BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|62955044 F-box protein 42 [Homo sapiens] (717 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|62955044 F-box protein 42 [Homo sapiens] 1494 0.0 gi|26190616 kelch domain containing 1 [Homo sapiens] 77 6e-14 gi|98986457 host cell factor 1 [Homo sapiens] 75 3e-13 gi|7657301 kelch domain containing 2 [Homo sapiens] 72 2e-12 gi|7019405 host cell factor C2 [Homo sapiens] 70 7e-12 gi|16945972 kelch domain containing 3 [Homo sapiens] 67 4e-11 gi|21314675 kelch domain containing 4 [Homo sapiens] 65 2e-10 gi|47717139 leucine-zipper-like transcription regulator 1 [Homo ... 63 1e-09 gi|195963410 MEF2 activating motif and SAP domain containing tra... 58 3e-08 gi|145701025 multiple EGF-like-domains 8 [Homo sapiens] 56 1e-07 gi|33695109 Rab9 effector protein with kelch motifs [Homo sapiens] 55 2e-07 gi|44917619 kelch domain containing 10 [Homo sapiens] 54 4e-07 gi|20143482 melanoma antigen family E, 1 [Homo sapiens] 50 6e-06 gi|46410931 attractin-like 1 [Homo sapiens] 50 7e-06 gi|163965366 nascent polypeptide-associated complex alpha subuni... 50 9e-06 gi|21450863 attractin isoform 2 [Homo sapiens] 48 4e-05 gi|21450861 attractin isoform 1 [Homo sapiens] 48 4e-05 gi|146219832 myosin light chain kinase 3 [Homo sapiens] 45 2e-04 gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 44 4e-04 gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 44 5e-04 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 43 9e-04 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 43 9e-04 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 43 0.001 gi|72004269 tetra-peptide repeat homeobox [Homo sapiens] 43 0.001 gi|59806361 hypothetical protein LOC387104 [Homo sapiens] 42 0.003 gi|54860079 nadrin isoform 1 [Homo sapiens] 42 0.003 gi|54860105 nadrin isoform 2 [Homo sapiens] 42 0.003 gi|72256200 B-cell CLL/lymphoma 9 [Homo sapiens] 42 0.003 gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 42 0.003 gi|158508542 kelch-like 33 [Homo sapiens] 41 0.003 >gi|62955044 F-box protein 42 [Homo sapiens] Length = 717 Score = 1494 bits (3868), Expect = 0.0 Identities = 717/717 (100%), Positives = 717/717 (100%) Query: 1 MASSSDSEDDSFMAVDQEETVLEGTMDQDEEPHPVLEAEETRHNRSMSELPEEVLEYILS 60 MASSSDSEDDSFMAVDQEETVLEGTMDQDEEPHPVLEAEETRHNRSMSELPEEVLEYILS Sbjct: 1 MASSSDSEDDSFMAVDQEETVLEGTMDQDEEPHPVLEAEETRHNRSMSELPEEVLEYILS 60 Query: 61 FLSPYQEHKTAALVCKQWYRLIKGVAHQCYHGFMKAVQEGNIQWESRTYPYPGTPITQRF 120 FLSPYQEHKTAALVCKQWYRLIKGVAHQCYHGFMKAVQEGNIQWESRTYPYPGTPITQRF Sbjct: 61 FLSPYQEHKTAALVCKQWYRLIKGVAHQCYHGFMKAVQEGNIQWESRTYPYPGTPITQRF 120 Query: 121 SHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLV 180 SHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLV Sbjct: 121 SHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLV 180 Query: 181 VYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVI 240 VYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVI Sbjct: 181 VYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVI 240 Query: 241 DDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDATILILG 300 DDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDATILILG Sbjct: 241 DDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDATILILG 300 Query: 301 GCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELWCHPACRVGQCVVVFSQAPSG 360 GCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELWCHPACRVGQCVVVFSQAPSG Sbjct: 301 GCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELWCHPACRVGQCVVVFSQAPSG 360 Query: 361 RAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTP 420 RAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTP Sbjct: 361 RAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTP 420 Query: 421 SGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGL 480 SGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGL Sbjct: 421 SGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGL 480 Query: 481 SLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTP 540 SLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTP Sbjct: 481 SLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTP 540 Query: 541 PHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVP 600 PHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVP Sbjct: 541 PHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVP 600 Query: 601 IPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKPLYQSMNCKPMQMYVLDIKDTKEKGRV 660 IPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKPLYQSMNCKPMQMYVLDIKDTKEKGRV Sbjct: 601 IPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKPLYQSMNCKPMQMYVLDIKDTKEKGRV 660 Query: 661 KWKVFNSSSVVGPPETSLHTVVQGRGELIIFGGLMDKKQNVKYYPKTNALYFVRAKR 717 KWKVFNSSSVVGPPETSLHTVVQGRGELIIFGGLMDKKQNVKYYPKTNALYFVRAKR Sbjct: 661 KWKVFNSSSVVGPPETSLHTVVQGRGELIIFGGLMDKKQNVKYYPKTNALYFVRAKR 717 >gi|26190616 kelch domain containing 1 [Homo sapiens] Length = 406 Score = 77.0 bits (188), Expect = 6e-14 Identities = 68/252 (26%), Positives = 117/252 (46%), Gaps = 33/252 (13%) Query: 115 PITQRFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKE----WIRPLA-SGS 169 P + S AC N +Y+FGG + N L+ ++L +++ W + G Sbjct: 66 PASMSGSCGACI---NGKLYIFGGYDDKGYS---NRLYFVNLRTRDETYIWEKITDFEGQ 119 Query: 170 YPSPKAGATLVVYKDLLVLFGGW--TRPSP----YPLHQP---ERFF----DEIHTY-SP 215 P+P+ + VYKD L+ FGG+ R S + +H E+ F +++H + + Sbjct: 120 PPTPRDKLSCWVYKDRLIYFGGYGCRRHSELQDCFDVHDASWEEQIFWGWHNDVHIFDTK 179 Query: 216 SKNWWNCIVTTHGPP-PMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWS-KP 273 ++ W+ + PP P A H+ V+ +K +FGG + +M ND+ L+L+ W WS + Sbjct: 180 TQTWFQPEIKGGVPPQPRAAHTCAVLGNKGYIFGGRVLQTRM-NDLHYLNLDTWTWSGRI 238 Query: 274 NISGPSPHPRGGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVENEE 333 I+G SP R + I D + + GG N D W+ ++ + W ++ + Sbjct: 239 TINGESPKHRSWHTLTPIADDKLFLCGGLSADNIPLSDGWIHNVTTNCWK----QLTHLP 294 Query: 334 HGAPELWCHPAC 345 P LW H AC Sbjct: 295 KTRPRLW-HTAC 305 Score = 52.0 bits (123), Expect = 2e-06 Identities = 53/235 (22%), Positives = 84/235 (35%), Gaps = 36/235 (15%) Query: 133 MYVFGGCTQSSCNAAF---NDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLF 189 +YV+GG N + +++W D++S W L G P+ +G+ L +F Sbjct: 25 LYVWGGYVSIEDNEVYLPNDEIWTYDIDSGLWRMHLMEGELPASMSGSCGACINGKLYIF 84 Query: 190 GGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSC-VIDDKMIVFG 248 GG+ + +F + T + W PP SC V D++I FG Sbjct: 85 GGYDDKG----YSNRLYFVNLRTRDETYIWEKITDFEGQPPTPRDKLSCWVYKDRLIYFG 140 Query: 249 GSLGSRQMS----------------------NDVWVLDLEQWAWSKPNI-SGPSPHPRGG 285 G G R+ S NDV + D + W +P I G P PR Sbjct: 141 G-YGCRRHSELQDCFDVHDASWEEQIFWGWHNDVHIFDTKTQTWFQPEIKGGVPPQPRAA 199 Query: 286 QSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELW 340 + V+ + + GG + L +++ W W N E W Sbjct: 200 HTCAVLGNKGYIF----GGRVLQTRMNDLHYLNLDTWTWSGRITINGESPKHRSW 250 >gi|98986457 host cell factor 1 [Homo sapiens] Length = 2035 Score = 74.7 bits (182), Expect = 3e-13 Identities = 66/253 (26%), Positives = 106/253 (41%), Gaps = 45/253 (17%) Query: 133 MYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLA----SGSYPSPKAGATLVVYKDLLVL 188 + VFGG + + NDL+ L + EW R A +G P P+ G + + + L Sbjct: 94 LLVFGGMVEYGKYS--NDLYELQASRWEWKRLKAKTPKNGPPPCPRLGHSFSLVGNKCYL 151 Query: 189 FGGWTRPSPYPLHQPERFFDEIHTYS--PSKNW--WNCIVTTHG--PPPMAGHSSCVIDD 242 FGG S P + R+ ++++ P W+ I T+G PPP H++ V + Sbjct: 152 FGGLANDSEDPKNNIPRYLNDLYILELRPGSGVVAWD-IPITYGVLPPPRESHTAVVYTE 210 Query: 243 K------MIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDATI 296 K ++++GG G R D+W LD++ W+KP++SG +P PR S I + Sbjct: 211 KDNKKSKLVIYGGMSGCRL--GDLWTLDIDTLTWNKPSLSGVAPLPRSLHSATTIGNKMY 268 Query: 297 LILGGCGGPNALFKDAWLLHMHSGPW--------------AWQPLKVENEEHGAPELWCH 342 + GG L D + H W AW+ + ++ E P Sbjct: 269 VF----GGWVPLVMDDVKVATHEKEWKCTNTLACLNLDTMAWETILMDTLEDNIPR---- 320 Query: 343 PACRVGQCVVVFS 355 R G C V + Sbjct: 321 --ARAGHCAVAIN 331 Score = 65.9 bits (159), Expect = 1e-10 Identities = 44/140 (31%), Positives = 65/140 (46%), Gaps = 17/140 (12%) Query: 167 SGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTT 226 SG P P+ G V K+L+V+FGG E DE+H Y+ + N W I Sbjct: 26 SGPVPRPRHGHRAVAIKELIVVFGGGN----------EGIVDELHVYNTATNQW-FIPAV 74 Query: 227 HG--PPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAW----SKPNISGPSP 280 G PP A + +++VFGG + + SND++ L +W W +K +GP P Sbjct: 75 RGDIPPGCAAYGFVCDGTRLLVFGGMVEYGKYSNDLYELQASRWEWKRLKAKTPKNGPPP 134 Query: 281 HPRGGQSQIVIDDATILILG 300 PR G S ++ + L G Sbjct: 135 CPRLGHSFSLVGNKCYLFGG 154 Score = 53.5 bits (127), Expect = 7e-07 Identities = 44/178 (24%), Positives = 74/178 (41%), Gaps = 43/178 (24%) Query: 119 RFSHSACYY----DANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPK 174 R SH+A Y + + ++GG S C DLW LD+++ W +P SG P P+ Sbjct: 200 RESHTAVVYTEKDNKKSKLVIYGG--MSGCR--LGDLWTLDIDTLTWNKPSLSGVAPLPR 255 Query: 175 AGATLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNW--------------- 219 + + + + +FGGW PL D++ + K W Sbjct: 256 SLHSATTIGNKMYVFGGWV-----PL-----VMDDVKVATHEKEWKCTNTLACLNLDTMA 305 Query: 220 WNCI----VTTHGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSN------DVWVLDLEQ 267 W I + + P AGH + I+ ++ ++ G G R+ N D+W L+ E+ Sbjct: 306 WETILMDTLEDNIPRARAGHCAVAINTRLYIWSGRDGYRKAWNNQVCCKDLWYLETEK 363 Score = 48.9 bits (115), Expect = 2e-05 Identities = 49/210 (23%), Positives = 81/210 (38%), Gaps = 36/210 (17%) Query: 135 VFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLFGGWTR 194 VFGG + ++L + + +W P G P A V L++FGG Sbjct: 47 VFGGGNEG----IVDELHVYNTATNQWFIPAVRGDIPPGCAAYGFVCDGTRLLVFGGMVE 102 Query: 195 PSPYPLHQPERFFDEIHTYSPSKNWWNCI---VTTHGPP--PMAGHSSCVIDDKMIVFGG 249 Y ++++ S+ W + +GPP P GHS ++ +K +FGG Sbjct: 103 YGKYS--------NDLYELQASRWEWKRLKAKTPKNGPPPCPRLGHSFSLVGNKCYLFGG 154 Query: 250 SLGSRQ--------MSNDVWVLDLEQW----AWSKPNISGPSPHPRGGQSQIVIDD---- 293 + ND+++L+L AW P G P PR + +V + Sbjct: 155 LANDSEDPKNNIPRYLNDLYILELRPGSGVVAWDIPITYGVLPPPRESHTAVVYTEKDNK 214 Query: 294 -ATILILGGCGGPNALFKDAWLLHMHSGPW 322 + ++I GG G D W L + + W Sbjct: 215 KSKLVIYGGMSG--CRLGDLWTLDIDTLTW 242 >gi|7657301 kelch domain containing 2 [Homo sapiens] Length = 406 Score = 71.6 bits (174), Expect = 2e-12 Identities = 60/241 (24%), Positives = 93/241 (38%), Gaps = 28/241 (11%) Query: 124 ACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKE----WIRPLASGSYPSPKAGATL 179 +C ++ +Y+FGG N + LD S + W R G PS K + Sbjct: 94 SCAVCVDRVLYLFGG---HHSRGNTNKFYMLDSRSTDRVLQWERIDCQGIPPSSKDKLGV 150 Query: 180 VVYKDLLVLFGGW--------------TRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVT 225 VYK+ L+ FGG+ S + P + D +H W+ +T Sbjct: 151 WVYKNKLIFFGGYGYLPEDKVLGTFEFDETSFWNSSHPRGWNDHVHILDTETFTWSQPIT 210 Query: 226 T-HGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRG 284 T P P A H+ + ++ VFGG +M ND+ L+L+ W W++ G P R Sbjct: 211 TGKAPSPRAAHACATVGNRGFVFGGRYRDARM-NDLHYLNLDTWEWNELIPQGICPVGRS 269 Query: 285 GQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELWCHPA 344 S + + + GG DAW + W ++ + P LW H A Sbjct: 270 WHSLTPVSSDHLFLFGGFTTDKQPLSDAWTYCISKNEW----IQFNHPYTEKPRLW-HTA 324 Query: 345 C 345 C Sbjct: 325 C 325 Score = 50.1 bits (118), Expect = 7e-06 Identities = 49/150 (32%), Positives = 72/150 (48%), Gaps = 18/150 (12%) Query: 105 ESRTYPYP---GTPITQRFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEW 161 E+ T+ P G + R +H AC N+ +VFGG + +A NDL L+L++ EW Sbjct: 201 ETFTWSQPITTGKAPSPRAAH-ACATVGNRG-FVFGGRYR---DARMNDLHYLNLDTWEW 255 Query: 162 IRPLASGSYPSPKAGATLV-VYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWW 220 + G P ++ +L V D L LFGG+T QP + TY SKN W Sbjct: 256 NELIPQGICPVGRSWHSLTPVSSDHLFLFGGFTTDK-----QP---LSDAWTYCISKNEW 307 Query: 221 NCIVTTHGPPPMAGHSSCVIDD-KMIVFGG 249 + P H++C D+ ++IVFGG Sbjct: 308 IQFNHPYTEKPRLWHTACASDEGEVIVFGG 337 Score = 43.1 bits (100), Expect = 9e-04 Identities = 48/227 (21%), Positives = 82/227 (36%), Gaps = 44/227 (19%) Query: 133 MYVFGGCTQSSCNAAFN------DLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLL 186 M+V+GG + ++ +LW ++ + W + G P +G+ V +L Sbjct: 44 MFVWGGYKSNQVRGLYDFYLPREELWIYNMETGRWKKINTEGDVPPSMSGSCAVCVDRVL 103 Query: 187 VLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSC-VIDDKMI 245 LFGG + +F+ + W I PP V +K+I Sbjct: 104 YLFGGH-----HSRGNTNKFYMLDSRSTDRVLQWERIDCQGIPPSSKDKLGVWVYKNKLI 158 Query: 246 VFGG----------------------SLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPR 283 FGG S R ++ V +LD E + WS+P +G +P PR Sbjct: 159 FFGGYGYLPEDKVLGTFEFDETSFWNSSHPRGWNDHVHILDTETFTWSQPITTGKAPSPR 218 Query: 284 GGQSQIVIDDATILILGGCGGPNALFKDAWLLHMH---SGPWAWQPL 327 + + + + GG ++DA + +H W W L Sbjct: 219 AAHACATVGNRG-FVFGG------RYRDARMNDLHYLNLDTWEWNEL 258 >gi|7019405 host cell factor C2 [Homo sapiens] Length = 792 Score = 70.1 bits (170), Expect = 7e-12 Identities = 52/179 (29%), Positives = 76/179 (42%), Gaps = 30/179 (16%) Query: 113 GTPITQRFSHSACYYDANQS----MYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASG 168 G + R SH+A Y S MYVFGG C A +DLW+LDL + W +P G Sbjct: 184 GVVPSPRESHTAVIYCKKDSGSPKMYVFGGM----CGARLDDLWQLDLETMSWSKPETKG 239 Query: 169 SYPSPKAGATLVVYKDLLVLFGGW-------TRPSPYPLHQPERFFDEIHTYSPSKNWWN 221 + P P++ T V + + +FGGW T SP+ R + W Sbjct: 240 TVPLPRSLHTASVIGNKMYIFGGWVPHKGENTETSPHDCEW--RCTSSFSYLNLDTTEWT 297 Query: 222 CIVT-------THGPPPMAGHSSCVIDDKMIVFGG------SLGSRQMSNDVWVLDLEQ 267 +V+ P P AGH + I ++ + G +L S+ D+W LD E+ Sbjct: 298 TLVSDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSGRDGYKKALNSQVCCKDLWYLDTEK 356 Score = 64.7 bits (156), Expect = 3e-10 Identities = 54/182 (29%), Positives = 81/182 (44%), Gaps = 20/182 (10%) Query: 135 VFGGCTQSSCNAAFNDLWRLDLNSKEWIR----PLASGSYPSPKAGATLVVYKDLLVLFG 190 VFGG + + N+L+ L + W + P SG P P+ G + +Y + LFG Sbjct: 86 VFGGMVEYGRYS--NELYELQASRWLWKKVKPHPPPSGLPPCPRLGHSFSLYGNKCYLFG 143 Query: 191 GWTRPSPYPLHQPERFFDEIHT----YSPSKNWWNCIVTTHG-PPPMAGHSSCVI----- 240 G S + R+ ++ + + W+ VT P P H++ + Sbjct: 144 GLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGVVPSPRESHTAVIYCKKDS 203 Query: 241 -DDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDATILIL 299 KM VFGG G+R +D+W LDLE +WSKP G P PR + VI + + I Sbjct: 204 GSPKMYVFGGMCGARL--DDLWQLDLETMSWSKPETKGTVPLPRSLHTASVIGN-KMYIF 260 Query: 300 GG 301 GG Sbjct: 261 GG 262 Score = 59.3 bits (142), Expect = 1e-08 Identities = 38/126 (30%), Positives = 58/126 (46%), Gaps = 15/126 (11%) Query: 167 SGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKN-WWNCIVT 225 +G P + G V ++L+++FGG E DE+H Y+ + N W+ V Sbjct: 16 TGPVPRARHGHRAVAIRELMIIFGGGN----------EGIADELHVYNTATNQWFLPAVR 65 Query: 226 THGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSK----PNISGPSPH 281 PP A H +++VFGG + + SN+++ L +W W K P SG P Sbjct: 66 GDIPPGCAAHGFVCDGTRILVFGGMVEYGRYSNELYELQASRWLWKKVKPHPPPSGLPPC 125 Query: 282 PRGGQS 287 PR G S Sbjct: 126 PRLGHS 131 Score = 45.4 bits (106), Expect = 2e-04 Identities = 34/126 (26%), Positives = 54/126 (42%), Gaps = 7/126 (5%) Query: 214 SPSKNWWNCIVTTHGPPPMA--GHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWS 271 +PS W + + GP P A GH + I + MI+FGG G+ +++++ V + W Sbjct: 3 APSLLNWRRVSSFTGPVPRARHGHRAVAIRELMIIFGG--GNEGIADELHVYNTATNQWF 60 Query: 272 KPNISGPSPHPRGGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVEN 331 P + G P P V D IL+ GG + L + + W W+ +K Sbjct: 61 LPAVRGDIP-PGCAAHGFVCDGTRILVFGGMVEYGRYSNE--LYELQASRWLWKKVKPHP 117 Query: 332 EEHGAP 337 G P Sbjct: 118 PPSGLP 123 >gi|16945972 kelch domain containing 3 [Homo sapiens] Length = 382 Score = 67.4 bits (163), Expect = 4e-11 Identities = 64/248 (25%), Positives = 100/248 (40%), Gaps = 30/248 (12%) Query: 119 RFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGAT 178 R+ HS D ++ T+ +CN L+ D+N+ +W P SG+ P + G + Sbjct: 77 RYGHSTVLIDDTVLLWGGRNDTEGACNV----LYAFDVNTHKWFTPRVSGTVPGARDGHS 132 Query: 179 LVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAG-HSS 237 V ++ +FGG+ + Q + F ++IH S W I T P HS+ Sbjct: 133 ACVLGKIMYIFGGYEQ-------QADCFSNDIHKLDTSTMTWTLICTKGSPARWRDFHSA 185 Query: 238 CVIDDKMIVFGG---SLGSRQMSNDVW-----VLDLEQWAWSKPNISGPSP-HPRGGQSQ 288 ++ M VFGG G +N+++ V D AW P+P P G +S Sbjct: 186 TMLGSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEAWLD---CPPTPVLPEGRRSH 242 Query: 289 IVID-DATILILGGCGGP-NALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELWCHPACR 346 + + I GG N F D W + S W K+E + G C Sbjct: 243 SAFGYNGELYIFGGYNARLNRHFHDLWKFNPVSFTWK----KIEPKGKGPCPRRRQCCCI 298 Query: 347 VGQCVVVF 354 VG +V+F Sbjct: 299 VGDKIVLF 306 Score = 59.3 bits (142), Expect = 1e-08 Identities = 53/210 (25%), Positives = 89/210 (42%), Gaps = 7/210 (3%) Query: 113 GTPITQRFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPS 172 GT R HSAC + MY+FGG Q + + ND+ +LD ++ W GS Sbjct: 122 GTVPGARDGHSACVL--GKIMYIFGGYEQQA-DCFSNDIHKLDTSTMTWTLICTKGSPAR 178 Query: 173 PKAGATLVVYKDLLVLFGGWT-RPSPYPLHQPERFFDEIHTYSP-SKNWWNCIVTTHGPP 230 + + + + +FGG R P+ + E + + I + ++ W +C T P Sbjct: 179 WRDFHSATMLGSHMYVFGGRADRFGPFHSNN-EIYCNRIRVFDTRTEAWLDCPPTPVLPE 237 Query: 231 PMAGHSSCVIDDKMIVFGG-SLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQI 289 HS+ + ++ +FGG + + +D+W + + W K G P PR Q Sbjct: 238 GRRSHSAFGYNGELYIFGGYNARLNRHFHDLWKFNPVSFTWKKIEPKGKGPCPRRRQCCC 297 Query: 290 VIDDATILILGGCGGPNALFKDAWLLHMHS 319 ++ D +L G P D + L HS Sbjct: 298 IVGDKIVLFGGTSPSPEEGLGDEFDLIDHS 327 Score = 50.4 bits (119), Expect = 6e-06 Identities = 34/88 (38%), Positives = 45/88 (51%), Gaps = 6/88 (6%) Query: 112 PGTPITQ--RFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGS 169 P TP+ R SHSA Y N +Y+FGG + N F+DLW+ + S W + G Sbjct: 230 PPTPVLPEGRRSHSAFGY--NGELYIFGGYN-ARLNRHFHDLWKFNPVSFTWKKIEPKGK 286 Query: 170 YPSPKAGATLVVYKDLLVLFGGWTRPSP 197 P P+ + D +VLFGG T PSP Sbjct: 287 GPCPRRRQCCCIVGDKIVLFGG-TSPSP 313 >gi|21314675 kelch domain containing 4 [Homo sapiens] Length = 520 Score = 65.5 bits (158), Expect = 2e-10 Identities = 56/210 (26%), Positives = 94/210 (44%), Gaps = 31/210 (14%) Query: 114 TPITQRFSHSACYY-DANQSMYVFGGCTQSSCNAAF---NDLWRLDLNSKEWIRPLASGS 169 +P +R +H A ++VFGG S F DLW L L +K W + ++G Sbjct: 114 SPPPRRCAHQAVVVPQGGGQLWVFGGEFASPNGEQFYHYKDLWVLHLATKTWEQVKSTGG 173 Query: 170 YPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQPER---FFDEIHTYSPSKNWWNCIVTT 226 PS ++G +V +K L+LFGG+ H+ R ++++++ ++ W+ + + Sbjct: 174 -PSGRSGHRMVAWKRQLILFGGF--------HESTRDYIYYNDVYAFNLDTFTWSKLSPS 224 Query: 227 H-GPPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDV---------WVLDLE-----QWAWS 271 GP P +G V IV G +++ DV ++L E +W W+ Sbjct: 225 GTGPTPRSGCQMSVTPQGGIVVYGGYSKQRVKKDVDKGTRHSDMFLLKPEDGREDKWVWT 284 Query: 272 KPNISGPSPHPRGGQSQIVIDDATILILGG 301 + N SG P PR G S + + L GG Sbjct: 285 RMNPSGVKPTPRSGFSVAMAPNHQTLFFGG 314 Score = 56.2 bits (134), Expect = 1e-07 Identities = 47/203 (23%), Positives = 82/203 (40%), Gaps = 11/203 (5%) Query: 106 SRTYPYPGTPITQRFSHSACYYDANQSMYVFGG-CTQSSCNAAFNDLWRLDLNSKEWIRP 164 ++T P P + R + S + + +FGG +N+L+ + W + Sbjct: 51 TQTVELPCPPPSPRLNASLSVHPEKDELILFGGEYFNGQKTFLYNELYVYNTRKDTWTKV 110 Query: 165 LASGSYPSPKAGATLVVYK---DLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWN 221 P A +VV + L V G + P+ + + ++ + W Sbjct: 111 DIPSPPPRRCAHQAVVVPQGGGQLWVFGGEFASPNGEQFYH----YKDLWVLHLATKTWE 166 Query: 222 CIVTTHGPPPMAGHSSCVIDDKMIVFGGSLGSRQ---MSNDVWVLDLEQWAWSKPNISGP 278 + +T GP +GH ++I+FGG S + NDV+ +L+ + WSK + SG Sbjct: 167 QVKSTGGPSGRSGHRMVAWKRQLILFGGFHESTRDYIYYNDVYAFNLDTFTWSKLSPSGT 226 Query: 279 SPHPRGGQSQIVIDDATILILGG 301 P PR G V I++ GG Sbjct: 227 GPTPRSGCQMSVTPQGGIVVYGG 249 Score = 40.4 bits (93), Expect = 0.006 Identities = 28/92 (30%), Positives = 47/92 (51%), Gaps = 13/92 (14%) Query: 242 DKMIVFGGSLGSRQMS---NDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVI---DDAT 295 D++I+FGG + Q + N+++V + + W+K +I PSP PR Q V+ Sbjct: 76 DELILFGGEYFNGQKTFLYNELYVYNTRKDTWTKVDI--PSPPPRRCAHQAVVVPQGGGQ 133 Query: 296 ILILGG-CGGPNAL----FKDAWLLHMHSGPW 322 + + GG PN +KD W+LH+ + W Sbjct: 134 LWVFGGEFASPNGEQFYHYKDLWVLHLATKTW 165 >gi|47717139 leucine-zipper-like transcription regulator 1 [Homo sapiens] Length = 840 Score = 62.8 bits (151), Expect = 1e-09 Identities = 61/244 (25%), Positives = 95/244 (38%), Gaps = 21/244 (8%) Query: 118 QRFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGA 177 +R H+ Y ++YVFGG + NDL R D+ W R +G+ P+P+ Sbjct: 67 RRSKHTVVAY--KDAIYVFGG---DNGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHH 121 Query: 178 TLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSS 237 + VVY + +FGG+T Y + D + W + P + H + Sbjct: 122 SAVVYGSSMFVFGGYT-GDIYSNSNLKNKNDLFEYKFATGQWTEWKIEGRLPVARSAHGA 180 Query: 238 CVIDDKMIVFGGSLGSRQMSNDVWVL---DLEQWAWSKPNISGPSPHPRGGQSQIVIDDA 294 V DK+ +F G G+ ++ ND+W + D E W + SG P V D Sbjct: 181 TVYSDKLWIFAGYDGNARL-NDMWTIGLQDRELTCWEEVAQSGEIPPSCCNFPVAVCRDK 239 Query: 295 TILILGGCGG--PNALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELWCHPACRVGQCVV 352 + G G N LF+ W + E+ G+P P R G +V Sbjct: 240 MFVFSGQSGAKITNNLFQ------FEFKDKTWTRIPTEHLLRGSPP---PPQRRYGHTMV 290 Query: 353 VFSQ 356 F + Sbjct: 291 AFDR 294 Score = 53.9 bits (128), Expect = 5e-07 Identities = 54/209 (25%), Positives = 81/209 (38%), Gaps = 22/209 (10%) Query: 113 GTPITQRFSHSACYYDANQSMYVFGGCT----QSSCNAAFNDLWRLDLNSKEWIRPLASG 168 GTP R+ HSA Y SM+VFGG T +S NDL+ + +W G Sbjct: 112 GTPPAPRYHHSAVVY--GSSMFVFGGYTGDIYSNSNLKNKNDLFEYKFATGQWTEWKIEG 169 Query: 169 SYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHG 228 P ++ VY D L +F G+ + D T W + Sbjct: 170 RLPVARSAHGATVYSDKLWIFAGYDGNARLNDMWTIGLQDRELTC-----WEEVAQSGEI 224 Query: 229 PPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNI------SGPSPHP 282 PP V DKM VF G G++ ++N+++ + + W++ S P P Sbjct: 225 PPSCCNFPVAVCRDKMFVFSGQSGAK-ITNNLFQFEFKDKTWTRIPTEHLLRGSPPPPQR 283 Query: 283 RGGQSQIVIDDATILILGGCGG---PNAL 308 R G + + D + + GG PN L Sbjct: 284 RYGHTMVAF-DRHLYVFGGAADNTLPNEL 311 >gi|195963410 MEF2 activating motif and SAP domain containing transcriptional regulator isoform 1 [Homo sapiens] Length = 415 Score = 58.2 bits (139), Expect = 3e-08 Identities = 80/264 (30%), Positives = 110/264 (41%), Gaps = 39/264 (14%) Query: 363 PLSPSLNSRPSPISATPPALVPETREYRSQSPVRS-MDEAPCVNGRWGTLRPRA----QR 417 PL+P+L S +P +P L+PE EY P RS E+P ++ RW +PR + Sbjct: 46 PLAPALPSGTAPFLFSPGVLLPEP-EY--CPPWRSPKKESPKISQRWRESKPRGNLTYHQ 102 Query: 418 QTPSGSREGSLSPARGDGSPI-LNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDL 476 P R+GS + + +GS + G SL GT S P SP TP P G Sbjct: 103 YMPPEPRQGSRADPQAEGSALGPPGPSLWEGT----DSQQPHPRMKPSPLTP-CPPGVP- 156 Query: 477 KIGLSLAPRRGSLPDQKDLRLGSIDLNWDLK----PASSSNPMDGMDNRTVGGSMRHPPE 532 S P + L K L +L L+ P S + M + R GG+ PP Sbjct: 157 --SPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSM--LLERMRGGA---PPR 209 Query: 533 QTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQS 592 + P + AGA P ++L A + S PSA A+ PPL + +PG Sbjct: 210 E----RPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSA-ASHRPPLPRAADTPG--- 261 Query: 593 LSSGETVPIPRPGPAQGDGHSLPP 616 T P P P PA +L P Sbjct: 262 -----TAPAPTPTPAPAAAPALTP 280 Score = 32.7 bits (73), Expect = 1.2 Identities = 72/269 (26%), Positives = 95/269 (35%), Gaps = 46/269 (17%) Query: 273 PNISGPSPHPRGGQSQIV-IDDATILILGGC----GGPNALFKDAWLLHMHSGPWAWQPL 327 P + PSP P + Q + +++ T+ L G P + K L M G + Sbjct: 153 PGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERP 212 Query: 328 KVENEEHGAPELWCH-------PACRVGQCVVVFSQAPSGRAPLSPSLNS-------RPS 373 K E+ A W A R G V A S R PL + ++ P+ Sbjct: 213 KPRREDSPAGAPWPRLKPKALAAARRQGS---VKPSAASHRPPLPRAADTPGTAPAPTPT 269 Query: 374 PISATPPALVPE--------TREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSGSRE 425 P A PAL P T E Q +R P G L + + P Sbjct: 270 PAPAAAPALTPSSGPGSAALTLEEELQEAIRRAQLLPN-RGIDDILEDQVEPDDP----- 323 Query: 426 GSLSPARGD--GS-PILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGLSL 482 L P D GS +L+ S G ++V SSL SP + SPS + D LS Sbjct: 324 --LPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDPTDSLDWLEALSG 381 Query: 483 APRRGSLPD-----QKDLRLGSIDLNWDL 506 P GS P DL S WDL Sbjct: 382 GPPLGSGPPPPSIFSADLSDSSSSRLWDL 410 >gi|145701025 multiple EGF-like-domains 8 [Homo sapiens] Length = 2778 Score = 55.8 bits (133), Expect = 1e-07 Identities = 73/277 (26%), Positives = 109/277 (39%), Gaps = 48/277 (17%) Query: 113 GTPITQRFSHSACYYDANQSMYVFGGCT-QSSCNAAFNDLWRLDLNSKEWIRPLASGSYP 171 GTP T + HSA Y++A S+YVFGG A +L+ L + W S Sbjct: 1599 GTPPTGLYGHSAVYHEATDSLYVFGGFRFHVELAAPSPELYSLHCPDRTW-------SLL 1651 Query: 172 SPKAGATLVVYKDLLVLFGGWTRP-SPYPLHQPERF-FDEIHTYSPSKNWWNCIVTTHG- 228 +P GA +D + G +R P QP + F E+ W + T G Sbjct: 1652 APSQGAK----RDRMRNVRGSSRGLGQVPGEQPGSWGFREVR---KKMALWAALAGTGGF 1704 Query: 229 ----------PPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNIS-- 276 P P H+S ++ D M+V GG + S+DV + + AW P+++ Sbjct: 1705 LEEISPHLKEPRPRLFHASALLGDTMVVLGGRSDPDEFSSDVLLYQVNCNAWLLPDLTRS 1764 Query: 277 ---GPSPHPRGGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVENEE 333 GP P + + + I GG GG AL + LL + P P ++ + Sbjct: 1765 ASVGP-PMEESVAHAVAAVGSRLYISGGFGGV-ALGR---LLALTLPP---DPCRLLSSP 1816 Query: 334 HGAPE----LWCHPACRVGQCVVVFSQAPSGRAPLSP 366 + WCH AC G + G +P SP Sbjct: 1817 EACNQSGACTWCHGACLSGDQA---HRLGCGGSPCSP 1850 Score = 40.0 bits (92), Expect = 0.008 Identities = 32/140 (22%), Positives = 53/140 (37%), Gaps = 22/140 (15%) Query: 166 ASGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVT 225 A+G++ SP LL +FGG ++ Y+ S N W Sbjct: 231 AAGAFLSPPG---------LLAVFGG---------QDLNNALGDLVLYNFSANTWESWDL 272 Query: 226 THGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLD-LEQWAW---SKPNISGPSPH 281 + P H + +++ GG L ++NDVW L + W + P S P Sbjct: 273 SPAPAARHSHVAVAWAGSLVLMGGELADGSLTNDVWAFSPLGRGHWELLAPPASSSSGPP 332 Query: 282 PRGGQSQIVIDDATILILGG 301 G + ++DD + + GG Sbjct: 333 GLAGHAAALVDDVWLYVSGG 352 Score = 35.8 bits (81), Expect = 0.14 Identities = 46/203 (22%), Positives = 77/203 (37%), Gaps = 25/203 (12%) Query: 122 HSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKE-WIRPLASGSYPSPKAGATLV 180 H+A D + +YV GG T ++ +RLD S W + + +G P G ++V Sbjct: 337 HAAALVD-DVWLYVSGGRTPHDLFSSGLFRFRLDSTSGGYWEQVIPAGGRPPAATGHSMV 395 Query: 181 VYK-DLLVLFGGWTRPSP----YPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGH 235 + +L G RPS ++ E F + H ++ K GP A H Sbjct: 396 FHAPSRALLVHGGHRPSTARFSVRVNSTELFHVDRHVWTTLKGRDGL----QGPRERAFH 451 Query: 236 SSCVIDDKMIVFGGSLGSRQMSNDV--------------WVLDLEQWAWSKPNISGPSPH 281 ++ V+ + M+V+GG++ + WV E P P Sbjct: 452 TASVLGNYMVVYGGNVHTHYQEEKCYEDGIFFYHLGCHQWVSGAELAPPGTPEGRAAPPS 511 Query: 282 PRGGQSQIVIDDATILILGGCGG 304 R V+ + +L+ GG G Sbjct: 512 GRYSHVAAVLGGSVLLVAGGYSG 534 Score = 33.9 bits (76), Expect = 0.54 Identities = 36/159 (22%), Positives = 63/159 (39%), Gaps = 19/159 (11%) Query: 174 KAGATLVVYKDL-LVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTH----- 227 + G T+V D L +FGG L P+ ++ YS S+ W ++ Sbjct: 1443 RLGHTMVDGPDATLWMFGG--------LGLPQGLLGNLYRYSVSERRWTQMLAGAEDGGP 1494 Query: 228 GPPPMAGHSSCVID---DKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPR- 283 GP P + H++ + M + GG L + ++ D WVL+L W + P Sbjct: 1495 GPSPRSFHAAAYVPAGRGAMYLLGG-LTAGGVTRDFWVLNLTTLQWRQEKAPQTVELPAV 1553 Query: 284 GGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPW 322 G + ++L++GG N + + +G W Sbjct: 1554 AGHTLTARRGLSLLLVGGYSPENGFNQQLLEYQLATGTW 1592 >gi|33695109 Rab9 effector protein with kelch motifs [Homo sapiens] Length = 372 Score = 55.5 bits (132), Expect = 2e-07 Identities = 42/149 (28%), Positives = 65/149 (43%), Gaps = 14/149 (9%) Query: 105 ESRTYPYP---GTPITQRFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEW 161 E+RT+ P P + R H++ NQ +YVFGG + + L D N+ W Sbjct: 122 ETRTWTTPEVTSPPPSPRTFHTSSAAIGNQ-LYVFGGGERGAQPVQDTKLHVFDANTLTW 180 Query: 162 IRPLASGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWN 221 +P G+ PSP+ G +V L + GG +RF+D++H S W Sbjct: 181 SQPETLGNPPSPRHGHVMVAAGTKLFIHGGLA---------GDRFYDDLHCIDISDMKWQ 231 Query: 222 CIVTTHGPPP-MAGHSSCVIDDKMIVFGG 249 + T P A HS+ + + +FGG Sbjct: 232 KLNPTGAAPAGCAAHSAVAMGKHVYIFGG 260 Score = 54.3 bits (129), Expect = 4e-07 Identities = 68/268 (25%), Positives = 100/268 (37%), Gaps = 37/268 (13%) Query: 108 TYPYPGTPITQRFSHSACYYDA-----NQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWI 162 T PG R HS Y +++ GG N +F+D+ +DL +W Sbjct: 20 TLTVPGDSPCARVGHSCSYLPPVGNAKRGKVFIVGGANP---NRSFSDVHTMDLGKHQWD 76 Query: 163 RPLASGSYPSPKAGATL-VVYKDLLVLFGGWTRPSPYPLHQ---PERFFDEIHTYSPSKN 218 G P + + + D + +FGG + Q PE ++ Sbjct: 77 LDTCKGLLPRYEHASFIPSCTPDRIWVFGGANQSGNRNCLQVLNPE-----------TRT 125 Query: 219 WWNCIVTTHGPPPMAGH-SSCVIDDKMIVFGGSLGSRQMSND--VWVLDLEQWAWSKPNI 275 W VT+ P P H SS I +++ VFGG Q D + V D WS+P Sbjct: 126 WTTPEVTSPPPSPRTFHTSSAAIGNQLYVFGGGERGAQPVQDTKLHVFDANTLTWSQPET 185 Query: 276 SGPSPHPRGGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEHG 335 G P PR G +V + I GG G + + D + + WQ L G Sbjct: 186 LGNPPSPRHGH-VMVAAGTKLFIHGGLAG-DRFYDDLHCIDI--SDMKWQKL----NPTG 237 Query: 336 APELWC--HPACRVGQCVVVF-SQAPSG 360 A C H A +G+ V +F P+G Sbjct: 238 AAPAGCAAHSAVAMGKHVYIFGGMTPAG 265 Score = 53.9 bits (128), Expect = 5e-07 Identities = 58/234 (24%), Positives = 93/234 (39%), Gaps = 21/234 (8%) Query: 100 GNIQWESRTYPYPGTPITQRFSHSACYYDANQS-MYVFGGCTQSSCNAAFNDLWRLDLNS 158 G QW+ T + R+ H++ ++VFGG QS N L L+ + Sbjct: 71 GKHQWDLDTCK----GLLPRYEHASFIPSCTPDRIWVFGGANQSGNR---NCLQVLNPET 123 Query: 159 KEWIRPLASGSYPSPKAGATL-VVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSK 217 + W P + PSP+ T + L +FGG R + QP + ++H + + Sbjct: 124 RTWTTPEVTSPPPSPRTFHTSSAAIGNQLYVFGGGERGA-----QPVQD-TKLHVFDANT 177 Query: 218 NWWNCIVTTHGPP-PMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNIS 276 W+ T PP P GH K+ + GG G R +D+ +D+ W K N + Sbjct: 178 LTWSQPETLGNPPSPRHGHVMVAAGTKLFIHGGLAGDR-FYDDLHCIDISDMKWQKLNPT 236 Query: 277 GPSPHPRGGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVE 330 G +P S + + + I GG AL + H+ W LK + Sbjct: 237 GAAPAGCAAHSAVAM-GKHVYIFGGMTPAGAL---DTMYQYHTEEQHWTLLKFD 286 >gi|44917619 kelch domain containing 10 [Homo sapiens] Length = 442 Score = 54.3 bits (129), Expect = 4e-07 Identities = 52/186 (27%), Positives = 82/186 (44%), Gaps = 23/186 (12%) Query: 130 NQSMYVFGGCTQSSCNAA---------FNDLWRLDLNSKEWIRPLASGSYPSPKAGATLV 180 N ++YVFGG + F +LWR + W + G P A +LV Sbjct: 101 NTNLYVFGGYNPDYDESGGPDNEDYPLFRELWRYHFATGVWHQMGTDGYMPRELASMSLV 160 Query: 181 VYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPP--MAGHSSC 238 ++ + L++FGG P E +++H + W +++ G P + G + Sbjct: 161 LHGNNLLVFGGTGIPF------GESNGNDVHVCNVKYKRW-ALLSCRGKKPSRIYGQAMA 213 Query: 239 VIDDKMIVFGGSLGSRQMSNDVWVLDL--EQWAWSKP-NISGPSPHPRGGQSQIVIDDAT 295 +I+ + VFGG+ G S D+ LDL +W KP N+S P R + +I D Sbjct: 214 IINGSLYVFGGTTG-YIYSTDLHKLDLNTREWTQLKPNNLSCDLPEER-YRHEIAHDGQR 271 Query: 296 ILILGG 301 I ILGG Sbjct: 272 IYILGG 277 Score = 53.1 bits (126), Expect = 9e-07 Identities = 46/159 (28%), Positives = 70/159 (44%), Gaps = 19/159 (11%) Query: 130 NQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEW--IRPL-ASGSYPSPKAGATLVVYKDLL 186 N S+YVFGG T + DL +LDLN++EW ++P S P + + + Sbjct: 216 NGSLYVFGGTTGYIYST---DLHKLDLNTREWTQLKPNNLSCDLPEERYRHEIAHDGQRI 272 Query: 187 VLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHG-----PPPMAGHSSCVID 241 + GG T + Y L++ IH Y+ N W I T P HS I Sbjct: 273 YILGGGTSWTAYSLNK-------IHAYNLETNAWEEIATKPHEKIGFPAARRCHSCVQIK 325 Query: 242 DKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSP 280 + + + GG G + D+W L+L+ + W K + P P Sbjct: 326 NDVFICGGYNGE-VILGDIWKLNLQTFQWVKLPATMPEP 363 Score = 37.7 bits (86), Expect = 0.037 Identities = 46/200 (23%), Positives = 77/200 (38%), Gaps = 13/200 (6%) Query: 171 PSPKAGATLVVYKDLLVLFGGWTRP---SPYPLHQPERFFDEIHTYSPSKNWWNCIVTT- 226 P ++G V L +FGG+ S P ++ F E+ Y + W+ + T Sbjct: 89 PPARSGHRCVADNTNLYVFGGYNPDYDESGGPDNEDYPLFRELWRYHFATGVWHQMGTDG 148 Query: 227 HGPPPMAGHSSCVIDDKMIVFGGS---LGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPR 283 + P +A S + + ++VFGG+ G NDV V +++ W+ + G P Sbjct: 149 YMPRELASMSLVLHGNNLLVFGGTGIPFGESN-GNDVHVCNVKYKRWALLSCRGKKPSRI 207 Query: 284 GGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEHGAP-ELWCH 342 GQ+ +I+ + + GG L + W LK N P E + H Sbjct: 208 YGQAMAIINGSLYVF----GGTTGYIYSTDLHKLDLNTREWTQLKPNNLSCDLPEERYRH 263 Query: 343 PACRVGQCVVVFSQAPSGRA 362 GQ + + S A Sbjct: 264 EIAHDGQRIYILGGGTSWTA 283 >gi|20143482 melanoma antigen family E, 1 [Homo sapiens] Length = 957 Score = 50.4 bits (119), Expect = 6e-06 Identities = 78/299 (26%), Positives = 101/299 (33%), Gaps = 43/299 (14%) Query: 343 PACRVGQCVVVFSQAPSGRAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAP 402 P G C V A GR SRP S P VP T S V S P Sbjct: 118 PTISKGLCTSVTLAASEGRN------TSRPPTSSEEPSTSVPPTA-----SEVPSTSLPP 166 Query: 403 CVNGRWGTLRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAA--VGGSSLDSPV 460 T P + PS S + P G + +L PGT+ L + V Sbjct: 167 TPGEGTSTSVPPTAYEGPSTSVVPT--PDEGPSTSVLPTPGEGPGTSVPLAATEGLSTSV 224 Query: 461 QAI---SPST---PSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNP 514 QA PST P+A EG + + P R P + + PA+S Sbjct: 225 QATPDEGPSTSVPPTATEG----LSTPVPPTRDEGPSTSVPATPGEGPSTSVLPAASDGQ 280 Query: 515 MDGM-DNRTVGGSMRHPPEQTNGVHT--------------PPHVASALAGAVSPGALRRS 559 + R G S PP T G+ T PP L+ +V P A Sbjct: 281 SISLVPTRGKGSSTSVPPTATEGLSTSVQPTAGEGSSTSVPPTPGGGLSTSVPPTATEEL 340 Query: 560 LEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVPIPRPGPAQGDGHSLPPIA 618 ++ +GPS S P G S P + S S +VP P P +G + P A Sbjct: 341 STSVPPTPGEGPSTSVLPIPGEGLSTSVPPTASDGSDTSVP---PTPGEGASTLVQPTA 396 >gi|46410931 attractin-like 1 [Homo sapiens] Length = 1379 Score = 50.1 bits (118), Expect = 7e-06 Identities = 45/183 (24%), Positives = 82/183 (44%), Gaps = 14/183 (7%) Query: 87 HQCYHGFMKAVQEGNIQWESRTYPYP---GTPITQRFSHSACYYDANQSMYVFGGCTQSS 143 + +G+ ++QE +I S T+ P G + + H++ Y + +S+YV GG Sbjct: 434 YSAIYGYTSSIQEYHIS--SNTWLVPETKGAIVQGGYGHTSVYDEITKSIYVHGGYKALP 491 Query: 144 CN--AAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLH 201 N +DL++ ++N+K W SG + + V+ +++FGG T + Sbjct: 492 GNKYGLVDDLYKYEVNTKTWTILKESGF---ARYLHSAVLINGAMLIFGGNTHNDTSLSN 548 Query: 202 QPERFFDEIHTYSPSKNWWNCIV--TTHGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSND 259 + F + Y + + W + H GHS+ VI+ M +FGG S + ND Sbjct: 549 GAKCFSADFLAYDIACDEWKILPKPNLHRDVNRFGHSAVVINGSMYIFGGF--SSVLLND 606 Query: 260 VWV 262 + V Sbjct: 607 ILV 609 Score = 41.2 bits (95), Expect = 0.003 Identities = 41/191 (21%), Positives = 78/191 (40%), Gaps = 25/191 (13%) Query: 149 NDLWR-----LDLNSKE--WIRPLASGSYPSP-KAGATLVVYKDLLVLFGGWTRPSPYPL 200 ND W+ L++ S E WI P PS +A V++ + + GG+T Sbjct: 272 NDSWQGPDCSLNVPSTESYWILPNVKPFSPSVGRASHKAVLHGKFMWVIGGYTFNYSS-- 329 Query: 201 HQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVIDDKMIVFGGSLGSR--QMSN 258 F + Y+ + WN + GP GHS + + + ++GG + + +++ Sbjct: 330 ------FQMVLNYNLESSIWNVGTPSRGPLQRYGHSLALYQENIFMYGGRIETNDGNVTD 383 Query: 259 DVWVLDLEQWAWS--KPNISG-PSPHPRGGQSQIVID----DATILILGGCGGPNALFKD 311 ++WV ++ +WS P + G + G S +++ D ++I+ G Sbjct: 384 ELWVFNIHSQSWSTKTPTVLGHGQQYAVEGHSAHIMELDSRDVVMIIIFGYSAIYGYTSS 443 Query: 312 AWLLHMHSGPW 322 H+ S W Sbjct: 444 IQEYHISSNTW 454 Score = 32.0 bits (71), Expect = 2.0 Identities = 15/52 (28%), Positives = 29/52 (55%), Gaps = 5/52 (9%) Query: 113 GTPIT---QRFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEW 161 GTP QR+ HS Y N ++++GG +++ ++LW +++S+ W Sbjct: 346 GTPSRGPLQRYGHSLALYQEN--IFMYGGRIETNDGNVTDELWVFNIHSQSW 395 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 49.7 bits (117), Expect = 9e-06 Identities = 69/284 (24%), Positives = 103/284 (36%), Gaps = 31/284 (10%) Query: 357 APSGRAPLSPSLNSRPSPISATPPALV--PETREYRSQSPVRSMDEAPCVNGR-WGTLRP 413 +P G P +PS P+P + TPP+ P + + P G T P Sbjct: 995 SPKG-GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLP 1053 Query: 414 RAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGT---AAVGGSSLDSPVQAISP--STP 468 + TP+ + SP G +P L G P + GG + SP A P +TP Sbjct: 1054 KGAPTTPAATLP---SPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATP 1110 Query: 469 SAPEGYDLKIGLSLAPRRGSL-------PDQKDLRLGSIDLNWDLKPASSS-NPMDGMDN 520 +P+G GL+ P +G+ P K PA++ +P G+ Sbjct: 1111 PSPKG-----GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT 1165 Query: 521 RTVGGS----MRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAA 576 G+ PP G+ TP + A +P + + L + A+ Sbjct: 1166 PPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1225 Query: 577 LSPPLGSSPGSPGSQSLSSGETVPIPRPGPA--QGDGHSLPPIA 618 SP G + SP + T P P+ GPA G PP A Sbjct: 1226 PSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAA 1269 Score = 47.4 bits (111), Expect = 5e-05 Identities = 66/273 (24%), Positives = 102/273 (37%), Gaps = 45/273 (16%) Query: 357 APSGRAPLSPSLNSRPSPISATPPALVPE----TREYRSQSPVRSMDEAPCVNGRWGTLR 412 +P G P +PS P P +ATPP+ P+ T ++ +P P G T Sbjct: 1089 SPKG-GPATPSPKGAPMPPAATPPS--PKGGLATPPHKG-APTTPAATPPSPKGGLATPP 1144 Query: 413 PRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGT---AAVGGSSLDSPVQAISP--ST 467 P+ TP+ + SP G +P G +P + GG + SP A + +T Sbjct: 1145 PKGAPTTPAATPP---SPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1201 Query: 468 PSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGS- 526 P +P+G GL+ +G+ A+ +P G+ + G+ Sbjct: 1202 PPSPKG-----GLATPSPKGAPTTPA---------------ATPPSPKGGLATPSPKGAP 1241 Query: 527 ---MRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGS 583 PP G TPP + A +P +L+ L KG A ++PP S Sbjct: 1242 TTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGL---ATPPHKGAPNPAVVTPP--S 1296 Query: 584 SPGSPGSQSLSSGETVPIPRPGPAQGDGHSLPP 616 G P + T P P +G + PP Sbjct: 1297 PKGGPATSPPKGAPTPPAATPPSPKGSPGTPPP 1329 Score = 45.4 bits (106), Expect = 2e-04 Identities = 64/268 (23%), Positives = 91/268 (33%), Gaps = 23/268 (8%) Query: 357 APSGRAPLSPSLNSRPSPISATPPALV--PETREYRSQSPVRSMDEAPCVNGRWGTLRPR 414 AP G P SPS P+P +ATPP+ P T + +P P G T P+ Sbjct: 926 APKG-IPASPSPKGAPTPPAATPPSPKGGPATPSPK-WAPTPPAATPPSPKGGPATPSPK 983 Query: 415 AQRQTPSGSREGSLSPARGDGSPILNGGSLSPGT----------AAVGGSSLDSPVQAIS 464 P+ + SP G +P G P A +P A Sbjct: 984 GAPTPPAATPP---SPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATP 1040 Query: 465 PSTPSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSS-NPMDGMDNRTV 523 PS +P L G P +LP K PA++ +P G + Sbjct: 1041 PSPKGSPAATPLPKGAPTTPA-ATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP 1099 Query: 524 GGS----MRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSP 579 G+ PP G+ TPPH + A +P + + L + A+ SP Sbjct: 1100 KGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1159 Query: 580 PLGSSPGSPGSQSLSSGETVPIPRPGPA 607 G + P + T P P+ G A Sbjct: 1160 KGGLATPPPKGAPTTPAATPPSPKGGLA 1187 Score = 39.3 bits (90), Expect = 0.013 Identities = 63/276 (22%), Positives = 99/276 (35%), Gaps = 43/276 (15%) Query: 362 APLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPS 421 AP +PS S +++PPA+ P T Y+ + + P V P TP Sbjct: 1570 APATPS-----SKEASSPPAVTPST--YKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPP 1622 Query: 422 GSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGLS 481 SP +G +P G SP V SSL +P++P K+G + Sbjct: 1623 -------SPEKGPATPAPKGTPTSP---PVTPSSLKD--------SPTSPASVTCKMGAT 1664 Query: 482 LAPRRGSLPDQKDLRLGSIDLNWDL-KPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTP 540 + LP +K G L L PA S P+ R + P + + +P Sbjct: 1665 VPQASKGLPAKK----GPTALKEVLVAPAPESTPIITAPTR------KGPQTKKSSATSP 1714 Query: 541 PHVASALAGAVSPGALRR-------SLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSL 593 P A S G L ++ + ++KG AS + PL + Sbjct: 1715 PICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLT 1774 Query: 594 SSGETVPIPRPGPAQGDGHSLPPIARRLGHHPPQSL 629 ++ +P+P A PP++ L P +L Sbjct: 1775 AAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTL 1810 Score = 35.8 bits (81), Expect = 0.14 Identities = 74/296 (25%), Positives = 111/296 (37%), Gaps = 37/296 (12%) Query: 354 FSQAPSGRAPLSPSLNSRPSPISA-TPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLR 412 + APS + L P + PSP A TPPA+ P S ++ P GT Sbjct: 1590 YKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPP-----------SPEKGPATPAPKGT-- 1636 Query: 413 PRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPG-TAAVGGSSLDSPVQAISP-STP-- 468 P + TPS ++ SPA S G A G ++L + A +P STP Sbjct: 1637 PTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPII 1696 Query: 469 SAP--EGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGS 526 +AP +G K + +P P K+ G + + PA G Sbjct: 1697 TAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLS---TVAPAPLLPVQKDSSKTAKGKD 1753 Query: 527 MRHPPEQTNGVHTPPH--VASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSP-PLGS 583 H P+ G PP ++ L A L + E+ ++ P S L+P P+ + Sbjct: 1754 ASHSPK---GPLAPPESKASTPLTAAAFEKVLPKP-ESASVSAAPSPPVSLPLAPSPVPT 1809 Query: 584 SPGSPGSQSLSSGETVPIPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKPLYQSM 639 P S G + P A D L P+ PP+ ++ G P +QS+ Sbjct: 1810 LPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLI------PPEPISGGVP-FQSV 1858 Score = 33.9 bits (76), Expect = 0.54 Identities = 63/269 (23%), Positives = 100/269 (37%), Gaps = 38/269 (14%) Query: 357 APSGRAPLSPSLNSRPSPISATPPALVP--ETREYRSQSPVRSMDEAPCVNGRWGTLRPR 414 +P G P +P P+P +ATPP+L T ++ +P ++ P G T P+ Sbjct: 1250 SPKG-GPATPPPKGAPTPPAATPPSLKGGLATPPHKG-APNPAVVTPPSPKGGPATSPPK 1307 Query: 415 AQRQTPSGSREGSLSPARGDGSPILNGGSLSPGT---AAVGGSSLDS--PVQAISPSTPS 469 P+ + SP G+P G P + G +L + P P+TPS Sbjct: 1308 GAPTPPAATPP---SPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPS 1364 Query: 470 APEGY-------DLKIGLSL---APRRG-SLPDQKDLRLGSIDLNWDLKPASSSNPMDGM 518 + EG K G ++ +P+RG ++P K + K A ++ P+ Sbjct: 1365 SKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPAT-PVTRE 1423 Query: 519 DNRTVGGSMRHPPEQTN-GVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAAL 577 T PP T + P ++ G +P SSKG A+ Sbjct: 1424 GAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATP-------------SSKGDPTLPAV 1470 Query: 578 SPPLGSSPGSPGSQSLSSGETVPIPRPGP 606 +PP P +P + SS P P Sbjct: 1471 TPPSPKEPPAPKQVATSSSPKKAPATPAP 1499 >gi|21450863 attractin isoform 2 [Homo sapiens] Length = 1272 Score = 47.8 bits (112), Expect = 4e-05 Identities = 44/186 (23%), Positives = 83/186 (44%), Gaps = 10/186 (5%) Query: 87 HQCYHGFMKAVQEGNIQWESRTYPYP-GTPITQRFSHSACYYDANQSMYVFGGCTQSSCN 145 H +G++ VQE ++ + + + G + + HS+ Y +++YV GG S N Sbjct: 467 HCPLYGYISNVQEYDLDKNTWSILHTQGALVQGGYGHSSVYDHRTRALYVHGGYKAFSAN 526 Query: 146 --AAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQP 203 +DL+R D++++ W S + + T V+ +++FGG T H Sbjct: 527 KYRLADDLYRYDVDTQMWTILKDSRFF---RYLHTAVIVSGTMLVFGGNTHNDTSMSHGA 583 Query: 204 ERFFDEIHTYSPSKNWWNCI--VTTHGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVW 261 + F + Y + + W+ + H GHS+ + + M VFGG + + +D+ Sbjct: 584 KCFSSDFMAYDIACDRWSVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGF--NSLLLSDIL 641 Query: 262 VLDLEQ 267 V EQ Sbjct: 642 VFTSEQ 647 Score = 32.0 bits (71), Expect = 2.0 Identities = 37/162 (22%), Positives = 69/162 (42%), Gaps = 13/162 (8%) Query: 133 MYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLFGGW 192 M+V GG + ++ +N + DL S+EW+ S + + G +L +YKD + ++GG Sbjct: 353 MWVVGGYMFN--HSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALYKDKIYMYGGK 410 Query: 193 TRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVIDDK-----MIVF 247 + ++ F IH +++W + GHS+ ++ K M+V Sbjct: 411 IDSTGNVTNELRVF--HIH----NESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVVMLVI 464 Query: 248 GGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQI 289 G ++V DL++ WS + G G S + Sbjct: 465 FGHCPLYGYISNVQEYDLDKNTWSILHTQGALVQGGYGHSSV 506 Score = 30.4 bits (67), Expect = 6.0 Identities = 23/92 (25%), Positives = 35/92 (38%) Query: 231 PMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIV 290 P A H + V + M V GG + + N V DL W N S + R G S + Sbjct: 340 PRASHKAVVNGNIMWVVGGYMFNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLAL 399 Query: 291 IDDATILILGGCGGPNALFKDAWLLHMHSGPW 322 D + G + + + H+H+ W Sbjct: 400 YKDKIYMYGGKIDSTGNVTNELRVFHIHNESW 431 >gi|21450861 attractin isoform 1 [Homo sapiens] Length = 1429 Score = 47.8 bits (112), Expect = 4e-05 Identities = 44/186 (23%), Positives = 83/186 (44%), Gaps = 10/186 (5%) Query: 87 HQCYHGFMKAVQEGNIQWESRTYPYP-GTPITQRFSHSACYYDANQSMYVFGGCTQSSCN 145 H +G++ VQE ++ + + + G + + HS+ Y +++YV GG S N Sbjct: 467 HCPLYGYISNVQEYDLDKNTWSILHTQGALVQGGYGHSSVYDHRTRALYVHGGYKAFSAN 526 Query: 146 --AAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQP 203 +DL+R D++++ W S + + T V+ +++FGG T H Sbjct: 527 KYRLADDLYRYDVDTQMWTILKDSRFF---RYLHTAVIVSGTMLVFGGNTHNDTSMSHGA 583 Query: 204 ERFFDEIHTYSPSKNWWNCI--VTTHGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVW 261 + F + Y + + W+ + H GHS+ + + M VFGG + + +D+ Sbjct: 584 KCFSSDFMAYDIACDRWSVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGF--NSLLLSDIL 641 Query: 262 VLDLEQ 267 V EQ Sbjct: 642 VFTSEQ 647 Score = 32.0 bits (71), Expect = 2.0 Identities = 37/162 (22%), Positives = 69/162 (42%), Gaps = 13/162 (8%) Query: 133 MYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLFGGW 192 M+V GG + ++ +N + DL S+EW+ S + + G +L +YKD + ++GG Sbjct: 353 MWVVGGYMFN--HSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALYKDKIYMYGGK 410 Query: 193 TRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVIDDK-----MIVF 247 + ++ F IH +++W + GHS+ ++ K M+V Sbjct: 411 IDSTGNVTNELRVF--HIH----NESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVVMLVI 464 Query: 248 GGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQI 289 G ++V DL++ WS + G G S + Sbjct: 465 FGHCPLYGYISNVQEYDLDKNTWSILHTQGALVQGGYGHSSV 506 Score = 30.4 bits (67), Expect = 6.0 Identities = 23/92 (25%), Positives = 35/92 (38%) Query: 231 PMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIV 290 P A H + V + M V GG + + N V DL W N S + R G S + Sbjct: 340 PRASHKAVVNGNIMWVVGGYMFNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLAL 399 Query: 291 IDDATILILGGCGGPNALFKDAWLLHMHSGPW 322 D + G + + + H+H+ W Sbjct: 400 YKDKIYMYGGKIDSTGNVTNELRVFHIHNESW 431 >gi|146219832 myosin light chain kinase 3 [Homo sapiens] Length = 819 Score = 45.1 bits (105), Expect = 2e-04 Identities = 57/239 (23%), Positives = 88/239 (36%), Gaps = 44/239 (18%) Query: 391 SQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAA 450 ++ P +A + G L P + + +SP +GDG P P A Sbjct: 184 AREPGEESQKADVLEGTAERLPPIRASGLGADPAQAVVSPGQGDGVP-------GPAQAF 236 Query: 451 VGGSSLDSPVQAISPSTPSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKP-- 508 G L + V+A +P TPS +L+ GL LAP G R+ + + ++ P Sbjct: 237 PGHLPLPTKVEAKAPETPSE----NLRTGLELAPAPG--------RVNVVSPSLEVAPGA 284 Query: 509 ---ASSS----NPMDGMDNRTVGGSMRHP-----PEQTNGVH----TPPHVASALAGAVS 552 ASSS P++ T G + P P Q H TPP ++ + + Sbjct: 285 GQGASSSRPDPEPLEEGTRLTPGPGPQCPGPPGLPAQARATHSGGETPPRISIHIQEMDT 344 Query: 553 PGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVPIPRPGPAQGDG 611 PG + + S GP+ + P + PG G P PG +G Sbjct: 345 PGEM-----LMTGRGSLGPTLTT--EAPAAAQPGKQGPPGTGRCLQAPGTEPGEQTPEG 396 >gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] Length = 2752 Score = 44.3 bits (103), Expect = 4e-04 Identities = 72/284 (25%), Positives = 102/284 (35%), Gaps = 32/284 (11%) Query: 359 SGRAPLSP--SLNSRPSPI------SATPPALVPETR--EYRSQSPVRSMDEAPCVNGRW 408 S R PLS ++ R SP S TPP+ ++R R+ SP M +AP + Sbjct: 2382 SPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQS--- 2438 Query: 409 GTLRPRAQRQTPSGSREGSLSPAR---GDGSPILNGGSLSPGTAAVGGSSLDSPVQAISP 465 L P AQ Q S +R +P+ SLS G A SS +S Sbjct: 2439 --LLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSV 2496 Query: 466 STPSAPEGY----DLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNR 521 P P G +L K+ R S + +SSS+ + Sbjct: 2497 PAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSS 2556 Query: 522 ------TVGGSMRHPPEQT-NGVHTP---PHVASALAGAVSPGALRRSLEAIKAMSSKGP 571 + G S+ PE V +P P A P +R + + SS Sbjct: 2557 GSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSS 2616 Query: 572 SASAALSPPLGSSPGSPGSQSLSSGETVPIPRPGPAQGDGHSLP 615 S+S++ S SS S S S SS + P PA+ +LP Sbjct: 2617 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALP 2660 Score = 40.0 bits (92), Expect = 0.008 Identities = 68/279 (24%), Positives = 99/279 (35%), Gaps = 31/279 (11%) Query: 367 SLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSGSREG 426 SL + P S + L + + P+ S+ AP N A R + + Sbjct: 2189 SLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAAN--------LASRIPAASAAAM 2240 Query: 427 SLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPS--------TPSAPEGYDLKI 478 +L+ AR P + S AA +L SP A++PS TP+AP + Sbjct: 2241 NLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPA-----V 2295 Query: 479 GLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTN--G 536 L+ A +L G+ + P+SS P VG H N G Sbjct: 2296 NLAGARTPAALAALSLTGSGTPPTAANY-PSSSRTPQAPASANLVGPRSAHATAPVNIAG 2354 Query: 537 VHTPPHVASA--LAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPL-----GSSPGSPG 589 T +A A + ++P +L + + S S SPPL +P S Sbjct: 2355 SRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAP 2414 Query: 590 SQSLSSGETVPIPRPGPAQGDGHSLPPIARRLGHHPPQS 628 SQS + E P P Q SL P A+ P S Sbjct: 2415 SQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPS 2453 Score = 40.0 bits (92), Expect = 0.008 Identities = 64/263 (24%), Positives = 98/263 (37%), Gaps = 31/263 (11%) Query: 357 APSGRAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQ 416 +PS R +PS + P P P + VP + QS P + + A Sbjct: 2426 SPSSRMGQAPSQSLLP-PAQDQPRSPVPSA--FSDQSRCLIAQTTPVAGSQSLSSGAVAT 2482 Query: 417 RQTPSGSREGSLS-PARGD-----GSPILNGGSLSPGTAAV------GGSSLDSPVQAIS 464 + +G G LS PA G G P + G+ P A SS S + S Sbjct: 2483 TTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSS 2542 Query: 465 PSTPSAPEGYDLKIGLSLAPRRGS-LPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTV 523 S+ S+ G S + GS LP Q ++ L + P+ + P + + Sbjct: 2543 SSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRV-------PSPTPAPKEAVREG-- 2593 Query: 524 GGSMRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGS 583 PPE T +S+ + + S + S + + SS S+S++ S S Sbjct: 2594 -----RPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2648 Query: 584 -SPGSPGSQSLSSGETVPIPRPG 605 SP PG Q+L + P PG Sbjct: 2649 PSPAKPGPQALPKPASPKKPPPG 2671 Score = 38.5 bits (88), Expect = 0.022 Identities = 77/311 (24%), Positives = 109/311 (35%), Gaps = 62/311 (19%) Query: 363 PLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCV------NGRWGTLRPRAQ 416 P +PS S P AL P+T RS+SP C+ +G ++ + Sbjct: 1470 PRTPSRGRSECDSSPEPKAL-PQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTV 1528 Query: 417 RQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDL 476 +TP G R S S D P S SP + SS DS + +P + G Sbjct: 1529 ARTPLGQRSRSGSSQELDVKP-----SASPQERSESDSSPDSKAKTRTPLRQRSRSGSSP 1583 Query: 477 KIGLS--LAPRR---GSLPDQKDL-----------------------------RLGSIDL 502 ++ L+PRR GS P+ KD R GS Sbjct: 1584 EVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSK 1643 Query: 503 NWDLKPASSSN----PMDGMDNRTVGGSMRHPPEQTNGVHTPPHVASALAGAVSPGALRR 558 P SS+ P +RT R PE TPP S+ + SP R+ Sbjct: 1644 GRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRS---SPELTRK 1700 Query: 559 SLEAIKAMSSKGPSASAALSPPLG------SSPGSPGSQSLSS--GETVPIPRPGPAQGD 610 + + ++ S+ + + +PP SSP P +S SS + PR Sbjct: 1701 ARLSRRSRSASSSPETRSRTPPRHRRSPSVSSP-EPAEKSRSSRRRRSASSPRTKTTSRR 1759 Query: 611 GHSLPPIARRL 621 G S P R L Sbjct: 1760 GRSPSPKPRGL 1770 Score = 33.5 bits (75), Expect = 0.70 Identities = 61/261 (23%), Positives = 91/261 (34%), Gaps = 63/261 (24%) Query: 355 SQAPSGRAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSM-DEAPCVNGRWGTLRP 413 S P ++ P S SP A ++ P+ R SP + P + G+ P Sbjct: 839 SPHPKVKSGTPPRQGSITSP-QANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPP 897 Query: 414 RAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEG 473 R + TP SP+R +SP + GSS SP + S +TP Sbjct: 898 RVKSSTPPRQ-----SPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTP----- 947 Query: 474 YDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTV---GGSMRHP 530 + + S +P +++R + S Sbjct: 948 ---------------------------------RRSRSVSPCSNVESRLLPRYSHSGSSS 974 Query: 531 PEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSP-PLGSSPGS-- 587 P+ TPP + +G++SP +KA + GPS S + SP P S S Sbjct: 975 PDTKVKPETPPR--QSHSGSISP------YPKVKAQTPPGPSLSGSKSPCPQEKSKDSLV 1026 Query: 588 ---PGSQSLSSGETVPIPRPG 605 PGS SL +G P PG Sbjct: 1027 QSCPGSLSLCAGVKSSTP-PG 1046 >gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] Length = 1336 Score = 43.9 bits (102), Expect = 5e-04 Identities = 44/198 (22%), Positives = 71/198 (35%), Gaps = 37/198 (18%) Query: 418 QTPSGSR--EGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYD 475 Q P G++ +G P G P +G PG+ + G P+ ++P P G Sbjct: 732 QGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPG-- 789 Query: 476 LKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTN 535 PR P + + +G P + GG + H P++ Sbjct: 790 --------PRENQGPAPQGMIMGH-------------PPQEMRGPHPPGGLLGHGPQEMR 828 Query: 536 GVHTPPHVASALAGAVSPGALRRSLEAIK----AMSSKGPSASAALSPPLGSSPGSPGSQ 591 G P + G G++ + ++ + S +GP + PP G G PG Q Sbjct: 829 G----PQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQ 884 Query: 592 SLSSGETVPIPRPGPAQG 609 G+ P P P+QG Sbjct: 885 ----GQQNPARGPHPSQG 898 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 43.1 bits (100), Expect = 9e-04 Identities = 63/288 (21%), Positives = 99/288 (34%), Gaps = 43/288 (14%) Query: 355 SQAPSGRAPLS-------PSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGR 407 S+ P+ R P S P+ N+ P P+S+ A Q +R E G+ Sbjct: 87 SRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGK 146 Query: 408 WGTLRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPST 467 T P+ + +G+R + P G SP + S + GT L P + P Sbjct: 147 -ATEAPKRSALS-AGARRDTSGPTPGTPSPAMARRSRAAGTEV----GLPRPAPSARPRP 200 Query: 468 PSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSM 527 P+ EG PR K + S + PA+ P + GG + Sbjct: 201 PT--EG----------PR-------KSVSSASEHSTTEPSPAARRRP-------SAGGGL 234 Query: 528 RHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGS 587 + P ++ P + A +G + G R S P AL PP + P Sbjct: 235 QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP----SQPKPKGLQALRPPQVTPPRK 290 Query: 588 PGSQSLSSGETVPIPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKPL 635 + +L + P+ P P+ PP H + + PL Sbjct: 291 DAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPL 338 Score = 39.7 bits (91), Expect = 0.010 Identities = 60/281 (21%), Positives = 87/281 (30%), Gaps = 13/281 (4%) Query: 355 SQAPSGRAPLSPSLNSRPSPISATPPALVPET-REYRSQSPVRSMDEAPCVNGRWGTLRP 413 ++ P+ RAP L RP PP + P R + V A G G P Sbjct: 14 ARTPAARAP--GLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71 Query: 414 RAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEG 473 + + G+ S P G +P + SP +A + P Sbjct: 72 ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQ 131 Query: 474 YDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQ 533 L+I RG + S D + P M R+ Sbjct: 132 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE----- 186 Query: 534 TNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSL 593 V P SA + G R+S+ + S+ PS +A P G P S+SL Sbjct: 187 ---VGLPRPAPSARPRPPTEGP-RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242 Query: 594 SSGETVPIPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKP 634 SS T P+ P + P P+ L +P Sbjct: 243 SSSAT-PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP 282 Score = 36.6 bits (83), Expect = 0.083 Identities = 65/250 (26%), Positives = 93/250 (37%), Gaps = 46/250 (18%) Query: 363 PLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSG 422 P S SL+S +P+S SP RS A GT R A P Sbjct: 237 PASRSLSSSATPLS----------------SPARSGPSAR------GTPRAPAHPSQPKP 274 Query: 423 S-----REGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTP-SAPEGYDL 476 R ++P R D +P L S SP ++L S P+TP S+ L Sbjct: 275 KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQL 334 Query: 477 KIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNG 536 L LAP S P L ++ P+ ++ + + + PP + Sbjct: 335 ATPLPLAPPSPSAPPS----LQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP--LSP 388 Query: 537 VHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSG 596 + TPP A P AL +L ++A S P AS LSP SP +P + ++ Sbjct: 389 LATPPPQA--------PPAL--ALPPLQAPPS--PPASPPLSPLATPSPQAPNALAVHLL 436 Query: 597 ETVPIPRPGP 606 + P P P Sbjct: 437 QAPFSPPPSP 446 Score = 32.3 bits (72), Expect = 1.6 Identities = 36/161 (22%), Positives = 58/161 (36%), Gaps = 6/161 (3%) Query: 311 DAWLLHMHSGPWAWQPLK--VENEEHGAPELW---CHPACRVGQCVVVFSQAPSGRAPLS 365 DA L H W+ P GAP W P G C + ++ P P Sbjct: 660 DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAP 719 Query: 366 PSLNSRPSPISATPPALVPETREYRSQSPVRS-MDEAPCVNGRWGTLRPRAQRQTPSGSR 424 +L+ PSP ++ A S+SP ++ + E P + ++ R + Sbjct: 720 GALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAA 779 Query: 425 EGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISP 465 EG+ + G GG AA+ + L + +SP Sbjct: 780 EGAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSP 820 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 43.1 bits (100), Expect = 9e-04 Identities = 64/283 (22%), Positives = 101/283 (35%), Gaps = 43/283 (15%) Query: 361 RAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTP 420 RAP P+ N+ P P+S+ A Q +R E G+ T P+ + Sbjct: 93 RAP--PAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGK-ATEAPKRSALS- 148 Query: 421 SGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGL 480 +G+R + P G SP + S + GT L P + P P+ EG Sbjct: 149 AGARRDTSGPTPGTPSPAMARRSRAAGTEV----GLPRPAPSARPRPPT--EG------- 195 Query: 481 SLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTP 540 PR K + S + PA+ P + GG ++ P ++ Sbjct: 196 ---PR-------KSVSSASEHSTTEPSPAARRRP-------SAGGGLQRPASRSLSSSAT 238 Query: 541 PHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVP 600 P + A +G + G R S P AL PP + P + +L + P Sbjct: 239 PLSSPARSGPSARGTPRAPAHP----SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 294 Query: 601 IPRPGPAQGDGHSLPPIARRLGHHP-----PQSLNVGKPLYQS 638 + P P+ S PP + L P + ++G P Q+ Sbjct: 295 LATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQA 337 Score = 34.3 bits (77), Expect = 0.41 Identities = 74/312 (23%), Positives = 107/312 (34%), Gaps = 63/312 (20%) Query: 366 PSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQR----QTPS 421 P+ ++RP P + P V E+ + P + P G G RP ++ TP Sbjct: 183 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG--GLQRPASRSLSSSATPL 240 Query: 422 GSREGSLSPARGD-------------GSPILNGGSLSP---GTAAVGGSSLDSPVQAISP 465 S S ARG G L ++P A G SP+ SP Sbjct: 241 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 300 Query: 466 STPSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGS--IDLNWDLKPASSSNPMDGMDNRTV 523 S P +P L P + P Q LGS + P+ +P+ Sbjct: 301 SAPPSPSAPPSLQTLPSPP--ATPPSQATTSLGSPTLQATHSFLPSPPLSPL-ATPPPQA 357 Query: 524 GGSMRHPPEQT--NGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPS--------- 572 ++ PP Q + +PP A +P AL ++ ++A S PS Sbjct: 358 PPALALPPLQAPPSPPASPPLSPLATPSPQAPNAL--AVHLLQAPFSPPPSPPVQAPFSP 415 Query: 573 -ASAALS---------------PPLGSSPGSPGSQSLSSGETVPIPRPGPAQGDGHSLPP 616 AS +S PPL P P S +S T P P P + PP Sbjct: 416 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL-----AAPP 470 Query: 617 IARRLGHHPPQS 628 + +L PPQ+ Sbjct: 471 L--QLAKPPPQA 480 Score = 32.7 bits (73), Expect = 1.2 Identities = 62/274 (22%), Positives = 98/274 (35%), Gaps = 27/274 (9%) Query: 355 SQAPSGRAPLSPSLNSRPSPISATP-PALVPETR----EYRSQSPVRSMDEAPCVNGRWG 409 ++AP A + + P TP PA+ +R E P S P G Sbjct: 139 TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRK 198 Query: 410 TLRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPS 469 ++ ++ T S P+ G G SLS + + P +P P+ Sbjct: 199 SVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPA 258 Query: 470 APEGYDLKIGLSLAPRRGSLPDQKDLR--LGSIDLNWDLKPASSSNPMDGMDN--RTVGG 525 P K +L P + + P +KD LG + + P+ S+ P +T+ Sbjct: 259 HPSQPKPKGLQALRPPQVT-PPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPS 317 Query: 526 SMRHPPEQTNG-------------VHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPS 572 PP Q + +PP A +P AL +L ++A S P Sbjct: 318 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL--ALPPLQAPPS--PP 373 Query: 573 ASAALSPPLGSSPGSPGSQSLSSGETVPIPRPGP 606 AS LSP SP +P + ++ + P P P Sbjct: 374 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 407 Score = 32.3 bits (72), Expect = 1.6 Identities = 36/161 (22%), Positives = 58/161 (36%), Gaps = 6/161 (3%) Query: 311 DAWLLHMHSGPWAWQPLK--VENEEHGAPELW---CHPACRVGQCVVVFSQAPSGRAPLS 365 DA L H W+ P GAP W P G C + ++ P P Sbjct: 621 DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAP 680 Query: 366 PSLNSRPSPISATPPALVPETREYRSQSPVRS-MDEAPCVNGRWGTLRPRAQRQTPSGSR 424 +L+ PSP ++ A S+SP ++ + E P + ++ R + Sbjct: 681 GALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAA 740 Query: 425 EGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISP 465 EG+ + G GG AA+ + L + +SP Sbjct: 741 EGAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSP 781 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 42.7 bits (99), Expect = 0.001 Identities = 72/291 (24%), Positives = 97/291 (33%), Gaps = 37/291 (12%) Query: 358 PSGRAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQR 417 PS AP PSL + PSP ATPP+ P + S+ P + P Q Sbjct: 346 PSPSAP--PSLQTLPSP-PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQA 402 Query: 418 QTPSGSREGSLSPARGDGSPILNGG----SLSPGTAAVGGSSLDSPVQAISPSTP----- 468 PS SL GSP L ++SP +S P S P Sbjct: 403 P-PSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPL 461 Query: 469 SAPEGYDLKIGLSLAPRRGSLP-------------------DQKDLRLGSIDLNWDLKPA 509 S P L+ LS A S P L + ++ L P Sbjct: 462 SLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPP 521 Query: 510 SSSNPMDGMDNRTVGG--SMRHPPEQTNGVH-TPPHVASALAGAVSPGALRRSLEAIKAM 566 S P + + S+ PP QT T PH+ + A P L+ + Sbjct: 522 SLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP--LQAPPSPLTTP 579 Query: 567 SSKGPSASAALSPPLGSSPGSPGSQSLSSGETVPIPRPGPAQGDGHSLPPI 617 + PS+ A P + SP Q L S P+ P P +LPP+ Sbjct: 580 PPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPL 630 Score = 42.4 bits (98), Expect = 0.002 Identities = 60/269 (22%), Positives = 95/269 (35%), Gaps = 43/269 (15%) Query: 355 SQAPSGRAPLS-------PSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGR 407 S+ P+ R P S P+ N+ P P+S+ A Q +R E G+ Sbjct: 87 SRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGK 146 Query: 408 WGTLRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPST 467 T P+ + +G+R + P G SP + S + GT L P + P Sbjct: 147 -ATEAPKRSALS-AGARRDTSGPTPGTPSPAMARRSRAAGTEV----GLPRPAPSARPRP 200 Query: 468 PSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSM 527 P+ EG PR K + S + PA+ P + GG + Sbjct: 201 PT--EG----------PR-------KSVSSASEHSTTEPSPAARRRP-------SAGGGL 234 Query: 528 RHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGS 587 + P ++ P + A +G + G R S P AL PP + P Sbjct: 235 QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP----SQPKPKGLQALRPPQVTPPRK 290 Query: 588 PGSQSLSSGETVPIPRPGPAQGDGHSLPP 616 + +L + P+ P P+ +PP Sbjct: 291 DAAPALGPLSSSPLATPSPSGTKARPVPP 319 Score = 39.7 bits (91), Expect = 0.010 Identities = 60/281 (21%), Positives = 87/281 (30%), Gaps = 13/281 (4%) Query: 355 SQAPSGRAPLSPSLNSRPSPISATPPALVPET-REYRSQSPVRSMDEAPCVNGRWGTLRP 413 ++ P+ RAP L RP PP + P R + V A G G P Sbjct: 14 ARTPAARAP--GLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71 Query: 414 RAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEG 473 + + G+ S P G +P + SP +A + P Sbjct: 72 ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQ 131 Query: 474 YDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQ 533 L+I RG + S D + P M R+ Sbjct: 132 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE----- 186 Query: 534 TNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSL 593 V P SA + G R+S+ + S+ PS +A P G P S+SL Sbjct: 187 ---VGLPRPAPSARPRPPTEGP-RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242 Query: 594 SSGETVPIPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKP 634 SS T P+ P + P P+ L +P Sbjct: 243 SSSAT-PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP 282 Score = 35.0 bits (79), Expect = 0.24 Identities = 73/317 (23%), Positives = 115/317 (36%), Gaps = 31/317 (9%) Query: 321 PWAWQPLKVENEEHGAPELWCHPACRVGQCVVVFSQAPSGRAPLSPSLNSRPSPISATPP 380 P A PL+V +P + P+ V AP + P SP + SP++ PP Sbjct: 729 PLAAPPLQVPPSPPASPPM--SPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPP 786 Query: 381 ALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSGSREGS-LSPARGDGSPIL 439 P + P++++ P P +PS S S L+ P+L Sbjct: 787 QAPPAL----ATPPLQALPSPP-------ASFPGQAPFSPSASLPMSPLATPPPQAPPVL 835 Query: 440 NGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGLSLAPRRGSLPDQK-DLRLG 498 L + +L +P + +P ++ G ++ L+LAP P + L Sbjct: 836 AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG--PRLTLALAPGPPPPPSRSPSSTLS 893 Query: 499 SIDLNWDLKPASSS-NPMDGMDNRTVGGSMRHPPEQTNGVHTPPHVASALAGAVSPGALR 557 DL A+S+ + G D+ GG+ PP H A+ G P A R Sbjct: 894 GPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAE--LAACHPAAWSRGPAPPLAFR 951 Query: 558 RSLEA-IKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVPIPRPGPAQG------- 609 + A + + GP ++ L + P S + + G P P PG + G Sbjct: 952 GAPGAPLPWPPATGPGSADGLCTIYETE--GPESATPAPGALDPGPSPGTSGGKAAAGAG 1009 Query: 610 -DGHSLPPIARRLGHHP 625 S P RLG P Sbjct: 1010 AGASSRSPKQARLGELP 1026 Score = 32.3 bits (72), Expect = 1.6 Identities = 61/297 (20%), Positives = 97/297 (32%), Gaps = 60/297 (20%) Query: 357 APSGRAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQ 416 +P + LSP+++ SP++ P + + Q+P+ S+ + P + Sbjct: 466 SPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSL------------IMPPLE 513 Query: 417 RQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDL 476 Q+ PA P+ N SL+P + L +P TP P L Sbjct: 514 TQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTP----HLETPPCPAPCPL 569 Query: 477 KIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNG 536 + AP + PA +S P+ G+ + + PP+ Sbjct: 570 Q-----APPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPX 624 Query: 537 VHTPPHVAS------------ALAGAVSPGALRRSLEAIKAMSSKGPS----------AS 574 + PP A A +P AL ++ ++A S PS AS Sbjct: 625 LALPPLQAPPSPPASPPLSPLATPSPQAPNAL--AVHLLQAPFSPPPSPPVQAPFSPPAS 682 Query: 575 AALS---------------PPLGSSPGSPGSQSLSSGETVPIPRPGPAQGDGHSLPP 616 +S PPL P P S +S T P P P +PP Sbjct: 683 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPP 739 Score = 32.3 bits (72), Expect = 1.6 Identities = 36/161 (22%), Positives = 58/161 (36%), Gaps = 6/161 (3%) Query: 311 DAWLLHMHSGPWAWQPLK--VENEEHGAPELW---CHPACRVGQCVVVFSQAPSGRAPLS 365 DA L H W+ P GAP W P G C + ++ P P Sbjct: 929 DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAP 988 Query: 366 PSLNSRPSPISATPPALVPETREYRSQSPVRS-MDEAPCVNGRWGTLRPRAQRQTPSGSR 424 +L+ PSP ++ A S+SP ++ + E P + ++ R + Sbjct: 989 GALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAA 1048 Query: 425 EGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISP 465 EG+ + G GG AA+ + L + +SP Sbjct: 1049 EGAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSP 1089 >gi|72004269 tetra-peptide repeat homeobox [Homo sapiens] Length = 411 Score = 42.7 bits (99), Expect = 0.001 Identities = 64/272 (23%), Positives = 96/272 (35%), Gaps = 49/272 (18%) Query: 361 RAPLSPSLNSRPSPI----SATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQ 416 R P +R +P+ SA+ P P ++ + S+ +A WG RAQ Sbjct: 32 RVPGQRGRGARAAPLVPAASASAPQRGPSGILPAAEPTICSLHQA------WGGPGCRAQ 85 Query: 417 RQTPSGSREGSLSPARGDGSPILNGGSLSPGTAA-------VGGSSLDSPVQAISPSTPS 469 + P+ +LSP G + G + PG G + + SP+ A P S Sbjct: 86 KGIPA-----ALSPGPGPIPAPIPGPAQIPGPLPGSIPGPIPGPAQIPSPIPAPIPGPIS 140 Query: 470 APEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRH 529 P P RG +P P S P+ G + G Sbjct: 141 GPVQIP-------GPFRGPIPG----------------PISGPAPIPGPISGPFSGPNPG 177 Query: 530 PPEQTNGVHTPPHVASALAGAVS---PGALRRSLEAIKAMSSKGPSASAALSPPLGSSPG 586 P N P ++ + G +S PG + + + + GP P G +PG Sbjct: 178 PIPGPNPGPIPGPISGPIPGPISVPIPGPIPGPISGPISGPNPGPIPGPIPGPISGPNPG 237 Query: 587 S-PGSQSLSSGETVPIPRPGPAQGDGHSLPPI 617 PG S + +P P PGP G G + PI Sbjct: 238 PIPGPISGPNPGLIPGPIPGPISGPGPIIGPI 269 >gi|59806361 hypothetical protein LOC387104 [Homo sapiens] Length = 947 Score = 41.6 bits (96), Expect = 0.003 Identities = 70/279 (25%), Positives = 99/279 (35%), Gaps = 52/279 (18%) Query: 355 SQAPSGRAPLSPSLNSRPSPISATPPALVPE---TREYRSQSPVRSMDEA---------- 401 SQ P G A +P+ + +AT L PE ++ R+QSP R D + Sbjct: 2 SQPPIGGA--APATAAASPAAAATEARLHPEGSSRKQQRAQSPARPRDSSLRQTIAATRS 59 Query: 402 PCVNG------RWGTLRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSS 455 P G R L+ + Q+ +GSR G + RG G L+P AA G Sbjct: 60 PVGAGTKLNSVRQQQLQQQQQQGNKTGSRTGPPASIRGGGGGAEKATPLAPKGAAPGAVQ 119 Query: 456 LDSPVQAISPSTPSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPM 515 + +A +T +A L RR P++ L S+ P Sbjct: 120 PVAGAEAAPAATLAA-----------LGGRRPGPPEEPPRELESVPSKLGEPPPLGEGGG 168 Query: 516 DGMDNRTVGGSMRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASA 575 G + GG E+ G PP P R + ++A G Sbjct: 169 GGGEGGGAGGG---SGEREGGAPQPP----------PPRGWRG--KGVRAQQRGGSGGEG 213 Query: 576 ALSPPLGSSPG-SPGSQSLSSGETVPIPRPGPAQGDGHS 613 A P SS G +PG+ S +SG V G G G S Sbjct: 214 ASPSPSSSSAGKTPGTGSRNSGSGV----AGGGSGGGGS 248 >gi|54860079 nadrin isoform 1 [Homo sapiens] Length = 881 Score = 41.6 bits (96), Expect = 0.003 Identities = 70/296 (23%), Positives = 106/296 (35%), Gaps = 49/296 (16%) Query: 357 APSGRAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQ 416 +P+ + PL P+ S P PP P++ S S GT+ Sbjct: 520 SPAFQPPLPPTDGSTVVPAGPEPP---PQSSRAESSSG-------------GGTV----- 558 Query: 417 RQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEG-YD 475 PS + P+ GDGSP P +AAV ++ A + P A G + Sbjct: 559 ---PSSAGILEQGPSPGDGSP---PKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQ 612 Query: 476 LKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPE--- 532 L +G P + P LR ++ P + P ++ G+ +HPP Sbjct: 613 LSMG---QPHNAAGPSPHTLRR-AVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSP 668 Query: 533 ---------QTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGS 583 T PP SA + +P SL I+A + P +P + + Sbjct: 669 KPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHT 728 Query: 584 SP---GSPGSQSLSSGETVPIPRPGPAQ-GDGHSLPPIARRLGHHP-PQSLNVGKP 634 P G P +L S + P P Q S PP+ ++ P PQ+L G P Sbjct: 729 KPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNP 784 Score = 41.6 bits (96), Expect = 0.003 Identities = 59/226 (26%), Positives = 86/226 (38%), Gaps = 45/226 (19%) Query: 410 TLRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPS 469 TLR ++ P+ + G+ P G P GG S GT+ S P SPS P+ Sbjct: 628 TLRRAVKKPAPAPPKPGNPPP----GHP---GGQSSSGTSQHPPSLSPKPPTR-SPSPPT 679 Query: 470 APEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRH 529 G P + S P Q L+ + +SS +P+ + H Sbjct: 680 QHTGQP--------PGQPSAPSQ---------LSAPRRYSSSLSPIQAPN---------H 713 Query: 530 PPEQTNGVHTP-PHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGS-SPGS 587 PP Q TP H G +P AL + + + + +PPLG +P Sbjct: 714 PPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSL 773 Query: 588 PGSQSLSSGE---------TVPIPRPGPAQGDGHSLPPIARRLGHH 624 P Q+L+ G T+P PRP P + S+PP + G H Sbjct: 774 PAPQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQPPGVH 819 >gi|54860105 nadrin isoform 2 [Homo sapiens] Length = 803 Score = 41.6 bits (96), Expect = 0.003 Identities = 59/226 (26%), Positives = 86/226 (38%), Gaps = 45/226 (19%) Query: 410 TLRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPS 469 TLR ++ P+ + G+ P G P GG S GT+ S P SPS P+ Sbjct: 550 TLRRAVKKPAPAPPKPGNPPP----GHP---GGQSSSGTSQHPPSLSPKPPTR-SPSPPT 601 Query: 470 APEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRH 529 G P + S P Q L+ + +SS +P+ + H Sbjct: 602 QHTGQP--------PGQPSAPSQ---------LSAPRRYSSSLSPIQAPN---------H 635 Query: 530 PPEQTNGVHTP-PHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGS-SPGS 587 PP Q TP H G +P AL + + + + +PPLG +P Sbjct: 636 PPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSL 695 Query: 588 PGSQSLSSGE---------TVPIPRPGPAQGDGHSLPPIARRLGHH 624 P Q+L+ G T+P PRP P + S+PP + G H Sbjct: 696 PAPQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQPPGVH 741 Score = 35.0 bits (79), Expect = 0.24 Identities = 55/243 (22%), Positives = 87/243 (35%), Gaps = 31/243 (12%) Query: 419 TPSGSREGSLSPARGDGSPILNGGSLS---------PGTAAVGGSSLDSPVQAISPSTPS 469 T + S G+L R ++ G + P +AAV ++ A + P Sbjct: 468 TGNDSDSGTLERKRPASMAVMEGDLVKKESPPKPKDPVSAAVPAPGRNNSQIASGQNQPQ 527 Query: 470 APEG-YDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMR 528 A G + L +G P + P LR ++ P + P ++ G+ + Sbjct: 528 AAAGSHQLSMG---QPHNAAGPSPHTLRR-AVKKPAPAPPKPGNPPPGHPGGQSSSGTSQ 583 Query: 529 HPPE------------QTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAA 576 HPP T PP SA + +P SL I+A + P Sbjct: 584 HPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQ 643 Query: 577 LSPPLGSSP---GSPGSQSLSSGETVPIPRPGPAQ-GDGHSLPPIARRLGHHP-PQSLNV 631 +P + + P G P +L S + P P Q S PP+ ++ P PQ+L Sbjct: 644 ATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAG 703 Query: 632 GKP 634 G P Sbjct: 704 GNP 706 >gi|72256200 B-cell CLL/lymphoma 9 [Homo sapiens] Length = 1426 Score = 41.6 bits (96), Expect = 0.003 Identities = 58/253 (22%), Positives = 98/253 (38%), Gaps = 14/253 (5%) Query: 363 PLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQ---T 419 PL+PS N P+ ++ PP R+ S S +P +N + Q + Sbjct: 821 PLNPSSN--PTSLNTAPPVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGS 878 Query: 420 PSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIG 479 PSG+ + +P++ G + S + V GS+ SPV SPS P+ G+ Sbjct: 879 PSGNLKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTSSPK 938 Query: 480 LSLAP------RRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRH--PP 531 L + L LG+++ + P ++S P ++ S + PP Sbjct: 939 PPLQSPGIPPNHKAPLTMASPAMLGNVE-SGGPPPPTASQPASVNIPGSLPSSTPYTMPP 997 Query: 532 EQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQ 591 E T + + S ++ P + +AIK ++S + A SP L S PG Sbjct: 998 EPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMG 1057 Query: 592 SLSSGETVPIPRP 604 + + P P Sbjct: 1058 INTQNPRISGPNP 1070 Score = 33.1 bits (74), Expect = 0.92 Identities = 38/131 (29%), Positives = 47/131 (35%), Gaps = 22/131 (16%) Query: 505 DLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAI- 563 D KP P ++ + R P TPP A A A P L R + Sbjct: 230 DPKPLPQQPPAPANQDQNSSQNTRLQP-------TPPIPAPAPKPAAPPRPLDRESPGVE 282 Query: 564 -KAMSSKGPSASAALSPPLGSSPGS--------PGSQSLSSGETVPIPRPGPAQGDGHSL 614 K + S G AS+ PP G+ P S P SQ +S P P P G Sbjct: 283 NKLIPSVGSPASSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGE-- 340 Query: 615 PPIARRLGHHP 625 PP LG +P Sbjct: 341 PP---TLGENP 348 Score = 31.6 bits (70), Expect = 2.7 Identities = 90/361 (24%), Positives = 132/361 (36%), Gaps = 63/361 (17%) Query: 363 PLSPSLNSRPSPISA---TPPALVPETREYRSQSPV--RSMDEAPCV-NGRWGTLRPRAQ 416 PLS S N PSP + PP VP S +P+ E P V GR G + Sbjct: 1085 PLSHS-NQMPSPNAVGPNIPPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPP 1143 Query: 417 RQTPSGSREGSLS-PARGDGSPILNGGSLSPGTAAVGGSS----LDSPVQAISPSTPSAP 471 Q+P + P+ G GS GG PG +G S + P P P Sbjct: 1144 VQSPPQQVPFPHNGPSGGQGS--FPGGMGFPGEGPLGRPSNLPQSSADAALCKPGGPGGP 1201 Query: 472 EGYDLKIGLSLAPRRGSLPD-QKDLRLGS-----IDLNWDLKPASSSNPMDGMDNRTVGG 525 + + + +G S+ P + PD Q+ +R G+ DL+ + S + V G Sbjct: 1202 DSFTV-LGNSM-PSVFTDPDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPG 1259 Query: 526 SMRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSP 585 +Q G P S + G + A R L A+ M GP + + PLG++P Sbjct: 1260 R-----KQPQG---PGPGFSHMQGMMGEQAPRMGL-ALPGMGGPGPVGTPDI--PLGTAP 1308 Query: 586 GSPGSQSLSSGETVPIPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKPLYQSMNCKPMQ 645 PG P PA + P R + P QS G+P S + Sbjct: 1309 SMPGHN----------PMRPPAFLQQGMMGPHHRMMS--PAQSTMPGQPTLMSNPAAAVG 1356 Query: 646 MYVLDIKDTKEKGRVKWKVFNSSSVVGPPETSLHTVVQGRGELIIFGGLMDKKQNVKYYP 705 M + KD G ++ VG P G ++ G+M +QN+ P Sbjct: 1357 M--IPGKDRGPAG-----LYTHPGPVGSP-----------GMMMSMQGMMGPQQNIMIPP 1398 Query: 706 K 706 + Sbjct: 1399 Q 1399 >gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] Length = 904 Score = 41.6 bits (96), Expect = 0.003 Identities = 77/280 (27%), Positives = 97/280 (34%), Gaps = 43/280 (15%) Query: 365 SPSLNSRPSPISATPPALVPETREYRSQSPV-----RSMDEAPCVNGRWGTLRPRAQRQT 419 SPS ++ PSP P R RS SP RS AP R T P +R+T Sbjct: 524 SPSRSASPSPRKRQKETS-PRGRRRRSPSPPPTRRRRSPSPAPPPRRR-RTPTPPPRRRT 581 Query: 420 PSGS-REGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTP---------- 468 PS R S SP R PI S SP S P + SPS P Sbjct: 582 PSPPPRRRSPSPRRYS-PPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPP 640 Query: 469 ----SAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPA-------SSSNPMDG 517 S+P LS R+GS P + S N P+ +SS+P Sbjct: 641 PKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPV 700 Query: 518 MDNRTVGGSMRHPPEQTNGV-----HTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPS 572 + R P + TP A + SP ++RR + S G Sbjct: 701 RRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR---VSSSRSVSGSP 757 Query: 573 ASAALSPPLGSSPGSPGSQSLSSGETVPI-----PRPGPA 607 AA PP SP S S + VP+ P P P+ Sbjct: 758 EPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPS 797 Score = 39.7 bits (91), Expect = 0.010 Identities = 65/270 (24%), Positives = 89/270 (32%), Gaps = 63/270 (23%) Query: 366 PSLNSRPSPISATPP-ALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSGSR 424 PS RPSP TPP + P R RS+SPVR + +L + + S SR Sbjct: 315 PSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSS------ASLSGSSSSSSSSRSR 368 Query: 425 EGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGLSLAP 484 P + SP LSP S P + PS P+ P Sbjct: 369 SPPKKPPKRTSSPPRKTRRLSP--------SASPPRRRHRPSPPATP------------- 407 Query: 485 RRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTPPHVA 544 P + +P NRT + P +T+G T H Sbjct: 408 ----------------------PPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVT-KHKG 444 Query: 545 SALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPP------LGSSPGSPGSQSLSSGET 598 + + SP R +E ++ KG +AA S + S S S SS E Sbjct: 445 TEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSED 504 Query: 599 VPIPRPGPAQGDGHSLPPIARRLGHHPPQS 628 R G+ + RR H P +S Sbjct: 505 ERPKRSHVKNGE------VGRRRRHSPSRS 528 Score = 32.7 bits (73), Expect = 1.2 Identities = 36/121 (29%), Positives = 47/121 (38%), Gaps = 7/121 (5%) Query: 355 SQAPSGRAPLSPSLNSR--PSPISATPP--ALVPETREYRSQSPVRSMDEAPCVNGRWGT 410 S + S R SP N R PSP P + P R S SP R +P Sbjct: 665 SPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRV 724 Query: 411 LRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSA 470 R ++ + S R S ++G SP AA + SPVQ+ SPST + Sbjct: 725 SRTPEPKKIKKAASPSPQSVRRVSSSRSVSG---SPEPAAKKPPAPPSPVQSQSPSTNWS 781 Query: 471 P 471 P Sbjct: 782 P 782 >gi|158508542 kelch-like 33 [Homo sapiens] Length = 453 Score = 41.2 bits (95), Expect = 0.003 Identities = 50/221 (22%), Positives = 82/221 (37%), Gaps = 33/221 (14%) Query: 86 AHQCYHGFMKAVQEGNIQWESRTYPYPGTPITQRFSHSACYYDANQSMYVFGGCTQSSCN 145 A +C G ++ V+ G + P P RF H A A +YV GG S + Sbjct: 157 AFRCGVGLVRTVEWGQL---------PALPAPGRFRHGAASL-AGSELYVCGGQDFYSHS 206 Query: 146 AAFNDLWRLDLNSKEW--IRPLASGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQP 203 R + + ++W + PL+ ++ +LV L GG Sbjct: 207 NTLASTLRWEPSQEDWEEMAPLSQA-----RSLFSLVALDGKLYALGG---------RHN 252 Query: 204 ERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVL 263 + D + TY+P N W P P H++ +++ ++ V GG G+ Q + Sbjct: 253 DVALDSVETYNPELNVWRPAPAL--PAPCFAHAAAILEGQLYVSGGCGGTGQYLASLMHY 310 Query: 264 DLEQWAWSKP-NISGPSPHPRGGQSQIVIDDATILILGGCG 303 D + KP P PR G + + + GG G Sbjct: 311 DPK---LEKPGTFLSPMGVPRAGHVMAAL-GGRLYVAGGLG 347 Score = 38.9 bits (89), Expect = 0.017 Identities = 30/108 (27%), Positives = 48/108 (44%), Gaps = 15/108 (13%) Query: 133 MYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLFGGW 192 +YV GG ++ +F + + L +S + PL PSP GA V + L++ GG+ Sbjct: 340 LYVAGGLGETEDLLSF-EAYELRTDSWTHLAPL-----PSPHVGAASAVLQGELLVLGGY 393 Query: 193 TRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVI 240 + H+ IH Y P W C+ T P P A +C++ Sbjct: 394 S-------HRTYALSHLIHAYCPGLGRWLCLGTL--PRPRAEMPACIL 432 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.132 0.416 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 35,832,405 Number of Sequences: 37866 Number of extensions: 2100080 Number of successful extensions: 9164 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 63 Number of HSP's successfully gapped in prelim test: 497 Number of HSP's that attempted gapping in prelim test: 7940 Number of HSP's gapped (non-prelim): 1560 length of query: 717 length of database: 18,247,518 effective HSP length: 110 effective length of query: 607 effective length of database: 14,082,258 effective search space: 8547930606 effective search space used: 8547930606 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.