Guide to the Human Genome
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Search of human proteins with 62955044

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|62955044 F-box protein 42 [Homo sapiens]
         (717 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|62955044 F-box protein 42 [Homo sapiens]                          1494   0.0  
gi|26190616 kelch domain containing 1 [Homo sapiens]                   77   6e-14
gi|98986457 host cell factor 1 [Homo sapiens]                          75   3e-13
gi|7657301 kelch domain containing 2 [Homo sapiens]                    72   2e-12
gi|7019405 host cell factor C2 [Homo sapiens]                          70   7e-12
gi|16945972 kelch domain containing 3 [Homo sapiens]                   67   4e-11
gi|21314675 kelch domain containing 4 [Homo sapiens]                   65   2e-10
gi|47717139 leucine-zipper-like transcription regulator 1 [Homo ...    63   1e-09
gi|195963410 MEF2 activating motif and SAP domain containing tra...    58   3e-08
gi|145701025 multiple EGF-like-domains 8 [Homo sapiens]                56   1e-07
gi|33695109 Rab9 effector protein with kelch motifs [Homo sapiens]     55   2e-07
gi|44917619 kelch domain containing 10 [Homo sapiens]                  54   4e-07
gi|20143482 melanoma antigen family E, 1 [Homo sapiens]                50   6e-06
gi|46410931 attractin-like 1 [Homo sapiens]                            50   7e-06
gi|163965366 nascent polypeptide-associated complex alpha subuni...    50   9e-06
gi|21450863 attractin isoform 2 [Homo sapiens]                         48   4e-05
gi|21450861 attractin isoform 1 [Homo sapiens]                         48   4e-05
gi|146219832 myosin light chain kinase 3 [Homo sapiens]                45   2e-04
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        44   4e-04
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]               44   5e-04
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    43   9e-04
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    43   9e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    43   0.001
gi|72004269 tetra-peptide repeat homeobox [Homo sapiens]               43   0.001
gi|59806361 hypothetical protein LOC387104 [Homo sapiens]              42   0.003
gi|54860079 nadrin isoform 1 [Homo sapiens]                            42   0.003
gi|54860105 nadrin isoform 2 [Homo sapiens]                            42   0.003
gi|72256200 B-cell CLL/lymphoma 9 [Homo sapiens]                       42   0.003
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         42   0.003
gi|158508542 kelch-like 33 [Homo sapiens]                              41   0.003

>gi|62955044 F-box protein 42 [Homo sapiens]
          Length = 717

 Score = 1494 bits (3868), Expect = 0.0
 Identities = 717/717 (100%), Positives = 717/717 (100%)

Query: 1   MASSSDSEDDSFMAVDQEETVLEGTMDQDEEPHPVLEAEETRHNRSMSELPEEVLEYILS 60
           MASSSDSEDDSFMAVDQEETVLEGTMDQDEEPHPVLEAEETRHNRSMSELPEEVLEYILS
Sbjct: 1   MASSSDSEDDSFMAVDQEETVLEGTMDQDEEPHPVLEAEETRHNRSMSELPEEVLEYILS 60

Query: 61  FLSPYQEHKTAALVCKQWYRLIKGVAHQCYHGFMKAVQEGNIQWESRTYPYPGTPITQRF 120
           FLSPYQEHKTAALVCKQWYRLIKGVAHQCYHGFMKAVQEGNIQWESRTYPYPGTPITQRF
Sbjct: 61  FLSPYQEHKTAALVCKQWYRLIKGVAHQCYHGFMKAVQEGNIQWESRTYPYPGTPITQRF 120

Query: 121 SHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLV 180
           SHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLV
Sbjct: 121 SHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLV 180

Query: 181 VYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVI 240
           VYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVI
Sbjct: 181 VYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVI 240

Query: 241 DDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDATILILG 300
           DDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDATILILG
Sbjct: 241 DDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDATILILG 300

Query: 301 GCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELWCHPACRVGQCVVVFSQAPSG 360
           GCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELWCHPACRVGQCVVVFSQAPSG
Sbjct: 301 GCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELWCHPACRVGQCVVVFSQAPSG 360

Query: 361 RAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTP 420
           RAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTP
Sbjct: 361 RAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTP 420

Query: 421 SGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGL 480
           SGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGL
Sbjct: 421 SGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGL 480

Query: 481 SLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTP 540
           SLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTP
Sbjct: 481 SLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTP 540

Query: 541 PHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVP 600
           PHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVP
Sbjct: 541 PHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVP 600

Query: 601 IPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKPLYQSMNCKPMQMYVLDIKDTKEKGRV 660
           IPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKPLYQSMNCKPMQMYVLDIKDTKEKGRV
Sbjct: 601 IPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKPLYQSMNCKPMQMYVLDIKDTKEKGRV 660

Query: 661 KWKVFNSSSVVGPPETSLHTVVQGRGELIIFGGLMDKKQNVKYYPKTNALYFVRAKR 717
           KWKVFNSSSVVGPPETSLHTVVQGRGELIIFGGLMDKKQNVKYYPKTNALYFVRAKR
Sbjct: 661 KWKVFNSSSVVGPPETSLHTVVQGRGELIIFGGLMDKKQNVKYYPKTNALYFVRAKR 717


>gi|26190616 kelch domain containing 1 [Homo sapiens]
          Length = 406

 Score = 77.0 bits (188), Expect = 6e-14
 Identities = 68/252 (26%), Positives = 117/252 (46%), Gaps = 33/252 (13%)

Query: 115 PITQRFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKE----WIRPLA-SGS 169
           P +   S  AC    N  +Y+FGG      +   N L+ ++L +++    W +     G 
Sbjct: 66  PASMSGSCGACI---NGKLYIFGGYDDKGYS---NRLYFVNLRTRDETYIWEKITDFEGQ 119

Query: 170 YPSPKAGATLVVYKDLLVLFGGW--TRPSP----YPLHQP---ERFF----DEIHTY-SP 215
            P+P+   +  VYKD L+ FGG+   R S     + +H     E+ F    +++H + + 
Sbjct: 120 PPTPRDKLSCWVYKDRLIYFGGYGCRRHSELQDCFDVHDASWEEQIFWGWHNDVHIFDTK 179

Query: 216 SKNWWNCIVTTHGPP-PMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWS-KP 273
           ++ W+   +    PP P A H+  V+ +K  +FGG +   +M ND+  L+L+ W WS + 
Sbjct: 180 TQTWFQPEIKGGVPPQPRAAHTCAVLGNKGYIFGGRVLQTRM-NDLHYLNLDTWTWSGRI 238

Query: 274 NISGPSPHPRGGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVENEE 333
            I+G SP  R   +   I D  + + GG    N    D W+ ++ +  W     ++ +  
Sbjct: 239 TINGESPKHRSWHTLTPIADDKLFLCGGLSADNIPLSDGWIHNVTTNCWK----QLTHLP 294

Query: 334 HGAPELWCHPAC 345
              P LW H AC
Sbjct: 295 KTRPRLW-HTAC 305



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 53/235 (22%), Positives = 84/235 (35%), Gaps = 36/235 (15%)

Query: 133 MYVFGGCTQSSCNAAF---NDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLF 189
           +YV+GG      N  +   +++W  D++S  W   L  G  P+  +G+        L +F
Sbjct: 25  LYVWGGYVSIEDNEVYLPNDEIWTYDIDSGLWRMHLMEGELPASMSGSCGACINGKLYIF 84

Query: 190 GGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSC-VIDDKMIVFG 248
           GG+        +    +F  + T   +  W         PP      SC V  D++I FG
Sbjct: 85  GGYDDKG----YSNRLYFVNLRTRDETYIWEKITDFEGQPPTPRDKLSCWVYKDRLIYFG 140

Query: 249 GSLGSRQMS----------------------NDVWVLDLEQWAWSKPNI-SGPSPHPRGG 285
           G  G R+ S                      NDV + D +   W +P I  G  P PR  
Sbjct: 141 G-YGCRRHSELQDCFDVHDASWEEQIFWGWHNDVHIFDTKTQTWFQPEIKGGVPPQPRAA 199

Query: 286 QSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELW 340
            +  V+ +   +     GG     +   L +++   W W      N E      W
Sbjct: 200 HTCAVLGNKGYIF----GGRVLQTRMNDLHYLNLDTWTWSGRITINGESPKHRSW 250


>gi|98986457 host cell factor 1 [Homo sapiens]
          Length = 2035

 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 66/253 (26%), Positives = 106/253 (41%), Gaps = 45/253 (17%)

Query: 133 MYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLA----SGSYPSPKAGATLVVYKDLLVL 188
           + VFGG  +    +  NDL+ L  +  EW R  A    +G  P P+ G +  +  +   L
Sbjct: 94  LLVFGGMVEYGKYS--NDLYELQASRWEWKRLKAKTPKNGPPPCPRLGHSFSLVGNKCYL 151

Query: 189 FGGWTRPSPYPLHQPERFFDEIHTYS--PSKNW--WNCIVTTHG--PPPMAGHSSCVIDD 242
           FGG    S  P +   R+ ++++     P      W+ I  T+G  PPP   H++ V  +
Sbjct: 152 FGGLANDSEDPKNNIPRYLNDLYILELRPGSGVVAWD-IPITYGVLPPPRESHTAVVYTE 210

Query: 243 K------MIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDATI 296
           K      ++++GG  G R    D+W LD++   W+KP++SG +P PR   S   I +   
Sbjct: 211 KDNKKSKLVIYGGMSGCRL--GDLWTLDIDTLTWNKPSLSGVAPLPRSLHSATTIGNKMY 268

Query: 297 LILGGCGGPNALFKDAWLLHMHSGPW--------------AWQPLKVENEEHGAPELWCH 342
           +     GG   L  D   +  H   W              AW+ + ++  E   P     
Sbjct: 269 VF----GGWVPLVMDDVKVATHEKEWKCTNTLACLNLDTMAWETILMDTLEDNIPR---- 320

Query: 343 PACRVGQCVVVFS 355
              R G C V  +
Sbjct: 321 --ARAGHCAVAIN 331



 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 44/140 (31%), Positives = 65/140 (46%), Gaps = 17/140 (12%)

Query: 167 SGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTT 226
           SG  P P+ G   V  K+L+V+FGG            E   DE+H Y+ + N W  I   
Sbjct: 26  SGPVPRPRHGHRAVAIKELIVVFGGGN----------EGIVDELHVYNTATNQW-FIPAV 74

Query: 227 HG--PPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAW----SKPNISGPSP 280
            G  PP  A +       +++VFGG +   + SND++ L   +W W    +K   +GP P
Sbjct: 75  RGDIPPGCAAYGFVCDGTRLLVFGGMVEYGKYSNDLYELQASRWEWKRLKAKTPKNGPPP 134

Query: 281 HPRGGQSQIVIDDATILILG 300
            PR G S  ++ +   L  G
Sbjct: 135 CPRLGHSFSLVGNKCYLFGG 154



 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 44/178 (24%), Positives = 74/178 (41%), Gaps = 43/178 (24%)

Query: 119 RFSHSACYY----DANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPK 174
           R SH+A  Y    +    + ++GG   S C     DLW LD+++  W +P  SG  P P+
Sbjct: 200 RESHTAVVYTEKDNKKSKLVIYGG--MSGCR--LGDLWTLDIDTLTWNKPSLSGVAPLPR 255

Query: 175 AGATLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNW--------------- 219
           +  +     + + +FGGW      PL       D++   +  K W               
Sbjct: 256 SLHSATTIGNKMYVFGGWV-----PL-----VMDDVKVATHEKEWKCTNTLACLNLDTMA 305

Query: 220 WNCI----VTTHGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSN------DVWVLDLEQ 267
           W  I    +  + P   AGH +  I+ ++ ++ G  G R+  N      D+W L+ E+
Sbjct: 306 WETILMDTLEDNIPRARAGHCAVAINTRLYIWSGRDGYRKAWNNQVCCKDLWYLETEK 363



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 49/210 (23%), Positives = 81/210 (38%), Gaps = 36/210 (17%)

Query: 135 VFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLFGGWTR 194
           VFGG  +       ++L   +  + +W  P   G  P   A    V     L++FGG   
Sbjct: 47  VFGGGNEG----IVDELHVYNTATNQWFIPAVRGDIPPGCAAYGFVCDGTRLLVFGGMVE 102

Query: 195 PSPYPLHQPERFFDEIHTYSPSKNWWNCI---VTTHGPP--PMAGHSSCVIDDKMIVFGG 249
              Y         ++++    S+  W  +      +GPP  P  GHS  ++ +K  +FGG
Sbjct: 103 YGKYS--------NDLYELQASRWEWKRLKAKTPKNGPPPCPRLGHSFSLVGNKCYLFGG 154

Query: 250 SLGSRQ--------MSNDVWVLDLEQW----AWSKPNISGPSPHPRGGQSQIVIDD---- 293
                +          ND+++L+L       AW  P   G  P PR   + +V  +    
Sbjct: 155 LANDSEDPKNNIPRYLNDLYILELRPGSGVVAWDIPITYGVLPPPRESHTAVVYTEKDNK 214

Query: 294 -ATILILGGCGGPNALFKDAWLLHMHSGPW 322
            + ++I GG  G      D W L + +  W
Sbjct: 215 KSKLVIYGGMSG--CRLGDLWTLDIDTLTW 242


>gi|7657301 kelch domain containing 2 [Homo sapiens]
          Length = 406

 Score = 71.6 bits (174), Expect = 2e-12
 Identities = 60/241 (24%), Positives = 93/241 (38%), Gaps = 28/241 (11%)

Query: 124 ACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKE----WIRPLASGSYPSPKAGATL 179
           +C    ++ +Y+FGG          N  + LD  S +    W R    G  PS K    +
Sbjct: 94  SCAVCVDRVLYLFGG---HHSRGNTNKFYMLDSRSTDRVLQWERIDCQGIPPSSKDKLGV 150

Query: 180 VVYKDLLVLFGGW--------------TRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVT 225
            VYK+ L+ FGG+                 S +    P  + D +H        W+  +T
Sbjct: 151 WVYKNKLIFFGGYGYLPEDKVLGTFEFDETSFWNSSHPRGWNDHVHILDTETFTWSQPIT 210

Query: 226 T-HGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRG 284
           T   P P A H+   + ++  VFGG     +M ND+  L+L+ W W++    G  P  R 
Sbjct: 211 TGKAPSPRAAHACATVGNRGFVFGGRYRDARM-NDLHYLNLDTWEWNELIPQGICPVGRS 269

Query: 285 GQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELWCHPA 344
             S   +    + + GG         DAW   +    W    ++  +     P LW H A
Sbjct: 270 WHSLTPVSSDHLFLFGGFTTDKQPLSDAWTYCISKNEW----IQFNHPYTEKPRLW-HTA 324

Query: 345 C 345
           C
Sbjct: 325 C 325



 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 49/150 (32%), Positives = 72/150 (48%), Gaps = 18/150 (12%)

Query: 105 ESRTYPYP---GTPITQRFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEW 161
           E+ T+  P   G   + R +H AC    N+  +VFGG  +   +A  NDL  L+L++ EW
Sbjct: 201 ETFTWSQPITTGKAPSPRAAH-ACATVGNRG-FVFGGRYR---DARMNDLHYLNLDTWEW 255

Query: 162 IRPLASGSYPSPKAGATLV-VYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWW 220
              +  G  P  ++  +L  V  D L LFGG+T        QP     +  TY  SKN W
Sbjct: 256 NELIPQGICPVGRSWHSLTPVSSDHLFLFGGFTTDK-----QP---LSDAWTYCISKNEW 307

Query: 221 NCIVTTHGPPPMAGHSSCVIDD-KMIVFGG 249
                 +   P   H++C  D+ ++IVFGG
Sbjct: 308 IQFNHPYTEKPRLWHTACASDEGEVIVFGG 337



 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 48/227 (21%), Positives = 82/227 (36%), Gaps = 44/227 (19%)

Query: 133 MYVFGGCTQSSCNAAFN------DLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLL 186
           M+V+GG   +     ++      +LW  ++ +  W +    G  P   +G+  V    +L
Sbjct: 44  MFVWGGYKSNQVRGLYDFYLPREELWIYNMETGRWKKINTEGDVPPSMSGSCAVCVDRVL 103

Query: 187 VLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSC-VIDDKMI 245
            LFGG      +      +F+      +     W  I     PP         V  +K+I
Sbjct: 104 YLFGGH-----HSRGNTNKFYMLDSRSTDRVLQWERIDCQGIPPSSKDKLGVWVYKNKLI 158

Query: 246 VFGG----------------------SLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPR 283
            FGG                      S   R  ++ V +LD E + WS+P  +G +P PR
Sbjct: 159 FFGGYGYLPEDKVLGTFEFDETSFWNSSHPRGWNDHVHILDTETFTWSQPITTGKAPSPR 218

Query: 284 GGQSQIVIDDATILILGGCGGPNALFKDAWLLHMH---SGPWAWQPL 327
              +   + +    + GG       ++DA +  +H      W W  L
Sbjct: 219 AAHACATVGNRG-FVFGG------RYRDARMNDLHYLNLDTWEWNEL 258


>gi|7019405 host cell factor C2 [Homo sapiens]
          Length = 792

 Score = 70.1 bits (170), Expect = 7e-12
 Identities = 52/179 (29%), Positives = 76/179 (42%), Gaps = 30/179 (16%)

Query: 113 GTPITQRFSHSACYYDANQS----MYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASG 168
           G   + R SH+A  Y    S    MYVFGG     C A  +DLW+LDL +  W +P   G
Sbjct: 184 GVVPSPRESHTAVIYCKKDSGSPKMYVFGGM----CGARLDDLWQLDLETMSWSKPETKG 239

Query: 169 SYPSPKAGATLVVYKDLLVLFGGW-------TRPSPYPLHQPERFFDEIHTYSPSKNWWN 221
           + P P++  T  V  + + +FGGW       T  SP+      R        +     W 
Sbjct: 240 TVPLPRSLHTASVIGNKMYIFGGWVPHKGENTETSPHDCEW--RCTSSFSYLNLDTTEWT 297

Query: 222 CIVT-------THGPPPMAGHSSCVIDDKMIVFGG------SLGSRQMSNDVWVLDLEQ 267
            +V+          P P AGH +  I  ++  + G      +L S+    D+W LD E+
Sbjct: 298 TLVSDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSGRDGYKKALNSQVCCKDLWYLDTEK 356



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 54/182 (29%), Positives = 81/182 (44%), Gaps = 20/182 (10%)

Query: 135 VFGGCTQSSCNAAFNDLWRLDLNSKEWIR----PLASGSYPSPKAGATLVVYKDLLVLFG 190
           VFGG  +    +  N+L+ L  +   W +    P  SG  P P+ G +  +Y +   LFG
Sbjct: 86  VFGGMVEYGRYS--NELYELQASRWLWKKVKPHPPPSGLPPCPRLGHSFSLYGNKCYLFG 143

Query: 191 GWTRPSPYPLHQPERFFDEIHT----YSPSKNWWNCIVTTHG-PPPMAGHSSCVI----- 240
           G    S    +   R+ ++ +     +      W+  VT    P P   H++ +      
Sbjct: 144 GLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGVVPSPRESHTAVIYCKKDS 203

Query: 241 -DDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDATILIL 299
              KM VFGG  G+R   +D+W LDLE  +WSKP   G  P PR   +  VI +  + I 
Sbjct: 204 GSPKMYVFGGMCGARL--DDLWQLDLETMSWSKPETKGTVPLPRSLHTASVIGN-KMYIF 260

Query: 300 GG 301
           GG
Sbjct: 261 GG 262



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 38/126 (30%), Positives = 58/126 (46%), Gaps = 15/126 (11%)

Query: 167 SGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKN-WWNCIVT 225
           +G  P  + G   V  ++L+++FGG            E   DE+H Y+ + N W+   V 
Sbjct: 16  TGPVPRARHGHRAVAIRELMIIFGGGN----------EGIADELHVYNTATNQWFLPAVR 65

Query: 226 THGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSK----PNISGPSPH 281
              PP  A H       +++VFGG +   + SN+++ L   +W W K    P  SG  P 
Sbjct: 66  GDIPPGCAAHGFVCDGTRILVFGGMVEYGRYSNELYELQASRWLWKKVKPHPPPSGLPPC 125

Query: 282 PRGGQS 287
           PR G S
Sbjct: 126 PRLGHS 131



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 34/126 (26%), Positives = 54/126 (42%), Gaps = 7/126 (5%)

Query: 214 SPSKNWWNCIVTTHGPPPMA--GHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWS 271
           +PS   W  + +  GP P A  GH +  I + MI+FGG  G+  +++++ V +     W 
Sbjct: 3   APSLLNWRRVSSFTGPVPRARHGHRAVAIRELMIIFGG--GNEGIADELHVYNTATNQWF 60

Query: 272 KPNISGPSPHPRGGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVEN 331
            P + G  P P       V D   IL+ GG         +  L  + +  W W+ +K   
Sbjct: 61  LPAVRGDIP-PGCAAHGFVCDGTRILVFGGMVEYGRYSNE--LYELQASRWLWKKVKPHP 117

Query: 332 EEHGAP 337
              G P
Sbjct: 118 PPSGLP 123


>gi|16945972 kelch domain containing 3 [Homo sapiens]
          Length = 382

 Score = 67.4 bits (163), Expect = 4e-11
 Identities = 64/248 (25%), Positives = 100/248 (40%), Gaps = 30/248 (12%)

Query: 119 RFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGAT 178
           R+ HS    D    ++     T+ +CN     L+  D+N+ +W  P  SG+ P  + G +
Sbjct: 77  RYGHSTVLIDDTVLLWGGRNDTEGACNV----LYAFDVNTHKWFTPRVSGTVPGARDGHS 132

Query: 179 LVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAG-HSS 237
             V   ++ +FGG+ +       Q + F ++IH    S   W  I T   P      HS+
Sbjct: 133 ACVLGKIMYIFGGYEQ-------QADCFSNDIHKLDTSTMTWTLICTKGSPARWRDFHSA 185

Query: 238 CVIDDKMIVFGG---SLGSRQMSNDVW-----VLDLEQWAWSKPNISGPSP-HPRGGQSQ 288
            ++   M VFGG     G    +N+++     V D    AW       P+P  P G +S 
Sbjct: 186 TMLGSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEAWLD---CPPTPVLPEGRRSH 242

Query: 289 IVID-DATILILGGCGGP-NALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELWCHPACR 346
                +  + I GG     N  F D W  +  S  W     K+E +  G         C 
Sbjct: 243 SAFGYNGELYIFGGYNARLNRHFHDLWKFNPVSFTWK----KIEPKGKGPCPRRRQCCCI 298

Query: 347 VGQCVVVF 354
           VG  +V+F
Sbjct: 299 VGDKIVLF 306



 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 53/210 (25%), Positives = 89/210 (42%), Gaps = 7/210 (3%)

Query: 113 GTPITQRFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPS 172
           GT    R  HSAC     + MY+FGG  Q + +   ND+ +LD ++  W      GS   
Sbjct: 122 GTVPGARDGHSACVL--GKIMYIFGGYEQQA-DCFSNDIHKLDTSTMTWTLICTKGSPAR 178

Query: 173 PKAGATLVVYKDLLVLFGGWT-RPSPYPLHQPERFFDEIHTYSP-SKNWWNCIVTTHGPP 230
            +   +  +    + +FGG   R  P+  +  E + + I  +   ++ W +C  T   P 
Sbjct: 179 WRDFHSATMLGSHMYVFGGRADRFGPFHSNN-EIYCNRIRVFDTRTEAWLDCPPTPVLPE 237

Query: 231 PMAGHSSCVIDDKMIVFGG-SLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQI 289
               HS+   + ++ +FGG +    +  +D+W  +   + W K    G  P PR  Q   
Sbjct: 238 GRRSHSAFGYNGELYIFGGYNARLNRHFHDLWKFNPVSFTWKKIEPKGKGPCPRRRQCCC 297

Query: 290 VIDDATILILGGCGGPNALFKDAWLLHMHS 319
           ++ D  +L  G    P     D + L  HS
Sbjct: 298 IVGDKIVLFGGTSPSPEEGLGDEFDLIDHS 327



 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 34/88 (38%), Positives = 45/88 (51%), Gaps = 6/88 (6%)

Query: 112 PGTPITQ--RFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGS 169
           P TP+    R SHSA  Y  N  +Y+FGG   +  N  F+DLW+ +  S  W +    G 
Sbjct: 230 PPTPVLPEGRRSHSAFGY--NGELYIFGGYN-ARLNRHFHDLWKFNPVSFTWKKIEPKGK 286

Query: 170 YPSPKAGATLVVYKDLLVLFGGWTRPSP 197
            P P+      +  D +VLFGG T PSP
Sbjct: 287 GPCPRRRQCCCIVGDKIVLFGG-TSPSP 313


>gi|21314675 kelch domain containing 4 [Homo sapiens]
          Length = 520

 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 56/210 (26%), Positives = 94/210 (44%), Gaps = 31/210 (14%)

Query: 114 TPITQRFSHSACYY-DANQSMYVFGGCTQSSCNAAF---NDLWRLDLNSKEWIRPLASGS 169
           +P  +R +H A         ++VFGG   S     F    DLW L L +K W +  ++G 
Sbjct: 114 SPPPRRCAHQAVVVPQGGGQLWVFGGEFASPNGEQFYHYKDLWVLHLATKTWEQVKSTGG 173

Query: 170 YPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQPER---FFDEIHTYSPSKNWWNCIVTT 226
            PS ++G  +V +K  L+LFGG+        H+  R   ++++++ ++     W+ +  +
Sbjct: 174 -PSGRSGHRMVAWKRQLILFGGF--------HESTRDYIYYNDVYAFNLDTFTWSKLSPS 224

Query: 227 H-GPPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDV---------WVLDLE-----QWAWS 271
             GP P +G    V     IV  G    +++  DV         ++L  E     +W W+
Sbjct: 225 GTGPTPRSGCQMSVTPQGGIVVYGGYSKQRVKKDVDKGTRHSDMFLLKPEDGREDKWVWT 284

Query: 272 KPNISGPSPHPRGGQSQIVIDDATILILGG 301
           + N SG  P PR G S  +  +   L  GG
Sbjct: 285 RMNPSGVKPTPRSGFSVAMAPNHQTLFFGG 314



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 47/203 (23%), Positives = 82/203 (40%), Gaps = 11/203 (5%)

Query: 106 SRTYPYPGTPITQRFSHSACYYDANQSMYVFGG-CTQSSCNAAFNDLWRLDLNSKEWIRP 164
           ++T   P  P + R + S   +     + +FGG          +N+L+  +     W + 
Sbjct: 51  TQTVELPCPPPSPRLNASLSVHPEKDELILFGGEYFNGQKTFLYNELYVYNTRKDTWTKV 110

Query: 165 LASGSYPSPKAGATLVVYK---DLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWN 221
                 P   A   +VV +    L V  G +  P+    +     + ++     +   W 
Sbjct: 111 DIPSPPPRRCAHQAVVVPQGGGQLWVFGGEFASPNGEQFYH----YKDLWVLHLATKTWE 166

Query: 222 CIVTTHGPPPMAGHSSCVIDDKMIVFGGSLGSRQ---MSNDVWVLDLEQWAWSKPNISGP 278
            + +T GP   +GH       ++I+FGG   S +     NDV+  +L+ + WSK + SG 
Sbjct: 167 QVKSTGGPSGRSGHRMVAWKRQLILFGGFHESTRDYIYYNDVYAFNLDTFTWSKLSPSGT 226

Query: 279 SPHPRGGQSQIVIDDATILILGG 301
            P PR G    V     I++ GG
Sbjct: 227 GPTPRSGCQMSVTPQGGIVVYGG 249



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 28/92 (30%), Positives = 47/92 (51%), Gaps = 13/92 (14%)

Query: 242 DKMIVFGGSLGSRQMS---NDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVI---DDAT 295
           D++I+FGG   + Q +   N+++V +  +  W+K +I  PSP PR    Q V+       
Sbjct: 76  DELILFGGEYFNGQKTFLYNELYVYNTRKDTWTKVDI--PSPPPRRCAHQAVVVPQGGGQ 133

Query: 296 ILILGG-CGGPNAL----FKDAWLLHMHSGPW 322
           + + GG    PN      +KD W+LH+ +  W
Sbjct: 134 LWVFGGEFASPNGEQFYHYKDLWVLHLATKTW 165


>gi|47717139 leucine-zipper-like transcription regulator 1 [Homo
           sapiens]
          Length = 840

 Score = 62.8 bits (151), Expect = 1e-09
 Identities = 61/244 (25%), Positives = 95/244 (38%), Gaps = 21/244 (8%)

Query: 118 QRFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGA 177
           +R  H+   Y    ++YVFGG    +     NDL R D+    W R   +G+ P+P+   
Sbjct: 67  RRSKHTVVAY--KDAIYVFGG---DNGKTMLNDLLRFDVKDCSWCRAFTTGTPPAPRYHH 121

Query: 178 TLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSS 237
           + VVY   + +FGG+T    Y     +   D       +  W    +    P   + H +
Sbjct: 122 SAVVYGSSMFVFGGYT-GDIYSNSNLKNKNDLFEYKFATGQWTEWKIEGRLPVARSAHGA 180

Query: 238 CVIDDKMIVFGGSLGSRQMSNDVWVL---DLEQWAWSKPNISGPSPHPRGGQSQIVIDDA 294
            V  DK+ +F G  G+ ++ ND+W +   D E   W +   SG  P         V  D 
Sbjct: 181 TVYSDKLWIFAGYDGNARL-NDMWTIGLQDRELTCWEEVAQSGEIPPSCCNFPVAVCRDK 239

Query: 295 TILILGGCGG--PNALFKDAWLLHMHSGPWAWQPLKVENEEHGAPELWCHPACRVGQCVV 352
             +  G  G    N LF+             W  +  E+   G+P     P  R G  +V
Sbjct: 240 MFVFSGQSGAKITNNLFQ------FEFKDKTWTRIPTEHLLRGSPP---PPQRRYGHTMV 290

Query: 353 VFSQ 356
            F +
Sbjct: 291 AFDR 294



 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 54/209 (25%), Positives = 81/209 (38%), Gaps = 22/209 (10%)

Query: 113 GTPITQRFSHSACYYDANQSMYVFGGCT----QSSCNAAFNDLWRLDLNSKEWIRPLASG 168
           GTP   R+ HSA  Y    SM+VFGG T     +S     NDL+     + +W      G
Sbjct: 112 GTPPAPRYHHSAVVY--GSSMFVFGGYTGDIYSNSNLKNKNDLFEYKFATGQWTEWKIEG 169

Query: 169 SYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHG 228
             P  ++     VY D L +F G+   +           D   T      W     +   
Sbjct: 170 RLPVARSAHGATVYSDKLWIFAGYDGNARLNDMWTIGLQDRELTC-----WEEVAQSGEI 224

Query: 229 PPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNI------SGPSPHP 282
           PP        V  DKM VF G  G++ ++N+++  + +   W++         S P P  
Sbjct: 225 PPSCCNFPVAVCRDKMFVFSGQSGAK-ITNNLFQFEFKDKTWTRIPTEHLLRGSPPPPQR 283

Query: 283 RGGQSQIVIDDATILILGGCGG---PNAL 308
           R G + +   D  + + GG      PN L
Sbjct: 284 RYGHTMVAF-DRHLYVFGGAADNTLPNEL 311


>gi|195963410 MEF2 activating motif and SAP domain containing
           transcriptional regulator isoform 1 [Homo sapiens]
          Length = 415

 Score = 58.2 bits (139), Expect = 3e-08
 Identities = 80/264 (30%), Positives = 110/264 (41%), Gaps = 39/264 (14%)

Query: 363 PLSPSLNSRPSPISATPPALVPETREYRSQSPVRS-MDEAPCVNGRWGTLRPRA----QR 417
           PL+P+L S  +P   +P  L+PE  EY    P RS   E+P ++ RW   +PR      +
Sbjct: 46  PLAPALPSGTAPFLFSPGVLLPEP-EY--CPPWRSPKKESPKISQRWRESKPRGNLTYHQ 102

Query: 418 QTPSGSREGSLSPARGDGSPI-LNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDL 476
             P   R+GS +  + +GS +   G SL  GT     S    P    SP TP  P G   
Sbjct: 103 YMPPEPRQGSRADPQAEGSALGPPGPSLWEGT----DSQQPHPRMKPSPLTP-CPPGVP- 156

Query: 477 KIGLSLAPRRGSLPDQKDLRLGSIDLNWDLK----PASSSNPMDGMDNRTVGGSMRHPPE 532
               S  P +  L   K   L   +L   L+    P S +  M  +  R  GG+   PP 
Sbjct: 157 --SPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSM--LLERMRGGA---PPR 209

Query: 533 QTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQS 592
           +       P    + AGA  P    ++L A +   S  PSA A+  PPL  +  +PG   
Sbjct: 210 E----RPKPRREDSPAGAPWPRLKPKALAAARRQGSVKPSA-ASHRPPLPRAADTPG--- 261

Query: 593 LSSGETVPIPRPGPAQGDGHSLPP 616
                T P P P PA     +L P
Sbjct: 262 -----TAPAPTPTPAPAAAPALTP 280



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 72/269 (26%), Positives = 95/269 (35%), Gaps = 46/269 (17%)

Query: 273 PNISGPSPHPRGGQSQIV-IDDATILILGGC----GGPNALFKDAWLLHMHSGPWAWQPL 327
           P +  PSP P   + Q + +++ T+  L       G P +  K   L  M  G    +  
Sbjct: 153 PGVPSPSPPPHKLELQTLKLEELTVSELRQQLRLRGLPVSGTKSMLLERMRGGAPPRERP 212

Query: 328 KVENEEHGAPELWCH-------PACRVGQCVVVFSQAPSGRAPLSPSLNS-------RPS 373
           K   E+  A   W          A R G    V   A S R PL  + ++        P+
Sbjct: 213 KPRREDSPAGAPWPRLKPKALAAARRQGS---VKPSAASHRPPLPRAADTPGTAPAPTPT 269

Query: 374 PISATPPALVPE--------TREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSGSRE 425
           P  A  PAL P         T E   Q  +R     P   G    L  + +   P     
Sbjct: 270 PAPAAAPALTPSSGPGSAALTLEEELQEAIRRAQLLPN-RGIDDILEDQVEPDDP----- 323

Query: 426 GSLSPARGD--GS-PILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGLSL 482
             L P   D  GS  +L+    S G ++V  SSL SP  + SPS     +  D    LS 
Sbjct: 324 --LPPIPLDFPGSFDVLSPSPDSEGLSSVFSSSLPSPTNSSSPSPRDPTDSLDWLEALSG 381

Query: 483 APRRGSLPD-----QKDLRLGSIDLNWDL 506
            P  GS P        DL   S    WDL
Sbjct: 382 GPPLGSGPPPPSIFSADLSDSSSSRLWDL 410


>gi|145701025 multiple EGF-like-domains 8 [Homo sapiens]
          Length = 2778

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 73/277 (26%), Positives = 109/277 (39%), Gaps = 48/277 (17%)

Query: 113  GTPITQRFSHSACYYDANQSMYVFGGCT-QSSCNAAFNDLWRLDLNSKEWIRPLASGSYP 171
            GTP T  + HSA Y++A  S+YVFGG        A   +L+ L    + W       S  
Sbjct: 1599 GTPPTGLYGHSAVYHEATDSLYVFGGFRFHVELAAPSPELYSLHCPDRTW-------SLL 1651

Query: 172  SPKAGATLVVYKDLLVLFGGWTRP-SPYPLHQPERF-FDEIHTYSPSKNWWNCIVTTHG- 228
            +P  GA     +D +    G +R     P  QP  + F E+         W  +  T G 
Sbjct: 1652 APSQGAK----RDRMRNVRGSSRGLGQVPGEQPGSWGFREVR---KKMALWAALAGTGGF 1704

Query: 229  ----------PPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNIS-- 276
                      P P   H+S ++ D M+V GG     + S+DV +  +   AW  P+++  
Sbjct: 1705 LEEISPHLKEPRPRLFHASALLGDTMVVLGGRSDPDEFSSDVLLYQVNCNAWLLPDLTRS 1764

Query: 277  ---GPSPHPRGGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVENEE 333
               GP P        +    + + I GG GG  AL +   LL +   P    P ++ +  
Sbjct: 1765 ASVGP-PMEESVAHAVAAVGSRLYISGGFGGV-ALGR---LLALTLPP---DPCRLLSSP 1816

Query: 334  HGAPE----LWCHPACRVGQCVVVFSQAPSGRAPLSP 366
                +     WCH AC  G       +   G +P SP
Sbjct: 1817 EACNQSGACTWCHGACLSGDQA---HRLGCGGSPCSP 1850



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 32/140 (22%), Positives = 53/140 (37%), Gaps = 22/140 (15%)

Query: 166 ASGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVT 225
           A+G++ SP           LL +FGG                 ++  Y+ S N W     
Sbjct: 231 AAGAFLSPPG---------LLAVFGG---------QDLNNALGDLVLYNFSANTWESWDL 272

Query: 226 THGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLD-LEQWAW---SKPNISGPSPH 281
           +  P     H +      +++ GG L    ++NDVW    L +  W   + P  S   P 
Sbjct: 273 SPAPAARHSHVAVAWAGSLVLMGGELADGSLTNDVWAFSPLGRGHWELLAPPASSSSGPP 332

Query: 282 PRGGQSQIVIDDATILILGG 301
              G +  ++DD  + + GG
Sbjct: 333 GLAGHAAALVDDVWLYVSGG 352



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 46/203 (22%), Positives = 77/203 (37%), Gaps = 25/203 (12%)

Query: 122 HSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKE-WIRPLASGSYPSPKAGATLV 180
           H+A   D +  +YV GG T     ++    +RLD  S   W + + +G  P    G ++V
Sbjct: 337 HAAALVD-DVWLYVSGGRTPHDLFSSGLFRFRLDSTSGGYWEQVIPAGGRPPAATGHSMV 395

Query: 181 VYK-DLLVLFGGWTRPSP----YPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGH 235
            +     +L  G  RPS       ++  E F  + H ++  K          GP   A H
Sbjct: 396 FHAPSRALLVHGGHRPSTARFSVRVNSTELFHVDRHVWTTLKGRDGL----QGPRERAFH 451

Query: 236 SSCVIDDKMIVFGGSLGSRQMSNDV--------------WVLDLEQWAWSKPNISGPSPH 281
           ++ V+ + M+V+GG++ +                     WV   E      P      P 
Sbjct: 452 TASVLGNYMVVYGGNVHTHYQEEKCYEDGIFFYHLGCHQWVSGAELAPPGTPEGRAAPPS 511

Query: 282 PRGGQSQIVIDDATILILGGCGG 304
            R      V+  + +L+ GG  G
Sbjct: 512 GRYSHVAAVLGGSVLLVAGGYSG 534



 Score = 33.9 bits (76), Expect = 0.54
 Identities = 36/159 (22%), Positives = 63/159 (39%), Gaps = 19/159 (11%)

Query: 174  KAGATLVVYKDL-LVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTH----- 227
            + G T+V   D  L +FGG        L  P+     ++ YS S+  W  ++        
Sbjct: 1443 RLGHTMVDGPDATLWMFGG--------LGLPQGLLGNLYRYSVSERRWTQMLAGAEDGGP 1494

Query: 228  GPPPMAGHSSCVID---DKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPR- 283
            GP P + H++  +      M + GG L +  ++ D WVL+L    W +         P  
Sbjct: 1495 GPSPRSFHAAAYVPAGRGAMYLLGG-LTAGGVTRDFWVLNLTTLQWRQEKAPQTVELPAV 1553

Query: 284  GGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPW 322
             G +       ++L++GG    N   +      + +G W
Sbjct: 1554 AGHTLTARRGLSLLLVGGYSPENGFNQQLLEYQLATGTW 1592


>gi|33695109 Rab9 effector protein with kelch motifs [Homo sapiens]
          Length = 372

 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 42/149 (28%), Positives = 65/149 (43%), Gaps = 14/149 (9%)

Query: 105 ESRTYPYP---GTPITQRFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEW 161
           E+RT+  P     P + R  H++     NQ +YVFGG  + +       L   D N+  W
Sbjct: 122 ETRTWTTPEVTSPPPSPRTFHTSSAAIGNQ-LYVFGGGERGAQPVQDTKLHVFDANTLTW 180

Query: 162 IRPLASGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWN 221
            +P   G+ PSP+ G  +V     L + GG            +RF+D++H    S   W 
Sbjct: 181 SQPETLGNPPSPRHGHVMVAAGTKLFIHGGLA---------GDRFYDDLHCIDISDMKWQ 231

Query: 222 CIVTTHGPPP-MAGHSSCVIDDKMIVFGG 249
            +  T   P   A HS+  +   + +FGG
Sbjct: 232 KLNPTGAAPAGCAAHSAVAMGKHVYIFGG 260



 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 68/268 (25%), Positives = 100/268 (37%), Gaps = 37/268 (13%)

Query: 108 TYPYPGTPITQRFSHSACYYDA-----NQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEWI 162
           T   PG     R  HS  Y           +++ GG      N +F+D+  +DL   +W 
Sbjct: 20  TLTVPGDSPCARVGHSCSYLPPVGNAKRGKVFIVGGANP---NRSFSDVHTMDLGKHQWD 76

Query: 163 RPLASGSYPSPKAGATL-VVYKDLLVLFGGWTRPSPYPLHQ---PERFFDEIHTYSPSKN 218
                G  P  +  + +     D + +FGG  +       Q   PE           ++ 
Sbjct: 77  LDTCKGLLPRYEHASFIPSCTPDRIWVFGGANQSGNRNCLQVLNPE-----------TRT 125

Query: 219 WWNCIVTTHGPPPMAGH-SSCVIDDKMIVFGGSLGSRQMSND--VWVLDLEQWAWSKPNI 275
           W    VT+  P P   H SS  I +++ VFGG     Q   D  + V D     WS+P  
Sbjct: 126 WTTPEVTSPPPSPRTFHTSSAAIGNQLYVFGGGERGAQPVQDTKLHVFDANTLTWSQPET 185

Query: 276 SGPSPHPRGGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEHG 335
            G  P PR G   +V     + I GG  G +  + D   + +      WQ L       G
Sbjct: 186 LGNPPSPRHGH-VMVAAGTKLFIHGGLAG-DRFYDDLHCIDI--SDMKWQKL----NPTG 237

Query: 336 APELWC--HPACRVGQCVVVF-SQAPSG 360
           A    C  H A  +G+ V +F    P+G
Sbjct: 238 AAPAGCAAHSAVAMGKHVYIFGGMTPAG 265



 Score = 53.9 bits (128), Expect = 5e-07
 Identities = 58/234 (24%), Positives = 93/234 (39%), Gaps = 21/234 (8%)

Query: 100 GNIQWESRTYPYPGTPITQRFSHSACYYDANQS-MYVFGGCTQSSCNAAFNDLWRLDLNS 158
           G  QW+  T       +  R+ H++         ++VFGG  QS      N L  L+  +
Sbjct: 71  GKHQWDLDTCK----GLLPRYEHASFIPSCTPDRIWVFGGANQSGNR---NCLQVLNPET 123

Query: 159 KEWIRPLASGSYPSPKAGATL-VVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSK 217
           + W  P  +   PSP+   T      + L +FGG  R +     QP +   ++H +  + 
Sbjct: 124 RTWTTPEVTSPPPSPRTFHTSSAAIGNQLYVFGGGERGA-----QPVQD-TKLHVFDANT 177

Query: 218 NWWNCIVTTHGPP-PMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNIS 276
             W+   T   PP P  GH       K+ + GG  G R   +D+  +D+    W K N +
Sbjct: 178 LTWSQPETLGNPPSPRHGHVMVAAGTKLFIHGGLAGDR-FYDDLHCIDISDMKWQKLNPT 236

Query: 277 GPSPHPRGGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVE 330
           G +P      S + +    + I GG     AL     +   H+    W  LK +
Sbjct: 237 GAAPAGCAAHSAVAM-GKHVYIFGGMTPAGAL---DTMYQYHTEEQHWTLLKFD 286


>gi|44917619 kelch domain containing 10 [Homo sapiens]
          Length = 442

 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 52/186 (27%), Positives = 82/186 (44%), Gaps = 23/186 (12%)

Query: 130 NQSMYVFGGCTQSSCNAA---------FNDLWRLDLNSKEWIRPLASGSYPSPKAGATLV 180
           N ++YVFGG       +          F +LWR    +  W +    G  P   A  +LV
Sbjct: 101 NTNLYVFGGYNPDYDESGGPDNEDYPLFRELWRYHFATGVWHQMGTDGYMPRELASMSLV 160

Query: 181 VYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPP--MAGHSSC 238
           ++ + L++FGG   P        E   +++H  +     W  +++  G  P  + G +  
Sbjct: 161 LHGNNLLVFGGTGIPF------GESNGNDVHVCNVKYKRW-ALLSCRGKKPSRIYGQAMA 213

Query: 239 VIDDKMIVFGGSLGSRQMSNDVWVLDL--EQWAWSKP-NISGPSPHPRGGQSQIVIDDAT 295
           +I+  + VFGG+ G    S D+  LDL   +W   KP N+S   P  R  + +I  D   
Sbjct: 214 IINGSLYVFGGTTG-YIYSTDLHKLDLNTREWTQLKPNNLSCDLPEER-YRHEIAHDGQR 271

Query: 296 ILILGG 301
           I ILGG
Sbjct: 272 IYILGG 277



 Score = 53.1 bits (126), Expect = 9e-07
 Identities = 46/159 (28%), Positives = 70/159 (44%), Gaps = 19/159 (11%)

Query: 130 NQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEW--IRPL-ASGSYPSPKAGATLVVYKDLL 186
           N S+YVFGG T    +    DL +LDLN++EW  ++P   S   P  +    +      +
Sbjct: 216 NGSLYVFGGTTGYIYST---DLHKLDLNTREWTQLKPNNLSCDLPEERYRHEIAHDGQRI 272

Query: 187 VLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHG-----PPPMAGHSSCVID 241
            + GG T  + Y L++       IH Y+   N W  I T        P     HS   I 
Sbjct: 273 YILGGGTSWTAYSLNK-------IHAYNLETNAWEEIATKPHEKIGFPAARRCHSCVQIK 325

Query: 242 DKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSP 280
           + + + GG  G   +  D+W L+L+ + W K   + P P
Sbjct: 326 NDVFICGGYNGE-VILGDIWKLNLQTFQWVKLPATMPEP 363



 Score = 37.7 bits (86), Expect = 0.037
 Identities = 46/200 (23%), Positives = 77/200 (38%), Gaps = 13/200 (6%)

Query: 171 PSPKAGATLVVYKDLLVLFGGWTRP---SPYPLHQPERFFDEIHTYSPSKNWWNCIVTT- 226
           P  ++G   V     L +FGG+      S  P ++    F E+  Y  +   W+ + T  
Sbjct: 89  PPARSGHRCVADNTNLYVFGGYNPDYDESGGPDNEDYPLFRELWRYHFATGVWHQMGTDG 148

Query: 227 HGPPPMAGHSSCVIDDKMIVFGGS---LGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPR 283
           + P  +A  S  +  + ++VFGG+    G     NDV V +++   W+  +  G  P   
Sbjct: 149 YMPRELASMSLVLHGNNLLVFGGTGIPFGESN-GNDVHVCNVKYKRWALLSCRGKKPSRI 207

Query: 284 GGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVENEEHGAP-ELWCH 342
            GQ+  +I+ +  +     GG         L  +      W  LK  N     P E + H
Sbjct: 208 YGQAMAIINGSLYVF----GGTTGYIYSTDLHKLDLNTREWTQLKPNNLSCDLPEERYRH 263

Query: 343 PACRVGQCVVVFSQAPSGRA 362
                GQ + +     S  A
Sbjct: 264 EIAHDGQRIYILGGGTSWTA 283


>gi|20143482 melanoma antigen family E, 1 [Homo sapiens]
          Length = 957

 Score = 50.4 bits (119), Expect = 6e-06
 Identities = 78/299 (26%), Positives = 101/299 (33%), Gaps = 43/299 (14%)

Query: 343 PACRVGQCVVVFSQAPSGRAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAP 402
           P    G C  V   A  GR        SRP   S  P   VP T      S V S    P
Sbjct: 118 PTISKGLCTSVTLAASEGRN------TSRPPTSSEEPSTSVPPTA-----SEVPSTSLPP 166

Query: 403 CVNGRWGTLRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAA--VGGSSLDSPV 460
                  T  P    + PS S   +  P  G  + +L      PGT+        L + V
Sbjct: 167 TPGEGTSTSVPPTAYEGPSTSVVPT--PDEGPSTSVLPTPGEGPGTSVPLAATEGLSTSV 224

Query: 461 QAI---SPST---PSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNP 514
           QA     PST   P+A EG    +   + P R   P            +  + PA+S   
Sbjct: 225 QATPDEGPSTSVPPTATEG----LSTPVPPTRDEGPSTSVPATPGEGPSTSVLPAASDGQ 280

Query: 515 MDGM-DNRTVGGSMRHPPEQTNGVHT--------------PPHVASALAGAVSPGALRRS 559
              +   R  G S   PP  T G+ T              PP     L+ +V P A    
Sbjct: 281 SISLVPTRGKGSSTSVPPTATEGLSTSVQPTAGEGSSTSVPPTPGGGLSTSVPPTATEEL 340

Query: 560 LEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVPIPRPGPAQGDGHSLPPIA 618
             ++     +GPS S    P  G S   P + S  S  +VP   P P +G    + P A
Sbjct: 341 STSVPPTPGEGPSTSVLPIPGEGLSTSVPPTASDGSDTSVP---PTPGEGASTLVQPTA 396


>gi|46410931 attractin-like 1 [Homo sapiens]
          Length = 1379

 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 45/183 (24%), Positives = 82/183 (44%), Gaps = 14/183 (7%)

Query: 87  HQCYHGFMKAVQEGNIQWESRTYPYP---GTPITQRFSHSACYYDANQSMYVFGGCTQSS 143
           +   +G+  ++QE +I   S T+  P   G  +   + H++ Y +  +S+YV GG     
Sbjct: 434 YSAIYGYTSSIQEYHIS--SNTWLVPETKGAIVQGGYGHTSVYDEITKSIYVHGGYKALP 491

Query: 144 CN--AAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLH 201
            N     +DL++ ++N+K W     SG     +   + V+    +++FGG T       +
Sbjct: 492 GNKYGLVDDLYKYEVNTKTWTILKESGF---ARYLHSAVLINGAMLIFGGNTHNDTSLSN 548

Query: 202 QPERFFDEIHTYSPSKNWWNCIV--TTHGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSND 259
             + F  +   Y  + + W  +     H      GHS+ VI+  M +FGG   S  + ND
Sbjct: 549 GAKCFSADFLAYDIACDEWKILPKPNLHRDVNRFGHSAVVINGSMYIFGGF--SSVLLND 606

Query: 260 VWV 262
           + V
Sbjct: 607 ILV 609



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 41/191 (21%), Positives = 78/191 (40%), Gaps = 25/191 (13%)

Query: 149 NDLWR-----LDLNSKE--WIRPLASGSYPSP-KAGATLVVYKDLLVLFGGWTRPSPYPL 200
           ND W+     L++ S E  WI P      PS  +A    V++   + + GG+T       
Sbjct: 272 NDSWQGPDCSLNVPSTESYWILPNVKPFSPSVGRASHKAVLHGKFMWVIGGYTFNYSS-- 329

Query: 201 HQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVIDDKMIVFGGSLGSR--QMSN 258
                 F  +  Y+   + WN    + GP    GHS  +  + + ++GG + +    +++
Sbjct: 330 ------FQMVLNYNLESSIWNVGTPSRGPLQRYGHSLALYQENIFMYGGRIETNDGNVTD 383

Query: 259 DVWVLDLEQWAWS--KPNISG-PSPHPRGGQSQIVID----DATILILGGCGGPNALFKD 311
           ++WV ++   +WS   P + G    +   G S  +++    D  ++I+ G          
Sbjct: 384 ELWVFNIHSQSWSTKTPTVLGHGQQYAVEGHSAHIMELDSRDVVMIIIFGYSAIYGYTSS 443

Query: 312 AWLLHMHSGPW 322
               H+ S  W
Sbjct: 444 IQEYHISSNTW 454



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 15/52 (28%), Positives = 29/52 (55%), Gaps = 5/52 (9%)

Query: 113 GTPIT---QRFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEW 161
           GTP     QR+ HS   Y  N  ++++GG  +++     ++LW  +++S+ W
Sbjct: 346 GTPSRGPLQRYGHSLALYQEN--IFMYGGRIETNDGNVTDELWVFNIHSQSW 395


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 49.7 bits (117), Expect = 9e-06
 Identities = 69/284 (24%), Positives = 103/284 (36%), Gaps = 31/284 (10%)

Query: 357  APSGRAPLSPSLNSRPSPISATPPALV--PETREYRSQSPVRSMDEAPCVNGR-WGTLRP 413
            +P G  P +PS    P+P + TPP+    P    +   +        P   G    T  P
Sbjct: 995  SPKG-GPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLP 1053

Query: 414  RAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGT---AAVGGSSLDSPVQAISP--STP 468
            +    TP+ +     SP  G  +P L G    P     +  GG +  SP  A  P  +TP
Sbjct: 1054 KGAPTTPAATLP---SPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATP 1110

Query: 469  SAPEGYDLKIGLSLAPRRGSL-------PDQKDLRLGSIDLNWDLKPASSS-NPMDGMDN 520
             +P+G     GL+  P +G+        P  K              PA++  +P  G+  
Sbjct: 1111 PSPKG-----GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLAT 1165

Query: 521  RTVGGS----MRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAA 576
                G+       PP    G+ TP    +    A +P + +  L       +    A+  
Sbjct: 1166 PPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1225

Query: 577  LSPPLGSSPGSPGSQSLSSGETVPIPRPGPA--QGDGHSLPPIA 618
             SP  G +  SP     +   T P P+ GPA     G   PP A
Sbjct: 1226 PSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAA 1269



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 66/273 (24%), Positives = 102/273 (37%), Gaps = 45/273 (16%)

Query: 357  APSGRAPLSPSLNSRPSPISATPPALVPE----TREYRSQSPVRSMDEAPCVNGRWGTLR 412
            +P G  P +PS    P P +ATPP+  P+    T  ++  +P       P   G   T  
Sbjct: 1089 SPKG-GPATPSPKGAPMPPAATPPS--PKGGLATPPHKG-APTTPAATPPSPKGGLATPP 1144

Query: 413  PRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGT---AAVGGSSLDSPVQAISP--ST 467
            P+    TP+ +     SP  G  +P   G   +P     +  GG +  SP  A +   +T
Sbjct: 1145 PKGAPTTPAATPP---SPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1201

Query: 468  PSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGS- 526
            P +P+G     GL+    +G+                    A+  +P  G+   +  G+ 
Sbjct: 1202 PPSPKG-----GLATPSPKGAPTTPA---------------ATPPSPKGGLATPSPKGAP 1241

Query: 527  ---MRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGS 583
                  PP    G  TPP   +    A +P +L+  L        KG    A ++PP  S
Sbjct: 1242 TTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGL---ATPPHKGAPNPAVVTPP--S 1296

Query: 584  SPGSPGSQSLSSGETVPIPRPGPAQGDGHSLPP 616
              G P +       T P   P   +G   + PP
Sbjct: 1297 PKGGPATSPPKGAPTPPAATPPSPKGSPGTPPP 1329



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 64/268 (23%), Positives = 91/268 (33%), Gaps = 23/268 (8%)

Query: 357  APSGRAPLSPSLNSRPSPISATPPALV--PETREYRSQSPVRSMDEAPCVNGRWGTLRPR 414
            AP G  P SPS    P+P +ATPP+    P T   +  +P       P   G   T  P+
Sbjct: 926  APKG-IPASPSPKGAPTPPAATPPSPKGGPATPSPK-WAPTPPAATPPSPKGGPATPSPK 983

Query: 415  AQRQTPSGSREGSLSPARGDGSPILNGGSLSPGT----------AAVGGSSLDSPVQAIS 464
                 P+ +     SP  G  +P   G    P            A        +P  A  
Sbjct: 984  GAPTPPAATPP---SPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATP 1040

Query: 465  PSTPSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSS-NPMDGMDNRTV 523
            PS   +P    L  G    P   +LP  K              PA++  +P  G    + 
Sbjct: 1041 PSPKGSPAATPLPKGAPTTPA-ATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP 1099

Query: 524  GGS----MRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSP 579
             G+       PP    G+ TPPH  +    A +P + +  L       +    A+   SP
Sbjct: 1100 KGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1159

Query: 580  PLGSSPGSPGSQSLSSGETVPIPRPGPA 607
              G +   P     +   T P P+ G A
Sbjct: 1160 KGGLATPPPKGAPTTPAATPPSPKGGLA 1187



 Score = 39.3 bits (90), Expect = 0.013
 Identities = 63/276 (22%), Positives = 99/276 (35%), Gaps = 43/276 (15%)

Query: 362  APLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPS 421
            AP +PS     S  +++PPA+ P T  Y+     + +   P V        P     TP 
Sbjct: 1570 APATPS-----SKEASSPPAVTPST--YKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPP 1622

Query: 422  GSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGLS 481
                   SP +G  +P   G   SP    V  SSL          +P++P     K+G +
Sbjct: 1623 -------SPEKGPATPAPKGTPTSP---PVTPSSLKD--------SPTSPASVTCKMGAT 1664

Query: 482  LAPRRGSLPDQKDLRLGSIDLNWDL-KPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTP 540
            +      LP +K    G   L   L  PA  S P+     R      + P  + +   +P
Sbjct: 1665 VPQASKGLPAKK----GPTALKEVLVAPAPESTPIITAPTR------KGPQTKKSSATSP 1714

Query: 541  PHVASALAGAVSPGALRR-------SLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSL 593
            P      A   S G L          ++   + ++KG  AS +   PL        +   
Sbjct: 1715 PICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLT 1774

Query: 594  SSGETVPIPRPGPAQGDGHSLPPIARRLGHHPPQSL 629
            ++     +P+P  A       PP++  L   P  +L
Sbjct: 1775 AAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTL 1810



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 74/296 (25%), Positives = 111/296 (37%), Gaps = 37/296 (12%)

Query: 354  FSQAPSGRAPLSPSLNSRPSPISA-TPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLR 412
            +  APS +  L P   + PSP  A TPPA+ P            S ++ P      GT  
Sbjct: 1590 YKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPP-----------SPEKGPATPAPKGT-- 1636

Query: 413  PRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPG-TAAVGGSSLDSPVQAISP-STP-- 468
            P +   TPS  ++   SPA             S G  A  G ++L   + A +P STP  
Sbjct: 1637 PTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPII 1696

Query: 469  SAP--EGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGS 526
            +AP  +G   K   + +P     P  K+   G +     + PA              G  
Sbjct: 1697 TAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLS---TVAPAPLLPVQKDSSKTAKGKD 1753

Query: 527  MRHPPEQTNGVHTPPH--VASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSP-PLGS 583
              H P+   G   PP    ++ L  A     L +  E+    ++  P  S  L+P P+ +
Sbjct: 1754 ASHSPK---GPLAPPESKASTPLTAAAFEKVLPKP-ESASVSAAPSPPVSLPLAPSPVPT 1809

Query: 584  SPGSPGSQSLSSGETVPIPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKPLYQSM 639
             P        S G  +  P    A  D   L P+       PP+ ++ G P +QS+
Sbjct: 1810 LPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLI------PPEPISGGVP-FQSV 1858



 Score = 33.9 bits (76), Expect = 0.54
 Identities = 63/269 (23%), Positives = 100/269 (37%), Gaps = 38/269 (14%)

Query: 357  APSGRAPLSPSLNSRPSPISATPPALVP--ETREYRSQSPVRSMDEAPCVNGRWGTLRPR 414
            +P G  P +P     P+P +ATPP+L     T  ++  +P  ++   P   G   T  P+
Sbjct: 1250 SPKG-GPATPPPKGAPTPPAATPPSLKGGLATPPHKG-APNPAVVTPPSPKGGPATSPPK 1307

Query: 415  AQRQTPSGSREGSLSPARGDGSPILNGGSLSPGT---AAVGGSSLDS--PVQAISPSTPS 469
                 P+ +     SP    G+P   G    P     +  G  +L +  P     P+TPS
Sbjct: 1308 GAPTPPAATPP---SPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPS 1364

Query: 470  APEGY-------DLKIGLSL---APRRG-SLPDQKDLRLGSIDLNWDLKPASSSNPMDGM 518
            + EG          K G ++   +P+RG ++P  K        +    K A ++ P+   
Sbjct: 1365 SKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPAT-PVTRE 1423

Query: 519  DNRTVGGSMRHPPEQTN-GVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAAL 577
               T       PP  T   +   P  ++   G  +P             SSKG     A+
Sbjct: 1424 GAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATP-------------SSKGDPTLPAV 1470

Query: 578  SPPLGSSPGSPGSQSLSSGETVPIPRPGP 606
            +PP    P +P   + SS        P P
Sbjct: 1471 TPPSPKEPPAPKQVATSSSPKKAPATPAP 1499


>gi|21450863 attractin isoform 2 [Homo sapiens]
          Length = 1272

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 44/186 (23%), Positives = 83/186 (44%), Gaps = 10/186 (5%)

Query: 87  HQCYHGFMKAVQEGNIQWESRTYPYP-GTPITQRFSHSACYYDANQSMYVFGGCTQSSCN 145
           H   +G++  VQE ++   + +  +  G  +   + HS+ Y    +++YV GG    S N
Sbjct: 467 HCPLYGYISNVQEYDLDKNTWSILHTQGALVQGGYGHSSVYDHRTRALYVHGGYKAFSAN 526

Query: 146 --AAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQP 203
                +DL+R D++++ W     S  +   +   T V+    +++FGG T       H  
Sbjct: 527 KYRLADDLYRYDVDTQMWTILKDSRFF---RYLHTAVIVSGTMLVFGGNTHNDTSMSHGA 583

Query: 204 ERFFDEIHTYSPSKNWWNCI--VTTHGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVW 261
           + F  +   Y  + + W+ +     H      GHS+ + +  M VFGG   +  + +D+ 
Sbjct: 584 KCFSSDFMAYDIACDRWSVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGF--NSLLLSDIL 641

Query: 262 VLDLEQ 267
           V   EQ
Sbjct: 642 VFTSEQ 647



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 37/162 (22%), Positives = 69/162 (42%), Gaps = 13/162 (8%)

Query: 133 MYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLFGGW 192
           M+V GG   +  ++ +N +   DL S+EW+    S +    + G +L +YKD + ++GG 
Sbjct: 353 MWVVGGYMFN--HSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALYKDKIYMYGGK 410

Query: 193 TRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVIDDK-----MIVF 247
              +    ++   F   IH    +++W            + GHS+ ++  K     M+V 
Sbjct: 411 IDSTGNVTNELRVF--HIH----NESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVVMLVI 464

Query: 248 GGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQI 289
            G        ++V   DL++  WS  +  G       G S +
Sbjct: 465 FGHCPLYGYISNVQEYDLDKNTWSILHTQGALVQGGYGHSSV 506



 Score = 30.4 bits (67), Expect = 6.0
 Identities = 23/92 (25%), Positives = 35/92 (38%)

Query: 231 PMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIV 290
           P A H + V  + M V GG + +    N V   DL    W   N S  +   R G S  +
Sbjct: 340 PRASHKAVVNGNIMWVVGGYMFNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLAL 399

Query: 291 IDDATILILGGCGGPNALFKDAWLLHMHSGPW 322
             D   +  G       +  +  + H+H+  W
Sbjct: 400 YKDKIYMYGGKIDSTGNVTNELRVFHIHNESW 431


>gi|21450861 attractin isoform 1 [Homo sapiens]
          Length = 1429

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 44/186 (23%), Positives = 83/186 (44%), Gaps = 10/186 (5%)

Query: 87  HQCYHGFMKAVQEGNIQWESRTYPYP-GTPITQRFSHSACYYDANQSMYVFGGCTQSSCN 145
           H   +G++  VQE ++   + +  +  G  +   + HS+ Y    +++YV GG    S N
Sbjct: 467 HCPLYGYISNVQEYDLDKNTWSILHTQGALVQGGYGHSSVYDHRTRALYVHGGYKAFSAN 526

Query: 146 --AAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQP 203
                +DL+R D++++ W     S  +   +   T V+    +++FGG T       H  
Sbjct: 527 KYRLADDLYRYDVDTQMWTILKDSRFF---RYLHTAVIVSGTMLVFGGNTHNDTSMSHGA 583

Query: 204 ERFFDEIHTYSPSKNWWNCI--VTTHGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVW 261
           + F  +   Y  + + W+ +     H      GHS+ + +  M VFGG   +  + +D+ 
Sbjct: 584 KCFSSDFMAYDIACDRWSVLPRPDLHHDVNRFGHSAVLHNSTMYVFGGF--NSLLLSDIL 641

Query: 262 VLDLEQ 267
           V   EQ
Sbjct: 642 VFTSEQ 647



 Score = 32.0 bits (71), Expect = 2.0
 Identities = 37/162 (22%), Positives = 69/162 (42%), Gaps = 13/162 (8%)

Query: 133 MYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLFGGW 192
           M+V GG   +  ++ +N +   DL S+EW+    S +    + G +L +YKD + ++GG 
Sbjct: 353 MWVVGGYMFN--HSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLALYKDKIYMYGGK 410

Query: 193 TRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVIDDK-----MIVF 247
              +    ++   F   IH    +++W            + GHS+ ++  K     M+V 
Sbjct: 411 IDSTGNVTNELRVF--HIH----NESWVLLTPKAKEQYAVVGHSAHIVTLKNGRVVMLVI 464

Query: 248 GGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQI 289
            G        ++V   DL++  WS  +  G       G S +
Sbjct: 465 FGHCPLYGYISNVQEYDLDKNTWSILHTQGALVQGGYGHSSV 506



 Score = 30.4 bits (67), Expect = 6.0
 Identities = 23/92 (25%), Positives = 35/92 (38%)

Query: 231 PMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIV 290
           P A H + V  + M V GG + +    N V   DL    W   N S  +   R G S  +
Sbjct: 340 PRASHKAVVNGNIMWVVGGYMFNHSDYNMVLAYDLASREWLPLNRSVNNVVVRYGHSLAL 399

Query: 291 IDDATILILGGCGGPNALFKDAWLLHMHSGPW 322
             D   +  G       +  +  + H+H+  W
Sbjct: 400 YKDKIYMYGGKIDSTGNVTNELRVFHIHNESW 431


>gi|146219832 myosin light chain kinase 3 [Homo sapiens]
          Length = 819

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 57/239 (23%), Positives = 88/239 (36%), Gaps = 44/239 (18%)

Query: 391 SQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAA 450
           ++ P     +A  + G    L P       +   +  +SP +GDG P        P  A 
Sbjct: 184 AREPGEESQKADVLEGTAERLPPIRASGLGADPAQAVVSPGQGDGVP-------GPAQAF 236

Query: 451 VGGSSLDSPVQAISPSTPSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKP-- 508
            G   L + V+A +P TPS     +L+ GL LAP  G        R+  +  + ++ P  
Sbjct: 237 PGHLPLPTKVEAKAPETPSE----NLRTGLELAPAPG--------RVNVVSPSLEVAPGA 284

Query: 509 ---ASSS----NPMDGMDNRTVGGSMRHP-----PEQTNGVH----TPPHVASALAGAVS 552
              ASSS     P++     T G   + P     P Q    H    TPP ++  +    +
Sbjct: 285 GQGASSSRPDPEPLEEGTRLTPGPGPQCPGPPGLPAQARATHSGGETPPRISIHIQEMDT 344

Query: 553 PGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVPIPRPGPAQGDG 611
           PG +      +    S GP+ +     P  + PG  G          P   PG    +G
Sbjct: 345 PGEM-----LMTGRGSLGPTLTT--EAPAAAQPGKQGPPGTGRCLQAPGTEPGEQTPEG 396


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 72/284 (25%), Positives = 102/284 (35%), Gaps = 32/284 (11%)

Query: 359  SGRAPLSP--SLNSRPSPI------SATPPALVPETR--EYRSQSPVRSMDEAPCVNGRW 408
            S R PLS    ++ R SP       S TPP+   ++R    R+ SP   M +AP  +   
Sbjct: 2382 SPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQS--- 2438

Query: 409  GTLRPRAQRQTPSGSREGSLSPAR---GDGSPILNGGSLSPGTAAVGGSSLDSPVQAISP 465
              L P AQ Q  S         +R      +P+    SLS G  A   SS       +S 
Sbjct: 2439 --LLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSV 2496

Query: 466  STPSAPEGY----DLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNR 521
              P  P           G        +L   K+ R  S   +     +SSS+      + 
Sbjct: 2497 PAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSS 2556

Query: 522  ------TVGGSMRHPPEQT-NGVHTP---PHVASALAGAVSPGALRRSLEAIKAMSSKGP 571
                  + G S+   PE     V +P   P  A        P   +R   +  + SS   
Sbjct: 2557 GSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSS 2616

Query: 572  SASAALSPPLGSSPGSPGSQSLSSGETVPIPRPGPAQGDGHSLP 615
            S+S++ S    SS  S  S S SS  +     P PA+    +LP
Sbjct: 2617 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALP 2660



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 68/279 (24%), Positives = 99/279 (35%), Gaps = 31/279 (11%)

Query: 367  SLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSGSREG 426
            SL +   P S +   L     +  +  P+ S+  AP  N         A R   + +   
Sbjct: 2189 SLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAAN--------LASRIPAASAAAM 2240

Query: 427  SLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPS--------TPSAPEGYDLKI 478
            +L+ AR    P     + S   AA    +L SP  A++PS        TP+AP      +
Sbjct: 2241 NLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPA-----V 2295

Query: 479  GLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTN--G 536
             L+ A    +L        G+     +  P+SS  P        VG    H     N  G
Sbjct: 2296 NLAGARTPAALAALSLTGSGTPPTAANY-PSSSRTPQAPASANLVGPRSAHATAPVNIAG 2354

Query: 537  VHTPPHVASA--LAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPL-----GSSPGSPG 589
              T   +A A   +  ++P     +L + +   S     S   SPPL       +P S  
Sbjct: 2355 SRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAP 2414

Query: 590  SQSLSSGETVPIPRPGPAQGDGHSLPPIARRLGHHPPQS 628
            SQS  + E  P P     Q    SL P A+     P  S
Sbjct: 2415 SQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPS 2453



 Score = 40.0 bits (92), Expect = 0.008
 Identities = 64/263 (24%), Positives = 98/263 (37%), Gaps = 31/263 (11%)

Query: 357  APSGRAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQ 416
            +PS R   +PS +  P P    P + VP    +  QS        P    +  +    A 
Sbjct: 2426 SPSSRMGQAPSQSLLP-PAQDQPRSPVPSA--FSDQSRCLIAQTTPVAGSQSLSSGAVAT 2482

Query: 417  RQTPSGSREGSLS-PARGD-----GSPILNGGSLSPGTAAV------GGSSLDSPVQAIS 464
              + +G   G LS PA G      G P  + G+  P   A         SS  S   + S
Sbjct: 2483 TTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSS 2542

Query: 465  PSTPSAPEGYDLKIGLSLAPRRGS-LPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTV 523
             S+ S+        G S +   GS LP Q ++ L  +       P+ +  P + +     
Sbjct: 2543 SSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRV-------PSPTPAPKEAVREG-- 2593

Query: 524  GGSMRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGS 583
                  PPE T         +S+ + + S  +   S  +  + SS   S+S++ S    S
Sbjct: 2594 -----RPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2648

Query: 584  -SPGSPGSQSLSSGETVPIPRPG 605
             SP  PG Q+L    +   P PG
Sbjct: 2649 PSPAKPGPQALPKPASPKKPPPG 2671



 Score = 38.5 bits (88), Expect = 0.022
 Identities = 77/311 (24%), Positives = 109/311 (35%), Gaps = 62/311 (19%)

Query: 363  PLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCV------NGRWGTLRPRAQ 416
            P +PS        S  P AL P+T   RS+SP        C+      +G   ++  +  
Sbjct: 1470 PRTPSRGRSECDSSPEPKAL-PQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTV 1528

Query: 417  RQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDL 476
             +TP G R  S S    D  P     S SP   +   SS DS  +  +P    +  G   
Sbjct: 1529 ARTPLGQRSRSGSSQELDVKP-----SASPQERSESDSSPDSKAKTRTPLRQRSRSGSSP 1583

Query: 477  KIGLS--LAPRR---GSLPDQKDL-----------------------------RLGSIDL 502
            ++     L+PRR   GS P+ KD                              R GS   
Sbjct: 1584 EVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSK 1643

Query: 503  NWDLKPASSSN----PMDGMDNRTVGGSMRHPPEQTNGVHTPPHVASALAGAVSPGALRR 558
                 P  SS+    P     +RT     R  PE      TPP   S+ +   SP   R+
Sbjct: 1644 GRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRS---SPELTRK 1700

Query: 559  SLEAIKAMSSKGPSASAALSPPLG------SSPGSPGSQSLSS--GETVPIPRPGPAQGD 610
            +  + ++ S+     + + +PP        SSP  P  +S SS    +   PR       
Sbjct: 1701 ARLSRRSRSASSSPETRSRTPPRHRRSPSVSSP-EPAEKSRSSRRRRSASSPRTKTTSRR 1759

Query: 611  GHSLPPIARRL 621
            G S  P  R L
Sbjct: 1760 GRSPSPKPRGL 1770



 Score = 33.5 bits (75), Expect = 0.70
 Identities = 61/261 (23%), Positives = 91/261 (34%), Gaps = 63/261 (24%)

Query: 355  SQAPSGRAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSM-DEAPCVNGRWGTLRP 413
            S  P  ++   P   S  SP  A   ++ P+ R     SP   +    P  +   G+  P
Sbjct: 839  SPHPKVKSGTPPRQGSITSP-QANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPP 897

Query: 414  RAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEG 473
            R +  TP        SP+R           +SP   +  GSS  SP +  S +TP     
Sbjct: 898  RVKSSTPPRQ-----SPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTP----- 947

Query: 474  YDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTV---GGSMRHP 530
                                             + + S +P   +++R +     S    
Sbjct: 948  ---------------------------------RRSRSVSPCSNVESRLLPRYSHSGSSS 974

Query: 531  PEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSP-PLGSSPGS-- 587
            P+      TPP    + +G++SP         +KA +  GPS S + SP P   S  S  
Sbjct: 975  PDTKVKPETPPR--QSHSGSISP------YPKVKAQTPPGPSLSGSKSPCPQEKSKDSLV 1026

Query: 588  ---PGSQSLSSGETVPIPRPG 605
               PGS SL +G     P PG
Sbjct: 1027 QSCPGSLSLCAGVKSSTP-PG 1046


>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
          Length = 1336

 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 44/198 (22%), Positives = 71/198 (35%), Gaps = 37/198 (18%)

Query: 418 QTPSGSR--EGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYD 475
           Q P G++  +G   P    G P  +G    PG+  + G     P+  ++P     P G  
Sbjct: 732 QGPPGTQGMQGPPGPRGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPG-- 789

Query: 476 LKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTN 535
                   PR    P  + + +G               P +       GG + H P++  
Sbjct: 790 --------PRENQGPAPQGMIMGH-------------PPQEMRGPHPPGGLLGHGPQEMR 828

Query: 536 GVHTPPHVASALAGAVSPGALRRSLEAIK----AMSSKGPSASAALSPPLGSSPGSPGSQ 591
           G    P     + G    G++    + ++    + S +GP   +   PP G   G PG Q
Sbjct: 829 G----PQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGPPPQGGMQGPPGPQ 884

Query: 592 SLSSGETVPIPRPGPAQG 609
               G+  P   P P+QG
Sbjct: 885 ----GQQNPARGPHPSQG 898


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 63/288 (21%), Positives = 99/288 (34%), Gaps = 43/288 (14%)

Query: 355 SQAPSGRAPLS-------PSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGR 407
           S+ P+ R P S       P+ N+ P P+S+   A          Q  +R   E     G+
Sbjct: 87  SRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGK 146

Query: 408 WGTLRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPST 467
             T  P+    + +G+R  +  P  G  SP +   S + GT       L  P  +  P  
Sbjct: 147 -ATEAPKRSALS-AGARRDTSGPTPGTPSPAMARRSRAAGTEV----GLPRPAPSARPRP 200

Query: 468 PSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSM 527
           P+  EG          PR       K +   S     +  PA+   P       + GG +
Sbjct: 201 PT--EG----------PR-------KSVSSASEHSTTEPSPAARRRP-------SAGGGL 234

Query: 528 RHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGS 587
           + P  ++      P  + A +G  + G  R         S   P    AL PP  + P  
Sbjct: 235 QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP----SQPKPKGLQALRPPQVTPPRK 290

Query: 588 PGSQSLSSGETVPIPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKPL 635
             + +L    + P+  P P+       PP      H    +  +  PL
Sbjct: 291 DAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPL 338



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 60/281 (21%), Positives = 87/281 (30%), Gaps = 13/281 (4%)

Query: 355 SQAPSGRAPLSPSLNSRPSPISATPPALVPET-REYRSQSPVRSMDEAPCVNGRWGTLRP 413
           ++ P+ RAP    L  RP      PP + P   R   +   V     A    G  G   P
Sbjct: 14  ARTPAARAP--GLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71

Query: 414 RAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEG 473
            +  +       G+ S       P    G  +P         + SP +A   + P     
Sbjct: 72  ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQ 131

Query: 474 YDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQ 533
             L+I       RG   +       S     D    +   P   M  R+           
Sbjct: 132 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE----- 186

Query: 534 TNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSL 593
              V  P    SA     + G  R+S+ +    S+  PS +A   P  G     P S+SL
Sbjct: 187 ---VGLPRPAPSARPRPPTEGP-RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242

Query: 594 SSGETVPIPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKP 634
           SS  T P+  P  +       P          P+ L   +P
Sbjct: 243 SSSAT-PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP 282



 Score = 36.6 bits (83), Expect = 0.083
 Identities = 65/250 (26%), Positives = 93/250 (37%), Gaps = 46/250 (18%)

Query: 363 PLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSG 422
           P S SL+S  +P+S                SP RS   A       GT R  A    P  
Sbjct: 237 PASRSLSSSATPLS----------------SPARSGPSAR------GTPRAPAHPSQPKP 274

Query: 423 S-----REGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTP-SAPEGYDL 476
                 R   ++P R D +P L   S SP       ++L S      P+TP S+     L
Sbjct: 275 KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQL 334

Query: 477 KIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNG 536
              L LAP   S P      L ++       P+ ++  +     +     +  PP   + 
Sbjct: 335 ATPLPLAPPSPSAPPS----LQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP--LSP 388

Query: 537 VHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSG 596
           + TPP  A        P AL  +L  ++A  S  P AS  LSP    SP +P + ++   
Sbjct: 389 LATPPPQA--------PPAL--ALPPLQAPPS--PPASPPLSPLATPSPQAPNALAVHLL 436

Query: 597 ETVPIPRPGP 606
           +    P P P
Sbjct: 437 QAPFSPPPSP 446



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 36/161 (22%), Positives = 58/161 (36%), Gaps = 6/161 (3%)

Query: 311 DAWLLHMHSGPWAWQPLK--VENEEHGAPELW---CHPACRVGQCVVVFSQAPSGRAPLS 365
           DA L   H   W+  P          GAP  W     P    G C +  ++ P    P  
Sbjct: 660 DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAP 719

Query: 366 PSLNSRPSPISATPPALVPETREYRSQSPVRS-MDEAPCVNGRWGTLRPRAQRQTPSGSR 424
            +L+  PSP ++   A         S+SP ++ + E P    +   ++    R     + 
Sbjct: 720 GALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAA 779

Query: 425 EGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISP 465
           EG+   + G       GG      AA+  + L    + +SP
Sbjct: 780 EGAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSP 820


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 43.1 bits (100), Expect = 9e-04
 Identities = 64/283 (22%), Positives = 101/283 (35%), Gaps = 43/283 (15%)

Query: 361 RAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTP 420
           RAP  P+ N+ P P+S+   A          Q  +R   E     G+  T  P+    + 
Sbjct: 93  RAP--PAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGK-ATEAPKRSALS- 148

Query: 421 SGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGL 480
           +G+R  +  P  G  SP +   S + GT       L  P  +  P  P+  EG       
Sbjct: 149 AGARRDTSGPTPGTPSPAMARRSRAAGTEV----GLPRPAPSARPRPPT--EG------- 195

Query: 481 SLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTP 540
              PR       K +   S     +  PA+   P       + GG ++ P  ++      
Sbjct: 196 ---PR-------KSVSSASEHSTTEPSPAARRRP-------SAGGGLQRPASRSLSSSAT 238

Query: 541 PHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVP 600
           P  + A +G  + G  R         S   P    AL PP  + P    + +L    + P
Sbjct: 239 PLSSPARSGPSARGTPRAPAHP----SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 294

Query: 601 IPRPGPAQGDGHSLPPIARRLGHHP-----PQSLNVGKPLYQS 638
           +  P P+     S PP  + L   P       + ++G P  Q+
Sbjct: 295 LATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQA 337



 Score = 34.3 bits (77), Expect = 0.41
 Identities = 74/312 (23%), Positives = 107/312 (34%), Gaps = 63/312 (20%)

Query: 366 PSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQR----QTPS 421
           P+ ++RP P +  P   V    E+ +  P  +    P   G  G  RP ++      TP 
Sbjct: 183 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG--GLQRPASRSLSSSATPL 240

Query: 422 GSREGSLSPARGD-------------GSPILNGGSLSP---GTAAVGGSSLDSPVQAISP 465
            S   S   ARG              G   L    ++P     A   G    SP+   SP
Sbjct: 241 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 300

Query: 466 STPSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGS--IDLNWDLKPASSSNPMDGMDNRTV 523
           S P +P        L   P   + P Q    LGS  +       P+   +P+        
Sbjct: 301 SAPPSPSAPPSLQTLPSPP--ATPPSQATTSLGSPTLQATHSFLPSPPLSPL-ATPPPQA 357

Query: 524 GGSMRHPPEQT--NGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPS--------- 572
             ++  PP Q   +   +PP    A     +P AL  ++  ++A  S  PS         
Sbjct: 358 PPALALPPLQAPPSPPASPPLSPLATPSPQAPNAL--AVHLLQAPFSPPPSPPVQAPFSP 415

Query: 573 -ASAALS---------------PPLGSSPGSPGSQSLSSGETVPIPRPGPAQGDGHSLPP 616
            AS  +S               PPL   P  P S  +S   T P   P P      + PP
Sbjct: 416 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL-----AAPP 470

Query: 617 IARRLGHHPPQS 628
           +  +L   PPQ+
Sbjct: 471 L--QLAKPPPQA 480



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 62/274 (22%), Positives = 98/274 (35%), Gaps = 27/274 (9%)

Query: 355 SQAPSGRAPLSPSLNSRPSPISATP-PALVPETR----EYRSQSPVRSMDEAPCVNGRWG 409
           ++AP   A  + +      P   TP PA+   +R    E     P  S    P   G   
Sbjct: 139 TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRK 198

Query: 410 TLRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPS 469
           ++   ++  T   S      P+ G G       SLS     +   +   P    +P  P+
Sbjct: 199 SVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPA 258

Query: 470 APEGYDLKIGLSLAPRRGSLPDQKDLR--LGSIDLNWDLKPASSSNPMDGMDN--RTVGG 525
            P     K   +L P + + P +KD    LG +  +    P+ S+ P        +T+  
Sbjct: 259 HPSQPKPKGLQALRPPQVT-PPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPS 317

Query: 526 SMRHPPEQTNG-------------VHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPS 572
               PP Q                + +PP    A     +P AL  +L  ++A  S  P 
Sbjct: 318 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL--ALPPLQAPPS--PP 373

Query: 573 ASAALSPPLGSSPGSPGSQSLSSGETVPIPRPGP 606
           AS  LSP    SP +P + ++   +    P P P
Sbjct: 374 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 407



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 36/161 (22%), Positives = 58/161 (36%), Gaps = 6/161 (3%)

Query: 311 DAWLLHMHSGPWAWQPLK--VENEEHGAPELW---CHPACRVGQCVVVFSQAPSGRAPLS 365
           DA L   H   W+  P          GAP  W     P    G C +  ++ P    P  
Sbjct: 621 DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAP 680

Query: 366 PSLNSRPSPISATPPALVPETREYRSQSPVRS-MDEAPCVNGRWGTLRPRAQRQTPSGSR 424
            +L+  PSP ++   A         S+SP ++ + E P    +   ++    R     + 
Sbjct: 681 GALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAA 740

Query: 425 EGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISP 465
           EG+   + G       GG      AA+  + L    + +SP
Sbjct: 741 EGAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSP 781


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 72/291 (24%), Positives = 97/291 (33%), Gaps = 37/291 (12%)

Query: 358 PSGRAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQR 417
           PS  AP  PSL + PSP  ATPP+  P +          S+   P +        P  Q 
Sbjct: 346 PSPSAP--PSLQTLPSP-PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQA 402

Query: 418 QTPSGSREGSLSPARGDGSPILNGG----SLSPGTAAVGGSSLDSPVQAISPSTP----- 468
             PS     SL      GSP L       ++SP       +S   P      S P     
Sbjct: 403 P-PSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPL 461

Query: 469 SAPEGYDLKIGLSLAPRRGSLP-------------------DQKDLRLGSIDLNWDLKPA 509
           S P    L+  LS A    S P                       L +  ++    L P 
Sbjct: 462 SLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPP 521

Query: 510 SSSNPMDGMDNRTVGG--SMRHPPEQTNGVH-TPPHVASALAGAVSPGALRRSLEAIKAM 566
           S   P   +    +    S+  PP QT     T PH+ +    A  P  L+     +   
Sbjct: 522 SLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP--LQAPPSPLTTP 579

Query: 567 SSKGPSASAALSPPLGSSPGSPGSQSLSSGETVPIPRPGPAQGDGHSLPPI 617
             + PS+ A   P    +  SP  Q L S    P+  P P      +LPP+
Sbjct: 580 PPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPL 630



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 60/269 (22%), Positives = 95/269 (35%), Gaps = 43/269 (15%)

Query: 355 SQAPSGRAPLS-------PSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGR 407
           S+ P+ R P S       P+ N+ P P+S+   A          Q  +R   E     G+
Sbjct: 87  SRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGK 146

Query: 408 WGTLRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPST 467
             T  P+    + +G+R  +  P  G  SP +   S + GT       L  P  +  P  
Sbjct: 147 -ATEAPKRSALS-AGARRDTSGPTPGTPSPAMARRSRAAGTEV----GLPRPAPSARPRP 200

Query: 468 PSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSM 527
           P+  EG          PR       K +   S     +  PA+   P       + GG +
Sbjct: 201 PT--EG----------PR-------KSVSSASEHSTTEPSPAARRRP-------SAGGGL 234

Query: 528 RHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGS 587
           + P  ++      P  + A +G  + G  R         S   P    AL PP  + P  
Sbjct: 235 QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP----SQPKPKGLQALRPPQVTPPRK 290

Query: 588 PGSQSLSSGETVPIPRPGPAQGDGHSLPP 616
             + +L    + P+  P P+      +PP
Sbjct: 291 DAAPALGPLSSSPLATPSPSGTKARPVPP 319



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 60/281 (21%), Positives = 87/281 (30%), Gaps = 13/281 (4%)

Query: 355 SQAPSGRAPLSPSLNSRPSPISATPPALVPET-REYRSQSPVRSMDEAPCVNGRWGTLRP 413
           ++ P+ RAP    L  RP      PP + P   R   +   V     A    G  G   P
Sbjct: 14  ARTPAARAP--GLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71

Query: 414 RAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEG 473
            +  +       G+ S       P    G  +P         + SP +A   + P     
Sbjct: 72  ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQ 131

Query: 474 YDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQ 533
             L+I       RG   +       S     D    +   P   M  R+           
Sbjct: 132 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE----- 186

Query: 534 TNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQSL 593
              V  P    SA     + G  R+S+ +    S+  PS +A   P  G     P S+SL
Sbjct: 187 ---VGLPRPAPSARPRPPTEGP-RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242

Query: 594 SSGETVPIPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKP 634
           SS  T P+  P  +       P          P+ L   +P
Sbjct: 243 SSSAT-PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP 282



 Score = 35.0 bits (79), Expect = 0.24
 Identities = 73/317 (23%), Positives = 115/317 (36%), Gaps = 31/317 (9%)

Query: 321  PWAWQPLKVENEEHGAPELWCHPACRVGQCVVVFSQAPSGRAPLSPSLNSRPSPISATPP 380
            P A  PL+V      +P +   P+      V     AP  + P SP  +   SP++  PP
Sbjct: 729  PLAAPPLQVPPSPPASPPM--SPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPP 786

Query: 381  ALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSGSREGS-LSPARGDGSPIL 439
               P      +  P++++   P          P     +PS S   S L+       P+L
Sbjct: 787  QAPPAL----ATPPLQALPSPP-------ASFPGQAPFSPSASLPMSPLATPPPQAPPVL 835

Query: 440  NGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGLSLAPRRGSLPDQK-DLRLG 498
                L    +     +L +P +  +P   ++  G   ++ L+LAP     P +     L 
Sbjct: 836  AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG--PRLTLALAPGPPPPPSRSPSSTLS 893

Query: 499  SIDLNWDLKPASSS-NPMDGMDNRTVGGSMRHPPEQTNGVHTPPHVASALAGAVSPGALR 557
              DL      A+S+   + G D+   GG+   PP          H A+   G   P A R
Sbjct: 894  GPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAE--LAACHPAAWSRGPAPPLAFR 951

Query: 558  RSLEA-IKAMSSKGPSASAALSPPLGSSPGSPGSQSLSSGETVPIPRPGPAQG------- 609
             +  A +    + GP ++  L     +    P S + + G   P P PG + G       
Sbjct: 952  GAPGAPLPWPPATGPGSADGLCTIYETE--GPESATPAPGALDPGPSPGTSGGKAAAGAG 1009

Query: 610  -DGHSLPPIARRLGHHP 625
                S  P   RLG  P
Sbjct: 1010 AGASSRSPKQARLGELP 1026



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 61/297 (20%), Positives = 97/297 (32%), Gaps = 60/297 (20%)

Query: 357 APSGRAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQ 416
           +P  +  LSP+++   SP++  P   +     +  Q+P+ S+            + P  +
Sbjct: 466 SPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSL------------IMPPLE 513

Query: 417 RQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDL 476
            Q+          PA     P+ N  SL+P       + L +P       TP  P    L
Sbjct: 514 TQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTP----HLETPPCPAPCPL 569

Query: 477 KIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNG 536
           +     AP         +             PA +S P+ G+ +  +      PP+    
Sbjct: 570 Q-----APPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPX 624

Query: 537 VHTPPHVAS------------ALAGAVSPGALRRSLEAIKAMSSKGPS----------AS 574
           +  PP  A             A     +P AL  ++  ++A  S  PS          AS
Sbjct: 625 LALPPLQAPPSPPASPPLSPLATPSPQAPNAL--AVHLLQAPFSPPPSPPVQAPFSPPAS 682

Query: 575 AALS---------------PPLGSSPGSPGSQSLSSGETVPIPRPGPAQGDGHSLPP 616
             +S               PPL   P  P S  +S   T P   P P       +PP
Sbjct: 683 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPP 739



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 36/161 (22%), Positives = 58/161 (36%), Gaps = 6/161 (3%)

Query: 311  DAWLLHMHSGPWAWQPLK--VENEEHGAPELW---CHPACRVGQCVVVFSQAPSGRAPLS 365
            DA L   H   W+  P          GAP  W     P    G C +  ++ P    P  
Sbjct: 929  DAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAP 988

Query: 366  PSLNSRPSPISATPPALVPETREYRSQSPVRS-MDEAPCVNGRWGTLRPRAQRQTPSGSR 424
             +L+  PSP ++   A         S+SP ++ + E P    +   ++    R     + 
Sbjct: 989  GALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAA 1048

Query: 425  EGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISP 465
            EG+   + G       GG      AA+  + L    + +SP
Sbjct: 1049 EGAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSP 1089


>gi|72004269 tetra-peptide repeat homeobox [Homo sapiens]
          Length = 411

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 64/272 (23%), Positives = 96/272 (35%), Gaps = 49/272 (18%)

Query: 361 RAPLSPSLNSRPSPI----SATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQ 416
           R P      +R +P+    SA+ P   P      ++  + S+ +A      WG    RAQ
Sbjct: 32  RVPGQRGRGARAAPLVPAASASAPQRGPSGILPAAEPTICSLHQA------WGGPGCRAQ 85

Query: 417 RQTPSGSREGSLSPARGDGSPILNGGSLSPGTAA-------VGGSSLDSPVQAISPSTPS 469
           +  P+     +LSP  G     + G +  PG           G + + SP+ A  P   S
Sbjct: 86  KGIPA-----ALSPGPGPIPAPIPGPAQIPGPLPGSIPGPIPGPAQIPSPIPAPIPGPIS 140

Query: 470 APEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRH 529
            P            P RG +P                 P S   P+ G  +    G    
Sbjct: 141 GPVQIP-------GPFRGPIPG----------------PISGPAPIPGPISGPFSGPNPG 177

Query: 530 PPEQTNGVHTPPHVASALAGAVS---PGALRRSLEAIKAMSSKGPSASAALSPPLGSSPG 586
           P    N    P  ++  + G +S   PG +   +    +  + GP       P  G +PG
Sbjct: 178 PIPGPNPGPIPGPISGPIPGPISVPIPGPIPGPISGPISGPNPGPIPGPIPGPISGPNPG 237

Query: 587 S-PGSQSLSSGETVPIPRPGPAQGDGHSLPPI 617
             PG  S  +   +P P PGP  G G  + PI
Sbjct: 238 PIPGPISGPNPGLIPGPIPGPISGPGPIIGPI 269


>gi|59806361 hypothetical protein LOC387104 [Homo sapiens]
          Length = 947

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 70/279 (25%), Positives = 99/279 (35%), Gaps = 52/279 (18%)

Query: 355 SQAPSGRAPLSPSLNSRPSPISATPPALVPE---TREYRSQSPVRSMDEA---------- 401
           SQ P G A  +P+  +     +AT   L PE    ++ R+QSP R  D +          
Sbjct: 2   SQPPIGGA--APATAAASPAAAATEARLHPEGSSRKQQRAQSPARPRDSSLRQTIAATRS 59

Query: 402 PCVNG------RWGTLRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSS 455
           P   G      R   L+ + Q+   +GSR G  +  RG G        L+P  AA G   
Sbjct: 60  PVGAGTKLNSVRQQQLQQQQQQGNKTGSRTGPPASIRGGGGGAEKATPLAPKGAAPGAVQ 119

Query: 456 LDSPVQAISPSTPSAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPM 515
             +  +A   +T +A           L  RR   P++    L S+       P       
Sbjct: 120 PVAGAEAAPAATLAA-----------LGGRRPGPPEEPPRELESVPSKLGEPPPLGEGGG 168

Query: 516 DGMDNRTVGGSMRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASA 575
            G +    GG      E+  G   PP           P   R   + ++A    G     
Sbjct: 169 GGGEGGGAGGG---SGEREGGAPQPP----------PPRGWRG--KGVRAQQRGGSGGEG 213

Query: 576 ALSPPLGSSPG-SPGSQSLSSGETVPIPRPGPAQGDGHS 613
           A   P  SS G +PG+ S +SG  V     G   G G S
Sbjct: 214 ASPSPSSSSAGKTPGTGSRNSGSGV----AGGGSGGGGS 248


>gi|54860079 nadrin isoform 1 [Homo sapiens]
          Length = 881

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 70/296 (23%), Positives = 106/296 (35%), Gaps = 49/296 (16%)

Query: 357 APSGRAPLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQ 416
           +P+ + PL P+  S   P    PP   P++    S S               GT+     
Sbjct: 520 SPAFQPPLPPTDGSTVVPAGPEPP---PQSSRAESSSG-------------GGTV----- 558

Query: 417 RQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEG-YD 475
              PS +      P+ GDGSP        P +AAV     ++   A   + P A  G + 
Sbjct: 559 ---PSSAGILEQGPSPGDGSP---PKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQ 612

Query: 476 LKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPE--- 532
           L +G    P   + P    LR  ++       P   + P      ++  G+ +HPP    
Sbjct: 613 LSMG---QPHNAAGPSPHTLRR-AVKKPAPAPPKPGNPPPGHPGGQSSSGTSQHPPSLSP 668

Query: 533 ---------QTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGS 583
                     T     PP   SA +   +P     SL  I+A +   P      +P + +
Sbjct: 669 KPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQATPLMHT 728

Query: 584 SP---GSPGSQSLSSGETVPIPRPGPAQ-GDGHSLPPIARRLGHHP-PQSLNVGKP 634
            P   G P   +L S   +  P   P Q     S PP+ ++    P PQ+L  G P
Sbjct: 729 KPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNP 784



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 59/226 (26%), Positives = 86/226 (38%), Gaps = 45/226 (19%)

Query: 410 TLRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPS 469
           TLR   ++  P+  + G+  P    G P   GG  S GT+    S    P    SPS P+
Sbjct: 628 TLRRAVKKPAPAPPKPGNPPP----GHP---GGQSSSGTSQHPPSLSPKPPTR-SPSPPT 679

Query: 470 APEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRH 529
              G          P + S P Q         L+   + +SS +P+   +         H
Sbjct: 680 QHTGQP--------PGQPSAPSQ---------LSAPRRYSSSLSPIQAPN---------H 713

Query: 530 PPEQTNGVHTP-PHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGS-SPGS 587
           PP Q     TP  H      G  +P AL       +   +   + +   +PPLG  +P  
Sbjct: 714 PPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSL 773

Query: 588 PGSQSLSSGE---------TVPIPRPGPAQGDGHSLPPIARRLGHH 624
           P  Q+L+ G          T+P PRP P   +  S+PP  +  G H
Sbjct: 774 PAPQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQPPGVH 819


>gi|54860105 nadrin isoform 2 [Homo sapiens]
          Length = 803

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 59/226 (26%), Positives = 86/226 (38%), Gaps = 45/226 (19%)

Query: 410 TLRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPS 469
           TLR   ++  P+  + G+  P    G P   GG  S GT+    S    P    SPS P+
Sbjct: 550 TLRRAVKKPAPAPPKPGNPPP----GHP---GGQSSSGTSQHPPSLSPKPPTR-SPSPPT 601

Query: 470 APEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRH 529
              G          P + S P Q         L+   + +SS +P+   +         H
Sbjct: 602 QHTGQP--------PGQPSAPSQ---------LSAPRRYSSSLSPIQAPN---------H 635

Query: 530 PPEQTNGVHTP-PHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGS-SPGS 587
           PP Q     TP  H      G  +P AL       +   +   + +   +PPLG  +P  
Sbjct: 636 PPPQPPTQATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSL 695

Query: 588 PGSQSLSSGE---------TVPIPRPGPAQGDGHSLPPIARRLGHH 624
           P  Q+L+ G          T+P PRP P   +  S+PP  +  G H
Sbjct: 696 PAPQTLAGGNPETAQPHAGTLPRPRPVPKPRNRPSVPPPPQPPGVH 741



 Score = 35.0 bits (79), Expect = 0.24
 Identities = 55/243 (22%), Positives = 87/243 (35%), Gaps = 31/243 (12%)

Query: 419 TPSGSREGSLSPARGDGSPILNGGSLS---------PGTAAVGGSSLDSPVQAISPSTPS 469
           T + S  G+L   R     ++ G  +          P +AAV     ++   A   + P 
Sbjct: 468 TGNDSDSGTLERKRPASMAVMEGDLVKKESPPKPKDPVSAAVPAPGRNNSQIASGQNQPQ 527

Query: 470 APEG-YDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMR 528
           A  G + L +G    P   + P    LR  ++       P   + P      ++  G+ +
Sbjct: 528 AAAGSHQLSMG---QPHNAAGPSPHTLRR-AVKKPAPAPPKPGNPPPGHPGGQSSSGTSQ 583

Query: 529 HPPE------------QTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAA 576
           HPP              T     PP   SA +   +P     SL  I+A +   P     
Sbjct: 584 HPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPPPQPPTQ 643

Query: 577 LSPPLGSSP---GSPGSQSLSSGETVPIPRPGPAQ-GDGHSLPPIARRLGHHP-PQSLNV 631
            +P + + P   G P   +L S   +  P   P Q     S PP+ ++    P PQ+L  
Sbjct: 644 ATPLMHTKPNSQGPPNPMALPSEHGLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAG 703

Query: 632 GKP 634
           G P
Sbjct: 704 GNP 706


>gi|72256200 B-cell CLL/lymphoma 9 [Homo sapiens]
          Length = 1426

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 58/253 (22%), Positives = 98/253 (38%), Gaps = 14/253 (5%)

Query: 363  PLSPSLNSRPSPISATPPALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQ---T 419
            PL+PS N  P+ ++  PP      R+    S   S   +P +N        + Q     +
Sbjct: 821  PLNPSSN--PTSLNTAPPVQRGLGRKPLDISVAGSQVHSPGINPLKSPTMHQVQSPMLGS 878

Query: 420  PSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIG 479
            PSG+ +   +P++  G       + S  +  V GS+  SPV   SPS P+   G+     
Sbjct: 879  PSGNLKSPQTPSQLAGMLAGPAAAASIKSPPVLGSAAASPVHLKSPSLPAPSPGWTSSPK 938

Query: 480  LSLAP------RRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRH--PP 531
              L         +  L       LG+++ +    P ++S P       ++  S  +  PP
Sbjct: 939  PPLQSPGIPPNHKAPLTMASPAMLGNVE-SGGPPPPTASQPASVNIPGSLPSSTPYTMPP 997

Query: 532  EQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSPGSPGSQ 591
            E T   +    + S ++    P +     +AIK ++S    +  A SP L S    PG  
Sbjct: 998  EPTLSQNPLSIMMSRMSKFAMPSSTPLYHDAIKTVASSDDDSPPARSPNLPSMNNMPGMG 1057

Query: 592  SLSSGETVPIPRP 604
              +    +  P P
Sbjct: 1058 INTQNPRISGPNP 1070



 Score = 33.1 bits (74), Expect = 0.92
 Identities = 38/131 (29%), Positives = 47/131 (35%), Gaps = 22/131 (16%)

Query: 505 DLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAI- 563
           D KP     P     ++    + R  P       TPP  A A   A  P  L R    + 
Sbjct: 230 DPKPLPQQPPAPANQDQNSSQNTRLQP-------TPPIPAPAPKPAAPPRPLDRESPGVE 282

Query: 564 -KAMSSKGPSASAALSPPLGSSPGS--------PGSQSLSSGETVPIPRPGPAQGDGHSL 614
            K + S G  AS+   PP G+ P S        P SQ  +S    P   P P    G   
Sbjct: 283 NKLIPSVGSPASSTPLPPDGTGPNSTPNNRAVTPVSQGSNSSSADPKAPPPPPVSSGE-- 340

Query: 615 PPIARRLGHHP 625
           PP    LG +P
Sbjct: 341 PP---TLGENP 348



 Score = 31.6 bits (70), Expect = 2.7
 Identities = 90/361 (24%), Positives = 132/361 (36%), Gaps = 63/361 (17%)

Query: 363  PLSPSLNSRPSPISA---TPPALVPETREYRSQSPV--RSMDEAPCV-NGRWGTLRPRAQ 416
            PLS S N  PSP +     PP  VP      S +P+      E P V  GR G  +    
Sbjct: 1085 PLSHS-NQMPSPNAVGPNIPPHGVPMGPGLMSHNPIMGHGSQEPPMVPQGRMGFPQGFPP 1143

Query: 417  RQTPSGSREGSLS-PARGDGSPILNGGSLSPGTAAVGGSS----LDSPVQAISPSTPSAP 471
             Q+P        + P+ G GS    GG   PG   +G  S      +      P  P  P
Sbjct: 1144 VQSPPQQVPFPHNGPSGGQGS--FPGGMGFPGEGPLGRPSNLPQSSADAALCKPGGPGGP 1201

Query: 472  EGYDLKIGLSLAPRRGSLPD-QKDLRLGS-----IDLNWDLKPASSSNPMDGMDNRTVGG 525
            + + + +G S+ P   + PD Q+ +R G+      DL+  +     S  +       V G
Sbjct: 1202 DSFTV-LGNSM-PSVFTDPDLQEVIRPGATGIPEFDLSRIIPSEKPSQTLQYFPRGEVPG 1259

Query: 526  SMRHPPEQTNGVHTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPPLGSSP 585
                  +Q  G   P    S + G +   A R  L A+  M   GP  +  +  PLG++P
Sbjct: 1260 R-----KQPQG---PGPGFSHMQGMMGEQAPRMGL-ALPGMGGPGPVGTPDI--PLGTAP 1308

Query: 586  GSPGSQSLSSGETVPIPRPGPAQGDGHSLPPIARRLGHHPPQSLNVGKPLYQSMNCKPMQ 645
              PG            P   PA      + P  R +   P QS   G+P   S     + 
Sbjct: 1309 SMPGHN----------PMRPPAFLQQGMMGPHHRMMS--PAQSTMPGQPTLMSNPAAAVG 1356

Query: 646  MYVLDIKDTKEKGRVKWKVFNSSSVVGPPETSLHTVVQGRGELIIFGGLMDKKQNVKYYP 705
            M  +  KD    G     ++     VG P           G ++   G+M  +QN+   P
Sbjct: 1357 M--IPGKDRGPAG-----LYTHPGPVGSP-----------GMMMSMQGMMGPQQNIMIPP 1398

Query: 706  K 706
            +
Sbjct: 1399 Q 1399


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 41.6 bits (96), Expect = 0.003
 Identities = 77/280 (27%), Positives = 97/280 (34%), Gaps = 43/280 (15%)

Query: 365 SPSLNSRPSPISATPPALVPETREYRSQSPV-----RSMDEAPCVNGRWGTLRPRAQRQT 419
           SPS ++ PSP         P  R  RS SP      RS   AP    R  T  P  +R+T
Sbjct: 524 SPSRSASPSPRKRQKETS-PRGRRRRSPSPPPTRRRRSPSPAPPPRRR-RTPTPPPRRRT 581

Query: 420 PSGS-REGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTP---------- 468
           PS   R  S SP R    PI    S SP       S    P +  SPS P          
Sbjct: 582 PSPPPRRRSPSPRRYS-PPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPP 640

Query: 469 ----SAPEGYDLKIGLSLAPRRGSLPDQKDLRLGSIDLNWDLKPA-------SSSNPMDG 517
               S+P        LS   R+GS P +      S   N    P+       +SS+P   
Sbjct: 641 PKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPV 700

Query: 518 MDNRTVGGSMRHPPEQTNGV-----HTPPHVASALAGAVSPGALRRSLEAIKAMSSKGPS 572
               +     R  P  +         TP       A + SP ++RR      + S  G  
Sbjct: 701 RRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRR---VSSSRSVSGSP 757

Query: 573 ASAALSPPLGSSPGSPGSQSLSSGETVPI-----PRPGPA 607
             AA  PP   SP    S S +    VP+     P P P+
Sbjct: 758 EPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPS 797



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 65/270 (24%), Positives = 89/270 (32%), Gaps = 63/270 (23%)

Query: 366 PSLNSRPSPISATPP-ALVPETREYRSQSPVRSMDEAPCVNGRWGTLRPRAQRQTPSGSR 424
           PS   RPSP   TPP  + P  R  RS+SPVR    +        +L   +   + S SR
Sbjct: 315 PSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSS------ASLSGSSSSSSSSRSR 368

Query: 425 EGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSAPEGYDLKIGLSLAP 484
                P +   SP      LSP        S   P +   PS P+ P             
Sbjct: 369 SPPKKPPKRTSSPPRKTRRLSP--------SASPPRRRHRPSPPATP------------- 407

Query: 485 RRGSLPDQKDLRLGSIDLNWDLKPASSSNPMDGMDNRTVGGSMRHPPEQTNGVHTPPHVA 544
                                  P +  +P     NRT    +   P +T+G  T  H  
Sbjct: 408 ----------------------PPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVT-KHKG 444

Query: 545 SALAGAVSPGALRRSLEAIKAMSSKGPSASAALSPP------LGSSPGSPGSQSLSSGET 598
           +    + SP    R +E  ++   KG   +AA S          +   S  S S SS E 
Sbjct: 445 TEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSED 504

Query: 599 VPIPRPGPAQGDGHSLPPIARRLGHHPPQS 628
               R     G+      + RR  H P +S
Sbjct: 505 ERPKRSHVKNGE------VGRRRRHSPSRS 528



 Score = 32.7 bits (73), Expect = 1.2
 Identities = 36/121 (29%), Positives = 47/121 (38%), Gaps = 7/121 (5%)

Query: 355 SQAPSGRAPLSPSLNSR--PSPISATPP--ALVPETREYRSQSPVRSMDEAPCVNGRWGT 410
           S + S R   SP  N R  PSP    P   +  P  R   S SP R    +P        
Sbjct: 665 SPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRV 724

Query: 411 LRPRAQRQTPSGSREGSLSPARGDGSPILNGGSLSPGTAAVGGSSLDSPVQAISPSTPSA 470
            R    ++    +     S  R   S  ++G   SP  AA    +  SPVQ+ SPST  +
Sbjct: 725 SRTPEPKKIKKAASPSPQSVRRVSSSRSVSG---SPEPAAKKPPAPPSPVQSQSPSTNWS 781

Query: 471 P 471
           P
Sbjct: 782 P 782


>gi|158508542 kelch-like 33 [Homo sapiens]
          Length = 453

 Score = 41.2 bits (95), Expect = 0.003
 Identities = 50/221 (22%), Positives = 82/221 (37%), Gaps = 33/221 (14%)

Query: 86  AHQCYHGFMKAVQEGNIQWESRTYPYPGTPITQRFSHSACYYDANQSMYVFGGCTQSSCN 145
           A +C  G ++ V+ G +         P  P   RF H A    A   +YV GG    S +
Sbjct: 157 AFRCGVGLVRTVEWGQL---------PALPAPGRFRHGAASL-AGSELYVCGGQDFYSHS 206

Query: 146 AAFNDLWRLDLNSKEW--IRPLASGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQP 203
                  R + + ++W  + PL+       ++  +LV     L   GG            
Sbjct: 207 NTLASTLRWEPSQEDWEEMAPLSQA-----RSLFSLVALDGKLYALGG---------RHN 252

Query: 204 ERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVL 263
           +   D + TY+P  N W        P P   H++ +++ ++ V GG  G+ Q    +   
Sbjct: 253 DVALDSVETYNPELNVWRPAPAL--PAPCFAHAAAILEGQLYVSGGCGGTGQYLASLMHY 310

Query: 264 DLEQWAWSKP-NISGPSPHPRGGQSQIVIDDATILILGGCG 303
           D +     KP     P   PR G     +    + + GG G
Sbjct: 311 DPK---LEKPGTFLSPMGVPRAGHVMAAL-GGRLYVAGGLG 347



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 30/108 (27%), Positives = 48/108 (44%), Gaps = 15/108 (13%)

Query: 133 MYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASGSYPSPKAGATLVVYKDLLVLFGGW 192
           +YV GG  ++    +F + + L  +S   + PL     PSP  GA   V +  L++ GG+
Sbjct: 340 LYVAGGLGETEDLLSF-EAYELRTDSWTHLAPL-----PSPHVGAASAVLQGELLVLGGY 393

Query: 193 TRPSPYPLHQPERFFDEIHTYSPSKNWWNCIVTTHGPPPMAGHSSCVI 240
           +       H+       IH Y P    W C+ T   P P A   +C++
Sbjct: 394 S-------HRTYALSHLIHAYCPGLGRWLCLGTL--PRPRAEMPACIL 432


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.132    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,832,405
Number of Sequences: 37866
Number of extensions: 2100080
Number of successful extensions: 9164
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 63
Number of HSP's successfully gapped in prelim test: 497
Number of HSP's that attempted gapping in prelim test: 7940
Number of HSP's gapped (non-prelim): 1560
length of query: 717
length of database: 18,247,518
effective HSP length: 110
effective length of query: 607
effective length of database: 14,082,258
effective search space: 8547930606
effective search space used: 8547930606
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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