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Search of human proteins with 62955044
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|62955044 F-box protein 42 [Homo sapiens]
(717 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62955044 F-box protein 42 [Homo sapiens] 1494 0.0
gi|26190616 kelch domain containing 1 [Homo sapiens] 77 6e-14
gi|98986457 host cell factor 1 [Homo sapiens] 75 3e-13
gi|7657301 kelch domain containing 2 [Homo sapiens] 72 2e-12
gi|7019405 host cell factor C2 [Homo sapiens] 70 7e-12
gi|16945972 kelch domain containing 3 [Homo sapiens] 67 4e-11
gi|21314675 kelch domain containing 4 [Homo sapiens] 65 2e-10
gi|47717139 leucine-zipper-like transcription regulator 1 [Homo ... 63 1e-09
gi|195963410 MEF2 activating motif and SAP domain containing tra... 58 3e-08
gi|145701025 multiple EGF-like-domains 8 [Homo sapiens] 56 1e-07
gi|33695109 Rab9 effector protein with kelch motifs [Homo sapiens] 55 2e-07
gi|44917619 kelch domain containing 10 [Homo sapiens] 54 4e-07
gi|20143482 melanoma antigen family E, 1 [Homo sapiens] 50 6e-06
gi|46410931 attractin-like 1 [Homo sapiens] 50 7e-06
gi|163965366 nascent polypeptide-associated complex alpha subuni... 50 9e-06
gi|21450863 attractin isoform 2 [Homo sapiens] 48 4e-05
gi|21450861 attractin isoform 1 [Homo sapiens] 48 4e-05
gi|146219832 myosin light chain kinase 3 [Homo sapiens] 45 2e-04
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 44 4e-04
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 44 5e-04
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 43 9e-04
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 43 9e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 43 0.001
gi|72004269 tetra-peptide repeat homeobox [Homo sapiens] 43 0.001
gi|59806361 hypothetical protein LOC387104 [Homo sapiens] 42 0.003
gi|54860079 nadrin isoform 1 [Homo sapiens] 42 0.003
gi|54860105 nadrin isoform 2 [Homo sapiens] 42 0.003
gi|72256200 B-cell CLL/lymphoma 9 [Homo sapiens] 42 0.003
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 42 0.003
gi|158508542 kelch-like 33 [Homo sapiens] 41 0.003
>gi|62955044 F-box protein 42 [Homo sapiens]
Length = 717
Score = 1494 bits (3868), Expect = 0.0
Identities = 717/717 (100%), Positives = 717/717 (100%)
Query: 1 MASSSDSEDDSFMAVDQEETVLEGTMDQDEEPHPVLEAEETRHNRSMSELPEEVLEYILS 60
MASSSDSEDDSFMAVDQEETVLEGTMDQDEEPHPVLEAEETRHNRSMSELPEEVLEYILS
Sbjct: 1 MASSSDSEDDSFMAVDQEETVLEGTMDQDEEPHPVLEAEETRHNRSMSELPEEVLEYILS 60
Query: 61 FLSPYQEHKTAALVCKQWYRLIKGVAHQCYHGFMKAVQEGNIQWESRTYPYPGTPITQRF 120
FLSPYQEHKTAALVCKQWYRLIKGVAHQCYHGFMKAVQEGNIQWESRTYPYPGTPITQRF
Sbjct: 61 FLSPYQEHKTAALVCKQWYRLIKGVAHQCYHGFMKAVQEGNIQWESRTYPYPGTPITQRF 120
Query: 121 SHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLV 180
SHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLV
Sbjct: 121 SHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLV 180
Query: 181 VYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVI 240
VYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVI
Sbjct: 181 VYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVI 240
Query: 241 DDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDATILILG 300
DDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDATILILG
Sbjct: 241 DDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDATILILG 300
Query: 301 GCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELWCHPACRVGQCVVVFSQAPSG 360
GCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELWCHPACRVGQCVVVFSQAPSG
Sbjct: 301 GCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELWCHPACRVGQCVVVFSQAPSG 360
Query: 361 RAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTP 420
RAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTP
Sbjct: 361 RAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTP 420
Query: 421 SGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGL 480
SGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGL
Sbjct: 421 SGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGL 480
Query: 481 SLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTP 540
SLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTP
Sbjct: 481 SLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTP 540
Query: 541 PHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVP 600
PHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVP
Sbjct: 541 PHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVP 600
Query: 601 IPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKPLYQSMNCKPMQMYVLDIKDTKEKGRV 660
IPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKPLYQSMNCKPMQMYVLDIKDTKEKGRV
Sbjct: 601 IPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKPLYQSMNCKPMQMYVLDIKDTKEKGRV 660
Query: 661 KWKVFNSSSVVGPPETSLHTVVQGRGELIIFGGLMDKKQNVKYYPKTNALYFVRAKR 717
KWKVFNSSSVVGPPETSLHTVVQGRGELIIFGGLMDKKQNVKYYPKTNALYFVRAKR
Sbjct: 661 KWKVFNSSSVVGPPETSLHTVVQGRGELIIFGGLMDKKQNVKYYPKTNALYFVRAKR 717
>gi|26190616 kelch domain containing 1 [Homo sapiens]
Length = 406
Score = 77.0 bits (188), Expect = 6e-14
Identities = 68/252 (26%), Positives = 117/252 (46%), Gaps = 33/252 (13%)
Query: 115 PITQRFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKE----WIRPLA-SGS 169
P + S AC N +Y+FGG + N L+ ++L +++ W + G
Sbjct: 66 PASMSGSCGACI---NGKLYIFGGYDDKGYS---NRLYFVNLRTRDETYIWEKITDFEGQ 119
Query: 170 YPSPKAGATLVVYKDLLVLFGGW--TRPSP----YPLHQP---ERFF----DEIHTY-SP 215
P+P+ + VYKD L+ FGG+ R S + +H E+ F +++H + +
Sbjct: 120 PPTPRDKLSCWVYKDRLIYFGGYGCRRHSELQDCFDVHDASWEEQIFWGWHNDVHIFDTK 179
Query: 216 SKNWWNCIVTTHGPP-PMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWS-KP 273
++ W+ + PP P A H+ V+ +K +FGG + +M ND+ L+L+ W WS +
Sbjct: 180 TQTWFQPEIKGGVPPQPRAAHTCAVLGNKGYIFGGRVLQTRM-NDLHYLNLDTWTWSGRI 238
Query: 274 NISGPSPHPRGGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVENEE 333
I+G SP R + I D + + GG N D W+ ++ + W ++ +
Sbjct: 239 TINGESPKHRSWHTLTPIADDKLFLCGGLSADNIPLSDGWIHNVTTNCWK----QLTHLP 294
Query: 334 HGAPELWCHPAC 345
P LW H AC
Sbjct: 295 KTRPRLW-HTAC 305
Score = 52.0 bits (123), Expect = 2e-06
Identities = 53/235 (22%), Positives = 84/235 (35%), Gaps = 36/235 (15%)
Query: 133 MYVFGGCTQSSCNAAF---NDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLF 189
+YV+GG N + +++W D++S W L G P+ +G+ L +F
Sbjct: 25 LYVWGGYVSIEDNEVYLPNDEIWTYDIDSGLWRMHLMEGELPASMSGSCGACINGKLYIF 84
Query: 190 GGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSC-VIDDKMIVFG 248
GG+ + +F + T + W PP SC V D++I FG
Sbjct: 85 GGYDDKG----YSNRLYFVNLRTRDETYIWEKITDFEGQPPTPRDKLSCWVYKDRLIYFG 140
Query: 249 GSLGSRQMS----------------------NDVWVLDLEQWAWSKPNI-SGPSPHPRGG 285
G G R+ S NDV + D + W +P I G P PR
Sbjct: 141 G-YGCRRHSELQDCFDVHDASWEEQIFWGWHNDVHIFDTKTQTWFQPEIKGGVPPQPRAA 199
Query: 286 QSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELW 340
+ V+ + + GG + L +++ W W N E W
Sbjct: 200 HTCAVLGNKGYIF----GGRVLQTRMNDLHYLNLDTWTWSGRITINGESPKHRSW 250
>gi|98986457 host cell factor 1 [Homo sapiens]
Length = 2035
Score = 74.7 bits (182), Expect = 3e-13
Identities = 66/253 (26%), Positives = 106/253 (41%), Gaps = 45/253 (17%)
Query: 133 MYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLA----SGSYPSPKAGATLVVYKDLLVL 188
+ VFGG + + NDL+ L + EW R A +G P P+ G + + + L
Sbjct: 94 LLVFGGMVEYGKYS--NDLYELQASRWEWKRLKAKTPKNGPPPCPRLGHSFSLVGNKCYL 151
Query: 189 FGGWTRPSPYPLHQPERFFDEIHTYS--PSKNW--WNCIVTTHG--PPPMAGHSSCVIDD 242
FGG S P + R+ ++++ P W+ I T+G PPP H++ V +
Sbjct: 152 FGGLANDSEDPKNNIPRYLNDLYILELRPGSGVVAWD-IPITYGVLPPPRESHTAVVYTE 210
Query: 243 K------MIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDATI 296
K ++++GG G R D+W LD++ W+KP++SG +P PR S I +
Sbjct: 211 KDNKKSKLVIYGGMSGCRL--GDLWTLDIDTLTWNKPSLSGVAPLPRSLHSATTIGNKMY 268
Query: 297 LILGGCGGPNALFKDAWLLHMHSGPW--------------AWQPLKVENEEHGAPELWCH 342
+ GG L D + H W AW+ + ++ E P
Sbjct: 269 VF----GGWVPLVMDDVKVATHEKEWKCTNTLACLNLDTMAWETILMDTLEDNIPR---- 320
Query: 343 PACRVGQCVVVFS 355
R G C V +
Sbjct: 321 --ARAGHCAVAIN 331
Score = 65.9 bits (159), Expect = 1e-10
Identities = 44/140 (31%), Positives = 65/140 (46%), Gaps = 17/140 (12%)
Query: 167 SGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTT 226
SG P P+ G V K+L+V+FGG E DE+H Y+ + N W I
Sbjct: 26 SGPVPRPRHGHRAVAIKELIVVFGGGN----------EGIVDELHVYNTATNQW-FIPAV 74
Query: 227 HG--PPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAW----SKPNISGPSP 280
G PP A + +++VFGG + + SND++ L +W W +K +GP P
Sbjct: 75 RGDIPPGCAAYGFVCDGTRLLVFGGMVEYGKYSNDLYELQASRWEWKRLKAKTPKNGPPP 134
Query: 281 HPRGGQSQIVIDDATILILG 300
PR G S ++ + L G
Sbjct: 135 CPRLGHSFSLVGNKCYLFGG 154
Score = 53.5 bits (127), Expect = 7e-07
Identities = 44/178 (24%), Positives = 74/178 (41%), Gaps = 43/178 (24%)
Query: 119 RFSHSACYY----DANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPK 174
R SH+A Y + + ++GG S C DLW LD+++ W +P SG P P+
Sbjct: 200 RESHTAVVYTEKDNKKSKLVIYGG--MSGCR--LGDLWTLDIDTLTWNKPSLSGVAPLPR 255
Query: 175 AGATLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNW--------------- 219
+ + + + +FGGW PL D++ + K W
Sbjct: 256 SLHSATTIGNKMYVFGGWV-----PL-----VMDDVKVATHEKEWKCTNTLACLNLDTMA 305
Query: 220 WNCI----VTTHGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSN------DVWVLDLEQ 267
W I + + P AGH + I+ ++ ++ G G R+ N D+W L+ E+
Sbjct: 306 WETILMDTLEDNIPRARAGHCAVAINTRLYIWSGRDGYRKAWNNQVCCKDLWYLETEK 363
Score = 48.9 bits (115), Expect = 2e-05
Identities = 49/210 (23%), Positives = 81/210 (38%), Gaps = 36/210 (17%)
Query: 135 VFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLFGGWTR 194
VFGG + ++L + + +W P G P A V L++FGG
Sbjct: 47 VFGGGNEG----IVDELHVYNTATNQWFIPAVRGDIPPGCAAYGFVCDGTRLLVFGGMVE 102
Query: 195 PSPYPLHQPERFFDEIHTYSPSKNWWNCI---VTTHGPP--PMAGHSSCVIDDKMIVFGG 249
Y ++++ S+ W + +GPP P GHS ++ +K +FGG
Sbjct: 103 YGKYS--------NDLYELQASRWEWKRLKAKTPKNGPPPCPRLGHSFSLVGNKCYLFGG 154
Query: 250 SLGSRQ--------MSNDVWVLDLEQW----AWSKPNISGPSPHPRGGQSQIVIDD---- 293
+ ND+++L+L AW P G P PR + +V +
Sbjct: 155 LANDSEDPKNNIPRYLNDLYILELRPGSGVVAWDIPITYGVLPPPRESHTAVVYTEKDNK 214
Query: 294 -ATILILGGCGGPNALFKDAWLLHMHSGPW 322
+ ++I GG G D W L + + W
Sbjct: 215 KSKLVIYGGMSG--CRLGDLWTLDIDTLTW 242
>gi|7657301 kelch domain containing 2 [Homo sapiens]
Length = 406
Score = 71.6 bits (174), Expect = 2e-12
Identities = 60/241 (24%), Positives = 93/241 (38%), Gaps = 28/241 (11%)
Query: 124 ACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKE----WIRPLASGSYPSPKAGATL 179
+C ++ +Y+FGG N + LD S + W R G PS K +
Sbjct: 94 SCAVCVDRVLYLFGG---HHSRGNTNKFYMLDSRSTDRVLQWERIDCQGIPPSSKDKLGV 150
Query: 180 VVYKDLLVLFGGW--------------TRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVT 225
VYK+ L+ FGG+ S + P + D +H W+ +T
Sbjct: 151 WVYKNKLIFFGGYGYLPEDKVLGTFEFDETSFWNSSHPRGWNDHVHILDTETFTWSQPIT 210
Query: 226 T-HGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRG 284
T P P A H+ + ++ VFGG +M ND+ L+L+ W W++ G P R
Sbjct: 211 TGKAPSPRAAHACATVGNRGFVFGGRYRDARM-NDLHYLNLDTWEWNELIPQGICPVGRS 269
Query: 285 GQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELWCHPA 344
S + + + GG DAW + W ++ + P LW H A
Sbjct: 270 WHSLTPVSSDHLFLFGGFTTDKQPLSDAWTYCISKNEW----IQFNHPYTEKPRLW-HTA 324
Query: 345 C 345
C
Sbjct: 325 C 325
Score = 50.1 bits (118), Expect = 7e-06
Identities = 49/150 (32%), Positives = 72/150 (48%), Gaps = 18/150 (12%)
Query: 105 ESRTYPYP---GTPITQRFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEW 161
E+ T+ P G + R +H AC N+ +VFGG + +A NDL L+L++ EW
Sbjct: 201 ETFTWSQPITTGKAPSPRAAH-ACATVGNRG-FVFGGRYR---DARMNDLHYLNLDTWEW 255
Query: 162 IRPLASGSYPSPKAGATLV-VYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWW 220
+ G P ++ +L V D L LFGG+T QP + TY SKN W
Sbjct: 256 NELIPQGICPVGRSWHSLTPVSSDHLFLFGGFTTDK-----QP---LSDAWTYCISKNEW 307
Query: 221 NCIVTTHGPPPMAGHSSCVIDD-KMIVFGG 249
+ P H++C D+ ++IVFGG
Sbjct: 308 IQFNHPYTEKPRLWHTACASDEGEVIVFGG 337
Score = 43.1 bits (100), Expect = 9e-04
Identities = 48/227 (21%), Positives = 82/227 (36%), Gaps = 44/227 (19%)
Query: 133 MYVFGGCTQSSCNAAFN------DLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLL 186
M+V+GG + ++ +LW ++ + W + G P +G+ V +L
Sbjct: 44 MFVWGGYKSNQVRGLYDFYLPREELWIYNMETGRWKKINTEGDVPPSMSGSCAVCVDRVL 103
Query: 187 VLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSC-VIDDKMI 245
LFGG + +F+ + W I PP V +K+I
Sbjct: 104 YLFGGH-----HSRGNTNKFYMLDSRSTDRVLQWERIDCQGIPPSSKDKLGVWVYKNKLI 158
Query: 246 VFGG----------------------SLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPR 283
FGG S R ++ V +LD E + WS+P +G +P PR
Sbjct: 159 FFGGYGYLPEDKVLGTFEFDETSFWNSSHPRGWNDHVHILDTETFTWSQPITTGKAPSPR 218
Query: 284 GGQSQIVIDDATILILGGCGGPNALFKDAWLLHMH---SGPWAWQPL 327
+ + + + GG ++DA + +H W W L
Sbjct: 219 AAHACATVGNRG-FVFGG------RYRDARMNDLHYLNLDTWEWNEL 258
>gi|7019405 host cell factor C2 [Homo sapiens]
Length = 792
Score = 70.1 bits (170), Expect = 7e-12
Identities = 52/179 (29%), Positives = 76/179 (42%), Gaps = 30/179 (16%)
Query: 113 GTPITQRFSHSACYYDANQS----MYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASG 168
G + R SH+A Y S MYVFGG C A +DLW+LDL + W +P G
Sbjct: 184 GVVPSPRESHTAVIYCKKDSGSPKMYVFGGM----CGARLDDLWQLDLETMSWSKPETKG 239
Query: 169 SYPSPKAGATLVVYKDLLVLFGGW-------TRPSPYPLHQPERFFDEIHTYSPSKNWWN 221
+ P P++ T V + + +FGGW T SP+ R + W
Sbjct: 240 TVPLPRSLHTASVIGNKMYIFGGWVPHKGENTETSPHDCEW--RCTSSFSYLNLDTTEWT 297
Query: 222 CIVT-------THGPPPMAGHSSCVIDDKMIVFGG------SLGSRQMSNDVWVLDLEQ 267
+V+ P P AGH + I ++ + G +L S+ D+W LD E+
Sbjct: 298 TLVSDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSGRDGYKKALNSQVCCKDLWYLDTEK 356
Score = 64.7 bits (156), Expect = 3e-10
Identities = 54/182 (29%), Positives = 81/182 (44%), Gaps = 20/182 (10%)
Query: 135 VFGGCTQSSCNAAFNDLWRLDLNSKEWIR----PLASGSYPSPKAGATLVVYKDLLVLFG 190
VFGG + + N+L+ L + W + P SG P P+ G + +Y + LFG
Sbjct: 86 VFGGMVEYGRYS--NELYELQASRWLWKKVKPHPPPSGLPPCPRLGHSFSLYGNKCYLFG 143
Query: 191 GWTRPSPYPLHQPERFFDEIHT----YSPSKNWWNCIVTTHG-PPPMAGHSSCVI----- 240
G S + R+ ++ + + W+ VT P P H++ +
Sbjct: 144 GLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGVVPSPRESHTAVIYCKKDS 203
Query: 241 -DDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDATILIL 299
KM VFGG G+R +D+W LDLE +WSKP G P PR + VI + + I
Sbjct: 204 GSPKMYVFGGMCGARL--DDLWQLDLETMSWSKPETKGTVPLPRSLHTASVIGN-KMYIF 260
Query: 300 GG 301
GG
Sbjct: 261 GG 262
Score = 59.3 bits (142), Expect = 1e-08
Identities = 38/126 (30%), Positives = 58/126 (46%), Gaps = 15/126 (11%)
Query: 167 SGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKN-WWNCIVT 225
+G P + G V ++L+++FGG E DE+H Y+ + N W+ V
Sbjct: 16 TGPVPRARHGHRAVAIRELMIIFGGGN----------EGIADELHVYNTATNQWFLPAVR 65
Query: 226 THGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSK----PNISGPSPH 281
PP A H +++VFGG + + SN+++ L +W W K P SG P
Sbjct: 66 GDIPPGCAAHGFVCDGTRILVFGGMVEYGRYSNELYELQASRWLWKKVKPHPPPSGLPPC 125
Query: 282 PRGGQS 287
PR G S
Sbjct: 126 PRLGHS 131
Score = 45.4 bits (106), Expect = 2e-04
Identities = 34/126 (26%), Positives = 54/126 (42%), Gaps = 7/126 (5%)
Query: 214 SPSKNWWNCIVTTHGPPPMA--GHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWS 271
+PS W + + GP P A GH + I + MI+FGG G+ +++++ V + W
Sbjct: 3 APSLLNWRRVSSFTGPVPRARHGHRAVAIRELMIIFGG--GNEGIADELHVYNTATNQWF 60
Query: 272 KPNISGPSPHPRGGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVEN 331
P + G P P V D IL+ GG + L + + W W+ +K
Sbjct: 61 LPAVRGDIP-PGCAAHGFVCDGTRILVFGGMVEYGRYSNE--LYELQASRWLWKKVKPHP 117
Query: 332 EEHGAP 337
G P
Sbjct: 118 PPSGLP 123
>gi|16945972 kelch domain containing 3 [Homo sapiens]
Length = 382
Score = 67.4 bits (163), Expect = 4e-11
Identities = 64/248 (25%), Positives = 100/248 (40%), Gaps = 30/248 (12%)
Query: 119 RFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGAT 178
R+ HS D ++ T+ +CN L+ D+N+ +W P SG+ P + G +
Sbjct: 77 RYGHSTVLIDDTVLLWGGRNDTEGACNV----LYAFDVNTHKWFTPRVSGTVPGARDGHS 132
Query: 179 LVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAG-HSS 237
V ++ +FGG+ + Q + F ++IH S W I T P HS+
Sbjct: 133 ACVLGKIMYIFGGYEQ-------QADCFSNDIHKLDTSTMTWTLICTKGSPARWRDFHSA 185
Query: 238 CVIDDKMIVFGG---SLGSRQMSNDVW-----VLDLEQWAWSKPNISGPSP-HPRGGQSQ 288
++ M VFGG G +N+++ V D AW P+P P G +S
Sbjct: 186 TMLGSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEAWLD---CPPTPVLPEGRRSH 242
Query: 289 IVID-DATILILGGCGGP-NALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELWCHPACR 346
+ + I GG N F D W + S W K+E + G C
Sbjct: 243 SAFGYNGELYIFGGYNARLNRHFHDLWKFNPVSFTWK----KIEPKGKGPCPRRRQCCCI 298
Query: 347 VGQCVVVF 354
VG +V+F
Sbjct: 299 VGDKIVLF 306
Score = 59.3 bits (142), Expect = 1e-08
Identities = 53/210 (25%), Positives = 89/210 (42%), Gaps = 7/210 (3%)
Query: 113 GTPITQRFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPS 172
GT R HSAC + MY+FGG Q + + ND+ +LD ++ W GS
Sbjct: 122 GTVPGARDGHSACVL--GKIMYIFGGYEQQA-DCFSNDIHKLDTSTMTWTLICTKGSPAR 178
Query: 173 PKAGATLVVYKDLLVLFGGWT-RPSPYPLHQPERFFDEIHTYSP-SKNWWNCIVTTHGPP 230
+ + + + +FGG R P+ + E + + I + ++ W +C T P
Sbjct: 179 WRDFHSATMLGSHMYVFGGRADRFGPFHSNN-EIYCNRIRVFDTRTEAWLDCPPTPVLPE 237
Query: 231 PMAGHSSCVIDDKMIVFGG-SLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQI 289
HS+ + ++ +FGG + + +D+W + + W K G P PR Q
Sbjct: 238 GRRSHSAFGYNGELYIFGGYNARLNRHFHDLWKFNPVSFTWKKIEPKGKGPCPRRRQCCC 297
Query: 290 VIDDATILILGGCGGPNALFKDAWLLHMHS 319
++ D +L G P D + L HS
Sbjct: 298 IVGDKIVLFGGTSPSPEEGLGDEFDLIDHS 327
Score = 50.4 bits (119), Expect = 6e-06
Identities = 34/88 (38%), Positives = 45/88 (51%), Gaps = 6/88 (6%)
Query: 112 PGTPITQ--RFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGS 169
P TP+ R SHSA Y N +Y+FGG + N F+DLW+ + S W + G
Sbjct: 230 PPTPVLPEGRRSHSAFGY--NGELYIFGGYN-ARLNRHFHDLWKFNPVSFTWKKIEPKGK 286
Query: 170 YPSPKAGATLVVYKDLLVLFGGWTRPSP 197
P P+ + D +VLFGG T PSP
Sbjct: 287 GPCPRRRQCCCIVGDKIVLFGG-TSPSP 313
>gi|21314675 kelch domain containing 4 [Homo sapiens]
Length = 520
Score = 65.5 bits (158), Expect = 2e-10
Identities = 56/210 (26%), Positives = 94/210 (44%), Gaps = 31/210 (14%)
Query: 114 TPITQRFSHSACYY-DANQSMYVFGGCTQSSCNAAF---NDLWRLDLNSKEWIRPLASGS 169
+P +R +H A ++VFGG S F DLW L L +K W + ++G
Sbjct: 114 SPPPRRCAHQAVVVPQGGGQLWVFGGEFASPNGEQFYHYKDLWVLHLATKTWEQVKSTGG 173
Query: 170 YPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQPER---FFDEIHTYSPSKNWWNCIVTT 226
PS ++G +V +K L+LFGG+ H+ R ++++++ ++ W+ + +
Sbjct: 174 -PSGRSGHRMVAWKRQLILFGGF--------HESTRDYIYYNDVYAFNLDTFTWSKLSPS 224
Query: 227 H-GPPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDV---------WVLDLE-----QWAWS 271
GP P +G V IV G +++ DV ++L E +W W+
Sbjct: 225 GTGPTPRSGCQMSVTPQGGIVVYGGYSKQRVKKDVDKGTRHSDMFLLKPEDGREDKWVWT 284
Query: 272 KPNISGPSPHPRGGQSQIVIDDATILILGG 301
+ N SG P PR G S + + L GG
Sbjct: 285 RMNPSGVKPTPRSGFSVAMAPNHQTLFFGG 314
Score = 56.2 bits (134), Expect = 1e-07
Identities = 47/203 (23%), Positives = 82/203 (40%), Gaps = 11/203 (5%)
Query: 106 SRTYPYPGTPITQRFSHSACYYDANQSMYVFGG-CTQSSCNAAFNDLWRLDLNSKEWIRP 164
++T P P + R + S + + +FGG +N+L+ + W +
Sbjct: 51 TQTVELPCPPPSPRLNASLSVHPEKDELILFGGEYFNGQKTFLYNELYVYNTRKDTWTKV 110
Query: 165 LASGSYPSPKAGATLVVYK---DLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWN 221
P A +VV + L V G + P+ + + ++ + W
Sbjct: 111 DIPSPPPRRCAHQAVVVPQGGGQLWVFGGEFASPNGEQFYH----YKDLWVLHLATKTWE 166
Query: 222 CIVTTHGPPPMAGHSSCVIDDKMIVFGGSLGSRQ---MSNDVWVLDLEQWAWSKPNISGP 278
+ +T GP +GH ++I+FGG S + NDV+ +L+ + WSK + SG
Sbjct: 167 QVKSTGGPSGRSGHRMVAWKRQLILFGGFHESTRDYIYYNDVYAFNLDTFTWSKLSPSGT 226
Query: 279 SPHPRGGQSQIVIDDATILILGG 301
P PR G V I++ GG
Sbjct: 227 GPTPRSGCQMSVTPQGGIVVYGG 249
Score = 40.4 bits (93), Expect = 0.006
Identities = 28/92 (30%), Positives = 47/92 (51%), Gaps = 13/92 (14%)
Query: 242 DKMIVFGGSLGSRQMS---NDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVI---DDAT 295
D++I+FGG + Q + N+++V + + W+K +I PSP PR Q V+
Sbjct: 76 DELILFGGEYFNGQKTFLYNELYVYNTRKDTWTKVDI--PSPPPRRCAHQAVVVPQGGGQ 133
Query: 296 ILILGG-CGGPNAL----FKDAWLLHMHSGPW 322
+ + GG PN +KD W+LH+ + W
Sbjct: 134 LWVFGGEFASPNGEQFYHYKDLWVLHLATKTW 165
>gi|47717139 leucine-zipper-like transcription regulator 1 [Homo
sapiens]
Length = 840
Score = 62.8 bits (151), Expect = 1e-09
Identities = 61/244 (25%), Positives = 95/244 (38%), Gaps = 21/244 (8%)
Query: 118 QRFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGA 177
+R H+ Y ++YVFGG + NDL R D+ W R +G+ P+P+
Sbjct: 67 RRSKHTVVAY--KDAIYVFGG---DNGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHH 121
Query: 178 TLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSS 237
+ VVY + +FGG+T Y + D + W + P + H +
Sbjct: 122 SAVVYGSSMFVFGGYT-GDIYSNSNLKNKNDLFEYKFATGQWTEWKIEGRLPVARSAHGA 180
Query: 238 CVIDDKMIVFGGSLGSRQMSNDVWVL---DLEQWAWSKPNISGPSPHPRGGQSQIVIDDA 294
V DK+ +F G G+ ++ ND+W + D E W + SG P V D
Sbjct: 181 TVYSDKLWIFAGYDGNARL-NDMWTIGLQDRELTCWEEVAQSGEIPPSCCNFPVAVCRDK 239
Query: 295 TILILGGCGG--PNALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELWCHPACRVGQCVV 352
+ G G N LF+ W + E+ G+P P R G +V
Sbjct: 240 MFVFSGQSGAKITNNLFQ------FEFKDKTWTRIPTEHLLRGSPP---PPQRRYGHTMV 290
Query: 353 VFSQ 356
F +
Sbjct: 291 AFDR 294
Score = 53.9 bits (128), Expect = 5e-07
Identities = 54/209 (25%), Positives = 81/209 (38%), Gaps = 22/209 (10%)
Query: 113 GTPITQRFSHSACYYDANQSMYVFGGCT----QSSCNAAFNDLWRLDLNSKEWIRPLASG 168
GTP R+ HSA Y SM+VFGG T +S NDL+ + +W G
Sbjct: 112 GTPPAPRYHHSAVVY--GSSMFVFGGYTGDIYSNSNLKNKNDLFEYKFATGQWTEWKIEG 169
Query: 169 SYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHG 228
P ++ VY D L +F G+ + D T W +
Sbjct: 170 RLPVARSAHGATVYSDKLWIFAGYDGNARLNDMWTIGLQDRELTC-----WEEVAQSGEI 224
Query: 229 PPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNI------SGPSPHP 282
PP V DKM VF G G++ ++N+++ + + W++ S P P
Sbjct: 225 PPSCCNFPVAVCRDKMFVFSGQSGAK-ITNNLFQFEFKDKTWTRIPTEHLLRGSPPPPQR 283
Query: 283 RGGQSQIVIDDATILILGGCGG---PNAL 308
R G + + D + + GG PN L
Sbjct: 284 RYGHTMVAF-DRHLYVFGGAADNTLPNEL 311
>gi|195963410 MEF2 activating motif and SAP domain containing
transcriptional regulator isoform 1 [Homo sapiens]
Length = 415
Score = 58.2 bits (139), Expect = 3e-08
Identities = 80/264 (30%), Positives = 110/264 (41%), Gaps = 39/264 (14%)
Query: 363 PLSPSLNSRPSPISATPPALVPETREYRSQSPVRS-MDEAPCVNGRWGTLRPRA----QR 417
PL+P+L S +P +P L+PE EY P RS E+P ++ RW +PR +
Sbjct: 46 PLAPALPSGTAPFLFSPGVLLPEP-EY--CPPWRSPKKESPKISQRWRESKPRGNLTYHQ 102
Query: 418 QTPSGSREGSLSPARGDGSPI-LNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDL 476
P R+GS + + +GS + G SL GT S P SP TP P G
Sbjct: 103 YMPPEPRQGSRADPQAEGSALGPPGPSLWEGT----DSQQPHPRMKPSPLTP-CPPGVP- 156
Query: 477 KIGLSLAPRRGSLPDQKDLRLGSIDLNWDLK----PASSSNPMDGMDNRTVGGSMRHPPE 532
S P + L K L +L L+ P S + M + R GG+ PP
Sbjct: 157 --SPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSM--LLERMRGGA---PPR 209
Query: 533 QTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQS 592
+ P + AGA P ++L A + S PSA A+ PPL + +PG
Sbjct: 210 E----RPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSA-ASHRPPLPRAADTPG--- 261
Query: 593 LSSGETVPIPRPGPAQGDGHSLPP 616
T P P P PA +L P
Sbjct: 262 -----TAPAPTPTPAPAAAPALTP 280
Score = 32.7 bits (73), Expect = 1.2
Identities = 72/269 (26%), Positives = 95/269 (35%), Gaps = 46/269 (17%)
Query: 273 PNISGPSPHPRGGQSQIV-IDDATILILGGC----GGPNALFKDAWLLHMHSGPWAWQPL 327
P + PSP P + Q + +++ T+ L G P + K L M G +
Sbjct: 153 PGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERP 212
Query: 328 KVENEEHGAPELWCH-------PACRVGQCVVVFSQAPSGRAPLSPSLNS-------RPS 373
K E+ A W A R G V A S R PL + ++ P+
Sbjct: 213 KPRREDSPAGAPWPRLKPKALAAARRQGS---VKPSAASHRPPLPRAADTPGTAPAPTPT 269
Query: 374 PISATPPALVPE--------TREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSGSRE 425
P A PAL P T E Q +R P G L + + P
Sbjct: 270 PAPAAAPALTPSSGPGSAALTLEEELQEAIRRAQLLPN-RGIDDILEDQVEPDDP----- 323
Query: 426 GSLSPARGD--GS-PILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGLSL 482
L P D GS +L+ S G ++V SSL SP + SPS + D LS
Sbjct: 324 --LPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDPTDSLDWLEALSG 381
Query: 483 APRRGSLPD-----QKDLRLGSIDLNWDL 506
P GS P DL S WDL
Sbjct: 382 GPPLGSGPPPPSIFSADLSDSSSSRLWDL 410
>gi|145701025 multiple EGF-like-domains 8 [Homo sapiens]
Length = 2778
Score = 55.8 bits (133), Expect = 1e-07
Identities = 73/277 (26%), Positives = 109/277 (39%), Gaps = 48/277 (17%)
Query: 113 GTPITQRFSHSACYYDANQSMYVFGGCT-QSSCNAAFNDLWRLDLNSKEWIRPLASGSYP 171
GTP T + HSA Y++A S+YVFGG A +L+ L + W S
Sbjct: 1599 GTPPTGLYGHSAVYHEATDSLYVFGGFRFHVELAAPSPELYSLHCPDRTW-------SLL 1651
Query: 172 SPKAGATLVVYKDLLVLFGGWTRP-SPYPLHQPERF-FDEIHTYSPSKNWWNCIVTTHG- 228
+P GA +D + G +R P QP + F E+ W + T G
Sbjct: 1652 APSQGAK----RDRMRNVRGSSRGLGQVPGEQPGSWGFREVR---KKMALWAALAGTGGF 1704
Query: 229 ----------PPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNIS-- 276
P P H+S ++ D M+V GG + S+DV + + AW P+++
Sbjct: 1705 LEEISPHLKEPRPRLFHASALLGDTMVVLGGRSDPDEFSSDVLLYQVNCNAWLLPDLTRS 1764
Query: 277 ---GPSPHPRGGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVENEE 333
GP P + + + I GG GG AL + LL + P P ++ +
Sbjct: 1765 ASVGP-PMEESVAHAVAAVGSRLYISGGFGGV-ALGR---LLALTLPP---DPCRLLSSP 1816
Query: 334 HGAPE----LWCHPACRVGQCVVVFSQAPSGRAPLSP 366
+ WCH AC G + G +P SP
Sbjct: 1817 EACNQSGACTWCHGACLSGDQA---HRLGCGGSPCSP 1850
Score = 40.0 bits (92), Expect = 0.008
Identities = 32/140 (22%), Positives = 53/140 (37%), Gaps = 22/140 (15%)
Query: 166 ASGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVT 225
A+G++ SP LL +FGG ++ Y+ S N W
Sbjct: 231 AAGAFLSPPG---------LLAVFGG---------QDLNNALGDLVLYNFSANTWESWDL 272
Query: 226 THGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLD-LEQWAW---SKPNISGPSPH 281
+ P H + +++ GG L ++NDVW L + W + P S P
Sbjct: 273 SPAPAARHSHVAVAWAGSLVLMGGELADGSLTNDVWAFSPLGRGHWELLAPPASSSSGPP 332
Query: 282 PRGGQSQIVIDDATILILGG 301
G + ++DD + + GG
Sbjct: 333 GLAGHAAALVDDVWLYVSGG 352
Score = 35.8 bits (81), Expect = 0.14
Identities = 46/203 (22%), Positives = 77/203 (37%), Gaps = 25/203 (12%)
Query: 122 HSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKE-WIRPLASGSYPSPKAGATLV 180
H+A D + +YV GG T ++ +RLD S W + + +G P G ++V
Sbjct: 337 HAAALVD-DVWLYVSGGRTPHDLFSSGLFRFRLDSTSGGYWEQVIPAGGRPPAATGHSMV 395
Query: 181 VYK-DLLVLFGGWTRPSP----YPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGH 235
+ +L G RPS ++ E F + H ++ K GP A H
Sbjct: 396 FHAPSRALLVHGGHRPSTARFSVRVNSTELFHVDRHVWTTLKGRDGL----QGPRERAFH 451
Query: 236 SSCVIDDKMIVFGGSLGSRQMSNDV--------------WVLDLEQWAWSKPNISGPSPH 281
++ V+ + M+V+GG++ + WV E P P
Sbjct: 452 TASVLGNYMVVYGGNVHTHYQEEKCYEDGIFFYHLGCHQWVSGAELAPPGTPEGRAAPPS 511
Query: 282 PRGGQSQIVIDDATILILGGCGG 304
R V+ + +L+ GG G
Sbjct: 512 GRYSHVAAVLGGSVLLVAGGYSG 534
Score = 33.9 bits (76), Expect = 0.54
Identities = 36/159 (22%), Positives = 63/159 (39%), Gaps = 19/159 (11%)
Query: 174 KAGATLVVYKDL-LVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTH----- 227
+ G T+V D L +FGG L P+ ++ YS S+ W ++
Sbjct: 1443 RLGHTMVDGPDATLWMFGG--------LGLPQGLLGNLYRYSVSERRWTQMLAGAEDGGP 1494
Query: 228 GPPPMAGHSSCVID---DKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPR- 283
GP P + H++ + M + GG L + ++ D WVL+L W + P
Sbjct: 1495 GPSPRSFHAAAYVPAGRGAMYLLGG-LTAGGVTRDFWVLNLTTLQWRQEKAPQTVELPAV 1553
Query: 284 GGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPW 322
G + ++L++GG N + + +G W
Sbjct: 1554 AGHTLTARRGLSLLLVGGYSPENGFNQQLLEYQLATGTW 1592
>gi|33695109 Rab9 effector protein with kelch motifs [Homo sapiens]
Length = 372
Score = 55.5 bits (132), Expect = 2e-07
Identities = 42/149 (28%), Positives = 65/149 (43%), Gaps = 14/149 (9%)
Query: 105 ESRTYPYP---GTPITQRFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEW 161
E+RT+ P P + R H++ NQ +YVFGG + + L D N+ W
Sbjct: 122 ETRTWTTPEVTSPPPSPRTFHTSSAAIGNQ-LYVFGGGERGAQPVQDTKLHVFDANTLTW 180
Query: 162 IRPLASGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWN 221
+P G+ PSP+ G +V L + GG +RF+D++H S W
Sbjct: 181 SQPETLGNPPSPRHGHVMVAAGTKLFIHGGLA---------GDRFYDDLHCIDISDMKWQ 231
Query: 222 CIVTTHGPPP-MAGHSSCVIDDKMIVFGG 249
+ T P A HS+ + + +FGG
Sbjct: 232 KLNPTGAAPAGCAAHSAVAMGKHVYIFGG 260
Score = 54.3 bits (129), Expect = 4e-07
Identities = 68/268 (25%), Positives = 100/268 (37%), Gaps = 37/268 (13%)
Query: 108 TYPYPGTPITQRFSHSACYYDA-----NQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWI 162
T PG R HS Y +++ GG N +F+D+ +DL +W
Sbjct: 20 TLTVPGDSPCARVGHSCSYLPPVGNAKRGKVFIVGGANP---NRSFSDVHTMDLGKHQWD 76
Query: 163 RPLASGSYPSPKAGATL-VVYKDLLVLFGGWTRPSPYPLHQ---PERFFDEIHTYSPSKN 218
G P + + + D + +FGG + Q PE ++
Sbjct: 77 LDTCKGLLPRYEHASFIPSCTPDRIWVFGGANQSGNRNCLQVLNPE-----------TRT 125
Query: 219 WWNCIVTTHGPPPMAGH-SSCVIDDKMIVFGGSLGSRQMSND--VWVLDLEQWAWSKPNI 275
W VT+ P P H SS I +++ VFGG Q D + V D WS+P
Sbjct: 126 WTTPEVTSPPPSPRTFHTSSAAIGNQLYVFGGGERGAQPVQDTKLHVFDANTLTWSQPET 185
Query: 276 SGPSPHPRGGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEHG 335
G P PR G +V + I GG G + + D + + WQ L G
Sbjct: 186 LGNPPSPRHGH-VMVAAGTKLFIHGGLAG-DRFYDDLHCIDI--SDMKWQKL----NPTG 237
Query: 336 APELWC--HPACRVGQCVVVF-SQAPSG 360
A C H A +G+ V +F P+G
Sbjct: 238 AAPAGCAAHSAVAMGKHVYIFGGMTPAG 265
Score = 53.9 bits (128), Expect = 5e-07
Identities = 58/234 (24%), Positives = 93/234 (39%), Gaps = 21/234 (8%)
Query: 100 GNIQWESRTYPYPGTPITQRFSHSACYYDANQS-MYVFGGCTQSSCNAAFNDLWRLDLNS 158
G QW+ T + R+ H++ ++VFGG QS N L L+ +
Sbjct: 71 GKHQWDLDTCK----GLLPRYEHASFIPSCTPDRIWVFGGANQSGNR---NCLQVLNPET 123
Query: 159 KEWIRPLASGSYPSPKAGATL-VVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSK 217
+ W P + PSP+ T + L +FGG R + QP + ++H + +
Sbjct: 124 RTWTTPEVTSPPPSPRTFHTSSAAIGNQLYVFGGGERGA-----QPVQD-TKLHVFDANT 177
Query: 218 NWWNCIVTTHGPP-PMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNIS 276
W+ T PP P GH K+ + GG G R +D+ +D+ W K N +
Sbjct: 178 LTWSQPETLGNPPSPRHGHVMVAAGTKLFIHGGLAGDR-FYDDLHCIDISDMKWQKLNPT 236
Query: 277 GPSPHPRGGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVE 330
G +P S + + + I GG AL + H+ W LK +
Sbjct: 237 GAAPAGCAAHSAVAM-GKHVYIFGGMTPAGAL---DTMYQYHTEEQHWTLLKFD 286
>gi|44917619 kelch domain containing 10 [Homo sapiens]
Length = 442
Score = 54.3 bits (129), Expect = 4e-07
Identities = 52/186 (27%), Positives = 82/186 (44%), Gaps = 23/186 (12%)
Query: 130 NQSMYVFGGCTQSSCNAA---------FNDLWRLDLNSKEWIRPLASGSYPSPKAGATLV 180
N ++YVFGG + F +LWR + W + G P A +LV
Sbjct: 101 NTNLYVFGGYNPDYDESGGPDNEDYPLFRELWRYHFATGVWHQMGTDGYMPRELASMSLV 160
Query: 181 VYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPP--MAGHSSC 238
++ + L++FGG P E +++H + W +++ G P + G +
Sbjct: 161 LHGNNLLVFGGTGIPF------GESNGNDVHVCNVKYKRW-ALLSCRGKKPSRIYGQAMA 213
Query: 239 VIDDKMIVFGGSLGSRQMSNDVWVLDL--EQWAWSKP-NISGPSPHPRGGQSQIVIDDAT 295
+I+ + VFGG+ G S D+ LDL +W KP N+S P R + +I D
Sbjct: 214 IINGSLYVFGGTTG-YIYSTDLHKLDLNTREWTQLKPNNLSCDLPEER-YRHEIAHDGQR 271
Query: 296 ILILGG 301
I ILGG
Sbjct: 272 IYILGG 277
Score = 53.1 bits (126), Expect = 9e-07
Identities = 46/159 (28%), Positives = 70/159 (44%), Gaps = 19/159 (11%)
Query: 130 NQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEW--IRPL-ASGSYPSPKAGATLVVYKDLL 186
N S+YVFGG T + DL +LDLN++EW ++P S P + + +
Sbjct: 216 NGSLYVFGGTTGYIYST---DLHKLDLNTREWTQLKPNNLSCDLPEERYRHEIAHDGQRI 272
Query: 187 VLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHG-----PPPMAGHSSCVID 241
+ GG T + Y L++ IH Y+ N W I T P HS I
Sbjct: 273 YILGGGTSWTAYSLNK-------IHAYNLETNAWEEIATKPHEKIGFPAARRCHSCVQIK 325
Query: 242 DKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSP 280
+ + + GG G + D+W L+L+ + W K + P P
Sbjct: 326 NDVFICGGYNGE-VILGDIWKLNLQTFQWVKLPATMPEP 363
Score = 37.7 bits (86), Expect = 0.037
Identities = 46/200 (23%), Positives = 77/200 (38%), Gaps = 13/200 (6%)
Query: 171 PSPKAGATLVVYKDLLVLFGGWTRP---SPYPLHQPERFFDEIHTYSPSKNWWNCIVTT- 226
P ++G V L +FGG+ S P ++ F E+ Y + W+ + T
Sbjct: 89 PPARSGHRCVADNTNLYVFGGYNPDYDESGGPDNEDYPLFRELWRYHFATGVWHQMGTDG 148
Query: 227 HGPPPMAGHSSCVIDDKMIVFGGS---LGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPR 283
+ P +A S + + ++VFGG+ G NDV V +++ W+ + G P
Sbjct: 149 YMPRELASMSLVLHGNNLLVFGGTGIPFGESN-GNDVHVCNVKYKRWALLSCRGKKPSRI 207
Query: 284 GGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEHGAP-ELWCH 342
GQ+ +I+ + + GG L + W LK N P E + H
Sbjct: 208 YGQAMAIINGSLYVF----GGTTGYIYSTDLHKLDLNTREWTQLKPNNLSCDLPEERYRH 263
Query: 343 PACRVGQCVVVFSQAPSGRA 362
GQ + + S A
Sbjct: 264 EIAHDGQRIYILGGGTSWTA 283
>gi|20143482 melanoma antigen family E, 1 [Homo sapiens]
Length = 957
Score = 50.4 bits (119), Expect = 6e-06
Identities = 78/299 (26%), Positives = 101/299 (33%), Gaps = 43/299 (14%)
Query: 343 PACRVGQCVVVFSQAPSGRAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAP 402
P G C V A GR SRP S P VP T S V S P
Sbjct: 118 PTISKGLCTSVTLAASEGRN------TSRPPTSSEEPSTSVPPTA-----SEVPSTSLPP 166
Query: 403 CVNGRWGTLRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAA--VGGSSLDSPV 460
T P + PS S + P G + +L PGT+ L + V
Sbjct: 167 TPGEGTSTSVPPTAYEGPSTSVVPT--PDEGPSTSVLPTPGEGPGTSVPLAATEGLSTSV 224
Query: 461 QAI---SPST---PSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNP 514
QA PST P+A EG + + P R P + + PA+S
Sbjct: 225 QATPDEGPSTSVPPTATEG----LSTPVPPTRDEGPSTSVPATPGEGPSTSVLPAASDGQ 280
Query: 515 MDGM-DNRTVGGSMRHPPEQTNGVHT--------------PPHVASALAGAVSPGALRRS 559
+ R G S PP T G+ T PP L+ +V P A
Sbjct: 281 SISLVPTRGKGSSTSVPPTATEGLSTSVQPTAGEGSSTSVPPTPGGGLSTSVPPTATEEL 340
Query: 560 LEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVPIPRPGPAQGDGHSLPPIA 618
++ +GPS S P G S P + S S +VP P P +G + P A
Sbjct: 341 STSVPPTPGEGPSTSVLPIPGEGLSTSVPPTASDGSDTSVP---PTPGEGASTLVQPTA 396
>gi|46410931 attractin-like 1 [Homo sapiens]
Length = 1379
Score = 50.1 bits (118), Expect = 7e-06
Identities = 45/183 (24%), Positives = 82/183 (44%), Gaps = 14/183 (7%)
Query: 87 HQCYHGFMKAVQEGNIQWESRTYPYP---GTPITQRFSHSACYYDANQSMYVFGGCTQSS 143
+ +G+ ++QE +I S T+ P G + + H++ Y + +S+YV GG
Sbjct: 434 YSAIYGYTSSIQEYHIS--SNTWLVPETKGAIVQGGYGHTSVYDEITKSIYVHGGYKALP 491
Query: 144 CN--AAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLH 201
N +DL++ ++N+K W SG + + V+ +++FGG T +
Sbjct: 492 GNKYGLVDDLYKYEVNTKTWTILKESGF---ARYLHSAVLINGAMLIFGGNTHNDTSLSN 548
Query: 202 QPERFFDEIHTYSPSKNWWNCIV--TTHGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSND 259
+ F + Y + + W + H GHS+ VI+ M +FGG S + ND
Sbjct: 549 GAKCFSADFLAYDIACDEWKILPKPNLHRDVNRFGHSAVVINGSMYIFGGF--SSVLLND 606
Query: 260 VWV 262
+ V
Sbjct: 607 ILV 609
Score = 41.2 bits (95), Expect = 0.003
Identities = 41/191 (21%), Positives = 78/191 (40%), Gaps = 25/191 (13%)
Query: 149 NDLWR-----LDLNSKE--WIRPLASGSYPSP-KAGATLVVYKDLLVLFGGWTRPSPYPL 200
ND W+ L++ S E WI P PS +A V++ + + GG+T
Sbjct: 272 NDSWQGPDCSLNVPSTESYWILPNVKPFSPSVGRASHKAVLHGKFMWVIGGYTFNYSS-- 329
Query: 201 HQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVIDDKMIVFGGSLGSR--QMSN 258
F + Y+ + WN + GP GHS + + + ++GG + + +++
Sbjct: 330 ------FQMVLNYNLESSIWNVGTPSRGPLQRYGHSLALYQENIFMYGGRIETNDGNVTD 383
Query: 259 DVWVLDLEQWAWS--KPNISG-PSPHPRGGQSQIVID----DATILILGGCGGPNALFKD 311
++WV ++ +WS P + G + G S +++ D ++I+ G
Sbjct: 384 ELWVFNIHSQSWSTKTPTVLGHGQQYAVEGHSAHIMELDSRDVVMIIIFGYSAIYGYTSS 443
Query: 312 AWLLHMHSGPW 322
H+ S W
Sbjct: 444 IQEYHISSNTW 454
Score = 32.0 bits (71), Expect = 2.0
Identities = 15/52 (28%), Positives = 29/52 (55%), Gaps = 5/52 (9%)
Query: 113 GTPIT---QRFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEW 161
GTP QR+ HS Y N ++++GG +++ ++LW +++S+ W
Sbjct: 346 GTPSRGPLQRYGHSLALYQEN--IFMYGGRIETNDGNVTDELWVFNIHSQSW 395
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 49.7 bits (117), Expect = 9e-06
Identities = 69/284 (24%), Positives = 103/284 (36%), Gaps = 31/284 (10%)
Query: 357 APSGRAPLSPSLNSRPSPISATPPALV--PETREYRSQSPVRSMDEAPCVNGR-WGTLRP 413
+P G P +PS P+P + TPP+ P + + P G T P
Sbjct: 995 SPKG-GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLP 1053
Query: 414 RAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGT---AAVGGSSLDSPVQAISP--STP 468
+ TP+ + SP G +P L G P + GG + SP A P +TP
Sbjct: 1054 KGAPTTPAATLP---SPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATP 1110
Query: 469 SAPEGYDLKIGLSLAPRRGSL-------PDQKDLRLGSIDLNWDLKPASSS-NPMDGMDN 520
+P+G GL+ P +G+ P K PA++ +P G+
Sbjct: 1111 PSPKG-----GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT 1165
Query: 521 RTVGGS----MRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAA 576
G+ PP G+ TP + A +P + + L + A+
Sbjct: 1166 PPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1225
Query: 577 LSPPLGSSPGSPGSQSLSSGETVPIPRPGPA--QGDGHSLPPIA 618
SP G + SP + T P P+ GPA G PP A
Sbjct: 1226 PSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAA 1269
Score = 47.4 bits (111), Expect = 5e-05
Identities = 66/273 (24%), Positives = 102/273 (37%), Gaps = 45/273 (16%)
Query: 357 APSGRAPLSPSLNSRPSPISATPPALVPE----TREYRSQSPVRSMDEAPCVNGRWGTLR 412
+P G P +PS P P +ATPP+ P+ T ++ +P P G T
Sbjct: 1089 SPKG-GPATPSPKGAPMPPAATPPS--PKGGLATPPHKG-APTTPAATPPSPKGGLATPP 1144
Query: 413 PRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGT---AAVGGSSLDSPVQAISP--ST 467
P+ TP+ + SP G +P G +P + GG + SP A + +T
Sbjct: 1145 PKGAPTTPAATPP---SPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1201
Query: 468 PSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGS- 526
P +P+G GL+ +G+ A+ +P G+ + G+
Sbjct: 1202 PPSPKG-----GLATPSPKGAPTTPA---------------ATPPSPKGGLATPSPKGAP 1241
Query: 527 ---MRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGS 583
PP G TPP + A +P +L+ L KG A ++PP S
Sbjct: 1242 TTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGL---ATPPHKGAPNPAVVTPP--S 1296
Query: 584 SPGSPGSQSLSSGETVPIPRPGPAQGDGHSLPP 616
G P + T P P +G + PP
Sbjct: 1297 PKGGPATSPPKGAPTPPAATPPSPKGSPGTPPP 1329
Score = 45.4 bits (106), Expect = 2e-04
Identities = 64/268 (23%), Positives = 91/268 (33%), Gaps = 23/268 (8%)
Query: 357 APSGRAPLSPSLNSRPSPISATPPALV--PETREYRSQSPVRSMDEAPCVNGRWGTLRPR 414
AP G P SPS P+P +ATPP+ P T + +P P G T P+
Sbjct: 926 APKG-IPASPSPKGAPTPPAATPPSPKGGPATPSPK-WAPTPPAATPPSPKGGPATPSPK 983
Query: 415 AQRQTPSGSREGSLSPARGDGSPILNGGSLSPGT----------AAVGGSSLDSPVQAIS 464
P+ + SP G +P G P A +P A
Sbjct: 984 GAPTPPAATPP---SPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATP 1040
Query: 465 PSTPSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSS-NPMDGMDNRTV 523
PS +P L G P +LP K PA++ +P G +
Sbjct: 1041 PSPKGSPAATPLPKGAPTTPA-ATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP 1099
Query: 524 GGS----MRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSP 579
G+ PP G+ TPPH + A +P + + L + A+ SP
Sbjct: 1100 KGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1159
Query: 580 PLGSSPGSPGSQSLSSGETVPIPRPGPA 607
G + P + T P P+ G A
Sbjct: 1160 KGGLATPPPKGAPTTPAATPPSPKGGLA 1187
Score = 39.3 bits (90), Expect = 0.013
Identities = 63/276 (22%), Positives = 99/276 (35%), Gaps = 43/276 (15%)
Query: 362 APLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPS 421
AP +PS S +++PPA+ P T Y+ + + P V P TP
Sbjct: 1570 APATPS-----SKEASSPPAVTPST--YKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPP 1622
Query: 422 GSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGLS 481
SP +G +P G SP V SSL +P++P K+G +
Sbjct: 1623 -------SPEKGPATPAPKGTPTSP---PVTPSSLKD--------SPTSPASVTCKMGAT 1664
Query: 482 LAPRRGSLPDQKDLRLGSIDLNWDL-KPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTP 540
+ LP +K G L L PA S P+ R + P + + +P
Sbjct: 1665 VPQASKGLPAKK----GPTALKEVLVAPAPESTPIITAPTR------KGPQTKKSSATSP 1714
Query: 541 PHVASALAGAVSPGALRR-------SLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSL 593
P A S G L ++ + ++KG AS + PL +
Sbjct: 1715 PICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLT 1774
Query: 594 SSGETVPIPRPGPAQGDGHSLPPIARRLGHHPPQSL 629
++ +P+P A PP++ L P +L
Sbjct: 1775 AAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTL 1810
Score = 35.8 bits (81), Expect = 0.14
Identities = 74/296 (25%), Positives = 111/296 (37%), Gaps = 37/296 (12%)
Query: 354 FSQAPSGRAPLSPSLNSRPSPISA-TPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLR 412
+ APS + L P + PSP A TPPA+ P S ++ P GT
Sbjct: 1590 YKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPP-----------SPEKGPATPAPKGT-- 1636
Query: 413 PRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPG-TAAVGGSSLDSPVQAISP-STP-- 468
P + TPS ++ SPA S G A G ++L + A +P STP
Sbjct: 1637 PTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPII 1696
Query: 469 SAP--EGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGS 526
+AP +G K + +P P K+ G + + PA G
Sbjct: 1697 TAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLS---TVAPAPLLPVQKDSSKTAKGKD 1753
Query: 527 MRHPPEQTNGVHTPPH--VASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSP-PLGS 583
H P+ G PP ++ L A L + E+ ++ P S L+P P+ +
Sbjct: 1754 ASHSPK---GPLAPPESKASTPLTAAAFEKVLPKP-ESASVSAAPSPPVSLPLAPSPVPT 1809
Query: 584 SPGSPGSQSLSSGETVPIPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKPLYQSM 639
P S G + P A D L P+ PP+ ++ G P +QS+
Sbjct: 1810 LPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLI------PPEPISGGVP-FQSV 1858
Score = 33.9 bits (76), Expect = 0.54
Identities = 63/269 (23%), Positives = 100/269 (37%), Gaps = 38/269 (14%)
Query: 357 APSGRAPLSPSLNSRPSPISATPPALVP--ETREYRSQSPVRSMDEAPCVNGRWGTLRPR 414
+P G P +P P+P +ATPP+L T ++ +P ++ P G T P+
Sbjct: 1250 SPKG-GPATPPPKGAPTPPAATPPSLKGGLATPPHKG-APNPAVVTPPSPKGGPATSPPK 1307
Query: 415 AQRQTPSGSREGSLSPARGDGSPILNGGSLSPGT---AAVGGSSLDS--PVQAISPSTPS 469
P+ + SP G+P G P + G +L + P P+TPS
Sbjct: 1308 GAPTPPAATPP---SPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPS 1364
Query: 470 APEGY-------DLKIGLSL---APRRG-SLPDQKDLRLGSIDLNWDLKPASSSNPMDGM 518
+ EG K G ++ +P+RG ++P K + K A ++ P+
Sbjct: 1365 SKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPAT-PVTRE 1423
Query: 519 DNRTVGGSMRHPPEQTN-GVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAAL 577
T PP T + P ++ G +P SSKG A+
Sbjct: 1424 GAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATP-------------SSKGDPTLPAV 1470
Query: 578 SPPLGSSPGSPGSQSLSSGETVPIPRPGP 606
+PP P +P + SS P P
Sbjct: 1471 TPPSPKEPPAPKQVATSSSPKKAPATPAP 1499
>gi|21450863 attractin isoform 2 [Homo sapiens]
Length = 1272
Score = 47.8 bits (112), Expect = 4e-05
Identities = 44/186 (23%), Positives = 83/186 (44%), Gaps = 10/186 (5%)
Query: 87 HQCYHGFMKAVQEGNIQWESRTYPYP-GTPITQRFSHSACYYDANQSMYVFGGCTQSSCN 145
H +G++ VQE ++ + + + G + + HS+ Y +++YV GG S N
Sbjct: 467 HCPLYGYISNVQEYDLDKNTWSILHTQGALVQGGYGHSSVYDHRTRALYVHGGYKAFSAN 526
Query: 146 --AAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQP 203
+DL+R D++++ W S + + T V+ +++FGG T H
Sbjct: 527 KYRLADDLYRYDVDTQMWTILKDSRFF---RYLHTAVIVSGTMLVFGGNTHNDTSMSHGA 583
Query: 204 ERFFDEIHTYSPSKNWWNCI--VTTHGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVW 261
+ F + Y + + W+ + H GHS+ + + M VFGG + + +D+
Sbjct: 584 KCFSSDFMAYDIACDRWSVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGF--NSLLLSDIL 641
Query: 262 VLDLEQ 267
V EQ
Sbjct: 642 VFTSEQ 647
Score = 32.0 bits (71), Expect = 2.0
Identities = 37/162 (22%), Positives = 69/162 (42%), Gaps = 13/162 (8%)
Query: 133 MYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLFGGW 192
M+V GG + ++ +N + DL S+EW+ S + + G +L +YKD + ++GG
Sbjct: 353 MWVVGGYMFN--HSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALYKDKIYMYGGK 410
Query: 193 TRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVIDDK-----MIVF 247
+ ++ F IH +++W + GHS+ ++ K M+V
Sbjct: 411 IDSTGNVTNELRVF--HIH----NESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVVMLVI 464
Query: 248 GGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQI 289
G ++V DL++ WS + G G S +
Sbjct: 465 FGHCPLYGYISNVQEYDLDKNTWSILHTQGALVQGGYGHSSV 506
Score = 30.4 bits (67), Expect = 6.0
Identities = 23/92 (25%), Positives = 35/92 (38%)
Query: 231 PMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIV 290
P A H + V + M V GG + + N V DL W N S + R G S +
Sbjct: 340 PRASHKAVVNGNIMWVVGGYMFNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLAL 399
Query: 291 IDDATILILGGCGGPNALFKDAWLLHMHSGPW 322
D + G + + + H+H+ W
Sbjct: 400 YKDKIYMYGGKIDSTGNVTNELRVFHIHNESW 431
>gi|21450861 attractin isoform 1 [Homo sapiens]
Length = 1429
Score = 47.8 bits (112), Expect = 4e-05
Identities = 44/186 (23%), Positives = 83/186 (44%), Gaps = 10/186 (5%)
Query: 87 HQCYHGFMKAVQEGNIQWESRTYPYP-GTPITQRFSHSACYYDANQSMYVFGGCTQSSCN 145
H +G++ VQE ++ + + + G + + HS+ Y +++YV GG S N
Sbjct: 467 HCPLYGYISNVQEYDLDKNTWSILHTQGALVQGGYGHSSVYDHRTRALYVHGGYKAFSAN 526
Query: 146 --AAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQP 203
+DL+R D++++ W S + + T V+ +++FGG T H
Sbjct: 527 KYRLADDLYRYDVDTQMWTILKDSRFF---RYLHTAVIVSGTMLVFGGNTHNDTSMSHGA 583
Query: 204 ERFFDEIHTYSPSKNWWNCI--VTTHGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVW 261
+ F + Y + + W+ + H GHS+ + + M VFGG + + +D+
Sbjct: 584 KCFSSDFMAYDIACDRWSVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGF--NSLLLSDIL 641
Query: 262 VLDLEQ 267
V EQ
Sbjct: 642 VFTSEQ 647
Score = 32.0 bits (71), Expect = 2.0
Identities = 37/162 (22%), Positives = 69/162 (42%), Gaps = 13/162 (8%)
Query: 133 MYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLFGGW 192
M+V GG + ++ +N + DL S+EW+ S + + G +L +YKD + ++GG
Sbjct: 353 MWVVGGYMFN--HSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALYKDKIYMYGGK 410
Query: 193 TRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVIDDK-----MIVF 247
+ ++ F IH +++W + GHS+ ++ K M+V
Sbjct: 411 IDSTGNVTNELRVF--HIH----NESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVVMLVI 464
Query: 248 GGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQI 289
G ++V DL++ WS + G G S +
Sbjct: 465 FGHCPLYGYISNVQEYDLDKNTWSILHTQGALVQGGYGHSSV 506
Score = 30.4 bits (67), Expect = 6.0
Identities = 23/92 (25%), Positives = 35/92 (38%)
Query: 231 PMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIV 290
P A H + V + M V GG + + N V DL W N S + R G S +
Sbjct: 340 PRASHKAVVNGNIMWVVGGYMFNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLAL 399
Query: 291 IDDATILILGGCGGPNALFKDAWLLHMHSGPW 322
D + G + + + H+H+ W
Sbjct: 400 YKDKIYMYGGKIDSTGNVTNELRVFHIHNESW 431
>gi|146219832 myosin light chain kinase 3 [Homo sapiens]
Length = 819
Score = 45.1 bits (105), Expect = 2e-04
Identities = 57/239 (23%), Positives = 88/239 (36%), Gaps = 44/239 (18%)
Query: 391 SQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAA 450
++ P +A + G L P + + +SP +GDG P P A
Sbjct: 184 AREPGEESQKADVLEGTAERLPPIRASGLGADPAQAVVSPGQGDGVP-------GPAQAF 236
Query: 451 VGGSSLDSPVQAISPSTPSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKP-- 508
G L + V+A +P TPS +L+ GL LAP G R+ + + ++ P
Sbjct: 237 PGHLPLPTKVEAKAPETPSE----NLRTGLELAPAPG--------RVNVVSPSLEVAPGA 284
Query: 509 ---ASSS----NPMDGMDNRTVGGSMRHP-----PEQTNGVH----TPPHVASALAGAVS 552
ASSS P++ T G + P P Q H TPP ++ + +
Sbjct: 285 GQGASSSRPDPEPLEEGTRLTPGPGPQCPGPPGLPAQARATHSGGETPPRISIHIQEMDT 344
Query: 553 PGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVPIPRPGPAQGDG 611
PG + + S GP+ + P + PG G P PG +G
Sbjct: 345 PGEM-----LMTGRGSLGPTLTT--EAPAAAQPGKQGPPGTGRCLQAPGTEPGEQTPEG 396
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 44.3 bits (103), Expect = 4e-04
Identities = 72/284 (25%), Positives = 102/284 (35%), Gaps = 32/284 (11%)
Query: 359 SGRAPLSP--SLNSRPSPI------SATPPALVPETR--EYRSQSPVRSMDEAPCVNGRW 408
S R PLS ++ R SP S TPP+ ++R R+ SP M +AP +
Sbjct: 2382 SPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQS--- 2438
Query: 409 GTLRPRAQRQTPSGSREGSLSPAR---GDGSPILNGGSLSPGTAAVGGSSLDSPVQAISP 465
L P AQ Q S +R +P+ SLS G A SS +S
Sbjct: 2439 --LLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSV 2496
Query: 466 STPSAPEGY----DLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNR 521
P P G +L K+ R S + +SSS+ +
Sbjct: 2497 PAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSS 2556
Query: 522 ------TVGGSMRHPPEQT-NGVHTP---PHVASALAGAVSPGALRRSLEAIKAMSSKGP 571
+ G S+ PE V +P P A P +R + + SS
Sbjct: 2557 GSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSS 2616
Query: 572 SASAALSPPLGSSPGSPGSQSLSSGETVPIPRPGPAQGDGHSLP 615
S+S++ S SS S S S SS + P PA+ +LP
Sbjct: 2617 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALP 2660
Score = 40.0 bits (92), Expect = 0.008
Identities = 68/279 (24%), Positives = 99/279 (35%), Gaps = 31/279 (11%)
Query: 367 SLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSGSREG 426
SL + P S + L + + P+ S+ AP N A R + +
Sbjct: 2189 SLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAAN--------LASRIPAASAAAM 2240
Query: 427 SLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPS--------TPSAPEGYDLKI 478
+L+ AR P + S AA +L SP A++PS TP+AP +
Sbjct: 2241 NLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPA-----V 2295
Query: 479 GLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTN--G 536
L+ A +L G+ + P+SS P VG H N G
Sbjct: 2296 NLAGARTPAALAALSLTGSGTPPTAANY-PSSSRTPQAPASANLVGPRSAHATAPVNIAG 2354
Query: 537 VHTPPHVASA--LAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPL-----GSSPGSPG 589
T +A A + ++P +L + + S S SPPL +P S
Sbjct: 2355 SRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAP 2414
Query: 590 SQSLSSGETVPIPRPGPAQGDGHSLPPIARRLGHHPPQS 628
SQS + E P P Q SL P A+ P S
Sbjct: 2415 SQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPS 2453
Score = 40.0 bits (92), Expect = 0.008
Identities = 64/263 (24%), Positives = 98/263 (37%), Gaps = 31/263 (11%)
Query: 357 APSGRAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQ 416
+PS R +PS + P P P + VP + QS P + + A
Sbjct: 2426 SPSSRMGQAPSQSLLP-PAQDQPRSPVPSA--FSDQSRCLIAQTTPVAGSQSLSSGAVAT 2482
Query: 417 RQTPSGSREGSLS-PARGD-----GSPILNGGSLSPGTAAV------GGSSLDSPVQAIS 464
+ +G G LS PA G G P + G+ P A SS S + S
Sbjct: 2483 TTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSS 2542
Query: 465 PSTPSAPEGYDLKIGLSLAPRRGS-LPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTV 523
S+ S+ G S + GS LP Q ++ L + P+ + P + +
Sbjct: 2543 SSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRV-------PSPTPAPKEAVREG-- 2593
Query: 524 GGSMRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGS 583
PPE T +S+ + + S + S + + SS S+S++ S S
Sbjct: 2594 -----RPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2648
Query: 584 -SPGSPGSQSLSSGETVPIPRPG 605
SP PG Q+L + P PG
Sbjct: 2649 PSPAKPGPQALPKPASPKKPPPG 2671
Score = 38.5 bits (88), Expect = 0.022
Identities = 77/311 (24%), Positives = 109/311 (35%), Gaps = 62/311 (19%)
Query: 363 PLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCV------NGRWGTLRPRAQ 416
P +PS S P AL P+T RS+SP C+ +G ++ +
Sbjct: 1470 PRTPSRGRSECDSSPEPKAL-PQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTV 1528
Query: 417 RQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDL 476
+TP G R S S D P S SP + SS DS + +P + G
Sbjct: 1529 ARTPLGQRSRSGSSQELDVKP-----SASPQERSESDSSPDSKAKTRTPLRQRSRSGSSP 1583
Query: 477 KIGLS--LAPRR---GSLPDQKDL-----------------------------RLGSIDL 502
++ L+PRR GS P+ KD R GS
Sbjct: 1584 EVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSK 1643
Query: 503 NWDLKPASSSN----PMDGMDNRTVGGSMRHPPEQTNGVHTPPHVASALAGAVSPGALRR 558
P SS+ P +RT R PE TPP S+ + SP R+
Sbjct: 1644 GRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRS---SPELTRK 1700
Query: 559 SLEAIKAMSSKGPSASAALSPPLG------SSPGSPGSQSLSS--GETVPIPRPGPAQGD 610
+ + ++ S+ + + +PP SSP P +S SS + PR
Sbjct: 1701 ARLSRRSRSASSSPETRSRTPPRHRRSPSVSSP-EPAEKSRSSRRRRSASSPRTKTTSRR 1759
Query: 611 GHSLPPIARRL 621
G S P R L
Sbjct: 1760 GRSPSPKPRGL 1770
Score = 33.5 bits (75), Expect = 0.70
Identities = 61/261 (23%), Positives = 91/261 (34%), Gaps = 63/261 (24%)
Query: 355 SQAPSGRAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSM-DEAPCVNGRWGTLRP 413
S P ++ P S SP A ++ P+ R SP + P + G+ P
Sbjct: 839 SPHPKVKSGTPPRQGSITSP-QANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPP 897
Query: 414 RAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEG 473
R + TP SP+R +SP + GSS SP + S +TP
Sbjct: 898 RVKSSTPPRQ-----SPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTP----- 947
Query: 474 YDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTV---GGSMRHP 530
+ + S +P +++R + S
Sbjct: 948 ---------------------------------RRSRSVSPCSNVESRLLPRYSHSGSSS 974
Query: 531 PEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSP-PLGSSPGS-- 587
P+ TPP + +G++SP +KA + GPS S + SP P S S
Sbjct: 975 PDTKVKPETPPR--QSHSGSISP------YPKVKAQTPPGPSLSGSKSPCPQEKSKDSLV 1026
Query: 588 ---PGSQSLSSGETVPIPRPG 605
PGS SL +G P PG
Sbjct: 1027 QSCPGSLSLCAGVKSSTP-PG 1046
>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
Length = 1336
Score = 43.9 bits (102), Expect = 5e-04
Identities = 44/198 (22%), Positives = 71/198 (35%), Gaps = 37/198 (18%)
Query: 418 QTPSGSR--EGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYD 475
Q P G++ +G P G P +G PG+ + G P+ ++P P G
Sbjct: 732 QGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPG-- 789
Query: 476 LKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTN 535
PR P + + +G P + GG + H P++
Sbjct: 790 --------PRENQGPAPQGMIMGH-------------PPQEMRGPHPPGGLLGHGPQEMR 828
Query: 536 GVHTPPHVASALAGAVSPGALRRSLEAIK----AMSSKGPSASAALSPPLGSSPGSPGSQ 591
G P + G G++ + ++ + S +GP + PP G G PG Q
Sbjct: 829 G----PQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQ 884
Query: 592 SLSSGETVPIPRPGPAQG 609
G+ P P P+QG
Sbjct: 885 ----GQQNPARGPHPSQG 898
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 43.1 bits (100), Expect = 9e-04
Identities = 63/288 (21%), Positives = 99/288 (34%), Gaps = 43/288 (14%)
Query: 355 SQAPSGRAPLS-------PSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGR 407
S+ P+ R P S P+ N+ P P+S+ A Q +R E G+
Sbjct: 87 SRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGK 146
Query: 408 WGTLRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPST 467
T P+ + +G+R + P G SP + S + GT L P + P
Sbjct: 147 -ATEAPKRSALS-AGARRDTSGPTPGTPSPAMARRSRAAGTEV----GLPRPAPSARPRP 200
Query: 468 PSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSM 527
P+ EG PR K + S + PA+ P + GG +
Sbjct: 201 PT--EG----------PR-------KSVSSASEHSTTEPSPAARRRP-------SAGGGL 234
Query: 528 RHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGS 587
+ P ++ P + A +G + G R S P AL PP + P
Sbjct: 235 QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP----SQPKPKGLQALRPPQVTPPRK 290
Query: 588 PGSQSLSSGETVPIPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKPL 635
+ +L + P+ P P+ PP H + + PL
Sbjct: 291 DAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPL 338
Score = 39.7 bits (91), Expect = 0.010
Identities = 60/281 (21%), Positives = 87/281 (30%), Gaps = 13/281 (4%)
Query: 355 SQAPSGRAPLSPSLNSRPSPISATPPALVPET-REYRSQSPVRSMDEAPCVNGRWGTLRP 413
++ P+ RAP L RP PP + P R + V A G G P
Sbjct: 14 ARTPAARAP--GLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71
Query: 414 RAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEG 473
+ + G+ S P G +P + SP +A + P
Sbjct: 72 ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQ 131
Query: 474 YDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQ 533
L+I RG + S D + P M R+
Sbjct: 132 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE----- 186
Query: 534 TNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSL 593
V P SA + G R+S+ + S+ PS +A P G P S+SL
Sbjct: 187 ---VGLPRPAPSARPRPPTEGP-RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242
Query: 594 SSGETVPIPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKP 634
SS T P+ P + P P+ L +P
Sbjct: 243 SSSAT-PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP 282
Score = 36.6 bits (83), Expect = 0.083
Identities = 65/250 (26%), Positives = 93/250 (37%), Gaps = 46/250 (18%)
Query: 363 PLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSG 422
P S SL+S +P+S SP RS A GT R A P
Sbjct: 237 PASRSLSSSATPLS----------------SPARSGPSAR------GTPRAPAHPSQPKP 274
Query: 423 S-----REGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTP-SAPEGYDL 476
R ++P R D +P L S SP ++L S P+TP S+ L
Sbjct: 275 KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQL 334
Query: 477 KIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNG 536
L LAP S P L ++ P+ ++ + + + PP +
Sbjct: 335 ATPLPLAPPSPSAPPS----LQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP--LSP 388
Query: 537 VHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSG 596
+ TPP A P AL +L ++A S P AS LSP SP +P + ++
Sbjct: 389 LATPPPQA--------PPAL--ALPPLQAPPS--PPASPPLSPLATPSPQAPNALAVHLL 436
Query: 597 ETVPIPRPGP 606
+ P P P
Sbjct: 437 QAPFSPPPSP 446
Score = 32.3 bits (72), Expect = 1.6
Identities = 36/161 (22%), Positives = 58/161 (36%), Gaps = 6/161 (3%)
Query: 311 DAWLLHMHSGPWAWQPLK--VENEEHGAPELW---CHPACRVGQCVVVFSQAPSGRAPLS 365
DA L H W+ P GAP W P G C + ++ P P
Sbjct: 660 DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAP 719
Query: 366 PSLNSRPSPISATPPALVPETREYRSQSPVRS-MDEAPCVNGRWGTLRPRAQRQTPSGSR 424
+L+ PSP ++ A S+SP ++ + E P + ++ R +
Sbjct: 720 GALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAA 779
Query: 425 EGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISP 465
EG+ + G GG AA+ + L + +SP
Sbjct: 780 EGAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSP 820
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 43.1 bits (100), Expect = 9e-04
Identities = 64/283 (22%), Positives = 101/283 (35%), Gaps = 43/283 (15%)
Query: 361 RAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTP 420
RAP P+ N+ P P+S+ A Q +R E G+ T P+ +
Sbjct: 93 RAP--PAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGK-ATEAPKRSALS- 148
Query: 421 SGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGL 480
+G+R + P G SP + S + GT L P + P P+ EG
Sbjct: 149 AGARRDTSGPTPGTPSPAMARRSRAAGTEV----GLPRPAPSARPRPPT--EG------- 195
Query: 481 SLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTP 540
PR K + S + PA+ P + GG ++ P ++
Sbjct: 196 ---PR-------KSVSSASEHSTTEPSPAARRRP-------SAGGGLQRPASRSLSSSAT 238
Query: 541 PHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVP 600
P + A +G + G R S P AL PP + P + +L + P
Sbjct: 239 PLSSPARSGPSARGTPRAPAHP----SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 294
Query: 601 IPRPGPAQGDGHSLPPIARRLGHHP-----PQSLNVGKPLYQS 638
+ P P+ S PP + L P + ++G P Q+
Sbjct: 295 LATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQA 337
Score = 34.3 bits (77), Expect = 0.41
Identities = 74/312 (23%), Positives = 107/312 (34%), Gaps = 63/312 (20%)
Query: 366 PSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQR----QTPS 421
P+ ++RP P + P V E+ + P + P G G RP ++ TP
Sbjct: 183 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG--GLQRPASRSLSSSATPL 240
Query: 422 GSREGSLSPARGD-------------GSPILNGGSLSP---GTAAVGGSSLDSPVQAISP 465
S S ARG G L ++P A G SP+ SP
Sbjct: 241 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 300
Query: 466 STPSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGS--IDLNWDLKPASSSNPMDGMDNRTV 523
S P +P L P + P Q LGS + P+ +P+
Sbjct: 301 SAPPSPSAPPSLQTLPSPP--ATPPSQATTSLGSPTLQATHSFLPSPPLSPL-ATPPPQA 357
Query: 524 GGSMRHPPEQT--NGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPS--------- 572
++ PP Q + +PP A +P AL ++ ++A S PS
Sbjct: 358 PPALALPPLQAPPSPPASPPLSPLATPSPQAPNAL--AVHLLQAPFSPPPSPPVQAPFSP 415
Query: 573 -ASAALS---------------PPLGSSPGSPGSQSLSSGETVPIPRPGPAQGDGHSLPP 616
AS +S PPL P P S +S T P P P + PP
Sbjct: 416 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL-----AAPP 470
Query: 617 IARRLGHHPPQS 628
+ +L PPQ+
Sbjct: 471 L--QLAKPPPQA 480
Score = 32.7 bits (73), Expect = 1.2
Identities = 62/274 (22%), Positives = 98/274 (35%), Gaps = 27/274 (9%)
Query: 355 SQAPSGRAPLSPSLNSRPSPISATP-PALVPETR----EYRSQSPVRSMDEAPCVNGRWG 409
++AP A + + P TP PA+ +R E P S P G
Sbjct: 139 TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRK 198
Query: 410 TLRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPS 469
++ ++ T S P+ G G SLS + + P +P P+
Sbjct: 199 SVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPA 258
Query: 470 APEGYDLKIGLSLAPRRGSLPDQKDLR--LGSIDLNWDLKPASSSNPMDGMDN--RTVGG 525
P K +L P + + P +KD LG + + P+ S+ P +T+
Sbjct: 259 HPSQPKPKGLQALRPPQVT-PPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPS 317
Query: 526 SMRHPPEQTNG-------------VHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPS 572
PP Q + +PP A +P AL +L ++A S P
Sbjct: 318 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL--ALPPLQAPPS--PP 373
Query: 573 ASAALSPPLGSSPGSPGSQSLSSGETVPIPRPGP 606
AS LSP SP +P + ++ + P P P
Sbjct: 374 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 407
Score = 32.3 bits (72), Expect = 1.6
Identities = 36/161 (22%), Positives = 58/161 (36%), Gaps = 6/161 (3%)
Query: 311 DAWLLHMHSGPWAWQPLK--VENEEHGAPELW---CHPACRVGQCVVVFSQAPSGRAPLS 365
DA L H W+ P GAP W P G C + ++ P P
Sbjct: 621 DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAP 680
Query: 366 PSLNSRPSPISATPPALVPETREYRSQSPVRS-MDEAPCVNGRWGTLRPRAQRQTPSGSR 424
+L+ PSP ++ A S+SP ++ + E P + ++ R +
Sbjct: 681 GALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAA 740
Query: 425 EGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISP 465
EG+ + G GG AA+ + L + +SP
Sbjct: 741 EGAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSP 781
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 42.7 bits (99), Expect = 0.001
Identities = 72/291 (24%), Positives = 97/291 (33%), Gaps = 37/291 (12%)
Query: 358 PSGRAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQR 417
PS AP PSL + PSP ATPP+ P + S+ P + P Q
Sbjct: 346 PSPSAP--PSLQTLPSP-PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQA 402
Query: 418 QTPSGSREGSLSPARGDGSPILNGG----SLSPGTAAVGGSSLDSPVQAISPSTP----- 468
PS SL GSP L ++SP +S P S P
Sbjct: 403 P-PSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPL 461
Query: 469 SAPEGYDLKIGLSLAPRRGSLP-------------------DQKDLRLGSIDLNWDLKPA 509
S P L+ LS A S P L + ++ L P
Sbjct: 462 SLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPP 521
Query: 510 SSSNPMDGMDNRTVGG--SMRHPPEQTNGVH-TPPHVASALAGAVSPGALRRSLEAIKAM 566
S P + + S+ PP QT T PH+ + A P L+ +
Sbjct: 522 SLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP--LQAPPSPLTTP 579
Query: 567 SSKGPSASAALSPPLGSSPGSPGSQSLSSGETVPIPRPGPAQGDGHSLPPI 617
+ PS+ A P + SP Q L S P+ P P +LPP+
Sbjct: 580 PPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPL 630
Score = 42.4 bits (98), Expect = 0.002
Identities = 60/269 (22%), Positives = 95/269 (35%), Gaps = 43/269 (15%)
Query: 355 SQAPSGRAPLS-------PSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGR 407
S+ P+ R P S P+ N+ P P+S+ A Q +R E G+
Sbjct: 87 SRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGK 146
Query: 408 WGTLRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPST 467
T P+ + +G+R + P G SP + S + GT L P + P
Sbjct: 147 -ATEAPKRSALS-AGARRDTSGPTPGTPSPAMARRSRAAGTEV----GLPRPAPSARPRP 200
Query: 468 PSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSM 527
P+ EG PR K + S + PA+ P + GG +
Sbjct: 201 PT--EG----------PR-------KSVSSASEHSTTEPSPAARRRP-------SAGGGL 234
Query: 528 RHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGS 587
+ P ++ P + A +G + G R S P AL PP + P
Sbjct: 235 QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP----SQPKPKGLQALRPPQVTPPRK 290
Query: 588 PGSQSLSSGETVPIPRPGPAQGDGHSLPP 616
+ +L + P+ P P+ +PP
Sbjct: 291 DAAPALGPLSSSPLATPSPSGTKARPVPP 319
Score = 39.7 bits (91), Expect = 0.010
Identities = 60/281 (21%), Positives = 87/281 (30%), Gaps = 13/281 (4%)
Query: 355 SQAPSGRAPLSPSLNSRPSPISATPPALVPET-REYRSQSPVRSMDEAPCVNGRWGTLRP 413
++ P+ RAP L RP PP + P R + V A G G P
Sbjct: 14 ARTPAARAP--GLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71
Query: 414 RAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEG 473
+ + G+ S P G +P + SP +A + P
Sbjct: 72 ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQ 131
Query: 474 YDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQ 533
L+I RG + S D + P M R+
Sbjct: 132 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE----- 186
Query: 534 TNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSL 593
V P SA + G R+S+ + S+ PS +A P G P S+SL
Sbjct: 187 ---VGLPRPAPSARPRPPTEGP-RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242
Query: 594 SSGETVPIPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKP 634
SS T P+ P + P P+ L +P
Sbjct: 243 SSSAT-PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP 282
Score = 35.0 bits (79), Expect = 0.24
Identities = 73/317 (23%), Positives = 115/317 (36%), Gaps = 31/317 (9%)
Query: 321 PWAWQPLKVENEEHGAPELWCHPACRVGQCVVVFSQAPSGRAPLSPSLNSRPSPISATPP 380
P A PL+V +P + P+ V AP + P SP + SP++ PP
Sbjct: 729 PLAAPPLQVPPSPPASPPM--SPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPP 786
Query: 381 ALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSGSREGS-LSPARGDGSPIL 439
P + P++++ P P +PS S S L+ P+L
Sbjct: 787 QAPPAL----ATPPLQALPSPP-------ASFPGQAPFSPSASLPMSPLATPPPQAPPVL 835
Query: 440 NGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGLSLAPRRGSLPDQK-DLRLG 498
L + +L +P + +P ++ G ++ L+LAP P + L
Sbjct: 836 AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG--PRLTLALAPGPPPPPSRSPSSTLS 893
Query: 499 SIDLNWDLKPASSS-NPMDGMDNRTVGGSMRHPPEQTNGVHTPPHVASALAGAVSPGALR 557
DL A+S+ + G D+ GG+ PP H A+ G P A R
Sbjct: 894 GPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAE--LAACHPAAWSRGPAPPLAFR 951
Query: 558 RSLEA-IKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVPIPRPGPAQG------- 609
+ A + + GP ++ L + P S + + G P P PG + G
Sbjct: 952 GAPGAPLPWPPATGPGSADGLCTIYETE--GPESATPAPGALDPGPSPGTSGGKAAAGAG 1009
Query: 610 -DGHSLPPIARRLGHHP 625
S P RLG P
Sbjct: 1010 AGASSRSPKQARLGELP 1026
Score = 32.3 bits (72), Expect = 1.6
Identities = 61/297 (20%), Positives = 97/297 (32%), Gaps = 60/297 (20%)
Query: 357 APSGRAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQ 416
+P + LSP+++ SP++ P + + Q+P+ S+ + P +
Sbjct: 466 SPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSL------------IMPPLE 513
Query: 417 RQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDL 476
Q+ PA P+ N SL+P + L +P TP P L
Sbjct: 514 TQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTP----HLETPPCPAPCPL 569
Query: 477 KIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNG 536
+ AP + PA +S P+ G+ + + PP+
Sbjct: 570 Q-----APPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPX 624
Query: 537 VHTPPHVAS------------ALAGAVSPGALRRSLEAIKAMSSKGPS----------AS 574
+ PP A A +P AL ++ ++A S PS AS
Sbjct: 625 LALPPLQAPPSPPASPPLSPLATPSPQAPNAL--AVHLLQAPFSPPPSPPVQAPFSPPAS 682
Query: 575 AALS---------------PPLGSSPGSPGSQSLSSGETVPIPRPGPAQGDGHSLPP 616
+S PPL P P S +S T P P P +PP
Sbjct: 683 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPP 739
Score = 32.3 bits (72), Expect = 1.6
Identities = 36/161 (22%), Positives = 58/161 (36%), Gaps = 6/161 (3%)
Query: 311 DAWLLHMHSGPWAWQPLK--VENEEHGAPELW---CHPACRVGQCVVVFSQAPSGRAPLS 365
DA L H W+ P GAP W P G C + ++ P P
Sbjct: 929 DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAP 988
Query: 366 PSLNSRPSPISATPPALVPETREYRSQSPVRS-MDEAPCVNGRWGTLRPRAQRQTPSGSR 424
+L+ PSP ++ A S+SP ++ + E P + ++ R +
Sbjct: 989 GALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAA 1048
Query: 425 EGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISP 465
EG+ + G GG AA+ + L + +SP
Sbjct: 1049 EGAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSP 1089
>gi|72004269 tetra-peptide repeat homeobox [Homo sapiens]
Length = 411
Score = 42.7 bits (99), Expect = 0.001
Identities = 64/272 (23%), Positives = 96/272 (35%), Gaps = 49/272 (18%)
Query: 361 RAPLSPSLNSRPSPI----SATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQ 416
R P +R +P+ SA+ P P ++ + S+ +A WG RAQ
Sbjct: 32 RVPGQRGRGARAAPLVPAASASAPQRGPSGILPAAEPTICSLHQA------WGGPGCRAQ 85
Query: 417 RQTPSGSREGSLSPARGDGSPILNGGSLSPGTAA-------VGGSSLDSPVQAISPSTPS 469
+ P+ +LSP G + G + PG G + + SP+ A P S
Sbjct: 86 KGIPA-----ALSPGPGPIPAPIPGPAQIPGPLPGSIPGPIPGPAQIPSPIPAPIPGPIS 140
Query: 470 APEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRH 529
P P RG +P P S P+ G + G
Sbjct: 141 GPVQIP-------GPFRGPIPG----------------PISGPAPIPGPISGPFSGPNPG 177
Query: 530 PPEQTNGVHTPPHVASALAGAVS---PGALRRSLEAIKAMSSKGPSASAALSPPLGSSPG 586
P N P ++ + G +S PG + + + + GP P G +PG
Sbjct: 178 PIPGPNPGPIPGPISGPIPGPISVPIPGPIPGPISGPISGPNPGPIPGPIPGPISGPNPG 237
Query: 587 S-PGSQSLSSGETVPIPRPGPAQGDGHSLPPI 617
PG S + +P P PGP G G + PI
Sbjct: 238 PIPGPISGPNPGLIPGPIPGPISGPGPIIGPI 269
>gi|59806361 hypothetical protein LOC387104 [Homo sapiens]
Length = 947
Score = 41.6 bits (96), Expect = 0.003
Identities = 70/279 (25%), Positives = 99/279 (35%), Gaps = 52/279 (18%)
Query: 355 SQAPSGRAPLSPSLNSRPSPISATPPALVPE---TREYRSQSPVRSMDEA---------- 401
SQ P G A +P+ + +AT L PE ++ R+QSP R D +
Sbjct: 2 SQPPIGGA--APATAAASPAAAATEARLHPEGSSRKQQRAQSPARPRDSSLRQTIAATRS 59
Query: 402 PCVNG------RWGTLRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSS 455
P G R L+ + Q+ +GSR G + RG G L+P AA G
Sbjct: 60 PVGAGTKLNSVRQQQLQQQQQQGNKTGSRTGPPASIRGGGGGAEKATPLAPKGAAPGAVQ 119
Query: 456 LDSPVQAISPSTPSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPM 515
+ +A +T +A L RR P++ L S+ P
Sbjct: 120 PVAGAEAAPAATLAA-----------LGGRRPGPPEEPPRELESVPSKLGEPPPLGEGGG 168
Query: 516 DGMDNRTVGGSMRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASA 575
G + GG E+ G PP P R + ++A G
Sbjct: 169 GGGEGGGAGGG---SGEREGGAPQPP----------PPRGWRG--KGVRAQQRGGSGGEG 213
Query: 576 ALSPPLGSSPG-SPGSQSLSSGETVPIPRPGPAQGDGHS 613
A P SS G +PG+ S +SG V G G G S
Sbjct: 214 ASPSPSSSSAGKTPGTGSRNSGSGV----AGGGSGGGGS 248
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 41.6 bits (96), Expect = 0.003
Identities = 70/296 (23%), Positives = 106/296 (35%), Gaps = 49/296 (16%)
Query: 357 APSGRAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQ 416
+P+ + PL P+ S P PP P++ S S GT+
Sbjct: 520 SPAFQPPLPPTDGSTVVPAGPEPP---PQSSRAESSSG-------------GGTV----- 558
Query: 417 RQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEG-YD 475
PS + P+ GDGSP P +AAV ++ A + P A G +
Sbjct: 559 ---PSSAGILEQGPSPGDGSP---PKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQ 612
Query: 476 LKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPE--- 532
L +G P + P LR ++ P + P ++ G+ +HPP
Sbjct: 613 LSMG---QPHNAAGPSPHTLRR-AVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSP 668
Query: 533 ---------QTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGS 583
T PP SA + +P SL I+A + P +P + +
Sbjct: 669 KPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHT 728
Query: 584 SP---GSPGSQSLSSGETVPIPRPGPAQ-GDGHSLPPIARRLGHHP-PQSLNVGKP 634
P G P +L S + P P Q S PP+ ++ P PQ+L G P
Sbjct: 729 KPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNP 784
Score = 41.6 bits (96), Expect = 0.003
Identities = 59/226 (26%), Positives = 86/226 (38%), Gaps = 45/226 (19%)
Query: 410 TLRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPS 469
TLR ++ P+ + G+ P G P GG S GT+ S P SPS P+
Sbjct: 628 TLRRAVKKPAPAPPKPGNPPP----GHP---GGQSSSGTSQHPPSLSPKPPTR-SPSPPT 679
Query: 470 APEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRH 529
G P + S P Q L+ + +SS +P+ + H
Sbjct: 680 QHTGQP--------PGQPSAPSQ---------LSAPRRYSSSLSPIQAPN---------H 713
Query: 530 PPEQTNGVHTP-PHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGS-SPGS 587
PP Q TP H G +P AL + + + + +PPLG +P
Sbjct: 714 PPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSL 773
Query: 588 PGSQSLSSGE---------TVPIPRPGPAQGDGHSLPPIARRLGHH 624
P Q+L+ G T+P PRP P + S+PP + G H
Sbjct: 774 PAPQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQPPGVH 819
>gi|54860105 nadrin isoform 2 [Homo sapiens]
Length = 803
Score = 41.6 bits (96), Expect = 0.003
Identities = 59/226 (26%), Positives = 86/226 (38%), Gaps = 45/226 (19%)
Query: 410 TLRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPS 469
TLR ++ P+ + G+ P G P GG S GT+ S P SPS P+
Sbjct: 550 TLRRAVKKPAPAPPKPGNPPP----GHP---GGQSSSGTSQHPPSLSPKPPTR-SPSPPT 601
Query: 470 APEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRH 529
G P + S P Q L+ + +SS +P+ + H
Sbjct: 602 QHTGQP--------PGQPSAPSQ---------LSAPRRYSSSLSPIQAPN---------H 635
Query: 530 PPEQTNGVHTP-PHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGS-SPGS 587
PP Q TP H G +P AL + + + + +PPLG +P
Sbjct: 636 PPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSL 695
Query: 588 PGSQSLSSGE---------TVPIPRPGPAQGDGHSLPPIARRLGHH 624
P Q+L+ G T+P PRP P + S+PP + G H
Sbjct: 696 PAPQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQPPGVH 741
Score = 35.0 bits (79), Expect = 0.24
Identities = 55/243 (22%), Positives = 87/243 (35%), Gaps = 31/243 (12%)
Query: 419 TPSGSREGSLSPARGDGSPILNGGSLS---------PGTAAVGGSSLDSPVQAISPSTPS 469
T + S G+L R ++ G + P +AAV ++ A + P
Sbjct: 468 TGNDSDSGTLERKRPASMAVMEGDLVKKESPPKPKDPVSAAVPAPGRNNSQIASGQNQPQ 527
Query: 470 APEG-YDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMR 528
A G + L +G P + P LR ++ P + P ++ G+ +
Sbjct: 528 AAAGSHQLSMG---QPHNAAGPSPHTLRR-AVKKPAPAPPKPGNPPPGHPGGQSSSGTSQ 583
Query: 529 HPPE------------QTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAA 576
HPP T PP SA + +P SL I+A + P
Sbjct: 584 HPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQ 643
Query: 577 LSPPLGSSP---GSPGSQSLSSGETVPIPRPGPAQ-GDGHSLPPIARRLGHHP-PQSLNV 631
+P + + P G P +L S + P P Q S PP+ ++ P PQ+L
Sbjct: 644 ATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAG 703
Query: 632 GKP 634
G P
Sbjct: 704 GNP 706
>gi|72256200 B-cell CLL/lymphoma 9 [Homo sapiens]
Length = 1426
Score = 41.6 bits (96), Expect = 0.003
Identities = 58/253 (22%), Positives = 98/253 (38%), Gaps = 14/253 (5%)
Query: 363 PLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQ---T 419
PL+PS N P+ ++ PP R+ S S +P +N + Q +
Sbjct: 821 PLNPSSN--PTSLNTAPPVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGS 878
Query: 420 PSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIG 479
PSG+ + +P++ G + S + V GS+ SPV SPS P+ G+
Sbjct: 879 PSGNLKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTSSPK 938
Query: 480 LSLAP------RRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRH--PP 531
L + L LG+++ + P ++S P ++ S + PP
Sbjct: 939 PPLQSPGIPPNHKAPLTMASPAMLGNVE-SGGPPPPTASQPASVNIPGSLPSSTPYTMPP 997
Query: 532 EQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQ 591
E T + + S ++ P + +AIK ++S + A SP L S PG
Sbjct: 998 EPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMG 1057
Query: 592 SLSSGETVPIPRP 604
+ + P P
Sbjct: 1058 INTQNPRISGPNP 1070
Score = 33.1 bits (74), Expect = 0.92
Identities = 38/131 (29%), Positives = 47/131 (35%), Gaps = 22/131 (16%)
Query: 505 DLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAI- 563
D KP P ++ + R P TPP A A A P L R +
Sbjct: 230 DPKPLPQQPPAPANQDQNSSQNTRLQP-------TPPIPAPAPKPAAPPRPLDRESPGVE 282
Query: 564 -KAMSSKGPSASAALSPPLGSSPGS--------PGSQSLSSGETVPIPRPGPAQGDGHSL 614
K + S G AS+ PP G+ P S P SQ +S P P P G
Sbjct: 283 NKLIPSVGSPASSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGE-- 340
Query: 615 PPIARRLGHHP 625
PP LG +P
Sbjct: 341 PP---TLGENP 348
Score = 31.6 bits (70), Expect = 2.7
Identities = 90/361 (24%), Positives = 132/361 (36%), Gaps = 63/361 (17%)
Query: 363 PLSPSLNSRPSPISA---TPPALVPETREYRSQSPV--RSMDEAPCV-NGRWGTLRPRAQ 416
PLS S N PSP + PP VP S +P+ E P V GR G +
Sbjct: 1085 PLSHS-NQMPSPNAVGPNIPPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPP 1143
Query: 417 RQTPSGSREGSLS-PARGDGSPILNGGSLSPGTAAVGGSS----LDSPVQAISPSTPSAP 471
Q+P + P+ G GS GG PG +G S + P P P
Sbjct: 1144 VQSPPQQVPFPHNGPSGGQGS--FPGGMGFPGEGPLGRPSNLPQSSADAALCKPGGPGGP 1201
Query: 472 EGYDLKIGLSLAPRRGSLPD-QKDLRLGS-----IDLNWDLKPASSSNPMDGMDNRTVGG 525
+ + + +G S+ P + PD Q+ +R G+ DL+ + S + V G
Sbjct: 1202 DSFTV-LGNSM-PSVFTDPDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPG 1259
Query: 526 SMRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSP 585
+Q G P S + G + A R L A+ M GP + + PLG++P
Sbjct: 1260 R-----KQPQG---PGPGFSHMQGMMGEQAPRMGL-ALPGMGGPGPVGTPDI--PLGTAP 1308
Query: 586 GSPGSQSLSSGETVPIPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKPLYQSMNCKPMQ 645
PG P PA + P R + P QS G+P S +
Sbjct: 1309 SMPGHN----------PMRPPAFLQQGMMGPHHRMMS--PAQSTMPGQPTLMSNPAAAVG 1356
Query: 646 MYVLDIKDTKEKGRVKWKVFNSSSVVGPPETSLHTVVQGRGELIIFGGLMDKKQNVKYYP 705
M + KD G ++ VG P G ++ G+M +QN+ P
Sbjct: 1357 M--IPGKDRGPAG-----LYTHPGPVGSP-----------GMMMSMQGMMGPQQNIMIPP 1398
Query: 706 K 706
+
Sbjct: 1399 Q 1399
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 41.6 bits (96), Expect = 0.003
Identities = 77/280 (27%), Positives = 97/280 (34%), Gaps = 43/280 (15%)
Query: 365 SPSLNSRPSPISATPPALVPETREYRSQSPV-----RSMDEAPCVNGRWGTLRPRAQRQT 419
SPS ++ PSP P R RS SP RS AP R T P +R+T
Sbjct: 524 SPSRSASPSPRKRQKETS-PRGRRRRSPSPPPTRRRRSPSPAPPPRRR-RTPTPPPRRRT 581
Query: 420 PSGS-REGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTP---------- 468
PS R S SP R PI S SP S P + SPS P
Sbjct: 582 PSPPPRRRSPSPRRYS-PPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPP 640
Query: 469 ----SAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPA-------SSSNPMDG 517
S+P LS R+GS P + S N P+ +SS+P
Sbjct: 641 PKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPV 700
Query: 518 MDNRTVGGSMRHPPEQTNGV-----HTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPS 572
+ R P + TP A + SP ++RR + S G
Sbjct: 701 RRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR---VSSSRSVSGSP 757
Query: 573 ASAALSPPLGSSPGSPGSQSLSSGETVPI-----PRPGPA 607
AA PP SP S S + VP+ P P P+
Sbjct: 758 EPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPS 797
Score = 39.7 bits (91), Expect = 0.010
Identities = 65/270 (24%), Positives = 89/270 (32%), Gaps = 63/270 (23%)
Query: 366 PSLNSRPSPISATPP-ALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSGSR 424
PS RPSP TPP + P R RS+SPVR + +L + + S SR
Sbjct: 315 PSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSS------ASLSGSSSSSSSSRSR 368
Query: 425 EGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGLSLAP 484
P + SP LSP S P + PS P+ P
Sbjct: 369 SPPKKPPKRTSSPPRKTRRLSP--------SASPPRRRHRPSPPATP------------- 407
Query: 485 RRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTPPHVA 544
P + +P NRT + P +T+G T H
Sbjct: 408 ----------------------PPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVT-KHKG 444
Query: 545 SALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPP------LGSSPGSPGSQSLSSGET 598
+ + SP R +E ++ KG +AA S + S S S SS E
Sbjct: 445 TEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSED 504
Query: 599 VPIPRPGPAQGDGHSLPPIARRLGHHPPQS 628
R G+ + RR H P +S
Sbjct: 505 ERPKRSHVKNGE------VGRRRRHSPSRS 528
Score = 32.7 bits (73), Expect = 1.2
Identities = 36/121 (29%), Positives = 47/121 (38%), Gaps = 7/121 (5%)
Query: 355 SQAPSGRAPLSPSLNSR--PSPISATPP--ALVPETREYRSQSPVRSMDEAPCVNGRWGT 410
S + S R SP N R PSP P + P R S SP R +P
Sbjct: 665 SPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRV 724
Query: 411 LRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSA 470
R ++ + S R S ++G SP AA + SPVQ+ SPST +
Sbjct: 725 SRTPEPKKIKKAASPSPQSVRRVSSSRSVSG---SPEPAAKKPPAPPSPVQSQSPSTNWS 781
Query: 471 P 471
P
Sbjct: 782 P 782
>gi|158508542 kelch-like 33 [Homo sapiens]
Length = 453
Score = 41.2 bits (95), Expect = 0.003
Identities = 50/221 (22%), Positives = 82/221 (37%), Gaps = 33/221 (14%)
Query: 86 AHQCYHGFMKAVQEGNIQWESRTYPYPGTPITQRFSHSACYYDANQSMYVFGGCTQSSCN 145
A +C G ++ V+ G + P P RF H A A +YV GG S +
Sbjct: 157 AFRCGVGLVRTVEWGQL---------PALPAPGRFRHGAASL-AGSELYVCGGQDFYSHS 206
Query: 146 AAFNDLWRLDLNSKEW--IRPLASGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQP 203
R + + ++W + PL+ ++ +LV L GG
Sbjct: 207 NTLASTLRWEPSQEDWEEMAPLSQA-----RSLFSLVALDGKLYALGG---------RHN 252
Query: 204 ERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVL 263
+ D + TY+P N W P P H++ +++ ++ V GG G+ Q +
Sbjct: 253 DVALDSVETYNPELNVWRPAPAL--PAPCFAHAAAILEGQLYVSGGCGGTGQYLASLMHY 310
Query: 264 DLEQWAWSKP-NISGPSPHPRGGQSQIVIDDATILILGGCG 303
D + KP P PR G + + + GG G
Sbjct: 311 DPK---LEKPGTFLSPMGVPRAGHVMAAL-GGRLYVAGGLG 347
Score = 38.9 bits (89), Expect = 0.017
Identities = 30/108 (27%), Positives = 48/108 (44%), Gaps = 15/108 (13%)
Query: 133 MYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLFGGW 192
+YV GG ++ +F + + L +S + PL PSP GA V + L++ GG+
Sbjct: 340 LYVAGGLGETEDLLSF-EAYELRTDSWTHLAPL-----PSPHVGAASAVLQGELLVLGGY 393
Query: 193 TRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVI 240
+ H+ IH Y P W C+ T P P A +C++
Sbjct: 394 S-------HRTYALSHLIHAYCPGLGRWLCLGTL--PRPRAEMPACIL 432
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.416
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,832,405
Number of Sequences: 37866
Number of extensions: 2100080
Number of successful extensions: 9164
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 63
Number of HSP's successfully gapped in prelim test: 497
Number of HSP's that attempted gapping in prelim test: 7940
Number of HSP's gapped (non-prelim): 1560
length of query: 717
length of database: 18,247,518
effective HSP length: 110
effective length of query: 607
effective length of database: 14,082,258
effective search space: 8547930606
effective search space used: 8547930606
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.