Guide to the Human Genome
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Search of human proteins with 61743954

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|61743954 AHNAK nucleoprotein isoform 1 [Homo sapiens]
         (5890 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|61743954 AHNAK nucleoprotein isoform 1 [Homo sapiens]             1.200e+04   0.0  
gi|156766050 AHNAK nucleoprotein 2 [Homo sapiens]                    1613   0.0  
gi|116686120 periaxin isoform 2 [Homo sapiens]                        266   6e-70
gi|55769541 AHNAK nucleoprotein isoform 2 [Homo sapiens]              234   2e-60
gi|110349719 titin isoform N2-A [Homo sapiens]                         94   3e-18
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...    79   1e-13
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...    79   1e-13
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...    79   1e-13
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]     72   1e-11
gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]        66   9e-10
gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]        66   9e-10
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          66   1e-09
gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo ...    66   1e-09
gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo s...    66   1e-09
gi|154759255 collagen, type XXVIII precursor [Homo sapiens]            65   2e-09
gi|16554449 zonadhesin isoform 3 [Homo sapiens]                        61   4e-08
gi|27881494 zonadhesin isoform 6 [Homo sapiens]                        61   4e-08
gi|169205253 PREDICTED: hypothetical protein [Homo sapiens]            60   5e-08
gi|224589132 hypothetical protein LOC100132406 [Homo sapiens]          58   2e-07
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       58   2e-07
gi|126352608 elastin isoform e precursor [Homo sapiens]                57   5e-07
gi|126352700 elastin isoform b precursor [Homo sapiens]                57   5e-07
gi|126352440 elastin isoform a precursor [Homo sapiens]                57   7e-07
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...    57   7e-07
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...    57   7e-07
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...    57   7e-07
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s...    57   7e-07
gi|126352322 elastin isoform c precursor [Homo sapiens]                56   9e-07
gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens]         56   9e-07
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]    56   1e-06

>gi|61743954 AHNAK nucleoprotein isoform 1 [Homo sapiens]
          Length = 5890

 Score = 1.200e+04 bits (31150), Expect = 0.0
 Identities = 5890/5890 (100%), Positives = 5890/5890 (100%)

Query: 1    MEKEETTRELLLPNWQGSGSHGLTIAQRDDGVFVQEVTQNSPAARTGVVKEGDQIVGATI 60
            MEKEETTRELLLPNWQGSGSHGLTIAQRDDGVFVQEVTQNSPAARTGVVKEGDQIVGATI
Sbjct: 1    MEKEETTRELLLPNWQGSGSHGLTIAQRDDGVFVQEVTQNSPAARTGVVKEGDQIVGATI 60

Query: 61   YFDNLQSGEVTQLLNTMGHHTVGLKLHRKGDRSPEPGQTWTREVFSSCSSEVVLSGDDEE 120
            YFDNLQSGEVTQLLNTMGHHTVGLKLHRKGDRSPEPGQTWTREVFSSCSSEVVLSGDDEE
Sbjct: 61   YFDNLQSGEVTQLLNTMGHHTVGLKLHRKGDRSPEPGQTWTREVFSSCSSEVVLSGDDEE 120

Query: 121  YQRIYTTKIKPRLKSEDGVEGDLGETQSRTITVTRRVTAYTVDVTGREGAKDIDISSPEF 180
            YQRIYTTKIKPRLKSEDGVEGDLGETQSRTITVTRRVTAYTVDVTGREGAKDIDISSPEF
Sbjct: 121  YQRIYTTKIKPRLKSEDGVEGDLGETQSRTITVTRRVTAYTVDVTGREGAKDIDISSPEF 180

Query: 181  KIKIPRHELTEISNVDVETQSGKTVIRLPSGSGAASPTGSAVDIRAGAISASGPELQGAG 240
            KIKIPRHELTEISNVDVETQSGKTVIRLPSGSGAASPTGSAVDIRAGAISASGPELQGAG
Sbjct: 181  KIKIPRHELTEISNVDVETQSGKTVIRLPSGSGAASPTGSAVDIRAGAISASGPELQGAG 240

Query: 241  HSKLQVTMPGIKVGGSGVNVNAKGLDLGGRGGVQVPAVDISSSLGGRAVEVQGPSLESGD 300
            HSKLQVTMPGIKVGGSGVNVNAKGLDLGGRGGVQVPAVDISSSLGGRAVEVQGPSLESGD
Sbjct: 241  HSKLQVTMPGIKVGGSGVNVNAKGLDLGGRGGVQVPAVDISSSLGGRAVEVQGPSLESGD 300

Query: 301  HGKIKFPTMKVPKFGVSTGREGQTPKAGLRVSAPEVSVGHKGGKPGLTIQAPQLEVSVPS 360
            HGKIKFPTMKVPKFGVSTGREGQTPKAGLRVSAPEVSVGHKGGKPGLTIQAPQLEVSVPS
Sbjct: 301  HGKIKFPTMKVPKFGVSTGREGQTPKAGLRVSAPEVSVGHKGGKPGLTIQAPQLEVSVPS 360

Query: 361  ANIEGLEGKLKGPQITGPSLEGDLGLKGAKPQGHIGVDASAPQIGGSITGPSVEVQAPDI 420
            ANIEGLEGKLKGPQITGPSLEGDLGLKGAKPQGHIGVDASAPQIGGSITGPSVEVQAPDI
Sbjct: 361  ANIEGLEGKLKGPQITGPSLEGDLGLKGAKPQGHIGVDASAPQIGGSITGPSVEVQAPDI 420

Query: 421  DVQGPGSKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLE 480
            DVQGPGSKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLE
Sbjct: 421  DVQGPGSKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLE 480

Query: 481  GKMKGTKVKTPEMIIQKPKISMQDVDLSLGSPKLKGDIKVSAPGVQGDVKGPQVALKGSR 540
            GKMKGTKVKTPEMIIQKPKISMQDVDLSLGSPKLKGDIKVSAPGVQGDVKGPQVALKGSR
Sbjct: 481  GKMKGTKVKTPEMIIQKPKISMQDVDLSLGSPKLKGDIKVSAPGVQGDVKGPQVALKGSR 540

Query: 541  VDIETPNLEGTLTGPRLGSPSGKTGTCRISMSEVDLNVAAPKVKGGVDVTLPRVEGKVKV 600
            VDIETPNLEGTLTGPRLGSPSGKTGTCRISMSEVDLNVAAPKVKGGVDVTLPRVEGKVKV
Sbjct: 541  VDIETPNLEGTLTGPRLGSPSGKTGTCRISMSEVDLNVAAPKVKGGVDVTLPRVEGKVKV 600

Query: 601  PEVDVRGPKVDVSAPDVEAHGPEWNLKMPKMKMPTFSTPGAKGEGPDVHMTLPKGDISIS 660
            PEVDVRGPKVDVSAPDVEAHGPEWNLKMPKMKMPTFSTPGAKGEGPDVHMTLPKGDISIS
Sbjct: 601  PEVDVRGPKVDVSAPDVEAHGPEWNLKMPKMKMPTFSTPGAKGEGPDVHMTLPKGDISIS 660

Query: 661  GPKVNVEAPDVNLEGLGGKLKGPDVKLPDMSVKTPKISMPDVDLHVKGTKVKGEYDVTVP 720
            GPKVNVEAPDVNLEGLGGKLKGPDVKLPDMSVKTPKISMPDVDLHVKGTKVKGEYDVTVP
Sbjct: 661  GPKVNVEAPDVNLEGLGGKLKGPDVKLPDMSVKTPKISMPDVDLHVKGTKVKGEYDVTVP 720

Query: 721  KLEGELKGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSVPGFKAEGPEVDVNLPKADVDI 780
            KLEGELKGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSVPGFKAEGPEVDVNLPKADVDI
Sbjct: 721  KLEGELKGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSVPGFKAEGPEVDVNLPKADVDI 780

Query: 781  SGPKIDVTAPDVSIEEPEGKLKGPKFKMPEMNIKVPKISMPDVDLHLKGPNVKGEYDVTM 840
            SGPKIDVTAPDVSIEEPEGKLKGPKFKMPEMNIKVPKISMPDVDLHLKGPNVKGEYDVTM
Sbjct: 781  SGPKIDVTAPDVSIEEPEGKLKGPKFKMPEMNIKVPKISMPDVDLHLKGPNVKGEYDVTM 840

Query: 841  PKVESEIKVPDVELKSAKMDIDVPDVEVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVN 900
            PKVESEIKVPDVELKSAKMDIDVPDVEVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVN
Sbjct: 841  PKVESEIKVPDVELKSAKMDIDVPDVEVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVN 900

Query: 901  LPKADVDISGPKVGVEVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGPKV 960
            LPKADVDISGPKVGVEVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGPKV
Sbjct: 901  LPKADVDISGPKVGVEVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGPKV 960

Query: 961  KGEYDMTVPKLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGPEFDV 1020
            KGEYDMTVPKLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGPEFDV
Sbjct: 961  KGEYDMTVPKLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGPEFDV 1020

Query: 1021 NLSKANVDISAPKVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKGPK 1080
            NLSKANVDISAPKVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKGPK
Sbjct: 1021 NLSKANVDISAPKVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKGPK 1080

Query: 1081 MKGNVDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLK 1140
            MKGNVDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLK
Sbjct: 1081 MKGNVDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLK 1140

Query: 1141 GEGPEVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDV 1200
            GEGPEVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDV
Sbjct: 1141 GEGPEVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDV 1200

Query: 1201 DLHLKGPKVKGDVDVSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMP 1260
            DLHLKGPKVKGDVDVSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMP
Sbjct: 1201 DLHLKGPKVKGDVDVSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMP 1260

Query: 1261 KFSMPGFKGEGREVDVNLPKADIDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKA 1320
            KFSMPGFKGEGREVDVNLPKADIDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKA
Sbjct: 1261 KFSMPGFKGEGREVDVNLPKADIDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKA 1320

Query: 1321 PKISMPDVDLNLKGPKLKGDVDVSLPEVEGEMKVPDVDIKGPKVDISAPDVDVHGPDWHL 1380
            PKISMPDVDLNLKGPKLKGDVDVSLPEVEGEMKVPDVDIKGPKVDISAPDVDVHGPDWHL
Sbjct: 1321 PKISMPDVDLNLKGPKLKGDVDVSLPEVEGEMKVPDVDIKGPKVDISAPDVDVHGPDWHL 1380

Query: 1381 KMPKVKMPKFSMPGFKGEGPEVDVKLPKADVDVSGPKMDAEVPDVNIEGPDAKLKGPKFK 1440
            KMPKVKMPKFSMPGFKGEGPEVDVKLPKADVDVSGPKMDAEVPDVNIEGPDAKLKGPKFK
Sbjct: 1381 KMPKVKMPKFSMPGFKGEGPEVDVKLPKADVDVSGPKMDAEVPDVNIEGPDAKLKGPKFK 1440

Query: 1441 MPEMSIKPQKISIPDVGLHLKGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKVDINAPDVE 1500
            MPEMSIKPQKISIPDVGLHLKGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKVDINAPDVE
Sbjct: 1441 MPEMSIKPQKISIPDVGLHLKGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKVDINAPDVE 1500

Query: 1501 VHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPDVNLEAPEG 1560
            VHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPDVNLEAPEG
Sbjct: 1501 VHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPDVNLEAPEG 1560

Query: 1561 KLKGPKFKMPSMNIQTHKISMPDVGLNLKAPKLKTDVDVSLPKVEGDLKGPEIDVKAPKM 1620
            KLKGPKFKMPSMNIQTHKISMPDVGLNLKAPKLKTDVDVSLPKVEGDLKGPEIDVKAPKM
Sbjct: 1561 KLKGPKFKMPSMNIQTHKISMPDVGLNLKAPKLKTDVDVSLPKVEGDLKGPEIDVKAPKM 1620

Query: 1621 DVNVGDIDIEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDMDVSVPKVEG 1680
            DVNVGDIDIEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDMDVSVPKVEG
Sbjct: 1621 DVNVGDIDIEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDMDVSVPKVEG 1680

Query: 1681 EMKVPDVDIKGPKVDIDAPDVEVHDPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKAD 1740
            EMKVPDVDIKGPKVDIDAPDVEVHDPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKAD
Sbjct: 1681 EMKVPDVDIKGPKVDIDAPDVEVHDPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKAD 1740

Query: 1741 IDVSGPSVDTDAPDLDIEGPEGKLKGSKFKMPKLNIKAPKVSMPDVDLNLKGPKLKGEID 1800
            IDVSGPSVDTDAPDLDIEGPEGKLKGSKFKMPKLNIKAPKVSMPDVDLNLKGPKLKGEID
Sbjct: 1741 IDVSGPSVDTDAPDLDIEGPEGKLKGSKFKMPKLNIKAPKVSMPDVDLNLKGPKLKGEID 1800

Query: 1801 ASVPELEGDLRGPQVDVKGPFVEAEVPDVDLECPDAKLKGPKFKMPEMHFKAPKISMPDV 1860
            ASVPELEGDLRGPQVDVKGPFVEAEVPDVDLECPDAKLKGPKFKMPEMHFKAPKISMPDV
Sbjct: 1801 ASVPELEGDLRGPQVDVKGPFVEAEVPDVDLECPDAKLKGPKFKMPEMHFKAPKISMPDV 1860

Query: 1861 DLHLKGPKVKGDADVSVPKLEGDLTGPSVGVEVPDVELECPDAKLKGPKFKMPDMHFKAP 1920
            DLHLKGPKVKGDADVSVPKLEGDLTGPSVGVEVPDVELECPDAKLKGPKFKMPDMHFKAP
Sbjct: 1861 DLHLKGPKVKGDADVSVPKLEGDLTGPSVGVEVPDVELECPDAKLKGPKFKMPDMHFKAP 1920

Query: 1921 KISMPDVDLHLKGPKVKGDVDVSVPKLEGDLTGPSVGVEVPDVELECPDAKLKGPKFKMP 1980
            KISMPDVDLHLKGPKVKGDVDVSVPKLEGDLTGPSVGVEVPDVELECPDAKLKGPKFKMP
Sbjct: 1921 KISMPDVDLHLKGPKVKGDVDVSVPKLEGDLTGPSVGVEVPDVELECPDAKLKGPKFKMP 1980

Query: 1981 EMHFKTPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKMDIDAPDVDVH 2040
            EMHFKTPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKMDIDAPDVDVH
Sbjct: 1981 EMHFKTPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKMDIDAPDVDVH 2040

Query: 2041 GPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVVVSGPKVDVEVPDVSLEGPEGKL 2100
            GPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVVVSGPKVDVEVPDVSLEGPEGKL
Sbjct: 2041 GPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVVVSGPKVDVEVPDVSLEGPEGKL 2100

Query: 2101 KGPKLKMPEMHFKAPKISMPDVDLHLKGPKVKGDVDVSLPKLEGDLTGPSVDVEVPDVEL 2160
            KGPKLKMPEMHFKAPKISMPDVDLHLKGPKVKGDVDVSLPKLEGDLTGPSVDVEVPDVEL
Sbjct: 2101 KGPKLKMPEMHFKAPKISMPDVDLHLKGPKVKGDVDVSLPKLEGDLTGPSVDVEVPDVEL 2160

Query: 2161 ECPDAKLKGPKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMDVSVPKVEGEMKVPDVDI 2220
            ECPDAKLKGPKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMDVSVPKVEGEMKVPDVDI
Sbjct: 2161 ECPDAKLKGPKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMDVSVPKVEGEMKVPDVDI 2220

Query: 2221 RGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKGEGPEVDVNLPKADVDVSGPKVD 2280
            RGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKGEGPEVDVNLPKADVDVSGPKVD
Sbjct: 2221 RGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKGEGPEVDVNLPKADVDVSGPKVD 2280

Query: 2281 VEVPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVDVSAPKLEGE 2340
            VEVPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVDVSAPKLEGE
Sbjct: 2281 VEVPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVDVSAPKLEGE 2340

Query: 2341 LKGPELDVKGPKLDADMPEVAVEGPNGKWKTPKFKMPDMHFKAPKISMPDLDLHLKSPKA 2400
            LKGPELDVKGPKLDADMPEVAVEGPNGKWKTPKFKMPDMHFKAPKISMPDLDLHLKSPKA
Sbjct: 2341 LKGPELDVKGPKLDADMPEVAVEGPNGKWKTPKFKMPDMHFKAPKISMPDLDLHLKSPKA 2400

Query: 2401 KGEVDVDVPKLEGDLKGPHVDVSGPDIDIEGPEGKLKGPKFKMPDMHFKAPNISMPDVDL 2460
            KGEVDVDVPKLEGDLKGPHVDVSGPDIDIEGPEGKLKGPKFKMPDMHFKAPNISMPDVDL
Sbjct: 2401 KGEVDVDVPKLEGDLKGPHVDVSGPDIDIEGPEGKLKGPKFKMPDMHFKAPNISMPDVDL 2460

Query: 2461 NLKGPKIKGDVDVSVPEVEGKLEVPDMNIRGPKVDVNAPDVQAPDWHLKMPKMKMPKFSM 2520
            NLKGPKIKGDVDVSVPEVEGKLEVPDMNIRGPKVDVNAPDVQAPDWHLKMPKMKMPKFSM
Sbjct: 2461 NLKGPKIKGDVDVSVPEVEGKLEVPDMNIRGPKVDVNAPDVQAPDWHLKMPKMKMPKFSM 2520

Query: 2521 PGFKAEGPEVDVNLPKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPKIS 2580
            PGFKAEGPEVDVNLPKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPKIS
Sbjct: 2521 PGFKAEGPEVDVNLPKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPKIS 2580

Query: 2581 MPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKMPK 2640
            MPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKMPK
Sbjct: 2581 MPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKMPK 2640

Query: 2641 VKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKLKGPKFKMPEM 2700
            VKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKLKGPKFKMPEM
Sbjct: 2641 VKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKLKGPKFKMPEM 2700

Query: 2701 NIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGP 2760
            NIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGP
Sbjct: 2701 NIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGP 2760

Query: 2761 DWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGPEGKWKS 2820
            DWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGPEGKWKS
Sbjct: 2761 DWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGPEGKWKS 2820

Query: 2821 PKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPEVDLKGPKVDIDV 2880
            PKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPEVDLKGPKVDIDV
Sbjct: 2821 PKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPEVDLKGPKVDIDV 2880

Query: 2881 PDVNVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDVSGPKVDVEGPDVNIE 2940
            PDVNVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDVSGPKVDVEGPDVNIE
Sbjct: 2881 PDVNVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDVSGPKVDVEGPDVNIE 2940

Query: 2941 GPEGKLKGPKFKMPEMNIKAPKIPMPDFDLHLKGPKVKGDVDISLPKVEGDLKGPEVDIR 3000
            GPEGKLKGPKFKMPEMNIKAPKIPMPDFDLHLKGPKVKGDVDISLPKVEGDLKGPEVDIR
Sbjct: 2941 GPEGKLKGPKFKMPEMNIKAPKIPMPDFDLHLKGPKVKGDVDISLPKVEGDLKGPEVDIR 3000

Query: 3001 GPQVDIDVPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDI 3060
            GPQVDIDVPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDI
Sbjct: 3001 GPQVDIDVPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDI 3060

Query: 3061 DVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDM 3120
            DVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDM
Sbjct: 3061 DVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDM 3120

Query: 3121 KVPDVDIKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISMPGFKGEGPEVDVNLPKADLD 3180
            KVPDVDIKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISMPGFKGEGPEVDVNLPKADLD
Sbjct: 3121 KVPDVDIKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISMPGFKGEGPEVDVNLPKADLD 3180

Query: 3181 VSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDLDLNLKGPKMKGEVDVS 3240
            VSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDLDLNLKGPKMKGEVDVS
Sbjct: 3181 VSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDLDLNLKGPKMKGEVDVS 3240

Query: 3241 LANVEGDLKGPALDIKGPKIDVDAPDIDIHGPDAKLKGPKLKMPDMHVNMPKISMPEIDL 3300
            LANVEGDLKGPALDIKGPKIDVDAPDIDIHGPDAKLKGPKLKMPDMHVNMPKISMPEIDL
Sbjct: 3241 LANVEGDLKGPALDIKGPKIDVDAPDIDIHGPDAKLKGPKLKMPDMHVNMPKISMPEIDL 3300

Query: 3301 NLKGSKLKGDVDVSGPKLEGDIKAPSLDIKGPEVDVSGPKLNIEGKSKKSRFKLPKFNFS 3360
            NLKGSKLKGDVDVSGPKLEGDIKAPSLDIKGPEVDVSGPKLNIEGKSKKSRFKLPKFNFS
Sbjct: 3301 NLKGSKLKGDVDVSGPKLEGDIKAPSLDIKGPEVDVSGPKLNIEGKSKKSRFKLPKFNFS 3360

Query: 3361 GSKVQTPEVDVKGKKPDIDITGPKVDINAPDVEVQGKVKGSKFKMPFLSISSPKVSMPDV 3420
            GSKVQTPEVDVKGKKPDIDITGPKVDINAPDVEVQGKVKGSKFKMPFLSISSPKVSMPDV
Sbjct: 3361 GSKVQTPEVDVKGKKPDIDITGPKVDINAPDVEVQGKVKGSKFKMPFLSISSPKVSMPDV 3420

Query: 3421 ELNLKSPKVKGDLDIAGPNLEGDFKGPKVDIKAPEVNLNAPDVDVHGPDWNLKMPKMKMP 3480
            ELNLKSPKVKGDLDIAGPNLEGDFKGPKVDIKAPEVNLNAPDVDVHGPDWNLKMPKMKMP
Sbjct: 3421 ELNLKSPKVKGDLDIAGPNLEGDFKGPKVDIKAPEVNLNAPDVDVHGPDWNLKMPKMKMP 3480

Query: 3481 KFSVSGLKAEGPDVAVDLPKGDINIEGPSMNIEGPDLNVEGPEGGLKGPKFKMPDMNIKA 3540
            KFSVSGLKAEGPDVAVDLPKGDINIEGPSMNIEGPDLNVEGPEGGLKGPKFKMPDMNIKA
Sbjct: 3481 KFSVSGLKAEGPDVAVDLPKGDINIEGPSMNIEGPDLNVEGPEGGLKGPKFKMPDMNIKA 3540

Query: 3541 PKISMPDIDLNLKGPKVKGDVDISLPKLEGDLKGPEVDIKGPKVDINAPDVDVHGPDWHL 3600
            PKISMPDIDLNLKGPKVKGDVDISLPKLEGDLKGPEVDIKGPKVDINAPDVDVHGPDWHL
Sbjct: 3541 PKISMPDIDLNLKGPKVKGDVDISLPKLEGDLKGPEVDIKGPKVDINAPDVDVHGPDWHL 3600

Query: 3601 KMPKVKMPKFSMPGFKGEGPEVDVTLPKADIDISGPNVDVDVPDVNIEGPDAKLKGPKFK 3660
            KMPKVKMPKFSMPGFKGEGPEVDVTLPKADIDISGPNVDVDVPDVNIEGPDAKLKGPKFK
Sbjct: 3601 KMPKVKMPKFSMPGFKGEGPEVDVTLPKADIDISGPNVDVDVPDVNIEGPDAKLKGPKFK 3660

Query: 3661 MPEMNIKAPKISMPDFDLNLKGPKMKGDVVVSLPKVEGDLKGPEVDIKGPKVDIDTPDIN 3720
            MPEMNIKAPKISMPDFDLNLKGPKMKGDVVVSLPKVEGDLKGPEVDIKGPKVDIDTPDIN
Sbjct: 3661 MPEMNIKAPKISMPDFDLNLKGPKMKGDVVVSLPKVEGDLKGPEVDIKGPKVDIDTPDIN 3720

Query: 3721 IEGSEGKFKGPKFKIPEMHLKAPKISMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPEVD 3780
            IEGSEGKFKGPKFKIPEMHLKAPKISMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPEVD
Sbjct: 3721 IEGSEGKFKGPKFKIPEMHLKAPKISMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPEVD 3780

Query: 3781 IKGPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKV 3840
            IKGPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKV
Sbjct: 3781 IKGPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKV 3840

Query: 3841 DIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEG 3900
            DIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEG
Sbjct: 3841 DIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEG 3900

Query: 3901 DMQVPDLDIKGPKVDINAPDVDVRGPDWHLKMPKIKMPKISMPGFKGEGPEVDVNLPKAD 3960
            DMQVPDLDIKGPKVDINAPDVDVRGPDWHLKMPKIKMPKISMPGFKGEGPEVDVNLPKAD
Sbjct: 3901 DMQVPDLDIKGPKVDINAPDVDVRGPDWHLKMPKIKMPKISMPGFKGEGPEVDVNLPKAD 3960

Query: 3961 LDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVD 4020
            LDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVD
Sbjct: 3961 LDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVD 4020

Query: 4021 VSLPKMEGDLKAPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEV 4080
            VSLPKMEGDLKAPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEV
Sbjct: 4021 VSLPKMEGDLKAPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEV 4080

Query: 4081 DVNLPKADIDVSGPKVDIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKG 4140
            DVNLPKADIDVSGPKVDIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKG
Sbjct: 4081 DVNLPKADIDVSGPKVDIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKG 4140

Query: 4141 PKMKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPG 4200
            PKMKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPG
Sbjct: 4141 PKMKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPG 4200

Query: 4201 FKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP 4260
            FKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP
Sbjct: 4201 FKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP 4260

Query: 4261 DFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVK 4320
            DFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVK
Sbjct: 4261 DFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVK 4320

Query: 4321 MPKFSMPGFKGEGPDVDVTLPKADIEISGPKVDIDAPDVSIEGPDAKLKGPKFKMPEMNI 4380
            MPKFSMPGFKGEGPDVDVTLPKADIEISGPKVDIDAPDVSIEGPDAKLKGPKFKMPEMNI
Sbjct: 4321 MPKFSMPGFKGEGPDVDVTLPKADIEISGPKVDIDAPDVSIEGPDAKLKGPKFKMPEMNI 4380

Query: 4381 KAPKISMPDIDFNLKGPKVKGDVDVSLPKVEGDLKGPEIDIKGPSLDIDTPDVNIEGPEG 4440
            KAPKISMPDIDFNLKGPKVKGDVDVSLPKVEGDLKGPEIDIKGPSLDIDTPDVNIEGPEG
Sbjct: 4381 KAPKISMPDIDFNLKGPKVKGDVDVSLPKVEGDLKGPEIDIKGPSLDIDTPDVNIEGPEG 4440

Query: 4441 KLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVESDLKGPEVDIEGPEG 4500
            KLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVESDLKGPEVDIEGPEG
Sbjct: 4441 KLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVESDLKGPEVDIEGPEG 4500

Query: 4501 KLKGPKFKMPDVHFKSPQISMSDIDLNLKGPKIKGDMDISVPKLEGDLKGPKVDVKGPKV 4560
            KLKGPKFKMPDVHFKSPQISMSDIDLNLKGPKIKGDMDISVPKLEGDLKGPKVDVKGPKV
Sbjct: 4501 KLKGPKFKMPDVHFKSPQISMSDIDLNLKGPKIKGDMDISVPKLEGDLKGPKVDVKGPKV 4560

Query: 4561 GIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKVKGDMDISLPKVEG 4620
            GIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKVKGDMDISLPKVEG
Sbjct: 4561 GIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKVKGDMDISLPKVEG 4620

Query: 4621 DLKGPEVDIRDPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKAD 4680
            DLKGPEVDIRDPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKAD
Sbjct: 4621 DLKGPEVDIRDPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKAD 4680

Query: 4681 IDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMSIKAPKISMPDIDLNLKGPKVKGDVD 4740
            IDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMSIKAPKISMPDIDLNLKGPKVKGDVD
Sbjct: 4681 IDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMSIKAPKISMPDIDLNLKGPKVKGDVD 4740

Query: 4741 VTLPKVEGDLKGPEADIKGPKVDINTPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDV 4800
            VTLPKVEGDLKGPEADIKGPKVDINTPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDV
Sbjct: 4741 VTLPKVEGDLKGPEADIKGPKVDINTPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDV 4800

Query: 4801 DVSLPKADIDVSGPKVDVDIPDVNIEGPDAKLKGPKFKMPEINIKAPKISIPDVDLDLKG 4860
            DVSLPKADIDVSGPKVDVDIPDVNIEGPDAKLKGPKFKMPEINIKAPKISIPDVDLDLKG
Sbjct: 4801 DVSLPKADIDVSGPKVDVDIPDVNIEGPDAKLKGPKFKMPEINIKAPKISIPDVDLDLKG 4860

Query: 4861 PKVKGDFDVSVPKVEGTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPD 4920
            PKVKGDFDVSVPKVEGTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPD
Sbjct: 4861 PKVKGDFDVSVPKVEGTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPD 4920

Query: 4921 VDLHLKAPKIGFSGPKLEGGEVDLKGPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKF 4980
            VDLHLKAPKIGFSGPKLEGGEVDLKGPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKF
Sbjct: 4921 VDLHLKAPKIGFSGPKLEGGEVDLKGPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKF 4980

Query: 4981 GFGAKSPKADIKSPSLDVTVPEAELNLETPEISVGGKGKKSKFKMPKIHMSGPKIKAKKQ 5040
            GFGAKSPKADIKSPSLDVTVPEAELNLETPEISVGGKGKKSKFKMPKIHMSGPKIKAKKQ
Sbjct: 4981 GFGAKSPKADIKSPSLDVTVPEAELNLETPEISVGGKGKKSKFKMPKIHMSGPKIKAKKQ 5040

Query: 5041 GFDLNVPGGEIDASLKAPDVDVNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEFDIKSP 5100
            GFDLNVPGGEIDASLKAPDVDVNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEFDIKSP
Sbjct: 5041 GFDLNVPGGEIDASLKAPDVDVNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEFDIKSP 5100

Query: 5101 KFKAEAPLPSPKLEGELQAPDLELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGDLK 5160
            KFKAEAPLPSPKLEGELQAPDLELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGDLK
Sbjct: 5101 KFKAEAPLPSPKLEGELQAPDLELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGDLK 5160

Query: 5161 GPKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPSVGLEGP 5220
            GPKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPSVGLEGP
Sbjct: 5161 GPKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPSVGLEGP 5220

Query: 5221 DVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSL 5280
            DVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSL
Sbjct: 5221 DVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSL 5280

Query: 5281 KGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLSGVGGKMQV 5340
            KGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLSGVGGKMQV
Sbjct: 5281 KGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLSGVGGKMQV 5340

Query: 5341 GGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGS 5400
            GGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGS
Sbjct: 5341 GGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGS 5400

Query: 5401 IKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPK 5460
            IKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPK
Sbjct: 5401 IKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPK 5460

Query: 5461 VKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISG 5520
            VKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISG
Sbjct: 5461 VKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISG 5520

Query: 5521 PEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPD 5580
            PEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPD
Sbjct: 5521 PEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPD 5580

Query: 5581 ISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQAPGL 5640
            ISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQAPGL
Sbjct: 5581 ISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQAPGL 5640

Query: 5641 SVSGPQGHLESGSGKVTFPKMKIPKFTFSGRELVGREMGVDVHFPKAEASIQAGAGDGEW 5700
            SVSGPQGHLESGSGKVTFPKMKIPKFTFSGRELVGREMGVDVHFPKAEASIQAGAGDGEW
Sbjct: 5641 SVSGPQGHLESGSGKVTFPKMKIPKFTFSGRELVGREMGVDVHFPKAEASIQAGAGDGEW 5700

Query: 5701 EESEVKLKKSKIKMPKFNFSKPKGKGGVTGSPEASISGSKGDLKSSKASLGSLEGEAEAE 5760
            EESEVKLKKSKIKMPKFNFSKPKGKGGVTGSPEASISGSKGDLKSSKASLGSLEGEAEAE
Sbjct: 5701 EESEVKLKKSKIKMPKFNFSKPKGKGGVTGSPEASISGSKGDLKSSKASLGSLEGEAEAE 5760

Query: 5761 ASSPKGKFSLFKSKKPRHRSNSFSDEREFSGPSTPTGTLEFEGGEVSLEGGKVKGKHGKL 5820
            ASSPKGKFSLFKSKKPRHRSNSFSDEREFSGPSTPTGTLEFEGGEVSLEGGKVKGKHGKL
Sbjct: 5761 ASSPKGKFSLFKSKKPRHRSNSFSDEREFSGPSTPTGTLEFEGGEVSLEGGKVKGKHGKL 5820

Query: 5821 KFGTFGGLGSKSKGHYEVTGSDDETGKLQGSGVSLASKKSRLSSSSSNDSGNKVGIQLPE 5880
            KFGTFGGLGSKSKGHYEVTGSDDETGKLQGSGVSLASKKSRLSSSSSNDSGNKVGIQLPE
Sbjct: 5821 KFGTFGGLGSKSKGHYEVTGSDDETGKLQGSGVSLASKKSRLSSSSSNDSGNKVGIQLPE 5880

Query: 5881 VELSVSTKKE 5890
            VELSVSTKKE
Sbjct: 5881 VELSVSTKKE 5890


>gi|156766050 AHNAK nucleoprotein 2 [Homo sapiens]
          Length = 5795

 Score = 1613 bits (4176), Expect = 0.0
 Identities = 1483/5261 (28%), Positives = 2327/5261 (44%), Gaps = 1312/5261 (24%)

Query: 1075 DLKGPKMKGNVDISAPKIEGEMQVPDVDIRGPKVD--------IKAPDVEGQGLDWSLKI 1126
            DLK PK   + +   P+ E  +  P    RG + D        +K  +VEG G  W   +
Sbjct: 488  DLKTPKFAFSTE-KEPERERRLSTPQ---RGKRQDASSKAGTGLKGEEVEGAG--W---M 538

Query: 1127 PKMKMPKFSMPSLKGEGPEVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKMP 1186
            P  +    +    +G+  + +  L +  +         E  D   E  EG+++ PKFK+P
Sbjct: 539  PGREPTTHA--EAQGDEGDGEEGLQRTRIT--------EEQDKGREDTEGQIRMPKFKIP 588

Query: 1187 EM------HFKTPKI-SMPDVDLHLKGP-----------------KVKGDVDVSVPKVEG 1222
             +      H KT +  +  D +   +G                  K K D D      + 
Sbjct: 589  SLGWSPSKHTKTGREKATEDTEQGREGEATATADRREQRRTEEGLKDKEDSDSMTNTTKI 648

Query: 1223 EMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMPKF--SMPGFKGEGREVDVNLPK 1280
            ++   +  +K  ++     + EV   D   KMPK KMP F  S PG K     VDV+ PK
Sbjct: 649  QLIHDEKRLKKEQI---LTEKEVATKDSKFKMPKFKMPLFGASAPG-KSMEASVDVSAPK 704

Query: 1281 ADIDVS--GPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLNLKGPKLK 1338
             + DVS    + D++  D+S++ P   L+    +  ++  K P+  +P+      G  LK
Sbjct: 705  VEADVSLLSMQGDLKTTDLSVQTPSADLE---VQDGQVDVKLPEGPLPE------GASLK 755

Query: 1339 GDVDVSLPEVEG-EMKVPDVDIKGPKVDISAPDVDVHGPDWHLKMPKVKMPKFSMPGFKG 1397
            G     LP+V+   +K+P VD+KGPK+D+  P  +V  PD       VKM   SM     
Sbjct: 756  GH----LPKVQRPSLKMPKVDLKGPKLDLKGPKAEVTAPD-------VKMSLSSM----- 799

Query: 1398 EGPEVDVKLPKADVDVSGPKMDAEVPDVNIEGPDAKLKGPKFKMPEMSIKPQKISIPDVG 1457
               EVDV+ P+A +D +  + D  + D  +   D+K K PKFKMP   +     S+ D  
Sbjct: 800  ---EVDVQAPRAKLDGARLEGDLSLADKEVTAKDSKFKMPKFKMPSFGVSAPGKSMED-S 855

Query: 1458 LHLKGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKVDINA------------PDVEVHGPD 1505
            + +  PK++ D  V++  ++G++KA D+ I+ P  D+              P  E  GP 
Sbjct: 856  VDVSAPKVEAD--VSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGPK 913

Query: 1506 WHLKMPKVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPD---------VNLE 1556
             HL  PKV+MP F MP    +GP++D+  PK DL   GPK ++  PD         V+++
Sbjct: 914  VHL--PKVEMPSFKMPKVDLKGPQIDVKGPKLDL--KGPKAEVTAPDGEVSLPSMEVDVQ 969

Query: 1557 APEGKLKGP------------------KFKMPSMNIQTHKISMPDVGL----NLKAPKLK 1594
            A + KL G                   KFKMP   + +  +S P   +    ++ APK+ 
Sbjct: 970  AQKAKLDGAWLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIKALVDVSAPKV- 1028

Query: 1595 TDVDVSLPKVEGDLKGPEIDVKAPKMDVNV--GDIDIEGPEG-------------KLKGP 1639
             + D+SLP ++GDLK  ++ ++    D+ V    +D++ PEG             K++ P
Sbjct: 1029 -EADLSLPSMQGDLKTTDLSIQPASTDLKVQADQVDVKLPEGHLPEGAGLKGHLPKVEMP 1087

Query: 1640 KFKMPEMHFKAPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKVDIDAP 1699
             FKMP++  K P++ +    L LK PK     +V+ P VE  +   +VD++ P   +D+ 
Sbjct: 1088 SFKMPKVALKGPQVDVKGPKLDLKSPKA----EVTAPDVEVSLPSVEVDVEAPGAKLDSA 1143

Query: 1700 DVE----VHDPDWHLKMPKMKMPKFSMPGFKAEGP------EVDVNLPKADIDVSGPSVD 1749
             +E    + D D   K  + KMPKF MP F A  P       VDV+ PK + DVS PS+ 
Sbjct: 1144 RLEGELSLADKDVTAKDSRFKMPKFKMPSFGASAPGKSIEASVDVSAPKVEADVSLPSMQ 1203

Query: 1750 TDAPDLDI---------------------EG--PEG--------KLKGSKFKMPKLNIKA 1778
             D    D+                     EG  PEG        K++    KMPK+++K 
Sbjct: 1204 GDLKTTDLSIQPPSADLEVHAGQVDVKLLEGHVPEGAGFKGHLPKVQMPSLKMPKVDLKG 1263

Query: 1779 PKVSMPDVDLNLKGPKLK---GEIDASVPELEGDLRGPQVDVKGPFVEAEVP--DVDLEC 1833
            P+V +    L+LKG K +    E+  S+P +E D++ P   + G  ++ ++   D D+  
Sbjct: 1264 PQVEVRGPKLDLKGHKAEVTAHEVAVSLPSVEVDMQAPGAKLDGAQLDGDLSLADKDVTA 1323

Query: 1834 PDAKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDADVSVPKLEGDLTGPSVGVEV 1893
             D+K K PKFKMP     AP  S+ +  + L  PKV  +AD+S+P ++GDL    + ++ 
Sbjct: 1324 KDSKFKMPKFKMPSFGVSAPGKSI-EASVDLSAPKV--EADMSLPSMQGDLKTTDLSIQP 1380

Query: 1894 PDVELEC--------------PDA--------KLKGPKFKMPDMHFKAPKISMPDVDLHL 1931
            P  +LE               P+         KL+ P FK+P +  K P+I +    L L
Sbjct: 1381 PSTDLELQAGQLDVKLPEGPVPEGAGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKLDL 1440

Query: 1932 KGPKVK---GDVDVSVPKLEGDLTGPSVGVE---------VPDVELECPDAKLKGPKFKM 1979
            K PKV+    DV+VS+P +E D+  P   ++         + D +L   D+K K PKFKM
Sbjct: 1441 KDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGGRLEEDMSLADKDLTTKDSKFKMPKFKM 1500

Query: 1980 PEMHFKTPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKMDID--APDV 2037
            P      P  S+ +  + +  PKV+ D  VS+P ++G++K  D+ I+ P  D++  A  V
Sbjct: 1501 PSFGVSAPGKSI-EASVDVSAPKVEAD--VSLPSMQGDLKATDLSIQPPSADLEVQAGQV 1557

Query: 2038 DVHGPDWHLK--------MPKMKMPKFSMPGFKAEGPEVDVNLPKADVVVSGPKVDVEVP 2089
            DV  P+  +         +PK++MP F MP    +GP++DV  PK D+   GPKV+V  P
Sbjct: 1558 DVKLPEGPVSEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDL--KGPKVEVTAP 1615

Query: 2090 DVSL---------EGPEGKLKGPKLK-----------MPEMHFKAPKISMPDVDLHLKGP 2129
            DV +         + P  KL G +L+             +  FK PK  MP   +   G 
Sbjct: 1616 DVKMSLSSMEVDVQAPRAKLDGAQLEGDLSLADKAVTAKDSKFKMPKFKMPSFGVSAPGK 1675

Query: 2130 KVKGDVDVSLPKLEGDLTGPSV--DVEVPDVELECPDA---------------------- 2165
             ++  VDVS PK+E D++ PS+  D++  D+ ++ P A                      
Sbjct: 1676 SIEASVDVSEPKVEADVSLPSMQGDLKTTDLSIQSPSADLEVQAGQVNVKLPEGPLPEGA 1735

Query: 2166 -------KLKGPKFKMPEMHFKTPKISMPDVNLNLKGPKVK---GDMDVSVPKVEGEMKV 2215
                   K++ P  KMP++  K P++ +    L+LKGPK +    D++VS+P VE +++ 
Sbjct: 1736 GFKGHLPKVQMPSLKMPKVALKGPQMDVKGPKLDLKGPKAEVMAPDVEVSLPSVEVDVEA 1795

Query: 2216 PDVDIRGPKV--DIDAPDVDVHGPDWHLKMPKMKMPKF--SMPGFKGEGPEVDVNLPKAD 2271
            P   +   ++  D+   D DV   D   KMPK KMP F  S PG K     VDV+ PK +
Sbjct: 1796 PGAKLDSVRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPG-KSIEASVDVSAPKVE 1854

Query: 2272 VDVSGPKVD------------------VEVPDVSLEGPEGK------LKG-------PKF 2300
             +VS P +                   V+   V ++ PEG+      LKG       P F
Sbjct: 1855 AEVSLPSMQGDLKTTDLCIPLPSADLVVQAGQVDMKLPEGQVPEGAGLKGHLPKVDMPSF 1914

Query: 2301 KMPEMHFKTPKISMPDVDFNLKGPKIK---GDVDVSAPKLEGELKGPELDVKGPKLDADM 2357
            KMP++  K P+  +     +LKGPK +    DV+VS P +E +++  +  + G +L+ D+
Sbjct: 1915 KMPKVDLKGPQTDVKGAKLDLKGPKAEVTAPDVEVSLPSMEVDVQAQKAKLDGARLEGDL 1974

Query: 2358 P--EVAVEGPNGKWKTPKFKMPDMHFKAP-----------------KISMPDL------- 2391
               +  +   + K+K PKFKMP     AP                  +S+P +       
Sbjct: 1975 SLADKDMTAKDSKFKMPKFKMPSFGVSAPGRSIEASVDVPAPKVEADVSLPSMQGDLKTT 2034

Query: 2392 DLHLKSPKAK-----GEVDVDVPK--------LEG--------DLKGPHVDVSGPDIDIE 2430
            DL ++ P A      G+VDV +P+        L+G         LK P VD+ GP +DI+
Sbjct: 2035 DLSIQPPSADLKVQTGQVDVKLPEGHVPEGAGLKGHLPKVEMPSLKMPKVDLKGPQVDIK 2094

Query: 2431 GPEGKLKGPKFKM-----------------------------------------PDMHFK 2449
            GP+  LK PK +M                                          D  FK
Sbjct: 2095 GPKLDLKDPKVEMRVPDVEVSLPSMEVDVQAPRAKLDSAHLQGDLTLANKDLTTKDSKFK 2154

Query: 2450 APNISMPDVDLNLKGPKIKGDVDVSVPEVEGKLEVP------------------DMNIRG 2491
             P   MP   ++  G  I+  VDVS P+VE  + +P                  D+ ++ 
Sbjct: 2155 MPKFKMPSFGVSAPGKSIEASVDVSPPKVEADMSLPSMQGDLKTTDLSIQPLSADVKVQA 2214

Query: 2492 PKVDVNAPDVQAPDW-HLK--MPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDI 2548
             +VDV   +   P+   LK  +PK++MP F +P    +GPE+D+  PK  +D+  PKV++
Sbjct: 2215 GQVDVKLLEGPVPEEVGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPK--LDLKDPKVEV 2272

Query: 2549 EGPDV---------NIEGPEGKLKGPKLK-----------MPEMNIKAPKISMPDFDLHL 2588
              PDV         +++ P  KL G +L+             +   K PK  M  F +  
Sbjct: 2273 TAPDVEVSLPSVEVDVKAPGAKLDGARLEGDMSLADKDVTAKDSKFKMPKFKMLSFGVSA 2332

Query: 2589 KGPKV---------KGDVDVSLPKVEGDLKGPEVDIKGPKVD--INAPDVGVQGPDWHLK 2637
             G  +         K + DVSLP ++GDLK  ++ ++ P  D  + A  V V+ P+  + 
Sbjct: 2333 LGKSIEASADVSALKVEADVSLPSMQGDLKTTDLSVQPPSADLEVQAGQVDVKLPEGPVP 2392

Query: 2638 --------MPKVKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPKVDIEGPDV-------- 2681
                    +PK++MP F MP    +GP  DVK PK  +D+ GPK D+  PDV        
Sbjct: 2393 EGAGLKGHLPKLQMPSFKMPKVDLKGPQIDVKGPK--LDLKGPKTDVMAPDVEVSQPSVE 2450

Query: 2682 -NIEGPEGKLKGPKFK-----------MPEMNIKAPKISMPDIDLNLKGPKVKGDVDVSL 2729
             ++E P  KL G   +             +   K PK  MP   ++  G  ++  VDVS 
Sbjct: 2451 VDVEAPGAKLDGAWLEGDLSVADKDVTTKDSRFKIPKFKMPSFGVSAPGKSIEASVDVSA 2510

Query: 2730 PKVE---------GDLKGPEVDIKGPKVDID--APDVDVHGPDWHLK--------MPKIK 2770
            PKVE         GDLK  ++ I+ P  D++  A  VDV  P+  +         +PK++
Sbjct: 2511 PKVEADGSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGLKGHLPKVQ 2570

Query: 2771 MPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDV---------NIEGPEGKW--- 2818
            MP   MP    +GP +DV  PK  +D+ GPK +V  PDV         +++ P  K    
Sbjct: 2571 MPSFKMPEMDLKGPQLDVKGPK--LDLKGPKAEVTAPDVEMSLSSMEVDVQAPRAKLDGA 2628

Query: 2819 ---------------KSPKFKMPEMHFKTPKISMP--DIDLNLTGPKIKGDVDVTGPKVE 2861
                           K  KFKMP+    + ++S P   I+  +   ++K + D++ P ++
Sbjct: 2629 RLEGDLSLADKGVTAKDSKFKMPKFKMPSFRVSAPGESIEALVDVSELKVEADMSLPSMQ 2688

Query: 2862 GDLKGPEVDLKGPKVDIDVP--DVNVQGPDWHLK--------MPKMKMPKFSMPGFKAEG 2911
            GDLK  ++ ++ P   ++V    V+V+ P+ H+         +PK++MP F MP    +G
Sbjct: 2689 GDLKTTDISIQPPSAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKLQMPSFKMPEVDLKG 2748

Query: 2912 PEVDVNLPKADVDVSGPKVDVEGPDV---------NIEGPEGKLKGPKFK---------- 2952
            P++DV  P  +VD+ GPK +V  PDV         +++ P  KL G + +          
Sbjct: 2749 PQIDVKGP--NVDLKGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGM 2806

Query: 2953 -MPEMNIKAPKIPMPDFDLHLKGPKVKGDVDIS---------LPKVEGDLKGPEVDIRGP 3002
               +   K PK  MP F +   G  ++  VD+S          P ++GDLK  ++ I+ P
Sbjct: 2807 TAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSELKVEADGSFPSMQGDLKTTDIRIQPP 2866

Query: 3003 --QVDIDVPDVGVQGPDWHLK--------MPKVKMPKFSMPGFKGEGPDVDVNLPKADLD 3052
              Q+++    V V+ P+ H+         +PKV+MP F MP    +GP +DV  PK  LD
Sbjct: 2867 SAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPK--LD 2924

Query: 3053 VSGPKVDIDVPDV---------NIEGPEGKLKG-----------------------PKFK 3080
            + GPK ++  PDV         ++E P  KL G                       PKFK
Sbjct: 2925 LKGPKAEVTAPDVEVSLPSVEVDVEAPRAKLDGARLEGDLSLADKDVTAKDSKFKMPKFK 2984

Query: 3081 MPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMKVPDVDIKGP--KVDINAPD 3138
            MP   + AP  S+ ++ +++  PKV+ +  VSLP ++GD+K  D+ I+ P  ++++ A  
Sbjct: 2985 MPSFGVSAPGKSI-EVSVDVSAPKVEAE--VSLPSMQGDLKTTDISIEPPSAQLEVQAGQ 3041

Query: 3139 VDVQGPDWHLK--------MPKIKMPKISMPGFKGEGPEVDVNLPKADLDVSGPKVDVDV 3190
            VD++ P+ H+         +PK++MP   MP    +GP++DV  PK  LD+ GPK DV  
Sbjct: 3042 VDLKLPEGHVPEGAGLKGHLPKLQMPSFKMPKVDRKGPQIDVKGPK--LDLKGPKTDVTA 3099

Query: 3191 PDVNIEGP--------------------------------DAKLKGPKFKMPEMNIKAPK 3218
            PDV +  P                                D+K K PKFKMP   + AP 
Sbjct: 3100 PDVEVSQPGMEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPG 3159

Query: 3219 ISMPDLDLNLKGPKMKGEVDVSLANVEGDLKGPALDIKGP--KIDVDAPDIDIHGPD--- 3273
             S+  L +++  PK+  E D+SL +++GDLK   + I+ P  +++V A  +D+  P+   
Sbjct: 3160 KSIEVL-VDVSAPKV--EADLSLPSMQGDLKNTDISIEPPSAQLEVQAGQVDVKLPEGHV 3216

Query: 3274 ---AKLKG--PKLKMPDMHVNMPKISMPEIDLNLKGSKLKGDVDVSGPKLEGDIKAPSLD 3328
               A LKG  PKL+MP     MPK+      +++KG KL    D+ GPK+  D+ AP ++
Sbjct: 3217 LEGAGLKGHLPKLQMPSF--KMPKVDRKGPQIDIKGPKL----DLKGPKM--DVTAPDVE 3268

Query: 3329 IKGP--EVDVSGPKLNIEGK--------------SKKSRFKLPKFNFSGSKVQTP----- 3367
            +  P  EVDV  P   ++G               +K S+FK+PKF     +   P     
Sbjct: 3269 VSQPSMEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSYRASAPGKSIQ 3328

Query: 3368 -EVDVKGKKPDIDITGPK-----------VDINAPDVEVQG------------------- 3396
              VDV   K + D++ P            + + + D+EVQ                    
Sbjct: 3329 ASVDVSAPKAEADVSLPSMQGDLKTTDLSIQLPSVDLEVQAGQVDVKLPEGHVPEGAGLK 3388

Query: 3397 ----KVKGSKFKMPFLSISSPKVSMPDVELNLKSPKVK---GDLDIAGPNLEGDFKGP-- 3447
                KV+   FKMP + + SP+V +   +L+LK PK +    D++++ P++E D + P  
Sbjct: 3389 GHLPKVEMPSFKMPKVDLKSPQVDIKGPKLDLKVPKAEVTVPDVEVSLPSVEVDVQAPRA 3448

Query: 3448 KVDIKAPEVNLNAPDVDVHGPDWNLKMPKMKMPKFSVSG--------LKAEGPDVAVD-- 3497
            K+D    E +L+  + DV   D   KMPK KMP F VS         L    P V  D  
Sbjct: 3449 KLDGARLEGDLSLAEKDVTAKDSKFKMPKFKMPSFGVSAPGRSIEASLDVSAPKVEADVS 3508

Query: 3498 -------LPKGDINIEGPSMNIEGPDLNV-----EGP--EG-GLKG-------PKFKMPD 3535
                   L   D++I+ PS ++E   + V     EGP  EG GLKG       P  K P 
Sbjct: 3509 LSSMQGDLKATDLSIQPPSADLEVQAVQVDVELLEGPVPEGAGLKGHLPKVEMPSLKTPK 3568

Query: 3536 MNIKAPKISMPDIDLNLKGPKVK---GDVDISLPKLEGDLKGPEVDIKGPKV--DINAPD 3590
            +++K P+I +    L+LKGPK +    DV++SLP +E D++ P+  +   ++  D++  D
Sbjct: 3569 VDLKGPQIDVKGPKLDLKGPKAEVRVPDVEVSLPSVEVDVQAPKAKLDAGRLEGDLSLAD 3628

Query: 3591 VDVHGPDWHLKMPKVKMPKF--SMPGFKGEGPEVDVTLPKADIDISGPNV--DVDVPDVN 3646
             DV   D   KMPK KMP F  S PG K     VDV+ PK + D+S P++  D+   D++
Sbjct: 3629 KDVTAKDSKFKMPKFKMPSFRVSAPG-KSMEASVDVSAPKVEADVSLPSMQGDLKTTDLS 3687

Query: 3647 IEGPDAKLKG------------------------PKFKMPEMNIKAPKISMPDFDLNLKG 3682
            I+ P A LK                         PK +MP  ++K PK+ +    +++KG
Sbjct: 3688 IQPPSADLKVQAGQMDVKLPEGQVPEGAGLKEHLPKVEMP--SLKMPKVDLKGPQVDIKG 3745

Query: 3683 PKMK----------GDVVVSLPKVEGDLKGPEVDIKGPKV--DIDTPDINIEGSEGKFKG 3730
            PK+            DV VSLP VE D++ P   +   ++  D+   D ++   + KFK 
Sbjct: 3746 PKLDLKVSKAEVTAPDVEVSLPSVEVDVQAPRAKLDSAQLEGDLSLADKDVTAKDSKFKM 3805

Query: 3731 PKFKIPEMHLKAP--------KISMPDIDLNLKGPKVKGDVDVS---------------- 3766
            PKFK+P   + AP         +S P ++ ++  P ++GD+  +                
Sbjct: 3806 PKFKMPSFGVSAPGKSIEASVHVSAPKVEADVSLPSMQGDLKTTDLSIQPHSADLTVQAR 3865

Query: 3767 --------------------LPKMEG--------DLKGPEVDIKGPKVDINAPDVDVQGP 3798
                                LPK++         DLKGPE+DIKGPK+D+  P V+V  P
Sbjct: 3866 QVDMKLLEGHVPEEAGLKGHLPKVQMPSFKMPKVDLKGPEIDIKGPKLDLKDPKVEVTAP 3925

Query: 3799 DWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPEGKLKG 3858
            D  + +P V               +VDV  P A LD +  + D+ + D ++   + K K 
Sbjct: 3926 DVEVSLPSV---------------EVDVEAPGAKLDGARLEGDLSLADKDMTAKDSKFKM 3970

Query: 3859 PKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMQVPDLDIKGPKVD--I 3916
            PKFKMP   + AP  SM +  +++  PKV  + DVSLP ++GD++  DL ++ P  D  +
Sbjct: 3971 PKFKMPSFGVSAPGKSM-EASVDVTAPKV--EADVSLPSMQGDLKATDLSVQPPSADLEV 4027

Query: 3917 NAPDVDVRGPDWHL--------KMPKIKMPKISMPGFKGEGPEVDVNLPKADLDVSGPKV 3968
             A  VDV+ P+  +         +PK++MP   MP    +GP++DV  PK  LD+ GPK 
Sbjct: 4028 QAGQVDVKLPEGPVPEGASLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPK--LDLKGPKA 4085

Query: 3969 DVDVPD---------VNIEGPDAKLKG-----------------------PKFKMPEMNI 3996
            +V  PD         V+++ P AKL G                       PKFKMP   +
Sbjct: 4086 EVTAPDVKMSLSSMEVDVQAPRAKLDGVQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGV 4145

Query: 3997 KAPKISMPDFDLHLKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKVDID--APDVDVHGP 4054
             AP  SM   +  +   ++K   DVSLP M+GDLK  ++ I+ P  D++  A  VDV  P
Sbjct: 4146 SAPGKSM---EASVDVSELKAKADVSLPSMQGDLKTTDLSIQSPSADLEVQAGQVDVKLP 4202

Query: 4055 DWHL--------KMPKVKMPKFSMPGFKGEGPEVDVNLPKADIDVSGPKVDIDTP----- 4101
            +  L         +PKV+MP   MP    +GP+VDV  PK  +D+ GPK D+ TP     
Sbjct: 4203 EGPLPKGAGLKGHLPKVQMPCLKMPKVALKGPQVDVKGPK--LDLKGPKADVMTPVVEVS 4260

Query: 4102 ----DIDIHGP-----------------------EGKLKGPKFKMPDLHLKAPKISMPEV 4134
                ++D+  P                       + K K PKFKMP   + AP  S   +
Sbjct: 4261 LPSMEVDVEAPGAKLDSVRLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGKS---I 4317

Query: 4135 DLNLKGPKMKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDVP--DVDVQGPDWHL------ 4186
            + +L    +K + DVSLP ++GDLK   + I+ P  D++V     DV+ P+  +      
Sbjct: 4318 EASLDVSALKVEADVSLPSMQGDLKTTHLSIQPPSADLEVQAGQEDVKLPEGPVHEGAGL 4377

Query: 4187 --KMPKVKMPKFSMPGFKGEGPDVDVNLPKADL-----DVSGPKVDIDVP--DVNIEGPD 4237
               +PK++MP F +P    +GP +DVN+PK DL     +V+ P +D+ +P  +V+I+ P 
Sbjct: 4378 KGHLPKLQMPSFKVPKVDLKGPQIDVNVPKLDLKGPKVEVTSPNLDVSLPSMEVDIQAPG 4437

Query: 4238 AKLKGPKFK-----------MPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDL 4286
            AKL   + +             +   K PK  MP F +   G  ++  VDVS PK+E D+
Sbjct: 4438 AKLDSTRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGMLSPGKSIEVSVDVSAPKMEADM 4497

Query: 4287 KGPEV--DIKGPKVDIDAP--DVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVTLPK 4342
              P +  D+K   + I AP  D++V      LK+P+  MP+  + G KG  P V++   K
Sbjct: 4498 SIPSMQGDLKTTDLRIQAPSADLEVQAGQVDLKLPEGHMPE--VAGLKGHLPKVEMPSFK 4555

Query: 4343 ADIEISGPKVDIDAPDVSIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDFNLKGPKVKGD 4402
                   PKVD+  P V ++GP   LKGPK       + AP                  D
Sbjct: 4556 M------PKVDLKGPQVDVKGPKLDLKGPK-----AEVMAP------------------D 4586

Query: 4403 VDVSLPKVEGDLKGPEIDIKGPSL--DIDTPDVNIEGPEGKLKGPKFKMPEMNIKAPKIS 4460
            V+VSLP VE D++ P   + G  L  D+     ++ G + K +GPK         + K+S
Sbjct: 4587 VEVSLPSVETDVQAPGSMLDGARLEGDLSLAHEDVAGKDSKFQGPKLSTSGFEWSSKKVS 4646

Query: 4461 MPDFDLHLKGPKVKGDVDVSLPKVESDLKGPEVDIEGPEGKL------KGPKFKMPDVHF 4514
            M   +  ++G     +   + P VES +   ++     +G L       G   K   +HF
Sbjct: 4647 MSSSE--IEGNVTFHEKTSTFPIVESVVHEGDLHDPSRDGNLGLAVGEVGMDSKFKKLHF 4704

Query: 4515 KSPQISMSDIDLNLKGPKIKGDMDISVPKLEGDLKGPKVDVKGPKVGIDTPDIDIHGPEG 4574
            K P++S S    + K PK     D  VP              G K  I    I +   E 
Sbjct: 4705 KVPKVSFS----STKTPK-----DSLVP--------------GAKSSIGLSTIPLSSSEC 4741

Query: 4575 KLKGPKFKMPDLH-LKAPKISMPEVDLNLKGPKVKGDMDISLPKVEGDLKGPEVDIRDPK 4633
                  F++  +     P + MP+V            +D++ P  E  +  P  D+   K
Sbjct: 4742 S----SFELQQVSACSEPSMQMPKVGF---AGFPSSRLDLTGPHFESSILSPCEDVTLTK 4794

Query: 4634 VDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKAD--IDVSGPKVDVD 4691
              + VP   +  P+  L++P               G   D+ LPK +   D+  P+    
Sbjct: 4795 YQVTVPRAAL-APELALEIP--------------SGSQADIPLPKTECSTDLQPPE---G 4836

Query: 4692 VPDVNIEGPDAKLKG-----------PKFKMPEMSIKAPKISMPDIDLN------LKGPK 4734
            VP    E     L             PKF  P+     P++++P+ DL+      +  P 
Sbjct: 4837 VPTSQAESHSGPLNSMIPVSLGQVSFPKFYKPKFVFSVPQMAVPEGDLHAAVGAPVMSPL 4896

Query: 4735 VKGD-VDVTLPKVEGD------LKGPEADIKGPKVDINTP------DVDVHGPDWHLKMP 4781
              G+ V   LP  +         +GPE  +   +  +  P      D D  G    LKMP
Sbjct: 4897 SPGERVQCPLPSTQLPSPGTCVSQGPEELVASLQTSVVAPGEAPSEDADHEGKGSPLKMP 4956

Query: 4782 KVKMPKFSMPGFKGEGPDVDVSLPKADIDVS--------GPK--VDVDIPDVNIEGPDAK 4831
            K+K+P F     K  GP VD      D  +S         P+  + +D+P    +G   +
Sbjct: 4957 KIKLPSFRWSPKKETGPKVDPECSVEDSKLSLVLDKDEVAPQSAIHMDLPPER-DGEKGR 5015

Query: 4832 LKGPKFKMPEI---NIKAPK--ISIP--DVDLDLKGPKVKGDF-DVSVPKVEGTLKGPEV 4883
               P F MP++    +KA K  +S+P  DVD  L      G F D      +G   G   
Sbjct: 5016 STKPGFAMPKLALPKMKASKSGVSLPQRDVDPSLSSATAGGSFQDTEKASSDGGRGG--- 5072

Query: 4884 DLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLHLKAPKIGFSGPKLEGGEVD 4943
               G      G +    G +L  P + I                P +GF+ P L   +  
Sbjct: 5073 --LGATASATGSE----GVNLHRPQVHI----------------PSLGFAKPDLRSSKAK 5110

Query: 4944 LKGPKVEAPSLDVHMDSPDINIEGP-------DVKIPKFKKPKFGFGAKSPKADIKSPSL 4996
            +   +V  P  D+ +   D++ EG        DV + +      G G      D   PS 
Sbjct: 5111 V---EVSQPEADLPLPKHDLSTEGDSRGCGLGDVPVSQ----PCGEGIAPTPEDPLQPS- 5162

Query: 4997 DVTVPEAE-LNLETPEISVGGK-GKKSKFKMPKIHMSGPKIKAKKQGFDLNVPGGEID-A 5053
                P+AE L +E+PE     K  ++S FKMPK  M   +   + +G       G+++ A
Sbjct: 5163 -CRKPDAEVLTVESPEEEAMTKYSQESWFKMPKFRMPSLRRSFRDRG-----GAGKLEVA 5216

Query: 5054 SLKAPDVDVNIAGPDAALKVD---VKSPKTKKTMFGKMYFPDVEFDIKSPKFKAEAPLPS 5110
              +AP       G +AA KV    V     +  M   +  P+ + ++ + + K+   +  
Sbjct: 5217 QTQAPAA----TGGEAAAKVKEFLVSGSNVEAAM--SLQLPEADAEVTASESKSSTDI-- 5268

Query: 5111 PKLEGELQAPDLELSLPAIHVEGLDIKAKAPKV---------KMPDVDISVPKIEGDLKG 5161
              L  +L +  L+L L    + G ++     ++         +MP + +   ++   L G
Sbjct: 5269 --LRCDLDSTGLKLHLSTAGMTGDELSTSEVRIHPSKGPLPFQMPGMRLPETQV---LPG 5323

Query: 5162 PKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPS-VGLEGP 5220
               +  L  P  ++  ++ K +  S        S P+  + LK      D+PS + +   
Sbjct: 5324 EIDETPLSKPGHDLASMEDKTEKWS--------SQPEGPLKLKASST--DMPSQISVVNV 5373

Query: 5221 DVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVK-LEGPDVS 5279
            D   +     +KFPK  +P+   P               PS E D+  P V+ ++ P+ +
Sbjct: 5374 DQLWEDSVLTVKFPKLMVPRFSFPA--------------PSSEDDVFIPTVREVQCPEAN 5419

Query: 5280 L------KGPGV---DLPSVNLSMPKVSGPDLDLNLKGPSL 5311
            +      + PG+    +      +P     DL+L L+ P +
Sbjct: 5420 IDTALCKESPGLWGASILKAGAGVPGEQPVDLNLPLEAPPI 5460



 Score = 1605 bits (4155), Expect = 0.0
 Identities = 1415/5031 (28%), Positives = 2248/5031 (44%), Gaps = 1216/5031 (24%)

Query: 798  EGKLKGPKFKMPEMNIKVPKISMPDVDLHLKGPNVKGEYDVTMPKVESEIKVPDVELKSA 857
            + K K PKFKMP      P  SM +  + +  P V  E DV++  ++ ++K  D+ +++ 
Sbjct: 672  DSKFKMPKFKMPLFGASAPGKSM-EASVDVSAPKV--EADVSLLSMQGDLKTTDLSVQTP 728

Query: 858  KMDIDVPD--VEVQGPDWHLK--------MPKMKMPKFSMPGFKAEGPEVDVNLPKADVD 907
              D++V D  V+V+ P+  L         +PK++ P   MP    +GP++D+  PKA+V 
Sbjct: 729  SADLEVQDGQVDVKLPEGPLPEGASLKGHLPKVQRPSLKMPKVDLKGPKLDLKGPKAEVT 788

Query: 908  ISGPKVGVEVPDVNIEGPEGKLKG-----------------------PKFKMPEMNIKAP 944
                K+ +   +V+++ P  KL G                       PKFKMP   + AP
Sbjct: 789  APDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKEVTAKDSKFKMPKFKMPSFGVSAP 848

Query: 945  KISMPDVDLHMKGPKVKGEYDMTVPKLEGDLKGPKVDVSAP--DVEMQGPDWNLK----- 997
              SM D  + +  PKV  E D+++  ++GDLK   + +  P  D+E+Q    ++K     
Sbjct: 849  GKSMED-SVDVSAPKV--EADVSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGP 905

Query: 998  ----------MPKIKMPKFSMPSLKGEGPEFDVNLSKANVDISAPKVDTNAPD--LSLEG 1045
                      +PK++MP F MP +  +GP+ DV   K  +D+  PK +  APD  +SL  
Sbjct: 906  VPEGAGPKVHLPKVEMPSFKMPKVDLKGPQIDVKGPK--LDLKGPKAEVTAPDGEVSLPS 963

Query: 1046 PEGKLKGPKFKM------------------PEMHFRAPKMSLPDVDLDLKGPKMKGNVDI 1087
             E  ++  K K+                   +  F+ PK  +P   +   G  +K  VD+
Sbjct: 964  MEVDVQAQKAKLDGAWLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIKALVDV 1023

Query: 1088 SAPKIEGEMQVP------------------DVDIRGPKVDIKAPD---VEGQGLDWSLKI 1126
            SAPK+E ++ +P                  D+ ++  +VD+K P+    EG GL   L  
Sbjct: 1024 SAPKVEADLSLPSMQGDLKTTDLSIQPASTDLKVQADQVDVKLPEGHLPEGAGLKGHL-- 1081

Query: 1127 PKMKMPKFSMPSLKGEGPEVDVNLPKADVVVSGPKVDIEAPD---------VSLEGPEGK 1177
            PK++MP F MP +  +GP+VDV  PK D  +  PK ++ APD         V +E P  K
Sbjct: 1082 PKVEMPSFKMPKVALKGPQVDVKGPKLD--LKSPKAEVTAPDVEVSLPSVEVDVEAPGAK 1139

Query: 1178 LKGPKFK-----------MPEMHFKTPKISMPDVDLHLKGPKVKGDVDVSVPKVE----- 1221
            L   + +             +  FK PK  MP       G  ++  VDVS PKVE     
Sbjct: 1140 LDSARLEGELSLADKDVTAKDSRFKMPKFKMPSFGASAPGKSIEASVDVSAPKVEADVSL 1199

Query: 1222 ----GEMKVPDVEIKGPKMDID--APDVEVQGPDWH------------------LKMPKM 1257
                G++K  D+ I+ P  D++  A  V+V+  + H                  LKMPK+
Sbjct: 1200 PSMQGDLKTTDLSIQPPSADLEVHAGQVDVKLLEGHVPEGAGFKGHLPKVQMPSLKMPKV 1259

Query: 1258 KM---------PKFSMPGFKGE--GREVDVNLPKADIDVSGPKV---------DVEVPDV 1297
             +         PK  + G K E    EV V+LP  ++D+  P           D+ + D 
Sbjct: 1260 DLKGPQVEVRGPKLDLKGHKAEVTAHEVAVSLPSVEVDMQAPGAKLDGAQLDGDLSLADK 1319

Query: 1298 SLEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLNLKGPKLKGDVDVSLPEVEGEMKVPDV 1357
             +   + K K PKFKMP     AP  S+ +  ++L  PK+  + D+SLP ++G++K  D+
Sbjct: 1320 DVTAKDSKFKMPKFKMPSFGVSAPGKSI-EASVDLSAPKV--EADMSLPSMQGDLKTTDL 1376

Query: 1358 DIKGPKVD--ISAPDVDVHGPDWHL--------KMPKVKMPKFSMPGFKGEGPEVDVKLP 1407
             I+ P  D  + A  +DV  P+  +         +PK++MP F +P    +GPE+D+K P
Sbjct: 1377 SIQPPSTDLELQAGQLDVKLPEGPVPEGAGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGP 1436

Query: 1408 KAD-----VDVSGPKMDAEVP--DVNIEGPDAKLKG-----------------------P 1437
            K D     V+V+ P ++  +P  +V++E P AKL G                       P
Sbjct: 1437 KLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGGRLEEDMSLADKDLTTKDSKFKMP 1496

Query: 1438 KFKMPEMSIKPQKISIPDVGLHLKGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKVD--IN 1495
            KFKMP   +     SI +  + +  PK++   DV++P ++G++KA D+ I+ P  D  + 
Sbjct: 1497 KFKMPSFGVSAPGKSI-EASVDVSAPKVEA--DVSLPSMQGDLKATDLSIQPPSADLEVQ 1553

Query: 1496 APDVEVHGPDWHLK--------MPKVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKVD 1547
            A  V+V  P+  +         +PKV+MP F MP    +GP++D+  PK DL   GPKV+
Sbjct: 1554 AGQVDVKLPEGPVSEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDL--KGPKVE 1611

Query: 1548 IDVPD---------VNLEAPEGKLKG------------------PKFKMPSMNIQTHKIS 1580
            +  PD         V+++AP  KL G                   KFKMP   + +  +S
Sbjct: 1612 VTAPDVKMSLSSMEVDVQAPRAKLDGAQLEGDLSLADKAVTAKDSKFKMPKFKMPSFGVS 1671

Query: 1581 MP--DVGLNLKAPKLKTDVDVSLPKVEGDLKGPEIDVKAPKMDVNV--GDIDIEGPEG-- 1634
             P   +  ++   + K + DVSLP ++GDLK  ++ +++P  D+ V  G ++++ PEG  
Sbjct: 1672 APGKSIEASVDVSEPKVEADVSLPSMQGDLKTTDLSIQSPSADLEVQAGQVNVKLPEGPL 1731

Query: 1635 -----------KLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVK---GDMDVSVPKVEG 1680
                       K++ P  KMP++  K P++ +    L LKGPK +    D++VS+P VE 
Sbjct: 1732 PEGAGFKGHLPKVQMPSLKMPKVALKGPQMDVKGPKLDLKGPKAEVMAPDVEVSLPSVEV 1791

Query: 1681 EMKVPDVDIKGPKV--DIDAPDVEVHDPDWHLKMPKMKMPKF--SMPGFKAEGPEVDVNL 1736
            +++ P   +   ++  D+   D +V   D   KMPK KMP F  S PG   E   VDV+ 
Sbjct: 1792 DVEAPGAKLDSVRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEA-SVDVSA 1850

Query: 1737 PKADIDVSGPSVDTD------------------APDLDIEGPEGK------LKG------ 1766
            PK + +VS PS+  D                  A  +D++ PEG+      LKG      
Sbjct: 1851 PKVEAEVSLPSMQGDLKTTDLCIPLPSADLVVQAGQVDMKLPEGQVPEGAGLKGHLPKVD 1910

Query: 1767 -SKFKMPKLNIKAPKVSMPDVDLNLKGPKLK---GEIDASVPELEGDLRGPQVDVKGPFV 1822
               FKMPK+++K P+  +    L+LKGPK +    +++ S+P +E D++  +  + G  +
Sbjct: 1911 MPSFKMPKVDLKGPQTDVKGAKLDLKGPKAEVTAPDVEVSLPSMEVDVQAQKAKLDGARL 1970

Query: 1823 EAE--VPDVDLECPDAKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDADVSVPKL 1880
            E +  + D D+   D+K K PKFKMP     AP  S+ +  + +  PKV  +ADVS+P +
Sbjct: 1971 EGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGRSI-EASVDVPAPKV--EADVSLPSM 2027

Query: 1881 EGDLTGPSVGVEVP---------DVELECPD------AKLKG-------PKFKMPDMHFK 1918
            +GDL    + ++ P          V+++ P+      A LKG       P  KMP +  K
Sbjct: 2028 QGDLKTTDLSIQPPSADLKVQTGQVDVKLPEGHVPEGAGLKGHLPKVEMPSLKMPKVDLK 2087

Query: 1919 APKISMPDVDLHLKGPKVK---GDVDVSVPKLEGDLTGPSVGVE---------VPDVELE 1966
             P++ +    L LK PKV+    DV+VS+P +E D+  P   ++         + + +L 
Sbjct: 2088 GPQVDIKGPKLDLKDPKVEMRVPDVEVSLPSMEVDVQAPRAKLDSAHLQGDLTLANKDLT 2147

Query: 1967 CPDAKLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIK 2026
              D+K K PKFKMP      P  S+ +  + +  PKV+ DM  S+P ++G++K  D+ I+
Sbjct: 2148 TKDSKFKMPKFKMPSFGVSAPGKSI-EASVDVSPPKVEADM--SLPSMQGDLKTTDLSIQ 2204

Query: 2027 GPKMD--IDAPDVDV---HGP---DWHLK--MPKMKMPKFSMPGFKAEGPEVDVNLPKAD 2076
                D  + A  VDV    GP   +  LK  +PK++MP F +P    +GPE+D+  PK D
Sbjct: 2205 PLSADVKVQAGQVDVKLLEGPVPEEVGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKLD 2264

Query: 2077 -----VVVSGPKVDVEVP--DVSLEGPEGKLKGPKLK-----------MPEMHFKAPKIS 2118
                 V V+ P V+V +P  +V ++ P  KL G +L+             +  FK PK  
Sbjct: 2265 LKDPKVEVTAPDVEVSLPSVEVDVKAPGAKLDGARLEGDMSLADKDVTAKDSKFKMPKFK 2324

Query: 2119 MPDVDLHLKGPKV---------KGDVDVSLPKLEGDL-------TGPSVDVEVP--DVEL 2160
            M    +   G  +         K + DVSLP ++GDL         PS D+EV    V++
Sbjct: 2325 MLSFGVSALGKSIEASADVSALKVEADVSLPSMQGDLKTTDLSVQPPSADLEVQAGQVDV 2384

Query: 2161 ECPDA-------------KLKGPKFKMPEMHFKTPKISMPDVNLNLKGPK---VKGDMDV 2204
            + P+              KL+ P FKMP++  K P+I +    L+LKGPK   +  D++V
Sbjct: 2385 KLPEGPVPEGAGLKGHLPKLQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKTDVMAPDVEV 2444

Query: 2205 SVPKVEGEMKVPDVDIRGP--KVDIDAPDVDVHGPDWHLKMPKMKMPKF--SMPGFKGEG 2260
            S P VE +++ P   + G   + D+   D DV   D   K+PK KMP F  S PG K   
Sbjct: 2445 SQPSVEVDVEAPGAKLDGAWLEGDLSVADKDVTTKDSRFKIPKFKMPSFGVSAPG-KSIE 2503

Query: 2261 PEVDVNLPK-------------------------ADVDVSGPKVDVEVPD------VSLE 2289
              VDV+ PK                         AD++V   +VDV++P+        L+
Sbjct: 2504 ASVDVSAPKVEADGSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGLK 2563

Query: 2290 GPEGKLKGPKFKMPEMHFKTPKISMPDVDFNLKGPKIK---GDVDVSAPKLEGELKGPEL 2346
            G   K++ P FKMPEM  K P++ +     +LKGPK +    DV++S   +E +++ P  
Sbjct: 2564 GHLPKVQMPSFKMPEMDLKGPQLDVKGPKLDLKGPKAEVTAPDVEMSLSSMEVDVQAPRA 2623

Query: 2347 DVKGPKLDAD--MPEVAVEGPNGKWKTPKFKMPDMHFKAP-----------------KIS 2387
             + G +L+ D  + +  V   + K+K PKFKMP     AP                  +S
Sbjct: 2624 KLDGARLEGDLSLADKGVTAKDSKFKMPKFKMPSFRVSAPGESIEALVDVSELKVEADMS 2683

Query: 2388 MPDL-------DLHLKSPKAK-----GEVDVDVPK--------LEG-------------- 2413
            +P +       D+ ++ P A+     G+VDV +P+        L+G              
Sbjct: 2684 LPSMQGDLKTTDISIQPPSAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKLQMPSFKMPE 2743

Query: 2414 -DLKGPHVDVSGPDIDIEGPEGKLKGPKFKM----------------------------- 2443
             DLKGP +DV GP++D++GP+ ++  P  KM                             
Sbjct: 2744 VDLKGPQIDVKGPNVDLKGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLAD 2803

Query: 2444 -----PDMHFKAPNISMPDVDLNLKGPKIKGDVDV---------SVPEVEGKLEVPDMNI 2489
                  D  FK P   MP   ++  G  I+  VDV         S P ++G L+  D+ I
Sbjct: 2804 KGMTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSELKVEADGSFPSMQGDLKTTDIRI 2863

Query: 2490 RGP----KVDVNAPDVQAPDWHL--------KMPKMKMPKFSMPGFKAEGPEVDVNLPKA 2537
            + P    +V     DV+ P+ H+         +PK++MP F MP    +GP++DV  PK 
Sbjct: 2864 QPPSAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPK- 2922

Query: 2538 DVDISGPKVDIEGPD---------VNIEGPEGKLKGPKLK-----------MPEMNIKAP 2577
             +D+ GPK ++  PD         V++E P  KL G +L+             +   K P
Sbjct: 2923 -LDLKGPKAEVTAPDVEVSLPSVEVDVEAPRAKLDGARLEGDLSLADKDVTAKDSKFKMP 2981

Query: 2578 KISMPDFDLHLKGPKVKGDVDVSLPKVE---------GDLKGPEVDIKGP--KVDINAPD 2626
            K  MP F +   G  ++  VDVS PKVE         GDLK  ++ I+ P  ++++ A  
Sbjct: 2982 KFKMPSFGVSAPGKSIEVSVDVSAPKVEAEVSLPSMQGDLKTTDISIEPPSAQLEVQAGQ 3041

Query: 2627 VGVQGPDWHL--------KMPKVKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPKVDIEG 2678
            V ++ P+ H+         +PK++MP F MP    +GP  DVK PK  +D+ GPK D+  
Sbjct: 3042 VDLKLPEGHVPEGAGLKGHLPKLQMPSFKMPKVDRKGPQIDVKGPK--LDLKGPKTDVTA 3099

Query: 2679 PDVNIEGP--------------------------------EGKLKGPKFKMPEMNIKAPK 2706
            PDV +  P                                + K K PKFKMP   + AP 
Sbjct: 3100 PDVEVSQPGMEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPG 3159

Query: 2707 ISMPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGP--KVDIDAPDVDVHGPDWHL 2764
             S+ ++ +++  PKV  + D+SLP ++GDLK  ++ I+ P  ++++ A  VDV  P+ H+
Sbjct: 3160 KSI-EVLVDVSAPKV--EADLSLPSMQGDLKNTDISIEPPSAQLEVQAGQVDVKLPEGHV 3216

Query: 2765 --------KMPKIKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGP-- 2814
                     +PK++MP   MP    +GP +D+  PK  +D+ GPK+DV  PDV +  P  
Sbjct: 3217 LEGAGLKGHLPKLQMPSFKMPKVDRKGPQIDIKGPK--LDLKGPKMDVTAPDVEVSQPSM 3274

Query: 2815 ------------------------------EGKWKSPKFKMPEMHFKTPKISMPDIDLNL 2844
                                          + K+K PKFKMP      P  S+    +++
Sbjct: 3275 EVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSYRASAPGKSI-QASVDV 3333

Query: 2845 TGPKIKGDVDVTGPKVEGDLKGPEVDLKGPKVDIDVP--DVNVQGPDWHL--------KM 2894
            + PK + DV +  P ++GDLK  ++ ++ P VD++V    V+V+ P+ H+         +
Sbjct: 3334 SAPKAEADVSL--PSMQGDLKTTDLSIQLPSVDLEVQAGQVDVKLPEGHVPEGAGLKGHL 3391

Query: 2895 PKMKMPKFSMPGFKAEGPEVDVNLPKADVDVSGPKVDVEGPD---------VNIEGPEGK 2945
            PK++MP F MP    + P+VD+  PK D+ V  PK +V  PD         V+++ P  K
Sbjct: 3392 PKVEMPSFKMPKVDLKSPQVDIKGPKLDLKV--PKAEVTVPDVEVSLPSVEVDVQAPRAK 3449

Query: 2946 LKGPKFK-----------MPEMNIKAPKIPMPDFDLHLKGPKVKGDVDISLPKVE----- 2989
            L G + +             +   K PK  MP F +   G  ++  +D+S PKVE     
Sbjct: 3450 LDGARLEGDLSLAEKDVTAKDSKFKMPKFKMPSFGVSAPGRSIEASLDVSAPKVEADVSL 3509

Query: 2990 ----GDLKGPEVDIRGPQVDIDVPDVGV----------QGPDWHLKMPKVKMPKFSMPGF 3035
                GDLK  ++ I+ P  D++V  V V          +G      +PKV+MP    P  
Sbjct: 3510 SSMQGDLKATDLSIQPPSADLEVQAVQVDVELLEGPVPEGAGLKGHLPKVEMPSLKTPKV 3569

Query: 3036 KGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGP------------------------- 3070
              +GP +DV  PK  LD+ GPK ++ VPDV +  P                         
Sbjct: 3570 DLKGPQIDVKGPK--LDLKGPKAEVRVPDVEVSLPSVEVDVQAPKAKLDAGRLEGDLSLA 3627

Query: 3071 -------EGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMKVP 3123
                   + K K PKFKMP   + AP  SM +  +++  PKV  + DVSLP ++GD+K  
Sbjct: 3628 DKDVTAKDSKFKMPKFKMPSFRVSAPGKSM-EASVDVSAPKV--EADVSLPSMQGDLKTT 3684

Query: 3124 DVDIKGPKVD--INAPDVDVQGPDWHL--------KMPKIKMPKISMPGFKGEGPEVDVN 3173
            D+ I+ P  D  + A  +DV+ P+  +         +PK++MP + MP    +GP+VD+ 
Sbjct: 3685 DLSIQPPSADLKVQAGQMDVKLPEGQVPEGAGLKEHLPKVEMPSLKMPKVDLKGPQVDIK 3744

Query: 3174 LPKADL-----DVSGPKVDVDVPDVNIE-------------------------GPDAKLK 3203
             PK DL     +V+ P V+V +P V ++                           D+K K
Sbjct: 3745 GPKLDLKVSKAEVTAPDVEVSLPSVEVDVQAPRAKLDSAQLEGDLSLADKDVTAKDSKFK 3804

Query: 3204 GPKFKMPEMNIKAPKISMPDLDLNLKGPKMKGEVDVSLANVEGDLKGPALDIKGPKID-- 3261
             PKFKMP   + AP  S+ +  +++  PK+  E DVSL +++GDLK   L I+    D  
Sbjct: 3805 MPKFKMPSFGVSAPGKSI-EASVHVSAPKV--EADVSLPSMQGDLKTTDLSIQPHSADLT 3861

Query: 3262 VDAPDIDI-----HGP-DAKLKG--PKLKMPDMHVNMPKISMPEIDLNLKGSKL------ 3307
            V A  +D+     H P +A LKG  PK++MP     MPK+ +   ++++KG KL      
Sbjct: 3862 VQARQVDMKLLEGHVPEEAGLKGHLPKVQMPSF--KMPKVDLKGPEIDIKGPKLDLKDPK 3919

Query: 3308 ----KGDVDVSGPKLEGDIKAPSLDIKGPEVDVSGPKLNIEGKSKKSRFKLPKFNFSGSK 3363
                  DV+VS P +E D++AP   + G  ++      + +  +K S+FK+PKF      
Sbjct: 3920 VEVTAPDVEVSLPSVEVDVEAPGAKLDGARLEGDLSLADKDMTAKDSKFKMPKFKMPSFG 3979

Query: 3364 VQTPEVDVKGKKPDIDITGPKVDINAPDVEVQGKVKGSKFKMPFLSISSPKVSMPDVELN 3423
            V  P    K  +  +D+T PKV+ +     +QG +K +             V  P  +L 
Sbjct: 3980 VSAPG---KSMEASVDVTAPKVEADVSLPSMQGDLKATDL----------SVQPPSADLE 4026

Query: 3424 LKSPKVKGDLDIAGPNLEG-DFKG--PKVDI---KAPEVNLNAPDVDVHGPDWNLKMPKM 3477
            +++ +V   L   GP  EG   KG  PKV +   K P+V+L  P +DV GP  +LK PK 
Sbjct: 4027 VQAGQVDVKLP-EGPVPEGASLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKA 4085

Query: 3478 KMPKFSVSGLKAEGPDVAVDLPKGDINIEGPSMNIEG---------PDLNVEGPEGGLKG 3528
            ++            PDV + L   +++++ P   ++G          D +V   +   K 
Sbjct: 4086 EV----------TAPDVKMSLSSMEVDVQAPRAKLDGVQLEGDLSLADKDVTAKDSKFKM 4135

Query: 3529 PKFKMPDMNIKAPKISMPDIDLNLKGPKVKGDVDISLPKLEGDLKGPEVDIKGPKVD--I 3586
            PKFKMP   + AP  SM   + ++   ++K   D+SLP ++GDLK  ++ I+ P  D  +
Sbjct: 4136 PKFKMPSFGVSAPGKSM---EASVDVSELKAKADVSLPSMQGDLKTTDLSIQSPSADLEV 4192

Query: 3587 NAPDVDVHGPDWHL--------KMPKVKMPKFSMPGFKGEGPEVDVTLPKADI-----DI 3633
             A  VDV  P+  L         +PKV+MP   MP    +GP+VDV  PK D+     D+
Sbjct: 4193 QAGQVDVKLPEGPLPKGAGLKGHLPKVQMPCLKMPKVALKGPQVDVKGPKLDLKGPKADV 4252

Query: 3634 SGPNVDVDVP--DVNIEGP-----------------------DAKLKGPKFKMPEMNIKA 3668
              P V+V +P  +V++E P                       D+K K PKFKMP   + A
Sbjct: 4253 MTPVVEVSLPSMEVDVEAPGAKLDSVRLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSA 4312

Query: 3669 PKISMPDFDLNLKGPKMKGDVVVSLPKVEGDLKGPEVDIKGPKVDIDT------------ 3716
            P  S+ +  L++   K++ D  VSLP ++GDLK   + I+ P  D++             
Sbjct: 4313 PGKSI-EASLDVSALKVEAD--VSLPSMQGDLKTTHLSIQPPSADLEVQAGQEDVKLPEG 4369

Query: 3717 ---PDINIEGSEGKFKGPKFKIPEMHLKAPKISMPDIDLNLKGPKVK---GDVDVSLPKM 3770
                   ++G   K + P FK+P++ LK P+I +    L+LKGPKV+    ++DVSLP M
Sbjct: 4370 PVHEGAGLKGHLPKLQMPSFKVPKVDLKGPQIDVNVPKLDLKGPKVEVTSPNLDVSLPSM 4429

Query: 3771 EGDLKGPEVDIKGPKV--DINAPDVDVQGPDWHLKMPKVKMPKFSM--PGFKGEGPDVDV 3826
            E D++ P   +   ++  D++  D DV   D   KMPK KMP F M  PG K     VDV
Sbjct: 4430 EVDIQAPGAKLDSTRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGMLSPG-KSIEVSVDV 4488

Query: 3827 NLPKADLDVSGPKV--DIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKG 3884
            + PK + D+S P +  D+   D+ I+ P   L   + +  ++++K P+  MP++   LKG
Sbjct: 4489 SAPKMEADMSIPSMQGDLKTTDLRIQAPSADL---EVQAGQVDLKLPEGHMPEV-AGLKG 4544

Query: 3885 PKVKGDM-DVSLPKVEGDMQVPDLDIKGPKVDINAPDVDVRGPDWHLKMPKIKMPKISMP 3943
               K +M    +PKV  D++ P +D+KGPK+D+  P  +V  PD  + +P +        
Sbjct: 4545 HLPKVEMPSFKMPKV--DLKGPQVDVKGPKLDLKGPKAEVMAPDVEVSLPSV-------- 4594

Query: 3944 GFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISM 4003
                   E DV  P + LD +  + D+ +   ++ G D+K +GPK         + K+SM
Sbjct: 4595 -------ETDVQAPGSMLDGARLEGDLSLAHEDVAGKDSKFQGPKLSTSGFEWSSKKVSM 4647

Query: 4004 PDFDLH-----------------------LKGPKVKGDVDVSLPKMEGDLKAPEVDIKGP 4040
               ++                        L  P   G++ +++ ++  D K  ++  K P
Sbjct: 4648 SSSEIEGNVTFHEKTSTFPIVESVVHEGDLHDPSRDGNLGLAVGEVGMDSKFKKLHFKVP 4707

Query: 4041 KVDIDA----PDVDVHGPDWHLKM-----------------------PKVKMPKFSMPGF 4073
            KV   +     D  V G    + +                       P ++MPK    GF
Sbjct: 4708 KVSFSSTKTPKDSLVPGAKSSIGLSTIPLSSSECSSFELQQVSACSEPSMQMPKVGFAGF 4767

Query: 4074 KGE--------------GPEVDVNLPKADIDV--------------SGPKVDIDTP---- 4101
                              P  DV L K  + V              SG + DI  P    
Sbjct: 4768 PSSRLDLTGPHFESSILSPCEDVTLTKYQVTVPRAALAPELALEIPSGSQADIPLPKTEC 4827

Query: 4102 DIDIHGPE----------------------GKLKGPKFKMPDLHLKAPKISMPEVDLN-- 4137
              D+  PE                      G++  PKF  P      P++++PE DL+  
Sbjct: 4828 STDLQPPEGVPTSQAESHSGPLNSMIPVSLGQVSFPKFYKPKFVFSVPQMAVPEGDLHAA 4887

Query: 4138 ----LKGPKMKGD-VDVSLPKVEGD------LKGPEVDIKGPKVDIDVP------DVDVQ 4180
                +  P   G+ V   LP  +         +GPE  +   +  +  P      D D +
Sbjct: 4888 VGAPVMSPLSPGERVQCPLPSTQLPSPGTCVSQGPEELVASLQTSVVAPGEAPSEDADHE 4947

Query: 4181 GPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVS--------GPK--VDIDVPD 4230
            G    LKMPK+K+P F     K  GP VD      D  +S         P+  + +D+P 
Sbjct: 4948 GKGSPLKMPKIKLPSFRWSPKKETGPKVDPECSVEDSKLSLVLDKDEVAPQSAIHMDLPP 5007

Query: 4231 VNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPE 4290
               +G   +   P F MP++ +   K S     L    P+   D  +S     G  +  E
Sbjct: 5008 ER-DGEKGRSTKPGFAMPKLALPKMKASKSGVSL----PQRDVDPSLSSATAGGSFQDTE 5062

Query: 4291 -VDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPK--FSMPGFKGEGPDVDVTLPKADIEI 4347
                 G +  + A          +L  P+V +P   F+ P         D+   KA +E+
Sbjct: 5063 KASSDGGRGGLGATASATGSEGVNLHRPQVHIPSLGFAKP---------DLRSSKAKVEV 5113

Query: 4348 SGPKVDIDAP--DVSIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDFNLKGPKVKGDVDV 4405
            S P+ D+  P  D+S EG D++  G                              GDV V
Sbjct: 5114 SQPEADLPLPKHDLSTEG-DSRGCG-----------------------------LGDVPV 5143

Query: 4406 SLPKVEGDLKGPEIDIKGPSLDIDTPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDFD 4465
            S P  EG    PE  ++      D   + +E PE +    K+   E   K PK  MP   
Sbjct: 5144 SQPCGEGIAPTPEDPLQPSCRKPDAEVLTVESPEEEAM-TKYSQ-ESWFKMPKFRMPSLR 5201

Query: 4466 LHLKGPKVKGDVDVSLPKVESDLKGPEVDIEGPEGKLKGPKFKMPDVHFKSPQISMSDID 4525
               +     G ++V+  +  +          G E   K  +F           +S S+++
Sbjct: 5202 RSFRDRGGAGKLEVAQTQAPA--------ATGGEAAAKVKEF----------LVSGSNVE 5243

Query: 4526 --LNLKGPKIKGDMDISVPKLEGDLKGPKVDVKGPKV----------GIDTPDIDIHGPE 4573
              ++L+ P+   ++  S  K   D+    +D  G K+           + T ++ IH  +
Sbjct: 5244 AAMSLQLPEADAEVTASESKSSTDILRCDLDSTGLKLHLSTAGMTGDELSTSEVRIHPSK 5303

Query: 4574 GKLKGPKFKMPDLHLKAPKISMPEVD---LNLKGPKVKGDMDISLPKVEGDLKGP---EV 4627
            G L    F+MP + L   ++   E+D   L+  G  +   M+    K     +GP   + 
Sbjct: 5304 GPL---PFQMPGMRLPETQVLPGEIDETPLSKPGHDL-ASMEDKTEKWSSQPEGPLKLKA 5359

Query: 4628 DIRDPKVDIDVPDVDVQGPDWHL--KMPKVKMPKFSMPGFKGEG----PDV-DVNLPKAD 4680
               D    I V +VD    D  L  K PK+ +P+FS P    E     P V +V  P+A+
Sbjct: 5360 SSTDMPSQISVVNVDQLWEDSVLTVKFPKLMVPRFSFPAPSSEDDVFIPTVREVQCPEAN 5419

Query: 4681 IDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMSIKAPKISMPDIDLNLKGPKVKGDVD 4740
            ID +  K    +   +I    A + G +     + ++AP IS   + ++++G +V+   +
Sbjct: 5420 IDTALCKESPGLWGASILKAGAGVPGEQPVDLNLPLEAPPIS--KVRVHIQGAQVESQ-E 5476

Query: 4741 VTLPKVEG----DLKGPEADIKGPKVDINTPDVDVHGPDWHLKMPKVKMPK 4787
            VT+  +      DL  P         +   P  ++  P +   + KVK+P+
Sbjct: 5477 VTIHSIVTPEFVDLSVPRTFSTQIVRESEIPTSEIQTPSYGFSLLKVKIPE 5527



 Score = 1587 bits (4110), Expect = 0.0
 Identities = 1411/4892 (28%), Positives = 2176/4892 (44%), Gaps = 1192/4892 (24%)

Query: 1559 EGKLKGPKFKMPSMNIQTHKISMPDVGLNLKAPKLKTDVDVSLPKVEGDLKGPEIDVKAP 1618
            + K K PKFKMP         SM +  +++ APK+  + DVSL  ++GDLK  ++ V+ P
Sbjct: 672  DSKFKMPKFKMPLFGASAPGKSM-EASVDVSAPKV--EADVSLLSMQGDLKTTDLSVQTP 728

Query: 1619 KMDVNVGDIDIEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDMDVSVPKV 1678
                   D++++  +  +K P+  +PE                  G  +KG +    PKV
Sbjct: 729  S-----ADLEVQDGQVDVKLPEGPLPE------------------GASLKGHL----PKV 761

Query: 1679 EG-EMKVPDVDIKGPKVDIDAPDVEVHDPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLP 1737
            +   +K+P VD+KGPK+D+  P  EV  PD  + +  M               EVDV  P
Sbjct: 762  QRPSLKMPKVDLKGPKLDLKGPKAEVTAPDVKMSLSSM---------------EVDVQAP 806

Query: 1738 KADIDVSGPSVDTDAPDLDIEGPEGKLKGSKFKMPKLNIKAPKVSMPDVDLNLKGPKLKG 1797
            +A +D +    D    D ++   + K K  KFKMP   + AP  SM D  +++  PK+  
Sbjct: 807  RAKLDGARLEGDLSLADKEVTAKDSKFKMPKFKMPSFGVSAPGKSMED-SVDVSAPKV-- 863

Query: 1798 EIDASVPELEGDLRGPQVDVKGPFVEAEVP--DVDLECPDA-------------KLKGPK 1842
            E D S+  ++GDL+   + ++ P  + EV    VD++ P+              K++ P 
Sbjct: 864  EADVSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGPKVHLPKVEMPS 923

Query: 1843 FKMPEMHFKAPKISMPDVDLHLKGPKVK---GDADVSVPKLEGDLTGPSVGVE------- 1892
            FKMP++  K P+I +    L LKGPK +    D +VS+P +E D+      ++       
Sbjct: 924  FKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDGEVSLPSMEVDVQAQKAKLDGAWLEGD 983

Query: 1893 --VPDVELECPDAKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDVDVSVPKLEGD 1950
              + D ++   D+K K PKFKMP     AP            G  +K  VDVS PK+E D
Sbjct: 984  LSLADKDVTAKDSKFKMPKFKMPSFGVSAP------------GKSIKALVDVSAPKVEAD 1031

Query: 1951 LTGPSVG------------------VEVPDVELECPD------AKLKG-------PKFKM 1979
            L+ PS+                   V+   V+++ P+      A LKG       P FKM
Sbjct: 1032 LSLPSMQGDLKTTDLSIQPASTDLKVQADQVDVKLPEGHLPEGAGLKGHLPKVEMPSFKM 1091

Query: 1980 PEMHFKTPKISMPDVDLHLKGPKVK---GDMDVSVPKVEGEMKVPDVDIKGPKMD--IDA 2034
            P++  K P++ +    L LK PK +    D++VS+P VE +++ P   +   +++  +  
Sbjct: 1092 PKVALKGPQVDVKGPKLDLKSPKAEVTAPDVEVSLPSVEVDVEAPGAKLDSARLEGELSL 1151

Query: 2035 PDVDVHGPDWHLKMPKMKMPKF--SMPGFKAEGPEVDVNLPKADVVVSGPKV--DVEVPD 2090
             D DV   D   KMPK KMP F  S PG   E   VDV+ PK +  VS P +  D++  D
Sbjct: 1152 ADKDVTAKDSRFKMPKFKMPSFGASAPGKSIEA-SVDVSAPKVEADVSLPSMQGDLKTTD 1210

Query: 2091 VS-------------------LEG--PEG--------KLKGPKLKMPEMHFKAPKISMPD 2121
            +S                   LEG  PEG        K++ P LKMP++  K P++ +  
Sbjct: 1211 LSIQPPSADLEVHAGQVDVKLLEGHVPEGAGFKGHLPKVQMPSLKMPKVDLKGPQVEVRG 1270

Query: 2122 VDLHLKGPKVK---GDVDVSLPKLEGDLTGPSV---------DVEVPDVELECPDAKLKG 2169
              L LKG K +    +V VSLP +E D+  P           D+ + D ++   D+K K 
Sbjct: 1271 PKLDLKGHKAEVTAHEVAVSLPSVEVDMQAPGAKLDGAQLDGDLSLADKDVTAKDSKFKM 1330

Query: 2170 PKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMDVSVPKVEGEMKVPDVDIRGPKVDID- 2228
            PKFKMP      P  S+ + +++L  PKV+ DM  S+P ++G++K  D+ I+ P  D++ 
Sbjct: 1331 PKFKMPSFGVSAPGKSI-EASVDLSAPKVEADM--SLPSMQGDLKTTDLSIQPPSTDLEL 1387

Query: 2229 -APDVDVHGPDWHLK--------MPKMKMPKFSMPGFKGEGPEVDVNLPKAD-----VDV 2274
             A  +DV  P+  +         +PK++MP F +P    +GPE+D+  PK D     V+V
Sbjct: 1388 QAGQLDVKLPEGPVPEGAGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKLDLKDPKVEV 1447

Query: 2275 SGPKVDVEVP--DVSLEGPEGKLKGPKFK-----------MPEMHFKTPKISMPDVDFNL 2321
            + P V+V +P  +V +E P  KL G + +             +  FK PK  MP    + 
Sbjct: 1448 TAPDVEVSLPSVEVDVEAPGAKLDGGRLEEDMSLADKDLTTKDSKFKMPKFKMPSFGVSA 1507

Query: 2322 KGPKIKGDVDVSAPKLE---------GELKGPELDVKGPKLDADMP--EVAVEGPNG--- 2367
             G  I+  VDVSAPK+E         G+LK  +L ++ P  D ++   +V V+ P G   
Sbjct: 1508 PGKSIEASVDVSAPKVEADVSLPSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVS 1567

Query: 2368 ----------KWKTPKFKMPDMHFKAPKISMPDLDLHLKSPKAKG------------EVD 2405
                      K + P FKMP +  K P+I +    L LK PK +             EVD
Sbjct: 1568 EGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKVEVTAPDVKMSLSSMEVD 1627

Query: 2406 VDVPKLEGDLKGPHVDVSGPDIDIEGPEGKLKGPKFKMPDMHFKAPNISMPDVDLNLKGP 2465
            V  P+ + D      D+S  D  +   + K K PKFKMP     AP  S+ +  +++  P
Sbjct: 1628 VQAPRAKLDGAQLEGDLSLADKAVTAKDSKFKMPKFKMPSFGVSAPGKSI-EASVDVSEP 1686

Query: 2466 KIKGDVDVSVPEVEGKLEVPDMNIRGPKVDVNAP----DVQAPDWHLK--------MPKM 2513
            K+  + DVS+P ++G L+  D++I+ P  D+       +V+ P+  L         +PK+
Sbjct: 1687 KV--EADVSLPSMQGDLKTTDLSIQSPSADLEVQAGQVNVKLPEGPLPEGAGFKGHLPKV 1744

Query: 2514 KMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDIEGPDV---------NIEGPEGKLKG 2564
            +MP   MP    +GP++DV  PK  +D+ GPK ++  PDV         ++E P  KL  
Sbjct: 1745 QMPSLKMPKVALKGPQMDVKGPK--LDLKGPKAEVMAPDVEVSLPSVEVDVEAPGAKLDS 1802

Query: 2565 PKLK-----------MPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVE-------- 2605
             +L+             +   K PK  MP F +   G  ++  VDVS PKVE        
Sbjct: 1803 VRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSAPKVEAEVSLPSM 1862

Query: 2606 -GDLKGPEVDIKGPKVD--INAPDVGVQGPDWHLK--------MPKVKMPKFSMPGFKGE 2654
             GDLK  ++ I  P  D  + A  V ++ P+  +         +PKV MP F MP    +
Sbjct: 1863 QGDLKTTDLCIPLPSADLVVQAGQVDMKLPEGQVPEGAGLKGHLPKVDMPSFKMPKVDLK 1922

Query: 2655 GPDGDVKLPKADIDVSGPKVDIEGPDVNIEGP---------------------------- 2686
            GP  DVK   A +D+ GPK ++  PDV +  P                            
Sbjct: 1923 GPQTDVK--GAKLDLKGPKAEVTAPDVEVSLPSMEVDVQAQKAKLDGARLEGDLSLADKD 1980

Query: 2687 ----EGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVD 2742
                + K K PKFKMP   + AP  S+ +  +++  PKV  + DVSLP ++GDLK  ++ 
Sbjct: 1981 MTAKDSKFKMPKFKMPSFGVSAPGRSI-EASVDVPAPKV--EADVSLPSMQGDLKTTDLS 2037

Query: 2743 IKGPKVD--IDAPDVDVHGPDWHLK--------MPKIKMPKISMPGFKGEGPDVDVNLPK 2792
            I+ P  D  +    VDV  P+ H+         +PK++MP + MP    +GP VD+  PK
Sbjct: 2038 IQPPSADLKVQTGQVDVKLPEGHVPEGAGLKGHLPKVEMPSLKMPKVDLKGPQVDIKGPK 2097

Query: 2793 ADIDVSGPKVDVECPDVNIEGP--EGKWKSPKFKMPEMH------------------FKT 2832
              +D+  PKV++  PDV +  P  E   ++P+ K+   H                  FK 
Sbjct: 2098 --LDLKDPKVEMRVPDVEVSLPSMEVDVQAPRAKLDSAHLQGDLTLANKDLTTKDSKFKM 2155

Query: 2833 PKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPEV--DLKGPKVDIDV--PDVNVQGP 2888
            PK  MP   ++  G  I+  VDV+ PKVE D+  P +  DLK   + I     DV VQ  
Sbjct: 2156 PKFKMPSFGVSAPGKSIEASVDVSPPKVEADMSLPSMQGDLKTTDLSIQPLSADVKVQAG 2215

Query: 2889 DWHLKM---------------PKMKMPKFSMPGFKAEGPEVDVNLPKAD-----VDVSGP 2928
               +K+               PK++MP F +P    +GPE+D+  PK D     V+V+ P
Sbjct: 2216 QVDVKLLEGPVPEEVGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKLDLKDPKVEVTAP 2275

Query: 2929 KVDVEGP--DVNIEGPEGKLKGPKFK-----------MPEMNIKAPKIPMPDFDLHLKGP 2975
             V+V  P  +V+++ P  KL G + +             +   K PK  M  F +   G 
Sbjct: 2276 DVEVSLPSVEVDVKAPGAKLDGARLEGDMSLADKDVTAKDSKFKMPKFKMLSFGVSALGK 2335

Query: 2976 KV---------KGDVDISLPKVEGDLKGPEVDIRGP---------QVDIDVPDVGV-QGP 3016
             +         K + D+SLP ++GDLK  ++ ++ P         QVD+ +P+  V +G 
Sbjct: 2336 SIEASADVSALKVEADVSLPSMQGDLKTTDLSVQPPSADLEVQAGQVDVKLPEGPVPEGA 2395

Query: 3017 DWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDV---------NI 3067
                 +PK++MP F MP    +GP +DV  PK  LD+ GPK D+  PDV         ++
Sbjct: 2396 GLKGHLPKLQMPSFKMPKVDLKGPQIDVKGPK--LDLKGPKTDVMAPDVEVSQPSVEVDV 2453

Query: 3068 EGPEGKLKGPKFK-----------MPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKV 3116
            E P  KL G   +             +   K PK  MP   ++  G  ++  +DVS PKV
Sbjct: 2454 EAPGAKLDGAWLEGDLSVADKDVTTKDSRFKIPKFKMPSFGVSAPGKSIEASVDVSAPKV 2513

Query: 3117 E---------GDMKVPDVDIKGPKVD--INAPDVDVQGPDWHLK--------MPKIKMPK 3157
            E         GD+K  D+ I+ P  D  + A  VDV+ P+  +         +PK++MP 
Sbjct: 2514 EADGSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGLKGHLPKVQMPS 2573

Query: 3158 ISMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDV---------NIEGPDAKLKG---- 3204
              MP    +GP++DV  PK  LD+ GPK +V  PDV         +++ P AKL G    
Sbjct: 2574 FKMPEMDLKGPQLDVKGPK--LDLKGPKAEVTAPDVEMSLSSMEVDVQAPRAKLDGARLE 2631

Query: 3205 -------------------PKFKMPEMNIKAPKISMPDLDLNLKGPKMKGEVDVSLANVE 3245
                               PKFKMP   + AP  S+  L   +   ++K E D+SL +++
Sbjct: 2632 GDLSLADKGVTAKDSKFKMPKFKMPSFRVSAPGESIEAL---VDVSELKVEADMSLPSMQ 2688

Query: 3246 GDLKGPALDIKGP--KIDVDAPDIDIHGPDAKL-KGPKLKMPDMHVNMPKISMPEIDLNL 3302
            GDLK   + I+ P  +++V A  +D+  P+  + +G  LK     + MP   MPE+DL  
Sbjct: 2689 GDLKTTDISIQPPSAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKLQMPSFKMPEVDLKG 2748

Query: 3303 KGSKLKG-DVDVSGPKLEGDIKAPSLDIKGPEVDVSGPKLNIEGK--------------S 3347
                +KG +VD+ GPK E       + +   EVDV  P+  ++G               +
Sbjct: 2749 PQIDVKGPNVDLKGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGMTA 2808

Query: 3348 KKSRFKLPKFNFSGSKVQTP------EVDVKGKKPDIDITGPKV--DINAPDVEVQG--- 3396
            K S+FK+PKF      V  P       VDV   K + D + P +  D+   D+ +Q    
Sbjct: 2809 KDSKFKMPKFKMPSFGVSAPGKSIEASVDVSELKVEADGSFPSMQGDLKTTDIRIQPPSA 2868

Query: 3397 -----------------------------KVKGSKFKMPFLSISSPKVSMPDVELNLKSP 3427
                                         KV+   FKMP + +  P++ +   +L+LK P
Sbjct: 2869 QLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGP 2928

Query: 3428 KVK---GDLDIAGPNLEGDFKGP--KVDIKAPEVNLNAPDVDVHGPDWNLKMPKMKMPKF 3482
            K +    D++++ P++E D + P  K+D    E +L+  D DV   D   KMPK KMP F
Sbjct: 2929 KAEVTAPDVEVSLPSVEVDVEAPRAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSF 2988

Query: 3483 SVSG---------------LKAEG--PDVAVDLPKGDINIEGPS--MNIEGPDLNVEGPE 3523
             VS                ++AE   P +  DL   DI+IE PS  + ++   ++++ PE
Sbjct: 2989 GVSAPGKSIEVSVDVSAPKVEAEVSLPSMQGDLKTTDISIEPPSAQLEVQAGQVDLKLPE 3048

Query: 3524 G------GLKG-------PKFKMPDMNIKAPKISMPDIDLNLKGPKVK---GDVDISLPK 3567
            G      GLKG       P FKMP ++ K P+I +    L+LKGPK      DV++S P 
Sbjct: 3049 GHVPEGAGLKGHLPKLQMPSFKMPKVDRKGPQIDVKGPKLDLKGPKTDVTAPDVEVSQPG 3108

Query: 3568 LEGDLKGPEVDIKGPKV--DINAPDVDVHGPDWHLKMPKVKMPKF--SMPGFKGEGPEVD 3623
            +E D++ P   + G ++  D++  D DV   D   KMPK KMP F  S PG K     VD
Sbjct: 3109 MEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPG-KSIEVLVD 3167

Query: 3624 VTLPKADIDISGPNVDVDVP--DVNIEGPDA----------------------------- 3652
            V+ PK + D+S P++  D+   D++IE P A                             
Sbjct: 3168 VSAPKVEADLSLPSMQGDLKNTDISIEPPSAQLEVQAGQVDVKLPEGHVLEGAGLKGHLP 3227

Query: 3653 KLKGPKFKMPEMNIKAPKISMPDFDLNLKGPKMK---GDVVVSLPKVEGDLKGPEVDIKG 3709
            KL+ P FKMP+++ K P+I +    L+LKGPKM     DV VS P +E D++ P   + G
Sbjct: 3228 KLQMPSFKMPKVDRKGPQIDIKGPKLDLKGPKMDVTAPDVEVSQPSMEVDVEAPGAKLDG 3287

Query: 3710 PKV--DIDTPDINIEGSEGKFKGPKFKIPEMHLKAPKISMPDIDLNLKGPKVKGDVDVSL 3767
             ++  D+   D ++   + KFK PKFK+P     AP  S+    +++  PK   + DVSL
Sbjct: 3288 ARLEGDLSLADKDVTAKDSKFKMPKFKMPSYRASAPGKSI-QASVDVSAPKA--EADVSL 3344

Query: 3768 PKMEGDLKGPEVDIKGPKVD--INAPDVDVQGPDWHLK--------MPKVKMPKFSMPGF 3817
            P M+GDLK  ++ I+ P VD  + A  VDV+ P+ H+         +PKV+MP F MP  
Sbjct: 3345 PSMQGDLKTTDLSIQLPSVDLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVEMPSFKMPKV 3404

Query: 3818 KGEGPDVDVNLPKADLDVSGPKVDIDVPDV---------NIEGPEGKLKG---------- 3858
              + P VD+  PK DL V  PK ++ VPDV         +++ P  KL G          
Sbjct: 3405 DLKSPQVDIKGPKLDLKV--PKAEVTVPDVEVSLPSVEVDVQAPRAKLDGARLEGDLSLA 3462

Query: 3859 -------------PKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMQVP 3905
                         PKFKMP   + AP  S+ +  L++  PKV+ D  VSL  ++GD++  
Sbjct: 3463 EKDVTAKDSKFKMPKFKMPSFGVSAPGRSI-EASLDVSAPKVEAD--VSLSSMQGDLKAT 3519

Query: 3906 DLDIKGPKVD--INAPDVDVR--------GPDWHLKMPKIKMPKISMPGFKGEGPEVDVN 3955
            DL I+ P  D  + A  VDV         G      +PK++MP +  P    +GP++DV 
Sbjct: 3520 DLSIQPPSADLEVQAVQVDVELLEGPVPEGAGLKGHLPKVEMPSLKTPKVDLKGPQIDVK 3579

Query: 3956 LPKADLDVSGPKVDVDVPDVNIEGP--------------------------------DAK 3983
             PK  LD+ GPK +V VPDV +  P                                D+K
Sbjct: 3580 GPK--LDLKGPKAEVRVPDVEVSLPSVEVDVQAPKAKLDAGRLEGDLSLADKDVTAKDSK 3637

Query: 3984 LKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKVD 4043
             K PKFKMP   + AP  SM +  + +  PKV  + DVSLP M+GDLK  ++ I+ P  D
Sbjct: 3638 FKMPKFKMPSFRVSAPGKSM-EASVDVSAPKV--EADVSLPSMQGDLKTTDLSIQPPSAD 3694

Query: 4044 --IDAPDVDVHGPDWHLK--------MPKVKMPKFSMPGFKGEGPEVDVNLPKADIDVS- 4092
              + A  +DV  P+  +         +PKV+MP   MP    +GP+VD+  PK D+ VS 
Sbjct: 3695 LKVQAGQMDVKLPEGQVPEGAGLKEHLPKVEMPSLKMPKVDLKGPQVDIKGPKLDLKVSK 3754

Query: 4093 ----GPKVDIDTP--DIDIHGPEGKL-----------------------KGPKFKMPDLH 4123
                 P V++  P  ++D+  P  KL                       K PKFKMP   
Sbjct: 3755 AEVTAPDVEVSLPSVEVDVQAPRAKLDSAQLEGDLSLADKDVTAKDSKFKMPKFKMPSFG 3814

Query: 4124 LKAPKISMPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDVP--DVDVQG 4181
            + AP  S+ E  +++  PK+  + DVSLP ++GDLK  ++ I+    D+ V    VD++ 
Sbjct: 3815 VSAPGKSI-EASVHVSAPKV--EADVSLPSMQGDLKTTDLSIQPHSADLTVQARQVDMKL 3871

Query: 4182 PDWHLK--------MPKVKMPKFSMPGFKGEGPDVDVNLPKADL-----DVSGPKVDIDV 4228
             + H+         +PKV+MP F MP    +GP++D+  PK DL     +V+ P V++ +
Sbjct: 3872 LEGHVPEEAGLKGHLPKVQMPSFKMPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSL 3931

Query: 4229 P--DVNIEGPDAKLKG-----------------------PKFKMPEMNIKAPKISMPDFD 4263
            P  +V++E P AKL G                       PKFKMP   + AP  SM +  
Sbjct: 3932 PSVEVDVEAPGAKLDGARLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGKSM-EAS 3990

Query: 4264 LHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDID--APDVDVHGPDWHLK------ 4315
            + +  PKV  + DVSLP ++GDLK  ++ ++ P  D++  A  VDV  P+  +       
Sbjct: 3991 VDVTAPKV--EADVSLPSMQGDLKATDLSVQPPSADLEVQAGQVDVKLPEGPVPEGASLK 4048

Query: 4316 --MPKVKMPKFSMPGFKGEGPDVDVTLPKADIEISGPKVDIDAP---------DVSIEGP 4364
              +PKV+MP F MP    +GP +DV  PK D++  GPK ++ AP         +V ++ P
Sbjct: 4049 GHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLK--GPKAEVTAPDVKMSLSSMEVDVQAP 4106

Query: 4365 -----------------------DAKLKGPKFKMPEMNIKAP-----------------K 4384
                                   D+K K PKFKMP   + AP                  
Sbjct: 4107 RAKLDGVQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSMEASVDVSELKAKAD 4166

Query: 4385 ISMPDI-------DFNLKGPKVK-----GDVDVSLPK----------------------- 4409
            +S+P +       D +++ P        G VDV LP+                       
Sbjct: 4167 VSLPSMQGDLKTTDLSIQSPSADLEVQAGQVDVKLPEGPLPKGAGLKGHLPKVQMPCLKM 4226

Query: 4410 -------VEGDLKGPEIDIKGPSLDIDTP---------DVNIEGPEGKL----------- 4442
                    + D+KGP++D+KGP  D+ TP         +V++E P  KL           
Sbjct: 4227 PKVALKGPQVDVKGPKLDLKGPKADVMTPVVEVSLPSMEVDVEAPGAKLDSVRLEGDLSL 4286

Query: 4443 ------------KGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVESDLKG 4490
                        K PKFKMP   + AP  S+   +  L    +K + DVSLP ++ DLK 
Sbjct: 4287 ADKDMTAKDSKFKMPKFKMPSFGVSAPGKSI---EASLDVSALKVEADVSLPSMQGDLKT 4343

Query: 4491 PEV----------------DIEGPEG-------------KLKGPKFKMPDVHFKSPQISM 4521
              +                D++ PEG             KL+ P FK+P V  K PQI +
Sbjct: 4344 THLSIQPPSADLEVQAGQEDVKLPEGPVHEGAGLKGHLPKLQMPSFKVPKVDLKGPQIDV 4403

Query: 4522 SDIDLNLKGPKIK---GDMDISVPKLEGDLKGP--KVDVKGPKVGIDTPDIDIHGPEGKL 4576
            +   L+LKGPK++    ++D+S+P +E D++ P  K+D    +  +   D D+   + K 
Sbjct: 4404 NVPKLDLKGPKVEVTSPNLDVSLPSMEVDIQAPGAKLDSTRLEGDLSLADKDVTAKDSKF 4463

Query: 4577 KGPKFKMPDLHLKAPKISMPEVDLNLKGPKVKGDMDISLPKVEGDLKGPEVDIRDPKVDI 4636
            K PKFKMP   + +P  S+ EV +++  PK++ DM  S+P ++GDLK  ++ I+ P  D+
Sbjct: 4464 KMPKFKMPSFGMLSPGKSI-EVSVDVSAPKMEADM--SIPSMQGDLKTTDLRIQAPSADL 4520

Query: 4637 DVP--DVDVQGPDWHLK--------MPKVKMPKFSMPGFKGEGPDVDVNLPKADIDVSGP 4686
            +V    VD++ P+ H+         +PKV+MP F MP    +GP VDV  PK  +D+ GP
Sbjct: 4521 EVQAGQVDLKLPEGHMPEVAGLKGHLPKVEMPSFKMPKVDLKGPQVDVKGPK--LDLKGP 4578

Query: 4687 KVDVDVPDVNIE--------------------------------GPDAKLKGPKFKMPEM 4714
            K +V  PDV +                                 G D+K +GPK      
Sbjct: 4579 KAEVMAPDVEVSLPSVETDVQAPGSMLDGARLEGDLSLAHEDVAGKDSKFQGPKLSTSGF 4638

Query: 4715 SIKAPKISMPDIDL-----------------------NLKGPKVKGDVDVTLPKVEGDLK 4751
               + K+SM   ++                       +L  P   G++ + + +V  D K
Sbjct: 4639 EWSSKKVSMSSSEIEGNVTFHEKTSTFPIVESVVHEGDLHDPSRDGNLGLAVGEVGMDSK 4698

Query: 4752 GPEADIKGPKVDIN---TP-DVDVHGPDWHLKM-----------------------PKVK 4784
              +   K PKV  +   TP D  V G    + +                       P ++
Sbjct: 4699 FKKLHFKVPKVSFSSTKTPKDSLVPGAKSSIGLSTIPLSSSECSSFELQQVSACSEPSMQ 4758

Query: 4785 MPKFSMPGFKGEGPDVDVSLPKADIDVSGPKVDVDIPDVNIEGPDAKLKGPKFKMPEINI 4844
            MPK    GF      +D++ P  +  +  P  DV +    +  P A L       PE+ +
Sbjct: 4759 MPKVGFAGFPSSR--LDLTGPHFESSILSPCEDVTLTKYQVTVPRAALA------PELAL 4810

Query: 4845 KAPKISIPDVDLDLKGPKVKGDFDVSVPKVEGTLKGPEVDLKGPRLDFEGPDA--KLSGP 4902
            + P  S  D+ L    PK +   D+  P  EG          GP L+   P +  ++S P
Sbjct: 4811 EIPSGSQADIPL----PKTECSTDLQPP--EGVPTSQAESHSGP-LNSMIPVSLGQVSFP 4863

Query: 4903 SLKMPSLEISAPKVTAPDVDLHLKAPKIGFSGPKLEGGEVDLKGPKVEAPS--------- 4953
                P    S P++  P+ DLH  A       P   G  V    P  + PS         
Sbjct: 4864 KFYKPKFVFSVPQMAVPEGDLHA-AVGAPVMSPLSPGERVQCPLPSTQLPSPGTCVSQGP 4922

Query: 4954 ------LDVHMDSP--------DINIEGPDVKIPKFKKPKFGFGAKS-------PKADIK 4992
                  L   + +P        D   +G  +K+PK K P F +  K        P+  ++
Sbjct: 4923 EELVASLQTSVVAPGEAPSEDADHEGKGSPLKMPKIKLPSFRWSPKKETGPKVDPECSVE 4982

Query: 4993 SPSL------DVTVPEAELNLETPEISVGGKGKKSK--FKMPKIHMSGPKIKAKKQGFDL 5044
               L      D   P++ ++++ P    G KG+ +K  F MPK+ +  PK+KA K G  L
Sbjct: 4983 DSKLSLVLDKDEVAPQSAIHMDLPPERDGEKGRSTKPGFAMPKLAL--PKMKASKSGVSL 5040

Query: 5045 NVPGGEIDASLKAPDV-----DVNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEFDIKS 5099
              P  ++D SL +        D   A  D        +     +    ++ P V   I S
Sbjct: 5041 --PQRDVDPSLSSATAGGSFQDTEKASSDGGRGGLGATASATGSEGVNLHRPQVH--IPS 5096

Query: 5100 PKFKAEAPLPSPKLEGELQAPDLELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGDL 5159
              F A+  L S K + E+  P+ +L LP      L  +  +    + DV +S P  EG  
Sbjct: 5097 LGF-AKPDLRSSKAKVEVSQPEADLPLPK---HDLSTEGDSRGCGLGDVPVSQPCGEGIA 5152

Query: 5160 KGPK--VQANLGAPD---INIEGLDAKVKTP---SFGISAPQVSIPDVNVNLKGPKIKGD 5211
              P+  +Q +   PD   + +E  + +  T          P+  +P +  + +     G 
Sbjct: 5153 PTPEDPLQPSCRKPDAEVLTVESPEEEAMTKYSQESWFKMPKFRMPSLRRSFRDRGGAGK 5212

Query: 5212 VPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDV 5271
            +     + P     G EA  K  +F      + G  +E   A +  QLP  + ++   + 
Sbjct: 5213 LEVAQTQAPAAT--GGEAAAKVKEFL-----VSGSNVE---AAMSLQLPEADAEVTASES 5262

Query: 5272 KLEGP----DVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAP 5327
            K        D+   G  + L +  ++  ++S  ++ ++   PS KG L   +P M++   
Sbjct: 5263 KSSTDILRCDLDSTGLKLHLSTAGMTGDELSTSEVRIH---PS-KGPLPFQMPGMRLPET 5318

Query: 5328 GLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSV 5387
             + L G   +  +   G  +  ++  T+     P+  L+  +   D+         ++SV
Sbjct: 5319 QV-LPGEIDETPLSKPGHDLASMEDKTEKWSSQPEGPLKLKASSTDMP-------SQISV 5370

Query: 5388 GAPDLSLEASEGSIKLPKMKLPQFGISTPGSD 5419
               D   E S  ++K PK+ +P+F    P S+
Sbjct: 5371 VNVDQLWEDSVLTVKFPKLMVPRFSFPAPSSE 5402



 Score = 1583 bits (4100), Expect = 0.0
 Identities = 1456/5128 (28%), Positives = 2251/5128 (43%), Gaps = 1288/5128 (25%)

Query: 1723 PGFKAEGPEVDVNLPKADIDVSGPSV-DTDAPDLDIEGPEGKLKGSKFKMPKLNIKAPKV 1781
            PG   EG      L   +I ++  S+ DT      I  PE +++    K PK      K 
Sbjct: 444  PGMSREGE--GEGLQSLEIGIARLSLRDTTEGGTQIGPPEIRVRVHDLKTPKFAFSTEKE 501

Query: 1782 SMPDVDLNLKGPKLKGEIDASVPELEGDLRGPQVDVKG------PFVEAEVP-------- 1827
              P+ +  L  P+     DAS     G L+G +V+  G      P   AE          
Sbjct: 502  --PERERRLSTPQRGKRQDASSKAGTG-LKGEEVEGAGWMPGREPTTHAEAQGDEGDGEE 558

Query: 1828 -----------DVDLECPDAKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDADVS 1876
                       D   E  + +++ PKFK+P + +   K        H K  + K   D  
Sbjct: 559  GLQRTRITEEQDKGREDTEGQIRMPKFKIPSLGWSPSK--------HTKTGREKATEDTE 610

Query: 1877 VPKLEGDLTGPSVGVE-------------------------------------VPDVELE 1899
              + EG+ T  +   E                                     + + E+ 
Sbjct: 611  QGR-EGEATATADRREQRRTEEGLKDKEDSDSMTNTTKIQLIHDEKRLKKEQILTEKEVA 669

Query: 1900 CPDAKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDVDVSVPKLEGDLTGPSVGVE 1959
              D+K K PKFKMP     AP  SM +  + +  PKV  + DVS+  ++GDL    + V+
Sbjct: 670  TKDSKFKMPKFKMPLFGASAPGKSM-EASVDVSAPKV--EADVSLLSMQGDLKTTDLSVQ 726

Query: 1960 VPDVELECPD---------------AKLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVK 2004
             P  +LE  D               A LKG   K+     K PK+ +    L LKGPK +
Sbjct: 727  TPSADLEVQDGQVDVKLPEGPLPEGASLKGHLPKVQRPSLKMPKVDLKGPKLDLKGPKAE 786

Query: 2005 ---GDMDVSVPKVEGEMKVPDVDIKGPKM--DIDAPDVDVHGPDWHLKMPKMKMPKF--S 2057
                D+ +S+  +E +++ P   + G ++  D+   D +V   D   KMPK KMP F  S
Sbjct: 787  VTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKEVTAKDSKFKMPKFKMPSFGVS 846

Query: 2058 MPGFKAEGPEVDVNLPK--ADVVVSGPKVDVEVPDVSLEGPEGKLK-------------- 2101
             PG K+    VDV+ PK  ADV +S  + D++  D+S++ P   L+              
Sbjct: 847  APG-KSMEDSVDVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGP 905

Query: 2102 -----GPKLKMPEMH---FKAPKISM--PDVD-----LHLKGPKVK---GDVDVSLPKLE 2143
                 GPK+ +P++    FK PK+ +  P +D     L LKGPK +    D +VSLP +E
Sbjct: 906  VPEGAGPKVHLPKVEMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDGEVSLPSME 965

Query: 2144 GDLTGPSV---------DVEVPDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVNLNLK 2194
             D+              D+ + D ++   D+K K PKFKMP      P  S+  + +++ 
Sbjct: 966  VDVQAQKAKLDGAWLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIKAL-VDVS 1024

Query: 2195 GPKVKGDMDVSVPKVEGEMKVPDVDIRGPKVD--IDAPDVDVHGPDWHLK--------MP 2244
             PKV+ D+  S+P ++G++K  D+ I+    D  + A  VDV  P+ HL         +P
Sbjct: 1025 APKVEADL--SLPSMQGDLKTTDLSIQPASTDLKVQADQVDVKLPEGHLPEGAGLKGHLP 1082

Query: 2245 KMKMPKFSMPGFKGEGPEVDVNLPKADV-----DVSGPKVDVEVP--DVSLEGPEGKLKG 2297
            K++MP F MP    +GP+VDV  PK D+     +V+ P V+V +P  +V +E P  KL  
Sbjct: 1083 KVEMPSFKMPKVALKGPQVDVKGPKLDLKSPKAEVTAPDVEVSLPSVEVDVEAPGAKLDS 1142

Query: 2298 PKFK-----------MPEMHFKTPKISMPDVDFNLKGPKIKGDVDVSAPKLE-------- 2338
             + +             +  FK PK  MP    +  G  I+  VDVSAPK+E        
Sbjct: 1143 ARLEGELSLADKDVTAKDSRFKMPKFKMPSFGASAPGKSIEASVDVSAPKVEADVSLPSM 1202

Query: 2339 -GELKGPELDVKGPKLDADM--------------PEVA-VEGPNGKWKTPKFKMPDMHFK 2382
             G+LK  +L ++ P  D ++              PE A  +G   K + P  KMP +  K
Sbjct: 1203 QGDLKTTDLSIQPPSADLEVHAGQVDVKLLEGHVPEGAGFKGHLPKVQMPSLKMPKVDLK 1262

Query: 2383 APKISMPDLDLHLKSPKAK---GEVDVDVPKLEGDLKGPHV---------DVSGPDIDIE 2430
             P++ +    L LK  KA+    EV V +P +E D++ P           D+S  D D+ 
Sbjct: 1263 GPQVEVRGPKLDLKGHKAEVTAHEVAVSLPSVEVDMQAPGAKLDGAQLDGDLSLADKDVT 1322

Query: 2431 GPEGKLKGPKFKMPDMHFKAPNISMPDVDLNLKGPKIKGDVDVSVPEVEGKLEVPDMNIR 2490
              + K K PKFKMP     AP  S+ +  ++L  PK+  + D+S+P ++G L+  D++I+
Sbjct: 1323 AKDSKFKMPKFKMPSFGVSAPGKSI-EASVDLSAPKV--EADMSLPSMQGDLKTTDLSIQ 1379

Query: 2491 GPKVDVNAP----DVQAPDWHLK--------MPKMKMPKFSMPGFKAEGPEVDVNLPKAD 2538
             P  D+       DV+ P+  +         +PK++MP F +P    +GPE+D+  PK  
Sbjct: 1380 PPSTDLELQAGQLDVKLPEGPVPEGAGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPK-- 1437

Query: 2539 VDISGPKVDIEGPDV---------NIEGPEGKLKGPKLK-----------MPEMNIKAPK 2578
            +D+  PKV++  PDV         ++E P  KL G +L+             +   K PK
Sbjct: 1438 LDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGGRLEEDMSLADKDLTTKDSKFKMPK 1497

Query: 2579 ISMPDFDLHLKGPKVKGDVDVSLPKVE---------GDLKGPEVDIKGPKVD--INAPDV 2627
              MP F +   G  ++  VDVS PKVE         GDLK  ++ I+ P  D  + A  V
Sbjct: 1498 FKMPSFGVSAPGKSIEASVDVSAPKVEADVSLPSMQGDLKATDLSIQPPSADLEVQAGQV 1557

Query: 2628 GVQGPDWHLK--------MPKVKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPKVDIEGP 2679
             V+ P+  +         +PKV+MP F MP    +GP  DVK PK  +D+ GPKV++  P
Sbjct: 1558 DVKLPEGPVSEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPK--LDLKGPKVEVTAP 1615

Query: 2680 DV---------NIEGPEGKLKG-----------------------PKFKMPEMNIKAPKI 2707
            DV         +++ P  KL G                       PKFKMP   + AP  
Sbjct: 1616 DVKMSLSSMEVDVQAPRAKLDGAQLEGDLSLADKAVTAKDSKFKMPKFKMPSFGVSAPGK 1675

Query: 2708 SMPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDID--APDVDVHGPDWHLK 2765
            S+ +  +++  PKV  + DVSLP ++GDLK  ++ I+ P  D++  A  V+V  P+  L 
Sbjct: 1676 SI-EASVDVSEPKV--EADVSLPSMQGDLKTTDLSIQSPSADLEVQAGQVNVKLPEGPLP 1732

Query: 2766 --------MPKIKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDV-------- 2809
                    +PK++MP + MP    +GP +DV  PK  +D+ GPK +V  PDV        
Sbjct: 1733 EGAGFKGHLPKVQMPSLKMPKVALKGPQMDVKGPK--LDLKGPKAEVMAPDVEVSLPSVE 1790

Query: 2810 -NIEGPEGKWKSPKFK-----------MPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTG 2857
             ++E P  K  S + +             +  FK PK  MP   ++  G  I+  VDV+ 
Sbjct: 1791 VDVEAPGAKLDSVRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSA 1850

Query: 2858 PKVE---------GDLKG-------PEVDL--KGPKVDIDVPDVNV-QGPDWHLKMPKMK 2898
            PKVE         GDLK        P  DL  +  +VD+ +P+  V +G      +PK+ 
Sbjct: 1851 PKVEAEVSLPSMQGDLKTTDLCIPLPSADLVVQAGQVDMKLPEGQVPEGAGLKGHLPKVD 1910

Query: 2899 MPKFSMPGFKAEGPEVDVNLPKADVDVSGPKVDVEGPDVNIEGP---------------- 2942
            MP F MP    +GP+ DV    A +D+ GPK +V  PDV +  P                
Sbjct: 1911 MPSFKMPKVDLKGPQTDVK--GAKLDLKGPKAEVTAPDVEVSLPSMEVDVQAQKAKLDGA 1968

Query: 2943 ----------------EGKLKGPKFKMPEMNIKAPKIPMPDFDLHLKGPKVKGDVDISLP 2986
                            + K K PKFKMP   + AP   + +  + +  PKV+ DV  SLP
Sbjct: 1969 RLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGRSI-EASVDVPAPKVEADV--SLP 2025

Query: 2987 KVEGDLKGPEVDIRGPQVDIDVP--DVGVQGPDWHLK--------MPKVKMPKFSMPGFK 3036
             ++GDLK  ++ I+ P  D+ V    V V+ P+ H+         +PKV+MP   MP   
Sbjct: 2026 SMQGDLKTTDLSIQPPSADLKVQTGQVDVKLPEGHVPEGAGLKGHLPKVEMPSLKMPKVD 2085

Query: 3037 GEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGP-------------------------- 3070
             +GP VD+  PK  LD+  PKV++ VPDV +  P                          
Sbjct: 2086 LKGPQVDIKGPK--LDLKDPKVEMRVPDVEVSLPSMEVDVQAPRAKLDSAHLQGDLTLAN 2143

Query: 3071 ------EGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMKVPD 3124
                  + K K PKFKMP   + AP  S+ +  +++  PKV+ DM  SLP ++GD+K  D
Sbjct: 2144 KDLTTKDSKFKMPKFKMPSFGVSAPGKSI-EASVDVSPPKVEADM--SLPSMQGDLKTTD 2200

Query: 3125 VDIKGPKVDIN--APDVDV---QGP---DWHLK--MPKIKMPKISMPGFKGEGPEVDVNL 3174
            + I+    D+   A  VDV   +GP   +  LK  +PK++MP   +P    +GPE+D+  
Sbjct: 2201 LSIQPLSADVKVQAGQVDVKLLEGPVPEEVGLKGHLPKLQMPSFKVPKVDLKGPEIDIKG 2260

Query: 3175 PKADL-----DVSGPKVDVDVP--DVNIEGPDAKLKGP------------------KFKM 3209
            PK DL     +V+ P V+V +P  +V+++ P AKL G                   KFKM
Sbjct: 2261 PKLDLKDPKVEVTAPDVEVSLPSVEVDVKAPGAKLDGARLEGDMSLADKDVTAKDSKFKM 2320

Query: 3210 PEMNIKAPKISM--PDLDLNLKGPKMKGEVDVSLANVEGDLKGPALDIKGPKID--VDAP 3265
            P+  + +  +S     ++ +     +K E DVSL +++GDLK   L ++ P  D  V A 
Sbjct: 2321 PKFKMLSFGVSALGKSIEASADVSALKVEADVSLPSMQGDLKTTDLSVQPPSADLEVQAG 2380

Query: 3266 DIDIHGPD------AKLKG--PKLKMPDMHVNMPKISMPEIDLNLKGSKLKGDVDVSGPK 3317
             +D+  P+      A LKG  PKL+MP     MPK+ +    +++KG KL    D+ GPK
Sbjct: 2381 QVDVKLPEGPVPEGAGLKGHLPKLQMPSF--KMPKVDLKGPQIDVKGPKL----DLKGPK 2434

Query: 3318 LEGDIKAPSLDIKGP--EVDVSGPKLNIEGK--------------SKKSRFKLPKFNFSG 3361
               D+ AP +++  P  EVDV  P   ++G               +K SRFK+PKF    
Sbjct: 2435 T--DVMAPDVEVSQPSVEVDVEAPGAKLDGAWLEGDLSVADKDVTTKDSRFKIPKFKMPS 2492

Query: 3362 SKVQTPEVDVKGKKPDIDITGPKVDINAPDVEVQGKVKGSKF------------------ 3403
              V  P   ++     +D++ PKV+ +     +QG +K +                    
Sbjct: 2493 FGVSAPGKSIEAS---VDVSAPKVEADGSLSSMQGDLKATDLSIQPPSADLEVQAGQVDV 2549

Query: 3404 KMPFLSISS--------PKVSMPDV---ELNLKSPKVKGDLDIAGPNLEGDFKGPKVDIK 3452
            K+P   +          PKV MP     E++LK P+    LD+ GP L  D KGPK ++ 
Sbjct: 2550 KLPEGPVPEGAGLKGHLPKVQMPSFKMPEMDLKGPQ----LDVKGPKL--DLKGPKAEVT 2603

Query: 3453 APEV--NLNAPDVDVHGP-----------------------DWNLKMPKMKMPKFSVSG- 3486
            AP+V  +L++ +VDV  P                       D   KMPK KMP F VS  
Sbjct: 2604 APDVEMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGVTAKDSKFKMPKFKMPSFRVSAP 2663

Query: 3487 ------------LKAEG----PDVAVDLPKGDINIEGPS--MNIEGPDLNVEGPEG---- 3524
                        LK E     P +  DL   DI+I+ PS  + ++   ++V+ PEG    
Sbjct: 2664 GESIEALVDVSELKVEADMSLPSMQGDLKTTDISIQPPSAQLEVQAGQVDVKLPEGHVPE 2723

Query: 3525 --GLKG-------PKFKMPDMNIKAPKISMPDIDLNLKGPKVK---GDVDISLPKLEGDL 3572
              GLKG       P FKMP++++K P+I +   +++LKGPK +    DV +SL  +E D+
Sbjct: 2724 GAGLKGHLPKLQMPSFKMPEVDLKGPQIDVKGPNVDLKGPKAEVTAPDVKMSLSSMEVDV 2783

Query: 3573 KGPEVDIKGPKV--DINAPDVDVHGPDWHLKMPKVKMPKF-------------------- 3610
            + P   + G ++  D++  D  +   D   KMPK KMP F                    
Sbjct: 2784 QAPRAKLDGARLEGDLSLADKGMTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSELKV 2843

Query: 3611 ----SMPGFKGEGPEVDVTL--PKADIDISGPNVDVDVPD------VNIEGPDAKLKGPK 3658
                S P  +G+    D+ +  P A +++    VDV +P+        ++G   K++ P 
Sbjct: 2844 EADGSFPSMQGDLKTTDIRIQPPSAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVQMPS 2903

Query: 3659 FKMPEMNIKAPKISMPDFDLNLKGPKMK---GDVVVSLPKVEGDLKGPEVDIKGPKV--D 3713
            FKMP++++K P+I +    L+LKGPK +    DV VSLP VE D++ P   + G ++  D
Sbjct: 2904 FKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDVEVSLPSVEVDVEAPRAKLDGARLEGD 2963

Query: 3714 IDTPDINIEGSEGKFKGPKFKIPEMHLKAPKISMPDIDLNLKGPKVKGDVDVSLPKMEGD 3773
            +   D ++   + KFK PKFK+P   + AP  S+ ++ +++  PKV  + +VSLP M+GD
Sbjct: 2964 LSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSI-EVSVDVSAPKV--EAEVSLPSMQGD 3020

Query: 3774 LKGPEVDIKGP--KVDINAPDVDVQGPDWHLK--------MPKVKMPKFSMPGFKGEGPD 3823
            LK  ++ I+ P  ++++ A  VD++ P+ H+         +PK++MP F MP    +GP 
Sbjct: 3021 LKTTDISIEPPSAQLEVQAGQVDLKLPEGHVPEGAGLKGHLPKLQMPSFKMPKVDRKGPQ 3080

Query: 3824 VDVNLPKADLDVSGPKVDIDVPDVNIEGP------------------------------- 3852
            +DV  PK  LD+ GPK D+  PDV +  P                               
Sbjct: 3081 IDVKGPK--LDLKGPKTDVTAPDVEVSQPGMEVDVEAPGAKLDGARLEGDLSLADKDVTA 3138

Query: 3853 -EGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMQVPDLDIKG 3911
             + K K PKFKMP   + AP  S+ ++ +++  PKV+ D+  SLP ++GD++  D+ I+ 
Sbjct: 3139 KDSKFKMPKFKMPSFGVSAPGKSI-EVLVDVSAPKVEADL--SLPSMQGDLKNTDISIEP 3195

Query: 3912 P--KVDINAPDVDVRGPDWHL--------KMPKIKMPKISMPGFKGEGPEVDVNLPKADL 3961
            P  ++++ A  VDV+ P+ H+         +PK++MP   MP    +GP++D+  PK  L
Sbjct: 3196 PSAQLEVQAGQVDVKLPEGHVLEGAGLKGHLPKLQMPSFKMPKVDRKGPQIDIKGPK--L 3253

Query: 3962 DVSGPKVDVDVPDV---------NIEGPDAKLKGPKFK-----------MPEMNIKAPKI 4001
            D+ GPK+DV  PDV         ++E P AKL G + +             +   K PK 
Sbjct: 3254 DLKGPKMDVTAPDVEVSQPSMEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKMPKF 3313

Query: 4002 SMPDFDLHLKGPKV---------KGDVDVSLPKMEGDLKAPEVDIKGPKVDID--APDVD 4050
             MP +     G  +         K + DVSLP M+GDLK  ++ I+ P VD++  A  VD
Sbjct: 3314 KMPSYRASAPGKSIQASVDVSAPKAEADVSLPSMQGDLKTTDLSIQLPSVDLEVQAGQVD 3373

Query: 4051 VHGPDWHLK--------MPKVKMPKFSMPGFKGEGPEVDVNLPKADIDVSGPKVDIDTPD 4102
            V  P+ H+         +PKV+MP F MP    + P+VD+  PK D+ V  PK ++  PD
Sbjct: 3374 VKLPEGHVPEGAGLKGHLPKVEMPSFKMPKVDLKSPQVDIKGPKLDLKV--PKAEVTVPD 3431

Query: 4103 I---------DIHGPEGKLKG-----------------------PKFKMPDLHLKAPKIS 4130
            +         D+  P  KL G                       PKFKMP   + AP  S
Sbjct: 3432 VEVSLPSVEVDVQAPRAKLDGARLEGDLSLAEKDVTAKDSKFKMPKFKMPSFGVSAPGRS 3491

Query: 4131 MPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDVPDVDV----------Q 4180
            + E  L++  PK+  + DVSL  ++GDLK  ++ I+ P  D++V  V V          +
Sbjct: 3492 I-EASLDVSAPKV--EADVSLSSMQGDLKATDLSIQPPSADLEVQAVQVDVELLEGPVPE 3548

Query: 4181 GPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGP---- 4236
            G      +PKV+MP    P    +GP +DV  PK  LD+ GPK ++ VPDV +  P    
Sbjct: 3549 GAGLKGHLPKVEMPSLKTPKVDLKGPQIDVKGPK--LDLKGPKAEVRVPDVEVSLPSVEV 3606

Query: 4237 ----------------------------DAKLKGPKFKMPEMNIKAPKISMPDFDLHLKG 4268
                                        D+K K PKFKMP   + AP  SM +  + +  
Sbjct: 3607 DVQAPKAKLDAGRLEGDLSLADKDVTAKDSKFKMPKFKMPSFRVSAPGKSM-EASVDVSA 3665

Query: 4269 PKVKGDVDVSLPKVEGDLKGPEVDIKGPKVD--IDAPDVDVHGPDWHLK--------MPK 4318
            PKV  + DVSLP ++GDLK  ++ I+ P  D  + A  +DV  P+  +         +PK
Sbjct: 3666 PKV--EADVSLPSMQGDLKTTDLSIQPPSADLKVQAGQMDVKLPEGQVPEGAGLKEHLPK 3723

Query: 4319 VKMPKFSMPGFKGEGPDVDVTLPKADI-----EISGPKVDIDAP--DVSIEGP------- 4364
            V+MP   MP    +GP VD+  PK D+     E++ P V++  P  +V ++ P       
Sbjct: 3724 VEMPSLKMPKVDLKGPQVDIKGPKLDLKVSKAEVTAPDVEVSLPSVEVDVQAPRAKLDSA 3783

Query: 4365 ----------------DAKLKGPKFKMPEMNIKAPKISMPDIDFNLKGPKVKGDVDVSLP 4408
                            D+K K PKFKMP   + AP  S+ +   ++  PKV  + DVSLP
Sbjct: 3784 QLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSI-EASVHVSAPKV--EADVSLP 3840

Query: 4409 KVEGDLKGPEIDIKGPSLDIDTP---------------DVNIEGPEGKLKGPKFKMPEMN 4453
             ++GDLK  ++ I+  S D+                  +  ++G   K++ P FKMP+++
Sbjct: 3841 SMQGDLKTTDLSIQPHSADLTVQARQVDMKLLEGHVPEEAGLKGHLPKVQMPSFKMPKVD 3900

Query: 4454 IKAPKISMPDFDLHLKGPKVK---GDVDVSLPKVESDLKGPEVDIEGP------------ 4498
            +K P+I +    L LK PKV+    DV+VSLP VE D++ P   ++G             
Sbjct: 3901 LKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGARLEGDLSLADKD 3960

Query: 4499 ----EGKLKGPKFKMPDVHFKSPQISMSDIDLNLKGPKIKGDMDISVPKLEGDLKGPKVD 4554
                + K K PKFKMP     +P  SM +  +++  PK++ D  +S+P ++GDLK   + 
Sbjct: 3961 MTAKDSKFKMPKFKMPSFGVSAPGKSM-EASVDVTAPKVEAD--VSLPSMQGDLKATDLS 4017

Query: 4555 VKGPKVGIDTP--DIDIHGPEG-------------KLKGPKFKMPDLHLKAPKISMPEVD 4599
            V+ P   ++     +D+  PEG             K++ P FKMP + LK P+I +    
Sbjct: 4018 VQPPSADLEVQAGQVDVKLPEGPVPEGASLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPK 4077

Query: 4600 LNLKGPKVKGDMDISLPKVEGDLKGPEVDIRDPKV---------DIDVPDVDVQGPDWHL 4650
            L+LKGPK     +++ P V+  L   EVD++ P+          D+ + D DV   D   
Sbjct: 4078 LDLKGPKA----EVTAPDVKMSLSSMEVDVQAPRAKLDGVQLEGDLSLADKDVTAKDSKF 4133

Query: 4651 KMPKVKMPKF------------------------SMPGFKGE--GPDVDVNLPKADIDVS 4684
            KMPK KMP F                        S+P  +G+    D+ +  P AD++V 
Sbjct: 4134 KMPKFKMPSFGVSAPGKSMEASVDVSELKAKADVSLPSMQGDLKTTDLSIQSPSADLEVQ 4193

Query: 4685 GPKVDVDVPD------VNIEGPDAKLKGPKFKMPEMSIKAPKISMPDIDLNLKGPK---V 4735
              +VDV +P+        ++G   K++ P  KMP++++K P++ +    L+LKGPK   +
Sbjct: 4194 AGQVDVKLPEGPLPKGAGLKGHLPKVQMPCLKMPKVALKGPQVDVKGPKLDLKGPKADVM 4253

Query: 4736 KGDVDVTLPKVEGDLKGPEADIKGPKV--DINTPDVDVHGPDWHLKMPKVKMPKF----- 4788
               V+V+LP +E D++ P A +   ++  D++  D D+   D   KMPK KMP F     
Sbjct: 4254 TPVVEVSLPSMEVDVEAPGAKLDSVRLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAP 4313

Query: 4789 -------------------SMPGFKGEGPDVDVSL--PKADIDVSGPKVDVDIPD----- 4822
                               S+P  +G+     +S+  P AD++V   + DV +P+     
Sbjct: 4314 GKSIEASLDVSALKVEADVSLPSMQGDLKTTHLSIQPPSADLEVQAGQEDVKLPEGPVHE 4373

Query: 4823 -VNIEGPDAKLKGPKFKMPEINIKAPKISIPDVDLDLKGPKVK---GDFDVSVPKVEGTL 4878
               ++G   KL+ P FK+P++++K P+I +    LDLKGPKV+    + DVS+P +E  +
Sbjct: 4374 GAGLKGHLPKLQMPSFKVPKVDLKGPQIDVNVPKLDLKGPKVEVTSPNLDVSLPSMEVDI 4433

Query: 4879 KGPEVDLKGPRL---------DFEGPDAKLSGPSLKMPS-------------LEISAPKV 4916
            + P   L   RL         D    D+K   P  KMPS             +++SAPK+
Sbjct: 4434 QAPGAKLDSTRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGMLSPGKSIEVSVDVSAPKM 4493

Query: 4917 TA----PDVDLHLKAPKIGFSGP----KLEGGEVDLKGPKVEAPSL--------DVHMDS 4960
             A    P +   LK   +    P    +++ G+VDLK P+   P +         V M S
Sbjct: 4494 EADMSIPSMQGDLKTTDLRIQAPSADLEVQAGQVDLKLPEGHMPEVAGLKGHLPKVEMPS 4553

Query: 4961 ---PDINIEGPDVKIPKFKKPKFGFGAKSPKADIKSPSLDVTVPEAELNLETPEISVGGK 5017
               P ++++GP V +   K PK     K PKA++ +P ++V++P  E +++ P   + G 
Sbjct: 4554 FKMPKVDLKGPQVDV---KGPKLDL--KGPKAEVMAPDVEVSLPSVETDVQAPGSMLDGA 4608

Query: 5018 --------------GKKSKFKMPKIHMSGPKIKAKKQGFDLNVPGGEI------------ 5051
                          GK SKF+ PK+  SG +  +KK     +   G +            
Sbjct: 4609 RLEGDLSLAHEDVAGKDSKFQGPKLSTSGFEWSSKKVSMSSSEIEGNVTFHEKTSTFPIV 4668

Query: 5052 -----DASLKAPDVDVNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEFDIKSPKFKAEA 5106
                 +  L  P  D N+      + +D K        F K++F   +    S K   ++
Sbjct: 4669 ESVVHEGDLHDPSRDGNLGLAVGEVGMDSK--------FKKLHFKVPKVSFSSTKTPKDS 4720

Query: 5107 PLPSPKLEGELQAPDLELSLPAIHVEGLDIKAKAPKVKMPDVDIS-VPKIEGDLKGPKVQ 5165
             +P  K    L    L  S  +            P ++MP V  +  P    DL GP  +
Sbjct: 4721 LVPGAKSSIGLSTIPLSSSECSSFELQQVSACSEPSMQMPKVGFAGFPSSRLDLTGPHFE 4780

Query: 5166 ANLGAPDINIEGLDAKVKTPSFGI---------SAPQVSIP----DVNVNLKGPKIKGDV 5212
            +++ +P  ++     +V  P   +         S  Q  IP    + + +L+ P+    V
Sbjct: 4781 SSILSPCEDVTLTKYQVTVPRAALAPELALEIPSGSQADIPLPKTECSTDLQPPE---GV 4837

Query: 5213 PSVGLEGPDVDLQG----PEAKIKFPKFSMPK------------------IGIPGVKMEG 5250
            P+   E     L         ++ FPKF  PK                  +G P +    
Sbjct: 4838 PTSQAESHSGPLNSMIPVSLGQVSFPKFYKPKFVFSVPQMAVPEGDLHAAVGAPVMSPLS 4897

Query: 5251 GGAEVHAQLPSLE--------------------------GDLRGPDVKLEGPDVSLKGPG 5284
             G  V   LPS +                          G+    D   EG    LK P 
Sbjct: 4898 PGERVQCPLPSTQLPSPGTCVSQGPEELVASLQTSVVAPGEAPSEDADHEGKGSPLKMPK 4957

Query: 5285 VDLPSVNLSMPKVSGPDLD----LNLKGPSLKGDLDASVPSMKVH--------------- 5325
            + LPS   S  K +GP +D    +     SL  D D   P   +H               
Sbjct: 4958 IKLPSFRWSPKKETGPKVDPECSVEDSKLSLVLDKDEVAPQSAIHMDLPPERDGEKGRST 5017

Query: 5326 APGLNLSGVG-GKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPK 5384
             PG  +  +   KM+    GV +P  D    L+         G S Q     S D    +
Sbjct: 5018 KPGFAMPKLALPKMKASKSGVSLPQRDVDPSLSSAT-----AGGSFQDTEKASSD--GGR 5070

Query: 5385 VSVGAPDLSLEASEG-SIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLK 5443
              +GA   S   SEG ++  P++ +P  G + P      + +  +   E+  P  D+ L 
Sbjct: 5071 GGLGA-TASATGSEGVNLHRPQVHIPSLGFAKP------DLRSSKAKVEVSQPEADLPL- 5122

Query: 5444 GPRISAPNVDFNLEGPKVKGSLG------ATGEIKGPTVGGGL------PGIGVQGLEG- 5490
                  P  D + EG      LG        GE   PT    L      P   V  +E  
Sbjct: 5123 ------PKHDLSTEGDSRGCGLGDVPVSQPCGEGIAPTPEDPLQPSCRKPDAEVLTVESP 5176

Query: 5491 -----------------NLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVG 5533
                               +MP ++ S  D    G   KL   Q   P   GG       
Sbjct: 5177 EEEAMTKYSQESWFKMPKFRMPSLRRSFRDRGGAG---KLEVAQTQAPAATGG------- 5226

Query: 5534 FHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDI------SLG-EG 5586
                  + + K   F ++    +  ++L+ P+       S   S+ DI      S G + 
Sbjct: 5227 ------EAAAKVKEFLVSGSNVEAAMSLQLPEADAEVTASESKSSTDILRCDLDSTGLKL 5280

Query: 5587 HLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKV---EGGVKGGQIG---LQAPGL 5640
            HLS  G  G+      +S + +  SK  G L F  P +   E  V  G+I    L  PG 
Sbjct: 5281 HLSTAGMTGD---ELSTSEVRIHPSK--GPLPFQMPGMRLPETQVLPGEIDETPLSKPGH 5335

Query: 5641 SVSGPQGHLESGSGKVTFPKMKIPKFTFSGRELVGREMGVDVHFPKAEASIQAGAGDGEW 5700
             ++  +   E  S +   P     K   S  ++  +   V+V              D  W
Sbjct: 5336 DLASMEDKTEKWSSQPEGPL----KLKASSTDMPSQISVVNV--------------DQLW 5377

Query: 5701 EESEVKLKKSKIKMPKFNFSKPKGKGGV 5728
            E+S + +K  K+ +P+F+F  P  +  V
Sbjct: 5378 EDSVLTVKFPKLMVPRFSFPAPSSEDDV 5405



 Score = 1581 bits (4093), Expect = 0.0
 Identities = 1542/5755 (26%), Positives = 2496/5755 (43%), Gaps = 1429/5755 (24%)

Query: 2    EKEETTRELLLPNWQGSGSHGLTIAQR-DDGVFVQEVTQNSPAARTGVVKEGDQIVGATI 60
            E  +   E+ L     +G+ G ++    D G+FV++V ++S AA+   ++EGDQ++  T+
Sbjct: 105  EAVQEATEVTLKTEVEAGASGYSVTGGGDQGIFVKQVLKDSSAAKLFNLREGDQLLSTTV 164

Query: 61   YFDNLQSGEVTQLLNTMGHHTVGLKLHRKGDRSPEPGQTWTREVFSSCSSEVVLSGDDEE 120
            +F+N++  +  ++L     + V  K+ R+    P P      E ++S  ++    G ++E
Sbjct: 165  FFENIKYEDALKILQYSEPYKVQFKIRRQ---LPAPQD----EEWASSDAQHGPQGKEKE 217

Query: 121  YQRIYTTKIKPRLKSEDGVEGDLGETQSRTITVTRRVTAYTVDVTGREGAKDIDISSPEF 180
               +     +   K+ +G +GD    Q R I+  R          GR+  ++  +S P+F
Sbjct: 218  DTDVADGCRETPTKTLEG-DGD----QERLISKPRVGR-------GRQSQRE-RLSWPKF 264

Query: 181  KIKIPRHELTEISNVDVETQSGKTVIRLPSGSGAASPTGSAVDIRAGAISASGPELQGAG 240
            +               ++++ G    R  S S A  P     D    + +++  E Q   
Sbjct: 265  Q--------------SIKSKRGPGPQRSHSSSEAYEPR----DAHDVSPTSTDTEAQLTV 306

Query: 241  HSKLQVTMPGIKVGGSGVNVNAKGLDLGGRGGVQVPAVDISSSLGGRAV-EVQGPSLESG 299
              + Q   PG +     +N+  +     G      P     S +G   V E  GP  +S 
Sbjct: 307  ERQEQKAGPGSQRRRKFLNLRFRTGSGQGPSSTGQPGRGFQSGVGRAGVLEELGPWGDS- 365

Query: 300  DHGKIKFPTMKVPKFGVSTG--REGQTPKAGLRVSAPEVSVGHKGGKPGLTIQAPQLEVS 357
                       + + G +TG  RE +  +    + A  + +  + G P L    PQ    
Sbjct: 366  -----------LEETGAATGSRREERAEQDREVMPAQSMPLPTELGDPRLCEGTPQ---- 410

Query: 358  VPSANIEGLEGKLKGPQITGPSLEG---DLGLKGAKPQGHIGVDASAPQIGGSITGPSVE 414
                     EG L+  ++ G +LEG   +  +   KP+         P  G S  G    
Sbjct: 411  ---------EGGLRAARLHGKTLEGQAQETAVAQRKPRAQ-------PTPGMSREGEGEG 454

Query: 415  VQAPDIDVQG---------------PGSKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGE 459
            +Q+ +I +                 P  ++ V  +K PKF+ S  K  E    ++ P   
Sbjct: 455  LQSLEIGIARLSLRDTTEGGTQIGPPEIRVRVHDLKTPKFAFSTEKEPERERRLSTPQR- 513

Query: 460  VTVPGVSGDVSLPEIATGGLEGKMKGTKVKTPEMIIQKPKISMQDVDLSLGSPKLKGDIK 519
                G   D S  +  TG     +KG +V+                    G+  + G   
Sbjct: 514  ----GKRQDAS-SKAGTG-----LKGEEVE--------------------GAGWMPGREP 543

Query: 520  VSAPGVQGDVKGPQVALKGSRVDIETP----NLEGTLTGPRLGSPS-------------- 561
             +    QGD    +  L+ +R+  E      + EG +  P+   PS              
Sbjct: 544  TTHAEAQGDEGDGEEGLQRTRITEEQDKGREDTEGQIRMPKFKIPSLGWSPSKHTKTGRE 603

Query: 562  --------GKTGTCRISMSEVDLNVAAPKVKGGVDVTLPRVEGKVKVPEVDVRGPKVDVS 613
                    G+ G    +    +       +K   D        K+++   + R  K  + 
Sbjct: 604  KATEDTEQGREGEATATADRREQRRTEEGLKDKEDSDSMTNTTKIQLIHDEKRLKKEQIL 663

Query: 614  APDVEAHGPEWNLKMPKMKMPTFSTPGAKGEGPDVHMTLPKGDISISGPKVNVEAPDVNL 673
              + E    +   KMPK KMP F   GA   G  +     +  + +S PKV  +   +++
Sbjct: 664  T-EKEVATKDSKFKMPKFKMPLF---GASAPGKSM-----EASVDVSAPKVEADVSLLSM 714

Query: 674  EGLGGKLKGPDVKLPDMSVKTPKISMPDVDLHVKGTKVKGEYDVTVPKLEGELKGPKVDI 733
            +G        D+K  D+SV+TP       DL V+     G+ DV +P  EG L       
Sbjct: 715  QG--------DLKTTDLSVQTPS-----ADLEVQD----GQVDVKLP--EGPLP------ 749

Query: 734  DAPDVDVHGPDWHLKMPKMKMPKFSVPGFKAEGPEVDVNLPKADVDISGPKIDVTAPDVS 793
                    G      +PK++ P   +P    +GP++D+  PKA+V     K+ +++ +V 
Sbjct: 750  -------EGASLKGHLPKVQRPSLKMPKVDLKGPKLDLKGPKAEVTAPDVKMSLSSMEVD 802

Query: 794  IEEPEGKLKGPKFK-----------MPEMNIKVPKISMPDVDLHLKGPNVKGEYDVTMPK 842
            ++ P  KL G + +             +   K+PK  MP   +   G +++   DV+ PK
Sbjct: 803  VQAPRAKLDGARLEGDLSLADKEVTAKDSKFKMPKFKMPSFGVSAPGKSMEDSVDVSAPK 862

Query: 843  VESEIKV------------------PDVELKSAKMDIDVPD---VEVQGPDWHLKMPKMK 881
            VE+++ +                   D+E+++ ++D+ +P+    E  GP  HL  PK++
Sbjct: 863  VEADVSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGPKVHL--PKVE 920

Query: 882  MPKFSMPGFKAEGPEVDVNLPKADVDISGPKVGVEVPD---------VNIEGPEGKLKG- 931
            MP F MP    +GP++DV  PK  +D+ GPK  V  PD         V+++  + KL G 
Sbjct: 921  MPSFKMPKVDLKGPQIDVKGPK--LDLKGPKAEVTAPDGEVSLPSMEVDVQAQKAKLDGA 978

Query: 932  ----------------------PKFKMPEMNIKAPKISMPDVDLHMKGPKVKGEYDMTVP 969
                                  PKFKMP   + AP  S+  + + +  PKV  E D+++P
Sbjct: 979  WLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIKAL-VDVSAPKV--EADLSLP 1035

Query: 970  KLEGDLK----------------GPKVDVSAPDVEM-QGPDWNLKMPKIKMPKFSMPSLK 1012
             ++GDLK                  +VDV  P+  + +G      +PK++MP F MP + 
Sbjct: 1036 SMQGDLKTTDLSIQPASTDLKVQADQVDVKLPEGHLPEGAGLKGHLPKVEMPSFKMPKVA 1095

Query: 1013 GEGPEFDVNLSKANVDISAPKVDTNAPD---------LSLEGPEGKLKGPKFK------- 1056
             +GP+ DV   K  +D+ +PK +  APD         + +E P  KL   + +       
Sbjct: 1096 LKGPQVDVKGPK--LDLKSPKAEVTAPDVEVSLPSVEVDVEAPGAKLDSARLEGELSLAD 1153

Query: 1057 ----MPEMHFRAPKMSLPDVDLDLKGPKMKGNVDISAPKIEGEMQVP------------- 1099
                  +  F+ PK  +P       G  ++ +VD+SAPK+E ++ +P             
Sbjct: 1154 KDVTAKDSRFKMPKFKMPSFGASAPGKSIEASVDVSAPKVEADVSLPSMQGDLKTTDLSI 1213

Query: 1100 -----DVDIRGPKVDIKAPDVEG---QGLDWSLKIPKMKMPKFSMPSLKGEGPEVDVNLP 1151
                 D+++   +VD+K   +EG   +G  +   +PK++MP   MP +  +GP+V+V  P
Sbjct: 1214 QPPSADLEVHAGQVDVKL--LEGHVPEGAGFKGHLPKVQMPSLKMPKVDLKGPQVEVRGP 1271

Query: 1152 KAD------------VVVSGP--KVDIEAPDVSLEG----------------PEGKLKGP 1181
            K D            V VS P  +VD++AP   L+G                 + K K P
Sbjct: 1272 KLDLKGHKAEVTAHEVAVSLPSVEVDMQAPGAKLDGAQLDGDLSLADKDVTAKDSKFKMP 1331

Query: 1182 KFKMPEMHFKTPKISMPDVDLHLKGPKVKGDVDVSVPKVEGEMKVPDVEIKGPKMDID-- 1239
            KFKMP      P  S+ +  + L  PKV  + D+S+P ++G++K  D+ I+ P  D++  
Sbjct: 1332 KFKMPSFGVSAPGKSI-EASVDLSAPKV--EADMSLPSMQGDLKTTDLSIQPPSTDLELQ 1388

Query: 1240 APDVEVQGPDWHL--------KMPKMKMPKFSMPGFKGEGREVDVNLPKAD-----IDVS 1286
            A  ++V+ P+  +         +PK++MP F +P    +G E+D+  PK D     ++V+
Sbjct: 1389 AGQLDVKLPEGPVPEGAGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKLDLKDPKVEVT 1448

Query: 1287 GPKVDVEVP--DVSLEGPEGKLKG-----------------------PKFKMPEMHFKAP 1321
             P V+V +P  +V +E P  KL G                       PKFKMP     AP
Sbjct: 1449 APDVEVSLPSVEVDVEAPGAKLDGGRLEEDMSLADKDLTTKDSKFKMPKFKMPSFGVSAP 1508

Query: 1322 KISMPDVDLNLKGPKLKGDVDVSLPEVEGEMKVPDVDIKGPKVD--ISAPDVDVHGPDWH 1379
              S+ +  +++  PK+  + DVSLP ++G++K  D+ I+ P  D  + A  VDV  P+  
Sbjct: 1509 GKSI-EASVDVSAPKV--EADVSLPSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGP 1565

Query: 1380 LK--------MPKVKMPKFSMPGFKGEGPEVDVKLPKADVDVSGPKMDAEVPD------- 1424
            +         +PKV+MP F MP    +GP++DVK PK  +D+ GPK++   PD       
Sbjct: 1566 VSEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPK--LDLKGPKVEVTAPDVKMSLSS 1623

Query: 1425 --VNIEGPDAKLKG-----------------------PKFKMPEMSIKPQKISIPDVGLH 1459
              V+++ P AKL G                       PKFKMP   +     SI +  + 
Sbjct: 1624 MEVDVQAPRAKLDGAQLEGDLSLADKAVTAKDSKFKMPKFKMPSFGVSAPGKSI-EASVD 1682

Query: 1460 LKGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKVD--INAPDVEVHGPDWHL--------K 1509
            +  PK++   DV++P ++G++K  D+ I+ P  D  + A  V V  P+  L         
Sbjct: 1683 VSEPKVEA--DVSLPSMQGDLKTTDLSIQSPSADLEVQAGQVNVKLPEGPLPEGAGFKGH 1740

Query: 1510 MPKVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPD---------VNLEAPEG 1560
            +PKV+MP   MP    +GP++D+  PK DL   GPK ++  PD         V++EAP  
Sbjct: 1741 LPKVQMPSLKMPKVALKGPQMDVKGPKLDL--KGPKAEVMAPDVEVSLPSVEVDVEAPGA 1798

Query: 1561 KL------------------KGPKFKMPSMNIQTHKISMP----DVGLNLKAPKLKTDVD 1598
            KL                  K  KFKMP   + +  +S P    +  +++ APK+  + +
Sbjct: 1799 KLDSVRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSAPKV--EAE 1856

Query: 1599 VSLPKVEGDLKGPEIDVKAPKMD--VNVGDIDIEGPEGK------LKG-------PKFKM 1643
            VSLP ++GDLK  ++ +  P  D  V  G +D++ PEG+      LKG       P FKM
Sbjct: 1857 VSLPSMQGDLKTTDLCIPLPSADLVVQAGQVDMKLPEGQVPEGAGLKGHLPKVDMPSFKM 1916

Query: 1644 PEMHFKAPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKVDIDAP---- 1699
            P++  K P+  +    L LKGPK     +V+ P VE  +   +VD++  K  +D      
Sbjct: 1917 PKVDLKGPQTDVKGAKLDLKGPKA----EVTAPDVEVSLPSMEVDVQAQKAKLDGARLEG 1972

Query: 1700 DVEVHDPDWHLKMPKMKMPKFSMPGFKAEGP------EVDVNLPKADIDVSGPSVDTD-- 1751
            D+ + D D   K  K KMPKF MP F    P       VDV  PK + DVS PS+  D  
Sbjct: 1973 DLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGRSIEASVDVPAPKVEADVSLPSMQGDLK 2032

Query: 1752 ----------------APDLDIEGPEG-------------KLKGSKFKMPKLNIKAPKVS 1782
                               +D++ PEG             K++    KMPK+++K P+V 
Sbjct: 2033 TTDLSIQPPSADLKVQTGQVDVKLPEGHVPEGAGLKGHLPKVEMPSLKMPKVDLKGPQVD 2092

Query: 1783 MPDVDLNLKGPKLK---GEIDASVPELEGDLRGPQVDVKGPFVEAE--VPDVDLECPDAK 1837
            +    L+LK PK++    +++ S+P +E D++ P+  +    ++ +  + + DL   D+K
Sbjct: 2093 IKGPKLDLKDPKVEMRVPDVEVSLPSMEVDVQAPRAKLDSAHLQGDLTLANKDLTTKDSK 2152

Query: 1838 LKGPKFKMPEMHFKAP--------KISMPDVDLHLKGPKVKGD---ADVSVPKLEGDLTG 1886
             K PKFKMP     AP         +S P V+  +  P ++GD    D+S+  L  D+  
Sbjct: 2153 FKMPKFKMPSFGVSAPGKSIEASVDVSPPKVEADMSLPSMQGDLKTTDLSIQPLSADVKV 2212

Query: 1887 PSVGVEVPDVELECPD--------AKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVK- 1937
             +  V+V  +E   P+         KL+ P FK+P +  K P+I +    L LK PKV+ 
Sbjct: 2213 QAGQVDVKLLEGPVPEEVGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKLDLKDPKVEV 2272

Query: 1938 --GDVDVSVPKLEGDLTGPSVGVE----VPDVELECPDAKLKGPKFKMPEMHFKTPKISM 1991
               DV+VS+P +E D+  P   ++      D+ L   D   K  KFKMP+    +  +S 
Sbjct: 2273 TAPDVEVSLPSVEVDVKAPGAKLDGARLEGDMSLADKDVTAKDSKFKMPKFKMLSFGVSA 2332

Query: 1992 --PDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKMDID--APDVDVHGPDWHL- 2046
                ++       +K + DVS+P ++G++K  D+ ++ P  D++  A  VDV  P+  + 
Sbjct: 2333 LGKSIEASADVSALKVEADVSLPSMQGDLKTTDLSVQPPSADLEVQAGQVDVKLPEGPVP 2392

Query: 2047 -------KMPKMKMPKFSMPGFKAEGPEVDVNLPKADVVVSGPKVDVEVPD--------- 2090
                    +PK++MP F MP    +GP++DV  PK D  + GPK DV  PD         
Sbjct: 2393 EGAGLKGHLPKLQMPSFKMPKVDLKGPQIDVKGPKLD--LKGPKTDVMAPDVEVSQPSVE 2450

Query: 2091 VSLEGPEGKLKGPKLK-----------MPEMHFKAPKISMPDVDLHLKGPKVKGDVDVSL 2139
            V +E P  KL G  L+             +  FK PK  MP   +   G  ++  VDVS 
Sbjct: 2451 VDVEAPGAKLDGAWLEGDLSVADKDVTTKDSRFKIPKFKMPSFGVSAPGKSIEASVDVSA 2510

Query: 2140 PKLEGD----------------LTGPSVDVEVP--DVELECPD------AKLKG------ 2169
            PK+E D                +  PS D+EV    V+++ P+      A LKG      
Sbjct: 2511 PKVEADGSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGLKGHLPKVQ 2570

Query: 2170 -PKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMDVSVPKVEGEMKVPDVDIRGPKV--- 2225
             P FKMPEM  K P++ +    L+LKGPK     +V+ P VE  +   +VD++ P+    
Sbjct: 2571 MPSFKMPEMDLKGPQLDVKGPKLDLKGPKA----EVTAPDVEMSLSSMEVDVQAPRAKLD 2626

Query: 2226 ------DIDAPDVDVHGPDWHLKMPKMKMPKF------------------------SMPG 2255
                  D+   D  V   D   KMPK KMP F                        S+P 
Sbjct: 2627 GARLEGDLSLADKGVTAKDSKFKMPKFKMPSFRVSAPGESIEALVDVSELKVEADMSLPS 2686

Query: 2256 FKGEGPEVDVNL--PKADVDVSGPKVDVEVPD------VSLEGPEGKLKGPKFKMPEMHF 2307
             +G+    D+++  P A ++V   +VDV++P+        L+G   KL+ P FKMPE+  
Sbjct: 2687 MQGDLKTTDISIQPPSAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKLQMPSFKMPEVDL 2746

Query: 2308 KTPKISMPDVDFNLKGPKIK---GDVDVSAPKLEGELKGPELDVKGPKLDAD--MPEVAV 2362
            K P+I +   + +LKGPK +    DV +S   +E +++ P   + G +L+ D  + +  +
Sbjct: 2747 KGPQIDVKGPNVDLKGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGM 2806

Query: 2363 EGPNGKWKTPKFKMPDMHFKAP-------------KI----SMPDL-------DLHLKSP 2398
               + K+K PKFKMP     AP             K+    S P +       D+ ++ P
Sbjct: 2807 TAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSELKVEADGSFPSMQGDLKTTDIRIQPP 2866

Query: 2399 KAK-----GEVDVDVPK--------LEG---------------DLKGPHVDVSGPDIDIE 2430
             A+     G+VDV +P+        L+G               DLKGP +DV GP +D++
Sbjct: 2867 SAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLK 2926

Query: 2431 GP----------------------------------------------EGKLKGPKFKMP 2444
            GP                                              + K K PKFKMP
Sbjct: 2927 GPKAEVTAPDVEVSLPSVEVDVEAPRAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMP 2986

Query: 2445 DMHFKAPNISMPDVDLNLKGPKIKGDVDVSVPEVEGKLEVPDMNIRGP----KVDVNAPD 2500
                 AP  S+ +V +++  PK+  + +VS+P ++G L+  D++I  P    +V     D
Sbjct: 2987 SFGVSAPGKSI-EVSVDVSAPKV--EAEVSLPSMQGDLKTTDISIEPPSAQLEVQAGQVD 3043

Query: 2501 VQAPDWHL--------KMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDIEGPD 2552
            ++ P+ H+         +PK++MP F MP    +GP++DV  PK  +D+ GPK D+  PD
Sbjct: 3044 LKLPEGHVPEGAGLKGHLPKLQMPSFKMPKVDRKGPQIDVKGPK--LDLKGPKTDVTAPD 3101

Query: 2553 ---------VNIEGPEGKLKGPKLK-----------MPEMNIKAPKISMPDFDLHLKGPK 2592
                     V++E P  KL G +L+             +   K PK  MP F +   G  
Sbjct: 3102 VEVSQPGMEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKS 3161

Query: 2593 VKGDVDVSLPKVE---------GDLKGPEVDIKGP--KVDINAPDVGVQGPDWHL----- 2636
            ++  VDVS PKVE         GDLK  ++ I+ P  ++++ A  V V+ P+ H+     
Sbjct: 3162 IEVLVDVSAPKVEADLSLPSMQGDLKNTDISIEPPSAQLEVQAGQVDVKLPEGHVLEGAG 3221

Query: 2637 ---KMPKVKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPKVDIEGPDVNIEGP------- 2686
                +PK++MP F MP    +GP  D+K PK  +D+ GPK+D+  PDV +  P       
Sbjct: 3222 LKGHLPKLQMPSFKMPKVDRKGPQIDIKGPK--LDLKGPKMDVTAPDVEVSQPSMEVDVE 3279

Query: 2687 -------------------------EGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKV 2721
                                     + K K PKFKMP     AP  S+    +++  P  
Sbjct: 3280 APGAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSYRASAPGKSI-QASVDVSAP-- 3336

Query: 2722 KGDVDVSLPKVEGDLKGPEVDIKGPKVDID--APDVDVHGPDWHL--------KMPKIKM 2771
            K + DVSLP ++GDLK  ++ I+ P VD++  A  VDV  P+ H+         +PK++M
Sbjct: 3337 KAEADVSLPSMQGDLKTTDLSIQLPSVDLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVEM 3396

Query: 2772 PKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGP--EGKWKSPKFKM---- 2825
            P   MP    + P VD+  PK D+ V  PK +V  PDV +  P  E   ++P+ K+    
Sbjct: 3397 PSFKMPKVDLKSPQVDIKGPKLDLKV--PKAEVTVPDVEVSLPSVEVDVQAPRAKLDGAR 3454

Query: 2826 --------------PEMHFKTPKISMPDIDLNLTGPKIKGDVDVTGPKVE---------G 2862
                           +  FK PK  MP   ++  G  I+  +DV+ PKVE         G
Sbjct: 3455 LEGDLSLAEKDVTAKDSKFKMPKFKMPSFGVSAPGRSIEASLDVSAPKVEADVSLSSMQG 3514

Query: 2863 DLKGPEVDLKGPKVDIDVPDVNV----------QGPDWHLKMPKMKMPKFSMPGFKAEGP 2912
            DLK  ++ ++ P  D++V  V V          +G      +PK++MP    P    +GP
Sbjct: 3515 DLKATDLSIQPPSADLEVQAVQVDVELLEGPVPEGAGLKGHLPKVEMPSLKTPKVDLKGP 3574

Query: 2913 EVDVNLPKADVDVSGPKVDVEGPDVNIEGP------------------------------ 2942
            ++DV  PK  +D+ GPK +V  PDV +  P                              
Sbjct: 3575 QIDVKGPK--LDLKGPKAEVRVPDVEVSLPSVEVDVQAPKAKLDAGRLEGDLSLADKDVT 3632

Query: 2943 --EGKLKGPKFKMPEMNIKAPKIPMPDFDLHLKGPKVKGDVDISLPKVEGDLKGPEVDIR 3000
              + K K PKFKMP   + AP   M +  + +  PKV  + D+SLP ++GDLK  ++ I+
Sbjct: 3633 AKDSKFKMPKFKMPSFRVSAPGKSM-EASVDVSAPKV--EADVSLPSMQGDLKTTDLSIQ 3689

Query: 3001 GP---------QVDIDVPDVGV-QGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKAD 3050
             P         Q+D+ +P+  V +G      +PKV+MP   MP    +GP VD+  PK D
Sbjct: 3690 PPSADLKVQAGQMDVKLPEGQVPEGAGLKEHLPKVEMPSLKMPKVDLKGPQVDIKGPKLD 3749

Query: 3051 L-----DVSGPKVDIDVP--DVNIEGPEGKL-----------------------KGPKFK 3080
            L     +V+ P V++ +P  +V+++ P  KL                       K PKFK
Sbjct: 3750 LKVSKAEVTAPDVEVSLPSVEVDVQAPRAKLDSAQLEGDLSLADKDVTAKDSKFKMPKFK 3809

Query: 3081 MPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMKVPDVDIKGPKVD--INAPD 3138
            MP   + AP  S+ +  +++  PKV  + DVSLP ++GD+K  D+ I+    D  + A  
Sbjct: 3810 MPSFGVSAPGKSI-EASVHVSAPKV--EADVSLPSMQGDLKTTDLSIQPHSADLTVQARQ 3866

Query: 3139 VDVQGPDWHL--------KMPKIKMPKISMPGFKGEGPEVDVNLPKADL-----DVSGPK 3185
            VD++  + H+         +PK++MP   MP    +GPE+D+  PK DL     +V+ P 
Sbjct: 3867 VDMKLLEGHVPEEAGLKGHLPKVQMPSFKMPKVDLKGPEIDIKGPKLDLKDPKVEVTAPD 3926

Query: 3186 VDVDVP--DVNIEGPDAKLKG-----------------------PKFKMPEMNIKAPKIS 3220
            V+V +P  +V++E P AKL G                       PKFKMP   + AP  S
Sbjct: 3927 VEVSLPSVEVDVEAPGAKLDGARLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGKS 3986

Query: 3221 MPDLDLNLKGPKMKGEVDVSLANVEGDLKGPALDIKGPKID--VDAPDIDIHGPDAKL-K 3277
            M +  +++  PK+  E DVSL +++GDLK   L ++ P  D  V A  +D+  P+  + +
Sbjct: 3987 M-EASVDVTAPKV--EADVSLPSMQGDLKATDLSVQPPSADLEVQAGQVDVKLPEGPVPE 4043

Query: 3278 GPKLKMPDMHVNMPKISMPEIDLNLKGSKLKGDVDVSGPKLEGDIKAPSLDIKGPEVDVS 3337
            G  LK     V MP   MP++DL              GP++  D+K P LD+KGP+ +V+
Sbjct: 4044 GASLKGHLPKVQMPSFKMPKVDL-------------KGPQI--DVKGPKLDLKGPKAEVT 4088

Query: 3338 GPKLNIEGKSKKSRFKLPKFNFSGSKVQTPEVDVKGKKPDIDITGPKVDINAPDVEVQGK 3397
             P + +   S +              VQ P   + G + + D++    D+ A D     K
Sbjct: 4089 APDVKMSLSSME------------VDVQAPRAKLDGVQLEGDLSLADKDVTAKD----SK 4132

Query: 3398 VKGSKFKMPFLSISSPKVSMPDVELNLKSPKVKGDLDIAGPNLEGDFKGPKVDIKAPEVN 3457
             K  KFKMP   +S+P  SM   E ++   ++K   D++ P+++GD K   + I++P  +
Sbjct: 4133 FKMPKFKMPSFGVSAPGKSM---EASVDVSELKAKADVSLPSMQGDLKTTDLSIQSPSAD 4189

Query: 3458 L--NAPDVDVHGPDWNL-------------KMPKMKMPKFSVSG---------LKAEGPD 3493
            L   A  VDV  P+  L             +MP +KMPK ++ G         L  +GP 
Sbjct: 4190 LEVQAGQVDVKLPEGPLPKGAGLKGHLPKVQMPCLKMPKVALKGPQVDVKGPKLDLKGPK 4249

Query: 3494 -------VAVDLPKGDINIEGP-----SMNIEG----PDLNVEGPEGGLKGPKFKMPDMN 3537
                   V V LP  ++++E P     S+ +EG     D ++   +   K PKFKMP   
Sbjct: 4250 ADVMTPVVEVSLPSMEVDVEAPGAKLDSVRLEGDLSLADKDMTAKDSKFKMPKFKMPSFG 4309

Query: 3538 IKAPKISMPDIDLNLKGPKVKGDVDISLPKLEGDLKGPEVDIKGPKV---------DINA 3588
            + AP  S   I+ +L    +K + D+SLP ++GDLK   + I+ P           D+  
Sbjct: 4310 VSAPGKS---IEASLDVSALKVEADVSLPSMQGDLKTTHLSIQPPSADLEVQAGQEDVKL 4366

Query: 3589 PDVDVH-GPDWHLKMPKVKMPKFSMPGFKGEGPEVDVTLPKAD-----IDISGPNVDVDV 3642
            P+  VH G      +PK++MP F +P    +GP++DV +PK D     ++++ PN+DV +
Sbjct: 4367 PEGPVHEGAGLKGHLPKLQMPSFKVPKVDLKGPQIDVNVPKLDLKGPKVEVTSPNLDVSL 4426

Query: 3643 P--DVNIEGP-----------------------DAKLKGPKFKMPEMNIKAPKISMPDFD 3677
            P  +V+I+ P                       D+K K PKFKMP   + +P  S+ +  
Sbjct: 4427 PSMEVDIQAPGAKLDSTRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGMLSPGKSI-EVS 4485

Query: 3678 LNLKGPKMKGDVVVSLPKVEGDLKGPEVDIKGPKVDIDT--------------PDI-NIE 3722
            +++  PKM+ D  +S+P ++GDLK  ++ I+ P  D++               P++  ++
Sbjct: 4486 VDVSAPKMEAD--MSIPSMQGDLKTTDLRIQAPSADLEVQAGQVDLKLPEGHMPEVAGLK 4543

Query: 3723 GSEGKFKGPKFKIPEMHLKAPKISMPDIDLNLKGPKVK---GDVDVSLPKMEGDLKGPEV 3779
            G   K + P FK+P++ LK P++ +    L+LKGPK +    DV+VSLP +E D++ P  
Sbjct: 4544 GHLPKVEMPSFKMPKVDLKGPQVDVKGPKLDLKGPKAEVMAPDVEVSLPSVETDVQAPGS 4603

Query: 3780 DIKGPKV--DINAPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSG 3837
             + G ++  D++    DV G D      K + PK S  GF+     V ++  + + +V+ 
Sbjct: 4604 MLDGARLEGDLSLAHEDVAGKD-----SKFQGPKLSTSGFEWSSKKVSMSSSEIEGNVTF 4658

Query: 3838 PKVDIDVPDVNIEGPEGKLKGPK---------------FKMPEMNIKAPKISMPDIDLNL 3882
             +     P V     EG L  P                 K  +++ K PK+S        
Sbjct: 4659 HEKTSTFPIVESVVHEGDLHDPSRDGNLGLAVGEVGMDSKFKKLHFKVPKVSFSSTKTPK 4718

Query: 3883 KG--PKVKGDMDVS-------------LPKV----EGDMQVPD----------LDIKGPK 3913
                P  K  + +S             L +V    E  MQ+P           LD+ GP 
Sbjct: 4719 DSLVPGAKSSIGLSTIPLSSSECSSFELQQVSACSEPSMQMPKVGFAGFPSSRLDLTGPH 4778

Query: 3914 VD--INAPDVDVRGPDWHLKMPKIKM-PKISMPGFKGEGPEVDVNLPKAD--LDVSGPKV 3968
             +  I +P  DV    + + +P+  + P++++      G + D+ LPK +   D+  P+ 
Sbjct: 4779 FESSILSPCEDVTLTKYQVTVPRAALAPELALE--IPSGSQADIPLPKTECSTDLQPPE- 4835

Query: 3969 DVDVPDVNIEGPDAKLKG-----------PKFKMPEMNIKAPKISMPDFDLH------LK 4011
               VP    E     L             PKF  P+     P++++P+ DLH      + 
Sbjct: 4836 --GVPTSQAESHSGPLNSMIPVSLGQVSFPKFYKPKFVFSVPQMAVPEGDLHAAVGAPVM 4893

Query: 4012 GPKVKGD-VDVSLPKMEGD------LKAPEVDIKGPKVDIDAP------DVDVHGPDWHL 4058
             P   G+ V   LP  +         + PE  +   +  + AP      D D  G    L
Sbjct: 4894 SPLSPGERVQCPLPSTQLPSPGTCVSQGPEELVASLQTSVVAPGEAPSEDADHEGKGSPL 4953

Query: 4059 KMPKVKMPKFSMPGFKGEGPEVDVNLPKADIDVSGPKVDID----TPDIDIH-------- 4106
            KMPK+K+P F     K  GP+VD   P+  ++ S   + +D     P   IH        
Sbjct: 4954 KMPKIKLPSFRWSPKKETGPKVD---PECSVEDSKLSLVLDKDEVAPQSAIHMDLPPERD 5010

Query: 4107 GPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPE-VDI 4165
            G +G+   P F MP L L   K S   V L    P+   D  +S     G  +  E    
Sbjct: 5011 GEKGRSTKPGFAMPKLALPKMKASKSGVSL----PQRDVDPSLSSATAGGSFQDTEKASS 5066

Query: 4166 KGPKVDIDVPDVDVQGPDWHLKMPKVKMPK--FSMPGFKGEGPDVDVNLPKADLDVSGPK 4223
             G +  +            +L  P+V +P   F+ P         D+   KA ++VS P+
Sbjct: 5067 DGGRGGLGATASATGSEGVNLHRPQVHIPSLGFAKP---------DLRSSKAKVEVSQPE 5117

Query: 4224 VDIDVP--DVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPK 4281
             D+ +P  D++ EG D++  G                              GDV VS P 
Sbjct: 5118 ADLPLPKHDLSTEG-DSRGCG-----------------------------LGDVPVSQPC 5147

Query: 4282 VEGDLKGPEVDIKGPKVDIDAPDVDVHGPD-----WHLKMPKVKMPKFSMPGFKGEGPDV 4336
             EG    PE  ++      DA  + V  P+      + +    KMPKF MP  +    D 
Sbjct: 5148 GEGIAPTPEDPLQPSCRKPDAEVLTVESPEEEAMTKYSQESWFKMPKFRMPSLRRSFRDR 5207

Query: 4337 DVTLPKADIEISGPKVDIDAPDVSIEGPDAKLKGPKFKMPEMNIKAP-KISMPDIDFNLK 4395
                    +E++       AP  +  G +A  K  +F +   N++A   + +P+ D  + 
Sbjct: 5208 G---GAGKLEVA----QTQAP--AATGGEAAAKVKEFLVSGSNVEAAMSLQLPEADAEVT 5258

Query: 4396 GPKVKGDVDVSLPKVEGDLKGPEIDIKGPSL---DIDTPDVNIEGPEGKLKGPKFKMPEM 4452
              + K   D+   + + D  G ++ +    +   ++ T +V I   +G L    F+MP M
Sbjct: 5259 ASESKSSTDIL--RCDLDSTGLKLHLSTAGMTGDELSTSEVRIHPSKGPL---PFQMPGM 5313

Query: 4453 NIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVESDLKGPEVDIE----GPEG--KLKGPK 4506
             +   ++   + D            +  L K   DL   E   E     PEG  KLK   
Sbjct: 5314 RLPETQVLPGEID------------ETPLSKPGHDLASMEDKTEKWSSQPEGPLKLKASS 5361

Query: 4507 FKMPDVHFKSPQISMSDID-------LNLKGPKIK-GDMDISVPKLEGDLKGPKV-DVKG 4557
              MP       QIS+ ++D       L +K PK+         P  E D+  P V +V+ 
Sbjct: 5362 TDMPS------QISVVNVDQLWEDSVLTVKFPKLMVPRFSFPAPSSEDDVFIPTVREVQC 5415

Query: 4558 PKVGIDTP---------DIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKVK 4608
            P+  IDT             I      + G +    +L L+AP IS  +V ++++G +V+
Sbjct: 5416 PEANIDTALCKESPGLWGASILKAGAGVPGEQPVDLNLPLEAPPIS--KVRVHIQGAQVE 5473

Query: 4609 GDMDISLPKVEG----DLKGPEVDIRDPKVDIDVPDVDVQGPDWHLKMPKVKMPK 4659
               ++++  +      DL  P         + ++P  ++Q P +   + KVK+P+
Sbjct: 5474 -SQEVTIHSIVTPEFVDLSVPRTFSTQIVRESEIPTSEIQTPSYGFSLLKVKIPE 5527



 Score = 1511 bits (3912), Expect = 0.0
 Identities = 1362/4593 (29%), Positives = 2079/4593 (45%), Gaps = 1145/4593 (24%)

Query: 2292 EGKLKGPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVDVSAPKLEGELKGPELDVKGP 2351
            + K K PKFKMP      P  SM +   ++  PK+  + DVS   ++G+LK  +L V+ P
Sbjct: 672  DSKFKMPKFKMPLFGASAPGKSM-EASVDVSAPKV--EADVSLLSMQGDLKTTDLSVQTP 728

Query: 2352 KLDADMPEVAV----------EGPNGKWKTPKFKMPDMHFKAPKISMPDLDLHLKSPKAK 2401
              D ++ +  V          EG + K   PK + P +  K PK+ +    L LK PKA+
Sbjct: 729  SADLEVQDGQVDVKLPEGPLPEGASLKGHLPKVQRPSL--KMPKVDLKGPKLDLKGPKAE 786

Query: 2402 G------------EVDVDVPKLEGDLKGPHVDVSGPDIDIEGPEGKLKGPKFKMPDMHFK 2449
                         EVDV  P+ + D      D+S  D ++   + K K PKFKMP     
Sbjct: 787  VTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKEVTAKDSKFKMPKFKMPSFGVS 846

Query: 2450 APNISMPDVDLNLKGPKIKGDVDVSVPEVEGKLEVPDMNIRGP---------KVDVNAPD 2500
            AP  SM D  +++  PK++ DV +S   ++G L+  D++I+ P         +VDV  P+
Sbjct: 847  APGKSMED-SVDVSAPKVEADVSLS--SMQGDLKATDLSIQPPSADLEVQAGQVDVKLPE 903

Query: 2501 VQAPDW---HLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDIEGPD----- 2552
               P+     + +PK++MP F MP    +GP++DV  PK  +D+ GPK ++  PD     
Sbjct: 904  GPVPEGAGPKVHLPKVEMPSFKMPKVDLKGPQIDVKGPK--LDLKGPKAEVTAPDGEVSL 961

Query: 2553 ----VNIEGPEGKLKGPKLK-----------MPEMNIKAPKISMPDFDLHLKGPKVKGDV 2597
                V+++  + KL G  L+             +   K PK  MP F +   G  +K  V
Sbjct: 962  PSMEVDVQAQKAKLDGAWLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIKALV 1021

Query: 2598 DVSLPKVE---------GDLKGPEVDIKGPKVD--INAPDVGVQGPDWHLK--------M 2638
            DVS PKVE         GDLK  ++ I+    D  + A  V V+ P+ HL         +
Sbjct: 1022 DVSAPKVEADLSLPSMQGDLKTTDLSIQPASTDLKVQADQVDVKLPEGHLPEGAGLKGHL 1081

Query: 2639 PKVKMPKFSMPGFKGEGPDGDVKLPKADI-----DVSGPKVDIEGP--DVNIEGPEGKL- 2690
            PKV+MP F MP    +GP  DVK PK D+     +V+ P V++  P  +V++E P  KL 
Sbjct: 1082 PKVEMPSFKMPKVALKGPQVDVKGPKLDLKSPKAEVTAPDVEVSLPSVEVDVEAPGAKLD 1141

Query: 2691 ----------------------KGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDVS 2728
                                  K PKFKMP     AP  S+ +  +++  PKV  + DVS
Sbjct: 1142 SARLEGELSLADKDVTAKDSRFKMPKFKMPSFGASAPGKSI-EASVDVSAPKV--EADVS 1198

Query: 2729 LPKVEGDLKGPEVDIKGPKVDID--APDVDVHGPDWHLK--------MPKIKMPKISMPG 2778
            LP ++GDLK  ++ I+ P  D++  A  VDV   + H+         +PK++MP + MP 
Sbjct: 1199 LPSMQGDLKTTDLSIQPPSADLEVHAGQVDVKLLEGHVPEGAGFKGHLPKVQMPSLKMPK 1258

Query: 2779 FKGEGPDVDVNLPKADID------------VSGP--KVDVECPDVNIEGPE--------- 2815
               +GP V+V  PK D+             VS P  +VD++ P   ++G +         
Sbjct: 1259 VDLKGPQVEVRGPKLDLKGHKAEVTAHEVAVSLPSVEVDMQAPGAKLDGAQLDGDLSLAD 1318

Query: 2816 -------GKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPE 2868
                    K+K PKFKMP      P  S+ +  ++L+ PK++ D+ +  P ++GDLK  +
Sbjct: 1319 KDVTAKDSKFKMPKFKMPSFGVSAPGKSI-EASVDLSAPKVEADMSL--PSMQGDLKTTD 1375

Query: 2869 VDLKGPKVDIDVP----DVNV------QGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNL 2918
            + ++ P  D+++     DV +      +G      +PK++MP F +P    +GPE+D+  
Sbjct: 1376 LSIQPPSTDLELQAGQLDVKLPEGPVPEGAGLKGHLPKLQMPSFKVPKVDLKGPEIDIKG 1435

Query: 2919 PKAD-----VDVSGPKVDVEGP--DVNIEGPEGKLKGPKFK-----------MPEMNIKA 2960
            PK D     V+V+ P V+V  P  +V++E P  KL G + +             +   K 
Sbjct: 1436 PKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGGRLEEDMSLADKDLTTKDSKFKM 1495

Query: 2961 PKIPMPDFDLHLKGPKVKGDVDISLPKVE---------GDLKGPEVDIRGP--------- 3002
            PK  MP F +   G  ++  VD+S PKVE         GDLK  ++ I+ P         
Sbjct: 1496 PKFKMPSFGVSAPGKSIEASVDVSAPKVEADVSLPSMQGDLKATDLSIQPPSADLEVQAG 1555

Query: 3003 QVDIDVPDVGV-QGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDID 3061
            QVD+ +P+  V +G      +PKV+MP F MP    +GP +DV  PK  LD+ GPKV++ 
Sbjct: 1556 QVDVKLPEGPVSEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPK--LDLKGPKVEVT 1613

Query: 3062 VPDV---------NIEGPEGKLKG-----------------------PKFKMPEMNIKAP 3089
             PDV         +++ P  KL G                       PKFKMP   + AP
Sbjct: 1614 APDVKMSLSSMEVDVQAPRAKLDGAQLEGDLSLADKAVTAKDSKFKMPKFKMPSFGVSAP 1673

Query: 3090 KISMPDIDLNLKGPKVKGDMDVSLPKVEGDMKVPDVDIKGPKVD--INAPDVDVQGPDWH 3147
              S+ +  +++  PKV+ D  VSLP ++GD+K  D+ I+ P  D  + A  V+V+ P+  
Sbjct: 1674 GKSI-EASVDVSEPKVEAD--VSLPSMQGDLKTTDLSIQSPSADLEVQAGQVNVKLPEGP 1730

Query: 3148 LK--------MPKIKMPKISMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGP- 3198
            L         +PK++MP + MP    +GP++DV  PK  LD+ GPK +V  PDV +  P 
Sbjct: 1731 LPEGAGFKGHLPKVQMPSLKMPKVALKGPQMDVKGPK--LDLKGPKAEVMAPDVEVSLPS 1788

Query: 3199 -------------------------------DAKLKGPKFKMPEMNIKAPKISMPDLDLN 3227
                                           D+K K PKFKMP   + AP  S+ +  ++
Sbjct: 1789 VEVDVEAPGAKLDSVRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSI-EASVD 1847

Query: 3228 LKGPKMKGEVDVSLANVEGDLKGPALDIKGPKID--VDAPDIDIHGPDAKL-KGPKLKMP 3284
            +  PK+  E +VSL +++GDLK   L I  P  D  V A  +D+  P+ ++ +G  LK  
Sbjct: 1848 VSAPKV--EAEVSLPSMQGDLKTTDLCIPLPSADLVVQAGQVDMKLPEGQVPEGAGLKGH 1905

Query: 3285 DMHVNMPKISMPEIDLNLKGSKLKG-DVDVSGPKLEGDIKAPSLDIKGP--EVDVSGPKL 3341
               V+MP   MP++DL    + +KG  +D+ GPK E  + AP +++  P  EVDV   K 
Sbjct: 1906 LPKVDMPSFKMPKVDLKGPQTDVKGAKLDLKGPKAE--VTAPDVEVSLPSMEVDVQAQKA 1963

Query: 3342 NIEGK--------------SKKSRFKLPKFNFSGSKVQTP------EVDVKGKKPDIDIT 3381
             ++G               +K S+FK+PKF      V  P       VDV   K + D++
Sbjct: 1964 KLDGARLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGRSIEASVDVPAPKVEADVS 2023

Query: 3382 GPKV--DINAPDVEVQGKVKGSKFKMPFLSISSP----------KVSMPDVEL-NLKSPK 3428
             P +  D+   D+ +Q      K +   + +  P          K  +P VE+ +LK PK
Sbjct: 2024 LPSMQGDLKTTDLSIQPPSADLKVQTGQVDVKLPEGHVPEGAGLKGHLPKVEMPSLKMPK 2083

Query: 3429 VKGDLDIAGPNLEGDFKGPKVDIKAPEVNLNAPDVDVHGP-------------------- 3468
            V    D+ GP +  D KGPK+D+K P+V +  PDV+V  P                    
Sbjct: 2084 V----DLKGPQV--DIKGPKLDLKDPKVEMRVPDVEVSLPSMEVDVQAPRAKLDSAHLQG 2137

Query: 3469 ------------DWNLKMPKMKMPKFSVSGL-KAEGPDVAVDLPKGDINIEGPSM--NIE 3513
                        D   KMPK KMP F VS   K+    V V  PK + ++  PSM  +++
Sbjct: 2138 DLTLANKDLTTKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSPPKVEADMSLPSMQGDLK 2197

Query: 3514 GPDLNV-------------------EGP---EGGLKG-------PKFKMPDMNIKAPKIS 3544
              DL++                   EGP   E GLKG       P FK+P +++K P+I 
Sbjct: 2198 TTDLSIQPLSADVKVQAGQVDVKLLEGPVPEEVGLKGHLPKLQMPSFKVPKVDLKGPEID 2257

Query: 3545 MPDIDLNLKGPKVK---GDVDISLPKLEGDLKGPEVDIKGPKV--DINAPDVDVHGPDWH 3599
            +    L+LK PKV+    DV++SLP +E D+K P   + G ++  D++  D DV   D  
Sbjct: 2258 IKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVKAPGAKLDGARLEGDMSLADKDVTAKDSK 2317

Query: 3600 LKMPKVKMPKF------------------------SMPGFKGEGPEVDVTL--PKADIDI 3633
             KMPK KM  F                        S+P  +G+    D+++  P AD+++
Sbjct: 2318 FKMPKFKMLSFGVSALGKSIEASADVSALKVEADVSLPSMQGDLKTTDLSVQPPSADLEV 2377

Query: 3634 SGPNVDVDVPD------VNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLNLKGPK--- 3684
                VDV +P+        ++G   KL+ P FKMP++++K P+I +    L+LKGPK   
Sbjct: 2378 QAGQVDVKLPEGPVPEGAGLKGHLPKLQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKTDV 2437

Query: 3685 MKGDVVVSLPKVEGDLKGPEVDIKGPKV--DIDTPDINIEGSEGKFKGPKFKIPEMHLKA 3742
            M  DV VS P VE D++ P   + G  +  D+   D ++   + +FK PKFK+P   + A
Sbjct: 2438 MAPDVEVSQPSVEVDVEAPGAKLDGAWLEGDLSVADKDVTTKDSRFKIPKFKMPSFGVSA 2497

Query: 3743 PKISMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPEVDIKGPKVD--INAPDVDVQGPDW 3800
            P  S+ +  +++  PKV  + D SL  M+GDLK  ++ I+ P  D  + A  VDV+ P+ 
Sbjct: 2498 PGKSI-EASVDVSAPKV--EADGSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEG 2554

Query: 3801 HLK--------MPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDV----- 3847
             +         +PKV+MP F MP    +GP +DV  PK  LD+ GPK ++  PDV     
Sbjct: 2555 PVPEGAGLKGHLPKVQMPSFKMPEMDLKGPQLDVKGPK--LDLKGPKAEVTAPDVEMSLS 2612

Query: 3848 ----NIEGPEGKLKG-----------------------PKFKMPEMNIKAPKISMPDIDL 3880
                +++ P  KL G                       PKFKMP   + AP  S   I+ 
Sbjct: 2613 SMEVDVQAPRAKLDGARLEGDLSLADKGVTAKDSKFKMPKFKMPSFRVSAPGES---IEA 2669

Query: 3881 NLKGPKVKGDMDVSLPKVEGDMQVPDLDIKGP--KVDINAPDVDVRGPDWHLK------- 3931
             +   ++K + D+SLP ++GD++  D+ I+ P  ++++ A  VDV+ P+ H+        
Sbjct: 2670 LVDVSELKVEADMSLPSMQGDLKTTDISIQPPSAQLEVQAGQVDVKLPEGHVPEGAGLKG 2729

Query: 3932 -MPKIKMPKISMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDV---------NIEGPD 3981
             +PK++MP   MP    +GP++DV  P  DL   GPK +V  PDV         +++ P 
Sbjct: 2730 HLPKLQMPSFKMPEVDLKGPQIDVKGPNVDL--KGPKAEVTAPDVKMSLSSMEVDVQAPR 2787

Query: 3982 AKLKGPKFK-----------MPEMNIKAPKISMPDFDLHLKGPKVKGDVDVS-------- 4022
            AKL G + +             +   K PK  MP F +   G  ++  VDVS        
Sbjct: 2788 AKLDGARLEGDLSLADKGMTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSELKVEADG 2847

Query: 4023 -LPKMEGDLKAPEVDIKGP--KVDIDAPDVDVHGPDWHLK--------MPKVKMPKFSMP 4071
              P M+GDLK  ++ I+ P  ++++ A  VDV  P+ H+         +PKV+MP F MP
Sbjct: 2848 SFPSMQGDLKTTDIRIQPPSAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVQMPSFKMP 2907

Query: 4072 GFKGEGPEVDVNLPKADIDVSGPKVDIDTPDI---------DIHGPEGKLKG-------- 4114
                +GP++DV  PK  +D+ GPK ++  PD+         D+  P  KL G        
Sbjct: 2908 KVDLKGPQIDVKGPK--LDLKGPKAEVTAPDVEVSLPSVEVDVEAPRAKLDGARLEGDLS 2965

Query: 4115 ---------------PKFKMPDLHLKAPKISMPEVDLNLKGPKMKGDVDVSLPKVEGDLK 4159
                           PKFKMP   + AP  S+ EV +++  PK+  + +VSLP ++GDLK
Sbjct: 2966 LADKDVTAKDSKFKMPKFKMPSFGVSAPGKSI-EVSVDVSAPKV--EAEVSLPSMQGDLK 3022

Query: 4160 GPEVDIKGPKVDIDVP--DVDVQGPDWHLK--------MPKVKMPKFSMPGFKGEGPDVD 4209
              ++ I+ P   ++V    VD++ P+ H+         +PK++MP F MP    +GP +D
Sbjct: 3023 TTDISIEPPSAQLEVQAGQVDLKLPEGHVPEGAGLKGHLPKLQMPSFKMPKVDRKGPQID 3082

Query: 4210 VNLPKADLDVSGPKVDIDVPDVNIEGP--------------------------------D 4237
            V  PK  LD+ GPK D+  PDV +  P                                D
Sbjct: 3083 VKGPK--LDLKGPKTDVTAPDVEVSQPGMEVDVEAPGAKLDGARLEGDLSLADKDVTAKD 3140

Query: 4238 AKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGP- 4296
            +K K PKFKMP   + AP  S+ +  + +  PKV  + D+SLP ++GDLK  ++ I+ P 
Sbjct: 3141 SKFKMPKFKMPSFGVSAPGKSI-EVLVDVSAPKV--EADLSLPSMQGDLKNTDISIEPPS 3197

Query: 4297 -KVDIDAPDVDVHGPDWHL--------KMPKVKMPKFSMPGFKGEGPDVDVTLPKADIEI 4347
             ++++ A  VDV  P+ H+         +PK++MP F MP    +GP +D+  PK D++ 
Sbjct: 3198 AQLEVQAGQVDVKLPEGHVLEGAGLKGHLPKLQMPSFKMPKVDRKGPQIDIKGPKLDLK- 3256

Query: 4348 SGPKVDIDAPDVSIEGP--------------------------------DAKLKGPKFKM 4375
             GPK+D+ APDV +  P                                D+K K PKFKM
Sbjct: 3257 -GPKMDVTAPDVEVSQPSMEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKM 3315

Query: 4376 PEMNIKAPKISMPDIDFNLKGPKVKGDVDVSLPKVEGDLKGPEIDIKGPSLDIDTP--DV 4433
            P     AP  S+     ++  PK   + DVSLP ++GDLK  ++ I+ PS+D++     V
Sbjct: 3316 PSYRASAPGKSI-QASVDVSAPKA--EADVSLPSMQGDLKTTDLSIQLPSVDLEVQAGQV 3372

Query: 4434 NIEGPEG-------------KLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVK---GDV 4477
            +++ PEG             K++ P FKMP++++K+P++ +    L LK PK +    DV
Sbjct: 3373 DVKLPEGHVPEGAGLKGHLPKVEMPSFKMPKVDLKSPQVDIKGPKLDLKVPKAEVTVPDV 3432

Query: 4478 DVSLPKVESDLKGP----------------EVDIEGPEGKLKGPKFKMPDVHFKSPQISM 4521
            +VSLP VE D++ P                E D+   + K K PKFKMP     +P  S+
Sbjct: 3433 EVSLPSVEVDVQAPRAKLDGARLEGDLSLAEKDVTAKDSKFKMPKFKMPSFGVSAPGRSI 3492

Query: 4522 SDIDLNLKGPKIKGDMDISVPKLEGDLKG-------PKVDVKGPKVGIDTPDIDIHGPEG 4574
             +  L++  PK++ D+ +S   ++GDLK        P  D++   V +D   ++   PEG
Sbjct: 3493 -EASLDVSAPKVEADVSLS--SMQGDLKATDLSIQPPSADLEVQAVQVDVELLEGPVPEG 3549

Query: 4575 --------KLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKVK---GDMDISLPKVEGDLK 4623
                    K++ P  K P + LK P+I +    L+LKGPK +    D+++SLP VE D++
Sbjct: 3550 AGLKGHLPKVEMPSLKTPKVDLKGPQIDVKGPKLDLKGPKAEVRVPDVEVSLPSVEVDVQ 3609

Query: 4624 GPEVDIRDPKV--DIDVPDVDVQGPDWHLKMPKVKMPKF--SMPGFKGEGPDVDVNLPKA 4679
             P+  +   ++  D+ + D DV   D   KMPK KMP F  S PG K     VDV+ PK 
Sbjct: 3610 APKAKLDAGRLEGDLSLADKDVTAKDSKFKMPKFKMPSFRVSAPG-KSMEASVDVSAPKV 3668

Query: 4680 DIDVSGPKV--DVDVPDVNIEGPDAKLKG------------------------PKFKMPE 4713
            + DVS P +  D+   D++I+ P A LK                         PK +MP 
Sbjct: 3669 EADVSLPSMQGDLKTTDLSIQPPSADLKVQAGQMDVKLPEGQVPEGAGLKEHLPKVEMP- 3727

Query: 4714 MSIKAPKISMPDIDLNLKGPKVK----------GDVDVTLPKVEGDLKGPEADIKGPKV- 4762
             S+K PK+ +    +++KGPK+            DV+V+LP VE D++ P A +   ++ 
Sbjct: 3728 -SLKMPKVDLKGPQVDIKGPKLDLKVSKAEVTAPDVEVSLPSVEVDVQAPRAKLDSAQLE 3786

Query: 4763 -DINTPDVDVHGPDWHLKMPKVKMPKF--SMPGFKGEGPDVDVSLPKADIDVSGPKVDVD 4819
             D++  D DV   D   KMPK KMP F  S PG K     V VS PK + DVS P +  D
Sbjct: 3787 GDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPG-KSIEASVHVSAPKVEADVSLPSMQGD 3845

Query: 4820 IPDVNI---------------------EG---PDAKLKG-------PKFKMPEINIKAPK 4848
            +   ++                     EG    +A LKG       P FKMP++++K P+
Sbjct: 3846 LKTTDLSIQPHSADLTVQARQVDMKLLEGHVPEEAGLKGHLPKVQMPSFKMPKVDLKGPE 3905

Query: 4849 ISIPDVDLDLKGPKVK---GDFDVSVPKVEGTLKGPEVDLKGPRL---------DFEGPD 4896
            I I    LDLK PKV+    D +VS+P VE  ++ P   L G RL         D    D
Sbjct: 3906 IDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGARLEGDLSLADKDMTAKD 3965

Query: 4897 AKLSGPSLKMPSLEISAP--------KVTAPDVDLH---------LKAPKIGFSGP---- 4935
            +K   P  KMPS  +SAP         VTAP V+           LKA  +    P    
Sbjct: 3966 SKFKMPKFKMPSFGVSAPGKSMEASVDVTAPKVEADVSLPSMQGDLKATDLSVQPPSADL 4025

Query: 4936 KLEGGEVDLK---GPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKFGFGAKSPKADIK 4992
            +++ G+VD+K   GP  E  SL  H+         P V++P FK PK     K P+ D+K
Sbjct: 4026 EVQAGQVDVKLPEGPVPEGASLKGHL---------PKVQMPSFKMPKVDL--KGPQIDVK 4074

Query: 4993 SPSLDVTVPEAELNLETPEISVGGKGKKSKFKMPKIHMSGPKIKAKKQGFDLNVPGGEID 5052
             P LD+  P+AE+    P++ +     +   + P+  + G +++      D +V   +  
Sbjct: 4075 GPKLDLKGPKAEVT--APDVKMSLSSMEVDVQAPRAKLDGVQLEGDLSLADKDVTAKDSK 4132

Query: 5053 ASL---KAPDVDVNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEFDIKSPKFKAEAPLP 5109
              +   K P   V+  G      VDV   K K      +  P ++ D+K+     +  + 
Sbjct: 4133 FKMPKFKMPSFGVSAPGKSMEASVDVSELKAK----ADVSLPSMQGDLKT----TDLSIQ 4184

Query: 5110 SPKLEGELQAPDLELSLPAIHV-EGLDIKAKAPKVKMPDVDISVPKIEGDLKGPKVQANL 5168
            SP  + E+QA  +++ LP   + +G  +K   PKV+MP   + +PK+   LKGP+V    
Sbjct: 4185 SPSADLEVQAGQVDVKLPEGPLPKGAGLKGHLPKVQMPC--LKMPKVA--LKGPQVDVK- 4239

Query: 5169 GAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPSVGLEGP----DVDL 5224
              P ++++G  A V TP       +VS+P + V+++ P  K D  SV LEG     D D+
Sbjct: 4240 -GPKLDLKGPKADVMTP-----VVEVSLPSMEVDVEAPGAKLD--SVRLEGDLSLADKDM 4291

Query: 5225 QGPEAKIKFPKFSMPKIGI--PGVKMEGG------GAEVHAQLPSLEGDLRGP------- 5269
               ++K K PKF MP  G+  PG  +E          E    LPS++GDL+         
Sbjct: 4292 TAKDSKFKMPKFKMPSFGVSAPGKSIEASLDVSALKVEADVSLPSMQGDLKTTHLSIQPP 4351

Query: 5270 -----------DVKL-EGP---DVSLKG--PGVDLPSVNLSMPKVSGPDLDLN-----LK 5307
                       DVKL EGP      LKG  P + +PS  +    + GP +D+N     LK
Sbjct: 4352 SADLEVQAGQEDVKLPEGPVHEGAGLKGHLPKLQMPSFKVPKVDLKGPQIDVNVPKLDLK 4411

Query: 5308 GPSLK---GDLDASVPSMKV--HAPGLNLSGVG---------------------GKMQVG 5341
            GP ++    +LD S+PSM+V   APG  L                          K ++ 
Sbjct: 4412 GPKVEVTSPNLDVSLPSMEVDIQAPGAKLDSTRLEGDLSLADKDVTAKDSKFKMPKFKMP 4471

Query: 5342 GDGVKVPGIDATTKLNVGAP--DVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEG 5399
              G+  PG      ++V AP  +  +  PS+QGDL  + D++   +   + DL ++A + 
Sbjct: 4472 SFGMLSPGKSIEVSVDVSAPKMEADMSIPSMQGDLKTT-DLR---IQAPSADLEVQAGQV 4527

Query: 5400 SIKLPKMKLPQFG--------ISTPGSDL-HVNAKGPQVSGELKGPGVDVNLKGPR--IS 5448
             +KLP+  +P+          +  P   +  V+ KGPQV  ++KGP +D  LKGP+  + 
Sbjct: 4528 DLKLPEGHMPEVAGLKGHLPKVEMPSFKMPKVDLKGPQV--DVKGPKLD--LKGPKAEVM 4583

Query: 5449 APNVDFNLEGPKVKGSLGATGE-IKGPTVGGGL----------------PGIGVQGLEGN 5491
            AP+V+ +L  P V+  + A G  + G  + G L                P +   G E +
Sbjct: 4584 APDVEVSL--PSVETDVQAPGSMLDGARLEGDLSLAHEDVAGKDSKFQGPKLSTSGFEWS 4641

Query: 5492 LQMPGIKSSGCDVNL---------PGVNVKLPTGQISGPEIKG--GLKGSEVGFHGAAPD 5540
             +   + SS  + N+         P V   +  G +  P   G  GL   EVG       
Sbjct: 4642 SKKVSMSSSEIEGNVTFHEKTSTFPIVESVVHEGDLHDPSRDGNLGLAVGEVGMDSKFKK 4701

Query: 5541 ISVKGPAFNMASPESDFGINLKGPK--IKGGADVSGGVSAPDISLGEGHLSVKGSGGEWK 5598
            +  K P  + +S         K PK  +  GA  S G+S   +S  E           ++
Sbjct: 4702 LHFKVPKVSFSST--------KTPKDSLVPGAKSSIGLSTIPLSSSEC--------SSFE 4745

Query: 5599 GPQVSS----ALNLDTSKFAG----GLHFSGPKVEGGV---------------------- 5628
              QVS+    ++ +    FAG     L  +GP  E  +                      
Sbjct: 4746 LQQVSACSEPSMQMPKVGFAGFPSSRLDLTGPHFESSILSPCEDVTLTKYQVTVPRAALA 4805

Query: 5629 --------KGGQIGLQAPGLSVSG--------PQGHLESGSG-----------KVTFPKM 5661
                     G Q  +  P    S         P    ES SG           +V+FPK 
Sbjct: 4806 PELALEIPSGSQADIPLPKTECSTDLQPPEGVPTSQAESHSGPLNSMIPVSLGQVSFPKF 4865

Query: 5662 KIPKFTFSGRELVGRE------MGVDVHFPKAE--------------------------- 5688
              PKF FS  ++   E      +G  V  P +                            
Sbjct: 4866 YKPKFVFSVPQMAVPEGDLHAAVGAPVMSPLSPGERVQCPLPSTQLPSPGTCVSQGPEEL 4925

Query: 5689 -ASIQ--------AGAGDGEWEESEVKLKKSKIKMPKFNFSKPKGKGGVTGSPEASISGS 5739
             AS+Q        A + D + E     LK  KIK+P F +S PK + G    PE S+  S
Sbjct: 4926 VASLQTSVVAPGEAPSEDADHEGKGSPLKMPKIKLPSFRWS-PKKETGPKVDPECSVEDS 4984

Query: 5740 KGDL---KSSKASLGSLEGEAEAEASSPKGK-----FSLFKSKKPRHRSNSFSDEREFSG 5791
            K  L   K   A   ++  +   E    KG+     F++ K   P+ +++        SG
Sbjct: 4985 KLSLVLDKDEVAPQSAIHMDLPPERDGEKGRSTKPGFAMPKLALPKMKASK-------SG 5037

Query: 5792 PSTPTGTLEFEGGEVSLEGGKVKGKHGKLKFGTFGGLGSKSKGHYEVTGSDD-ETGKLQG 5850
             S P   ++      +  GG  +        G  GGLG+ +      TGS+     + Q 
Sbjct: 5038 VSLPQRDVD-PSLSSATAGGSFQDTEKASSDGGRGGLGATA----SATGSEGVNLHRPQV 5092

Query: 5851 SGVSLASKKSRLSSSSSNDSGNKVGIQLPEVEL 5883
               SL   K  L SS +     KV +  PE +L
Sbjct: 5093 HIPSLGFAKPDLRSSKA-----KVEVSQPEADL 5120



 Score = 1418 bits (3671), Expect = 0.0
 Identities = 1280/4459 (28%), Positives = 1980/4459 (44%), Gaps = 1121/4459 (25%)

Query: 2274 VSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVDVS 2333
            +  P++ V V D  L+ P+      K    E    TP+        +  G  +KG+    
Sbjct: 477  IGPPEIRVRVHD--LKTPKFAFSTEKEPERERRLSTPQRGKRQDASSKAGTGLKGEEVEG 534

Query: 2334 APKLEGELKGPELDVKGPKLDADM----------PEVAVEGPNGKWKTPKFKMPDMHFKA 2383
            A  + G       + +G + D +            +   E   G+ + PKFK+P + +  
Sbjct: 535  AGWMPGREPTTHAEAQGDEGDGEEGLQRTRITEEQDKGREDTEGQIRMPKFKIPSLGWSP 594

Query: 2384 PKISMPDLDLHLKSPKAKGEVDVDVPKLEGDLKGPHVDVSGPDIDIEGPEGKLKGPKFKM 2443
             K        H K+ + K   D +                      +G EG+      + 
Sbjct: 595  SK--------HTKTGREKATEDTE----------------------QGREGEATATADRR 624

Query: 2444 PDMHFKAPNISMPDVDLNLKGPKIKGDVDVSVPEVEGKLEVPDMNIRGPKVDVNAPDVQA 2503
                 +             +G K K D D      + +L   +  ++  ++ +   +V  
Sbjct: 625  EQRRTE-------------EGLKDKEDSDSMTNTTKIQLIHDEKRLKKEQI-LTEKEVAT 670

Query: 2504 PDWHLKMPKMKMPKF--SMPGFKAEGPEVDVNLPKADVDIS--GPKVDIEGPDVNIEGPE 2559
             D   KMPK KMP F  S PG   E   VDV+ PK + D+S    + D++  D++++ P 
Sbjct: 671  KDSKFKMPKFKMPLFGASAPGKSMEA-SVDVSAPKVEADVSLLSMQGDLKTTDLSVQTPS 729

Query: 2560 GKLKGPKLKMPEMNIKAPKISMPDFDLHLKG--PKVKGDVDVSLPKVEGDLKGPEVDIKG 2617
              L+   ++  ++++K P+  +P+    LKG  PKV+    + +PKV  DLKGP++D+KG
Sbjct: 730  ADLE---VQDGQVDVKLPEGPLPE-GASLKGHLPKVQRP-SLKMPKV--DLKGPKLDLKG 782

Query: 2618 PKVDINAPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPKVDIE 2677
            PK ++ APDV              KM   SM        + DV+ P+A +D +  + D+ 
Sbjct: 783  PKAEVTAPDV--------------KMSLSSM--------EVDVQAPRAKLDGARLEGDLS 820

Query: 2678 GPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGDLK 2737
              D  +   + K K PKFKMP   + AP  SM D  +++  PKV  + DVSL  ++GDLK
Sbjct: 821  LADKEVTAKDSKFKMPKFKMPSFGVSAPGKSMED-SVDVSAPKV--EADVSLSSMQGDLK 877

Query: 2738 GPEVDIKGPKVDID--APDVDVHGPDWHLKM---PKIKMPKISMPGFKG-----EGPDVD 2787
              ++ I+ P  D++  A  VDV  P+  +     PK+ +PK+ MP FK      +GP +D
Sbjct: 878  ATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGPKVHLPKVEMPSFKMPKVDLKGPQID 937

Query: 2788 VNLPKADIDVSGPKVDVECPDVNIEGP-------------EGKWKSPKFKMPEMH----- 2829
            V  PK  +D+ GPK +V  PD  +  P             +G W      + +       
Sbjct: 938  VKGPK--LDLKGPKAEVTAPDGEVSLPSMEVDVQAQKAKLDGAWLEGDLSLADKDVTAKD 995

Query: 2830 --FKTPKISMPDIDLNLTGPKIKGDVDVTGPKVE---------GDLKGPEVDLKGPKVDI 2878
              FK PK  MP   ++  G  IK  VDV+ PKVE         GDLK  ++ ++    D+
Sbjct: 996  SKFKMPKFKMPSFGVSAPGKSIKALVDVSAPKVEADLSLPSMQGDLKTTDLSIQPASTDL 1055

Query: 2879 DVP--DVNVQGPDWHLK--------MPKMKMPKFSMPGFKAEGPEVDVNLPKADV----- 2923
             V    V+V+ P+ HL         +PK++MP F MP    +GP+VDV  PK D+     
Sbjct: 1056 KVQADQVDVKLPEGHLPEGAGLKGHLPKVEMPSFKMPKVALKGPQVDVKGPKLDLKSPKA 1115

Query: 2924 DVSGPKVDVEGP--DVNIEGPEGKLKGPKFK-----------MPEMNIKAPKIPMPDFDL 2970
            +V+ P V+V  P  +V++E P  KL   + +             +   K PK  MP F  
Sbjct: 1116 EVTAPDVEVSLPSVEVDVEAPGAKLDSARLEGELSLADKDVTAKDSRFKMPKFKMPSFGA 1175

Query: 2971 HLKGPKVKGDVDISLPKVE---------GDLKGPEVDIRGPQVDIDVP----DVGV---- 3013
               G  ++  VD+S PKVE         GDLK  ++ I+ P  D++V     DV +    
Sbjct: 1176 SAPGKSIEASVDVSAPKVEADVSLPSMQGDLKTTDLSIQPPSADLEVHAGQVDVKLLEGH 1235

Query: 3014 --QGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLD------------VSGPKVD 3059
              +G  +   +PKV+MP   MP    +GP V+V  PK DL             VS P V+
Sbjct: 1236 VPEGAGFKGHLPKVQMPSLKMPKVDLKGPQVEVRGPKLDLKGHKAEVTAHEVAVSLPSVE 1295

Query: 3060 IDVP------------------DVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLK 3101
            +D+                   D ++   + K K PKFKMP   + AP  S+ +  ++L 
Sbjct: 1296 VDMQAPGAKLDGAQLDGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSI-EASVDLS 1354

Query: 3102 GPKVKGDMDVSLPKVEGDMKVPDVDIKGPKVDIN--APDVDVQGPDWHLK--------MP 3151
             PKV+ DM  SLP ++GD+K  D+ I+ P  D+   A  +DV+ P+  +         +P
Sbjct: 1355 APKVEADM--SLPSMQGDLKTTDLSIQPPSTDLELQAGQLDVKLPEGPVPEGAGLKGHLP 1412

Query: 3152 KIKMPKISMPGFKGEGPEVDVNLPKADL-----DVSGPKVDVDVP--DVNIEGPDAKLKG 3204
            K++MP   +P    +GPE+D+  PK DL     +V+ P V+V +P  +V++E P AKL G
Sbjct: 1413 KLQMPSFKVPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDG 1472

Query: 3205 -----------------------PKFKMPEMNIKAP-----------------KISMPDL 3224
                                   PKFKMP   + AP                  +S+P +
Sbjct: 1473 GRLEEDMSLADKDLTTKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSAPKVEADVSLPSM 1532

Query: 3225 -------DLNLKGPK-----MKGEVDVSL--------ANVEG------------------ 3246
                   DL+++ P        G+VDV L        A ++G                  
Sbjct: 1533 QGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVSEGAGLKGHLPKVQMPSFKMPKVDLK 1592

Query: 3247 ----DLKGPALDIKGPKIDVDAPDI---------DIHGPDAKLKGPKLK----------- 3282
                D+KGP LD+KGPK++V APD+         D+  P AKL G +L+           
Sbjct: 1593 GPQIDVKGPKLDLKGPKVEVTAPDVKMSLSSMEVDVQAPRAKLDGAQLEGDLSLADKAVT 1652

Query: 3283 MPDMHVNMPKISMPEIDLNLKGSKLKGDVDVSGPKLEGDIKAPSL--DIKGPEVDVSGPK 3340
              D    MPK  MP   ++  G  ++  VDVS PK+E D+  PS+  D+K  ++ +  P 
Sbjct: 1653 AKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSEPKVEADVSLPSMQGDLKTTDLSIQSPS 1712

Query: 3341 LNIEGKSKKSRFKLPK------FNFSGS--KVQTP------------EVDVKGKKPDIDI 3380
             ++E ++ +   KLP+        F G   KVQ P            ++DVKG  P +D+
Sbjct: 1713 ADLEVQAGQVNVKLPEGPLPEGAGFKGHLPKVQMPSLKMPKVALKGPQMDVKG--PKLDL 1770

Query: 3381 TGPKVDINAPDVEVQ-----------------------------------GKVKGSKFKM 3405
             GPK ++ APDVEV                                     K K  KFKM
Sbjct: 1771 KGPKAEVMAPDVEVSLPSVEVDVEAPGAKLDSVRLEGDLSLADKDVTAKDSKFKMPKFKM 1830

Query: 3406 PFLSISSPKVSMPDVELNLKSPKVKGDLDIAGPNLEGDFKGPKVDIKAPEVNL--NAPDV 3463
            P   +S+P  S+ +  +++ +PKV+ ++ +  P+++GD K   + I  P  +L   A  V
Sbjct: 1831 PSFGVSAPGKSI-EASVDVSAPKVEAEVSL--PSMQGDLKTTDLCIPLPSADLVVQAGQV 1887

Query: 3464 DVHGPDWNLK-------------MPKMKMPK--------------FSVSGLKAE--GPDV 3494
            D+  P+  +              MP  KMPK                + G KAE   PDV
Sbjct: 1888 DMKLPEGQVPEGAGLKGHLPKVDMPSFKMPKVDLKGPQTDVKGAKLDLKGPKAEVTAPDV 1947

Query: 3495 AVDLPKGDINIEGPSMNIEGP---------DLNVEGPEGGLKGPKFKMPDMNIKAPKISM 3545
             V LP  +++++     ++G          D ++   +   K PKFKMP   + AP  S+
Sbjct: 1948 EVSLPSMEVDVQAQKAKLDGARLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGRSI 2007

Query: 3546 PDIDLNLKGPKVKGDVDISLPKLEGDLKGPEVDIKGPKVDINAP--DVDVHGPDWHLK-- 3601
             +  +++  PKV+ DV  SLP ++GDLK  ++ I+ P  D+      VDV  P+ H+   
Sbjct: 2008 -EASVDVPAPKVEADV--SLPSMQGDLKTTDLSIQPPSADLKVQTGQVDVKLPEGHVPEG 2064

Query: 3602 ------MPKVKMPKFSMPGFKGEGPEVDVTLPKADIDISGPNVDVDVPDVNIEGP----- 3650
                  +PKV+MP   MP    +GP+VD+  PK  +D+  P V++ VPDV +  P     
Sbjct: 2065 AGLKGHLPKVEMPSLKMPKVDLKGPQVDIKGPK--LDLKDPKVEMRVPDVEVSLPSMEVD 2122

Query: 3651 ---------------------------DAKLKGPKFKMPEMNIKAPKISMPDFDLNLKGP 3683
                                       D+K K PKFKMP   + AP  S+ +  +++  P
Sbjct: 2123 VQAPRAKLDSAHLQGDLTLANKDLTTKDSKFKMPKFKMPSFGVSAPGKSI-EASVDVSPP 2181

Query: 3684 KMKGDVVVSLPKVEGDLKGPEVDIKGPKVDIDTP---------------DINIEGSEGKF 3728
            K++ D+  SLP ++GDLK  ++ I+    D+                  ++ ++G   K 
Sbjct: 2182 KVEADM--SLPSMQGDLKTTDLSIQPLSADVKVQAGQVDVKLLEGPVPEEVGLKGHLPKL 2239

Query: 3729 KGPKFKIPEMHLKAPKISMPDIDLNLKGPKVK---GDVDVSLPKMEGDLKGPEVDIKGPK 3785
            + P FK+P++ LK P+I +    L+LK PKV+    DV+VSLP +E D+K P   + G +
Sbjct: 2240 QMPSFKVPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVKAPGAKLDGAR 2299

Query: 3786 V--DINAPDVDVQGPDWHLKMPKVKMPKF------------------------SMPGFKG 3819
            +  D++  D DV   D   KMPK KM  F                        S+P  +G
Sbjct: 2300 LEGDMSLADKDVTAKDSKFKMPKFKMLSFGVSALGKSIEASADVSALKVEADVSLPSMQG 2359

Query: 3820 E--GPDVDVNLPKADLDVSGPKVDIDVPD------VNIEGPEGKLKGPKFKMPEMNIKAP 3871
            +    D+ V  P ADL+V   +VD+ +P+        ++G   KL+ P FKMP++++K P
Sbjct: 2360 DLKTTDLSVQPPSADLEVQAGQVDVKLPEGPVPEGAGLKGHLPKLQMPSFKMPKVDLKGP 2419

Query: 3872 KISMPDIDLNLKGPK---VKGDMDVSLPKVEGDMQVPDLDIKGPKV--DINAPDVDVRGP 3926
            +I +    L+LKGPK   +  D++VS P VE D++ P   + G  +  D++  D DV   
Sbjct: 2420 QIDVKGPKLDLKGPKTDVMAPDVEVSQPSVEVDVEAPGAKLDGAWLEGDLSVADKDVTTK 2479

Query: 3927 DWHLKMPKIKMPK--ISMPGFKGEGPEVDVNLPK-------------------------A 3959
            D   K+PK KMP   +S PG K     VDV+ PK                         A
Sbjct: 2480 DSRFKIPKFKMPSFGVSAPG-KSIEASVDVSAPKVEADGSLSSMQGDLKATDLSIQPPSA 2538

Query: 3960 DLDVSGPKVDVDVPD------VNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGP 4013
            DL+V   +VDV +P+        ++G   K++ P FKMPEM++K P++ +    L LKGP
Sbjct: 2539 DLEVQAGQVDVKLPEGPVPEGAGLKGHLPKVQMPSFKMPEMDLKGPQLDVKGPKLDLKGP 2598

Query: 4014 KVK---GDVDVSLPKMEGDLKAPEVDIKGPKV--DIDAPDVDVHGPDWHLKMPKVKMPKF 4068
            K +    DV++SL  ME D++AP   + G ++  D+   D  V   D   KMPK KMP F
Sbjct: 2599 KAEVTAPDVEMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGVTAKDSKFKMPKFKMPSF 2658

Query: 4069 ------------------------SMPGFKGEGPEVDVNL--PKADIDVSGPKVDIDTPD 4102
                                    S+P  +G+    D+++  P A ++V   +VD+  P+
Sbjct: 2659 RVSAPGESIEALVDVSELKVEADMSLPSMQGDLKTTDISIQPPSAQLEVQAGQVDVKLPE 2718

Query: 4103 IDIHGPEG--------KLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKMK---GDVDVSL 4151
               H PEG        KL+ P FKMP++ LK P+I +   +++LKGPK +    DV +SL
Sbjct: 2719 G--HVPEGAGLKGHLPKLQMPSFKMPEVDLKGPQIDVKGPNVDLKGPKAEVTAPDVKMSL 2776

Query: 4152 PKVEGDLKGPEVDIKGPKV--DIDVPDVDVQGPDWHLKMPKVKMPKF------------- 4196
              +E D++ P   + G ++  D+ + D  +   D   KMPK KMP F             
Sbjct: 2777 SSMEVDVQAPRAKLDGARLEGDLSLADKGMTAKDSKFKMPKFKMPSFGVSAPGKSIEASV 2836

Query: 4197 -----------SMPGFKGEGPDVDVNL--PKADLDVSGPKVDIDVPD------VNIEGPD 4237
                       S P  +G+    D+ +  P A L+V   +VD+ +P+        ++G  
Sbjct: 2837 DVSELKVEADGSFPSMQGDLKTTDIRIQPPSAQLEVQAGQVDVKLPEGHVPEGAGLKGHL 2896

Query: 4238 AKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVK---GDVDVSLPKVEGDLKGPEVDIK 4294
             K++ P FKMP++++K P+I +    L LKGPK +    DV+VSLP VE D++ P   + 
Sbjct: 2897 PKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDVEVSLPSVEVDVEAPRAKLD 2956

Query: 4295 GPKV--DIDAPDVDVHGPDWHLKMPKVKMPKF--SMPGFKGEGPDVDVTLPKADIEISGP 4350
            G ++  D+   D DV   D   KMPK KMP F  S PG K     VDV+ PK + E+S P
Sbjct: 2957 GARLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPG-KSIEVSVDVSAPKVEAEVSLP 3015

Query: 4351 KV--DIDAPDVSIEGPDA-----------------------------KLKGPKFKMPEMN 4379
             +  D+   D+SIE P A                             KL+ P FKMP+++
Sbjct: 3016 SMQGDLKTTDISIEPPSAQLEVQAGQVDLKLPEGHVPEGAGLKGHLPKLQMPSFKMPKVD 3075

Query: 4380 IKAPKISMPDIDFNLKGPKVK---GDVDVSLPKVEGDLKGPEIDIKGPSL--DIDTPDVN 4434
             K P+I +     +LKGPK      DV+VS P +E D++ P   + G  L  D+   D +
Sbjct: 3076 RKGPQIDVKGPKLDLKGPKTDVTAPDVEVSQPGMEVDVEAPGAKLDGARLEGDLSLADKD 3135

Query: 4435 IEGPEGKLKGPKFKMPEMNIKAP--------KISMPDFDLHLKGPKVKGDV---DVSL-- 4481
            +   + K K PKFKMP   + AP         +S P  +  L  P ++GD+   D+S+  
Sbjct: 3136 VTAKDSKFKMPKFKMPSFGVSAPGKSIEVLVDVSAPKVEADLSLPSMQGDLKNTDISIEP 3195

Query: 4482 PKVESDLKGPEVDIEGPEG-------------KLKGPKFKMPDVHFKSPQISMSDIDLNL 4528
            P  + +++  +VD++ PEG             KL+ P FKMP V  K PQI +    L+L
Sbjct: 3196 PSAQLEVQAGQVDVKLPEGHVLEGAGLKGHLPKLQMPSFKMPKVDRKGPQIDIKGPKLDL 3255

Query: 4529 KGPKIK---GDMDISVPKLEGDLKGPKVDVKGPKV--GIDTPDIDIHGPEGKLKGPKFKM 4583
            KGPK+     D+++S P +E D++ P   + G ++   +   D D+   + K K PKFKM
Sbjct: 3256 KGPKMDVTAPDVEVSQPSMEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKM 3315

Query: 4584 PDLHLKAPKISMPEVDLNLKGPKVKGDMDISLPKVEGDLKGPEVDIRDPKVDIDVP--DV 4641
            P     AP  S+ +  +++  PK + D  +SLP ++GDLK  ++ I+ P VD++V    V
Sbjct: 3316 PSYRASAPGKSI-QASVDVSAPKAEAD--VSLPSMQGDLKTTDLSIQLPSVDLEVQAGQV 3372

Query: 4642 DVQGPDWHLK--------MPKVKMPKFSMPGFKGEGPDVDVNLPKADIDVSGPKVDVDVP 4693
            DV+ P+ H+         +PKV+MP F MP    + P VD+  PK D+ V  PK +V VP
Sbjct: 3373 DVKLPEGHVPEGAGLKGHLPKVEMPSFKMPKVDLKSPQVDIKGPKLDLKV--PKAEVTVP 3430

Query: 4694 DVNIEGP--------------------------------DAKLKGPKFKMPEMSIKAPKI 4721
            DV +  P                                D+K K PKFKMP   + AP  
Sbjct: 3431 DVEVSLPSVEVDVQAPRAKLDGARLEGDLSLAEKDVTAKDSKFKMPKFKMPSFGVSAPGR 3490

Query: 4722 SMPDIDLNLKGPKVKGDVDVTLPKVEGDLKG-------PEADI----------------- 4757
            S+ +  L++  PKV  + DV+L  ++GDLK        P AD+                 
Sbjct: 3491 SI-EASLDVSAPKV--EADVSLSSMQGDLKATDLSIQPPSADLEVQAVQVDVELLEGPVP 3547

Query: 4758 -----------------KGPKVDINTPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDV 4800
                             K PKVD+  P +DV GP   LK PK ++            PDV
Sbjct: 3548 EGAGLKGHLPKVEMPSLKTPKVDLKGPQIDVKGPKLDLKGPKAEV----------RVPDV 3597

Query: 4801 DVSLPKADIDVSGPKV---------DVDIPDVNIEGPDAKLKGPKFKMPEINIKAPKISI 4851
            +VSLP  ++DV  PK          D+ + D ++   D+K K PKFKMP   + AP  S+
Sbjct: 3598 EVSLPSVEVDVQAPKAKLDAGRLEGDLSLADKDVTAKDSKFKMPKFKMPSFRVSAPGKSM 3657

Query: 4852 PDVDLDLKGPKVKGDFDVSVPKVEGTLKGPEVDLKGP---------RLDFEGPDA----- 4897
             +  +D+  PKV+ D  VS+P ++G LK  ++ ++ P         ++D + P+      
Sbjct: 3658 -EASVDVSAPKVEAD--VSLPSMQGDLKTTDLSIQPPSADLKVQAGQMDVKLPEGQVPEG 3714

Query: 4898 --------KLSGPSLKMPSLEISAPKVTAPDVDLHLKAPKIGFSGPKLEGG----EVDLK 4945
                    K+  PSLKMP +++  P+V      L LK  K   + P +E      EVD++
Sbjct: 3715 AGLKEHLPKVEMPSLKMPKVDLKGPQVDIKGPKLDLKVSKAEVTAPDVEVSLPSVEVDVQ 3774

Query: 4946 GPKVEAPSL----DVHMDSPDINIEGPDVKIPKFKKPKFGFGA--KSPKADI--KSPSL- 4996
             P+ +  S     D+ +   D+  +    K+PKFK P FG  A  KS +A +   +P + 
Sbjct: 3775 APRAKLDSAQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVHVSAPKVE 3834

Query: 4997 -DVTVPEAELNLETPEISV---------------------------GGKGKKSK-----F 5023
             DV++P  + +L+T ++S+                           G KG   K     F
Sbjct: 3835 ADVSLPSMQGDLKTTDLSIQPHSADLTVQARQVDMKLLEGHVPEEAGLKGHLPKVQMPSF 3894

Query: 5024 KMPKIHMSGPKIKAKKQGFDLNVPGGEI---DASLKAPDVDVNIAGPDAALK-------- 5072
            KMPK+ + GP+I  K    DL  P  E+   D  +  P V+V++  P A L         
Sbjct: 3895 KMPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGARLEGDL 3954

Query: 5073 -----------VDVKSPKTKKTMFGKMY---FPDVEFDIKSPKFKAEAPLPSPKLEGELQ 5118
                          K PK K   FG        +   D+ +PK +A+  LPS  ++G+L+
Sbjct: 3955 SLADKDMTAKDSKFKMPKFKMPSFGVSAPGKSMEASVDVTAPKVEADVSLPS--MQGDLK 4012

Query: 5119 APDLELSLPAIHVE-----------------GLDIKAKAPKVKMPDVDISVPKIEGDLKG 5161
            A DL +  P+  +E                 G  +K   PKV+MP     +PK+  DLKG
Sbjct: 4013 ATDLSVQPPSADLEVQAGQVDVKLPEGPVPEGASLKGHLPKVQMPS--FKMPKV--DLKG 4068

Query: 5162 PKVQANLGAPDINIEGLDAKVKTPS--FGISAPQVSIPDVNVNLKGPKIKGDVPSVGLEG 5219
            P++      P ++++G  A+V  P     +S+ +V +      L G +++GD     L  
Sbjct: 4069 PQIDVK--GPKLDLKGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGVQLEGD-----LSL 4121

Query: 5220 PDVDLQGPEAKIKFPKFSMPKIGI--PGVKMEGG------GAEVHAQLPSLEGDLRGPDV 5271
             D D+   ++K K PKF MP  G+  PG  ME         A+    LPS++GDL+  D+
Sbjct: 4122 ADKDVTAKDSKFKMPKFKMPSFGVSAPGKSMEASVDVSELKAKADVSLPSMQGDLKTTDL 4181

Query: 5272 KLEGPDVSL-----------------KGPGVD--LPSVN---LSMPKVS--GPDLD---- 5303
             ++ P   L                 KG G+   LP V    L MPKV+  GP +D    
Sbjct: 4182 SIQSPSADLEVQAGQVDVKLPEGPLPKGAGLKGHLPKVQMPCLKMPKVALKGPQVDVKGP 4241

Query: 5304 -LNLKGPS---LKGDLDASVPSMKV--HAPGLNLSGVG---------------------G 5336
             L+LKGP    +   ++ S+PSM+V   APG  L  V                       
Sbjct: 4242 KLDLKGPKADVMTPVVEVSLPSMEVDVEAPGAKLDSVRLEGDLSLADKDMTAKDSKFKMP 4301

Query: 5337 KMQVGGDGVKVPGIDATTKLNVGA----PDVTLRGPSLQGDLAVSGDIKCPKVSVGAP-- 5390
            K ++   GV  PG      L+V A     DV+L  PS+QGDL      K   +S+  P  
Sbjct: 4302 KFKMPSFGVSAPGKSIEASLDVSALKVEADVSL--PSMQGDL------KTTHLSIQPPSA 4353

Query: 5391 DLSLEASEGSIKLP---------------KMKLPQFGISTPGSDLHVNAKGPQVSG---- 5431
            DL ++A +  +KLP               K+++P F +        V+ KGPQ+      
Sbjct: 4354 DLEVQAGQEDVKLPEGPVHEGAGLKGHLPKLQMPSFKVPK------VDLKGPQIDVNVPK 4407

Query: 5432 -ELKGPGVDVNLKGPRISAPNVDFNLEGPKVK-GSLGATGEIKGPTVGGGLPGIGVQGLE 5489
             +LKGP V+V      +S P+++ +++ P  K  S    G++        L    V   +
Sbjct: 4408 LDLKGPKVEVTSPNLDVSLPSMEVDIQAPGAKLDSTRLEGDLS-------LADKDVTAKD 4460

Query: 5490 GNLQMPGIKSSGCDVNLPGVNVKLPT--------GQISGPEIKGGLKGSEVGFHGAAPDI 5541
               +MP  K     +  PG ++++            +S P ++G LK +++     + D+
Sbjct: 4461 SKFKMPKFKMPSFGMLSPGKSIEVSVDVSAPKMEADMSIPSMQGDLKTTDLRIQAPSADL 4520

Query: 5542 SVKGPAFNMASPESDFG--INLKG--PKIKGGADVSGGVS--APDISLGEGHLSVKGSGG 5595
             V+    ++  PE        LKG  PK++  +     V    P + +    L +KG   
Sbjct: 4521 EVQAGQVDLKLPEGHMPEVAGLKGHLPKVEMPSFKMPKVDLKGPQVDVKGPKLDLKGPKA 4580

Query: 5596 EWKGPQVSSAL-NLDTSKFAGGLHFSGPKVEGG-------VKGGQIGLQAPGLSVSGPQG 5647
            E   P V  +L +++T   A G    G ++EG        V G     Q P LS SG + 
Sbjct: 4581 EVMAPDVEVSLPSVETDVQAPGSMLDGARLEGDLSLAHEDVAGKDSKFQGPKLSTSGFEW 4640

Query: 5648 HLESGS-------GKVTFPKMKIPKFTFSGRELVGREMGVDVHFPKAEASIQAGAGDGEW 5700
              +  S       G VTF +      TF   E V  E   D+H P  + ++    G+   
Sbjct: 4641 SSKKVSMSSSEIEGNVTFHEKTS---TFPIVESVVHEG--DLHDPSRDGNLGLAVGEVGM 4695

Query: 5701 EESEVKLKKSKIKMPKFNFSKPK-GKGGVTGSPEASISGSKGDLKSSKAS---LGSLEGE 5756
            +    K KK   K+PK +FS  K  K  +    ++SI  S   L SS+ S   L  +   
Sbjct: 4696 DS---KFKKLHFKVPKVSFSSTKTPKDSLVPGAKSSIGLSTIPLSSSECSSFELQQVSAC 4752

Query: 5757 AEAEASSPKGKFSLFKSKK 5775
            +E     PK  F+ F S +
Sbjct: 4753 SEPSMQMPKVGFAGFPSSR 4771



 Score = 1358 bits (3514), Expect = 0.0
 Identities = 1207/4111 (29%), Positives = 1857/4111 (45%), Gaps = 1059/4111 (25%)

Query: 2637 KMPKVKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKLKGPKFK 2696
            K  K KMPKF MP F    P    K  +A +DVS PKV+    DV++   +G LK     
Sbjct: 671  KDSKFKMPKFKMPLFGASAPG---KSMEASVDVSAPKVEA---DVSLLSMQGDLK----- 719

Query: 2697 MPEMNIKAPKISMP----DIDLNL-KGPKVKG-DVDVSLPKVEG-DLKGPEVDIKGPKVD 2749
              +++++ P   +      +D+ L +GP  +G  +   LPKV+   LK P+VD+KGPK+D
Sbjct: 720  TTDLSVQTPSADLEVQDGQVDVKLPEGPLPEGASLKGHLPKVQRPSLKMPKVDLKGPKLD 779

Query: 2750 IDAPDVDVHGPDWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDV 2809
            +  P  +V  PD       +KM   SM        +VDV  P+A +D +  + D+   D 
Sbjct: 780  LKGPKAEVTAPD-------VKMSLSSM--------EVDVQAPRAKLDGARLEGDLSLADK 824

Query: 2810 NIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPEV 2869
             +   + K+K PKFKMP      P  SM D  ++++ PK++ DV ++   ++GDLK  ++
Sbjct: 825  EVTAKDSKFKMPKFKMPSFGVSAPGKSMED-SVDVSAPKVEADVSLSS--MQGDLKATDL 881

Query: 2870 DLKGPKVDIDVPDVNVQ------------GPDWHLKMPKMKMPKFSMPGFKAEGPEVDVN 2917
             ++ P  D++V    V             GP  HL  PK++MP F MP    +GP++DV 
Sbjct: 882  SIQPPSADLEVQAGQVDVKLPEGPVPEGAGPKVHL--PKVEMPSFKMPKVDLKGPQIDVK 939

Query: 2918 LPKADVDVSGPKVDVEGPD---------VNIEGPEGKLKGPKFK-----------MPEMN 2957
             PK  +D+ GPK +V  PD         V+++  + KL G   +             +  
Sbjct: 940  GPK--LDLKGPKAEVTAPDGEVSLPSMEVDVQAQKAKLDGAWLEGDLSLADKDVTAKDSK 997

Query: 2958 IKAPKIPMPDFDLHLKGPKVKGDVDISLPKVE---------GDLKGPEVDIRGPQVDIDV 3008
             K PK  MP F +   G  +K  VD+S PKVE         GDLK  ++ I+    D+ V
Sbjct: 998  FKMPKFKMPSFGVSAPGKSIKALVDVSAPKVEADLSLPSMQGDLKTTDLSIQPASTDLKV 1057

Query: 3009 P--DVGVQGPDWHLK--------MPKVKMPKFSMPGFKGEGPDVDVNLPKADL-----DV 3053
                V V+ P+ HL         +PKV+MP F MP    +GP VDV  PK DL     +V
Sbjct: 1058 QADQVDVKLPEGHLPEGAGLKGHLPKVEMPSFKMPKVALKGPQVDVKGPKLDLKSPKAEV 1117

Query: 3054 SGPKVDIDVP--DVNIEGPEGKL-----------------------KGPKFKMPEMNIKA 3088
            + P V++ +P  +V++E P  KL                       K PKFKMP     A
Sbjct: 1118 TAPDVEVSLPSVEVDVEAPGAKLDSARLEGELSLADKDVTAKDSRFKMPKFKMPSFGASA 1177

Query: 3089 PKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMKVPDVDIKGPKVD--INAPDVDVQGPDW 3146
            P  S+ +  +++  PKV+ D  VSLP ++GD+K  D+ I+ P  D  ++A  VDV+  + 
Sbjct: 1178 PGKSI-EASVDVSAPKVEAD--VSLPSMQGDLKTTDLSIQPPSADLEVHAGQVDVKLLEG 1234

Query: 3147 HLK--------MPKIKMPKISMPGFKGEGPEVDVNLPKADLD------------VSGPKV 3186
            H+         +PK++MP + MP    +GP+V+V  PK DL             VS P V
Sbjct: 1235 HVPEGAGFKGHLPKVQMPSLKMPKVDLKGPQVEVRGPKLDLKGHKAEVTAHEVAVSLPSV 1294

Query: 3187 DVDVP------------------DVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDLDLNL 3228
            +VD+                   D ++   D+K K PKFKMP   + AP  S+ +  ++L
Sbjct: 1295 EVDMQAPGAKLDGAQLDGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSI-EASVDL 1353

Query: 3229 KGPKMKGEVDVSLANVEGDLKGPALDIKGPKIDVD--APDIDIHGPD------AKLKG-- 3278
              PK+  E D+SL +++GDLK   L I+ P  D++  A  +D+  P+      A LKG  
Sbjct: 1354 SAPKV--EADMSLPSMQGDLKTTDLSIQPPSTDLELQAGQLDVKLPEGPVPEGAGLKGHL 1411

Query: 3279 PKLKMPDMHVNMPKISMPEID-----LNLKGSKLK---GDVDVSGPKLEGDIKAPSLDIK 3330
            PKL+MP   V    +  PEID     L+LK  K++    DV+VS P +E D++AP   + 
Sbjct: 1412 PKLQMPSFKVPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLD 1471

Query: 3331 GPEVDVSGPKLNIEGKSKKSRFKLPKFNFSGSKVQTP------EVDVKGKKPDIDITGPK 3384
            G  ++      + +  +K S+FK+PKF      V  P       VDV   K + D++ P 
Sbjct: 1472 GGRLEEDMSLADKDLTTKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSAPKVEADVSLPS 1531

Query: 3385 V--DINAPDVEVQG-----KVKGSKF--KMPFLSISS--------PKVSMPDVEL---NL 3424
            +  D+ A D+ +Q      +V+  +   K+P   +S         PKV MP  ++   +L
Sbjct: 1532 MQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVSEGAGLKGHLPKVQMPSFKMPKVDL 1591

Query: 3425 KSPKVKGDLDIAGPNLEGDFKGPKVDIKAPEV--NLNAPDVDVHGP-------------- 3468
            K P++    D+ GP L  D KGPKV++ AP+V  +L++ +VDV  P              
Sbjct: 1592 KGPQI----DVKGPKL--DLKGPKVEVTAPDVKMSLSSMEVDVQAPRAKLDGAQLEGDLS 1645

Query: 3469 ---------DWNLKMPKMKMPKFSVS--GLKAEG---------------PDVAVDLPKGD 3502
                     D   KMPK KMP F VS  G   E                P +  DL   D
Sbjct: 1646 LADKAVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSEPKVEADVSLPSMQGDLKTTD 1705

Query: 3503 INIEGPSMNIE--GPDLNVEGPEG------GLKG-------PKFKMPDMNIKAPKISMPD 3547
            ++I+ PS ++E     +NV+ PEG      G KG       P  KMP + +K P++ +  
Sbjct: 1706 LSIQSPSADLEVQAGQVNVKLPEGPLPEGAGFKGHLPKVQMPSLKMPKVALKGPQMDVKG 1765

Query: 3548 IDLNLKGPKVK---GDVDISLPKLEGDLKGPEVDIKGPKV--DINAPDVDVHGPDWHLKM 3602
              L+LKGPK +    DV++SLP +E D++ P   +   ++  D++  D DV   D   KM
Sbjct: 1766 PKLDLKGPKAEVMAPDVEVSLPSVEVDVEAPGAKLDSVRLEGDLSLADKDVTAKDSKFKM 1825

Query: 3603 PKVKMPKF------------------------SMPGFKGEGPEVD--VTLPKADIDISGP 3636
            PK KMP F                        S+P  +G+    D  + LP AD+ +   
Sbjct: 1826 PKFKMPSFGVSAPGKSIEASVDVSAPKVEAEVSLPSMQGDLKTTDLCIPLPSADLVVQAG 1885

Query: 3637 NVDVDVPD------VNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLNLKGPKMK---G 3687
             VD+ +P+        ++G   K+  P FKMP++++K P+  +    L+LKGPK +    
Sbjct: 1886 QVDMKLPEGQVPEGAGLKGHLPKVDMPSFKMPKVDLKGPQTDVKGAKLDLKGPKAEVTAP 1945

Query: 3688 DVVVSLPKVEGDLKGPEVDIKGPKV--DIDTPDINIEGSEGKFKGPKFKIPEMHLKAPKI 3745
            DV VSLP +E D++  +  + G ++  D+   D ++   + KFK PKFK+P   + AP  
Sbjct: 1946 DVEVSLPSMEVDVQAQKAKLDGARLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGR 2005

Query: 3746 SMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPEVDIKGPKVDINAP--DVDVQGPDWHLK 3803
            S+ +  +++  PKV  + DVSLP M+GDLK  ++ I+ P  D+      VDV+ P+ H+ 
Sbjct: 2006 SI-EASVDVPAPKV--EADVSLPSMQGDLKTTDLSIQPPSADLKVQTGQVDVKLPEGHVP 2062

Query: 3804 --------MPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGP--- 3852
                    +PKV+MP   MP    +GP VD+  PK  LD+  PKV++ VPDV +  P   
Sbjct: 2063 EGAGLKGHLPKVEMPSLKMPKVDLKGPQVDIKGPK--LDLKDPKVEMRVPDVEVSLPSME 2120

Query: 3853 -----------------------------EGKLKGPKFKMPEMNIKAPKISMPDIDLNLK 3883
                                         + K K PKFKMP   + AP  S+ +  +++ 
Sbjct: 2121 VDVQAPRAKLDSAHLQGDLTLANKDLTTKDSKFKMPKFKMPSFGVSAPGKSI-EASVDVS 2179

Query: 3884 GPKVKGDMDVSLPKVEGDMQVPDLDIKGPKVDIN--APDVDVR---GP---DWHLK--MP 3933
             PKV+ DM  SLP ++GD++  DL I+    D+   A  VDV+   GP   +  LK  +P
Sbjct: 2180 PPKVEADM--SLPSMQGDLKTTDLSIQPLSADVKVQAGQVDVKLLEGPVPEEVGLKGHLP 2237

Query: 3934 KIKMPKISMPGFKGEGPEVDVNLPKADL-----DVSGPKVDVDVP--DVNIEGPDAKLKG 3986
            K++MP   +P    +GPE+D+  PK DL     +V+ P V+V +P  +V+++ P AKL G
Sbjct: 2238 KLQMPSFKVPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVKAPGAKLDG 2297

Query: 3987 PKFK-----------MPEMNIKAPKISMPDFDLHLKGPKV---------KGDVDVSLPKM 4026
             + +             +   K PK  M  F +   G  +         K + DVSLP M
Sbjct: 2298 ARLEGDMSLADKDVTAKDSKFKMPKFKMLSFGVSALGKSIEASADVSALKVEADVSLPSM 2357

Query: 4027 EGDLKAPEVDIKGPKVDID--APDVDVHGPDWHLK--------MPKVKMPKFSMPGFKGE 4076
            +GDLK  ++ ++ P  D++  A  VDV  P+  +         +PK++MP F MP    +
Sbjct: 2358 QGDLKTTDLSVQPPSADLEVQAGQVDVKLPEGPVPEGAGLKGHLPKLQMPSFKMPKVDLK 2417

Query: 4077 GPEVDVNLPKADIDVSGPKVDIDTPDI---------DIHGPEGKLKGPKFK--------- 4118
            GP++DV  PK  +D+ GPK D+  PD+         D+  P  KL G   +         
Sbjct: 2418 GPQIDVKGPK--LDLKGPKTDVMAPDVEVSQPSVEVDVEAPGAKLDGAWLEGDLSVADKD 2475

Query: 4119 --MPDLHLKAPKISMPEVDLNLKGPKMKGDVDVSLPKVE---------GDLKGPEVDIKG 4167
                D   K PK  MP   ++  G  ++  VDVS PKVE         GDLK  ++ I+ 
Sbjct: 2476 VTTKDSRFKIPKFKMPSFGVSAPGKSIEASVDVSAPKVEADGSLSSMQGDLKATDLSIQP 2535

Query: 4168 PKVDIDVP--DVDVQGPDWHLK--------MPKVKMPKFSMPGFKGEGPDVDVNLPKADL 4217
            P  D++V    VDV+ P+  +         +PKV+MP F MP    +GP +DV  PK  L
Sbjct: 2536 PSADLEVQAGQVDVKLPEGPVPEGAGLKGHLPKVQMPSFKMPEMDLKGPQLDVKGPK--L 2593

Query: 4218 DVSGPKVDIDVPDV---------NIEGPDAKLKGPKFK-----------MPEMNIKAPKI 4257
            D+ GPK ++  PDV         +++ P AKL G + +             +   K PK 
Sbjct: 2594 DLKGPKAEVTAPDVEMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGVTAKDSKFKMPKF 2653

Query: 4258 SMPDFDLHLKGPKVKGDVDVS---------LPKVEGDLKGPEVDIKGP--KVDIDAPDVD 4306
             MP F +   G  ++  VDVS         LP ++GDLK  ++ I+ P  ++++ A  VD
Sbjct: 2654 KMPSFRVSAPGESIEALVDVSELKVEADMSLPSMQGDLKTTDISIQPPSAQLEVQAGQVD 2713

Query: 4307 VHGPDWHLK--------MPKVKMPKFSMPGFKGEGPDVDVTLPKADIEISGPKVDIDAPD 4358
            V  P+ H+         +PK++MP F MP    +GP +DV  P  D++  GPK ++ APD
Sbjct: 2714 VKLPEGHVPEGAGLKGHLPKLQMPSFKMPEVDLKGPQIDVKGPNVDLK--GPKAEVTAPD 2771

Query: 4359 VS---------IEGPDAKLKG-----------------------PKFKMPEMNIKAPKIS 4386
            V          ++ P AKL G                       PKFKMP   + AP  S
Sbjct: 2772 VKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGMTAKDSKFKMPKFKMPSFGVSAPGKS 2831

Query: 4387 MPDIDFNLKGPKVKGDVDVSLPKVEGDLKGPEIDIKGPS--LDIDTPDVNIEGPEG---- 4440
               I+ ++   ++K + D S P ++GDLK  +I I+ PS  L++    V+++ PEG    
Sbjct: 2832 ---IEASVDVSELKVEADGSFPSMQGDLKTTDIRIQPPSAQLEVQAGQVDVKLPEGHVPE 2888

Query: 4441 ---------KLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVK---GDVDVSLPKVE--- 4485
                     K++ P FKMP++++K P+I +    L LKGPK +    DV+VSLP VE   
Sbjct: 2889 GAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDVEVSLPSVEVDV 2948

Query: 4486 -------------SDLKGPEVDIEGPEGKLKGPKFKMPDVHFKSPQISMSDIDLNLKGPK 4532
                          DL   + D+   + K K PKFKMP     +P  S+ ++ +++  PK
Sbjct: 2949 EAPRAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSI-EVSVDVSAPK 3007

Query: 4533 IKGDMDISVPKLEGDLKGPKVDVKGPKVGIDTP--DIDIHGPEG-------------KLK 4577
            ++ +  +S+P ++GDLK   + ++ P   ++     +D+  PEG             KL+
Sbjct: 3008 VEAE--VSLPSMQGDLKTTDISIEPPSAQLEVQAGQVDLKLPEGHVPEGAGLKGHLPKLQ 3065

Query: 4578 GPKFKMPDLHLKAPKISMPEVDLNLKGPKVKGDMDISLPKVEGDLKGPEVDIRDPKV--- 4634
             P FKMP +  K P+I +    L+LKGPK     D++ P VE    G EVD+  P     
Sbjct: 3066 MPSFKMPKVDRKGPQIDVKGPKLDLKGPKT----DVTAPDVEVSQPGMEVDVEAPGAKLD 3121

Query: 4635 ------DIDVPDVDVQGPDWHLKMPKVKMPKF------------------------SMPG 4664
                  D+ + D DV   D   KMPK KMP F                        S+P 
Sbjct: 3122 GARLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEVLVDVSAPKVEADLSLPS 3181

Query: 4665 FKGEGPDVDVNL--PKADIDVSGPKVDVDVPD------VNIEGPDAKLKGPKFKMPEMSI 4716
             +G+  + D+++  P A ++V   +VDV +P+        ++G   KL+ P FKMP++  
Sbjct: 3182 MQGDLKNTDISIEPPSAQLEVQAGQVDVKLPEGHVLEGAGLKGHLPKLQMPSFKMPKVDR 3241

Query: 4717 KAPKISMPDIDLNLKGPKVK---GDVDVTLPKVEGDLKGPEADIKGPKV--DINTPDVDV 4771
            K P+I +    L+LKGPK+     DV+V+ P +E D++ P A + G ++  D++  D DV
Sbjct: 3242 KGPQIDIKGPKLDLKGPKMDVTAPDVEVSQPSMEVDVEAPGAKLDGARLEGDLSLADKDV 3301

Query: 4772 HGPDWHLKMPKVKMPKF--SMPGFKGEGPDVDVSLPKADIDVSGP--------------- 4814
               D   KMPK KMP +  S PG K     VDVS PKA+ DVS P               
Sbjct: 3302 TAKDSKFKMPKFKMPSYRASAPG-KSIQASVDVSAPKAEADVSLPSMQGDLKTTDLSIQL 3360

Query: 4815 ----------KVDVDIPD------VNIEGPDAKLKGPKFKMPEINIKAPKISIPDVDLDL 4858
                      +VDV +P+        ++G   K++ P FKMP++++K+P++ I    LDL
Sbjct: 3361 PSVDLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVEMPSFKMPKVDLKSPQVDIKGPKLDL 3420

Query: 4859 KGPKVK---GDFDVSVPKVEGTLKGPEVDLKGPRL---------DFEGPDAKLSGPSLKM 4906
            K PK +    D +VS+P VE  ++ P   L G RL         D    D+K   P  KM
Sbjct: 3421 KVPKAEVTVPDVEVSLPSVEVDVQAPRAKLDGARLEGDLSLAEKDVTAKDSKFKMPKFKM 3480

Query: 4907 PS-------------LEISAPKVTA--------------------PDVDLHLKAPKIG-- 4931
            PS             L++SAPKV A                    P  DL ++A ++   
Sbjct: 3481 PSFGVSAPGRSIEASLDVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAVQVDVE 3540

Query: 4932 -FSGPKLEGGEVDLKGPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKFGFGAKSPKAD 4990
               GP  EG  +    PKVE PSL     +P ++++GP + +   K PK     K PKA+
Sbjct: 3541 LLEGPVPEGAGLKGHLPKVEMPSLK----TPKVDLKGPQIDV---KGPKLDL--KGPKAE 3591

Query: 4991 IKSPSLDVTVPEAELNLETP-----------EISVGGK---GKKSKFKMPKIHMSGPKI- 5035
            ++ P ++V++P  E++++ P           ++S+  K    K SKFKMPK  M   ++ 
Sbjct: 3592 VRVPDVEVSLPSVEVDVQAPKAKLDAGRLEGDLSLADKDVTAKDSKFKMPKFKMPSFRVS 3651

Query: 5036 ---KAKKQGFDLNVPGGEIDASLKAPD-----VDVNIAGPDAALKV-----DVKSPKTKK 5082
               K+ +   D++ P  E D SL +        D++I  P A LKV     DVK P+ + 
Sbjct: 3652 APGKSMEASVDVSAPKVEADVSLPSMQGDLKTTDLSIQPPSADLKVQAGQMDVKLPEGQV 3711

Query: 5083 TMFG--KMYFPDVEFDIKSPKFKAEAPLPSPKLEGELQAPDLELSLPAIHVEG--LDIKA 5138
                  K + P VE             +PS K+      P ++L  P + ++G  LD+K 
Sbjct: 3712 PEGAGLKEHLPKVE-------------MPSLKM------PKVDLKGPQVDIKGPKLDLKV 3752

Query: 5139 KAPKVKMPDVDISVPKIEGDLKGPK-------VQANLGAPDINIEGLDAKVKTP-----S 5186
               +V  PDV++S+P +E D++ P+       ++ +L   D ++   D+K K P     S
Sbjct: 3753 SKAEVTAPDVEVSLPSVEVDVQAPRAKLDSAQLEGDLSLADKDVTAKDSKFKMPKFKMPS 3812

Query: 5187 FGISAPQVSIPDVNVNLKGPKIKGDVPSVGLEGP-------------------------- 5220
            FG+SAP  SI + +V++  PK++ DV    ++G                           
Sbjct: 3813 FGVSAPGKSI-EASVHVSAPKVEADVSLPSMQGDLKTTDLSIQPHSADLTVQARQVDMKL 3871

Query: 5221 -------DVDLQGPEAKIKFPKFSMPKIGIPG--------------VKMEGGGAEVHAQL 5259
                   +  L+G   K++ P F MPK+ + G               K+E    +V   L
Sbjct: 3872 LEGHVPEEAGLKGHLPKVQMPSFKMPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSL 3931

Query: 5260 PSLEGDLRGPDVKLEG----------------PDVSLKGPGVDLPSVNLSMP-------- 5295
            PS+E D+  P  KL+G                 D   K P   +PS  +S P        
Sbjct: 3932 PSVEVDVEAPGAKLDGARLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGKSMEASV 3991

Query: 5296 KVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLSGVGGKMQV--------GGDGVK- 5346
             V+ P ++ ++  PS++GDL A+   + V  P  +L    G++ V         G  +K 
Sbjct: 3992 DVTAPKVEADVSLPSMQGDLKAT--DLSVQPPSADLEVQAGQVDVKLPEGPVPEGASLKG 4049

Query: 5347 -VPGIDATT----KLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLE------ 5395
             +P +   +    K+++  P + ++GP L        D+K PK  V APD+ +       
Sbjct: 4050 HLPKVQMPSFKMPKVDLKGPQIDVKGPKL--------DLKGPKAEVTAPDVKMSLSSMEV 4101

Query: 5396 --------------------------ASEGSIKLPKMKLPQFGISTPGSDL-------HV 5422
                                      A +   K+PK K+P FG+S PG  +        +
Sbjct: 4102 DVQAPRAKLDGVQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSMEASVDVSEL 4161

Query: 5423 NAKG----PQVSGELKGPGVDVNLKGP----RISAPNVDFNL-EGPKVKGSLGATGE--- 5470
             AK     P + G+LK    D++++ P     + A  VD  L EGP  KG+ G  G    
Sbjct: 4162 KAKADVSLPSMQGDLK--TTDLSIQSPSADLEVQAGQVDVKLPEGPLPKGA-GLKGHLPK 4218

Query: 5471 -----IKGPTVGGGLPGIGVQGLEGNLQMP--GIKSSGCDVNLPG--VNVKLPTGQISGP 5521
                 +K P V    P + V+G + +L+ P   + +   +V+LP   V+V+ P  ++   
Sbjct: 4219 VQMPCLKMPKVALKGPQVDVKGPKLDLKGPKADVMTPVVEVSLPSMEVDVEAPGAKLDSV 4278

Query: 5522 EIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDI 5581
             ++G L  ++      A D   K P F M S    FG++  G  I+   DVS      D+
Sbjct: 4279 RLEGDLSLADKDM--TAKDSKFKMPKFKMPS----FGVSAPGKSIEASLDVSALKVEADV 4332

Query: 5582 SLGE-------GHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSG------------P 5622
            SL          HLS++    + +       + L       G    G            P
Sbjct: 4333 SLPSMQGDLKTTHLSIQPPSADLEVQAGQEDVKLPEGPVHEGAGLKGHLPKLQMPSFKVP 4392

Query: 5623 KVEGGVKGGQIGLQAPGLSVSGPQGHLESGSGKVTFP----------------------- 5659
            KV+  +KG QI +  P L + GP+  + S +  V+ P                       
Sbjct: 4393 KVD--LKGPQIDVNVPKLDLKGPKVEVTSPNLDVSLPSMEVDIQAPGAKLDSTRLEGDLS 4450

Query: 5660 -----------KMKIPKFTFSGRELVGR----EMGVDVHFPKAEAS-------------- 5690
                       K K+PKF      ++      E+ VDV  PK EA               
Sbjct: 4451 LADKDVTAKDSKFKMPKFKMPSFGMLSPGKSIEVSVDVSAPKMEADMSIPSMQGDLKTTD 4510

Query: 5691 --IQAGAGDGEWEESEVKLK---------------KSKIKMPKFNFSKPKGKGGVTGSPE 5733
              IQA + D E +  +V LK                 K++MP F   K   KG     P+
Sbjct: 4511 LRIQAPSADLEVQAGQVDLKLPEGHMPEVAGLKGHLPKVEMPSFKMPKVDLKG-----PQ 4565

Query: 5734 ASISGSKGDLKSSKA---------SLGSLEGEAEAEASSPKGKFSLFKSKKPRHRSNSFS 5784
              + G K DLK  KA         SL S+E + +A  S   G   L       H   +  
Sbjct: 4566 VDVKGPKLDLKGPKAEVMAPDVEVSLPSVETDVQAPGSMLDGA-RLEGDLSLAHEDVAGK 4624

Query: 5785 DEREFSGPSTPTGTLEFEGGEVSLEGGKVKG 5815
            D + F GP   T   E+   +VS+   +++G
Sbjct: 4625 DSK-FQGPKLSTSGFEWSSKKVSMSSSEIEG 4654



 Score = 1107 bits (2863), Expect = 0.0
 Identities = 986/3392 (29%), Positives = 1546/3392 (45%), Gaps = 750/3392 (22%)

Query: 3064 DVNIEGPEGKLKGPKFKMPEMNIKAPKISMP-------DIDLNLKGP------------- 3103
            D   E  EG+++ PKFK+P +     K +         D +   +G              
Sbjct: 570  DKGREDTEGQIRMPKFKIPSLGWSPSKHTKTGREKATEDTEQGREGEATATADRREQRRT 629

Query: 3104 ----KVKGDMDVSLPKVEGDMKVPDV-DIKGPKVDINAPDVDVQGPDWHLKMPKIKMPKI 3158
                K K D D     +    K+  + D K  K +    + +V   D   KMPK KMP  
Sbjct: 630  EEGLKDKEDSD----SMTNTTKIQLIHDEKRLKKEQILTEKEVATKDSKFKMPKFKMPLF 685

Query: 3159 --SMPGFKGEGPEVDVNLPKADLDVS--GPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNI 3214
              S PG K     VDV+ PK + DVS    + D+   D++++ P A L+    +  ++++
Sbjct: 686  GASAPG-KSMEASVDVSAPKVEADVSLLSMQGDLKTTDLSVQTPSADLE---VQDGQVDV 741

Query: 3215 KAPKISMPDLDLNLKG--PKMKGEVDVSLANVEGDLKGPALDIKGPKIDVDAPDI----- 3267
            K P+  +P+   +LKG  PK++     SL   + DLKGP LD+KGPK +V APD+     
Sbjct: 742  KLPEGPLPE-GASLKGHLPKVQRP---SLKMPKVDLKGPKLDLKGPKAEVTAPDVKMSLS 797

Query: 3268 ----DIHGPDAKLKGPKLK-----------MPDMHVNMPKISMPEIDLNLKGSKLKGDVD 3312
                D+  P AKL G +L+             D    MPK  MP   ++  G  ++  VD
Sbjct: 798  SMEVDVQAPRAKLDGARLEGDLSLADKEVTAKDSKFKMPKFKMPSFGVSAPGKSMEDSVD 857

Query: 3313 VSGPKLEGDIKAPSL--DIKGPEVDVSGPKLNIEGKSKKSRFKLPKFNF---SGSKVQTP 3367
            VS PK+E D+   S+  D+K  ++ +  P  ++E ++ +   KLP+      +G KV  P
Sbjct: 858  VSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGPKVHLP 917

Query: 3368 EVDVKG-KKPDIDITGPKVDINAPDVEVQGKVKGSKFKMPFLSISSP--KVSMPDVELNL 3424
            +V++   K P +D+ GP++D+  P ++++G         P   +++P  +VS+P +E+++
Sbjct: 918  KVEMPSFKMPKVDLKGPQIDVKGPKLDLKG---------PKAEVTAPDGEVSLPSMEVDV 968

Query: 3425 KSPKVKGDLDIAGPNLEGDFKGPKVDIKAPEVNLNAPDVDVHGPDWNLKMPKMKMPKFSV 3484
            ++ K K D    G  LEGD              L+  D DV   D   KMPK KMP F V
Sbjct: 969  QAQKAKLD----GAWLEGD--------------LSLADKDVTAKDSKFKMPKFKMPSFGV 1010

Query: 3485 SG--------LKAEGPDVAVDLP----KGDINIEGPSMNIEGPDLNVEG----------- 3521
            S         +    P V  DL     +GD+     S+     DL V+            
Sbjct: 1011 SAPGKSIKALVDVSAPKVEADLSLPSMQGDLKTTDLSIQPASTDLKVQADQVDVKLPEGH 1070

Query: 3522 -PEG-GLKG-------PKFKMPDMNIKAPKISMPDIDLNLKGPKVK---GDVDISLPKLE 3569
             PEG GLKG       P FKMP + +K P++ +    L+LK PK +    DV++SLP +E
Sbjct: 1071 LPEGAGLKGHLPKVEMPSFKMPKVALKGPQVDVKGPKLDLKSPKAEVTAPDVEVSLPSVE 1130

Query: 3570 GDLKGPEVDIKGPKVD--INAPDVDVHGPDWHLKMPKVKMPKF--SMPGFKGEGPEVDVT 3625
             D++ P   +   +++  ++  D DV   D   KMPK KMP F  S PG K     VDV+
Sbjct: 1131 VDVEAPGAKLDSARLEGELSLADKDVTAKDSRFKMPKFKMPSFGASAPG-KSIEASVDVS 1189

Query: 3626 LPKADIDISGPNV--DVDVPDVNIEGPDA-----------------------------KL 3654
             PK + D+S P++  D+   D++I+ P A                             K+
Sbjct: 1190 APKVEADVSLPSMQGDLKTTDLSIQPPSADLEVHAGQVDVKLLEGHVPEGAGFKGHLPKV 1249

Query: 3655 KGPKFKMPEMNIKAPKISMPDFDLNLKGPKMK---GDVVVSLPKVEGDLKGPEVDIKGPK 3711
            + P  KMP++++K P++ +    L+LKG K +    +V VSLP VE D++ P   + G +
Sbjct: 1250 QMPSLKMPKVDLKGPQVEVRGPKLDLKGHKAEVTAHEVAVSLPSVEVDMQAPGAKLDGAQ 1309

Query: 3712 VDIDTP--DINIEGSEGKFKGPKFKIPEMHLKAPKISMPDIDLNLKGPKVKGDVDVSLPK 3769
            +D D    D ++   + KFK PKFK+P   + AP  S+ +  ++L  PKV  + D+SLP 
Sbjct: 1310 LDGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSI-EASVDLSAPKV--EADMSLPS 1366

Query: 3770 MEGDLKGPEVDIKGPKVDIN--APDVDVQGPDWHLK--------MPKVKMPKFSMPGFKG 3819
            M+GDLK  ++ I+ P  D+   A  +DV+ P+  +         +PK++MP F +P    
Sbjct: 1367 MQGDLKTTDLSIQPPSTDLELQAGQLDVKLPEGPVPEGAGLKGHLPKLQMPSFKVPKVDL 1426

Query: 3820 EGPDVDVNLPKADL-----DVSGPKVDIDVP--DVNIEGPEGKLKG-------------- 3858
            +GP++D+  PK DL     +V+ P V++ +P  +V++E P  KL G              
Sbjct: 1427 KGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGGRLEEDMSLADKDL 1486

Query: 3859 ---------PKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMQVPDLDI 3909
                     PKFKMP   + AP  S+ +  +++  PKV+ D  VSLP ++GD++  DL I
Sbjct: 1487 TTKDSKFKMPKFKMPSFGVSAPGKSI-EASVDVSAPKVEAD--VSLPSMQGDLKATDLSI 1543

Query: 3910 KGPKVD--INAPDVDVRGPDWHLK--------MPKIKMPKISMPGFKGEGPEVDVNLPKA 3959
            + P  D  + A  VDV+ P+  +         +PK++MP   MP    +GP++DV  PK 
Sbjct: 1544 QPPSADLEVQAGQVDVKLPEGPVSEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPK- 1602

Query: 3960 DLDVSGPKVDVDVPDV---------NIEGPDAKLKG-----------------------P 3987
             LD+ GPKV+V  PDV         +++ P AKL G                       P
Sbjct: 1603 -LDLKGPKVEVTAPDVKMSLSSMEVDVQAPRAKLDGAQLEGDLSLADKAVTAKDSKFKMP 1661

Query: 3988 KFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKVDID-- 4045
            KFKMP   + AP  S+ +  + +  PKV  + DVSLP M+GDLK  ++ I+ P  D++  
Sbjct: 1662 KFKMPSFGVSAPGKSI-EASVDVSEPKV--EADVSLPSMQGDLKTTDLSIQSPSADLEVQ 1718

Query: 4046 APDVDVHGPDWHLK--------MPKVKMPKFSMPGFKGEGPEVDVNLPKADIDVSGPKVD 4097
            A  V+V  P+  L         +PKV+MP   MP    +GP++DV  PK  +D+ GPK +
Sbjct: 1719 AGQVNVKLPEGPLPEGAGFKGHLPKVQMPSLKMPKVALKGPQMDVKGPK--LDLKGPKAE 1776

Query: 4098 IDTPDIDIHGP--------------------------------EGKLKGPKFKMPDLHLK 4125
            +  PD+++  P                                + K K PKFKMP   + 
Sbjct: 1777 VMAPDVEVSLPSVEVDVEAPGAKLDSVRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVS 1836

Query: 4126 APKISMPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDVP--DVDVQGPD 4183
            AP  S+ E  +++  PK+  + +VSLP ++GDLK  ++ I  P  D+ V    VD++ P+
Sbjct: 1837 APGKSI-EASVDVSAPKV--EAEVSLPSMQGDLKTTDLCIPLPSADLVVQAGQVDMKLPE 1893

Query: 4184 WHLK--------MPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEG 4235
              +         +PKV MP F MP    +GP  DV    A LD+ GPK ++  PDV +  
Sbjct: 1894 GQVPEGAGLKGHLPKVDMPSFKMPKVDLKGPQTDVK--GAKLDLKGPKAEVTAPDVEVSL 1951

Query: 4236 P--------------------------------DAKLKGPKFKMPEMNIKAPKISMPDFD 4263
            P                                D+K K PKFKMP   + AP  S+ +  
Sbjct: 1952 PSMEVDVQAQKAKLDGARLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGRSI-EAS 2010

Query: 4264 LHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVD--IDAPDVDVHGPDWHLK------ 4315
            + +  PKV  + DVSLP ++GDLK  ++ I+ P  D  +    VDV  P+ H+       
Sbjct: 2011 VDVPAPKV--EADVSLPSMQGDLKTTDLSIQPPSADLKVQTGQVDVKLPEGHVPEGAGLK 2068

Query: 4316 --MPKVKMPKFSMPGFKGEGPDVDVTLPKADIEISGPKVDIDAPDVSIEGP--------- 4364
              +PKV+MP   MP    +GP VD+  PK D++   PKV++  PDV +  P         
Sbjct: 2069 GHLPKVEMPSLKMPKVDLKGPQVDIKGPKLDLK--DPKVEMRVPDVEVSLPSMEVDVQAP 2126

Query: 4365 -----------------------DAKLKGPKFKMPEMNIKAPKISMPDIDFNLKGPKVKG 4401
                                   D+K K PKFKMP   + AP  S+ +   ++  PKV  
Sbjct: 2127 RAKLDSAHLQGDLTLANKDLTTKDSKFKMPKFKMPSFGVSAPGKSI-EASVDVSPPKV-- 2183

Query: 4402 DVDVSLPKVEGDLKGPEIDIKGPSLDIDTP---------------DVNIEGPEGKLKGPK 4446
            + D+SLP ++GDLK  ++ I+  S D+                  +V ++G   KL+ P 
Sbjct: 2184 EADMSLPSMQGDLKTTDLSIQPLSADVKVQAGQVDVKLLEGPVPEEVGLKGHLPKLQMPS 2243

Query: 4447 FKMPEMNIKAPKISMPDFDLHLKGPKVK---GDVDVSLPKVESDLKGPEVDIEGP--EGK 4501
            FK+P++++K P+I +    L LK PKV+    DV+VSLP VE D+K P   ++G   EG 
Sbjct: 2244 FKVPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVKAPGAKLDGARLEGD 2303

Query: 4502 L---------KGPKFKMPDVHFKSPQISM--SDIDLNLKGPKIKGDMDISVPKLEGDLKG 4550
            +         K  KFKMP     S  +S     I+ +     +K + D+S+P ++GDLK 
Sbjct: 2304 MSLADKDVTAKDSKFKMPKFKMLSFGVSALGKSIEASADVSALKVEADVSLPSMQGDLKT 2363

Query: 4551 PKVDVKGPKVGIDTP--DIDIHGPEG-------------KLKGPKFKMPDLHLKAPKISM 4595
              + V+ P   ++     +D+  PEG             KL+ P FKMP + LK P+I +
Sbjct: 2364 TDLSVQPPSADLEVQAGQVDVKLPEGPVPEGAGLKGHLPKLQMPSFKMPKVDLKGPQIDV 2423

Query: 4596 PEVDLNLKGPK---VKGDMDISLPKVEGDLKGP--EVDIRDPKVDIDVPDVDVQGPDWHL 4650
                L+LKGPK   +  D+++S P VE D++ P  ++D    + D+ V D DV   D   
Sbjct: 2424 KGPKLDLKGPKTDVMAPDVEVSQPSVEVDVEAPGAKLDGAWLEGDLSVADKDVTTKDSRF 2483

Query: 4651 KMPKVKMPKF---------------SMPGFKGEGP-----------DVDVNLPKADIDVS 4684
            K+PK KMP F               S P  + +G            D+ +  P AD++V 
Sbjct: 2484 KIPKFKMPSFGVSAPGKSIEASVDVSAPKVEADGSLSSMQGDLKATDLSIQPPSADLEVQ 2543

Query: 4685 GPKVDVDVPD------VNIEGPDAKLKGPKFKMPEMSIKAPKISMPDIDLNLKGPKVK-- 4736
              +VDV +P+        ++G   K++ P FKMPEM +K P++ +    L+LKGPK +  
Sbjct: 2544 AGQVDVKLPEGPVPEGAGLKGHLPKVQMPSFKMPEMDLKGPQLDVKGPKLDLKGPKAEVT 2603

Query: 4737 -GDVDVTLPKVEGDLKGPEADIKGPKV--DINTPDVDVHGPDWHLKMPKVKMPKF--SMP 4791
              DV+++L  +E D++ P A + G ++  D++  D  V   D   KMPK KMP F  S P
Sbjct: 2604 APDVEMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGVTAKDSKFKMPKFKMPSFRVSAP 2663

Query: 4792 GFKGEGPDVDVSLPKADIDVSGPKVDVDIP--DVNIEGPDAKLKGPKFKMPEINIKAPKI 4849
            G   E   VDVS  K + D+S P +  D+   D++I+ P A+L+    +  ++++K P+ 
Sbjct: 2664 GESIEAL-VDVSELKVEADMSLPSMQGDLKTTDISIQPPSAQLE---VQAGQVDVKLPEG 2719

Query: 4850 SIPDVDLDLKGPKVKGDFDVSVPKVE-GTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPS 4908
             +P+      G  +KG     +PK++  + K PEVDLKGP++D +GP+  L GP  +   
Sbjct: 2720 HVPE------GAGLKGH----LPKLQMPSFKMPEVDLKGPQIDVKGPNVDLKGPKAE--- 2766

Query: 4909 LEISAPKVTAPDVDLHLKAPKIGFSGPKLEGGEVDLKGPKVEAPSLDVHMDSPDINIEGP 4968
                   VTAPDV + L + ++    P+ +     L G ++E    D+ +    +  +  
Sbjct: 2767 -------VTAPDVKMSLSSMEVDVQAPRAK-----LDGARLEG---DLSLADKGMTAKDS 2811

Query: 4969 DVKIPKFKKPKFGFGAK----------------------SPKADIKSPSLDVTVPEAELN 5006
              K+PKFK P FG  A                       S + D+K+  + +  P A+L 
Sbjct: 2812 KFKMPKFKMPSFGVSAPGKSIEASVDVSELKVEADGSFPSMQGDLKTTDIRIQPPSAQLE 2871

Query: 5007 LETPEISV-----------GGKGKKSK-----FKMPKIHMSGPKIKAKKQGFDLNVPGGE 5050
            ++  ++ V           G KG   K     FKMPK+ + GP+I  K    DL  P  E
Sbjct: 2872 VQAGQVDVKLPEGHVPEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAE 2931

Query: 5051 I---DASLKAPDVDVNIAGPDAALK------------VDV-------KSPKTKKTMFGKM 5088
            +   D  +  P V+V++  P A L              DV       K PK K   FG +
Sbjct: 2932 VTAPDVEVSLPSVEVDVEAPRAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSFG-V 2990

Query: 5089 YFP----DVEFDIKSPKFKAEAPLPS--------------PKLEGELQAPDLELSLPAIH 5130
              P    +V  D+ +PK +AE  LPS              P  + E+QA  ++L LP  H
Sbjct: 2991 SAPGKSIEVSVDVSAPKVEAEVSLPSMQGDLKTTDISIEPPSAQLEVQAGQVDLKLPEGH 3050

Query: 5131 V-EGLDIKAKAPKVKMPDVDISVPKIEGDLKGPKVQANLGAPDINIEGLDAKVKTPSFGI 5189
            V EG  +K   PK++MP     +PK+  D KGP++      P ++++G    V  P   +
Sbjct: 3051 VPEGAGLKGHLPKLQMPS--FKMPKV--DRKGPQIDVK--GPKLDLKGPKTDVTAPDVEV 3104

Query: 5190 SAP--QVSIPDVNVNLKGPKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGI--PG 5245
            S P  +V +      L G +++GD     L   D D+   ++K K PKF MP  G+  PG
Sbjct: 3105 SQPGMEVDVEAPGAKLDGARLEGD-----LSLADKDVTAKDSKFKMPKFKMPSFGVSAPG 3159

Query: 5246 VKME------GGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPK--- 5296
              +E          E    LPS++GDL+  D+ +E P   L+   V    V++ +P+   
Sbjct: 3160 KSIEVLVDVSAPKVEADLSLPSMQGDLKNTDISIEPPSAQLE---VQAGQVDVKLPEGHV 3216

Query: 5297 VSGPDLDLNL---KGPSLK-GDLDASVPSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDA 5352
            + G  L  +L   + PS K   +D   P + +  P L+L G   KM V    V+V     
Sbjct: 3217 LEGAGLKGHLPKLQMPSFKMPKVDRKGPQIDIKGPKLDLKGP--KMDVTAPDVEVS--QP 3272

Query: 5353 TTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFG 5412
            + +++V AP   L G  L+GDL+++             D  + A +   K+PK K+P + 
Sbjct: 3273 SMEVDVEAPGAKLDGARLEGDLSLA-------------DKDVTAKDSKFKMPKFKMPSYR 3319

Query: 5413 ISTPGSDLH--VNAKGPQVSGELKGPGVDVNLKGPRISA--PNVDFNLEGPKVKGSLGAT 5468
             S PG  +   V+   P+   ++  P +  +LK   +S   P+VD  ++  +V   L   
Sbjct: 3320 ASAPGKSIQASVDVSAPKAEADVSLPSMQGDLKTTDLSIQLPSVDLEVQAGQVDVKLPEG 3379

Query: 5469 GEIKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLK 5528
               +G  + G LP + +   +  +    +KS   D+  P +++K+P  +++ P+++  L 
Sbjct: 3380 HVPEGAGLKGHLPKVEMPSFK--MPKVDLKSPQVDIKGPKLDLKVPKAEVTVPDVEVSLP 3437

Query: 5529 GSEVGFHG---------------------AAPDISVKGPAFNMASPESDFGINLKGPKIK 5567
              EV                          A D   K P F M S    FG++  G  I+
Sbjct: 3438 SVEVDVQAPRAKLDGARLEGDLSLAEKDVTAKDSKFKMPKFKMPS----FGVSAPGRSIE 3493

Query: 5568 GGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVS---SALNLDTSKFAG------GLH 5618
               DVS      D+SL      +K +    + P       A+ +D     G      GL 
Sbjct: 3494 ASLDVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAVQVDVELLEGPVPEGAGLK 3553

Query: 5619 FSGPKVE-GGVKGGQIGLQAPGLSVSGPQGHLESGSGKVTFPKMKIPKFTFSGRELVGRE 5677
               PKVE   +K  ++ L+ P + V GP+  L+    +V  P +++              
Sbjct: 3554 GHLPKVEMPSLKTPKVDLKGPQIDVKGPKLDLKGPKAEVRVPDVEVSL----------PS 3603

Query: 5678 MGVDVHFPKAEASIQAGAGDGEWEESEVKLKKSKIKMPKFNFSKPKGKGGVTGSPEASIS 5737
            + VDV  PKA+       GD    + +V  K SK KMPKF              P   +S
Sbjct: 3604 VEVDVQAPKAKLDAGRLEGDLSLADKDVTAKDSKFKMPKFKM------------PSFRVS 3651

Query: 5738 GSKGDLKSSKASLGSLEGEAEAEASSPKGKFSLFKSKKPRHRSNSFSDEREFSGPSTPTG 5797
                  KS +AS+     + EA+ S P  +  L        ++   S +        P+ 
Sbjct: 3652 APG---KSMEASVDVSAPKVEADVSLPSMQGDL--------KTTDLSIQ-------PPSA 3693

Query: 5798 TLEFEGGEVSLEGGKVKGKHGKLKFGTFGGLGSKSKGHYEVTGSDDETGKLQGSGVSLAS 5857
             L+ + G++      VK   G++  G   GL  +     E+         L+G  V +  
Sbjct: 3694 DLKVQAGQMD-----VKLPEGQVPEGA--GL-KEHLPKVEMPSLKMPKVDLKGPQVDIKG 3745

Query: 5858 KKSRLSSSSSNDSGNKVGIQLPEVELSVSTKK 5889
             K  L  S +  +   V + LP VE+ V   +
Sbjct: 3746 PKLDLKVSKAEVTAPDVEVSLPSVEVDVQAPR 3777



 Score = 34.7 bits (78), Expect = 2.9
 Identities = 66/281 (23%), Positives = 104/281 (37%), Gaps = 46/281 (16%)

Query: 5623 KVEGGVKGGQIGLQAPGLSVSGPQGHLESGSGKVTFPKMKIPKFTFSGRE--LVGREMGV 5680
            + +G    G+ GLQ   ++    +G  E   G++  PK KIP   +S  +    GRE   
Sbjct: 548  EAQGDEGDGEEGLQRTRITEEQDKGR-EDTEGQIRMPKFKIPSLGWSPSKHTKTGREKAT 606

Query: 5681 DVHFPKAEASIQAGAGDGEWEESEVKLKKSK--------IKMPKFNFSKPKGKGGVTGSP 5732
            +      E    A A   E   +E  LK  +         K+   +  K   K  +    
Sbjct: 607  EDTEQGREGEATATADRREQRRTEEGLKDKEDSDSMTNTTKIQLIHDEKRLKKEQILTEK 666

Query: 5733 EASISGSKGDLKSSK-----ASLGSLEGEAEAEASSPKGKFSL-FKSKKPRHRSNSFSDE 5786
            E +   SK  +   K     AS      EA  + S+PK +  +   S +   ++   S +
Sbjct: 667  EVATKDSKFKMPKFKMPLFGASAPGKSMEASVDVSAPKVEADVSLLSMQGDLKTTDLSVQ 726

Query: 5787 REFSGPSTPTGTLEFEGGEVSLEGGKVKGKHGKLKFGTFGGLGSKSKGHYEVTGSDDETG 5846
                   TP+  LE + G+V      VK   G L        G+  KGH           
Sbjct: 727  -------TPSADLEVQDGQVD-----VKLPEGPLP------EGASLKGHLP--------- 759

Query: 5847 KLQGSGVSLASKKSRLSSSSSNDSGNKVGIQLPEVELSVST 5887
            K+Q    SL   K  L     +  G K  +  P+V++S+S+
Sbjct: 760  KVQRP--SLKMPKVDLKGPKLDLKGPKAEVTAPDVKMSLSS 798


>gi|116686120 periaxin isoform 2 [Homo sapiens]
          Length = 1461

 Score =  266 bits (679), Expect = 6e-70
 Identities = 399/1556 (25%), Positives = 695/1556 (44%), Gaps = 351/1556 (22%)

Query: 2462 LKGPKIK-GDVDV-SVPEVEGKLEVPDMNIRGPKVDVNAPDVQAPDWHLKMPKMKMPKFS 2519
            +KGP+ K   +++ S+  V+ K  VP     G   D+   DV+             PKFS
Sbjct: 117  IKGPRAKVAKLNIQSLSPVKKKKMVP--GALGVPADLAPVDVE----------FSFPKFS 164

Query: 2520 M--PGFKAEGPEVDVNLPKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAP 2577
                G KAE  +  V    A   +  P++ +   +V  E    +L        +  ++A 
Sbjct: 165  RLRRGLKAEAVKGPVPAAPARRRLQLPRLRVR--EVAEEAQAARLAAAAPPPRKAKVEAE 222

Query: 2578 KISMPDF---DLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKG------PKVDINAP-DV 2627
              +   F    + L GP++ G  +V +P+V      P  +  G      P + + AP   
Sbjct: 223  VAAGARFTAPQVELVGPRLPG-AEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPP 281

Query: 2628 GVQGPDWHLKMPKVKMPKF-SMPGFKG----EGPDGDVKLPKADIDVSGPKVDIEGPDVN 2682
             V+ P   +++P+V++P   S+P        E  +G V +    +DV+ P V   G D+ 
Sbjct: 282  AVEAPAVGIQVPQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTV---GVDLA 338

Query: 2683 IEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVD 2742
            + G E + +G   + PE+ +K P++S P       G + K   +  + KV      PE  
Sbjct: 339  LPGAEVEARG---EAPEVALKMPRLSFPRF-----GARAKEVAEAKVAKVS-----PEAR 385

Query: 2743 IKGPKVDIDAPDVDVHGPDWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKV 2802
            +KGP++ +    + +  P      P++   K+ +P  K         +P   I VSGP+V
Sbjct: 386  VKGPRLRMPTFGLSLLEP--RPAAPEVVESKLKLPTIK---------MPSLGIGVSGPEV 434

Query: 2803 DVECPDVNIEGPEGKW-KSPKFKMPEM-HFKTPKISMPDIDLNLTGPKIKGDVDVTGPKV 2860
             V       +GPE K  K+P+ K+P++     P++ +P+++L    PK+    ++  PKV
Sbjct: 435  KVP------KGPEVKLPKAPEVKLPKVPEAALPEVRLPEVEL----PKVS---EMKLPKV 481

Query: 2861 EG----DLKGPEVDL------KGPKV-DIDVPDVNVQGPDWHLKMPKMKMPKFSMPGFKA 2909
                  +++ PEV+L      K PKV ++ VP+V +      LK+ +MK+PK      + 
Sbjct: 482  PEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVQL-LKVSEMKLPKVP----EM 536

Query: 2910 EGPEV---DVNLPKADVDVSGPKV-DVEGPDVNIEGPEGKL-KGPKFKMPEMNIKAPKIP 2964
              PEV   +V LPK   ++  P+V +V  P+V +  PE +L K P+ K+PEM  K PK+P
Sbjct: 537  AVPEVRLPEVQLPKVS-EMKLPEVSEVAVPEVRL--PEVQLPKVPEMKVPEM--KLPKVP 591

Query: 2965 MPDFDLHLKGPKVKGDVDISLPKVEGDLKGPEVDIRGPQVDIDVPDVGVQGPDWHLKMPK 3024
                   +K P++K   ++ LPKV      PE+ +     D+ +P+V +       K+P+
Sbjct: 592  ------EMKLPEMKLP-EVQLPKV------PEMAVP----DVHLPEVQLP------KVPE 628

Query: 3025 VKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPEGKL-KGPKFKMPE 3083
            +K+P+  +P         +V LPK          ++ VPDV++  PE +L K P+ K+P+
Sbjct: 629  MKLPEMKLP---------EVKLPKVP--------EMAVPDVHL--PEVQLPKVPEMKLPK 669

Query: 3084 M-NIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMKVPDVDIKGPKVDINAPDV-DV 3141
            M  +  P++ +P++ L    PKV    ++ LPKV  +M VPDV +     ++  P V ++
Sbjct: 670  MPEMAVPEVRLPEVQL----PKVS---EMKLPKVP-EMAVPDVHLP----EVQLPKVCEM 717

Query: 3142 QGPDWHLKMPKIKMPKISMPGFKGEGPEVDVNLPKADLDVSGPKV-DVDVPDVNI-EGPD 3199
            + PD  +K+P+IK+PK+       E    DV+LP+  L    PKV ++ +P++ + + PD
Sbjct: 718  KVPD--MKLPEIKLPKVP------EMAVPDVHLPEVQL----PKVSEIRLPEMQVPKVPD 765

Query: 3200 AKL-KGPKFKMP---EMNIKAPKISMPD-LDLNLKGPKMKGEVDVSLANVEGDLKGP--- 3251
              L K P+ K+P   E+ +KA K    + ++   K PKM       L   E   +G    
Sbjct: 766  VHLPKAPEVKLPRAPEVQLKATKAEQAEGMEFGFKMPKMTMP---KLGRAESPSRGKPGE 822

Query: 3252 -ALDIKGPKIDVDAPDIDIHGPDAKLKGPKLKMPDMHVNMPKISMPEIDLNLKGSK-LKG 3309
               ++ G  + +     ++ G             + HV +P +++P ++L+L G+  L+G
Sbjct: 823  AGAEVSGKLVTLPCLQPEVDG-------------EAHVGVPSLTLPSVELDLPGALGLQG 869

Query: 3310 DVD---------VSGPKLEGDIK-----APSLDIKGPE---VDVSGPKLN-IEGKSK-KS 3350
             V          V GP++   ++      PS++I  P+   V++   +L  IE K K  S
Sbjct: 870  QVPAAKMGKGERVEGPEVAAGVREVGFRVPSVEIVTPQLPAVEIEEGRLEMIETKVKPSS 929

Query: 3351 RFKLPKFNFSGSKVQTPEVDVKGKKPDIDITG-----PKVDINAPDVEVQGKVKGSKFKM 3405
            +F LPKF  SG KV   E +  G+   + ++      PK  + A   E + K  G    +
Sbjct: 930  KFSLPKFGLSGPKVAKAEAEGAGRATKLKVSKFAISLPKARVGA---EAEAKGAGEAGLL 986

Query: 3406 PFLSISSPKVSMPDVELNLKSPKVKGDLDIAGPNLEGDFKGPKV----------DIKAPE 3455
            P L +S P++S+   + +L S KV    ++AG +L+  FKGP+           D +A E
Sbjct: 987  PALDLSIPQLSL---DAHLPSGKV----EVAGADLK--FKGPRFALPKFGVRGRDTEAAE 1037

Query: 3456 VNLNAPDVDVHGPDWN--LKMPKMKMPKFSVSGLKAEGPDVAVDLPKGDINIEGPSMNIE 3513
            +     +++  G  W+  +KMPK+KMP F ++                            
Sbjct: 1038 LVPGVAELEGKGWGWDGRVKMPKLKMPSFGLA---------------------------R 1070

Query: 3514 GPDLNVEGPEGGLKGPKFKMPDMNIKAPKISMPDIDLNLKGPKVKGDVDISLPKLEGDLK 3573
            G +  V+G      G K +   + +K P++ +  +    +G            + EG + 
Sbjct: 1071 GKEAEVQGDRAS-PGEKAESTAVQLKIPEVELVTLGAQEEG------------RAEGAVA 1117

Query: 3574 GPEVDIKGPKVDINAPDVDVHGPDWHLKMPK--VKMPKFSMPGFKGE----GPEVDVTLP 3627
               + + G KV   A  V   G D  L+MP   + +P+  + GF GE    G +   T+P
Sbjct: 1118 VSGMQLSGLKVS-TAGQVVTEGHDAGLRMPPLGISLPQVELTGF-GEAGTPGQQAQSTVP 1175

Query: 3628 KADIDISGPNVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP--DFDLNLKGPKM 3685
             A+         V VP V +  P A++ G +  + E   K P +++P  + D+ L     
Sbjct: 1176 SAE---GTAGYRVQVPQVTLSLPGAQVAGGELLVGEGVFKMPTVTVPQLELDVGLSREAQ 1232

Query: 3686 KGDVVVSLPKVEGDLKGPEVDIKGPKVDIDTPDINIEGSEGKFKGPKFKIPEMHLKAPKI 3745
             G+        EG L+     +K P +      +  EG+E +  G +        +   +
Sbjct: 1233 AGEAATG----EGGLR-----LKLPTLGA-RARVGGEGAEEQPPGAE--------RTFCL 1274

Query: 3746 SMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPEVDIKGPKVD-INAPDVDVQGPDWHLKM 3804
            S+PD++L+   P      +  + + EG+  G ++ ++ P+   + A +   +G     K 
Sbjct: 1275 SLPDVELS---PSGGNHAEYQVAEGEGE-AGHKLKVRLPRFGLVRAKEGAEEGE--KAKS 1328

Query: 3805 PKVKMPK--FSMPGF-KGEGPDVDVNLPKADLDVSG--------------PKVDIDVPDV 3847
            PK+++P+  FS      GEG        + + + SG              P+V +  P  
Sbjct: 1329 PKLRLPRVGFSQSEMVTGEGSPSPEEEEEEEEEGSGEGASGRRGRVRVRLPRVGLAAPSK 1388

Query: 3848 NIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLK-----GPKVKGDMDVSLPKV 3898
               G EG    PK  + E   K+PK   P + L+ K     G + +G + V LP V
Sbjct: 1389 ASRGQEGD-AAPKSPVRE---KSPKFRFPRVSLSPKARSGSGDQEEGGLRVRLPSV 1440



 Score =  248 bits (633), Expect = 1e-64
 Identities = 395/1534 (25%), Positives = 671/1534 (43%), Gaps = 350/1534 (22%)

Query: 800  KLKGPKFKMPEMNIKVPKISMPDVDLHLKGPNVKGEYDVTMPKVESEIKVPDVEL---KS 856
            ++KGP+ K+ ++NI+    S+  V      P   G        V +++   DVE    K 
Sbjct: 116  EIKGPRAKVAKLNIQ----SLSPVKKKKMVPGALG--------VPADLAPVDVEFSFPKF 163

Query: 857  AKMDIDVPDVEVQGP------DWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISG 910
            +++   +    V+GP         L++P++++ + +     A        L  A      
Sbjct: 164  SRLRRGLKAEAVKGPVPAAPARRRLQLPRLRVREVAEEAQAAR-------LAAAAPPPRK 216

Query: 911  PKVGVEVP-DVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGPKVKGEYDMTVP 969
             KV  EV        P+ +L GP+  +P   +  P++S P         +  G + + +P
Sbjct: 217  AKVEAEVAAGARFTAPQVELVGPR--LPGAEVGVPQVSAPKA---APSAEAAGGFALHLP 271

Query: 970  KLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKF-SMPSLKG----EGPEFDVNLSK 1024
             L      P   V AP V +Q       +P++++P   S+P+L      E  E  V++  
Sbjct: 272  TLGLGAPAPPA-VEAPAVGIQ-------VPQVELPALPSLPTLPTLPCLETREGAVSVVV 323

Query: 1025 ANVDISAPKVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKGPKMKGN 1084
              +D++AP V     DL+L G E + +G   + PE+  + P++S P       G + K  
Sbjct: 324  PTLDVAAPTVGV---DLALPGAEVEARG---EAPEVALKMPRLSFPRF-----GARAKEV 372

Query: 1085 VDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLKGEGP 1144
             +    K+      P+  ++GP+  ++ P      L+     P++   K  +P++K    
Sbjct: 373  AEAKVAKVS-----PEARVKGPR--LRMPTFGLSLLEPRPAAPEVVESKLKLPTIK---- 421

Query: 1145 EVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKL-KGPKFKMPEM-HFKTPKISMPDVDL 1202
                 +P   + VSGP+V +       +GPE KL K P+ K+P++     P++ +P+V+L
Sbjct: 422  -----MPSLGIGVSGPEVKVP------KGPEVKLPKAPEVKLPKVPEAALPEVRLPEVEL 470

Query: 1203 HLKGPKVKGDVDVSVPKVEGEMKVPDVEIKGPKMDIDAPDV-EVQGPDWHLKMPKMKMPK 1261
                PKV    ++ +PKV  EM VP+V +     +++ P V E++ P    K+P+M +P+
Sbjct: 471  ----PKVS---EMKLPKVP-EMAVPEVRLP----EVELPKVSEMKLP----KVPEMAVPE 514

Query: 1262 FSMPGFKGEGREVDVNLPKADIDVSGPKV-DVEVPDVSLEGPEGKL-KGPKFKMPEMHFK 1319
              +P         +V L K   ++  PKV ++ VP+V L  PE +L K  + K+PE+   
Sbjct: 515  VRLP---------EVQLLKVS-EMKLPKVPEMAVPEVRL--PEVQLPKVSEMKLPEVSEV 562

Query: 1320 A-PKISMPDVDLNLKGPKLKGDVDVSLPEVEGEMKVPDV---DIKGPKV-DISAPDVDVH 1374
            A P++ +P+V L  K P++K   ++ LP+V  EMK+P++   +++ PKV +++ PDV  H
Sbjct: 563  AVPEVRLPEVQLP-KVPEMKVP-EMKLPKVP-EMKLPEMKLPEVQLPKVPEMAVPDV--H 617

Query: 1375 GPDWHL-KMPKVKMPKFSMPGFKGEGPEVDVKLPKADVDVSGPKMDAEVPDVNIEGPDAK 1433
             P+  L K+P++K+P+  +P         +VKLPK       P+M   VPDV++  P+ +
Sbjct: 618  LPEVQLPKVPEMKLPEMKLP---------EVKLPKV------PEM--AVPDVHL--PEVQ 658

Query: 1434 L-KGPKFKMPEMSIKPQKISIPDVGLHLKGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKV 1492
            L K P+ K+P+M     ++++P+V L           +V +PKV         ++K PKV
Sbjct: 659  LPKVPEMKLPKMP----EMAVPEVRLP----------EVQLPKVS--------EMKLPKV 696

Query: 1493 DINAPDVEVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKV-DIDVP 1551
                P++ V  PD HL  P+V++PK        E    DM LP+  L    PKV ++ VP
Sbjct: 697  ----PEMAV--PDVHL--PEVQLPKVC------EMKVPDMKLPEIKL----PKVPEMAVP 738

Query: 1552 DVNLEAPEGKL-KGPKFKMPSMNIQTHKISMPDVGLNLKAPKLKTDVDVSLPKVEGDLKG 1610
            DV+L  PE +L K  + ++P M +      +PDV L  KAP++K      LP+       
Sbjct: 739  DVHL--PEVQLPKVSEIRLPEMQVP----KVPDVHLP-KAPEVK------LPRA------ 779

Query: 1611 PEIDVKAPKMDVNVGDIDIEGPEGKLKGPKFKMPEM-HFKAPKISMPDVDLHLKGPKVKG 1669
            PE+ +KA K +        EG E   K PK  MP++   ++P    P       G +V G
Sbjct: 780  PEVQLKATKAE------QAEGMEFGFKMPKMTMPKLGRAESPSRGKPGE----AGAEVSG 829

Query: 1670 DM---DVSVPKVEGEMKVPDVDIKGPKVDIDAPDVEVHDPDWHLKMPKMKMPKFSMPGFK 1726
             +       P+V+GE  V    +  P V++D P           ++P  KM K    G +
Sbjct: 830  KLVTLPCLQPEVDGEAHVGVPSLTLPSVELDLPGAL----GLQGQVPAAKMGK----GER 881

Query: 1727 AEGPEVDVNLPKADIDVSGPSVDTDAPDLD-IEGPEGKLK--------GSKFKMPKLNIK 1777
             EGPEV   + +    V  PSV+   P L  +E  EG+L+         SKF +PK  + 
Sbjct: 882  VEGPEVAAGVREVGFRV--PSVEIVTPQLPAVEIEEGRLEMIETKVKPSSKFSLPKFGLS 939

Query: 1778 APKVSMPDVDLNLKGPKLK-GEIDASVPELEGDLRGPQVDVKGPFVEAEVPDVDLECP-- 1834
             PKV+  + +   +  KLK  +   S+P+      G + + KG      +P +DL  P  
Sbjct: 940  GPKVAKAEAEGAGRATKLKVSKFAISLPKARV---GAEAEAKGAGEAGLLPALDLSIPQL 996

Query: 1835 ----------------DAKLKGPKFKMPEM----------------------------HF 1850
                            D K KGP+F +P+                               
Sbjct: 997  SLDAHLPSGKVEVAGADLKFKGPRFALPKFGVRGRDTEAAELVPGVAELEGKGWGWDGRV 1056

Query: 1851 KAPKISMPDVDLHLKGPKVKGDADVSVPKLEGDLTGPSVGVEVPDVELECPDAKLKGPK- 1909
            K PK+ MP   L  +G + +   D + P  + + T  +V +++P+VEL    A+ +G   
Sbjct: 1057 KMPKLKMPSFGL-ARGKEAEVQGDRASPGEKAEST--AVQLKIPEVELVTLGAQEEGRAE 1113

Query: 1910 --FKMPDMHFKAPKIS---------------MPDVDLHLKGPKVKGDVDVSVPKLEGDLT 1952
                +  M     K+S               MP + + L   ++ G  +   P  +   T
Sbjct: 1114 GAVAVSGMQLSGLKVSTAGQVVTEGHDAGLRMPPLGISLPQVELTGFGEAGTPGQQAQST 1173

Query: 1953 GPSVG------VEVPDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVKGD 2006
             PS        V+VP V L  P A++ G +  + E  FK P +++P ++L +   +    
Sbjct: 1174 VPSAEGTAGYRVQVPQVTLSLPGAQVAGGELLVGEGVFKMPTVTVPQLELDVGLSREAQA 1233

Query: 2007 MDVSVPKVEGEMKVPDVDIKGPKMDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKAEGP 2066
             + +  +    +K+P +   G +  +     +   P        + +P   +        
Sbjct: 1234 GEAATGEGGLRLKLPTL---GARARVGGEGAEEQPPGAERTFC-LSLPDVELSPSGGNHA 1289

Query: 2067 EVDVNLPKADVVVSGPKVDVEVPDVSL----EGPEG--KLKGPKLKMPEMHFKAPKISMP 2120
            E  V   + +   +G K+ V +P   L    EG E   K K PKL++P + F   ++   
Sbjct: 1290 EYQVAEGEGE---AGHKLKVRLPRFGLVRAKEGAEEGEKAKSPKLRLPRVGFSQSEM--- 1343

Query: 2121 DVDLHLKGPKVKGDVDVSLPKLEGDLTGPS-----VDVEVPDVELECPDAKLKG------ 2169
                 + G       +    + EG   G S     V V +P V L  P    +G      
Sbjct: 1344 -----VTGEGSPSPEEEEEEEEEGSGEGASGRRGRVRVRLPRVGLAAPSKASRGQEGDAA 1398

Query: 2170 PKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMD 2203
            PK  + E   K+PK   P V+L+ K     GD +
Sbjct: 1399 PKSPVRE---KSPKFRFPRVSLSPKARSGSGDQE 1429



 Score =  240 bits (612), Expect = 3e-62
 Identities = 366/1508 (24%), Positives = 659/1508 (43%), Gaps = 316/1508 (20%)

Query: 3983 KLKGPKFKMPEMNIKA----PKISMPDFDLHLKGPKVKGDVDVSLPK---MEGDLKAPEV 4035
            ++KGP+ K+ ++NI++     K  M    L +       DV+ S PK   +   LKA  V
Sbjct: 116  EIKGPRAKVAKLNIQSLSPVKKKKMVPGALGVPADLAPVDVEFSFPKFSRLRRGLKAEAV 175

Query: 4036 DIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVNLPKADIDVS-GP 4094
              KGP        V        L++P++++ + +                KA ++     
Sbjct: 176  --KGP--------VPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAA 225

Query: 4095 KVDIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKMKGDVDVSLPKV 4154
                  P +++ GP         ++P   +  P++S P+        +  G   + LP +
Sbjct: 226  GARFTAPQVELVGP---------RLPGAEVGVPQVSAPKA---APSAEAAGGFALHLPTL 273

Query: 4155 EGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPK 4214
                  P   ++ P V I VP V++        +P       ++P  +     V V +P 
Sbjct: 274  GLGAPAPPA-VEAPAVGIQVPQVELPALPSLPTLP-------TLPCLETREGAVSVVVPT 325

Query: 4215 ADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGD 4274
              LDV+ P V +D+    + G + + +G   + PE+ +K P++S P F     G + K  
Sbjct: 326  --LDVAAPTVGVDLA---LPGAEVEARG---EAPEVALKMPRLSFPRF-----GARAKEV 372

Query: 4275 VDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGP 4334
             +  + KV      PE  +KGP++ +    + +  P      P+V   K  +P  K    
Sbjct: 373  AEAKVAKVS-----PEARVKGPRLRMPTFGLSLLEP--RPAAPEVVESKLKLPTIK---- 421

Query: 4335 DVDVTLPKADIEISGPKVDIDAPDVSIEGPDAKL-KGPKFKMPEMNIKA-PKISMPDIDF 4392
                 +P   I +SGP+V +       +GP+ KL K P+ K+P++   A P++ +P+++ 
Sbjct: 422  -----MPSLGIGVSGPEVKVP------KGPEVKLPKAPEVKLPKVPEAALPEVRLPEVEL 470

Query: 4393 ----NLKGPKVKGDV--DVSLPKVE----GDLKGPEIDIKGPSLDIDTPDVNIEGPEGKL 4442
                 +K PKV      +V LP+VE     ++K P++       ++  P+V +  PE +L
Sbjct: 471  PKVSEMKLPKVPEMAVPEVRLPEVELPKVSEMKLPKVP------EMAVPEVRL--PEVQL 522

Query: 4443 -KGPKFKMPEM-NIKAPKISMPDFDL----HLKGPKVKGDV-------DVSLPKVESDLK 4489
             K  + K+P++  +  P++ +P+  L     +K P+V           +V LPKV  ++K
Sbjct: 523  LKVSEMKLPKVPEMAVPEVRLPEVQLPKVSEMKLPEVSEVAVPEVRLPEVQLPKVP-EMK 581

Query: 4490 GPEVDI-EGPEGKLKGPKFKMPDVHF-KSPQISMSDIDL-NLKGPKIKGDMDISVPKLE- 4545
             PE+ + + PE KL  P+ K+P+V   K P++++ D+ L  ++ PK+    ++ +P+++ 
Sbjct: 582  VPEMKLPKVPEMKL--PEMKLPEVQLPKVPEMAVPDVHLPEVQLPKVP---EMKLPEMKL 636

Query: 4546 GDLKGPKVDVKGPKVGIDTPDIDIHGPEGKL-KGPKFKMPDL-HLKAPKISMPEVDLNLK 4603
             ++K PKV    P++ +     D+H PE +L K P+ K+P +  +  P++ +PEV L   
Sbjct: 637  PEVKLPKV----PEMAVP----DVHLPEVQLPKVPEMKLPKMPEMAVPEVRLPEVQL--- 685

Query: 4604 GPKVKGDMDISLPKVEG----DLKGPEVDIRDPKV-DIDVPDVDVQGPDWHLKMPKVKMP 4658
             PKV    ++ LPKV      D+  PEV +  PKV ++ VPD         +K+P++K+P
Sbjct: 686  -PKVS---EMKLPKVPEMAVPDVHLPEVQL--PKVCEMKVPD---------MKLPEIKLP 730

Query: 4659 KFSMPGFKGEGPDV---DVNLPKADIDVSGPKVDVD-VPDVNI---------EGPDAKLK 4705
            K          PDV   +V LPK   ++  P++ V  VPDV++           P+ +LK
Sbjct: 731  KVPEMAV----PDVHLPEVQLPKVS-EIRLPEMQVPKVPDVHLPKAPEVKLPRAPEVQLK 785

Query: 4706 GPKFKMPE---MSIKAPKISMPDIDL---------NLKGPKVKGDVDVTLPKVEGDLKGP 4753
              K +  E      K PK++MP +              G +V G + VTLP ++ ++ G 
Sbjct: 786  ATKAEQAEGMEFGFKMPKMTMPKLGRAESPSRGKPGEAGAEVSGKL-VTLPCLQPEVDG- 843

Query: 4754 EADIKGPKVDINTPDVDVHGP-DWHLKMPKVKMPKFSMPGFKGEGPDV-----DVSLPKA 4807
            EA +  P + + + ++D+ G      ++P  KM K    G + EGP+V     +V     
Sbjct: 844  EAHVGVPSLTLPSVELDLPGALGLQGQVPAAKMGK----GERVEGPEVAAGVREVGFRVP 899

Query: 4808 DIDVSGPKVD-VDIPDVNIEGPDAKLK-GPKFKMPEINIKAPKISIPDVDLDLKGPKVK- 4864
             +++  P++  V+I +  +E  + K+K   KF +P+  +  PK++  + +   +  K+K 
Sbjct: 900  SVEIVTPQLPAVEIEEGRLEMIETKVKPSSKFSLPKFGLSGPKVAKAEAEGAGRATKLKV 959

Query: 4865 GDFDVSVPKVEGTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLH 4924
              F +S+PK      G E + KG            +G +  +P+L++S P+++   +D H
Sbjct: 960  SKFAISLPKAR---VGAEAEAKG------------AGEAGLLPALDLSIPQLS---LDAH 1001

Query: 4925 LKAPKIGFSGPKLEGGEVDLKGPKVEAPSLDVHMDSPDI--------NIEGPD------V 4970
            L + K+     ++ G ++  KGP+   P   V     +          +EG        V
Sbjct: 1002 LPSGKV-----EVAGADLKFKGPRFALPKFGVRGRDTEAAELVPGVAELEGKGWGWDGRV 1056

Query: 4971 KIPKFKKPKFGFGAKSPKADIKSP--SLDVTVPEAELNLETPEISVGGKGKKSKFKMP-K 5027
            K+PK K P FG  A+  +A+++    S         + L+ PE+ +   G + + +    
Sbjct: 1057 KMPKLKMPSFGL-ARGKEAEVQGDRASPGEKAESTAVQLKIPEVELVTLGAQEEGRAEGA 1115

Query: 5028 IHMSGPKIKAKKQGFDLNVPGGEIDASLKAPDVDVNIAGPDAALKVDVKSPKTKKTMFGK 5087
            + +SG ++   K      V     DA L+ P + +++             P+ + T FG 
Sbjct: 1116 VAVSGMQLSGLKVSTAGQVVTEGHDAGLRMPPLGISL-------------PQVELTGFG- 1161

Query: 5088 MYFPDVEFDIKSPKFKAEAPLPSPKLEG--ELQAPDLELSLPAIHVEGLDIKAKAPKVKM 5145
                    +  +P  +A++ +PS +      +Q P + LSLP   V G ++       KM
Sbjct: 1162 --------EAGTPGQQAQSTVPSAEGTAGYRVQVPQVTLSLPGAQVAGGELLVGEGVFKM 1213

Query: 5146 PDVDISVPKIEGDLKGPKVQANLGAPDINIEGLDAKVKTPSFGISAPQ------------ 5193
            P V  +VP++E D+ G   +A  G       GL  ++K P+ G  A              
Sbjct: 1214 PTV--TVPQLELDV-GLSREAQAGEAATGEGGL--RLKLPTLGARARVGGEGAEEQPPGA 1268

Query: 5194 -----VSIPDVNVNLKGP----------------KIKGDVPSVGLEGPDVDLQGPEAKIK 5232
                 +S+PDV ++  G                 K+K  +P  GL       +  E K K
Sbjct: 1269 ERTFCLSLPDVELSPSGGNHAEYQVAEGEGEAGHKLKVRLPRFGLVRAKEGAEEGE-KAK 1327

Query: 5233 FPKFSMPKIGIPGVKM---EGGGAEVHAQLPSLEGDLRG------------PDVKLEGPD 5277
             PK  +P++G    +M   EG  +    +    EG   G            P V L  P 
Sbjct: 1328 SPKLRLPRVGFSQSEMVTGEGSPSPEEEEEEEEEGSGEGASGRRGRVRVRLPRVGLAAPS 1387

Query: 5278 VSLKGPGVDLPS---VNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLSGV 5334
             + +G   D      V    PK   P + L+ K  S  GD +     +++ + G + +G 
Sbjct: 1388 KASRGQEGDAAPKSPVREKSPKFRFPRVSLSPKARSGSGDQEEGGLRVRLPSVGFSETGA 1447

Query: 5335 GGKMQVGG 5342
             G  ++ G
Sbjct: 1448 PGPARMEG 1455



 Score =  239 bits (609), Expect = 8e-62
 Identities = 404/1538 (26%), Positives = 672/1538 (43%), Gaps = 347/1538 (22%)

Query: 2317 VDFNLKGPKIKGDVDVSAPKLEG-ELKGPELDVKGPKLDADMPEVAVEGPNGKWKTPKFK 2375
            V F LK     GD+ +    + G E+KGP   V    + +  P    +   G    P   
Sbjct: 92   VSFCLKRTVPTGDLALRPGTVSGYEIKGPRAKVAKLNIQSLSPVKKKKMVPGALGVPADL 151

Query: 2376 MP-DMHFKAPKISMPDLDLHLKSPKAKGEVD-------VDVPKLE-----GDLKGPHVDV 2422
             P D+ F  PK S   L   LK+   KG V        + +P+L       + +   +  
Sbjct: 152  APVDVEFSFPKFSR--LRRGLKAEAVKGPVPAAPARRRLQLPRLRVREVAEEAQAARLAA 209

Query: 2423 SGPDIDIEGPEGKLKGPKFKMPDMHFKAPNISMPDVDLNLKGPKIKGDVDVSVPEVEGKL 2482
            + P      P  K K          F AP +        L GP++ G  +V VP+V    
Sbjct: 210  AAP------PPRKAKVEAEVAAGARFTAPQVE-------LVGPRLPG-AEVGVPQVSAPK 255

Query: 2483 EVPDMNIRG------PKVDVNAPD---VQAPDWHLKMPKMKMPKF-SMPGFKA------- 2525
              P     G      P + + AP    V+AP   +++P++++P   S+P           
Sbjct: 256  AAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVGIQVPQVELPALPSLPTLPTLPCLETR 315

Query: 2526 EG------PEVDVNLPKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMP--------- 2570
            EG      P +DV  P   VD++ P  ++E      E PE  LK P+L  P         
Sbjct: 316  EGAVSVVVPTLDVAAPTVGVDLALPGAEVEARG---EAPEVALKMPRLSFPRFGARAKEV 372

Query: 2571 ----------EMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKV 2620
                      E  +K P++ MP F L L  P+       +   VE  LK P + +    +
Sbjct: 373  AEAKVAKVSPEARVKGPRLRMPTFGLSLLEPR-----PAAPEVVESKLKLPTIKMPSLGI 427

Query: 2621 DINAPDVGV-QGPDWHL-KMPKVKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPKVDIEG 2678
             ++ P+V V +GP+  L K P+VK+PK        E    +V+LP+ ++    PKV    
Sbjct: 428  GVSGPEVKVPKGPEVKLPKAPEVKLPKVP------EAALPEVRLPEVEL----PKV---- 473

Query: 2679 PDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVE----G 2734
                      ++K P  K+PEM +  P++ +P+++L    PKV    ++ LPKV      
Sbjct: 474  ---------SEMKLP--KVPEMAV--PEVRLPEVEL----PKVS---EMKLPKVPEMAVP 513

Query: 2735 DLKGPEV------DIKGPKV-DIDAPDVDVHGPDWHLKMPKIKMPKISMPGFKGEGPDV- 2786
            +++ PEV      ++K PKV ++  P+V         ++P++++PK+S    + + P+V 
Sbjct: 514  EVRLPEVQLLKVSEMKLPKVPEMAVPEV---------RLPEVQLPKVS----EMKLPEVS 560

Query: 2787 DVNLPKADI-DVSGPKV-DVECPDVNI-EGPEGKWKSPKFKMPEMHF-KTPKISMPDIDL 2842
            +V +P+  + +V  PKV +++ P++ + + PE   K P+ K+PE+   K P++++PD+ L
Sbjct: 561  EVAVPEVRLPEVQLPKVPEMKVPEMKLPKVPE--MKLPEMKLPEVQLPKVPEMAVPDVHL 618

Query: 2843 NLTGPKIKGDVDVTGPKVEGDLKGPEV---DLKGPKV-DIDVPDVNVQGPDWHL-KMPKM 2897
                       +V  PKV  ++K PE+   ++K PKV ++ VPDV++  P+  L K+P+M
Sbjct: 619  ----------PEVQLPKVP-EMKLPEMKLPEVKLPKVPEMAVPDVHL--PEVQLPKVPEM 665

Query: 2898 KMPKFSMPGFKAEGPEV---DVNLPKADVDVSGPKV-DVEGPDVNIEGPEGKL------K 2947
            K+PK  MP      PEV   +V LPK   ++  PKV ++  PDV++  PE +L      K
Sbjct: 666  KLPK--MPEMAV--PEVRLPEVQLPKVS-EMKLPKVPEMAVPDVHL--PEVQLPKVCEMK 718

Query: 2948 GPKFKMPEMNIKAPKIP-MPDFDLHLKGPKVKGDVDISLPKVEGDLKGPEVDIRGPQVDI 3006
             P  K+PE  IK PK+P M   D+HL         ++ LPKV         +IR P  ++
Sbjct: 719  VPDMKLPE--IKLPKVPEMAVPDVHLP--------EVQLPKVS--------EIRLP--EM 758

Query: 3007 DVPDVGVQGPDWHL-KMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDV 3065
             VP V    PD HL K P+VK+P+          P+V +   KA+               
Sbjct: 759  QVPKV----PDVHLPKAPEVKLPR---------APEVQLKATKAE--------------- 790

Query: 3066 NIEGPEGKLKGPKFKMPEM-NIKAPKISMPDIDLNLKGPKVKGDMDVSL----PKVEGDM 3120
              EG E   K PK  MP++   ++P    P       G +V G + V+L    P+V+G+ 
Sbjct: 791  QAEGMEFGFKMPKMTMPKLGRAESPSRGKP----GEAGAEVSGKL-VTLPCLQPEVDGEA 845

Query: 3121 KVPDVDIKGPKVDINAPD-VDVQGPDWHLKMPKIKMPKISMPGFKGEGPEV-----DVNL 3174
             V    +  P V+++ P  + +QG     ++P  KM K    G + EGPEV     +V  
Sbjct: 846  HVGVPSLTLPSVELDLPGALGLQG-----QVPAAKMGK----GERVEGPEVAAGVREVGF 896

Query: 3175 PKADLDVSGPKVD-VDVPDVNIEGPDAKLK-GPKFKMPEMNIKAPKISMPDLD-----LN 3227
                +++  P++  V++ +  +E  + K+K   KF +P+  +  PK++  + +       
Sbjct: 897  RVPSVEIVTPQLPAVEIEEGRLEMIETKVKPSSKFSLPKFGLSGPKVAKAEAEGAGRATK 956

Query: 3228 LKGPKMKGEVDVSLANVEGDLKG-------PALDIKGPKIDVDA----PDIDIHGPDAKL 3276
            LK  K    +  +    E + KG       PALD+  P++ +DA      +++ G D K 
Sbjct: 957  LKVSKFAISLPKARVGAEAEAKGAGEAGLLPALDLSIPQLSLDAHLPSGKVEVAGADLKF 1016

Query: 3277 KGPKLKMPDMHVNMPKISMPEI---DLNLKGSKLKGDVDVSGPKLEGDIKAPSLDI-KGP 3332
            KGP+  +P   V        E+      L+G     D  V  PKL    K PS  + +G 
Sbjct: 1017 KGPRFALPKFGVRGRDTEAAELVPGVAELEGKGWGWDGRVKMPKL----KMPSFGLARGK 1072

Query: 3333 EVDVSGPKLNIEGKSKKS--RFKLPKFNFSGSKVQTP-----EVDVKGKKPDIDITGPKV 3385
            E +V G + +   K++ +  + K+P+        Q        V V G    + ++G KV
Sbjct: 1073 EAEVQGDRASPGEKAESTAVQLKIPEVELVTLGAQEEGRAEGAVAVSG----MQLSGLKV 1128

Query: 3386 DINAPDVEVQGKVKGSKFKMPFLSISSPKVSMPDV-ELNLKSPKVKGDLDIAGPNLEGDF 3444
               A  V  +G   G   +MP L IS P+V +    E      + +  +    P+ EG  
Sbjct: 1129 S-TAGQVVTEGHDAG--LRMPPLGISLPQVELTGFGEAGTPGQQAQSTV----PSAEGT- 1180

Query: 3445 KGPKVDIKAPEVNLNAPDVDVHGPDWNLKMPKMKMPKFSVSGLKAEGPDVAVDLPKGDIN 3504
             G +V +  P+V L+ P   V G +  +     KMP  +V  L+ +   ++ +   G+  
Sbjct: 1181 AGYRVQV--PQVTLSLPGAQVAGGELLVGEGVFKMPTVTVPQLELD-VGLSREAQAGEAA 1237

Query: 3505 IEGPSMNIEGPDLNVEGPEGGLKGPKFKMPDMNIKAPKISMPDIDLNLKGPKVKGDVDIS 3564
                 + ++ P L      GG +G + + P    +   +S+PD++L+   P      +  
Sbjct: 1238 TGEGGLRLKLPTLGARARVGG-EGAEEQPPGAE-RTFCLSLPDVELS---PSGGNHAEYQ 1292

Query: 3565 LPKLEGDLKGPEVDIKGPKVDINAPDVDVHGPDWHLKMPKVKMPKFSMP--GFK------ 3616
            + + EG+  G ++ ++ P+  +      V   +   +  K K PK  +P  GF       
Sbjct: 1293 VAEGEGE-AGHKLKVRLPRFGL------VRAKEGAEEGEKAKSPKLRLPRVGFSQSEMVT 1345

Query: 3617 GEGPEVDVTLPKADIDISGP-------NVDVDVPDVNIEGPDAKLKG------PKFKMPE 3663
            GEG        + + + SG         V V +P V +  P    +G      PK  + E
Sbjct: 1346 GEGSPSPEEEEEEEEEGSGEGASGRRGRVRVRLPRVGLAAPSKASRGQEGDAAPKSPVRE 1405

Query: 3664 MNIKAPKISMPDFDLNLK-----GPKMKGDVVVSLPKV 3696
               K+PK   P   L+ K     G + +G + V LP V
Sbjct: 1406 ---KSPKFRFPRVSLSPKARSGSGDQEEGGLRVRLPSV 1440



 Score =  236 bits (603), Expect = 4e-61
 Identities = 385/1596 (24%), Positives = 695/1596 (43%), Gaps = 283/1596 (17%)

Query: 9    ELLLPNWQGSGSHGLTIAQRD-DGVFVQEVTQNSPAARTGVVKEGDQIVGATIYFDNLQS 67
            E+++     +G  G+ +A    +G+FV+E+ ++SPAAR+  ++EGDQ++ A ++F+N + 
Sbjct: 18   EIIVETEAQTGVSGINVAGGGKEGIFVRELREDSPAARSLSLQEGDQLLSARVFFENFKY 77

Query: 68   GEVTQLLNTMGHHTVGLKLHR---KGDRSPEPGQTWTREVFSSCSSEVVLSGDDEEYQRI 124
             +  +LL     + V   L R    GD +  PG     E+    +    L+      Q +
Sbjct: 78   EDALRLLQCAEPYKVSFCLKRTVPTGDLALRPGTVSGYEIKGPRAKVAKLN-----IQSL 132

Query: 125  YTTKIKPRLKSEDGVEGDLGETQSRTITVTRRVTAYTVDVTGREGAKDIDISSP------ 178
               K K  +    GV  DL               ++      R G K   +  P      
Sbjct: 133  SPVKKKKMVPGALGVPADLAPVDVE--------FSFPKFSRLRRGLKAEAVKGPVPAAPA 184

Query: 179  EFKIKIPRHELTEISNVDVETQSGKTVIRLPSGSGAASPTGSAVDIR--AGAISASGPEL 236
              ++++PR  + E++    E Q+ +     P    A      A   R  A  +   GP L
Sbjct: 185  RRRLQLPRLRVREVAE---EAQAARLAAAAPPPRKAKVEAEVAAGARFTAPQVELVGPRL 241

Query: 237  QGAGHSKLQVTMPGIKVGGSGVNVNAKGLDLGGRGGVQVPAVDISSSLGGRAVEVQGPSL 296
             GA     QV+ P            A  L   G G    PAV+ + ++G +  +V+ P+L
Sbjct: 242  PGAEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPPAVE-APAVGIQVPQVELPAL 300

Query: 297  ESGDHGKIKFPTMKVPKFGVSTGREG-----------QTPKAGLRVSAPEVSVGHKGGKP 345
             S        PT+  P       REG             P  G+ ++ P   V  +G  P
Sbjct: 301  PS-------LPTL--PTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEARGEAP 351

Query: 346  GLTIQAPQL----------EVSVPSANIEGLEGKLKGPQITGPSLEGDLGLKGAKPQGHI 395
             + ++ P+L          EV+         E ++KGP++  P+     GL   +P+   
Sbjct: 352  EVALKMPRLSFPRFGARAKEVAEAKVAKVSPEARVKGPRLRMPT----FGLSLLEPR--- 404

Query: 396  GVDASAPQIGGSITGPSVEVQAPDIDVQGPGSKLNVPKMKVPKFSVSGAKGEETGIDVTL 455
                +AP++  S      +++ P I +   G  ++ P++KVPK           G +V L
Sbjct: 405  ---PAAPEVVES------KLKLPTIKMPSLGIGVSGPEVKVPK-----------GPEVKL 444

Query: 456  PTG-EVTVPGVSGDVSLPEIATGGLE-GKMKGTKV-KTPEMIIQKPKISMQDVDL-SLGS 511
            P   EV +P V  + +LPE+    +E  K+   K+ K PEM +  P++ + +V+L  +  
Sbjct: 445  PKAPEVKLPKVP-EAALPEVRLPEVELPKVSEMKLPKVPEMAV--PEVRLPEVELPKVSE 501

Query: 512  PKLKGDIKVSAPGVQGDVKGPQVALKGSRVDIETPNLEGTLTGPRLGSPSGKTGTCRISM 571
             KL    +++ P    +V+ P+V L     +++ P +      P +  P        + +
Sbjct: 502  MKLPKVPEMAVP----EVRLPEVQLL-KVSEMKLPKV------PEMAVP-------EVRL 543

Query: 572  SEVDLNVAAPKVKGGVDVTLPRVEGKVKVPEV---DVRGPKV-DVSAPDVE-AHGPEWNL 626
             EV L    PKV    ++ LP V  +V VPEV   +V+ PKV ++  P+++    PE  +
Sbjct: 544  PEVQL----PKVS---EMKLPEV-SEVAVPEVRLPEVQLPKVPEMKVPEMKLPKVPE--M 593

Query: 627  KMPKMKMPTFSTPGAKGEG-PDVHMTLPKGDISISGPKVNVEAPDVNLEGLGGKLKGPDV 685
            K+P+MK+P    P       PDVH+        +  PKV    P++ L     ++K P+V
Sbjct: 594  KLPEMKLPEVQLPKVPEMAVPDVHLP------EVQLPKV----PEMKLP----EMKLPEV 639

Query: 686  KLPDMSVKTPKISMPDVDLHVKGTKVKGEYDVTVPKLEGELKGPKV-DIDAPDVDVHGPD 744
            KLP    K P++++PDV L           +V +PK+  E+K PK+ ++  P+V +  P+
Sbjct: 640  KLP----KVPEMAVPDVHLP----------EVQLPKVP-EMKLPKMPEMAVPEVRL--PE 682

Query: 745  WHL-KMPKMKMPKFSVPGFKAEGPEVDVNLPKADVDISGPKI-DVTAPDVSIEEPEGKL- 801
              L K+ +MK+PK  VP    E    DV+LP+  +    PK+ ++  PD+ +  PE KL 
Sbjct: 683  VQLPKVSEMKLPK--VP----EMAVPDVHLPEVQL----PKVCEMKVPDMKL--PEIKLP 730

Query: 802  KGPKFKMPEMNIKVPKISMPDV-DLHLKGPNVKGEYDVTMPKVESEIKV---PDVELKSA 857
            K P+  +P++++  P++ +P V ++ L    V    DV +PK   E+K+   P+V+LK+ 
Sbjct: 731  KVPEMAVPDVHL--PEVQLPKVSEIRLPEMQVPKVPDVHLPKA-PEVKLPRAPEVQLKAT 787

Query: 858  KMDIDVPDVEVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVGVEV 917
            K +      + +G ++  KMPKM MPK      +AE P       +A  ++SG  V +  
Sbjct: 788  KAE------QAEGMEFGFKMPKMTMPKLG----RAESPSRG-KPGEAGAEVSGKLVTLPC 836

Query: 918  PDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGP-KVKGEYDMTVPKLEGDLK 976
                ++G             E ++  P +++P V+L + G   ++G+           ++
Sbjct: 837  LQPEVDG-------------EAHVGVPSLTLPSVELDLPGALGLQGQVPAAKMGKGERVE 883

Query: 977  GPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGPEFDVNLSKANVDISAPKVDT 1036
            GP+V     +V  + P   +  P  ++P   +   + E  E  V   K +   S PK   
Sbjct: 884  GPEVAAGVREVGFRVPSVEIVTP--QLPAVEIEEGRLEMIETKV---KPSSKFSLPKFGL 938

Query: 1037 NAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKGPKMKG---NVDISAPKIE 1093
            + P ++    EG  +  K K+ +     PK  +   + + KG    G    +D+S P++ 
Sbjct: 939  SGPKVAKAEAEGAGRATKLKVSKFAISLPKARV-GAEAEAKGAGEAGLLPALDLSIPQLS 997

Query: 1094 GEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLKGEGPEVDVNLPKA 1153
             +  +P            +  VE  G D   K P+  +PKF +     E  E+   + + 
Sbjct: 998  LDAHLP------------SGKVEVAGADLKFKGPRFALPKFGVRGRDTEAAELVPGVAEL 1045

Query: 1154 DVVVSGPKVDIEAPDVSL------EGPEGKLKGPKFKMPEMHFKTP-KISMPDVDLHLKG 1206
            +    G    ++ P + +       G E +++G +    E    T  ++ +P+V+L   G
Sbjct: 1046 EGKGWGWDGRVKMPKLKMPSFGLARGKEAEVQGDRASPGEKAESTAVQLKIPEVELVTLG 1105

Query: 1207 PKVKGDVDVSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMPKM--KMPKFSM 1264
             + +G       + EG + V  +++ G K+   A  V  +G D  L+MP +   +P+  +
Sbjct: 1106 AQEEG-------RAEGAVAVSGMQLSGLKVS-TAGQVVTEGHDAGLRMPPLGISLPQVEL 1157

Query: 1265 PGFKGE----GREVDVNLPKADIDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKA 1320
             GF GE    G++    +P A+   +G +  V+VP V+L  P  ++ G +  + E  FK 
Sbjct: 1158 TGF-GEAGTPGQQAQSTVPSAE-GTAGYR--VQVPQVTLSLPGAQVAGGELLVGEGVFKM 1213

Query: 1321 PKISMPDVDLNLKGPKLKGDVDVSLPEVEGEMKVPDVDIKGPKVDISAPDVDVHGP---- 1376
            P +++P ++L++   +     + +  E    +K+P +   G +  +     +   P    
Sbjct: 1214 PTVTVPQLELDVGLSREAQAGEAATGEGGLRLKLPTL---GARARVGGEGAEEQPPGAER 1270

Query: 1377 DWHLKMPKVKM-------PKFSMPGFKGE-GPEVDVKLPKADVDVSGPKMDAEVPDVNIE 1428
             + L +P V++        ++ +   +GE G ++ V+LP+    +   K  AE      E
Sbjct: 1271 TFCLSLPDVELSPSGGNHAEYQVAEGEGEAGHKLKVRLPR--FGLVRAKEGAE------E 1322

Query: 1429 GPDAKLKGPKFKMPEMSIKPQKISIPDVGLHLKGPKMKGDYDVTVPKVEGEIKAPDVDIK 1488
            G   K K PK ++P +     ++     G     P+ + + +          +   V ++
Sbjct: 1323 G--EKAKSPKLRLPRVGFSQSEMV---TGEGSPSPEEEEEEEEEGSGEGASGRRGRVRVR 1377

Query: 1489 GPKVDINAPDVEVHGP--DWHLKMP-KVKMPKFSMP 1521
             P+V + AP     G   D   K P + K PKF  P
Sbjct: 1378 LPRVGLAAPSKASRGQEGDAAPKSPVREKSPKFRFP 1413



 Score =  235 bits (600), Expect = 9e-61
 Identities = 377/1468 (25%), Positives = 654/1468 (44%), Gaps = 302/1468 (20%)

Query: 1075 DLKGPKMKG---NVDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKM 1131
            ++KGP+ K    N+   +P ++ +  VP     G   D+   DVE               
Sbjct: 116  EIKGPRAKVAKLNIQSLSP-VKKKKMVPGA--LGVPADLAPVDVE------------FSF 160

Query: 1132 PKFSM--PSLKGEGPEVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGP-----KFK 1184
            PKFS     LK E  +  V    A   +  P++ +   +V+ E    +L        K K
Sbjct: 161  PKFSRLRRGLKAEAVKGPVPAAPARRRLQLPRLRVR--EVAEEAQAARLAAAAPPPRKAK 218

Query: 1185 MPEMHFKTPKISMPDVDLHLKGPKVKGDVDVSVPKVEGEMKVPDVEIKG------PKMDI 1238
            +        + + P V+L   GP++ G  +V VP+V      P  E  G      P + +
Sbjct: 219  VEAEVAAGARFTAPQVEL--VGPRLPG-AEVGVPQVSAPKAAPSAEAAGGFALHLPTLGL 275

Query: 1239 DAP-DVEVQGPDWHLKMPKMKMPKF-SMPGFKG----EGREVDVNLPKADIDVSGPKVDV 1292
             AP    V+ P   +++P++++P   S+P        E RE  V++    +DV+ P V V
Sbjct: 276  GAPAPPAVEAPAVGIQVPQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGV 335

Query: 1293 EVPDVSLEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLNLKGPKLKGDVDVSLPEVEGEM 1352
               D++L G E + +G   + PE+  K P++S P       G + K   +  + +V  E 
Sbjct: 336  ---DLALPGAEVEARG---EAPEVALKMPRLSFPRF-----GARAKEVAEAKVAKVSPEA 384

Query: 1353 KVPDVDIKGPKVDISAPDVDVHGPDW---HLKMPKVKMPKFSMPGFKGEGPEV------D 1403
            +V    ++ P   +S  +     P+     LK+P +KMP     G    GPEV      +
Sbjct: 385  RVKGPRLRMPTFGLSLLEPRPAAPEVVESKLKLPTIKMPSL---GIGVSGPEVKVPKGPE 441

Query: 1404 VKLPKADVDVSGPKM-DAEVPDVNIEGPDAKLKGPKF------KMPEMSIKPQKISIPDV 1456
            VKLPKA  +V  PK+ +A +P+V +  P+ +L  PK       K+PEM++   ++ +P+V
Sbjct: 442  VKLPKAP-EVKLPKVPEAALPEVRL--PEVEL--PKVSEMKLPKVPEMAVP--EVRLPEV 494

Query: 1457 GLHLKGPKMKGDYDVTVPKVEG----EIKAPDV------DIKGPKVDINAPDVEVHGPDW 1506
             L    PK+    ++ +PKV      E++ P+V      ++K PKV    P++ V     
Sbjct: 495  EL----PKVS---EMKLPKVPEMAVPEVRLPEVQLLKVSEMKLPKV----PEMAVP---- 539

Query: 1507 HLKMPKVKMPKFSMPGFKGEGPEV------DMNLPKADLGVSGPKV-DIDVPDVNL-EAP 1558
             +++P+V++PK S    + + PEV      ++ LP+  L    PKV ++ VP++ L + P
Sbjct: 540  EVRLPEVQLPKVS----EMKLPEVSEVAVPEVRLPEVQL----PKVPEMKVPEMKLPKVP 591

Query: 1559 EGKLKGPKFKMPSMNI-QTHKISMPDVGLNLKAPKLKTDVDVSLPKVEGDLKGPEI---D 1614
            E KL  P+ K+P + + +  ++++PDV L           +V LPKV  ++K PE+   +
Sbjct: 592  EMKL--PEMKLPEVQLPKVPEMAVPDVHLP----------EVQLPKVP-EMKLPEMKLPE 638

Query: 1615 VKAPKM-DVNVGDIDIEGPEGKL-KGPKFKMPEM-HFKAPKISMPDVDLHLKGPKVKGDM 1671
            VK PK+ ++ V D+ +  PE +L K P+ K+P+M     P++ +P+V L    PKV    
Sbjct: 639  VKLPKVPEMAVPDVHL--PEVQLPKVPEMKLPKMPEMAVPEVRLPEVQL----PKVS--- 689

Query: 1672 DVSVPKVEGEMKVPDV---DIKGPKV-DIDAPDVEVHDPDWHL-KMPKMKMPKFSMPGFK 1726
            ++ +PKV  EM VPDV   +++ PKV ++  PD+++  P+  L K+P+M +P   +P  +
Sbjct: 690  EMKLPKVP-EMAVPDVHLPEVQLPKVCEMKVPDMKL--PEIKLPKVPEMAVPDVHLP--E 744

Query: 1727 AEGPEV-DVNLPKADIDVSGPSVDTDAPDLDI-EGPEGKLKGSKFKMPKLNIKAPKVSMP 1784
             + P+V ++ LP+  +    P V    PD+ + + PE KL     + P++ +KA K    
Sbjct: 745  VQLPKVSEIRLPEMQV----PKV----PDVHLPKAPEVKLP----RAPEVQLKATKAEQA 792

Query: 1785 D-VDLNLKGPKLKGEIDASVPELEGDLRGPQVDVKGPFVEAEVPD--VDLECPDAKLKGP 1841
            + ++   K PK+      ++P+L G    P     G    AEV    V L C   ++ G 
Sbjct: 793  EGMEFGFKMPKM------TMPKL-GRAESPSRGKPGE-AGAEVSGKLVTLPCLQPEVDG- 843

Query: 1842 KFKMPEMHFKAPKISMPDVDLHL----------------KGPKVKGDADVSVPKLEGDLT 1885
                 E H   P +++P V+L L                KG +V+G  +V+    E    
Sbjct: 844  -----EAHVGVPSLTLPSVELDLPGALGLQGQVPAAKMGKGERVEGP-EVAAGVREVGFR 897

Query: 1886 GPSV--------GVEVPDVELECPDAKLK-GPKFKMPDMHFKAPKISMPDVDLHLKGPKV 1936
             PSV         VE+ +  LE  + K+K   KF +P      PK++  + +   +  K+
Sbjct: 898  VPSVEIVTPQLPAVEIEEGRLEMIETKVKPSSKFSLPKFGLSGPKVAKAEAEGAGRATKL 957

Query: 1937 K-GDVDVSVPKL----EGDLTGPSVGVEVPDVELECPDAKLKGPKFKMPEMHFKTPKISM 1991
            K     +S+PK     E +  G      +P ++L  P   L        + H  + K+ +
Sbjct: 958  KVSKFAISLPKARVGAEAEAKGAGEAGLLPALDLSIPQLSL--------DAHLPSGKVEV 1009

Query: 1992 PDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKMDIDAPDVDVHGPDW--HLKMP 2049
               DL  KGP+       ++PK      V   D +  ++     +++  G  W   +KMP
Sbjct: 1010 AGADLKFKGPRF------ALPK----FGVRGRDTEAAELVPGVAELEGKGWGWDGRVKMP 1059

Query: 2050 KMKMPKFSM--------------PGFKAEGPEVDVNLPKADVVVSGPKVD------VEVP 2089
            K+KMP F +              PG KAE   V + +P+ ++V  G + +      V V 
Sbjct: 1060 KLKMPSFGLARGKEAEVQGDRASPGEKAESTAVQLKIPEVELVTLGAQEEGRAEGAVAVS 1119

Query: 2090 DVSLEGPEGKLKGPKLKMPEMHFKAPKISMPDVDLHLKGPKVKGDVDVSLPKLEGDLTGP 2149
             + L G +    G  +   E H     + MP + + L   ++ G  +   P  +   T P
Sbjct: 1120 GMQLSGLKVSTAGQVVT--EGHDAG--LRMPPLGISLPQVELTGFGEAGTPGQQAQSTVP 1175

Query: 2150 SVD------VEVPDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMD 2203
            S +      V+VP V L  P A++ G +  + E  FK P +++P + L++   +     +
Sbjct: 1176 SAEGTAGYRVQVPQVTLSLPGAQVAGGELLVGEGVFKMPTVTVPQLELDVGLSREAQAGE 1235

Query: 2204 VSVPKVEGEMKVPDVDIRGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKGEGPEV 2263
             +  +    +K+P +  R  +V  +  +    G +   +   + +P   +    G   E 
Sbjct: 1236 AATGEGGLRLKLPTLGARA-RVGGEGAEEQPPGAE---RTFCLSLPDVELSPSGGNHAEY 1291

Query: 2264 DVNLPKADVDVSGPKVDVEVPDVSL-EGPEGKLKGPKFKMPEMHFKTPKISMPDVDFN-- 2320
             V   + +   +G K+ V +P   L    EG  +G K        K+PK+ +P V F+  
Sbjct: 1292 QVAEGEGE---AGHKLKVRLPRFGLVRAKEGAEEGEK-------AKSPKLRLPRVGFSQS 1341

Query: 2321 --LKGPKIKGDVDVSAPKLEGELKGP-----ELDVKGPKLDADMPEVAVEGPNGKWKTPK 2373
              + G       +    + EG  +G       + V+ P++    P  A  G  G    PK
Sbjct: 1342 EMVTGEGSPSPEEEEEEEEEGSGEGASGRRGRVRVRLPRVGLAAPSKASRGQEGD-AAPK 1400

Query: 2374 FKMPDMHFKAPKISMPDLDLHLKSPKAK 2401
              + +   K+PK   P + L   SPKA+
Sbjct: 1401 SPVRE---KSPKFRFPRVSL---SPKAR 1422



 Score =  227 bits (578), Expect = 3e-58
 Identities = 364/1467 (24%), Positives = 653/1467 (44%), Gaps = 303/1467 (20%)

Query: 3653 KLKGPKFKMPEMNIKA----PKISMPDFDLNLKGPKMKGDVVVSLPKVEGDLKGPEVD-I 3707
            ++KGP+ K+ ++NI++     K  M    L +       DV  S PK     +G + + +
Sbjct: 116  EIKGPRAKVAKLNIQSLSPVKKKKMVPGALGVPADLAPVDVEFSFPKFSRLRRGLKAEAV 175

Query: 3708 KGP------KVDIDTPDINI-----EGSEGKFKGP-----KFKIPEMHLKAPKISMPDID 3751
            KGP      +  +  P + +     E    +         K K+        + + P ++
Sbjct: 176  KGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGARFTAPQVE 235

Query: 3752 LNLKGPKVKGDVDVSLPKMEGDLKGPEVDIKG------PKVDINAPDVD-VQGPDWHLKM 3804
            L   GP++ G  +V +P++      P  +  G      P + + AP    V+ P   +++
Sbjct: 236  L--VGPRLPG-AEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVGIQV 292

Query: 3805 PKVKMPKF-------SMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEG----PE 3853
            P+V++P         ++P  +     V V +P  D+      VD+ +P   +E     PE
Sbjct: 293  PQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEARGEAPE 352

Query: 3854 GKLKGPKFKMP-------------------EMNIKAPKISMPDIDLNLKGPKVKGDMDVS 3894
              LK P+   P                   E  +K P++ MP   L+L  P+       +
Sbjct: 353  VALKMPRLSFPRFGARAKEVAEAKVAKVSPEARVKGPRLRMPTFGLSLLEPR-----PAA 407

Query: 3895 LPKVEGDMQVPDLDIKGPKVDINAPDVDV-RGPDWHL-KMPKIKMPKISMPGFKGEGPEV 3952
               VE  +++P + +    + ++ P+V V +GP+  L K P++K+PK+         PEV
Sbjct: 408  PEVVESKLKLPTIKMPSLGIGVSGPEVKVPKGPEVKLPKAPEVKLPKVPEAAL----PEV 463

Query: 3953 ---DVNLPKADLDVSGPKV-DVDVPDVNIEGPDAKL-KGPKFKMPEM-NIKAPKISMPDF 4006
               +V LPK   ++  PKV ++ VP+V +  P+ +L K  + K+P++  +  P++ +P+ 
Sbjct: 464  RLPEVELPKVS-EMKLPKVPEMAVPEVRL--PEVELPKVSEMKLPKVPEMAVPEVRLPEV 520

Query: 4007 DL----HLKGPKVKGDV-------DVSLPKMEGDLKAPEV-DIKGPKV---DIDAPDV-D 4050
             L     +K PKV           +V LPK+  ++K PEV ++  P+V   ++  P V +
Sbjct: 521  QLLKVSEMKLPKVPEMAVPEVRLPEVQLPKVS-EMKLPEVSEVAVPEVRLPEVQLPKVPE 579

Query: 4051 VHGPDWHL-KMPKVKMPKFSMPGFK-GEGPEV---DVNLPKADIDVSGPKV-DIDTPDID 4104
            +  P+  L K+P++K+P+  +P  +  + PE+   DV+LP+  +    PKV ++  P++ 
Sbjct: 580  MKVPEMKLPKVPEMKLPEMKLPEVQLPKVPEMAVPDVHLPEVQL----PKVPEMKLPEMK 635

Query: 4105 IHGPEGKL-KGPKFKMPDLHLKAPKISMPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPEV 4163
            +  PE KL K P+  +PD+HL  P++ +P+V   +K PKM    ++++P+V    + PEV
Sbjct: 636  L--PEVKLPKVPEMAVPDVHL--PEVQLPKVP-EMKLPKMP---EMAVPEV----RLPEV 683

Query: 4164 DIKGPKV-DIDVPDV-DVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSG 4221
             +  PKV ++ +P V ++  PD HL  P+V++PK        E    D+ LP+  L    
Sbjct: 684  QL--PKVSEMKLPKVPEMAVPDVHL--PEVQLPKVC------EMKVPDMKLPEIKL---- 729

Query: 4222 PKV-DIDVPDVNIEGPDAKL-KGPKFKMPEMNIKAPKISMPDFDLHL-KGPKVKGDVDVS 4278
            PKV ++ VPDV++  P+ +L K  + ++PEM +  PK+     D+HL K P+VK      
Sbjct: 730  PKVPEMAVPDVHL--PEVQLPKVSEIRLPEMQV--PKVP----DVHLPKAPEVK------ 775

Query: 4279 LPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMP-----GFKGE- 4332
            LP+       PEV +K  K +         G ++  KMPK+ MPK         G  GE 
Sbjct: 776  LPRA------PEVQLKATKAE------QAEGMEFGFKMPKMTMPKLGRAESPSRGKPGEA 823

Query: 4333 GPDVD---VTLPKADIEISG-----------PKVDIDAPD-VSIEG--PDAKL-KGPKFK 4374
            G +V    VTLP    E+ G           P V++D P  + ++G  P AK+ KG + +
Sbjct: 824  GAEVSGKLVTLPCLQPEVDGEAHVGVPSLTLPSVELDLPGALGLQGQVPAAKMGKGERVE 883

Query: 4375 MPEMNIKAPKISMPDIDFNLKGPKVKGDVDVSLPKVE---GDLKGPEIDIKGPSLDIDTP 4431
             PE+        + ++ F +   ++   V   LP VE   G L+  E  +K PS     P
Sbjct: 884  GPEV-----AAGVREVGFRVPSVEI---VTPQLPAVEIEEGRLEMIETKVK-PSSKFSLP 934

Query: 4432 DVNIEGP-------EGKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKG---DVDVSL 4481
               + GP       EG  +  K K+ +  I  PK  +   +   KG    G    +D+S+
Sbjct: 935  KFGLSGPKVAKAEAEGAGRATKLKVSKFAISLPKARV-GAEAEAKGAGEAGLLPALDLSI 993

Query: 4482 PKVESDLKGP--EVDIEGPEGKLKGPKFKMPDVHFKSPQISMSDIDLNLKGPKIKGDMDI 4539
            P++  D   P  +V++ G + K KGP+F +P    +      +++        + G    
Sbjct: 994  PQLSLDAHLPSGKVEVAGADLKFKGPRFALPKFGVRGRDTEAAEL--------VPG---- 1041

Query: 4540 SVPKLEGDLKGPKVDVKGPKVGIDTPDIDIHGPEGKLKGPKFKMPD-LHLKAPKISMPEV 4598
             V +LEG   G    VK PK+ + +  +   G E +++G +    +     A ++ +PEV
Sbjct: 1042 -VAELEGKGWGWDGRVKMPKLKMPSFGL-ARGKEAEVQGDRASPGEKAESTAVQLKIPEV 1099

Query: 4599 DLNLKGPKVKGDMDISLPKVEGDLKGPEVDIRDPKVDIDVPDVDVQGPDWHLKMPK--VK 4656
            +L   G + +G       + EG +    + +   KV      V  +G D  L+MP   + 
Sbjct: 1100 ELVTLGAQEEG-------RAEGAVAVSGMQLSGLKVS-TAGQVVTEGHDAGLRMPPLGIS 1151

Query: 4657 MPKFSMPGFKGE----GPDVDVNLPKADIDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMP 4712
            +P+  + GF GE    G      +P A+   +G +  V VP V +  P A++ G +  + 
Sbjct: 1152 LPQVELTGF-GEAGTPGQQAQSTVPSAE-GTAGYR--VQVPQVTLSLPGAQVAGGELLVG 1207

Query: 4713 EMSIKAPKISMPDIDLNL---------KGPKVKGDVDVTLPKVEGDLKGPEADIKGPKVD 4763
            E   K P +++P ++L++         +    +G + + LP +     G  A + G   +
Sbjct: 1208 EGVFKMPTVTVPQLELDVGLSREAQAGEAATGEGGLRLKLPTL-----GARARVGGEGAE 1262

Query: 4764 INTPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVSLPKADIDVSGPKVDVDIPDV 4823
               P  +     + L +P V++         G   +  V+  + +   +G K+ V +P  
Sbjct: 1263 EQPPGAE---RTFCLSLPDVELSPSG-----GNHAEYQVAEGEGE---AGHKLKVRLPRF 1311

Query: 4824 NI----EGPD--AKLKGPKFKMPEINIKAPKI----SIPDVDLDLKGPKVKGDFDVSVPK 4873
             +    EG +   K K PK ++P +     ++      P  + + +  +       S  +
Sbjct: 1312 GLVRAKEGAEEGEKAKSPKLRLPRVGFSQSEMVTGEGSPSPEEEEEEEEEGSGEGASGRR 1371

Query: 4874 VEGTLKGPEVDLKGPRLDFEGPD--------AKLSGPSLKMPSLEISAPKVTAPDVD--- 4922
                ++ P V L  P     G +         +   P  + P + +S PK  +   D   
Sbjct: 1372 GRVRVRLPRVGLAAPSKASRGQEGDAAPKSPVREKSPKFRFPRVSLS-PKARSGSGDQEE 1430

Query: 4923 --LHLKAPKIGFS-----GP-KLEGGE 4941
              L ++ P +GFS     GP ++EG +
Sbjct: 1431 GGLRVRLPSVGFSETGAPGPARMEGAQ 1457



 Score =  211 bits (538), Expect = 1e-53
 Identities = 378/1619 (23%), Positives = 674/1619 (41%), Gaps = 409/1619 (25%)

Query: 2998 DIRGPQVDIDVPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPK 3057
            +I+GP+  +   ++    P     + K KM    +PG  G    V  +L   D++ S PK
Sbjct: 116  EIKGPRAKVAKLNIQSLSP-----VKKKKM----VPGALG----VPADLAPVDVEFSFPK 162

Query: 3058 VDIDVPDVNIEGPEGKLKGP----KFKMPEMNIKAPKISMPDIDLNLKGP---KVKGDMD 3110
                   +  E  +G +       + ++P + ++          L    P   K K + +
Sbjct: 163  FSRLRRGLKAEAVKGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAE 222

Query: 3111 VSLPKVEGDMKVPDVDIKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISMPGFKGEGPEV 3170
            V+          P V++ GP++           P   + +P++  PK + P  +  G   
Sbjct: 223  VA---AGARFTAPQVELVGPRL-----------PGAEVGVPQVSAPKAA-PSAEAAGGFA 267

Query: 3171 DVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDLDLNLKG 3230
             ++LP   L    P          +E P   ++ P+ ++P +       ++P L+     
Sbjct: 268  -LHLPTLGLGAPAPPA--------VEAPAVGIQVPQVELPALPSLPTLPTLPCLETR--- 315

Query: 3231 PKMKGEVDVSLANVEGDLKGPALDIKGPKIDVDAPDIDIHGPDAKLKGPKLKMPDMHVNM 3290
               +G V V +         P LD+  P + VD   + + G + + +G   + P++ + M
Sbjct: 316  ---EGAVSVVV---------PTLDVAAPTVGVD---LALPGAEVEARG---EAPEVALKM 357

Query: 3291 PKISMPEIDLNLKG------SKLKGDVDVSGPKLEGDIKAPSLDIKGPEVDVSGPKLNIE 3344
            P++S P      K       +K+  +  V GP+L    + P+  +   E   + P++ +E
Sbjct: 358  PRLSFPRFGARAKEVAEAKVAKVSPEARVKGPRL----RMPTFGLSLLEPRPAAPEV-VE 412

Query: 3345 GKSKKSRFKLPKFNF--SGSKVQTPE-VDVK-GKKPDIDITGPKV------DINAPDVEV 3394
             K K    K+P      SG +V+ P+  +VK  K P++ +  PKV      ++  P+VE+
Sbjct: 413  SKLKLPTIKMPSLGIGVSGPEVKVPKGPEVKLPKAPEVKL--PKVPEAALPEVRLPEVEL 470

Query: 3395 QGKVKGSKFKMPFL-SISSPKVSMPDVELNLKSPKVKGDLDIAGPNLEGDFKGPKV-DIK 3452
                K S+ K+P +  ++ P+V +P+VEL    PKV             + K PKV ++ 
Sbjct: 471  P---KVSEMKLPKVPEMAVPEVRLPEVEL----PKVS------------EMKLPKVPEMA 511

Query: 3453 APEVNLNAPDVDVHGPDWNLKMPKMKMPKFSVSGLKAEGPDVAVDLPKGDINIEGPSMNI 3512
             PEV L  P+V +      LK+ +MK+PK          P++AV                
Sbjct: 512  VPEVRL--PEVQL------LKVSEMKLPKV---------PEMAV---------------- 538

Query: 3513 EGPDLNVEGPEGGL-KGPKFKMPDMN-IKAPKISMPDIDLNLKGPKVKGDVDISLPKLEG 3570
              P++ +  PE  L K  + K+P+++ +  P++ +P++ L  K P++K   ++ LPK+  
Sbjct: 539  --PEVRL--PEVQLPKVSEMKLPEVSEVAVPEVRLPEVQLP-KVPEMKVP-EMKLPKVP- 591

Query: 3571 DLKGPEV---DIKGPKVDINAPDVDVHGPDWHL-KMPKVKMPKFSMPGFKGEGPEVDVTL 3626
            ++K PE+   +++ PKV   A   DVH P+  L K+P++K+P+  +P         +V L
Sbjct: 592  EMKLPEMKLPEVQLPKVPEMAVP-DVHLPEVQLPKVPEMKLPEMKLP---------EVKL 641

Query: 3627 PKADIDISGPNVDVDVPDVNIEGPDAKL-KGPKFKMPEM-NIKAPKISMPDFDLNLKGPK 3684
            PK          ++ VPDV++  P+ +L K P+ K+P+M  +  P++ +P+  L    PK
Sbjct: 642  PKVP--------EMAVPDVHL--PEVQLPKVPEMKLPKMPEMAVPEVRLPEVQL----PK 687

Query: 3685 MKGDVVVSLPKVEGDLKGPEVDIKGPKVDIDTPDINIEGSEGKFKGPKFKIPEMHL-KAP 3743
            +     + LPKV      PE+ +     D+  P++ +     + K P  K+PE+ L K P
Sbjct: 688  VSE---MKLPKV------PEMAVP----DVHLPEVQLP-KVCEMKVPDMKLPEIKLPKVP 733

Query: 3744 KISMPDIDL-NLKGPKVKGDVDVSLPKMEGDL-------KGPEVDI-KGPKVDINAPDVD 3794
            ++++PD+ L  ++ PKV    ++ LP+M+          K PEV + + P+V + A   +
Sbjct: 734  EMAVPDVHLPEVQLPKVS---EIRLPEMQVPKVPDVHLPKAPEVKLPRAPEVQLKATKAE 790

Query: 3795 -VQGPDWHLKMPKVKMPKFSMP-----GFKGE-GPDVD---VNLPKADLDVSG------- 3837
              +G ++  KMPK+ MPK         G  GE G +V    V LP    +V G       
Sbjct: 791  QAEGMEFGFKMPKMTMPKLGRAESPSRGKPGEAGAEVSGKLVTLPCLQPEVDGEAHVGVP 850

Query: 3838 ----PKVDIDVPDV----------------NIEGPE--GKLKGPKFKMPEMNIKAPKISM 3875
                P V++D+P                   +EGPE    ++   F++P + I  P++  
Sbjct: 851  SLTLPSVELDLPGALGLQGQVPAAKMGKGERVEGPEVAAGVREVGFRVPSVEIVTPQLPA 910

Query: 3876 PDID---LNLKGPKVKGDMDVSLPKVEGDMQVPDLDIKGPKVDINAPDVDVRGPDWHLKM 3932
             +I+   L +   KVK     SLPK           + GPKV     + +  G    LK+
Sbjct: 911  VEIEEGRLEMIETKVKPSSKFSLPK---------FGLSGPKVA--KAEAEGAGRATKLKV 959

Query: 3933 PK--IKMPKISMPG---FKGEG-----PEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDA 3982
             K  I +PK  +      KG G     P +D+++P+  LD   P   V+V      G D 
Sbjct: 960  SKFAISLPKARVGAEAEAKGAGEAGLLPALDLSIPQLSLDAHLPSGKVEVA-----GADL 1014

Query: 3983 KLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKV 4042
            K KGP+F +P+  ++       +         V G                E++ KG   
Sbjct: 1015 KFKGPRFALPKFGVRGRDTEAAEL--------VPG--------------VAELEGKG--- 1049

Query: 4043 DIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVNLPKADIDVSGPKVDIDTPD 4102
                      G D  +KMPK+KMP F +      G E +V   +A               
Sbjct: 1050 ---------WGWDGRVKMPKLKMPSFGL----ARGKEAEVQGDRAS-------------- 1082

Query: 4103 IDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPE 4162
                       G K +   + LK P     EV+L   G + +G  + ++      L G +
Sbjct: 1083 ----------PGEKAESTAVQLKIP-----EVELVTLGAQEEGRAEGAVAVSGMQLSGLK 1127

Query: 4163 VDIKGPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGP 4222
            V   G +V  +  D  ++ P   + +P+V++  F   G  G+       +P A+   +G 
Sbjct: 1128 VSTAG-QVVTEGHDAGLRMPPLGISLPQVELTGFGEAGTPGQ--QAQSTVPSAE-GTAGY 1183

Query: 4223 KVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHL---------KGPKVKG 4273
            +V   VP V +  P A++ G +  + E   K P +++P  +L +         +    +G
Sbjct: 1184 RV--QVPQVTLSLPGAQVAGGELLVGEGVFKMPTVTVPQLELDVGLSREAQAGEAATGEG 1241

Query: 4274 DVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVD----VHGPDWHLKMPKVKMPKFSMPGF 4329
             + + LP +     G    + G   +   P  +    +  PD  L        ++ +   
Sbjct: 1242 GLRLKLPTL-----GARARVGGEGAEEQPPGAERTFCLSLPDVELSPSGGNHAEYQVAEG 1296

Query: 4330 KGE-GPDVDVTLPKADIEISGPKVDIDAPDVSIEGPDAKLKGPKFKMPEMNIKAPKISMP 4388
            +GE G  + V LP+  +        + A + + EG   K K PK ++P +     ++   
Sbjct: 1297 EGEAGHKLKVRLPRFGL--------VRAKEGAEEG--EKAKSPKLRLPRVGFSQSEM--- 1343

Query: 4389 DIDFNLKGPKVKGDVDVSLPKVEGDLKGP-----EIDIKGPSLDIDTPDVNIEGPEG--- 4440
                 + G       +    + EG  +G       + ++ P + +  P     G EG   
Sbjct: 1344 -----VTGEGSPSPEEEEEEEEEGSGEGASGRRGRVRVRLPRVGLAAPSKASRGQEGDAA 1398

Query: 4441 -----KLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKV---ESDLKGP 4491
                 + K PKF+ P +++ +PK           G + +G + V LP V   E+   GP
Sbjct: 1399 PKSPVREKSPKFRFPRVSL-SPKARSG------SGDQEEGGLRVRLPSVGFSETGAPGP 1450



 Score =  180 bits (456), Expect = 4e-44
 Identities = 336/1396 (24%), Positives = 576/1396 (41%), Gaps = 289/1396 (20%)

Query: 4671 DVDVNLPKADIDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMSIKAPKISMPDIDLNL 4730
            DV+ + PK      G K +     V       +L+ P+ ++ E++ +A    +       
Sbjct: 155  DVEFSFPKFSRLRRGLKAEAVKGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPP 214

Query: 4731 KGPKVKGDVDV----TLPKVEGDLKGPEADIKGPKVDINTPDVDVHGPDWHLKMPKVKMP 4786
            +  KV+ +V      T P+VE  L GP      P  ++  P V           PK    
Sbjct: 215  RKAKVEAEVAAGARFTAPQVE--LVGPRL----PGAEVGVPQVSA---------PKAAPS 259

Query: 4787 KFSMPGFKGEGPDVDVSLPKADIDVSGPKVDVDIPDVNIEGPDAKLKGPKFKMPEINIKA 4846
              +  GF    P + +  P A   V  P V + +P V +    +    P     E    A
Sbjct: 260  AEAAGGFALHLPTLGLGAP-APPAVEAPAVGIQVPQVELPALPSLPTLPTLPCLETREGA 318

Query: 4847 PKISIPDVDLDLKGPKVKGDFDVSVPKVEGTLKGPEVDLKGPRLDFE------------- 4893
              + +P   LD+  P V  D  +   +VE   + PEV LK PRL F              
Sbjct: 319  VSVVVPT--LDVAAPTVGVDLALPGAEVEARGEAPEVALKMPRLSFPRFGARAKEVAEAK 376

Query: 4894 ----GPDAKLSGPSLKMPS--LEISAPKVTAPD-VDLHLKAPK-------IGFSGPKL-- 4937
                 P+A++ GP L+MP+  L +  P+  AP+ V+  LK P        IG SGP++  
Sbjct: 377  VAKVSPEARVKGPRLRMPTFGLSLLEPRPAAPEVVESKLKLPTIKMPSLGIGVSGPEVKV 436

Query: 4938 -EGGEVDL-KGPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKFGFGAKSPKADIKSPS 4995
             +G EV L K P+V+ P +      P+  +  P+V++P+ + PK         +++K P 
Sbjct: 437  PKGPEVKLPKAPEVKLPKV------PEAAL--PEVRLPEVELPKV--------SEMKLPK 480

Query: 4996 L-DVTVPEAEL-NLETPEISVGGKGKKSKFKMPKIHMSGPKIKAKKQGFDLNVPGGEIDA 5053
            + ++ VPE  L  +E P++S     K  +  +P++ +  P+++  K   ++ +P      
Sbjct: 481  VPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVRL--PEVQLLKVS-EMKLP------ 531

Query: 5054 SLKAPDVDV-NIAGPDAAL-KV-DVKSPKTKKTMFGKMYFPDVEF----DIKSPKFK--- 5103
              K P++ V  +  P+  L KV ++K P+  +    ++  P+V+     ++K P+ K   
Sbjct: 532  --KVPEMAVPEVRLPEVQLPKVSEMKLPEVSEVAVPEVRLPEVQLPKVPEMKVPEMKLPK 589

Query: 5104 -AEAPLPSPKLEGELQAPDL-ELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGDLKG 5161
              E  LP  KL  E+Q P + E+++P +H+  + +  K P++K+P++ +       ++K 
Sbjct: 590  VPEMKLPEMKLP-EVQLPKVPEMAVPDVHLPEVQL-PKVPEMKLPEMKLP------EVKL 641

Query: 5162 PKVQANLGAPDINIEGLD----AKVKTPSF-GISAPQVSIPDVNV----NLKGPKI-KGD 5211
            PKV   +  PD+++  +      ++K P    ++ P+V +P+V +     +K PK+ +  
Sbjct: 642  PKV-PEMAVPDVHLPEVQLPKVPEMKLPKMPEMAVPEVRLPEVQLPKVSEMKLPKVPEMA 700

Query: 5212 VPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVH---AQLPSLEGDLRG 5268
            VP V L  P+V L     ++K P   +P+I +P V  E    +VH    QLP +  ++R 
Sbjct: 701  VPDVHL--PEVQLP-KVCEMKVPDMKLPEIKLPKVP-EMAVPDVHLPEVQLPKV-SEIRL 755

Query: 5269 PDVKL-EGPDVSL-KGPGVDLP------------------SVNLSMPKVSGPDLDLNLKG 5308
            P++++ + PDV L K P V LP                       MPK++ P L    + 
Sbjct: 756  PEMQVPKVPDVHLPKAPEVKLPRAPEVQLKATKAEQAEGMEFGFKMPKMTMPKLG-RAES 814

Query: 5309 PS--LKGDLDASVPSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVG----APD 5362
            PS    G+  A V    V  P L    V G+  VG   + +P ++      +G     P 
Sbjct: 815  PSRGKPGEAGAEVSGKLVTLPCLQ-PEVDGEAHVGVPSLTLPSVELDLPGALGLQGQVPA 873

Query: 5363 VTL-RGPSLQGDLAVSG----DIKCPKVSVGAPDL-SLEASEGSIKL--------PKMKL 5408
              + +G  ++G    +G      + P V +  P L ++E  EG +++         K  L
Sbjct: 874  AKMGKGERVEGPEVAAGVREVGFRVPSVEIVTPQLPAVEIEEGRLEMIETKVKPSSKFSL 933

Query: 5409 PQFGISTPGSDLHVNAKGPQVS-GELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGA 5467
            P+FG+S           GP+V+  E +G G    LK  +       F +  PK +  +GA
Sbjct: 934  PKFGLS-----------GPKVAKAEAEGAGRATKLKVSK-------FAISLPKAR--VGA 973

Query: 5468 TGEIKGPTVGGGLPGIGVQ----GLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEI 5523
              E KG    G LP + +      L+ +L    ++ +G D+   G    LP   + G + 
Sbjct: 974  EAEAKGAGEAGLLPALDLSIPQLSLDAHLPSGKVEVAGADLKFKGPRFALPKFGVRGRDT 1033

Query: 5524 KGG--------LKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGG 5575
            +          L+G   G+ G      +K P+F +A  +      ++G +   G      
Sbjct: 1034 EAAELVPGVAELEGKGWGWDGRVKMPKLKMPSFGLARGKE---AEVQGDRASPGEKAES- 1089

Query: 5576 VSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGG----VKGG 5631
             +A  + + E  L   G+  E +          + +    G+  SG KV        +G 
Sbjct: 1090 -TAVQLKIPEVELVTLGAQEEGRA---------EGAVAVSGMQLSGLKVSTAGQVVTEGH 1139

Query: 5632 QIGLQAPGLSVSGPQGHLESGSGKVTFP-----------------KMKIPKFTFS--GRE 5672
              GL+ P L +S PQ  L +G G+   P                 ++++P+ T S  G +
Sbjct: 1140 DAGLRMPPLGISLPQVEL-TGFGEAGTPGQQAQSTVPSAEGTAGYRVQVPQVTLSLPGAQ 1198

Query: 5673 LVGREMGV--------DVHFPKAEASI----QAGAGDGEWEESEVKLKKSKIKMPKFNFS 5720
            + G E+ V         V  P+ E  +    +A AG+    E  ++L     K+P     
Sbjct: 1199 VAGGELLVGEGVFKMPTVTVPQLELDVGLSREAQAGEAATGEGGLRL-----KLPTLGAR 1253

Query: 5721 KPKGKGGV------------TGSPEASISGSKGDLKSSKASLGSLEGEAEAEASSPKGKF 5768
               G  G                P+  +S S G+    + + G  EGEA  +      +F
Sbjct: 1254 ARVGGEGAEEQPPGAERTFCLSLPDVELSPSGGNHAEYQVAEG--EGEAGHKLKVRLPRF 1311

Query: 5769 SLF----------KSKKPRHR--SNSFSDEREFSGPSTPTGTLEFEGGEVSLEGGKVKGK 5816
             L           K+K P+ R     FS     +G  +P+   E E  E    G    G+
Sbjct: 1312 GLVRAKEGAEEGEKAKSPKLRLPRVGFSQSEMVTGEGSPSPEEEEEEEEEG-SGEGASGR 1370

Query: 5817 HGKLKFG-TFGGLGSKSKGHYEVTGS-------DDETGKLQGSGVSLASKKSRLSSSSSN 5868
             G+++      GL + SK      G         +++ K +   VSL S K+R  S    
Sbjct: 1371 RGRVRVRLPRVGLAAPSKASRGQEGDAAPKSPVREKSPKFRFPRVSL-SPKARSGSGDQE 1429

Query: 5869 DSGNKVGIQLPEVELS 5884
            + G +V  +LP V  S
Sbjct: 1430 EGGLRV--RLPSVGFS 1443



 Score = 60.8 bits (146), Expect = 4e-08
 Identities = 91/390 (23%), Positives = 149/390 (38%), Gaps = 92/390 (23%)

Query: 5187 FGISAPQVSIPDVNVNLKGP-KIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSM------- 5238
            + I  P+  +  +N+    P K K  VP  G  G   DL   + +  FPKFS        
Sbjct: 115  YEIKGPRAKVAKLNIQSLSPVKKKKMVP--GALGVPADLAPVDVEFSFPKFSRLRRGLKA 172

Query: 5239 ------------------PKIGIPGVKMEGGGAEVHAQLP-----SLEGDLRGPDVKLEG 5275
                              P++ +  V  E   A + A  P      +E ++     +   
Sbjct: 173  EAVKGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEV-AAGARFTA 231

Query: 5276 PDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLSG-V 5334
            P V L GP   LP   + +P+VS P        PS +     +     +H P L L    
Sbjct: 232  PQVELVGP--RLPGAEVGVPQVSAPK-----AAPSAE-----AAGGFALHLPTLGLGAPA 279

Query: 5335 GGKMQVGGDGVKVPGIDATT------------------KLNVGAPDVTLRGPSLQGDLAV 5376
               ++    G++VP ++                      ++V  P + +  P++  DLA+
Sbjct: 280  PPAVEAPAVGIQVPQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLAL 339

Query: 5377 SGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGP 5436
             G            +   EA E ++K+P++  P+FG           AK  +VS E +  
Sbjct: 340  PG---------AEVEARGEAPEVALKMPRLSFPRFGARAKEV---AEAKVAKVSPEAR-- 385

Query: 5437 GVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPG 5496
                 +KGPR+  P    +L  P+         ++K PT+     GIGV G E  +++P 
Sbjct: 386  -----VKGPRLRMPTFGLSLLEPRPAAPEVVESKLKLPTIKMPSLGIGVSGPE--VKVP- 437

Query: 5497 IKSSGCDVNLP-GVNVKLP-TGQISGPEIK 5524
                G +V LP    VKLP   + + PE++
Sbjct: 438  ---KGPEVKLPKAPEVKLPKVPEAALPEVR 464


>gi|55769541 AHNAK nucleoprotein isoform 2 [Homo sapiens]
          Length = 149

 Score =  234 bits (596), Expect = 2e-60
 Identities = 114/115 (99%), Positives = 115/115 (100%)

Query: 1   MEKEETTRELLLPNWQGSGSHGLTIAQRDDGVFVQEVTQNSPAARTGVVKEGDQIVGATI 60
           MEKEETTRELLLPNWQGSGSHGLTIAQRDDGVFVQEVTQNSPAARTGVVKEGDQIVGATI
Sbjct: 1   MEKEETTRELLLPNWQGSGSHGLTIAQRDDGVFVQEVTQNSPAARTGVVKEGDQIVGATI 60

Query: 61  YFDNLQSGEVTQLLNTMGHHTVGLKLHRKGDRSPEPGQTWTREVFSSCSSEVVLS 115
           YFDNLQSGEVTQLLNTMGHHTVGLKLHRKGDRSPEPGQTWTREVFSSCSSEVVL+
Sbjct: 61  YFDNLQSGEVTQLLNTMGHHTVGLKLHRKGDRSPEPGQTWTREVFSSCSSEVVLN 115


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 94.4 bits (233), Expect = 3e-18
 Identities = 309/1283 (24%), Positives = 512/1283 (39%), Gaps = 208/1283 (16%)

Query: 1056  KMPEMHFRAPKMSLPDVDLDLKGPKMKGNVDISAPKIEGEMQVPDVDIRGPKVDIKAPDV 1115
             K+PE+    P+  +P+    +  PK K       P++  + +         KV +  P  
Sbjct: 9949  KVPEV----PRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPE--------EKVPVLIPKK 9996

Query: 1116  EGQGLDWSLKIPKMKMPKFSMP---SLKGEGPEVDV-NLPKADVVVSGPKVDIEAPDVSL 1171
             E        ++PK  +P+  +P     K E P   V  +PK  V     KV + AP   +
Sbjct: 9997  EKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEK--KVPVPAPK-KV 10053

Query: 1172  EGPEGKL-KGPKFKMPEMHFKTP---KISMPDVDLHLKGPKVKGDVDVSVPKVEG----E 1223
             E P  K+ + PK  +PE    TP   K+  P   +  K   V   V V++P+ E     E
Sbjct: 10054 EAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVP--VPVALPQEEEVLFEE 10111

Query: 1224  MKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMP--KFSMPGFKGEGREVDVNLPKA 1281
               VP+ E+   + ++   + EV   +  +   + ++P  +  +P  +    E +  +P+ 
Sbjct: 10112 EIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEE 10171

Query: 1282  DI--DVSGPKVDVE--VPDVSLEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLNLKG--- 1334
             ++  +V  PKV V   VP++  +  E K+  PK +      +AP   +P+V   ++    
Sbjct: 10172 EVLPEVK-PKVPVPAPVPEIKKKVTEKKVVIPKKE------EAPPAKVPEVPKKVEEKRI 10224

Query: 1335  --PKLKGDVDVSLPEVEGEMKVPDVDIKGPKVDISAPDVDVHGPDWHLKMPKVKMPKFSM 1392
               PK +  + V + E   E  + + +I  P+   S  +V+   P    ++ K  +P+   
Sbjct: 10225 ILPKEEEVLPVEVTEEPEEEPISEEEI--PEEPPSIEEVEEVAPPRVPEVIKKAVPEAPT 10282

Query: 1393  PGFKGEGPEVDVKLPKADVDVSGPKMDAEVPDVNIEGPDAKLKGPKFKMPEMSI-KPQKI 1451
             P  K       V+ P A V    P+    VP    E P AK+     K+PE  +  P+K 
Sbjct: 10283 PVPK------KVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKE 10336

Query: 1452  SIPDV-GLHLKGPKMKGDY--DVTVPK------VEGEIKAPDVDIKGPKVDINAPDVEVH 1502
             ++P   G  +   K+   +  +V V +      VE E++    + +  +V+    + E H
Sbjct: 10337 AVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFH 10396

Query: 1503  GPDWHLKMP--------KVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPDVN 1554
               +  +K+         +V+     +  F+ E  EV    PKA     GP++   +  + 
Sbjct: 10397 EVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEV-FEKPKAP--PKGPEISEKI--IP 10451

Query: 1555  LEAPEGKL---KGPKFKMPSMN---IQTHKISMPDVGLNLKAPKL-KTDVDVSLPKVEGD 1607
              + P  K+   K P  K+P +    +   K+ +P+       P++  T V   LP  E  
Sbjct: 10452 PKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPE------EPRVPPTKVPEVLPPKE-- 10503

Query: 1608  LKGPEIDVKAPKMDVNVGDIDIEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKV 1667
                PE  V  P             P  K + P  K+PE    APK  +P+  + +  PK 
Sbjct: 10504 -VVPEKKVPVP-------------PAKKPEAPPPKVPE----APKEVVPEKKVPVPPPKK 10545

Query: 1668  KGDMDVSVPKVE----GEMKVPDVDIKGPKVDIDAPDVEVHDPDWHLKMPKMKMPKFSMP 1723
                    VP+V      E KVP+     PK +   P+V         + PK  +P+  +P
Sbjct: 10546 PEVPPTKVPEVPKAAVPEKKVPEA--IPPKPESPPPEVP--------EAPKEVVPEKKVP 10595

Query: 1724  GFKAEGPEV-DVNLPKADIDVSGPSVDTDAPDLDIEGPEGKLKG------SKFKMPKLNI 1776
                 + PEV  V +P+A  +V         P    E P  K+         + K+P+   
Sbjct: 10596 AAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIP 10655

Query: 1777  KAPKVSMPDVDLNLKGPKLKGEIDASVPELEGDLRGPQVDV--KGPFVEAEVPDVDLECP 1834
               P+   P+V    +   L+ E  A V E       PQV V  K P  E + P V  + P
Sbjct: 10656 PKPESPPPEVFEEPEEVALE-EPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKP 10714

Query: 1835  DAKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDADVSVPKLEGDLTGPSVGVEVP 1894
             +     P  K+PE+    PK  +P+  + L  PK        VP++  ++  P   V VP
Sbjct: 10715 EL----PPVKVPEV----PKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVV-PEKKVAVP 10765

Query: 1895  DVELECPDAKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDVDVSVPKLEGDLTGP 1954
               + E P AK+  P+     +  + P + +P+       P+V  + +   P+ E     P
Sbjct: 10766 K-KPEVPPAKV--PEVPKKPVLEEKPAVPVPE-RAESPPPEVYEEPEEIAPEEE---IAP 10818

Query: 1955  SVGVEVPDVELECPD----AKLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVKGDMDVS 2010
                  VP  E E P+    A  + PK  +PE   K P I  P+       PK        
Sbjct: 10819 EEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEK--KVPVIKKPEA----PPPK-------- 10864

Query: 2011  VPKVEGEMKVPDVDIKGPKMDIDAPDVDVHGPDWHLK-MPKMKMP-------KFSMPGFK 2062
              P+ E  ++ P +  + P      P  DV    + LK +PK K+P       K  +   K
Sbjct: 10865 EPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLK 10924

Query: 2063  AEGPEVDVN--LPKADVVVSGPKVDVEVPDVSLEGPEGKLKGPKLKMPEMHFKAPKISMP 2120
               G E  V   LP+       PK +V +  V  + PE   + PK++ P+   K  K ++P
Sbjct: 10925 VPGGEKKVRKLLPERK---PEPKEEVVLKSVLRKRPEE--EEPKVE-PKKLEKVKKPAVP 10978

Query: 2121  DVDLHLKGPKVKGDVDV-SLPKLEGDLTGPSVDVEV-PDVELECPDAKLKGPKFKMPEMH 2178
             +       PK   +V+V ++ K E  +  P+   E+ P + L  P+ K K      PE  
Sbjct: 10979 EP----PPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPK------PEAE 11028

Query: 2179  FKTPKISMPDVNLNLKGPKVKGDMDVSVPKVEGEMKVPDVDIRGPKVDIDAPDVDVHGPD 2238
              KT  I  P V    +   +   + V V   + E K P  +   PK  I         P 
Sbjct: 11029 VKT--IKPPPV--EPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSP- 11083

Query: 2239  WHLKMPKMKMPKFSMPGFKGEGP 2261
               ++  + K+     PG  GE P
Sbjct: 11084 --IEAERRKL----RPGSGGEKP 11100



 Score = 90.5 bits (223), Expect = 4e-17
 Identities = 286/1261 (22%), Positives = 509/1261 (40%), Gaps = 188/1261 (14%)

Query: 1887  PSVGVEVPDVELE-CPDAKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDVDVSVP 1945
             P + V+VP+V  +  P+ K   P  K  +    AP   +P+V    K P+ K  V V +P
Sbjct: 9944  PVIPVKVPEVPRKPVPEEKKPVPVPKKKE----APPAKVPEVP---KKPEEK--VPVLIP 9994

Query: 1946  KLEGDLTG--PSVGVE-VPDVELECP-DAKLKGPKFKMPEMHFKTPKISMPDVDLHLKGP 2001
             K E       P V  + VP+ ++  P   K++ P  K+PE+    PK  +P+  + +  P
Sbjct: 9995  KKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEV----PKKPVPEKKVPVPAP 10050

Query: 2002  KVKGDMDVSVPKVEGEMKVPDVDIKGP-KMDIDAPDVDVHGPDWHLKMPKMKMPKFSMPG 2060
             K        VP+V  ++ +P+     P    ++AP   V      + +P + +P+     
Sbjct: 10051 KKVEAPPAKVPEVPKKL-IPEEKKPTPVPKKVEAPPPKVPKKREPVPVP-VALPQEEEVL 10108

Query: 2061  FKAE-GPEVDVNLPKADVVVSGPKVDVEVPDVSLEGPEGKLKGPKLKMPEMHFKAPKISM 2119
             F+ E  PE +V   + +V+    +V  E  +V  E  E   +  ++   E +    +  +
Sbjct: 10109 FEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFV 10168

Query: 2120  PDVDLHLKGPKVKGDVDVSLPKLEGDLTGPSVDVEVPDVELECPDAKLKGPKFKMPEMHF 2179
             P+ ++    P+VK  V V  P        P +  +V + ++  P  K + P  K+PE+  
Sbjct: 10169 PEEEVL---PEVKPKVPVPAPV-------PEIKKKVTEKKVVIPK-KEEAPPAKVPEV-- 10215

Query: 2180  KTPKISMPDVNLNLKGPKVKGDMDVSVPKVEGEMKVPDVDIRGPKVDIDAPDVDVHGPDW 2239
                K+    + L    PK +  + V V +   E  + + +I  P+      +V+   P  
Sbjct: 10216 -PKKVEEKRIIL----PKEEEVLPVEVTEEPEEEPISEEEI--PEEPPSIEEVEEVAPP- 10267

Query: 2240  HLKMPKMKMPKFSMPGFKGEGPEVDVNLPKADVDVSGPKVDVEVPDVSLEGPEGKLKGPK 2299
               ++P++          K   PE    +PK  V+    KV  ++P+  +  P  K + P 
Sbjct: 10268 --RVPEV---------IKKAVPEAPTPVPKK-VEAPPAKVSKKIPEEKVPVPVQKKEAPP 10315

Query: 2300  FKMPEMHFKTP--KISMPDVDFNLKGPKIKGDVDVSAPKLEGELKGPELDVKGPKLDADM 2357
              K+PE+  K P  K+ +P  +     P  KG   V   K+    +  E+ VK  +L+ ++
Sbjct: 10316 AKVPEVPKKVPEKKVLVPKKE---AVPPAKGRT-VLEEKVSVAFR-QEVVVK-ERLELEV 10369

Query: 2358  PEVAVEGPNGKWKTPKFKMPDMHFKAPKISMPDLDLHLKSPKAKGEVDVD-VPKLEGDLK 2416
              E  VE      +  +F   + +F+  +    +  + L+  + + E  V+ V ++    +
Sbjct: 10370 VEAEVEEIP---EEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFE 10426

Query: 2417  GPHVDVSGPDIDIEGPEGKLKGPKFKMPDMHFKAPNISMPDVDLNLKGPKIKGDVDVSVP 2476
                V+V       E P+   KGP+     +  K P    P   +  K P  K      VP
Sbjct: 10427 AEEVEV------FEKPKAPPKGPEISEKIIPPKKP----PTKVVPRKEPPAK------VP 10470

Query: 2477  EVEGKLEVPDMNIRGPKVDVNAPDVQAPDWHLKMPKMKMPKFSMPGFKAEGPEVDV-NLP 2535
             EV  K+ V +  +R P+ +   P  + P+  +  PK  +P+  +P   A+ PE     +P
Sbjct: 10471 EVPKKIVVEE-KVRVPE-EPRVPPTKVPE--VLPPKEVVPEKKVPVPPAKKPEAPPPKVP 10526

Query: 2536  KADVDISGPKVDIEGPDVNIEGPEGKL-KGPKLKMPEMNI----------------KAPK 2578
             +A  ++   K     P    E P  K+ + PK  +PE  +                +APK
Sbjct: 10527 EAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPK 10586

Query: 2579  ISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKM 2638
               +P+  +    PK      V +P+       P+  +   KV +  P      P    ++
Sbjct: 10587 EVVPEKKVPAAPPKKPEVTPVKVPEA------PKEVVPEKKVPVPPPKKPEVPPTKVPEV 10640

Query: 2639  PKVKMPKFSMPGF---KGEGPDGDVKLPKADIDVSGPKVDI-------EGPDVNIEG--- 2685
             PKV +P+  +P     K E P  +V     ++ +  P  ++         P V +     
Sbjct: 10641 PKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKP 10700

Query: 2686  -PEGKLKGPKFKMPEMN-IKAPKIS---MPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPE 2740
              PE K      K PE+  +K P++    +P+  + L  PK        +P+V  ++  PE
Sbjct: 10701 VPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVV-PE 10759

Query: 2741  VDIKGPKVDIDAPDVDVHGPDWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKADI---DV 2797
               +  PK   + P   V  P+   K    + P + +P  + E P  +V     +I   + 
Sbjct: 10760 KKVAVPKKP-EVPPAKV--PEVPKKPVLEEKPAVPVPE-RAESPPPEVYEEPEEIAPEEE 10815

Query: 2798  SGPKVDVECPDVNIEGPE----GKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDV 2853
               P+ +   P    E PE       + PK  +PE   K P I  P+       PK     
Sbjct: 10816 IAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEK--KVPVIKKPEAP----PPK----- 10864

Query: 2854  DVTGPKVEGDLKGPEVDLKGPKVDIDVPDVNVQGPDWHLK-MPKMKMP-------KFSMP 2905
                 P+ E  ++ P++  + P      P  +V+   + LK +PK K+P       K  + 
Sbjct: 10865 ---EPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELT 10921

Query: 2906  GFKAEGPEVDVN--LPKADVDVSGPKVDVEGPDVNIEGPEGKLKGPKFKMPEMN-IKAPK 2962
               K  G E  V   LP+   +   PK +V    V  + PE +   PK +  ++  +K P 
Sbjct: 10922 PLKVPGGEKKVRKLLPERKPE---PKEEVVLKSVLRKRPEEE--EPKVEPKKLEKVKKPA 10976

Query: 2963  IPMPDFDLHLKGPKVKGDVDISLPKV-EGDLKGPEVDIRGPQVDIDVPDVGVQGPDWHLK 3021
             +P P        P  K   ++ +P V + + K PE   + P++    P + +  P+   K
Sbjct: 10977 VPEP--------PPPKPVEEVEVPTVTKRERKIPE-PTKVPEIK---PAIPLPAPEPKPK 11024

Query: 3022  MPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKM 3081
              P+ ++     P  + E   +   +    + V G K +   P      P+G +KG   K 
Sbjct: 11025 -PEAEVKTIKPPPVEPEPTPIAAPVT---VPVVGKKAEAKAPKEEAAKPKGPIKGVPKKT 11080

Query: 3082  P 3082
             P
Sbjct: 11081 P 11081



 Score = 89.4 bits (220), Expect = 1e-16
 Identities = 295/1265 (23%), Positives = 498/1265 (39%), Gaps = 215/1265 (16%)

Query: 581   PKVKGGVDVTLPRVEGKVKVPEVDVRGP-KVDVSAPDVEAHGPEWNLKMPKMKMPTFSTP 639
             P+ K  V V   +     KVPEV  +   KV V  P  E   P    ++PK  +P    P
Sbjct: 9959  PEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVP 10018

Query: 640   ---GAKGEGPDVHMT------LPKGDISISGPKVNVEAPDVNLEGLGGKL---------- 680
                  K E P   +       +P+  + +  PK  VEAP   +  +  KL          
Sbjct: 10019 VPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPK-KVEAPPAKVPEVPKKLIPEEKKPTPV 10077

Query: 681   ----KGPDVKLPDMSVKTP-KISMPDVDLHVKGTKVKGEYDVTVPKLEGELKGPKVDIDA 735
                 + P  K+P      P  +++P  +  +   ++  E +V +P+ E  L  P+ +   
Sbjct: 10078 PKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEV-LPEEEEVL--PEEEEVL 10134

Query: 736   PDVDVHGPDWHLKMPKMKMPKFSVPGFKAEGPEVDVNLPKADV--DISGPKIDVTAPDVS 793
             P+ +   P+     P+ +     VP  +   PE +  +P+ +V  ++  PK+ V AP   
Sbjct: 10135 PEEEEVLPEEEEIPPEEE----EVPPEEEYVPEEEEFVPEEEVLPEVK-PKVPVPAP--- 10186

Query: 794   IEEPEGKLKGPKFKMPEMNIKVPKISMPDVDLHLKGPNVKGEYDVTMPKVESEIKV---- 849
             + E + K+   K  +P+   + P   +P+V      P    E  + +PK E  + V    
Sbjct: 10187 VPEIKKKVTEKKVVIPKKE-EAPPAKVPEV------PKKVEEKRIILPKEEEVLPVEVTE 10239

Query: 850   -----PDVELKSAKMDIDVPDVEVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKA 904
                  P  E +  +    + +VE   P    ++ K  +P+   P  K       V  P A
Sbjct: 10240 EPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKK------VEAPPA 10293

Query: 905   DVDISGPKVGVEVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGPKVKGEY 964
              V    P+  V VP    E P  K+     K+PE  +  PK    +     KG  V  E 
Sbjct: 10294 KVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPK---KEAVPPAKGRTVLEEK 10350

Query: 965   DMTVPKLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGPEFDVNLSK 1024
                  + E  +K  ++++   + E++      +  +++  ++       E  EF + L +
Sbjct: 10351 VSVAFRQEVVVK-ERLELEVVEAEVEEIPEEEEFHEVE--EYFEEGEFHEVEEF-IKLEQ 10406

Query: 1025  ANVDISAPKVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKGPKMKGN 1084
               V+        +      E  E ++    F+ P+   + P++S  +  +  K P  K  
Sbjct: 10407 HRVEEEHRVEKVHRVIEVFEAEEVEV----FEKPKAPPKGPEIS--EKIIPPKKPPTK-- 10458

Query: 1085  VDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLKGEGP 1144
                  P+ E   +VP+V    PK  +    V    +    ++P  K+P+   P  K   P
Sbjct: 10459 ---VVPRKEPPAKVPEV----PKKIVVEEKVR---VPEEPRVPPTKVPEVLPP--KEVVP 10506

Query: 1145  EVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDLHL 1204
             E  V +P A    + P    EAP   +  PE K+  P  K PE+    P   +P+V    
Sbjct: 10507 EKKVPVPPAKKPEAPPPKVPEAPKEVV--PEKKVPVPPPKKPEV----PPTKVPEV---- 10556

Query: 1205  KGPKVKGDVDVSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMPKFSM 1264
               PK       +VP    E KVP  E   PK +   P+V         + PK  +P+  +
Sbjct: 10557 --PK------AAVP----EKKVP--EAIPPKPESPPPEVP--------EAPKEVVPEKKV 10594

Query: 1265  PGFKGEGREV-DVNLPKADIDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKAPKI 1323
             P    +  EV  V +P+A  +V  P+  V VP      P  K + P  K+PE+    PK+
Sbjct: 10595 PAAPPKKPEVTPVKVPEAPKEVV-PEKKVPVP------PPKKPEVPPTKVPEV----PKV 10643

Query: 1324  SMPDVDLNLKGPK-LKGDVDVSLPEVEGEMKVPDVDIKGPKVDISAPDVDVHGPDWHLKM 1382
             ++P+     K P+ +    +   PEV  E +  +V ++ P  ++   + +   P      
Sbjct: 10644 AVPE----KKVPEAIPPKPESPPPEVFEEPE--EVALEEPPAEV-VEEPEPAAPPQVTVP 10696

Query: 1383  PKVKMPKFSMPGFKGEGPEV-DVKLPKADVDVSGPKMDAEVPDVNIEGPDAKL-KGPKFK 1440
             PK  +P+   P    + PE+  VK+P+   +V   K    V     E P AK+ + PK  
Sbjct: 10697 PKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEV 10756

Query: 1441  MPEMSIK-PQKISIPDVGLH--LKGPKMKGDYDVTVPK----------VEGEIKAPDVDI 1487
             +PE  +  P+K  +P   +    K P ++    V VP+           E E  AP+ +I
Sbjct: 10757 VPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEI 10816

Query: 1488  KGPKVDINAPDVEVHGPDW--------------HLKMPKVKMPKFSMPGFKGEGPEVDMN 1533
               P+ +   P  E   P+                 K+P +K P+   P    + PE +  
Sbjct: 10817 -APEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPP----KEPEPEKV 10871

Query: 1534  LPKADLGVSGPKVDIDVPDVNLEAPEGKLKG-PKFKMPSMNIQTHKISMPDVGLNLKAPK 1592
             + K  L    P      P  +++    +LK  PK K+P       K+ +      LK P 
Sbjct: 10872 IEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTP----LKVPG 10927

Query: 1593  LKTDVDVSLPKVEGDLKGPEIDVKAPKMDVNVGDIDIEGPEGKLKGPKFKMPEMHFKAPK 1652
              +  V   LP+     + PE     PK +V +  +  + PE   + PK + P+   K  K
Sbjct: 10928 GEKKVRKLLPE-----RKPE-----PKEEVVLKSVLRKRPEE--EEPKVE-PKKLEKVKK 10974

Query: 1653  ISMPDVDLHLKGPKVKGDMDVSVPKV-EGEMKVPD----VDIKGPKVDIDAPDVEVHDPD 1707
              ++P+       P  K   +V VP V + E K+P+     +IK P + + AP+ +   P 
Sbjct: 10975 PAVPE------PPPPKPVEEVEVPTVTKRERKIPEPTKVPEIK-PAIPLPAPEPK---PK 11024

Query: 1708  WHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADIDVSGPSVDTDAPDLDIEGPEGKLKGS 1767
                ++  +K P           PE         + V G   +  AP  +   P+G +KG 
Sbjct: 11025 PEAEVKTIKPPPVE--------PEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGV 11076

Query: 1768  KFKMP 1772
               K P
Sbjct: 11077 PKKTP 11081



 Score = 88.6 bits (218), Expect = 2e-16
 Identities = 290/1239 (23%), Positives = 492/1239 (39%), Gaps = 167/1239 (13%)

Query: 4119  MPDLHLKAPKISMPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPEVDIKGP-KVDIDVPDV 4177
             +P + +K P++    V      P+ K  V V   K     K PEV  K   KV + +P  
Sbjct: 9943  VPVIPVKVPEVPRKPV------PEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKK 9996

Query: 4178  DVQGPDWHLKMPKVKMPKFSMP---GFKGEGPDVDV-NLPKADLDVSGPKVDIDVPDVNI 4233
             +   P    ++PK  +P+  +P     K E P   V  +PK    V   KV +  P   +
Sbjct: 9997  EKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKP--VPEKKVPVPAPK-KV 10053

Query: 4234  EGPDAKL-KGPKFKMPEMNIKAP---KISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGP 4289
             E P AK+ + PK  +PE     P   K+  P   +  K   V   V V+LP+ E  L   
Sbjct: 10054 EAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVP--VPVALPQEEEVLFEE 10111

Query: 4290  EVDIKG---PKVDIDAPDVDVHGPDWHLKMPK---VKMPKFSMPGFKGEGPDVDVTLPKA 4343
             E+  +    P+ +   P+ +   P+    +P+   +   +  +P  +   P+ +  +P+ 
Sbjct: 10112 EIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEE 10171

Query: 4344  DI--EISGPKVDIDAPDVSIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDFNLKGPKVKG 4401
             ++  E+  PKV + AP   I+    K+   K  +P+   +AP   +P++      PK   
Sbjct: 10172 EVLPEVK-PKVPVPAPVPEIK---KKVTEKKVVIPKKE-EAPPAKVPEV------PKKVE 10220

Query: 4402  DVDVSLPKVEGDLKGPEIDIKGPSLDIDTPDVNIEGP---EGKLKGPKFKMPEMNIKA-P 4457
             +  + LPK E ++   E+  +     I   ++  E P   E +   P  ++PE+  KA P
Sbjct: 10221 EKRIILPKEE-EVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPP-RVPEVIKKAVP 10278

Query: 4458  KISMPDFDLHLKGPKVKGDVDVSLPKVESDLKGPEVDIEGPEGKLKGPKFKMPDVHFKSP 4517
             +   P        PK      V  P  +   K PE  +  P  K + P  K+P+V  K P
Sbjct: 10279 EAPTPV-------PK-----KVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVP 10326

Query: 4518  QISMSDIDLNLKGPKIKG----DMDISVPKLEGDLKGPKVDVKGPKVGIDT--PDIDIHG 4571
             +  +  +      P  KG    +  +SV   +  +   +++++  +  ++    + + H 
Sbjct: 10327 EKKVL-VPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHE 10385

Query: 4572  PEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKVKGDMDIS----LPKVEGDLKGPEV 4627
              E   +  +F   +  +K  +  + E     K  +V    +        K +   KGPE+
Sbjct: 10386 VEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEI 10445

Query: 4628  D--IRDPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADIDVSG 4685
                I  PK     P   V   +   K+P+V  PK  +   K   P+ +  +P   +    
Sbjct: 10446 SEKIIPPKKP---PTKVVPRKEPPAKVPEV--PKKIVVEEKVRVPE-EPRVPPTKVPEVL 10499

Query: 4686  PKVDVDVPDVNIEGPDAKL-KGPKFKMPEMSIKAPKISMPDIDLNLKGPKVKGDVDVTLP 4744
             P  +V VP+  +  P AK  + P  K+PE    APK  +P+  + +  PK        +P
Sbjct: 10500 PPKEV-VPEKKVPVPPAKKPEAPPPKVPE----APKEVVPEKKVPVPPPKKPEVPPTKVP 10554

Query: 4745  KVEGDLKGPEADIKGPKVDINTPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVD-VS 4803
             +V      P+A +   KV    P      P    + PK  +P+  +P    + P+V  V 
Sbjct: 10555 EV------PKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVK 10608

Query: 4804  LPKADIDVSGPKVDVDIPDVNIEGPDAKLKGPKFKMPEINIKAPKISIPDVDLDLKGPKV 4863
             +P+A  +V  P+  V +P      P  K + P  K+PE+    PK+++P+  +    P  
Sbjct: 10609 VPEAPKEVV-PEKKVPVP------PPKKPEVPPTKVPEV----PKVAVPEKKVPEAIP-- 10655

Query: 4864  KGDFDVSVPKVEGTLKGPEVDLKGPRLDFEGPDAKL-SGPSLKMPSLEISAPKVTAPDVD 4922
                     PK E     PEV  +   +  E P A++   P    P      PK   P+  
Sbjct: 10656 --------PKPESP--PPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEK- 10704

Query: 4923  LHLKAPKIGFSGPKLEGGEVDLKGPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKFGF 4982
                KAP +    P+L   +V  + PK   P   V +  P    E P  K+P+   PK   
Sbjct: 10705 ---KAPAVVAKKPELPPVKVP-EVPKEVVPEKKVPLVVPK-KPEAPPAKVPEV--PKEVV 10757

Query: 4983  GAKS---PKADIKSPSLDVTVPEAELNLETPEISVGGKGKKSKFKMPKIHMSGPKIKAKK 5039
               K    PK     P+    VP+  +  E P + V    ++++   P+++    +I  ++
Sbjct: 10758 PEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVP---ERAESPPPEVYEEPEEIAPEE 10814

Query: 5040  Q---GFDLNVPGGEIDASLKAPDVDVNIAGPDAALKV--DVKSPKTKKTMFGKMYFPDVE 5094
             +     +  VP  E +     P      A P+   K+  + K P  KK        P+ E
Sbjct: 10815 EIAPEEEKPVPVAEEEEPEVPPP-----AVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPE 10869

Query: 5095  FDIKSPKFKAEAPLPSPKLEGELQAPDLELSLPAIHVEGLDIKAKAPK------VKMPDV 5148
               I+ PK K   P P P    E    +    L AI  + +  K + P+      +K+P  
Sbjct: 10870 KVIEKPKLKPRPPPPPPAPPKE-DVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGG 10928

Query: 5149  DISVPKIEGDLK-GPKVQANLGA----------PDINIEGLDAKVKTPSFGISAP----- 5192
             +  V K+  + K  PK +  L +          P +  + L+ KVK P+     P     
Sbjct: 10929 EKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLE-KVKKPAVPEPPPPKPVE 10987

Query: 5193  QVSIPDVNVNLKGPKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGG- 5251
             +V +P V    +       VP +    P + L  PE K K P+  +  I  P V+ E   
Sbjct: 10988 EVEVPTVTKRERKIPEPTKVPEI---KPAIPLPAPEPKPK-PEAEVKTIKPPPVEPEPTP 11043

Query: 5252  -GAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPS 5289
               A V   +   + + + P  +   P   +KG     PS
Sbjct: 11044 IAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPS 11082



 Score = 84.3 bits (207), Expect = 3e-15
 Identities = 321/1466 (21%), Positives = 571/1466 (38%), Gaps = 222/1466 (15%)

Query: 1541  VSGPKVDIDVPDVNLEAPEGKLKGPKFKMPSMNIQTHKISMPDVGLNLKAPKLKTDVDVS 1600
             ++ P+  I V  V  E    K K P  K+    +   K+ +P +   LK P  K   +  
Sbjct: 9786  ITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVP-IPKKLKPPPPKVPEE-- 9842

Query: 1601  LPKVEGDLKGPEIDVKAPKMDVNVGDIDIE-GPEGKLKGPKFKMPEMHFKAPKISMPDVD 1659
              PK   + K      K  K  V      +   P+  +   K  +P     AP + +P+V 
Sbjct: 9843  -PKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEV-APPVRVPEVP 9900

Query: 1660  LHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKVDIDAPDVEVHDPDWHLKMPKMKMPK 1719
               L+  +V  + +V     E  ++  +  I   +  I   +V    P    ++P+  +P+
Sbjct: 9901  KELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPE 9960

Query: 1720  FSMP---GFKAEGPEVDV----NLPKADIDVSGPSVDTDAPDLDIEGPEGKLKGSKFKMP 1772
                P     K E P   V      P+  + V  P  +   P    E P+  +   K  +P
Sbjct: 9961  EKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVP 10020

Query: 1773  -KLNIKAPKVSMPDVDLNLKGPKLKGEIDASVPELEGDLRGPQVDVKGPFVEAEVPDVDL 1831
                 ++AP   +P+V      PK        VPE +  +  P+  V+ P   A+VP+V  
Sbjct: 10021 VPKKVEAPPAKVPEV------PK------KPVPEKKVPVPAPK-KVEAP--PAKVPEVPK 10065

Query: 1832  EC-PDAK--------LKGPKFKMPEMHFKAP-KISMPDVDLHLKGPKVKGDADVSVPKLE 1881
             +  P+ K        ++ P  K+P+     P  +++P  +  L   ++  + +V +P+ E
Sbjct: 10066 KLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEV-LPEEE 10124

Query: 1882  GDLTGPSVGVEVPDVELECPDAKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDVD 1941
               L  P     +P+ E   P+ +   P+    +      +  +P+ +  +   +V  +V 
Sbjct: 10125 EVL--PEEEEVLPEEEEVLPEEEEIPPE----EEEVPPEEEYVPEEEEFVPEEEVLPEVK 10178

Query: 1942  VSVPKLEGDLTGPSVGVEVPDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVDLHLKGP 2001
               VP          V   VP+++ +  + K+  PK K      K P++     +  +  P
Sbjct: 10179 PKVP----------VPAPVPEIKKKVTEKKVVIPK-KEEAPPAKVPEVPKKVEEKRIILP 10227

Query: 2002  KVKGDMDVSVPKVEGEMKVPDVDIKGPKMDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGF 2061
             K +  + V V +   E  + + +I  P+      +V+   P    ++P++          
Sbjct: 10228 KEEEVLPVEVTEEPEEEPISEEEI--PEEPPSIEEVEEVAPP---RVPEV---------I 10273

Query: 2062  KAEGPEVDVNLPKADVVVSGPKVDVEVPDVSLEGPEGKLKGPKLKMPEMHFKAP--KISM 2119
             K   PE    +PK  V     KV  ++P+  +  P  K + P  K+PE+  K P  K+ +
Sbjct: 10274 KKAVPEAPTPVPKK-VEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLV 10332

Query: 2120  PDVDLHLKGPKVKG----DVDVSLPKLEGDLTGPSVDVEVPDVELE-CPDAKLKGPKFKM 2174
             P  +     P  KG    +  VS+   +  +    +++EV + E+E  P+ +    +F  
Sbjct: 10333 PKKEAV---PPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEE----EFHE 10385

Query: 2175  PEMHFKTPKISMPDVNLNLKGPKVKGDMDVS-VPKVEGEMKVPDVDIRGPKVDIDAPDVD 2233
              E +F+  +    +  + L+  +V+ +  V  V +V    +  +V++       + P   
Sbjct: 10386 VEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEV------FEKPKAP 10439

Query: 2234  VHGPDWHLKM-PKMKMPKFSMPGFKGEGPEVDVNLPKADVDVSGPKVDVEVPDVSLEGPE 2292
               GP+   K+ P  K P   +P  + E P     +PK  V     +V  E      + PE
Sbjct: 10440 PKGPEISEKIIPPKKPPTKVVP--RKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPE 10497

Query: 2293  GKLKGPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVDVSAPKLEGELKGPELDVKGPK 2352
               +  PK  +PE     P    P+       PK+        P+ +  +  P+     P 
Sbjct: 10498 --VLPPKEVVPEKKVPVPPAKKPEAP----PPKVPEAPKEVVPEKKVPVPPPKKPEVPPT 10551

Query: 2353  LDADMPEVAV------EGPNGKWKTPKFKMPDMHFKAPKISMPDLDLHLKSPKAKGEVDV 2406
                ++P+ AV      E    K ++P  ++P+    APK  +P+  +    PK      V
Sbjct: 10552 KVPEVPKAAVPEKKVPEAIPPKPESPPPEVPE----APKEVVPEKKVPAAPPKKPEVTPV 10607

Query: 2407  DVPKLEGDLKGPHVDVSGPDIDIEGPEGKLKGPKFKMPDMHFKAPNISMPDVDLNLKGPK 2466
              VP+   ++  P   V  P      P  K + P  K+P++    P +++P+     K P+
Sbjct: 10608 KVPEAPKEVV-PEKKVPVP------PPKKPEVPPTKVPEV----PKVAVPEK----KVPE 10652

Query: 2467  -IKGDVDVSVPEV-----EGKLEVPDMNIRGPKVDVNAPDVQAPDWHLKMPKMKMPKFSM 2520
              I    +   PEV     E  LE P   +      V  P+  AP      PK  +P+   
Sbjct: 10653 AIPPKPESPPPEVFEEPEEVALEEPPAEV------VEEPEPAAPPQVTVPPKKPVPEKKA 10706

Query: 2521  PGFKAEGPEVD-VNLPKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPKI 2579
             P   A+ PE+  V +P+       PK  +    V +  P+ K + P  K+PE+    PK 
Sbjct: 10707 PAVVAKKPELPPVKVPEV------PKEVVPEKKVPLVVPK-KPEAPPAKVPEV----PKE 10755

Query: 2580  SMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKMP 2639
              +P+  + +  PK        +P+V      P+  +   K  +  P+     P    + P
Sbjct: 10756 VVPEKKVAV--PKKPEVPPAKVPEV------PKKPVLEEKPAVPVPERAESPPPEVYEEP 10807

Query: 2640  KVKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKLKGPKFKMPE 2699
             +   P+  +       P+ +  +P A+          E P+V    P    + PK  +PE
Sbjct: 10808 EEIAPEEEI------APEEEKPVPVAEE---------EEPEVP---PPAVPEEPKKIIPE 10849

Query: 2700  MNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHG 2759
                K P I  P+       P  K       P+ E  ++ P++  + P      P  DV  
Sbjct: 10850 K--KVPVIKKPE------APPPKE------PEPEKVIEKPKLKPRPPPPPPAPPKEDVKE 10895

Query: 2760  PDWHLK-MPKIKMP-------KISMPGFKGEGPDVDVN--LPKADIDVSGPKVDVECPDV 2809
               + LK +PK K+P       K+ +   K  G +  V   LP+   +   PK +V    V
Sbjct: 10896 KIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPE---PKEEVVLKSV 10952

Query: 2810  NIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDVDV-TGPKVEGDLKGPE 2868
               + PE +   PK + P+   K  K ++P+       PK   +V+V T  K E  +  P 
Sbjct: 10953 LRKRPEEE--EPKVE-PKKLEKVKKPAVPEPP----PPKPVEEVEVPTVTKRERKIPEPT 11005

Query: 2869  VDLKGPKVDIDVPDVNVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDVSGP 2928
                K P++    P + +  P+   K P+ ++     P  +   PE         V V G 
Sbjct: 11006 ---KVPEIK---PAIPLPAPEPKPK-PEAEVKTIKPPPVE---PEPTPIAAPVTVPVVGK 11055

Query: 2929  KVDVEGPDVNIEGPEGKLKGPKFKMP 2954
             K + + P      P+G +KG   K P
Sbjct: 11056 KAEAKAPKEEAAKPKGPIKGVPKKTP 11081



 Score = 83.2 bits (204), Expect = 7e-15
 Identities = 333/1467 (22%), Positives = 563/1467 (38%), Gaps = 255/1467 (17%)

Query: 747   LKMPKMKMPKFSVPGFKAEGPEVDVNLPKADVDISGPKIDVTAPDVSIE-EPEGKLKGPK 805
             LK P  K+P+     F+ +   + +++ K +      K  VT P   +  +P+  +   K
Sbjct: 9832  LKPPPPKVPEEPKKVFEEK---IRISITKRE------KEQVTEPAAKVPMKPKRVVAEEK 9882

Query: 806   FKMPEMNIKVPKISMPDVDLHLKGPNVKGEYDVTMPK----VESEIKVPDVELKSAKMDI 861
               +P   +  P + +P+V   L+   V  E +V        VE E +    E +    + 
Sbjct: 9883  VPVPRKEV-APPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEE 9941

Query: 862   DVPDVEVQGPDWHLK-MPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVGVEVPDV 920
              VP + V+ P+   K +P+ K P   +P  K   P     +PK   +    KV V +P  
Sbjct: 9942  VVPVIPVKVPEVPRKPVPEEKKP-VPVPKKKEAPPAKVPEVPKKPEE----KVPVLIPK- 9995

Query: 921   NIEGPEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGPKVKGEYDMTVPKL-EGDLKGPK 979
                    K K P  K+PE+    PK  +P+  + +  PK        VP++ +  +   K
Sbjct: 9996  -------KEKPPPAKVPEV----PKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKK 10044

Query: 980   VDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGPEFDVNLSKANVDISAPKVDTNAP 1039
             V V AP  +++ P    K+P++  PK  +P  K   P               PK      
Sbjct: 10045 VPVPAPK-KVEAPP--AKVPEV--PKKLIPEEKKPTP--------------VPK------ 10079

Query: 1040  DLSLEGPEGKLKGPKFKMPEMHFRAP-KMSLPDVDLDLKGPKMKGNVDISAPKIEGEMQV 1098
                      K++ P  K+P+     P  ++LP  +  L   ++    ++     E E  +
Sbjct: 10080 ---------KVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLP---EEEEVL 10127

Query: 1099  PDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLKGEGPEVDVNLPKADVVVS 1158
             P+ +   P+ +   P+ E        +IP  +     +P  +   PE +  +P+ +V+  
Sbjct: 10128 PEEEEVLPEEEEVLPEEE--------EIPPEEE---EVPPEEEYVPEEEEFVPEEEVLPE 10176

Query: 1159  -GPKVDIEAP--DVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVKGDVDV 1215
               PKV + AP  ++  +  E K+  PK K      K P++     +  +  PK +  + V
Sbjct: 10177 VKPKVPVPAPVPEIKKKVTEKKVVIPK-KEEAPPAKVPEVPKKVEEKRIILPKEEEVLPV 10235

Query: 1216  SVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMPKFSMPGFKGEGREVD 1275
              V +   E  + + EI  P+      +VE   P    ++ K  +P+   P  K       
Sbjct: 10236 EVTEEPEEEPISEEEI--PEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPK------K 10287

Query: 1276  VNLPKADIDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLNLKG- 1334
             V  P A +    P+  V VP    E P  K+     K+PE     PK    +     KG 
Sbjct: 10288 VEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPK---KEAVPPAKGR 10344

Query: 1335  PKLKGDVDVSLPEVEGEMKVPDVDIKGPKVDISAPDVDVHGPDWHLKMPKVKMPKFSMPG 1394
               L+  V V+  +     +  ++++   +V+    + + H  + + +             
Sbjct: 10345 TVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFE------------- 10391

Query: 1395  FKGEGPEVD--VKLPKADVDVSG---------PKMDAEVPDVNIEGPDAKLKGPKFKMPE 1443
              +GE  EV+  +KL +  V+               +AE  +V  E P A  KGP  ++ E
Sbjct: 10392 -EGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEV-FEKPKAPPKGP--EISE 10447

Query: 1444  MSIKPQKISIPDVGLHLKGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKVDINAPDVEVHG 1503
               I P+K            P  K      VP+ E   K P+V    PK  +    V V  
Sbjct: 10448 KIIPPKK------------PPTK-----VVPRKEPPAKVPEV----PKKIVVEEKVRV-- 10484

Query: 1504  PDWHLKMPKVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPDVNLE-APEGKL 1562
             P+   ++P  K+P+   P  K   PE  + +P A    + P     VP+   E  PE K+
Sbjct: 10485 PE-EPRVPPTKVPEVLPP--KEVVPEKKVPVPPAKKPEAPPP---KVPEAPKEVVPEKKV 10538

Query: 1563  KGPKFKMPSMNIQTHKISMPDVGLNLKAPKLKTDVDVSLPKVEGDLKGPEIDVKAPKMDV 1622
               P  K P    +     +P+V    KA   +  V  ++P  + +   PE+  +APK  V
Sbjct: 10539 PVPPPKKP----EVPPTKVPEVP---KAAVPEKKVPEAIPP-KPESPPPEVP-EAPKEVV 10589

Query: 1623  NVGDIDIEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDMDVSVPKVE--- 1679
                 +    P+ K +    K+PE    APK  +P+  + +  PK        VP+V    
Sbjct: 10590 PEKKVPAAPPK-KPEVTPVKVPE----APKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVA 10644

Query: 1680  -GEMKVPDVDIKGPKVDIDAPDVEVHDPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPK 1738
               E KVP+     PK +   P+V     +  L+ P  ++ +   P   A  P+V V   K
Sbjct: 10645 VPEKKVPEA--IPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEP---AAPPQVTVPPKK 10699

Query: 1739  ADIDVSGPSVDTDAPDLDIEGPEGKLKGSKFKMPKLNIKAPKVSMPDVDLNLKGPKLKGE 1798
                +   P+V    P+L              K+P++    PK  +P+  + L  PK    
Sbjct: 10700 PVPEKKAPAVVAKKPEL-----------PPVKVPEV----PKEVVPEKKVPLVVPKKPEA 10744

Query: 1799  IDASVPELEGDLRGPQVDVKGPFVEAEVPDVDLECPDAKLKGPKFKMPEMHFKAPKISMP 1858
               A VPE+  ++               VP+  +  P  K + P  K+PE+  K      P
Sbjct: 10745 PPAKVPEVPKEV---------------VPEKKVAVP-KKPEVPPAKVPEVPKKPVLEEKP 10788

Query: 1859  DVDLHLKG----PKVKGDADVSVPKLEGDLTGPSVGVEVPDVELECPD----AKLKGPKF 1910
              V +  +     P+V  + +   P+ E     P     VP  E E P+    A  + PK 
Sbjct: 10789 AVPVPERAESPPPEVYEEPEEIAPEEE---IAPEEEKPVPVAEEEEPEVPPPAVPEEPKK 10845

Query: 1911  KMPDMHFKAPKISMPDVDLHLKGPKVKGDVDVSVPKLEGDLTGPSVGVEVPDVELECPDA 1970
              +P+   K P I  P+        + + +  +  PKL+     P       DV+ +    
Sbjct: 10846 IIPEK--KVPVIKKPEAP---PPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQL 10900

Query: 1971  KLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKM 2030
             K   PK K+PE      K+ +  + +     KV+  +    P+ + E+ +  V  K P  
Sbjct: 10901 KAI-PKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRP-- 10957

Query: 2031  DIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKAEGPEVDV-NLPKADVVVSGP-KVDVEV 2088
             + + P V+        K+ K+K P    P       EV+V  + K +  +  P KV    
Sbjct: 10958 EEEEPKVEPK------KLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIK 11011

Query: 2089  PDVSLEGPEGKLKGPKLKMPEMHFKAPKISMPDVDLHLKGPKVKGDVDVSLPKLEGDLTG 2148
             P + L  PE K K      PE   K            +K P V+ +       +   + G
Sbjct: 11012 PAIPLPAPEPKPK------PEAEVKT-----------IKPPPVEPEPTPIAAPVTVPVVG 11054

Query: 2149  PSVDVEVPDVELECPDAKLKGPKFKMP 2175
                + + P  E   P   +KG   K P
Sbjct: 11055 KKAEAKAPKEEAAKPKGPIKGVPKKTP 11081



 Score = 78.6 bits (192), Expect = 2e-13
 Identities = 233/1006 (23%), Positives = 398/1006 (39%), Gaps = 164/1006 (16%)

Query: 3539  KAPKISMPDIDLNLKGPKVKGDVDISLPKLEGDLKGPEVDIKGPKVDINAPDVDVHGPDW 3598
             +AP   +P++      PK   +  I LPK E ++   EV  +  +  I+  ++    P  
Sbjct: 10206 EAPPAKVPEV------PKKVEEKRIILPK-EEEVLPVEVTEEPEEEPISEEEIPEEPPSI 10258

Query: 3599  HLKMPKVKMPKFSMPGFKGEGPEVDVTLPKADIDISGPNVDVDVPDVNIEGPDAKLKGPK 3658
               ++ +V  P+      K   PE    +PK  ++     V   +P+  +  P  K + P 
Sbjct: 10259 E-EVEEVAPPRVPEV-IKKAVPEAPTPVPKK-VEAPPAKVSKKIPEEKVPVPVQKKEAPP 10315

Query: 3659  FKMPEMNIKAP--KISMPDFDLNLKGPKMKGDVVVSLPKVEGDLKGPEVDIKGPKVDIDT 3716
              K+PE+  K P  K+ +P  +     P  KG  V+   KV    +  EV +K  +++++ 
Sbjct: 10316 AKVPEVPKKVPEKKVLVPKKE---AVPPAKGRTVLE-EKVSVAFR-QEVVVK-ERLELEV 10369

Query: 3717  PDINIE--GSEGKFKGPK--FKIPEMH--LKAPKISMPDIDLNLKGPKVKGDVDVSLPKM 3770
              +  +E    E +F   +  F+  E H   +  K+    ++   +  KV   ++V   + 
Sbjct: 10370 VEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEE 10429

Query: 3771  EGDLKGPEVDIKGPKVD------INAPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDV 3824
                 + P+   KGP++          P   V   +   K+P+V  PK  +   K   P+ 
Sbjct: 10430 VEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEV--PKKIVVEEKVRVPEE 10487

Query: 3825  DVNLPKADLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKG 3884
                 P    +V  PK  +    V +  P  K + P  K+PE    APK  +P+  + +  
Sbjct: 10488 PRVPPTKVPEVLPPKEVVPEKKVPVP-PAKKPEAPPPKVPE----APKEVVPEKKVPVPP 10542

Query: 3885  PKVKGDMDVSLPKVEGDMQVPDLDIKGPKVDINAPDVDVRGPDWHLKMPKIKMPKISMPG 3944
             PK        +P      +VP   +   KV    P      P    + PK  +P+  +P 
Sbjct: 10543 PKKPEVPPTKVP------EVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPA 10596

Query: 3945  FKGEGPEV-DVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISM 4003
                + PEV  V +P+A  +V  P+  V VP      P  K + P  K+PE+    PK+++
Sbjct: 10597 APPKKPEVTPVKVPEAPKEVV-PEKKVPVP------PPKKPEVPPTKVPEV----PKVAV 10645

Query: 4004  PDFDLHLKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKV 4063
             P+          K   +   PK E     PEV  +  +V ++ P  +V           V
Sbjct: 10646 PE----------KKVPEAIPPKPES--PPPEVFEEPEEVALEEPPAEV-----------V 10682

Query: 4064  KMPKFSMPGFKGEGPEVDVNLPKADIDVSGPKVDIDTPDIDIHGPEGKLKGPKFKMPDLH 4123
             + P+ + P      P+V V   K   +   P V    P++           P  K+P++ 
Sbjct: 10683 EEPEPAAP------PQVTVPPKKPVPEKKAPAVVAKKPEL-----------PPVKVPEV- 10724

Query: 4124  LKAPKISMPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPD 4183
                PK  +PE  + L  PK        +P+V  ++  PE  +  PK   +VP   V  P+
Sbjct: 10725 ---PKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVV-PEKKVAVPKKP-EVPPAKV--PE 10777

Query: 4184  WHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADL---DVSGPKVDIDVPDVNIEGPD--- 4237
                K    + P   +P  + E P  +V     ++   +   P+ +  VP    E P+   
Sbjct: 10778 VPKKPVLEEKPAVPVPE-RAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPP 10836

Query: 4238  -AKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGP 4296
              A  + PK  +PE   K P I  P+       P  K       P+ E  ++ P++  + P
Sbjct: 10837 PAVPEEPKKIIPEK--KVPVIKKPE------APPPKE------PEPEKVIEKPKLKPRPP 10882

Query: 4297  KVDIDAPDVDVHGPDWHLK-MPKVKMP-------KFSMPGFKGEGPDVDV--TLPKADIE 4346
                   P  DV    + LK +PK K+P       K  +   K  G +  V   LP+   E
Sbjct: 10883 PPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPE 10942

Query: 4347  ISGPKVDIDAPDVSIEGPDAKLKGPKFKMPEM-NIKAPKISMPDIDFNLKGPKVKGDVDV 4405
                PK ++    V  + P+   + PK +  ++  +K P +  P        P  K   +V
Sbjct: 10943 ---PKEEVVLKSVLRKRPEE--EEPKVEPKKLEKVKKPAVPEP--------PPPKPVEEV 10989

Query: 4406  SLPKV-EGDLKGPEIDIKGPSLDIDTPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDF 4464
              +P V + + K PE   K P +    P + +  PE K   PK +     IK P +     
Sbjct: 10990 EVPTVTKRERKIPE-PTKVPEI---KPAIPLPAPEPK---PKPEAEVKTIKPPPVEP--- 11039

Query: 4465  DLHLKGPKVKGDVDVSLPKVESDLKGPEVDIEGPEGKLKGPKFKMP 4510
                 +   +   V V +   +++ K P+ +   P+G +KG   K P
Sbjct: 11040 ----EPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTP 11081



 Score = 70.1 bits (170), Expect = 6e-11
 Identities = 274/1312 (20%), Positives = 495/1312 (37%), Gaps = 212/1312 (16%)

Query: 2825  MPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPEVDLKGP-KVDIDVPDV 2883
             +P +  K P++    +      P+ K  V V   K     K PEV  K   KV + +P  
Sbjct: 9943  VPVIPVKVPEVPRKPV------PEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKK 9996

Query: 2884  NVQGPDWHLKMPKMKMPKFSMP---GFKAEGPEVDV-NLPKADVDVSGPKVDVEGPDVNI 2939
                 P    ++PK  +P+  +P     K E P   V  +PK  V     KV V  P   +
Sbjct: 9997  EKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEK--KVPVPAPK-KV 10053

Query: 2940  EGPEGKL-KGPKFKMPEMNIKAP---KIPMPDFDLHLKGPKVKGDVDISLPKVEGDLKG- 2994
             E P  K+ + PK  +PE     P   K+  P   +  K   V   V ++LP+ E  L   
Sbjct: 10054 EAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVP--VPVALPQEEEVLFEE 10111

Query: 2995  ---PEVDIRGPQVDIDVPDVGVQGPDWHLKMPK---VKMPKFSMPGFKGEGPDVDVNLPK 3048
                PE ++  P+ +  +P+     P+    +P+   +   +  +P  +   P+ +  +P+
Sbjct: 10112 EIVPEEEVL-PEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPE 10170

Query: 3049  AD-LDVSGPKVDID--VPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKV 3105
              + L    PKV +   VP++  +  E K+  PK +      +AP   +P++      PK 
Sbjct: 10171 EEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKE------EAPPAKVPEV------PKK 10218

Query: 3106  KGDMDVSLPKVEGDMKVPDVDIKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISMPGFKG 3165
               +  + LPK E  + V +V  +  +  I+  ++  + P    ++ ++  P++     K 
Sbjct: 10219 VEEKRIILPKEEEVLPV-EVTEEPEEEPISEEEIPEEPPSIE-EVEEVAPPRVPEV-IKK 10275

Query: 3166  EGPEVDVNLPK------ADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKI 3219
               PE    +PK      A +    P+  V VP    E P AK+     K+PE  +  PK 
Sbjct: 10276 AVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKK 10335

Query: 3220  SMPDLDLNLKGPKMKG----EVDVSLANVEGDLKGPALDIKGPKIDVD--APDIDIHGPD 3273
                        P  KG    E  VS+A  +  +    L+++  + +V+    + + H  +
Sbjct: 10336 EAV--------PPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVE 10387

Query: 3274  AKLKGPKLKMPDMHVNMPKISMPEIDLNLKGSKLKGDVDVSGPKLEGDIKAPSLDIKGPE 3333
                +  +    +  +   K+    ++   +  K+   ++V   +     + P    KGPE
Sbjct: 10388 EYFEEGEFHEVEEFI---KLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPE 10444

Query: 3334  VD--VSGPKLNIEGKSKKSRFKLPKFNFSGSKVQTPEVDVKGKKPDIDITGPKVDINAPD 3391
             +   +  PK            K P      +KV  P  +   K P++    PK  +    
Sbjct: 10445 ISEKIIPPK------------KPP------TKV-VPRKEPPAKVPEV----PKKIVVEEK 10481

Query: 3392  VEVQGKVKGSKFKMPFLSISSPKVSMPDVELNLKSPKVKGDLDIAGPNLEGDFKGPKVDI 3451
             V V  + +    K+P   +  PK  +P+ ++ +             P  + +   PKV  
Sbjct: 10482 VRVPEEPRVPPTKVP--EVLPPKEVVPEKKVPVP------------PAKKPEAPPPKVPE 10527

Query: 3452  KAPEVNLNAPDVDVHGPDWNLKMPKMKMPKFSVSGLKAEGPDVAVDLPKGDINIEGPSMN 3511
                EV           P+  + +P  K P+          P    ++PK  +        
Sbjct: 10528 APKEV----------VPEKKVPVPPPKKPEVP--------PTKVPEVPKAAV-------- 10561

Query: 3512  IEGPDLNVEGPEGGLKGPKFKMPDMNIKAPKISMPDIDLNLKGPKVKGDVDISLPKLEGD 3571
                P+  V  PE     P+   P++  +APK  +P+  +    PK      + +P     
Sbjct: 10562 ---PEKKV--PEAIPPKPESPPPEVP-EAPKEVVPEKKVPAAPPKKPEVTPVKVP----- 10610

Query: 3572  LKGPEVDIKGPKVDINAPDVDVHGPDWHLKMPKVKMPKFSMPGF---KGEGPEVDVTLPK 3628
              + P+  +   KV +  P      P    ++PKV +P+  +P     K E P  +V    
Sbjct: 10611 -EAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEP 10669

Query: 3629  ADIDISGPNVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKA--------PKISMPDFDLNL 3680
              ++ +  P  +V V +     P      PK  +PE    A        P + +P+    +
Sbjct: 10670 EEVALEEPPAEV-VEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEV 10728

Query: 3681  KGPKMKGDVVVSLPKVEGDLKGPEVDIKGPKVDIDTPDINIEGSEGKFKGPKFKIPEMHL 3740
               P+ K  +VV         K PEV    PK  +    + +     K + P  K+PE+  
Sbjct: 10729 V-PEKKVPLVVPKKPEAPPAKVPEV----PKEVVPEKKVAV---PKKPEVPPAKVPEVPK 10780

Query: 3741  K-----APKISMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPEVDIKGPKVDINAPDVDV 3795
             K      P + +P+       P+V  + +   P+ E     PE +   P  +   P+V  
Sbjct: 10781 KPVLEEKPAVPVPE-RAESPPPEVYEEPEEIAPEEE---IAPEEEKPVPVAEEEEPEVP- 10835

Query: 3796  QGPDWHLKMPKVKMPKFSMPGFK------GEGPDVDVNLPKADLDVSGPKVDIDVPDVNI 3849
               P    + PK  +P+  +P  K       + P+ +  + K  L    P      P  ++
Sbjct: 10836 --PPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDV 10893

Query: 3850  EGPEGKLKG-PKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMQVPDLD 3908
             +    +LK  PK K+PE      K+ +  + +     KV+  +    P+ + ++ +  + 
Sbjct: 10894 KEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVL 10953

Query: 3909  IKGPKVDINAPDVDVRGPDWHLKMPKIKMPKISMPGFKGEGPEVDV-NLPKADLDVSGP- 3966
              K P+ +   P V+ +      K+ K+K P +  P       EV+V  + K +  +  P 
Sbjct: 10954 RKRPEEE--EPKVEPK------KLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPT 11005

Query: 3967  KVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKM 4026
             KV    P + +  P+ K K      PE  +K            +K P V+ +       +
Sbjct: 11006 KVPEIKPAIPLPAPEPKPK------PEAEVKT-----------IKPPPVEPEPTPIAAPV 11048

Query: 4027  EGDLKAPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGP 4078
                +   + + K PK +   P   + G       P     +   PG  GE P
Sbjct: 11049 TVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKP 11100



 Score = 60.8 bits (146), Expect = 4e-08
 Identities = 274/1258 (21%), Positives = 479/1258 (38%), Gaps = 197/1258 (15%)

Query: 3405  MPFLSISSPKVSMPDVELNLKSPKVKGDLDIAGPNLEGDFKGPKVDIKAPE-VNLNAPDV 3463
             +P + +  P+V    V      P+ K  + +         K P+V  K  E V +  P  
Sbjct: 9943  VPVIPVKVPEVPRKPV------PEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKK 9996

Query: 3464  DVHGPDWNLKMPKMKMPKFSVS---GLKAEGPDVAV-DLPKGDINIEGPSMNIEGP-DLN 3518
             +   P    ++PK  +P+  V      K E P   V ++PK  +    P   +  P    
Sbjct: 9997  EKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPV----PEKKVPVPAPKK 10052

Query: 3519  VEGPEGGL-KGPKFKMPDMNIKAP---KISMPDIDLNLKGPKVKGDVDISLPKLEGDLKG 3574
             VE P   + + PK  +P+     P   K+  P   +  K   V   V ++LP+ E  L  
Sbjct: 10053 VEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVP--VPVALPQEEEVLFE 10110

Query: 3575  ----PEVDIKGPKVDINAPDVDVHGPDWHLKMPKVKMP--KFSMPGFKGEGPEVDVTLPK 3628
                 PE ++   + ++   + +V   +  +   + ++P  +  +P  +   PE +  +P+
Sbjct: 10111 EEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPE 10170

Query: 3629  ADI--DISGPNVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLNLKGPKMK 3686
              ++  ++  P V V  P   I+    K+   K  +P+   +AP   +P+       PK  
Sbjct: 10171 EEVLPEVK-PKVPVPAPVPEIK---KKVTEKKVVIPKKE-EAPPAKVPEV------PKKV 10219

Query: 3687  GDVVVSLPKVEGDL------KGPEVDIKGPKVDIDTPDINIEGSEGKFKGP---KFKIPE 3737
              +  + LPK E  L      +  E  I   ++  + P I         + P   K  +PE
Sbjct: 10220 EEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPE 10279

Query: 3738  MHLKAPK-ISMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPEVDIKGPKVDINAPDVDVQ 3796
                  PK +  P   ++ K P+ K  V V   K     K PEV  K P+  +  P  +  
Sbjct: 10280 APTPVPKKVEAPPAKVSKKIPEEKVPVPVQ-KKEAPPAKVPEVPKKVPEKKVLVPKKEAV 10338

Query: 3797  GPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPEGKL 3856
              P    K   V   K S+  F+ E     V   + +L+V   +V+    +      E   
Sbjct: 10339 PP---AKGRTVLEEKVSV-AFRQEV----VVKERLELEVVEAEVEEIPEEEEFHEVEEYF 10390

Query: 3857  KGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMQVPDLDIKGPKVDI 3916
             +  +F   E  IK   +    ++   +  KV   ++V   +     + P    KGP  +I
Sbjct: 10391 EEGEFHEVEEFIK---LEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGP--EI 10445

Query: 3917  NAPDVDVRGPDWHL---KMPKIKMPKISMPGFKGEGPEV--DVNLPKADLDVSGPKVDVD 3971
             +   +  + P   +   K P  K+P++       E   V  +  +P   +    P  +V 
Sbjct: 10446 SEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEV- 10504

Query: 3972  VPDVNIEGPDAKL-KGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKMEGDL 4030
             VP+  +  P AK  + P  K+PE    APK  +P+  + +  PK        +P++    
Sbjct: 10505 VPEKKVPVPPAKKPEAPPPKVPE----APKEVVPEKKVPVPPPKKPEVPPTKVPEV---- 10556

Query: 4031  KAPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVD-VNLPKADI 4089
               P+  +   KV    P      P    + PK  +P+  +P    + PEV  V +P+A  
Sbjct: 10557 --PKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPK 10614

Query: 4090  DVSGPKVDIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKMKGDVDV 4149
             +V  P+  +  P      P  K + P  K+P++    PK+++PE  +    P        
Sbjct: 10615 EVV-PEKKVPVP------PPKKPEVPPTKVPEV----PKVAVPEKKVPEAIPPKPES--- 10660

Query: 4150  SLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVD 4209
               P  E   +  EV ++ P  ++ V + +   P      PK  +P+   P    + P++ 
Sbjct: 10661 --PPPEVFEEPEEVALEEPPAEV-VEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELP 10717

Query: 4210  -VNLPKADLDV-SGPKVDIDVPDVNIEGPDAKL-KGPKFKMPEMNIKAPKISMPDFDLHL 4266
              V +P+   +V    KV + VP    E P AK+ + PK  +PE  +  PK          
Sbjct: 10718 PVKVPEVPKEVVPEKKVPLVVPK-KPEAPPAKVPEVPKEVVPEKKVAVPK---------- 10766

Query: 4267  KGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSM 4326
               P+V       +P+V      P+  +   K  +  P+     P    + P+   P+  +
Sbjct: 10767 -KPEVP---PAKVPEV------PKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEI 10816

Query: 4327  PGFKGEGPDVDVTLPKADIEISGPKVDIDAPDVSIEGPDAKLKGPKFKMPEMNIKAPKIS 4386
                    P+ +  +P A+ E          P+V    P A  + PK  +PE   K P I 
Sbjct: 10817 ------APEEEKPVPVAEEE---------EPEVP---PPAVPEEPKKIIPEK--KVPVIK 10856

Query: 4387  MPDIDFNLKGPKVKGDVDVSLPKVEGDLKGPEIDIKGPSLDIDTPDVNIEGPEGKLKG-P 4445
              P+       P  K       P+ E  ++ P++  + P      P  +++    +LK  P
Sbjct: 10857 KPE------APPPKE------PEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIP 10904

Query: 4446  KFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVESDL-------KGPEVDIEGP 4498
             K K+PE      K+ +    +     KV+  +    P+ + ++       K PE +    
Sbjct: 10905 KKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKV 10964

Query: 4499  EGKLKGPKFKMPDVHFKSPQISMSDIDLNL------------KGPKIKGDMDISVP---- 4542
             E K K  K K P V    P   + ++++              K P+IK  + +  P    
Sbjct: 10965 EPK-KLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKP 11023

Query: 4543  KLEGDLKGPK----------------VDVKGPKVGIDTPDIDIHGPEGKLKGPKFKMP 4584
             K E ++K  K                V V G K     P  +   P+G +KG   K P
Sbjct: 11024 KPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTP 11081



 Score = 42.0 bits (97), Expect = 0.018
 Identities = 212/1006 (21%), Positives = 374/1006 (37%), Gaps = 175/1006 (17%)

Query: 4347  ISGPKVDIDAPDVSIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDFNLKGPKVKGDVDVS 4406
             I+ P+  I    V  E    K K P  K+ +  +   K+ +P I   LK P  K   +  
Sbjct: 9786  ITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVP-IPKKLKPPPPKVPEE-- 9842

Query: 4407  LPKVEGDLKGPEIDIKGPSLDIDTPDVNIE-GPEGKLKGPKFKMPEMNIKAPKISMPDFD 4465
              PK   + K      K     +  P   +   P+  +   K  +P   + AP + +P+  
Sbjct: 9843  -PKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEV-APPVRVPEVP 9900

Query: 4466  LHLKGPKVKGDVDVSLPKVESDLKGPEVDIEGPEGKLKGPKFKMPDVHFKSPQISMSDID 4525
               L+  +V  + +V +  VE  L   E +    E +    +  +P +  K P++    + 
Sbjct: 9901  KELEPEEVAFEEEV-VTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPV- 9958

Query: 4526  LNLKGPKIKGDMDISVPKLEGDLKGPKVDVKGP-KVGIDTPDIDIHGPEGKLKGPKFKMP 4584
                  P+ K  + +   K     K P+V  K   KV +  P         K K P  K+P
Sbjct: 9959  -----PEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPK--------KEKPPPAKVP 10005

Query: 4585  DLHLKAPKISMPEVDLNLKGPKVKGDMDISLPKVEGDLKGPEVDIRDPKVDIDVPDVDVQ 4644
             ++    PK  +PE  + +  PK        +P+V      P+  + + KV +  P   V+
Sbjct: 10006 EV----PKKPVPEEKVPVPVPKKVEAPPAKVPEV------PKKPVPEKKVPVPAPK-KVE 10054

Query: 4645  GPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADIDVSGPKVDVDVPDVNIEGPDAKL 4704
              P    K+P+V  PK  +P  K   P     +PK  ++   PKV      V +       
Sbjct: 10055 APP--AKVPEV--PKKLIPEEKKPTP-----VPKK-VEAPPPKVPKKREPVPV------- 10097

Query: 4705  KGPKFKMPEMSIKAPKISMPDIDLNLKGPKVKGDVDVTLPKVEGDLKGPEADIKGPKVDI 4764
               P     E  +   +  +P+ ++  +  +V  + +  LP+ E  L  PE +   P+ + 
Sbjct: 10098 --PVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVL--PEEEEIPPEEE- 10152

Query: 4765  NTPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVSLPKADIDVSGPKVDVDIPDVN 4824
               P  + + P+    +P+ ++    +P  K   P V V  P  +I     +  V IP   
Sbjct: 10153 EVPPEEEYVPEEEEFVPEEEV----LPEVK---PKVPVPAPVPEIKKKVTEKKVVIPKKE 10205

Query: 4825  IEGPDAKLKGPKFKMPEINIKAPKIS---------------IPDVDLDLKGPKVKGDFDV 4869
              E P AK+     K+ E  I  PK                 I + ++  + P ++   +V
Sbjct: 10206 -EAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEV 10264

Query: 4870  SVPKVEGTLKG------------------------PEVDLKGPRLDFEGPDAKLSGPSLK 4905
             + P+V   +K                         PE  +  P    E P AK+     K
Sbjct: 10265 APPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKK 10324

Query: 4906  MPSLEISAPK-----------VTAPDVDLHLKAPKIGFSGPKLEGGEVDLKGPKVEAPSL 4954
             +P  ++  PK           V    V +  +   +     +LE  E +++    E P  
Sbjct: 10325 VPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVE----EIPEE 10380

Query: 4955  DVHMDSPDINIEGPDVKIPKFKKPKFGFGAKSPKADIKSPSLDVTVPEAELNLETPEISV 5014
             +   +  +   EG   ++ +F K +     +  + +     ++V         E  E+ V
Sbjct: 10381 EEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEV--------FEAEEVEV 10432

Query: 5015  GGKGKKSKFKMPKIHMSGPKIKAK----KQGFDLNVPGGEIDASLKAPDVDVNIAGPD-A 5069
                     F+ PK    GP+I  K    K+     VP  E  A  K P+V   I   +  
Sbjct: 10433 --------FEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPA--KVPEVPKKIVVEEKV 10482

Query: 5070  ALKVDVKSPKTK--KTMFGKMYFPDVEFDIKSPKFKAEAPLPSPKLEGELQAPDLELSLP 5127
              +  + + P TK  + +  K   P+ +  +  P  K EAP P      +   P+ ++ +P
Sbjct: 10483 RVPEEPRVPPTKVPEVLPPKEVVPEKKVPV-PPAKKPEAPPPKVPEAPKEVVPEKKVPVP 10541

Query: 5128  AIHVEGLDIKAKAPKVKMPDVDISVPKIEGDLKGPKVQANLGAPDINI-EGLDAKVKTPS 5186
                      K + P  K+P+V             PK       P+  + E +  K ++P 
Sbjct: 10542 P------PKKPEVPPTKVPEV-------------PKA----AVPEKKVPEAIPPKPESPP 10578

Query: 5187  FGI-SAPQVSIPDVNVNLKGPKIKGDVPSVGLEGPDVDLQGPEAKIKFP---KFSMPKIG 5242
               +  AP+  +P+  V    PK     P    E P   +  PE K+  P   K  +P   
Sbjct: 10579 PEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVV--PEKKVPVPPPKKPEVPPTK 10636

Query: 5243  IPGV-KMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDL 5287
             +P V K+     +V   +P  + +   P+V  E  +V+L+ P  ++
Sbjct: 10637 VPEVPKVAVPEKKVPEAIPP-KPESPPPEVFEEPEEVALEEPPAEV 10681


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score = 79.3 bits (194), Expect = 1e-13
 Identities = 179/638 (28%), Positives = 231/638 (36%), Gaps = 104/638 (16%)

Query: 5160 KGPKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPSVGLEG 5219
            KG K QA    P   + G+      P F  S  +    D+   L  P +KGD   +G  G
Sbjct: 514  KGEKGQAGATGPK-GLPGIPGAPGAPGFPGSKGEPG--DI---LTFPGMKGDKGELGSPG 567

Query: 5220 PD--VDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQ--------LPSLEGDLRGP 5269
                  L G   +   P       G+PG K E GG     +        LP L G++   
Sbjct: 568  APGLPGLPGTPGQDGLP-------GLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPM 620

Query: 5270 DVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGL 5329
                 GP   +   G+   + N   P + GP  D    G ++       +P        +
Sbjct: 621  GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGD---PGQTITQPGKPGLPGNPGRDGDV 677

Query: 5330 NLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGA 5389
             L G  G     G    +PGI  + K   G P + L GP   G     G I  P  + G 
Sbjct: 678  GLPGDPGLPGQPG----LPGIPGS-KGEPGIPGIGLPGPP--GPKGFPG-IPGPPGAPGT 729

Query: 5390 PD-LSLEASEGSIKLPKMK-LPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRI 5447
            P  + LE   G    P  K  P F +  P     +    P   G L GP  D    GP  
Sbjct: 730  PGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGL----PGFKGAL-GPKGDRGFPGP-- 782

Query: 5448 SAPNVDFNLEG-PKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMP---------GI 5497
              P     L+G P  KG +G  G+  GP    GLPGIGVQG  G   +P         GI
Sbjct: 783  PGPPGRTGLDGLPGPKGDVGPNGQ-PGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGI 841

Query: 5498 KSSGCDVNLPGVNVKLPTGQISGPEIKG-----------GL--KGSEVGFHGAAPDISVK 5544
                 D   PG++V  P G+   P I G           GL  K    GF G   ++ + 
Sbjct: 842  PGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMM 901

Query: 5545 GPAFNMASPESDFGINLKG--PKIKGGADVSGGVSAPDISLGEGHLSVKGSGGE-----W 5597
            GP      P    GI  +   P +KG   + G    P      G    KGS GE      
Sbjct: 902  GP----PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLP------GPTGEKGSKGEPGLPGP 951

Query: 5598 KGPQVSSALNLDTSKFAGGL----HFSGPKVEGGVKG--GQIGLQA-PGL-SVSGPQGH- 5648
             GP   + L     K   GL      SGPK   G+ G  GQ GL   PGL    GP+G+ 
Sbjct: 952  PGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNP 1011

Query: 5649 -LESGSGKVTFPKMK--IPKFTFSGRELVGREMGVDVHFPKAEASIQAGAGDGEWEESEV 5705
             L    G +  P +K  I    F G + V    G     P    S       G+  +  +
Sbjct: 1012 GLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPS-GVPGQPGSPGLPGQKGDKGDPGI 1070

Query: 5706 KLKKSKIKMPKFNFSKPKGKGGVTGSP-EASISGSKGD 5742
                S I +P      PKG+ G+ G P    I GS GD
Sbjct: 1071 ----SSIGLP--GLPGPKGEPGLPGYPGNPGIKGSVGD 1102



 Score = 65.5 bits (158), Expect = 2e-09
 Identities = 229/925 (24%), Positives = 316/925 (34%), Gaps = 193/925 (20%)

Query: 4663 PGFKGE-GPDVDVNLPKAD--------IDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPE 4713
            PG  G  G D DV LP             + G K +  +P + + GP     GPK     
Sbjct: 665  PGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPP----GPK----- 715

Query: 4714 MSIKAPKISMPDIDLNLKGPKVKGDVDVTLPKVEGDLKGPEADIKGPKVDINTPDVDVHG 4773
                      P I      P   G + +  P       GP+ +          P   + G
Sbjct: 716  --------GFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGE----------PGFALPG 757

Query: 4774 PDWHLKMPKVKMPKFSMPGFKGE-GPDVDVSLP-------KADID-VSGPKVDVDIPDVN 4824
            P               +PGFKG  GP  D   P       +  +D + GPK DV      
Sbjct: 758  PPGPP----------GLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV------ 801

Query: 4825 IEGPDAKLKGPKFK--MPEINIKAPKISIPDVDLDLKGPKVKGDFDVSVPKVEGTLKGPE 4882
              GP+ +  GP     +P I ++ P             P + G   +  P + G + G +
Sbjct: 802  --GPNGQ-PGPMGPPGLPGIGVQGPP----------GPPGIPGP--IGQPGLHG-IPGEK 845

Query: 4883 VDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLHLKAPKIGFSGPKLEGGEV 4942
             D   P LD  GP  +   P +      I  P        L  KA   GF G K   GE+
Sbjct: 846  GDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG----LPGKAGASGFPGTK---GEM 898

Query: 4943 DLKGPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKFGFGAKSPKADIKSPSLDVTVPE 5002
             + GP      L +   S    ++G D    +   P    G    K     P L      
Sbjct: 899  GMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLP----GPTGEKGSKGEPGLPGPPGP 954

Query: 5003 AELNLETPEISVGGKGKKSKFKMPKIH-MSGPKIKAKKQGFDLNVPGGEIDASLKAPDVD 5061
             + NL      +G KG+K +  +P I  +SGPK      G D   PG      L  P   
Sbjct: 955  MDPNL------LGSKGEKGEPGLPGIPGVSGPKGYQGLPG-DPGQPGLSGQPGLPGPPGP 1007

Query: 5062 VNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEFDIKSPKFKAEAPLP--SPKLEGELQA 5119
                 P    +  +  P   K   G M FP  +  ++ P   +  P    SP L G+   
Sbjct: 1008 KG--NPGLPGQPGLIGPPGLKGTIGDMGFPGPQ-GVEGPPGPSGVPGQPGSPGLPGQKG- 1063

Query: 5120 PDLELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGDLKGPKVQANLGAPDI----NI 5175
               +   P I   GL      P +  P  +  +P   G+   P ++ ++G P +      
Sbjct: 1064 ---DKGDPGISSIGL------PGLPGPKGEPGLPGYPGN---PGIKGSVGDPGLPGLPGT 1111

Query: 5176 EGLDAKVKTPSF----GISAPQ-VSIPDVNVNLKG----------------PKIKGDVPS 5214
             G   +   P F    G   P+ +S P  N  L G                P  KG    
Sbjct: 1112 PGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQ 1171

Query: 5215 VGLEGPDVDLQGPEAKIKFPKFSMP-KIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKL 5273
             G+ GP     G + +   P F  P   G+PG+  + G       LP + G+   P  K 
Sbjct: 1172 DGIPGP----AGQKGEPGQPGFGNPGPPGLPGLSGQKGDGG----LPGIPGNPGLPGPKG 1223

Query: 5274 EGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPG----L 5329
            E        PG          P V GP       GP+L+G      P      PG     
Sbjct: 1224 E--------PGFH------GFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQ 1269

Query: 5330 NLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRG-PSLQGDLA---VSGDIKCPKV 5385
             L G  G   + G+G    GI    K N G P   L G P L+GD     + G+   P +
Sbjct: 1270 GLPGPEGPPGLPGNG----GIKGE-KGNPGQPG--LPGLPGLKGDQGPPGLQGNPGRPGL 1322

Query: 5386 SVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGP 5445
            +    D  L    G    P MK P      PGS       GP+    L GP     L GP
Sbjct: 1323 NGMKGDPGLPGVPG---FPGMKGPS---GVPGS------AGPEGEPGLIGPPGPPGLPGP 1370

Query: 5446 RISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPG-IGVQGLEGNLQMPGIKSSGCDV 5504
               +  +  +   P + G  G  G + GP    GLPG  G  G  G   +PG   +G   
Sbjct: 1371 SGQSIIIKGDAGPPGIPGQPGLKG-LPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRK 1429

Query: 5505 NLPGVNVKLPTGQISGPEIKGGLKG 5529
              PG+  +  T  + GP    GL+G
Sbjct: 1430 GDPGLPGQPGTRGLDGPPGPDGLQG 1454



 Score = 65.1 bits (157), Expect = 2e-09
 Identities = 139/512 (27%), Positives = 179/512 (34%), Gaps = 110/512 (21%)

Query: 5200 NVNLKG-PKIKGDVPSVGLEGPD-------VDLQGPEAKIKFPKFSMPK--IGIPGVKME 5249
            N+ L G P  KG+    G++GP          + GP     FP     K   G PG+ + 
Sbjct: 360  NIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIP 419

Query: 5250 GGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKG- 5308
            G         P L+G    P   L GP     GP +  PS  +  P   GP      KG 
Sbjct: 420  GP--------PGLDGQPGAPG--LPGPP-GPAGPHIP-PSDEICEPGPPGPPGSPGDKGL 467

Query: 5309 ---PSLKGD----------LDASVPSMKVHAPGL-------NLSGVGG-KMQVGGDGVK- 5346
                 +KGD             S P  +   PGL          G  G K Q G  G K 
Sbjct: 468  QGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKG 527

Query: 5347 VPGIDATTKL-----NVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDL-SLEASEGS 5400
            +PGI           + G P   L  P ++GD    G++  P    GAP L  L  + G 
Sbjct: 528  LPGIPGAPGAPGFPGSKGEPGDILTFPGMKGD---KGELGSP----GAPGLPGLPGTPGQ 580

Query: 5401 IKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAP---------- 5450
              LP +  P+     PG       +GP  +  L G   ++   GP    P          
Sbjct: 581  DGLPGLPGPK---GEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQ 637

Query: 5451 NVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGI----------GVQGLEGNLQMPGIKSS 5500
             V  N   P + G  G  G+        GLPG           G  GL G   +PGI  S
Sbjct: 638  GVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGS 697

Query: 5501 GCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGIN 5560
              +  +PG+ +  P G    P I G       G  G    I ++GP      P       
Sbjct: 698  KGEPGIPGIGLPGPPGPKGFPGIPG-----PPGAPGTPGRIGLEGPPGPPGFP------- 745

Query: 5561 LKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFS 5620
              GPK + G  + G    P +   +G L  KG  G    P       LD      GL   
Sbjct: 746  --GPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLD------GL--P 795

Query: 5621 GPKVEGGVKG-----GQIGLQAPGLSVSGPQG 5647
            GPK + G  G     G  GL  PG+ V GP G
Sbjct: 796  GPKGDVGPNGQPGPMGPPGL--PGIGVQGPPG 825



 Score = 59.3 bits (142), Expect = 1e-07
 Identities = 258/1047 (24%), Positives = 346/1047 (33%), Gaps = 196/1047 (18%)

Query: 4664 GFKGEGPDVDVNLPKADIDVSGPKVDVDVPDVNIEGPDAKL--KGPKFKMPEMSIKAPKI 4721
            G KG+  D   N       +SGP     +P   + GP   L   G K +  +     PK 
Sbjct: 472  GVKGDKGDTCFNC--IGTGISGPPGQPGLP--GLPGPPGSLGFPGQKGEKGQAGATGPK- 526

Query: 4722 SMPDIDLNLKGPKVKGDVDVTLPKVEGDLKGPEADI------KGPKVDINTPDVD----V 4771
             +P I      P   G             KG   DI      KG K ++ +P       +
Sbjct: 527  GLPGIPGAPGAPGFPGS------------KGEPGDILTFPGMKGDKGELGSPGAPGLPGL 574

Query: 4772 HGPDWHLKMPKVKMPKFSMPG--FKGE-GPDVDVSLPKADIDVS----------GPKVDV 4818
             G      +P +  PK    G  FKGE GP  +  LP    ++           GP  + 
Sbjct: 575  PGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEK 634

Query: 4819 DIPDVNIEGPDAKLKGPKFKMPEINIKAPKISIP-----DVDLDLKG-PKVKGDFDVSVP 4872
             I  V        + GPK    +   +  K  +P     D D+ L G P + G     +P
Sbjct: 635  GIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQ--PGLP 692

Query: 4873 KVEGTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLHLKAPKIGF 4932
             + G+   P +    P +   GP      P +  P      P              +IG 
Sbjct: 693  GIPGSKGEPGI----PGIGLPGPPGPKGFPGIPGPPGAPGTPG-------------RIGL 735

Query: 4933 SGPKLEGGEVDLKGPKVEAPSLDVHMDSPDINIEGPDVK--IPKFKKPKFGFGAKSPKAD 4990
             GP    G     GPK E          P   + GP     +P FK      GA  PK D
Sbjct: 736  EGPP---GPPGFPGPKGE----------PGFALPGPPGPPGLPGFK------GALGPKGD 776

Query: 4991 IKSPSLDVTVPEAELN-LETPEISVGGKGKKSKFKMPKIHMSGPKIKAKKQGFDLNVPGG 5049
               P          L+ L  P+  VG  G+      P +    P I  +       +PG 
Sbjct: 777  RGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGL----PGIGVQGPPGPPGIPGP 832

Query: 5050 EIDASLKAPDVDVNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEFDIKSPKFKAEAPLP 5109
                 L     +    GP     +DV  P  ++   G    P       SP    +A   
Sbjct: 833  IGQPGLHGIPGEKGDPGPPG---LDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS 889

Query: 5110 S-PKLEGEL-----QAPDLELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGDL--KG 5161
              P  +GE+       P   L +P         ++  P +K  D     P + G    KG
Sbjct: 890  GFPGTKGEMGMMGPPGPPGPLGIPG--------RSGVPGLKGDDGLQGQPGLPGPTGEKG 941

Query: 5162 PKVQANLGAP----DINIEGLDAKVKTPSF----GISAP-----------------QVSI 5196
             K +  L  P    D N+ G   +   P      G+S P                 Q  +
Sbjct: 942  SKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGL 1001

Query: 5197 PDV-----NVNLKG-------PKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIP 5244
            P       N  L G       P +KG +  +G  GP   ++GP      P       G+P
Sbjct: 1002 PGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQ-GVEGPPGPSGVPG-QPGSPGLP 1059

Query: 5245 GVKMEGGGAEVHA-QLPSLEGDLRGPDVKLEGPDVSLKGPGVD--LPSVNLSMPKVSGPD 5301
            G K + G   + +  LP L G    P +     +  +KG   D  LP +  +      P 
Sbjct: 1060 GQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPG 1119

Query: 5302 LDLNLKGPSLKGDLDASVPSMKVHAPGLN--LSGVGGKMQVGGDGVK-VPGID-----AT 5353
            L      P   G    S P      PG    + G G   Q G  G K  PG D     A 
Sbjct: 1120 LPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAG 1179

Query: 5354 TKLNVGAPDVTLRGP-SLQGDLAVSGDIKCPKVSVGAPDLSLEASE-GSIKLPKMKLPQF 5411
             K   G P     GP  L G     GD   P +  G P L     E G    P ++ P  
Sbjct: 1180 QKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIP-GNPGLPGPKGEPGFHGFPGVQGPPG 1238

Query: 5412 GISTPGSDLH--VNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPK-VKGSLGAT 5468
               +PG  L       GPQ      GP     L GP           EGP  + G+ G  
Sbjct: 1239 PPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGP-----------EGPPGLPGNGGIK 1287

Query: 5469 GEIKGPTVGG--GLPGI----GVQGLEGNLQMPGIKSSGCDVNLPGV----NVKLPTG-- 5516
            GE   P   G  GLPG+    G  GL+GN   PG+     D  LPGV     +K P+G  
Sbjct: 1288 GEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVP 1347

Query: 5517 QISGPEIKGGLKG--SEVGFHG-AAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVS 5573
              +GPE + GL G     G  G +   I +KG A     P       L GP  +G   + 
Sbjct: 1348 GSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGP--QGPQGLP 1405

Query: 5574 GGVSAPDISLGEGHLSVKGSGGEWKGP 5600
            G    P      G     G+GG    P
Sbjct: 1406 GPTGPPGDPGRNGLPGFDGAGGRKGDP 1432



 Score = 55.5 bits (132), Expect = 2e-06
 Identities = 142/508 (27%), Positives = 191/508 (37%), Gaps = 81/508 (15%)

Query: 209  PSGSGAASPTGSAVDIRAGAISASGPELQGA-GHSKLQVTMPGIKVGGSGVNVNAKGLDL 267
            P G G   P G    I+  A +   P + G  G     +T PG K G  G N    G D+
Sbjct: 622  PPGFGPPGPVGEK-GIQGVAGNPGQPGIPGPKGDPGQTITQPG-KPGLPG-NPGRDG-DV 677

Query: 268  GGRGGVQVPAVDISSSLGGRAVEVQGPSLE-SGDHGKIKFPTMKVPKFGVSTGREGQTPK 326
            G  G   +P       + G   E   P +   G  G   FP +  P      G  G   +
Sbjct: 678  GLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPP-----GAPGTPGR 732

Query: 327  AGLRVSAPEVSVGHKG--GKPGLTIQAPQLEVSVPSANIEGLEGKLKGPQITGPSLEGDL 384
             GL    P    G  G  G+PG  +  P     +P     G +G L      GP  +GD 
Sbjct: 733  IGLE--GPPGPPGFPGPKGEPGFALPGPPGPPGLP-----GFKGAL------GP--KGDR 777

Query: 385  GLKGAK-PQGHIGVDASAPQIGGSI-----TGPSVEVQAPDIDVQGPGSKLNVPKM--KV 436
            G  G   P G  G+D   P   G +      GP      P I VQGP     +P    + 
Sbjct: 778  GFPGPPGPPGRTGLDG-LPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQP 836

Query: 437  PKFSVSGAKGEE--TGIDVTLPTGE---VTVPGVSGDVSLPEIATGGLEGK-----MKGT 486
                + G KG+    G+DV  P GE     +PG  G +  P   + GL GK       GT
Sbjct: 837  GLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPP--GSPGLPGKAGASGFPGT 894

Query: 487  KVKTPEMIIQKPKISMQDVDLSLGSPKLKGDIKVSAPGVQGD--VKGPQVALKGSRVDIE 544
            K +   M    P   +  +    G P LKGD      G+QG   + GP    KGS+ +  
Sbjct: 895  KGEMGMMGPPGPPGPL-GIPGRSGVPGLKGD-----DGLQGQPGLPGP-TGEKGSKGEPG 947

Query: 545  TPNLEGTLTGPRLGS--PSGKTGTCRISMSEVDLNVAAPKVKGGV--DVTLPRVEGKVKV 600
             P   G +    LGS    G+ G   I        V+ PK   G+  D   P + G+  +
Sbjct: 948  LPGPPGPMDPNLLGSKGEKGEPGLPGIP------GVSGPKGYQGLPGDPGQPGLSGQPGL 1001

Query: 601  PEVDVRGPKVDVSAPDVEAHGPEWNLKMPKMK--MPTFSTPGAKG-EGPDVHMTLP--KG 655
            P     GPK +   P     G    +  P +K  +     PG +G EGP     +P   G
Sbjct: 1002 P--GPPGPKGNPGLP-----GQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPG 1054

Query: 656  DISISGPKVNVEAPDVNLEGLGGKLKGP 683
               + G K +   P ++  GL G L GP
Sbjct: 1055 SPGLPGQKGDKGDPGISSIGLPG-LPGP 1081



 Score = 54.3 bits (129), Expect = 4e-06
 Identities = 224/889 (25%), Positives = 316/889 (35%), Gaps = 167/889 (18%)

Query: 2489 IRGPKVDVNAPDVQAPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDI 2548
            ++GP      P ++     + M  +  PK + PG+   GP     LP     I GP +  
Sbjct: 142  LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGN-PGYP--GPPGIQGLP-GPTGIPGP-IGP 196

Query: 2549 EGPDVNIEGPEGK--LKGPKLKMPEMNIKAPKISMPDFDLHLKGP--------KVKGDVD 2598
             GP   + GP G   L GPK  M  +N + PK    +  L  +GP        + K  +D
Sbjct: 197  PGPP-GLMGPPGPPGLPGPKGNMG-LNFQGPKGEKGEQGL--QGPPGPPGQISEQKRPID 252

Query: 2599 VSLPKVEGDLKG---------------PEVDIKGPKVDINAPDV-GVQGPDWHLKMPKVK 2642
            V   K +  L G               P    KG K +   P   G  G D     P + 
Sbjct: 253  VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312

Query: 2643 -MPKFSMPGFKGE-GPDGDVKLPKADIDVSGPK-VDIEGPDVNIE-GPEGKLKGPKFKMP 2698
             +P    PG+ GE G DG+ K  K D    GP  + I  P   I  G +G +  P     
Sbjct: 313  GLP--GDPGYPGEPGRDGE-KGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE 369

Query: 2699 EMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPK-------VEGDLKGPEVDIKGPK-VDI 2750
            +     P I  P     L GP     +    P         +GD   P + I GP  +D 
Sbjct: 370  KGERGFPGIQGPP---GLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG 426

Query: 2751 DAPDVDVHGPDWHLKMPKIKMPKISMPGFKGE-GPDVDVNLPKADIDVSGPKVDV--ECP 2807
                  + GP            +I  PG  G  G   D  L + +  V G K D    C 
Sbjct: 427  QPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGL-QGEQGVKGDKGDTCFNCI 485

Query: 2808 DVNIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPK-IKGDVDVTGPKVEGDLKG 2866
               I GP G+   P    P      P           TGPK + G     G       KG
Sbjct: 486  GTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKG 545

Query: 2867 PEVDL------KGPKVDIDVPDV----NVQGPDWHLKMPKMKMPKFSMPG--FKAE-GPE 2913
               D+      KG K ++  P       + G      +P +  PK    G  FK E GP 
Sbjct: 546  EPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPP 605

Query: 2914 VDVNLPKADVDVSG---PKVDVEGP--DVNIEGPEGK-----LKGPKFKMPEMNIKAPKI 2963
             +  LP    ++     P     GP  +  I+G  G      + GPK   P   I  P  
Sbjct: 606  GNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGD-PGQTITQPGK 664

Query: 2964 P-MP-----DFDLHLKG-PKVKGDVDI-SLPKVEGDLKGPEVDIRGPQVDIDVPDV---- 3011
            P +P     D D+ L G P + G   +  +P  +G+   P + + GP      P +    
Sbjct: 665  PGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPP 724

Query: 3012 ---------GVQGPDWHLKMPKVK-MPKFSMPG---------FKGE-GPDVDVNLP---- 3047
                     G++GP      P  K  P F++PG         FKG  GP  D   P    
Sbjct: 725  GAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPG 784

Query: 3048 ---KADLD-VSGPKVDIDVPDVNIEGPEGKLKGPKFK--MPEMNIKAPKISMPDIDLNLK 3101
               +  LD + GPK D+        GP G+  GP     +P + ++ P    P I   + 
Sbjct: 785  PPGRTGLDGLPGPKGDV--------GPNGQ-PGPMGPPGLPGIGVQGPP-GPPGIPGPIG 834

Query: 3102 GPKVKGDMDVSLPKVEGDMKVPDVDIKGPKVDINAPDV-DVQGPDWHLKMPKI--KMPKI 3158
             P + G     +P  +GD   P +D+ GP  +  +P +    GP      P +  K    
Sbjct: 835  QPGLHG-----IPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS 889

Query: 3159 SMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPK 3218
              PG KGE   +    P   L + G      VP   ++G D  L+G            P 
Sbjct: 890  GFPGTKGEMGMMGPPGPPGPLGIPGRS---GVP--GLKGDDG-LQG-----------QPG 932

Query: 3219 ISMPDLDLNLKG----PKMKGEVDVSLANVEGDLKGPAL----DIKGPK 3259
            +  P  +   KG    P   G +D +L   +G+   P L     + GPK
Sbjct: 933  LPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPK 981



 Score = 51.2 bits (121), Expect = 3e-05
 Identities = 199/836 (23%), Positives = 285/836 (34%), Gaps = 207/836 (24%)

Query: 2520 MPGFKAEGPEVDVNL---PKADVDISGPK--VDIEGPDVNIEGPEGKLKGPKLKMPE--M 2572
            +PG K E   + ++    PK +    GP     + GP   I GP G    P L  P    
Sbjct: 151  IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGP-TGIPGPIGPPGPPGLMGPPGPP 209

Query: 2573 NIKAPKISMPDFDLHLKGPK-VKGDVDVSLPKVE----GDLKGPEVDIKGPKVDINAP-D 2626
             +  PK +M    L+ +GPK  KG+  +  P        + K P +D++  K D   P D
Sbjct: 210  GLPGPKGNM---GLNFQGPKGEKGEQGLQGPPGPPGQISEQKRP-IDVEFQKGDQGLPGD 265

Query: 2627 VGVQGPDWHLKMPKVKMPKFSMPGFKGE----GPDGDVKLPKADIDVSGPKVDIEGPDVN 2682
             G  GP      P ++ P     G KGE    G  G    P  D +   P +     D  
Sbjct: 266  RGPPGP------PGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPG 319

Query: 2683 IEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKV----KGDVDV-SLPKVEGDLK 2737
              G  G+  G K +  +     P    P + +   G  +    KG++ +  LP  +G+  
Sbjct: 320  YPGEPGR-DGEKGQKGDTGPPGP----PGLVIPRPGTGITIGEKGNIGLPGLPGEKGERG 374

Query: 2738 GPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKADIDV 2797
             P   I+GP      P   V GP                PGF GE               
Sbjct: 375  FP--GIQGPPGLPGPPGAAVMGPP-------------GPPGFPGE--------------- 404

Query: 2798 SGPKVDVECPDVNIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTG 2857
             G K D   P ++I GP G    P           P +  P       GP I    ++  
Sbjct: 405  RGQKGDEGPPGISIPGPPGLDGQPG---------APGLPGPP---GPAGPHIPPSDEICE 452

Query: 2858 PKVEGDLKGP-------EVDLKGPKVD--IDVPDVNVQGPDWHLKMPKMKMPKFSM--PG 2906
            P   G    P       E  +KG K D   +     + GP     +P +  P  S+  PG
Sbjct: 453  PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG 512

Query: 2907 FKAEGPEVDVNLPKADVDVSG-------PKVDVEGPDV----NIEGPEGKLKGPKFK-MP 2954
             K E  +     PK    + G       P    E  D+     ++G +G+L  P    +P
Sbjct: 513  QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572

Query: 2955 EMNIKAPKIPMPDFDLHLKGPKVK-GDVDIS-------------LPKVEGDLKGPEVDIR 3000
             +    P  P  D    L GPK + G +                LP   G +  P     
Sbjct: 573  GL----PGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPP 628

Query: 3001 GPQVDIDVPDVGVQGPDWHLKMPKVKMPK------FSMPGFKG----EGPDVDVNLPKAD 3050
            GP     V + G+QG   +   P +  PK       + PG  G     G D DV LP   
Sbjct: 629  GP-----VGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDP 683

Query: 3051 --------LDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKG 3102
                      + G K +  +P + + GP G    P    P      P        + L+G
Sbjct: 684  GLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPG------RIGLEG 737

Query: 3103 PKVKGDMDVSLPKVEGDMKVPDVDIKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISMPG 3162
            P          P   G    P   + GP            GP               +PG
Sbjct: 738  PP-------GPPGFPGPKGEPGFALPGPP-----------GPP-------------GLPG 766

Query: 3163 FKGE-GPEVDVNLP-------KADLD-VSGPKVDVDVPDVNIEGPDAKLKGPKFK--MPE 3211
            FKG  GP+ D   P       +  LD + GPK DV        GP+ +  GP     +P 
Sbjct: 767  FKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV--------GPNGQ-PGPMGPPGLPG 817

Query: 3212 MNIKAPKISMPDLDLNLKGPKMKGEVDVSLANVEGDLKGPALDIKGPKIDVDAPDI 3267
            + ++ P    P +   +  P + G     +   +GD   P LD+ GP  +  +P I
Sbjct: 818  IGVQGPP-GPPGIPGPIGQPGLHG-----IPGEKGDPGPPGLDVPGPPGERGSPGI 867



 Score = 47.4 bits (111), Expect = 4e-04
 Identities = 168/698 (24%), Positives = 247/698 (35%), Gaps = 144/698 (20%)

Query: 3500 KGDINIEGPSMNIEGPDLNVEGPEGGLKGPKFKMPDMNIKAPKISMPDIDLNLKGPKVKG 3559
            KGD   EGP      P +++ GP G          D    AP +  P       GP +  
Sbjct: 408  KGD---EGP------PGISIPGPPG---------LDGQPGAPGLPGPP---GPAGPHIPP 446

Query: 3560 DVDISLPKLEGDLKGP-------EVDIKGPKVD--INAPDVDVHGPDWHLKMPKVKMPKF 3610
              +I  P   G    P       E  +KG K D   N     + GP     +P +  P  
Sbjct: 447  SDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPG 506

Query: 3611 SM--PGFKGEGPEVDVTLPKADIDISGPNVDVDVPDVNIEGPDAK----LKGPKFKMPEM 3664
            S+  PG KGE  +   T PK    I G       P    E  D      +KG K ++   
Sbjct: 507  SLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSP 566

Query: 3665 NIKA----PKISMPDFDLNLKGPKMKGDVVV-----------SLPKVEGDLKGPEVDIKG 3709
                    P     D    L GPK +   +             LP + G++        G
Sbjct: 567  GAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFG 626

Query: 3710 PKVDIDTPDIN-IEGSEGK--FKGPKFKIPEMHLKAPKISMP-----DIDLNLKG-PKVK 3760
            P   +    I  + G+ G+    GPK    +   +  K  +P     D D+ L G P + 
Sbjct: 627  PPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP 686

Query: 3761 GDVDV-SLPKMEGDLKGPEVDIKGPKVDINAPDVD-------------VQGPDWHLKMPK 3806
            G   +  +P  +G+   P + + GP      P +              ++GP      P 
Sbjct: 687  GQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG 746

Query: 3807 VK-MPKFSMPG---------FKGE-GPDVDVNLP-------KADLD-VSGPKVDIDVPDV 3847
             K  P F++PG         FKG  GP  D   P       +  LD + GPK D+     
Sbjct: 747  PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV----- 801

Query: 3848 NIEGPEGKLKGPKFK--MPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMQVP 3905
               GP G+  GP     +P + ++ P    P I   +  P + G     +P  +GD   P
Sbjct: 802  ---GPNGQ-PGPMGPPGLPGIGVQGPP-GPPGIPGPIGQPGLHG-----IPGEKGDPGPP 851

Query: 3906 DLDIKGPKVDINAPDVDVR----GPDWHLKMPKIKMPKISMPGFKGEGPEVDVNLPKADL 3961
             LD+ GP  +  +P +       GP     +P  K      PG KGE   +    P   L
Sbjct: 852  GLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPG-KAGASGFPGTKGEMGMMGPPGPPGPL 910

Query: 3962 DVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDV 4021
             + G      VP   ++G D  L+G            P +  P  +   KG       + 
Sbjct: 911  GIPGRS---GVP--GLKGDDG-LQG-----------QPGLPGPTGEKGSKG-------EP 946

Query: 4022 SLPKMEGDLKAPEVDIKGPKVDIDAPDV-DVHGPDWHLKMP-KVKMPKFS-MPGFKG-EG 4077
             LP   G +    +  KG K +   P +  V GP  +  +P     P  S  PG  G  G
Sbjct: 947  GLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPG 1006

Query: 4078 PEVDVNLPKADIDVSGPKVDIDTPDIDIHGPEGKLKGP 4115
            P+ +  LP     +  P +     D+   GP+G ++GP
Sbjct: 1007 PKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQG-VEGP 1043



 Score = 47.0 bits (110), Expect = 6e-04
 Identities = 129/480 (26%), Positives = 165/480 (34%), Gaps = 80/480 (16%)

Query: 5242 GIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPD--VSLKGP-GVDLPSVNLSMPKVS 5298
            GIPG+K E G   + + LP  +G+   P     GP     L GP G+  P      P + 
Sbjct: 150  GIPGMKGEPGSI-IMSSLPGPKGNPGYP-----GPPGIQGLPGPTGIPGPIGPPGPPGLM 203

Query: 5299 GPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLSGVGGKMQVGGDGVK----VPGIDATT 5354
            GP     L GP  KG++            GLN  G  G+   G  G++     PG  +  
Sbjct: 204  GPPGPPGLPGP--KGNM------------GLNFQGPKGEK--GEQGLQGPPGPPGQISEQ 247

Query: 5355 KLNVGAP----DVTLRG-------PSLQGDLAVSGDIKCPKVSVGAPDL----SLEASEG 5399
            K  +       D  L G       P ++G     G  K  K   G P        +   G
Sbjct: 248  KRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENG 307

Query: 5400 SIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRIS-APNVDFNLEG 5458
               +P +         PG D     KG   +G    PG+ +   G  I+     +  L G
Sbjct: 308  QPGIPGLPGDPGYPGEPGRDGEKGQKGD--TGPPGPPGLVIPRPGTGITIGEKGNIGLPG 365

Query: 5459 -PKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQ 5517
             P  KG  G  G I+GP    G PG  V G  G    PG +    D   PG+++  P G 
Sbjct: 366  LPGEKGERGFPG-IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGL 424

Query: 5518 ISGPEIKG--GLKGSEVGFHGAAPDISVKGPAFNMASP--------------ESDFGINL 5561
               P   G  G  G        + +I   GP     SP              + D   N 
Sbjct: 425  DGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNC 484

Query: 5562 KGPKIKGGADVSG--GVSAPDISLG-EGHLSVKGSGGEW--KG----PQVSSALNLDTSK 5612
             G  I G     G  G+  P  SLG  G    KG  G    KG    P    A     SK
Sbjct: 485  IGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSK 544

Query: 5613 FAGG--LHFSGPKVEGGVKGGQIGLQAPGLSVSGPQGHLESGSGKVTFPKMKIPKFTFSG 5670
               G  L F G K + G  G       PGL  +  Q  L    G    PK +    TF G
Sbjct: 545  GEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPG----PKGEPGGITFKG 600



 Score = 42.4 bits (98), Expect = 0.014
 Identities = 164/684 (23%), Positives = 233/684 (34%), Gaps = 149/684 (21%)

Query: 291  VQGPSLESGDHGKIKFPTMKVPKFGVSTGREGQTPKAGLR-VSAPEVSVGHKG-----GK 344
            +QG     GD G   F         + TG  G   + GL  +  P  S+G  G     G+
Sbjct: 467  LQGEQGVKGDKGDTCFNC-------IGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQ 519

Query: 345  PGLTIQAPQLEVSVPSA----NIEGLEGKLKGPQITGPSLEGDLGLKGAK-PQGHIGVDA 399
             G T   P+    +P A       G +G+  G  +T P ++GD G  G+    G  G+  
Sbjct: 520  AGAT--GPKGLPGIPGAPGAPGFPGSKGE-PGDILTFPGMKGDKGELGSPGAPGLPGLPG 576

Query: 400  SAPQIG-GSITGPSVEV--------QAPDIDVQGPGSKLNVPKMKVPKFSVSGAKGEETG 450
            +  Q G   + GP  E         + P  +   PG   N+  M  P F   G  GE+  
Sbjct: 577  TPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGI 636

Query: 451  IDVTLPTGEVTVPGVSGD--VSLPEIATGGLEGKMKGTKVKTPEMIIQKPKISMQDVDLS 508
              V    G+  +PG  GD   ++ +    GL G                     +D D+ 
Sbjct: 637  QGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGN------------------PGRDGDVG 678

Query: 509  L-GSPKLKGDIKVSAPGVQGDVKGPQVALKGSRVDIETPNLEGTLTGPRLGSPSGKTGT- 566
            L G P L G  +   PG+ G    P +        I  P   G    P +  P G  GT 
Sbjct: 679  LPGDPGLPG--QPGLPGIPGSKGEPGIP------GIGLPGPPGPKGFPGIPGPPGAPGTP 730

Query: 567  CRISMSEVDLNVAAPKVKGGVDVTLPRVEGKVKVPEV-DVRGPKVDVSAPDVEAHGPEWN 625
             RI +         P  KG     LP   G   +P      GPK D   P     GP   
Sbjct: 731  GRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFP-----GP--- 782

Query: 626  LKMPKMKMPTFSTPGAKGEGPDVHMTLPKGDISISGPKVNVEAPDVNLEGLGGKLKGPDV 685
                         PG  G      +  PKGD+  +G    +  P   L G+G  ++GP  
Sbjct: 783  -------------PGPPGRTGLDGLPGPKGDVGPNGQPGPMGPP--GLPGIG--VQGPP- 824

Query: 686  KLPDMSVKTPKISMPDVDLHVKGTKVKGEYDVTVPKLEGELKGPKVDIDAPDVDVHGPDW 745
                     P I  P                +  P L G + G K D   P +DV GP  
Sbjct: 825  -------GPPGIPGP----------------IGQPGLHG-IPGEKGDPGPPGLDVPGPPG 860

Query: 746  HLKMPKMKMPKFSVPGFKAE-GPEVDVNLP-----------KADVDISGPKIDVTAPDVS 793
                P        +PG     GP     LP           K ++ + GP      P   
Sbjct: 861  ERGSP-------GIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP----PGPPGP 909

Query: 794  IEEPEGKLKGPKFKMPEMNIKVPKISMPDVDLHLKG-PNVKGEYDVTMPKVESEIKVPDV 852
            +  P G+   P  K  +     P +  P  +   KG P + G      P +        +
Sbjct: 910  LGIP-GRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNL--------L 960

Query: 853  ELKSAKMDIDVPDVE-VQGPDWHLKMP-KMKMPKFS-MPGFKA-EGPEVDVNLPKADVDI 908
              K  K +  +P +  V GP  +  +P     P  S  PG     GP+ +  LP     I
Sbjct: 961  GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI 1020

Query: 909  SGPKVGVEVPDVNIEGPEGKLKGP 932
              P +   + D+   GP+G ++GP
Sbjct: 1021 GPPGLKGTIGDMGFPGPQG-VEGP 1043



 Score = 42.4 bits (98), Expect = 0.014
 Identities = 276/1149 (24%), Positives = 397/1149 (34%), Gaps = 262/1149 (22%)

Query: 2025 IKGPKMD--IDAPDVDVHGPDWHLKMPKMKMPKFSM--PGFKAE-------GPEVDVNLP 2073
            +KG K D   +     + GP     +P +  P  S+  PG K E       GP+    +P
Sbjct: 473  VKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIP 532

Query: 2074 KADVVVSGPKVDVEVPDV----SLEGPEGKLKGPKLK-MPEMHFKAPKISMPDVDLHLKG 2128
             A      P    E  D+     ++G +G+L  P    +P +     +  +P     L G
Sbjct: 533  GAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPG----LPG 588

Query: 2129 PK-------VKGDV----DVSLPKLEGDL----------TGPSVDVEVPDVELECPDAKL 2167
            PK        KG+     +  LP L G++           GP  +  +  V        +
Sbjct: 589  PKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGI 648

Query: 2168 KGPKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMDV-SVPKVEGEMKVPDVDIRGPKVD 2226
             GPK    +   +  K  +P        P   GD+ +   P + G+  +P +   G K +
Sbjct: 649  PGPKGDPGQTITQPGKPGLPG------NPGRDGDVGLPGDPGLPGQPGLPGIP--GSKGE 700

Query: 2227 IDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKGEGPEVDVNLPKADVDVSGPKVDVEVPDV 2286
               P + + GP      P +  P    PG  G    + +  P       GPK +   P  
Sbjct: 701  PGIPGIGLPGPPGPKGFPGIPGP----PGAPGTPGRIGLEGPPGPPGFPGPKGE---PGF 753

Query: 2287 SLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVDVSAPK-------LEG 2339
            +L GP G    P FK                     GPK  GD     P        L+G
Sbjct: 754  ALPGPPGPPGLPGFK------------------GALGPK--GDRGFPGPPGPPGRTGLDG 793

Query: 2340 ELKGPELDV-----KGPKLDADMPEVAVEGPNGKWKTPKFKMPDMHFKAPKISMPDLDLH 2394
             L GP+ DV      GP     +P + V+GP G                P I  P     
Sbjct: 794  -LPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGP---------------PGIPGP----- 832

Query: 2395 LKSPKAKGEVDVDVPKLEGDLKGPHVDVSGPDIDIEGPEGKLKGPKFKMPDMHFKAPNIS 2454
                       +  P L G + G   D   P +D+ GP G+   P          AP   
Sbjct: 833  -----------IGQPGLHG-IPGEKGDPGPPGLDVPGPPGERGSPGIP------GAPGPI 874

Query: 2455 MPDVDLNLKG-------PKIKGDVD-VSVPEVEGKLEVPDMNIRGPKVDVNAPDVQAPDW 2506
             P     L G       P  KG++  +  P   G L +P  +          P ++  D 
Sbjct: 875  GPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRS--------GVPGLKGDDG 926

Query: 2507 HLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDIEGP-DVNIEGPEGKLKGP 2565
                P        +PG   E         K +  + GP     GP D N+ G +G+   P
Sbjct: 927  LQGQP-------GLPGPTGEKGS------KGEPGLPGP----PGPMDPNLLGSKGEKGEP 969

Query: 2566 KLKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGD--LKGPEVDIKGPKVDIN 2623
             L         P +S P     L G       D   P + G   L GP     GPK +  
Sbjct: 970  GLP------GIPGVSGPKGYQGLPG-------DPGQPGLSGQPGLPGP----PGPKGNPG 1012

Query: 2624 AP-DVGVQGPDWHLKMPKVK--MPKFSMPGFKG-EGPDGDVKLP--KADIDVSGPKVDIE 2677
             P   G+ GP      P +K  +     PG +G EGP G   +P       + G K D  
Sbjct: 1013 LPGQPGLIGP------PGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKG 1066

Query: 2678 GPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDV-DVSLPKVEG-- 2734
             P ++  G  G L GPK               P +      P +KG V D  LP + G  
Sbjct: 1067 DPGISSIGLPG-LPGPK-------------GEPGLPGYPGNPGIKGSVGDPGLPGLPGTP 1112

Query: 2735 DLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKIKMPKISMPGFKGE-GPDVDVNLPKA 2793
              KG       P          + GP  +  +P    P +   G  G+ GP  +   P  
Sbjct: 1113 GAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGP-VGGGGHPGQPGPPGEKGKPGQ 1171

Query: 2794 DIDVSGPKVDVECPDVNIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDV 2853
            D  + GP            G +G+   P F  P      P +S    D  L  P I G+ 
Sbjct: 1172 D-GIPGP-----------AGQKGEPGQPGFGNPGPP-GLPGLSGQKGDGGL--PGIPGNP 1216

Query: 2854 DVTGPKVEGDLKG-PEVDLKGPKVDIDVPDVNVQGPDWHLKMPKMKMPKFSMPGFKA-EG 2911
             + GPK E    G P V  +GP      P   ++GP  +   P+    +    GF+   G
Sbjct: 1217 GLPGPKGEPGFHGFPGV--QGPPGPPGSPGPALEGPKGN-PGPQGPPGRPGPTGFQGLPG 1273

Query: 2912 PEVDVNLPKADVDVSGPKVDVEGPDV-------NIEGPEGKLKGPKFKMPEMNIKA-PKI 2963
            PE    LP  +  + G K +   P +         +GP G L+G   +     +K  P +
Sbjct: 1274 PEGPPGLP-GNGGIKGEKGNPGQPGLPGLPGLKGDQGPPG-LQGNPGRPGLNGMKGDPGL 1331

Query: 2964 P-MPDFDLHLKGPKVKGDVDISLPKVEGDLKGP--EVDIRGPQ-----VDIDVPDVGVQG 3015
            P +P F   +KGP   G    + P+ E  L GP     + GP      +  D    G+ G
Sbjct: 1332 PGVPGFP-GMKGP--SGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPG 1388

Query: 3016 PDWHLKMPKVKMPKFSMPGFKGEGPDVDVN-LPKADLDVSGPKVDIDVPDV----NIEGP 3070
                  +P  + P+  +PG  G   D   N LP  D    G K D  +P       ++GP
Sbjct: 1389 QPGLKGLPGPQGPQ-GLPGPTGPPGDPGRNGLPGFD-GAGGRKGDPGLPGQPGTRGLDGP 1446

Query: 3071 EGK--LKGP 3077
             G   L+GP
Sbjct: 1447 PGPDGLQGP 1455



 Score = 38.1 bits (87), Expect = 0.26
 Identities = 254/1033 (24%), Positives = 358/1033 (34%), Gaps = 243/1033 (23%)

Query: 2939 IEGPEGKLKGPKFKMPEMNIKAPKIPMPDFDLHLKGPKVKGDVDISLPKVEGDLKGPEVD 2998
            ++GP G    P  K    +I    +P P  +    GP          P ++G L GP   
Sbjct: 142  LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGP----------PGIQG-LPGP-TG 189

Query: 2999 IRGPQVDIDVPDV-GVQGPDWHLKMPKVKMP-KFSMP-GFKGE-------GPDVDVNLPK 3048
            I GP      P + G  GP   L  PK  M   F  P G KGE       GP   ++  K
Sbjct: 190  IPGPIGPPGPPGLMGPPGPPG-LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQK 248

Query: 3049 ADLDVSGPKVDIDVPD-------VNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLK 3101
              +DV   K D  +P          I GP G   G K +  E   +  K   P  D    
Sbjct: 249  RPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQG-EPGKRGKPGKDGENG 307

Query: 3102 GPKVKGDMDVSLPKVEGDMKVPDVD-IKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISM 3160
             P + G     LP   G    P  D  KG K D   P     GP      P + +P+   
Sbjct: 308  QPGIPG-----LPGDPGYPGEPGRDGEKGQKGDTGPP-----GP------PGLVIPRPGT 351

Query: 3161 PGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKIS 3220
                GE  + ++ LP     + G K +   P   I+GP   L GP    P   +  P   
Sbjct: 352  GITIGE--KGNIGLP----GLPGEKGERGFP--GIQGPPG-LPGP----PGAAVMGPP-- 396

Query: 3221 MPDLDLNLKGPKMKGEVDVSLANVEGDLKGPALDIKGPK-IDVDAPDIDIHGPDAKLKGP 3279
                      P   GE        +GD   P + I GP  +D       + GP     GP
Sbjct: 397  --------GPPGFPGE-----RGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPA-GP 442

Query: 3280 KLKMPDMHVNMPKISMPEIDLNLKGSKLKGDVDVSGPKLEGDIKAPSLDIKGPEVDVSGP 3339
             +  P   +  P    P      KG  L+G+  V G K +         I GP      P
Sbjct: 443  HIP-PSDEICEPGPPGPPGSPGDKG--LQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLP 499

Query: 3340 KLNIEGKSKKSRFKLPKFNFSGSKVQTPEVDVKGKKPDIDITGPKVDINAPDVEVQGKVK 3399
             L     S           F G K         G+K     TGPK     P         
Sbjct: 500  GLPGPPGS---------LGFPGQK---------GEKGQAGATGPKGLPGIPGAPGAPGFP 541

Query: 3400 GSKFKMPFLSISSPKVSMPDVELNLKSPKVKGDLDIAGPNLEGDFKGPKVDIKAPEVNLN 3459
            GSK +                          GD+ +  P ++GD    K ++ +P     
Sbjct: 542  GSKGE-------------------------PGDI-LTFPGMKGD----KGELGSP----G 567

Query: 3460 APDVD-VHGPDWNLKMPKMKMPKFSVSGL--KAE-GPDVAVDLP--KGDINIEGP-SMNI 3512
            AP +  + G      +P +  PK    G+  K E GP     LP   G+I   GP     
Sbjct: 568  APGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGP 627

Query: 3513 EGP--DLNVEGPEG-----GLKGPKFKMPDMNIKAP-KISMP-----DIDLNLKG-PKVK 3558
             GP  +  ++G  G     G+ GPK   P   I  P K  +P     D D+ L G P + 
Sbjct: 628  PGPVGEKGIQGVAGNPGQPGIPGPKGD-PGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP 686

Query: 3559 GDVDI-SLPKLEGDLKGPEVDIKGPKVDINAPDVD-------------VHGPDWHLKMPK 3604
            G   +  +P  +G+   P + + GP      P +              + GP      P 
Sbjct: 687  GQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG 746

Query: 3605 VK-MPKFSMPG---------FKGE-GPEVDVTLP-------KADID-ISGPNVDVDVPDV 3645
             K  P F++PG         FKG  GP+ D   P       +  +D + GP  DV     
Sbjct: 747  PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV----- 801

Query: 3646 NIEGPDAKLKGPKFK--MPEMNIKAPKISMPDFDLNLKGPKMKGDVVVSLPKVEGDLKGP 3703
               GP+ +  GP     +P + ++ P    P     +  P + G     +P  +GD   P
Sbjct: 802  ---GPNGQ-PGPMGPPGLPGIGVQGPP-GPPGIPGPIGQPGLHG-----IPGEKGDPGPP 851

Query: 3704 EVDIKGPKVDIDTPDI----------NIEGSEGK-----FKGPKFKIPEMHLKAP----- 3743
             +D+ GP  +  +P I             G  GK     F G K ++  M    P     
Sbjct: 852  GLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLG 911

Query: 3744 ---KISMPDI--DLNLKG-PKVKGDVDVSLPKMEGDLKGPE-------VDIKGPKVDINA 3790
               +  +P +  D  L+G P + G       K E  L GP        +  KG K +   
Sbjct: 912  IPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGL 971

Query: 3791 PDV-DVQGPDWHLKMP-KVKMPKFS-MPGFKG-EGPDVDVNLPKADLDVSGPKVDIDVPD 3846
            P +  V GP  +  +P     P  S  PG  G  GP  +  LP     +  P +   + D
Sbjct: 972  PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGD 1031

Query: 3847 VNIEGPEGKLKGP 3859
            +   GP+G ++GP
Sbjct: 1032 MGFPGPQG-VEGP 1043



 Score = 37.0 bits (84), Expect = 0.58
 Identities = 202/844 (23%), Positives = 288/844 (34%), Gaps = 216/844 (25%)

Query: 3760 KGDVDV-SLPKMEGDLKGPEVDIKGPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFK 3818
            KG++ +  LP  +G+   P   I+GP      P   V GP                PGF 
Sbjct: 358  KGNIGLPGLPGEKGERGFP--GIQGPPGLPGPPGAAVMGPP-------------GPPGFP 402

Query: 3819 GEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDI 3878
            GE                G K D   P ++I GP G    P          AP +  P  
Sbjct: 403  GE---------------RGQKGDEGPPGISIPGPPGLDGQPG---------APGLPGPP- 437

Query: 3879 DLNLKGPKVKGDMDVSLPKVEGDMQVP-------DLDIKGPKVD--INAPDVDVRGPDWH 3929
                 GP +    ++  P   G    P       +  +KG K D   N     + GP   
Sbjct: 438  --GPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495

Query: 3930 LKMPKIKMP--KISMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGP 3987
              +P +  P   +  PG KGE         K     +GPK    +P      P A     
Sbjct: 496  PGLPGLPGPPGSLGFPGQKGE---------KGQAGATGPKGLPGIPGA----PGA----- 537

Query: 3988 KFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKVDIDAP 4047
                            P F      P   GD+ ++ P M+GD        KG      AP
Sbjct: 538  ----------------PGFPGSKGEP---GDI-LTFPGMKGD--------KGELGSPGAP 569

Query: 4048 DVD-VHGPDWHLKMPKVKMPKFSMPG--FKGE-GPEVDVNLP--KADIDVSGPKVDIDTP 4101
             +  + G      +P +  PK    G  FKGE GP  +  LP    +I   GP      P
Sbjct: 570  GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGP------P 623

Query: 4102 DIDIHGPEGK--------------LKGPKFKMPDLHLKAPKISMP-----EVDLNLKG-P 4141
                 GP G+              + GPK        +  K  +P     + D+ L G P
Sbjct: 624  GFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDP 683

Query: 4142 KMKGDVDV-SLPKVEGDLKGPEVDIKGPKVDIDVPDVD-------------VQGPDWHLK 4187
             + G   +  +P  +G+   P + + GP      P +              ++GP     
Sbjct: 684  GLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPG 743

Query: 4188 MPKVK-MPKFSMPG---------FKGE-GPDVDVNLP-------KADLD-VSGPKVDIDV 4228
             P  K  P F++PG         FKG  GP  D   P       +  LD + GPK D+  
Sbjct: 744  FPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV-- 801

Query: 4229 PDVNIEGPDAKLKGPKFK--MPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDL 4286
                  GP+ +  GP     +P + ++ P    P     +  P + G     +P  +GD 
Sbjct: 802  ------GPNGQ-PGPMGPPGLPGIGVQGPP-GPPGIPGPIGQPGLHG-----IPGEKGDP 848

Query: 4287 KGPEVDIKGPKVDIDAPDV----DVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVTLPK 4342
              P +D+ GP  +  +P +       GP     +P  K      PG KGE   +    P 
Sbjct: 849  GPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPG-KAGASGFPGTKGEMGMMGPPGPP 907

Query: 4343 ADIEISGPK-VDIDAPDVSIEGPDAKLKGP---KFKMPEMNIKAPKISMPDIDFNLKGPK 4398
              + I G   V     D  ++G    L GP   K    E  +  P   M   D NL G K
Sbjct: 908  GPLGIPGRSGVPGLKGDDGLQGQPG-LPGPTGEKGSKGEPGLPGPPGPM---DPNLLGSK 963

Query: 4399 -VKGDVDVSLPKVEGDLKGPEIDIKGPSLDIDTPDVN----IEGPEGKLKGPKFKMPEMN 4453
              KG  +  LP + G + GP+   +G   D   P ++    + GP G    P        
Sbjct: 964  GEKG--EPGLPGIPG-VSGPK-GYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGL 1019

Query: 4454 IKAPKISMPDFDLHLKGPK-VKGDVDVS----------LPKVESDLKGPEVDIEGPEGKL 4502
            I  P +     D+   GP+ V+G    S          LP  + D   P +   G  G L
Sbjct: 1020 IGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPG-L 1078

Query: 4503 KGPK 4506
             GPK
Sbjct: 1079 PGPK 1082


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score = 79.3 bits (194), Expect = 1e-13
 Identities = 179/638 (28%), Positives = 231/638 (36%), Gaps = 104/638 (16%)

Query: 5160 KGPKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPSVGLEG 5219
            KG K QA    P   + G+      P F  S  +    D+   L  P +KGD   +G  G
Sbjct: 514  KGEKGQAGATGPK-GLPGIPGAPGAPGFPGSKGEPG--DI---LTFPGMKGDKGELGSPG 567

Query: 5220 PD--VDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQ--------LPSLEGDLRGP 5269
                  L G   +   P       G+PG K E GG     +        LP L G++   
Sbjct: 568  APGLPGLPGTPGQDGLP-------GLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPM 620

Query: 5270 DVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGL 5329
                 GP   +   G+   + N   P + GP  D    G ++       +P        +
Sbjct: 621  GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGD---PGQTITQPGKPGLPGNPGRDGDV 677

Query: 5330 NLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGA 5389
             L G  G     G    +PGI  + K   G P + L GP   G     G I  P  + G 
Sbjct: 678  GLPGDPGLPGQPG----LPGIPGS-KGEPGIPGIGLPGPP--GPKGFPG-IPGPPGAPGT 729

Query: 5390 PD-LSLEASEGSIKLPKMK-LPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRI 5447
            P  + LE   G    P  K  P F +  P     +    P   G L GP  D    GP  
Sbjct: 730  PGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGL----PGFKGAL-GPKGDRGFPGP-- 782

Query: 5448 SAPNVDFNLEG-PKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMP---------GI 5497
              P     L+G P  KG +G  G+  GP    GLPGIGVQG  G   +P         GI
Sbjct: 783  PGPPGRTGLDGLPGPKGDVGPNGQ-PGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGI 841

Query: 5498 KSSGCDVNLPGVNVKLPTGQISGPEIKG-----------GL--KGSEVGFHGAAPDISVK 5544
                 D   PG++V  P G+   P I G           GL  K    GF G   ++ + 
Sbjct: 842  PGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMM 901

Query: 5545 GPAFNMASPESDFGINLKG--PKIKGGADVSGGVSAPDISLGEGHLSVKGSGGE-----W 5597
            GP      P    GI  +   P +KG   + G    P      G    KGS GE      
Sbjct: 902  GP----PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLP------GPTGEKGSKGEPGLPGP 951

Query: 5598 KGPQVSSALNLDTSKFAGGL----HFSGPKVEGGVKG--GQIGLQA-PGL-SVSGPQGH- 5648
             GP   + L     K   GL      SGPK   G+ G  GQ GL   PGL    GP+G+ 
Sbjct: 952  PGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNP 1011

Query: 5649 -LESGSGKVTFPKMK--IPKFTFSGRELVGREMGVDVHFPKAEASIQAGAGDGEWEESEV 5705
             L    G +  P +K  I    F G + V    G     P    S       G+  +  +
Sbjct: 1012 GLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPS-GVPGQPGSPGLPGQKGDKGDPGI 1070

Query: 5706 KLKKSKIKMPKFNFSKPKGKGGVTGSP-EASISGSKGD 5742
                S I +P      PKG+ G+ G P    I GS GD
Sbjct: 1071 ----SSIGLP--GLPGPKGEPGLPGYPGNPGIKGSVGD 1102



 Score = 67.0 bits (162), Expect = 5e-10
 Identities = 229/921 (24%), Positives = 316/921 (34%), Gaps = 191/921 (20%)

Query: 4663 PGFKGE-GPDVDVNLPKAD--------IDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPE 4713
            PG  G  G D DV LP             + G K +  +P + + GP     GPK     
Sbjct: 665  PGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPP----GPK----- 715

Query: 4714 MSIKAPKISMPDIDLNLKGPKVKGDVDVTLPKVEGDLKGPEADIKGPKVDINTPDVDVHG 4773
                      P I      P   G + +  P       GP+ +          P   + G
Sbjct: 716  --------GFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGE----------PGFALPG 757

Query: 4774 PDWHLKMPKVKMPKFSMPGFKGE-GPDVDVSLP-------KADID-VSGPKVDVDIPDVN 4824
            P               +PGFKG  GP  D   P       +  +D + GPK DV      
Sbjct: 758  PPGPP----------GLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV------ 801

Query: 4825 IEGPDAKLKGPKFK--MPEINIKAPKISIPDVDLDLKGPKVKGDFDVSVPKVEGTLKGPE 4882
              GP+ +  GP     +P I ++ P             P + G   +  P + G + G +
Sbjct: 802  --GPNGQ-PGPMGPPGLPGIGVQGPP----------GPPGIPGP--IGQPGLHG-IPGEK 845

Query: 4883 VDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLHLKAPKIGFSGPKLEGGEV 4942
             D   P LD  GP  +   P +      I  P        L  KA   GF G K   GE+
Sbjct: 846  GDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG----LPGKAGASGFPGTK---GEM 898

Query: 4943 DLKGPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKFGFGAKSPKADIKSPSLDVTVPE 5002
             + GP      L +   S    ++G D    +   P    G    K     P L      
Sbjct: 899  GMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLP----GPTGEKGSKGEPGLPGPPGP 954

Query: 5003 AELNLETPEISVGGKGKKSKFKMPKIH-MSGPKIKAKKQGFDLNVPGGEIDASLKAPDVD 5061
             + NL      +G KG+K +  +P I  +SGPK      G D   PG      L  P   
Sbjct: 955  MDPNL------LGSKGEKGEPGLPGIPGVSGPKGYQGLPG-DPGQPGLSGQPGLPGPPGP 1007

Query: 5062 VNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEFDIKSPKFKAEAPLP--SPKLEGELQA 5119
                 P    +  +  P   K   G M FP  +  ++ P   +  P    SP L G+   
Sbjct: 1008 KG--NPGLPGQPGLIGPPGLKGTIGDMGFPGPQ-GVEGPPGPSGVPGQPGSPGLPGQKG- 1063

Query: 5120 PDLELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGDLKGPKVQANLGAPDI----NI 5175
               +   P I   GL      P +  P  +  +P   G+   P ++ ++G P +      
Sbjct: 1064 ---DKGDPGISSIGL------PGLPGPKGEPGLPGYPGN---PGIKGSVGDPGLPGLPGT 1111

Query: 5176 EGLDAKVKTPSF----GISAPQ-VSIPDVNVNLKG----------------PKIKGDVPS 5214
             G   +   P F    G   P+ +S P  N  L G                P  KG    
Sbjct: 1112 PGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQ 1171

Query: 5215 VGLEGPDVDLQGPEAKIKFPKFSMP-KIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKL 5273
             G+ GP     G + +   P F  P   G+PG+  + G       LP + G+   P  K 
Sbjct: 1172 DGIPGP----AGQKGEPGQPGFGNPGPPGLPGLSGQKGDGG----LPGIPGNPGLPGPKG 1223

Query: 5274 EGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLSG 5333
            E        PG          P V GP       GP+L+G      P      PGL   G
Sbjct: 1224 E--------PGFH------GFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGL--PG 1267

Query: 5334 VGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRG-PSLQGDLA---VSGDIKCPKVSVGA 5389
              G   + G+G    GI    K N G P   L G P L+GD     + G+   P ++   
Sbjct: 1268 PEGPPGLPGNG----GIKGE-KGNPGQPG--LPGLPGLKGDQGPPGLQGNPGRPGLNGMK 1320

Query: 5390 PDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISA 5449
             D  L    G    P MK P      PGS       GP+    L GP     L GP   +
Sbjct: 1321 GDPGLPGVPG---FPGMKGPS---GVPGS------AGPEGEPGLIGPPGPPGLPGPSGQS 1368

Query: 5450 PNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPG-IGVQGLEGNLQMPGIKSSGCDVNLPG 5508
              +  +   P + G  G  G + GP    GLPG  G  G  G   +PG   +G     PG
Sbjct: 1369 IIIKGDAGPPGIPGQPGLKG-LPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPG 1427

Query: 5509 VNVKLPTGQISGPEIKGGLKG 5529
            +  +  T  + GP    GL+G
Sbjct: 1428 LPGQPGTRGLDGPPGPDGLQG 1448



 Score = 65.1 bits (157), Expect = 2e-09
 Identities = 139/512 (27%), Positives = 179/512 (34%), Gaps = 110/512 (21%)

Query: 5200 NVNLKG-PKIKGDVPSVGLEGPD-------VDLQGPEAKIKFPKFSMPK--IGIPGVKME 5249
            N+ L G P  KG+    G++GP          + GP     FP     K   G PG+ + 
Sbjct: 360  NIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIP 419

Query: 5250 GGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKG- 5308
            G         P L+G    P   L GP     GP +  PS  +  P   GP      KG 
Sbjct: 420  GP--------PGLDGQPGAPG--LPGPP-GPAGPHIP-PSDEICEPGPPGPPGSPGDKGL 467

Query: 5309 ---PSLKGD----------LDASVPSMKVHAPGL-------NLSGVGG-KMQVGGDGVK- 5346
                 +KGD             S P  +   PGL          G  G K Q G  G K 
Sbjct: 468  QGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKG 527

Query: 5347 VPGIDATTKL-----NVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDL-SLEASEGS 5400
            +PGI           + G P   L  P ++GD    G++  P    GAP L  L  + G 
Sbjct: 528  LPGIPGAPGAPGFPGSKGEPGDILTFPGMKGD---KGELGSP----GAPGLPGLPGTPGQ 580

Query: 5401 IKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAP---------- 5450
              LP +  P+     PG       +GP  +  L G   ++   GP    P          
Sbjct: 581  DGLPGLPGPK---GEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQ 637

Query: 5451 NVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGI----------GVQGLEGNLQMPGIKSS 5500
             V  N   P + G  G  G+        GLPG           G  GL G   +PGI  S
Sbjct: 638  GVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGS 697

Query: 5501 GCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGIN 5560
              +  +PG+ +  P G    P I G       G  G    I ++GP      P       
Sbjct: 698  KGEPGIPGIGLPGPPGPKGFPGIPG-----PPGAPGTPGRIGLEGPPGPPGFP------- 745

Query: 5561 LKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFS 5620
              GPK + G  + G    P +   +G L  KG  G    P       LD      GL   
Sbjct: 746  --GPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLD------GL--P 795

Query: 5621 GPKVEGGVKG-----GQIGLQAPGLSVSGPQG 5647
            GPK + G  G     G  GL  PG+ V GP G
Sbjct: 796  GPKGDVGPNGQPGPMGPPGL--PGIGVQGPPG 825



 Score = 60.8 bits (146), Expect = 4e-08
 Identities = 257/1045 (24%), Positives = 349/1045 (33%), Gaps = 198/1045 (18%)

Query: 4664 GFKGEGPDVDVNLPKADIDVSGPKVDVDVPDVNIEGPDAKL--KGPKFKMPEMSIKAPKI 4721
            G KG+  D   N       +SGP     +P   + GP   L   G K +  +     PK 
Sbjct: 472  GVKGDKGDTCFNC--IGTGISGPPGQPGLP--GLPGPPGSLGFPGQKGEKGQAGATGPK- 526

Query: 4722 SMPDIDLNLKGPKVKGDVDVTLPKVEGDLKGPEADI------KGPKVDINTPDVD----V 4771
             +P I      P   G             KG   DI      KG K ++ +P       +
Sbjct: 527  GLPGIPGAPGAPGFPGS------------KGEPGDILTFPGMKGDKGELGSPGAPGLPGL 574

Query: 4772 HGPDWHLKMPKVKMPKFSMPG--FKGE-GPDVDVSLPKADIDVS----------GPKVDV 4818
             G      +P +  PK    G  FKGE GP  +  LP    ++           GP  + 
Sbjct: 575  PGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEK 634

Query: 4819 DIPDVNIEGPDAKLKGPKFKMPEINIKAPKISIP-----DVDLDLKG-PKVKGDFDVSVP 4872
             I  V        + GPK    +   +  K  +P     D D+ L G P + G     +P
Sbjct: 635  GIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQ--PGLP 692

Query: 4873 KVEGTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLHLKAPKIGF 4932
             + G+   P +    P +   GP      P +  P      P              +IG 
Sbjct: 693  GIPGSKGEPGI----PGIGLPGPPGPKGFPGIPGPPGAPGTPG-------------RIGL 735

Query: 4933 SGPKLEGGEVDLKGPKVEAPSLDVHMDSPDINIEGPDVK--IPKFKKPKFGFGAKSPKAD 4990
             GP    G     GPK E          P   + GP     +P FK      GA  PK D
Sbjct: 736  EGPP---GPPGFPGPKGE----------PGFALPGPPGPPGLPGFK------GALGPKGD 776

Query: 4991 IKSPSLDVTVPEAELN-LETPEISVGGKGKKSKFKMPKIHMSGPKIKAKKQGFDLNVPGG 5049
               P          L+ L  P+  VG  G+      P +    P I  +       +PG 
Sbjct: 777  RGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGL----PGIGVQGPPGPPGIPGP 832

Query: 5050 EIDASLKAPDVDVNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEFDIKSPKFKAEAPLP 5109
                 L     +    GP     +DV  P  ++   G    P       SP    +A   
Sbjct: 833  IGQPGLHGIPGEKGDPGPPG---LDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS 889

Query: 5110 S-PKLEGEL-----QAPDLELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGDL--KG 5161
              P  +GE+       P   L +P         ++  P +K  D     P + G    KG
Sbjct: 890  GFPGTKGEMGMMGPPGPPGPLGIPG--------RSGVPGLKGDDGLQGQPGLPGPTGEKG 941

Query: 5162 PKVQANLGAP----DINIEGLDAKVKTPSF----GISAP-----------------QVSI 5196
             K +  L  P    D N+ G   +   P      G+S P                 Q  +
Sbjct: 942  SKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGL 1001

Query: 5197 PDV-----NVNLKG-------PKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIP 5244
            P       N  L G       P +KG +  +G  GP   ++GP      P       G+P
Sbjct: 1002 PGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQ-GVEGPPGPSGVPG-QPGSPGLP 1059

Query: 5245 GVKMEGGGAEVHA-QLPSLEGDLRGPDVKLEGPDVSLKGPGVD--LPSVNLSMPKVSGPD 5301
            G K + G   + +  LP L G    P +     +  +KG   D  LP +  +      P 
Sbjct: 1060 GQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPG 1119

Query: 5302 LDLNLKGPSLKGDLDASVPSMKVHAPGLN--LSGVGGKMQVGGDGVK-VPGID-----AT 5353
            L      P   G    S P      PG    + G G   Q G  G K  PG D     A 
Sbjct: 1120 LPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAG 1179

Query: 5354 TKLNVGAPDVTLRGP-SLQGDLAVSGDIKCPKVSVGAPDLSLEASE-GSIKLPKMKLPQF 5411
             K   G P     GP  L G     GD   P +  G P L     E G    P ++ P  
Sbjct: 1180 QKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIP-GNPGLPGPKGEPGFHGFPGVQGPPG 1238

Query: 5412 GISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPK-VKGSLGATGE 5470
               +PG  L    +GP+ +   +GP     L GP           EGP  + G+ G  GE
Sbjct: 1239 PPGSPGPAL----EGPKGNPGPQGPPGRPGLPGP-----------EGPPGLPGNGGIKGE 1283

Query: 5471 IKGPTVGG--GLPGI----GVQGLEGNLQMPGIKSSGCDVNLPGV----NVKLPTG--QI 5518
               P   G  GLPG+    G  GL+GN   PG+     D  LPGV     +K P+G    
Sbjct: 1284 KGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGS 1343

Query: 5519 SGPEIKGGLKG--SEVGFHG-AAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGG 5575
            +GPE + GL G     G  G +   I +KG A     P       L GP  +G   + G 
Sbjct: 1344 AGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGP--QGPQGLPGP 1401

Query: 5576 VSAPDISLGEGHLSVKGSGGEWKGP 5600
               P      G     G+GG    P
Sbjct: 1402 TGPPGDPGRNGLPGFDGAGGRKGDP 1426



 Score = 55.5 bits (132), Expect = 2e-06
 Identities = 142/508 (27%), Positives = 191/508 (37%), Gaps = 81/508 (15%)

Query: 209  PSGSGAASPTGSAVDIRAGAISASGPELQGA-GHSKLQVTMPGIKVGGSGVNVNAKGLDL 267
            P G G   P G    I+  A +   P + G  G     +T PG K G  G N    G D+
Sbjct: 622  PPGFGPPGPVGEK-GIQGVAGNPGQPGIPGPKGDPGQTITQPG-KPGLPG-NPGRDG-DV 677

Query: 268  GGRGGVQVPAVDISSSLGGRAVEVQGPSLE-SGDHGKIKFPTMKVPKFGVSTGREGQTPK 326
            G  G   +P       + G   E   P +   G  G   FP +  P      G  G   +
Sbjct: 678  GLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPP-----GAPGTPGR 732

Query: 327  AGLRVSAPEVSVGHKG--GKPGLTIQAPQLEVSVPSANIEGLEGKLKGPQITGPSLEGDL 384
             GL    P    G  G  G+PG  +  P     +P     G +G L      GP  +GD 
Sbjct: 733  IGLE--GPPGPPGFPGPKGEPGFALPGPPGPPGLP-----GFKGAL------GP--KGDR 777

Query: 385  GLKGAK-PQGHIGVDASAPQIGGSI-----TGPSVEVQAPDIDVQGPGSKLNVPKM--KV 436
            G  G   P G  G+D   P   G +      GP      P I VQGP     +P    + 
Sbjct: 778  GFPGPPGPPGRTGLDG-LPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQP 836

Query: 437  PKFSVSGAKGEE--TGIDVTLPTGE---VTVPGVSGDVSLPEIATGGLEGK-----MKGT 486
                + G KG+    G+DV  P GE     +PG  G +  P   + GL GK       GT
Sbjct: 837  GLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPP--GSPGLPGKAGASGFPGT 894

Query: 487  KVKTPEMIIQKPKISMQDVDLSLGSPKLKGDIKVSAPGVQGD--VKGPQVALKGSRVDIE 544
            K +   M    P   +  +    G P LKGD      G+QG   + GP    KGS+ +  
Sbjct: 895  KGEMGMMGPPGPPGPL-GIPGRSGVPGLKGD-----DGLQGQPGLPGP-TGEKGSKGEPG 947

Query: 545  TPNLEGTLTGPRLGS--PSGKTGTCRISMSEVDLNVAAPKVKGGV--DVTLPRVEGKVKV 600
             P   G +    LGS    G+ G   I        V+ PK   G+  D   P + G+  +
Sbjct: 948  LPGPPGPMDPNLLGSKGEKGEPGLPGIP------GVSGPKGYQGLPGDPGQPGLSGQPGL 1001

Query: 601  PEVDVRGPKVDVSAPDVEAHGPEWNLKMPKMK--MPTFSTPGAKG-EGPDVHMTLP--KG 655
            P     GPK +   P     G    +  P +K  +     PG +G EGP     +P   G
Sbjct: 1002 P--GPPGPKGNPGLP-----GQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPG 1054

Query: 656  DISISGPKVNVEAPDVNLEGLGGKLKGP 683
               + G K +   P ++  GL G L GP
Sbjct: 1055 SPGLPGQKGDKGDPGISSIGLPG-LPGP 1081



 Score = 54.3 bits (129), Expect = 4e-06
 Identities = 224/889 (25%), Positives = 316/889 (35%), Gaps = 167/889 (18%)

Query: 2489 IRGPKVDVNAPDVQAPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDI 2548
            ++GP      P ++     + M  +  PK + PG+   GP     LP     I GP +  
Sbjct: 142  LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGN-PGYP--GPPGIQGLP-GPTGIPGP-IGP 196

Query: 2549 EGPDVNIEGPEGK--LKGPKLKMPEMNIKAPKISMPDFDLHLKGP--------KVKGDVD 2598
             GP   + GP G   L GPK  M  +N + PK    +  L  +GP        + K  +D
Sbjct: 197  PGPP-GLMGPPGPPGLPGPKGNMG-LNFQGPKGEKGEQGL--QGPPGPPGQISEQKRPID 252

Query: 2599 VSLPKVEGDLKG---------------PEVDIKGPKVDINAPDV-GVQGPDWHLKMPKVK 2642
            V   K +  L G               P    KG K +   P   G  G D     P + 
Sbjct: 253  VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312

Query: 2643 -MPKFSMPGFKGE-GPDGDVKLPKADIDVSGPK-VDIEGPDVNIE-GPEGKLKGPKFKMP 2698
             +P    PG+ GE G DG+ K  K D    GP  + I  P   I  G +G +  P     
Sbjct: 313  GLP--GDPGYPGEPGRDGE-KGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE 369

Query: 2699 EMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPK-------VEGDLKGPEVDIKGPK-VDI 2750
            +     P I  P     L GP     +    P         +GD   P + I GP  +D 
Sbjct: 370  KGERGFPGIQGPP---GLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG 426

Query: 2751 DAPDVDVHGPDWHLKMPKIKMPKISMPGFKGE-GPDVDVNLPKADIDVSGPKVDV--ECP 2807
                  + GP            +I  PG  G  G   D  L + +  V G K D    C 
Sbjct: 427  QPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGL-QGEQGVKGDKGDTCFNCI 485

Query: 2808 DVNIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPK-IKGDVDVTGPKVEGDLKG 2866
               I GP G+   P    P      P           TGPK + G     G       KG
Sbjct: 486  GTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKG 545

Query: 2867 PEVDL------KGPKVDIDVPDV----NVQGPDWHLKMPKMKMPKFSMPG--FKAE-GPE 2913
               D+      KG K ++  P       + G      +P +  PK    G  FK E GP 
Sbjct: 546  EPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPP 605

Query: 2914 VDVNLPKADVDVSG---PKVDVEGP--DVNIEGPEGK-----LKGPKFKMPEMNIKAPKI 2963
             +  LP    ++     P     GP  +  I+G  G      + GPK   P   I  P  
Sbjct: 606  GNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGD-PGQTITQPGK 664

Query: 2964 P-MP-----DFDLHLKG-PKVKGDVDI-SLPKVEGDLKGPEVDIRGPQVDIDVPDV---- 3011
            P +P     D D+ L G P + G   +  +P  +G+   P + + GP      P +    
Sbjct: 665  PGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPP 724

Query: 3012 ---------GVQGPDWHLKMPKVK-MPKFSMPG---------FKGE-GPDVDVNLP---- 3047
                     G++GP      P  K  P F++PG         FKG  GP  D   P    
Sbjct: 725  GAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPG 784

Query: 3048 ---KADLD-VSGPKVDIDVPDVNIEGPEGKLKGPKFK--MPEMNIKAPKISMPDIDLNLK 3101
               +  LD + GPK D+        GP G+  GP     +P + ++ P    P I   + 
Sbjct: 785  PPGRTGLDGLPGPKGDV--------GPNGQ-PGPMGPPGLPGIGVQGPP-GPPGIPGPIG 834

Query: 3102 GPKVKGDMDVSLPKVEGDMKVPDVDIKGPKVDINAPDV-DVQGPDWHLKMPKI--KMPKI 3158
             P + G     +P  +GD   P +D+ GP  +  +P +    GP      P +  K    
Sbjct: 835  QPGLHG-----IPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS 889

Query: 3159 SMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPK 3218
              PG KGE   +    P   L + G      VP   ++G D  L+G            P 
Sbjct: 890  GFPGTKGEMGMMGPPGPPGPLGIPGRS---GVP--GLKGDDG-LQG-----------QPG 932

Query: 3219 ISMPDLDLNLKG----PKMKGEVDVSLANVEGDLKGPAL----DIKGPK 3259
            +  P  +   KG    P   G +D +L   +G+   P L     + GPK
Sbjct: 933  LPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPK 981



 Score = 51.2 bits (121), Expect = 3e-05
 Identities = 199/836 (23%), Positives = 285/836 (34%), Gaps = 207/836 (24%)

Query: 2520 MPGFKAEGPEVDVNL---PKADVDISGPK--VDIEGPDVNIEGPEGKLKGPKLKMPE--M 2572
            +PG K E   + ++    PK +    GP     + GP   I GP G    P L  P    
Sbjct: 151  IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGP-TGIPGPIGPPGPPGLMGPPGPP 209

Query: 2573 NIKAPKISMPDFDLHLKGPK-VKGDVDVSLPKVE----GDLKGPEVDIKGPKVDINAP-D 2626
             +  PK +M    L+ +GPK  KG+  +  P        + K P +D++  K D   P D
Sbjct: 210  GLPGPKGNM---GLNFQGPKGEKGEQGLQGPPGPPGQISEQKRP-IDVEFQKGDQGLPGD 265

Query: 2627 VGVQGPDWHLKMPKVKMPKFSMPGFKGE----GPDGDVKLPKADIDVSGPKVDIEGPDVN 2682
             G  GP      P ++ P     G KGE    G  G    P  D +   P +     D  
Sbjct: 266  RGPPGP------PGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPG 319

Query: 2683 IEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKV----KGDVDV-SLPKVEGDLK 2737
              G  G+  G K +  +     P    P + +   G  +    KG++ +  LP  +G+  
Sbjct: 320  YPGEPGR-DGEKGQKGDTGPPGP----PGLVIPRPGTGITIGEKGNIGLPGLPGEKGERG 374

Query: 2738 GPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKADIDV 2797
             P   I+GP      P   V GP                PGF GE               
Sbjct: 375  FP--GIQGPPGLPGPPGAAVMGPP-------------GPPGFPGE--------------- 404

Query: 2798 SGPKVDVECPDVNIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTG 2857
             G K D   P ++I GP G    P           P +  P       GP I    ++  
Sbjct: 405  RGQKGDEGPPGISIPGPPGLDGQPG---------APGLPGPP---GPAGPHIPPSDEICE 452

Query: 2858 PKVEGDLKGP-------EVDLKGPKVD--IDVPDVNVQGPDWHLKMPKMKMPKFSM--PG 2906
            P   G    P       E  +KG K D   +     + GP     +P +  P  S+  PG
Sbjct: 453  PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG 512

Query: 2907 FKAEGPEVDVNLPKADVDVSG-------PKVDVEGPDV----NIEGPEGKLKGPKFK-MP 2954
             K E  +     PK    + G       P    E  D+     ++G +G+L  P    +P
Sbjct: 513  QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572

Query: 2955 EMNIKAPKIPMPDFDLHLKGPKVK-GDVDIS-------------LPKVEGDLKGPEVDIR 3000
             +    P  P  D    L GPK + G +                LP   G +  P     
Sbjct: 573  GL----PGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPP 628

Query: 3001 GPQVDIDVPDVGVQGPDWHLKMPKVKMPK------FSMPGFKG----EGPDVDVNLPKAD 3050
            GP     V + G+QG   +   P +  PK       + PG  G     G D DV LP   
Sbjct: 629  GP-----VGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDP 683

Query: 3051 --------LDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKG 3102
                      + G K +  +P + + GP G    P    P      P        + L+G
Sbjct: 684  GLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPG------RIGLEG 737

Query: 3103 PKVKGDMDVSLPKVEGDMKVPDVDIKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISMPG 3162
            P          P   G    P   + GP            GP               +PG
Sbjct: 738  PP-------GPPGFPGPKGEPGFALPGPP-----------GPP-------------GLPG 766

Query: 3163 FKGE-GPEVDVNLP-------KADLD-VSGPKVDVDVPDVNIEGPDAKLKGPKFK--MPE 3211
            FKG  GP+ D   P       +  LD + GPK DV        GP+ +  GP     +P 
Sbjct: 767  FKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV--------GPNGQ-PGPMGPPGLPG 817

Query: 3212 MNIKAPKISMPDLDLNLKGPKMKGEVDVSLANVEGDLKGPALDIKGPKIDVDAPDI 3267
            + ++ P    P +   +  P + G     +   +GD   P LD+ GP  +  +P I
Sbjct: 818  IGVQGPP-GPPGIPGPIGQPGLHG-----IPGEKGDPGPPGLDVPGPPGERGSPGI 867



 Score = 47.4 bits (111), Expect = 4e-04
 Identities = 168/698 (24%), Positives = 247/698 (35%), Gaps = 144/698 (20%)

Query: 3500 KGDINIEGPSMNIEGPDLNVEGPEGGLKGPKFKMPDMNIKAPKISMPDIDLNLKGPKVKG 3559
            KGD   EGP      P +++ GP G          D    AP +  P       GP +  
Sbjct: 408  KGD---EGP------PGISIPGPPG---------LDGQPGAPGLPGPP---GPAGPHIPP 446

Query: 3560 DVDISLPKLEGDLKGP-------EVDIKGPKVD--INAPDVDVHGPDWHLKMPKVKMPKF 3610
              +I  P   G    P       E  +KG K D   N     + GP     +P +  P  
Sbjct: 447  SDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPG 506

Query: 3611 SM--PGFKGEGPEVDVTLPKADIDISGPNVDVDVPDVNIEGPDAK----LKGPKFKMPEM 3664
            S+  PG KGE  +   T PK    I G       P    E  D      +KG K ++   
Sbjct: 507  SLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSP 566

Query: 3665 NIKA----PKISMPDFDLNLKGPKMKGDVVV-----------SLPKVEGDLKGPEVDIKG 3709
                    P     D    L GPK +   +             LP + G++        G
Sbjct: 567  GAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFG 626

Query: 3710 PKVDIDTPDIN-IEGSEGK--FKGPKFKIPEMHLKAPKISMP-----DIDLNLKG-PKVK 3760
            P   +    I  + G+ G+    GPK    +   +  K  +P     D D+ L G P + 
Sbjct: 627  PPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP 686

Query: 3761 GDVDV-SLPKMEGDLKGPEVDIKGPKVDINAPDVD-------------VQGPDWHLKMPK 3806
            G   +  +P  +G+   P + + GP      P +              ++GP      P 
Sbjct: 687  GQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG 746

Query: 3807 VK-MPKFSMPG---------FKGE-GPDVDVNLP-------KADLD-VSGPKVDIDVPDV 3847
             K  P F++PG         FKG  GP  D   P       +  LD + GPK D+     
Sbjct: 747  PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV----- 801

Query: 3848 NIEGPEGKLKGPKFK--MPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMQVP 3905
               GP G+  GP     +P + ++ P    P I   +  P + G     +P  +GD   P
Sbjct: 802  ---GPNGQ-PGPMGPPGLPGIGVQGPP-GPPGIPGPIGQPGLHG-----IPGEKGDPGPP 851

Query: 3906 DLDIKGPKVDINAPDVDVR----GPDWHLKMPKIKMPKISMPGFKGEGPEVDVNLPKADL 3961
             LD+ GP  +  +P +       GP     +P  K      PG KGE   +    P   L
Sbjct: 852  GLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPG-KAGASGFPGTKGEMGMMGPPGPPGPL 910

Query: 3962 DVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDV 4021
             + G      VP   ++G D  L+G            P +  P  +   KG       + 
Sbjct: 911  GIPGRS---GVP--GLKGDDG-LQG-----------QPGLPGPTGEKGSKG-------EP 946

Query: 4022 SLPKMEGDLKAPEVDIKGPKVDIDAPDV-DVHGPDWHLKMP-KVKMPKFS-MPGFKG-EG 4077
             LP   G +    +  KG K +   P +  V GP  +  +P     P  S  PG  G  G
Sbjct: 947  GLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPG 1006

Query: 4078 PEVDVNLPKADIDVSGPKVDIDTPDIDIHGPEGKLKGP 4115
            P+ +  LP     +  P +     D+   GP+G ++GP
Sbjct: 1007 PKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQG-VEGP 1043



 Score = 47.0 bits (110), Expect = 6e-04
 Identities = 129/480 (26%), Positives = 165/480 (34%), Gaps = 80/480 (16%)

Query: 5242 GIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPD--VSLKGP-GVDLPSVNLSMPKVS 5298
            GIPG+K E G   + + LP  +G+   P     GP     L GP G+  P      P + 
Sbjct: 150  GIPGMKGEPGSI-IMSSLPGPKGNPGYP-----GPPGIQGLPGPTGIPGPIGPPGPPGLM 203

Query: 5299 GPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLSGVGGKMQVGGDGVK----VPGIDATT 5354
            GP     L GP  KG++            GLN  G  G+   G  G++     PG  +  
Sbjct: 204  GPPGPPGLPGP--KGNM------------GLNFQGPKGEK--GEQGLQGPPGPPGQISEQ 247

Query: 5355 KLNVGAP----DVTLRG-------PSLQGDLAVSGDIKCPKVSVGAPDL----SLEASEG 5399
            K  +       D  L G       P ++G     G  K  K   G P        +   G
Sbjct: 248  KRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENG 307

Query: 5400 SIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRIS-APNVDFNLEG 5458
               +P +         PG D     KG   +G    PG+ +   G  I+     +  L G
Sbjct: 308  QPGIPGLPGDPGYPGEPGRDGEKGQKGD--TGPPGPPGLVIPRPGTGITIGEKGNIGLPG 365

Query: 5459 -PKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQ 5517
             P  KG  G  G I+GP    G PG  V G  G    PG +    D   PG+++  P G 
Sbjct: 366  LPGEKGERGFPG-IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGL 424

Query: 5518 ISGPEIKG--GLKGSEVGFHGAAPDISVKGPAFNMASP--------------ESDFGINL 5561
               P   G  G  G        + +I   GP     SP              + D   N 
Sbjct: 425  DGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNC 484

Query: 5562 KGPKIKGGADVSG--GVSAPDISLG-EGHLSVKGSGGEW--KG----PQVSSALNLDTSK 5612
             G  I G     G  G+  P  SLG  G    KG  G    KG    P    A     SK
Sbjct: 485  IGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSK 544

Query: 5613 FAGG--LHFSGPKVEGGVKGGQIGLQAPGLSVSGPQGHLESGSGKVTFPKMKIPKFTFSG 5670
               G  L F G K + G  G       PGL  +  Q  L    G    PK +    TF G
Sbjct: 545  GEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPG----PKGEPGGITFKG 600



 Score = 42.4 bits (98), Expect = 0.014
 Identities = 164/684 (23%), Positives = 233/684 (34%), Gaps = 149/684 (21%)

Query: 291  VQGPSLESGDHGKIKFPTMKVPKFGVSTGREGQTPKAGLR-VSAPEVSVGHKG-----GK 344
            +QG     GD G   F         + TG  G   + GL  +  P  S+G  G     G+
Sbjct: 467  LQGEQGVKGDKGDTCFNC-------IGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQ 519

Query: 345  PGLTIQAPQLEVSVPSA----NIEGLEGKLKGPQITGPSLEGDLGLKGAK-PQGHIGVDA 399
             G T   P+    +P A       G +G+  G  +T P ++GD G  G+    G  G+  
Sbjct: 520  AGAT--GPKGLPGIPGAPGAPGFPGSKGE-PGDILTFPGMKGDKGELGSPGAPGLPGLPG 576

Query: 400  SAPQIG-GSITGPSVEV--------QAPDIDVQGPGSKLNVPKMKVPKFSVSGAKGEETG 450
            +  Q G   + GP  E         + P  +   PG   N+  M  P F   G  GE+  
Sbjct: 577  TPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGI 636

Query: 451  IDVTLPTGEVTVPGVSGD--VSLPEIATGGLEGKMKGTKVKTPEMIIQKPKISMQDVDLS 508
              V    G+  +PG  GD   ++ +    GL G                     +D D+ 
Sbjct: 637  QGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGN------------------PGRDGDVG 678

Query: 509  L-GSPKLKGDIKVSAPGVQGDVKGPQVALKGSRVDIETPNLEGTLTGPRLGSPSGKTGT- 566
            L G P L G  +   PG+ G    P +        I  P   G    P +  P G  GT 
Sbjct: 679  LPGDPGLPG--QPGLPGIPGSKGEPGIP------GIGLPGPPGPKGFPGIPGPPGAPGTP 730

Query: 567  CRISMSEVDLNVAAPKVKGGVDVTLPRVEGKVKVPEV-DVRGPKVDVSAPDVEAHGPEWN 625
             RI +         P  KG     LP   G   +P      GPK D   P     GP   
Sbjct: 731  GRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFP-----GP--- 782

Query: 626  LKMPKMKMPTFSTPGAKGEGPDVHMTLPKGDISISGPKVNVEAPDVNLEGLGGKLKGPDV 685
                         PG  G      +  PKGD+  +G    +  P   L G+G  ++GP  
Sbjct: 783  -------------PGPPGRTGLDGLPGPKGDVGPNGQPGPMGPP--GLPGIG--VQGPP- 824

Query: 686  KLPDMSVKTPKISMPDVDLHVKGTKVKGEYDVTVPKLEGELKGPKVDIDAPDVDVHGPDW 745
                     P I  P                +  P L G + G K D   P +DV GP  
Sbjct: 825  -------GPPGIPGP----------------IGQPGLHG-IPGEKGDPGPPGLDVPGPPG 860

Query: 746  HLKMPKMKMPKFSVPGFKAE-GPEVDVNLP-----------KADVDISGPKIDVTAPDVS 793
                P        +PG     GP     LP           K ++ + GP      P   
Sbjct: 861  ERGSP-------GIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP----PGPPGP 909

Query: 794  IEEPEGKLKGPKFKMPEMNIKVPKISMPDVDLHLKG-PNVKGEYDVTMPKVESEIKVPDV 852
            +  P G+   P  K  +     P +  P  +   KG P + G      P +        +
Sbjct: 910  LGIP-GRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNL--------L 960

Query: 853  ELKSAKMDIDVPDVE-VQGPDWHLKMP-KMKMPKFS-MPGFKA-EGPEVDVNLPKADVDI 908
              K  K +  +P +  V GP  +  +P     P  S  PG     GP+ +  LP     I
Sbjct: 961  GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI 1020

Query: 909  SGPKVGVEVPDVNIEGPEGKLKGP 932
              P +   + D+   GP+G ++GP
Sbjct: 1021 GPPGLKGTIGDMGFPGPQG-VEGP 1043



 Score = 42.4 bits (98), Expect = 0.014
 Identities = 277/1148 (24%), Positives = 396/1148 (34%), Gaps = 266/1148 (23%)

Query: 2025 IKGPKMD--IDAPDVDVHGPDWHLKMPKMKMPKFSM--PGFKAE-------GPEVDVNLP 2073
            +KG K D   +     + GP     +P +  P  S+  PG K E       GP+    +P
Sbjct: 473  VKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIP 532

Query: 2074 KADVVVSGPKVDVEVPDV----SLEGPEGKLKGPKLK-MPEMHFKAPKISMPDVDLHLKG 2128
             A      P    E  D+     ++G +G+L  P    +P +     +  +P     L G
Sbjct: 533  GAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPG----LPG 588

Query: 2129 PK-------VKGDV----DVSLPKLEGDL----------TGPSVDVEVPDVELECPDAKL 2167
            PK        KG+     +  LP L G++           GP  +  +  V        +
Sbjct: 589  PKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGI 648

Query: 2168 KGPKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMDV-SVPKVEGEMKVPDVDIRGPKVD 2226
             GPK    +   +  K  +P        P   GD+ +   P + G+  +P +   G K +
Sbjct: 649  PGPKGDPGQTITQPGKPGLPG------NPGRDGDVGLPGDPGLPGQPGLPGIP--GSKGE 700

Query: 2227 IDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKGEGPEVDVNLPKADVDVSGPKVDVEVPDV 2286
               P + + GP      P +  P    PG  G    + +  P       GPK +   P  
Sbjct: 701  PGIPGIGLPGPPGPKGFPGIPGP----PGAPGTPGRIGLEGPPGPPGFPGPKGE---PGF 753

Query: 2287 SLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVDVSAPK-------LEG 2339
            +L GP G    P FK                     GPK  GD     P        L+G
Sbjct: 754  ALPGPPGPPGLPGFK------------------GALGPK--GDRGFPGPPGPPGRTGLDG 793

Query: 2340 ELKGPELDV-----KGPKLDADMPEVAVEGPNGKWKTPKFKMPDMHFKAPKISMPDLDLH 2394
             L GP+ DV      GP     +P + V+GP G                P I  P     
Sbjct: 794  -LPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGP---------------PGIPGP----- 832

Query: 2395 LKSPKAKGEVDVDVPKLEGDLKGPHVDVSGPDIDIEGPEGKLKGPKFKMPDMHFKAPNIS 2454
                       +  P L G + G   D   P +D+ GP G+   P          AP   
Sbjct: 833  -----------IGQPGLHG-IPGEKGDPGPPGLDVPGPPGERGSPGIP------GAPGPI 874

Query: 2455 MPDVDLNLKG-------PKIKGDVD-VSVPEVEGKLEVPDMNIRGPKVDVNAPDVQAPDW 2506
             P     L G       P  KG++  +  P   G L +P  +          P ++  D 
Sbjct: 875  GPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRS--------GVPGLKGDDG 926

Query: 2507 HLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDIEGP-DVNIEGPEGKLKGP 2565
                P        +PG   E         K +  + GP     GP D N+ G +G+   P
Sbjct: 927  LQGQP-------GLPGPTGEKGS------KGEPGLPGP----PGPMDPNLLGSKGEKGEP 969

Query: 2566 KLKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGD--LKGPEVDIKGPKVDIN 2623
             L         P +S P     L G       D   P + G   L GP     GPK +  
Sbjct: 970  GLP------GIPGVSGPKGYQGLPG-------DPGQPGLSGQPGLPGP----PGPKGNPG 1012

Query: 2624 AP-DVGVQGPDWHLKMPKVK--MPKFSMPGFKG-EGPDGDVKLP--KADIDVSGPKVDIE 2677
             P   G+ GP      P +K  +     PG +G EGP G   +P       + G K D  
Sbjct: 1013 LPGQPGLIGP------PGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKG 1066

Query: 2678 GPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDV-DVSLPKVEG-- 2734
             P ++  G  G L GPK               P +      P +KG V D  LP + G  
Sbjct: 1067 DPGISSIGLPG-LPGPK-------------GEPGLPGYPGNPGIKGSVGDPGLPGLPGTP 1112

Query: 2735 DLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKIKMPKISMPGFKGE-GPDVDVNLPKA 2793
              KG       P          + GP  +  +P    P +   G  G+ GP  +   P  
Sbjct: 1113 GAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGP-VGGGGHPGQPGPPGEKGKPGQ 1171

Query: 2794 DIDVSGPKVDVECPDVNIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDV 2853
            D  + GP            G +G+   P F  P      P +S    D  L  P I G+ 
Sbjct: 1172 D-GIPGP-----------AGQKGEPGQPGFGNPGPP-GLPGLSGQKGDGGL--PGIPGNP 1216

Query: 2854 DVTGPKVEGDLKG-PEVDLKGPKVDIDVPDVNVQGPDWHLKMPKMKMPKFSMPGFKAEGP 2912
             + GPK E    G P V  +GP      P   ++GP  +   P  + P    PG    GP
Sbjct: 1217 GLPGPKGEPGFHGFPGV--QGPPGPPGSPGPALEGPKGN---PGPQGPP-GRPGL--PGP 1268

Query: 2913 EVDVNLPKADVDVSGPKVDVEGPDV-------NIEGPEGKLKGPKFKMPEMNIKA-PKIP 2964
            E    LP  +  + G K +   P +         +GP G L+G   +     +K  P +P
Sbjct: 1269 EGPPGLP-GNGGIKGEKGNPGQPGLPGLPGLKGDQGPPG-LQGNPGRPGLNGMKGDPGLP 1326

Query: 2965 -MPDFDLHLKGPKVKGDVDISLPKVEGDLKGP--EVDIRGPQ-----VDIDVPDVGVQGP 3016
             +P F   +KGP   G    + P+ E  L GP     + GP      +  D    G+ G 
Sbjct: 1327 GVPGFP-GMKGP--SGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQ 1383

Query: 3017 DWHLKMPKVKMPKFSMPGFKGEGPDVDVN-LPKADLDVSGPKVDIDVPDV----NIEGPE 3071
                 +P  + P+  +PG  G   D   N LP  D    G K D  +P       ++GP 
Sbjct: 1384 PGLKGLPGPQGPQ-GLPGPTGPPGDPGRNGLPGFD-GAGGRKGDPGLPGQPGTRGLDGPP 1441

Query: 3072 GK--LKGP 3077
            G   L+GP
Sbjct: 1442 GPDGLQGP 1449



 Score = 38.1 bits (87), Expect = 0.26
 Identities = 254/1033 (24%), Positives = 358/1033 (34%), Gaps = 243/1033 (23%)

Query: 2939 IEGPEGKLKGPKFKMPEMNIKAPKIPMPDFDLHLKGPKVKGDVDISLPKVEGDLKGPEVD 2998
            ++GP G    P  K    +I    +P P  +    GP          P ++G L GP   
Sbjct: 142  LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGP----------PGIQG-LPGP-TG 189

Query: 2999 IRGPQVDIDVPDV-GVQGPDWHLKMPKVKMP-KFSMP-GFKGE-------GPDVDVNLPK 3048
            I GP      P + G  GP   L  PK  M   F  P G KGE       GP   ++  K
Sbjct: 190  IPGPIGPPGPPGLMGPPGPPG-LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQK 248

Query: 3049 ADLDVSGPKVDIDVPD-------VNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLK 3101
              +DV   K D  +P          I GP G   G K +  E   +  K   P  D    
Sbjct: 249  RPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQG-EPGKRGKPGKDGENG 307

Query: 3102 GPKVKGDMDVSLPKVEGDMKVPDVD-IKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISM 3160
             P + G     LP   G    P  D  KG K D   P     GP      P + +P+   
Sbjct: 308  QPGIPG-----LPGDPGYPGEPGRDGEKGQKGDTGPP-----GP------PGLVIPRPGT 351

Query: 3161 PGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKIS 3220
                GE  + ++ LP     + G K +   P   I+GP   L GP    P   +  P   
Sbjct: 352  GITIGE--KGNIGLP----GLPGEKGERGFP--GIQGPPG-LPGP----PGAAVMGPP-- 396

Query: 3221 MPDLDLNLKGPKMKGEVDVSLANVEGDLKGPALDIKGPK-IDVDAPDIDIHGPDAKLKGP 3279
                      P   GE        +GD   P + I GP  +D       + GP     GP
Sbjct: 397  --------GPPGFPGE-----RGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPA-GP 442

Query: 3280 KLKMPDMHVNMPKISMPEIDLNLKGSKLKGDVDVSGPKLEGDIKAPSLDIKGPEVDVSGP 3339
             +  P   +  P    P      KG  L+G+  V G K +         I GP      P
Sbjct: 443  HIP-PSDEICEPGPPGPPGSPGDKG--LQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLP 499

Query: 3340 KLNIEGKSKKSRFKLPKFNFSGSKVQTPEVDVKGKKPDIDITGPKVDINAPDVEVQGKVK 3399
             L     S           F G K         G+K     TGPK     P         
Sbjct: 500  GLPGPPGS---------LGFPGQK---------GEKGQAGATGPKGLPGIPGAPGAPGFP 541

Query: 3400 GSKFKMPFLSISSPKVSMPDVELNLKSPKVKGDLDIAGPNLEGDFKGPKVDIKAPEVNLN 3459
            GSK +                          GD+ +  P ++GD    K ++ +P     
Sbjct: 542  GSKGE-------------------------PGDI-LTFPGMKGD----KGELGSP----G 567

Query: 3460 APDVD-VHGPDWNLKMPKMKMPKFSVSGL--KAE-GPDVAVDLP--KGDINIEGP-SMNI 3512
            AP +  + G      +P +  PK    G+  K E GP     LP   G+I   GP     
Sbjct: 568  APGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGP 627

Query: 3513 EGP--DLNVEGPEG-----GLKGPKFKMPDMNIKAP-KISMP-----DIDLNLKG-PKVK 3558
             GP  +  ++G  G     G+ GPK   P   I  P K  +P     D D+ L G P + 
Sbjct: 628  PGPVGEKGIQGVAGNPGQPGIPGPKGD-PGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP 686

Query: 3559 GDVDI-SLPKLEGDLKGPEVDIKGPKVDINAPDVD-------------VHGPDWHLKMPK 3604
            G   +  +P  +G+   P + + GP      P +              + GP      P 
Sbjct: 687  GQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG 746

Query: 3605 VK-MPKFSMPG---------FKGE-GPEVDVTLP-------KADID-ISGPNVDVDVPDV 3645
             K  P F++PG         FKG  GP+ D   P       +  +D + GP  DV     
Sbjct: 747  PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV----- 801

Query: 3646 NIEGPDAKLKGPKFK--MPEMNIKAPKISMPDFDLNLKGPKMKGDVVVSLPKVEGDLKGP 3703
               GP+ +  GP     +P + ++ P    P     +  P + G     +P  +GD   P
Sbjct: 802  ---GPNGQ-PGPMGPPGLPGIGVQGPP-GPPGIPGPIGQPGLHG-----IPGEKGDPGPP 851

Query: 3704 EVDIKGPKVDIDTPDI----------NIEGSEGK-----FKGPKFKIPEMHLKAP----- 3743
             +D+ GP  +  +P I             G  GK     F G K ++  M    P     
Sbjct: 852  GLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLG 911

Query: 3744 ---KISMPDI--DLNLKG-PKVKGDVDVSLPKMEGDLKGPE-------VDIKGPKVDINA 3790
               +  +P +  D  L+G P + G       K E  L GP        +  KG K +   
Sbjct: 912  IPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGL 971

Query: 3791 PDV-DVQGPDWHLKMP-KVKMPKFS-MPGFKG-EGPDVDVNLPKADLDVSGPKVDIDVPD 3846
            P +  V GP  +  +P     P  S  PG  G  GP  +  LP     +  P +   + D
Sbjct: 972  PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGD 1031

Query: 3847 VNIEGPEGKLKGP 3859
            +   GP+G ++GP
Sbjct: 1032 MGFPGPQG-VEGP 1043



 Score = 37.0 bits (84), Expect = 0.58
 Identities = 202/844 (23%), Positives = 288/844 (34%), Gaps = 216/844 (25%)

Query: 3760 KGDVDV-SLPKMEGDLKGPEVDIKGPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFK 3818
            KG++ +  LP  +G+   P   I+GP      P   V GP                PGF 
Sbjct: 358  KGNIGLPGLPGEKGERGFP--GIQGPPGLPGPPGAAVMGPP-------------GPPGFP 402

Query: 3819 GEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDI 3878
            GE                G K D   P ++I GP G    P          AP +  P  
Sbjct: 403  GE---------------RGQKGDEGPPGISIPGPPGLDGQPG---------APGLPGPP- 437

Query: 3879 DLNLKGPKVKGDMDVSLPKVEGDMQVP-------DLDIKGPKVD--INAPDVDVRGPDWH 3929
                 GP +    ++  P   G    P       +  +KG K D   N     + GP   
Sbjct: 438  --GPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495

Query: 3930 LKMPKIKMP--KISMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGP 3987
              +P +  P   +  PG KGE         K     +GPK    +P      P A     
Sbjct: 496  PGLPGLPGPPGSLGFPGQKGE---------KGQAGATGPKGLPGIPGA----PGA----- 537

Query: 3988 KFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKVDIDAP 4047
                            P F      P   GD+ ++ P M+GD        KG      AP
Sbjct: 538  ----------------PGFPGSKGEP---GDI-LTFPGMKGD--------KGELGSPGAP 569

Query: 4048 DVD-VHGPDWHLKMPKVKMPKFSMPG--FKGE-GPEVDVNLP--KADIDVSGPKVDIDTP 4101
             +  + G      +P +  PK    G  FKGE GP  +  LP    +I   GP      P
Sbjct: 570  GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGP------P 623

Query: 4102 DIDIHGPEGK--------------LKGPKFKMPDLHLKAPKISMP-----EVDLNLKG-P 4141
                 GP G+              + GPK        +  K  +P     + D+ L G P
Sbjct: 624  GFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDP 683

Query: 4142 KMKGDVDV-SLPKVEGDLKGPEVDIKGPKVDIDVPDVD-------------VQGPDWHLK 4187
             + G   +  +P  +G+   P + + GP      P +              ++GP     
Sbjct: 684  GLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPG 743

Query: 4188 MPKVK-MPKFSMPG---------FKGE-GPDVDVNLP-------KADLD-VSGPKVDIDV 4228
             P  K  P F++PG         FKG  GP  D   P       +  LD + GPK D+  
Sbjct: 744  FPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV-- 801

Query: 4229 PDVNIEGPDAKLKGPKFK--MPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDL 4286
                  GP+ +  GP     +P + ++ P    P     +  P + G     +P  +GD 
Sbjct: 802  ------GPNGQ-PGPMGPPGLPGIGVQGPP-GPPGIPGPIGQPGLHG-----IPGEKGDP 848

Query: 4287 KGPEVDIKGPKVDIDAPDV----DVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVTLPK 4342
              P +D+ GP  +  +P +       GP     +P  K      PG KGE   +    P 
Sbjct: 849  GPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPG-KAGASGFPGTKGEMGMMGPPGPP 907

Query: 4343 ADIEISGPK-VDIDAPDVSIEGPDAKLKGP---KFKMPEMNIKAPKISMPDIDFNLKGPK 4398
              + I G   V     D  ++G    L GP   K    E  +  P   M   D NL G K
Sbjct: 908  GPLGIPGRSGVPGLKGDDGLQGQPG-LPGPTGEKGSKGEPGLPGPPGPM---DPNLLGSK 963

Query: 4399 -VKGDVDVSLPKVEGDLKGPEIDIKGPSLDIDTPDVN----IEGPEGKLKGPKFKMPEMN 4453
              KG  +  LP + G + GP+   +G   D   P ++    + GP G    P        
Sbjct: 964  GEKG--EPGLPGIPG-VSGPK-GYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGL 1019

Query: 4454 IKAPKISMPDFDLHLKGPK-VKGDVDVS----------LPKVESDLKGPEVDIEGPEGKL 4502
            I  P +     D+   GP+ V+G    S          LP  + D   P +   G  G L
Sbjct: 1020 IGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPG-L 1078

Query: 4503 KGPK 4506
             GPK
Sbjct: 1079 PGPK 1082


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score = 79.3 bits (194), Expect = 1e-13
 Identities = 179/638 (28%), Positives = 231/638 (36%), Gaps = 104/638 (16%)

Query: 5160 KGPKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPSVGLEG 5219
            KG K QA    P   + G+      P F  S  +    D+   L  P +KGD   +G  G
Sbjct: 514  KGEKGQAGATGPK-GLPGIPGAPGAPGFPGSKGEPG--DI---LTFPGMKGDKGELGSPG 567

Query: 5220 PD--VDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQ--------LPSLEGDLRGP 5269
                  L G   +   P       G+PG K E GG     +        LP L G++   
Sbjct: 568  APGLPGLPGTPGQDGLP-------GLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPM 620

Query: 5270 DVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGL 5329
                 GP   +   G+   + N   P + GP  D    G ++       +P        +
Sbjct: 621  GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGD---PGQTITQPGKPGLPGNPGRDGDV 677

Query: 5330 NLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGA 5389
             L G  G     G    +PGI  + K   G P + L GP   G     G I  P  + G 
Sbjct: 678  GLPGDPGLPGQPG----LPGIPGS-KGEPGIPGIGLPGPP--GPKGFPG-IPGPPGAPGT 729

Query: 5390 PD-LSLEASEGSIKLPKMK-LPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRI 5447
            P  + LE   G    P  K  P F +  P     +    P   G L GP  D    GP  
Sbjct: 730  PGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGL----PGFKGAL-GPKGDRGFPGP-- 782

Query: 5448 SAPNVDFNLEG-PKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMP---------GI 5497
              P     L+G P  KG +G  G+  GP    GLPGIGVQG  G   +P         GI
Sbjct: 783  PGPPGRTGLDGLPGPKGDVGPNGQ-PGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGI 841

Query: 5498 KSSGCDVNLPGVNVKLPTGQISGPEIKG-----------GL--KGSEVGFHGAAPDISVK 5544
                 D   PG++V  P G+   P I G           GL  K    GF G   ++ + 
Sbjct: 842  PGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMM 901

Query: 5545 GPAFNMASPESDFGINLKG--PKIKGGADVSGGVSAPDISLGEGHLSVKGSGGE-----W 5597
            GP      P    GI  +   P +KG   + G    P      G    KGS GE      
Sbjct: 902  GP----PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLP------GPTGEKGSKGEPGLPGP 951

Query: 5598 KGPQVSSALNLDTSKFAGGL----HFSGPKVEGGVKG--GQIGLQA-PGL-SVSGPQGH- 5648
             GP   + L     K   GL      SGPK   G+ G  GQ GL   PGL    GP+G+ 
Sbjct: 952  PGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNP 1011

Query: 5649 -LESGSGKVTFPKMK--IPKFTFSGRELVGREMGVDVHFPKAEASIQAGAGDGEWEESEV 5705
             L    G +  P +K  I    F G + V    G     P    S       G+  +  +
Sbjct: 1012 GLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPS-GVPGQPGSPGLPGQKGDKGDPGI 1070

Query: 5706 KLKKSKIKMPKFNFSKPKGKGGVTGSP-EASISGSKGD 5742
                S I +P      PKG+ G+ G P    I GS GD
Sbjct: 1071 ----SSIGLP--GLPGPKGEPGLPGYPGNPGIKGSVGD 1102



 Score = 67.4 bits (163), Expect = 4e-10
 Identities = 229/922 (24%), Positives = 316/922 (34%), Gaps = 190/922 (20%)

Query: 4663 PGFKGE-GPDVDVNLPKAD--------IDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPE 4713
            PG  G  G D DV LP             + G K +  +P + + GP     GPK     
Sbjct: 665  PGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPP----GPK----- 715

Query: 4714 MSIKAPKISMPDIDLNLKGPKVKGDVDVTLPKVEGDLKGPEADIKGPKVDINTPDVDVHG 4773
                      P I      P   G + +  P       GP+ +          P   + G
Sbjct: 716  --------GFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGE----------PGFALPG 757

Query: 4774 PDWHLKMPKVKMPKFSMPGFKGE-GPDVDVSLP-------KADID-VSGPKVDVDIPDVN 4824
            P               +PGFKG  GP  D   P       +  +D + GPK DV      
Sbjct: 758  PPGPP----------GLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV------ 801

Query: 4825 IEGPDAKLKGPKFK--MPEINIKAPKISIPDVDLDLKGPKVKGDFDVSVPKVEGTLKGPE 4882
              GP+ +  GP     +P I ++ P             P + G   +  P + G + G +
Sbjct: 802  --GPNGQ-PGPMGPPGLPGIGVQGPP----------GPPGIPGP--IGQPGLHG-IPGEK 845

Query: 4883 VDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLHLKAPKIGFSGPKLEGGEV 4942
             D   P LD  GP  +   P +      I  P        L  KA   GF G K   GE+
Sbjct: 846  GDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG----LPGKAGASGFPGTK---GEM 898

Query: 4943 DLKGPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKFGFGAKSPKADIKSPSLDVTVPE 5002
             + GP      L +   S    ++G D    +   P    G    K     P L      
Sbjct: 899  GMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLP----GPTGEKGSKGEPGLPGPPGP 954

Query: 5003 AELNLETPEISVGGKGKKSKFKMPKIH-MSGPKIKAKKQGFDLNVPGGEIDASLKAPDVD 5061
             + NL      +G KG+K +  +P I  +SGPK      G D   PG      L  P   
Sbjct: 955  MDPNL------LGSKGEKGEPGLPGIPGVSGPKGYQGLPG-DPGQPGLSGQPGLPGPPGP 1007

Query: 5062 VNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEFDIKSPKFKAEAPLP--SPKLEGELQA 5119
                 P    +  +  P   K   G M FP  +  ++ P   +  P    SP L G+   
Sbjct: 1008 KG--NPGLPGQPGLIGPPGLKGTIGDMGFPGPQ-GVEGPPGPSGVPGQPGSPGLPGQKG- 1063

Query: 5120 PDLELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGDLKGPKVQANLGAPDI----NI 5175
               +   P I   GL      P +  P  +  +P   G+   P ++ ++G P +      
Sbjct: 1064 ---DKGDPGISSIGL------PGLPGPKGEPGLPGYPGN---PGIKGSVGDPGLPGLPGT 1111

Query: 5176 EGLDAKVKTPSF----GISAPQ-VSIPDVNVNLKG----------------PKIKGDVPS 5214
             G   +   P F    G   P+ +S P  N  L G                P  KG    
Sbjct: 1112 PGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQ 1171

Query: 5215 VGLEGPDVDLQGPEAKIKFPKFSMP-KIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKL 5273
             G+ GP     G + +   P F  P   G+PG+  + G       LP + G+   P  K 
Sbjct: 1172 DGIPGP----AGQKGEPGQPGFGNPGPPGLPGLSGQKGDGG----LPGIPGNPGLPGPKG 1223

Query: 5274 EGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGLN-LS 5332
            E        PG          P V GP       GP+L+G      P      PG   L 
Sbjct: 1224 E--------PGFH------GFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLP 1269

Query: 5333 GVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRG-PSLQGDLA---VSGDIKCPKVSVG 5388
            G  G   + G+G    GI    K N G P   L G P L+GD     + G+   P ++  
Sbjct: 1270 GPEGPPGLPGNG----GIKGE-KGNPGQPG--LPGLPGLKGDQGPPGLQGNPGRPGLNGM 1322

Query: 5389 APDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRIS 5448
              D  L    G    P MK P      PGS       GP+    L GP     L GP   
Sbjct: 1323 KGDPGLPGVPG---FPGMKGPS---GVPGS------AGPEGEPGLIGPPGPPGLPGPSGQ 1370

Query: 5449 APNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPG-IGVQGLEGNLQMPGIKSSGCDVNLP 5507
            +  +  +   P + G  G  G + GP    GLPG  G  G  G   +PG   +G     P
Sbjct: 1371 SIIIKGDAGPPGIPGQPGLKG-LPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDP 1429

Query: 5508 GVNVKLPTGQISGPEIKGGLKG 5529
            G+  +  T  + GP    GL+G
Sbjct: 1430 GLPGQPGTRGLDGPPGPDGLQG 1451



 Score = 65.1 bits (157), Expect = 2e-09
 Identities = 139/512 (27%), Positives = 179/512 (34%), Gaps = 110/512 (21%)

Query: 5200 NVNLKG-PKIKGDVPSVGLEGPD-------VDLQGPEAKIKFPKFSMPK--IGIPGVKME 5249
            N+ L G P  KG+    G++GP          + GP     FP     K   G PG+ + 
Sbjct: 360  NIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIP 419

Query: 5250 GGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKG- 5308
            G         P L+G    P   L GP     GP +  PS  +  P   GP      KG 
Sbjct: 420  GP--------PGLDGQPGAPG--LPGPP-GPAGPHIP-PSDEICEPGPPGPPGSPGDKGL 467

Query: 5309 ---PSLKGD----------LDASVPSMKVHAPGL-------NLSGVGG-KMQVGGDGVK- 5346
                 +KGD             S P  +   PGL          G  G K Q G  G K 
Sbjct: 468  QGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKG 527

Query: 5347 VPGIDATTKL-----NVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDL-SLEASEGS 5400
            +PGI           + G P   L  P ++GD    G++  P    GAP L  L  + G 
Sbjct: 528  LPGIPGAPGAPGFPGSKGEPGDILTFPGMKGD---KGELGSP----GAPGLPGLPGTPGQ 580

Query: 5401 IKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAP---------- 5450
              LP +  P+     PG       +GP  +  L G   ++   GP    P          
Sbjct: 581  DGLPGLPGPK---GEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQ 637

Query: 5451 NVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGI----------GVQGLEGNLQMPGIKSS 5500
             V  N   P + G  G  G+        GLPG           G  GL G   +PGI  S
Sbjct: 638  GVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGS 697

Query: 5501 GCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGIN 5560
              +  +PG+ +  P G    P I G       G  G    I ++GP      P       
Sbjct: 698  KGEPGIPGIGLPGPPGPKGFPGIPG-----PPGAPGTPGRIGLEGPPGPPGFP------- 745

Query: 5561 LKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFS 5620
              GPK + G  + G    P +   +G L  KG  G    P       LD      GL   
Sbjct: 746  --GPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLD------GL--P 795

Query: 5621 GPKVEGGVKG-----GQIGLQAPGLSVSGPQG 5647
            GPK + G  G     G  GL  PG+ V GP G
Sbjct: 796  GPKGDVGPNGQPGPMGPPGL--PGIGVQGPPG 825



 Score = 59.7 bits (143), Expect = 8e-08
 Identities = 257/1045 (24%), Positives = 345/1045 (33%), Gaps = 195/1045 (18%)

Query: 4664 GFKGEGPDVDVNLPKADIDVSGPKVDVDVPDVNIEGPDAKL--KGPKFKMPEMSIKAPKI 4721
            G KG+  D   N       +SGP     +P   + GP   L   G K +  +     PK 
Sbjct: 472  GVKGDKGDTCFNC--IGTGISGPPGQPGLP--GLPGPPGSLGFPGQKGEKGQAGATGPK- 526

Query: 4722 SMPDIDLNLKGPKVKGDVDVTLPKVEGDLKGPEADI------KGPKVDINTPDVD----V 4771
             +P I      P   G             KG   DI      KG K ++ +P       +
Sbjct: 527  GLPGIPGAPGAPGFPGS------------KGEPGDILTFPGMKGDKGELGSPGAPGLPGL 574

Query: 4772 HGPDWHLKMPKVKMPKFSMPG--FKGE-GPDVDVSLPKADIDVS----------GPKVDV 4818
             G      +P +  PK    G  FKGE GP  +  LP    ++           GP  + 
Sbjct: 575  PGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEK 634

Query: 4819 DIPDVNIEGPDAKLKGPKFKMPEINIKAPKISIP-----DVDLDLKG-PKVKGDFDVSVP 4872
             I  V        + GPK    +   +  K  +P     D D+ L G P + G     +P
Sbjct: 635  GIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQ--PGLP 692

Query: 4873 KVEGTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLHLKAPKIGF 4932
             + G+   P +    P +   GP      P +  P      P              +IG 
Sbjct: 693  GIPGSKGEPGI----PGIGLPGPPGPKGFPGIPGPPGAPGTPG-------------RIGL 735

Query: 4933 SGPKLEGGEVDLKGPKVEAPSLDVHMDSPDINIEGPDVK--IPKFKKPKFGFGAKSPKAD 4990
             GP    G     GPK E          P   + GP     +P FK      GA  PK D
Sbjct: 736  EGPP---GPPGFPGPKGE----------PGFALPGPPGPPGLPGFK------GALGPKGD 776

Query: 4991 IKSPSLDVTVPEAELN-LETPEISVGGKGKKSKFKMPKIHMSGPKIKAKKQGFDLNVPGG 5049
               P          L+ L  P+  VG  G+      P +    P I  +       +PG 
Sbjct: 777  RGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGL----PGIGVQGPPGPPGIPGP 832

Query: 5050 EIDASLKAPDVDVNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEFDIKSPKFKAEAPLP 5109
                 L     +    GP     +DV  P  ++   G    P       SP    +A   
Sbjct: 833  IGQPGLHGIPGEKGDPGPPG---LDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS 889

Query: 5110 S-PKLEGEL-----QAPDLELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGDL--KG 5161
              P  +GE+       P   L +P         ++  P +K  D     P + G    KG
Sbjct: 890  GFPGTKGEMGMMGPPGPPGPLGIPG--------RSGVPGLKGDDGLQGQPGLPGPTGEKG 941

Query: 5162 PKVQANLGAP----DINIEGLDAKVKTPSF----GISAP-----------------QVSI 5196
             K +  L  P    D N+ G   +   P      G+S P                 Q  +
Sbjct: 942  SKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGL 1001

Query: 5197 PDV-----NVNLKG-------PKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIP 5244
            P       N  L G       P +KG +  +G  GP   ++GP      P       G+P
Sbjct: 1002 PGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQ-GVEGPPGPSGVPG-QPGSPGLP 1059

Query: 5245 GVKMEGGGAEVHA-QLPSLEGDLRGPDVKLEGPDVSLKGPGVD--LPSVNLSMPKVSGPD 5301
            G K + G   + +  LP L G    P +     +  +KG   D  LP +  +      P 
Sbjct: 1060 GQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPG 1119

Query: 5302 LDLNLKGPSLKGDLDASVPSMKVHAPGLN--LSGVGGKMQVGGDGVK-VPGID-----AT 5353
            L      P   G    S P      PG    + G G   Q G  G K  PG D     A 
Sbjct: 1120 LPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAG 1179

Query: 5354 TKLNVGAPDVTLRGP-SLQGDLAVSGDIKCPKVSVGAPDLSLEASE-GSIKLPKMKLPQF 5411
             K   G P     GP  L G     GD   P +  G P L     E G    P ++ P  
Sbjct: 1180 QKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIP-GNPGLPGPKGEPGFHGFPGVQGPPG 1238

Query: 5412 GISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPK-VKGSLGATGE 5470
               +PG  L      P   G    PG    L GP           EGP  + G+ G  GE
Sbjct: 1239 PPGSPGPALEGPKGNPGPQGPPGRPGFQ-GLPGP-----------EGPPGLPGNGGIKGE 1286

Query: 5471 IKGPTVGG--GLPGI----GVQGLEGNLQMPGIKSSGCDVNLPGV----NVKLPTG--QI 5518
               P   G  GLPG+    G  GL+GN   PG+     D  LPGV     +K P+G    
Sbjct: 1287 KGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGS 1346

Query: 5519 SGPEIKGGLKG--SEVGFHG-AAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGG 5575
            +GPE + GL G     G  G +   I +KG A     P       L GP  +G   + G 
Sbjct: 1347 AGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGP--QGPQGLPGP 1404

Query: 5576 VSAPDISLGEGHLSVKGSGGEWKGP 5600
               P      G     G+GG    P
Sbjct: 1405 TGPPGDPGRNGLPGFDGAGGRKGDP 1429



 Score = 55.5 bits (132), Expect = 2e-06
 Identities = 142/508 (27%), Positives = 191/508 (37%), Gaps = 81/508 (15%)

Query: 209  PSGSGAASPTGSAVDIRAGAISASGPELQGA-GHSKLQVTMPGIKVGGSGVNVNAKGLDL 267
            P G G   P G    I+  A +   P + G  G     +T PG K G  G N    G D+
Sbjct: 622  PPGFGPPGPVGEK-GIQGVAGNPGQPGIPGPKGDPGQTITQPG-KPGLPG-NPGRDG-DV 677

Query: 268  GGRGGVQVPAVDISSSLGGRAVEVQGPSLE-SGDHGKIKFPTMKVPKFGVSTGREGQTPK 326
            G  G   +P       + G   E   P +   G  G   FP +  P      G  G   +
Sbjct: 678  GLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPP-----GAPGTPGR 732

Query: 327  AGLRVSAPEVSVGHKG--GKPGLTIQAPQLEVSVPSANIEGLEGKLKGPQITGPSLEGDL 384
             GL    P    G  G  G+PG  +  P     +P     G +G L      GP  +GD 
Sbjct: 733  IGLE--GPPGPPGFPGPKGEPGFALPGPPGPPGLP-----GFKGAL------GP--KGDR 777

Query: 385  GLKGAK-PQGHIGVDASAPQIGGSI-----TGPSVEVQAPDIDVQGPGSKLNVPKM--KV 436
            G  G   P G  G+D   P   G +      GP      P I VQGP     +P    + 
Sbjct: 778  GFPGPPGPPGRTGLDG-LPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQP 836

Query: 437  PKFSVSGAKGEE--TGIDVTLPTGE---VTVPGVSGDVSLPEIATGGLEGK-----MKGT 486
                + G KG+    G+DV  P GE     +PG  G +  P   + GL GK       GT
Sbjct: 837  GLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPP--GSPGLPGKAGASGFPGT 894

Query: 487  KVKTPEMIIQKPKISMQDVDLSLGSPKLKGDIKVSAPGVQGD--VKGPQVALKGSRVDIE 544
            K +   M    P   +  +    G P LKGD      G+QG   + GP    KGS+ +  
Sbjct: 895  KGEMGMMGPPGPPGPL-GIPGRSGVPGLKGD-----DGLQGQPGLPGP-TGEKGSKGEPG 947

Query: 545  TPNLEGTLTGPRLGS--PSGKTGTCRISMSEVDLNVAAPKVKGGV--DVTLPRVEGKVKV 600
             P   G +    LGS    G+ G   I        V+ PK   G+  D   P + G+  +
Sbjct: 948  LPGPPGPMDPNLLGSKGEKGEPGLPGIP------GVSGPKGYQGLPGDPGQPGLSGQPGL 1001

Query: 601  PEVDVRGPKVDVSAPDVEAHGPEWNLKMPKMK--MPTFSTPGAKG-EGPDVHMTLP--KG 655
            P     GPK +   P     G    +  P +K  +     PG +G EGP     +P   G
Sbjct: 1002 P--GPPGPKGNPGLP-----GQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPG 1054

Query: 656  DISISGPKVNVEAPDVNLEGLGGKLKGP 683
               + G K +   P ++  GL G L GP
Sbjct: 1055 SPGLPGQKGDKGDPGISSIGLPG-LPGP 1081



 Score = 54.3 bits (129), Expect = 4e-06
 Identities = 224/889 (25%), Positives = 316/889 (35%), Gaps = 167/889 (18%)

Query: 2489 IRGPKVDVNAPDVQAPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDI 2548
            ++GP      P ++     + M  +  PK + PG+   GP     LP     I GP +  
Sbjct: 142  LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGN-PGYP--GPPGIQGLP-GPTGIPGP-IGP 196

Query: 2549 EGPDVNIEGPEGK--LKGPKLKMPEMNIKAPKISMPDFDLHLKGP--------KVKGDVD 2598
             GP   + GP G   L GPK  M  +N + PK    +  L  +GP        + K  +D
Sbjct: 197  PGPP-GLMGPPGPPGLPGPKGNMG-LNFQGPKGEKGEQGL--QGPPGPPGQISEQKRPID 252

Query: 2599 VSLPKVEGDLKG---------------PEVDIKGPKVDINAPDV-GVQGPDWHLKMPKVK 2642
            V   K +  L G               P    KG K +   P   G  G D     P + 
Sbjct: 253  VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312

Query: 2643 -MPKFSMPGFKGE-GPDGDVKLPKADIDVSGPK-VDIEGPDVNIE-GPEGKLKGPKFKMP 2698
             +P    PG+ GE G DG+ K  K D    GP  + I  P   I  G +G +  P     
Sbjct: 313  GLP--GDPGYPGEPGRDGE-KGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE 369

Query: 2699 EMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPK-------VEGDLKGPEVDIKGPK-VDI 2750
            +     P I  P     L GP     +    P         +GD   P + I GP  +D 
Sbjct: 370  KGERGFPGIQGPP---GLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG 426

Query: 2751 DAPDVDVHGPDWHLKMPKIKMPKISMPGFKGE-GPDVDVNLPKADIDVSGPKVDV--ECP 2807
                  + GP            +I  PG  G  G   D  L + +  V G K D    C 
Sbjct: 427  QPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGL-QGEQGVKGDKGDTCFNCI 485

Query: 2808 DVNIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPK-IKGDVDVTGPKVEGDLKG 2866
               I GP G+   P    P      P           TGPK + G     G       KG
Sbjct: 486  GTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKG 545

Query: 2867 PEVDL------KGPKVDIDVPDV----NVQGPDWHLKMPKMKMPKFSMPG--FKAE-GPE 2913
               D+      KG K ++  P       + G      +P +  PK    G  FK E GP 
Sbjct: 546  EPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPP 605

Query: 2914 VDVNLPKADVDVSG---PKVDVEGP--DVNIEGPEGK-----LKGPKFKMPEMNIKAPKI 2963
             +  LP    ++     P     GP  +  I+G  G      + GPK   P   I  P  
Sbjct: 606  GNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGD-PGQTITQPGK 664

Query: 2964 P-MP-----DFDLHLKG-PKVKGDVDI-SLPKVEGDLKGPEVDIRGPQVDIDVPDV---- 3011
            P +P     D D+ L G P + G   +  +P  +G+   P + + GP      P +    
Sbjct: 665  PGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPP 724

Query: 3012 ---------GVQGPDWHLKMPKVK-MPKFSMPG---------FKGE-GPDVDVNLP---- 3047
                     G++GP      P  K  P F++PG         FKG  GP  D   P    
Sbjct: 725  GAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPG 784

Query: 3048 ---KADLD-VSGPKVDIDVPDVNIEGPEGKLKGPKFK--MPEMNIKAPKISMPDIDLNLK 3101
               +  LD + GPK D+        GP G+  GP     +P + ++ P    P I   + 
Sbjct: 785  PPGRTGLDGLPGPKGDV--------GPNGQ-PGPMGPPGLPGIGVQGPP-GPPGIPGPIG 834

Query: 3102 GPKVKGDMDVSLPKVEGDMKVPDVDIKGPKVDINAPDV-DVQGPDWHLKMPKI--KMPKI 3158
             P + G     +P  +GD   P +D+ GP  +  +P +    GP      P +  K    
Sbjct: 835  QPGLHG-----IPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS 889

Query: 3159 SMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPK 3218
              PG KGE   +    P   L + G      VP   ++G D  L+G            P 
Sbjct: 890  GFPGTKGEMGMMGPPGPPGPLGIPGRS---GVP--GLKGDDG-LQG-----------QPG 932

Query: 3219 ISMPDLDLNLKG----PKMKGEVDVSLANVEGDLKGPAL----DIKGPK 3259
            +  P  +   KG    P   G +D +L   +G+   P L     + GPK
Sbjct: 933  LPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPK 981



 Score = 51.2 bits (121), Expect = 3e-05
 Identities = 199/836 (23%), Positives = 285/836 (34%), Gaps = 207/836 (24%)

Query: 2520 MPGFKAEGPEVDVNL---PKADVDISGPK--VDIEGPDVNIEGPEGKLKGPKLKMPE--M 2572
            +PG K E   + ++    PK +    GP     + GP   I GP G    P L  P    
Sbjct: 151  IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGP-TGIPGPIGPPGPPGLMGPPGPP 209

Query: 2573 NIKAPKISMPDFDLHLKGPK-VKGDVDVSLPKVE----GDLKGPEVDIKGPKVDINAP-D 2626
             +  PK +M    L+ +GPK  KG+  +  P        + K P +D++  K D   P D
Sbjct: 210  GLPGPKGNM---GLNFQGPKGEKGEQGLQGPPGPPGQISEQKRP-IDVEFQKGDQGLPGD 265

Query: 2627 VGVQGPDWHLKMPKVKMPKFSMPGFKGE----GPDGDVKLPKADIDVSGPKVDIEGPDVN 2682
             G  GP      P ++ P     G KGE    G  G    P  D +   P +     D  
Sbjct: 266  RGPPGP------PGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPG 319

Query: 2683 IEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKV----KGDVDV-SLPKVEGDLK 2737
              G  G+  G K +  +     P    P + +   G  +    KG++ +  LP  +G+  
Sbjct: 320  YPGEPGR-DGEKGQKGDTGPPGP----PGLVIPRPGTGITIGEKGNIGLPGLPGEKGERG 374

Query: 2738 GPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKADIDV 2797
             P   I+GP      P   V GP                PGF GE               
Sbjct: 375  FP--GIQGPPGLPGPPGAAVMGPP-------------GPPGFPGE--------------- 404

Query: 2798 SGPKVDVECPDVNIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTG 2857
             G K D   P ++I GP G    P           P +  P       GP I    ++  
Sbjct: 405  RGQKGDEGPPGISIPGPPGLDGQPG---------APGLPGPP---GPAGPHIPPSDEICE 452

Query: 2858 PKVEGDLKGP-------EVDLKGPKVD--IDVPDVNVQGPDWHLKMPKMKMPKFSM--PG 2906
            P   G    P       E  +KG K D   +     + GP     +P +  P  S+  PG
Sbjct: 453  PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG 512

Query: 2907 FKAEGPEVDVNLPKADVDVSG-------PKVDVEGPDV----NIEGPEGKLKGPKFK-MP 2954
             K E  +     PK    + G       P    E  D+     ++G +G+L  P    +P
Sbjct: 513  QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572

Query: 2955 EMNIKAPKIPMPDFDLHLKGPKVK-GDVDIS-------------LPKVEGDLKGPEVDIR 3000
             +    P  P  D    L GPK + G +                LP   G +  P     
Sbjct: 573  GL----PGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPP 628

Query: 3001 GPQVDIDVPDVGVQGPDWHLKMPKVKMPK------FSMPGFKG----EGPDVDVNLPKAD 3050
            GP     V + G+QG   +   P +  PK       + PG  G     G D DV LP   
Sbjct: 629  GP-----VGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDP 683

Query: 3051 --------LDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKG 3102
                      + G K +  +P + + GP G    P    P      P        + L+G
Sbjct: 684  GLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPG------RIGLEG 737

Query: 3103 PKVKGDMDVSLPKVEGDMKVPDVDIKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISMPG 3162
            P          P   G    P   + GP            GP               +PG
Sbjct: 738  PP-------GPPGFPGPKGEPGFALPGPP-----------GPP-------------GLPG 766

Query: 3163 FKGE-GPEVDVNLP-------KADLD-VSGPKVDVDVPDVNIEGPDAKLKGPKFK--MPE 3211
            FKG  GP+ D   P       +  LD + GPK DV        GP+ +  GP     +P 
Sbjct: 767  FKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV--------GPNGQ-PGPMGPPGLPG 817

Query: 3212 MNIKAPKISMPDLDLNLKGPKMKGEVDVSLANVEGDLKGPALDIKGPKIDVDAPDI 3267
            + ++ P    P +   +  P + G     +   +GD   P LD+ GP  +  +P I
Sbjct: 818  IGVQGPP-GPPGIPGPIGQPGLHG-----IPGEKGDPGPPGLDVPGPPGERGSPGI 867



 Score = 47.4 bits (111), Expect = 4e-04
 Identities = 168/698 (24%), Positives = 247/698 (35%), Gaps = 144/698 (20%)

Query: 3500 KGDINIEGPSMNIEGPDLNVEGPEGGLKGPKFKMPDMNIKAPKISMPDIDLNLKGPKVKG 3559
            KGD   EGP      P +++ GP G          D    AP +  P       GP +  
Sbjct: 408  KGD---EGP------PGISIPGPPG---------LDGQPGAPGLPGPP---GPAGPHIPP 446

Query: 3560 DVDISLPKLEGDLKGP-------EVDIKGPKVD--INAPDVDVHGPDWHLKMPKVKMPKF 3610
              +I  P   G    P       E  +KG K D   N     + GP     +P +  P  
Sbjct: 447  SDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPG 506

Query: 3611 SM--PGFKGEGPEVDVTLPKADIDISGPNVDVDVPDVNIEGPDAK----LKGPKFKMPEM 3664
            S+  PG KGE  +   T PK    I G       P    E  D      +KG K ++   
Sbjct: 507  SLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSP 566

Query: 3665 NIKA----PKISMPDFDLNLKGPKMKGDVVV-----------SLPKVEGDLKGPEVDIKG 3709
                    P     D    L GPK +   +             LP + G++        G
Sbjct: 567  GAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFG 626

Query: 3710 PKVDIDTPDIN-IEGSEGK--FKGPKFKIPEMHLKAPKISMP-----DIDLNLKG-PKVK 3760
            P   +    I  + G+ G+    GPK    +   +  K  +P     D D+ L G P + 
Sbjct: 627  PPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP 686

Query: 3761 GDVDV-SLPKMEGDLKGPEVDIKGPKVDINAPDVD-------------VQGPDWHLKMPK 3806
            G   +  +P  +G+   P + + GP      P +              ++GP      P 
Sbjct: 687  GQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG 746

Query: 3807 VK-MPKFSMPG---------FKGE-GPDVDVNLP-------KADLD-VSGPKVDIDVPDV 3847
             K  P F++PG         FKG  GP  D   P       +  LD + GPK D+     
Sbjct: 747  PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV----- 801

Query: 3848 NIEGPEGKLKGPKFK--MPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMQVP 3905
               GP G+  GP     +P + ++ P    P I   +  P + G     +P  +GD   P
Sbjct: 802  ---GPNGQ-PGPMGPPGLPGIGVQGPP-GPPGIPGPIGQPGLHG-----IPGEKGDPGPP 851

Query: 3906 DLDIKGPKVDINAPDVDVR----GPDWHLKMPKIKMPKISMPGFKGEGPEVDVNLPKADL 3961
             LD+ GP  +  +P +       GP     +P  K      PG KGE   +    P   L
Sbjct: 852  GLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPG-KAGASGFPGTKGEMGMMGPPGPPGPL 910

Query: 3962 DVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDV 4021
             + G      VP   ++G D  L+G            P +  P  +   KG       + 
Sbjct: 911  GIPGRS---GVP--GLKGDDG-LQG-----------QPGLPGPTGEKGSKG-------EP 946

Query: 4022 SLPKMEGDLKAPEVDIKGPKVDIDAPDV-DVHGPDWHLKMP-KVKMPKFS-MPGFKG-EG 4077
             LP   G +    +  KG K +   P +  V GP  +  +P     P  S  PG  G  G
Sbjct: 947  GLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPG 1006

Query: 4078 PEVDVNLPKADIDVSGPKVDIDTPDIDIHGPEGKLKGP 4115
            P+ +  LP     +  P +     D+   GP+G ++GP
Sbjct: 1007 PKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQG-VEGP 1043



 Score = 47.0 bits (110), Expect = 6e-04
 Identities = 129/480 (26%), Positives = 165/480 (34%), Gaps = 80/480 (16%)

Query: 5242 GIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPD--VSLKGP-GVDLPSVNLSMPKVS 5298
            GIPG+K E G   + + LP  +G+   P     GP     L GP G+  P      P + 
Sbjct: 150  GIPGMKGEPGSI-IMSSLPGPKGNPGYP-----GPPGIQGLPGPTGIPGPIGPPGPPGLM 203

Query: 5299 GPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLSGVGGKMQVGGDGVK----VPGIDATT 5354
            GP     L GP  KG++            GLN  G  G+   G  G++     PG  +  
Sbjct: 204  GPPGPPGLPGP--KGNM------------GLNFQGPKGEK--GEQGLQGPPGPPGQISEQ 247

Query: 5355 KLNVGAP----DVTLRG-------PSLQGDLAVSGDIKCPKVSVGAPDL----SLEASEG 5399
            K  +       D  L G       P ++G     G  K  K   G P        +   G
Sbjct: 248  KRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENG 307

Query: 5400 SIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRIS-APNVDFNLEG 5458
               +P +         PG D     KG   +G    PG+ +   G  I+     +  L G
Sbjct: 308  QPGIPGLPGDPGYPGEPGRDGEKGQKGD--TGPPGPPGLVIPRPGTGITIGEKGNIGLPG 365

Query: 5459 -PKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQ 5517
             P  KG  G  G I+GP    G PG  V G  G    PG +    D   PG+++  P G 
Sbjct: 366  LPGEKGERGFPG-IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGL 424

Query: 5518 ISGPEIKG--GLKGSEVGFHGAAPDISVKGPAFNMASP--------------ESDFGINL 5561
               P   G  G  G        + +I   GP     SP              + D   N 
Sbjct: 425  DGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNC 484

Query: 5562 KGPKIKGGADVSG--GVSAPDISLG-EGHLSVKGSGGEW--KG----PQVSSALNLDTSK 5612
             G  I G     G  G+  P  SLG  G    KG  G    KG    P    A     SK
Sbjct: 485  IGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSK 544

Query: 5613 FAGG--LHFSGPKVEGGVKGGQIGLQAPGLSVSGPQGHLESGSGKVTFPKMKIPKFTFSG 5670
               G  L F G K + G  G       PGL  +  Q  L    G    PK +    TF G
Sbjct: 545  GEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPG----PKGEPGGITFKG 600



 Score = 45.4 bits (106), Expect = 0.002
 Identities = 278/1149 (24%), Positives = 398/1149 (34%), Gaps = 265/1149 (23%)

Query: 2025 IKGPKMD--IDAPDVDVHGPDWHLKMPKMKMPKFSM--PGFKAE-------GPEVDVNLP 2073
            +KG K D   +     + GP     +P +  P  S+  PG K E       GP+    +P
Sbjct: 473  VKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIP 532

Query: 2074 KADVVVSGPKVDVEVPDV----SLEGPEGKLKGPKLK-MPEMHFKAPKISMPDVDLHLKG 2128
             A      P    E  D+     ++G +G+L  P    +P +     +  +P     L G
Sbjct: 533  GAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPG----LPG 588

Query: 2129 PK-------VKGDV----DVSLPKLEGDL----------TGPSVDVEVPDVELECPDAKL 2167
            PK        KG+     +  LP L G++           GP  +  +  V        +
Sbjct: 589  PKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGI 648

Query: 2168 KGPKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMDV-SVPKVEGEMKVPDVDIRGPKVD 2226
             GPK    +   +  K  +P        P   GD+ +   P + G+  +P +   G K +
Sbjct: 649  PGPKGDPGQTITQPGKPGLPG------NPGRDGDVGLPGDPGLPGQPGLPGIP--GSKGE 700

Query: 2227 IDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKGEGPEVDVNLPKADVDVSGPKVDVEVPDV 2286
               P + + GP      P +  P    PG  G    + +  P       GPK +   P  
Sbjct: 701  PGIPGIGLPGPPGPKGFPGIPGP----PGAPGTPGRIGLEGPPGPPGFPGPKGE---PGF 753

Query: 2287 SLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVDVSAPK-------LEG 2339
            +L GP G    P FK                     GPK  GD     P        L+G
Sbjct: 754  ALPGPPGPPGLPGFK------------------GALGPK--GDRGFPGPPGPPGRTGLDG 793

Query: 2340 ELKGPELDV-----KGPKLDADMPEVAVEGPNGKWKTPKFKMPDMHFKAPKISMPDLDLH 2394
             L GP+ DV      GP     +P + V+GP G                P I  P     
Sbjct: 794  -LPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGP---------------PGIPGP----- 832

Query: 2395 LKSPKAKGEVDVDVPKLEGDLKGPHVDVSGPDIDIEGPEGKLKGPKFKMPDMHFKAPNIS 2454
                       +  P L G + G   D   P +D+ GP G+   P          AP   
Sbjct: 833  -----------IGQPGLHG-IPGEKGDPGPPGLDVPGPPGERGSPGIP------GAPGPI 874

Query: 2455 MPDVDLNLKG-------PKIKGDVD-VSVPEVEGKLEVPDMNIRGPKVDVNAPDVQAPDW 2506
             P     L G       P  KG++  +  P   G L +P  +          P ++  D 
Sbjct: 875  GPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRS--------GVPGLKGDDG 926

Query: 2507 HLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDIEGP-DVNIEGPEGKLKGP 2565
                P        +PG   E         K +  + GP     GP D N+ G +G+   P
Sbjct: 927  LQGQP-------GLPGPTGEKGS------KGEPGLPGP----PGPMDPNLLGSKGEKGEP 969

Query: 2566 KLKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGD--LKGPEVDIKGPKVDIN 2623
             L         P +S P     L G       D   P + G   L GP     GPK +  
Sbjct: 970  GLP------GIPGVSGPKGYQGLPG-------DPGQPGLSGQPGLPGP----PGPKGNPG 1012

Query: 2624 AP-DVGVQGPDWHLKMPKVK--MPKFSMPGFKG-EGPDGDVKLP--KADIDVSGPKVDIE 2677
             P   G+ GP      P +K  +     PG +G EGP G   +P       + G K D  
Sbjct: 1013 LPGQPGLIGP------PGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKG 1066

Query: 2678 GPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDV-DVSLPKVEG-- 2734
             P ++  G  G L GPK               P +      P +KG V D  LP + G  
Sbjct: 1067 DPGISSIGLPG-LPGPK-------------GEPGLPGYPGNPGIKGSVGDPGLPGLPGTP 1112

Query: 2735 DLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKIKMPKISMPGFKGE-GPDVDVNLPKA 2793
              KG       P          + GP  +  +P    P +   G  G+ GP  +   P  
Sbjct: 1113 GAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGP-VGGGGHPGQPGPPGEKGKPGQ 1171

Query: 2794 DIDVSGPKVDVECPDVNIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDV 2853
            D  + GP            G +G+   P F  P      P +S    D  L  P I G+ 
Sbjct: 1172 D-GIPGP-----------AGQKGEPGQPGFGNPGPP-GLPGLSGQKGDGGL--PGIPGNP 1216

Query: 2854 DVTGPKVEGDLKG-PEVDLKGPKVDIDVPDVNVQGPDWHLKMPKMKMPKFSMPGFKA-EG 2911
             + GPK E    G P V  +GP      P   ++GP  +   P  + P    PGF+   G
Sbjct: 1217 GLPGPKGEPGFHGFPGV--QGPPGPPGSPGPALEGPKGN---PGPQGPP-GRPGFQGLPG 1270

Query: 2912 PEVDVNLPKADVDVSGPKVDVEGPDV-------NIEGPEGKLKGPKFKMPEMNIKA-PKI 2963
            PE    LP  +  + G K +   P +         +GP G L+G   +     +K  P +
Sbjct: 1271 PEGPPGLP-GNGGIKGEKGNPGQPGLPGLPGLKGDQGPPG-LQGNPGRPGLNGMKGDPGL 1328

Query: 2964 P-MPDFDLHLKGPKVKGDVDISLPKVEGDLKGP--EVDIRGPQ-----VDIDVPDVGVQG 3015
            P +P F   +KGP   G    + P+ E  L GP     + GP      +  D    G+ G
Sbjct: 1329 PGVPGFP-GMKGP--SGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPG 1385

Query: 3016 PDWHLKMPKVKMPKFSMPGFKGEGPDVDVN-LPKADLDVSGPKVDIDVPDV----NIEGP 3070
                  +P  + P+  +PG  G   D   N LP  D    G K D  +P       ++GP
Sbjct: 1386 QPGLKGLPGPQGPQ-GLPGPTGPPGDPGRNGLPGFD-GAGGRKGDPGLPGQPGTRGLDGP 1443

Query: 3071 EGK--LKGP 3077
             G   L+GP
Sbjct: 1444 PGPDGLQGP 1452



 Score = 42.4 bits (98), Expect = 0.014
 Identities = 164/684 (23%), Positives = 233/684 (34%), Gaps = 149/684 (21%)

Query: 291  VQGPSLESGDHGKIKFPTMKVPKFGVSTGREGQTPKAGLR-VSAPEVSVGHKG-----GK 344
            +QG     GD G   F         + TG  G   + GL  +  P  S+G  G     G+
Sbjct: 467  LQGEQGVKGDKGDTCFNC-------IGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQ 519

Query: 345  PGLTIQAPQLEVSVPSA----NIEGLEGKLKGPQITGPSLEGDLGLKGAK-PQGHIGVDA 399
             G T   P+    +P A       G +G+  G  +T P ++GD G  G+    G  G+  
Sbjct: 520  AGAT--GPKGLPGIPGAPGAPGFPGSKGE-PGDILTFPGMKGDKGELGSPGAPGLPGLPG 576

Query: 400  SAPQIG-GSITGPSVEV--------QAPDIDVQGPGSKLNVPKMKVPKFSVSGAKGEETG 450
            +  Q G   + GP  E         + P  +   PG   N+  M  P F   G  GE+  
Sbjct: 577  TPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGI 636

Query: 451  IDVTLPTGEVTVPGVSGD--VSLPEIATGGLEGKMKGTKVKTPEMIIQKPKISMQDVDLS 508
              V    G+  +PG  GD   ++ +    GL G                     +D D+ 
Sbjct: 637  QGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGN------------------PGRDGDVG 678

Query: 509  L-GSPKLKGDIKVSAPGVQGDVKGPQVALKGSRVDIETPNLEGTLTGPRLGSPSGKTGT- 566
            L G P L G  +   PG+ G    P +        I  P   G    P +  P G  GT 
Sbjct: 679  LPGDPGLPG--QPGLPGIPGSKGEPGIP------GIGLPGPPGPKGFPGIPGPPGAPGTP 730

Query: 567  CRISMSEVDLNVAAPKVKGGVDVTLPRVEGKVKVPEV-DVRGPKVDVSAPDVEAHGPEWN 625
             RI +         P  KG     LP   G   +P      GPK D   P     GP   
Sbjct: 731  GRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFP-----GP--- 782

Query: 626  LKMPKMKMPTFSTPGAKGEGPDVHMTLPKGDISISGPKVNVEAPDVNLEGLGGKLKGPDV 685
                         PG  G      +  PKGD+  +G    +  P   L G+G  ++GP  
Sbjct: 783  -------------PGPPGRTGLDGLPGPKGDVGPNGQPGPMGPP--GLPGIG--VQGPP- 824

Query: 686  KLPDMSVKTPKISMPDVDLHVKGTKVKGEYDVTVPKLEGELKGPKVDIDAPDVDVHGPDW 745
                     P I  P                +  P L G + G K D   P +DV GP  
Sbjct: 825  -------GPPGIPGP----------------IGQPGLHG-IPGEKGDPGPPGLDVPGPPG 860

Query: 746  HLKMPKMKMPKFSVPGFKAE-GPEVDVNLP-----------KADVDISGPKIDVTAPDVS 793
                P        +PG     GP     LP           K ++ + GP      P   
Sbjct: 861  ERGSP-------GIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP----PGPPGP 909

Query: 794  IEEPEGKLKGPKFKMPEMNIKVPKISMPDVDLHLKG-PNVKGEYDVTMPKVESEIKVPDV 852
            +  P G+   P  K  +     P +  P  +   KG P + G      P +        +
Sbjct: 910  LGIP-GRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNL--------L 960

Query: 853  ELKSAKMDIDVPDVE-VQGPDWHLKMP-KMKMPKFS-MPGFKA-EGPEVDVNLPKADVDI 908
              K  K +  +P +  V GP  +  +P     P  S  PG     GP+ +  LP     I
Sbjct: 961  GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI 1020

Query: 909  SGPKVGVEVPDVNIEGPEGKLKGP 932
              P +   + D+   GP+G ++GP
Sbjct: 1021 GPPGLKGTIGDMGFPGPQG-VEGP 1043



 Score = 38.1 bits (87), Expect = 0.26
 Identities = 254/1033 (24%), Positives = 358/1033 (34%), Gaps = 243/1033 (23%)

Query: 2939 IEGPEGKLKGPKFKMPEMNIKAPKIPMPDFDLHLKGPKVKGDVDISLPKVEGDLKGPEVD 2998
            ++GP G    P  K    +I    +P P  +    GP          P ++G L GP   
Sbjct: 142  LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGP----------PGIQG-LPGP-TG 189

Query: 2999 IRGPQVDIDVPDV-GVQGPDWHLKMPKVKMP-KFSMP-GFKGE-------GPDVDVNLPK 3048
            I GP      P + G  GP   L  PK  M   F  P G KGE       GP   ++  K
Sbjct: 190  IPGPIGPPGPPGLMGPPGPPG-LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQK 248

Query: 3049 ADLDVSGPKVDIDVPD-------VNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLK 3101
              +DV   K D  +P          I GP G   G K +  E   +  K   P  D    
Sbjct: 249  RPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQG-EPGKRGKPGKDGENG 307

Query: 3102 GPKVKGDMDVSLPKVEGDMKVPDVD-IKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISM 3160
             P + G     LP   G    P  D  KG K D   P     GP      P + +P+   
Sbjct: 308  QPGIPG-----LPGDPGYPGEPGRDGEKGQKGDTGPP-----GP------PGLVIPRPGT 351

Query: 3161 PGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKIS 3220
                GE  + ++ LP     + G K +   P   I+GP   L GP    P   +  P   
Sbjct: 352  GITIGE--KGNIGLP----GLPGEKGERGFP--GIQGPPG-LPGP----PGAAVMGPP-- 396

Query: 3221 MPDLDLNLKGPKMKGEVDVSLANVEGDLKGPALDIKGPK-IDVDAPDIDIHGPDAKLKGP 3279
                      P   GE        +GD   P + I GP  +D       + GP     GP
Sbjct: 397  --------GPPGFPGE-----RGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPA-GP 442

Query: 3280 KLKMPDMHVNMPKISMPEIDLNLKGSKLKGDVDVSGPKLEGDIKAPSLDIKGPEVDVSGP 3339
             +  P   +  P    P      KG  L+G+  V G K +         I GP      P
Sbjct: 443  HIP-PSDEICEPGPPGPPGSPGDKG--LQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLP 499

Query: 3340 KLNIEGKSKKSRFKLPKFNFSGSKVQTPEVDVKGKKPDIDITGPKVDINAPDVEVQGKVK 3399
             L     S           F G K         G+K     TGPK     P         
Sbjct: 500  GLPGPPGS---------LGFPGQK---------GEKGQAGATGPKGLPGIPGAPGAPGFP 541

Query: 3400 GSKFKMPFLSISSPKVSMPDVELNLKSPKVKGDLDIAGPNLEGDFKGPKVDIKAPEVNLN 3459
            GSK +                          GD+ +  P ++GD    K ++ +P     
Sbjct: 542  GSKGE-------------------------PGDI-LTFPGMKGD----KGELGSP----G 567

Query: 3460 APDVD-VHGPDWNLKMPKMKMPKFSVSGL--KAE-GPDVAVDLP--KGDINIEGP-SMNI 3512
            AP +  + G      +P +  PK    G+  K E GP     LP   G+I   GP     
Sbjct: 568  APGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGP 627

Query: 3513 EGP--DLNVEGPEG-----GLKGPKFKMPDMNIKAP-KISMP-----DIDLNLKG-PKVK 3558
             GP  +  ++G  G     G+ GPK   P   I  P K  +P     D D+ L G P + 
Sbjct: 628  PGPVGEKGIQGVAGNPGQPGIPGPKGD-PGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP 686

Query: 3559 GDVDI-SLPKLEGDLKGPEVDIKGPKVDINAPDVD-------------VHGPDWHLKMPK 3604
            G   +  +P  +G+   P + + GP      P +              + GP      P 
Sbjct: 687  GQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG 746

Query: 3605 VK-MPKFSMPG---------FKGE-GPEVDVTLP-------KADID-ISGPNVDVDVPDV 3645
             K  P F++PG         FKG  GP+ D   P       +  +D + GP  DV     
Sbjct: 747  PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV----- 801

Query: 3646 NIEGPDAKLKGPKFK--MPEMNIKAPKISMPDFDLNLKGPKMKGDVVVSLPKVEGDLKGP 3703
               GP+ +  GP     +P + ++ P    P     +  P + G     +P  +GD   P
Sbjct: 802  ---GPNGQ-PGPMGPPGLPGIGVQGPP-GPPGIPGPIGQPGLHG-----IPGEKGDPGPP 851

Query: 3704 EVDIKGPKVDIDTPDI----------NIEGSEGK-----FKGPKFKIPEMHLKAP----- 3743
             +D+ GP  +  +P I             G  GK     F G K ++  M    P     
Sbjct: 852  GLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLG 911

Query: 3744 ---KISMPDI--DLNLKG-PKVKGDVDVSLPKMEGDLKGPE-------VDIKGPKVDINA 3790
               +  +P +  D  L+G P + G       K E  L GP        +  KG K +   
Sbjct: 912  IPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGL 971

Query: 3791 PDV-DVQGPDWHLKMP-KVKMPKFS-MPGFKG-EGPDVDVNLPKADLDVSGPKVDIDVPD 3846
            P +  V GP  +  +P     P  S  PG  G  GP  +  LP     +  P +   + D
Sbjct: 972  PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGD 1031

Query: 3847 VNIEGPEGKLKGP 3859
            +   GP+G ++GP
Sbjct: 1032 MGFPGPQG-VEGP 1043



 Score = 37.0 bits (84), Expect = 0.58
 Identities = 202/844 (23%), Positives = 288/844 (34%), Gaps = 216/844 (25%)

Query: 3760 KGDVDV-SLPKMEGDLKGPEVDIKGPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFK 3818
            KG++ +  LP  +G+   P   I+GP      P   V GP                PGF 
Sbjct: 358  KGNIGLPGLPGEKGERGFP--GIQGPPGLPGPPGAAVMGPP-------------GPPGFP 402

Query: 3819 GEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDI 3878
            GE                G K D   P ++I GP G    P          AP +  P  
Sbjct: 403  GE---------------RGQKGDEGPPGISIPGPPGLDGQPG---------APGLPGPP- 437

Query: 3879 DLNLKGPKVKGDMDVSLPKVEGDMQVP-------DLDIKGPKVD--INAPDVDVRGPDWH 3929
                 GP +    ++  P   G    P       +  +KG K D   N     + GP   
Sbjct: 438  --GPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495

Query: 3930 LKMPKIKMP--KISMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGP 3987
              +P +  P   +  PG KGE         K     +GPK    +P      P A     
Sbjct: 496  PGLPGLPGPPGSLGFPGQKGE---------KGQAGATGPKGLPGIPGA----PGA----- 537

Query: 3988 KFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKVDIDAP 4047
                            P F      P   GD+ ++ P M+GD        KG      AP
Sbjct: 538  ----------------PGFPGSKGEP---GDI-LTFPGMKGD--------KGELGSPGAP 569

Query: 4048 DVD-VHGPDWHLKMPKVKMPKFSMPG--FKGE-GPEVDVNLP--KADIDVSGPKVDIDTP 4101
             +  + G      +P +  PK    G  FKGE GP  +  LP    +I   GP      P
Sbjct: 570  GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGP------P 623

Query: 4102 DIDIHGPEGK--------------LKGPKFKMPDLHLKAPKISMP-----EVDLNLKG-P 4141
                 GP G+              + GPK        +  K  +P     + D+ L G P
Sbjct: 624  GFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDP 683

Query: 4142 KMKGDVDV-SLPKVEGDLKGPEVDIKGPKVDIDVPDVD-------------VQGPDWHLK 4187
             + G   +  +P  +G+   P + + GP      P +              ++GP     
Sbjct: 684  GLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPG 743

Query: 4188 MPKVK-MPKFSMPG---------FKGE-GPDVDVNLP-------KADLD-VSGPKVDIDV 4228
             P  K  P F++PG         FKG  GP  D   P       +  LD + GPK D+  
Sbjct: 744  FPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV-- 801

Query: 4229 PDVNIEGPDAKLKGPKFK--MPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDL 4286
                  GP+ +  GP     +P + ++ P    P     +  P + G     +P  +GD 
Sbjct: 802  ------GPNGQ-PGPMGPPGLPGIGVQGPP-GPPGIPGPIGQPGLHG-----IPGEKGDP 848

Query: 4287 KGPEVDIKGPKVDIDAPDV----DVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVTLPK 4342
              P +D+ GP  +  +P +       GP     +P  K      PG KGE   +    P 
Sbjct: 849  GPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPG-KAGASGFPGTKGEMGMMGPPGPP 907

Query: 4343 ADIEISGPK-VDIDAPDVSIEGPDAKLKGP---KFKMPEMNIKAPKISMPDIDFNLKGPK 4398
              + I G   V     D  ++G    L GP   K    E  +  P   M   D NL G K
Sbjct: 908  GPLGIPGRSGVPGLKGDDGLQGQPG-LPGPTGEKGSKGEPGLPGPPGPM---DPNLLGSK 963

Query: 4399 -VKGDVDVSLPKVEGDLKGPEIDIKGPSLDIDTPDVN----IEGPEGKLKGPKFKMPEMN 4453
              KG  +  LP + G + GP+   +G   D   P ++    + GP G    P        
Sbjct: 964  GEKG--EPGLPGIPG-VSGPK-GYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGL 1019

Query: 4454 IKAPKISMPDFDLHLKGPK-VKGDVDVS----------LPKVESDLKGPEVDIEGPEGKL 4502
            I  P +     D+   GP+ V+G    S          LP  + D   P +   G  G L
Sbjct: 1020 IGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPG-L 1078

Query: 4503 KGPK 4506
             GPK
Sbjct: 1079 PGPK 1082


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score = 72.4 bits (176), Expect = 1e-11
 Identities = 181/707 (25%), Positives = 244/707 (34%), Gaps = 153/707 (21%)

Query: 5103 KAEAPLP----SPKLEGELQAPDLELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGD 5158
            K +A  P    SP L G    P   + LP     G +    +P    P  D   P   G 
Sbjct: 617  KGQAGFPGGPGSPGLPGPKGEPGKIVPLPG--PPGAEGLPGSPGFPGPQGDRGFPGTPGR 674

Query: 5159 LKGPKVQANLGAPDIN---------IEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIK 5209
               P  +  +G P I          ++GL   +  P          +P  N  ++G K +
Sbjct: 675  PGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPG-NPGVQGQKGE 733

Query: 5210 GDVPSVGLEGPDVDLQGPEAKIKFPKFSMPK--IGIPGVKMEGG--------GAEVHAQL 5259
               P VGL G    L+G       P     K  IG+PGV  E G        G       
Sbjct: 734  ---PGVGLPG----LKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGP 786

Query: 5260 PSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASV 5319
            P L G +  P V   GP      PG   P      P +SGP        P +KG+     
Sbjct: 787  PGLPGSVGSPGVPGIGP------PGARGPPGGQGPPGLSGP--------PGIKGE--KGF 830

Query: 5320 PSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKL-----NVGAPDVTLRGPSLQGDL 5374
            P      PGL++ G  G     G    +PGI   + L       GAP +    P  +G++
Sbjct: 831  PGF----PGLDMPGPKGDKGAQG----LPGITGQSGLPGLPGQQGAPGIP-GFPGSKGEM 881

Query: 5375 AVSGDIKCPKVS--VGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGE 5432
             V G    P     VGAP L  E  +                 PGS       GP+    
Sbjct: 882  GVMGTPGQPGSPGPVGAPGLPGEKGDHGF--------------PGSS------GPRGDPG 921

Query: 5433 LKGPGVDVNLKGPRISAPNVDF-NLEGPK----VKGSLGATGEIKGPTVGGGLPGI---- 5483
            LKG   DV L G   S   VD  +++G K     KG +G  GE KG     G PG+    
Sbjct: 922  LKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGE-KGSRGDPGTPGVPGKD 980

Query: 5484 ---------------GVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLK 5528
                           G+ G  G   +PG K S   + LPG   +     I GP+   GL 
Sbjct: 981  GQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLP 1040

Query: 5529 GSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPK-IKGGADVSGGVSAPDISLGEGH 5587
            G +    GA  +    GP           GI + G +  KG   ++G   +P     +G 
Sbjct: 1041 GDK----GAKGEKGQAGPP----------GIGIPGLRGEKGDQGIAGFPGSPGEKGEKGS 1086

Query: 5588 LSVKGSGGE--WKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKG--------GQIGLQA 5637
            + + G  G    KG   S         + G     G K + G+ G        G+ GL  
Sbjct: 1087 IGIPGMPGSPGLKGSPGSVG-------YPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPG 1139

Query: 5638 -PGLSVSGPQGHL-ESGSGKVTFPKMKIPKFTFSGRELVGREMGVDVHFPKAEASIQAGA 5695
             PG   +GP G   E GS  +     +  +    GR   G          K E      A
Sbjct: 1140 TPG--PTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLA 1197

Query: 5696 GDGEWEESEVKLKKSKIKMPKFNFSKPKGKGGVTGSPEASISGSKGD 5742
            G          +  SK +        P+G+ G+ GSP  +  G KGD
Sbjct: 1198 GSPG-------IPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGD 1237



 Score = 63.2 bits (152), Expect = 8e-09
 Identities = 121/489 (24%), Positives = 173/489 (35%), Gaps = 84/489 (17%)

Query: 249  PGIKVGGSGVNVNAKGLDLGGRGGVQVPAVDISSSLGGRAVEVQGPSLESGDHGKIKFPT 308
            PG    G    +  KG   G  GG   P +       G+ V + GP    G  G   FP 
Sbjct: 603  PGPPGYGPAGPIGDKG-QAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPG 661

Query: 309  MKVPKFGVST-------GREGQTPKAGLRVSAPEVSVGHKG-----------GKPGLT-- 348
             +  +    T       G +G   + G+    P    G  G           G+PG    
Sbjct: 662  PQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGL 721

Query: 349  --IQAPQLEVSVPSANIEGLEGKLKGPQITG-PSLEGDLGLKGAK-------PQGHIGV- 397
                  Q +   P   + GL+G    P I G P  +G +G+ G         P G  G+ 
Sbjct: 722  PGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIR 781

Query: 398  -DASAPQIGGSITGPSVEVQAPDIDVQGPGSKLNVPKMKVPKFSVSGAKGEE-----TGI 451
             +   P + GS+  P V    P    +GP      P +  P     G KGE+      G+
Sbjct: 782  GEPGPPGLPGSVGSPGVPGIGPP-GARGPPGGQGPPGLSGPP----GIKGEKGFPGFPGL 836

Query: 452  DVTLPTGEVT---VPGVSGDVSLPEIATGGLEGKMKGTKVKTPEMIIQKPKISMQDVDLS 508
            D+  P G+     +PG++G   LP     GL G+     +  P     K ++ +      
Sbjct: 837  DMPGPKGDKGAQGLPGITGQSGLP-----GLPGQQGAPGI--PGFPGSKGEMGVMGTPGQ 889

Query: 509  LGSPKLKGDIKVSAPGVQGDV--------KGPQ--VALKGSRVDIETPNLEGTLTGPRLG 558
             GSP       V APG+ G+          GP+    LKG + D+  P   G++    +G
Sbjct: 890  PGSPG-----PVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMG 944

Query: 559  SPSGKTGTCRISMSEVDLNVAAPKVKGGVDVTLPRVEGK-VKVPEVDVRGPKVDVSAPDV 617
            S  G+ G       +  +     K   G D   P V GK  +  +    GPK D   P +
Sbjct: 945  SMKGQKGD---QGEKGQIGPIGEKGSRG-DPGTPGVPGKDGQAGQPGQPGPKGD---PGI 997

Query: 618  EAHGPEWNLKMPKMKMPTFSTPGAKGE-------GPDVHMTLPKGDISISGPKVNVEAPD 670
                    L  PK  +     PG  GE       GP     LP GD    G K     P 
Sbjct: 998  SGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLP-GDKGAKGEKGQAGPPG 1056

Query: 671  VNLEGLGGK 679
            + + GL G+
Sbjct: 1057 IGIPGLRGE 1065



 Score = 59.3 bits (142), Expect = 1e-07
 Identities = 142/552 (25%), Positives = 194/552 (35%), Gaps = 115/552 (20%)

Query: 5341 GGDGVK-VPGIDATTKLNVGAP-----------DVTLRG----PSLQGDLAVSGDIKCPK 5384
            G DGV  VPG   T  L +G P           D+ L+G    P   G   ++G    P 
Sbjct: 504  GRDGVAGVPGPQGTPGL-IGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPG 562

Query: 5385 VSVGAPDL-SLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLK 5443
               G P L   + S GS+ L   + P  G+  PGS       GP       GP   +  K
Sbjct: 563  RD-GHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPG----YGPAGPIGDK 617

Query: 5444 GPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGI-------GVQGLEGNLQMPG 5496
            G +   P    +   P  KG  G    + GP    GLPG        G +G  G    PG
Sbjct: 618  G-QAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPG 676

Query: 5497 IKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKG--------SEVGFHGAAPDISVKGPAF 5548
            +      V  PG+    P     GP+   GL G           GF+G   +  V+G   
Sbjct: 677  LPGEKGAVGQPGIGFPGP----PGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQG--- 729

Query: 5549 NMASPESDFGINLKG-------PKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQ 5601
                 + + G+ L G       P I G     G +  P +    G +   G  G    P 
Sbjct: 730  ----QKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEP- 784

Query: 5602 VSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQAPGLSVSGPQGHLESGSGKVTFPKM 5661
                  L  S  + G+   GP    G  GGQ     PGL  SGP G ++   G   FP  
Sbjct: 785  --GPPGLPGSVGSPGVPGIGPPGARGPPGGQ---GPPGL--SGPPG-IKGEKGFPGFP-- 834

Query: 5662 KIPKFTFSGRELVGREMGVDVHFPKAEASIQAGAG-DGEWEESEVKLKKSKIKMPKFNFS 5720
                             G+D+  PK +   Q   G  G+     +  ++    +P F  S
Sbjct: 835  -----------------GLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGS 877

Query: 5721 KPKGKGGVTGSPEASISGSKGDLKSSKASLGSLEGEAEAEASSPKGKFSLFKSKKPRHRS 5780
              KG+ GV G+P     GS G + +       L GE        KG      S  PR   
Sbjct: 878  --KGEMGVMGTP--GQPGSPGPVGAP-----GLPGE--------KGDHGFPGSSGPRGDP 920

Query: 5781 NSFSDEREFSGPSTPTGTLEFEGGEVSLEGGKVKGKHG----KLKFGTFGGLGSK-SKGH 5835
                D+ +   P  P       G    ++ G +KG+ G    K + G  G  GS+   G 
Sbjct: 921  GLKGDKGDVGLPGKP-------GSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGT 973

Query: 5836 YEVTGSDDETGK 5847
              V G D + G+
Sbjct: 974  PGVPGKDGQAGQ 985



 Score = 58.5 bits (140), Expect = 2e-07
 Identities = 120/426 (28%), Positives = 162/426 (38%), Gaps = 80/426 (18%)

Query: 5203 LKGPKIKGDVPSVGLEGPDVD-----LQGPEAKIKFP----------KFSMPKIGIPGVK 5247
            L GPK  G V  +GL G   +     + GP+     P          +   P IGIPG++
Sbjct: 1006 LPGPK--GSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLR 1063

Query: 5248 MEGGGAEVHAQLPSLEGDLRGPDVKLEGPDV----SLKG-PG-VDLPSVNLSMPKVSGPD 5301
             E G   + A  P   G+ +G    +  P +     LKG PG V  P      P + G  
Sbjct: 1064 GEKGDQGI-AGFPGSPGE-KGEKGSIGIPGMPGSPGLKGSPGSVGYPG----SPGLPGEK 1117

Query: 5302 LDLNLKG----PSLKGDLDASVPSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLN 5357
             D  L G    P +KG+  A +P      PG      G K + G DG+  PG  A  K  
Sbjct: 1118 GDKGLPGLDGIPGVKGE--AGLPG----TPGPT-GPAGQKGEPGSDGI--PG-SAGEKGE 1167

Query: 5358 VGAPDVTLRG-PSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTP 5416
             G P     G P  +GD    G++  P ++ G+P +     E     P     Q G+  P
Sbjct: 1168 PGLPGRGFPGFPGAKGDKGSKGEVGFPGLA-GSPGIPGSKGEQGFMGPPGPQGQPGL--P 1224

Query: 5417 GSDLHVNA-----KGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEI 5471
            GS  H        +GPQ  G+   PG+   +  P +  P +D       VKG  G  G  
Sbjct: 1225 GSPGHATEGPKGDRGPQ--GQPGLPGLPGPMGPPGL--PGID------GVKGDKGNPGWP 1274

Query: 5472 KGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKG-- 5529
              P V G     G QG+ G    PGI  S  D+  PGV          GP+   GL+G  
Sbjct: 1275 GAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGV------PGFQGPKGLPGLQGIK 1328

Query: 5530 SEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGEGHLS 5589
             + G  G      + GP      P   + I      IKG   + G    P +   +G   
Sbjct: 1329 GDQGDQGVPGAKGLPGP----PGPPGPYDI------IKGEPGLPGPEGPPGLKGLQGLPG 1378

Query: 5590 VKGSGG 5595
             KG  G
Sbjct: 1379 PKGQQG 1384



 Score = 42.4 bits (98), Expect = 0.014
 Identities = 124/526 (23%), Positives = 166/526 (31%), Gaps = 127/526 (24%)

Query: 5206 PKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGD 5265
            P +KGD   +    P + L+G      FP       GIPG     G       LP L+G 
Sbjct: 153  PGMKGDPGEILGHVPGMLLKGERG---FP-------GIPGTPGPPG-------LPGLQGP 195

Query: 5266 LRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGP---------SLKGDLD 5316
            +  P            GP  +   + LS     G   D  + GP           KGD  
Sbjct: 196  VGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFA 255

Query: 5317 ASVPSMKVHAPGLN-LSGVGGKMQVGGDGVK-VPGIDATTKLNVGAPD----------VT 5364
                  +   PG   + GVG K + G  G +  PG D   K   G+P           + 
Sbjct: 256  TKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGD-KGEKGSPGFPGEPGYPGLIG 314

Query: 5365 LRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNA 5424
             +GP  QG+   +G    P + +G   L  +   G    P  +        PG       
Sbjct: 315  RQGP--QGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGP 372

Query: 5425 KGPQVSGELKGPGV--------DVNLKGPRISAPNVDFNLEGPKVKGSLGATGEI----- 5471
             G  V G+   PG         D    G  +  P+    L GP   GS G  G+      
Sbjct: 373  PGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPP--GSPGPPGQPGYTNG 430

Query: 5472 -----KGPTVGGGLPGI--------------------------------GVQGLEGNLQM 5494
                  GP    G PGI                                G QG  G +  
Sbjct: 431  IVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGF 490

Query: 5495 PGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPE 5554
            PG   +  D  LPG   +     + GP+   GL G                P       E
Sbjct: 491  PGQPGAKGDRGLPG---RDGVAGVPGPQGTPGLIGQ---------------PGAKGEPGE 532

Query: 5555 SDFGINLKGPKIKGGADVSGGVSAPDISLG-EGHLSVKGSGGEWKGPQVSSALNLDTSKF 5613
              F + LKG K   G     G++    S G +GH  + G     KG   S  L  +    
Sbjct: 533  FYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGP----KGSPGSVGLKGERGP- 587

Query: 5614 AGGLHFSGPKVEGGVKGGQIGLQAPGLSVSGPQGHLESGSGKVTFP 5659
             GG+ F G + + G  G       PG   +GP G      G+  FP
Sbjct: 588  PGGVGFPGSRGDTGPPG------PPGYGPAGPIG----DKGQAGFP 623



 Score = 40.0 bits (92), Expect = 0.069
 Identities = 194/753 (25%), Positives = 271/753 (35%), Gaps = 132/753 (17%)

Query: 2521 PGFKAEGPEVDVNLPKAD--VDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPK 2578
            PGF   GP+ D   P       + G K  +  P +   GP G  KG      +M      
Sbjct: 657  PGFP--GPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGP-KGVDGLPGDMGPPGTP 713

Query: 2579 ISMPDFDLHLKGPKV---KGDVDVSLPKVEGDLKGPEVD-IKGPKVDINAPDVGVQGPDW 2634
               P F+     P V   KG+  V LP ++G    P +    G K  I  P  GV G   
Sbjct: 714  -GRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVP--GVPGEHG 770

Query: 2635 HLKMPKVKMPKFSMPGFKGE-GPDGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKLKGP 2693
             +  P        + G +GE GP G   LP +   V  P V   GP     GP G    P
Sbjct: 771  AIGPP-------GLQGIRGEPGPPG---LPGS---VGSPGVPGIGPP-GARGPPGGQGPP 816

Query: 2694 KFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDVS-LPKVEGD-----LKGPEVDIKGPK 2747
                P   IK  K       L++ GPK  GD     LP + G      L G +     P 
Sbjct: 817  GLSGPP-GIKGEKGFPGFPGLDMPGPK--GDKGAQGLPGITGQSGLPGLPGQQGAPGIPG 873

Query: 2748 VDIDAPDVDVHGPDWHLKMP-KIKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVEC 2806
                  ++ V G       P  +  P   +PG KG+      + P+ D  + G K DV  
Sbjct: 874  FPGSKGEMGVMGTPGQPGSPGPVGAP--GLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGL 931

Query: 2807 PDV----------NIEGPEGKWKSPKFKMPEMHFK-------TPKISMPDIDLNLTG-PK 2848
            P            +++G +G  +  K ++  +  K       TP +   D      G P 
Sbjct: 932  PGKPGSMDKVDMGSMKGQKGD-QGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPG 990

Query: 2849 IKGDVDVTGPKVEGDLKGPE-----VDLKGPKVDIDVPDVNVQGPDWHLKMPKMKMPKFS 2903
             KGD  ++G      L GP+     + L G   +  VP   + GP     +P  K  K  
Sbjct: 991  PKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVP--GIPGPQGSPGLPGDKGAK-- 1046

Query: 2904 MPGFKAEGPEVDVNLP-----KADVDVSG----PKVDVEGPDVNIEGPEGK--LKGPKFK 2952
              G K +     + +P     K D  ++G    P    E   + I G  G   LKG    
Sbjct: 1047 --GEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGS 1104

Query: 2953 MPEMNIKAPKIPMPDFDLHLKG----PKVKGDVDISLPKVEGDLKGPEVDIRGPQVDIDV 3008
            +      +P +P    D  L G    P VKG+    LP   G   GP      P  D  +
Sbjct: 1105 VGYPG--SPGLPGEKGDKGLPGLDGIPGVKGEA--GLPGTPGP-TGPAGQKGEPGSD-GI 1158

Query: 3009 PDVGVQGPDWHLKMPKVKMPKFSMPGFKGE-GPDVDVNLP-----------KADLDVSGP 3056
            P  G  G      +P    P F  PG KG+ G   +V  P           K +    GP
Sbjct: 1159 P--GSAGEKGEPGLPGRGFPGF--PGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGP 1214

Query: 3057 KVDIDVPDV------NIEGPEGKLKGPKFK--MPEMNIKAPKISMPDIDLNLKG----PK 3104
                  P +        EGP+G  +GP+ +  +P +        +P ID  +KG    P 
Sbjct: 1215 PGPQGQPGLPGSPGHATEGPKGD-RGPQGQPGLPGLPGPMGPPGLPGID-GVKGDKGNPG 1272

Query: 3105 VKGDMDVSLPKVE-GDMKVPDV----DIKGPKVDINAPDV-DVQGPDWHLKMPKIK--MP 3156
              G   V  PK + G   +P +     I G K D+  P V   QGP     +  IK    
Sbjct: 1273 WPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQG 1332

Query: 3157 KISMPGFKG----EGPEVDVNLPKADLDVSGPK 3185
               +PG KG     GP    ++ K +  + GP+
Sbjct: 1333 DQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPE 1365



 Score = 37.4 bits (85), Expect = 0.44
 Identities = 63/233 (27%), Positives = 77/233 (33%), Gaps = 56/233 (24%)

Query: 5431 GELKGPGVDVNLKGPRISAPNVDFNLEGPK-VKGSLGATGEIKGPTVGGGLPGIGVQGLE 5489
            GE   PG+   +  P +  P      EGP+   G  G TGE   P   G     G  G  
Sbjct: 49   GERGLPGLQGVIGFPGMQGP------EGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYP 102

Query: 5490 GNLQMPGIKSSGCDVNLPGV----NVKLPTGQISGPEIKG-----------GLKGSEVGF 5534
            GN  +PGI         PG+      K   G +  P + G           G+KG     
Sbjct: 103  GNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEI 162

Query: 5535 HGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSG 5594
             G  P + +KG       P +        P   G   + G V  P  +   G     G  
Sbjct: 163  LGHVPGMLLKGERGFPGIPGT--------PGPPGLPGLQGPVGPPGFTGPPGPPGPPGPP 214

Query: 5595 GEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQAPGLSVSGPQG 5647
            GE KG                GL F GPK   G KG Q         VSGP G
Sbjct: 215  GE-KGQM--------------GLSFQGPK---GDKGDQ--------GVSGPPG 241



 Score = 35.4 bits (80), Expect = 1.7
 Identities = 94/370 (25%), Positives = 130/370 (35%), Gaps = 63/370 (17%)

Query: 209  PSGSGAASPTGSAVDIRAGAISASGPELQGAGHSKLQVTMPGIKVGGSGVNVNAKGLDLG 268
            P G    S T  A  +     S  G  L G    K    +PG +  GS      KG   G
Sbjct: 991  PKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQ--GSPGLPGDKGAK-G 1047

Query: 269  GRGGVQVPAVDISSSLGGRAVEVQGPSLESGDHGKIKFPTMKVPKFGVSTGREGQTPKAG 328
             +G    P + I    G           E GD G   FP         S G +G+  K  
Sbjct: 1048 EKGQAGPPGIGIPGLRG-----------EKGDQGIAGFPG--------SPGEKGE--KGS 1086

Query: 329  LRVSAPEVSVGHKGGKPGLTIQAPQLEVSVP-SANIEGLEGKLKGPQITG-PSLEGDLGL 386
            + +     S G KG  PG         V  P S  + G +G    P + G P ++G+ GL
Sbjct: 1087 IGIPGMPGSPGLKGS-PG--------SVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGL 1137

Query: 387  KGAK-PQGHIGVDASAPQIGGSITGPSVEVQAPDIDVQG----PGSKLNVPKMKVPKF-- 439
             G   P G  G        G  I G + E   P +  +G    PG+K +        F  
Sbjct: 1138 PGTPGPTGPAGQKGEPGSDG--IPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPG 1195

Query: 440  -----SVSGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLEGKMKGTKVKTPEMI 494
                  + G+KGE+  +    P G+  +PG  G  +       G +G+     +  P   
Sbjct: 1196 LAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGP 1255

Query: 495  IQKPKISMQDVDL-------SLGSPKLKGDIKVSAPGVQG-DVKGPQVALKGSRVDIETP 546
               P I     D        + G P  KGD     PG QG    G    + GS+ D+  P
Sbjct: 1256 PGLPGIDGVKGDKGNPGWPGAPGVPGPKGD-----PGFQGMPGIGGSPGITGSKGDMGPP 1310

Query: 547  NLEGTLTGPR 556
             + G   GP+
Sbjct: 1311 GVPG-FQGPK 1319


>gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score = 66.2 bits (160), Expect = 9e-10
 Identities = 130/457 (28%), Positives = 158/457 (34%), Gaps = 113/457 (24%)

Query: 5209 KGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGDLRG 5268
            KG++  +G+ GP    QGP          +P IG PG      G  +  Q P  +GD RG
Sbjct: 184  KGEIGPMGIPGP----QGPPGP-----HGLPGIGKPG------GPGLPGQ-PGPKGD-RG 226

Query: 5269 PDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPG 5328
            P   L GP   L+GP  D        P V GP        P + G      P   V  PG
Sbjct: 227  PK-GLPGPQ-GLRGPKGDKGFGMPGAPGVKGP--------PGMHG------PPGPVGLPG 270

Query: 5329 LNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVG 5388
            +   GV G           PG           P   L  P   G+    G I  P V   
Sbjct: 271  VGKPGVTG----------FPG-----------PQGPLGKPGAPGEPGPQGPIGVPGV--- 306

Query: 5389 APDLSLEASEGSIKLPKMKLP-QFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRI 5447
                     +G   +P +  P Q GI  PG       KG Q    L GP     +  P  
Sbjct: 307  ---------QGPPGIPGIGKPGQDGI--PGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGF 355

Query: 5448 SAPNVDFNLEG-PKVKGSLGATGEIKGPTVGG-----GLPGI-GVQGLEGNLQMPGIKSS 5500
              P  D  + G P   G  G  G I  P +GG     GLPGI G  G  G +  PG K  
Sbjct: 356  PGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGE 415

Query: 5501 GCDVNLPGVNVKLPTGQISGPEIKG-----GLKG--SEVGFHGAAPDISVKGPAFNMASP 5553
            G  V   G     P G    P ++G     G  G     G  G    I  KG A     P
Sbjct: 416  GGIVGPQG-----PPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVP 470

Query: 5554 ESDFGINLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKF 5613
                   L GPK + G     G+  P          + G GG   GP             
Sbjct: 471  GLPGVPGLLGPKGEPGIPGDQGLQGPP--------GIPGIGGP-SGP------------- 508

Query: 5614 AGGLHFSGPKVEGGVKG--GQIGLQAPGLS-VSGPQG 5647
             G     GPK E G+ G  G  G+  PG++ + GP G
Sbjct: 509  IGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPG 545



 Score = 52.0 bits (123), Expect = 2e-05
 Identities = 173/649 (26%), Positives = 232/649 (35%), Gaps = 147/649 (22%)

Query: 2474 SVPEVEGKLEVPDMNIRGPKVDVNAPDVQAPDWHLKMPKMKMP---------------KF 2518
            +VP+ +GK E+P  ++RG +     P  + P     +P   +P               K 
Sbjct: 103  AVPK-KGK-EIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKP 160

Query: 2519 SMPGFKAEGPEVDVNLPKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPK 2578
             MPG    G    + +P A  +I G K +I GP + I GP+G   GP           P 
Sbjct: 161  GMPGMP--GKPGAMGMPGAKGEI-GQKGEI-GP-MGIPGPQGP-PGPH--------GLPG 206

Query: 2579 ISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKM 2638
            I  P       GP + G       +    L GP+  ++GPK D      G+ G       
Sbjct: 207  IGKPG------GPGLPGQPGPKGDRGPKGLPGPQ-GLRGPKGD---KGFGMPGA------ 250

Query: 2639 PKVKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPKVD-IEGPDVNIEGPEGKLKGPKFKM 2697
            P VK P    PG    GP G V LP     V  P V    GP    +GP GK   P    
Sbjct: 251  PGVKGP----PGM--HGPPGPVGLP----GVGKPGVTGFPGP----QGPLGKPGAPGEPG 296

Query: 2698 PEMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDV 2757
            P+  I  P +  P        P + G   +  P  +G    P     G K +   P +  
Sbjct: 297  PQGPIGVPGVQGP--------PGIPG---IGKPGQDGIPGQP--GFPGGKGEQGLPGLP- 342

Query: 2758 HGPDWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGPEGK 2817
             GP          +P I  PGF G   D  +      +   G K  +  P +   GP G+
Sbjct: 343  -GPPG--------LPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIG--GPPGE 391

Query: 2818 WKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPEVDLKGPKVD 2877
               P    P                   GP   G +   GPK EG + GP+    GPK  
Sbjct: 392  PGLPGIPGP------------------MGPP--GAIGFPGPKGEGGIVGPQ-GPPGPK-- 428

Query: 2878 IDVPDVNVQG----PDWHLKMPKMKMPKFSMP-GFKAEGPEVDVNLPKADVDVSGPKVDV 2932
                +  +QG    P +  ++    M     P G K E  +  V        + GPK + 
Sbjct: 429  ---GEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEP 485

Query: 2933 EGP-DVNIEGPEGKLKGPKFKMPEMNIKAPKIPMPDFDLHLKGPKVKGDVDISLPKVEGD 2991
              P D  ++GP G    P    P   I  P IP P  +  L GP   G   I  P V G 
Sbjct: 486  GIPGDQGLQGPPGI---PGIGGPSGPIGPPGIPGPKGEPGLPGP--PGFPGIGKPGVAG- 539

Query: 2992 LKGP--EVDIRGPQVDIDVPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKA 3049
            L GP  +    GPQ    +P  G  GP      P V  P    P  +GE       LP  
Sbjct: 540  LHGPPGKPGALGPQGQPGLP--GPPGPPGPPGPPAVMPP---TPPPQGE------YLPDM 588

Query: 3050 DLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMP----EMNIKAPKISMP 3094
             L + G K     P       +GK  GP ++MP    E+    P +  P
Sbjct: 589  GLGIDGVK-----PPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAP 632



 Score = 45.1 bits (105), Expect = 0.002
 Identities = 83/290 (28%), Positives = 102/290 (35%), Gaps = 43/290 (14%)

Query: 5383 PKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLH-VNAK-GPQVSGELKGPGVDV 5440
            PK     P  SL   +G    P  + P      PG  +  +  K GPQ    +  PG+  
Sbjct: 105  PKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMP- 163

Query: 5441 NLKGPRISAPNVDFNLEGPKVKGSLGATGEI--------KGPTVGGGLPGIGVQGLEGNL 5492
                     P     +  P  KG +G  GEI        +GP    GLPGIG  G  G  
Sbjct: 164  -------GMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLP 216

Query: 5493 QMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMAS 5552
              PG K       LPG     P G + GP+   G KG   G  GA     VKGP   M  
Sbjct: 217  GQPGPKGDRGPKGLPG-----PQG-LRGPK---GDKG--FGMPGAP---GVKGPP-GMHG 261

Query: 5553 PESDFGINLKG-PKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDTS 5611
            P    G+   G P + G     G +  P      G     G  G    P +         
Sbjct: 262  PPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQD 321

Query: 5612 KFAGGLHFSGPKVEGGVKG-----GQIGLQAPGLSVSGPQGHLESGSGKV 5656
               G   F G K E G+ G     G  G+  PG    GP+G  + G G V
Sbjct: 322  GIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGF--PGPKG--DRGMGGV 367



 Score = 42.0 bits (97), Expect = 0.018
 Identities = 135/529 (25%), Positives = 194/529 (36%), Gaps = 83/529 (15%)

Query: 319 GREGQTPKAG-LRVSAPEVSVGHKGGKPGLTIQAPQLEVSVPSAN-IEGLEGKLKGPQIT 376
           G  G   K G + +   +  +G KG    + I  PQ     P  + + G+ GK  GP + 
Sbjct: 161 GMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQ---GPPGPHGLPGI-GKPGGPGLP 216

Query: 377 G-PSLEGDLGLKGAK-PQGHIGVDAS-------APQIGG--SITGPSVEVQAPDIDVQG- 424
           G P  +GD G KG   PQG  G           AP + G   + GP   V  P +   G 
Sbjct: 217 GQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGV 276

Query: 425 ---PGSKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLEG 481
              PG +  + K         GA GE        P G + VPGV G   +P I   G +G
Sbjct: 277 TGFPGPQGPLGK--------PGAPGEPG------PQGPIGVPGVQGPPGIPGIGKPGQDG 322

Query: 482 KMKGTKVKTPEMIIQKPKISMQDVDLSLGSPKLKGDIKVSAPGVQGD--VKGPQVALKGS 539
            + G     P     K +  +  +    G P L G  K   PG +GD  + G   AL G 
Sbjct: 323 -IPG----QPGFPGGKGEQGLPGLP---GPPGLPGIGKPGFPGPKGDRGMGGVPGAL-GP 373

Query: 540 RVDIETPNLEGTLTGPRLGSPSGKTGTCRISMSEVDLNVAAPKVKGGVDVTLPRVEGKVK 599
           R +      +G +  P +G P G+ G     +  +   +  P   G +    P+ EG + 
Sbjct: 374 RGE------KGPIGAPGIGGPPGEPG-----LPGIPGPMGPP---GAIGFPGPKGEGGIV 419

Query: 600 VPEVDVRGPKVDVSAPDVEAH--GPEWNLKMPKMKMPTFSTP-GAKGEGPDVHMTLPKGD 656
            P+    GP      P ++     P +  ++    M     P G KGE     +    G 
Sbjct: 420 GPQ----GPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGV 475

Query: 657 ISISGPKVNVEAPDVNLEGLGGKLKGPDVKLPDMSVKTPKISMPDVDLHVKGTKVKGEYD 716
             + GPK     P    +GL G    P +  P   +  P I  P  +  + G    G   
Sbjct: 476 PGLLGPKGEPGIP--GDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGP--PGFPG 531

Query: 717 VTVPKLEGELKGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSVPGFKAEGPEVDVNLPKA 776
           +  P + G L GP     A      GP     +P    P    PG  A  P       + 
Sbjct: 532 IGKPGVAG-LHGPPGKPGA-----LGPQGQPGLPGPPGPP-GPPGPPAVMPPTPPPQGEY 584

Query: 777 DVDISGPKIDVTAPDVSIEEPEGKLKGPKFKMP----EMNIKVPKISMP 821
             D+ G  ID   P  +    +GK  GP ++MP    E+    P +  P
Sbjct: 585 LPDM-GLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAP 632



 Score = 40.4 bits (93), Expect = 0.053
 Identities = 84/314 (26%), Positives = 109/314 (34%), Gaps = 50/314 (15%)

Query: 4645 GPDWHLKMPKVKMP-------KFSMPGFKGEGPDVDVNLPKADIDVSGPKVDVDVPDVNI 4697
            GP  +  + K  MP          MPG KGE        P       GP     +P +  
Sbjct: 150  GPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGK 209

Query: 4698 EGPDAK--LKGPKFKMPEMSIKAPKISMPDIDLNLKGPKVKGDVDVTLPKVEGDLKGPEA 4755
             G        GPK       +  P+         L+GPK  GD    +P   G +KGP  
Sbjct: 210  PGGPGLPGQPGPKGDRGPKGLPGPQ--------GLRGPK--GDKGFGMPGAPG-VKGPPG 258

Query: 4756 DIKGPKVDINTPDVDVHGPDWHLKMPKVKMPKFSMPGFKGE-GPDVDVSLPKADIDVSGP 4814
             + GP   +  P V   G       P  + P    PG  GE GP   + +P     V GP
Sbjct: 259  -MHGPPGPVGLPGVGKPGVTG---FPGPQGP-LGKPGAPGEPGPQGPIGVP----GVQGP 309

Query: 4815 KVDVDIPDVNIEGPDAKLKGPKFKMPEINIKAPKISIPDVDLDLKGPKVKGDFDVSVPKV 4874
                 IP +   G D     P F   +     P +  P     +  P   G      PK 
Sbjct: 310  P---GIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPG------PKG 360

Query: 4875 EGTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLHLKAP-KIGFS 4933
            +  + G    L GPR    G    +  P +  P  E   P +  P     +  P  IGF 
Sbjct: 361  DRGMGGVPGAL-GPR----GEKGPIGAPGIGGPPGEPGLPGIPGP-----MGPPGAIGFP 410

Query: 4934 GPKLEGGEVDLKGP 4947
            GPK EGG V  +GP
Sbjct: 411  GPKGEGGIVGPQGP 424



 Score = 40.4 bits (93), Expect = 0.053
 Identities = 105/367 (28%), Positives = 133/367 (36%), Gaps = 59/367 (16%)

Query: 5159 LKGPKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPSVGLE 5218
            L+GPK     G P          +  P   +  P V  P V     GP+  G +   G  
Sbjct: 236  LRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVT-GFPGPQ--GPLGKPGAP 292

Query: 5219 GPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEG-GGAEVHAQLPSLEGDLRGPDVKLEGPD 5277
            G      GP+  I  P    P  GIPG+   G  G       P  +G+   P   L GP 
Sbjct: 293  GEP----GPQGPIGVPGVQGPP-GIPGIGKPGQDGIPGQPGFPGGKGEQGLPG--LPGP- 344

Query: 5278 VSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGLN------- 5330
                 PG  LP +    P   GP  D  + G  + G L        + APG+        
Sbjct: 345  -----PG--LPGIG--KPGFPGPKGDRGMGG--VPGALGPRGEKGPIGAPGIGGPPGEPG 393

Query: 5331 LSGVGGKMQVGGDGVKVPGIDATTKLNVG--APDVTLRGPSLQGDLAVSGDIKCPKVSVG 5388
            L G+ G M   G  +  PG      + VG   P      P LQG     G +      VG
Sbjct: 394  LPGIPGPMGPPG-AIGFPGPKGEGGI-VGPQGPPGPKGEPGLQGFPGKPGFLG----EVG 447

Query: 5389 APDLSLEASEGSIKLPKMKLPQFGI-STPGSDLHVNAKG-PQVSGE--LKGPGVDVNLKG 5444
             P   +    G I  PK +  Q G+   PG    +  KG P + G+  L+GP     + G
Sbjct: 448  PP--GMRGLPGPIG-PKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGG 504

Query: 5445 PRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGIG---VQGLEGNLQMPGIKSSG 5501
            P  S P     + GPK     G  G + GP    G PGIG   V GL G    PG     
Sbjct: 505  P--SGPIGPPGIPGPK-----GEPG-LPGPP---GFPGIGKPGVAGLHGPPGKPGALGPQ 553

Query: 5502 CDVNLPG 5508
                LPG
Sbjct: 554  GQPGLPG 560


>gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]
          Length = 744

 Score = 66.2 bits (160), Expect = 9e-10
 Identities = 130/457 (28%), Positives = 158/457 (34%), Gaps = 113/457 (24%)

Query: 5209 KGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGDLRG 5268
            KG++  +G+ GP    QGP          +P IG PG      G  +  Q P  +GD RG
Sbjct: 184  KGEIGPMGIPGP----QGPPGP-----HGLPGIGKPG------GPGLPGQ-PGPKGD-RG 226

Query: 5269 PDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPG 5328
            P   L GP   L+GP  D        P V GP        P + G      P   V  PG
Sbjct: 227  PK-GLPGPQ-GLRGPKGDKGFGMPGAPGVKGP--------PGMHG------PPGPVGLPG 270

Query: 5329 LNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVG 5388
            +   GV G           PG           P   L  P   G+    G I  P V   
Sbjct: 271  VGKPGVTG----------FPG-----------PQGPLGKPGAPGEPGPQGPIGVPGV--- 306

Query: 5389 APDLSLEASEGSIKLPKMKLP-QFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRI 5447
                     +G   +P +  P Q GI  PG       KG Q    L GP     +  P  
Sbjct: 307  ---------QGPPGIPGIGKPGQDGI--PGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGF 355

Query: 5448 SAPNVDFNLEG-PKVKGSLGATGEIKGPTVGG-----GLPGI-GVQGLEGNLQMPGIKSS 5500
              P  D  + G P   G  G  G I  P +GG     GLPGI G  G  G +  PG K  
Sbjct: 356  PGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGE 415

Query: 5501 GCDVNLPGVNVKLPTGQISGPEIKG-----GLKG--SEVGFHGAAPDISVKGPAFNMASP 5553
            G  V   G     P G    P ++G     G  G     G  G    I  KG A     P
Sbjct: 416  GGIVGPQG-----PPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVP 470

Query: 5554 ESDFGINLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKF 5613
                   L GPK + G     G+  P          + G GG   GP             
Sbjct: 471  GLPGVPGLLGPKGEPGIPGDQGLQGPP--------GIPGIGGP-SGP------------- 508

Query: 5614 AGGLHFSGPKVEGGVKG--GQIGLQAPGLS-VSGPQG 5647
             G     GPK E G+ G  G  G+  PG++ + GP G
Sbjct: 509  IGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPG 545



 Score = 52.0 bits (123), Expect = 2e-05
 Identities = 173/649 (26%), Positives = 232/649 (35%), Gaps = 147/649 (22%)

Query: 2474 SVPEVEGKLEVPDMNIRGPKVDVNAPDVQAPDWHLKMPKMKMP---------------KF 2518
            +VP+ +GK E+P  ++RG +     P  + P     +P   +P               K 
Sbjct: 103  AVPK-KGK-EIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKP 160

Query: 2519 SMPGFKAEGPEVDVNLPKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPK 2578
             MPG    G    + +P A  +I G K +I GP + I GP+G   GP           P 
Sbjct: 161  GMPGMP--GKPGAMGMPGAKGEI-GQKGEI-GP-MGIPGPQGP-PGPH--------GLPG 206

Query: 2579 ISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKM 2638
            I  P       GP + G       +    L GP+  ++GPK D      G+ G       
Sbjct: 207  IGKPG------GPGLPGQPGPKGDRGPKGLPGPQ-GLRGPKGD---KGFGMPGA------ 250

Query: 2639 PKVKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPKVD-IEGPDVNIEGPEGKLKGPKFKM 2697
            P VK P    PG    GP G V LP     V  P V    GP    +GP GK   P    
Sbjct: 251  PGVKGP----PGM--HGPPGPVGLP----GVGKPGVTGFPGP----QGPLGKPGAPGEPG 296

Query: 2698 PEMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDV 2757
            P+  I  P +  P        P + G   +  P  +G    P     G K +   P +  
Sbjct: 297  PQGPIGVPGVQGP--------PGIPG---IGKPGQDGIPGQP--GFPGGKGEQGLPGLP- 342

Query: 2758 HGPDWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGPEGK 2817
             GP          +P I  PGF G   D  +      +   G K  +  P +   GP G+
Sbjct: 343  -GPPG--------LPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIG--GPPGE 391

Query: 2818 WKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPEVDLKGPKVD 2877
               P    P                   GP   G +   GPK EG + GP+    GPK  
Sbjct: 392  PGLPGIPGP------------------MGPP--GAIGFPGPKGEGGIVGPQ-GPPGPK-- 428

Query: 2878 IDVPDVNVQG----PDWHLKMPKMKMPKFSMP-GFKAEGPEVDVNLPKADVDVSGPKVDV 2932
                +  +QG    P +  ++    M     P G K E  +  V        + GPK + 
Sbjct: 429  ---GEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEP 485

Query: 2933 EGP-DVNIEGPEGKLKGPKFKMPEMNIKAPKIPMPDFDLHLKGPKVKGDVDISLPKVEGD 2991
              P D  ++GP G    P    P   I  P IP P  +  L GP   G   I  P V G 
Sbjct: 486  GIPGDQGLQGPPGI---PGIGGPSGPIGPPGIPGPKGEPGLPGP--PGFPGIGKPGVAG- 539

Query: 2992 LKGP--EVDIRGPQVDIDVPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKA 3049
            L GP  +    GPQ    +P  G  GP      P V  P    P  +GE       LP  
Sbjct: 540  LHGPPGKPGALGPQGQPGLP--GPPGPPGPPGPPAVMPP---TPPPQGE------YLPDM 588

Query: 3050 DLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMP----EMNIKAPKISMP 3094
             L + G K     P       +GK  GP ++MP    E+    P +  P
Sbjct: 589  GLGIDGVK-----PPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAP 632



 Score = 45.1 bits (105), Expect = 0.002
 Identities = 83/290 (28%), Positives = 102/290 (35%), Gaps = 43/290 (14%)

Query: 5383 PKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLH-VNAK-GPQVSGELKGPGVDV 5440
            PK     P  SL   +G    P  + P      PG  +  +  K GPQ    +  PG+  
Sbjct: 105  PKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMP- 163

Query: 5441 NLKGPRISAPNVDFNLEGPKVKGSLGATGEI--------KGPTVGGGLPGIGVQGLEGNL 5492
                     P     +  P  KG +G  GEI        +GP    GLPGIG  G  G  
Sbjct: 164  -------GMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLP 216

Query: 5493 QMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMAS 5552
              PG K       LPG     P G + GP+   G KG   G  GA     VKGP   M  
Sbjct: 217  GQPGPKGDRGPKGLPG-----PQG-LRGPK---GDKG--FGMPGAP---GVKGPP-GMHG 261

Query: 5553 PESDFGINLKG-PKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDTS 5611
            P    G+   G P + G     G +  P      G     G  G    P +         
Sbjct: 262  PPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQD 321

Query: 5612 KFAGGLHFSGPKVEGGVKG-----GQIGLQAPGLSVSGPQGHLESGSGKV 5656
               G   F G K E G+ G     G  G+  PG    GP+G  + G G V
Sbjct: 322  GIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGF--PGPKG--DRGMGGV 367



 Score = 42.0 bits (97), Expect = 0.018
 Identities = 135/529 (25%), Positives = 194/529 (36%), Gaps = 83/529 (15%)

Query: 319 GREGQTPKAG-LRVSAPEVSVGHKGGKPGLTIQAPQLEVSVPSAN-IEGLEGKLKGPQIT 376
           G  G   K G + +   +  +G KG    + I  PQ     P  + + G+ GK  GP + 
Sbjct: 161 GMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQ---GPPGPHGLPGI-GKPGGPGLP 216

Query: 377 G-PSLEGDLGLKGAK-PQGHIGVDAS-------APQIGG--SITGPSVEVQAPDIDVQG- 424
           G P  +GD G KG   PQG  G           AP + G   + GP   V  P +   G 
Sbjct: 217 GQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGV 276

Query: 425 ---PGSKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLEG 481
              PG +  + K         GA GE        P G + VPGV G   +P I   G +G
Sbjct: 277 TGFPGPQGPLGK--------PGAPGEPG------PQGPIGVPGVQGPPGIPGIGKPGQDG 322

Query: 482 KMKGTKVKTPEMIIQKPKISMQDVDLSLGSPKLKGDIKVSAPGVQGD--VKGPQVALKGS 539
            + G     P     K +  +  +    G P L G  K   PG +GD  + G   AL G 
Sbjct: 323 -IPG----QPGFPGGKGEQGLPGLP---GPPGLPGIGKPGFPGPKGDRGMGGVPGAL-GP 373

Query: 540 RVDIETPNLEGTLTGPRLGSPSGKTGTCRISMSEVDLNVAAPKVKGGVDVTLPRVEGKVK 599
           R +      +G +  P +G P G+ G     +  +   +  P   G +    P+ EG + 
Sbjct: 374 RGE------KGPIGAPGIGGPPGEPG-----LPGIPGPMGPP---GAIGFPGPKGEGGIV 419

Query: 600 VPEVDVRGPKVDVSAPDVEAH--GPEWNLKMPKMKMPTFSTP-GAKGEGPDVHMTLPKGD 656
            P+    GP      P ++     P +  ++    M     P G KGE     +    G 
Sbjct: 420 GPQ----GPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGV 475

Query: 657 ISISGPKVNVEAPDVNLEGLGGKLKGPDVKLPDMSVKTPKISMPDVDLHVKGTKVKGEYD 716
             + GPK     P    +GL G    P +  P   +  P I  P  +  + G    G   
Sbjct: 476 PGLLGPKGEPGIP--GDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGP--PGFPG 531

Query: 717 VTVPKLEGELKGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSVPGFKAEGPEVDVNLPKA 776
           +  P + G L GP     A      GP     +P    P    PG  A  P       + 
Sbjct: 532 IGKPGVAG-LHGPPGKPGA-----LGPQGQPGLPGPPGPP-GPPGPPAVMPPTPPPQGEY 584

Query: 777 DVDISGPKIDVTAPDVSIEEPEGKLKGPKFKMP----EMNIKVPKISMP 821
             D+ G  ID   P  +    +GK  GP ++MP    E+    P +  P
Sbjct: 585 LPDM-GLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAP 632



 Score = 40.4 bits (93), Expect = 0.053
 Identities = 84/314 (26%), Positives = 109/314 (34%), Gaps = 50/314 (15%)

Query: 4645 GPDWHLKMPKVKMP-------KFSMPGFKGEGPDVDVNLPKADIDVSGPKVDVDVPDVNI 4697
            GP  +  + K  MP          MPG KGE        P       GP     +P +  
Sbjct: 150  GPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGK 209

Query: 4698 EGPDAK--LKGPKFKMPEMSIKAPKISMPDIDLNLKGPKVKGDVDVTLPKVEGDLKGPEA 4755
             G        GPK       +  P+         L+GPK  GD    +P   G +KGP  
Sbjct: 210  PGGPGLPGQPGPKGDRGPKGLPGPQ--------GLRGPK--GDKGFGMPGAPG-VKGPPG 258

Query: 4756 DIKGPKVDINTPDVDVHGPDWHLKMPKVKMPKFSMPGFKGE-GPDVDVSLPKADIDVSGP 4814
             + GP   +  P V   G       P  + P    PG  GE GP   + +P     V GP
Sbjct: 259  -MHGPPGPVGLPGVGKPGVTG---FPGPQGP-LGKPGAPGEPGPQGPIGVP----GVQGP 309

Query: 4815 KVDVDIPDVNIEGPDAKLKGPKFKMPEINIKAPKISIPDVDLDLKGPKVKGDFDVSVPKV 4874
                 IP +   G D     P F   +     P +  P     +  P   G      PK 
Sbjct: 310  P---GIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPG------PKG 360

Query: 4875 EGTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLHLKAP-KIGFS 4933
            +  + G    L GPR    G    +  P +  P  E   P +  P     +  P  IGF 
Sbjct: 361  DRGMGGVPGAL-GPR----GEKGPIGAPGIGGPPGEPGLPGIPGP-----MGPPGAIGFP 410

Query: 4934 GPKLEGGEVDLKGP 4947
            GPK EGG V  +GP
Sbjct: 411  GPKGEGGIVGPQGP 424



 Score = 40.4 bits (93), Expect = 0.053
 Identities = 105/367 (28%), Positives = 133/367 (36%), Gaps = 59/367 (16%)

Query: 5159 LKGPKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPSVGLE 5218
            L+GPK     G P          +  P   +  P V  P V     GP+  G +   G  
Sbjct: 236  LRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVT-GFPGPQ--GPLGKPGAP 292

Query: 5219 GPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEG-GGAEVHAQLPSLEGDLRGPDVKLEGPD 5277
            G      GP+  I  P    P  GIPG+   G  G       P  +G+   P   L GP 
Sbjct: 293  GEP----GPQGPIGVPGVQGPP-GIPGIGKPGQDGIPGQPGFPGGKGEQGLPG--LPGP- 344

Query: 5278 VSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGLN------- 5330
                 PG  LP +    P   GP  D  + G  + G L        + APG+        
Sbjct: 345  -----PG--LPGIG--KPGFPGPKGDRGMGG--VPGALGPRGEKGPIGAPGIGGPPGEPG 393

Query: 5331 LSGVGGKMQVGGDGVKVPGIDATTKLNVG--APDVTLRGPSLQGDLAVSGDIKCPKVSVG 5388
            L G+ G M   G  +  PG      + VG   P      P LQG     G +      VG
Sbjct: 394  LPGIPGPMGPPG-AIGFPGPKGEGGI-VGPQGPPGPKGEPGLQGFPGKPGFLG----EVG 447

Query: 5389 APDLSLEASEGSIKLPKMKLPQFGI-STPGSDLHVNAKG-PQVSGE--LKGPGVDVNLKG 5444
             P   +    G I  PK +  Q G+   PG    +  KG P + G+  L+GP     + G
Sbjct: 448  PP--GMRGLPGPIG-PKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGG 504

Query: 5445 PRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGIG---VQGLEGNLQMPGIKSSG 5501
            P  S P     + GPK     G  G + GP    G PGIG   V GL G    PG     
Sbjct: 505  P--SGPIGPPGIPGPK-----GEPG-LPGPP---GFPGIGKPGVAGLHGPPGKPGALGPQ 553

Query: 5502 CDVNLPG 5508
                LPG
Sbjct: 554  GQPGLPG 560


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 65.9 bits (159), Expect = 1e-09
 Identities = 139/499 (27%), Positives = 188/499 (37%), Gaps = 91/499 (18%)

Query: 5205 GPKIKGDVPSVGLEGPD--VDLQGPEAKIKFPKFSMPK--IGIPGVKMEGG-----GAEV 5255
            GPK+  D P  GL G      L+G + +        PK   G+PG+K + G     G + 
Sbjct: 2091 GPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDG 2150

Query: 5256 HAQLPSLEGDLRGPDVK-----LEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPS 5310
            +  LP   G + GP+ K       GP   + G G   P      P ++GP      +GPS
Sbjct: 2151 NPGLPGERG-MAGPEGKPGLQGPRGPPGPVGGHGDPGPP---GAPGLAGP---AGPQGPS 2203

Query: 5311 -LKGDLDASVPSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPS 5369
             LKG+   + P      PG  L+G  G        V +PG    + L VG        P 
Sbjct: 2204 GLKGEPGETGP------PGRGLTGPTG-------AVGLPGPPGPSGL-VGPQG----SPG 2245

Query: 5370 LQGDLAVSGDIKCP---KVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKG 5426
            L G +  +G    P     S    D       GS  LP    P+      G+        
Sbjct: 2246 LPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGL 2305

Query: 5427 PQVSGELKGPGVDVNLKGPRISAPNV--DFNLEGPK-VKGSLGATGE-----------IK 5472
            P   GE   PG    L G  +  P    D  L GP+  KG  G  GE             
Sbjct: 2306 PGAKGEKGAPG---GLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAP 2362

Query: 5473 GPTVGGGLPGIGV---------QGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQIS--GP 5521
            GP    G PG+GV          G++G+L +PG+  +   V  PG     P G++   GP
Sbjct: 2363 GPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTG--PRGEMGQPGP 2420

Query: 5522 EIKGGLKGSEVGFHGAAPDISVKGPAFNMASP--------ESDFGINLKGPK-IKGGADV 5572
              + GL G   G  G    +   GP  ++  P        + D G+ L GP+  +G   +
Sbjct: 2421 SGERGLAGPP-GREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGI 2479

Query: 5573 SGGVSAPDISLGEGHLSVKGSGGE--WKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKG 5630
             G    P      G     GS GE   KG   S+ L  D    A  L   GP+   G K 
Sbjct: 2480 RGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPR---GAK- 2535

Query: 5631 GQIGLQAP-GL-SVSGPQG 5647
            G +G + P GL    GP+G
Sbjct: 2536 GDMGERGPRGLDGDKGPRG 2554



 Score = 61.6 bits (148), Expect = 2e-08
 Identities = 149/540 (27%), Positives = 201/540 (37%), Gaps = 89/540 (16%)

Query: 5153 PKIEGDLKGPKVQANLGAPDINIEGLDAKVKTPSFGISAPQVS--IPDVNVNLKGPKIKG 5210
            PK+  D  GP +    G P +      AK +  S G   P+    +P +  +   P  +G
Sbjct: 2092 PKVSVDEPGPGLSGEQGPPGLK----GAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRG 2147

Query: 5211 DVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGDL--RG 5268
               + GL G +  + GPE K   P    P+ G PG  + G G       P L G    +G
Sbjct: 2148 QDGNPGLPG-ERGMAGPEGK---PGLQGPR-GPPG-PVGGHGDPGPPGAPGLAGPAGPQG 2201

Query: 5269 PD-VKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSM-KVHA 5326
            P  +K E  +    G G+  P+  + +P   GP     L GP     L   V    K  A
Sbjct: 2202 PSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPS---GLVGPQGSPGLPGQVGETGKPGA 2258

Query: 5327 PGLNLSGVGGKMQVGGDGVKVPGIDATTKLN-----------VGAPDVTLRG-PSLQGDL 5374
            PG +  G  GK    G     PG+  +  L             GAP   + G P  +G+ 
Sbjct: 2259 PGRD--GASGKDGDRGS----PGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEK 2312

Query: 5375 AVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGI-STPGSDLHVNAKGPQVSGEL 5433
               G +    V  G P    +      +  K +  + G    PG D    A GP+  G  
Sbjct: 2313 GAPGGLAGDLV--GEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPK--GFK 2368

Query: 5434 KGPGVDVNLKGPRISAPNV--DFNLEG----PKVKGSLGATGE--------------IKG 5473
              PGV V         P V  D  L G    P V G  G TG               + G
Sbjct: 2369 GDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAG 2428

Query: 5474 PTVGGGLPG-IGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEV 5532
            P    G+PG +G  G  G++  PG      D   PGV +  P G+   P I+G     E 
Sbjct: 2429 PPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRG-----ED 2483

Query: 5533 GFHGAAPDISVKGPAFNMA--SPESDFG-INLKGPKIKGGADVSGGVSAPDISLGE-GHL 5588
            G  G      + GP  +      + D G   LKG   KG + V  G   P  + G+ G  
Sbjct: 2484 GRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGD--KGDSAVILGPPGPRGAKGDMGER 2541

Query: 5589 SVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQAPGL-SVSGPQG 5647
              +G  G+ KGP+  +          G     G K E G K G  GL  PGL  + GPQG
Sbjct: 2542 GPRGLDGD-KGPRGDN----------GDPGDKGSKGEPGDK-GSAGL--PGLRGLLGPQG 2587



 Score = 57.0 bits (136), Expect = 5e-07
 Identities = 130/490 (26%), Positives = 168/490 (34%), Gaps = 103/490 (21%)

Query: 5208 IKGDVPSVGLEGP------DVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPS 5261
            +KGD    G +GP      +    GP      P     K GIPG+    GG    A  P 
Sbjct: 2004 LKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPG----KPGIPGLPGRAGGVG-EAGRPG 2058

Query: 5262 LEGDLRGPDVKL--EGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASV 5319
              G+ RG   +   +G D     PG   P      P   GP + ++  GP L G+     
Sbjct: 2059 ERGE-RGEKGERGEQGRDGPPGLPGTPGP------PGPPGPKVSVDEPGPGLSGEQGP-- 2109

Query: 5320 PSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRG-PSLQGDLAVSG 5378
                   PGL     G K + G +G + P  D              RG P ++GD    G
Sbjct: 2110 -------PGLK----GAKGEPGSNGDQGPKGD--------------RGVPGIKGDRGEPG 2144

Query: 5379 DIKCPKVSVGAPDL----SLEASEGSIKLPKMKLPQFGIS------TPGSDLHVNAKGPQ 5428
                P+   G P L     +   EG   L   + P   +        PG+       GPQ
Sbjct: 2145 ----PRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQ 2200

Query: 5429 VSGELKGPGVDVNLKGPRISAPNVDFNLEGPK-------VKGSLGATGEIKGPTVGGGLP 5481
                LKG   +    G  ++ P     L GP         +GS G  G++ G T   G P
Sbjct: 2201 GPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQV-GETGKPGAP 2259

Query: 5482 GI-GVQGLEGNLQMPGIKSSGCDVNLPG-VNVKLPTGQISGPE--------------IKG 5525
            G  G  G +G+   PG+  S     LPG V  K   G    P                 G
Sbjct: 2260 GRDGASGKDGDRGSPGVPGSP---GLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPG 2316

Query: 5526 GLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGE 5585
            GL G  VG  GA  D  + GP                G     G D   G   P    G+
Sbjct: 2317 GLAGDLVGEPGAKGDRGLPGPRGEKGE------AGRAGEPGDPGEDGQKGAPGPKGFKGD 2370

Query: 5586 GHLSVKGSGGEWKGPQVSSALNLDTSKFAGGL----HFSGPKVEGGVKG--GQIGLQAP- 5638
              + V GS G    P V   L L     A G+      +GP+ E G  G  G+ GL  P 
Sbjct: 2371 PGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPP 2430

Query: 5639 -GLSVSGPQG 5647
                + GP G
Sbjct: 2431 GREGIPGPLG 2440



 Score = 56.6 bits (135), Expect = 7e-07
 Identities = 111/383 (28%), Positives = 142/383 (37%), Gaps = 65/383 (16%)

Query: 208  LPSGSGAASPTGSAVDIRAGAISASGPELQGAGHSKLQVTMPGIK-VGGSGVNVNAKGLD 266
            LP   G A P G     + G     GP     GH       PG   + G        GL 
Sbjct: 2154 LPGERGMAGPEG-----KPGLQGPRGPPGPVGGHG--DPGPPGAPGLAGPAGPQGPSGLK 2206

Query: 267  LGGRGGVQVPAVDISSSLGGRAVEVQGPSLESGDHGKIKFPTM--KVPKFGV--STGREG 322
             G  G    P   ++   G  AV + GP   SG  G    P +  +V + G   + GR+G
Sbjct: 2207 -GEPGETGPPGRGLTGPTG--AVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDG 2263

Query: 323  QTPKAGLRVSAPEVS--------VGHKGGKPGLTIQAPQLEVSVPSANIE-GLEGKLKGP 373
             + K G R S P V         VG KG +PG T    Q  V +P A  E G  G L G 
Sbjct: 2264 ASGKDGDRGS-PGVPGSPGLPGPVGPKG-EPGPTGAPGQAVVGLPGAKGEKGAPGGLAGD 2321

Query: 374  QITGPSLEGDLGLKGAKPQGHIGVDASAPQIGGSITGPSVEVQAPDIDVQGPGSKLNVPK 433
             +  P  +GD GL G  P+G  G    A + G             D     PG K     
Sbjct: 2322 LVGEPGAKGDRGLPG--PRGEKGEAGRAGEPGDP---------GEDGQKGAPGPK----- 2365

Query: 434  MKVPKFSVSGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEI--ATG--------GLEGKM 483
                     G KG+  G+ V    G    PGV GD+ LP +  A G        G  G+M
Sbjct: 2366 ---------GFKGDP-GVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEM 2415

Query: 484  KGTKVKTPEMIIQKPKISMQDVDLSLGSPKLKGDI-KVSAPGVQGDVKGPQVALKGSRVD 542
             G    + E  +  P    + +   LG P   G +    A G++GD   P V L G R +
Sbjct: 2416 -GQPGPSGERGLAGPP-GREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGE 2473

Query: 543  IETPNLEGTLTGPRLGSPSGKTG 565
               P + G    P    P G TG
Sbjct: 2474 RGEPGIRGEDGRPGQEGPRGLTG 2496



 Score = 55.8 bits (133), Expect = 1e-06
 Identities = 210/821 (25%), Positives = 279/821 (33%), Gaps = 197/821 (23%)

Query: 4813 GPKVDVDIPDVNIEGPDAK--LKGPKFKMPEINIKAPK--ISIPDVDLDLKGPKVKG-DF 4867
            GPKV VD P   + G      LKG K +      + PK    +P +  D   P  +G D 
Sbjct: 2091 GPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDG 2150

Query: 4868 DVSVPKVEGTLKGPE--VDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLHL 4925
            +  +P   G + GPE    L+GPR    GP   + G     P     AP +  P      
Sbjct: 2151 NPGLPGERG-MAGPEGKPGLQGPR----GPPGPVGGHGDPGPP---GAPGLAGP------ 2196

Query: 4926 KAPKIGFSGPKLEGGEVDLKGPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKFGFGAK 4985
             A   G SG K E GE    G  +  P+  V +  P     GP              G  
Sbjct: 2197 -AGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPP----GPS-------------GLV 2238

Query: 4986 SPKADIKSPSLDVTVPEAELNLETPEISVGGKGKKSKFKMPKIHMSGPKIKAKKQGFDLN 5045
             P+    SP L   V E            G  G+                 A  +  D  
Sbjct: 2239 GPQG---SPGLPGQVGETG--------KPGAPGRDG---------------ASGKDGDRG 2272

Query: 5046 VPGGEIDASLKAPDVDVNIAGPDAA---LKVDVKSPKTKKTMFGKMYFPDVEFDIKSPKF 5102
             PG      L  P       GP  A     V +   K +K   G +   D+   +  P  
Sbjct: 2273 SPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLA-GDL---VGEPGA 2328

Query: 5103 KAEAPLPSPKLE-GELQAPDLELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGDLKG 5161
            K +  LP P+ E GE          P    E     A  PK    D  + VP   G    
Sbjct: 2329 KGDRGLPGPRGEKGEAG----RAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGP 2384

Query: 5162 PKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSI----PDVNVNLKGPKIKGDVPS-VG 5216
            P V+ +LG P   + G    V  P  G + P+  +    P     L GP  +  +P  +G
Sbjct: 2385 PGVKGDLGLP--GLPGAPGVVGFP--GQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLG 2440

Query: 5217 LEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGP 5276
              GP   +  P A         P +G+PG + E G           E  +RG D +    
Sbjct: 2441 PPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERG-----------EPGIRGEDGR---- 2485

Query: 5277 DVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLSGVGG 5336
                  PG + P        ++GP        P  +G+                    G 
Sbjct: 2486 ------PGQEGPR------GLTGP--------PGSRGER-------------------GE 2506

Query: 5337 KMQVGGDGVKVPGIDATTKLNVGAP-----DVTLRGP-SLQGDLAVSGDIKCP--KVSVG 5388
            K  VG  G+K    D+   L    P     D+  RGP  L GD    GD   P  K S G
Sbjct: 2507 KGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKG 2566

Query: 5389 APDLSLEASEGSIKLPKMK---LPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGP 5445
             P       +GS  LP ++    PQ      G      + G      ++G   DV   GP
Sbjct: 2567 EP-----GDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGP 2621

Query: 5446 RISAPNVDFNLEGPK-VKGSLGATGEIKGPTVGGGLPG-IGVQGLEGNLQMPGIKSSGCD 5503
            R         L+G + VKG+ G  GE KG     G PG  G+ G +G +  PG+      
Sbjct: 2622 R--------GLKGERGVKGACGLDGE-KGDKGEAGPPGRPGLAGHKGEMGEPGV------ 2666

Query: 5504 VNLPGVNVKLPTGQISGPEIKG--GLKGSEVGFHGAAPDISVKGPAFNMASPESDFGI-N 5560
                        GQ   P  +G  G KG   GF G       +G      +P    GI  
Sbjct: 2667 -----------PGQSGAPGKEGLIGPKGDR-GFDGQPGPKGDQGEKGERGTP----GIGG 2710

Query: 5561 LKGPKIKGGADVSGGVSAPDISLG-EGHLSVKGSGGEWKGP 5600
              GP    G D S G   P  S+G  G   ++G  GE +GP
Sbjct: 2711 FPGP---SGNDGSAGPPGPPGSVGPRGPEGLQGQKGE-RGP 2747



 Score = 50.1 bits (118), Expect = 7e-05
 Identities = 142/506 (28%), Positives = 184/506 (36%), Gaps = 85/506 (16%)

Query: 5161 GPKVQAN-LGAPDINIEGLDAKV--KTPSFGISAPQVSIPDVNVN--LKGPK-IKGDVPS 5214
            GPK +    GAP   + GL      K    G++   V  P    +  L GP+  KG+   
Sbjct: 2287 GPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGR 2346

Query: 5215 VGLEG-PDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKL 5273
             G  G P  D Q      K  K   P +G+PG     G        P ++GDL  P   L
Sbjct: 2347 AGEPGDPGEDGQKGAPGPKGFKGD-PGVGVPGSPGPPGP-------PGVKGDLGLPG--L 2396

Query: 5274 EGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGP----SLKGDLDASVPSMKVHAPGL 5329
             G    +  PG   P   +  P   GP  +  L GP     + G L    P   V  PG 
Sbjct: 2397 PGAPGVVGFPGQTGPRGEMGQP---GPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGA 2453

Query: 5330 NLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGA 5389
            +    G K   G  GV +PG           P      P ++G+    G  + P+   G 
Sbjct: 2454 S----GLKGDKGDPGVGLPG-----------PRGERGEPGIRGEDGRPGQ-EGPRGLTGP 2497

Query: 5390 PDLSLEASE----GSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGP 5445
            P    E  E    GS  L   K     I  P       AKG    GE    G+D + KGP
Sbjct: 2498 PGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPR--GAKGDM--GERGPRGLDGD-KGP 2552

Query: 5446 RISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPG----IGVQGLEGNLQMPGIKSSG 5501
            R    N D     P  KGS G  G+ KG     GLPG    +G QG  G   +PG   S 
Sbjct: 2553 R--GDNGD-----PGDKGSKGEPGD-KG---SAGLPGLRGLLGPQGQPGAAGIPGDPGSP 2601

Query: 5502 CDVNLPGVNVKLPTGQISGPE-IKG--GLKGSEVGFHGAAPDISVKGPAFNMASPESDFG 5558
                +PG+  +       GP  +KG  G+KG+  G  G   D    GP            
Sbjct: 2602 GKDGVPGIRGEKGDVGFMGPRGLKGERGVKGA-CGLDGEKGDKGEAGPPGRPGLAGHKGE 2660

Query: 5559 INLKGPKIKGGADVSGGVSAPDISLG-EGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGL 5617
            +   G   + GA    G+  P    G +G    KG  GE KG + +  +        GG 
Sbjct: 2661 MGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGE-KGERGTPGI--------GG- 2710

Query: 5618 HFSGPKVEGGVKG-----GQIGLQAP 5638
             F GP    G  G     G +G + P
Sbjct: 2711 -FPGPSGNDGSAGPPGPPGSVGPRGP 2735



 Score = 43.1 bits (100), Expect = 0.008
 Identities = 93/331 (28%), Positives = 115/331 (34%), Gaps = 42/331 (12%)

Query: 5339 QVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCP--KVSVGAPDLSLEA 5396
            + G  G + P   AT K   G P    R P   G     G    P  K S G P    + 
Sbjct: 1279 RTGAPGPQGPPGSATAKGERGFPGADGR-PGSPGRAGNPGTPGAPGLKGSPGLPGPRGDP 1337

Query: 5397 SEGSIKLPKMKLPQFGISTPGSDLHV-NAKGPQVSGELKGPGVDVNLKGPR----ISAPN 5451
             E   + PK          PG+   V   +GP + G    PG      GPR       P 
Sbjct: 1338 GERGPRGPK--------GEPGAPGQVIGGEGPGLPGRKGDPGPS-GPPGPRGPLGDPGPR 1388

Query: 5452 VDFNLEGPKVKGSLGATGE--IKGPTVGG------GLPGI-GVQGLEGNLQMPGIKSSGC 5502
                L G  +KG  G  GE    GP  GG      GLPG+ G  G +G +  PG K    
Sbjct: 1389 GPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKG 1448

Query: 5503 DV--NLPGVNVKLPTGQISGPEIKGGLKG--SEVGFHGAAPDISVKGPAFNMASPESDFG 5558
            D     PG+  +  +    GP    G  G   + GF G   +   KG       P     
Sbjct: 1449 DSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKG---ERGPPGPAGS 1505

Query: 5559 INLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLH 5618
              L G   + GA    G   P    GE     KG  G    P V            G + 
Sbjct: 1506 RGLPGVAGRPGAKGPEGPPGPTGRQGE-----KGEPGRPGDPAVVGPAVAGPKGEKGDVG 1560

Query: 5619 FSGPKVEGGVKG--GQIGLQAPGLSVSGPQG 5647
             +GP+   GV+G  G  GL  PG    GP+G
Sbjct: 1561 PAGPRGATGVQGERGPPGLVLPG--DPGPKG 1589



 Score = 40.4 bits (93), Expect = 0.053
 Identities = 138/563 (24%), Positives = 195/563 (34%), Gaps = 97/563 (17%)

Query: 292  QGPSLESGDHGKIKFPTMKVP-KFGVSTGREGQTPKAGLRVSAPEVSVGHKG--GKPGLT 348
            +GP  +SG+ G    P  + P  F    G +G     G +   P +++G +G  G  GL 
Sbjct: 1978 RGPKGDSGEQGP---PGKEGPIGFPGERGLKGDRGDPGPQ-GPPGLALGERGPPGPSGLA 2033

Query: 349  IQAPQLEVSVPSANIEGLEGKLKGPQITG-PSLEGDLGLKGAKPQGHIGVDASAPQIGGS 407
             +  +         I GL G+  G    G P   G+ G KG +  G  G D   P + G+
Sbjct: 2034 GEPGK-------PGIPGLPGRAGGVGEAGRPGERGERGEKGER--GEQGRDGP-PGLPGT 2083

Query: 408  ITGPSVEVQAPDIDVQGPG--SKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVPGV 465
               P        +D  GPG   +   P +K       GAKGE        P G+  VPG+
Sbjct: 2084 PGPPGPPGPKVSVDEPGPGLSGEQGPPGLK-------GAKGEPGSNGDQGPKGDRGVPGI 2136

Query: 466  SGDVSLP----EIATGGLEGKMKGTKVKTPEMIIQKPK-----ISMQDVDLSLGSPKLKG 516
             GD   P    +    GL G+ +G      +  +Q P+     +         G+P L G
Sbjct: 2137 KGDRGEPGPRGQDGNPGLPGE-RGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAG 2195

Query: 517  DIKVSAP----GVQGDVKGPQVALKGSRVDIETPNLEGT--LTGPRLGSPS-----GKTG 565
                  P    G  G+   P   L G    +  P   G   L GP+ GSP      G+TG
Sbjct: 2196 PAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQ-GSPGLPGQVGETG 2254

Query: 566  ----TCRISMSEVDLNVAAPKVKGGVDVT-------LPRVEGKVKVPEVDVRGPKVDVSA 614
                  R   S  D +  +P V G   +         P   G      V + G K +  A
Sbjct: 2255 KPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGA 2314

Query: 615  PDVEAHGPEWNLKMPKMKMPTFSTPGAKGEGPDVHMTLPKGD------ISISGPKVNVEA 668
            P     G   +L            PG +GE  +       GD          GPK     
Sbjct: 2315 PG----GLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGD 2370

Query: 669  PDVNLEGLGGKLKGPDVK----LPDMSVKTPKISMPDVDLHVKGTKVKGEYDVTVPKLEG 724
            P V + G  G    P VK    LP +      +  P        T  +GE     P  E 
Sbjct: 2371 PGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPG------QTGPRGEMGQPGPSGER 2424

Query: 725  ELKGP--KVDIDAPDVDVHGPDWHLKMPKMKMPKFSVPGFKAEGPEVDVNLPKADVDISG 782
             L GP  +  I  P +   GP   +  P          G K +  +  V LP       G
Sbjct: 2425 GLAGPPGREGIPGP-LGPPGPPGSVGPP-------GASGLKGDKGDPGVGLP-------G 2469

Query: 783  PKIDVTAPDVSIEEPEGKLKGPK 805
            P+ +   P +  E+     +GP+
Sbjct: 2470 PRGERGEPGIRGEDGRPGQEGPR 2492



 Score = 40.0 bits (92), Expect = 0.069
 Identities = 54/176 (30%), Positives = 72/176 (40%), Gaps = 26/176 (14%)

Query: 5426 GPQVSGELKGPGVDVNLKGPRISAPNVD--FNLEG-PKVKGSLGATGEI--KGPTVGGGL 5480
            GPQ    ++GP  +   +GP    P +D    L+G P   G  G  G     G     GL
Sbjct: 1755 GPQGDPGVRGPAGEKGDRGP----PGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGL 1810

Query: 5481 PGI-GVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAP 5539
            PG+ G QGL G    PG+     +   PG+N K   G+   P  + G KG E G  GA+ 
Sbjct: 1811 PGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGK--NGEPGDPG-EDGRKG-EKGDSGASG 1866

Query: 5540 DISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGG 5595
                 GP     +P       + GP  +G   + G V  P    G+G   V G  G
Sbjct: 1867 REGRDGPKGERGAP------GILGP--QGPPGLPGPVGPP----GQGFPGVPGGTG 1910



 Score = 39.7 bits (91), Expect = 0.090
 Identities = 126/488 (25%), Positives = 162/488 (33%), Gaps = 96/488 (19%)

Query: 5203 LKGPKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMP-------KIGIPGVKMEGGGAEV 5255
            L G  +KGD    G  GP    +G  A  +     +P        +G PG K E G +E 
Sbjct: 1393 LPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSED 1452

Query: 5256 HAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGP----SL 5311
             A  P L G    P    +GP    +GP           P   GP  D    GP      
Sbjct: 1453 GA--PGLPGQPGSPGE--QGP----RGP-----------PGAIGPKGDRGFPGPLGEAGE 1493

Query: 5312 KGDLDASVPSMKVHAPGLNLSGVGGKMQVGG-DGVKVPGIDATTKLNVGAP-DVTLRGPS 5369
            KG+     P     A    L GV G+    G +G   P      K   G P D  + GP+
Sbjct: 1494 KGERGPPGP-----AGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPA 1548

Query: 5370 LQGDLAVSGDI--KCPKVSVGA------PDLSLEAS---------EGSIKLPKMKLPQFG 5412
            + G     GD+    P+ + G       P L L             G I L     P   
Sbjct: 1549 VAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGD 1608

Query: 5413 ISTPGSDLHVNAKGPQVSGELKGPGVDVNLKG-------PRISAPNVDFNLEG-PKVKGS 5464
               PG        GP      +G   +V  KG       P +     +  L G P V+G 
Sbjct: 1609 SGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGP 1668

Query: 5465 LGATGEIKGPTVGG--GLPG-IGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGP 5521
            +G  G+   P   G  G PG  G +G  G    PG      D   PG   K   G   G 
Sbjct: 1669 VGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTG-PGAREKGEPGD-RGQ 1726

Query: 5522 EIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDI 5581
            E   G KG + G  GA  +  ++G       P+ D       P ++G A   G    P +
Sbjct: 1727 EGPRGPKG-DPGLPGAPGERGIEG-FRGPPGPQGD-------PGVRGPAGEKGDRGPPGL 1777

Query: 5582 SLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKG--GQIGLQAPG 5639
              G   L  K       GP              G    +G     G+ G  G+ GL  P 
Sbjct: 1778 D-GRSGLDGKPGAAGPSGPN-------------GAAGKAGDPGRDGLPGLRGEQGLPGP- 1822

Query: 5640 LSVSGPQG 5647
               SGP G
Sbjct: 1823 ---SGPPG 1827



 Score = 38.9 bits (89), Expect = 0.15
 Identities = 125/506 (24%), Positives = 166/506 (32%), Gaps = 93/506 (18%)

Query: 208  LPSGSGAASPTGS-------------AVDIRAGAISASG-PELQGAGHSKLQVTMPGIKV 253
            LP  +GA  P G                D R G+   +G P   GA   K    +PG + 
Sbjct: 1276 LPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRG 1335

Query: 254  G-------GSGVNVNAKGLDLGGRGGVQVPAVDISSSLGGRAVEVQGPSLESGDHGKIKF 306
                    G      A G  +GG G            L GR  +  GPS   G  G +  
Sbjct: 1336 DPGERGPRGPKGEPGAPGQVIGGEG----------PGLPGRKGD-PGPSGPPGPRGPLGD 1384

Query: 307  PTMKVPKFGVSTGREGQTPKAGLRVSAPEVSVGHKGGKPGLT----IQAPQLEVSVPSAN 362
            P  + P     T  +G     G R        G   G+PGL        PQ  V  P   
Sbjct: 1385 PGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKK 1444

Query: 363  IEGLEGKLKGPQITG-PSLEGDLGLKGAKPQGHIGVDASAPQIGGSITGPSVEV-QAPDI 420
             E  + +   P + G P   G+ G +G  P G IG     P+      GP  E  +  + 
Sbjct: 1445 GEKGDSEDGAPGLPGQPGSPGEQGPRG--PPGAIG-----PKGDRGFPGPLGEAGEKGER 1497

Query: 421  DVQGPGSKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLE 480
               GP     +P +        GAKG E     T   GE   PG  GD ++   A  G +
Sbjct: 1498 GPPGPAGSRGLPGVA----GRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPK 1553

Query: 481  GKMKGTKVKTPEMII------QKPKISMQDVDLSLGSPKLKGDIKVSA----------PG 524
            G+        P            P + +       G P  +G I ++           PG
Sbjct: 1554 GEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPG 1613

Query: 525  VQGDVKGP----QVALKGSRVDIETPNLEGTLTGPRLGSPSGKTGTCRISMSEVDLNVAA 580
             +GD   P     V  +G   ++     EG    P L   +G+ G              A
Sbjct: 1614 EKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGL-----------RGA 1662

Query: 581  PKVKGGV----DVTLPRVEGKVKVPEVDVRGPKVDVSAPDVEAHGPEWNLKMPKMKMPTF 636
            P V+G V    D   P  +G+   P     GPK D   P     GP   L          
Sbjct: 1663 PGVRGPVGEKGDQGDPGEDGRNGSP--GSSGPKGDRGEPG--PPGPPGRLVDTGPGAREK 1718

Query: 637  STPGAKG-EGPDVHMTLPKGDISISG 661
              PG +G EGP      PKGD  + G
Sbjct: 1719 GEPGDRGQEGP----RGPKGDPGLPG 1740



 Score = 38.1 bits (87), Expect = 0.26
 Identities = 162/664 (24%), Positives = 216/664 (32%), Gaps = 160/664 (24%)

Query: 5205 GPKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEG 5264
            G + KG+    G EGP    +GP+     P       G PG +    G E     P  +G
Sbjct: 1714 GAREKGEPGDRGQEGP----RGPKGDPGLP-------GAPGER----GIEGFRGPPGPQG 1758

Query: 5265 D--LRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKG----------PSLK 5312
            D  +RGP     G       PG+D  S     P  +GP       G          P L+
Sbjct: 1759 DPGVRGP----AGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLR 1814

Query: 5313 GDLDASVPSMKVHAPGL----NLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGP 5368
            G+     PS     PG        G+ GK    GD    PG D                 
Sbjct: 1815 GEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGD----PGEDGRK-------------- 1856

Query: 5369 SLQGDLAVSG--DIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKG 5426
              +GD   SG      PK   GAP +     +G   LP    P  G   PG       KG
Sbjct: 1857 GEKGDSGASGREGRDGPKGERGAPGIL--GPQGPPGLPGPVGPP-GQGFPGVPGGTGPKG 1913

Query: 5427 PQVSGELKG----PGVDVNLKGPRISAPNVDFNLEGPKVKGS-LGATGEIKGPTVGGGLP 5481
             +     KG    PG +  L+G   S PNVD  LE   +K S L    E    + G  LP
Sbjct: 1914 DRGETGSKGEQGLPG-ERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLP 1972

Query: 5482 -------------GIGVQGLEGNLQMPGIKSSGCDVNLPG--------VNVKLPTGQ--I 5518
                           G  G EG +  PG +    D   PG        +  + P G   +
Sbjct: 1973 VPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGL 2032

Query: 5519 SGPEIKGGLKG--------SEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGA 5570
            +G   K G+ G         E G  G   +   KG                 GP    G 
Sbjct: 2033 AGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGP 2092

Query: 5571 DVSGGVSAPDISLGEGHLSVKGSGGE--------WKGPQVSSALNLDTSK---------- 5612
             VS     P +S  +G   +KG+ GE         KG +    +  D  +          
Sbjct: 2093 KVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNP 2152

Query: 5613 -FAGGLHFSGPKVEGGVKG-----GQIGLQ-------APGLS-VSGPQG--HLESGSGKV 5656
               G    +GP+ + G++G     G +G         APGL+  +GPQG   L+   G+ 
Sbjct: 2153 GLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGET 2212

Query: 5657 TFPKMKIPKFTFSGRELVGREMGVDVHFPKAEASIQAGAGD-------------GEWEES 5703
              P          GR L G    V +  P   + +    G              G     
Sbjct: 2213 GPP----------GRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRD 2262

Query: 5704 EVKLKKSKIKMPKFNFSK-------PKGKGGVTGSPEASISGSKGDLKSSKASLGSLEGE 5756
                K      P    S        PKG+ G TG+P  ++ G  G  K  K + G L G+
Sbjct: 2263 GASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPG-AKGEKGAPGGLAGD 2321

Query: 5757 AEAE 5760
               E
Sbjct: 2322 LVGE 2325


>gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo
            sapiens]
          Length = 1691

 Score = 65.9 bits (159), Expect = 1e-09
 Identities = 263/1043 (25%), Positives = 357/1043 (34%), Gaps = 182/1043 (17%)

Query: 4876 GTLKGPEVDLKGPRLD----------FEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLHL 4925
            G+ KG + D   P LD          F G       P L+ P      P    PD ++ L
Sbjct: 165  GSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPP---GPPGPLGPDGNMGL 221

Query: 4926 KAPKIGFSGPKLEGGEVDLKGPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKFGFGAK 4985
                 GF G K   G+V L GP    PS      + ++   G     PK KK     G+K
Sbjct: 222  -----GFQGEKGVKGDVGLPGPAGPPPS------TGELEFMG----FPKGKK-----GSK 261

Query: 4986 SPKADIKSPSLDVTVPEAELNLETPEISVGGKGKKSKFKMPKIH----------MSGPKI 5035
                    P   ++ P     L T     G KG+K +  +P +           + GP  
Sbjct: 262  GEPGPKGFPG--ISGPPGFPGLGT----TGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPG 315

Query: 5036 KAKKQGFDLNVPGGEIDASLKAPDVDVNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEF 5095
            +  K+G  L  PG      ++    D+ + GPD  + +D           G    P ++ 
Sbjct: 316  QQGKKG-TLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKG 374

Query: 5096 DIKSPKFKAEAPLPS-PKLEGELQAPDLELSLPAIHVE-GLDIKAKAPKVKMPDVDISVP 5153
            D      +  + +P  P L G   A   +   P +  + G   +       +P  D    
Sbjct: 375  DEGIQGLRGPSGVPGLPALSGVPGALGPQ-GFPGLKGDQGNPGRTTIGAAGLPGRD---- 429

Query: 5154 KIEGDLKGPKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVP 5213
                 L GP       +P+   E L  K ++   G+   Q   P  N+ LKG  IKGD  
Sbjct: 430  ----GLPGPPGPPGPPSPEFETETLHNK-ESGFPGLRGEQG--PKGNLGLKG--IKGDSG 480

Query: 5214 SVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVK-----MEGGGAEVHAQLPSLEGDLRG 5268
                +G  V   GP  +   P      IG+PG+K        GGA+  A  P L G L  
Sbjct: 481  FCACDG-GVPNTGPPGE-PGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPL-- 536

Query: 5269 PDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPG 5328
                  GP       G  + S    MP   G       +G   +   D  VP +    PG
Sbjct: 537  ------GPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDG-VPGL----PG 585

Query: 5329 L-NLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRG-PSLQGDLAVSGDIKCPKVS 5386
            L  L G GG+   G  G+  PG+    K + G P +   G P L G   + GD    K  
Sbjct: 586  LPGLPGDGGQGFPGEKGL--PGLPGE-KGHPGPPGLPGNGLPGLPGPRGLPGD----KGK 638

Query: 5387 VGAP-DLSLEASEGSIKLPKMKLPQFGIST-PGSDLHVNAKGPQ-------------VSG 5431
             G P    L  S+G I LP +    +G S  PG+      KG +               G
Sbjct: 639  DGLPGQQGLPGSKG-ITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKG 697

Query: 5432 ELKGPGVDVNLKGPRISAPNVDFNLEG----------------PKVKGSLGATGEIKGPT 5475
            E   PG+    + P    P  +  L G                P + GS GATG+I G  
Sbjct: 698  EPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGDIFG-- 755

Query: 5476 VGGGLPG-IGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGF 5534
               G PG  G+QGL G+    G      D  LPG         + G   K GL G +   
Sbjct: 756  AENGAPGEQGLQGLTGHKGFLG------DSGLPG---------LKGVHGKPGLLGPK--- 797

Query: 5535 HGAAPDISVKGPAFNMASPESDFGINLKGP-KIKGGADVSGGVSAPDISLGEGHLSVKGS 5593
             G        G      +P S       GP  IKG + + G    P IS   GH   KG+
Sbjct: 798  -GERGSPGTPGQVGQPGTPGS------SGPYGIKGKSGLPGAPGFPGIS---GHPGKKGT 847

Query: 5594 GGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQAPGL-SVSGPQGHLESG 5652
             G+ KGP  S    +      G     G     G+KG        GL ++SGP+G  E G
Sbjct: 848  RGK-KGPPGS----IVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKG--EKG 900

Query: 5653 S-GKVTFPKMKIPKFTFSGRELVGREMGVDVHFPKAEASIQAGAGDGEWEESEVKLKKSK 5711
            S G V FP +         R L G         P   A      GD       V +   +
Sbjct: 901  SVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGD-RGNPGPVGIPSPR 959

Query: 5712 IKMPKFNFSKPKGKGGVTGSPEASISGSKGDLKSSKASLGSLEGEAEAEASSPKGKFSLF 5771
              M        KG  G  GS      G +GD        G              G   + 
Sbjct: 960  RPMSNLWLKGDKGSQGSAGS--NGFPGPRGD-------KGEAGRPGPPGLPGAPGLPGII 1010

Query: 5772 KSKKPRHRSNSFSDEREFSGPSTPTGTLEFEG--GEVSLEGGKVKGKHGKLKFGTFGGLG 5829
            K    +     F   R   G    +G   F G  GE   +G  ++G  G        GL 
Sbjct: 1011 KGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQG--IRGSPGLPGASGLPGLK 1068

Query: 5830 SKSKGHYEVTGSDDETGKLQGSG 5852
              +    E++GS    G+   SG
Sbjct: 1069 GDNGQTVEISGSPGPKGQPGESG 1091



 Score = 47.0 bits (110), Expect = 6e-04
 Identities = 109/398 (27%), Positives = 140/398 (35%), Gaps = 80/398 (20%)

Query: 298 SGDHGKIKFPTMK-VPKFGVSTGREGQTPKAGLRVSAPEVSVGHKG--GKPGLT-IQAPQ 353
           +G  G + FP     P      G  GQ    G  V AP    G KG  G PGL  I  PQ
Sbjct: 127 NGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQ 186

Query: 354 LEVSVPSA----NIEGLEGKLKGPQITGPSLEGDLGLKGAK-PQGHIGVDASAPQIGGSI 408
                P A       GL+G    P   GP     LG +G K  +G +G+   A       
Sbjct: 187 GAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPA------- 239

Query: 409 TGPSVEVQAPDIDVQGPGSKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVPGVSGD 468
            GP             P S   +  M  PK    G+KGE          G    PG+SG 
Sbjct: 240 -GP-------------PPSTGELEFMGFPK-GKKGSKGE---------PGPKGFPGISGP 275

Query: 469 VSLPEIATGGLEGK--------MKGTKVKTPEMIIQKPKISMQDVDLSLGSPKL------ 514
              P + T G +G+        + G +       +Q P    Q    +LG P L      
Sbjct: 276 PGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPP-GQQGKKGTLGFPGLNGFQGI 334

Query: 515 ---KGDIKVSAPGVQGDVKGPQVALKGSRVDIETPNLEGTLTGPR----LGSPSGKTGTC 567
              KGDI +  P V  D+ G    + G+  D   P L G L G      L  PSG  G  
Sbjct: 335 EGQKGDIGLPGPDVFIDIDG--AVISGNPGDPGVPGLPG-LKGDEGIQGLRGPSGVPGLP 391

Query: 568 RISMSEVDLNVAA-PKVKGGVDVTLPRVEGKVKVPEVD-VRGPKVDVSAPDVEAHGPEWN 625
            +S     L     P +KG          G   +P  D + GP      P      PE+ 
Sbjct: 392 ALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPP-----SPEFE 446

Query: 626 LKMPKMKMPTFSTPGAKGEGPDVHMTLPKGDISISGPK 663
            +    K   F  PG +GE        PKG++ + G K
Sbjct: 447 TETLHNKESGF--PGLRGEQG------PKGNLGLKGIK 476



 Score = 44.7 bits (104), Expect = 0.003
 Identities = 106/401 (26%), Positives = 142/401 (35%), Gaps = 61/401 (15%)

Query: 5156 EGDLKGPKVQ----ANLGAPDINIEGLDAKVKTPSFGISAPQV-SIPDVNVNLKGPKIKG 5210
            E   KG K +     N+G P    +G D KV   S  +  P     P V      P + G
Sbjct: 1089 ESGFKGTKGRDGLIGNIGFP--GNKGEDGKVGV-SGDVGLPGAPGFPGVAGMRGEPGLPG 1145

Query: 5211 DVPSVGLEGP--DVDLQGPEAKIKFPKFSMPKIGIPGVKMEGG-------GAEVHAQLPS 5261
                 G  GP     L GP+    FP       G+PG K   G       G    A LP 
Sbjct: 1146 SSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLN-GLPGTKGTHGTPGPSITGVPGPAGLPG 1204

Query: 5262 LEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPS 5321
             +G+   P + +  P      PG+     +   P + GP          L G    S+PS
Sbjct: 1205 PKGEKGYPGIGIGAPGK----PGLRGQKGDRGFPGLQGP--------AGLPGAPGISLPS 1252

Query: 5322 MKVHAPG----LNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVS 5377
            +    PG      L G  G+   G  G   P   ++ + + G P      P + G     
Sbjct: 1253 LIAGQPGDPGRPGLDGERGRP--GPAGPPGPPGPSSNQGDTGDPGF----PGIPGPKGPK 1306

Query: 5378 GDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKG-PQVSGELKGP 5436
            GD   P  S    +L L+   G         P F + TPG        G P + G+  GP
Sbjct: 1307 GDQGIPGFSGLPGELGLKGMRGE--------PGF-MGTPGKVGPPGDPGFPGMKGKA-GP 1356

Query: 5437 GVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPG 5496
                 L+G     P  +     P   G LG  G    P + G     G  GL+G+  +PG
Sbjct: 1357 RGSSGLQGDPGQTPTAEAVQVPP---GPLGLPGIDGIPGLTGDPGAQGPVGLQGSKGLPG 1413

Query: 5497 IKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGA 5537
            I        LPG     P G +  P +  GL+G   GF GA
Sbjct: 1414 IPGKDGPSGLPG-----PPGALGDPGLP-GLQGPP-GFEGA 1447



 Score = 42.0 bits (97), Expect = 0.018
 Identities = 120/450 (26%), Positives = 167/450 (37%), Gaps = 77/450 (17%)

Query: 5242 GIPGVKMEGG-----GAEVHAQLPSLEGDLRGPDVKLEGPDVSLKG----PGVDLPSVNL 5292
            G PG K   G     G+ V   LP L+G    P +      V LKG    PGV       
Sbjct: 840  GHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGL------VGLKGSPGSPGV------A 887

Query: 5293 SMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGL-NLSGVGGKMQVGGDGVKVPGID 5351
             +P +SGP      KG   KG +        V  PG+  L G+ G   + G    +PG  
Sbjct: 888  GLPALSGP------KGE--KGSVGF------VGFPGIPGLPGIPGTRGLKG----IPG-- 927

Query: 5352 ATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQF 5411
            +T K+    P      P  +GD    G +  P       +L L+  +GS    +      
Sbjct: 928  STGKMG---PSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGS----QGSAGSN 980

Query: 5412 GISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRIS-APNVDFNLEG-PKVKGSLGATG 5469
            G   P  D    A  P   G    PG+   +KG      P     + G P +KGS G TG
Sbjct: 981  GFPGPRGDKG-EAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITG 1039

Query: 5470 EIKGPTVGGGLPGIGVQGLEGNLQMPGIK-SSGCDVNL---PGVNVKLPTGQISGPEIKG 5525
                P   G     G  GL G   +PG+K  +G  V +   PG   +       G + + 
Sbjct: 1040 FPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRD 1099

Query: 5526 GLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGE 5585
            GL G+ +GF G   +    G + ++  P +        P   G A + G    P  S  +
Sbjct: 1100 GLIGN-IGFPGNKGEDGKVGVSGDVGLPGA--------PGFPGVAGMRGEPGLPGSSGHQ 1150

Query: 5586 GHLSVKGSGG--EWKG-PQVSSALNLDTSKFAGGLHFS-GPKVEG-----GVKG--GQIG 5634
            G +   GS G    KG P       L+      G H + GP + G     G+ G  G+ G
Sbjct: 1151 GAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKG 1210

Query: 5635 LQAPGLSVSGPQGHLESGSGKVTFPKMKIP 5664
                G+   G  G L    G   FP ++ P
Sbjct: 1211 YPGIGIGAPGKPG-LRGQKGDRGFPGLQGP 1239



 Score = 39.3 bits (90), Expect = 0.12
 Identities = 67/246 (27%), Positives = 90/246 (36%), Gaps = 38/246 (15%)

Query: 5410 QFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEG-PKVKGSLGAT 5468
            Q  +  PG D +    GP      KG       KG  + AP     ++G P + G  G T
Sbjct: 130  QGAVGFPGPDGYPGLLGPPGLPGQKGS------KGDPVLAPGSFKGMKGDPGLPGLDGIT 183

Query: 5469 GEIKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLK 5528
            G    P   G +   G  GL+G    PG    G D N+             G + + G+K
Sbjct: 184  GPQGAPGFPGAVGPAGPPGLQGPPGPPG--PLGPDGNMG-----------LGFQGEKGVK 230

Query: 5529 GSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGEGHL 5588
            G +VG  G A      G    M  P+       KG K + G     G+S P    G G  
Sbjct: 231  G-DVGLPGPAGPPPSTGELEFMGFPKGK-----KGSKGEPGPKGFPGISGPPGFPGLGTT 284

Query: 5589 SVKGSGGEW--------KGPQVSSALNLDTSKFA--GGLHFSGPKVEGGVKG--GQIGLQ 5636
              KG  GE         +GP  S  +     +    G L F G     G++G  G IGL 
Sbjct: 285  GEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLP 344

Query: 5637 APGLSV 5642
             P + +
Sbjct: 345  GPDVFI 350



 Score = 39.3 bits (90), Expect = 0.12
 Identities = 73/293 (24%), Positives = 112/293 (38%), Gaps = 51/293 (17%)

Query: 202  GKTVIRLPSGSGAASPTGSAVDIRAGAISASGPELQGAGHSKLQVTMPGIKVGGSGV--- 258
            G ++  +P  +G   P G       G  +   P L+G    K     PG++ G +G+   
Sbjct: 1190 GPSITGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRG---QKGDRGFPGLQ-GPAGLPGA 1245

Query: 259  -NVNAKGLDLGGRGGVQVPAVDISSSLGGRAVEV--QGPSLESGDHGKIKFPTMKVPK-- 313
              ++   L  G  G    P +D      G A      GPS   GD G   FP +  PK  
Sbjct: 1246 PGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGP 1305

Query: 314  ---FGVS--TGREGQTPKAGLR-----------VSAP--------EVSVGHKG-----GK 344
                G+   +G  G+    G+R           V  P        +   G +G     G 
Sbjct: 1306 KGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGD 1365

Query: 345  PGLTIQAPQLEVSVPSANIEGLEGKLKGPQITG-PSLEGDLGLKGAKPQGHIGVDASAPQ 403
            PG T  A  ++V      + G++G    P +TG P  +G +GL+G+K  G  G+      
Sbjct: 1366 PGQTPTAEAVQVPPGPLGLPGIDGI---PGLTGDPGAQGPVGLQGSK--GLPGIPGKDGP 1420

Query: 404  IGGSITGPSVEVQAPDI-DVQGPGSKLNVPKMKVPKFSVSGAKGEETGIDVTL 455
             G  + GP   +  P +  +QGP      P  + P F + G  G+   +  TL
Sbjct: 1421 SG--LPGPPGALGDPGLPGLQGPPGFEGAPGQQGP-FGMPGMPGQSMRVGYTL 1470



 Score = 38.5 bits (88), Expect = 0.20
 Identities = 122/501 (24%), Positives = 171/501 (34%), Gaps = 99/501 (19%)

Query: 226  AGAISASGPELQGAGHSKLQVTMPGIKVGGSGVNVNAKGLDLGGRGGVQVPAVDISSSLG 285
            AG  + SGP+  G   S   V  PGI  G  G+         G RG   +P         
Sbjct: 887  AGLPALSGPK--GEKGSVGFVGFPGIP-GLPGIP--------GTRGLKGIPGSTGKMGPS 935

Query: 286  GRAVEVQGPSLESGDHGKIKFPTMKVPKFGV-STGREGQTPKAGLR-VSAPEVSVGHKG- 342
            GRA    G   + G+ G +  P+ + P   +   G +G    AG      P    G  G 
Sbjct: 936  GRA-GTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGR 994

Query: 343  -GKPGLTIQAPQLEVSVPSAN----------IEGLEGKLKGPQITG-PSLEGDLGLKGAK 390
             G PGL   AP L   +   +          I GL G      ITG P + G+ G +G +
Sbjct: 995  PGPPGLP-GAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIR 1053

Query: 391  PQGHIGVDASAPQIGGSITGPSVEVQAPDIDVQGPGSKLNVPKMKVPKFSVSGAKGEETG 450
                +   +  P + G   G +VE+         PG     PK +  +    G KG +  
Sbjct: 1054 GSPGLPGASGLPGLKGD-NGQTVEISG------SPG-----PKGQPGESGFKGTKGRDGL 1101

Query: 451  I-DVTLP--TGEVTVPGVSGDVSLPEI----ATGGLEGK--MKGTK--------VKTPEM 493
            I ++  P   GE    GVSGDV LP         G+ G+  + G+         + +P +
Sbjct: 1102 IGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGL 1161

Query: 494  IIQKPKISMQDVDLSLGSPKLKGDIKVSAPGVQGDVKGPQVALKGSRVDIETPNL----- 548
            I  K       +    G P  KG      P + G V GP   L G + +   P +     
Sbjct: 1162 IGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITG-VPGP-AGLPGPKGEKGYPGIGIGAP 1219

Query: 549  --------EGTLTGPRLGSPSGKTGTCRISMSEVDLNVAAPKVKGGVDVTLPRV------ 594
                    +G    P L  P+G  G   IS+  +         + G+D    R       
Sbjct: 1220 GKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPP 1279

Query: 595  -----------EGKVKVPEV-DVRGPKVDVSAPDVEAHGPEWNLKMPKMKMPTFSTPGAK 642
                        G    P +   +GPK D   P       E  LK  + +     TPG  
Sbjct: 1280 GPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKV 1339

Query: 643  GEGPDVHMTLPKGDISISGPK 663
            G         P GD    G K
Sbjct: 1340 G---------PPGDPGFPGMK 1351



 Score = 37.4 bits (85), Expect = 0.44
 Identities = 73/289 (25%), Positives = 110/289 (38%), Gaps = 46/289 (15%)

Query: 293 GPSLESGDHGKIKFPTMKVPKFGVST----GREGQTPKAGLRVSAPEVS--VGHKGGKPG 346
           G + E G+ G+   P +  P+  + +    G  GQ  K G  +  P ++   G +G K  
Sbjct: 282 GTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGT-LGFPGLNGFQGIEGQKGD 340

Query: 347 LTIQAPQLEVSVPSANIEGLEGKLKGPQITG-PSLEGDLGLKGAK-PQGHIGVDASAPQI 404
           + +  P + + +  A I G  G    P + G P L+GD G++G + P G  G+ A +   
Sbjct: 341 IGLPGPDVFIDIDGAVISGNPGD---PGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVP 397

Query: 405 GGSITGPSVEVQAPDIDVQG-PGSKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVP 463
           G    GP           QG PG K +           +G  G +         G    P
Sbjct: 398 GA--LGP-----------QGFPGLKGDQGNPGRTTIGAAGLPGRD---------GLPGPP 435

Query: 464 GVSGDVSLPEIATGGLEGKMKGTKVKTPEMIIQKPK--ISMQDVDLSLGSPKLKGDIKVS 521
           G  G  S PE  T  L  K  G      E   Q PK  + ++ +    G     G +  +
Sbjct: 436 GPPGPPS-PEFETETLHNKESGFPGLRGE---QGPKGNLGLKGIKGDSGFCACDGGVPNT 491

Query: 522 APGVQGDVKGPQ-----VALKGSRVDIETPNLEGTLTGPRLGSPSGKTG 565
            P  +    GP        LKG+R D  +   +G    P L  P G +G
Sbjct: 492 GPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSG 540


>gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo
            sapiens]
          Length = 1690

 Score = 65.9 bits (159), Expect = 1e-09
 Identities = 263/1043 (25%), Positives = 357/1043 (34%), Gaps = 182/1043 (17%)

Query: 4876 GTLKGPEVDLKGPRLD----------FEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLHL 4925
            G+ KG + D   P LD          F G       P L+ P      P    PD ++ L
Sbjct: 164  GSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPP---GPPGPLGPDGNMGL 220

Query: 4926 KAPKIGFSGPKLEGGEVDLKGPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKFGFGAK 4985
                 GF G K   G+V L GP    PS      + ++   G     PK KK     G+K
Sbjct: 221  -----GFQGEKGVKGDVGLPGPAGPPPS------TGELEFMG----FPKGKK-----GSK 260

Query: 4986 SPKADIKSPSLDVTVPEAELNLETPEISVGGKGKKSKFKMPKIH----------MSGPKI 5035
                    P   ++ P     L T     G KG+K +  +P +           + GP  
Sbjct: 261  GEPGPKGFPG--ISGPPGFPGLGT----TGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPG 314

Query: 5036 KAKKQGFDLNVPGGEIDASLKAPDVDVNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEF 5095
            +  K+G  L  PG      ++    D+ + GPD  + +D           G    P ++ 
Sbjct: 315  QQGKKG-TLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKG 373

Query: 5096 DIKSPKFKAEAPLPS-PKLEGELQAPDLELSLPAIHVE-GLDIKAKAPKVKMPDVDISVP 5153
            D      +  + +P  P L G   A   +   P +  + G   +       +P  D    
Sbjct: 374  DEGIQGLRGPSGVPGLPALSGVPGALGPQ-GFPGLKGDQGNPGRTTIGAAGLPGRD---- 428

Query: 5154 KIEGDLKGPKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVP 5213
                 L GP       +P+   E L  K ++   G+   Q   P  N+ LKG  IKGD  
Sbjct: 429  ----GLPGPPGPPGPPSPEFETETLHNK-ESGFPGLRGEQG--PKGNLGLKG--IKGDSG 479

Query: 5214 SVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVK-----MEGGGAEVHAQLPSLEGDLRG 5268
                +G  V   GP  +   P      IG+PG+K        GGA+  A  P L G L  
Sbjct: 480  FCACDG-GVPNTGPPGE-PGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPL-- 535

Query: 5269 PDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPG 5328
                  GP       G  + S    MP   G       +G   +   D  VP +    PG
Sbjct: 536  ------GPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDG-VPGL----PG 584

Query: 5329 L-NLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRG-PSLQGDLAVSGDIKCPKVS 5386
            L  L G GG+   G  G+  PG+    K + G P +   G P L G   + GD    K  
Sbjct: 585  LPGLPGDGGQGFPGEKGL--PGLPGE-KGHPGPPGLPGNGLPGLPGPRGLPGD----KGK 637

Query: 5387 VGAP-DLSLEASEGSIKLPKMKLPQFGIST-PGSDLHVNAKGPQ-------------VSG 5431
             G P    L  S+G I LP +    +G S  PG+      KG +               G
Sbjct: 638  DGLPGQQGLPGSKG-ITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKG 696

Query: 5432 ELKGPGVDVNLKGPRISAPNVDFNLEG----------------PKVKGSLGATGEIKGPT 5475
            E   PG+    + P    P  +  L G                P + GS GATG+I G  
Sbjct: 697  EPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGDIFG-- 754

Query: 5476 VGGGLPG-IGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGF 5534
               G PG  G+QGL G+    G      D  LPG         + G   K GL G +   
Sbjct: 755  AENGAPGEQGLQGLTGHKGFLG------DSGLPG---------LKGVHGKPGLLGPK--- 796

Query: 5535 HGAAPDISVKGPAFNMASPESDFGINLKGP-KIKGGADVSGGVSAPDISLGEGHLSVKGS 5593
             G        G      +P S       GP  IKG + + G    P IS   GH   KG+
Sbjct: 797  -GERGSPGTPGQVGQPGTPGS------SGPYGIKGKSGLPGAPGFPGIS---GHPGKKGT 846

Query: 5594 GGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQAPGL-SVSGPQGHLESG 5652
             G+ KGP  S    +      G     G     G+KG        GL ++SGP+G  E G
Sbjct: 847  RGK-KGPPGS----IVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKG--EKG 899

Query: 5653 S-GKVTFPKMKIPKFTFSGRELVGREMGVDVHFPKAEASIQAGAGDGEWEESEVKLKKSK 5711
            S G V FP +         R L G         P   A      GD       V +   +
Sbjct: 900  SVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGD-RGNPGPVGIPSPR 958

Query: 5712 IKMPKFNFSKPKGKGGVTGSPEASISGSKGDLKSSKASLGSLEGEAEAEASSPKGKFSLF 5771
              M        KG  G  GS      G +GD        G              G   + 
Sbjct: 959  RPMSNLWLKGDKGSQGSAGS--NGFPGPRGD-------KGEAGRPGPPGLPGAPGLPGII 1009

Query: 5772 KSKKPRHRSNSFSDEREFSGPSTPTGTLEFEG--GEVSLEGGKVKGKHGKLKFGTFGGLG 5829
            K    +     F   R   G    +G   F G  GE   +G  ++G  G        GL 
Sbjct: 1010 KGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQG--IRGSPGLPGASGLPGLK 1067

Query: 5830 SKSKGHYEVTGSDDETGKLQGSG 5852
              +    E++GS    G+   SG
Sbjct: 1068 GDNGQTVEISGSPGPKGQPGESG 1090



 Score = 47.0 bits (110), Expect = 6e-04
 Identities = 109/398 (27%), Positives = 140/398 (35%), Gaps = 80/398 (20%)

Query: 298 SGDHGKIKFPTMK-VPKFGVSTGREGQTPKAGLRVSAPEVSVGHKG--GKPGLT-IQAPQ 353
           +G  G + FP     P      G  GQ    G  V AP    G KG  G PGL  I  PQ
Sbjct: 126 NGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQ 185

Query: 354 LEVSVPSA----NIEGLEGKLKGPQITGPSLEGDLGLKGAK-PQGHIGVDASAPQIGGSI 408
                P A       GL+G    P   GP     LG +G K  +G +G+   A       
Sbjct: 186 GAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPA------- 238

Query: 409 TGPSVEVQAPDIDVQGPGSKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVPGVSGD 468
            GP             P S   +  M  PK    G+KGE          G    PG+SG 
Sbjct: 239 -GP-------------PPSTGELEFMGFPK-GKKGSKGE---------PGPKGFPGISGP 274

Query: 469 VSLPEIATGGLEGK--------MKGTKVKTPEMIIQKPKISMQDVDLSLGSPKL------ 514
              P + T G +G+        + G +       +Q P    Q    +LG P L      
Sbjct: 275 PGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPP-GQQGKKGTLGFPGLNGFQGI 333

Query: 515 ---KGDIKVSAPGVQGDVKGPQVALKGSRVDIETPNLEGTLTGPR----LGSPSGKTGTC 567
              KGDI +  P V  D+ G    + G+  D   P L G L G      L  PSG  G  
Sbjct: 334 EGQKGDIGLPGPDVFIDIDG--AVISGNPGDPGVPGLPG-LKGDEGIQGLRGPSGVPGLP 390

Query: 568 RISMSEVDLNVAA-PKVKGGVDVTLPRVEGKVKVPEVD-VRGPKVDVSAPDVEAHGPEWN 625
            +S     L     P +KG          G   +P  D + GP      P      PE+ 
Sbjct: 391 ALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPP-----SPEFE 445

Query: 626 LKMPKMKMPTFSTPGAKGEGPDVHMTLPKGDISISGPK 663
            +    K   F  PG +GE        PKG++ + G K
Sbjct: 446 TETLHNKESGF--PGLRGEQG------PKGNLGLKGIK 475



 Score = 44.7 bits (104), Expect = 0.003
 Identities = 106/401 (26%), Positives = 142/401 (35%), Gaps = 61/401 (15%)

Query: 5156 EGDLKGPKVQ----ANLGAPDINIEGLDAKVKTPSFGISAPQV-SIPDVNVNLKGPKIKG 5210
            E   KG K +     N+G P    +G D KV   S  +  P     P V      P + G
Sbjct: 1088 ESGFKGTKGRDGLIGNIGFP--GNKGEDGKVGV-SGDVGLPGAPGFPGVAGMRGEPGLPG 1144

Query: 5211 DVPSVGLEGP--DVDLQGPEAKIKFPKFSMPKIGIPGVKMEGG-------GAEVHAQLPS 5261
                 G  GP     L GP+    FP       G+PG K   G       G    A LP 
Sbjct: 1145 SSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLN-GLPGTKGTHGTPGPSITGVPGPAGLPG 1203

Query: 5262 LEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPS 5321
             +G+   P + +  P      PG+     +   P + GP          L G    S+PS
Sbjct: 1204 PKGEKGYPGIGIGAPGK----PGLRGQKGDRGFPGLQGP--------AGLPGAPGISLPS 1251

Query: 5322 MKVHAPG----LNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVS 5377
            +    PG      L G  G+   G  G   P   ++ + + G P      P + G     
Sbjct: 1252 LIAGQPGDPGRPGLDGERGRP--GPAGPPGPPGPSSNQGDTGDPGF----PGIPGPKGPK 1305

Query: 5378 GDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKG-PQVSGELKGP 5436
            GD   P  S    +L L+   G         P F + TPG        G P + G+  GP
Sbjct: 1306 GDQGIPGFSGLPGELGLKGMRGE--------PGF-MGTPGKVGPPGDPGFPGMKGKA-GP 1355

Query: 5437 GVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPG 5496
                 L+G     P  +     P   G LG  G    P + G     G  GL+G+  +PG
Sbjct: 1356 RGSSGLQGDPGQTPTAEAVQVPP---GPLGLPGIDGIPGLTGDPGAQGPVGLQGSKGLPG 1412

Query: 5497 IKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGA 5537
            I        LPG     P G +  P +  GL+G   GF GA
Sbjct: 1413 IPGKDGPSGLPG-----PPGALGDPGLP-GLQGPP-GFEGA 1446



 Score = 42.0 bits (97), Expect = 0.018
 Identities = 120/450 (26%), Positives = 167/450 (37%), Gaps = 77/450 (17%)

Query: 5242 GIPGVKMEGG-----GAEVHAQLPSLEGDLRGPDVKLEGPDVSLKG----PGVDLPSVNL 5292
            G PG K   G     G+ V   LP L+G    P +      V LKG    PGV       
Sbjct: 839  GHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGL------VGLKGSPGSPGV------A 886

Query: 5293 SMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGL-NLSGVGGKMQVGGDGVKVPGID 5351
             +P +SGP      KG   KG +        V  PG+  L G+ G   + G    +PG  
Sbjct: 887  GLPALSGP------KGE--KGSVGF------VGFPGIPGLPGIPGTRGLKG----IPG-- 926

Query: 5352 ATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQF 5411
            +T K+    P      P  +GD    G +  P       +L L+  +GS    +      
Sbjct: 927  STGKMG---PSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGS----QGSAGSN 979

Query: 5412 GISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRIS-APNVDFNLEG-PKVKGSLGATG 5469
            G   P  D    A  P   G    PG+   +KG      P     + G P +KGS G TG
Sbjct: 980  GFPGPRGDKG-EAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITG 1038

Query: 5470 EIKGPTVGGGLPGIGVQGLEGNLQMPGIK-SSGCDVNL---PGVNVKLPTGQISGPEIKG 5525
                P   G     G  GL G   +PG+K  +G  V +   PG   +       G + + 
Sbjct: 1039 FPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRD 1098

Query: 5526 GLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGE 5585
            GL G+ +GF G   +    G + ++  P +        P   G A + G    P  S  +
Sbjct: 1099 GLIGN-IGFPGNKGEDGKVGVSGDVGLPGA--------PGFPGVAGMRGEPGLPGSSGHQ 1149

Query: 5586 GHLSVKGSGG--EWKG-PQVSSALNLDTSKFAGGLHFS-GPKVEG-----GVKG--GQIG 5634
            G +   GS G    KG P       L+      G H + GP + G     G+ G  G+ G
Sbjct: 1150 GAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKG 1209

Query: 5635 LQAPGLSVSGPQGHLESGSGKVTFPKMKIP 5664
                G+   G  G L    G   FP ++ P
Sbjct: 1210 YPGIGIGAPGKPG-LRGQKGDRGFPGLQGP 1238



 Score = 39.3 bits (90), Expect = 0.12
 Identities = 67/246 (27%), Positives = 90/246 (36%), Gaps = 38/246 (15%)

Query: 5410 QFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEG-PKVKGSLGAT 5468
            Q  +  PG D +    GP      KG       KG  + AP     ++G P + G  G T
Sbjct: 129  QGAVGFPGPDGYPGLLGPPGLPGQKGS------KGDPVLAPGSFKGMKGDPGLPGLDGIT 182

Query: 5469 GEIKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLK 5528
            G    P   G +   G  GL+G    PG    G D N+             G + + G+K
Sbjct: 183  GPQGAPGFPGAVGPAGPPGLQGPPGPPG--PLGPDGNMG-----------LGFQGEKGVK 229

Query: 5529 GSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGEGHL 5588
            G +VG  G A      G    M  P+       KG K + G     G+S P    G G  
Sbjct: 230  G-DVGLPGPAGPPPSTGELEFMGFPKGK-----KGSKGEPGPKGFPGISGPPGFPGLGTT 283

Query: 5589 SVKGSGGEW--------KGPQVSSALNLDTSKFA--GGLHFSGPKVEGGVKG--GQIGLQ 5636
              KG  GE         +GP  S  +     +    G L F G     G++G  G IGL 
Sbjct: 284  GEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLP 343

Query: 5637 APGLSV 5642
             P + +
Sbjct: 344  GPDVFI 349



 Score = 39.3 bits (90), Expect = 0.12
 Identities = 73/293 (24%), Positives = 112/293 (38%), Gaps = 51/293 (17%)

Query: 202  GKTVIRLPSGSGAASPTGSAVDIRAGAISASGPELQGAGHSKLQVTMPGIKVGGSGV--- 258
            G ++  +P  +G   P G       G  +   P L+G    K     PG++ G +G+   
Sbjct: 1189 GPSITGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRG---QKGDRGFPGLQ-GPAGLPGA 1244

Query: 259  -NVNAKGLDLGGRGGVQVPAVDISSSLGGRAVEV--QGPSLESGDHGKIKFPTMKVPK-- 313
              ++   L  G  G    P +D      G A      GPS   GD G   FP +  PK  
Sbjct: 1245 PGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGP 1304

Query: 314  ---FGVS--TGREGQTPKAGLR-----------VSAP--------EVSVGHKG-----GK 344
                G+   +G  G+    G+R           V  P        +   G +G     G 
Sbjct: 1305 KGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGD 1364

Query: 345  PGLTIQAPQLEVSVPSANIEGLEGKLKGPQITG-PSLEGDLGLKGAKPQGHIGVDASAPQ 403
            PG T  A  ++V      + G++G    P +TG P  +G +GL+G+K  G  G+      
Sbjct: 1365 PGQTPTAEAVQVPPGPLGLPGIDGI---PGLTGDPGAQGPVGLQGSK--GLPGIPGKDGP 1419

Query: 404  IGGSITGPSVEVQAPDI-DVQGPGSKLNVPKMKVPKFSVSGAKGEETGIDVTL 455
             G  + GP   +  P +  +QGP      P  + P F + G  G+   +  TL
Sbjct: 1420 SG--LPGPPGALGDPGLPGLQGPPGFEGAPGQQGP-FGMPGMPGQSMRVGYTL 1469



 Score = 38.5 bits (88), Expect = 0.20
 Identities = 122/501 (24%), Positives = 171/501 (34%), Gaps = 99/501 (19%)

Query: 226  AGAISASGPELQGAGHSKLQVTMPGIKVGGSGVNVNAKGLDLGGRGGVQVPAVDISSSLG 285
            AG  + SGP+  G   S   V  PGI  G  G+         G RG   +P         
Sbjct: 886  AGLPALSGPK--GEKGSVGFVGFPGIP-GLPGIP--------GTRGLKGIPGSTGKMGPS 934

Query: 286  GRAVEVQGPSLESGDHGKIKFPTMKVPKFGV-STGREGQTPKAGLR-VSAPEVSVGHKG- 342
            GRA    G   + G+ G +  P+ + P   +   G +G    AG      P    G  G 
Sbjct: 935  GRA-GTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGR 993

Query: 343  -GKPGLTIQAPQLEVSVPSAN----------IEGLEGKLKGPQITG-PSLEGDLGLKGAK 390
             G PGL   AP L   +   +          I GL G      ITG P + G+ G +G +
Sbjct: 994  PGPPGLP-GAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIR 1052

Query: 391  PQGHIGVDASAPQIGGSITGPSVEVQAPDIDVQGPGSKLNVPKMKVPKFSVSGAKGEETG 450
                +   +  P + G   G +VE+         PG     PK +  +    G KG +  
Sbjct: 1053 GSPGLPGASGLPGLKGD-NGQTVEISG------SPG-----PKGQPGESGFKGTKGRDGL 1100

Query: 451  I-DVTLP--TGEVTVPGVSGDVSLPEI----ATGGLEGK--MKGTK--------VKTPEM 493
            I ++  P   GE    GVSGDV LP         G+ G+  + G+         + +P +
Sbjct: 1101 IGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGL 1160

Query: 494  IIQKPKISMQDVDLSLGSPKLKGDIKVSAPGVQGDVKGPQVALKGSRVDIETPNL----- 548
            I  K       +    G P  KG      P + G V GP   L G + +   P +     
Sbjct: 1161 IGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITG-VPGP-AGLPGPKGEKGYPGIGIGAP 1218

Query: 549  --------EGTLTGPRLGSPSGKTGTCRISMSEVDLNVAAPKVKGGVDVTLPRV------ 594
                    +G    P L  P+G  G   IS+  +         + G+D    R       
Sbjct: 1219 GKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPP 1278

Query: 595  -----------EGKVKVPEV-DVRGPKVDVSAPDVEAHGPEWNLKMPKMKMPTFSTPGAK 642
                        G    P +   +GPK D   P       E  LK  + +     TPG  
Sbjct: 1279 GPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKV 1338

Query: 643  GEGPDVHMTLPKGDISISGPK 663
            G         P GD    G K
Sbjct: 1339 G---------PPGDPGFPGMK 1350



 Score = 37.4 bits (85), Expect = 0.44
 Identities = 73/289 (25%), Positives = 110/289 (38%), Gaps = 46/289 (15%)

Query: 293 GPSLESGDHGKIKFPTMKVPKFGVST----GREGQTPKAGLRVSAPEVS--VGHKGGKPG 346
           G + E G+ G+   P +  P+  + +    G  GQ  K G  +  P ++   G +G K  
Sbjct: 281 GTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGT-LGFPGLNGFQGIEGQKGD 339

Query: 347 LTIQAPQLEVSVPSANIEGLEGKLKGPQITG-PSLEGDLGLKGAK-PQGHIGVDASAPQI 404
           + +  P + + +  A I G  G    P + G P L+GD G++G + P G  G+ A +   
Sbjct: 340 IGLPGPDVFIDIDGAVISGNPGD---PGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVP 396

Query: 405 GGSITGPSVEVQAPDIDVQG-PGSKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVP 463
           G    GP           QG PG K +           +G  G +         G    P
Sbjct: 397 GA--LGP-----------QGFPGLKGDQGNPGRTTIGAAGLPGRD---------GLPGPP 434

Query: 464 GVSGDVSLPEIATGGLEGKMKGTKVKTPEMIIQKPK--ISMQDVDLSLGSPKLKGDIKVS 521
           G  G  S PE  T  L  K  G      E   Q PK  + ++ +    G     G +  +
Sbjct: 435 GPPGPPS-PEFETETLHNKESGFPGLRGE---QGPKGNLGLKGIKGDSGFCACDGGVPNT 490

Query: 522 APGVQGDVKGPQ-----VALKGSRVDIETPNLEGTLTGPRLGSPSGKTG 565
            P  +    GP        LKG+R D  +   +G    P L  P G +G
Sbjct: 491 GPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSG 539


>gi|154759255 collagen, type XXVIII precursor [Homo sapiens]
          Length = 1125

 Score = 65.5 bits (158), Expect = 2e-09
 Identities = 109/417 (26%), Positives = 156/417 (37%), Gaps = 50/417 (11%)

Query: 5160 KGPK-VQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPSVGLE 5218
            +GP+ V    G P     G   K +  S G + PQ         L+G  IKG+   +G  
Sbjct: 391  RGPEGVPGERGLPGEGFPG--PKGEKGSEGPTGPQ--------GLQGLSIKGEKGDIGPV 440

Query: 5219 GPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGDL--RGPDVKLEGP 5276
            GP   +  P    +  +     IG PG +   G       LP  +G++   GP       
Sbjct: 441  GPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQG-----LPGSKGEVGQMGPTGPRGPV 495

Query: 5277 DVSLKGPGVDLPSVNL-SMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLSGVG 5335
             + ++GP  +  S+ L   P V G D     KG       +A +P  +         G  
Sbjct: 496  GIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKG-------EAGLPGAR------GPEGPP 542

Query: 5336 GKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLE 5395
            GK Q G  G +        +   G P     GP  +G+  + G    P  S+  P    +
Sbjct: 543  GKGQPGPKGDEGKKGSKGNQGQRGLPGP--EGP--KGEPGIMGPFGMPGTSIPGPP-GPK 597

Query: 5396 ASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPR-ISAPNVDF 5454
               G   +P  K  + G+S  G       +GP  +  LKG G    + GPR +  P    
Sbjct: 598  GDRGGPGIPGFK-GEPGLSIRGPKGVQGPRGPVGAPGLKGDGYP-GVPGPRGLPGPPGPM 655

Query: 5455 NLEGPKVKGSLGATGE--IKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPGVNVK 5512
             L G    G  GA GE  ++GP    G  G+G QG +G+    G+             +K
Sbjct: 656  GLRGV---GDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGIK 712

Query: 5513 LPTGQISGPEIKG----GLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPK 5565
               G    P  KG    GL G + G HG   D+  KG    +  P S     L+GPK
Sbjct: 713  GEQGPQGFPGPKGTMGHGLPGQK-GEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPK 768



 Score = 65.1 bits (157), Expect = 2e-09
 Identities = 127/465 (27%), Positives = 173/465 (37%), Gaps = 96/465 (20%)

Query: 5206 PKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGD 5265
            P IKG+    G +G   + Q  EA  + P       GIPG K + G        P ++GD
Sbjct: 259  PGIKGER---GPKGNPGNAQKGEAGERGPG------GIPGYKGDKG-ERGECGKPGIKGD 308

Query: 5266 LRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKG-PSLKGDLDASVPSMKV 5324
               P     GP    KGP          +  ++GP  D   KG    KG+     P    
Sbjct: 309  KGSP-----GP-YGPKGPR--------GIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSP 354

Query: 5325 HAPGLNLSGVGGKM-QVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCP 5383
             APG+   G+ G+  Q G  G   P       + VG P      P  +G   V G+   P
Sbjct: 355  GAPGIGQQGIKGERGQEGRPGAPGP-------IGVGEPGQ----PGPRGPEGVPGERGLP 403

Query: 5384 KVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGV----D 5439
                  P    + SEG      ++    G+S  G    +   GPQ  G +  PG+    +
Sbjct: 404  GEGFPGPK-GEKGSEGPTGPQGLQ----GLSIKGEKGDIGPVGPQ--GPMGIPGIGSQGE 456

Query: 5440 VNLKGPRISAPNVDFNLEGPKVKGSLGATGEI--KGPTVGGGLPGIGVQGLEGNLQMPGI 5497
              ++GP I  P      +GP  +G  G+ GE+   GPT   G  GIGVQG +G    PG 
Sbjct: 457  QGIQGP-IGPPGP----QGPAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGE---PG- 507

Query: 5498 KSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDF 5557
                  + LPG         + G +   G KG E G  GA               PE   
Sbjct: 508  -----SIGLPG------QPGVPGEDGAAGKKG-EAGLPGAR-------------GPEGPP 542

Query: 5558 GINLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGL 5617
            G    GPK   G   S G         +G   + G  G    P +     +  +   G  
Sbjct: 543  GKGQPGPKGDEGKKGSKG--------NQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGP- 593

Query: 5618 HFSGPKVEGGVKGGQIGLQAPGLSVSGPQGHLESGSGKVTFPKMK 5662
               GPK + G  G       PGLS+ GP+G ++   G V  P +K
Sbjct: 594  --PGPKGDRGGPGIPGFKGEPGLSIRGPKG-VQGPRGPVGAPGLK 635



 Score = 48.9 bits (115), Expect = 1e-04
 Identities = 103/385 (26%), Positives = 141/385 (36%), Gaps = 53/385 (13%)

Query: 5459 PKVKGSLGATGEIKGPTVG-------GGLPGI-GVQGLEGNLQMPGIKSSGCDVNLPG-V 5509
            P +KG  G  G       G       GG+PG  G +G  G    PGIK    D   PG  
Sbjct: 259  PGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPGIKG---DKGSPGPY 315

Query: 5510 NVKLPTG--QISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIK 5567
              K P G   I+GP    G KG    F G   +    GP  +  +P    GI  +G K +
Sbjct: 316  GPKGPRGIQGITGPPGDPGPKG----FQGNKGEPGPPGPYGSPGAP----GIGQQGIKGE 367

Query: 5568 GGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGG 5627
             G +   G   P I +GE      G  G  +GP+      +   +   G  F GPK E G
Sbjct: 368  RGQEGRPGAPGP-IGVGE-----PGQPGP-RGPE-----GVPGERGLPGEGFPGPKGEKG 415

Query: 5628 VKG--GQIGLQAPGLSVSGPQGHLESGSGKVTFPKMKIPKFTFSGRELVGREMGVDVHFP 5685
             +G  G  GLQ  GLS+ G +G +     +     M IP     G +  G +  +    P
Sbjct: 416  SEGPTGPQGLQ--GLSIKGEKGDIGPVGPQ---GPMGIPGIGSQGEQ--GIQGPIGPPGP 468

Query: 5686 KAEASIQAGAGDGEWEESEVKLKKSKIKMPKFNFSKPKGKGGVTGSP-EASISGSKGDLK 5744
            +  A        GE  +      +  + +       PKG+ G  G P +  + G  G   
Sbjct: 469  QGPAGQGLPGSKGEVGQMGPTGPRGPVGI---GVQGPKGEPGSIGLPGQPGVPGEDG--A 523

Query: 5745 SSKASLGSLEGEAEAEASSPKGKFSLFKSKKPRHRSNSFSDEREFSGPSTPTGTLEFEGG 5804
            + K     L G    E    KG+    K  + +  S     +R   GP  P G      G
Sbjct: 524  AGKKGEAGLPGARGPEGPPGKGQPGP-KGDEGKKGSKGNQGQRGLPGPEGPKGEPGIM-G 581

Query: 5805 EVSLEGGKVKGKHGKLKFGTFGGLG 5829
               + G  + G  G    G  GG G
Sbjct: 582  PFGMPGTSIPGPPGPK--GDRGGPG 604



 Score = 48.9 bits (115), Expect = 1e-04
 Identities = 105/415 (25%), Positives = 154/415 (37%), Gaps = 71/415 (17%)

Query: 293 GPSLESGDHGKIKFPTMKVPKFGVSTGREGQTPKAGLRVSAPEVSVGHKGGKPGLTIQAP 352
           GP    G  G+   P    P      G EG T   GL+       +  KG K  +    P
Sbjct: 389 GPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQ------GLSIKGEKGDIGPVGP 442

Query: 353 QLEVSVP---SANIEGLEGKLKGPQITGPSLEGDLGLKG-------AKPQGHIGVDASAP 402
           Q  + +P   S   +G++G +  P   GP+ +G  G KG         P+G +G+    P
Sbjct: 443 QGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGP 502

Query: 403 Q-IGGSITGPSVEVQAPDIDVQGPGSKLNVPKMKVPK----FSVSGAKGEETGIDVTLPT 457
           +   GSI  P       +    G   +  +P  + P+        G KG+E         
Sbjct: 503 KGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQ 562

Query: 458 GEVTVPGVSGDVSLPEIATGGLEGKMKGTKVKTPEMIIQKPKISMQDVDLSLGSPKLKGD 517
           G+  +PG  G    P I   G  G M GT +  P      PK          G P  KG+
Sbjct: 563 GQRGLPGPEGPKGEPGIM--GPFG-MPGTSIPGP----PGPKGDRG----GPGIPGFKGE 611

Query: 518 IKVSAPGVQGDVKGPQVALKGSRVDIETPNLEGT----LTGPR-LGSPSGKTGTCRISMS 572
                PG+   ++GP+  ++G R  +  P L+G     + GPR L  P G  G   +  +
Sbjct: 612 -----PGL--SIRGPK-GVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDT 663

Query: 573 EVDLNVAAPKVKGGVDVTLPRVEGKVKVPEVDVRGPKVDVSAPDVEA-HGPEWNLKMPKM 631
                   P V+G    + PR         V  +GPK D     +    GP         
Sbjct: 664 GAK---GEPGVRGPPGPSGPR--------GVGTQGPKGDTGQKGLPGPPGP--------- 703

Query: 632 KMPTFSTPGAKGEGPDVHMTLPKGDI--SISGPK-VNVEAPDVNLEGLGGKLKGP 683
             P + + G KGE        PKG +   + G K  + E  DV  +G  G++  P
Sbjct: 704 --PGYGSQGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEP 756



 Score = 42.0 bits (97), Expect = 0.018
 Identities = 110/476 (23%), Positives = 160/476 (33%), Gaps = 139/476 (29%)

Query: 2248 MPKFSMPGFKGE-------GPE----VDVNLPKADVDVSGPKVDVEVPDVSLEGPEGKLK 2296
            +P    PG KGE       GP+    + +   K D+   GP+  + +P +  +G +G ++
Sbjct: 402  LPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQG-IQ 460

Query: 2297 GPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVDVSAPKLEGELKGPELDVKGPKLDAD 2356
            GP                      +  P  +G      P  +GE+   ++   GP+    
Sbjct: 461  GP----------------------IGPPGPQGPAGQGLPGSKGEV--GQMGPTGPRGPVG 496

Query: 2357 MPEVAVEGPNGKWKTPKFKMPDMHFKAPKISMPDLDLHLKSPKAKGEVDVDVPKLEGDLK 2416
               + V+GP G              +   I +P        P   GE      K E  L 
Sbjct: 497  ---IGVQGPKG--------------EPGSIGLPG------QPGVPGEDGAAGKKGEAGLP 533

Query: 2417 GPHVDVSGPDIDIEGPEGK--LKGPKFKMPDMHFKAPNISMPDVDLNLKGPKIKGDVDVS 2474
            G       P     GP+G    KG K          P           +GPK        
Sbjct: 534  GARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGP-----------EGPK-------G 575

Query: 2475 VPEVEGKLEVPDMNI---RGPKVDVNAPDVQAPDWHLKMPKMKMPKFSMPGFKAEGPEVD 2531
             P + G   +P  +I    GPK D   P +                   PGFK E P + 
Sbjct: 576  EPGIMGPFGMPGTSIPGPPGPKGDRGGPGI-------------------PGFKGE-PGLS 615

Query: 2532 VNLPKADVDISGPKVDIEGPDV------NIEGPEGKLKGPKLKMPEMNIKAPKISMPDFD 2585
            +  PK    + GP+  +  P +       + GP G L GP   M    +          D
Sbjct: 616  IRGPKG---VQGPRGPVGAPGLKGDGYPGVPGPRG-LPGPPGPMGLRGVG---------D 662

Query: 2586 LHLKG-PKVKGDVDVSLPKVEGDLKGPEVDI--KGPKVDINAPDVGVQGPDWHLKMPKVK 2642
               KG P V+G    S P+  G  +GP+ D   KG       P  G QG           
Sbjct: 663  TGAKGEPGVRGPPGPSGPRGVG-TQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFP 721

Query: 2643 MPKFSM----PGFKGEGPDGDVKLPKADIDVSGPKVDIEGP----DVNIEGPEGKL 2690
             PK +M    PG KGE  +      + D+   G K +I  P       ++GP+G L
Sbjct: 722  GPKGTMGHGLPGQKGEHGE------RGDVGKKGDKGEIGEPGSPGKQGLQGPKGDL 771



 Score = 42.0 bits (97), Expect = 0.018
 Identities = 93/390 (23%), Positives = 136/390 (34%), Gaps = 69/390 (17%)

Query: 3499 PKGDINIEGPSMNIEGPDLNVEGPEGGLKGPKF-KMPDMNIKAPKISMPDIDLNLKGPKV 3557
            P G   ++G S+  E  D+   GP+G +  P      +  I+ P          +  P  
Sbjct: 419  PTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGP----------IGPPGP 468

Query: 3558 KGDVDISLPKLEGDLKGPEVDIKGPKVDINAPDVDVHGPDWHLKMPKVKMPKFSMPGFKG 3617
            +G     LP  +G     EV   GP        + V G       PK +     +PG  G
Sbjct: 469  QGPAGQGLPGSKG-----EVGQMGPTGPRGPVGIGVQG-------PKGEPGSIGLPGQPG 516

Query: 3618 EGPEVDVTLPKADIDISGPNVDVDVPDVNIEGP--DAKLKGPKFKMPEMNIKAPKISMPD 3675
               E      K +  + G       P     GP  D   KG K    +  +  P+   P 
Sbjct: 517  VPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPE--GPK 574

Query: 3676 FDLNLKGP-KMKGDVVVSLPKVEGDLKGPEV-DIKGPKVDIDTPDINIEGSEGKFKGPKF 3733
             +  + GP  M G  +   P  +GD  GP +   KG       P ++I G +G  +GP+ 
Sbjct: 575  GEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKG------EPGLSIRGPKG-VQGPRG 627

Query: 3734 KIPEMHLKA---PKISMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPE-------VDIKG 3783
             +    LK    P +  P       GP     V  +  K E  ++GP        V  +G
Sbjct: 628  PVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQG 687

Query: 3784 PKVDI---------NAPDVDVQGPDWHLKMPKVKMPKFSM----PGFKGEGPDVDVNLPK 3830
            PK D            P    QG            PK +M    PG KGE  +      +
Sbjct: 688  PKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGE------R 741

Query: 3831 ADLDVSGPKVDIDVP----DVNIEGPEGKL 3856
             D+   G K +I  P       ++GP+G L
Sbjct: 742  GDVGKKGDKGEIGEPGSPGKQGLQGPKGDL 771



 Score = 41.6 bits (96), Expect = 0.024
 Identities = 101/433 (23%), Positives = 160/433 (36%), Gaps = 80/433 (18%)

Query: 3006 IDVPDVGVQGPDWHLKMPKVK-MPKFSMPGFKGE-------GPD----VDVNLPKADLDV 3053
            I V + G  GP     +P  + +P    PG KGE       GP     + +   K D+  
Sbjct: 380  IGVGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGP 439

Query: 3054 SGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSL 3113
             GP+  + +P +  +G +G ++GP                      +  P  +G     L
Sbjct: 440  VGPQGPMGIPGIGSQGEQG-IQGP----------------------IGPPGPQGPAGQGL 476

Query: 3114 PKVEGDMKVPDVDIKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISMPGFKGEGPEVDVN 3173
            P  +G+  V  +   GP+  +    + VQG       PK +   I +PG  G   E    
Sbjct: 477  PGSKGE--VGQMGPTGPRGPVG---IGVQG-------PKGEPGSIGLPGQPGVPGEDGAA 524

Query: 3174 LPKADLDVSGPKVDVDVPDVNIEGP--DAKLKGPKFKMPEMNIKAPKISMPDLDLNLKGP 3231
              K +  + G +     P     GP  D   KG K    +  +  P+   P  +  + GP
Sbjct: 525  GKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPE--GPKGEPGIMGP 582

Query: 3232 -KMKGEVDVSLANVEGDLKGPAL-DIKG-PKIDVDAPDIDIHGPDAKLKGPKLKMPDMHV 3288
              M G         +GD  GP +   KG P + +  P   + GP   +  P LK  D + 
Sbjct: 583  FGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPK-GVQGPRGPVGAPGLK-GDGYP 640

Query: 3289 NMP---KISMPEIDLNLKG---SKLKGDVDVSGPKLEGDIKAPSLDIKGPEVD-----VS 3337
             +P    +  P   + L+G   +  KG+  V GP   G      +  +GP+ D     + 
Sbjct: 641  GVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGP--PGPSGPRGVGTQGPKGDTGQKGLP 698

Query: 3338 GP-------KLNIEGKSKKSRFKLPKFNFS-GSKVQTPEVDVKGKKPDIDITGPKVDINA 3389
            GP          I+G+     F  PK     G   Q  E    G++ D+   G K +I  
Sbjct: 699  GPPGPPGYGSQGIKGEQGPQGFPGPKGTMGHGLPGQKGE---HGERGDVGKKGDKGEIGE 755

Query: 3390 PDVEVQGKVKGSK 3402
            P    +  ++G K
Sbjct: 756  PGSPGKQGLQGPK 768



 Score = 38.1 bits (87), Expect = 0.26
 Identities = 108/427 (25%), Positives = 154/427 (36%), Gaps = 105/427 (24%)

Query: 1259 MPKFSMPGFKGE-GRE----------VDVNLPKADIDVSGPKVDVEVPDVSLEGPEG--- 1304
            +P    PG KGE G E          + +   K DI   GP+  + +P +  +G +G   
Sbjct: 402  LPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQG 461

Query: 1305 -------------KLKGPKFKMPEMHFKAPKISMPDVDLNLKGPKLKGDVDVSLPEVEGE 1351
                          L G K ++ +M    P+     V + ++GPK +    + LP   G+
Sbjct: 462  PIGPPGPQGPAGQGLPGSKGEVGQMGPTGPR---GPVGIGVQGPKGEPG-SIGLP---GQ 514

Query: 1352 MKVPDVD-IKGPKVDISAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVKLPKAD 1410
              VP  D   G K +   P     GP+          P    PG KG+  +   K  +  
Sbjct: 515  PGVPGEDGAAGKKGEAGLP--GARGPE--------GPPGKGQPGPKGDEGKKGSKGNQGQ 564

Query: 1411 VDVSGPKMDAEVPDVNIEGPDAK--LKGPKFKMPEMSIKPQKISIPDVGLHLKGPKMKGD 1468
              + GP           EGP  +  + GP F MP  SI                P  KGD
Sbjct: 565  RGLPGP-----------EGPKGEPGIMGP-FGMPGTSIPGP-------------PGPKGD 599

Query: 1469 Y-DVTVPKVEGEIKAPDVDIKGPKVDINAPDVEVHGPDWHLKMPKVKMPKF-SMPGFKG- 1525
                 +P  +GE   P + I+GPK         V GP   +  P +K   +  +PG +G 
Sbjct: 600  RGGPGIPGFKGE---PGLSIRGPK--------GVQGPRGPVGAPGLKGDGYPGVPGPRGL 648

Query: 1526 EGPEVDMNL-------PKADLGVSGPKVDIDVPDVNLEAPEGK-----LKGPKFKMPSMN 1573
             GP   M L        K + GV GP        V  + P+G      L GP    P   
Sbjct: 649  PGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPP-GPPGYG 707

Query: 1574 IQTHKISMPDVGLNLKAPKLKTDVDVSLPKVEGDLKGPEIDVKAPKMDVNVGDIDIEGPE 1633
             Q  K      G     P  K  +   LP  +G+  G   DV        +G+    G +
Sbjct: 708  SQGIKGEQGPQGF----PGPKGTMGHGLPGQKGE-HGERGDVGKKGDKGEIGEPGSPGKQ 762

Query: 1634 GKLKGPK 1640
            G L+GPK
Sbjct: 763  G-LQGPK 768



 Score = 37.4 bits (85), Expect = 0.44
 Identities = 85/335 (25%), Positives = 126/335 (37%), Gaps = 80/335 (23%)

Query: 4657 MPKFSMPGFKGE-------GPD----VDVNLPKADIDVSGPKVDVDVPDVN------IEG 4699
            +P    PG KGE       GP     + +   K DI   GP+  + +P +       I+G
Sbjct: 402  LPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQG 461

Query: 4700 PDAK----------LKGPKFKMPEMSIKAPKISMPDIDLNLKGPKVK-GDVDVT-LPKVE 4747
            P             L G K ++ +M    P+     + + ++GPK + G + +   P V 
Sbjct: 462  PIGPPGPQGPAGQGLPGSKGEVGQMGPTGPR---GPVGIGVQGPKGEPGSIGLPGQPGVP 518

Query: 4748 GDL----KGPEADIKGPKVDINTPDVDVHGP--DWHLKMPKVKMPKFSMPGFKGEGPDVD 4801
            G+     K  EA + G +     P     GP  D   K  K    +  +PG +G      
Sbjct: 519  GEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEG------ 572

Query: 4802 VSLPKADIDVSGPKVDVDIPDVNIEGPDAKLKG-------PKFK-MPEINIKAPKISIPD 4853
               PK +  + GP     +P  +I GP    KG       P FK  P ++I+ PK  +  
Sbjct: 573  ---PKGEPGIMGP---FGMPGTSIPGPPGP-KGDRGGPGIPGFKGEPGLSIRGPK-GVQG 624

Query: 4854 VDLDLKGPKVKGDFDVSVPKVEGTLKGPEVDLKGPR-LDFEGPDAKLSGPSLKMPSLEIS 4912
                +  P +KGD    VP   G L GP     GP  L   G       P ++ P     
Sbjct: 625  PRGPVGAPGLKGDGYPGVPGPRG-LPGPP----GPMGLRGVGDTGAKGEPGVRGP----- 674

Query: 4913 APKVTAPDVDLHLKAPKIGFSGPKLEGGEVDLKGP 4947
             P  + P          +G  GPK + G+  L GP
Sbjct: 675  -PGPSGPR--------GVGTQGPKGDTGQKGLPGP 700



 Score = 37.0 bits (84), Expect = 0.58
 Identities = 105/454 (23%), Positives = 161/454 (35%), Gaps = 86/454 (18%)

Query: 378 PSLEGDLGLKGAK-PQGHIGVDASAPQIGGSITGPSVEVQAPDIDVQGPGSKLNVPKMKV 436
           P   G+ G+KG + P+G+ G                   Q  +   +GPG    +P  K 
Sbjct: 253 PGTHGNPGIKGERGPKGNPG-----------------NAQKGEAGERGPGG---IPGYKG 292

Query: 437 PK-----FSVSGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLEGKMKGTKVKTP 491
            K         G KG++       P G   + G++G    P     G +G         P
Sbjct: 293 DKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDP--GPKGFQGNKGEPGPPGP 350

Query: 492 EMIIQKPKISMQDVDLSLGS---PKLKGDIKVSAPGVQGDVKGPQVALKGSRVDIETPNL 548
                 P I  Q +    G    P   G I V  PG  G  +GP+  + G R        
Sbjct: 351 YGSPGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQPGP-RGPE-GVPGER-------- 400

Query: 549 EGTLTGPRLGSPSGKTGTCRISMSEVDLNVAAPKVKGGVDVTLPRVEGKVKVPEVDVRGP 608
              L G     P G+ G+   +  +    ++    KG +    P  +G + +P +  +G 
Sbjct: 401 --GLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGP--QGPMGIPGIGSQGE 456

Query: 609 KVDVSAPDVEAHGPEWNLKMPKMKMPTFSTPGAKGEGPDVHMTLPKGDISISGPKVNVEA 668
           +  +  P +   GP+               PG+KGE   +  T P+G + I       E 
Sbjct: 457 Q-GIQGP-IGPPGPQGPAGQ--------GLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEP 506

Query: 669 PDVNL---------EGLGGKLKG----PDVKLPDMSVKTPKISMPDVDLHVKGTK----V 711
             + L         +G  GK KG    P  + P+      +   P  D   KG+K     
Sbjct: 507 GSIGLPGQPGVPGEDGAAGK-KGEAGLPGARGPEGPPGKGQPG-PKGDEGKKGSKGNQGQ 564

Query: 712 KGEYDVTVPKLEGELKGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSVPGFKAEGPEVDV 771
           +G      PK E  + GP      P   + GP      PK       +PGFK E P + +
Sbjct: 565 RGLPGPEGPKGEPGIMGP---FGMPGTSIPGPPG----PKGDRGGPGIPGFKGE-PGLSI 616

Query: 772 NLPKADVDISGPKIDVTAPDVSIEEPEGKLKGPK 805
             PK    + GP+  V AP +  +   G + GP+
Sbjct: 617 RGPKG---VQGPRGPVGAPGLKGDGYPG-VPGPR 646


>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
          Length = 2812

 Score = 60.8 bits (146), Expect = 4e-08
 Identities = 81/413 (19%), Positives = 139/413 (33%), Gaps = 59/413 (14%)

Query: 2853 VDVTGP-KVEGDLKGPEVDLKGPKVDIDVPDVNVQGPDWHLKMPKMKMPKFSMPGFKAEG 2911
            V  TGP +  G  + P +  K P V I+ P V  + P    + P +   K ++   K   
Sbjct: 548  VSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTI 607

Query: 2912 PEVDVNLP----------------KADVDVSGPKVDVEGPDVNIEGPEGKLKGP------ 2949
            P    N+P                K  +    P +  E P ++ E P    + P      
Sbjct: 608  PSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEE 667

Query: 2950 ---KFKMPEMNIKAPKIPMPDFDLHLKGPKVK-GDVDISLPKVEGDLKGPEVDIRGPQVD 3005
                 + P +  + P IP     +  + P +   +  IS  K     + P +    P + 
Sbjct: 668  TTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIP 727

Query: 3006 IDVPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLP-----KADLDVSGPKVDI 3060
             +   +  + P    + P +   K   P    E P      P     K  +    P +  
Sbjct: 728  TEKSTISPEKPTTPTEKPTIPTEK---PTISPEKPTTPTEKPTISPEKLTIPTEKPTIPT 784

Query: 3061 DVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDM 3120
            + P +  E P    + P     E  I   K S+P     ++ P        +LP  E   
Sbjct: 785  EKPTIPTEKPTISTEEPTTPTEETTISTEKPSIP-----MEKP--------TLPTEETTT 831

Query: 3121 KVPDVDIKGPKVDI--NAPDVDVQGPDWHLKMPKIKMPKISMPGFKGEGP---------E 3169
             V +  I   K+ I    P +  + P    + P I   K+++P  K   P         E
Sbjct: 832  SVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEE 891

Query: 3170 VDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP 3222
              ++  K  +    P +  + P ++ E P    + P     E  I   K+++P
Sbjct: 892  TTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIP 944



 Score = 59.3 bits (142), Expect = 1e-07
 Identities = 79/433 (18%), Positives = 145/433 (33%), Gaps = 58/433 (13%)

Query: 771  VNLPKADVDISGPKIDVTAPDVSIEEPEGKLKGPKFKMPEMNIKVPKISMPDVDLHLKGP 830
            ++  K  V I  P +    P V  E+P    + P     +  I   K +MP         
Sbjct: 565  ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPS-------- 616

Query: 831  NVKGEYDVTMPKVESEIKVPDVELKSAKMDIDVPDVEVQGPDWHLKMPKMKMPKFSMPGF 890
                             + P +  +   +  + P +  + P    + P +   K ++P  
Sbjct: 617  -----------------EKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTE 659

Query: 891  KAEGPEVDVNLPKADVDISGPKVGVEVPDVNIEGPEGKLKGPKFKMPE--MNIKAPKISM 948
            +   P  +         +  P +  E P +  E P    + P   M E  ++ + P IS 
Sbjct: 660  EPTTPTEETT-----TSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISP 714

Query: 949  PDVDLHMKGPKVKGEYDMTVP-KLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKFS 1007
                +  + P +  E     P K     + P +    P +  + P    + P I   K +
Sbjct: 715  EKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLT 774

Query: 1008 MPSLKGEGPEFDVNLSKANVDISAPKVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKM 1067
            +P+             K  +    P + T  P +S E P    +       +      K 
Sbjct: 775  IPT------------EKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKP 822

Query: 1068 SLPDVDLDLKGPKMKGNVDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIP 1127
            +LP  +      +      IS  K+   M+ P +    P +  + P +  +     L IP
Sbjct: 823  TLPTEETTTSVEE----TTISTEKLTIPMEKPTISTEKPTIPTEKPTISPE----KLTIP 874

Query: 1128 KMKMPKFSMPSLKGEGP--EVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKM 1185
              K+   ++P+ K   P  E  ++  K  +    P +  E P +S E P    + P    
Sbjct: 875  TEKL---TIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPT 931

Query: 1186 PEMHFKTPKISMP 1198
             E    T K+++P
Sbjct: 932  EETTISTEKLTIP 944



 Score = 59.3 bits (142), Expect = 1e-07
 Identities = 82/441 (18%), Positives = 149/441 (33%), Gaps = 35/441 (7%)

Query: 1481 KAPDVDIKGPKVDINAPDVEVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDMNLP----- 1535
            K P V I+ P V    P V    P    + P +   K ++P  K   P     +P     
Sbjct: 568  KKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPT 627

Query: 1536 -----------KADLGVSGPKVDIDVPDVNLEAPEGKLKGPKFKMPSMNIQTHKISMPDV 1584
                       K  +    P +  + P V  E P    +     M    I T K S+P  
Sbjct: 628  ILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTE 687

Query: 1585 GLNLKAPKLKTDVDVSLPKVEGDLKGPE---IDVKAPKMDVNVGDIDIEGPEGKLKGPKF 1641
              ++   K    ++ ++   E     PE   I  + P +      I  E P    + P  
Sbjct: 688  KPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTI 747

Query: 1642 KMPEMHFKAPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKVDIDAPDV 1701
               +      K + P     +   K    + +   K     + P +  + P +  + P  
Sbjct: 748  PTEKPTISPEKPTTPTEKPTISPEK----LTIPTEKPTIPTEKPTIPTEKPTISTEEPTT 803

Query: 1702 EVHDPDWHLKMPKMKMPKFSMPGFK--AEGPEVDVNLPKADIDVSGPSVDTDAPDLDIEG 1759
               +     + P + M K ++P  +      E  ++  K  I +  P++ T+ P +  E 
Sbjct: 804  PTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEK 863

Query: 1760 PEGKLKGSKFKMPKLNIKAPKVSMPDVDLNLKGPKLKGEIDASVPELEGDLRGPQVDVKG 1819
            P    +       KL I   K ++P  +  +   KL   I    P +  +   P +  + 
Sbjct: 864  PTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKL--TIPTEKPTISPE--KPTISTEK 919

Query: 1820 PFVEAEVPDVDLECPDAKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGD-ADVSVP 1878
            P +  E P +  E  +  +   K  +P    + P IS   + +  + P +  +   +   
Sbjct: 920  PTIPTEKPTIPTE--ETTISTEKLTIPT---EKPTISPEKLTIPTEKPTISTEKPTIPTE 974

Query: 1879 KLEGDLTGPSVGVEVPDVELE 1899
            KL      P++  E P +  E
Sbjct: 975  KLTIPTEKPTIPTEKPTIPTE 995



 Score = 58.9 bits (141), Expect = 1e-07
 Identities = 80/434 (18%), Positives = 149/434 (34%), Gaps = 35/434 (8%)

Query: 1954 PSVGVEVPDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVDLHLKG-----PKVKGDMD 2008
            P+V +E P V  E P    + P     +    T K ++P    ++       P  K  + 
Sbjct: 570  PTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTIL 629

Query: 2009 VSVPKVEGEMKV-----PDVDIKGPKMDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKA 2063
               P +  E        P +  + P +  + P          ++ P +   K S+P  K 
Sbjct: 630  TEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKP 689

Query: 2064 EGPEVDVNLPKADVVVSG--PKVDVEVPDVSLEGPEGKLKGPKLKMPEMHFKAPKISMPD 2121
              P     +   + ++S   P +  E P +  E P    +   +   +      K ++P 
Sbjct: 690  SIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPT 749

Query: 2122 VDLHLKGPKVKGDVD---VSLPKLEGDLTGPSVDVEVPDVELECPDAKLKGPKFKMPEMH 2178
                +   K     +   +S  KL      P++  E P +  E P    + P     E  
Sbjct: 750  EKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETT 809

Query: 2179 FKTPKISMPDVNLNLKGPKVKGDMD---VSVPKVEGEMKVPDVDIRGPKVDIDAPDVDVH 2235
              T K S+P     L   +    ++   +S  K+   M+ P +    P +  + P +   
Sbjct: 810  ISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPE 869

Query: 2236 GPDWHLKMPKMKMP--KFSMPGFKGEGP--EVDVNLPKADVDVSGPKVDVEVPDVSLEGP 2291
                     K+ +P  K ++P  K   P  E  ++  K  +    P +  E P +S E P
Sbjct: 870  ---------KLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKP 920

Query: 2292 EGKLKGPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVDVSAPKLEGELKGPELDVKGP 2351
                + P     E    T K+++P     +   K+   +    P +  E   P +  +  
Sbjct: 921  TIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKL--TIPTEKPTISTE--KPTIPTEKL 976

Query: 2352 KLDADMPEVAVEGP 2365
             +  + P +  E P
Sbjct: 977  TIPTEKPTIPTEKP 990



 Score = 58.5 bits (140), Expect = 2e-07
 Identities = 77/388 (19%), Positives = 135/388 (34%), Gaps = 22/388 (5%)

Query: 1084 NVDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLK--- 1140
            N  IS  K    ++ P V    P V  + P +  +    S + P +   K +MPS K   
Sbjct: 562  NPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTI 621

Query: 1141 -GEGPEVDVNLP-----KADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKMPEMHFKTPK 1194
              E P +    P     K  +    P +  E P V  E P    +     M E    T K
Sbjct: 622  PSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEK 681

Query: 1195 ISMPDVDLHLKGPKVKGDVD---VSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWH 1251
             S+P     +   K    ++   +S  K     + P +  + P +  +   +  + P   
Sbjct: 682  PSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTP 741

Query: 1252 LKMPKM--KMPKFSMPGFKGEGREVDVNLPKADIDVSGPKVDVEVPDVSLEGPEGKLKGP 1309
             + P +  + P  S         +  ++  K  I    P +  E P +  E P    + P
Sbjct: 742  TEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEP 801

Query: 1310 KFKMPEMHFKAPKISMPDVDLNLKGPKL-KGDVDVSLPEVEGEMKVPDVDIKGPKVDISA 1368
                 E      K S+P     ++ P L   +   S+ E     +   + ++ P +    
Sbjct: 802  TTPTEETTISTEKPSIP-----MEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEK 856

Query: 1369 PDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGP--EVDVKLPKADVDVSGPKMDAEVPDVN 1426
            P +    P    +   +   K ++P  K   P  E  +   K  +    P +  E P ++
Sbjct: 857  PTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTIS 916

Query: 1427 IEGPDAKLKGPKFKMPEMSIKPQKISIP 1454
             E P    + P     E +I  +K++IP
Sbjct: 917  TEKPTIPTEKPTIPTEETTISTEKLTIP 944



 Score = 58.5 bits (140), Expect = 2e-07
 Identities = 78/458 (17%), Positives = 159/458 (34%), Gaps = 53/458 (11%)

Query: 850  PDVELKSAKMDIDVPDVEVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLP--KADVD 907
            P +  K   + I+ P V  + P    + P +   K ++   K   P    N+P  K  + 
Sbjct: 563  PTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIP 622

Query: 908  ISGPKVGVEVPDVNIEGPEGKLKGPKF--KMPEMNIKAPKISMPDVDLHMKGPKVKGEYD 965
               P +  E P +  E P    + P    + P +  + P     +    M+ P +  E  
Sbjct: 623  SEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTE-- 680

Query: 966  MTVPKLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGP--EFDVNLS 1023
                K     + P +    P + M+    + + P I   K ++P+ K   P  +  ++  
Sbjct: 681  ----KPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPE 736

Query: 1024 KANVDISAPKVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKGPKMKG 1083
            K       P + T  P +S E P    + P     ++     K ++P             
Sbjct: 737  KPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIP------------- 783

Query: 1084 NVDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLKGEG 1143
                         + P +    P +  + P    +    S + P + M K ++P+     
Sbjct: 784  ------------TEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPT----- 826

Query: 1144 PEVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDLH 1203
             E   ++ +  +      + +E P +S E P    + P     ++   T K+++P     
Sbjct: 827  EETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIP----- 881

Query: 1204 LKGPKVK-GDVDVSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMPKF 1262
             + P +   +  +S  K+    + P +  + P +  + P +  + P    +   +   K 
Sbjct: 882  TEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKL 941

Query: 1263 SMPGFKGEGREVDVNLPKADIDVSGPKVDVEVPDVSLE 1300
            ++P  K       ++  K  I    P +  E P +  E
Sbjct: 942  TIPTEK-----PTISPEKLTIPTEKPTISTEKPTIPTE 974



 Score = 58.2 bits (139), Expect = 2e-07
 Identities = 78/393 (19%), Positives = 131/393 (33%), Gaps = 51/393 (12%)

Query: 4031 KAPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVNLP----- 4085
            K P V I+ P V  + P V    P    + P +   K ++P  K   P     +P     
Sbjct: 568  KKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPT 627

Query: 4086 ----KADIDVSGPKVDIDTPDIDIHGPEGKLKGP---------KFKMPDLHLKAPKISMP 4132
                K  I    P +  + P I    P    + P           + P +  + P I   
Sbjct: 628  ILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTE 687

Query: 4133 EVDLNLKGPKMK-GDVDVSLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHLKMPKV 4191
            +  +  + P +   +  +S  K     + P +  + P +  +   +  + P    + P +
Sbjct: 688  KPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTI 747

Query: 4192 KMPKFSMPGFKGEGPDVDVNLP-----KADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFK 4246
               K   P    E P      P     K  +    P +  + P +  E P    + P   
Sbjct: 748  PTEK---PTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTP 804

Query: 4247 MPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDI--DAPD 4304
              E  I   K S+P     ++ P        +LP  E      E  I   K+ I  + P 
Sbjct: 805  TEETTISTEKPSIP-----MEKP--------TLPTEETTTSVEETTISTEKLTIPMEKPT 851

Query: 4305 VDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVTLPKADIEISGPKVDI---------D 4355
            +    P    + P +   K ++P  K   P    T+P  +  IS  K+ I         +
Sbjct: 852  ISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPE 911

Query: 4356 APDVSIEGPDAKLKGPKFKMPEMNIKAPKISMP 4388
             P +S E P    + P     E  I   K+++P
Sbjct: 912  KPTISTEKPTIPTEKPTIPTEETTISTEKLTIP 944



 Score = 57.8 bits (138), Expect = 3e-07
 Identities = 82/418 (19%), Positives = 137/418 (32%), Gaps = 29/418 (6%)

Query: 4613 ISLPKVEGDLKGPEVDIRDPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFK----GE 4668
            IS  K    ++ P V    P V  + P +  + P    + P +   K +MP  K     E
Sbjct: 565  ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSE 624

Query: 4669 GPDVDVNLP-----KADIDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMSIKAPKISM 4723
             P +    P     K  I    P +  + P V  E P    +     M E  I   K S+
Sbjct: 625  KPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSI 684

Query: 4724 PDIDLNLKGPKVKGDVDVTLPKVEGDLKGPE---ADIKGPKVDINTPDVDVHGPDWHLKM 4780
            P    ++   K    ++ T+   E     PE      + P +      +    P    + 
Sbjct: 685  PTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEK 744

Query: 4781 PKVKMPKFSMPGFKGEGPDVDVSLP-----KADIDVSGPKVDVDIPDVNIEGPDAKLKGP 4835
            P +   K   P    E P      P     K  I    P +  + P +  E P    + P
Sbjct: 745  PTIPTEK---PTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEP 801

Query: 4836 KFKMPEINIKAPKISIPDVDLDLKGPKV-KGDFDVSVPKVEGTLKGPEVDLKGPRLDFEG 4894
                 E  I   K SIP     ++ P +   +   SV +   + +   + ++ P +  E 
Sbjct: 802  TTPTEETTISTEKPSIP-----MEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEK 856

Query: 4895 PDAKLSGPSLKMPSLEISAPKVTAPDVDLHLKAPKIGFSGPKLEGGEVDLKGPKVEAPSL 4954
            P      P++    L I   K+T P     +   +   S  KL    +  + P +     
Sbjct: 857  PTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKL---TIPTEKPTISPEKP 913

Query: 4955 DVHMDSPDINIEGPDVKIPKFKKPKFGFGAKSPKADIKSPSLDVTVPEAELNLETPEI 5012
             +  + P I  E P +   +           + K  I    L +   +  ++ E P I
Sbjct: 914  TISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTI 971



 Score = 57.4 bits (137), Expect = 4e-07
 Identities = 84/494 (17%), Positives = 168/494 (34%), Gaps = 49/494 (9%)

Query: 2734 GDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKA 2793
            G  + P +  K P V I+ P V    P    + P I   K ++   K   P    N+P  
Sbjct: 558  GLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPS- 616

Query: 2794 DIDVSGPKVDVECPDVNIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDV 2853
                  P +  E P +  E P    + P     +    T K ++P  +   T P  +   
Sbjct: 617  ----EKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEE--PTTPTEETTT 670

Query: 2854 DVTGPKVEGDLKGPEVDLKGPKVDIDVPDVNVQGPDWHLKMPKMKMPKFSMPGFKAEGPE 2913
             +  P +    + P +  + P +  + P ++++      + P +   K ++P    E P 
Sbjct: 671  SMEEPVI--PTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIP---TEKPT 725

Query: 2914 VDVNLPKADVDVSGPKVDVEGPDVNIEGPEGKLKGPKFKMPEMNIKAPKIPMPDFDLHLK 2973
            +     K+ +    P    E P +  E P    + P     +  I   K+ +P       
Sbjct: 726  IPTE--KSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIP------- 776

Query: 2974 GPKVKGDVDISLPKVEGDLKGPEVDIRGPQVDIDVPDVGVQGPDWHLKMPKVKMPKFSMP 3033
                               + P +    P +  + P +  + P    +   +   K S+P
Sbjct: 777  ------------------TEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIP 818

Query: 3034 GFKGEGPDVDVNLPKADLDVSGPKVDI--DVPDVNIEGPEGKLKGPKFKMPEMNIKAPKI 3091
              K   P  +      +  +S  K+ I  + P ++ E P    + P     ++ I   K+
Sbjct: 819  MEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKL 878

Query: 3092 SMPDIDLNLKGPKVK-GDMDVSLPKVEGDMKVPDVDIKGPKVDINAPDVDVQGPDWHLKM 3150
            ++P      + P +   +  +S  K+    + P +  + P +    P +  + P    + 
Sbjct: 879  TIP-----TEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEE 933

Query: 3151 PKIKMPKISMPGFKGEGPEVDVNLP--KADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFK 3208
              I   K+++P  K       + +P  K  +    P +  +   +  E P    + P   
Sbjct: 934  TTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993

Query: 3209 MPEMNIKAPKISMP 3222
              ++    P    P
Sbjct: 994  TEKLTALRPPHPSP 1007



 Score = 57.0 bits (136), Expect = 5e-07
 Identities = 74/408 (18%), Positives = 147/408 (36%), Gaps = 35/408 (8%)

Query: 4620 GDLKGPEVDIRDPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLP-- 4677
            G  + P +  + P V I+ P V  + P    + P +   K ++   K   P    N+P  
Sbjct: 558  GLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSE 617

Query: 4678 KADIDVSGPKVDVDVPDVNIEGPDAKLKGPKF--KMPEMSIKAPKISMPDIDLNLKGPKV 4735
            K  I    P +  + P +  E P    + P    + P +  + P     +   +++ P +
Sbjct: 618  KPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVI 677

Query: 4736 KGDVDVTLPKVEGDLKGPEADIKGPKVDINTPDVDVHGPDWHLKMPKVKMPKFSMPGFKG 4795
              +      K     + P    + P + +    +    P    + P +   K ++P  K 
Sbjct: 678  PTE------KPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKS 731

Query: 4796 EGPDVDVSLPKADIDVSGPKVDVDIPDVNIEGPDAKLKGPKFKMPEINIKAPKISIP--D 4853
                  +S  K       P +  + P ++ E P    + P     ++ I   K +IP   
Sbjct: 732  -----TISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEK 786

Query: 4854 VDLDLKGPKVKGDFDVSVPKVEGTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPSLEISA 4913
              +  + P +  + + + P  E T     +  + P +  E P       +  +    IS 
Sbjct: 787  PTIPTEKPTISTE-EPTTPTEETT-----ISTEKPSIPMEKPTLPTEETTTSVEETTIST 840

Query: 4914 PKVTAPDVDLHLKAPKIGFSGPKLEGGEVDLKGPKVEAPS--LDVHMDSPDINIEGPDVK 4971
             K+T P     ++ P I    P +   +  +   K+  P+  L +  + P I IE   + 
Sbjct: 841  EKLTIP-----MEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTIS 895

Query: 4972 IPKFKKP--KFGFGAKSPKADIKSPSLDV---TVPEAELNLETPEISV 5014
              K   P  K     + P    + P++     T+P  E  + T ++++
Sbjct: 896  TEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTI 943



 Score = 57.0 bits (136), Expect = 5e-07
 Identities = 74/400 (18%), Positives = 137/400 (34%), Gaps = 39/400 (9%)

Query: 3624 VTLPKADIDISGPNVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLNLKGP 3683
            ++  K  + I  P+V  + P V  E P    + P     +  I + K +MP     +  P
Sbjct: 565  ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTI--P 622

Query: 3684 KMKGDVVVSLPKVEGDLKGPEVDIKGPKVDIDTPDINIEGSEGKFKGPKFKIPEMHLKAP 3743
              K  ++   P +  +   P +  + P +  + P +  E      +     + E  +   
Sbjct: 623  SEKPTILTEKPTIPSE--KPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTE 680

Query: 3744 KISMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPE---VDIKGPKVDINAPDVDVQGPDW 3800
            K S+P    ++   K    ++ ++   E     PE   +  + P +      +  + P  
Sbjct: 681  KPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTT 740

Query: 3801 HLKMPKVKMPKFSMPGFKGEGPDVDVNLP-----KADLDVSGPKVDIDVPDVNIEGPEGK 3855
              + P +   K   P    E P      P     K  +    P +  + P +  E P   
Sbjct: 741  PTEKPTIPTEK---PTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTIS 797

Query: 3856 LKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMQVPDLDIKGPKVD 3915
             + P     E  I   K S+P     ++ P        +LP  E    V +  I   K+ 
Sbjct: 798  TEEPTTPTEETTISTEKPSIP-----MEKP--------TLPTEETTTSVEETTISTEKLT 844

Query: 3916 I--NAPDVDVRGPDWHLKMPKIKMPKISMPGFKGEGP---------EVDVNLPKADLDVS 3964
            I    P +    P    + P I   K+++P  K   P         E  ++  K  +   
Sbjct: 845  IPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTE 904

Query: 3965 GPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP 4004
             P +  + P ++ E P    + P     E  I   K+++P
Sbjct: 905  KPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIP 944



 Score = 56.2 bits (134), Expect = 9e-07
 Identities = 95/516 (18%), Positives = 176/516 (34%), Gaps = 74/516 (14%)

Query: 1665 PKVKGDMDVSVPKVEGEMKVPDVDIKGPKVDIDAPDVEVHDPDWHLKMPKMKMPKFSMPG 1724
            P V         +  G  + P +  K P V I+ P V    P     +PK K      P 
Sbjct: 543  PPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKP----TVPKEK------PT 592

Query: 1725 FKAEGPEVDVNLPKADIDVSGPSVDTDAPDLDIEGPEGKLKGSKFKMPKLNIKAPKVSMP 1784
               E P +    P   I    P++ ++ P +  E P         + P +  + P +   
Sbjct: 593  IPTEKPTISTEKP--TIPSEKPNMPSEKPTIPSEKPT-----ILTEKPTIPSEKPTIPSE 645

Query: 1785 DVDLNLKGPKLKGEIDASVPELEGDLRGPQVDVKGPFVEAEVPDVDLECPDAKLKGPKFK 1844
               ++ + P +  E + + P  E         ++ P +  E P +  E P    + P   
Sbjct: 646  KPTISTEKPTVPTE-EPTTPTEE-----TTTSMEEPVIPTEKPSIPTEKPSIPTEKPTIS 699

Query: 1845 MPE--MHFKAPKISMPDVDLHLKGPKVKGD-ADVSVPKLEGDLTGPSVGVEVPDVELECP 1901
            M E  +  + P IS     +  + P +  + + +S  K       P++  E P +  E P
Sbjct: 700  MEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKP 759

Query: 1902 DAKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDVDVSVPKLEGDLTGPSVGVEVP 1961
                + P      +     K ++P     +  P  K  +    P    + T  ++  E P
Sbjct: 760  TTPTEKPTISPEKLTIPTEKPTIPTEKPTI--PTEKPTISTEEPTTPTEET--TISTEKP 815

Query: 1962 DVELECPDAKLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVP 2021
             + +E P    +     + E    T K+++P                         M+ P
Sbjct: 816  SIPMEKPTLPTEETTTSVEETTISTEKLTIP-------------------------MEKP 850

Query: 2022 DVDIKGPKMDIDAPDVDVHGPDWHLKMPKMKMP--KFSMPGFKAEGP--EVDVNLPKADV 2077
             +  + P +  + P +            K+ +P  K ++P  K   P  E  ++  K  +
Sbjct: 851  TISTEKPTIPTEKPTISPE---------KLTIPTEKLTIPTEKPTIPIEETTISTEKLTI 901

Query: 2078 VVSGPKVDVEVPDVSLEGPEGKLKGPKLKMPEMHFKAPKISMPDVDLHLKGPKV-----K 2132
                P +  E P +S E P    + P +   E      K+++P     +   K+     K
Sbjct: 902  PTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEK 961

Query: 2133 GDVDVSLPKLEGD-LTGPSVDVEVPDVELECPDAKL 2167
              +    P +  + LT P+    +P  +   P  KL
Sbjct: 962  PTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKL 997



 Score = 55.8 bits (133), Expect = 1e-06
 Identities = 79/439 (17%), Positives = 144/439 (32%), Gaps = 63/439 (14%)

Query: 2532 VNLPKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPKISMPDFDLHLKGP 2591
            ++  K  V I  P V  E P V  E P    + P +   +  I + K +MP         
Sbjct: 565  ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPS-------- 616

Query: 2592 KVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKMPKVKMPKFSMPGF 2651
                             + P +  + P +    P +  + P    + P +   K ++P  
Sbjct: 617  -----------------EKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTE 659

Query: 2652 KGEGPDGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKLKGPKFKMPE--MNIKAPKISM 2709
            +   P       +    +  P +  E P +  E P    + P   M E  ++ + P IS 
Sbjct: 660  EPTTP-----TEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISP 714

Query: 2710 PDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKI 2769
                +  + P +  +     P      + P    + P +  + P +    P    + P I
Sbjct: 715  EKPTIPTEKPTIPTEKSTISP------EKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTI 768

Query: 2770 KMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGPEGKWKSPKFKMPEMH 2829
               K+++P  K                   P +  E P +  E P    + P     E  
Sbjct: 769  SPEKLTIPTEK-------------------PTIPTEKPTIPTEKPTISTEEPTTPTEETT 809

Query: 2830 FKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPEVDLKGPKVDIDVPDVNVQGPD 2889
              T K S+P     L   +    V+ T    E       + ++ P +  + P +  + P 
Sbjct: 810  ISTEKPSIPMEKPTLPTEETTTSVEETTISTE----KLTIPMEKPTISTEKPTIPTEKPT 865

Query: 2890 WHLKMPKMKMPKFSMPGFKAEGP--EVDVNLPKADVDVSGPKVDVEGPDVNIEGPEGKLK 2947
               +   +   K ++P  K   P  E  ++  K  +    P +  E P ++ E P    +
Sbjct: 866  ISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTE 925

Query: 2948 GPKFKMPEMNIKAPKIPMP 2966
             P     E  I   K+ +P
Sbjct: 926  KPTIPTEETTISTEKLTIP 944



 Score = 55.5 bits (132), Expect = 2e-06
 Identities = 87/434 (20%), Positives = 155/434 (35%), Gaps = 28/434 (6%)

Query: 4149 VSLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFK----GE 4204
            +S  K    ++ P V  + P V  + P +  + P    + P +   K +MP  K     E
Sbjct: 565  ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSE 624

Query: 4205 GPDVDVNLP-----KADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISM 4259
             P +    P     K  +    P +  + P V  E P    +     M E  I   K S+
Sbjct: 625  KPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSI 684

Query: 4260 PDFDLHLKGPKVKGDVDVSLPKVEGDLKGPE---VDIKGPKVDIDAPDVDVHGPDWHLKM 4316
            P     +   K    ++ ++   E     PE   +  + P +  +   +    P    + 
Sbjct: 685  PTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEK 744

Query: 4317 PKVKMPKFSMPGFKGEGPDVDVTL--PKADIEISGPKVDIDAPDVSIEGPDAKLKGPKFK 4374
            P +   K ++   K   P    T+   K  I    P +  + P +  E P    + P   
Sbjct: 745  PTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTP 804

Query: 4375 MPEMNIKAPKISMPDIDFNLKGPKVKGDVD---VSLPKVEGDLKGPEIDIKGPSLDIDTP 4431
              E  I   K S+P     L   +    V+   +S  K+   ++ P I  + P++  + P
Sbjct: 805  TEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKP 864

Query: 4432 DVNIEG---PEGKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGD-VDVSLPKVESD 4487
             ++ E    P  KL  P  K P + I+   IS     +  + P +  +   +S  K    
Sbjct: 865  TISPEKLTIPTEKLTIPTEK-PTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIP 923

Query: 4488 LKGPEVDIEGPEGKLKGPKFKMPDVHFKSPQISMSDIDLNLKGPKIKGDM-DISVPKLEG 4546
             + P +  E  E  +   K  +P    + P IS   + +  + P I  +   I   KL  
Sbjct: 924  TEKPTIPTE--ETTISTEKLTIPT---EKPTISPEKLTIPTEKPTISTEKPTIPTEKLTI 978

Query: 4547 DLKGPKVDVKGPKV 4560
              + P +  + P +
Sbjct: 979  PTEKPTIPTEKPTI 992



 Score = 55.1 bits (131), Expect = 2e-06
 Identities = 75/396 (18%), Positives = 131/396 (33%), Gaps = 58/396 (14%)

Query: 717  VTVPKLEGELKGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSVPGFKAEGPEVDVNLP-- 774
            ++  K    ++ P V  + P V    P    + P +   K ++P  K   P     +P  
Sbjct: 565  ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSE 624

Query: 775  --------------KADVDISGPKIDVTAPDVSIEEPEGKLKGPKFKM------------ 808
                          K  +    P I    P V  EEP    +     M            
Sbjct: 625  KPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSI 684

Query: 809  ----PEMNIKVPKISMPDVDLHLKGPNVKGEYDVTMPKVESEIKVPDVELKSAKMDIDVP 864
                P +  + P ISM +  +  + P +  E     P + +E   P +  + + +  + P
Sbjct: 685  PTEKPSIPTEKPTISMEETIISTEKPTISPE----KPTIPTE--KPTIPTEKSTISPEKP 738

Query: 865  DVEVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVGVEVPDVNIEG 924
                + P    + P +   K + P    E P +     K  +    P +  E P +  E 
Sbjct: 739  TTPTEKPTIPTEKPTISPEKPTTP---TEKPTISPE--KLTIPTEKPTIPTEKPTIPTEK 793

Query: 925  PEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGPKVKGEYDMT--------VPKLEGDLK 976
            P    + P     E  I   K S+P     M+ P +  E   T          KL   ++
Sbjct: 794  PTISTEEPTTPTEETTISTEKPSIP-----MEKPTLPTEETTTSVEETTISTEKLTIPME 848

Query: 977  GPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGP--EFDVNLSKANVDISAPKV 1034
             P +    P +  + P  + +   I   K ++P+ K   P  E  ++  K  +    P +
Sbjct: 849  KPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTI 908

Query: 1035 DTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLP 1070
                P +S E P    + P     E      K+++P
Sbjct: 909  SPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIP 944



 Score = 54.3 bits (129), Expect = 4e-06
 Identities = 85/446 (19%), Positives = 147/446 (32%), Gaps = 62/446 (13%)

Query: 899  VNLPKADVDISGPKVGVEVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGP 958
            ++  K  V I  P V  E P V  E P    + P     +  I + K +MP      + P
Sbjct: 565  ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPS-----EKP 619

Query: 959  KVKGEYDMTVPKLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGPEF 1018
             +  E              P +    P +  + P    + P I   K ++P+ +   P  
Sbjct: 620  TIPSE-------------KPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTE 666

Query: 1019 DVNLSKANVDISAPKVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKG 1078
            +   S     +  P + T  P +  E P    + P   M E      K ++      +  
Sbjct: 667  ETTTS-----MEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTI-- 719

Query: 1079 PKMKGNVDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPS 1138
            P  K  +      I  E   P      P +  + P +  +      + P +   K ++P+
Sbjct: 720  PTEKPTIPTEKSTISPEK--PTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPT 777

Query: 1139 LKGEGPEVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMP 1198
             K                   P +  E P +  E P    + P     E    T K S+P
Sbjct: 778  EK-------------------PTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIP 818

Query: 1199 DVDLHLKGPKVKGDVD---VSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMP 1255
                 L   +    V+   +S  K+   M+ P +  + P +  + P +  +         
Sbjct: 819  MEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPE--------- 869

Query: 1256 KMKMP--KFSMPGFKG--EGREVDVNLPKADIDVSGPKVDVEVPDVSLEGPEGKLKGPKF 1311
            K+ +P  K ++P  K      E  ++  K  I    P +  E P +S E P    + P  
Sbjct: 870  KLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTI 929

Query: 1312 KMPEMHFKAPKISMPDVDLNLKGPKL 1337
               E      K+++P     +   KL
Sbjct: 930  PTEETTISTEKLTIPTEKPTISPEKL 955



 Score = 53.5 bits (127), Expect = 6e-06
 Identities = 78/438 (17%), Positives = 143/438 (32%), Gaps = 67/438 (15%)

Query: 2149 PSVDVEVPDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMDVSVPK 2208
            P+V +E P V  E P    + P     +    T K ++P    N+   K           
Sbjct: 570  PTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEK----------- 618

Query: 2209 VEGEMKVPDVDIRGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKGEGPEVDVNLP 2268
                   P +    P +  + P +    P    + P +   K ++P  +   P  +    
Sbjct: 619  -------PTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETT-- 669

Query: 2269 KADVDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKT--PKISMPDVDFNLKGPKI 2326
                 +  P +  E P +  E P    + P   M E    T  P IS        + P I
Sbjct: 670  ---TSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTI 726

Query: 2327 KGDVDVSAPKLEGELKGPELDVKGPKLDADMPEVAVEGPNGKWKTPKFKMPDMHFKAPKI 2386
              +    +P      + P    + P +  + P ++ E P     TP  K        P I
Sbjct: 727  PTEKSTISP------EKPTTPTEKPTIPTEKPTISPEKPT----TPTEK--------PTI 768

Query: 2387 SMPDLDLHLKSPKAKGEVDVDVPKLEGDLKGPHVDVSGPDIDIEGPEGKLKGPKF--KMP 2444
            S   L +  + P    E              P +    P I  E P    +      + P
Sbjct: 769  SPEKLTIPTEKPTIPTE-------------KPTIPTEKPTISTEEPTTPTEETTISTEKP 815

Query: 2445 DMHFKAPNISMPDVDLNLKGPKIKGDVDVSVPEVEGKLEVPDMNIRGPKVDVNAPDVQAP 2504
             +  + P +   +   +++      +  +S  ++   +E P ++   P +    P +   
Sbjct: 816  SIPMEKPTLPTEETTTSVE------ETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPE 869

Query: 2505 DWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDIEGPDVNIEGPEGKLKG 2564
               +   K+ +P    P    E  E  ++  K  +    P +  E P ++ E P    + 
Sbjct: 870  KLTIPTEKLTIPT-EKPTIPIE--ETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEK 926

Query: 2565 PKLKMPEMNIKAPKISMP 2582
            P +   E  I   K+++P
Sbjct: 927  PTIPTEETTISTEKLTIP 944



 Score = 52.4 bits (124), Expect = 1e-05
 Identities = 72/414 (17%), Positives = 140/414 (33%), Gaps = 57/414 (13%)

Query: 1227 PDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMPKFSMPGFKGEGREVDVNLPKADIDVS 1286
            P +  K P + I+ P V  + P    + P +   K +            ++  K  I   
Sbjct: 563  PTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPT------------ISTEKPTIPSE 610

Query: 1287 GPKVDVEVPDVSLEGPEGKLKGPKF--KMPEMHFKAPKISMPDVDLNLKGPKLKGDVDVS 1344
             P +  E P +  E P    + P    + P +  + P IS     +  + P    +    
Sbjct: 611  KPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTE---- 666

Query: 1345 LPEVEGEMKVPDVDIKGPKVDISAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDV 1404
              E    M+ P +  + P +    P +    P   ++   +   K   P    E P +  
Sbjct: 667  --ETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEK---PTISPEKPTIPT 721

Query: 1405 KLP-----KADVDVSGPKMDAEVPDVNIEGPDAKLKGPKFKMPEMSIKPQKISIPDVGLH 1459
            + P     K+ +    P    E P +  E P    + P     + +I P+K++IP     
Sbjct: 722  EKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIP----- 776

Query: 1460 LKGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKVDINAPDVEVHGPDWHLKMPKVKMPKFS 1519
                        T+P      + P +  + P +    P           + P + M K +
Sbjct: 777  --------TEKPTIP-----TEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPT 823

Query: 1520 MPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPDVNLEAPEGKLKGPKFKMPSMNIQTHKI 1579
            +P       E   ++ +  +      + ++ P ++ E P    + P      + I T K+
Sbjct: 824  LP-----TEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKL 878

Query: 1580 SMPDVGLNLKAPKLK-TDVDVSLPKVEGDLKGPEIDVKAPKMDVNVGDIDIEGP 1632
            ++P      + P +   +  +S  K+    + P I  + P +      I  E P
Sbjct: 879  TIP-----TEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKP 927



 Score = 52.4 bits (124), Expect = 1e-05
 Identities = 89/435 (20%), Positives = 148/435 (34%), Gaps = 39/435 (8%)

Query: 2070 VNLPKADVVVSGPKVDVEVPDVSLEGPEGKLKGPKLKMPEMHFKAPKISMPDVDLHLKGP 2129
            ++  K  V +  P V  E P V  E P    + P +   +    + K +MP     +  P
Sbjct: 565  ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTI--P 622

Query: 2130 KVKGDVDVSLPKLEGD-----LTGPSVDVEVPDVELECPDAKLKGPKFKMPEMHFKTPKI 2184
              K  +    P +  +        P++  E P V  E P    +     M E    T K 
Sbjct: 623  SEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKP 682

Query: 2185 SMPDVNLNLKGPKVKGDMD---VSVPKVEGEMKVPDVDIRGPKVDIDAPDVDVHGPDWHL 2241
            S+P    ++   K    M+   +S  K     + P +    P +  +   +    P    
Sbjct: 683  SIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPT 742

Query: 2242 KMPKMKMPKFSMPGFKGEGPEVDVNLP-----KADVDVSGPKVDVEVPDVSLEGPEGKLK 2296
            + P +   K   P    E P      P     K  +    P +  E P +  E P    +
Sbjct: 743  EKPTIPTEK---PTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTE 799

Query: 2297 GPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVD---VSAPKLEGELKGPELDVKGPKL 2353
             P     E    T K S+P     L   +    V+   +S  KL   ++ P +  + P +
Sbjct: 800  EPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTI 859

Query: 2354 DADMPEVAVEG---PNGKWKTPKFKMPDMHFKAPKISMPDLDLHLKSPKAKGEVDVDVPK 2410
              + P ++ E    P  K   P  K P +  +   IS   L +    P  K  +  + P 
Sbjct: 860  PTEKPTISPEKLTIPTEKLTIPTEK-PTIPIEETTISTEKLTI----PTEKPTISPEKPT 914

Query: 2411 LEGDLKGPHVDVSGPDIDIEGPEGKLKGPKFKMPDMHFKAPNISMPDVDLNLKGPKIKGD 2470
            +    + P +    P I  E  E  +   K  +P    + P IS   + +  + P I  +
Sbjct: 915  I--STEKPTIPTEKPTIPTE--ETTISTEKLTIPT---EKPTISPEKLTIPTEKPTISTE 967

Query: 2471 VDVSVPEVEGKLEVP 2485
                  E   KL +P
Sbjct: 968  KPTIPTE---KLTIP 979



 Score = 52.0 bits (123), Expect = 2e-05
 Identities = 77/493 (15%), Positives = 159/493 (32%), Gaps = 47/493 (9%)

Query: 3772 GDLKGPEVDIKGPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKA 3831
            G  + P +  K P V I  P V  + P    + P +   K ++   K   P    N+P  
Sbjct: 558  GLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPS- 616

Query: 3832 DLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDM 3891
                  P +  + P +  E P    + P     +  I   K ++P  +      +    M
Sbjct: 617  ----EKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSM 672

Query: 3892 DVSLPKVEGDMQVPDLDIKGPKVDINAPDVDVRGPDWHLKMPKIKMPKISMPGFKGEGP- 3950
            +  +   E     P +  + P +    P + +       + P I   K ++P  K   P 
Sbjct: 673  EEPVIPTE----KPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPT 728

Query: 3951 -EVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLH 4009
             +  ++  K       P +  + P ++ E P    + P     ++ I   K ++P     
Sbjct: 729  EKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIP----- 783

Query: 4010 LKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFS 4069
                                 + P +  + P +  + P           + P + M K +
Sbjct: 784  --------------------TEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPT 823

Query: 4070 MPGFKGEGPEVDVNLPKADIDVSGPKVDIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKI 4129
            +P       E   ++ +  I      + ++ P I    P    + P      L +   K+
Sbjct: 824  LP-----TEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKL 878

Query: 4130 SMPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHLKMP 4189
            ++P      K      +  +S  K+    + P +  + P +  + P +  + P    +  
Sbjct: 879  TIP----TEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEET 934

Query: 4190 KVKMPKFSMPGFKGEGPDVDVNLP--KADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKM 4247
             +   K ++P  K       + +P  K  +    P +  +   +  E P    + P    
Sbjct: 935  TISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPT 994

Query: 4248 PEMNIKAPKISMP 4260
             ++    P    P
Sbjct: 995  EKLTALRPPHPSP 1007



 Score = 51.2 bits (121), Expect = 3e-05
 Identities = 94/511 (18%), Positives = 170/511 (33%), Gaps = 58/511 (11%)

Query: 3394 VQGKVKGSKFKMPFLSISS---PKVSMPDVELNLKSPKVKGDLDIAGPNLEGDFKGPKVD 3450
            +QG    S   M F+ I+    P   +P++      P V            G  + P + 
Sbjct: 513  IQGSNTASVVAMGFILINPGTCPVKVLPEL------PPVSPVSSTGPSETTGLTENPTIS 566

Query: 3451 IKAPEVNLNAPDVDVHGPDWNLKMPKMKMPKFSVSGLK------------------AEGP 3492
             K P V++  P V    P    + P +   K ++S  K                  +E P
Sbjct: 567  TKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKP 626

Query: 3493 DVAVDLP-----KGDINIEGPSMNIEGPDLNVEGPEGGLKGPKFKMPDMNIKAPKISMPD 3547
             +  + P     K  I  E P+++ E P +  E P    +     M +  I   K S+P 
Sbjct: 627  TILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPT 686

Query: 3548 IDLNLKGPKVKGDVDISLPKLEGDLKGPE---VDIKGPKVDINAPDVDVHGPDWHLKMPK 3604
               ++   K    ++ ++   E     PE   +  + P +      +    P    + P 
Sbjct: 687  EKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPT 746

Query: 3605 VKMPKFSMPGFKGEGPEVDVTL--PKADIDISGPNVDVDVPDVNIEGPDAKLKGPKFKMP 3662
            +   K ++   K   P    T+   K  I    P +  + P +  E P    + P     
Sbjct: 747  IPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTE 806

Query: 3663 EMNIKAPKISMPDFDLNLKGPKMKGDV---VVSLPKVEGDLKGPEVDIKGPKVDIDTPDI 3719
            E  I   K S+P     L   +    V    +S  K+   ++ P +  + P +  + P I
Sbjct: 807  ETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTI 866

Query: 3720 NIEGSEGKFKGPKFKIPEMHLKAPKISMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPEV 3779
            + E         K  IP   L  P    P I +         +  +S  K+    + P +
Sbjct: 867  SPE---------KLTIPTEKLTIP-TEKPTIPIE--------ETTISTEKLTIPTEKPTI 908

Query: 3780 DIKGPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPK 3839
              + P +    P +  + P    +   +   K ++P  K       + +P     +S  K
Sbjct: 909  SPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEK 968

Query: 3840 VDIDVPDVNIEGPEGKLKGPKFKMPEMNIKA 3870
              I    + I   +  +   K  +P   + A
Sbjct: 969  PTIPTEKLTIPTEKPTIPTEKPTIPTEKLTA 999



 Score = 46.2 bits (108), Expect = 0.001
 Identities = 94/486 (19%), Positives = 178/486 (36%), Gaps = 65/486 (13%)

Query: 239 AGHSK-LQVTMPGIKVGGSGVNVNAKGLDLGGRGGVQV------PAVDISSSLGGRAVE- 290
           +GH + +Q+   GI+ G +  +V A G  L   G   V      P V   SS G      
Sbjct: 500 SGHQQPMQLIFKGIQ-GSNTASVVAMGFILINPGTCPVKVLPELPPVSPVSSTGPSETTG 558

Query: 291 -VQGPSLESGDHGKIKFPTMKVPKFGVSTGREGQTPKAGLRVSAPEVSVGHKGGKPGLTI 349
             + P++ +      K PT+ + K  V+T +    PK    +   + ++  +  KP +  
Sbjct: 559 LTENPTIST------KKPTVSIEKPSVTTEKP-TVPKEKPTIPTEKPTISTE--KPTIPS 609

Query: 350 QAPQLEVSVPSANIEGLEGKLKGPQITG--PSLEGDLGLKGAKPQGHIGVDASAP--QIG 405
           + P +    P+   E      + P I    P++  +      +       + + P  +  
Sbjct: 610 EKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETT 669

Query: 406 GSITGPSVEVQAPDIDVQGPGSKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVPGV 465
            S+  P +  + P I  + P      P + + +  +S  K   +    T+PT + T+P  
Sbjct: 670 TSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTE 729

Query: 466 SGDVSLPEIATGGLEGKMKGTKVKTPEMIIQKPKISMQDVDLSLGSPKLKGDIKVSAPGV 525
              +S PE  T         T  + P +  +KP IS +        P +  + K++ P  
Sbjct: 730 KSTIS-PEKPT---------TPTEKPTIPTEKPTISPEKPTTPTEKPTISPE-KLTIP-- 776

Query: 526 QGDVKGPQVALKGSRVDIETPNLEGTLTGPRLGSPSGKTGTCRISMSEVDLNVAAPKVKG 585
               + P +  +   +  E P +           P+  T    IS  +  + +  P    
Sbjct: 777 ---TEKPTIPTEKPTIPTEKPTIS-------TEEPTTPTEETTISTEKPSIPMEKP---- 822

Query: 586 GVDVTLPRVEGKVKVPEVDVRGPK--VDVSAPDVEAHGPEWNLKMPKMKMPTFSTPGAKG 643
               TLP  E    V E  +   K  + +  P +    P    + P +     + P  K 
Sbjct: 823 ----TLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKL 878

Query: 644 EGPDVHMTLPKGDISIS---------GPKVNVEAPDVNLEGLGGKLKGPDVKLPDMSVKT 694
             P    T+P  + +IS          P ++ E P ++ E      + P +   + ++ T
Sbjct: 879 TIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTIST 938

Query: 695 PKISMP 700
            K+++P
Sbjct: 939 EKLTIP 944



 Score = 45.1 bits (105), Expect = 0.002
 Identities = 83/440 (18%), Positives = 145/440 (32%), Gaps = 63/440 (14%)

Query: 4903 SLKMPSLEISAPKVTAPDVDLHLKAPKIGFSGPKLEGGEVDLKGPKVEAPSLDVHMDSPD 4962
            S K P++ I  P VT     +  + P I    P +   +  +   K   PS     + P 
Sbjct: 566  STKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPS-----EKPT 620

Query: 4963 INIEGPDVKIPKFKKPKFGFGAKSPKADIKSPSLDV---TVPEAELNLETPEISVGGKGK 5019
            I  E P +   K   P     ++ P    + P++     TVP  E    T E +   +  
Sbjct: 621  IPSEKPTILTEKPTIP-----SEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEP 675

Query: 5020 KSKFKMPKIHMSGPKIKAKKQGFDLNVPGGEIDASLKAPDVD-----VNIAGPDAALKVD 5074
                + P I    P I  +K    +     E   S + P +      +    P    +  
Sbjct: 676  VIPTEKPSIPTEKPSIPTEKPTISME----ETIISTEKPTISPEKPTIPTEKPTIPTEKS 731

Query: 5075 VKSPKTKKTMFGKMYFPDVEFDIKSPKFKAEAPLPSPKLEGELQAPDLELSLPAIHVEGL 5134
              SP+   T   K            P    E P  SP      + P      P I  E L
Sbjct: 732  TISPEKPTTPTEK------------PTIPTEKPTISP------EKPTTPTEKPTISPEKL 773

Query: 5135 DIKAKAPKV--KMPDVDISVPKIEGDLKGPKVQANLGAPDINIEGLDAKVKTPSFGISAP 5192
             I  + P +  + P +    P I  +            P    E      + PS  +  P
Sbjct: 774  TIPTEKPTIPTEKPTIPTEKPTISTE-----------EPTTPTEETTISTEKPSIPMEKP 822

Query: 5193 QVSIPDVNVNLKGPKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGG 5252
             +   +   +++   I  +  ++ +E P +  + P    + P  S  K+ IP  K+    
Sbjct: 823  TLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPT 882

Query: 5253 -------AEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGV--DLPSVNLSMPKVSGPDLD 5303
                    E       L      P +  E P +S + P +  + P++      +S   L 
Sbjct: 883  EKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLT 942

Query: 5304 LNLKGPSLKGDLDASVPSMK 5323
            +  + P++  +   ++P+ K
Sbjct: 943  IPTEKPTISPE-KLTIPTEK 961



 Score = 33.9 bits (76), Expect = 4.9
 Identities = 29/152 (19%), Positives = 59/152 (38%), Gaps = 15/152 (9%)

Query: 5183 KTPSFGISAPQVSIPDVNVNLKGPKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIG 5242
            + P+     P VSI   +V  + P +  + P++  E P +  + P    + P     K  
Sbjct: 561  ENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPT 620

Query: 5243 IPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDL 5302
            IP  K       +  + P++  +   P +  E P +S      + P+V    P     + 
Sbjct: 621  IPSEK-----PTILTEKPTIPSE--KPTIPSEKPTIS-----TEKPTVPTEEPTTPTEET 668

Query: 5303 DLNLKGPSL---KGDLDASVPSMKVHAPGLNL 5331
              +++ P +   K  +    PS+    P +++
Sbjct: 669  TTSMEEPVIPTEKPSIPTEKPSIPTEKPTISM 700


>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
          Length = 2721

 Score = 60.8 bits (146), Expect = 4e-08
 Identities = 81/413 (19%), Positives = 139/413 (33%), Gaps = 59/413 (14%)

Query: 2853 VDVTGP-KVEGDLKGPEVDLKGPKVDIDVPDVNVQGPDWHLKMPKMKMPKFSMPGFKAEG 2911
            V  TGP +  G  + P +  K P V I+ P V  + P    + P +   K ++   K   
Sbjct: 548  VSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTI 607

Query: 2912 PEVDVNLP----------------KADVDVSGPKVDVEGPDVNIEGPEGKLKGP------ 2949
            P    N+P                K  +    P +  E P ++ E P    + P      
Sbjct: 608  PSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEE 667

Query: 2950 ---KFKMPEMNIKAPKIPMPDFDLHLKGPKVK-GDVDISLPKVEGDLKGPEVDIRGPQVD 3005
                 + P +  + P IP     +  + P +   +  IS  K     + P +    P + 
Sbjct: 668  TTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIP 727

Query: 3006 IDVPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLP-----KADLDVSGPKVDI 3060
             +   +  + P    + P +   K   P    E P      P     K  +    P +  
Sbjct: 728  TEKSTISPEKPTTPTEKPTIPTEK---PTISPEKPTTPTEKPTISPEKLTIPTEKPTIPT 784

Query: 3061 DVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDM 3120
            + P +  E P    + P     E  I   K S+P     ++ P        +LP  E   
Sbjct: 785  EKPTIPTEKPTISTEEPTTPTEETTISTEKPSIP-----MEKP--------TLPTEETTT 831

Query: 3121 KVPDVDIKGPKVDI--NAPDVDVQGPDWHLKMPKIKMPKISMPGFKGEGP---------E 3169
             V +  I   K+ I    P +  + P    + P I   K+++P  K   P         E
Sbjct: 832  SVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEE 891

Query: 3170 VDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP 3222
              ++  K  +    P +  + P ++ E P    + P     E  I   K+++P
Sbjct: 892  TTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIP 944



 Score = 59.3 bits (142), Expect = 1e-07
 Identities = 79/433 (18%), Positives = 145/433 (33%), Gaps = 58/433 (13%)

Query: 771  VNLPKADVDISGPKIDVTAPDVSIEEPEGKLKGPKFKMPEMNIKVPKISMPDVDLHLKGP 830
            ++  K  V I  P +    P V  E+P    + P     +  I   K +MP         
Sbjct: 565  ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPS-------- 616

Query: 831  NVKGEYDVTMPKVESEIKVPDVELKSAKMDIDVPDVEVQGPDWHLKMPKMKMPKFSMPGF 890
                             + P +  +   +  + P +  + P    + P +   K ++P  
Sbjct: 617  -----------------EKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTE 659

Query: 891  KAEGPEVDVNLPKADVDISGPKVGVEVPDVNIEGPEGKLKGPKFKMPE--MNIKAPKISM 948
            +   P  +         +  P +  E P +  E P    + P   M E  ++ + P IS 
Sbjct: 660  EPTTPTEETT-----TSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISP 714

Query: 949  PDVDLHMKGPKVKGEYDMTVP-KLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKFS 1007
                +  + P +  E     P K     + P +    P +  + P    + P I   K +
Sbjct: 715  EKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLT 774

Query: 1008 MPSLKGEGPEFDVNLSKANVDISAPKVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKM 1067
            +P+             K  +    P + T  P +S E P    +       +      K 
Sbjct: 775  IPT------------EKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKP 822

Query: 1068 SLPDVDLDLKGPKMKGNVDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIP 1127
            +LP  +      +      IS  K+   M+ P +    P +  + P +  +     L IP
Sbjct: 823  TLPTEETTTSVEE----TTISTEKLTIPMEKPTISTEKPTIPTEKPTISPE----KLTIP 874

Query: 1128 KMKMPKFSMPSLKGEGP--EVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKM 1185
              K+   ++P+ K   P  E  ++  K  +    P +  E P +S E P    + P    
Sbjct: 875  TEKL---TIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPT 931

Query: 1186 PEMHFKTPKISMP 1198
             E    T K+++P
Sbjct: 932  EETTISTEKLTIP 944



 Score = 59.3 bits (142), Expect = 1e-07
 Identities = 82/441 (18%), Positives = 149/441 (33%), Gaps = 35/441 (7%)

Query: 1481 KAPDVDIKGPKVDINAPDVEVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDMNLP----- 1535
            K P V I+ P V    P V    P    + P +   K ++P  K   P     +P     
Sbjct: 568  KKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPT 627

Query: 1536 -----------KADLGVSGPKVDIDVPDVNLEAPEGKLKGPKFKMPSMNIQTHKISMPDV 1584
                       K  +    P +  + P V  E P    +     M    I T K S+P  
Sbjct: 628  ILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTE 687

Query: 1585 GLNLKAPKLKTDVDVSLPKVEGDLKGPE---IDVKAPKMDVNVGDIDIEGPEGKLKGPKF 1641
              ++   K    ++ ++   E     PE   I  + P +      I  E P    + P  
Sbjct: 688  KPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTI 747

Query: 1642 KMPEMHFKAPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKVDIDAPDV 1701
               +      K + P     +   K    + +   K     + P +  + P +  + P  
Sbjct: 748  PTEKPTISPEKPTTPTEKPTISPEK----LTIPTEKPTIPTEKPTIPTEKPTISTEEPTT 803

Query: 1702 EVHDPDWHLKMPKMKMPKFSMPGFK--AEGPEVDVNLPKADIDVSGPSVDTDAPDLDIEG 1759
               +     + P + M K ++P  +      E  ++  K  I +  P++ T+ P +  E 
Sbjct: 804  PTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEK 863

Query: 1760 PEGKLKGSKFKMPKLNIKAPKVSMPDVDLNLKGPKLKGEIDASVPELEGDLRGPQVDVKG 1819
            P    +       KL I   K ++P  +  +   KL   I    P +  +   P +  + 
Sbjct: 864  PTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKL--TIPTEKPTISPE--KPTISTEK 919

Query: 1820 PFVEAEVPDVDLECPDAKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGD-ADVSVP 1878
            P +  E P +  E  +  +   K  +P    + P IS   + +  + P +  +   +   
Sbjct: 920  PTIPTEKPTIPTE--ETTISTEKLTIPT---EKPTISPEKLTIPTEKPTISTEKPTIPTE 974

Query: 1879 KLEGDLTGPSVGVEVPDVELE 1899
            KL      P++  E P +  E
Sbjct: 975  KLTIPTEKPTIPTEKPTIPTE 995



 Score = 58.9 bits (141), Expect = 1e-07
 Identities = 80/434 (18%), Positives = 149/434 (34%), Gaps = 35/434 (8%)

Query: 1954 PSVGVEVPDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVDLHLKG-----PKVKGDMD 2008
            P+V +E P V  E P    + P     +    T K ++P    ++       P  K  + 
Sbjct: 570  PTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTIL 629

Query: 2009 VSVPKVEGEMKV-----PDVDIKGPKMDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKA 2063
               P +  E        P +  + P +  + P          ++ P +   K S+P  K 
Sbjct: 630  TEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKP 689

Query: 2064 EGPEVDVNLPKADVVVSG--PKVDVEVPDVSLEGPEGKLKGPKLKMPEMHFKAPKISMPD 2121
              P     +   + ++S   P +  E P +  E P    +   +   +      K ++P 
Sbjct: 690  SIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPT 749

Query: 2122 VDLHLKGPKVKGDVD---VSLPKLEGDLTGPSVDVEVPDVELECPDAKLKGPKFKMPEMH 2178
                +   K     +   +S  KL      P++  E P +  E P    + P     E  
Sbjct: 750  EKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETT 809

Query: 2179 FKTPKISMPDVNLNLKGPKVKGDMD---VSVPKVEGEMKVPDVDIRGPKVDIDAPDVDVH 2235
              T K S+P     L   +    ++   +S  K+   M+ P +    P +  + P +   
Sbjct: 810  ISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPE 869

Query: 2236 GPDWHLKMPKMKMP--KFSMPGFKGEGP--EVDVNLPKADVDVSGPKVDVEVPDVSLEGP 2291
                     K+ +P  K ++P  K   P  E  ++  K  +    P +  E P +S E P
Sbjct: 870  ---------KLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKP 920

Query: 2292 EGKLKGPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVDVSAPKLEGELKGPELDVKGP 2351
                + P     E    T K+++P     +   K+   +    P +  E   P +  +  
Sbjct: 921  TIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKL--TIPTEKPTISTE--KPTIPTEKL 976

Query: 2352 KLDADMPEVAVEGP 2365
             +  + P +  E P
Sbjct: 977  TIPTEKPTIPTEKP 990



 Score = 58.5 bits (140), Expect = 2e-07
 Identities = 77/388 (19%), Positives = 135/388 (34%), Gaps = 22/388 (5%)

Query: 1084 NVDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLK--- 1140
            N  IS  K    ++ P V    P V  + P +  +    S + P +   K +MPS K   
Sbjct: 562  NPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTI 621

Query: 1141 -GEGPEVDVNLP-----KADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKMPEMHFKTPK 1194
              E P +    P     K  +    P +  E P V  E P    +     M E    T K
Sbjct: 622  PSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEK 681

Query: 1195 ISMPDVDLHLKGPKVKGDVD---VSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWH 1251
             S+P     +   K    ++   +S  K     + P +  + P +  +   +  + P   
Sbjct: 682  PSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTP 741

Query: 1252 LKMPKM--KMPKFSMPGFKGEGREVDVNLPKADIDVSGPKVDVEVPDVSLEGPEGKLKGP 1309
             + P +  + P  S         +  ++  K  I    P +  E P +  E P    + P
Sbjct: 742  TEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEP 801

Query: 1310 KFKMPEMHFKAPKISMPDVDLNLKGPKL-KGDVDVSLPEVEGEMKVPDVDIKGPKVDISA 1368
                 E      K S+P     ++ P L   +   S+ E     +   + ++ P +    
Sbjct: 802  TTPTEETTISTEKPSIP-----MEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEK 856

Query: 1369 PDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGP--EVDVKLPKADVDVSGPKMDAEVPDVN 1426
            P +    P    +   +   K ++P  K   P  E  +   K  +    P +  E P ++
Sbjct: 857  PTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTIS 916

Query: 1427 IEGPDAKLKGPKFKMPEMSIKPQKISIP 1454
             E P    + P     E +I  +K++IP
Sbjct: 917  TEKPTIPTEKPTIPTEETTISTEKLTIP 944



 Score = 58.5 bits (140), Expect = 2e-07
 Identities = 78/458 (17%), Positives = 159/458 (34%), Gaps = 53/458 (11%)

Query: 850  PDVELKSAKMDIDVPDVEVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLP--KADVD 907
            P +  K   + I+ P V  + P    + P +   K ++   K   P    N+P  K  + 
Sbjct: 563  PTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIP 622

Query: 908  ISGPKVGVEVPDVNIEGPEGKLKGPKF--KMPEMNIKAPKISMPDVDLHMKGPKVKGEYD 965
               P +  E P +  E P    + P    + P +  + P     +    M+ P +  E  
Sbjct: 623  SEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTE-- 680

Query: 966  MTVPKLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGP--EFDVNLS 1023
                K     + P +    P + M+    + + P I   K ++P+ K   P  +  ++  
Sbjct: 681  ----KPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPE 736

Query: 1024 KANVDISAPKVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKGPKMKG 1083
            K       P + T  P +S E P    + P     ++     K ++P             
Sbjct: 737  KPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIP------------- 783

Query: 1084 NVDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLKGEG 1143
                         + P +    P +  + P    +    S + P + M K ++P+     
Sbjct: 784  ------------TEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPT----- 826

Query: 1144 PEVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDLH 1203
             E   ++ +  +      + +E P +S E P    + P     ++   T K+++P     
Sbjct: 827  EETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIP----- 881

Query: 1204 LKGPKVK-GDVDVSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMPKF 1262
             + P +   +  +S  K+    + P +  + P +  + P +  + P    +   +   K 
Sbjct: 882  TEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKL 941

Query: 1263 SMPGFKGEGREVDVNLPKADIDVSGPKVDVEVPDVSLE 1300
            ++P  K       ++  K  I    P +  E P +  E
Sbjct: 942  TIPTEK-----PTISPEKLTIPTEKPTISTEKPTIPTE 974



 Score = 58.2 bits (139), Expect = 2e-07
 Identities = 78/393 (19%), Positives = 131/393 (33%), Gaps = 51/393 (12%)

Query: 4031 KAPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVNLP----- 4085
            K P V I+ P V  + P V    P    + P +   K ++P  K   P     +P     
Sbjct: 568  KKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPT 627

Query: 4086 ----KADIDVSGPKVDIDTPDIDIHGPEGKLKGP---------KFKMPDLHLKAPKISMP 4132
                K  I    P +  + P I    P    + P           + P +  + P I   
Sbjct: 628  ILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTE 687

Query: 4133 EVDLNLKGPKMK-GDVDVSLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHLKMPKV 4191
            +  +  + P +   +  +S  K     + P +  + P +  +   +  + P    + P +
Sbjct: 688  KPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTI 747

Query: 4192 KMPKFSMPGFKGEGPDVDVNLP-----KADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFK 4246
               K   P    E P      P     K  +    P +  + P +  E P    + P   
Sbjct: 748  PTEK---PTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTP 804

Query: 4247 MPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDI--DAPD 4304
              E  I   K S+P     ++ P        +LP  E      E  I   K+ I  + P 
Sbjct: 805  TEETTISTEKPSIP-----MEKP--------TLPTEETTTSVEETTISTEKLTIPMEKPT 851

Query: 4305 VDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVTLPKADIEISGPKVDI---------D 4355
            +    P    + P +   K ++P  K   P    T+P  +  IS  K+ I         +
Sbjct: 852  ISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPE 911

Query: 4356 APDVSIEGPDAKLKGPKFKMPEMNIKAPKISMP 4388
             P +S E P    + P     E  I   K+++P
Sbjct: 912  KPTISTEKPTIPTEKPTIPTEETTISTEKLTIP 944



 Score = 57.8 bits (138), Expect = 3e-07
 Identities = 82/418 (19%), Positives = 137/418 (32%), Gaps = 29/418 (6%)

Query: 4613 ISLPKVEGDLKGPEVDIRDPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFK----GE 4668
            IS  K    ++ P V    P V  + P +  + P    + P +   K +MP  K     E
Sbjct: 565  ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSE 624

Query: 4669 GPDVDVNLP-----KADIDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMSIKAPKISM 4723
             P +    P     K  I    P +  + P V  E P    +     M E  I   K S+
Sbjct: 625  KPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSI 684

Query: 4724 PDIDLNLKGPKVKGDVDVTLPKVEGDLKGPE---ADIKGPKVDINTPDVDVHGPDWHLKM 4780
            P    ++   K    ++ T+   E     PE      + P +      +    P    + 
Sbjct: 685  PTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEK 744

Query: 4781 PKVKMPKFSMPGFKGEGPDVDVSLP-----KADIDVSGPKVDVDIPDVNIEGPDAKLKGP 4835
            P +   K   P    E P      P     K  I    P +  + P +  E P    + P
Sbjct: 745  PTIPTEK---PTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEP 801

Query: 4836 KFKMPEINIKAPKISIPDVDLDLKGPKV-KGDFDVSVPKVEGTLKGPEVDLKGPRLDFEG 4894
                 E  I   K SIP     ++ P +   +   SV +   + +   + ++ P +  E 
Sbjct: 802  TTPTEETTISTEKPSIP-----MEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEK 856

Query: 4895 PDAKLSGPSLKMPSLEISAPKVTAPDVDLHLKAPKIGFSGPKLEGGEVDLKGPKVEAPSL 4954
            P      P++    L I   K+T P     +   +   S  KL    +  + P +     
Sbjct: 857  PTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKL---TIPTEKPTISPEKP 913

Query: 4955 DVHMDSPDINIEGPDVKIPKFKKPKFGFGAKSPKADIKSPSLDVTVPEAELNLETPEI 5012
             +  + P I  E P +   +           + K  I    L +   +  ++ E P I
Sbjct: 914  TISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTI 971



 Score = 57.4 bits (137), Expect = 4e-07
 Identities = 84/494 (17%), Positives = 168/494 (34%), Gaps = 49/494 (9%)

Query: 2734 GDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKA 2793
            G  + P +  K P V I+ P V    P    + P I   K ++   K   P    N+P  
Sbjct: 558  GLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPS- 616

Query: 2794 DIDVSGPKVDVECPDVNIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDV 2853
                  P +  E P +  E P    + P     +    T K ++P  +   T P  +   
Sbjct: 617  ----EKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEE--PTTPTEETTT 670

Query: 2854 DVTGPKVEGDLKGPEVDLKGPKVDIDVPDVNVQGPDWHLKMPKMKMPKFSMPGFKAEGPE 2913
             +  P +    + P +  + P +  + P ++++      + P +   K ++P    E P 
Sbjct: 671  SMEEPVI--PTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIP---TEKPT 725

Query: 2914 VDVNLPKADVDVSGPKVDVEGPDVNIEGPEGKLKGPKFKMPEMNIKAPKIPMPDFDLHLK 2973
            +     K+ +    P    E P +  E P    + P     +  I   K+ +P       
Sbjct: 726  IPTE--KSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIP------- 776

Query: 2974 GPKVKGDVDISLPKVEGDLKGPEVDIRGPQVDIDVPDVGVQGPDWHLKMPKVKMPKFSMP 3033
                               + P +    P +  + P +  + P    +   +   K S+P
Sbjct: 777  ------------------TEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIP 818

Query: 3034 GFKGEGPDVDVNLPKADLDVSGPKVDI--DVPDVNIEGPEGKLKGPKFKMPEMNIKAPKI 3091
              K   P  +      +  +S  K+ I  + P ++ E P    + P     ++ I   K+
Sbjct: 819  MEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKL 878

Query: 3092 SMPDIDLNLKGPKVK-GDMDVSLPKVEGDMKVPDVDIKGPKVDINAPDVDVQGPDWHLKM 3150
            ++P      + P +   +  +S  K+    + P +  + P +    P +  + P    + 
Sbjct: 879  TIP-----TEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEE 933

Query: 3151 PKIKMPKISMPGFKGEGPEVDVNLP--KADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFK 3208
              I   K+++P  K       + +P  K  +    P +  +   +  E P    + P   
Sbjct: 934  TTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993

Query: 3209 MPEMNIKAPKISMP 3222
              ++    P    P
Sbjct: 994  TEKLTALRPPHPSP 1007



 Score = 57.0 bits (136), Expect = 5e-07
 Identities = 74/408 (18%), Positives = 147/408 (36%), Gaps = 35/408 (8%)

Query: 4620 GDLKGPEVDIRDPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLP-- 4677
            G  + P +  + P V I+ P V  + P    + P +   K ++   K   P    N+P  
Sbjct: 558  GLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSE 617

Query: 4678 KADIDVSGPKVDVDVPDVNIEGPDAKLKGPKF--KMPEMSIKAPKISMPDIDLNLKGPKV 4735
            K  I    P +  + P +  E P    + P    + P +  + P     +   +++ P +
Sbjct: 618  KPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVI 677

Query: 4736 KGDVDVTLPKVEGDLKGPEADIKGPKVDINTPDVDVHGPDWHLKMPKVKMPKFSMPGFKG 4795
              +      K     + P    + P + +    +    P    + P +   K ++P  K 
Sbjct: 678  PTE------KPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKS 731

Query: 4796 EGPDVDVSLPKADIDVSGPKVDVDIPDVNIEGPDAKLKGPKFKMPEINIKAPKISIP--D 4853
                  +S  K       P +  + P ++ E P    + P     ++ I   K +IP   
Sbjct: 732  -----TISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEK 786

Query: 4854 VDLDLKGPKVKGDFDVSVPKVEGTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPSLEISA 4913
              +  + P +  + + + P  E T     +  + P +  E P       +  +    IS 
Sbjct: 787  PTIPTEKPTISTE-EPTTPTEETT-----ISTEKPSIPMEKPTLPTEETTTSVEETTIST 840

Query: 4914 PKVTAPDVDLHLKAPKIGFSGPKLEGGEVDLKGPKVEAPS--LDVHMDSPDINIEGPDVK 4971
             K+T P     ++ P I    P +   +  +   K+  P+  L +  + P I IE   + 
Sbjct: 841  EKLTIP-----MEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTIS 895

Query: 4972 IPKFKKP--KFGFGAKSPKADIKSPSLDV---TVPEAELNLETPEISV 5014
              K   P  K     + P    + P++     T+P  E  + T ++++
Sbjct: 896  TEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTI 943



 Score = 57.0 bits (136), Expect = 5e-07
 Identities = 74/400 (18%), Positives = 137/400 (34%), Gaps = 39/400 (9%)

Query: 3624 VTLPKADIDISGPNVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLNLKGP 3683
            ++  K  + I  P+V  + P V  E P    + P     +  I + K +MP     +  P
Sbjct: 565  ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTI--P 622

Query: 3684 KMKGDVVVSLPKVEGDLKGPEVDIKGPKVDIDTPDINIEGSEGKFKGPKFKIPEMHLKAP 3743
              K  ++   P +  +   P +  + P +  + P +  E      +     + E  +   
Sbjct: 623  SEKPTILTEKPTIPSE--KPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTE 680

Query: 3744 KISMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPE---VDIKGPKVDINAPDVDVQGPDW 3800
            K S+P    ++   K    ++ ++   E     PE   +  + P +      +  + P  
Sbjct: 681  KPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTT 740

Query: 3801 HLKMPKVKMPKFSMPGFKGEGPDVDVNLP-----KADLDVSGPKVDIDVPDVNIEGPEGK 3855
              + P +   K   P    E P      P     K  +    P +  + P +  E P   
Sbjct: 741  PTEKPTIPTEK---PTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTIS 797

Query: 3856 LKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMQVPDLDIKGPKVD 3915
             + P     E  I   K S+P     ++ P        +LP  E    V +  I   K+ 
Sbjct: 798  TEEPTTPTEETTISTEKPSIP-----MEKP--------TLPTEETTTSVEETTISTEKLT 844

Query: 3916 I--NAPDVDVRGPDWHLKMPKIKMPKISMPGFKGEGP---------EVDVNLPKADLDVS 3964
            I    P +    P    + P I   K+++P  K   P         E  ++  K  +   
Sbjct: 845  IPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTE 904

Query: 3965 GPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP 4004
             P +  + P ++ E P    + P     E  I   K+++P
Sbjct: 905  KPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIP 944



 Score = 56.2 bits (134), Expect = 9e-07
 Identities = 95/516 (18%), Positives = 176/516 (34%), Gaps = 74/516 (14%)

Query: 1665 PKVKGDMDVSVPKVEGEMKVPDVDIKGPKVDIDAPDVEVHDPDWHLKMPKMKMPKFSMPG 1724
            P V         +  G  + P +  K P V I+ P V    P     +PK K      P 
Sbjct: 543  PPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKP----TVPKEK------PT 592

Query: 1725 FKAEGPEVDVNLPKADIDVSGPSVDTDAPDLDIEGPEGKLKGSKFKMPKLNIKAPKVSMP 1784
               E P +    P   I    P++ ++ P +  E P         + P +  + P +   
Sbjct: 593  IPTEKPTISTEKP--TIPSEKPNMPSEKPTIPSEKPT-----ILTEKPTIPSEKPTIPSE 645

Query: 1785 DVDLNLKGPKLKGEIDASVPELEGDLRGPQVDVKGPFVEAEVPDVDLECPDAKLKGPKFK 1844
               ++ + P +  E + + P  E         ++ P +  E P +  E P    + P   
Sbjct: 646  KPTISTEKPTVPTE-EPTTPTEE-----TTTSMEEPVIPTEKPSIPTEKPSIPTEKPTIS 699

Query: 1845 MPE--MHFKAPKISMPDVDLHLKGPKVKGD-ADVSVPKLEGDLTGPSVGVEVPDVELECP 1901
            M E  +  + P IS     +  + P +  + + +S  K       P++  E P +  E P
Sbjct: 700  MEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKP 759

Query: 1902 DAKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDVDVSVPKLEGDLTGPSVGVEVP 1961
                + P      +     K ++P     +  P  K  +    P    + T  ++  E P
Sbjct: 760  TTPTEKPTISPEKLTIPTEKPTIPTEKPTI--PTEKPTISTEEPTTPTEET--TISTEKP 815

Query: 1962 DVELECPDAKLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVP 2021
             + +E P    +     + E    T K+++P                         M+ P
Sbjct: 816  SIPMEKPTLPTEETTTSVEETTISTEKLTIP-------------------------MEKP 850

Query: 2022 DVDIKGPKMDIDAPDVDVHGPDWHLKMPKMKMP--KFSMPGFKAEGP--EVDVNLPKADV 2077
             +  + P +  + P +            K+ +P  K ++P  K   P  E  ++  K  +
Sbjct: 851  TISTEKPTIPTEKPTISPE---------KLTIPTEKLTIPTEKPTIPIEETTISTEKLTI 901

Query: 2078 VVSGPKVDVEVPDVSLEGPEGKLKGPKLKMPEMHFKAPKISMPDVDLHLKGPKV-----K 2132
                P +  E P +S E P    + P +   E      K+++P     +   K+     K
Sbjct: 902  PTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEK 961

Query: 2133 GDVDVSLPKLEGD-LTGPSVDVEVPDVELECPDAKL 2167
              +    P +  + LT P+    +P  +   P  KL
Sbjct: 962  PTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKL 997



 Score = 55.8 bits (133), Expect = 1e-06
 Identities = 79/439 (17%), Positives = 144/439 (32%), Gaps = 63/439 (14%)

Query: 2532 VNLPKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPKISMPDFDLHLKGP 2591
            ++  K  V I  P V  E P V  E P    + P +   +  I + K +MP         
Sbjct: 565  ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPS-------- 616

Query: 2592 KVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKMPKVKMPKFSMPGF 2651
                             + P +  + P +    P +  + P    + P +   K ++P  
Sbjct: 617  -----------------EKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTE 659

Query: 2652 KGEGPDGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKLKGPKFKMPE--MNIKAPKISM 2709
            +   P       +    +  P +  E P +  E P    + P   M E  ++ + P IS 
Sbjct: 660  EPTTP-----TEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISP 714

Query: 2710 PDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKI 2769
                +  + P +  +     P      + P    + P +  + P +    P    + P I
Sbjct: 715  EKPTIPTEKPTIPTEKSTISP------EKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTI 768

Query: 2770 KMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGPEGKWKSPKFKMPEMH 2829
               K+++P  K                   P +  E P +  E P    + P     E  
Sbjct: 769  SPEKLTIPTEK-------------------PTIPTEKPTIPTEKPTISTEEPTTPTEETT 809

Query: 2830 FKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPEVDLKGPKVDIDVPDVNVQGPD 2889
              T K S+P     L   +    V+ T    E       + ++ P +  + P +  + P 
Sbjct: 810  ISTEKPSIPMEKPTLPTEETTTSVEETTISTE----KLTIPMEKPTISTEKPTIPTEKPT 865

Query: 2890 WHLKMPKMKMPKFSMPGFKAEGP--EVDVNLPKADVDVSGPKVDVEGPDVNIEGPEGKLK 2947
               +   +   K ++P  K   P  E  ++  K  +    P +  E P ++ E P    +
Sbjct: 866  ISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTE 925

Query: 2948 GPKFKMPEMNIKAPKIPMP 2966
             P     E  I   K+ +P
Sbjct: 926  KPTIPTEETTISTEKLTIP 944



 Score = 55.5 bits (132), Expect = 2e-06
 Identities = 87/434 (20%), Positives = 155/434 (35%), Gaps = 28/434 (6%)

Query: 4149 VSLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFK----GE 4204
            +S  K    ++ P V  + P V  + P +  + P    + P +   K +MP  K     E
Sbjct: 565  ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSE 624

Query: 4205 GPDVDVNLP-----KADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISM 4259
             P +    P     K  +    P +  + P V  E P    +     M E  I   K S+
Sbjct: 625  KPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSI 684

Query: 4260 PDFDLHLKGPKVKGDVDVSLPKVEGDLKGPE---VDIKGPKVDIDAPDVDVHGPDWHLKM 4316
            P     +   K    ++ ++   E     PE   +  + P +  +   +    P    + 
Sbjct: 685  PTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEK 744

Query: 4317 PKVKMPKFSMPGFKGEGPDVDVTL--PKADIEISGPKVDIDAPDVSIEGPDAKLKGPKFK 4374
            P +   K ++   K   P    T+   K  I    P +  + P +  E P    + P   
Sbjct: 745  PTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTP 804

Query: 4375 MPEMNIKAPKISMPDIDFNLKGPKVKGDVD---VSLPKVEGDLKGPEIDIKGPSLDIDTP 4431
              E  I   K S+P     L   +    V+   +S  K+   ++ P I  + P++  + P
Sbjct: 805  TEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKP 864

Query: 4432 DVNIEG---PEGKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGD-VDVSLPKVESD 4487
             ++ E    P  KL  P  K P + I+   IS     +  + P +  +   +S  K    
Sbjct: 865  TISPEKLTIPTEKLTIPTEK-PTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIP 923

Query: 4488 LKGPEVDIEGPEGKLKGPKFKMPDVHFKSPQISMSDIDLNLKGPKIKGDM-DISVPKLEG 4546
             + P +  E  E  +   K  +P    + P IS   + +  + P I  +   I   KL  
Sbjct: 924  TEKPTIPTE--ETTISTEKLTIPT---EKPTISPEKLTIPTEKPTISTEKPTIPTEKLTI 978

Query: 4547 DLKGPKVDVKGPKV 4560
              + P +  + P +
Sbjct: 979  PTEKPTIPTEKPTI 992



 Score = 55.1 bits (131), Expect = 2e-06
 Identities = 75/396 (18%), Positives = 131/396 (33%), Gaps = 58/396 (14%)

Query: 717  VTVPKLEGELKGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSVPGFKAEGPEVDVNLP-- 774
            ++  K    ++ P V  + P V    P    + P +   K ++P  K   P     +P  
Sbjct: 565  ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSE 624

Query: 775  --------------KADVDISGPKIDVTAPDVSIEEPEGKLKGPKFKM------------ 808
                          K  +    P I    P V  EEP    +     M            
Sbjct: 625  KPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSI 684

Query: 809  ----PEMNIKVPKISMPDVDLHLKGPNVKGEYDVTMPKVESEIKVPDVELKSAKMDIDVP 864
                P +  + P ISM +  +  + P +  E     P + +E   P +  + + +  + P
Sbjct: 685  PTEKPSIPTEKPTISMEETIISTEKPTISPE----KPTIPTE--KPTIPTEKSTISPEKP 738

Query: 865  DVEVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVGVEVPDVNIEG 924
                + P    + P +   K + P    E P +     K  +    P +  E P +  E 
Sbjct: 739  TTPTEKPTIPTEKPTISPEKPTTP---TEKPTISPE--KLTIPTEKPTIPTEKPTIPTEK 793

Query: 925  PEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGPKVKGEYDMT--------VPKLEGDLK 976
            P    + P     E  I   K S+P     M+ P +  E   T          KL   ++
Sbjct: 794  PTISTEEPTTPTEETTISTEKPSIP-----MEKPTLPTEETTTSVEETTISTEKLTIPME 848

Query: 977  GPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGP--EFDVNLSKANVDISAPKV 1034
             P +    P +  + P  + +   I   K ++P+ K   P  E  ++  K  +    P +
Sbjct: 849  KPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTI 908

Query: 1035 DTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLP 1070
                P +S E P    + P     E      K+++P
Sbjct: 909  SPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIP 944



 Score = 54.3 bits (129), Expect = 4e-06
 Identities = 85/446 (19%), Positives = 147/446 (32%), Gaps = 62/446 (13%)

Query: 899  VNLPKADVDISGPKVGVEVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGP 958
            ++  K  V I  P V  E P V  E P    + P     +  I + K +MP      + P
Sbjct: 565  ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPS-----EKP 619

Query: 959  KVKGEYDMTVPKLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGPEF 1018
             +  E              P +    P +  + P    + P I   K ++P+ +   P  
Sbjct: 620  TIPSE-------------KPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTE 666

Query: 1019 DVNLSKANVDISAPKVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKG 1078
            +   S     +  P + T  P +  E P    + P   M E      K ++      +  
Sbjct: 667  ETTTS-----MEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTI-- 719

Query: 1079 PKMKGNVDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPS 1138
            P  K  +      I  E   P      P +  + P +  +      + P +   K ++P+
Sbjct: 720  PTEKPTIPTEKSTISPEK--PTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPT 777

Query: 1139 LKGEGPEVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMP 1198
             K                   P +  E P +  E P    + P     E    T K S+P
Sbjct: 778  EK-------------------PTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIP 818

Query: 1199 DVDLHLKGPKVKGDVD---VSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMP 1255
                 L   +    V+   +S  K+   M+ P +  + P +  + P +  +         
Sbjct: 819  MEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPE--------- 869

Query: 1256 KMKMP--KFSMPGFKG--EGREVDVNLPKADIDVSGPKVDVEVPDVSLEGPEGKLKGPKF 1311
            K+ +P  K ++P  K      E  ++  K  I    P +  E P +S E P    + P  
Sbjct: 870  KLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTI 929

Query: 1312 KMPEMHFKAPKISMPDVDLNLKGPKL 1337
               E      K+++P     +   KL
Sbjct: 930  PTEETTISTEKLTIPTEKPTISPEKL 955



 Score = 53.5 bits (127), Expect = 6e-06
 Identities = 78/438 (17%), Positives = 143/438 (32%), Gaps = 67/438 (15%)

Query: 2149 PSVDVEVPDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMDVSVPK 2208
            P+V +E P V  E P    + P     +    T K ++P    N+   K           
Sbjct: 570  PTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEK----------- 618

Query: 2209 VEGEMKVPDVDIRGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKGEGPEVDVNLP 2268
                   P +    P +  + P +    P    + P +   K ++P  +   P  +    
Sbjct: 619  -------PTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETT-- 669

Query: 2269 KADVDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKT--PKISMPDVDFNLKGPKI 2326
                 +  P +  E P +  E P    + P   M E    T  P IS        + P I
Sbjct: 670  ---TSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTI 726

Query: 2327 KGDVDVSAPKLEGELKGPELDVKGPKLDADMPEVAVEGPNGKWKTPKFKMPDMHFKAPKI 2386
              +    +P      + P    + P +  + P ++ E P     TP  K        P I
Sbjct: 727  PTEKSTISP------EKPTTPTEKPTIPTEKPTISPEKPT----TPTEK--------PTI 768

Query: 2387 SMPDLDLHLKSPKAKGEVDVDVPKLEGDLKGPHVDVSGPDIDIEGPEGKLKGPKF--KMP 2444
            S   L +  + P    E              P +    P I  E P    +      + P
Sbjct: 769  SPEKLTIPTEKPTIPTE-------------KPTIPTEKPTISTEEPTTPTEETTISTEKP 815

Query: 2445 DMHFKAPNISMPDVDLNLKGPKIKGDVDVSVPEVEGKLEVPDMNIRGPKVDVNAPDVQAP 2504
             +  + P +   +   +++      +  +S  ++   +E P ++   P +    P +   
Sbjct: 816  SIPMEKPTLPTEETTTSVE------ETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPE 869

Query: 2505 DWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDIEGPDVNIEGPEGKLKG 2564
               +   K+ +P    P    E  E  ++  K  +    P +  E P ++ E P    + 
Sbjct: 870  KLTIPTEKLTIPT-EKPTIPIE--ETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEK 926

Query: 2565 PKLKMPEMNIKAPKISMP 2582
            P +   E  I   K+++P
Sbjct: 927  PTIPTEETTISTEKLTIP 944



 Score = 52.4 bits (124), Expect = 1e-05
 Identities = 72/414 (17%), Positives = 140/414 (33%), Gaps = 57/414 (13%)

Query: 1227 PDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMPKFSMPGFKGEGREVDVNLPKADIDVS 1286
            P +  K P + I+ P V  + P    + P +   K +            ++  K  I   
Sbjct: 563  PTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPT------------ISTEKPTIPSE 610

Query: 1287 GPKVDVEVPDVSLEGPEGKLKGPKF--KMPEMHFKAPKISMPDVDLNLKGPKLKGDVDVS 1344
             P +  E P +  E P    + P    + P +  + P IS     +  + P    +    
Sbjct: 611  KPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTE---- 666

Query: 1345 LPEVEGEMKVPDVDIKGPKVDISAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDV 1404
              E    M+ P +  + P +    P +    P   ++   +   K   P    E P +  
Sbjct: 667  --ETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEK---PTISPEKPTIPT 721

Query: 1405 KLP-----KADVDVSGPKMDAEVPDVNIEGPDAKLKGPKFKMPEMSIKPQKISIPDVGLH 1459
            + P     K+ +    P    E P +  E P    + P     + +I P+K++IP     
Sbjct: 722  EKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIP----- 776

Query: 1460 LKGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKVDINAPDVEVHGPDWHLKMPKVKMPKFS 1519
                        T+P      + P +  + P +    P           + P + M K +
Sbjct: 777  --------TEKPTIP-----TEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPT 823

Query: 1520 MPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPDVNLEAPEGKLKGPKFKMPSMNIQTHKI 1579
            +P       E   ++ +  +      + ++ P ++ E P    + P      + I T K+
Sbjct: 824  LP-----TEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKL 878

Query: 1580 SMPDVGLNLKAPKLK-TDVDVSLPKVEGDLKGPEIDVKAPKMDVNVGDIDIEGP 1632
            ++P      + P +   +  +S  K+    + P I  + P +      I  E P
Sbjct: 879  TIP-----TEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKP 927



 Score = 52.4 bits (124), Expect = 1e-05
 Identities = 89/435 (20%), Positives = 148/435 (34%), Gaps = 39/435 (8%)

Query: 2070 VNLPKADVVVSGPKVDVEVPDVSLEGPEGKLKGPKLKMPEMHFKAPKISMPDVDLHLKGP 2129
            ++  K  V +  P V  E P V  E P    + P +   +    + K +MP     +  P
Sbjct: 565  ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTI--P 622

Query: 2130 KVKGDVDVSLPKLEGD-----LTGPSVDVEVPDVELECPDAKLKGPKFKMPEMHFKTPKI 2184
              K  +    P +  +        P++  E P V  E P    +     M E    T K 
Sbjct: 623  SEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKP 682

Query: 2185 SMPDVNLNLKGPKVKGDMD---VSVPKVEGEMKVPDVDIRGPKVDIDAPDVDVHGPDWHL 2241
            S+P    ++   K    M+   +S  K     + P +    P +  +   +    P    
Sbjct: 683  SIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPT 742

Query: 2242 KMPKMKMPKFSMPGFKGEGPEVDVNLP-----KADVDVSGPKVDVEVPDVSLEGPEGKLK 2296
            + P +   K   P    E P      P     K  +    P +  E P +  E P    +
Sbjct: 743  EKPTIPTEK---PTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTE 799

Query: 2297 GPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVD---VSAPKLEGELKGPELDVKGPKL 2353
             P     E    T K S+P     L   +    V+   +S  KL   ++ P +  + P +
Sbjct: 800  EPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTI 859

Query: 2354 DADMPEVAVEG---PNGKWKTPKFKMPDMHFKAPKISMPDLDLHLKSPKAKGEVDVDVPK 2410
              + P ++ E    P  K   P  K P +  +   IS   L +    P  K  +  + P 
Sbjct: 860  PTEKPTISPEKLTIPTEKLTIPTEK-PTIPIEETTISTEKLTI----PTEKPTISPEKPT 914

Query: 2411 LEGDLKGPHVDVSGPDIDIEGPEGKLKGPKFKMPDMHFKAPNISMPDVDLNLKGPKIKGD 2470
            +    + P +    P I  E  E  +   K  +P    + P IS   + +  + P I  +
Sbjct: 915  I--STEKPTIPTEKPTIPTE--ETTISTEKLTIPT---EKPTISPEKLTIPTEKPTISTE 967

Query: 2471 VDVSVPEVEGKLEVP 2485
                  E   KL +P
Sbjct: 968  KPTIPTE---KLTIP 979



 Score = 52.0 bits (123), Expect = 2e-05
 Identities = 77/493 (15%), Positives = 159/493 (32%), Gaps = 47/493 (9%)

Query: 3772 GDLKGPEVDIKGPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKA 3831
            G  + P +  K P V I  P V  + P    + P +   K ++   K   P    N+P  
Sbjct: 558  GLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPS- 616

Query: 3832 DLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDM 3891
                  P +  + P +  E P    + P     +  I   K ++P  +      +    M
Sbjct: 617  ----EKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSM 672

Query: 3892 DVSLPKVEGDMQVPDLDIKGPKVDINAPDVDVRGPDWHLKMPKIKMPKISMPGFKGEGP- 3950
            +  +   E     P +  + P +    P + +       + P I   K ++P  K   P 
Sbjct: 673  EEPVIPTE----KPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPT 728

Query: 3951 -EVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLH 4009
             +  ++  K       P +  + P ++ E P    + P     ++ I   K ++P     
Sbjct: 729  EKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIP----- 783

Query: 4010 LKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFS 4069
                                 + P +  + P +  + P           + P + M K +
Sbjct: 784  --------------------TEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPT 823

Query: 4070 MPGFKGEGPEVDVNLPKADIDVSGPKVDIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKI 4129
            +P       E   ++ +  I      + ++ P I    P    + P      L +   K+
Sbjct: 824  LP-----TEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKL 878

Query: 4130 SMPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHLKMP 4189
            ++P      K      +  +S  K+    + P +  + P +  + P +  + P    +  
Sbjct: 879  TIP----TEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEET 934

Query: 4190 KVKMPKFSMPGFKGEGPDVDVNLP--KADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKM 4247
             +   K ++P  K       + +P  K  +    P +  +   +  E P    + P    
Sbjct: 935  TISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPT 994

Query: 4248 PEMNIKAPKISMP 4260
             ++    P    P
Sbjct: 995  EKLTALRPPHPSP 1007



 Score = 51.2 bits (121), Expect = 3e-05
 Identities = 94/511 (18%), Positives = 170/511 (33%), Gaps = 58/511 (11%)

Query: 3394 VQGKVKGSKFKMPFLSISS---PKVSMPDVELNLKSPKVKGDLDIAGPNLEGDFKGPKVD 3450
            +QG    S   M F+ I+    P   +P++      P V            G  + P + 
Sbjct: 513  IQGSNTASVVAMGFILINPGTCPVKVLPEL------PPVSPVSSTGPSETTGLTENPTIS 566

Query: 3451 IKAPEVNLNAPDVDVHGPDWNLKMPKMKMPKFSVSGLK------------------AEGP 3492
             K P V++  P V    P    + P +   K ++S  K                  +E P
Sbjct: 567  TKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKP 626

Query: 3493 DVAVDLP-----KGDINIEGPSMNIEGPDLNVEGPEGGLKGPKFKMPDMNIKAPKISMPD 3547
             +  + P     K  I  E P+++ E P +  E P    +     M +  I   K S+P 
Sbjct: 627  TILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPT 686

Query: 3548 IDLNLKGPKVKGDVDISLPKLEGDLKGPE---VDIKGPKVDINAPDVDVHGPDWHLKMPK 3604
               ++   K    ++ ++   E     PE   +  + P +      +    P    + P 
Sbjct: 687  EKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPT 746

Query: 3605 VKMPKFSMPGFKGEGPEVDVTL--PKADIDISGPNVDVDVPDVNIEGPDAKLKGPKFKMP 3662
            +   K ++   K   P    T+   K  I    P +  + P +  E P    + P     
Sbjct: 747  IPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTE 806

Query: 3663 EMNIKAPKISMPDFDLNLKGPKMKGDV---VVSLPKVEGDLKGPEVDIKGPKVDIDTPDI 3719
            E  I   K S+P     L   +    V    +S  K+   ++ P +  + P +  + P I
Sbjct: 807  ETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTI 866

Query: 3720 NIEGSEGKFKGPKFKIPEMHLKAPKISMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPEV 3779
            + E         K  IP   L  P    P I +         +  +S  K+    + P +
Sbjct: 867  SPE---------KLTIPTEKLTIP-TEKPTIPIE--------ETTISTEKLTIPTEKPTI 908

Query: 3780 DIKGPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPK 3839
              + P +    P +  + P    +   +   K ++P  K       + +P     +S  K
Sbjct: 909  SPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEK 968

Query: 3840 VDIDVPDVNIEGPEGKLKGPKFKMPEMNIKA 3870
              I    + I   +  +   K  +P   + A
Sbjct: 969  PTIPTEKLTIPTEKPTIPTEKPTIPTEKLTA 999



 Score = 46.2 bits (108), Expect = 0.001
 Identities = 94/486 (19%), Positives = 178/486 (36%), Gaps = 65/486 (13%)

Query: 239 AGHSK-LQVTMPGIKVGGSGVNVNAKGLDLGGRGGVQV------PAVDISSSLGGRAVE- 290
           +GH + +Q+   GI+ G +  +V A G  L   G   V      P V   SS G      
Sbjct: 500 SGHQQPMQLIFKGIQ-GSNTASVVAMGFILINPGTCPVKVLPELPPVSPVSSTGPSETTG 558

Query: 291 -VQGPSLESGDHGKIKFPTMKVPKFGVSTGREGQTPKAGLRVSAPEVSVGHKGGKPGLTI 349
             + P++ +      K PT+ + K  V+T +    PK    +   + ++  +  KP +  
Sbjct: 559 LTENPTIST------KKPTVSIEKPSVTTEKP-TVPKEKPTIPTEKPTISTE--KPTIPS 609

Query: 350 QAPQLEVSVPSANIEGLEGKLKGPQITG--PSLEGDLGLKGAKPQGHIGVDASAP--QIG 405
           + P +    P+   E      + P I    P++  +      +       + + P  +  
Sbjct: 610 EKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETT 669

Query: 406 GSITGPSVEVQAPDIDVQGPGSKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVPGV 465
            S+  P +  + P I  + P      P + + +  +S  K   +    T+PT + T+P  
Sbjct: 670 TSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTE 729

Query: 466 SGDVSLPEIATGGLEGKMKGTKVKTPEMIIQKPKISMQDVDLSLGSPKLKGDIKVSAPGV 525
              +S PE  T         T  + P +  +KP IS +        P +  + K++ P  
Sbjct: 730 KSTIS-PEKPT---------TPTEKPTIPTEKPTISPEKPTTPTEKPTISPE-KLTIP-- 776

Query: 526 QGDVKGPQVALKGSRVDIETPNLEGTLTGPRLGSPSGKTGTCRISMSEVDLNVAAPKVKG 585
               + P +  +   +  E P +           P+  T    IS  +  + +  P    
Sbjct: 777 ---TEKPTIPTEKPTIPTEKPTIS-------TEEPTTPTEETTISTEKPSIPMEKP---- 822

Query: 586 GVDVTLPRVEGKVKVPEVDVRGPK--VDVSAPDVEAHGPEWNLKMPKMKMPTFSTPGAKG 643
               TLP  E    V E  +   K  + +  P +    P    + P +     + P  K 
Sbjct: 823 ----TLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKL 878

Query: 644 EGPDVHMTLPKGDISIS---------GPKVNVEAPDVNLEGLGGKLKGPDVKLPDMSVKT 694
             P    T+P  + +IS          P ++ E P ++ E      + P +   + ++ T
Sbjct: 879 TIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTIST 938

Query: 695 PKISMP 700
            K+++P
Sbjct: 939 EKLTIP 944



 Score = 45.1 bits (105), Expect = 0.002
 Identities = 83/440 (18%), Positives = 145/440 (32%), Gaps = 63/440 (14%)

Query: 4903 SLKMPSLEISAPKVTAPDVDLHLKAPKIGFSGPKLEGGEVDLKGPKVEAPSLDVHMDSPD 4962
            S K P++ I  P VT     +  + P I    P +   +  +   K   PS     + P 
Sbjct: 566  STKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPS-----EKPT 620

Query: 4963 INIEGPDVKIPKFKKPKFGFGAKSPKADIKSPSLDV---TVPEAELNLETPEISVGGKGK 5019
            I  E P +   K   P     ++ P    + P++     TVP  E    T E +   +  
Sbjct: 621  IPSEKPTILTEKPTIP-----SEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEP 675

Query: 5020 KSKFKMPKIHMSGPKIKAKKQGFDLNVPGGEIDASLKAPDVD-----VNIAGPDAALKVD 5074
                + P I    P I  +K    +     E   S + P +      +    P    +  
Sbjct: 676  VIPTEKPSIPTEKPSIPTEKPTISME----ETIISTEKPTISPEKPTIPTEKPTIPTEKS 731

Query: 5075 VKSPKTKKTMFGKMYFPDVEFDIKSPKFKAEAPLPSPKLEGELQAPDLELSLPAIHVEGL 5134
              SP+   T   K            P    E P  SP      + P      P I  E L
Sbjct: 732  TISPEKPTTPTEK------------PTIPTEKPTISP------EKPTTPTEKPTISPEKL 773

Query: 5135 DIKAKAPKV--KMPDVDISVPKIEGDLKGPKVQANLGAPDINIEGLDAKVKTPSFGISAP 5192
             I  + P +  + P +    P I  +            P    E      + PS  +  P
Sbjct: 774  TIPTEKPTIPTEKPTIPTEKPTISTE-----------EPTTPTEETTISTEKPSIPMEKP 822

Query: 5193 QVSIPDVNVNLKGPKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGG 5252
             +   +   +++   I  +  ++ +E P +  + P    + P  S  K+ IP  K+    
Sbjct: 823  TLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPT 882

Query: 5253 -------AEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGV--DLPSVNLSMPKVSGPDLD 5303
                    E       L      P +  E P +S + P +  + P++      +S   L 
Sbjct: 883  EKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLT 942

Query: 5304 LNLKGPSLKGDLDASVPSMK 5323
            +  + P++  +   ++P+ K
Sbjct: 943  IPTEKPTISPE-KLTIPTEK 961



 Score = 33.9 bits (76), Expect = 4.9
 Identities = 29/152 (19%), Positives = 59/152 (38%), Gaps = 15/152 (9%)

Query: 5183 KTPSFGISAPQVSIPDVNVNLKGPKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIG 5242
            + P+     P VSI   +V  + P +  + P++  E P +  + P    + P     K  
Sbjct: 561  ENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPT 620

Query: 5243 IPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDL 5302
            IP  K       +  + P++  +   P +  E P +S      + P+V    P     + 
Sbjct: 621  IPSEK-----PTILTEKPTIPSE--KPTIPSEKPTIS-----TEKPTVPTEEPTTPTEET 668

Query: 5303 DLNLKGPSL---KGDLDASVPSMKVHAPGLNL 5331
              +++ P +   K  +    PS+    P +++
Sbjct: 669  TTSMEEPVIPTEKPSIPTEKPSIPTEKPTISM 700


>gi|169205253 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 3859

 Score = 60.5 bits (145), Expect = 5e-08
 Identities = 250/1036 (24%), Positives = 353/1036 (34%), Gaps = 180/1036 (17%)

Query: 1090 PKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLKG-EGPEVDV 1148
            P + G+  V  V      V +  PDV    +   +  P    P  + P+  G   P    
Sbjct: 2918 PDLSGDCPVVPVPPTDDIVVLNPPDV----VFAVVSTPVTDGPVVTDPATDGLMVPVTPA 2973

Query: 1149 NLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFK---MPEMHFKTPKISMPDVD-LHL 1204
            N   A V +S      E PDV++   +G +  P      +P+    +  +S P  D L +
Sbjct: 2974 NGSVAPVTLS------EYPDVTVTPADGTVVSPTIGGPVVPDPSADSSVVSNPTTDGLIV 3027

Query: 1205 KGPKVKGDVDVSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMP-KMKMPKFS 1263
              P + G V V V   +G +         P +  D PDV V   D  +        P F 
Sbjct: 3028 PNPLLAGPV-VPVTPTDGPL--------APVILADCPDVTVTPADGPVVCAFTTGGPVFP 3078

Query: 1264 MPGFKGEGREVDVNLPKADIDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKAPKI 1323
             P  +G             + VS P VD    D  +  P    KG     P      P I
Sbjct: 3079 DPTAEG-------------LVVSNPTVD----DPVVTNPS--TKGLVSATPADCADVPVI 3119

Query: 1324 --SMPDVDLNLKGPKLKGDVDVSLPEVEGEMKVPDVDIKGPKVDISAPDVDVHGPDWHLK 1381
                PDV +NL    +                VPD       V +S PD D+  PD   +
Sbjct: 3120 PADCPDVLVNLVNDSV----------------VPDFTADWTVVSVSPPD-DLVAPDPPDE 3162

Query: 1382 MPKVKMPKFS---MPGFKGEGPEVDVKLPKADVDVSGPKMDAEVPDVNIEGPDAKLKGPK 1438
            +P V +P      +P    +G  V V    A V    P    + PDV +   D+    P 
Sbjct: 3163 VPVVLVPITDGPVVPDLTTDGLVVSVTPAGAPVV---PVFLTDCPDVTVTPADS----PV 3215

Query: 1439 FKMPEMSIKPQKISIPDVGLHLKGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKVDINAPD 1498
               P         S+ D GL    P    D  V        +  PD    GP     APD
Sbjct: 3216 VPDPSSDGPVVADSLDDDGLV---PVTPADDSVVPDSPANGLVVPDPTTDGPV----APD 3268

Query: 1499 VEVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPDVNLEAP 1558
              V GP               +P    + P V + L         P V +  PD  L   
Sbjct: 3269 PSVDGP--------------VVPVTPADAPTVSVTLADC------PDVTVTPPD-GLVVS 3307

Query: 1559 EGKLKGPKFKMPSMNIQTHKISMPDVGLNLKAPKLKTDVDVS---LPKVEGDLKGPEI-D 1614
            + K  GP     S N      +  D       P    DV V+    P V  + + P + D
Sbjct: 3308 DSKRGGPVVTGLSTNDPVITATPADFSDVTVTPADFEDVPVTPANCPDVPVNPESPVVSD 3367

Query: 1615 VKAPKMDVNVGDID----IEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGD 1670
            +    + V V   D    +E P+               K P +  P  +  +    +  +
Sbjct: 3368 LAVDFLVVPVVPSDDLVVLEPPD---------------KVPVVPDPISNGLVVSDPITNN 3412

Query: 1671 MDVSVPKVEGEMKVPDVDIKGPKVDI---DAPDVEVHDPDWHLKMPKMKMPKFS-MPGFK 1726
               + P V+G + VP     GP   +   D PDV +   D  +        +F  +P   
Sbjct: 3413 TAATDPSVDGSV-VPVSPADGPVAPVTLADCPDVTITPADDSVVSDSKIRAEFEDVPVTI 3471

Query: 1727 AEGPEVDVNLPKADIDVSGPSVDTDAPDLDIEGPEGKLKGSKFKMPKLNIKAPKVSMPDV 1786
            A+ P V VN PK+   VS  +VD   P + I  P+  +       P+   + P V  P  
Sbjct: 3472 ADCPNVPVN-PKSGPVVSDLAVD--CPVVPIPPPDDLVA------PEPPDEVPVVPDPIT 3522

Query: 1787 D-LNLKGPKLKGEIDASVPELEGDLRGPQVDVKGPFVEAEVPDVDLECPDAKLKGPKFKM 1845
            D L +  P   G + AS P ++G +  P V   G  V   V DV +  PD     P   +
Sbjct: 3523 DSLVVSDPMTDGPV-ASDPSIDG-IVVPVVSPSGLLVLDSVADVSI-LPDTSADVPVTPV 3579

Query: 1846 PEMHFKAPKISMPDVDLHLKGPKVKGDADVSVPKLEGDLTGPS---VGVEVPDVELECPD 1902
                      S PD  +    P +  D  V +  L   +  P+   VG  VPD   + PD
Sbjct: 3580 TLADGSVVPDSAPDCPVV---PVLPTDGFVVLDLLVDGVVVPNPADVGPVVPDPTTDGPD 3636

Query: 1903 AKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDV--DVSVPKLEGDLTGPSVGVEV 1960
            +    P   +PD     P + +   D    GP V       V VP   GD    SV +  
Sbjct: 3637 SIKDFPL--VPDPWPDCPVVPVTRTD----GPVVLDSSADGVVVPVTPGD---DSVALVT 3687

Query: 1961 PDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKV 2020
            P   L  PD    GP    P        +S+ D DL +  P VK   D  VP    +  V
Sbjct: 3688 PTDNLVVPDLTTDGPVVPDPSADGPVVLVSLAD-DLLVPNPPVK---DTVVPNSVADNPV 3743

Query: 2021 PDVDIKGPKMDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVVVS 2080
                +       D P V           P+       +     EGP V        VV++
Sbjct: 3744 ALDPVT------DCPLV-----------PEPSANGLVVTDSLDEGPVVPDPSADDPVVLN 3786

Query: 2081 GPKVDVEVPDVSLEGP 2096
                 + VPD+S  GP
Sbjct: 3787 PETNGLVVPDISANGP 3802



 Score = 58.9 bits (141), Expect = 1e-07
 Identities = 208/880 (23%), Positives = 298/880 (33%), Gaps = 162/880 (18%)

Query: 2355 ADMPEVAVEGPNGKWKTPKFKMPDMHFKAPKISMPDLD------------LHLKSPKAKG 2402
            AD+P   V GP          +PD+    P + +P  D              + +P   G
Sbjct: 2905 ADVPVNPVNGP---------VVPDLSGDCPVVPVPPTDDIVVLNPPDVVFAVVSTPVTDG 2955

Query: 2403 EVDVDVPKLEGDLKGPHVDVSG----------PDIDIEGPEGKLKGPKFK---MPDMHFK 2449
             V  D P  +G L  P    +G          PD+ +   +G +  P      +PD    
Sbjct: 2956 PVVTD-PATDG-LMVPVTPANGSVAPVTLSEYPDVTVTPADGTVVSPTIGGPVVPDPSAD 3013

Query: 2450 APNISMPDVD-LNLKGPKIKGDVDVSVPEVEGKL------EVPDMNIR---GPKVDVNA- 2498
            +  +S P  D L +  P + G V V V   +G L      + PD+ +    GP V     
Sbjct: 3014 SSVVSNPTTDGLIVPNPLLAGPV-VPVTPTDGPLAPVILADCPDVTVTPADGPVVCAFTT 3072

Query: 2499 -----PDVQAPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDIEGPDV 2553
                 PD  A    +  P +  P  + P  K        +   ADV    P +  + PDV
Sbjct: 3073 GGPVFPDPTAEGLVVSNPTVDDPVVTNPSTKGLVSATPADC--ADV----PVIPADCPDV 3126

Query: 2554 NIEGPEGKLKGPKLKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEV 2613
             +      +      +P+       +S+   D  L  P    +V V L  +      P++
Sbjct: 3127 LVNLVNDSV------VPDFTADWTVVSVSPPD-DLVAPDPPDEVPVVLVPITDGPVVPDL 3179

Query: 2614 DIKGPKVDINAPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPK 2673
               G  V +      V  P +    P V +     P       DG V     D D   P 
Sbjct: 3180 TTDGLVVSVTPAGAPVV-PVFLTDCPDVTVTPADSPVVPDPSSDGPVVADSLDDDGLVPV 3238

Query: 2674 VDIEGPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVE 2733
               +   V    P+    G    +P+     P    P +D    GP V            
Sbjct: 3239 TPADDSVV----PDSPANG--LVVPDPTTDGPVAPDPSVD----GPVV------------ 3276

Query: 2734 GDLKGPEVDIKGPKVDI---DAPDVDVHGPDWHLKMPKIKMPKISMPGFKGEGPDV---- 2786
                 P      P V +   D PDV V  PD  L +   K     + G     P +    
Sbjct: 3277 -----PVTPADAPTVSVTLADCPDVTVTPPDG-LVVSDSKRGGPVVTGLSTNDPVITATP 3330

Query: 2787 ----DVNLPKADIDVSGPKVDVECPDV--NIEGPEGKWKSPKFKMP-----------EMH 2829
                DV +  AD +   P     CPDV  N E P     +  F +            E  
Sbjct: 3331 ADFSDVTVTPADFE-DVPVTPANCPDVPVNPESPVVSDLAVDFLVVPVVPSDDLVVLEPP 3389

Query: 2830 FKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPEVDLKGPKVDI---DVPDVNVQ 2886
             K P +  P  +  +    I  +   T P V+G +  P     GP   +   D PDV + 
Sbjct: 3390 DKVPVVPDPISNGLVVSDPITNNTAATDPSVDGSVV-PVSPADGPVAPVTLADCPDVTIT 3448

Query: 2887 GPDWHLKMPKMKMPKFS-MPGFKAEGPEVDVNLPKADVDVSGPKVDVEGPDVNIEGPEGK 2945
              D  +        +F  +P   A+ P V VN PK+   VS   VD   P V I  P+  
Sbjct: 3449 PADDSVVSDSKIRAEFEDVPVTIADCPNVPVN-PKSGPVVSDLAVDC--PVVPIPPPDDL 3505

Query: 2946 LKGPKFKMPEMNIKAPKIPMPDFD-LHLKGPKVKGDVDISLPKVEGDLKGPEVDIRGPQV 3004
            +       PE   + P +P P  D L +  P   G V  S P ++G +  P V   G  V
Sbjct: 3506 VA------PEPPDEVPVVPDPITDSLVVSDPMTDGPV-ASDPSIDG-IVVPVVSPSGLLV 3557

Query: 3005 DIDVPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVN--LPK-----ADLDVSGPK 3057
               V DV +  PD    +P   +            PD  V   LP       DL V G  
Sbjct: 3558 LDSVADVSIL-PDTSADVPVTPVTLADGSVVPDSAPDCPVVPVLPTDGFVVLDLLVDGVV 3616

Query: 3058 V----DID--VPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPD----IDLNLKG---PK 3104
            V    D+   VPD   +GP+     P    P  +     ++  D    +D +  G   P 
Sbjct: 3617 VPNPADVGPVVPDPTTDGPDSIKDFPLVPDPWPDCPVVPVTRTDGPVVLDSSADGVVVPV 3676

Query: 3105 VKGDMDVSLPKVEGDMKVPDVDIKGPKVDINAPDVDVQGP 3144
              GD  V+L     ++ VPD+   GP V    PD    GP
Sbjct: 3677 TPGDDSVALVTPTDNLVVPDLTTDGPVV----PDPSADGP 3712



 Score = 52.4 bits (124), Expect = 1e-05
 Identities = 203/877 (23%), Positives = 297/877 (33%), Gaps = 158/877 (18%)

Query: 588  DVTLPRVEGKVKVPEVDVRGPKVDVSAPDVEAHGPEWNLKMPKMKMPTFSTPGAKG---- 643
            DV +  V G V VP++    P V V   D         L  P +     STP   G    
Sbjct: 2906 DVPVNPVNGPV-VPDLSGDCPVVPVPPTDDIVV-----LNPPDVVFAVVSTPVTDGPVVT 2959

Query: 644  ----EGPDVHMTLPKGDISISGPKVNVEAPDVNLEGLGGKLKGPDVK---LPDMSVKTPK 696
                +G  V +T   G ++   P    E PDV +    G +  P +    +PD S  +  
Sbjct: 2960 DPATDGLMVPVTPANGSVA---PVTLSEYPDVTVTPADGTVVSPTIGGPVVPDPSADSSV 3016

Query: 697  ISMPDVDLHVKGTKVKGEYDVTVPKLEGELKGPKVDIDAPDVDVHGPDWHLKMPKMK--- 753
            +S P  D  +    +     V V   +G L  P +  D PDV V   D  +         
Sbjct: 3017 VSNPTTDGLIVPNPLLAGPVVPVTPTDGPL-APVILADCPDVTVTPADGPVVCAFTTGGP 3075

Query: 754  -MPKFSVPGFKAEGPEVD---VNLPKADVDISG--------PKIDVTAPDVSIEEPEGKL 801
              P  +  G     P VD   V  P     +S         P I    PDV +      +
Sbjct: 3076 VFPDPTAEGLVVSNPTVDDPVVTNPSTKGLVSATPADCADVPVIPADCPDVLVNLVNDSV 3135

Query: 802  KGPKFKMPEMNIKVPKISMPDVDLHLKGPNVKGEYDVTMPKVESEIKVPDVELKSAKMDI 861
              P F     +  V  +S PD    L  P+   E  V +  +     VPD+      + +
Sbjct: 3136 V-PDFTA---DWTVVSVSPPD---DLVAPDPPDEVPVVLVPITDGPVVPDLTTDGLVVSV 3188

Query: 862  -------------DVPDVEVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDI 908
                         D PDV V   D     P +  P    P   A+  + D  +P    D 
Sbjct: 3189 TPAGAPVVPVFLTDCPDVTVTPAD----SPVVPDPSSDGP-VVADSLDDDGLVPVTPADD 3243

Query: 909  S----GPKVGVEVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGPKVKGEY 964
            S     P  G+ VPD   +GP           P+ ++  P + +   D            
Sbjct: 3244 SVVPDSPANGLVVPDPTTDGPVA---------PDPSVDGPVVPVTPADAP---------- 3284

Query: 965  DMTVPKLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGPEF-DVNLS 1023
              TV     D   P V V+ PD  +   D     P +     + P +     +F DV ++
Sbjct: 3285 --TVSVTLADC--PDVTVTPPD-GLVVSDSKRGGPVVTGLSTNDPVITATPADFSDVTVT 3339

Query: 1024 KANVDISAPKVDTNAPDLSLEGPEGKLKG---------PKFKMPEMHFRAPKMSLPDVDL 1074
             A+ +   P    N PD+ +  PE  +           P     ++    P   +P V  
Sbjct: 3340 PADFE-DVPVTPANCPDVPVN-PESPVVSDLAVDFLVVPVVPSDDLVVLEPPDKVPVVPD 3397

Query: 1075 DLKG-----PKMKGNVDISAPKIEGEMQVPDVDIRGPKVDIK---APDVEGQGLDWSLKI 1126
             +         +  N   + P ++G + VP     GP   +     PDV     D S+  
Sbjct: 3398 PISNGLVVSDPITNNTAATDPSVDGSV-VPVSPADGPVAPVTLADCPDVTITPADDSVVS 3456

Query: 1127 PKMKMPKFS-MPSLKGEGPEVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKM 1185
                  +F  +P    + P V VN PK+  VVS   VD   P V +  P+  +       
Sbjct: 3457 DSKIRAEFEDVPVTIADCPNVPVN-PKSGPVVSDLAVD--CPVVPIPPPDDLVA------ 3507

Query: 1186 PEMHFKTPKISMPDVD-LHLKGPKVKGDVDVSVPKVEGEMKVPDVEIKGPKMDIDAPDVE 1244
            PE   + P +  P  D L +  P   G V  S P ++G + VP V   G  +     DV 
Sbjct: 3508 PEPPDEVPVVPDPITDSLVVSDPMTDGPV-ASDPSIDG-IVVPVVSPSGLLVLDSVADVS 3565

Query: 1245 VQGPDWHLKMPKMKM------------------PKFSMPGFKGEGREVDVNLPKADIDVS 1286
            +  PD    +P   +                  P     GF      VD  +     DV 
Sbjct: 3566 IL-PDTSADVPVTPVTLADGSVVPDSAPDCPVVPVLPTDGFVVLDLLVDGVVVPNPADV- 3623

Query: 1287 GPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKAPKISMPD----VDLNLKG---PKLKG 1339
            GP V    PD + +GP+     P    P        ++  D    +D +  G   P   G
Sbjct: 3624 GPVV----PDPTTDGPDSIKDFPLVPDPWPDCPVVPVTRTDGPVVLDSSADGVVVPVTPG 3679

Query: 1340 DVDVSLPEVEGEMKVPDVDIKGPKVDISAPDVDVHGP 1376
            D  V+L      + VPD+   GP V    PD    GP
Sbjct: 3680 DDSVALVTPTDNLVVPDLTTDGPVV----PDPSADGP 3712



 Score = 46.6 bits (109), Expect = 7e-04
 Identities = 293/1320 (22%), Positives = 429/1320 (32%), Gaps = 288/1320 (21%)

Query: 2830 FKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPEVDLKGPKVDIDVPDVNVQGPD 2889
            F T  I +PD+  +   P   GD D   P   GD   P + +        VP     GP 
Sbjct: 2688 FPTDGILVPDLADDPVVPVTPGD-DPVVPVTPGD--DPVIPVTPADDGPFVPVTPAVGP- 2743

Query: 2890 WHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDVSGPKVDVEGPDVNIEGPEGKLKGP 2949
                +P +      +P    + P + V  P   + V     D +GP+V++      + GP
Sbjct: 2744 ---VVPDLTADDSVVPDSLTDDPVISV-CPDDGLVVPDTVRDSDGPEVSVY----PVTGP 2795

Query: 2950 KFKMPEMNIKAPKIPMPDFDLHLKGP--------KVKGDVDISLPKVEGDL-KGPEVDIR 3000
                   +     +P+ D  + L  P         V   + +  P ++G +   P VD  
Sbjct: 2796 VVTDSAADCPVVSVPLTDGLVVLCPPDEVPAVHDSVTNGLVVPDPVIDGPVFSNPSVD-- 2853

Query: 3001 GPQVDIDVPD-VGVQGPDWHLKMPKVKMPKFSMPGFKGEGPD-VDVNLPKADLDVSGPKV 3058
            GP V +   D  GV  PD     P V  P    P       D +DV +  AD        
Sbjct: 2854 GPIVPVASADNPGV--PDPIRAFPVVPKPSTFSPVVTSTPADWIDVIVTPADC------- 2904

Query: 3059 DIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDID--LNLKGPKVKGDMDVSLPKV 3116
              DVP   + GP          +P+++   P + +P  D  + L  P V   + VS P  
Sbjct: 2905 -ADVPVNPVNGPV---------VPDLSGDCPVVPVPPTDDIVVLNPPDVVFAV-VSTPVT 2953

Query: 3117 EGD---------MKVPDVDIKGPKVDINA---PDVDVQGPDWHLKMPKIKMPKISMPGFK 3164
            +G          + VP     G    +     PDV V   D  +  P I  P +  P   
Sbjct: 2954 DGPVVTDPATDGLMVPVTPANGSVAPVTLSEYPDVTVTPADGTVVSPTIGGPVVPDPSAD 3013

Query: 3165 GE------------------GPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLK--- 3203
                                GP V V      L    P +  D PDV +   D  +    
Sbjct: 3014 SSVVSNPTTDGLIVPNPLLAGPVVPVTPTDGPL---APVILADCPDVTVTPADGPVVCAF 3070

Query: 3204 ---GPKFKMPEMNIKAPKISMPDLDLNL-KGPKMKGEVDVSLANVEGDLKGPALDIKGPK 3259
               GP F  P+   +   +S P +D  +   P  KG V  + A+          D+  P 
Sbjct: 3071 TTGGPVF--PDPTAEGLVVSNPTVDDPVVTNPSTKGLVSATPAD--------CADV--PV 3118

Query: 3260 IDVDAPDIDIHGPDAKLKGPKLKMPDMHVNMPKISMPEIDLNLKGSKLKGDVDVSGPKLE 3319
            I  D PD+ ++  +  +      +PD   +   +S+   D            D+  P   
Sbjct: 3119 IPADCPDVLVNLVNDSV------VPDFTADWTVVSVSPPD------------DLVAPDPP 3160

Query: 3320 GDIKAPSLDIK-GPEVDVSGPKLNIEGKSKKSRFKLPKFNFSGSKVQTPEVDV-KGKKPD 3377
             ++    + I  GP V    P L  +G              S +    P V V     PD
Sbjct: 3161 DEVPVVLVPITDGPVV----PDLTTDG-----------LVVSVTPAGAPVVPVFLTDCPD 3205

Query: 3378 IDITGPKVDINAPDVEVQGKVKGSKFKMPFLSISSPKVS--MPDVELN-LKSPKVKGDLD 3434
            + +T P      PD    G V         L   +P     +PD   N L  P    D  
Sbjct: 3206 VTVT-PADSPVVPDPSSDGPVVADSLDDDGLVPVTPADDSVVPDSPANGLVVPDPTTDGP 3264

Query: 3435 IA-GPNLEGDFKGPKVDIKAPEVNL---NAPDVDVHGPDWNLKMPKMKMPKFSVSGLKAE 3490
            +A  P+++G    P     AP V++   + PDV V  PD  L +   K     V+GL   
Sbjct: 3265 VAPDPSVDGPVV-PVTPADAPTVSVTLADCPDVTVTPPD-GLVVSDSKRGGPVVTGLSTN 3322

Query: 3491 GP----------DVAV------DLPKGDINIEGPSMNIEGP---DLNVEGPEGGLKGPKF 3531
             P          DV V      D+P    N     +N E P   DL V+     L  P  
Sbjct: 3323 DPVITATPADFSDVTVTPADFEDVPVTPANCPDVPVNPESPVVSDLAVDF----LVVPVV 3378

Query: 3532 KMPDMNIKAPKISMPDIDLNLKGPKVKGDVDISLPKLEGDLKGPEVDIKGPKVDINAPDV 3591
               D+ +  P   +P +   +    V  D       +  +    +  + G  V ++  D 
Sbjct: 3379 PSDDLVVLEPPDKVPVVPDPISNGLVVSD------PITNNTAATDPSVDGSVVPVSPAD- 3431

Query: 3592 DVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVTLPKADIDISGPNVDVDVPDVNIE-GP 3650
                                       GP   VTL              D PDV I    
Sbjct: 3432 ---------------------------GPVAPVTL-------------ADCPDVTITPAD 3451

Query: 3651 DAKLKGPKFKMPEMNIKAPKISMPDFDLNLKGPKMKGDVVVSLPKVE----GDLKGPEVD 3706
            D+ +   K +    ++       P+  +N K   +  D+ V  P V      DL  PE  
Sbjct: 3452 DSVVSDSKIRAEFEDVPVTIADCPNVPVNPKSGPVVSDLAVDCPVVPIPPPDDLVAPEPP 3511

Query: 3707 IKGPKVDIDTPDINIEGSEGKFKGPKFKIPEMHLKAPKISMPDIDLNLKGPKVKGDVDVS 3766
             + P V     D ++  S+    GP    P +      +  P   L L       DV + 
Sbjct: 3512 DEVPVVPDPITD-SLVVSDPMTDGPVASDPSIDGIVVPVVSPSGLLVLDSV---ADVSI- 3566

Query: 3767 LPKMEGDLKGPEVDIK-GPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVD 3825
            LP    D+    V +  G  V  +APD  V             +P     GF      VD
Sbjct: 3567 LPDTSADVPVTPVTLADGSVVPDSAPDCPV-------------VPVLPTDGFVVLDLLVD 3613

Query: 3826 VNLPKADLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPD----IDLN 3881
              +     DV GP V    PD   +GP+     P    P  +     ++  D    +D +
Sbjct: 3614 GVVVPNPADV-GPVV----PDPTTDGPDSIKDFPLVPDPWPDCPVVPVTRTDGPVVLDSS 3668

Query: 3882 LKG---PKVKGDMDVSLPKVEGDMQVPDLDIKGPKVDINAPDVDVRGPDWHLKMPKIKMP 3938
              G   P   GD  V+L     ++ VPDL   GP V                        
Sbjct: 3669 ADGVVVPVTPGDDSVALVTPTDNLVVPDLTTDGPVV------------------------ 3704

Query: 3939 KISMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGP---DAKLKGPKFKMPEMN 3995
                P    +GP V V+L    L  + P  D  VP+   + P   D     P    P  N
Sbjct: 3705 ----PDPSADGPVVLVSLADDLLVPNPPVKDTVVPNSVADNPVALDPVTDCPLVPEPSAN 3760

Query: 3996 IKAPKISMPDFDLHLKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKVDIDAPDVDVHGPD 4055
                  S+ +  +    P    D  V L      L  P++   GP V    PD    G D
Sbjct: 3761 GLVVTDSLDEGPV---VPDPSADDPVVLNPETNGLVVPDISANGPVV----PDTPTDGSD 3813



 Score = 37.7 bits (86), Expect = 0.34
 Identities = 242/1174 (20%), Positives = 374/1174 (31%), Gaps = 268/1174 (22%)

Query: 1126 IPKMKMPKFSMPSLKGEGPEVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKM 1185
            +P +      +P    + P + V  P   +VV     D + P+VS+    G +      +
Sbjct: 2745 VPDLTADDSVVPDSLTDDPVISV-CPDDGLVVPDTVRDSDGPEVSVYPVTGPV------V 2797

Query: 1186 PEMHFKTPKISMPDVD-LHLKGPKVKGDVDVSVPKVEGEMKVPDVEIKGPKMD---IDAP 1241
             +     P +S+P  D L +  P    +V      V   + VPD  I GP      +D P
Sbjct: 2798 TDSAADCPVVSVPLTDGLVVLCPP--DEVPAVHDSVTNGLVVPDPVIDGPVFSNPSVDGP 2855

Query: 1242 DVEVQG------PDWHLKMPKMKMPKFSMPGFKGEGREVDVNLPKADIDVSGPKVDVEVP 1295
             V V        PD     P +  P    P        V  + P   IDV      +  P
Sbjct: 2856 IVPVASADNPGVPDPIRAFPVVPKPSTFSP--------VVTSTPADWIDV------IVTP 2901

Query: 1296 DVSLEGPEGKLKGPKFKMPEMHFKAPKISMPDVD----LN--------LKGPKLKGDVDV 1343
                + P   + GP   +P++    P + +P  D    LN        +  P   G V V
Sbjct: 2902 ADCADVPVNPVNGPV--VPDLSGDCPVVPVPPTDDIVVLNPPDVVFAVVSTPVTDGPV-V 2958

Query: 1344 SLPEVEGEMKVPDVDIKGPKVDISA---PDVDVHGPDWHLKMPKVKMPKFSMPGFKGE-- 1398
            + P  +G M VP     G    ++    PDV V   D  +  P +  P    P       
Sbjct: 2959 TDPATDGLM-VPVTPANGSVAPVTLSEYPDVTVTPADGTVVSPTIGGPVVPDPSADSSVV 3017

Query: 1399 ----------------GPEVDVKLPKADVDVSGPKMDAEVPDVNIEGPDAKLK------G 1436
                            GP V V      +    P + A+ PDV +   D  +       G
Sbjct: 3018 SNPTTDGLIVPNPLLAGPVVPVTPTDGPL---APVILADCPDVTVTPADGPVVCAFTTGG 3074

Query: 1437 PKFKMPEMSIKPQKISIPDVGLHLKGPKMKGDYDVTVPKVEGEIKAPDVDIKG-PKVDIN 1495
            P F  P              GL +  P +  D  VT P  +G + A   D    P +  +
Sbjct: 3075 PVFPDPTAE-----------GLVVSNPTVD-DPVVTNPSTKGLVSATPADCADVPVIPAD 3122

Query: 1496 APDVEVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPDVNL 1555
             PDV V+            +    +P F  +   V ++ P     +  P    +VP V +
Sbjct: 3123 CPDVLVN-----------LVNDSVVPDFTADWTVVSVSPPD---DLVAPDPPDEVPVVLV 3168

Query: 1556 EAPEGKLKGPKFKMPSMNIQTHKISMPDVGLNLKAPKLKTDVDVSLPKVEGDLKGPEIDV 1615
               +G +      +P +      +S+   G  +    L    DV++   +  +      V
Sbjct: 3169 PITDGPV------VPDLTTDGLVVSVTPAGAPVVPVFLTDCPDVTVTPADSPV------V 3216

Query: 1616 KAPKMD--VNVGDIDIEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDMDV 1673
              P  D  V    +D +G           +P+       +  P  D    GP        
Sbjct: 3217 PDPSSDGPVVADSLDDDGLVPVTPADDSVVPDSPANGLVVPDPTTD----GPVAPD---- 3268

Query: 1674 SVPKVEGEMKVPDVDIKGPKVDI---DAPDVEVHDPDWHLKMPKMKMPKFSMPGFKAEGP 1730
              P V+G + VP      P V +   D PDV V  PD  L +   K     + G     P
Sbjct: 3269 --PSVDGPV-VPVTPADAPTVSVTLADCPDVTVTPPDG-LVVSDSKRGGPVVTGLSTNDP 3324

Query: 1731 EVDVNLPKADIDVSGPSVDTDAPDLDIEGPEGKLKGSKFKMPKLNIKAPKVSMPDVDLNL 1790
             +      AD        D      D E                ++     + PDV +N 
Sbjct: 3325 VITAT--PADFS------DVTVTPADFE----------------DVPVTPANCPDVPVNP 3360

Query: 1791 KGPKLKGEIDASVPELEGDLRGPQVDVKGPFVEAEVPDVDLECPDAKLKGPKFKMPEMHF 1850
            + P         V +L  D     V      V  E PD                      
Sbjct: 3361 ESPV--------VSDLAVDFLVVPVVPSDDLVVLEPPD---------------------- 3390

Query: 1851 KAPKISMPDVDLHLKGPKVKGDADVSVPKLEGDLT--GPSVGVEVPDVELECPDAKLKGP 1908
            K P +  P  +  +    +  +   + P ++G +    P+ G   P    +CPD  +   
Sbjct: 3391 KVPVVPDPISNGLVVSDPITNNTAATDPSVDGSVVPVSPADGPVAPVTLADCPDVTIT-- 3448

Query: 1909 KFKMPDMHFKAPKISMPDVDLHLKGPKVKG---DVDVSVPKLEGDLTGPSVGVEVPDVEL 1965
                            P  D  +   K++    DV V++         P  G  V D+ +
Sbjct: 3449 ----------------PADDSVVSDSKIRAEFEDVPVTIADCPNVPVNPKSGPVVSDLAV 3492

Query: 1966 ECPDAKLKGPK-FKMPEMHFKTPKISMPDVD-LHLKGPKVKGDMDVSVPKVEGEMKVPDV 2023
            +CP   +  P     PE   + P +  P  D L +  P   G +  S P ++G + VP V
Sbjct: 3493 DCPVVPIPPPDDLVAPEPPDEVPVVPDPITDSLVVSDPMTDGPV-ASDPSIDG-IVVPVV 3550

Query: 2024 DIKGPKMDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVVVSGPK 2083
               G  +     DV +  PD    +P         P   A+G  V  + P   VV   P 
Sbjct: 3551 SPSGLLVLDSVADVSIL-PDTSADVPVT-------PVTLADGSVVPDSAPDCPVVPVLPT 3602

Query: 2084 VDVEVPDVSLEGPEGKLKGPKLKMPEMHFKAPKISMPDVDLHLKGPKVKGDVDVSLPKLE 2143
                V D+ ++G         + +P      P +  P  D    GP    D  +      
Sbjct: 3603 DGFVVLDLLVDG---------VVVPNPADVGPVVPDPTTD----GPDSIKDFPL------ 3643

Query: 2144 GDLTGPSVDVEVPDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMD 2203
                       VPD   +CP          +P      P +     +  +  P   GD  
Sbjct: 3644 -----------VPDPWPDCP---------VVPVTRTDGPVVLDSSAD-GVVVPVTPGDDS 3682

Query: 2204 VSVPKVEGEMKVPDVDIRGPKVDIDAPDVDVHGP 2237
            V++      + VPD+   GP V    PD    GP
Sbjct: 3683 VALVTPTDNLVVPDLTTDGPVV----PDPSADGP 3712


>gi|224589132 hypothetical protein LOC100132406 [Homo sapiens]
          Length = 3628

 Score = 58.2 bits (139), Expect = 2e-07
 Identities = 241/1236 (19%), Positives = 447/1236 (36%), Gaps = 173/1236 (13%)

Query: 3833 LDVSGPKVDIDVPDVNIEGPEGKLK--------GPKFKMPEMNIKAPKISMPDIDLNLKG 3884
            LD  GP+V  D  D     P G L+           F + E       + M +I+   K 
Sbjct: 2090 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIE---KY 2146

Query: 3885 PKVKGDMDVSLPKVEGDMQVPDLDIKGPKVDINAPDVDVRGPDWHLKMPKIKMPKISMPG 3944
             +V+ D D S P++  ++    LD K P+V  ++ D     P  +L++P +  P      
Sbjct: 2147 QEVEEDQDPSCPRLSREL----LDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP------ 2196

Query: 3945 FKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP 4004
            +      ++       LDV   ++  D  +   +GP      P+     + +  P++   
Sbjct: 2197 YSSAVYSLEEQYLGLALDVD--RIKKDQEEEEDQGPPC----PRLSRELLEVVEPEVLQD 2250

Query: 4005 DFDLHLKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVK 4064
              D     P    +   S         A E +  G  +D+   +    G     +  K +
Sbjct: 2251 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKE 2310

Query: 4065 MPKFSMPGFKGEGPEVDVNLPKADIDVSGPKVDIDTPDIDIHGPEGKLK--------GPK 4116
              +    G + + P     L +  +D  GP+V  D+ D     P G L+           
Sbjct: 2311 RRRGRKEGEEDQNPPCP-RLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSA 2369

Query: 4117 FKMPDLHLKAPKISMPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDVPD 4176
            F + +       + M E++   K  +++ D D S P++  +L    +D K P+V  D  D
Sbjct: 2370 FYVLEQQHVGLAVDMDEIE---KYQEVEEDQDPSCPRLSREL----LDEKEPEVLQDSLD 2422

Query: 4177 VDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGP 4236
                 P  +L++P +  P +S   +  E   + + L   D+D    ++  D  +   +GP
Sbjct: 2423 RCYSTPSGYLELPDLGQP-YSSAVYSLEEQYLGLAL---DVD----RIKKDQEEEEDQGP 2474

Query: 4237 DAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGP 4296
                  P+     + +  P++     D     P    +   S           E +  G 
Sbjct: 2475 PC----PRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGF 2530

Query: 4297 KVDIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVTLPKADIEISGPKVDIDA 4356
             +D+   +    G     +  K +  +    G + + P     L +  ++  GP+V  D+
Sbjct: 2531 SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCP-RLSRELLDEKGPEVLQDS 2589

Query: 4357 PDVSIEGPDAKLK--------GPKFKMPEMNIKAPKISMPDIDFNLKGPKVKGDVDVSLP 4408
             D     P   L+           F + E       + M +I+   K  +V+ D D S P
Sbjct: 2590 LDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIE---KYQEVEEDQDPSCP 2646

Query: 4409 KVEGDLKGPEIDIKGPSLDIDTPDVNIEGPEGKLKGPKFKMPEMN----IKAPKISMP-D 4463
            ++  +L    +D K P +  D+ D     P G L+ P    P  +    ++   + +  D
Sbjct: 2647 RLSREL----LDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD 2702

Query: 4464 FDLHLKGPKVKGDVDVSLPKVESDL-----------------KGPEVDIEGPEG-KLKGP 4505
             D   K  + + D     P++  +L                   P   +E P+  +  G 
Sbjct: 2703 VDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGS 2762

Query: 4506 KFKMPDVHFKSPQISMSDIDLNLKGPKIKG----------------DMDISVPKLEGDLK 4549
             F   +       + + +I+   KG K +G                D +   P+L  +L 
Sbjct: 2763 SFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL- 2821

Query: 4550 GPKVDVKGPKVGIDTPDIDIHGPEGKLK--------GPKFKMPDLHLKAPKISMPEVDLN 4601
               +D KGP+V  D+ D     P G L+           F + +       + M E++  
Sbjct: 2822 ---LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIE-- 2876

Query: 4602 LKGPKVKGDMDISLPKVEGDLKGPEVDIRDPKVDIDVPDVDVQGPDWHLKMPKVKMPKFS 4661
             K  +V+ D D S P++  +L    +D ++P+V  D  D     P  +L++P +  P +S
Sbjct: 2877 -KYQEVEEDQDPSCPRLSREL----LDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP-YS 2930

Query: 4662 MPGFKGEGPDVDVNLPKADIDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMSIKAPKI 4721
               +  E   + + L   D+D    ++  D  +   +GP      P+     + +  P++
Sbjct: 2931 SAVYSLEEQYLGLAL---DVD----RIKKDQEEEEDQGPPC----PRLSRELLEVVEPEV 2979

Query: 4722 SMPDIDLNLKGPKVKGDVDVTLPKVEGDLKGPEADIKGPKVDINTPDVDVHGPDWHLKMP 4781
                +D     P    +   +           E    G  +D+   +    G     +  
Sbjct: 2980 LQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRS 3039

Query: 4782 KVKMPKFSMPGFKGEGPDVDVSLPKADIDVSGPKVDVDIPDVNIEGPDAKLK----GPKF 4837
            K +  +    G + + P     L +  +D  GPKV  D  D     P   L+       +
Sbjct: 3040 KKERRRGRKEGEEDQNPPCP-RLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPY 3098

Query: 4838 KMPEINIKAPKISIP-DVDLDLKGPKVKGDFDVSVPKVEGTLKGPEVDLKGPRLDFEGPD 4896
            +     ++  ++ +  D+D   K  +V+ D D S P++   L    +D KGP +  +  D
Sbjct: 3099 RSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSREL----LDEKGPEVLQDSLD 3154

Query: 4897 AKLSGPSLKMPSLEISAPKVTAPDVDLHLKAPKIGF-------------------SGPKL 4937
               S PS  +   +   P  +A  +   L+  ++G                    S P+L
Sbjct: 3155 RCYSTPSGCLELCDSCQPYRSAFYI---LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRL 3211

Query: 4938 EGGEVDLKGPKVEAPSLDVHMDSPDINIEGPDVKIP 4973
                +D K P+V   SLD    +P   +E PD+  P
Sbjct: 3212 SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 3247



 Score = 42.4 bits (98), Expect = 0.014
 Identities = 161/806 (19%), Positives = 293/806 (36%), Gaps = 133/806 (16%)

Query: 4335 DVDVTLPKADIEI---SGPKVDIDAPDVSIEGPDAKLKGPKFKMPEMN----IKAPKISM 4387
            D + T P+   E+    GP+V  D+ D     P   L+      P  +    ++  ++ +
Sbjct: 611  DQEATGPRLSRELLDEKGPEVFQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGL 670

Query: 4388 P-DIDFNLKGPKVKGDVDVSLPKVEGDLKGPEIDIKGPSLDIDTPDVNIEGPEGKLKGPK 4446
              D+D   K  +V+ D D S P++  +L    +D K P +  D+ D     P G L+ P 
Sbjct: 671  AIDMDEIEKYQEVEEDQDPSCPRLSREL----LDEKEPEVLQDSLDRCYSTPSGYLELPD 726

Query: 4447 FKMPEMN----IKAPKISMP-DFDLHLKGPKVKGDVDVSLPKVESDL------------- 4488
               P  +    ++   + +  D D   K  + + D     P++  +L             
Sbjct: 727  LGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSL 786

Query: 4489 ----KGPEVDIEGPEG-KLKGPKFKMPDVHFKSPQISMSDIDLNLKGPKIKG-------- 4535
                  P   +E P+  +  G  F   +       + + +I+   KG K +G        
Sbjct: 787  DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 846

Query: 4536 --------DMDISVPKLEGDLKGPKVDVKGPKVGIDTPDIDIHGPEGKLK--------GP 4579
                    D +   P+L  +L    +D KGP+V  D+ D     P G L+          
Sbjct: 847  RGRKEGEEDQNPPCPRLSREL----LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRS 902

Query: 4580 KFKMPDLHLKAPKISMPEVDLNLKGPKVKGDMDISLPKVEGDLKGPEVDIRDPKVDIDVP 4639
             F + +       + M E++   K  +V+ D D S P++  +L    +D ++P+V  D  
Sbjct: 903  AFYVLEQQRVGFAVDMDEIE---KYQEVEEDQDPSCPRLSREL----LDEKEPEVLQDSL 955

Query: 4640 DVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADIDVSGPKVDVDVPDVNIEG 4699
            D     P  +L++P +  P +S   +  E   + + L   D+D    ++  D  +   +G
Sbjct: 956  DRCYSTPSGYLELPDLGQP-YSSAVYSLEEQYLGLAL---DVD----RIKKDQEEEEDQG 1007

Query: 4700 PDAKLKGPKFKMPEMSIKAPKISMPDIDLNLKGPKVKGDVDVTLPKVEGDLKGPEADIKG 4759
            P      P+     + +  P++    +D     P    +   +           E    G
Sbjct: 1008 PPC----PRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVG 1063

Query: 4760 PKVDINTPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVSLPKADIDVSGPKVDVD 4819
              +D+   +    G     +  K +  +    G + + P     L +  +D  GP+V  D
Sbjct: 1064 FSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCP-RLSRELLDEKGPEVLQD 1122

Query: 4820 IPDVNIEGPDAKLKGPKFKMPEIN----IKAPKISIP-DVDLDLKGPKVKGDFDVSVPKV 4874
              D     P   L+      P  +    ++  ++    D+D   K  +V+ D D S P++
Sbjct: 1123 SLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRL 1182

Query: 4875 EGTL---KGPEVDLKGPRLDFEGPDAKLSGPSLKMP-------------SLEISAPKVTA 4918
               L   K PEV        +  P   L  P L  P              L +   ++  
Sbjct: 1183 SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKK 1242

Query: 4919 PDVDLHLKAPKIGFSGPKLEGGEVDLKGPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKP 4978
             + +   + P      P+L    +++  P+V   SLD    +P   +E PD   P     
Sbjct: 1243 DEEEEEDQDPPC----PRLSRELLEVVAPEVLQDSLDRCYSTPSSCLEQPDSCQP----- 1293

Query: 4979 KFGFGAKSPKADIKSPSLDVTVPEAELNLETPEISVGGKGKKSKFKMPKIHMSGPKIKAK 5038
               +G+     + K             +L+  EI   GKGKK + +  K      + + +
Sbjct: 1294 ---YGSSFYALEEK---------HVGFSLDVGEIEKKGKGKKRRGRRSK----KERRRGR 1337

Query: 5039 KQG-FDLNVPGGEIDASL---KAPDV 5060
            K+G  D N P   +   L   K P+V
Sbjct: 1338 KEGEEDQNPPCPRLSRELLDEKGPEV 1363


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 58.2 bits (139), Expect = 2e-07
 Identities = 128/444 (28%), Positives = 167/444 (37%), Gaps = 75/444 (16%)

Query: 5206 PKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGD 5265
            P +KG+    G  GP+    GP+ +         + G PG     G       LP   G 
Sbjct: 383  PGMKGEAGPTGARGPE----GPQGQ-------RGETGPPGPVGSPG-------LPGAIGT 424

Query: 5266 LRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDL-DASVPSMKV 5324
               P  K  GP  S   PG   P  +   P   GP      +G  ++G   D  VP  K 
Sbjct: 425  DGTPGAK--GPTGS---PGTSGPPGSAGPPGSPGPQGSTGPQG--IRGQPGDPGVPGFKG 477

Query: 5325 HAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAP-DVTLRGPSLQGDLAVSGDIKCP 5383
             A        G K + G  G++ P         +G P +   RGP  +GD    G    P
Sbjct: 478  EA--------GPKGEPGPHGIQGP---------IGPPGEEGKRGP--RGDPGTVGP-PGP 517

Query: 5384 KVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLK 5443
                GAP        GS  LP  K  Q      G    V + GP+ S    G   +  L 
Sbjct: 518  VGERGAP--GNRGFPGSDGLPGPKGAQ------GERGPVGSSGPKGSQGDPGRPGEPGLP 569

Query: 5444 GPRISAPNVDFNLEGPKVK-GSLGATGEIKGPTVGGGLPG-IGVQGLEGNLQMPGIKSSG 5501
            G R    N    ++GP+ K G LGA GE   P    G PG IG++G  G++ +PG K S 
Sbjct: 570  GARGLTGNP--GVQGPEGKLGPLGAPGEDGRP----GPPGSIGIRGQPGSMGLPGPKGSS 623

Query: 5502 CDVNLPGV--NVKLPTGQISGPEIKGGLKGS-EVGFHGAAPDISVKGPAFNMASPESDFG 5558
             D   PG   N  +P GQ   P   G +  S  VG  G A +   +GP      P    G
Sbjct: 624  GDPGKPGEAGNAGVP-GQRGAPGKDGEVGPSGPVGPPGLAGERGEQGP----PGPTGFQG 678

Query: 5559 I-NLKGPKIKGGADVSGGVSAPDISLGE-GHLSVKGSGGEWKGPQVSSALNLDTSKFAGG 5616
            +    GP  +GG     GV     ++G  G    +G+ GE   P ++          AGG
Sbjct: 679  LPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPG--EKGMAGG 736

Query: 5617 LHFSGPKVEGGVKGGQIGLQAPGL 5640
                GPK   G  G       PGL
Sbjct: 737  HGPDGPKGSPGPSGTPGDTGPPGL 760



 Score = 38.9 bits (89), Expect = 0.15
 Identities = 101/380 (26%), Positives = 130/380 (34%), Gaps = 59/380 (15%)

Query: 203 KTVIRLPSGSGAASPTGSAVDIRAGAISASGPE----------LQGAGHSKLQVTMPGIK 252
           K  +  P   G A PTG       GA+   GP            QGA   +    MPG K
Sbjct: 311 KGEVGAPGSKGEAGPTGPM-----GAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPG-K 364

Query: 253 VGGSGVNVNAKGLDLGGRGGVQVPAVDISSSLGGRAVE-VQGPSLESGDHGKIKFPTMKV 311
            G  G           G  G++  A       G R  E  QG   E+G  G +  P +  
Sbjct: 365 PGPMGPLGIPGSSGFPGNPGMKGEA----GPTGARGPEGPQGQRGETGPPGPVGSPGLPG 420

Query: 312 PKFGVST-GREGQTPKAGLRVSAPEVSVGHKGGKPGLTIQAPQLEVSVPSANIEGLEGKL 370
                 T G +G T   G   S P  S G  G  PG     PQ      S   +G+ G+ 
Sbjct: 421 AIGTDGTPGAKGPTGSPG--TSGPPGSAGPPGS-PG-----PQ-----GSTGPQGIRGQP 467

Query: 371 KGPQITGPSLEGDLGLKGAKP----QGHIGVDASAPQIGGSITGPSVEVQAPDIDVQGPG 426
             P +  P  +G+ G KG       QG IG      + G      +V    P  +   PG
Sbjct: 468 GDPGV--PGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPG 525

Query: 427 SKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLEGKMKGT 486
           ++       +P     GA+GE   +  + P G    PG  G+  LP     G  G     
Sbjct: 526 NRGFPGSDGLP--GPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLP-----GARGLTGNP 578

Query: 487 KVKTPEMIIQKPKISMQDVDLSLGSPKLKGDIKV-SAPGVQGDVKGPQVALKGSRVDIET 545
            V+ PE      K+         G P   G I +   PG  G + GP    KGS  D   
Sbjct: 579 GVQGPE-----GKLGPLGAPGEDGRPGPPGSIGIRGQPGSMG-LPGP----KGSSGDPGK 628

Query: 546 PNLEGTLTGPRLGSPSGKTG 565
           P   G    P      GK G
Sbjct: 629 PGEAGNAGVPGQRGAPGKDG 648



 Score = 38.9 bits (89), Expect = 0.15
 Identities = 124/484 (25%), Positives = 164/484 (33%), Gaps = 115/484 (23%)

Query: 5206 PKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGD 5265
            P  KGD   +G +G +       A+           G+PG     G A      P+ E  
Sbjct: 773  PGPKGDRGGIGEKGAEGTAGNDGAR-----------GLPGPLGPPGPAG-----PTGEKG 816

Query: 5266 LRGPDVKLEGPDVSLKGPGV---DLPSVNLSMPKVSGPDLDLNLKG----PSLKGDLDAS 5318
              GP   L GP  S   PG    + P+  +      GPD    +KG    P  KGD  + 
Sbjct: 817  EPGPR-GLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSP 875

Query: 5319 VPSMKVHAPGLN-LSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVS 5377
             P     +PG +  +GV G    GG G + P                   P   G    +
Sbjct: 876  GPQGLAGSPGPHGPNGVPGLK--GGRGTQGP-------------------PGATGFPGSA 914

Query: 5378 GDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPG 5437
            G +  P    GAP        G +  P  + P      PGS   V  +GP  +G   GPG
Sbjct: 915  GRVG-PPGPAGAP-----GPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGP--AGPPGGPG 966

Query: 5438 VDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPG-IGVQGLEGNLQMPG 5496
                                    KG  G  G+  GP    G PG  G  G  G + MPG
Sbjct: 967  D-----------------------KGDPGEDGQ-PGPD---GPPGPAGTTGQRGIVGMPG 999

Query: 5497 IKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKG-----SEVGFHGAAPDISVKGPAFNMA 5551
             +    +  +PG+     T    GP    G KG        G +G   +   +GPA N  
Sbjct: 1000 QRG---ERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDG 1056

Query: 5552 SPESDFGINLKGPK-IKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDT 5610
            +P  D  +  +G +   G A + G   AP      G +   G  G+   P   S   +  
Sbjct: 1057 TPGRDGAVGERGDRGDPGPAGLPGSQGAPGT---PGPVGAPGDAGQRGDP--GSRGPIGP 1111

Query: 5611 SKFAGGLHFSGPKVEGGVKG--------------GQIGLQA-PGLSVSGPQGHLESGSGK 5655
               AG     GP+   G KG              G  GLQ  PG    GP G  E GS  
Sbjct: 1112 PGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPG--PPGPNG--EQGSAG 1167

Query: 5656 VTFP 5659
            +  P
Sbjct: 1168 IPGP 1171



 Score = 36.2 bits (82), Expect = 0.99
 Identities = 126/466 (27%), Positives = 163/466 (34%), Gaps = 79/466 (16%)

Query: 5209 KGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGG-----GAEVHAQLPSLE 5263
            KG+    G++GP +   G E K + P+     +G PG   E G     G      LP  +
Sbjct: 482  KGEPGPHGIQGP-IGPPGEEGK-RGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPK 539

Query: 5264 GDL--RGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLK-GDLDASVP 5320
            G    RGP V   GP  S   PG         +P   G   +  ++GP  K G L A   
Sbjct: 540  GAQGERGP-VGSSGPKGSQGDPG---RPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGE 595

Query: 5321 SMKVHAPG-LNLSGVGGKMQVGGDGVKV--PGIDATTKLNVGAPDVTLRG-PSLQGDLAV 5376
              +   PG + + G  G M + G       PG       N G P    RG P   G++  
Sbjct: 596  DGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAG-NAGVPGQ--RGAPGKDGEVGP 652

Query: 5377 SGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQF------GISTPGSDLHVNAKGPQVS 5430
            SG +  P ++    +       G   LP    P            PG    V   GP+  
Sbjct: 653  SGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGE 712

Query: 5431 ----GELKGPGVDVNLKGPRISA----PNVDFNLEGPK----------VKGSLGATGEIK 5472
                GE   PG+   L G +  A    P+      GP           ++G  G  G   
Sbjct: 713  RGNPGERGEPGI-TGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAG 771

Query: 5473 GPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEV 5532
             P   G   GIG +G EG     G +       LPG     P G   GP    G KG E 
Sbjct: 772  TPGPKGDRGGIGEKGAEGTAGNDGAR------GLPG-----PLGP-PGPAGPTGEKG-EP 818

Query: 5533 GFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGEGHLSVKG 5592
            G  G      + GP  +  +P S      +G     GA    G   PD     G   VKG
Sbjct: 819  GPRG------LVGPPGSRGNPGS------RGENGPTGAVGFAGPQGPD-----GQPGVKG 861

Query: 5593 SGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQAP 5638
              GE    Q   A +      AG     GP    G+KGG+ G Q P
Sbjct: 862  EPGE--PGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGR-GTQGP 904



 Score = 35.4 bits (80), Expect = 1.7
 Identities = 68/259 (26%), Positives = 87/259 (33%), Gaps = 41/259 (15%)

Query: 5416 PGSDLHVNAKGPQ-VSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGP 5474
            PGS   V  +GPQ + G+  G G       P    P       GP+  G  G  GE   P
Sbjct: 212  PGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPE--GPPGKPGEDGEP 269

Query: 5475 TVGG--------------GLPGI-GVQGLEGNLQMPGIKSSGCDVNLPGVNVKL-PTGQI 5518
               G              G PG  G+ GL+G+    G++    +V  PG   +  PTG +
Sbjct: 270  GRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPM 329

Query: 5519 S-----GPEIKGGLKG-----SEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKG 5568
                  GP    G +G        G  GA       GP   +  P S       G K + 
Sbjct: 330  GAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEA 389

Query: 5569 GADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGV 5628
            G   + G   P    GE      G  G    P +  A+  D +  A      GP    G 
Sbjct: 390  GPTGARGPEGPQGQRGE-----TGPPGPVGSPGLPGAIGTDGTPGA-----KGPTGSPGT 439

Query: 5629 KGGQIGLQAPGLSVSGPQG 5647
             G       PG    GPQG
Sbjct: 440  SGPPGSAGPPG--SPGPQG 456


>gi|126352608 elastin isoform e precursor [Homo sapiens]
          Length = 705

 Score = 57.0 bits (136), Expect = 5e-07
 Identities = 123/469 (26%), Positives = 163/469 (34%), Gaps = 63/469 (13%)

Query: 5210 GDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPS---LEGDL 5266
            G VP VG  G       P+         +P +G+PGV    GG    A+ P    L G  
Sbjct: 113  GGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGV--YPGGVLPGARFPGVGVLPGVP 170

Query: 5267 RGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKV-- 5324
             G  VK + P V   G    +P V        G  L   +K P L G       + K+  
Sbjct: 171  TGAGVKPKAPGVG--GAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPY 228

Query: 5325 -HAPGLNLSGVGGK------MQVGGDGVKVPGIDATTKLNVGA----PDVTLRG-PSLQG 5372
             + PG  ++G  GK        VG          A  K   GA    P V   G P + G
Sbjct: 229  GYGPG-GVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG 287

Query: 5373 DLAVSGDIK---CPKVSVGAPDLSLEASEGSIKLPKMKLPQFG---ISTPGSDLHVNAKG 5426
             +   G I     P  +  A   +  A  G+        P FG   +  PG+   V   G
Sbjct: 288  AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAG--VPGVG 345

Query: 5427 PQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVG--------- 5477
               +G    PG  +    P  + P V       K        G   G  VG         
Sbjct: 346  VPGAGIPVVPGAGI----PGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGA 401

Query: 5478 GGLP--GIGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFH 5535
            GG P  G+GV G+ G   +PG+        +PGV +  P  Q +    K    G   G  
Sbjct: 402  GGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGIS-PEAQ-AAAAAKAAKYGLVPGV- 458

Query: 5536 GAAPDISVKGPAFNMASPESDFGINL-KGPKIKGGADVSGGVS-APDISLGEGHLSVKGS 5593
            G AP + V  P   +A      G+ L  G  +  G  V+ GV  AP I  G    + K +
Sbjct: 459  GVAPGVGV-APGVGVAP-----GVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSA 512

Query: 5594 GGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQAPGLSV 5642
                   Q+ +A  L       G    G  V  GV G  +G   PGL V
Sbjct: 513  AKVAAKAQLRAAAGL-------GAGIPGLGVGVGVPGLGVGAGVPGLGV 554



 Score = 38.1 bits (87), Expect = 0.26
 Identities = 88/316 (27%), Positives = 126/316 (39%), Gaps = 55/316 (17%)

Query: 5185 PSFG---ISAPQVSIPDVNVNLKGPKIKGDVPSVGLEGPDVD-LQGPEAKIKFP----KF 5236
            P FG   +  P   +P V V   G  +   VP  G+ G  V  +  PEA  K      K+
Sbjct: 327  PGFGPGVVGVPGAGVPGVGVPGAGIPV---VPGAGIPGAAVPGVVSPEAAAKAAAKAAKY 383

Query: 5237 -SMPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVD-LPSVNLSM 5294
             + P +G+ G+   G GA          G   G  V + G       PGV  +P V   +
Sbjct: 384  GARPGVGVGGIPTYGVGA----------GGFPGFGVGVGGIPGVAGVPGVGGVPGVG-GV 432

Query: 5295 PKVS-GPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLS-GVGGKMQVG---GDGVKVPG 5349
            P V   P+        + K  L   VP + V APG+ ++ GVG    VG   G GV  PG
Sbjct: 433  PGVGISPEAQAAAAAKAAKYGL---VPGVGV-APGVGVAPGVGVAPGVGLAPGVGV-APG 487

Query: 5350 IDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEG-SIKLPKMKL 5408
            +     + V AP +   GP   G +A +      KV+  A    L A+ G    +P + +
Sbjct: 488  VGVAPGVGV-APGI---GP---GGVAAAAK-SAAKVAAKA---QLRAAAGLGAGIPGLGV 536

Query: 5409 PQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGAT 5468
               G+  PG  +     G  V   + G G    + G   +A    +   G  V G LG  
Sbjct: 537  ---GVGVPGLGVGAGVPGLGVGAGVPGFGA---VPGALAAAKAAKY---GAAVPGVLGGL 587

Query: 5469 GEIKGPTVGGGLPGIG 5484
            G + G  + GG+ G G
Sbjct: 588  GALGGVGIPGGVVGAG 603



 Score = 38.1 bits (87), Expect = 0.26
 Identities = 84/358 (23%), Positives = 125/358 (34%), Gaps = 68/358 (18%)

Query: 5238 MPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKV 5297
            +P  G+PGV + G G  V             P   + G  V    PGV  P         
Sbjct: 336  VPGAGVPGVGVPGAGIPVV------------PGAGIPGAAV----PGVVSPEAAAKAAAK 379

Query: 5298 S---GPDLDLNLKGPSLKGDLDASVPSMKVHAPGL----NLSGVGGKMQVGGDGVKVPGI 5350
            +   G    + + G    G      P   V   G+     + GVGG   VGG    VPG+
Sbjct: 380  AAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGG----VPGV 435

Query: 5351 DATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQ 5410
              + +    A     +   + G     G    P V V AP + L    G         P 
Sbjct: 436  GISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGV-APGVGLAPGVGVA-------PG 487

Query: 5411 FGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGE 5470
             G++ PG  +      P +     GPG      G   +A +        +++ + G    
Sbjct: 488  VGVA-PGVGV-----APGI-----GPG------GVAAAAKSAAKVAAKAQLRAAAGLGAG 530

Query: 5471 IKGPTVGGGLPGIGV----------QGLEGNLQMPG----IKSSGCDVNLPGVNVKLPTG 5516
            I G  VG G+PG+GV           G+ G   +PG     K++     +PGV   L  G
Sbjct: 531  IPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGL--G 588

Query: 5517 QISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSG 5574
             + G  I GG+ G+      AA   + K   F +       G+ + G  + G   + G
Sbjct: 589  ALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGG 646


>gi|126352700 elastin isoform b precursor [Homo sapiens]
          Length = 677

 Score = 57.0 bits (136), Expect = 5e-07
 Identities = 123/469 (26%), Positives = 163/469 (34%), Gaps = 63/469 (13%)

Query: 5210 GDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPS---LEGDL 5266
            G VP VG  G       P+         +P +G+PGV    GG    A+ P    L G  
Sbjct: 103  GGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGV--YPGGVLPGARFPGVGVLPGVP 160

Query: 5267 RGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKV-- 5324
             G  VK + P V   G    +P V        G  L   +K P L G       + K+  
Sbjct: 161  TGAGVKPKAPGVG--GAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPY 218

Query: 5325 -HAPGLNLSGVGGK------MQVGGDGVKVPGIDATTKLNVGA----PDVTLRG-PSLQG 5372
             + PG  ++G  GK        VG          A  K   GA    P V   G P + G
Sbjct: 219  GYGPG-GVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG 277

Query: 5373 DLAVSGDIK---CPKVSVGAPDLSLEASEGSIKLPKMKLPQFG---ISTPGSDLHVNAKG 5426
             +   G I     P  +  A   +  A  G+        P FG   +  PG+   V   G
Sbjct: 278  AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAG--VPGVG 335

Query: 5427 PQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVG--------- 5477
               +G    PG  +    P  + P V       K        G   G  VG         
Sbjct: 336  VPGAGIPVVPGAGI----PGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGA 391

Query: 5478 GGLP--GIGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFH 5535
            GG P  G+GV G+ G   +PG+        +PGV +  P  Q +    K    G   G  
Sbjct: 392  GGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGIS-PEAQ-AAAAAKAAKYGLVPGV- 448

Query: 5536 GAAPDISVKGPAFNMASPESDFGINL-KGPKIKGGADVSGGVS-APDISLGEGHLSVKGS 5593
            G AP + V  P   +A      G+ L  G  +  G  V+ GV  AP I  G    + K +
Sbjct: 449  GVAPGVGV-APGVGVAP-----GVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSA 502

Query: 5594 GGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQAPGLSV 5642
                   Q+ +A  L       G    G  V  GV G  +G   PGL V
Sbjct: 503  AKVAAKAQLRAAAGL-------GAGIPGLGVGVGVPGLGVGAGVPGLGV 544



 Score = 38.1 bits (87), Expect = 0.26
 Identities = 88/316 (27%), Positives = 126/316 (39%), Gaps = 55/316 (17%)

Query: 5185 PSFG---ISAPQVSIPDVNVNLKGPKIKGDVPSVGLEGPDVD-LQGPEAKIKFP----KF 5236
            P FG   +  P   +P V V   G  +   VP  G+ G  V  +  PEA  K      K+
Sbjct: 317  PGFGPGVVGVPGAGVPGVGVPGAGIPV---VPGAGIPGAAVPGVVSPEAAAKAAAKAAKY 373

Query: 5237 -SMPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVD-LPSVNLSM 5294
             + P +G+ G+   G GA          G   G  V + G       PGV  +P V   +
Sbjct: 374  GARPGVGVGGIPTYGVGA----------GGFPGFGVGVGGIPGVAGVPGVGGVPGVG-GV 422

Query: 5295 PKVS-GPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLS-GVGGKMQVG---GDGVKVPG 5349
            P V   P+        + K  L   VP + V APG+ ++ GVG    VG   G GV  PG
Sbjct: 423  PGVGISPEAQAAAAAKAAKYGL---VPGVGV-APGVGVAPGVGVAPGVGLAPGVGV-APG 477

Query: 5350 IDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEG-SIKLPKMKL 5408
            +     + V AP +   GP   G +A +      KV+  A    L A+ G    +P + +
Sbjct: 478  VGVAPGVGV-APGI---GP---GGVAAAAK-SAAKVAAKA---QLRAAAGLGAGIPGLGV 526

Query: 5409 PQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGAT 5468
               G+  PG  +     G  V   + G G    + G   +A    +   G  V G LG  
Sbjct: 527  ---GVGVPGLGVGAGVPGLGVGAGVPGFGA---VPGALAAAKAAKY---GAAVPGVLGGL 577

Query: 5469 GEIKGPTVGGGLPGIG 5484
            G + G  + GG+ G G
Sbjct: 578  GALGGVGIPGGVVGAG 593



 Score = 38.1 bits (87), Expect = 0.26
 Identities = 84/358 (23%), Positives = 125/358 (34%), Gaps = 68/358 (18%)

Query: 5238 MPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKV 5297
            +P  G+PGV + G G  V             P   + G  V    PGV  P         
Sbjct: 326  VPGAGVPGVGVPGAGIPVV------------PGAGIPGAAV----PGVVSPEAAAKAAAK 369

Query: 5298 S---GPDLDLNLKGPSLKGDLDASVPSMKVHAPGL----NLSGVGGKMQVGGDGVKVPGI 5350
            +   G    + + G    G      P   V   G+     + GVGG   VGG    VPG+
Sbjct: 370  AAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGG----VPGV 425

Query: 5351 DATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQ 5410
              + +    A     +   + G     G    P V V AP + L    G         P 
Sbjct: 426  GISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGV-APGVGLAPGVGVA-------PG 477

Query: 5411 FGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGE 5470
             G++ PG  +      P +     GPG      G   +A +        +++ + G    
Sbjct: 478  VGVA-PGVGV-----APGI-----GPG------GVAAAAKSAAKVAAKAQLRAAAGLGAG 520

Query: 5471 IKGPTVGGGLPGIGV----------QGLEGNLQMPG----IKSSGCDVNLPGVNVKLPTG 5516
            I G  VG G+PG+GV           G+ G   +PG     K++     +PGV   L  G
Sbjct: 521  IPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGL--G 578

Query: 5517 QISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSG 5574
             + G  I GG+ G+      AA   + K   F +       G+ + G  + G   + G
Sbjct: 579  ALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGG 636


>gi|126352440 elastin isoform a precursor [Homo sapiens]
          Length = 724

 Score = 56.6 bits (135), Expect = 7e-07
 Identities = 123/485 (25%), Positives = 165/485 (34%), Gaps = 76/485 (15%)

Query: 5210 GDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPS---LEGDL 5266
            G VP VG  G       P+         +P +G+PGV    GG    A+ P    L G  
Sbjct: 113  GGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGV--YPGGVLPGARFPGVGVLPGVP 170

Query: 5267 RGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKV-- 5324
             G  VK + P V   G    +P V        G  L   +K P L G       + K+  
Sbjct: 171  TGAGVKPKAPGVG--GAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPY 228

Query: 5325 -HAPGLNLSGVGGK------MQVGGDGVKVPGIDATTKLNVGA----PDVTLRG-PSLQG 5372
             + PG  ++G  GK        VG          A  K   GA    P V   G P + G
Sbjct: 229  GYGPG-GVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG 287

Query: 5373 DLAVSGDIK---CPKVSVGAPDLSLEASEGSIKLPKMKLPQFG---ISTPGSDLHVNAKG 5426
             +   G I     P  +  A   +  A  G+        P FG   +  PG+   V   G
Sbjct: 288  AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAG--VPGVG 345

Query: 5427 PQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVG--------- 5477
               +G    PG  +    P  + P V       K        G   G  VG         
Sbjct: 346  VPGAGIPVVPGAGI----PGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGA 401

Query: 5478 GGLP--GIGVQGLEGNLQMPGIKSSGCDVNLPGVNV-------------KLPTGQISGPE 5522
            GG P  G+GV G+ G   +PG+        +PGV +             K   G  +   
Sbjct: 402  GGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAA 461

Query: 5523 IKGGLKGSEVGF---HGAAPDISVKGPAFNMASPESDFGINL-KGPKIKGGADVSGGVS- 5577
             K   K ++ G     G AP + V  P   +A      G+ L  G  +  G  V+ GV  
Sbjct: 462  AKAAAKAAQFGLVPGVGVAPGVGV-APGVGVAP-----GVGLAPGVGVAPGVGVAPGVGV 515

Query: 5578 APDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQA 5637
            AP I  G    + K +       Q+ +A  L       G    G  V  GV G  +G   
Sbjct: 516  APGIGPGGVAAAAKSAAKVAAKAQLRAAAGL-------GAGIPGLGVGVGVPGLGVGAGV 568

Query: 5638 PGLSV 5642
            PGL V
Sbjct: 569  PGLGV 573



 Score = 42.4 bits (98), Expect = 0.014
 Identities = 84/371 (22%), Positives = 131/371 (35%), Gaps = 75/371 (20%)

Query: 5238 MPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKV 5297
            +P  G+PGV + G G  V                           PG  +P    ++P V
Sbjct: 336  VPGAGVPGVGVPGAGIPVV--------------------------PGAGIPGA--AVPGV 367

Query: 5298 SGPDLDLNLKGPSLK-----GDLDASVPSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDA 5352
              P+        + K     G     +P+  V A G    GVG    VGG    +PG+  
Sbjct: 368  VSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVG----VGG----IPGVAG 419

Query: 5353 TTKLNVGAPDVT-LRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKL--- 5408
               +  G P V  + G  +  +   +   K  K  VG P  +  A++ + K  +  L   
Sbjct: 420  VPGVG-GVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTP--AAAAAKAAAKAAQFGLVPG 476

Query: 5409 ----PQFGIS-----TPGSDLHVNAKGPQVSGELKGPGV--DVNLKGPRISAPNVDFNLE 5457
                P  G++      PG  L          G   G GV   +   G   +A +      
Sbjct: 477  VGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAA 536

Query: 5458 GPKVKGSLGATGEIKGPTVGGGLPGIGV----------QGLEGNLQMPG----IKSSGCD 5503
              +++ + G    I G  VG G+PG+GV           G+ G   +PG     K++   
Sbjct: 537  KAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYG 596

Query: 5504 VNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKG 5563
              +PGV   L  G + G  I GG+ G+      AA   + K   F +       G+ + G
Sbjct: 597  AAVPGVLGGL--GALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGG 654

Query: 5564 PKIKGGADVSG 5574
              + G   + G
Sbjct: 655  LGVPGVGGLGG 665


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
            sapiens]
          Length = 1424

 Score = 56.6 bits (135), Expect = 7e-07
 Identities = 141/553 (25%), Positives = 191/553 (34%), Gaps = 92/553 (16%)

Query: 5156 EGDLKGPKVQANLGAPDI-NIEGLDAKVKTPSFGISAPQVSIPDVNVNLKG-PKIKGDVP 5213
            +G+   P +   LG P I    GL  +   P+           D+ ++ KG P + G   
Sbjct: 129  KGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPA--------KEEDIELDAKGDPGLPGAPG 180

Query: 5214 SVGLEGPD-----VDLQGPEAKIKFPKFSMPK-------------IGIPGVK-MEGGGAE 5254
              GL GP      V   GP     FP    P+              G  GVK + G    
Sbjct: 181  PQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGP 240

Query: 5255 VHAQLPSLEGDLRGPDVKLEGPDVSLKG-PGVDLPS--VNLSMPKVSGPDLDLNLKGPSL 5311
                + +L G     D+K E  D    G PG   PS     S     G   D  L+G   
Sbjct: 241  PGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPG 300

Query: 5312 KGDLDASVPSMKVHA----PGL-NLSGVGG-KMQVGGDGVKVPGIDATTKLNVGAPDVTL 5365
            K  +     S  V      PGL    G+ G K  +G  G + P     T    G  + T 
Sbjct: 301  KDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKG-DEGTP 359

Query: 5366 RGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAK 5425
              P  +G     G    P V  G+P  S     G+   P +K  +     PG D      
Sbjct: 360  GPPGPRGARGPQGPSGPPGVP-GSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPG 418

Query: 5426 GPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEI---KGPTVGGGLPG 5482
             P  +G    PG+                    P   G  G  G+I   KGP    GLPG
Sbjct: 419  SPGCAGS---PGL--------------------PGSPGPPGPPGDIVFRKGPPGDHGLPG 455

Query: 5483 I----GVQGLEGNLQMPGIKSSGCDV-----NLPGVNVKLPTGQISGPEIKGGLKGSE-- 5531
                 G+ G++G    PG+  + C        LPG+        I G +   GLKGS   
Sbjct: 456  YLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGS 515

Query: 5532 ---------VGFHGAAPDISVKGPAFNMASPESDFGI----NLKG-PKIKGGADVSGGVS 5577
                      GF GA  D  +KG       PE   G+     L+G P  KG   + G   
Sbjct: 516  PGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG 575

Query: 5578 APDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQA 5637
               +   +G L++ G  G+   P    +          G    GP+ E G++G Q    A
Sbjct: 576  VKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA 635

Query: 5638 PG-LSVSGPQGHL 5649
            PG    +GP+G L
Sbjct: 636  PGPPGEAGPRGEL 648



 Score = 48.9 bits (115), Expect = 1e-04
 Identities = 117/478 (24%), Positives = 164/478 (34%), Gaps = 96/478 (20%)

Query: 5203 LKGPKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSL 5262
            L GP  +  +P +G  GP     GP+    FP  +   +G PG KM   G      LP  
Sbjct: 687  LPGPDGEPGIPGIGFPGPP----GPKGDQGFPG-TKGSLGCPG-KMGEPGLPGKPGLPGA 740

Query: 5263 EGDLRGPDVKLEGPDVSLKGPG----------VDLPSVNLSMPKVSGPDLDLNLKGPSLK 5312
            +G+   P V + G   +   PG          + LP     +P + G   +  L GP  +
Sbjct: 741  KGE---PAVAMPGGPGTPGFPGERGNSGEHGEIGLPG----LPGLPGTPGNEGLDGP--R 791

Query: 5313 GDLDASVPSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQG 5372
            GD     P  +   PG  + G  G   +       PG++             L+G   QG
Sbjct: 792  GDPGQPGPPGEQGPPGRCIEGPRGAQGL-------PGLNG------------LKGQ--QG 830

Query: 5373 DLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGE 5432
                +G    PK   G P L      G               +PG   H    GP   G+
Sbjct: 831  RRGKTG----PKGDPGIPGLDRSGFPGET------------GSPGIPGHQGEMGPL--GQ 872

Query: 5433 LKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNL 5492
               PG +  + GP    P  D  +      G++G  G    P   G     G+ G++G  
Sbjct: 873  RGYPG-NPGILGP----PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQR 927

Query: 5493 QMPGIKSSGCDVNLPGVN-VKLPTGQISGPEIKG-----GLKGSE--VGFHGAAPDISVK 5544
              PG K    D   PG + +    G    P +KG     G KG+    G  G      + 
Sbjct: 928  GTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLP 987

Query: 5545 GPAFNMASPESDFGI--NLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQV 5602
            GPA     P  D G   N   P ++G     G +  P      G L   G  G    P +
Sbjct: 988  GPA-GPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGR---PGL 1043

Query: 5603 SSALNLDTSKFAGGLHFS------GPKVEGGVKG-----GQIGLQAP--GLSVSGPQG 5647
                 L   K   G          GP  + G+ G     G++G   P   L  +GP+G
Sbjct: 1044 PGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEG 1101



 Score = 42.0 bits (97), Expect = 0.018
 Identities = 127/484 (26%), Positives = 169/484 (34%), Gaps = 103/484 (21%)

Query: 5206 PKIKGDVPSVGLEGPDVDLQGP-EAKIKFPKFSMPKIGIPGVKMEGG--GAEVHAQLPSL 5262
            P +KG   + G +G   D   P  ++I      +   G PG+K   G  G + +  +P +
Sbjct: 921  PGVKGQRGTPGAKGEQGDKGNPGPSEISHV---IGDKGEPGLKGFAGNPGEKGNRGVPGM 977

Query: 5263 EG--DLRGPDVKLEGPDVSLKGPGVDLPSV-NLSMPKVSG-PDLDLNLKGPSLKGDLDAS 5318
             G   L+G    L GP     GP  DL S  N   P + G P    N+  P  KG     
Sbjct: 978  PGLKGLKG----LPGP-AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTL 1032

Query: 5319 VPSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSG 5378
                +   PGL   G+ G     G+    PG    T+   G P  T   P L GD+   G
Sbjct: 1033 GFPGRAGRPGL--PGIHGLQGDKGE----PGYSEGTR--PGPPGPT-GDPGLPGDMGKKG 1083

Query: 5379 DIKCPKV--------------SVGAP----------DLSLEASEGSIKLPKMKLPQFGIS 5414
            ++  P                S G+P          DL  +  +G +  P ++ P     
Sbjct: 1084 EMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPG 1143

Query: 5415 TPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGP 5474
             PGS   +  +G Q    + GP  +    G   + P    N      KG  GA G     
Sbjct: 1144 FPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPG----- 1198

Query: 5475 TVGGGLPG-IGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKG-------- 5525
                GLPG  G  G  G     GI+       LPG  +   TG    P  +G        
Sbjct: 1199 --FPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPP 1256

Query: 5526 GLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGE 5585
            G  GS V        I +KG   +M  P         GP  KG    +G +  P      
Sbjct: 1257 GPPGSHV--------IGIKGDKGSMGHP---------GP--KGPPGTAGDMGPP------ 1291

Query: 5586 GHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKG--GQIGLQAPGLSVS 5643
            G L   G+ G   GP+           F G   F G K E G  G  G IG   P +   
Sbjct: 1292 GRLGAPGTPG-LPGPRGDPG-------FQG---FPGVKGEKGNPGFLGSIGPPGP-IGPK 1339

Query: 5644 GPQG 5647
            GP G
Sbjct: 1340 GPPG 1343



 Score = 41.6 bits (96), Expect = 0.024
 Identities = 92/347 (26%), Positives = 129/347 (37%), Gaps = 50/347 (14%)

Query: 5200 NVNLKG-PKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGG--GAEVH 5256
            N  L G P   G     GL+G   +   PE ++  P       G PG++ + G  G +  
Sbjct: 518  NTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVP-------GDPGLRGQPGRKGLDGI 570

Query: 5257 AQLPSLEGDLRGPDVKL--------EGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKG 5308
               P ++G L GP  +L        +GP      PG   P+     P   GP  +  L+G
Sbjct: 571  PGTPGVKG-LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGY-GPQGEPGLQG 628

Query: 5309 PSLKGDLDASVPSMKVHAPGL-NLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRG 5367
                      VP     APG    +G  G++ V      VPG         G P      
Sbjct: 629  TQ-------GVPG----APGPPGEAGPRGELSVS---TPVPGPPGPP----GPPG----H 666

Query: 5368 PSLQGDLAVSGDI-KCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKG 5426
            P  QG   + G + KC    +  PD   E     I  P    P+     PG+   +   G
Sbjct: 667  PGPQGPPGIPGSLGKCGDPGLPGPDG--EPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPG 724

Query: 5427 PQVSGELKG-PGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGI-G 5484
                  L G PG+      P ++ P        P  +G+ G  GEI  P + G LPG  G
Sbjct: 725  KMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPG-LPGTPG 783

Query: 5485 VQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSE 5531
             +GL+G    PG      +   PG  ++ P G    P +  GLKG +
Sbjct: 784  NEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGL-NGLKGQQ 829



 Score = 36.2 bits (82), Expect = 0.99
 Identities = 91/341 (26%), Positives = 116/341 (34%), Gaps = 48/341 (14%)

Query: 5241 IGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLS------M 5294
            +G+PG      G++     P L G L  P +         KG       + L       +
Sbjct: 120  VGVPGCS----GSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGL 175

Query: 5295 PKVSGPDLDLNLKGP-SLKGDLDASVPSMKVHAPG-LNLSGVGGKM------QVGGDGVK 5346
            P   GP     L GP    G +    P      PG +   G  G M        G  GVK
Sbjct: 176  PGAPGPQ---GLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVK 232

Query: 5347 ----VPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIK 5402
                 PG   T  + +  PD        +GD    G+   P  S G P  S  + +G+  
Sbjct: 233  GLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPS-GLPGESYGSEKGAPG 291

Query: 5403 LPKMKLPQFGISTPGSDLHVNAKG----PQVSGE--LKGPGVDVNLKGPRISAPNVDFNL 5456
             P ++        PG       KG    P + GE  +KG   D+   G R      D   
Sbjct: 292  DPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQ 351

Query: 5457 EG--------PKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPG 5508
            E         P  +G+ G  G   GP    G PG    GL G    PG+K S  +   PG
Sbjct: 352  EKGDEGTPGPPGPRGARGPQGP-SGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG 410

Query: 5509 VNVKLPTGQISGPEIKG--GLKGSEVGFHGAAPDISV-KGP 5546
               K   G    P   G  GL GS  G  G   DI   KGP
Sbjct: 411  ---KDAMGTPGSPGCAGSPGLPGSP-GPPGPPGDIVFRKGP 447



 Score = 35.0 bits (79), Expect = 2.2
 Identities = 58/220 (26%), Positives = 83/220 (37%), Gaps = 41/220 (18%)

Query: 267 LGGRGGVQVPAVDISSSLGGRAVEVQGPSLESGDHGKIKFPTMKVPKFGVSTGREGQTPK 326
           LG  G   +P  D    + G  +   GP    GD G   FP  K      S G  G+  +
Sbjct: 679 LGKCGDPGLPGPDGEPGIPG--IGFPGPPGPKGDQG---FPGTKG-----SLGCPGKMGE 728

Query: 327 AGLRVSAPEVSVGHKGGKPGLTIQAPQLEVSVPSANIEGLEGKLKGPQITGPSLE-GDLG 385
            GL             GKPGL     +  V++P     G  G    P   G S E G++G
Sbjct: 729 PGLP------------GKPGLPGAKGEPAVAMP-----GGPGTPGFPGERGNSGEHGEIG 771

Query: 386 LKGAK----PQGHIGVDASAPQIGGSITGPSVEVQAPDIDVQGPGSKLNVPKMKVPKFSV 441
           L G        G+ G+D   P+      GP  E   P   ++GP     +P        +
Sbjct: 772 LPGLPGLPGTPGNEGLDG--PRGDPGQPGPPGEQGPPGRCIEGPRGAQGLP-------GL 822

Query: 442 SGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLEG 481
           +G KG++     T P G+  +PG+       E  + G+ G
Sbjct: 823 NGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPG 862



 Score = 34.3 bits (77), Expect = 3.8
 Identities = 116/441 (26%), Positives = 153/441 (34%), Gaps = 65/441 (14%)

Query: 5156 EGDLKG-PKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPS 5214
            E  L+G P    N+G P     G   K  T  F   A +  +P ++  L+G K +     
Sbjct: 1007 EPGLRGIPGSMGNMGMP-----GSKGKRGTLGFPGRAGRPGLPGIH-GLQGDKGEPGYSE 1060

Query: 5215 VGLEGP-----DVDLQGPEAKIKFPKFSMPKIGIPGVKMEGG--GAEVHAQLPSLEGDLR 5267
                GP     D  L G   K    K  M + G PG     G  GA      P L G   
Sbjct: 1061 GTRPGPPGPTGDPGLPGDMGK----KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK-P 1115

Query: 5268 GP--DVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVH 5325
            GP  D+  +G    L  PG+  P      P   GP   + ++G   +  +    P+ +  
Sbjct: 1116 GPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP---MGIRGDQGRDGIPG--PAGEKG 1170

Query: 5326 APGLNLSGVGGKMQVGGDGVK----VPGIDATTKLNVGAPDVTLRGPS----LQGDLAVS 5377
              GL  +  G +   G  G K     PG            D   RGP+      G   + 
Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230

Query: 5378 GDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQ----FGIS-TPGSDLHVNAKGPQVSGE 5432
            G I   +     P      S GS   P    P      GI    GS  H   KGP  +  
Sbjct: 1231 GAIIPGQTGNRGPP----GSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG 1286

Query: 5433 LKGPGVDVNLKG-PRISAPNVDFNLEG-PKVKGSLGATGEI-----KGPTVGGGLPGIGV 5485
              GP   +   G P +  P  D   +G P VKG  G  G +      GP    G PG  V
Sbjct: 1287 DMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG--V 1344

Query: 5486 QGLEGNLQMPGIKSSGCDVNLPG-------VNVKLPTGQIS--GPEIKGGLKGSEVGFHG 5536
            +G  G L++  +  S      PG            P G +   GP  K G K  + G  G
Sbjct: 1345 RGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPG-KDGKPGTPG 1403

Query: 5537 AAPDISVKGPAFNMASPESDF 5557
             A +   KG   +   PES F
Sbjct: 1404 PAGE---KGNKGSKGEPESLF 1421



 Score = 33.9 bits (76), Expect = 4.9
 Identities = 71/288 (24%), Positives = 100/288 (34%), Gaps = 60/288 (20%)

Query: 2535 PKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPKISMPDFDLHLKG---- 2590
            PK ++ +SG K D        +GP G    P    P      P    P  +  L+G    
Sbjct: 582  PKGELALSGEKGD--------QGPPGDPGSPGSPGPAGPAGPPGYG-PQGEPGLQGTQGV 632

Query: 2591 PKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKMPKVKMPKFSMPG 2650
            P   G    + P+ E  +  P     GP      P  G QGP                PG
Sbjct: 633  PGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHP--GPQGP----------------PG 674

Query: 2651 FKGE-GPDGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKLKGPKFKMPEMNIKAP-KIS 2708
              G  G  GD  LP  D +   P +   GP     GP+G    P  K    ++  P K+ 
Sbjct: 675  IPGSLGKCGDPGLPGPDGEPGIPGIGFPGPP----GPKGDQGFPGTKG---SLGCPGKMG 727

Query: 2709 MPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPK 2768
             P +      P  KG+  V++P   G           P    +  +   HG        +
Sbjct: 728  EPGLPGKPGLPGAKGEPAVAMPGGPGT----------PGFPGERGNSGEHG--------E 769

Query: 2769 IKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGPEG 2816
            I +P   +PG  G   +  ++ P+ D    GP  +   P   IEGP G
Sbjct: 770  IGLP--GLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRG 815


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
            sapiens]
          Length = 1494

 Score = 56.6 bits (135), Expect = 7e-07
 Identities = 141/553 (25%), Positives = 191/553 (34%), Gaps = 92/553 (16%)

Query: 5156 EGDLKGPKVQANLGAPDI-NIEGLDAKVKTPSFGISAPQVSIPDVNVNLKG-PKIKGDVP 5213
            +G+   P +   LG P I    GL  +   P+           D+ ++ KG P + G   
Sbjct: 129  KGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPA--------KEEDIELDAKGDPGLPGAPG 180

Query: 5214 SVGLEGPD-----VDLQGPEAKIKFPKFSMPK-------------IGIPGVK-MEGGGAE 5254
              GL GP      V   GP     FP    P+              G  GVK + G    
Sbjct: 181  PQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGP 240

Query: 5255 VHAQLPSLEGDLRGPDVKLEGPDVSLKG-PGVDLPS--VNLSMPKVSGPDLDLNLKGPSL 5311
                + +L G     D+K E  D    G PG   PS     S     G   D  L+G   
Sbjct: 241  PGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPG 300

Query: 5312 KGDLDASVPSMKVHA----PGL-NLSGVGG-KMQVGGDGVKVPGIDATTKLNVGAPDVTL 5365
            K  +     S  V      PGL    G+ G K  +G  G + P     T    G  + T 
Sbjct: 301  KDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKG-DEGTP 359

Query: 5366 RGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAK 5425
              P  +G     G    P V  G+P  S     G+   P +K  +     PG D      
Sbjct: 360  GPPGPRGARGPQGPSGPPGVP-GSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPG 418

Query: 5426 GPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEI---KGPTVGGGLPG 5482
             P  +G    PG+                    P   G  G  G+I   KGP    GLPG
Sbjct: 419  SPGCAGS---PGL--------------------PGSPGPPGPPGDIVFRKGPPGDHGLPG 455

Query: 5483 I----GVQGLEGNLQMPGIKSSGCDV-----NLPGVNVKLPTGQISGPEIKGGLKGSE-- 5531
                 G+ G++G    PG+  + C        LPG+        I G +   GLKGS   
Sbjct: 456  YLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGS 515

Query: 5532 ---------VGFHGAAPDISVKGPAFNMASPESDFGI----NLKG-PKIKGGADVSGGVS 5577
                      GF GA  D  +KG       PE   G+     L+G P  KG   + G   
Sbjct: 516  PGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG 575

Query: 5578 APDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQA 5637
               +   +G L++ G  G+   P    +          G    GP+ E G++G Q    A
Sbjct: 576  VKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA 635

Query: 5638 PG-LSVSGPQGHL 5649
            PG    +GP+G L
Sbjct: 636  PGPPGEAGPRGEL 648



 Score = 48.9 bits (115), Expect = 1e-04
 Identities = 117/478 (24%), Positives = 164/478 (34%), Gaps = 96/478 (20%)

Query: 5203 LKGPKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSL 5262
            L GP  +  +P +G  GP     GP+    FP  +   +G PG KM   G      LP  
Sbjct: 687  LPGPDGEPGIPGIGFPGPP----GPKGDQGFPG-TKGSLGCPG-KMGEPGLPGKPGLPGA 740

Query: 5263 EGDLRGPDVKLEGPDVSLKGPG----------VDLPSVNLSMPKVSGPDLDLNLKGPSLK 5312
            +G+   P V + G   +   PG          + LP     +P + G   +  L GP  +
Sbjct: 741  KGE---PAVAMPGGPGTPGFPGERGNSGEHGEIGLPG----LPGLPGTPGNEGLDGP--R 791

Query: 5313 GDLDASVPSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQG 5372
            GD     P  +   PG  + G  G   +       PG++             L+G   QG
Sbjct: 792  GDPGQPGPPGEQGPPGRCIEGPRGAQGL-------PGLNG------------LKGQ--QG 830

Query: 5373 DLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGE 5432
                +G    PK   G P L      G               +PG   H    GP   G+
Sbjct: 831  RRGKTG----PKGDPGIPGLDRSGFPGET------------GSPGIPGHQGEMGPL--GQ 872

Query: 5433 LKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNL 5492
               PG +  + GP    P  D  +      G++G  G    P   G     G+ G++G  
Sbjct: 873  RGYPG-NPGILGP----PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQR 927

Query: 5493 QMPGIKSSGCDVNLPGVN-VKLPTGQISGPEIKG-----GLKGSE--VGFHGAAPDISVK 5544
              PG K    D   PG + +    G    P +KG     G KG+    G  G      + 
Sbjct: 928  GTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLP 987

Query: 5545 GPAFNMASPESDFGI--NLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQV 5602
            GPA     P  D G   N   P ++G     G +  P      G L   G  G    P +
Sbjct: 988  GPA-GPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGR---PGL 1043

Query: 5603 SSALNLDTSKFAGGLHFS------GPKVEGGVKG-----GQIGLQAP--GLSVSGPQG 5647
                 L   K   G          GP  + G+ G     G++G   P   L  +GP+G
Sbjct: 1044 PGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEG 1101



 Score = 42.0 bits (97), Expect = 0.018
 Identities = 127/484 (26%), Positives = 169/484 (34%), Gaps = 103/484 (21%)

Query: 5206 PKIKGDVPSVGLEGPDVDLQGP-EAKIKFPKFSMPKIGIPGVKMEGG--GAEVHAQLPSL 5262
            P +KG   + G +G   D   P  ++I      +   G PG+K   G  G + +  +P +
Sbjct: 921  PGVKGQRGTPGAKGEQGDKGNPGPSEISHV---IGDKGEPGLKGFAGNPGEKGNRGVPGM 977

Query: 5263 EG--DLRGPDVKLEGPDVSLKGPGVDLPSV-NLSMPKVSG-PDLDLNLKGPSLKGDLDAS 5318
             G   L+G    L GP     GP  DL S  N   P + G P    N+  P  KG     
Sbjct: 978  PGLKGLKG----LPGP-AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTL 1032

Query: 5319 VPSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSG 5378
                +   PGL   G+ G     G+    PG    T+   G P  T   P L GD+   G
Sbjct: 1033 GFPGRAGRPGL--PGIHGLQGDKGE----PGYSEGTR--PGPPGPT-GDPGLPGDMGKKG 1083

Query: 5379 DIKCPKV--------------SVGAP----------DLSLEASEGSIKLPKMKLPQFGIS 5414
            ++  P                S G+P          DL  +  +G +  P ++ P     
Sbjct: 1084 EMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPG 1143

Query: 5415 TPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGP 5474
             PGS   +  +G Q    + GP  +    G   + P    N      KG  GA G     
Sbjct: 1144 FPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPG----- 1198

Query: 5475 TVGGGLPG-IGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKG-------- 5525
                GLPG  G  G  G     GI+       LPG  +   TG    P  +G        
Sbjct: 1199 --FPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPP 1256

Query: 5526 GLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGE 5585
            G  GS V        I +KG   +M  P         GP  KG    +G +  P      
Sbjct: 1257 GPPGSHV--------IGIKGDKGSMGHP---------GP--KGPPGTAGDMGPP------ 1291

Query: 5586 GHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKG--GQIGLQAPGLSVS 5643
            G L   G+ G   GP+           F G   F G K E G  G  G IG   P +   
Sbjct: 1292 GRLGAPGTPG-LPGPRGDPG-------FQG---FPGVKGEKGNPGFLGSIGPPGP-IGPK 1339

Query: 5644 GPQG 5647
            GP G
Sbjct: 1340 GPPG 1343



 Score = 41.6 bits (96), Expect = 0.024
 Identities = 92/347 (26%), Positives = 129/347 (37%), Gaps = 50/347 (14%)

Query: 5200 NVNLKG-PKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGG--GAEVH 5256
            N  L G P   G     GL+G   +   PE ++  P       G PG++ + G  G +  
Sbjct: 518  NTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVP-------GDPGLRGQPGRKGLDGI 570

Query: 5257 AQLPSLEGDLRGPDVKL--------EGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKG 5308
               P ++G L GP  +L        +GP      PG   P+     P   GP  +  L+G
Sbjct: 571  PGTPGVKG-LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGY-GPQGEPGLQG 628

Query: 5309 PSLKGDLDASVPSMKVHAPGL-NLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRG 5367
                      VP     APG    +G  G++ V      VPG         G P      
Sbjct: 629  TQ-------GVPG----APGPPGEAGPRGELSVS---TPVPGPPGPP----GPPG----H 666

Query: 5368 PSLQGDLAVSGDI-KCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKG 5426
            P  QG   + G + KC    +  PD   E     I  P    P+     PG+   +   G
Sbjct: 667  PGPQGPPGIPGSLGKCGDPGLPGPDG--EPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPG 724

Query: 5427 PQVSGELKG-PGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGI-G 5484
                  L G PG+      P ++ P        P  +G+ G  GEI  P + G LPG  G
Sbjct: 725  KMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPG-LPGTPG 783

Query: 5485 VQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSE 5531
             +GL+G    PG      +   PG  ++ P G    P +  GLKG +
Sbjct: 784  NEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGL-NGLKGQQ 829



 Score = 36.2 bits (82), Expect = 0.99
 Identities = 91/341 (26%), Positives = 116/341 (34%), Gaps = 48/341 (14%)

Query: 5241 IGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLS------M 5294
            +G+PG      G++     P L G L  P +         KG       + L       +
Sbjct: 120  VGVPGCS----GSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGL 175

Query: 5295 PKVSGPDLDLNLKGP-SLKGDLDASVPSMKVHAPG-LNLSGVGGKM------QVGGDGVK 5346
            P   GP     L GP    G +    P      PG +   G  G M        G  GVK
Sbjct: 176  PGAPGPQ---GLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVK 232

Query: 5347 ----VPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIK 5402
                 PG   T  + +  PD        +GD    G+   P  S G P  S  + +G+  
Sbjct: 233  GLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPS-GLPGESYGSEKGAPG 291

Query: 5403 LPKMKLPQFGISTPGSDLHVNAKG----PQVSGE--LKGPGVDVNLKGPRISAPNVDFNL 5456
             P ++        PG       KG    P + GE  +KG   D+   G R      D   
Sbjct: 292  DPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQ 351

Query: 5457 EG--------PKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPG 5508
            E         P  +G+ G  G   GP    G PG    GL G    PG+K S  +   PG
Sbjct: 352  EKGDEGTPGPPGPRGARGPQGP-SGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG 410

Query: 5509 VNVKLPTGQISGPEIKG--GLKGSEVGFHGAAPDISV-KGP 5546
               K   G    P   G  GL GS  G  G   DI   KGP
Sbjct: 411  ---KDAMGTPGSPGCAGSPGLPGSP-GPPGPPGDIVFRKGP 447



 Score = 35.8 bits (81), Expect = 1.3
 Identities = 123/475 (25%), Positives = 164/475 (34%), Gaps = 73/475 (15%)

Query: 5156 EGDLKG-PKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPS 5214
            E  L+G P    N+G P     G   K  T  F   A +  +P ++  L+G K +     
Sbjct: 1007 EPGLRGIPGSMGNMGMP-----GSKGKRGTLGFPGRAGRPGLPGIH-GLQGDKGEPGYSE 1060

Query: 5215 VGLEGP-----DVDLQGPEAKIKFPKFSMPKIGIPGVKMEGG--GAEVHAQLPSLEGDLR 5267
                GP     D  L G   K    K  M + G PG     G  GA      P L G   
Sbjct: 1061 GTRPGPPGPTGDPGLPGDMGK----KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK-P 1115

Query: 5268 GP--DVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVH 5325
            GP  D+  +G    L  PG+  P      P   GP   + ++G   +  +    P+ +  
Sbjct: 1116 GPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP---MGIRGDQGRDGIPG--PAGEKG 1170

Query: 5326 APGLNLSGVGGKMQVGGDGVK----VPGIDATTKLNVGAPDVTLRGPS----LQGDLAVS 5377
              GL  +  G +   G  G K     PG            D   RGP+      G   + 
Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230

Query: 5378 GDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQ----FGIS-TPGSDLHVNAKGPQVSGE 5432
            G I   +     P      S GS   P    P      GI    GS  H   KGP  +  
Sbjct: 1231 GAIIPGQTGNRGPP----GSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG 1286

Query: 5433 LKGPGVDVNLKG-PRISAPNVDFNLEG-PKVKGSLGATGEI-----KGPTVGGGLPGIGV 5485
              GP   +   G P +  P  D   +G P VKG  G  G +      GP    G PG  V
Sbjct: 1287 DMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG--V 1344

Query: 5486 QGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAPDISVKG 5545
            +G  G L++  +  S      PG     P G    P ++G     E G  G   ++   G
Sbjct: 1345 RGDPGTLKIISLPGS------PG-----PPGTPGEPGMQG-----EPGPPGPPGNL---G 1385

Query: 5546 PAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGP 5600
            P      P  D      GP  + G   S G   P  S  +G   +KG  G+   P
Sbjct: 1386 PCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGS--DGLPGLKGKRGDSGSP 1438



 Score = 35.0 bits (79), Expect = 2.2
 Identities = 58/220 (26%), Positives = 83/220 (37%), Gaps = 41/220 (18%)

Query: 267 LGGRGGVQVPAVDISSSLGGRAVEVQGPSLESGDHGKIKFPTMKVPKFGVSTGREGQTPK 326
           LG  G   +P  D    + G  +   GP    GD G   FP  K      S G  G+  +
Sbjct: 679 LGKCGDPGLPGPDGEPGIPG--IGFPGPPGPKGDQG---FPGTKG-----SLGCPGKMGE 728

Query: 327 AGLRVSAPEVSVGHKGGKPGLTIQAPQLEVSVPSANIEGLEGKLKGPQITGPSLE-GDLG 385
            GL             GKPGL     +  V++P     G  G    P   G S E G++G
Sbjct: 729 PGLP------------GKPGLPGAKGEPAVAMP-----GGPGTPGFPGERGNSGEHGEIG 771

Query: 386 LKGAK----PQGHIGVDASAPQIGGSITGPSVEVQAPDIDVQGPGSKLNVPKMKVPKFSV 441
           L G        G+ G+D   P+      GP  E   P   ++GP     +P        +
Sbjct: 772 LPGLPGLPGTPGNEGLDG--PRGDPGQPGPPGEQGPPGRCIEGPRGAQGLP-------GL 822

Query: 442 SGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLEG 481
           +G KG++     T P G+  +PG+       E  + G+ G
Sbjct: 823 NGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPG 862



 Score = 33.9 bits (76), Expect = 4.9
 Identities = 71/288 (24%), Positives = 100/288 (34%), Gaps = 60/288 (20%)

Query: 2535 PKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPKISMPDFDLHLKG---- 2590
            PK ++ +SG K D        +GP G    P    P      P    P  +  L+G    
Sbjct: 582  PKGELALSGEKGD--------QGPPGDPGSPGSPGPAGPAGPPGYG-PQGEPGLQGTQGV 632

Query: 2591 PKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKMPKVKMPKFSMPG 2650
            P   G    + P+ E  +  P     GP      P  G QGP                PG
Sbjct: 633  PGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHP--GPQGP----------------PG 674

Query: 2651 FKGE-GPDGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKLKGPKFKMPEMNIKAP-KIS 2708
              G  G  GD  LP  D +   P +   GP     GP+G    P  K    ++  P K+ 
Sbjct: 675  IPGSLGKCGDPGLPGPDGEPGIPGIGFPGPP----GPKGDQGFPGTKG---SLGCPGKMG 727

Query: 2709 MPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPK 2768
             P +      P  KG+  V++P   G           P    +  +   HG        +
Sbjct: 728  EPGLPGKPGLPGAKGEPAVAMPGGPGT----------PGFPGERGNSGEHG--------E 769

Query: 2769 IKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGPEG 2816
            I +P   +PG  G   +  ++ P+ D    GP  +   P   IEGP G
Sbjct: 770  IGLP--GLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRG 815


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
            sapiens]
          Length = 1637

 Score = 56.6 bits (135), Expect = 7e-07
 Identities = 141/553 (25%), Positives = 191/553 (34%), Gaps = 92/553 (16%)

Query: 5156 EGDLKGPKVQANLGAPDI-NIEGLDAKVKTPSFGISAPQVSIPDVNVNLKG-PKIKGDVP 5213
            +G+   P +   LG P I    GL  +   P+           D+ ++ KG P + G   
Sbjct: 129  KGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPA--------KEEDIELDAKGDPGLPGAPG 180

Query: 5214 SVGLEGPD-----VDLQGPEAKIKFPKFSMPK-------------IGIPGVK-MEGGGAE 5254
              GL GP      V   GP     FP    P+              G  GVK + G    
Sbjct: 181  PQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGP 240

Query: 5255 VHAQLPSLEGDLRGPDVKLEGPDVSLKG-PGVDLPS--VNLSMPKVSGPDLDLNLKGPSL 5311
                + +L G     D+K E  D    G PG   PS     S     G   D  L+G   
Sbjct: 241  PGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPG 300

Query: 5312 KGDLDASVPSMKVHA----PGL-NLSGVGG-KMQVGGDGVKVPGIDATTKLNVGAPDVTL 5365
            K  +     S  V      PGL    G+ G K  +G  G + P     T    G  + T 
Sbjct: 301  KDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKG-DEGTP 359

Query: 5366 RGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAK 5425
              P  +G     G    P V  G+P  S     G+   P +K  +     PG D      
Sbjct: 360  GPPGPRGARGPQGPSGPPGVP-GSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPG 418

Query: 5426 GPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEI---KGPTVGGGLPG 5482
             P  +G    PG+                    P   G  G  G+I   KGP    GLPG
Sbjct: 419  SPGCAGS---PGL--------------------PGSPGPPGPPGDIVFRKGPPGDHGLPG 455

Query: 5483 I----GVQGLEGNLQMPGIKSSGCDV-----NLPGVNVKLPTGQISGPEIKGGLKGSE-- 5531
                 G+ G++G    PG+  + C        LPG+        I G +   GLKGS   
Sbjct: 456  YLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGS 515

Query: 5532 ---------VGFHGAAPDISVKGPAFNMASPESDFGI----NLKG-PKIKGGADVSGGVS 5577
                      GF GA  D  +KG       PE   G+     L+G P  KG   + G   
Sbjct: 516  PGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG 575

Query: 5578 APDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQA 5637
               +   +G L++ G  G+   P    +          G    GP+ E G++G Q    A
Sbjct: 576  VKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA 635

Query: 5638 PG-LSVSGPQGHL 5649
            PG    +GP+G L
Sbjct: 636  PGPPGEAGPRGEL 648



 Score = 48.9 bits (115), Expect = 1e-04
 Identities = 117/478 (24%), Positives = 164/478 (34%), Gaps = 96/478 (20%)

Query: 5203 LKGPKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSL 5262
            L GP  +  +P +G  GP     GP+    FP  +   +G PG KM   G      LP  
Sbjct: 687  LPGPDGEPGIPGIGFPGPP----GPKGDQGFPG-TKGSLGCPG-KMGEPGLPGKPGLPGA 740

Query: 5263 EGDLRGPDVKLEGPDVSLKGPG----------VDLPSVNLSMPKVSGPDLDLNLKGPSLK 5312
            +G+   P V + G   +   PG          + LP     +P + G   +  L GP  +
Sbjct: 741  KGE---PAVAMPGGPGTPGFPGERGNSGEHGEIGLPG----LPGLPGTPGNEGLDGP--R 791

Query: 5313 GDLDASVPSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQG 5372
            GD     P  +   PG  + G  G   +       PG++             L+G   QG
Sbjct: 792  GDPGQPGPPGEQGPPGRCIEGPRGAQGL-------PGLNG------------LKGQ--QG 830

Query: 5373 DLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGE 5432
                +G    PK   G P L      G               +PG   H    GP   G+
Sbjct: 831  RRGKTG----PKGDPGIPGLDRSGFPGET------------GSPGIPGHQGEMGPL--GQ 872

Query: 5433 LKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNL 5492
               PG +  + GP    P  D  +      G++G  G    P   G     G+ G++G  
Sbjct: 873  RGYPG-NPGILGP----PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQR 927

Query: 5493 QMPGIKSSGCDVNLPGVN-VKLPTGQISGPEIKG-----GLKGSE--VGFHGAAPDISVK 5544
              PG K    D   PG + +    G    P +KG     G KG+    G  G      + 
Sbjct: 928  GTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLP 987

Query: 5545 GPAFNMASPESDFGI--NLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQV 5602
            GPA     P  D G   N   P ++G     G +  P      G L   G  G    P +
Sbjct: 988  GPA-GPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGR---PGL 1043

Query: 5603 SSALNLDTSKFAGGLHFS------GPKVEGGVKG-----GQIGLQAP--GLSVSGPQG 5647
                 L   K   G          GP  + G+ G     G++G   P   L  +GP+G
Sbjct: 1044 PGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEG 1101



 Score = 42.0 bits (97), Expect = 0.018
 Identities = 127/484 (26%), Positives = 169/484 (34%), Gaps = 103/484 (21%)

Query: 5206 PKIKGDVPSVGLEGPDVDLQGP-EAKIKFPKFSMPKIGIPGVKMEGG--GAEVHAQLPSL 5262
            P +KG   + G +G   D   P  ++I      +   G PG+K   G  G + +  +P +
Sbjct: 921  PGVKGQRGTPGAKGEQGDKGNPGPSEISHV---IGDKGEPGLKGFAGNPGEKGNRGVPGM 977

Query: 5263 EG--DLRGPDVKLEGPDVSLKGPGVDLPSV-NLSMPKVSG-PDLDLNLKGPSLKGDLDAS 5318
             G   L+G    L GP     GP  DL S  N   P + G P    N+  P  KG     
Sbjct: 978  PGLKGLKG----LPGP-AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTL 1032

Query: 5319 VPSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSG 5378
                +   PGL   G+ G     G+    PG    T+   G P  T   P L GD+   G
Sbjct: 1033 GFPGRAGRPGL--PGIHGLQGDKGE----PGYSEGTR--PGPPGPT-GDPGLPGDMGKKG 1083

Query: 5379 DIKCPKV--------------SVGAP----------DLSLEASEGSIKLPKMKLPQFGIS 5414
            ++  P                S G+P          DL  +  +G +  P ++ P     
Sbjct: 1084 EMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPG 1143

Query: 5415 TPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGP 5474
             PGS   +  +G Q    + GP  +    G   + P    N      KG  GA G     
Sbjct: 1144 FPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPG----- 1198

Query: 5475 TVGGGLPG-IGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKG-------- 5525
                GLPG  G  G  G     GI+       LPG  +   TG    P  +G        
Sbjct: 1199 --FPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPP 1256

Query: 5526 GLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGE 5585
            G  GS V        I +KG   +M  P         GP  KG    +G +  P      
Sbjct: 1257 GPPGSHV--------IGIKGDKGSMGHP---------GP--KGPPGTAGDMGPP------ 1291

Query: 5586 GHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKG--GQIGLQAPGLSVS 5643
            G L   G+ G   GP+           F G   F G K E G  G  G IG   P +   
Sbjct: 1292 GRLGAPGTPG-LPGPRGDPG-------FQG---FPGVKGEKGNPGFLGSIGPPGP-IGPK 1339

Query: 5644 GPQG 5647
            GP G
Sbjct: 1340 GPPG 1343



 Score = 41.6 bits (96), Expect = 0.024
 Identities = 92/347 (26%), Positives = 129/347 (37%), Gaps = 50/347 (14%)

Query: 5200 NVNLKG-PKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGG--GAEVH 5256
            N  L G P   G     GL+G   +   PE ++  P       G PG++ + G  G +  
Sbjct: 518  NTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVP-------GDPGLRGQPGRKGLDGI 570

Query: 5257 AQLPSLEGDLRGPDVKL--------EGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKG 5308
               P ++G L GP  +L        +GP      PG   P+     P   GP  +  L+G
Sbjct: 571  PGTPGVKG-LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGY-GPQGEPGLQG 628

Query: 5309 PSLKGDLDASVPSMKVHAPGL-NLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRG 5367
                      VP     APG    +G  G++ V      VPG         G P      
Sbjct: 629  TQ-------GVPG----APGPPGEAGPRGELSVS---TPVPGPPGPP----GPPG----H 666

Query: 5368 PSLQGDLAVSGDI-KCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKG 5426
            P  QG   + G + KC    +  PD   E     I  P    P+     PG+   +   G
Sbjct: 667  PGPQGPPGIPGSLGKCGDPGLPGPDG--EPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPG 724

Query: 5427 PQVSGELKG-PGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGI-G 5484
                  L G PG+      P ++ P        P  +G+ G  GEI  P + G LPG  G
Sbjct: 725  KMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPG-LPGTPG 783

Query: 5485 VQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSE 5531
             +GL+G    PG      +   PG  ++ P G    P +  GLKG +
Sbjct: 784  NEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGL-NGLKGQQ 829



 Score = 36.2 bits (82), Expect = 0.99
 Identities = 91/341 (26%), Positives = 116/341 (34%), Gaps = 48/341 (14%)

Query: 5241 IGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLS------M 5294
            +G+PG      G++     P L G L  P +         KG       + L       +
Sbjct: 120  VGVPGCS----GSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGL 175

Query: 5295 PKVSGPDLDLNLKGP-SLKGDLDASVPSMKVHAPG-LNLSGVGGKM------QVGGDGVK 5346
            P   GP     L GP    G +    P      PG +   G  G M        G  GVK
Sbjct: 176  PGAPGPQ---GLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVK 232

Query: 5347 ----VPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIK 5402
                 PG   T  + +  PD        +GD    G+   P  S G P  S  + +G+  
Sbjct: 233  GLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPS-GLPGESYGSEKGAPG 291

Query: 5403 LPKMKLPQFGISTPGSDLHVNAKG----PQVSGE--LKGPGVDVNLKGPRISAPNVDFNL 5456
             P ++        PG       KG    P + GE  +KG   D+   G R      D   
Sbjct: 292  DPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQ 351

Query: 5457 EG--------PKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPG 5508
            E         P  +G+ G  G   GP    G PG    GL G    PG+K S  +   PG
Sbjct: 352  EKGDEGTPGPPGPRGARGPQGP-SGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG 410

Query: 5509 VNVKLPTGQISGPEIKG--GLKGSEVGFHGAAPDISV-KGP 5546
               K   G    P   G  GL GS  G  G   DI   KGP
Sbjct: 411  ---KDAMGTPGSPGCAGSPGLPGSP-GPPGPPGDIVFRKGP 447



 Score = 35.8 bits (81), Expect = 1.3
 Identities = 123/475 (25%), Positives = 164/475 (34%), Gaps = 73/475 (15%)

Query: 5156 EGDLKG-PKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPS 5214
            E  L+G P    N+G P     G   K  T  F   A +  +P ++  L+G K +     
Sbjct: 1007 EPGLRGIPGSMGNMGMP-----GSKGKRGTLGFPGRAGRPGLPGIH-GLQGDKGEPGYSE 1060

Query: 5215 VGLEGP-----DVDLQGPEAKIKFPKFSMPKIGIPGVKMEGG--GAEVHAQLPSLEGDLR 5267
                GP     D  L G   K    K  M + G PG     G  GA      P L G   
Sbjct: 1061 GTRPGPPGPTGDPGLPGDMGK----KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK-P 1115

Query: 5268 GP--DVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVH 5325
            GP  D+  +G    L  PG+  P      P   GP   + ++G   +  +    P+ +  
Sbjct: 1116 GPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP---MGIRGDQGRDGIPG--PAGEKG 1170

Query: 5326 APGLNLSGVGGKMQVGGDGVK----VPGIDATTKLNVGAPDVTLRGPS----LQGDLAVS 5377
              GL  +  G +   G  G K     PG            D   RGP+      G   + 
Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230

Query: 5378 GDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQ----FGIS-TPGSDLHVNAKGPQVSGE 5432
            G I   +     P      S GS   P    P      GI    GS  H   KGP  +  
Sbjct: 1231 GAIIPGQTGNRGPP----GSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG 1286

Query: 5433 LKGPGVDVNLKG-PRISAPNVDFNLEG-PKVKGSLGATGEI-----KGPTVGGGLPGIGV 5485
              GP   +   G P +  P  D   +G P VKG  G  G +      GP    G PG  V
Sbjct: 1287 DMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG--V 1344

Query: 5486 QGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAPDISVKG 5545
            +G  G L++  +  S      PG     P G    P ++G     E G  G   ++   G
Sbjct: 1345 RGDPGTLKIISLPGS------PG-----PPGTPGEPGMQG-----EPGPPGPPGNL---G 1385

Query: 5546 PAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGP 5600
            P      P  D      GP  + G   S G   P  S  +G   +KG  G+   P
Sbjct: 1386 PCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGS--DGLPGLKGKRGDSGSP 1438



 Score = 35.0 bits (79), Expect = 2.2
 Identities = 58/220 (26%), Positives = 83/220 (37%), Gaps = 41/220 (18%)

Query: 267 LGGRGGVQVPAVDISSSLGGRAVEVQGPSLESGDHGKIKFPTMKVPKFGVSTGREGQTPK 326
           LG  G   +P  D    + G  +   GP    GD G   FP  K      S G  G+  +
Sbjct: 679 LGKCGDPGLPGPDGEPGIPG--IGFPGPPGPKGDQG---FPGTKG-----SLGCPGKMGE 728

Query: 327 AGLRVSAPEVSVGHKGGKPGLTIQAPQLEVSVPSANIEGLEGKLKGPQITGPSLE-GDLG 385
            GL             GKPGL     +  V++P     G  G    P   G S E G++G
Sbjct: 729 PGLP------------GKPGLPGAKGEPAVAMP-----GGPGTPGFPGERGNSGEHGEIG 771

Query: 386 LKGAK----PQGHIGVDASAPQIGGSITGPSVEVQAPDIDVQGPGSKLNVPKMKVPKFSV 441
           L G        G+ G+D   P+      GP  E   P   ++GP     +P        +
Sbjct: 772 LPGLPGLPGTPGNEGLDG--PRGDPGQPGPPGEQGPPGRCIEGPRGAQGLP-------GL 822

Query: 442 SGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLEG 481
           +G KG++     T P G+  +PG+       E  + G+ G
Sbjct: 823 NGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPG 862



 Score = 33.9 bits (76), Expect = 4.9
 Identities = 71/288 (24%), Positives = 100/288 (34%), Gaps = 60/288 (20%)

Query: 2535 PKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPKISMPDFDLHLKG---- 2590
            PK ++ +SG K D        +GP G    P    P      P    P  +  L+G    
Sbjct: 582  PKGELALSGEKGD--------QGPPGDPGSPGSPGPAGPAGPPGYG-PQGEPGLQGTQGV 632

Query: 2591 PKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKMPKVKMPKFSMPG 2650
            P   G    + P+ E  +  P     GP      P  G QGP                PG
Sbjct: 633  PGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHP--GPQGP----------------PG 674

Query: 2651 FKGE-GPDGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKLKGPKFKMPEMNIKAP-KIS 2708
              G  G  GD  LP  D +   P +   GP     GP+G    P  K    ++  P K+ 
Sbjct: 675  IPGSLGKCGDPGLPGPDGEPGIPGIGFPGPP----GPKGDQGFPGTKG---SLGCPGKMG 727

Query: 2709 MPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPK 2768
             P +      P  KG+  V++P   G           P    +  +   HG        +
Sbjct: 728  EPGLPGKPGLPGAKGEPAVAMPGGPGT----------PGFPGERGNSGEHG--------E 769

Query: 2769 IKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGPEG 2816
            I +P   +PG  G   +  ++ P+ D    GP  +   P   IEGP G
Sbjct: 770  IGLP--GLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRG 815


>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
            sapiens]
          Length = 1670

 Score = 56.6 bits (135), Expect = 7e-07
 Identities = 141/553 (25%), Positives = 191/553 (34%), Gaps = 92/553 (16%)

Query: 5156 EGDLKGPKVQANLGAPDI-NIEGLDAKVKTPSFGISAPQVSIPDVNVNLKG-PKIKGDVP 5213
            +G+   P +   LG P I    GL  +   P+           D+ ++ KG P + G   
Sbjct: 129  KGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPA--------KEEDIELDAKGDPGLPGAPG 180

Query: 5214 SVGLEGPD-----VDLQGPEAKIKFPKFSMPK-------------IGIPGVK-MEGGGAE 5254
              GL GP      V   GP     FP    P+              G  GVK + G    
Sbjct: 181  PQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGP 240

Query: 5255 VHAQLPSLEGDLRGPDVKLEGPDVSLKG-PGVDLPS--VNLSMPKVSGPDLDLNLKGPSL 5311
                + +L G     D+K E  D    G PG   PS     S     G   D  L+G   
Sbjct: 241  PGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPG 300

Query: 5312 KGDLDASVPSMKVHA----PGL-NLSGVGG-KMQVGGDGVKVPGIDATTKLNVGAPDVTL 5365
            K  +     S  V      PGL    G+ G K  +G  G + P     T    G  + T 
Sbjct: 301  KDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKG-DEGTP 359

Query: 5366 RGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAK 5425
              P  +G     G    P V  G+P  S     G+   P +K  +     PG D      
Sbjct: 360  GPPGPRGARGPQGPSGPPGVP-GSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPG 418

Query: 5426 GPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEI---KGPTVGGGLPG 5482
             P  +G    PG+                    P   G  G  G+I   KGP    GLPG
Sbjct: 419  SPGCAGS---PGL--------------------PGSPGPPGPPGDIVFRKGPPGDHGLPG 455

Query: 5483 I----GVQGLEGNLQMPGIKSSGCDV-----NLPGVNVKLPTGQISGPEIKGGLKGSE-- 5531
                 G+ G++G    PG+  + C        LPG+        I G +   GLKGS   
Sbjct: 456  YLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGS 515

Query: 5532 ---------VGFHGAAPDISVKGPAFNMASPESDFGI----NLKG-PKIKGGADVSGGVS 5577
                      GF GA  D  +KG       PE   G+     L+G P  KG   + G   
Sbjct: 516  PGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG 575

Query: 5578 APDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQA 5637
               +   +G L++ G  G+   P    +          G    GP+ E G++G Q    A
Sbjct: 576  VKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA 635

Query: 5638 PG-LSVSGPQGHL 5649
            PG    +GP+G L
Sbjct: 636  PGPPGEAGPRGEL 648



 Score = 48.9 bits (115), Expect = 1e-04
 Identities = 117/478 (24%), Positives = 164/478 (34%), Gaps = 96/478 (20%)

Query: 5203 LKGPKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSL 5262
            L GP  +  +P +G  GP     GP+    FP  +   +G PG KM   G      LP  
Sbjct: 687  LPGPDGEPGIPGIGFPGPP----GPKGDQGFPG-TKGSLGCPG-KMGEPGLPGKPGLPGA 740

Query: 5263 EGDLRGPDVKLEGPDVSLKGPG----------VDLPSVNLSMPKVSGPDLDLNLKGPSLK 5312
            +G+   P V + G   +   PG          + LP     +P + G   +  L GP  +
Sbjct: 741  KGE---PAVAMPGGPGTPGFPGERGNSGEHGEIGLPG----LPGLPGTPGNEGLDGP--R 791

Query: 5313 GDLDASVPSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQG 5372
            GD     P  +   PG  + G  G   +       PG++             L+G   QG
Sbjct: 792  GDPGQPGPPGEQGPPGRCIEGPRGAQGL-------PGLNG------------LKGQ--QG 830

Query: 5373 DLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGE 5432
                +G    PK   G P L      G               +PG   H    GP   G+
Sbjct: 831  RRGKTG----PKGDPGIPGLDRSGFPGET------------GSPGIPGHQGEMGPL--GQ 872

Query: 5433 LKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNL 5492
               PG +  + GP    P  D  +      G++G  G    P   G     G+ G++G  
Sbjct: 873  RGYPG-NPGILGP----PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQR 927

Query: 5493 QMPGIKSSGCDVNLPGVN-VKLPTGQISGPEIKG-----GLKGSE--VGFHGAAPDISVK 5544
              PG K    D   PG + +    G    P +KG     G KG+    G  G      + 
Sbjct: 928  GTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLP 987

Query: 5545 GPAFNMASPESDFGI--NLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQV 5602
            GPA     P  D G   N   P ++G     G +  P      G L   G  G    P +
Sbjct: 988  GPA-GPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGR---PGL 1043

Query: 5603 SSALNLDTSKFAGGLHFS------GPKVEGGVKG-----GQIGLQAP--GLSVSGPQG 5647
                 L   K   G          GP  + G+ G     G++G   P   L  +GP+G
Sbjct: 1044 PGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEG 1101



 Score = 42.0 bits (97), Expect = 0.018
 Identities = 127/484 (26%), Positives = 169/484 (34%), Gaps = 103/484 (21%)

Query: 5206 PKIKGDVPSVGLEGPDVDLQGP-EAKIKFPKFSMPKIGIPGVKMEGG--GAEVHAQLPSL 5262
            P +KG   + G +G   D   P  ++I      +   G PG+K   G  G + +  +P +
Sbjct: 921  PGVKGQRGTPGAKGEQGDKGNPGPSEISHV---IGDKGEPGLKGFAGNPGEKGNRGVPGM 977

Query: 5263 EG--DLRGPDVKLEGPDVSLKGPGVDLPSV-NLSMPKVSG-PDLDLNLKGPSLKGDLDAS 5318
             G   L+G    L GP     GP  DL S  N   P + G P    N+  P  KG     
Sbjct: 978  PGLKGLKG----LPGP-AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTL 1032

Query: 5319 VPSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSG 5378
                +   PGL   G+ G     G+    PG    T+   G P  T   P L GD+   G
Sbjct: 1033 GFPGRAGRPGL--PGIHGLQGDKGE----PGYSEGTR--PGPPGPT-GDPGLPGDMGKKG 1083

Query: 5379 DIKCPKV--------------SVGAP----------DLSLEASEGSIKLPKMKLPQFGIS 5414
            ++  P                S G+P          DL  +  +G +  P ++ P     
Sbjct: 1084 EMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPG 1143

Query: 5415 TPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGP 5474
             PGS   +  +G Q    + GP  +    G   + P    N      KG  GA G     
Sbjct: 1144 FPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPG----- 1198

Query: 5475 TVGGGLPG-IGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKG-------- 5525
                GLPG  G  G  G     GI+       LPG  +   TG    P  +G        
Sbjct: 1199 --FPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPP 1256

Query: 5526 GLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGE 5585
            G  GS V        I +KG   +M  P         GP  KG    +G +  P      
Sbjct: 1257 GPPGSHV--------IGIKGDKGSMGHP---------GP--KGPPGTAGDMGPP------ 1291

Query: 5586 GHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKG--GQIGLQAPGLSVS 5643
            G L   G+ G   GP+           F G   F G K E G  G  G IG   P +   
Sbjct: 1292 GRLGAPGTPG-LPGPRGDPG-------FQG---FPGVKGEKGNPGFLGSIGPPGP-IGPK 1339

Query: 5644 GPQG 5647
            GP G
Sbjct: 1340 GPPG 1343



 Score = 41.6 bits (96), Expect = 0.024
 Identities = 92/347 (26%), Positives = 129/347 (37%), Gaps = 50/347 (14%)

Query: 5200 NVNLKG-PKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGG--GAEVH 5256
            N  L G P   G     GL+G   +   PE ++  P       G PG++ + G  G +  
Sbjct: 518  NTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVP-------GDPGLRGQPGRKGLDGI 570

Query: 5257 AQLPSLEGDLRGPDVKL--------EGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKG 5308
               P ++G L GP  +L        +GP      PG   P+     P   GP  +  L+G
Sbjct: 571  PGTPGVKG-LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGY-GPQGEPGLQG 628

Query: 5309 PSLKGDLDASVPSMKVHAPGL-NLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRG 5367
                      VP     APG    +G  G++ V      VPG         G P      
Sbjct: 629  TQ-------GVPG----APGPPGEAGPRGELSVS---TPVPGPPGPP----GPPG----H 666

Query: 5368 PSLQGDLAVSGDI-KCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKG 5426
            P  QG   + G + KC    +  PD   E     I  P    P+     PG+   +   G
Sbjct: 667  PGPQGPPGIPGSLGKCGDPGLPGPDG--EPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPG 724

Query: 5427 PQVSGELKG-PGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGI-G 5484
                  L G PG+      P ++ P        P  +G+ G  GEI  P + G LPG  G
Sbjct: 725  KMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPG-LPGTPG 783

Query: 5485 VQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSE 5531
             +GL+G    PG      +   PG  ++ P G    P +  GLKG +
Sbjct: 784  NEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGL-NGLKGQQ 829



 Score = 36.2 bits (82), Expect = 0.99
 Identities = 91/341 (26%), Positives = 116/341 (34%), Gaps = 48/341 (14%)

Query: 5241 IGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLS------M 5294
            +G+PG      G++     P L G L  P +         KG       + L       +
Sbjct: 120  VGVPGCS----GSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGL 175

Query: 5295 PKVSGPDLDLNLKGP-SLKGDLDASVPSMKVHAPG-LNLSGVGGKM------QVGGDGVK 5346
            P   GP     L GP    G +    P      PG +   G  G M        G  GVK
Sbjct: 176  PGAPGPQ---GLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVK 232

Query: 5347 ----VPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIK 5402
                 PG   T  + +  PD        +GD    G+   P  S G P  S  + +G+  
Sbjct: 233  GLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPS-GLPGESYGSEKGAPG 291

Query: 5403 LPKMKLPQFGISTPGSDLHVNAKG----PQVSGE--LKGPGVDVNLKGPRISAPNVDFNL 5456
             P ++        PG       KG    P + GE  +KG   D+   G R      D   
Sbjct: 292  DPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQ 351

Query: 5457 EG--------PKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPG 5508
            E         P  +G+ G  G   GP    G PG    GL G    PG+K S  +   PG
Sbjct: 352  EKGDEGTPGPPGPRGARGPQGP-SGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG 410

Query: 5509 VNVKLPTGQISGPEIKG--GLKGSEVGFHGAAPDISV-KGP 5546
               K   G    P   G  GL GS  G  G   DI   KGP
Sbjct: 411  ---KDAMGTPGSPGCAGSPGLPGSP-GPPGPPGDIVFRKGP 447



 Score = 35.8 bits (81), Expect = 1.3
 Identities = 123/475 (25%), Positives = 164/475 (34%), Gaps = 73/475 (15%)

Query: 5156 EGDLKG-PKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPS 5214
            E  L+G P    N+G P     G   K  T  F   A +  +P ++  L+G K +     
Sbjct: 1007 EPGLRGIPGSMGNMGMP-----GSKGKRGTLGFPGRAGRPGLPGIH-GLQGDKGEPGYSE 1060

Query: 5215 VGLEGP-----DVDLQGPEAKIKFPKFSMPKIGIPGVKMEGG--GAEVHAQLPSLEGDLR 5267
                GP     D  L G   K    K  M + G PG     G  GA      P L G   
Sbjct: 1061 GTRPGPPGPTGDPGLPGDMGK----KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK-P 1115

Query: 5268 GP--DVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVH 5325
            GP  D+  +G    L  PG+  P      P   GP   + ++G   +  +    P+ +  
Sbjct: 1116 GPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP---MGIRGDQGRDGIPG--PAGEKG 1170

Query: 5326 APGLNLSGVGGKMQVGGDGVK----VPGIDATTKLNVGAPDVTLRGPS----LQGDLAVS 5377
              GL  +  G +   G  G K     PG            D   RGP+      G   + 
Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230

Query: 5378 GDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQ----FGIS-TPGSDLHVNAKGPQVSGE 5432
            G I   +     P      S GS   P    P      GI    GS  H   KGP  +  
Sbjct: 1231 GAIIPGQTGNRGPP----GSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG 1286

Query: 5433 LKGPGVDVNLKG-PRISAPNVDFNLEG-PKVKGSLGATGEI-----KGPTVGGGLPGIGV 5485
              GP   +   G P +  P  D   +G P VKG  G  G +      GP    G PG  V
Sbjct: 1287 DMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG--V 1344

Query: 5486 QGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAPDISVKG 5545
            +G  G L++  +  S      PG     P G    P ++G     E G  G   ++   G
Sbjct: 1345 RGDPGTLKIISLPGS------PG-----PPGTPGEPGMQG-----EPGPPGPPGNL---G 1385

Query: 5546 PAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGP 5600
            P      P  D      GP  + G   S G   P  S  +G   +KG  G+   P
Sbjct: 1386 PCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGS--DGLPGLKGKRGDSGSP 1438



 Score = 35.0 bits (79), Expect = 2.2
 Identities = 58/220 (26%), Positives = 83/220 (37%), Gaps = 41/220 (18%)

Query: 267 LGGRGGVQVPAVDISSSLGGRAVEVQGPSLESGDHGKIKFPTMKVPKFGVSTGREGQTPK 326
           LG  G   +P  D    + G  +   GP    GD G   FP  K      S G  G+  +
Sbjct: 679 LGKCGDPGLPGPDGEPGIPG--IGFPGPPGPKGDQG---FPGTKG-----SLGCPGKMGE 728

Query: 327 AGLRVSAPEVSVGHKGGKPGLTIQAPQLEVSVPSANIEGLEGKLKGPQITGPSLE-GDLG 385
            GL             GKPGL     +  V++P     G  G    P   G S E G++G
Sbjct: 729 PGLP------------GKPGLPGAKGEPAVAMP-----GGPGTPGFPGERGNSGEHGEIG 771

Query: 386 LKGAK----PQGHIGVDASAPQIGGSITGPSVEVQAPDIDVQGPGSKLNVPKMKVPKFSV 441
           L G        G+ G+D   P+      GP  E   P   ++GP     +P        +
Sbjct: 772 LPGLPGLPGTPGNEGLDG--PRGDPGQPGPPGEQGPPGRCIEGPRGAQGLP-------GL 822

Query: 442 SGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLEG 481
           +G KG++     T P G+  +PG+       E  + G+ G
Sbjct: 823 NGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPG 862



 Score = 33.9 bits (76), Expect = 4.9
 Identities = 71/288 (24%), Positives = 100/288 (34%), Gaps = 60/288 (20%)

Query: 2535 PKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPKISMPDFDLHLKG---- 2590
            PK ++ +SG K D        +GP G    P    P      P    P  +  L+G    
Sbjct: 582  PKGELALSGEKGD--------QGPPGDPGSPGSPGPAGPAGPPGYG-PQGEPGLQGTQGV 632

Query: 2591 PKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKMPKVKMPKFSMPG 2650
            P   G    + P+ E  +  P     GP      P  G QGP                PG
Sbjct: 633  PGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHP--GPQGP----------------PG 674

Query: 2651 FKGE-GPDGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKLKGPKFKMPEMNIKAP-KIS 2708
              G  G  GD  LP  D +   P +   GP     GP+G    P  K    ++  P K+ 
Sbjct: 675  IPGSLGKCGDPGLPGPDGEPGIPGIGFPGPP----GPKGDQGFPGTKG---SLGCPGKMG 727

Query: 2709 MPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPK 2768
             P +      P  KG+  V++P   G           P    +  +   HG        +
Sbjct: 728  EPGLPGKPGLPGAKGEPAVAMPGGPGT----------PGFPGERGNSGEHG--------E 769

Query: 2769 IKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGPEG 2816
            I +P   +PG  G   +  ++ P+ D    GP  +   P   IEGP G
Sbjct: 770  IGLP--GLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRG 815


>gi|126352322 elastin isoform c precursor [Homo sapiens]
          Length = 692

 Score = 56.2 bits (134), Expect = 9e-07
 Identities = 124/472 (26%), Positives = 164/472 (34%), Gaps = 64/472 (13%)

Query: 5210 GDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEG---GGAEVHAQLPS---LE 5263
            G VP VG  G       P A +  P   +    +PGV + G   GG    A+ P    L 
Sbjct: 113  GGVPGVGGLGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLP 172

Query: 5264 GDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMK 5323
            G   G  VK + P V   G    +P V        G  L   +K P L G       + K
Sbjct: 173  GVPTGAGVKPKAPGVG--GAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK 230

Query: 5324 V---HAPGLNLSGVGGKMQ------VGGDGVKVPGIDATTKLNVGA----PDVTLRG-PS 5369
            +   + PG  ++G  GK        VG          A  K   GA    P V   G P 
Sbjct: 231  LPYGYGPG-GVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPG 289

Query: 5370 LQGDLAVSGDIK---CPKVSVGAPDLSLEASEGSIKLPKMKLPQFG---ISTPGSDLHVN 5423
            + G +   G I     P  +  A   +  A  G+        P FG   +  PG+   V 
Sbjct: 290  VPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAG--VP 347

Query: 5424 AKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGG----- 5478
              G   +G    PG  +    P  + P V       K        G   G  VGG     
Sbjct: 348  GVGVPGAGIPVVPGAGI----PGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYG 403

Query: 5479 ----GLPG--IGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEV 5532
                G PG  +GV G+ G   +PG+        +PGV +  P  Q +    K    G   
Sbjct: 404  VGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGIS-PEAQ-AAAAAKAAKYGLVP 461

Query: 5533 GFHGAAPDISVKGPAFNMASPESDFGINL-KGPKIKGGADVSGGVS-APDISLGEGHLSV 5590
            G  G AP + V  P   +A      G+ L  G  +  G  V+ GV  AP I  G    + 
Sbjct: 462  GV-GVAPGVGV-APGVGVAP-----GVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAA 514

Query: 5591 KGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQAPGLSV 5642
            K +       Q+ +A  L       G    G  V  GV G  +G   PGL V
Sbjct: 515  KSAAKVAAKAQLRAAAGL-------GAGIPGLGVGVGVPGLGVGAGVPGLGV 559



 Score = 38.1 bits (87), Expect = 0.26
 Identities = 88/316 (27%), Positives = 126/316 (39%), Gaps = 55/316 (17%)

Query: 5185 PSFG---ISAPQVSIPDVNVNLKGPKIKGDVPSVGLEGPDVD-LQGPEAKIKFP----KF 5236
            P FG   +  P   +P V V   G  +   VP  G+ G  V  +  PEA  K      K+
Sbjct: 332  PGFGPGVVGVPGAGVPGVGVPGAGIPV---VPGAGIPGAAVPGVVSPEAAAKAAAKAAKY 388

Query: 5237 -SMPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVD-LPSVNLSM 5294
             + P +G+ G+   G GA          G   G  V + G       PGV  +P V   +
Sbjct: 389  GARPGVGVGGIPTYGVGA----------GGFPGFGVGVGGIPGVAGVPGVGGVPGVG-GV 437

Query: 5295 PKVS-GPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLS-GVGGKMQVG---GDGVKVPG 5349
            P V   P+        + K  L   VP + V APG+ ++ GVG    VG   G GV  PG
Sbjct: 438  PGVGISPEAQAAAAAKAAKYGL---VPGVGV-APGVGVAPGVGVAPGVGLAPGVGV-APG 492

Query: 5350 IDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEG-SIKLPKMKL 5408
            +     + V AP +   GP   G +A +      KV+  A    L A+ G    +P + +
Sbjct: 493  VGVAPGVGV-APGI---GP---GGVAAAAK-SAAKVAAKA---QLRAAAGLGAGIPGLGV 541

Query: 5409 PQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGAT 5468
               G+  PG  +     G  V   + G G    + G   +A    +   G  V G LG  
Sbjct: 542  ---GVGVPGLGVGAGVPGLGVGAGVPGFGA---VPGALAAAKAAKY---GAAVPGVLGGL 592

Query: 5469 GEIKGPTVGGGLPGIG 5484
            G + G  + GG+ G G
Sbjct: 593  GALGGVGIPGGVVGAG 608



 Score = 38.1 bits (87), Expect = 0.26
 Identities = 84/358 (23%), Positives = 125/358 (34%), Gaps = 68/358 (18%)

Query: 5238 MPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKV 5297
            +P  G+PGV + G G  V             P   + G  V    PGV  P         
Sbjct: 341  VPGAGVPGVGVPGAGIPVV------------PGAGIPGAAV----PGVVSPEAAAKAAAK 384

Query: 5298 S---GPDLDLNLKGPSLKGDLDASVPSMKVHAPGL----NLSGVGGKMQVGGDGVKVPGI 5350
            +   G    + + G    G      P   V   G+     + GVGG   VGG    VPG+
Sbjct: 385  AAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGG----VPGV 440

Query: 5351 DATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQ 5410
              + +    A     +   + G     G    P V V AP + L    G         P 
Sbjct: 441  GISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGV-APGVGLAPGVGVA-------PG 492

Query: 5411 FGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGE 5470
             G++ PG  +      P +     GPG      G   +A +        +++ + G    
Sbjct: 493  VGVA-PGVGV-----APGI-----GPG------GVAAAAKSAAKVAAKAQLRAAAGLGAG 535

Query: 5471 IKGPTVGGGLPGIGV----------QGLEGNLQMPG----IKSSGCDVNLPGVNVKLPTG 5516
            I G  VG G+PG+GV           G+ G   +PG     K++     +PGV   L  G
Sbjct: 536  IPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGL--G 593

Query: 5517 QISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSG 5574
             + G  I GG+ G+      AA   + K   F +       G+ + G  + G   + G
Sbjct: 594  ALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGG 651


>gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens]
          Length = 1142

 Score = 56.2 bits (134), Expect = 9e-07
 Identities = 145/543 (26%), Positives = 189/543 (34%), Gaps = 85/543 (15%)

Query: 5206 PKIKGDVPSVGLEGPDVDLQGPEAKIKFP-KFSMP-KIGIPGVKMEGGGAEVHAQLPSLE 5263
            P +KG   S G  GP    +GP   +  P +  +P K GI G K + GG      LP  +
Sbjct: 521  PGLKGQQGSAGSMGP----RGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPK 576

Query: 5264 GDLRGPDVKLEGP---DVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVP 5320
            G+   P   L G    D +   PG   P     +P V G   D+  +G  + G   A  P
Sbjct: 577  GEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGP 636

Query: 5321 SMKVHAPG-LNLSGVGGKMQV-GGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSG 5378
            + +    G   L G+ G     G DGV  PG D    L  G P   +  P L GD+    
Sbjct: 637  AGEPGIQGPRGLPGLPGTPGTPGNDGV--PGRDGKPGLP-GPPGDPIALPLL-GDIGALL 692

Query: 5379 DIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGV 5438
               C       P L     E           + G   PG    +  KG            
Sbjct: 693  KNFCGNCQASVPGLKSNKGE-----------EGGAGEPGKYDSMARKG------------ 729

Query: 5439 DVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPGIK 5498
            D+  +GP    P +    EGPK     G+ GE   P + G     G+QG+ G    PG  
Sbjct: 730  DIGPRGP----PGIP-GREGPK-----GSKGERGYPGIPGEKGDEGLQGIPGIPGAPG-- 777

Query: 5499 SSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFG 5558
                    PG+  +  TG   GP    G KGS+ G  G        G  FN  +  S   
Sbjct: 778  ----PTGPPGLMGR--TGH-PGPTGAKGEKGSD-GPPGKPGPPGPPGIPFNERNGMSSL- 828

Query: 5559 INLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLH 5618
                  KIKGG +V      P      G    KG  G    P       L+   F G   
Sbjct: 829  -----YKIKGGVNVPSYPGPP------GPPGPKGDPGPVGEPGAMGLPGLE--GFPGVKG 875

Query: 5619 FSGPKVEGGVKGGQIGLQAPG-LSVSGPQGHLESGSGKVTFPKMKIP--KFTFSGRELVG 5675
              GP    G+ G      APG   V G  G      G + FP  + P  K   +G++ + 
Sbjct: 876  DRGPAGPPGIAGMSGKPGAPGPPGVPGEPGE-RGPVGDIGFPGPEGPSGKPGINGKDGIP 934

Query: 5676 REMGV----DVHFPKAEASIQAGAGD--GEWEESEVKLKKSKIKMPKFNFSKPKGKGGVT 5729
               G+        PK E   Q   GD   + E  +  L   K  +       P G  G  
Sbjct: 935  GAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMG---PPGNKGSM 991

Query: 5730 GSP 5732
            GSP
Sbjct: 992  GSP 994


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score = 55.8 bits (133), Expect = 1e-06
 Identities = 137/510 (26%), Positives = 180/510 (35%), Gaps = 125/510 (24%)

Query: 5204 KGPKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPK--IGIPGVKMEGG-----GAEVH 5256
            KG + +G   + G +G  V   GP     FP    P    G+PG+    G     G  + 
Sbjct: 386  KGQQFEGPPGAPGPQGV-VGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIM 444

Query: 5257 AQLPSLEGDLRGPDVK---------LEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLK 5307
                   G  +GP V          L+   +S+KGP   +         ++G    + L 
Sbjct: 445  MPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVG--------LTGRPGPVGLP 496

Query: 5308 G-PSLKGDLDASVPS-----MKVHAPGLNLSGVGGKM-QVGGDGVK-VPGIDATTKLNVG 5359
            G P LKG+  A  P         H P     G  GKM + G DG + +PG D   K + G
Sbjct: 497  GHPGLKGEEGAEGPQGPRGLQGPHGP----PGRVGKMGRPGADGARGLPG-DTGPKGDRG 551

Query: 5360 APDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSD 5419
               +    P L G+    GD       VG P                         PG D
Sbjct: 552  FDGL----PGLPGEKGQRGDFG----HVGQP-----------------------GPPGED 580

Query: 5420 LHVNAKGPQ-VSGELKGPGVDVNLKGPRISA-----PNVDFNLEGPKVKGSLGATGEIKG 5473
                A+GP   +G+   PG    L GPR S      P V      P  KG++G  GE   
Sbjct: 581  GERGAEGPPGPTGQAGEPGPR-GLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGP 639

Query: 5474 PTVGG-----GLPG-------IGVQGLEGNLQMPGIKSSGCDVNLPG-------VNVKLP 5514
            P   G     GLPG        G +G  GN  +PG+  S   +  PG          + P
Sbjct: 640  PGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGP 699

Query: 5515 TGQISGPEIKG--GLKGS--------------EVGFHGAAPDISVKGPAFNMASPESDFG 5558
             G    P   G  G+KG+              E GF G   D+ +KG      +P     
Sbjct: 700  PGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGE 759

Query: 5559 INLKGPKIKGGADVSGGVSAPDISLGE-GHLSVKGSGGEWKGPQVSSALNLDTSKFAGGL 5617
               +GPK + G     G   P  S GE G L V G  G    P    ++      F G L
Sbjct: 760  DGPEGPKGQAG---QAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIG-----FPGPL 811

Query: 5618 HFSGPKVEGGVKGGQIGLQAPGLSVSGPQG 5647
               G K + G K GQ GL+       GP G
Sbjct: 812  GPIGEKGKSG-KTGQPGLEGE----RGPPG 836



 Score = 42.0 bits (97), Expect = 0.018
 Identities = 101/369 (27%), Positives = 123/369 (33%), Gaps = 53/369 (14%)

Query: 211  GSGAASPTGSAVDIRA-GAISASG-PELQGAGHSKLQVTMPGIKVGGSGVNVNAKGLDLG 268
            G G   PTG   D    G + A+G P  +G       + +PG       V    K    G
Sbjct: 984  GPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRG 1043

Query: 269  GRGGVQVPAVD-ISSSLGGRAVE-VQGPSLESGDHGKIKFPTMKVPKFGVSTGREGQTPK 326
             RG       D I   LG        GPS E GD G +  P  K  K     G  G   +
Sbjct: 1044 ERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKG--DKGDAGPPGQ 1101

Query: 327  AGLRVSA----PEVSVGHKG--GKPGLTIQAPQLEVSVPSANIEGLEGKLKGPQITGPSL 380
             G+R  A    P  + G +G  G PGL  Q            + G  G + GP    P L
Sbjct: 1102 PGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGD-------DGVRGFVGVI-GP----PGL 1149

Query: 381  EGDLGLKGAKPQGHIG-VDASAPQIGGSITGPSVEVQAPDIDVQGPGSKLNVPKMK--VP 437
            +G  G  G K  G +G V +  P       GP           QGP      P +   V 
Sbjct: 1150 QGLPGPPGEK--GEVGDVGSMGPHGAPGPRGP-----------QGPTGSEGTPGLPGGVG 1196

Query: 438  KFSVSGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLEGKMKGTKVKTPEMIIQK 497
            +    G KGE        P G   +PG  GD+   E    G  G       K P      
Sbjct: 1197 QPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIG--EKGDSGPSGAAGPPGKKGPP----- 1249

Query: 498  PKISMQDVDLSLGSPKLKGDI-KVSAPGVQGDVKGPQVALKGSRVDIETPNLEGTLTGPR 556
                      S+G   L GD+     PGV G    P    KG   D+  P   G    P 
Sbjct: 1250 ---GEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSP--GEKGDPGDVGGPGPPGASGEPG 1304

Query: 557  LGSPSGKTG 565
               P GK G
Sbjct: 1305 APGPPGKRG 1313



 Score = 41.6 bits (96), Expect = 0.024
 Identities = 78/272 (28%), Positives = 97/272 (35%), Gaps = 44/272 (16%)

Query: 5397 SEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNL 5456
            SEG+  LP       G+  PG+   V  KG +  G+   PG       P I  P  D   
Sbjct: 1185 SEGTPGLPG------GVGQPGA---VGEKGER--GDAGDPGPP---GAPGIPGPKGDIGE 1230

Query: 5457 EGPK-VKGSLGATGEIKGPTVGGGLPGIGVQGLEGNL------------QMPGIKSSGCD 5503
            +G     G+ G  G+   P   G    +G  GL G+L              PG K    D
Sbjct: 1231 KGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGD 1290

Query: 5504 VNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKG 5563
            V  PG           GP  K G  G  +G  G   +   KG       P     +  +G
Sbjct: 1291 VGGPGPPGASGEPGAPGPPGKRGPSG-HMGREGREGEKGAKGEPGPDGPPGRTGPMGARG 1349

Query: 5564 PKIKGGADVSGGVSAPDISLGE-GHLSVKGSGGE--WKGPQVSSALNLDTSK-----FAG 5615
            P  + G +   G+  P   +GE G L   G  G     GP     L  DT         G
Sbjct: 1350 PPGRVGPEGLRGIPGP---VGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIG 1406

Query: 5616 GLHFSGPKVEGGVKGGQIGLQAPGLSVSGPQG 5647
             +   GP  E G KG Q GL  PG  V GP G
Sbjct: 1407 LIGLIGPPGEAGEKGDQ-GL--PG--VQGPPG 1433



 Score = 40.4 bits (93), Expect = 0.053
 Identities = 125/457 (27%), Positives = 158/457 (34%), Gaps = 82/457 (17%)

Query: 5206 PKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQL-PSLEG 5264
            P I G+    GL+GP     GP    K P     K G PG   + G      Q  P    
Sbjct: 862  PGIPGEKGLPGLQGPP-GFPGP----KGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPA 916

Query: 5265 DLRGPDVKLE--GPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSM 5322
             + GP  K    GP      PG   P     +P + G +          KG+L    P  
Sbjct: 917  GVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGRE--------GAKGELGPPGPLG 968

Query: 5323 KVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPD-VTLRG-PSLQGDLAVSGDI 5380
            K    GL     G     GG G   P      K + G P  V   G P  +G L  +G I
Sbjct: 969  KEGPAGLR----GFPGPKGGPGDPGP---TGLKGDKGPPGPVGANGSPGERGPLGPAGGI 1021

Query: 5381 KCPKVSVGAPDLSLEASEGSI--KLPKMKLPQFGISTPGSDLHV-NAKGPQVSGELKGPG 5437
              P  S     +     +GS   + P     + GI  P   L    A GP  SGE +G  
Sbjct: 1022 GLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGP--SGE-EGDK 1078

Query: 5438 VDVNLKGPRISA-----------PNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGIGVQ 5486
             DV   G + S            P +      P   G+ GA G    P + G     GV+
Sbjct: 1079 GDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVR 1138

Query: 5487 GLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKG--GLKGSEVGFHGAAPDISVK 5544
            G  G +  PG++       LPG     P G+      KG  G  GS +G HGA      +
Sbjct: 1139 GFVGVIGPPGLQ------GLPG-----PPGE------KGEVGDVGS-MGPHGAPGPRGPQ 1180

Query: 5545 GPAFNMASPESDFGINLKG----PKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGP 5600
            GP  +  +P    G+   G       +G A   G   AP I   +G +  KG  G     
Sbjct: 1181 GPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSG----- 1235

Query: 5601 QVSSALNLDTSKFAGGLHFSGPKVEGGVKG--GQIGL 5635
                      S  AG     GP  E G KG  G  GL
Sbjct: 1236 ---------PSGAAGPPGKKGPPGEDGAKGSVGPTGL 1263



 Score = 37.4 bits (85), Expect = 0.44
 Identities = 69/255 (27%), Positives = 96/255 (37%), Gaps = 44/255 (17%)

Query: 293 GPSLESGDHGKIKFPTMKVPKFGVST-GREGQTPKAGLR----VSAPEVSVGHKGGKPGL 347
           GP  + G+HG    P    P+  + T G +G     G+        P    GH+G     
Sbjct: 638 GPPGQQGNHGSQGLPG---PQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEK 694

Query: 348 TIQAPQLEVSVP----------SANIEGLEGKLKGPQITG-PSLEGDLGLKGAKPQGHIG 396
             Q P      P          ++   GL+G+       G P  +GD+GLKG   QG  G
Sbjct: 695 GAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKG--DQGKPG 752

Query: 397 VDASAPQIGGSITGPSVEVQAPDIDVQG-PGSKLNVPKMKVPKF-SVSGAKGEETGIDVT 454
             A  P+      GP  + QA     +G PGS     K+ VP      G  G +  I   
Sbjct: 753 --APGPRGEDGPEGP--KGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFP 808

Query: 455 LPTGEVTVPGVSGDVSLPEIATGGLEGKMKGTKVKTPEMIIQKPKISMQDVDLSLGSPKL 514
            P G +   G SG    P     GLEG+ +G      E          +    + G P  
Sbjct: 809 GPLGPIGEKGKSGKTGQP-----GLEGE-RGPPGSRGE----------RGQPGATGQPGP 852

Query: 515 KGDI-KVSAPGVQGD 528
           KGD+ +  APG+ G+
Sbjct: 853 KGDVGQDGAPGIPGE 867


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.138    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 272,669,078
Number of Sequences: 37866
Number of extensions: 15498268
Number of successful extensions: 95646
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 12
Number of HSP's successfully gapped in prelim test: 208
Number of HSP's that attempted gapping in prelim test: 25854
Number of HSP's gapped (non-prelim): 3350
length of query: 5890
length of database: 18,247,518
effective HSP length: 125
effective length of query: 5765
effective length of database: 13,514,268
effective search space: 77909755020
effective search space used: 77909755020
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 74 (33.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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