BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|72256200 B-cell CLL/lymphoma 9 [Homo sapiens] (1426 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|72256200 B-cell CLL/lymphoma 9 [Homo sapiens] 2967 0.0 gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens] 683 0.0 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 129 2e-29 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 127 8e-29 gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 126 1e-28 gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 115 2e-25 gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s... 113 1e-24 gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 113 1e-24 gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 113 1e-24 gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s... 113 1e-24 gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] 112 2e-24 gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 112 2e-24 gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 112 3e-24 gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 112 3e-24 gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 112 3e-24 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 112 3e-24 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 106 1e-22 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 105 4e-22 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 105 4e-22 gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 103 9e-22 gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] 102 2e-21 gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] 102 2e-21 gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo ... 101 4e-21 gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo s... 101 4e-21 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 101 6e-21 gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 101 6e-21 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 99 4e-20 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 99 4e-20 gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] 94 1e-18 gi|163965366 nascent polypeptide-associated complex alpha subuni... 91 8e-18 >gi|72256200 B-cell CLL/lymphoma 9 [Homo sapiens] Length = 1426 Score = 2967 bits (7692), Expect = 0.0 Identities = 1426/1426 (100%), Positives = 1426/1426 (100%) Query: 1 MHSSNPKVRSSPSGNTQSSPKSKQEVMVRPPTVMSPSGNPQLDSKFSNQGKQGGSASQSQ 60 MHSSNPKVRSSPSGNTQSSPKSKQEVMVRPPTVMSPSGNPQLDSKFSNQGKQGGSASQSQ Sbjct: 1 MHSSNPKVRSSPSGNTQSSPKSKQEVMVRPPTVMSPSGNPQLDSKFSNQGKQGGSASQSQ 60 Query: 61 PSPCDSKSGGHTPKALPGPGGSMGLKNGAGNGAKGKGKRERSISADSFDQRDPGTPNDDS 120 PSPCDSKSGGHTPKALPGPGGSMGLKNGAGNGAKGKGKRERSISADSFDQRDPGTPNDDS Sbjct: 61 PSPCDSKSGGHTPKALPGPGGSMGLKNGAGNGAKGKGKRERSISADSFDQRDPGTPNDDS 120 Query: 121 DIKECNSADHIKSQDSQHTPHSMTPSNATAPRSSTPSHGQTTATEPTPAQKTPAKVVYVF 180 DIKECNSADHIKSQDSQHTPHSMTPSNATAPRSSTPSHGQTTATEPTPAQKTPAKVVYVF Sbjct: 121 DIKECNSADHIKSQDSQHTPHSMTPSNATAPRSSTPSHGQTTATEPTPAQKTPAKVVYVF 180 Query: 181 STEMANKAAEAVLKGQVETIVSFHIQNISNNKTERSTAPLNTQISALRNDPKPLPQQPPA 240 STEMANKAAEAVLKGQVETIVSFHIQNISNNKTERSTAPLNTQISALRNDPKPLPQQPPA Sbjct: 181 STEMANKAAEAVLKGQVETIVSFHIQNISNNKTERSTAPLNTQISALRNDPKPLPQQPPA 240 Query: 241 PANQDQNSSQNTRLQPTPPIPAPAPKPAAPPRPLDRESPGVENKLIPSVGSPASSTPLPP 300 PANQDQNSSQNTRLQPTPPIPAPAPKPAAPPRPLDRESPGVENKLIPSVGSPASSTPLPP Sbjct: 241 PANQDQNSSQNTRLQPTPPIPAPAPKPAAPPRPLDRESPGVENKLIPSVGSPASSTPLPP 300 Query: 301 DGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGEPPTLGENPDGLSQEQLEHRE 360 DGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGEPPTLGENPDGLSQEQLEHRE Sbjct: 301 DGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGEPPTLGENPDGLSQEQLEHRE 360 Query: 361 RSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPGVLDGPQKKPEGPIQAMMAQSQSLGKGP 420 RSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPGVLDGPQKKPEGPIQAMMAQSQSLGKGP Sbjct: 361 RSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPGVLDGPQKKPEGPIQAMMAQSQSLGKGP 420 Query: 421 GPRTDVGAPFGPQGHRDVPFSPDEMVPPSMNSQSGTIGPDHLDHMTPEQIAWLKLQQEFY 480 GPRTDVGAPFGPQGHRDVPFSPDEMVPPSMNSQSGTIGPDHLDHMTPEQIAWLKLQQEFY Sbjct: 421 GPRTDVGAPFGPQGHRDVPFSPDEMVPPSMNSQSGTIGPDHLDHMTPEQIAWLKLQQEFY 480 Query: 481 EEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPPPPYQMTPSEGWAPGGTEPFSDGINM 540 EEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPPPPYQMTPSEGWAPGGTEPFSDGINM Sbjct: 481 EEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPPPPYQMTPSEGWAPGGTEPFSDGINM 540 Query: 541 PHSLPPRGMAPHPNMPGSQMRLPGFAGMINSEMEGPNVPNPASRPGLSGVSWPDDVPKIP 600 PHSLPPRGMAPHPNMPGSQMRLPGFAGMINSEMEGPNVPNPASRPGLSGVSWPDDVPKIP Sbjct: 541 PHSLPPRGMAPHPNMPGSQMRLPGFAGMINSEMEGPNVPNPASRPGLSGVSWPDDVPKIP 600 Query: 601 DGRNFPPGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNR 660 DGRNFPPGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNR Sbjct: 601 DGRNFPPGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNR 660 Query: 661 MIPGSQRHMEPGNNPIFPRIPVEGPLSPSRGDFPKGIPPQMGPGRELEFGMVPSGMKGDV 720 MIPGSQRHMEPGNNPIFPRIPVEGPLSPSRGDFPKGIPPQMGPGRELEFGMVPSGMKGDV Sbjct: 661 MIPGSQRHMEPGNNPIFPRIPVEGPLSPSRGDFPKGIPPQMGPGRELEFGMVPSGMKGDV 720 Query: 721 NLNVNMGSNSQMIPQKMREAGAGPEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQQEYGMG 780 NLNVNMGSNSQMIPQKMREAGAGPEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQQEYGMG Sbjct: 721 NLNVNMGSNSQMIPQKMREAGAGPEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQQEYGMG 780 Query: 781 PRPFLPMSQGPGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRG 840 PRPFLPMSQGPGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRG Sbjct: 781 PRPFLPMSQGPGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRG 840 Query: 841 LGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGMLAGPA 900 LGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGMLAGPA Sbjct: 841 LGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGMLAGPA 900 Query: 901 AAASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMASPA 960 AAASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMASPA Sbjct: 901 AAASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMASPA 960 Query: 961 MLGNVESGGPPPPTASQPASVNIPGSLPSSTPYTMPPEPTLSQNPLSIMMSRMSKFAMPS 1020 MLGNVESGGPPPPTASQPASVNIPGSLPSSTPYTMPPEPTLSQNPLSIMMSRMSKFAMPS Sbjct: 961 MLGNVESGGPPPPTASQPASVNIPGSLPSSTPYTMPPEPTLSQNPLSIMMSRMSKFAMPS 1020 Query: 1021 STPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMGINTQNPRISGPNPVVPMPTLSPM 1080 STPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMGINTQNPRISGPNPVVPMPTLSPM Sbjct: 1021 STPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMGINTQNPRISGPNPVVPMPTLSPM 1080 Query: 1081 GMTQPLSHSNQMPSPNAVGPNIPPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQG 1140 GMTQPLSHSNQMPSPNAVGPNIPPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQG Sbjct: 1081 GMTQPLSHSNQMPSPNAVGPNIPPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQG 1140 Query: 1141 FPPVQSPPQQVPFPHNGPSGGQGSFPGGMGFPGEGPLGRPSNLPQSSADAALCKPGGPGG 1200 FPPVQSPPQQVPFPHNGPSGGQGSFPGGMGFPGEGPLGRPSNLPQSSADAALCKPGGPGG Sbjct: 1141 FPPVQSPPQQVPFPHNGPSGGQGSFPGGMGFPGEGPLGRPSNLPQSSADAALCKPGGPGG 1200 Query: 1201 PDSFTVLGNSMPSVFTDPDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGR 1260 PDSFTVLGNSMPSVFTDPDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGR Sbjct: 1201 PDSFTVLGNSMPSVFTDPDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGR 1260 Query: 1261 KQPQGPGPGFSHMQGMMGEQAPRMGLALPGMGGPGPVGTPDIPLGTAPSMPGHNPMRPPA 1320 KQPQGPGPGFSHMQGMMGEQAPRMGLALPGMGGPGPVGTPDIPLGTAPSMPGHNPMRPPA Sbjct: 1261 KQPQGPGPGFSHMQGMMGEQAPRMGLALPGMGGPGPVGTPDIPLGTAPSMPGHNPMRPPA 1320 Query: 1321 FLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGLYTHPGPVGSPGM 1380 FLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGLYTHPGPVGSPGM Sbjct: 1321 FLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGLYTHPGPVGSPGM 1380 Query: 1381 MMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPGNMMF 1426 MMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPGNMMF Sbjct: 1381 MMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPGNMMF 1426 >gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens] Length = 1499 Score = 683 bits (1763), Expect = 0.0 Identities = 570/1591 (35%), Positives = 758/1591 (47%), Gaps = 272/1591 (17%) Query: 5 NPKVRSSPSGNTQSSPKSKQEVMVRPPTVMSPSGNPQLDSKFSNQGKQGGSASQSQPS-- 62 +P+ R +P G+ SP+ PP P ++K +N GK G +QSQ Sbjct: 12 HPRRREAP-GSPPLSPRGHC-----PPAPAKPM---HPENKLTNHGKTGNGGAQSQHQNV 62 Query: 63 ----PCDSKS-----GGHTPKALPGPGGSMGLKNGAG-----NGAKGKGKRERSISADSF 108 C+ S G H KA + LKN + KGK KR+RS+S DS Sbjct: 63 NQGPTCNVGSKGVGAGNHGAKANQISPSNSSLKNPQAGVPPFSSLKGKVKRDRSVSVDSG 122 Query: 109 DQRDPGTPNDDSDIKE----------------------CNSADHIKSQDSQHTPHSMTPS 146 +QR+ GTP+ DS+ KE C+ D + H+ Sbjct: 123 EQREAGTPSLDSEAKEVAPRSKRRCVLERKQPYSGDEWCSGPDSEEDDKPIGATHNC--- 179 Query: 147 NATAPRSSTPSHGQTTATE--------------PTPAQ----------------KTPAKV 176 N P + P G T+ P P K P++ Sbjct: 180 NVADPAMAAPQLGPGQTTQLPLSESSVPGAPHGPPPGLRPDAPGGGGGGGGVPGKPPSQF 239 Query: 177 VYVFSTEMANKAAEAVLKGQVETIVSFHIQNISNNKTERSTAPLNTQISALRNDPKPLPQ 236 VYVF+T +AN AAEAVL+G+ ++I+++H QN+ K +++ PK P Sbjct: 240 VYVFTTHLANTAAEAVLQGRADSILAYHQQNVPRAKLDQA--------------PKVPPT 285 Query: 237 QPPAPANQDQNSSQNTRLQPTPPIPAPAPKPAAPPRPLDRESPGVENKLIP-SVGSPASS 295 P P + + ++ P PP P PAP A P P + L P SVG A+S Sbjct: 286 PEPLPLSTPSAGTPQSQPPPLPPPPPPAPGSAPPALPPEGPPEDSSQDLAPNSVG--AAS 343 Query: 296 TPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGEPPTLGENP----DGL 351 T GT PN+ A P+ G + SSA P P + P G+ +GL Sbjct: 344 TGGGTGGTHPNTPTATTANNPLPPGGDPSSA----PGPALLGEAAAPGNGQRSLVGSEGL 399 Query: 352 SQEQLEHRERSLQTLRDIQRMLFP--DEKEFT-----GAQSGGP--------QQNPGVLD 396 S+EQLEHRERSLQTLRDI+R+L + + F GA GGP QQ P Sbjct: 400 SKEQLEHRERSLQTLRDIERLLLRSGETEPFLKGPPGGAGEGGPPAQAPPPPQQPPTAPP 459 Query: 397 GPQKKPEGPIQAMMAQSQSLGKGPGPRTDVGAPFGPQGHRDVP-FSPDEMVPPSMNSQSG 455 KK E P+Q+M++Q+QSLG GP +VP P + MN Sbjct: 460 SGLKKYEEPLQSMISQTQSLG-------------GPPLEHEVPGHPPGGDMGQQMNMMIQ 506 Query: 456 TIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCS-LQDMMVHQHGPRGV-VRG 513 +G D L TPEQ+AW KLQ+E+YEEKRRK+EQ+ + LQDMM G G+ VRG Sbjct: 507 RLGQDSL---TPEQVAWRKLQEEYYEEKRRKEEQIGLHGSRPLQDMM----GMGGMMVRG 559 Query: 514 PPPPYQMTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPN--MPGSQM-RLPGFAGMIN 570 PPPPY P + W PG +++ + RG P P PG+Q+ R+PGF GM + Sbjct: 560 PPPPYHSKPGDQWPPGMGAQLRGPMDVQDPMQLRGGPPFPGPRFPGNQIQRVPGFGGMQS 619 Query: 571 SEMEGPNVPNPASRPGLSGVSWPDDVPKIPDGRNFPPGQGIF-SGPGRGERFPNPQGLSE 629 ME P N RP G+ W +D+P + NF + G G ERF P+ + E Sbjct: 620 MPMEVPM--NAMQRPVRPGMGWTEDLPPMGGPSNFAQNTMPYPGGQGEAERFMTPR-VRE 676 Query: 630 EMFQQQLAEKQ-LGL--PPGMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIFPRIPVEG-- 684 E+ + QL EK+ +G+ P GMA G+ SMEM RM+ + R M+P +FP G Sbjct: 677 ELLRHQLLEKRSMGMQRPLGMAGSGMGQSMEMERMMQ-AHRQMDPA---MFPGQMAGGEG 732 Query: 685 ----PLSPSRGDFPKGIPPQMGPG--RELEFGMVPSG--MKGDVNLNVNMGSNSQMIPQK 736 P+ G + P MG RE++ M P M +VN+N+NM N QM PQ+ Sbjct: 733 LAGTPMGMEFGGGRGLLSPPMGQSGLREVDPPMGPGNLNMNMNVNMNMNMNLNVQMTPQQ 792 Query: 737 --------------MREAGAGPEEMLKLRPGGSD--MLPAQQKMVPLPFGEHPQQEYGMG 780 M G PEEM ++R S M Q+ ++P F QQ + G Sbjct: 793 QMLMSQKMRGPGDLMGPQGLSPEEMARVRAQNSSGVMGGPQKMLMPSQFPNQGQQGFSGG 852 Query: 781 PRPFLPMSQGPGSNSGLRNLREPIGPDQRT-------NSRLSHMPPLPLNPSSNPT-SLN 832 P+ MSQ G N ++ PDQ + +RLSHMP L P+SNP +++ Sbjct: 853 QGPYQAMSQDMG------NTQDMFSPDQSSMPMSNVGTTRLSHMP---LPPASNPPGTVH 903 Query: 833 TAPPVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQL 892 +AP RGLGR+P D++++ +Q+ SPG+ LKSPT+ QV SP++ SPS NLKSPQTPSQ+ Sbjct: 904 SAP--NRGLGRRPSDLTISINQMGSPGMGHLKSPTLSQVHSPLVTSPSANLKSPQTPSQM 961 Query: 893 AGMLAGPAA--AASIKSPPVLGSAAA------SPVHLKSPSLPAPSPGWTSSPKPPLQSP 944 + P+A +KSP VLGS+ + SP LKSPS+ PSPGW +SPK + SP Sbjct: 962 VPL---PSANPPGPLKSPQVLGSSLSVRSPTGSPSRLKSPSMAVPSPGWVASPKTAMPSP 1018 Query: 945 GIPPNHKAPLTMASPAMLGNVESGGPPPP----TASQPASVNIPGSLPSSTPYTMPPEPT 1000 G+ N + PL M S L N+E G PP ++S P + G + S P+T P+PT Sbjct: 1019 GVSQNKQPPLNMNSSTTLSNMEQGTLPPSGPRSSSSAPPANPPSGLMNPSLPFTSSPDPT 1078 Query: 1001 LSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMGINT 1060 SQNPLS+MM++MSK+AMPSSTPLYH+AIKT+A+SDD+ P R P LP G G Sbjct: 1079 PSQNPLSLMMTQMSKYAMPSSTPLYHNAIKTIATSDDELLPDR-PLLPPPPPPQGSGPGI 1137 Query: 1061 QNPRISGPNPVVPMPTLSPMGMT----QPLSHS---NQMPSPNAVGPNIPPHGVPMGPGL 1113 N + S + + SPMGM QPLSH +PSP +G NIP H G G Sbjct: 1138 SNSQPSQMH-LNSAAAQSPMGMNLPGQQPLSHEPPPAMLPSPTPLGSNIPLHPNAQGTGG 1196 Query: 1114 MSHNPIM----GHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPSGGQG---SFP 1166 N +M G S P P FPP P P G GG G +P Sbjct: 1197 PPQNSMMMAPGGPDSLNAPCGPVPSSSQMMPFPPRLQQPHGAMAPTGGGGGGPGLQQHYP 1256 Query: 1167 GGMGFPGEG-PLGRPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVIR 1225 GM P E P P +P G G VL + SV DP+L EVIR Sbjct: 1257 SGMALPPEDLPNQPPGPMPPQQHLMGKAMAGRMGDAYPPGVL-PGVASVLNDPELSEVIR 1315 Query: 1226 PGATGIPEFDLSRIIPSEKPSQTLQYFPRGE-VPGRKQPQGPGPGFSHMQGMMGEQAPRM 1284 P TGIPEFDLSRIIPSEKPS TLQYFP+ E P + QP P ++Q MM EQ P Sbjct: 1316 PTPTGIPEFDLSRIIPSEKPSSTLQYFPKSENQPPKAQP--PNLHLMNLQNMMAEQTPSR 1373 Query: 1285 GLALPGMGGPGPVGTPDIPLGTAPSM--PGHNPM--RPPAFLQQGMM--GPHHRMMSPAQ 1338 LPG G + G SM PG + R QQGM+ G H +MSP Q Sbjct: 1374 PPNLPGQQG--------VQRGLNMSMCHPGQMSLLGRTGVPPQQGMVPHGLHQGVMSPPQ 1425 Query: 1339 STMPGQPTLMSNPAAAVGMIPGKDRGPAG-LYTHPGPVGSPGMMMSMQGMMG--PQQNIM 1395 M Q ++ K RG G +Y+ P P M+ +MG PQQN+M Sbjct: 1426 GLMTQQNFMLM-----------KQRGVGGEVYSQP-----PHMLSPQGSLMGPPPQQNLM 1469 Query: 1396 IPPQMRPRGMAADVGMGGFSQGPGNPGNMMF 1426 + +R R ++ D M G+ PG N+ F Sbjct: 1470 VSHPLRQRSVSLDSQM-GYLPAPGGMANLPF 1499 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 129 bits (324), Expect = 2e-29 Identities = 329/1225 (26%), Positives = 411/1225 (33%), Gaps = 261/1225 (21%) Query: 256 PTPPIPAPAPKPAAPPRPLDRESPGVENKLIPSVGSPASSTPLPPDGTGPNSTPNNRAVT 315 P PP A P P P +R G E G P S P PP G P Sbjct: 385 PGPPGAAVMGPPGPPGFPGERGQKGDE-------GPPGISIPGPPGLDGQPGAPGLPG-P 436 Query: 316 PVSQGSNSSSADPKAPPPPPVSSGEPPTLGENPDGLSQEQLEHRERSLQTLRDIQRMLFP 375 P G + +D P PP G P GL EQ ++ I Sbjct: 437 PGPAGPHIPPSDEICEPGPPGPPGSP-----GDKGLQGEQGVKGDKGDTCFNCI------ 485 Query: 376 DEKEFTGAQSGGPQQNPGVLDGPQKKPEGPIQAMMAQSQSLGKGPGPRTDVGAPFGPQGH 435 G GP PG+ P GP ++ Q KG T GP+G Sbjct: 486 ------GTGISGPPGQPGLPGLP-----GPPGSLGFPGQKGEKGQAGAT------GPKGL 528 Query: 436 RDVPFSP-------------DEMVPPSMNSQSGTIGPDHLDHM-----TPEQIAWLKLQQ 477 +P +P D + P M G +G + TP Q L Sbjct: 529 PGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPG 588 Query: 478 EFYEEK--RRKQEQVVVQQCSLQDMM--VHQHGPRGVVRGPPPPYQMTPSEGWAPGGTEP 533 E K E+ L + + GP G GPP P +G A +P Sbjct: 589 PKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF--GPPGPVGEKGIQGVAGNPGQP 646 Query: 534 FSDGINMPHSLPPRGMAPHPNMPGSQMRLPGFAGMINSEMEGPNVPNPASRPGLSGVSWP 593 GI P P + + P PG LPG G + ++ P P +PGL G+ Sbjct: 647 ---GIPGPKGDPGQTIT-QPGKPG----LPGNPGR-DGDVGLPGDPGLPGQPGLPGIPGS 697 Query: 594 DDVPKIPD-GRNFPPGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGI 652 P IP G PPG F G P P G G P + +EG Sbjct: 698 KGEPGIPGIGLPGPPGPKGFPG------IPGPPGAP-------------GTPGRIGLEGP 738 Query: 653 R--PSMEMNRMIPGSQRHMEPGNNPIFPRIP-VEGPLSPSRGDFPKGIPPQMGPGRELEF 709 P + PG PG P +P +G L P +GD +G P GP Sbjct: 739 PGPPGFPGPKGEPGFALPGPPGP----PGLPGFKGALGP-KGD--RGFPGPPGPPGRTGL 791 Query: 710 GMVPSGMKGDVNLNVNMGSNSQMIPQKMREAGAGPEEMLKLRPGGSDMLPAQQKMVPLPF 769 +P G KGDV G N Q P GP + PG P +P P Sbjct: 792 DGLP-GPKGDV------GPNGQPGPM-------GPPGL----PGIGVQGPPGPPGIPGPI 833 Query: 770 GEH-----PQQEYGMGPRPFLPMSQGPGSNS--GLRNLREPIGPDQRTNSRLSHMPPLPL 822 G+ P ++ GP P L + PG G+ PIGP P LP Sbjct: 834 GQPGLHGIPGEKGDPGP-PGLDVPGPPGERGSPGIPGAPGPIGPPGS--------PGLPG 884 Query: 823 NPSSNPTSLNTAPPVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGN 882 ++ G P + + G G+ LK Q Q P L P+G Sbjct: 885 KAGASGFPGTKGEMGMMGPPGPPGPLGIPGRS----GVPGLKGDDGLQGQ-PGLPGPTGE 939 Query: 883 LKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQ 942 S P L GP P +LGS P LP PG S PK Sbjct: 940 KGSKGEPG-----LPGPPGPMD---PNLLGSKGEKG----EPGLPG-IPG-VSGPKGYQG 985 Query: 943 SPGIPPNHKAPLTMASPAMLGNVESGGPPPPTAS-----QPASVNIPGSLPSSTPYTMPP 997 PG P P + G GPP P + QP + PG L + P Sbjct: 986 LPGDP---------GQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPG-LKGTIGDMGFP 1035 Query: 998 EPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARS----PNLPSMNNM 1053 P + P PS P + D P S P LP Sbjct: 1036 GPQGVEGPPG-----------PSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGE 1084 Query: 1054 PGMGINTQNPRISGP--NPVVPMPTLSPMGMTQPLSHSNQMPS-PNAVGPNIPP--HGVP 1108 PG+ NP I G +P +P +P QP +P P GP P G P Sbjct: 1085 PGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQP-----GLPGFPGTPGPPGPKGISGPP 1139 Query: 1109 MGPGLMSHNPIMGHGSQEPPMVPQGRMGFP--QGFPPVQSPPQQVPFPHNGPSGGQGSFP 1166 PGL +G G P G G P G P GP+G +G P Sbjct: 1140 GNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIP--------------GPAGQKGE-P 1184 Query: 1167 GGMGFPGEGPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRP 1226 G GF GP G P L D L PG PG P +P +P P Sbjct: 1185 GQPGFGNPGPPGLP-GLSGQKGDGGL--PGIPGNP--------GLPGPKGEPGFHGF--P 1231 Query: 1227 GATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGP--GPGFSHMQGMMGEQAPRM 1284 G G P P P L+ P+G PG PQGP PG + QG+ G + P Sbjct: 1232 GVQGPPG-------PPGSPGPALE-GPKGN-PG---PQGPPGRPGPTGFQGLPGPEGPP- 1278 Query: 1285 GLALPGMGG-PGPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMSPAQSTMPG 1343 LPG GG G G P P P +PG + P L QG G P + M G Sbjct: 1279 --GLPGNGGIKGEKGNPGQP--GLPGLPGLKGDQGPPGL-QGNPG------RPGLNGMKG 1327 Query: 1344 QPTLMSNPAAAVGMIPGKDRGPAGLYTHPGPVGSPGMM--MSMQGMMGPQ-QNIMIPPQM 1400 P L P PG +GP+G+ GP G PG++ G+ GP Q+I+I Sbjct: 1328 DPGLPGVPG-----FPGM-KGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDA 1381 Query: 1401 RPRGMAADVGMGGF--SQGP-GNPG 1422 P G+ G+ G QGP G PG Sbjct: 1382 GPPGIPGQPGLKGLPGPQGPQGLPG 1406 Score = 115 bits (288), Expect = 3e-25 Identities = 261/987 (26%), Positives = 330/987 (33%), Gaps = 208/987 (21%) Query: 506 GPRGVVRGPP--PPYQMTPSEGWAPGGTEPFSDGINMPHSLP-------PRGMAPHPNMP 556 GP+G+ RGPP P + TP PG DG P +P RG P P Sbjct: 87 GPKGI-RGPPGLPGFPGTPGLPGMPG-----HDGAPGPQGIPGCNGTKGERGFPGSPGFP 140 Query: 557 GSQ-----MRLPGFAG----MINSEMEGPNV-PNPASRPGLSGVSWPDDVPKIPDGRNFP 606 G Q +PG G +I S + GP P PG+ G+ P +P G P Sbjct: 141 GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIP----GPIGP 196 Query: 607 PGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEK-QLGL-----PPGMAMEGIRP-SMEMN 659 PG GP P P+G FQ EK + GL PPG E RP +E Sbjct: 197 PGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQ 256 Query: 660 RMIPGSQRHMEPGNNPIFPRIPVEGPLSPSRGDF----PKGIPPQMG-PGRELEFGM--V 712 + G P P + GP P G+ +G P + G PG++ E G + Sbjct: 257 KGDQGLPGDRGPPGPP-----GIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGI 311 Query: 713 PSGMKGDVNLNVNMGSNSQMIPQKMREAGAGPEEMLKLRPG-----------GSDMLPAQ 761 P G+ GD G + + QK GP ++ RPG G LP + Sbjct: 312 P-GLPGDPGYPGEPGRDGEK-GQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE 369 Query: 762 QKMVPLPFGEHPQQEYG------MGPR--PFLPMSQGPGSNSGLRNLREPIGP--DQRTN 811 + P + P G MGP P P +G + G + P P D + Sbjct: 370 KGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPG 429 Query: 812 SRLSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQV 871 + PP P P P+ P G P D + G Q G+ K T Sbjct: 430 APGLPGPPGPAGPHIPPSD-EICEPGPPGPPGSPGDKGLQGEQ----GVKGDKGDTCFNC 484 Query: 872 QSPMLGSPSGNLKSPQTPSQLAGM-------LAGPAAAASIKSPPVLGSAAASPVHLKSP 924 + P G P P + G A A K P + A +P S Sbjct: 485 IGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSK 544 Query: 925 SLPAPS---PGWTSSPKPPLQSPGIPPNHKAPLTMASPAMLGNVESGGPPPPTASQPASV 981 P PG K L SPG P P + G G P P Sbjct: 545 GEPGDILTFPGMKGD-KGELGSPGAP---------GLPGLPGTPGQDGLP----GLPGPK 590 Query: 982 NIPGSLPSSTPYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPP 1041 PG + P P L P +I F P P+ I+ VA + Sbjct: 591 GEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG--PVGEKGIQGVAGNPGQ--- 645 Query: 1042 ARSPNLPSMNNMPGMGINTQN-PRISGPNPVVPMPTLSPMGMTQPLSHSNQMPSPNAVG- 1099 P +P PG I P + G NP + P G Sbjct: 646 ---PGIPGPKGDPGQTITQPGKPGLPG-NP----------------GRDGDVGLPGDPGL 685 Query: 1100 PNIPPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPS 1159 P P G+P PG I G G PP P+GFP + PP P G Sbjct: 686 PGQP--GLPGIPGSKGEPGIPGIGLPGPPG--------PKGFPGIPGPPGAPGTP--GRI 733 Query: 1160 GGQGSFPGGMGFPGEGPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPD 1219 G +G PG GFPG P G P A PG PG P LG F P Sbjct: 734 GLEGP-PGPPGFPG--PKGEPGF-------ALPGPPGPPGLPGFKGALGPKGDRGFPGPP 783 Query: 1220 LQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPGPGFSHMQGMMGE 1279 PG TG+ +PG K GP G+ Sbjct: 784 GP----PGRTGLDG-----------------------LPGPKGDVGPN----------GQ 806 Query: 1280 QAPRMGLALPGMGGPGPVGTPDI--PLGT--APSMPGHNPMRPPAFLQQGMMGPHHRMMS 1335 P LPG+G GP G P I P+G +PG P L + GP S Sbjct: 807 PGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLD--VPGPPGERGS 864 Query: 1336 PAQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGLYTHPGPVGSPGMMMSMQGMMGPQQNIM 1395 P +PG P + P + +PGK AG PG G GMM G GP + Sbjct: 865 PG---IPGAPGPIGPPGSP--GLPGK----AGASGFPGTKGEMGMM----GPPGPPGPLG 911 Query: 1396 IPPQMRPRGMAADVGMGGFSQGPGNPG 1422 IP + G+ D G+ G PG PG Sbjct: 912 IPGRSGVPGLKGDDGLQG---QPGLPG 935 Score = 78.6 bits (192), Expect = 4e-14 Identities = 135/476 (28%), Positives = 174/476 (36%), Gaps = 112/476 (23%) Query: 1041 PARSPNLPSMNNMPGMGINTQNPRISGPNPVVPMPTLSPMGMTQPLSHSNQMPSPNAVGP 1100 P P +P M PG I + P G NP P P G+ Q L +P P +GP Sbjct: 145 PPGPPGIPGMKGEPGSIIMSSLPGPKG-NPGYP----GPPGI-QGLPGPTGIPGP--IGP 196 Query: 1101 NIPPH--GVPMGPGLMSHNPIMG------------HGSQEPPMVP--------------- 1131 PP G P PGL MG G Q PP P Sbjct: 197 PGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQ 256 Query: 1132 QGRMGFP-----QGFPPVQSPPQQVPFPHNGPSGGQGSFPGGMGFPG-EGPLGRPSNLPQ 1185 +G G P G P ++ PP P G G QG PG G PG +G G+P +P Sbjct: 257 KGDQGLPGDRGPPGPPGIRGPPGP-PGGEKGEKGEQGE-PGKRGKPGKDGENGQPG-IPG 313 Query: 1186 SSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGATGIPEFDLSRI----IP 1241 D PG PG P G + P + RPG TGI + I +P Sbjct: 314 LPGD-----PGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPG-TGITIGEKGNIGLPGLP 367 Query: 1242 SEKPSQTLQYFPRGE-VPGRKQPQG------PGP-GFSHMQGMMGEQAPRMGLALPGMGG 1293 EK + FP + PG P G PGP GF +G G++ P G+++PG G Sbjct: 368 GEKGERG---FPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPP-GISIPGPPG 423 Query: 1294 ----PGPVGTPDIPLGTAPSMPGHN------PMRPPAFL-------QQGMMGPH----HR 1332 PG G P P P +P + P PP +QG+ G Sbjct: 424 LDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFN 483 Query: 1333 MMSPAQSTMPGQPTL--MSNPAAAVGMIPGKD--------RGPAGLYT---------HPG 1373 + S PGQP L + P ++G PG+ GP GL PG Sbjct: 484 CIGTGISGPPGQPGLPGLPGPPGSLGF-PGQKGEKGQAGATGPKGLPGIPGAPGAPGFPG 542 Query: 1374 PVGSPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGP---GNPGNMMF 1426 G PG +++ GM G + + P G+ G G P G PG + F Sbjct: 543 SKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITF 598 Score = 64.7 bits (156), Expect = 6e-10 Identities = 100/329 (30%), Positives = 119/329 (36%), Gaps = 73/329 (22%) Query: 1111 PGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPSGGQGSFPGGMG 1170 PGL H + G E P P+G+ G G P PP P GP G G FPG G Sbjct: 53 PGLEGHPGLPGFPGPEGPPGPRGQKG-DDGIP---GPPG--PKGIRGPPGLPG-FPGTPG 105 Query: 1171 FPG-EGPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGAT 1229 PG G G P + + G PG P P LQ PG Sbjct: 106 LPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGF--------------PGLQGP--PGPP 149 Query: 1230 GIPEF--DLSRIIPSEKPSQTLQYFPRGEVPGRKQPQG----PGPGFSHMQGMMGEQAPR 1283 GIP + II S P P+G PG P G PGP + + G +G P Sbjct: 150 GIPGMKGEPGSIIMSSLPG------PKGN-PGYPGPPGIQGLPGP--TGIPGPIGPPGP- 199 Query: 1284 MGLALPG-MGGPGPVGTPDIPLGTAPSMPGHNPMRPPAFL-QQGMMGPHHRMMSPAQSTM 1341 PG MG PGP G P P G G N P +QG+ GP Sbjct: 200 -----PGLMGPPGPPGLPG-PKGNM----GLNFQGPKGEKGEQGLQGP------------ 237 Query: 1342 PGQPTLMSNPAAAVGM--------IPGKDRGPAGLYTHPGPVGSPGMMMSMQGMMGPQQN 1393 PG P +S + + +PG DRGP G GP G PG +G G Sbjct: 238 PGPPGQISEQKRPIDVEFQKGDQGLPG-DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGK 296 Query: 1394 IMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 P + G G+ G PG PG Sbjct: 297 RGKPGKDGENGQPGIPGLPGDPGYPGEPG 325 Score = 63.9 bits (154), Expect = 1e-09 Identities = 167/707 (23%), Positives = 233/707 (32%), Gaps = 156/707 (22%) Query: 235 PQQPPAPANQDQNSSQNTRLQPTPP-IPAPAPKPAAPPRPLDRESPGVENKLIP------ 287 P P P + P PP IP P +P P ++ PG +P Sbjct: 803 PNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGER 862 Query: 288 -SVGSPASSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPP--PVSSGEPPTL 344 S G P + P+ P G+ + P ++G P P P P SG P Sbjct: 863 GSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLK 922 Query: 345 GENPDGLSQEQL---EHRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPGV-----LD 396 G+ DGL + E+ + + P + G++ G + PG+ + Sbjct: 923 GD--DGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSK--GEKGEPGLPGIPGVS 978 Query: 397 GP---QKKPEGPIQAMMAQSQSLGKGPGPRTDVGAPFGPQGHRDVPFSPDEMVPPSMNSQ 453 GP Q P P Q ++ L PGP GP+G+ +P P + PP + Sbjct: 979 GPKGYQGLPGDPGQPGLSGQPGL---PGPP-------GPKGNPGLPGQPGLIGPPGL--- 1025 Query: 454 SGTIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRG 513 GTIG D P GP+G V G Sbjct: 1026 KGTIG----DMGFP--------------------------------------GPQG-VEG 1042 Query: 514 PPPPYQMTPSEGWAPG-------GTEPFSDGINMPHSLPPRGMAPHPNMPGS-------- 558 PP P P + +PG +P I +P P+G P PG+ Sbjct: 1043 PPGP-SGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVG 1101 Query: 559 QMRLPGFAGMINSEMEG--PNVPNPASRPGLSGVSWPDDVPKIP-----------DGRNF 605 LPG G ++ + P P PG G+S P P +P G+ Sbjct: 1102 DPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPG 1161 Query: 606 PPGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEK-QLGLP--PGMAMEGIRPSMEMNRMI 662 PPG+ G + P P G E Q GLP G +G P + N + Sbjct: 1162 PPGE---KGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGL 1218 Query: 663 PGSQRHMEPGNNPIFPRIP-VEGPLSPSRG-----DFPKGIP-PQMGPGRELEFGMV--- 712 PG P P F P V+GP P + PKG P PQ PGR G Sbjct: 1219 PG------PKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLP 1272 Query: 713 ----PSGMKGDVNLNVNMGSNSQM----IPQKMREAGAGPEEMLKLRPGGSDM------- 757 P G+ G+ + G+ Q +P + G + RPG + M Sbjct: 1273 GPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLP 1332 Query: 758 ----LPAQQKMVPLPFGEHPQQEYGMGPRPFLPMSQGPGSNSGLRNLREPIGPDQRTNSR 813 P + +P P+ E G+ P P GP S + ++ GP Sbjct: 1333 GVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSII--IKGDAGPPGIPGQP 1390 Query: 814 LSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLDISVAGSQVHSPGI 860 P P P P T PP G P AG + PG+ Sbjct: 1391 GLKGLPGPQGPQGLPGP--TGPPGDPGRNGLP-GFDGAGGRKGDPGL 1434 Score = 59.3 bits (142), Expect = 3e-08 Identities = 197/811 (24%), Positives = 258/811 (31%), Gaps = 135/811 (16%) Query: 231 PKPLPQQPPAPANQDQNSSQNTRLQPTPP-IPAPAPKP--AAPPRPLDRESPGVENKLIP 287 PK P P P P PP P P +P A P P PG + L P Sbjct: 714 PKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGP 773 Query: 288 SVGSPASSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGEPPTLGEN 347 P PP TG + P + G N P P + PP Sbjct: 774 KGDRGFPGPPGPPGRTGLDGLPGPKG----DVGPNGQPGPMGPPGLPGIGVQGPPGPPGI 829 Query: 348 PDGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQS------GGPQQNPGVLDGPQKK 401 P + Q L P EK G G + +PG+ P Sbjct: 830 PGPIGQPGLHG---------------IPGEKGDPGPPGLDVPGPPGERGSPGIPGAP--G 872 Query: 402 PEGPIQAMMAQSQSLGKG-PGPRTDVG--APFGPQGHRDVPFSPDEMVPPSMNSQSGTIG 458 P GP + ++ G PG + ++G P GP G + P P + G G Sbjct: 873 PIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGI---PGRSGVPGLKGDDGLQG 929 Query: 459 PDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQD-MMVHQHGPRGVVRGPPPP 517 L T EK K E + D ++ G +G P P Sbjct: 930 QPGLPGPT--------------GEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIP 975 Query: 518 YQMTPSEGWAPGGTEPFSDGINMPHSLP-PRGMAPHPNMPGSQMRL--PGFAGMINSEME 574 P +G+ +P G++ LP P G +P +PG + PG G I +M Sbjct: 976 GVSGP-KGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTI-GDMG 1033 Query: 575 GPNVPNPASRPGLSGVSWPDDVPKIP--DGRNFPPGQGIFSGPG----RGE----RFPNP 624 P PG SGV P +P G PG PG +GE +P Sbjct: 1034 FPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGN 1093 Query: 625 QGLSEEMFQQQLAEKQLGLP--PGMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIFPRIPV 682 G+ + L GLP PG + P PG + P NP P P Sbjct: 1094 PGIKGSVGDPGLP----GLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEP- 1148 Query: 683 EGPLSPSRGDFPKGIPPQMG-PGRELEFGMVPSGMKGDVNLNVNMGSNSQMIPQKMREAG 741 GP+ G P + G PG++ G P+G KG+ +P + G Sbjct: 1149 -GPVGGGGHPGQPGPPGEKGKPGQDGIPG--PAGQKGEPGQPGFGNPGPPGLPGLSGQKG 1205 Query: 742 AGPEEMLKLRPG--------GSDMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPMSQGPGS 793 G + PG G P Q P P E GP+ P QGP Sbjct: 1206 DGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALE---GPKG-NPGPQGPPG 1261 Query: 794 N---SGLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLDISV 850 +G + L P GP P LP N N P GL D Sbjct: 1262 RPGPTGFQGLPGPEGP-----------PGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGP 1310 Query: 851 AGSQVH--SPGINPLK-SPTMHQVQS-PMLGSPSG-----------NLKSPQTPSQLAG- 894 G Q + PG+N +K P + V P + PSG L P P L G Sbjct: 1311 PGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGP 1370 Query: 895 -----MLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPN 949 ++ G A I P L L P P PG T P P ++ G+P Sbjct: 1371 SGQSIIIKGDAGPPGIPGQPGLKG-------LPGPQGPQGLPGPTGPPGDPGRN-GLPGF 1422 Query: 950 HKAPLTMASPAMLGNVES---GGPPPPTASQ 977 A P + G + GPP P Q Sbjct: 1423 DGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQ 1453 Score = 37.7 bits (86), Expect = 0.080 Identities = 31/92 (33%), Positives = 38/92 (41%), Gaps = 16/92 (17%) Query: 1343 GQPTLMSNPAAAVGMIPGK------------DRGPAGLYTHPGPVGSPGMMMSMQGMMGP 1390 GQP + AA G PG +RG GL HPG G PG G G Sbjct: 21 GQP---AEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPG-PEGPPGPRGQ 76 Query: 1391 QQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 + + IP P+G+ G+ GF PG PG Sbjct: 77 KGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPG 108 Score = 33.5 bits (75), Expect = 1.5 Identities = 29/98 (29%), Positives = 36/98 (36%), Gaps = 16/98 (16%) Query: 36 PSGNPQLDSKFSNQGKQG--GSASQSQPSPCDSKSGGHTPKALPGPGGSMGLKNGAGNGA 93 P GNP QG G G P G P LPGP G+MGL G Sbjct: 169 PKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGE 228 Query: 94 KGK-------------GKRERSISADSFDQRDPGTPND 118 KG+ +++R I + F + D G P D Sbjct: 229 KGEQGLQGPPGPPGQISEQKRPIDVE-FQKGDQGLPGD 265 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 127 bits (319), Expect = 8e-29 Identities = 327/1245 (26%), Positives = 408/1245 (32%), Gaps = 250/1245 (20%) Query: 256 PTPPIPAPAPKPAAPPRPLDRESPGVENKLIPSVGSPASSTPLPPDGTGPNSTPNNRAVT 315 P PP A P P P +R G E G P S P PP G P Sbjct: 385 PGPPGAAVMGPPGPPGFPGERGQKGDE-------GPPGISIPGPPGLDGQPGAPGLPG-P 436 Query: 316 PVSQGSNSSSADPKAPPPPPVSSGEPPTLGENPDGLSQEQLEHRERSLQTLRDIQRMLFP 375 P G + +D P PP G P GL EQ ++ I Sbjct: 437 PGPAGPHIPPSDEICEPGPPGPPGSP-----GDKGLQGEQGVKGDKGDTCFNCI------ 485 Query: 376 DEKEFTGAQSGGPQQNPGVLDGPQKKPEGPIQAMMAQSQSLGKGPGPRTDVGAPFGPQGH 435 G GP PG+ P GP ++ Q KG T GP+G Sbjct: 486 ------GTGISGPPGQPGLPGLP-----GPPGSLGFPGQKGEKGQAGAT------GPKGL 528 Query: 436 RDVPFSP-------------DEMVPPSMNSQSGTIGPDHLDHM-----TPEQIAWLKLQQ 477 +P +P D + P M G +G + TP Q L Sbjct: 529 PGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPG 588 Query: 478 EFYEEK--RRKQEQVVVQQCSLQDMM--VHQHGPRGVVRGPPPPYQMTPSEGWAPGGTEP 533 E K E+ L + + GP G GPP P +G A +P Sbjct: 589 PKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF--GPPGPVGEKGIQGVAGNPGQP 646 Query: 534 FSDGINMPHSLPPRGMAPHPNMPGSQMRLPGFAGMINSEMEGPNVPNPASRPGLSGVSWP 593 GI P P + + P PG LPG G + ++ P P +PGL G+ Sbjct: 647 ---GIPGPKGDPGQTIT-QPGKPG----LPGNPGR-DGDVGLPGDPGLPGQPGLPGIPGS 697 Query: 594 DDVPKIPD-GRNFPPGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGI 652 P IP G PPG F G P P G G P + +EG Sbjct: 698 KGEPGIPGIGLPGPPGPKGFPG------IPGPPGAP-------------GTPGRIGLEGP 738 Query: 653 R--PSMEMNRMIPGSQRHMEPGNNPIFPRIP-VEGPLSPSRGDFPKGIPPQMGPGRELEF 709 P + PG PG P +P +G L P +GD +G P GP Sbjct: 739 PGPPGFPGPKGEPGFALPGPPGP----PGLPGFKGALGP-KGD--RGFPGPPGPPGRTGL 791 Query: 710 GMVPSGMKGDVNLNVNMGSNSQMIPQKMREAGAGPEEMLKLRPGGSDMLPAQQKMVPLPF 769 +P G KGDV G N Q P GP + PG P +P P Sbjct: 792 DGLP-GPKGDV------GPNGQPGPM-------GPPGL----PGIGVQGPPGPPGIPGPI 833 Query: 770 GEH-----PQQEYGMGPRPFLPMSQGPGSNS--GLRNLREPIGPDQRTNSRLSHMPPLPL 822 G+ P ++ GP P L + PG G+ PIGP P LP Sbjct: 834 GQPGLHGIPGEKGDPGP-PGLDVPGPPGERGSPGIPGAPGPIGPPGS--------PGLPG 884 Query: 823 NPSSNPTSLNTAPPVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGN 882 ++ G P + + G G+ LK Q Q P L P+G Sbjct: 885 KAGASGFPGTKGEMGMMGPPGPPGPLGIPGRS----GVPGLKGDDGLQGQ-PGLPGPTGE 939 Query: 883 LKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQ 942 S P L GP P +LGS P LP PG S PK Sbjct: 940 KGSKGEPG-----LPGPPGPMD---PNLLGSKGEKG----EPGLPG-IPG-VSGPKGYQG 985 Query: 943 SPGIPPNHKAPLTMASPAMLGNVESGGPPPPTAS-----QPASVNIPGSLPSSTPYTMPP 997 PG P P + G GPP P + QP + PG L + P Sbjct: 986 LPGDP---------GQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPG-LKGTIGDMGFP 1035 Query: 998 EPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARS----PNLPSMNNM 1053 P + P PS P + D P S P LP Sbjct: 1036 GPQGVEGPPG-----------PSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGE 1084 Query: 1054 PGMGINTQNPRISGP--NPVVPMPTLSPMGMTQPLSHSNQMPS-PNAVGPNIPP--HGVP 1108 PG+ NP I G +P +P +P QP +P P GP P G P Sbjct: 1085 PGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQP-----GLPGFPGTPGPPGPKGISGPP 1139 Query: 1109 MGPGLMSHNPIMGHGSQEPPMVPQGRMGFP--QGFPPV---QSPPQQVPFPHNGPSG--- 1160 PGL +G G P G G P G P + P Q F + GP G Sbjct: 1140 GNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPG 1199 Query: 1161 -----GQGSFPGGMGFPG-EGPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSV 1214 G G PG G PG GP G P PG PG P GN P Sbjct: 1200 LSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG-PALEGPKGNPGPQG 1258 Query: 1215 FTD-PDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGP-----GP 1268 P Q + PG G P + I EK + P +PG K QGP P Sbjct: 1259 PPGRPGFQGL--PGPEGPPGLPGNGGIKGEKGNPGQPGLPG--LPGLKGDQGPPGLQGNP 1314 Query: 1269 GFSHMQGMMGEQAPRMGLALPGMGGP-------GPVGTPDI--PLGTAPSMPGHNPMRPP 1319 G + GM G+ PGM GP GP G P + P G P +PG + Sbjct: 1315 GRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP-PGLPGPSGQ--- 1370 Query: 1320 AFLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGLYTHPGPVGSPG 1379 + + +G GP +PGQP L P +GP GL GP G PG Sbjct: 1371 SIIIKGDAGP---------PGIPGQPGLKGLPGP---------QGPQGLPGPTGPPGDPG 1412 Query: 1380 M--MMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 + G G + + +P Q RG+ G G PG PG Sbjct: 1413 RNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1457 Score = 120 bits (300), Expect = 1e-26 Identities = 318/1316 (24%), Positives = 417/1316 (31%), Gaps = 205/1316 (15%) Query: 231 PKPLPQQPPAPANQDQNSSQNTRLQPTPPIPAPAPKPAAPPR-PLDRESPGVENKLIPSV 289 PK P P P Q PP P P PP P + + G+ N P Sbjct: 169 PKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGL-NFQGPKG 227 Query: 290 GSPASSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGEP-PTLGENP 348 PP G S +G D + PP PP G P P GE Sbjct: 228 EKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGD-RGPPGPPGIRGPPGPPGGEK- 285 Query: 349 DGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPGVLDGPQKKPEGPIQA 408 G EQ E +R K ++G P PG+ P E Sbjct: 286 -GEKGEQGEPGKRG---------------KPGKDGENGQPGI-PGLPGDPGYPGEPGRDG 328 Query: 409 MMAQSQSLGKG--PG---PRTDVGAPFGPQGHRDVPFSPDEMVP---PSMNSQSGTIGPD 460 Q G PG PR G G +G+ +P P E P + G GP Sbjct: 329 EKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPP 388 Query: 461 HLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPPPPYQM 520 M P F E+ +K ++ GP G+ PP Sbjct: 389 GAAVMGPPG------PPGFPGERGQKGDE----------------GPPGISIPGPPGLDG 426 Query: 521 TPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPG-----SQMRLPGFAGMINSEMEG 575 P PG P I + G P PG + + G G G Sbjct: 427 QPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIG 486 Query: 576 PNVPNPASRPGLSGVSWPDDVPKIPD--------GRNFPPG-QGIFSGPGRGERFPNPQG 626 + P +PGL G+ P P G P G GI PG FP +G Sbjct: 487 TGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPG-APGFPGSKG 545 Query: 627 LSEEM--FQQQLAEK-QLGLPPGMAMEGI--RPSMEMNRMIPGSQRHMEPGNNPIFPRIP 681 ++ F +K +LG P + G+ P + +PG + EPG I Sbjct: 546 EPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKG--EPGG------IT 597 Query: 682 VEGPLSPSRGDFPKGIPPQMGPGRELEFGMVPSGMKGDVNLNVNMGSNSQM-IPQKMREA 740 +G P G+P +GP FG P G G+ + G+ Q IP + Sbjct: 598 FKGERGPPGNPGLPGLPGNIGPMGPPGFG--PPGPVGEKGIQGVAGNPGQPGIPGPKGDP 655 Query: 741 GAGPEEM----LKLRPG--------GSDMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPMS 788 G + L PG G LP Q + +P + G+G LP Sbjct: 656 GQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIG----LPGP 711 Query: 789 QGPGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLDI 848 GP G+ G R PP P P PP GL + Sbjct: 712 PGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGAL 771 Query: 849 SVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGM-LAGPAAAASIKS 907 G + P + + P P P L G+ + GP I Sbjct: 772 GPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPG 831 Query: 908 P---PVLGSAAASPVHLKSPSLPAP-------SPGWTSSPKP--PLQSPGIPPNHKAPLT 955 P P L P L P SPG +P P P SPG+P A Sbjct: 832 PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGF 891 Query: 956 MASPAMLGNVESGGPPPPTASQPASVNIPG-----------SLPSST-PYTMPPEPTLSQ 1003 + +G + GPP P P +PG LP T EP L Sbjct: 892 PGTKGEMGMMGPPGPPGPLGI-PGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPG 950 Query: 1004 NPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGM---GINT 1060 P + + + L I V+ P P ++ PG+ Sbjct: 951 PPGPMDPNLLGSKGEKGEPGL--PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPK 1008 Query: 1061 QNPRISGPNPVVPMPTL----------SPMGMTQPLSHSNQMPSPNAVG----------P 1100 NP + G ++ P L P G+ P S P + G P Sbjct: 1009 GNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDP 1068 Query: 1101 NIPPHGVPMGPGLMSHNPIMGH-------GSQEPPMVP--------QGRMGFPQGFPPVQ 1145 I G+P PG + G+ GS P +P +G+ G P GFP Sbjct: 1069 GISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLP-GFPGTP 1127 Query: 1146 SPPQQVPFPHNGPSGGQGSFPGGMGFPGE-GPLGRPSNLPQSSADAALCKPGGPGGPDSF 1204 PP GP G G PG G PGE GP+G + Q KPG G P Sbjct: 1128 GPP--------GPKGISGP-PGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPA 1178 Query: 1205 TVLGNSMPSVFTDPDLQEVI----RPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGR 1260 G F +P + + G G+P + +P K FP + P Sbjct: 1179 GQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGP-P 1237 Query: 1261 KQPQGPGPGFSHMQGMMGEQAPRMGLALPGMGG-PGPVGTPDIPLGTA-------PSMPG 1312 P PGP +G G Q P PG G PGP G P +P P PG Sbjct: 1238 GPPGSPGPALEGPKGNPGPQGPP---GRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPG 1294 Query: 1313 HNPMRPPAFLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGLYTHP 1372 P P QG G P + M G P L P PG +GP+G+ Sbjct: 1295 -LPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPG-----FPGM-KGPSGVPGSA 1347 Query: 1373 GPVGSPGMM--MSMQGMMGPQ-QNIMIPPQMRPRGMAADVGMGGF--SQGP-GNPG 1422 GP G PG++ G+ GP Q+I+I P G+ G+ G QGP G PG Sbjct: 1348 GPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPG 1403 Score = 115 bits (288), Expect = 3e-25 Identities = 261/987 (26%), Positives = 330/987 (33%), Gaps = 208/987 (21%) Query: 506 GPRGVVRGPP--PPYQMTPSEGWAPGGTEPFSDGINMPHSLP-------PRGMAPHPNMP 556 GP+G+ RGPP P + TP PG DG P +P RG P P Sbjct: 87 GPKGI-RGPPGLPGFPGTPGLPGMPG-----HDGAPGPQGIPGCNGTKGERGFPGSPGFP 140 Query: 557 GSQ-----MRLPGFAG----MINSEMEGPNV-PNPASRPGLSGVSWPDDVPKIPDGRNFP 606 G Q +PG G +I S + GP P PG+ G+ P +P G P Sbjct: 141 GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIP----GPIGP 196 Query: 607 PGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEK-QLGL-----PPGMAMEGIRP-SMEMN 659 PG GP P P+G FQ EK + GL PPG E RP +E Sbjct: 197 PGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQ 256 Query: 660 RMIPGSQRHMEPGNNPIFPRIPVEGPLSPSRGDF----PKGIPPQMG-PGRELEFGM--V 712 + G P P + GP P G+ +G P + G PG++ E G + Sbjct: 257 KGDQGLPGDRGPPGPP-----GIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGI 311 Query: 713 PSGMKGDVNLNVNMGSNSQMIPQKMREAGAGPEEMLKLRPG-----------GSDMLPAQ 761 P G+ GD G + + QK GP ++ RPG G LP + Sbjct: 312 P-GLPGDPGYPGEPGRDGEK-GQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE 369 Query: 762 QKMVPLPFGEHPQQEYG------MGPR--PFLPMSQGPGSNSGLRNLREPIGP--DQRTN 811 + P + P G MGP P P +G + G + P P D + Sbjct: 370 KGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPG 429 Query: 812 SRLSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQV 871 + PP P P P+ P G P D + G Q G+ K T Sbjct: 430 APGLPGPPGPAGPHIPPSD-EICEPGPPGPPGSPGDKGLQGEQ----GVKGDKGDTCFNC 484 Query: 872 QSPMLGSPSGNLKSPQTPSQLAGM-------LAGPAAAASIKSPPVLGSAAASPVHLKSP 924 + P G P P + G A A K P + A +P S Sbjct: 485 IGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSK 544 Query: 925 SLPAPS---PGWTSSPKPPLQSPGIPPNHKAPLTMASPAMLGNVESGGPPPPTASQPASV 981 P PG K L SPG P P + G G P P Sbjct: 545 GEPGDILTFPGMKGD-KGELGSPGAP---------GLPGLPGTPGQDGLP----GLPGPK 590 Query: 982 NIPGSLPSSTPYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPP 1041 PG + P P L P +I F P P+ I+ VA + Sbjct: 591 GEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG--PVGEKGIQGVAGNPGQ--- 645 Query: 1042 ARSPNLPSMNNMPGMGINTQN-PRISGPNPVVPMPTLSPMGMTQPLSHSNQMPSPNAVG- 1099 P +P PG I P + G NP + P G Sbjct: 646 ---PGIPGPKGDPGQTITQPGKPGLPG-NP----------------GRDGDVGLPGDPGL 685 Query: 1100 PNIPPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPS 1159 P P G+P PG I G G PP P+GFP + PP P G Sbjct: 686 PGQP--GLPGIPGSKGEPGIPGIGLPGPPG--------PKGFPGIPGPPGAPGTP--GRI 733 Query: 1160 GGQGSFPGGMGFPGEGPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPD 1219 G +G PG GFPG P G P A PG PG P LG F P Sbjct: 734 GLEGP-PGPPGFPG--PKGEPGF-------ALPGPPGPPGLPGFKGALGPKGDRGFPGPP 783 Query: 1220 LQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPGPGFSHMQGMMGE 1279 PG TG+ +PG K GP G+ Sbjct: 784 GP----PGRTGLDG-----------------------LPGPKGDVGPN----------GQ 806 Query: 1280 QAPRMGLALPGMGGPGPVGTPDI--PLGT--APSMPGHNPMRPPAFLQQGMMGPHHRMMS 1335 P LPG+G GP G P I P+G +PG P L + GP S Sbjct: 807 PGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLD--VPGPPGERGS 864 Query: 1336 PAQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGLYTHPGPVGSPGMMMSMQGMMGPQQNIM 1395 P +PG P + P + +PGK AG PG G GMM G GP + Sbjct: 865 PG---IPGAPGPIGPPGSP--GLPGK----AGASGFPGTKGEMGMM----GPPGPPGPLG 911 Query: 1396 IPPQMRPRGMAADVGMGGFSQGPGNPG 1422 IP + G+ D G+ G PG PG Sbjct: 912 IPGRSGVPGLKGDDGLQG---QPGLPG 935 Score = 78.6 bits (192), Expect = 4e-14 Identities = 135/476 (28%), Positives = 174/476 (36%), Gaps = 112/476 (23%) Query: 1041 PARSPNLPSMNNMPGMGINTQNPRISGPNPVVPMPTLSPMGMTQPLSHSNQMPSPNAVGP 1100 P P +P M PG I + P G NP P P G+ Q L +P P +GP Sbjct: 145 PPGPPGIPGMKGEPGSIIMSSLPGPKG-NPGYP----GPPGI-QGLPGPTGIPGP--IGP 196 Query: 1101 NIPPH--GVPMGPGLMSHNPIMG------------HGSQEPPMVP--------------- 1131 PP G P PGL MG G Q PP P Sbjct: 197 PGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQ 256 Query: 1132 QGRMGFP-----QGFPPVQSPPQQVPFPHNGPSGGQGSFPGGMGFPG-EGPLGRPSNLPQ 1185 +G G P G P ++ PP P G G QG PG G PG +G G+P +P Sbjct: 257 KGDQGLPGDRGPPGPPGIRGPPGP-PGGEKGEKGEQGE-PGKRGKPGKDGENGQPG-IPG 313 Query: 1186 SSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGATGIPEFDLSRI----IP 1241 D PG PG P G + P + RPG TGI + I +P Sbjct: 314 LPGD-----PGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPG-TGITIGEKGNIGLPGLP 367 Query: 1242 SEKPSQTLQYFPRGE-VPGRKQPQG------PGP-GFSHMQGMMGEQAPRMGLALPGMGG 1293 EK + FP + PG P G PGP GF +G G++ P G+++PG G Sbjct: 368 GEKGERG---FPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPP-GISIPGPPG 423 Query: 1294 ----PGPVGTPDIPLGTAPSMPGHN------PMRPPAFL-------QQGMMGPH----HR 1332 PG G P P P +P + P PP +QG+ G Sbjct: 424 LDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFN 483 Query: 1333 MMSPAQSTMPGQPTL--MSNPAAAVGMIPGKD--------RGPAGLYT---------HPG 1373 + S PGQP L + P ++G PG+ GP GL PG Sbjct: 484 CIGTGISGPPGQPGLPGLPGPPGSLGF-PGQKGEKGQAGATGPKGLPGIPGAPGAPGFPG 542 Query: 1374 PVGSPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGP---GNPGNMMF 1426 G PG +++ GM G + + P G+ G G P G PG + F Sbjct: 543 SKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITF 598 Score = 64.7 bits (156), Expect = 6e-10 Identities = 100/329 (30%), Positives = 119/329 (36%), Gaps = 73/329 (22%) Query: 1111 PGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPSGGQGSFPGGMG 1170 PGL H + G E P P+G+ G G P PP P GP G G FPG G Sbjct: 53 PGLEGHPGLPGFPGPEGPPGPRGQKG-DDGIP---GPPG--PKGIRGPPGLPG-FPGTPG 105 Query: 1171 FPG-EGPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGAT 1229 PG G G P + + G PG P P LQ PG Sbjct: 106 LPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGF--------------PGLQGP--PGPP 149 Query: 1230 GIPEF--DLSRIIPSEKPSQTLQYFPRGEVPGRKQPQG----PGPGFSHMQGMMGEQAPR 1283 GIP + II S P P+G PG P G PGP + + G +G P Sbjct: 150 GIPGMKGEPGSIIMSSLPG------PKGN-PGYPGPPGIQGLPGP--TGIPGPIGPPGP- 199 Query: 1284 MGLALPG-MGGPGPVGTPDIPLGTAPSMPGHNPMRPPAFL-QQGMMGPHHRMMSPAQSTM 1341 PG MG PGP G P P G G N P +QG+ GP Sbjct: 200 -----PGLMGPPGPPGLPG-PKGNM----GLNFQGPKGEKGEQGLQGP------------ 237 Query: 1342 PGQPTLMSNPAAAVGM--------IPGKDRGPAGLYTHPGPVGSPGMMMSMQGMMGPQQN 1393 PG P +S + + +PG DRGP G GP G PG +G G Sbjct: 238 PGPPGQISEQKRPIDVEFQKGDQGLPG-DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGK 296 Query: 1394 IMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 P + G G+ G PG PG Sbjct: 297 RGKPGKDGENGQPGIPGLPGDPGYPGEPG 325 Score = 37.7 bits (86), Expect = 0.080 Identities = 31/92 (33%), Positives = 38/92 (41%), Gaps = 16/92 (17%) Query: 1343 GQPTLMSNPAAAVGMIPGK------------DRGPAGLYTHPGPVGSPGMMMSMQGMMGP 1390 GQP + AA G PG +RG GL HPG G PG G G Sbjct: 21 GQP---AEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPG-PEGPPGPRGQ 76 Query: 1391 QQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 + + IP P+G+ G+ GF PG PG Sbjct: 77 KGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPG 108 Score = 33.5 bits (75), Expect = 1.5 Identities = 29/98 (29%), Positives = 36/98 (36%), Gaps = 16/98 (16%) Query: 36 PSGNPQLDSKFSNQGKQG--GSASQSQPSPCDSKSGGHTPKALPGPGGSMGLKNGAGNGA 93 P GNP QG G G P G P LPGP G+MGL G Sbjct: 169 PKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGE 228 Query: 94 KGK-------------GKRERSISADSFDQRDPGTPND 118 KG+ +++R I + F + D G P D Sbjct: 229 KGEQGLQGPPGPPGQISEQKRPIDVE-FQKGDQGLPGD 265 >gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sapiens] Length = 1685 Score = 126 bits (317), Expect = 1e-28 Identities = 326/1244 (26%), Positives = 408/1244 (32%), Gaps = 251/1244 (20%) Query: 256 PTPPIPAPAPKPAAPPRPLDRESPGVENKLIPSVGSPASSTPLPPDGTGPNSTPNNRAVT 315 P PP A P P P +R G E G P S P PP G P Sbjct: 385 PGPPGAAVMGPPGPPGFPGERGQKGDE-------GPPGISIPGPPGLDGQPGAPGLPG-P 436 Query: 316 PVSQGSNSSSADPKAPPPPPVSSGEPPTLGENPDGLSQEQLEHRERSLQTLRDIQRMLFP 375 P G + +D P PP G P GL EQ ++ I Sbjct: 437 PGPAGPHIPPSDEICEPGPPGPPGSP-----GDKGLQGEQGVKGDKGDTCFNCI------ 485 Query: 376 DEKEFTGAQSGGPQQNPGVLDGPQKKPEGPIQAMMAQSQSLGKGPGPRTDVGAPFGPQGH 435 G GP PG+ P GP ++ Q KG T GP+G Sbjct: 486 ------GTGISGPPGQPGLPGLP-----GPPGSLGFPGQKGEKGQAGAT------GPKGL 528 Query: 436 RDVPFSP-------------DEMVPPSMNSQSGTIGPDHLDHM-----TPEQIAWLKLQQ 477 +P +P D + P M G +G + TP Q L Sbjct: 529 PGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPG 588 Query: 478 EFYEEK--RRKQEQVVVQQCSLQDMM--VHQHGPRGVVRGPPPPYQMTPSEGWAPGGTEP 533 E K E+ L + + GP G GPP P +G A +P Sbjct: 589 PKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGF--GPPGPVGEKGIQGVAGNPGQP 646 Query: 534 FSDGINMPHSLPPRGMAPHPNMPGSQMRLPGFAGMINSEMEGPNVPNPASRPGLSGVSWP 593 GI P P + + P PG LPG G + ++ P P +PGL G+ Sbjct: 647 ---GIPGPKGDPGQTIT-QPGKPG----LPGNPGR-DGDVGLPGDPGLPGQPGLPGIPGS 697 Query: 594 DDVPKIPD-GRNFPPGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGI 652 P IP G PPG F G P P G G P + +EG Sbjct: 698 KGEPGIPGIGLPGPPGPKGFPG------IPGPPGAP-------------GTPGRIGLEGP 738 Query: 653 R--PSMEMNRMIPGSQRHMEPGNNPIFPRIP-VEGPLSPSRGDFPKGIPPQMGPGRELEF 709 P + PG PG P +P +G L P +GD +G P GP Sbjct: 739 PGPPGFPGPKGEPGFALPGPPGP----PGLPGFKGALGP-KGD--RGFPGPPGPPGRTGL 791 Query: 710 GMVPSGMKGDVNLNVNMGSNSQMIPQKMREAGAGPEEMLKLRPGGSDMLPAQQKMVPLPF 769 +P G KGDV G N Q P GP + PG P +P P Sbjct: 792 DGLP-GPKGDV------GPNGQPGPM-------GPPGL----PGIGVQGPPGPPGIPGPI 833 Query: 770 GEH-----PQQEYGMGPRPFLPMSQGPGSNS--GLRNLREPIGPDQRTNSRLSHMPPLPL 822 G+ P ++ GP P L + PG G+ PIGP P LP Sbjct: 834 GQPGLHGIPGEKGDPGP-PGLDVPGPPGERGSPGIPGAPGPIGPPGS--------PGLPG 884 Query: 823 NPSSNPTSLNTAPPVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGN 882 ++ G P + + G G+ LK Q Q P L P+G Sbjct: 885 KAGASGFPGTKGEMGMMGPPGPPGPLGIPGRS----GVPGLKGDDGLQGQ-PGLPGPTGE 939 Query: 883 LKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQ 942 S P L GP P +LGS P LP PG S PK Sbjct: 940 KGSKGEPG-----LPGPPGPMD---PNLLGSKGEKG----EPGLPG-IPG-VSGPKGYQG 985 Query: 943 SPGIPPNHKAPLTMASPAMLGNVESGGPPPPTAS-----QPASVNIPGSLPSSTPYTMPP 997 PG P P + G GPP P + QP + PG L + P Sbjct: 986 LPGDP---------GQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPG-LKGTIGDMGFP 1035 Query: 998 EPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARS----PNLPSMNNM 1053 P + P PS P + D P S P LP Sbjct: 1036 GPQGVEGPPG-----------PSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGE 1084 Query: 1054 PGMGINTQNPRISGP--NPVVPMPTLSPMGMTQPLSHSNQMPS-PNAVGPNIPP--HGVP 1108 PG+ NP I G +P +P +P QP +P P GP P G P Sbjct: 1085 PGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQP-----GLPGFPGTPGPPGPKGISGPP 1139 Query: 1109 MGPGLMSHNPIMGHGSQEPPMVPQGRMGFP--QGFPPV---QSPPQQVPFPHNGPSG--- 1160 PGL +G G P G G P G P + P Q F + GP G Sbjct: 1140 GNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPG 1199 Query: 1161 -----GQGSFPGGMGFPG-EGPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSV 1214 G G PG G PG GP G P PG PG P GN P Sbjct: 1200 LSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG-PALEGPKGNPGPQ- 1257 Query: 1215 FTDPDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGP-----GPG 1269 P + + PG G P + I EK + P +PG K QGP PG Sbjct: 1258 --GPPGRPGL-PGPEGPPGLPGNGGIKGEKGNPGQPGLPG--LPGLKGDQGPPGLQGNPG 1312 Query: 1270 FSHMQGMMGEQAPRMGLALPGMGGP-------GPVGTPDI--PLGTAPSMPGHNPMRPPA 1320 + GM G+ PGM GP GP G P + P G P +PG + + Sbjct: 1313 RPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGP-PGLPGPSGQ---S 1368 Query: 1321 FLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGLYTHPGPVGSPGM 1380 + +G GP +PGQP L P +GP GL GP G PG Sbjct: 1369 IIIKGDAGP---------PGIPGQPGLKGLPGP---------QGPQGLPGPTGPPGDPGR 1410 Query: 1381 --MMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 + G G + + +P Q RG+ G G PG PG Sbjct: 1411 NGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1454 Score = 120 bits (300), Expect = 1e-26 Identities = 318/1316 (24%), Positives = 417/1316 (31%), Gaps = 208/1316 (15%) Query: 231 PKPLPQQPPAPANQDQNSSQNTRLQPTPPIPAPAPKPAAPPR-PLDRESPGVENKLIPSV 289 PK P P P Q PP P P PP P + + G+ N P Sbjct: 169 PKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGL-NFQGPKG 227 Query: 290 GSPASSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGEP-PTLGENP 348 PP G S +G D + PP PP G P P GE Sbjct: 228 EKGEQGLQGPPGPPGQISEQKRPIDVEFQKGDQGLPGD-RGPPGPPGIRGPPGPPGGEK- 285 Query: 349 DGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPGVLDGPQKKPEGPIQA 408 G EQ E +R K ++G P PG+ P E Sbjct: 286 -GEKGEQGEPGKRG---------------KPGKDGENGQPGI-PGLPGDPGYPGEPGRDG 328 Query: 409 MMAQSQSLGKG--PG---PRTDVGAPFGPQGHRDVPFSPDEMVP---PSMNSQSGTIGPD 460 Q G PG PR G G +G+ +P P E P + G GP Sbjct: 329 EKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPP 388 Query: 461 HLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPPPPYQM 520 M P F E+ +K ++ GP G+ PP Sbjct: 389 GAAVMGPPG------PPGFPGERGQKGDE----------------GPPGISIPGPPGLDG 426 Query: 521 TPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPG-----SQMRLPGFAGMINSEMEG 575 P PG P I + G P PG + + G G G Sbjct: 427 QPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIG 486 Query: 576 PNVPNPASRPGLSGVSWPDDVPKIPD--------GRNFPPG-QGIFSGPGRGERFPNPQG 626 + P +PGL G+ P P G P G GI PG FP +G Sbjct: 487 TGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPG-APGFPGSKG 545 Query: 627 LSEEM--FQQQLAEK-QLGLPPGMAMEGI--RPSMEMNRMIPGSQRHMEPGNNPIFPRIP 681 ++ F +K +LG P + G+ P + +PG + EPG I Sbjct: 546 EPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKG--EPGG------IT 597 Query: 682 VEGPLSPSRGDFPKGIPPQMGPGRELEFGMVPSGMKGDVNLNVNMGSNSQM-IPQKMREA 740 +G P G+P +GP FG P G G+ + G+ Q IP + Sbjct: 598 FKGERGPPGNPGLPGLPGNIGPMGPPGFG--PPGPVGEKGIQGVAGNPGQPGIPGPKGDP 655 Query: 741 GAGPEEM----LKLRPG--------GSDMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPMS 788 G + L PG G LP Q + +P + G+G LP Sbjct: 656 GQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIG----LPGP 711 Query: 789 QGPGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLDI 848 GP G+ G R PP P P PP GL + Sbjct: 712 PGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGAL 771 Query: 849 SVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGM-LAGPAAAASIKS 907 G + P + + P P P L G+ + GP I Sbjct: 772 GPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPG 831 Query: 908 P---PVLGSAAASPVHLKSPSLPAP-------SPGWTSSPKP--PLQSPGIPPNHKAPLT 955 P P L P L P SPG +P P P SPG+P A Sbjct: 832 PIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGF 891 Query: 956 MASPAMLGNVESGGPPPPTASQPASVNIPG-----------SLPSST-PYTMPPEPTLSQ 1003 + +G + GPP P P +PG LP T EP L Sbjct: 892 PGTKGEMGMMGPPGPPGPLGI-PGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPG 950 Query: 1004 NPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGM---GINT 1060 P + + + L I V+ P P ++ PG+ Sbjct: 951 PPGPMDPNLLGSKGEKGEPGL--PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPK 1008 Query: 1061 QNPRISGPNPVVPMPTL----------SPMGMTQPLSHSNQMPSPNAVG----------P 1100 NP + G ++ P L P G+ P S P + G P Sbjct: 1009 GNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDP 1068 Query: 1101 NIPPHGVPMGPGLMSHNPIMGH-------GSQEPPMVP--------QGRMGFPQGFPPVQ 1145 I G+P PG + G+ GS P +P +G+ G P GFP Sbjct: 1069 GISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLP-GFPGTP 1127 Query: 1146 SPPQQVPFPHNGPSGGQGSFPGGMGFPGE-GPLGRPSNLPQSSADAALCKPGGPGGPDSF 1204 PP GP G G PG G PGE GP+G + Q KPG G P Sbjct: 1128 GPP--------GPKGISGP-PGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPA 1178 Query: 1205 TVLGNSMPSVFTDPDLQEVI----RPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGR 1260 G F +P + + G G+P + +P K FP + P Sbjct: 1179 GQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGP-P 1237 Query: 1261 KQPQGPGPGFSHMQGMMGEQAPRMGLALPGMGG-PGPVGTPDIPLGTA-------PSMPG 1312 P PGP +G G Q P PG G PGP G P +P P PG Sbjct: 1238 GPPGSPGPALEGPKGNPGPQGP------PGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPG 1291 Query: 1313 HNPMRPPAFLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGLYTHP 1372 P P QG G P + M G P L P PG +GP+G+ Sbjct: 1292 -LPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPG-----FPGM-KGPSGVPGSA 1344 Query: 1373 GPVGSPGMM--MSMQGMMGPQ-QNIMIPPQMRPRGMAADVGMGGF--SQGP-GNPG 1422 GP G PG++ G+ GP Q+I+I P G+ G+ G QGP G PG Sbjct: 1345 GPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPG 1400 Score = 115 bits (288), Expect = 3e-25 Identities = 261/987 (26%), Positives = 330/987 (33%), Gaps = 208/987 (21%) Query: 506 GPRGVVRGPP--PPYQMTPSEGWAPGGTEPFSDGINMPHSLP-------PRGMAPHPNMP 556 GP+G+ RGPP P + TP PG DG P +P RG P P Sbjct: 87 GPKGI-RGPPGLPGFPGTPGLPGMPG-----HDGAPGPQGIPGCNGTKGERGFPGSPGFP 140 Query: 557 GSQ-----MRLPGFAG----MINSEMEGPNV-PNPASRPGLSGVSWPDDVPKIPDGRNFP 606 G Q +PG G +I S + GP P PG+ G+ P +P G P Sbjct: 141 GLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIP----GPIGP 196 Query: 607 PGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEK-QLGL-----PPGMAMEGIRP-SMEMN 659 PG GP P P+G FQ EK + GL PPG E RP +E Sbjct: 197 PGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQ 256 Query: 660 RMIPGSQRHMEPGNNPIFPRIPVEGPLSPSRGDF----PKGIPPQMG-PGRELEFGM--V 712 + G P P + GP P G+ +G P + G PG++ E G + Sbjct: 257 KGDQGLPGDRGPPGPP-----GIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGI 311 Query: 713 PSGMKGDVNLNVNMGSNSQMIPQKMREAGAGPEEMLKLRPG-----------GSDMLPAQ 761 P G+ GD G + + QK GP ++ RPG G LP + Sbjct: 312 P-GLPGDPGYPGEPGRDGEK-GQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE 369 Query: 762 QKMVPLPFGEHPQQEYG------MGPR--PFLPMSQGPGSNSGLRNLREPIGP--DQRTN 811 + P + P G MGP P P +G + G + P P D + Sbjct: 370 KGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPG 429 Query: 812 SRLSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQV 871 + PP P P P+ P G P D + G Q G+ K T Sbjct: 430 APGLPGPPGPAGPHIPPSD-EICEPGPPGPPGSPGDKGLQGEQ----GVKGDKGDTCFNC 484 Query: 872 QSPMLGSPSGNLKSPQTPSQLAGM-------LAGPAAAASIKSPPVLGSAAASPVHLKSP 924 + P G P P + G A A K P + A +P S Sbjct: 485 IGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSK 544 Query: 925 SLPAPS---PGWTSSPKPPLQSPGIPPNHKAPLTMASPAMLGNVESGGPPPPTASQPASV 981 P PG K L SPG P P + G G P P Sbjct: 545 GEPGDILTFPGMKGD-KGELGSPGAP---------GLPGLPGTPGQDGLP----GLPGPK 590 Query: 982 NIPGSLPSSTPYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPP 1041 PG + P P L P +I F P P+ I+ VA + Sbjct: 591 GEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPG--PVGEKGIQGVAGNPGQ--- 645 Query: 1042 ARSPNLPSMNNMPGMGINTQN-PRISGPNPVVPMPTLSPMGMTQPLSHSNQMPSPNAVG- 1099 P +P PG I P + G NP + P G Sbjct: 646 ---PGIPGPKGDPGQTITQPGKPGLPG-NP----------------GRDGDVGLPGDPGL 685 Query: 1100 PNIPPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPS 1159 P P G+P PG I G G PP P+GFP + PP P G Sbjct: 686 PGQP--GLPGIPGSKGEPGIPGIGLPGPPG--------PKGFPGIPGPPGAPGTP--GRI 733 Query: 1160 GGQGSFPGGMGFPGEGPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPD 1219 G +G PG GFPG P G P A PG PG P LG F P Sbjct: 734 GLEGP-PGPPGFPG--PKGEPGF-------ALPGPPGPPGLPGFKGALGPKGDRGFPGPP 783 Query: 1220 LQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPGPGFSHMQGMMGE 1279 PG TG+ +PG K GP G+ Sbjct: 784 GP----PGRTGLDG-----------------------LPGPKGDVGPN----------GQ 806 Query: 1280 QAPRMGLALPGMGGPGPVGTPDI--PLGT--APSMPGHNPMRPPAFLQQGMMGPHHRMMS 1335 P LPG+G GP G P I P+G +PG P L + GP S Sbjct: 807 PGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLD--VPGPPGERGS 864 Query: 1336 PAQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGLYTHPGPVGSPGMMMSMQGMMGPQQNIM 1395 P +PG P + P + +PGK AG PG G GMM G GP + Sbjct: 865 PG---IPGAPGPIGPPGSP--GLPGK----AGASGFPGTKGEMGMM----GPPGPPGPLG 911 Query: 1396 IPPQMRPRGMAADVGMGGFSQGPGNPG 1422 IP + G+ D G+ G PG PG Sbjct: 912 IPGRSGVPGLKGDDGLQG---QPGLPG 935 Score = 78.6 bits (192), Expect = 4e-14 Identities = 135/476 (28%), Positives = 174/476 (36%), Gaps = 112/476 (23%) Query: 1041 PARSPNLPSMNNMPGMGINTQNPRISGPNPVVPMPTLSPMGMTQPLSHSNQMPSPNAVGP 1100 P P +P M PG I + P G NP P P G+ Q L +P P +GP Sbjct: 145 PPGPPGIPGMKGEPGSIIMSSLPGPKG-NPGYP----GPPGI-QGLPGPTGIPGP--IGP 196 Query: 1101 NIPPH--GVPMGPGLMSHNPIMG------------HGSQEPPMVP--------------- 1131 PP G P PGL MG G Q PP P Sbjct: 197 PGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQ 256 Query: 1132 QGRMGFP-----QGFPPVQSPPQQVPFPHNGPSGGQGSFPGGMGFPG-EGPLGRPSNLPQ 1185 +G G P G P ++ PP P G G QG PG G PG +G G+P +P Sbjct: 257 KGDQGLPGDRGPPGPPGIRGPPGP-PGGEKGEKGEQGE-PGKRGKPGKDGENGQPG-IPG 313 Query: 1186 SSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGATGIPEFDLSRI----IP 1241 D PG PG P G + P + RPG TGI + I +P Sbjct: 314 LPGD-----PGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPG-TGITIGEKGNIGLPGLP 367 Query: 1242 SEKPSQTLQYFPRGE-VPGRKQPQG------PGP-GFSHMQGMMGEQAPRMGLALPGMGG 1293 EK + FP + PG P G PGP GF +G G++ P G+++PG G Sbjct: 368 GEKGERG---FPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPP-GISIPGPPG 423 Query: 1294 ----PGPVGTPDIPLGTAPSMPGHN------PMRPPAFL-------QQGMMGPH----HR 1332 PG G P P P +P + P PP +QG+ G Sbjct: 424 LDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFN 483 Query: 1333 MMSPAQSTMPGQPTL--MSNPAAAVGMIPGKD--------RGPAGLYT---------HPG 1373 + S PGQP L + P ++G PG+ GP GL PG Sbjct: 484 CIGTGISGPPGQPGLPGLPGPPGSLGF-PGQKGEKGQAGATGPKGLPGIPGAPGAPGFPG 542 Query: 1374 PVGSPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGP---GNPGNMMF 1426 G PG +++ GM G + + P G+ G G P G PG + F Sbjct: 543 SKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITF 598 Score = 64.7 bits (156), Expect = 6e-10 Identities = 100/329 (30%), Positives = 119/329 (36%), Gaps = 73/329 (22%) Query: 1111 PGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPSGGQGSFPGGMG 1170 PGL H + G E P P+G+ G G P PP P GP G G FPG G Sbjct: 53 PGLEGHPGLPGFPGPEGPPGPRGQKG-DDGIP---GPPG--PKGIRGPPGLPG-FPGTPG 105 Query: 1171 FPG-EGPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGAT 1229 PG G G P + + G PG P P LQ PG Sbjct: 106 LPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPGF--------------PGLQGP--PGPP 149 Query: 1230 GIPEF--DLSRIIPSEKPSQTLQYFPRGEVPGRKQPQG----PGPGFSHMQGMMGEQAPR 1283 GIP + II S P P+G PG P G PGP + + G +G P Sbjct: 150 GIPGMKGEPGSIIMSSLPG------PKGN-PGYPGPPGIQGLPGP--TGIPGPIGPPGP- 199 Query: 1284 MGLALPG-MGGPGPVGTPDIPLGTAPSMPGHNPMRPPAFL-QQGMMGPHHRMMSPAQSTM 1341 PG MG PGP G P P G G N P +QG+ GP Sbjct: 200 -----PGLMGPPGPPGLPG-PKGNM----GLNFQGPKGEKGEQGLQGP------------ 237 Query: 1342 PGQPTLMSNPAAAVGM--------IPGKDRGPAGLYTHPGPVGSPGMMMSMQGMMGPQQN 1393 PG P +S + + +PG DRGP G GP G PG +G G Sbjct: 238 PGPPGQISEQKRPIDVEFQKGDQGLPG-DRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGK 296 Query: 1394 IMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 P + G G+ G PG PG Sbjct: 297 RGKPGKDGENGQPGIPGLPGDPGYPGEPG 325 Score = 37.7 bits (86), Expect = 0.080 Identities = 31/92 (33%), Positives = 38/92 (41%), Gaps = 16/92 (17%) Query: 1343 GQPTLMSNPAAAVGMIPGK------------DRGPAGLYTHPGPVGSPGMMMSMQGMMGP 1390 GQP + AA G PG +RG GL HPG G PG G G Sbjct: 21 GQP---AEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPG-PEGPPGPRGQ 76 Query: 1391 QQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 + + IP P+G+ G+ GF PG PG Sbjct: 77 KGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPG 108 Score = 33.5 bits (75), Expect = 1.5 Identities = 29/98 (29%), Positives = 36/98 (36%), Gaps = 16/98 (16%) Query: 36 PSGNPQLDSKFSNQGKQG--GSASQSQPSPCDSKSGGHTPKALPGPGGSMGLKNGAGNGA 93 P GNP QG G G P G P LPGP G+MGL G Sbjct: 169 PKGNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGE 228 Query: 94 KGK-------------GKRERSISADSFDQRDPGTPND 118 KG+ +++R I + F + D G P D Sbjct: 229 KGEQGLQGPPGPPGQISEQKRPIDVE-FQKGDQGLPGD 265 >gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] Length = 1669 Score = 115 bits (289), Expect = 2e-25 Identities = 302/1238 (24%), Positives = 379/1238 (30%), Gaps = 268/1238 (21%) Query: 233 PLPQQPPAPANQDQNSSQNTRLQPTPPIPAPAPK---PAAPPRPLDRESPGVENKLIPSV 289 P+P Q AP + + R P +P P+ + P P P PG N ++ Sbjct: 376 PVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIV--- 432 Query: 290 GSPASSTPLPPDGTGPNSTPNNRAVTPV--SQGSNSSSA---------DPKAPPPPPVSS 338 P PP GP P +G S P P PP Sbjct: 433 ----ECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEI 488 Query: 339 GEPPTLGENPDGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPGVLDGP 398 G P G D R L P G GPQ PG++ P Sbjct: 489 GFPGQPGAKGD-----------RGL-----------PGRDGVAGVP--GPQGTPGLIGQP 524 Query: 399 QKKPEGPIQAMMAQSQSLGKG-------PGPRTDVGAPFGPQGHRDVPF---SPD----- 443 K E P + KG PG G+P G GH +P SP Sbjct: 525 GAKGE-PGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSP-GRDGHPGLPGPKGSPGSVGLK 582 Query: 444 -EMVPPS---MNSQSGTIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQD 499 E PP G GP P K Q F Sbjct: 583 GERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGP---------------- 626 Query: 500 MMVHQHGPRGVVRGPPPPYQMTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPGSQ 559 G G+ P ++ P G P G E P RG P PG Sbjct: 627 ------GSPGLPGPKGEPGKIVPLPG--PPGAEGLPGSPGFPGPQGDRGFPGTPGRPG-- 676 Query: 560 MRLPGFAGMINSEMEG-PNVPNPASRPGLSGVSWPDDVPKIPDGRNFPPGQGIFSGPGR- 617 LPG G + G P P P GL G P P P P G+ G Sbjct: 677 --LPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEP 734 Query: 618 GERFPNPQGLSE-EMFQQQLAEK-QLGLP--PGMAMEGIRPSMEMNRMIPGSQRHMEPGN 673 G P +GL EK +G+P PG P ++ R PG Sbjct: 735 GVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVG 794 Query: 674 NPIFPRIPVEGPLSPSRGDFPKGIPPQMGPGRELEF----GMVPSGMKGDVNLNVNMGSN 729 +P P I G P G P G+ G E F G+ G KGD Sbjct: 795 SPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGD--------KG 846 Query: 730 SQMIPQKMREAGAGPEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPMSQ 789 +Q +P ++G PG LP QQ +P + E G+ P P S Sbjct: 847 AQGLPGITGQSGL---------PG----LPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSP 893 Query: 790 GPGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLDIS 849 GP GL P ++ + H P P +P V GL KP Sbjct: 894 GPVGAPGL--------PGEKGD----HGFPGSSGPRGDPGLKGDKGDV--GLPGKP---- 935 Query: 850 VAGSQVHSPGINPLKSPTMHQVQSPMLG--SPSGNLKSPQTPSQLA--GMLAGPAAAASI 905 + + +K Q + +G G+ P TP G P Sbjct: 936 ---GSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPK 992 Query: 906 KSPPVLGSAAASPVHLKSPSLPAP--SPGWTSSPKPPLQS--PGIPPNHKAPLTMASPAM 961 P + G+ A P LP P S G P P + PGIP +P Sbjct: 993 GDPGISGTPGA-------PGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGA 1045 Query: 962 LGNVESGGPP----------------------PPTASQPASVNIPGSLPSSTPYTMPPEP 999 G GPP P + S+ IPG MP P Sbjct: 1046 KGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPG---------MPGSP 1096 Query: 1000 TLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMGIN 1059 L +P S+ P S L + LP ++ +PG+ Sbjct: 1097 GLKGSPGSV--------GYPGSPGLPGEK--------------GDKGLPGLDGIPGVKGE 1134 Query: 1060 TQNPRISGPNPVVPMPTLSPMGMT-QPLSHSNQMPSPNAVGPNIPPHGVPMGPGLMSHNP 1118 P GP P G +P S + P +P G P PG Sbjct: 1135 AGLPGTPGPT--------GPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKG 1186 Query: 1119 IMGH----GSQEPPMVP--QGRMGF-----PQGFPPVQSPPQQVPFPHNGPSGGQGSFPG 1167 G G P +P +G GF PQG P + P G G QG PG Sbjct: 1187 SKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQ-PG 1245 Query: 1168 GMGFPGEGPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPG 1227 G PG P+G P PG PG P +P DP Q + PG Sbjct: 1246 LPGLPG--PMGPPGLPGIDGVKGDKGNPGWPGAP--------GVPGPKGDPGFQGM--PG 1293 Query: 1228 ATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPGPGFSHMQGMMGEQAPRMGLA 1287 G P S+ P G VPG + P+G PG ++G G+Q Sbjct: 1294 IGGSPGITGSKG----------DMGPPG-VPGFQGPKGL-PGLQGIKGDQGDQGVPGAKG 1341 Query: 1288 LPGMGGPGPVGTPDIPLGTAPSMPGHNPMRPPAFLQ-QGMMGPHHRMMSPAQSTMPGQPT 1346 LPG PGP G DI G P +PG P PP QG+ GP + +PG P Sbjct: 1342 LPGP--PGPPGPYDIIKGE-PGLPG--PEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPG 1396 Query: 1347 LMS---NPAAAVGMIPGKDRGPAGLYTHPGPVGSPGMM 1381 + P M P GP G PGP G PG M Sbjct: 1397 IPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSM 1434 Score = 103 bits (256), Expect = 2e-21 Identities = 237/941 (25%), Positives = 302/941 (32%), Gaps = 159/941 (16%) Query: 546 PRGMAPHPNMPGSQMRLPGFAGMINSEMEGPNVPNPASRPGLSGVSWPDDVPKIPDGRNF 605 P G + +P PG LPG G +GP P P PG +G K G Sbjct: 95 PPGASGYPGNPG----LPGIPGQ-----DGP--PGPPGIPGCNGT-------KGERGPLG 136 Query: 606 PPGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGS 665 PPG F+G P +G E+ LG PGM ++G R PG Sbjct: 137 PPGLPGFAGNPGPPGLPGMKGDPGEI---------LGHVPGMLLKG-------ERGFPGI 180 Query: 666 QRHMEPGNNPIFPRIP-VEGPLSPSRGDFPKGIPPQMGP-GRELEFGMV---PSGMKGDV 720 PG P P +P ++GP+ P P G P GP G + + G+ P G KGD Sbjct: 181 -----PGT-PGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQ 234 Query: 721 NLNVNMGSNSQMIPQKMREAGAGPEEMLKLRPGGSDMLPAQQKMVPLPFGEH--PQQEYG 778 ++ G Q Q+ + E+ K PG M +K P G P ++ Sbjct: 235 GVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGD 294 Query: 779 MGPRPFLPMSQGPGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQ 838 G + P G GL + P G PP P P + Sbjct: 295 KGEKGS-PGFPGEPGYPGLIGRQGPQGEKGEAG------PPGP-------------PGIV 334 Query: 839 RGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGMLAG 898 G G PL +PG P P P G P P + G Sbjct: 335 IGTG--PLGEKGERGYPGTPG--PRGEP-----------GPKGFPGLPGQPGPPGLPVPG 379 Query: 899 PAAAASIKSPPVLGSAAASPVHLKSPSLPAPS-----PGWTSSPKPPLQ----------S 943 A A P SLP PS PG SP PP Q Sbjct: 380 QAGAPGFPGERGEKGDRGFP----GTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQ 435 Query: 944 PGIPPNHKAPLTMASPAMLGNVESGGP---------------PPPTASQPASVNIPGSLP 988 PG P + P P +G + G PP P + PG Sbjct: 436 PGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPG 495 Query: 989 SSTPYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLP 1048 + +P ++ P P + + + D P P P Sbjct: 496 AKGDRGLPGRDGVAGVPGP--QGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPG-FPGQP 552 Query: 1049 SMNNMPGMGINTQNPRISGPNPVVPMPTLS-----PMGMTQPLSHSNQ-MPSPNAVGPNI 1102 M G +P + GP L P G+ P S + P P GP Sbjct: 553 GMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAG 612 Query: 1103 P-----PHGVPMGPGLMSHNPIMGHGSQEPPMV-PQGRMGFPQGFPPVQSPPQQVPFPHN 1156 P G P GPG G + P+ P G G P G P P FP Sbjct: 613 PIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLP-GSPGFPGPQGDRGFPGT 671 Query: 1157 GPSGGQGSFPGGMGFPGEGPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFT 1216 G G +G PG G G P + PG PG P + GN P V Sbjct: 672 PGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGN--PGVQG 729 Query: 1217 DPDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPGPGFSHMQGM 1276 V PG G+P P EK S + VPG GP PG ++G Sbjct: 730 QKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVP-----GVPGEHGAIGP-PGLQGIRGE 783 Query: 1277 MGEQAPRMGLALPGMGGPGPVGTPDIPLGTAP----SMPGHNPMRP-PAFLQQGMMGPHH 1331 G + PG+ G GP G P G P PG + P F M GP Sbjct: 784 PGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKG 843 Query: 1332 RMMSPA------QSTMPGQPTLMSNPAAAVGMIPG--KDRGPAGLYTHPGPVGSPGMMMS 1383 + QS +PG P P IPG +G G+ PG GSPG + Sbjct: 844 DKGAQGLPGITGQSGLPGLPGQQGAPG-----IPGFPGSKGEMGVMGTPGQPGSPGPV-G 897 Query: 1384 MQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPGNM 1424 G+ G + + P PRG G G PG PG+M Sbjct: 898 APGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSM 938 Score = 102 bits (254), Expect = 3e-21 Identities = 319/1296 (24%), Positives = 414/1296 (31%), Gaps = 247/1296 (19%) Query: 235 PQQPPAPANQDQNSSQNTRLQPTPPIPAPAPKPAAPPRPLDRESPGVENKLIPSVGSPAS 294 P PP + + L P P +P A P P P + PG +P + Sbjct: 116 PPGPPGIPGCNGTKGERGPLGP-PGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGE 174 Query: 295 -STPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGEPPTLGENPDGLSQ 353 P P GP P + PV + P PP PP G+ + P G Sbjct: 175 RGFPGIPGTPGPPGLPGLQG--PVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKG 232 Query: 354 EQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPGVLDGPQKKPEGPIQAMMAQS 413 +Q + +Q ++ +F G + PG P +G Sbjct: 233 DQGVSGPPGVPGQAQVQ-----EKGDFATKGEKGQKGEPGFQGMPGVGEKG--------- 278 Query: 414 QSLGKGPGPRTDVGAPFGPQGHRDVPFSPDEMVPPSMNSQSGTIGPDHLDHMTPEQIAWL 473 GK PGPR G G +G + P P E P + + G G Sbjct: 279 -EPGK-PGPRGKPGKD-GDKGEKGSPGFPGEPGYPGLIGRQGPQG--------------- 320 Query: 474 KLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPPP-------PYQMTPSEGW 526 K E GP G+V G P Y TP Sbjct: 321 -----------EKGE-------------AGPPGPPGIVIGTGPLGEKGERGYPGTPGPRG 356 Query: 527 APGGTE-PFSDGINMPHSLPPRGMAPHPNMPGSQMRLPGFAGMINSEMEGPN----VPNP 581 PG P G P LP G A P PG + G G + + GP+ +P P Sbjct: 357 EPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGE-KGDRGFPGTSLPGPSGRDGLPGP 415 Query: 582 ASRPGLSGVSWPDDVPKIPDGRNFPPGQ----GIFSGPG----------RGERF------ 621 PG G P I + + PPG GI PG +GE Sbjct: 416 PGSPGPPGQ--PGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDID 473 Query: 622 -----PNPQGLSEEMF--QQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPGNN 674 P PQG E+ Q A+ GLP + G+ +I EPG Sbjct: 474 GYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEF 533 Query: 675 PIFPRIPVEGPLSPSRGDFPKGIPPQMG-------PGRELEFGMV-PSGMKGDVNLNVNM 726 R L +GD G P Q G PGR+ G+ P G G V L Sbjct: 534 YFDLR------LKGDKGD--PGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGER 585 Query: 727 GSNSQM-IPQKMREAG---------AGP--EEMLKLRPGG--SDMLPAQQ----KMVPLP 768 G + P + G AGP ++ PGG S LP + K+VPLP Sbjct: 586 GPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLP 645 Query: 769 FGEHPQQEYGMGPRPFLPMSQGPGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNPSS-- 826 P G+ P P QG G T R P LP + Sbjct: 646 ---GPPGAEGLPGSPGFPGPQGDRGFPG-------------TPGR----PGLPGEKGAVG 685 Query: 827 NPTSLNTAPPVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGNLKSP 886 P PP +G+ P D+ G+ PG N L Q Q G P L Sbjct: 686 QPGIGFPGPPGPKGVDGLPGDMGPPGTPGR-PGFNGLPGNPGVQGQK---GEPGVGLPGL 741 Query: 887 QTPSQLAGMLAGPAAAASIKSPPVLGS-AAASPVHLKS-PSLPAPS--PGWTSSPKPP-L 941 + L G+ P SI P V G A P L+ P P PG SP P + Sbjct: 742 KGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGI 801 Query: 942 QSPGI--PPNHKAPLTMASPAMLGNVESGGPPPPTASQPASVNIPGS--LPSSTPYTMPP 997 PG PP + P ++ P + E G P P P G+ LP T + P Sbjct: 802 GPPGARGPPGGQGPPGLSGPPGIKG-EKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLP 860 Query: 998 EPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSM---NNMP 1054 Q I SK M + P +P LP + P Sbjct: 861 GLPGQQGAPGIPGFPGSKGEM---------GVMGTPGQPGSPGPVGAPGLPGEKGDHGFP 911 Query: 1055 GMGINTQNPRISGPNPVVPMP----TLSPMGMTQPLSHSNQMPSPNAVGP--NIPPHGVP 1108 G +P + G V +P ++ + M +GP G P Sbjct: 912 GSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDP 971 Query: 1109 MGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPSGGQGSFPGG 1168 PG+ + G Q P G G P G P + P V GG Sbjct: 972 GTPGVPGKDGQAGQPGQPGPKGDPGISGTP-GAPGLPGPKGSV---------------GG 1015 Query: 1169 MGFPG----EGPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVI 1224 MG PG +G G P PQ S PG PG + G + P P L+ Sbjct: 1016 MGLPGTPGEKGVPGIPG--PQGS-------PGLPGDKGAKGEKGQAGPPGIGIPGLRG-- 1064 Query: 1225 RPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPGPGFSHMQGMMGEQAPRM 1284 G GI F S EK S + P PG K G G+ G+ GE+ + Sbjct: 1065 EKGDQGIAGFPGSPGEKGEKGSIGIPGMPGS--PGLKGSPG-SVGYPGSPGLPGEKGDK- 1120 Query: 1285 GLALPGMGG-PGPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMSPAQSTMPG 1343 LPG+ G PG G +P P+ P P + G G P + PG Sbjct: 1121 --GLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRG-FPG 1177 Query: 1344 QPTLMSNPAAA--VGM--------IPGKDRGPAGLYTHPGPVGSPGMMMSM-------QG 1386 P + + VG IPG +G G PGP G PG+ S +G Sbjct: 1178 FPGAKGDKGSKGEVGFPGLAGSPGIPGS-KGEQGFMGPPGPQGQPGLPGSPGHATEGPKG 1236 Query: 1387 MMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 GPQ +P P G G+ G GNPG Sbjct: 1237 DRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPG 1272 Score = 92.8 bits (229), Expect = 2e-18 Identities = 260/1044 (24%), Positives = 325/1044 (31%), Gaps = 210/1044 (20%) Query: 513 GPPPPYQMTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPGSQMRLPGFAG----- 567 GPP P + G G P P LP G A +P PG LPG G Sbjct: 115 GPPGPPGIPGCNG-TKGERGPLG-----PPGLP--GFAGNPGPPG----LPGMKGDPGEI 162 Query: 568 -------MINSEMEGPNVPN---PASRPGLSGVSWPDDV--PKIPDGRNFPPGQ----GI 611 ++ E P +P P PGL G P P P G PPG+ G+ Sbjct: 163 LGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGL 222 Query: 612 -FSGPGRGERFPNPQGLSEEMFQQQLAEK----------QLGLPPGMAMEGI----RPSM 656 F GP + G Q Q+ EK Q G P M G+ P Sbjct: 223 SFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGK 282 Query: 657 EMNRMIPGSQRHMEPGNNPIFPRIPVEGPLSPSRGDFPKGIPPQMGPGRE--LEFGMVPS 714 R PG +P FP P L +G P+G + GP + G P Sbjct: 283 PGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQG--PQGEKGEAGPPGPPGIVIGTGPL 340 Query: 715 GMKGDVNLNVNMGSNSQMIPQKMREAGAGPEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQ 774 G KG+ G E G L +PG + Q P GE + Sbjct: 341 GEKGERGYPGTPGPRG--------EPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGE 392 Query: 775 QEYGMGPRPFLPMSQGPGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTA 834 + P LP G G P G TN + P P P + Sbjct: 393 KGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPP--GDQGPPGIPGQ 450 Query: 835 PPVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGSPS-------------- 880 P +G K G I+ + P Q +G P Sbjct: 451 PGFIGEIGEK----GQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRD 506 Query: 881 --GNLKSPQTPSQLAGM---------------LAGPAAAASIKSPPVLGSAAASPVHLKS 923 + PQ L G L G P + A SP Sbjct: 507 GVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGH 566 Query: 924 PSLPAP-----------------------SPGWTSSPKPPLQSPGIPPNHKA----PLTM 956 P LP P S G T P PP P P K P Sbjct: 567 PGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGP 626 Query: 957 ASPAMLGNVESGGPPPPTASQPASVNIPGSLPSSTPYTMPPEPTLSQNPLSIMMSRMSKF 1016 SP + G G P P + +PGS P P P + Sbjct: 627 GSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRP--GLPGEKGAV 684 Query: 1017 AMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMGINTQNPRISGP--NPVVPM 1074 P K V D P +P P N +PG NP + G P V + Sbjct: 685 GQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPG------NPGVQGQKGEPGVGL 738 Query: 1075 PTLSPMGMTQPLSHSNQMPSPNAVG-PNIP-PHGVPMGPGLMSHNPIMGHGSQEPPMVPQ 1132 P L G+ ++G P +P HG PGL G PP +P Sbjct: 739 PGLK--GLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGI-----RGEPGPPGLP- 790 Query: 1133 GRMGFPQGFPPVQSPPQQVPFPHNGPSG--------GQGSFPG--GMGFPG----EGPLG 1178 G +G P G P + P + P GP G G+ FPG G+ PG +G G Sbjct: 791 GSVGSP-GVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQG 849 Query: 1179 RPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGATGIPEFDLSR 1238 P QS + G PG P F M + T PG G P + Sbjct: 850 LPGITGQSGLPGLPGQQGAPGIP-GFPGSKGEMGVMGT---------PGQPGSPGPVGAP 899 Query: 1239 IIPSEKPSQTL--QYFPRGEVPGRKQPQG----PG-PG------FSHMQGMMGEQAPRMG 1285 +P EK PRG+ PG K +G PG PG M+G G+Q + Sbjct: 900 GLPGEKGDHGFPGSSGPRGD-PGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQ 958 Query: 1286 LALPG-MGGPGPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMSPAQSTMPGQ 1344 + G G G GTP +P + Q G GP P S PG Sbjct: 959 IGPIGEKGSRGDPGTPGVPGKDGQAG------------QPGQPGPKG---DPGISGTPGA 1003 Query: 1345 PTLMSNPAAAVGM-IPGKDRGPAGLYTHPGPVGSPGM-----MMSMQGMMGPQQNIMIPP 1398 P L + GM +PG G G+ PGP GSPG+ +G GP I IP Sbjct: 1004 PGLPGPKGSVGGMGLPGTP-GEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGP-PGIGIPG 1061 Query: 1399 QMRPRGMAADVGMGGFSQGPGNPG 1422 RG D G+ GF PG G Sbjct: 1062 L---RGEKGDQGIAGFPGSPGEKG 1082 Score = 58.5 bits (140), Expect = 4e-08 Identities = 98/346 (28%), Positives = 122/346 (35%), Gaps = 83/346 (23%) Query: 1132 QGRMGFP--QGFPPVQSPPQQ--------VPFPHN--GPSGGQG--SFPGGMGFPG-EGP 1176 QG +GFP QG Q PP Q +P GP G G PG G PG +GP Sbjct: 57 QGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGP 116 Query: 1177 LGRPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGATGIPEFDL 1236 G P +P + P GP G F GN P P L PG G P L Sbjct: 117 PG-PPGIPGCNGTKGERGPLGPPGLPGFA--GNPGP-----PGL-----PGMKGDPGEIL 163 Query: 1237 SRI----IPSEKPSQTLQYFPRGE-VPGRKQPQGPGPGFSHMQGMMGEQAP-----RMGL 1286 + + E+ + P +PG + P GP PGF+ G G P +MGL Sbjct: 164 GHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGP-PGFTGPPGPPGPPGPPGEKGQMGL 222 Query: 1287 ALPG----MGGPGPVGTPDIPLGTA----------------------PSMPG----HNPM 1316 + G G G G P +P G A MPG P Sbjct: 223 SFQGPKGDKGDQGVSGPPGVP-GQAQVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPG 281 Query: 1317 RPPAFLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGLYTHPGPVG 1376 +P + G G SP PG P L+ +GP G GP G Sbjct: 282 KPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGR------------QGPQGEKGEAGPPG 329 Query: 1377 SPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 PG+++ G +G + P PRG G G PG PG Sbjct: 330 PPGIVIG-TGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPG 374 Score = 45.1 bits (105), Expect = 5e-04 Identities = 56/192 (29%), Positives = 72/192 (37%), Gaps = 49/192 (25%) Query: 1265 GPGPGFSHMQGMMGEQAPRMGL-------ALPGMGGP-GPVGTPDIPLGTA-PSMPGHNP 1315 G G G G+ G++ R GL PGM GP GP G P T P +PG Sbjct: 33 GSGCGKCDCHGVKGQKGER-GLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPG--- 88 Query: 1316 MRPPAFLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAAAVGMIPG-----KDRGPAG--- 1367 +G GP P +PG P P G IPG +RGP G Sbjct: 89 -------TKGTRGPPGASGYPGNPGLPGIPG-QDGPPGPPG-IPGCNGTKGERGPLGPPG 139 Query: 1368 ---LYTHPGPVGSPGMMMSMQGMMGPQQNIMI--------------PPQMRPRGMAADVG 1410 +PGP G PGM ++G +++ PP + G+ VG Sbjct: 140 LPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGL--PGLQGPVG 197 Query: 1411 MGGFSQGPGNPG 1422 GF+ PG PG Sbjct: 198 PPGFTGPPGPPG 209 Score = 44.7 bits (104), Expect = 7e-04 Identities = 148/641 (23%), Positives = 201/641 (31%), Gaps = 132/641 (20%) Query: 21 KSKQEVMVRP--PTVMSPSGNPQLDSKFSNQGKQGGSASQSQPSPCDSKSGGHTPKALPG 78 K + VM P P P G P L + + G G S + P G LPG Sbjct: 878 KGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPG----LKGDKGDVGLPG 933 Query: 79 PGGSMG-LKNGAGNGAKGKGKRERSIS--ADSFDQRDPGTPNDDSDIKECNSADHIKSQD 135 GSM + G+ G KG + I + + DPGTP + +D Sbjct: 934 KPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPG-------------VPGKD 980 Query: 136 SQHTPHSMTPSNATAPRSSTPSHGQTTATEPTPAQKTPAKVVYVFSTEMANKAAEAVLKG 195 Q S TP A P V + E + G Sbjct: 981 GQAGQPGQPGPKGDPGISGTPG-----------APGLPGPKGSVGGMGLPGTPGEKGVPG 1029 Query: 196 QVETIVSFHIQNISNNKTERSTA-PLNTQISALRNDP--KPLPQQPPAPANQDQNSSQNT 252 S + K E+ A P I LR + + + P +P + + S Sbjct: 1030 IPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGI 1089 Query: 253 RLQPTPPIPAPAP-------KPAAPPRPLDRESPGVENKLIPSVGSPAS--STPLPPDGT 303 P P +P P P D+ PG++ IP V A TP P Sbjct: 1090 PGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDG--IPGVKGEAGLPGTPGPTGPA 1147 Query: 304 GPNSTPNNRAVTPVSQGSNSSSADPKAP----PPPPVSSGEPPTLGE-NPDGLSQEQLEH 358 G P + + GS +P P P P + G+ + GE GL+ Sbjct: 1148 GQKGEPGSDGIP----GSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIP 1203 Query: 359 RERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPGVLDGPQKKPEGPIQAMMAQSQSLGK 418 + E+ F G GPQ PG+ P EGP Q Q Sbjct: 1204 GSKG--------------EQGFMGPP--GPQGQPGLPGSPGHATEGPKGDRGPQGQPGLP 1247 Query: 419 G-PGPRTDVGAPF-----GPQGHRDVPFSPDEMVP---------------PSMNSQSGTI 457 G PGP G P G +G+ P +P P P + G + Sbjct: 1248 GLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDM 1307 Query: 458 GPDHLDHMT-PEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPPP 516 GP + P+ + L+ K + +Q V L GP G PP Sbjct: 1308 GPPGVPGFQGPKGLPGLQ------GIKGDQGDQGVPGAKGLP-------GPPG----PPG 1350 Query: 517 PYQMTPSEGWAPGGTEPFSDGINMPHSLP-PR------GMAPHPNMPGSQMRLPGFAGMI 569 PY + E PG P G+ LP P+ G+ P PG +PGF G Sbjct: 1351 PYDIIKGEPGLPGPEGP--PGLKGLQGLPGPKGQQGVTGLVGIPGPPG----IPGFDGAP 1404 Query: 570 NSEME-GP-------NVPNPASRPGLSGVSWPDDVPKIPDG 602 + E GP P P GL G P P + G Sbjct: 1405 GQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTPSVDHG 1445 Score = 34.7 bits (78), Expect = 0.67 Identities = 34/124 (27%), Positives = 47/124 (37%), Gaps = 21/124 (16%) Query: 6 PKVRSSPSGNTQSSPKSKQEVMVRP-----PTVMSPSGNPQLDSKFSNQGKQGGSASQSQ 60 P + SP G+ PK + +P P M P G P +D ++G G + Sbjct: 1221 PGLPGSP-GHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGV 1279 Query: 61 PSPCDSKSGGHTPKALPGPGGSMGLKNGAGN----------GAKGKGKRERSISADSFDQ 110 P P G + +PG GGS G+ G+ G KG + I D DQ Sbjct: 1280 PGP----KGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQ-GIKGDQGDQ 1334 Query: 111 RDPG 114 PG Sbjct: 1335 GVPG 1338 >gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo sapiens] Length = 1424 Score = 113 bits (283), Expect = 1e-24 Identities = 249/963 (25%), Positives = 327/963 (33%), Gaps = 250/963 (25%) Query: 506 GPRGVVRGPPPPYQMTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPGSQMRLPGF 565 G +GV P PP + P + P G P G HP G PG Sbjct: 628 GTQGVPGAPGPPGEAGPRGELSVSTPVPGPPG--------PPGPPGHPGPQGP----PGI 675 Query: 566 AGMINSEMEGPNVPNPASRPGLSGVSWPDDVPKIPDG-RNFPPGQGIFSGPGR-GER-FP 622 G + + P +P P PG+ G+ +P P P G + FP +G PG+ GE P Sbjct: 676 PGSLG-KCGDPGLPGPDGEPGIPGIGFPG--PPGPKGDQGFPGTKGSLGCPGKMGEPGLP 732 Query: 623 NPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPG--NNPIFPRI 680 GL E + +P G G P N S H E G P P Sbjct: 733 GKPGLPGAK-----GEPAVAMPGGPGTPGF-PGERGN-----SGEHGEIGLPGLPGLPGT 781 Query: 681 PVEGPLSPSRGDFPKGIPP--QMGPGRELEFGMVPSGMKGDVNLNVNMGSNSQMIPQKMR 738 P L RGD + PP Q PGR +E P G +G LN G Q+ R Sbjct: 782 PGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG---PRGAQGLPGLNGLKG-------QQGR 831 Query: 739 EAGAGPEEMLKLR-------PG--GSDMLPAQQ-KMVPLPFGEHPQQEYGMGPRPFLPMS 788 GP+ + PG GS +P Q +M PL +P +GP Sbjct: 832 RGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGP------- 884 Query: 789 QGPGSNS--GLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPL 846 PG + G+ IGP P P NP + P QRG Sbjct: 885 --PGEDGVIGMMGFPGAIGP-----------PGPPGNPGT---------PGQRG------ 916 Query: 847 DISVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGMLAGPAAAASIK 906 SPGI +K Q +P G+ +P PS+++ ++ K Sbjct: 917 ----------SPGIPGVKG----QRGTPGAKGEQGDKGNPG-PSEISHVIGD-------K 954 Query: 907 SPPVLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMASPAMLGNVE 966 P L A +P + +P PG+ P P G++ Sbjct: 955 GEPGLKGFAGNPGEKGNRGVPG--------------MPGLKGLKGLPGPAGPPGPRGDLG 1000 Query: 967 SGGPPPPTASQPASVNIPGSLPSSTPYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYH 1026 S G P +P IPGS M MP S Sbjct: 1001 STGNP----GEPGLRGIPGS--------------------------MGNMGMPGS----- 1025 Query: 1027 DAIKTVASSDDDSPPARSPNLPSMNNMPGMGINTQNPRIS-GPNPVVPMPTLSPMGMTQP 1085 K + A P LP ++ + G + P S G P P PT P G+ Sbjct: 1026 ---KGKRGTLGFPGRAGRPGLPGIHGLQG---DKGEPGYSEGTRPGPPGPTGDP-GLPGD 1078 Query: 1086 LSHSNQMPSPNAVGPNIP--PHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQ---- 1139 + +M P G P P G P PG G P P G +GF Sbjct: 1079 MGKKGEMGQPGPPGHLGPAGPEGAPGSPG--------SPGLPGKPG-PHGDLGFKGIKGL 1129 Query: 1140 -GFPPVQSPPQQVPFPHN-GPSG-----GQGSFPGGMGFPGEGPLGRPSNLPQSSADAAL 1192 G P ++ PP FP + GP G G+ PG G GE L R P+ + A Sbjct: 1130 LGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQG 1189 Query: 1193 CK-----PGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGATGIPEFDLSRIIPSEK-PS 1246 K PG PG P +G++ P G TGI F +P P Sbjct: 1190 AKGDRGAPGFPGLPGRKGAMGDAGPR-------------GPTGIEGFPGPPGLPGAIIPG 1236 Query: 1247 QTLQYFPRGEVPGRKQPQGPGPGFSHMQGMMGEQAPRMGLALPGMGGPGPVGTPDIPLGT 1306 QT P G P PGP SH+ G+ G++ MG PGP G P GT Sbjct: 1237 QTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKG--------SMGHPGPKGPP----GT 1284 Query: 1307 APSMPGHNPMRPPAFLQQGMMGPHHRMMSPAQSTMPG---QPTLMSNPAAAVGMIPGKDR 1363 A G MGP R+ +P +PG P P + G+ Sbjct: 1285 A-----------------GDMGPPGRLGAPGTPGLPGPRGDPGFQGFPG-----VKGEKG 1322 Query: 1364 GPA--GLYTHPGPVGSPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNP 1421 P G PGP+G G ++G G + I +P P G + GM G PG P Sbjct: 1323 NPGFLGSIGPPGPIGPKGPP-GVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPP 1381 Query: 1422 GNM 1424 GN+ Sbjct: 1382 GNL 1384 Score = 110 bits (276), Expect = 7e-24 Identities = 251/990 (25%), Positives = 332/990 (33%), Gaps = 199/990 (20%) Query: 516 PPYQMTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPGS--QMRLPGFAGMINSE- 572 P + +P PG T P+ + +P +G P +PG+ +PG AG+ + Sbjct: 99 PGFSGSPGLPGTPGNTGPYGL-VGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKG 157 Query: 573 ---MEGPNVPNPASRPGLSGVSWPDDVPKIPD--GRNFPPGQ-GIFSGPGR-GERFPNPQ 625 E + PGL G P +P P G PPG G F PG G R P Sbjct: 158 APAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGP--- 214 Query: 626 GLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIFPRIPVEGP 685 + + E+ +G ++G+ P P + + GP Sbjct: 215 -------KGHMGERVIGHKGERGVKGLTG----------------PPGPPGTVIVTLTGP 251 Query: 686 -----LSPSRGDFPKGIPPQMGPGRELEFGMVPSGMKGDVNLNVNMGSNS--------QM 732 L +GD KG + GP PSG+ G+ + GS Q Sbjct: 252 DNRTDLKGEKGD--KGAMGEPGPPG-------PSGLPGE-----SYGSEKGAPGDPGLQG 297 Query: 733 IPQKMREAGAGPEEMLKLRPG-----GSDMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPM 787 P K G E +K G G D + Q+ + P P + Y Sbjct: 298 KPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEG 357 Query: 788 SQGPGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLD 847 + GP G R + P GP P +P +P S+ L AP G K Sbjct: 358 TPGPPGPRGARGPQGPSGP-----------PGVPGSPGSSRPGLRGAPGWPGLKGSK--- 403 Query: 848 ISVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGMLAGPAAAASIKS 907 + PG + + +P GSP G SP P G P K Sbjct: 404 -----GERGRPGKDAMGTP----------GSP-GCAGSPGLPGS-PGPPGPPGDIVFRKG 446 Query: 908 PPVLGSAAASPVHLKSPSLPAPS-----PGWTSSPKPPLQSP-------------GIPPN 949 PP P +L SP +P PG + P + P GIP Sbjct: 447 PP---GDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGR 503 Query: 950 HKAPLTMASPAMLGNVESGGPP--PPTASQPASVNIPG-SLPSSTPYTMPPEPTLSQNPL 1006 A SP GN G P P P G +L +P +P L P Sbjct: 504 QGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPG 563 Query: 1007 SIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPAR-----SPNLPSMNNMPGMGINTQ 1061 + + P + D PP SP PG G + Sbjct: 564 RKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGE 623 Query: 1062 NPRISGPNPVVPMPTLSPMGMTQPLSH-SNQMPSPNAVGPNIPP-HGVPMGPGLMSHNPI 1119 P + G V P P G P S P P GP PP H P GP + + Sbjct: 624 -PGLQGTQGVPGAP--GPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGS-- 678 Query: 1120 MGHGSQEPPMVPQGRMGFPQ-GFPPVQSPPQQVPFPHNGPSGGQGSFPGGMGFPGEGPLG 1178 +G P G G P GFP P FP G G G PG MG PG G Sbjct: 679 LGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFP--GTKGSLGC-PGKMGEPGLP--G 733 Query: 1179 RPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGATGIP------ 1232 +P LP + + A+ PGGPG P GNS + E+ PG G+P Sbjct: 734 KPG-LPGAKGEPAVAMPGGPGTPGFPGERGNS-------GEHGEIGLPGLPGLPGTPGNE 785 Query: 1233 EFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQG-PG-PGFSHMQGMMGEQAPRMGLALPG 1290 D R P + Q P + G + QG PG G QG G+ P+ +PG Sbjct: 786 GLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPG 845 Query: 1291 M---GGPGPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMSPAQSTMPGQPTL 1347 + G PG G+P I PGH QG MGP Q PG P + Sbjct: 846 LDRSGFPGETGSPGI--------PGH----------QGEMGP------LGQRGYPGNPGI 881 Query: 1348 MSNPA--AAVGMI--PGK--DRGPAGLYTHPGPVGSPGM--------MMSMQGMMGPQQN 1393 + P +GM+ PG GP G PG GSPG+ +G G + N Sbjct: 882 LGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGN 941 Query: 1394 IMIPPQMRPRGMAADVGMGGFSQGPGNPGN 1423 G + G+ GF+ PG GN Sbjct: 942 PGPSEISHVIGDKGEPGLKGFAGNPGEKGN 971 Score = 107 bits (267), Expect = 8e-23 Identities = 309/1274 (24%), Positives = 408/1274 (32%), Gaps = 241/1274 (18%) Query: 290 GSPASSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGEPPTLG-ENP 348 G+PA + D G P A P P PP PP G P +G P Sbjct: 157 GAPAKEEDIELDAKGDPGLPG--APGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGP 214 Query: 349 DG-LSQEQLEHR-ERSLQTLRD--------IQRMLFPDEKEFTGAQSG-----------G 387 G + + + H+ ER ++ L I + PD + + G G Sbjct: 215 KGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274 Query: 388 PQQNPGVLDGPQKKPEGPIQAMMAQSQSLGKGPGPRTDVGAPFGPQGHRDVPFSPDEMVP 447 P PG G +K G L PG G P G +G + P M Sbjct: 275 PSGLPGESYGSEKGAPG--------DPGLQGKPGKDGVPGFP-GSEGVKGNRGFPGLMGE 325 Query: 448 PSMNSQSGTIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGP 507 + Q G IGP T E+Y+ + K ++ + Q GP Sbjct: 326 DGIKGQKGDIGPPGFRGPT-----------EYYDTYQEKGDEGTPGPPGPRGARGPQ-GP 373 Query: 508 RGVVRGPPPPYQMTPSEGWAPGGT----------EPFSDGINMPHSLPPRGMAPHPNMPG 557 G P P P APG P D + P S G A P +PG Sbjct: 374 SGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGS---PGCAGSPGLPG 430 Query: 558 S------------------QMRLPGFAGMINSE-MEGPN------------VPNPASRPG 586 S LPG+ G ++GP +P P PG Sbjct: 431 SPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPG 490 Query: 587 LSGVSWPDDVPK------IPDGRNFPPGQGIFSGPGRGERFPNPQG---LSEEMFQQQLA 637 L G+ +P + P G+ PG FP QG L E + Sbjct: 491 LPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPG----FPGAQGDPGLKGEKGETLQP 546 Query: 638 EKQLGLP--PGM-------AMEGIR--------PSMEMNRMIPGSQRHMEPGNNPIFPRI 680 E Q+G+P PG+ ++GI P + + G + P +P P Sbjct: 547 EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS 606 Query: 681 PVEGPLSPSRGDFPKGIPPQMGPGRELEFGMVPSGMKGDVNLNVNMGSNSQMIPQKMREA 740 P GP P+ P G PQ PG + G+ G G G S P Sbjct: 607 P--GPAGPAG---PPGYGPQGEPGLQGTQGV--PGAPGPPGEAGPRGELSVSTPVPGPPG 659 Query: 741 GAGPEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPMSQGPGSNSGLRNL 800 GP P G +P P P E G+ P P GP + G Sbjct: 660 PPGPPG--HPGPQGPPGIPGSLGKCGDPGLPGPDGEPGI-PGIGFPGPPGPKGDQGFPGT 716 Query: 801 REPIG-PDQRTNSRLSHMPPLPLNPSSNPTSLNTAP-----PVQRGLGRKPLDISVAG-- 852 + +G P + L P LP ++ P P +RG + +I + G Sbjct: 717 KGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLP 776 Query: 853 SQVHSPGINPLKSPTMHQVQSPMLGS---PSGNLKSPQTPSQLAGMLA-----GPAAAAS 904 +PG L P Q G P ++ P+ L G+ G Sbjct: 777 GLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTG 836 Query: 905 IKSPPVLGSAAAS--PVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMASPA-- 960 K P + S P SP +P PL G P N P + P Sbjct: 837 PKGDPGIPGLDRSGFPGETGSPGIPGHQ-----GEMGPLGQRGYPGN---PGILGPPGED 888 Query: 961 ----MLGNVESGGPPPP-----TASQPASVNIPGSLPSSTPYTMPPEPTLSQNPLSIMMS 1011 M+G + GPP P T Q S IPG E NP S Sbjct: 889 GVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP---S 945 Query: 1012 RMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMGINTQNPRISGP--- 1068 +S P +K A + + P +P + + G+ P G Sbjct: 946 EISHVIGDKGEP----GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGS 1001 Query: 1069 --NPVVP----MP-TLSPMGMTQPLSHSNQMPSPNAVG-PNIPP-HGVPMGPGLMSHNPI 1119 NP P +P ++ MGM + P G P +P HG+ G P Sbjct: 1002 TGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKG----EPG 1057 Query: 1120 MGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPSGGQGSFPGGMGFPG-EGPLG 1178 G++ P P G G P Q P H GP+G +G+ PG G PG G G Sbjct: 1058 YSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGA-PGSPGSPGLPGKPG 1116 Query: 1179 RPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGATGIP-EFDLS 1237 +L L PG G P G+ P ++ I PG G E L Sbjct: 1117 PHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGI-PGPAGEKGETGLL 1175 Query: 1238 RIIPSEKPSQTLQYFPRGEVPGRKQPQG----PG-PGFSHMQGMMGEQAPRMGLALPGMG 1292 R P PRG PG + +G PG PG +G MG+ PR + G Sbjct: 1176 RAPPG----------PRGN-PGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGF- 1223 Query: 1293 GPGPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPA 1352 PGP G P +PG Q G GP P PG P P Sbjct: 1224 -PGPPGLP------GAIIPG----------QTGNRGP------PGSRGSPGAPGPPGPPG 1260 Query: 1353 AAVGMIPGKDRGPAGLYTHPGPVGSPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMG 1412 + V I G D+G G HPGP G PG G MGP + P G D G Sbjct: 1261 SHVIGIKG-DKGSMG---HPGPKGPPGTA----GDMGPPGRLGAPGTPGLPGPRGDPGFQ 1312 Query: 1413 GFSQGPGNPGNMMF 1426 GF G GN F Sbjct: 1313 GFPGVKGEKGNPGF 1326 Score = 67.4 bits (163), Expect = 9e-11 Identities = 192/808 (23%), Positives = 260/808 (32%), Gaps = 162/808 (20%) Query: 254 LQPTPPIPAPAPKPAAPPRPLDRESPGVENKL-------IP----SVGSPASSTPLPPDG 302 L + P+P P P P P + PG+ L +P G P P PP Sbjct: 648 LSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGP 707 Query: 303 TGPNSTPNNRAVTPVSQGSNSSSADPKAPPPP--PVSSGEPPTL---GENPDGLSQEQLE 357 G P + S G +P P P P + GEP G G E+ Sbjct: 708 KGDQGFPGTKG----SLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGN 763 Query: 358 HRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQ--NPGVLDGPQKKPEGP--------IQ 407 E L + + E G P Q PG P + EGP + Sbjct: 764 SGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLN 823 Query: 408 AMMAQSQSLGKGPGPRTDVGAPFGPQGHRDVPFSPDEMVPPSMNSQSGTIGPDHLDHMTP 467 + Q GK GP+ D G P D P E P + G +GP Sbjct: 824 GLKGQQGRRGK-TGPKGDPGIP-----GLDRSGFPGETGSPGIPGHQGEMGP-------- 869 Query: 468 EQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPPPPYQM-TPSEGW 526 L Q Y + +D ++ G G + P PP TP + Sbjct: 870 -------LGQRGYPGNPG------ILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRG 916 Query: 527 APG-----------------------GTEPFSDGINMPHSLPPRGMAPHPNMPGSQMRLP 563 +PG G S I +G A +P G++ +P Sbjct: 917 SPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNR-GVP 975 Query: 564 GFAGMINSEMEGPNVPNPASRPGLSGVSWPDDVPKIPDGRNFP--------PG----QGI 611 G G+ + +P PA PG G P P R P PG +G Sbjct: 976 GMPGLKGLK----GLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGT 1031 Query: 612 FSGPGRGER--FPNPQGLSEEMFQQQLAEKQLGLPPGMAME-GIRPSM----EMNRMIPG 664 PGR R P GL + + +E PPG + G+ M EM + PG Sbjct: 1032 LGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQ--PG 1089 Query: 665 SQRHMEPGNNPIFPRIPVEGPLSPSRGDFPKGIPPQMGPGRELEFGMV-----PSGMKGD 719 H+ P P P SP G+P + GP +L F + P G++G Sbjct: 1090 PPGHLGPAG-------PEGAPGSPG----SPGLPGKPGPHGDLGFKGIKGLLGPPGIRGP 1138 Query: 720 VNLNVNMGSNSQM--IPQKMREAGAGPEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQQEY 777 L GS M + R+ GP G + +L A P + + + Sbjct: 1139 PGLPGFPGSPGPMGIRGDQGRDGIPGPAG----EKGETGLLRAPPGPRGNPGAQGAKGDR 1194 Query: 778 GMGPRPFLPMSQGPGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNPSS--NPTSLNTAP 835 G P LP +G ++G P GP + + P P P + + N P Sbjct: 1195 GAPGFPGLPGRKGAMGDAG------PRGP-----TGIEGFPGPPGLPGAIIPGQTGNRGP 1243 Query: 836 PVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGS-----PSGNLKSPQTPS 890 P RG P GS H GI K H G+ P G L +P TP Sbjct: 1244 PGSRGSPGAPGPPGPPGS--HVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPG 1301 Query: 891 QLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAP-----SPGWTSSPKPPLQSPG 945 L GP + P + +P L S P P PG P L+ Sbjct: 1302 -----LPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDP-GTLKIIS 1355 Query: 946 IPPNHKAPLTMASPAMLGNVESGGPPPP 973 +P + P T P M G E G P PP Sbjct: 1356 LPGSPGPPGTPGEPGMQG--EPGPPGPP 1381 Score = 60.1 bits (144), Expect = 1e-08 Identities = 236/982 (24%), Positives = 304/982 (30%), Gaps = 209/982 (21%) Query: 260 IPAPAPKPAAPPRPLDRESPGVENKLIPSVGSPASSTPLPPDGTGPNSTPNNRAVTPV-- 317 +P P + A D+ PG S GSP + P P G GP P + V Sbjct: 579 LPGPKGELALSGEKGDQGPPGDPG----SPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPG 634 Query: 318 ---------SQGSNSSSADPKAPPPPPVSSGEPPTLGENPDGLSQEQLEHRERSLQTLRD 368 +G S S PP PP G P G P G+ + + L Sbjct: 635 APGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQG--PPGIPGSLGKCGDPGLPG--- 689 Query: 369 IQRMLFPD-EKEFTGAQSGGPQQNPGVLDGPQKKPEGPIQAMMAQSQSLGKG--PGPRTD 425 PD E G GP G P K M + GK PG + + Sbjct: 690 ------PDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGE 743 Query: 426 --VGAPFGP-----QGHRDVPFSPDEMVPPSMNSQSGTIGPDHLDHM-----TPEQIAWL 473 V P GP G R E+ P + GT G + LD P Sbjct: 744 PAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQ 803 Query: 474 KLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPPPPYQMTPSEGWAPGGTEP 533 E R Q + Q + GP+G P P E +PG P Sbjct: 804 GPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPG--IP 861 Query: 534 FSDGINMPHSLPPRGMAPHPNMPG--------SQMRLPGFAGMINSEMEGPNVPNPASRP 585 G + P G +P PG + + GF G I GP P P P Sbjct: 862 GHQG-----EMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAI-----GP--PGPPGNP 909 Query: 586 GLSGVSWPDDVPKIPDGRNFPPGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPP 645 G G +P + R P +G G P P +S + + P Sbjct: 910 GTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGN----PGPSEISHVIGDKG--------EP 957 Query: 646 GMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIFPRIPVEGPLSPSRGDFPKGIPPQMGPGR 705 G+ P + NR +PG PG + KG+P G Sbjct: 958 GLKGFAGNPGEKGNRGVPGM-----PGLKGL------------------KGLPGPAG--- 991 Query: 706 ELEFGMVPSGMKGDVNLNVNMGS-NSQMIPQKMREAGAGPEEMLKLRPGGSDMLPAQQKM 764 P G +GD+ N G + IP M G + + G+ P + Sbjct: 992 -------PPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKR----GTLGFPGRAGR 1040 Query: 765 VPLP-----FGEHPQQEYGMGPRPFLPMSQG----PGSNSGLRNLREPIGPDQRTNSRLS 815 LP G+ + Y G RP P G PG + +P GP Sbjct: 1041 PGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQP-GPPGHLG---- 1095 Query: 816 HMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPM 875 P P P S P GL KP G + GI L P P Sbjct: 1096 -----PAGPEGAPGS-----PGSPGLPGKPGPHGDLGFK----GIKGLLGP-------PG 1134 Query: 876 LGSPSGNLKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTS 935 + P G P +P + + G I P G + + L++P P +PG Sbjct: 1135 IRGPPGLPGFPGSPGPMG--IRGDQGRDGIPGP--AGEKGETGL-LRAPPGPRGNPG-AQ 1188 Query: 936 SPKPPLQSPGIPPNHKAPLTMASPAMLGNVESGGPPPPTASQ--PASVNIPGS-LPSSTP 992 K +PG P P G + GP PT + P +PG+ +P T Sbjct: 1189 GAKGDRGAPGFP---------GLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTG 1239 Query: 993 YTMPPEPTLSQNPLSIMMSRMSKFAM-PSSTPLYH-DAIKTVASSDDDSPPARSPNLPSM 1050 PP SR S A P P H IK S P P Sbjct: 1240 NRGPPG------------SRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGD 1287 Query: 1051 NNMPGMGINTQNPRISGP-NPVVPMPTLSP--------MGMTQPLSHSNQMPSPNAVGPN 1101 PG R+ P P +P P P G + P +GP Sbjct: 1288 MGPPG--------RLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPK 1339 Query: 1102 IPPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPSGG 1161 PP GV PG + I GS PP P G G QG P PP + GP G Sbjct: 1340 GPP-GVRGDPGTL--KIISLPGSPGPPGTP-GEPGM-QGEPGPPGPPGNL-----GPCGP 1389 Query: 1162 QGSFPGGMGFPG-EGPLGRPSN 1182 +G PG G PG GP G N Sbjct: 1390 RGK-PGKDGKPGTPGPAGEKGN 1410 Score = 54.3 bits (129), Expect = 8e-07 Identities = 80/277 (28%), Positives = 103/277 (37%), Gaps = 46/277 (16%) Query: 1161 GQGSFPGGMGFPGEGPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLG-NSMPSVFTDPD 1219 G+ FPG G PG+ P LP PG PG S V G + +P P Sbjct: 49 GEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGF--PGLPGLTGSKGVRGISGLPGFSGSPG 106 Query: 1220 LQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPGPGFSHMQGMMGE 1279 L PG TG + L +P S+ Q FP +PG G PG + ++G G Sbjct: 107 LPGT--PGNTG--PYGLVG-VPGCSGSKGEQGFP--GLPGTLGYPGI-PGAAGLKGQKGA 158 Query: 1280 QAPRMGLALPGMGGPGPVGTPDIPLGT--APSMPGH-NPMRPPAFLQ-QGMMGPHHRMMS 1335 A + L G PG G P P G P PG P PP F G MGP Sbjct: 159 PAKEEDIELDAKGDPGLPGAPG-PQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPR----- 212 Query: 1336 PAQSTMPGQPTLMSNPAAAVG--MIPGK-DRGPAGLYTHPGPVGS-------PGMMMSMQ 1385 P +G +I K +RG GL PGP G+ P ++ Sbjct: 213 --------------GPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLK 258 Query: 1386 GMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 G G + + P P G+ + G PG+PG Sbjct: 259 GEKGDKGAMGEPGPPGPSGLPGE-SYGSEKGAPGDPG 294 Score = 50.8 bits (120), Expect = 9e-06 Identities = 83/301 (27%), Positives = 113/301 (37%), Gaps = 45/301 (14%) Query: 1153 FPHNGPSGGQGSFPGGMGFPG-EGPLGRP--------------SNLPQSSADAALCKPGG 1197 FP S GQ F G G PG +GP G P S LP S L PG Sbjct: 53 FPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGL--PGT 110 Query: 1198 PGGPDSFTVLGNSMPSVFTDPDLQEVI-RPGATGIPEFDLSRIIPSEK----PSQTLQYF 1252 PG + ++G +P Q PG G P + + +K + ++ Sbjct: 111 PGNTGPYGLVG--VPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELD 168 Query: 1253 PRGE--VPGRKQPQG-PG-PGFSHMQGMMGEQAPRMGLALPGMGGP----GPVGTPDIPL 1304 +G+ +PG PQG PG PGF G +G P PG GP G +G I Sbjct: 169 AKGDPGLPGAPGPQGLPGPPGF---PGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGH 225 Query: 1305 GTAPSMPG-HNPMRPPAFLQQGMMGPHHRMMSPAQS------TMPGQPTLMSNPAAAVGM 1357 + G P PP + + GP +R + PG P P + G Sbjct: 226 KGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGS 285 Query: 1358 IPGKDRGPAGLYTHPGPVGSPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQG 1417 G G GL PG G PG S +G+ G + + + +G D+G GF +G Sbjct: 286 EKGAP-GDPGLQGKPGKDGVPGFPGS-EGVKGNRGFPGLMGEDGIKGQKGDIGPPGF-RG 342 Query: 1418 P 1418 P Sbjct: 343 P 343 Score = 50.1 bits (118), Expect = 2e-05 Identities = 99/398 (24%), Positives = 140/398 (35%), Gaps = 70/398 (17%) Query: 1047 LPSMNNMPGMGINTQNPRISGPNPVVPMPTLSPMGMTQPLSHSNQMPSPNAVGPNIPPHG 1106 LP + PG+ P +GP +V +P S + P G P G Sbjct: 98 LPGFSGSPGL---PGTPGNTGPYGLVGVPGCS--------GSKGEQGFPGLPGTLGYP-G 145 Query: 1107 VPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPSGGQGSFP 1166 +P GL ++ + +G G P G P Q P FP GP G G P Sbjct: 146 IPGAAGLKGQKGAPAK-EEDIELDAKGDPGLP-GAPGPQGLPGPPGFP--GPVGPPGP-P 200 Query: 1167 GGMGFPGE-GPLGRPSNLPQS----SADAALCKPGGPGGPDSFTVLGNSMPSVFTD---- 1217 G GFPG GP G ++ + + + GP GP ++ + P TD Sbjct: 201 GFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGE 260 Query: 1218 -PDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPGPGFSHMQGM 1276 D + PG G PS P ++ Y PG QG PG + G Sbjct: 261 KGDKGAMGEPGPPG----------PSGLPGES--YGSEKGAPGDPGLQGK-PGKDGVPGF 307 Query: 1277 MGEQAPRMGLALPGMGGPGPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMSP 1336 G + + PG+ G + +G PP F +G + Sbjct: 308 PGSEGVKGNRGFPGLMGEDGIKGQKGDIG------------PPGF--RGPTEYYDTYQEK 353 Query: 1337 AQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGL-----YTHPGPVGSPGM--MMSMQGMMG 1389 PG P P A G P GP G+ + PG G+PG + +G G Sbjct: 354 GDEGTPGPP----GPRGARG--PQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERG 407 Query: 1390 -PQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPGNMMF 1426 P ++ M P G A G+ G PG PG+++F Sbjct: 408 RPGKDAMGTPGSP--GCAGSPGLPGSPGPPGPPGDIVF 443 Score = 36.2 bits (82), Expect = 0.23 Identities = 29/90 (32%), Positives = 39/90 (43%), Gaps = 15/90 (16%) Query: 1347 LMSNPAAAVGMIPGKDRGPA---------GLYTHPGPVGSPGMM-----MSMQGMMGPQQ 1392 L + PAA+ G + KD+G G PGP GSPG + G GP+ Sbjct: 21 LAAAPAASKGCVC-KDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKG 79 Query: 1393 NIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 +P +G+ G+ GFS PG PG Sbjct: 80 FPGLPGLTGSKGVRGISGLPGFSGSPGLPG 109 Score = 35.8 bits (81), Expect = 0.30 Identities = 64/253 (25%), Positives = 83/253 (32%), Gaps = 49/253 (19%) Query: 234 LPQQPPAP-ANQDQNSSQNTRLQPT-PPIPAP--APKPAAPPRPLDRES----PGVENKL 285 L + PP P N ++ R P P +P A A P P E PG+ + Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233 Query: 286 IPSV----GSPASSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGEP 341 IP G P S P GP P + + + PK PP G P Sbjct: 1234 IPGQTGNRGPPGSRGS--PGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPP 1291 Query: 342 PTLG-ENPDGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPGVLD---- 396 LG GL + + P + F G + G + NPG L Sbjct: 1292 GRLGAPGTPGLPGPRGD-----------------PGFQGFPGVK--GEKGNPGFLGSIGP 1332 Query: 397 ----GPQKKPEGPIQAMMAQSQSLGKGPGPRTDVGAPFGPQGHRDVPFSPDEMVP----- 447 GP+ P + SL PGP G P G QG P P + P Sbjct: 1333 PGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEP-GMQGEPGPPGPPGNLGPCGPRG 1391 Query: 448 -PSMNSQSGTIGP 459 P + + GT GP Sbjct: 1392 KPGKDGKPGTPGP 1404 Score = 33.9 bits (76), Expect = 1.1 Identities = 20/70 (28%), Positives = 28/70 (40%), Gaps = 1/70 (1%) Query: 27 MVRPPTVMSPSGNPQLDSKFSNQGKQGGSASQSQPSPCDSKSGGHTPKALPGPGGSMGLK 86 ++ PP + P G P G +G P P K +A PGP G+ G + Sbjct: 1129 LLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQ 1188 Query: 87 NGAGN-GAKG 95 G+ GA G Sbjct: 1189 GAKGDRGAPG 1198 Score = 31.2 bits (69), Expect = 7.5 Identities = 19/70 (27%), Positives = 29/70 (41%), Gaps = 1/70 (1%) Query: 36 PSGNPQLDSKFSNQGKQGGSASQSQPSPC-DSKSGGHTPKALPGPGGSMGLKNGAGNGAK 94 P G L + +QG G S P P + G+ P+ PG G+ G+ G + Sbjct: 582 PKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGE 641 Query: 95 GKGKRERSIS 104 + E S+S Sbjct: 642 AGPRGELSVS 651 >gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo sapiens] Length = 1494 Score = 113 bits (283), Expect = 1e-24 Identities = 249/963 (25%), Positives = 327/963 (33%), Gaps = 250/963 (25%) Query: 506 GPRGVVRGPPPPYQMTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPGSQMRLPGF 565 G +GV P PP + P + P G P G HP G PG Sbjct: 628 GTQGVPGAPGPPGEAGPRGELSVSTPVPGPPG--------PPGPPGHPGPQGP----PGI 675 Query: 566 AGMINSEMEGPNVPNPASRPGLSGVSWPDDVPKIPDG-RNFPPGQGIFSGPGR-GER-FP 622 G + + P +P P PG+ G+ +P P P G + FP +G PG+ GE P Sbjct: 676 PGSLG-KCGDPGLPGPDGEPGIPGIGFPG--PPGPKGDQGFPGTKGSLGCPGKMGEPGLP 732 Query: 623 NPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPG--NNPIFPRI 680 GL E + +P G G P N S H E G P P Sbjct: 733 GKPGLPGAK-----GEPAVAMPGGPGTPGF-PGERGN-----SGEHGEIGLPGLPGLPGT 781 Query: 681 PVEGPLSPSRGDFPKGIPP--QMGPGRELEFGMVPSGMKGDVNLNVNMGSNSQMIPQKMR 738 P L RGD + PP Q PGR +E P G +G LN G Q+ R Sbjct: 782 PGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG---PRGAQGLPGLNGLKG-------QQGR 831 Query: 739 EAGAGPEEMLKLR-------PG--GSDMLPAQQ-KMVPLPFGEHPQQEYGMGPRPFLPMS 788 GP+ + PG GS +P Q +M PL +P +GP Sbjct: 832 RGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGP------- 884 Query: 789 QGPGSNS--GLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPL 846 PG + G+ IGP P P NP + P QRG Sbjct: 885 --PGEDGVIGMMGFPGAIGP-----------PGPPGNPGT---------PGQRG------ 916 Query: 847 DISVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGMLAGPAAAASIK 906 SPGI +K Q +P G+ +P PS+++ ++ K Sbjct: 917 ----------SPGIPGVKG----QRGTPGAKGEQGDKGNPG-PSEISHVIGD-------K 954 Query: 907 SPPVLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMASPAMLGNVE 966 P L A +P + +P PG+ P P G++ Sbjct: 955 GEPGLKGFAGNPGEKGNRGVPG--------------MPGLKGLKGLPGPAGPPGPRGDLG 1000 Query: 967 SGGPPPPTASQPASVNIPGSLPSSTPYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYH 1026 S G P +P IPGS M MP S Sbjct: 1001 STGNP----GEPGLRGIPGS--------------------------MGNMGMPGS----- 1025 Query: 1027 DAIKTVASSDDDSPPARSPNLPSMNNMPGMGINTQNPRIS-GPNPVVPMPTLSPMGMTQP 1085 K + A P LP ++ + G + P S G P P PT P G+ Sbjct: 1026 ---KGKRGTLGFPGRAGRPGLPGIHGLQG---DKGEPGYSEGTRPGPPGPTGDP-GLPGD 1078 Query: 1086 LSHSNQMPSPNAVGPNIP--PHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQ---- 1139 + +M P G P P G P PG G P P G +GF Sbjct: 1079 MGKKGEMGQPGPPGHLGPAGPEGAPGSPG--------SPGLPGKPG-PHGDLGFKGIKGL 1129 Query: 1140 -GFPPVQSPPQQVPFPHN-GPSG-----GQGSFPGGMGFPGEGPLGRPSNLPQSSADAAL 1192 G P ++ PP FP + GP G G+ PG G GE L R P+ + A Sbjct: 1130 LGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQG 1189 Query: 1193 CK-----PGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGATGIPEFDLSRIIPSEK-PS 1246 K PG PG P +G++ P G TGI F +P P Sbjct: 1190 AKGDRGAPGFPGLPGRKGAMGDAGPR-------------GPTGIEGFPGPPGLPGAIIPG 1236 Query: 1247 QTLQYFPRGEVPGRKQPQGPGPGFSHMQGMMGEQAPRMGLALPGMGGPGPVGTPDIPLGT 1306 QT P G P PGP SH+ G+ G++ MG PGP G P GT Sbjct: 1237 QTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKG--------SMGHPGPKGPP----GT 1284 Query: 1307 APSMPGHNPMRPPAFLQQGMMGPHHRMMSPAQSTMPG---QPTLMSNPAAAVGMIPGKDR 1363 A G MGP R+ +P +PG P P + G+ Sbjct: 1285 A-----------------GDMGPPGRLGAPGTPGLPGPRGDPGFQGFPG-----VKGEKG 1322 Query: 1364 GPA--GLYTHPGPVGSPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNP 1421 P G PGP+G G ++G G + I +P P G + GM G PG P Sbjct: 1323 NPGFLGSIGPPGPIGPKGPP-GVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPP 1381 Query: 1422 GNM 1424 GN+ Sbjct: 1382 GNL 1384 Score = 110 bits (276), Expect = 7e-24 Identities = 251/990 (25%), Positives = 332/990 (33%), Gaps = 199/990 (20%) Query: 516 PPYQMTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPGS--QMRLPGFAGMINSE- 572 P + +P PG T P+ + +P +G P +PG+ +PG AG+ + Sbjct: 99 PGFSGSPGLPGTPGNTGPYGL-VGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKG 157 Query: 573 ---MEGPNVPNPASRPGLSGVSWPDDVPKIPD--GRNFPPGQ-GIFSGPGR-GERFPNPQ 625 E + PGL G P +P P G PPG G F PG G R P Sbjct: 158 APAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGP--- 214 Query: 626 GLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIFPRIPVEGP 685 + + E+ +G ++G+ P P + + GP Sbjct: 215 -------KGHMGERVIGHKGERGVKGLTG----------------PPGPPGTVIVTLTGP 251 Query: 686 -----LSPSRGDFPKGIPPQMGPGRELEFGMVPSGMKGDVNLNVNMGSNS--------QM 732 L +GD KG + GP PSG+ G+ + GS Q Sbjct: 252 DNRTDLKGEKGD--KGAMGEPGPPG-------PSGLPGE-----SYGSEKGAPGDPGLQG 297 Query: 733 IPQKMREAGAGPEEMLKLRPG-----GSDMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPM 787 P K G E +K G G D + Q+ + P P + Y Sbjct: 298 KPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEG 357 Query: 788 SQGPGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLD 847 + GP G R + P GP P +P +P S+ L AP G K Sbjct: 358 TPGPPGPRGARGPQGPSGP-----------PGVPGSPGSSRPGLRGAPGWPGLKGSK--- 403 Query: 848 ISVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGMLAGPAAAASIKS 907 + PG + + +P GSP G SP P G P K Sbjct: 404 -----GERGRPGKDAMGTP----------GSP-GCAGSPGLPGS-PGPPGPPGDIVFRKG 446 Query: 908 PPVLGSAAASPVHLKSPSLPAPS-----PGWTSSPKPPLQSP-------------GIPPN 949 PP P +L SP +P PG + P + P GIP Sbjct: 447 PP---GDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGR 503 Query: 950 HKAPLTMASPAMLGNVESGGPP--PPTASQPASVNIPG-SLPSSTPYTMPPEPTLSQNPL 1006 A SP GN G P P P G +L +P +P L P Sbjct: 504 QGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPG 563 Query: 1007 SIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPAR-----SPNLPSMNNMPGMGINTQ 1061 + + P + D PP SP PG G + Sbjct: 564 RKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGE 623 Query: 1062 NPRISGPNPVVPMPTLSPMGMTQPLSH-SNQMPSPNAVGPNIPP-HGVPMGPGLMSHNPI 1119 P + G V P P G P S P P GP PP H P GP + + Sbjct: 624 -PGLQGTQGVPGAP--GPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGS-- 678 Query: 1120 MGHGSQEPPMVPQGRMGFPQ-GFPPVQSPPQQVPFPHNGPSGGQGSFPGGMGFPGEGPLG 1178 +G P G G P GFP P FP G G G PG MG PG G Sbjct: 679 LGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFP--GTKGSLGC-PGKMGEPGLP--G 733 Query: 1179 RPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGATGIP------ 1232 +P LP + + A+ PGGPG P GNS + E+ PG G+P Sbjct: 734 KPG-LPGAKGEPAVAMPGGPGTPGFPGERGNS-------GEHGEIGLPGLPGLPGTPGNE 785 Query: 1233 EFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQG-PG-PGFSHMQGMMGEQAPRMGLALPG 1290 D R P + Q P + G + QG PG G QG G+ P+ +PG Sbjct: 786 GLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPG 845 Query: 1291 M---GGPGPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMSPAQSTMPGQPTL 1347 + G PG G+P I PGH QG MGP Q PG P + Sbjct: 846 LDRSGFPGETGSPGI--------PGH----------QGEMGP------LGQRGYPGNPGI 881 Query: 1348 MSNPA--AAVGMI--PGK--DRGPAGLYTHPGPVGSPGM--------MMSMQGMMGPQQN 1393 + P +GM+ PG GP G PG GSPG+ +G G + N Sbjct: 882 LGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGN 941 Query: 1394 IMIPPQMRPRGMAADVGMGGFSQGPGNPGN 1423 G + G+ GF+ PG GN Sbjct: 942 PGPSEISHVIGDKGEPGLKGFAGNPGEKGN 971 Score = 107 bits (267), Expect = 8e-23 Identities = 309/1274 (24%), Positives = 408/1274 (32%), Gaps = 241/1274 (18%) Query: 290 GSPASSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGEPPTLG-ENP 348 G+PA + D G P A P P PP PP G P +G P Sbjct: 157 GAPAKEEDIELDAKGDPGLPG--APGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGP 214 Query: 349 DG-LSQEQLEHR-ERSLQTLRD--------IQRMLFPDEKEFTGAQSG-----------G 387 G + + + H+ ER ++ L I + PD + + G G Sbjct: 215 KGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274 Query: 388 PQQNPGVLDGPQKKPEGPIQAMMAQSQSLGKGPGPRTDVGAPFGPQGHRDVPFSPDEMVP 447 P PG G +K G L PG G P G +G + P M Sbjct: 275 PSGLPGESYGSEKGAPG--------DPGLQGKPGKDGVPGFP-GSEGVKGNRGFPGLMGE 325 Query: 448 PSMNSQSGTIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGP 507 + Q G IGP T E+Y+ + K ++ + Q GP Sbjct: 326 DGIKGQKGDIGPPGFRGPT-----------EYYDTYQEKGDEGTPGPPGPRGARGPQ-GP 373 Query: 508 RGVVRGPPPPYQMTPSEGWAPGGT----------EPFSDGINMPHSLPPRGMAPHPNMPG 557 G P P P APG P D + P S G A P +PG Sbjct: 374 SGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGS---PGCAGSPGLPG 430 Query: 558 S------------------QMRLPGFAGMINSE-MEGPN------------VPNPASRPG 586 S LPG+ G ++GP +P P PG Sbjct: 431 SPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPG 490 Query: 587 LSGVSWPDDVPK------IPDGRNFPPGQGIFSGPGRGERFPNPQG---LSEEMFQQQLA 637 L G+ +P + P G+ PG FP QG L E + Sbjct: 491 LPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPG----FPGAQGDPGLKGEKGETLQP 546 Query: 638 EKQLGLP--PGM-------AMEGIR--------PSMEMNRMIPGSQRHMEPGNNPIFPRI 680 E Q+G+P PG+ ++GI P + + G + P +P P Sbjct: 547 EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS 606 Query: 681 PVEGPLSPSRGDFPKGIPPQMGPGRELEFGMVPSGMKGDVNLNVNMGSNSQMIPQKMREA 740 P GP P+ P G PQ PG + G+ G G G S P Sbjct: 607 P--GPAGPAG---PPGYGPQGEPGLQGTQGV--PGAPGPPGEAGPRGELSVSTPVPGPPG 659 Query: 741 GAGPEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPMSQGPGSNSGLRNL 800 GP P G +P P P E G+ P P GP + G Sbjct: 660 PPGPPG--HPGPQGPPGIPGSLGKCGDPGLPGPDGEPGI-PGIGFPGPPGPKGDQGFPGT 716 Query: 801 REPIG-PDQRTNSRLSHMPPLPLNPSSNPTSLNTAP-----PVQRGLGRKPLDISVAG-- 852 + +G P + L P LP ++ P P +RG + +I + G Sbjct: 717 KGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLP 776 Query: 853 SQVHSPGINPLKSPTMHQVQSPMLGS---PSGNLKSPQTPSQLAGMLA-----GPAAAAS 904 +PG L P Q G P ++ P+ L G+ G Sbjct: 777 GLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTG 836 Query: 905 IKSPPVLGSAAAS--PVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMASPA-- 960 K P + S P SP +P PL G P N P + P Sbjct: 837 PKGDPGIPGLDRSGFPGETGSPGIPGHQ-----GEMGPLGQRGYPGN---PGILGPPGED 888 Query: 961 ----MLGNVESGGPPPP-----TASQPASVNIPGSLPSSTPYTMPPEPTLSQNPLSIMMS 1011 M+G + GPP P T Q S IPG E NP S Sbjct: 889 GVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP---S 945 Query: 1012 RMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMGINTQNPRISGP--- 1068 +S P +K A + + P +P + + G+ P G Sbjct: 946 EISHVIGDKGEP----GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGS 1001 Query: 1069 --NPVVP----MP-TLSPMGMTQPLSHSNQMPSPNAVG-PNIPP-HGVPMGPGLMSHNPI 1119 NP P +P ++ MGM + P G P +P HG+ G P Sbjct: 1002 TGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKG----EPG 1057 Query: 1120 MGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPSGGQGSFPGGMGFPG-EGPLG 1178 G++ P P G G P Q P H GP+G +G+ PG G PG G G Sbjct: 1058 YSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGA-PGSPGSPGLPGKPG 1116 Query: 1179 RPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGATGIP-EFDLS 1237 +L L PG G P G+ P ++ I PG G E L Sbjct: 1117 PHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGI-PGPAGEKGETGLL 1175 Query: 1238 RIIPSEKPSQTLQYFPRGEVPGRKQPQG----PG-PGFSHMQGMMGEQAPRMGLALPGMG 1292 R P PRG PG + +G PG PG +G MG+ PR + G Sbjct: 1176 RAPPG----------PRGN-PGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGF- 1223 Query: 1293 GPGPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPA 1352 PGP G P +PG Q G GP P PG P P Sbjct: 1224 -PGPPGLP------GAIIPG----------QTGNRGP------PGSRGSPGAPGPPGPPG 1260 Query: 1353 AAVGMIPGKDRGPAGLYTHPGPVGSPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMG 1412 + V I G D+G G HPGP G PG G MGP + P G D G Sbjct: 1261 SHVIGIKG-DKGSMG---HPGPKGPPGTA----GDMGPPGRLGAPGTPGLPGPRGDPGFQ 1312 Query: 1413 GFSQGPGNPGNMMF 1426 GF G GN F Sbjct: 1313 GFPGVKGEKGNPGF 1326 Score = 67.4 bits (163), Expect = 9e-11 Identities = 192/808 (23%), Positives = 260/808 (32%), Gaps = 162/808 (20%) Query: 254 LQPTPPIPAPAPKPAAPPRPLDRESPGVENKL-------IP----SVGSPASSTPLPPDG 302 L + P+P P P P P + PG+ L +P G P P PP Sbjct: 648 LSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGP 707 Query: 303 TGPNSTPNNRAVTPVSQGSNSSSADPKAPPPP--PVSSGEPPTL---GENPDGLSQEQLE 357 G P + S G +P P P P + GEP G G E+ Sbjct: 708 KGDQGFPGTKG----SLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGN 763 Query: 358 HRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQ--NPGVLDGPQKKPEGP--------IQ 407 E L + + E G P Q PG P + EGP + Sbjct: 764 SGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLN 823 Query: 408 AMMAQSQSLGKGPGPRTDVGAPFGPQGHRDVPFSPDEMVPPSMNSQSGTIGPDHLDHMTP 467 + Q GK GP+ D G P D P E P + G +GP Sbjct: 824 GLKGQQGRRGK-TGPKGDPGIP-----GLDRSGFPGETGSPGIPGHQGEMGP-------- 869 Query: 468 EQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPPPPYQM-TPSEGW 526 L Q Y + +D ++ G G + P PP TP + Sbjct: 870 -------LGQRGYPGNPG------ILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRG 916 Query: 527 APG-----------------------GTEPFSDGINMPHSLPPRGMAPHPNMPGSQMRLP 563 +PG G S I +G A +P G++ +P Sbjct: 917 SPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNR-GVP 975 Query: 564 GFAGMINSEMEGPNVPNPASRPGLSGVSWPDDVPKIPDGRNFP--------PG----QGI 611 G G+ + +P PA PG G P P R P PG +G Sbjct: 976 GMPGLKGLK----GLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGT 1031 Query: 612 FSGPGRGER--FPNPQGLSEEMFQQQLAEKQLGLPPGMAME-GIRPSM----EMNRMIPG 664 PGR R P GL + + +E PPG + G+ M EM + PG Sbjct: 1032 LGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQ--PG 1089 Query: 665 SQRHMEPGNNPIFPRIPVEGPLSPSRGDFPKGIPPQMGPGRELEFGMV-----PSGMKGD 719 H+ P P P SP G+P + GP +L F + P G++G Sbjct: 1090 PPGHLGPAG-------PEGAPGSPG----SPGLPGKPGPHGDLGFKGIKGLLGPPGIRGP 1138 Query: 720 VNLNVNMGSNSQM--IPQKMREAGAGPEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQQEY 777 L GS M + R+ GP G + +L A P + + + Sbjct: 1139 PGLPGFPGSPGPMGIRGDQGRDGIPGPAG----EKGETGLLRAPPGPRGNPGAQGAKGDR 1194 Query: 778 GMGPRPFLPMSQGPGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNPSS--NPTSLNTAP 835 G P LP +G ++G P GP + + P P P + + N P Sbjct: 1195 GAPGFPGLPGRKGAMGDAG------PRGP-----TGIEGFPGPPGLPGAIIPGQTGNRGP 1243 Query: 836 PVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGS-----PSGNLKSPQTPS 890 P RG P GS H GI K H G+ P G L +P TP Sbjct: 1244 PGSRGSPGAPGPPGPPGS--HVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPG 1301 Query: 891 QLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAP-----SPGWTSSPKPPLQSPG 945 L GP + P + +P L S P P PG P L+ Sbjct: 1302 -----LPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDP-GTLKIIS 1355 Query: 946 IPPNHKAPLTMASPAMLGNVESGGPPPP 973 +P + P T P M G E G P PP Sbjct: 1356 LPGSPGPPGTPGEPGMQG--EPGPPGPP 1381 Score = 61.2 bits (147), Expect = 7e-09 Identities = 239/999 (23%), Positives = 307/999 (30%), Gaps = 209/999 (20%) Query: 260 IPAPAPKPAAPPRPLDRESPGVENKLIPSVGSPASSTPLPPDGTGPNSTPNNRAVTPV-- 317 +P P + A D+ PG S GSP + P P G GP P + V Sbjct: 579 LPGPKGELALSGEKGDQGPPGDPG----SPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPG 634 Query: 318 ---------SQGSNSSSADPKAPPPPPVSSGEPPTLGENPDGLSQEQLEHRERSLQTLRD 368 +G S S PP PP G P G P G+ + + L Sbjct: 635 APGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQG--PPGIPGSLGKCGDPGLPG--- 689 Query: 369 IQRMLFPD-EKEFTGAQSGGPQQNPGVLDGPQKKPEGPIQAMMAQSQSLGKG--PGPRTD 425 PD E G GP G P K M + GK PG + + Sbjct: 690 ------PDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGE 743 Query: 426 --VGAPFGP-----QGHRDVPFSPDEMVPPSMNSQSGTIGPDHLDHM-----TPEQIAWL 473 V P GP G R E+ P + GT G + LD P Sbjct: 744 PAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQ 803 Query: 474 KLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPPPPYQMTPSEGWAPGGTEP 533 E R Q + Q + GP+G P P E +PG P Sbjct: 804 GPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPG--IP 861 Query: 534 FSDGINMPHSLPPRGMAPHPNMPG--------SQMRLPGFAGMINSEMEGPNVPNPASRP 585 G + P G +P PG + + GF G I GP P P P Sbjct: 862 GHQG-----EMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAI-----GP--PGPPGNP 909 Query: 586 GLSGVSWPDDVPKIPDGRNFPPGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPP 645 G G +P + R P +G G P P +S + + P Sbjct: 910 GTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGN----PGPSEISHVIGDKG--------EP 957 Query: 646 GMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIFPRIPVEGPLSPSRGDFPKGIPPQMGPGR 705 G+ P + NR +PG PG + KG+P G Sbjct: 958 GLKGFAGNPGEKGNRGVPGM-----PGLKGL------------------KGLPGPAG--- 991 Query: 706 ELEFGMVPSGMKGDVNLNVNMGS-NSQMIPQKMREAGAGPEEMLKLRPGGSDMLPAQQKM 764 P G +GD+ N G + IP M G + + G+ P + Sbjct: 992 -------PPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKR----GTLGFPGRAGR 1040 Query: 765 VPLP-----FGEHPQQEYGMGPRPFLPMSQG----PGSNSGLRNLREPIGPDQRTNSRLS 815 LP G+ + Y G RP P G PG + +P GP Sbjct: 1041 PGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQP-GPPGHLG---- 1095 Query: 816 HMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPM 875 P P P S P GL KP G + GI L P P Sbjct: 1096 -----PAGPEGAPGS-----PGSPGLPGKPGPHGDLGFK----GIKGLLGP-------PG 1134 Query: 876 LGSPSGNLKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTS 935 + P G P +P + + G I P G + + L++P P +PG Sbjct: 1135 IRGPPGLPGFPGSPGPMG--IRGDQGRDGIPGP--AGEKGETGL-LRAPPGPRGNPG-AQ 1188 Query: 936 SPKPPLQSPGIPPNHKAPLTMASPAMLGNVESGGPPPPTASQ--PASVNIPGS-LPSSTP 992 K +PG P P G + GP PT + P +PG+ +P T Sbjct: 1189 GAKGDRGAPGFP---------GLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTG 1239 Query: 993 YTMPPEPTLSQNPLSIMMSRMSKFAM-PSSTPLYH-DAIKTVASSDDDSPPARSPNLPSM 1050 PP SR S A P P H IK S P P Sbjct: 1240 NRGPPG------------SRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGD 1287 Query: 1051 NNMPGMGINTQNPRISGP-NPVVPMPTLSP--------MGMTQPLSHSNQMPSPNAVGPN 1101 PG R+ P P +P P P G + P +GP Sbjct: 1288 MGPPG--------RLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPK 1339 Query: 1102 IPPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPSGG 1161 PP GV PG + I GS PP P G G QG P PP + GP G Sbjct: 1340 GPP-GVRGDPGTL--KIISLPGSPGPPGTP-GEPGM-QGEPGPPGPPGNL-----GPCGP 1389 Query: 1162 QGSFPGGMGFPG-EGPLGRPSNLPQSSADAALCKPGGPG 1199 +G PG G PG GP G N G PG Sbjct: 1390 RGK-PGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPG 1427 Score = 54.3 bits (129), Expect = 8e-07 Identities = 80/277 (28%), Positives = 103/277 (37%), Gaps = 46/277 (16%) Query: 1161 GQGSFPGGMGFPGEGPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLG-NSMPSVFTDPD 1219 G+ FPG G PG+ P LP PG PG S V G + +P P Sbjct: 49 GEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGF--PGLPGLTGSKGVRGISGLPGFSGSPG 106 Query: 1220 LQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPGPGFSHMQGMMGE 1279 L PG TG + L +P S+ Q FP +PG G PG + ++G G Sbjct: 107 LPGT--PGNTG--PYGLVG-VPGCSGSKGEQGFP--GLPGTLGYPGI-PGAAGLKGQKGA 158 Query: 1280 QAPRMGLALPGMGGPGPVGTPDIPLGT--APSMPGH-NPMRPPAFLQ-QGMMGPHHRMMS 1335 A + L G PG G P P G P PG P PP F G MGP Sbjct: 159 PAKEEDIELDAKGDPGLPGAPG-PQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPR----- 212 Query: 1336 PAQSTMPGQPTLMSNPAAAVG--MIPGK-DRGPAGLYTHPGPVGS-------PGMMMSMQ 1385 P +G +I K +RG GL PGP G+ P ++ Sbjct: 213 --------------GPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLK 258 Query: 1386 GMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 G G + + P P G+ + G PG+PG Sbjct: 259 GEKGDKGAMGEPGPPGPSGLPGE-SYGSEKGAPGDPG 294 Score = 50.8 bits (120), Expect = 9e-06 Identities = 83/301 (27%), Positives = 113/301 (37%), Gaps = 45/301 (14%) Query: 1153 FPHNGPSGGQGSFPGGMGFPG-EGPLGRP--------------SNLPQSSADAALCKPGG 1197 FP S GQ F G G PG +GP G P S LP S L PG Sbjct: 53 FPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGL--PGT 110 Query: 1198 PGGPDSFTVLGNSMPSVFTDPDLQEVI-RPGATGIPEFDLSRIIPSEK----PSQTLQYF 1252 PG + ++G +P Q PG G P + + +K + ++ Sbjct: 111 PGNTGPYGLVG--VPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELD 168 Query: 1253 PRGE--VPGRKQPQG-PG-PGFSHMQGMMGEQAPRMGLALPGMGGP----GPVGTPDIPL 1304 +G+ +PG PQG PG PGF G +G P PG GP G +G I Sbjct: 169 AKGDPGLPGAPGPQGLPGPPGF---PGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGH 225 Query: 1305 GTAPSMPG-HNPMRPPAFLQQGMMGPHHRMMSPAQS------TMPGQPTLMSNPAAAVGM 1357 + G P PP + + GP +R + PG P P + G Sbjct: 226 KGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGS 285 Query: 1358 IPGKDRGPAGLYTHPGPVGSPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQG 1417 G G GL PG G PG S +G+ G + + + +G D+G GF +G Sbjct: 286 EKGAP-GDPGLQGKPGKDGVPGFPGS-EGVKGNRGFPGLMGEDGIKGQKGDIGPPGF-RG 342 Query: 1418 P 1418 P Sbjct: 343 P 343 Score = 50.1 bits (118), Expect = 2e-05 Identities = 99/398 (24%), Positives = 140/398 (35%), Gaps = 70/398 (17%) Query: 1047 LPSMNNMPGMGINTQNPRISGPNPVVPMPTLSPMGMTQPLSHSNQMPSPNAVGPNIPPHG 1106 LP + PG+ P +GP +V +P S + P G P G Sbjct: 98 LPGFSGSPGL---PGTPGNTGPYGLVGVPGCS--------GSKGEQGFPGLPGTLGYP-G 145 Query: 1107 VPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPSGGQGSFP 1166 +P GL ++ + +G G P G P Q P FP GP G G P Sbjct: 146 IPGAAGLKGQKGAPAK-EEDIELDAKGDPGLP-GAPGPQGLPGPPGFP--GPVGPPGP-P 200 Query: 1167 GGMGFPGE-GPLGRPSNLPQS----SADAALCKPGGPGGPDSFTVLGNSMPSVFTD---- 1217 G GFPG GP G ++ + + + GP GP ++ + P TD Sbjct: 201 GFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGE 260 Query: 1218 -PDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPGPGFSHMQGM 1276 D + PG G PS P ++ Y PG QG PG + G Sbjct: 261 KGDKGAMGEPGPPG----------PSGLPGES--YGSEKGAPGDPGLQGK-PGKDGVPGF 307 Query: 1277 MGEQAPRMGLALPGMGGPGPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMSP 1336 G + + PG+ G + +G PP F +G + Sbjct: 308 PGSEGVKGNRGFPGLMGEDGIKGQKGDIG------------PPGF--RGPTEYYDTYQEK 353 Query: 1337 AQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGL-----YTHPGPVGSPGM--MMSMQGMMG 1389 PG P P A G P GP G+ + PG G+PG + +G G Sbjct: 354 GDEGTPGPP----GPRGARG--PQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERG 407 Query: 1390 -PQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPGNMMF 1426 P ++ M P G A G+ G PG PG+++F Sbjct: 408 RPGKDAMGTPGSP--GCAGSPGLPGSPGPPGPPGDIVF 443 Score = 36.2 bits (82), Expect = 0.23 Identities = 29/90 (32%), Positives = 39/90 (43%), Gaps = 15/90 (16%) Query: 1347 LMSNPAAAVGMIPGKDRGPA---------GLYTHPGPVGSPGMM-----MSMQGMMGPQQ 1392 L + PAA+ G + KD+G G PGP GSPG + G GP+ Sbjct: 21 LAAAPAASKGCVC-KDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKG 79 Query: 1393 NIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 +P +G+ G+ GFS PG PG Sbjct: 80 FPGLPGLTGSKGVRGISGLPGFSGSPGLPG 109 Score = 35.8 bits (81), Expect = 0.30 Identities = 64/253 (25%), Positives = 83/253 (32%), Gaps = 49/253 (19%) Query: 234 LPQQPPAP-ANQDQNSSQNTRLQPT-PPIPAP--APKPAAPPRPLDRES----PGVENKL 285 L + PP P N ++ R P P +P A A P P E PG+ + Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233 Query: 286 IPSV----GSPASSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGEP 341 IP G P S P GP P + + + PK PP G P Sbjct: 1234 IPGQTGNRGPPGSRGS--PGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPP 1291 Query: 342 PTLG-ENPDGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPGVLD---- 396 LG GL + + P + F G + G + NPG L Sbjct: 1292 GRLGAPGTPGLPGPRGD-----------------PGFQGFPGVK--GEKGNPGFLGSIGP 1332 Query: 397 ----GPQKKPEGPIQAMMAQSQSLGKGPGPRTDVGAPFGPQGHRDVPFSPDEMVP----- 447 GP+ P + SL PGP G P G QG P P + P Sbjct: 1333 PGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEP-GMQGEPGPPGPPGNLGPCGPRG 1391 Query: 448 -PSMNSQSGTIGP 459 P + + GT GP Sbjct: 1392 KPGKDGKPGTPGP 1404 Score = 33.9 bits (76), Expect = 1.1 Identities = 20/70 (28%), Positives = 28/70 (40%), Gaps = 1/70 (1%) Query: 27 MVRPPTVMSPSGNPQLDSKFSNQGKQGGSASQSQPSPCDSKSGGHTPKALPGPGGSMGLK 86 ++ PP + P G P G +G P P K +A PGP G+ G + Sbjct: 1129 LLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQ 1188 Query: 87 NGAGN-GAKG 95 G+ GA G Sbjct: 1189 GAKGDRGAPG 1198 Score = 31.2 bits (69), Expect = 7.5 Identities = 19/70 (27%), Positives = 29/70 (41%), Gaps = 1/70 (1%) Query: 36 PSGNPQLDSKFSNQGKQGGSASQSQPSPC-DSKSGGHTPKALPGPGGSMGLKNGAGNGAK 94 P G L + +QG G S P P + G+ P+ PG G+ G+ G + Sbjct: 582 PKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGE 641 Query: 95 GKGKRERSIS 104 + E S+S Sbjct: 642 AGPRGELSVS 651 >gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo sapiens] Length = 1637 Score = 113 bits (283), Expect = 1e-24 Identities = 249/963 (25%), Positives = 327/963 (33%), Gaps = 250/963 (25%) Query: 506 GPRGVVRGPPPPYQMTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPGSQMRLPGF 565 G +GV P PP + P + P G P G HP G PG Sbjct: 628 GTQGVPGAPGPPGEAGPRGELSVSTPVPGPPG--------PPGPPGHPGPQGP----PGI 675 Query: 566 AGMINSEMEGPNVPNPASRPGLSGVSWPDDVPKIPDG-RNFPPGQGIFSGPGR-GER-FP 622 G + + P +P P PG+ G+ +P P P G + FP +G PG+ GE P Sbjct: 676 PGSLG-KCGDPGLPGPDGEPGIPGIGFPG--PPGPKGDQGFPGTKGSLGCPGKMGEPGLP 732 Query: 623 NPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPG--NNPIFPRI 680 GL E + +P G G P N S H E G P P Sbjct: 733 GKPGLPGAK-----GEPAVAMPGGPGTPGF-PGERGN-----SGEHGEIGLPGLPGLPGT 781 Query: 681 PVEGPLSPSRGDFPKGIPP--QMGPGRELEFGMVPSGMKGDVNLNVNMGSNSQMIPQKMR 738 P L RGD + PP Q PGR +E P G +G LN G Q+ R Sbjct: 782 PGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG---PRGAQGLPGLNGLKG-------QQGR 831 Query: 739 EAGAGPEEMLKLR-------PG--GSDMLPAQQ-KMVPLPFGEHPQQEYGMGPRPFLPMS 788 GP+ + PG GS +P Q +M PL +P +GP Sbjct: 832 RGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGP------- 884 Query: 789 QGPGSNS--GLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPL 846 PG + G+ IGP P P NP + P QRG Sbjct: 885 --PGEDGVIGMMGFPGAIGP-----------PGPPGNPGT---------PGQRG------ 916 Query: 847 DISVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGMLAGPAAAASIK 906 SPGI +K Q +P G+ +P PS+++ ++ K Sbjct: 917 ----------SPGIPGVKG----QRGTPGAKGEQGDKGNPG-PSEISHVIGD-------K 954 Query: 907 SPPVLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMASPAMLGNVE 966 P L A +P + +P PG+ P P G++ Sbjct: 955 GEPGLKGFAGNPGEKGNRGVPG--------------MPGLKGLKGLPGPAGPPGPRGDLG 1000 Query: 967 SGGPPPPTASQPASVNIPGSLPSSTPYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYH 1026 S G P +P IPGS M MP S Sbjct: 1001 STGNP----GEPGLRGIPGS--------------------------MGNMGMPGS----- 1025 Query: 1027 DAIKTVASSDDDSPPARSPNLPSMNNMPGMGINTQNPRIS-GPNPVVPMPTLSPMGMTQP 1085 K + A P LP ++ + G + P S G P P PT P G+ Sbjct: 1026 ---KGKRGTLGFPGRAGRPGLPGIHGLQG---DKGEPGYSEGTRPGPPGPTGDP-GLPGD 1078 Query: 1086 LSHSNQMPSPNAVGPNIP--PHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQ---- 1139 + +M P G P P G P PG G P P G +GF Sbjct: 1079 MGKKGEMGQPGPPGHLGPAGPEGAPGSPG--------SPGLPGKPG-PHGDLGFKGIKGL 1129 Query: 1140 -GFPPVQSPPQQVPFPHN-GPSG-----GQGSFPGGMGFPGEGPLGRPSNLPQSSADAAL 1192 G P ++ PP FP + GP G G+ PG G GE L R P+ + A Sbjct: 1130 LGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQG 1189 Query: 1193 CK-----PGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGATGIPEFDLSRIIPSEK-PS 1246 K PG PG P +G++ P G TGI F +P P Sbjct: 1190 AKGDRGAPGFPGLPGRKGAMGDAGPR-------------GPTGIEGFPGPPGLPGAIIPG 1236 Query: 1247 QTLQYFPRGEVPGRKQPQGPGPGFSHMQGMMGEQAPRMGLALPGMGGPGPVGTPDIPLGT 1306 QT P G P PGP SH+ G+ G++ MG PGP G P GT Sbjct: 1237 QTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKG--------SMGHPGPKGPP----GT 1284 Query: 1307 APSMPGHNPMRPPAFLQQGMMGPHHRMMSPAQSTMPG---QPTLMSNPAAAVGMIPGKDR 1363 A G MGP R+ +P +PG P P + G+ Sbjct: 1285 A-----------------GDMGPPGRLGAPGTPGLPGPRGDPGFQGFPG-----VKGEKG 1322 Query: 1364 GPA--GLYTHPGPVGSPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNP 1421 P G PGP+G G ++G G + I +P P G + GM G PG P Sbjct: 1323 NPGFLGSIGPPGPIGPKGPP-GVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPP 1381 Query: 1422 GNM 1424 GN+ Sbjct: 1382 GNL 1384 Score = 110 bits (276), Expect = 7e-24 Identities = 251/990 (25%), Positives = 332/990 (33%), Gaps = 199/990 (20%) Query: 516 PPYQMTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPGS--QMRLPGFAGMINSE- 572 P + +P PG T P+ + +P +G P +PG+ +PG AG+ + Sbjct: 99 PGFSGSPGLPGTPGNTGPYGL-VGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKG 157 Query: 573 ---MEGPNVPNPASRPGLSGVSWPDDVPKIPD--GRNFPPGQ-GIFSGPGR-GERFPNPQ 625 E + PGL G P +P P G PPG G F PG G R P Sbjct: 158 APAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGP--- 214 Query: 626 GLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIFPRIPVEGP 685 + + E+ +G ++G+ P P + + GP Sbjct: 215 -------KGHMGERVIGHKGERGVKGLTG----------------PPGPPGTVIVTLTGP 251 Query: 686 -----LSPSRGDFPKGIPPQMGPGRELEFGMVPSGMKGDVNLNVNMGSNS--------QM 732 L +GD KG + GP PSG+ G+ + GS Q Sbjct: 252 DNRTDLKGEKGD--KGAMGEPGPPG-------PSGLPGE-----SYGSEKGAPGDPGLQG 297 Query: 733 IPQKMREAGAGPEEMLKLRPG-----GSDMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPM 787 P K G E +K G G D + Q+ + P P + Y Sbjct: 298 KPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEG 357 Query: 788 SQGPGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLD 847 + GP G R + P GP P +P +P S+ L AP G K Sbjct: 358 TPGPPGPRGARGPQGPSGP-----------PGVPGSPGSSRPGLRGAPGWPGLKGSK--- 403 Query: 848 ISVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGMLAGPAAAASIKS 907 + PG + + +P GSP G SP P G P K Sbjct: 404 -----GERGRPGKDAMGTP----------GSP-GCAGSPGLPGS-PGPPGPPGDIVFRKG 446 Query: 908 PPVLGSAAASPVHLKSPSLPAPS-----PGWTSSPKPPLQSP-------------GIPPN 949 PP P +L SP +P PG + P + P GIP Sbjct: 447 PP---GDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGR 503 Query: 950 HKAPLTMASPAMLGNVESGGPP--PPTASQPASVNIPG-SLPSSTPYTMPPEPTLSQNPL 1006 A SP GN G P P P G +L +P +P L P Sbjct: 504 QGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPG 563 Query: 1007 SIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPAR-----SPNLPSMNNMPGMGINTQ 1061 + + P + D PP SP PG G + Sbjct: 564 RKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGE 623 Query: 1062 NPRISGPNPVVPMPTLSPMGMTQPLSH-SNQMPSPNAVGPNIPP-HGVPMGPGLMSHNPI 1119 P + G V P P G P S P P GP PP H P GP + + Sbjct: 624 -PGLQGTQGVPGAP--GPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGS-- 678 Query: 1120 MGHGSQEPPMVPQGRMGFPQ-GFPPVQSPPQQVPFPHNGPSGGQGSFPGGMGFPGEGPLG 1178 +G P G G P GFP P FP G G G PG MG PG G Sbjct: 679 LGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFP--GTKGSLGC-PGKMGEPGLP--G 733 Query: 1179 RPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGATGIP------ 1232 +P LP + + A+ PGGPG P GNS + E+ PG G+P Sbjct: 734 KPG-LPGAKGEPAVAMPGGPGTPGFPGERGNS-------GEHGEIGLPGLPGLPGTPGNE 785 Query: 1233 EFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQG-PG-PGFSHMQGMMGEQAPRMGLALPG 1290 D R P + Q P + G + QG PG G QG G+ P+ +PG Sbjct: 786 GLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPG 845 Query: 1291 M---GGPGPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMSPAQSTMPGQPTL 1347 + G PG G+P I PGH QG MGP Q PG P + Sbjct: 846 LDRSGFPGETGSPGI--------PGH----------QGEMGP------LGQRGYPGNPGI 881 Query: 1348 MSNPA--AAVGMI--PGK--DRGPAGLYTHPGPVGSPGM--------MMSMQGMMGPQQN 1393 + P +GM+ PG GP G PG GSPG+ +G G + N Sbjct: 882 LGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGN 941 Query: 1394 IMIPPQMRPRGMAADVGMGGFSQGPGNPGN 1423 G + G+ GF+ PG GN Sbjct: 942 PGPSEISHVIGDKGEPGLKGFAGNPGEKGN 971 Score = 107 bits (267), Expect = 8e-23 Identities = 309/1274 (24%), Positives = 408/1274 (32%), Gaps = 241/1274 (18%) Query: 290 GSPASSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGEPPTLG-ENP 348 G+PA + D G P A P P PP PP G P +G P Sbjct: 157 GAPAKEEDIELDAKGDPGLPG--APGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGP 214 Query: 349 DG-LSQEQLEHR-ERSLQTLRD--------IQRMLFPDEKEFTGAQSG-----------G 387 G + + + H+ ER ++ L I + PD + + G G Sbjct: 215 KGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274 Query: 388 PQQNPGVLDGPQKKPEGPIQAMMAQSQSLGKGPGPRTDVGAPFGPQGHRDVPFSPDEMVP 447 P PG G +K G L PG G P G +G + P M Sbjct: 275 PSGLPGESYGSEKGAPG--------DPGLQGKPGKDGVPGFP-GSEGVKGNRGFPGLMGE 325 Query: 448 PSMNSQSGTIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGP 507 + Q G IGP T E+Y+ + K ++ + Q GP Sbjct: 326 DGIKGQKGDIGPPGFRGPT-----------EYYDTYQEKGDEGTPGPPGPRGARGPQ-GP 373 Query: 508 RGVVRGPPPPYQMTPSEGWAPGGT----------EPFSDGINMPHSLPPRGMAPHPNMPG 557 G P P P APG P D + P S G A P +PG Sbjct: 374 SGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGS---PGCAGSPGLPG 430 Query: 558 S------------------QMRLPGFAGMINSE-MEGPN------------VPNPASRPG 586 S LPG+ G ++GP +P P PG Sbjct: 431 SPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPG 490 Query: 587 LSGVSWPDDVPK------IPDGRNFPPGQGIFSGPGRGERFPNPQG---LSEEMFQQQLA 637 L G+ +P + P G+ PG FP QG L E + Sbjct: 491 LPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPG----FPGAQGDPGLKGEKGETLQP 546 Query: 638 EKQLGLP--PGM-------AMEGIR--------PSMEMNRMIPGSQRHMEPGNNPIFPRI 680 E Q+G+P PG+ ++GI P + + G + P +P P Sbjct: 547 EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS 606 Query: 681 PVEGPLSPSRGDFPKGIPPQMGPGRELEFGMVPSGMKGDVNLNVNMGSNSQMIPQKMREA 740 P GP P+ P G PQ PG + G+ G G G S P Sbjct: 607 P--GPAGPAG---PPGYGPQGEPGLQGTQGV--PGAPGPPGEAGPRGELSVSTPVPGPPG 659 Query: 741 GAGPEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPMSQGPGSNSGLRNL 800 GP P G +P P P E G+ P P GP + G Sbjct: 660 PPGPPG--HPGPQGPPGIPGSLGKCGDPGLPGPDGEPGI-PGIGFPGPPGPKGDQGFPGT 716 Query: 801 REPIG-PDQRTNSRLSHMPPLPLNPSSNPTSLNTAP-----PVQRGLGRKPLDISVAG-- 852 + +G P + L P LP ++ P P +RG + +I + G Sbjct: 717 KGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLP 776 Query: 853 SQVHSPGINPLKSPTMHQVQSPMLGS---PSGNLKSPQTPSQLAGMLA-----GPAAAAS 904 +PG L P Q G P ++ P+ L G+ G Sbjct: 777 GLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTG 836 Query: 905 IKSPPVLGSAAAS--PVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMASPA-- 960 K P + S P SP +P PL G P N P + P Sbjct: 837 PKGDPGIPGLDRSGFPGETGSPGIPGHQ-----GEMGPLGQRGYPGN---PGILGPPGED 888 Query: 961 ----MLGNVESGGPPPP-----TASQPASVNIPGSLPSSTPYTMPPEPTLSQNPLSIMMS 1011 M+G + GPP P T Q S IPG E NP S Sbjct: 889 GVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP---S 945 Query: 1012 RMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMGINTQNPRISGP--- 1068 +S P +K A + + P +P + + G+ P G Sbjct: 946 EISHVIGDKGEP----GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGS 1001 Query: 1069 --NPVVP----MP-TLSPMGMTQPLSHSNQMPSPNAVG-PNIPP-HGVPMGPGLMSHNPI 1119 NP P +P ++ MGM + P G P +P HG+ G P Sbjct: 1002 TGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKG----EPG 1057 Query: 1120 MGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPSGGQGSFPGGMGFPG-EGPLG 1178 G++ P P G G P Q P H GP+G +G+ PG G PG G G Sbjct: 1058 YSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGA-PGSPGSPGLPGKPG 1116 Query: 1179 RPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGATGIP-EFDLS 1237 +L L PG G P G+ P ++ I PG G E L Sbjct: 1117 PHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGI-PGPAGEKGETGLL 1175 Query: 1238 RIIPSEKPSQTLQYFPRGEVPGRKQPQG----PG-PGFSHMQGMMGEQAPRMGLALPGMG 1292 R P PRG PG + +G PG PG +G MG+ PR + G Sbjct: 1176 RAPPG----------PRGN-PGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGF- 1223 Query: 1293 GPGPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPA 1352 PGP G P +PG Q G GP P PG P P Sbjct: 1224 -PGPPGLP------GAIIPG----------QTGNRGP------PGSRGSPGAPGPPGPPG 1260 Query: 1353 AAVGMIPGKDRGPAGLYTHPGPVGSPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMG 1412 + V I G D+G G HPGP G PG G MGP + P G D G Sbjct: 1261 SHVIGIKG-DKGSMG---HPGPKGPPGTA----GDMGPPGRLGAPGTPGLPGPRGDPGFQ 1312 Query: 1413 GFSQGPGNPGNMMF 1426 GF G GN F Sbjct: 1313 GFPGVKGEKGNPGF 1326 Score = 67.4 bits (163), Expect = 9e-11 Identities = 192/808 (23%), Positives = 260/808 (32%), Gaps = 162/808 (20%) Query: 254 LQPTPPIPAPAPKPAAPPRPLDRESPGVENKL-------IP----SVGSPASSTPLPPDG 302 L + P+P P P P P + PG+ L +P G P P PP Sbjct: 648 LSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGP 707 Query: 303 TGPNSTPNNRAVTPVSQGSNSSSADPKAPPPP--PVSSGEPPTL---GENPDGLSQEQLE 357 G P + S G +P P P P + GEP G G E+ Sbjct: 708 KGDQGFPGTKG----SLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGN 763 Query: 358 HRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQ--NPGVLDGPQKKPEGP--------IQ 407 E L + + E G P Q PG P + EGP + Sbjct: 764 SGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLN 823 Query: 408 AMMAQSQSLGKGPGPRTDVGAPFGPQGHRDVPFSPDEMVPPSMNSQSGTIGPDHLDHMTP 467 + Q GK GP+ D G P D P E P + G +GP Sbjct: 824 GLKGQQGRRGK-TGPKGDPGIP-----GLDRSGFPGETGSPGIPGHQGEMGP-------- 869 Query: 468 EQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPPPPYQM-TPSEGW 526 L Q Y + +D ++ G G + P PP TP + Sbjct: 870 -------LGQRGYPGNPG------ILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRG 916 Query: 527 APG-----------------------GTEPFSDGINMPHSLPPRGMAPHPNMPGSQMRLP 563 +PG G S I +G A +P G++ +P Sbjct: 917 SPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNR-GVP 975 Query: 564 GFAGMINSEMEGPNVPNPASRPGLSGVSWPDDVPKIPDGRNFP--------PG----QGI 611 G G+ + +P PA PG G P P R P PG +G Sbjct: 976 GMPGLKGLK----GLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGT 1031 Query: 612 FSGPGRGER--FPNPQGLSEEMFQQQLAEKQLGLPPGMAME-GIRPSM----EMNRMIPG 664 PGR R P GL + + +E PPG + G+ M EM + PG Sbjct: 1032 LGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQ--PG 1089 Query: 665 SQRHMEPGNNPIFPRIPVEGPLSPSRGDFPKGIPPQMGPGRELEFGMV-----PSGMKGD 719 H+ P P P SP G+P + GP +L F + P G++G Sbjct: 1090 PPGHLGPAG-------PEGAPGSPG----SPGLPGKPGPHGDLGFKGIKGLLGPPGIRGP 1138 Query: 720 VNLNVNMGSNSQM--IPQKMREAGAGPEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQQEY 777 L GS M + R+ GP G + +L A P + + + Sbjct: 1139 PGLPGFPGSPGPMGIRGDQGRDGIPGPAG----EKGETGLLRAPPGPRGNPGAQGAKGDR 1194 Query: 778 GMGPRPFLPMSQGPGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNPSS--NPTSLNTAP 835 G P LP +G ++G P GP + + P P P + + N P Sbjct: 1195 GAPGFPGLPGRKGAMGDAG------PRGP-----TGIEGFPGPPGLPGAIIPGQTGNRGP 1243 Query: 836 PVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGS-----PSGNLKSPQTPS 890 P RG P GS H GI K H G+ P G L +P TP Sbjct: 1244 PGSRGSPGAPGPPGPPGS--HVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPG 1301 Query: 891 QLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAP-----SPGWTSSPKPPLQSPG 945 L GP + P + +P L S P P PG P L+ Sbjct: 1302 -----LPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDP-GTLKIIS 1355 Query: 946 IPPNHKAPLTMASPAMLGNVESGGPPPP 973 +P + P T P M G E G P PP Sbjct: 1356 LPGSPGPPGTPGEPGMQG--EPGPPGPP 1381 Score = 61.2 bits (147), Expect = 7e-09 Identities = 239/999 (23%), Positives = 307/999 (30%), Gaps = 209/999 (20%) Query: 260 IPAPAPKPAAPPRPLDRESPGVENKLIPSVGSPASSTPLPPDGTGPNSTPNNRAVTPV-- 317 +P P + A D+ PG S GSP + P P G GP P + V Sbjct: 579 LPGPKGELALSGEKGDQGPPGDPG----SPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPG 634 Query: 318 ---------SQGSNSSSADPKAPPPPPVSSGEPPTLGENPDGLSQEQLEHRERSLQTLRD 368 +G S S PP PP G P G P G+ + + L Sbjct: 635 APGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQG--PPGIPGSLGKCGDPGLPG--- 689 Query: 369 IQRMLFPD-EKEFTGAQSGGPQQNPGVLDGPQKKPEGPIQAMMAQSQSLGKG--PGPRTD 425 PD E G GP G P K M + GK PG + + Sbjct: 690 ------PDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGE 743 Query: 426 --VGAPFGP-----QGHRDVPFSPDEMVPPSMNSQSGTIGPDHLDHM-----TPEQIAWL 473 V P GP G R E+ P + GT G + LD P Sbjct: 744 PAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQ 803 Query: 474 KLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPPPPYQMTPSEGWAPGGTEP 533 E R Q + Q + GP+G P P E +PG P Sbjct: 804 GPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPG--IP 861 Query: 534 FSDGINMPHSLPPRGMAPHPNMPG--------SQMRLPGFAGMINSEMEGPNVPNPASRP 585 G + P G +P PG + + GF G I GP P P P Sbjct: 862 GHQG-----EMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAI-----GP--PGPPGNP 909 Query: 586 GLSGVSWPDDVPKIPDGRNFPPGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPP 645 G G +P + R P +G G P P +S + + P Sbjct: 910 GTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGN----PGPSEISHVIGDKG--------EP 957 Query: 646 GMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIFPRIPVEGPLSPSRGDFPKGIPPQMGPGR 705 G+ P + NR +PG PG + KG+P G Sbjct: 958 GLKGFAGNPGEKGNRGVPGM-----PGLKGL------------------KGLPGPAG--- 991 Query: 706 ELEFGMVPSGMKGDVNLNVNMGS-NSQMIPQKMREAGAGPEEMLKLRPGGSDMLPAQQKM 764 P G +GD+ N G + IP M G + + G+ P + Sbjct: 992 -------PPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKR----GTLGFPGRAGR 1040 Query: 765 VPLP-----FGEHPQQEYGMGPRPFLPMSQG----PGSNSGLRNLREPIGPDQRTNSRLS 815 LP G+ + Y G RP P G PG + +P GP Sbjct: 1041 PGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQP-GPPGHLG---- 1095 Query: 816 HMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPM 875 P P P S P GL KP G + GI L P P Sbjct: 1096 -----PAGPEGAPGS-----PGSPGLPGKPGPHGDLGFK----GIKGLLGP-------PG 1134 Query: 876 LGSPSGNLKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTS 935 + P G P +P + + G I P G + + L++P P +PG Sbjct: 1135 IRGPPGLPGFPGSPGPMG--IRGDQGRDGIPGP--AGEKGETGL-LRAPPGPRGNPG-AQ 1188 Query: 936 SPKPPLQSPGIPPNHKAPLTMASPAMLGNVESGGPPPPTASQ--PASVNIPGS-LPSSTP 992 K +PG P P G + GP PT + P +PG+ +P T Sbjct: 1189 GAKGDRGAPGFP---------GLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTG 1239 Query: 993 YTMPPEPTLSQNPLSIMMSRMSKFAM-PSSTPLYH-DAIKTVASSDDDSPPARSPNLPSM 1050 PP SR S A P P H IK S P P Sbjct: 1240 NRGPPG------------SRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGD 1287 Query: 1051 NNMPGMGINTQNPRISGP-NPVVPMPTLSP--------MGMTQPLSHSNQMPSPNAVGPN 1101 PG R+ P P +P P P G + P +GP Sbjct: 1288 MGPPG--------RLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPK 1339 Query: 1102 IPPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPSGG 1161 PP GV PG + I GS PP P G G QG P PP + GP G Sbjct: 1340 GPP-GVRGDPGTL--KIISLPGSPGPPGTP-GEPGM-QGEPGPPGPPGNL-----GPCGP 1389 Query: 1162 QGSFPGGMGFPG-EGPLGRPSNLPQSSADAALCKPGGPG 1199 +G PG G PG GP G N G PG Sbjct: 1390 RGK-PGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPG 1427 Score = 54.3 bits (129), Expect = 8e-07 Identities = 80/277 (28%), Positives = 103/277 (37%), Gaps = 46/277 (16%) Query: 1161 GQGSFPGGMGFPGEGPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLG-NSMPSVFTDPD 1219 G+ FPG G PG+ P LP PG PG S V G + +P P Sbjct: 49 GEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGF--PGLPGLTGSKGVRGISGLPGFSGSPG 106 Query: 1220 LQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPGPGFSHMQGMMGE 1279 L PG TG + L +P S+ Q FP +PG G PG + ++G G Sbjct: 107 LPGT--PGNTG--PYGLVG-VPGCSGSKGEQGFP--GLPGTLGYPGI-PGAAGLKGQKGA 158 Query: 1280 QAPRMGLALPGMGGPGPVGTPDIPLGT--APSMPGH-NPMRPPAFLQ-QGMMGPHHRMMS 1335 A + L G PG G P P G P PG P PP F G MGP Sbjct: 159 PAKEEDIELDAKGDPGLPGAPG-PQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPR----- 212 Query: 1336 PAQSTMPGQPTLMSNPAAAVG--MIPGK-DRGPAGLYTHPGPVGS-------PGMMMSMQ 1385 P +G +I K +RG GL PGP G+ P ++ Sbjct: 213 --------------GPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLK 258 Query: 1386 GMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 G G + + P P G+ + G PG+PG Sbjct: 259 GEKGDKGAMGEPGPPGPSGLPGE-SYGSEKGAPGDPG 294 Score = 50.8 bits (120), Expect = 9e-06 Identities = 83/301 (27%), Positives = 113/301 (37%), Gaps = 45/301 (14%) Query: 1153 FPHNGPSGGQGSFPGGMGFPG-EGPLGRP--------------SNLPQSSADAALCKPGG 1197 FP S GQ F G G PG +GP G P S LP S L PG Sbjct: 53 FPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGL--PGT 110 Query: 1198 PGGPDSFTVLGNSMPSVFTDPDLQEVI-RPGATGIPEFDLSRIIPSEK----PSQTLQYF 1252 PG + ++G +P Q PG G P + + +K + ++ Sbjct: 111 PGNTGPYGLVG--VPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELD 168 Query: 1253 PRGE--VPGRKQPQG-PG-PGFSHMQGMMGEQAPRMGLALPGMGGP----GPVGTPDIPL 1304 +G+ +PG PQG PG PGF G +G P PG GP G +G I Sbjct: 169 AKGDPGLPGAPGPQGLPGPPGF---PGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGH 225 Query: 1305 GTAPSMPG-HNPMRPPAFLQQGMMGPHHRMMSPAQS------TMPGQPTLMSNPAAAVGM 1357 + G P PP + + GP +R + PG P P + G Sbjct: 226 KGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGS 285 Query: 1358 IPGKDRGPAGLYTHPGPVGSPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQG 1417 G G GL PG G PG S +G+ G + + + +G D+G GF +G Sbjct: 286 EKGAP-GDPGLQGKPGKDGVPGFPGS-EGVKGNRGFPGLMGEDGIKGQKGDIGPPGF-RG 342 Query: 1418 P 1418 P Sbjct: 343 P 343 Score = 50.1 bits (118), Expect = 2e-05 Identities = 99/398 (24%), Positives = 140/398 (35%), Gaps = 70/398 (17%) Query: 1047 LPSMNNMPGMGINTQNPRISGPNPVVPMPTLSPMGMTQPLSHSNQMPSPNAVGPNIPPHG 1106 LP + PG+ P +GP +V +P S + P G P G Sbjct: 98 LPGFSGSPGL---PGTPGNTGPYGLVGVPGCS--------GSKGEQGFPGLPGTLGYP-G 145 Query: 1107 VPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPSGGQGSFP 1166 +P GL ++ + +G G P G P Q P FP GP G G P Sbjct: 146 IPGAAGLKGQKGAPAK-EEDIELDAKGDPGLP-GAPGPQGLPGPPGFP--GPVGPPGP-P 200 Query: 1167 GGMGFPGE-GPLGRPSNLPQS----SADAALCKPGGPGGPDSFTVLGNSMPSVFTD---- 1217 G GFPG GP G ++ + + + GP GP ++ + P TD Sbjct: 201 GFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGE 260 Query: 1218 -PDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPGPGFSHMQGM 1276 D + PG G PS P ++ Y PG QG PG + G Sbjct: 261 KGDKGAMGEPGPPG----------PSGLPGES--YGSEKGAPGDPGLQGK-PGKDGVPGF 307 Query: 1277 MGEQAPRMGLALPGMGGPGPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMSP 1336 G + + PG+ G + +G PP F +G + Sbjct: 308 PGSEGVKGNRGFPGLMGEDGIKGQKGDIG------------PPGF--RGPTEYYDTYQEK 353 Query: 1337 AQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGL-----YTHPGPVGSPGM--MMSMQGMMG 1389 PG P P A G P GP G+ + PG G+PG + +G G Sbjct: 354 GDEGTPGPP----GPRGARG--PQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERG 407 Query: 1390 -PQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPGNMMF 1426 P ++ M P G A G+ G PG PG+++F Sbjct: 408 RPGKDAMGTPGSP--GCAGSPGLPGSPGPPGPPGDIVF 443 Score = 36.2 bits (82), Expect = 0.23 Identities = 29/90 (32%), Positives = 39/90 (43%), Gaps = 15/90 (16%) Query: 1347 LMSNPAAAVGMIPGKDRGPA---------GLYTHPGPVGSPGMM-----MSMQGMMGPQQ 1392 L + PAA+ G + KD+G G PGP GSPG + G GP+ Sbjct: 21 LAAAPAASKGCVC-KDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKG 79 Query: 1393 NIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 +P +G+ G+ GFS PG PG Sbjct: 80 FPGLPGLTGSKGVRGISGLPGFSGSPGLPG 109 Score = 35.8 bits (81), Expect = 0.30 Identities = 64/253 (25%), Positives = 83/253 (32%), Gaps = 49/253 (19%) Query: 234 LPQQPPAP-ANQDQNSSQNTRLQPT-PPIPAP--APKPAAPPRPLDRES----PGVENKL 285 L + PP P N ++ R P P +P A A P P E PG+ + Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233 Query: 286 IPSV----GSPASSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGEP 341 IP G P S P GP P + + + PK PP G P Sbjct: 1234 IPGQTGNRGPPGSRGS--PGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPP 1291 Query: 342 PTLG-ENPDGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPGVLD---- 396 LG GL + + P + F G + G + NPG L Sbjct: 1292 GRLGAPGTPGLPGPRGD-----------------PGFQGFPGVK--GEKGNPGFLGSIGP 1332 Query: 397 ----GPQKKPEGPIQAMMAQSQSLGKGPGPRTDVGAPFGPQGHRDVPFSPDEMVP----- 447 GP+ P + SL PGP G P G QG P P + P Sbjct: 1333 PGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEP-GMQGEPGPPGPPGNLGPCGPRG 1391 Query: 448 -PSMNSQSGTIGP 459 P + + GT GP Sbjct: 1392 KPGKDGKPGTPGP 1404 Score = 33.9 bits (76), Expect = 1.1 Identities = 20/70 (28%), Positives = 28/70 (40%), Gaps = 1/70 (1%) Query: 27 MVRPPTVMSPSGNPQLDSKFSNQGKQGGSASQSQPSPCDSKSGGHTPKALPGPGGSMGLK 86 ++ PP + P G P G +G P P K +A PGP G+ G + Sbjct: 1129 LLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQ 1188 Query: 87 NGAGN-GAKG 95 G+ GA G Sbjct: 1189 GAKGDRGAPG 1198 Score = 31.2 bits (69), Expect = 7.5 Identities = 19/70 (27%), Positives = 29/70 (41%), Gaps = 1/70 (1%) Query: 36 PSGNPQLDSKFSNQGKQGGSASQSQPSPC-DSKSGGHTPKALPGPGGSMGLKNGAGNGAK 94 P G L + +QG G S P P + G+ P+ PG G+ G+ G + Sbjct: 582 PKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGE 641 Query: 95 GKGKRERSIS 104 + E S+S Sbjct: 642 AGPRGELSVS 651 >gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo sapiens] Length = 1670 Score = 113 bits (283), Expect = 1e-24 Identities = 249/963 (25%), Positives = 327/963 (33%), Gaps = 250/963 (25%) Query: 506 GPRGVVRGPPPPYQMTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPGSQMRLPGF 565 G +GV P PP + P + P G P G HP G PG Sbjct: 628 GTQGVPGAPGPPGEAGPRGELSVSTPVPGPPG--------PPGPPGHPGPQGP----PGI 675 Query: 566 AGMINSEMEGPNVPNPASRPGLSGVSWPDDVPKIPDG-RNFPPGQGIFSGPGR-GER-FP 622 G + + P +P P PG+ G+ +P P P G + FP +G PG+ GE P Sbjct: 676 PGSLG-KCGDPGLPGPDGEPGIPGIGFPG--PPGPKGDQGFPGTKGSLGCPGKMGEPGLP 732 Query: 623 NPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPG--NNPIFPRI 680 GL E + +P G G P N S H E G P P Sbjct: 733 GKPGLPGAK-----GEPAVAMPGGPGTPGF-PGERGN-----SGEHGEIGLPGLPGLPGT 781 Query: 681 PVEGPLSPSRGDFPKGIPP--QMGPGRELEFGMVPSGMKGDVNLNVNMGSNSQMIPQKMR 738 P L RGD + PP Q PGR +E P G +G LN G Q+ R Sbjct: 782 PGNEGLDGPRGDPGQPGPPGEQGPPGRCIEG---PRGAQGLPGLNGLKG-------QQGR 831 Query: 739 EAGAGPEEMLKLR-------PG--GSDMLPAQQ-KMVPLPFGEHPQQEYGMGPRPFLPMS 788 GP+ + PG GS +P Q +M PL +P +GP Sbjct: 832 RGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGP------- 884 Query: 789 QGPGSNS--GLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPL 846 PG + G+ IGP P P NP + P QRG Sbjct: 885 --PGEDGVIGMMGFPGAIGP-----------PGPPGNPGT---------PGQRG------ 916 Query: 847 DISVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGMLAGPAAAASIK 906 SPGI +K Q +P G+ +P PS+++ ++ K Sbjct: 917 ----------SPGIPGVKG----QRGTPGAKGEQGDKGNPG-PSEISHVIGD-------K 954 Query: 907 SPPVLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMASPAMLGNVE 966 P L A +P + +P PG+ P P G++ Sbjct: 955 GEPGLKGFAGNPGEKGNRGVPG--------------MPGLKGLKGLPGPAGPPGPRGDLG 1000 Query: 967 SGGPPPPTASQPASVNIPGSLPSSTPYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYH 1026 S G P +P IPGS M MP S Sbjct: 1001 STGNP----GEPGLRGIPGS--------------------------MGNMGMPGS----- 1025 Query: 1027 DAIKTVASSDDDSPPARSPNLPSMNNMPGMGINTQNPRIS-GPNPVVPMPTLSPMGMTQP 1085 K + A P LP ++ + G + P S G P P PT P G+ Sbjct: 1026 ---KGKRGTLGFPGRAGRPGLPGIHGLQG---DKGEPGYSEGTRPGPPGPTGDP-GLPGD 1078 Query: 1086 LSHSNQMPSPNAVGPNIP--PHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQ---- 1139 + +M P G P P G P PG G P P G +GF Sbjct: 1079 MGKKGEMGQPGPPGHLGPAGPEGAPGSPG--------SPGLPGKPG-PHGDLGFKGIKGL 1129 Query: 1140 -GFPPVQSPPQQVPFPHN-GPSG-----GQGSFPGGMGFPGEGPLGRPSNLPQSSADAAL 1192 G P ++ PP FP + GP G G+ PG G GE L R P+ + A Sbjct: 1130 LGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQG 1189 Query: 1193 CK-----PGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGATGIPEFDLSRIIPSEK-PS 1246 K PG PG P +G++ P G TGI F +P P Sbjct: 1190 AKGDRGAPGFPGLPGRKGAMGDAGPR-------------GPTGIEGFPGPPGLPGAIIPG 1236 Query: 1247 QTLQYFPRGEVPGRKQPQGPGPGFSHMQGMMGEQAPRMGLALPGMGGPGPVGTPDIPLGT 1306 QT P G P PGP SH+ G+ G++ MG PGP G P GT Sbjct: 1237 QTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKG--------SMGHPGPKGPP----GT 1284 Query: 1307 APSMPGHNPMRPPAFLQQGMMGPHHRMMSPAQSTMPG---QPTLMSNPAAAVGMIPGKDR 1363 A G MGP R+ +P +PG P P + G+ Sbjct: 1285 A-----------------GDMGPPGRLGAPGTPGLPGPRGDPGFQGFPG-----VKGEKG 1322 Query: 1364 GPA--GLYTHPGPVGSPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNP 1421 P G PGP+G G ++G G + I +P P G + GM G PG P Sbjct: 1323 NPGFLGSIGPPGPIGPKGPP-GVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPP 1381 Query: 1422 GNM 1424 GN+ Sbjct: 1382 GNL 1384 Score = 110 bits (276), Expect = 7e-24 Identities = 251/990 (25%), Positives = 332/990 (33%), Gaps = 199/990 (20%) Query: 516 PPYQMTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPGS--QMRLPGFAGMINSE- 572 P + +P PG T P+ + +P +G P +PG+ +PG AG+ + Sbjct: 99 PGFSGSPGLPGTPGNTGPYGL-VGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKG 157 Query: 573 ---MEGPNVPNPASRPGLSGVSWPDDVPKIPD--GRNFPPGQ-GIFSGPGR-GERFPNPQ 625 E + PGL G P +P P G PPG G F PG G R P Sbjct: 158 APAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGP--- 214 Query: 626 GLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIFPRIPVEGP 685 + + E+ +G ++G+ P P + + GP Sbjct: 215 -------KGHMGERVIGHKGERGVKGLTG----------------PPGPPGTVIVTLTGP 251 Query: 686 -----LSPSRGDFPKGIPPQMGPGRELEFGMVPSGMKGDVNLNVNMGSNS--------QM 732 L +GD KG + GP PSG+ G+ + GS Q Sbjct: 252 DNRTDLKGEKGD--KGAMGEPGPPG-------PSGLPGE-----SYGSEKGAPGDPGLQG 297 Query: 733 IPQKMREAGAGPEEMLKLRPG-----GSDMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPM 787 P K G E +K G G D + Q+ + P P + Y Sbjct: 298 KPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEG 357 Query: 788 SQGPGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLD 847 + GP G R + P GP P +P +P S+ L AP G K Sbjct: 358 TPGPPGPRGARGPQGPSGP-----------PGVPGSPGSSRPGLRGAPGWPGLKGSK--- 403 Query: 848 ISVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGMLAGPAAAASIKS 907 + PG + + +P GSP G SP P G P K Sbjct: 404 -----GERGRPGKDAMGTP----------GSP-GCAGSPGLPGS-PGPPGPPGDIVFRKG 446 Query: 908 PPVLGSAAASPVHLKSPSLPAPS-----PGWTSSPKPPLQSP-------------GIPPN 949 PP P +L SP +P PG + P + P GIP Sbjct: 447 PP---GDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGR 503 Query: 950 HKAPLTMASPAMLGNVESGGPP--PPTASQPASVNIPG-SLPSSTPYTMPPEPTLSQNPL 1006 A SP GN G P P P G +L +P +P L P Sbjct: 504 QGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPG 563 Query: 1007 SIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPAR-----SPNLPSMNNMPGMGINTQ 1061 + + P + D PP SP PG G + Sbjct: 564 RKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGE 623 Query: 1062 NPRISGPNPVVPMPTLSPMGMTQPLSH-SNQMPSPNAVGPNIPP-HGVPMGPGLMSHNPI 1119 P + G V P P G P S P P GP PP H P GP + + Sbjct: 624 -PGLQGTQGVPGAP--GPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGS-- 678 Query: 1120 MGHGSQEPPMVPQGRMGFPQ-GFPPVQSPPQQVPFPHNGPSGGQGSFPGGMGFPGEGPLG 1178 +G P G G P GFP P FP G G G PG MG PG G Sbjct: 679 LGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFP--GTKGSLGC-PGKMGEPGLP--G 733 Query: 1179 RPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGATGIP------ 1232 +P LP + + A+ PGGPG P GNS + E+ PG G+P Sbjct: 734 KPG-LPGAKGEPAVAMPGGPGTPGFPGERGNS-------GEHGEIGLPGLPGLPGTPGNE 785 Query: 1233 EFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQG-PG-PGFSHMQGMMGEQAPRMGLALPG 1290 D R P + Q P + G + QG PG G QG G+ P+ +PG Sbjct: 786 GLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPG 845 Query: 1291 M---GGPGPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMSPAQSTMPGQPTL 1347 + G PG G+P I PGH QG MGP Q PG P + Sbjct: 846 LDRSGFPGETGSPGI--------PGH----------QGEMGP------LGQRGYPGNPGI 881 Query: 1348 MSNPA--AAVGMI--PGK--DRGPAGLYTHPGPVGSPGM--------MMSMQGMMGPQQN 1393 + P +GM+ PG GP G PG GSPG+ +G G + N Sbjct: 882 LGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGN 941 Query: 1394 IMIPPQMRPRGMAADVGMGGFSQGPGNPGN 1423 G + G+ GF+ PG GN Sbjct: 942 PGPSEISHVIGDKGEPGLKGFAGNPGEKGN 971 Score = 107 bits (267), Expect = 8e-23 Identities = 309/1274 (24%), Positives = 408/1274 (32%), Gaps = 241/1274 (18%) Query: 290 GSPASSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGEPPTLG-ENP 348 G+PA + D G P A P P PP PP G P +G P Sbjct: 157 GAPAKEEDIELDAKGDPGLPG--APGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGP 214 Query: 349 DG-LSQEQLEHR-ERSLQTLRD--------IQRMLFPDEKEFTGAQSG-----------G 387 G + + + H+ ER ++ L I + PD + + G G Sbjct: 215 KGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPG 274 Query: 388 PQQNPGVLDGPQKKPEGPIQAMMAQSQSLGKGPGPRTDVGAPFGPQGHRDVPFSPDEMVP 447 P PG G +K G L PG G P G +G + P M Sbjct: 275 PSGLPGESYGSEKGAPG--------DPGLQGKPGKDGVPGFP-GSEGVKGNRGFPGLMGE 325 Query: 448 PSMNSQSGTIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGP 507 + Q G IGP T E+Y+ + K ++ + Q GP Sbjct: 326 DGIKGQKGDIGPPGFRGPT-----------EYYDTYQEKGDEGTPGPPGPRGARGPQ-GP 373 Query: 508 RGVVRGPPPPYQMTPSEGWAPGGT----------EPFSDGINMPHSLPPRGMAPHPNMPG 557 G P P P APG P D + P S G A P +PG Sbjct: 374 SGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGS---PGCAGSPGLPG 430 Query: 558 S------------------QMRLPGFAGMINSE-MEGPN------------VPNPASRPG 586 S LPG+ G ++GP +P P PG Sbjct: 431 SPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPG 490 Query: 587 LSGVSWPDDVPK------IPDGRNFPPGQGIFSGPGRGERFPNPQG---LSEEMFQQQLA 637 L G+ +P + P G+ PG FP QG L E + Sbjct: 491 LPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPG----FPGAQGDPGLKGEKGETLQP 546 Query: 638 EKQLGLP--PGM-------AMEGIR--------PSMEMNRMIPGSQRHMEPGNNPIFPRI 680 E Q+G+P PG+ ++GI P + + G + P +P P Sbjct: 547 EGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGS 606 Query: 681 PVEGPLSPSRGDFPKGIPPQMGPGRELEFGMVPSGMKGDVNLNVNMGSNSQMIPQKMREA 740 P GP P+ P G PQ PG + G+ G G G S P Sbjct: 607 P--GPAGPAG---PPGYGPQGEPGLQGTQGV--PGAPGPPGEAGPRGELSVSTPVPGPPG 659 Query: 741 GAGPEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPMSQGPGSNSGLRNL 800 GP P G +P P P E G+ P P GP + G Sbjct: 660 PPGPPG--HPGPQGPPGIPGSLGKCGDPGLPGPDGEPGI-PGIGFPGPPGPKGDQGFPGT 716 Query: 801 REPIG-PDQRTNSRLSHMPPLPLNPSSNPTSLNTAP-----PVQRGLGRKPLDISVAG-- 852 + +G P + L P LP ++ P P +RG + +I + G Sbjct: 717 KGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLP 776 Query: 853 SQVHSPGINPLKSPTMHQVQSPMLGS---PSGNLKSPQTPSQLAGMLA-----GPAAAAS 904 +PG L P Q G P ++ P+ L G+ G Sbjct: 777 GLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTG 836 Query: 905 IKSPPVLGSAAAS--PVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMASPA-- 960 K P + S P SP +P PL G P N P + P Sbjct: 837 PKGDPGIPGLDRSGFPGETGSPGIPGHQ-----GEMGPLGQRGYPGN---PGILGPPGED 888 Query: 961 ----MLGNVESGGPPPP-----TASQPASVNIPGSLPSSTPYTMPPEPTLSQNPLSIMMS 1011 M+G + GPP P T Q S IPG E NP S Sbjct: 889 GVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGP---S 945 Query: 1012 RMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMGINTQNPRISGP--- 1068 +S P +K A + + P +P + + G+ P G Sbjct: 946 EISHVIGDKGEP----GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGS 1001 Query: 1069 --NPVVP----MP-TLSPMGMTQPLSHSNQMPSPNAVG-PNIPP-HGVPMGPGLMSHNPI 1119 NP P +P ++ MGM + P G P +P HG+ G P Sbjct: 1002 TGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKG----EPG 1057 Query: 1120 MGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPSGGQGSFPGGMGFPG-EGPLG 1178 G++ P P G G P Q P H GP+G +G+ PG G PG G G Sbjct: 1058 YSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGA-PGSPGSPGLPGKPG 1116 Query: 1179 RPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGATGIP-EFDLS 1237 +L L PG G P G+ P ++ I PG G E L Sbjct: 1117 PHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGI-PGPAGEKGETGLL 1175 Query: 1238 RIIPSEKPSQTLQYFPRGEVPGRKQPQG----PG-PGFSHMQGMMGEQAPRMGLALPGMG 1292 R P PRG PG + +G PG PG +G MG+ PR + G Sbjct: 1176 RAPPG----------PRGN-PGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGF- 1223 Query: 1293 GPGPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPA 1352 PGP G P +PG Q G GP P PG P P Sbjct: 1224 -PGPPGLP------GAIIPG----------QTGNRGP------PGSRGSPGAPGPPGPPG 1260 Query: 1353 AAVGMIPGKDRGPAGLYTHPGPVGSPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMG 1412 + V I G D+G G HPGP G PG G MGP + P G D G Sbjct: 1261 SHVIGIKG-DKGSMG---HPGPKGPPGTA----GDMGPPGRLGAPGTPGLPGPRGDPGFQ 1312 Query: 1413 GFSQGPGNPGNMMF 1426 GF G GN F Sbjct: 1313 GFPGVKGEKGNPGF 1326 Score = 67.4 bits (163), Expect = 9e-11 Identities = 192/808 (23%), Positives = 260/808 (32%), Gaps = 162/808 (20%) Query: 254 LQPTPPIPAPAPKPAAPPRPLDRESPGVENKL-------IP----SVGSPASSTPLPPDG 302 L + P+P P P P P + PG+ L +P G P P PP Sbjct: 648 LSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGP 707 Query: 303 TGPNSTPNNRAVTPVSQGSNSSSADPKAPPPP--PVSSGEPPTL---GENPDGLSQEQLE 357 G P + S G +P P P P + GEP G G E+ Sbjct: 708 KGDQGFPGTKG----SLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGN 763 Query: 358 HRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQ--NPGVLDGPQKKPEGP--------IQ 407 E L + + E G P Q PG P + EGP + Sbjct: 764 SGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLN 823 Query: 408 AMMAQSQSLGKGPGPRTDVGAPFGPQGHRDVPFSPDEMVPPSMNSQSGTIGPDHLDHMTP 467 + Q GK GP+ D G P D P E P + G +GP Sbjct: 824 GLKGQQGRRGK-TGPKGDPGIP-----GLDRSGFPGETGSPGIPGHQGEMGP-------- 869 Query: 468 EQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPPPPYQM-TPSEGW 526 L Q Y + +D ++ G G + P PP TP + Sbjct: 870 -------LGQRGYPGNPG------ILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRG 916 Query: 527 APG-----------------------GTEPFSDGINMPHSLPPRGMAPHPNMPGSQMRLP 563 +PG G S I +G A +P G++ +P Sbjct: 917 SPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNR-GVP 975 Query: 564 GFAGMINSEMEGPNVPNPASRPGLSGVSWPDDVPKIPDGRNFP--------PG----QGI 611 G G+ + +P PA PG G P P R P PG +G Sbjct: 976 GMPGLKGLK----GLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGT 1031 Query: 612 FSGPGRGER--FPNPQGLSEEMFQQQLAEKQLGLPPGMAME-GIRPSM----EMNRMIPG 664 PGR R P GL + + +E PPG + G+ M EM + PG Sbjct: 1032 LGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQ--PG 1089 Query: 665 SQRHMEPGNNPIFPRIPVEGPLSPSRGDFPKGIPPQMGPGRELEFGMV-----PSGMKGD 719 H+ P P P SP G+P + GP +L F + P G++G Sbjct: 1090 PPGHLGPAG-------PEGAPGSPG----SPGLPGKPGPHGDLGFKGIKGLLGPPGIRGP 1138 Query: 720 VNLNVNMGSNSQM--IPQKMREAGAGPEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQQEY 777 L GS M + R+ GP G + +L A P + + + Sbjct: 1139 PGLPGFPGSPGPMGIRGDQGRDGIPGPAG----EKGETGLLRAPPGPRGNPGAQGAKGDR 1194 Query: 778 GMGPRPFLPMSQGPGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNPSS--NPTSLNTAP 835 G P LP +G ++G P GP + + P P P + + N P Sbjct: 1195 GAPGFPGLPGRKGAMGDAG------PRGP-----TGIEGFPGPPGLPGAIIPGQTGNRGP 1243 Query: 836 PVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGS-----PSGNLKSPQTPS 890 P RG P GS H GI K H G+ P G L +P TP Sbjct: 1244 PGSRGSPGAPGPPGPPGS--HVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPG 1301 Query: 891 QLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAP-----SPGWTSSPKPPLQSPG 945 L GP + P + +P L S P P PG P L+ Sbjct: 1302 -----LPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDP-GTLKIIS 1355 Query: 946 IPPNHKAPLTMASPAMLGNVESGGPPPP 973 +P + P T P M G E G P PP Sbjct: 1356 LPGSPGPPGTPGEPGMQG--EPGPPGPP 1381 Score = 61.2 bits (147), Expect = 7e-09 Identities = 239/999 (23%), Positives = 307/999 (30%), Gaps = 209/999 (20%) Query: 260 IPAPAPKPAAPPRPLDRESPGVENKLIPSVGSPASSTPLPPDGTGPNSTPNNRAVTPV-- 317 +P P + A D+ PG S GSP + P P G GP P + V Sbjct: 579 LPGPKGELALSGEKGDQGPPGDPG----SPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPG 634 Query: 318 ---------SQGSNSSSADPKAPPPPPVSSGEPPTLGENPDGLSQEQLEHRERSLQTLRD 368 +G S S PP PP G P G P G+ + + L Sbjct: 635 APGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQG--PPGIPGSLGKCGDPGLPG--- 689 Query: 369 IQRMLFPD-EKEFTGAQSGGPQQNPGVLDGPQKKPEGPIQAMMAQSQSLGKG--PGPRTD 425 PD E G GP G P K M + GK PG + + Sbjct: 690 ------PDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGE 743 Query: 426 --VGAPFGP-----QGHRDVPFSPDEMVPPSMNSQSGTIGPDHLDHM-----TPEQIAWL 473 V P GP G R E+ P + GT G + LD P Sbjct: 744 PAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQ 803 Query: 474 KLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPPPPYQMTPSEGWAPGGTEP 533 E R Q + Q + GP+G P P E +PG P Sbjct: 804 GPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPG--IP 861 Query: 534 FSDGINMPHSLPPRGMAPHPNMPG--------SQMRLPGFAGMINSEMEGPNVPNPASRP 585 G + P G +P PG + + GF G I GP P P P Sbjct: 862 GHQG-----EMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAI-----GP--PGPPGNP 909 Query: 586 GLSGVSWPDDVPKIPDGRNFPPGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPP 645 G G +P + R P +G G P P +S + + P Sbjct: 910 GTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGN----PGPSEISHVIGDKG--------EP 957 Query: 646 GMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIFPRIPVEGPLSPSRGDFPKGIPPQMGPGR 705 G+ P + NR +PG PG + KG+P G Sbjct: 958 GLKGFAGNPGEKGNRGVPGM-----PGLKGL------------------KGLPGPAG--- 991 Query: 706 ELEFGMVPSGMKGDVNLNVNMGS-NSQMIPQKMREAGAGPEEMLKLRPGGSDMLPAQQKM 764 P G +GD+ N G + IP M G + + G+ P + Sbjct: 992 -------PPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKR----GTLGFPGRAGR 1040 Query: 765 VPLP-----FGEHPQQEYGMGPRPFLPMSQG----PGSNSGLRNLREPIGPDQRTNSRLS 815 LP G+ + Y G RP P G PG + +P GP Sbjct: 1041 PGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQP-GPPGHLG---- 1095 Query: 816 HMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPM 875 P P P S P GL KP G + GI L P P Sbjct: 1096 -----PAGPEGAPGS-----PGSPGLPGKPGPHGDLGFK----GIKGLLGP-------PG 1134 Query: 876 LGSPSGNLKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTS 935 + P G P +P + + G I P G + + L++P P +PG Sbjct: 1135 IRGPPGLPGFPGSPGPMG--IRGDQGRDGIPGP--AGEKGETGL-LRAPPGPRGNPG-AQ 1188 Query: 936 SPKPPLQSPGIPPNHKAPLTMASPAMLGNVESGGPPPPTASQ--PASVNIPGS-LPSSTP 992 K +PG P P G + GP PT + P +PG+ +P T Sbjct: 1189 GAKGDRGAPGFP---------GLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTG 1239 Query: 993 YTMPPEPTLSQNPLSIMMSRMSKFAM-PSSTPLYH-DAIKTVASSDDDSPPARSPNLPSM 1050 PP SR S A P P H IK S P P Sbjct: 1240 NRGPPG------------SRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGD 1287 Query: 1051 NNMPGMGINTQNPRISGP-NPVVPMPTLSP--------MGMTQPLSHSNQMPSPNAVGPN 1101 PG R+ P P +P P P G + P +GP Sbjct: 1288 MGPPG--------RLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPK 1339 Query: 1102 IPPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPSGG 1161 PP GV PG + I GS PP P G G QG P PP + GP G Sbjct: 1340 GPP-GVRGDPGTL--KIISLPGSPGPPGTP-GEPGM-QGEPGPPGPPGNL-----GPCGP 1389 Query: 1162 QGSFPGGMGFPG-EGPLGRPSNLPQSSADAALCKPGGPG 1199 +G PG G PG GP G N G PG Sbjct: 1390 RGK-PGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPG 1427 Score = 54.3 bits (129), Expect = 8e-07 Identities = 80/277 (28%), Positives = 103/277 (37%), Gaps = 46/277 (16%) Query: 1161 GQGSFPGGMGFPGEGPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLG-NSMPSVFTDPD 1219 G+ FPG G PG+ P LP PG PG S V G + +P P Sbjct: 49 GEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGF--PGLPGLTGSKGVRGISGLPGFSGSPG 106 Query: 1220 LQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPGPGFSHMQGMMGE 1279 L PG TG + L +P S+ Q FP +PG G PG + ++G G Sbjct: 107 LPGT--PGNTG--PYGLVG-VPGCSGSKGEQGFP--GLPGTLGYPGI-PGAAGLKGQKGA 158 Query: 1280 QAPRMGLALPGMGGPGPVGTPDIPLGT--APSMPGH-NPMRPPAFLQ-QGMMGPHHRMMS 1335 A + L G PG G P P G P PG P PP F G MGP Sbjct: 159 PAKEEDIELDAKGDPGLPGAPG-PQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPR----- 212 Query: 1336 PAQSTMPGQPTLMSNPAAAVG--MIPGK-DRGPAGLYTHPGPVGS-------PGMMMSMQ 1385 P +G +I K +RG GL PGP G+ P ++ Sbjct: 213 --------------GPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLK 258 Query: 1386 GMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 G G + + P P G+ + G PG+PG Sbjct: 259 GEKGDKGAMGEPGPPGPSGLPGE-SYGSEKGAPGDPG 294 Score = 50.8 bits (120), Expect = 9e-06 Identities = 83/301 (27%), Positives = 113/301 (37%), Gaps = 45/301 (14%) Query: 1153 FPHNGPSGGQGSFPGGMGFPG-EGPLGRP--------------SNLPQSSADAALCKPGG 1197 FP S GQ F G G PG +GP G P S LP S L PG Sbjct: 53 FPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGL--PGT 110 Query: 1198 PGGPDSFTVLGNSMPSVFTDPDLQEVI-RPGATGIPEFDLSRIIPSEK----PSQTLQYF 1252 PG + ++G +P Q PG G P + + +K + ++ Sbjct: 111 PGNTGPYGLVG--VPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELD 168 Query: 1253 PRGE--VPGRKQPQG-PG-PGFSHMQGMMGEQAPRMGLALPGMGGP----GPVGTPDIPL 1304 +G+ +PG PQG PG PGF G +G P PG GP G +G I Sbjct: 169 AKGDPGLPGAPGPQGLPGPPGF---PGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGH 225 Query: 1305 GTAPSMPG-HNPMRPPAFLQQGMMGPHHRMMSPAQS------TMPGQPTLMSNPAAAVGM 1357 + G P PP + + GP +R + PG P P + G Sbjct: 226 KGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGS 285 Query: 1358 IPGKDRGPAGLYTHPGPVGSPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQG 1417 G G GL PG G PG S +G+ G + + + +G D+G GF +G Sbjct: 286 EKGAP-GDPGLQGKPGKDGVPGFPGS-EGVKGNRGFPGLMGEDGIKGQKGDIGPPGF-RG 342 Query: 1418 P 1418 P Sbjct: 343 P 343 Score = 50.1 bits (118), Expect = 2e-05 Identities = 99/398 (24%), Positives = 140/398 (35%), Gaps = 70/398 (17%) Query: 1047 LPSMNNMPGMGINTQNPRISGPNPVVPMPTLSPMGMTQPLSHSNQMPSPNAVGPNIPPHG 1106 LP + PG+ P +GP +V +P S + P G P G Sbjct: 98 LPGFSGSPGL---PGTPGNTGPYGLVGVPGCS--------GSKGEQGFPGLPGTLGYP-G 145 Query: 1107 VPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPSGGQGSFP 1166 +P GL ++ + +G G P G P Q P FP GP G G P Sbjct: 146 IPGAAGLKGQKGAPAK-EEDIELDAKGDPGLP-GAPGPQGLPGPPGFP--GPVGPPGP-P 200 Query: 1167 GGMGFPGE-GPLGRPSNLPQS----SADAALCKPGGPGGPDSFTVLGNSMPSVFTD---- 1217 G GFPG GP G ++ + + + GP GP ++ + P TD Sbjct: 201 GFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGE 260 Query: 1218 -PDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPGPGFSHMQGM 1276 D + PG G PS P ++ Y PG QG PG + G Sbjct: 261 KGDKGAMGEPGPPG----------PSGLPGES--YGSEKGAPGDPGLQGK-PGKDGVPGF 307 Query: 1277 MGEQAPRMGLALPGMGGPGPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMSP 1336 G + + PG+ G + +G PP F +G + Sbjct: 308 PGSEGVKGNRGFPGLMGEDGIKGQKGDIG------------PPGF--RGPTEYYDTYQEK 353 Query: 1337 AQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGL-----YTHPGPVGSPGM--MMSMQGMMG 1389 PG P P A G P GP G+ + PG G+PG + +G G Sbjct: 354 GDEGTPGPP----GPRGARG--PQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERG 407 Query: 1390 -PQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPGNMMF 1426 P ++ M P G A G+ G PG PG+++F Sbjct: 408 RPGKDAMGTPGSP--GCAGSPGLPGSPGPPGPPGDIVF 443 Score = 36.2 bits (82), Expect = 0.23 Identities = 29/90 (32%), Positives = 39/90 (43%), Gaps = 15/90 (16%) Query: 1347 LMSNPAAAVGMIPGKDRGPA---------GLYTHPGPVGSPGMM-----MSMQGMMGPQQ 1392 L + PAA+ G + KD+G G PGP GSPG + G GP+ Sbjct: 21 LAAAPAASKGCVC-KDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKG 79 Query: 1393 NIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 +P +G+ G+ GFS PG PG Sbjct: 80 FPGLPGLTGSKGVRGISGLPGFSGSPGLPG 109 Score = 35.8 bits (81), Expect = 0.30 Identities = 64/253 (25%), Positives = 83/253 (32%), Gaps = 49/253 (19%) Query: 234 LPQQPPAP-ANQDQNSSQNTRLQPT-PPIPAP--APKPAAPPRPLDRES----PGVENKL 285 L + PP P N ++ R P P +P A A P P E PG+ + Sbjct: 1174 LLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAI 1233 Query: 286 IPSV----GSPASSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGEP 341 IP G P S P GP P + + + PK PP G P Sbjct: 1234 IPGQTGNRGPPGSRGS--PGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPP 1291 Query: 342 PTLG-ENPDGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPGVLD---- 396 LG GL + + P + F G + G + NPG L Sbjct: 1292 GRLGAPGTPGLPGPRGD-----------------PGFQGFPGVK--GEKGNPGFLGSIGP 1332 Query: 397 ----GPQKKPEGPIQAMMAQSQSLGKGPGPRTDVGAPFGPQGHRDVPFSPDEMVP----- 447 GP+ P + SL PGP G P G QG P P + P Sbjct: 1333 PGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEP-GMQGEPGPPGPPGNLGPCGPRG 1391 Query: 448 -PSMNSQSGTIGP 459 P + + GT GP Sbjct: 1392 KPGKDGKPGTPGP 1404 Score = 33.9 bits (76), Expect = 1.1 Identities = 20/70 (28%), Positives = 28/70 (40%), Gaps = 1/70 (1%) Query: 27 MVRPPTVMSPSGNPQLDSKFSNQGKQGGSASQSQPSPCDSKSGGHTPKALPGPGGSMGLK 86 ++ PP + P G P G +G P P K +A PGP G+ G + Sbjct: 1129 LLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQ 1188 Query: 87 NGAGN-GAKG 95 G+ GA G Sbjct: 1189 GAKGDRGAPG 1198 Score = 31.2 bits (69), Expect = 7.5 Identities = 19/70 (27%), Positives = 29/70 (41%), Gaps = 1/70 (1%) Query: 36 PSGNPQLDSKFSNQGKQGGSASQSQPSPC-DSKSGGHTPKALPGPGGSMGLKNGAGNGAK 94 P G L + +QG G S P P + G+ P+ PG G+ G+ G + Sbjct: 582 PKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGE 641 Query: 95 GKGKRERSIS 104 + E S+S Sbjct: 642 AGPRGELSVS 651 >gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] Length = 1690 Score = 112 bits (281), Expect = 2e-24 Identities = 311/1246 (24%), Positives = 415/1246 (33%), Gaps = 303/1246 (24%) Query: 258 PPIPAPAP-KPAAPPRPLDRESPGVE-----NKLIPSVGSPA----SSTPLPPDGTGPNS 307 P P AP KP P P +PG++ + + SVG+P PP G GP Sbjct: 425 PGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGRGPKG 484 Query: 308 TPNNRAVT---------------PVSQGSNSSSADP-----KAPPPPPVSSGEPPTLGEN 347 N + P QGS P K P PP + G P G++ Sbjct: 485 EKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKH 544 Query: 348 -PDGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPGVLDGPQKKPEGPI 406 G + + + ++ + PD Q G ++ + P G Sbjct: 545 GASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDH 604 Query: 407 QAMMAQSQSLGKG-PGPRTDVG--APFGPQGHRDVPFSPDEMVPPSMNSQSGTIGPDHLD 463 + + GKG PGP G P GP G P P E P + G GPD L Sbjct: 605 E----DATPGGKGFPGPLGPPGKAGPVGPPG-LGFPGPPGERGHPGVPGHPGVRGPDGLK 659 Query: 464 HMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPPPPYQMTPS 523 + I+ C++ +HGP G GPP P Sbjct: 660 GQKGDTIS-----------------------CNVT--YPGRHGPPGF-DGPPGPKGFPGP 693 Query: 524 EGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPG--SQMRLPGFAGMINSEMEGPNVPNP 581 +G APG + SDG P G A P PG M PGF G S GP P P Sbjct: 694 QG-APGLSG--SDGHKGRPGTP--GTAEIPGPPGFRGDMGDPGFGGEKGSSPVGP--PGP 746 Query: 582 ASRPGLSGVSWPDDVPKIPDGRNFPPGQGIFSG-PG----RGERFPNPQGLSEEMFQQQL 636 PG++G P G PPG+ SG PG RG+ P G Sbjct: 747 PGSPGVNGQKGIPGDPAF--GHLGPPGKRGLSGVPGIKGPRGD--PGCPG---------- 792 Query: 637 AEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIFPRIPVEGPLSPSRGDFPKG 696 AE G+P + ++G + G + H FP +P GP S G Sbjct: 793 AEGPAGIPGFLGLKGPK----------GREGHAG------FPGVP--GPPGHSCERGAPG 834 Query: 697 IPPQMG-PGRELEFGMVPS-GMKGDVNLNVNMGSNSQMIPQKMREAGAGPEEMLKLRPGG 754 IP Q G PG G G GDV GP P G Sbjct: 835 IPGQPGLPGYPGSPGAPGGKGQPGDV----------------------GPPG-----PAG 867 Query: 755 SDMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPMSQGPGSNSGLRNLREPIGPDQRTNSRL 814 LP +P G H GP P LP GP + GL P GP R Sbjct: 868 MKGLPG----LPGRPGAH-------GP-PGLPGIPGPFGDDGLPGPPGPKGP--RGLPGF 913 Query: 815 SHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLDISVAGSQ--VHSPGINPLKSPTMHQVQ 872 P P + P ++G+ P D + G++ + PG + + + Q Sbjct: 914 PGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPG-DEGEMAIISQKG 972 Query: 873 SPMLGSPSGNLKSP-QTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAP-S 930 +P P G+ P + + + G PP G P P P P Sbjct: 973 TPGEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPP--GFHRGEPGEKGQPGPPGPPG 1030 Query: 931 PGWTSSPKPPLQSPGIPPNHKAPLTMASPAMLGNVESGGP------------PPPTASQP 978 P ++ + + PG+P + P + P G + GP PP +P Sbjct: 1031 PPGSTGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPGPKGEP 1090 Query: 979 ASVNIPGSLPSSTPYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDD 1038 S PG +S +P Q P S Sbjct: 1091 GSPGCPGHFGASGEQGLPG----IQGPRG--------------------------SPGRP 1120 Query: 1039 SPPARS--PNLPSMNNMPGM-------------GINTQNPRISGPNPVVPMPTLSPMGMT 1083 PP S P P + MPG+ G+ +P I GP P + P+ SP G+ Sbjct: 1121 GPPGSSGPPGCPGDHGMPGLRGQPGEMGDPGPRGLQG-DPGIPGP-PGIKGPSGSP-GLN 1177 Query: 1084 QPLSHSNQMPSPNAVG-PNIPPHGVPMG-PGLMSHNPIMGHGSQEPPMVPQGRMGFPQGF 1141 Q + A G ++ P G P+G PGL G PP P+G+ G P G Sbjct: 1178 GLHGLKGQKGTKGASGLHDVGPPG-PVGIPGLKGERGDPGSPGISPPG-PRGKKG-PPGP 1234 Query: 1142 PPVQSPPQQVPFPHNGPSGGQGSFPGGMGFPGEGPLGRPSNLPQSSADAALCKPGGPGGP 1201 P PP GP+G G P + PG P + D PG PG P Sbjct: 1235 PGSSGPP--------GPAGATGRAPKDIPDPGP-----PGDQGPPGPDGPRGAPGPPGLP 1281 Query: 1202 DSFTVLGNSMPSVFTDPDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRK 1261 S +L PG G+P PG Sbjct: 1282 GSVDLLRGE---------------PGDCGLPG-----------------------PPGPP 1303 Query: 1262 QPQGPGPGFSHMQGMMGEQAPRMGLALPGMGGP----GPVGTPDIPLGTAPSMPGHNPMR 1317 P GP PG+ G G+ + + PG GP GP G +P P G + Sbjct: 1304 GPPGP-PGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLP--GPPGRKGPTGLP 1360 Query: 1318 PPAFLQQGMMGPHHRMMS-PAQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGLYTHPGPVG 1376 P +G GP + P +PG P M P A+G+ PG RGP+G PG G Sbjct: 1361 GP----RGEPGPPADVDDCPRIPGLPGAPG-MRGPEGAMGL-PGM-RGPSG----PGCKG 1409 Query: 1377 SPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 PG+ +G+ G +P P G D G G+ GPG PG Sbjct: 1410 EPGLD-GRRGVDG------VPGSPGPPGRKGDTGEDGYPGGPGPPG 1448 Score = 75.9 bits (185), Expect = 3e-13 Identities = 127/461 (27%), Positives = 162/461 (35%), Gaps = 130/461 (28%) Query: 1068 PNPVVPMPTLSPMGMTQPLSHSNQMPSPNAVGP--------NIPPHGVPMGPGLMSHNPI 1119 P P P + P+G P+ S + GP + P GVP PGL + I Sbjct: 67 PGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPGL---DGI 123 Query: 1120 MGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPSGGQGSFPGGMGFPGE-GPLG 1178 GH P P+G+ G HNG G G FPGG G G GPLG Sbjct: 124 PGHPG---PPGPRGKPGMSG---------------HNGSRGDPG-FPGGRGALGPGGPLG 164 Query: 1179 RPSNLPQSSADAALC-----------KPGGPGGPDSFTVLGNSMPSVFT-DPDL----QE 1222 P + + PG PG P S+ G + P+ + +P L + Sbjct: 165 HPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQ 224 Query: 1223 VIRPGATGIPEF-------DLSRIIPSEKPSQTLQYFP------RGE------------- 1256 RPG G P D + P TL P +GE Sbjct: 225 PGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLP 284 Query: 1257 -VPGRKQPQGPG----------------------PGFSHMQGMMG--EQAPRMGLALP-- 1289 PGRK G G PGF ++G +G GL P Sbjct: 285 GPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKG 344 Query: 1290 ---GMGGPGPVG---TPDIPLGTAPSMPGH----------NPMRPPAFLQQ------GMM 1327 G PGP G TP +PL P PG P PP L + GM+ Sbjct: 345 DPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMI 404 Query: 1328 GPHHRMMSPAQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGLYTHPGPVGSPG--MMMSMQ 1385 GP P +PG+ + P +A G PGK P GL PG G PG ++ Sbjct: 405 GPPGPQGFPGLPGLPGEAGIPGRPDSAPGK-PGKPGSP-GLPGAPGLQGLPGSSVIYCSV 462 Query: 1386 GMMGPQ--QNIMIPPQMR-PRGMAADVGMGGFSQGP-GNPG 1422 G GPQ + + PP R P+G + G+ GP G PG Sbjct: 463 GNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPG 503 Score = 72.0 bits (175), Expect = 4e-12 Identities = 238/1001 (23%), Positives = 322/1001 (32%), Gaps = 196/1001 (19%) Query: 495 CSLQDMMVHQHGPRGVVRGPP-PPYQMTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHP 553 C +D V P RGPP PP P G S M P G A Sbjct: 47 CGGRDCSVCHCVPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDK 106 Query: 554 NMPGSQMRLPGFAGMINSEMEGPNVPNPASRPGLSGVSWPDDVPKIPDGRNFPPGQGIFS 613 G +PGF G+ + P P P +PG+SG + P FP G+G Sbjct: 107 GDKGPT-GVPGFPGL-DGIPGHPGPPGPRGKPGMSGHNGSRGDP------GFPGGRGAL- 157 Query: 614 GPGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPGN 673 GPG P G E ++ + LG G+ + P + +PGS P Sbjct: 158 GPG------GPLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPG---LPGSWGAGGPAG 208 Query: 674 NPIFPRIPVEGPLSPSRGDFPKGIPPQMGPGRELEFGMVPSGMKGDVNLNVNMGSNSQMI 733 +P P G + P P Q PGR G G+KG + +G Sbjct: 209 PTGYPGEP--GLVGP---------PGQ--PGRPGLKGNPGVGVKGQMGDPGEVGQQGSPG 255 Query: 734 PQKMREAGAGPEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPMSQGPGS 793 P + E P+ L G +P MV LP + E G+G + + PG Sbjct: 256 PTLLVEP---PDFCLYKGEKGIKGIPG---MVGLPGPPGRKGESGIGAKGEKGIPGFPGP 309 Query: 794 NSGLRNLREPIGPDQRTNSRLSHMPPL-----PLNPSSN-----PTSLNTAPPVQRGLGR 843 + P P + L P L P N P + PP+ L Sbjct: 310 RGDPGSYGSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLP--LKG 367 Query: 844 KPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGMLAGPAAAA 903 P D G + + P P + LG P AGM+ P Sbjct: 368 PPGDPGFPGRYGETGDVGPPGPPGL-------LGRPG---------EACAGMIGPPGPQG 411 Query: 904 SIKSPPVLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMASPAMLG 963 P + G A P P +PG P P PG P P + +G Sbjct: 412 FPGLPGLPGEAGI-------PGRPDSAPGKPGKPGSP-GLPGAPGLQGLPGSSVIYCSVG 463 Query: 964 NVE----SGGPPPPTASQPASVNIPGSLPSSTPYTM-PPEPTLSQNPLSIMMSRMSKFAM 1018 N G PP P L + P M PP P L + Sbjct: 464 NPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPP----GLPGRQGSKGDLGL 519 Query: 1019 PSSTPLYHDAIKTVASSDDDSPPARS--PNLPSMNNMPGMGINTQNPRISGPNPVVPMPT 1076 P + + D PP P LP + G P Sbjct: 520 PG----------WLGTKGDPGPPGAEGPPGLPGKHGASG--------------PPGNKGA 555 Query: 1077 LSPMGMTQPLSHSNQMPSPNAVGPNIPPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMG 1136 M +++ H + GP+ PP G P PG + GH ++ P G Sbjct: 556 KGDMVVSRVKGHKGER------GPDGPP-GFPGQPGSHGRD---GHAGEKGDPGPPG--- 602 Query: 1137 FPQGFPPVQSPPQQVPFPHNGPSGGQGSFPGGMGFPGE-GPLGRPSNLPQSSADAALCKP 1195 H + G FPG +G PG+ GP+G P L P Sbjct: 603 -----------------DHEDATPGGKGFPGPLGPPGKAGPVG-PPGLGFPGPPGERGHP 644 Query: 1196 GGPG-----GPD------------SFTVLGNSMPSVFTDPDLQEVI--RPGATGIPEFDL 1236 G PG GPD + T G P F P + GA G+ D Sbjct: 645 GVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGSDG 704 Query: 1237 SRIIPSEKPSQTLQYFP--RGEV--PG-----RKQPQGP-----GPGFSHMQGMMGEQA- 1281 + P + + P RG++ PG P GP PG + +G+ G+ A Sbjct: 705 HKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQKGIPGDPAF 764 Query: 1282 ----PRMGLALPGMGG-PGPVGTPDIPLGTAPS-MPGHNPMRPPAFLQ-----QGMMGPH 1330 P L G+ G GP G P P P+ +PG ++ P + G+ GP Sbjct: 765 GHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPP 824 Query: 1331 HRMMSPAQSTMPGQPTLMSNPAAAVGMIPGKDR-------GPAGLYTHPGPVGSPGM--M 1381 +PGQP L P + G GK + GPAG+ PG G PG Sbjct: 825 GHSCERGAPGIPGQPGLPGYPGSP-GAPGGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGP 883 Query: 1382 MSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 + G+ GP + +P P+G G GF G PG Sbjct: 884 PGLPGIPGPFGDDGLPGPPGPKGPRGLPGFPGFPGERGKPG 924 Score = 63.9 bits (154), Expect = 1e-09 Identities = 210/880 (23%), Positives = 269/880 (30%), Gaps = 204/880 (23%) Query: 387 GPQQNPGVL--DGPQKKPEGPIQAMMAQSQSLGKGPGPRTDVGAP-FGPQGHRDVPFSPD 443 GPQ PG+ DG + +P P A + PG R D+G P FG + P Sbjct: 692 GPQGAPGLSGSDGHKGRPGTPGTA------EIPGPPGFRGDMGDPGFGGEKGSSPVGPPG 745 Query: 444 EMVPPSMNSQSGTIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVH 503 P +N Q G G H+ P KR ++ Sbjct: 746 PPGSPGVNGQKGIPGDPAFGHLGPPG-------------KRGLSGVPGIKGPRGDPGCPG 792 Query: 504 QHGPRGV-----VRGP--------------PPPYQMT------PSEGWAPG--GTEPFSD 536 GP G+ ++GP PP + P + PG G+ Sbjct: 793 AEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPG 852 Query: 537 GINMPHSLPPRGMAPHPNMPGSQMRLPGFAGMINSEMEGPNVPNPASRPGLSGVSWPDDV 596 G P + P G A +PG LPG G + P +P P GL G P Sbjct: 853 GKGQPGDVGPPGPAGMKGLPG----LPGRPGA-HGPPGLPGIPGPFGDDGLPGPPGPKGP 907 Query: 597 PKIPDGRNFPPGQGIFSGPG----RGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGI 652 +P FP +G G +GE P +G+S GLP + G Sbjct: 908 RGLPGFPGFPGERGKPGAEGCPGAKGE--PGEKGMS-------------GLPGDRGLRGA 952 Query: 653 RPSMEMNRMIPGSQRHM---EPGNNPIFPRIPVEGPLSPSRGDFPKGIPPQMG----PGR 705 + ++ PG + M P P P + RGD KG P G PGR Sbjct: 953 KGAIGP----PGDEGEMAIISQKGTPGEPGPPGDDGFPGERGD--KGTPGMQGRRGEPGR 1006 Query: 706 ELEFGM--------------VPSGMKGDVNLNVNMGSNSQMIPQKMREAGA-GPEEMLKL 750 G P G G L +G +P E G+ GP + Sbjct: 1007 YGPPGFHRGEPGEKGQPGPPGPPGPPGSTGLRGFIGFPG--LPGDQGEPGSPGPPGFSGI 1064 Query: 751 ----RPGGSDMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPMSQGPGSNSGLRNLREPIGP 806 P G+ PA P P GE P P G GL ++ P G Sbjct: 1065 DGARGPKGNKGDPASHFGPPGPKGEPGS--------PGCPGHFGASGEQGLPGIQGPRGS 1116 Query: 807 DQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLDISVAGSQVHSPGINPLKSP 866 R S PP P GL +P ++ PG L+ Sbjct: 1117 PGRPGPPGSSGPPGCPGDHGMP-----------GLRGQP-------GEMGDPGPRGLQG- 1157 Query: 867 TMHQVQSPMLGSPSGNLKSPQTPSQLAGM--LAGPAAAASIKSPPVLGSAAASPVHLKSP 924 P + P G +K P L G+ L G G+ AS +H P Sbjct: 1158 ------DPGIPGPPG-IKGPSGSPGLNGLHGLKGQK-----------GTKGASGLHDVGP 1199 Query: 925 SLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMASPAMLGNVESGGPPPP---TASQPASV 981 P PG P SPGI P P G S GPP P T P + Sbjct: 1200 PGPVGIPGLKGERGDP-GSPGISP----PGPRGKKGPPGPPGSSGPPGPAGATGRAPKDI 1254 Query: 982 NIPGSLPSSTPYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPP 1041 PG P P P + P +P S L PP Sbjct: 1255 PDPGP-PGDQGPPGPDGPRGAPGPP----------GLPGSVDLLRGEPGDCGLPGPPGPP 1303 Query: 1042 ARSPNLPSMNNMPGM-GINTQNPRISGPNPVVPMPTLSP---MGMTQPLSHSNQMPSPNA 1097 P P PG G + Q + P P P P G+ P P Sbjct: 1304 G-PPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGP 1362 Query: 1098 VGPNIPP---------HGVPMGPGLMSHNPIMGHGSQEPPMVP--------QGRMGFPQG 1140 G PP G+P PG+ MG P P GR G G Sbjct: 1363 RGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGLDGRRGV-DG 1421 Query: 1141 FPPVQSPPQQVPFPHNGPSGGQGSFPGGMGFPGEGPLGRP 1180 P PP + G +G G +PGG G P GP+G P Sbjct: 1422 VPGSPGPPGR-----KGDTGEDG-YPGGPGPP--GPIGDP 1453 Score = 55.5 bits (132), Expect = 4e-07 Identities = 93/331 (28%), Positives = 119/331 (35%), Gaps = 74/331 (22%) Query: 1123 GSQEPPMVP--QGRMGFPQGFP-PVQSPPQQVPFPHNGPSGGQGS-----------FPGG 1168 GS+ PP P QG +G P G P P+ ++ GP G G FPG Sbjct: 62 GSRGPPGPPGPQGPIG-PLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPGL 120 Query: 1169 MGFPGE----GPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVI 1224 G PG GP G+P S + + PG PGG Sbjct: 121 DGIPGHPGPPGPRGKPG---MSGHNGSRGDPGFPGGR----------------------- 154 Query: 1225 RPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPGPGFSHMQGMMGEQAPRM 1284 GA G P L P EK + F G V G + +G PG + G G P Sbjct: 155 --GALG-PGGPLGH--PGEKGEKGNSVFILGAVKGIQGDRGD-PGLPGLPGSWGAGGPAG 208 Query: 1285 GLALPGMGG-PGPVGTPDIP-LGTAPSMPGHNPMRPPAFL-QQGMMGPHHRMMSPAQSTM 1341 PG G GP G P P L P + M P + QQG GP + P Sbjct: 209 PTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLY 268 Query: 1342 PGQPTLMSNPAAAVGMI--PGKD-------RGPAGLYTHPGPVGSPGMMMSMQGMMGPQQ 1392 G+ + P VG+ PG+ +G G+ PGP G PG S G G + Sbjct: 269 KGEKGIKGIPGM-VGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGS-PGFPGLKG 326 Query: 1393 NIMIPPQMRPRGMAADVGMGGFSQGPGNPGN 1423 + G+ D G+ G G+PGN Sbjct: 327 EL---------GLVGDPGLFGLIGPKGDPGN 348 Score = 39.3 bits (90), Expect = 0.027 Identities = 66/258 (25%), Positives = 79/258 (30%), Gaps = 57/258 (22%) Query: 228 RNDPKPLPQQPPAPANQDQNSSQNTRLQPTPPIPAPAPKPAAPPRPLDRESPGVENKLIP 287 R DP PP P R + PP P P + PP P + G K IP Sbjct: 1212 RGDPGSPGISPPGP-----------RGKKGPPGP---PGSSGPPGPAG--ATGRAPKDIP 1255 Query: 288 SVGSPASSTPLPPDG----TGPNSTPNNRAVTPVSQGSNS--SSADPKAPPPPPVSSGEP 341 G P P PDG GP P + + G P PP PP G P Sbjct: 1256 DPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKGFP 1315 Query: 342 PTLGEN----PDGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPGVLDG 397 G++ P G Q H FP G ++ P L G Sbjct: 1316 GCDGKDGQKGPVGFPGPQGPHG--------------FPGPPGEKGLPGPPGRKGPTGLPG 1361 Query: 398 PQKKPEGPIQA-MMAQSQSLGKGPGPRTDVGA--------PFGP--------QGHRDVPF 440 P+ +P P + L PG R GA P GP G R V Sbjct: 1362 PRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGLDGRRGVDG 1421 Query: 441 SPDEMVPPSMNSQSGTIG 458 P PP +G G Sbjct: 1422 VPGSPGPPGRKGDTGEDG 1439 Score = 34.7 bits (78), Expect = 0.67 Identities = 38/136 (27%), Positives = 50/136 (36%), Gaps = 34/136 (25%) Query: 6 PKVRSSPSGNTQSSPKSKQ--EVMVRPPTVMSPSGNPQLDSKFSNQGKQG-----GSASQ 58 P +R P P+ Q + PP + PSG+P L+ +G++G G Sbjct: 1138 PGLRGQPGEMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDV 1197 Query: 59 SQPSPC----------DSKSGGHTP------KALPGPGGSMGLKNGAGNGAKGKGKRERS 102 P P D S G +P K PGP GS G A GA G+ + Sbjct: 1198 GPPGPVGIPGLKGERGDPGSPGISPPGPRGKKGPPGPPGSSGPPGPA--GATGRAPK--- 1252 Query: 103 ISADSFDQRDPGTPND 118 D DPG P D Sbjct: 1253 ------DIPDPGPPGD 1262 Score = 32.3 bits (72), Expect = 3.3 Identities = 33/136 (24%), Positives = 45/136 (33%), Gaps = 32/136 (23%) Query: 12 PSGNTQSSPKSKQEVMVRPPTVMSPSGNPQLDSKFSNQGK---QGGSASQSQPSPCDSKS 68 P G K + + P M P G P L + ++G G ++ P P Sbjct: 477 PGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPGP----P 532 Query: 69 GGHTPKALPGPGGSMGLKNGAGNGAKG----------KGKR-------------ERSISA 105 G P LPG G+ G GAKG KG+R Sbjct: 533 GAEGPPGLPGKHGASG--PPGNKGAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHGRDG 590 Query: 106 DSFDQRDPGTPNDDSD 121 + ++ DPG P D D Sbjct: 591 HAGEKGDPGPPGDHED 606 Score = 31.6 bits (70), Expect = 5.7 Identities = 23/90 (25%), Positives = 30/90 (33%), Gaps = 7/90 (7%) Query: 30 PPTVMSPSGNPQLDSKFSNQGKQGGSASQSQPSPCDSKSGGHTPKALPGPGGSMGLKNGA 89 PP P G P +GK G C G K + G G GL+ Sbjct: 901 PPGPKGPRGLPGFPGFPGERGKPGAEG-------CPGAKGEPGEKGMSGLPGDRGLRGAK 953 Query: 90 GNGAKGKGKRERSISADSFDQRDPGTPNDD 119 G + E +I + +PG P DD Sbjct: 954 GAIGPPGDEGEMAIISQKGTPGEPGPPGDD 983 >gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] Length = 1860 Score = 112 bits (281), Expect = 2e-24 Identities = 351/1469 (23%), Positives = 471/1469 (32%), Gaps = 229/1469 (15%) Query: 51 KQGGSAS--QSQPSPCDSKSGGHTPKALPGPGGSMGLKN------GAGNGAKGKGKRERS 102 KQ G A QS P S+ G P +GL+N G+ G+G R Sbjct: 234 KQCGQADTYQSPLGPLFSQDSGR-PFTFQSDLALLGLENLTTATPALGSLPAGRGPRGTV 292 Query: 103 ISADSFDQRDPGTPNDDSDIKECNSADHIKSQDSQHTP---HSMTPSNATAPRSSTPSHG 159 P TP N H+ TP ++ SNA P G Sbjct: 293 A---------PATPTKPQRTSPTNPHQHMAVGGPAQTPLLPAKLSASNALDPMLPASVGG 343 Query: 160 QTTATEPTPAQKTPAKVVYVFSTEMANKAAEAVLKGQVETIVSFHIQNISNNKTERSTAP 219 T P AQ + + K + S I I + + TAP Sbjct: 344 STRTPRPAAAQPSQKITATKIPKSLPTKPSAP----------STSIVPIKSPHPTQKTAP 393 Query: 220 LNTQISALRNDPKPLPQQPPAPANQDQNSSQNTRLQPTPPIPAPAPKPAAPPRPLDRESP 279 + SAL + P P PA + + + + P P P P PP + P Sbjct: 394 SSFTKSALPTQKQVPPTSRPVPARVSRPAEKPIQRNPGMPRPPPPSTRPLPPTTSSSKKP 453 Query: 280 -----GVENKLIPSVGSPAS---STPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAP 331 E K+ PAS ST PP T +S+P A TP GS S+ P Sbjct: 454 IPTLARTEAKITSHASKPASARTSTHKPPPFTALSSSP---APTP---GSTRSTRPPATM 507 Query: 332 PPPPVSSGEP------PTLGENPDGLSQEQLEHRERSLQTLRDIQRMLFP--DEKEFTGA 383 PP + P PT G P G S++ + + R P K Sbjct: 508 VPPTSGTSTPRTAPAVPTPGSAPTG-SKKPIGSEASKKAGPKSSPRKPVPLRPGKAARDV 566 Query: 384 QSGGPQQNPGVLDGPQKKPEGPIQAMMAQSQSLGKGPGPRTDVGAPFGPQGHRDVPFSPD 443 P PQ + ++A +Q L P P + + F G PF P Sbjct: 567 PLSDLTTRPSPRQ-PQPSQQTTPALVLAPAQFLSSSPRPTSSGYSIFHLAG--STPF-PL 622 Query: 444 EMVPPSMNSQSGTIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVH 503 M PP G GP L + A Sbjct: 623 LMGPPGPKGDCGLPGPPGLPGLPGIPGA-------------------------------- 650 Query: 504 QHGPRGV--------VRGPPPPYQMTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNM 555 GPRG + GPP G +PG DG LP G++ +P Sbjct: 651 -RGPRGPPGPYGNPGLPGPPGAKGQKGDPGLSPGKAH---DGAKGDMGLP--GLSGNPGP 704 Query: 556 PGSQMR--LPGFAGMINSEME-GPN-VPNPASRPGLSGVSWPDDVPKIPDGRNFPPGQGI 611 PG + PG AG + + GP P PG G+ P P R + G+ Sbjct: 705 PGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGL 764 Query: 612 FSGPGR-GER-FPNPQGLSEEMFQQQLAEKQLGLP--PGMAMEGIRPSMEMNRMIPGSQR 667 F PG GER P G +M G+P PG+ E P ++ N PG Sbjct: 765 FGLPGSDGERGLPGVPGKRGKM----------GMPGFPGVFGERGPPGLDGN---PGELG 811 Query: 668 HMEPGNNPIFPRIPVEGPLSPSRGDFPKGIPPQMG----PGRELEFGM--VPSGMKGDVN 721 PG + I G L P PKG+ MG PG + + G VP G+ GD Sbjct: 812 L--PGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVP-GVSGDPG 868 Query: 722 LNVNMGSNSQMIPQKMREAGAGPEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQQEYG--- 778 + GS Q +P G P + K+ GS P P P + G Sbjct: 869 FQGDKGS--QGLPGFPGARGK-PGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEG 925 Query: 779 MGPRPFLPMSQGPGSNSGLRNLREPIGPDQRTNSRLSHMPP---LPLNPSSNPTSLNTAP 835 M +P GP G P+GP L P P P + Sbjct: 926 MKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPG--LEGQPGRKGFPGRPGLDGVKGEPGD 983 Query: 836 PVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGM 895 P + G + + G V PGI K + P + P G++ P P + Sbjct: 984 PGRPGPVGEQGFMGFIGL-VGEPGIVGEKGDR-GMMGPPGVPGPKGSMGHPGMPGGMGTP 1041 Query: 896 -LAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPL 954 GP + PP + A + P PA G PP P P Sbjct: 1042 GEPGPQGPPGSRGPPGMRGAKGRRGP-RGPDGPAGEQGSRGLKGPP--GPQGRPGRPGQQ 1098 Query: 955 TMASPAMLGNVESGGPP--PPTASQPASVNIPGSLPSSTPYTMPPEPTLSQNPLSIMMSR 1012 +A G++ S G P P + P + +PG P P Q P+ Sbjct: 1099 GVAGER--GHLGSRGFPGIPGPSGPPGTKGLPGE----------PGPQGPQGPIG-PPGE 1145 Query: 1013 MSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMGINTQNPRISGPN-PV 1071 M P + + A D P +P + G P + G + P+ Sbjct: 1146 MGPKGPPGAVG--EPGLPGEAGMKGDLGPLGTPGEQGLIGQRG------EPGLEGDSGPM 1197 Query: 1072 VPMPTLSPMGMTQPLSHSNQMPSPNAVGPNIPPHGVPMGPGLMSHNPIMGHGSQEPPMVP 1131 P G P + +G + PP G P G+ G ++ Sbjct: 1198 GPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPP-GPPGVTGVRGPEGKSGKQGEKGRTGA 1256 Query: 1132 QGRMGFPQGFPPVQSPPQQVPFPHNGPSGGQGSF-----PGGMGFPGE------------ 1174 +G G+ + P P GP G +GS PG MG GE Sbjct: 1257 KGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGI 1316 Query: 1175 -GPLGRPSNLPQSSADAALCKPGGPGGP--DSFTVLGNSMPSVFTDPDL--QEVI----- 1224 GPLG P + K GP GP D V DP QE + Sbjct: 1317 VGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRG 1376 Query: 1225 RPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPGPGFSHMQGMMGEQAPRM 1284 +PG G P R P K S+ E P KQ + PG +QG+ G PR Sbjct: 1377 KPGQQGQPGHPGPRGWPGPKGSKG------AEGPKGKQGKAGAPGRRGVQGLQGLPGPRG 1430 Query: 1285 GLALPGMGG-PGPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMSPAQSTMPG 1343 + G+ G GP G P G A P G MGP + +P + +PG Sbjct: 1431 VVGRQGLEGIAGPDGLPGRD-GQAGQQGEQGDDGDP-----GPMGPAGKRGNPGVAGLPG 1484 Query: 1344 Q--PTLMSNPAAAVGMI--PGKDRGPAGLYTHPGPVGSPGMMMSMQGMMGPQQNIMIPPQ 1399 P + G + PGK RG G PG G PG +G G + P Sbjct: 1485 AQGPPGFKGESGLPGQLGPPGK-RGTEGRTGLPGNQGEPGS----KGQPGDSGEMGFPGM 1539 Query: 1400 ---MRPRGMAADVGMGGFSQGPGNPGNMM 1425 P+G D+G G QGP P +M Sbjct: 1540 AGLFGPKGPPGDIGFKGI-QGPRGPPGLM 1567 Score = 32.7 bits (73), Expect = 2.6 Identities = 27/96 (28%), Positives = 34/96 (35%), Gaps = 6/96 (6%) Query: 33 VMSPSGNPQLDSKFSNQGKQGGSASQSQPSPCDSKSGGHTPKALPGPGGSMGLKNGAG-- 90 + P G P D + QG+QG P K G LPG G G K +G Sbjct: 1440 IAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPA-GKRGNPGVAGLPGAQGPPGFKGESGLP 1498 Query: 91 --NGAKGKGKRERSISADSFDQRDPGTPNDDSDIKE 124 G GK E +Q +PG+ D E Sbjct: 1499 GQLGPPGKRGTEGRTGLPG-NQGEPGSKGQPGDSGE 1533 >gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo sapiens] Length = 1818 Score = 112 bits (280), Expect = 3e-24 Identities = 264/1034 (25%), Positives = 347/1034 (33%), Gaps = 166/1034 (16%) Query: 506 GPRGVVRGPPPPYQMTPSEG--WAPGGT----EPFSDGINMPHSLP----------PRGM 549 GPRGV +GPP P G A GG EP + G LP RG Sbjct: 574 GPRGV-QGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGP 632 Query: 550 APHPNMPGSQ-MR----------LPGFAGMINSEMEGPN-VPNPASRPGLSGVSWPDDVP 597 P PG MR LPG AG + GP P +PG++GV P P Sbjct: 633 QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRG--LLGPRGTPGAPGQPGMAGVDGPPG-P 689 Query: 598 KI---PDGRNFPPGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRP 654 K P G PPGQ GP + P PQG EK PG+A G+ P Sbjct: 690 KGNMGPQGEPGPPGQQGNPGP---QGLPGPQGPIGPP-----GEKGPQGKPGLA--GL-P 738 Query: 655 SMEMNRMIPGSQRHM-EPGN-NPIFPRIPV--EGPLSPSRGDFPKGIPPQMGPGRELEFG 710 + PG + E G P P+ P+ GP D +G+ G E F Sbjct: 739 GADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGF- 797 Query: 711 MVPSGMKGDVNLNVNMGSNSQMIPQKMREAGAGPEEMLKLR--PGGSDMLPAQQKMVPLP 768 G KGD+ L + G Q+ P+ + GP+ PG S + K+ Sbjct: 798 ---PGFKGDMGLKGDRGEVGQIGPRG-EDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPG 853 Query: 769 FGEHPQQEYGMGPRPFLPMSQGPGSNS-----------GLRNLREPIGPDQRTNSRLSHM 817 +P ++ GP+ PG+N G R R P GP +R Sbjct: 854 LPGYPGRQ---GPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTG 910 Query: 818 PPLPLNPSSNPTSLNTAPPVQRGLGRKPLDISVAGSQ--VHSPGINPLKSPTMHQVQSPM 875 P P S PP +RG + G + PG + L + ++ Sbjct: 911 KPGPKGTSGGDGP--PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGF 968 Query: 876 LGSPS----GNLKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSP 931 G G + PQ P+ G + G PP G K + P P Sbjct: 969 QGKTGPPGPGGVVGPQGPTGETGPI-GERGHPGPPGPP--GEQGLPGAAGKEGAKGDPGP 1025 Query: 932 GWTSSPKPPLQSPGIPPNHKAPLTMASPAMLGNVESGGPPPPTASQPASVNIPGSLPSST 991 S P G P P +P + G GPP P S GS ++ Sbjct: 1026 QGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER----GSAGTAG 1081 Query: 992 PYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMN 1051 P +P P Q P + + P D ++ + PA SP Sbjct: 1082 PIGLPGRPG-PQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1140 Query: 1052 NM---PGMGINTQNPRISGPN--PVVPMPTLSP--------------MGMTQPLSHSNQM 1092 PG + + +GP P + P +P GM Sbjct: 1141 GEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR 1200 Query: 1093 PSPNAVGPNIPPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVP 1152 P GP I G+P PG N +G P P+G G P G Q PP V Sbjct: 1201 GFPGPPGP-IGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQG-PNGADGPQGPPGSVG 1258 Query: 1153 FPHNGPSGGQGSFPGGMGFPGE----GPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLG 1208 G+ G G PGE GP G ++ A PG G P G Sbjct: 1259 SVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKG 1318 Query: 1209 NSMPSVFTDPDLQEVIRPGATGIPEFDLSRIIPSEK-----PSQTLQYFPRGEV--PGRK 1261 N P F PG G P + +K P Q P GE PG Sbjct: 1319 NPGPVGFPGD-------PGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPP 1371 Query: 1262 QPQGPGPGFSHMQGMMGEQAPRMGLALPGMGGP-GPVGTPDIPLGTAPSMPGHNPMR--P 1318 +GP PG + +G GE+ + G G GPVG P P G PG +R P Sbjct: 1372 GKRGP-PGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVG-PQGPAGK----PGPEGLRGIP 1425 Query: 1319 PAFLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAAA--------VGMI--PGK-----DR 1363 +QG+ G + P PG P L +P + +G+I PG+ DR Sbjct: 1426 GPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDR 1485 Query: 1364 GPAGLYTHPG------------PVGSPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGM 1411 G G PG P+G PG + G GP+ N P G D G+ Sbjct: 1486 GLPGTQGSPGAKGDGGIPGPAGPLGPPGPP-GLPGPQGPKGN---KGSTGPAGQKGDSGL 1541 Query: 1412 GGFSQGPGNPGNMM 1425 G PG PG ++ Sbjct: 1542 PGPPGSPGPPGEVI 1555 Score = 107 bits (268), Expect = 6e-23 Identities = 280/1140 (24%), Positives = 371/1140 (32%), Gaps = 189/1140 (16%) Query: 420 PGPRTDVG--APFGPQGHRDVPFSPDEMVP---PSMNSQSGTIGPDHLDHMTPEQIAWLK 474 PGP G P G QG P P + P P + G GP M P + Sbjct: 456 PGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDG 515 Query: 475 LQQEFYEEKRRKQEQVVVQQCSL----------------------------QDMMVHQHG 506 + + Q Q ++QQ + + G Sbjct: 516 SKGPTI-SAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQG 574 Query: 507 PRGVVRGPPPPYQMTPSEG--WAPGGT----EPFSDGINMPHSLP----------PRGMA 550 PRG V+GPP P G A GG EP + G LP RG Sbjct: 575 PRG-VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQ 633 Query: 551 PHPNMPGSQ-MR----------LPGFAGMINSEMEGP-NVPNPASRPGLSGVSWPDDVPK 598 P PG MR LPG AG + GP P +PG++GV P PK Sbjct: 634 GPPGPPGDDGMRGEDGEIGPRGLPGEAG--PRGLLGPRGTPGAPGQPGMAGVDGPPG-PK 690 Query: 599 ---IPDGRNFPPGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRPS 655 P G PPGQ GP + P PQG EK PG+A G+ P Sbjct: 691 GNMGPQGEPGPPGQQGNPGP---QGLPGPQGPIGPP-----GEKGPQGKPGLA--GL-PG 739 Query: 656 MEMNRMIPG--SQRHMEPGNNPIFPRIPV--EGPLSPSRGDFPKGIPPQMGPGRELEFGM 711 + PG Q + P P+ P+ GP D +G+ G E F Sbjct: 740 ADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGF-- 797 Query: 712 VPSGMKGDVNLNVNMGSNSQMIPQ-----KMREAGAGPEEMLKLRPGGSDMLPAQQKMVP 766 G KGD+ L + G Q+ P+ + + AGP PG S + K+ Sbjct: 798 --PGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTG----DPGPSGQAGEKGKLGV 851 Query: 767 LPFGEHPQQEYGMGPRPFLPMSQGPGSNS-----------GLRNLREPIGPDQRTNSRLS 815 +P ++ GP+ PG+N G R R P GP +R Sbjct: 852 PGLPGYPGRQ---GPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 908 Query: 816 HMPPLPLNPSSNPTSLNTAPPVQRGL--GRKPLDISVAGSQVHSPGINPLKSPTMHQVQS 873 P P S PP +RG + P+ PG + L + ++ Sbjct: 909 TGKPGPKGTSGGDGP--PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGET 966 Query: 874 PMLGSPS----GNLKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAP 929 G G + PQ P+ G + G PP G K + P Sbjct: 967 GFQGKTGPPGPGGVVGPQGPTGETGPI-GERGHPGPPGPP--GEQGLPGAAGKEGAKGDP 1023 Query: 930 SPGWTSSPKPPLQSPGIPPNHKAPLTMASPAMLGNVESGGPPPPTASQPASVNIPGSLPS 989 P S P G P P +P + G GPP P S GS + Sbjct: 1024 GPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER----GSAGT 1079 Query: 990 STPYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPS 1049 + P +P P Q P + + P D ++ + PA SP Sbjct: 1080 AGPIGLPGRPG-PQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDG 1138 Query: 1050 MN---NMPGMGINTQNPRISGP--NPVVPMPTLSP--------------MGMTQPLSHSN 1090 PG + + +GP P + P +P GM Sbjct: 1139 DKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEG 1198 Query: 1091 QMPSPNAVGPNIPPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQ 1150 P GP I G+P PG N +G P P+G G P G Q PP Sbjct: 1199 ARGFPGPPGP-IGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQG-PNGADGPQGPPGS 1256 Query: 1151 VPFPHNGPSGGQGSFPGGMGFPGE----GPLGRPSNLPQSSADAALCKPGGPGGPDSFTV 1206 V G+ G G PGE GP G ++ A PG G P Sbjct: 1257 VGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGP 1316 Query: 1207 LGNSMPSVFTDPDLQEVIRPGATGIPEFDLSRIIPSEK-----PSQTLQYFPRGEV--PG 1259 GN P F PG G P + +K P Q P GE PG Sbjct: 1317 KGNPGPVGFPGD-------PGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG 1369 Query: 1260 RKQPQGPGPGFSHMQGMMGEQAPRMGLALPG-MGGPGPVGTPDIPLGTAPSMPGHNPMR- 1317 +GP PG + +G GE+ + G G GPVG P P G PG +R Sbjct: 1370 PPGKRGP-PGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVG-PQGPAG----KPGPEGLRG 1423 Query: 1318 -PPAFLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAA--------AVGMI-PGKDRGPAG 1367 P +QG+ G + P PG P L +P + +G+I P ++G G Sbjct: 1424 IPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKG 1483 Query: 1368 LYTHPGPVGSPGM-----MMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 PG GSPG + G +GP +P P+G G G G PG Sbjct: 1484 DRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPG 1543 Score = 86.7 bits (213), Expect = 1e-16 Identities = 268/1077 (24%), Positives = 351/1077 (32%), Gaps = 186/1077 (17%) Query: 454 SGTIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQ----DMMV------- 502 SGT P+ ++ + E+ L E Y+ +R+ E + + + D++V Sbjct: 338 SGTNEPNPVEEIFTEEY----LTGEDYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEY 393 Query: 503 --HQHGPRGVVRGPPPPYQMTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPGSQM 560 +++ PP + P P T+ IN + +G P + M Sbjct: 394 DFYEYKEYEDKPTSPPNEEFGPG---VPAETDITETSINGHGAYGEKGQKGEPAVVEPGM 450 Query: 561 RLPGFAGMINSE--MEGPNVPNPASRPGLSGVSWPDDVPKIP--DGRNFPPGQGI---FS 613 + G G M P + P PG G P P +P DG PPG + F Sbjct: 451 LVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFR 510 Query: 614 GPGRGERFPNPQGLSEEMFQQQLAEKQLGL--PPG-MAMEGIRPSMEMNRMIPGSQRHM- 669 G G + P E Q L + ++ L PPG M + G RP G++ Sbjct: 511 YGGDGSKGPTISA-QEAQAQAILQQARIALRGPPGPMGLTG-RPGPVGGPGSSGAKGESG 568 Query: 670 EPGNNPIFPRIPVEGPLSPS-----RG----DFPKGIPPQMGPGRELEFGMVPSGMKGDV 720 +PG P PR V+GP P+ RG D +G+P + G + F +P G+ GD Sbjct: 569 DPG--PQGPR-GVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLP-GLPGDK 624 Query: 721 NLNVNMGSNSQMIP---QKMR----EAG-------AGPEEMLKLRPGGSDMLPAQQKMVP 766 G P MR E G AGP +L P G+ P Q M Sbjct: 625 GHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLG--PRGTPGAPGQPGMAG 682 Query: 767 LPFGEHPQQEYGMGPRPFLPMSQGPGSNSGLRNLREPIGPDQRTNSR----LSHMPPL-- 820 + P+ G P P QG GL + PIGP + L+ +P Sbjct: 683 VDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADG 742 Query: 821 -PLNPSSNPTSLN---TAPPVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPML 876 P +P S PP +G P V G+ G+ LK + + Sbjct: 743 PPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGAD----GVRGLKGSKGEKGEDGFP 798 Query: 877 GSPSG-NLKSPQTPSQLAGMLA-----GPAAAASIKSPPVLGSAAASPVHLKSPSLPAPS 930 G LK + G GP A P A L P LP Sbjct: 799 GFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPG-Y 857 Query: 931 PGWTSSPKPPLQSPGIPPNHKAPLTMASPAMLGNVESGGPPPPTASQPASVNIPGSLPSS 990 PG PK PG P + G GP P S+ A P Sbjct: 858 PG-RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKG 916 Query: 991 TP-YTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARS--PNL 1047 T PP P + P F P P PP + P Sbjct: 917 TSGGDGPPGPPGERGPQG--PQGPVGFPGPKGPP---------------GPPGKDGLPGH 959 Query: 1048 PSMNNMPGMGINTQNPRISGPNPVVPMPTLSPMGMTQPLSHSNQMPSPNAVGPNIPPHGV 1107 P G T P GP VV P G T P+ P G G+ Sbjct: 960 PGQRGETGFQGKTGPP---GPGGVV--GPQGPTGETGPIGERGHPGPPGPPG----EQGL 1010 Query: 1108 PMGPGLMSHNPIMGHGSQEPPMVPQGRMGFP--QGFPPVQSPPQQVPFPHNGPSGGQG-- 1163 P G G P G GFP +G P Q P G GG+G Sbjct: 1011 PGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP--------GLKGGEGPQ 1062 Query: 1164 SFPGGMGFPGE-------GPLGRPSNL-PQSSADAALCK-------PGGPGGPDSFT--- 1205 PG +G PGE GP+G P PQ A K P GP G D Sbjct: 1063 GPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPV 1122 Query: 1206 -VLGNSMP--SVFTDPDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQ 1262 + G + P S D D E+ PG G + D P P +G V Sbjct: 1123 GLPGPAGPAGSPGEDGDKGEIGEPGQKG-SKGDKGENGPPGPPGL------QGPVGAPGI 1175 Query: 1263 PQGPG-PGFSHMQGMMGEQAPRMGLALPGMGGPGPVGTPDIPLGTAPSMPGHN----PMR 1317 G G PG QGM G++ P G PGP+G +P P G N PM Sbjct: 1176 AGGDGEPGPRGQQGMFGQKGDEGARGFP--GPPGPIGLQGLP--GPPGEKGENGDVGPMG 1231 Query: 1318 PPAFLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAAAVGMIPG-KDRGPAGLYTHPGPVG 1376 PP G GP P + P P +VG + G ++G G +PGP G Sbjct: 1232 PPG--PPGPRGP----QGPNGADGP------QGPPGSVGSVGGVGEKGEPGEAGNPGPPG 1279 Query: 1377 SPGM-----------MMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 G+ G GP P P+G VG G PG PG Sbjct: 1280 EAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPG 1336 Score = 60.1 bits (144), Expect = 1e-08 Identities = 183/717 (25%), Positives = 234/717 (32%), Gaps = 121/717 (16%) Query: 261 PAPAPKPAAPPRPLDRESPGVENKLIPSVGSPASSTPLPPDGTGPNSTPNNRAVTPVSQG 320 P P K P P R G + K G P + P G + P P Sbjct: 948 PGPPGKDGLPGHPGQRGETGFQGK----TGPPGPGGVVGPQGPTGETGPIGERGHP---- 999 Query: 321 SNSSSADPKAPPPPPVSSGEPPTLGEN-------PDGLSQEQLEHRERSLQTLRDIQRML 373 PP PP G P G+ P G+S + R Sbjct: 1000 ---------GPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRG----------- 1039 Query: 374 FPDEKEFTGAQSGGPQQNPGVLDGPQKKPEGPIQAMMAQSQSLGKGPGPRTDVGAPFGPQ 433 FP E+ GAQ G P G +GPQ P GP+ + + + GP P GP Sbjct: 1040 FPGERGLPGAQ-GAPGLKGG--EGPQGPP-GPVGSPGERGSAGTAGPIGLPGRPGPQGPP 1095 Query: 434 GHRDVPFSPDEMVPPSMNSQSGTIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQ 493 G +P E P + G GP L P A E+ + + Q Sbjct: 1096 GPAGEKGAPGEKGPQGPAGRDGVQGPVGLP--GPAGPAGSP-----GEDGDKGEIGEPGQ 1148 Query: 494 QCSLQDMMVHQHGPRGVVRGPPPPYQMTPSEGWAPGGTEPFSDG-INMPHSLPPRGMAPH 552 + S D ++GP GPP + G A G EP G M G Sbjct: 1149 KGSKGDK--GENGP----PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGF 1202 Query: 553 PNMPGSQMRLPGFAGMINSEMEGPNVPNPASRPGLSGVSWPDDVPKIPDGRNFPPGQGIF 612 P PG + L G G + E +V P PG G P P DG PPG + Sbjct: 1203 PGPPG-PIGLQGLPGPPGEKGENGDV-GPMGPPGPPGPRGPQG-PNGADGPQGPPG-SVG 1258 Query: 613 SGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPG 672 S G GE+ + E PPG A G P +R + Sbjct: 1259 SVGGVGEK-------------GEPGEAGNPGPPGEAGVG----------GPKGERGEKGE 1295 Query: 673 NNPIFPRIPVEGPLSPSRGDFPKGIPPQMG----PGRELEFGMV-PSGMKGDVNLNVNMG 727 P P G P D PKG P +G PG E G G+ GD + + G Sbjct: 1296 AGPPGAAGP-PGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPG 1354 Query: 728 SNSQMIPQKMREAGAGPEEMLKLRPG--GSDMLPAQQKMVPLPFGEHPQQEYG-MGPRPF 784 P EAG + PG G++ ++ E P + G +GP Sbjct: 1355 QPGP--PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGP--- 1409 Query: 785 LPMSQGPGSN---SGLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGL 841 QGP GLR + P+G + PP P+ P P GL Sbjct: 1410 ----QGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLP-----------GL 1454 Query: 842 GRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGMLAGPAA 901 P G + H PG+ L P Q + G P G SP G + GPA Sbjct: 1455 KGDP---GSKGEKGH-PGLIGLIGPPGEQGEKGDRGLP-GTQGSPGAKGD--GGIPGPAG 1507 Query: 902 AASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMAS 958 PP L P K + PA G + P PP SPG P PL + S Sbjct: 1508 PLGPPGPPGL-PGPQGPKGNKGSTGPAGQKGDSGLPGPP-GSPGPPGEVIQPLPILS 1562 Score = 35.0 bits (79), Expect = 0.52 Identities = 97/409 (23%), Positives = 128/409 (31%), Gaps = 87/409 (21%) Query: 231 PKPLPQQ--PPAPANQDQNSSQNTRLQPTPPIPAPAPKPAAPPRPLDRESPGVENKL--I 286 P P+ Q P P + +N P PP P P P + PG + + Sbjct: 1206 PGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGP--QGPPGSVGSVGGV 1263 Query: 287 PSVGSPASS-TPLPPDGTGPNSTPNNR----------AVTPVSQGSNSSSADPKAPPPPP 335 G P + P PP G R A P PK P P Sbjct: 1264 GEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1323 Query: 336 VSSGEPPTLGE----NPDGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQS-GGPQQ 390 G+P GE DG+ ++ E + P + G GP Sbjct: 1324 GFPGDPGPPGEPGPAGQDGVGGDKGEDGD--------------PGQPGPPGPSGEAGPPG 1369 Query: 391 NPGVLDGPQKK-PEGPIQAMMAQSQSLGKGP-------GPRTDVGAPFGPQGHRDVPFSP 442 PG P EG A+ ++ +GP GP+ G P GP+G R +P Sbjct: 1370 PPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKP-GPEGLRGIPGPV 1428 Query: 443 DEMVPPSMNSQSGTIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMV 502 E P Q G GP M P + LK EK ++ Q Sbjct: 1429 GEQGLPGAAGQDGPPGP-----MGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG--- 1480 Query: 503 HQHGPRGVVRGPPPPYQMTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPGSQMRL 562 + G RG+ P +PG DG +P P G P +PG Q Sbjct: 1481 -EKGDRGL-----------PGTQGSPGAK---GDG-GIPGPAGPLGPPGPPGLPGPQ--- 1521 Query: 563 PGFAGMINSEMEGPNVPNPASRPGLSGVSWPDDVPKIPDGRNFPPGQGI 611 G G S PA + G SG+ P P PPG+ I Sbjct: 1522 -GPKGNKGS-------TGPAGQKGDSGLPGPPGSPG-------PPGEVI 1555 >gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo sapiens] Length = 1767 Score = 112 bits (280), Expect = 3e-24 Identities = 264/1034 (25%), Positives = 347/1034 (33%), Gaps = 166/1034 (16%) Query: 506 GPRGVVRGPPPPYQMTPSEG--WAPGGT----EPFSDGINMPHSLP----------PRGM 549 GPRGV +GPP P G A GG EP + G LP RG Sbjct: 523 GPRGV-QGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGP 581 Query: 550 APHPNMPGSQ-MR----------LPGFAGMINSEMEGPN-VPNPASRPGLSGVSWPDDVP 597 P PG MR LPG AG + GP P +PG++GV P P Sbjct: 582 QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRG--LLGPRGTPGAPGQPGMAGVDGPPG-P 638 Query: 598 KI---PDGRNFPPGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRP 654 K P G PPGQ GP + P PQG EK PG+A G+ P Sbjct: 639 KGNMGPQGEPGPPGQQGNPGP---QGLPGPQGPIGPP-----GEKGPQGKPGLA--GL-P 687 Query: 655 SMEMNRMIPGSQRHM-EPGN-NPIFPRIPV--EGPLSPSRGDFPKGIPPQMGPGRELEFG 710 + PG + E G P P+ P+ GP D +G+ G E F Sbjct: 688 GADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGF- 746 Query: 711 MVPSGMKGDVNLNVNMGSNSQMIPQKMREAGAGPEEMLKLR--PGGSDMLPAQQKMVPLP 768 G KGD+ L + G Q+ P+ + GP+ PG S + K+ Sbjct: 747 ---PGFKGDMGLKGDRGEVGQIGPRG-EDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPG 802 Query: 769 FGEHPQQEYGMGPRPFLPMSQGPGSNS-----------GLRNLREPIGPDQRTNSRLSHM 817 +P ++ GP+ PG+N G R R P GP +R Sbjct: 803 LPGYPGRQ---GPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTG 859 Query: 818 PPLPLNPSSNPTSLNTAPPVQRGLGRKPLDISVAGSQ--VHSPGINPLKSPTMHQVQSPM 875 P P S PP +RG + G + PG + L + ++ Sbjct: 860 KPGPKGTSGGDGP--PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGF 917 Query: 876 LGSPS----GNLKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSP 931 G G + PQ P+ G + G PP G K + P P Sbjct: 918 QGKTGPPGPGGVVGPQGPTGETGPI-GERGHPGPPGPP--GEQGLPGAAGKEGAKGDPGP 974 Query: 932 GWTSSPKPPLQSPGIPPNHKAPLTMASPAMLGNVESGGPPPPTASQPASVNIPGSLPSST 991 S P G P P +P + G GPP P S GS ++ Sbjct: 975 QGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER----GSAGTAG 1030 Query: 992 PYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMN 1051 P +P P Q P + + P D ++ + PA SP Sbjct: 1031 PIGLPGRPG-PQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1089 Query: 1052 NM---PGMGINTQNPRISGPN--PVVPMPTLSP--------------MGMTQPLSHSNQM 1092 PG + + +GP P + P +P GM Sbjct: 1090 GEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR 1149 Query: 1093 PSPNAVGPNIPPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVP 1152 P GP I G+P PG N +G P P+G G P G Q PP V Sbjct: 1150 GFPGPPGP-IGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQG-PNGADGPQGPPGSVG 1207 Query: 1153 FPHNGPSGGQGSFPGGMGFPGE----GPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLG 1208 G+ G G PGE GP G ++ A PG G P G Sbjct: 1208 SVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKG 1267 Query: 1209 NSMPSVFTDPDLQEVIRPGATGIPEFDLSRIIPSEK-----PSQTLQYFPRGEV--PGRK 1261 N P F PG G P + +K P Q P GE PG Sbjct: 1268 NPGPVGFPGD-------PGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPP 1320 Query: 1262 QPQGPGPGFSHMQGMMGEQAPRMGLALPGMGGP-GPVGTPDIPLGTAPSMPGHNPMR--P 1318 +GP PG + +G GE+ + G G GPVG P P G PG +R P Sbjct: 1321 GKRGP-PGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVG-PQGPAGK----PGPEGLRGIP 1374 Query: 1319 PAFLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAAA--------VGMI--PGK-----DR 1363 +QG+ G + P PG P L +P + +G+I PG+ DR Sbjct: 1375 GPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDR 1434 Query: 1364 GPAGLYTHPG------------PVGSPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGM 1411 G G PG P+G PG + G GP+ N P G D G+ Sbjct: 1435 GLPGTQGSPGAKGDGGIPGPAGPLGPPGPP-GLPGPQGPKGN---KGSTGPAGQKGDSGL 1490 Query: 1412 GGFSQGPGNPGNMM 1425 G PG PG ++ Sbjct: 1491 PGPPGSPGPPGEVI 1504 Score = 107 bits (268), Expect = 6e-23 Identities = 280/1140 (24%), Positives = 371/1140 (32%), Gaps = 189/1140 (16%) Query: 420 PGPRTDVG--APFGPQGHRDVPFSPDEMVP---PSMNSQSGTIGPDHLDHMTPEQIAWLK 474 PGP G P G QG P P + P P + G GP M P + Sbjct: 405 PGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDG 464 Query: 475 LQQEFYEEKRRKQEQVVVQQCSL----------------------------QDMMVHQHG 506 + + Q Q ++QQ + + G Sbjct: 465 SKGPTI-SAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQG 523 Query: 507 PRGVVRGPPPPYQMTPSEG--WAPGGT----EPFSDGINMPHSLP----------PRGMA 550 PRG V+GPP P G A GG EP + G LP RG Sbjct: 524 PRG-VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQ 582 Query: 551 PHPNMPGSQ-MR----------LPGFAGMINSEMEGP-NVPNPASRPGLSGVSWPDDVPK 598 P PG MR LPG AG + GP P +PG++GV P PK Sbjct: 583 GPPGPPGDDGMRGEDGEIGPRGLPGEAG--PRGLLGPRGTPGAPGQPGMAGVDGPPG-PK 639 Query: 599 ---IPDGRNFPPGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRPS 655 P G PPGQ GP + P PQG EK PG+A G+ P Sbjct: 640 GNMGPQGEPGPPGQQGNPGP---QGLPGPQGPIGPP-----GEKGPQGKPGLA--GL-PG 688 Query: 656 MEMNRMIPG--SQRHMEPGNNPIFPRIPV--EGPLSPSRGDFPKGIPPQMGPGRELEFGM 711 + PG Q + P P+ P+ GP D +G+ G E F Sbjct: 689 ADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGF-- 746 Query: 712 VPSGMKGDVNLNVNMGSNSQMIPQ-----KMREAGAGPEEMLKLRPGGSDMLPAQQKMVP 766 G KGD+ L + G Q+ P+ + + AGP PG S + K+ Sbjct: 747 --PGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTG----DPGPSGQAGEKGKLGV 800 Query: 767 LPFGEHPQQEYGMGPRPFLPMSQGPGSNS-----------GLRNLREPIGPDQRTNSRLS 815 +P ++ GP+ PG+N G R R P GP +R Sbjct: 801 PGLPGYPGRQ---GPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 857 Query: 816 HMPPLPLNPSSNPTSLNTAPPVQRGL--GRKPLDISVAGSQVHSPGINPLKSPTMHQVQS 873 P P S PP +RG + P+ PG + L + ++ Sbjct: 858 TGKPGPKGTSGGDGP--PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGET 915 Query: 874 PMLGSPS----GNLKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAP 929 G G + PQ P+ G + G PP G K + P Sbjct: 916 GFQGKTGPPGPGGVVGPQGPTGETGPI-GERGHPGPPGPP--GEQGLPGAAGKEGAKGDP 972 Query: 930 SPGWTSSPKPPLQSPGIPPNHKAPLTMASPAMLGNVESGGPPPPTASQPASVNIPGSLPS 989 P S P G P P +P + G GPP P S GS + Sbjct: 973 GPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER----GSAGT 1028 Query: 990 STPYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPS 1049 + P +P P Q P + + P D ++ + PA SP Sbjct: 1029 AGPIGLPGRPG-PQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDG 1087 Query: 1050 MN---NMPGMGINTQNPRISGP--NPVVPMPTLSP--------------MGMTQPLSHSN 1090 PG + + +GP P + P +P GM Sbjct: 1088 DKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEG 1147 Query: 1091 QMPSPNAVGPNIPPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQ 1150 P GP I G+P PG N +G P P+G G P G Q PP Sbjct: 1148 ARGFPGPPGP-IGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQG-PNGADGPQGPPGS 1205 Query: 1151 VPFPHNGPSGGQGSFPGGMGFPGE----GPLGRPSNLPQSSADAALCKPGGPGGPDSFTV 1206 V G+ G G PGE GP G ++ A PG G P Sbjct: 1206 VGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGP 1265 Query: 1207 LGNSMPSVFTDPDLQEVIRPGATGIPEFDLSRIIPSEK-----PSQTLQYFPRGEV--PG 1259 GN P F PG G P + +K P Q P GE PG Sbjct: 1266 KGNPGPVGFPGD-------PGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG 1318 Query: 1260 RKQPQGPGPGFSHMQGMMGEQAPRMGLALPG-MGGPGPVGTPDIPLGTAPSMPGHNPMR- 1317 +GP PG + +G GE+ + G G GPVG P P G PG +R Sbjct: 1319 PPGKRGP-PGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVG-PQGPAG----KPGPEGLRG 1372 Query: 1318 -PPAFLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAA--------AVGMI-PGKDRGPAG 1367 P +QG+ G + P PG P L +P + +G+I P ++G G Sbjct: 1373 IPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKG 1432 Query: 1368 LYTHPGPVGSPGM-----MMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 PG GSPG + G +GP +P P+G G G G PG Sbjct: 1433 DRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPG 1492 Score = 86.7 bits (213), Expect = 1e-16 Identities = 268/1077 (24%), Positives = 351/1077 (32%), Gaps = 186/1077 (17%) Query: 454 SGTIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQ----DMMV------- 502 SGT P+ ++ + E+ L E Y+ +R+ E + + + D++V Sbjct: 287 SGTNEPNPVEEIFTEEY----LTGEDYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEY 342 Query: 503 --HQHGPRGVVRGPPPPYQMTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPGSQM 560 +++ PP + P P T+ IN + +G P + M Sbjct: 343 DFYEYKEYEDKPTSPPNEEFGPG---VPAETDITETSINGHGAYGEKGQKGEPAVVEPGM 399 Query: 561 RLPGFAGMINSE--MEGPNVPNPASRPGLSGVSWPDDVPKIP--DGRNFPPGQGI---FS 613 + G G M P + P PG G P P +P DG PPG + F Sbjct: 400 LVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFR 459 Query: 614 GPGRGERFPNPQGLSEEMFQQQLAEKQLGL--PPG-MAMEGIRPSMEMNRMIPGSQRHM- 669 G G + P E Q L + ++ L PPG M + G RP G++ Sbjct: 460 YGGDGSKGPTISA-QEAQAQAILQQARIALRGPPGPMGLTG-RPGPVGGPGSSGAKGESG 517 Query: 670 EPGNNPIFPRIPVEGPLSPS-----RG----DFPKGIPPQMGPGRELEFGMVPSGMKGDV 720 +PG P PR V+GP P+ RG D +G+P + G + F +P G+ GD Sbjct: 518 DPG--PQGPR-GVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLP-GLPGDK 573 Query: 721 NLNVNMGSNSQMIP---QKMR----EAG-------AGPEEMLKLRPGGSDMLPAQQKMVP 766 G P MR E G AGP +L P G+ P Q M Sbjct: 574 GHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLG--PRGTPGAPGQPGMAG 631 Query: 767 LPFGEHPQQEYGMGPRPFLPMSQGPGSNSGLRNLREPIGPDQRTNSR----LSHMPPL-- 820 + P+ G P P QG GL + PIGP + L+ +P Sbjct: 632 VDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADG 691 Query: 821 -PLNPSSNPTSLN---TAPPVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPML 876 P +P S PP +G P V G+ G+ LK + + Sbjct: 692 PPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGAD----GVRGLKGSKGEKGEDGFP 747 Query: 877 GSPSG-NLKSPQTPSQLAGMLA-----GPAAAASIKSPPVLGSAAASPVHLKSPSLPAPS 930 G LK + G GP A P A L P LP Sbjct: 748 GFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPG-Y 806 Query: 931 PGWTSSPKPPLQSPGIPPNHKAPLTMASPAMLGNVESGGPPPPTASQPASVNIPGSLPSS 990 PG PK PG P + G GP P S+ A P Sbjct: 807 PG-RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKG 865 Query: 991 TP-YTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARS--PNL 1047 T PP P + P F P P PP + P Sbjct: 866 TSGGDGPPGPPGERGPQG--PQGPVGFPGPKGPP---------------GPPGKDGLPGH 908 Query: 1048 PSMNNMPGMGINTQNPRISGPNPVVPMPTLSPMGMTQPLSHSNQMPSPNAVGPNIPPHGV 1107 P G T P GP VV P G T P+ P G G+ Sbjct: 909 PGQRGETGFQGKTGPP---GPGGVV--GPQGPTGETGPIGERGHPGPPGPPG----EQGL 959 Query: 1108 PMGPGLMSHNPIMGHGSQEPPMVPQGRMGFP--QGFPPVQSPPQQVPFPHNGPSGGQG-- 1163 P G G P G GFP +G P Q P G GG+G Sbjct: 960 PGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP--------GLKGGEGPQ 1011 Query: 1164 SFPGGMGFPGE-------GPLGRPSNL-PQSSADAALCK-------PGGPGGPDSFT--- 1205 PG +G PGE GP+G P PQ A K P GP G D Sbjct: 1012 GPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPV 1071 Query: 1206 -VLGNSMP--SVFTDPDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQ 1262 + G + P S D D E+ PG G + D P P +G V Sbjct: 1072 GLPGPAGPAGSPGEDGDKGEIGEPGQKG-SKGDKGENGPPGPPGL------QGPVGAPGI 1124 Query: 1263 PQGPG-PGFSHMQGMMGEQAPRMGLALPGMGGPGPVGTPDIPLGTAPSMPGHN----PMR 1317 G G PG QGM G++ P G PGP+G +P P G N PM Sbjct: 1125 AGGDGEPGPRGQQGMFGQKGDEGARGFP--GPPGPIGLQGLP--GPPGEKGENGDVGPMG 1180 Query: 1318 PPAFLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAAAVGMIPG-KDRGPAGLYTHPGPVG 1376 PP G GP P + P P +VG + G ++G G +PGP G Sbjct: 1181 PPG--PPGPRGP----QGPNGADGP------QGPPGSVGSVGGVGEKGEPGEAGNPGPPG 1228 Query: 1377 SPGM-----------MMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 G+ G GP P P+G VG G PG PG Sbjct: 1229 EAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPG 1285 Score = 60.1 bits (144), Expect = 1e-08 Identities = 183/717 (25%), Positives = 234/717 (32%), Gaps = 121/717 (16%) Query: 261 PAPAPKPAAPPRPLDRESPGVENKLIPSVGSPASSTPLPPDGTGPNSTPNNRAVTPVSQG 320 P P K P P R G + K G P + P G + P P Sbjct: 897 PGPPGKDGLPGHPGQRGETGFQGK----TGPPGPGGVVGPQGPTGETGPIGERGHP---- 948 Query: 321 SNSSSADPKAPPPPPVSSGEPPTLGEN-------PDGLSQEQLEHRERSLQTLRDIQRML 373 PP PP G P G+ P G+S + R Sbjct: 949 ---------GPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRG----------- 988 Query: 374 FPDEKEFTGAQSGGPQQNPGVLDGPQKKPEGPIQAMMAQSQSLGKGPGPRTDVGAPFGPQ 433 FP E+ GAQ G P G +GPQ P GP+ + + + GP P GP Sbjct: 989 FPGERGLPGAQ-GAPGLKGG--EGPQGPP-GPVGSPGERGSAGTAGPIGLPGRPGPQGPP 1044 Query: 434 GHRDVPFSPDEMVPPSMNSQSGTIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQ 493 G +P E P + G GP L P A E+ + + Q Sbjct: 1045 GPAGEKGAPGEKGPQGPAGRDGVQGPVGLP--GPAGPAGSP-----GEDGDKGEIGEPGQ 1097 Query: 494 QCSLQDMMVHQHGPRGVVRGPPPPYQMTPSEGWAPGGTEPFSDG-INMPHSLPPRGMAPH 552 + S D ++GP GPP + G A G EP G M G Sbjct: 1098 KGSKGDK--GENGP----PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGF 1151 Query: 553 PNMPGSQMRLPGFAGMINSEMEGPNVPNPASRPGLSGVSWPDDVPKIPDGRNFPPGQGIF 612 P PG + L G G + E +V P PG G P P DG PPG + Sbjct: 1152 PGPPG-PIGLQGLPGPPGEKGENGDV-GPMGPPGPPGPRGPQG-PNGADGPQGPPG-SVG 1207 Query: 613 SGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPG 672 S G GE+ + E PPG A G P +R + Sbjct: 1208 SVGGVGEK-------------GEPGEAGNPGPPGEAGVG----------GPKGERGEKGE 1244 Query: 673 NNPIFPRIPVEGPLSPSRGDFPKGIPPQMG----PGRELEFGMV-PSGMKGDVNLNVNMG 727 P P G P D PKG P +G PG E G G+ GD + + G Sbjct: 1245 AGPPGAAGP-PGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPG 1303 Query: 728 SNSQMIPQKMREAGAGPEEMLKLRPG--GSDMLPAQQKMVPLPFGEHPQQEYG-MGPRPF 784 P EAG + PG G++ ++ E P + G +GP Sbjct: 1304 QPGP--PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGP--- 1358 Query: 785 LPMSQGPGSN---SGLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGL 841 QGP GLR + P+G + PP P+ P P GL Sbjct: 1359 ----QGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLP-----------GL 1403 Query: 842 GRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGMLAGPAA 901 P G + H PG+ L P Q + G P G SP G + GPA Sbjct: 1404 KGDP---GSKGEKGH-PGLIGLIGPPGEQGEKGDRGLP-GTQGSPGAKGD--GGIPGPAG 1456 Query: 902 AASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMAS 958 PP L P K + PA G + P PP SPG P PL + S Sbjct: 1457 PLGPPGPPGL-PGPQGPKGNKGSTGPAGQKGDSGLPGPP-GSPGPPGEVIQPLPILS 1511 Score = 35.0 bits (79), Expect = 0.52 Identities = 97/409 (23%), Positives = 128/409 (31%), Gaps = 87/409 (21%) Query: 231 PKPLPQQ--PPAPANQDQNSSQNTRLQPTPPIPAPAPKPAAPPRPLDRESPGVENKL--I 286 P P+ Q P P + +N P PP P P P + PG + + Sbjct: 1155 PGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGP--QGPPGSVGSVGGV 1212 Query: 287 PSVGSPASS-TPLPPDGTGPNSTPNNR----------AVTPVSQGSNSSSADPKAPPPPP 335 G P + P PP G R A P PK P P Sbjct: 1213 GEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1272 Query: 336 VSSGEPPTLGE----NPDGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQS-GGPQQ 390 G+P GE DG+ ++ E + P + G GP Sbjct: 1273 GFPGDPGPPGEPGPAGQDGVGGDKGEDGD--------------PGQPGPPGPSGEAGPPG 1318 Query: 391 NPGVLDGPQKK-PEGPIQAMMAQSQSLGKGP-------GPRTDVGAPFGPQGHRDVPFSP 442 PG P EG A+ ++ +GP GP+ G P GP+G R +P Sbjct: 1319 PPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKP-GPEGLRGIPGPV 1377 Query: 443 DEMVPPSMNSQSGTIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMV 502 E P Q G GP M P + LK EK ++ Q Sbjct: 1378 GEQGLPGAAGQDGPPGP-----MGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG--- 1429 Query: 503 HQHGPRGVVRGPPPPYQMTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPGSQMRL 562 + G RG+ P +PG DG +P P G P +PG Q Sbjct: 1430 -EKGDRGL-----------PGTQGSPGAK---GDG-GIPGPAGPLGPPGPPGLPGPQ--- 1470 Query: 563 PGFAGMINSEMEGPNVPNPASRPGLSGVSWPDDVPKIPDGRNFPPGQGI 611 G G S PA + G SG+ P P PPG+ I Sbjct: 1471 -GPKGNKGS-------TGPAGQKGDSGLPGPPGSPG-------PPGEVI 1504 >gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo sapiens] Length = 1806 Score = 112 bits (280), Expect = 3e-24 Identities = 264/1034 (25%), Positives = 347/1034 (33%), Gaps = 166/1034 (16%) Query: 506 GPRGVVRGPPPPYQMTPSEG--WAPGGT----EPFSDGINMPHSLP----------PRGM 549 GPRGV +GPP P G A GG EP + G LP RG Sbjct: 562 GPRGV-QGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGP 620 Query: 550 APHPNMPGSQ-MR----------LPGFAGMINSEMEGPN-VPNPASRPGLSGVSWPDDVP 597 P PG MR LPG AG + GP P +PG++GV P P Sbjct: 621 QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRG--LLGPRGTPGAPGQPGMAGVDGPPG-P 677 Query: 598 KI---PDGRNFPPGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRP 654 K P G PPGQ GP + P PQG EK PG+A G+ P Sbjct: 678 KGNMGPQGEPGPPGQQGNPGP---QGLPGPQGPIGPP-----GEKGPQGKPGLA--GL-P 726 Query: 655 SMEMNRMIPGSQRHM-EPGN-NPIFPRIPV--EGPLSPSRGDFPKGIPPQMGPGRELEFG 710 + PG + E G P P+ P+ GP D +G+ G E F Sbjct: 727 GADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGF- 785 Query: 711 MVPSGMKGDVNLNVNMGSNSQMIPQKMREAGAGPEEMLKLR--PGGSDMLPAQQKMVPLP 768 G KGD+ L + G Q+ P+ + GP+ PG S + K+ Sbjct: 786 ---PGFKGDMGLKGDRGEVGQIGPRG-EDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPG 841 Query: 769 FGEHPQQEYGMGPRPFLPMSQGPGSNS-----------GLRNLREPIGPDQRTNSRLSHM 817 +P ++ GP+ PG+N G R R P GP +R Sbjct: 842 LPGYPGRQ---GPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTG 898 Query: 818 PPLPLNPSSNPTSLNTAPPVQRGLGRKPLDISVAGSQ--VHSPGINPLKSPTMHQVQSPM 875 P P S PP +RG + G + PG + L + ++ Sbjct: 899 KPGPKGTSGGDGP--PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGF 956 Query: 876 LGSPS----GNLKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSP 931 G G + PQ P+ G + G PP G K + P P Sbjct: 957 QGKTGPPGPGGVVGPQGPTGETGPI-GERGHPGPPGPP--GEQGLPGAAGKEGAKGDPGP 1013 Query: 932 GWTSSPKPPLQSPGIPPNHKAPLTMASPAMLGNVESGGPPPPTASQPASVNIPGSLPSST 991 S P G P P +P + G GPP P S GS ++ Sbjct: 1014 QGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER----GSAGTAG 1069 Query: 992 PYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMN 1051 P +P P Q P + + P D ++ + PA SP Sbjct: 1070 PIGLPGRPG-PQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1128 Query: 1052 NM---PGMGINTQNPRISGPN--PVVPMPTLSP--------------MGMTQPLSHSNQM 1092 PG + + +GP P + P +P GM Sbjct: 1129 GEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGAR 1188 Query: 1093 PSPNAVGPNIPPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVP 1152 P GP I G+P PG N +G P P+G G P G Q PP V Sbjct: 1189 GFPGPPGP-IGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQG-PNGADGPQGPPGSVG 1246 Query: 1153 FPHNGPSGGQGSFPGGMGFPGE----GPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLG 1208 G+ G G PGE GP G ++ A PG G P G Sbjct: 1247 SVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKG 1306 Query: 1209 NSMPSVFTDPDLQEVIRPGATGIPEFDLSRIIPSEK-----PSQTLQYFPRGEV--PGRK 1261 N P F PG G P + +K P Q P GE PG Sbjct: 1307 NPGPVGFPGD-------PGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPP 1359 Query: 1262 QPQGPGPGFSHMQGMMGEQAPRMGLALPGMGGP-GPVGTPDIPLGTAPSMPGHNPMR--P 1318 +GP PG + +G GE+ + G G GPVG P P G PG +R P Sbjct: 1360 GKRGP-PGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVG-PQGPAGK----PGPEGLRGIP 1413 Query: 1319 PAFLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAAA--------VGMI--PGK-----DR 1363 +QG+ G + P PG P L +P + +G+I PG+ DR Sbjct: 1414 GPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDR 1473 Query: 1364 GPAGLYTHPG------------PVGSPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGM 1411 G G PG P+G PG + G GP+ N P G D G+ Sbjct: 1474 GLPGTQGSPGAKGDGGIPGPAGPLGPPGPP-GLPGPQGPKGN---KGSTGPAGQKGDSGL 1529 Query: 1412 GGFSQGPGNPGNMM 1425 G PG PG ++ Sbjct: 1530 PGPPGSPGPPGEVI 1543 Score = 107 bits (268), Expect = 6e-23 Identities = 280/1140 (24%), Positives = 371/1140 (32%), Gaps = 189/1140 (16%) Query: 420 PGPRTDVG--APFGPQGHRDVPFSPDEMVP---PSMNSQSGTIGPDHLDHMTPEQIAWLK 474 PGP G P G QG P P + P P + G GP M P + Sbjct: 444 PGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDG 503 Query: 475 LQQEFYEEKRRKQEQVVVQQCSL----------------------------QDMMVHQHG 506 + + Q Q ++QQ + + G Sbjct: 504 SKGPTI-SAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQG 562 Query: 507 PRGVVRGPPPPYQMTPSEG--WAPGGT----EPFSDGINMPHSLP----------PRGMA 550 PRG V+GPP P G A GG EP + G LP RG Sbjct: 563 PRG-VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQ 621 Query: 551 PHPNMPGSQ-MR----------LPGFAGMINSEMEGP-NVPNPASRPGLSGVSWPDDVPK 598 P PG MR LPG AG + GP P +PG++GV P PK Sbjct: 622 GPPGPPGDDGMRGEDGEIGPRGLPGEAG--PRGLLGPRGTPGAPGQPGMAGVDGPPG-PK 678 Query: 599 ---IPDGRNFPPGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRPS 655 P G PPGQ GP + P PQG EK PG+A G+ P Sbjct: 679 GNMGPQGEPGPPGQQGNPGP---QGLPGPQGPIGPP-----GEKGPQGKPGLA--GL-PG 727 Query: 656 MEMNRMIPG--SQRHMEPGNNPIFPRIPV--EGPLSPSRGDFPKGIPPQMGPGRELEFGM 711 + PG Q + P P+ P+ GP D +G+ G E F Sbjct: 728 ADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGF-- 785 Query: 712 VPSGMKGDVNLNVNMGSNSQMIPQ-----KMREAGAGPEEMLKLRPGGSDMLPAQQKMVP 766 G KGD+ L + G Q+ P+ + + AGP PG S + K+ Sbjct: 786 --PGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTG----DPGPSGQAGEKGKLGV 839 Query: 767 LPFGEHPQQEYGMGPRPFLPMSQGPGSNS-----------GLRNLREPIGPDQRTNSRLS 815 +P ++ GP+ PG+N G R R P GP +R Sbjct: 840 PGLPGYPGRQ---GPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGP 896 Query: 816 HMPPLPLNPSSNPTSLNTAPPVQRGL--GRKPLDISVAGSQVHSPGINPLKSPTMHQVQS 873 P P S PP +RG + P+ PG + L + ++ Sbjct: 897 TGKPGPKGTSGGDGP--PGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGET 954 Query: 874 PMLGSPS----GNLKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAP 929 G G + PQ P+ G + G PP G K + P Sbjct: 955 GFQGKTGPPGPGGVVGPQGPTGETGPI-GERGHPGPPGPP--GEQGLPGAAGKEGAKGDP 1011 Query: 930 SPGWTSSPKPPLQSPGIPPNHKAPLTMASPAMLGNVESGGPPPPTASQPASVNIPGSLPS 989 P S P G P P +P + G GPP P S GS + Sbjct: 1012 GPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGER----GSAGT 1067 Query: 990 STPYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPS 1049 + P +P P Q P + + P D ++ + PA SP Sbjct: 1068 AGPIGLPGRPG-PQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDG 1126 Query: 1050 MN---NMPGMGINTQNPRISGP--NPVVPMPTLSP--------------MGMTQPLSHSN 1090 PG + + +GP P + P +P GM Sbjct: 1127 DKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEG 1186 Query: 1091 QMPSPNAVGPNIPPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQ 1150 P GP I G+P PG N +G P P+G G P G Q PP Sbjct: 1187 ARGFPGPPGP-IGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQG-PNGADGPQGPPGS 1244 Query: 1151 VPFPHNGPSGGQGSFPGGMGFPGE----GPLGRPSNLPQSSADAALCKPGGPGGPDSFTV 1206 V G+ G G PGE GP G ++ A PG G P Sbjct: 1245 VGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGP 1304 Query: 1207 LGNSMPSVFTDPDLQEVIRPGATGIPEFDLSRIIPSEK-----PSQTLQYFPRGEV--PG 1259 GN P F PG G P + +K P Q P GE PG Sbjct: 1305 KGNPGPVGFPGD-------PGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPG 1357 Query: 1260 RKQPQGPGPGFSHMQGMMGEQAPRMGLALPG-MGGPGPVGTPDIPLGTAPSMPGHNPMR- 1317 +GP PG + +G GE+ + G G GPVG P P G PG +R Sbjct: 1358 PPGKRGP-PGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVG-PQGPAG----KPGPEGLRG 1411 Query: 1318 -PPAFLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAA--------AVGMI-PGKDRGPAG 1367 P +QG+ G + P PG P L +P + +G+I P ++G G Sbjct: 1412 IPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKG 1471 Query: 1368 LYTHPGPVGSPGM-----MMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 PG GSPG + G +GP +P P+G G G G PG Sbjct: 1472 DRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPG 1531 Score = 86.7 bits (213), Expect = 1e-16 Identities = 268/1077 (24%), Positives = 351/1077 (32%), Gaps = 186/1077 (17%) Query: 454 SGTIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQ----DMMV------- 502 SGT P+ ++ + E+ L E Y+ +R+ E + + + D++V Sbjct: 326 SGTNEPNPVEEIFTEEY----LTGEDYDSQRKNSEDTLYENKEIDGRDSDLLVDGDLGEY 381 Query: 503 --HQHGPRGVVRGPPPPYQMTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPGSQM 560 +++ PP + P P T+ IN + +G P + M Sbjct: 382 DFYEYKEYEDKPTSPPNEEFGPG---VPAETDITETSINGHGAYGEKGQKGEPAVVEPGM 438 Query: 561 RLPGFAGMINSE--MEGPNVPNPASRPGLSGVSWPDDVPKIP--DGRNFPPGQGI---FS 613 + G G M P + P PG G P P +P DG PPG + F Sbjct: 439 LVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFR 498 Query: 614 GPGRGERFPNPQGLSEEMFQQQLAEKQLGL--PPG-MAMEGIRPSMEMNRMIPGSQRHM- 669 G G + P E Q L + ++ L PPG M + G RP G++ Sbjct: 499 YGGDGSKGPTISA-QEAQAQAILQQARIALRGPPGPMGLTG-RPGPVGGPGSSGAKGESG 556 Query: 670 EPGNNPIFPRIPVEGPLSPS-----RG----DFPKGIPPQMGPGRELEFGMVPSGMKGDV 720 +PG P PR V+GP P+ RG D +G+P + G + F +P G+ GD Sbjct: 557 DPG--PQGPR-GVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLP-GLPGDK 612 Query: 721 NLNVNMGSNSQMIP---QKMR----EAG-------AGPEEMLKLRPGGSDMLPAQQKMVP 766 G P MR E G AGP +L P G+ P Q M Sbjct: 613 GHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLG--PRGTPGAPGQPGMAG 670 Query: 767 LPFGEHPQQEYGMGPRPFLPMSQGPGSNSGLRNLREPIGPDQRTNSR----LSHMPPL-- 820 + P+ G P P QG GL + PIGP + L+ +P Sbjct: 671 VDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADG 730 Query: 821 -PLNPSSNPTSLN---TAPPVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPML 876 P +P S PP +G P V G+ G+ LK + + Sbjct: 731 PPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGAD----GVRGLKGSKGEKGEDGFP 786 Query: 877 GSPSG-NLKSPQTPSQLAGMLA-----GPAAAASIKSPPVLGSAAASPVHLKSPSLPAPS 930 G LK + G GP A P A L P LP Sbjct: 787 GFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPG-Y 845 Query: 931 PGWTSSPKPPLQSPGIPPNHKAPLTMASPAMLGNVESGGPPPPTASQPASVNIPGSLPSS 990 PG PK PG P + G GP P S+ A P Sbjct: 846 PG-RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKG 904 Query: 991 TP-YTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARS--PNL 1047 T PP P + P F P P PP + P Sbjct: 905 TSGGDGPPGPPGERGPQG--PQGPVGFPGPKGPP---------------GPPGKDGLPGH 947 Query: 1048 PSMNNMPGMGINTQNPRISGPNPVVPMPTLSPMGMTQPLSHSNQMPSPNAVGPNIPPHGV 1107 P G T P GP VV P G T P+ P G G+ Sbjct: 948 PGQRGETGFQGKTGPP---GPGGVV--GPQGPTGETGPIGERGHPGPPGPPG----EQGL 998 Query: 1108 PMGPGLMSHNPIMGHGSQEPPMVPQGRMGFP--QGFPPVQSPPQQVPFPHNGPSGGQG-- 1163 P G G P G GFP +G P Q P G GG+G Sbjct: 999 PGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP--------GLKGGEGPQ 1050 Query: 1164 SFPGGMGFPGE-------GPLGRPSNL-PQSSADAALCK-------PGGPGGPDSFT--- 1205 PG +G PGE GP+G P PQ A K P GP G D Sbjct: 1051 GPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPV 1110 Query: 1206 -VLGNSMP--SVFTDPDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQ 1262 + G + P S D D E+ PG G + D P P +G V Sbjct: 1111 GLPGPAGPAGSPGEDGDKGEIGEPGQKG-SKGDKGENGPPGPPGL------QGPVGAPGI 1163 Query: 1263 PQGPG-PGFSHMQGMMGEQAPRMGLALPGMGGPGPVGTPDIPLGTAPSMPGHN----PMR 1317 G G PG QGM G++ P G PGP+G +P P G N PM Sbjct: 1164 AGGDGEPGPRGQQGMFGQKGDEGARGFP--GPPGPIGLQGLP--GPPGEKGENGDVGPMG 1219 Query: 1318 PPAFLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAAAVGMIPG-KDRGPAGLYTHPGPVG 1376 PP G GP P + P P +VG + G ++G G +PGP G Sbjct: 1220 PPG--PPGPRGP----QGPNGADGP------QGPPGSVGSVGGVGEKGEPGEAGNPGPPG 1267 Query: 1377 SPGM-----------MMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 G+ G GP P P+G VG G PG PG Sbjct: 1268 EAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPG 1324 Score = 60.1 bits (144), Expect = 1e-08 Identities = 183/717 (25%), Positives = 234/717 (32%), Gaps = 121/717 (16%) Query: 261 PAPAPKPAAPPRPLDRESPGVENKLIPSVGSPASSTPLPPDGTGPNSTPNNRAVTPVSQG 320 P P K P P R G + K G P + P G + P P Sbjct: 936 PGPPGKDGLPGHPGQRGETGFQGK----TGPPGPGGVVGPQGPTGETGPIGERGHP---- 987 Query: 321 SNSSSADPKAPPPPPVSSGEPPTLGEN-------PDGLSQEQLEHRERSLQTLRDIQRML 373 PP PP G P G+ P G+S + R Sbjct: 988 ---------GPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRG----------- 1027 Query: 374 FPDEKEFTGAQSGGPQQNPGVLDGPQKKPEGPIQAMMAQSQSLGKGPGPRTDVGAPFGPQ 433 FP E+ GAQ G P G +GPQ P GP+ + + + GP P GP Sbjct: 1028 FPGERGLPGAQ-GAPGLKGG--EGPQGPP-GPVGSPGERGSAGTAGPIGLPGRPGPQGPP 1083 Query: 434 GHRDVPFSPDEMVPPSMNSQSGTIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQ 493 G +P E P + G GP L P A E+ + + Q Sbjct: 1084 GPAGEKGAPGEKGPQGPAGRDGVQGPVGLP--GPAGPAGSP-----GEDGDKGEIGEPGQ 1136 Query: 494 QCSLQDMMVHQHGPRGVVRGPPPPYQMTPSEGWAPGGTEPFSDG-INMPHSLPPRGMAPH 552 + S D ++GP GPP + G A G EP G M G Sbjct: 1137 KGSKGDK--GENGP----PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGF 1190 Query: 553 PNMPGSQMRLPGFAGMINSEMEGPNVPNPASRPGLSGVSWPDDVPKIPDGRNFPPGQGIF 612 P PG + L G G + E +V P PG G P P DG PPG + Sbjct: 1191 PGPPG-PIGLQGLPGPPGEKGENGDV-GPMGPPGPPGPRGPQG-PNGADGPQGPPG-SVG 1246 Query: 613 SGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPG 672 S G GE+ + E PPG A G P +R + Sbjct: 1247 SVGGVGEK-------------GEPGEAGNPGPPGEAGVG----------GPKGERGEKGE 1283 Query: 673 NNPIFPRIPVEGPLSPSRGDFPKGIPPQMG----PGRELEFGMV-PSGMKGDVNLNVNMG 727 P P G P D PKG P +G PG E G G+ GD + + G Sbjct: 1284 AGPPGAAGP-PGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPG 1342 Query: 728 SNSQMIPQKMREAGAGPEEMLKLRPG--GSDMLPAQQKMVPLPFGEHPQQEYG-MGPRPF 784 P EAG + PG G++ ++ E P + G +GP Sbjct: 1343 QPGP--PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGP--- 1397 Query: 785 LPMSQGPGSN---SGLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGL 841 QGP GLR + P+G + PP P+ P P GL Sbjct: 1398 ----QGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLP-----------GL 1442 Query: 842 GRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGMLAGPAA 901 P G + H PG+ L P Q + G P G SP G + GPA Sbjct: 1443 KGDP---GSKGEKGH-PGLIGLIGPPGEQGEKGDRGLP-GTQGSPGAKGD--GGIPGPAG 1495 Query: 902 AASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMAS 958 PP L P K + PA G + P PP SPG P PL + S Sbjct: 1496 PLGPPGPPGL-PGPQGPKGNKGSTGPAGQKGDSGLPGPP-GSPGPPGEVIQPLPILS 1550 Score = 35.0 bits (79), Expect = 0.52 Identities = 97/409 (23%), Positives = 128/409 (31%), Gaps = 87/409 (21%) Query: 231 PKPLPQQ--PPAPANQDQNSSQNTRLQPTPPIPAPAPKPAAPPRPLDRESPGVENKL--I 286 P P+ Q P P + +N P PP P P P + PG + + Sbjct: 1194 PGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGP--QGPPGSVGSVGGV 1251 Query: 287 PSVGSPASS-TPLPPDGTGPNSTPNNR----------AVTPVSQGSNSSSADPKAPPPPP 335 G P + P PP G R A P PK P P Sbjct: 1252 GEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV 1311 Query: 336 VSSGEPPTLGE----NPDGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQS-GGPQQ 390 G+P GE DG+ ++ E + P + G GP Sbjct: 1312 GFPGDPGPPGEPGPAGQDGVGGDKGEDGD--------------PGQPGPPGPSGEAGPPG 1357 Query: 391 NPGVLDGPQKK-PEGPIQAMMAQSQSLGKGP-------GPRTDVGAPFGPQGHRDVPFSP 442 PG P EG A+ ++ +GP GP+ G P GP+G R +P Sbjct: 1358 PPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKP-GPEGLRGIPGPV 1416 Query: 443 DEMVPPSMNSQSGTIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMV 502 E P Q G GP M P + LK EK ++ Q Sbjct: 1417 GEQGLPGAAGQDGPPGP-----MGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG--- 1468 Query: 503 HQHGPRGVVRGPPPPYQMTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPGSQMRL 562 + G RG+ P +PG DG +P P G P +PG Q Sbjct: 1469 -EKGDRGL-----------PGTQGSPGAK---GDG-GIPGPAGPLGPPGPPGLPGPQ--- 1509 Query: 563 PGFAGMINSEMEGPNVPNPASRPGLSGVSWPDDVPKIPDGRNFPPGQGI 611 G G S PA + G SG+ P P PPG+ I Sbjct: 1510 -GPKGNKGS-------TGPAGQKGDSGLPGPPGSPG-------PPGEVI 1543 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 112 bits (279), Expect = 3e-24 Identities = 319/1347 (23%), Positives = 428/1347 (31%), Gaps = 248/1347 (18%) Query: 230 DPKPLPQQPPAPANQDQNSSQNTRLQPTPPIPAPAPKPAAPPRPLDRESPGVENKL---- 285 DP+ L ++P P+ + +++ T P P P A P P E G E + Sbjct: 282 DPEDLGKEP-TPSKKPVEAAKETTEVPEELTPTPTE---AAPMPETSEGAGKEEDVGIGD 337 Query: 286 IPSVGSPASSTPLPPD----GTGPNST-----PNNRAVTPVSQGSNSSSADPKAPPPPPV 336 V S TP P D G G + P A P S S+S++P APPP Sbjct: 338 YDYVPSEDYYTPSPYDDLTYGEGEENPDQPTDPGAGAEIPTSTADTSNSSNP-APPP--- 393 Query: 337 SSGEPPTLGENPDGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPGVLD 396 GE D L E E +T+R++ + + T + S P D Sbjct: 394 --------GEGADDLEGEFTE------ETIRNLDENYYDPYYDPTSSPSEIGPGMPANQD 439 Query: 397 GPQKKPEGPIQAMMAQSQSLGKGPGPRTDVGAPFGPQGHRDVPFSPDEMVPPSMNSQSGT 456 + GP + + PG + P GP+G +P P M P G Sbjct: 440 TIYEGIGGPRGEKGQKGEPAIIEPGMLIE--GPPGPEGPAGLPGPPGTMGPTGQVGDPGE 497 Query: 457 IGP------DHLDHMTPEQIAWLKLQQEF-----------YEEKRRKQEQVVVQQCSL-- 497 GP D + L L F + Q Q ++QQ L Sbjct: 498 RGPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLAL 557 Query: 498 --------------------------QDMMVHQHGPRGVVRGPPPPYQMTPSEGWA---- 527 + V GPRG V+GPP P G A Sbjct: 558 RGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRG-VQGPPGPAGKPGRRGRAGSDG 616 Query: 528 ----PGGTEPFSD-GINMPHSLPPR-------GMAPHPNMPGSQMRL------------- 562 PG T P D G + LP G + P PG Sbjct: 617 ARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPG 676 Query: 563 -PGFAGMINSEMEGPNVPNPASRPGLSGV-SWPDDVPKI-PDGRNFPPGQGIFSGPGRGE 619 PG G++ +GP P P PG++G+ P + P G PPGQ G + Sbjct: 677 EPGPRGLLGP--KGP--PGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQ---QGNPGAQ 729 Query: 620 RFPNPQGLSEEMFQQQLAEKQLGLP--PGMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIF 677 P PQG + + LG P PGM P PG + G P Sbjct: 730 GLPGPQGAIGPPGE----KGPLGKPGLPGMPGADGPPGHPGKEGPPGE----KGGQGPPG 781 Query: 678 PRIPV--EGPLSPSRGDFPKGIPPQMGPGRELEFGMVPSGMKGDVNLNVNMGS------N 729 P+ P+ GP D +G+ G E F G KGD+ + + G Sbjct: 782 PQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGF----PGFKGDMGIKGDRGEIGPPGPR 837 Query: 730 SQMIPQKMREAGAGPEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPMSQ 789 + P+ + G + L P G + P + P+ G P P + Sbjct: 838 GEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGF---PGFPGAN 894 Query: 790 G-------PGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGLG 842 G PG G R R P GP R P P S PP +RG Sbjct: 895 GEKGGRGTPG-KPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGP--AGPPGERGPN 951 Query: 843 --RKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLG--SPSG--NLKSPQTPSQLAGML 896 + P PG + L + ++ G P G + PQ P+ G + Sbjct: 952 GPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPM 1011 Query: 897 AGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTM 956 G PP G + K + P P P G P + P + Sbjct: 1012 -GERGHPGPPGPP--GEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPV 1068 Query: 957 ASPAMLGNVESGGPPPPTASQ----PASVNIPGSLPSSTPYTMPPEPTLSQNPLSIMMSR 1012 + + GN GPP P S PA P +P PP P + + Sbjct: 1069 GALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQ 1128 Query: 1013 MSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMGINTQNPRISGPNPVV 1072 P+ + + PP + + G P P Sbjct: 1129 -----GPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTG 1183 Query: 1073 PMPTLSPMGMTQPLSHSNQMPSPNA----------VGPNIPP--------HGVPMGPGLM 1114 P P+G P S ++ P P GP P G+P PG Sbjct: 1184 PQ---GPIGQPGP-SGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEK 1239 Query: 1115 SHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPSGGQGSFPGGMGFPGE 1174 +G P P+G G P P Q PP + P G+ G G PGE Sbjct: 1240 GETGDVGQMGPPGPPGPRGPSGAPGADGP-QGPPGGIGNPGAVGEKGEPGEAGEPGLPGE 1298 Query: 1175 ----GPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFT-DPDLQEVIRPGAT 1229 GP G +S A PG G P G+ P F DP P Sbjct: 1299 GGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQ 1358 Query: 1230 GIPEFDLSRIIPSEKPSQTLQYFPRGE-----VPGRKQPQGP-GPGFSHMQGMMGEQAPR 1283 P D +P QT P GE PG++ P GP GP +G GE+ + Sbjct: 1359 DGPPGDKG---DDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGP-----EGRQGEKGAK 1410 Query: 1284 MGLALPG-MGGPGPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMSPAQSTMP 1342 L G G GP+G P G AP PG + +R G+ GP P Sbjct: 1411 GEAGLEGPPGKTGPIG----PQG-APGKPGPDGLR-------GIPGPVGEQGLPGSPGPD 1458 Query: 1343 GQPTLMSNPAAAVGMIPG--KDRGPAGLYTHP---GPVGSPGMM--MSMQGMMGPQQNIM 1395 G P M P +PG D GP G HP G +G PG +G+ GPQ + Sbjct: 1459 GPPGPMGPPG-----LPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGS-- 1511 Query: 1396 IPPQMRPRGMAADVGMGGFSQGPGNPG 1422 P+G G G PG PG Sbjct: 1512 ----SGPKGEQGITGPSGPIGPPGPPG 1534 Score = 105 bits (262), Expect = 3e-22 Identities = 255/983 (25%), Positives = 322/983 (32%), Gaps = 203/983 (20%) Query: 506 GPRGVVR-----GPPPPYQMTPSEGWAPGGTEPFSDGINMPHSLP-PRGMAPHPNMPGSQ 559 GPRG++ GPP P +T +G +P G P P P G +P G Sbjct: 679 GPRGLLGPKGPPGPPGPPGVTGMDG------QPGPKGNVGPQGEPGPPGQQGNPGAQG-- 730 Query: 560 MRLPGFAGMINSEMEGPNVPNPASRPGLSGVSWPDDVPKIPDGRNFPPGQGIFSGPGRGE 619 LPG G I P P +PGL G+ D P P G+ PPG+ GP + Sbjct: 731 --LPGPQGAIGP----PGEKGPLGKPGLPGMPGADGPPGHP-GKEGPPGEKGGQGPPGPQ 783 Query: 620 R---FPNPQGLSEEMFQQQLAEKQLGLP--PGMAMEGIRPSMEMNRMIPGSQRHMEPGNN 674 +P P+G+ A+ GL G E P + + I G + + P Sbjct: 784 GPIGYPGPRGVKG-------ADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPG- 835 Query: 675 PIFPRIPVEGPLSPSRGDFPKGIPPQMGPGRELEFGMVPS--------GMKGDVNLNVNM 726 PR +GP P P G P +GP E VP G KG + Sbjct: 836 ---PR-GEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFP 891 Query: 727 GSNSQMIPQKMREAGAGPEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQQEYGMGPRPFLP 786 G+N + + G G +PG P Q+ P GE GPR + Sbjct: 892 GANGE-------KGGRGTPG----KPG-----PRGQRGPTGPRGER-------GPRG-IT 927 Query: 787 MSQGPGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNT-APPVQRGLGRKP 845 GP NSG P GP P P P+ P PP + GL P Sbjct: 928 GKPGPKGNSGGDG---PAGPPGERG------PNGPQGPTGFPGPKGPPGPPGKDGLPGHP 978 Query: 846 LDISVAGSQVHS-----PGINPLKSPT-----MHQVQSPMLGSPSGN-----------LK 884 G Q + PG+ + PT M + P P G K Sbjct: 979 GQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTK 1038 Query: 885 SPQTPSQLAGM--------------LAGPAAAASIKS---PPVLGSAAASPVHLKSPSLP 927 P+ L G L GP A +K PP A SP + P+ Sbjct: 1039 GDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGE-RGPAGA 1097 Query: 928 APSPGWTSSPKPPLQSPGIP------PNHKAPLTMAS-PAMLGNVESGGP-----PPPTA 975 A G P P Q P P P K P A + G V GP PP Sbjct: 1098 AGPIGIPGRPGP--QGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGED 1155 Query: 976 SQPASVNIPGSLPSSTPYTM--PPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVA 1033 + PG S PP PT Q P+ + P Sbjct: 1156 GDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIG-----QPGPSGADGEPGPRGQQGLFG 1210 Query: 1034 SSDDDSP-----PARSPNLPSMNNMPG-MGINTQNPRISGPNPVVPMPTLSPMGMTQPLS 1087 D+ P P L + PG G ++ P P P G P Sbjct: 1211 QKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQG 1270 Query: 1088 HSNQMPSPNAVG----------PNIPPHGVPMGP-GLMSHNPIMGHGSQEPPMVPQGRMG 1136 + +P AVG P +P G P GP G G P P+G G Sbjct: 1271 PPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPG 1330 Query: 1137 F--------PQGFPPVQSPPQQV-PFPHNGPSGGQGSF--PGGMGFPGEGPLGRPSNLPQ 1185 P GFP PP + P +GP G +G PG G PG P+ P Sbjct: 1331 DDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPG------PTGEPG 1384 Query: 1186 SSADAALCKPGGPGGPDSFTVLGNSMPSVFTD--PDLQEVIRP-GATGIPEFDLSRIIPS 1242 S P GP GP+ + + P I P GA G P D R IP Sbjct: 1385 PSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPG 1444 Query: 1243 EKPSQTLQYFPRGEVPGRKQPQGP-GP-GFSHMQGMMGEQAPRMGLALPGM----GGPGP 1296 Q L PG P GP GP G + G+ G+ P+ PG+ G PG Sbjct: 1445 PVGEQGL--------PGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGE 1496 Query: 1297 VGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAAAVG 1356 G +PG P +QG+ GP + P +PG P P A G Sbjct: 1497 QGEKG-----DRGLPGPQGSSGPKG-EQGITGPSGPIGPPGPPGLPGPP----GPKGAKG 1546 Query: 1357 MIPGKDRGPAGLYTHPGPVGSPG 1379 GP G HPGP G PG Sbjct: 1547 S--SGPTGPKGEAGHPGPPGPPG 1567 Score = 60.5 bits (145), Expect = 1e-08 Identities = 187/768 (24%), Positives = 235/768 (30%), Gaps = 164/768 (21%) Query: 241 PANQDQNSSQNTRLQPTPP-IPAPAPKPAAPPRPLDRESPGVENKLIPSVGSPASSTPLP 299 P + N Q P P P P K P P R G + K P P P Sbjct: 945 PGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGP---------PGP 995 Query: 300 PDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGEPPTLGEN-------PDGLS 352 P GP P + PP PP G P G+ P GL Sbjct: 996 PGVVGPQG--------PTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLP 1047 Query: 353 QEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSG-------GPQQNPGVLDGP-QKKPEG 404 + R FP ++ G GP PG P ++ P G Sbjct: 1048 GKDGPPGLRG-----------FPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAG 1096 Query: 405 PIQAMMAQSQSLGKGP-GPRTDVGAPF--GPQGH--RD-------VPFSPDEMVPPSMNS 452 + + +GP GP + GAP GPQG RD +P + PP + Sbjct: 1097 AAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDG 1156 Query: 453 QSGTIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVR 512 G IG P Q K K EQ Q + Q GP G Sbjct: 1157 DKGEIGE-------PGQKG----------SKGDKGEQGPPGPTGPQGP-IGQPGPSGADG 1198 Query: 513 GPPPPYQMTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPGSQMRLPGFAGMINSE 572 P P Q G F P P G+ P PG + G G + + Sbjct: 1199 EPGPRGQQGLFGQKGDEGPRGF------PGPPGPVGLQGLPGPPGEK----GETGDVG-Q 1247 Query: 573 MEGPNVPNPASRPGLSGVSWPDDVPKIPDGRNFPPGQGIFSGPGRGERFPNPQGLSEEMF 632 M P P P G G DG PPG G G NP + E+ Sbjct: 1248 MGPPGPPGPRGPSGAPGA----------DGPQGPPG-------GIG----NPGAVGEKGE 1286 Query: 633 QQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIFPRIPVEGPLSPSRGD 692 + E PG+ EG P + R G P GP P D Sbjct: 1287 PGEAGE------PGLPGEGGPPGPKGERGEKGESGPSGAAGPP--------GPKGPPGDD 1332 Query: 693 FPKGIPPQMG----PGRELEFGMV----PSGMKGDVNLNVNMGSNSQMIPQKMREAGAG- 743 PKG P +G PG E G P G KGD GS P E G Sbjct: 1333 GPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGS-----PGPTGEPGPSG 1387 Query: 744 -PEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQQEYG-MGPRPFLPMSQGPGSNSGLRNLR 801 P + P G + ++ E P + G +GP+ P GP GLR + Sbjct: 1388 PPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQG-APGKPGP---DGLRGIP 1443 Query: 802 EPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLDISVAGSQVHSPGIN 861 P+G S PP P+ P P + P G + H PG+ Sbjct: 1444 GPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGP--------------KGEKGH-PGLI 1488 Query: 862 PLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGM--LAGPAAAASIKSPPVLGSAAASPV 919 L P Q + G P PQ S G + GP+ PP L P Sbjct: 1489 GLIGPPGEQGEKGDRGLP-----GPQGSSGPKGEQGITGPSGPIGPPGPPGL-PGPPGPK 1542 Query: 920 HLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMASPAMLGNVES 967 K S P G P PP PG P PL + + N+++ Sbjct: 1543 GAKGSSGPTGPKGEAGHPGPP-GPPGPPGEVIQPLPIQASRTRRNIDA 1589 Score = 40.8 bits (94), Expect = 0.009 Identities = 66/244 (27%), Positives = 85/244 (34%), Gaps = 43/244 (17%) Query: 233 PLPQQPPAPANQD-------------QNSSQNTRLQPTPPIPAPAPKPAAPPRPLDRESP 279 P P P PA QD Q S +P P P P P P R+ Sbjct: 1347 PGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGE 1406 Query: 280 GVENKLIPSVGSPASSTPLPPDGTGPNSTPNN-RAVT-PVSQGSNSSSADPKAPPPPPVS 337 G P + P+ P G P+ R + PV + S P PP P Sbjct: 1407 KGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGP 1466 Query: 338 SGEPPTLGENPD----------GLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSG- 386 G P G++ GL E E+ + L Q P ++ SG Sbjct: 1467 PGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGP 1526 Query: 387 -GPQQNPGVLDGPQKKPEGPIQAMMAQSQSLGKGP-GPRTDVGAPFGPQGHRDVPFSPDE 444 GP PG L GP P+G A+ S GP GP+ + G P GP G P P E Sbjct: 1527 IGPPGPPG-LPGP-PGPKG------AKGSS---GPTGPKGEAGHP-GPPG---PPGPPGE 1571 Query: 445 MVPP 448 ++ P Sbjct: 1572 VIQP 1575 Score = 35.4 bits (80), Expect = 0.40 Identities = 38/156 (24%), Positives = 52/156 (33%), Gaps = 31/156 (19%) Query: 1296 PVGTPDIPLGTAPSMPGHNPMRPPAF----------------LQQGMMGPHHRMMSPAQS 1339 P +IP TA + NP PP L + P++ S Sbjct: 370 PGAGAEIPTSTADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDENYYDPYYDPTSSPSE 429 Query: 1340 TMPGQPTLMSNPAAAVGMIPGKDRGPAG----------LYTHPGPVGSPGMMMSMQGMMG 1389 PG P +G P ++G G + PGP G G+ G MG Sbjct: 430 IGPGMPANQDTIYEGIGG-PRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLP-GPPGTMG 487 Query: 1390 PQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPGNMM 1425 P + P + P G G+ G PG PG M+ Sbjct: 488 PTGQVGDPGERGPPGRP---GLPGADGLPGPPGTML 520 Score = 31.2 bits (69), Expect = 7.5 Identities = 22/79 (27%), Positives = 31/79 (39%), Gaps = 1/79 (1%) Query: 12 PSGNTQSSPKSKQEVMVRPPTVMSPSGNPQLDSKFSNQGKQGGSASQSQPSPCDSKSGGH 71 P G T + + PP G P L K +G G + + P + G Sbjct: 1001 PQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLR-GFP 1059 Query: 72 TPKALPGPGGSMGLKNGAG 90 + LPGP G++GLK G Sbjct: 1060 GDRGLPGPVGALGLKGNEG 1078 Score = 30.8 bits (68), Expect = 9.7 Identities = 20/61 (32%), Positives = 25/61 (40%), Gaps = 1/61 (1%) Query: 30 PPTVMSPSGNPQLDSKFSNQGKQGGSASQSQPSPCDSKSGGHTPKALPGPGGSMGLKNGA 89 PP M P G P L +G++G P + G + LPGP GS G K Sbjct: 1460 PPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGP-PGEQGEKGDRGLPGPQGSSGPKGEQ 1518 Query: 90 G 90 G Sbjct: 1519 G 1519 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 106 bits (265), Expect = 1e-22 Identities = 306/1242 (24%), Positives = 400/1242 (32%), Gaps = 196/1242 (15%) Query: 258 PPIPAPAPKPAAPPRPLDRES-PGVENKLIPSVGSPASSTPLPPDGTGPNSTPNNRAVTP 316 P P + P P ++ PG ++ G P P G + P Sbjct: 87 PICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAP 146 Query: 317 VSQGSNSSSADPKAPPPP-PVSSGEPPTLGENPDGLSQEQLEHRERSLQTLRDIQRMLFP 375 +G + P P PP P PP LG N + + Q L +Q + P Sbjct: 147 GPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQ-LGVMQGPMGP 205 Query: 376 DEKEFTGAQSGGP-----QQNPGV-----LDGPQ--KKPEGPIQAMMAQSQSLGKGPGPR 423 +G P Q NPG + GP + P GP GK PG Sbjct: 206 MGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGP-PGKPGDDGEAGK-PGKA 263 Query: 424 TDVGAPFGPQGHRDVPFSPD------------------EMVPPSMNSQSGTIGPDHLDHM 465 + G P GPQG R P +P E P + +SG+ G ++ Sbjct: 264 GERGPP-GPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPG----ENG 318 Query: 466 TPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPPPPY------Q 519 +P + L E + + Q GP G GP P + Sbjct: 319 SPGPMGPRGLPGE--RGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGE 376 Query: 520 MTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPN---MPGSQ--MRLPGFAGMINSEME 574 P+ P G + P S P G + +P +PG++ PG AG Sbjct: 377 AGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAG------- 429 Query: 575 GPNVPNPASRPGLSGVSWPDDVPKIPDGRNFPPGQGIFSGPG--RGERFP-NPQGLSEEM 631 P P P PG G + P P G+ PG F G +GE P PQG Sbjct: 430 APGFPGPRGPPGPQGATGPLG----PKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPA 485 Query: 632 FQQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIFPRIPVEGPLSPSRG 691 ++ + G P G+ G P E R PG++ PG + + G PS Sbjct: 486 GEEGKRGAR-GEPGGVGPIG--PPGE--RGAPGNRGF--PGQDGLAGPKGAPGERGPSGL 538 Query: 692 DFPKGIPPQMGPGRELEFGMVPSGMKGDVNLNVNMGSNSQMIPQKMREAGAGPEEMLKLR 751 PKG PGR E G+ G +G + G ++ P P E + Sbjct: 539 AGPKGANGD--PGRPGEPGL--PGARGLTGRPGDAGPQGKVGPS------GAPGEDGRPG 588 Query: 752 PGGSDMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPMSQG----PGSNSGLRNLREPIGPD 807 P G Q ++ P + E G LP + G PG + G P GP Sbjct: 589 PPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKD-GETGAAGPPGPA 647 Query: 808 QRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLDISVAGSQVHSPGINPLKSPT 867 R P P P PP G G KP D V G + +PG L P Sbjct: 648 GPAGERGEQGAPGPSGFQGLP-----GPPGPPGEGGKPGDQGVPG-EAGAPG---LVGPR 698 Query: 868 MHQVQSPMLGSPSGNLKSPQTPSQLAGM--------LAGPAAAASIKSPPVLGSAAASPV 919 + GSP + Q P L G +GPA + PP L P Sbjct: 699 GERGFPGERGSPGA--QGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGL---QGMPG 753 Query: 920 HLKSPSLPAPSPGWTS-SPKPPLQSPGIPPNHKAPLTMASPAMLG-NVESG--GPPPPTA 975 + + P K P +PG + P G N E G GPP P Sbjct: 754 ERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAG 813 Query: 976 SQPASVNIPGSLPSSTPYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASS 1035 S A P T PP P + FA P Sbjct: 814 SAGAR-----GAPGERGETGPPGP--------------AGFAGPPGA------------- 841 Query: 1036 DDDSPPARSPNLPSMNNMPGMGINTQNPRISGPNPVVPMPTLSPMGMTQPLSHSNQMPSP 1095 D P A+ + Q P P P P P G P Sbjct: 842 -DGQPGAKGEQGEAGQKGDAGAPGPQGPS-GAPGPQGPTGVTGPKGARGAQGPPGATGFP 899 Query: 1096 NAVGPNIPP--HGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPF 1153 A G PP +G P PG + G P GR G P P P ++ Sbjct: 900 GAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEP 959 Query: 1154 PHNGPSGGQGSFPGGMGFPGE-GPLGRPSN--------LPQSSADAALCKPGGPGGPDSF 1204 +GPSG +G PG G G+ G +G P LP S + K G PG Sbjct: 960 GDDGPSGAEGP-PGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPG--KQGAPGASGDR 1016 Query: 1205 TVLGNSMPSVFTDP--DLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQ 1262 G P T P + PGA G P D + + + RGE Sbjct: 1017 GPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGD----------RGETGAVGA 1066 Query: 1263 PQGPGP-GFSHMQGMMGEQAPRMGLALPGMGGP-GPVGTPDIPLGTAPSMPGHNPMRPPA 1320 P PGP G G G+Q R G GP GP G I P P Sbjct: 1067 PGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPG- 1125 Query: 1321 FLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGLYTHPGPVGSPGM 1380 ++G+ G HR + Q +PG P + A+ P RGP PGPVG G Sbjct: 1126 --ERGLKG--HRGFTGLQG-LPGPPGPSGDQGASGPAGPSGPRGP------PGPVGPSGK 1174 Query: 1381 MMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 G+ GP + PP PRG + + G G PG PG Sbjct: 1175 D-GANGIPGP----IGPPG--PRGRSGETGPAGPPGNPGPPG 1209 Score = 55.8 bits (133), Expect = 3e-07 Identities = 223/957 (23%), Positives = 307/957 (32%), Gaps = 154/957 (16%) Query: 9 RSSPSGNTQSSPKSKQEVMVRPPTVMSPSGNPQLDSKFSNQGKQGGSASQSQPSPCDSKS 68 R+ P+G + Q PP + P+G P +G+ G P+ Sbjct: 334 RTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAG-------PTGARGPE 386 Query: 69 GGHTPKALPGPGGSMGLKNGAGN-------GAKGKGKRERSISADSFD--------QRDP 113 G P+ PG GS G +GN GAKG A F Q Sbjct: 387 GAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGAT 446 Query: 114 GTPNDDSDIKECNSADHIKSQDSQHTPHSMTPSNATAP------RSSTPSHGQTTATEPT 167 G E A Q + P P A P R + G P Sbjct: 447 GPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPP 506 Query: 168 PAQKTPAKVVYVFSTEMANKAAEAVLKGQVETIVSFHIQNISNNKTERSTAPLNTQISAL 227 + P + +A +G + N + P ++ Sbjct: 507 GERGAPGNRGFPGQDGLAGPKGAPGERGP-SGLAGPKGANGDPGRPGEPGLPGARGLTGR 565 Query: 228 RNDPKPLPQQPPAPANQDQN-----SSQNTRLQP-TPPIPAPAPKPAAPPRPLDRESPGV 281 D P + P+ A + Q R QP P P P + ++ PG Sbjct: 566 PGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGA 625 Query: 282 EN-KLIPSVGSPASSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGE 340 + +P + PP GP + + G + P PP PP G+ Sbjct: 626 PGLRGLPGKDGETGAAG-PPGPAGPAGERGEQG----APGPSGFQGLP-GPPGPPGEGGK 679 Query: 341 PPTLGENPDGLSQEQLEHR-ERSLQTLRDIQRMLFPDEKEFTGAQS-GGPQQNPGV--LD 396 P G + + + R ER FP E+ GAQ GP+ PG D Sbjct: 680 PGDQGVPGEAGAPGLVGPRGERG-----------FPGERGSPGAQGLQGPRGLPGTPGTD 728 Query: 397 GPQ--KKPEGP--------IQAMMAQSQSLG-KGP-GPRTDVG----------------- 427 GP+ P GP +Q M + + G GP G R DVG Sbjct: 729 GPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLT 788 Query: 428 APFGPQGHRDVPFSPDEMVPPSMNSQSGTIG-PDHLDHMTPEQIAWLKLQQEFYEEKRRK 486 P GP G E+ PP +G G P P A + K Sbjct: 789 GPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAK 848 Query: 487 QEQVVVQQCSLQDMMVHQHGPRGVVRGPPPPYQMTPSEGWAPGGTEPFSDGI-NMPHSLP 545 EQ Q Q GP G GP P +T +G P + G + Sbjct: 849 GEQGEAGQKGDAGAPGPQ-GPSGAP-GPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVG 906 Query: 546 PRGMAPHPNMPGSQMRLPGFAGMINSEM----EGPNVPNPASRPGLSGVSWP-------- 593 P G +P PG PG +G + GP P A PGL G + P Sbjct: 907 PPGSNGNPGPPGP----PGPSGKDGPKGARGDSGP--PGRAGEPGLQGPAGPPGEKGEPG 960 Query: 594 DDVPKIPDGRNFPPG----QGIFSGPG-RGER-FPNPQGLSEEMFQQQL--AEKQLGLPP 645 DD P +G P G +GI PG RGER FP G S E +Q A G P Sbjct: 961 DDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPG 1020 Query: 646 GMAMEGIR-PSMEMNRM-IPGSQRHMEPGNNP---IFPRIPVEGPLSPSRGDFPKGIPPQ 700 + G+ P+ E R PG+ PG + + G + P G P Sbjct: 1021 PVGPPGLTGPAGEPGREGSPGADG--PPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGP 1078 Query: 701 MGP-GRELEFGMVPSGMKGDVNLNVNMGSNSQMIPQKMR----EAGAGPEEMLKLRPGGS 755 GP G++ + G +G +G + + G+ PQ R EAG E LK G + Sbjct: 1079 AGPTGKQGDRG--EAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFT 1136 Query: 756 DMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPMSQGPGSNSGLRNLREPIGPDQRTNSRLS 815 + + +P P G P + G + GP SG R P+GP + + Sbjct: 1137 GL-----QGLPGPPG--PSGDQG---------ASGPAGPSGPRGPPGPVGPSGKDGANGI 1180 Query: 816 HMPPLPLNPSSNPTSL-------NTAPPVQRGLGRKPLDISV-AGSQVHSPGINPLK 864 P P P N PP G +D+S AG G +PL+ Sbjct: 1181 PGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQ 1237 Score = 45.1 bits (105), Expect = 5e-04 Identities = 66/245 (26%), Positives = 82/245 (33%), Gaps = 62/245 (25%) Query: 1219 DLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGE---------VPGRKQPQGPGPG 1269 D+++ + P IP + I P++ + + Q P+G+ + G K P GP Sbjct: 71 DVKDCLSPE---IPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGP--- 124 Query: 1270 FSHMQGMMGEQAPRMGLALPG-MGGPGPVGTPDIPLGTA--PSMPGH-NPMRPPAF---- 1321 QG GEQ PR G G PGP G P GT P PG P PP Sbjct: 125 ----QGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP-GTPGNPGPPGPPGPPGPPGLGGNF 179 Query: 1322 ------------------LQQGMMGPHHRMMSPAQSTMPGQPTLMSNPA------AAVGM 1357 + QG MGP P + PG NP + M Sbjct: 180 AAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPM 239 Query: 1358 IPGKDRGPAGLYTHPGPVGSPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQG 1417 P GP G G G PG G GP P RG G+ G Sbjct: 240 GPRGPPGPPGKPGDDGEAGKPG----KAGERGP------PGPQGARGFPGTPGLPGVKGH 289 Query: 1418 PGNPG 1422 G PG Sbjct: 290 RGYPG 294 Score = 37.4 bits (85), Expect = 0.10 Identities = 67/273 (24%), Positives = 96/273 (35%), Gaps = 47/273 (17%) Query: 504 QHGPRGVVRGPPPPYQMTPSEGWAPGGTEPFSD-------GINMPHSLPPRGMAPHPNMP 556 Q G RG P P + P + APG + G+ P P R +P + P Sbjct: 988 QRGERGFPGLPGPSGE--PGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGP 1045 Query: 557 GSQMRLPGFAGMINSEME-----GPNVPNPASRPGLSGVSWPDDVPKIPDGRNFPPGQGI 611 + G AG+ E P P P PG +G + + G P G Sbjct: 1046 PGR---DGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG-DRGEAGAQGPMGP-- 1099 Query: 612 FSGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMI----PGSQR 667 SGP PQG + + + G P ++G R + + P + Sbjct: 1100 -SGPAGARGIQGPQGPRGD-------KGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQ 1151 Query: 668 HMEPGNNPIFPRIPVEGPLSPSRGDFPKGIPPQMGP----GRELEFGMV-------PSGM 716 P PR P GP+ PS D GIP +GP GR E G P G Sbjct: 1152 GASGPAGPSGPRGP-PGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGP 1210 Query: 717 KGDVNLNVNMGSNSQMIPQKMREAGAGPEEMLK 749 G ++M + + + P RE G P + ++ Sbjct: 1211 PGPPGPGIDMSAFAGLGP---REKGPDPLQYMR 1240 Score = 37.0 bits (84), Expect = 0.14 Identities = 70/271 (25%), Positives = 91/271 (33%), Gaps = 55/271 (20%) Query: 234 LPQQPPAPANQDQNSSQNTRLQPTPPIP----APAPKPAAPPRPLDRESPGVENKL---- 285 LP P Q + R P P P PA +P P PG + Sbjct: 997 LPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKG 1056 Query: 286 ----IPSVGSPASSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGEP 341 +VG+P + P PP GP P + + A + P P +G Sbjct: 1057 DRGETGAVGAPGA--PGPPGSPGPAG--------PTGKQGDRGEAGAQGPMGPSGPAGAR 1106 Query: 342 PTLG-ENPDGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQS----GGPQQNPGVLD 396 G + P G E E ER L+ R FTG Q GP + G Sbjct: 1107 GIQGPQGPRGDKGEAGEPGERGLKGHRG-----------FTGLQGLPGPPGPSGDQGA-S 1154 Query: 397 GPQ--KKPEGPIQAMMAQSQSLGKG-------PGPRTDVG--APFGPQGHRDVPFSPDEM 445 GP P GP + + G PGPR G P GP G+ P P Sbjct: 1155 GPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPP 1214 Query: 446 VPP-SMNSQSG----TIGPDHLDHMTPEQIA 471 P M++ +G GPD L +M +Q A Sbjct: 1215 GPGIDMSAFAGLGPREKGPDPLQYMRADQAA 1245 Score = 32.3 bits (72), Expect = 3.3 Identities = 28/95 (29%), Positives = 35/95 (36%), Gaps = 7/95 (7%) Query: 30 PPTVMSPSGNPQLDSKFSNQGKQG--GSASQSQPSPCDSKSGGHTPKALPGPGGSMGLKN 87 PP P G P L F+ Q G A +Q G P+ PGP G+ G + Sbjct: 163 PPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQG 222 Query: 88 GAGN-GAKGKGKRERSISADSFDQRDPGTPNDDSD 121 GN G G E +S + PG P D Sbjct: 223 FQGNPGEPG----EPGVSGPMGPRGPPGPPGKPGD 253 Score = 30.8 bits (68), Expect = 9.7 Identities = 40/185 (21%), Positives = 57/185 (30%), Gaps = 38/185 (20%) Query: 3 SSNPKVRSSPSGNTQSSPKSKQEVMVRPPTVMSPSGNPQLDSKFSNQGKQG-----GSAS 57 + PK S P+G PP P G + + G G G Sbjct: 727 TDGPKGASGPAG---------------PPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVG 771 Query: 58 QSQPSPCDSKSGGHT---PKALPGPGGSMGLKNGAGN-------GAKGK-GKRERS---- 102 + P K GG P PGP G+ G K G GA+G G+R + Sbjct: 772 EKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPG 831 Query: 103 ---ISADSFDQRDPGTPNDDSDIKECNSADHIKSQDSQHTPHSMTPSNATAPRSSTPSHG 159 + PG + + + A Q P P+ T P+ + + G Sbjct: 832 PAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQG 891 Query: 160 QTTAT 164 AT Sbjct: 892 PPGAT 896 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 105 bits (261), Expect = 4e-22 Identities = 302/1220 (24%), Positives = 393/1220 (32%), Gaps = 195/1220 (15%) Query: 279 PGVENKLIPSVGSPASSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPP-PVS 337 PG ++ G P P G + P +G + P P PP P Sbjct: 40 PGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPG 99 Query: 338 SGEPPTLGENPDGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSGGP-----QQNP 392 PP LG N + + Q L +Q + P +G P Q NP Sbjct: 100 PPGPPGLGGNFAAQMAGGFDEKAGGAQ-LGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNP 158 Query: 393 GV-----LDGPQ--KKPEGPIQAMMAQSQSLGKGPGPRTDVGAPFGPQGHRDVPFSPD-- 443 G + GP + P GP GK PG + G P GPQG R P +P Sbjct: 159 GEPGEPGVSGPMGPRGPPGP-PGKPGDDGEAGK-PGKAGERGPP-GPQGARGFPGTPGLP 215 Query: 444 ----------------EMVPPSMNSQSGTIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKQ 487 E P + +SG+ G ++ +P + L E + Sbjct: 216 GVKGHRGYPGLDGAKGEAGAPGVKGESGSPG----ENGSPGPMGPRGLPGE--RGRTGPA 269 Query: 488 EQVVVQQCSLQDMMVHQHGPRGVVRGPPPPY------QMTPSEGWAPGGTEPFSDGINMP 541 + Q GP G GP P + P+ P G + P Sbjct: 270 GAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTP 329 Query: 542 HSLPPRGMAPHPN---MPGSQ--MRLPGFAGMINSEMEGPNVPNPASRPGLSGVSWPDDV 596 S P G + +P +PG++ PG AG P P P PG G + P Sbjct: 330 GSPGPAGASGNPGTDGIPGAKGSAGAPGIAG-------APGFPGPRGPPGPQGATGPLG- 381 Query: 597 PKIPDGRNFPPGQGIFSGPG--RGERFP-NPQGLSEEMFQQQLAEKQLGLPPGMAMEGIR 653 P G+ PG F G +GE P PQG ++ + G P G+ G Sbjct: 382 ---PKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGAR-GEPGGVGPIG-- 435 Query: 654 PSMEMNRMIPGSQRHMEPGNNPIFPRIPVEGPLSPSRGDFPKGIPPQMGPGRELEFGMVP 713 P E R PG++ PG + + G PS PKG PGR E G+ Sbjct: 436 PPGE--RGAPGNRGF--PGQDGLAGPKGAPGERGPSGLAGPKGANGD--PGRPGEPGL-- 487 Query: 714 SGMKGDVNLNVNMGSNSQMIPQKMREAGAGPEEMLKLRPGGSDMLPAQQKMVPLPFGEHP 773 G +G + G ++ P P E + P G Q ++ P + Sbjct: 488 PGARGLTGRPGDAGPQGKVGPS------GAPGEDGRPGPPGPQGARGQPGVMGFPGPKGA 541 Query: 774 QQEYGMGPRPFLPMSQG----PGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPT 829 E G LP + G PG + G P GP R P P P Sbjct: 542 NGEPGKAGEKGLPGAPGLRGLPGKD-GETGAAGPPGPAGPAGERGEQGAPGPSGFQGLP- 599 Query: 830 SLNTAPPVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGNLKSPQTP 889 PP G G KP D V G + +PG L P + GSP + Q P Sbjct: 600 ----GPPGPPGEGGKPGDQGVPG-EAGAPG---LVGPRGERGFPGERGSPGA--QGLQGP 649 Query: 890 SQLAGM--------LAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTS-SPKPP 940 L G +GPA + PP L P + + P K P Sbjct: 650 RGLPGTPGTDGPKGASGPAGPPGAQGPPGL---QGMPGERGAAGIAGPKGDRGDVGEKGP 706 Query: 941 LQSPGIPPNHKAPLTMASPAMLG-NVESG--GPPPPTASQPASVNIPGSLPSSTPYTMPP 997 +PG + P G N E G GPP P S A P T PP Sbjct: 707 EGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGAR-----GAPGERGETGPP 761 Query: 998 EPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMG 1057 P + FA P D P A+ + Sbjct: 762 GP--------------AGFAGPPGA--------------DGQPGAKGEQGEAGQKGDAGA 793 Query: 1058 INTQNPRISGPNPVVPMPTLSPMGMTQPLSHSNQMPSPNAVGPNIPP--HGVPMGPGLMS 1115 Q P P P P P G P A G PP +G P PG Sbjct: 794 PGPQGPS-GAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG 852 Query: 1116 HNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPSGGQGSFPGGMGFPGE- 1174 + G P GR G P P P ++ +GPSG +G PG G G+ Sbjct: 853 PSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGP-PGPQGLAGQR 911 Query: 1175 GPLGRPSN--------LPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDP--DLQEVI 1224 G +G P LP S + K G PG G P T P + Sbjct: 912 GIVGLPGQRGERGFPGLPGPSGEPG--KQGAPGASGDRGPPGPVGPPGLTGPAGEPGREG 969 Query: 1225 RPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPGP-GFSHMQGMMGEQAPR 1283 PGA G P D + + + RGE P PGP G G G+Q R Sbjct: 970 SPGADGPPGRDGAAGVKGD----------RGETGAVGAPGAPGPPGSPGPAGPTGKQGDR 1019 Query: 1284 MGLALPGMGGP-GPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMSPAQSTMP 1342 G GP GP G I P P ++G+ G HR + Q +P Sbjct: 1020 GEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPG---ERGLKG--HRGFTGLQG-LP 1073 Query: 1343 GQPTLMSNPAAAVGMIPGKDRGPAGLYTHPGPVGSPGMMMSMQGMMGPQQNIMIPPQMRP 1402 G P + A+ P RGP PGPVG G G+ GP + PP P Sbjct: 1074 GPPGPSGDQGASGPAGPSGPRGP------PGPVGPSGKD-GANGIPGP----IGPPG--P 1120 Query: 1403 RGMAADVGMGGFSQGPGNPG 1422 RG + + G G PG PG Sbjct: 1121 RGRSGETGPAGPPGNPGPPG 1140 Score = 55.8 bits (133), Expect = 3e-07 Identities = 223/957 (23%), Positives = 307/957 (32%), Gaps = 154/957 (16%) Query: 9 RSSPSGNTQSSPKSKQEVMVRPPTVMSPSGNPQLDSKFSNQGKQGGSASQSQPSPCDSKS 68 R+ P+G + Q PP + P+G P +G+ G P+ Sbjct: 265 RTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAG-------PTGARGPE 317 Query: 69 GGHTPKALPGPGGSMGLKNGAGN-------GAKGKGKRERSISADSFD--------QRDP 113 G P+ PG GS G +GN GAKG A F Q Sbjct: 318 GAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGAT 377 Query: 114 GTPNDDSDIKECNSADHIKSQDSQHTPHSMTPSNATAP------RSSTPSHGQTTATEPT 167 G E A Q + P P A P R + G P Sbjct: 378 GPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPP 437 Query: 168 PAQKTPAKVVYVFSTEMANKAAEAVLKGQVETIVSFHIQNISNNKTERSTAPLNTQISAL 227 + P + +A +G + N + P ++ Sbjct: 438 GERGAPGNRGFPGQDGLAGPKGAPGERGP-SGLAGPKGANGDPGRPGEPGLPGARGLTGR 496 Query: 228 RNDPKPLPQQPPAPANQDQN-----SSQNTRLQP-TPPIPAPAPKPAAPPRPLDRESPGV 281 D P + P+ A + Q R QP P P P + ++ PG Sbjct: 497 PGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGA 556 Query: 282 EN-KLIPSVGSPASSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGE 340 + +P + PP GP + + G + P PP PP G+ Sbjct: 557 PGLRGLPGKDGETGAAG-PPGPAGPAGERGEQG----APGPSGFQGLP-GPPGPPGEGGK 610 Query: 341 PPTLGENPDGLSQEQLEHR-ERSLQTLRDIQRMLFPDEKEFTGAQS-GGPQQNPGV--LD 396 P G + + + R ER FP E+ GAQ GP+ PG D Sbjct: 611 PGDQGVPGEAGAPGLVGPRGERG-----------FPGERGSPGAQGLQGPRGLPGTPGTD 659 Query: 397 GPQ--KKPEGP--------IQAMMAQSQSLG-KGP-GPRTDVG----------------- 427 GP+ P GP +Q M + + G GP G R DVG Sbjct: 660 GPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLT 719 Query: 428 APFGPQGHRDVPFSPDEMVPPSMNSQSGTIG-PDHLDHMTPEQIAWLKLQQEFYEEKRRK 486 P GP G E+ PP +G G P P A + K Sbjct: 720 GPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAK 779 Query: 487 QEQVVVQQCSLQDMMVHQHGPRGVVRGPPPPYQMTPSEGWAPGGTEPFSDGI-NMPHSLP 545 EQ Q Q GP G GP P +T +G P + G + Sbjct: 780 GEQGEAGQKGDAGAPGPQ-GPSGAP-GPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVG 837 Query: 546 PRGMAPHPNMPGSQMRLPGFAGMINSEM----EGPNVPNPASRPGLSGVSWP-------- 593 P G +P PG PG +G + GP P A PGL G + P Sbjct: 838 PPGSNGNPGPPGP----PGPSGKDGPKGARGDSGP--PGRAGEPGLQGPAGPPGEKGEPG 891 Query: 594 DDVPKIPDGRNFPPG----QGIFSGPG-RGER-FPNPQGLSEEMFQQQL--AEKQLGLPP 645 DD P +G P G +GI PG RGER FP G S E +Q A G P Sbjct: 892 DDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPG 951 Query: 646 GMAMEGIR-PSMEMNRM-IPGSQRHMEPGNNP---IFPRIPVEGPLSPSRGDFPKGIPPQ 700 + G+ P+ E R PG+ PG + + G + P G P Sbjct: 952 PVGPPGLTGPAGEPGREGSPGADG--PPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGP 1009 Query: 701 MGP-GRELEFGMVPSGMKGDVNLNVNMGSNSQMIPQKMR----EAGAGPEEMLKLRPGGS 755 GP G++ + G +G +G + + G+ PQ R EAG E LK G + Sbjct: 1010 AGPTGKQGDRG--EAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFT 1067 Query: 756 DMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPMSQGPGSNSGLRNLREPIGPDQRTNSRLS 815 + + +P P G P + G + GP SG R P+GP + + Sbjct: 1068 GL-----QGLPGPPG--PSGDQG---------ASGPAGPSGPRGPPGPVGPSGKDGANGI 1111 Query: 816 HMPPLPLNPSSNPTSL-------NTAPPVQRGLGRKPLDISV-AGSQVHSPGINPLK 864 P P P N PP G +D+S AG G +PL+ Sbjct: 1112 PGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQ 1168 Score = 37.4 bits (85), Expect = 0.10 Identities = 67/273 (24%), Positives = 96/273 (35%), Gaps = 47/273 (17%) Query: 504 QHGPRGVVRGPPPPYQMTPSEGWAPGGTEPFSD-------GINMPHSLPPRGMAPHPNMP 556 Q G RG P P + P + APG + G+ P P R +P + P Sbjct: 919 QRGERGFPGLPGPSGE--PGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGP 976 Query: 557 GSQMRLPGFAGMINSEME-----GPNVPNPASRPGLSGVSWPDDVPKIPDGRNFPPGQGI 611 + G AG+ E P P P PG +G + + G P G Sbjct: 977 PGR---DGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG-DRGEAGAQGPMGP-- 1030 Query: 612 FSGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMI----PGSQR 667 SGP PQG + + + G P ++G R + + P + Sbjct: 1031 -SGPAGARGIQGPQGPRGD-------KGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQ 1082 Query: 668 HMEPGNNPIFPRIPVEGPLSPSRGDFPKGIPPQMGP----GRELEFGMV-------PSGM 716 P PR P GP+ PS D GIP +GP GR E G P G Sbjct: 1083 GASGPAGPSGPRGP-PGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGP 1141 Query: 717 KGDVNLNVNMGSNSQMIPQKMREAGAGPEEMLK 749 G ++M + + + P RE G P + ++ Sbjct: 1142 PGPPGPGIDMSAFAGLGP---REKGPDPLQYMR 1171 Score = 37.0 bits (84), Expect = 0.14 Identities = 70/271 (25%), Positives = 91/271 (33%), Gaps = 55/271 (20%) Query: 234 LPQQPPAPANQDQNSSQNTRLQPTPPIP----APAPKPAAPPRPLDRESPGVENKL---- 285 LP P Q + R P P P PA +P P PG + Sbjct: 928 LPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKG 987 Query: 286 ----IPSVGSPASSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGEP 341 +VG+P + P PP GP P + + A + P P +G Sbjct: 988 DRGETGAVGAPGA--PGPPGSPGPAG--------PTGKQGDRGEAGAQGPMGPSGPAGAR 1037 Query: 342 PTLG-ENPDGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQS----GGPQQNPGVLD 396 G + P G E E ER L+ R FTG Q GP + G Sbjct: 1038 GIQGPQGPRGDKGEAGEPGERGLKGHRG-----------FTGLQGLPGPPGPSGDQGA-S 1085 Query: 397 GPQ--KKPEGPIQAMMAQSQSLGKG-------PGPRTDVG--APFGPQGHRDVPFSPDEM 445 GP P GP + + G PGPR G P GP G+ P P Sbjct: 1086 GPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPP 1145 Query: 446 VPP-SMNSQSG----TIGPDHLDHMTPEQIA 471 P M++ +G GPD L +M +Q A Sbjct: 1146 GPGIDMSAFAGLGPREKGPDPLQYMRADQAA 1176 Score = 32.3 bits (72), Expect = 3.3 Identities = 28/95 (29%), Positives = 35/95 (36%), Gaps = 7/95 (7%) Query: 30 PPTVMSPSGNPQLDSKFSNQGKQG--GSASQSQPSPCDSKSGGHTPKALPGPGGSMGLKN 87 PP P G P L F+ Q G A +Q G P+ PGP G+ G + Sbjct: 94 PPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQG 153 Query: 88 GAGN-GAKGKGKRERSISADSFDQRDPGTPNDDSD 121 GN G G E +S + PG P D Sbjct: 154 FQGNPGEPG----EPGVSGPMGPRGPPGPPGKPGD 184 Score = 30.8 bits (68), Expect = 9.7 Identities = 40/185 (21%), Positives = 57/185 (30%), Gaps = 38/185 (20%) Query: 3 SSNPKVRSSPSGNTQSSPKSKQEVMVRPPTVMSPSGNPQLDSKFSNQGKQG-----GSAS 57 + PK S P+G PP P G + + G G G Sbjct: 658 TDGPKGASGPAG---------------PPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVG 702 Query: 58 QSQPSPCDSKSGGHT---PKALPGPGGSMGLKNGAGN-------GAKGK-GKRERS---- 102 + P K GG P PGP G+ G K G GA+G G+R + Sbjct: 703 EKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPG 762 Query: 103 ---ISADSFDQRDPGTPNDDSDIKECNSADHIKSQDSQHTPHSMTPSNATAPRSSTPSHG 159 + PG + + + A Q P P+ T P+ + + G Sbjct: 763 PAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQG 822 Query: 160 QTTAT 164 AT Sbjct: 823 PPGAT 827 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 105 bits (261), Expect = 4e-22 Identities = 330/1314 (25%), Positives = 411/1314 (31%), Gaps = 343/1314 (26%) Query: 235 PQQPPAPANQDQNSS-QNTRLQPTPP-IPAPAPKPAAPPRPLDRESPGVENKLIPSVGSP 292 PQ P AP Q + P PP IP P P +P SPG P Sbjct: 89 PQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGP 148 Query: 293 ASSTPL-----------------------PPDGTGPNSTPNNRAV--TPVSQG--SNSSS 325 + +P PP GP T + +P QG Sbjct: 149 QNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQ 208 Query: 326 ADPKAPPPPPVSSGEPPTLGENPDGLSQEQLEHRERSLQTLRDIQRML----FPD----- 376 A P PP PP + G G+ DG S ER L I+ FP Sbjct: 209 AGPSGPPGPPGAIGPSGPAGK--DGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHR 266 Query: 377 -------EKEFTGA-----QSGGPQQN--PGVLDGPQKKPEGPIQAMMAQSQSLGKGPGP 422 EK TGA ++G P +N PG + GP+ P + + + G Sbjct: 267 GFDGRNGEKGETGAPGLKGENGLPGENGAPGPM-GPRGAPGERGRPGLPGAAGARGNDGA 325 Query: 423 RTDVGAPF--GPQGHRDVPFSPD---EMVP---PSMNS---QSGTIGPD-HLDHMTPEQI 470 R G P GP G P SP E+ P P N Q G GP H P Sbjct: 326 RGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGP 385 Query: 471 AWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGV--------VRGPPPPYQMTP 522 + E GP G+ RGPP P Sbjct: 386 PGINGSPGGKGEM----------------------GPAGIPGAPGLMGARGPPGPAGANG 423 Query: 523 SEGWAPGGTEPFSDGIN-MPHSLPPRGMAPHPNMPGSQMRLPGFAGMINSEMEG-----P 576 + G G EP +G P RG A P +PG++ G G S E P Sbjct: 424 APGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAK----GEDGKDGSPGEPGANGLP 479 Query: 577 NVPNPASRPGLSGVSWPDDVPKIPDGRNFPPGQGIFSGPGRGERFPNPQGLSEEMFQQQL 636 PG G + P+ +P G P G+ GP P+G + E + Sbjct: 480 GAAGERGAPGFRGPAGPNGIP----GEKGPAGERGAPGPA------GPRGAAGEPGRD-- 527 Query: 637 AEKQLGLPPGMAMEGIR-----PSMEMNRMIPGSQ----RHMEPGNNPIFPRIPVEGPLS 687 G+P G M G+ P + PGSQ R PG + + V G Sbjct: 528 -----GVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPG 582 Query: 688 PSRGDF----------PKGIPPQMGPGRELEFGMVPSGMKGDVNLNVNMGSNSQMIPQKM 737 P D P G PQ PG+ E G P G G + G PQ + Sbjct: 583 PKGNDGAPGKNGERGGPGGPGPQGPPGKNGETG--PQGPPGPTGPGGDKGDTGPPGPQGL 640 Query: 738 REA-GAGPEEMLKLRPGGSDMLPAQQKMVPLPFGEH--PQQEYGMGPRPFLPMSQGPGSN 794 + G G P G + P + P P G+ P G G P +GP Sbjct: 641 QGLPGTGG-------PPGENGKPGE----PGPKGDAGAPGAPGGKGDAG-APGERGPPGL 688 Query: 795 SGLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLDISVAGSQ 854 +G LR GP + + PP P + P L P + GLG Sbjct: 689 AGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTP-GLQGMPGERGGLG------------ 735 Query: 855 VHSPGINPLKSPTMHQVQSPMLGSPSG----NLKSPQTPSQLAGMLAGPAAAASIKSPPV 910 SPG K G P G + P G + P A P Sbjct: 736 --SPGPKGDK------------GEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQ---PGD 778 Query: 911 LGSAAASPVHLKSPSLPAP--SPG--WTSSPKPPLQSPGIPPNHKAPLTMASPAMLGNVE 966 G A + P + P SPG + P P PG P + P G Sbjct: 779 KGEGGAPGL----PGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKG 834 Query: 967 SGGPP----PPTASQPASVNIPGSLPSSTPYTMPPEPTLSQNPLSIMMSRMSKFAMPSST 1022 GGPP PP S PA PG P P + P +P Sbjct: 835 EGGPPGVAGPPGGSGPAGP--PGPQGVKGERGSPGGPGAAGFP--------GARGLPGPP 884 Query: 1023 PLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMGINTQ---NPRISGPNPVVPMPTLSP 1079 S+ + PP S + P + PG NT +P +SGP P Sbjct: 885 ----------GSNGNPGPPGPSGS-PGKDGPPGPAGNTGAPGSPGVSGPKGDAGQP---- 929 Query: 1080 MGMTQPLSHSNQMPSPNAVGPNIPPHGVPMGPGLMSHNPIMG-HGSQEPPMVPQGRMGFP 1138 + SP A GP P PG + I G G PP +P P Sbjct: 930 ----------GEKGSPGAQGP-------PGAPGPLGIAGITGARGLAGPPGMPG-----P 967 Query: 1139 QGFPPVQSPPQQVPFPH-NGPSGGQGSFPGGMGFPG-EGPLGRPSNLPQSSADAALCKPG 1196 +G P Q + P NG SG +G PG G PG G G P +D + G Sbjct: 968 RGSPGPQGVKGESGKPGANGLSGERGP-PGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDG 1026 Query: 1197 GPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGE 1256 PGG D E PGA G P P P G+ Sbjct: 1027 SPGGKG----------------DRGENGSPGAPGAPGH----------PGPPGPVGPAGK 1060 Query: 1257 VPGRKQ--PQGPG--PGFSHMQGMMGEQAPRMGLALPGMGGPGPV----GTPDIPLGTAP 1308 R + P GP PG + +G G Q PR G G + G P P AP Sbjct: 1061 SGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNP--GAP 1118 Query: 1309 SMPGHNPMRPPAFLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGL 1368 PG PA QQG +G SP + P P S P PGKD G Sbjct: 1119 GSPG------PAG-QQGAIG------SPGPAG-PRGPVGPSGP-------PGKD----GT 1153 Query: 1369 YTHPGPVGSPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 HPGP+G PG PRG + G G PG PG Sbjct: 1154 SGHPGPIGPPG----------------------PRGNRGERGSEGSPGHPGQPG 1185 Score = 97.4 bits (241), Expect = 8e-20 Identities = 286/1111 (25%), Positives = 354/1111 (31%), Gaps = 195/1111 (17%) Query: 417 GKGP-GPRTDVGAPFGPQGHRDVPFSPDEMVPPSMNSQSGTIGPDHLDHMTPEQIAWLKL 475 G+GP GP+ D G P G G P P + P G+ GP + P Sbjct: 101 GQGPQGPKGDPGPP-GIPGRNGDPGIPGQPGSP------GSPGPPGICESCPTGPQNYSP 153 Query: 476 QQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPPPPYQMTPSEGWAPGGTEPFS 535 Q + Y+ K V V + GP G GPP P P PG P S Sbjct: 154 QYDSYDVK----SGVAVGG------LAGYPGPAGPP-GPPGP----PGTSGHPGS--PGS 196 Query: 536 DGINMPHSLPPRGMAPHPNMPGSQMRLPGFAGMINSEMEGPNVPNPASRPGLSGVSWPDD 595 G P P + P P + G AG + E P P PG G+ P Sbjct: 197 PGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGK-DGESGRPGRPGERGLPGPPGIKGPAG 255 Query: 596 VPKIP--------DGRNFPPGQGIFSGPG-RGER-FPNPQGLSEEMFQQQLAEKQLGLPP 645 +P P DGRN G+ PG +GE P G M + A + G P Sbjct: 256 IPGFPGMKGHRGFDGRNGEKGET--GAPGLKGENGLPGENGAPGPMGPRG-APGERGRPG 312 Query: 646 GMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIFPRIP-VEGPLSPSRGDFPKGIPPQMG-P 703 G R + + R G P FP P +G + P+ G P Q G P Sbjct: 313 LPGAAGARGN-DGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEP 371 Query: 704 GRELEFGMVPSGMKGDVNLNVNMGSNSQMIPQKMREAG-----------AGPEEMLKLRP 752 G + G G G +N + G +M P + A AG LR Sbjct: 372 GPQGHAGA--QGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRG 429 Query: 753 GGSDMLPAQQKMVPLPFGEHPQQ----------EYGMGPRPFLPMSQG-PGS--NSGLRN 799 G + K P P GE + E G P P + G PG+ G Sbjct: 430 GAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPG 489 Query: 800 LREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAP--PVQRGLGRKPLDISVAGSQVHS 857 R P GP N P + P A P + G+ P + GS Sbjct: 490 FRGPAGP----NGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSP-GG 544 Query: 858 PGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAAS 917 PG + P Q +S G P P P G++ P + +P G Sbjct: 545 PGSDGKPGPPGSQGESGRPGPPG-----PSGPRGQPGVMGFPGPKGNDGAPGKNGERGGP 599 Query: 918 PVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMASPAMLGNVESGGPPPPTASQ 977 P P G T PP P P K P L + G PP + Sbjct: 600 GG--PGPQGPPGKNGETGPQGPP--GPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGK 655 Query: 978 PAS------VNIPGSLPSSTPYTMPPE---PTLSQNPLSIMMSRMSKFAMPSSTPLYHDA 1028 P PG+ P E P L+ P + P + Sbjct: 656 PGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAP----------GLRGGAGPPGPEG 705 Query: 1029 IKTVASSDDDSPPARSPNLPSMNNMPGMGINTQNPRISGPNPVVP----MPTLS-PMGMT 1083 K A A +P L M G G+ + P+ P P +P P G T Sbjct: 706 GKGAAGPPGPPGAAGTPGLQGMPGERG-GLGSPGPKGDKGEPGGPGADGVPGKDGPRGPT 764 Query: 1084 QPLSHSNQMPSPNAVG----PNIP-------------------PHGVPMGPGLMSHNPIM 1120 P+ P G P +P P G P PG + Sbjct: 765 GPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPG--QNGEPG 822 Query: 1121 GHGSQEPPMV-----PQGRMGFPQGFPPVQSP-PQQVPFPHNGPSG-GQGSFPGGMGFPG 1173 G G + P P G G P G P P PQ V P G G FPG G PG Sbjct: 823 GKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPG 882 Query: 1174 E-GPLGRPSNLPQSSADAALCKPG--GPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGATG 1230 G G P S + PG GP GP T S PG +G Sbjct: 883 PPGSNGNPGPPGPSGS------PGKDGPPGPAGNTGAPGS---------------PGVSG 921 Query: 1231 IPEFDLSRIIPSEKPSQTLQYFPRGEVP----------GRKQPQG-PGP-GFSHMQGMMG 1278 P+ D + P EK S Q P P G P G PGP G QG+ G Sbjct: 922 -PKGDAGQ--PGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKG 978 Query: 1279 EQAPRMGLALPG-MGGPGPVGTPDIPLGTA-----PSMPGHNPMRPPAFLQQGMMGPHHR 1332 E L G G PGP G P + GTA PG + + P G G Sbjct: 979 ESGKPGANGLSGERGPPGPQGLPGLA-GTAGEPGRDGNPGSDGL-PGRDGSPGGKGDRGE 1036 Query: 1333 MMSPAQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGLYTHPGPVGSPGMMMSMQGMMGPQQ 1392 SP PG P P VG P G G GP G+PG S +G GPQ Sbjct: 1037 NGSPGAPGAPGHP----GPPGPVG--PAGKSGDRGESGPAGPAGAPGPAGS-RGAPGPQG 1089 Query: 1393 NIMIPPQMRPRGMAADVGMGGFSQGPGNPGN 1423 + RG A G GF PG PG+ Sbjct: 1090 PRGDKGETGERGAAGIKGHRGFPGNPGAPGS 1120 Score = 78.2 bits (191), Expect = 5e-14 Identities = 131/509 (25%), Positives = 171/509 (33%), Gaps = 72/509 (14%) Query: 937 PKPPLQSPGIPPNHKAPL-TMASPAMLGNVESGGPP--PPTASQPASVNIPGSLPS--ST 991 P+PP +P PPN + P P G G P P P S PG S + Sbjct: 89 PQPPT-APTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTG 147 Query: 992 PYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMN 1051 P P+ + + ++ + P+ P PP S + P Sbjct: 148 PQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPP------------GPPGPPGTSGH-PGSP 194 Query: 1052 NMPGMGINTQNPRISGPN-PVVPMPTLSPMGMTQPLSHSNQMPSPNAVG-PNIP----PH 1105 PG P +GP+ P P + P G S + P G P P P Sbjct: 195 GSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPA 254 Query: 1106 GVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPSGGQGSF 1165 G+P PG+ H G ++ G G G P P GP G +G+ Sbjct: 255 GIPGFPGMKGHRGFDGRNGEKGETGAPGLKG-ENGLPGENGAP--------GPMGPRGA- 304 Query: 1166 PGGMGFPG-EGPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVI 1224 PG G PG G G N +D +PG PG P + G+ P Sbjct: 305 PGERGRPGLPGAAGARGNDGARGSDG---QPGPPGPPGTAGFPGSPGAKGEVGP----AG 357 Query: 1225 RPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPGPGFSHMQGMMGEQAPRM 1284 PG+ G P Q + P+G G + P GP PG + G GE P Sbjct: 358 SPGSNGAP-------------GQRGEPGPQGHA-GAQGPPGP-PGINGSPGGKGEMGPAG 402 Query: 1285 GLALPGM----GGPGPVGTPDIP-LGTAPSMPGHN-----PMRPPAFLQQGMMGPHHRMM 1334 PG+ G PGP G P L PG N P + G+ G Sbjct: 403 IPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKG 462 Query: 1335 SPAQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGLYTHPGPVGSPGMMMSMQGMMGPQQNI 1394 + PG+P P AA RGPAG PG G G G GP+ Sbjct: 463 EDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGER-GAPGPAGPRGAA 521 Query: 1395 MIPPQMRPRGMAADVGMGGFSQGPGNPGN 1423 P + G+ GM G PG PG+ Sbjct: 522 GEPGR---DGVPGGPGMRGMPGSPGGPGS 547 Score = 71.2 bits (173), Expect = 6e-12 Identities = 247/1044 (23%), Positives = 307/1044 (29%), Gaps = 272/1044 (26%) Query: 229 NDPKPLPQQPPAPA----------------NQDQNSSQNTRLQPTPPIPAPAPKPAAPPR 272 +D +P P PP A + N + R +P P A A P PP Sbjct: 328 SDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPG 387 Query: 273 PLDRESPGVENKLIPSVGSPASSTPL----PPDGTGPNSTP-----------NNRAVTPV 317 SPG + ++ P+ G P + + PP G N P N P Sbjct: 388 I--NGSPGGKGEMGPA-GIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPG 444 Query: 318 SQGSNSSSADPKAP-----------PPPPVSSGEPPTLGEN----------PDGLSQEQL 356 +G + P P P P ++G P GE P+G+ E+ Sbjct: 445 PRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKG 504 Query: 357 EHRERSLQ-------TLRDIQRMLFPDEKEFTG--AQSGGP----QQNPGVLDGPQKKPE 403 ER + R P G GGP + P G +P Sbjct: 505 PAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPG 564 Query: 404 GPIQAMMAQSQSLGKGPGPRTDVGAPFGPQGHRDVPFSPDEMVPPSMNSQSGTIGPDHLD 463 P + + PGP+ + GAP G G R P P PP N ++G GP Sbjct: 565 PPGPSGPRGQPGVMGFPGPKGNDGAP-GKNGERGGPGGPGPQGPPGKNGETGPQGPP--- 620 Query: 464 HMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGV-----VRGPPPP- 517 GP G GPP P Sbjct: 621 ------------------------------------------GPTGPGGDKGDTGPPGPQ 638 Query: 518 -YQMTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPGSQMRLPGFAGMINSEMEGP 576 Q P G PG P P+G A P PG + G AG GP Sbjct: 639 GLQGLPGTGGPPGEN-------GKPGEPGPKGDAGAPGAPGGK----GDAGAPGE--RGP 685 Query: 577 NVPNPASRPGLSGVSWPDDVPKIPDGRNFPPG-QGIFSGPG----RGER----FPNPQGL 627 P A PGL G + P P+ G PPG G PG GER P P+G Sbjct: 686 --PGLAGAPGLRGGAGPPG-PEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKG- 741 Query: 628 SEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIFPRIPVEGPLS 687 G P G +G +PG P PI P P P Sbjct: 742 ------------DKGEPGGPGADG----------VPGKDGPRGP-TGPIGPPGPAGQPGD 778 Query: 688 PSRGDFPKGIP----PQMGPGRELEFGMV-PSGMKGDVNLNVNMGSNSQM-IPQKMREAG 741 G P G+P P+ PG E G P+G G N G + P + E G Sbjct: 779 KGEGGAP-GLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGG 837 Query: 742 ----AGPEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPMSQGPGSNSGL 797 AGP PGGS P G P G+ P G G Sbjct: 838 PPGVAGP-------PGGSG-----------PAG--PPGPQGVKGERGSPGGPGAAGFPGA 877 Query: 798 RNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLDISVAGSQVHS 857 R L P G S+ P P PS +P PP G + Sbjct: 878 RGLPGPPG---------SNGNPGPPGPSGSPG--KDGPPGPAG-------------NTGA 913 Query: 858 PGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAAS 917 PG + P Q GSP G P P L +AG A + PP + S Sbjct: 914 PGSPGVSGPKGDAGQPGEKGSP-GAQGPPGAPGPLG--IAGITGARGLAGPPGMPGPRGS 970 Query: 918 P----VHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMASPAMLGNVESGGPP-- 971 P V +S A P P PG+ T P GN S G P Sbjct: 971 PGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAG------TAGEPGRDGNPGSDGLPGR 1024 Query: 972 --PPTASQPASVNIPGSLPSSTPYTMPPEPTLSQNPLSIMMSR-MSKFAMPSSTPLYHDA 1028 P N P + + PP P P R S A P+ P Sbjct: 1025 DGSPGGKGDRGENGSPGAPGAPGHPGPPGPV---GPAGKSGDRGESGPAGPAGAP----- 1076 Query: 1029 IKTVASSDDDSPPARSPNLPSMNNMPGMGINTQNPRISGPNPVVPMPTLSPMGMTQPLSH 1088 + +P + P + R NP P G P Sbjct: 1077 ---GPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAP-------GSPGPAGQ 1126 Query: 1089 SNQMPSPNAVGPNIP--PHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQS 1146 + SP GP P P G P G H +G +G G P G P Sbjct: 1127 QGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSP-GHPGQPG 1185 Query: 1147 PPQQVPFPHNGPSGGQGSFPGGMG 1170 PP GP G G GG+G Sbjct: 1186 PP--------GPPGAPGPCCGGVG 1201 Score = 62.0 bits (149), Expect = 4e-09 Identities = 225/1011 (22%), Positives = 304/1011 (30%), Gaps = 226/1011 (22%) Query: 36 PSGNPQLDSKFSNQGKQGGSASQSQPSPCDSKSGGHTPKALPGPGGSMGLKNGAGNGAKG 95 P G P ++ +G+ G + P G P G G+ GL+ GAG K Sbjct: 382 PPGPPGINGSPGGKGEMGPAGIPGAPG----LMGARGPPGPAGANGAPGLRGGAGEPGKN 437 Query: 96 KGKRERSISADSFDQRDPGTPNDDSDIKECNSADHIKSQDSQHTPHSMTPSN---ATAPR 152 K E + + PG P K +D + +N A Sbjct: 438 GAKGEPGPRGERGEAGIPGVPG-------------AKGEDGKDGSPGEPGANGLPGAAGE 484 Query: 153 SSTPSHGQTTATEPTPAQKTPAKVVYVFSTEMANKAAEAVLKGQVETIVSFHIQNISNNK 212 P P +K PA A +G + + Sbjct: 485 RGAPGFRGPAGPNGIPGEKGPA--------GERGAPGPAGPRG-------------AAGE 523 Query: 213 TERSTAPLNTQISALRNDP-KPLPQQPPAPANQDQNSSQNTRLQPTPPIPA-PAPKPAAP 270 R P + + P P P P SQ +P PP P+ P +P Sbjct: 524 PGRDGVPGGPGMRGMPGSPGGPGSDGKPGPP-----GSQGESGRPGPPGPSGPRGQPGVM 578 Query: 271 PRPLDRESPGVENKLIPSVGSPASSTPLPPDG----TGPNSTPNNRAVTPVSQGSNSSSA 326 P + + G K G P P P G TGP P P G + Sbjct: 579 GFPGPKGNDGAPGK-NGERGGPGGPGPQGPPGKNGETGPQGPPG-----PTGPGGDKGDT 632 Query: 327 DPKAPP---------PPPVSSGEPPTLGENPD----------GLSQEQLEHRERSLQTLR 367 P P PP +G+P G D G + E L Sbjct: 633 GPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAP 692 Query: 368 DIQRMLFPDEKEFTGAQSGGPQQNPGVLDGPQKKPEGPIQAMMAQSQSLGKGPGPRTDVG 427 ++ P E G + GP PG P +Q M + LG PGP+ D G Sbjct: 693 GLRGGAGPPGPE-GGKGAAGPPGPPGAAGTP------GLQGMPGERGGLG-SPGPKGDKG 744 Query: 428 APFGPQGH----RDVPFSPDEMV-PPSMNSQSGTIGPDHLDHMTPEQIAWLKLQQEFYEE 482 P GP +D P P + PP Q G G + IA Sbjct: 745 EPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGL--PGIA----------- 791 Query: 483 KRRKQEQVVVQQCSLQDMMVHQHGPRGV-----VRGPPPP--YQMTPSEGWAPGGT---- 531 GPRG GPP P + P + PGG Sbjct: 792 -----------------------GPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERG 828 Query: 532 EPFSDGINMPHSL--PPRGMAPHPNMPGSQMRLPGFAGMINSEMEGPNVPNPASRPGLSG 589 P G P + PP G P PG Q + E P P A PG G Sbjct: 829 APGEKGEGGPPGVAGPPGGSGP-AGPPGPQ--------GVKGERGSPGGPGAAGFPGARG 879 Query: 590 VSWPDDVPKIPDGRNFPPGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAM 649 + P +G PPG PG+ + P P G G P + Sbjct: 880 LPGPPG----SNGNPGPPGPS--GSPGK-DGPPGPAG-------------NTGAPGSPGV 919 Query: 650 EGIRPSMEMNRMIPGSQRHMEPGNNPIFPRIPVEGPLSPSRG-DFPKGIP-PQMGPGREL 707 G P + + PG + P P ++ +RG P G+P P+ PG Sbjct: 920 SG--PKGDAGQ--PGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPG--- 972 Query: 708 EFGMVPSGMKGD---VNLNVNMGSNSQMIPQKMREAGAGPEEMLKLRPGGSDMLPAQQKM 764 P G+KG+ N G PQ + E + GSD LP + Sbjct: 973 -----PQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGS 1027 Query: 765 VPLPFGEHPQQEYGMGPRPFLPMSQGPGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNP 824 P G+ + E G P P GP P+GP ++ R P P Sbjct: 1028 ---PGGKGDRGENGSPGAPGAPGHPGPPG---------PVGPAGKSGDRGESGPAGPAG- 1074 Query: 825 SSNPTSLNTAPPVQ--RGLGRKPLDISVAGSQVHS--PGINPLKSPTMHQVQSPMLGSPS 880 + P AP Q RG + + AG + H PG NP +P P+ Sbjct: 1075 APGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPG-NP---------GAPGSPGPA 1124 Query: 881 GNLKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSL--------PAPSPG 932 G + +P AGP PP + P + P SPG Sbjct: 1125 GQQGAIGSPGP-----AGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPG 1179 Query: 933 WTSSPKPPLQSPGIPPNHKAPLTMASPAMLGNVESGGPPPPTASQPASVNI 983 P PP PG P + A+ A +G ++GG P +P I Sbjct: 1180 HPGQPGPP-GPPGAPGPCCGGVGAAAIAGIGGEKAGGFAPYYGDEPMDFKI 1229 Score = 50.1 bits (118), Expect = 2e-05 Identities = 166/723 (22%), Positives = 217/723 (30%), Gaps = 150/723 (20%) Query: 9 RSSPSGNTQSSPKSKQEVMVRPPTVMSPSGNPQLDSKFSNQGKQGGSASQSQPSPCDSKS 68 R P G S P+ + VM P P GN K +G GG Q P K+ Sbjct: 562 RPGPPG--PSGPRGQPGVMGFP----GPKGNDGAPGKNGERGGPGGPGPQGPPG----KN 611 Query: 69 GGHTPKALPGPGGSMGLKNGAG-------NGAKGKGKRERSISADSFDQRDPGTPNDDSD 121 G P+ PGP G G K G G G G ++ +PG P D+ Sbjct: 612 GETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTG----GPPGENGKPGEPG-PKGDAG 666 Query: 122 IKECNSADHIKSQDSQHTPHSM--TPSNATAPRSSTPSHGQTTATEPTPAQKTPAKVVYV 179 + P + P P G+ A P P + Sbjct: 667 APGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQG 726 Query: 180 FSTEMANKAAEAVLKGQVETIVSFHIQNISNNKTERS-TAPLNTQISALRNDPKPLPQQP 238 E + KG + R T P+ A + K P Sbjct: 727 MPGERGGLGSPGP-KGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAP 785 Query: 239 PAPANQDQNSSQNTRLQPTPPIPAPAP----KPAAPPRPLDRESPGVENKLIPSVGSPAS 294 P S R + PP PA P + P +R +PG + + G P Sbjct: 786 GLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGE-----GGPPG 840 Query: 295 STPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAP--------PPPPVSSGEPPTLGE 346 PP G+GP P + V +G S P A P PP S+G P G Sbjct: 841 VAG-PPGGSGPAGPPGPQGV----KGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPG- 894 Query: 347 NPDGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPGVLDGPQKKPEGPI 406 P G + D +G P +PGV GP+ P Sbjct: 895 -PSGSPGK---------------------DGPPGPAGNTGAP-GSPGV-SGPKGDAGQPG 930 Query: 407 QAMMAQSQSLGKG-PGPRTDVGAPFGPQGHRDVPFSPDEMVPPSMNSQSGTIGPDHLDHM 465 + KG PG + GAP GP G + + PP M G+ GP + Sbjct: 931 E----------KGSPGAQGPPGAP-GPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGE 979 Query: 466 TPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPPPPYQMTPSEG 525 + + A +G G RGPP P + G Sbjct: 980 SGKPGA---------------------------------NGLSG-ERGPPGPQGL---PG 1002 Query: 526 WAPGGTEPFSDGINMPHSLPPRGMAPHPNMPGSQMRLPGFAGMINSEMEGPNVPNPASRP 585 A EP DG LP R +P + PG G P P P Sbjct: 1003 LAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGH----PGPPGPVGPA 1058 Query: 586 GLSGVSWPDDVPKIPDGRNFPPGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPP 645 G SG G + P G GP P PQG + + + G Sbjct: 1059 GKSG----------DRGESGPAGPAGAPGPAGSRGAPGPQGPRGD-------KGETGERG 1101 Query: 646 GMAMEGIRPSMEMNRMIPGS-----QRHMEPGNNPIFPRIPVEGPLSPSRGDFPKGIPPQ 700 ++G R N PGS Q+ P PR PV GP P D G P Sbjct: 1102 AAGIKGHR-GFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPV-GPSGPPGKDGTSGHPGP 1159 Query: 701 MGP 703 +GP Sbjct: 1160 IGP 1162 >gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] Length = 1745 Score = 103 bits (258), Expect = 9e-22 Identities = 310/1281 (24%), Positives = 416/1281 (32%), Gaps = 258/1281 (20%) Query: 264 APKPAAPPRPLDRESPGVENKLIPSVGSPASSTPLPPDGT---GPNSTPNNRAVTPVSQG 320 +P P + + P E P+ P + TPL T G N+T R++ P S G Sbjct: 274 SPPPDSAENQTSTDIPKTET---PAPNLPPTPTPLVVTSTVTTGLNATILERSLDPDS-G 329 Query: 321 SNSSSADPKAPPPPPVSSGEPPTLGENPDGLSQEQLEHRERSLQTLRDIQRMLFPDEKEF 380 + + + KA G+ T+G PD + E + + F Sbjct: 330 TELGTLETKAARED--EEGDDSTMG--PDFRAAEYPSRTQFQI----------------F 369 Query: 381 TGAQSGGPQQNPGVLDGPQKKPEGPIQAMMAQSQSLGKGPGPRTDVGAPFGPQGHRDVPF 440 GA G + P V++ Q+ EGP A PGP+ VG P GP G P Sbjct: 370 PGAGEKGAKGEPAVIEKGQQF-EGPPGA-----------PGPQGVVG-PSGPPGPPGFPG 416 Query: 441 SPDEMVP---PSMNSQSGTIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSL 497 P P P + G GP M P Q A + ++ Q Q V+QQ L Sbjct: 417 DPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQA-QAQAVLQQTQL 475 Query: 498 QDMMVHQHGPRGVVRGPPPP----YQMTPSEGWAPGGTEPFSDGINMPHSLPPR-GMAPH 552 M GP G+ P P + E A G P G+ PH P R G Sbjct: 476 S--MKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGP--RGLQGPHGPPGRVGKMGR 531 Query: 553 PNMPGSQMR--------------LPGFAGMINSEMEGPNV--PNPASRPGLSGVSWPDDV 596 P G++ LPG G + +V P P G G P Sbjct: 532 PGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPG- 590 Query: 597 PKIPDGRNFPPGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRPSM 656 P G+ PG GP RG P + + A+ +G PPG + Sbjct: 591 ---PTGQAGEPGPRGLLGP-RGSPGPTGRPGVTGIDGAPGAKGNVG-PPGEPGPPGQQGN 645 Query: 657 EMNRMIPGSQR------HMEPGNNPIFPRIP-VEGPLSPSRGDFPKGIPPQMGPGRELEF 709 ++ +PG Q P NP P +P +GPL + P G GP Sbjct: 646 HGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAG- 704 Query: 710 GMVPSGMKGDVNLNVNMGSNSQMIPQKMREAGAGPEEMLKLRPGGSDMLPAQQKM-VPLP 768 P G G + G+ E G E+ G + Q K P P Sbjct: 705 ---PPGYPGPRGVKGTSGNRGLQ-----GEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGP 756 Query: 769 FGEHPQQEYGMGPRPFLPMSQGPGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNP 828 GE GP +GP +G P P +P LP P Sbjct: 757 RGED-------GP-------EGPKGQAGQAGEEGP--PGSAGEKGKLGVPGLPGYPGRPG 800 Query: 829 TSLNTAPPVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGS-----PSGNL 883 + P G P+ + PG+ + P + + G+ P G++ Sbjct: 801 PKGSIGFPGPLG----PIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDV 856 Query: 884 KSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSP-----GWTSSPK 938 P + G ++ PP P H P G+ Sbjct: 857 GQDGAPG-----IPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTG 911 Query: 939 PPLQSPGIPPNHKAPLTMASPAMLGNVESGGPPPPTASQPASVNIPG--SLPSSTPYTMP 996 PP + + P K +G + GPP P P +PG + P Sbjct: 912 PPGPAGVLGPQGKT-------GEVGPLGERGPPGPPGP-PGEQGLPGLEGREGAKGELGP 963 Query: 997 PEPTLSQNPLSIMMSRMSKFAM--PSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNMP 1054 P P + P + K P T L D + SP R P P+ Sbjct: 964 PGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPA----G 1019 Query: 1055 GMGINTQNPRISGPNPVVPMPTLSPMGMTQPLSHSNQMPSPNAVGPNIPPHGV-PMGP-- 1111 G+G+ Q+ PV P G P + + P +GP PP P G Sbjct: 1020 GIGLPGQS---GSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEG 1076 Query: 1112 -----GLMSHNPIMGH-GSQEPPMVP-----------------QGRMGFP---------- 1138 G H G G PP P QGR G P Sbjct: 1077 DKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDG 1136 Query: 1139 -QGFPPVQSPP--QQVPFPHN-----------------------GPSGGQGS--FPGGMG 1170 +GF V PP Q +P P GP+G +G+ PGG+G Sbjct: 1137 VRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVG 1196 Query: 1171 FPGE-GPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGAT 1229 PG G G + A PG PG G+S PS P PG Sbjct: 1197 QPGAVGEKGERGDAGDPGPPGA---PGIPGPKGDIGEKGDSGPSGAAGP-------PGKK 1246 Query: 1230 GIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPGPGFSHMQGMMGEQAPRMGLALP 1289 G P D ++ P G +PG P G PG S + G GE+ P Sbjct: 1247 GPPGEDGAKGSVG----------PTG-LPGDLGPPGD-PGVSGIDGSPGEKGD------P 1288 Query: 1290 G-MGGPGPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMSPAQSTMPGQ--PT 1346 G +GGPGP G P AP PG R P+ G MG R PG P Sbjct: 1289 GDVGGPGPPGASGEP--GAPGPPGK---RGPS----GHMGREGREGEKGAKGEPGPDGPP 1339 Query: 1347 LMSNPAAAVGMIPGKDRGPAGLYTHPGPVGSPGMM-----MSMQGMMGPQQNIMIPPQMR 1401 + P A G PG+ GP GL PGPVG PG++ M G +GP + Sbjct: 1340 GRTGPMGARGP-PGRV-GPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTG 1397 Query: 1402 PRGMAADVGMGGFSQGPGNPG 1422 P+G +G+ G PG G Sbjct: 1398 PKGEKGHIGLIGLIGPPGEAG 1418 Score = 68.2 bits (165), Expect = 5e-11 Identities = 125/494 (25%), Positives = 176/494 (35%), Gaps = 115/494 (23%) Query: 967 SGGPPPPTASQPASVNIPGSLPSSTPY-TMPPEPT---LSQNPLSIMMSRMSKFAMPSST 1022 + PPP +A S +IP + TP +PP PT ++ + + + + + ++ + Sbjct: 272 TSSPPPDSAENQTSTDIP---KTETPAPNLPPTPTPLVVTSTVTTGLNATILERSLDPDS 328 Query: 1023 PLYHDAIKTVASSDDDS-------PPARSPNLPSMNNM---PGMG---------INTQNP 1063 ++T A+ +D+ P R+ PS PG G + + Sbjct: 329 GTELGTLETKAAREDEEGDDSTMGPDFRAAEYPSRTQFQIFPGAGEKGAKGEPAVIEKGQ 388 Query: 1064 RISGPNPVVPMPTLSPMGMTQPLSHSNQMPSPNAVGPNIPPHGVPMGPGLMSHNPIMGHG 1123 + GP P P P G+ P P GP P G+P PG+ G Sbjct: 389 QFEGP-PGAP----GPQGVVGPSGPPGPPGFPGDPGPP-GPAGLPGIPGI--------DG 434 Query: 1124 SQEPP----MVPQGRMGFPQGFPPV-------QSPPQQVPFPHNGPSGGQG--SFPGGMG 1170 + PP M+P G PPV Q+ QQ GP G G PG +G Sbjct: 435 IRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVG 494 Query: 1171 FPGEGPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGATG 1230 PG L L P GP G + ++ RPGA G Sbjct: 495 LPGHPGLKGEEGAEGPQGPRGLQGPHGPPGR------------------VGKMGRPGADG 536 Query: 1231 IPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPGPGFSHMQGMMGEQAPRMGLALPG 1290 RG +PG P+G GF + G+ GE+ R Sbjct: 537 A----------------------RG-LPGDTGPKGDR-GFDGLPGLPGEKGQRGDFG--H 570 Query: 1291 MGGPGPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMSPAQSTMPGQPTLMSN 1350 +G PGP G P P P +G++GP SP + PG + Sbjct: 571 VGQPGPPGEDGERGAEGPPGPTGQAGEPGP---RGLLGPRG---SPGPTGRPGVTGIDGA 624 Query: 1351 PAAAVGMIPGKDRGPAGLYTHPGPVGSPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVG 1410 P A + GP G PGP G G S QG+ GPQ I P + P G G Sbjct: 625 PGAKGNV------GPPG---EPGPPGQQGNHGS-QGLPGPQGLIGTPGEKGPPGNPGIPG 674 Query: 1411 MGGFSQGP-GNPGN 1423 + G S GP G+PG+ Sbjct: 675 LPG-SDGPLGHPGH 687 Score = 58.2 bits (139), Expect = 6e-08 Identities = 240/984 (24%), Positives = 309/984 (31%), Gaps = 236/984 (23%) Query: 235 PQQPPAPANQDQNSSQNTRLQPTPPIPAPAPKPAAPPRPLDRESPGVENKLIPSVGSPAS 294 P +P P Q + SQ P P P PP +PG+ G P S Sbjct: 634 PGEPGPPGQQGNHGSQGL---PGPQGLIGTPGEKGPPG-----NPGIP-------GLPGS 678 Query: 295 STPLP-PDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGEPPTLGENPDGLSQ 353 PL P GP +QG S+ P P P V T G GL Sbjct: 679 DGPLGHPGHEGPTGEKG-------AQGPPGSAGPPGYPGPRGVKG----TSGNR--GLQG 725 Query: 354 EQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPGVLDGPQKK--PEGPI-QAMM 410 E+ E E FP K G + G Q PG GP+ + PEGP QA Sbjct: 726 EKGEKGEDG-----------FPGFKGDVGLK--GDQGKPGA-PGPRGEDGPEGPKGQAGQ 771 Query: 411 AQSQSLGKGPGPRTDVGAPFGPQGHRDVPFSPDEMVPPSMNSQSGTIGPDHLDHMTPEQI 470 A + G + +G P +P P P G +GP E+ Sbjct: 772 AGEEGPPGSAGEKGKLGVP-------GLPGYPGRPGPKGSIGFPGPLGP------IGEKG 818 Query: 471 AWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPPPPYQMTPSEGWAPG- 529 K Q E +R + Q Q GP+G V P P E PG Sbjct: 819 KSGKTGQPGLEGERGPPGSRGERG---QPGATGQPGPKGDVGQDGAPG--IPGEKGLPGL 873 Query: 530 -GTEPFSDGINMPHSLPPRGMAPHPNMPGS-----QMRLPGFAGMIN-----------SE 572 G F P G HP G Q PG AG++ E Sbjct: 874 QGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGE 933 Query: 573 MEGPNVPNPASRPGLSGVSWPDDV-----PKIPDGRNFPPGQGIFSGPGRGERFPNPQGL 627 P P P GL G+ + P P G+ P G F GP G P P GL Sbjct: 934 RGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGL 993 Query: 628 SEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIFP-RIPVEGPL 686 + PPG G S PG + + P P + EGP+ Sbjct: 994 KGDKG-----------PPGPV--GANGS-------PGERGPLGPAGGIGLPGQSGSEGPV 1033 Query: 687 SP-----SRGDF-------PKGIPPQMGP-GRELEFGMVPSGM---KGDVNLNVNMGSNS 730 P SRG+ GIP +GP G G PSG KGDV + GS Sbjct: 1034 GPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAG--PSGEEGDKGDVGAPGHKGSKG 1091 Query: 731 QMIPQKMREAGAGPEEMLKLR-------PGGSDMLPAQQKMVPLPFGEHPQQEYGMGPRP 783 + AGP +R P G+D ++ L FG+ G R Sbjct: 1092 D-------KGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGL-FGQKGDD----GVRG 1139 Query: 784 FLPMSQGPGSNSGLRNLREPIGPDQRTN---SRLSHMPPLPLNPSSNPTSLNTAPPVQRG 840 F+ + PG L+ L P G S H P P P PT P + G Sbjct: 1140 FVGVIGPPG----LQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQG-PTGSEGTPGLPGG 1194 Query: 841 LGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGNL--KSPQTPSQLAGMLAG 898 +G+ P + G + + P +P + P G++ K PS G Sbjct: 1195 VGQ-PGAVGEKGERGDAGDPGPPGAPG--------IPGPKGDIGEKGDSGPS-------G 1238 Query: 899 PAAAASIKSPPVLGSAAAS------PVHLKSPSLPAPS-----------PGWTSSPKPPL 941 A K PP A S P L P P S PG P PP Sbjct: 1239 AAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPG 1298 Query: 942 QS--PGIP--PNHKAPLTMAS-------------------PAMLGNVESGGPPPPTASQ- 977 S PG P P + P P G + + GPP + Sbjct: 1299 ASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEG 1358 Query: 978 ----PASVNIPGSLPSSTPYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVA 1033 P V PG L P M P L + L + H + + Sbjct: 1359 LRGIPGPVGEPGLL--GAPGQMGPPGPLGPSGLPGLKGDTGPKGEKG-----HIGLIGLI 1411 Query: 1034 SSDDDSPPARSPNLPSMNNMPGMGINTQNPRISGPNPVVPMPTLS---PMGMTQPLSHSN 1090 ++ LP + PG P+ P P P+ +L P G+ PL Sbjct: 1412 GPPGEAGEKGDQGLPGVQGPPG-------PK-GDPGPPGPIGSLGHPGPPGVAGPLGQKG 1463 Query: 1091 QMPSPNAVGP--NIPPHGVPMGPG 1112 SP ++GP + P G P PG Sbjct: 1464 SKGSPGSMGPRGDTGPAGPPGPPG 1487 Score = 34.7 bits (78), Expect = 0.67 Identities = 33/148 (22%), Positives = 49/148 (33%), Gaps = 16/148 (10%) Query: 12 PSGNTQSSPKSKQEVMVRPPTVMSPSGNPQLDSKFSNQGKQGGSASQSQPSPCDSKSGGH 71 P G T + + ++ P P+G P + G +G +P P + G H Sbjct: 588 PPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGP-PGQQGNH 646 Query: 72 TPKALPGPGGSMGLKNGAGNGAKGKGKRERSISADSFDQRDPGTPNDDSDIKECNSADHI 131 + LPGP G +G G KG + PG P D + Sbjct: 647 GSQGLPGPQGLIGTP-----GEKG----------PPGNPGIPGLPGSDGPLGHPGHEGPT 691 Query: 132 KSQDSQHTPHSMTPSNATAPRSSTPSHG 159 + +Q P S P PR + G Sbjct: 692 GEKGAQGPPGSAGPPGYPGPRGVKGTSG 719 >gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] Length = 744 Score = 102 bits (255), Expect = 2e-21 Identities = 124/412 (30%), Positives = 160/412 (38%), Gaps = 82/412 (19%) Query: 1040 PPARSPNLPSMNNMPG-MGINTQNPRISGPNPVVPMPTLSPMGMTQPLSHSNQMPSPNAV 1098 P P +P M PG MG+ I + PM P G P P+ Sbjct: 155 PGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGP----------PGPHG- 203 Query: 1099 GPNIPPHGVPMGPGLMSH-NPIMGHGSQEPP-----MVPQGRMGFPQ-GFPPVQSPPQQV 1151 +P G P GPGL P G + P P+G GF G P V+ PP Sbjct: 204 ---LPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMH 260 Query: 1152 PFPHNGPSGGQG-SFPGGMGFPG-EGPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLGN 1209 P GP G G PG GFPG +GPLG KPG PG P +G Sbjct: 261 GPP--GPVGLPGVGKPGVTGFPGPQGPLG---------------KPGAPGEPGPQGPIG- 302 Query: 1210 SMPSVFTDPDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGE-VPGRKQPQGPGP 1268 +P V P + + +PG GIP P K Q L P +PG +P PGP Sbjct: 303 -VPGVQGPPGIPGIGKPGQDGIPG---QPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGP 358 Query: 1269 ----GFSHMQGMMGEQAPRMGLALPGMGGP-GPVGTPDIPLGTAPSMPGHNPMRPPAFLQ 1323 G + G +G + + + PG+GGP G G P IP PM PP + Sbjct: 359 KGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIP----------GPMGPPGAI- 407 Query: 1324 QGMMGPHHR--MMSPAQSTMP-GQPTLMSNPAAAVGMIPG--KDRGPAGLYTHPGPVGSP 1378 G GP ++ P P G+P L P PG + GP G+ PGP+G Sbjct: 408 -GFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGK-----PGFLGEVGPPGMRGLPGPIGPK 461 Query: 1379 GM--------MMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 G + + G++GP+ IP +G G+GG S G PG Sbjct: 462 GEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPG 513 Score = 81.6 bits (200), Expect = 5e-15 Identities = 155/595 (26%), Positives = 201/595 (33%), Gaps = 124/595 (20%) Query: 868 MHQVQ-SPMLGSPSGNLKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSL 926 M ++Q +P +G + K + P GP + PP P L Sbjct: 90 MKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPP------------GPPGL 137 Query: 927 PAPS-PGWTSSPKPP----LQSPGIPPNHKAPLTMASPAMLGNVESGGPPPPTA-----S 976 P PG P P + PG+P P M P G + G P Sbjct: 138 PGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQG 197 Query: 977 QPASVNIPG-SLPSSTPYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASS 1035 P +PG P P P + P + P L Sbjct: 198 PPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGL----------PGPQGL----------- 236 Query: 1036 DDDSPPARSPNLPSMNNMPGMGINTQNPRISGPNPVVPMPTLSPMGMTQPLSHSNQMPSP 1095 R P MPG P + GP V +P + G+T + P Sbjct: 237 -------RGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKP 289 Query: 1096 NAVGPNIP--PHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFP-----QGFPPVQSPP 1148 A G P P GVP G+ I G G +P G+ GFP QG P + PP Sbjct: 290 GAPGEPGPQGPIGVP---GVQGPPGIPGIGKPGQDGIP-GQPGFPGGKGEQGLPGLPGPP 345 Query: 1149 Q-----QVPFPHNGPSG--GQGSFPGGMGFPGE-GPLGRPS--NLPQSSADAALCKPGGP 1198 + FP GP G G G PG +G GE GP+G P P + P GP Sbjct: 346 GLPGIGKPGFP--GPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGP 403 Query: 1199 GGPDSFT-------VLG-NSMPSVFTDPDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQ 1250 G F ++G P +P LQ G G P F L + P Sbjct: 404 PGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQ-----GFPGKPGF-LGEVGPPGMRGLPGP 457 Query: 1251 YFPRGEVPGRKQPQGPG-PGFSHMQG---MMGEQAPRMGLALPGMGGP-GPVGTPDIPLG 1305 P+GE + P PG PG +G + G+Q + +PG+GGP GP+G P IP Sbjct: 458 IGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGP 517 Query: 1306 TA-PSMPGHNPMRPPAFLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAAAVGMIPGKDRG 1364 P +PG P P + G+ G H PG+P A+G +G Sbjct: 518 KGEPGLPG--PPGFPGIGKPGVAGLHGP---------PGKP-------GALG-----PQG 554 Query: 1365 PAGLYTHPGPVGSPGMMMSM------QGMMGPQQNIMIPPQMRPRGMAADVGMGG 1413 GL PGP G PG M QG P + I P A G G Sbjct: 555 QPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNG 609 Score = 57.4 bits (137), Expect = 1e-07 Identities = 119/452 (26%), Positives = 145/452 (32%), Gaps = 101/452 (22%) Query: 533 PFSDGINMPHSLPPRGMAPHPNMPG--------SQMRLPGFAGMINSEMEG----PNVPN 580 P G PH LP G P +PG LPG G+ + + P P Sbjct: 193 PGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPG 252 Query: 581 PASRPGLSGVSWPDDVPKI--PDGRNFPPGQGIFSGPGR-GERFPNPQG-LSEEMFQ--- 633 PG+ G P +P + P FP QG PG GE P PQG + Q Sbjct: 253 VKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGE--PGPQGPIGVPGVQGPP 310 Query: 634 ---------QQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIFPRIPVEG 684 Q Q G P G +G+ P + +PG + PG V G Sbjct: 311 GIPGIGKPGQDGIPGQPGFPGGKGEQGL-PGLPGPPGLPGIGKPGFPGPKGDRGMGGVPG 369 Query: 685 PLSPSRGDFPKGIPPQMGPGRELEFGMVPS--GMKGDVNLNVNMGSNSQMIPQKMREAGA 742 L P P G P GP E +P G G + G + PQ Sbjct: 370 ALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQ------- 422 Query: 743 GPEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPMSQGPGSNSGLRNLRE 802 GP PG P+ E G+ P P G G+R L Sbjct: 423 GP-------PG-------------------PKGEPGLQGFPGKPGFLGEVGPPGMRGLPG 456 Query: 803 PIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLDISVAGSQVHSPGINP 862 PIGP + +P LP P P + G+ P D + G PGI Sbjct: 457 PIGPKGEAGQK--GVPGLPGVPGL------LGPKGEPGI---PGDQGLQG----PPGI-- 499 Query: 863 LKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGM-LAGPAAAASIKSPPVLG--SAAASPV 919 P +G PSG + P P L GP I P V G P Sbjct: 500 -----------PGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPG 548 Query: 920 HL---KSPSLPAPSPGWTSSPKPPLQSPGIPP 948 L P LP P PG P PP P PP Sbjct: 549 ALGPQGQPGLPGP-PGPPGPPGPPAVMPPTPP 579 Score = 56.2 bits (134), Expect = 2e-07 Identities = 153/633 (24%), Positives = 200/633 (31%), Gaps = 130/633 (20%) Query: 615 PGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPGNN 674 P + P Q L +++ LA+ GL G M ++ E + P + ++P Sbjct: 42 PQMPPQIPQYQPLGQQVPHMPLAKD--GLAMGKEMPHLQYGKEYPHL-PQYMKEIQPAPR 98 Query: 675 PIFPRIPVEG---PLSPSRGDF-PKGIP-PQMGPGRELEFGMVPSGMKGDVNLNVNMGSN 729 +P +G PL+ RG+ P+G P P+ PG G G+KG G Sbjct: 99 MGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVG 158 Query: 730 SQMIPQKMREAGAGPEEMLKLRPGGSDMLPAQQKMVPL-------PFGEHPQQEYGMGPR 782 +P + GA PG + + ++ P+ P G H G Sbjct: 159 KPGMPGMPGKPGAMG------MPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGG 212 Query: 783 PFLPMSQGPGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGLG 842 P LP GP + G + L P G + MP P PP G+ Sbjct: 213 PGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKG---------PP---GMH 260 Query: 843 RKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSG-NLKSPQTPSQLAGMLAGPAA 901 P + + G V PG+ P Q P LG P PQ P + G+ GP Sbjct: 261 GPPGPVGLPG--VGKPGVTGFPGP-----QGP-LGKPGAPGEPGPQGPIGVPGV-QGPPG 311 Query: 902 AASIKSP-----PVLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQSP------GIPPNH 950 I P P P LP P PG KP P G P Sbjct: 312 IPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGP-PGLPGIGKPGFPGPKGDRGMGGVPGA 370 Query: 951 KAPLTMASPAMLGNVESGGPPPPTASQPASVNIPGSLPSSTPYTMPPEPTLSQNPLSIMM 1010 P P +G GGPP +P IPG + PP P Sbjct: 371 LGPRGEKGP--IGAPGIGGPP----GEPGLPGIPGPMG-------PPGAIGFPGPKG--- 414 Query: 1011 SRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMGINTQNPRISG-PN 1069 P P P P L PG P + G P Sbjct: 415 --EGGIVGPQGPP----------------GPKGEPGLQGFPGKPGFLGEVGPPGMRGLPG 456 Query: 1070 PVVPMPTLSPMGMTQPLSHSNQMPS-PNAVGPNIPPHGVPMGPGLMSHNPIMGHGSQEPP 1128 P+ P G+ +P P +GP P G+P GL I G G Sbjct: 457 PIGPKGEAGQKGVPG-------LPGVPGLLGPKGEP-GIPGDQGLQGPPGIPGIGG---- 504 Query: 1129 MVPQGRMGFPQGFPPVQSPPQQVPFPHNGPSGGQGSFPGGMGFPG---------EGPLGR 1179 P G +G P G P GP G G PG GFPG GP G+ Sbjct: 505 --PSGPIG-PPGIP--------------GPKGEPG-LPGPPGFPGIGKPGVAGLHGPPGK 546 Query: 1180 PSNLPQSSADAALCKPGGPGGPDSFTVLGNSMP 1212 P L PG PG P V+ + P Sbjct: 547 PGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPP 579 Score = 43.5 bits (101), Expect = 0.001 Identities = 104/420 (24%), Positives = 139/420 (33%), Gaps = 75/420 (17%) Query: 233 PLPQQPPAPANQDQNSSQNTRLQPTPPIPAPAPKPAAPPRPLDRESPGVENKLIPSVGSP 292 P PQ PP P P P P P P P P + G P Sbjct: 193 PGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDK----GFGMP 248 Query: 293 -ASSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGEPPTLGENPDGL 351 A PP GP P + V + + P+ P P + GEP G P G+ Sbjct: 249 GAPGVKGPPGMHGP---PGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQG--PIGV 303 Query: 352 SQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPGVLDGPQKKPEGPIQAMMA 411 Q + + + P + F G + G Q PG L GP P Sbjct: 304 PGVQ---GPPGIPGIGKPGQDGIPGQPGFPGGK--GEQGLPG-LPGPPGLPGIGKPGFPG 357 Query: 412 QSQSLGKGP-----GPRTD---VGAPF--GPQGHRDVPFSPDEMVPPSM------NSQSG 455 G G GPR + +GAP GP G +P P M PP + G Sbjct: 358 PKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGG 417 Query: 456 TIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPP 515 +GP + + + +Q + + + GP G+ RG P Sbjct: 418 IVGP---------------------QGPPGPKGEPGLQGFPGKPGFLGEVGPPGM-RGLP 455 Query: 516 PPYQMTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPGSQ-----MRLPGFAGMIN 570 P +G A P G+ P L P+G P +PG Q +PG G + Sbjct: 456 GPIG---PKGEAGQKGVPGLPGV--PGLLGPKG---EPGIPGDQGLQGPPGIPGIGGP-S 506 Query: 571 SEMEGPNVPNPASRPGLSGVSWPDDVPKIPD----GRNFPPGQGIFSGPGRGERFPNPQG 626 + P +P P PGL G P P I G + PPG+ GP P P G Sbjct: 507 GPIGPPGIPGPKGEPGLPG---PPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPG 563 Score = 41.6 bits (96), Expect = 0.006 Identities = 103/404 (25%), Positives = 133/404 (32%), Gaps = 96/404 (23%) Query: 238 PPAPANQDQNSSQNTRLQPTPPIPAPAPKPAAPPRPLDRES---PGVENKL-IPSVGSPA 293 PP P P P P KP AP P + PGV+ IP +G P Sbjct: 262 PPGPVGLPGVGKPGVTGFPGPQ--GPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKP- 318 Query: 294 SSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSS-GEPPTLGENPDGLS 352 G + P P G P P PP + G+P G D Sbjct: 319 ----------GQDGIPGQ----PGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGD--- 361 Query: 353 QEQLEHRERSLQTLRDIQRMLFP-DEKEFTGAQS-GGPQQNPGV--LDGPQKKPEGPIQA 408 + + + L P EK GA GGP PG+ + GP P G I Sbjct: 362 -----------RGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPP-GAIGF 409 Query: 409 MMAQSQSLGKGP-GPRTDVGAPFGPQGHRDVPFSPDEMVPPSMNSQSGTIGPDHLDHMTP 467 + + GP GP G P G QG P E+ PP M G IGP Sbjct: 410 PGPKGEGGIVGPQGPPGPKGEP-GLQGFPGKPGFLGEVGPPGMRGLPGPIGP-------- 460 Query: 468 EQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGV--------VRGPPPPYQ 519 K ++ V + ++ GP+G ++GPP Sbjct: 461 ---------------KGEAGQKGVPGLPGVPGLL----GPKGEPGIPGDQGLQGPPG--- 498 Query: 520 MTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPGSQMRLPGFAGMINSEMEGPNVP 579 P G G P GI P P G+ P PG + PG AG ++ P Sbjct: 499 -IPGIGGPSGPIGP--PGIPGPKGEP--GLPGPPGFPG--IGKPGVAG-LHGPPGKPGAL 550 Query: 580 NPASRPGLSGVSWPDDVPKIPDGRNFPPGQGIFSGPGRGERFPN 623 P +PGL G P P G PP + P +GE P+ Sbjct: 551 GPQGQPGLPG-------PPGPPGPPGPPAVMPPTPPPQGEYLPD 587 Score = 36.6 bits (83), Expect = 0.18 Identities = 25/72 (34%), Positives = 28/72 (38%), Gaps = 5/72 (6%) Query: 24 QEVMVRPPTVMSPSGNPQLDSKFSNQGKQGGSASQSQPSPCDSKSGGHTPKALPGPGGSM 83 Q+ + P + P G P GK GG QP P G PK LPGP G Sbjct: 183 QKGEIGPMGIPGPQGPPGPHG-LPGIGKPGGPGLPGQPGP----KGDRGPKGLPGPQGLR 237 Query: 84 GLKNGAGNGAKG 95 G K G G G Sbjct: 238 GPKGDKGFGMPG 249 Score = 32.0 bits (71), Expect = 4.4 Identities = 27/95 (28%), Positives = 33/95 (34%), Gaps = 12/95 (12%) Query: 258 PPIPAPAPKPAAPPRPLDRESPGVENKLIPSVGSPASSTPLPPDGTGPNSTPNNRAVTPV 317 P IP P +P P P PG+ + + P P P GP P P Sbjct: 512 PGIPGPKGEPGLPGPP---GFPGIGKPGVAGLHGP----PGKPGALGPQGQPG----LPG 560 Query: 318 SQGSNSSSADPKAPPPPPVSSGE-PPTLGENPDGL 351 G P PP P GE P +G DG+ Sbjct: 561 PPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGV 595 >gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] Length = 744 Score = 102 bits (255), Expect = 2e-21 Identities = 124/412 (30%), Positives = 160/412 (38%), Gaps = 82/412 (19%) Query: 1040 PPARSPNLPSMNNMPG-MGINTQNPRISGPNPVVPMPTLSPMGMTQPLSHSNQMPSPNAV 1098 P P +P M PG MG+ I + PM P G P P+ Sbjct: 155 PGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGP----------PGPHG- 203 Query: 1099 GPNIPPHGVPMGPGLMSH-NPIMGHGSQEPP-----MVPQGRMGFPQ-GFPPVQSPPQQV 1151 +P G P GPGL P G + P P+G GF G P V+ PP Sbjct: 204 ---LPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMH 260 Query: 1152 PFPHNGPSGGQG-SFPGGMGFPG-EGPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLGN 1209 P GP G G PG GFPG +GPLG KPG PG P +G Sbjct: 261 GPP--GPVGLPGVGKPGVTGFPGPQGPLG---------------KPGAPGEPGPQGPIG- 302 Query: 1210 SMPSVFTDPDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGE-VPGRKQPQGPGP 1268 +P V P + + +PG GIP P K Q L P +PG +P PGP Sbjct: 303 -VPGVQGPPGIPGIGKPGQDGIPG---QPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGP 358 Query: 1269 ----GFSHMQGMMGEQAPRMGLALPGMGGP-GPVGTPDIPLGTAPSMPGHNPMRPPAFLQ 1323 G + G +G + + + PG+GGP G G P IP PM PP + Sbjct: 359 KGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIP----------GPMGPPGAI- 407 Query: 1324 QGMMGPHHR--MMSPAQSTMP-GQPTLMSNPAAAVGMIPG--KDRGPAGLYTHPGPVGSP 1378 G GP ++ P P G+P L P PG + GP G+ PGP+G Sbjct: 408 -GFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGK-----PGFLGEVGPPGMRGLPGPIGPK 461 Query: 1379 GM--------MMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 G + + G++GP+ IP +G G+GG S G PG Sbjct: 462 GEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPG 513 Score = 81.6 bits (200), Expect = 5e-15 Identities = 155/595 (26%), Positives = 201/595 (33%), Gaps = 124/595 (20%) Query: 868 MHQVQ-SPMLGSPSGNLKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSL 926 M ++Q +P +G + K + P GP + PP P L Sbjct: 90 MKEIQPAPRMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPP------------GPPGL 137 Query: 927 PAPS-PGWTSSPKPP----LQSPGIPPNHKAPLTMASPAMLGNVESGGPPPPTA-----S 976 P PG P P + PG+P P M P G + G P Sbjct: 138 PGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQG 197 Query: 977 QPASVNIPG-SLPSSTPYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASS 1035 P +PG P P P + P + P L Sbjct: 198 PPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGL----------PGPQGL----------- 236 Query: 1036 DDDSPPARSPNLPSMNNMPGMGINTQNPRISGPNPVVPMPTLSPMGMTQPLSHSNQMPSP 1095 R P MPG P + GP V +P + G+T + P Sbjct: 237 -------RGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKP 289 Query: 1096 NAVGPNIP--PHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFP-----QGFPPVQSPP 1148 A G P P GVP G+ I G G +P G+ GFP QG P + PP Sbjct: 290 GAPGEPGPQGPIGVP---GVQGPPGIPGIGKPGQDGIP-GQPGFPGGKGEQGLPGLPGPP 345 Query: 1149 Q-----QVPFPHNGPSG--GQGSFPGGMGFPGE-GPLGRPS--NLPQSSADAALCKPGGP 1198 + FP GP G G G PG +G GE GP+G P P + P GP Sbjct: 346 GLPGIGKPGFP--GPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGP 403 Query: 1199 GGPDSFT-------VLG-NSMPSVFTDPDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQ 1250 G F ++G P +P LQ G G P F L + P Sbjct: 404 PGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQ-----GFPGKPGF-LGEVGPPGMRGLPGP 457 Query: 1251 YFPRGEVPGRKQPQGPG-PGFSHMQG---MMGEQAPRMGLALPGMGGP-GPVGTPDIPLG 1305 P+GE + P PG PG +G + G+Q + +PG+GGP GP+G P IP Sbjct: 458 IGPKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGP 517 Query: 1306 TA-PSMPGHNPMRPPAFLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAAAVGMIPGKDRG 1364 P +PG P P + G+ G H PG+P A+G +G Sbjct: 518 KGEPGLPG--PPGFPGIGKPGVAGLHGP---------PGKP-------GALG-----PQG 554 Query: 1365 PAGLYTHPGPVGSPGMMMSM------QGMMGPQQNIMIPPQMRPRGMAADVGMGG 1413 GL PGP G PG M QG P + I P A G G Sbjct: 555 QPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGVKPPHAYGAKKGKNG 609 Score = 57.4 bits (137), Expect = 1e-07 Identities = 119/452 (26%), Positives = 145/452 (32%), Gaps = 101/452 (22%) Query: 533 PFSDGINMPHSLPPRGMAPHPNMPG--------SQMRLPGFAGMINSEMEG----PNVPN 580 P G PH LP G P +PG LPG G+ + + P P Sbjct: 193 PGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPG 252 Query: 581 PASRPGLSGVSWPDDVPKI--PDGRNFPPGQGIFSGPGR-GERFPNPQG-LSEEMFQ--- 633 PG+ G P +P + P FP QG PG GE P PQG + Q Sbjct: 253 VKGPPGMHGPPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGE--PGPQGPIGVPGVQGPP 310 Query: 634 ---------QQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIFPRIPVEG 684 Q Q G P G +G+ P + +PG + PG V G Sbjct: 311 GIPGIGKPGQDGIPGQPGFPGGKGEQGL-PGLPGPPGLPGIGKPGFPGPKGDRGMGGVPG 369 Query: 685 PLSPSRGDFPKGIPPQMGPGRELEFGMVPS--GMKGDVNLNVNMGSNSQMIPQKMREAGA 742 L P P G P GP E +P G G + G + PQ Sbjct: 370 ALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQ------- 422 Query: 743 GPEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPMSQGPGSNSGLRNLRE 802 GP PG P+ E G+ P P G G+R L Sbjct: 423 GP-------PG-------------------PKGEPGLQGFPGKPGFLGEVGPPGMRGLPG 456 Query: 803 PIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLDISVAGSQVHSPGINP 862 PIGP + +P LP P P + G+ P D + G PGI Sbjct: 457 PIGPKGEAGQK--GVPGLPGVPGL------LGPKGEPGI---PGDQGLQG----PPGI-- 499 Query: 863 LKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGM-LAGPAAAASIKSPPVLG--SAAASPV 919 P +G PSG + P P L GP I P V G P Sbjct: 500 -----------PGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPGKPG 548 Query: 920 HL---KSPSLPAPSPGWTSSPKPPLQSPGIPP 948 L P LP P PG P PP P PP Sbjct: 549 ALGPQGQPGLPGP-PGPPGPPGPPAVMPPTPP 579 Score = 56.2 bits (134), Expect = 2e-07 Identities = 153/633 (24%), Positives = 200/633 (31%), Gaps = 130/633 (20%) Query: 615 PGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPGNN 674 P + P Q L +++ LA+ GL G M ++ E + P + ++P Sbjct: 42 PQMPPQIPQYQPLGQQVPHMPLAKD--GLAMGKEMPHLQYGKEYPHL-PQYMKEIQPAPR 98 Query: 675 PIFPRIPVEG---PLSPSRGDF-PKGIP-PQMGPGRELEFGMVPSGMKGDVNLNVNMGSN 729 +P +G PL+ RG+ P+G P P+ PG G G+KG G Sbjct: 99 MGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVG 158 Query: 730 SQMIPQKMREAGAGPEEMLKLRPGGSDMLPAQQKMVPL-------PFGEHPQQEYGMGPR 782 +P + GA PG + + ++ P+ P G H G Sbjct: 159 KPGMPGMPGKPGAMG------MPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGG 212 Query: 783 PFLPMSQGPGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGLG 842 P LP GP + G + L P G + MP P PP G+ Sbjct: 213 PGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKG---------PP---GMH 260 Query: 843 RKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSG-NLKSPQTPSQLAGMLAGPAA 901 P + + G V PG+ P Q P LG P PQ P + G+ GP Sbjct: 261 GPPGPVGLPG--VGKPGVTGFPGP-----QGP-LGKPGAPGEPGPQGPIGVPGV-QGPPG 311 Query: 902 AASIKSP-----PVLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQSP------GIPPNH 950 I P P P LP P PG KP P G P Sbjct: 312 IPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGP-PGLPGIGKPGFPGPKGDRGMGGVPGA 370 Query: 951 KAPLTMASPAMLGNVESGGPPPPTASQPASVNIPGSLPSSTPYTMPPEPTLSQNPLSIMM 1010 P P +G GGPP +P IPG + PP P Sbjct: 371 LGPRGEKGP--IGAPGIGGPP----GEPGLPGIPGPMG-------PPGAIGFPGPKG--- 414 Query: 1011 SRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMGINTQNPRISG-PN 1069 P P P P L PG P + G P Sbjct: 415 --EGGIVGPQGPP----------------GPKGEPGLQGFPGKPGFLGEVGPPGMRGLPG 456 Query: 1070 PVVPMPTLSPMGMTQPLSHSNQMPS-PNAVGPNIPPHGVPMGPGLMSHNPIMGHGSQEPP 1128 P+ P G+ +P P +GP P G+P GL I G G Sbjct: 457 PIGPKGEAGQKGVPG-------LPGVPGLLGPKGEP-GIPGDQGLQGPPGIPGIGG---- 504 Query: 1129 MVPQGRMGFPQGFPPVQSPPQQVPFPHNGPSGGQGSFPGGMGFPG---------EGPLGR 1179 P G +G P G P GP G G PG GFPG GP G+ Sbjct: 505 --PSGPIG-PPGIP--------------GPKGEPG-LPGPPGFPGIGKPGVAGLHGPPGK 546 Query: 1180 PSNLPQSSADAALCKPGGPGGPDSFTVLGNSMP 1212 P L PG PG P V+ + P Sbjct: 547 PGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPP 579 Score = 43.5 bits (101), Expect = 0.001 Identities = 104/420 (24%), Positives = 139/420 (33%), Gaps = 75/420 (17%) Query: 233 PLPQQPPAPANQDQNSSQNTRLQPTPPIPAPAPKPAAPPRPLDRESPGVENKLIPSVGSP 292 P PQ PP P P P P P P P P + G P Sbjct: 193 PGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDK----GFGMP 248 Query: 293 -ASSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGEPPTLGENPDGL 351 A PP GP P + V + + P+ P P + GEP G P G+ Sbjct: 249 GAPGVKGPPGMHGP---PGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQG--PIGV 303 Query: 352 SQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPGVLDGPQKKPEGPIQAMMA 411 Q + + + P + F G + G Q PG L GP P Sbjct: 304 PGVQ---GPPGIPGIGKPGQDGIPGQPGFPGGK--GEQGLPG-LPGPPGLPGIGKPGFPG 357 Query: 412 QSQSLGKGP-----GPRTD---VGAPF--GPQGHRDVPFSPDEMVPPSM------NSQSG 455 G G GPR + +GAP GP G +P P M PP + G Sbjct: 358 PKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGG 417 Query: 456 TIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPP 515 +GP + + + +Q + + + GP G+ RG P Sbjct: 418 IVGP---------------------QGPPGPKGEPGLQGFPGKPGFLGEVGPPGM-RGLP 455 Query: 516 PPYQMTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPGSQ-----MRLPGFAGMIN 570 P +G A P G+ P L P+G P +PG Q +PG G + Sbjct: 456 GPIG---PKGEAGQKGVPGLPGV--PGLLGPKG---EPGIPGDQGLQGPPGIPGIGGP-S 506 Query: 571 SEMEGPNVPNPASRPGLSGVSWPDDVPKIPD----GRNFPPGQGIFSGPGRGERFPNPQG 626 + P +P P PGL G P P I G + PPG+ GP P P G Sbjct: 507 GPIGPPGIPGPKGEPGLPG---PPGFPGIGKPGVAGLHGPPGKPGALGPQGQPGLPGPPG 563 Score = 41.6 bits (96), Expect = 0.006 Identities = 103/404 (25%), Positives = 133/404 (32%), Gaps = 96/404 (23%) Query: 238 PPAPANQDQNSSQNTRLQPTPPIPAPAPKPAAPPRPLDRES---PGVENKL-IPSVGSPA 293 PP P P P P KP AP P + PGV+ IP +G P Sbjct: 262 PPGPVGLPGVGKPGVTGFPGPQ--GPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKP- 318 Query: 294 SSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSS-GEPPTLGENPDGLS 352 G + P P G P P PP + G+P G D Sbjct: 319 ----------GQDGIPGQ----PGFPGGKGEQGLPGLPGPPGLPGIGKPGFPGPKGD--- 361 Query: 353 QEQLEHRERSLQTLRDIQRMLFP-DEKEFTGAQS-GGPQQNPGV--LDGPQKKPEGPIQA 408 + + + L P EK GA GGP PG+ + GP P G I Sbjct: 362 -----------RGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPP-GAIGF 409 Query: 409 MMAQSQSLGKGP-GPRTDVGAPFGPQGHRDVPFSPDEMVPPSMNSQSGTIGPDHLDHMTP 467 + + GP GP G P G QG P E+ PP M G IGP Sbjct: 410 PGPKGEGGIVGPQGPPGPKGEP-GLQGFPGKPGFLGEVGPPGMRGLPGPIGP-------- 460 Query: 468 EQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGV--------VRGPPPPYQ 519 K ++ V + ++ GP+G ++GPP Sbjct: 461 ---------------KGEAGQKGVPGLPGVPGLL----GPKGEPGIPGDQGLQGPPG--- 498 Query: 520 MTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPGSQMRLPGFAGMINSEMEGPNVP 579 P G G P GI P P G+ P PG + PG AG ++ P Sbjct: 499 -IPGIGGPSGPIGP--PGIPGPKGEP--GLPGPPGFPG--IGKPGVAG-LHGPPGKPGAL 550 Query: 580 NPASRPGLSGVSWPDDVPKIPDGRNFPPGQGIFSGPGRGERFPN 623 P +PGL G P P G PP + P +GE P+ Sbjct: 551 GPQGQPGLPG-------PPGPPGPPGPPAVMPPTPPPQGEYLPD 587 Score = 36.6 bits (83), Expect = 0.18 Identities = 25/72 (34%), Positives = 28/72 (38%), Gaps = 5/72 (6%) Query: 24 QEVMVRPPTVMSPSGNPQLDSKFSNQGKQGGSASQSQPSPCDSKSGGHTPKALPGPGGSM 83 Q+ + P + P G P GK GG QP P G PK LPGP G Sbjct: 183 QKGEIGPMGIPGPQGPPGPHG-LPGIGKPGGPGLPGQPGP----KGDRGPKGLPGPQGLR 237 Query: 84 GLKNGAGNGAKG 95 G K G G G Sbjct: 238 GPKGDKGFGMPG 249 Score = 32.0 bits (71), Expect = 4.4 Identities = 27/95 (28%), Positives = 33/95 (34%), Gaps = 12/95 (12%) Query: 258 PPIPAPAPKPAAPPRPLDRESPGVENKLIPSVGSPASSTPLPPDGTGPNSTPNNRAVTPV 317 P IP P +P P P PG+ + + P P P GP P P Sbjct: 512 PGIPGPKGEPGLPGPP---GFPGIGKPGVAGLHGP----PGKPGALGPQGQPG----LPG 560 Query: 318 SQGSNSSSADPKAPPPPPVSSGE-PPTLGENPDGL 351 G P PP P GE P +G DG+ Sbjct: 561 PPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDGV 595 >gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo sapiens] Length = 1691 Score = 101 bits (252), Expect = 4e-21 Identities = 333/1366 (24%), Positives = 460/1366 (33%), Gaps = 282/1366 (20%) Query: 235 PQQPPAPANQDQNSSQNTRLQPTPPIPAPAPKPAAPPRPL-DRESPGVENKLIPSVGSPA 293 P PP P D N + + P PA PP + E G S G P Sbjct: 206 PPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPG 265 Query: 294 SSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPP-----------PPVSSGEPP 342 P +GP P T +G P P P PP G+ Sbjct: 266 PKGF--PGISGPPGFPG--LGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKG 321 Query: 343 TLGENPDGLSQEQLEHRERSLQTLRDIQRMLFPDEK-EFTGAQSGGPQQNPGVLDGPQKK 401 TLG GL+ Q ++ + + PD + GA G +PGV P K Sbjct: 322 TLGF--PGLNGFQ------GIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLK 373 Query: 402 PEGPIQAMMAQSQSLG----------------------KGPGPRTDVGAPFGPQGHRDVP 439 + IQ + S G +G RT +GA G G +P Sbjct: 374 GDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAA-GLPGRDGLP 432 Query: 440 FSPDEMVPPSMNSQSGTIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQD 499 P PPS ++ T+ H L+ +Q K + C+ D Sbjct: 433 GPPGPPGPPSPEFETETL------HNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCAC-D 485 Query: 500 MMVHQHGPRGVVRGPPPPYQMTPSEGWAPGGTEPFSDGINMPHSLP----------PRGM 549 V GP G GPP P+ + G + S G P P P+G Sbjct: 486 GGVPNTGPPGEP-GPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGK 544 Query: 550 APHP------NMPGSQ--MRLPGFAGMINSEMEG--PNVPNPASRPGLSGVSWPDD--VP 597 P MPG + GF G+I + P +P PG G +P + +P Sbjct: 545 KGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLP 604 Query: 598 KIPDGRNFPPGQGIFSGPGRG-ERFPNPQGLSEEMFQQQLAEKQLGLP--PGMAMEGIRP 654 +P + P G+ PG G P P+GL + + L +Q GLP G+ + I P Sbjct: 605 GLPGEKGHPGPPGL---PGNGLPGLPGPRGLPGDKGKDGLPGQQ-GLPGSKGITLPCIIP 660 Query: 655 SMEMNRMIPGSQRHMEPGNNPIFPRIPVEGPLSPSRGD--------------FP-----K 695 PG+ P + P P + S S+G+ FP K Sbjct: 661 GSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEK 720 Query: 696 GIPPQMG-PGRELEFGMVPSGMKGDVNLNVNMGSNSQMIPQKMREAGAGPEEMLKLRPG- 753 G+P G PG++ G+ GM G L + G+ + E GA E+ L+ G Sbjct: 721 GLPGFPGLPGKD---GL--PGMIGSPGLPGSKGATGDIFGA---ENGAPGEQGLQGLTGH 772 Query: 754 ----GSDMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPMSQGPGSNSGLRNLREPIGPDQR 809 G LP + + P P+ E G P G +SG ++ G Sbjct: 773 KGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGA 832 Query: 810 TNSRLSHMPPLPLNPSSNPTSLNTAPP---VQRGL-GRKPLDISVAGSQVHSPGINPLK- 864 P + +P T PP V++GL G K L +PG+ LK Sbjct: 833 PG-----FPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLP--------GNPGLVGLKG 879 Query: 865 SPTMHQVQS-PMLGSPSGNLKS------PQTPSQLAGMLAGPAAAASIKSPP----VLGS 913 SP V P L P G S P P L G +K P +G Sbjct: 880 SPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPG-----LPGIPGTRGLKGIPGSTGKMGP 934 Query: 914 AAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMASPAMLG----NVESGG 969 + + + P P SP+ P+ + + + + + S G E+G Sbjct: 935 SGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGR 994 Query: 970 PPPPTASQPASVNIPGSLPSSTPYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAI 1029 P PP P + +PG + + PP M + S+ + Sbjct: 995 PGPP--GLPGAPGLPGIIKGVSGKPGPPG----------FMGIRGLPGLKGSSGI--TGF 1040 Query: 1030 KTVASSDDDSPPARSPNLPSMNNMPGM-GINTQNPRISGPNPVVPMPTLSPMGMTQ---- 1084 + SP LP + +PG+ G N Q ISG P S T+ Sbjct: 1041 PGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDG 1100 Query: 1085 ---------------PLSHSNQMPSPNAVG-PNIPP-HGVPMGPGLMSHNPIMGHGSQEP 1127 + S + P A G P + G P PG H +G Sbjct: 1101 LIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPG 1160 Query: 1128 PMVPQGRMGFP-----QGFPPVQSPPQQ-------VPFPHN--GPSGGQGSFPG-GMGFP 1172 + P+G GFP G P + VP P GP G +G +PG G+G P Sbjct: 1161 LIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKG-YPGIGIGAP 1219 Query: 1173 GE-GPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGATGI 1231 G+ G G+ + PG PG S+PS+ +PG G Sbjct: 1220 GKPGLRGQKGDRGFPGLQGPAGLPGAPG---------ISLPSLIAG-------QPGDPGR 1263 Query: 1232 PEFDLSRIIPSEK-----PSQTLQYFPRGE-----VPGRKQPQGPG--PGFSHMQGMMGE 1279 P D R P P + G+ +PG K P+G PGFS + G +G Sbjct: 1264 PGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGL 1323 Query: 1280 QAPRMGLALPG-MGGPGPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMSPAQ 1338 + R PG MG PG VG P P P M G R + LQ P + A Sbjct: 1324 KGMR---GEPGFMGTPGKVGPPGDP--GFPGMKGKAGPRGSSGLQGD---PGQTPTAEAV 1375 Query: 1339 STMPGQ---------PTLMSNPAAA--VGM--------IPGKDRGPAGLYTHPGPVGSPG 1379 PG P L +P A VG+ IPGKD GP+GL PG +G PG Sbjct: 1376 QVPPGPLGLPGIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKD-GPSGLPGPPGALGDPG 1434 Query: 1380 MMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPGNMM 1425 + G+ GP P Q P GM PG PG M Sbjct: 1435 ----LPGLQGPPGFEGAPGQQGPFGM------------PGMPGQSM 1464 Score = 70.5 bits (171), Expect = 1e-11 Identities = 113/404 (27%), Positives = 144/404 (35%), Gaps = 88/404 (21%) Query: 1068 PNPVVPMPTLSPMGMTQPLSHSN---QMPSPNAVGPNIPPHGV-PMG-PGLMSHNPIMGH 1122 P P+ P G T S + P +GP P PMG PG + N I GH Sbjct: 52 PGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGH 111 Query: 1123 GSQEPPMVP---------QGRMGF--PQGFPPVQSPPQQVPFPHNGPSGGQ-----GSFP 1166 Q P P QG +GF P G+P + PP P S G GSF Sbjct: 112 PGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPP---GLPGQKGSKGDPVLAPGSFK 168 Query: 1167 GGMGFPG----------EGPLGRPSNLPQSSADAALCKPGGPG--GPDSFTVLG-NSMPS 1213 G G PG +G G P + + PG PG GPD LG Sbjct: 169 GMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKG 228 Query: 1214 VFTDPDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPG------ 1267 V D L PG G P PS + + FP+G+ + +P G Sbjct: 229 VKGDVGL-----PGPAGPP--------PSTGELEFMG-FPKGKKGSKGEPGPKGFPGISG 274 Query: 1268 -PGFSHMQGMMGEQAPRMGLALPGMGGP-GPVGTPDI--PLGT-----APSMPGHNPMRP 1318 PGF + G GE+ + +PG+ GP GP+G+ + P G PG N Sbjct: 275 PPGFPGL-GTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGF-- 331 Query: 1319 PAFLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGLYTHPGPVGSP 1378 QG+ G +PG + A + PG D G GL PG G Sbjct: 332 -----QGIEG------QKGDIGLPGPDVFIDIDGAVISGNPG-DPGVPGL---PGLKGDE 376 Query: 1379 GMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 G +QG+ GP +P G G G GNPG Sbjct: 377 G----IQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPG 416 Score = 69.7 bits (169), Expect = 2e-11 Identities = 156/632 (24%), Positives = 198/632 (31%), Gaps = 161/632 (25%) Query: 918 PVHLKSPSLPAPSPGWTSSPK-------PPLQSPGIPPNHKAPLTMASPAMLG-NVESGG 969 P+ ++ P+ P G T P L P P K P M P LG N G Sbjct: 54 PIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGP--MGVPGFLGINGIPGH 111 Query: 970 PPPPTASQP----------ASVNIPGSLPSSTPYTMPP-----------EPTLSQNPLSI 1008 P P P +V PG P P + P +P L+ Sbjct: 112 PGQPGPRGPPGLDGCNGTQGAVGFPG--PDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKG 169 Query: 1009 M-----MSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMGINTQNP 1063 M + + P P + A+ PP L NM G+G + Sbjct: 170 MKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNM-GLGFQGEKG 228 Query: 1064 ---RISGPNPVVPMPT---LSPMGMTQPLSHSNQMPSPNAV-GPNIPP------------ 1104 + P P P P+ L MG + S P P G + PP Sbjct: 229 VKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKG 288 Query: 1105 ----HGVPMGPGLMSHNPIMGHGSQEPP--MVPQGRMGFP--QGFPPVQSPPQQVPFPHN 1156 G+P PG P+ G Q PP +G +GFP GF ++ + P Sbjct: 289 EKGEKGIPGLPG--PRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLP-- 344 Query: 1157 GP-----------SGGQGSFPGGMGFPG----------EGPLGRPSNLPQSSADAALCKP 1195 GP SG G PG G PG GP G P S AL Sbjct: 345 GPDVFIDIDGAVISGNPGD-PGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQ 403 Query: 1196 GGPG------GPDSFTVLGNSMPSVFTDPDLQEVIRPGATG--IPEFDLSRIIPSEK--P 1245 G PG P T+ +P P PG G PEF+ + E P Sbjct: 404 GFPGLKGDQGNPGRTTIGAAGLPGRDGLPG-----PPGPPGPPSPEFETETLHNKESGFP 458 Query: 1246 SQTLQYFPRGE------------------VPGRKQPQGPGP----GFSHMQGMMGEQAPR 1283 + P+G VP P PGP G + G+ G + R Sbjct: 459 GLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGARGDR 518 Query: 1284 MGLALPGMGGP-GPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMS------- 1335 G GG GP G P + PS P P QGM G S Sbjct: 519 ------GSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVI 572 Query: 1336 --PAQSTMPGQPTLMSNPAAAVGMIPGKDRGPA--GLYTHPGPVGSPGMMMSMQGMMGPQ 1391 P + +PG P L P PG+ P G HPGP G PG + G+ GP Sbjct: 573 GEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGN--GLPGLPGP- 629 Query: 1392 QNIMIPPQMRPRGMAADVGMGGFSQGPGNPGN 1423 RG+ D G G G PG+ Sbjct: 630 -----------RGLPGDKGKDGLPGQQGLPGS 650 Score = 53.9 bits (128), Expect = 1e-06 Identities = 75/284 (26%), Positives = 99/284 (34%), Gaps = 67/284 (23%) Query: 1158 PSGGQGSFPGGMGFPGEGPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTD 1217 P GGQ FP +G GRP + GP GP FT + + + Sbjct: 30 PCGGQDCSGSCQCFPEKGARGRPGPIGIQ----------GPTGPQGFTG-STGLSGLKGE 78 Query: 1218 PDLQEVIRP-------GATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPGPGF 1270 ++ P G G+P F IP PG+ P+GP PG Sbjct: 79 RGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGH--------------PGQPGPRGP-PGL 123 Query: 1271 SHMQGMMGEQAPRMGLALPGMGGPGPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPH 1330 G G +G PGP G P + LG P +PG + L G Sbjct: 124 DGCNGTQG-----------AVGFPGPDGYPGL-LG-PPGLPGQKGSKGDPVLAPGSF--- 167 Query: 1331 HRMMSPAQSTMPGQPTL--MSNPAAAVGMIPGK--DRGPAGLYTHPGPVGSPG----MMM 1382 PG P L ++ P A G PG GP GL PGP G G M + Sbjct: 168 -----KGMKGDPGLPGLDGITGPQGAPG-FPGAVGPAGPPGLQGPPGPPGPLGPDGNMGL 221 Query: 1383 SMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQG----PGNPG 1422 QG G + ++ +P P ++ GF +G G PG Sbjct: 222 GFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPG 265 Score = 46.6 bits (109), Expect = 2e-04 Identities = 63/236 (26%), Positives = 83/236 (35%), Gaps = 40/236 (16%) Query: 493 QQCSLQDMMVHQHGPRGV-----VRGPPPPYQMTPSEGWAPGGTEPFSDGINMPHSLPPR 547 Q CS + G RG ++GP P T S G + E G+ P+ Sbjct: 34 QDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYG---- 89 Query: 548 GMAPHPNMPGSQMRLPGFAGMINSEMEGPNVPNPASRPGLSGVSWPDDVPKIPDGRNFPP 607 P M +PGF G IN P P P PGL G + P +P Sbjct: 90 -----PKGDKGPMGVPGFLG-INGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYP- 142 Query: 608 GQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQR 667 G+ PG P +G + L PG + +G M+ + +PG Sbjct: 143 --GLLGPPG----LPGQKGSKGDPV----------LAPG-SFKG----MKGDPGLPGLDG 181 Query: 668 HMEPGNNPIFPRIPVEGPLSPSRGDFPKGIPPQMGPGRELEFGMV-PSGMKGDVNL 722 P P FP GP P P G P +GP + G G+KGDV L Sbjct: 182 ITGPQGAPGFP--GAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGL 235 Score = 40.8 bits (94), Expect = 0.009 Identities = 71/315 (22%), Positives = 105/315 (33%), Gaps = 32/315 (10%) Query: 529 GGTEPFSDGINMPHSLP-PRGMAPHPNMPGSQMRLPGFAGMINSEMEGPNVPNPASRPGL 587 G P G+ P LP P+G +P + PG G + P + PA PG Sbjct: 1187 GTPGPSITGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQ-KGDRGFPGLQGPAGLPGA 1245 Query: 588 SGVSWPDDV---------PKI--------PDGRNFPPGQGIFSGPGRGERFPNPQGLSEE 630 G+S P + P + P G PPG G FP G Sbjct: 1246 PGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGP 1305 Query: 631 MFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIFPRIPVEGPLSPSR 690 Q + GLP + ++G+R G+ + P +P FP + +G P Sbjct: 1306 KGDQGIPGFS-GLPGELGLKGMRGEPGFM----GTPGKVGPPGDPGFPGM--KGKAGPRG 1358 Query: 691 GDFPKGIPPQMGPGRELEFGMVPSGMKGDVNLNVNMGSNSQMIPQKMREAGAGPEEMLKL 750 +G P Q ++ P G+ G + G P ++ + P K Sbjct: 1359 SSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKD 1418 Query: 751 RPGGSDMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPMSQGPGSNSGLRNLREPIGPDQRT 810 P G P LP + P G P QGP G+ +G Sbjct: 1419 GPSGLPGPPGALGDPGLPGLQGPPGFEGA------PGQQGPFGMPGMPGQSMRVGYTLVK 1472 Query: 811 NSRLSHMPPLPLNPS 825 +S+ +PP P+ S Sbjct: 1473 HSQSEQVPPCPIGMS 1487 Score = 34.3 bits (77), Expect = 0.88 Identities = 23/66 (34%), Positives = 27/66 (40%), Gaps = 3/66 (4%) Query: 31 PTVMSPSGNPQLDSKFSNQGKQGGSASQSQPSPCDSKSGGHTPKALPGPGGSMGLKNGAG 90 P ++ P G P G G + P P S +G P LPGP G G G G Sbjct: 1159 PGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGP--SITGVPGPAGLPGPKGEKGYP-GIG 1215 Query: 91 NGAKGK 96 GA GK Sbjct: 1216 IGAPGK 1221 >gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo sapiens] Length = 1690 Score = 101 bits (252), Expect = 4e-21 Identities = 333/1366 (24%), Positives = 460/1366 (33%), Gaps = 282/1366 (20%) Query: 235 PQQPPAPANQDQNSSQNTRLQPTPPIPAPAPKPAAPPRPL-DRESPGVENKLIPSVGSPA 293 P PP P D N + + P PA PP + E G S G P Sbjct: 205 PPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPG 264 Query: 294 SSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPP-----------PPVSSGEPP 342 P +GP P T +G P P P PP G+ Sbjct: 265 PKGF--PGISGPPGFPG--LGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKG 320 Query: 343 TLGENPDGLSQEQLEHRERSLQTLRDIQRMLFPDEK-EFTGAQSGGPQQNPGVLDGPQKK 401 TLG GL+ Q ++ + + PD + GA G +PGV P K Sbjct: 321 TLGF--PGLNGFQ------GIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLK 372 Query: 402 PEGPIQAMMAQSQSLG----------------------KGPGPRTDVGAPFGPQGHRDVP 439 + IQ + S G +G RT +GA G G +P Sbjct: 373 GDEGIQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAA-GLPGRDGLP 431 Query: 440 FSPDEMVPPSMNSQSGTIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQD 499 P PPS ++ T+ H L+ +Q K + C+ D Sbjct: 432 GPPGPPGPPSPEFETETL------HNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCAC-D 484 Query: 500 MMVHQHGPRGVVRGPPPPYQMTPSEGWAPGGTEPFSDGINMPHSLP----------PRGM 549 V GP G GPP P+ + G + S G P P P+G Sbjct: 485 GGVPNTGPPGEP-GPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGK 543 Query: 550 APHP------NMPGSQ--MRLPGFAGMINSEMEG--PNVPNPASRPGLSGVSWPDD--VP 597 P MPG + GF G+I + P +P PG G +P + +P Sbjct: 544 KGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLP 603 Query: 598 KIPDGRNFPPGQGIFSGPGRG-ERFPNPQGLSEEMFQQQLAEKQLGLP--PGMAMEGIRP 654 +P + P G+ PG G P P+GL + + L +Q GLP G+ + I P Sbjct: 604 GLPGEKGHPGPPGL---PGNGLPGLPGPRGLPGDKGKDGLPGQQ-GLPGSKGITLPCIIP 659 Query: 655 SMEMNRMIPGSQRHMEPGNNPIFPRIPVEGPLSPSRGD--------------FP-----K 695 PG+ P + P P + S S+G+ FP K Sbjct: 660 GSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEK 719 Query: 696 GIPPQMG-PGRELEFGMVPSGMKGDVNLNVNMGSNSQMIPQKMREAGAGPEEMLKLRPG- 753 G+P G PG++ G+ GM G L + G+ + E GA E+ L+ G Sbjct: 720 GLPGFPGLPGKD---GL--PGMIGSPGLPGSKGATGDIFGA---ENGAPGEQGLQGLTGH 771 Query: 754 ----GSDMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPMSQGPGSNSGLRNLREPIGPDQR 809 G LP + + P P+ E G P G +SG ++ G Sbjct: 772 KGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGA 831 Query: 810 TNSRLSHMPPLPLNPSSNPTSLNTAPP---VQRGL-GRKPLDISVAGSQVHSPGINPLK- 864 P + +P T PP V++GL G K L +PG+ LK Sbjct: 832 PG-----FPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLP--------GNPGLVGLKG 878 Query: 865 SPTMHQVQS-PMLGSPSGNLKS------PQTPSQLAGMLAGPAAAASIKSPP----VLGS 913 SP V P L P G S P P L G +K P +G Sbjct: 879 SPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPG-----LPGIPGTRGLKGIPGSTGKMGP 933 Query: 914 AAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMASPAMLG----NVESGG 969 + + + P P SP+ P+ + + + + + S G E+G Sbjct: 934 SGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGR 993 Query: 970 PPPPTASQPASVNIPGSLPSSTPYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAI 1029 P PP P + +PG + + PP M + S+ + Sbjct: 994 PGPP--GLPGAPGLPGIIKGVSGKPGPPG----------FMGIRGLPGLKGSSGI--TGF 1039 Query: 1030 KTVASSDDDSPPARSPNLPSMNNMPGM-GINTQNPRISGPNPVVPMPTLSPMGMTQ---- 1084 + SP LP + +PG+ G N Q ISG P S T+ Sbjct: 1040 PGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRDG 1099 Query: 1085 ---------------PLSHSNQMPSPNAVG-PNIPP-HGVPMGPGLMSHNPIMGHGSQEP 1127 + S + P A G P + G P PG H +G Sbjct: 1100 LIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPG 1159 Query: 1128 PMVPQGRMGFP-----QGFPPVQSPPQQ-------VPFPHN--GPSGGQGSFPG-GMGFP 1172 + P+G GFP G P + VP P GP G +G +PG G+G P Sbjct: 1160 LIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKG-YPGIGIGAP 1218 Query: 1173 GE-GPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGATGI 1231 G+ G G+ + PG PG S+PS+ +PG G Sbjct: 1219 GKPGLRGQKGDRGFPGLQGPAGLPGAPG---------ISLPSLIAG-------QPGDPGR 1262 Query: 1232 PEFDLSRIIPSEK-----PSQTLQYFPRGE-----VPGRKQPQGPG--PGFSHMQGMMGE 1279 P D R P P + G+ +PG K P+G PGFS + G +G Sbjct: 1263 PGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGL 1322 Query: 1280 QAPRMGLALPG-MGGPGPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMSPAQ 1338 + R PG MG PG VG P P P M G R + LQ P + A Sbjct: 1323 KGMR---GEPGFMGTPGKVGPPGDP--GFPGMKGKAGPRGSSGLQGD---PGQTPTAEAV 1374 Query: 1339 STMPGQ---------PTLMSNPAAA--VGM--------IPGKDRGPAGLYTHPGPVGSPG 1379 PG P L +P A VG+ IPGKD GP+GL PG +G PG Sbjct: 1375 QVPPGPLGLPGIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKD-GPSGLPGPPGALGDPG 1433 Query: 1380 MMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPGNMM 1425 + G+ GP P Q P GM PG PG M Sbjct: 1434 ----LPGLQGPPGFEGAPGQQGPFGM------------PGMPGQSM 1463 Score = 70.5 bits (171), Expect = 1e-11 Identities = 113/404 (27%), Positives = 144/404 (35%), Gaps = 88/404 (21%) Query: 1068 PNPVVPMPTLSPMGMTQPLSHSN---QMPSPNAVGPNIPPHGV-PMG-PGLMSHNPIMGH 1122 P P+ P G T S + P +GP P PMG PG + N I GH Sbjct: 51 PGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGH 110 Query: 1123 GSQEPPMVP---------QGRMGF--PQGFPPVQSPPQQVPFPHNGPSGGQ-----GSFP 1166 Q P P QG +GF P G+P + PP P S G GSF Sbjct: 111 PGQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPP---GLPGQKGSKGDPVLAPGSFK 167 Query: 1167 GGMGFPG----------EGPLGRPSNLPQSSADAALCKPGGPG--GPDSFTVLG-NSMPS 1213 G G PG +G G P + + PG PG GPD LG Sbjct: 168 GMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKG 227 Query: 1214 VFTDPDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPG------ 1267 V D L PG G P PS + + FP+G+ + +P G Sbjct: 228 VKGDVGL-----PGPAGPP--------PSTGELEFMG-FPKGKKGSKGEPGPKGFPGISG 273 Query: 1268 -PGFSHMQGMMGEQAPRMGLALPGMGGP-GPVGTPDI--PLGT-----APSMPGHNPMRP 1318 PGF + G GE+ + +PG+ GP GP+G+ + P G PG N Sbjct: 274 PPGFPGL-GTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGF-- 330 Query: 1319 PAFLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGLYTHPGPVGSP 1378 QG+ G +PG + A + PG D G GL PG G Sbjct: 331 -----QGIEG------QKGDIGLPGPDVFIDIDGAVISGNPG-DPGVPGL---PGLKGDE 375 Query: 1379 GMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 G +QG+ GP +P G G G GNPG Sbjct: 376 G----IQGLRGPSGVPGLPALSGVPGALGPQGFPGLKGDQGNPG 415 Score = 69.7 bits (169), Expect = 2e-11 Identities = 156/632 (24%), Positives = 198/632 (31%), Gaps = 161/632 (25%) Query: 918 PVHLKSPSLPAPSPGWTSSPK-------PPLQSPGIPPNHKAPLTMASPAMLG-NVESGG 969 P+ ++ P+ P G T P L P P K P M P LG N G Sbjct: 53 PIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGP--MGVPGFLGINGIPGH 110 Query: 970 PPPPTASQP----------ASVNIPGSLPSSTPYTMPP-----------EPTLSQNPLSI 1008 P P P +V PG P P + P +P L+ Sbjct: 111 PGQPGPRGPPGLDGCNGTQGAVGFPG--PDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKG 168 Query: 1009 M-----MSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMGINTQNP 1063 M + + P P + A+ PP L NM G+G + Sbjct: 169 MKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNM-GLGFQGEKG 227 Query: 1064 ---RISGPNPVVPMPT---LSPMGMTQPLSHSNQMPSPNAV-GPNIPP------------ 1104 + P P P P+ L MG + S P P G + PP Sbjct: 228 VKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGPPGFPGLGTTGEKG 287 Query: 1105 ----HGVPMGPGLMSHNPIMGHGSQEPP--MVPQGRMGFP--QGFPPVQSPPQQVPFPHN 1156 G+P PG P+ G Q PP +G +GFP GF ++ + P Sbjct: 288 EKGEKGIPGLPG--PRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLP-- 343 Query: 1157 GP-----------SGGQGSFPGGMGFPG----------EGPLGRPSNLPQSSADAALCKP 1195 GP SG G PG G PG GP G P S AL Sbjct: 344 GPDVFIDIDGAVISGNPGD-PGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPGALGPQ 402 Query: 1196 GGPG------GPDSFTVLGNSMPSVFTDPDLQEVIRPGATG--IPEFDLSRIIPSEK--P 1245 G PG P T+ +P P PG G PEF+ + E P Sbjct: 403 GFPGLKGDQGNPGRTTIGAAGLPGRDGLPG-----PPGPPGPPSPEFETETLHNKESGFP 457 Query: 1246 SQTLQYFPRGE------------------VPGRKQPQGPGP----GFSHMQGMMGEQAPR 1283 + P+G VP P PGP G + G+ G + R Sbjct: 458 GLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGARGDR 517 Query: 1284 MGLALPGMGGP-GPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMS------- 1335 G GG GP G P + PS P P QGM G S Sbjct: 518 ------GSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVI 571 Query: 1336 --PAQSTMPGQPTLMSNPAAAVGMIPGKDRGPA--GLYTHPGPVGSPGMMMSMQGMMGPQ 1391 P + +PG P L P PG+ P G HPGP G PG + G+ GP Sbjct: 572 GEPGKDGVPGLPGLPGLPGDGGQGFPGEKGLPGLPGEKGHPGPPGLPGN--GLPGLPGP- 628 Query: 1392 QNIMIPPQMRPRGMAADVGMGGFSQGPGNPGN 1423 RG+ D G G G PG+ Sbjct: 629 -----------RGLPGDKGKDGLPGQQGLPGS 649 Score = 53.9 bits (128), Expect = 1e-06 Identities = 75/284 (26%), Positives = 99/284 (34%), Gaps = 67/284 (23%) Query: 1158 PSGGQGSFPGGMGFPGEGPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTD 1217 P GGQ FP +G GRP + GP GP FT + + + Sbjct: 29 PCGGQDCSGSCQCFPEKGARGRPGPIGIQ----------GPTGPQGFTG-STGLSGLKGE 77 Query: 1218 PDLQEVIRP-------GATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPGPGF 1270 ++ P G G+P F IP PG+ P+GP PG Sbjct: 78 RGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGH--------------PGQPGPRGP-PGL 122 Query: 1271 SHMQGMMGEQAPRMGLALPGMGGPGPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPH 1330 G G +G PGP G P + LG P +PG + L G Sbjct: 123 DGCNGTQG-----------AVGFPGPDGYPGL-LG-PPGLPGQKGSKGDPVLAPGSF--- 166 Query: 1331 HRMMSPAQSTMPGQPTL--MSNPAAAVGMIPGK--DRGPAGLYTHPGPVGSPG----MMM 1382 PG P L ++ P A G PG GP GL PGP G G M + Sbjct: 167 -----KGMKGDPGLPGLDGITGPQGAPG-FPGAVGPAGPPGLQGPPGPPGPLGPDGNMGL 220 Query: 1383 SMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQG----PGNPG 1422 QG G + ++ +P P ++ GF +G G PG Sbjct: 221 GFQGEKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPG 264 Score = 46.6 bits (109), Expect = 2e-04 Identities = 63/236 (26%), Positives = 83/236 (35%), Gaps = 40/236 (16%) Query: 493 QQCSLQDMMVHQHGPRGV-----VRGPPPPYQMTPSEGWAPGGTEPFSDGINMPHSLPPR 547 Q CS + G RG ++GP P T S G + E G+ P+ Sbjct: 33 QDCSGSCQCFPEKGARGRPGPIGIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYG---- 88 Query: 548 GMAPHPNMPGSQMRLPGFAGMINSEMEGPNVPNPASRPGLSGVSWPDDVPKIPDGRNFPP 607 P M +PGF G IN P P P PGL G + P +P Sbjct: 89 -----PKGDKGPMGVPGFLG-INGIPGHPGQPGPRGPPGLDGCNGTQGAVGFPGPDGYP- 141 Query: 608 GQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQR 667 G+ PG P +G + L PG + +G M+ + +PG Sbjct: 142 --GLLGPPG----LPGQKGSKGDPV----------LAPG-SFKG----MKGDPGLPGLDG 180 Query: 668 HMEPGNNPIFPRIPVEGPLSPSRGDFPKGIPPQMGPGRELEFGMV-PSGMKGDVNL 722 P P FP GP P P G P +GP + G G+KGDV L Sbjct: 181 ITGPQGAPGFP--GAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGL 234 Score = 40.8 bits (94), Expect = 0.009 Identities = 71/315 (22%), Positives = 105/315 (33%), Gaps = 32/315 (10%) Query: 529 GGTEPFSDGINMPHSLP-PRGMAPHPNMPGSQMRLPGFAGMINSEMEGPNVPNPASRPGL 587 G P G+ P LP P+G +P + PG G + P + PA PG Sbjct: 1186 GTPGPSITGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRGQ-KGDRGFPGLQGPAGLPGA 1244 Query: 588 SGVSWPDDV---------PKI--------PDGRNFPPGQGIFSGPGRGERFPNPQGLSEE 630 G+S P + P + P G PPG G FP G Sbjct: 1245 PGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGP 1304 Query: 631 MFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIFPRIPVEGPLSPSR 690 Q + GLP + ++G+R G+ + P +P FP + +G P Sbjct: 1305 KGDQGIPGFS-GLPGELGLKGMRGEPGFM----GTPGKVGPPGDPGFPGM--KGKAGPRG 1357 Query: 691 GDFPKGIPPQMGPGRELEFGMVPSGMKGDVNLNVNMGSNSQMIPQKMREAGAGPEEMLKL 750 +G P Q ++ P G+ G + G P ++ + P K Sbjct: 1358 SSGLQGDPGQTPTAEAVQVPPGPLGLPGIDGIPGLTGDPGAQGPVGLQGSKGLPGIPGKD 1417 Query: 751 RPGGSDMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPMSQGPGSNSGLRNLREPIGPDQRT 810 P G P LP + P G P QGP G+ +G Sbjct: 1418 GPSGLPGPPGALGDPGLPGLQGPPGFEGA------PGQQGPFGMPGMPGQSMRVGYTLVK 1471 Query: 811 NSRLSHMPPLPLNPS 825 +S+ +PP P+ S Sbjct: 1472 HSQSEQVPPCPIGMS 1486 Score = 34.3 bits (77), Expect = 0.88 Identities = 23/66 (34%), Positives = 27/66 (40%), Gaps = 3/66 (4%) Query: 31 PTVMSPSGNPQLDSKFSNQGKQGGSASQSQPSPCDSKSGGHTPKALPGPGGSMGLKNGAG 90 P ++ P G P G G + P P S +G P LPGP G G G G Sbjct: 1158 PGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGP--SITGVPGPAGLPGPKGEKGYP-GIG 1214 Query: 91 NGAKGK 96 GA GK Sbjct: 1215 IGAPGK 1220 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 101 bits (251), Expect = 6e-21 Identities = 311/1226 (25%), Positives = 377/1226 (30%), Gaps = 265/1226 (21%) Query: 267 PAAPPRPLDRESPGVENKLIPSVGSPASSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSA 326 P P D+E+ GVE P TGP P A P G Sbjct: 96 PDGSESPTDQETTGVEG---------------PKGDTGPRG-PRGPAGPPGRDGIPGQPG 139 Query: 327 DPKAPPPPPVSSGEPPTLGENPDGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSG 386 P PP PP G PP LG N QL + DEK G Sbjct: 140 LP-GPPGPPGPPG-PPGLGGN----FAPQLSYGY---------------DEKSTGGISVP 178 Query: 387 GPQ--QNPGVLDGPQKKPEGPIQAMMAQSQSLGK----GP-GPRTDVGAPF--GPQGHRD 437 GP P L GP P GP Q G+ GP GPR G P G G Sbjct: 179 GPMGPSGPRGLPGPPGAP-GP-QGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAG 236 Query: 438 VPFSPDEMVPPSMNSQSGTIGPDHLDHMTPEQ-IAWLKLQQEFYEEKRRKQEQVVVQQCS 496 P P E PP G G L M + + L + K E + Sbjct: 237 KPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENG 296 Query: 497 LQDMMVHQHGPRGVVRGPPPPYQMTPSEGWAPGGTEPF----SDGINMPHSLP-PRGMAP 551 M GPRG+ P E PG P +DG P P G A Sbjct: 297 APGQM----GPRGL-----------PGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAG 341 Query: 552 HPNMPGSQMRLPGFAGMINSE-MEGPN-------VPNPASRPGLSGVSWPDDVPKIPDGR 603 P PG+ + G AG EGP P PA G +G D P Sbjct: 342 PPGFPGA-VGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGAN 400 Query: 604 NFPPGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMIP 663 P GI PG FP +G S + G PPG P ++ Sbjct: 401 GAP---GIAGAPG----FPGARGPS--------GPQGPGGPPGPKGNSGEPGAPGSKGDT 445 Query: 664 GSQRHMEPGNNPIFPRIPVEGPLSPSRGDFPKGIPPQMGPGRELEFGMV-PSGMKGDVNL 722 G++ EPG + V+GP P+ + +G + GP G+ P G +G Sbjct: 446 GAKG--EPGP------VGVQGPPGPAGEEGKRGARGEPGPT-----GLPGPPGERG---- 488 Query: 723 NVNMGSNSQMIPQKMREAGAGPEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQQEYGMGPR 782 G S+ P + AGP+ PA ++ P P G P+ G R Sbjct: 489 ----GPGSRGFPGA--DGVAGPKG------------PAGERGSPGPAG--PKGSPGEAGR 528 Query: 783 PFLPMSQGPGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGLG 842 P G GL GPD +T PP P P PP RG Sbjct: 529 PG---EAGLPGAKGLTGSPGSPGPDGKTG------PPGPAGQDGRPGP--PGPPGARG-- 575 Query: 843 RKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGSP--SGNLKSPQTPSQLAGMLAGPA 900 G+ P G P +G P P + AG Sbjct: 576 --------------QAGVMGFPGP------KGAAGEPGKAGERGVPGPPGAVGP--AGKD 613 Query: 901 AAASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTSSPKP--PLQSPGIPPNHKAPLTMAS 958 A + PP A P + PA SPG+ P P P G P P + + Sbjct: 614 GEAGAQGPP----GPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGA 669 Query: 959 PAMLGNVESGGPP-------PPTASQPASVN-IPGSLPSSTPYTMPPEPTLSQNP-LSIM 1009 P G G P PP + P N PG+ + P P P L M Sbjct: 670 PGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGM 729 Query: 1010 MSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMGINTQNPRISGPN 1069 +P DA A R P PG + SGP+ Sbjct: 730 PGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPI--GPPGPAGAPGDKGESGPS 787 Query: 1070 PVVPMPTLSPMGMTQPLSHSNQMPSPNAVGPN--IPPHGVPMGPGLMSHNPIMGHGSQEP 1127 P G T P GP P G PG G Sbjct: 788 --------GPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAG 839 Query: 1128 PMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPSGGQGSF--PGGMGFPGEGPLGRPSNLPQ 1185 P P G G P V +P G G +GS PG GFPG P P Sbjct: 840 PPGPAGPAGPPGPIGNVGAP---------GAKGARGSAGPPGATGFPGAAGRVGP---PG 887 Query: 1186 SSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGATGIPEFDLSRIIPSEKP 1245 S +A P GP G + G P T P RPG G P P Sbjct: 888 PSGNAGPPGPPGPAGKE-----GGKGPRGETGP----AGRPGEVG----------PPGPP 928 Query: 1246 SQTLQYFPRGEV--PGRKQPQG----PGP-GFSHMQGMMGEQAPRMGLALPGMGGPGPVG 1298 P GE PG P G PGP G + +G++G R PG+ PGP G Sbjct: 929 G------PAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGL--PGPSG 980 Query: 1299 TPDI--PLGTAPSMPGHNPMRPPAFL----QQGMMGPHHRMMSPAQSTMPGQP-----TL 1347 P P G + PM PP + G G SP + PG T Sbjct: 981 EPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETG 1040 Query: 1348 MSNPAAAVGM--IPGK--------DRGPAGLYTHPGPVGSPGMMMSMQGMMGPQQNIMIP 1397 + P A G PG DRG G GPVG G G GP+ + Sbjct: 1041 PAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGAR-GPAGPQGPRGDKGET 1099 Query: 1398 PQMRPRGMAADVGMGGFSQGPGNPGN 1423 + RG+ G G PG PG+ Sbjct: 1100 GEQGDRGIKGHRGFSGLQGPPGPPGS 1125 Score = 95.5 bits (236), Expect = 3e-19 Identities = 301/1247 (24%), Positives = 395/1247 (31%), Gaps = 238/1247 (19%) Query: 213 TERSTAPLNTQISALRNDPKPL-PQQPPAPANQDQNSSQNTRLQPTPPIPAPAPKPAAPP 271 +E T T + + D P P+ P P +D Q P +P P P P PP Sbjct: 99 SESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQ-------PGLPGP-PGPPGPP 150 Query: 272 RP-------LDRESPGVENKLIPSVGSPASSTPLPPDGT-GPNSTPNNRAVT--PVSQGS 321 P + S G + K + P P P G GP P + P G Sbjct: 151 GPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGE 210 Query: 322 NSSSAD--PKAPPPPPVSSGEPPTLGE-NPDGLSQEQLEHRERSLQTLRDIQRMLFPDEK 378 +S P+ PP PP +G+ G+ G R L + M + Sbjct: 211 PGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGM--KGHR 268 Query: 379 EFTGAQSGGPQQNPGVLDGPQKKPEGPIQAMMAQSQSLGKGPGPRTDVGAPFGPQGHRDV 438 F+G P GP+ +P P + PG R GAP GP G R Sbjct: 269 GFSGLDGAKGDAGPA---GPKGEPGSPGENGAPGQMGPRGLPGERGRPGAP-GPAGARGN 324 Query: 439 PFSPDEMVPPSMNSQSGTIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQ 498 + PP +G GP P + + E + R E Sbjct: 325 DGATGAAGPPG---PTGPAGP-------PGFPGAVGAKGEAGPQGPRGSE---------- 364 Query: 499 DMMVHQHGPRGVVRGPPPPYQMTPSEGWAPGGT-----EPFSDGINMPHSLP-------- 545 GP+GV P PP P+ P G +P + G N + Sbjct: 365 -------GPQGVRGEPGPP---GPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGA 414 Query: 546 --------------PRGMAPHPNMPGSQ--MRLPGFAGMINSEMEGPNVPNPASR----- 584 P+G + P PGS+ G G + ++GP P PA Sbjct: 415 RGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVG--VQGP--PGPAGEEGKRG 470 Query: 585 ----PGLSGVSWPDDVPKIPDGRNFPPGQGIFSGPG-RGER-FPNPQGLSEEMFQQQLAE 638 PG +G+ P P R FP G+ G GER P P G Sbjct: 471 ARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAG------------ 518 Query: 639 KQLGLPPGMAMEGIRPSMEMNRMIPGSQRHM-EPGNNPIFPRIPVEGPLSPSRGDFPKGI 697 P G E RP +PG++ PG+ + GP P G Sbjct: 519 -----PKGSPGEAGRPG---EAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGP 570 Query: 698 PPQMGPGRELEFGMVPSGMKGDVNLNVNMGSNSQMIPQKMREAGAGPEEMLKLRPGGSDM 757 P G + F P G G+ P K E G P + P G D Sbjct: 571 PGARGQAGVMGFPG-PKGAAGE--------------PGKAGERGV-PGPPGAVGPAGKDG 614 Query: 758 LPAQQKMVPLPFGEHPQQEYGMGPRPFLPMSQGPGSNSGLRNLREPIGPDQRTNSRLSHM 817 Q P P G P E G QGP + G + L P GP Sbjct: 615 EAGAQGP-PGPAG--PAGERG---------EQGPAGSPGFQGLPGPAGPPGEAGKPGEQG 662 Query: 818 PPLPLN-PSSNPTSLNTAPPVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPML 876 P L P + P +RG+ P G+ +PG + K Sbjct: 663 VPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGAN-GAPGNDGAKGDAGAPGAPGSQ 721 Query: 877 GSPSGNLKSPQTPSQLAGML--------AGPAAAASIKSPPVLG-SAAASPVHLKSPSLP 927 G+P L+ AG+ AGP A SP G P+ P P Sbjct: 722 GAPG--LQGMPGERGAAGLPGPKGDRGDAGPKGADG--SPGKDGVRGLTGPI---GPPGP 774 Query: 928 APSPG-----WTSSPKPPLQSPGIPPNHKAPLTMASPAMLGNVESGGPPPPTASQPASVN 982 A +PG S P P + G P + P G PP QP + Sbjct: 775 AGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAG-------PPGADGQPGAKG 827 Query: 983 IPGSLPSSTPYTMPPE--PTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSP 1040 PG + P P P+ + + +K A S+ P A ++ P Sbjct: 828 EPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGP--PGATGFPGAAGRVGP 885 Query: 1041 PARSPNL-PSMNNMPGMGINTQNPRISGPNPVVPMPTLSPMGMTQPLSHSNQMPSPNAVG 1099 P S N P P + PR P +G P + + SP A G Sbjct: 886 PGPSGNAGPPGPPGPAGKEGGKGPR----GETGPAGRPGEVGPPGPPGPAGEKGSPGADG 941 Query: 1100 PNIPPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFP-PVQSPPQQVPFPHNGP 1158 P P G P G+ ++G Q +G GFP G P P P +Q P +G Sbjct: 942 PAGAP-GTPGPQGIAGQRGVVGLPGQ------RGERGFP-GLPGPSGEPGKQGP---SGA 990 Query: 1159 SGGQGSFPGGMGFPGEGPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDP 1218 SG +G PG MG PG G P + A A PG G P + G + P+ P Sbjct: 991 SGERGP-PGPMGPPGLA--GPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPA--GPP 1045 Query: 1219 DLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVP-----GRKQPQGPGPGFSHM 1273 PGA G P + P+ K + P G G + P GP G Sbjct: 1046 GA-----PGAPGAP----GPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGP-QGPRGD 1095 Query: 1274 QGMMGEQAPRMGLALPGMGG-PGPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHR 1332 +G GEQ R G G GP G P P PS G GP Sbjct: 1096 KGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPS---------------GASGPAGP 1140 Query: 1333 MMSPAQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGLYTHPGPVGSPG 1379 P + PG+ L P P G AG PGP G PG Sbjct: 1141 RGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPG 1187 Score = 72.0 bits (175), Expect = 4e-12 Identities = 284/1264 (22%), Positives = 382/1264 (30%), Gaps = 261/1264 (20%) Query: 4 SNPKVRSSPSGNTQSSPKSKQEVMVRPPTVMSPSGNPQLDSKFSNQGKQGGSASQSQPSP 63 + P+ P+G Q + PP P G P L F+ Q G + Sbjct: 117 TGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGIS 176 Query: 64 CDSKSGGHTPKALPGPGGSMGLKNGAG-NGAKGKGKRERSISADSFDQRDPGTPNDDSDI 122 G P+ LPGP G+ G + G G G E S + PG P + D Sbjct: 177 VPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPG----EPGASGPMGPRGPPGPPGKNGDD 232 Query: 123 KECNSADHIKSQDSQHTPHSMTPSNATAPRSSTPSHGQTTATEPTPAQKTPAKVVYVFST 182 E + P TA H + + PA Sbjct: 233 GEAGKPGR-PGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAG-----PK 286 Query: 183 EMANKAAEAVLKGQVETIVSFHIQNISNNKTERSTAPLNTQISALRNDPKPLPQQPPAPA 242 E GQ+ ER A ND PP P Sbjct: 287 GEPGSPGENGAPGQM---------GPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPT 337 Query: 243 NQDQNSSQNTRLQPTPPIPAPAPKPAAPPRPLDRESP-GVENKLIP--------SVGSPA 293 P P A A P P E P GV + P G+P Sbjct: 338 GPAG--------PPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPG 389 Query: 294 SSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSA--DPKAPPPPPVSSGEPPTLGENPDGL 351 + P G N P A P G+ S P PP P +SGEP G D Sbjct: 390 ADG--QPGAKGANGAP-GIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTG 446 Query: 352 SQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPGVLDGPQKKPEGPIQAMMA 411 ++ + +Q P +E G + + P L GP + GP Sbjct: 447 AKGE--------PGPVGVQGPPGPAGEE--GKRGARGEPGPTGLPGPPGERGGPGSRGFP 496 Query: 412 QSQSLGKGPGPRTDVGA--PFGPQGHRDVPFSPDEMVPPSMNSQSGTIGPDHLDHMTPEQ 469 + + GP + G+ P GP+G P E P +G+ G D T Sbjct: 497 GADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPP 556 Query: 470 IAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPPPPYQMTPSEGWAPG 529 GP G P PP P Sbjct: 557 ------------------------------------GPAGQDGRPGPP---------GPP 571 Query: 530 GTEPFSDGINMPHSLPPRGMAPHPNMPGSQMRLPGFAGMINSEMEGPNVPNPASRPGLSG 589 G + + P P+G A P G + +PG P PA + G +G Sbjct: 572 GARGQAGVMGFP---GPKGAAGEPGKAG-ERGVPG----------PPGAVGPAGKDGEAG 617 Query: 590 VSWPDDVPKIPDGRNFPPGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAM 649 P P P G QG PG + P P G PPG A Sbjct: 618 AQGPPG-PAGPAGER--GEQGPAGSPG-FQGLPGPAG-----------------PPGEA- 655 Query: 650 EGIRPSMEMNRMIPGSQRHMEPGNNPIFPRIPVEGPLSPSRGDFPKGIPPQMG----PGR 705 +PG + + GP S +RG+ +G P + G PG Sbjct: 656 -------------------GKPGEQGVPGDLGAPGP-SGARGE--RGFPGERGVQGPPG- 692 Query: 706 ELEFGMVPSGMKGDVNLNVNMGSNSQMIPQKMREAGAGPEEMLKLRPGGSDMLPAQQKMV 765 P+G +G N G+ +AGA + PG M P ++ Sbjct: 693 -------PAGPRGANGAPGNDGAKG--------DAGAPGAPGSQGAPGLQGM-PGERGAA 736 Query: 766 PLPFGEHPQQEYG-MGPRPFLPMSQGPGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNP 824 LP P+ + G GP+ + G G+R L PIGP + P P Sbjct: 737 GLP---GPKGDRGDAGPKG----ADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGP 789 Query: 825 SSNPTSLNTAPPVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGSP-SGNL 883 + PT AP RG P AG PG + Q G P Sbjct: 790 -AGPTGARGAPG-DRGEPGPPGPAGFAG----PPGADG---------QPGAKGEPGDAGA 834 Query: 884 KSPQTPSQLAGMLAGPAAAASIKSPPVLGS--AAASPVHLKSPSL------PAPSPGWTS 935 K P AG P ++ +P G+ +A P P P PS G Sbjct: 835 KGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPS-GNAG 893 Query: 936 SPKPPLQSPGIPPNHKAPLTMASPA-MLGNVESGGPPPPTASQPASVNIPGSLPSSTPYT 994 P PP P K P PA G V GPP P A + S G P+ P T Sbjct: 894 PPGPP--GPAGKEGGKGPRGETGPAGRPGEVGPPGPPGP-AGEKGSPGADG--PAGAPGT 948 Query: 995 MPPEPTLSQNPLSIMMSRMSKFAMPS-STPLYHDAIKTVASSDDDSPPARSPNLPSMNNM 1053 P+ Q + + + + P P + + + + P P + Sbjct: 949 PGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGP 1008 Query: 1054 PGMGINTQNPRISG-PNPVVPMPTLSPMGMTQPLSHSNQMPSPNAVGPNIPPHGV----- 1107 PG P G P G T P +P A GP + P G Sbjct: 1009 PGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGP-VGPAGKSGDRG 1067 Query: 1108 ---PMGPGLMSHNPIMGHGSQEP--PMVPQGRMGFP-----------QGFPPVQSPP--- 1148 P GP P+ G++ P P P+G G +GF +Q PP Sbjct: 1068 ETGPAGPA----GPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPP 1123 Query: 1149 ----QQVPFPHNGPSGGQGSFPGGMGFPGE-------GPLGRPSNLPQSSADAALCKPGG 1197 +Q P +GP+G +G PG G PG+ GP+G P + + DA P G Sbjct: 1124 GSPGEQGPSGASGPAGPRGP-PGSAGAPGKDGLNGLPGPIGPPGPRGR-TGDAGPVGPPG 1181 Query: 1198 PGGP 1201 P GP Sbjct: 1182 PPGP 1185 Score = 62.4 bits (150), Expect = 3e-09 Identities = 97/338 (28%), Positives = 115/338 (34%), Gaps = 35/338 (10%) Query: 1101 NIPPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPSG 1160 N P VP G P+ GS+ P + P+G + P P Sbjct: 80 NCPGAEVPEGECC----PVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIP 135 Query: 1161 GQGSFPGGMGFPGE-GPLGRPSNL-PQ--------SSADAALCKPGGPGGPDSFT-VLGN 1209 GQ PG G PG GP G N PQ S+ ++ P GP GP G Sbjct: 136 GQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGA 195 Query: 1210 SMPSVFTDPDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEV--PGRKQPQGPG 1267 P F P E PGA+G + P P + GE PGR +GP Sbjct: 196 PGPQGFQGPP-GEPGEPGASG-------PMGPRGPPGPPGKNGDDGEAGKPGRPGERGP- 246 Query: 1268 PGFSHMQGMMGEQAPRMGLALPGMGGPGPVGTPDIPLGTA-PSMPGHNPMRPPAFLQQGM 1326 PG +G+ G LPGM G D G A P+ P P P G Sbjct: 247 PGPQGARGLPGTAG------LPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQ 300 Query: 1327 MGPHHRMMSPAQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGLYTHPGPVGSPGMM--MSM 1384 MGP + PG N A P GPAG PG VG+ G Sbjct: 301 MGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGP 360 Query: 1385 QGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 +G GPQ P P G A G G PG G Sbjct: 361 RGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKG 398 Score = 61.2 bits (147), Expect = 7e-09 Identities = 200/872 (22%), Positives = 259/872 (29%), Gaps = 133/872 (15%) Query: 30 PPTVMSPSGNPQLDSKFSNQGKQGGSASQSQPSPCDSKSGGHTPKALPGPGGSMGLKNGA 89 P P+GNP D + +G G P G P GPGG G K + Sbjct: 378 PAGAAGPAGNPGADGQPGAKGANGAPGIAGAPG----FPGARGPSGPQGPGGPPGPKGNS 433 Query: 90 GNGAKGKGKRERSISADSFDQRDPGTPNDDSDIKECNSADHIKSQDSQHTPHSMTPSNAT 149 G +PG P D + Q P+ Sbjct: 434 G---------------------EPGAPGSKGDTGAKGEPGPVGVQGPPG------PAGEE 466 Query: 150 APRSSTPSHGQTTATEPTPAQKTPAKVVYVFSTEMANKAAEAVLKGQVETIVSFHIQNIS 209 R + G T P + P + + +A A +G + Sbjct: 467 GKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEA 526 Query: 210 NNKTERSTAPLNTQISALRNDPKPLPQQ-PPAPANQDQNSSQNTRLQPTPPIPA------ 262 E P ++ P P + PP PA QD +P PP P Sbjct: 527 GRPGEAGL-PGAKGLTGSPGSPGPDGKTGPPGPAGQDG--------RPGPPGPPGARGQA 577 Query: 263 -----PAPKPAA--PPRPLDRESPGVENKLIPSVGSPASSTPLPPDGTGPNSTPNNR--A 313 P PK AA P + +R PG + P+ + PP GP + A Sbjct: 578 GVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPA 637 Query: 314 VTPVSQGSNSSSADPKAPPPPPVSSGEPPTLGENPD-GLSQEQLEHRERSLQTLRDIQRM 372 +P QG P PP +G+P G D G ER R +Q Sbjct: 638 GSPGFQGL-------PGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGP 690 Query: 373 LFPDEKEFTGAQSG--GPQQNPGVLDGPQKKPEGPIQAMMAQSQSLGKGPGPRTDVG--- 427 P G G + + G P + +Q M + + G PGP+ D G Sbjct: 691 PGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGL-PGPKGDRGDAG 749 Query: 428 -----------------APFGPQGHRDVPFSPDEMVPPSMNSQSGTIG-PDHLDHMTPEQ 469 P GP G P E P +G G P P Sbjct: 750 PKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPG 809 Query: 470 IAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVV--RGPPPPYQMTPSEGW- 526 A + K E GP G GPP P + G Sbjct: 810 PAGFAGPPGADGQPGAKGEPGDAGAKG-------DAGPPGPAGPAGPPGPIGNVGAPGAK 862 Query: 527 ------APGGTEPFSDGINMPHSLPPRGMAPHPNMPGSQMRLPGFAGMINS-------EM 573 P G F P G A P PG + G + E+ Sbjct: 863 GARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEV 922 Query: 574 EGPNVPNPASRPGLSGVSWPDDVPKIPDGRNFPPGQGIFSGPG-RGER-FPNPQGLSEEM 631 P P PA G G P P P + +G+ PG RGER FP G S E Sbjct: 923 GPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEP 982 Query: 632 FQQ--QLAEKQLGLPPGMAMEGIR--PSMEMNRMIPGSQRHMEPGNNPIFPRIPVE-GPL 686 +Q A + G P M G+ P PG++ +P E GP Sbjct: 983 GKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPA 1042 Query: 687 SPSRGDFPKGIPPQMGP-GRELEFGMV-PSGMKGDVNLNVNMGSNSQMIPQKMR----EA 740 P G P +GP G+ + G P+G G V +G+ PQ R E Sbjct: 1043 GPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVG---PVGARGPAGPQGPRGDKGET 1099 Query: 741 GAGPEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQQEYG-MGPRPFLPMSQGPGSNSGLRN 799 G + +K G S L P + P G GPR P S G GL Sbjct: 1100 GEQGDRGIKGHRGFSG-LQGPPGPPGSPGEQGPSGASGPAGPRG-PPGSAGAPGKDGLNG 1157 Query: 800 LREPIGPD---QRTNSRLSHMPPLPLNPSSNP 828 L PIGP RT PP P P P Sbjct: 1158 LPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPP 1189 Score = 40.8 bits (94), Expect = 0.009 Identities = 61/234 (26%), Positives = 74/234 (31%), Gaps = 33/234 (14%) Query: 234 LPQQPPAPANQDQNSSQNTRLQPTPPIPAPAPKPAAPPRPLDRE-SPGVENKLIPSVGSP 292 LP P Q + + R PP P P A PP RE +PG E GSP Sbjct: 975 LPGPSGEPGKQGPSGASGER---GPPGPMGPPGLAGPPGESGREGAPGAEGSPGRD-GSP 1030 Query: 293 ASSTPL-------PPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPP--PVSSGEPPT 343 + PP G P V P + + P P P PV + P Sbjct: 1031 GAKGDRGETGPAGPPGAPGAPGAPG--PVGPAGKSGDRGETGPAGPAGPVGPVGA-RGPA 1087 Query: 344 LGENPDGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPGVLDGPQKKPE 403 + P G E E +R ++ R + P G +Q P GP Sbjct: 1088 GPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPP-----GPPGSPGEQGPSGASGPAGPRG 1142 Query: 404 GPIQAMMAQSQSLGKGPGP--------RTDVGAPFGPQGHRDVPFSPDEMVPPS 449 P A L PGP RT P GP G P P PPS Sbjct: 1143 PPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPG---PPS 1193 >gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] Length = 1626 Score = 101 bits (251), Expect = 6e-21 Identities = 297/1239 (23%), Positives = 392/1239 (31%), Gaps = 249/1239 (20%) Query: 332 PPPPVSSGEPPTLGENPDGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQN 391 PPPP PPT G G L+ I EK G GP Sbjct: 451 PPPPPPPQRPPTPGSEQIGF--------------LKTINCSCPAGEKGEMGV--AGPMGL 494 Query: 392 PGVLDGPQKKPEGPIQAM--------MAQSQSLGKGP------GPRTDVGAPFGP--QGH 435 PG P+G I A+ + +G GP G + +G P P G Sbjct: 495 PG--------PKGDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGS 546 Query: 436 RDVPFSPDEMVPPSMNSQSGTIGPDHLDHM--TPEQIAWLKLQQEFYEEKRRKQEQVVVQ 493 + + P E+ P + + G GP + P ++ LQ E E+ R ++ Sbjct: 547 KGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEK----G 602 Query: 494 QCSLQDM--------MVHQHGPRGVVRGPPPPYQMTPSEGWAPGGTEPFSDGINMPHSLP 545 + L + GP GV + P+ G+ +G+ P Sbjct: 603 ERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAP 662 Query: 546 -PRGMAPHPNMPGSQMRL--------PGFAGM--INSEMEGPNVP------NPASRPGLS 588 PRG P PG++ + PG G+ +M P +P P PG+ Sbjct: 663 GPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVP 722 Query: 589 GVSWPDDVPKIP--------------------DGRNFPPG-QGIFSGPG-RGE-RFPNPQ 625 G P P +P DG N PPG G PG RGE P Sbjct: 723 GPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKP 782 Query: 626 GLSEEMFQQQLAEK-----QLGLPPGMAMEGIR--------------PSMEMNRMIPGSQ 666 GL E+ +Q LA + + GLP G+R P ++ +R G Sbjct: 783 GLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEA 842 Query: 667 RHME----PGNNPIF---PRIPVEGPLSPSRGDFPKGIPPQMG-PGRELEFGMVPSGMKG 718 PG +F PR+P E +GD G+P + G GR E G P G G Sbjct: 843 GPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGD--PGLPGEPGLQGRPGELG--PQGPTG 898 Query: 719 DVNLNVNMGSNSQMIPQKMREAGAGPEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQQEYG 778 G++ P GA P + P G + P + + E G Sbjct: 899 PPGAKGQEGAHG--APGAAGNPGA-PGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKG 955 Query: 779 MGPRPFLPMSQGPGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQ 838 P GP + G L P G + L P LP P A Sbjct: 956 AAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLP-----GPLGTKAACGKV 1010 Query: 839 RGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGMLAG 898 RG L +PGI SP G P + P PS G Sbjct: 1011 RGSENCALGGQCVKGDRGAPGIP--GSPGSR-------GDPGIGVAGPPGPSGPPGDKGS 1061 Query: 899 PAAAASIKSPPVLGSAAASPVHLKSPSLPAP-SPGWTSSPKPPLQSPGIPP--------- 948 P + P G A AP +PG P P S + P Sbjct: 1062 PGSRGLPGFPGPQGPAGRD---------GAPGNPGERGPPGKPGLSSLLSPGDINLLAKD 1112 Query: 949 --NHKAPLTMASPAMLGNVESGGPPPPTASQPASVNIPGSLPSSTPYTMPPEPTLSQNPL 1006 N P P + G G P +P G + P +P P ++ P Sbjct: 1113 VCNDCPPGPPGLPGLPGFKGDKGVP----GKPGREGTEGKKGEAGPPGLPGPPGIA-GPQ 1167 Query: 1007 SIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMGINTQNPRIS 1066 R + + H + + P + + P GI + Sbjct: 1168 GSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPP--GIQGSPGKEG 1225 Query: 1067 GPNPVVPMPTLSPMGMTQPLSHSNQMPSPNAVG----PNIP-PHGVPMGPGLMSHNPIMG 1121 P P P G + P G P +P P G PG H G Sbjct: 1226 PPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHT---G 1282 Query: 1122 HGSQEPPMVPQGRMGFP--QGFPPVQSPP----QQVPFPHNGPSGGQGSFPGGMGFPGEG 1175 P G MG P +G P Q P GP G GS PG G P G Sbjct: 1283 DSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGS-PGSPGEP--G 1339 Query: 1176 PLGRPSNLPQSSADAALCKPG--GPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGATGIPE 1233 P G P + + PG GP GP P P + V PG G P Sbjct: 1340 PSGTPGQKGSKGENGSPGLPGFLGPRGPP-------GEPGEKGVPGKEGV--PGKPGEPG 1390 Query: 1234 FDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPG-PGFSHMQGMMGEQAPRMGLALPG-- 1290 F R P K +G G+ QP PG PG G+MG Q LPG Sbjct: 1391 FKGERGDPGIKGD-------KGPPGGKGQPGDPGIPGHKGHTGLMGPQ------GLPGEN 1437 Query: 1291 --MGGPGPVGTPDIP--LGTAPSMPGHNPM-------------------RPPAFLQ--QG 1325 +G PGP G P P G +PSM + PPA+++ QG Sbjct: 1438 GPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQG 1497 Query: 1326 MMGPHHRMMSPAQSTMPGQPTLMSNPA-AAVGMIPGKDRGPAGLYTHPGPVGSPGMM-MS 1383 GP P + +PG+ M P G + G GP G G G PG + Sbjct: 1498 RPGPPG---PPGKDGLPGRAGPMGEPGRPGQGGLEGPS-GPIGPKGERGAKGDPGAPGVG 1553 Query: 1384 MQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 ++G MGP IP Q G A D G+ G G G Sbjct: 1554 LRGEMGPPG---IPGQPGEPGYAKD-GLPGIPGPQGETG 1588 Score = 97.8 bits (242), Expect = 6e-20 Identities = 304/1255 (24%), Positives = 399/1255 (31%), Gaps = 327/1255 (26%) Query: 231 PKPLPQQPPAPANQDQNSSQNTRLQPTPPIPAPAPKPAAPPRPLDRESPGVENKLIPSVG 290 P P PQ+PP P ++ + PA P+ P + I VG Sbjct: 453 PPPPPQRPPTPGSEQIGFLKTINCS----CPAGEKGEMGVAGPMGLPGPKGDIGAIGPVG 508 Query: 291 SPA-----SSTPLPPDGTGPNSTPNNRAVT--PVSQGSNSSSADP--------------K 329 +P + P G G + + P GS +P + Sbjct: 509 APGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMR 568 Query: 330 APPPPPVSSGEPPTLGENPDGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQ 389 P PP G P +G GL E+ E R + R + FP + TG Q G P Sbjct: 569 GPQGPPGLPGPPGRVGA--PGLQGERGEKGTRGEKGERGLDG--FPGKPGDTG-QQGRP- 622 Query: 390 QNPGVLDGPQKK-----PEGP--IQAMMAQSQSLGKGPGPRTDVGAPFGPQGHRDVPFSP 442 P + GPQ + P GP + + Q + L + + GAP GP+GH+ P P Sbjct: 623 -GPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGL------KGEQGAP-GPRGHQGAPGPP 674 Query: 443 DEMVPPSMNSQSGTIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMV 502 G IGP+ D P + L+ ++ DM Sbjct: 675 ---------GARGPIGPEGRDG--PPGLQGLRGKKG--------------------DM-- 701 Query: 503 HQHGPRGV-----VRGPPPPYQMTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPG 557 GP G+ ++GPP P PG P P PG Sbjct: 702 ---GPPGIPGLLGLQGPPGP----------PG--------------------VPGPPGPG 728 Query: 558 SQMRLPGFAGMINSEMEGPNVPNPASRPGLSGVSWPDDVPKIPDGRNFPPGQGIFSGPGR 617 LPG G P P P PG G P+G PPG G Sbjct: 729 GSPGLPGEIGFPGK----PGPPGPTGPPGKDG----------PNGPPGPPGTKGEPGERG 774 Query: 618 GERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIF 677 + P GL E+ +Q LA RP + +PG+ P F Sbjct: 775 EDGLPGKPGLRGEIGEQGLAG--------------RPGEKGEAGLPGA---------PGF 811 Query: 678 PRIPVEGPLSPSRGDFPKGIPPQMGPGRELEFGMVPSGMKGDVNLNVNMGSNSQMIPQKM 737 P + E +GD G + E G+ G+KGD + Sbjct: 812 PGVRGE------KGD----------QGEKGELGL--PGLKGDRG--------------EK 839 Query: 738 REAGAGPEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQQEYGMGPR-----PFLPMSQGPG 792 EAG P G LP + F HP+ GP+ P LP G Sbjct: 840 GEAG----------PAGPPGLPGTTSL----FTPHPRMPGEQGPKGEKGDPGLPGEPGLQ 885 Query: 793 SNSGLRNLREPIGPDQRTNSRLSHMPPLPLN------------PSSNPTSLNTAPPVQRG 840 G + P GP +H P PS P S+ P RG Sbjct: 886 GRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGA--PGLRG 943 Query: 841 LGRKPLDISVAGS--QVHSPG-INPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGMLA 897 K + G+ + SPG + P P +P L P G K + + + L Sbjct: 944 TPGKDGERGEKGAAGEEGSPGPVGPRGDPG-----APGLPGPPGKGKDGEPGLRGSPGLP 998 Query: 898 GP----AAAASIKSPP--VLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHK 951 GP AA ++ LG +P +P SPG S P + G P Sbjct: 999 GPLGTKAACGKVRGSENCALGGQCVKGDR-GAPGIPG-SPG--SRGDPGIGVAGPPGPSG 1054 Query: 952 APLTMASPAMLGNVESGGPPPPTASQPASVNIPGSLPSSTPYTMPPEPTLSQNPLSIMMS 1011 P SP G GP P A PG+ P P +P LS Sbjct: 1055 PPGDKGSPGSRGLPGFPGPQGPAGRDGA----PGNPGERGP---PGKPGLSS-------- 1099 Query: 1012 RMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMGINTQNPRISGPNPV 1071 P L K V + PP P LP G+ G Sbjct: 1100 ----LLSPGDINLL---AKDVCNDCPPGPPGL-PGLPGFKGDKGVPGKPGREGTEGKKGE 1151 Query: 1072 VPMPTL-SPMGMTQPLSHSNQMPSPNAVGPNIPPHGVPMGPGLMSHNPIMGHGSQEPPMV 1130 P L P G+ P + + VG G P PG M G+ PP Sbjct: 1152 AGPPGLPGPPGIAGPQGSQGERGADGEVGQK-GDQGHPGVPGFMGPP-----GNPGPPGA 1205 Query: 1131 P--QGRMGFP--QGFPPVQSPPQQVPFPHNGPSGGQGSFPGGMGFPGEGPLGRPSNLPQS 1186 G G P QG P + PP GPSG G PG G G P P Sbjct: 1206 DGIAGAAGPPGIQGSPGKEGPPGP-----QGPSGLPG-IPGEEGKEGRDGKPGPPGEPGK 1259 Query: 1187 SADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGATGIPEFDLSRIIPSEKPS 1246 + + L P G GP F G++ S P + GA G+P Sbjct: 1260 AGEPGLPGPEGARGPPGFK--GHTGDSGAPGPRGES----GAMGLP-------------- 1299 Query: 1247 QTLQYFPRGEVPGRKQPQGP-GPGFSHMQGMMGEQAPRMGLALPGM-GGPGPVGTP---- 1300 + +PG+ GP GP QG G + P PG G PGP GTP Sbjct: 1300 ------GQEGLPGKDGDTGPTGP-----QGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKG 1348 Query: 1301 DIPLGTAPSMPGH-NPMRPPAFLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAAAVGMIP 1359 +P +PG P PP + G G + P + PG +P I Sbjct: 1349 SKGENGSPGLPGFLGPRGPPG--EPGEKGVPGKEGVPGKPGEPGFKGERGDPG-----IK 1401 Query: 1360 GKDRGPAGLYTHPGPVGSPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGF 1414 G D+GP G PG G PG G+MGPQ +P + P G G GF Sbjct: 1402 G-DKGPPGGKGQPGDPGIPG-HKGHTGLMGPQG---LPGENGPVGPPGPPGQPGF 1451 Score = 62.0 bits (149), Expect = 4e-09 Identities = 113/444 (25%), Positives = 152/444 (34%), Gaps = 89/444 (20%) Query: 1031 TVASSDDDSPPARSPNLPSMNNMPGMG-INTQNPRISGPNPVVPMPTLSPMGMTQPLSHS 1089 TV + PP + P P + + IN P M PMG+ P Sbjct: 446 TVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPA----GEKGEMGVAGPMGLPGPKGDI 501 Query: 1090 NQMPSPNAVGPN-------IPPHG-----------VPMGPGLMSHNPIMGHGSQ--EPPM 1129 + A GP I P G +P PG + G + EP + Sbjct: 502 GAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGL 561 Query: 1130 VPQGRMGFPQGFPPVQSPPQQVPFPHNGPSGGQGSFPGGMGFPGEGPLGRPSNLPQSSAD 1189 + M PQG P + PP +V P G G +G G G GE L P + Sbjct: 562 PGEVGMRGPQGPPGLPGPPGRVGAP--GLQGERGE-KGTRGEKGERGLDGFPGKPGDTGQ 618 Query: 1190 AALCKPGGPGGPDSFT-VLGNSMPSVFTDPDLQEVIRPGATGIPEFDLSRIIPSEKPSQT 1248 P G GP +G + P +Q+ G G P Sbjct: 619 QGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPG--------------- 663 Query: 1249 LQYFPRGE-----VPGRKQPQGP-----GPGFSHMQGMMGEQAPRMGLALPGM----GGP 1294 PRG PG + P GP PG ++G G+ P +PG+ G P Sbjct: 664 ----PRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPP---GIPGLLGLQGPP 716 Query: 1295 GPVGTPDIP-LGTAPSMPGH----------NPMRPPA-FLQQGMMGPHHRMMSP---AQS 1339 GP G P P G +P +PG P PP G GP P + Sbjct: 717 GPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGED 776 Query: 1340 TMPGQPTLMSN-PAAAVGMIPGKDRGPAGLYTHPGPVGSPGMMMSMQGMMGPQQNIMIPP 1398 +PG+P L + PG ++G AGL PG G PG + +G G + + +P Sbjct: 777 GLPGKPGLRGEIGEQGLAGRPG-EKGEAGL---PGAPGFPG-VRGEKGDQGEKGELGLPG 831 Query: 1399 QMRPRGMAADVGMGGFSQGPGNPG 1422 RG + G G PG PG Sbjct: 832 LKGDRGEKGEAGPAG---PPGLPG 852 Score = 57.0 bits (136), Expect = 1e-07 Identities = 221/944 (23%), Positives = 293/944 (31%), Gaps = 195/944 (20%) Query: 292 PASSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGEPPTLGEN---- 347 PA LP GT TP+ R P QG DP P P + G P LG Sbjct: 844 PAGPPGLP--GTTSLFTPHPRM--PGEQGPKGEKGDPGLPGEPGLQ-GRPGELGPQGPTG 898 Query: 348 PDGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPGVLDGPQKKPEGPIQ 407 P G ++ H P GA GP PG + P + Sbjct: 899 PPGAKGQEGAHGAPGAAGN--------PGAPGHVGAP--GPSGPPGSVGAPGLRGTPGKD 948 Query: 408 AMMAQSQSLGKGPGPRTDVGAPFGPQGHRDVPFSPDEMVPPSM--NSQSGTIGPDHLDHM 465 + + G+ P GP G R P +P PP + + G G L Sbjct: 949 GERGEKGAAGEEGSP--------GPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGP 1000 Query: 466 TPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDM----MVHQHGPRGV----VRGPPPP 517 + A K+ R + + QC D + G RG V GPP P Sbjct: 1001 LGTKAACGKV--------RGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGP 1052 Query: 518 YQMTPSEGWAPGGTEPFSDGI-NMPHSLPPRGMAPHPNMPG----------SQMRLPGFA 566 P + +PG S G+ P P G P PG S + PG Sbjct: 1053 -SGPPGDKGSPG-----SRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDI 1106 Query: 567 GMINSEMEGPNVPNPASRPGLSGVSWPDDVPKIPDGRNFPPGQGIFSGPGRGERFPNPQG 626 ++ ++ P P PGL G VP P GR G+ +GP P P G Sbjct: 1107 NLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKP-GREGTEGKKGEAGP---PGLPGPPG 1162 Query: 627 LSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIFPRIPVEGPL 686 ++ Q ++ + G + +G ++ PG M P NP P G Sbjct: 1163 IAGP----QGSQGERGADGEVGQKG-------DQGHPGVPGFMGPPGNPGPP-----GAD 1206 Query: 687 SPSRGDFPKGIPPQMGPGRELEFG-MVPSGMKGDVNLNVNMGSNSQMIPQ----KMREAG 741 + P GI Q PG+E G PSG+ G G + + P K E G Sbjct: 1207 GIAGAAGPPGI--QGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPG 1264 Query: 742 AGPEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPMSQGPGSNSGLRNLR 801 E + PG P P GE G+ + LP G +G + + Sbjct: 1265 LPGPEGARGPPGFKGH--TGDSGAPGPRGESGAM--GLPGQEGLPGKDGDTGPTGPQGPQ 1320 Query: 802 EPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLDISVAGSQVHSPGIN 861 P GP + S P P P + T P Q+G + + SPG+ Sbjct: 1321 GPRGPPGKNGS-----PGSPGEPGPSGT------PGQKG----------SKGENGSPGLP 1359 Query: 862 PLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHL 921 P + G P G P P + P P + G Sbjct: 1360 GFLGPRGPPGEPGEKGVP-GKEGVPGKPGE-------PGFKGERGDPGIKGD-------- 1403 Query: 922 KSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMASPAMLGNVESGGPPPPTASQPASV 981 K P PG P PGIP HK + P L PP QP Sbjct: 1404 KGP------PGGKGQPG----DPGIP-GHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFP 1452 Query: 982 NIPGSLPSSTPYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPP 1041 + G PS M L Q L + + + P Y + SS P Sbjct: 1453 GLRGESPS-----METLRRLIQEELGKQLETRLAYLLAQMPPAY------MKSSQGRPGP 1501 Query: 1042 ARSPNLPSMNNMPGMGINTQNPRISGPNPVVPMPTLSPMGMTQPLSHSNQMPSPNAVGPN 1101 P P + +PG P G + P G P P A G Sbjct: 1502 ---PGPPGKDGLPGRAGPMGEPGRPGQGGLE-----GPSGPIGPKGERGAKGDPGAPGVG 1553 Query: 1102 I----PPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNG 1157 + P G+P PG EP G G P P G Sbjct: 1554 LRGEMGPPGIPGQPG-------------EPGYAKDGLPGIPG------------PQGETG 1588 Query: 1158 PSGGQGSFPGGMGFPGEGPLGRPSNLPQSSADAALCKPGGPGGP 1201 P+G G PG G PG+ PS ++ AA +PG GP Sbjct: 1589 PAGHPG-LPGPPGPPGQCD---PSQCAYFASLAA--RPGNVKGP 1626 Score = 47.8 bits (112), Expect = 8e-05 Identities = 100/424 (23%), Positives = 143/424 (33%), Gaps = 80/424 (18%) Query: 233 PLPQQPPA-PANQDQNSSQNTRLQPTPP-IPAPAPKPAAPPRPLDRESPGVENKLIPSVG 290 P PQ P P + + +P PP P A +P P R PG + Sbjct: 1227 PGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGH------ 1280 Query: 291 SPASSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSAD--PKAPPPPPVSSGEPPTLGE-N 347 + S P P +G P + P G + P+ P PP +G P + GE Sbjct: 1281 TGDSGAPGPRGESGAMGLPGQEGL-PGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPG 1339 Query: 348 PDGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPGVLDGPQKK--PEGP 405 P G ++ E P F G + GP PG P K+ P P Sbjct: 1340 PSGTPGQKGSKGENG-----------SPGLPGFLGPR--GPPGEPGEKGVPGKEGVPGKP 1386 Query: 406 IQAMMAQSQSLGKGPGPRTDVGAPFGPQGHRDVPFSPDE------MVPPSMNSQSGTIGP 459 + + PG + D G P G +G P P M P + ++G +GP Sbjct: 1387 GEPGFKGERG---DPGIKGDKGPP-GGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGP 1442 Query: 460 ---------DHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGV 510 L +P +L QE ++ + ++ Q M Q P Sbjct: 1443 PGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRP--- 1499 Query: 511 VRGPPPPYQMTPSEGWAPGGTEPFSD-------GINMPHS-LPPRGMAPHPNMPGSQMRL 562 GPP P P + PG P + G+ P + P+G PG+ Sbjct: 1500 --GPPGP----PGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGA---- 1549 Query: 563 PGFAGMINSEMEGPNVPNPASRPGLSGVSWPDDVPKIPDGRNFPPGQGIFSGPGRGERFP 622 PG + EM P +P PG + D +P IP P G+ +GP P Sbjct: 1550 PGVG--LRGEMGPPGIPGQPGEPGYA----KDGLPGIPG----PQGE---TGPAGHPGLP 1596 Query: 623 NPQG 626 P G Sbjct: 1597 GPPG 1600 Score = 46.6 bits (109), Expect = 2e-04 Identities = 65/232 (28%), Positives = 90/232 (38%), Gaps = 30/232 (12%) Query: 1205 TVLGNSM-PSVFTDPDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQP 1263 TV+G + SV D DLQ ++ + E + IPS T+ P P ++ P Sbjct: 402 TVIGKRLYDSVPIDFDLQRIVIYCDSRHAELETCCDIPSGPCQVTVVTEPPPPPPPQRPP 461 Query: 1264 QGPGP---GF------SHMQGMMGEQAPRMGLALPG----MGGPGPVGTPDIPLGTAPSM 1310 PG GF S G GE + LPG +G GPVG P P G + Sbjct: 462 T-PGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPG-PKGEKGDV 519 Query: 1311 PGHNPMRPPAFLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGLYT 1370 G P ++G +G M G+P + P + +GP GL Sbjct: 520 -GIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPG 578 Query: 1371 HPGPVGSPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 PG VG+PG +QG G + RG + G+ GF PG+ G Sbjct: 579 PPGRVGAPG----LQGERG---------EKGTRGEKGERGLDGFPGKPGDTG 617 Score = 30.8 bits (68), Expect = 9.7 Identities = 24/92 (26%), Positives = 32/92 (34%), Gaps = 7/92 (7%) Query: 30 PPTVMSPSGNPQLDSKFSNQGKQGGSASQSQPSPCDSKSGGHTPKALPGPGGSMGLKNGA 89 PP PSG P + + +G+ G +P K+G LPGP G+ G Sbjct: 1226 PPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEP----GKAG---EPGLPGPEGARGPPGFK 1278 Query: 90 GNGAKGKGKRERSISADSFDQRDPGTPNDDSD 121 G+ R S G P D D Sbjct: 1279 GHTGDSGAPGPRGESGAMGLPGQEGLPGKDGD 1310 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 98.6 bits (244), Expect = 4e-20 Identities = 293/1177 (24%), Positives = 376/1177 (31%), Gaps = 270/1177 (22%) Query: 384 QSGGPQQNPGVLDGPQKKPEGPIQAMMAQSQSLGKGPGPRTDVGAPFGPQGHRDVPFSPD 443 Q G P P V+ G + +P GP +Q +GP R P G G VP P Sbjct: 114 QKGEPGLVP-VVTGIRGRP-GPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPG 171 Query: 444 EMVPPSMNSQSGTIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVH 503 PP S G PD L Q+A L +EK QV + S+ + Sbjct: 172 APGPPGHPSHPG---PDGLSRPFSAQMAGL-------DEKSGLGSQVGLMPGSVGPV--- 218 Query: 504 QHGPRGVVRGPPPPYQMTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPGSQMRLP 563 GPRG P + +G A G T P P PG P Sbjct: 219 --GPRG-------PQGLQGQQGGA-GPTGP-------------------PGEPGD----P 245 Query: 564 GFAGMINSEMEGPNVPNPASRPGLSGVSWPDDVPKIPDGRNFPPGQGIFSGPGRGERFPN 623 G G I S GP P +PG G GRN PG+ F+G FP Sbjct: 246 GPMGPIGSR--GPE--GPPGKPGEDG----------EPGRNGNPGEVGFAGSPGARGFPG 291 Query: 624 PQGLSEEMFQQQLAEKQLGLPPGMAMEGIR-PSMEMNRMIPGSQRHMEPGNNPIFPRIPV 682 GL GL +G+ P E+ PGS+ P + Sbjct: 292 APGLP-------------GLKGHRGHKGLEGPKGEVGA--PGSKGEAGPTGP-----MGA 331 Query: 683 EGPLSP-----SRGDF-PKGIPPQMG----PGRELEFGMVPSGMKGDVNLNVNMGSNSQM 732 GPL P RG P+G P Q G PG+ G P G+ G N G + Sbjct: 332 MGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMG--PLGIPGSSGFPGNPGMKGEA 389 Query: 733 IPQKMREAGAGPEEMLKLR--------------PG--GSDMLPAQQKMVPLPFGEHPQQE 776 P R GPE R PG G+D P + P P Sbjct: 390 GPTGAR----GPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGS 445 Query: 777 YG----------MGPR-----------PFLPMSQGPGSNSGLRNLREPIGPDQRTNSRLS 815 G GP+ P GP G ++ PIGP R Sbjct: 446 AGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKR-- 503 Query: 816 HMPPLPLNPSSNPTSLNTAPPV-QRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSP 874 P +P ++ PV +RG A PG + L P Q + Sbjct: 504 -------GPRGDPGTVGPPGPVGERG----------APGNRGFPGSDGLPGPKGAQGERG 546 Query: 875 MLGS--PSGNLKSPQTPSQ--LAGMLA--------------GPAAAASIKSPPVLGSAAA 916 +GS P G+ P P + L G GP A P G + Sbjct: 547 PVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRP--GPPGS 604 Query: 917 SPVHLKSPSLPAPSP-GWTSSPKPPLQS--PGIPPNHKAPLT---------MASPAMLGN 964 + + S+ P P G + P P ++ G+P AP + P + G Sbjct: 605 IGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGE 664 Query: 965 VESGGPPPPTASQ--PASVNIPGSLPSSTPYTMPPEPTLSQNPLSIMMSRMS--KFAMPS 1020 GPP PT Q P PG +P +P + PL R + + P Sbjct: 665 RGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPG-AVGPLGPRGERGNPGERGEPG 723 Query: 1021 STPLYHDAIKTVASSDDDSPPARSPN---LPSMNNMPGM-GINTQNPRISGPNPVVPMPT 1076 T L + K +A P SP P PG+ G+ + P P Sbjct: 724 ITGLPGE--KGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGG 781 Query: 1077 LSPMGMTQPLSHSNQMPSPNAVGPNIPP-----HGVPMGPGLMSHNPIMGHGSQEPPMVP 1131 + G + P +GP P G P GL+ G+ P Sbjct: 782 IGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGP 841 Query: 1132 QGRMGF-----PQGFPPVQSPPQQV-----------------PFPHN-----GPSGGQGS 1164 G +GF P G P V+ P + P PH G GG+G+ Sbjct: 842 TGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGT 901 Query: 1165 F--PGGMGFPGE-------GPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVF 1215 PG GFPG GP G P PG G P S +G+ P+ Sbjct: 902 QGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPA-- 959 Query: 1216 TDPDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEV--PGRKQPQGPGPGFSHM 1273 P PG G P D + P P RG V PG++ +G PG Sbjct: 960 GPPG-----GPGDKGDPGED-GQPGPDGPPGPAGTTGQRGIVGMPGQRGERGM-PGLPGP 1012 Query: 1274 QGMMGEQAPRMGLALPGMGGPGPVGTPDI--PLGT-APSMPGHN---PMRPPAFLQQGMM 1327 G G+ P A G PGPVG P P+G P P N P R A ++G Sbjct: 1013 AGTPGKVGPTG--ATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDR 1070 Query: 1328 GPHHRMMSPAQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGLYTHPGPVGSPGM--MMSMQ 1385 G P PG P P A G D G G GP+G PG + Sbjct: 1071 GDPGPAGLPGSQGAPGTP----GPVGAPG-----DAGQRGDPGSRGPIGPPGRAGKRGLP 1121 Query: 1386 GMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 G GP+ + RG G G PG PG Sbjct: 1122 GPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPG 1158 Score = 96.7 bits (239), Expect = 1e-19 Identities = 320/1255 (25%), Positives = 396/1255 (31%), Gaps = 267/1255 (21%) Query: 282 ENKLIPSV----GSPASSTPLPPDGT----GPNSTPNNRAVTPVSQGSNSSSADPKAPPP 333 E L+P V G P + P G GP P R + G P AP P Sbjct: 117 EPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGID-GEPGVPGQPGAPGP 175 Query: 334 PPVSSGEPPTLGENPDGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPG 393 P G P G PDGLS R S Q M DEK G+Q G + G Sbjct: 176 P----GHPSHPG--PDGLS------RPFSAQ-------MAGLDEKSGLGSQVGLMPGSVG 216 Query: 394 VLDGPQKKPEGPIQAMMAQSQSLGKGP-GPRTDVG-----APFGPQGHRDVPFSPDEMVP 447 P GP Q Q G GP GP + G P G +G P P E Sbjct: 217 --------PVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGE 268 Query: 448 PSMNSQSGTIG----PDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVH 503 P N G +G P + LK + + K E V S + Sbjct: 269 PGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGE--VGAPGSKGE--AG 324 Query: 504 QHGPRGVVRGPPPPYQMTPSEGWAPGGTEPFSDGIN----MPHSLPPRGMAPHPNMPGSQ 559 GP G + GP P M G P G + P + P G+ PG+ Sbjct: 325 PTGPMGAM-GPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNP 383 Query: 560 MRLPGFAGMINSE-MEGPN-------VPNPASRPGLSGVSWPDDVPKIPDGRNFPPGQGI 611 + G AG + EGP P P PGL G D P G P G Sbjct: 384 -GMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTP----GAKGPTGSPG 438 Query: 612 FSGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEP 671 SGP P G PPG PG Q P Sbjct: 439 TSGP------PGSAG-----------------PPGS---------------PGPQGSTGP 460 Query: 672 GN---NPIFPRIP-VEGPLSPSRGDFPKGIPPQMGP-GRELEFGMVPSGMKGDVNLNVNM 726 P P +P +G P P GI +GP G E + G P G G V Sbjct: 461 QGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRG--PRGDPGTVGP---- 514 Query: 727 GSNSQMIPQKMREAGAGPEEMLKLRPGGSDMLP----AQQKMVPL----PFGEHPQQEYG 778 P + E GA GSD LP AQ + P+ P G Q + G Sbjct: 515 -------PGPVGERGAPGNRGFP----GSDGLPGPKGAQGERGPVGSSGPKGS--QGDPG 561 Query: 779 MGPRPFLPMSQGPGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNT-APPV 837 P LP ++G N G++ +GP PP + P S+ P Sbjct: 562 RPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKG 621 Query: 838 QRGLGRKPLDISVAG--SQVHSPGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGM 895 G KP + AG Q +PG + P+ V P L G P Sbjct: 622 SSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPS-GPVGPPGLAGERGEQGPP--------- 671 Query: 896 LAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLT 955 GP + PP P P P P P G P P Sbjct: 672 --GPTGFQGLPGPPGPPGEGGKPGDQGVPGDPG-----AVGPLGPRGERGNPGERGEPGI 724 Query: 956 MASPAMLGNVESGGPPPPTASQPASVNIPGSLPSSTPYTMPPEPTLSQNPLSIMMSRMSK 1015 P G GP P S P PG MP E ++ P R Sbjct: 725 TGLPGEKGMAGGHGPDGPKGS-PGPSGTPGDTGPPGLQGMPGERGIAGTP-GPKGDRGGI 782 Query: 1016 FAMPSSTPLYHDAIKTVASSDDDSPPAR------SPNLPSMNNMPGMGINTQNPRISGPN 1069 + +D + + PA P + PG N + +GP Sbjct: 783 GEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPT 842 Query: 1070 PVVPM-----PTLSPMGMTQPLSHSNQ----MPSPNAVGPNIPPHGVPMGPGLMSHNPIM 1120 V P P +P + P P + + PHG PGL Sbjct: 843 GAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKG----- 897 Query: 1121 GHGSQEPPMVPQGRMGFPQGFPPVQSP-PQQVPFPHNGPSG--GQGSFPGGMGFPGE--- 1174 G G+Q PP G GFP V P P P P GP G G+ PG G PG Sbjct: 898 GRGTQGPP----GATGFPGSAGRVGPPGPAGAPGPA-GPLGEPGKEGPPGLRGDPGSHGR 952 Query: 1175 ----GPLGRPSNLPQSSADAALCKPG--GPGGPDSFT----VLGNSMPSVFTDPDLQEVI 1224 GP G P +PG GP GP T ++G MP + + + Sbjct: 953 VGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVG--MPGQRGERGMPGL- 1009 Query: 1225 RPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEV--PGRKQPQG-PGP-------GFSHMQ 1274 PG G P ++ P+ T P G V PG P G PGP G Sbjct: 1010 -PGPAGTP----GKVGPT---GATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRD 1061 Query: 1275 GMMGEQAPRMG---LALPGMGG----PGPVGTPDIPLGTAPSMPGHNPMRPPAFL-QQGM 1326 G +GE+ R LPG G PGPVG P G P+ PP ++G+ Sbjct: 1062 GAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPG-DAGQRGDPGSRGPIGPPGRAGKRGL 1120 Query: 1327 MGPH-------------------HRMMSPAQSTMPGQPTLMSNPAAAVGMIPGKDRGPAG 1367 GP HR + Q +PG P +A P RGP Sbjct: 1121 PGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQG-LPGPPGPNGEQGSAGIPGPFGPRGP-- 1177 Query: 1368 LYTHPGPVGSPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 PGPVG G + G +GP + P G+ VG G PG PG Sbjct: 1178 ----PGPVGPSGKEGN-PGPLGP---------IGPPGVRGSVGEAGPEGPPGEPG 1218 Score = 87.8 bits (216), Expect = 7e-17 Identities = 309/1263 (24%), Positives = 387/1263 (30%), Gaps = 308/1263 (24%) Query: 256 PTPPIPAPAPKPAAPPRPLDRESPGVENK--LIPSVG-SPASSTPLPPDG---------- 302 P PP P P RP + G++ K L VG P S P+ P G Sbjct: 173 PGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGG 232 Query: 303 ---TGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGEPPTLGENPDGLSQEQLEHR 359 TGP P + P G S P+ PP P GEP G Sbjct: 233 AGPTGPPGEPGD----PGPMGPIGSRG-PEGPPGKPGEDGEPGRNGN------------- 274 Query: 360 ERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPGVLDGPQKKPEGPIQAMMAQSQSLGKG 419 P E F G S G + PG P K + + +G Sbjct: 275 ---------------PGEVGFAG--SPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVG-A 316 Query: 420 PGPRTDVGAPFGPQGHRDVPFSPDEMVPPSMNSQSGTIGPDHLDHMTPEQIAWLKLQQEF 479 PG + + G P GP G + + P M + G +GP P Q Sbjct: 317 PGSKGEAG-PTGPMG------AMGPLGPRGMPGERGRLGPQG----APGQRG-------- 357 Query: 480 YEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPPPPYQMTPSEGWAPGGT----EPFS 535 HG G GP P + S G+ PG E Sbjct: 358 ------------------------AHGMPG-KPGPMGPLGIPGSSGF-PGNPGMKGEAGP 391 Query: 536 DGINMPHSLPPRGMAPHPNMPGSQMRLPGFAGMINSEMEGPNVPNPASRPGLSGVSWPDD 595 G P P+G PG + PG G I ++ P P PG SG Sbjct: 392 TGARGPEG--PQGQRGETGPPG-PVGSPGLPGAIGTD-GTPGAKGPTGSPGTSGPPGSAG 447 Query: 596 VPKIPDGRNFPPGQGIFSGPG-------RGER----FPNPQGL-------SEEMFQQQLA 637 P P + QGI PG +GE P P G+ EE + Sbjct: 448 PPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRG 507 Query: 638 EKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIFPRIPVEGPLSPSRGDFPKGI 697 + PPG E P NR PGS P +G P PKG Sbjct: 508 DPGTVGPPGPVGERGAPG---NRGFPGSDGLPGPKG--------AQGERGPVGSSGPKG- 555 Query: 698 PPQMGPGRELEFGMVPSGMKGDVNLNVNMGSNSQMIPQKMREAGAGPEEMLKLRPGGSDM 757 Q PGR E G+ G L N G Q K+ GA P E + P GS Sbjct: 556 -SQGDPGRPGE-----PGLPGARGLTGNPG--VQGPEGKLGPLGA-PGEDGRPGPPGSIG 606 Query: 758 LPAQQKMVPLPFGEHPQQEYGMGPRP------FLPMSQGPGSNSGLRNLREPIGPDQRTN 811 + Q + LP P+ G +P +P +G G P+GP Sbjct: 607 IRGQPGSMGLP---GPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAG 663 Query: 812 SRLSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLDISVAG-----------------SQ 854 R PP P P PP G G KP D V G + Sbjct: 664 ERGEQGPPGPTGFQGLP-----GPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGE 718 Query: 855 VHSPGINPLKSPT----MHQVQSPMLGSPSGNLKSPQT-PSQLAGMLAGPAAAASIKSPP 909 PGI L H P GSP + T P L GM G A P Sbjct: 719 RGEPGITGLPGEKGMAGGHGPDGPK-GSPGPSGTPGDTGPPGLQGM-PGERGIAGTPGPK 776 Query: 910 ----VLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMASPAMLGNV 965 +G A + P P P P G P + P GN Sbjct: 777 GDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRG---LVGPPGSRGNP 833 Query: 966 ESGGPPPPTASQPASVNIPGSLPSSTPYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLY 1025 S G PT G++ + P +P + P P Sbjct: 834 GSRGENGPT----------GAVGFAGPQGPDGQPGVKGEP-----------GEPGQ---- 868 Query: 1026 HDAIKTVASSDDDSPPARSPNLPSMNNMPGM--GINTQNP-----------RISGPNPV- 1071 K A S A SP N +PG+ G TQ P R+ P P Sbjct: 869 ----KGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAG 924 Query: 1072 --VPMPTLSPMGMTQPLSHSNQMPSPNAVGPNIPPHGVPMGPGLMSHNPIMGHGSQEPPM 1129 P L G P S VG P G P GPG G + P Sbjct: 925 APGPAGPLGEPGKEGPPGLRGDPGSHGRVGDR-GPAGPPGGPGDKGDPGEDGQPGPDGPP 983 Query: 1130 VP------QGRMGFP-----QGFPPVQSP---PQQVPFPHNGPSGGQGSF--PGGMGFPG 1173 P +G +G P +G P + P P +V GP+G G PG +G PG Sbjct: 984 GPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKV-----GPTGATGDKGPPGPVGPPG 1038 Query: 1174 -EGPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGATGIP 1232 GP+G P P GP G D ++ D PG+ G P Sbjct: 1039 SNGPVGEPG-------------PEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAP 1085 Query: 1233 EFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPGPGFSHMQGMMGEQAPRMGLALPG-- 1290 P P Q RG+ PG + P GP PG + +G+ G Q PR G Sbjct: 1086 ----GTPGPVGAPGDAGQ---RGD-PGSRGPIGP-PGRAGKRGLPGPQGPRGDKGDHGDR 1136 Query: 1291 --------------MGGPGPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMSP 1336 G PGP G P+ G+A P PP G +GP + +P Sbjct: 1137 GDRGQKGHRGFTGLQGLPGPPG-PNGEQGSAGIPGPFGPRGPP-----GPVGPSGKEGNP 1190 Query: 1337 AQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGLYTHPGPVGSPGMMMSMQG-MMGPQQNIM 1395 G P + + A GP G PGP G PG + + G +MG M Sbjct: 1191 GPLGPIGPPGVRGSVGEA------GPEGPPGEPGPPGPPGPPGHLTAALGDIMGHYDESM 1244 Query: 1396 IPP 1398 P Sbjct: 1245 PDP 1247 Score = 79.3 bits (194), Expect = 2e-14 Identities = 146/549 (26%), Positives = 185/549 (33%), Gaps = 137/549 (24%) Query: 931 PGWTSSPKPPLQSPGIPPNHKAPLTMASP---AMLGNVESGGPPPPTASQPASVN----- 982 PG +P PP P+H P ++ P M G E G P SV Sbjct: 167 PGQPGAPGPPGH-----PSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPR 221 Query: 983 ----IPGSLPSSTPYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDD 1038 + G + P P EP P+ + SR P P +D Sbjct: 222 GPQGLQGQQGGAGPTGPPGEPG-DPGPMGPIGSRG-----PEGPP---------GKPGED 266 Query: 1039 SPPARSPN--------------LPSMNNMPGMGINTQNPRISGPNPVVPMP-------TL 1077 P R+ N P +PG+ + + + GP V P Sbjct: 267 GEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPT 326 Query: 1078 SPMGMTQPLSHSNQMPSPNAVGPNIPP-----HGVPMGPGLMSHNPIMGHGSQEPPMVPQ 1132 PMG PL +GP P HG+P PG M P+ Sbjct: 327 GPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMG------------PLGIP 374 Query: 1133 GRMGFPQGFPPVQSPPQQVPFPHNGPSGGQGSF-----PGGMGFPG-EGPLGRPSNLPQS 1186 G GFP G P ++ + P GP G QG PG +G PG G +G Sbjct: 375 GSSGFP-GNPGMKG--EAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGT---P 428 Query: 1187 SADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVIR--PGATGIPEFDLSRIIPSEK 1244 A PG G P S G+ P T P + IR PG G+P F Sbjct: 429 GAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGP---QGIRGQPGDPGVPGFKG-------- 477 Query: 1245 PSQTLQYFPRGEVPGRKQPQGP-GPGFSHMQGMMGEQAPRMGLALPG-MGGPGPVGTPDI 1302 + P+GE PG QGP GP G G++ PR PG +G PGPVG Sbjct: 478 -----EAGPKGE-PGPHGIQGPIGP-----PGEEGKRGPRGD---PGTVGPPGPVGERGA 523 Query: 1303 PLGTAPSMPGHNPMRPPAFLQQ-----GMMGPHHRMMSPAQSTMPGQPT---LMSNPAAA 1354 P PG + + P Q G GP P + PG P L NP Sbjct: 524 PGNRG--FPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGV- 580 Query: 1355 VGMIPGKDRGPAGLYTHPGPVGSPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGF 1414 +GP G GP+G+PG G GP +I I Q G+ G G Sbjct: 581 --------QGPEGKL---GPLGAPGE----DGRPGPPGSIGIRGQPGSMGLPGPKGSSGD 625 Query: 1415 SQGPGNPGN 1423 PG GN Sbjct: 626 PGKPGEAGN 634 Score = 65.5 bits (158), Expect = 4e-10 Identities = 86/299 (28%), Positives = 106/299 (35%), Gaps = 32/299 (10%) Query: 1143 PVQSPPQQVPFPHNGPSGGQGSFPGGMGFPGEGPLGRPSNLPQSSADAALCKPGGPGGPD 1202 PV P + P P GG +F G +G G P +P + +PG G P Sbjct: 85 PVTPPGECCPVCSQTPGGGNTNFGRGR----KGQKGEPGLVPVVTGIRG--RPGPAGPPG 138 Query: 1203 SFTVLGNSMPSVFTDPDLQEVI--RPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGR 1260 S G P P + I PG G P PS L ++ G Sbjct: 139 SQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGL 198 Query: 1261 KQPQGPGPGFSHMQGMMGEQAPRMGLALPGM-GGPGPVGTPDIPLGTAPSMP--GHNPMR 1317 + G G M G +G PR L G GG GP G P P P P P Sbjct: 199 DEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEG 258 Query: 1318 PPAFLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAAAVGMIPGKD--RGPAGLYTHPGPV 1375 PP + G G R +P + G P P A +PG RG GL G V Sbjct: 259 PPG--KPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPG--LPGLKGHRGHKGLEGPKGEV 314 Query: 1376 GSPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQG----------PGNPGNM 1424 G+PG +G GP + + PRGM + G G QG PG PG M Sbjct: 315 GAPGS----KGEAGPTGPMGAMGPLGPRGMPGERGRLG-PQGAPGQRGAHGMPGKPGPM 368 Score = 40.4 bits (93), Expect = 0.012 Identities = 149/626 (23%), Positives = 192/626 (30%), Gaps = 139/626 (22%) Query: 235 PQQPPAPANQ--DQNSSQNTRLQPTPPIPAPAPKPAAPPRPLDRESPGVENKLIPSVGSP 292 P PP A + +Q T Q P P P P +P D+ PG P Sbjct: 655 PVGPPGLAGERGEQGPPGPTGFQGLPGPPGP---PGEGGKPGDQGVPG----------DP 701 Query: 293 ASSTPLPPDGTGPNSTPNNRAVTPVS----QGSNSSSADPKAPPPPPVSSGEPPTLGENP 348 + PL P G N P R ++ + + P P P SG P G P Sbjct: 702 GAVGPLGPRGERGN--PGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTG--P 757 Query: 349 DGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSG-----GPQQNPGVLDGPQKKPE 403 GL E + + + E T G GP PG +K E Sbjct: 758 PGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGE 817 Query: 404 GPIQAMMAQSQSLGKGPGPRTDVG--------APFGPQGHRDVPFSPDEMVPPSMNSQSG 455 + ++ S G PG R + G P GP G V P E P +G Sbjct: 818 PGPRGLVGPPGSRGN-PGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGE---PGQKGDAG 873 Query: 456 TIGPDHLDHMT----PEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGV- 510 + GP L P + LK R Q V GP G Sbjct: 874 SPGPQGLAGSPGPHGPNGVPGLK-------GGRGTQGPPGATGFPGSAGRVGPPGPAGAP 926 Query: 511 ----------------VRGPPPPYQMTPSEGWA--PGGT----EPFSDGINMPHSLP-PR 547 +RG P + G A PGG +P DG P P P Sbjct: 927 GPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPA 986 Query: 548 GMAPHPNMPGSQMRLPGFAGMINSEMEGPNVPNPASRPGLSGVSWP-----DDVPKIPDG 602 G + G +PG G E P +P PA PG G + P P G Sbjct: 987 GTTGQRGIVG----MPGQRG----ERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPG 1038 Query: 603 RNFPPGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMI 662 N P G+ GP + P G + E+ PG A + Sbjct: 1039 SNGPVGEPGPEGPAGNDGTPGRDG--------AVGERGDRGDPGPA------------GL 1078 Query: 663 PGSQRHMEPGNNPIFPRIPVEGPLSPSRGDFPKGIPPQMGPGRELEFGMV-PSGMKGDVN 721 PGSQ PG PV P + P P PGR + G+ P G +GD Sbjct: 1079 PGSQG--APGTPG-----PVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKG 1131 Query: 722 LNVNMGSNSQMIPQKMREAGAGPEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQQEYGMGP 781 + + G QK G + + P P G + +Q P Sbjct: 1132 DHGDRGDRG----QKGHRGFTGLQGL------------------PGPPGPNGEQGSAGIP 1169 Query: 782 RPFLPMS-QGPGSNSGLRNLREPIGP 806 PF P GP SG P+GP Sbjct: 1170 GPFGPRGPPGPVGPSGKEGNPGPLGP 1195 Score = 38.1 bits (87), Expect = 0.061 Identities = 77/342 (22%), Positives = 106/342 (30%), Gaps = 80/342 (23%) Query: 230 DPKPLPQQPPAPANQDQN-------SSQNTRLQPTPPIPAPAPKPAAPPRPLDRESP--- 279 D +P P PP PA + R P P PA P P + P Sbjct: 974 DGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGP 1033 Query: 280 -GVENKLIPSVGSPASSTPLPPDGT----------------GPNSTPNNRAVT----PV- 317 G P VG P P DGT GP P ++ PV Sbjct: 1034 VGPPGSNGP-VGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVG 1092 Query: 318 SQGSNSSSADP--KAPPPPPVSSGEPPTLGENPDGLSQEQLEHRERSLQTLRDIQRMLFP 375 + G DP + P PP +G+ G P G ++ +H +R + + Sbjct: 1093 APGDAGQRGDPGSRGPIGPPGRAGKRGLPG--PQGPRGDKGDHGDRGDRGQKG------- 1143 Query: 376 DEKEFTGAQS----GGP--QQNPGVLDGP--QKKPEGPIQAMMAQSQSLGKGPGPRTDVG 427 + FTG Q GP +Q + GP + P GP+ GP + Sbjct: 1144 -HRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPV------------GPSGKEGNP 1190 Query: 428 APFGPQGHRDVPFSPDEMVPPSMNSQSGTIGP---------------DHLDHMTPEQIAW 472 P GP G V S E P + G GP H D P+ + Sbjct: 1191 GPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAALGDIMGHYDESMPDPLPE 1250 Query: 473 LKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGP 514 Q ++K + V SL + P G + P Sbjct: 1251 FTEDQAAPDDKNKTDPGVHATLKSLSSQIETMRSPDGSKKHP 1292 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 98.6 bits (244), Expect = 4e-20 Identities = 242/986 (24%), Positives = 330/986 (33%), Gaps = 171/986 (17%) Query: 507 PRGVVRGPPPPYQMTPSEGWAPG-----GTEPFSD------GINMPHSLP---------- 545 P G R PPP +TP+ G G +P ++ G +P S P Sbjct: 29 PPGSPRPPPP---VTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGT 85 Query: 546 -PRGMAPHPNMPGSQMRLPGFAGMINSEMEGPNVPNPASRPGLSG-----VSWPDDVPKI 599 R A P G R P + P + +RPG G +S + V + Sbjct: 86 SSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR- 144 Query: 600 PDGRNFPPGQGIFSGPGRGERFPNPQGLSEEMFQQ-QLAEKQLGLPPGMAMEGIRPSMEM 658 P + +G R P P S M ++ + A ++GLP RP E Sbjct: 145 GKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 204 Query: 659 NRM-IPGSQRHMEPGNNPIFPRIPVEG-------PLSPSRGDFPKGIPPQMGPGRELEFG 710 R + + H +P R P G S S P P + GP Sbjct: 205 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSAR-GTP 263 Query: 711 MVPSGMKGDVNLNVNMGSNSQMIPQKMREAGA-GPEEMLKLR---PGGSDMLPA---QQK 763 P+ + Q+ P + A A GP L P G+ P Sbjct: 264 RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNA 323 Query: 764 MVPLPFGEHPQQEYGMGPRPFLPMSQGPGSNSGLRNLREPIGPDQRTNSRLSHMPP-LPL 822 PLP P P P P S P + L+ L P S PP + Sbjct: 324 ATPLPATLPPSPPLAT-PLPLAPPS--PSAPPSLQTLPSPPATPP------SQAPPSMTT 374 Query: 823 NPSSNPTSLNTAPPVQ-------RGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPM 875 P P SL T PP+Q L P ++++ Q L SPT+ S + Sbjct: 375 PPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQ----ATTSLGSPTLQATHSFL 430 Query: 876 LGSP---SGNLKSPQTPSQLAGMLAGPAAAASI-KSPPVLGSAAASPVHLKSP----SLP 927 SP +L SP P+ A S+ SPP+ S + + L SP L Sbjct: 431 TMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQ 490 Query: 928 APSPGWTSSPKPPL----------QSPGIPPNHKAPLTMASPAMLGNVESGGPPP-PTAS 976 A S + SP+ PL QS PP+ + P + L N+ S PPP TAS Sbjct: 491 ALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTAS 550 Query: 977 QPAS---VNIPGSLPSSTPYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVA 1033 P + + P P+ P PP P + P S A P P A+ + Sbjct: 551 APLTTPHLETP-PCPAPCPLQAPPSPLTTPPP-----ETPSSIATP--PPQAPPALASPP 602 Query: 1034 SSDDDSPPARSPNLPSMNNMPGMGINTQNPRISGPNPVVPMPTLSPMGMTQPLSHS---- 1089 SPP P P + + P + P P LSP+ P + + Sbjct: 603 LQGLPSPPLSPLATPPPQAPPXLAL----PPLQAPPSPPASPPLSPLATPSPQAPNALAV 658 Query: 1090 -------NQMPSPNAVGPNIPPHGVPMGPGL---------MSHNPIMGHGS--QEPPMVP 1131 + PSP P PP P+ P ++ P+ S PPM P Sbjct: 659 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 718 Query: 1132 QGRMGFPQGFPPVQSPPQQVP--FPHNGPSGGQGSFPGGM-----GFPGEGPLGRPSNLP 1184 PQ PP+ +PP QVP P + P + P + P + P P++LP Sbjct: 719 SATPP-PQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLP 777 Query: 1185 QS-------SADAALCKP---GGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGATGIPEF 1234 S A AL P P P SF PS P A + Sbjct: 778 MSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 837 Query: 1235 DLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPGPGFSHMQGMMGEQAPRMGLALPGMGGP 1294 L ++ PS S TLQ ++P PGP S PR+ LAL P Sbjct: 838 PLLQVPPSPPASPTLQ--------APRRPPTPGPDTS-------VSGPRLTLALAPGPPP 882 Query: 1295 GPVGTPDIPLGTAPSMPGH--NPMRPPAFLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPA 1352 P +P L + P + GH + P L+ GP A S P +PA Sbjct: 883 PPSRSPSSTL-SGPDLAGHSSSATSTPEELRGYDSGPEG---GAAASPPPDAELAACHPA 938 Query: 1353 AAVGMIPGKDRGPAGLYTHPGPVGSP 1378 A RGPA G G+P Sbjct: 939 A-------WSRGPAPPLAFRGAPGAP 957 Score = 91.3 bits (225), Expect = 6e-18 Identities = 265/1192 (22%), Positives = 373/1192 (31%), Gaps = 217/1192 (18%) Query: 210 NNKTERSTAPLNTQISALRNDPKPLPQQPPAPANQDQNSSQNTRLQPTPPIPAPAPKP-- 267 +NK +++ A + A R P+ P +P +P PP+ A + Sbjct: 2 DNKRDKAKAGAAARTPAARAPGLLTPRPPGSP-------------RPPPPVTPAALRVLG 48 Query: 268 ---AAPPRPLDRESPGVENKLIPSVGSPASSTPLPPDGTGPNSTPNNRAVTPVSQGSNSS 324 A +PL + G+ IP A T ++ N A P + G Sbjct: 49 AAGAVGRKPLAERAGGIGGATIPESAPRAGPT------RSAGTSSRNPASRPPASGRGER 102 Query: 325 SADPKAPPPPPVSSGEPPTLGENPDGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQ 384 + K P PVSS + P L Q+ L + + R + + + Sbjct: 103 APPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR-----ISAEETVARGKATEAPKRSALS 157 Query: 385 SGGPQQNPGVLDGPQKKPEGPIQAMMAQSQSLGKGPGPRTDVGAPFGPQGHRDVPFSPDE 444 +G + G G P AM +S++ G T+VG P R P + Sbjct: 158 AGARRDTSGPTPGT------PSPAMARRSRAAG------TEVGLPRPAPSARPRPPTEGP 205 Query: 445 MVPPSMNSQSGTIGPDHLDHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQ 504 S S+ T P P L+ R + L Sbjct: 206 RKSVSSASEHSTTEPSPAARRRPSAGGGLQ---------RPASRSLSSSATPLSSPARSG 256 Query: 505 HGPRGVVRGPPPPYQMTPSEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPGSQMRLPG 564 RG R P P Q P A + P PPR A P Sbjct: 257 PSARGTPRAPAHPSQPKPKGLQA----------LRPPQVTPPRKDAA-----------PA 295 Query: 565 FAGMINSEMEGPNVPNPASRPGLSGVSWPDDVPKIPDGRNFPPGQGIFSGPGRGERFPNP 624 + +S + P+ +RP P D P PP + + P Sbjct: 296 LGPLSSSPLATPSPSGTKARPVP-----PPDNAATPLPATLPPSPPLAT----------P 340 Query: 625 QGLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIFPRIPVEG 684 L+ + + L PP PSM M P + P I V Sbjct: 341 LPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPM-------QAPPSLQTIPPIQVPH 393 Query: 685 PLSPSRGDFPKGIPPQMGPGRELEFGMVPSGMK-GDVNLNVNMGSNSQMIPQKMREAGAG 743 L+ P P L + + G L S M P++ + + Sbjct: 394 SLTS---------PSLQAPPSPLALSSLQATTSLGSPTLQATH-SFLTMSPRQTQASLTS 443 Query: 744 PEEMLKLRPGGSDMLPAQQKMVPLPFGEHPQQEYGMGPRPFLPMSQGPGSNSGLRNLREP 803 P P D P Q PL P + + P P+S P + L+ L Sbjct: 444 PSRPASTPP---DSPPLQ---APLSLPASPPLQTSLSPA-VSPLSS-PLTIHPLQALSSL 495 Query: 804 IGPDQRTNSRLSHMPPLPLNPSSNPTSLNT------APPVQRGLGRKPLDISVAGSQVHS 857 + MPPL S P SL T PP++ P + A + + + Sbjct: 496 ASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTT 555 Query: 858 PGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAAS 917 P + P +Q+P SP P+TPS +A P A ++ SPP+ G + Sbjct: 556 PHLETPPCPAPCPLQAPP--SPL-TTPPPETPSSIA--TPPPQAPPALASPPLQGLPSPP 610 Query: 918 PVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMASPAMLGNVESGGPPPPTASQ 977 L +P AP PPLQ+P PP +A+P+ P P A Sbjct: 611 LSPLATPPPQAPPX----LALPPLQAPPSPPASPPLSPLATPS---------PQAPNALA 657 Query: 978 PASVNIPGSLPSSTPYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYH--DAIKTVASS 1035 + P S P S P P P S P+S PS+TP ++ Sbjct: 658 VHLLQAPFSPPPSPPVQAPFSPPASP-PVS-----------PSATPPSQAPPSLAAPPLQ 705 Query: 1036 DDDSPPARSPNLPSMNNMPGMGINTQNPRISGPNPVVPMPTLSPMGMTQPLSHSNQMPSP 1095 SPPA P PS + P P P P +P P ++ SP Sbjct: 706 VPPSPPASPPMSPS----------------ATPPPQAPPPLAAPPLQVPPSPPASPPMSP 749 Query: 1096 NAVGPNIPPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPH 1155 +A P P P L++ P+ Q PP P P PP Q+PP P Sbjct: 750 SATPP-------PRVPPLLAAPPL-----QVPPSPPASLPMSPLAKPPPQAPPALATPPL 797 Query: 1156 NGPSGGQGSFPGGMGFPGEGPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVF 1215 S FPG+ P ++LP S L P P L PS Sbjct: 798 QALPSPPAS------FPGQAPFSPSASLPMS----PLATPPPQAPPVLAAPLLQVPPSPP 847 Query: 1216 TDPDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQG--PGPGFS-H 1272 P LQ RP G P+ +S P TL P P + P GP + H Sbjct: 848 ASPTLQAPRRPPTPG-PDTSVS------GPRLTLALAPGPPPPPSRSPSSTLSGPDLAGH 900 Query: 1273 MQGMMGEQAPRMGLALPGMGGPGPVGTPDIPLGTA-PSMPGHNPMRPPAFLQQGMMGPHH 1331 G GG PD L P+ P P AF +G G Sbjct: 901 SSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAF--RGAPG--- 955 Query: 1332 RMMSPAQSTMPGQPTLMSNPAAAVGMIP-GKDRGPAGLYTHPG---PVGSPG 1379 + +P P + P +A G+ + GP PG P SPG Sbjct: 956 -------APLPWPPA--TGPGSADGLCTIYETEGPESATPAPGALDPGPSPG 998 Score = 85.1 bits (209), Expect = 4e-16 Identities = 230/1027 (22%), Positives = 331/1027 (32%), Gaps = 235/1027 (22%) Query: 13 SGNTQSSPKSKQEVMVRPPTVMSPSGNPQLDSKFSNQGKQGGSASQSQPSPCDSKSGGHT 72 +G T+S+ S + RPP S +G++ A + P P S G + Sbjct: 77 AGPTRSAGTSSRNPASRPPA--------------SGRGERAPPAKNTSPGPVSSP-GRAS 121 Query: 73 PKALPGPGGSMGLKNGAGNG-AKGKGKRERSISADSFDQR------DPGTPNDDSDIKEC 125 PGP G GL+ A A+GK SA S R PGTP+ + Sbjct: 122 GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR 181 Query: 126 NSADHIKSQDSQHTPHSMTPSNATAPRSSTPSHGQTTATEPTPAQKTPAKVVYVFSTEMA 185 + + + P+ PR S S + + TEP+PA + + Sbjct: 182 AAGTEVGLPRPAPSARPRPPTEG--PRKSVSSASEHSTTEPSPAARRRPS-----AGGGL 234 Query: 186 NKAAEAVLKGQVETIVSFHIQNISNNKTERSTA----PLNTQISALRNDPKPLPQQPPAP 241 + A L + S S T R+ A P + ALR P++ AP Sbjct: 235 QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAP 294 Query: 242 ANQDQNSS-------QNTRLQPTPP-----IPAPAPKPAAPP--RPLDRESPGVENKLIP 287 A +SS T+ +P PP P PA P +PP PL P P Sbjct: 295 ALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPS------P 348 Query: 288 SVGSPASSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVS---SGEPPTL 344 S + P PP T P+ P + P+ A P PP+ S P+L Sbjct: 349 SAPPSLQTLPSPP-ATPPSQAPPSMTTPPMQ-------APPSLQTIPPIQVPHSLTSPSL 400 Query: 345 GENPDGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPGVLDGPQKKPEG 404 P L +L +L+ + P + + P+Q L P + Sbjct: 401 QAPPSPL----------ALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPAST 450 Query: 405 PIQAMMAQSQ-SLGKGPGPRTDVGAPFGPQGHRDVPFSPDEMVPPSMNSQSGTIGPDHLD 463 P + Q+ SL P +T + P SP + P S + P Sbjct: 451 PPDSPPLQAPLSLPASPPLQTSLSPAVSPLS------SPLTIHPLQALSSLASHSP---- 500 Query: 464 HMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPPPPYQMTPS 523 + +++ Q + PP + PS Sbjct: 501 --------------------QAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPS 540 Query: 524 EGWAPGGTEPFSDGINMPHSLPPRGMAPHP-NMPGSQMRLPGFAGMINSEMEGPNVPNPA 582 AP + S + PH P AP P P S + P P P+ Sbjct: 541 --LAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTP-----------PPETPSSI 587 Query: 583 SRPGLSGVSWPDDVPKIPDGRNFPPGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQLG 642 + P P+ P PP QG+ S P P PQ A L Sbjct: 588 ATP----------PPQAPPALASPPLQGLPSPPLSPLATPPPQ-----------APPXLA 626 Query: 643 LPPGMAMEGIRPSMEMNRMIPGSQR-------HMEPGNNPIFPRIPVEGPLSP--SRGDF 693 LPP A S ++ + S + H+ P PV+ P SP S Sbjct: 627 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 686 Query: 694 PKGIPPQMGPGRELEFGMVPSGMKGDVNLNVNMGSNSQMIPQKMREAGAGPEEMLKLRPG 753 P PP P PS A P ++ P Sbjct: 687 PSATPPSQAP---------PS-------------------------LAAPPLQVPPSPPA 712 Query: 754 GSDMLPA--QQKMVPLPFGEHPQQEYGMGPRPFLPMSQGPGSNSGLRNLREPIGPDQRTN 811 M P+ P P P Q P P + P S S R P Sbjct: 713 SPPMSPSATPPPQAPPPLAAPPLQV------PPSPPASPPMSPSATPPPRVP-------- 758 Query: 812 SRLSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQV 871 L PPL + P S P SL +P L + P A L +P + + Sbjct: 759 -PLLAAPPLQV-PPSPPASLPMSP-----LAKPPPQAPPA-----------LATPPLQAL 800 Query: 872 QSPMLGSPSGNLKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSP 931 SP P ++P +PS A + P A ++PPVL A+P+ PS PA Sbjct: 801 PSPPASFPG---QAPFSPS--ASLPMSPLATPPPQAPPVL----AAPLLQVPPSPPA--- 848 Query: 932 GWTSSPKPPLQSPGIPPNHKAPLTMASPAMLGNVESGGPPPPTASQPASVNIPGSLPSST 991 P LQ+P PP +++ P + + G PPPP+ S ++++ P S+ Sbjct: 849 ------SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 902 Query: 992 PYTMPPE 998 T PE Sbjct: 903 SATSTPE 909 Score = 68.6 bits (166), Expect = 4e-11 Identities = 149/660 (22%), Positives = 213/660 (32%), Gaps = 101/660 (15%) Query: 819 PLPLNPSSNPTSLNTAPPVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGS 878 P P PS + A + GL R ++ P P KS + S S Sbjct: 167 PTPGTPSPAMARRSRAAGTEVGLPRP-----APSARPRPPTEGPRKSVSSASEHSTTEPS 221 Query: 879 PSGNLKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPA----PSPGWT 934 P+ + PS G+ + + S + P+ A + P +P PA P P Sbjct: 222 PAARRR----PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGL 277 Query: 935 SSPKPPL-------QSPGIPPNHKAPLTMASPAMLGNVESGGPPPPTASQPASVNIPGSL 987 + +PP +P + P +PL SP+ G PPP A+ P +P S Sbjct: 278 QALRPPQVTPPRKDAAPALGPLSSSPLATPSPS--GTKARPVPPPDNAATPLPATLPPSP 335 Query: 988 PSSTPYTM-PPEPTL---------------SQNPLSI----MMSRMSKFAMP-------- 1019 P +TP + PP P+ SQ P S+ M + S +P Sbjct: 336 PLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSL 395 Query: 1020 SSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMGINTQNPRISGPNPVVPMPTLSP 1079 +S L SS + SP L + ++ M ++ P+ P SP Sbjct: 396 TSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSP 455 Query: 1080 MGMTQPLSHSNQMPSPNAVGPNIPPHGVPMG-------PGLMSHNPIMGHGSQ-EPPMVP 1131 + PLS P ++ P + P P+ L SH+P S PP+ Sbjct: 456 -PLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLET 514 Query: 1132 QGRMGFPQGFPPVQSPPQQVPFPHNGPSGGQGSFPGGMGFPGEGPLGRPS-NLPQSSADA 1190 Q + P +Q+PP + P P S PL P P A Sbjct: 515 QSSLAPPS----LQTPPASLTTP---PLENLPSLAPPPLQTASAPLTTPHLETPPCPAPC 567 Query: 1191 ALCKPGG------PGGPDSFTVLGNSMPSVFTDPDLQEV----IRPGATGIPEFDLSRII 1240 L P P P S P P LQ + + P AT P+ + Sbjct: 568 PLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLAL 627 Query: 1241 PSEKPSQTLQYFPRGEVPGRKQPQGPGPGFSHMQGMMGEQAPRMGLALPGMGGP--GPVG 1298 P + + P PQ P H+ QAP P + P P Sbjct: 628 PPLQAPPSPPASPPLSPLATPSPQAPNALAVHLL-----QAPFSPPPSPPVQAPFSPPAS 682 Query: 1299 TPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAAAVGMI 1358 P P T PS + PP LQ P MSP+ + P P ++ P Sbjct: 683 PPVSPSATPPSQAPPSLAAPP--LQVPPSPPASPPMSPSATPPPQAPPPLAAPP------ 734 Query: 1359 PGKDRGPAGLYTHPGPVGSPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGP 1418 L P P SP M S + PP P A + M ++ P Sbjct: 735 ---------LQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP 785 >gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] Length = 680 Score = 93.6 bits (231), Expect = 1e-18 Identities = 142/510 (27%), Positives = 172/510 (33%), Gaps = 91/510 (17%) Query: 940 PLQSPGIPPNHKA----PLTMASPAMLGNVESGGPPPPTASQPASVNIPGSLPSSTPYTM 995 P G PN K P T+ S + E G P PP + P P P Y Sbjct: 28 PTGIKGPLPNTKTQFFIPYTIKSKGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGS 87 Query: 996 P---PEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNN 1052 P EP L P + + +P P R P P + Sbjct: 88 PGLQGEPGLPGPPGPSAVGKPGVPGLPG------------------KPGERGPYGPKGDV 129 Query: 1053 MPGMGINTQNPRISGPNPVVPMPTLSPMGMTQPLSHSNQMPSPNAVGPNIPP--HGVPMG 1110 P PR P +P P G++ P Q P+ A GP P G P Sbjct: 130 GPA---GLPGPRGPPGPPGIP----GPAGISVPGKPGQQGPT-GAPGPRGFPGEKGAPGV 181 Query: 1111 PGLMSHNPIMGHGSQEPPMVPQGRMGF--PQGFPPVQSPPQQVPFPHNGPSGGQGSFPGG 1168 PG+ MG+G+ P G G PQG PP NG GQ G Sbjct: 182 PGMNGQKGEMGYGAPGRP----GERGLPGPQGPTGPSGPPGVGKRGENGVP-GQPGIKGD 236 Query: 1169 MGFPGE-GPLG--RPSNLPQSSADAALCKPGGPGGPDSFTVLGN----SMPSVFTDPDLQ 1221 GFPGE GP+G P P + KPG G P + G P + P Sbjct: 237 RGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPP 296 Query: 1222 EVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPG-----PGFSHMQGM 1276 +PG +P K + P G PG K QGP PG + G Sbjct: 297 GFGKPG------------LPGLKGERGPAGLPGG--PGAKGEQGPAGLPGKPGLTGPPGN 342 Query: 1277 MGEQAPRMGLALPGMGG-PGPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMS 1335 MG Q P+ +PG G PGP G T P+ P P G G S Sbjct: 343 MGPQGPK---GIPGSHGLPGPKGE------TGPAGPAGYP---------GAKGERGSPGS 384 Query: 1336 PAQSTMPGQPTLMSNPAAAVGMI-PGKDRGPAGLYTHPGPVGSPGM--MMSMQGMMGPQQ 1392 + PG+P L P G+ P D G G PGPVG G M G GP+ Sbjct: 385 DGKPGYPGKPGL-DGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRG 443 Query: 1393 NIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 IP P G G G PG+PG Sbjct: 444 APGIPGTRGPIGPPGIPGFPGSKGDPGSPG 473 Score = 87.4 bits (215), Expect = 9e-17 Identities = 142/530 (26%), Positives = 178/530 (33%), Gaps = 109/530 (20%) Query: 897 AGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIP--PNHKAPL 954 AGP PP SP P LP P PG ++ KP + PG+P P + P Sbjct: 68 AGPRGHPGPSGPPGK-PGYGSPGLQGEPGLPGP-PGPSAVGKPGV--PGLPGKPGERGPY 123 Query: 955 TM---ASPAMLGNVESGGPPPPTASQPASVNIPGSLPSSTPYTMPPEPTL---SQNPLSI 1008 PA L G P PP PA +++PG P T P P + + Sbjct: 124 GPKGDVGPAGLPGPR-GPPGPPGIPGPAGISVPGK-PGQQGPTGAPGPRGFPGEKGAPGV 181 Query: 1009 MMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSM--NNMPGM-------GIN 1059 K M P + + + P+ P + N +PG G Sbjct: 182 PGMNGQKGEMGYGAP-GRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFP 240 Query: 1060 TQNPRISGPNPVVPMPTLSPMGMTQP----------LSHSNQMP-SPNAVGPNIPP-HGV 1107 + I P P P P G+ +P + + +P +P GP PP G Sbjct: 241 GEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGK 300 Query: 1108 PMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHNGPSGGQGSFPG 1167 P PGL G QG G P G P + PP + GP G +G PG Sbjct: 301 PGLPGLKGERGPAGLPGGPGAKGEQGPAGLP-GKPGLTGPPGNM-----GPQGPKG-IPG 353 Query: 1168 GMGFPGE-------GPLGRPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDL 1220 G PG GP G P + + + KPG PG P GN P L Sbjct: 354 SHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGN--------PGL 405 Query: 1221 QEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQGPGPGFSHMQGMMGEQ 1280 PG G P G PG P GP G M G GE Sbjct: 406 -----PGPKGDPGV--------------------GGPPGLPGPVGPA-GAKGMPGHNGEA 439 Query: 1281 APRMGLALPGMGGP-GPVGTPDIPLGTA-PSMPGHNPMRPPAFLQQGMMGPHHRMMSPAQ 1338 PR +PG GP GP G P P P PG P P +G+ GP Sbjct: 440 GPRGAPGIPGTRGPIGPPGIPGFPGSKGDPGSPG--PPGPAGIATKGLNGP--------- 488 Query: 1339 STMPGQPTLMSNPAAAVGMIPGKDRGPAGLYTHPGPVGSPGMMMSMQGMM 1388 + PG P P G GL PGP G PG + +G + Sbjct: 489 TGPPGPPG------------PRGHSGEPGLPGPPGPPGPPGQAVMPEGFI 526 Score = 85.9 bits (211), Expect = 3e-16 Identities = 149/527 (28%), Positives = 189/527 (35%), Gaps = 102/527 (19%) Query: 932 GWTSSPKPPLQSPGIPPNHKAPLT------MASPAMLGNVESGGPPPPTA-SQPASVNIP 984 G +P PP P P H P SP + G GPP P+A +P +P Sbjct: 57 GEQGTPGPP--GPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLP 114 Query: 985 GSLPSSTPYTMPPEPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARS 1044 G PY P P + R P + A +V P + Sbjct: 115 GKPGERGPYG----PKGDVGPAGLPGPR----GPPGPPGIPGPAGISVPGKPGQQGPTGA 166 Query: 1045 PN---LPSMNNMPGM-GINTQNPRISGPNPVVP----MPTLSPMGMTQPLSHSNQMPSPN 1096 P P PG+ G+N Q + P P +P P G T P P Sbjct: 167 PGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLP--GPQGPTGP-------SGPP 217 Query: 1097 AVGPNIPPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPFPHN 1156 VG +GVP PG+ G + P+ P G PQG PP + P+ + P Sbjct: 218 GVGKR-GENGVPGQPGIKGDR---GFPGEMGPIGPPG----PQG-PPGERGPEGIGKPGA 268 Query: 1157 GPSGGQGSFPGGMGFPG----EGPLGRPS----NLPQSSADAALC-KPGGPGGPDSFTVL 1207 + GQ PG G PG GP G P LP + PGGPG Sbjct: 269 AGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPA 328 Query: 1208 GNSMPSVFTDPDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPGRKQPQG-P 1266 G T P + G GIP S +P K +T P G PG K +G P Sbjct: 329 GLPGKPGLTGPP-GNMGPQGPKGIPG---SHGLPGPK-GETGPAGPAG-YPGAKGERGSP 382 Query: 1267 G----PGFSHMQGMMGEQAPRMGLALPG-MGGPGPVGTPDIPLGTAPS----MPGHNPMR 1317 G PG+ G+ G P+ LPG G PG G P +P P+ MPGHN Sbjct: 383 GSDGKPGYPGKPGLDG---PKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEA 439 Query: 1318 PPAFLQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGLYTH--PGPV 1375 P G+ G + P +PG P +P + PG GPAG+ T GP Sbjct: 440 GPRG-APGIPGTRGPIGPPG---IPGFPGSKGDPGS-----PGPP-GPAGIATKGLNGPT 489 Query: 1376 GSPGMMMSMQGMMGPQQNIMIPPQMRPRGMAADVGMGGFSQGPGNPG 1422 G PG PP PRG + + G+ G PG PG Sbjct: 490 GPPG-----------------PP--GPRGHSGEPGLPGPPGPPGPPG 517 Score = 57.4 bits (137), Expect = 1e-07 Identities = 124/457 (27%), Positives = 157/457 (34%), Gaps = 117/457 (25%) Query: 505 HGPRGVV--------RGPPPPYQMTPSEGWAPGGTEPFSDGINMPHSLP-PRGMAPHPNM 555 +GP+G V RGPP P P G + P G P P PRG Sbjct: 123 YGPKGDVGPAGLPGPRGPPGP----PGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGA 178 Query: 556 PGSQMRLPGFAGMINSEMEG-PNVPNPASRPGLSGVSWPDDVPK--------------IP 600 PG +PG G G P P PG G + P P I Sbjct: 179 PG----VPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIK 234 Query: 601 DGRNFPPGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNR 660 R FP G PG PQG E + + + PG A +P + + Sbjct: 235 GDRGFPGEMGPIGPPG-------PQGPPGERGPEGIGK------PGAAGAPGQPGIPGTK 281 Query: 661 MIPGSQRHMEPGNNPIFPRIPVEGPLSPSRGDFPKGIPPQMGPGRELEFGMVPSGMKGDV 720 +PG+ P P F + + G L RG P G+P GPG + E G P+G+ G Sbjct: 282 GLPGAPGIAGPPGPPGFGKPGLPG-LKGERG--PAGLPG--GPGAKGEQG--PAGLPGKP 334 Query: 721 NLN---VNMG-------SNSQMIPQKMREAG-AGPEEMLKLRPG--------GSDMLPAQ 761 L NMG S +P E G AGP PG GSD P Sbjct: 335 GLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGY----PGAKGERGSPGSDGKPGY 390 Query: 762 QKMVPL------PFGEHPQQEYGMGPRPFLPMSQG-------PGSNS--------GLRNL 800 L P P+ + G+G P LP G PG N G+ Sbjct: 391 PGKPGLDGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGT 450 Query: 801 REPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLDISVA-----GSQV 855 R PIGP P +P P S + PP G+ K L+ G + Sbjct: 451 RGPIGP-----------PGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRG 499 Query: 856 HS--PGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPS 890 HS PG+ P Q+ M P G +K+ Q PS Sbjct: 500 HSGEPGLPGPPGPPGPPGQAVM---PEGFIKAGQRPS 533 Score = 49.3 bits (116), Expect = 3e-05 Identities = 118/505 (23%), Positives = 163/505 (32%), Gaps = 117/505 (23%) Query: 255 QPTPPIPAPA-----PKPAAPPRPLDRESPGVENKLIPSV-GSPASSTPLPPDGTGPNST 308 Q TP P PA P P+ PP SPG++ + P + G P S P G Sbjct: 59 QGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGE--PGLPGPPGPSAVGKPGVPGLPGK 116 Query: 309 PNNRA-VTPVSQGSNSSSADPKAPPPPPVSSGEPPTLGENPDGLSQEQLEHRERSLQTLR 367 P R P + P+ PP PP G P G + G +Q Sbjct: 117 PGERGPYGPKGDVGPAGLPGPRGPPGPP---GIPGPAGISVPGKPGQQ------------ 161 Query: 368 DIQRMLFPDEKEFTGAQSGGPQQNPGVLDGPQKKPEGPIQAMMAQSQSLGKG-PGPRTDV 426 GP PG P +K + M Q +G G PG + Sbjct: 162 -------------------GPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGER 202 Query: 427 GAPFGPQGHRDVPFSPDEMVPPSMNSQSGTIGPDHL--DHMTPEQIAWLKLQQEFYEEKR 484 G P GPQG P P ++G G + D P ++ + Sbjct: 203 GLP-GPQG----PTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPPGE 257 Query: 485 RKQEQVVVQQCSLQDMMVHQHGPRGV-----VRGPPPPYQMTPSEGWAPGGTEPFSDGIN 539 R E + + G +G+ + GPP P PG +P G+ Sbjct: 258 RGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGP----------PGFGKPGLPGLK 307 Query: 540 MPHSLPPRGMAPHPNMPGSQ--MRLPGFAGMI----NSEMEGP-NVPNPASRPGLSGVSW 592 P G+ P G Q LPG G+ N +GP +P PG G + Sbjct: 308 GERG--PAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETG 365 Query: 593 PDDVPKIP-----------DGRNFPPGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQL 641 P P DG+ PG+ GP P P+G + + Sbjct: 366 PAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKG-----------DPGV 414 Query: 642 GLPPGMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIFPRIPVEGPLSP--------SRGDF 693 G PPG+ + P+ + +PG P P P GP+ P S+GD Sbjct: 415 GGPPGLP-GPVGPAGA--KGMPGHNGEAGPRGAPGIP--GTRGPIGPPGIPGFPGSKGD- 468 Query: 694 PKGIPPQMGPGRELEFGMVPSGMKG 718 G P GP G+ G+ G Sbjct: 469 -PGSPGPPGPA-----GIATKGLNG 487 Score = 34.7 bits (78), Expect = 0.67 Identities = 72/297 (24%), Positives = 92/297 (30%), Gaps = 80/297 (26%) Query: 231 PKPLPQQPPAPANQDQNSSQNTRLQPTPPIPA----PAPK----PAAPPRPLDRESPGVE 282 P+ P + AP N + P P P P+ P+ PP R GV Sbjct: 169 PRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVP 228 Query: 283 NKLIPSV----GSPASSTPLPPDGTGPNSTPNNR----------AVTPVSQGSNSSSADP 328 + P + G P P+ P G P P R A P G + P Sbjct: 229 GQ--PGIKGDRGFPGEMGPIGPPG--PQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLP 284 Query: 329 KAP----PPPPVSSGEPPTLG----ENPDGLSQEQLEHRERSLQTLRDIQRMLFPDEKEF 380 AP PP P G+P G P GL E+ L P + Sbjct: 285 GAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGL--------PGKPGL 336 Query: 381 TGAQSG-GPQQNPGV-----LDGPQKK--PEGPIQAMMAQSQSLGKG------------- 419 TG GPQ G+ L GP+ + P GP A+ + G Sbjct: 337 TGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGL 396 Query: 420 ---------PGPRTDVGA--------PFGPQGHRDVPFSPDEMVPPSMNSQSGTIGP 459 PGP+ D G P GP G + +P E P GT GP Sbjct: 397 DGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGP 453 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 90.9 bits (224), Expect = 8e-18 Identities = 173/691 (25%), Positives = 242/691 (35%), Gaps = 131/691 (18%) Query: 818 PPLPLNPSSNPTSLNTAPPVQRGLGRKPLDISVAGSQ-----VHSPGI-NPLKSPTMHQV 871 P P+ S+P S PV+ + +S GS+ HSP +P +PT V Sbjct: 817 PDTPIGNLSSPVS-----PVEASFLPEN-SLSFQGSKDSPATTHSPTPPSPKGAPTPSAV 870 Query: 872 QSPMLGSPSGNLKSPQ---TPS--QLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSL 926 +P+ SP G P+ TPS L GPA A K P L ++SP K+ + Sbjct: 871 -TPL--SPKGVTLPPKETPTPSVVNLPFPKEGPATPAP-KQAPALSMTSSSP--KKARAT 924 Query: 927 PAP-----SPGWTSSPKPPLQSPGIP------PNHK---APLTMASPAMLGNVES----G 968 PAP SP +P PP +P P P+ K P P+ G + G Sbjct: 925 PAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKG 984 Query: 969 GPPPPTASQPASVNIPGSLPS-----STPYTMPPEPTLSQNPLSI--------MMSRMSK 1015 P PP A+ P+ P + PS + P PP P S + S Sbjct: 985 APTPPAATPPSPKGGPAT-PSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSP 1043 Query: 1016 FAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMGINTQNPRISGPNPVVPMP 1075 P++TPL A T A++ P P PS+ P P + P+P Sbjct: 1044 KGSPAATPLPKGAPTTPAATLPS--PKGGPATPSLKGAP------TPPAATPPSPKGGPA 1095 Query: 1076 TLSPMGMTQPLSHSNQMPSPNAVGPNIPPH-GVPMGPGLMSHNPIMGHGSQEP------- 1127 T SP G P+ + PSP G PPH G P P +P G + P Sbjct: 1096 TPSPKG--APMPPAATPPSPKG-GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTP 1152 Query: 1128 ---PMVPQGRMGF--PQGFP--PVQSPPQ-----QVPFPHNGPSGGQGSFP---GGMGFP 1172 P P+G + P+G P P +PP P P P+ + P GG+ P Sbjct: 1153 AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP 1212 Query: 1173 G---------------EGPLGRPSNLPQSSADAALCKPGGP-GGPDSFTVLGNSMPSVFT 1216 +G L PS P+ + P P GGP + G P T Sbjct: 1213 SPKGAPTTPAATPPSPKGGLATPS--PKGAPTTPAATPPSPKGGPATPPPKGAPTPPAAT 1270 Query: 1217 DPDLQ-EVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRG---EVPGRKQPQGPGPGFSH 1272 P L+ + P G P P+ P+G P + P P Sbjct: 1271 PPSLKGGLATPPHKGAP-----------NPAVVTPPSPKGGPATSPPKGAPTPPAATPPS 1319 Query: 1273 MQGMMGEQAPRMGLALPGMGGPGPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHR 1332 +G G P+ P + P P GTP +P T PS G P P GP Sbjct: 1320 PKGSPGTPPPKGAPTPPAVTPPSPKGTPTLP-ATTPSSKG-GPTTP-----SSKEGPTPP 1372 Query: 1333 MMSPAQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGLYTHPGPVGSPGMMMSMQGMMGPQQ 1392 +P+ P A+ G PA + P +P ++ +G P + Sbjct: 1373 AATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPL--SPKKAPATPVTREGAATPSK 1430 Query: 1393 NIMIPPQMRPRGMAADVGMGGFSQGPGNPGN 1423 + PP + P + GP P + Sbjct: 1431 GDLTPPAVTPVSLKKAPATSAPKGGPATPSS 1461 Score = 90.1 bits (222), Expect = 1e-17 Identities = 304/1320 (23%), Positives = 411/1320 (31%), Gaps = 299/1320 (22%) Query: 165 EPTPAQKTPAKVVYVFSTEMANKAAEAVLKGQVETIVSFHIQNISNNKTERSTAPLNTQI 224 +P + P+ V+ F T+ + A L+G AP + Sbjct: 511 DPEDLKNLPSSVLVKFPTQKDLQTVPASLEG----------------------APFSPAQ 548 Query: 225 SAL--RNDPKPLPQQPPAPANQDQNSSQNTRLQ-PTPPIPAPAPKPAAPPRPLDRESPGV 281 + L + DP LP AP N S ++ + P P A K P P+ + + + Sbjct: 549 AGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSM 608 Query: 282 ENKLIPSVGSPAS----STPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVS 337 + L V S AS + PD GP + +TP SADP P Sbjct: 609 TSPL--GVNSSASVIKTDSYAGPDSAGP--LLKSSLITPTVAAFPLESADPAGVAPTTAK 664 Query: 338 SGEPPTLGENPD-----GLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNP 392 T +P L+ + +E +L TL L P E + PQ Sbjct: 665 GTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLP-----LVPTASENCPV-APSPQNTC 718 Query: 393 GVLDGPQKKPEGPIQAMMAQSQSLGKGPG-----------------------PRTDVGAP 429 L PE P G PG P D GA Sbjct: 719 APLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGAS 778 Query: 430 FGPQGHRDVPFSPDEMVPPSMN---------SQSGTIGPDHLDHMTPEQIAWLKLQQEFY 480 + + D P ++ ++ G+ GPD TP I L Sbjct: 779 ATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPD-----TP--IGNLSSPVSPV 831 Query: 481 EEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPPPPYQMTPSEGWAPGGTEPFSDGINM 540 E + + Q H P +G P P +TP +P G Sbjct: 832 EASFLPENSLSFQGSKDSPATTHSPTPPSP-KGAPTPSAVTPL---SPKGV--------- 878 Query: 541 PHSLPPRGMAPHPNMPGSQMRLPGFAGMINSEMEGPNVPNPASRPGLSGVSWPDDVPKIP 600 +LPP+ P P++ + LP EGP P P P LS S Sbjct: 879 --TLPPKE-TPTPSV----VNLP-------FPKEGPATPAPKQAPALSMTS--------- 915 Query: 601 DGRNFPPGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQLGLPPGMAMEGIRPSMEMNR 660 S P + P P+G+ + PP PS + Sbjct: 916 ------------SSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP 963 Query: 661 MIPGSQRHMEPGNNPIFPRIPVEGPLSPSRGDFPKGIP---------PQMGP------GR 705 P + P P GP +PS PKG P P+ GP G Sbjct: 964 TPPAAT-----------PPSPKGGPATPS----PKGAPTPPAATPPSPKGGPATPSPKGA 1008 Query: 706 ELEFGMVPSGMKGDVNLNVNMGSNSQMIPQKMREAGAGPEEMLKLRPGGSDMLPAQQKMV 765 + P KG + P + G L P G+ PA + Sbjct: 1009 PTPPAVTPPSPKGS-PAATPFPKGASTPPAATPPSPKGSPAATPL-PKGAPTTPA--ATL 1064 Query: 766 PLPFGEHPQQEYGMGPRPFLPMSQGPGSNSGLRNLREPIGPDQRTNSRLSHMPPLPLNPS 825 P P G P P P + P G P P + + MPP PS Sbjct: 1065 PSPKGGPATPSLKGAPTP--PAATPPSPKGG------PATPSPKG----APMPPAATPPS 1112 Query: 826 SNPTSLNTAPPVQRGLGRKPLDI--SVAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGNL 883 A P +G P S G P P +PT P SP G L Sbjct: 1113 PKG---GLATPPHKGAPTTPAATPPSPKGGLATPP---PKGAPTTPAATPP---SPKGGL 1163 Query: 884 KSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSP----GWTSSPKP 939 +P G PAA +PP A+P +P+ PA +P G ++P P Sbjct: 1164 ATPPP----KGAPTTPAA-----TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSP 1214 Query: 940 ---PLQSPGIPPNHKAPLTMASPAMLGNVESGGPPPPTASQPASVNIPGSLPSSTPYTMP 996 P PP+ K L SP G P P A+ P+ P P T P Sbjct: 1215 KGAPTTPAATPPSPKGGLATPSP-------KGAPTTPAATPPS--------PKGGPATPP 1259 Query: 997 PE--PTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVAS---SDDDSPPARSPNLPSMN 1051 P+ PT P + S A P + A+ T S SPP +P P+ Sbjct: 1260 PKGAPT---PPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAAT 1316 Query: 1052 NMPGMGINTQNPRISGPNPVVPMPTLSPMG-----MTQPLSHSNQMPSPNAVGPNIPPHG 1106 G P P P P SP G T P S + GP PP Sbjct: 1317 PPSPKGSPGTPPPKGAPTPPAVTPP-SPKGTPTLPATTPSSKGGPTTPSSKEGPT-PPAA 1374 Query: 1107 VPM---GPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQSPPQQVPF-PHNGPSGGQ 1162 P GP + +P G P +P P+G P + P +P P P+ Sbjct: 1375 TPSHKGGPAMTPPSPKRG------PAIPS-----PKGDP---TSPAVIPLSPKKAPA--T 1418 Query: 1163 GSFPGGMGFPGEGPLGRPSNLPQS--SADAALCKPGGPGGPDSF---TVLGNSMPSVFTD 1217 G P +G L P+ P S A A GGP P S T+ + PS Sbjct: 1419 PVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEP 1478 Query: 1218 PDLQEV----------IRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVP----GRKQP 1263 P ++V P G P L +IPS EVP R+ P Sbjct: 1479 PAPKQVATSSSPKKAPATPAPMGAP--TLPAVIPSSPK----------EVPATPSSRRDP 1526 Query: 1264 QGPGPGFSHMQGMMGEQAPRMGLALPGMGGPGPVGTPDIPL-GTAPSMP-GHNPMRPPAF 1321 P + AP+ L P M P P TP IP AP+ P PPA Sbjct: 1527 IAPTATLLSKK-TPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAV 1585 Query: 1322 ---LQQGMMGPHHRMMSPAQSTMPGQPTLMSNPAAAVGMIPGKDRGPAGLYTHPGPVGSP 1378 +G P ++ PA ++ P+ P P ++GPA P P G+P Sbjct: 1586 TPSTYKGAPSPKELLIPPAVTS----PSPKEAPTPPAVTPPSPEKGPA----TPAPKGTP 1637 Score = 88.6 bits (218), Expect = 4e-17 Identities = 248/1176 (21%), Positives = 357/1176 (30%), Gaps = 216/1176 (18%) Query: 240 APANQDQNSSQNTRLQPTPPIPAPAPKPAAPPRPLDRESPGVENKLIPSVGSPASSTPLP 299 AP N T L P +P + P P + +P L P + S LP Sbjct: 684 APKNHPVKEGTLTTL---PLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLP 740 Query: 300 PDGTGPNSTP-----NNRAVTPVSQGSNSSSADPKAPPPPPVSSGEPPTLGENPDGLSQE 354 P GT P + + A+ PV+ + S G L ++P L Sbjct: 741 PAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVS 800 Query: 355 QLEHRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPGVLDGPQKKPEGPIQAMMAQSQ 414 S QT R P +K S GP G L P P++A Sbjct: 801 V------SPQTKRP------PTKKG-----SAGPDTPIGNLSSPVS----PVEASFLPEN 839 Query: 415 SLGKGPGPRTDVGAPFGPQGHRDVPFSPDEMVPPSMNSQSGTIGPDHLDHMTPEQIAW-- 472 SL QG +D P + PPS G P + ++P+ + Sbjct: 840 SLSF--------------QGSKDSPATTHSPTPPS---PKGAPTPSAVTPLSPKGVTLPP 882 Query: 473 ----------LKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPPPPYQMTP 522 L +E KQ + S P+G+ P P TP Sbjct: 883 KETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTP 942 Query: 523 SEGWAP----GGTEPFSDGINMPHSLPPRGMAPHPNMPGSQMRLPGFAGMINSEMEGPNV 578 P G P P + P P P + A S GP Sbjct: 943 PAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPAT 1002 Query: 579 PNPASRPGLSGVSWPDD-----VPKIPDGRNFPPGQGIFSGPGRGERFPNPQGLSEEMFQ 633 P+P P V+ P P G + PP S G P P+G Sbjct: 1003 PSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAA 1062 Query: 634 QQLAEKQLGLPPGMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIFPRIPVEGPLSPSRGDF 693 + K G P +++G P P P GP +PS Sbjct: 1063 TLPSPK--GGPATPSLKGA------------------PTPPAATPPSPKGGPATPS---- 1098 Query: 694 PKGIPPQMGPGRELEFGMVPSGMKGDVNLNVNMGSNSQMI---PQKMREAGAGPEEMLKL 750 PKG P M P P KG + + G+ + P P + Sbjct: 1099 PKGAP--MPPAA------TPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPT 1150 Query: 751 RPGGSDMLPAQQKMVPLPFGEH-------PQQEYGMGP-----RPFLPMSQGPGSNSGLR 798 P + P P P G P + G+ P P + P GL Sbjct: 1151 TPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLA 1210 Query: 799 NLREPIGPDQRTNSRLSHMPPLPL------NPSSNPTSLNTAPPVQRGLGRKPLDISVAG 852 P + PP P +P PT+ PP +G P Sbjct: 1211 TPSPKGAPTTPAAT-----PPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPT 1265 Query: 853 SQVHSPGI--NPLKSPTMHQVQSPMLGSP----SGNLKSPQTPSQLAGMLAGPAAAASIK 906 +P L +P +P + +P G SP + P+ S Sbjct: 1266 PPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPG 1325 Query: 907 SPPVLGS----AAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMASPAML 962 +PP G+ A P +P+LPA +P P P G P P PAM Sbjct: 1326 TPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMT 1385 Query: 963 GNVESGGPPPPT----ASQPASVNIPGSLPSSTPYTMPPEPTLSQNPLSIMMSRMSKFAM 1018 GP P+ + PA + + +TP T T S+ L+ Sbjct: 1386 PPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLT----------P 1435 Query: 1019 PSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMGINTQNPRISGPNPVVPMPTLS 1078 P+ TP+ ++ + S P P PS P + P ++ P+P P + Sbjct: 1436 PAVTPV------SLKKAPATSAPKGGPATPSSKGDPTL------PAVTPPSPKEPP---A 1480 Query: 1079 PMGMTQPLSHSNQMPSPNAVGPNIPPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRM--- 1135 P + S +P +G P +P P + P S+ P+ P + Sbjct: 1481 PKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATP----SSRRDPIAPTATLLSK 1536 Query: 1136 GFPQGFPPVQS---PPQQVPFPHNGPSGGQGSFPGGMGFPGEGPLGRPSNLPQSSADAAL 1192 P P ++ P VP P P+ + P E P PS+ ++S+ A+ Sbjct: 1537 KTPATLAPKEALIPPAMTVPSPKKTPA---------IPTPKEAP-ATPSS-KEASSPPAV 1585 Query: 1193 CKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYF 1252 G P +L +P T P +E P A P + P+ K + T Sbjct: 1586 TPSTYKGAPSPKELL---IPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSP-- 1640 Query: 1253 PRGEVPGRKQPQGPGPGFSHMQGMMGEQAPRMGLALPGMGG----------PGPVGTPDI 1302 P + P P + + MG P+ LP G P P TP I Sbjct: 1641 PVTPSSLKDSPTSP----ASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPII 1696 Query: 1303 PLGTAPSMPGHN---------PMRPPAFLQQGMMGP 1329 TAP+ G P+ P + G GP Sbjct: 1697 ---TAPTRKGPQTKKSSATSPPICPDPSAKNGSKGP 1729 Score = 84.3 bits (207), Expect = 7e-16 Identities = 260/1206 (21%), Positives = 386/1206 (32%), Gaps = 219/1206 (18%) Query: 5 NPKVRSSPSGNTQSSPKSKQEVMVRPPTVMSPSGNPQLDSKFSNQGKQGGSASQSQPSPC 64 +PK +PS T SPK V + P +PS ++ F +G + Q+ P+ Sbjct: 860 SPKGAPTPSAVTPLSPKG---VTLPPKETPTPS---VVNLPFPKEGPATPAPKQA-PALS 912 Query: 65 DSKSGGHTPKALPGPGGSMGLKNGAGNGAKGKGKRERSISADSFDQRDPGTPNDDSDIKE 124 + S +A P P G KG + + P TP+ K Sbjct: 913 MTSSSPKKARATPAP-------KGIPASPSPKGAPTPPAATPPSPKGGPATPSP----KW 961 Query: 125 CNSADHIKSQDSQHTPHSMTPSNATAPRSSTPSHGQTTATEPTPAQKTPAKVVYVFSTEM 184 + + P + +P A P ++TP + P+P + P + Sbjct: 962 APTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSP-KGAPTPPAVTPPSPK 1020 Query: 185 ANKAAEAVLKGQVETIVSFHIQNISNNKTERSTAPLNTQISALRNDPKPLPQQPPA--PA 242 + AA KG + +T P A PK P P A P+ Sbjct: 1021 GSPAATPFPKGA--------------STPPAATPPSPKGSPAATPLPKGAPTTPAATLPS 1066 Query: 243 NQDQNSSQNTRLQPTPPIPAP--------APKPAAPPRPLDRESPGVENKLI--PSVGSP 292 + ++ + + PTPP P P P P P P + L P G+P Sbjct: 1067 PKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAP 1126 Query: 293 ASSTPLPPDGTG------PNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGEPPTLG- 345 + PP G P P A TP S ++ PK P P ++ P G Sbjct: 1127 TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL 1186 Query: 346 --ENPDGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPGVLDGPQKKPE 403 +P G L P K + P G L P P+ Sbjct: 1187 ATPSPKGAPTTPAATPPSPKGGLAT------PSPKGAPTTPAATPPSPKGGLATPS--PK 1238 Query: 404 GPIQAMMAQSQSLGKGPGPRTDVGAPFGPQGHRDVPFSPDEMVPPSMNSQSGTIGPDHLD 463 G A S GP GAP +P PPS+ + G P H Sbjct: 1239 GAPTTPAATPPSPKGGPATPPPKGAP-----------TPPAATPPSL--KGGLATPPHKG 1285 Query: 464 HMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPPPPYQMTPS 523 P +V P+G PP TP Sbjct: 1286 APNPA--------------------------------VVTPPSPKGGPATSPPKGAPTP- 1312 Query: 524 EGWAPGGTEPFSDGINMPHSLPPRGMAPHPNM-PGSQMRLPGFAGMINSEMEGPNVPNPA 582 P T P G P + PP+G P + P S P S GP P+ Sbjct: 1313 ----PAATPPSPKG--SPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSK 1366 Query: 583 SRPGLSGVSWPDDVPKIPDGRNFPPGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQLG 642 P + P P G P P RG P+P+G Sbjct: 1367 EGP-----TPPAATPSHKGGPAMTP-----PSPKRGPAIPSPKG---------------- 1400 Query: 643 LPPGMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIFPRIPVEGPLSPSRGDF-PKGIPP-- 699 + P++ IP + P P P + EG +PS+GD P + P Sbjct: 1401 -------DPTSPAV-----IP-----LSPKKAPATP-VTREGAATPSKGDLTPPAVTPVS 1442 Query: 700 -QMGPGRELEFG--MVPSGMKGDVNLNVNMGSNSQMIPQKMREAGAGPEEMLKLRPG--G 754 + P G PS KGD L + + P + A + + P G Sbjct: 1443 LKKAPATSAPKGGPATPSS-KGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMG 1501 Query: 755 SDMLPAQQKMVPLPFGEHPQQEYG-MGPRPFLPMSQGPGSNSGLRNLREPIG--PDQRTN 811 + LPA P P + P L + P + + L P P + Sbjct: 1502 APTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKT 1561 Query: 812 SRLSHMPPLPLNPSSNPTSLNTA--PPVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMH 869 + P PSS S A P +G P ++ + + V SP +P ++PT Sbjct: 1562 PAIPTPKEAPATPSSKEASSPPAVTPSTYKG-APSPKELLIPPA-VTSP--SPKEAPTPP 1617 Query: 870 QVQSPMLGSPSGNLKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAP 929 V P SP K P TP+ + P +S+K P ++ AS ++P Sbjct: 1618 AVTPP---SPE---KGPATPAPKGTPTSPPVTPSSLKDSP---TSPASVTCKMGATVPQA 1668 Query: 930 SPGWTSSPKPP-LQSPGIPPNHKAPLTMASPAMLG--NVESGGPPPPTASQPASVN-IPG 985 S G + P L+ + P ++ + +P G +S PP P++ N G Sbjct: 1669 SKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKG 1728 Query: 986 SLPSSTPYTMPP---EPTLSQNPLSIMMSRMSKFAMP---SSTPLYHDAIKTVASSDDDS 1039 L + P + P + + + S A P +STPL A + V + + Sbjct: 1729 PLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESA 1788 Query: 1040 PPARSPNLPSMNNMPGMGINTQNPRISGPNPVVPMPTLSPMGMTQPLSHSNQMPSPNAVG 1099 + +P+ P +S P P+PTL P P S + SP+ Sbjct: 1789 SVSAAPS----------------PPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSK-- 1830 Query: 1100 PNIPPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFP-PVQSPPQQVPFPHNGP 1158 P P + P L+ PI G + +V M P+ PV +P + P N Sbjct: 1831 PLAPADEDELLP-LIPPEPISGGVPFQSVLV---NMPTPKSAGIPVPTPSAKQPVTKNNK 1886 Query: 1159 SGGQGS 1164 G S Sbjct: 1887 GSGTES 1892 Score = 84.0 bits (206), Expect = 1e-15 Identities = 231/1039 (22%), Positives = 343/1039 (33%), Gaps = 164/1039 (15%) Query: 5 NPKVRSSPSGNTQSSPKS-----KQEVMVRPPTVM--SPSGNPQLDSKFSNQGKQGGSA- 56 +PK +P T SPK + PP V SP G+P + +G S Sbjct: 981 SPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA-----ATPFPKGASTP 1035 Query: 57 -SQSQPSPCDSKSGGHTPKALPG-PGGSMGLKNGAGNGAKGKGKRERSISADSFDQRDPG 114 + + PSP S + PK P P ++ G KG + + P Sbjct: 1036 PAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPA 1095 Query: 115 TPNDDSDIKECNSADHIKSQDSQHTPHSMTPSNATAPRSSTPSHGQTTATEPTP-AQKTP 173 TP+ + PH P T P ++ PS AT P A TP Sbjct: 1096 TPSPKGAPMPPAATPPSPKGGLATPPHKGAP---TTPAATPPSPKGGLATPPPKGAPTTP 1152 Query: 174 AKVVYVFSTEMANKAAEAVLKGQVETIVSFHIQNISNNKTERSTAPLNTQISALRNDPKP 233 A +A + T S + + T P T S P Sbjct: 1153 AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATP 1212 Query: 234 LPQQPPAPANQDQNSSQNTRLQPTPPIPAPAPKPAAPPRPLDRESPGVENKLIPSVGSPA 293 P+ P S + P+P AP A PP P + P P G+P Sbjct: 1213 SPKGAPTTPAATPPSPKGGLATPSPK-GAPTTPAATPPSP--KGGPATP----PPKGAPT 1265 Query: 294 SSTPLPPDGTGPNSTP------NNRAVTPVSQGSNSSSADPKAPPPPPVSSGEPPTLGEN 347 PP G +TP N VTP S +++ PK P PP ++ PP+ Sbjct: 1266 PPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAAT--PPS---- 1319 Query: 348 PDGLSQEQLEHRERSLQTLRDIQRMLFPDEKEFTGAQSGGPQQNPGVLDGPQKKPEGPIQ 407 P G + + P T + GGP P +GP P Sbjct: 1320 PKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPT-TPSSKEGPTPPAATPSH 1378 Query: 408 ----AMMAQSQSLGKG-PGPRTDVGAPFGPQGHRDVPFSPDEMVPPSMNSQSGTIGPDHL 462 AM S G P P+ D +P +P SP + P + ++ G P Sbjct: 1379 KGGPAMTPPSPKRGPAIPSPKGDPTSP------AVIPLSPKK-APATPVTREGAATPSKG 1431 Query: 463 DHMTPEQIAWLKLQQEFYEEKRRKQEQVVVQQCSLQDMMVHQHGPRGVVRGPPPPYQMTP 522 D +TP + + L++ + + V P+ PP P Q+ Sbjct: 1432 D-LTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKE----PPAPKQVAT 1486 Query: 523 SEGWAPGGTEPFSDGINMPHSLPPRGMAPHPNMPGSQMR-LPGFAGMINSEMEGPNVPNP 581 S P G ++ P P P S+ + A +++ + P Sbjct: 1487 SSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKE 1546 Query: 582 ASRPGLSGVSWPDDVPKIPDGRNFPPGQGIFSGPGRGERFPNPQGLSEEMFQQQLAEKQL 641 A P V P P IP + P + P E +P ++ ++ + K+L Sbjct: 1547 ALIPPAMTVPSPKKTPAIPTPKEAP------ATPSSKEA-SSPPAVTPSTYKGAPSPKEL 1599 Query: 642 GLPPGMAMEGIRPSMEMNRMIPGSQRHMEPGNNPIFPRIPVEGPLSPSRGDFPKGIP--P 699 +PP + + + P + P P +GP +P+ PKG P P Sbjct: 1600 LIPPAVTSPSPKEA---------------PTPPAVTPPSPEKGPATPA----PKGTPTSP 1640 Query: 700 QMGPGRELEFGMVPSGMKGDVNLNVNMGSNSQMIPQKMREAGAGPEEMLKLRPGGSDMLP 759 + P + P+ + + V S +P K GP + ++ + P Sbjct: 1641 PVTPSSLKDSPTSPASVTCKMGATVPQASKG--LPAKK-----GPTALKEVLVAPA---P 1690 Query: 760 AQQKMVPLPFGEHPQQEYGMGPRPFLPMSQGPGSNSGLRNLREPIGPDQRTNSRLSHMPP 819 ++ P + PQ + P P+ P + +G + GP LS + P Sbjct: 1691 ESTPIITAPTRKGPQTKKSSATSP--PICPDPSAKNGSK------GP-------LSTVAP 1735 Query: 820 LPLNPSSNPTSLNTAPPVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGSP 879 PL P +S K D S HSP K P L P Sbjct: 1736 APLLPVQKDSSKTA----------KGKDAS------HSP-----KGP---------LAPP 1765 Query: 880 SGNLKSPQTPSQLAGMLAGP--AAAASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTSSP 937 +P T + +L P A+ ++ SPPV A SPV P+LP SSP Sbjct: 1766 ESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPV----PTLPPKQQFLPSSP 1821 Query: 938 KPPLQSPGIP-----PNHKAPLTMASP--------AMLGNV---ESGGPPPPT--ASQPA 979 L+SP P + PL P ++L N+ +S G P PT A QP Sbjct: 1822 GLVLESPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPV 1881 Query: 980 SVNIPGSLPSSTPYTMPPE 998 + N GS S PE Sbjct: 1882 TKNNKGSGTESDSDESVPE 1900 Score = 67.4 bits (163), Expect = 9e-11 Identities = 163/751 (21%), Positives = 236/751 (31%), Gaps = 131/751 (17%) Query: 679 RIPVEGPLSPSRG--DFPKGIPPQMGPGRELEFGMVPSGMKGDVNLNVNMGSNSQMIPQK 736 RIPV PL + P + + ++L+ VP+ ++G G ++ P Sbjct: 502 RIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQ--TVPASLEGAPFSPAQAGLTTKKDPTV 559 Query: 737 MREAGAGPEEMLKLRPGGSD---------MLPAQQKMVPLPFGEHPQQEYGMGPRPFLPM 787 + A P+ + S L + PLP G+ P + Sbjct: 560 LPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGK---------PASSMTS 610 Query: 788 SQGPGSNSGLRNLREPIGPDQRTNSRLSHM--PPLPLNPSSNPTSLNTAPPVQRGLGRKP 845 G S++ + GPD S + P + P + AP +G Sbjct: 611 PLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYT 670 Query: 846 LDIS--VAGSQVHSPGINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGMLAGPAAAA 903 S + G+ +P +P+K T+ + P++ + S N +P LA A Sbjct: 671 TTASPFLEGTVSLAPKNHPVKEGTLTTL--PLVPTASENCPVAPSPQNTCAPLATLVLAP 728 Query: 904 SIKSPPVLGSAAASPVHLKSPSLPAPSPGWTSSPKPPLQSPGIPPNHKAPLTMASPAMLG 963 I P + SPSLP G PP K ++ + L Sbjct: 729 EI------------PKSVPSPSLP---------------PAGTPPGTKKVDGISHTSALA 761 Query: 964 NVESGGPPPPTASQPAS--VNIPGSLP-----------SSTPYTMPPEPTLSQNPLSIMM 1010 V S PT AS + G+L S +P T P + Sbjct: 762 PVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPI 821 Query: 1011 SRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMGINTQNPRISGPNP 1070 +S P + + S D SP PS P P+ Sbjct: 822 GNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAP------------TPSA 869 Query: 1071 VVPMPTLSPMGMTQPLSHSNQMPSPNAVGPNIPPHGVPMGP--------GLMSHNPIMGH 1122 V P LSP G+T P + P+P+ V P G P P + S +P Sbjct: 870 VTP---LSPKGVTLP---PKETPTPSVVNLPFPKEG-PATPAPKQAPALSMTSSSPKKAR 922 Query: 1123 GSQEPPMVPQGRMGFPQGFPPVQSPPQ-----QVPFPHNGPSGGQGSFPGGMGFPG-EGP 1176 + P +P PP +PP P P P+ + P G P P Sbjct: 923 ATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSP 982 Query: 1177 LGRPSNLPQSSADAALCKPGGPGGPDSFTVLGNSMPSVFTDPDLQEVIRPGATGIPE--- 1233 G P+ A P GGP + + G P T P + P AT P+ Sbjct: 983 KGAPT-------PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKG--SPAATPFPKGAS 1033 Query: 1234 FDLSRIIPSEKPSQTLQYFPRG--EVPGRKQPQGP-GPGFSHMQGMMGEQAPRMGLALPG 1290 + PS K S P+G P P GP ++G AP A P Sbjct: 1034 TPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKG-----APTPPAATP- 1087 Query: 1291 MGGPGPVGTPDIPLGTAPSMPGHNPMRPPAFLQQGMMGPHHRMMSPAQSTMPGQPT--LM 1348 P P G P P MP P P + G+ P H+ + P P L Sbjct: 1088 ---PSPKGGPATPSPKGAPMP---PAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLA 1141 Query: 1349 SNPAAAVGMIP-GKDRGPAGLYTHPGPVGSP 1378 + P P P G P P G+P Sbjct: 1142 TPPPKGAPTTPAATPPSPKGGLATPPPKGAP 1172 Score = 54.7 bits (130), Expect = 6e-07 Identities = 99/374 (26%), Positives = 128/374 (34%), Gaps = 64/374 (17%) Query: 6 PKVRSSPSGNTQSSPKSKQEV------MVRPPTVMSPSGNPQLDSKFSNQGKQGGSASQ- 58 PK SPS +P ++V P SP P DS S G+ + Sbjct: 731 PKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYL 790 Query: 59 -SQPSPCDSKSGGHTPKALPGPGGSMGLKNGAGNGAKGKGKRERSISADSFDQRDPGTPN 117 PSP T K P GS G GN + P +P Sbjct: 791 ADSPSPLGVSVSPQT-KRPPTKKGSAGPDTPIGNLSS------------------PVSPV 831 Query: 118 DDSDIKECNSADHIKSQDSQHTPHSMTPSN---ATAPRSSTP--SHGQTTATEPTPAQKT 172 + S + E NS S+DS T HS TP + A P + TP G T + TP T Sbjct: 832 EASFLPE-NSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETP---T 887 Query: 173 PAKVVYVFSTEMANKAAEAVLKGQVETIVSFHIQNISNNKTERSTAPLNTQIS-ALRNDP 231 P+ V F E A A + ++ S S K + AP S + + P Sbjct: 888 PSVVNLPFPKE--GPATPAPKQAPALSMTSS-----SPKKARATPAPKGIPASPSPKGAP 940 Query: 232 KPLPQQPPAPANQDQNSSQNTRLQP---TPPIP-----------APAPKPAAPPRPLDRE 277 P PP+P S P TPP P AP P A PP P Sbjct: 941 TPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSP---- 996 Query: 278 SPGVENKLIPSVGSPASSTPLPPDGTGPNSTPNNR-AVTPVSQGSNSSSADPKAPPPPPV 336 G +P + TP P G+ P +TP + A TP + S P A P P Sbjct: 997 KGGPATPSPKGAPTPPAVTPPSPKGS-PAATPFPKGASTPPAATPPSPKGSPAATPLPKG 1055 Query: 337 SSGEPPTLGENPDG 350 + P +P G Sbjct: 1056 APTTPAATLPSPKG 1069 Score = 44.7 bits (104), Expect = 7e-04 Identities = 112/495 (22%), Positives = 174/495 (35%), Gaps = 101/495 (20%) Query: 786 PMSQGPGSNSGLRNLREPIGPDQ---RTNSRLSHMPPLPLNPSSNPTSLNTAP------- 835 P S + + L PI P + N S + P P S P ++T P Sbjct: 161 PPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPM 220 Query: 836 -PVQRGLGRKP-----LDISVAGSQV------------HSPGINPLKSPTMH------QV 871 +Q G+ P +++A QV +PG LK P Sbjct: 221 ASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLST 280 Query: 872 QSPMLGSPSGNLKSPQTPSQLA---GMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPA 928 QS + + S P TP G P +S S +LG P L P++ Sbjct: 281 QSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTG--PSALSDPTVKT 338 Query: 929 PSPGWTSSPKP-PLQSPGIPP----NHKAPLTMAS-PAMLGNVESGGPPPPTASQPASVN 982 S +S+ P Q IPP N P T+A+ P + +V+ G P+ + + Sbjct: 339 ISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKG----PSTISSITCS 394 Query: 983 IPGSLPSSTPYTMPPEPTL----SQN-----PLSIMMSRMSKFAMPSSTPLYHDAIKTVA 1033 GSL +T +++ P +L S N PL M S +TPL T+A Sbjct: 395 PSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSV----GTTPLVVTNPCTIA 450 Query: 1034 SSDDDSPPARSPNLPSMNNMPGMGINTQNPRISGPNPVVPMPTLSPMGMTQPLSHSNQMP 1093 ++ + + P M++ P I +P PV P + + T + S +P Sbjct: 451 AAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLP 510 Query: 1094 SPNAVGPNIPPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPPVQS------P 1147 P + N+P + P ++ VP G P F P Q+ Sbjct: 511 DPEDL-KNLPSSVLVKFP-----------TQKDLQTVPASLEGAP--FSPAQAGLTTKKD 556 Query: 1148 PQQVPF----PHNGPSGGQGSFPGGMGFPGEG-----------PLGRPSNLPQS----SA 1188 P +P P N PS S + E P+G+P++ S ++ Sbjct: 557 PTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNS 616 Query: 1189 DAALCKPGGPGGPDS 1203 A++ K GPDS Sbjct: 617 SASVIKTDSYAGPDS 631 Score = 41.6 bits (96), Expect = 0.006 Identities = 73/321 (22%), Positives = 106/321 (33%), Gaps = 36/321 (11%) Query: 744 PEEMLKLRPGGSDMLPAQQ-KMVPLPFGEHPQQEYGMG-PRPFLPMSQGPGSNS---GLR 798 P E + P LP Q + LP +G P P LP P Sbjct: 2 PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61 Query: 799 NLREPIGPDQRTNSRLSHMPPLPLNPSSNPTSLNTAPPVQRGLGRKPLDISVAGSQVHSP 858 N P P T + P P + S L TAP L Sbjct: 62 NQASPF-PSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNL-------------- 106 Query: 859 GINPLKSPTMHQVQSPMLGSPSGNLKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAASP 918 I P SP + SPM+ S P L + +S P +L S + Sbjct: 107 -IGPPISPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVA 165 Query: 919 VHLKSPSLPAPSPGWTSSPKPPLQS--PGIPPNHKAPLTMASPAMLGNVESGGPPPPTAS 976 V + +P S PK L + PN K T + P ++ V P + Sbjct: 166 VAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKG--TPSPPCIVSTVPYHCVTPMASI 223 Query: 977 QPASVNIPGSLPSSTPYTMPP---EPTLS------QNPLSIMMSRMSKFAMPSSTPLYHD 1027 Q ++P + P++T P + T+S QNP S +S + P++ L Sbjct: 224 QSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGS--LSLKGPVSPPAALSLSTQ 281 Query: 1028 AIKTVASSDDDSPPARSPNLP 1048 ++ V SS + P P+ P Sbjct: 282 SLPVVTSSQKTAGPNTPPDFP 302 Score = 35.4 bits (80), Expect = 0.40 Identities = 78/349 (22%), Positives = 115/349 (32%), Gaps = 79/349 (22%) Query: 193 LKGQVETIVSFHIQNISNNKTERSTAPLNTQISALRNDPKPLPQQPP--APANQDQNSSQ 250 + G+ V Q + + E + P+++ +S +P P PP +PA Q S Sbjct: 1 MPGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSA 60 Query: 251 NTRLQPTP--------PIPAPAPK------------PAAP------------PRPLDRES 278 + P P P+ P P+ P AP P L S Sbjct: 61 ANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALAS 120 Query: 279 PGVENKLIPSVGSPASSTPLPPDGTGPNSTPNNRAVTP-----------VSQGSNSSSAD 327 P + L G+P+SS PL P+S + A P GS + + Sbjct: 121 PMIAPTL---KGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSA 177 Query: 328 PKAPPPPPVSSGEPPT-LGENPDG------------------LSQEQLEHRERSLQTLRD 368 P AP P + + P+ + NP G ++ Q T Sbjct: 178 PIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTT 237 Query: 369 IQRMLFPDEKEFTGAQSGGPQQNPGVLDGPQKKPEGPIQAMMAQSQSLGKGPGPRTDVGA 428 + P K+ T + QNPG L K P P A+ +QSL T Sbjct: 238 TLAIASPQVKDTTISSVLISPQNPGSLS--LKGPVSPPAALSLSTQSL----PVVTSSQK 291 Query: 429 PFGPQGHRDVPFSPDEMVPPSMNSQSGTI------GPDHLDHMTPEQIA 471 GP D P S + P S G++ GP L T + I+ Sbjct: 292 TAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTIS 340 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.310 0.132 0.402 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 84,407,404 Number of Sequences: 37866 Number of extensions: 6309321 Number of successful extensions: 60909 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 380 Number of HSP's successfully gapped in prelim test: 2228 Number of HSP's that attempted gapping in prelim test: 25103 Number of HSP's gapped (non-prelim): 21662 length of query: 1426 length of database: 18,247,518 effective HSP length: 115 effective length of query: 1311 effective length of database: 13,892,928 effective search space: 18213628608 effective search space used: 18213628608 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.