPG       
Sbjct: 243 PGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPG-----VR 297

Query: 121 GPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYP 180
           G  G  G  GELG  G  GD G +G  GP GPPG                  P   S + 
Sbjct: 298 GEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPG-----------------LPGTTSLFT 340

Query: 181 GLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEK 240
             P M G +G KGE G+PG  G  G +G  GELG  G  GPPGA+G  G  G  G  G  
Sbjct: 341 PHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNP 400

Query: 241 GARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVD 300
           GA G  G PGP G PG+ G  G RG PG+ G +G++GA G  G PG  GP+GD G PG+ 
Sbjct: 401 GAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLP 460

Query: 301 GRDGI--PGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMG 358
           G  G    G PG +G PG PGP G  G +G PG+PG PG++G  G  G  G PG  G  G
Sbjct: 461 GPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGI-GVAGPPGPSGPPG 519

Query: 359 NSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPG 418
           + G PG +G PG  GP+GP G  G    L P G   L  K      P  PG PG PGLPG
Sbjct: 520 DKGSPGSRGLPGFPGPQGPAGRDGLSSLLSP-GDINLLAKDVCNDCP--PGPPGLPGLPG 576

Query: 419 MKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRG 478
            KGD+GV G+PG +G +G  GE G  G  G  G  G  G +G  G  GE G +G +G  G
Sbjct: 577 FKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPG 636

Query: 479 LPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRA--PTDQHIKQVCMRVIQEHFAEMAA 536
           +PG  GP G PGP G  G  GA G PG+QG PG+   P  Q                   
Sbjct: 637 VPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQ------------------- 677

Query: 537 SLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGE 596
                  G +GLPG PG  G  G  G+ G PG+ G  G PG+ GP GA   RGP G  G 
Sbjct: 678 -------GPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGA---RGPPGFKGH 727

Query: 597 KGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
            G+ G PG  P G  GA+GLPG  G    G++G  G  GP G  G  G PG  G PG PG
Sbjct: 728 TGDSGAPG--PRGESGAMGLPGQEGLP--GKDGDTGPTGPQGPQGPRGPPGKNGSPGSPG 783

Query: 657 FCEPASCTMQAGQRAFNKGP 676
              P+    Q G +  N  P
Sbjct: 784 EPGPSGTPGQKGSKGENGSP 803



 Score =  339 bits (870), Expect = 4e-93
 Identities = 234/608 (38%), Positives = 287/608 (47%), Gaps = 133/608 (21%)

Query: 132 LGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGA 191
           L  +GP  DP      G  G  G   T        + P++  P  S    +P   GH+ +
Sbjct: 168 LDLLGPRTDPWENVDQGAQGACGRGNT-------SVLPSSVAPQCS----MPKGTGHEFS 216

Query: 192 KGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGP 251
                  G QG   +  D      + A+  PG + L G  G  G+ G  G  GL GE G 
Sbjct: 217 AAL----GTQGPADQRADARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGE 272

Query: 252 QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVD---------GR 302
           QGL G PG++G+ G PG  G  G RG +G +G       KG+ GLPG+          G 
Sbjct: 273 QGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQG------EKGELGLPGLKGDRGEKGEAGP 326

Query: 303 DGIPGMPGT----------------KGEPGKPGPPGDAGLQGLP------GVPGIPGAKG 340
            G PG+PGT                KGE G PG PG+ GLQG P      G  G PGAKG
Sbjct: 327 AGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKG 386

Query: 341 VAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLP---GSRGELGPVGSPGLPG 397
             G  G+ GA G PG  G+ G PG  GPPG VG  G +G P   G RGE G  G  G PG
Sbjct: 387 QEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPG 446

Query: 398 KLGSLGSPGLPGLPGPPGL-----PGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGD 452
            +G  G PG PGLPGPPG      PG++G  G+ G  G KG++GA G  G  G RG+ G 
Sbjct: 447 PVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPG- 505

Query: 453 IGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRG------------------------- 487
           IG+ GP G +G PG+   +G  GSRGLPG  GP+G                         
Sbjct: 506 IGVAGPPGPSGPPGD---KGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCN 562

Query: 488 --PPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGA 545
             PPGP G+ G  G  G  GV G PGR  T+                      K+ ++G 
Sbjct: 563 DCPPGPPGLPGLPGFKGDKGVPGKPGREGTEG---------------------KKGEAGP 601

Query: 546 TGLPGRPGPPGPPGPPGENGFPGQMGIR------GLPGIKGPP---------GALGLRGP 590
            GLPG PG  GP G  GE G  G++G +      G+PG  GPP         G  G  GP
Sbjct: 602 PGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGP 661

Query: 591 KGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPP 649
            G  G  G+ GPPG +GP+GLP   G+PG+ G    GR+G+ G  G PG AG PG+PGP 
Sbjct: 662 PGIQGSPGKEGPPGPQGPSGLP---GIPGEEG--KEGRDGKPGPPGEPGKAGEPGLPGPE 716

Query: 650 GPPGLPGF 657
           G  G PGF
Sbjct: 717 GARGPPGF 724



 Score =  289 bits (740), Expect = 5e-78
 Identities = 177/429 (41%), Positives = 207/429 (48%), Gaps = 81/429 (18%)

Query: 25   RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGL 84
            +G PG++GPPGP GP G+PGI G +G  G  G PGPP   GEPGK    G+PG PG +G 
Sbjct: 665  QGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPP---GEPGK---AGEPGLPGPEGA 718

Query: 85   TGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRR 144
             GP G  G  G  G  G  G  G+ G PG+   G PG  G  G  G  G  GP G PG+ 
Sbjct: 719  RGPPGFKGHTGDSGAPGPRGESGAMGLPGQ--EGLPGKDGDTGPTGPQGPQGPRGPPGKN 776

Query: 145  GPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHK 204
            G PG PG PGP GT G              G  G  G PG+ G  G +G  GEPG +G  
Sbjct: 777  GSPGSPGEPGPSGTPG------------QKGSKGENGSPGLPGFLGPRGPPGEPGEKGVP 824

Query: 205  GEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQR 264
            G+EG  G+ GE      PG +G RG  GI GDKG  G +G  G+PG  G  G  G  G +
Sbjct: 825  GKEGVPGKPGE------PGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQ 878

Query: 265  GPPGEAGPKGDRGAEGARGIPGLPG----------------------------------- 289
            G PGE GP G  G  G  G PGL G                                   
Sbjct: 879  GLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAY 938

Query: 290  ---PKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKG 346
                +G  G PG  G+DG+PG  G  GEPG+   PG  GL+G  G  G  G +G  G+ G
Sbjct: 939  MKSSQGRPGPPGPPGKDGLPGRAGPMGEPGR---PGQGGLEGPSGPIGPKGERGAKGDPG 995

Query: 347  STGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPG 406
            + G  G  G+MG  G PGQ G PG     G  G+PG +GE GP G PGLPG         
Sbjct: 996  APGV-GLRGEMGPPGIPGQPGEPG-YAKDGLPGIPGPQGETGPAGHPGLPGP-------- 1045

Query: 407  LPGLPGPPG 415
                PGPPG
Sbjct: 1046 ----PGPPG 1050



 Score =  258 bits (658), Expect = 2e-68
 Identities = 154/382 (40%), Positives = 174/382 (45%), Gaps = 53/382 (13%)

Query: 17   GLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKP 76
            GL     + G  G  G PGPPG PG  G  G+ G  G +GPPG  G  G+ G PG  G+ 
Sbjct: 681  GLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGES 740

Query: 77   GT---PGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELG 133
            G    PG +GL G DG  G  G +G +G  G PG  G PG   PG PGP GT G  G  G
Sbjct: 741  GAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGS--PGEPGPSGTPGQKGSKG 798

Query: 134  RVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKG 193
              G  G PG  GP GPPG PG +G  G             PG+ G PG  G RG  G KG
Sbjct: 799  ENGSPGLPGFLGPRGPPGEPGEKGVPG---------KEGVPGKPGEPGFKGERGDPGIKG 849

Query: 194  EIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGE----- 248
            + G PG +G  G+ G  G  G  G  GP G  G  G  G  G  G+ G  GL GE     
Sbjct: 850  DKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSME 909

Query: 249  ------------------------------PGPQGLPGAPGDQGQRGPPGEAGPKGDRGA 278
                                             QG PG PG  G+ G PG AGP G+ G 
Sbjct: 910  TLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGR 969

Query: 279  EGARGIPGLPGPKGDTGLPGVDGRDGIP--GMPGTKGEPGKPGPPGDAGL--QGLPGVPG 334
             G  G+ G  GP G  G  G  G  G P  G+ G  G PG PG PG+ G    GLPG+PG
Sbjct: 970  PGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPG 1029

Query: 335  IPGAKGVAGEKGSTGAPGKPGQ 356
              G  G AG  G  G PG PGQ
Sbjct: 1030 PQGETGPAGHPGLPGPPGPPGQ 1051



 Score =  227 bits (579), Expect = 2e-59
 Identities = 157/430 (36%), Positives = 189/430 (43%), Gaps = 49/430 (11%)

Query: 265 GPPGEAGPKGDRGAEGARG------IPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKP 318
           GP  +     D+GA+GA G      +P    P+    +P   G +    + GT+G   + 
Sbjct: 172 GPRTDPWENVDQGAQGACGRGNTSVLPSSVAPQ--CSMPKGTGHEFSAAL-GTQGPADQR 228

Query: 319 GPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPG---QMGNSGKPGQQGPPGEVGPR 375
                + +      PG+    G  GE+G  G PGKPG   ++G  G  G+ G  GE G  
Sbjct: 229 ADARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLP 288

Query: 376 GPQGLPGSRGELGPVGSPG---LPGKLGSLGSPGLPGLPGPPGLPGMKG----DRGVVGE 428
           G  G PG RGE G  G  G   LPG  G  G  G  G  GPPGLPG          + GE
Sbjct: 289 GAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGE 348

Query: 429 PGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGP 488
            GPKGE+G  G  GE G +G  G++G  GP G  G  G+ G  G  G+ G PG  G  G 
Sbjct: 349 QGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGA 408

Query: 489 PGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGL 548
           PGP G  G  GA GL G  G  G                     E  A+ +    G  G 
Sbjct: 409 PGPSGPPGSVGAPGLRGTPGKDGER------------------GEKGAAGEEGSPGPVGP 450

Query: 549 PGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPN 608
            G PG PG PGPPG+ G  G+ G+RG PG+ GP G  G RG  G  G  G RG PG G  
Sbjct: 451 RGDPGAPGLPGPPGK-GKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVA 509

Query: 609 GLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAG 668
           G PG  G PGD         G  G RG PG    PG  GP G  GL     P    + A 
Sbjct: 510 GPPGPSGPPGD--------KGSPGSRGLPG---FPGPQGPAGRDGLSSLLSPGDINLLAK 558

Query: 669 QRAFNKGPDP 678
               +  P P
Sbjct: 559 DVCNDCPPGP 568


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score =  548 bits (1411), Expect = e-156
 Identities = 338/800 (42%), Positives = 387/800 (48%), Gaps = 171/800 (21%)

Query: 12  GLLLLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGID------GDRGPKGPPGPP---- 61
           G+ + GL       GPPG  GPPG  G PG PG  G        G  GP GPPGPP    
Sbjct: 163 GVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIG 222

Query: 62  --GPA---GEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQ----------------- 99
             GPA   GE G+PG PG+ G PG  G+ GP G PG  G KG                  
Sbjct: 223 PSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPG 282

Query: 100 -KGEPGVPGSRGFPG-------------------------------RGIPGPPGPPGTAG 127
            KGE G+PG  G PG                                G PGPPGPPGTAG
Sbjct: 283 LKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAG 342

Query: 128 LPGE---LGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCP--NACPPGR-----S 177
            PG     G VGP G PG  G PG  G PGP+G  G   G P  P  N  P G+     +
Sbjct: 343 FPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAG-AQGPPGPPGINGSPGGKGEMGPA 401

Query: 178 GYPGLPGMRGHK------------GAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQ 225
           G PG PG+ G +            G +G  GEPG+ G KGE G +GE GE G  G PGA+
Sbjct: 402 GIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAK 461

Query: 226 ---------GLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDR 276
                    G  G  G+ G  GE+GA G  G  GP G+PG  G  G+RG PG AGP+G  
Sbjct: 462 GEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAA 521

Query: 277 GAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIP 336
           G  G  G+PG PG +G  G PG  G DG PG PG++GE G+PGPPG +G +G PGV G P
Sbjct: 522 GEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFP 581

Query: 337 GAK------GVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEV------------GPRGPQ 378
           G K      G  GE+G  G PG  G  G +G+ G QGPPG              GP+G Q
Sbjct: 582 GPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQ 641

Query: 379 GLPGSRGELGPVGSPGLPGKLGSLGSP---------GLPGLPGPPGLPGMKGDRGVVGEP 429
           GLPG+ G  G  G PG PG  G  G+P         G PG  GPPGL G  G RG  G P
Sbjct: 642 GLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPP 701

Query: 430 GPKGEQGASGEEGEAGER---------GELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLP 480
           GP+G +GA+G  G  G           GE G +G PGPKG  G PG PG  G  G  G  
Sbjct: 702 GPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPR 761

Query: 481 GVEGPRGPPGPRGV---QGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAAS 537
           G  GP GPPGP G    +GE GA GLPG+ GP G +P ++                    
Sbjct: 762 GPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRG-SPGERG------------------- 801

Query: 538 LKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEK 597
            +    G  G PG PG  G PG  GE G PG+ G  G PG+ GPPG  G  GP G  G K
Sbjct: 802 -ETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVK 860

Query: 598 GERGPP-GRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGP----- 651
           GERG P G G  G PGA GLPG P        G +G  GPPG +G PG  GPPGP     
Sbjct: 861 GERGSPGGPGAAGFPGARGLPGPP--------GSNGNPGPPGPSGSPGKDGPPGPAGNTG 912

Query: 652 -PGLPGFCEPASCTMQAGQR 670
            PG PG   P     Q G++
Sbjct: 913 APGSPGVSGPKGDAGQPGEK 932



 Score =  526 bits (1354), Expect = e-149
 Identities = 309/669 (46%), Positives = 343/669 (51%), Gaps = 60/669 (8%)

Query: 26   GPPGEQGP---PGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGAD 82
            GPPG QG    PGPPGP G  G  G+ G  GPKG  G PG  GE G PG PG  G PG +
Sbjct: 552  GPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKN 611

Query: 83   GLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----------RGIPGPPGPPGTAGLPGEL 132
            G TGP G PG  G  G KG+ G PG +G  G           G PG PGP G AG PG  
Sbjct: 612  GETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAP 671

Query: 133  GRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAK 192
            G  G  G PG RGPPG  G PG RG  G    +     A PPG  G  G PG++G  G +
Sbjct: 672  GGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGER 731

Query: 193  GEIGEPGRQGHKGEEGDQGE---LGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEP 249
            G +G PG +G KGE G  G     G+ G +GP G  G  G  G  GDKGE GA GL G  
Sbjct: 732  GGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIA 791

Query: 250  GPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGV------DGRD 303
            GP+G PG  G+ G  GP G  G  G  G  G +G  G PG KG+ G PGV       G  
Sbjct: 792  GPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPA 851

Query: 304  GIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKP 363
            G PG  G KGE G PG PG AG  G  G+PG PG+ G  G  G +G+PGK G  G +G  
Sbjct: 852  GPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNT 911

Query: 364  GQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDR 423
            G  G PG  GP+G  G PG +G  G  G PG PG LG  G  G  GL GPPG+PG    R
Sbjct: 912  GAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPG---PR 968

Query: 424  GVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVE 483
            G  G  G KGE G  G  G +GERG  G  GLPG  G+AG   EPG  G  GS GLPG +
Sbjct: 969  GSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAG---EPGRDGNPGSDGLPGRD 1025

Query: 484  GPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDS 543
            G  G  G RG  G  GA G PG  GPPG                         S  R +S
Sbjct: 1026 GSPGGKGDRGENGSPGAPGAPGHPGPPGPV------------------GPAGKSGDRGES 1067

Query: 544  GATGLPGRPGP------PGPPGPPGENGFPGQMGI------RGLPGIKGPPGALGLRGPK 591
            G  G  G PGP      PGP GP G+ G  G+ G       RG PG  G PG+ G  G +
Sbjct: 1068 GPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQ 1127

Query: 592  GDLGEKGERGPPGR-GPNGLPGAIGLPGDPGPASY-GRNGRDGERGPPGVAGIPGVPGPP 649
            G +G  G  GP G  GP+G PG  G  G PGP    G  G  GERG  G  G PG PGPP
Sbjct: 1128 GAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPP 1187

Query: 650  GPPGLPGFC 658
            GPPG PG C
Sbjct: 1188 GPPGAPGPC 1196



 Score =  525 bits (1353), Expect = e-149
 Identities = 327/727 (44%), Positives = 360/727 (49%), Gaps = 128/727 (17%)

Query: 24   QRGPPGEQG------PPGPPG------------PPGVPGIDGIDGDRGPKGP------PG 59
            QRG PG QG      PPGPPG            P G+PG  G+ G RGP GP      PG
Sbjct: 367  QRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPG 426

Query: 60   PPGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG------ 113
              G AGEPGK GA G+PG  G  G  G  G PG+ G  G+ G PG PG+ G PG      
Sbjct: 427  LRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERG 486

Query: 114  ----------RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGF-- 161
                       GIPG  GP G  G PG  G  G  G+PGR G PG PG  G  G+ G   
Sbjct: 487  APGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPG 546

Query: 162  HDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGA--- 218
             DG P  P +   G SG PG PG  G +G  G +G PG +G+ G  G  GE G  G    
Sbjct: 547  SDGKPGPPGS--QGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGP 604

Query: 219  QGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGD---QGQRGPPGEAGPKGD 275
            QGPPG  G  G  G  G  G  G +G  G PGPQGL G PG     G+ G PGE GPKGD
Sbjct: 605  QGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGD 664

Query: 276  RGAEGA------RGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGL 329
             GA GA       G PG  GP G  G PG+ G  G PG  G KG  G PGPPG AG  GL
Sbjct: 665  AGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGL 724

Query: 330  PGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGP 389
             G+PG  G  G  G KG  G PG PG  G  GK G +GP G +GP GP G PG +GE   
Sbjct: 725  QGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGE--- 781

Query: 390  VGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEA----- 444
             G+PGLPG  G  GSPG  G  GPPG  G  G  G  GEPG KGE+GA GE+GE      
Sbjct: 782  GGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGV 841

Query: 445  -------------GERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPP-- 489
                         G +G  G+ G PG  G+AG PG  GL GP GS G PG  GP G P  
Sbjct: 842  AGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGK 901

Query: 490  -GPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGL 548
             GP G  G  GA G PGV GP G A                              G  G 
Sbjct: 902  DGPPGPAGNTGAPGSPGVSGPKGDA---------------------------GQPGEKGS 934

Query: 549  PGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGE------KGERGP 602
            PG  GPPG PGP G  G  G  G+ G PG+ GP G+ G +G KG+ G+       GERGP
Sbjct: 935  PGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGP 994

Query: 603  PGRGPNGLPGAIGLPGDPG----PASYGRNGRD---------GERGPPGVAGIPGVPGPP 649
            P  GP GLPG  G  G+PG    P S G  GRD         GE G PG  G PG PGPP
Sbjct: 995  P--GPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPP 1052

Query: 650  GPPGLPG 656
            GP G  G
Sbjct: 1053 GPVGPAG 1059



 Score =  525 bits (1351), Expect = e-149
 Identities = 321/722 (44%), Positives = 359/722 (49%), Gaps = 103/722 (14%)

Query: 17   GLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKP 76
            GL   A  RG  G +G  G PGPPG PG  G  G  G KG  GP G  G  G PG  G+P
Sbjct: 312  GLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEP 371

Query: 77   GTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVG 136
            G  G  G  GP G PG  GS G KGE G  G  G P  G+ G  GPPG AG  G  G  G
Sbjct: 372  GPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAP--GLMGARGPPGPAGANGAPGLRG 429

Query: 137  PVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNA-------CPPGRSGYPGLPGMRGHK 189
              G+PG+ G  G PGP G RG  G     P  P A         PG  G  GLPG  G +
Sbjct: 430  GAGEPGKNGAKGEPGPRGERGEAGI----PGVPGAKGEDGKDGSPGEPGANGLPGAAGER 485

Query: 190  GAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEP 249
            GA G  G  G  G  GE+G  GE G  G  GP GA G  G  G+ G  G +G  G  G P
Sbjct: 486  GAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGP 545

Query: 250  GPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMP 309
            G  G PG PG QG+ G PG  GP G RG     G+ G PGPKG+ G PG +G  G PG P
Sbjct: 546  GSDGKPGPPGSQGESGRPGPPGPSGPRGQP---GVMGFPGPKGNDGAPGKNGERGGPGGP 602

Query: 310  GTKGEPGK---------------------PGPPGDAGLQGLPGVPGIPGAKGVAGE---K 345
            G +G PGK                      GPPG  GLQGLPG  G PG  G  GE   K
Sbjct: 603  GPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPK 662

Query: 346  GSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSP 405
            G  GAPG PG  G++G PG++GPPG        G PG RG  GP   PG  G  G+ G P
Sbjct: 663  GDAGAPGAPGGKGDAGAPGERGPPGLA------GAPGLRGGAGP---PGPEGGKGAAGPP 713

Query: 406  GLPGLPGPPGLPGMKGDRGVVGEPGPKGEQ------GASGEEGEAGERGELGDIGLPGPK 459
            G PG  G PGL GM G+RG +G PGPKG++      GA G  G+ G RG  G IG PGP 
Sbjct: 714  GPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPA 773

Query: 460  GSAGNPGE---PGLRGPEGSRGLPGVEGPRGPPGP------------------RGVQGEQ 498
            G  G+ GE   PGL G  G RG PG  G  GPPGP                  RG  GE+
Sbjct: 774  GQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEK 833

Query: 499  GATGLPGVQGPPGRA-----PTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPG 553
            G  G PGV GPPG +     P  Q +K                       GA GLPG PG
Sbjct: 834  GEGGPPGVAGPPGGSGPAGPPGPQGVK--------GERGSPGGPGAAGFPGARGLPGPPG 885

Query: 554  PPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPG 612
              G PGPPG +G PG+ G  G  G  G PG+ G+ GPKGD G+ GE+G PG +GP G PG
Sbjct: 886  SNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPG 945

Query: 613  AIGL------------PGDPGP-ASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCE 659
             +G+            PG PGP  S G  G  GE G PG  G+ G  GPPGP GLPG   
Sbjct: 946  PLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAG 1005

Query: 660  PA 661
             A
Sbjct: 1006 TA 1007



 Score =  521 bits (1341), Expect = e-147
 Identities = 319/711 (44%), Positives = 362/711 (50%), Gaps = 60/711 (8%)

Query: 17   GLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKP 76
            GL   A +RG PG +GP GP G   +PG  G  G+RG  GP GP G AGEPG+ G PG P
Sbjct: 477  GLPGAAGERGAPGFRGPAGPNG---IPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGP 533

Query: 77   GT---PGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR-GIPGPPGPPGTAGLPGEL 132
            G    PG+ G  G DG PG  GS+G+ G PG PG  G  G+ G+ G PGP G  G PG+ 
Sbjct: 534  GMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKN 593

Query: 133  GRVGPVGDPGRRGPPG------PPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMR 186
            G  G  G PG +GPPG      P GPPGP G  G   GD       PPG  G  GLPG  
Sbjct: 594  GERGGPGGPGPQGPPGKNGETGPQGPPGPTGP-GGDKGD-----TGPPGPQGLQGLPGTG 647

Query: 187  GHKGAKGEIGEPGRQGHKGEEGDQGELGEVGA---QGPPG---AQGLRGITGIVGDKGEK 240
            G  G  G+ GEPG +G  G  G  G  G+ GA   +GPPG   A GLRG  G  G +G K
Sbjct: 648  GPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGK 707

Query: 241  GARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRG---AEGARGIPGLPGPKGDTGLP 297
            GA G  G PG  G PG  G  G+RG  G  GPKGD+G     GA G+PG  GP+G TG  
Sbjct: 708  GAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPI 767

Query: 298  GVDGRDGIPGMPGTKGEPGKPG------PPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAP 351
            G  G  G PG  G  G PG PG       PG+ G  G PG  G PGA G  GE G  G  
Sbjct: 768  GPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGER 827

Query: 352  GKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLP 411
            G PG+ G  G PG  GPPG  GP GP G  G +GE G  G PG  G  G+ G PG PG  
Sbjct: 828  GAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSN 887

Query: 412  GPPGLPGMKGDRGVVGEPGPKGEQGA------SGEEGEAGERGELGDIGLPGPKGSAGNP 465
            G PG PG  G  G  G PGP G  GA      SG +G+AG+ GE G  G  GP G+ G  
Sbjct: 888  GNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPL 947

Query: 466  GEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQG---ATGLPGVQGPPG---------RA 513
            G  G+ G  G  G PG+ GPRG PGP+GV+GE G   A GL G +GPPG          A
Sbjct: 948  GIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTA 1007

Query: 514  PTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGP------PGENGFP 567
                         +            R ++G+ G PG PG PGPPGP       G+ G  
Sbjct: 1008 GEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGES 1067

Query: 568  GQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGPASY- 625
            G  G  G PG  G  GA G +GP+GD GE GERG  G +G  G PG  G PG PGPA   
Sbjct: 1068 GPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQ 1127

Query: 626  GRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGP 676
            G  G  G  GP G  G  G PG  G  G PG   P       G+R     P
Sbjct: 1128 GAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSP 1178



 Score =  505 bits (1300), Expect = e-143
 Identities = 310/739 (41%), Positives = 360/739 (48%), Gaps = 127/739 (17%)

Query: 33  PPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGL-----TGP 87
           P  P  P   P   G  G +G  GPPG PG  G+PG PG PG PG+PG  G+     TGP
Sbjct: 89  PQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGP 148

Query: 88  DGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGELGRVG---PVGDPGR 143
                   S   K    V G  G+PG  G PGPPGPPGT+G PG  G  G   P G+PG+
Sbjct: 149 QNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQ 208

Query: 144 RGPPGPPGPPG---PRGTIGFHDGDPLCPNAC-------PPG---RSGYPGLPGMRGHKG 190
            GP GPPGPPG   P G  G  DG+   P          PPG    +G PG PGM+GH+G
Sbjct: 209 AGPSGPPGPPGAIGPSGPAG-KDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRG 267

Query: 191 ------AKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARG 244
                  KGE G PG +G  G  G+ G  G +G +G PG +G  G+ G  G +G  GARG
Sbjct: 268 FDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARG 327

Query: 245 LDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDG 304
            DG+PGP G PG  G  G  G  GE GP G  G+ GA G  G PGP+G  G  G  G  G
Sbjct: 328 SDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPG 387

Query: 305 IPGMPGTKGE------PGKP------GPPGDAGLQGLPGV-------------------- 332
           I G PG KGE      PG P      GPPG AG  G PG+                    
Sbjct: 388 INGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRG 447

Query: 333 ----PGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELG 388
                GIPG  G  GE G  G+PG+PG  G  G  G++G PG  GP GP G+PG +G  G
Sbjct: 448 ERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAG 507

Query: 389 PVGSPGLPGKLGSLGSPGLPGLPGPP---GLPGMKGDRGVVGEPGPKGEQGASGE---EG 442
             G+PG  G  G+ G PG  G+PG P   G+PG  G  G  G+PGP G QG SG     G
Sbjct: 508 ERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPG 567

Query: 443 EAGERGELGDIGLPGPKGSAGNPGE------PGLRGPEGSRGLPGVEGPRGPPGPRGVQG 496
            +G RG+ G +G PGPKG+ G PG+      PG  GP+G  G  G  GP+GPPGP G  G
Sbjct: 568 PSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGG 627

Query: 497 EQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGP-- 554
           ++G TG PG QG  G   T                            G  G PG PGP  
Sbjct: 628 DKGDTGPPGPQGLQGLPGTG------------------------GPPGENGKPGEPGPKG 663

Query: 555 -PGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPG 612
             G PG PG  G  G  G RG PG+ G PG  G  GP G  G KG  GPPG  G  G PG
Sbjct: 664 DAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPG 723

Query: 613 AIGLPGD----------------PGPASYGRNGRDGER------GPPGVAGIPGVPGPPG 650
             G+PG+                 GP + G  G+DG R      GPPG AG PG  G  G
Sbjct: 724 LQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGG 783

Query: 651 PPGLPGFCEPASCTMQAGQ 669
            PGLPG   P     + G+
Sbjct: 784 APGLPGIAGPRGSPGERGE 802



 Score =  471 bits (1213), Expect = e-133
 Identities = 291/668 (43%), Positives = 326/668 (48%), Gaps = 97/668 (14%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 85
            G  GE+G PG PGP G PG +G  G +GP GP GP G  G+ G PG  G  G PG  G  
Sbjct: 591  GKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPP 650

Query: 86   GPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRG 145
            G +G PG  G KG  G PG PG +G    G PG  GPPG AG PG  G  GP G  G +G
Sbjct: 651  GENGKPGEPGPKGDAGAPGAPGGKG--DAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKG 708

Query: 146  PPGPPGPPGPRGTIGFHD-----------------GDPLCPNAC-------PPGRSGYPG 181
              GPPGPPG  GT G                    G+P  P A        P G +G  G
Sbjct: 709  AAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIG 768

Query: 182  LPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKG 241
             PG  G  G KGE G PG  G  G  G  GE GE G  GP G  G  G  G  G KGE+G
Sbjct: 769  PPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERG 828

Query: 242  ARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDG 301
            A G  GE GP G+ G PG  G  GPPG  G KG+RG+ G  G  G PG +G   LPG  G
Sbjct: 829  APGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARG---LPGPPG 885

Query: 302  RDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAG---EKGSTGA---PGKPG 355
             +G PG PG  G PGK GPPG AG  G PG PG+ G KG AG   EKGS GA   PG PG
Sbjct: 886  SNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPG 945

Query: 356  QMGNSGKPGQQG---PPGEVGPRG---PQGLPGSRG---------ELGPVGSPGLPGKLG 400
             +G +G  G +G   PPG  GPRG   PQG+ G  G         E GP G  GLPG  G
Sbjct: 946  PLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAG 1005

Query: 401  SLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKG 460
            + G PG  G PG  GLPG  G  G  G+ G  G  GA G  G  G  G +G  G  G +G
Sbjct: 1006 TAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRG 1065

Query: 461  SAGNPGEPGLRGPEGSRGLPGVEGPRGPPGP---RGVQGEQGATGLPGVQGPPGR-APTD 516
             +G  G  G  GP GSRG PG +GPRG  G    RG  G +G  G PG  G PG   P  
Sbjct: 1066 ESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAG 1125

Query: 517  QHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLP 576
            Q                   ++  P  G  G  G  GP GPPG  G +G PG +      
Sbjct: 1126 QQ-----------------GAIGSP--GPAGPRGPVGPSGPPGKDGTSGHPGPI------ 1160

Query: 577  GIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGP 636
               GPP      GP+G+ GE+G  G PG    G PG  G PG PGP         G  G 
Sbjct: 1161 ---GPP------GPRGNRGERGSEGSPGH--PGQPGPPGPPGAPGPCC-------GGVGA 1202

Query: 637  PGVAGIPG 644
              +AGI G
Sbjct: 1203 AAIAGIGG 1210



 Score =  464 bits (1193), Expect = e-130
 Identities = 263/591 (44%), Positives = 299/591 (50%), Gaps = 77/591 (13%)

Query: 22   AAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGA 81
            A   G PG +G  G PG  G PG+ G  G RG  GPPGP G  G  G PG PG  GTPG 
Sbjct: 665  AGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGL 724

Query: 82   DGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----RGIPGPPGPPGTAGLPGELGRVGP 137
             G+ G  G  GS G KG KGEPG PG+ G PG    RG  GP GPPG AG PG+ G  G 
Sbjct: 725  QGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGA 784

Query: 138  VGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGE 197
             G PG  GP G PG  G  G               PPG +G+PG PG  G  G KGE G 
Sbjct: 785  PGLPGIAGPRGSPGERGETG---------------PPGPAGFPGAPGQNGEPGGKGERGA 829

Query: 198  PGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGA 257
            PG +G  G  G  G  G  G  GPPG QG++G  G  G  G  G  G  G PGP G  G 
Sbjct: 830  PGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGN 889

Query: 258  PGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGT------ 311
            PG  G  G PG+ GP G  G  GA G PG+ GPKGD G PG  G  G  G PG       
Sbjct: 890  PGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGI 949

Query: 312  ---------KGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGK 362
                      G PG PGP G  G QG+ G  G PGA G++GE+G  G  G PG  G +G+
Sbjct: 950  AGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGE 1009

Query: 363  PGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGD 422
            PG+ G PG  G  G  G PG +G+ G  GSPG P      G+PG PG PGP G  G  GD
Sbjct: 1010 PGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAP------GAPGHPGPPGPVGPAGKSGD 1063

Query: 423  R------GVVGEPGPKGEQGASGEEGEAGERGELGD---IGLPGPKGSAGNPGEPGLRGP 473
            R      G  G PGP G +GA G +G  G++GE G+    G+ G +G  GNPG PG  GP
Sbjct: 1064 RGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGP 1123

Query: 474  EGSRGL---PGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEH 530
             G +G    PG  GPRGP GP G  G+ G +G PG  GPPG                   
Sbjct: 1124 AGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRG---------------- 1167

Query: 531  FAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENG-FPGQMGIRGLPGIKG 580
                     R + G+ G PG PG PGPPGPPG  G   G +G   + GI G
Sbjct: 1168 --------NRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGG 1210



 Score =  419 bits (1078), Expect = e-117
 Identities = 243/568 (42%), Positives = 283/568 (49%), Gaps = 83/568 (14%)

Query: 17   GLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKP 76
            GL     +RG  G  GP G  G PG PG DG+ G  GP+GP GP GP G  G+PG  G+ 
Sbjct: 723  GLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEG 782

Query: 77   GTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR-GIPGPPGPPGTAGLPGELGRV 135
            G PG  G+ GP GSP      G++GE G PG  GFPG  G  G PG  G  G PGE G  
Sbjct: 783  GAPGLPGIAGPRGSP------GERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEG 836

Query: 136  GP---VGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAK 192
            GP    G PG  GP GPPGP G +G  G   G         PG +G+PG  G+ G  G+ 
Sbjct: 837  GPPGVAGPPGGSGPAGPPGPQGVKGERGSPGG---------PGAAGFPGARGLPGPPGSN 887

Query: 193  GEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQ 252
            G  G PG  G  G++G  G  G  GA G PG  G +G  G  G+KG  GA+G  G PGP 
Sbjct: 888  GNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPL 947

Query: 253  GLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTK 312
            G+ G  G +G  GPPG  GP+G  G +G +G  G PG  G +G  G  G  G+PG+ GT 
Sbjct: 948  GIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTA 1007

Query: 313  GEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEV 372
            GEPG+ G PG     GLPG  G PG KG  GE GS GAPG PG             PG  
Sbjct: 1008 GEPGRDGNPGS---DGLPGRDGSPGGKGDRGENGSPGAPGAPGH------------PGPP 1052

Query: 373  GPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPK 432
            GP GP G  G RGE GP G  G PG  GS G+PG  G  G  G  G +G  G+ G  G  
Sbjct: 1053 GPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFP 1112

Query: 433  GEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPR 492
            G  GA G  G AG++G +G  G  GP+G  G  G P   G +G+ G PG   P GPPGPR
Sbjct: 1113 GNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPP---GKDGTSGHPG---PIGPPGPR 1166

Query: 493  GVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRP 552
            G +GE+G+ G PG  G P                                          
Sbjct: 1167 GNRGERGSEGSPGHPGQP------------------------------------------ 1184

Query: 553  GPPGPPGPPGE-NGFPGQMGIRGLPGIK 579
            GPPGPPG PG   G  G   I G+ G K
Sbjct: 1185 GPPGPPGAPGPCCGGVGAAAIAGIGGEK 1212



 Score =  404 bits (1039), Expect = e-112
 Identities = 262/639 (41%), Positives = 298/639 (46%), Gaps = 107/639 (16%)

Query: 130 GELGRVGPVGDPGRRGPPGPPGPPGPRGTIG-----FHDGDPLCP--------------- 169
           GE   V P        PP   GP GP+G  G       +GDP  P               
Sbjct: 82  GECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGIC 141

Query: 170 NACPP---------------------GRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEG 208
            +CP                      G +GYPG  G  G  G  G  G PG  G  G +G
Sbjct: 142 ESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQG 201

Query: 209 DQGELGEVGAQGPPGAQGLRGITGIVGDKGEK------GARGLDGEP---GPQGLPGAPG 259
             GE G+ G  GPPG  G  G +G  G  GE       G RGL G P   GP G+PG PG
Sbjct: 202 PPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPG 261

Query: 260 DQGQRGPPGEAGPKGDRGAEGARGIPGL------PGPKGDTGLPGVDGRDGIPGM----- 308
            +G RG  G  G KG+ GA G +G  GL      PGP G  G PG  GR G+PG      
Sbjct: 262 MKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARG 321

Query: 309 -PGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQG 367
             G +G  G+PGPPG  G  G PG PG  G  G AG  GS GAPG+ G+ G  G  G QG
Sbjct: 322 NDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQG 381

Query: 368 PPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGD---RG 424
           PP   GP G  G PG +GE+GP G PG PG +G+ G PG  G  G PGL G  G+    G
Sbjct: 382 PP---GPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNG 438

Query: 425 VVGEPGPKGEQGASGEEGEAGERGELGDIGLPGP------KGSAGNPGEPGLRGPEGSRG 478
             GEPGP+GE+G +G  G  G +GE G  G PG        G+AG  G PG RGP G  G
Sbjct: 439 AKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNG 498

Query: 479 LPGVEGP---RGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMA 535
           +PG +GP   RG PGP G +G  G  G  GV G PG            MR +        
Sbjct: 499 IPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPG------------MRGMPGSPGGPG 546

Query: 536 ASLKRPDSGATGLPGRPGPPGPPGP---PGENGFPGQMGIRGLP---GIKGPPGALGLRG 589
           +  K    G+ G  GRPGPPGP GP   PG  GFPG  G  G P   G +G PG  G +G
Sbjct: 547 SDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQG 606

Query: 590 PKGDLGEKGERGPPG----------RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGV 639
           P G  GE G +GPPG           GP G  G  GLPG  GP   G NG+ GE GP G 
Sbjct: 607 PPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPP--GENGKPGEPGPKGD 664

Query: 640 AGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPDP 678
           AG PG PG  G  G PG   P       G R     P P
Sbjct: 665 AGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGP 703



 Score =  375 bits (963), Expect = e-104
 Identities = 229/559 (40%), Positives = 268/559 (47%), Gaps = 71/559 (12%)

Query: 155 PRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELG 214
           P   I F +   +CP   PP     P  P  +G +G KG+ G PG  G  G+ G  G+ G
Sbjct: 75  PNPEIPFGECCAVCPQ--PPTAPTRP--PNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPG 130

Query: 215 EVGAQGPPG--------------------AQGLRGITGIVGDKGEKGARGLDGEPGPQGL 254
             G+ GPPG                     +    + G+ G  G  G  G  G PG  G 
Sbjct: 131 SPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGH 190

Query: 255 PGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGE 314
           PG+PG  G +GPPGE G  G  G          PGP G  G  G  G+DG  G PG  GE
Sbjct: 191 PGSPGSPGYQGPPGEPGQAGPSGP---------PGPPGAIGPSGPAGKDGESGRPGRPGE 241

Query: 315 PGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGP 374
            G PGPPG  G  G+PG PG+ G +G  G  G  G  G PG  G +G PG+ G P   GP
Sbjct: 242 RGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAP---GP 298

Query: 375 RGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPP---GLPGMKGDRGVVGEPGP 431
            GP+G PG RG  G  G+ G  G  G+ GS G PG PGPP   G PG  G +G VG  G 
Sbjct: 299 MGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGS 358

Query: 432 KGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGP 491
            G  GA G+ GE G +G  G  G PGP G  G+PG  G  GP G  G PG+ G RGPPGP
Sbjct: 359 PGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGP 418

Query: 492 RGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLP-- 549
            G     GA GL G  G PG+                    E     +R ++G  G+P  
Sbjct: 419 AGA---NGAPGLRGGAGEPGKNGAK---------------GEPGPRGERGEAGIPGVPGA 460

Query: 550 -GRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGP 607
            G  G  G PG PG NG PG  G RG PG +GP G  G+ G KG  GE+G  GP G RG 
Sbjct: 461 KGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGA 520

Query: 608 NGLPGAIGLPGDPG----PASYGRNGRDGERGPPGVAGIPGVPGPPGP------PGLPGF 657
            G PG  G+PG PG    P S G  G DG+ GPPG  G  G PGPPGP      PG+ GF
Sbjct: 521 AGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGF 580

Query: 658 CEPASCTMQAGQRAFNKGP 676
             P       G+     GP
Sbjct: 581 PGPKGNDGAPGKNGERGGP 599



 Score =  219 bits (558), Expect = 7e-57
 Identities = 129/285 (45%), Positives = 147/285 (51%), Gaps = 28/285 (9%)

Query: 16   LGLCLCAAQRGPPGEQGPPGP---PGPPGV------PGIDGIDGDRGPKGPPGPPGPAGE 66
            LG+      RG  G  G PGP   PGP GV      PG +G+ G+RGP GP G PG AG 
Sbjct: 947  LGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGT 1006

Query: 67   PGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTA 126
             G+   PG+ G PG+DGL G DGSPG  G +G+ G PG PG+ G PG   PGP GP G +
Sbjct: 1007 AGE---PGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGP--PGPVGPAGKS 1061

Query: 127  GLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMR 186
            G  GE G  GP G PG  G  G PGP GPRG  G              G +G  G  G  
Sbjct: 1062 GDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKG---------ETGERGAAGIKGHRGFP 1112

Query: 187  GHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLD 246
            G+ GA G  G  G+QG  G  G  G  G VG  GPPG  G  G  G +G  G +G R   
Sbjct: 1113 GNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNR--- 1169

Query: 247  GEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPK 291
            GE G +G PG PG  G  GPPG  GP    G  GA  I G+ G K
Sbjct: 1170 GERGSEGSPGHPGQPGPPGPPGAPGP--CCGGVGAAAIAGIGGEK 1212



 Score =  155 bits (391), Expect = 2e-37
 Identities = 100/248 (40%), Positives = 112/248 (45%), Gaps = 32/248 (12%)

Query: 22   AAQRGPPGEQGPPG------------PPGPPGVPGIDGIDGDRGPKGP------PGPPGP 63
            + +RGPPG QG PG             PG  G+PG DG  G +G +G       PG PG 
Sbjct: 989  SGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGH 1048

Query: 64   AGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGP 122
             G PG  G  GK G  G  G  GP G+PG  GS+G  G  G  G +G  G RG  G  G 
Sbjct: 1049 PGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGH 1108

Query: 123  PGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGL 182
             G  G PG  G  GP G  G  G PGP GP GP G  G            PPG+ G  G 
Sbjct: 1109 RGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSG------------PPGKDGTSGH 1156

Query: 183  PGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGP-PGAQGLRGITGIVGDKGEKG 241
            PG  G  G +G  GE G +G  G  G  G  G  GA GP  G  G   I GI G+K    
Sbjct: 1157 PGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKAGGF 1216

Query: 242  ARGLDGEP 249
            A     EP
Sbjct: 1217 APYYGDEP 1224


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score =  544 bits (1402), Expect = e-155
 Identities = 319/701 (45%), Positives = 354/701 (50%), Gaps = 92/701 (13%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 85
            G PGE G PGPPGP G  G  G+ G  GPKG  G PG AGE G PGAPG  G PG DG T
Sbjct: 510  GAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGET 569

Query: 86   GPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRG 145
            G  G PG  G  G++GE G PG  GF  +G+PGPPGPPG  G PG+ G  G  G PG  G
Sbjct: 570  GAAGPPGPAGPAGERGEQGAPGPSGF--QGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVG 627

Query: 146  PPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKG 205
            P G  G PG RG+ G              G  G PG PG  G KGA G  G PG QG  G
Sbjct: 628  PRGERGFPGERGSPGAQGLQ---------GPRGLPGTPGTDGPKGASGPAGPPGAQGPPG 678

Query: 206  EEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRG 265
             +G  GE G  G  GP G +G  G  G  G  G+ G RGL G  GP G  GA G++G+ G
Sbjct: 679  LQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVG 738

Query: 266  PPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAG 325
            PPG AG  G RGA G RG  G PGP G  G PG DG+   PG  G +GE G+ G  G  G
Sbjct: 739  PPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQ---PGAKGEQGEAGQKGDAGAPG 795

Query: 326  LQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRG 385
             QG  G PG  G  GV G KG+ GA G PG  G  G  G+ GPPG  G  GP G PG  G
Sbjct: 796  PQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSG 855

Query: 386  ELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAG 445
            + GP G+ G  G  G  G PGL G  GPPG  G  GD G  G  GP G QG +G+ G  G
Sbjct: 856  KDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVG 915

Query: 446  ERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPG 505
              G+ G+ G PG  G +G PG+ G  G  G RG PG   P GPPG  G  GE G  G PG
Sbjct: 916  LPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPG---PVGPPGLTGPAGEPGREGSPG 972

Query: 506  VQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLK--RPDSGATGLPGRPGPPGPPGP--- 560
              GPPGR                    + AA +K  R ++GA G PG PGPPG PGP   
Sbjct: 973  ADGPPGR--------------------DGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGP 1012

Query: 561  ------------------------------------------PGENGFPGQMGIRGLPGI 578
                                                      PGE G  G  G  GL G+
Sbjct: 1013 TGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGL 1072

Query: 579  KGPPGALGLRGPKGDLGEKGERGPPGR-GPNGLPGAIGLPGDPGPASYGRNGRDGERGPP 637
             GPPG  G +G  G  G  G RGPPG  GP+G  GA G+PG  GP   G  GR GE GP 
Sbjct: 1073 PGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPP--GPRGRSGETGPA 1130

Query: 638  GVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPDP 678
            G  G PG PGPPGPPG PG       +  AG     KGPDP
Sbjct: 1131 GPPGNPGPPGPPGPPG-PGI----DMSAFAGLGPREKGPDP 1166



 Score =  526 bits (1354), Expect = e-149
 Identities = 311/703 (44%), Positives = 358/703 (50%), Gaps = 99/703 (14%)

Query: 26  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGK---------- 75
           GPPG  GP G PG PG PG  G  G  G +GP G  GP GEPG PG+PG           
Sbjct: 285 GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTD 344

Query: 76  -----------------PGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIP 117
                            PG PG  G  GP G+ G +G KGQ GEPG+ G +G  G +G P
Sbjct: 345 GIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP 404

Query: 118 GPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLC--------- 168
           GP GP G  G  GE G+ G  G+PG  GP GPPG  G  G  GF   D L          
Sbjct: 405 GPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGER 464

Query: 169 -PN--ACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQ 225
            P+  A P G +G PG PG  G  GA+G  G PG  G +G+ G  G  GE G  GPPG Q
Sbjct: 465 GPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQ 524

Query: 226 GLRGITGIVGDKGEKGA---------RGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDR 276
           G RG  G++G  G KGA         +GL G PG +GLPG  G+ G  GPPG AGP G+R
Sbjct: 525 GARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGER 584

Query: 277 GAEGA------RGIPGLPGPKGDTGLP---GVDGRDGIPGMPGTKGEPGKPGPPGDAGLQ 327
           G +GA      +G+PG PGP G+ G P   GV G  G PG+ G +GE G PG  G  G Q
Sbjct: 585 GEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQ 644

Query: 328 GLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGEL 387
           GL G  G+PG  G  G KG++G  G PG     G PG QG PGE G  G  G  G RG++
Sbjct: 645 GLQGPRGLPGTPGTDGPKGASGPAGPPGA---QGPPGLQGMPGERGAAGIAGPKGDRGDV 701

Query: 388 GPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGER 447
           G  G  G PGK    G  GL G  GPPG  G  G++G VG PGP G  GA G  GE GE 
Sbjct: 702 GEKGPEGAPGK---DGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGET 758

Query: 448 GELGDIGLPGPKGSAGNP---GEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLP 504
           G  G  G  GP G+ G P   GE G  G +G  G PG +GP G PGP+G  G  G  G  
Sbjct: 759 GPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGAR 818

Query: 505 GVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGEN 564
           G QGPPG         +V                     G  G  G PGPPGPPGP G++
Sbjct: 819 GAQGPPGATGFPGAAGRV---------------------GPPGSNGNPGPPGPPGPSGKD 857

Query: 565 GFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR----GPNGLP---GAIGLP 617
           G  G  G  G PG  G PG  G  GP G+ GE G+ GP G     GP GL    G +GLP
Sbjct: 858 GPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLP 917

Query: 618 GDPG----PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
           G  G    P   G +G  G++G PG +G  G PGP GPPGL G
Sbjct: 918 GQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTG 960



 Score =  513 bits (1321), Expect = e-145
 Identities = 302/697 (43%), Positives = 350/697 (50%), Gaps = 68/697 (9%)

Query: 24  QRGPPGE----QGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTP 79
           Q+G PG+     GP GPPGP G  G  G  GDRG KG  G PGP G  G+PG PG PG P
Sbjct: 36  QKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPP 95

Query: 80  GADGLTGPDGSPGSIGSKG---------------QKGEPGVPGSRGFPGRGIPGPPGPPG 124
           G  G  GP G  G+  ++                 +G  G  G RG PG    G PGP G
Sbjct: 96  GPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPA--GAPGPQG 153

Query: 125 TAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIG----FHDGDPLCPNACPPGRSGYP 180
             G PGE G  G  G  G RGPPGPPG PG  G  G      +  P  P     G  G P
Sbjct: 154 FQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGAR-GFPGTP 212

Query: 181 GLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEK 240
           GLPG++GH+G  G  G  G  G  G +G+ G  GE G+ GP G +GL G  G  G  G  
Sbjct: 213 GLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAA 272

Query: 241 GARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVD 300
           GARG DG+PGP G PG  G  G  G PG  G KG+ G  GARG  G  GP+G+ G PG  
Sbjct: 273 GARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSP 332

Query: 301 GRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNS 360
           G  G  G PGT G PG  G  G  G+ G PG PG  G  G  G  G  G  G+ G+ G +
Sbjct: 333 GPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIA 392

Query: 361 GKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMK 420
           G  G+QGP GE GP GPQG PG  GE G  G+ G PG +G +G PG  G PG  G PG  
Sbjct: 393 GFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQD 452

Query: 421 GDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLP 480
           G  G  G PG +G  G +G +G  G+ G  G+ GLPG +G  G PG+ G +G  G  G P
Sbjct: 453 GLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAP 512

Query: 481 GVEGPRGPPGPRGVQGEQGATGLP---GVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAAS 537
           G +G  GPPGP+G +G+ G  G P   G  G PG+A               E     A  
Sbjct: 513 GEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKA--------------GEKGLPGAPG 558

Query: 538 LK--RPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPP------------- 582
           L+      G TG  G PGP GP G  GE G PG  G +GLPG  GPP             
Sbjct: 559 LRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPG 618

Query: 583 --GALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVA 640
             GA GL GP+G+ G  GERG P  G  GL G  GLPG PG  + G  G  G  GPPG  
Sbjct: 619 EAGAPGLVGPRGERGFPGERGSP--GAQGLQGPRGLPGTPG--TDGPKGASGPAGPPGAQ 674

Query: 641 GIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPD 677
           G PG+ G PG  G  G   P       G+    KGP+
Sbjct: 675 GPPGLQGMPGERGAAGIAGPKGDRGDVGE----KGPE 707



 Score =  445 bits (1145), Expect = e-125
 Identities = 262/592 (44%), Positives = 294/592 (49%), Gaps = 78/592 (13%)

Query: 17   GLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKP 76
            GL     +RG PGE+G PG  G  G  G+ G  G  GPKG  GP GP G  G PG  G P
Sbjct: 624  GLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMP 683

Query: 77   GTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVG 136
            G  GA G+ GP G  G +G KG +G PG  G RG  G    GPPGP G  G  GE+G  G
Sbjct: 684  GERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGP--IGPPGPAGANGEKGEVGPPG 741

Query: 137  PVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIG 196
            P G  G RG PG  G  GP G  GF         A PPG  G PG  G +G  G KG+ G
Sbjct: 742  PAGSAGARGAPGERGETGPPGPAGF---------AGPPGADGQPGAKGEQGEAGQKGDAG 792

Query: 197  EPGRQGHKGEEGDQGELGEV------GAQGPPGAQGLRGITGIV---------------G 235
             PG QG  G  G QG  G        GAQGPPGA G  G  G V               G
Sbjct: 793  APGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG 852

Query: 236  DKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIP---GLPGPKG 292
              G+ G +G  G+ GP G  G PG QG  GPPGE G  GD G  GA G P   GL G +G
Sbjct: 853  PSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRG 912

Query: 293  DTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPG 352
              GLPG  G  G PG+PG  GEPGK G PG +G +G PG  G PG  G AGE      PG
Sbjct: 913  IVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGE------PG 966

Query: 353  KPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPG 412
            + G  G  G PG+ G  G  G RG  G  G+ G  GP GSPG  G  G  G  G  G  G
Sbjct: 967  REGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQG 1026

Query: 413  PPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRG 472
            P G  G  G RG+ G  GP+G++G +GE GE G +G  G  GL       G PG PG  G
Sbjct: 1027 PMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGL------QGLPGPPGPSG 1080

Query: 473  PEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFA 532
             +G+ G  G  GPRGPPGP G  G+ GA G+PG  GPPG                     
Sbjct: 1081 DQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRG------------------ 1122

Query: 533  EMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPG--QMGIRGL-PGIKGP 581
                  +  ++G  G PG PGPPGPPGPPG    PG       GL P  KGP
Sbjct: 1123 ------RSGETGPAGPPGNPGPPGPPGPPG----PGIDMSAFAGLGPREKGP 1164



 Score =  377 bits (968), Expect = e-104
 Identities = 230/562 (40%), Positives = 264/562 (46%), Gaps = 75/562 (13%)

Query: 120 PGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGY 179
           PGP G  G PG++  +         GP GPPGP GP G                      
Sbjct: 31  PGPKGQKGEPGDIKDIV--------GPKGPPGPQGPAGE--------------------- 61

Query: 180 PGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRG--ITGIVGDK 237
               G RG +G KGE G PG +G  GE G  G  G  G  GPPG  GL G     + G  
Sbjct: 62  ---QGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGF 118

Query: 238 GEK-GARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGL 296
            EK G   L    GP G  G  G  G  G PG  G +G+ G  G  G+ G  GP+G  G 
Sbjct: 119 DEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGP 178

Query: 297 PGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQ 356
           PG  G DG  G PG  GE G PGP G  G  G PG+PG+ G +G  G  G+ G  G PG 
Sbjct: 179 PGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGV 238

Query: 357 MGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGL 416
            G SG PG+ G PG   P GP+GLPG RG  GP G+ G  G  G  G  G PG  GP G 
Sbjct: 239 KGESGSPGENGSPG---PMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGG 295

Query: 417 PGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGS 476
           PG  G  G  GE GP G   A G EG  G RGE G  G PGP G++GNPG  G+ G +GS
Sbjct: 296 PGFPGAPGAKGEAGPTG---ARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGS 352

Query: 477 RGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAA 536
            G PG+ G  G PGPRG  G QGATG  G +G  G                         
Sbjct: 353 AGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTG------------------------- 387

Query: 537 SLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGE 596
                + G  G  G  GP G PGP G  G PG  G  G  G +G PG +G  GP G+ G 
Sbjct: 388 -----EPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGA 442

Query: 597 KGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
            G RG PG+  +GL G  G PG+ GP+  G  G  G  G PG  G PG+PG  G  G PG
Sbjct: 443 PGNRGFPGQ--DGLAGPKGAPGERGPS--GLAGPKGANGDPGRPGEPGLPGARGLTGRPG 498

Query: 657 FCEPASCTMQAGQRAFNKGPDP 678
              P      +G    +  P P
Sbjct: 499 DAGPQGKVGPSGAPGEDGRPGP 520



 Score =  209 bits (531), Expect = 9e-54
 Identities = 126/299 (42%), Positives = 142/299 (47%), Gaps = 59/299 (19%)

Query: 5    ARDRGALGLLLLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPG-- 62
            A  RG +GL          QRG  G  G PGP G PG  G  G  GDRGP GP GPPG  
Sbjct: 908  AGQRGIVGL--------PGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLT 959

Query: 63   -PAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPG 121
             PAGEPG+ G+PG  G PG DG  G  G  G  G+ G  G PG PGS        PGP G
Sbjct: 960  GPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGS--------PGPAG 1011

Query: 122  PPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPG 181
            P G  G  GE G  GP+G  G  G  G  GP GPRG                 G +G PG
Sbjct: 1012 PTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRG---------------DKGEAGEPG 1056

Query: 182  LPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKG 241
              G++GH+G  G  G PG  G  G++G  G  G  G +GPPG          VG  G+ G
Sbjct: 1057 ERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGP---------VGPSGKDG 1107

Query: 242  ARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVD 300
            A G+ G  GP G  G  G+ G  GPPG  GP            PG PGP G    PG+D
Sbjct: 1108 ANGIPGPIGPPGPRGRSGETGPAGPPGNPGP------------PGPPGPPG----PGID 1150


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score =  538 bits (1386), Expect = e-153
 Identities = 337/783 (43%), Positives = 382/783 (48%), Gaps = 134/783 (17%)

Query: 22   AAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGA 81
            A  +G  G +G PGP GP G PG  G +G RG +G PG  GP G PG+ GAPG  G PG 
Sbjct: 461  AGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQ 520

Query: 82   DGLTGPDGSP------------GSIGSKGQKGEPGVPGSRGFPGR--------------- 114
            DGL GP G+P            G+ G  G+ GEPG+PG+RG  GR               
Sbjct: 521  DGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGA 580

Query: 115  ----GIPGPPGPPGTAGLPGELGRVGPV---GDPGRRGPPGPPGPPGPRGTIGFHDGD-- 165
                G PGPPGP G  G PG +G  GP    G+PG+ G  G PG PG RG  G  DG+  
Sbjct: 581  PGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPG-KDGETG 639

Query: 166  ------PLCPNA--------CPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQG 211
                  P  P           P G  G PG PG  G  G  G+ G PG  G  G  G +G
Sbjct: 640  AAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRG 699

Query: 212  ELGEVGAQGPPGAQGL---RGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPG 268
            E G  G +G PGAQGL   RG+ G  G  G KGA G  G PG QG PG  G  G+RG  G
Sbjct: 700  ERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAG 759

Query: 269  EAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQG 328
             AGPKGDRG  G +G  G PG  G  GL G  G  G  G  G KGE G PGP G AG +G
Sbjct: 760  IAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARG 819

Query: 329  LPGVPGIPGAKGVAGEKGSTGAPGKP---------GQMGNSGKPGQQGPPGEVGPRGPQG 379
             PG  G  G  G AG  G  GA G+P         GQ G++G PG QGP G  GP+GP G
Sbjct: 820  APGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTG 879

Query: 380  L---PGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLP------GMKGDRGVVGEPG 430
            +    G+RG  GP G+ G PG  G +G PG  G PGPPG P      G KG RG  G PG
Sbjct: 880  VTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPG 939

Query: 431  PKGEQGASGEEGEAGERGELGD------IGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEG 484
              GE G  G  G  GE+GE GD       G PGP+G AG  G  GL G  G RG PG+ G
Sbjct: 940  RAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPG 999

Query: 485  PRGPPGPRGVQGEQGATGLPGVQGPPG-RAPTDQHIKQVCMRVIQEHFAEMAASLK--RP 541
            P G PG +G  G  G  G PG  GPPG   P  +  ++           + AA +K  R 
Sbjct: 1000 PSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRG 1059

Query: 542  DSGATGLPGRPGPPGPPGP----------------------------------------- 560
            ++GA G PG PGPPG PGP                                         
Sbjct: 1060 ETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKG 1119

Query: 561  ----PGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR-GPNGLPGAIG 615
                PGE G  G  G  GL G+ GPPG  G +G  G  G  G RGPPG  GP+G  GA G
Sbjct: 1120 EAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANG 1179

Query: 616  LPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKG 675
            +PG  GP   G  GR GE GP G  G PG PGPPGPPG PG       +  AG     KG
Sbjct: 1180 IPGPIGPP--GPRGRSGETGPAGPPGNPGPPGPPGPPG-PGI----DMSAFAGLGPREKG 1232

Query: 676  PDP 678
            PDP
Sbjct: 1233 PDP 1235



 Score =  527 bits (1358), Expect = e-149
 Identities = 330/751 (43%), Positives = 366/751 (48%), Gaps = 121/751 (16%)

Query: 25  RGPPGEQGPPGP------PGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKP-------- 70
           RGPPG  G PGP      PG PG PG+ G  G RGP GPPG PG  GE GKP        
Sbjct: 209 RGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGP 268

Query: 71  ----GAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTA 126
               GA G PGTPG  G+ G  G PG  G+KG+ G PGV G  G PG    G PGP G  
Sbjct: 269 PGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGEN--GSPGPMGPR 326

Query: 127 GLPGELGRVGPVGDPGRR------GPPGPPGPPGPRGTIGFHD----------------- 163
           GLPGE GR GP G  G R      GP GPPGP GP G  GF                   
Sbjct: 327 GLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPE 386

Query: 164 ------GDPLCP----------------------NACPPGRSGYPGLPGMRGHK------ 189
                 G+P  P                      +A  PG +G PG PG RG        
Sbjct: 387 GAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGAT 446

Query: 190 ---GAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPP---------GAQGLRGITGIVGDK 237
              G KG+ GEPG  G KGE+G +GE G  G QG P         GA+G  G  G +G  
Sbjct: 447 GPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPP 506

Query: 238 GEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLP 297
           GE+GA G  G PG  GL G  G  G+RGP G AGPKG  G  G  G PGLPG +G TG P
Sbjct: 507 GERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRP 566

Query: 298 GVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGV------AGEKGSTGAP 351
           G  G  G  G  G  GE G+PGPPG  G +G PGV G PG KG       AGEKG  GAP
Sbjct: 567 GDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAP 626

Query: 352 GKPGQMGNSGKPGQQGPPGEVGP---RGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLP 408
           G  G  G  G+ G  GPPG  GP   RG QG PG  G  G  G PG PG+ G  G  G+P
Sbjct: 627 GLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVP 686

Query: 409 GLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEP 468
           G  G PGL G +G+RG  GE G  G QG  G  G  G  G  G  G  GP G  G  G P
Sbjct: 687 GEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPP 746

Query: 469 GLRGPEGSRGLPGVEGPR------GPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQV 522
           GL+G  G RG  G+ GP+      G  GP G  G+ G  GL G  GPPG A  +    +V
Sbjct: 747 GLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEV 806

Query: 523 CMRVIQEHFAEMAASLKRPDSGATGLPGRPGPP---GPPGPPGENGFPGQMGIRGLPGIK 579
                        A  +R ++G  G  G  GPP   G PG  GE G  GQ G  G PG +
Sbjct: 807 GPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQ 866

Query: 580 GPPGALGLRGPKGDLGEKGER---GPPGR----------GPNGLPGAIGLPGDPGPASY- 625
           GP GA G +GP G  G KG R   GPPG           GP G  G  G PG PGP+   
Sbjct: 867 GPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKD 926

Query: 626 GRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
           G  G  G+ GPPG AG PG+ GP GPPG  G
Sbjct: 927 GPKGARGDSGPPGRAGEPGLQGPAGPPGEKG 957



 Score =  526 bits (1354), Expect = e-149
 Identities = 311/703 (44%), Positives = 358/703 (50%), Gaps = 99/703 (14%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGK---------- 75
            GPPG  GP G PG PG PG  G  G  G +GP G  GP GEPG PG+PG           
Sbjct: 354  GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTD 413

Query: 76   -----------------PGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIP 117
                             PG PG  G  GP G+ G +G KGQ GEPG+ G +G  G +G P
Sbjct: 414  GIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP 473

Query: 118  GPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLC--------- 168
            GP GP G  G  GE G+ G  G+PG  GP GPPG  G  G  GF   D L          
Sbjct: 474  GPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGER 533

Query: 169  -PN--ACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQ 225
             P+  A P G +G PG PG  G  GA+G  G PG  G +G+ G  G  GE G  GPPG Q
Sbjct: 534  GPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQ 593

Query: 226  GLRGITGIVGDKGEKGA---------RGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDR 276
            G RG  G++G  G KGA         +GL G PG +GLPG  G+ G  GPPG AGP G+R
Sbjct: 594  GARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGER 653

Query: 277  GAEGA------RGIPGLPGPKGDTGLP---GVDGRDGIPGMPGTKGEPGKPGPPGDAGLQ 327
            G +GA      +G+PG PGP G+ G P   GV G  G PG+ G +GE G PG  G  G Q
Sbjct: 654  GEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQ 713

Query: 328  GLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGEL 387
            GL G  G+PG  G  G KG++G  G PG     G PG QG PGE G  G  G  G RG++
Sbjct: 714  GLQGPRGLPGTPGTDGPKGASGPAGPPGA---QGPPGLQGMPGERGAAGIAGPKGDRGDV 770

Query: 388  GPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGER 447
            G  G  G PGK    G  GL G  GPPG  G  G++G VG PGP G  GA G  GE GE 
Sbjct: 771  GEKGPEGAPGK---DGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGET 827

Query: 448  GELGDIGLPGPKGSAGNP---GEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLP 504
            G  G  G  GP G+ G P   GE G  G +G  G PG +GP G PGP+G  G  G  G  
Sbjct: 828  GPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGAR 887

Query: 505  GVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGEN 564
            G QGPPG         +V                     G  G  G PGPPGPPGP G++
Sbjct: 888  GAQGPPGATGFPGAAGRV---------------------GPPGSNGNPGPPGPPGPSGKD 926

Query: 565  GFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR----GPNGLP---GAIGLP 617
            G  G  G  G PG  G PG  G  GP G+ GE G+ GP G     GP GL    G +GLP
Sbjct: 927  GPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLP 986

Query: 618  GDPG----PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
            G  G    P   G +G  G++G PG +G  G PGP GPPGL G
Sbjct: 987  GQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTG 1029



 Score =  512 bits (1318), Expect = e-145
 Identities = 303/709 (42%), Positives = 352/709 (49%), Gaps = 74/709 (10%)

Query: 18  LCLCAAQRGPPGEQ----------GPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEP 67
           L   + Q GP G++          GP GPPGP G  G  G  GDRG KG  G PGP G  
Sbjct: 93  LATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRD 152

Query: 68  GKPGAPGKPGTPGADGLTGPDGSPGSIGSK---------------GQKGEPGVPGSRGFP 112
           G+PG PG PG PG  G  GP G  G+  ++                 +G  G  G RG P
Sbjct: 153 GEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPP 212

Query: 113 GRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIG----FHDGDPLC 168
           G    G PGP G  G PGE G  G  G  G RGPPGPPG PG  G  G      +  P  
Sbjct: 213 GPA--GAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPG 270

Query: 169 PNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLR 228
           P     G  G PGLPG++GH+G  G  G  G  G  G +G+ G  GE G+ GP G +GL 
Sbjct: 271 PQGA-RGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLP 329

Query: 229 GITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLP 288
           G  G  G  G  GARG DG+PGP G PG  G  G  G PG  G KG+ G  GARG  G  
Sbjct: 330 GERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQ 389

Query: 289 GPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGST 348
           GP+G+ G PG  G  G  G PGT G PG  G  G  G+ G PG PG  G  G  G  G  
Sbjct: 390 GPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPL 449

Query: 349 GAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLP 408
           G  G+ G+ G +G  G+QGP GE GP GPQG PG  GE G  G+ G PG +G +G PG  
Sbjct: 450 GPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGER 509

Query: 409 GLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEP 468
           G PG  G PG  G  G  G PG +G  G +G +G  G+ G  G+ GLPG +G  G PG+ 
Sbjct: 510 GAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDA 569

Query: 469 GLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLP---GVQGPPGRAPTDQHIKQVCMR 525
           G +G  G  G PG +G  GPPGP+G +G+ G  G P   G  G PG+A            
Sbjct: 570 GPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKA------------ 617

Query: 526 VIQEHFAEMAASLK--RPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPP- 582
              E     A  L+      G TG  G PGP GP G  GE G PG  G +GLPG  GPP 
Sbjct: 618 --GEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPG 675

Query: 583 --------------GALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRN 628
                         GA GL GP+G+ G  GERG P  G  GL G  GLPG PG  + G  
Sbjct: 676 EGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSP--GAQGLQGPRGLPGTPG--TDGPK 731

Query: 629 GRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPD 677
           G  G  GPPG  G PG+ G PG  G  G   P       G+    KGP+
Sbjct: 732 GASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGE----KGPE 776



 Score =  499 bits (1285), Expect = e-141
 Identities = 312/726 (42%), Positives = 357/726 (49%), Gaps = 82/726 (11%)

Query: 22  AAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPG---------- 71
           A ++GP G++G  G  G PG  G DG  G  G  GPPGPPGP G PG  G          
Sbjct: 128 AGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGF 187

Query: 72  -----------APGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGP 119
                        G  G  G  G  GP G+PG  G +G  GEPG PG  G  G RG PGP
Sbjct: 188 DEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGP 247

Query: 120 PGPP---GTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGF-----HDGDPLCP-- 169
           PG P   G AG PG+ G  GP G  G RG PG PG PG +G  G+       G+   P  
Sbjct: 248 PGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGV 307

Query: 170 --NACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGL 227
              +  PG +G PG  G RG  G +G  G  G  G +G +G  G  G  G  GP G  G 
Sbjct: 308 KGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGF 367

Query: 228 RGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGL 287
            G  G  G+ G  GARG +G  GP+G PG PG  G  G  G  G  G  GA+G+ G PG+
Sbjct: 368 PGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGI 427

Query: 288 ------------PGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGI 335
                       PGP+G TG  G  G+ G PG+ G KGE G  G PG AG QG PG  G 
Sbjct: 428 AGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGE 487

Query: 336 PGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGL 395
            G +G  GE G  G  G PG+    G PG +G PG+ G  GP+G PG RG  G  G  G 
Sbjct: 488 EGKRGARGEPGGVGPIGPPGE---RGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGA 544

Query: 396 PGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGL 455
            G  G  G PGLPG  G  G PG  G +G VG  G  GE G  G  G  G RG+ G +G 
Sbjct: 545 NGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGF 604

Query: 456 PGPKGSAGNP---GEPGLRGPEGSRGLPGVE------GPRGPPGPRGVQGEQGA------ 500
           PGPKG+ G P   GE GL G  G RGLPG +      GP GP GP G +GEQGA      
Sbjct: 605 PGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGF 664

Query: 501 TGLPGVQGPPGRA--PTDQHIK-------QVCMRVIQEHFAEMAASLKRPDSGATGLPGR 551
            GLPG  GPPG    P DQ +         V  R  +    E  +   +   G  GLPG 
Sbjct: 665 QGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGT 724

Query: 552 PGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR-GPNGL 610
           PG  GP G  G  G PG  G  GL G+ G  GA G+ GPKGD G+ GE+GP G  G +G 
Sbjct: 725 PGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGG 784

Query: 611 PGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPP------GPPGLPGFCEPASCT 664
            G  G  G PGPA  G NG  GE GPPG AG  G  G P      GPPG  GF  P    
Sbjct: 785 RGLTGPIGPPGPA--GANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGAD 842

Query: 665 MQAGQR 670
            Q G +
Sbjct: 843 GQPGAK 848



 Score =  445 bits (1145), Expect = e-125
 Identities = 262/592 (44%), Positives = 294/592 (49%), Gaps = 78/592 (13%)

Query: 17   GLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKP 76
            GL     +RG PGE+G PG  G  G  G+ G  G  GPKG  GP GP G  G PG  G P
Sbjct: 693  GLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMP 752

Query: 77   GTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVG 136
            G  GA G+ GP G  G +G KG +G PG  G RG  G    GPPGP G  G  GE+G  G
Sbjct: 753  GERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGP--IGPPGPAGANGEKGEVGPPG 810

Query: 137  PVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIG 196
            P G  G RG PG  G  GP G  GF         A PPG  G PG  G +G  G KG+ G
Sbjct: 811  PAGSAGARGAPGERGETGPPGPAGF---------AGPPGADGQPGAKGEQGEAGQKGDAG 861

Query: 197  EPGRQGHKGEEGDQGELGEV------GAQGPPGAQGLRGITGIV---------------G 235
             PG QG  G  G QG  G        GAQGPPGA G  G  G V               G
Sbjct: 862  APGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG 921

Query: 236  DKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIP---GLPGPKG 292
              G+ G +G  G+ GP G  G PG QG  GPPGE G  GD G  GA G P   GL G +G
Sbjct: 922  PSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRG 981

Query: 293  DTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPG 352
              GLPG  G  G PG+PG  GEPGK G PG +G +G PG  G PG  G AGE      PG
Sbjct: 982  IVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGE------PG 1035

Query: 353  KPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPG 412
            + G  G  G PG+ G  G  G RG  G  G+ G  GP GSPG  G  G  G  G  G  G
Sbjct: 1036 REGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQG 1095

Query: 413  PPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRG 472
            P G  G  G RG+ G  GP+G++G +GE GE G +G  G  GL       G PG PG  G
Sbjct: 1096 PMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGL------QGLPGPPGPSG 1149

Query: 473  PEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFA 532
             +G+ G  G  GPRGPPGP G  G+ GA G+PG  GPPG                     
Sbjct: 1150 DQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRG------------------ 1191

Query: 533  EMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPG--QMGIRGL-PGIKGP 581
                  +  ++G  G PG PGPPGPPGPPG    PG       GL P  KGP
Sbjct: 1192 ------RSGETGPAGPPGNPGPPGPPGPPG----PGIDMSAFAGLGPREKGP 1233



 Score =  389 bits (998), Expect = e-108
 Identities = 236/546 (43%), Positives = 271/546 (49%), Gaps = 48/546 (8%)

Query: 168 CPNACPPGRSGYPGLPGMRGHKGAKGEI-------GEPGRQGHKGEEGDQGELGEVGAQG 220
           CP  CP   +   G PG +G KG  G+I       G PG QG  GE+G +G+ G+ G +G
Sbjct: 86  CP-ICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKG 144

Query: 221 PPGAQGLRGITGIVGDKGEKGARGLDGEPGPQG---------------------LPGAPG 259
            PG +G  G  G  G+ G  G  G  G PG  G                     + G  G
Sbjct: 145 APGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMG 204

Query: 260 DQGQRGPPGEAGPKGDRGAEGARGIPGLP------GPKGDTGLPGVDGRDGIPGMPGTKG 313
             G RGPPG AG  G +G +G  G PG P      GP+G  G PG  G DG  G PG  G
Sbjct: 205 PMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAG 264

Query: 314 EPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVG 373
           E G PGP G  G  G PG+PG+ G +G  G  G+ G  G PG  G SG PG+ G P   G
Sbjct: 265 ERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSP---G 321

Query: 374 PRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKG 433
           P GP+GLPG RG  GP G+ G  G  G  G  G PG  GP G PG  G  G  GE GP  
Sbjct: 322 PMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGP-- 379

Query: 434 EQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRG 493
             GA G EG  G RGE G  G PGP G++GNPG  G+ G +GS G PG+ G  G PGPRG
Sbjct: 380 -TGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRG 438

Query: 494 VQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPG 553
             G QGATG  G +G  G         +   +          A     + G  G  G PG
Sbjct: 439 PPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPG 498

Query: 554 PPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR-GPNGLPG 612
             GP GPPGE G PG  G  G  G+ GP GA G RGP G  G KG  G PGR G  GLPG
Sbjct: 499 GVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG 558

Query: 613 AIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPP---GPPGLPGFCEPASCTMQAGQ 669
           A GL G PG A  G  G+ G  G PG  G PG PGP    G PG+ GF  P     + G 
Sbjct: 559 ARGLTGRPGDA--GPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPG- 615

Query: 670 RAFNKG 675
           +A  KG
Sbjct: 616 KAGEKG 621



 Score =  288 bits (736), Expect = 1e-77
 Identities = 186/457 (40%), Positives = 204/457 (44%), Gaps = 85/457 (18%)

Query: 266 PPGEAGPKGDRGAEGARGIPGLPGP----------------------------------K 291
           P GE  P        A G PG  G                                   K
Sbjct: 81  PFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDK 140

Query: 292 GDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQG------------------LPGVP 333
           G+ G PG  GRDG PG PG  G PG PGPPG  GL G                  L  + 
Sbjct: 141 GEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQ 200

Query: 334 GIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSP 393
           G  G  G  G  G  GAPG  G  GN G+PG+ G  G +GPRGP G PG  G+ G  G P
Sbjct: 201 GPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKP 260

Query: 394 GLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDI 453
           G  G+ G  G  G  G PG PGLPG+KG RG  G  G KGE GA G +GE+G  GE G  
Sbjct: 261 GKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSP 320

Query: 454 GLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRA 513
           G  GP+G  G  G  G  G  G+RG  G  GP GPPGP G  G  G  G PG +G  G  
Sbjct: 321 GPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAG-- 378

Query: 514 PTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIR 573
           PT                A      + P  G  G PG PGP G  G PG +G PG  G  
Sbjct: 379 PTG---------------ARGPEGAQGP-RGEPGTPGSPGPAGASGNPGTDGIPGAKGSA 422

Query: 574 GLPGIKGPPGALGLRGP------KGDLGEKGERGPPG-------RGPNGLPGAIGLPGDP 620
           G PGI G PG  G RGP       G LG KG+ G PG       +GP G PG  G  G P
Sbjct: 423 GAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAP 482

Query: 621 GPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGF 657
           GPA  G  G+ G RG PG  G  G PG  G PG  GF
Sbjct: 483 GPA--GEEGKRGARGEPGGVGPIGPPGERGAPGNRGF 517



 Score =  209 bits (531), Expect = 9e-54
 Identities = 126/299 (42%), Positives = 142/299 (47%), Gaps = 59/299 (19%)

Query: 5    ARDRGALGLLLLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPG-- 62
            A  RG +GL          QRG  G  G PGP G PG  G  G  GDRGP GP GPPG  
Sbjct: 977  AGQRGIVGL--------PGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLT 1028

Query: 63   -PAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPG 121
             PAGEPG+ G+PG  G PG DG  G  G  G  G+ G  G PG PGS        PGP G
Sbjct: 1029 GPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGS--------PGPAG 1080

Query: 122  PPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPG 181
            P G  G  GE G  GP+G  G  G  G  GP GPRG                 G +G PG
Sbjct: 1081 PTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRG---------------DKGEAGEPG 1125

Query: 182  LPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKG 241
              G++GH+G  G  G PG  G  G++G  G  G  G +GPPG          VG  G+ G
Sbjct: 1126 ERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGP---------VGPSGKDG 1176

Query: 242  ARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVD 300
            A G+ G  GP G  G  G+ G  GPPG  GP            PG PGP G    PG+D
Sbjct: 1177 ANGIPGPIGPPGPRGRSGETGPAGPPGNPGP------------PGPPGPPG----PGID 1219



 Score =  201 bits (511), Expect = 2e-51
 Identities = 138/404 (34%), Positives = 159/404 (39%), Gaps = 129/404 (31%)

Query: 368 PPGEVGPRGPQGLPGSRGELGPVGSPGLPGKL---------------------------- 399
           P GE  P  P  L  + G+ GP G  G PG +                            
Sbjct: 81  PFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDK 140

Query: 400 ---------------GSLGSPGLPGLPGPPGLPG------------------------MK 420
                          G+ G+PG PG PGPPG PG                        M+
Sbjct: 141 GEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQ 200

Query: 421 GDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLP 480
           G  G +G  GP G  GA G +G  G  GE G+ G+ GP G  G PG PG  G +G  G P
Sbjct: 201 GPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKP 260

Query: 481 GVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKR 540
           G  G RGPPGP+G +G  G  GLPGV+G  G    D                        
Sbjct: 261 GKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLD------------------------ 296

Query: 541 PDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGER 600
              GA G  G PG  G  G PGENG PG MG RGLPG +G  G  G  G +G+ G+ G  
Sbjct: 297 ---GAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPA 353

Query: 601 GPPG-------------------------RGPNGLPGAIGLPGDPG----------PASY 625
           GPPG                         RGP G  G  G PG PG          P + 
Sbjct: 354 GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTD 413

Query: 626 GRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQ 669
           G  G  G  G PG+AG PG PGP GPPG  G   P     Q G+
Sbjct: 414 GIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGE 457


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score =  538 bits (1386), Expect = e-153
 Identities = 318/707 (44%), Positives = 369/707 (52%), Gaps = 74/707 (10%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGP------PGPPGPAGEPGKPGAPGKPGT- 78
            G PG  GPPG  G PG+ G  G DG+RG KG       PGP GP G+PG PG PG PG  
Sbjct: 925  GAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKG 984

Query: 79   -PGADGLTGPDGSPGSIGSK-----------------------GQKGEPGVPGSRGFPGR 114
              G  GL G  G PG +G+K                       G  G PG PGSRG PG 
Sbjct: 985  KDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI 1044

Query: 115  GIPGPPGP---------PGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGF-HDG 164
            G+ GPPGP         PG+ GLPG  G  GP G  G  G PG  GPPG  G       G
Sbjct: 1045 GVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPG 1104

Query: 165  D------PLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGR---QGHKGEEGDQGELGE 215
            D       +C N CPPG    PGLPG+ G KG KG  G+PGR   +G KGE G  G  G 
Sbjct: 1105 DINLLAKDVC-NDCPPGP---PGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGP 1160

Query: 216  VGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQ---GQRGPPGEAGP 272
             G  GP G+QG RG  G VG KG++G  G+ G  GP G PG PG     G  GPPG  G 
Sbjct: 1161 PGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGS 1220

Query: 273  KGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGV 332
             G  G  G +G  GLPG  G+ G  G DG+ G PG PG  GEPG PGP G  G  G  G 
Sbjct: 1221 PGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGH 1280

Query: 333  PGIPGAKGVAGEKGSTGAPGK---PGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGP 389
             G  GA G  GE G+ G PG+   PG+ G++G  G QGP G  GP G  G PGS GE GP
Sbjct: 1281 TGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGP 1340

Query: 390  VGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGE 449
             G+PG  G  G  GSPGLPG  GP G PG  G++GV G+ G  G+ G  G +GE G+ G 
Sbjct: 1341 SGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGI 1400

Query: 450  LGDIGLPGPKGSAGNPGEPGLRGPE---GSRGLPGVEGPRGPPGPRGVQGEQGATGLPGV 506
             GD G PG KG  G+PG PG +G     G +GLPG  GP GPPGP          G PG 
Sbjct: 1401 KGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGP---------PGQPGF 1451

Query: 507  QGPPGRAPTDQHIKQVCMRVIQEHFAEMAASL--KRPDSGATGLPGRPGPPGPPGPPGEN 564
             G  G +P+ + ++++    + +      A L  + P +      GRPGPPGPPG  G  
Sbjct: 1452 PGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLP 1511

Query: 565  GFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPAS 624
            G  G MG  G PG  G  G  G  GPKG+ G KG+ G PG G  G  G  G+PG PG   
Sbjct: 1512 GRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPG 1571

Query: 625  YGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRA 671
            Y ++G  G  GP G  G  G PG PGPPG PG C+P+ C   A   A
Sbjct: 1572 YAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPSQCAYFASLAA 1618



 Score =  521 bits (1342), Expect = e-148
 Identities = 311/724 (42%), Positives = 359/724 (49%), Gaps = 94/724 (12%)

Query: 24   QRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADG 83
            Q G  GEQG PGP G  G PG  G  G  GP+G  GPPG  G  GK G  G PG PG  G
Sbjct: 652  QEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLG 711

Query: 84   LTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR-GIPGPPGPPGTAGLPGELGRVGPVGDPG 142
            L GP G PG  G  G  G PG+PG  GFPG+ G PGP GPPG  G  G  G  G  G+PG
Sbjct: 712  LQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPG 771

Query: 143  RRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQG 202
             RG  G PG PG RG IG      L       G +G PG PG  G +G KG+ GE G  G
Sbjct: 772  ERGEDGLPGKPGLRGEIG---EQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELG 828

Query: 203  HKGEEGDQGELGEVGAQGPPGAQGLRGI-------TGIVGDKGEKGARGLDGEPGPQGLP 255
              G +GD+GE GE G  GPPG  G   +        G  G KGEKG  GL GEPG QG P
Sbjct: 829  LPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRP 888

Query: 256  GAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLP---------GPKGDTGLPGV------- 299
            G  G QG  GPPG  G +G  GA GA G PG P         GP G  G PG+       
Sbjct: 889  GELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKD 948

Query: 300  --------DGRDGIPGMPGTKGEPGKPGPP--------GDAGLQGLPGVPGIPGAKG--- 340
                     G +G PG  G +G+PG PG P        G+ GL+G PG+PG  G K    
Sbjct: 949  GERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACG 1008

Query: 341  --------------VAGEKGSTGAPGKPGQMGN-----SGKPGQQGPPGEVGPRGPQGLP 381
                          V G++G+ G PG PG  G+     +G PG  GPPG+ G  G +GLP
Sbjct: 1009 KVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLP 1068

Query: 382  GSRGELGPVGSPGLPGKLGSLGSPGLPGL---------------------PGPPGLPGMK 420
            G  G  GP G  G PG  G  G PG PGL                     PGPPGLPG+ 
Sbjct: 1069 GFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLP 1128

Query: 421  GDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGN---PGEPGLRGPEGSR 477
            G +G  G PG  G +G  G++GEAG  G  G  G+ GP+GS G     GE G +G +G  
Sbjct: 1129 GFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHP 1188

Query: 478  GLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAAS 537
            G+PG  GP G PGP G  G  GA G PG+QG PG+           +  I     +    
Sbjct: 1189 GVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRD 1248

Query: 538  LKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEK 597
             K    G  G  G PG PGP G  G  GF G  G  G PG +G  GA+GL G +G  G+ 
Sbjct: 1249 GKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKD 1308

Query: 598  GERGPPG----RGPNGLPGAIGLPGDPG-PASYGRNGRDGERGPPGVAGIPGVPGPPGPP 652
            G+ GP G    +GP G PG  G PG PG P   G  G+ G +G  G  G+PG  GP GPP
Sbjct: 1309 GDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPP 1368

Query: 653  GLPG 656
            G PG
Sbjct: 1369 GEPG 1372



 Score =  521 bits (1342), Expect = e-148
 Identities = 328/793 (41%), Positives = 372/793 (46%), Gaps = 177/793 (22%)

Query: 25   RGPPGEQGPPGPPG------------PPGVPGIDGIDGDRGPKGPPGPPGPAGEPG---- 68
            RGP G +G  GPPG            PPG+PG+ G+ G  GP G PGPPGP G PG    
Sbjct: 677  RGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGE 736

Query: 69   -----KPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----RGIPGP 119
                 KPG PG  G PG DG  GP G PG+ G  G++GE G+PG  G  G    +G+ G 
Sbjct: 737  IGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGR 796

Query: 120  PGPPGTAGLP------------------GELGRVGPVGDPGRRGPPGPPGPPGPRGTIGF 161
            PG  G AGLP                  GELG  G  GD G +G  GP GPPG  GT   
Sbjct: 797  PGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSL 856

Query: 162  HDGDPLCP-NACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQG 220
                P  P    P G  G PGLPG  G +G  GE+G  G  G  G +G +G  G  GA G
Sbjct: 857  FTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAG 916

Query: 221  PP------------------GAQGLRGITGIVGDKGEKGARGLDGEPGP---------QG 253
             P                  GA GLRG  G  G++GEKGA G +G PGP          G
Sbjct: 917  NPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPG 976

Query: 254  LPGAP-----GDQGQRGPPGEAGPKGD--------------------RGAEGARGIPGLP 288
            LPG P     G+ G RG PG  GP G                     +G  GA GIPG P
Sbjct: 977  LPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSP 1036

Query: 289  GPKGDTGL-----PGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPG------------ 331
            G +GD G+     PG  G  G  G PG++G PG PGP G AG  G PG            
Sbjct: 1037 GSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPG 1096

Query: 332  ---------------------VPGIPGAKGVAGEKGSTGAPGKPGQMGNSGK------PG 364
                                  PG PG  G+ G KG  G PGKPG+ G  GK      PG
Sbjct: 1097 LSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPG 1156

Query: 365  QQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRG 424
              GPPG  GP+G QG  G+ GE+G  G  G PG  G +G PG PG PG  G+ G  G  G
Sbjct: 1157 LPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPG 1216

Query: 425  VVGEP---GPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPG 481
            + G P   GP G QG SG  G  GE G+ G  G PGP G  G  GEPGL GPEG+RG PG
Sbjct: 1217 IQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPG 1276

Query: 482  VEGPRGPPGPRGVQGEQGATGLPGVQGPPGR----APTDQHIKQVCMRVIQEHFAEMAAS 537
             +G  G  G  G +GE GA GLPG +G PG+     PT     Q                
Sbjct: 1277 FKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQG--------------- 1321

Query: 538  LKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGP------------PGAL 585
              R   G  G PG PG PGP G PG+ G  G+ G  GLPG  GP            PG  
Sbjct: 1322 -PRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKE 1380

Query: 586  GLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPG-PASYGRNGRDGERGPPGVAGIP 643
            G+ G  G+ G KGERG PG +G  G PG  G PGDPG P   G  G  G +G PG  G  
Sbjct: 1381 GVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPV 1440

Query: 644  GVPGPPGPPGLPG 656
            G PGPPG PG PG
Sbjct: 1441 GPPGPPGQPGFPG 1453



 Score =  504 bits (1299), Expect = e-143
 Identities = 315/752 (41%), Positives = 361/752 (48%), Gaps = 125/752 (16%)

Query: 11   LGLLLLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGP------- 63
            +G L    C C     P GE+G  G  GP G+PG  G  G  GP G PGP G        
Sbjct: 468  IGFLKTINCSC-----PAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKGDVGIG 522

Query: 64   ---AGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPP 120
                GE G+ G+ G PG PG DG  G  G PG +G  G  GE G+ G +G P  G+PGPP
Sbjct: 523  PFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPP--GLPGPP 580

Query: 121  GPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYP 180
            G  G  GL GE G  G  G+ G RG  G PG PG  G  G             PG SG  
Sbjct: 581  GRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQG------------RPGPSGVA 628

Query: 181  GLPGMRGHKGAKGEIGEPG----RQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGD 236
            G  G +G  G  G  G PG    ++G KGE+G  G  G  GA GPPGA+G  G  G  G 
Sbjct: 629  GPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGP 688

Query: 237  KGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGAR---GIPGLPGPKGD 293
             G +G RG  G+ GP G+PG  G QG  GPPG  GP G  G+ G     G PG PGP G 
Sbjct: 689  PGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGP 748

Query: 294  TGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGK 353
            TG PG DG +G PG PGTKGEPG+ G  G  G  GL G  G  G  G  GEKG  G PG 
Sbjct: 749  TGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGA 808

Query: 354  PGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKL-------------- 399
            PG  G  G+ G QG  GE+G  G +G  G +GE GP G PGLPG                
Sbjct: 809  PGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQG 868

Query: 400  --GSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPG 457
              G  G PGLPG PG  G PG  G +G  G PG KG++GA G  G AG  G  G +G PG
Sbjct: 869  PKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPG 928

Query: 458  PKGSAGNPGEPGLR---GPEGSRGLPGVEGPRGPPGPRGVQGEQGATGL----------- 503
            P G  G+ G PGLR   G +G RG  G  G  G PGP G +G+ GA GL           
Sbjct: 929  PSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGE 988

Query: 504  PGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRP----------- 552
            PG++G PG  P     K  C +V       +     + D GA G+PG P           
Sbjct: 989  PGLRGSPG-LPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVA 1047

Query: 553  GPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-------- 604
            GPPGP GPPG+ G PG    RGLPG  GP G  G  G  G+ GE+G  G PG        
Sbjct: 1048 GPPGPSGPPGDKGSPGS---RGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPG 1104

Query: 605  --------------RGPNGLPGAIGLPGDPG----PASYGRNGRDGERGPPGVAGIPGVP 646
                           GP GLPG  G  GD G    P   G  G+ GE GPPG+ G PG+ 
Sbjct: 1105 DINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIA 1164

Query: 647  GPPGP------------------PGLPGFCEP 660
            GP G                   PG+PGF  P
Sbjct: 1165 GPQGSQGERGADGEVGQKGDQGHPGVPGFMGP 1196



 Score =  498 bits (1283), Expect = e-141
 Identities = 305/711 (42%), Positives = 358/711 (50%), Gaps = 75/711 (10%)

Query: 16   LGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGK 75
            LGL     + G  G +G PG  G PG+PG  G+ G +GP G PGPPG  G PG  G  G+
Sbjct: 535  LGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGE 594

Query: 76   PGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGT--------- 125
             GT G  G  G DG PG  G  GQ+G PG  G  G  G +G  GP GPPG          
Sbjct: 595  KGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEG 654

Query: 126  ----AGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHD-----GDPLCPNAC---- 172
                 G PG  G  G  G PG RGP GP G  GP G  G        G P  P       
Sbjct: 655  LKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQG 714

Query: 173  PPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITG 232
            PPG  G PG PG  G  G  GEIG PG+ G  G  G  G+ G  G  GPPG +G  G  G
Sbjct: 715  PPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERG 774

Query: 233  IVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKG 292
              G  G+ G RG  GE G  G PG  G+ G  G PG  G +G++G +G +G  GLPG KG
Sbjct: 775  EDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKG 834

Query: 293  DTGLPGVDGRDGIPGMPGT----------------KGEPGKPGPPGDAGLQGLP------ 330
            D G  G  G  G PG+PGT                KGE G PG PG+ GLQG P      
Sbjct: 835  DRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQ 894

Query: 331  GVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLP---GSRGEL 387
            G  G PGAKG  G  G+ GA G PG  G+ G PG  GPPG VG  G +G P   G RGE 
Sbjct: 895  GPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEK 954

Query: 388  GPVGSPGLPGKLGSLGSPGLPGLPGPP--GLPGMKGDRGVVGEPGPKGEQGASGEE---- 441
            G  G  G PG +G  G PG PGLPGPP  G  G  G RG  G PGP G + A G+     
Sbjct: 955  GAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSE 1014

Query: 442  ----GEAGERGELGDIGLPGPKGSAGNP-----GEPGLRGPEGSRGLPGVEGPRGPPGPR 492
                G    +G+ G  G+PG  GS G+P     G PG  GP G +G PG  G  G PGP+
Sbjct: 1015 NCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQ 1074

Query: 493  GVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRP 552
            G  G  GA G PG +GPPG+      +    + ++ +   ++         G  GLPG  
Sbjct: 1075 GPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAK---DVCNDCPPGPPGLPGLPGFK 1131

Query: 553  GPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLP 611
            G  G PG PG  G  G+ G  G PG+ GPPG  G +G +G+ G  GE G  G +G  G+P
Sbjct: 1132 GDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVP 1191

Query: 612  GAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGP------PGLPG 656
            G +G PG+PGP   G +G  G  GPPG+ G PG  GPPGP      PG+PG
Sbjct: 1192 GFMGPPGNPGPP--GADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPG 1240



 Score =  442 bits (1137), Expect = e-124
 Identities = 277/663 (41%), Positives = 327/663 (49%), Gaps = 110/663 (16%)

Query: 60   PPGPAG-----EPGKPGAPGKPGTPGADGLTGPDGSPGSIGSK---GQKGEPGVPGSRGF 111
            P GP       EP  P  P +P TPG++ +    G   +I      G+KGE GV G  G 
Sbjct: 439  PSGPCQVTVVTEPPPPPPPQRPPTPGSEQI----GFLKTINCSCPAGEKGEMGVAGPMGL 494

Query: 112  PGR----GIPGPPGPPGTAGLPGELGRVGPVG--DPGRRGPPGPPGPPGPRGTIGFHDGD 165
            PG     G  GP G PG  G  G++G +GP G  + G +G  G PGPPG  G+ G     
Sbjct: 495  PGPKGDIGAIGPVGAPGPKGEKGDVG-IGPFGQGEKGEKGSLGLPGPPGRDGSKGMRG-- 551

Query: 166  PLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQ 225
                    PG  G PGLPG  G +G +G  G PG  G  G  G QGE GE G +G  G +
Sbjct: 552  -------EPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGER 604

Query: 226  GLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPG----EAGPKGDRGAEGA 281
            GL G  G  GD G++G  G  G  GPQG  G  G  G  G PG    + G KG++GA G 
Sbjct: 605  GLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGP 664

Query: 282  RGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGV 341
            RG  G PGP G  G  G +GRDG PG+ G +G+ G  GPPG  GL GL G PG PG  G 
Sbjct: 665  RGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGP 724

Query: 342  AGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGK--- 398
             G  GS G PG+ G  G  G PG  GPPG+ GP GP G PG++GE G  G  GLPGK   
Sbjct: 725  PGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGL 784

Query: 399  LGSLGSPGLPGLPGP------PGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGD 452
             G +G  GL G PG       PG PG  G RG  G+ G KGE G  G +G+ GE+GE G 
Sbjct: 785  RGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGP 844

Query: 453  IG----------------LPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQG 496
             G                +PG +G  G  G+PGL G  G +G PG  GP+GP GP G +G
Sbjct: 845  AGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKG 904

Query: 497  EQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPG 556
            ++GA G PG  G PG AP                             G  G PG  GPPG
Sbjct: 905  QEGAHGAPGAAGNPG-AP-----------------------------GHVGAPGPSGPPG 934

Query: 557  PPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGL 616
              G PG  G PG+ G RG  G  G  G+ G  GP+GD G  G  GPPG+G +G PG  G 
Sbjct: 935  SVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGS 994

Query: 617  PGDPGP---------------ASYGRNGRDGERGPPGVAGIP--------GVPGPPGPPG 653
            PG PGP                + G     G+RG PG+ G P        GV GPPGP G
Sbjct: 995  PGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSG 1054

Query: 654  LPG 656
             PG
Sbjct: 1055 PPG 1057



 Score =  294 bits (752), Expect = 2e-79
 Identities = 175/430 (40%), Positives = 208/430 (48%), Gaps = 83/430 (19%)

Query: 25   RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGL 84
            +G PG++GPPGP GP G+PGI G +G  G  G PGPPG  G+ G+PG PG  G  G  G 
Sbjct: 1218 QGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGF 1277

Query: 85   TGPDGSPGSIGSKGQKGEPGVPGSRGFPGR-GIPGPPGPPGTAGLPGELGRVGPVGDPGR 143
             G  G  G+ G +G+ G  G+PG  G PG+ G  GP GP G           GP G PG+
Sbjct: 1278 KGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQ---------GPRGPPGK 1328

Query: 144  RGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGH 203
             G PG PG PGP GT G              G  G  G PG+ G  G +G  GEPG +G 
Sbjct: 1329 NGSPGSPGEPGPSGTPG------------QKGSKGENGSPGLPGFLGPRGPPGEPGEKGV 1376

Query: 204  KGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQ 263
             G+EG  G+ GE      PG +G RG  GI GDKG  G +G  G+PG  G  G  G  G 
Sbjct: 1377 PGKEGVPGKPGE------PGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGP 1430

Query: 264  RGPPGEAGPKGDRGAEGARGIPGLPG---------------------------------- 289
            +G PGE GP G  G  G  G PGL G                                  
Sbjct: 1431 QGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPA 1490

Query: 290  ----PKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEK 345
                 +G  G PG  G+DG+PG  G  GEPG+   PG  GL+G  G  G  G +G  G+ 
Sbjct: 1491 YMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGR---PGQGGLEGPSGPIGPKGERGAKGDP 1547

Query: 346  GSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSP 405
            G+ G  G  G+MG  G PGQ G PG     G  G+PG +GE GP G PGLPG        
Sbjct: 1548 GAPGV-GLRGEMGPPGIPGQPGEPG-YAKDGLPGIPGPQGETGPAGHPGLPGP------- 1598

Query: 406  GLPGLPGPPG 415
                 PGPPG
Sbjct: 1599 -----PGPPG 1603



 Score =  291 bits (746), Expect = 1e-78
 Identities = 191/465 (41%), Positives = 221/465 (47%), Gaps = 58/465 (12%)

Query: 249 PGPQGLPGAPGDQ--GQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIP 306
           P P   P  PG +  G       + P G++G  G  G  GLPGPKGD G     G  G P
Sbjct: 454 PPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIG---AIGPVGAP 510

Query: 307 GMPGTKGEPG----KPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGN--- 359
           G  G KG+ G      G  G+ G  GLPG PG  G+KG+ GE G  G PG PG++G    
Sbjct: 511 GPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGP 570

Query: 360 SGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGM 419
            G PG  GPPG VG  G QG  G +G  G  G  GL G  G  G  G  G PGP G+ G 
Sbjct: 571 QGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGP 630

Query: 420 KGDRGVVGEPGPKGEQGA----SGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEG 475
           +G++G VG  GP G  G+     G +GE G  G  G  G PGP G+ G  G  G  GP G
Sbjct: 631 QGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPG 690

Query: 476 SRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMA 535
            +GL G +G  GPPG  G+ G QG  G PGV GPPG   +                 E+ 
Sbjct: 691 LQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLP------------GEIG 738

Query: 536 ASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPG------------------ 577
              K    G TG PG+ GP GPPGPPG  G PG+ G  GLPG                  
Sbjct: 739 FPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPG 798

Query: 578 ------IKGPPGALGLRGPKGDLGEKGERGPPG----RGPNGLPGAIGLPGDPGPASY-- 625
                 + G PG  G+RG KGD GEKGE G PG    RG  G  G  G PG PG  S   
Sbjct: 799 EKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFT 858

Query: 626 GRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQR 670
                 GE+GP G  G PG+PG PG  G PG   P   T   G +
Sbjct: 859 PHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAK 903



 Score =  199 bits (507), Expect = 5e-51
 Identities = 124/318 (38%), Positives = 152/318 (47%), Gaps = 59/318 (18%)

Query: 367 GPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGL----PGMKGD 422
           G  GE+G  GP GLPG +G++G +         G +G+PG  G  G  G+     G KG+
Sbjct: 481 GEKGEMGVAGPMGLPGPKGDIGAI---------GPVGAPGPKGEKGDVGIGPFGQGEKGE 531

Query: 423 RGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGV 482
           +G +G PGP G  G+ G  GE GE   LG+ GLPG  G  G  G PGL GP G  G PG+
Sbjct: 532 KGSLGLPGPPGRDGSKGMRGEPGE---LGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGL 588

Query: 483 EGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPD 542
           +G RG  G RG +GE+G  G PG  G                                  
Sbjct: 589 QGERGEKGTRGEKGERGLDGFPGKPGD--------------------------------- 615

Query: 543 SGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPG-IKGPPGALGLRGPKGDLGEKGERG 601
              TG  GRPGP G  GP GE G  G  G  G+PG +    G  G +G  G  G +G  G
Sbjct: 616 ---TGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPG 672

Query: 602 PPG-RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEP 660
           PPG RGP G  G  G PG       G  G+ G+ GPPG+ G+ G+ GPPGPPG+PG   P
Sbjct: 673 PPGARGPIGPEGRDGPPG-----LQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGP 727

Query: 661 ASCTMQAGQRAFNKGPDP 678
                  G+  F   P P
Sbjct: 728 GGSPGLPGEIGFPGKPGP 745



 Score =  112 bits (280), Expect = 1e-24
 Identities = 62/138 (44%), Positives = 70/138 (50%), Gaps = 10/138 (7%)

Query: 18   LCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPG 77
            L    AQ  P   +   G PGPPG PG DG+ G  GP G PG PG  G  G  G  G  G
Sbjct: 1480 LAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKG 1539

Query: 78   TPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGP 137
              GA    G  G+PG +G +G+ G PG+PG  G PG    G P      G+PG  G  GP
Sbjct: 1540 ERGA---KGDPGAPG-VGLRGEMGPPGIPGQPGEPGYAKDGLP------GIPGPQGETGP 1589

Query: 138  VGDPGRRGPPGPPGPPGP 155
             G PG  GPPGPPG   P
Sbjct: 1590 AGHPGLPGPPGPPGQCDP 1607


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score =  538 bits (1385), Expect = e-153
 Identities = 313/673 (46%), Positives = 351/673 (52%), Gaps = 80/673 (11%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 85
            GP G+ G PGPPGPPG  G  G+ G  GPKG  G PG AGE G PG PG  G  G DG  
Sbjct: 557  GPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEA 616

Query: 86   GPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRG 145
            G  G PG  G  G++GE G  GS GF  +G+PGP GPPG AG PGE G  G +G PG  G
Sbjct: 617  GAQGPPGPAGPAGERGEQGPAGSPGF--QGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSG 674

Query: 146  PPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKG 205
              G  G PG RG  G            PPG +G  G  G  G+ GAKG+ G PG  G +G
Sbjct: 675  ARGERGFPGERGVQG------------PPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQG 722

Query: 206  EEGDQGELGEVGAQGPPGAQGLRGITG---IVGDKGEKGARGLDGEPGPQGLPGAPGDQG 262
              G QG  GE GA G PG +G RG  G     G  G+ G RGL G  GP G  GAPGD+G
Sbjct: 723  APGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKG 782

Query: 263  QRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPG 322
            + GP G AGP G RGA G RG PG PGP G  G PG DG+ G  G PG  G  G  GPPG
Sbjct: 783  ESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPG 842

Query: 323  DAGLQGLPG------VPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRG 376
             AG  G PG       PG  GA+G AG  G+TG PG  G++G  G  G  GPPG  GP G
Sbjct: 843  PAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAG 902

Query: 377  PQGLPGSRGELGP------VGSPGLPGKLGSLGSPGL------PGLPGPPG--------- 415
             +G  G RGE GP      VG PG PG  G  GSPG       PG PGP G         
Sbjct: 903  KEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVG 962

Query: 416  LPGMKGDRGVVGEPGPKGE---QGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRG 472
            LPG +G+RG  G PGP GE   QG SG  GE G  G +G  GL GP G +G  G PG  G
Sbjct: 963  LPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEG 1022

Query: 473  PEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFA 532
              G  G PG +G RG  GP G  G  GA G PG  GP G++                   
Sbjct: 1023 SPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKS------------------G 1064

Query: 533  EMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKG---------PPG 583
            +   +     +G  G  G  GP GP GP G+ G  G+ G RG+ G +G         PPG
Sbjct: 1065 DRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPG 1124

Query: 584  ALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASY-GRNGRDGERGPPGVAGI 642
            + G +GP G  G  G RGPPG    G PG  GL G PGP    G  GR G+ GP    G 
Sbjct: 1125 SPGEQGPSGASGPAGPRGPPGSA--GAPGKDGLNGLPGPIGPPGPRGRTGDAGP---VGP 1179

Query: 643  PGVPGPPGPPGLP 655
            PG PGPPGPPG P
Sbjct: 1180 PGPPGPPGPPGPP 1192



 Score =  535 bits (1378), Expect = e-152
 Identities = 315/688 (45%), Positives = 353/688 (51%), Gaps = 86/688 (12%)

Query: 17   GLCLCAAQRGPPGEQGP---------PGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEP 67
            GL       GP G+ GP         PGPPGPPG  G  G+ G  GPKG  G PG AGE 
Sbjct: 539  GLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGER 598

Query: 68   GKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAG 127
            G PG PG  G  G DG  G  G PG  G  G++GE G  GS GF  +G+PGP GPPG AG
Sbjct: 599  GVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGF--QGLPGPAGPPGEAG 656

Query: 128  LPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRG 187
             PGE G  G +G PG  G  G  G PG RG  G            PPG +G  G  G  G
Sbjct: 657  KPGEQGVPGDLGAPGPSGARGERGFPGERGVQG------------PPGPAGPRGANGAPG 704

Query: 188  HKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGIT---GIVGDKGEKGARG 244
            + GAKG+ G PG  G +G  G QG  GE GA G PG +G RG     G  G  G+ G RG
Sbjct: 705  NDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRG 764

Query: 245  LDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDG 304
            L G  GP G  GAPGD+G+ GP G AGP G RGA G RG PG PGP G  G PG DG+ G
Sbjct: 765  LTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPG 824

Query: 305  IPGMPGTKGEPGKPGPPGDAGLQGLP------GVPGIPGAKGVAGEKGSTGAPGKPGQMG 358
              G PG  G  G  GPPG AG  G P      G PG  GA+G AG  G+TG PG  G++G
Sbjct: 825  AKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVG 884

Query: 359  NSGKPGQQGPPGEVGPRGPQGLPGSRGELGP------VGSPGLPGKLGSLGSP------G 406
              G  G  GPPG  GP G +G  G RGE GP      VG PG PG  G  GSP      G
Sbjct: 885  PPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAG 944

Query: 407  LPGLPGPP---------GLPGMKGDRGVVGEPGPKGE---QGASGEEGEAGERGELGDIG 454
             PG PGP          GLPG +G+RG  G PGP GE   QG SG  GE G  G +G  G
Sbjct: 945  APGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPG 1004

Query: 455  LPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAP 514
            L GP G +G  G PG  G  G  G PG +G RG  GP G  G  GA G PG  GP G++ 
Sbjct: 1005 LAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKS- 1063

Query: 515  TDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRG 574
                              +   +     +G  G  G  GP GP GP G+ G  G+ G RG
Sbjct: 1064 -----------------GDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRG 1106

Query: 575  LPGIK---------GPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGP-AS 624
            + G +         GPPG+ G +GP G  G  G RGPPG    G PG  GL G PGP   
Sbjct: 1107 IKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSA--GAPGKDGLNGLPGPIGP 1164

Query: 625  YGRNGRDGERGPPGVAGIPGVPGPPGPP 652
             G  GR G+ GP G  G PG PGPPGPP
Sbjct: 1165 PGPRGRTGDAGPVGPPGPPGPPGPPGPP 1192



 Score =  534 bits (1375), Expect = e-151
 Identities = 316/700 (45%), Positives = 364/700 (52%), Gaps = 50/700 (7%)

Query: 22  AAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRG---------PKGPPGPPGPAGEPGKPGA 72
           A + G PGE+GPPGP G  G+PG  G+ G +G          KG  GP GP GEPG PG 
Sbjct: 235 AGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGE 294

Query: 73  PGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGE 131
            G PG  G  GL G  G PG+ G  G +G  G  G+ G PG  G  GPPG PG  G  GE
Sbjct: 295 NGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGE 354

Query: 132 LGRVGPVGDPGRRGPPGPPGPPGPRGTIG-----FHDGDPLCPNAC-PPGRSGYPGLPGM 185
            G  GP G  G +G  G PGPPGP G  G       DG P    A   PG +G PG PG 
Sbjct: 355 AGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGA 414

Query: 186 RGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGL 245
           RG  G +G  G PG +G+ GE G  G  G+ GA+G PG  G++G  G  G++G++GARG 
Sbjct: 415 RGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARG- 473

Query: 246 DGEPGPQGLPGAPGDQG---QRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGR 302
             EPGP GLPG PG++G    RG PG  G  G +G  G RG PG  GPKG  G  G  G 
Sbjct: 474 --EPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGE 531

Query: 303 DGIPGMPGTKGEPGKPGP------PGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQ 356
            G+PG  G  G PG PGP      PG AG  G PG PG PGA+G AG  G  G  G  G+
Sbjct: 532 AGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGE 591

Query: 357 MGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGL 416
            G +G+ G  GPPG VGP G  G  G++G  GP G  G  G+ G  GSPG  GLPGP G 
Sbjct: 592 PGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGP 651

Query: 417 PGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGS 476
           PG  G  G  G PG  G  G SG  GE G  GE G  G PGP G  G  G PG  G +G 
Sbjct: 652 PGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGD 711

Query: 477 RGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAA 536
            G PG  G +G PG +G+ GE+GA GLPG +G  G    D   K       ++    +  
Sbjct: 712 AGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRG----DAGPKGADGSPGKDGVRGLTG 767

Query: 537 SLKRP-DSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLP---GIKGPPGA---LGLRG 589
            +  P  +GA G  G  GP GP GP G  G PG  G  G P   G  GPPGA    G +G
Sbjct: 768 PIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKG 827

Query: 590 PKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPG----------PASYGRNGRDGERGPPG 638
             GD G KG+ GPPG  GP G PG IG  G PG          P + G  G  G  GPPG
Sbjct: 828 EPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPG 887

Query: 639 VAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPDP 678
            +G  G PGPPGP G  G   P   T  AG+      P P
Sbjct: 888 PSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGP 927



 Score =  525 bits (1353), Expect = e-149
 Identities = 307/692 (44%), Positives = 345/692 (49%), Gaps = 79/692 (11%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 85
            GPPGE+G PG  G PG  G+ G  G  G +G PGP GP G PG+ G PG+ G PGA GLT
Sbjct: 482  GPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLT 541

Query: 86   GPDGSPGS---------IGSKGQKGEPGVPGSRG------FPG-RGIPGPPGPPGTAGLP 129
            G  GSPG           G  G+ G PG PG+RG      FPG +G  G PG  G  G+P
Sbjct: 542  GSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVP 601

Query: 130  GELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACP-----PGRSGYPGLPG 184
            G  G VGP G  G  G  GPPGP GP G  G        P   P     PG +G PG  G
Sbjct: 602  GPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQG-----PAGSPGFQGLPGPAGPPGEAG 656

Query: 185  MRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARG 244
              G +G  G++G PG  G +GE G  GE G    QGPPG  G RG  G  G+ G KG  G
Sbjct: 657  KPGEQGVPGDLGAPGPSGARGERGFPGERG---VQGPPGPAGPRGANGAPGNDGAKGDAG 713

Query: 245  LDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDG 304
              G PG QG PG  G  G+RG  G  GPKGDRG  G +G  G PG  G  GL G  G  G
Sbjct: 714  APGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPG 773

Query: 305  IPGMPGTKGEPGKPGPPGDAGLQGLPG---VPGIPGAKGVAGEKGSTGAPGKPGQMGNSG 361
              G PG KGE G  GP G  G +G PG    PG PG  G AG  G+ G PG  G+ G++G
Sbjct: 774  PAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAG 833

Query: 362  KPGQQGPPGEVGPRGPQG---------LPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPG 412
              G  GPPG  GP GP G           G+RG  GP G+ G PG  G +G PG  G  G
Sbjct: 834  AKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAG 893

Query: 413  PPGLPGM------KGDRGVVG------EPGPKGEQGASGEEGEAGERGELGDIGLPGPKG 460
            PPG PG       KG RG  G      E GP G  G +GE+G  G  G  G  G PGP+G
Sbjct: 894  PPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQG 953

Query: 461  SAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIK 520
             AG  G  GL G  G RG PG+ GP G PG +G  G  G  G PG  GPPG A       
Sbjct: 954  IAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPG--- 1010

Query: 521  QVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKG 580
                                 +SG  G PG  G PG  G PG  G  G+ G  G PG  G
Sbjct: 1011 ---------------------ESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPG 1049

Query: 581  PPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGP-ASYGRNGRDGERGPPG 638
             PGA G  GP G  G++GE GP G  GP G  GA G  G  GP    G  G  G+RG  G
Sbjct: 1050 APGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKG 1109

Query: 639  VAGIPGVPGPPGPPGLPGFCEPASCTMQAGQR 670
              G  G+ GPPGPPG PG   P+  +  AG R
Sbjct: 1110 HRGFSGLQGPPGPPGSPGEQGPSGASGPAGPR 1141



 Score =  517 bits (1331), Expect = e-146
 Identities = 311/718 (43%), Positives = 353/718 (49%), Gaps = 76/718 (10%)

Query: 26  GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGL- 84
           GP G+ GP GP GP G PG DGI G  G  GPPGPPGP G PG  G      + G D   
Sbjct: 112 GPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKS 171

Query: 85  TGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTA---------GLPGELGR 134
           TG    PG +G  G +G PG PG+ G  G +G PG PG PG +         G PG+ G 
Sbjct: 172 TGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGD 231

Query: 135 VGPVGDPGRRGPPGPPGP------------PGPRGTIGFHDGDPLCPNACPPGRSGYP-- 180
            G  G PGR G  GPPGP            PG +G  GF   D    +A P G  G P  
Sbjct: 232 DGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGS 291

Query: 181 ----GLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGD 236
               G PG  G +G  GE G PG  G  G  G+ G  G  G  GP G  G  G  G VG 
Sbjct: 292 PGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGA 351

Query: 237 KGEKGARGLDGEPGPQGL---PGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGL------ 287
           KGE G +G  G  GPQG+   PG PG  G  GP G  G  G  GA+GA G PG+      
Sbjct: 352 KGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGF 411

Query: 288 ------PGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGV 341
                  GP+G  G PG  G  G PG PG+KG+ G  G PG  G+QG PG  G  G +G 
Sbjct: 412 PGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGA 471

Query: 342 AGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGS 401
            GE G TG PG PG+ G  G  G  G  G  GP+GP G  GS G  GP GSPG  G+ G 
Sbjct: 472 RGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGE 531

Query: 402 LGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGS 461
            G PG  GL G PG PG  G     G PGP G+ G  G  G  G RG+ G +G PGPKG+
Sbjct: 532 AGLPGAKGLTGSPGSPGPDGK---TGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGA 588

Query: 462 AGNPGE---------PGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGR 512
           AG PG+         PG  GP G  G  G +GP GP GP G +GEQG  G PG QG PG 
Sbjct: 589 AGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGP 648

Query: 513 APTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGI 572
           A       +   + +         S  R + G  G  G  GPPGP GP G NG PG  G 
Sbjct: 649 AGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGA 708

Query: 573 R------------GLPGIKGPP---GALGLRGPKGDLGE---KGERGPPGR-GPNGLPGA 613
           +            G PG++G P   GA GL GPKGD G+   KG  G PG+ G  GL G 
Sbjct: 709 KGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGP 768

Query: 614 IGLPGDPG-PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQR 670
           IG PG  G P   G +G  G  GP G  G PG  G PGPPG  GF  P     Q G +
Sbjct: 769 IGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAK 826



 Score =  413 bits (1062), Expect = e-115
 Identities = 244/550 (44%), Positives = 269/550 (48%), Gaps = 82/550 (14%)

Query: 24   QRGPPGEQGPPGP---PGPPGVPGIDGIDGDRGPKGPPGPPGPAG------------EPG 68
            + G PGEQG PG    PGP G  G  G  G+RG +GPPGP GP G            + G
Sbjct: 654  EAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAG 713

Query: 69   KPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----RGIPGPPGPPG 124
             PGAPG  G PG  G+ G  G+ G  G KG +G+ G  G+ G PG    RG+ GP GPPG
Sbjct: 714  APGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPG 773

Query: 125  TAGLPG---ELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPG 181
             AG PG   E G  GP G  G RG PG  G PGP G  GF         A PPG  G PG
Sbjct: 774  PAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGF---------AGPPGADGQPG 824

Query: 182  LPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQG------PPGAQGLRGITGIVG 235
              G  G  GAKG+ G PG  G  G  G  G +G  GA+G      PPGA G  G  G VG
Sbjct: 825  AKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVG 884

Query: 236  DKGEKGARGLDGEPGPQGLPGA------------PGDQGQRGPPGEAGPKGDRGAEGARG 283
              G  G  G  G PGP G  G             PG+ G  GPPG AG KG  GA+G  G
Sbjct: 885  PPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAG 944

Query: 284  IPGLPGP------KGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPG 337
             PG PGP      +G  GLPG  G  G PG+PG  GEPGK GP G +G +G PG  G PG
Sbjct: 945  APGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPG 1004

Query: 338  AKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGS-------------- 383
              G  GE G  GAPG  G  G  G PG +G  GE GP GP G PG+              
Sbjct: 1005 LAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSG 1064

Query: 384  -RGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGE------------PG 430
             RGE GP G  G  G +G+ G  G  G  G  G  G +GDRG+ G             PG
Sbjct: 1065 DRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPG 1124

Query: 431  PKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPG 490
              GEQG SG  G AG RG  G  G PG  G  G PG  G  GP G  G  G  GP GPPG
Sbjct: 1125 SPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPG 1184

Query: 491  PRGVQGEQGA 500
            P G  G   A
Sbjct: 1185 PPGPPGPPSA 1194



 Score =  201 bits (511), Expect = 2e-51
 Identities = 118/269 (43%), Positives = 136/269 (50%), Gaps = 37/269 (13%)

Query: 5    ARDRGALGLLLLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGP---PGPP 61
            A  RG +GL          QRG  G  G PGP G PG  G  G  G+RGP GP   PG  
Sbjct: 955  AGQRGVVGL--------PGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLA 1006

Query: 62   GPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPG 121
            GP GE G+ GAPG  G+PG       DGSPG+ G +G+ G  G PG+ G P  G PGP G
Sbjct: 1007 GPPGESGREGAPGAEGSPGR------DGSPGAKGDRGETGPAGPPGAPGAP--GAPGPVG 1058

Query: 122  PPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPG 181
            P G +G  GE G  GP G  G  G  GP GP GPRG                 G +G  G
Sbjct: 1059 PAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRG---------------DKGETGEQG 1103

Query: 182  LPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPP---GAQGLRGITGIVGDKG 238
              G++GH+G  G  G PG  G  GE+G  G  G  G +GPP   GA G  G+ G+ G  G
Sbjct: 1104 DRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIG 1163

Query: 239  EKGARGLDGEPGPQGLPGAPGDQGQRGPP 267
              G RG  G+ GP G PG PG  G  GPP
Sbjct: 1164 PPGPRGRTGDAGPVGPPGPPGPPGPPGPP 1192



 Score =  197 bits (502), Expect = 2e-50
 Identities = 130/328 (39%), Positives = 142/328 (43%), Gaps = 77/328 (23%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKG------PPGPPGPAGEPGKPGAPGK---P 76
            GP G  GPPGPPGP G  G  G  G+ GP G      PPGPPGPAGE G PGA G    P
Sbjct: 887  GPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAP 946

Query: 77   GTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----------RGIPGPPGPPGTA 126
            GTPG  G+ G  G  G  G +G++G PG+PG  G PG          RG PGP GPPG A
Sbjct: 947  GTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLA 1006

Query: 127  GLPGELGR------------------------VGPVGDPGRRGPPGPPGPPGPRGTIGFH 162
            G PGE GR                         GP G PG  G PG PGP GP G  G  
Sbjct: 1007 GPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDR 1066

Query: 163  DGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGE------------------PGRQGHK 204
                    A P G  G  G  G +G +G KGE GE                  PG  G  
Sbjct: 1067 GETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSP 1126

Query: 205  GEEGDQGELGEVGAQGPPGAQGLRGITGI---------------VGDKGEKGARGLDGEP 249
            GE+G  G  G  G +GPPG+ G  G  G+                GD G  G  G  G P
Sbjct: 1127 GEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPP 1186

Query: 250  GPQGLPGAPGD-QGQRGPPGEAGPKGDR 276
            GP G P A  D      PP E    G R
Sbjct: 1187 GPPGPPSAGFDFSFLPQPPQEKAHDGGR 1214



 Score =  122 bits (306), Expect = 1e-27
 Identities = 84/217 (38%), Positives = 95/217 (43%), Gaps = 57/217 (26%)

Query: 473 PEGSRG-----LPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVI 527
           P+GS         GVEGP+G  GPRG +G  G  G  G+ G PG                
Sbjct: 96  PDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPG---------------- 139

Query: 528 QEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENG-FPGQM---------GIRGLPG 577
                               LPG PGPPGPPGPPG  G F  Q+         G   +PG
Sbjct: 140 --------------------LPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPG 179

Query: 578 IKGPPGALGLRGPKGDLGEKGERGPPGR-GPNGLPGAIGLPGDPGPASYGRNGRDGERGP 636
             GP G  GL GP G  G +G +GPPG  G  G  G +G  G PGP   G+NG DGE G 
Sbjct: 180 PMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPP--GKNGDDGEAGK 237

Query: 637 PGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFN 673
           PG    PG  GPPGP G  G    A      G R F+
Sbjct: 238 PGR---PGERGPPGPQGARGLPGTAGLPGMKGHRGFS 271


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score =  536 bits (1382), Expect = e-152
 Identities = 329/738 (44%), Positives = 377/738 (51%), Gaps = 135/738 (18%)

Query: 25  RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGK---------PGAPGK 75
           +G  G  GP GPPG PG PG  G  G RGP+GPPG PG  GEPG+          G+PG 
Sbjct: 227 QGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGA 286

Query: 76  PGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGELGR 134
            G PGA GL G  G  G  G +G KGE G PGS+G  G  G  G  GP G  G+PGE GR
Sbjct: 287 RGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGR 346

Query: 135 VGPVGDPGRRGPPGPPGPPGPRGTIGFHD------------------------------- 163
           +GP G PG+RG  G PG PGP G +G                                  
Sbjct: 347 LGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGE 406

Query: 164 -------GDPLCPNAC-------------------PPGRSGYPGLPGMRGH---KGAKGE 194
                  G P  P A                    PPG +G PG PG +G    +G +G+
Sbjct: 407 TGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQ 466

Query: 195 IGEPGRQGHKGEEGDQGELGEVGAQGP---PGAQGLRG------ITGIVGDKGEKGARGL 245
            G+PG  G KGE G +GE G  G QGP   PG +G RG        G  G  GE+GA G 
Sbjct: 467 PGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGN 526

Query: 246 DGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGI 305
            G PG  GLPG  G QG+RGP G +GPKG +G  G  G PGLPG +G TG PGV G +G 
Sbjct: 527 RGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGK 586

Query: 306 PGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQ 365
            G  G  GE G+PGPPG  G++G PG  G+PG KG      S+G PGKPG+ GN+G PGQ
Sbjct: 587 LGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKG------SSGDPGKPGEAGNAGVPGQ 640

Query: 366 QGPPG---EVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGD 422
           +G PG   EVGP GP G PG  GE G  G PG        G  GLPG PGPPG  G  GD
Sbjct: 641 RGAPGKDGEVGPSGPVGPPGLAGERGEQGPPG------PTGFQGLPGPPGPPGEGGKPGD 694

Query: 423 RGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGV 482
           +GV G+PG  G  G  GE G  GERGE G  GLPG KG AG  G  G   P+GS G  G 
Sbjct: 695 QGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDG---PKGSPGPSGT 751

Query: 483 EGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPD 542
            G  GPPG +G+ GE+G  G PG +G  G               I E  AE  A     +
Sbjct: 752 PGDTGPPGLQGMPGERGIAGTPGPKGDRGG--------------IGEKGAEGTAG----N 793

Query: 543 SGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKG---------PPGALGLRGPKGD 593
            GA GLPG  GPPGP GP GE G PG  G+ G PG +G         P GA+G  GP+G 
Sbjct: 794 DGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGP 853

Query: 594 LGEKGERGPPG----RGPNGLPGAIGLPGDPGPASY----GRNGRDGERGPPGVAGIPGV 645
            G+ G +G PG    +G  G PG  GL G PGP       G  G  G +GPPG  G PG 
Sbjct: 854 DGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGS 913

Query: 646 P---GPPGPPGLPGFCEP 660
               GPPGP G PG   P
Sbjct: 914 AGRVGPPGPAGAPGPAGP 931



 Score =  521 bits (1343), Expect = e-148
 Identities = 325/738 (44%), Positives = 371/738 (50%), Gaps = 101/738 (13%)

Query: 25  RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGL 84
           RG PG  GPPG  GP G  G  G  G RGP+G  G PG  G+PG PG PG P  PG DGL
Sbjct: 128 RGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGL 187

Query: 85  TGPDGS------------------PGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTA 126
           + P  +                  PGS+G  G +G  G+ G +G  G G  GPPG PG  
Sbjct: 188 SRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQG--GAGPTGPPGEPGDP 245

Query: 127 GLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMR 186
           G  G +G  GP G PG+ G  G PG  G  G +GF  G P       PG  G PGL G R
Sbjct: 246 GPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGF-AGSPGARGF--PGAPGLPGLKGHR 302

Query: 187 GHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLD 246
           GHKG +G  GE G  G KGE G  G +G +G  GP G  G RG  G  G  G++GA G+ 
Sbjct: 303 GHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMP 362

Query: 247 GEPGPQ---GLPGAPGDQGQRGPPGEAGPKGDRGAE---GARGIPGLPGPKGDTGLPGVD 300
           G+PGP    G+PG+ G  G  G  GEAGP G RG E   G RG  G PGP G  GLPG  
Sbjct: 363 GKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAI 422

Query: 301 GRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNS 360
           G DG PG  G  G PG  GPPG AG  G PG  G  G +G+ G+ G  G PG  G+ G  
Sbjct: 423 GTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPK 482

Query: 361 GKPGQQ------GPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGL---- 410
           G+PG        GPPGE G RGP+G PG+ G  GPVG  G PG  G  GS GLPG     
Sbjct: 483 GEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQ 542

Query: 411 -----------------PGPPGLPGMKGDRGVVGEPGPKGEQ------GASGEEGEAGE- 446
                            PG PG PG+ G RG+ G PG +G +      GA GE+G  G  
Sbjct: 543 GERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPP 602

Query: 447 -----RGELGDIGLPGPKGSAGNPGEP---GLRGPEGSRGLPGVE------GPRGPPGPR 492
                RG+ G +GLPGPKGS+G+PG+P   G  G  G RG PG +      GP GPPG  
Sbjct: 603 GSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLA 662

Query: 493 GVQGEQGA------TGLPGVQGPPGRA--PTDQHIKQVCMRV-IQEHFAEMAASLKRPDS 543
           G +GEQG        GLPG  GPPG    P DQ +      V       E     +R + 
Sbjct: 663 GERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEP 722

Query: 544 GATGLPGRP------GPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGD---L 594
           G TGLPG        GP GP G PG +G PG  G  GL G+ G  G  G  GPKGD   +
Sbjct: 723 GITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGI 782

Query: 595 GEKGERGPPGR-GPNGLPGAIGLPGDPGPASYGRNGRDGER---GPPGVAGIPGVPGPPG 650
           GEKG  G  G  G  GLPG +G PG  GP   G  G  G R   GPPG  G PG  G  G
Sbjct: 783 GEKGAEGTAGNDGARGLPGPLGPPGPAGPT--GEKGEPGPRGLVGPPGSRGNPGSRGENG 840

Query: 651 PPGLPGFCEPASCTMQAG 668
           P G  GF  P     Q G
Sbjct: 841 PTGAVGFAGPQGPDGQPG 858



 Score =  521 bits (1342), Expect = e-148
 Identities = 308/680 (45%), Positives = 344/680 (50%), Gaps = 49/680 (7%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPG---------PAGEPGKPGAPGKP 76
            G PG  GPPG  GPPG PG  G  G +G +G PG PG         P GEPG  G  G  
Sbjct: 435  GSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPI 494

Query: 77   GTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR-GIPGPPGPPGTAGLPGELGRV 135
            G PG +G  GP G PG++G  G  GE G PG+RGFPG  G+PGP G  G  G  G  G  
Sbjct: 495  GPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPK 554

Query: 136  GPVGDPGRRGPPGPPGP---------PGPRGTIG-----FHDGDPLCPNACP-PGRSGYP 180
            G  GDPGR G PG PG           GP G +G       DG P  P +    G+ G  
Sbjct: 555  GSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSM 614

Query: 181  GLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEK 240
            GLPG +G  G  G+ GE G  G  G+ G  G+ GEVG  GP G  GL G  G  G  G  
Sbjct: 615  GLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPT 674

Query: 241  GARGLDGEPGPQGLPGAPGDQGQRGPPGEAGP---KGDRGAEGARGIPGLPGPKGDTGLP 297
            G +GL G PGP G  G PGDQG  G PG  GP   +G+RG  G RG PG+ G  G+ G+ 
Sbjct: 675  GFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMA 734

Query: 298  GVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQM 357
            G  G DG  G PG  G PG  GPPG  G+ G  G+ G PG KG  G  G  GA G  G  
Sbjct: 735  GGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGND 794

Query: 358  GNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLP 417
            G  G PG  GPPG  GP G +G PG RG +GP GS G PG  G  G  G  G  GP G  
Sbjct: 795  GARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPD 854

Query: 418  GMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSR 477
            G  G +G  GEPG KG+ G+ G +G AG  G  G  G+PG KG  G  G PG  G  GS 
Sbjct: 855  GQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSA 914

Query: 478  GLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAAS 537
            G  G  GP G PGP G  GE G  G PG++G PG             RV     A     
Sbjct: 915  GRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHG----------RVGDRGPAGPPGG 964

Query: 538  LKRPDSGATGLPGRPGPPGPPGPPGENG------FPGQMGIRGLPGIKGPPGALGLRGPK 591
                D G  G  G+PGP GPPGP G  G       PGQ G RG+PG+ GP G  G  GP 
Sbjct: 965  --PGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPT 1022

Query: 592  GDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASY-GRNGRDGERGPPGVAGIPGVPGPPG 650
            G  G+KG  GP G  P G  G +G PG  GPA   G  GRDG  G  G  G PG  G PG
Sbjct: 1023 GATGDKGPPGPVG--PPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPG 1080

Query: 651  PPGLPGFCEPASCTMQAGQR 670
              G PG   P      AGQR
Sbjct: 1081 SQGAPGTPGPVGAPGDAGQR 1100



 Score =  516 bits (1329), Expect = e-146
 Identities = 316/713 (44%), Positives = 367/713 (51%), Gaps = 99/713 (13%)

Query: 25   RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGL 84
            +G  GE GPPGP G PG+PG  G DG  G KGP G PG +G PG  G PG PG       
Sbjct: 401  QGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPG------- 453

Query: 85   TGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGELGRVGPVGDPGR 143
              P GS G  G +GQ G+PGVPG +G  G +G PGP G  G  G PGE G+ GP GDPG 
Sbjct: 454  --PQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGT 511

Query: 144  RGPPGPPGPPGPRGTIGFHDGDPL------------CPNACPPGRSGYPGLPGMRGHKGA 191
             GPPGP G  G  G  GF   D L              ++ P G  G PG PG  G  GA
Sbjct: 512  VGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGA 571

Query: 192  KGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGP 251
            +G  G PG QG +G+ G  G  GE G  GPPG+ G+RG  G +G  G KG+ G  G+PG 
Sbjct: 572  RGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGE 631

Query: 252  QGLPGAPGDQGQR------------GPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGV 299
             G  G PG +G              GPPG AG +G++G  G  G  GLPGP G  G  G 
Sbjct: 632  AGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGK 691

Query: 300  DGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVA---GEKGSTGAPGKPGQ 356
             G  G+PG PG  G  G  G  G+ G +G PG+ G+PG KG+A   G  G  G+PG  G 
Sbjct: 692  PGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGT 751

Query: 357  MGNSGKPGQQGPPGE------VGPRGPQ------------GLPGSRGELGPVGSPGLPGK 398
             G++G PG QG PGE       GP+G +            G  G+RG  GP+G PG  G 
Sbjct: 752  PGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGP 811

Query: 399  LGSLGSPGLPGLPGPPGLPGMKGDR------GVVGEPGPKGEQGASGEEGEAGERGELGD 452
             G  G PG  GL GPPG  G  G R      G VG  GP+G  G  G +GE GE G+ GD
Sbjct: 812  TGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGD 871

Query: 453  IGLPGPKGSAGNPGE------PGLR------GPEGSRGLPGVEGPRGPPGPRGVQGEQGA 500
             G PGP+G AG+PG       PGL+      GP G+ G PG  G  GPPGP G  G  G 
Sbjct: 872  AGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGP 931

Query: 501  TGLPGVQGPPG-RAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPG 559
             G PG +GPPG R     H      RV     A         D G  G  G+PGP GPPG
Sbjct: 932  LGEPGKEGPPGLRGDPGSH-----GRVGDRGPAGPPGG--PGDKGDPGEDGQPGPDGPPG 984

Query: 560  PPGEN------GFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGA 613
            P G        G PGQ G RG+PG+ GP G  G  GP G  G+KG  GP   GP G  G 
Sbjct: 985  PAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPV--GPPGSNGP 1042

Query: 614  IGLPGDPGPA-SYGRNGRD------GERGPPGVAGIP---GVPGPPGPPGLPG 656
            +G PG  GPA + G  GRD      G+RG PG AG+P   G PG PGP G PG
Sbjct: 1043 VGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPG 1095



 Score =  506 bits (1303), Expect = e-143
 Identities = 304/698 (43%), Positives = 349/698 (50%), Gaps = 83/698 (11%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGT------P 79
            GP G QG PG PG PG+PG  G+ G+ G +GP G  GP G PG+ G PG PG+      P
Sbjct: 552  GPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQP 611

Query: 80   GADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR-GIPGPPGPPGTAGLPGELGRVGPV 138
            G+ GL GP GS G  G  G+ G  GVPG RG PG+ G  GP GP G  GL GE G  GP 
Sbjct: 612  GSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPP 671

Query: 139  GDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEP 198
            G  G +G PGPPGPPG  G                PG  G PG PG  G  G +GE G P
Sbjct: 672  GPTGFQGLPGPPGPPGEGGK---------------PGDQGVPGDPGAVGPLGPRGERGNP 716

Query: 199  GRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAP 258
            G +G  G  G  GE G  G  GP G +G  G +G  GD G  G +G+   PG +G+ G P
Sbjct: 717  GERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGM---PGERGIAGTP 773

Query: 259  GDQGQRGPPGEAGPKGDRGAEGARGIPGL---PGPKGDTGLPGVDGRDGIPGMPGTKGEP 315
            G +G RG  GE G +G  G +GARG+PG    PGP G TG  G  G  G+ G PG++G P
Sbjct: 774  GPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNP 833

Query: 316  GK------------PGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKP 363
            G              GP G  G  G+ G PG PG KG AG  G  G  G PG  G +G P
Sbjct: 834  GSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVP 893

Query: 364  GQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGL---PGLPGPPGLPGMK 420
            G +G  G  GP G  G PGS G +GP G  G PG  G LG PG    PGL G PG  G  
Sbjct: 894  GLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRV 953

Query: 421  GDRGVVGEPGPKGEQGASGEEGE---------AGERGELGDIGLPGPKGSAGNPGEPGLR 471
            GDRG  G PG  G++G  GE+G+         AG  G+ G +G+PG +G  G PG PG  
Sbjct: 954  GDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPA 1013

Query: 472  GPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHF 531
            G  G  G  G  G +GPPGP G  G  G  G PG +GP G   T      V  R      
Sbjct: 1014 GTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERG----- 1068

Query: 532  AEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRG-- 589
                    R D G  GLPG  G PG PGP G  G  GQ G  G  G  GPPG  G RG  
Sbjct: 1069 -------DRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLP 1121

Query: 590  ----PKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPG 644
                P+GD G+ G+RG  G +G  G  G  GLPG PGP     NG  G  G PG  G  G
Sbjct: 1122 GPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGP-----NGEQGSAGIPGPFGPRG 1176

Query: 645  VPGP------PGPPGLPGFCEPASCTMQAGQRAFNKGP 676
             PGP       G PG  G   P       G+ A  +GP
Sbjct: 1177 PPGPVGPSGKEGNPGPLGPIGPPGVRGSVGE-AGPEGP 1213



 Score =  499 bits (1285), Expect = e-141
 Identities = 301/674 (44%), Positives = 347/674 (51%), Gaps = 83/674 (12%)

Query: 26   GPPGEQGPPGPPGPPGV---PGIDGIDGDRGPKGPPGPPGPAGE---PGKPGAPGKPGTP 79
            G PGE G PGPPG  G+   PG  G+ G +G  G PG PG AG    PG+ GAPGK    
Sbjct: 591  GAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGK---- 646

Query: 80   GADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTA------GLPGELG 133
              DG  GP G  G  G  G++GE G PG  GF  +G+PGPPGPPG        G+PG+ G
Sbjct: 647  --DGEVGPSGPVGPPGLAGERGEQGPPGPTGF--QGLPGPPGPPGEGGKPGDQGVPGDPG 702

Query: 134  RVGPV------GDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACP-----PGRSGYPGL 182
             VGP+      G+PG RG PG  G PG +G  G H  D   P   P     PG +G PGL
Sbjct: 703  AVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDG--PKGSPGPSGTPGDTGPPGL 760

Query: 183  PGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGA 242
             GM G +G  G  G  G +G  GE+G +G  G  GA+G PG  G  G  G  G+KGE G 
Sbjct: 761  QGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGP 820

Query: 243  RGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGR 302
            RGL G PG +G PG+ G+ G  G  G AGP+G  G  G +G PG PG KGD G P   G 
Sbjct: 821  RGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSP---GP 877

Query: 303  DGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGK 362
             G+ G PG  G  G PG  G  G QG PG  G PG+ G  G  G  GAPG  G +   G+
Sbjct: 878  QGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPL---GE 934

Query: 363  PGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGD 422
            PG++GPP   G RG  G  G  G+ GP G PG PG  G  G  G PG  GPPG  G  G 
Sbjct: 935  PGKEGPP---GLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQ 991

Query: 423  RGVVGEPGPKGEQGASGEEGEAGERGELGDIGLP---------GPKGSAGNPGEPGLRGP 473
            RG+VG PG +GE+G  G  G AG  G++G  G           GP GS G  GEPG  GP
Sbjct: 992  RGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGP 1051

Query: 474  EGSRGLPGVE------GPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVI 527
             G+ G PG +      G RG PGP G+ G QGA G PG  G PG A              
Sbjct: 1052 AGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDA-------------- 1097

Query: 528  QEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGL 587
                 +      R   G  G  G+ G PGP GP G+ G  G  G RG  G +G  G  GL
Sbjct: 1098 ----GQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGL 1153

Query: 588  RGPKGDLGEKGERGPPG----RGPNGLPGAIGLPGDPGP----ASYGRNGRDGERGPPGV 639
             GP G  GE+G  G PG    RGP G  G  G  G+PGP       G  G  GE GP G 
Sbjct: 1154 PGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGP 1213

Query: 640  AGIPGVPGPPGPPG 653
             G PG PGPPGPPG
Sbjct: 1214 PGEPGPPGPPGPPG 1227



 Score =  414 bits (1063), Expect = e-115
 Identities = 278/680 (40%), Positives = 313/680 (46%), Gaps = 110/680 (16%)

Query: 95  GSKGQKGEPG-VPGSRGFPGRGIPGPPGPPGTAGLPGELG---RVGPVGDPGRRGPPGPP 150
           G KGQKGEPG VP   G  GR  PGP GPPG+ G  GE G   R GP G  G  G PG P
Sbjct: 110 GRKGQKGEPGLVPVVTGIRGR--PGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVP 167

Query: 151 GPPGPRGTIGFHDGDPLCPNACPPGRSGYPGL-------------PGMRGHKGAKGEIGE 197
           G PG  G  G H   P       P  +   GL             PG  G  G +G  G 
Sbjct: 168 GQPGAPGPPG-HPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGL 226

Query: 198 PGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGA 257
            G+QG  G  G  GE G+ G  GP G++G  G  G  G+ GE G  G  GE G  G PGA
Sbjct: 227 QGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGA 286

Query: 258 PGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGK 317
            G  G  G PG  G +G +G EG +G  G PG KG+ G  G  G  G  G  G  GE G+
Sbjct: 287 RGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGR 346

Query: 318 PGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPP------GE 371
            GP G  G +G  G+PG PG  G  G  GS+G PG PG  G +G  G +GP       GE
Sbjct: 347 LGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGE 406

Query: 372 VGPRGPQGLPGSRGEL---------GPVGSPGLPGKLGSLGSPGLP------------GL 410
            GP GP G PG  G +         GP GSPG  G  GS G PG P            G 
Sbjct: 407 TGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQ 466

Query: 411 PGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGL 470
           PG PG+PG KG+ G  GEPGP G QG  G  GE G+RG  GD G  GP G  G  G PG 
Sbjct: 467 PGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGN 526

Query: 471 RGPEGSRGLP---GVEGPRGP---------------PGPRGVQGEQGATGLPGVQGPPGR 512
           RG  GS GLP   G +G RGP               PG  G+ G +G TG PGVQGP G+
Sbjct: 527 RGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGK 586

Query: 513 -----APTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFP 567
                AP +                   +   R   G+ GLPG  G  G PG PGE G  
Sbjct: 587 LGPLGAPGE-----------DGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNA 635

Query: 568 GQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-------------RGPNGLPGAI 614
           G  G RG PG  G  G  G  GP G  GE+GE+GPPG              G  G PG  
Sbjct: 636 GVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQ 695

Query: 615 GLPGDPGPAS----YGRNGRDGERGPPGVAGIP------------GVPGPPGPPGLPGFC 658
           G+PGDPG        G  G  GERG PG+ G+P            G  G PGP G PG  
Sbjct: 696 GVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDT 755

Query: 659 EPASCTMQAGQRAFNKGPDP 678
            P       G+R     P P
Sbjct: 756 GPPGLQGMPGERGIAGTPGP 775



 Score =  378 bits (970), Expect = e-104
 Identities = 234/558 (41%), Positives = 277/558 (49%), Gaps = 86/558 (15%)

Query: 165 DPLCP-NACPPGRSGYPGLPGMRGHKGAKGEIGEP----------GRQGHKGEEGDQGEL 213
           DP+ P   C P  S  PG       +G KG+ GEP          GR G  G  G QG  
Sbjct: 84  DPVTPPGECCPVCSQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPR 143

Query: 214 GEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDG---EPGPQGL---------------- 254
           GE G +G PG +G +GI G  G  G+ GA G  G    PGP GL                
Sbjct: 144 GERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSG 203

Query: 255 --------PGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIP 306
                   PG+ G  G RGP G  G +G  G  G  G PG PGP G  G  G +G    P
Sbjct: 204 LGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGP---P 260

Query: 307 GMPGTKGEPGKPGPPGDAGL------QGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNS 360
           G PG  GEPG+ G PG+ G       +G PG PG+PG KG  G KG  G  G+ G  G+ 
Sbjct: 261 GKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSK 320

Query: 361 GKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSP------GLPGKLGSLGSPGLPGLPGPP 414
           G+ G  GP G +GP GP+G+PG RG LGP G+P      G+PGK G +G  G+PG  G P
Sbjct: 321 GEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFP 380

Query: 415 GLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNP------GEP 468
           G PGMKG+ G  G  GP+G Q   G+ GE G  G +G  GLPG  G+ G P      G P
Sbjct: 381 GNPGMKGEAGPTGARGPEGPQ---GQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSP 437

Query: 469 GLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPG-RAPTDQHIKQVCMRVI 527
           G  GP GS G PG  GP+G  GP+G++G+ G  G+PG +G  G +     H         
Sbjct: 438 GTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPH--------- 488

Query: 528 QEHFAEMAASLKRP-DSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALG 586
                 +   +  P + G  G  G PG  GPPGP GE G PG  G  G  G+ GP GA G
Sbjct: 489 -----GIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQG 543

Query: 587 LRGPKGDLGEKGERGPPGR-GPNGLPGAIGLPGDPGP-------ASYGRNGRDGERGPPG 638
            RGP G  G KG +G PGR G  GLPGA GL G+PG           G  G DG  GPPG
Sbjct: 544 ERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPG 603

Query: 639 VAGIPGVPGPPGPPGLPG 656
             GI G PG  G PG  G
Sbjct: 604 SIGIRGQPGSMGLPGPKG 621



 Score =  367 bits (942), Expect = e-101
 Identities = 217/497 (43%), Positives = 246/497 (49%), Gaps = 67/497 (13%)

Query: 22   AAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPP---GPPGPAGEP----------- 67
            A   GP G++G  G  G  G  G DG  G  GP GPP   GP G  GEP           
Sbjct: 770  AGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGS 829

Query: 68   -GKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----RGIPGPPGP 122
             G PG+ G+ G  GA G  GP G  G  G KG+ GEPG  G  G PG     G PGP GP
Sbjct: 830  RGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGP 889

Query: 123  PGTAGLPGELGRVGP------VGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGR 176
             G  GL G  G  GP       G  GR GPPGP G PGP G +G             PG+
Sbjct: 890  NGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLG------------EPGK 937

Query: 177  SGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGD 236
             G PGL G  G  G  G+ G  G  G  G++GD GE G+ G  GPPG  G  G  GIVG 
Sbjct: 938  EGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGM 997

Query: 237  KGEKGARGLDGEPGPQGLP---GAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGD 293
             G++G RG+ G PGP G P   G  G  G +GPPG  GP            PG  GP G+
Sbjct: 998  PGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGP------------PGSNGPVGE 1045

Query: 294  TGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGK 353
             G  G  G DG PG  G  GE G  G PG AGL G  G PG PG  G  G+ G  G PG 
Sbjct: 1046 PGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGS 1105

Query: 354  PGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGP 413
             G +G  G+ G++G PG  GPRG +G  G RG+          G+ G  G  GL GLPGP
Sbjct: 1106 RGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGD---------RGQKGHRGFTGLQGLPGP 1156

Query: 414  PGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGP 473
            PG  G +G  G+ G  GP+G  G  G  G+ G  G LG IG PG +GS G        GP
Sbjct: 1157 PGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGE------AGP 1210

Query: 474  EGSRGLPGVEGPRGPPG 490
            EG  G PG  GP GPPG
Sbjct: 1211 EGPPGEPGPPGPPGPPG 1227



 Score =  337 bits (864), Expect = 2e-92
 Identities = 205/495 (41%), Positives = 237/495 (47%), Gaps = 85/495 (17%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 85
            GP G  GP G PG  G PG+ G+ G+RG  G PGP G  G  G+ GA G  G  GA GL 
Sbjct: 741  GPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLP 800

Query: 86   GPDGSPGSIGSKGQKGEPGV------PGSRGFPGR-------------GIPGPPGPPGTA 126
            GP G PG  G  G+KGEPG       PGSRG PG              G  GP G PG  
Sbjct: 801  GPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVK 860

Query: 127  GLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGL---- 182
            G PGE G+ G  G PG +G  G PGP GP G  G   G        PPG +G+PG     
Sbjct: 861  GEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRG---TQGPPGATGFPGSAGRV 917

Query: 183  --PGMRGHKGAKGEIGEPGRQGHKG------------------------EEGDQGELGEV 216
              PG  G  G  G +GEPG++G  G                        ++GD GE G+ 
Sbjct: 918  GPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQP 977

Query: 217  GAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDR 276
            G  GPPG  G  G  GIVG  G++G RG+ G PGP G PG  G  G  G  G  GP G  
Sbjct: 978  GPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPP 1037

Query: 277  GAEGARGIPGLPGPKGDTGLPGVDGR---------DGIPGMPGTKGEPGKPGP---PGDA 324
            G+ G  G PG  GP G+ G PG DG           G  G+PG++G PG PGP   PGDA
Sbjct: 1038 GSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDA 1097

Query: 325  GLQGLPGVPG------------IPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEV 372
            G +G PG  G            +PG +G  G+KG  G  G  GQ G+ G  G QG PG  
Sbjct: 1098 GQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPP 1157

Query: 373  GPRGPQGLPGSRGELGPVGSPGL---------PGKLGSLGSPGLPGLPGPPGLPGMKGDR 423
            GP G QG  G  G  GP G PG          PG LG +G PG+ G  G  G  G  G+ 
Sbjct: 1158 GPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEP 1217

Query: 424  GVVGEPGPKGEQGAS 438
            G  G PGP G   A+
Sbjct: 1218 GPPGPPGPPGHLTAA 1232



 Score =  328 bits (840), Expect = 1e-89
 Identities = 192/415 (46%), Positives = 220/415 (53%), Gaps = 19/415 (4%)

Query: 17   GLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKP 76
            GL      RG PG +G  GP G  G  G  G DG  G KG PG PG  G+ G PG  G  
Sbjct: 822  GLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLA 881

Query: 77   GTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR-GIPGPPGPPGTAGLPGELGRV 135
            G+PG     GP+G PG  G +G +G PG  G  G  GR G PGP G PG AG  GE G+ 
Sbjct: 882  GSPGPH---GPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKE 938

Query: 136  GPV---GDPGR------RGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMR 186
            GP    GDPG       RGP GPPG PG +G  G  DG P  P+  PPG +G  G  G+ 
Sbjct: 939  GPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPG-EDGQP-GPDG-PPGPAGTTGQRGIV 995

Query: 187  GHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLD 246
            G  G +GE G PG  G  G  G  G  G  G +GPPG  G  G  G VG+ G +G  G D
Sbjct: 996  GMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGND 1055

Query: 247  GEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIP 306
            G PG     GA G++G RG PG AG  G +GA G  G  G PG  G  G PG  G  G P
Sbjct: 1056 GTPGRD---GAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPP 1112

Query: 307  GMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQ 366
            G  G +G PG  GP GD G  G  G  G  G +G  G +G  G PG  G+ G++G PG  
Sbjct: 1113 GRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPF 1172

Query: 367  GPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKG 421
            GP G  GP GP G  G+ G LGP+G PG+ G +G  G  G PG PGPPG PG  G
Sbjct: 1173 GPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPG 1227



 Score =  206 bits (524), Expect = 6e-53
 Identities = 121/270 (44%), Positives = 134/270 (49%), Gaps = 31/270 (11%)

Query: 2    AWTARDRGALGLLLLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPP 61
            A T   RG +G+          QRG  G  G PGP G PG  G  G  GD+GP GP GPP
Sbjct: 986  AGTTGQRGIVGM--------PGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPP 1037

Query: 62   ---GPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPG 118
               GP GEPG  G  G  GTPG       DG+ G  G +G  G  G+PGS+G P  G PG
Sbjct: 1038 GSNGPVGEPGPEGPAGNDGTPGR------DGAVGERGDRGDPGPAGLPGSQGAP--GTPG 1089

Query: 119  PPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSG 178
            P G PG AG  G+ G  GP+G PGR G  G PGP GPRG  G H            G  G
Sbjct: 1090 PVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDH------------GDRG 1137

Query: 179  YPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKG 238
              G  G RG  G +G  G PG  G +G  G  G  G  G  GP G  G  G  G +G  G
Sbjct: 1138 DRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIG 1197

Query: 239  EKGARGLDGEPGPQGLPGAPGDQGQRGPPG 268
              G RG  GE GP+G PG PG  G  GPPG
Sbjct: 1198 PPGVRGSVGEAGPEGPPGEPGPPGPPGPPG 1227



 Score =  134 bits (336), Expect = 4e-31
 Identities = 78/159 (49%), Positives = 84/159 (52%), Gaps = 19/159 (11%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 85
            G PG QG PG PGP G PG  G  GD G +GP GPPG AG+ G PG  G  G  G  G  
Sbjct: 1077 GLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDR 1136

Query: 86   GPDGSPGSIGSKGQKGEPGVPG------SRGFPG----RGIPGPPGPPGTAGLPGELGRV 135
            G  G  G  G  G +G PG PG      S G PG    RG PGP GP G  G PG LG +
Sbjct: 1137 GDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPI 1196

Query: 136  GP------VGDPGRRGPPG---PPGPPGPRGTIGFHDGD 165
            GP      VG+ G  GPPG   PPGPPGP G +    GD
Sbjct: 1197 GPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAALGD 1235



 Score = 90.5 bits (223), Expect = 5e-18
 Identities = 56/132 (42%), Positives = 62/132 (46%), Gaps = 28/132 (21%)

Query: 22   AAQRGPPGEQGPPGPPGPPG------------VPGIDGIDGDRGPKGP------PGPPGP 63
            A +RG PG QGP G  G  G              G+ G+ G  GP G       PGP GP
Sbjct: 1115 AGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGP 1174

Query: 64   AGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPP 123
             G PG  G  GK G PG  G  GP G  GS+G  G +G PG PG         PGPPGPP
Sbjct: 1175 RGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGP--------PGPPGPP 1226

Query: 124  G--TAGLPGELG 133
            G  TA L   +G
Sbjct: 1227 GHLTAALGDIMG 1238


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score =  534 bits (1376), Expect = e-152
 Identities = 313/672 (46%), Positives = 351/672 (52%), Gaps = 76/672 (11%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 85
            GP G  G  GP GPPG  G +G  G  G  GP GPPGP G+ G PG PG+ G  G  G T
Sbjct: 931  GPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKT 990

Query: 86   GPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRG 145
            GP G PG +G +G  GE G  G RG PG     PPGPPG  GLPG  G+ G  GDPG  G
Sbjct: 991  GPPGPPGVVGPQGPTGETGPMGERGHPG-----PPGPPGEQGLPGLAGKEGTKGDPGPAG 1045

Query: 146  PPGPPGPPGPRGTIGFHDGDP-------LCPNACPPGRSGYPGLPGMRGHKGAKGEIGEP 198
             PG  GPPG RG  G   G P       L  N  PPG  G  G PG RG  GA G IG P
Sbjct: 1046 LPGKDGPPGLRGFPGDR-GLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIP 1104

Query: 199  GR---QGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLP 255
            GR   QG  G  G++G  GE G QGP G  GL+G  G+ G  G  G  G DG+ G  G P
Sbjct: 1105 GRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEP 1164

Query: 256  G---APGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGL---PGVDGRDGIPGMP 309
            G   + GD+G++GPPG  GP+G  G  G  G  G PGP+G  GL    G +G  G PG P
Sbjct: 1165 GQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPP 1224

Query: 310  GTKGEPGKPGPPG------DAGLQGLPGVPG------IPGAKGVAGEKGSTGAPGKPGQM 357
            G  G  G PGPPG      D G  G PG PG       PGA G  G  G  G PG  G+ 
Sbjct: 1225 GPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEK 1284

Query: 358  GNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLP 417
            G  G+ G+ G PGE GP GP+G  G +GE GP G+ G PG  G  G  G  G PGP G P
Sbjct: 1285 GEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFP 1344

Query: 418  GMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSR 477
            G   D G  GEPGP G+ G  G++G+ GE G+ G    PGP G  G  G PG RGP G  
Sbjct: 1345 G---DPGPPGEPGPAGQDGPPGDKGDDGEPGQTGS---PGPTGEPGPSGPPGKRGPPGPA 1398

Query: 478  GLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAAS 537
            G  G +G +G  G  G++G  G TG  G QG PG+   D       +R I     E    
Sbjct: 1399 GPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDG------LRGIPGPVGEQ--- 1449

Query: 538  LKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEK 597
                     GLPG PGP GPPGP G  G PG  G  G  G KG PG +GL GP G+ GEK
Sbjct: 1450 ---------GLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEK 1500

Query: 598  GERGPPG----------------RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAG 641
            G+RG PG                 GP G PG  GLPG PGP   G  G  G  GP G AG
Sbjct: 1501 GDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPK--GAKGSSGPTGPKGEAG 1558

Query: 642  IPGVPGPPGPPG 653
             PG PGPPGPPG
Sbjct: 1559 HPGPPGPPGPPG 1570



 Score =  531 bits (1369), Expect = e-151
 Identities = 323/753 (42%), Positives = 379/753 (50%), Gaps = 137/753 (18%)

Query: 4    TARDRGALGLLLLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGP---PGP 60
            +A++  A  +L           GP G  G PGP GPPG  G+ G  GD GP+GP    GP
Sbjct: 540  SAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGP 599

Query: 61   PGPAGEPGK------------PGAPGKPGTPGADGLT------------GPDGSPGSIGS 96
            PGPAG+PG+            PG  G  G  G DGL             GP G PG  G 
Sbjct: 600  PGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGD 659

Query: 97   KGQKGEPGVPGSRGFPG----------RGIPGPPGPPGTAGL---PGELGRVGPVGD--- 140
             G++G+ G  G RG PG          +G PGPPGPPG  G+   PG  G VGP G+   
Sbjct: 660  DGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGP 719

Query: 141  PGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGR 200
            PG++G PG  G PGP+G IG            PPG  G  G PG+ G  GA G  G PG+
Sbjct: 720  PGQQGNPGAQGLPGPQGAIG------------PPGEKGPLGKPGLPGMPGADGPPGHPGK 767

Query: 201  QGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGD 260
            +G  GE+G QG  G  G  G PG +G++G  GI G KG KG +G DG PG +G  G  GD
Sbjct: 768  EGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGD 827

Query: 261  QGQRGPP---GEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGK 317
            +G+ GPP   GE GP+G +G  G  G PG  GP G+ G  GV G  G PG  G KG  G 
Sbjct: 828  RGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGF 887

Query: 318  PGPPGDAGLQGLPGVPGIPGAK------GVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGE 371
            PG PG  G +G  G PG PG +      G  GE+G  G  GKPG  GNSG  G  GPPGE
Sbjct: 888  PGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGE 947

Query: 372  VGPRGPQ---GLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGE 428
             GP GPQ   G PG +G  GP G  GLPG  G  G  G  G  GPPG PG+ G +G  GE
Sbjct: 948  RGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGE 1007

Query: 429  PGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGP 488
             GP GE+G  G  G  GE+G  G  G  G KG  G  G PG  GP G RG PG  G  GP
Sbjct: 1008 TGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGP 1067

Query: 489  PGPRGVQGEQGATGLPGVQGPPG-RAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATG 547
             G  G++G +G  G PG  G PG R P                            +G  G
Sbjct: 1068 VGALGLKGNEGPPGPPGPAGSPGERGPAGA-------------------------AGPIG 1102

Query: 548  LPGRPGPPGPPGPPGENGFPGQMGIR------------GLPGIKGPPGALGLRGPKGDLG 595
            +PGRPGP GPPGP GE G PG+ G +            GLPG  GP G  G  G KG++G
Sbjct: 1103 IPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIG 1162

Query: 596  E---------KGERGPPG----RGPNGLPGAIGLPGDPGPAS----YGRNGRDGER---G 635
            E         KGE+GPPG    +GP G PG  G  G+PGP      +G+ G +G R   G
Sbjct: 1163 EPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPG 1222

Query: 636  PPGVAGIPGVPGPP------------GPPGLPG 656
            PPG  G+ G+PGPP            GPPG PG
Sbjct: 1223 PPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPG 1255



 Score =  529 bits (1362), Expect = e-150
 Identities = 318/745 (42%), Positives = 365/745 (48%), Gaps = 116/745 (15%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPK---GPPGPPGPAGEPGKPGAPGKPGTPGA- 81
            GP G  GP GPPGPPG PG+ G+DG  GPK   GP G PGP G+ G PGA G PG  GA 
Sbjct: 679  GPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAI 738

Query: 82   --DGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLP--------- 129
               G  GP G PG  G  G  G PG PG  G PG +G  GPPGP G  G P         
Sbjct: 739  GPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGAD 798

Query: 130  ------------------------------GELGRVGPVGDPGRRGP---------PGPP 150
                                          GE+G  GP G+ G  GP         PGP 
Sbjct: 799  GIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPL 858

Query: 151  GPPGPRGTIGFHDGDPLCP-NACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGD 209
            GPPG +G +G   G P  P    P G  G+PG PG  G KG +G  G+PG +G +G  G 
Sbjct: 859  GPPGEKGKLGV-PGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGP 917

Query: 210  QGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGE---PGPQGLPGAPGD------ 260
            +GE G  G  G PG +G  G  G  G  GE+G  G  G    PGP+G PG PG       
Sbjct: 918  RGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGH 977

Query: 261  ---------QGQRGPP------GEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGI 305
                     QG+ GPP      G  GP G+ G  G RG PG PGP G+ GLPG+ G++G 
Sbjct: 978  PGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGT 1037

Query: 306  PGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQ 365
             G PG  G PGK GPP   GL+G PG  G+PG  G  G KG+ G PG PG    +G PG+
Sbjct: 1038 KGDPGPAGLPGKDGPP---GLRGFPGDRGLPGPVGALGLKGNEGPPGPPGP---AGSPGE 1091

Query: 366  QGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGV 425
            +GP G  GP G  G PG +G  GP G  G PG+ G  G  G  GL GP GLPG  G  G 
Sbjct: 1092 RGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGP 1151

Query: 426  VGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGP 485
             GE G KGE G  G++G  G++GE G  G  GP+G  G PG  G  G  G RG  G+ G 
Sbjct: 1152 PGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQ 1211

Query: 486  RGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGA 545
            +G  GPRG  G  G  GL G+ GPPG       + Q+                 R  SGA
Sbjct: 1212 KGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQM---------GPPGPPGPRGPSGA 1262

Query: 546  TGLPGRPGPP---GPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGP 602
             G  G  GPP   G PG  GE G PG+ G  GLPG  GPPG  G RG KG+ G  G  GP
Sbjct: 1263 PGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGP 1322

Query: 603  PG-------RGPNGLPGAIGLPGDPGPASY----------GRNGRDGERGPPGVAGIPGV 645
            PG        GP G PG +G PGDPGP             G  G DGE G  G  G  G 
Sbjct: 1323 PGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGE 1382

Query: 646  PGPPGPPGLPGFCEPASCTMQAGQR 670
            PGP GPPG  G   PA    + G++
Sbjct: 1383 PGPSGPPGKRGPPGPAGPEGRQGEK 1407



 Score =  528 bits (1360), Expect = e-150
 Identities = 318/700 (45%), Positives = 362/700 (51%), Gaps = 72/700 (10%)

Query: 7    DRGALGLLLLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGE 66
            DRG  GL        A   G  G +G PGP GPPG PG DG  GD G  GP G PG  G 
Sbjct: 629  DRGFDGL--------AGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGP 680

Query: 67   PGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGP------ 119
             G  G  G PG PG  G+TG DG PG  G+ G +GEPG PG +G PG +G+PGP      
Sbjct: 681  RGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGP 740

Query: 120  ---PGPPGTAGLPGELGRVGPVGDPGRRGPPGP---PGPPGPRGTIGFHDGDPLCPNACP 173
                GP G  GLPG  G  GP G PG+ GPPG     GPPGP+G IG+            
Sbjct: 741  PGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGY------------ 788

Query: 174  PGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGI 233
            PG  G  G  G+RG KG KGE GE G  G KG+ G +G+ GE+G  GP G  G  G  G 
Sbjct: 789  PGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGR 848

Query: 234  VGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGA---EGARGIPGLPGP 290
             G  G+ G  G  GE G  G+PG PG  G++GP G  G  G  GA   +G RG PG PGP
Sbjct: 849  GGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGP 908

Query: 291  KGD---TGLPGVDGRDGIPGMPGTKGE---PGKPGPPGDAGLQGLPGVPGIPGAKGVAGE 344
            +G    TG  G  G  GI G PG KG     G  GPPG+ G  G  G  G PG KG  G 
Sbjct: 909  RGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGP 968

Query: 345  KGSTGAPGKPGQMGNS---GKPGQQGPPGEVGPRGP---------QGLPGSRGELGPVGS 392
             G  G PG PGQ G +   GK G  GPPG VGP+GP         +G PG  G  G  G 
Sbjct: 969  PGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGL 1028

Query: 393  PGLPGKLGSLGSP---GLPGLPGPPGLPGMKGDRGV---VGEPGPKGEQGASGEEGEAGE 446
            PGL GK G+ G P   GLPG  GPPGL G  GDRG+   VG  G KG +G  G  G AG 
Sbjct: 1029 PGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGS 1088

Query: 447  RGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGV 506
             GE G  G  GP G  G PG  G  GP G +G PG +GP+GP G  G+QG  G  G  G 
Sbjct: 1089 PGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGP 1148

Query: 507  QGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGF 566
             GPPG       I +   +  +    E          G  G PG  G  G PGP G+ G 
Sbjct: 1149 VGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGL 1208

Query: 567  PGQMGIRGLPGIKGPPGALGLR------GPKGDLGEKGERGPPG----RGPNGLPGAIGL 616
             GQ G  G  G  GPPG +GL+      G KG+ G+ G+ GPPG    RGP+G PGA G 
Sbjct: 1209 FGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGP 1268

Query: 617  PGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
             G PG    G  G  GE+G PG AG PG+PG  GPPG  G
Sbjct: 1269 QGPPG--GIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKG 1306



 Score =  522 bits (1345), Expect = e-148
 Identities = 302/685 (44%), Positives = 348/685 (50%), Gaps = 76/685 (11%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 85
            GPPGE+GP G PG PG+PG DG  G  G +GPPG  G  G PG  G  G PG  G  G  
Sbjct: 739  GPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGAD 798

Query: 86   GPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGELGRVGPVGDPGRR 144
            G  G  G+ G KG+ G PG  G  G  G RG  GPPGP G  G  G  GR GP GDPG  
Sbjct: 799  GIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPL 858

Query: 145  GPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHK 204
            GPPG  G  G  G  G+           P G  G+PG PG  G KG +G  G+PG +G +
Sbjct: 859  GPPGEKGKLGVPGLPGYPGRQG------PKGSIGFPGFPGANGEKGGRGTPGKPGPRGQR 912

Query: 205  GEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGE---PGPQGLPGAPGD- 260
            G  G +GE G  G  G PG +G  G  G  G  GE+G  G  G    PGP+G PG PG  
Sbjct: 913  GPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKD 972

Query: 261  --------------QGQRGPPGEAG------PKGDRGAEGARGIPGLPGPKGDTGLPGVD 300
                          QG+ GPPG  G      P G+ G  G RG PG PGP G+ GLPG+ 
Sbjct: 973  GLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLA 1032

Query: 301  GRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNS 360
            G++G  G PG  G PGK GPPG   L+G PG  G+PG  G  G KG+ G PG PG    +
Sbjct: 1033 GKEGTKGDPGPAGLPGKDGPPG---LRGFPGDRGLPGPVGALGLKGNEGPPGPPGP---A 1086

Query: 361  GKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMK 420
            G PG++GP G  GP G  G PG +G  GP G  G PG+ G  G  G  GL GP GLPG  
Sbjct: 1087 GSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPA 1146

Query: 421  GDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLP 480
            G  G  GE G KGE G  G++G  G++GE G  G  GP+G  G PG  G  G  G RG  
Sbjct: 1147 GPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQ 1206

Query: 481  GVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKR 540
            G+ G +G  GPRG  G  G  GL G+ GPPG                             
Sbjct: 1207 GLFGQKGDEGPRGFPGPPGPVGLQGLPGPPG----------------------------- 1237

Query: 541  PDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKG-- 598
             + G TG  G+ GPPGPPGP G +G PG  G +G PG  G PGA+G +G  G+ GE G  
Sbjct: 1238 -EKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLP 1296

Query: 599  -ERGPPG----RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPG 653
             E GPPG    RG  G  G  G  G PGP   G  G DG +G PG  G PG PGPPG PG
Sbjct: 1297 GEGGPPGPKGERGEKGESGPSGAAGPPGPK--GPPGDDGPKGSPGPVGFPGDPGPPGEPG 1354

Query: 654  LPGFCEPASCTMQAGQRAFNKGPDP 678
              G   P       G+      P P
Sbjct: 1355 PAGQDGPPGDKGDDGEPGQTGSPGP 1379



 Score =  520 bits (1339), Expect = e-147
 Identities = 315/722 (43%), Positives = 361/722 (50%), Gaps = 132/722 (18%)

Query: 31   QGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLTGPDGS 90
            +GPPGP GP G+PG         P G  GP G  G+PG+ G PG+PG PGADGL GP G+
Sbjct: 468  EGPPGPEGPAGLPG---------PPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGT 518

Query: 91   P----------GSIGSKG-----QKGEP------------GVPGSRGFPGRGIPGPPGPP 123
                       G  GSKG     Q+ +             G  G  G  GR  PGP GPP
Sbjct: 519  MLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGR--PGPVGPP 576

Query: 124  GTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPP----GRSGY 179
            G+ GL GE G VGP G  G +GPPGP G PG RG  G  DG    P    P    G  G 
Sbjct: 577  GSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAG-SDGARGMPGQTGPKGDRGFDGL 635

Query: 180  PGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGE------------VGAQGPPGAQGL 227
             GLPG +GH+G  G  G PG  G  GE GD GE+G             +G +GPPG  G 
Sbjct: 636  AGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGP 695

Query: 228  RGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGL 287
             G+TG+ G  G KG  G  GEPGP G  G PG QG  GP G  GP G++G  G  G+PG+
Sbjct: 696  PGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGM 755

Query: 288  PGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGS 347
            PG  G    PG  G++G PG  G +G PG  GP G  G +G+ G  GI G KG  GEKG 
Sbjct: 756  PGADGP---PGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGE 812

Query: 348  TGAPGKPGQMGNSGKPGQQGPP---GEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGS 404
             G PG  G MG  G  G+ GPP   GE GP GP+G  G  G+ GP+G PG  GKLG  G 
Sbjct: 813  DGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGL 872

Query: 405  PGLPGLPGP------PGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGP 458
            PG PG  GP      PG PG  G++G  G PG  G +G  G  G  GERG  G  G PGP
Sbjct: 873  PGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGP 932

Query: 459  KGS------AGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGV---QGEQGATGLPGVQGP 509
            KG+      AG PGE G  GP+G  G PG +GP GPPG  G+    G++G TG  G  GP
Sbjct: 933  KGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP 992

Query: 510  PGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQ 569
            PG                            +  +G TG  G  G PGPPGPPGE G PG 
Sbjct: 993  PG---------------------PPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGL 1031

Query: 570  MGIRGL---------------PGIKGPPGALGLRGPKGDLGEKGERGPPG---------- 604
             G  G                PG++G PG  GL GP G LG KG  GPPG          
Sbjct: 1032 AGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGE 1091

Query: 605  RGPNGLPGAIGLPGDPG----PASYGRNGRDGERGPPGVAGIP------GVPGPPGPPGL 654
            RGP G  G IG+PG PG    P   G  G  GE+GP G AG        G+PGP GP G 
Sbjct: 1092 RGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGP 1151

Query: 655  PG 656
            PG
Sbjct: 1152 PG 1153



 Score =  475 bits (1223), Expect = e-134
 Identities = 309/745 (41%), Positives = 358/745 (48%), Gaps = 144/745 (19%)

Query: 37   PGPPGVPGIDGIDG----------DRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLTG 86
            P PP   G D ++G          D     P   P  +     PG P    T   +G+ G
Sbjct: 389  PAPPPGEGADDLEGEFTEETIRNLDENYYDPYYDPTSSPSEIGPGMPANQDTI-YEGIGG 447

Query: 87   PDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGP---VGDPGR 143
            P G       KGQKGEP +      PG  I GPPGP G AGLPG  G +GP   VGDPG 
Sbjct: 448  PRGE------KGQKGEPAIIE----PGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGE 497

Query: 144  RGPPGPP------GPPGPRGTI--------GFHDGDPLCP-------------------- 169
            RGPPG P      G PGP GT+        G  D     P                    
Sbjct: 498  RGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLAL 557

Query: 170  --NACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGL 227
               A P G +G PG  G  G  G KGE G+ G QG +G +G  G  G+ G +G  G+ G 
Sbjct: 558  RGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGA 617

Query: 228  RGITGIVGDKGEKGARGL---------DGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGA 278
            RG+ G  G KG++G  GL          G+PGP G PG PGD G+RG  GE GP+G  G 
Sbjct: 618  RGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGE 677

Query: 279  EGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGA 338
             G RG+ G  GP G  G PGV G DG PG  G  G  G+PGPPG  G  G  G+PG  GA
Sbjct: 678  PGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGA 737

Query: 339  KGVAGEKGSTGAPGKPGQMGNS---GKPGQQGPPGE------VGPRGPQGLPGSRGELGP 389
             G  GEKG  G PG PG  G     G PG++GPPGE       GP+GP G PG RG  G 
Sbjct: 738  IGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGA 797

Query: 390  VGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEA----- 444
             G  GL G  G  G  G PG  G  G+   KGDRG +G PGP+GE G  G +G       
Sbjct: 798  DGIRGLKGTKGEKGEDGFPGFKGDMGI---KGDRGEIGPPGPRGEDGPEGPKGRGGPNGD 854

Query: 445  -------GERGELGDIGLP------GPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGP 491
                   GE+G+LG  GLP      GPKGS G PG PG  G +G RG PG  GPRG  GP
Sbjct: 855  PGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGP 914

Query: 492  RGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGR 551
             G +GE+G  G+ G  GP G +  D                      +R  +G  G  G 
Sbjct: 915  TGPRGERGPRGITGKPGPKGNSGGD---------------GPAGPPGERGPNGPQGPTGF 959

Query: 552  PGPPGPPGPPGENGFPGQMGIRGLPGIK------GPPGALGLRGPKGDLGEKGERGPPGR 605
            PGP GPPGPPG++G PG  G RG  G +      GPPG +G +GP G+ G  GERG P  
Sbjct: 960  PGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHP-- 1017

Query: 606  GPNGLPGAIGLP---------GDPGPASY-GRNGRDGERGPPGVAGIP------------ 643
            GP G PG  GLP         GDPGPA   G++G  G RG PG  G+P            
Sbjct: 1018 GPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNE 1077

Query: 644  GVPGPPGPPGLPGFCEPASCTMQAG 668
            G PGPPGP G PG   PA      G
Sbjct: 1078 GPPGPPGPAGSPGERGPAGAAGPIG 1102



 Score =  297 bits (761), Expect = 2e-80
 Identities = 174/363 (47%), Positives = 195/363 (53%), Gaps = 40/363 (11%)

Query: 26   GPPGEQGPPG------PPGPPGVPGIDGIDGDRGPKGPP---GPPGPAGEPGKPGAPGKP 76
            GPPGE+G  G      PPGPPG  G  G  G  GP+GPP   G PG  GE G+PG  G+P
Sbjct: 1234 GPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEP 1293

Query: 77   GTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----RGIPGP---PGPPGTAGLP 129
            G PG  G  GP G  G  G  G  G  G PG +G PG    +G PGP   PG PG  G P
Sbjct: 1294 GLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEP 1353

Query: 130  GELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHK 189
            G  G+ GP GD G  G PG  G PGP G  G        P+  PPG+ G PG  G  G +
Sbjct: 1354 GPAGQDGPPGDKGDDGEPGQTGSPGPTGEPG--------PSG-PPGKRGPPGPAGPEGRQ 1404

Query: 190  GAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEP 249
            G KG  GE G +G  G+    G +G  GA G PG  GLRGI G VG++G  G+ G DG P
Sbjct: 1405 GEKGAKGEAGLEGPPGK---TGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPP 1461

Query: 250  GPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMP 309
            GP G PG PG +G  GP GE   KG  G  G  G PG  G KGD GLPG  G        
Sbjct: 1462 GPMGPPGLPGLKGDSGPKGE---KGHPGLIGLIGPPGEQGEKGDRGLPGPQGSS------ 1512

Query: 310  GTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPP 369
            G KGE G  GP G  G  G PG+PG PG KG    KGS+G  G  G+ G+ G PG  GPP
Sbjct: 1513 GPKGEQGITGPSGPIGPPGPPGLPGPPGPKGA---KGSSGPTGPKGEAGHPGPPGPPGPP 1569

Query: 370  GEV 372
            GEV
Sbjct: 1570 GEV 1572



 Score =  248 bits (634), Expect = 1e-65
 Identities = 146/313 (46%), Positives = 160/313 (51%), Gaps = 29/313 (9%)

Query: 22   AAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPP---GPAGEPGKPGAPGKPGT 78
            A + G PGE GPPGP G  G  G  G  G  GP GP GPP   GP G PG  G PG PG 
Sbjct: 1290 AGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGP 1349

Query: 79   PGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGELGRVGP 137
            PG  G  G DG PG  G  G+ G+ G PG  G PG  G PG  GPPG AG  G  G  G 
Sbjct: 1350 PGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGA 1409

Query: 138  VGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGE 197
             G+ G  GPPG  GP GP+G  G    D L     P G  G PG PG  G  G  G  G 
Sbjct: 1410 KGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGL 1469

Query: 198  PGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGA 257
            PG +G  G +G++G  G +G  GPPG Q            GEKG RGL   PGPQG  G 
Sbjct: 1470 PGLKGDSGPKGEKGHPGLIGLIGPPGEQ------------GEKGDRGL---PGPQGSSGP 1514

Query: 258  PGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGK 317
             G+QG  GP G  GP G  G      +PG PGPKG  G  G  G  G  G P   G PG 
Sbjct: 1515 KGEQGITGPSGPIGPPGPPG------LPGPPGPKGAKGSSGPTGPKGEAGHP---GPPGP 1565

Query: 318  PGPPGDAGLQGLP 330
            PGPPG+  +Q LP
Sbjct: 1566 PGPPGEV-IQPLP 1577



 Score =  223 bits (567), Expect = 6e-58
 Identities = 153/375 (40%), Positives = 174/375 (46%), Gaps = 56/375 (14%)

Query: 333 PGIPGAK-----GVAGEKGSTGAPGKPGQMGNSGKPGQ--QGPPGEVGPRGPQGLPGSRG 385
           PG+P  +     G+ G +G  G  G+P  +    +PG   +GPPG   P GP GLPG  G
Sbjct: 432 PGMPANQDTIYEGIGGPRGEKGQKGEPAII----EPGMLIEGPPG---PEGPAGLPGPPG 484

Query: 386 ELGPVGSPGLPGKLGSLGSPGLPG---LPGPPG----LPGMKGDRGVVGEPGPKG----- 433
            +GP G  G PG+ G  G PGLPG   LPGPPG    LP   G  G  G  GP       
Sbjct: 485 TMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQES 544

Query: 434 ------EQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRG 487
                 +Q      G AG  G  G  G  GP GS G  GEPG  GP+G RG+ G  GP G
Sbjct: 545 QAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAG 604

Query: 488 PPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATG 547
            PG RG  G  GA G+PG  GP G    D                   A L   + G  G
Sbjct: 605 KPGRRGRAGSDGARGMPGQTGPKGDRGFDG-----------------LAGLPG-EKGHRG 646

Query: 548 LPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR-G 606
            PG  GPPGPPG  GE G  G++G RGLPG  GP G LG +GP G  G  G  G  G+ G
Sbjct: 647 DPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPG 706

Query: 607 PNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGP---PGPPGLPGFCEPASC 663
           P G  G  G PG PG    G  G  G  GP G  G PG  GP   PG PG+PG   P   
Sbjct: 707 PKGNVGPQGEPGPPG--QQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGH 764

Query: 664 TMQAGQRAFNKGPDP 678
             + G      G  P
Sbjct: 765 PGKEGPPGEKGGQGP 779



 Score = 82.4 bits (202), Expect = 1e-15
 Identities = 47/110 (42%), Positives = 53/110 (48%), Gaps = 26/110 (23%)

Query: 15   LLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPG 74
            L+GL     ++G  G++G PGP G  G  G  GI G  GP GPPGPPG  G P       
Sbjct: 1487 LIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPP------- 1539

Query: 75   KPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPG 124
                       GP G+ GS G  G KGE G PG         PGPPGPPG
Sbjct: 1540 -----------GPKGAKGSSGPTGPKGEAGHPGP--------PGPPGPPG 1570


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score =  530 bits (1364), Expect = e-150
 Identities = 339/794 (42%), Positives = 391/794 (49%), Gaps = 157/794 (19%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGAD--- 82
            GPPG +G  G PGPPG+PG+ GI G RGP+GPPGP G  G PG PGA G+ G PG     
Sbjct: 625  GPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGK 684

Query: 83   ---------GLTGPDGSPGSIGSKGQKGEPGV---------------PGSRGFPGR-GIP 117
                     GL G  G+PG  G KG KG PG                PG++G+PGR G+P
Sbjct: 685  AHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLP 744

Query: 118  GPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRS 177
            GP G PG  G  G +G  G  G PG  G  G PG PG RG +G      +     PPG  
Sbjct: 745  GPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLD 804

Query: 178  GYP------------------------GLPGMRGHKGAKGEIGEPGRQGHKGEE------ 207
            G P                        G PG +G KG  G +GEPG +G KGE+      
Sbjct: 805  GNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVS 864

Query: 208  GDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLP------------ 255
            GD G  G+ G+QG PG  G RG  G +G  G+KG+ G  G PGP+G P            
Sbjct: 865  GDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPE 924

Query: 256  ---GAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTK 312
               G PG +G  GP G+ GP+GD G  G  G PGL G  G  G PG  G DG+ G PG  
Sbjct: 925  GMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDP 984

Query: 313  GEPGKPGPPGDAGLQGLPGVPGIPGAK---------GVAGEKGSTGAPGKPGQMGNSGKP 363
            G PG  G  G  G  GL G PGI G K         GV G KGS G PG PG MG  G+P
Sbjct: 985  GRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEP 1044

Query: 364  GQQGPPGEVGP---------RGPQGLPGSRGEL---------GPVGSPGLP------GKL 399
            G QGPPG  GP         RGP+G  G  GE          GP G PG P      G+ 
Sbjct: 1045 GPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGER 1104

Query: 400  GSLGSPGLPGLPGP---------PGLPGMKGDRGVVGEP---GPKGEQGASGE---EGEA 444
            G LGS G PG+PGP         PG PG +G +G +G P   GPKG  GA GE    GEA
Sbjct: 1105 GHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEA 1164

Query: 445  GERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLP 504
            G +G+LG +G PG +G  G  GEPGL G  G  G  G++G RG PGP G  GE+G  GL 
Sbjct: 1165 GMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLM 1224

Query: 505  GVQGPPG-------RAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGP 557
            G  GPPG       R P  +  KQ      +       A   +   G  G+PG PGPPG 
Sbjct: 1225 GEDGPPGPPGVTGVRGPEGKSGKQ----GEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGT 1280

Query: 558  PGPPGE------NGFPGQMGIRGLPGI------KGPPGALGLRGPKGDLGEKGE----RG 601
            PGP G        G PG+MG +G PG+      KG  G LG  GPKG+ GE+GE     G
Sbjct: 1281 PGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEG 1340

Query: 602  PPG----RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGP---PGPPGL 654
            PPG    RGP G  G  G PGDPG    G+ G  G RG PG  G PG PGP   PGP G 
Sbjct: 1341 PPGPPGDRGPVGDRGDRGEPGDPGYP--GQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGS 1398

Query: 655  PGFCEPASCTMQAG 668
             G   P     +AG
Sbjct: 1399 KGAEGPKGKQGKAG 1412



 Score =  512 bits (1319), Expect = e-145
 Identities = 314/725 (43%), Positives = 370/725 (51%), Gaps = 106/725 (14%)

Query: 24   QRGPPGEQGPPGP---PGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPG 80
            +RGPPG  G PG    PGPPGVPG+ G  G  GP G PGP G  G  G  G PG  G  G
Sbjct: 797  ERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKG 856

Query: 81   ADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-------RGIPGPPGPPGTAGLPGELG 133
              G+ G  G PG  G KG +G PG PG+RG PG       +G  G PGPPG  G PG++G
Sbjct: 857  EQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIG 916

Query: 134  RVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKG 193
              G  G  G +G PG  G PGPRG +G  +GD         G  G PG PG+ G  G KG
Sbjct: 917  PPGDNGPEGMKGKPGARGLPGPRGQLG-PEGDE--------GPMGPPGAPGLEGQPGRKG 967

Query: 194  EIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQG 253
              G PG  G KGE GD G  G VG QG  G  GL G  GIVG+KG++G  G  G PGP+G
Sbjct: 968  FPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKG 1027

Query: 254  L---PGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPG 310
                PG PG  G  G PG  GP G RG  G RG  G  GP+G  G  G  G  G+ G PG
Sbjct: 1028 SMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPG 1087

Query: 311  TKGEPGKPGPPGDAGLQG---LPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQG 367
             +G PG+PG  G AG +G     G PGIPG  G  G KG  G PG  G  G  G PG+ G
Sbjct: 1088 PQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMG 1147

Query: 368  PPGEVGPRGPQGLPGS---RGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRG 424
            P G  G  G  GLPG    +G+LGP+G+PG  G +G  G PGL G  GP G  G+KGDR 
Sbjct: 1148 PKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDR- 1206

Query: 425  VVGEPGPKGEQGASGEEGEAGERGELGD---IGLPGPKGSAGNPGEPGLRGPEGSR---- 477
              G+PGP GE G  G+EG  GE G  G     G+ GP+G +G  GE G  G +G++    
Sbjct: 1207 --GDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQG 1264

Query: 478  -----GLPGVEGPRGPPGPRGVQGEQGATGLP---GVQGPPGRAPTDQHIKQVCMRVIQE 529
                 G+PG  GP G PGP+G +G  G TG P   G QG PG A  D H      + I  
Sbjct: 1265 QLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGH------KGIVG 1318

Query: 530  HFAEMAASLKRPDSGATG-LPGRPGPPGPPGP---------PGENGFPGQMGIRGL---- 575
                     ++ + G  G   G PGPPG  GP         PG+ G+PGQ G++GL    
Sbjct: 1319 PLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKP 1378

Query: 576  --------PGIKGPPGALGLRGPKGDLGEKGERGPPGR----------GPNGLPGAIGLP 617
                    PG +G PG  G +G +G  G++G+ G PGR          GP G+ G  GL 
Sbjct: 1379 GQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLE 1438

Query: 618  GDPGP----------ASYGRNGRDGERGP---------PGVAGIPGVPGPP---GPPGLP 655
            G  GP             G  G DG+ GP         PGVAG+PG  GPP   G  GLP
Sbjct: 1439 GIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLP 1498

Query: 656  GFCEP 660
            G   P
Sbjct: 1499 GQLGP 1503



 Score =  508 bits (1307), Expect = e-144
 Identities = 299/667 (44%), Positives = 349/667 (52%), Gaps = 62/667 (9%)

Query: 25   RGPPGEQGPPGPPGPPGV---------PGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGK 75
            +G PG+ G PGP G  G          PGI G  GDRG  GPPG PGP G  G PG PG 
Sbjct: 978  KGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGG 1037

Query: 76   PGTPGADGLTGPDGS---PGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGE 131
             GTPG  G  GP GS   PG  G+KG++G  G  G  G  G RG+ GPPGP G  G PG+
Sbjct: 1038 MGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQ 1097

Query: 132  LGRVG---------------PVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGR 176
             G  G               P G PG +G PG PGP GP+G IG      + P   PPG 
Sbjct: 1098 QGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIG--PPGEMGPKG-PPGA 1154

Query: 177  SGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGD 236
             G PGLPG  G KG  G +G PG QG  G+ G+ G  G+ G  GP G +G RG  G  G+
Sbjct: 1155 VGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGE 1214

Query: 237  KGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGL 296
             GEKG  GL GE GP   PG PG  G RGP G++G +G++G  GA+G  G  G  G+ G+
Sbjct: 1215 HGEKGQEGLMGEDGP---PGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGV 1271

Query: 297  PGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQ 356
            PG  G  G PG  G++G  G  G PG  G QG PG+ G  G KG+ G  G  G  G+ G+
Sbjct: 1272 PGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGE 1331

Query: 357  MGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGL 416
             G  GK   +GPPG  G RGP G  G RGE G  G PG  G  G  G PG  G PG PG 
Sbjct: 1332 QGEDGKA--EGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGP 1389

Query: 417  PGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEG- 475
             G  G +G  G  GPKG+QG +G  G    RG  G  GLPGP+G  G  G  G+ GP+G 
Sbjct: 1390 RGWPGPKGSKGAEGPKGKQGKAGAPGR---RGVQGLQGLPGPRGVVGRQGLEGIAGPDGL 1446

Query: 476  --------SRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVI 527
                     +G  G +G  GP GP G +G  G  GLPG QGPPG             +  
Sbjct: 1447 PGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPG------------FKGE 1494

Query: 528  QEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGL 587
                 ++    KR   G TGLPG  G PG  G PG++G  G  G+ GL G KGPPG +G 
Sbjct: 1495 SGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGF 1554

Query: 588  RGPKGDLGEKGERGPPGR-GPNGLPGAIGLPGDPGP-ASYGRNGRDGERGPPGVAGIPGV 645
            +G +G  G  G  G  G  GP G+ G  GLPG  G   S G  G  G RGPPG  G PG 
Sbjct: 1555 KGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGP 1614

Query: 646  PGPPGPP 652
            PGPPG P
Sbjct: 1615 PGPPGGP 1621



 Score =  463 bits (1191), Expect = e-130
 Identities = 292/662 (44%), Positives = 333/662 (50%), Gaps = 80/662 (12%)

Query: 64   AGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPG-- 121
            AG    P   G PG  G  GL GP G PG  G  G +G  G PG  G P  G+PGPPG  
Sbjct: 615  AGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNP--GLPGPPGAK 672

Query: 122  --------PPGTA--------GLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGD 165
                     PG A        GLPG  G  GP G  G +G PGP G PG +G  G  +G 
Sbjct: 673  GQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPG-PEGS 731

Query: 166  PLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQ 225
            P       PGR G PG  G  G KG++G IG PG  G  G +G++      G  G PG +
Sbjct: 732  PGAKGY--PGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGER------GLPGVPGKR 783

Query: 226  GLRGITGIVGDKGEKGARGLDGEPGPQGLPGAP------GDQGQRGPPGEAGPKGDRGAE 279
            G  G+ G  G  GE+G  GLDG PG  GLPG P      GD G  GP G  GPKG +G  
Sbjct: 784  GKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLM 843

Query: 280  GARGIPGLPGPKGDTGLPGVD---------GRDGIPGMPGTKGEPGKPGPPGDAGLQGLP 330
            G+ G PGL G KG+ G+PGV          G  G+PG PG +G+PG  G  GD G  G P
Sbjct: 844  GSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFP 903

Query: 331  GVP---GIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGEL 387
            G P   G PG  G  G+ G  G  GKPG  G  G  GQ GP G+ GP GP G PG  G+ 
Sbjct: 904  GPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQP 963

Query: 388  GPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGER 447
            G  G PG PG  G  G PG PG PGP G  G  G  G+VGEPG  GE+G  G  G  G  
Sbjct: 964  GRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVP 1023

Query: 448  GELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGV------EGPRGPPGPRGVQGEQGAT 501
            G  G +G PG  G  G PGEPG +GP GSRG PG+       GPRGP GP G QG +G  
Sbjct: 1024 GPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLK 1083

Query: 502  GLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPP 561
            G PG QG PGR P  Q +      +    F  +      P  G  GLPG PGP GP GP 
Sbjct: 1084 GPPGPQGRPGR-PGQQGVAGERGHLGSRGFPGIPGPSGPP--GTKGLPGEPGPQGPQGPI 1140

Query: 562  GENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEK---------GERGPPG----RGPN 608
            G    PG+MG +G PG  G PG  G  G KGDLG           G+RG PG     GP 
Sbjct: 1141 GP---PGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPM 1197

Query: 609  GLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAG 668
            G  G  G  GDPGP        DGE G  G  G+ G  GPPGPPG+ G   P   + + G
Sbjct: 1198 GPDGLKGDRGDPGP--------DGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQG 1249

Query: 669  QR 670
            ++
Sbjct: 1250 EK 1251



 Score =  428 bits (1101), Expect = e-120
 Identities = 271/637 (42%), Positives = 325/637 (51%), Gaps = 77/637 (12%)

Query: 7    DRGALGLL-LLGLCLCAAQRGPPGEQGPPGPPGP------PGVPGIDGIDGDRGPKGPPG 59
            ++G +G + L+G      ++G  G  GPPG PGP      PG+PG  G  G+ GP+GPPG
Sbjct: 992  EQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPG 1051

Query: 60   ---PPGPAGEPGK------PGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRG 110
               PPG  G  G+       G  G+ G+ G  G  GP G PG  G +G  GE G  GSRG
Sbjct: 1052 SRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRG 1111

Query: 111  FPGRGIPGPPGPPGTAGLPGE---LGRVGPVGDPGRRGPPGPPGP---PGPRGTIGFHDG 164
            FPG  IPGP GPPGT GLPGE    G  GP+G PG  GP GPPG    PG  G  G   G
Sbjct: 1112 FPG--IPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMK-G 1168

Query: 165  DPLCPNACPP-----GRSGYPGLPG---MRGHKGAKGEIGEPGRQGHKGEEGDQGELGEV 216
            D L P   P      G+ G PGL G     G  G KG+ G+PG  G  GE+G +G +GE 
Sbjct: 1169 D-LGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGED 1227

Query: 217  GAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDR 276
            G  GPPG  G+RG  G  G +GEKG  G  G  G QG  G  G  G  GPPG  GPKG R
Sbjct: 1228 GPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSR 1287

Query: 277  GAEGARGIPGLPGPKGDTGLPGVDGRDGI------PGMPGTKGEPGK-------PGPPGD 323
            G+ G  G PG  G +G+ GL G DG  GI      PG  G KGE G+       PGPPGD
Sbjct: 1288 GSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGD 1347

Query: 324  AGL------QGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGP 377
             G       +G PG PG PG +GV G +G  G  G+PG  G  G PG +G  G  GP+G 
Sbjct: 1348 RGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGK 1407

Query: 378  QGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPG------MKGDRGVVGEPGP 431
            QG  G+ G  G  G  GLPG  G +G  GL G+ GP GLPG       +G++G  G+PGP
Sbjct: 1408 QGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGP 1467

Query: 432  KGEQGASGEEGEAG------------ERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGL 479
             G  G  G  G AG            E G  G +G PG +G+ G  G PG +G  GS+G 
Sbjct: 1468 MGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQ 1527

Query: 480  PGVEGPRGPPG------PRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAE 533
            PG  G  G PG      P+G  G+ G  G+ G +GPPG    +  +  + +         
Sbjct: 1528 PGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGP 1587

Query: 534  MAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQM 570
                  R D G  G  G PGP G PGPPG  G P Q+
Sbjct: 1588 KGDKGSRGDWGLQGPRGPPGPRGRPGPPGPPGGPIQL 1624



 Score =  385 bits (989), Expect = e-107
 Identities = 261/684 (38%), Positives = 318/684 (46%), Gaps = 100/684 (14%)

Query: 27   PPGEQGPP--GPPGPPGVPGIDGI-DGDRGPKGPPGPP-----GPAGEPGKPGAPGKPG- 77
            PP    PP  G   P   P +        G K P G       GP   P KP  P +PG 
Sbjct: 503  PPATMVPPTSGTSTPRTAPAVPTPGSAPTGSKKPIGSEASKKAGPKSSPRKP-VPLRPGK 561

Query: 78   ----TPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELG 133
                 P +D  T P  SP     + Q  +   P     P + +   P P  +      L 
Sbjct: 562  AARDVPLSDLTTRP--SP----RQPQPSQQTTPALVLAPAQFLSSSPRPTSSGYSIFHLA 615

Query: 134  RVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKG 193
               P   P   GPPGP G  G  G               PPG  G PG+PG RG +G  G
Sbjct: 616  GSTPF--PLLMGPPGPKGDCGLPG---------------PPGLPGLPGIPGARGPRGPPG 658

Query: 194  EIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQG 253
              G PG  G  G +G +G+ G    +   GA+G  G+ G+ G+ G  G +G  G PGP G
Sbjct: 659  PYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAG 718

Query: 254  LPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKG 313
                PG+QGQ GP G  G KG  G +G  G  G PGPKG  G  G+ G   + G+PG+ G
Sbjct: 719  ---HPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPG---LFGLPGSDG 772

Query: 314  EPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVG 373
            E G PG PG  G  G+PG PG      V GE+G  G  G PG++G  G PG  G  G++G
Sbjct: 773  ERGLPGVPGKRGKMGMPGFPG------VFGERGPPGLDGNPGELGLPGPPGVPGLIGDLG 826

Query: 374  PRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKG 433
              GP G PG +G  G +GS G PG  G  G  G+PG+ G PG  G KG +G+ G PG +G
Sbjct: 827  VLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARG 886

Query: 434  EQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEG---PRGPPG 490
            + G  G+    G++G +G  G PGP+G  G+ G PG  GPEG +G PG  G   PRG  G
Sbjct: 887  KPGPLGK---VGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLG 943

Query: 491  PRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPG 550
            P G +G  G  G PG++G PGR                           RP  G  G+ G
Sbjct: 944  PEGDEGPMGPPGAPGLEGQPGRKGFPG----------------------RP--GLDGVKG 979

Query: 551  RPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGL 610
             PG PG PGP GE GF G +G+ G PGI G  G  G+ GP G  G KG  G PG     +
Sbjct: 980  EPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPG-----M 1034

Query: 611  PGAIGLPGDPGPAS----------YGRNGRDGERGPPGVAG------IPGVPGPPGPPGL 654
            PG +G PG+PGP             G  GR G RGP G AG      + G PGP G PG 
Sbjct: 1035 PGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGR 1094

Query: 655  PGFCEPASCTMQAGQRAFNKGPDP 678
            PG    A      G R F   P P
Sbjct: 1095 PGQQGVAGERGHLGSRGFPGIPGP 1118



 Score = 90.1 bits (222), Expect = 6e-18
 Identities = 111/376 (29%), Positives = 135/376 (35%), Gaps = 97/376 (25%)

Query: 306 PGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQ 365
           PGMP       +P PP    L         P       E   T    KP     S     
Sbjct: 430 PGMP-------RPPPPSTRPLPPTTSSSKKPIPTLARTEAKITSHASKPASARTST---H 479

Query: 366 QGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGV 425
           + PP       P   PGS     P  +  +P   G+      P +P P   P        
Sbjct: 480 KPPPFTALSSSPAPTPGSTRSTRPPATM-VPPTSGTSTPRTAPAVPTPGSAP-------- 530

Query: 426 VGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGP 485
            G   P G         EA ++         GPK S   P    LR  + +R +P +   
Sbjct: 531 TGSKKPIGS--------EASKKA--------GPKSSPRKPVP--LRPGKAARDVP-LSDL 571

Query: 486 RGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGA 545
              P PR  Q  Q  T  P +   P                     A+  +S  RP S  
Sbjct: 572 TTRPSPRQPQPSQQTT--PALVLAP---------------------AQFLSSSPRPTSSG 608

Query: 546 ------TGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPK-------- 591
                  G    P   GPPGP G+ G PG  G+ GLPGI   PGA   RGP+        
Sbjct: 609 YSIFHLAGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGI---PGA---RGPRGPPGPYGN 662

Query: 592 ----GDLGEKGERGPPGRGP----NGLPGAIGLP---GDPGPASYGRNGRDGERGPPGVA 640
               G  G KG++G PG  P    +G  G +GLP   G+PGP      GR G +G PG A
Sbjct: 663 PGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPP-----GRKGHKGYPGPA 717

Query: 641 GIPGVPGPPGPPGLPG 656
           G PG  G PGP G PG
Sbjct: 718 GHPGEQGQPGPEGSPG 733


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score =  526 bits (1355), Expect = e-149
 Identities = 321/769 (41%), Positives = 375/769 (48%), Gaps = 147/769 (19%)

Query: 17   GLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKP 76
            GL      +G  GE+GP GPPGPPG  G+ G DG+ GP+G PG  GP G  G  G PG P
Sbjct: 616  GLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAP 675

Query: 77   GTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGELGRV 135
            G P   G+ G DG PG  G+ G +GEPG PG +G PG +G+PGP GP G  G  G  G+ 
Sbjct: 676  GQP---GMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP 732

Query: 136  GPVGDPGRRGPPGPP------------GPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLP 183
            G  G PG  GPPG P            GPPGP+G IG+           P G  G  G+ 
Sbjct: 733  GLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPG---------PRGVKGADGVR 783

Query: 184  GMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGAR 243
            G++G KG KGE G PG +G  G +GD+GE+G++G +G  G +G +G  G  GD G  G  
Sbjct: 784  GLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQA 843

Query: 244  GLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGD------TGLP 297
            G  G+ G  GLPG PG QG +G  G  G  G  G +GARG+ G PGP+G        G  
Sbjct: 844  GEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSR 903

Query: 298  GVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQM 357
            G  G  G PG  GT G  G PGPPG+ G QG  G  G PG KG  G  G  G PG PGQ 
Sbjct: 904  GARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQR 963

Query: 358  GNSGKPGQQGPPGE---VGPRGP---------------------QGLPGSRGELGPVGSP 393
            G +G  G+ GPPG    VGP+GP                     QGLPG+ G+ G  G P
Sbjct: 964  GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP 1023

Query: 394  GLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDI 453
            G  G  G  G  GL G PG  GLPG +G  G+ G  GP+G  G  G  GE G  G  G I
Sbjct: 1024 GPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPI 1083

Query: 454  GLP------GPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGP---------------- 491
            GLP      GP G AG  G PG +GP+G  G  GV+GP G PGP                
Sbjct: 1084 GLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEI 1143

Query: 492  --------RGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDS 543
                    +G +GE G  G PG+QGP G         +   R  Q  F +      + D 
Sbjct: 1144 GEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQ------KGDE 1197

Query: 544  GATGLPGRPGP------PGPPGPPGENGFPGQMGIRGLPGIK------------------ 579
            GA G PG PGP      PGPPG  GENG  G MG  G PG +                  
Sbjct: 1198 GARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV 1257

Query: 580  ------------------GPPGALGLRGPKGDLGEKGERGPPGR-------------GPN 608
                              GPPG  G+ GPKG+ GEKGE GPPG              GP 
Sbjct: 1258 GSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPK 1317

Query: 609  GLPGAIGLPGDPG-PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
            G PG +G PGDPG P   G  G+DG  G  G  G PG PGPPGP G  G
Sbjct: 1318 GNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAG 1366



 Score =  526 bits (1354), Expect = e-149
 Identities = 309/691 (44%), Positives = 356/691 (51%), Gaps = 69/691 (9%)

Query: 23   AQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGAD 82
            A RGPPG  G  G PGP G PG  G  G+ G  GP GP G  G PG  G PGK G PGAD
Sbjct: 538  ALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD 597

Query: 83   GLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGELGRVGPVGDP 141
            G  G  G PG+ G +G  G PG+PG +G  G RG  GPPGPPG  G+ GE G +GP G P
Sbjct: 598  GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLP 657

Query: 142  GRRGP---------PGPP---------GPPGPRGTIGFHDGDPLCP----NACP---PGR 176
            G  GP         PG P         GPPGP+G +G   G+P  P    N  P   PG 
Sbjct: 658  GEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMG-PQGEPGPPGQQGNPGPQGLPGP 716

Query: 177  SGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGD 236
             G  G PG +G +G  G  G PG  G  G  G +G+ GE GA GPPG QG  G  G  G 
Sbjct: 717  QGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGV 776

Query: 237  KGEKGARGL---DGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGD 293
            KG  G RGL    GE G  G PG  GD G +G  GE G  G RG +G  G  G  GP GD
Sbjct: 777  KGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGD 836

Query: 294  TGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGK 353
             G  G  G  G  G+PG  G PG+ GP G  G  G PG  G  GA+GVAG+ G  G  G 
Sbjct: 837  PGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGP 896

Query: 354  PGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGP 413
             G  G+ G  G  G PG  G  G  G PG  GE GP G  G  G  G  G PG PG  G 
Sbjct: 897  TGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGL 956

Query: 414  PGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGP 473
            PG PG +G+ G  G+ GP G  G  G +G  GE G +G+ G PGP G  G  G PG  G 
Sbjct: 957  PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK 1016

Query: 474  EGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAE 533
            EG++G PG +G  G  GP G++G  G  GLPG QG PG    +           Q     
Sbjct: 1017 EGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP---------QGPPGP 1067

Query: 534  MAASLKRPDSGATG---LPGRPGPPGPPGPPGENGFPGQMGIR------------GLPGI 578
            + +  +R  +G  G   LPGRPGP GPPGP GE G PG+ G +            GLPG 
Sbjct: 1068 VGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGP 1127

Query: 579  KGPPGALGLRGPKGDLGE---------KGERGPPG----RGPNGLPGAIGLPGDPGPASY 625
             GP G+ G  G KG++GE         KGE GPPG    +GP G PG  G  G+PGP   
Sbjct: 1128 AGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPR-- 1185

Query: 626  GRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
            G+ G  G++G  G  G PG PGP G  GLPG
Sbjct: 1186 GQQGMFGQKGDEGARGFPGPPGPIGLQGLPG 1216



 Score =  516 bits (1330), Expect = e-146
 Identities = 320/739 (43%), Positives = 362/739 (48%), Gaps = 120/739 (16%)

Query: 26   GPPGEQGPPGPPGPPG---------VPGIDGIDGDRGPKGP---PGPPGPAGEPGKPGAP 73
            GP G  GP G PGP G         VPG+ G  G +GPKG    PG PG  GE G  G  
Sbjct: 826  GPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVA 885

Query: 74   GKPGTPGADGLTGPDGS---------PGSIGSKGQKGEPGVPGSRGFPGR-------GIP 117
            GKPG  G  G TGP GS         PG  G+ G  G PG PG RG  G        G  
Sbjct: 886  GKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPK 945

Query: 118  GPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGF--------HDGDPLCP 169
            GPPGPPG  GLPG  G+ G  G  G+ GPPGP G  GP+G  G         H G P   
Sbjct: 946  GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPP--- 1002

Query: 170  NACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRG 229
               PPG  G PG  G  G KG  G  G  G+ G  G  G  GE G  GAQG PG +G  G
Sbjct: 1003 --GPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEG 1060

Query: 230  ITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGP------PGEAGPKGDRGAEGARG 283
              G  G  G  G RG  G  GP GLPG PG QG  GP      PGE GP+G  G +G +G
Sbjct: 1061 PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQG 1120

Query: 284  IPGLPGPKGDTGLPGVDGRDGI---PGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGA-- 338
              GLPGP G  G PG DG  G    PG  G+KG+ G+ GPPG  GLQG  G PGI G   
Sbjct: 1121 PVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDG 1180

Query: 339  -------KGVAGEKGSTGA---------------PGKPGQMGNSGKPGQQGPPGEVGPRG 376
                   +G+ G+KG  GA               PG PG+ G +G  G  GPPG  GPRG
Sbjct: 1181 EPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRG 1240

Query: 377  PQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGM------KGDRGVVGEPG 430
            PQG  G+ G  GP GS G  G +G  G PG  G PGPPG  G+      +G++G  G PG
Sbjct: 1241 PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPG 1300

Query: 431  PKGEQGASGEEGEAGERGELGDIGLPGP------------------KGSAGNPGEPGLRG 472
              G  GA G  G+ G +G  G +G PG                   KG  G+PG+PG  G
Sbjct: 1301 AAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1360

Query: 473  PEGSRGLPGVEGPRGPPGPRGV---QGEQGATGLPGVQGPPGR-APTDQHIKQVCMRVIQ 528
            P G  G PG  G RGPPG  G    QGE+GA G  G +GPPG+  P              
Sbjct: 1361 PSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGP------QGPAG 1414

Query: 529  EHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLR 588
            +   E    +  P  G  GLPG  G  GPPGP G  G PG  G  G  G KG PG +GL 
Sbjct: 1415 KPGPEGLRGIPGP-VGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLI 1473

Query: 589  GPKGDLGEKGERGPPG-------RGPNGLP---GAIGLPGDPG-PASYGRNGRDGERGPP 637
            GP G+ GEKG+RG PG       +G  G+P   G +G PG PG P   G  G  G  GP 
Sbjct: 1474 GPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPA 1533

Query: 638  GVAGIPGVPGPPGPPGLPG 656
            G  G  G+PGPPG PG PG
Sbjct: 1534 GQKGDSGLPGPPGSPGPPG 1552



 Score =  505 bits (1300), Expect = e-143
 Identities = 298/694 (42%), Positives = 344/694 (49%), Gaps = 100/694 (14%)

Query: 31   QGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLTGPDGS 90
            +GPPGP GP G+          GP G  GP GP G+PG  G PG+PG PGADGL GP G+
Sbjct: 453  EGPPGPAGPAGI---------MGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGT 503

Query: 91   ----PGSIGSKGQKGEP--------------------GVPGSRGFPGRGIPGPPGPPGTA 126
                P   G  G KG                      G PG  G  GR  PGP G PG++
Sbjct: 504  MLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGR--PGPVGGPGSS 561

Query: 127  GLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGD--PLCPNA-CPPGRSGYPGLP 183
            G  GE G  GP G  G +GPPGP G PG RG  G   G   P  P A    G  G PGLP
Sbjct: 562  GAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLP 621

Query: 184  GMRGHKGAKGEIGEPGRQGHKGEEGDQGELGE------------VGAQGPPGAQGLRGIT 231
            G +GH+G +G  G PG  G  G  G+ GE+G             +G +G PGA G  G+ 
Sbjct: 622  GDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMA 681

Query: 232  GIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPK 291
            G+ G  G KG  G  GEPGP G  G PG QG  GP G  GP G++G +G  G+ GLPG  
Sbjct: 682  GVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD 741

Query: 292  GDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAP 351
            G  G PG +G+ G  G  G  G  G  G PG  G++G  GV G+ G+KG  GE G  G  
Sbjct: 742  GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK 801

Query: 352  GKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLP 411
            G  G  G+ G+ GQ GP GE GP GP+G  G  G+ GP G  G  GKLG  G PG PG  
Sbjct: 802  GDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQ 861

Query: 412  GP---------PGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSA 462
            GP         PG  G KG RGV G+PGP+G++G +G  G  G RG  G  G  G  G  
Sbjct: 862  GPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGD 921

Query: 463  GNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQ------GEQGATGLPGVQGPPGRAPTD 516
            G PG PG RGP+G +G  G  GP+GPPGP G        G++G TG  G  GPPG     
Sbjct: 922  GPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPG--- 978

Query: 517  QHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLP 576
                                   +  +G TG  G  G PGPPGPPGE G PG  G  G  
Sbjct: 979  ------------------GVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAK 1020

Query: 577  GIKGPPGALGLRGPKGDLGEKGERGPP----------GRGPNGLPGAIGLPGDPGPAS-- 624
            G  GP G  G  GP G  G  GERG P          G GP G PG +G PG+ G A   
Sbjct: 1021 GDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTA 1080

Query: 625  --YGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
               G  GR G +GPPG AG  G PG  GP G  G
Sbjct: 1081 GPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAG 1114



 Score =  484 bits (1245), Expect = e-136
 Identities = 281/617 (45%), Positives = 322/617 (52%), Gaps = 45/617 (7%)

Query: 24   QRGPPGEQGPPGPPGPPGVPGIDGIDGDRGP---KGPPGPPGPAGEPGKPGAPGKPGTPG 80
            QRG  G QG  GPPGP GV G  G  G+ GP   +G PGPPGP GE G PGA GK G  G
Sbjct: 962  QRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKG 1021

Query: 81   ADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGE---LGRVG 136
              G  G  G  G  G +G  GE G+PG++G PG +G  GP GPPG  G PGE    G  G
Sbjct: 1022 DPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAG 1081

Query: 137  PVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNAC-----PPGRSGYPGLPGMRGHKGA 191
            P+G PGR GP GPPGP G +G  G  +  P  P        P G  G  G  G  G  G 
Sbjct: 1082 PIGLPGRPGPQGPPGPAGEKGAPG--EKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGD 1139

Query: 192  KGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGP 251
            KGEIGEPG++G KG++G+ G  G  G QGP GA G+ G  G  G +G++G  G  G+ G 
Sbjct: 1140 KGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGA 1199

Query: 252  QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGT 311
            +G PG PG  G +G PG  G KG+ G  G  G PG PGP+G  G  G DG  G PG  G+
Sbjct: 1200 RGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGS 1259

Query: 312  KGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGE 371
             G  G+ G PG+AG  G PG  G+ G KG  GEKG  G PG  G  G  G PG  GP G 
Sbjct: 1260 VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1319

Query: 372  VGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGL---PGMKGDRGVVGE 428
             GP G  G PG  GE GP G  G+ G  G  G PG PG PGP G    PG  G RG  G 
Sbjct: 1320 PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGA 1379

Query: 429  PGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRG---PEGSRGLPGVEGP 485
             G +G QG  G +GEAG  G  G  G  GP+G AG PG  GLRG   P G +GLPG  G 
Sbjct: 1380 AGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQ 1439

Query: 486  RGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGA 545
             GPPGP       G  GLPG++G PG      H   + +        E          G+
Sbjct: 1440 DGPPGP------MGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGS 1493

Query: 546  TGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG- 604
             G  G  G PGP GP                   GPPG  GL GP+G  G KG  GP G 
Sbjct: 1494 PGAKGDGGIPGPAGP------------------LGPPGPPGLPGPQGPKGNKGSTGPAGQ 1535

Query: 605  RGPNGLPGAIGLPGDPG 621
            +G +GLPG  G PG PG
Sbjct: 1536 KGDSGLPGPPGSPGPPG 1552



 Score =  454 bits (1169), Expect = e-128
 Identities = 292/682 (42%), Positives = 339/682 (49%), Gaps = 113/682 (16%)

Query: 69   KPGAPGK----PGTPGADGLTGPD-GSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPP 123
            KP +P      PG P    +T       G+ G KGQKGEP V      PG  + GPPGP 
Sbjct: 404  KPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVE----PGMLVEGPPGPA 459

Query: 124  GTAGL---PGELGRVGPVGDPGRRGPPGPPGPPGPRGTIG----------FHDGD----- 165
            G AG+   PG  G  GP GDPG RGPPG PG PG  G  G           + GD     
Sbjct: 460  GPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGP 519

Query: 166  ------------------PLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEE 207
                               L     P G +G PG  G  G  GAKGE G+PG QG +G +
Sbjct: 520  TISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQ 579

Query: 208  GDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEP---------GPQGLPGAP 258
            G  G  G+ G +G PGA G RG+ G  G KG++G  GL G P         GPQG PG P
Sbjct: 580  GPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP 639

Query: 259  GDQGQRGPPGEAGPKGDRGAEGARGI---PGLPGPKGDTGLPGVDGRDGIPGMPGTKGEP 315
            GD G RG  GE GP+G  G  G RG+    G PG  G  G+ GVDG  G  G  G +GEP
Sbjct: 640  GDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEP 699

Query: 316  GKPGPPGDAGLQGLPGVP---GIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEV 372
            G PG  G+ G QGLPG     G PG KG  G+ G  G PG  G  G+ GK GQ G  G +
Sbjct: 700  GPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL 759

Query: 373  GPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPK 432
            GP GPQG  G  G  G  G+ G+ G  GS G  G  G PG  G  G+KGDRG VG+ GP+
Sbjct: 760  GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR 819

Query: 433  GEQGASGEE------------GEAGERGELGDIGLP------GPKGSAGNPGEPGLRGPE 474
            GE G  G +            G+AGE+G+LG  GLP      GPKGS G PG PG  G +
Sbjct: 820  GEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEK 879

Query: 475  GSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEM 534
            G+RG+ G  GPRG  GP G +G +GA G  G  GP G +  D                  
Sbjct: 880  GARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGD---------------GPP 924

Query: 535  AASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIK---GPPGALGLRGPK 591
                +R   G  G  G PGP GPPGPPG++G PG  G RG  G +   GPPG  G+ GP+
Sbjct: 925  GPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQ 984

Query: 592  ------GDLGEKGERGPPG-RGPNGLPGAI---GLPGDPGPASY-------GRNGRDGER 634
                  G +GE+G  GPPG  G  GLPGA    G  GDPGP          G  G  GER
Sbjct: 985  GPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGER 1044

Query: 635  GPPGVAGIPGVPGPPGPPGLPG 656
            G PG  G PG+ G  GP G PG
Sbjct: 1045 GLPGAQGAPGLKGGEGPQGPPG 1066



 Score =  386 bits (992), Expect = e-107
 Identities = 219/475 (46%), Positives = 244/475 (51%), Gaps = 44/475 (9%)

Query: 16   LGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGK 75
            +GL   A   G PGE G  G  G PG  G  G  G+ GP GPPG  GP G PG  G  G+
Sbjct: 1122 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGE 1181

Query: 76   PGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRV 135
            P         GP G  G  G KG +G            RG PGPPGP G  GLPG  G  
Sbjct: 1182 P---------GPRGQQGMFGQKGDEG-----------ARGFPGPPGPIGLQGLPGPPGEK 1221

Query: 136  GPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEI 195
            G  GD G  GPPGPPGP GP+G  G  DG        P G  G  G  G  G KG  GE 
Sbjct: 1222 GENGDVGPMGPPGPPGPRGPQGPNG-ADG--------PQGPPGSVGSVGGVGEKGEPGEA 1272

Query: 196  GEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLP 255
            G PG  G  G  G +GE GE G  GPPGA G  G  G  GD G K      G PGP G P
Sbjct: 1273 GNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPK------GNPGPVGFP 1326

Query: 256  GAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEP 315
            G PG  G+ GP G+ G  GD+G +G  G PG PGP G+ G PG  G+ G PG  G +G  
Sbjct: 1327 GDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQ 1386

Query: 316  GKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPR 375
            G+ G  G+AG +G PG  G  G +G AG+ G  G  G PG +G  G PG  G  G  GP 
Sbjct: 1387 GEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPM 1446

Query: 376  GPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQ 435
            GP GLPG +G+         PG  G  G PGL GL GPPG  G KGDRG+ G  G  G +
Sbjct: 1447 GPPGLPGLKGD---------PGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAK 1497

Query: 436  GASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPG 490
            G  G  G AG  G  G  GLPGP+G  GN G  G  G +G  GLPG  G  GPPG
Sbjct: 1498 GDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1552



 Score =  309 bits (791), Expect = 6e-84
 Identities = 175/363 (48%), Positives = 196/363 (53%), Gaps = 40/363 (11%)

Query: 26   GPPGEQG------PPGPPGPPGVPGIDGIDGDRGPKGPPGPPGP---AGEPGKPGAPGKP 76
            GPPGE+G      P GPPGPPG  G  G +G  GP+GPPG  G     GE G+PG  G P
Sbjct: 1216 GPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNP 1275

Query: 77   GTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----RGIPGP---PGPPGTAGLP 129
            G PG  G+ GP G  G  G  G  G  G PG++G PG    +G PGP   PG PG  G P
Sbjct: 1276 GPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEP 1335

Query: 130  GELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHK 189
            G  G+ G  GD G  G PG PGPPGP G  G            PPG  G  G PG  G +
Sbjct: 1336 GPAGQDGVGGDKGEDGDPGQPGPPGPSGEAG------------PPGPPGKRGPPGAAGAE 1383

Query: 190  GAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEP 249
            G +GE G  G  G +G  G  G +G  G  G PG +GLRGI G VG++G  GA G DG P
Sbjct: 1384 GRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPP 1443

Query: 250  GPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMP 309
            GP G PG P   G +G PG  G KG  G  G  G PG  G KGD GLPG        G P
Sbjct: 1444 GPMGPPGLP---GLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQ------GSP 1494

Query: 310  GTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPP 369
            G KG+ G PGP   AG  G PG PG+PG +G  G KGSTG  G+ G  G  G PG  GPP
Sbjct: 1495 GAKGDGGIPGP---AGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPP 1551

Query: 370  GEV 372
            GEV
Sbjct: 1552 GEV 1554



 Score =  288 bits (738), Expect = 9e-78
 Identities = 190/473 (40%), Positives = 218/473 (46%), Gaps = 92/473 (19%)

Query: 232 GIVGDKGEKGARGLDGEPGP--QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPG 289
           G  G+KG+KG   +  EPG   +G PG  G  G  GPPG  GP G          PG PG
Sbjct: 432 GAYGEKGQKGEPAVV-EPGMLVEGPPGPAGPAGIMGPPGLQGPTGP---------PGDPG 481

Query: 290 PKGDTGLPGVDGRDGIPGMPGTK-------GEPGKPGPPGDAG--------LQGLPGVPG 334
            +G  G PG+ G DG+PG PGT        G  G  GP   A          Q    + G
Sbjct: 482 DRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRG 541

Query: 335 IPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPG 394
            PG  G+ G  G  G PG  G  G SG PG QGP G  GP GP G PG RG  G  G  G
Sbjct: 542 PPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRG 601

Query: 395 LPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIG 454
           +PG+ G+ G  G  GLPG PG  G +G+RG  G PGP G+ G  GE+GE G R      G
Sbjct: 602 MPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPR------G 655

Query: 455 LPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAP 514
           LPG    AG  G  G RG  G+ G PG+ G  GPPGP+G  G QG  G PG QG PG   
Sbjct: 656 LPG---EAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQ- 711

Query: 515 TDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRG 574
                                              G PGP GP GPPGE G  G+ G+ G
Sbjct: 712 -----------------------------------GLPGPQGPIGPPGEKGPQGKPGLAG 736

Query: 575 LPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPG------------ 621
           LPG  GPPG     G +G  GEKG  GPPG +GP G PG  G+ G  G            
Sbjct: 737 LPGADGPPGH---PGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKG 793

Query: 622 ----PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQR 670
               P   G  G  G+RG  G  G  G  GP GP G  G       + QAG++
Sbjct: 794 EDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEK 846



 Score =  213 bits (542), Expect = 5e-55
 Identities = 156/421 (37%), Positives = 178/421 (42%), Gaps = 95/421 (22%)

Query: 299 VDGRDGIPGMPGTKGE---------PGKP-GPPGDAGLQGLPGVPGIP----GAKGVAGE 344
           +DGRD    + G  GE           KP  PP +    G+P    I        G  GE
Sbjct: 377 IDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGE 436

Query: 345 KGSTGAPG--KPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSL 402
           KG  G P   +PG +        +GPPG  GP G  G PG +G  GP G PG  G  G  
Sbjct: 437 KGQKGEPAVVEPGML-------VEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRP 489

Query: 403 GSPGLPGLPGPPG----LP---GMKGDRGVV--------------------GEPGPKGEQ 435
           G PG  GLPGPPG    LP   G  G +G                      G PGP G  
Sbjct: 490 GLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLT 549

Query: 436 GASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQ 495
           G  G  G  G  G  G+ G PGP+G  G  G PG  G  G RG PG +G RG PG  G +
Sbjct: 550 GRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAK 609

Query: 496 GEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPP 555
           G++G  GLPG+ G                                 D G  G  G  GPP
Sbjct: 610 GDRGFDGLPGLPG---------------------------------DKGHRGERGPQGPP 636

Query: 556 GPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERG---PPG----RGPN 608
           GPPG  G  G  G++G RGLPG  GP G LG RG  G  G+ G  G   PPG     GP 
Sbjct: 637 GPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQ 696

Query: 609 GLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAG 668
           G PG  G  G+PGP      G  G +GP G  G  G  G PG  GLPG   P     + G
Sbjct: 697 GEPGPPGQQGNPGP-----QGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEG 751

Query: 669 Q 669
           Q
Sbjct: 752 Q 752



 Score =  153 bits (386), Expect = 6e-37
 Identities = 119/330 (36%), Positives = 136/330 (41%), Gaps = 80/330 (24%)

Query: 393 PGLPGK-------LGSLGSPGLPGLPGPPGL--PGMKGDRGVVGEPGPKGEQGASGEEGE 443
           PG+P +       +   G+ G  G  G P +  PGM     V G PGP G  G  G  G 
Sbjct: 415 PGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGML----VEGPPGPAGPAGIMGPPGL 470

Query: 444 AGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSR-------GLPGVEGP----------- 485
            G  G  GD G  GP G  G PG  GL GP G+        G  G +GP           
Sbjct: 471 QGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQA 530

Query: 486 ---------RGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAA 536
                    RGPPGP G+ G  G  G PG  G  G +                       
Sbjct: 531 ILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG---------------------- 568

Query: 537 SLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPG---IKGPPGALGLRGPKGD 593
                D G  G  G  GPPGP G PG+ G PG  G RG+PG    KG  G  GL G  GD
Sbjct: 569 -----DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGD 623

Query: 594 LGEKGERGPPGRGPNGLPGAIGLPGDPG-------PASYGRNGRDGERGPPGVAGIPGVP 646
            G +GERGP  +GP G PG  G+ G+ G       P   G  G  G RG PG  G PG+ 
Sbjct: 624 KGHRGERGP--QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMA 681

Query: 647 GPPGPPGLPGFCEPASCTMQAGQRAFNKGP 676
           G  GPPG  G   P       GQ+  N GP
Sbjct: 682 GVDGPPGPKGNMGPQGEPGPPGQQG-NPGP 710



 Score =  112 bits (281), Expect = 9e-25
 Identities = 66/143 (46%), Positives = 68/143 (47%), Gaps = 20/143 (13%)

Query: 17   GLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKP 76
            GL   A Q GPPG  GPPG PG  G PG  G  G  G  G  GPPG  GE G  G PG  
Sbjct: 1432 GLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQ 1491

Query: 77   GTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVG 136
            G+PGA               KG  G PG  G  G PG     PPG PG  G  G  G  G
Sbjct: 1492 GSPGA---------------KGDGGIPGPAGPLGPPG-----PPGLPGPQGPKGNKGSTG 1531

Query: 137  PVGDPGRRGPPGPPGPPGPRGTI 159
            P G  G  G PGPPG PGP G +
Sbjct: 1532 PAGQKGDSGLPGPPGSPGPPGEV 1554



 Score =  108 bits (269), Expect = 2e-23
 Identities = 57/126 (45%), Positives = 70/126 (55%), Gaps = 13/126 (10%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPG---PAGEPGKPGAPGKPGTPGAD 82
            G  G+ GPPGP GPPG+PG+ G  G +G KG PG  G   P GE G+ G  G PGT G+ 
Sbjct: 1435 GAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSP 1494

Query: 83   GLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----------RGIPGPPGPPGTAGLPGEL 132
            G  G  G PG  G  G  G PG+PG +G  G          +G  G PGPPG+ G PGE+
Sbjct: 1495 GAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1554

Query: 133  GRVGPV 138
             +  P+
Sbjct: 1555 IQPLPI 1560



 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 45/106 (42%), Positives = 50/106 (47%), Gaps = 15/106 (14%)

Query: 15   LLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPG 74
            L+GL     ++G  G++G PG  G PG  G  GI G  GP GPPGP              
Sbjct: 1469 LIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGP-------------- 1514

Query: 75   KPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPP 120
             PG PG  G  G  GS G  G KG  G PG PGS G PG  I   P
Sbjct: 1515 -PGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1559


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score =  526 bits (1355), Expect = e-149
 Identities = 321/769 (41%), Positives = 375/769 (48%), Gaps = 147/769 (19%)

Query: 17   GLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKP 76
            GL      +G  GE+GP GPPGPPG  G+ G DG+ GP+G PG  GP G  G  G PG P
Sbjct: 565  GLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAP 624

Query: 77   GTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGELGRV 135
            G P   G+ G DG PG  G+ G +GEPG PG +G PG +G+PGP GP G  G  G  G+ 
Sbjct: 625  GQP---GMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP 681

Query: 136  GPVGDPGRRGPPGPP------------GPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLP 183
            G  G PG  GPPG P            GPPGP+G IG+           P G  G  G+ 
Sbjct: 682  GLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPG---------PRGVKGADGVR 732

Query: 184  GMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGAR 243
            G++G KG KGE G PG +G  G +GD+GE+G++G +G  G +G +G  G  GD G  G  
Sbjct: 733  GLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQA 792

Query: 244  GLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGD------TGLP 297
            G  G+ G  GLPG PG QG +G  G  G  G  G +GARG+ G PGP+G        G  
Sbjct: 793  GEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSR 852

Query: 298  GVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQM 357
            G  G  G PG  GT G  G PGPPG+ G QG  G  G PG KG  G  G  G PG PGQ 
Sbjct: 853  GARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQR 912

Query: 358  GNSGKPGQQGPPGE---VGPRGP---------------------QGLPGSRGELGPVGSP 393
            G +G  G+ GPPG    VGP+GP                     QGLPG+ G+ G  G P
Sbjct: 913  GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP 972

Query: 394  GLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDI 453
            G  G  G  G  GL G PG  GLPG +G  G+ G  GP+G  G  G  GE G  G  G I
Sbjct: 973  GPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPI 1032

Query: 454  GLP------GPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGP---------------- 491
            GLP      GP G AG  G PG +GP+G  G  GV+GP G PGP                
Sbjct: 1033 GLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEI 1092

Query: 492  --------RGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDS 543
                    +G +GE G  G PG+QGP G         +   R  Q  F +      + D 
Sbjct: 1093 GEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQ------KGDE 1146

Query: 544  GATGLPGRPGP------PGPPGPPGENGFPGQMGIRGLPGIK------------------ 579
            GA G PG PGP      PGPPG  GENG  G MG  G PG +                  
Sbjct: 1147 GARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV 1206

Query: 580  ------------------GPPGALGLRGPKGDLGEKGERGPPGR-------------GPN 608
                              GPPG  G+ GPKG+ GEKGE GPPG              GP 
Sbjct: 1207 GSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPK 1266

Query: 609  GLPGAIGLPGDPG-PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
            G PG +G PGDPG P   G  G+DG  G  G  G PG PGPPGP G  G
Sbjct: 1267 GNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAG 1315



 Score =  526 bits (1354), Expect = e-149
 Identities = 309/691 (44%), Positives = 356/691 (51%), Gaps = 69/691 (9%)

Query: 23   AQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGAD 82
            A RGPPG  G  G PGP G PG  G  G+ G  GP GP G  G PG  G PGK G PGAD
Sbjct: 487  ALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD 546

Query: 83   GLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGELGRVGPVGDP 141
            G  G  G PG+ G +G  G PG+PG +G  G RG  GPPGPPG  G+ GE G +GP G P
Sbjct: 547  GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLP 606

Query: 142  GRRGP---------PGPP---------GPPGPRGTIGFHDGDPLCP----NACP---PGR 176
            G  GP         PG P         GPPGP+G +G   G+P  P    N  P   PG 
Sbjct: 607  GEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMG-PQGEPGPPGQQGNPGPQGLPGP 665

Query: 177  SGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGD 236
             G  G PG +G +G  G  G PG  G  G  G +G+ GE GA GPPG QG  G  G  G 
Sbjct: 666  QGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGV 725

Query: 237  KGEKGARGL---DGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGD 293
            KG  G RGL    GE G  G PG  GD G +G  GE G  G RG +G  G  G  GP GD
Sbjct: 726  KGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGD 785

Query: 294  TGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGK 353
             G  G  G  G  G+PG  G PG+ GP G  G  G PG  G  GA+GVAG+ G  G  G 
Sbjct: 786  PGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGP 845

Query: 354  PGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGP 413
             G  G+ G  G  G PG  G  G  G PG  GE GP G  G  G  G  G PG PG  G 
Sbjct: 846  TGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGL 905

Query: 414  PGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGP 473
            PG PG +G+ G  G+ GP G  G  G +G  GE G +G+ G PGP G  G  G PG  G 
Sbjct: 906  PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK 965

Query: 474  EGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAE 533
            EG++G PG +G  G  GP G++G  G  GLPG QG PG    +           Q     
Sbjct: 966  EGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP---------QGPPGP 1016

Query: 534  MAASLKRPDSGATG---LPGRPGPPGPPGPPGENGFPGQMGIR------------GLPGI 578
            + +  +R  +G  G   LPGRPGP GPPGP GE G PG+ G +            GLPG 
Sbjct: 1017 VGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGP 1076

Query: 579  KGPPGALGLRGPKGDLGE---------KGERGPPG----RGPNGLPGAIGLPGDPGPASY 625
             GP G+ G  G KG++GE         KGE GPPG    +GP G PG  G  G+PGP   
Sbjct: 1077 AGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPR-- 1134

Query: 626  GRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
            G+ G  G++G  G  G PG PGP G  GLPG
Sbjct: 1135 GQQGMFGQKGDEGARGFPGPPGPIGLQGLPG 1165



 Score =  516 bits (1330), Expect = e-146
 Identities = 320/739 (43%), Positives = 362/739 (48%), Gaps = 120/739 (16%)

Query: 26   GPPGEQGPPGPPGPPG---------VPGIDGIDGDRGPKGP---PGPPGPAGEPGKPGAP 73
            GP G  GP G PGP G         VPG+ G  G +GPKG    PG PG  GE G  G  
Sbjct: 775  GPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVA 834

Query: 74   GKPGTPGADGLTGPDGS---------PGSIGSKGQKGEPGVPGSRGFPGR-------GIP 117
            GKPG  G  G TGP GS         PG  G+ G  G PG PG RG  G        G  
Sbjct: 835  GKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPK 894

Query: 118  GPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGF--------HDGDPLCP 169
            GPPGPPG  GLPG  G+ G  G  G+ GPPGP G  GP+G  G         H G P   
Sbjct: 895  GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPP--- 951

Query: 170  NACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRG 229
               PPG  G PG  G  G KG  G  G  G+ G  G  G  GE G  GAQG PG +G  G
Sbjct: 952  --GPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEG 1009

Query: 230  ITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGP------PGEAGPKGDRGAEGARG 283
              G  G  G  G RG  G  GP GLPG PG QG  GP      PGE GP+G  G +G +G
Sbjct: 1010 PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQG 1069

Query: 284  IPGLPGPKGDTGLPGVDGRDGI---PGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGA-- 338
              GLPGP G  G PG DG  G    PG  G+KG+ G+ GPPG  GLQG  G PGI G   
Sbjct: 1070 PVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDG 1129

Query: 339  -------KGVAGEKGSTGA---------------PGKPGQMGNSGKPGQQGPPGEVGPRG 376
                   +G+ G+KG  GA               PG PG+ G +G  G  GPPG  GPRG
Sbjct: 1130 EPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRG 1189

Query: 377  PQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGM------KGDRGVVGEPG 430
            PQG  G+ G  GP GS G  G +G  G PG  G PGPPG  G+      +G++G  G PG
Sbjct: 1190 PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPG 1249

Query: 431  PKGEQGASGEEGEAGERGELGDIGLPGP------------------KGSAGNPGEPGLRG 472
              G  GA G  G+ G +G  G +G PG                   KG  G+PG+PG  G
Sbjct: 1250 AAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1309

Query: 473  PEGSRGLPGVEGPRGPPGPRGV---QGEQGATGLPGVQGPPGR-APTDQHIKQVCMRVIQ 528
            P G  G PG  G RGPPG  G    QGE+GA G  G +GPPG+  P              
Sbjct: 1310 PSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGP------QGPAG 1363

Query: 529  EHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLR 588
            +   E    +  P  G  GLPG  G  GPPGP G  G PG  G  G  G KG PG +GL 
Sbjct: 1364 KPGPEGLRGIPGP-VGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLI 1422

Query: 589  GPKGDLGEKGERGPPG-------RGPNGLP---GAIGLPGDPG-PASYGRNGRDGERGPP 637
            GP G+ GEKG+RG PG       +G  G+P   G +G PG PG P   G  G  G  GP 
Sbjct: 1423 GPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPA 1482

Query: 638  GVAGIPGVPGPPGPPGLPG 656
            G  G  G+PGPPG PG PG
Sbjct: 1483 GQKGDSGLPGPPGSPGPPG 1501



 Score =  505 bits (1300), Expect = e-143
 Identities = 298/694 (42%), Positives = 344/694 (49%), Gaps = 100/694 (14%)

Query: 31   QGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLTGPDGS 90
            +GPPGP GP G+          GP G  GP GP G+PG  G PG+PG PGADGL GP G+
Sbjct: 402  EGPPGPAGPAGI---------MGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGT 452

Query: 91   ----PGSIGSKGQKGEP--------------------GVPGSRGFPGRGIPGPPGPPGTA 126
                P   G  G KG                      G PG  G  GR  PGP G PG++
Sbjct: 453  MLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGR--PGPVGGPGSS 510

Query: 127  GLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGD--PLCPNA-CPPGRSGYPGLP 183
            G  GE G  GP G  G +GPPGP G PG RG  G   G   P  P A    G  G PGLP
Sbjct: 511  GAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLP 570

Query: 184  GMRGHKGAKGEIGEPGRQGHKGEEGDQGELGE------------VGAQGPPGAQGLRGIT 231
            G +GH+G +G  G PG  G  G  G+ GE+G             +G +G PGA G  G+ 
Sbjct: 571  GDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMA 630

Query: 232  GIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPK 291
            G+ G  G KG  G  GEPGP G  G PG QG  GP G  GP G++G +G  G+ GLPG  
Sbjct: 631  GVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD 690

Query: 292  GDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAP 351
            G  G PG +G+ G  G  G  G  G  G PG  G++G  GV G+ G+KG  GE G  G  
Sbjct: 691  GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK 750

Query: 352  GKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLP 411
            G  G  G+ G+ GQ GP GE GP GP+G  G  G+ GP G  G  GKLG  G PG PG  
Sbjct: 751  GDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQ 810

Query: 412  GP---------PGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSA 462
            GP         PG  G KG RGV G+PGP+G++G +G  G  G RG  G  G  G  G  
Sbjct: 811  GPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGD 870

Query: 463  GNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQ------GEQGATGLPGVQGPPGRAPTD 516
            G PG PG RGP+G +G  G  GP+GPPGP G        G++G TG  G  GPPG     
Sbjct: 871  GPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPG--- 927

Query: 517  QHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLP 576
                                   +  +G TG  G  G PGPPGPPGE G PG  G  G  
Sbjct: 928  ------------------GVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAK 969

Query: 577  GIKGPPGALGLRGPKGDLGEKGERGPP----------GRGPNGLPGAIGLPGDPGPAS-- 624
            G  GP G  G  GP G  G  GERG P          G GP G PG +G PG+ G A   
Sbjct: 970  GDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTA 1029

Query: 625  --YGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
               G  GR G +GPPG AG  G PG  GP G  G
Sbjct: 1030 GPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAG 1063



 Score =  484 bits (1245), Expect = e-136
 Identities = 281/617 (45%), Positives = 322/617 (52%), Gaps = 45/617 (7%)

Query: 24   QRGPPGEQGPPGPPGPPGVPGIDGIDGDRGP---KGPPGPPGPAGEPGKPGAPGKPGTPG 80
            QRG  G QG  GPPGP GV G  G  G+ GP   +G PGPPGP GE G PGA GK G  G
Sbjct: 911  QRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKG 970

Query: 81   ADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGE---LGRVG 136
              G  G  G  G  G +G  GE G+PG++G PG +G  GP GPPG  G PGE    G  G
Sbjct: 971  DPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAG 1030

Query: 137  PVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNAC-----PPGRSGYPGLPGMRGHKGA 191
            P+G PGR GP GPPGP G +G  G  +  P  P        P G  G  G  G  G  G 
Sbjct: 1031 PIGLPGRPGPQGPPGPAGEKGAPG--EKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGD 1088

Query: 192  KGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGP 251
            KGEIGEPG++G KG++G+ G  G  G QGP GA G+ G  G  G +G++G  G  G+ G 
Sbjct: 1089 KGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGA 1148

Query: 252  QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGT 311
            +G PG PG  G +G PG  G KG+ G  G  G PG PGP+G  G  G DG  G PG  G+
Sbjct: 1149 RGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGS 1208

Query: 312  KGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGE 371
             G  G+ G PG+AG  G PG  G+ G KG  GEKG  G PG  G  G  G PG  GP G 
Sbjct: 1209 VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1268

Query: 372  VGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGL---PGMKGDRGVVGE 428
             GP G  G PG  GE GP G  G+ G  G  G PG PG PGP G    PG  G RG  G 
Sbjct: 1269 PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGA 1328

Query: 429  PGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRG---PEGSRGLPGVEGP 485
             G +G QG  G +GEAG  G  G  G  GP+G AG PG  GLRG   P G +GLPG  G 
Sbjct: 1329 AGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQ 1388

Query: 486  RGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGA 545
             GPPGP       G  GLPG++G PG      H   + +        E          G+
Sbjct: 1389 DGPPGP------MGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGS 1442

Query: 546  TGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG- 604
             G  G  G PGP GP                   GPPG  GL GP+G  G KG  GP G 
Sbjct: 1443 PGAKGDGGIPGPAGP------------------LGPPGPPGLPGPQGPKGNKGSTGPAGQ 1484

Query: 605  RGPNGLPGAIGLPGDPG 621
            +G +GLPG  G PG PG
Sbjct: 1485 KGDSGLPGPPGSPGPPG 1501



 Score =  454 bits (1169), Expect = e-128
 Identities = 292/682 (42%), Positives = 339/682 (49%), Gaps = 113/682 (16%)

Query: 69   KPGAPGK----PGTPGADGLTGPD-GSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPP 123
            KP +P      PG P    +T       G+ G KGQKGEP V      PG  + GPPGP 
Sbjct: 353  KPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVE----PGMLVEGPPGPA 408

Query: 124  GTAGL---PGELGRVGPVGDPGRRGPPGPPGPPGPRGTIG----------FHDGD----- 165
            G AG+   PG  G  GP GDPG RGPPG PG PG  G  G           + GD     
Sbjct: 409  GPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGP 468

Query: 166  ------------------PLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEE 207
                               L     P G +G PG  G  G  GAKGE G+PG QG +G +
Sbjct: 469  TISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQ 528

Query: 208  GDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEP---------GPQGLPGAP 258
            G  G  G+ G +G PGA G RG+ G  G KG++G  GL G P         GPQG PG P
Sbjct: 529  GPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP 588

Query: 259  GDQGQRGPPGEAGPKGDRGAEGARGI---PGLPGPKGDTGLPGVDGRDGIPGMPGTKGEP 315
            GD G RG  GE GP+G  G  G RG+    G PG  G  G+ GVDG  G  G  G +GEP
Sbjct: 589  GDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEP 648

Query: 316  GKPGPPGDAGLQGLPGVP---GIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEV 372
            G PG  G+ G QGLPG     G PG KG  G+ G  G PG  G  G+ GK GQ G  G +
Sbjct: 649  GPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL 708

Query: 373  GPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPK 432
            GP GPQG  G  G  G  G+ G+ G  GS G  G  G PG  G  G+KGDRG VG+ GP+
Sbjct: 709  GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR 768

Query: 433  GEQGASGEE------------GEAGERGELGDIGLP------GPKGSAGNPGEPGLRGPE 474
            GE G  G +            G+AGE+G+LG  GLP      GPKGS G PG PG  G +
Sbjct: 769  GEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEK 828

Query: 475  GSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEM 534
            G+RG+ G  GPRG  GP G +G +GA G  G  GP G +  D                  
Sbjct: 829  GARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGD---------------GPP 873

Query: 535  AASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIK---GPPGALGLRGPK 591
                +R   G  G  G PGP GPPGPPG++G PG  G RG  G +   GPPG  G+ GP+
Sbjct: 874  GPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQ 933

Query: 592  ------GDLGEKGERGPPG-RGPNGLPGAI---GLPGDPGPASY-------GRNGRDGER 634
                  G +GE+G  GPPG  G  GLPGA    G  GDPGP          G  G  GER
Sbjct: 934  GPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGER 993

Query: 635  GPPGVAGIPGVPGPPGPPGLPG 656
            G PG  G PG+ G  GP G PG
Sbjct: 994  GLPGAQGAPGLKGGEGPQGPPG 1015



 Score =  386 bits (992), Expect = e-107
 Identities = 219/475 (46%), Positives = 244/475 (51%), Gaps = 44/475 (9%)

Query: 16   LGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGK 75
            +GL   A   G PGE G  G  G PG  G  G  G+ GP GPPG  GP G PG  G  G+
Sbjct: 1071 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGE 1130

Query: 76   PGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRV 135
            P         GP G  G  G KG +G            RG PGPPGP G  GLPG  G  
Sbjct: 1131 P---------GPRGQQGMFGQKGDEG-----------ARGFPGPPGPIGLQGLPGPPGEK 1170

Query: 136  GPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEI 195
            G  GD G  GPPGPPGP GP+G  G  DG        P G  G  G  G  G KG  GE 
Sbjct: 1171 GENGDVGPMGPPGPPGPRGPQGPNG-ADG--------PQGPPGSVGSVGGVGEKGEPGEA 1221

Query: 196  GEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLP 255
            G PG  G  G  G +GE GE G  GPPGA G  G  G  GD G K      G PGP G P
Sbjct: 1222 GNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPK------GNPGPVGFP 1275

Query: 256  GAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEP 315
            G PG  G+ GP G+ G  GD+G +G  G PG PGP G+ G PG  G+ G PG  G +G  
Sbjct: 1276 GDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQ 1335

Query: 316  GKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPR 375
            G+ G  G+AG +G PG  G  G +G AG+ G  G  G PG +G  G PG  G  G  GP 
Sbjct: 1336 GEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPM 1395

Query: 376  GPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQ 435
            GP GLPG +G+         PG  G  G PGL GL GPPG  G KGDRG+ G  G  G +
Sbjct: 1396 GPPGLPGLKGD---------PGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAK 1446

Query: 436  GASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPG 490
            G  G  G AG  G  G  GLPGP+G  GN G  G  G +G  GLPG  G  GPPG
Sbjct: 1447 GDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1501



 Score =  309 bits (791), Expect = 6e-84
 Identities = 175/363 (48%), Positives = 196/363 (53%), Gaps = 40/363 (11%)

Query: 26   GPPGEQG------PPGPPGPPGVPGIDGIDGDRGPKGPPGPPGP---AGEPGKPGAPGKP 76
            GPPGE+G      P GPPGPPG  G  G +G  GP+GPPG  G     GE G+PG  G P
Sbjct: 1165 GPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNP 1224

Query: 77   GTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----RGIPGP---PGPPGTAGLP 129
            G PG  G+ GP G  G  G  G  G  G PG++G PG    +G PGP   PG PG  G P
Sbjct: 1225 GPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEP 1284

Query: 130  GELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHK 189
            G  G+ G  GD G  G PG PGPPGP G  G            PPG  G  G PG  G +
Sbjct: 1285 GPAGQDGVGGDKGEDGDPGQPGPPGPSGEAG------------PPGPPGKRGPPGAAGAE 1332

Query: 190  GAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEP 249
            G +GE G  G  G +G  G  G +G  G  G PG +GLRGI G VG++G  GA G DG P
Sbjct: 1333 GRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPP 1392

Query: 250  GPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMP 309
            GP G PG P   G +G PG  G KG  G  G  G PG  G KGD GLPG        G P
Sbjct: 1393 GPMGPPGLP---GLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQ------GSP 1443

Query: 310  GTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPP 369
            G KG+ G PGP   AG  G PG PG+PG +G  G KGSTG  G+ G  G  G PG  GPP
Sbjct: 1444 GAKGDGGIPGP---AGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPP 1500

Query: 370  GEV 372
            GEV
Sbjct: 1501 GEV 1503



 Score =  288 bits (738), Expect = 9e-78
 Identities = 190/473 (40%), Positives = 218/473 (46%), Gaps = 92/473 (19%)

Query: 232 GIVGDKGEKGARGLDGEPGP--QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPG 289
           G  G+KG+KG   +  EPG   +G PG  G  G  GPPG  GP G          PG PG
Sbjct: 381 GAYGEKGQKGEPAVV-EPGMLVEGPPGPAGPAGIMGPPGLQGPTGP---------PGDPG 430

Query: 290 PKGDTGLPGVDGRDGIPGMPGTK-------GEPGKPGPPGDAG--------LQGLPGVPG 334
            +G  G PG+ G DG+PG PGT        G  G  GP   A          Q    + G
Sbjct: 431 DRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRG 490

Query: 335 IPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPG 394
            PG  G+ G  G  G PG  G  G SG PG QGP G  GP GP G PG RG  G  G  G
Sbjct: 491 PPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRG 550

Query: 395 LPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIG 454
           +PG+ G+ G  G  GLPG PG  G +G+RG  G PGP G+ G  GE+GE G R      G
Sbjct: 551 MPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPR------G 604

Query: 455 LPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAP 514
           LPG    AG  G  G RG  G+ G PG+ G  GPPGP+G  G QG  G PG QG PG   
Sbjct: 605 LPG---EAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQ- 660

Query: 515 TDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRG 574
                                              G PGP GP GPPGE G  G+ G+ G
Sbjct: 661 -----------------------------------GLPGPQGPIGPPGEKGPQGKPGLAG 685

Query: 575 LPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPG------------ 621
           LPG  GPPG     G +G  GEKG  GPPG +GP G PG  G+ G  G            
Sbjct: 686 LPGADGPPGH---PGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKG 742

Query: 622 ----PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQR 670
               P   G  G  G+RG  G  G  G  GP GP G  G       + QAG++
Sbjct: 743 EDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEK 795



 Score =  213 bits (542), Expect = 5e-55
 Identities = 156/421 (37%), Positives = 178/421 (42%), Gaps = 95/421 (22%)

Query: 299 VDGRDGIPGMPGTKGE---------PGKP-GPPGDAGLQGLPGVPGIP----GAKGVAGE 344
           +DGRD    + G  GE           KP  PP +    G+P    I        G  GE
Sbjct: 326 IDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGE 385

Query: 345 KGSTGAPG--KPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSL 402
           KG  G P   +PG +        +GPPG  GP G  G PG +G  GP G PG  G  G  
Sbjct: 386 KGQKGEPAVVEPGML-------VEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRP 438

Query: 403 GSPGLPGLPGPPG----LP---GMKGDRGVV--------------------GEPGPKGEQ 435
           G PG  GLPGPPG    LP   G  G +G                      G PGP G  
Sbjct: 439 GLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLT 498

Query: 436 GASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQ 495
           G  G  G  G  G  G+ G PGP+G  G  G PG  G  G RG PG +G RG PG  G +
Sbjct: 499 GRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAK 558

Query: 496 GEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPP 555
           G++G  GLPG+ G                                 D G  G  G  GPP
Sbjct: 559 GDRGFDGLPGLPG---------------------------------DKGHRGERGPQGPP 585

Query: 556 GPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERG---PPG----RGPN 608
           GPPG  G  G  G++G RGLPG  GP G LG RG  G  G+ G  G   PPG     GP 
Sbjct: 586 GPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQ 645

Query: 609 GLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAG 668
           G PG  G  G+PGP      G  G +GP G  G  G  G PG  GLPG   P     + G
Sbjct: 646 GEPGPPGQQGNPGP-----QGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEG 700

Query: 669 Q 669
           Q
Sbjct: 701 Q 701



 Score =  153 bits (386), Expect = 6e-37
 Identities = 119/330 (36%), Positives = 136/330 (41%), Gaps = 80/330 (24%)

Query: 393 PGLPGK-------LGSLGSPGLPGLPGPPGL--PGMKGDRGVVGEPGPKGEQGASGEEGE 443
           PG+P +       +   G+ G  G  G P +  PGM     V G PGP G  G  G  G 
Sbjct: 364 PGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGML----VEGPPGPAGPAGIMGPPGL 419

Query: 444 AGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSR-------GLPGVEGP----------- 485
            G  G  GD G  GP G  G PG  GL GP G+        G  G +GP           
Sbjct: 420 QGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQA 479

Query: 486 ---------RGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAA 536
                    RGPPGP G+ G  G  G PG  G  G +                       
Sbjct: 480 ILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG---------------------- 517

Query: 537 SLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPG---IKGPPGALGLRGPKGD 593
                D G  G  G  GPPGP G PG+ G PG  G RG+PG    KG  G  GL G  GD
Sbjct: 518 -----DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGD 572

Query: 594 LGEKGERGPPGRGPNGLPGAIGLPGDPG-------PASYGRNGRDGERGPPGVAGIPGVP 646
            G +GERGP  +GP G PG  G+ G+ G       P   G  G  G RG PG  G PG+ 
Sbjct: 573 KGHRGERGP--QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMA 630

Query: 647 GPPGPPGLPGFCEPASCTMQAGQRAFNKGP 676
           G  GPPG  G   P       GQ+  N GP
Sbjct: 631 GVDGPPGPKGNMGPQGEPGPPGQQG-NPGP 659



 Score =  112 bits (281), Expect = 9e-25
 Identities = 66/143 (46%), Positives = 68/143 (47%), Gaps = 20/143 (13%)

Query: 17   GLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKP 76
            GL   A Q GPPG  GPPG PG  G PG  G  G  G  G  GPPG  GE G  G PG  
Sbjct: 1381 GLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQ 1440

Query: 77   GTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVG 136
            G+PGA               KG  G PG  G  G PG     PPG PG  G  G  G  G
Sbjct: 1441 GSPGA---------------KGDGGIPGPAGPLGPPG-----PPGLPGPQGPKGNKGSTG 1480

Query: 137  PVGDPGRRGPPGPPGPPGPRGTI 159
            P G  G  G PGPPG PGP G +
Sbjct: 1481 PAGQKGDSGLPGPPGSPGPPGEV 1503



 Score =  108 bits (269), Expect = 2e-23
 Identities = 57/126 (45%), Positives = 70/126 (55%), Gaps = 13/126 (10%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPG---PAGEPGKPGAPGKPGTPGAD 82
            G  G+ GPPGP GPPG+PG+ G  G +G KG PG  G   P GE G+ G  G PGT G+ 
Sbjct: 1384 GAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSP 1443

Query: 83   GLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----------RGIPGPPGPPGTAGLPGEL 132
            G  G  G PG  G  G  G PG+PG +G  G          +G  G PGPPG+ G PGE+
Sbjct: 1444 GAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1503

Query: 133  GRVGPV 138
             +  P+
Sbjct: 1504 IQPLPI 1509



 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 45/106 (42%), Positives = 50/106 (47%), Gaps = 15/106 (14%)

Query: 15   LLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPG 74
            L+GL     ++G  G++G PG  G PG  G  GI G  GP GPPGP              
Sbjct: 1418 LIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGP-------------- 1463

Query: 75   KPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPP 120
             PG PG  G  G  GS G  G KG  G PG PGS G PG  I   P
Sbjct: 1464 -PGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1508


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score =  526 bits (1355), Expect = e-149
 Identities = 321/769 (41%), Positives = 375/769 (48%), Gaps = 147/769 (19%)

Query: 17   GLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKP 76
            GL      +G  GE+GP GPPGPPG  G+ G DG+ GP+G PG  GP G  G  G PG P
Sbjct: 604  GLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAP 663

Query: 77   GTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGELGRV 135
            G P   G+ G DG PG  G+ G +GEPG PG +G PG +G+PGP GP G  G  G  G+ 
Sbjct: 664  GQP---GMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKP 720

Query: 136  GPVGDPGRRGPPGPP------------GPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLP 183
            G  G PG  GPPG P            GPPGP+G IG+           P G  G  G+ 
Sbjct: 721  GLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPG---------PRGVKGADGVR 771

Query: 184  GMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGAR 243
            G++G KG KGE G PG +G  G +GD+GE+G++G +G  G +G +G  G  GD G  G  
Sbjct: 772  GLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQA 831

Query: 244  GLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGD------TGLP 297
            G  G+ G  GLPG PG QG +G  G  G  G  G +GARG+ G PGP+G        G  
Sbjct: 832  GEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSR 891

Query: 298  GVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQM 357
            G  G  G PG  GT G  G PGPPG+ G QG  G  G PG KG  G  G  G PG PGQ 
Sbjct: 892  GARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQR 951

Query: 358  GNSGKPGQQGPPGE---VGPRGP---------------------QGLPGSRGELGPVGSP 393
            G +G  G+ GPPG    VGP+GP                     QGLPG+ G+ G  G P
Sbjct: 952  GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP 1011

Query: 394  GLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDI 453
            G  G  G  G  GL G PG  GLPG +G  G+ G  GP+G  G  G  GE G  G  G I
Sbjct: 1012 GPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPI 1071

Query: 454  GLP------GPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGP---------------- 491
            GLP      GP G AG  G PG +GP+G  G  GV+GP G PGP                
Sbjct: 1072 GLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEI 1131

Query: 492  --------RGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDS 543
                    +G +GE G  G PG+QGP G         +   R  Q  F +      + D 
Sbjct: 1132 GEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQ------KGDE 1185

Query: 544  GATGLPGRPGP------PGPPGPPGENGFPGQMGIRGLPGIK------------------ 579
            GA G PG PGP      PGPPG  GENG  G MG  G PG +                  
Sbjct: 1186 GARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV 1245

Query: 580  ------------------GPPGALGLRGPKGDLGEKGERGPPGR-------------GPN 608
                              GPPG  G+ GPKG+ GEKGE GPPG              GP 
Sbjct: 1246 GSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPK 1305

Query: 609  GLPGAIGLPGDPG-PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
            G PG +G PGDPG P   G  G+DG  G  G  G PG PGPPGP G  G
Sbjct: 1306 GNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAG 1354



 Score =  526 bits (1354), Expect = e-149
 Identities = 309/691 (44%), Positives = 356/691 (51%), Gaps = 69/691 (9%)

Query: 23   AQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGAD 82
            A RGPPG  G  G PGP G PG  G  G+ G  GP GP G  G PG  G PGK G PGAD
Sbjct: 526  ALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD 585

Query: 83   GLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGELGRVGPVGDP 141
            G  G  G PG+ G +G  G PG+PG +G  G RG  GPPGPPG  G+ GE G +GP G P
Sbjct: 586  GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLP 645

Query: 142  GRRGP---------PGPP---------GPPGPRGTIGFHDGDPLCP----NACP---PGR 176
            G  GP         PG P         GPPGP+G +G   G+P  P    N  P   PG 
Sbjct: 646  GEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMG-PQGEPGPPGQQGNPGPQGLPGP 704

Query: 177  SGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGD 236
             G  G PG +G +G  G  G PG  G  G  G +G+ GE GA GPPG QG  G  G  G 
Sbjct: 705  QGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGV 764

Query: 237  KGEKGARGL---DGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGD 293
            KG  G RGL    GE G  G PG  GD G +G  GE G  G RG +G  G  G  GP GD
Sbjct: 765  KGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGD 824

Query: 294  TGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGK 353
             G  G  G  G  G+PG  G PG+ GP G  G  G PG  G  GA+GVAG+ G  G  G 
Sbjct: 825  PGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGP 884

Query: 354  PGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGP 413
             G  G+ G  G  G PG  G  G  G PG  GE GP G  G  G  G  G PG PG  G 
Sbjct: 885  TGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGL 944

Query: 414  PGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGP 473
            PG PG +G+ G  G+ GP G  G  G +G  GE G +G+ G PGP G  G  G PG  G 
Sbjct: 945  PGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK 1004

Query: 474  EGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAE 533
            EG++G PG +G  G  GP G++G  G  GLPG QG PG    +           Q     
Sbjct: 1005 EGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP---------QGPPGP 1055

Query: 534  MAASLKRPDSGATG---LPGRPGPPGPPGPPGENGFPGQMGIR------------GLPGI 578
            + +  +R  +G  G   LPGRPGP GPPGP GE G PG+ G +            GLPG 
Sbjct: 1056 VGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGP 1115

Query: 579  KGPPGALGLRGPKGDLGE---------KGERGPPG----RGPNGLPGAIGLPGDPGPASY 625
             GP G+ G  G KG++GE         KGE GPPG    +GP G PG  G  G+PGP   
Sbjct: 1116 AGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPR-- 1173

Query: 626  GRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
            G+ G  G++G  G  G PG PGP G  GLPG
Sbjct: 1174 GQQGMFGQKGDEGARGFPGPPGPIGLQGLPG 1204



 Score =  516 bits (1330), Expect = e-146
 Identities = 320/739 (43%), Positives = 362/739 (48%), Gaps = 120/739 (16%)

Query: 26   GPPGEQGPPGPPGPPG---------VPGIDGIDGDRGPKGP---PGPPGPAGEPGKPGAP 73
            GP G  GP G PGP G         VPG+ G  G +GPKG    PG PG  GE G  G  
Sbjct: 814  GPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVA 873

Query: 74   GKPGTPGADGLTGPDGS---------PGSIGSKGQKGEPGVPGSRGFPGR-------GIP 117
            GKPG  G  G TGP GS         PG  G+ G  G PG PG RG  G        G  
Sbjct: 874  GKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPK 933

Query: 118  GPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGF--------HDGDPLCP 169
            GPPGPPG  GLPG  G+ G  G  G+ GPPGP G  GP+G  G         H G P   
Sbjct: 934  GPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPP--- 990

Query: 170  NACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRG 229
               PPG  G PG  G  G KG  G  G  G+ G  G  G  GE G  GAQG PG +G  G
Sbjct: 991  --GPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEG 1048

Query: 230  ITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGP------PGEAGPKGDRGAEGARG 283
              G  G  G  G RG  G  GP GLPG PG QG  GP      PGE GP+G  G +G +G
Sbjct: 1049 PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQG 1108

Query: 284  IPGLPGPKGDTGLPGVDGRDGI---PGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGA-- 338
              GLPGP G  G PG DG  G    PG  G+KG+ G+ GPPG  GLQG  G PGI G   
Sbjct: 1109 PVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDG 1168

Query: 339  -------KGVAGEKGSTGA---------------PGKPGQMGNSGKPGQQGPPGEVGPRG 376
                   +G+ G+KG  GA               PG PG+ G +G  G  GPPG  GPRG
Sbjct: 1169 EPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRG 1228

Query: 377  PQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGM------KGDRGVVGEPG 430
            PQG  G+ G  GP GS G  G +G  G PG  G PGPPG  G+      +G++G  G PG
Sbjct: 1229 PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPG 1288

Query: 431  PKGEQGASGEEGEAGERGELGDIGLPGP------------------KGSAGNPGEPGLRG 472
              G  GA G  G+ G +G  G +G PG                   KG  G+PG+PG  G
Sbjct: 1289 AAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPG 1348

Query: 473  PEGSRGLPGVEGPRGPPGPRGV---QGEQGATGLPGVQGPPGR-APTDQHIKQVCMRVIQ 528
            P G  G PG  G RGPPG  G    QGE+GA G  G +GPPG+  P              
Sbjct: 1349 PSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGP------QGPAG 1402

Query: 529  EHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLR 588
            +   E    +  P  G  GLPG  G  GPPGP G  G PG  G  G  G KG PG +GL 
Sbjct: 1403 KPGPEGLRGIPGP-VGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLI 1461

Query: 589  GPKGDLGEKGERGPPG-------RGPNGLP---GAIGLPGDPG-PASYGRNGRDGERGPP 637
            GP G+ GEKG+RG PG       +G  G+P   G +G PG PG P   G  G  G  GP 
Sbjct: 1462 GPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPA 1521

Query: 638  GVAGIPGVPGPPGPPGLPG 656
            G  G  G+PGPPG PG PG
Sbjct: 1522 GQKGDSGLPGPPGSPGPPG 1540



 Score =  505 bits (1300), Expect = e-143
 Identities = 298/694 (42%), Positives = 344/694 (49%), Gaps = 100/694 (14%)

Query: 31   QGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLTGPDGS 90
            +GPPGP GP G+          GP G  GP GP G+PG  G PG+PG PGADGL GP G+
Sbjct: 441  EGPPGPAGPAGI---------MGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGT 491

Query: 91   ----PGSIGSKGQKGEP--------------------GVPGSRGFPGRGIPGPPGPPGTA 126
                P   G  G KG                      G PG  G  GR  PGP G PG++
Sbjct: 492  MLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGR--PGPVGGPGSS 549

Query: 127  GLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGD--PLCPNA-CPPGRSGYPGLP 183
            G  GE G  GP G  G +GPPGP G PG RG  G   G   P  P A    G  G PGLP
Sbjct: 550  GAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLP 609

Query: 184  GMRGHKGAKGEIGEPGRQGHKGEEGDQGELGE------------VGAQGPPGAQGLRGIT 231
            G +GH+G +G  G PG  G  G  G+ GE+G             +G +G PGA G  G+ 
Sbjct: 610  GDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMA 669

Query: 232  GIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPK 291
            G+ G  G KG  G  GEPGP G  G PG QG  GP G  GP G++G +G  G+ GLPG  
Sbjct: 670  GVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGAD 729

Query: 292  GDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAP 351
            G  G PG +G+ G  G  G  G  G  G PG  G++G  GV G+ G+KG  GE G  G  
Sbjct: 730  GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFK 789

Query: 352  GKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLP 411
            G  G  G+ G+ GQ GP GE GP GP+G  G  G+ GP G  G  GKLG  G PG PG  
Sbjct: 790  GDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQ 849

Query: 412  GP---------PGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSA 462
            GP         PG  G KG RGV G+PGP+G++G +G  G  G RG  G  G  G  G  
Sbjct: 850  GPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGD 909

Query: 463  GNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQ------GEQGATGLPGVQGPPGRAPTD 516
            G PG PG RGP+G +G  G  GP+GPPGP G        G++G TG  G  GPPG     
Sbjct: 910  GPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPG--- 966

Query: 517  QHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLP 576
                                   +  +G TG  G  G PGPPGPPGE G PG  G  G  
Sbjct: 967  ------------------GVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAK 1008

Query: 577  GIKGPPGALGLRGPKGDLGEKGERGPP----------GRGPNGLPGAIGLPGDPGPAS-- 624
            G  GP G  G  GP G  G  GERG P          G GP G PG +G PG+ G A   
Sbjct: 1009 GDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTA 1068

Query: 625  --YGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
               G  GR G +GPPG AG  G PG  GP G  G
Sbjct: 1069 GPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAG 1102



 Score =  484 bits (1245), Expect = e-136
 Identities = 281/617 (45%), Positives = 322/617 (52%), Gaps = 45/617 (7%)

Query: 24   QRGPPGEQGPPGPPGPPGVPGIDGIDGDRGP---KGPPGPPGPAGEPGKPGAPGKPGTPG 80
            QRG  G QG  GPPGP GV G  G  G+ GP   +G PGPPGP GE G PGA GK G  G
Sbjct: 950  QRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKG 1009

Query: 81   ADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGE---LGRVG 136
              G  G  G  G  G +G  GE G+PG++G PG +G  GP GPPG  G PGE    G  G
Sbjct: 1010 DPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAG 1069

Query: 137  PVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNAC-----PPGRSGYPGLPGMRGHKGA 191
            P+G PGR GP GPPGP G +G  G  +  P  P        P G  G  G  G  G  G 
Sbjct: 1070 PIGLPGRPGPQGPPGPAGEKGAPG--EKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGD 1127

Query: 192  KGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGP 251
            KGEIGEPG++G KG++G+ G  G  G QGP GA G+ G  G  G +G++G  G  G+ G 
Sbjct: 1128 KGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGA 1187

Query: 252  QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGT 311
            +G PG PG  G +G PG  G KG+ G  G  G PG PGP+G  G  G DG  G PG  G+
Sbjct: 1188 RGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGS 1247

Query: 312  KGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGE 371
             G  G+ G PG+AG  G PG  G+ G KG  GEKG  G PG  G  G  G PG  GP G 
Sbjct: 1248 VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1307

Query: 372  VGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGL---PGMKGDRGVVGE 428
             GP G  G PG  GE GP G  G+ G  G  G PG PG PGP G    PG  G RG  G 
Sbjct: 1308 PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGA 1367

Query: 429  PGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRG---PEGSRGLPGVEGP 485
             G +G QG  G +GEAG  G  G  G  GP+G AG PG  GLRG   P G +GLPG  G 
Sbjct: 1368 AGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQ 1427

Query: 486  RGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGA 545
             GPPGP       G  GLPG++G PG      H   + +        E          G+
Sbjct: 1428 DGPPGP------MGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGS 1481

Query: 546  TGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG- 604
             G  G  G PGP GP                   GPPG  GL GP+G  G KG  GP G 
Sbjct: 1482 PGAKGDGGIPGPAGP------------------LGPPGPPGLPGPQGPKGNKGSTGPAGQ 1523

Query: 605  RGPNGLPGAIGLPGDPG 621
            +G +GLPG  G PG PG
Sbjct: 1524 KGDSGLPGPPGSPGPPG 1540



 Score =  454 bits (1169), Expect = e-128
 Identities = 292/682 (42%), Positives = 339/682 (49%), Gaps = 113/682 (16%)

Query: 69   KPGAPGK----PGTPGADGLTGPD-GSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPP 123
            KP +P      PG P    +T       G+ G KGQKGEP V      PG  + GPPGP 
Sbjct: 392  KPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVE----PGMLVEGPPGPA 447

Query: 124  GTAGL---PGELGRVGPVGDPGRRGPPGPPGPPGPRGTIG----------FHDGD----- 165
            G AG+   PG  G  GP GDPG RGPPG PG PG  G  G           + GD     
Sbjct: 448  GPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGP 507

Query: 166  ------------------PLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEE 207
                               L     P G +G PG  G  G  GAKGE G+PG QG +G +
Sbjct: 508  TISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQ 567

Query: 208  GDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEP---------GPQGLPGAP 258
            G  G  G+ G +G PGA G RG+ G  G KG++G  GL G P         GPQG PG P
Sbjct: 568  GPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP 627

Query: 259  GDQGQRGPPGEAGPKGDRGAEGARGI---PGLPGPKGDTGLPGVDGRDGIPGMPGTKGEP 315
            GD G RG  GE GP+G  G  G RG+    G PG  G  G+ GVDG  G  G  G +GEP
Sbjct: 628  GDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEP 687

Query: 316  GKPGPPGDAGLQGLPGVP---GIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEV 372
            G PG  G+ G QGLPG     G PG KG  G+ G  G PG  G  G+ GK GQ G  G +
Sbjct: 688  GPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL 747

Query: 373  GPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPK 432
            GP GPQG  G  G  G  G+ G+ G  GS G  G  G PG  G  G+KGDRG VG+ GP+
Sbjct: 748  GPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPR 807

Query: 433  GEQGASGEE------------GEAGERGELGDIGLP------GPKGSAGNPGEPGLRGPE 474
            GE G  G +            G+AGE+G+LG  GLP      GPKGS G PG PG  G +
Sbjct: 808  GEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEK 867

Query: 475  GSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEM 534
            G+RG+ G  GPRG  GP G +G +GA G  G  GP G +  D                  
Sbjct: 868  GARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGD---------------GPP 912

Query: 535  AASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIK---GPPGALGLRGPK 591
                +R   G  G  G PGP GPPGPPG++G PG  G RG  G +   GPPG  G+ GP+
Sbjct: 913  GPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQ 972

Query: 592  ------GDLGEKGERGPPG-RGPNGLPGAI---GLPGDPGPASY-------GRNGRDGER 634
                  G +GE+G  GPPG  G  GLPGA    G  GDPGP          G  G  GER
Sbjct: 973  GPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGER 1032

Query: 635  GPPGVAGIPGVPGPPGPPGLPG 656
            G PG  G PG+ G  GP G PG
Sbjct: 1033 GLPGAQGAPGLKGGEGPQGPPG 1054



 Score =  386 bits (992), Expect = e-107
 Identities = 219/475 (46%), Positives = 244/475 (51%), Gaps = 44/475 (9%)

Query: 16   LGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGK 75
            +GL   A   G PGE G  G  G PG  G  G  G+ GP GPPG  GP G PG  G  G+
Sbjct: 1110 VGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGE 1169

Query: 76   PGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRV 135
            P         GP G  G  G KG +G            RG PGPPGP G  GLPG  G  
Sbjct: 1170 P---------GPRGQQGMFGQKGDEG-----------ARGFPGPPGPIGLQGLPGPPGEK 1209

Query: 136  GPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEI 195
            G  GD G  GPPGPPGP GP+G  G  DG        P G  G  G  G  G KG  GE 
Sbjct: 1210 GENGDVGPMGPPGPPGPRGPQGPNG-ADG--------PQGPPGSVGSVGGVGEKGEPGEA 1260

Query: 196  GEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLP 255
            G PG  G  G  G +GE GE G  GPPGA G  G  G  GD G K      G PGP G P
Sbjct: 1261 GNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPK------GNPGPVGFP 1314

Query: 256  GAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEP 315
            G PG  G+ GP G+ G  GD+G +G  G PG PGP G+ G PG  G+ G PG  G +G  
Sbjct: 1315 GDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQ 1374

Query: 316  GKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPR 375
            G+ G  G+AG +G PG  G  G +G AG+ G  G  G PG +G  G PG  G  G  GP 
Sbjct: 1375 GEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPM 1434

Query: 376  GPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQ 435
            GP GLPG +G+         PG  G  G PGL GL GPPG  G KGDRG+ G  G  G +
Sbjct: 1435 GPPGLPGLKGD---------PGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAK 1485

Query: 436  GASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPG 490
            G  G  G AG  G  G  GLPGP+G  GN G  G  G +G  GLPG  G  GPPG
Sbjct: 1486 GDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPG 1540



 Score =  309 bits (791), Expect = 6e-84
 Identities = 175/363 (48%), Positives = 196/363 (53%), Gaps = 40/363 (11%)

Query: 26   GPPGEQG------PPGPPGPPGVPGIDGIDGDRGPKGPPGPPGP---AGEPGKPGAPGKP 76
            GPPGE+G      P GPPGPPG  G  G +G  GP+GPPG  G     GE G+PG  G P
Sbjct: 1204 GPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNP 1263

Query: 77   GTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----RGIPGP---PGPPGTAGLP 129
            G PG  G+ GP G  G  G  G  G  G PG++G PG    +G PGP   PG PG  G P
Sbjct: 1264 GPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEP 1323

Query: 130  GELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHK 189
            G  G+ G  GD G  G PG PGPPGP G  G            PPG  G  G PG  G +
Sbjct: 1324 GPAGQDGVGGDKGEDGDPGQPGPPGPSGEAG------------PPGPPGKRGPPGAAGAE 1371

Query: 190  GAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEP 249
            G +GE G  G  G +G  G  G +G  G  G PG +GLRGI G VG++G  GA G DG P
Sbjct: 1372 GRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPP 1431

Query: 250  GPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMP 309
            GP G PG P   G +G PG  G KG  G  G  G PG  G KGD GLPG        G P
Sbjct: 1432 GPMGPPGLP---GLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQ------GSP 1482

Query: 310  GTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPP 369
            G KG+ G PGP   AG  G PG PG+PG +G  G KGSTG  G+ G  G  G PG  GPP
Sbjct: 1483 GAKGDGGIPGP---AGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPP 1539

Query: 370  GEV 372
            GEV
Sbjct: 1540 GEV 1542



 Score =  288 bits (738), Expect = 9e-78
 Identities = 190/473 (40%), Positives = 218/473 (46%), Gaps = 92/473 (19%)

Query: 232 GIVGDKGEKGARGLDGEPGP--QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPG 289
           G  G+KG+KG   +  EPG   +G PG  G  G  GPPG  GP G          PG PG
Sbjct: 420 GAYGEKGQKGEPAVV-EPGMLVEGPPGPAGPAGIMGPPGLQGPTGP---------PGDPG 469

Query: 290 PKGDTGLPGVDGRDGIPGMPGTK-------GEPGKPGPPGDAG--------LQGLPGVPG 334
            +G  G PG+ G DG+PG PGT        G  G  GP   A          Q    + G
Sbjct: 470 DRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRG 529

Query: 335 IPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPG 394
            PG  G+ G  G  G PG  G  G SG PG QGP G  GP GP G PG RG  G  G  G
Sbjct: 530 PPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRG 589

Query: 395 LPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIG 454
           +PG+ G+ G  G  GLPG PG  G +G+RG  G PGP G+ G  GE+GE G R      G
Sbjct: 590 MPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPR------G 643

Query: 455 LPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAP 514
           LPG    AG  G  G RG  G+ G PG+ G  GPPGP+G  G QG  G PG QG PG   
Sbjct: 644 LPG---EAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQ- 699

Query: 515 TDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRG 574
                                              G PGP GP GPPGE G  G+ G+ G
Sbjct: 700 -----------------------------------GLPGPQGPIGPPGEKGPQGKPGLAG 724

Query: 575 LPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPG------------ 621
           LPG  GPPG     G +G  GEKG  GPPG +GP G PG  G+ G  G            
Sbjct: 725 LPGADGPPGH---PGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKG 781

Query: 622 ----PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQR 670
               P   G  G  G+RG  G  G  G  GP GP G  G       + QAG++
Sbjct: 782 EDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEK 834



 Score =  213 bits (542), Expect = 5e-55
 Identities = 156/421 (37%), Positives = 178/421 (42%), Gaps = 95/421 (22%)

Query: 299 VDGRDGIPGMPGTKGE---------PGKP-GPPGDAGLQGLPGVPGIP----GAKGVAGE 344
           +DGRD    + G  GE           KP  PP +    G+P    I        G  GE
Sbjct: 365 IDGRDSDLLVDGDLGEYDFYEYKEYEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGE 424

Query: 345 KGSTGAPG--KPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSL 402
           KG  G P   +PG +        +GPPG  GP G  G PG +G  GP G PG  G  G  
Sbjct: 425 KGQKGEPAVVEPGML-------VEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRP 477

Query: 403 GSPGLPGLPGPPG----LP---GMKGDRGVV--------------------GEPGPKGEQ 435
           G PG  GLPGPPG    LP   G  G +G                      G PGP G  
Sbjct: 478 GLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLT 537

Query: 436 GASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQ 495
           G  G  G  G  G  G+ G PGP+G  G  G PG  G  G RG PG +G RG PG  G +
Sbjct: 538 GRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAK 597

Query: 496 GEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPP 555
           G++G  GLPG+ G                                 D G  G  G  GPP
Sbjct: 598 GDRGFDGLPGLPG---------------------------------DKGHRGERGPQGPP 624

Query: 556 GPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERG---PPG----RGPN 608
           GPPG  G  G  G++G RGLPG  GP G LG RG  G  G+ G  G   PPG     GP 
Sbjct: 625 GPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQ 684

Query: 609 GLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAG 668
           G PG  G  G+PGP      G  G +GP G  G  G  G PG  GLPG   P     + G
Sbjct: 685 GEPGPPGQQGNPGP-----QGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEG 739

Query: 669 Q 669
           Q
Sbjct: 740 Q 740



 Score =  153 bits (386), Expect = 6e-37
 Identities = 119/330 (36%), Positives = 136/330 (41%), Gaps = 80/330 (24%)

Query: 393 PGLPGK-------LGSLGSPGLPGLPGPPGL--PGMKGDRGVVGEPGPKGEQGASGEEGE 443
           PG+P +       +   G+ G  G  G P +  PGM     V G PGP G  G  G  G 
Sbjct: 403 PGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGML----VEGPPGPAGPAGIMGPPGL 458

Query: 444 AGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSR-------GLPGVEGP----------- 485
            G  G  GD G  GP G  G PG  GL GP G+        G  G +GP           
Sbjct: 459 QGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQA 518

Query: 486 ---------RGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAA 536
                    RGPPGP G+ G  G  G PG  G  G +                       
Sbjct: 519 ILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG---------------------- 556

Query: 537 SLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPG---IKGPPGALGLRGPKGD 593
                D G  G  G  GPPGP G PG+ G PG  G RG+PG    KG  G  GL G  GD
Sbjct: 557 -----DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGD 611

Query: 594 LGEKGERGPPGRGPNGLPGAIGLPGDPG-------PASYGRNGRDGERGPPGVAGIPGVP 646
            G +GERGP  +GP G PG  G+ G+ G       P   G  G  G RG PG  G PG+ 
Sbjct: 612 KGHRGERGP--QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMA 669

Query: 647 GPPGPPGLPGFCEPASCTMQAGQRAFNKGP 676
           G  GPPG  G   P       GQ+  N GP
Sbjct: 670 GVDGPPGPKGNMGPQGEPGPPGQQG-NPGP 698



 Score =  112 bits (281), Expect = 9e-25
 Identities = 66/143 (46%), Positives = 68/143 (47%), Gaps = 20/143 (13%)

Query: 17   GLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKP 76
            GL   A Q GPPG  GPPG PG  G PG  G  G  G  G  GPPG  GE G  G PG  
Sbjct: 1420 GLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQ 1479

Query: 77   GTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVG 136
            G+PGA               KG  G PG  G  G PG     PPG PG  G  G  G  G
Sbjct: 1480 GSPGA---------------KGDGGIPGPAGPLGPPG-----PPGLPGPQGPKGNKGSTG 1519

Query: 137  PVGDPGRRGPPGPPGPPGPRGTI 159
            P G  G  G PGPPG PGP G +
Sbjct: 1520 PAGQKGDSGLPGPPGSPGPPGEV 1542



 Score =  108 bits (269), Expect = 2e-23
 Identities = 57/126 (45%), Positives = 70/126 (55%), Gaps = 13/126 (10%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPG---PAGEPGKPGAPGKPGTPGAD 82
            G  G+ GPPGP GPPG+PG+ G  G +G KG PG  G   P GE G+ G  G PGT G+ 
Sbjct: 1423 GAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSP 1482

Query: 83   GLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----------RGIPGPPGPPGTAGLPGEL 132
            G  G  G PG  G  G  G PG+PG +G  G          +G  G PGPPG+ G PGE+
Sbjct: 1483 GAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1542

Query: 133  GRVGPV 138
             +  P+
Sbjct: 1543 IQPLPI 1548



 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 45/106 (42%), Positives = 50/106 (47%), Gaps = 15/106 (14%)

Query: 15   LLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPG 74
            L+GL     ++G  G++G PG  G PG  G  GI G  GP GPPGP              
Sbjct: 1457 LIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGP-------------- 1502

Query: 75   KPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPP 120
             PG PG  G  G  GS G  G KG  G PG PGS G PG  I   P
Sbjct: 1503 -PGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLP 1547


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score =  525 bits (1351), Expect = e-149
 Identities = 325/754 (43%), Positives = 374/754 (49%), Gaps = 157/754 (20%)

Query: 24   QRGPPGEQGPPGPPGPPGVPGIDG-------------IDGDRGPKGPPGPPGPAGEPGKP 70
            Q GPPG+QGPPG PG PG  G  G             IDG RGP GP GPPG  G PG+P
Sbjct: 435  QPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQP 494

Query: 71   GAPGKPGTPGADGLTG---PDGSPGSIGS----------------KGQKGEPGVPGSRGF 111
            GA G  G PG DG+ G   P G+PG IG                 KG KG+PG PG  G 
Sbjct: 495  GAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGM 554

Query: 112  PGR----------GIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPG--PRGTI 159
             GR          G+PGP G PG+ GL GE G  G VG PG RG  GPPGPPG  P G I
Sbjct: 555  TGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPI 614

Query: 160  GFHD-----------------GDP--LCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGR 200
            G                    G+P  + P   PPG  G PG PG  G +G +G  G PGR
Sbjct: 615  GDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGR 674

Query: 201  QGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGD 260
             G  GE+G  G+ G +G  GPPG +G+ G+ G      + G  G  G PG  GLPG PG 
Sbjct: 675  PGLPGEKGAVGQPG-IGFPGPPGPKGVDGLPG------DMGPPGTPGRPGFNGLPGNPGV 727

Query: 261  QGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGP 320
            QGQ+G PG  G  G +G  G  GIPG PG KG  G+PGV G  G  G PG +G  G+PGP
Sbjct: 728  QGQKGEPG-VGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGP 786

Query: 321  PGDAGLQGLPGVPGI--PGAKGVAGEKGSTGAPGKPGQMGNSGKPG-------------- 364
            PG  G  G PGVPGI  PGA+G  G +G  G  G PG  G  G PG              
Sbjct: 787  PGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKG 846

Query: 365  QQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGP---PGLPGMKG 421
             QG PG  G  G  GLPG +G  G  G PG  G++G +G+PG PG PGP   PGLPG KG
Sbjct: 847  AQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKG 906

Query: 422  DRGVVGEPGPKGEQGASGEEGEAG---------------------ERGELGDIGLPGPKG 460
            D G  G  GP+G+ G  G++G+ G                     ++GE G IG  G KG
Sbjct: 907  DHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKG 966

Query: 461  SAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIK 520
            S G+PG PG+ G +G  G PG  GP+G PG   + G  GA GLPG +G  G         
Sbjct: 967  SRGDPGTPGVPGKDGQAGQPGQPGPKGDPG---ISGTPGAPGLPGPKGSVG--------- 1014

Query: 521  QVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKG 580
                                   G  G PG  G PG PGP G  G PG  G +G  G  G
Sbjct: 1015 ---------------------GMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAG 1053

Query: 581  PPGA--LGLRGPKGDLGEKGERGPPGR-------GPNGLPGAIGLPGDPG----PASYGR 627
            PPG    GLRG KGD G  G  G PG        G  G+PG+ GL G PG    P S G 
Sbjct: 1054 PPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGL 1113

Query: 628  NGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPA 661
             G  G++G PG+ GIPGV G  G PG PG   PA
Sbjct: 1114 PGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPA 1147



 Score =  519 bits (1337), Expect = e-147
 Identities = 327/791 (41%), Positives = 381/791 (48%), Gaps = 162/791 (20%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 85
            GP G++G PG PG PG+PG  G  G  G  G PGPPGP G  G PG  G PGTPG  G  
Sbjct: 661  GPQGDRGFPGTPGRPGLPGEKGAVGQPGI-GFPGPPGPKGVDGLPGDMGPPGTPGRPGFN 719

Query: 86   GPDGSPGSIGSKGQKGEPGV--PGSRGFPGR-GIPGPPGPPGTAGLPGELGRVGPVGDPG 142
            G  G+PG    +GQKGEPGV  PG +G PG  GIPG PG  G+ G+PG  G  G +G PG
Sbjct: 720  GLPGNPGV---QGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPG 776

Query: 143  RRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPG---LPGMRGHKGAKGEIG--- 196
             +G  G PGPPG  G++G     P  P   PPG  G PG    PG+ G  G KGE G   
Sbjct: 777  LQGIRGEPGPPGLPGSVG----SPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPG 832

Query: 197  -----EPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPG- 250
                  PG +G KG +G  G  G+ G  G PG QG  GI G  G KGE G  G  G+PG 
Sbjct: 833  FPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGS 892

Query: 251  --PQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPG------------------- 289
              P G PG PG++G  G PG +GP+GD G +G +G  GLPG                   
Sbjct: 893  PGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGD 952

Query: 290  --------PKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKG- 340
                    P G+ G  G  G  G+PG  G  G+PG+PGP GD G+ G PG PG+PG KG 
Sbjct: 953  QGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGS 1012

Query: 341  -----VAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGL--------------- 380
                 + G  G  G PG PG  G+ G PG +G  GE G  GP G+               
Sbjct: 1013 VGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIA 1072

Query: 381  -----PGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGE---PGPK 432
                 PG +GE G +G PG+PG  G  GSPG  G PG PGLPG KGD+G+ G    PG K
Sbjct: 1073 GFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVK 1132

Query: 433  GEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGL-----------RGPEGSRGLPG 481
            GE G  G  G  G  G+ G+ G  G  GSAG  GEPGL           +G +GS+G  G
Sbjct: 1133 GEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVG 1192

Query: 482  VEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRP 541
              G  G PG  G +GEQG  G PG QG PG   +  H             A       R 
Sbjct: 1193 FPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGH-------------ATEGPKGDRG 1239

Query: 542  DSGATGLPGRPGPPGPPGPPG------ENGFPGQMGIRGLPGIKGPPGALGLRGPKGD-- 593
              G  GLPG PGP GPPG PG      + G PG  G  G+PG KG PG  G+ G  G   
Sbjct: 1240 PQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPG 1299

Query: 594  -LGEKGERGPPG-------------------RGPNGLPGAIGLPGDPGPAS-----YGRN 628
              G KG+ GPPG                   +G  G+PGA GLPG PGP        G  
Sbjct: 1300 ITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEP 1359

Query: 629  GRDGERGPPGVAGIPGVPGP---------------------PGPPGLPGFCEPASCTMQA 667
            G  G  GPPG+ G+ G+PGP                      G PG  G   PA  T   
Sbjct: 1360 GLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPT--- 1416

Query: 668  GQRAFNKGPDP 678
            G R F   P P
Sbjct: 1417 GPRGFPGPPGP 1427



 Score =  519 bits (1336), Expect = e-147
 Identities = 314/718 (43%), Positives = 368/718 (51%), Gaps = 126/718 (17%)

Query: 24   QRGPPG---------EQGPPGPPG--PPGVPGIDGIDGDRGPKGPPGPPGPAGEPGK--- 69
            +RGPPG         + GPPGPPG  P G  G  G  G  G  G PG PGP GEPGK   
Sbjct: 584  ERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVP 643

Query: 70   -PGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGL 128
             PG PG  G PG+ G  GP G  G  G+ G+ G PG  G+ G PG G PGPPGP G  GL
Sbjct: 644  LPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGL 703

Query: 129  PGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGH 188
            PG++G  G  G PG  G PG PG  G +G           P    PG  G PGLPG+ G 
Sbjct: 704  PGDMGPPGTPGRPGFNGLPGNPGVQGQKGE----------PGVGLPGLKGLPGLPGIPGT 753

Query: 189  KGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGE 248
             G KG IG PG  G  G  G  G  G  G  GPPG  G  G  G+ G  G  GARG  G 
Sbjct: 754  PGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGI-GPPGARGPPGG 812

Query: 249  PGPQGLPGAPGDQGQRGPPG-----EAGPKGDRGAEGARGI------PGLPGPKGDTGLP 297
             GP GL G PG +G++G PG       GPKGD+GA+G  GI      PGLPG +G  G+P
Sbjct: 813  QGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIP 872

Query: 298  GVDGRDGIPGMPGTKGEPGKPGP------PGDAGLQGLPGVPGIPGAKGVAGEKGSTGAP 351
            G  G  G  G+ GT G+PG PGP      PG+ G  G PG  G  G  G+ G+KG  G P
Sbjct: 873  GFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLP 932

Query: 352  GKPGQM------------GNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKL 399
            GKPG M            G+ G+ GQ GP GE G RG  G PG  G+ G  G PG PG  
Sbjct: 933  GKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPK 992

Query: 400  GS---LGSPGLPGLPGPPG------LPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGEL 450
            G     G+PG PGLPGP G      LPG  G++GV G PGP+G  G  G++G  GE+G+ 
Sbjct: 993  GDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQA 1052

Query: 451  G--DIGLPGPKGS------AGNPGEPGLRGPEGSRGLPGVEGPR---------GPPGPRG 493
            G   IG+PG +G       AG PG PG +G +GS G+PG+ G           G PG  G
Sbjct: 1053 GPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPG 1112

Query: 494  VQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPG 553
            + GE+G  GLPG+ G PG                                G  GLPG PG
Sbjct: 1113 LPGEKGDKGLPGLDGIPG------------------------------VKGEAGLPGTPG 1142

Query: 554  PPGP---PGPPGENGFPGQMGIRGLPGIKGP-----PGALGLRGPKGDLGEKGERGPPG- 604
            P GP    G PG +G PG  G +G PG+ G      PGA G +G KG++G  G  G PG 
Sbjct: 1143 PTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGI 1202

Query: 605  ------RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
                  +G  G PG  G PG PG   +   G  G+RGP G  G+PG+PGP GPPGLPG
Sbjct: 1203 PGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPG 1260



 Score =  517 bits (1331), Expect = e-146
 Identities = 307/705 (43%), Positives = 361/705 (51%), Gaps = 90/705 (12%)

Query: 8    RGALGLLLLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPG------PP 61
            +G  G+ L GL      +G PG  G PG PG  G  G+ G+ G+ G  GPPG       P
Sbjct: 731  KGEPGVGLPGL------KGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEP 784

Query: 62   GPAGEPGKPGAPGKP--GTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGP 119
            GP G PG  G+PG P  G PGA G  G  G PG  G  G KGE G P   GFPG  +PGP
Sbjct: 785  GPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFP---GFPGLDMPGP 841

Query: 120  PGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGY 179
             G  G  GLPG  G+ G  G PG++G PG PG PG +G +G   G P  P +  PG  G 
Sbjct: 842  KGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVM-GTPGQPGS--PGPVGA 898

Query: 180  PGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGE 239
            PGLPG +G  G  G  G  G  G KG++GD G  G+ G+        ++G  G  G+KG+
Sbjct: 899  PGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQ 958

Query: 240  KGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDT---GL 296
             G  G  G  G  G PG PG  GQ G PG+ GPKGD G  G  G PGLPGPKG     GL
Sbjct: 959  IGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGL 1018

Query: 297  PGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVP--GIPGAKGVAGEKGSTGAPGKP 354
            PG  G  G+PG+PG +G PG PG  G  G +G  G P  GIPG +G  G++G  G PG P
Sbjct: 1019 PGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSP 1078

Query: 355  GQMGNS---------GKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSP 405
            G+ G           G PG +G PG VG  G  GLPG +G+ G  G  G+PG  G  G P
Sbjct: 1079 GEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLP 1138

Query: 406  GLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGE-----EGEAGERGELGDIGLPGPKG 460
            G PG  GP G  G  G  G+ G  G KGE G  G       G  G++G  G++G PG  G
Sbjct: 1139 GTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAG 1198

Query: 461  SAGNP---GEPGLRGPEGSRGLPGVEG-----PRGPPGPRGVQGEQGATGLPGVQGPPGR 512
            S G P   GE G  GP G +G PG+ G       GP G RG QG+ G  GLPG  GPPG 
Sbjct: 1199 SPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGL 1258

Query: 513  APTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFP---GQ 569
               D                       + D G  G PG PG PGP G PG  G P   G 
Sbjct: 1259 PGIDG---------------------VKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGS 1297

Query: 570  MGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPAS----- 624
             GI G  G  GPPG  G +GPKG  G +G +G   +G  G+PGA GLPG PGP       
Sbjct: 1298 PGITGSKGDMGPPGVPGFQGPKGLPGLQGIKG--DQGDQGVPGAKGLPGPPGPPGPYDII 1355

Query: 625  YGRNGRDGERGPPGVAGIPGVPGP------------PGPPGLPGF 657
             G  G  G  GPPG+ G+ G+PGP            PGPPG+PGF
Sbjct: 1356 KGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGF 1400



 Score =  506 bits (1304), Expect = e-143
 Identities = 329/823 (39%), Positives = 391/823 (47%), Gaps = 202/823 (24%)

Query: 7   DRGALGLLLLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGP---PGPPGP 63
           +RG  GL   G+      +GP G QGPPG  G  G PG+ G  G RGP G    PG PG 
Sbjct: 50  ERGLPGLQ--GVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGL 107

Query: 64  AGEPGKPGAPGKPGTPGADGLTG---PDGSPGSIGSKGQKGEPGVPGSRGFPG------- 113
            G PG+ G PG PG PG +G  G   P G PG  G  G  G PG+PG +G PG       
Sbjct: 108 PGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVP 167

Query: 114 -------RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDP 166
                  RG PG PG PG  GLPG  G VGP G  G  GPPGPPGPPG +G +G     P
Sbjct: 168 GMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGP 227

Query: 167 LCPNACPPGRSGYPGLPGM-----------RGHKGAK-----------GEIGEPGRQGHK 204
                   G SG PG+PG            +G KG K           GE GEPG+ G +
Sbjct: 228 KGDKG-DQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPR 286

Query: 205 GEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQR 264
           G+ G  G+ GE G+ G PG  G  G+ G  G +GEKG  G  G PG     G  G++G+R
Sbjct: 287 GKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGER 346

Query: 265 GPPGEAGPKGDRGAEGARGIPGLPGP--------------------KGD-----TGLPGV 299
           G PG  GP+G+ G +G  G+PG PGP                    KGD     T LPG 
Sbjct: 347 GYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGP 406

Query: 300 DGRDGIPGMPGTKGEPG-----------KPGPPGDAGLQGLPGVPGIPGAKGVAGEKGST 348
            GRDG+PG PG+ G PG           +PGPPGD G  G+PG PG  G  G  G+KG +
Sbjct: 407 SGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGES 466

Query: 349 ----------------------GAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGL---PGS 383
                                 G PG+PG  G+ G PG+ G  G  GP+G  GL   PG+
Sbjct: 467 CLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGA 526

Query: 384 RGELGPV----------------GSPGLPGKLGSLGSPGLPGLPGPPGLP---GMKGDRG 424
           +GE G                  G PG+ G+ GS G  G PGLPGP G P   G+KG+RG
Sbjct: 527 KGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERG 586

Query: 425 V---VGEPGPKGEQGAS-----------GEEGEAGERGELGDIGLPGPKGSAGN----PG 466
               VG PG +G+ G             G++G+AG  G  G  GLPGPKG  G     PG
Sbjct: 587 PPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPG 646

Query: 467 EPGLRGPEGSRGLPGVEGPR---GPPGPRGVQGEQGATGLPGV--QGPPGRAPTDQHIKQ 521
            PG  G  GS G PG +G R   G PG  G+ GE+GA G PG+   GPPG          
Sbjct: 647 PPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPG---------- 696

Query: 522 VCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIR-------- 573
                                 G  GLPG  GPPG PG PG NG PG  G++        
Sbjct: 697 --------------------PKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGV 736

Query: 574 GLPGIKGPPGALGLRGPKGDL---------GEKGERGPPG-------RGPNGLPGAIGLP 617
           GLPG+KG PG  G+ G  G+          GE G  GPPG        GP GLPG++G P
Sbjct: 737 GLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSP 796

Query: 618 GDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEP 660
           G PG    G  G  G +GPPG++G PG+ G  G PG PG   P
Sbjct: 797 GVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMP 839



 Score =  499 bits (1284), Expect = e-141
 Identities = 314/754 (41%), Positives = 381/754 (50%), Gaps = 140/754 (18%)

Query: 29   GEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPG---------PAGEPGKPGAPGKPGTP 79
            GE+G PG PGP G PG DG  G++G  G PG PG         P GE G+ G PG PG  
Sbjct: 275  GEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIV 334

Query: 80   ------GADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELG 133
                  G  G  G  G+PG  G  G KG PG+PG  G PG  +PG  G P   G PGE G
Sbjct: 335  IGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAP---GFPGERG 391

Query: 134  RVGPVGDP--------GRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGM 185
              G  G P        GR G PGPPG PGP G  G+ +G   C    PPG  G PG+PG 
Sbjct: 392  EKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPG-PPGDQGPPGIPGQ 450

Query: 186  RGHKGAKGEIGEPGR-------QGHKGEEGDQGELGEVGAQGPPGAQGLRGI---TGIVG 235
             G  G  GE G+ G         G++G  G QG  GE+G  G PGA+G RG+    G+ G
Sbjct: 451  PGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAG 510

Query: 236  DKGEKGARGLDGEPGPQGLPG-------APGDQGQRGPPGEAGPKGDRGAEGARGIPGLP 288
              G +G  GL G+PG +G PG         GD+G  G PG+ G  G  G+ G  G PGLP
Sbjct: 511  VPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLP 570

Query: 289  GPKGDTGLPGVDGRDGIP---GMPGTKGEPGKPGPP-----------GDAGLQGLPGVPG 334
            GPKG  G  G+ G  G P   G PG++G+ G PGPP           G AG  G PG PG
Sbjct: 571  GPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPG 630

Query: 335  IPGAKGVAGE-------------KGSTGAPGKPGQMGNSGKPGQQGPPGE---------- 371
            +PG KG  G+              GS G PG  G  G  G PG+ G PGE          
Sbjct: 631  LPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIG 690

Query: 372  -VGPRGPQGLPGSRGELGPVGSPGLPGKLG--------------SLGSPGLPGLPGPPGL 416
              GP GP+G+ G  G++GP G+PG PG  G               +G PGL GLPG PG+
Sbjct: 691  FPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGI 750

Query: 417  PGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGS 476
            PG  G++G +G PG  GE GA G  G  G RGE G  GLP   GS G+PG PG+ GP G+
Sbjct: 751  PGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLP---GSVGSPGVPGI-GPPGA 806

Query: 477  RGLPGVEGPRGPPGPRGVQGEQGATGLPGVQ--GPPGRAPTDQHIKQVCMRVIQEHFAEM 534
            RG PG +GP G  GP G++GE+G  G PG+   GP G    D+  + +     Q     +
Sbjct: 807  RGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKG----DKGAQGLPGITGQSGLPGL 862

Query: 535  AASLKRP----------DSGATGLPGRPGPPGP------PGPPGENGFPGQMGIRGLPGI 578
                  P          + G  G PG+PG PGP      PG  G++GFPG  G RG PG+
Sbjct: 863  PGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGL 922

Query: 579  KGPPGALGL---------------RGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGP 622
            KG  G +GL               +G KGD GEKG+ GP G +G  G PG  G+PG  G 
Sbjct: 923  KGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQ 982

Query: 623  ASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
            A  G+ G+ G +G PG++G PG PG PGP G  G
Sbjct: 983  A--GQPGQPGPKGDPGISGTPGAPGLPGPKGSVG 1014



 Score =  474 bits (1221), Expect = e-134
 Identities = 293/681 (43%), Positives = 341/681 (50%), Gaps = 132/681 (19%)

Query: 25   RGPPGEQGPPGPPGPPGV------PGIDGID-----GDRGPKGPPGPPGPAGEPGKPG-- 71
            RGPPG QGPPG  GPPG+      PG  G+D     GD+G +G PG  G +G PG PG  
Sbjct: 807  RGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQ 866

Query: 72   -APGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRG---FPG----RGIPGPPGPP 123
             APG PG PG+ G  G  G+PG  GS G  G PG+PG +G   FPG    RG PG  G  
Sbjct: 867  GAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDK 926

Query: 124  GTAGLPG---------------------ELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFH 162
            G  GLPG                     E G++GP+G+ G RG PG PG PG  G  G  
Sbjct: 927  GDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAG-Q 985

Query: 163  DGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEG------------DQ 210
             G P  P    PG SG PG PG+ G KG+ G +G PG  G KG  G            D+
Sbjct: 986  PGQP-GPKG-DPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDK 1043

Query: 211  GELGEVGAQGPPGA-----------QGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPG 259
            G  GE G  GPPG            QG+ G  G  G+KGEKG+ G+ G PG  GL G+PG
Sbjct: 1044 GAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPG 1103

Query: 260  DQGQRGPPGEAGPKGDRGAEGARGIPGL---------PGPKGDTGLPGVDGRDGIPGMPG 310
              G  G PG  G KGD+G  G  GIPG+         PGP G  G  G  G DGIPG  G
Sbjct: 1104 SVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAG 1163

Query: 311  TKGEPGKPG--------PPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGK 362
             KGEPG PG          GD G +G  G PG+ G+ G+ G KG  G  G PG  G  G 
Sbjct: 1164 EKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGL 1223

Query: 363  PGQQG--PPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMK 420
            PG  G    G  G RGPQG PG  G  GP+G PGLPG  G  G  G PG PG PG+PG K
Sbjct: 1224 PGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPK 1283

Query: 421  GDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLP 480
            GD      PG +G  G  G  G  G +G++G  G+PG +G  G PG  G++G +G +G+P
Sbjct: 1284 GD------PGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVP 1337

Query: 481  GVEGPRGPPGPRGVQG-EQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLK 539
            G +G  GPPGP G     +G  GLPG +GPP                             
Sbjct: 1338 GAKGLPGPPGPPGPYDIIKGEPGLPGPEGPP----------------------------- 1368

Query: 540  RPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGE 599
                G  GL G PGP G  G  G  G PG  GI   PG  G PG  G  GP G  G +G 
Sbjct: 1369 ----GLKGLQGLPGPKGQQGVTGLVGIPGPPGI---PGFDGAPGQKGEMGPAGPTGPRGF 1421

Query: 600  RGPPGRGPNGLPGAIGLPGDP 620
             GPP  GP+GLPG++G PG P
Sbjct: 1422 PGPP--GPDGLPGSMGPPGTP 1440



 Score =  402 bits (1034), Expect = e-112
 Identities = 235/518 (45%), Positives = 268/518 (51%), Gaps = 68/518 (13%)

Query: 24   QRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGK-------- 75
            Q GP GE+G  G PG PGVPG DG  G  G  GP G PG +G PG PG PG         
Sbjct: 958  QIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMG 1017

Query: 76   -PGTPG---ADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGE 131
             PGTPG     G+ GP GSPG  G KG KGE G  G  G    G+ G  G  G AG PG 
Sbjct: 1018 LPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGS 1077

Query: 132  LGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGA 191
             G  G  G  G  G PG PG  G  G++G+     L      PG  G  GLPG+ G  G 
Sbjct: 1078 PGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGL------PGEKGDKGLPGLDGIPGV 1131

Query: 192  KGEIGEPGRQG------HKGEEGDQGELGEVGAQGPPG--AQGLRGITGIVGDKGEKGAR 243
            KGE G PG  G       KGE G  G  G  G +G PG   +G  G  G  GDKG KG  
Sbjct: 1132 KGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEV 1191

Query: 244  GLDGEPGPQGLPGAPGDQGQRGPPGEAG--------------PKGDRGAEGARGIPGLPG 289
            G  G  G  G+PG+ G+QG  GPPG  G              PKGDRG +G  G+PGLPG
Sbjct: 1192 GFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPG 1251

Query: 290  PKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTG 349
            P G  GLPG+DG  G  G PG  G PG PGP GD G QG+PG+ G P   G+ G KG  G
Sbjct: 1252 PMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSP---GITGSKGDMG 1308

Query: 350  APGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSL-GSPGLP 408
             PG PG  G  G PG QG  G+   +G QG+PG++G  GP   PG PG    + G PGLP
Sbjct: 1309 PPGVPGFQGPKGLPGLQGIKGD---QGDQGVPGAKGLPGP---PGPPGPYDIIKGEPGLP 1362

Query: 409  GLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEP 468
            G  GPPGL G++      G PGPKG+QG +G             +G+PGP G  G  G P
Sbjct: 1363 GPEGPPGLKGLQ------GLPGPKGQQGVTGL------------VGIPGPPGIPGFDGAP 1404

Query: 469  GLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGV 506
            G +G  G  G  G  G  GPPGP G+ G  G  G P V
Sbjct: 1405 GQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTPSV 1442



 Score =  367 bits (943), Expect = e-101
 Identities = 243/593 (40%), Positives = 290/593 (48%), Gaps = 103/593 (17%)

Query: 178 GYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRG---ITGIV 234
           G  G  G RG  G +G IG PG QG +G +G  G+ G+ G  G PG +G RG    +G  
Sbjct: 43  GVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYP 102

Query: 235 GDKGEKGARGLDGEPGPQGLPGAPGDQGQR---------------GPPGEAGPKGDRG-- 277
           G+ G  G  G DG PGP G+PG  G +G+R               GPPG  G KGD G  
Sbjct: 103 GNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEI 162

Query: 278 --------AEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPP-------- 321
                    +G RG PG+PG  G  GLPG+ G  G PG  G  G PG PGPP        
Sbjct: 163 LGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGL 222

Query: 322 ------GDAGLQGLPGVPGIPG-----------AKGVAGEKGSTGAPGKP--GQMGNSGK 362
                 GD G QG+ G PG+PG            KG  G+KG  G  G P  G+ G  GK
Sbjct: 223 SFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGK 282

Query: 363 PGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLP----- 417
           PG +G PG+ G +G +G PG  GE    G PGL G+ G  G  G  G PGPPG+      
Sbjct: 283 PGPRGKPGKDGDKGEKGSPGFPGE---PGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGP 339

Query: 418 -GMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGS 476
            G KG+RG  G PGP+GE G  G  G  G+    G  GLP P G AG PG PG RG +G 
Sbjct: 340 LGEKGERGYPGTPGPRGEPGPKGFPGLPGQP---GPPGLPVP-GQAGAPGFPGERGEKGD 395

Query: 477 RGLPGV--------EGPRGPPGPRGVQGEQGAT--------GLPGVQGPPGRAPTDQHIK 520
           RG PG         +G  GPPG  G  G+ G T        G PG QGPPG       I 
Sbjct: 396 RGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIG 455

Query: 521 QVCMRVIQEHFAEMAASLK--RPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGI 578
           ++  +  Q+  + +   +   R   G  G PG  G PG PG  G+ G PG+ G+ G+PG 
Sbjct: 456 EIGEKG-QKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGP 514

Query: 579 KGPPGALGLRGPKGDLGE-------KGERGPPG-------RGPNGLPGAIGLPGDPGP-A 623
           +G PG +G  G KG+ GE       KG++G PG        G  G PG  G PG PGP  
Sbjct: 515 QGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKG 574

Query: 624 SYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGP 676
           S G  G  GERGPPG  G PG  G  GPPG PG+  PA      GQ  F  GP
Sbjct: 575 SPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGY-GPAGPIGDKGQAGFPGGP 626



 Score =  223 bits (567), Expect = 6e-58
 Identities = 131/312 (41%), Positives = 155/312 (49%), Gaps = 44/312 (14%)

Query: 4    TARDRGALGLLLLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGP 63
            +A ++G  GL   G       +G  G +G  G PG  G PGI G  G++G  GPPGP G 
Sbjct: 1161 SAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQ 1220

Query: 64   AGEPGKP-----------GAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFP 112
             G PG P           G  G+PG PG  G  GP G PG  G KG KG PG PG+    
Sbjct: 1221 PGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGA---- 1276

Query: 113  GRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNAC 172
              G+PGP G PG  G+PG  G  G  G  G  GPPG PG  GP+                
Sbjct: 1277 -PGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPK---------------- 1319

Query: 173  PPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGEL----GEVGAQGPPGAQGLR 228
                    GLPG++G KG +G+ G PG +G  G  G  G      GE G  GP G  GL+
Sbjct: 1320 --------GLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLK 1371

Query: 229  GITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLP 288
            G+ G+ G KG++G  GL G PGP G+PG  G  GQ+G  G AGP G RG  G  G  GLP
Sbjct: 1372 GLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLP 1431

Query: 289  GPKGDTGLPGVD 300
            G  G  G P VD
Sbjct: 1432 GSMGPPGTPSVD 1443


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score =  523 bits (1348), Expect = e-148
 Identities = 308/711 (43%), Positives = 360/711 (50%), Gaps = 79/711 (11%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGA---PGKPGTPGAD 82
            G PGE+G  G  G  G PG  G DG+RG +GPPGP G AGEPG  G     G PG  G  
Sbjct: 557  GLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRP 616

Query: 83   GLTGPDGSPGSIGSKGQKGEPGVPG------SRGFPGR----GIPGPPGPPGTAGLPGEL 132
            G+TG DG+PG+ G+ G  GEPG PG      S+G PG     G PG  GPPG  G+PG  
Sbjct: 617  GVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLP 676

Query: 133  GRVGPVGDPGRRGPPG------------PPGPPGPRGTIGFHDGDPLCPNACPPGRSGYP 180
            G  GP+G PG  GP G            PPG PGPRG  G      L       G  G+P
Sbjct: 677  GSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFP 736

Query: 181  GLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLR---GITGIVGDK 237
            G  G  G KG +G+ G PG +G  G EG +G+ G+ G +GPPG+ G +   G+ G+ G  
Sbjct: 737  GFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYP 796

Query: 238  GEKGARGLDGEPGPQGLPGAPGDQGQRGPP---GEAGPKGDRGAEGARGIPGLPGPKGDT 294
            G  G +G  G PGP G  G  G  G+ G P   GE GP G RG  G  G  G PGPKGD 
Sbjct: 797  GRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDV 856

Query: 295  GLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKP 354
            G  G  G  G  G+PG +G PG PGP G  G QG  G PG PG +G  G +G TG PG  
Sbjct: 857  GQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPA 916

Query: 355  GQMGNSGKP------GQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLP 408
            G +G  GK       G++GPPG  GP G QGLPG  G  G  G  G PG LG  G  GL 
Sbjct: 917  GVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLR 976

Query: 409  GLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEP 468
            G PGP G PG  G  G+ G+ GP G  GA+G  GE G  G  G IGLPG  GS G  G  
Sbjct: 977  GFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPA 1036

Query: 469  GLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQ 528
            G +G  G RG PG  G  G PGP G  G  GA G  G +G  G      H          
Sbjct: 1037 GKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGH---------- 1086

Query: 529  EHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQM------------GIRGLP 576
                   +   + D+G  G PG  GP G PGPPG +G  G+             G+RG  
Sbjct: 1087 -----KGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFV 1141

Query: 577  GIKGPPGALGLRGP---KGDLGEKGERGPPG----RGPNGLPGAIGLPGDPG----PASY 625
            G+ GPPG  GL GP   KG++G+ G  GP G    RGP G  G+ G PG PG    P + 
Sbjct: 1142 GVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAV 1201

Query: 626  GRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGP 676
            G  G  G+ G PG  G PG+PGP G  G  G   P+      G+    KGP
Sbjct: 1202 GEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGK----KGP 1248



 Score =  518 bits (1335), Expect = e-147
 Identities = 301/673 (44%), Positives = 346/673 (51%), Gaps = 69/673 (10%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGP---PGPAGEPGKPGAPGKPGTPGAD 82
            GP GE+G  G  G PG+ G  G  G RG +G PG    PGP G+ G+ GAPG PG  G  
Sbjct: 812  GPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLP 871

Query: 83   GLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR-GIPGPPGPPGTAGLPGELGRVGPVGDP 141
            GL GP G PG  G  G +G+ G PG  G  G  G  G  GPPG AG+ G  G+ G VG  
Sbjct: 872  GLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPL 931

Query: 142  GRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQ 201
            G RGPPGPPGPPG +G  G    +       PPG  G  G  G+RG  G KG  G+PG  
Sbjct: 932  GERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPT 991

Query: 202  GHKGEEGDQGEL------GEVGAQGPPGAQGLRGITGI---VGDKGEKGARGLDGEPGPQ 252
            G KG++G  G +      GE G  GP G  GL G +G    VG  G+KG+RG  G PGP 
Sbjct: 992  GLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPT 1051

Query: 253  GLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTK 312
            G  G PG  G  GPPG AGP G+ G +G  G PG  G KGD       G  G PG PG +
Sbjct: 1052 GKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGD------KGDAGPPGQPGIR 1105

Query: 313  GEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEV 372
            G  G PGPPG  G QG  G PG+ G KG  G +G  G  G PG  G  G PG++G  G+V
Sbjct: 1106 GPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDV 1165

Query: 373  GPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGL------------PGLPGPPGLPGMK 420
            G  GP G PG RG  GP GS G PG  G +G PG             PG PG PG+PG K
Sbjct: 1166 GSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPK 1225

Query: 421  GDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLP 480
            GD G  G+ GP G  G  G++G  GE G  G +G  G  G  G PG+PG+ G +GS G  
Sbjct: 1226 GDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEK 1285

Query: 481  GVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKR 540
            G  G  G PGP G  GE GA G PG +GP G                      M    + 
Sbjct: 1286 GDPGDVGGPGPPGASGEPGAPGPPGKRGPSG---------------------HMGREGRE 1324

Query: 541  PDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGER 600
             + GA G PG  GPPG  GP G  G PG++G  GL GI GP G  GL G  G +G  G  
Sbjct: 1325 GEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPL 1384

Query: 601  GPPG----------RGPNGLPGAIGLPGDPGPA-SYGRNGRDGERGPPGVAGIPGVPGP- 648
            GP G          +G  G  G IGL G PG A   G  G  G +GPPG  G PG PGP 
Sbjct: 1385 GPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPI 1444

Query: 649  -----PGPPGLPG 656
                 PGPPG+ G
Sbjct: 1445 GSLGHPGPPGVAG 1457



 Score =  516 bits (1328), Expect = e-146
 Identities = 305/683 (44%), Positives = 358/683 (52%), Gaps = 86/683 (12%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGI------DGDRGPKGPPGPPGPAGEPGKPGAPGKPGTP 79
            G PGE+GPPG PG PG+PG DG       +G  G KG  GPPG AG PG PG  G  GT 
Sbjct: 659  GTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTS 718

Query: 80   GADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----RGIPGPPGPPGTAGLPGELGRV 135
            G  GL G  G  G  G  G KG+ G+ G +G PG    RG  GP GP G AG  GE G  
Sbjct: 719  GNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPP 778

Query: 136  GPVGDPGRRGP---PGPPGPPGPRGTIGFHDGDPLCP--NACPPGRSGYPGLPGMRGHKG 190
            G  G+ G+ G    PG PG PGP+G+IGF    PL P       G++G PGL G RG  G
Sbjct: 779  GSAGEKGKLGVPGLPGYPGRPGPKGSIGF--PGPLGPIGEKGKSGKTGQPGLEGERGPPG 836

Query: 191  AKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPG 250
            ++GE G+PG  G  G +GD G+ G  G  G  G  GL+G  G  G KG  G +G DG PG
Sbjct: 837  SRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPG 896

Query: 251  PQGLPGAPGDQGQRGPPGEAGPKGDRGAE------GARGIPGLPGPKGDTGLPGVDGRDG 304
              G  G  G QGQ GPPG AG  G +G        G RG PG PGP G+ GLPG++GR+ 
Sbjct: 897  HPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGRE- 955

Query: 305  IPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPG 364
                 G KGE G PGP G  G  GL G PG  G  G  G  G  G  G PG +G +G PG
Sbjct: 956  -----GAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPG 1010

Query: 365  QQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRG 424
            ++GP G  G  G  G  GS G +GP G  G  G+ G  G  G  G+PGP G  G  G  G
Sbjct: 1011 ERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAG 1070

Query: 425  VVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEG 484
              GE G KG+ GA G +G  G++G+ G  G PG +G AG+PG PG  G +G RG PG+ G
Sbjct: 1071 PSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFG 1130

Query: 485  PRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSG 544
             +G  G RG  G  G  GL G+ GPPG                     E+       D G
Sbjct: 1131 QKGDDGVRGFVGVIGPPGLQGLPGPPGEK------------------GEVG------DVG 1166

Query: 545  ATGLPGRPGPPGPPGPPGENGFP------------GQMGIRGLPGIKGPPGALGLRGPKG 592
            + G  G PGP GP GP G  G P            G+ G RG  G  GPPGA G+ GPKG
Sbjct: 1167 SMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKG 1226

Query: 593  DLGEKGE------------RGPPGR-------GPNGLPGAIGLPGDPGPASYGRNGRDGE 633
            D+GEKG+            +GPPG        GP GLPG +G PGDPG +  G +G  GE
Sbjct: 1227 DIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVS--GIDGSPGE 1284

Query: 634  RGPPGVAGIPGVPGPPGPPGLPG 656
            +G PG  G PG PG  G PG PG
Sbjct: 1285 KGDPGDVGGPGPPGASGEPGAPG 1307



 Score =  509 bits (1311), Expect = e-144
 Identities = 314/732 (42%), Positives = 357/732 (48%), Gaps = 123/732 (16%)

Query: 22   AAQRGPPGE----------QGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPG 71
            A ++G  GE          +GPPG PGP GV G         P GPPGPPG  G+PG PG
Sbjct: 372  AGEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVG---------PSGPPGPPGFPGDPGPPG 422

Query: 72   APGKPGTPGADGLTGPDGS----PGSIGSKGQKGEP--------------------GVPG 107
              G PG PG DG+ GP G+    P        KG P                    G PG
Sbjct: 423  PAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPG 482

Query: 108  SRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPL 167
              G  GR  PGP G PG  GL GE G  GP G  G +GP GPPG  G  G  G      L
Sbjct: 483  PVGLTGR--PGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGL 540

Query: 168  CPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGL 227
              +  P G  G+ GLPG+ G KG +G+ G      H G+ G  GE GE GA+GPPG  G 
Sbjct: 541  PGDTGPKGDRGFDGLPGLPGEKGQRGDFG------HVGQPGPPGEDGERGAEGPPGPTGQ 594

Query: 228  RGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGL 287
             G  G  G  G +G+ G  G PG  G+ GAPG +G  GPPGE GP G +G  G++G+PG 
Sbjct: 595  AGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGP 654

Query: 288  ------------PGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPG---V 332
                        PG  G  GLPG DG  G PG  G  GE G  GPPG AG  G PG   V
Sbjct: 655  QGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGV 714

Query: 333  PGIPGAKGVAGEKGSTGAPGKPG------QMGNSGKPGQQGPPGEVGPRGPQGLPGSRGE 386
             G  G +G+ GEKG  G  G PG        G+ GKPG  GP GE GP GP+G  G  GE
Sbjct: 715  KGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGE 774

Query: 387  LGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGE--- 443
             GP GS G  GKLG  G PG PG PGP G  G  G  G +GE G  G+ G  G EGE   
Sbjct: 775  EGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGP 834

Query: 444  ---AGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGA 500
                GERG+ G  G PGPKG  G  G PG+    G +GLPG++GP G PGP+G  G QG 
Sbjct: 835  PGSRGERGQPGATGQPGPKGDVGQDGAPGI---PGEKGLPGLQGPPGFPGPKGPPGHQGK 891

Query: 501  TGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPD--SGATGLPGRPGPPGPP 558
             G PG  G  G            +    +      A +  P   +G  G  G  GPPGPP
Sbjct: 892  DGRPGHPGQRGE-----------LGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPP 940

Query: 559  GPPGENGFPGQMGIRGLPGIKGPPGALGLRGP---------------KGDLGEKGERGPP 603
            GPPGE G PG  G  G  G  GPPG LG  GP                G  G KG++GPP
Sbjct: 941  GPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPP 1000

Query: 604  G----------RGPNGLPGAIGLPGDPGP----ASYGRNGRDGERGPPGVAGIPGVPGPP 649
            G          RGP G  G IGLPG  G        G+ G  GERGPPG  G  G+PGP 
Sbjct: 1001 GPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPL 1060

Query: 650  GPPGLPGFCEPA 661
            GP G PG   P+
Sbjct: 1061 GPLGPPGAAGPS 1072



 Score =  502 bits (1292), Expect = e-142
 Identities = 327/820 (39%), Positives = 380/820 (46%), Gaps = 181/820 (22%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGP----------------KGPP----------- 58
            GPPG  G PGPPGP G+PGI GIDG RGP                KGPP           
Sbjct: 410  GPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAV 469

Query: 59   ---------GPPGPAGEPGKPGAPGKPGTPGADG------------LTGPDGSPGSIGSK 97
                     GPPGP G  G+PG  G PG PG  G            L GP G PG +G  
Sbjct: 470  LQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKM 529

Query: 98   GQKGEPGVPGSRGFPG-------RGIPGPPGPPGTAGLPGELGRVG---PVGDPGRRGPP 147
            G+   PG  G+RG PG       RG  G PG PG  G  G+ G VG   P G+ G RG  
Sbjct: 530  GR---PGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAE 586

Query: 148  GPPGP------PGPRGTIGFHDGDPLCPNACP-----PGRSGYPGLPGMRGHKGAKGEIG 196
            GPPGP      PGPRG +G        P   P     PG +G  G PG +G+ G  GE G
Sbjct: 587  GPPGPTGQAGEPGPRGLLG--------PRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPG 638

Query: 197  EPGRQGHKGEEG---DQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQG 253
             PG+QG+ G +G    QG +G  G +GPPG  G+ G+ G  G  G  G  G  GE G QG
Sbjct: 639  PPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQG 698

Query: 254  LPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPG---LPGPKGDTGL---------PGVDG 301
             PG+ G  G  GP G  G  G+RG +G +G  G    PG KGD GL         PG  G
Sbjct: 699  PPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRG 758

Query: 302  RDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSG 361
             DG  G  G  G+ G+ GPPG AG +G  GVPG+PG  G  G KGS G PG  G +G  G
Sbjct: 759  EDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKG 818

Query: 362  KPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKG 421
            K G+ G PG  G RGP   PGSRGE G  G+ G PG  G +G  G PG+PG  GLPG++G
Sbjct: 819  KSGKTGQPGLEGERGP---PGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQG 875

Query: 422  DRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAG---------------NPG 466
              G  G  GP G QG  G  G  G+RGELG  G  GP G AG                 G
Sbjct: 876  PPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERG 935

Query: 467  EPGLRGPEGSRGLPGVEG---------PRGP------------PGPRGVQGEQGATGLPG 505
             PG  GP G +GLPG+EG         P GP            PGP+G  G+ G TGL G
Sbjct: 936  PPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKG 995

Query: 506  VQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENG 565
             +GPPG    +    +               S      G  G  G  G  GPPGP G++G
Sbjct: 996  DKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDG 1055

Query: 566  FPGQMGIRGLPGIKGPPGA------LGLRGPKGDLGEKGERGPPG----RGPNGLPGAIG 615
             PG +G  G PG  GP G       +G  G KG  G+KG+ GPPG    RGP G PG  G
Sbjct: 1056 IPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPG 1115

Query: 616  LPGDPG----PASYGRNGRDGERG------PPGVAGIPG------------------VPG 647
              G  G    P  +G+ G DG RG      PPG+ G+PG                   PG
Sbjct: 1116 ADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPG 1175

Query: 648  PPGP---------PGLPGFCEPASCTMQAGQRAFNKGPDP 678
            P GP         PGLPG         + G+R     P P
Sbjct: 1176 PRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGP 1215



 Score =  499 bits (1285), Expect = e-141
 Identities = 313/727 (43%), Positives = 357/727 (49%), Gaps = 127/727 (17%)

Query: 25   RGPPGEQGPPGPPGPPGVPGIDG---IDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGA 81
            +GPPG  GPPG PGP GV G  G   + G++G KG  G PG  G+ G  G  GKPG PG 
Sbjct: 697  QGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGP 756

Query: 82   DGLTGPDGSPGSIGSKGQKGEPG---------VPGSRGFPGR-------GIPGPPGP--- 122
             G  GP+G  G  G  G++G PG         VPG  G+PGR       G PGP GP   
Sbjct: 757  RGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGE 816

Query: 123  ---PGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGY 179
                G  G PG  G  GP G  G RG PG  G PGP+G +G  DG P  P     G  G 
Sbjct: 817  KGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVG-QDGAPGIP-----GEKGL 870

Query: 180  PGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGE 239
            PGL G  G  G KG  G  G+ G  G  G +GELG  G  GPPG  G+ G  G  G+ G 
Sbjct: 871  PGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGP 930

Query: 240  KGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPG- 298
             G RG  G PGP G  G PG +G+ G  GE GP G  G EG  G+ G PGPKG  G PG 
Sbjct: 931  LGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGP 990

Query: 299  --VDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGS--------- 347
              + G  G PG  G  G PG+ GP G AG  GLPG  G  G  G AG+KGS         
Sbjct: 991  TGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGP 1050

Query: 348  TGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPG---SRGELGPVGSPGLPGKLGSLGS 404
            TG  G PG +G  G PG  GP GE G +G  G PG   S+G+ G  G PG PG  G  G 
Sbjct: 1051 TGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGH 1110

Query: 405  PGLPGLPG------PPGLPGMKGDRGV------VGEPGPKGEQGASGEEGEAGERGELGD 452
            PG PG  G      PPGL G KGD GV      +G PG +G  G  GE+GE G+ G +G 
Sbjct: 1111 PGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGP 1170

Query: 453  IGLPGPKG------SAGNPG------EPGLRGPEGSRG---------LPGVEGPRGPPGP 491
             G PGP+G      S G PG      +PG  G +G RG          PG+ GP+G  G 
Sbjct: 1171 HGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGE 1230

Query: 492  RGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGR 551
            +G  G  GA G PG +GPPG       +                        G TGLPG 
Sbjct: 1231 KGDSGPSGAAGPPGKKGPPGEDGAKGSV------------------------GPTGLPGD 1266

Query: 552  PGPPGPPG------PPGENGFPGQMGIRGLPGIKGPPGALG---LRGPKGDLGEKGERGP 602
             GPPG PG       PGE G PG +G  G PG  G PGA G    RGP G +G +G  G 
Sbjct: 1267 LGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGE 1326

Query: 603  PGR----GPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGV---------PGPP 649
             G     GP+G PG  G  G  GP   GR G +G RG PG  G PG+         PGP 
Sbjct: 1327 KGAKGEPGPDGPPGRTGPMGARGPP--GRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPL 1384

Query: 650  GPPGLPG 656
            GP GLPG
Sbjct: 1385 GPSGLPG 1391



 Score =  473 bits (1218), Expect = e-133
 Identities = 276/597 (46%), Positives = 320/597 (53%), Gaps = 56/597 (9%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 85
            GP GE+GPPGPPGPPG  G+ G++G  G KG  GPPGP G+ G  G  G PG  G     
Sbjct: 929  GPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKG----- 983

Query: 86   GPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRG 145
            GP G PG  G KG KG PG  G+ G PG    GP GP G  GLPG+ G  GPVG  G++G
Sbjct: 984  GP-GDPGPTGLKGDKGPPGPVGANGSPGER--GPLGPAGGIGLPGQSGSEGPVGPAGKKG 1040

Query: 146  PPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKG 205
              G  GPPGP G     DG P      P G  G PG  G  G +G KG++G PG +G KG
Sbjct: 1041 SRGERGPPGPTGK----DGIP-----GPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKG 1091

Query: 206  EEGDQGELGEVGAQGPPG---------AQGLRGITGIVGDKGEKGARGLDGEPGPQGLPG 256
            ++GD G  G+ G +GP G         AQG RG  G+ G KG+ G RG  G  GP GL G
Sbjct: 1092 DKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQG 1151

Query: 257  APGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPG 316
             PG      PPGE G  GD G+ G  G PG  GP+G TG  G  G  G  G PG  GE G
Sbjct: 1152 LPG------PPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKG 1205

Query: 317  KPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRG 376
            + G   DAG  G PG PGIPG KG  GEKG +G  G       +G PG++GPPGE G +G
Sbjct: 1206 ERG---DAGDPGPPGAPGIPGPKGDIGEKGDSGPSGA------AGPPGKKGPPGEDGAKG 1256

Query: 377  PQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPG---PKG 433
              G  G  G+LGP G PG+ G  GS G  G PG  G PG PG  G+ G  G PG   P G
Sbjct: 1257 SVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSG 1316

Query: 434  EQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRG---PPG 490
              G  G EGE G +GE G  G PG  G  G  G PG  GPEG RG+PG  G  G    PG
Sbjct: 1317 HMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPG 1376

Query: 491  PRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPG 550
              G  G  G +GLPG++G  G      HI  + +            + ++ D G  G+ G
Sbjct: 1377 QMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGL------IGPPGEAGEKGDQGLPGVQG 1430

Query: 551  RPGP---PGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG 604
             PGP   PGPPGP G  G PG  G+ G  G KG  G+ G  GP+GD G  G  GPPG
Sbjct: 1431 PPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSKGSPGSMGPRGDTGPAGPPGPPG 1487



 Score =  405 bits (1041), Expect = e-113
 Identities = 258/612 (42%), Positives = 294/612 (48%), Gaps = 66/612 (10%)

Query: 91  PGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPP 150
           PG+ G KG KGEP V       G+   GPPG PG  G+ G  G  GP G PG  GPPGP 
Sbjct: 370 PGA-GEKGAKGEPAVIEK----GQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPA 424

Query: 151 GPPGPRGTIGFHDGDPLCPNACPPGRSG--YPGLPGMRGHKGAKGEIGEPGRQGHKGEEG 208
           G PG  G  G   G P      P   +G  + G P       A+  + +  +   KG  G
Sbjct: 425 GLPGIPGIDGIR-GPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQT-QLSMKGPPG 482

Query: 209 DQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPG 268
             G  G  G  G PG  GL+G  G  G +G +G +G  G PG  G  G PG  G RG PG
Sbjct: 483 PVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPG 542

Query: 269 EAGPKGDRGAEGARGIPGLPGPKGD------TGLPGVDGRDGIPGMPGTKGEPGKPGPPG 322
           + GPKGDRG +G  G+PG  G +GD       G PG DG  G  G PG  G+ G+PGP G
Sbjct: 543 DTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRG 602

Query: 323 ------DAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGP------PG 370
                   G  G PGV GI GA G  G  G  G PG PGQ GN G  G  GP      PG
Sbjct: 603 LLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPG 662

Query: 371 EVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPG 430
           E GP G  G+PG  G  GP+G PG  G  G  G+ G PG  GPPG PG    RGV G  G
Sbjct: 663 EKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPG---PRGVKGTSG 719

Query: 431 PKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPG 490
            +G QG  GE+GE G  G  GD+GL G +G  G PG  G  GPEG +G  G  G  GPPG
Sbjct: 720 NRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPG 779

Query: 491 PRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPG 550
             G +G+ G  GLPG  G PG                                G+ G PG
Sbjct: 780 SAGEKGKLGVPGLPGYPGRPG------------------------------PKGSIGFPG 809

Query: 551 RPGPPGPPGPPGENGFPGQMGIRGLPGIKGP---PGALGLRGPKGDLGEKGERGPPGRGP 607
             GP G  G  G+ G PG  G RG PG +G    PGA G  GPKGD+G+ G  G PG   
Sbjct: 810 PLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGE-- 867

Query: 608 NGLPGAIGLPGDPGPASY-GRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQ 666
            GLPG  G PG PGP    G  G+DG  G PG  G  G  G  GPPG  G   P   T +
Sbjct: 868 KGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGE 927

Query: 667 AGQRAFNKGPDP 678
            G       P P
Sbjct: 928 VGPLGERGPPGP 939



 Score =  368 bits (944), Expect = e-101
 Identities = 220/498 (44%), Positives = 255/498 (51%), Gaps = 64/498 (12%)

Query: 22   AAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPA------GEPGKPGAP-- 73
            A ++G  GE+GPPGP G  G+PG         P GP GPPG A      G+ G  GAP  
Sbjct: 1036 AGKKGSRGERGPPGPTGKDGIPG---------PLGPLGPPGAAGPSGEEGDKGDVGAPGH 1086

Query: 74   ----------GKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGP 122
                      G PG PG  G  G  G PG+ G++G++G PG+ G +G  G RG  G  GP
Sbjct: 1087 KGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGP 1146

Query: 123  PGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGL 182
            PG  GLPG  G  G VGD G  GP G PGP GP+G  G         +   PG  G  G 
Sbjct: 1147 PGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTG---------SEGTPGLPGGVGQ 1197

Query: 183  PGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGA 242
            PG  G KG +G+ G+PG  G  G  G +G++GE G  GP GA G  G  G  G+ G KG+
Sbjct: 1198 PGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGS 1257

Query: 243  RGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGD---RGAEGARGIPGLPGPKGDTGLPGV 299
             G  G PG  G PG PG  G  G PGE G  GD    G  GA G PG PGP G  G  G 
Sbjct: 1258 VGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGH 1317

Query: 300  DGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGN 359
             GR+G  G  G KGEPG  GPPG  G  G  G PG  G +G+       G PG  G+ G 
Sbjct: 1318 MGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGL------RGIPGPVGEPGL 1371

Query: 360  SGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGM 419
             G PGQ GPP   GP GP GLPG +G+ GP G  G  G +G +G PG  G  G  GLPG+
Sbjct: 1372 LGAPGQMGPP---GPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGV 1428

Query: 420  KGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGL 479
            +G  G  G+PGP G  G+ G  G  G  G LG       KGS G+PG  G RG       
Sbjct: 1429 QGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQ------KGSKGSPGSMGPRGD------ 1476

Query: 480  PGVEGPRGPPGPRGVQGE 497
                GP GPPGP G   E
Sbjct: 1477 ---TGPAGPPGPPGAPAE 1491



 Score =  281 bits (719), Expect = 1e-75
 Identities = 187/427 (43%), Positives = 206/427 (48%), Gaps = 65/427 (15%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 85
            GPPG QG PGPPG  G  G  G  G  G  GP GP GP G  G PG PG  G PGA G  
Sbjct: 1145 GPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEK 1204

Query: 86   G---------PDGSPG------SIGSKGQKGEPGV---PGSRGFPG----RGIPGPPGPP 123
            G         P G+PG       IG KG  G  G    PG +G PG    +G  GP G P
Sbjct: 1205 GERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLP 1264

Query: 124  GTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLP 183
            G  G PG+ G  G  G PG +G PG  G PGP G  G             PG  G PG  
Sbjct: 1265 GDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASG------------EPGAPGPPGKR 1312

Query: 184  GMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPP---GAQGLRGITGIVGDKGEK 240
            G  GH G +G  GE G +G  G +G  G  G +GA+GPP   G +GLRGI G VG+ G  
Sbjct: 1313 GPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLL 1372

Query: 241  GARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVD 300
            GA G  G PGP G  G PG +G  GP GE   KG  G  G  G PG  G KGD GLPGV 
Sbjct: 1373 GAPGQMGPPGPLGPSGLPGLKGDTGPKGE---KGHIGLIGLIGPPGEAGEKGDQGLPGVQ 1429

Query: 301  GRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNS 360
                  G PG KG+PG PGP G        G PG PG  G  G+KGS G+PG  G  G++
Sbjct: 1430 ------GPPGPKGDPGPPGPIGSL------GHPGPPGVAGPLGQKGSKGSPGSMGPRGDT 1477

Query: 361  GKPGQQGPPGEVGPRGPQGLPGSRGELG---PVGSPGLPGKLGSLGSPGL--------PG 409
            G  G  GPPG   P    GL   R  +    PV   GL   L SL S  L        PG
Sbjct: 1478 GPAGPPGPPG--APAELHGLRRRRRFVPVPLPVVEGGLEEVLASLTSLSLELEQLRRPPG 1535

Query: 410  LPGPPGL 416
                PGL
Sbjct: 1536 TAERPGL 1542



 Score = 80.1 bits (196), Expect = 6e-15
 Identities = 53/126 (42%), Positives = 60/126 (47%), Gaps = 34/126 (26%)

Query: 7    DRGALGLLLLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGE 66
            ++G +GL+  GL     + G  G+QG PG  GPP            GPKG PGPPGP G 
Sbjct: 1401 EKGHIGLI--GLIGPPGEAGEKGDQGLPGVQGPP------------GPKGDPGPPGPIGS 1446

Query: 67   PGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTA 126
             G PG P         G+ GP G  GS GS         PGS G   RG  GP GPPG  
Sbjct: 1447 LGHPGPP---------GVAGPLGQKGSKGS---------PGSMG--PRGDTGPAGPPGPP 1486

Query: 127  GLPGEL 132
            G P EL
Sbjct: 1487 GAPAEL 1492


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score =  517 bits (1332), Expect = e-146
 Identities = 316/727 (43%), Positives = 360/727 (49%), Gaps = 107/727 (14%)

Query: 24   QRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADG 83
            + G  GE+GPPGP G  G+PG+ G  G +GP+GPPGP G  GE G+PG PG P   G   
Sbjct: 1490 EAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGP-A 1548

Query: 84   LTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGT------------AGLPGE 131
            + GP G  G +G  G +G  GV G RG PG  +PG PGP G             AG PG+
Sbjct: 1549 VAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGD 1608

Query: 132  LGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHD-----GDPLCPNACPPGRSGYPGLPGMR 186
             G  G  GDPGR GPPGP GP G  G +G        GDP  P     G  G  G PG+R
Sbjct: 1609 SGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKA--GERGLRGAPGVR 1666

Query: 187  GHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGI-VGDKGEKGARGL 245
            G  G KG+ G+PG  G  G  G  G  G+ G  GPPG  G    TG    +KGE G RG 
Sbjct: 1667 GPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQ 1726

Query: 246  DGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGI 305
            +G  GP+G PG PG  G+RG  G  GP G +G  G RG  G    KGD G PG+DGR G+
Sbjct: 1727 EGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAG---EKGDRGPPGLDGRSGL 1783

Query: 306  PGMPGT------KGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGN 359
             G PG        G  GK G PG  GL GL G  G+PG  G  G  G  G  GKPG  G 
Sbjct: 1784 DGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGK 1843

Query: 360  SGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGP-----P 414
            +G+PG  G  G  G +G  G  G  G  GP G  G PG LG  G PGLPG  GP     P
Sbjct: 1844 NGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFP 1903

Query: 415  GLPGMKGDRGVVGEPGPKGEQGASGEEGEAGE---------------------------- 446
            G+PG  G +G  GE G KGEQG  GE G  GE                            
Sbjct: 1904 GVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETW 1963

Query: 447  --------------RGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGP------- 485
                          RG  GD G  GP G  G  G PG RG +G RG PG +GP       
Sbjct: 1964 DESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGE 2023

Query: 486  RGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGA 545
            RGPPGP G+ GE G  G+PG+   PGRA       +   R       E     +R + G 
Sbjct: 2024 RGPPGPSGLAGEPGKPGIPGL---PGRAGGVGEAGRPGER------GERGEKGERGEQGR 2074

Query: 546  TGLPGRPGPPGPPGPPGEN--------GFPGQMGIRGLPGIKGPPGALGLRGPKGDLGE- 596
             G PG PG PGPPGPPG          G  G+ G  GL G KG PG+ G +GPKGD G  
Sbjct: 2075 DGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVP 2134

Query: 597  --KGERGPPGRGPNGLPGAIGLPGDPGPAS-YGRNGRDGERGPPGVAGIPGVPGPPGPPG 653
              KG+RG P  GP G  G  GLPG+ G A   G+ G  G RGPPG  G  G PGPPG PG
Sbjct: 2135 GIKGDRGEP--GPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPG 2192

Query: 654  LPGFCEP 660
            L G   P
Sbjct: 2193 LAGPAGP 2199



 Score =  511 bits (1317), Expect = e-145
 Identities = 325/771 (42%), Positives = 384/771 (49%), Gaps = 118/771 (15%)

Query: 20   LCAAQRGPPGEQGPPGPPGPPGVPGI------------DGIDGDRGPKGPPGPPGPAGEP 67
            L   +RGPPG  G  G PG PG+PG+             G  G+RG KG  G  G  G P
Sbjct: 2019 LALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPP 2078

Query: 68   GKPGAPGKPGTP-----------------GADGLTGPDGSPGSIGSKGQKGEPGVPGSRG 110
            G PG PG PG P                 G  GL G  G PGS G +G KG+ GVPG +G
Sbjct: 2079 GLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKG 2138

Query: 111  FPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPN 170
               RG PGP G  G  GLPGE G  GP G PG +GP GPPGP G  G  G      L   
Sbjct: 2139 --DRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGP 2196

Query: 171  ACPPGRSGYPGLP--------GMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPP 222
            A P G SG  G P        G+ G  GA G  G PG  G  G +G  G  G+VG  G P
Sbjct: 2197 AGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKP 2256

Query: 223  GAQGLRGITGIVGDKGEKGARGL---------DGEPGPQGLP-----GAPGDQGQRGPP- 267
            GA G  G +G  GD+G  G  G           GEPGP G P     G PG +G++G P 
Sbjct: 2257 GAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPG 2316

Query: 268  -------GEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGE-----P 315
                   GE G KGDRG  G RG  G  G  G+ G PG DG+ G PG  G KG+     P
Sbjct: 2317 GLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVP 2376

Query: 316  GKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPR 375
            G PGPPG  G++G  G+PG+PGA GV G  G TG  G+ GQ G SG+ G  GPPG  G  
Sbjct: 2377 GSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIP 2436

Query: 376  GPQGLPGSRGELGPVGSPGLPGKLGS--------LGSPGLPGLPGPPGLPGMKGDRGVVG 427
            GP G PG  G +GP G+ GL G  G          G  G PG+ G  G PG +G RG+ G
Sbjct: 2437 GPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTG 2496

Query: 428  EPGPKGEQGASGEEGEAGERGELGD----IGLPGPKGSAGNPGEPGLR------GPEGSR 477
             PG +GE+G  G+ G AG +G+ GD    +G PGP+G+ G+ GE G R      GP G  
Sbjct: 2497 PPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDN 2556

Query: 478  GLPGVEGPRGPPGPR------------GVQGEQGATGLPGVQGPPGR------APTDQHI 519
            G PG +G +G PG +            G QG+ GA G+PG  G PG+            +
Sbjct: 2557 GDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDV 2616

Query: 520  KQVCMRVIQ-EHFAEMAASL--KRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLP 576
              +  R ++ E   + A  L  ++ D G  G PGRPG  G  G  GE G PGQ G  G  
Sbjct: 2617 GFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKE 2676

Query: 577  GIKGPPGALGL---RGPKGDLGEKGERGPPG----RGPNGLPGAIGLPGDPGPAS----Y 625
            G+ GP G  G     GPKGD GEKGERG PG     GP+G  G+ G PG PG        
Sbjct: 2677 GLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPE 2736

Query: 626  GRNGRDGERGPPG--VAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNK 674
            G  G+ GERGPPG  V G PGVPG PG  G  G   PA    + G+ A  +
Sbjct: 2737 GLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTE 2787



 Score =  503 bits (1296), Expect = e-142
 Identities = 311/697 (44%), Positives = 362/697 (51%), Gaps = 122/697 (17%)

Query: 24   QRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADG 83
            Q+G PGE G  G  GPPG PG+ G  G  GP+GPPG     GE G PGA G+PG+PG  G
Sbjct: 1255 QKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAG 1314

Query: 84   LTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGE-LGRVGPVGDPG 142
                  +PG+ G+ G KG PG+PG RG PG    GP GP G  G PG+ +G  GP G PG
Sbjct: 1315 ------NPGTPGAPGLKGSPGLPGPRGDPGE--RGPRGPKGEPGAPGQVIGGEGP-GLPG 1365

Query: 143  RRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPG--MRGHKGAKGEIGEPGR 200
            R+G PGP GPPGPRG +G             PG  G PGLPG  M+G KG +GE G PG 
Sbjct: 1366 RKGDPGPSGPPGPRGPLG------------DPGPRGPPGLPGTAMKGDKGDRGERGPPG- 1412

Query: 201  QGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGD 260
                GE G     GE G  G PG+ G +G  G  G KGEKG    DG PG  G PG+PG+
Sbjct: 1413 ---PGEGGIAP--GEPGLPGLPGSPGPQGPVGPPGKKGEKG-DSEDGAPGLPGQPGSPGE 1466

Query: 261  QGQRGPPGEAGPKGDR------GAEGARGIPGLPGPKGDTGLPGVDGR------DGIPGM 308
            QG RGPPG  GPKGDR      G  G +G  G PGP G  GLPGV GR      +G PG 
Sbjct: 1467 QGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGP 1526

Query: 309  PGTKGEPGKPGPPGD--------------------AGLQGLPGV-----------PGIPG 337
             G +GE G+PG PGD                    AG +G  GV           PG PG
Sbjct: 1527 TGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPG 1586

Query: 338  AKGVAGEKGSTGAPGKPGQMGNSGKPGQQ------GPPGEVGPRGPQGLPGSRGELGPVG 391
             KG  G++G  G  G+ G  G+SG PG++      GPPG VGPRG  G  G +G+ GP G
Sbjct: 1587 PKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPG 1646

Query: 392  SPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELG 451
             PGLPGK G  G  G PG+ GP G  G +GD G  G  G  G  G  G+ GE G  G  G
Sbjct: 1647 DPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPG 1706

Query: 452  DIGLPGP----KGSAGNPGEPGLRGPEGSRGLP------GVEGPRGPPGPRGVQGEQGAT 501
             +   GP    KG  G+ G+ G RGP+G  GLP      G+EG RGPPGP+G  G +G  
Sbjct: 1707 RLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPA 1766

Query: 502  GLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPP 561
            G  G +GPPG                                G +GL G+PG  GP GP 
Sbjct: 1767 GEKGDRGPPGL------------------------------DGRSGLDGKPGAAGPSGPN 1796

Query: 562  GENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDP 620
            G  G  G  G  GLPG++G  G  G  GP G  G+ GE G PG  G NG PG  G  G  
Sbjct: 1797 GAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRK 1856

Query: 621  G-PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
            G     G +GR+G  GP G  G PG+ GP GPPGLPG
Sbjct: 1857 GEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPG 1893



 Score =  492 bits (1266), Expect = e-139
 Identities = 327/809 (40%), Positives = 382/809 (47%), Gaps = 176/809 (21%)

Query: 17   GLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEP--------- 67
            G      +RG PG  G PG PG  G PG  G  G    KG PG PGP G+P         
Sbjct: 1290 GSATAKGERGFPGADGRPGSPGRAGNPGTPGAPG---LKGSPGLPGPRGDPGERGPRGPK 1346

Query: 68   GKPGAPGK------PGTPGADGLTGPDGSP---GSIGSKGQKGEPGVPGS--RGFPG--- 113
            G+PGAPG+      PG PG  G  GP G P   G +G  G +G PG+PG+  +G  G   
Sbjct: 1347 GEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRG 1406

Query: 114  -RGIPGP------PGPPGTAGLPGELGRVGPVGDPGRR---------------------- 144
             RG PGP      PG PG  GLPG  G  GPVG PG++                      
Sbjct: 1407 ERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGE 1466

Query: 145  -GPPGPPGPPGPRGTIGFHDGDPLCP-----NACPPGRSGYPGLPGMRGHKGAKGEIGEP 198
             GP GPPG  GP+G  GF    PL          PPG +G  GLPG+ G  GAKG  G P
Sbjct: 1467 QGPRGPPGAIGPKGDRGF--PGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPP 1524

Query: 199  ---GRQGHKGE-----------------EGDQGELGEVGAQGPPGAQGLRGITGIV---- 234
               GRQG KGE                 +G++G++G  G +G  G QG RG  G+V    
Sbjct: 1525 GPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGD 1584

Query: 235  -------GDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPK------GDRGAEGA 281
                   GD+G  G  G  G PG  G PG  GD G+ GPPG  GP+      G++G EG 
Sbjct: 1585 PGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGP 1644

Query: 282  RGIPGLP------------------GPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGD 323
             G PGLP                  G KGD G PG DGR+G PG  G KG+ G+PGPPG 
Sbjct: 1645 PGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGP 1704

Query: 324  AGL-------------------------QGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMG 358
             G                          +G PG+PG PG +G+ G +G  G  G PG  G
Sbjct: 1705 PGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRG 1764

Query: 359  NSGKPGQQGPPGEVGPRGPQGLPGSRGELGP------VGSPGLPGKLGSLGSPGLPGLPG 412
             +G+ G +GPPG  G  G  G PG+ G  GP       G PG  G  G  G  GLPG  G
Sbjct: 1765 PAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSG 1824

Query: 413  PPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRG 472
            PPGLPG  G+ G  G  G  GE G  GE+G  GE+G+ G  G  G  G  G  G PG+ G
Sbjct: 1825 PPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILG 1884

Query: 473  PEGSRGLPGVEGP-----------RGPPGPRGVQGEQGATGLP---GVQGPPGRAPTDQH 518
            P+G  GLPG  GP            GP G RG  G +G  GLP   G++G PG  P    
Sbjct: 1885 PQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDR 1944

Query: 519  ------IKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGI 572
                  IK   +R I E + E + S         G  G  G  GPPG  G  GFPG+ G+
Sbjct: 1945 LLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGL 2004

Query: 573  ---RGLPGIKGPPG-ALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPG-PASYGR 627
               RG PG +GPPG ALG RGP G  G  GE G P  G  GLPG  G  G+ G P   G 
Sbjct: 2005 KGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKP--GIPGLPGRAGGVGEAGRPGERGE 2062

Query: 628  NGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
             G  GERG  G  G PG+PG PGPPG PG
Sbjct: 2063 RGEKGERGEQGRDGPPGLPGTPGPPGPPG 2091



 Score =  486 bits (1252), Expect = e-137
 Identities = 315/803 (39%), Positives = 371/803 (46%), Gaps = 189/803 (23%)

Query: 22   AAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKP---GT 78
            A ++G PG++G  GP GP G PG+ G  G+RG +G  GPPGP G+PG  G  G+    G 
Sbjct: 1715 AREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGP 1774

Query: 79   PGADGLTGPDGSPGSIGSKGQK---GEPGVPGSRGFPG----RGIPGPPGPPGTAGL--- 128
            PG DG +G DG PG+ G  G     G+ G PG  G PG    +G+PGP GPPG  G    
Sbjct: 1775 PGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGE 1834

Query: 129  ---------------PGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGF--HDGDPLCPNA 171
                           PGE GR G  GD G  G  G  GP G RG  G     G P  P  
Sbjct: 1835 DGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGP 1894

Query: 172  CPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEV--------------- 216
              P   G+PG+PG  G KG +GE G  G QG  GE G +GE G V               
Sbjct: 1895 VGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKAS 1954

Query: 217  ------------------------------GAQGPPGAQGLRGITG-------------- 232
                                          G QGPPG +G  G  G              
Sbjct: 1955 ALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQ 2014

Query: 233  -----IVGDKGEKGARGLDGEPGPQGLPGAP---------GDQGQRGPPGEAGPKGDRGA 278
                  +G++G  G  GL GEPG  G+PG P         G  G+RG  GE G +G++G 
Sbjct: 2015 GPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGR 2074

Query: 279  EGARGIPGLPGPKGDTGL--------PGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLP 330
            +G  G+PG PGP G  G         PG+ G  G PG+ G KGEPG  G  G  G +G+P
Sbjct: 2075 DGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVP 2134

Query: 331  GV---------------PGIPGAKGVAGEKGSTGAP---GKPGQMGNSGKPGQQGPPGEV 372
            G+               PG+PG +G+AG +G  G     G PG +G  G PG  G PG  
Sbjct: 2135 GIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLA 2194

Query: 373  GPRGPQGLPGSRGELGPVGSP--GLPGKLGSLGSPGLP---GLPGPPGLPGMKGDRGVVG 427
            GP GPQG  G +GE G  G P  GL G  G++G PG P   GL GP G PG+ G  G  G
Sbjct: 2195 GPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETG 2254

Query: 428  EPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGE-----------PGLRGPEGS 476
            +PG  G  GASG++G+ G  G  G  GLPGP G  G PG            PG +G +G+
Sbjct: 2255 KPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGA 2314

Query: 477  R--------GLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGR--APTDQHIKQVCMRV 526
                     G PG +G RG PGPRG +GE G  G PG  G  G+  AP  +  K      
Sbjct: 2315 PGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFK------ 2368

Query: 527  IQEHFAEMAASLKRPDSGATGLPGRPGPPGP------------PGPPGENGFPGQMGIRG 574
                           D G  G+PG PGPPGP            PG PG  GFPGQ G RG
Sbjct: 2369 --------------GDPG-VGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRG 2413

Query: 575  LPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGPASYGRNGRDGE 633
              G  GP G  GL GP G  G  G  GPPG  G  G PGA GL GD G    G  G  GE
Sbjct: 2414 EMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGE 2473

Query: 634  RGPPGVAGIPGVPGPPGPPGLPG 656
            RG PG+ G  G PG  GP GL G
Sbjct: 2474 RGEPGIRGEDGRPGQEGPRGLTG 2496



 Score =  484 bits (1247), Expect = e-137
 Identities = 337/840 (40%), Positives = 385/840 (45%), Gaps = 180/840 (21%)

Query: 7    DRGALGLLLLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGE 66
            DRG +GL   G        GPPGE+G PG PGPPG  G  G DG+ G KG  GPPG  G 
Sbjct: 1593 DRGPIGLT--GRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGL 1650

Query: 67   PGKPGAPGKPGTPGADGLTGP------------DGSPGSIGSKGQKGEPGVPG------- 107
            PGK G  G  G PG  G  G             +GSPGS G KG +GEPG PG       
Sbjct: 1651 PGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVD 1710

Query: 108  ------SRGFPG----------RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPG 151
                   +G PG          +G PG PG PG  G+ G  G  GP GDPG RGP G  G
Sbjct: 1711 TGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKG 1770

Query: 152  PPGPRGTIGFH--DGDPLCPNACPP----GRSGYPG---LPGMRGHKGAKGEIGEPGRQG 202
              GP G  G    DG P       P    G++G PG   LPG+RG +G  G  G PG  G
Sbjct: 1771 DRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPG 1830

Query: 203  HKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQG 262
              GE+G  G  G+ G  G PG  G +G      +KG+ GA G +G  GP+G  GAPG  G
Sbjct: 1831 KPGEDGKPGLNGKNGEPGDPGEDGRKG------EKGDSGASGREGRDGPKGERGAPGILG 1884

Query: 263  QRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPG------ 316
             +GPPG  GP G  G +G  G+PG  GPKGD G  G  G  G+PG  G +GEPG      
Sbjct: 1885 PQGPPGLPGPVGPPG-QGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVD 1943

Query: 317  ---------------------------------KPGPPGDAGLQGLPGVPG---IPGAKG 340
                                             + GP GD+G QG PG  G    PG +G
Sbjct: 1944 RLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERG 2003

Query: 341  VAGEKGSTGAPGKPG-QMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKL 399
            + G++G  G  G PG  +G  G PG  G  GE G  G  GLPG  G +G  G PG  G+ 
Sbjct: 2004 LKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGER 2063

Query: 400  GSLGS---------PGLPGLPGPPGLPGMK-----------GDRGVVGEPGPKGEQGASG 439
            G  G          PGLPG PGPPG PG K           G++G  G  G KGE G++G
Sbjct: 2064 GEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNG 2123

Query: 440  EEGEAGERGE---LGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGP----- 491
            ++G  G+RG     GD G PGP+G  GNPG PG RG  G  G PG++GPRGPPGP     
Sbjct: 2124 DQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHG 2183

Query: 492  -------------RGVQGEQGATGLPGVQGPPGRAPTDQHIK------------------ 520
                          G QG  G  G PG  GPPGR  T                       
Sbjct: 2184 DPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGS 2243

Query: 521  -----QVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGP---PGENGFPGQMGI 572
                 QV             AS K  D G+ G+PG PG PGP GP   PG  G PGQ  +
Sbjct: 2244 PGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQ-AV 2302

Query: 573  RGLPGIKGPPGALGLRGPKGDL----GEKGERGPPG-RGPNGLPGAIGLPGDPGP-ASYG 626
             GLPG KG  GA G  G  GDL    G KG+RG PG RG  G  G  G PGDPG     G
Sbjct: 2303 VGLPGAKGEKGAPG--GLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKG 2360

Query: 627  RNGRDGERGPPGVA--------GIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGPDP 678
              G  G +G PGV         G PGV G  G PGLPG         Q G R     P P
Sbjct: 2361 APGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGP 2420



 Score =  484 bits (1246), Expect = e-136
 Identities = 306/720 (42%), Positives = 354/720 (49%), Gaps = 120/720 (16%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGT--PGADG 83
            G PGE G  G  G  G  G +G DG +G +G PG  GP G PG PG  G PG   PG  G
Sbjct: 1848 GDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPG 1907

Query: 84   LTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRG---------------------------- 115
             TGP G  G  GSKG++G PG  G RG PG                              
Sbjct: 1908 GTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESS 1967

Query: 116  ---IPGPP---GPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCP 169
               +P P    GP G +G  G  G+ GP+G PG RG  G  G PGP+G  G   G+   P
Sbjct: 1968 GSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPP 2027

Query: 170  NACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRG 229
               P G +G PG PG+ G  G  G +GE GR G +GE G++GE GE G  GPPG  G  G
Sbjct: 2028 G--PSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPG 2085

Query: 230  ITGIVGDKG--EKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGL 287
              G  G K   ++   GL GE GP GL GA G+ G  G   + GPKGDRG  G +G  G 
Sbjct: 2086 PPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNG---DQGPKGDRGVPGIKGDRGE 2142

Query: 288  PGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGS 347
            PGP+G  G PG+ G  G+ G  G  G  G  GPPG  G  G PG PG PG  G AG +G 
Sbjct: 2143 PGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGP 2202

Query: 348  TGAPGKPGQMGNSGK-----------PGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLP 396
            +G  G+PG+ G  G+           PG  GP G VGP+G  GLPG  GE G  G+PG  
Sbjct: 2203 SGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRD 2262

Query: 397  GKLGSLGSPGLPGLPGPPGLPGMKGDRG-----------VVGEPGPKGEQGA-SGEEGE- 443
            G  G  G  G PG+PG PGLPG  G +G           VVG PG KGE+GA  G  G+ 
Sbjct: 2263 GASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDL 2322

Query: 444  AGERGELGDIGLPGP---KGSAGNPGEPGLRGPEGSRGLP-----------GVEGPRGPP 489
             GE G  GD GLPGP   KG AG  GEPG  G +G +G P           GV G  GPP
Sbjct: 2323 VGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPP 2382

Query: 490  GPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLP 549
            GP GV+G+ G  GLPG  G  G                           +    G  G P
Sbjct: 2383 GPPGVKGDLGLPGLPGAPGVVGFPG------------------------QTGPRGEMGQP 2418

Query: 550  GRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGD-----LGEKGERGPPG 604
            G  G  G  GPPG  G PG +G  G PG  GPPGA GL+G KGD      G +GERG PG
Sbjct: 2419 GPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPG 2478

Query: 605  -RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPG-------VPGPPGPPGLPG 656
             RG +G PG  G  G  GP   G  G  GE+G  G AG+ G       + GPPGP G  G
Sbjct: 2479 IRGEDGRPGQEGPRGLTGPP--GSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKG 2536



 Score =  454 bits (1169), Expect = e-128
 Identities = 279/642 (43%), Positives = 326/642 (50%), Gaps = 84/642 (13%)

Query: 17   GLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKP 76
            GL   A  +GP G +G PG  GPPG     G+ G  G  G PGPPGP+G  G  G+PG P
Sbjct: 2192 GLAGPAGPQGPSGLKGEPGETGPPG----RGLTGPTGAVGLPGPPGPSGLVGPQGSPGLP 2247

Query: 77   GTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----RGIPGPPGPPGTA--GLPG 130
            G  G  G  G  G  G+ G  G +G PGVPGS G PG    +G PGP G PG A  GLPG
Sbjct: 2248 GQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPG 2307

Query: 131  ELGRVGP--------VGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGL 182
              G  G         VG+PG +G  G PGP G +G  G   G+P       PG  G  G 
Sbjct: 2308 AKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAG-RAGEP-----GDPGEDGQKGA 2361

Query: 183  PGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGA 242
            PG +G KG  G +G PG  G  G  G +G+LG  G  G PG  G  G TG  G+ G+ G 
Sbjct: 2362 PGPKGFKGDPG-VGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGP 2420

Query: 243  RGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIP--GLPGPKGDTGLPGVD 300
             G  G  GP G  G PG  G  GPPG  GP G  G +G +G P  GLPGP+G+ G PG+ 
Sbjct: 2421 SGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIR 2480

Query: 301  GRDGIPGM---------PGTKGEPGKPGPPGDAGLQG-------LPGVPGIPGAKGVAGE 344
            G DG PG          PG++GE G+ G  G AGL+G       + G PG  GAKG  GE
Sbjct: 2481 GEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGE 2540

Query: 345  KGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSP---GLPGKLGS 401
            +G  G  G  G  G++G PG +G  GE G +G  GLPG RG LGP G P   G+PG  GS
Sbjct: 2541 RGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGS 2600

Query: 402  LGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGS 461
             G  G+PG+ G  G  G  G RG+ GE G KG  G  GE+G+ GE G  G  GL G KG 
Sbjct: 2601 PGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGE 2660

Query: 462  AGNPGEPGLRGPEGSRGLPGVEGPR---GPPGPRGVQGEQGATGLPGVQGPPGRAPTDQH 518
             G PG PG  G  G  GL G +G R   G PGP+G QGE+G  G PG+ G PG       
Sbjct: 2661 MGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPG------- 2713

Query: 519  IKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGI 578
                                    SG  G  G PGPPG  GP G  G  GQ G RG PG 
Sbjct: 2714 -----------------------PSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGE 2750

Query: 579  KGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGD 619
            +     +G  G  G  GE+GE+G PG  GP G  G   L  D
Sbjct: 2751 R----VVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTED 2788



 Score =  427 bits (1099), Expect = e-119
 Identities = 273/623 (43%), Positives = 313/623 (50%), Gaps = 108/623 (17%)

Query: 97   KGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPR 156
            KGQKGEPG  G RG          GPPG  GLPG  G  GP          GPPG    +
Sbjct: 1253 KGQKGEPGEMGLRG--------QVGPPGDPGLPGRTGAPGP---------QGPPGSATAK 1295

Query: 157  GTIGF--HDGDPLCP-NACPPGRSGYPGL------------PGMRGHKGAKGEIGE---- 197
            G  GF   DG P  P  A  PG  G PGL            PG RG +G KGE G     
Sbjct: 1296 GERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQV 1355

Query: 198  --------PGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARG----- 244
                    PGR+G  G  G  G  G +G  GP G  GL G T + GDKG++G RG     
Sbjct: 1356 IGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPG-TAMKGDKGDRGERGPPGPG 1414

Query: 245  ----LDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLP------GPKGDT 294
                  GEPG  GLPG+PG QG  GPPG+ G KGD   +GA G+PG P      GP+G  
Sbjct: 1415 EGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGD-SEDGAPGLPGQPGSPGEQGPRGPP 1473

Query: 295  GLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKP 354
            G  G  G  G PG  G  GE G+ GPPG AG +GLPGV G PGAKG  G  G TG  G+ 
Sbjct: 1474 GAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEK 1533

Query: 355  GQMGNSGKP--------GQQGPPGEVGPRGPQGLPGSRGELGP-----VGSPGLPGKLGS 401
            G+ G  G P        G +G  G+VGP GP+G  G +GE GP      G PG  G  G 
Sbjct: 1534 GEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGD 1593

Query: 402  LGSPGLPGLPGPP---GLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGP 458
             G  GL G  GPP   G PG KGD G  G PGP G +G  GE GE G+ G  GD GLPG 
Sbjct: 1594 RGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGK 1653

Query: 459  KGSAGNPGEPGLRGP---EGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPT 515
             G  G  G PG+RGP   +G +G PG +G  G PG  G +G++G    PG  GPPGR   
Sbjct: 1654 AGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGE---PGPPGPPGRLVD 1710

Query: 516  DQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGL 575
                                     P +   G PG  G  GP GP G+ G PG  G RG+
Sbjct: 1711 -----------------------TGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGI 1747

Query: 576  PGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGP-ASYGRNGRDGE 633
             G +GPPG  G  G +G  GEKG+RGPPG  G +GL G  G  G  GP  + G+ G  G 
Sbjct: 1748 EGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGR 1807

Query: 634  RGPPGVAGIPGVPGPPGPPGLPG 656
             G PG+ G  G+PGP GPPGLPG
Sbjct: 1808 DGLPGLRGEQGLPGPSGPPGLPG 1830



 Score =  414 bits (1065), Expect = e-115
 Identities = 267/622 (42%), Positives = 310/622 (49%), Gaps = 117/622 (18%)

Query: 25   RGPPGEQGPPG-----PPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGK---- 75
            +G PGE GPPG     P G  G+PG  G  G  GP+G PG PG  GE GKPGAPG+    
Sbjct: 2206 KGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGAS 2265

Query: 76   -----------PGTPGADGLTGPDGSPGSIGSKGQK--GEPGVPGSRGFPG--------- 113
                       PG+PG  G  GP G PG  G+ GQ   G PG  G +G PG         
Sbjct: 2266 GKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGE 2325

Query: 114  ------RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGP--------------PGPPGPP 153
                  RG+PGP G  G AG  GE G  G  G  G  GP              PGPPGPP
Sbjct: 2326 PGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPP 2385

Query: 154  GPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGEL 213
            G +G +G     P  P A  PG  G+PG  G RG  G  G  GE G  G  G EG  G L
Sbjct: 2386 GVKGDLGL----PGLPGA--PGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPL 2439

Query: 214  GEVG---AQGPPGAQGLRG--------ITGIVGDKGEKGARGLDGEPG---PQGLPGAPG 259
            G  G   + GPPGA GL+G        + G  G++GE G RG DG PG   P+GL G PG
Sbjct: 2440 GPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPG 2499

Query: 260  DQGQRGPPGE---AGPKGDRGAEGA-RGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEP 315
             +G+RG  G+   AG KGD+G      G PG  G KGD G  G  G DG  G  G  G+P
Sbjct: 2500 SRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDP 2559

Query: 316  GKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPR 375
            G  G  G+ G +G  G+PG+ G  G  G+ G+ G PG PG  G  G PG +G  G+VG  
Sbjct: 2560 GDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFM 2619

Query: 376  GPQGLPGSRG---------------ELGPVGSPGLPGKLGSLGSPGLPG---LPGPPGLP 417
            GP+GL G RG               E GP G PGL G  G +G PG+PG    PG  GL 
Sbjct: 2620 GPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLI 2679

Query: 418  GMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPK---GSAGNPGEPGLRGPE 474
            G KGDRG  G+PGPKG+Q      GE GERG  G  G PGP    GSAG PG PG  GP 
Sbjct: 2680 GPKGDRGFDGQPGPKGDQ------GEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPR 2733

Query: 475  GSRGLPGVEGPRGPPGPR--------GVQGEQGATGLPGVQGPPGR----APTDQHIKQV 522
            G  GL G +G RGPPG R        G  GE+G  G PG  GP G     A T+  I+  
Sbjct: 2734 GPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTEDDIRGF 2793

Query: 523  CMRVIQEHFA---EMAASLKRP 541
              + + +H A   +  AS  RP
Sbjct: 2794 VRQEMSQHCACQGQFIASGSRP 2815



 Score =  357 bits (917), Expect = 2e-98
 Identities = 216/515 (41%), Positives = 261/515 (50%), Gaps = 59/515 (11%)

Query: 7    DRGALGLL---LLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGP--------- 54
            ++GA G L   L+G       RG PG +G  G  G  G PG  G DG +G          
Sbjct: 2311 EKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGD 2370

Query: 55   --------KGPPGPPGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVP 106
                     GPPGPPG  G+ G PG PG PG  G  G TGP G  G  G  G++G  G P
Sbjct: 2371 PGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPP 2430

Query: 107  GSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDP 166
            G  G PG    GPPGPPG+ G PG  G  G  GDPG     G PGP G RG  G    D 
Sbjct: 2431 GREGIPGP--LGPPGPPGSVGPPGASGLKGDKGDPG----VGLPGPRGERGEPGIRGEDG 2484

Query: 167  LCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQG 226
                   PG+ G  GL G  G +G +GE G+ G  G KG++GD   +      GPPG +G
Sbjct: 2485 ------RPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVI-----LGPPGPRG 2533

Query: 227  LRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPG 286
             +      GD GE+G RGLDG+ GP+G  G PGD+G +G PG+ G  G  G  G  G  G
Sbjct: 2534 AK------GDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQG 2587

Query: 287  LPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKG 346
             PG  G  G PG  G+DG+PG+ G KG+ G  GP    GL+G  GV G  G  G  G+KG
Sbjct: 2588 QPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGP---RGLKGERGVKGACGLDGEKGDKG 2644

Query: 347  STGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPG 406
              G PG+PG  G+ G+ G+ G PG+ G  G +GL G +G+ G  G PG  G  G  G  G
Sbjct: 2645 EAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERG 2704

Query: 407  LPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPG 466
             PG+ G PG  G  G  G  G PG  G +G  G +G+ GERG       P  +   G PG
Sbjct: 2705 TPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERG-------PPGERVVGAPG 2757

Query: 467  EPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGAT 501
             PG  G  G +G P      GP GPRG +GE   T
Sbjct: 2758 VPGAPGERGEQGRP------GPAGPRGEKGEAALT 2786



 Score =  283 bits (724), Expect = 4e-76
 Identities = 181/431 (41%), Positives = 209/431 (48%), Gaps = 64/431 (14%)

Query: 272  PKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGT---KGEPGKPGPPGDAGLQG 328
            PKG +G  G  G+ G  GP GD GLPG  G  G  G PG+   KGE G PG  G  G  G
Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPG 1311

Query: 329  LPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEV-GPRGPQGLPGSRGEL 387
              G PG PGA G+ G  G  G  G PG+ G  G  G+ G PG+V G  GP GLPG +G+ 
Sbjct: 1312 RAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGP-GLPGRKGDP 1370

Query: 388  GPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGP------KGEQGASGEE 441
            GP G PG  G LG  G  G PGLPG   + G KGDRG  G PGP       GE G  G  
Sbjct: 1371 GPSGPPGPRGPLGDPGPRGPPGLPGT-AMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLP 1429

Query: 442  GEAGERGELGDIGLPGPKGSA-----GNPGEPGLRGPEGSRGLPGVEGPRGP---PGPRG 493
            G  G +G +G  G  G KG +     G PG+PG  G +G RG PG  GP+G    PGP G
Sbjct: 1430 GSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLG 1489

Query: 494  VQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPG 553
              GE+G  G PG  G  G                                G  G PG  G
Sbjct: 1490 EAGEKGERGPPGPAGSRGLP------------------------------GVAGRPGAKG 1519

Query: 554  PPGPPGPPGENGFPGQMGIRGLPGIKGPP--------GALGLRGPKGDLGEKGERGPPGR 605
            P GPPGP G  G  G+ G  G P + GP         G +G  GP+G  G +GERGPPG 
Sbjct: 1520 PEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGL 1579

Query: 606  GPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTM 665
               G PG  G PGD GP      G  G  GPPG +G PG  G PG PG PG   P     
Sbjct: 1580 VLPGDPGPKGDPGDRGPI-----GLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDG 1634

Query: 666  QAGQRAFNKGP 676
            + G++  ++GP
Sbjct: 1635 EVGEKG-DEGP 1644


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score =  516 bits (1328), Expect = e-146
 Identities = 309/699 (44%), Positives = 359/699 (51%), Gaps = 100/699 (14%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 85
            GPPG+QG PG  G PG  G  G  G++GP+G PG PG  G  G PG PGK G PG  G  
Sbjct: 560  GPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQ 619

Query: 86   GPDGSPGSIGSKGQKGEPGVPGSRG------------FPG-RGIPGPPGPPGTAGLPGEL 132
            GP G  G +G  G +G  GV G RG            FPG +G  G  G  G  G+PG  
Sbjct: 620  GPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSR 679

Query: 133  GRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPN----ACPPGRSGYPGLPGMRGH 188
            G  GP G  GR GP G PGPPG  G  G   G P  P       P G  G+PG PG  G 
Sbjct: 680  GEDGPEGPKGRTGPTGDPGPPGLMGEKG-KLGVPGLPGYPGRQGPKGSLGFPGFPGASGE 738

Query: 189  KGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGL------------RGITGIVGD 236
            KGA+G  G+ G +G +G  G +G+ G  GA G  GA+G             RG+ G  G 
Sbjct: 739  KGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGP 798

Query: 237  KGEKGARGLDGEPGPQGLPGAPGDQGQ---------RGPPGEAGPKG---DRGAEGARGI 284
             G  G +G  G PG  GLPG PG +G+          GPPG  GP+G   + G  G RG 
Sbjct: 799  NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 858

Query: 285  PGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGL---QGLPGVPGIPGAKGV 341
            PG PGP G+ GLPG  G++G  G PG  G PGK GP G  G    +GLPG  G PG KG 
Sbjct: 859  PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 918

Query: 342  AGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGS 401
             G  G  G  G PG+ G +G  G  GPPG  GP+GP G  G +G  G  G  G  G+ G 
Sbjct: 919  EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGV 978

Query: 402  LGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGS 461
             G  GLPG  GPPG+ G  GD+G VG+PG KG +G  GE G  G  G +G +G P   G+
Sbjct: 979  QGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQP---GA 1035

Query: 462  AGNPGEPGLRGPEGSRGLPGVEGPR---GPPGPRGVQ------GEQGATGLPGVQGPPG- 511
            AG  GEPG RGP+G  G  G EG R   GPPGP G+Q      GE+G TG  G  GPPG 
Sbjct: 1036 AGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGP 1095

Query: 512  ---RAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPG 568
               R P                            +GA G  G PG  G  GPPGE G PG
Sbjct: 1096 PGPRGPAG-------------------------PNGADGPQGPPGGVGNLGPPGEKGEPG 1130

Query: 569  QM---GIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-------RGPNGLPGAIGLPG 618
            +    GI+G PG+KGP G    RG KG+ G+ GE GPPG        GP G PG +G PG
Sbjct: 1131 ESGSPGIQGEPGVKGPRGE---RGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPG 1187

Query: 619  DPG-PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
            DPG P   G  G+DG +G  G  G PG PG PGP G  G
Sbjct: 1188 DPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENG 1226



 Score =  510 bits (1314), Expect = e-144
 Identities = 308/735 (41%), Positives = 359/735 (48%), Gaps = 126/735 (17%)

Query: 23   AQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGAD 82
            A RGPPG  G  G PGP G PG  G+ G+ G  GP GP GP G  G PG  G+ G  GAD
Sbjct: 398  ALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGAD 457

Query: 83   GLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----RGIPGPPGPPGTAGLPGEL------ 132
            G  G  G PG  G +G  G PG+PG +G  G    +G+PGPPG  G  G  GE+      
Sbjct: 458  GARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLP 517

Query: 133  GRVGPVGDPGRRGPPGPPGPP---------GPRGTIGFHDGDPLCPNACPPGRSGYPGLP 183
            G  GP G  G +GPPG PGPP         GP+G++G   G+P      PPG+ G PG  
Sbjct: 518  GESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLG-PQGEP-----GPPGQQGTPGTQ 571

Query: 184  GMRGHKGAKGEIGEPGRQ---------------GHKGEEGDQGELGEVGAQGPPGAQGLR 228
            G+ G +GA G  GE G Q               GH G+EG  G  G  G  GP G  G  
Sbjct: 572  GLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYP 631

Query: 229  GITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLP 288
            G  G+ G  G +G +G  GE G  G PG  GD G +G  GE G  G RG +G  G  G  
Sbjct: 632  GPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRT 691

Query: 289  GPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVA------ 342
            GP GD G PG+ G  G  G+PG  G PG+ GP G  G  G PG  G  GA+G++      
Sbjct: 692  GPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPR 751

Query: 343  ---------GEKGSTGAPGKPGQMGNSGKPGQQGPPGE---VGPRGPQGLPGSRGELGPV 390
                     G++G  GA GK G  G SG  G  GPPGE    GP+GP G PG +G  GP 
Sbjct: 752  GERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPP 811

Query: 391  GSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGEL 450
            G  GLPG  G  G  G  G  GPPG PG+ G +G  GE GP GE+G  G  G  GE+G  
Sbjct: 812  GKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLP 871

Query: 451  GDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPP 510
            G  G  G KG  G PG PG  GP G RG PG  G  G  G  G++G +G +G PG  G P
Sbjct: 872  GTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSP 931

Query: 511  GRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQ- 569
            G                     E  A+      G  G PGRPGP GPPG  GE G PG+ 
Sbjct: 932  G---------------------ERGAA---GSGGPIGPPGRPGPQGPPGAAGEKGVPGEK 967

Query: 570  -----------MGIRGLPGIKGPPGALGLRGPKGDLGE---------KGERGPPGR---- 605
                        G  GLPG  GPPG  G  G KG++G+         KGE GPPG     
Sbjct: 968  GPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPI 1027

Query: 606  GPNGLPGAIGLPGDPG----PASYGRNGRDGER---GPPGVAGIPGVPGPP--------- 649
            GP G PGA G  G+PG       +G  G +G R   GPPG  G+ G+PGP          
Sbjct: 1028 GPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDV 1087

Query: 650  ---GPPGLPGFCEPA 661
               GPPG PG   PA
Sbjct: 1088 GPMGPPGPPGPRGPA 1102



 Score =  505 bits (1300), Expect = e-143
 Identities = 299/679 (44%), Positives = 344/679 (50%), Gaps = 68/679 (10%)

Query: 25   RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGL 84
            +G  G  GP GPPG  G+PG  G +G  GPKGPPGPPG   + G PG PG+ G  G  G 
Sbjct: 775  KGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPG---KDGLPGHPGQRGEVGFQGK 831

Query: 85   TGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRR 144
            TGP G PG +G +G  GE G  G RG PG     PPGPPG  GLPG  G+ G  GDPG  
Sbjct: 832  TGPPGPPGVVGPQGAAGETGPMGERGHPG-----PPGPPGEQGLPGTAGKEGTKGDPG-- 884

Query: 145  GPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHK 204
             PPG PG  GP G  GF     L      PG +G PGL G  G  G  G  G PG +G  
Sbjct: 885  -PPGAPGKDGPAGLRGFPGERGL------PGTAGGPGLKGNEGPSGPPGPAGSPGERGAA 937

Query: 205  GEEGDQGELGEVGAQGPPGAQGLRGITGI---VGDKGEKGARGLDGEPGPQGLPGAPGDQ 261
            G  G  G  G  G QGPPGA G +G+ G    +G  G  G +G  G PGP G PG  G+ 
Sbjct: 938  GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGED 997

Query: 262  GQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPP 321
            G +G  G+ G KG +G +G  G PG PGP G  G PG  G DG PG  G +G  G  G  
Sbjct: 998  GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE 1057

Query: 322  GDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLP 381
            G  G  G PG  G+ G  G +GEKG TG     G MG  G PG +GP G  G  GPQG P
Sbjct: 1058 GTRGFNGPPGPIGLQGLPGPSGEKGETG---DVGPMGPPGPPGPRGPAGPNGADGPQGPP 1114

Query: 382  GSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEE 441
            G  G LGP G  G PG+ GS G  G PG+ GP G  G KG+ G  GEPGP G +G +G++
Sbjct: 1115 GGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDD 1174

Query: 442  GEAGERGELGDIGLPGP---------------KGSAGNPGEPGLRGPEGSRGLPGVEGPR 486
            G  G  G +G  G PGP               +G  G PG+PG  GP G  G PG  G R
Sbjct: 1175 GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1234

Query: 487  GP---PGPRGVQGEQGATGLPGVQGPPGRA----PTDQHIKQVCMRVIQEHFAEMAASLK 539
            GP   PG  G QG +GA G PG  G PG+     P     K        +    +  S+ 
Sbjct: 1235 GPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPG-----PDGLRGLPGSV- 1288

Query: 540  RPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGE 599
                G  G PG  G  GPPGP G  G PG  G  G  G KG PG +GL GP G+ GEKG+
Sbjct: 1289 ----GQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGD 1344

Query: 600  RGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCE 659
            RG PG  P G PG  G  G PG +           GP G  G PG+PGP GP G  G   
Sbjct: 1345 RGLPG--PQGSPGQKGEMGIPGAS-----------GPIGPGGPPGLPGPAGPKGAKGATG 1391

Query: 660  PASCTMQAGQRAFNKGPDP 678
            P     + G +     P P
Sbjct: 1392 PGGPKGEKGVQGPPGHPGP 1410



 Score =  500 bits (1287), Expect = e-141
 Identities = 300/680 (44%), Positives = 346/680 (50%), Gaps = 71/680 (10%)

Query: 31  QGPPGPPGPPGVPGIDGIDGDRGPKGPPG---PPGPAGEPGKPGAPGKPGT----PGADG 83
           +GPPGP GP G+ G  GI G+ GP G PG   PPG AG PG  GAPG PGT    P   G
Sbjct: 312 EGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFG 371

Query: 84  LTGPDGSPGSIGSKGQKGE---------PGVPGSRGFPGRGIPGPPGPPGTAGLPGELGR 134
             G D  P     + Q             G PG  G+ GR  PGP G PG+ GL GE G 
Sbjct: 372 SGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGR--PGPLGQPGSPGLKGESGD 429

Query: 135 VGPVGDPGRRGPPGPPGPPGPRGTIGFHD-----GDPLCPNACPPGRSGYPGLPGMRGHK 189
           +GP G  G +G  GPPG  G RG  G        GDP        G  G PGLPG +GH+
Sbjct: 430 LGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKG--DRGFDGLPGLPGEKGHR 487

Query: 190 GAKGEIGEPGRQGHKGEEGDQGELGE------------VGAQGPPGAQGLRGITGIVGDK 237
           G  G  G PG  G  GE GD GE+G             +G +GPPG  G  G+ G+ G +
Sbjct: 488 GDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQ 547

Query: 238 GEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLP 297
           G KG+ G  GEPGP G  G PG QG  GP G  GP G++G +G  G+PG+PG  G    P
Sbjct: 548 GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGP---P 604

Query: 298 GVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQM 357
           G  G++G PG  G +G  G  GP G  G +G+ GV GI G KG  GEKG  G PG  G +
Sbjct: 605 GHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDI 664

Query: 358 GNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLP 417
           G  G  G+ G PG  G  GP+   G +G  GP G PG PG +G  G  G+PGLPG PG  
Sbjct: 665 GVKGDRGEVGVPGSRGEDGPE---GPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQ 721

Query: 418 GMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSR 477
           G KG  G  G PG  GE+GA G  G++G RGE       GP G  G  G  G  G  G++
Sbjct: 722 GPKGSLGFPGFPGASGEKGARGLSGKSGPRGE------RGPTGPRGQRGPRGATGKSGAK 775

Query: 478 GLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAAS 537
           G  G +GP GPPG RG+ G QG  G PG +GPPG    D        R  +  F      
Sbjct: 776 GTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRG-EVGFQGKTGP 834

Query: 538 LKRPD-------SGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGP 590
              P        +G TG  G  G PGPPGPPGE G PG  G  G  G  GPPGA G  GP
Sbjct: 835 PGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGP 894

Query: 591 KGDLGEKGERGPPG----------RGPNGLPGAIGLPGDPGPAS----YGRNGRDGERGP 636
            G  G  GERG PG           GP+G PG  G PG+ G A      G  GR G +GP
Sbjct: 895 AGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGP 954

Query: 637 PGVAGIPGVPGPPGPPGLPG 656
           PG AG  GVPG  GP G  G
Sbjct: 955 PGAAGEKGVPGEKGPIGPTG 974



 Score =  487 bits (1254), Expect = e-137
 Identities = 291/664 (43%), Positives = 335/664 (50%), Gaps = 70/664 (10%)

Query: 24   QRGPPGEQGPPGPPGPPGVPGIDGIDGDRGP---KGPPGPPGPAGEPGKPGAPGKPGTPG 80
            QRG  G QG  GPPGPPGV G  G  G+ GP   +G PGPPGP GE G PG  GK GT G
Sbjct: 822  QRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKG 881

Query: 81   ADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGELGRVG--- 136
              G  G  G  G  G +G  GE G+PG+ G PG +G  GP GPPG AG PGE G  G   
Sbjct: 882  DPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGG 941

Query: 137  PVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNAC-----PPGRSGYPGLPGMRGHKGA 191
            P+G PGR GP GPPG  G +G  G  +  P+ P        P G  G  G PG+ G  G 
Sbjct: 942  PIGPPGRPGPQGPPGAAGEKGVPG--EKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGD 999

Query: 192  KGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGP 251
            KGE+G+PG++G KG +G+ G  G  G  GP G  G  G  G  G +G +G  G  G+ G 
Sbjct: 1000 KGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGT 1059

Query: 252  QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGT 311
            +G  G PG  G +G PG +G KG+ G  G  G PG PGP+G  G  G DG  G PG  G 
Sbjct: 1060 RGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGN 1119

Query: 312  KGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGE 371
             G PG+ G PG++G  G+ G PG+ G +G  GEKG +G PG+PG  G  G  G  GP G 
Sbjct: 1120 LGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN 1179

Query: 372  VGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGL---PGMKGDRGVVGE 428
             GP G  G PG  GE GP G  G  G  G  G PG PG PGP G    PG  G RG  G 
Sbjct: 1180 PGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS 1239

Query: 429  PGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGS---RGLPGVEGP 485
            PG +G QG  G +G+ G  G  G  G  GP G AG PG  GLRG  GS   +G PG  G 
Sbjct: 1240 PGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQ 1299

Query: 486  RGPPGP------------RGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAE 533
             GPPGP             G +GE+G  GL G+ GPPG                 E   +
Sbjct: 1300 AGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPG-----------------EQGEK 1342

Query: 534  MAASLKRPDS-----GATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLR 588
                L  P       G  G+PG  GP GP GPP            GLPG  GP GA G  
Sbjct: 1343 GDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPP------------GLPGPAGPKGAKGAT 1390

Query: 589  GPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIP--GVP 646
            GP G  GEKG +GPPG    G PG +  P         R   DG R       IP  G P
Sbjct: 1391 GPGGPKGEKGVQGPPGH--PGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAP 1448

Query: 647  GPPG 650
            G PG
Sbjct: 1449 GSPG 1452



 Score =  446 bits (1148), Expect = e-125
 Identities = 300/712 (42%), Positives = 342/712 (48%), Gaps = 129/712 (18%)

Query: 52  RGPKGPPGPPGPAGEPGKPGAPGKPGTPGAD------GLTGP--DGSPGSIGSKGQKGEP 103
           R  + P   P     P       +  TPG +       L  P  + + G  G KG+KGEP
Sbjct: 243 RAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEP 302

Query: 104 GVPGSRGFPGRGIPGPPGPPGTAGL---PGELGRVGPVGDPGRRGP------PGPPGPPG 154
            V      PG  + GPPGP G AGL   PG  G  GPVGDPG RGP      PG  G PG
Sbjct: 303 AVLE----PGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPG 358

Query: 155 PRGT-------IGFHDGDPLCPNAC------------------PPGRSGYPGLPGMRGHK 189
           P GT        G   GD     A                   PPG  GY G PG  G  
Sbjct: 359 PPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQP 418

Query: 190 GA---KGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLD 246
           G+   KGE G+ G QG +G +G  G  G+ G +G  GA G RG+ G  G KG++G  GL 
Sbjct: 419 GSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLP 478

Query: 247 GEP---------GPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLP 297
           G P         G QGLPG PG+ G+RG  GE GP+G  G  G RG+ G  GP G  G P
Sbjct: 479 GLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPP 538

Query: 298 GVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQM 357
           GV G DG  G  G+ G  G+PGPPG  G  G  G+PG  GA G  GEKG  G PG PG  
Sbjct: 539 GVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMP 598

Query: 358 GNS---GKPGQQGPP------GEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLP 408
           G+    G PG++GPP      G  GP+GP G PG RG  G  G  GL G  G  G  G P
Sbjct: 599 GSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFP 658

Query: 409 GLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEA------------GERGELGDIGLP 456
           G  G     G+KGDRG VG PG +GE G  G +G              GE+G+LG  GLP
Sbjct: 659 GFKGD---IGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLP 715

Query: 457 ------GPKGSAGNPGEPGLRGPEGSRGLPGVEGP---RGPPGPRGVQGEQGATGLPGVQ 507
                 GPKGS G PG PG  G +G+RGL G  GP   RGP GPRG +G +GATG  G +
Sbjct: 716 GYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAK 775

Query: 508 GPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFP 567
           G  G                  H       L  P  G  G PG  GPPGPPG  G  G P
Sbjct: 776 GTSGGD--------------GPHGPPGERGLPGP-QGPNGFPGPKGPPGPPGKDGLPGHP 820

Query: 568 GQMGIRGLPGIKGPPGALGLRGPK------GDLGEKGERGPPG-RGPNGLPGAI---GLP 617
           GQ G  G  G  GPPG  G+ GP+      G +GE+G  GPPG  G  GLPG     G  
Sbjct: 821 GQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTK 880

Query: 618 GDPGP-------ASYGRNGRDGERGPPGVAGIPGV------PGPPGPPGLPG 656
           GDPGP          G  G  GERG PG AG PG+       GPPGP G PG
Sbjct: 881 GDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPG 932



 Score =  444 bits (1143), Expect = e-124
 Identities = 265/612 (43%), Positives = 312/612 (50%), Gaps = 83/612 (13%)

Query: 22   AAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGE---------PGKPGA 72
            A + GP GE+G PGPPGPPG  G+ G  G  G KG PGPPG  G+         PG+ G 
Sbjct: 847  AGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGL 906

Query: 73   PGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTA---GLP 129
            PG  G PG  G  GP G PG  GS G++G  G  G  G PGR  PGP GPPG A   G+P
Sbjct: 907  PGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGR--PGPQGPPGAAGEKGVP 964

Query: 130  GELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDP----------LCPNACPPGRSGY 179
            GE G +GP G  G +GP G PGP GP G  G  DGD              N    G  G 
Sbjct: 965  GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAG-EDGDKGEVGDPGQKGTKGNKGEHGPPGP 1023

Query: 180  PGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGE 239
            PG  G  G  GA G  GEPG +G +G  G +G+ G  G  GPPG  GL+G+ G  G+KGE
Sbjct: 1024 PGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGE 1083

Query: 240  KGARGLDGEPGP------------QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGL 287
             G  G  G PGP             G  G PG  G  GPPGE G  G+ G+ G +G PG+
Sbjct: 1084 TGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGV 1143

Query: 288  PGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIP---GAKGVAGE 344
             GP+G+ G  G  G+ G PG PG KG  G  GP G+ G  G PG PG P   G +G  G 
Sbjct: 1144 KGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGA 1203

Query: 345  KGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGE------------------ 386
            KG  G  G+PGQ G+ G  G+ GPPG +G RGP G PGS G                   
Sbjct: 1204 KGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGK 1263

Query: 387  ------LGPVGSP------GLPGKLGSLGSPGL------PGLPGPPGLPGMKGDRGVVGE 428
                   GP G P      GLPG +G  G PG       PG  GPPGLPG++GD G  GE
Sbjct: 1264 TGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGE 1323

Query: 429  PGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGE---PGLRGPEGSRGLPGVEGP 485
               KG  G  G  G  GE+GE GD GLPGP+GS G  GE   PG  GP G  G PG+ GP
Sbjct: 1324 ---KGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGP 1380

Query: 486  RGPPGPRGVQGEQGATGLPGVQGPPGR-APTDQHIKQVCMRVIQEHFAEMAASLKRPDSG 544
             GP G +G  G  G  G  GVQGPPG   P  + I+ + +++ ++    +  S    +  
Sbjct: 1381 AGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDE 1440

Query: 545  ATGLPGRPGPPG 556
            A    G PG PG
Sbjct: 1441 AIPTGGAPGSPG 1452



 Score =  414 bits (1063), Expect = e-115
 Identities = 252/579 (43%), Positives = 288/579 (49%), Gaps = 76/579 (13%)

Query: 17   GLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKP 76
            GL   A   G  G +GP GPPGP G PG  G  G  GP GPPG PGP G PG  G  G P
Sbjct: 905  GLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVP 964

Query: 77   G------------TPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPP 123
            G              G  GL GP G PG  G  G KGE G PG +G  G +G  GPPGPP
Sbjct: 965  GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPP 1024

Query: 124  GTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLP 183
            G  G  G+ G  G  G+PG RGP G  G  G  GT GF+          PPG  G  GLP
Sbjct: 1025 GPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNG---------PPGPIGLQGLP 1075

Query: 184  GMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGAR 243
            G  G KG  G++G  G  G  G  G  G  G  G QGPPG  G  G  G  G+ GE G+ 
Sbjct: 1076 GPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSP 1135

Query: 244  GLDGEPGPQG------------LPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPG-- 289
            G+ GEPG +G             PG PG  G +GP G+ GPKG+ G  G  G PG PG  
Sbjct: 1136 GIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEG 1195

Query: 290  -PKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPG---AKGVAGEK 345
             P+G  G  G  G DG PG PG+ G  G+ GPPG  G +G  G PG  G    KG  G+ 
Sbjct: 1196 GPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDP 1255

Query: 346  GSTGAPGKPGQMGNSGKPGQQGP------PGEVGPRGPQGLPGSRGELGPVGSPGLPGKL 399
            G+ GAPGK G +G +G  G+ GP      PG VG +G  G  G  G  GPVG PGLPG  
Sbjct: 1256 GAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLR 1315

Query: 400  GSLGS------PGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDI 453
            G  G+      PGL GL GPPG  G KGDRG+   PGP+G  G  GE            +
Sbjct: 1316 GDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGL---PGPQGSPGQKGE------------M 1360

Query: 454  GLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPG--VQGPPG 511
            G+PG  G  G  G PGL GP G +G  G  GP GP G +GVQG  G  G PG  +Q  P 
Sbjct: 1361 GIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPI 1420

Query: 512  RAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPG 550
            + P          R++QE  A        P  GA G PG
Sbjct: 1421 QMPKKTRRSVDGSRLMQEDEA-------IPTGGAPGSPG 1452



 Score =  293 bits (751), Expect = 3e-79
 Identities = 188/417 (45%), Positives = 208/417 (49%), Gaps = 50/417 (11%)

Query: 16   LGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGK 75
            +GL       G  GE G  GP GPPG PG  G  G  G  GP GPPG  G  G PG  G+
Sbjct: 1069 IGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1128

Query: 76   PGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRV 135
            PG  G+ G+ G  G  G  G +G+KGE G PG         PGPPGP G  G  G  G  
Sbjct: 1129 PGESGSPGIQGEPGVKGPRGERGEKGESGQPGE--------PGPPGPKGPTGDDGPKGNP 1180

Query: 136  GPVGDPGRRGPPGPPGPPGPRGTIG--FHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKG 193
            GPVG PG  GPPG  GP G  G  G    DG+P  P +  PG +G  G PG  G +G  G
Sbjct: 1181 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGS--PGPTGENGPPGPLGKRGPAG 1238

Query: 194  EIGEPGRQGHKGEEGDQGELGEVGAQGP---------PGAQGLRGITGIVGDKGEKGARG 244
              G  GRQG KG +GD G +G  G  GP         PG  GLRG+ G VG +G  GA G
Sbjct: 1239 SPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATG 1298

Query: 245  LDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDG 304
              G PGP G PG PG +G  G  GE   KG  G  G  G PG  G KGD GLPG      
Sbjct: 1299 QAGPPGPVGPPGLPGLRGDAGAKGE---KGHPGLIGLIGPPGEQGEKGDRGLPGPQ---- 1351

Query: 305  IPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPG 364
              G PG KGE G PG  G  G  G PG+PG  G KG    KG+TG  G  G+ G  G PG
Sbjct: 1352 --GSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGA---KGATGPGGPKGEKGVQGPPG 1406

Query: 365  QQGPPGEVGPRGPQGLP--------GSR----GELGPV-GSPGLPGKL----GSLGS 404
              GPPGEV    P  +P        GSR     E  P  G+PG PG L    GSL S
Sbjct: 1407 HPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDS 1463


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score =  516 bits (1328), Expect = e-146
 Identities = 309/699 (44%), Positives = 359/699 (51%), Gaps = 100/699 (14%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 85
            GPPG+QG PG  G PG  G  G  G++GP+G PG PG  G  G PG PGK G PG  G  
Sbjct: 539  GPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQ 598

Query: 86   GPDGSPGSIGSKGQKGEPGVPGSRG------------FPG-RGIPGPPGPPGTAGLPGEL 132
            GP G  G +G  G +G  GV G RG            FPG +G  G  G  G  G+PG  
Sbjct: 599  GPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSR 658

Query: 133  GRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPN----ACPPGRSGYPGLPGMRGH 188
            G  GP G  GR GP G PGPPG  G  G   G P  P       P G  G+PG PG  G 
Sbjct: 659  GEDGPEGPKGRTGPTGDPGPPGLMGEKG-KLGVPGLPGYPGRQGPKGSLGFPGFPGASGE 717

Query: 189  KGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGL------------RGITGIVGD 236
            KGA+G  G+ G +G +G  G +G+ G  GA G  GA+G             RG+ G  G 
Sbjct: 718  KGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGP 777

Query: 237  KGEKGARGLDGEPGPQGLPGAPGDQGQ---------RGPPGEAGPKG---DRGAEGARGI 284
             G  G +G  G PG  GLPG PG +G+          GPPG  GP+G   + G  G RG 
Sbjct: 778  NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 837

Query: 285  PGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGL---QGLPGVPGIPGAKGV 341
            PG PGP G+ GLPG  G++G  G PG  G PGK GP G  G    +GLPG  G PG KG 
Sbjct: 838  PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 897

Query: 342  AGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGS 401
             G  G  G  G PG+ G +G  G  GPPG  GP+GP G  G +G  G  G  G  G+ G 
Sbjct: 898  EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGV 957

Query: 402  LGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGS 461
             G  GLPG  GPPG+ G  GD+G VG+PG KG +G  GE G  G  G +G +G P   G+
Sbjct: 958  QGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQP---GA 1014

Query: 462  AGNPGEPGLRGPEGSRGLPGVEGPR---GPPGPRGVQ------GEQGATGLPGVQGPPG- 511
            AG  GEPG RGP+G  G  G EG R   GPPGP G+Q      GE+G TG  G  GPPG 
Sbjct: 1015 AGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGP 1074

Query: 512  ---RAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPG 568
               R P                            +GA G  G PG  G  GPPGE G PG
Sbjct: 1075 PGPRGPAG-------------------------PNGADGPQGPPGGVGNLGPPGEKGEPG 1109

Query: 569  QM---GIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-------RGPNGLPGAIGLPG 618
            +    GI+G PG+KGP G    RG KG+ G+ GE GPPG        GP G PG +G PG
Sbjct: 1110 ESGSPGIQGEPGVKGPRGE---RGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPG 1166

Query: 619  DPG-PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
            DPG P   G  G+DG +G  G  G PG PG PGP G  G
Sbjct: 1167 DPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENG 1205



 Score =  510 bits (1314), Expect = e-144
 Identities = 308/735 (41%), Positives = 359/735 (48%), Gaps = 126/735 (17%)

Query: 23   AQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGAD 82
            A RGPPG  G  G PGP G PG  G+ G+ G  GP GP GP G  G PG  G+ G  GAD
Sbjct: 377  ALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGAD 436

Query: 83   GLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----RGIPGPPGPPGTAGLPGEL------ 132
            G  G  G PG  G +G  G PG+PG +G  G    +G+PGPPG  G  G  GE+      
Sbjct: 437  GARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLP 496

Query: 133  GRVGPVGDPGRRGPPGPPGPP---------GPRGTIGFHDGDPLCPNACPPGRSGYPGLP 183
            G  GP G  G +GPPG PGPP         GP+G++G   G+P      PPG+ G PG  
Sbjct: 497  GESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLG-PQGEP-----GPPGQQGTPGTQ 550

Query: 184  GMRGHKGAKGEIGEPGRQ---------------GHKGEEGDQGELGEVGAQGPPGAQGLR 228
            G+ G +GA G  GE G Q               GH G+EG  G  G  G  GP G  G  
Sbjct: 551  GLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYP 610

Query: 229  GITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLP 288
            G  G+ G  G +G +G  GE G  G PG  GD G +G  GE G  G RG +G  G  G  
Sbjct: 611  GPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRT 670

Query: 289  GPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVA------ 342
            GP GD G PG+ G  G  G+PG  G PG+ GP G  G  G PG  G  GA+G++      
Sbjct: 671  GPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPR 730

Query: 343  ---------GEKGSTGAPGKPGQMGNSGKPGQQGPPGE---VGPRGPQGLPGSRGELGPV 390
                     G++G  GA GK G  G SG  G  GPPGE    GP+GP G PG +G  GP 
Sbjct: 731  GERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPP 790

Query: 391  GSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGEL 450
            G  GLPG  G  G  G  G  GPPG PG+ G +G  GE GP GE+G  G  G  GE+G  
Sbjct: 791  GKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLP 850

Query: 451  GDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPP 510
            G  G  G KG  G PG PG  GP G RG PG  G  G  G  G++G +G +G PG  G P
Sbjct: 851  GTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSP 910

Query: 511  GRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQ- 569
            G                     E  A+      G  G PGRPGP GPPG  GE G PG+ 
Sbjct: 911  G---------------------ERGAA---GSGGPIGPPGRPGPQGPPGAAGEKGVPGEK 946

Query: 570  -----------MGIRGLPGIKGPPGALGLRGPKGDLGE---------KGERGPPGR---- 605
                        G  GLPG  GPPG  G  G KG++G+         KGE GPPG     
Sbjct: 947  GPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPI 1006

Query: 606  GPNGLPGAIGLPGDPG----PASYGRNGRDGER---GPPGVAGIPGVPGPP--------- 649
            GP G PGA G  G+PG       +G  G +G R   GPPG  G+ G+PGP          
Sbjct: 1007 GPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDV 1066

Query: 650  ---GPPGLPGFCEPA 661
               GPPG PG   PA
Sbjct: 1067 GPMGPPGPPGPRGPA 1081



 Score =  505 bits (1300), Expect = e-143
 Identities = 299/679 (44%), Positives = 344/679 (50%), Gaps = 68/679 (10%)

Query: 25   RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGL 84
            +G  G  GP GPPG  G+PG  G +G  GPKGPPGPPG   + G PG PG+ G  G  G 
Sbjct: 754  KGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPG---KDGLPGHPGQRGEVGFQGK 810

Query: 85   TGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRR 144
            TGP G PG +G +G  GE G  G RG PG     PPGPPG  GLPG  G+ G  GDPG  
Sbjct: 811  TGPPGPPGVVGPQGAAGETGPMGERGHPG-----PPGPPGEQGLPGTAGKEGTKGDPG-- 863

Query: 145  GPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHK 204
             PPG PG  GP G  GF     L      PG +G PGL G  G  G  G  G PG +G  
Sbjct: 864  -PPGAPGKDGPAGLRGFPGERGL------PGTAGGPGLKGNEGPSGPPGPAGSPGERGAA 916

Query: 205  GEEGDQGELGEVGAQGPPGAQGLRGITGI---VGDKGEKGARGLDGEPGPQGLPGAPGDQ 261
            G  G  G  G  G QGPPGA G +G+ G    +G  G  G +G  G PGP G PG  G+ 
Sbjct: 917  GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGED 976

Query: 262  GQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPP 321
            G +G  G+ G KG +G +G  G PG PGP G  G PG  G DG PG  G +G  G  G  
Sbjct: 977  GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE 1036

Query: 322  GDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLP 381
            G  G  G PG  G+ G  G +GEKG TG     G MG  G PG +GP G  G  GPQG P
Sbjct: 1037 GTRGFNGPPGPIGLQGLPGPSGEKGETG---DVGPMGPPGPPGPRGPAGPNGADGPQGPP 1093

Query: 382  GSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEE 441
            G  G LGP G  G PG+ GS G  G PG+ GP G  G KG+ G  GEPGP G +G +G++
Sbjct: 1094 GGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDD 1153

Query: 442  GEAGERGELGDIGLPGP---------------KGSAGNPGEPGLRGPEGSRGLPGVEGPR 486
            G  G  G +G  G PGP               +G  G PG+PG  GP G  G PG  G R
Sbjct: 1154 GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1213

Query: 487  GP---PGPRGVQGEQGATGLPGVQGPPGRA----PTDQHIKQVCMRVIQEHFAEMAASLK 539
            GP   PG  G QG +GA G PG  G PG+     P     K        +    +  S+ 
Sbjct: 1214 GPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPG-----PDGLRGLPGSV- 1267

Query: 540  RPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGE 599
                G  G PG  G  GPPGP G  G PG  G  G  G KG PG +GL GP G+ GEKG+
Sbjct: 1268 ----GQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGD 1323

Query: 600  RGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCE 659
            RG PG  P G PG  G  G PG +           GP G  G PG+PGP GP G  G   
Sbjct: 1324 RGLPG--PQGSPGQKGEMGIPGAS-----------GPIGPGGPPGLPGPAGPKGAKGATG 1370

Query: 660  PASCTMQAGQRAFNKGPDP 678
            P     + G +     P P
Sbjct: 1371 PGGPKGEKGVQGPPGHPGP 1389



 Score =  500 bits (1287), Expect = e-141
 Identities = 300/680 (44%), Positives = 346/680 (50%), Gaps = 71/680 (10%)

Query: 31  QGPPGPPGPPGVPGIDGIDGDRGPKGPPG---PPGPAGEPGKPGAPGKPGT----PGADG 83
           +GPPGP GP G+ G  GI G+ GP G PG   PPG AG PG  GAPG PGT    P   G
Sbjct: 291 EGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFG 350

Query: 84  LTGPDGSPGSIGSKGQKGE---------PGVPGSRGFPGRGIPGPPGPPGTAGLPGELGR 134
             G D  P     + Q             G PG  G+ GR  PGP G PG+ GL GE G 
Sbjct: 351 SGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGR--PGPLGQPGSPGLKGESGD 408

Query: 135 VGPVGDPGRRGPPGPPGPPGPRGTIGFHD-----GDPLCPNACPPGRSGYPGLPGMRGHK 189
           +GP G  G +G  GPPG  G RG  G        GDP        G  G PGLPG +GH+
Sbjct: 409 LGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKG--DRGFDGLPGLPGEKGHR 466

Query: 190 GAKGEIGEPGRQGHKGEEGDQGELGE------------VGAQGPPGAQGLRGITGIVGDK 237
           G  G  G PG  G  GE GD GE+G             +G +GPPG  G  G+ G+ G +
Sbjct: 467 GDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQ 526

Query: 238 GEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLP 297
           G KG+ G  GEPGP G  G PG QG  GP G  GP G++G +G  G+PG+PG  G    P
Sbjct: 527 GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGP---P 583

Query: 298 GVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQM 357
           G  G++G PG  G +G  G  GP G  G +G+ GV GI G KG  GEKG  G PG  G +
Sbjct: 584 GHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDI 643

Query: 358 GNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLP 417
           G  G  G+ G PG  G  GP+   G +G  GP G PG PG +G  G  G+PGLPG PG  
Sbjct: 644 GVKGDRGEVGVPGSRGEDGPE---GPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQ 700

Query: 418 GMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSR 477
           G KG  G  G PG  GE+GA G  G++G RGE       GP G  G  G  G  G  G++
Sbjct: 701 GPKGSLGFPGFPGASGEKGARGLSGKSGPRGE------RGPTGPRGQRGPRGATGKSGAK 754

Query: 478 GLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAAS 537
           G  G +GP GPPG RG+ G QG  G PG +GPPG    D        R  +  F      
Sbjct: 755 GTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRG-EVGFQGKTGP 813

Query: 538 LKRPD-------SGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGP 590
              P        +G TG  G  G PGPPGPPGE G PG  G  G  G  GPPGA G  GP
Sbjct: 814 PGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGP 873

Query: 591 KGDLGEKGERGPPG----------RGPNGLPGAIGLPGDPGPAS----YGRNGRDGERGP 636
            G  G  GERG PG           GP+G PG  G PG+ G A      G  GR G +GP
Sbjct: 874 AGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGP 933

Query: 637 PGVAGIPGVPGPPGPPGLPG 656
           PG AG  GVPG  GP G  G
Sbjct: 934 PGAAGEKGVPGEKGPIGPTG 953



 Score =  487 bits (1254), Expect = e-137
 Identities = 291/664 (43%), Positives = 335/664 (50%), Gaps = 70/664 (10%)

Query: 24   QRGPPGEQGPPGPPGPPGVPGIDGIDGDRGP---KGPPGPPGPAGEPGKPGAPGKPGTPG 80
            QRG  G QG  GPPGPPGV G  G  G+ GP   +G PGPPGP GE G PG  GK GT G
Sbjct: 801  QRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKG 860

Query: 81   ADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGELGRVG--- 136
              G  G  G  G  G +G  GE G+PG+ G PG +G  GP GPPG AG PGE G  G   
Sbjct: 861  DPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGG 920

Query: 137  PVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNAC-----PPGRSGYPGLPGMRGHKGA 191
            P+G PGR GP GPPG  G +G  G  +  P+ P        P G  G  G PG+ G  G 
Sbjct: 921  PIGPPGRPGPQGPPGAAGEKGVPG--EKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGD 978

Query: 192  KGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGP 251
            KGE+G+PG++G KG +G+ G  G  G  GP G  G  G  G  G +G +G  G  G+ G 
Sbjct: 979  KGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGT 1038

Query: 252  QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGT 311
            +G  G PG  G +G PG +G KG+ G  G  G PG PGP+G  G  G DG  G PG  G 
Sbjct: 1039 RGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGN 1098

Query: 312  KGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGE 371
             G PG+ G PG++G  G+ G PG+ G +G  GEKG +G PG+PG  G  G  G  GP G 
Sbjct: 1099 LGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN 1158

Query: 372  VGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGL---PGMKGDRGVVGE 428
             GP G  G PG  GE GP G  G  G  G  G PG PG PGP G    PG  G RG  G 
Sbjct: 1159 PGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS 1218

Query: 429  PGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGS---RGLPGVEGP 485
            PG +G QG  G +G+ G  G  G  G  GP G AG PG  GLRG  GS   +G PG  G 
Sbjct: 1219 PGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQ 1278

Query: 486  RGPPGP------------RGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAE 533
             GPPGP             G +GE+G  GL G+ GPPG                 E   +
Sbjct: 1279 AGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPG-----------------EQGEK 1321

Query: 534  MAASLKRPDS-----GATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLR 588
                L  P       G  G+PG  GP GP GPP            GLPG  GP GA G  
Sbjct: 1322 GDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPP------------GLPGPAGPKGAKGAT 1369

Query: 589  GPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIP--GVP 646
            GP G  GEKG +GPPG    G PG +  P         R   DG R       IP  G P
Sbjct: 1370 GPGGPKGEKGVQGPPGH--PGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAP 1427

Query: 647  GPPG 650
            G PG
Sbjct: 1428 GSPG 1431



 Score =  444 bits (1143), Expect = e-124
 Identities = 265/612 (43%), Positives = 312/612 (50%), Gaps = 83/612 (13%)

Query: 22   AAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGE---------PGKPGA 72
            A + GP GE+G PGPPGPPG  G+ G  G  G KG PGPPG  G+         PG+ G 
Sbjct: 826  AGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGL 885

Query: 73   PGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTA---GLP 129
            PG  G PG  G  GP G PG  GS G++G  G  G  G PGR  PGP GPPG A   G+P
Sbjct: 886  PGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGR--PGPQGPPGAAGEKGVP 943

Query: 130  GELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDP----------LCPNACPPGRSGY 179
            GE G +GP G  G +GP G PGP GP G  G  DGD              N    G  G 
Sbjct: 944  GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAG-EDGDKGEVGDPGQKGTKGNKGEHGPPGP 1002

Query: 180  PGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGE 239
            PG  G  G  GA G  GEPG +G +G  G +G+ G  G  GPPG  GL+G+ G  G+KGE
Sbjct: 1003 PGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGE 1062

Query: 240  KGARGLDGEPGP------------QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGL 287
             G  G  G PGP             G  G PG  G  GPPGE G  G+ G+ G +G PG+
Sbjct: 1063 TGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGV 1122

Query: 288  PGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIP---GAKGVAGE 344
             GP+G+ G  G  G+ G PG PG KG  G  GP G+ G  G PG PG P   G +G  G 
Sbjct: 1123 KGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGA 1182

Query: 345  KGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGE------------------ 386
            KG  G  G+PGQ G+ G  G+ GPPG +G RGP G PGS G                   
Sbjct: 1183 KGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGK 1242

Query: 387  ------LGPVGSP------GLPGKLGSLGSPGL------PGLPGPPGLPGMKGDRGVVGE 428
                   GP G P      GLPG +G  G PG       PG  GPPGLPG++GD G  GE
Sbjct: 1243 TGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGE 1302

Query: 429  PGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGE---PGLRGPEGSRGLPGVEGP 485
               KG  G  G  G  GE+GE GD GLPGP+GS G  GE   PG  GP G  G PG+ GP
Sbjct: 1303 ---KGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGP 1359

Query: 486  RGPPGPRGVQGEQGATGLPGVQGPPGR-APTDQHIKQVCMRVIQEHFAEMAASLKRPDSG 544
             GP G +G  G  G  G  GVQGPPG   P  + I+ + +++ ++    +  S    +  
Sbjct: 1360 AGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDE 1419

Query: 545  ATGLPGRPGPPG 556
            A    G PG PG
Sbjct: 1420 AIPTGGAPGSPG 1431



 Score =  416 bits (1070), Expect = e-116
 Identities = 258/618 (41%), Positives = 299/618 (48%), Gaps = 75/618 (12%)

Query: 92  GSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGL---PGELGRVGPVGDPGRRGPPG 148
           G  G KG+KGEP V      PG  + GPPGP G AGL   PG  G  GPVGDPG RGPPG
Sbjct: 270 GPRGLKGEKGEPAVLE----PGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPG 325

Query: 149 PPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEG 208
             G PG  G  G      + P     G  G    P +   +     I +  R   +G  G
Sbjct: 326 RAGLPGSDGAPGPPGTSLMLPFRF--GSGGGDKGPVVAAQEAQAQAILQQARLALRGPPG 383

Query: 209 DQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPG 268
             G  G  G  G PG+ GL+G +G +G +G +G +GL G PG  G  G  G  G RG PG
Sbjct: 384 PMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPG 443

Query: 269 EAGPKGDRGAEGARGIPGLPGPKGDTG---LPGVDGRDGIPGMPGTKGEPGKPGPPGDAG 325
           + G KGDRG +G  G+PG  G +GDTG   LPG  G DG  G  G  G  G PG  G  G
Sbjct: 444 DPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRG 503

Query: 326 LQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRG 385
           L G  G PGIPG  GV G  G  G  G  G  G  G PGQQG PG  G  GPQG  G  G
Sbjct: 504 LLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHG 563

Query: 386 ELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGD---RGVVGEPGPKGEQGASGEEG 442
           E GP G PGLPG  GS G PG PG  GPPG  G +G    +G +G PGP+G +G  G  G
Sbjct: 564 EKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRG 623

Query: 443 EAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATG 502
             G +GE G+ G PG KG  G      ++G  G  G+PG  G  GP GP+G  G  G  G
Sbjct: 624 LKGHKGEKGEDGFPGFKGDIG------VKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPG 677

Query: 503 LPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPG 562
            PG+ G  G+                               G  GLPG PG  GP G  G
Sbjct: 678 PPGLMGEKGKL------------------------------GVPGLPGYPGRQGPKGSLG 707

Query: 563 ENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR----------GPNGLPG 612
             GFPG  G +G  G+ G  G  G RGP G  G++G RG  G+          GP+G PG
Sbjct: 708 FPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPG 767

Query: 613 AIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPG------------PPGPPGLPGFCEP 660
             GLPG  GP  +   G  G  GPPG  G+PG PG            PPGPPG+ G    
Sbjct: 768 ERGLPGPQGPNGFP--GPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGA 825

Query: 661 ASCTMQAGQRAFNKGPDP 678
           A  T   G+R     P P
Sbjct: 826 AGETGPMGERGHPGPPGP 843



 Score =  414 bits (1063), Expect = e-115
 Identities = 252/579 (43%), Positives = 288/579 (49%), Gaps = 76/579 (13%)

Query: 17   GLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKP 76
            GL   A   G  G +GP GPPGP G PG  G  G  GP GPPG PGP G PG  G  G P
Sbjct: 884  GLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVP 943

Query: 77   G------------TPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPP 123
            G              G  GL GP G PG  G  G KGE G PG +G  G +G  GPPGPP
Sbjct: 944  GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPP 1003

Query: 124  GTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLP 183
            G  G  G+ G  G  G+PG RGP G  G  G  GT GF+          PPG  G  GLP
Sbjct: 1004 GPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNG---------PPGPIGLQGLP 1054

Query: 184  GMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGAR 243
            G  G KG  G++G  G  G  G  G  G  G  G QGPPG  G  G  G  G+ GE G+ 
Sbjct: 1055 GPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSP 1114

Query: 244  GLDGEPGPQG------------LPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPG-- 289
            G+ GEPG +G             PG PG  G +GP G+ GPKG+ G  G  G PG PG  
Sbjct: 1115 GIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEG 1174

Query: 290  -PKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPG---AKGVAGEK 345
             P+G  G  G  G DG PG PG+ G  G+ GPPG  G +G  G PG  G    KG  G+ 
Sbjct: 1175 GPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDP 1234

Query: 346  GSTGAPGKPGQMGNSGKPGQQGP------PGEVGPRGPQGLPGSRGELGPVGSPGLPGKL 399
            G+ GAPGK G +G +G  G+ GP      PG VG +G  G  G  G  GPVG PGLPG  
Sbjct: 1235 GAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLR 1294

Query: 400  GSLGS------PGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDI 453
            G  G+      PGL GL GPPG  G KGDRG+   PGP+G  G  GE            +
Sbjct: 1295 GDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGL---PGPQGSPGQKGE------------M 1339

Query: 454  GLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPG--VQGPPG 511
            G+PG  G  G  G PGL GP G +G  G  GP GP G +GVQG  G  G PG  +Q  P 
Sbjct: 1340 GIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPI 1399

Query: 512  RAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPG 550
            + P          R++QE  A        P  GA G PG
Sbjct: 1400 QMPKKTRRSVDGSRLMQEDEA-------IPTGGAPGSPG 1431



 Score =  357 bits (916), Expect = 2e-98
 Identities = 239/621 (38%), Positives = 274/621 (44%), Gaps = 130/621 (20%)

Query: 180 PGLPGMRGHKGAKGEIGEP-------------------GRQGHKGEEGDQGELGEVGAQG 220
           P      G +G KGE GEP                   G  G  G +G+ G +G+ G +G
Sbjct: 263 PQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERG 322

Query: 221 PPGAQGLRGITGIVGD----------------------------------------KGEK 240
           PPG  GL G  G  G                                         +G  
Sbjct: 323 PPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPP 382

Query: 241 GARGLDGEPGPQGLPGAP---------------GDQGQRGPPGEAGPKGDRGAEGARGIP 285
           G  G  G PGP G PG+P               G QG  GPPG+AG +G  GA+GARG+P
Sbjct: 383 GPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMP 442

Query: 286 GLPGPKGD---TGLPGVDGR---------DGIPGMPGTKGEPGK---------PGPPGDA 324
           G PG KGD    GLPG+ G           G+PG PG  GE G          PG  G  
Sbjct: 443 GDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPR 502

Query: 325 GLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSR 384
           GL G  G PGIPG  GV G  G  G  G  G  G  G PGQQG PG  G  GPQG  G  
Sbjct: 503 GLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPH 562

Query: 385 GELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMK---GDRGVVGEPGPKGEQGASGEE 441
           GE GP G PGLPG  GS G PG PG  GPPG  G +   G +G +G PGP+G +G  G  
Sbjct: 563 GEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIR 622

Query: 442 GEAGERGELGDIGLP------GPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQ 495
           G  G +GE G+ G P      G KG  G  G PG RG +G  G  G  GP G PGP G+ 
Sbjct: 623 GLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLM 682

Query: 496 GEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLK---RPDSGATGLPGRP 552
           GE+G  G+PG+ G PGR      +                 S K   R + G TG  G+ 
Sbjct: 683 GEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQR 742

Query: 553 GP---------------PGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEK 597
           GP                GP GPPGE G PG  G  G PG KGPPG  G  G  G  G++
Sbjct: 743 GPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQR 802

Query: 598 GERGPPGR-GPNGLPGAIGLPGDPGPAS-YGRNGRDGERGPPGVAGIP------GVPGPP 649
           GE G  G+ GP G PG +G  G  G     G  G  G  GPPG  G+P      G  G P
Sbjct: 803 GEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDP 862

Query: 650 GPPGLPGFCEPASCTMQAGQR 670
           GPPG PG   PA      G+R
Sbjct: 863 GPPGAPGKDGPAGLRGFPGER 883



 Score =  293 bits (751), Expect = 3e-79
 Identities = 188/417 (45%), Positives = 208/417 (49%), Gaps = 50/417 (11%)

Query: 16   LGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGK 75
            +GL       G  GE G  GP GPPG PG  G  G  G  GP GPPG  G  G PG  G+
Sbjct: 1048 IGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1107

Query: 76   PGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRV 135
            PG  G+ G+ G  G  G  G +G+KGE G PG         PGPPGP G  G  G  G  
Sbjct: 1108 PGESGSPGIQGEPGVKGPRGERGEKGESGQPGE--------PGPPGPKGPTGDDGPKGNP 1159

Query: 136  GPVGDPGRRGPPGPPGPPGPRGTIG--FHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKG 193
            GPVG PG  GPPG  GP G  G  G    DG+P  P +  PG +G  G PG  G +G  G
Sbjct: 1160 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGS--PGPTGENGPPGPLGKRGPAG 1217

Query: 194  EIGEPGRQGHKGEEGDQGELGEVGAQGP---------PGAQGLRGITGIVGDKGEKGARG 244
              G  GRQG KG +GD G +G  G  GP         PG  GLRG+ G VG +G  GA G
Sbjct: 1218 SPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATG 1277

Query: 245  LDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDG 304
              G PGP G PG PG +G  G  GE   KG  G  G  G PG  G KGD GLPG      
Sbjct: 1278 QAGPPGPVGPPGLPGLRGDAGAKGE---KGHPGLIGLIGPPGEQGEKGDRGLPGPQ---- 1330

Query: 305  IPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPG 364
              G PG KGE G PG  G  G  G PG+PG  G KG    KG+TG  G  G+ G  G PG
Sbjct: 1331 --GSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGA---KGATGPGGPKGEKGVQGPPG 1385

Query: 365  QQGPPGEVGPRGPQGLP--------GSR----GELGPV-GSPGLPGKL----GSLGS 404
              GPPGEV    P  +P        GSR     E  P  G+PG PG L    GSL S
Sbjct: 1386 HPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDS 1442



 Score =  197 bits (501), Expect = 3e-50
 Identities = 137/369 (37%), Positives = 162/369 (43%), Gaps = 112/369 (30%)

Query: 362 KPGQQGPPGEVGPRGPQGLPGSRGE-------------------------------LGPV 390
           +P  Q P  +    GP+GL G +GE                                GPV
Sbjct: 257 RPQNQEPQSQAA-HGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPV 315

Query: 391 GSPGLPGKLGSLGSPGLPGLPGPPGLPGM--------KGDRGVV---------------- 426
           G PG  G  G  G PG  G PGPPG   M         GD+G V                
Sbjct: 316 GDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQAR 375

Query: 427 ----GEPGP---KGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGL 479
               G PGP    G  G  G+ G  G +GE GD+G  GP+G  G  G P   G  G RG 
Sbjct: 376 LALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPP---GKAGRRGR 432

Query: 480 PGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLK 539
            G +G RG PG  GV+G++G  GLPG+ G  G                            
Sbjct: 433 AGADGARGMPGDPGVKGDRGFDGLPGLPGEKGH--------------------------- 465

Query: 540 RPDSGATGLPGRPGPP---------GPPGPPGENGFPGQMGIRGLPGIKGPPGALGL--- 587
           R D+GA GLPG PG           GP G PGE+G  G +G +G PGI GPPG  G+   
Sbjct: 466 RGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGP 525

Query: 588 RGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPG 647
           +GPKG LG +GE GPPG+   G PG  GLPG  G       G  GE+GP G  G+PG+PG
Sbjct: 526 QGPKGSLGPQGEPGPPGQ--QGTPGTQGLPGPQGAI-----GPHGEKGPQGKPGLPGMPG 578

Query: 648 PPGPPGLPG 656
             GPPG PG
Sbjct: 579 SDGPPGHPG 587


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score =  516 bits (1328), Expect = e-146
 Identities = 309/699 (44%), Positives = 359/699 (51%), Gaps = 100/699 (14%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 85
            GPPG+QG PG  G PG  G  G  G++GP+G PG PG  G  G PG PGK G PG  G  
Sbjct: 646  GPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQ 705

Query: 86   GPDGSPGSIGSKGQKGEPGVPGSRG------------FPG-RGIPGPPGPPGTAGLPGEL 132
            GP G  G +G  G +G  GV G RG            FPG +G  G  G  G  G+PG  
Sbjct: 706  GPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSR 765

Query: 133  GRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPN----ACPPGRSGYPGLPGMRGH 188
            G  GP G  GR GP G PGPPG  G  G   G P  P       P G  G+PG PG  G 
Sbjct: 766  GEDGPEGPKGRTGPTGDPGPPGLMGEKG-KLGVPGLPGYPGRQGPKGSLGFPGFPGASGE 824

Query: 189  KGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGL------------RGITGIVGD 236
            KGA+G  G+ G +G +G  G +G+ G  GA G  GA+G             RG+ G  G 
Sbjct: 825  KGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGP 884

Query: 237  KGEKGARGLDGEPGPQGLPGAPGDQGQ---------RGPPGEAGPKG---DRGAEGARGI 284
             G  G +G  G PG  GLPG PG +G+          GPPG  GP+G   + G  G RG 
Sbjct: 885  NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 944

Query: 285  PGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGL---QGLPGVPGIPGAKGV 341
            PG PGP G+ GLPG  G++G  G PG  G PGK GP G  G    +GLPG  G PG KG 
Sbjct: 945  PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 1004

Query: 342  AGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGS 401
             G  G  G  G PG+ G +G  G  GPPG  GP+GP G  G +G  G  G  G  G+ G 
Sbjct: 1005 EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGV 1064

Query: 402  LGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGS 461
             G  GLPG  GPPG+ G  GD+G VG+PG KG +G  GE G  G  G +G +G P   G+
Sbjct: 1065 QGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQP---GA 1121

Query: 462  AGNPGEPGLRGPEGSRGLPGVEGPR---GPPGPRGVQ------GEQGATGLPGVQGPPG- 511
            AG  GEPG RGP+G  G  G EG R   GPPGP G+Q      GE+G TG  G  GPPG 
Sbjct: 1122 AGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGP 1181

Query: 512  ---RAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPG 568
               R P                            +GA G  G PG  G  GPPGE G PG
Sbjct: 1182 PGPRGPAG-------------------------PNGADGPQGPPGGVGNLGPPGEKGEPG 1216

Query: 569  QM---GIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPG-------RGPNGLPGAIGLPG 618
            +    GI+G PG+KGP G    RG KG+ G+ GE GPPG        GP G PG +G PG
Sbjct: 1217 ESGSPGIQGEPGVKGPRGE---RGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPG 1273

Query: 619  DPG-PASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
            DPG P   G  G+DG +G  G  G PG PG PGP G  G
Sbjct: 1274 DPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENG 1312



 Score =  510 bits (1314), Expect = e-144
 Identities = 308/735 (41%), Positives = 359/735 (48%), Gaps = 126/735 (17%)

Query: 23   AQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGAD 82
            A RGPPG  G  G PGP G PG  G+ G+ G  GP GP GP G  G PG  G+ G  GAD
Sbjct: 484  ALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGAD 543

Query: 83   GLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----RGIPGPPGPPGTAGLPGEL------ 132
            G  G  G PG  G +G  G PG+PG +G  G    +G+PGPPG  G  G  GE+      
Sbjct: 544  GARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLP 603

Query: 133  GRVGPVGDPGRRGPPGPPGPP---------GPRGTIGFHDGDPLCPNACPPGRSGYPGLP 183
            G  GP G  G +GPPG PGPP         GP+G++G   G+P      PPG+ G PG  
Sbjct: 604  GESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLG-PQGEP-----GPPGQQGTPGTQ 657

Query: 184  GMRGHKGAKGEIGEPGRQ---------------GHKGEEGDQGELGEVGAQGPPGAQGLR 228
            G+ G +GA G  GE G Q               GH G+EG  G  G  G  GP G  G  
Sbjct: 658  GLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYP 717

Query: 229  GITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLP 288
            G  G+ G  G +G +G  GE G  G PG  GD G +G  GE G  G RG +G  G  G  
Sbjct: 718  GPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRT 777

Query: 289  GPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVA------ 342
            GP GD G PG+ G  G  G+PG  G PG+ GP G  G  G PG  G  GA+G++      
Sbjct: 778  GPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPR 837

Query: 343  ---------GEKGSTGAPGKPGQMGNSGKPGQQGPPGE---VGPRGPQGLPGSRGELGPV 390
                     G++G  GA GK G  G SG  G  GPPGE    GP+GP G PG +G  GP 
Sbjct: 838  GERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPP 897

Query: 391  GSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGEL 450
            G  GLPG  G  G  G  G  GPPG PG+ G +G  GE GP GE+G  G  G  GE+G  
Sbjct: 898  GKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLP 957

Query: 451  GDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPP 510
            G  G  G KG  G PG PG  GP G RG PG  G  G  G  G++G +G +G PG  G P
Sbjct: 958  GTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSP 1017

Query: 511  GRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQ- 569
            G                     E  A+      G  G PGRPGP GPPG  GE G PG+ 
Sbjct: 1018 G---------------------ERGAA---GSGGPIGPPGRPGPQGPPGAAGEKGVPGEK 1053

Query: 570  -----------MGIRGLPGIKGPPGALGLRGPKGDLGE---------KGERGPPGR---- 605
                        G  GLPG  GPPG  G  G KG++G+         KGE GPPG     
Sbjct: 1054 GPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPI 1113

Query: 606  GPNGLPGAIGLPGDPG----PASYGRNGRDGER---GPPGVAGIPGVPGPP--------- 649
            GP G PGA G  G+PG       +G  G +G R   GPPG  G+ G+PGP          
Sbjct: 1114 GPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDV 1173

Query: 650  ---GPPGLPGFCEPA 661
               GPPG PG   PA
Sbjct: 1174 GPMGPPGPPGPRGPA 1188



 Score =  505 bits (1300), Expect = e-143
 Identities = 299/679 (44%), Positives = 344/679 (50%), Gaps = 68/679 (10%)

Query: 25   RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGL 84
            +G  G  GP GPPG  G+PG  G +G  GPKGPPGPPG   + G PG PG+ G  G  G 
Sbjct: 861  KGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPG---KDGLPGHPGQRGEVGFQGK 917

Query: 85   TGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRR 144
            TGP G PG +G +G  GE G  G RG PG     PPGPPG  GLPG  G+ G  GDPG  
Sbjct: 918  TGPPGPPGVVGPQGAAGETGPMGERGHPG-----PPGPPGEQGLPGTAGKEGTKGDPG-- 970

Query: 145  GPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHK 204
             PPG PG  GP G  GF     L      PG +G PGL G  G  G  G  G PG +G  
Sbjct: 971  -PPGAPGKDGPAGLRGFPGERGL------PGTAGGPGLKGNEGPSGPPGPAGSPGERGAA 1023

Query: 205  GEEGDQGELGEVGAQGPPGAQGLRGITGI---VGDKGEKGARGLDGEPGPQGLPGAPGDQ 261
            G  G  G  G  G QGPPGA G +G+ G    +G  G  G +G  G PGP G PG  G+ 
Sbjct: 1024 GSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGED 1083

Query: 262  GQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPP 321
            G +G  G+ G KG +G +G  G PG PGP G  G PG  G DG PG  G +G  G  G  
Sbjct: 1084 GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDE 1143

Query: 322  GDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLP 381
            G  G  G PG  G+ G  G +GEKG TG     G MG  G PG +GP G  G  GPQG P
Sbjct: 1144 GTRGFNGPPGPIGLQGLPGPSGEKGETG---DVGPMGPPGPPGPRGPAGPNGADGPQGPP 1200

Query: 382  GSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEE 441
            G  G LGP G  G PG+ GS G  G PG+ GP G  G KG+ G  GEPGP G +G +G++
Sbjct: 1201 GGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDD 1260

Query: 442  GEAGERGELGDIGLPGP---------------KGSAGNPGEPGLRGPEGSRGLPGVEGPR 486
            G  G  G +G  G PGP               +G  G PG+PG  GP G  G PG  G R
Sbjct: 1261 GPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1320

Query: 487  GP---PGPRGVQGEQGATGLPGVQGPPGRA----PTDQHIKQVCMRVIQEHFAEMAASLK 539
            GP   PG  G QG +GA G PG  G PG+     P     K        +    +  S+ 
Sbjct: 1321 GPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPG-----PDGLRGLPGSV- 1374

Query: 540  RPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGE 599
                G  G PG  G  GPPGP G  G PG  G  G  G KG PG +GL GP G+ GEKG+
Sbjct: 1375 ----GQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGD 1430

Query: 600  RGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCE 659
            RG PG  P G PG  G  G PG +           GP G  G PG+PGP GP G  G   
Sbjct: 1431 RGLPG--PQGSPGQKGEMGIPGAS-----------GPIGPGGPPGLPGPAGPKGAKGATG 1477

Query: 660  PASCTMQAGQRAFNKGPDP 678
            P     + G +     P P
Sbjct: 1478 PGGPKGEKGVQGPPGHPGP 1496



 Score =  500 bits (1287), Expect = e-141
 Identities = 300/680 (44%), Positives = 346/680 (50%), Gaps = 71/680 (10%)

Query: 31   QGPPGPPGPPGVPGIDGIDGDRGPKGPPG---PPGPAGEPGKPGAPGKPGT----PGADG 83
            +GPPGP GP G+ G  GI G+ GP G PG   PPG AG PG  GAPG PGT    P   G
Sbjct: 398  EGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFG 457

Query: 84   LTGPDGSPGSIGSKGQKGE---------PGVPGSRGFPGRGIPGPPGPPGTAGLPGELGR 134
              G D  P     + Q             G PG  G+ GR  PGP G PG+ GL GE G 
Sbjct: 458  SGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGR--PGPLGQPGSPGLKGESGD 515

Query: 135  VGPVGDPGRRGPPGPPGPPGPRGTIGFHD-----GDPLCPNACPPGRSGYPGLPGMRGHK 189
            +GP G  G +G  GPPG  G RG  G        GDP        G  G PGLPG +GH+
Sbjct: 516  LGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKG--DRGFDGLPGLPGEKGHR 573

Query: 190  GAKGEIGEPGRQGHKGEEGDQGELGE------------VGAQGPPGAQGLRGITGIVGDK 237
            G  G  G PG  G  GE GD GE+G             +G +GPPG  G  G+ G+ G +
Sbjct: 574  GDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQ 633

Query: 238  GEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLP 297
            G KG+ G  GEPGP G  G PG QG  GP G  GP G++G +G  G+PG+PG  G    P
Sbjct: 634  GPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGP---P 690

Query: 298  GVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQM 357
            G  G++G PG  G +G  G  GP G  G +G+ GV GI G KG  GEKG  G PG  G +
Sbjct: 691  GHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDI 750

Query: 358  GNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLP 417
            G  G  G+ G PG  G  GP+   G +G  GP G PG PG +G  G  G+PGLPG PG  
Sbjct: 751  GVKGDRGEVGVPGSRGEDGPE---GPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQ 807

Query: 418  GMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSR 477
            G KG  G  G PG  GE+GA G  G++G RGE       GP G  G  G  G  G  G++
Sbjct: 808  GPKGSLGFPGFPGASGEKGARGLSGKSGPRGE------RGPTGPRGQRGPRGATGKSGAK 861

Query: 478  GLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAAS 537
            G  G +GP GPPG RG+ G QG  G PG +GPPG    D        R  +  F      
Sbjct: 862  GTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRG-EVGFQGKTGP 920

Query: 538  LKRPD-------SGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGP 590
               P        +G TG  G  G PGPPGPPGE G PG  G  G  G  GPPGA G  GP
Sbjct: 921  PGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGP 980

Query: 591  KGDLGEKGERGPPG----------RGPNGLPGAIGLPGDPGPAS----YGRNGRDGERGP 636
             G  G  GERG PG           GP+G PG  G PG+ G A      G  GR G +GP
Sbjct: 981  AGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGP 1040

Query: 637  PGVAGIPGVPGPPGPPGLPG 656
            PG AG  GVPG  GP G  G
Sbjct: 1041 PGAAGEKGVPGEKGPIGPTG 1060



 Score =  487 bits (1254), Expect = e-137
 Identities = 291/664 (43%), Positives = 335/664 (50%), Gaps = 70/664 (10%)

Query: 24   QRGPPGEQGPPGPPGPPGVPGIDGIDGDRGP---KGPPGPPGPAGEPGKPGAPGKPGTPG 80
            QRG  G QG  GPPGPPGV G  G  G+ GP   +G PGPPGP GE G PG  GK GT G
Sbjct: 908  QRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKG 967

Query: 81   ADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGELGRVG--- 136
              G  G  G  G  G +G  GE G+PG+ G PG +G  GP GPPG AG PGE G  G   
Sbjct: 968  DPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGG 1027

Query: 137  PVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNAC-----PPGRSGYPGLPGMRGHKGA 191
            P+G PGR GP GPPG  G +G  G  +  P+ P        P G  G  G PG+ G  G 
Sbjct: 1028 PIGPPGRPGPQGPPGAAGEKGVPG--EKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGD 1085

Query: 192  KGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGP 251
            KGE+G+PG++G KG +G+ G  G  G  GP G  G  G  G  G +G +G  G  G+ G 
Sbjct: 1086 KGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGT 1145

Query: 252  QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGT 311
            +G  G PG  G +G PG +G KG+ G  G  G PG PGP+G  G  G DG  G PG  G 
Sbjct: 1146 RGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGN 1205

Query: 312  KGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGE 371
             G PG+ G PG++G  G+ G PG+ G +G  GEKG +G PG+PG  G  G  G  GP G 
Sbjct: 1206 LGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGN 1265

Query: 372  VGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGL---PGMKGDRGVVGE 428
             GP G  G PG  GE GP G  G  G  G  G PG PG PGP G    PG  G RG  G 
Sbjct: 1266 PGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS 1325

Query: 429  PGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGS---RGLPGVEGP 485
            PG +G QG  G +G+ G  G  G  G  GP G AG PG  GLRG  GS   +G PG  G 
Sbjct: 1326 PGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQ 1385

Query: 486  RGPPGP------------RGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAE 533
             GPPGP             G +GE+G  GL G+ GPPG                 E   +
Sbjct: 1386 AGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPG-----------------EQGEK 1428

Query: 534  MAASLKRPDS-----GATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLR 588
                L  P       G  G+PG  GP GP GPP            GLPG  GP GA G  
Sbjct: 1429 GDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPP------------GLPGPAGPKGAKGAT 1476

Query: 589  GPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIP--GVP 646
            GP G  GEKG +GPPG    G PG +  P         R   DG R       IP  G P
Sbjct: 1477 GPGGPKGEKGVQGPPGH--PGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAP 1534

Query: 647  GPPG 650
            G PG
Sbjct: 1535 GSPG 1538



 Score =  444 bits (1143), Expect = e-124
 Identities = 265/612 (43%), Positives = 312/612 (50%), Gaps = 83/612 (13%)

Query: 22   AAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGE---------PGKPGA 72
            A + GP GE+G PGPPGPPG  G+ G  G  G KG PGPPG  G+         PG+ G 
Sbjct: 933  AGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGL 992

Query: 73   PGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTA---GLP 129
            PG  G PG  G  GP G PG  GS G++G  G  G  G PGR  PGP GPPG A   G+P
Sbjct: 993  PGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGR--PGPQGPPGAAGEKGVP 1050

Query: 130  GELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDP----------LCPNACPPGRSGY 179
            GE G +GP G  G +GP G PGP GP G  G  DGD              N    G  G 
Sbjct: 1051 GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAG-EDGDKGEVGDPGQKGTKGNKGEHGPPGP 1109

Query: 180  PGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGE 239
            PG  G  G  GA G  GEPG +G +G  G +G+ G  G  GPPG  GL+G+ G  G+KGE
Sbjct: 1110 PGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGE 1169

Query: 240  KGARGLDGEPGP------------QGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGL 287
             G  G  G PGP             G  G PG  G  GPPGE G  G+ G+ G +G PG+
Sbjct: 1170 TGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGV 1229

Query: 288  PGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIP---GAKGVAGE 344
             GP+G+ G  G  G+ G PG PG KG  G  GP G+ G  G PG PG P   G +G  G 
Sbjct: 1230 KGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGA 1289

Query: 345  KGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGE------------------ 386
            KG  G  G+PGQ G+ G  G+ GPPG +G RGP G PGS G                   
Sbjct: 1290 KGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGK 1349

Query: 387  ------LGPVGSP------GLPGKLGSLGSPGL------PGLPGPPGLPGMKGDRGVVGE 428
                   GP G P      GLPG +G  G PG       PG  GPPGLPG++GD G  GE
Sbjct: 1350 TGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGE 1409

Query: 429  PGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGE---PGLRGPEGSRGLPGVEGP 485
               KG  G  G  G  GE+GE GD GLPGP+GS G  GE   PG  GP G  G PG+ GP
Sbjct: 1410 ---KGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGP 1466

Query: 486  RGPPGPRGVQGEQGATGLPGVQGPPGR-APTDQHIKQVCMRVIQEHFAEMAASLKRPDSG 544
             GP G +G  G  G  G  GVQGPPG   P  + I+ + +++ ++    +  S    +  
Sbjct: 1467 AGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDE 1526

Query: 545  ATGLPGRPGPPG 556
            A    G PG PG
Sbjct: 1527 AIPTGGAPGSPG 1538



 Score =  417 bits (1071), Expect = e-116
 Identities = 272/686 (39%), Positives = 317/686 (46%), Gaps = 78/686 (11%)

Query: 27  PPGEQGPPGPPGPPGVPGIDGID-GDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 85
           PP E+       PP        + G+ G   P GP       G          P     T
Sbjct: 309 PPLEEEQTDLQVPPTADRFQAEEYGEGGTDPPEGPYDYTYGYGDDYREETELGPALSAET 368

Query: 86  GPDGSP--GSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGL---PGELGRVGPVGD 140
              G+   G  G KG+KGEP V      PG  + GPPGP G AGL   PG  G  GPVGD
Sbjct: 369 AHSGAAAHGPRGLKGEKGEPAVLE----PGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGD 424

Query: 141 PGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGR 200
           PG RGPPG  G PG  G  G      + P     G  G    P +   +     I +  R
Sbjct: 425 PGERGPPGRAGLPGSDGAPGPPGTSLMLPFRF--GSGGGDKGPVVAAQEAQAQAILQQAR 482

Query: 201 QGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGD 260
              +G  G  G  G  G  G PG+ GL+G +G +G +G +G +GL G PG  G  G  G 
Sbjct: 483 LALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGA 542

Query: 261 QGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTG---LPGVDGRDGIPGMPGTKGEPGK 317
            G RG PG+ G KGDRG +G  G+PG  G +GDTG   LPG  G DG  G  G  G  G 
Sbjct: 543 DGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGL 602

Query: 318 PGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGP 377
           PG  G  GL G  G PGIPG  GV G  G  G  G  G  G  G PGQQG PG  G  GP
Sbjct: 603 PGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGP 662

Query: 378 QGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGD---RGVVGEPGPKGE 434
           QG  G  GE GP G PGLPG  GS G PG PG  GPPG  G +G    +G +G PGP+G 
Sbjct: 663 QGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGV 722

Query: 435 QGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGV 494
           +G  G  G  G +GE G+ G PG KG  G      ++G  G  G+PG  G  GP GP+G 
Sbjct: 723 KGVDGIRGLKGHKGEKGEDGFPGFKGDIG------VKGDRGEVGVPGSRGEDGPEGPKGR 776

Query: 495 QGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGP 554
            G  G  G PG+ G  G+                               G  GLPG PG 
Sbjct: 777 TGPTGDPGPPGLMGEKGKL------------------------------GVPGLPGYPGR 806

Query: 555 PGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR--------- 605
            GP G  G  GFPG  G +G  G+ G  G  G RGP G  G++G RG  G+         
Sbjct: 807 QGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGG 866

Query: 606 -GPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPG------------PPGPP 652
            GP+G PG  GLPG  GP  +   G  G  GPPG  G+PG PG            PPGPP
Sbjct: 867 DGPHGPPGERGLPGPQGPNGFP--GPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPP 924

Query: 653 GLPGFCEPASCTMQAGQRAFNKGPDP 678
           G+ G    A  T   G+R     P P
Sbjct: 925 GVVGPQGAAGETGPMGERGHPGPPGP 950



 Score =  414 bits (1063), Expect = e-115
 Identities = 252/579 (43%), Positives = 288/579 (49%), Gaps = 76/579 (13%)

Query: 17   GLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKP 76
            GL   A   G  G +GP GPPGP G PG  G  G  GP GPPG PGP G PG  G  G P
Sbjct: 991  GLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVP 1050

Query: 77   G------------TPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPP 123
            G              G  GL GP G PG  G  G KGE G PG +G  G +G  GPPGPP
Sbjct: 1051 GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPP 1110

Query: 124  GTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLP 183
            G  G  G+ G  G  G+PG RGP G  G  G  GT GF+          PPG  G  GLP
Sbjct: 1111 GPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNG---------PPGPIGLQGLP 1161

Query: 184  GMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGAR 243
            G  G KG  G++G  G  G  G  G  G  G  G QGPPG  G  G  G  G+ GE G+ 
Sbjct: 1162 GPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSP 1221

Query: 244  GLDGEPGPQG------------LPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPG-- 289
            G+ GEPG +G             PG PG  G +GP G+ GPKG+ G  G  G PG PG  
Sbjct: 1222 GIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEG 1281

Query: 290  -PKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPG---AKGVAGEK 345
             P+G  G  G  G DG PG PG+ G  G+ GPPG  G +G  G PG  G    KG  G+ 
Sbjct: 1282 GPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDP 1341

Query: 346  GSTGAPGKPGQMGNSGKPGQQGP------PGEVGPRGPQGLPGSRGELGPVGSPGLPGKL 399
            G+ GAPGK G +G +G  G+ GP      PG VG +G  G  G  G  GPVG PGLPG  
Sbjct: 1342 GAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLR 1401

Query: 400  GSLGS------PGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDI 453
            G  G+      PGL GL GPPG  G KGDRG+   PGP+G  G  GE            +
Sbjct: 1402 GDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGL---PGPQGSPGQKGE------------M 1446

Query: 454  GLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPG--VQGPPG 511
            G+PG  G  G  G PGL GP G +G  G  GP GP G +GVQG  G  G PG  +Q  P 
Sbjct: 1447 GIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPPGEVIQPLPI 1506

Query: 512  RAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPG 550
            + P          R++QE  A        P  GA G PG
Sbjct: 1507 QMPKKTRRSVDGSRLMQEDEA-------IPTGGAPGSPG 1538



 Score =  293 bits (751), Expect = 3e-79
 Identities = 188/417 (45%), Positives = 208/417 (49%), Gaps = 50/417 (11%)

Query: 16   LGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGK 75
            +GL       G  GE G  GP GPPG PG  G  G  G  GP GPPG  G  G PG  G+
Sbjct: 1155 IGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1214

Query: 76   PGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRV 135
            PG  G+ G+ G  G  G  G +G+KGE G PG         PGPPGP G  G  G  G  
Sbjct: 1215 PGESGSPGIQGEPGVKGPRGERGEKGESGQPGE--------PGPPGPKGPTGDDGPKGNP 1266

Query: 136  GPVGDPGRRGPPGPPGPPGPRGTIG--FHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKG 193
            GPVG PG  GPPG  GP G  G  G    DG+P  P +  PG +G  G PG  G +G  G
Sbjct: 1267 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGS--PGPTGENGPPGPLGKRGPAG 1324

Query: 194  EIGEPGRQGHKGEEGDQGELGEVGAQGP---------PGAQGLRGITGIVGDKGEKGARG 244
              G  GRQG KG +GD G +G  G  GP         PG  GLRG+ G VG +G  GA G
Sbjct: 1325 SPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATG 1384

Query: 245  LDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDG 304
              G PGP G PG PG +G  G  GE   KG  G  G  G PG  G KGD GLPG      
Sbjct: 1385 QAGPPGPVGPPGLPGLRGDAGAKGE---KGHPGLIGLIGPPGEQGEKGDRGLPGPQ---- 1437

Query: 305  IPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPG 364
              G PG KGE G PG  G  G  G PG+PG  G KG    KG+TG  G  G+ G  G PG
Sbjct: 1438 --GSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGA---KGATGPGGPKGEKGVQGPPG 1492

Query: 365  QQGPPGEVGPRGPQGLP--------GSR----GELGPV-GSPGLPGKL----GSLGS 404
              GPPGEV    P  +P        GSR     E  P  G+PG PG L    GSL S
Sbjct: 1493 HPGPPGEVIQPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDS 1549


>gi|100913220 alpha 1 type XVI collagen precursor [Homo sapiens]
          Length = 1604

 Score =  515 bits (1326), Expect = e-146
 Identities = 311/733 (42%), Positives = 356/733 (48%), Gaps = 101/733 (13%)

Query: 25   RGPPGEQGPPGPPGPPG--------------VPGIDGI-------DGDRGPKGPPGPPGP 63
            RG PGE+GP G  G PG              +PG  G+        G +GP G PGPPGP
Sbjct: 858  RGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQPGPQGPPGIPGPPGP 917

Query: 64   AGEPGKPGAPGKPGTPGADGLTGPDGS----------------------PGSIGSKGQKG 101
             G PG  G PG  G PG  GLT   GS                      PG +  KG+KG
Sbjct: 918  PGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCVQGQRAHPGYLVEKGEKG 977

Query: 102  EPGVPG--------------------------SRGFPG----RGIPGPPG---------P 122
            + G+PG                          S G PG     G+PGPPG         P
Sbjct: 978  DQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSPGLPGPPGLPGQRGEEGP 1037

Query: 123  PGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGL 182
            PG  G PG  G +GP G PG  G PG PG  G RG  G   GD   P   PPG+ GYPG 
Sbjct: 1038 PGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGL-TGDKGEPG--PPGQPGYPGA 1094

Query: 183  PGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGA 242
             G  G  G KGE G  G  G KGE G  G  G  G  GP G +G RG  G  G+KG++G 
Sbjct: 1095 TGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGERGPQGNSGEKGDQGF 1154

Query: 243  RGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGP------KGDTGL 296
            +G  G PGP G PG PG  G  GPPG    KG  G  G  G+PG PGP      +G  GL
Sbjct: 1155 QGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGLPGSPGPPGPPGIQGPAGL 1214

Query: 297  PGVDGRDGIPGM---PGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGK 353
             G+DG+DG PG+   PG  G PG  GPPG  G  G PG+PG  G  G  G  GSTG PG 
Sbjct: 1215 DGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGA 1274

Query: 354  PGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRG--ELGPVGSPGLPGKLGSLGSPGLPGLP 411
             G+ G  G  G+ GPPG VGP GP G PG  G   +G  G  G  G+ G  G PG PG P
Sbjct: 1275 EGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPP 1334

Query: 412  GPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLR 471
            G PG PG  G  G  G+ GP G+QG  G  G  G+ G  G  G  G KG AG PG PG  
Sbjct: 1335 GHPGPPGEPGTDGAAGKEGPPGKQGFYGPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKS 1394

Query: 472  GPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPP-GRAPTDQHIKQVCMRVIQEH 530
            G  G  G PG  G RG PG  G  G  G  G+PG  G         + I+Q  +++  E 
Sbjct: 1395 GSMGPVGPPGPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDER 1454

Query: 531  FAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGP 590
             A   + ++ P   A   PGRPGPPG  G PG  G PG  G+ G  G +G  G  G+RG 
Sbjct: 1455 MAYYTSRMQFPMEMAAA-PGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGL 1513

Query: 591  KGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPG 650
             G  GEKG+ G    G NGLPG    PG  GP  YG+ G  G  G  G+ GIPG PGP G
Sbjct: 1514 PGTKGEKGDIGIGIAGENGLPGP---PGPQGPPGYGKMGATGPMGQQGIPGIPGPPGPMG 1570

Query: 651  PPGLPGFCEPASC 663
             PG  G C P+ C
Sbjct: 1571 QPGKAGHCNPSDC 1583



 Score =  476 bits (1225), Expect = e-134
 Identities = 312/811 (38%), Positives = 381/811 (46%), Gaps = 194/811 (23%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 85
            GP GE+G  G  GP G+PG  G   ++G KG  G  G  G PGKPG  G+PG     G  
Sbjct: 375  GPKGEKGESGALGPSGLPGSTG---EKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPK 431

Query: 86   GPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDPGRRG 145
            G  G PG +G +G  GEPG PG  G PG G+PG PG PG  G PG  G  G  G PG+ G
Sbjct: 432  GQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPG--GPPGPKGDKGSSGIPGKEG 489

Query: 146  PPGPPGPPGPRGTIGFHDGDP--LCPNACPPGRSGYPGLPGMRGHKGAKGE----IGEPG 199
            P G PG PG +G      GDP  +CP   P G   + GLPG  G KG  G+     G+PG
Sbjct: 490  PGGKPGKPGVKG----EKGDPCEVCP-TLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPG 544

Query: 200  RQGHKGEEGD-----------------QGELGEVGAQ--GPPGAQGLRGITGIVGDKGEK 240
             QG KGE+G+                  G  G+VG+   G PG  G  G+ G+ G+KG  
Sbjct: 545  IQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPGLKGEKGNF 604

Query: 241  GARGLDGEPGPQG---------------------------------LPGAPGDQGQRGPP 267
            G  G  G PGP G                                 LPG  G++G+ GPP
Sbjct: 605  GEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKGEPGPP 664

Query: 268  --------GEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGE----- 314
                    G+AG +G +G +G  G PG PG  G TG PG+ G  G+ G  G KGE     
Sbjct: 665  GFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGC 724

Query: 315  ----------------PGKPGPPGDAGLQGL-----PGVPGIPGAKGVAGEKGSTGAPGK 353
                            PG+PGP G+ G +G+     PG PG+PG +G  G KG  G PG 
Sbjct: 725  TACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGVQGEPGP 784

Query: 354  PGQ--MGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLP 411
            PG+   G  G+PG  G PG  G  GP+G PG  GE G  GSPG+ G  G +G PG   + 
Sbjct: 785  PGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGPPG-ASVS 843

Query: 412  GPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAG--ERGELGDIGLPGPKGS-AGNPGEP 468
            GPPG  G +G  G+ G PG KG +G  GE GE     +G+L   G+PG  G   G+  +P
Sbjct: 844  GPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGAPGLWMGSSWQP 903

Query: 469  GLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQH-IKQVCMRVI 527
               GP+G  G+PG  GP G PG +GV G  G  G PG+    G  P +QH +K +C   +
Sbjct: 904  ---GPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSICGDCV 960

Query: 528  Q--------------------------EHFAEMAASLKRP------------DSGATGLP 549
            Q                          ++ A+   SL+RP            D G  G P
Sbjct: 961  QGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGCVGSP 1020

Query: 550  GRPGP------------------PGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPK 591
            G PGP                  PGPPGP G  GFPG +G  GLPG++G  G  GL G K
Sbjct: 1021 GLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGLTGDK 1080

Query: 592  GDLGEKGERGPPG-RGPNGL---------------------PGAIGLPGDPGPA----SY 625
            G+ G  G+ G PG  GP GL                     PG+ GLPG PGPA      
Sbjct: 1081 GEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGPRGER 1140

Query: 626  GRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
            G  G  GE+G  G  G PG PGPPGPPG PG
Sbjct: 1141 GPQGNSGEKGDQGFQGQPGFPGPPGPPGFPG 1171



 Score =  473 bits (1218), Expect = e-133
 Identities = 317/788 (40%), Positives = 355/788 (45%), Gaps = 154/788 (19%)

Query: 24   QRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGP---------------PGPAGEPG 68
            ++G  GE GP G PGPPG  G  GI G +G    P P               PGP+GE G
Sbjct: 600  EKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVALPGPSGEKG 659

Query: 69   KPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR----GIPGPPGPPG 124
            +PG PG  G PG  G  G  G  G  G  G  G+PG PG+ G PG     G+ GP GP G
Sbjct: 660  EPGPPGF-GLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKG 718

Query: 125  TAG---------------------LPGELGRVGP--VGDPGRRGPPGPPGPPGPRGTIGF 161
              G                      PG  G  GP  VG PG+ G PG PG  GP G  G 
Sbjct: 719  EKGDGCTACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPGLKGV 778

Query: 162  HDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGP 221
              G+P  P     G  G PG PG+ G +G  G  G PG  G KG +G  G  G  G  GP
Sbjct: 779  Q-GEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGATGPVGP 837

Query: 222  PGAQ--------GLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGD---QGQRGPPGE- 269
            PGA         G +G TG+ G  GEKG RG  GEPG    P + GD    G  G PG  
Sbjct: 838  PGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCP-SQGDLIFSGMPGAPGLW 896

Query: 270  AGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGK------------ 317
             G     G +G  GIPG PGP G  GL GV G +G+PG PG   E G             
Sbjct: 897  MGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPGNNGLPGQPGLTAELGSLPIEQHLLKSIC 956

Query: 318  ----------PG---PPGDAGLQGLPGVPGIP-----------------------GAKGV 341
                      PG     G+ G QG+PGVPG+                        G  G 
Sbjct: 957  GDCVQGQRAHPGYLVEKGEKGDQGIPGVPGLDNCAQCFLSLERPRAEEARGDNSEGDPGC 1016

Query: 342  AGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQG---------LPGSRGELGPVGS 392
             G  G  G PG PGQ G  G PG +G PG  GP GP G         LPG +GE G  G 
Sbjct: 1017 VGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGERGLTGL 1076

Query: 393  PGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVG------EPGPKGEQGASGEEGEAGE 446
             G  G+ G  G PG PG  GPPGLPG+KG+RG  G      EPGP G +G  G  G AG 
Sbjct: 1077 TGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGPPGPAGP 1136

Query: 447  RGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGP---RGVQGEQGATGL 503
            RGE G  G  G KG  G  G+PG  GP G  G PG  G  GPPGP   +G +G +G +GL
Sbjct: 1137 RGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVGSPGPPGPQAEKGSEGIRGPSGL 1196

Query: 504  PGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGE 563
            PG  GPPG                     +  A L   D G  G PG  G PGP GPPG 
Sbjct: 1197 PGSPGPPGPPGI-----------------QGPAGLDGLD-GKDGKPGLRGDPGPAGPPGL 1238

Query: 564  NGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR-GPNGLPGAIGL------ 616
             G PG  G  G PG+ GP G  G  GP G  G  G  G PG  GP G PG  G       
Sbjct: 1239 MGPPGFKGKTGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGP 1298

Query: 617  PGDPGPASY------GRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQR 670
            PG PGPA        G  G  GERG  G+ G PG PG PGPPG PG    A      G++
Sbjct: 1299 PGQPGPAGISAVGLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGTDGAAGKEGPPGKQ 1358

Query: 671  AFNKGPDP 678
             F   P P
Sbjct: 1359 GFYGPPGP 1366



 Score =  372 bits (954), Expect = e-103
 Identities = 243/589 (41%), Positives = 270/589 (45%), Gaps = 141/589 (23%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGA------------- 72
            G PG  G PG PGPPG+PG  G +G  G +G PGPPGP G PG PGA             
Sbjct: 1012 GDPGCVGSPGLPGPPGLPGQRGEEGPPGMRGSPGPPGPIGPPGFPGAVGSPGLPGLQGER 1071

Query: 73   -----------PGKPGTPGADGLTGPDGSPGS------IGSKGQKGEPGVPGSRGFPGRG 115
                       PG PG PG  G TGP G PG        GS G+KGEPG PGS G PG  
Sbjct: 1072 GLTGLTGDKGEPGPPGQPGYPGATGPPGLPGIKGERGYTGSAGEKGEPGPPGSEGLPGP- 1130

Query: 116  IPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNA---- 171
             PGP GP G  G  G  G  G  G  G+ G PGPPGPPG  G +G     P  P A    
Sbjct: 1131 -PGPAGPRGERGPQGNSGEKGDQGFQGQPGFPGPPGPPGFPGKVG--SPGPPGPQAEKGS 1187

Query: 172  ----CPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGL 227
                 P G  G PG PG  G +G  G  G  G+ G  G  GD G  G  G  GPPG +G 
Sbjct: 1188 EGIRGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGK 1247

Query: 228  RGITGIVGDKGE---------KGARGLDGEPG---PQGLPGAPGDQGQRGPPGEAGP--- 272
             G  G+ G KG+          G  G +GEPG   PQG PG PG  G  GPPG+ GP   
Sbjct: 1248 TGHPGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGI 1307

Query: 273  -----KGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQ 327
                 KGDRGA G RG+ GLPG       PG  G  G PG PGT G  GK GPPG  G  
Sbjct: 1308 SAVGLKGDRGATGERGLAGLPGQ------PGPPGHPGPPGEPGTDGAAGKEGPPGKQGFY 1361

Query: 328  GLPGVPGIPGA---KGVAGEKGSTGAPGKPGQMGNSGKPGQQGP------PGEVGPRGPQ 378
            G PG  G PGA   KG AGEKG  G PG PG+ G+ G  G  GP      PG  GP G  
Sbjct: 1362 GPPGPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSP 1421

Query: 379  GLPGSRGELG---------------------------------------------PVGSP 393
            GLPG  G +G                                             P G  
Sbjct: 1422 GLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKD 1481

Query: 394  GLPGKLGSLGSPGLPG---------LPGPPGLPGMKGDRGVVGE--------PGPKGEQG 436
            G PG+ G+ GSPGLPG         LPG  GLPG KG++G +G         PGP G QG
Sbjct: 1482 GAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGIGIAGENGLPGPPGPQG 1541

Query: 437  ASG--EEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVE 483
              G  + G  G  G+ G  G+PGP G  G PG+ G   P    G   +E
Sbjct: 1542 PPGYGKMGATGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGAMPME 1590



 Score =  358 bits (920), Expect = 7e-99
 Identities = 245/637 (38%), Positives = 300/637 (47%), Gaps = 124/637 (19%)

Query: 119 PPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNA---CPPG 175
           PP   G       L   GP G  G RG PGPPG  G +G  G +D   + P+A   C  G
Sbjct: 317 PPCVHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKGARG-NDCVRISPDAPLQCAEG 375

Query: 176 RSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVG 235
             G       +G  GA G  G PG  G KG++G++G+ G  G  G PG  G  G   ++G
Sbjct: 376 PKGE------KGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIG 429

Query: 236 DKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPG---------EAGPKGDRGAEGARGIPG 286
            KG+KG  G     GP+GL G PG  G  GPPG           GP G +G +G+ GIPG
Sbjct: 430 PKGQKGDPGF---VGPEGLAGEPGPPGLPGPPGIGLPGTPGDPGGPPGPKGDKGSSGIPG 486

Query: 287 LPGPKGDTGLPGVDGRD------------------GIPGMPGTKGEPGKPGPP-GDAGLQ 327
             GP G  G PGV G                    G+PG PG KGEPG P P  GD G+Q
Sbjct: 487 KEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPARGDPGIQ 546

Query: 328 GLPGVPGIP--GAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRG 385
           G+ G  G P      V G +    + G  G +G+ G  G  G PG  G  G +G  G+ G
Sbjct: 547 GIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGF-GLPGLPGRAGVPGLKGEKGNFG 605

Query: 386 ELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMK----GDRGVVGEPGPKGEQGASGEE 441
           E GP GSPG PG +G  G  G  G P  P  P +     GD  VV  PGP GE+G  G  
Sbjct: 606 EAGPAGSPGPPGPVGPAGIKGAKGEPCEP-CPALSNLQDGDVRVVALPGPSGEKGEPGPP 664

Query: 442 GEA--GERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGL---PGVEGPRGP-------- 488
           G    G++G+ G+ GL G KG AGNPG+PG  G  G  GL   PGV+GP GP        
Sbjct: 665 GFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQGPAGPKGEKGDGC 724

Query: 489 -------------------PGPRGVQGEQGA--------TGLPGVQGPPGRAPTDQHIKQ 521
                              PGP+G QG +G          GLPGVQGPPG          
Sbjct: 725 TACPSLQGTVTDMAGRPGQPGPKGEQGPEGVGRPGKPGQPGLPGVQGPPG---------- 774

Query: 522 VCMRVIQEHFAEMAASLKRP--DSGATGLP---GRPGPPGPPGPPGENGFPGQMGIRGLP 576
             ++ +Q         ++ P  + GA GLP   G PGP GPPGP GE G  G  G++G  
Sbjct: 775 --LKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVKGAT 832

Query: 577 GIKGPPGA--------------LGLRGPKGDLGEKGERGPPGRGPNGLPGAI---GLPGD 619
           G  GPPGA               GLRG  G+ G +GE+G PG       G +   G+PG 
Sbjct: 833 GPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGECSCPSQGDLIFSGMPGA 892

Query: 620 PGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
           PG    G + + G +GPPG+ G PG PG PG  G+PG
Sbjct: 893 PG-LWMGSSWQPGPQGPPGIPGPPGPPGVPGLQGVPG 928



 Score =  303 bits (775), Expect = 4e-82
 Identities = 220/595 (36%), Positives = 266/595 (44%), Gaps = 135/595 (22%)

Query: 199 GRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAP 258
           GR   K E G +        + PP   G R     +   G KG +G  G PGP   PG+ 
Sbjct: 295 GRISQKAERGAKVHQETAADECPPCVHGARDSNVTLAPSGPKGGKGERGLPGP---PGSK 351

Query: 259 GDQGQRG-------PPG----EAGPKGDRGAEGARGIPGLPGPKGD------------TG 295
           G++G RG       P        GPKG++G  GA G  GLPG  G+             G
Sbjct: 352 GEKGARGNDCVRISPDAPLQCAEGPKGEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKG 411

Query: 296 LPGVDGRDGIPG---MPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVA---------- 342
           +PG  GRDG PG   + G KG+ G PG  G  GL G PG PG+PG  G+           
Sbjct: 412 VPGKPGRDGRPGEICVIGPKGQKGDPGFVGPEGLAGEPGPPGLPGPPGIGLPGTPGDPGG 471

Query: 343 -----GEKGSTGAPGKPGQMGNSGKP---GQQGPPGEVGPRGPQGL---------PGSRG 385
                G+KGS+G PGK G  G  GKP   G++G P EV P  P+G          PG +G
Sbjct: 472 PPGPKGDKGSSGIPGKEGPGGKPGKPGVKGEKGDPCEVCPTLPEGFQNFVGLPGKPGPKG 531

Query: 386 ELG-PV---GSPGLPGKLGSLGSP----------------------------GLPGLPGP 413
           E G PV   G PG+ G  G  G P                            GLPGLPG 
Sbjct: 532 EPGDPVPARGDPGIQGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGR 591

Query: 414 PGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGD------------------IGL 455
            G+PG+KG++G  GE GP G  G  G  G AG +G  G+                  + L
Sbjct: 592 AGVPGLKGEKGNFGEAGPAGSPGPPGPVGPAGIKGAKGEPCEPCPALSNLQDGDVRVVAL 651

Query: 456 PGPKGSAGNPGEPGL-----RGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGL---PGVQ 507
           PGP G  G PG PG      +G  G RGL G +G  G PG  G  G  G  GL   PGVQ
Sbjct: 652 PGPSGEKGEPGPPGFGLPGKQGKAGERGLKGQKGDAGNPGDPGTPGTTGRPGLSGEPGVQ 711

Query: 508 GPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRP----DSGATGLPGRPGPPGPPGPPGE 563
           GP G           C   +Q    +MA    +P    + G  G+ GRPG PG PG PG 
Sbjct: 712 GPAGPKGEKGDGCTACPS-LQGTVTDMAGRPGQPGPKGEQGPEGV-GRPGKPGQPGLPGV 769

Query: 564 NGFPGQMGIRGLP-----GIKGPPGALGLRGPKGDLGEKGERGPPG-------RGPNGLP 611
            G PG  G++G P     G++GP G  G  G  G  G  G RGPPG       +G  G+ 
Sbjct: 770 QGPPGLKGVQGEPGPPGRGVQGPQGEPGAPGLPGIQGLPGPRGPPGPTGEKGAQGSPGVK 829

Query: 612 GAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQ 666
           GA G  G PG +  G  GRDG++G  G+ G PG  GP G  G PG C   SC  Q
Sbjct: 830 GATGPVGPPGASVSGPPGRDGQQGQTGLRGTPGEKGPRGEKGEPGEC---SCPSQ 881



 Score =  265 bits (676), Expect = 1e-70
 Identities = 161/403 (39%), Positives = 187/403 (46%), Gaps = 84/403 (20%)

Query: 25   RGPPGEQGPPGPPGPPGVPG---IDGIDGD------RGPKGPPGPPGPAGEPGKPGAPGK 75
            RGP G  G PGPPGPPG+ G   +DG+DG       RG  GP GPPG  G PG  G  G 
Sbjct: 1191 RGPSGLPGSPGPPGPPGIQGPAGLDGLDGKDGKPGLRGDPGPAGPPGLMGPPGFKGKTGH 1250

Query: 76   PGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGR----GIPGPPGPPGTAGLP-- 129
            PG PG  G  G  G PGS G  G +GEPG  G +G PG     G PGPPG PG AG+   
Sbjct: 1251 PGLPGPKGDCGKPGPPGSTGRPGAEGEPGAMGPQGRPGPPGHVGPPGPPGQPGPAGISAV 1310

Query: 130  ------GELGRVGPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLP 183
                  G  G  G  G PG+ GPPG PGPPG  GT      D       PPG+ G+ G P
Sbjct: 1311 GLKGDRGATGERGLAGLPGQPGPPGHPGPPGEPGT------DGAAGKEGPPGKQGFYGPP 1364

Query: 184  GMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKG-- 241
            G +G  GA G+ G+ G +G  G  G  G+ G +G  GPPG  G RG  G  G  G  G  
Sbjct: 1365 GPKGDPGAAGQKGQAGEKGRAGMPGGPGKSGSMGPVGPPGPAGERGHPGAPGPSGSPGLP 1424

Query: 242  ----------------------------------------------ARGLDGEPGPQGLP 255
                                                          A G  G PG  G P
Sbjct: 1425 GVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQFPMEMAAAPGRPGPPGKDGAP 1484

Query: 256  GAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEP 315
            G PG  G  G PG+ G +G +G  G RG+PG  G KGD G+ G+ G +G+PG PG +G P
Sbjct: 1485 GRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDIGI-GIAGENGLPGPPGPQGPP 1543

Query: 316  G--KPGPPGDAGLQGLPGVPGI------PGAKGVAGEKGSTGA 350
            G  K G  G  G QG+PG+PG       PG  G        GA
Sbjct: 1544 GYGKMGATGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSDCFGA 1586



 Score =  183 bits (464), Expect = 5e-46
 Identities = 128/342 (37%), Positives = 153/342 (44%), Gaps = 44/342 (12%)

Query: 341 VAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGP-------VGSP 393
           V G + S       G  G  G+ G  GPPG  G +G +G    R  + P        G  
Sbjct: 320 VHGARDSNVTLAPSGPKGGKGERGLPGPPGSKGEKGARGNDCVR--ISPDAPLQCAEGPK 377

Query: 394 GLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDI 453
           G  G+ G+LG  GLPG  G  G  G KGD G+ G PG  G  G  GE    G +G+ GD 
Sbjct: 378 GEKGESGALGPSGLPGSTGEKGQKGEKGDGGIKGVPGKPGRDGRPGEICVIGPKGQKGDP 437

Query: 454 GLPGPKGSAGNPGEPGLRGPEGSRGLPGVEG-PRGPPGPRGVQGEQGATGLPGVQGPPGR 512
           G  GP+G AG PG PGL GP G  GLPG  G P GPPGP+G +G  G  G  G  G PG+
Sbjct: 438 GFVGPEGLAGEPGPPGLPGPPGI-GLPGTPGDPGGPPGPKGDKGSSGIPGKEGPGGKPGK 496

Query: 513 APTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGI 572
                     C         E+  +L        GLPG+PGP G PG P      G  GI
Sbjct: 497 PGVKGEKGDPC---------EVCPTLPEGFQNFVGLPGKPGPKGEPGDPVPAR--GDPGI 545

Query: 573 RGLPGIKGPP-----GALGLRGPKGDLGEKGERGPPGRGPNGLPGAIGLPGDPGPASYGR 627
           +G+ G KG P       +G +      G  G+ G PG G  GLPG  G+PG         
Sbjct: 546 QGIKGEKGEPCLSCSSVVGAQHLVSSTGASGDVGSPGFGLPGLPGRAGVPG--------- 596

Query: 628 NGRDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCTMQAGQ 669
               GE+G  G AG      P G PG PG   PA      G+
Sbjct: 597 --LKGEKGNFGEAG------PAGSPGPPGPVGPAGIKGAKGE 630



 Score =  112 bits (281), Expect = 9e-25
 Identities = 74/213 (34%), Positives = 84/213 (39%), Gaps = 60/213 (28%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPK------------------------------ 55
            GP GE+G PG PGP G PG+ G+ G  G                                
Sbjct: 1404 GPAGERGHPGAPGPSGSPGLPGVPGSMGDMVNYDEIKRFIRQEIIKMFDERMAYYTSRMQ 1463

Query: 56   ---------GPPGPPGPAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVP 106
                     G PGPPG  G PG+PGAPG PG PG  G  G  G PG  G  G KGE G  
Sbjct: 1464 FPMEMAAAPGRPGPPGKDGAPGRPGAPGSPGLPGQIGREGRQGLPGVRGLPGTKGEKGDI 1523

Query: 107  GSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGD---------PGRRGPPGPPGPPGPRG 157
            G       G+PGPPGP G  G  G++G  GP+G          PG  G PG  G   P  
Sbjct: 1524 GIGIAGENGLPGPPGPQGPPGY-GKMGATGPMGQQGIPGIPGPPGPMGQPGKAGHCNPSD 1582

Query: 158  TIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKG 190
              G             P    YP +  M+G  G
Sbjct: 1583 CFG-----------AMPMEQQYPPMKTMKGPFG 1604



 Score = 53.5 bits (127), Expect = 6e-07
 Identities = 29/64 (45%), Positives = 35/64 (54%), Gaps = 4/64 (6%)

Query: 8    RGALGLLLLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEP 67
            +G  G + +G+       GPPG QGPPG     G  G  G  G +G  G PGPPGP G+P
Sbjct: 1517 KGEKGDIGIGIAGENGLPGPPGPQGPPG----YGKMGATGPMGQQGIPGIPGPPGPMGQP 1572

Query: 68   GKPG 71
            GK G
Sbjct: 1573 GKAG 1576


>gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens]
          Length = 1690

 Score =  513 bits (1320), Expect = e-145
 Identities = 330/789 (41%), Positives = 372/789 (47%), Gaps = 151/789 (19%)

Query: 24   QRGPPGEQGPPGP---PGPPGVPGIDGIDGDRG--------------------------- 53
            + GPPG  GPPGP   PGP G PG+ G DG +G                           
Sbjct: 675  RHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGG 734

Query: 54   -----PKGPPGPPGPAGEPGKPGAPGKP-----------------------GTPGADGLT 85
                 P GPPGPPG  G  G+ G PG P                       G PG  G  
Sbjct: 735  EKGSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAE 794

Query: 86   GPDGSPGSIGSKGQKGE------PGVPG------SRGFPG-------RGIPGPPGPPGTA 126
            GP G PG +G KG KG       PGVPG       RG PG        G PG PG PG  
Sbjct: 795  GPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGK 854

Query: 127  GLPGELGRVGPV---------GDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPN-ACPPGR 176
            G PG++G  GP          G PG  GPPG PG PGP G     DG P  P    P G 
Sbjct: 855  GQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFG----DDGLPGPPGPKGPRGL 910

Query: 177  SGYPGLPGMRGHKGAK---GEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGI 233
             G+PG PG RG  GA+   G  GEPG +G  G  GD+G  G  GA GPPG +G   I   
Sbjct: 911  PGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQ 970

Query: 234  VGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKG-DRGAEGARGIPGLPGPKG 292
             G  GE G  G DG PG +G  G PG QG+RG PG  GP G  RG  G +G PG PGP G
Sbjct: 971  KGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPG 1030

Query: 293  DTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAK----GVAGEKGST 348
              G  G+ G  G PG+PG +GEPG PGPPG +G+ G  G  G  G      G  G KG  
Sbjct: 1031 PPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEP 1090

Query: 349  GAPGKPGQMGNSGK---PGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSP 405
            G+PG PG  G SG+   PG QGP G  G  GP G  G  G  G  G PGL G+ G +G P
Sbjct: 1091 GSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDP 1150

Query: 406  GLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAG-----ERGELGDIGLPGPKG 460
            G  GL G PG+PG  G +G  G PG  G  G  G++G  G     + G  G +G+PG KG
Sbjct: 1151 GPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKG 1210

Query: 461  SAGNPGEPGLR--GPEGSRGLPGVEGPRGPPGPRGVQGEQGA----TGLPGVQGPPG--- 511
              G+PG PG+   GP G +G PG  G  GPPGP G  G         G PG QGPPG   
Sbjct: 1211 ERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDG 1270

Query: 512  --RAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQ 569
               AP    +               +  L R + G  GLPG PGPPGPPGPPG  GFPG 
Sbjct: 1271 PRGAPGPPGLPG-------------SVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGC 1317

Query: 570  MGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGR-GPNGLPGAIGLPGDPG-----PA 623
             G  G  G  G PG  G  G  G  GEKG  GPPGR GP GLPG  G PG P      P 
Sbjct: 1318 DGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPR 1377

Query: 624  SYGRNGRDGERGPPGVAGIPGVPGPPGP--------------PGLPGFCEPASCTMQAGQ 669
              G  G  G RGP G  G+PG+ GP GP               G+PG   P       G+
Sbjct: 1378 IPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGE 1437

Query: 670  RAFNKGPDP 678
              +  GP P
Sbjct: 1438 DGYPGGPGP 1446



 Score =  505 bits (1301), Expect = e-143
 Identities = 305/685 (44%), Positives = 349/685 (50%), Gaps = 98/685 (14%)

Query: 22   AAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGA 81
            + +RG PG  G PG PG PG PG  G  G  G  GPPGP G  G PG PG PG  G PG 
Sbjct: 827  SCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGL 886

Query: 82   DGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-RGIPGPPGPPGTAGLPGELGRVGPVGD 140
             G+ GP G  G  G  G KG  G+PG  GFPG RG PG  G PG  G PGE G  G  GD
Sbjct: 887  PGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGD 946

Query: 141  PGRRGPPGPPGPPGPRGTIGF--HDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEP 198
             G RG  G  GPPG  G +      G P  P   PPG  G+PG  G +G  G +G  GEP
Sbjct: 947  RGLRGAKGAIGPPGDEGEMAIISQKGTPGEPG--PPGDDGFPGERGDKGTPGMQGRRGEP 1004

Query: 199  GRQG----HKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGL 254
            GR G    H+GE G++G+ G  G  GPPG+ GLRG  G  G  G++G  G  G PG  G+
Sbjct: 1005 GRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGI 1064

Query: 255  PGAPGDQGQRGPP----GEAGPKGDR---------GAEGARGIPGLPGPKGDTGLPGVDG 301
             GA G +G +G P    G  GPKG+          GA G +G+PG+ GP+G  G PG  G
Sbjct: 1065 DGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPG 1124

Query: 302  RDGIP------GMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPG 355
              G P      GMPG +G+PG+ G PG  GLQG PG+PG PG KG +G  G  G  G  G
Sbjct: 1125 SSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKG 1184

Query: 356  QMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGL--PGKLGSLGSPGLPGLPGP 413
            Q G  G  G      +VGP GP G+PG +GE G  GSPG+  PG  G  G PG PG  GP
Sbjct: 1185 QKGTKGASGLH----DVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGP 1240

Query: 414  PGLPGM----------KGDRGVVGEPGPKGEQGASGEEGEAGE----RGELGDIGLPGPK 459
            PG  G            G  G  G PGP G +GA G  G  G     RGE GD GLPGP 
Sbjct: 1241 PGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPP 1300

Query: 460  GSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHI 519
            G  G PG PG +G  G  G  G +GP G PGP+G  G  G  G  G+ GPPGR       
Sbjct: 1301 GPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGR------- 1353

Query: 520  KQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIK 579
                                    G TGL   PGP G PGPP +        +   P I 
Sbjct: 1354 -----------------------KGPTGL---PGPRGEPGPPAD--------VDDCPRIP 1379

Query: 580  GPPGALGLRGPKGDLGEKGERGPPGRGPNGLP------GAIGLPGDPGPASYGRNGRDGE 633
            G PGA G+RGP+G +G  G RGP G G  G P      G  G+PG PGP   GR G  GE
Sbjct: 1380 GLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPP--GRKGDTGE 1437

Query: 634  RGPPGVAGIPGVPGPPGPPGL-PGF 657
             G PG  G PG  G PGP G  PG+
Sbjct: 1438 DGYPGGPGPPGPIGDPGPKGFGPGY 1462



 Score =  504 bits (1299), Expect = e-143
 Identities = 328/771 (42%), Positives = 378/771 (49%), Gaps = 138/771 (17%)

Query: 16   LGLCLCAAQRGPPGEQGPPGPPGPP------GVPGIDGIDGD------RGPKGPPGPPGP 63
            LGL      +G PG  G  GPPG P      G PG  G  GD      +G KG  GP GP
Sbjct: 517  LGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGP 576

Query: 64   AGEPGKPGAPGKPGTPGADGLTGP-----DGSPGSIGSKGQKGEPGVPGSRGFPGRGIPG 118
             G PG+PG+ G+ G  G  G  GP     D +PG  G  G  G PG  G  G PG G PG
Sbjct: 577  PGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPG 636

Query: 119  PPGPPGTAGLPGELGRVGPVG--------------DPGRRGPPGPPGPPGPRGTIGFHDG 164
            PPG  G  G+PG  G  GP G               PGR GPPG  GPPGP+G       
Sbjct: 637  PPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGF------ 690

Query: 165  DPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGE---PGRQGHKGEEGDQGELGE-----V 216
                     PG  G PGL G  GHKG  G  G    PG  G +G+ GD G  GE     V
Sbjct: 691  ---------PGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPV 741

Query: 217  GAQGPPGAQGLRGITGIVGDK-----GEKGARGLDGEP---GPQGLPGAPGDQGQRGPPG 268
            G  GPPG+ G+ G  GI GD      G  G RGL G P   GP+G PG PG +G  G PG
Sbjct: 742  GPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPG 801

Query: 269  EAGPKGDRGAEGARGIPGLPGPKG---DTGLPGVDGRDGIPGMPGT------KGEPGKPG 319
              G KG +G EG  G PG+PGP G   + G PG+ G+ G+PG PG+      KG+PG  G
Sbjct: 802  FLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVG 861

Query: 320  PPGDAGLQGLPGVPGIPGA------KGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVG 373
            PPG AG++GLPG+PG PGA       G+ G  G  G PG PG  G  G PG  G PGE G
Sbjct: 862  PPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERG 921

Query: 374  PRGPQGLPGSRGELGPVGSPGLP------GKLGSLGSP------------GLPGLPGPPG 415
              G +G PG++GE G  G  GLP      G  G++G P            G PG PGPPG
Sbjct: 922  KPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPG 981

Query: 416  LPGMKGDRGVVGEPGPKGEQGASGEEGEAG-ERGELGDIGLPGPKGSAGNPGEPGLRGPE 474
              G  G+RG  G PG +G +G  G  G  G  RGE G+ G PGP G  G PG  GLRG  
Sbjct: 982  DDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFI 1041

Query: 475  GSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGR-----APTDQHIKQVCMRVIQE 529
            G  GLPG +G  G PGP G  G  GA G  G +G P        P  +     C      
Sbjct: 1042 GFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGC----PG 1097

Query: 530  HFAEMAASLKRPDSGATGLPGRPGP---PGPPGPPGENGFPGQMGIRGLPGIKGPPGALG 586
            HF           SG  GLPG  GP   PG PGPPG +G PG  G  G+PG++G PG +G
Sbjct: 1098 HFGA---------SGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMG 1148

Query: 587  LRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPG---------------PASYGRNGR 630
              GP+G  G+ G  GPPG +GP+G PG  GL G  G               P   G  G 
Sbjct: 1149 DPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGL 1208

Query: 631  DGERGPPGVAGIP-----GVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGP 676
             GERG PG  GI      G  GPPGPPG  G   PA  T +A +   + GP
Sbjct: 1209 KGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGP 1259



 Score =  504 bits (1297), Expect = e-142
 Identities = 319/739 (43%), Positives = 359/739 (48%), Gaps = 114/739 (15%)

Query: 32   GPPGPPGPPGVPGIDGIDGD-----------RGPKGPPGPPGPAGEPGKPGAPGKPGTPG 80
            GPPGPPG PGV G  GI GD           RG  G PG  GP G+PG PGA G  G PG
Sbjct: 742  GPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPG 801

Query: 81   ADGLTGPDGSPGSIGSKG---------QKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGE 131
              GL GP G  G  G  G         ++G PG+PG  G PG   PG PG PG  G PG+
Sbjct: 802  FLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPG--YPGSPGAPGGKGQPGD 859

Query: 132  LGRVGPVG---------DPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPP-GRSGYPG 181
            +G  GP G          PG  GPPG PG PGP G     DG P  P    P G  G+PG
Sbjct: 860  VGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGD----DGLPGPPGPKGPRGLPGFPG 915

Query: 182  LPGMRGHKGAKG---EIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKG 238
             PG RG  GA+G     GEPG +G  G  GD+G  G  GA GPPG +G   I    G  G
Sbjct: 916  FPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPG 975

Query: 239  EKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKG-DRGAEGARGIPGLPGPKGDTGLP 297
            E G  G DG PG +G  G PG QG+RG PG  GP G  RG  G +G PG PGP G  G  
Sbjct: 976  EPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGST 1035

Query: 298  GVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVA-GEKGSTGAPGKPGQ 356
            G+ G  G PG+PG +GEPG PGPPG +G+ G  G  G  G      G  G  G PG PG 
Sbjct: 1036 GLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGC 1095

Query: 357  MGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPG------LPGKLGSLGSPGLPGL 410
             G+ G  G+QG PG  GPRG  G PG  G  GP G PG      L G+ G +G PG  GL
Sbjct: 1096 PGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGL 1155

Query: 411  PGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAG-----ERGELGDIGLPGPKGSAGNP 465
             G PG+PG  G +G  G PG  G  G  G++G  G     + G  G +G+PG KG  G+P
Sbjct: 1156 QGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDP 1215

Query: 466  GEPGLR--GPEGSRGLPGVEGPRGPPGPRGVQGEQGAT----GLPGVQGPPGR-----AP 514
            G PG+   GP G +G PG  G  GPPGP G  G         G PG QGPPG      AP
Sbjct: 1216 GSPGISPPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAP 1275

Query: 515  TDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRG 574
                +               +  L R + G  GLPG PGPPGPPGPPG  GFPG  G  G
Sbjct: 1276 GPPGLPG-------------SVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDG 1322

Query: 575  LPGIKGPPGALGLRGPKGDLGEKGERGPPGR-GPNGLPG--------------------- 612
              G  G PG  G  G  G  GEKG  GPPGR GP GLPG                     
Sbjct: 1323 QKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLP 1382

Query: 613  ----------AIGLPGDPGPASYG------RNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
                      A+GLPG  GP+  G       +GR G  G PG  G PG  G  G  G PG
Sbjct: 1383 GAPGMRGPEGAMGLPGMRGPSGPGCKGEPGLDGRRGVDGVPGSPGPPGRKGDTGEDGYPG 1442

Query: 657  FCEPASCTMQAGQRAFNKG 675
               P       G + F  G
Sbjct: 1443 GPGPPGPIGDPGPKGFGPG 1461



 Score =  503 bits (1295), Expect = e-142
 Identities = 300/689 (43%), Positives = 345/689 (50%), Gaps = 92/689 (13%)

Query: 25   RGPPGEQG-------PPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPG 77
            RGP GE+G        PGP GPPG PG+ G  G +G  G PG  G  G+PG PGA G PG
Sbjct: 480  RGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPG 539

Query: 78   TPGADGLTGPDGSPGSIGS------KGQKGEPGVPGSRGFPG-------------RGIPG 118
             PG  G +GP G+ G+ G       KG KGE G  G  GFPG             +G PG
Sbjct: 540  LPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPG 599

Query: 119  PPGP-----------PGTAGLPGELGRVGPVG-----DPGRRGPPGPPGPPGPRGTIGF- 161
            PPG            PG  G PG+ G VGP G      PG RG PG PG PG RG  G  
Sbjct: 600  PPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLK 659

Query: 162  -HDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQG 220
               GD +  N   PGR G PG  G  G KG  G  G PG  G  G +G  G  G     G
Sbjct: 660  GQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPG 719

Query: 221  PPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEA--GPKGDRGA 278
            PPG +G  G  G  G+KG           GP G PG+PG  GQ+G PG+   G  G  G 
Sbjct: 720  PPGFRGDMGDPGFGGEKGSSPV-------GPPGPPGSPGVNGQKGIPGDPAFGHLGPPGK 772

Query: 279  EGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGA 338
             G  G+PG+ GP+GD G PG +G  GIPG  G KG  G+ G  G  G+ G PG     GA
Sbjct: 773  RGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGA 832

Query: 339  KGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGK 398
             G+ G+ G  G PG PG  G  G+PG  GPPG  G +G  GLPG  G  GP G PG+PG 
Sbjct: 833  PGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGP 892

Query: 399  LGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGP 458
             G  G PG PG  GP GLPG  G  G  G+PG +G  GA GE GE G  G  GD GL G 
Sbjct: 893  FGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGA 952

Query: 459  KGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGR-APTDQ 517
            KG+ G PG+ G       +G PG  GP G  G  G +G++G  G+ G +G PGR  P   
Sbjct: 953  KGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGF 1012

Query: 518  HIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGEN------GFPGQMG 571
            H                         G  G  G+PGPPGPPGPPG        GFPG  G
Sbjct: 1013 H------------------------RGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPGLPG 1048

Query: 572  IRGLPGIKGPPGALGLRGPKGDLGEKGER----GPPGRGPNGLPGAIGLPGDPGPASYGR 627
             +G PG  GPPG  G+ G +G  G KG+     GPP  GP G PG+ G PG  G +  G 
Sbjct: 1049 DQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPP--GPKGEPGSPGCPGHFGAS--GE 1104

Query: 628  NGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
             G  G +GP G  G PG PG  GPPG PG
Sbjct: 1105 QGLPGIQGPRGSPGRPGPPGSSGPPGCPG 1133



 Score =  500 bits (1288), Expect = e-141
 Identities = 324/806 (40%), Positives = 376/806 (46%), Gaps = 198/806 (24%)

Query: 25   RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPG--------------PAGEPGK- 69
            +G  GE+GP GPPG PG PG  G DG  G KG PGPPG              P G PGK 
Sbjct: 565  KGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKA 624

Query: 70   -------------PGAPGKPGTPGADGLTGPDGSPGSIGSK--------GQKGEPGV--- 105
                         PG  G PG PG  G+ GPDG  G  G          G+ G PG    
Sbjct: 625  GPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGP 684

Query: 106  PGSRGFPG-RGIPG---------PPGPPGTAGLPGELGRVGPVGDPGRRG--------PP 147
            PG +GFPG +G PG          PG PGTA +PG  G  G +GDPG  G        PP
Sbjct: 685  PGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPP 744

Query: 148  GPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEE 207
            GPPG PG  G  G   GDP   +  PPG+ G  G+PG++G +G      +PG  G +G  
Sbjct: 745  GPPGSPGVNGQKGI-PGDPAFGHLGPPGKRGLSGVPGIKGPRG------DPGCPGAEGPA 797

Query: 208  GDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPP 267
            G  G LG  G +G  G  G  G+ G  G   E+GA G+ G+PG  G PG+PG  G +G P
Sbjct: 798  GIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQP 857

Query: 268  GEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGR---DGIPGMPGTKGEPGKPGPPGDA 324
            G+ GP G  G +G  G+PG PG  G  GLPG+ G    DG+PG PG KG  G PG PG  
Sbjct: 858  GDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFP 917

Query: 325  GLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPG------------QQGPPGEV 372
            G +G PG  G PGAKG  GEKG +G PG  G  G  G  G            Q+G PGE 
Sbjct: 918  GERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEP 977

Query: 373  GPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGL----------PGLPGPPGLPGMKGD 422
            GP G  G PG RG+ G  G  G  G+ G  G PG           PG PGPPG PG  G 
Sbjct: 978  GPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGL 1037

Query: 423  RGVVGEPGPKGEQGA---------SGEEGEAGERGELGD----IGLPGPKGSAGNPGEPG 469
            RG +G PG  G+QG          SG +G  G +G  GD     G PGPKG  G+PG PG
Sbjct: 1038 RGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEPGSPGCPG 1097

Query: 470  LRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQE 529
              G  G +GLPG++GPRG PG  G  G  G  G PG  G PG                  
Sbjct: 1098 HFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPG------------------ 1139

Query: 530  HFAEMAASLKRPDSGATGLPGRPGPPGP---------PGPPGENGFPGQMGIRGLPGIK- 579
                             G PG  G PGP         PGPPG  G  G  G+ GL G+K 
Sbjct: 1140 ---------------LRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKG 1184

Query: 580  -------------GPPGALGLRGPKGDLGEKGERG--PPG----RGPNGLPGAIGLPG-- 618
                         GPPG +G+ G KG+ G+ G  G  PPG    +GP G PG+ G PG  
Sbjct: 1185 QKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPA 1244

Query: 619  -----------DPG-PASYGRNGRDGERGPPGV----------------AGIPGVPGPPG 650
                       DPG P   G  G DG RG PG                  G+PG PGPPG
Sbjct: 1245 GATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPG 1304

Query: 651  PPGLPGFCEPASCTMQAGQRAFNKGP 676
            PPG PG+     C  + GQ    KGP
Sbjct: 1305 PPGPPGYKGFPGCDGKDGQ----KGP 1326



 Score =  488 bits (1256), Expect = e-138
 Identities = 324/793 (40%), Positives = 371/793 (46%), Gaps = 167/793 (21%)

Query: 8    RGALGLL----LLGLCLCAAQRGPPGEQGPPGPP-----------GPPGVPGIDGIDGDR 52
            +G LGL+    L GL      +G PG +G PGPP           GPPG PG  G  G+ 
Sbjct: 325  KGELGLVGDPGLFGLI---GPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGET 381

Query: 53   GPKGPPGPPGPAGEPGK-----------PGAPGKPGTPGADGLTG-PDGSPGSIGSKGQK 100
            G  GPPGPPG  G PG+            G PG PG PG  G+ G PD +PG  G  G  
Sbjct: 382  GDVGPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSP 441

Query: 101  GEPGVPGSRGFPG-------------RGIPGPPGPPGTAGLPGELGRVGPVG-DPGRRGP 146
            G PG PG +G PG             +GI G  GPPG  G  GE G  G    +PG  GP
Sbjct: 442  GLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGP 501

Query: 147  PGPPGPPGPRGTIG--------FHDGDPLCPNACPPGRSGYPGLPG-------------- 184
            PGPPG PG +G+ G           GDP      PPG  G PGLPG              
Sbjct: 502  PGPPGLPGRQGSKGDLGLPGWLGTKGDP-----GPPGAEGPPGLPGKHGASGPPGNKGAK 556

Query: 185  -------MRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPG-----AQGLRGITG 232
                   ++GHKG +G  G PG  G  G  G  G  GE G  GPPG       G +G  G
Sbjct: 557  GDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPG 616

Query: 233  IVGDKGEKG-----ARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDR--------GAE 279
             +G  G+ G       G  G PG +G PG PG  G RGP G  G KGD         G  
Sbjct: 617  PLGPPGKAGPVGPPGLGFPGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRH 676

Query: 280  GARGIPGLPGPK---GDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGV---- 332
            G  G  G PGPK   G  G PG+ G DG  G PGT G    PGPPG  G  G PG     
Sbjct: 677  GPPGFDGPPGPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEK 736

Query: 333  -------PGIPGAKGVAGEKGSTGAP-----GKPGQMGNSGKPGQQGP---PGEVGPRGP 377
                   PG PG+ GV G+KG  G P     G PG+ G SG PG +GP   PG  G  GP
Sbjct: 737  GSSPVGPPGPPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGP 796

Query: 378  QGLPGSRGELGP------VGSPGLPGKLGSL---------GSPGLPGLPGPPGLPGMKGD 422
             G+PG  G  GP       G PG+PG  G           G PGLPG PG PG PG KG 
Sbjct: 797  AGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQ 856

Query: 423  RGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGV 482
             G VG PGP G +G  G  G  G  G  G  G+PGP G  G PG PG +GP G  G PG 
Sbjct: 857  PGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGF 916

Query: 483  EGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPD 542
             G RG PG  G  G +G  G  G+ G PG    D+ ++               A     D
Sbjct: 917  PGERGKPGAEGCPGAKGEPGEKGMSGLPG----DRGLR-----------GAKGAIGPPGD 961

Query: 543  SGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGP----KGDLGEKG 598
             G   +  + G PG PGPPG++GFPG+ G +G PG++G  G  G  GP    +G+ GEKG
Sbjct: 962  EGEMAIISQKGTPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKG 1021

Query: 599  ERGPPG----RGPNGLPGAIGLPGDPG-------PASYGRNGRDGERGPPGVAGIP---- 643
            + GPPG     G  GL G IG PG PG       P   G +G DG RGP G  G P    
Sbjct: 1022 QPGPPGPPGPPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHF 1081

Query: 644  GVPGPPGPPGLPG 656
            G PGP G PG PG
Sbjct: 1082 GPPGPKGEPGSPG 1094



 Score =  469 bits (1206), Expect = e-132
 Identities = 314/799 (39%), Positives = 362/799 (45%), Gaps = 167/799 (20%)

Query: 18  LCLCAAQ---RGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPG 74
           +C C  +   RGPPG  GP GP GP G PG  G+ G++G +G  GPPG AG+ G  G  G
Sbjct: 54  VCHCVPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTG 113

Query: 75  KPGTPGADGLTG------PDGSPGSIGSKGQKGEPGVPGSRGFPG--------------- 113
            PG PG DG+ G      P G PG  G  G +G+PG PG RG  G               
Sbjct: 114 VPGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKG 173

Query: 114 ---------RGIPGPPGPPGTAGLPGELGRVGPVG------DPGRRGPPGPPGPPGPRGT 158
                    +GI G  G PG  GLPG  G  GP G      +PG  GPPG PG PG +G 
Sbjct: 174 NSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGN 233

Query: 159 IGF----HDGDP---------------LCPNACP----------PGRSGYPGLPGMRGHK 189
            G       GDP                 P+ C           PG  G PG PG +G  
Sbjct: 234 PGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGES 293

Query: 190 G--AKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDG 247
           G  AKGE G PG  G +G+ G  G  G  G +G  G  G  G+ G++G KG+ G RG  G
Sbjct: 294 GIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPG 353

Query: 248 EPG-----------PQGLPGAPGDQGQRGPPGEAGPKG--DRGAEGARGIPGLPGPKGDT 294
            PG           P G PG PG  G+ G  G  GP G   R  E   G+ G PGP+G  
Sbjct: 354 PPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGFP 413

Query: 295 GLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLPGVPGIPGAK------GVAGEKGST 348
           GLPG+ G  GIPG P +   PGKPG PG  GL G PG+ G+PG+       G  G +G  
Sbjct: 414 GLPGLPGEAGIPGRPDSA--PGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIK 471

Query: 349 GAPGKPGQMGNSGKPGQQG----PPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGS 404
           G  G PG  G  G+ G +G     PG +GP GP GLPG +G  G +G   LPG LG+ G 
Sbjct: 472 GKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLG---LPGWLGTKGD 528

Query: 405 PGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGN 464
           PG PG  GPPGLPG  G  G  G  G KG+   S  +G  GERG  G  G PG  GS G 
Sbjct: 529 PGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGR 588

Query: 465 PGE-----------------PGLRGPEGSRGLPGVEGPRGPPG-----PRGVQGEQGATG 502
            G                  PG +G  G  G PG  GP GPPG     P G +G  G  G
Sbjct: 589 DGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGHPGVPG 648

Query: 503 LPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPG 562
            PGV+GP G                      +        S     PGR GPPG  GPPG
Sbjct: 649 HPGVRGPDG----------------------LKGQKGDTISCNVTYPGRHGPPGFDGPPG 686

Query: 563 ENGFPGQMGIRGLPG---------------IKGPPGALGLRGPKGDLGEKGER--GPPGR 605
             GFPG  G  GL G               I GPPG  G  G  G  GEKG    GPPG 
Sbjct: 687 PKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPG- 745

Query: 606 GPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGI------PGVPGPPGPPGLPGFCE 659
            P G PG  G  G PG  ++G  G  G+RG  GV GI      PG PG  GP G+PGF  
Sbjct: 746 -PPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLG 804

Query: 660 PASCTMQAGQRAFNKGPDP 678
                 + G   F   P P
Sbjct: 805 LKGPKGREGHAGFPGVPGP 823



 Score =  462 bits (1188), Expect = e-130
 Identities = 274/628 (43%), Positives = 316/628 (50%), Gaps = 107/628 (17%)

Query: 22   AAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGA 81
            A  +G PG  G PG  GPPG+PGI G  GD G  GPPGP GP G PG PG PG+ G PGA
Sbjct: 866  AGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPGA 925

Query: 82   DGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG-------------RGIPGPPGPPGTAGL 128
            +G  G  G PG  G  G  G+ G+ G++G  G             +G PG PGPPG  G 
Sbjct: 926  EGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQKGTPGEPGPPGDDGF 985

Query: 129  PGELG---------------RVGPVG----DPGRRGPPGPPGPPGPRGTIGFHD--GDPL 167
            PGE G               R GP G    +PG +G PGPPGPPGP G+ G     G P 
Sbjct: 986  PGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPG 1045

Query: 168  CP-NACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQG 226
             P +   PG  G PG  G+ G +G KG  G+P    H G  G +GE G  G  G  GA G
Sbjct: 1046 LPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPA--SHFGPPGPKGEPGSPGCPGHFGASG 1103

Query: 227  LRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPG 286
             +G+ GI G +G  G  G  G  GP G PG  G  G RG PGE G  G RG +G  GIPG
Sbjct: 1104 EQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQGDPGIPG 1163

Query: 287  LPGPKGDTGLPGVDGRDGIPGMPGTKGEPG--KPGPPGDAGLQGLPGVPGIPGAKGVA-- 342
             PG KG +G PG++G  G+ G  GTKG  G    GPPG  G+ GL G  G PG+ G++  
Sbjct: 1164 PPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLKGERGDPGSPGISPP 1223

Query: 343  GEKGSTGAPGKPGQMG----------------NSGKPGQQGPPGEVGPR---GPQGLPGS 383
            G +G  G PG PG  G                + G PG QGPPG  GPR   GP GLPGS
Sbjct: 1224 GPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGS 1283

Query: 384  ----RGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASG 439
                RGE G  G PG PG  G  G PG  G PG  G  G KG  G  G  GP G  G  G
Sbjct: 1284 VDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPG 1343

Query: 440  EEGEAGERGELGDIGLPGPKGSAGN-------------PGEPGLRGPEGSRGLPGVEGPR 486
            E+G  G  G  G  GLPGP+G  G              PG PG+RGPEG+ GLPG+ GP 
Sbjct: 1344 EKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPS 1403

Query: 487  GP--PGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSG 544
            GP   G  G+ G +G  G+PG  GPPGR                           + D+G
Sbjct: 1404 GPGCKGEPGLDGRRGVDGVPGSPGPPGR---------------------------KGDTG 1436

Query: 545  ATGLPGRPGPPGPPGPPGENGF-PGQMG 571
              G PG PGPPGP G PG  GF PG +G
Sbjct: 1437 EDGYPGGPGPPGPIGDPGPKGFGPGYLG 1464


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
            sapiens]
          Length = 1424

 Score =  513 bits (1320), Expect = e-145
 Identities = 313/752 (41%), Positives = 367/752 (48%), Gaps = 131/752 (17%)

Query: 26   GPPGEQGPPGPPGPPGV--PGIDGIDGDRGPKGPPGPPGPAGEPGK-------PGAPGKP 76
            G PG  GP GP GPPG    G  G+ G +G  G PGPPG AG  G+       PG PG P
Sbjct: 602  GSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPP 661

Query: 77   GTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVG 136
            G PG  G  GP G PGS+G  G  G PG  G  G PG G PGPPGP G  G PG  G +G
Sbjct: 662  GPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLG 721

Query: 137  PVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIG 196
              G  G  G PG PG PG +G           P    PG  G PG PG RG+ G  GEIG
Sbjct: 722  CPGKMGEPGLPGKPGLPGAKGE----------PAVAMPGGPGTPGFPGERGNSGEHGEIG 771

Query: 197  ---------EPGRQGHKGEEGDQGELGEVGAQGPPG--------AQGLRGITGIVGDKGE 239
                      PG +G  G  GD G+ G  G QGPPG        AQGL G+ G+ G +G 
Sbjct: 772  LPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGR 831

Query: 240  KGARGLDGEPGPQGL-----------PGAPGDQGQRGP---------PGEAGPKGDRGAE 279
            +G  G  G+PG  GL           PG PG QG+ GP         PG  GP G+ G  
Sbjct: 832  RGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVI 891

Query: 280  GARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLP--------- 330
            G  G PG  GP G  G PG  G+ G PG+PG KG+ G PG  G+ G +G P         
Sbjct: 892  GMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVI 951

Query: 331  ---GVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPP---GEVGPRGPQGLPGSR 384
               G PG+ G  G  GEKG+ G PG PG  G  G PG  GPP   G++G  G  G PG R
Sbjct: 952  GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLR 1011

Query: 385  ---GELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVG-----EPGPKGEQG 436
               G +G +G PG  GK G+LG PG  G PG PG+ G++GD+G  G      PGP G  G
Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071

Query: 437  ASGEEGEAGERGELGDIGLP------GPKGSAGNPGEP------------------GLRG 472
              G  G+ G++GE+G  G P      GP+G+ G+PG P                  GL G
Sbjct: 1072 DPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLG 1131

Query: 473  PEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPG-----RAPTDQHIKQVCMRVI 527
            P G RG PG+ G  G PGP G++G+QG  G+PG  G  G     RAP             
Sbjct: 1132 PPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAK 1191

Query: 528  QEHFA--------EMAASLKRPDSGATGLPGRPGPPGPPGP--PGENGFPGQMGIRGLPG 577
             +  A           A       G TG+ G PGPPG PG   PG+ G  G  G RG PG
Sbjct: 1192 GDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPG 1251

Query: 578  IKGPPG-----ALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPG-------PAS 624
              GPPG      +G++G KG +G  G +GPPG  G  G PG +G PG PG       P  
Sbjct: 1252 APGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGF 1311

Query: 625  YGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
             G  G  GE+G PG  G  G PGP GP G PG
Sbjct: 1312 QGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG 1343



 Score =  489 bits (1259), Expect = e-138
 Identities = 325/771 (42%), Positives = 359/771 (46%), Gaps = 144/771 (18%)

Query: 7    DRGALGLLLLGLCLCAAQRGPPGEQGPPGPPGPP-------GVPGIDGIDGDRGPKGPPG 59
            +RG  G   +G        G PG  G PGPPGPP       G PG  G+ G  G  G PG
Sbjct: 405  ERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPG 464

Query: 60   PPGPAGEPGK-----PGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG- 113
              GP GEPG      P  PG PG PG  GL G  G PG  G+ G KG PG PG+ G PG 
Sbjct: 465  VDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGF 524

Query: 114  RGIPGPPGPPGTAGLPGEL----GRVGPVGDPGRRGPPGP------PGPPGPRGTIGFHD 163
             G PG  G PG  G  GE     G+VG  GDPG RG PG       PG PG +G  G   
Sbjct: 525  PGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKG 584

Query: 164  GDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPG 223
               L   +   G  G PG PG  G  G  G  G PG  G +GE G QG  G  GA GPPG
Sbjct: 585  ELAL---SGEKGDQGPPGDPGSPGSPGPAGPAGPPG-YGPQGEPGLQGTQGVPGAPGPPG 640

Query: 224  AQGLRGITGI-VGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGAR 282
              G RG   +     G  G  G  G PGPQG PG PG  G+ G PG  GP G+ G  G  
Sbjct: 641  EAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI- 699

Query: 283  GIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAG-----LQGLPGVPGIPG 337
            G PG PGPKGD G PG  G  G PG  G  G PGKPG PG  G     + G PG PG PG
Sbjct: 700  GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759

Query: 338  AKGVAGEKGSTGAPGKPGQMGNSGK---------PGQQGPPGE--------VGPRGPQGL 380
             +G +GE G  G PG PG  G  G          PGQ GPPGE         GPRG QGL
Sbjct: 760  ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819

Query: 381  P---------GSRGELGPVGSPGLP-----------------------GKLGSLGSPGLP 408
            P         G RG+ GP G PG+P                       G LG  G PG P
Sbjct: 820  PGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNP 879

Query: 409  GL---------------------PGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGER 447
            G+                     PGPPG PG  G RG  G PG KG++G  G +GE G++
Sbjct: 880  GILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDK 939

Query: 448  GE---------LGDIGLPGPKGSAGNPGEPGLRGPEGS---RGLPGVEGPRGPPGPRGVQ 495
            G          +GD G PG KG AGNPGE G RG  G    +GL G+ GP GPPGPRG  
Sbjct: 940  GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL 999

Query: 496  GEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPP 555
            G  G  G PG++G PG                      M     +   G  G PGR G P
Sbjct: 1000 GSTGNPGEPGLRGIPG------------------SMGNMGMPGSKGKRGTLGFPGRAGRP 1041

Query: 556  GPPGPPGENGFPGQMGIR--GLPGIKGPPGALGLRGPKGDLGEKGERGPPG-------RG 606
            G PG  G  G  G+ G      PG  GP G  GL G  G  GE G+ GPPG        G
Sbjct: 1042 GLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEG 1101

Query: 607  PNGLPGAIGLPGDPGP-ASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
              G PG+ GLPG PGP    G  G  G  GPPG+ G PG+PG PG PG  G
Sbjct: 1102 APGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMG 1152



 Score =  488 bits (1256), Expect = e-138
 Identities = 303/687 (44%), Positives = 340/687 (49%), Gaps = 107/687 (15%)

Query: 24   QRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPG--APGKPGTPGA 81
            +RG  GE G  G PG PG+PG  G +G  GP+G PG PGP GE G PG    G  G  G 
Sbjct: 760  ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819

Query: 82   DGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDP 141
             GL G  G  G  G  G KG+PG+P   G    G PG  G PG  G  GE+G +G  G P
Sbjct: 820  PGLNGLKGQQGRRGKTGPKGDPGIP---GLDRSGFPGETGSPGIPGHQGEMGPLGQRGYP 876

Query: 142  GRRGPPGPPGPPGPRGTIGFHDGDPLCPNAC-PPGRSGYPGLPGMRGHKGAKGEIGEPGR 200
            G  G  GPPG  G  G +GF       P A  PPG  G PG PG RG  G  G  G+ G 
Sbjct: 877  GNPGILGPPGEDGVIGMMGF-------PGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGT 929

Query: 201  QGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGD 260
             G KGE+GD+G  G        G +G  G+ G  G+ GEKG RG+ G PG +GL G PG 
Sbjct: 930  PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989

Query: 261  QGQRGPPGEAGPKGDRGAEGARGIP------GLPGPKGDTGLPGVDGRDGIPGMP----- 309
             G  GP G+ G  G+ G  G RGIP      G+PG KG  G  G  GR G PG+P     
Sbjct: 990  AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL 1049

Query: 310  -GTKGEPG-----KPGPPGDAGLQGLP------GVPGIPGAKGVAGEKGSTGAPGKPGQM 357
             G KGEPG     +PGPPG  G  GLP      G  G PG  G  G  G  GAPG PG  
Sbjct: 1050 QGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSP 1109

Query: 358  GNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGP---- 413
            G  GKPG  G  G  G +G  G PG RG  G  G PG PG +G  G  G  G+PGP    
Sbjct: 1110 GLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEK 1169

Query: 414  ---------------PGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGP 458
                           PG  G KGDRG  G PG  G +GA    G+AG RG  G  G PGP
Sbjct: 1170 GETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAM---GDAGPRGPTGIEGFPGP 1226

Query: 459  KGSAGN--PGEPGLRGPEGSRGLPGVEGPRGPPGPR--GVQGEQGATGLPGVQGPPGRAP 514
             G  G   PG+ G RGP GSRG PG  GP GPPG    G++G++G+ G PG +GPPG A 
Sbjct: 1227 PGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTA- 1285

Query: 515  TDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRG 574
                                         G  G PGR G PG PG PG  G PG  G  G
Sbjct: 1286 -----------------------------GDMGPPGRLGAPGTPGLPGPRGDPGFQGFPG 1316

Query: 575  LPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGPASYGRNGRDGE 633
            + G KG PG LG  GP G +G K   GPPG RG  G    I LPG PGP           
Sbjct: 1317 VKGEKGNPGFLGSIGPPGPIGPK---GPPGVRGDPGTLKIISLPGSPGPP---------- 1363

Query: 634  RGPPGVAGIPGVPGPPGPPGLPGFCEP 660
             G PG  G+ G PGPPGPPG  G C P
Sbjct: 1364 -GTPGEPGMQGEPGPPGPPGNLGPCGP 1389



 Score =  484 bits (1245), Expect = e-136
 Identities = 308/736 (41%), Positives = 372/736 (50%), Gaps = 127/736 (17%)

Query: 17  GLCLCAAQRGPPGEQGPPGPPGPPGVPGI---DGIDGDRGPKGPPGPPGPAGE------- 66
           G C C   +G  GE+G PGPPG PG  G    +G+ G +GPKG PG PG  G        
Sbjct: 37  GQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGIS 96

Query: 67  --PGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----------- 113
             PG  G+PG PGTPG  G  G  G PG  GSKG++G PG+PG+ G+PG           
Sbjct: 97  GLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQK 156

Query: 114 -------------RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIG 160
                        +G PG PG PG  GLPG  G  GPVG PG  G  G PG  GPRG  G
Sbjct: 157 GAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216

Query: 161 FHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEI-----GEPGRQGHKGEEGDQGELGE 215
            H G+ +       G  G  G+ G+ G  G  G +     G   R   KGE+GD+G +GE
Sbjct: 217 -HMGERVI------GHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGE 269

Query: 216 VGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQ---GQRGPPGEAGP 272
               GPPG  GL G      +KG  G  GL G+PG  G+PG PG +   G RG PG  G 
Sbjct: 270 ---PGPPGPSGLPG-ESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGE 325

Query: 273 KGDRGAEGARGIPGLPGP---------KGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGD 323
            G +G +G  G PG  GP         KGD G PG  G  G  G  G  G PG PG PG 
Sbjct: 326 DGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGS 385

Query: 324 A--GLQGLPGVPGIPGAKGVAGEKG--STGAPGKPGQMGNSGKPGQQGPPGEVGP----R 375
           +  GL+G PG PG+ G+KG  G  G  + G PG PG  G+ G PG  GPPG  G     +
Sbjct: 386 SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRK 445

Query: 376 GPQGLPGSRGELGPVGSPGLPGKLGSLGSPGL-----PGLPGPPGLPGMKGDRGVVGEPG 430
           GP   PG  G  G +GSPG+PG  G  G PGL     P +PGPPGLPG+ G  GV G P 
Sbjct: 446 GP---PGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIP- 501

Query: 431 PKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRG----PEGSRGLPGVEGPR 486
             G QGA+G +G  G  G  G  G PG  G+ G+PG  G +G    PEG  G+PG  G R
Sbjct: 502 --GRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLR 559

Query: 487 GPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGAT 546
           G PG +G+ G  G  G+ G+ GP G                     E+A S ++ D G  
Sbjct: 560 GQPGRKGLDGIPGTPGVKGLPGPKG---------------------ELALSGEKGDQGPP 598

Query: 547 GLPGRPGPPGPPGPPGENGF--PGQMGIRGLPGIKGPPGALGLRGPKGDL-------GEK 597
           G PG PG PGP GP G  G+   G+ G++G  G+ G PG  G  GP+G+L       G  
Sbjct: 599 GDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPP 658

Query: 598 GERGPPG----RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPG 653
           G  GPPG    +GP G+PG++G  GDP     G  G DGE G PG+ G PG PGP G  G
Sbjct: 659 GPPGPPGHPGPQGPPGIPGSLGKCGDP-----GLPGPDGEPGIPGI-GFPGPPGPKGDQG 712

Query: 654 LPGFCEPASCTMQAGQ 669
            PG      C  + G+
Sbjct: 713 FPGTKGSLGCPGKMGE 728



 Score =  476 bits (1225), Expect = e-134
 Identities = 310/765 (40%), Positives = 374/765 (48%), Gaps = 144/765 (18%)

Query: 15  LLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRG-----------PKGPPGPPGP 63
           L+G+  C+  +G  G  G PG  G PG+PG  G+ G +G            KG PG PG 
Sbjct: 119 LVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGA 178

Query: 64  AGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPG--VPGSRGFPG-RGIPGPP 120
            G  G PG PG PG  G  G  G  G PG++G +G KG  G  V G +G  G +G+ GPP
Sbjct: 179 PGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPP 238

Query: 121 GPPGT-----------AGLPGELGRVGPVGDPGRRGP-----------PGPPGPPGPRGT 158
           GPPGT             L GE G  G +G+PG  GP            G PG PG +G 
Sbjct: 239 GPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGK 298

Query: 159 IGFHDGDPLCPNA-CPPGRSGYPGLPGMRGHKGAKGEIGEPGRQG---------HKGEEG 208
            G  DG P  P +    G  G+PGL G  G KG KG+IG PG +G          KG+EG
Sbjct: 299 PG-KDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEG 357

Query: 209 DQGELGEVGAQGP-----------------PGAQGLRGITGIVGDKGEKG-----ARGLD 246
             G  G  GA+GP                 PG +G  G  G+ G KGE+G     A G  
Sbjct: 358 TPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTP 417

Query: 247 GEPGPQGLPGAPGDQGQRGPPGE----AGPKGDRGAE---GARGIPGLPGPKGDTGL--- 296
           G PG  G PG PG  G  GPPG+     GP GD G     G+ GIPG+ GPKG+ GL   
Sbjct: 418 GSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCT 477

Query: 297 -----PGVDGRDGIPGMPGTKGEPGK---------PGPPGDAGLQGLPGVPGIPGAKGVA 342
                PG  G  G+PG+ G KG PG+         PG PG+ GL G PG PG  G  G+ 
Sbjct: 478 QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK 537

Query: 343 GEKGST-------GAPGKPGQMGNSGKPGQQGPPGE------VGPRGPQGLPGSRGELGP 389
           GEKG T       G PG PG  G  G+ G  G PG        GP+G   L G +G+ GP
Sbjct: 538 GEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGP 597

Query: 390 VGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGE--------- 440
            G PG PG  G  G  G PG  GP G PG++G +GV G PGP GE G  GE         
Sbjct: 598 PGDPGSPGSPGPAGPAGPPGY-GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPG 656

Query: 441 -EGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGV--EGPRGPPGPRGVQGE 497
             G  G  G  G  G PG  GS G  G+PGL GP+G  G+PG+   GP GP G +G  G 
Sbjct: 657 PPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGT 716

Query: 498 QGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGP 557
           +G+ G PG  G PG                      +  +   P   A  +PG PG PG 
Sbjct: 717 KGSLGCPGKMGEPGLPGK----------------PGLPGAKGEP---AVAMPGGPGTPGF 757

Query: 558 PGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGE---KGERGPPGRGPNGLPGAI 614
           PG  G +G  G++G+ GLPG+ G PG  GL GP+GD G+    GE+GPPGR   G  GA 
Sbjct: 758 PGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQ 817

Query: 615 GLPGDPG-PASYGRNGRDGERGPPGVAGI--PGVPGPPGPPGLPG 656
           GLPG  G     GR G+ G +G PG+ G+   G PG  G PG+PG
Sbjct: 818 GLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPG 862



 Score =  446 bits (1146), Expect = e-125
 Identities = 279/664 (42%), Positives = 326/664 (49%), Gaps = 131/664 (19%)

Query: 24   QRGPPGEQGPPG-----PPGPPGVPGIDGIDGDRG------PKGPPGPPG---------- 62
            Q GPPGEQGPPG     P G  G+PG++G+ G +G      PKG PG PG          
Sbjct: 796  QPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGET 855

Query: 63   -------------PAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSR 109
                         P G+ G PG PG  G PG DG+ G  G PG+IG  G  G PG PG R
Sbjct: 856  GSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQR 915

Query: 110  GFPG-------------------RGIPGP------------PGPPGTAGLPGELGRVGPV 138
            G PG                   +G PGP            PG  G AG PGE G  G  
Sbjct: 916  GSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVP 975

Query: 139  GDPGRRGP---PGPPGPPGPRGTIGFHDGDPLCPNACP-PGRSGYPGLPGMRGHKGAKGE 194
            G PG +G    PGP GPPGPRG +G   G+P  P     PG  G  G+PG +G +G  G 
Sbjct: 976  GMPGLKGLKGLPGPAGPPGPRGDLG-STGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGF 1034

Query: 195  IGEPGRQGHKGEEGDQGELGEVGAQ-----GPPGAQGLRGITGIVGDKGEKGARGLDGEP 249
             G  GR G  G  G QG+ GE G       GPPG  G  G+ G +G KGE G  G  G  
Sbjct: 1035 PGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHL 1094

Query: 250  GPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMP 309
            GP G  GAPG  G  G PG+ GP GD G +G +G+ G PG +G  GLPG  G  G  G+ 
Sbjct: 1095 GPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIR 1154

Query: 310  GTKGEPGKPGPPGDAGLQGL----PGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQ 365
            G +G  G PGP G+ G  GL    PG  G PGA+G  G++G+ G PG PG+ G  G  G 
Sbjct: 1155 GDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGP 1214

Query: 366  QGPPGEVGPRGPQGLPGS--RGELGPVGSPGLPGKLGSLGSPGLPGLPGPPG--LPGMKG 421
            +GP G  G  GP GLPG+   G+ G  G PG      S GSPG PG PGPPG  + G+KG
Sbjct: 1215 RGPTGIEGFPGPPGLPGAIIPGQTGNRGPPG------SRGSPGAPGPPGPPGSHVIGIKG 1268

Query: 422  DRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGL-- 479
            D+G +G PGPKG  G +G+ G  G  G  G  GLPGP+G  G  G PG++G +G+ G   
Sbjct: 1269 DKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLG 1328

Query: 480  ----PGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMA 535
                PG  GP+GPPG RG  G      LPG  GPPG                        
Sbjct: 1329 SIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGT----------------------- 1365

Query: 536  ASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLG 595
                         PG PG  G PGPPG  G  G  G RG PG  G PG  G  G KG+ G
Sbjct: 1366 -------------PGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKG 1412

Query: 596  EKGE 599
             KGE
Sbjct: 1413 SKGE 1416



 Score =  434 bits (1115), Expect = e-121
 Identities = 282/669 (42%), Positives = 337/669 (50%), Gaps = 121/669 (18%)

Query: 8    RGALGLLLLGLCLCAAQRGPPGEQGPPGPPGPPGV-----------PGIDGIDGDRGP-- 54
            RGA GL   GL     Q+G  G+ GP G PG PG+           PGI G  G+ GP  
Sbjct: 814  RGAQGLP--GLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLG 871

Query: 55   -KGPPGPPGPAGEPGK---------------PGAPGKPGTPGADGLTGPDGSPGSIGSKG 98
             +G PG PG  G PG+               PG PG PGTP      G  GSPG  G KG
Sbjct: 872  QRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTP------GQRGSPGIPGVKG 925

Query: 99   QKGEPGVPGSRGFPGR----------GIPGPPGPPGTAGLPGELGRVGPVGDP---GRRG 145
            Q+G PG  G +G  G           G  G PG  G AG PGE G  G  G P   G +G
Sbjct: 926  QRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKG 985

Query: 146  PPGPPGPPGPRGTIGFHDGDPLCPNACP-PGRSGYPGLPGMRGHKGAKGEIGEPGRQGHK 204
             PGP GPPGPRG +G   G+P  P     PG  G  G+PG +G +G  G  G  GR G  
Sbjct: 986  LPGPAGPPGPRGDLG-STGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLP 1044

Query: 205  GEEGDQGELGEVG-----AQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPG 259
            G  G QG+ GE G       GPPG  G  G+ G +G KGE G  G  G  GP G  GAPG
Sbjct: 1045 GIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPG 1104

Query: 260  DQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPG 319
              G  G PG+ GP GD G +G +G+ G PG +G  GLPG  G  G  G+ G +G  G PG
Sbjct: 1105 SPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPG 1164

Query: 320  PPGDAGLQGL----PGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPR 375
            P G+ G  GL    PG  G PGA+G  G++G+ G PG PG+ G  G  G +GP G  G  
Sbjct: 1165 PAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFP 1224

Query: 376  GPQGLPGS--RGELGPVGSPGLPGKLGSLGSPGLPGLPGPPG--LPGMKGDRGVVGEPGP 431
            GP GLPG+   G+ G  G P      GS GSPG PG PGPPG  + G+KGD+G +G PGP
Sbjct: 1225 GPPGLPGAIIPGQTGNRGPP------GSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGP 1278

Query: 432  KGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGP 491
            KG  G +G+ G  G  G  G  GLPGP+G  G  G PG++G +G+ G  G  GP GP GP
Sbjct: 1279 KGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGP 1338

Query: 492  RGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGR 551
            +G          PGV+G PG            +++I                    LPG 
Sbjct: 1339 KGP---------PGVRGDPG-----------TLKII-------------------SLPGS 1359

Query: 552  PGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGEKGERGPPGRGPNGLP 611
            PGPPG PG P         G++G PG  GPPG LG  GP+G  G+ G+ G P  GP G  
Sbjct: 1360 PGPPGTPGEP---------GMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTP--GPAGEK 1408

Query: 612  GAIGLPGDP 620
            G  G  G+P
Sbjct: 1409 GNKGSKGEP 1417



 Score =  335 bits (859), Expect = 8e-92
 Identities = 226/562 (40%), Positives = 269/562 (47%), Gaps = 82/562 (14%)

Query: 190 GAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEP 249
           GAKGE GE   +G  G  G  G+ G  G +G PG QG +G  G+ G  G KG RG+ G P
Sbjct: 43  GAKGEKGE---KGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLP 99

Query: 250 GPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMP 309
           G  G PG PG  G  GP G  G  G  G++G +G PGLPG  G  G+PG  G  G  G P
Sbjct: 100 GFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAP 159

Query: 310 G--------TKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSG 361
                     KG+PG PG PG    QGLPG PG PG  G  G  G  G PG  G  G  G
Sbjct: 160 AKEEDIELDAKGDPGLPGAPGP---QGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216

Query: 362 KPGQQ--GPPGEVGPRGPQGLPGSRGEL-----GPVGSPGLPGKLGSLGSPGLPGLPGPP 414
             G++  G  GE G +G  G PG  G +     GP     L G+ G  G+ G PG PGP 
Sbjct: 217 HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPS 276

Query: 415 GLPGMK--------GDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPG 466
           GLPG          GD G+ G+PG  G  G  G EG  G RG  G +G  G KG  G+ G
Sbjct: 277 GLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIG 336

Query: 467 EPGLRGPE---GSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGR-------APTD 516
            PG RGP     +    G EG  GPPGPRG +G QG +G PGV G PG        AP  
Sbjct: 337 PPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGW 396

Query: 517 QHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPG-------PPGENGFPGQ 569
             +K       +     M        +G+ GLPG PGPPGPPG       PPG++G PG 
Sbjct: 397 PGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGY 456

Query: 570 MGIRGLPG-----------------IKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLP 611
           +G  G+PG                 I GPPG  GL G  G  G  G +G  G +G  G P
Sbjct: 457 LGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSP 516

Query: 612 GAIGLPGDPG-PASYGRNGRDGERG----PPGVAGIPGVPGP------------PGPPGL 654
           G  GLPG PG P + G  G  GE+G    P G  G+PG PG             PG PG+
Sbjct: 517 GNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGV 576

Query: 655 PGFCEPASCTMQAGQRAFNKGP 676
            G   P      +G++  ++GP
Sbjct: 577 KGLPGPKGELALSGEKG-DQGP 597



 Score =  317 bits (812), Expect = 2e-86
 Identities = 210/533 (39%), Positives = 248/533 (46%), Gaps = 113/533 (21%)

Query: 236 DKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTG 295
           DKG+    G  GE G +G PG PG  GQ+G  G  G  G +G +G  G+PGL G KG  G
Sbjct: 35  DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRG 94

Query: 296 LPGVDGRDGIPGMPGTKGE---------PGKPGPPGDAGLQGLPGV---PGIPGAKGVAG 343
           + G+ G  G PG+PGT G          PG  G  G+ G  GLPG    PGIPGA G+ G
Sbjct: 95  ISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKG 154

Query: 344 EKG-----------STGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGS 392
           +KG           + G PG PG  G  G PG  G PG VGP GP G  G  G +GP G 
Sbjct: 155 QKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGP 214

Query: 393 PGLPGK--LGSLGSPGLPGLPGPPGLPGM-----------------KGDRGVVGEPGPKG 433
            G  G+  +G  G  G+ GL GPPG PG                  KGD+G +GEPGP G
Sbjct: 215 KGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274

Query: 434 EQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGV----------- 482
             G  G E    E+G  GD GL G  G  G PG PG  G +G+RG PG+           
Sbjct: 275 PSGLPG-ESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKG 333

Query: 483 ----------------------EGPRGPPGPRGVQGEQGATGLPGVQGPPGR-------A 513
                                 EG  GPPGPRG +G QG +G PGV G PG        A
Sbjct: 334 DIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGA 393

Query: 514 PTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPP-------GPPGENGF 566
           P    +K       +     M        +G+ GLPG PGPPGPP       GPPG++G 
Sbjct: 394 PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGL 453

Query: 567 PGQMGIRGLPG-----------------IKGPPGALGLRGPKGDLGEKGERGPPG-RGPN 608
           PG +G  G+PG                 I GPPG  GL G  G  G  G +G  G +G  
Sbjct: 454 PGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSP 513

Query: 609 GLPGAIGLPGDPG-PASYGRNGRDGERG----PPGVAGIPGVPGPPGPPGLPG 656
           G PG  GLPG PG P + G  G  GE+G    P G  G+PG PG  G PG  G
Sbjct: 514 GSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKG 566



 Score =  258 bits (658), Expect = 2e-68
 Identities = 182/459 (39%), Positives = 207/459 (45%), Gaps = 86/459 (18%)

Query: 270 AGPKGDRGA----EGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAG 325
           A P   +G     +G     G  G KG+ G PG       PG PG KG  G  G PG  G
Sbjct: 23  AAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGP------PGSPGQKGFTGPEGLPGPQG 76

Query: 326 LQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRG 385
            +G PG+PG+ G+KGV   +G +G PG       SG PG  G PG  GP G  G+PG  G
Sbjct: 77  PKGFPGLPGLTGSKGV---RGISGLPGF------SGSPGLPGTPGNTGPYGLVGVPGCSG 127

Query: 386 ELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPG--------MKGDRGVVGEPGPKGEQGA 437
             G  G PGLPG LG  G PG  GL G  G P          KGD G+ G PGP+G  G 
Sbjct: 128 SKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGP 187

Query: 438 SGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLR--GPEGSRGLPGVEGPRGPPGP---- 491
            G  G  G  G  G  G PG  G  G  G  G R  G +G RG+ G+ GP GPPG     
Sbjct: 188 PGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVT 247

Query: 492 ----------RGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRP 541
                     +G +G++GA G PG  GP G                + + +E  A     
Sbjct: 248 LTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPG-------------ESYGSEKGAP---G 291

Query: 542 DSGATGLPGR---PGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGP-------- 590
           D G  G PG+   PG PG  G  G  GFPG MG  G+ G KG  G  G RGP        
Sbjct: 292 DPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQ 351

Query: 591 -KGDLGEKGERGPPG-RGPNGLPGAIGLPGDPG---------PASYGRNGRDGERGPPG- 638
            KGD G  G  GP G RGP G  G  G+PG PG         P   G  G  GERG PG 
Sbjct: 352 EKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGK 411

Query: 639 -VAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGP 676
              G PG PG  G PGLPG   P       G   F KGP
Sbjct: 412 DAMGTPGSPGCAGSPGLPGSPGPPG---PPGDIVFRKGP 447



 Score =  185 bits (469), Expect = 1e-46
 Identities = 125/328 (38%), Positives = 145/328 (44%), Gaps = 55/328 (16%)

Query: 400 GSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPK 459
           G+ G  G  G PGPPG PG KG  G  G PGP+G +G  G  G  G +G  G  GLPG  
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 460 GSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHI 519
           GS G PG PG  GP G  G+PG  G +G  G  G+ G  G  G+PG  G  G+       
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 520 KQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRG----- 574
           + + +    +     A        G  G PG PGP GPPGPPG  GFPG MG RG     
Sbjct: 163 EDIELDAKGDPGLPGAPG----PQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHM 218

Query: 575 ------------LPGIKGPPGALG--------------LRGPKGDLGEKGERGPPGRGPN 608
                       + G+ GPPG  G              L+G KGD G  GE GPPG  P+
Sbjct: 219 GERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG--PS 276

Query: 609 GLPGAI-----GLPGDPG----------PASYGRNGRDGERGPPGVAGIPGVPGPP---G 650
           GLPG       G PGDPG          P   G  G  G RG PG+ G  G+ G     G
Sbjct: 277 GLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIG 336

Query: 651 PPGLPGFCEPASCTMQAGQRAFNKGPDP 678
           PPG  G  E      + G       P P
Sbjct: 337 PPGFRGPTEYYDTYQEKGDEGTPGPPGP 364



 Score =  173 bits (438), Expect = 5e-43
 Identities = 96/189 (50%), Positives = 103/189 (54%), Gaps = 15/189 (7%)

Query: 25   RGPPGEQGPPGPPGPPGVPG--IDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGAD 82
            RGPPG +G PG PGPPG PG  + GI GD+G  G PGP GP G  G  G PG+ G PG  
Sbjct: 1241 RGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTP 1300

Query: 83   GLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIP-GPPGPPGTAGLPGEL------GRV 135
            GL GP G PG  G  G KGE G PG  G  G   P GP GPPG  G PG L      G  
Sbjct: 1301 GLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSP 1360

Query: 136  GPVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEI 195
            GP G PG  G  G PGPPGP G +G     P  P    PG+ G PG PG  G KG KG  
Sbjct: 1361 GPPGTPGEPGMQGEPGPPGPPGNLG-----PCGPRG-KPGKDGKPGTPGPAGEKGNKGSK 1414

Query: 196  GEPGRQGHK 204
            GEP    H+
Sbjct: 1415 GEPESLFHQ 1423


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
            sapiens]
          Length = 1494

 Score =  513 bits (1320), Expect = e-145
 Identities = 313/752 (41%), Positives = 367/752 (48%), Gaps = 131/752 (17%)

Query: 26   GPPGEQGPPGPPGPPGV--PGIDGIDGDRGPKGPPGPPGPAGEPGK-------PGAPGKP 76
            G PG  GP GP GPPG    G  G+ G +G  G PGPPG AG  G+       PG PG P
Sbjct: 602  GSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPP 661

Query: 77   GTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVG 136
            G PG  G  GP G PGS+G  G  G PG  G  G PG G PGPPGP G  G PG  G +G
Sbjct: 662  GPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLG 721

Query: 137  PVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIG 196
              G  G  G PG PG PG +G           P    PG  G PG PG RG+ G  GEIG
Sbjct: 722  CPGKMGEPGLPGKPGLPGAKGE----------PAVAMPGGPGTPGFPGERGNSGEHGEIG 771

Query: 197  ---------EPGRQGHKGEEGDQGELGEVGAQGPPG--------AQGLRGITGIVGDKGE 239
                      PG +G  G  GD G+ G  G QGPPG        AQGL G+ G+ G +G 
Sbjct: 772  LPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGR 831

Query: 240  KGARGLDGEPGPQGL-----------PGAPGDQGQRGP---------PGEAGPKGDRGAE 279
            +G  G  G+PG  GL           PG PG QG+ GP         PG  GP G+ G  
Sbjct: 832  RGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVI 891

Query: 280  GARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLP--------- 330
            G  G PG  GP G  G PG  G+ G PG+PG KG+ G PG  G+ G +G P         
Sbjct: 892  GMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVI 951

Query: 331  ---GVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPP---GEVGPRGPQGLPGSR 384
               G PG+ G  G  GEKG+ G PG PG  G  G PG  GPP   G++G  G  G PG R
Sbjct: 952  GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLR 1011

Query: 385  ---GELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVG-----EPGPKGEQG 436
               G +G +G PG  GK G+LG PG  G PG PG+ G++GD+G  G      PGP G  G
Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071

Query: 437  ASGEEGEAGERGELGDIGLP------GPKGSAGNPGEP------------------GLRG 472
              G  G+ G++GE+G  G P      GP+G+ G+PG P                  GL G
Sbjct: 1072 DPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLG 1131

Query: 473  PEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPG-----RAPTDQHIKQVCMRVI 527
            P G RG PG+ G  G PGP G++G+QG  G+PG  G  G     RAP             
Sbjct: 1132 PPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAK 1191

Query: 528  QEHFA--------EMAASLKRPDSGATGLPGRPGPPGPPGP--PGENGFPGQMGIRGLPG 577
             +  A           A       G TG+ G PGPPG PG   PG+ G  G  G RG PG
Sbjct: 1192 GDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPG 1251

Query: 578  IKGPPG-----ALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPG-------PAS 624
              GPPG      +G++G KG +G  G +GPPG  G  G PG +G PG PG       P  
Sbjct: 1252 APGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGF 1311

Query: 625  YGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
             G  G  GE+G PG  G  G PGP GP G PG
Sbjct: 1312 QGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG 1343



 Score =  498 bits (1283), Expect = e-141
 Identities = 327/815 (40%), Positives = 378/815 (46%), Gaps = 207/815 (25%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGP-----------PGPPGPAGEPGKPGAPG 74
            GPPG  G PGP GPPG+PG  G  GD G  GP           PGPPGP G+ G PG  G
Sbjct: 659  GPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKG 718

Query: 75   KPGTPGADGLTGPDGSPGSIGSKGQKGE--PGVPGSRGFPGR----------GIPGPPGP 122
              G PG  G  G  G PG  G+KG+     PG PG+ GFPG           G+PG PG 
Sbjct: 719  SLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGL 778

Query: 123  PGTAGLPGELGRVGPVGDPGRRGPPGPPGPPG-----PRGTIGFHDGDPLCPNACPPGRS 177
            PGT   PG  G  GP GDPG+ GPPG  GPPG     PRG  G    + L       G++
Sbjct: 779  PGT---PGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKT 835

Query: 178  GYPGLPGMRG--HKGAKGEIGEPGRQGHKGEEGDQGELG---EVGAQGPPGAQGLRGITG 232
            G  G PG+ G    G  GE G PG  GH+GE G  G+ G     G  GPPG  G+ G+ G
Sbjct: 836  GPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMG 895

Query: 233  IVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGAR------GIPG 286
              G  G  G  G  G PG +G PG PG +GQRG PG  G +GD+G  G        G  G
Sbjct: 896  FPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKG 955

Query: 287  LPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGP---------------PGDAGLQGLPG 331
             PG KG  G PG  G  G+PGMPG KG  G PGP               PG+ GL+G+PG
Sbjct: 956  EPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPG 1015

Query: 332  V------------------------PGIPGAKGVAGEKGS--------------TGAPGK 353
                                     PG+PG  G+ G+KG               TG PG 
Sbjct: 1016 SMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGL 1075

Query: 354  PGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLG---------- 403
            PG MG  G+ GQ GPPG +GP GP+G PGS G  G  G PG  G LG  G          
Sbjct: 1076 PGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGI 1135

Query: 404  --SPGLPGLPGPPGLPGMKGDRGVVGEPGP-------------------------KGEQG 436
               PGLPG PG PG  G++GD+G  G PGP                         KG++G
Sbjct: 1136 RGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRG 1195

Query: 437  ASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGL-----------RGPEGSRGLPGVEGP 485
            A G  G  G +G +GD G  GP G  G PG PGL           RGP GSRG PG  GP
Sbjct: 1196 APGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGP 1255

Query: 486  RGPPGPR--GVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDS 543
             GPPG    G++G++G+ G PG +GPPG A                        +  P  
Sbjct: 1256 PGPPGSHVIGIKGDKGSMGHPGPKGPPGTA----------------------GDMGPP-- 1291

Query: 544  GATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKG---PPGALGLRGPKGDLGE---- 596
            G  G PG PG PGP G PG  GFPG  G +G PG  G   PPG +G +GP G  G+    
Sbjct: 1292 GRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTL 1351

Query: 597  --------------------KGERGPPGR-------GPNGLPGAIGLPGDPGPASYGRNG 629
                                +GE GPPG        GP G PG  G PG PGPA  G  G
Sbjct: 1352 KIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPA--GEKG 1409

Query: 630  RDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCT 664
              G +G PG AG  G+PG  G  G  G   PA+ T
Sbjct: 1410 NKGSKGEPGPAGSDGLPGLKGKRGDSG--SPATWT 1442



 Score =  489 bits (1259), Expect = e-138
 Identities = 325/771 (42%), Positives = 359/771 (46%), Gaps = 144/771 (18%)

Query: 7    DRGALGLLLLGLCLCAAQRGPPGEQGPPGPPGPP-------GVPGIDGIDGDRGPKGPPG 59
            +RG  G   +G        G PG  G PGPPGPP       G PG  G+ G  G  G PG
Sbjct: 405  ERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPG 464

Query: 60   PPGPAGEPGK-----PGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG- 113
              GP GEPG      P  PG PG PG  GL G  G PG  G+ G KG PG PG+ G PG 
Sbjct: 465  VDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGF 524

Query: 114  RGIPGPPGPPGTAGLPGEL----GRVGPVGDPGRRGPPGP------PGPPGPRGTIGFHD 163
             G PG  G PG  G  GE     G+VG  GDPG RG PG       PG PG +G  G   
Sbjct: 525  PGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKG 584

Query: 164  GDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPG 223
               L   +   G  G PG PG  G  G  G  G PG  G +GE G QG  G  GA GPPG
Sbjct: 585  ELAL---SGEKGDQGPPGDPGSPGSPGPAGPAGPPG-YGPQGEPGLQGTQGVPGAPGPPG 640

Query: 224  AQGLRGITGI-VGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGAR 282
              G RG   +     G  G  G  G PGPQG PG PG  G+ G PG  GP G+ G  G  
Sbjct: 641  EAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI- 699

Query: 283  GIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAG-----LQGLPGVPGIPG 337
            G PG PGPKGD G PG  G  G PG  G  G PGKPG PG  G     + G PG PG PG
Sbjct: 700  GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759

Query: 338  AKGVAGEKGSTGAPGKPGQMGNSGK---------PGQQGPPGE--------VGPRGPQGL 380
             +G +GE G  G PG PG  G  G          PGQ GPPGE         GPRG QGL
Sbjct: 760  ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819

Query: 381  P---------GSRGELGPVGSPGLP-----------------------GKLGSLGSPGLP 408
            P         G RG+ GP G PG+P                       G LG  G PG P
Sbjct: 820  PGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNP 879

Query: 409  GL---------------------PGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGER 447
            G+                     PGPPG PG  G RG  G PG KG++G  G +GE G++
Sbjct: 880  GILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDK 939

Query: 448  GE---------LGDIGLPGPKGSAGNPGEPGLRGPEGS---RGLPGVEGPRGPPGPRGVQ 495
            G          +GD G PG KG AGNPGE G RG  G    +GL G+ GP GPPGPRG  
Sbjct: 940  GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL 999

Query: 496  GEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPP 555
            G  G  G PG++G PG                      M     +   G  G PGR G P
Sbjct: 1000 GSTGNPGEPGLRGIPG------------------SMGNMGMPGSKGKRGTLGFPGRAGRP 1041

Query: 556  GPPGPPGENGFPGQMGIR--GLPGIKGPPGALGLRGPKGDLGEKGERGPPG-------RG 606
            G PG  G  G  G+ G      PG  GP G  GL G  G  GE G+ GPPG        G
Sbjct: 1042 GLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEG 1101

Query: 607  PNGLPGAIGLPGDPGP-ASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
              G PG+ GLPG PGP    G  G  G  GPPG+ G PG+PG PG PG  G
Sbjct: 1102 APGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMG 1152



 Score =  488 bits (1256), Expect = e-138
 Identities = 303/687 (44%), Positives = 340/687 (49%), Gaps = 107/687 (15%)

Query: 24   QRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPG--APGKPGTPGA 81
            +RG  GE G  G PG PG+PG  G +G  GP+G PG PGP GE G PG    G  G  G 
Sbjct: 760  ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819

Query: 82   DGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDP 141
             GL G  G  G  G  G KG+PG+P   G    G PG  G PG  G  GE+G +G  G P
Sbjct: 820  PGLNGLKGQQGRRGKTGPKGDPGIP---GLDRSGFPGETGSPGIPGHQGEMGPLGQRGYP 876

Query: 142  GRRGPPGPPGPPGPRGTIGFHDGDPLCPNAC-PPGRSGYPGLPGMRGHKGAKGEIGEPGR 200
            G  G  GPPG  G  G +GF       P A  PPG  G PG PG RG  G  G  G+ G 
Sbjct: 877  GNPGILGPPGEDGVIGMMGF-------PGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGT 929

Query: 201  QGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGD 260
             G KGE+GD+G  G        G +G  G+ G  G+ GEKG RG+ G PG +GL G PG 
Sbjct: 930  PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989

Query: 261  QGQRGPPGEAGPKGDRGAEGARGIP------GLPGPKGDTGLPGVDGRDGIPGMP----- 309
             G  GP G+ G  G+ G  G RGIP      G+PG KG  G  G  GR G PG+P     
Sbjct: 990  AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL 1049

Query: 310  -GTKGEPG-----KPGPPGDAGLQGLP------GVPGIPGAKGVAGEKGSTGAPGKPGQM 357
             G KGEPG     +PGPPG  G  GLP      G  G PG  G  G  G  GAPG PG  
Sbjct: 1050 QGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSP 1109

Query: 358  GNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGP---- 413
            G  GKPG  G  G  G +G  G PG RG  G  G PG PG +G  G  G  G+PGP    
Sbjct: 1110 GLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEK 1169

Query: 414  ---------------PGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGP 458
                           PG  G KGDRG  G PG  G +GA    G+AG RG  G  G PGP
Sbjct: 1170 GETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAM---GDAGPRGPTGIEGFPGP 1226

Query: 459  KGSAGN--PGEPGLRGPEGSRGLPGVEGPRGPPGPR--GVQGEQGATGLPGVQGPPGRAP 514
             G  G   PG+ G RGP GSRG PG  GP GPPG    G++G++G+ G PG +GPPG A 
Sbjct: 1227 PGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTA- 1285

Query: 515  TDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRG 574
                                         G  G PGR G PG PG PG  G PG  G  G
Sbjct: 1286 -----------------------------GDMGPPGRLGAPGTPGLPGPRGDPGFQGFPG 1316

Query: 575  LPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGPASYGRNGRDGE 633
            + G KG PG LG  GP G +G K   GPPG RG  G    I LPG PGP           
Sbjct: 1317 VKGEKGNPGFLGSIGPPGPIGPK---GPPGVRGDPGTLKIISLPGSPGPP---------- 1363

Query: 634  RGPPGVAGIPGVPGPPGPPGLPGFCEP 660
             G PG  G+ G PGPPGPPG  G C P
Sbjct: 1364 -GTPGEPGMQGEPGPPGPPGNLGPCGP 1389



 Score =  484 bits (1245), Expect = e-136
 Identities = 308/736 (41%), Positives = 372/736 (50%), Gaps = 127/736 (17%)

Query: 17  GLCLCAAQRGPPGEQGPPGPPGPPGVPGI---DGIDGDRGPKGPPGPPGPAGE------- 66
           G C C   +G  GE+G PGPPG PG  G    +G+ G +GPKG PG PG  G        
Sbjct: 37  GQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGIS 96

Query: 67  --PGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----------- 113
             PG  G+PG PGTPG  G  G  G PG  GSKG++G PG+PG+ G+PG           
Sbjct: 97  GLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQK 156

Query: 114 -------------RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIG 160
                        +G PG PG PG  GLPG  G  GPVG PG  G  G PG  GPRG  G
Sbjct: 157 GAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216

Query: 161 FHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEI-----GEPGRQGHKGEEGDQGELGE 215
            H G+ +       G  G  G+ G+ G  G  G +     G   R   KGE+GD+G +GE
Sbjct: 217 -HMGERVI------GHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGE 269

Query: 216 VGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQ---GQRGPPGEAGP 272
               GPPG  GL G      +KG  G  GL G+PG  G+PG PG +   G RG PG  G 
Sbjct: 270 ---PGPPGPSGLPG-ESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGE 325

Query: 273 KGDRGAEGARGIPGLPGP---------KGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGD 323
            G +G +G  G PG  GP         KGD G PG  G  G  G  G  G PG PG PG 
Sbjct: 326 DGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGS 385

Query: 324 A--GLQGLPGVPGIPGAKGVAGEKG--STGAPGKPGQMGNSGKPGQQGPPGEVGP----R 375
           +  GL+G PG PG+ G+KG  G  G  + G PG PG  G+ G PG  GPPG  G     +
Sbjct: 386 SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRK 445

Query: 376 GPQGLPGSRGELGPVGSPGLPGKLGSLGSPGL-----PGLPGPPGLPGMKGDRGVVGEPG 430
           GP   PG  G  G +GSPG+PG  G  G PGL     P +PGPPGLPG+ G  GV G P 
Sbjct: 446 GP---PGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIP- 501

Query: 431 PKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRG----PEGSRGLPGVEGPR 486
             G QGA+G +G  G  G  G  G PG  G+ G+PG  G +G    PEG  G+PG  G R
Sbjct: 502 --GRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLR 559

Query: 487 GPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGAT 546
           G PG +G+ G  G  G+ G+ GP G                     E+A S ++ D G  
Sbjct: 560 GQPGRKGLDGIPGTPGVKGLPGPKG---------------------ELALSGEKGDQGPP 598

Query: 547 GLPGRPGPPGPPGPPGENGF--PGQMGIRGLPGIKGPPGALGLRGPKGDL-------GEK 597
           G PG PG PGP GP G  G+   G+ G++G  G+ G PG  G  GP+G+L       G  
Sbjct: 599 GDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPP 658

Query: 598 GERGPPG----RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPG 653
           G  GPPG    +GP G+PG++G  GDP     G  G DGE G PG+ G PG PGP G  G
Sbjct: 659 GPPGPPGHPGPQGPPGIPGSLGKCGDP-----GLPGPDGEPGIPGI-GFPGPPGPKGDQG 712

Query: 654 LPGFCEPASCTMQAGQ 669
            PG      C  + G+
Sbjct: 713 FPGTKGSLGCPGKMGE 728



 Score =  476 bits (1225), Expect = e-134
 Identities = 310/765 (40%), Positives = 374/765 (48%), Gaps = 144/765 (18%)

Query: 15  LLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRG-----------PKGPPGPPGP 63
           L+G+  C+  +G  G  G PG  G PG+PG  G+ G +G            KG PG PG 
Sbjct: 119 LVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGA 178

Query: 64  AGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPG--VPGSRGFPG-RGIPGPP 120
            G  G PG PG PG  G  G  G  G PG++G +G KG  G  V G +G  G +G+ GPP
Sbjct: 179 PGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPP 238

Query: 121 GPPGT-----------AGLPGELGRVGPVGDPGRRGP-----------PGPPGPPGPRGT 158
           GPPGT             L GE G  G +G+PG  GP            G PG PG +G 
Sbjct: 239 GPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGK 298

Query: 159 IGFHDGDPLCPNA-CPPGRSGYPGLPGMRGHKGAKGEIGEPGRQG---------HKGEEG 208
            G  DG P  P +    G  G+PGL G  G KG KG+IG PG +G          KG+EG
Sbjct: 299 PG-KDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEG 357

Query: 209 DQGELGEVGAQGP-----------------PGAQGLRGITGIVGDKGEKG-----ARGLD 246
             G  G  GA+GP                 PG +G  G  G+ G KGE+G     A G  
Sbjct: 358 TPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTP 417

Query: 247 GEPGPQGLPGAPGDQGQRGPPGE----AGPKGDRGAE---GARGIPGLPGPKGDTGL--- 296
           G PG  G PG PG  G  GPPG+     GP GD G     G+ GIPG+ GPKG+ GL   
Sbjct: 418 GSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCT 477

Query: 297 -----PGVDGRDGIPGMPGTKGEPGK---------PGPPGDAGLQGLPGVPGIPGAKGVA 342
                PG  G  G+PG+ G KG PG+         PG PG+ GL G PG PG  G  G+ 
Sbjct: 478 QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK 537

Query: 343 GEKGST-------GAPGKPGQMGNSGKPGQQGPPGE------VGPRGPQGLPGSRGELGP 389
           GEKG T       G PG PG  G  G+ G  G PG        GP+G   L G +G+ GP
Sbjct: 538 GEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGP 597

Query: 390 VGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGE--------- 440
            G PG PG  G  G  G PG  GP G PG++G +GV G PGP GE G  GE         
Sbjct: 598 PGDPGSPGSPGPAGPAGPPGY-GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPG 656

Query: 441 -EGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGV--EGPRGPPGPRGVQGE 497
             G  G  G  G  G PG  GS G  G+PGL GP+G  G+PG+   GP GP G +G  G 
Sbjct: 657 PPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGT 716

Query: 498 QGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGP 557
           +G+ G PG  G PG                      +  +   P   A  +PG PG PG 
Sbjct: 717 KGSLGCPGKMGEPGLPGK----------------PGLPGAKGEP---AVAMPGGPGTPGF 757

Query: 558 PGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGE---KGERGPPGRGPNGLPGAI 614
           PG  G +G  G++G+ GLPG+ G PG  GL GP+GD G+    GE+GPPGR   G  GA 
Sbjct: 758 PGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQ 817

Query: 615 GLPGDPG-PASYGRNGRDGERGPPGVAGI--PGVPGPPGPPGLPG 656
           GLPG  G     GR G+ G +G PG+ G+   G PG  G PG+PG
Sbjct: 818 GLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPG 862



 Score =  463 bits (1192), Expect = e-130
 Identities = 293/695 (42%), Positives = 343/695 (49%), Gaps = 134/695 (19%)

Query: 24   QRGPPGEQGPPG-----PPGPPGVPGIDGIDGDRG------PKGPPGPPG---------- 62
            Q GPPGEQGPPG     P G  G+PG++G+ G +G      PKG PG PG          
Sbjct: 796  QPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGET 855

Query: 63   -------------PAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSR 109
                         P G+ G PG PG  G PG DG+ G  G PG+IG  G  G PG PG R
Sbjct: 856  GSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQR 915

Query: 110  GFPG-------------------RGIPGP------------PGPPGTAGLPGELGRVGPV 138
            G PG                   +G PGP            PG  G AG PGE G  G  
Sbjct: 916  GSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVP 975

Query: 139  GDPGRRGP---PGPPGPPGPRGTIGFHDGDPLCPNACP-PGRSGYPGLPGMRGHKGAKGE 194
            G PG +G    PGP GPPGPRG +G   G+P  P     PG  G  G+PG +G +G  G 
Sbjct: 976  GMPGLKGLKGLPGPAGPPGPRGDLG-STGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGF 1034

Query: 195  IGEPGRQGHKGEEGDQGELGEVGAQ-----GPPGAQGLRGITGIVGDKGEKGARGLDGEP 249
             G  GR G  G  G QG+ GE G       GPPG  G  G+ G +G KGE G  G  G  
Sbjct: 1035 PGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHL 1094

Query: 250  GPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMP 309
            GP G  GAPG  G  G PG+ GP GD G +G +G+ G PG +G  GLPG  G  G  G+ 
Sbjct: 1095 GPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIR 1154

Query: 310  GTKGEPGKPGPPGDAGLQGL----PGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQ 365
            G +G  G PGP G+ G  GL    PG  G PGA+G  G++G+ G PG PG+ G  G  G 
Sbjct: 1155 GDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGP 1214

Query: 366  QGPPGEVGPRGPQGLPGS--RGELGPVGSPGLPGKLGSLGSPGLPGLPGPPG--LPGMKG 421
            +GP G  G  GP GLPG+   G+ G  G PG      S GSPG PG PGPPG  + G+KG
Sbjct: 1215 RGPTGIEGFPGPPGLPGAIIPGQTGNRGPPG------SRGSPGAPGPPGPPGSHVIGIKG 1268

Query: 422  DRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGL-- 479
            D+G +G PGPKG  G +G+ G  G  G  G  GLPGP+G  G  G PG++G +G+ G   
Sbjct: 1269 DKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLG 1328

Query: 480  ----PGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMA 535
                PG  GP+GPPG RG  G      LPG  GPPG                        
Sbjct: 1329 SIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGT----------------------- 1365

Query: 536  ASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLG 595
                         PG PG  G PGPPG  G  G  G RG PG  G PG  G  G KG+ G
Sbjct: 1366 -------------PGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKG 1412

Query: 596  EKGERGPPGRGPNGLPGAIGLPGDPG-PASYGRNG 629
             KGE GP   G +GLPG  G  GD G PA++   G
Sbjct: 1413 SKGEPGP--AGSDGLPGLKGKRGDSGSPATWTTRG 1445



 Score =  337 bits (865), Expect = 2e-92
 Identities = 202/486 (41%), Positives = 237/486 (48%), Gaps = 87/486 (17%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 85
            G PGE+G  G PG PG+ G+ G+ G  GP GP G  G  G PG+PG  G PG+ G  G+ 
Sbjct: 964  GNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMP 1023

Query: 86   GPDGSPGSIGSKGQKGEPGVPGSRGFPG--------RGI-PGPPGPPGTAGLPGELGR-- 134
            G  G  G++G  G+ G PG+PG  G  G         G  PGPPGP G  GLPG++G+  
Sbjct: 1024 GSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKG 1083

Query: 135  -------------VGPVGDPGRRGPPGPPGPPGPRGTIGFHD-----GDPLCPNACPPGR 176
                          GP G PG  G PG PG PGP G +GF       G P      PPG 
Sbjct: 1084 EMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRG--PPGL 1141

Query: 177  SGYPGLPGMRGHKGAKGEIGEPGRQGHKGE----------EGDQGELGEVGAQGPPGAQG 226
             G+PG PG  G +G +G  G PG  G KGE           G+ G  G  G +G PG  G
Sbjct: 1142 PGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPG 1201

Query: 227  LRGITGIVGDKGEKGARGLDGEPGPQGLPGA--PGDQGQRGPPGEAGP------------ 272
            L G  G +GD G +G  G++G PGP GLPGA  PG  G RGPPG  G             
Sbjct: 1202 LPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGS 1261

Query: 273  -----KGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPG----------- 316
                 KGD+G+ G  G  G PG  GD G PG  G  G PG+PG +G+PG           
Sbjct: 1262 HVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEK 1321

Query: 317  -------KPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPP 369
                     GPPG  G +G PGV G PG   +    GS G PG PG+ G  G+PG  GPP
Sbjct: 1322 GNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPP 1381

Query: 370  GEVGPRGPQGLPGS---------RGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMK 420
            G +GP GP+G PG           GE G  GS G PG  GS G PGL G  G  G P   
Sbjct: 1382 GNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATW 1441

Query: 421  GDRGVV 426
              RG V
Sbjct: 1442 TTRGFV 1447



 Score =  335 bits (859), Expect = 8e-92
 Identities = 226/562 (40%), Positives = 269/562 (47%), Gaps = 82/562 (14%)

Query: 190 GAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEP 249
           GAKGE GE   +G  G  G  G+ G  G +G PG QG +G  G+ G  G KG RG+ G P
Sbjct: 43  GAKGEKGE---KGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLP 99

Query: 250 GPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMP 309
           G  G PG PG  G  GP G  G  G  G++G +G PGLPG  G  G+PG  G  G  G P
Sbjct: 100 GFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAP 159

Query: 310 G--------TKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSG 361
                     KG+PG PG PG    QGLPG PG PG  G  G  G  G PG  G  G  G
Sbjct: 160 AKEEDIELDAKGDPGLPGAPGP---QGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216

Query: 362 KPGQQ--GPPGEVGPRGPQGLPGSRGEL-----GPVGSPGLPGKLGSLGSPGLPGLPGPP 414
             G++  G  GE G +G  G PG  G +     GP     L G+ G  G+ G PG PGP 
Sbjct: 217 HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPS 276

Query: 415 GLPGMK--------GDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPG 466
           GLPG          GD G+ G+PG  G  G  G EG  G RG  G +G  G KG  G+ G
Sbjct: 277 GLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIG 336

Query: 467 EPGLRGPE---GSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGR-------APTD 516
            PG RGP     +    G EG  GPPGPRG +G QG +G PGV G PG        AP  
Sbjct: 337 PPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGW 396

Query: 517 QHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPG-------PPGENGFPGQ 569
             +K       +     M        +G+ GLPG PGPPGPPG       PPG++G PG 
Sbjct: 397 PGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGY 456

Query: 570 MGIRGLPG-----------------IKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLP 611
           +G  G+PG                 I GPPG  GL G  G  G  G +G  G +G  G P
Sbjct: 457 LGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSP 516

Query: 612 GAIGLPGDPG-PASYGRNGRDGERG----PPGVAGIPGVPGP------------PGPPGL 654
           G  GLPG PG P + G  G  GE+G    P G  G+PG PG             PG PG+
Sbjct: 517 GNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGV 576

Query: 655 PGFCEPASCTMQAGQRAFNKGP 676
            G   P      +G++  ++GP
Sbjct: 577 KGLPGPKGELALSGEKG-DQGP 597



 Score =  317 bits (812), Expect = 2e-86
 Identities = 210/533 (39%), Positives = 248/533 (46%), Gaps = 113/533 (21%)

Query: 236 DKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTG 295
           DKG+    G  GE G +G PG PG  GQ+G  G  G  G +G +G  G+PGL G KG  G
Sbjct: 35  DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRG 94

Query: 296 LPGVDGRDGIPGMPGTKGE---------PGKPGPPGDAGLQGLPGV---PGIPGAKGVAG 343
           + G+ G  G PG+PGT G          PG  G  G+ G  GLPG    PGIPGA G+ G
Sbjct: 95  ISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKG 154

Query: 344 EKG-----------STGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGS 392
           +KG           + G PG PG  G  G PG  G PG VGP GP G  G  G +GP G 
Sbjct: 155 QKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGP 214

Query: 393 PGLPGK--LGSLGSPGLPGLPGPPGLPGM-----------------KGDRGVVGEPGPKG 433
            G  G+  +G  G  G+ GL GPPG PG                  KGD+G +GEPGP G
Sbjct: 215 KGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274

Query: 434 EQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGV----------- 482
             G  G E    E+G  GD GL G  G  G PG PG  G +G+RG PG+           
Sbjct: 275 PSGLPG-ESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKG 333

Query: 483 ----------------------EGPRGPPGPRGVQGEQGATGLPGVQGPPGR-------A 513
                                 EG  GPPGPRG +G QG +G PGV G PG        A
Sbjct: 334 DIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGA 393

Query: 514 PTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPP-------GPPGENGF 566
           P    +K       +     M        +G+ GLPG PGPPGPP       GPPG++G 
Sbjct: 394 PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGL 453

Query: 567 PGQMGIRGLPG-----------------IKGPPGALGLRGPKGDLGEKGERGPPG-RGPN 608
           PG +G  G+PG                 I GPPG  GL G  G  G  G +G  G +G  
Sbjct: 454 PGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSP 513

Query: 609 GLPGAIGLPGDPG-PASYGRNGRDGERG----PPGVAGIPGVPGPPGPPGLPG 656
           G PG  GLPG PG P + G  G  GE+G    P G  G+PG PG  G PG  G
Sbjct: 514 GSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKG 566



 Score =  258 bits (658), Expect = 2e-68
 Identities = 182/459 (39%), Positives = 207/459 (45%), Gaps = 86/459 (18%)

Query: 270 AGPKGDRGA----EGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAG 325
           A P   +G     +G     G  G KG+ G PG       PG PG KG  G  G PG  G
Sbjct: 23  AAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGP------PGSPGQKGFTGPEGLPGPQG 76

Query: 326 LQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRG 385
            +G PG+PG+ G+KGV   +G +G PG       SG PG  G PG  GP G  G+PG  G
Sbjct: 77  PKGFPGLPGLTGSKGV---RGISGLPGF------SGSPGLPGTPGNTGPYGLVGVPGCSG 127

Query: 386 ELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPG--------MKGDRGVVGEPGPKGEQGA 437
             G  G PGLPG LG  G PG  GL G  G P          KGD G+ G PGP+G  G 
Sbjct: 128 SKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGP 187

Query: 438 SGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLR--GPEGSRGLPGVEGPRGPPGP---- 491
            G  G  G  G  G  G PG  G  G  G  G R  G +G RG+ G+ GP GPPG     
Sbjct: 188 PGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVT 247

Query: 492 ----------RGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRP 541
                     +G +G++GA G PG  GP G                + + +E  A     
Sbjct: 248 LTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPG-------------ESYGSEKGAP---G 291

Query: 542 DSGATGLPGR---PGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGP-------- 590
           D G  G PG+   PG PG  G  G  GFPG MG  G+ G KG  G  G RGP        
Sbjct: 292 DPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQ 351

Query: 591 -KGDLGEKGERGPPG-RGPNGLPGAIGLPGDPG---------PASYGRNGRDGERGPPG- 638
            KGD G  G  GP G RGP G  G  G+PG PG         P   G  G  GERG PG 
Sbjct: 352 EKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGK 411

Query: 639 -VAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGP 676
              G PG PG  G PGLPG   P       G   F KGP
Sbjct: 412 DAMGTPGSPGCAGSPGLPGSPGPPG---PPGDIVFRKGP 447



 Score =  185 bits (469), Expect = 1e-46
 Identities = 125/328 (38%), Positives = 145/328 (44%), Gaps = 55/328 (16%)

Query: 400 GSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPK 459
           G+ G  G  G PGPPG PG KG  G  G PGP+G +G  G  G  G +G  G  GLPG  
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 460 GSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHI 519
           GS G PG PG  GP G  G+PG  G +G  G  G+ G  G  G+PG  G  G+       
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 520 KQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRG----- 574
           + + +    +     A        G  G PG PGP GPPGPPG  GFPG MG RG     
Sbjct: 163 EDIELDAKGDPGLPGAPG----PQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHM 218

Query: 575 ------------LPGIKGPPGALG--------------LRGPKGDLGEKGERGPPGRGPN 608
                       + G+ GPPG  G              L+G KGD G  GE GPPG  P+
Sbjct: 219 GERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG--PS 276

Query: 609 GLPGAI-----GLPGDPG----------PASYGRNGRDGERGPPGVAGIPGVPGPP---G 650
           GLPG       G PGDPG          P   G  G  G RG PG+ G  G+ G     G
Sbjct: 277 GLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIG 336

Query: 651 PPGLPGFCEPASCTMQAGQRAFNKGPDP 678
           PPG  G  E      + G       P P
Sbjct: 337 PPGFRGPTEYYDTYQEKGDEGTPGPPGP 364



 Score =  125 bits (313), Expect = 2e-28
 Identities = 87/246 (35%), Positives = 101/246 (41%), Gaps = 77/246 (31%)

Query: 25   RGPPGEQGPPGPPGPPGVPG--IDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGAD 82
            RGPPG +G PG PGPPG PG  + GI GD+G  G PGP GP G  G  G PG+ G PG  
Sbjct: 1241 RGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTP 1300

Query: 83   GLTGPDGSPGSIGS---KGQKGEPGV---------------PGSRGFPGR----GIPGPP 120
            GL GP G PG  G    KG+KG PG                PG RG PG      +PG P
Sbjct: 1301 GLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSP 1360

Query: 121  GPPGTAGLPGELGRVGPVGDPG-------------------------------------- 142
            GPPGT G PG  G  GP G PG                                      
Sbjct: 1361 GPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPA 1420

Query: 143  ----------RRGPPGPPGPPGPRGTIGFHDGD----PLCPNACPPGRSGYPGLPGMRGH 188
                      +RG  G P     RG +          P CP    P  SG+  L  ++G+
Sbjct: 1421 GSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEGTVPLYSGFSFL-FVQGN 1479

Query: 189  KGAKGE 194
            + A G+
Sbjct: 1480 QRAHGQ 1485



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 26/66 (39%), Positives = 31/66 (46%), Gaps = 12/66 (18%)

Query: 16   LGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGK 75
            LG C    + G  G+ G PGP             G++G KG  G PGPAG  G PG  GK
Sbjct: 1384 LGPCGPRGKPGKDGKPGTPGPA------------GEKGNKGSKGEPGPAGSDGLPGLKGK 1431

Query: 76   PGTPGA 81
             G  G+
Sbjct: 1432 RGDSGS 1437


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
            sapiens]
          Length = 1637

 Score =  513 bits (1320), Expect = e-145
 Identities = 313/752 (41%), Positives = 367/752 (48%), Gaps = 131/752 (17%)

Query: 26   GPPGEQGPPGPPGPPGV--PGIDGIDGDRGPKGPPGPPGPAGEPGK-------PGAPGKP 76
            G PG  GP GP GPPG    G  G+ G +G  G PGPPG AG  G+       PG PG P
Sbjct: 602  GSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPP 661

Query: 77   GTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVG 136
            G PG  G  GP G PGS+G  G  G PG  G  G PG G PGPPGP G  G PG  G +G
Sbjct: 662  GPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLG 721

Query: 137  PVGDPGRRGPPGPPGPPGPRGTIGFHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIG 196
              G  G  G PG PG PG +G           P    PG  G PG PG RG+ G  GEIG
Sbjct: 722  CPGKMGEPGLPGKPGLPGAKGE----------PAVAMPGGPGTPGFPGERGNSGEHGEIG 771

Query: 197  ---------EPGRQGHKGEEGDQGELGEVGAQGPPG--------AQGLRGITGIVGDKGE 239
                      PG +G  G  GD G+ G  G QGPPG        AQGL G+ G+ G +G 
Sbjct: 772  LPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGR 831

Query: 240  KGARGLDGEPGPQGL-----------PGAPGDQGQRGP---------PGEAGPKGDRGAE 279
            +G  G  G+PG  GL           PG PG QG+ GP         PG  GP G+ G  
Sbjct: 832  RGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVI 891

Query: 280  GARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAGLQGLP--------- 330
            G  G PG  GP G  G PG  G+ G PG+PG KG+ G PG  G+ G +G P         
Sbjct: 892  GMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVI 951

Query: 331  ---GVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPP---GEVGPRGPQGLPGSR 384
               G PG+ G  G  GEKG+ G PG PG  G  G PG  GPP   G++G  G  G PG R
Sbjct: 952  GDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLR 1011

Query: 385  ---GELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVG-----EPGPKGEQG 436
               G +G +G PG  GK G+LG PG  G PG PG+ G++GD+G  G      PGP G  G
Sbjct: 1012 GIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTG 1071

Query: 437  ASGEEGEAGERGELGDIGLP------GPKGSAGNPGEP------------------GLRG 472
              G  G+ G++GE+G  G P      GP+G+ G+PG P                  GL G
Sbjct: 1072 DPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLG 1131

Query: 473  PEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPG-----RAPTDQHIKQVCMRVI 527
            P G RG PG+ G  G PGP G++G+QG  G+PG  G  G     RAP             
Sbjct: 1132 PPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAK 1191

Query: 528  QEHFA--------EMAASLKRPDSGATGLPGRPGPPGPPGP--PGENGFPGQMGIRGLPG 577
             +  A           A       G TG+ G PGPPG PG   PG+ G  G  G RG PG
Sbjct: 1192 GDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPG 1251

Query: 578  IKGPPG-----ALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPG-------PAS 624
              GPPG      +G++G KG +G  G +GPPG  G  G PG +G PG PG       P  
Sbjct: 1252 APGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGF 1311

Query: 625  YGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
             G  G  GE+G PG  G  G PGP GP G PG
Sbjct: 1312 QGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG 1343



 Score =  498 bits (1283), Expect = e-141
 Identities = 327/815 (40%), Positives = 378/815 (46%), Gaps = 207/815 (25%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGP-----------PGPPGPAGEPGKPGAPG 74
            GPPG  G PGP GPPG+PG  G  GD G  GP           PGPPGP G+ G PG  G
Sbjct: 659  GPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKG 718

Query: 75   KPGTPGADGLTGPDGSPGSIGSKGQKGE--PGVPGSRGFPGR----------GIPGPPGP 122
              G PG  G  G  G PG  G+KG+     PG PG+ GFPG           G+PG PG 
Sbjct: 719  SLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGL 778

Query: 123  PGTAGLPGELGRVGPVGDPGRRGPPGPPGPPG-----PRGTIGFHDGDPLCPNACPPGRS 177
            PGT   PG  G  GP GDPG+ GPPG  GPPG     PRG  G    + L       G++
Sbjct: 779  PGT---PGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKT 835

Query: 178  GYPGLPGMRG--HKGAKGEIGEPGRQGHKGEEGDQGELG---EVGAQGPPGAQGLRGITG 232
            G  G PG+ G    G  GE G PG  GH+GE G  G+ G     G  GPPG  G+ G+ G
Sbjct: 836  GPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMG 895

Query: 233  IVGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGAR------GIPG 286
              G  G  G  G  G PG +G PG PG +GQRG PG  G +GD+G  G        G  G
Sbjct: 896  FPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKG 955

Query: 287  LPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGP---------------PGDAGLQGLPG 331
             PG KG  G PG  G  G+PGMPG KG  G PGP               PG+ GL+G+PG
Sbjct: 956  EPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPG 1015

Query: 332  V------------------------PGIPGAKGVAGEKGS--------------TGAPGK 353
                                     PG+PG  G+ G+KG               TG PG 
Sbjct: 1016 SMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGL 1075

Query: 354  PGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLG---------- 403
            PG MG  G+ GQ GPPG +GP GP+G PGS G  G  G PG  G LG  G          
Sbjct: 1076 PGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGI 1135

Query: 404  --SPGLPGLPGPPGLPGMKGDRGVVGEPGP-------------------------KGEQG 436
               PGLPG PG PG  G++GD+G  G PGP                         KG++G
Sbjct: 1136 RGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRG 1195

Query: 437  ASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGL-----------RGPEGSRGLPGVEGP 485
            A G  G  G +G +GD G  GP G  G PG PGL           RGP GSRG PG  GP
Sbjct: 1196 APGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGP 1255

Query: 486  RGPPGPR--GVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDS 543
             GPPG    G++G++G+ G PG +GPPG A                        +  P  
Sbjct: 1256 PGPPGSHVIGIKGDKGSMGHPGPKGPPGTA----------------------GDMGPP-- 1291

Query: 544  GATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKG---PPGALGLRGPKGDLGE---- 596
            G  G PG PG PGP G PG  GFPG  G +G PG  G   PPG +G +GP G  G+    
Sbjct: 1292 GRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTL 1351

Query: 597  --------------------KGERGPPGR-------GPNGLPGAIGLPGDPGPASYGRNG 629
                                +GE GPPG        GP G PG  G PG PGPA  G  G
Sbjct: 1352 KIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPA--GEKG 1409

Query: 630  RDGERGPPGVAGIPGVPGPPGPPGLPGFCEPASCT 664
              G +G PG AG  G+PG  G  G  G   PA+ T
Sbjct: 1410 NKGSKGEPGPAGSDGLPGLKGKRGDSG--SPATWT 1442



 Score =  489 bits (1259), Expect = e-138
 Identities = 325/771 (42%), Positives = 359/771 (46%), Gaps = 144/771 (18%)

Query: 7    DRGALGLLLLGLCLCAAQRGPPGEQGPPGPPGPP-------GVPGIDGIDGDRGPKGPPG 59
            +RG  G   +G        G PG  G PGPPGPP       G PG  G+ G  G  G PG
Sbjct: 405  ERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPG 464

Query: 60   PPGPAGEPGK-----PGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG- 113
              GP GEPG      P  PG PG PG  GL G  G PG  G+ G KG PG PG+ G PG 
Sbjct: 465  VDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGF 524

Query: 114  RGIPGPPGPPGTAGLPGEL----GRVGPVGDPGRRGPPGP------PGPPGPRGTIGFHD 163
             G PG  G PG  G  GE     G+VG  GDPG RG PG       PG PG +G  G   
Sbjct: 525  PGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKG 584

Query: 164  GDPLCPNACPPGRSGYPGLPGMRGHKGAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPG 223
               L   +   G  G PG PG  G  G  G  G PG  G +GE G QG  G  GA GPPG
Sbjct: 585  ELAL---SGEKGDQGPPGDPGSPGSPGPAGPAGPPG-YGPQGEPGLQGTQGVPGAPGPPG 640

Query: 224  AQGLRGITGI-VGDKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGAR 282
              G RG   +     G  G  G  G PGPQG PG PG  G+ G PG  GP G+ G  G  
Sbjct: 641  EAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGI- 699

Query: 283  GIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAG-----LQGLPGVPGIPG 337
            G PG PGPKGD G PG  G  G PG  G  G PGKPG PG  G     + G PG PG PG
Sbjct: 700  GFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPG 759

Query: 338  AKGVAGEKGSTGAPGKPGQMGNSGK---------PGQQGPPGE--------VGPRGPQGL 380
             +G +GE G  G PG PG  G  G          PGQ GPPGE         GPRG QGL
Sbjct: 760  ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819

Query: 381  P---------GSRGELGPVGSPGLP-----------------------GKLGSLGSPGLP 408
            P         G RG+ GP G PG+P                       G LG  G PG P
Sbjct: 820  PGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNP 879

Query: 409  GL---------------------PGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGER 447
            G+                     PGPPG PG  G RG  G PG KG++G  G +GE G++
Sbjct: 880  GILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDK 939

Query: 448  GE---------LGDIGLPGPKGSAGNPGEPGLRGPEGS---RGLPGVEGPRGPPGPRGVQ 495
            G          +GD G PG KG AGNPGE G RG  G    +GL G+ GP GPPGPRG  
Sbjct: 940  GNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL 999

Query: 496  GEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPP 555
            G  G  G PG++G PG                      M     +   G  G PGR G P
Sbjct: 1000 GSTGNPGEPGLRGIPG------------------SMGNMGMPGSKGKRGTLGFPGRAGRP 1041

Query: 556  GPPGPPGENGFPGQMGIR--GLPGIKGPPGALGLRGPKGDLGEKGERGPPG-------RG 606
            G PG  G  G  G+ G      PG  GP G  GL G  G  GE G+ GPPG        G
Sbjct: 1042 GLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEG 1101

Query: 607  PNGLPGAIGLPGDPGP-ASYGRNGRDGERGPPGVAGIPGVPGPPGPPGLPG 656
              G PG+ GLPG PGP    G  G  G  GPPG+ G PG+PG PG PG  G
Sbjct: 1102 APGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMG 1152



 Score =  488 bits (1256), Expect = e-138
 Identities = 303/687 (44%), Positives = 340/687 (49%), Gaps = 107/687 (15%)

Query: 24   QRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPG--APGKPGTPGA 81
            +RG  GE G  G PG PG+PG  G +G  GP+G PG PGP GE G PG    G  G  G 
Sbjct: 760  ERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGL 819

Query: 82   DGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPGRGIPGPPGPPGTAGLPGELGRVGPVGDP 141
             GL G  G  G  G  G KG+PG+P   G    G PG  G PG  G  GE+G +G  G P
Sbjct: 820  PGLNGLKGQQGRRGKTGPKGDPGIP---GLDRSGFPGETGSPGIPGHQGEMGPLGQRGYP 876

Query: 142  GRRGPPGPPGPPGPRGTIGFHDGDPLCPNAC-PPGRSGYPGLPGMRGHKGAKGEIGEPGR 200
            G  G  GPPG  G  G +GF       P A  PPG  G PG PG RG  G  G  G+ G 
Sbjct: 877  GNPGILGPPGEDGVIGMMGF-------PGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGT 929

Query: 201  QGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGD 260
             G KGE+GD+G  G        G +G  G+ G  G+ GEKG RG+ G PG +GL G PG 
Sbjct: 930  PGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGP 989

Query: 261  QGQRGPPGEAGPKGDRGAEGARGIP------GLPGPKGDTGLPGVDGRDGIPGMP----- 309
             G  GP G+ G  G+ G  G RGIP      G+PG KG  G  G  GR G PG+P     
Sbjct: 990  AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGL 1049

Query: 310  -GTKGEPG-----KPGPPGDAGLQGLP------GVPGIPGAKGVAGEKGSTGAPGKPGQM 357
             G KGEPG     +PGPPG  G  GLP      G  G PG  G  G  G  GAPG PG  
Sbjct: 1050 QGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSP 1109

Query: 358  GNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGSPGLPGKLGSLGSPGLPGLPGP---- 413
            G  GKPG  G  G  G +G  G PG RG  G  G PG PG +G  G  G  G+PGP    
Sbjct: 1110 GLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEK 1169

Query: 414  ---------------PGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGP 458
                           PG  G KGDRG  G PG  G +GA    G+AG RG  G  G PGP
Sbjct: 1170 GETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAM---GDAGPRGPTGIEGFPGP 1226

Query: 459  KGSAGN--PGEPGLRGPEGSRGLPGVEGPRGPPGPR--GVQGEQGATGLPGVQGPPGRAP 514
             G  G   PG+ G RGP GSRG PG  GP GPPG    G++G++G+ G PG +GPPG A 
Sbjct: 1227 PGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTA- 1285

Query: 515  TDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRG 574
                                         G  G PGR G PG PG PG  G PG  G  G
Sbjct: 1286 -----------------------------GDMGPPGRLGAPGTPGLPGPRGDPGFQGFPG 1316

Query: 575  LPGIKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLPGAIGLPGDPGPASYGRNGRDGE 633
            + G KG PG LG  GP G +G K   GPPG RG  G    I LPG PGP           
Sbjct: 1317 VKGEKGNPGFLGSIGPPGPIGPK---GPPGVRGDPGTLKIISLPGSPGPP---------- 1363

Query: 634  RGPPGVAGIPGVPGPPGPPGLPGFCEP 660
             G PG  G+ G PGPPGPPG  G C P
Sbjct: 1364 -GTPGEPGMQGEPGPPGPPGNLGPCGP 1389



 Score =  484 bits (1245), Expect = e-136
 Identities = 308/736 (41%), Positives = 372/736 (50%), Gaps = 127/736 (17%)

Query: 17  GLCLCAAQRGPPGEQGPPGPPGPPGVPGI---DGIDGDRGPKGPPGPPGPAGE------- 66
           G C C   +G  GE+G PGPPG PG  G    +G+ G +GPKG PG PG  G        
Sbjct: 37  GQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGIS 96

Query: 67  --PGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSRGFPG----------- 113
             PG  G+PG PGTPG  G  G  G PG  GSKG++G PG+PG+ G+PG           
Sbjct: 97  GLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQK 156

Query: 114 -------------RGIPGPPGPPGTAGLPGELGRVGPVGDPGRRGPPGPPGPPGPRGTIG 160
                        +G PG PG PG  GLPG  G  GPVG PG  G  G PG  GPRG  G
Sbjct: 157 GAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216

Query: 161 FHDGDPLCPNACPPGRSGYPGLPGMRGHKGAKGEI-----GEPGRQGHKGEEGDQGELGE 215
            H G+ +       G  G  G+ G+ G  G  G +     G   R   KGE+GD+G +GE
Sbjct: 217 -HMGERVI------GHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGE 269

Query: 216 VGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEPGPQGLPGAPGDQ---GQRGPPGEAGP 272
               GPPG  GL G      +KG  G  GL G+PG  G+PG PG +   G RG PG  G 
Sbjct: 270 ---PGPPGPSGLPG-ESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGE 325

Query: 273 KGDRGAEGARGIPGLPGP---------KGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGD 323
            G +G +G  G PG  GP         KGD G PG  G  G  G  G  G PG PG PG 
Sbjct: 326 DGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGS 385

Query: 324 A--GLQGLPGVPGIPGAKGVAGEKG--STGAPGKPGQMGNSGKPGQQGPPGEVGP----R 375
           +  GL+G PG PG+ G+KG  G  G  + G PG PG  G+ G PG  GPPG  G     +
Sbjct: 386 SRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRK 445

Query: 376 GPQGLPGSRGELGPVGSPGLPGKLGSLGSPGL-----PGLPGPPGLPGMKGDRGVVGEPG 430
           GP   PG  G  G +GSPG+PG  G  G PGL     P +PGPPGLPG+ G  GV G P 
Sbjct: 446 GP---PGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIP- 501

Query: 431 PKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRG----PEGSRGLPGVEGPR 486
             G QGA+G +G  G  G  G  G PG  G+ G+PG  G +G    PEG  G+PG  G R
Sbjct: 502 --GRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLR 559

Query: 487 GPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGAT 546
           G PG +G+ G  G  G+ G+ GP G                     E+A S ++ D G  
Sbjct: 560 GQPGRKGLDGIPGTPGVKGLPGPKG---------------------ELALSGEKGDQGPP 598

Query: 547 GLPGRPGPPGPPGPPGENGF--PGQMGIRGLPGIKGPPGALGLRGPKGDL-------GEK 597
           G PG PG PGP GP G  G+   G+ G++G  G+ G PG  G  GP+G+L       G  
Sbjct: 599 GDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPP 658

Query: 598 GERGPPG----RGPNGLPGAIGLPGDPGPASYGRNGRDGERGPPGVAGIPGVPGPPGPPG 653
           G  GPPG    +GP G+PG++G  GDP     G  G DGE G PG+ G PG PGP G  G
Sbjct: 659 GPPGPPGHPGPQGPPGIPGSLGKCGDP-----GLPGPDGEPGIPGI-GFPGPPGPKGDQG 712

Query: 654 LPGFCEPASCTMQAGQ 669
            PG      C  + G+
Sbjct: 713 FPGTKGSLGCPGKMGE 728



 Score =  476 bits (1225), Expect = e-134
 Identities = 310/765 (40%), Positives = 374/765 (48%), Gaps = 144/765 (18%)

Query: 15  LLGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRG-----------PKGPPGPPGP 63
           L+G+  C+  +G  G  G PG  G PG+PG  G+ G +G            KG PG PG 
Sbjct: 119 LVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGA 178

Query: 64  AGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPG--VPGSRGFPG-RGIPGPP 120
            G  G PG PG PG  G  G  G  G PG++G +G KG  G  V G +G  G +G+ GPP
Sbjct: 179 PGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPP 238

Query: 121 GPPGT-----------AGLPGELGRVGPVGDPGRRGP-----------PGPPGPPGPRGT 158
           GPPGT             L GE G  G +G+PG  GP            G PG PG +G 
Sbjct: 239 GPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGK 298

Query: 159 IGFHDGDPLCPNA-CPPGRSGYPGLPGMRGHKGAKGEIGEPGRQG---------HKGEEG 208
            G  DG P  P +    G  G+PGL G  G KG KG+IG PG +G          KG+EG
Sbjct: 299 PG-KDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEG 357

Query: 209 DQGELGEVGAQGP-----------------PGAQGLRGITGIVGDKGEKG-----ARGLD 246
             G  G  GA+GP                 PG +G  G  G+ G KGE+G     A G  
Sbjct: 358 TPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTP 417

Query: 247 GEPGPQGLPGAPGDQGQRGPPGE----AGPKGDRGAE---GARGIPGLPGPKGDTGL--- 296
           G PG  G PG PG  G  GPPG+     GP GD G     G+ GIPG+ GPKG+ GL   
Sbjct: 418 GSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCT 477

Query: 297 -----PGVDGRDGIPGMPGTKGEPGK---------PGPPGDAGLQGLPGVPGIPGAKGVA 342
                PG  G  G+PG+ G KG PG+         PG PG+ GL G PG PG  G  G+ 
Sbjct: 478 QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK 537

Query: 343 GEKGST-------GAPGKPGQMGNSGKPGQQGPPGE------VGPRGPQGLPGSRGELGP 389
           GEKG T       G PG PG  G  G+ G  G PG        GP+G   L G +G+ GP
Sbjct: 538 GEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGP 597

Query: 390 VGSPGLPGKLGSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGE--------- 440
            G PG PG  G  G  G PG  GP G PG++G +GV G PGP GE G  GE         
Sbjct: 598 PGDPGSPGSPGPAGPAGPPGY-GPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPG 656

Query: 441 -EGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGV--EGPRGPPGPRGVQGE 497
             G  G  G  G  G PG  GS G  G+PGL GP+G  G+PG+   GP GP G +G  G 
Sbjct: 657 PPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGT 716

Query: 498 QGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGP 557
           +G+ G PG  G PG                      +  +   P   A  +PG PG PG 
Sbjct: 717 KGSLGCPGKMGEPGLPGK----------------PGLPGAKGEP---AVAMPGGPGTPGF 757

Query: 558 PGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLGE---KGERGPPGRGPNGLPGAI 614
           PG  G +G  G++G+ GLPG+ G PG  GL GP+GD G+    GE+GPPGR   G  GA 
Sbjct: 758 PGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQ 817

Query: 615 GLPGDPG-PASYGRNGRDGERGPPGVAGI--PGVPGPPGPPGLPG 656
           GLPG  G     GR G+ G +G PG+ G+   G PG  G PG+PG
Sbjct: 818 GLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPG 862



 Score =  463 bits (1192), Expect = e-130
 Identities = 293/695 (42%), Positives = 343/695 (49%), Gaps = 134/695 (19%)

Query: 24   QRGPPGEQGPPG-----PPGPPGVPGIDGIDGDRG------PKGPPGPPG---------- 62
            Q GPPGEQGPPG     P G  G+PG++G+ G +G      PKG PG PG          
Sbjct: 796  QPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGET 855

Query: 63   -------------PAGEPGKPGAPGKPGTPGADGLTGPDGSPGSIGSKGQKGEPGVPGSR 109
                         P G+ G PG PG  G PG DG+ G  G PG+IG  G  G PG PG R
Sbjct: 856  GSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQR 915

Query: 110  GFPG-------------------RGIPGP------------PGPPGTAGLPGELGRVGPV 138
            G PG                   +G PGP            PG  G AG PGE G  G  
Sbjct: 916  GSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVP 975

Query: 139  GDPGRRGP---PGPPGPPGPRGTIGFHDGDPLCPNACP-PGRSGYPGLPGMRGHKGAKGE 194
            G PG +G    PGP GPPGPRG +G   G+P  P     PG  G  G+PG +G +G  G 
Sbjct: 976  GMPGLKGLKGLPGPAGPPGPRGDLG-STGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGF 1034

Query: 195  IGEPGRQGHKGEEGDQGELGEVGAQ-----GPPGAQGLRGITGIVGDKGEKGARGLDGEP 249
             G  GR G  G  G QG+ GE G       GPPG  G  G+ G +G KGE G  G  G  
Sbjct: 1035 PGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHL 1094

Query: 250  GPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMP 309
            GP G  GAPG  G  G PG+ GP GD G +G +G+ G PG +G  GLPG  G  G  G+ 
Sbjct: 1095 GPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIR 1154

Query: 310  GTKGEPGKPGPPGDAGLQGL----PGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQ 365
            G +G  G PGP G+ G  GL    PG  G PGA+G  G++G+ G PG PG+ G  G  G 
Sbjct: 1155 GDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGP 1214

Query: 366  QGPPGEVGPRGPQGLPGS--RGELGPVGSPGLPGKLGSLGSPGLPGLPGPPG--LPGMKG 421
            +GP G  G  GP GLPG+   G+ G  G PG      S GSPG PG PGPPG  + G+KG
Sbjct: 1215 RGPTGIEGFPGPPGLPGAIIPGQTGNRGPPG------SRGSPGAPGPPGPPGSHVIGIKG 1268

Query: 422  DRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGL-- 479
            D+G +G PGPKG  G +G+ G  G  G  G  GLPGP+G  G  G PG++G +G+ G   
Sbjct: 1269 DKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLG 1328

Query: 480  ----PGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMA 535
                PG  GP+GPPG RG  G      LPG  GPPG                        
Sbjct: 1329 SIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGT----------------------- 1365

Query: 536  ASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGPKGDLG 595
                         PG PG  G PGPPG  G  G  G RG PG  G PG  G  G KG+ G
Sbjct: 1366 -------------PGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKG 1412

Query: 596  EKGERGPPGRGPNGLPGAIGLPGDPG-PASYGRNG 629
             KGE GP   G +GLPG  G  GD G PA++   G
Sbjct: 1413 SKGEPGP--AGSDGLPGLKGKRGDSGSPATWTTRG 1445



 Score =  337 bits (865), Expect = 2e-92
 Identities = 202/486 (41%), Positives = 237/486 (48%), Gaps = 87/486 (17%)

Query: 26   GPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGADGLT 85
            G PGE+G  G PG PG+ G+ G+ G  GP GP G  G  G PG+PG  G PG+ G  G+ 
Sbjct: 964  GNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMP 1023

Query: 86   GPDGSPGSIGSKGQKGEPGVPGSRGFPG--------RGI-PGPPGPPGTAGLPGELGR-- 134
            G  G  G++G  G+ G PG+PG  G  G         G  PGPPGP G  GLPG++G+  
Sbjct: 1024 GSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKG 1083

Query: 135  -------------VGPVGDPGRRGPPGPPGPPGPRGTIGFHD-----GDPLCPNACPPGR 176
                          GP G PG  G PG PG PGP G +GF       G P      PPG 
Sbjct: 1084 EMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRG--PPGL 1141

Query: 177  SGYPGLPGMRGHKGAKGEIGEPGRQGHKGE----------EGDQGELGEVGAQGPPGAQG 226
             G+PG PG  G +G +G  G PG  G KGE           G+ G  G  G +G PG  G
Sbjct: 1142 PGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPG 1201

Query: 227  LRGITGIVGDKGEKGARGLDGEPGPQGLPGA--PGDQGQRGPPGEAGP------------ 272
            L G  G +GD G +G  G++G PGP GLPGA  PG  G RGPPG  G             
Sbjct: 1202 LPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGS 1261

Query: 273  -----KGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPG----------- 316
                 KGD+G+ G  G  G PG  GD G PG  G  G PG+PG +G+PG           
Sbjct: 1262 HVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEK 1321

Query: 317  -------KPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPP 369
                     GPPG  G +G PGV G PG   +    GS G PG PG+ G  G+PG  GPP
Sbjct: 1322 GNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPP 1381

Query: 370  GEVGPRGPQGLPGS---------RGELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPGMK 420
            G +GP GP+G PG           GE G  GS G PG  GS G PGL G  G  G P   
Sbjct: 1382 GNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSPATW 1441

Query: 421  GDRGVV 426
              RG V
Sbjct: 1442 TTRGFV 1447



 Score =  335 bits (859), Expect = 8e-92
 Identities = 226/562 (40%), Positives = 269/562 (47%), Gaps = 82/562 (14%)

Query: 190 GAKGEIGEPGRQGHKGEEGDQGELGEVGAQGPPGAQGLRGITGIVGDKGEKGARGLDGEP 249
           GAKGE GE   +G  G  G  G+ G  G +G PG QG +G  G+ G  G KG RG+ G P
Sbjct: 43  GAKGEKGE---KGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLP 99

Query: 250 GPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTGLPGVDGRDGIPGMP 309
           G  G PG PG  G  GP G  G  G  G++G +G PGLPG  G  G+PG  G  G  G P
Sbjct: 100 GFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAP 159

Query: 310 G--------TKGEPGKPGPPGDAGLQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSG 361
                     KG+PG PG PG    QGLPG PG PG  G  G  G  G PG  G  G  G
Sbjct: 160 AKEEDIELDAKGDPGLPGAPGP---QGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKG 216

Query: 362 KPGQQ--GPPGEVGPRGPQGLPGSRGEL-----GPVGSPGLPGKLGSLGSPGLPGLPGPP 414
             G++  G  GE G +G  G PG  G +     GP     L G+ G  G+ G PG PGP 
Sbjct: 217 HMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPS 276

Query: 415 GLPGMK--------GDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPKGSAGNPG 466
           GLPG          GD G+ G+PG  G  G  G EG  G RG  G +G  G KG  G+ G
Sbjct: 277 GLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIG 336

Query: 467 EPGLRGPE---GSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGR-------APTD 516
            PG RGP     +    G EG  GPPGPRG +G QG +G PGV G PG        AP  
Sbjct: 337 PPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGW 396

Query: 517 QHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPG-------PPGENGFPGQ 569
             +K       +     M        +G+ GLPG PGPPGPPG       PPG++G PG 
Sbjct: 397 PGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGY 456

Query: 570 MGIRGLPG-----------------IKGPPGALGLRGPKGDLGEKGERGPPG-RGPNGLP 611
           +G  G+PG                 I GPPG  GL G  G  G  G +G  G +G  G P
Sbjct: 457 LGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSP 516

Query: 612 GAIGLPGDPG-PASYGRNGRDGERG----PPGVAGIPGVPGP------------PGPPGL 654
           G  GLPG PG P + G  G  GE+G    P G  G+PG PG             PG PG+
Sbjct: 517 GNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGV 576

Query: 655 PGFCEPASCTMQAGQRAFNKGP 676
            G   P      +G++  ++GP
Sbjct: 577 KGLPGPKGELALSGEKG-DQGP 597



 Score =  317 bits (812), Expect = 2e-86
 Identities = 210/533 (39%), Positives = 248/533 (46%), Gaps = 113/533 (21%)

Query: 236 DKGEKGARGLDGEPGPQGLPGAPGDQGQRGPPGEAGPKGDRGAEGARGIPGLPGPKGDTG 295
           DKG+    G  GE G +G PG PG  GQ+G  G  G  G +G +G  G+PGL G KG  G
Sbjct: 35  DKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRG 94

Query: 296 LPGVDGRDGIPGMPGTKGE---------PGKPGPPGDAGLQGLPGV---PGIPGAKGVAG 343
           + G+ G  G PG+PGT G          PG  G  G+ G  GLPG    PGIPGA G+ G
Sbjct: 95  ISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKG 154

Query: 344 EKG-----------STGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRGELGPVGS 392
           +KG           + G PG PG  G  G PG  G PG VGP GP G  G  G +GP G 
Sbjct: 155 QKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGP 214

Query: 393 PGLPGK--LGSLGSPGLPGLPGPPGLPGM-----------------KGDRGVVGEPGPKG 433
            G  G+  +G  G  G+ GL GPPG PG                  KGD+G +GEPGP G
Sbjct: 215 KGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274

Query: 434 EQGASGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLRGPEGSRGLPGV----------- 482
             G  G E    E+G  GD GL G  G  G PG PG  G +G+RG PG+           
Sbjct: 275 PSGLPG-ESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKG 333

Query: 483 ----------------------EGPRGPPGPRGVQGEQGATGLPGVQGPPGR-------A 513
                                 EG  GPPGPRG +G QG +G PGV G PG        A
Sbjct: 334 DIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGA 393

Query: 514 PTDQHIKQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPP-------GPPGENGF 566
           P    +K       +     M        +G+ GLPG PGPPGPP       GPPG++G 
Sbjct: 394 PGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGL 453

Query: 567 PGQMGIRGLPG-----------------IKGPPGALGLRGPKGDLGEKGERGPPG-RGPN 608
           PG +G  G+PG                 I GPPG  GL G  G  G  G +G  G +G  
Sbjct: 454 PGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSP 513

Query: 609 GLPGAIGLPGDPG-PASYGRNGRDGERG----PPGVAGIPGVPGPPGPPGLPG 656
           G PG  GLPG PG P + G  G  GE+G    P G  G+PG PG  G PG  G
Sbjct: 514 GSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKG 566



 Score =  258 bits (658), Expect = 2e-68
 Identities = 182/459 (39%), Positives = 207/459 (45%), Gaps = 86/459 (18%)

Query: 270 AGPKGDRGA----EGARGIPGLPGPKGDTGLPGVDGRDGIPGMPGTKGEPGKPGPPGDAG 325
           A P   +G     +G     G  G KG+ G PG       PG PG KG  G  G PG  G
Sbjct: 23  AAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGP------PGSPGQKGFTGPEGLPGPQG 76

Query: 326 LQGLPGVPGIPGAKGVAGEKGSTGAPGKPGQMGNSGKPGQQGPPGEVGPRGPQGLPGSRG 385
            +G PG+PG+ G+KGV   +G +G PG       SG PG  G PG  GP G  G+PG  G
Sbjct: 77  PKGFPGLPGLTGSKGV---RGISGLPGF------SGSPGLPGTPGNTGPYGLVGVPGCSG 127

Query: 386 ELGPVGSPGLPGKLGSLGSPGLPGLPGPPGLPG--------MKGDRGVVGEPGPKGEQGA 437
             G  G PGLPG LG  G PG  GL G  G P          KGD G+ G PGP+G  G 
Sbjct: 128 SKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGP 187

Query: 438 SGEEGEAGERGELGDIGLPGPKGSAGNPGEPGLR--GPEGSRGLPGVEGPRGPPGP---- 491
            G  G  G  G  G  G PG  G  G  G  G R  G +G RG+ G+ GP GPPG     
Sbjct: 188 PGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVT 247

Query: 492 ----------RGVQGEQGATGLPGVQGPPGRAPTDQHIKQVCMRVIQEHFAEMAASLKRP 541
                     +G +G++GA G PG  GP G                + + +E  A     
Sbjct: 248 LTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPG-------------ESYGSEKGAP---G 291

Query: 542 DSGATGLPGR---PGPPGPPGPPGENGFPGQMGIRGLPGIKGPPGALGLRGP-------- 590
           D G  G PG+   PG PG  G  G  GFPG MG  G+ G KG  G  G RGP        
Sbjct: 292 DPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQ 351

Query: 591 -KGDLGEKGERGPPG-RGPNGLPGAIGLPGDPG---------PASYGRNGRDGERGPPG- 638
            KGD G  G  GP G RGP G  G  G+PG PG         P   G  G  GERG PG 
Sbjct: 352 EKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGK 411

Query: 639 -VAGIPGVPGPPGPPGLPGFCEPASCTMQAGQRAFNKGP 676
              G PG PG  G PGLPG   P       G   F KGP
Sbjct: 412 DAMGTPGSPGCAGSPGLPGSPGPPG---PPGDIVFRKGP 447



 Score =  185 bits (469), Expect = 1e-46
 Identities = 125/328 (38%), Positives = 145/328 (44%), Gaps = 55/328 (16%)

Query: 400 GSLGSPGLPGLPGPPGLPGMKGDRGVVGEPGPKGEQGASGEEGEAGERGELGDIGLPGPK 459
           G+ G  G  G PGPPG PG KG  G  G PGP+G +G  G  G  G +G  G  GLPG  
Sbjct: 43  GAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFS 102

Query: 460 GSAGNPGEPGLRGPEGSRGLPGVEGPRGPPGPRGVQGEQGATGLPGVQGPPGRAPTDQHI 519
           GS G PG PG  GP G  G+PG  G +G  G  G+ G  G  G+PG  G  G+       
Sbjct: 103 GSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKE 162

Query: 520 KQVCMRVIQEHFAEMAASLKRPDSGATGLPGRPGPPGPPGPPGENGFPGQMGIRG----- 574
           + + +    +     A        G  G PG PGP GPPGPPG  GFPG MG RG     
Sbjct: 163 EDIELDAKGDPGLPGAPG----PQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHM 218

Query: 575 ------------LPGIKGPPGALG--------------LRGPKGDLGEKGERGPPGRGPN 608
                       + G+ GPPG  G              L+G KGD G  GE GPPG  P+
Sbjct: 219 GERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG--PS 276

Query: 609 GLPGAI-----GLPGDPG----------PASYGRNGRDGERGPPGVAGIPGVPGPP---G 650
           GLPG       G PGDPG          P   G  G  G RG PG+ G  G+ G     G
Sbjct: 277 GLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIG 336

Query: 651 PPGLPGFCEPASCTMQAGQRAFNKGPDP 678
           PPG  G  E      + G       P P
Sbjct: 337 PPGFRGPTEYYDTYQEKGDEGTPGPPGP 364



 Score =  125 bits (313), Expect = 2e-28
 Identities = 87/246 (35%), Positives = 101/246 (41%), Gaps = 77/246 (31%)

Query: 25   RGPPGEQGPPGPPGPPGVPG--IDGIDGDRGPKGPPGPPGPAGEPGKPGAPGKPGTPGAD 82
            RGPPG +G PG PGPPG PG  + GI GD+G  G PGP GP G  G  G PG+ G PG  
Sbjct: 1241 RGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTP 1300

Query: 83   GLTGPDGSPGSIGS---KGQKGEPGV---------------PGSRGFPGR----GIPGPP 120
            GL GP G PG  G    KG+KG PG                PG RG PG      +PG P
Sbjct: 1301 GLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSP 1360

Query: 121  GPPGTAGLPGELGRVGPVGDPG-------------------------------------- 142
            GPPGT G PG  G  GP G PG                                      
Sbjct: 1361 GPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPA 1420

Query: 143  ----------RRGPPGPPGPPGPRGTIGFHDGD----PLCPNACPPGRSGYPGLPGMRGH 188
                      +RG  G P     RG +          P CP    P  SG+  L  ++G+
Sbjct: 1421 GSDGLPGLKGKRGDSGSPATWTTRGFVFTRHSQTTAIPSCPEGTVPLYSGFSFL-FVQGN 1479

Query: 189  KGAKGE 194
            + A G+
Sbjct: 1480 QRAHGQ 1485



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 26/66 (39%), Positives = 31/66 (46%), Gaps = 12/66 (18%)

Query: 16   LGLCLCAAQRGPPGEQGPPGPPGPPGVPGIDGIDGDRGPKGPPGPPGPAGEPGKPGAPGK 75
            LG C    + G  G+ G PGP             G++G KG  G PGPAG  G PG  GK
Sbjct: 1384 LGPCGPRGKPGKDGKPGTPGPA------------GEKGNKGSKGEPGPAGSDGLPGLKGK 1431

Query: 76   PGTPGA 81
             G  G+
Sbjct: 1432 RGDSGS 1437


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.148    0.481 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 56,895,910
Number of Sequences: 37866
Number of extensions: 5311631
Number of successful extensions: 235033
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 613
Number of HSP's successfully gapped in prelim test: 1580
Number of HSP's that attempted gapping in prelim test: 17135
Number of HSP's gapped (non-prelim): 26634
length of query: 678
length of database: 18,247,518
effective HSP length: 109
effective length of query: 569
effective length of database: 14,120,124
effective search space: 8034350556
effective search space used: 8034350556
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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