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Search of human proteins with 67782349
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|67782349 lysyl oxidase-like 4 precursor [Homo sapiens]
(756 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|67782349 lysyl oxidase-like 4 precursor [Homo sapiens] 1615 0.0
gi|4505011 lysyl oxidase-like 2 precursor [Homo sapiens] 874 0.0
gi|14211943 lysyl oxidase-like 3 precursor [Homo sapiens] 870 0.0
gi|148539844 deleted in malignant brain tumors 1 isoform c precu... 271 2e-72
gi|148539842 deleted in malignant brain tumors 1 isoform b precu... 271 2e-72
gi|148539840 deleted in malignant brain tumors 1 isoform a precu... 270 5e-72
gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens] 269 6e-72
gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens] 268 1e-71
gi|18152779 scavenger receptor cysteine rich domain containing, ... 251 2e-66
gi|4506143 neurotrypsin precursor [Homo sapiens] 228 1e-59
gi|20149540 lysyl oxidase preproprotein [Homo sapiens] 221 1e-57
gi|50659091 scavenger receptor cysteine-rich type 1 precursor [H... 220 3e-57
gi|67782346 lysyl oxidase-like 1 preproprotein [Homo sapiens] 214 2e-55
gi|222352122 hypothetical protein LOC284297 [Homo sapiens] 213 4e-55
gi|44889963 CD163 antigen isoform b [Homo sapiens] 213 5e-55
gi|44662834 CD163 antigen isoform a [Homo sapiens] 213 5e-55
gi|5174411 CD5 molecule-like [Homo sapiens] 164 3e-40
gi|239752563 PREDICTED: hypothetical protein [Homo sapiens] 142 9e-34
gi|194018748 CD6 molecule [Homo sapiens] 134 3e-31
gi|20357512 macrophage scavenger receptor 1 isoform type 1 [Homo... 120 4e-27
gi|5031863 galectin 3 binding protein [Homo sapiens] 113 7e-25
gi|47271477 scavenger receptor class A, member 5 [Homo sapiens] 106 9e-23
gi|5803080 macrophage receptor with collagenous structure [Homo ... 100 4e-21
gi|187936955 HHIP-like protein 1 isoform a [Homo sapiens] 99 1e-20
gi|20357515 macrophage scavenger receptor 1 isoform type 3 [Homo... 57 5e-08
gi|119392081 complement factor I preproprotein [Homo sapiens] 42 0.002
gi|148612825 Rap GTPase interactor [Homo sapiens] 37 0.089
gi|166197668 CD5 molecule [Homo sapiens] 35 0.26
gi|239753316 PREDICTED: similar to Rho guanine nucleotide exchan... 33 0.98
gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo sa... 33 0.98
>gi|67782349 lysyl oxidase-like 4 precursor [Homo sapiens]
Length = 756
Score = 1615 bits (4182), Expect = 0.0
Identities = 756/756 (100%), Positives = 756/756 (100%)
Query: 1 MAWSPPATLFLFLLLLGQPPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDD 60
MAWSPPATLFLFLLLLGQPPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDD
Sbjct: 1 MAWSPPATLFLFLLLLGQPPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDD 60
Query: 61 NFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVS 120
NFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVS
Sbjct: 61 NFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVS 120
Query: 121 DCSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVE 180
DCSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVE
Sbjct: 121 DCSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVE 180
Query: 181 VKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTN 240
VKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTN
Sbjct: 181 VKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTN 240
Query: 241 KNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPKTKPQ 300
KNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPKTKPQ
Sbjct: 241 KNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPKTKPQ 300
Query: 301 RKGSWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREA 360
RKGSWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREA
Sbjct: 301 RKGSWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREA 360
Query: 361 LFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQ 420
LFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQ
Sbjct: 361 LFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQ 420
Query: 421 VRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWF 480
VRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWF
Sbjct: 421 VRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWF 480
Query: 481 WSGTPRAQEVVMSGVRCSGTELALQQCQRHGPVHCSHGGGRFLAGVSCMDSAPDLVMNAQ 540
WSGTPRAQEVVMSGVRCSGTELALQQCQRHGPVHCSHGGGRFLAGVSCMDSAPDLVMNAQ
Sbjct: 481 WSGTPRAQEVVMSGVRCSGTELALQQCQRHGPVHCSHGGGRFLAGVSCMDSAPDLVMNAQ 540
Query: 541 LVQETAYLEDRPLSQLYCAHEENCLSKSADHMDWPYGYRRLLRFSTQIYNLGRTDFRPKT 600
LVQETAYLEDRPLSQLYCAHEENCLSKSADHMDWPYGYRRLLRFSTQIYNLGRTDFRPKT
Sbjct: 541 LVQETAYLEDRPLSQLYCAHEENCLSKSADHMDWPYGYRRLLRFSTQIYNLGRTDFRPKT 600
Query: 601 GRDSWVWHQCHRHYHSIEVFTHYDLLTLNGSKVAEGHKASFCLEDTNCPTGLQRRYACAN 660
GRDSWVWHQCHRHYHSIEVFTHYDLLTLNGSKVAEGHKASFCLEDTNCPTGLQRRYACAN
Sbjct: 601 GRDSWVWHQCHRHYHSIEVFTHYDLLTLNGSKVAEGHKASFCLEDTNCPTGLQRRYACAN 660
Query: 661 FGEQGVTVGCWDTYRHDIDCQWVDITDVGPGNYIFQVIVNPHYEVAESDFSNNMLQCRCK 720
FGEQGVTVGCWDTYRHDIDCQWVDITDVGPGNYIFQVIVNPHYEVAESDFSNNMLQCRCK
Sbjct: 661 FGEQGVTVGCWDTYRHDIDCQWVDITDVGPGNYIFQVIVNPHYEVAESDFSNNMLQCRCK 720
Query: 721 YDGHRVWLHNCHTGNSYPANAELSLEQEQRLRNNLI 756
YDGHRVWLHNCHTGNSYPANAELSLEQEQRLRNNLI
Sbjct: 721 YDGHRVWLHNCHTGNSYPANAELSLEQEQRLRNNLI 756
>gi|4505011 lysyl oxidase-like 2 precursor [Homo sapiens]
Length = 774
Score = 874 bits (2259), Expect = 0.0
Identities = 407/740 (55%), Positives = 527/740 (71%), Gaps = 23/740 (3%)
Query: 21 PSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAAL 80
P P ++ +LRL G + K EGR+EV + GQWGTVCDD+F+I A V CR+LG+ A
Sbjct: 47 PQAPANVAKIQLRLAGQKRKHSEGRVEVYYDGQWGTVCDDDFSIHAAHVVCRELGYVEAK 106
Query: 81 TWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGY 140
+W S+ YG+GEGPIWLDN+ C G E++L C SNGWGV+DC H+EDVGV+C +R G+
Sbjct: 107 SWTASSSYGKGEGPIWLDNLHCTGNEATLAACTSNGWGVTDCKHTEDVGVVCSDKRIPGF 166
Query: 141 -LSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNN 199
++ N + ++E++R++ IL++ ++ +PV EG VEVK W+Q+CD+ WT N
Sbjct: 167 KFDNSLINQIENLNIQVEDIRIRAILSTYRKRTPVMEGYVEVKEGKTWKQICDKHWTAKN 226
Query: 200 SRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMA 259
SRVVCGM GFP E ++ Y+ + + K +W + C GTE H++
Sbjct: 227 SRVVCGMFGFPGERTYNTKVYK-------------MFASRRKQRYWPFSMDCTGTEAHIS 273
Query: 260 NC----QVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRS 315
+C QV + P + C G+ AVVSCV G F P RK E+P VRLR
Sbjct: 274 SCKLGPQVSLDPMKNV---TCENGLPAVVSCVPGQVFSPDGPSRFRKAYKPEQPLVRLRG 330
Query: 316 GAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHL 375
GA +GEGRVEVL N +WGTVCD +W+L+SASVVCR+LGFGSA+EA+ G+RLGQG+GPIHL
Sbjct: 331 GAYIGEGRVEVLKNGEWGTVCDDKWDLVSASVVCRELGFGSAKEAVTGSRLGQGIGPIHL 390
Query: 376 SEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEGLLE 435
+E++C G E+++ DC SQ GC HE DA VRCN P MG Q ++RL GGR P EG +E
Sbjct: 391 NEIQCTGNEKSIIDCKFNAESQ-GCNHEEDAGVRCNTPAMGLQKKLRLNGGRNPYEGRVE 449
Query: 436 VQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGV 495
V VE NG WG VC +NWG+ EAMV CRQLGLGFA +A++ETW+W G + +VVMSGV
Sbjct: 450 VLVERNGSLVWGMVCGQNWGIVEAMVVCRQLGLGFASNAFQETWYWHGDVNSNKVVMSGV 509
Query: 496 RCSGTELALQQCQRHGP-VHCSHGGGRFLAGVSCMDSAPDLVMNAQLVQETAYLEDRPLS 554
+CSGTEL+L C+ G V C GG ++ AGV+C ++APDLV+NA++VQ+T YLEDRP+
Sbjct: 510 KCSGTELSLAHCRHDGEDVACPQGGVQYGAGVACSETAPDLVLNAEMVQQTTYLEDRPMF 569
Query: 555 QLYCAHEENCLSKSADHMDWPYGYRRLLRFSTQIYNLGRTDFRPKTGRDSWVWHQCHRHY 614
L CA EENCLS SA D GYRRLLRFS+QI+N G++DFRPK GR +W+WH CHRHY
Sbjct: 570 MLQCAMEENCLSASAAQTDPTTGYRRLLRFSSQIHNNGQSDFRPKNGRHAWIWHDCHRHY 629
Query: 615 HSIEVFTHYDLLTLNGSKVAEGHKASFCLEDTNCPTGLQRRYACANFGEQGVTVGCWDTY 674
HS+EVFTHYDLL LNG+KVAEGHKASFCLEDT C +Q+ Y CANFG+QG+T+GCWD Y
Sbjct: 630 HSMEVFTHYDLLNLNGTKVAEGHKASFCLEDTECEGDIQKNYECANFGDQGITMGCWDMY 689
Query: 675 RHDIDCQWVDITDVGPGNYIFQVIVNPHYEVAESDFSNNMLQCRCKYDGHRVWLHNCHTG 734
RHDIDCQWVDITDV PG+Y+FQV++NP++EVAESD+SNN+++CR +YDGHR+W++NCH G
Sbjct: 690 RHDIDCQWVDITDVPPGDYLFQVVINPNFEVAESDYSNNIMKCRSRYDGHRIWMYNCHIG 749
Query: 735 NSYPANAELSLEQEQRLRNN 754
S+ E E L NN
Sbjct: 750 GSFSEETEKKFEHFSGLLNN 769
>gi|14211943 lysyl oxidase-like 3 precursor [Homo sapiens]
Length = 753
Score = 870 bits (2248), Expect = 0.0
Identities = 418/762 (54%), Positives = 523/762 (68%), Gaps = 26/762 (3%)
Query: 3 WSPPATLFLFLL--LLGQPPPSR-PQSLGTT---KLRLVGPESKPEEGRLEVLHQGQWGT 56
WSP L L LG P PS P+ + + RL G KP EGR+E+ G+WGT
Sbjct: 9 WSPWGLLLCLLCSSCLGSPSPSTGPEKKAGSQGLRFRLAGFPRKPYEGRVEIQRAGEWGT 68
Query: 57 VCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNG 116
+CDD+F +Q A + CR+LGF A W HSAKYG G G IWLDN+ C GTE S+ +C S G
Sbjct: 69 ICDDDFTLQAAHILCRELGFTEATGWTHSAKYGPGTGRIWLDNLSCSGTEQSVTECASRG 128
Query: 117 WGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTE 176
WG SDC+H ED GVIC +R G+ V ++EEVR++P + ++ PVTE
Sbjct: 129 WGNSDCTHDEDAGVICKDQRLPGFSDSNVIEV--EHHLQVEEVRIRPAVGWGRRPLPVTE 186
Query: 177 GAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLK 236
G VEV+ W QVCD+GW+ +NS VVCGMLGFPSE V++ +YR L
Sbjct: 187 GLVEVRLPDGWSQVCDKGWSAHNSHVVCGMLGFPSEKRVNAAFYR-------------LL 233
Query: 237 SLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPK 296
+ ++SF +H V C+GTE H++ C ++ A R CPGG AVVSCV GP +
Sbjct: 234 AQRQQHSFGLHGVACVGTEAHLSLCSLEFYRANDTAR--CPGGGPAVVSCVPGPVYAASS 291
Query: 297 -TKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFG 355
K Q++ E RVRL+ GA GEGRVEVL WGTVCD +W+L +ASVVCR+LGFG
Sbjct: 292 GQKKQQQSKPQGEARVRLKGGAHPGEGRVEVLKASTWGTVCDRKWDLHAASVVCRELGFG 351
Query: 356 SAREALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNM 415
SAREAL GAR+GQG+G IHLSEVRC G E +L CP + C H DA VRCN+P
Sbjct: 352 SAREALSGARMGQGMGAIHLSEVRCSGQELSLWKCPHKNITAEDCSHSQDAGVRCNLPYT 411
Query: 416 GFQNQVRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAY 475
G + ++RL+GGR EG +EVQ+ G RWG +C ++WG EAMVACRQLGLG+A H
Sbjct: 412 GAETRIRLSGGRSQHEGRVEVQIGGPGPLRWGLICGDDWGTLEAMVACRQLGLGYANHGL 471
Query: 476 KETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGP-VHCSHGGGRFLAGVSCMDSAPD 534
+ETW+W + EVVMSGVRC+GTEL+L QC HG + C G RF AGV C ++A D
Sbjct: 472 QETWYWD-SGNITEVVMSGVRCTGTELSLDQCAHHGTHITCKRTGTRFTAGVICSETASD 530
Query: 535 LVMNAQLVQETAYLEDRPLSQLYCAHEENCLSKSADHMDWPYGYRRLLRFSTQIYNLGRT 594
L++++ LVQETAY+EDRPL LYCA EENCL+ SA +WPYG+RRLLRFS+QI+NLGR
Sbjct: 531 LLLHSALVQETAYIEDRPLHMLYCAAEENCLASSARSANWPYGHRRLLRFSSQIHNLGRA 590
Query: 595 DFRPKTGRDSWVWHQCHRHYHSIEVFTHYDLLTLNGSKVAEGHKASFCLEDTNCPTGLQR 654
DFRPK GR SWVWH+CH HYHS+++FTHYD+LT NG+KVAEGHKASFCLEDT C + +
Sbjct: 591 DFRPKAGRHSWVWHECHGHYHSMDIFTHYDILTPNGTKVAEGHKASFCLEDTECQEDVSK 650
Query: 655 RYACANFGEQGVTVGCWDTYRHDIDCQWVDITDVGPGNYIFQVIVNPHYEVAESDFSNNM 714
RY CANFGEQG+TVGCWD YRHDIDCQW+DITDV PGNYI QV++NP++EVAESDF+NN
Sbjct: 651 RYECANFGEQGITVGCWDLYRHDIDCQWIDITDVKPGNYILQVVINPNFEVAESDFTNNA 710
Query: 715 LQCRCKYDGHRVWLHNCHTGNSYPANAELSLEQEQRLRNNLI 756
++C CKYDGHR+W+HNCH G+++ A E+ +N I
Sbjct: 711 MKCNCKYDGHRIWVHNCHIGDAFSEEANRRFERYPGQTSNQI 752
>gi|148539844 deleted in malignant brain tumors 1 isoform c precursor
[Homo sapiens]
Length = 2403
Score = 271 bits (692), Expect = 2e-72
Identities = 196/539 (36%), Positives = 257/539 (47%), Gaps = 66/539 (12%)
Query: 22 SRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALT 81
S P+S + LRLV + + GR+EVL++G WGTVCDD++ +A V CRQLG A +
Sbjct: 584 SGPES--SLALRLVNGGDRCQ-GRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATS 640
Query: 82 WAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGY- 140
+A++GQG GPI LD+VRC G ES L C +NGW +C H ED GVIC + R
Sbjct: 641 APGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTP 700
Query: 141 LSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNS 200
+T+S P E L L + S +G VEV Y G W VCD W N++
Sbjct: 701 RPDTLSTITLPPSTVGSESSLTLRLVNG---SDRCQGRVEVLYRGSWGTVCDDSWDTNDA 757
Query: 201 RVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHM 258
VVC L G+ + P ++ + + + + D V C G E ++
Sbjct: 758 NVVCRQLGCGWATSAPGNARFGQGSGPIVLDD------------------VRCSGHESYL 799
Query: 259 ANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRP---PKTKPQRKGSWA---EEPRVR 312
+C P G L C A V C RP P T P S A +R
Sbjct: 800 WSC-----PHNGWLSHNCGHHEDAGVICSVS-QSRPTPSPDTWPTSHASTAGPESSLALR 853
Query: 313 LRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGP 372
L +G +GRVEVL WGTVCD W+ A+VVCRQLG G A A AR GQG GP
Sbjct: 854 LVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGP 913
Query: 373 IHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRC------NVPNMGFQNQVRLAGG 426
I L +VRC GYE L CP + CQH DA V C + P+ + L
Sbjct: 914 IVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPAS 973
Query: 427 RIPEEGLLEVQVEVNGVPR------------WGSVCSENWGLTEAMVACRQLGLGFAIHA 474
+ E L +++ VNG R WG+VC ++W +A V CRQLG G+A+ A
Sbjct: 974 TVGSESSLALRL-VNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSA 1032
Query: 475 YKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPV--HCSHGGGRFLAGVSCMDS 531
F G + +V+ VRCSG E L C +G + +C H AGV C S
Sbjct: 1033 PGNARFGQG---SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSED---AGVICSAS 1085
Score = 270 bits (691), Expect = 3e-72
Identities = 195/541 (36%), Positives = 257/541 (47%), Gaps = 77/541 (14%)
Query: 32 LRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQG 91
LRLV + + + GR+E+L++G WGTVCDD++ +A V CRQLG A++ +A +GQG
Sbjct: 102 LRLVNGDGRCQ-GRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQG 160
Query: 92 EGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGP 151
GPI LD+VRC G ES L C NGW +C H ED GVIC +A P
Sbjct: 161 SGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVIC--------------SAAQP 206
Query: 152 QGRRLEE---VRLKPILASAKQHSPVT----------EGAVEVKYEGHWRQVCDQGWTMN 198
Q E VR+ P + + S + G VEV Y G W VCD W N
Sbjct: 207 QSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTN 266
Query: 199 NSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEP 256
++ VVC L G+ P ++ + + + + D V C G E
Sbjct: 267 DANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD------------------VRCSGHES 308
Query: 257 HMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRP---PKTKPQRKGSWA---EEPR 310
++ +C P G L C A V C A P RP P T P S A
Sbjct: 309 YLWSC-----PHNGWLTHNCGHSEDAGVICSA-PQSRPTPSPDTWPTSHASTAGPESSLA 362
Query: 311 VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGL 370
+RL +G +GRVEVL WGTVCD W+ A+VVCRQLG G A A AR GQG
Sbjct: 363 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGS 422
Query: 371 GPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCN-------VPNMGFQNQVRL 423
GPI L +VRC GYE L CP + CQH DA V C+ +P ++ L
Sbjct: 423 GPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSDTLPTITLPASTVGSESSL 482
Query: 424 AGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSG 483
A + + +VEV WG+VC ++W +A V CRQLG G+A+ A F G
Sbjct: 483 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQG 542
Query: 484 TPRAQEVVMSGVRCSGTELALQQCQRHGPV--HCSHGGGRFLAGVSCMDSAPDLVMNAQL 541
+ +V+ VRCSG E L C +G + +C H AGV C S P+ + +L
Sbjct: 543 ---SGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSED---AGVIC--SGPESSLALRL 594
Query: 542 V 542
V
Sbjct: 595 V 595
Score = 263 bits (672), Expect = 4e-70
Identities = 185/519 (35%), Positives = 245/519 (47%), Gaps = 57/519 (10%)
Query: 19 PPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEA 78
PP S + LRLV + GR+EVL++G WGTVCDD + +A V CRQLG
Sbjct: 221 PPVPTEGSESSLALRLVNGGDRCR-GRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGW 279
Query: 79 ALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHR 138
A++ +A++GQG GPI LD+VRC G ES L C NGW +C HSED GVIC + R
Sbjct: 280 AMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSR 339
Query: 139 GYLSETV-----SNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQ 193
S ++ GP+ + L+ + + +G VEV Y G W VCD
Sbjct: 340 PTPSPDTWPTSHASTAGPE----SSLALRLVNGGDR-----CQGRVEVLYRGSWGTVCDD 390
Query: 194 GWTMNNSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTC 251
W +++ VVC L G+ + P ++ + + + + D V C
Sbjct: 391 SWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD------------------VRC 432
Query: 252 LGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEEPRV 311
G E ++ +C P G L C A V C P T P +
Sbjct: 433 SGYESYLWSC-----PHNGWLSHNCQHSEDAGVIC---SDTLPTITLPASTVGSESSLAL 484
Query: 312 RLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLG 371
RL +G +GRVEVL WGTVCD W+ A+VVCRQLG G A A AR GQG G
Sbjct: 485 RLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSG 544
Query: 372 PIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEE 431
PI L +VRC G E L CP + C H DA V C+ P +RL G +
Sbjct: 545 PIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSL--ALRLVNGGDRCQ 602
Query: 432 GLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVV 491
G +EV + WG+VC ++W +A V CRQLG G+A A F G + +V
Sbjct: 603 GRVEVLYRGS----WGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQG---SGPIV 655
Query: 492 MSGVRCSGTELALQQCQRHGPV--HCSHGGGRFLAGVSC 528
+ VRCSG E L C +G + +C H AGV C
Sbjct: 656 LDDVRCSGHESYLWSCPNNGWLSHNCGHHED---AGVIC 691
Score = 261 bits (667), Expect = 2e-69
Identities = 196/550 (35%), Positives = 253/550 (46%), Gaps = 70/550 (12%)
Query: 18 QPPPSRPQSLGTTKLRLVGPESKPE----------EGRLEVLHQGQWGTVCDDNFAIQEA 67
+P PS P + T+ GPES +GR+EVL++G WGTVCDD++ +A
Sbjct: 828 RPTPS-PDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDA 886
Query: 68 TVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSED 127
V CRQLG A + +A++GQG GPI LD+VRC G ES L C NGW +C HSED
Sbjct: 887 NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSED 946
Query: 128 VGVICHPRRHRGYLS-ETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGH 186
GVIC S +T+ P E L L + +G VEV Y+G
Sbjct: 947 AGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDR---CQGRVEVLYQGS 1003
Query: 187 WRQVCDQGWTMNNSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSF 244
W VCD W N++ VVC L G+ P ++ + + + + D
Sbjct: 1004 WGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDD-------------- 1049
Query: 245 WIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRP---PKTKPQR 301
V C G E ++ +C P G L C A V C A RP P T P
Sbjct: 1050 ----VRCSGHESYLWSC-----PHNGWLSHNCGHSEDAGVICSAS-QSRPTPSPDTWPTS 1099
Query: 302 KGSWA---EEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAR 358
S A +RL +G +GRVEVL WGTVCD W+ A+VVCRQLG G A
Sbjct: 1100 HASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAM 1159
Query: 359 EALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNV------ 412
A AR GQG GPI L +VRC G+E L CP + C H DA V C+
Sbjct: 1160 SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPT 1219
Query: 413 --PNMGFQNQVRLAGG------RIPEEG-LLEVQVEVNGVPRWGSVCSENWGLTEAMVAC 463
P+ + AG R+ G + +VEV WG+VC + W +A V C
Sbjct: 1220 PSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVC 1279
Query: 464 RQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPV--HCSHGGGR 521
RQLG G+A A F G + +V+ VRCSG E L C +G + +C H
Sbjct: 1280 RQLGCGWATSAPGNARFGQG---SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHED- 1335
Query: 522 FLAGVSCMDS 531
AGV C S
Sbjct: 1336 --AGVICSAS 1343
Score = 261 bits (667), Expect = 2e-69
Identities = 196/554 (35%), Positives = 253/554 (45%), Gaps = 61/554 (11%)
Query: 2 AWSPPATLFLFLLLLGQPPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDN 61
+WS P+ L + L P S S + LRLV + + GR+EVL+QG WGTVCDD+
Sbjct: 956 SWSTPSPDTLPTITL---PASTVGSESSLALRLVNGGDRCQ-GRVEVLYQGSWGTVCDDS 1011
Query: 62 FAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSD 121
+ +A V CRQLG A++ +A++GQG GPI LD+VRC G ES L C NGW +
Sbjct: 1012 WDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN 1071
Query: 122 CSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEV 181
C HSED GVIC + R T S P + +G VEV
Sbjct: 1072 CGHSEDAGVICSASQSR----PTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEV 1127
Query: 182 KYEGHWRQVCDQGWTMNNSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLT 239
Y G W VCD W N++ VVC L G+ P ++ + + + + D
Sbjct: 1128 LYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDD--------- 1178
Query: 240 NKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPH--FRPPKT 297
V C G E ++ +C P G L C A V C A P T
Sbjct: 1179 ---------VRCSGHESYLWSC-----PHNGWLSHNCGHHEDAGVICSASQSQPTPSPDT 1224
Query: 298 KPQRKGSWA---EEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGF 354
P S A +RL +G +GRVEVL WGTVCD W+ A+VVCRQLG
Sbjct: 1225 WPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGC 1284
Query: 355 GSAREALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNV-- 412
G A A AR GQG GPI L +VRC G+E L CP + C H DA V C+
Sbjct: 1285 GWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQ 1344
Query: 413 ------PNMGFQNQVRLAGG------RIPEEG-LLEVQVEVNGVPRWGSVCSENWGLTEA 459
P+ + AG R+ G + +VEV WG+VC + W +A
Sbjct: 1345 SQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDA 1404
Query: 460 MVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPV--HCSH 517
V CRQLG G+A A F G + +V+ VRCSG E L C +G + +C H
Sbjct: 1405 NVVCRQLGCGWATSAPGNARFGQG---SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 1461
Query: 518 GGGRFLAGVSCMDS 531
AGV C S
Sbjct: 1462 HED---AGVICSAS 1472
Score = 254 bits (649), Expect = 2e-67
Identities = 187/547 (34%), Positives = 244/547 (44%), Gaps = 70/547 (12%)
Query: 18 QPPPSRPQSLGTTKLRLVGPESKPE----------EGRLEVLHQGQWGTVCDDNFAIQEA 67
QP PS P + T+ G ES +GR+EVL++G WGTVCDD + +A
Sbjct: 1217 QPTPS-PDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDA 1275
Query: 68 TVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSED 127
V CRQLG A + +A++GQG GPI LD+VRC G ES L C NGW +C H ED
Sbjct: 1276 NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHED 1335
Query: 128 VGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHW 187
GVIC + + T S P + +G VEV Y G W
Sbjct: 1336 AGVICSASQSQ----PTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSW 1391
Query: 188 RQVCDQGWTMNNSRVVCGMLG--FPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFW 245
VCD W N++ VVC LG + + P ++ + + + + D
Sbjct: 1392 GTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD--------------- 1436
Query: 246 IHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPK--TKPQRKG 303
V C G E ++ +C P G L C A V C A P T P +
Sbjct: 1437 ---VRCSGHESYLWSC-----PHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRA 1488
Query: 304 SWAEEPR---VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREA 360
S A +RL +G GRVEVL WGTVCD W+ A+VVCRQLG G A A
Sbjct: 1489 STAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSA 1548
Query: 361 LFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRC---------- 410
A+ GQG GPI L +VRC G+E L CP + C H DA V C
Sbjct: 1549 PGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPR 1608
Query: 411 -------NVPNMGFQNQVRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVAC 463
N+P + ++ LA + +VEV WG+VC ++W +A V C
Sbjct: 1609 PDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVC 1668
Query: 464 RQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPV--HCSHGGGR 521
RQLG G+A+ A F G + +V+ VRCSG E L C G + +C H
Sbjct: 1669 RQLGCGWAMSAPGNARFGQG---SGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHED- 1724
Query: 522 FLAGVSC 528
AGV C
Sbjct: 1725 --AGVIC 1729
Score = 211 bits (536), Expect = 3e-54
Identities = 146/413 (35%), Positives = 184/413 (44%), Gaps = 47/413 (11%)
Query: 18 QPPPSRPQSLGTTKLRLVGPESKPE----------EGRLEVLHQGQWGTVCDDNFAIQEA 67
QP PS P + T+ G ES +GR+EVL++G WGTVCDD + +A
Sbjct: 1346 QPTPS-PDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDA 1404
Query: 68 TVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSED 127
V CRQLG A + +A++GQG GPI LD+VRC G ES L C NGW +C H ED
Sbjct: 1405 NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHED 1464
Query: 128 VGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHW 187
GVIC + + T S P R + G VEV Y+G W
Sbjct: 1465 AGVICSASQSQ----PTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSW 1520
Query: 188 RQVCDQGWTMNNSRVVCGMLG--FPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFW 245
VCD W N++ VVC LG + P ++ + + + + D
Sbjct: 1521 GTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD--------------- 1565
Query: 246 IHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPKTK------- 298
V C G E ++ +C P G L C A V C A P+
Sbjct: 1566 ---VRCSGHESYLWSC-----PHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNL 1617
Query: 299 PQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAR 358
P +RL +G GRVEVL WGTVCD W+ A+VVCRQLG G A
Sbjct: 1618 PALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1677
Query: 359 EALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCN 411
A AR GQG GPI L +VRC G E L CP + C H DA V C+
Sbjct: 1678 SAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 1730
Score = 110 bits (276), Expect = 4e-24
Identities = 50/89 (56%), Positives = 63/89 (70%)
Query: 44 GRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCV 103
GR+E+ H G WGTVCDD++ IQEA V CRQLG A++ +A +G G GPI LD+V C
Sbjct: 1887 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1946
Query: 104 GTESSLDQCGSNGWGVSDCSHSEDVGVIC 132
GTES+L QC + GW +C+H ED GVIC
Sbjct: 1947 GTESTLWQCRNRGWFSHNCNHREDAGVIC 1975
Score = 87.8 bits (216), Expect = 3e-17
Identities = 46/101 (45%), Positives = 52/101 (51%)
Query: 311 VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGL 370
V L S + GRVE+ WGTVCD W + A VVCRQLG G A AL A G G
Sbjct: 1876 VNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGS 1935
Query: 371 GPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCN 411
GPI L +V C G E TL C + C H DA V C+
Sbjct: 1936 GPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1976
Score = 68.6 bits (166), Expect = 2e-11
Identities = 40/99 (40%), Positives = 54/99 (54%), Gaps = 8/99 (8%)
Query: 432 GLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVV 491
GL +VE+ WG+VC ++W + EA V CRQLG G A+ A +F SG + +
Sbjct: 1883 GLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSG---SGPIT 1939
Query: 492 MSGVRCSGTELALQQCQRHG--PVHCSHGGGRFLAGVSC 528
+ V CSGTE L QC+ G +C+H R AGV C
Sbjct: 1940 LDDVECSGTESTLWQCRNRGWFSHNCNH---REDAGVIC 1975
Score = 39.3 bits (90), Expect = 0.014
Identities = 32/119 (26%), Positives = 42/119 (35%), Gaps = 22/119 (18%)
Query: 177 GAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLK 236
G VE+ + G W VCD WT+ + VVC LG V + Y
Sbjct: 1887 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG-------------- 1932
Query: 237 SLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPP 295
+ + V C GTE + C+ RG C A V C +G H P
Sbjct: 1933 --SGSGPITLDDVECSGTESTLWQCR-----NRGWFSHNCNHREDAGVIC-SGNHLSTP 1983
>gi|148539842 deleted in malignant brain tumors 1 isoform b
precursor [Homo sapiens]
Length = 2413
Score = 271 bits (692), Expect = 2e-72
Identities = 197/552 (35%), Positives = 259/552 (46%), Gaps = 89/552 (16%)
Query: 32 LRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQG 91
LRLV + + + GR+E+L++G WGTVCDD++ +A V CRQLG A++ +A +GQG
Sbjct: 102 LRLVNGDGRCQ-GRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQG 160
Query: 92 EGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGP 151
GPI LD+VRC G ES L C NGW +C H ED GVIC +A P
Sbjct: 161 SGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVIC--------------SAAQP 206
Query: 152 QGRRLEE---VRLKPILASAKQHSPVT----------EGAVEVKYEGHWRQVCDQGWTMN 198
Q E VR+ P + + S + G VEV Y G W VCD W N
Sbjct: 207 QSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTN 266
Query: 199 NSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEP 256
++ VVC L G+ P ++ + + + + D V C G E
Sbjct: 267 DANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD------------------VRCSGHES 308
Query: 257 HMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRP---PKTKPQRKGSWA---EEPR 310
++ +C P G L C A V C A P RP P T P S A
Sbjct: 309 YLWSC-----PHNGWLTHNCGHSEDAGVICSA-PQSRPTPSPDTWPTSHASTAGPESSLA 362
Query: 311 VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGL 370
+RL +G +GRVEVL WGTVCD W+ A+VVCRQLG G A A AR GQG
Sbjct: 363 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGS 422
Query: 371 GPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRC------NVPNMGFQNQVRLA 424
GPI L +VRC GYE L CP + CQH DA V C + P+ + L
Sbjct: 423 GPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLP 482
Query: 425 GGRIPEEGLLEVQVEVNGVPR------------WGSVCSENWGLTEAMVACRQLGLGFAI 472
+ E L +++ VNG R WG+VC ++W +A V CRQLG G+A+
Sbjct: 483 ASTVGSESSLALRL-VNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 541
Query: 473 HAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPV--HCSHGGGRFLAGVSCMD 530
A F G + +V+ VRCSG E L C +G + +C H AGV C
Sbjct: 542 LAPGNARFGQG---SGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSED---AGVIC-- 593
Query: 531 SAPDLVMNAQLV 542
S P+ + +LV
Sbjct: 594 SGPESSLALRLV 605
Score = 271 bits (692), Expect = 2e-72
Identities = 196/539 (36%), Positives = 257/539 (47%), Gaps = 66/539 (12%)
Query: 22 SRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALT 81
S P+S + LRLV + + GR+EVL++G WGTVCDD++ +A V CRQLG A +
Sbjct: 594 SGPES--SLALRLVNGGDRCQ-GRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATS 650
Query: 82 WAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGY- 140
+A++GQG GPI LD+VRC G ES L C +NGW +C H ED GVIC + R
Sbjct: 651 APGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAGVICSAAQSRSTP 710
Query: 141 LSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNS 200
+T+S P E L L + S +G VEV Y G W VCD W N++
Sbjct: 711 RPDTLSTITLPPSTVGSESSLTLRLVNG---SDRCQGRVEVLYRGSWGTVCDDSWDTNDA 767
Query: 201 RVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHM 258
VVC L G+ + P ++ + + + + D V C G E ++
Sbjct: 768 NVVCRQLGCGWATSAPGNARFGQGSGPIVLDD------------------VRCSGHESYL 809
Query: 259 ANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRP---PKTKPQRKGSWA---EEPRVR 312
+C P G L C A V C RP P T P S A +R
Sbjct: 810 WSC-----PHNGWLSHNCGHHEDAGVICSVS-QSRPTPSPDTWPTSHASTAGPESSLALR 863
Query: 313 LRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGP 372
L +G +GRVEVL WGTVCD W+ A+VVCRQLG G A A AR GQG GP
Sbjct: 864 LVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGSGP 923
Query: 373 IHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRC------NVPNMGFQNQVRLAGG 426
I L +VRC GYE L CP + CQH DA V C + P+ + L
Sbjct: 924 IVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPAS 983
Query: 427 RIPEEGLLEVQVEVNGVPR------------WGSVCSENWGLTEAMVACRQLGLGFAIHA 474
+ E L +++ VNG R WG+VC ++W +A V CRQLG G+A+ A
Sbjct: 984 TVGSESSLALRL-VNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSA 1042
Query: 475 YKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPV--HCSHGGGRFLAGVSCMDS 531
F G + +V+ VRCSG E L C +G + +C H AGV C S
Sbjct: 1043 PGNARFGQG---SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSED---AGVICSAS 1095
Score = 265 bits (678), Expect = 9e-71
Identities = 187/526 (35%), Positives = 247/526 (46%), Gaps = 61/526 (11%)
Query: 19 PPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEA 78
PP S + LRLV + GR+EVL++G WGTVCDD + +A V CRQLG
Sbjct: 221 PPVPTEGSESSLALRLVNGGDRCR-GRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGW 279
Query: 79 ALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHR 138
A++ +A++GQG GPI LD+VRC G ES L C NGW +C HSED GVIC + R
Sbjct: 280 AMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSR 339
Query: 139 GYLSETV-----SNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQ 193
S ++ GP+ + L+ + + +G VEV Y G W VCD
Sbjct: 340 PTPSPDTWPTSHASTAGPE----SSLALRLVNGGDR-----CQGRVEVLYRGSWGTVCDD 390
Query: 194 GWTMNNSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTC 251
W +++ VVC L G+ + P ++ + + + + D V C
Sbjct: 391 SWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD------------------VRC 432
Query: 252 LGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVA-------GPHFRPPKTKPQRKGS 304
G E ++ +C P G L C A V C A P P T P
Sbjct: 433 SGYESYLWSC-----PHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVG 487
Query: 305 WAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGA 364
+RL +G +GRVEVL WGTVCD W+ A+VVCRQLG G A A A
Sbjct: 488 SESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNA 547
Query: 365 RLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLA 424
R GQG GPI L +VRC G E L CP + C H DA V C+ P +RL
Sbjct: 548 RFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGPESSL--ALRLV 605
Query: 425 GGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGT 484
G +G +EV + WG+VC ++W +A V CRQLG G+A A F G
Sbjct: 606 NGGDRCQGRVEVLYRGS----WGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQG- 660
Query: 485 PRAQEVVMSGVRCSGTELALQQCQRHGPV--HCSHGGGRFLAGVSC 528
+ +V+ VRCSG E L C +G + +C H AGV C
Sbjct: 661 --SGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHED---AGVIC 701
Score = 263 bits (672), Expect = 4e-70
Identities = 193/556 (34%), Positives = 257/556 (46%), Gaps = 90/556 (16%)
Query: 2 AWSPPATLFLFLLLLGQPPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDN 61
+WS P+ L + L P S S + LRLV + + GR+EVL++G WGTVCDD+
Sbjct: 467 SWSTPSPDTLPTITL---PASTVGSESSLALRLVNGGDRCQ-GRVEVLYRGSWGTVCDDS 522
Query: 62 FAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSD 121
+ +A V CRQLG A+ +A++GQG GPI LD+VRC G ES L C NGW +
Sbjct: 523 WDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHN 582
Query: 122 CSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEV 181
C HSED GVIC GP+ + L+ + + +G VEV
Sbjct: 583 CGHSEDAGVICS----------------GPE----SSLALRLVNGGDR-----CQGRVEV 617
Query: 182 KYEGHWRQVCDQGWTMNNSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLT 239
Y G W VCD W N++ VVC L G+ + P ++ + + + + D
Sbjct: 618 LYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD--------- 668
Query: 240 NKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPK--- 296
V C G E ++ +C P G L C A V C A P+
Sbjct: 669 ---------VRCSGHESYLWSC-----PNNGWLSHNCGHHEDAGVICSAAQSRSTPRPDT 714
Query: 297 ----TKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQL 352
T P +RL +G+ +GRVEVL WGTVCD W+ A+VVCRQL
Sbjct: 715 LSTITLPPSTVGSESSLTLRLVNGSDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQL 774
Query: 353 GFGSAREALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNV 412
G G A A AR GQG GPI L +VRC G+E L CP + C H DA V C+V
Sbjct: 775 GCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSV 834
Query: 413 --------PNMGFQNQVRLAGGRIPEEGL----------LEVQVEVNGVPRWGSVCSENW 454
P+ + AG PE L + +VEV WG+VC ++W
Sbjct: 835 SQSRPTPSPDTWPTSHASTAG---PESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSW 891
Query: 455 GLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPV- 513
++A V CRQLG G+A A F G + +V+ VRCSG E L C +G +
Sbjct: 892 DTSDANVVCRQLGCGWATSAPGNARFGQG---SGPIVLDDVRCSGYESYLWSCPHNGWLS 948
Query: 514 -HCSHGGGRFLAGVSC 528
+C H AGV C
Sbjct: 949 HNCQHSED---AGVIC 961
Score = 261 bits (667), Expect = 2e-69
Identities = 196/550 (35%), Positives = 253/550 (46%), Gaps = 70/550 (12%)
Query: 18 QPPPSRPQSLGTTKLRLVGPESKPE----------EGRLEVLHQGQWGTVCDDNFAIQEA 67
+P PS P + T+ GPES +GR+EVL++G WGTVCDD++ +A
Sbjct: 838 RPTPS-PDTWPTSHASTAGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDA 896
Query: 68 TVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSED 127
V CRQLG A + +A++GQG GPI LD+VRC G ES L C NGW +C HSED
Sbjct: 897 NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSED 956
Query: 128 VGVICHPRRHRGYLS-ETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGH 186
GVIC S +T+ P E L L + +G VEV Y+G
Sbjct: 957 AGVICSAAHSWSTPSPDTLPTITLPASTVGSESSLALRLVNGGDR---CQGRVEVLYQGS 1013
Query: 187 WRQVCDQGWTMNNSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSF 244
W VCD W N++ VVC L G+ P ++ + + + + D
Sbjct: 1014 WGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDD-------------- 1059
Query: 245 WIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRP---PKTKPQR 301
V C G E ++ +C P G L C A V C A RP P T P
Sbjct: 1060 ----VRCSGHESYLWSC-----PHNGWLSHNCGHSEDAGVICSAS-QSRPTPSPDTWPTS 1109
Query: 302 KGSWA---EEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAR 358
S A +RL +G +GRVEVL WGTVCD W+ A+VVCRQLG G A
Sbjct: 1110 HASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGWAM 1169
Query: 359 EALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNV------ 412
A AR GQG GPI L +VRC G+E L CP + C H DA V C+
Sbjct: 1170 SAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQSQPT 1229
Query: 413 --PNMGFQNQVRLAGG------RIPEEG-LLEVQVEVNGVPRWGSVCSENWGLTEAMVAC 463
P+ + AG R+ G + +VEV WG+VC + W +A V C
Sbjct: 1230 PSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVC 1289
Query: 464 RQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPV--HCSHGGGR 521
RQLG G+A A F G + +V+ VRCSG E L C +G + +C H
Sbjct: 1290 RQLGCGWATSAPGNARFGQG---SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHED- 1345
Query: 522 FLAGVSCMDS 531
AGV C S
Sbjct: 1346 --AGVICSAS 1353
Score = 261 bits (667), Expect = 2e-69
Identities = 196/554 (35%), Positives = 253/554 (45%), Gaps = 61/554 (11%)
Query: 2 AWSPPATLFLFLLLLGQPPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDN 61
+WS P+ L + L P S S + LRLV + + GR+EVL+QG WGTVCDD+
Sbjct: 966 SWSTPSPDTLPTITL---PASTVGSESSLALRLVNGGDRCQ-GRVEVLYQGSWGTVCDDS 1021
Query: 62 FAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSD 121
+ +A V CRQLG A++ +A++GQG GPI LD+VRC G ES L C NGW +
Sbjct: 1022 WDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN 1081
Query: 122 CSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEV 181
C HSED GVIC + R T S P + +G VEV
Sbjct: 1082 CGHSEDAGVICSASQSR----PTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEV 1137
Query: 182 KYEGHWRQVCDQGWTMNNSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLT 239
Y G W VCD W N++ VVC L G+ P ++ + + + + D
Sbjct: 1138 LYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDD--------- 1188
Query: 240 NKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPH--FRPPKT 297
V C G E ++ +C P G L C A V C A P T
Sbjct: 1189 ---------VRCSGHESYLWSC-----PHNGWLSHNCGHHEDAGVICSASQSQPTPSPDT 1234
Query: 298 KPQRKGSWA---EEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGF 354
P S A +RL +G +GRVEVL WGTVCD W+ A+VVCRQLG
Sbjct: 1235 WPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGC 1294
Query: 355 GSAREALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNV-- 412
G A A AR GQG GPI L +VRC G+E L CP + C H DA V C+
Sbjct: 1295 GWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQ 1354
Query: 413 ------PNMGFQNQVRLAGG------RIPEEG-LLEVQVEVNGVPRWGSVCSENWGLTEA 459
P+ + AG R+ G + +VEV WG+VC + W +A
Sbjct: 1355 SQPTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDA 1414
Query: 460 MVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPV--HCSH 517
V CRQLG G+A A F G + +V+ VRCSG E L C +G + +C H
Sbjct: 1415 NVVCRQLGCGWATSAPGNARFGQG---SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 1471
Query: 518 GGGRFLAGVSCMDS 531
AGV C S
Sbjct: 1472 HED---AGVICSAS 1482
Score = 254 bits (649), Expect = 2e-67
Identities = 187/547 (34%), Positives = 244/547 (44%), Gaps = 70/547 (12%)
Query: 18 QPPPSRPQSLGTTKLRLVGPESKPE----------EGRLEVLHQGQWGTVCDDNFAIQEA 67
QP PS P + T+ G ES +GR+EVL++G WGTVCDD + +A
Sbjct: 1227 QPTPS-PDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDA 1285
Query: 68 TVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSED 127
V CRQLG A + +A++GQG GPI LD+VRC G ES L C NGW +C H ED
Sbjct: 1286 NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHED 1345
Query: 128 VGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHW 187
GVIC + + T S P + +G VEV Y G W
Sbjct: 1346 AGVICSASQSQ----PTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSW 1401
Query: 188 RQVCDQGWTMNNSRVVCGMLG--FPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFW 245
VCD W N++ VVC LG + + P ++ + + + + D
Sbjct: 1402 GTVCDDYWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD--------------- 1446
Query: 246 IHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPK--TKPQRKG 303
V C G E ++ +C P G L C A V C A P T P +
Sbjct: 1447 ---VRCSGHESYLWSC-----PHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRA 1498
Query: 304 SWAEEPR---VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREA 360
S A +RL +G GRVEVL WGTVCD W+ A+VVCRQLG G A A
Sbjct: 1499 STAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSA 1558
Query: 361 LFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRC---------- 410
A+ GQG GPI L +VRC G+E L CP + C H DA V C
Sbjct: 1559 PGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPR 1618
Query: 411 -------NVPNMGFQNQVRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVAC 463
N+P + ++ LA + +VEV WG+VC ++W +A V C
Sbjct: 1619 PDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVC 1678
Query: 464 RQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPV--HCSHGGGR 521
RQLG G+A+ A F G + +V+ VRCSG E L C G + +C H
Sbjct: 1679 RQLGCGWAMSAPGNARFGQG---SGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHED- 1734
Query: 522 FLAGVSC 528
AGV C
Sbjct: 1735 --AGVIC 1739
Score = 211 bits (536), Expect = 3e-54
Identities = 146/413 (35%), Positives = 184/413 (44%), Gaps = 47/413 (11%)
Query: 18 QPPPSRPQSLGTTKLRLVGPESKPE----------EGRLEVLHQGQWGTVCDDNFAIQEA 67
QP PS P + T+ G ES +GR+EVL++G WGTVCDD + +A
Sbjct: 1356 QPTPS-PDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDA 1414
Query: 68 TVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSED 127
V CRQLG A + +A++GQG GPI LD+VRC G ES L C NGW +C H ED
Sbjct: 1415 NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHED 1474
Query: 128 VGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHW 187
GVIC + + T S P R + G VEV Y+G W
Sbjct: 1475 AGVICSASQSQ----PTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSW 1530
Query: 188 RQVCDQGWTMNNSRVVCGMLG--FPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFW 245
VCD W N++ VVC LG + P ++ + + + + D
Sbjct: 1531 GTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD--------------- 1575
Query: 246 IHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPKTK------- 298
V C G E ++ +C P G L C A V C A P+
Sbjct: 1576 ---VRCSGHESYLWSC-----PHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNL 1627
Query: 299 PQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAR 358
P +RL +G GRVEVL WGTVCD W+ A+VVCRQLG G A
Sbjct: 1628 PALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1687
Query: 359 EALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCN 411
A AR GQG GPI L +VRC G E L CP + C H DA V C+
Sbjct: 1688 SAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 1740
Score = 110 bits (276), Expect = 4e-24
Identities = 50/89 (56%), Positives = 63/89 (70%)
Query: 44 GRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCV 103
GR+E+ H G WGTVCDD++ IQEA V CRQLG A++ +A +G G GPI LD+V C
Sbjct: 1897 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1956
Query: 104 GTESSLDQCGSNGWGVSDCSHSEDVGVIC 132
GTES+L QC + GW +C+H ED GVIC
Sbjct: 1957 GTESTLWQCRNRGWFSHNCNHREDAGVIC 1985
Score = 87.8 bits (216), Expect = 3e-17
Identities = 46/101 (45%), Positives = 52/101 (51%)
Query: 311 VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGL 370
V L S + GRVE+ WGTVCD W + A VVCRQLG G A AL A G G
Sbjct: 1886 VNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGS 1945
Query: 371 GPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCN 411
GPI L +V C G E TL C + C H DA V C+
Sbjct: 1946 GPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1986
Score = 68.6 bits (166), Expect = 2e-11
Identities = 40/99 (40%), Positives = 54/99 (54%), Gaps = 8/99 (8%)
Query: 432 GLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVV 491
GL +VE+ WG+VC ++W + EA V CRQLG G A+ A +F SG + +
Sbjct: 1893 GLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSG---SGPIT 1949
Query: 492 MSGVRCSGTELALQQCQRHG--PVHCSHGGGRFLAGVSC 528
+ V CSGTE L QC+ G +C+H R AGV C
Sbjct: 1950 LDDVECSGTESTLWQCRNRGWFSHNCNH---REDAGVIC 1985
Score = 39.3 bits (90), Expect = 0.014
Identities = 32/119 (26%), Positives = 42/119 (35%), Gaps = 22/119 (18%)
Query: 177 GAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLK 236
G VE+ + G W VCD WT+ + VVC LG V + Y
Sbjct: 1897 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG-------------- 1942
Query: 237 SLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPP 295
+ + V C GTE + C+ RG C A V C +G H P
Sbjct: 1943 --SGSGPITLDDVECSGTESTLWQCR-----NRGWFSHNCNHREDAGVIC-SGNHLSTP 1993
>gi|148539840 deleted in malignant brain tumors 1 isoform a
precursor [Homo sapiens]
Length = 1785
Score = 270 bits (689), Expect = 5e-72
Identities = 194/541 (35%), Positives = 253/541 (46%), Gaps = 87/541 (16%)
Query: 32 LRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQG 91
LRLV + + + GR+E+L++G WGTVCDD++ +A V CRQLG A++ +A +GQG
Sbjct: 102 LRLVNGDGRCQ-GRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQG 160
Query: 92 EGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGP 151
GPI LD+VRC G ES L C NGW +C H ED GVIC +A P
Sbjct: 161 SGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVIC--------------SAAQP 206
Query: 152 QGRRLEE---VRLKPILASAKQHSPVT----------EGAVEVKYEGHWRQVCDQGWTMN 198
Q E VR+ P + + S + G VEV Y G W VCD W N
Sbjct: 207 QSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTN 266
Query: 199 NSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEP 256
++ VVC L G+ P ++ + + + + D V C G E
Sbjct: 267 DANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD------------------VRCSGHES 308
Query: 257 HMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRP---PKTKPQRKGSWA---EEPR 310
++ +C P G L C A V C A P RP P T P S A
Sbjct: 309 YLWSC-----PHNGWLTHNCGHSEDAGVICSA-PQSRPTPSPDTWPTSHASTAGPESSLA 362
Query: 311 VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGL 370
+RL +G +GRVEVL WGTVCD W+ A+VVCRQLG G A A AR GQG
Sbjct: 363 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGS 422
Query: 371 GPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRC------NVPNMGFQNQVRLA 424
GPI L +VRC GYE L CP + CQH DA V C + P+ + L
Sbjct: 423 GPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLP 482
Query: 425 GGRIPEEGLLEVQVEVNGVPR------------WGSVCSENWGLTEAMVACRQLGLGFAI 472
+ E L +++ VNG R WG+VC ++W +A V CRQLG G+A+
Sbjct: 483 ASTVGSESSLALRL-VNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAM 541
Query: 473 HAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPV--HCSHGGGRFLAGVSCMD 530
A F G + +V+ VRCSG E L C +G + +C H AGV C
Sbjct: 542 SAPGNARFGQG---SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSED---AGVICSA 595
Query: 531 S 531
S
Sbjct: 596 S 596
Score = 262 bits (669), Expect = 1e-69
Identities = 195/551 (35%), Positives = 253/551 (45%), Gaps = 61/551 (11%)
Query: 2 AWSPPATLFLFLLLLGQPPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDN 61
+WS P+ L + L P S S + LRLV + + GR+EVL+QG WGTVCDD+
Sbjct: 467 SWSTPSPDTLPTITL---PASTVGSESSLALRLVNGGDRCQ-GRVEVLYQGSWGTVCDDS 522
Query: 62 FAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSD 121
+ +A V CRQLG A++ +A++GQG GPI LD+VRC G ES L C NGW +
Sbjct: 523 WDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHN 582
Query: 122 CSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEV 181
C HSED GVIC + R T S P + +G VEV
Sbjct: 583 CGHSEDAGVICSASQSR----PTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEV 638
Query: 182 KYEGHWRQVCDQGWTMNNSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLT 239
Y G W VCD W N++ VVC L G+ P ++ + + + + D
Sbjct: 639 LYRGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDD--------- 689
Query: 240 NKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPH--FRPPKT 297
V C G E ++ +C P G L C A V C A P T
Sbjct: 690 ---------VRCSGHESYLWSC-----PHNGWLSHNCGHHEDAGVICSASQSQPTPSPDT 735
Query: 298 KPQRKGSWA---EEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGF 354
P S A +RL +G +GRVEVL WGTVCD W+ A+VVCRQLG
Sbjct: 736 WPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGC 795
Query: 355 GSAREALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNV-- 412
G A A AR GQG GPI L +VRC G+E L CP + C H DA V C+
Sbjct: 796 GWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQ 855
Query: 413 ------PNMGFQNQVRLAGG------RIPEEG-LLEVQVEVNGVPRWGSVCSENWGLTEA 459
P+ ++ AG R+ G +VEV WG+VC + W +A
Sbjct: 856 SQPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDA 915
Query: 460 MVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPV--HCSH 517
V CRQLG G+A+ A F G + +V+ VRCSG E L C +G + +C H
Sbjct: 916 NVVCRQLGCGWAMSAPGNAQFGQG---SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGH 972
Query: 518 GGGRFLAGVSC 528
AGV C
Sbjct: 973 HED---AGVIC 980
Score = 259 bits (663), Expect = 5e-69
Identities = 189/544 (34%), Positives = 251/544 (46%), Gaps = 70/544 (12%)
Query: 19 PPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEA 78
PP S + LRLV + GR+EVL++G WGTVCDD + +A V CRQLG
Sbjct: 221 PPVPTEGSESSLALRLVNGGDRCR-GRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGW 279
Query: 79 ALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHR 138
A++ +A++GQG GPI LD+VRC G ES L C NGW +C HSED GVIC + R
Sbjct: 280 AMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSR 339
Query: 139 GYLSETV-----SNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQ 193
S ++ GP+ + L+ + + +G VEV Y G W VCD
Sbjct: 340 PTPSPDTWPTSHASTAGPE----SSLALRLVNGGDR-----CQGRVEVLYRGSWGTVCDD 390
Query: 194 GWTMNNSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTC 251
W +++ VVC L G+ + P ++ + + + + D V C
Sbjct: 391 SWDTSDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD------------------VRC 432
Query: 252 LGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVA-------GPHFRPPKTKPQRKGS 304
G E ++ +C P G L C A V C A P P T P
Sbjct: 433 SGYESYLWSC-----PHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVG 487
Query: 305 WAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGA 364
+RL +G +GRVEVL WGTVCD W+ A+VVCRQLG G A A A
Sbjct: 488 SESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNA 547
Query: 365 RLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNV--------PNMG 416
R GQG GPI L +VRC G+E L CP + C H DA V C+ P+
Sbjct: 548 RFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQSRPTPSPDTW 607
Query: 417 FQNQVRLAGG------RIPEEG-LLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLG 469
+ AG R+ G + +VEV WG+VC + W +A V CRQLG G
Sbjct: 608 PTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCG 667
Query: 470 FAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPV--HCSHGGGRFLAGVS 527
+A+ A F G + +V+ VRCSG E L C +G + +C H AGV
Sbjct: 668 WAMSAPGNARFGQG---SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHED---AGVI 721
Query: 528 CMDS 531
C S
Sbjct: 722 CSAS 725
Score = 254 bits (648), Expect = 3e-67
Identities = 185/538 (34%), Positives = 244/538 (45%), Gaps = 63/538 (11%)
Query: 20 PPSRPQSLGTTK---LRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGF 76
P S + G+ LRLV + + GR+EVL++G WGTVCDD + +A V CRQLG
Sbjct: 608 PTSHASTAGSESSLALRLVNGGDRCQ-GRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGC 666
Query: 77 EAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRR 136
A++ +A++GQG GPI LD+VRC G ES L C NGW +C H ED GVIC +
Sbjct: 667 GWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSASQ 726
Query: 137 HRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWT 196
+ T S P + +G VEV Y G W VCD W
Sbjct: 727 SQ----PTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWD 782
Query: 197 MNNSRVVCGMLG--FPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGT 254
N++ VVC LG + + P ++ + + + + D V C G
Sbjct: 783 TNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD------------------VRCSGH 824
Query: 255 EPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPK--TKPQRKGSWAEEPR-- 310
E ++ +C P G L C A V C A P T P + S A
Sbjct: 825 ESYLWSC-----PHNGWLSHNCGHHEDAGVICSASQSQPTPSPDTWPTSRASTAGSESTL 879
Query: 311 -VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQG 369
+RL +G GRVEVL WGTVCD W+ A+VVCRQLG G A A A+ GQG
Sbjct: 880 ALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQG 939
Query: 370 LGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRC-----------------NV 412
GPI L +VRC G+E L CP + C H DA V C N+
Sbjct: 940 SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNL 999
Query: 413 PNMGFQNQVRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAI 472
P + ++ LA + +VEV WG+VC ++W +A V CRQLG G+A+
Sbjct: 1000 PALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1059
Query: 473 HAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPV--HCSHGGGRFLAGVSC 528
A F G + +V+ VRCSG E L C G + +C H AGV C
Sbjct: 1060 SAPGNARFGQG---SGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHED---AGVIC 1111
Score = 211 bits (536), Expect = 3e-54
Identities = 146/413 (35%), Positives = 184/413 (44%), Gaps = 47/413 (11%)
Query: 18 QPPPSRPQSLGTTKLRLVGPESKPE----------EGRLEVLHQGQWGTVCDDNFAIQEA 67
QP PS P + T+ G ES +GR+EVL++G WGTVCDD + +A
Sbjct: 728 QPTPS-PDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDYWDTNDA 786
Query: 68 TVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSED 127
V CRQLG A + +A++GQG GPI LD+VRC G ES L C NGW +C H ED
Sbjct: 787 NVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHED 846
Query: 128 VGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHW 187
GVIC + + T S P R + G VEV Y+G W
Sbjct: 847 AGVICSASQSQ----PTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSW 902
Query: 188 RQVCDQGWTMNNSRVVCGMLG--FPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFW 245
VCD W N++ VVC LG + P ++ + + + + D
Sbjct: 903 GTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD--------------- 947
Query: 246 IHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPKTK------- 298
V C G E ++ +C P G L C A V C A P+
Sbjct: 948 ---VRCSGHESYLWSC-----PHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNL 999
Query: 299 PQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAR 358
P +RL +G GRVEVL WGTVCD W+ A+VVCRQLG G A
Sbjct: 1000 PALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 1059
Query: 359 EALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCN 411
A AR GQG GPI L +VRC G E L CP + C H DA V C+
Sbjct: 1060 SAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 1112
Score = 110 bits (276), Expect = 4e-24
Identities = 50/89 (56%), Positives = 63/89 (70%)
Query: 44 GRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCV 103
GR+E+ H G WGTVCDD++ IQEA V CRQLG A++ +A +G G GPI LD+V C
Sbjct: 1269 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1328
Query: 104 GTESSLDQCGSNGWGVSDCSHSEDVGVIC 132
GTES+L QC + GW +C+H ED GVIC
Sbjct: 1329 GTESTLWQCRNRGWFSHNCNHREDAGVIC 1357
Score = 87.8 bits (216), Expect = 3e-17
Identities = 46/101 (45%), Positives = 52/101 (51%)
Query: 311 VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGL 370
V L S + GRVE+ WGTVCD W + A VVCRQLG G A AL A G G
Sbjct: 1258 VNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGS 1317
Query: 371 GPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCN 411
GPI L +V C G E TL C + C H DA V C+
Sbjct: 1318 GPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1358
Score = 68.6 bits (166), Expect = 2e-11
Identities = 40/99 (40%), Positives = 54/99 (54%), Gaps = 8/99 (8%)
Query: 432 GLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVV 491
GL +VE+ WG+VC ++W + EA V CRQLG G A+ A +F SG + +
Sbjct: 1265 GLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSG---SGPIT 1321
Query: 492 MSGVRCSGTELALQQCQRHG--PVHCSHGGGRFLAGVSC 528
+ V CSGTE L QC+ G +C+H R AGV C
Sbjct: 1322 LDDVECSGTESTLWQCRNRGWFSHNCNH---REDAGVIC 1357
Score = 39.3 bits (90), Expect = 0.014
Identities = 32/119 (26%), Positives = 42/119 (35%), Gaps = 22/119 (18%)
Query: 177 GAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLK 236
G VE+ + G W VCD WT+ + VVC LG V + Y
Sbjct: 1269 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG-------------- 1314
Query: 237 SLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPP 295
+ + V C GTE + C+ RG C A V C +G H P
Sbjct: 1315 --SGSGPITLDDVECSGTESTLWQCR-----NRGWFSHNCNHREDAGVIC-SGNHLSTP 1365
>gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens]
Length = 1788
Score = 269 bits (688), Expect = 6e-72
Identities = 193/538 (35%), Positives = 252/538 (46%), Gaps = 87/538 (16%)
Query: 32 LRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQG 91
LRLV + + + GR+E+L++G WGTVCDD++ +A V CRQLG A++ +A +GQG
Sbjct: 102 LRLVNGDGRCQ-GRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQG 160
Query: 92 EGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGP 151
GPI LD+VRC G ES L C NGW +C H ED GVIC +A P
Sbjct: 161 SGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVIC--------------SAAQP 206
Query: 152 QGRRLEE---VRLKPILASAKQHSPVT----------EGAVEVKYEGHWRQVCDQGWTMN 198
Q E VR+ P + + S + G VEV Y G W VCD W N
Sbjct: 207 QSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTN 266
Query: 199 NSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEP 256
++ VVC L G+ P ++ + + + + D V C G E
Sbjct: 267 DANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD------------------VRCSGHES 308
Query: 257 HMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRP---PKTKPQRKGSWA---EEPR 310
++ +C P G L C A V C A P RP P T P S A
Sbjct: 309 YLWSC-----PHNGWLTHNCGHSEDAGVICSA-PQSRPTPSPDTWPTSHASTAGSESSLA 362
Query: 311 VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGL 370
+RL +G +GRVEVL WGTVCD W+ A+VVCRQLG G A A AR GQG
Sbjct: 363 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGS 422
Query: 371 GPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRC------NVPNMGFQNQVRLA 424
GPI L +VRC GYE L CP + CQH DA V C + P+ + L
Sbjct: 423 GPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLP 482
Query: 425 GGRIPEEGLLEVQVEVNGVPR------------WGSVCSENWGLTEAMVACRQLGLGFAI 472
+ E L +++ VNG R WG+VC ++W +A V CRQLG G+A+
Sbjct: 483 ASTVGSESSLALRL-VNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAM 541
Query: 473 HAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPV--HCSHGGGRFLAGVSC 528
A F G + +V+ VRCSG E L C +G + +C H AGV C
Sbjct: 542 LAPGNARFGQG---SGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSED---AGVIC 593
Score = 265 bits (676), Expect = 2e-70
Identities = 197/559 (35%), Positives = 262/559 (46%), Gaps = 74/559 (13%)
Query: 2 AWSPPATLFLFLLLLGQPPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDN 61
+WS P+ L + L P S S + LRLV + + GR+EVL++G WGTVCDD+
Sbjct: 467 SWSTPSPDTLPTITL---PASTVGSESSLALRLVNGGDRCQ-GRVEVLYRGSWGTVCDDS 522
Query: 62 FAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSD 121
+ +A V CRQLG A+ +A++GQG GPI LD+VRC G ES L C NGW +
Sbjct: 523 WDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHN 582
Query: 122 CSHSEDVGVICH-------PRRHRGY-LSETVSNALGPQGRRLEEVRLKPILASAKQHSP 173
C HSED GVIC P R R + S + GP+ + L+ + +
Sbjct: 583 CGHSEDAGVICSALQWLPTPIRPRSWPSSHALQTCKGPE----SSLALRLVNGGDR---- 634
Query: 174 VTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDP 231
+G VEV Y G W VCD W N++ VVC L G+ + P ++ + + + + D
Sbjct: 635 -CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD- 692
Query: 232 KSRLKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPH 291
V C G E ++ +C P G L C A V C A
Sbjct: 693 -----------------VRCSGHESYLWSC-----PNNGWLSHNCGHHEDAGVICSAAQS 730
Query: 292 FRPPK--TKPQRKGSWA---EEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISAS 346
P+ T P S A +RL +G +GRVEVL WGTVCD W+ A+
Sbjct: 731 RSTPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDAN 790
Query: 347 VVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDA 406
VVCRQLG G A A AR GQG GPI L +VRC G+E L CP + C H DA
Sbjct: 791 VVCRQLGCGWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDA 850
Query: 407 AVRCNV--------PNMGFQNQVRLAGG------RIPEEG-LLEVQVEVNGVPRWGSVCS 451
V C+ P+ ++ AG R+ G +VEV WG+VC
Sbjct: 851 GVICSASQSRPTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCD 910
Query: 452 ENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHG 511
+ W +A V CRQLG G+A+ A F G + +V+ VRCSG E L C +G
Sbjct: 911 DYWDTNDANVVCRQLGCGWAMSAPGNAQFGQG---SGPIVLDDVRCSGHESYLWSCPHNG 967
Query: 512 PV--HCSHGGGRFLAGVSC 528
+ +C H AGV C
Sbjct: 968 WLSHNCGHHED---AGVIC 983
Score = 259 bits (662), Expect = 6e-69
Identities = 189/550 (34%), Positives = 253/550 (46%), Gaps = 75/550 (13%)
Query: 19 PPPSRPQSLGTTKLRLV--GPESKPE----------EGRLEVLHQGQWGTVCDDNFAIQE 66
P P RP+S ++ GPES +GR+EVL++G WGTVCDD++ +
Sbjct: 600 PTPIRPRSWPSSHALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTND 659
Query: 67 ATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSE 126
A V CRQLG A + +A++GQG GPI LD+VRC G ES L C +NGW +C H E
Sbjct: 660 ANVVCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHE 719
Query: 127 DVGVICHPRRHRGY-LSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEG 185
D GVIC + R +T + + L+ + + +G VEV Y+G
Sbjct: 720 DAGVICSAAQSRSTPRPDTWPTSHASTAGSESSLALRLVNGGDR-----CQGRVEVLYQG 774
Query: 186 HWRQVCDQGWTMNNSRVVCGMLG--FPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNS 243
W VCD W N++ VVC LG + P ++ + + + + D
Sbjct: 775 SWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDD------------- 821
Query: 244 FWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRP---PKTKPQ 300
V C G E ++ +C P G L C A V C A RP P T P
Sbjct: 822 -----VRCSGHESYLWSC-----PHNGWLSHNCGHSEDAGVICSASQS-RPTPSPDTWPT 870
Query: 301 RKGSWAEEPR---VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSA 357
+ S A +RL +G GRVEVL WGTVCD W+ A+VVCRQLG G A
Sbjct: 871 SRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWA 930
Query: 358 REALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRC------- 410
A A+ GQG GPI L +VRC G+E L CP + C H DA V C
Sbjct: 931 MSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQS 990
Query: 411 ----------NVPNMGFQNQVRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAM 460
N+P + ++ LA + +VEV WG+VC ++W +A
Sbjct: 991 TPRPDTWLTTNLPALTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDAN 1050
Query: 461 VACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPV--HCSHG 518
V CRQLG G+A+ A F G + +V+ VRCSG E L C G + +C H
Sbjct: 1051 VVCRQLGCGWAMSAPGNARFGQG---SGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHH 1107
Query: 519 GGRFLAGVSC 528
AGV C
Sbjct: 1108 ED---AGVIC 1114
Score = 256 bits (655), Expect = 4e-68
Identities = 186/539 (34%), Positives = 242/539 (44%), Gaps = 63/539 (11%)
Query: 19 PPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEA 78
PP S + LRLV + GR+EVL++G WGTVCDD + +A V CRQLG
Sbjct: 221 PPVPTEGSESSLALRLVNGGDRCR-GRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGW 279
Query: 79 ALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHR 138
A++ +A++GQG GPI LD+VRC G ES L C NGW +C HSED GVIC + R
Sbjct: 280 AMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSR 339
Query: 139 GYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMN 198
T S P + +G VEV Y G W VCD W +
Sbjct: 340 ----PTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTS 395
Query: 199 NSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEP 256
++ VVC L G+ + P ++ + + + + D V C G E
Sbjct: 396 DANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD------------------VRCSGYES 437
Query: 257 HMANCQVQVAPARGKLRPACPGGMHAVVSCVA-------GPHFRPPKTKPQRKGSWAEEP 309
++ +C P G L C A V C A P P T P
Sbjct: 438 YLWSC-----PHNGWLSHNCQHSEDAGVICSAAHSWSTPSPDTLPTITLPASTVGSESSL 492
Query: 310 RVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQG 369
+RL +G +GRVEVL WGTVCD W+ A+VVCRQLG G A A AR GQG
Sbjct: 493 ALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQG 552
Query: 370 LGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCN--------VPNMGFQNQV 421
GPI L +VRC G E L CP + C H DA V C+ + + +
Sbjct: 553 SGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSALQWLPTPIRPRSWPSSH 612
Query: 422 RLAGGRIPEEGL----------LEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFA 471
L + PE L + +VEV WG+VC ++W +A V CRQLG G+A
Sbjct: 613 ALQTCKGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 672
Query: 472 IHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPV--HCSHGGGRFLAGVSC 528
A F G + +V+ VRCSG E L C +G + +C H AGV C
Sbjct: 673 TSAPGNARFGQG---SGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHED---AGVIC 725
Score = 216 bits (551), Expect = 5e-56
Identities = 147/404 (36%), Positives = 186/404 (46%), Gaps = 40/404 (9%)
Query: 20 PPSRPQSLGTTK---LRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGF 76
P S + G+ LRLV + + GR+EVL+QG WGTVCDD++ +A V CRQLG
Sbjct: 740 PTSHASTAGSESSLALRLVNGGDRCQ-GRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGC 798
Query: 77 EAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRR 136
A++ +A++GQG GPI LD+VRC G ES L C NGW +C HSED GVIC +
Sbjct: 799 GWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQ 858
Query: 137 HRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWT 196
R T S P R + G VEV Y+G W VCD W
Sbjct: 859 SR----PTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWD 914
Query: 197 MNNSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGT 254
N++ VVC L G+ P ++ + + + + D V C G
Sbjct: 915 TNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD------------------VRCSGH 956
Query: 255 EPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPK-------TKPQRKGSWAE 307
E ++ +C P G L C A V C A P+ P
Sbjct: 957 ESYLWSC-----PHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSES 1011
Query: 308 EPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLG 367
+RL +G GRVEVL WGTVCD W+ A+VVCRQLG G A A AR G
Sbjct: 1012 SLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFG 1071
Query: 368 QGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCN 411
QG GPI L +VRC G E L CP + C H DA V C+
Sbjct: 1072 QGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 1115
Score = 110 bits (276), Expect = 4e-24
Identities = 50/89 (56%), Positives = 63/89 (70%)
Query: 44 GRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCV 103
GR+E+ H G WGTVCDD++ IQEA V CRQLG A++ +A +G G GPI LD+V C
Sbjct: 1272 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1331
Query: 104 GTESSLDQCGSNGWGVSDCSHSEDVGVIC 132
GTES+L QC + GW +C+H ED GVIC
Sbjct: 1332 GTESTLWQCRNRGWFSHNCNHREDAGVIC 1360
Score = 87.8 bits (216), Expect = 3e-17
Identities = 46/101 (45%), Positives = 52/101 (51%)
Query: 311 VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGL 370
V L S + GRVE+ WGTVCD W + A VVCRQLG G A AL A G G
Sbjct: 1261 VNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGS 1320
Query: 371 GPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCN 411
GPI L +V C G E TL C + C H DA V C+
Sbjct: 1321 GPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1361
Score = 68.6 bits (166), Expect = 2e-11
Identities = 40/99 (40%), Positives = 54/99 (54%), Gaps = 8/99 (8%)
Query: 432 GLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVV 491
GL +VE+ WG+VC ++W + EA V CRQLG G A+ A +F SG + +
Sbjct: 1268 GLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSG---SGPIT 1324
Query: 492 MSGVRCSGTELALQQCQRHG--PVHCSHGGGRFLAGVSC 528
+ V CSGTE L QC+ G +C+H R AGV C
Sbjct: 1325 LDDVECSGTESTLWQCRNRGWFSHNCNH---REDAGVIC 1360
Score = 39.3 bits (90), Expect = 0.014
Identities = 32/119 (26%), Positives = 42/119 (35%), Gaps = 22/119 (18%)
Query: 177 GAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLK 236
G VE+ + G W VCD WT+ + VVC LG V + Y
Sbjct: 1272 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG-------------- 1317
Query: 237 SLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPP 295
+ + V C GTE + C+ RG C A V C +G H P
Sbjct: 1318 --SGSGPITLDDVECSGTESTLWQCR-----NRGWFSHNCNHREDAGVIC-SGNHLSTP 1368
>gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens]
Length = 1662
Score = 268 bits (685), Expect = 1e-71
Identities = 194/544 (35%), Positives = 256/544 (47%), Gaps = 93/544 (17%)
Query: 32 LRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQG 91
LRLV + + + GR+E+L++G WGTVCDD++ +A V CRQLG A++ +A +GQG
Sbjct: 102 LRLVNGDGRCQ-GRVEILYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNAWFGQG 160
Query: 92 EGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGP 151
GPI LD+VRC G ES L C NGW +C H ED GVIC +A P
Sbjct: 161 SGPIALDDVRCSGHESYLWSCPHNGWLSHNCGHGEDAGVIC--------------SAAQP 206
Query: 152 QGRRLEE---VRLKPILASAKQHSPVT----------EGAVEVKYEGHWRQVCDQGWTMN 198
Q E VR+ P + + S + G VEV Y G W VCD W N
Sbjct: 207 QSTLRPESWPVRISPPVPTEGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDYWDTN 266
Query: 199 NSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEP 256
++ VVC L G+ P ++ + + + + D V C G E
Sbjct: 267 DANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD------------------VRCSGHES 308
Query: 257 HMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRP---PKTKPQRKGSWA---EEPR 310
++ +C P G L C A V C A P RP P T P S A
Sbjct: 309 YLWSC-----PHNGWLTHNCGHSEDAGVICSA-PQSRPTPSPDTWPTSHASTAGSESSLA 362
Query: 311 VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGL 370
+RL +G +GRVEVL WGTVCD W+ A+VVCRQLG G A A AR GQG
Sbjct: 363 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTSDANVVCRQLGCGWATSAPGNARFGQGS 422
Query: 371 GPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRC------NVPNMGFQNQ---- 420
GPI L +VRC GYE L CP + CQH DA V C + P+ G +++
Sbjct: 423 GPIVLDDVRCSGYESYLWSCPHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGERDRTDTL 482
Query: 421 --VRLAGGRIPEEGLLEVQVEVNGVPR------------WGSVCSENWGLTEAMVACRQL 466
+ L + E L +++ VNG R WG+VC ++W +A V CRQL
Sbjct: 483 PTITLPASTVGSESSLALRL-VNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQL 541
Query: 467 GLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPV--HCSHGGGRFLA 524
G G+A+ A F G + +V+ VRCSG E L C +G + +C H A
Sbjct: 542 GCGWAMLAPGNARFGQG---SGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSED---A 595
Query: 525 GVSC 528
GV C
Sbjct: 596 GVIC 599
Score = 262 bits (669), Expect = 1e-69
Identities = 188/536 (35%), Positives = 245/536 (45%), Gaps = 62/536 (11%)
Query: 20 PPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAA 79
P S S + LRLV + + GR+EVL++G WGTVCDD++ +A V CRQLG A
Sbjct: 488 PASTVGSESSLALRLVNGGDRCQ-GRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWA 546
Query: 80 LTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRG 139
+ +A++GQG GPI LD+VRC G ES L C NGW +C HSED GVIC + R
Sbjct: 547 MLAPGNARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSR- 605
Query: 140 YLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNN 199
T P + +G VEV Y+G W VCD W N+
Sbjct: 606 ---STPRPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTND 662
Query: 200 SRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPH 257
+ VVC L G+ P ++ + + + + D V C G E +
Sbjct: 663 ANVVCRQLGCGWAMSAPGNARFGQGSGPIVLDD------------------VRCSGHESY 704
Query: 258 MANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRP---PKTKPQRKGSWAEEP---RV 311
+ +C P G L C A V C A RP P T P + S A +
Sbjct: 705 LWSC-----PHNGWLSHNCGHSEDAGVICSAS-QSRPTPSPDTWPTSRASTAGSESTLAL 758
Query: 312 RLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLG 371
RL +G GRVEVL WGTVCD W+ A+VVCRQLG G A A A+ GQG G
Sbjct: 759 RLVNGGDRCRGRVEVLYQGSWGTVCDDYWDTNDANVVCRQLGCGWAMSAPGNAQFGQGSG 818
Query: 372 PIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRC-----------------NVPN 414
PI L +VRC G+E L CP + C H DA V C N+P
Sbjct: 819 PIVLDDVRCSGHESYLWSCPHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPA 878
Query: 415 MGFQNQVRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHA 474
+ ++ LA + +VEV WG+VC ++W +A V CRQLG G+A+ A
Sbjct: 879 LTVGSESSLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSA 938
Query: 475 YKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPV--HCSHGGGRFLAGVSC 528
F G + +V+ VRCSG E L C G + +C H AGV C
Sbjct: 939 PGNARFGQG---SGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHED---AGVIC 988
Score = 256 bits (654), Expect = 5e-68
Identities = 187/545 (34%), Positives = 244/545 (44%), Gaps = 66/545 (12%)
Query: 19 PPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEA 78
PP S + LRLV + GR+EVL++G WGTVCDD + +A V CRQLG
Sbjct: 221 PPVPTEGSESSLALRLVNGGDRCR-GRVEVLYRGSWGTVCDDYWDTNDANVVCRQLGCGW 279
Query: 79 ALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHR 138
A++ +A++GQG GPI LD+VRC G ES L C NGW +C HSED GVIC + R
Sbjct: 280 AMSAPGNAQFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLTHNCGHSEDAGVICSAPQSR 339
Query: 139 GYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMN 198
T S P + +G VEV Y G W VCD W +
Sbjct: 340 ----PTPSPDTWPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTS 395
Query: 199 NSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEP 256
++ VVC L G+ + P ++ + + + + D V C G E
Sbjct: 396 DANVVCRQLGCGWATSAPGNARFGQGSGPIVLDD------------------VRCSGYES 437
Query: 257 HMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPK-------------TKPQRKG 303
++ +C P G L C A V C A + P T P
Sbjct: 438 YLWSC-----PHNGWLSHNCQHSEDAGVICSAAHSWSTPSPGERDRTDTLPTITLPASTV 492
Query: 304 SWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFG 363
+RL +G +GRVEVL WGTVCD W+ A+VVCRQLG G A A
Sbjct: 493 GSESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGN 552
Query: 364 ARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNV--------PNM 415
AR GQG GPI L +VRC G E L CP + C H DA V C+ P+
Sbjct: 553 ARFGQGSGPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSAAQSRSTPRPDT 612
Query: 416 GFQNQVRLAGG------RIPEEG-LLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGL 468
+ AG R+ G + +VEV WG+VC ++W +A V CRQLG
Sbjct: 613 WPTSHASTAGSESSLALRLVNGGDRCQGRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGC 672
Query: 469 GFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPV--HCSHGGGRFLAGV 526
G+A+ A F G + +V+ VRCSG E L C +G + +C H AGV
Sbjct: 673 GWAMSAPGNARFGQG---SGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSED---AGV 726
Query: 527 SCMDS 531
C S
Sbjct: 727 ICSAS 731
Score = 216 bits (551), Expect = 5e-56
Identities = 147/404 (36%), Positives = 186/404 (46%), Gaps = 40/404 (9%)
Query: 20 PPSRPQSLGTTK---LRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGF 76
P S + G+ LRLV + + GR+EVL+QG WGTVCDD++ +A V CRQLG
Sbjct: 614 PTSHASTAGSESSLALRLVNGGDRCQ-GRVEVLYQGSWGTVCDDSWDTNDANVVCRQLGC 672
Query: 77 EAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRR 136
A++ +A++GQG GPI LD+VRC G ES L C NGW +C HSED GVIC +
Sbjct: 673 GWAMSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPHNGWLSHNCGHSEDAGVICSASQ 732
Query: 137 HRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWT 196
R T S P R + G VEV Y+G W VCD W
Sbjct: 733 SR----PTPSPDTWPTSRASTAGSESTLALRLVNGGDRCRGRVEVLYQGSWGTVCDDYWD 788
Query: 197 MNNSRVVCGML--GFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGT 254
N++ VVC L G+ P ++ + + + + D V C G
Sbjct: 789 TNDANVVCRQLGCGWAMSAPGNAQFGQGSGPIVLDD------------------VRCSGH 830
Query: 255 EPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPK-------TKPQRKGSWAE 307
E ++ +C P G L C A V C A P+ P
Sbjct: 831 ESYLWSC-----PHNGWLSHNCGHHEDAGVICSAAQSQSTPRPDTWLTTNLPALTVGSES 885
Query: 308 EPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLG 367
+RL +G GRVEVL WGTVCD W+ A+VVCRQLG G A A AR G
Sbjct: 886 SLALRLVNGGDRCRGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMSAPGNARFG 945
Query: 368 QGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCN 411
QG GPI L +VRC G E L CP + C H DA V C+
Sbjct: 946 QGSGPIVLDDVRCSGNESYLWSCPHKGWLTHNCGHHEDAGVICS 989
Score = 110 bits (276), Expect = 4e-24
Identities = 50/89 (56%), Positives = 63/89 (70%)
Query: 44 GRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCV 103
GR+E+ H G WGTVCDD++ IQEA V CRQLG A++ +A +G G GPI LD+V C
Sbjct: 1146 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGSGPITLDDVECS 1205
Query: 104 GTESSLDQCGSNGWGVSDCSHSEDVGVIC 132
GTES+L QC + GW +C+H ED GVIC
Sbjct: 1206 GTESTLWQCRNRGWFSHNCNHREDAGVIC 1234
Score = 87.8 bits (216), Expect = 3e-17
Identities = 46/101 (45%), Positives = 52/101 (51%)
Query: 311 VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGL 370
V L S + GRVE+ WGTVCD W + A VVCRQLG G A AL A G G
Sbjct: 1135 VNLNSSYGLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSGS 1194
Query: 371 GPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCN 411
GPI L +V C G E TL C + C H DA V C+
Sbjct: 1195 GPITLDDVECSGTESTLWQCRNRGWFSHNCNHREDAGVICS 1235
Score = 68.6 bits (166), Expect = 2e-11
Identities = 40/99 (40%), Positives = 54/99 (54%), Gaps = 8/99 (8%)
Query: 432 GLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVV 491
GL +VE+ WG+VC ++W + EA V CRQLG G A+ A +F SG + +
Sbjct: 1142 GLCAGRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFGSG---SGPIT 1198
Query: 492 MSGVRCSGTELALQQCQRHG--PVHCSHGGGRFLAGVSC 528
+ V CSGTE L QC+ G +C+H R AGV C
Sbjct: 1199 LDDVECSGTESTLWQCRNRGWFSHNCNH---REDAGVIC 1234
Score = 39.3 bits (90), Expect = 0.014
Identities = 32/119 (26%), Positives = 42/119 (35%), Gaps = 22/119 (18%)
Query: 177 GAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLK 236
G VE+ + G W VCD WT+ + VVC LG V + Y
Sbjct: 1146 GRVEIYHGGTWGTVCDDSWTIQEAEVVCRQLGCGRAVSALGNAYFG-------------- 1191
Query: 237 SLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPP 295
+ + V C GTE + C+ RG C A V C +G H P
Sbjct: 1192 --SGSGPITLDDVECSGTESTLWQCR-----NRGWFSHNCNHREDAGVIC-SGNHLSTP 1242
>gi|18152779 scavenger receptor cysteine rich domain containing,
group B (4 domains) [Homo sapiens]
Length = 575
Score = 251 bits (640), Expect = 2e-66
Identities = 194/570 (34%), Positives = 250/570 (43%), Gaps = 82/570 (14%)
Query: 12 FLLLLGQPPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVAC 71
FLLLL +P L +LRLVG S+ GRLEV+H G WG+VCDD++ + +A V C
Sbjct: 38 FLLLLPLASALQPTPLPFQELRLVGGPSRCR-GRLEVMHGGSWGSVCDDDWDVVDANVVC 96
Query: 72 RQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVI 131
RQLG AL +GQG GPI LDNV C G E++L +CGS GWGV +C H EDV V+
Sbjct: 97 RQLGCGLALPVPRPLAFGQGRGPILLDNVECRGQEAALSECGSRGWGVHNCFHYEDVAVL 156
Query: 132 C------HPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEG 185
C P + S L P G+ VRL + A + +G VE+ + G
Sbjct: 157 CDEFLPTQPPTRKMLTSRAPPTTL-PNGKSEGSVRL---VGGAN----LCQGRVEILHSG 208
Query: 186 HWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFW 245
W VCD W + ++ VVC LG + + ++ +
Sbjct: 209 LWGTVCDDDWGLPDAAVVCRQLGCGAAMAATTNAFFGY----------------GTGHIL 252
Query: 246 IHQVTCLGTEPHMANCQ-----VQVAPARGKLRPACPGGMHAVVSCVAGPHFRPP---KT 297
+ V C G EP +A CQ V C G ++ + R +T
Sbjct: 253 LDNVHCEGGEPRLAACQSLGWGVHNCGHHEDAGALCAGLGPPTLTALPSSATREDWAWQT 312
Query: 298 KPQRKG---------------SWA---EEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHR 339
P G +WA + R+RL G GRVEVL WGTVCD
Sbjct: 313 DPSATGVGPQPSRETALLTTAAWAAGKKSGRLRLVGGPGPCRGRVEVLHAGGWGTVCDDD 372
Query: 340 WNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNG 399
W+ A V CR+ G G A A G G GP+ L V C G E LSDC L Q+
Sbjct: 373 WDFADARVACREAGCGPALGATGLGHFGYGRGPVLLDNVGCAGTEARLSDCFHLGWGQHN 432
Query: 400 CQHENDAAVRCNVP-NMGFQNQ------VRLAGGRIPEEGLL---------EVQVEVNGV 443
C H DA C P +G Q Q R+ R P +G L E +VE+
Sbjct: 433 CGHHEDAGALCAGPEELGLQVQQDGSETTRVPTPR-PRDGHLRLVNGAHRCEGRVELYLG 491
Query: 444 PRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELA 503
RWG+VC + W L A V CRQLG G A+ A E F P +++ V+C G E A
Sbjct: 492 QRWGTVCDDAWDLRAAGVLCRQLGCGQALAAPGEAHF---GPGRGPILLDNVKCRGEESA 548
Query: 504 LQQCQ--RHGPVHCSHGGGRFLAGVSCMDS 531
L C R +C H A V C S
Sbjct: 549 LLLCSHIRWDAHNCDHSED---ASVLCQPS 575
>gi|4506143 neurotrypsin precursor [Homo sapiens]
Length = 875
Score = 228 bits (582), Expect = 1e-59
Identities = 135/381 (35%), Positives = 177/381 (46%), Gaps = 61/381 (16%)
Query: 32 LRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQG 91
+RL G S EGR+E+ H GQWGTVCDD + +A V CRQLG H A +G+G
Sbjct: 280 IRLAGGSSV-HEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEG 338
Query: 92 EGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGP 151
GP+ LD VRC G E S++QC + WG +C H ED GV C P L++ V G
Sbjct: 339 SGPVMLDEVRCTGNELSIEQCPKSSWGEHNCGHKEDAGVSCTP------LTDGVIRLAGG 392
Query: 152 QGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPS 211
+G EG +EV Y G W VCD GWT N+ VVC LGF
Sbjct: 393 KGSH--------------------EGRLEVYYRGQWGTVCDDGWTELNTYVVCRQLGFKY 432
Query: 212 EVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGK 271
++++ + + W+ V+C G E C R
Sbjct: 433 GKQASANHFEE-----------------STGPIWLDDVSCSGKETRFLQCS-----RRQW 470
Query: 272 LRPACPGGMHAVVSCV-AGPHFRPPKTKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNR 330
R C ++C G R P VRL G EGRVEV +N
Sbjct: 471 GRHDCSHREDVSIACYPGGEGHRLSLGFP-----------VRLMDGENKKEGRVEVFING 519
Query: 331 QWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGYERTLSDC 390
QWGT+CD W A+V+CRQLG+ A A G+G GPIH+ V+C G ER+L+DC
Sbjct: 520 QWGTICDDGWTDKDAAVICRQLGYKGPARARTMAYFGEGKGPIHVDNVKCTGNERSLADC 579
Query: 391 PALEGSQNGCQHENDAAVRCN 411
+ ++ C+H DA V C+
Sbjct: 580 IKQDIGRHNCRHSEDAGVICD 600
Score = 171 bits (433), Expect = 2e-42
Identities = 145/492 (29%), Positives = 194/492 (39%), Gaps = 78/492 (15%)
Query: 43 EGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRC 102
EG +EV G WGTVC ++ +A+V C QL + G G PI+ NVRC
Sbjct: 180 EGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFSGLGLIPIYWSNVRC 239
Query: 103 VGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLK 162
G E ++ C + W C V C S + GP
Sbjct: 240 RGDEENILLCEKDIWQGGVCPQKMAAAVTC-------------SFSHGPTF--------- 277
Query: 163 PILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRK 222
PI+ A S V EG VE+ + G W VCD W ++ V+C LG K
Sbjct: 278 PIIRLAGGSS-VHEGRVELYHAGQWGTVCDDQWDDADAEVICRQLGLSG--------IAK 328
Query: 223 VWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHA 282
W S + +V C G E + C P C A
Sbjct: 329 AWHQAYFGEGS--------GPVMLDEVRCTGNELSIEQC-----PKSSWGEHNCGHKEDA 375
Query: 283 VVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNL 342
VSC P G +RL G EGR+EV QWGTVCD W
Sbjct: 376 GVSCT-----------PLTDGV------IRLAGGKGSHEGRLEVYYRGQWGTVCDDGWTE 418
Query: 343 ISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQH 402
++ VVCRQLGF ++A + GPI L +V C G E C + ++ C H
Sbjct: 419 LNTYVVCRQLGFKYGKQASAN-HFEESTGPIWLDDVSCSGKETRFLQCSRRQWGRHDCSH 477
Query: 403 ENDAAVRCNVPNMGFQNQ----VRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTE 458
D ++ C G + VRL G +EG V+V +NG +WG++C + W +
Sbjct: 478 REDVSIACYPGGEGHRLSLGFPVRLMDGENKKEG--RVEVFING--QWGTICDDGWTDKD 533
Query: 459 AMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQC--QRHGPVHCS 516
A V CRQLG A +F G + + V+C+G E +L C Q G +C
Sbjct: 534 AAVICRQLGYKGPARARTMAYFGEG---KGPIHVDNVKCTGNERSLADCIKQDIGRHNCR 590
Query: 517 HGGGRFLAGVSC 528
H AGV C
Sbjct: 591 HSED---AGVIC 599
Score = 130 bits (328), Expect = 3e-30
Identities = 86/223 (38%), Positives = 116/223 (52%), Gaps = 18/223 (8%)
Query: 311 VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQL---GFGSAREALFGARLG 367
VRLR G EG VEV + WGTVC W+ ASV+C QL G G A++ F G
Sbjct: 170 VRLRGGKNEFEGTVEVYASGVWGTVCSSHWDDSDASVICHQLQLGGKGIAKQTPFS---G 226
Query: 368 QGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGR 427
GL PI+ S VRCRG E + C C + AAV C+ + +RLAGG
Sbjct: 227 LGLIPIYWSNVRCRGDEENILLCEKDIWQGGVCPQKMAAAVTCSFSHGPTFPIIRLAGGS 286
Query: 428 IPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRA 487
EG +VE+ +WG+VC + W +A V CRQLGL A+ + +F G +
Sbjct: 287 SVHEG----RVELYHAGQWGTVCDDQWDDADAEVICRQLGLSGIAKAWHQAYFGEG---S 339
Query: 488 QEVVMSGVRCSGTELALQQCQRH--GPVHCSHGGGRFLAGVSC 528
V++ VRC+G EL+++QC + G +C H + AGVSC
Sbjct: 340 GPVMLDEVRCTGNELSIEQCPKSSWGEHNCGH---KEDAGVSC 379
>gi|20149540 lysyl oxidase preproprotein [Homo sapiens]
Length = 417
Score = 221 bits (564), Expect = 1e-57
Identities = 108/218 (49%), Positives = 140/218 (64%), Gaps = 6/218 (2%)
Query: 519 GGRFLAGVSC---MDSAPDLVMNAQLVQETAYLEDRPLSQLYCAHEENCLSKSADHMDW- 574
GGR+ G PDLV + +Q + Y++ + L CA EENCL+ +A D
Sbjct: 196 GGRYRPGYGTGYFQYGLPDLVADPYYIQASTYVQKMSMYNLRCAAEENCLASTAYRADVR 255
Query: 575 PYGYRRLLRFSTQIYNLGRTDFRPKTGRDSWVWHQCHRHYHSIEVFTHYDLLTLNGSK-V 633
Y +R LLRF ++ N G +DF P R SW WH CH+HYHS++ F+HYDLL N + V
Sbjct: 256 DYDHRVLLRFPQRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDANTQRRV 315
Query: 634 AEGHKASFCLEDTNCPTGLQRRYACANFGEQGVTVGCWDTYRHDIDCQWVDITDVGPGNY 693
AEGHKASFCLEDT+C G RR+AC QG++ GC+DTY DIDCQW+DITDV PGNY
Sbjct: 316 AEGHKASFCLEDTSCDYGYHRRFACTAH-TQGLSPGCYDTYGADIDCQWIDITDVKPGNY 374
Query: 694 IFQVIVNPHYEVAESDFSNNMLQCRCKYDGHRVWLHNC 731
I +V VNP Y V ESD++NN+++C +Y GH + C
Sbjct: 375 ILKVSVNPSYLVPESDYTNNVVRCDIRYTGHHAYASGC 412
>gi|50659091 scavenger receptor cysteine-rich type 1 precursor [Homo
sapiens]
Length = 1453
Score = 220 bits (561), Expect = 3e-57
Identities = 152/504 (30%), Positives = 217/504 (43%), Gaps = 80/504 (15%)
Query: 31 KLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQ 90
+LRLV + P G +EV QGQWGTVCDD + +TV C+QLG + +
Sbjct: 47 ELRLVNGDG-PCSGTVEVKFQGQWGTVCDDGWNTTASTVVCKQLGCPFSFAMFRFGQAVT 105
Query: 91 GEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALG 150
G IWLD+V C G ES+L +C WG +C H EDVGV C+ + G +N+
Sbjct: 106 RHGKIWLDDVSCYGNESALWECQHREWGSHNCYHGEDVGVNCYGEANLGLRLVDGNNSCS 165
Query: 151 PQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFP 210
G VEVK++ W +CD GW +N + VVC LG P
Sbjct: 166 --------------------------GRVEVKFQERWGTICDDGWNLNTAAVVCRQLGCP 199
Query: 211 SEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARG 270
S + S W+ + C G E + NC+ RG
Sbjct: 200 SSFI----------------SSGVVNSPAVLRPIWLDDILCQGNELALWNCR-----HRG 238
Query: 271 KLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNR 330
C ++C + + +RL G GRVE+ +
Sbjct: 239 WGNHDCSHNEDVTLTCYD-----------------SSDLELRLVGGTNRCMGRVELKIQG 281
Query: 331 QWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGYERTLSDC 390
+WGTVC H+WN +A VVC+QLG G+A L G + L V C G E L DC
Sbjct: 282 RWGTVCHHKWNNAAADVVCKQLGCGTALHFAGLPHLQSGSDVVWLDGVSCSGNESFLWDC 341
Query: 391 PALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEGLLEVQVEVNGVPRWGSVC 450
C H+ND +V C + G ++RLA G G +EV++ +W ++C
Sbjct: 342 RHSGTVNFDCLHQNDVSVIC---SDGADLELRLADGSNNCSGRVEVRIH----EQWWTIC 394
Query: 451 SENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRH 510
+NW +A+V C+QLG F++ + + A+++ ++ + C+G E AL C
Sbjct: 395 DQNWKNEQALVVCKQLGCPFSVFGSRRA---KPSNEARDIWINSISCTGNESALWDCTYD 451
Query: 511 GPVH--CSHGGGRFLAGVSCMDSA 532
G C R AGV C D A
Sbjct: 452 GKAKRTCFR---RSDAGVICSDKA 472
Score = 201 bits (511), Expect = 2e-51
Identities = 130/381 (34%), Positives = 170/381 (44%), Gaps = 69/381 (18%)
Query: 31 KLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQ 90
+LRLV +S+ GR+E+ H G WGT+CDD + + +A V C++LG A SA +G+
Sbjct: 1035 RLRLVDGDSRCA-GRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGE 1093
Query: 91 GEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALG 150
G GPIWLD++ C G ES L QC S GWG DC H ED GVIC SET + +
Sbjct: 1094 GSGPIWLDDLNCTGMESHLWQCPSRGWGQHDCRHKEDAGVICSEFTALRLYSETETESCA 1153
Query: 151 PQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFP 210
G +EV Y G W V + T + +VC LG
Sbjct: 1154 --------------------------GRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCG 1187
Query: 211 SEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARG 270
V K T W+ + C T H++ Q AP
Sbjct: 1188 ENGVVSLAPLSK----------------TGSGFMWVDDIQCPKT--HISIWQCLSAPWER 1229
Query: 271 KLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNR 330
++ + P + E R+R+R G GRVE+
Sbjct: 1230 RI------------------------SSPAEETWITCEDRIRVRGGDTECSGRVEIWHAG 1265
Query: 331 QWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGYERTLSDC 390
WGTVCD W+L A VVC+QLG GSA AL A GQG G I L ++RC+G E L DC
Sbjct: 1266 SWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGTGTIWLDDMRCKGNESFLWDC 1325
Query: 391 PALEGSQNGCQHENDAAVRCN 411
A Q+ C H+ DA VRC+
Sbjct: 1326 HAKPWGQSDCGHKEDAGVRCS 1346
Score = 195 bits (495), Expect = 1e-49
Identities = 156/493 (31%), Positives = 216/493 (43%), Gaps = 83/493 (16%)
Query: 29 TTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKY 88
T LRLVG ++ GRLEV QG+WGTVCDD + + A V C QL +++
Sbjct: 580 TWGLRLVGGSNRCS-GRLEVYFQGRWGTVCDDGWNSKAAAVVCSQLDCPSSIIGMGLGNA 638
Query: 89 GQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNA 148
G G IWLD+V C G ES L C ++GWG +DCSHSEDVGVIC S+A
Sbjct: 639 STGYGKIWLDDVSCDGDESDLWSCRNSGWGNNDCSHSEDVGVIC-------------SDA 685
Query: 149 LGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLG 208
++ L+ + S++ G VEV +G +C GW MN + VVC L
Sbjct: 686 --------SDMELRLVGGSSR-----CAGKVEVNVQGAVGILCANGWGMNIAEVVCRQLE 732
Query: 209 FPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPA 268
S + V R+P ++L + C G E + +C
Sbjct: 733 CGSAIRVS------------REPHFTERTL----HILMSNSGCTGGEASLWDC------I 770
Query: 269 RGKLR-PACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRSGAQVGEGRVEVL 327
R + + AC M A + C A H +P RL GRVEV
Sbjct: 771 RWEWKQTACHLNMEASLICSA--HRQP-----------------RLVGADMPCSGRVEVK 811
Query: 328 MNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGYERTL 387
W +VCD ++L +A+V+CR+L G A G G+G G + +C G E L
Sbjct: 812 HADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGNGLTWAEKFQCEGSETHL 871
Query: 388 SDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEGLLEVQVEVNGVPRWG 447
+ CP ++ ++ C H + V C+ VRL G+ +G QVE+N + WG
Sbjct: 872 ALCPIVQHPEDTCIHSREVGVVCS-----RYTDVRLVNGKSQCDG----QVEINVLGHWG 922
Query: 448 SVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQC 507
S+C +W +A V CRQL G A+ + R+ V C G E L C
Sbjct: 923 SLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIGE---RSVRVWGHRFHCLGNESLLDNC 979
Query: 508 QRH--GPVHCSHG 518
Q G C HG
Sbjct: 980 QMTVLGAPPCIHG 992
Score = 192 bits (489), Expect = 7e-49
Identities = 146/491 (29%), Positives = 211/491 (42%), Gaps = 80/491 (16%)
Query: 33 RLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGE 92
RLVG + P GR+EV H W +VCD +F++ A V CR+L A++ + +G+G
Sbjct: 796 RLVGADM-PCSGRVEVKHADTWRSVCDSDFSLHAANVLCRELNCGDAISLSVGDHFGKGN 854
Query: 93 GPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGPQ 152
G W + +C G+E+ L C C HS +VGV+C
Sbjct: 855 GLTWAEKFQCEGSETHLALCPIVQHPEDTCIHSREVGVVCS------------------- 895
Query: 153 GRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSE 212
R +VRL + K +G VE+ GHW +CD W ++RV+C L +
Sbjct: 896 --RYTDVRL----VNGKSQC---DGQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTA 946
Query: 213 VPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKL 272
+ Y + + +R W H+ CLG E + NCQ+ V A
Sbjct: 947 LSTTGGKY--IGERSVR--------------VWGHRFHCLGNESLLDNCQMTVLGA---- 986
Query: 273 RPACPGGMHAVVSCVAG---------PHFRPPKTKPQRKGS---WAEEPRVRLRSGAQVG 320
P C G V C + P +GS E+ R+RL G
Sbjct: 987 -PPCIHGNTVSVICTGSLTQPLFPCLANVSDPYLSAVPEGSALICLEDKRLRLVDGDSRC 1045
Query: 321 EGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRC 380
GRVE+ + WGT+CD W+L A VVC++LG G A A A G+G GPI L ++ C
Sbjct: 1046 AGRVEIYHDGFWGTICDDGWDLSDAHVVCQKLGCGVAFNATVSAHFGEGSGPIWLDDLNC 1105
Query: 381 RGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEGLLEVQVEV 440
G E L CP+ Q+ C+H+ DA V C+ +RL E ++V
Sbjct: 1106 TGMESHLWQCPSRGWGQHDCRHKEDAGVICSE-----FTALRLYSETETESCAGRLEVFY 1160
Query: 441 NGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQE----VVMSGVR 496
NG WGSV N A + CRQLG G E S P ++ + + ++
Sbjct: 1161 NGT--WGSVGRRNITTAIAGIVCRQLGCG-------ENGVVSLAPLSKTGSGFMWVDDIQ 1211
Query: 497 CSGTELALQQC 507
C T +++ QC
Sbjct: 1212 CPKTHISIWQC 1222
Score = 189 bits (480), Expect = 8e-48
Identities = 156/513 (30%), Positives = 200/513 (38%), Gaps = 98/513 (19%)
Query: 31 KLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQ 90
+LRLVG ++ GR+E+ QG+WGTVC + A V C+QLG AL +A
Sbjct: 261 ELRLVGGTNRCM-GRVELKIQGRWGTVCHHKWNNAAADVVCKQLGCGTALHFAGLPHLQS 319
Query: 91 GEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALG 150
G +WLD V C G ES L C +G DC H DV VIC
Sbjct: 320 GSDVVWLDGVSCSGNESFLWDCRHSGTVNFDCLHQNDVSVICS----------------- 362
Query: 151 PQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFP 210
G LE +RL S G VEV+ W +CDQ W + VVC LG P
Sbjct: 363 -DGADLE-LRLA-------DGSNNCSGRVEVRIHEQWWTICDQNWKNEQALVVCKQLGCP 413
Query: 211 SEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARG 270
V R K WI+ ++C G E + +C G
Sbjct: 414 FSV----------------FGSRRAKPSNEARDIWINSISCTGNESALWDCTYD-----G 452
Query: 271 KLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNR 330
K + C A V C S + +RL GR+EV
Sbjct: 453 KAKRTCFRRSDAGVIC-----------------SDKADLDLRLVGAHSPCYGRLEVKYQG 495
Query: 331 QWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGYERTLSDC 390
+WGTVC RW+ +A+VVC+QLG G + GPI L +V C G E + DC
Sbjct: 496 EWGTVCHDRWSTRNAAVVCKQLGCGKPMHVFGMTYFKEASGPIWLDDVSCIGNESNIWDC 555
Query: 391 PALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEGLLEVQVEVNGVPRWGSVC 450
++ C H D V C+ +RL GG G LEV + RWG+VC
Sbjct: 556 EHSGWGKHNCVHREDVIVTCSGDATW---GLRLVGGSNRCSGRLEVYFQ----GRWGTVC 608
Query: 451 SENWGLTEAMVACRQL---------GLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTE 501
+ W A V C QL GLG A Y + W + V C G E
Sbjct: 609 DDGWNSKAAAVVCSQLDCPSSIIGMGLGNASTGYGKIW------------LDDVSCDGDE 656
Query: 502 LALQQCQRH--GPVHCSHGGGRFLAGVSCMDSA 532
L C+ G CSH GV C D++
Sbjct: 657 SDLWSCRNSGWGNNDCSHSED---VGVICSDAS 686
Score = 167 bits (423), Expect = 3e-41
Identities = 137/518 (26%), Positives = 213/518 (41%), Gaps = 89/518 (17%)
Query: 30 TKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYG 89
T +RLV +S+ + G++E+ G WG++CD ++ ++A V CRQL AL+ G
Sbjct: 898 TDVRLVNGKSQCD-GQVEINVLGHWGSLCDTHWDPEDARVLCRQLSCGTALSTTGGKYIG 956
Query: 90 QGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNAL 149
+ +W C+G ES LD C G C H V VIC G L++ + L
Sbjct: 957 ERSVRVWGHRFHCLGNESLLDNCQMTVLGAPPCIHGNTVSVIC-----TGSLTQPLFPCL 1011
Query: 150 G----------PQGRRL---EEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWT 196
P+G L E+ RL+ + ++ G VE+ ++G W +CD GW
Sbjct: 1012 ANVSDPYLSAVPEGSALICLEDKRLRLVDGDSR-----CAGRVEIYHDGFWGTICDDGWD 1066
Query: 197 MNNSRVVCGMLG--FPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGT 254
++++ VVC LG V +H+ W+ + C G
Sbjct: 1067 LSDAHVVCQKLGCGVAFNATVSAHFGE------------------GSGPIWLDDLNCTGM 1108
Query: 255 EPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLR 314
E H+ C P+RG + C A V C +E +RL
Sbjct: 1109 ESHLWQC-----PSRGWGQHDCRHKEDAGVIC-------------------SEFTALRLY 1144
Query: 315 SGAQVGE--GRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGP 372
S + GR+EV N WG+V A +VCRQLG G G G
Sbjct: 1145 SETETESCAGRLEVFYNGTWGSVGRRNITTAIAGIVCRQLGCGENGVVSLAPLSKTGSGF 1204
Query: 373 IHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEG 432
+ + +++C ++ C + + + + C ++++R+ GG G
Sbjct: 1205 MWVDDIQCPKTHISIWQCLSAPWERRISSPAEETWITC-------EDRIRVRGGDTECSG 1257
Query: 433 LLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVM 492
+VE+ WG+VC ++W L EA V C+QLG G A+ A ++ F GT + +
Sbjct: 1258 ----RVEIWHAGSWGTVCDDSWDLAEAEVVCQQLGCGSALAALRDASFGQGT---GTIWL 1310
Query: 493 SGVRCSGTELALQQCQRH--GPVHCSHGGGRFLAGVSC 528
+RC G E L C G C H + AGV C
Sbjct: 1311 DDMRCKGNESFLWDCHAKPWGQSDCGH---KEDAGVRC 1345
>gi|67782346 lysyl oxidase-like 1 preproprotein [Homo sapiens]
Length = 574
Score = 214 bits (546), Expect = 2e-55
Identities = 121/258 (46%), Positives = 149/258 (57%), Gaps = 19/258 (7%)
Query: 483 GTPRAQEVVMSGVRCSGTEL-------ALQQCQRHGPVHCSHGGGRFLAGVSCMDSAPDL 535
G PRA E VR S T A Q G V+ + GR L PDL
Sbjct: 322 GPPRALEPPYLPVRSSDTPPPGGERNGAQQGRLSVGSVYRPNQNGRGL---------PDL 372
Query: 536 VMNAQLVQETAYLEDRPLSQLYCAHEENCLSKSADHMD-WPYGYRRLLRFSTQIYNLGRT 594
V + VQ + Y++ L L CA EE CL+ +A + Y R LLRF ++ N G
Sbjct: 373 VPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYAPEATDYDVRVLLRFPQRVKNQGTA 432
Query: 595 DFRPKTGRDSWVWHQCHRHYHSIEVFTHYDLL-TLNGSKVAEGHKASFCLEDTNCPTGLQ 653
DF P R +W WH CH+HYHS++ F+HYDLL G KVAEGHKASFCLED+ C G
Sbjct: 433 DFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDAATGKKVAEGHKASFCLEDSTCDFGNL 492
Query: 654 RRYACANFGEQGVTVGCWDTYRHDIDCQWVDITDVGPGNYIFQVIVNPHYEVAESDFSNN 713
+RYAC + QG++ GC+DTY DIDCQW+DITDV PGNYI +V VNP Y V ESDF+NN
Sbjct: 493 KRYACTSH-TQGLSPGCYDTYNADIDCQWIDITDVQPGNYILKVHVNPKYIVLESDFTNN 551
Query: 714 MLQCRCKYDGHRVWLHNC 731
+++C Y G V NC
Sbjct: 552 VVRCNIHYTGRYVSATNC 569
>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
Length = 1573
Score = 213 bits (543), Expect = 4e-55
Identities = 171/583 (29%), Positives = 231/583 (39%), Gaps = 144/583 (24%)
Query: 44 GRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCV 103
GRLEV H G+WGTVCDD + +++A VACRQLG AL A +G+G GP+WL + C
Sbjct: 31 GRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGEGAGPVWLSELACR 90
Query: 104 GTESSLDQCGSNGWGVSDCSHSEDVGVICHPRR----------------HRGYLSE---- 143
G E L C GW CSH ED GV+C +R G L E
Sbjct: 91 GNEGQLGLCHHRGWKAHICSHEEDAGVVCAGQRVANSRDDSTSPLDGAPWPGLLLELSPS 150
Query: 144 ----TVSNALGPQGRRLEEVRLK---PILASAKQHSPVTEGA------------------ 178
V++A P G R K P A + + +T GA
Sbjct: 151 TEEPLVTHAPRPAGNPQNASRKKSPRPKQAKSTRAPLLTTGAPRQERLRLVSGPHRCAGR 210
Query: 179 VEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLKSL 238
+EV + G W VCD GW + ++ V C LG + +
Sbjct: 211 LEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAA----------------PGGARFG 254
Query: 239 TNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPKTK 298
W+ V C G E + +C P R C A + C GP
Sbjct: 255 PGAGPVWMDDVGCGGGEQALRDC-----PRSPWGRSNCDHSEDAGLVC-TGP-------- 300
Query: 299 PQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAR 358
PR+RL G GR+EV +WG+VCD W+L A+V CR+LG G A
Sbjct: 301 ---------APRLRLADGPHGCAGRLEVWHGGRWGSVCDDAWDLRDAAVACRELGCGGAL 351
Query: 359 EALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGF- 417
A GA G+G GPI L ++RCRG E L CPA Q+ C H DA C+ +G+
Sbjct: 352 AAPGGAFFGEGSGPIILDDLRCRGNETALRFCPARPWGQHDCHHREDAGAVCDGMPLGYV 411
Query: 418 ---------QNQVRLAGGRI----------------------------PEEGLLEV---- 436
+ R A R PE G ++
Sbjct: 412 PPTAPTDSNNSTPREAASRPPSTMTSQAPGTAGVSPPPASPTVLWEPGPEAGSPQLRLVA 471
Query: 437 -------QVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKET--WFWSGTPRA 487
++EV RWG+VC ++W + ++ V CR+LG G + W P
Sbjct: 472 GPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAAGRFGWGAGP-- 529
Query: 488 QEVVMSGVRCSGTELALQQCQR--HGPVHCSHGGGRFLAGVSC 528
+ + V C GTE +L C G +C+H GV+C
Sbjct: 530 --IWLDDVGCVGTEASLSDCPAAPWGKHNCAHNED---VGVTC 567
Score = 199 bits (505), Expect = 1e-50
Identities = 138/410 (33%), Positives = 189/410 (46%), Gaps = 63/410 (15%)
Query: 31 KLRLV-GPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYG 89
+LRLV GP GRLEV H G+WGTVCDD + +++A VACR+LG AL A++G
Sbjct: 197 RLRLVSGPHRCA--GRLEVWHGGRWGTVCDDGWDLRDAAVACRELGCGGALAAPGGARFG 254
Query: 90 QGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNAL 149
G GP+W+D+V C G E +L C + WG S+C HSED G++C R L++
Sbjct: 255 PGAGPVWMDDVGCGGGEQALRDCPRSPWGRSNCDHSEDAGLVCTGPAPRLRLAD------ 308
Query: 150 GPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGF 209
GP G G +EV + G W VCD W + ++ V C LG
Sbjct: 309 GPHG---------------------CAGRLEVWHGGRWGSVCDDAWDLRDAAVACRELGC 347
Query: 210 PSEVPVDSHYYRK-------VWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANC- 261
+ + + DL+ R ++ L+ + W Q C E A C
Sbjct: 348 GGALAAPGGAFFGEGSGPIILDDLRCRGNETALRFCPARP--W-GQHDCHHREDAGAVCD 404
Query: 262 --------------QVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPKTKPQ---RKGS 304
P RP P M + AG PP P G
Sbjct: 405 GMPLGYVPPTAPTDSNNSTPREAASRP--PSTMTSQAPGTAG--VSPPPASPTVLWEPGP 460
Query: 305 WAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGA 364
A P++RL +G GR+EV +++WGTVCD W++ ++VVCR+LG G ++ A
Sbjct: 461 EAGSPQLRLVAGPSKCSGRLEVWHDQRWGTVCDDSWDMRDSAVVCRELGCGGPQQPDPAA 520
Query: 365 -RLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVP 413
R G G GPI L +V C G E +LSDCPA ++ C H D V C P
Sbjct: 521 GRFGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGVTCTGP 570
Score = 175 bits (444), Expect = 1e-43
Identities = 134/427 (31%), Positives = 189/427 (44%), Gaps = 37/427 (8%)
Query: 19 PPPSRPQSL-------GTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVAC 71
PPP+ P L G+ +LRLV SK GRLEV H +WGTVCDD++ ++++ V C
Sbjct: 447 PPPASPTVLWEPGPEAGSPQLRLVAGPSKCS-GRLEVWHDQRWGTVCDDSWDMRDSAVVC 505
Query: 72 RQLGFEAALTWAHSA-KYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGV 130
R+LG +A ++G G GPIWLD+V CVGTE+SL C + WG +C+H+EDVGV
Sbjct: 506 RELGCGGPQQPDPAAGRFGWGAGPIWLDDVGCVGTEASLSDCPAAPWGKHNCAHNEDVGV 565
Query: 131 ICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVE---VKYEGHW 187
C +S+ S + P R + L LA+ K + VT +E K G
Sbjct: 566 TCTGPPGLDSISDPFSWSWIPGLGRDRDAWLPGELAT-KPSASVTASVLEKTTTKAPGKM 624
Query: 188 RQVCDQGWTMNNSRVVCGMLGFP------SEVPVD--SHYYRKVWDLKMRDPKSRL--KS 237
+ + T N R P ++ P D S + R P S +
Sbjct: 625 PKSTKKWVTKNAKRPTTQPPVMPTTKHSRAQSPPDLTSQTTAALTTEASRRPTSEFTRRP 684
Query: 238 LTNKNSFWIHQVTCLGTEP---HMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRP 294
T W T T + + +G + ++ P
Sbjct: 685 TTEAPQRWTSHTTATLTPQAPRERTTKTMAMLTTQGPQEMTSESTIKSIPQASLEPSAEI 744
Query: 295 PKTKPQRKGSWAEEP-----------RVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLI 343
P+ P+ A P RVRL G GR+EV +WGTVCD W+L
Sbjct: 745 PEGSPESPKDPAPSPSVSTTGESGLFRVRLADGPNRCAGRLEVWHAGRWGTVCDDNWDLR 804
Query: 344 SASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHE 403
A+V C +LG G R + G G GPI L ++ C+G E +LSDCP+ ++ C HE
Sbjct: 805 DATVACWELGCGKVRPRVGKTHYGPGTGPIWLDDMGCKGSEASLSDCPSGAWGKHNCDHE 864
Query: 404 NDAAVRC 410
D + C
Sbjct: 865 EDVGLTC 871
Score = 90.9 bits (224), Expect = 4e-18
Identities = 48/101 (47%), Positives = 57/101 (56%)
Query: 310 RVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQG 369
R+RL G GR+EV +WGTVCD W+L A+V CRQLG G A A GA G+G
Sbjct: 19 RLRLADGPHGCAGRLEVWHGGRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAFFGEG 78
Query: 370 LGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRC 410
GP+ LSE+ CRG E L C + C HE DA V C
Sbjct: 79 AGPVWLSELACRGNEGQLGLCHHRGWKAHICSHEEDAGVVC 119
Score = 57.0 bits (136), Expect = 6e-08
Identities = 46/111 (41%), Positives = 56/111 (50%), Gaps = 12/111 (10%)
Query: 420 QVRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETW 479
++RLA G G LEV +G RWG+VC + W L +A VACRQLG G A+ A +
Sbjct: 19 RLRLADGPHGCAGRLEVW---HG-GRWGTVCDDGWDLRDAAVACRQLGCGGALAAPGGAF 74
Query: 480 FWSGTPRAQEVVMSGVRCSGTELALQQCQRHG-PVH-CSHGGGRFLAGVSC 528
F G A V +S + C G E L C G H CSH AGV C
Sbjct: 75 FGEG---AGPVWLSELACRGNEGQLGLCHHRGWKAHICSHEED---AGVVC 119
Score = 52.8 bits (125), Expect = 1e-06
Identities = 41/131 (31%), Positives = 58/131 (44%), Gaps = 11/131 (8%)
Query: 391 PALEGSQNGCQHENDAAVRCNVPNMGFQN--QVRLAGGRIPEEGLLEVQVEVNGVPRWGS 448
P+ E + + D A +V G +VRLA G G LEV RWG+
Sbjct: 740 PSAEIPEGSPESPKDPAPSPSVSTTGESGLFRVRLADGPNRCAGRLEVW----HAGRWGT 795
Query: 449 VCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQ 508
VC +NW L +A VAC +LG G +T + GT + + + C G+E +L C
Sbjct: 796 VCDDNWDLRDATVACWELGCGKVRPRVGKTHYGPGT---GPIWLDDMGCKGSEASLSDCP 852
Query: 509 --RHGPVHCSH 517
G +C H
Sbjct: 853 SGAWGKHNCDH 863
>gi|44889963 CD163 antigen isoform b [Homo sapiens]
Length = 1121
Score = 213 bits (542), Expect = 5e-55
Identities = 147/466 (31%), Positives = 200/466 (42%), Gaps = 80/466 (17%)
Query: 44 GRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCV 103
GR+E+ QG+WGTVCDDNF I A+V CRQL +A++++ S+ +G+G GPIW D++ C
Sbjct: 170 GRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICN 229
Query: 104 GTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKP 163
G ES+L C GWG +C H+ED GVIC K
Sbjct: 230 GNESALWNCKHQGWGKHNCDHAEDAGVICS----------------------------KG 261
Query: 164 ILASAKQHSPVTE--GAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYR 221
S + VTE G +EV+++G W +CD GW ++ V C LG P+ V
Sbjct: 262 ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIG---- 317
Query: 222 KVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMH 281
R+ + W+ V+C G EP + C+ GK C
Sbjct: 318 ------------RVNASKGFGHIWLDSVSCQGHEPAVWQCKHH---EWGK--HYCNHNED 360
Query: 282 AVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWN 341
A V+C G + +RLR G G VEV + R G VCD W
Sbjct: 361 AGVTCSDG-----------------SDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWG 403
Query: 342 LISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQ 401
L A VVCRQLG GSA + + L C G E +L DC + C
Sbjct: 404 LKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCD 463
Query: 402 HENDAAVRCNVPNMGFQNQVRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMV 461
H +A + C+ + RL GG IP G +VEV WGS+C ++ L A V
Sbjct: 464 HYEEAKITCSA-----HREPRLVGGDIPCSG----RVEVKHGDTWGSICDSDFSLEAASV 514
Query: 462 ACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQC 507
CR+L G + F G ++ +C G E L C
Sbjct: 515 LCRELQCGTVVSILGGAHFGEGN---GQIWAEEFQCEGHESHLSLC 557
Score = 207 bits (527), Expect = 3e-53
Identities = 130/392 (33%), Positives = 177/392 (45%), Gaps = 69/392 (17%)
Query: 19 PPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEA 78
P S + + +LRLV + GR+E+ H+G WGT+CDD++ + +A V CRQLG
Sbjct: 706 PEESAVACIESGQLRLVNGGGRCA-GRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGE 764
Query: 79 ALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHR 138
A+ SA +G+G GPIWLD ++C G ES + QC S+GWG +C H ED GVIC
Sbjct: 765 AINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVIC------ 818
Query: 139 GYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMN 198
SE +S L + R G +EV Y G W V +
Sbjct: 819 ---SEFMSLRLTSEASR-----------------EACAGRLEVFYNGAWGTVGKSSMSET 858
Query: 199 NSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHM 258
VVC LG + ++ K + M W+ V
Sbjct: 859 TVGVVCRQLGCADKGKINPASLDKAMSIPM----------------WVDNV--------- 893
Query: 259 ANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRSGAQ 318
CP G + C + P + P + + ++RL+ G
Sbjct: 894 ----------------QCPKGPDTLWQCPSSP-WEKRLASPSEETWITCDNKIRLQEGPT 936
Query: 319 VGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEV 378
GRVE+ WGTVCD W+L A VVC+QLG G A +A A GQG GPI L+EV
Sbjct: 937 SCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEV 996
Query: 379 RCRGYERTLSDCPALEGSQNGCQHENDAAVRC 410
+C+G E +L DCPA + C H+ DAAV C
Sbjct: 997 KCKGNESSLWDCPARRWGHSECGHKEDAAVNC 1028
Score = 205 bits (521), Expect = 1e-52
Identities = 152/497 (30%), Positives = 221/497 (44%), Gaps = 80/497 (16%)
Query: 26 SLGTT--KLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWA 83
SLG T +LRLV E+K GR+EV Q +WGTVC++ ++++ +V C QLG A+
Sbjct: 43 SLGGTDKELRLVDGENKCS-GRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAP 101
Query: 84 HSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGV-SDCSHSEDVGVICHPRRHRGYLS 142
A G G IW+D+V C G ES+L C +GWG S+C+H +D GV C
Sbjct: 102 GWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTC---------- 151
Query: 143 ETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRV 202
G L E+RL + + G +E+K++G W VCD + ++++ V
Sbjct: 152 --------SDGSNL-EMRL-------TRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASV 195
Query: 203 VCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQ 262
+C L S V S W + C G E + NC+
Sbjct: 196 ICRQLECGSAVSFSG--------------SSNFGE--GSGPIWFDDLICNGNESALWNCK 239
Query: 263 VQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRSGAQVGEG 322
Q G + C A V C G + +RL G G
Sbjct: 240 HQ-----GWGKHNCDHAEDAGVICSKG-----------------ADLSLRLVDGVTECSG 277
Query: 323 RVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRG 382
R+EV +WGT+CD W+ A+V C+QLG +A A+ +G G I L V C+G
Sbjct: 278 RLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQG 337
Query: 383 YERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEGLLEVQVEVNG 442
+E + C E ++ C H DA V C + G ++RL GG G +EV+++
Sbjct: 338 HEPAVWQCKHHEWGKHYCNHNEDAGVTC---SDGSDLELRLRGGGSRCAGTVEVEIQ--- 391
Query: 443 VPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTEL 502
G VC WGL EA V CRQLG G A+ K ++ +A + C+G E
Sbjct: 392 -RLLGKVCDRGWGLKEADVVCRQLGCGSAL---KTSYQVYSKIQATNTWLFLSSCNGNET 447
Query: 503 ALQQCQ--RHGPVHCSH 517
+L C+ + G + C H
Sbjct: 448 SLWDCKNWQWGGLTCDH 464
Score = 202 bits (513), Expect = 1e-51
Identities = 139/444 (31%), Positives = 195/444 (43%), Gaps = 63/444 (14%)
Query: 33 RLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGE 92
RLVG + P GR+EV H WG++CD +F+++ A+V CR+L ++ A +G+G
Sbjct: 479 RLVGGDI-PCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGN 537
Query: 93 GPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGPQ 152
G IW + +C G ES L C CSHS DVGV+C
Sbjct: 538 GQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCS------------------- 578
Query: 153 GRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGML--GFP 210
R E+RL +P EG VE+K G W +C+ W + ++ V+C L G
Sbjct: 579 --RYTEIRL------VNGKTPC-EGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVA 629
Query: 211 SEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQV-----QV 265
P + + + W H C GTE HM +C V +
Sbjct: 630 LSTPGGARFGK------------------GNGQIWRHMFHCTGTEQHMGDCPVTALGASL 671
Query: 266 APARGKLRPACPGGMHAVVSCVAGPHFRPPK-TKPQRKG-SWAEEPRVRLRSGAQVGEGR 323
P+ C G +S P + T P+ + E ++RL +G GR
Sbjct: 672 CPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGR 731
Query: 324 VEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGY 383
VE+ WGT+CD W+L A VVCRQLG G A A A G+G GPI L E++C G
Sbjct: 732 VEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGK 791
Query: 384 ERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEGLLEVQVEVNGV 443
E + C + Q C+H+ DA V C+ F + +RL E ++V NG
Sbjct: 792 ESRIWQCHSHGWGQQNCRHKEDAGVICS----EFMS-LRLTSEASREACAGRLEVFYNGA 846
Query: 444 PRWGSVCSENWGLTEAMVACRQLG 467
WG+V + T V CRQLG
Sbjct: 847 --WGTVGKSSMSETTVGVVCRQLG 868
Score = 179 bits (455), Expect = 6e-45
Identities = 143/512 (27%), Positives = 223/512 (43%), Gaps = 73/512 (14%)
Query: 30 TKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYG 89
T++RLV ++ P EGR+E+ G WG++C+ ++ I++A V C+QL AL+ A++G
Sbjct: 581 TEIRLVNGKT-PCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFG 639
Query: 90 QGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNAL 149
+G G IW C GTE + C G S C + VIC + + LS S++L
Sbjct: 640 KGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQT-LSSCNSSSL 698
Query: 150 GPQGRRLEEVRLKPILASAKQH----SPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCG 205
GP + E + S + G VE+ +EG W +CD W ++++ VVC
Sbjct: 699 GPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCR 758
Query: 206 MLGFPSEVPV--DSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQV 263
LG + +H+ W+ ++ C G E + C
Sbjct: 759 QLGCGEAINATGSAHFGE------------------GTGPIWLDEMKCNGKESRIWQCH- 799
Query: 264 QVAPARGKLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRSGA--QVGE 321
+ G + C A V C +E +RL S A +
Sbjct: 800 ----SHGWGQQNCRHKEDAGVIC-------------------SEFMSLRLTSEASREACA 836
Query: 322 GRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLG-PIHLSEVRC 380
GR+EV N WGTV + + VVCRQLG + + A L + + P+ + V+C
Sbjct: 837 GRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCAD-KGKINPASLDKAMSIPMWVDNVQC 895
Query: 381 RGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEGLLEVQVEV 440
TL CP+ + + + C+ N++RL G G +VE+
Sbjct: 896 PKGPDTLWQCPSSPWEKRLASPSEETWITCD-------NKIRLQEGPTSCSG----RVEI 944
Query: 441 NGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGT 500
WG+VC ++W L +A V C+QLG G A+ A+KE F GT + ++ V+C G
Sbjct: 945 WHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGT---GPIWLNEVKCKGN 1001
Query: 501 ELALQQC--QRHGPVHCSHGGGRFLAGVSCMD 530
E +L C +R G C H + A V+C D
Sbjct: 1002 ESSLWDCPARRWGHSECGH---KEDAAVNCTD 1030
Score = 164 bits (415), Expect = 3e-40
Identities = 141/526 (26%), Positives = 206/526 (39%), Gaps = 103/526 (19%)
Query: 31 KLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQ 90
+LRL G S+ G +EV Q G VCD + ++EA V CRQLG +AL ++
Sbjct: 372 ELRLRGGGSRCA-GTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKI 430
Query: 91 GEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALG 150
WL C G E+SL C + WG C H E+ + C R + +
Sbjct: 431 QATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREPRLVGGDIP---- 486
Query: 151 PQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFP 210
G VEVK+ W +CD +++ + V+C L
Sbjct: 487 ------------------------CSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCG 522
Query: 211 SEVPV--DSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPA 268
+ V + +H+ W + C G E H++ C V P
Sbjct: 523 TVVSILGGAHFGE------------------GNGQIWAEEFQCEGHESHLSLCPVAPRP- 563
Query: 269 RGKLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLM 328
C V C + +RL +G EGRVE+
Sbjct: 564 ----EGTCSHSRDVGVVC-------------------SRYTEIRLVNGKTPCEGRVELKT 600
Query: 329 NRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGYERTLS 388
WG++C+ W++ A V+C+QL G A GAR G+G G I C G E+ +
Sbjct: 601 LGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMG 660
Query: 389 DCPALEGSQNGCQHENDAAVRCN---VPNMGFQNQVRLAGGR--IPEE------------ 431
DCP + C E A+V C+ + N L R IPEE
Sbjct: 661 DCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESGQLR 720
Query: 432 -----GLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPR 486
G +VE+ WG++C ++W L++A V CRQLG G AI+A F GT
Sbjct: 721 LVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGT-- 778
Query: 487 AQEVVMSGVRCSGTELALQQCQRH--GPVHCSHGGGRFLAGVSCMD 530
+ + ++C+G E + QC H G +C H + AGV C +
Sbjct: 779 -GPIWLDEMKCNGKESRIWQCHSHGWGQQNCRH---KEDAGVICSE 820
Score = 157 bits (397), Expect = 3e-38
Identities = 107/358 (29%), Positives = 155/358 (43%), Gaps = 52/358 (14%)
Query: 177 GAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLK 236
G VEVK + W VC+ GW+M V+C LG P+ + W
Sbjct: 62 GRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPG------W----------AN 105
Query: 237 SLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPK 296
S W+ V+C G E + +C+ GK C A V+C G +
Sbjct: 106 SSAGSGRIWMDHVSCRGNESALWDCKHD---GWGK-HSNCTHQQDAGVTCSDGSNLE--- 158
Query: 297 TKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGS 356
+RL G + GR+E+ +WGTVCD +N+ ASV+CRQL GS
Sbjct: 159 --------------MRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGS 204
Query: 357 AREALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMG 416
A + G+G GPI ++ C G E L +C ++ C H DA V C + G
Sbjct: 205 AVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVIC---SKG 261
Query: 417 FQNQVRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYK 476
+RL G G LEV+ + WG++C + W +A VAC+QLG A+ A
Sbjct: 262 ADLSLRLVDGVTECSGRLEVRFQ----GEWGTICDDGWDSYDAAVACKQLGCPTAVTAIG 317
Query: 477 ETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRH--GPVHCSHGGGRFLAGVSCMDSA 532
+ + + + V C G E A+ QC+ H G +C+H AGV+C D +
Sbjct: 318 RV---NASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNED---AGVTCSDGS 369
Score = 116 bits (291), Expect = 7e-26
Identities = 78/228 (34%), Positives = 111/228 (48%), Gaps = 16/228 (7%)
Query: 308 EPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLG 367
+ +RL G GRVEV + +WGTVC++ W++ + SV+C QLG +A +A A
Sbjct: 48 DKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSS 107
Query: 368 QGLGPIHLSEVRCRGYERTLSDCPALE-GSQNGCQHENDAAVRCNVPNMGFQNQVRLAGG 426
G G I + V CRG E L DC G + C H+ DA V C + G ++RL G
Sbjct: 108 AGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTC---SDGSNLEMRLTRG 164
Query: 427 RIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPR 486
G +E++ + RWG+VC +N+ + A V CRQL G A+ + F G
Sbjct: 165 GNMCSGRIEIKFQ----GRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEG--- 217
Query: 487 AQEVVMSGVRCSGTELALQQC--QRHGPVHCSHGGGRFLAGVSCMDSA 532
+ + + C+G E AL C Q G +C H AGV C A
Sbjct: 218 SGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAED---AGVICSKGA 262
>gi|44662834 CD163 antigen isoform a [Homo sapiens]
Length = 1156
Score = 213 bits (542), Expect = 5e-55
Identities = 147/466 (31%), Positives = 200/466 (42%), Gaps = 80/466 (17%)
Query: 44 GRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCV 103
GR+E+ QG+WGTVCDDNF I A+V CRQL +A++++ S+ +G+G GPIW D++ C
Sbjct: 170 GRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEGSGPIWFDDLICN 229
Query: 104 GTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKP 163
G ES+L C GWG +C H+ED GVIC K
Sbjct: 230 GNESALWNCKHQGWGKHNCDHAEDAGVICS----------------------------KG 261
Query: 164 ILASAKQHSPVTE--GAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYR 221
S + VTE G +EV+++G W +CD GW ++ V C LG P+ V
Sbjct: 262 ADLSLRLVDGVTECSGRLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIG---- 317
Query: 222 KVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMH 281
R+ + W+ V+C G EP + C+ GK C
Sbjct: 318 ------------RVNASKGFGHIWLDSVSCQGHEPAVWQCKHH---EWGK--HYCNHNED 360
Query: 282 AVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWN 341
A V+C G + +RLR G G VEV + R G VCD W
Sbjct: 361 AGVTCSDG-----------------SDLELRLRGGGSRCAGTVEVEIQRLLGKVCDRGWG 403
Query: 342 LISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQ 401
L A VVCRQLG GSA + + L C G E +L DC + C
Sbjct: 404 LKEADVVCRQLGCGSALKTSYQVYSKIQATNTWLFLSSCNGNETSLWDCKNWQWGGLTCD 463
Query: 402 HENDAAVRCNVPNMGFQNQVRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMV 461
H +A + C+ + RL GG IP G +VEV WGS+C ++ L A V
Sbjct: 464 HYEEAKITCSA-----HREPRLVGGDIPCSG----RVEVKHGDTWGSICDSDFSLEAASV 514
Query: 462 ACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQC 507
CR+L G + F G ++ +C G E L C
Sbjct: 515 LCRELQCGTVVSILGGAHFGEGN---GQIWAEEFQCEGHESHLSLC 557
Score = 207 bits (527), Expect = 3e-53
Identities = 130/392 (33%), Positives = 177/392 (45%), Gaps = 69/392 (17%)
Query: 19 PPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEA 78
P S + + +LRLV + GR+E+ H+G WGT+CDD++ + +A V CRQLG
Sbjct: 706 PEESAVACIESGQLRLVNGGGRCA-GRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGE 764
Query: 79 ALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHR 138
A+ SA +G+G GPIWLD ++C G ES + QC S+GWG +C H ED GVIC
Sbjct: 765 AINATGSAHFGEGTGPIWLDEMKCNGKESRIWQCHSHGWGQQNCRHKEDAGVIC------ 818
Query: 139 GYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMN 198
SE +S L + R G +EV Y G W V +
Sbjct: 819 ---SEFMSLRLTSEASR-----------------EACAGRLEVFYNGAWGTVGKSSMSET 858
Query: 199 NSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHM 258
VVC LG + ++ K + M W+ V
Sbjct: 859 TVGVVCRQLGCADKGKINPASLDKAMSIPM----------------WVDNV--------- 893
Query: 259 ANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRSGAQ 318
CP G + C + P + P + + ++RL+ G
Sbjct: 894 ----------------QCPKGPDTLWQCPSSP-WEKRLASPSEETWITCDNKIRLQEGPT 936
Query: 319 VGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEV 378
GRVE+ WGTVCD W+L A VVC+QLG G A +A A GQG GPI L+EV
Sbjct: 937 SCSGRVEIWHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGTGPIWLNEV 996
Query: 379 RCRGYERTLSDCPALEGSQNGCQHENDAAVRC 410
+C+G E +L DCPA + C H+ DAAV C
Sbjct: 997 KCKGNESSLWDCPARRWGHSECGHKEDAAVNC 1028
Score = 205 bits (521), Expect = 1e-52
Identities = 152/497 (30%), Positives = 221/497 (44%), Gaps = 80/497 (16%)
Query: 26 SLGTT--KLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWA 83
SLG T +LRLV E+K GR+EV Q +WGTVC++ ++++ +V C QLG A+
Sbjct: 43 SLGGTDKELRLVDGENKCS-GRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAP 101
Query: 84 HSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGV-SDCSHSEDVGVICHPRRHRGYLS 142
A G G IW+D+V C G ES+L C +GWG S+C+H +D GV C
Sbjct: 102 GWANSSAGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTC---------- 151
Query: 143 ETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRV 202
G L E+RL + + G +E+K++G W VCD + ++++ V
Sbjct: 152 --------SDGSNL-EMRL-------TRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASV 195
Query: 203 VCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQ 262
+C L S V S W + C G E + NC+
Sbjct: 196 ICRQLECGSAVSFSG--------------SSNFGE--GSGPIWFDDLICNGNESALWNCK 239
Query: 263 VQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRSGAQVGEG 322
Q G + C A V C G + +RL G G
Sbjct: 240 HQ-----GWGKHNCDHAEDAGVICSKG-----------------ADLSLRLVDGVTECSG 277
Query: 323 RVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRG 382
R+EV +WGT+CD W+ A+V C+QLG +A A+ +G G I L V C+G
Sbjct: 278 RLEVRFQGEWGTICDDGWDSYDAAVACKQLGCPTAVTAIGRVNASKGFGHIWLDSVSCQG 337
Query: 383 YERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEGLLEVQVEVNG 442
+E + C E ++ C H DA V C + G ++RL GG G +EV+++
Sbjct: 338 HEPAVWQCKHHEWGKHYCNHNEDAGVTC---SDGSDLELRLRGGGSRCAGTVEVEIQ--- 391
Query: 443 VPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTEL 502
G VC WGL EA V CRQLG G A+ K ++ +A + C+G E
Sbjct: 392 -RLLGKVCDRGWGLKEADVVCRQLGCGSAL---KTSYQVYSKIQATNTWLFLSSCNGNET 447
Query: 503 ALQQCQ--RHGPVHCSH 517
+L C+ + G + C H
Sbjct: 448 SLWDCKNWQWGGLTCDH 464
Score = 202 bits (513), Expect = 1e-51
Identities = 139/444 (31%), Positives = 195/444 (43%), Gaps = 63/444 (14%)
Query: 33 RLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGE 92
RLVG + P GR+EV H WG++CD +F+++ A+V CR+L ++ A +G+G
Sbjct: 479 RLVGGDI-PCSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCGTVVSILGGAHFGEGN 537
Query: 93 GPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGPQ 152
G IW + +C G ES L C CSHS DVGV+C
Sbjct: 538 GQIWAEEFQCEGHESHLSLCPVAPRPEGTCSHSRDVGVVCS------------------- 578
Query: 153 GRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGML--GFP 210
R E+RL +P EG VE+K G W +C+ W + ++ V+C L G
Sbjct: 579 --RYTEIRL------VNGKTPC-EGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVA 629
Query: 211 SEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQV-----QV 265
P + + + W H C GTE HM +C V +
Sbjct: 630 LSTPGGARFGK------------------GNGQIWRHMFHCTGTEQHMGDCPVTALGASL 671
Query: 266 APARGKLRPACPGGMHAVVSCVAGPHFRPPK-TKPQRKG-SWAEEPRVRLRSGAQVGEGR 323
P+ C G +S P + T P+ + E ++RL +G GR
Sbjct: 672 CPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESGQLRLVNGGGRCAGR 731
Query: 324 VEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGY 383
VE+ WGT+CD W+L A VVCRQLG G A A A G+G GPI L E++C G
Sbjct: 732 VEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGTGPIWLDEMKCNGK 791
Query: 384 ERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEGLLEVQVEVNGV 443
E + C + Q C+H+ DA V C+ F + +RL E ++V NG
Sbjct: 792 ESRIWQCHSHGWGQQNCRHKEDAGVICS----EFMS-LRLTSEASREACAGRLEVFYNGA 846
Query: 444 PRWGSVCSENWGLTEAMVACRQLG 467
WG+V + T V CRQLG
Sbjct: 847 --WGTVGKSSMSETTVGVVCRQLG 868
Score = 179 bits (455), Expect = 6e-45
Identities = 143/512 (27%), Positives = 223/512 (43%), Gaps = 73/512 (14%)
Query: 30 TKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYG 89
T++RLV ++ P EGR+E+ G WG++C+ ++ I++A V C+QL AL+ A++G
Sbjct: 581 TEIRLVNGKT-PCEGRVELKTLGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFG 639
Query: 90 QGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNAL 149
+G G IW C GTE + C G S C + VIC + + LS S++L
Sbjct: 640 KGNGQIWRHMFHCTGTEQHMGDCPVTALGASLCPSEQVASVICSGNQSQT-LSSCNSSSL 698
Query: 150 GPQGRRLEEVRLKPILASAKQH----SPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCG 205
GP + E + S + G VE+ +EG W +CD W ++++ VVC
Sbjct: 699 GPTRPTIPEESAVACIESGQLRLVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCR 758
Query: 206 MLGFPSEVPV--DSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQV 263
LG + +H+ W+ ++ C G E + C
Sbjct: 759 QLGCGEAINATGSAHFGE------------------GTGPIWLDEMKCNGKESRIWQCH- 799
Query: 264 QVAPARGKLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRSGA--QVGE 321
+ G + C A V C +E +RL S A +
Sbjct: 800 ----SHGWGQQNCRHKEDAGVIC-------------------SEFMSLRLTSEASREACA 836
Query: 322 GRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLG-PIHLSEVRC 380
GR+EV N WGTV + + VVCRQLG + + A L + + P+ + V+C
Sbjct: 837 GRLEVFYNGAWGTVGKSSMSETTVGVVCRQLGCAD-KGKINPASLDKAMSIPMWVDNVQC 895
Query: 381 RGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGRIPEEGLLEVQVEV 440
TL CP+ + + + C+ N++RL G G +VE+
Sbjct: 896 PKGPDTLWQCPSSPWEKRLASPSEETWITCD-------NKIRLQEGPTSCSG----RVEI 944
Query: 441 NGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGT 500
WG+VC ++W L +A V C+QLG G A+ A+KE F GT + ++ V+C G
Sbjct: 945 WHGGSWGTVCDDSWDLDDAQVVCQQLGCGPALKAFKEAEFGQGT---GPIWLNEVKCKGN 1001
Query: 501 ELALQQC--QRHGPVHCSHGGGRFLAGVSCMD 530
E +L C +R G C H + A V+C D
Sbjct: 1002 ESSLWDCPARRWGHSECGH---KEDAAVNCTD 1030
Score = 164 bits (415), Expect = 3e-40
Identities = 141/526 (26%), Positives = 206/526 (39%), Gaps = 103/526 (19%)
Query: 31 KLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQ 90
+LRL G S+ G +EV Q G VCD + ++EA V CRQLG +AL ++
Sbjct: 372 ELRLRGGGSRCA-GTVEVEIQRLLGKVCDRGWGLKEADVVCRQLGCGSALKTSYQVYSKI 430
Query: 91 GEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALG 150
WL C G E+SL C + WG C H E+ + C R + +
Sbjct: 431 QATNTWLFLSSCNGNETSLWDCKNWQWGGLTCDHYEEAKITCSAHREPRLVGGDIP---- 486
Query: 151 PQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFP 210
G VEVK+ W +CD +++ + V+C L
Sbjct: 487 ------------------------CSGRVEVKHGDTWGSICDSDFSLEAASVLCRELQCG 522
Query: 211 SEVPV--DSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPA 268
+ V + +H+ W + C G E H++ C V P
Sbjct: 523 TVVSILGGAHFGE------------------GNGQIWAEEFQCEGHESHLSLCPVAPRP- 563
Query: 269 RGKLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLM 328
C V C + +RL +G EGRVE+
Sbjct: 564 ----EGTCSHSRDVGVVC-------------------SRYTEIRLVNGKTPCEGRVELKT 600
Query: 329 NRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGYERTLS 388
WG++C+ W++ A V+C+QL G A GAR G+G G I C G E+ +
Sbjct: 601 LGAWGSLCNSHWDIEDAHVLCQQLKCGVALSTPGGARFGKGNGQIWRHMFHCTGTEQHMG 660
Query: 389 DCPALEGSQNGCQHENDAAVRCN---VPNMGFQNQVRLAGGR--IPEE------------ 431
DCP + C E A+V C+ + N L R IPEE
Sbjct: 661 DCPVTALGASLCPSEQVASVICSGNQSQTLSSCNSSSLGPTRPTIPEESAVACIESGQLR 720
Query: 432 -----GLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPR 486
G +VE+ WG++C ++W L++A V CRQLG G AI+A F GT
Sbjct: 721 LVNGGGRCAGRVEIYHEGSWGTICDDSWDLSDAHVVCRQLGCGEAINATGSAHFGEGT-- 778
Query: 487 AQEVVMSGVRCSGTELALQQCQRH--GPVHCSHGGGRFLAGVSCMD 530
+ + ++C+G E + QC H G +C H + AGV C +
Sbjct: 779 -GPIWLDEMKCNGKESRIWQCHSHGWGQQNCRH---KEDAGVICSE 820
Score = 157 bits (397), Expect = 3e-38
Identities = 107/358 (29%), Positives = 155/358 (43%), Gaps = 52/358 (14%)
Query: 177 GAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLK 236
G VEVK + W VC+ GW+M V+C LG P+ + W
Sbjct: 62 GRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPG------W----------AN 105
Query: 237 SLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPK 296
S W+ V+C G E + +C+ GK C A V+C G +
Sbjct: 106 SSAGSGRIWMDHVSCRGNESALWDCKHD---GWGK-HSNCTHQQDAGVTCSDGSNLE--- 158
Query: 297 TKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGS 356
+RL G + GR+E+ +WGTVCD +N+ ASV+CRQL GS
Sbjct: 159 --------------MRLTRGGNMCSGRIEIKFQGRWGTVCDDNFNIDHASVICRQLECGS 204
Query: 357 AREALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMG 416
A + G+G GPI ++ C G E L +C ++ C H DA V C + G
Sbjct: 205 AVSFSGSSNFGEGSGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAEDAGVIC---SKG 261
Query: 417 FQNQVRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYK 476
+RL G G LEV+ + WG++C + W +A VAC+QLG A+ A
Sbjct: 262 ADLSLRLVDGVTECSGRLEVRFQ----GEWGTICDDGWDSYDAAVACKQLGCPTAVTAIG 317
Query: 477 ETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRH--GPVHCSHGGGRFLAGVSCMDSA 532
+ + + + V C G E A+ QC+ H G +C+H AGV+C D +
Sbjct: 318 RV---NASKGFGHIWLDSVSCQGHEPAVWQCKHHEWGKHYCNHNED---AGVTCSDGS 369
Score = 116 bits (291), Expect = 7e-26
Identities = 78/228 (34%), Positives = 111/228 (48%), Gaps = 16/228 (7%)
Query: 308 EPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLG 367
+ +RL G GRVEV + +WGTVC++ W++ + SV+C QLG +A +A A
Sbjct: 48 DKELRLVDGENKCSGRVEVKVQEEWGTVCNNGWSMEAVSVICNQLGCPTAIKAPGWANSS 107
Query: 368 QGLGPIHLSEVRCRGYERTLSDCPALE-GSQNGCQHENDAAVRCNVPNMGFQNQVRLAGG 426
G G I + V CRG E L DC G + C H+ DA V C + G ++RL G
Sbjct: 108 AGSGRIWMDHVSCRGNESALWDCKHDGWGKHSNCTHQQDAGVTC---SDGSNLEMRLTRG 164
Query: 427 RIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPR 486
G +E++ + RWG+VC +N+ + A V CRQL G A+ + F G
Sbjct: 165 GNMCSGRIEIKFQ----GRWGTVCDDNFNIDHASVICRQLECGSAVSFSGSSNFGEG--- 217
Query: 487 AQEVVMSGVRCSGTELALQQC--QRHGPVHCSHGGGRFLAGVSCMDSA 532
+ + + C+G E AL C Q G +C H AGV C A
Sbjct: 218 SGPIWFDDLICNGNESALWNCKHQGWGKHNCDHAED---AGVICSKGA 262
>gi|5174411 CD5 molecule-like [Homo sapiens]
Length = 347
Score = 164 bits (415), Expect = 3e-40
Identities = 127/399 (31%), Positives = 175/399 (43%), Gaps = 74/399 (18%)
Query: 22 SRPQSLGTTK-LRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAAL 80
+RP L + +RLVG + E GR+EV +GQWGTVCDD + I++ V CR+LG AA
Sbjct: 13 TRPGFLASPSGVRLVGGLHRCE-GRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAAS 71
Query: 81 TWAHSAKY---GQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRH 137
Y + E + + +V C GTE +L QC V DCSH ED G C
Sbjct: 72 GTPSGILYEPPAEKEQKVLIQSVSCTGTEDTLAQCEQE--EVYDCSHDEDAGASCE---- 125
Query: 138 RGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTM 197
+ S + P+G R LA H +G VEVK++ W VC GW++
Sbjct: 126 ----NPESSFSPVPEGVR---------LADGPGH---CKGRVEVKHQNQWYTVCQTGWSL 169
Query: 198 NNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPH 257
++VVC LG V K K + W+ Q++C G E
Sbjct: 170 RAAKVVCRQLGCGRAVLTQ---------------KRCNKHAYGRKPIWLSQMSCSGREAT 214
Query: 258 MANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKGSW--AEEP-RVRLR 314
+ +C P+ P G + T + +W E+P +RL
Sbjct: 215 LQDC------------PSGPWGKN---------------TCNHDEDTWVECEDPFDLRLV 247
Query: 315 SGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGAR--LGQGLGP 372
G + GR+EVL WG+VCD W VVC+QLG G + F R G G+G
Sbjct: 248 GGDNLCSGRLEVLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKSLSPSFRDRKCYGPGVGR 307
Query: 373 IHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCN 411
I L VRC G E++L C + C H+ D AV C+
Sbjct: 308 IWLDNVRCSGEEQSLEQCQHRFWGFHDCTHQEDVAVICS 346
Score = 156 bits (394), Expect = 8e-38
Identities = 116/349 (33%), Positives = 160/349 (45%), Gaps = 52/349 (14%)
Query: 176 EGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRL 235
EG VEV+ +G W VCD GW + + V+C LG + S + +P +
Sbjct: 34 EGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGTPSGI--------LYEPPAE- 84
Query: 236 KSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPP 295
+ I V+C GTE +A C+ + C A SC
Sbjct: 85 ----KEQKVLIQSVSCTGTEDTLAQCEQEEVYD-------CSHDEDAGASC--------- 124
Query: 296 KTKPQRKGSWAEEPR-VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGF 354
+ S++ P VRL G +GRVEV QW TVC W+L +A VVCRQLG
Sbjct: 125 ---ENPESSFSPVPEGVRLADGPGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGC 181
Query: 355 GSAREALFGARLGQ---GLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCN 411
G R L R + G PI LS++ C G E TL DCP+ +N C H+ D V C
Sbjct: 182 G--RAVLTQKRCNKHAYGRKPIWLSQMSCSGREATLQDCPSGPWGKNTCNHDEDTWVECE 239
Query: 412 VPNMGFQNQVRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFA 471
P +RL GG + L ++EV WGSVC +NWG E V C+QLG G +
Sbjct: 240 DP-----FDLRLVGG----DNLCSGRLEVLHKGVWGSVCDDNWGEKEDQVVCKQLGCGKS 290
Query: 472 IH-AYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRH--GPVHCSH 517
+ ++++ + P + + VRCSG E +L+QCQ G C+H
Sbjct: 291 LSPSFRDRKCYG--PGVGRIWLDNVRCSGEEQSLEQCQHRFWGFHDCTH 337
Score = 112 bits (281), Expect = 1e-24
Identities = 82/233 (35%), Positives = 101/233 (43%), Gaps = 32/233 (13%)
Query: 301 RKGSWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREA 360
R G A VRL G EGRVEV QWGTVCD W++ +V+CR+LG G+A
Sbjct: 14 RPGFLASPSGVRLVGGLHRCEGRVEVEQKGQWGTVCDDGWDIKDVAVLCRELGCGAASGT 73
Query: 361 LFGARL---GQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGF 417
G + + + V C G E TL+ C E C H+ DA C P F
Sbjct: 74 PSGILYEPPAEKEQKVLIQSVSCTGTEDTLAQCEQEE--VYDCSHDEDAGASCENPESSF 131
Query: 418 Q---NQVRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAI-- 472
VRLA G G + +VEV +W +VC W L A V CRQLG G A+
Sbjct: 132 SPVPEGVRLADG----PGHCKGRVEVKHQNQWYTVCQTGWSLRAAKVVCRQLGCGRAVLT 187
Query: 473 ------HAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQR--HGPVHCSH 517
HAY W +S + CSG E LQ C G C+H
Sbjct: 188 QKRCNKHAYGRKPIW----------LSQMSCSGREATLQDCPSGPWGKNTCNH 230
>gi|239752563 PREDICTED: hypothetical protein [Homo sapiens]
Length = 343
Score = 142 bits (359), Expect = 9e-34
Identities = 95/270 (35%), Positives = 132/270 (48%), Gaps = 47/270 (17%)
Query: 43 EGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRC 102
+GR+EVL++G WGTVCDD++ +A V CRQLG A+ +A++GQG GPI LD+VRC
Sbjct: 28 QGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDDVRC 87
Query: 103 VGTESSLDQCGSNGWGVSDCSHSEDVGVICH------PRRHRGYLSETVSNALGPQGRRL 156
G ES L C NGW +C HSED GVIC P R R + S + + +GP+
Sbjct: 88 SGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRSWPSRFLCSPIGPE---- 143
Query: 157 EEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGML--GFPSEVP 214
+ L+ + + +G VEV Y G W VCD W N++ VVC L G+ + P
Sbjct: 144 SSLALRLVNGGDR-----CQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATSAP 198
Query: 215 VDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRP 274
++ + + + + D V C G E ++ +C P G L
Sbjct: 199 GNARFGQGSGPIVLDD------------------VRCSGHESYLWSC-----PNNGWLSH 235
Query: 275 ACPGGMHAVVSC-----VAGPHFRPPKTKP 299
C A V C VAGP R P+ P
Sbjct: 236 NCGHHEDAGVICSGSWAVAGP--RRPQEMP 263
Score = 133 bits (335), Expect = 5e-31
Identities = 93/240 (38%), Positives = 115/240 (47%), Gaps = 26/240 (10%)
Query: 311 VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGL 370
+RL +G +GRVEVL WGTVCD W+ A+VVCRQLG G A A AR GQG
Sbjct: 18 LRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGS 77
Query: 371 GPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCN-----VPNMGFQNQVRLAG 425
GPI L +VRC G E L CP + C H DA V C+ P R
Sbjct: 78 GPIVLDDVRCSGNESYLWSCPHNGWLSHNCGHSEDAGVICSGGPPRTPIRPRSWPSRFLC 137
Query: 426 GRIPEEGLLEVQVEVNGVPR------------WGSVCSENWGLTEAMVACRQLGLGFAIH 473
I E L +++ VNG R WG+VC ++W +A V CRQLG G+A
Sbjct: 138 SPIGPESSLALRL-VNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWATS 196
Query: 474 AYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRHGPV--HCSHGGGRFLAGVSCMDS 531
A F G + +V+ VRCSG E L C +G + +C H AGV C S
Sbjct: 197 APGNARFGQG---SGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHED---AGVICSGS 250
Score = 132 bits (332), Expect = 1e-30
Identities = 96/272 (35%), Positives = 122/272 (44%), Gaps = 40/272 (14%)
Query: 176 EGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLG--FPSEVPVDSHYYRKVWDLKMRDPKS 233
+G VEV Y G W VCD W N++ VVC LG + P ++ + + + + D
Sbjct: 28 QGRVEVLYRGSWGTVCDDSWDTNDANVVCRQLGCGWAMLAPGNARFGQGSGPIVLDD--- 84
Query: 234 RLKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFR 293
V C G E ++ +C P G L C A V C GP
Sbjct: 85 ---------------VRCSGNESYLWSC-----PHNGWLSHNCGHSEDAGVICSGGPPRT 124
Query: 294 P--PKTKPQRKGSWAEEPR----VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASV 347
P P++ P R P +RL +G +GRVEVL WGTVCD W+ A+V
Sbjct: 125 PIRPRSWPSRFLCSPIGPESSLALRLVNGGDRCQGRVEVLYRGSWGTVCDDSWDTNDANV 184
Query: 348 VCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAA 407
VCRQLG G A A AR GQG GPI L +VRC G+E L CP + C H DA
Sbjct: 185 VCRQLGCGWATSAPGNARFGQGSGPIVLDDVRCSGHESYLWSCPNNGWLSHNCGHHEDAG 244
Query: 408 VRCNVPNMGFQNQVRLAGGRIPEE--GLLEVQ 437
V C+ +AG R P+E GL Q
Sbjct: 245 VICS-------GSWAVAGPRRPQEMPGLARAQ 269
>gi|194018748 CD6 molecule [Homo sapiens]
Length = 668
Score = 134 bits (337), Expect = 3e-31
Identities = 108/331 (32%), Positives = 134/331 (40%), Gaps = 46/331 (13%)
Query: 177 GAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLK 236
G VEV+ E W C W + VC LG S +L
Sbjct: 56 GTVEVRLEASWEPACGALWDSRAAEAVCRALGCGG-AEAASQLAPPTPELPPPPAAGNTS 114
Query: 237 SLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRPPK 296
N + C G E + C+V R G A V+C
Sbjct: 115 VAANATLAGAPALLCSGAEWRL--CEVVEHACRSD-------GRRARVTC---------- 155
Query: 297 TKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGS 356
AE +RL G GRVE+L + +WG+VCD W+L A VVCRQLG G
Sbjct: 156 ---------AENRALRLVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGW 206
Query: 357 AREALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMG 416
A +AL G G GPIH +V C G E L DCP L G Q+ C H+ DA C+
Sbjct: 207 AVQALPGLHFTPGRGPIHRDQVNCSGAEAYLWDCPGLPG-QHYCGHKEDAGAVCSE---- 261
Query: 417 FQNQVRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYK 476
RL GG EG +V+V GV W +VC W +EA V C+ LG G A+ K
Sbjct: 262 -HQSWRLTGGADRCEG--QVEVHFRGV--WNTVCDSEWYPSEAKVLCQSLGCGTAVERPK 316
Query: 477 ETWFWSGTPRAQEVVMSGVRCSGTELALQQC 507
G P + M C+G EL L C
Sbjct: 317 ------GLPHSLSGRMY-YSCNGEELTLSNC 340
Score = 92.0 bits (227), Expect = 2e-18
Identities = 67/218 (30%), Positives = 91/218 (41%), Gaps = 49/218 (22%)
Query: 44 GRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCV 103
GR+E+L G+WG+VCDD + +++A V CRQLG A+ + G GPI D V C
Sbjct: 172 GRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHFTPGRGPIHRDQVNCS 231
Query: 104 GTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKP 163
G E+ L C G C H ED G +C SE S L R
Sbjct: 232 GAEAYLWDCPGLP-GQHYCGHKEDAGAVC---------SEHQSWRLTGGADR-------- 273
Query: 164 ILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKV 223
EG VEV + G W VCD W + ++V+C LG + V
Sbjct: 274 -----------CEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAV---------- 312
Query: 224 WDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANC 261
PK SL+ + + +C G E ++NC
Sbjct: 313 -----ERPKGLPHSLSGRMYY-----SCNGEELTLSNC 340
Score = 81.3 bits (199), Expect = 3e-15
Identities = 68/212 (32%), Positives = 88/212 (41%), Gaps = 10/212 (4%)
Query: 311 VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGL 370
VRL +G+ G VEV + W C W+ +A VCR LG G A A A L
Sbjct: 45 VRLTNGSSSCSGTVEVRLEASWEPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPEL 104
Query: 371 GPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPNMGFQNQVRLAGGR--- 427
P + TL+ PAL S G + V + G + +V A R
Sbjct: 105 PPPPAAGNTSVAANATLAGAPALLCS--GAEWRLCEVVEHACRSDGRRARVTCAENRALR 162
Query: 428 -IPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPR 486
+ G +VE+ WGSVC + W L +A V CRQLG G+A+ A F TP
Sbjct: 163 LVDGGGACAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQALPGLHF---TPG 219
Query: 487 AQEVVMSGVRCSGTELALQQCQ-RHGPVHCSH 517
+ V CSG E L C G +C H
Sbjct: 220 RGPIHRDQVNCSGAEAYLWDCPGLPGQHYCGH 251
Score = 79.0 bits (193), Expect = 2e-14
Identities = 103/418 (24%), Positives = 137/418 (32%), Gaps = 78/418 (18%)
Query: 8 TLFLFLLLLGQPPPSRPQSLGTTK-------------LRLVGPESKPEEGRLEVLHQGQW 54
T L L G P P+ P L T+ +RL S G +EV + W
Sbjct: 8 TGLLTAALSGHPSPAPPDQLNTSSAESELWEPGERLPVRLTNGSSSCS-GTVEVRLEASW 66
Query: 55 GTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGS 114
C + + A CR LG A + A P
Sbjct: 67 EPACGALWDSRAAEAVCRALGCGGAEAASQLAPPTPELPP---------------PPAAG 111
Query: 115 NGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPV 174
N ++ + + ++C R L E V +A GRR +
Sbjct: 112 NTSVAANATLAGAPALLCSGAEWR--LCEVVEHACRSDGRRARVTCAENRALRLVDGGGA 169
Query: 175 TEGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSR 234
G VE+ G W VCD W + ++ VVC LG V
Sbjct: 170 CAGRVEMLEHGEWGSVCDDTWDLEDAHVVCRQLGCGWAVQA----------------LPG 213
Query: 235 LKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSCVAGPHFRP 294
L + QV C G E ++ +C P PG + H
Sbjct: 214 LHFTPGRGPIHRDQVNCSGAEAYLWDC------------PGLPGQHYC-------GHKED 254
Query: 295 PKTKPQRKGSWAEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGF 354
SW RL GA EG+VEV W TVCD W A V+C+ LG
Sbjct: 255 AGAVCSEHQSW------RLTGGADRCEGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGC 308
Query: 355 GSAREALFGARLGQGL-GPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCN 411
G+A E G L L G ++ S C G E TLS+C + N C A V C+
Sbjct: 309 GTAVERPKG--LPHSLSGRMYYS---CNGEELTLSNCSWRFNNSNLCSQSLAARVLCS 361
Score = 42.7 bits (99), Expect = 0.001
Identities = 31/100 (31%), Positives = 43/100 (43%), Gaps = 4/100 (4%)
Query: 43 EGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRC 102
EG++EV +G W TVCD + EA V C+ LG A+ + G ++ C
Sbjct: 275 EGQVEVHFRGVWNTVCDSEWYPSEAKVLCQSLGCGTAVERPKGLPHSL-SGRMYYS---C 330
Query: 103 VGTESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLS 142
G E +L C + CS S V+C R LS
Sbjct: 331 NGEELTLSNCSWRFNNSNLCSQSLAARVLCSASRSLHNLS 370
>gi|20357512 macrophage scavenger receptor 1 isoform type 1 [Homo
sapiens]
Length = 451
Score = 120 bits (302), Expect = 4e-27
Identities = 54/103 (52%), Positives = 68/103 (66%), Gaps = 1/103 (0%)
Query: 30 TKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYG 89
TK+RLVG S P EGR+E+LH GQWGT+CDD + ++ V CR LG+ +A +G
Sbjct: 348 TKVRLVGG-SGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFG 406
Query: 90 QGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVIC 132
QG GPIWL+ V C G ESS+++C WG CSHSED GV C
Sbjct: 407 QGTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTC 449
Score = 95.5 bits (236), Expect = 2e-19
Identities = 49/121 (40%), Positives = 64/121 (52%), Gaps = 3/121 (2%)
Query: 295 PKTKPQRKGSW---AEEPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQ 351
PK + KGS +VRL G+ EGRVE+L + QWGT+CD RW + VVCR
Sbjct: 331 PKGQKGEKGSGNTLTPFTKVRLVGGSGPHEGRVEILHSGQWGTICDDRWEVRVGQVVCRS 390
Query: 352 LGFGSAREALFGARLGQGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCN 411
LG+ + A GQG GPI L+EV C G E ++ +C + C H DA V C
Sbjct: 391 LGYPGVQAVHKAAHFGQGTGPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCT 450
Query: 412 V 412
+
Sbjct: 451 L 451
Score = 56.6 bits (135), Expect = 8e-08
Identities = 36/111 (32%), Positives = 55/111 (49%), Gaps = 12/111 (10%)
Query: 420 QVRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETW 479
+VRL GG P EG +VE+ +WG++C + W + V CR LG +K
Sbjct: 349 KVRLVGGSGPHEG----RVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAH 404
Query: 480 FWSGTPRAQEVVMSGVRCSGTELALQQC--QRHGPVHCSHGGGRFLAGVSC 528
F GT + ++ V C G E ++++C ++ G CSH AGV+C
Sbjct: 405 FGQGT---GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSED---AGVTC 449
Score = 47.8 bits (112), Expect = 4e-05
Identities = 29/113 (25%), Positives = 46/113 (40%), Gaps = 25/113 (22%)
Query: 176 EGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVD--SHYYRKVWDLKMRDPKS 233
EG VE+ + G W +CD W + +VVC LG+P V +H+ +
Sbjct: 360 EGRVEILHSGQWGTICDDRWEVRVGQVVCRSLGYPGVQAVHKAAHFGQ------------ 407
Query: 234 RLKSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSC 286
W+++V C G E + C+++ R AC A V+C
Sbjct: 408 ------GTGPIWLNEVFCFGRESSIEECKIRQWGTR-----ACSHSEDAGVTC 449
>gi|5031863 galectin 3 binding protein [Homo sapiens]
Length = 585
Score = 113 bits (282), Expect = 7e-25
Identities = 62/150 (41%), Positives = 86/150 (57%), Gaps = 10/150 (6%)
Query: 4 SPPATLFLFLLLLGQPPPSRPQSLGTTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFA 63
+PP +++LL+ G Q + +RL + +GR+E+ ++GQWGTVCD+ +
Sbjct: 2 TPPRLFWVWLLVAGT------QGVNDGDMRLADGGAT-NQGRVEIFYRGQWGTVCDNLWD 54
Query: 64 IQEATVACRQLGFEAALTWAHSAKYGQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCS 123
+ +A+V CR LGFE A A +GQG GPI LD V+C GTE+SL C S GW S+C
Sbjct: 55 LTDASVVCRALGFENATQALGRAAFGQGSGPIMLDEVQCTGTEASLADCKSLGWLKSNCR 114
Query: 124 HSEDVGVICHPR---RHRGYLSETVSNALG 150
H D GV+C H LS +S ALG
Sbjct: 115 HERDAGVVCTNETRSTHTLDLSRELSEALG 144
Score = 110 bits (275), Expect = 5e-24
Identities = 52/100 (52%), Positives = 66/100 (66%)
Query: 311 VRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGL 370
+RL G +GRVE+ QWGTVCD+ W+L ASVVCR LGF +A +AL A GQG
Sbjct: 24 MRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGS 83
Query: 371 GPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRC 410
GPI L EV+C G E +L+DC +L ++ C+HE DA V C
Sbjct: 84 GPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVC 123
Score = 55.8 bits (133), Expect = 1e-07
Identities = 38/110 (34%), Positives = 54/110 (49%), Gaps = 12/110 (10%)
Query: 421 VRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWF 480
+RLA G +G +VE+ +WG+VC W LT+A V CR LG A A F
Sbjct: 24 MRLADGGATNQG----RVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAF 79
Query: 481 WSGTPRAQEVVMSGVRCSGTELALQQCQRHG--PVHCSHGGGRFLAGVSC 528
G + +++ V+C+GTE +L C+ G +C H AGV C
Sbjct: 80 GQG---SGPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERD---AGVVC 123
Score = 45.1 bits (105), Expect = 2e-04
Identities = 30/111 (27%), Positives = 43/111 (38%), Gaps = 21/111 (18%)
Query: 176 EGAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRL 235
+G VE+ Y G W VCD W + ++ VVC LGF + R
Sbjct: 34 QGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENAT----------------QALGRA 77
Query: 236 KSLTNKNSFWIHQVTCLGTEPHMANCQVQVAPARGKLRPACPGGMHAVVSC 286
+ +V C GTE +A+C+ + G L+ C A V C
Sbjct: 78 AFGQGSGPIMLDEVQCTGTEASLADCK-----SLGWLKSNCRHERDAGVVC 123
>gi|47271477 scavenger receptor class A, member 5 [Homo sapiens]
Length = 495
Score = 106 bits (264), Expect = 9e-23
Identities = 47/102 (46%), Positives = 66/102 (64%), Gaps = 1/102 (0%)
Query: 32 LRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQG 91
+RLV S P EGR+EV H +WGTVCDD + ++ V CR LGF +A++GQG
Sbjct: 393 IRLVNG-SGPHEGRVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTARFGQG 451
Query: 92 EGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVICH 133
G IW+D+V C GTE ++ +C + WGV++C H+ED V C+
Sbjct: 452 TGRIWMDDVACKGTEETIFRCSFSKWGVTNCGHAEDASVTCN 493
Score = 95.1 bits (235), Expect = 2e-19
Identities = 59/149 (39%), Positives = 72/149 (48%), Gaps = 13/149 (8%)
Query: 270 GKLRPACPGGMHAVVSCVAGPHFRPPKTKPQRKG------SWAEEPR-VRLRSGAQVGEG 322
GKL P GM R PK + KG S E P +RL +G+ EG
Sbjct: 351 GKLGATGPMGMRGFKGD------RGPKGEKGEKGDRAGDASGVEAPMMIRLVNGSGPHEG 404
Query: 323 RVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLGQGLGPIHLSEVRCRG 382
RVEV +R+WGTVCD W+ VVCR LGF E AR GQG G I + +V C+G
Sbjct: 405 RVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTARFGQGTGRIWMDDVACKG 464
Query: 383 YERTLSDCPALEGSQNGCQHENDAAVRCN 411
E T+ C + C H DA+V CN
Sbjct: 465 TEETIFRCSFSKWGVTNCGHAEDASVTCN 493
Score = 59.3 bits (142), Expect = 1e-08
Identities = 38/110 (34%), Positives = 50/110 (45%), Gaps = 12/110 (10%)
Query: 421 VRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWF 480
+RL G P EG +VEV RWG+VC + W + V CR LG Y+ F
Sbjct: 393 IRLVNGSGPHEG----RVEVYHDRRWGTVCDDGWDKKDGDVVCRMLGFRGVEEVYRTARF 448
Query: 481 WSGTPRAQEVVMSGVRCSGTELALQQC--QRHGPVHCSHGGGRFLAGVSC 528
GT R + M V C GTE + +C + G +C H A V+C
Sbjct: 449 GQGTGR---IWMDDVACKGTEETIFRCSFSKWGVTNCGHAED---ASVTC 492
Score = 47.4 bits (111), Expect = 5e-05
Identities = 36/128 (28%), Positives = 50/128 (39%), Gaps = 25/128 (19%)
Query: 134 PRRHRGYLSETVSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQ 193
P+ +G + +A G + P++ S EG VEV ++ W VCD
Sbjct: 370 PKGEKGEKGDRAGDASGVEA---------PMMIRLVNGSGPHEGRVEVYHDRRWGTVCDD 420
Query: 194 GWTMNNSRVVCGMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLG 253
GW + VVC MLGF V YR +R T + W+ V C G
Sbjct: 421 GWDKKDGDVVCRMLGFRGVEEV----YR----------TARFGQGTGR--IWMDDVACKG 464
Query: 254 TEPHMANC 261
TE + C
Sbjct: 465 TEETIFRC 472
>gi|5803080 macrophage receptor with collagenous structure [Homo
sapiens]
Length = 520
Score = 100 bits (250), Expect = 4e-21
Identities = 49/104 (47%), Positives = 61/104 (58%), Gaps = 6/104 (5%)
Query: 29 TTKLRLVGPESKPEEGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKY 88
+ +R+VG ++ GR EV + G WGT+CDD + +A V CR LG+ K
Sbjct: 421 SVSVRIVGSSNR---GRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGRALY---KV 474
Query: 89 GQGEGPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVIC 132
G G G IWLDNV+C GTES+L C N WG DCSH ED GV C
Sbjct: 475 GAGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVEC 518
Score = 80.5 bits (197), Expect = 5e-15
Identities = 43/105 (40%), Positives = 53/105 (50%), Gaps = 3/105 (2%)
Query: 308 EPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLG 367
E V +R GR EV + WGT+CD W A V CR LG+ R AL+ ++G
Sbjct: 419 ENSVSVRIVGSSNRGRAEVYYSGTWGTICDDEWQNSDAIVFCRMLGYSKGR-ALY--KVG 475
Query: 368 QGLGPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNV 412
G G I L V+CRG E TL C + C HE DA V C+V
Sbjct: 476 AGTGQIWLDNVQCRGTESTLWSCTKNSWGHHDCSHEEDAGVECSV 520
Score = 47.0 bits (110), Expect = 7e-05
Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 11/85 (12%)
Query: 446 WGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQ 505
WG++C + W ++A+V CR LG YK +GT ++ + V+C GTE L
Sbjct: 443 WGTICDDEWQNSDAIVFCRMLGYSKGRALYK---VGAGT---GQIWLDNVQCRGTESTLW 496
Query: 506 QCQRHGPVH--CSHGGGRFLAGVSC 528
C ++ H CSH AGV C
Sbjct: 497 SCTKNSWGHHDCSHEED---AGVEC 518
Score = 41.6 bits (96), Expect = 0.003
Identities = 28/117 (23%), Positives = 42/117 (35%), Gaps = 19/117 (16%)
Query: 145 VSNALGPQGRRLEEVRLKPILASAKQHSPVTEGAVEVKYEGHWRQVCDQGWTMNNSRVVC 204
V + G QG + E+ S + G EV Y G W +CD W +++ V C
Sbjct: 401 VKGSSGEQGVKGEKGERGENSVSVRIVGSSNRGRAEVYYSGTWGTICDDEWQNSDAIVFC 460
Query: 205 GMLGFPSEVPVDSHYYRKVWDLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANC 261
MLG+ ++ K W+ V C GTE + +C
Sbjct: 461 RMLGYSK-------------------GRALYKVGAGTGQIWLDNVQCRGTESTLWSC 498
>gi|187936955 HHIP-like protein 1 isoform a [Homo sapiens]
Length = 782
Score = 99.4 bits (246), Expect = 1e-20
Identities = 51/104 (49%), Positives = 65/104 (62%), Gaps = 2/104 (1%)
Query: 31 KLRLVGPESKPE-EGRLEVLHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYG 89
++RLV P GR+EV G+WGTVCDD++ I A V CRQLGF A+ A++G
Sbjct: 672 EVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFG 731
Query: 90 QGEG-PIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVIC 132
QG PI LD+VRC G E +L +C NG G +C H ED GV+C
Sbjct: 732 QGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVC 775
Score = 96.7 bits (239), Expect = 7e-20
Identities = 50/108 (46%), Positives = 64/108 (59%), Gaps = 1/108 (0%)
Query: 308 EPRVRLRSGAQVGEGRVEVLMNRQWGTVCDHRWNLISASVVCRQLGFGSAREALFGARLG 367
E R+ +G G GRVEV + +WGTVCD WN+ A+VVCRQLGF A A+ A G
Sbjct: 672 EVRLVRPAGLSSGSGRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGFAYAVRAVKRAEFG 731
Query: 368 QGLG-PIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNVPN 414
QG PI L +VRC G+ER L +C + C+H+ DA V C+ N
Sbjct: 732 QGGSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDEDAGVVCSHQN 779
Score = 72.4 bits (176), Expect = 1e-12
Identities = 47/130 (36%), Positives = 67/130 (51%), Gaps = 10/130 (7%)
Query: 409 RCNVPNMGFQN-QVRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLG 467
R N + F++ +VRL G V+V V G RWG+VC ++W ++ A V CRQLG
Sbjct: 660 RLNSASRAFRDGEVRLVRPAGLSSGSGRVEVFVGG--RWGTVCDDSWNISGAAVVCRQLG 717
Query: 468 LGFAIHAYKETWFWSGTPRAQEVVMSGVRCSGTELALQQCQRH--GPVHCSHGGGRFLAG 525
+A+ A K F G + +++ VRC+G E L +CQ + G +C H AG
Sbjct: 718 FAYAVRAVKRAEFGQG--GSLPILLDDVRCAGWERNLLECQHNGVGTHNCEHDED---AG 772
Query: 526 VSCMDSAPDL 535
V C PDL
Sbjct: 773 VVCSHQNPDL 782
Score = 38.9 bits (89), Expect = 0.018
Identities = 16/33 (48%), Positives = 19/33 (57%)
Query: 177 GAVEVKYEGHWRQVCDQGWTMNNSRVVCGMLGF 209
G VEV G W VCD W ++ + VVC LGF
Sbjct: 686 GRVEVFVGGRWGTVCDDSWNISGAAVVCRQLGF 718
>gi|20357515 macrophage scavenger receptor 1 isoform type 3 [Homo
sapiens]
Length = 388
Score = 57.4 bits (137), Expect = 5e-08
Identities = 23/40 (57%), Positives = 27/40 (67%)
Query: 93 GPIWLDNVRCVGTESSLDQCGSNGWGVSDCSHSEDVGVIC 132
GPIWL+ V C G ESS+++C WG CSHSED GV C
Sbjct: 347 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTC 386
Score = 38.9 bits (89), Expect = 0.018
Identities = 16/42 (38%), Positives = 22/42 (52%)
Query: 371 GPIHLSEVRCRGYERTLSDCPALEGSQNGCQHENDAAVRCNV 412
GPI L+EV C G E ++ +C + C H DA V C +
Sbjct: 347 GPIWLNEVFCFGRESSIEECKIRQWGTRACSHSEDAGVTCTL 388
>gi|119392081 complement factor I preproprotein [Homo sapiens]
Length = 583
Score = 42.0 bits (97), Expect = 0.002
Identities = 31/101 (30%), Positives = 45/101 (44%), Gaps = 5/101 (4%)
Query: 295 PKTKPQRKGSWAEEPR--VRLRSGAQVGEGRVEVLMNRQWGT--VCDHRWNLISASVVCR 350
P TK G+ E + V L+ G EG VEV + Q T +C W++ A+V C
Sbjct: 96 PGTKFLNNGTCTAEGKFSVSLKHGNTDSEGIVEVKLVDQDKTMFICKSSWSMREANVACL 155
Query: 351 QLGFGSAREALFGARLGQ-GLGPIHLSEVRCRGYERTLSDC 390
LGF + +L + V CRG E +L++C
Sbjct: 156 DLGFQQGADTQRRFKLSDLSINSTECLHVHCRGLETSLAEC 196
Score = 36.2 bits (82), Expect = 0.12
Identities = 26/87 (29%), Positives = 37/87 (42%), Gaps = 4/87 (4%)
Query: 421 VRLAGGRIPEEGLLEVQVEVNGVPRWGSVCSENWGLTEAMVACRQLGLGFAIHAYKETWF 480
V L G EG++EV++ + +C +W + EA VAC L LGF A + F
Sbjct: 114 VSLKHGNTDSEGIVEVKLVDQDKTMF--ICKSSWSMREANVAC--LDLGFQQGADTQRRF 169
Query: 481 WSGTPRAQEVVMSGVRCSGTELALQQC 507
V C G E +L +C
Sbjct: 170 KLSDLSINSTECLHVHCRGLETSLAEC 196
Score = 32.0 bits (71), Expect = 2.2
Identities = 28/97 (28%), Positives = 39/97 (40%), Gaps = 17/97 (17%)
Query: 167 SAKQHSPVTEGAVEVKYEGHWRQ--VCDQGWTMNNSRVVCGMLGFPSEVPVDSHYYRKVW 224
S K + +EG VEVK + +C W+M + V C LGF + D+ K+
Sbjct: 115 SLKHGNTDSEGIVEVKLVDQDKTMFICKSSWSMREANVACLDLGF--QQGADTQRRFKLS 172
Query: 225 DLKMRDPKSRLKSLTNKNSFWIHQVTCLGTEPHMANC 261
DL + NS V C G E +A C
Sbjct: 173 DLSI-------------NSTECLHVHCRGLETSLAEC 196
Score = 31.6 bits (70), Expect = 2.8
Identities = 22/73 (30%), Positives = 35/73 (47%), Gaps = 3/73 (4%)
Query: 43 EGRLEV--LHQGQWGTVCDDNFAIQEATVACRQLGFEAALTWAHSAKYGQ-GEGPIWLDN 99
EG +EV + Q + +C +++++EA VAC LGF+ K +
Sbjct: 124 EGIVEVKLVDQDKTMFICKSSWSMREANVACLDLGFQQGADTQRRFKLSDLSINSTECLH 183
Query: 100 VRCVGTESSLDQC 112
V C G E+SL +C
Sbjct: 184 VHCRGLETSLAEC 196
>gi|148612825 Rap GTPase interactor [Homo sapiens]
Length = 1075
Score = 36.6 bits (83), Expect = 0.089
Identities = 25/72 (34%), Positives = 29/72 (40%), Gaps = 18/72 (25%)
Query: 267 PARGKLRPACPGGMHAVV--------SCVAGP--------HFRPPKTKPQRKGSWAEEP- 309
P G +P CP GMH VV SC P P +T P R WA+ P
Sbjct: 822 PGSGASQPVCPEGMHHVVLDGHLEAPSCPLAPRDPGPAAREVAPERTLPLRGAPWAQAPP 881
Query: 310 -RVRLRSGAQVG 320
R R G+Q G
Sbjct: 882 GRQPSRGGSQAG 893
>gi|166197668 CD5 molecule [Homo sapiens]
Length = 495
Score = 35.0 bits (79), Expect = 0.26
Identities = 31/88 (35%), Positives = 39/88 (44%), Gaps = 23/88 (26%)
Query: 285 SCVAGPH-FRPPKTKPQRKGSWAE------EPRV--RLRSGAQVGEGRVEVLMNRQWGTV 335
SC + H FR K KPQ+ G +P+V RL G+ + EG VEV QW +
Sbjct: 243 SCTSLEHCFR--KIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAAL 300
Query: 336 CDH-------RWNLISASVVCRQLGFGS 356
CD RW VCR+ GS
Sbjct: 301 CDSSSARSSLRW-----EEVCREQQCGS 323
>gi|239753316 PREDICTED: similar to Rho guanine nucleotide exchange
factor 4 [Homo sapiens]
Length = 368
Score = 33.1 bits (74), Expect = 0.98
Identities = 23/91 (25%), Positives = 34/91 (37%), Gaps = 2/91 (2%)
Query: 105 TESSLDQCGSNGWGVSDCSHSEDVGVICHPRRHRGYLSETVSNALGPQGRRLEEVRLKPI 164
T L S+ G+S S S+ GV+C R G + VS + + L
Sbjct: 232 TSGDLGTSSSSSAGLSPGSDSDSSGVVCGGRGGNGGMRGAVSRSWSLES--LRSATAGKD 289
Query: 165 LASAKQHSPVTEGAVEVKYEGHWRQVCDQGW 195
A H+P G + G W+ +GW
Sbjct: 290 AAIPAPHAPSAPGCLASVKPGGWKGAAGRGW 320
>gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo
sapiens]
Length = 432
Score = 33.1 bits (74), Expect = 0.98
Identities = 16/41 (39%), Positives = 22/41 (53%), Gaps = 2/41 (4%)
Query: 42 EEGRLEVLHQ--GQWGTVCDDNFAIQEATVACRQLGFEAAL 80
+ L+VL G W + C DNF A ACRQ+G+ A+
Sbjct: 109 DRSTLQVLDSATGNWFSACFDNFTEALAETACRQMGYSRAV 149
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.136 0.450
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,450,271
Number of Sequences: 37866
Number of extensions: 1629884
Number of successful extensions: 4280
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 31
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 3610
Number of HSP's gapped (non-prelim): 210
length of query: 756
length of database: 18,247,518
effective HSP length: 110
effective length of query: 646
effective length of database: 14,082,258
effective search space: 9097138668
effective search space used: 9097138668
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.