BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|61743954 AHNAK nucleoprotein isoform 1 [Homo sapiens] (5890 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|61743954 AHNAK nucleoprotein isoform 1 [Homo sapiens] 1.200e+04 0.0 gi|156766050 AHNAK nucleoprotein 2 [Homo sapiens] 1613 0.0 gi|116686120 periaxin isoform 2 [Homo sapiens] 266 6e-70 gi|55769541 AHNAK nucleoprotein isoform 2 [Homo sapiens] 234 2e-60 gi|110349719 titin isoform N2-A [Homo sapiens] 94 3e-18 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 79 1e-13 gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 79 1e-13 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 79 1e-13 gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 72 1e-11 gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] 66 9e-10 gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] 66 9e-10 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 66 1e-09 gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo ... 66 1e-09 gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo s... 66 1e-09 gi|154759255 collagen, type XXVIII precursor [Homo sapiens] 65 2e-09 gi|16554449 zonadhesin isoform 3 [Homo sapiens] 61 4e-08 gi|27881494 zonadhesin isoform 6 [Homo sapiens] 61 4e-08 gi|169205253 PREDICTED: hypothetical protein [Homo sapiens] 60 5e-08 gi|224589132 hypothetical protein LOC100132406 [Homo sapiens] 58 2e-07 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 58 2e-07 gi|126352608 elastin isoform e precursor [Homo sapiens] 57 5e-07 gi|126352700 elastin isoform b precursor [Homo sapiens] 57 5e-07 gi|126352440 elastin isoform a precursor [Homo sapiens] 57 7e-07 gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s... 57 7e-07 gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 57 7e-07 gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 57 7e-07 gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s... 57 7e-07 gi|126352322 elastin isoform c precursor [Homo sapiens] 56 9e-07 gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens] 56 9e-07 gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 56 1e-06 >gi|61743954 AHNAK nucleoprotein isoform 1 [Homo sapiens] Length = 5890 Score = 1.200e+04 bits (31150), Expect = 0.0 Identities = 5890/5890 (100%), Positives = 5890/5890 (100%) Query: 1 MEKEETTRELLLPNWQGSGSHGLTIAQRDDGVFVQEVTQNSPAARTGVVKEGDQIVGATI 60 MEKEETTRELLLPNWQGSGSHGLTIAQRDDGVFVQEVTQNSPAARTGVVKEGDQIVGATI Sbjct: 1 MEKEETTRELLLPNWQGSGSHGLTIAQRDDGVFVQEVTQNSPAARTGVVKEGDQIVGATI 60 Query: 61 YFDNLQSGEVTQLLNTMGHHTVGLKLHRKGDRSPEPGQTWTREVFSSCSSEVVLSGDDEE 120 YFDNLQSGEVTQLLNTMGHHTVGLKLHRKGDRSPEPGQTWTREVFSSCSSEVVLSGDDEE Sbjct: 61 YFDNLQSGEVTQLLNTMGHHTVGLKLHRKGDRSPEPGQTWTREVFSSCSSEVVLSGDDEE 120 Query: 121 YQRIYTTKIKPRLKSEDGVEGDLGETQSRTITVTRRVTAYTVDVTGREGAKDIDISSPEF 180 YQRIYTTKIKPRLKSEDGVEGDLGETQSRTITVTRRVTAYTVDVTGREGAKDIDISSPEF Sbjct: 121 YQRIYTTKIKPRLKSEDGVEGDLGETQSRTITVTRRVTAYTVDVTGREGAKDIDISSPEF 180 Query: 181 KIKIPRHELTEISNVDVETQSGKTVIRLPSGSGAASPTGSAVDIRAGAISASGPELQGAG 240 KIKIPRHELTEISNVDVETQSGKTVIRLPSGSGAASPTGSAVDIRAGAISASGPELQGAG Sbjct: 181 KIKIPRHELTEISNVDVETQSGKTVIRLPSGSGAASPTGSAVDIRAGAISASGPELQGAG 240 Query: 241 HSKLQVTMPGIKVGGSGVNVNAKGLDLGGRGGVQVPAVDISSSLGGRAVEVQGPSLESGD 300 HSKLQVTMPGIKVGGSGVNVNAKGLDLGGRGGVQVPAVDISSSLGGRAVEVQGPSLESGD Sbjct: 241 HSKLQVTMPGIKVGGSGVNVNAKGLDLGGRGGVQVPAVDISSSLGGRAVEVQGPSLESGD 300 Query: 301 HGKIKFPTMKVPKFGVSTGREGQTPKAGLRVSAPEVSVGHKGGKPGLTIQAPQLEVSVPS 360 HGKIKFPTMKVPKFGVSTGREGQTPKAGLRVSAPEVSVGHKGGKPGLTIQAPQLEVSVPS Sbjct: 301 HGKIKFPTMKVPKFGVSTGREGQTPKAGLRVSAPEVSVGHKGGKPGLTIQAPQLEVSVPS 360 Query: 361 ANIEGLEGKLKGPQITGPSLEGDLGLKGAKPQGHIGVDASAPQIGGSITGPSVEVQAPDI 420 ANIEGLEGKLKGPQITGPSLEGDLGLKGAKPQGHIGVDASAPQIGGSITGPSVEVQAPDI Sbjct: 361 ANIEGLEGKLKGPQITGPSLEGDLGLKGAKPQGHIGVDASAPQIGGSITGPSVEVQAPDI 420 Query: 421 DVQGPGSKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLE 480 DVQGPGSKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLE Sbjct: 421 DVQGPGSKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLE 480 Query: 481 GKMKGTKVKTPEMIIQKPKISMQDVDLSLGSPKLKGDIKVSAPGVQGDVKGPQVALKGSR 540 GKMKGTKVKTPEMIIQKPKISMQDVDLSLGSPKLKGDIKVSAPGVQGDVKGPQVALKGSR Sbjct: 481 GKMKGTKVKTPEMIIQKPKISMQDVDLSLGSPKLKGDIKVSAPGVQGDVKGPQVALKGSR 540 Query: 541 VDIETPNLEGTLTGPRLGSPSGKTGTCRISMSEVDLNVAAPKVKGGVDVTLPRVEGKVKV 600 VDIETPNLEGTLTGPRLGSPSGKTGTCRISMSEVDLNVAAPKVKGGVDVTLPRVEGKVKV Sbjct: 541 VDIETPNLEGTLTGPRLGSPSGKTGTCRISMSEVDLNVAAPKVKGGVDVTLPRVEGKVKV 600 Query: 601 PEVDVRGPKVDVSAPDVEAHGPEWNLKMPKMKMPTFSTPGAKGEGPDVHMTLPKGDISIS 660 PEVDVRGPKVDVSAPDVEAHGPEWNLKMPKMKMPTFSTPGAKGEGPDVHMTLPKGDISIS Sbjct: 601 PEVDVRGPKVDVSAPDVEAHGPEWNLKMPKMKMPTFSTPGAKGEGPDVHMTLPKGDISIS 660 Query: 661 GPKVNVEAPDVNLEGLGGKLKGPDVKLPDMSVKTPKISMPDVDLHVKGTKVKGEYDVTVP 720 GPKVNVEAPDVNLEGLGGKLKGPDVKLPDMSVKTPKISMPDVDLHVKGTKVKGEYDVTVP Sbjct: 661 GPKVNVEAPDVNLEGLGGKLKGPDVKLPDMSVKTPKISMPDVDLHVKGTKVKGEYDVTVP 720 Query: 721 KLEGELKGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSVPGFKAEGPEVDVNLPKADVDI 780 KLEGELKGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSVPGFKAEGPEVDVNLPKADVDI Sbjct: 721 KLEGELKGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSVPGFKAEGPEVDVNLPKADVDI 780 Query: 781 SGPKIDVTAPDVSIEEPEGKLKGPKFKMPEMNIKVPKISMPDVDLHLKGPNVKGEYDVTM 840 SGPKIDVTAPDVSIEEPEGKLKGPKFKMPEMNIKVPKISMPDVDLHLKGPNVKGEYDVTM Sbjct: 781 SGPKIDVTAPDVSIEEPEGKLKGPKFKMPEMNIKVPKISMPDVDLHLKGPNVKGEYDVTM 840 Query: 841 PKVESEIKVPDVELKSAKMDIDVPDVEVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVN 900 PKVESEIKVPDVELKSAKMDIDVPDVEVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVN Sbjct: 841 PKVESEIKVPDVELKSAKMDIDVPDVEVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVN 900 Query: 901 LPKADVDISGPKVGVEVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGPKV 960 LPKADVDISGPKVGVEVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGPKV Sbjct: 901 LPKADVDISGPKVGVEVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGPKV 960 Query: 961 KGEYDMTVPKLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGPEFDV 1020 KGEYDMTVPKLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGPEFDV Sbjct: 961 KGEYDMTVPKLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGPEFDV 1020 Query: 1021 NLSKANVDISAPKVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKGPK 1080 NLSKANVDISAPKVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKGPK Sbjct: 1021 NLSKANVDISAPKVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKGPK 1080 Query: 1081 MKGNVDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLK 1140 MKGNVDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLK Sbjct: 1081 MKGNVDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLK 1140 Query: 1141 GEGPEVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDV 1200 GEGPEVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDV Sbjct: 1141 GEGPEVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDV 1200 Query: 1201 DLHLKGPKVKGDVDVSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMP 1260 DLHLKGPKVKGDVDVSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMP Sbjct: 1201 DLHLKGPKVKGDVDVSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMP 1260 Query: 1261 KFSMPGFKGEGREVDVNLPKADIDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKA 1320 KFSMPGFKGEGREVDVNLPKADIDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKA Sbjct: 1261 KFSMPGFKGEGREVDVNLPKADIDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKA 1320 Query: 1321 PKISMPDVDLNLKGPKLKGDVDVSLPEVEGEMKVPDVDIKGPKVDISAPDVDVHGPDWHL 1380 PKISMPDVDLNLKGPKLKGDVDVSLPEVEGEMKVPDVDIKGPKVDISAPDVDVHGPDWHL Sbjct: 1321 PKISMPDVDLNLKGPKLKGDVDVSLPEVEGEMKVPDVDIKGPKVDISAPDVDVHGPDWHL 1380 Query: 1381 KMPKVKMPKFSMPGFKGEGPEVDVKLPKADVDVSGPKMDAEVPDVNIEGPDAKLKGPKFK 1440 KMPKVKMPKFSMPGFKGEGPEVDVKLPKADVDVSGPKMDAEVPDVNIEGPDAKLKGPKFK Sbjct: 1381 KMPKVKMPKFSMPGFKGEGPEVDVKLPKADVDVSGPKMDAEVPDVNIEGPDAKLKGPKFK 1440 Query: 1441 MPEMSIKPQKISIPDVGLHLKGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKVDINAPDVE 1500 MPEMSIKPQKISIPDVGLHLKGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKVDINAPDVE Sbjct: 1441 MPEMSIKPQKISIPDVGLHLKGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKVDINAPDVE 1500 Query: 1501 VHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPDVNLEAPEG 1560 VHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPDVNLEAPEG Sbjct: 1501 VHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPDVNLEAPEG 1560 Query: 1561 KLKGPKFKMPSMNIQTHKISMPDVGLNLKAPKLKTDVDVSLPKVEGDLKGPEIDVKAPKM 1620 KLKGPKFKMPSMNIQTHKISMPDVGLNLKAPKLKTDVDVSLPKVEGDLKGPEIDVKAPKM Sbjct: 1561 KLKGPKFKMPSMNIQTHKISMPDVGLNLKAPKLKTDVDVSLPKVEGDLKGPEIDVKAPKM 1620 Query: 1621 DVNVGDIDIEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDMDVSVPKVEG 1680 DVNVGDIDIEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDMDVSVPKVEG Sbjct: 1621 DVNVGDIDIEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDMDVSVPKVEG 1680 Query: 1681 EMKVPDVDIKGPKVDIDAPDVEVHDPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKAD 1740 EMKVPDVDIKGPKVDIDAPDVEVHDPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKAD Sbjct: 1681 EMKVPDVDIKGPKVDIDAPDVEVHDPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKAD 1740 Query: 1741 IDVSGPSVDTDAPDLDIEGPEGKLKGSKFKMPKLNIKAPKVSMPDVDLNLKGPKLKGEID 1800 IDVSGPSVDTDAPDLDIEGPEGKLKGSKFKMPKLNIKAPKVSMPDVDLNLKGPKLKGEID Sbjct: 1741 IDVSGPSVDTDAPDLDIEGPEGKLKGSKFKMPKLNIKAPKVSMPDVDLNLKGPKLKGEID 1800 Query: 1801 ASVPELEGDLRGPQVDVKGPFVEAEVPDVDLECPDAKLKGPKFKMPEMHFKAPKISMPDV 1860 ASVPELEGDLRGPQVDVKGPFVEAEVPDVDLECPDAKLKGPKFKMPEMHFKAPKISMPDV Sbjct: 1801 ASVPELEGDLRGPQVDVKGPFVEAEVPDVDLECPDAKLKGPKFKMPEMHFKAPKISMPDV 1860 Query: 1861 DLHLKGPKVKGDADVSVPKLEGDLTGPSVGVEVPDVELECPDAKLKGPKFKMPDMHFKAP 1920 DLHLKGPKVKGDADVSVPKLEGDLTGPSVGVEVPDVELECPDAKLKGPKFKMPDMHFKAP Sbjct: 1861 DLHLKGPKVKGDADVSVPKLEGDLTGPSVGVEVPDVELECPDAKLKGPKFKMPDMHFKAP 1920 Query: 1921 KISMPDVDLHLKGPKVKGDVDVSVPKLEGDLTGPSVGVEVPDVELECPDAKLKGPKFKMP 1980 KISMPDVDLHLKGPKVKGDVDVSVPKLEGDLTGPSVGVEVPDVELECPDAKLKGPKFKMP Sbjct: 1921 KISMPDVDLHLKGPKVKGDVDVSVPKLEGDLTGPSVGVEVPDVELECPDAKLKGPKFKMP 1980 Query: 1981 EMHFKTPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKMDIDAPDVDVH 2040 EMHFKTPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKMDIDAPDVDVH Sbjct: 1981 EMHFKTPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKMDIDAPDVDVH 2040 Query: 2041 GPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVVVSGPKVDVEVPDVSLEGPEGKL 2100 GPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVVVSGPKVDVEVPDVSLEGPEGKL Sbjct: 2041 GPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVVVSGPKVDVEVPDVSLEGPEGKL 2100 Query: 2101 KGPKLKMPEMHFKAPKISMPDVDLHLKGPKVKGDVDVSLPKLEGDLTGPSVDVEVPDVEL 2160 KGPKLKMPEMHFKAPKISMPDVDLHLKGPKVKGDVDVSLPKLEGDLTGPSVDVEVPDVEL Sbjct: 2101 KGPKLKMPEMHFKAPKISMPDVDLHLKGPKVKGDVDVSLPKLEGDLTGPSVDVEVPDVEL 2160 Query: 2161 ECPDAKLKGPKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMDVSVPKVEGEMKVPDVDI 2220 ECPDAKLKGPKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMDVSVPKVEGEMKVPDVDI Sbjct: 2161 ECPDAKLKGPKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMDVSVPKVEGEMKVPDVDI 2220 Query: 2221 RGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKGEGPEVDVNLPKADVDVSGPKVD 2280 RGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKGEGPEVDVNLPKADVDVSGPKVD Sbjct: 2221 RGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKGEGPEVDVNLPKADVDVSGPKVD 2280 Query: 2281 VEVPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVDVSAPKLEGE 2340 VEVPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVDVSAPKLEGE Sbjct: 2281 VEVPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVDVSAPKLEGE 2340 Query: 2341 LKGPELDVKGPKLDADMPEVAVEGPNGKWKTPKFKMPDMHFKAPKISMPDLDLHLKSPKA 2400 LKGPELDVKGPKLDADMPEVAVEGPNGKWKTPKFKMPDMHFKAPKISMPDLDLHLKSPKA Sbjct: 2341 LKGPELDVKGPKLDADMPEVAVEGPNGKWKTPKFKMPDMHFKAPKISMPDLDLHLKSPKA 2400 Query: 2401 KGEVDVDVPKLEGDLKGPHVDVSGPDIDIEGPEGKLKGPKFKMPDMHFKAPNISMPDVDL 2460 KGEVDVDVPKLEGDLKGPHVDVSGPDIDIEGPEGKLKGPKFKMPDMHFKAPNISMPDVDL Sbjct: 2401 KGEVDVDVPKLEGDLKGPHVDVSGPDIDIEGPEGKLKGPKFKMPDMHFKAPNISMPDVDL 2460 Query: 2461 NLKGPKIKGDVDVSVPEVEGKLEVPDMNIRGPKVDVNAPDVQAPDWHLKMPKMKMPKFSM 2520 NLKGPKIKGDVDVSVPEVEGKLEVPDMNIRGPKVDVNAPDVQAPDWHLKMPKMKMPKFSM Sbjct: 2461 NLKGPKIKGDVDVSVPEVEGKLEVPDMNIRGPKVDVNAPDVQAPDWHLKMPKMKMPKFSM 2520 Query: 2521 PGFKAEGPEVDVNLPKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPKIS 2580 PGFKAEGPEVDVNLPKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPKIS Sbjct: 2521 PGFKAEGPEVDVNLPKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPKIS 2580 Query: 2581 MPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKMPK 2640 MPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKMPK Sbjct: 2581 MPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKMPK 2640 Query: 2641 VKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKLKGPKFKMPEM 2700 VKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKLKGPKFKMPEM Sbjct: 2641 VKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKLKGPKFKMPEM 2700 Query: 2701 NIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGP 2760 NIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGP Sbjct: 2701 NIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGP 2760 Query: 2761 DWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGPEGKWKS 2820 DWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGPEGKWKS Sbjct: 2761 DWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGPEGKWKS 2820 Query: 2821 PKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPEVDLKGPKVDIDV 2880 PKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPEVDLKGPKVDIDV Sbjct: 2821 PKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPEVDLKGPKVDIDV 2880 Query: 2881 PDVNVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDVSGPKVDVEGPDVNIE 2940 PDVNVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDVSGPKVDVEGPDVNIE Sbjct: 2881 PDVNVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDVSGPKVDVEGPDVNIE 2940 Query: 2941 GPEGKLKGPKFKMPEMNIKAPKIPMPDFDLHLKGPKVKGDVDISLPKVEGDLKGPEVDIR 3000 GPEGKLKGPKFKMPEMNIKAPKIPMPDFDLHLKGPKVKGDVDISLPKVEGDLKGPEVDIR Sbjct: 2941 GPEGKLKGPKFKMPEMNIKAPKIPMPDFDLHLKGPKVKGDVDISLPKVEGDLKGPEVDIR 3000 Query: 3001 GPQVDIDVPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDI 3060 GPQVDIDVPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDI Sbjct: 3001 GPQVDIDVPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDI 3060 Query: 3061 DVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDM 3120 DVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDM Sbjct: 3061 DVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDM 3120 Query: 3121 KVPDVDIKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISMPGFKGEGPEVDVNLPKADLD 3180 KVPDVDIKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISMPGFKGEGPEVDVNLPKADLD Sbjct: 3121 KVPDVDIKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISMPGFKGEGPEVDVNLPKADLD 3180 Query: 3181 VSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDLDLNLKGPKMKGEVDVS 3240 VSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDLDLNLKGPKMKGEVDVS Sbjct: 3181 VSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDLDLNLKGPKMKGEVDVS 3240 Query: 3241 LANVEGDLKGPALDIKGPKIDVDAPDIDIHGPDAKLKGPKLKMPDMHVNMPKISMPEIDL 3300 LANVEGDLKGPALDIKGPKIDVDAPDIDIHGPDAKLKGPKLKMPDMHVNMPKISMPEIDL Sbjct: 3241 LANVEGDLKGPALDIKGPKIDVDAPDIDIHGPDAKLKGPKLKMPDMHVNMPKISMPEIDL 3300 Query: 3301 NLKGSKLKGDVDVSGPKLEGDIKAPSLDIKGPEVDVSGPKLNIEGKSKKSRFKLPKFNFS 3360 NLKGSKLKGDVDVSGPKLEGDIKAPSLDIKGPEVDVSGPKLNIEGKSKKSRFKLPKFNFS Sbjct: 3301 NLKGSKLKGDVDVSGPKLEGDIKAPSLDIKGPEVDVSGPKLNIEGKSKKSRFKLPKFNFS 3360 Query: 3361 GSKVQTPEVDVKGKKPDIDITGPKVDINAPDVEVQGKVKGSKFKMPFLSISSPKVSMPDV 3420 GSKVQTPEVDVKGKKPDIDITGPKVDINAPDVEVQGKVKGSKFKMPFLSISSPKVSMPDV Sbjct: 3361 GSKVQTPEVDVKGKKPDIDITGPKVDINAPDVEVQGKVKGSKFKMPFLSISSPKVSMPDV 3420 Query: 3421 ELNLKSPKVKGDLDIAGPNLEGDFKGPKVDIKAPEVNLNAPDVDVHGPDWNLKMPKMKMP 3480 ELNLKSPKVKGDLDIAGPNLEGDFKGPKVDIKAPEVNLNAPDVDVHGPDWNLKMPKMKMP Sbjct: 3421 ELNLKSPKVKGDLDIAGPNLEGDFKGPKVDIKAPEVNLNAPDVDVHGPDWNLKMPKMKMP 3480 Query: 3481 KFSVSGLKAEGPDVAVDLPKGDINIEGPSMNIEGPDLNVEGPEGGLKGPKFKMPDMNIKA 3540 KFSVSGLKAEGPDVAVDLPKGDINIEGPSMNIEGPDLNVEGPEGGLKGPKFKMPDMNIKA Sbjct: 3481 KFSVSGLKAEGPDVAVDLPKGDINIEGPSMNIEGPDLNVEGPEGGLKGPKFKMPDMNIKA 3540 Query: 3541 PKISMPDIDLNLKGPKVKGDVDISLPKLEGDLKGPEVDIKGPKVDINAPDVDVHGPDWHL 3600 PKISMPDIDLNLKGPKVKGDVDISLPKLEGDLKGPEVDIKGPKVDINAPDVDVHGPDWHL Sbjct: 3541 PKISMPDIDLNLKGPKVKGDVDISLPKLEGDLKGPEVDIKGPKVDINAPDVDVHGPDWHL 3600 Query: 3601 KMPKVKMPKFSMPGFKGEGPEVDVTLPKADIDISGPNVDVDVPDVNIEGPDAKLKGPKFK 3660 KMPKVKMPKFSMPGFKGEGPEVDVTLPKADIDISGPNVDVDVPDVNIEGPDAKLKGPKFK Sbjct: 3601 KMPKVKMPKFSMPGFKGEGPEVDVTLPKADIDISGPNVDVDVPDVNIEGPDAKLKGPKFK 3660 Query: 3661 MPEMNIKAPKISMPDFDLNLKGPKMKGDVVVSLPKVEGDLKGPEVDIKGPKVDIDTPDIN 3720 MPEMNIKAPKISMPDFDLNLKGPKMKGDVVVSLPKVEGDLKGPEVDIKGPKVDIDTPDIN Sbjct: 3661 MPEMNIKAPKISMPDFDLNLKGPKMKGDVVVSLPKVEGDLKGPEVDIKGPKVDIDTPDIN 3720 Query: 3721 IEGSEGKFKGPKFKIPEMHLKAPKISMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPEVD 3780 IEGSEGKFKGPKFKIPEMHLKAPKISMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPEVD Sbjct: 3721 IEGSEGKFKGPKFKIPEMHLKAPKISMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPEVD 3780 Query: 3781 IKGPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKV 3840 IKGPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKV Sbjct: 3781 IKGPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKV 3840 Query: 3841 DIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEG 3900 DIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEG Sbjct: 3841 DIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEG 3900 Query: 3901 DMQVPDLDIKGPKVDINAPDVDVRGPDWHLKMPKIKMPKISMPGFKGEGPEVDVNLPKAD 3960 DMQVPDLDIKGPKVDINAPDVDVRGPDWHLKMPKIKMPKISMPGFKGEGPEVDVNLPKAD Sbjct: 3901 DMQVPDLDIKGPKVDINAPDVDVRGPDWHLKMPKIKMPKISMPGFKGEGPEVDVNLPKAD 3960 Query: 3961 LDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVD 4020 LDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVD Sbjct: 3961 LDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVD 4020 Query: 4021 VSLPKMEGDLKAPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEV 4080 VSLPKMEGDLKAPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEV Sbjct: 4021 VSLPKMEGDLKAPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEV 4080 Query: 4081 DVNLPKADIDVSGPKVDIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKG 4140 DVNLPKADIDVSGPKVDIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKG Sbjct: 4081 DVNLPKADIDVSGPKVDIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKG 4140 Query: 4141 PKMKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPG 4200 PKMKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPG Sbjct: 4141 PKMKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPG 4200 Query: 4201 FKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP 4260 FKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP Sbjct: 4201 FKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP 4260 Query: 4261 DFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVK 4320 DFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVK Sbjct: 4261 DFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVK 4320 Query: 4321 MPKFSMPGFKGEGPDVDVTLPKADIEISGPKVDIDAPDVSIEGPDAKLKGPKFKMPEMNI 4380 MPKFSMPGFKGEGPDVDVTLPKADIEISGPKVDIDAPDVSIEGPDAKLKGPKFKMPEMNI Sbjct: 4321 MPKFSMPGFKGEGPDVDVTLPKADIEISGPKVDIDAPDVSIEGPDAKLKGPKFKMPEMNI 4380 Query: 4381 KAPKISMPDIDFNLKGPKVKGDVDVSLPKVEGDLKGPEIDIKGPSLDIDTPDVNIEGPEG 4440 KAPKISMPDIDFNLKGPKVKGDVDVSLPKVEGDLKGPEIDIKGPSLDIDTPDVNIEGPEG Sbjct: 4381 KAPKISMPDIDFNLKGPKVKGDVDVSLPKVEGDLKGPEIDIKGPSLDIDTPDVNIEGPEG 4440 Query: 4441 KLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVESDLKGPEVDIEGPEG 4500 KLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVESDLKGPEVDIEGPEG Sbjct: 4441 KLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVESDLKGPEVDIEGPEG 4500 Query: 4501 KLKGPKFKMPDVHFKSPQISMSDIDLNLKGPKIKGDMDISVPKLEGDLKGPKVDVKGPKV 4560 KLKGPKFKMPDVHFKSPQISMSDIDLNLKGPKIKGDMDISVPKLEGDLKGPKVDVKGPKV Sbjct: 4501 KLKGPKFKMPDVHFKSPQISMSDIDLNLKGPKIKGDMDISVPKLEGDLKGPKVDVKGPKV 4560 Query: 4561 GIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKVKGDMDISLPKVEG 4620 GIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKVKGDMDISLPKVEG Sbjct: 4561 GIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKVKGDMDISLPKVEG 4620 Query: 4621 DLKGPEVDIRDPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKAD 4680 DLKGPEVDIRDPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKAD Sbjct: 4621 DLKGPEVDIRDPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKAD 4680 Query: 4681 IDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMSIKAPKISMPDIDLNLKGPKVKGDVD 4740 IDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMSIKAPKISMPDIDLNLKGPKVKGDVD Sbjct: 4681 IDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMSIKAPKISMPDIDLNLKGPKVKGDVD 4740 Query: 4741 VTLPKVEGDLKGPEADIKGPKVDINTPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDV 4800 VTLPKVEGDLKGPEADIKGPKVDINTPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDV Sbjct: 4741 VTLPKVEGDLKGPEADIKGPKVDINTPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDV 4800 Query: 4801 DVSLPKADIDVSGPKVDVDIPDVNIEGPDAKLKGPKFKMPEINIKAPKISIPDVDLDLKG 4860 DVSLPKADIDVSGPKVDVDIPDVNIEGPDAKLKGPKFKMPEINIKAPKISIPDVDLDLKG Sbjct: 4801 DVSLPKADIDVSGPKVDVDIPDVNIEGPDAKLKGPKFKMPEINIKAPKISIPDVDLDLKG 4860 Query: 4861 PKVKGDFDVSVPKVEGTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPD 4920 PKVKGDFDVSVPKVEGTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPD Sbjct: 4861 PKVKGDFDVSVPKVEGTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPD 4920 Query: 4921 VDLHLKAPKIGFSGPKLEGGEVDLKGPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKF 4980 VDLHLKAPKIGFSGPKLEGGEVDLKGPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKF Sbjct: 4921 VDLHLKAPKIGFSGPKLEGGEVDLKGPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKF 4980 Query: 4981 GFGAKSPKADIKSPSLDVTVPEAELNLETPEISVGGKGKKSKFKMPKIHMSGPKIKAKKQ 5040 GFGAKSPKADIKSPSLDVTVPEAELNLETPEISVGGKGKKSKFKMPKIHMSGPKIKAKKQ Sbjct: 4981 GFGAKSPKADIKSPSLDVTVPEAELNLETPEISVGGKGKKSKFKMPKIHMSGPKIKAKKQ 5040 Query: 5041 GFDLNVPGGEIDASLKAPDVDVNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEFDIKSP 5100 GFDLNVPGGEIDASLKAPDVDVNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEFDIKSP Sbjct: 5041 GFDLNVPGGEIDASLKAPDVDVNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEFDIKSP 5100 Query: 5101 KFKAEAPLPSPKLEGELQAPDLELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGDLK 5160 KFKAEAPLPSPKLEGELQAPDLELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGDLK Sbjct: 5101 KFKAEAPLPSPKLEGELQAPDLELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGDLK 5160 Query: 5161 GPKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPSVGLEGP 5220 GPKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPSVGLEGP Sbjct: 5161 GPKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPSVGLEGP 5220 Query: 5221 DVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSL 5280 DVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSL Sbjct: 5221 DVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSL 5280 Query: 5281 KGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLSGVGGKMQV 5340 KGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLSGVGGKMQV Sbjct: 5281 KGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLSGVGGKMQV 5340 Query: 5341 GGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGS 5400 GGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGS Sbjct: 5341 GGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGS 5400 Query: 5401 IKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPK 5460 IKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPK Sbjct: 5401 IKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPK 5460 Query: 5461 VKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISG 5520 VKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISG Sbjct: 5461 VKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISG 5520 Query: 5521 PEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPD 5580 PEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPD Sbjct: 5521 PEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPD 5580 Query: 5581 ISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQAPGL 5640 ISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQAPGL Sbjct: 5581 ISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQAPGL 5640 Query: 5641 SVSGPQGHLESGSGKVTFPKMKIPKFTFSGRELVGREMGVDVHFPKAEASIQAGAGDGEW 5700 SVSGPQGHLESGSGKVTFPKMKIPKFTFSGRELVGREMGVDVHFPKAEASIQAGAGDGEW Sbjct: 5641 SVSGPQGHLESGSGKVTFPKMKIPKFTFSGRELVGREMGVDVHFPKAEASIQAGAGDGEW 5700 Query: 5701 EESEVKLKKSKIKMPKFNFSKPKGKGGVTGSPEASISGSKGDLKSSKASLGSLEGEAEAE 5760 EESEVKLKKSKIKMPKFNFSKPKGKGGVTGSPEASISGSKGDLKSSKASLGSLEGEAEAE Sbjct: 5701 EESEVKLKKSKIKMPKFNFSKPKGKGGVTGSPEASISGSKGDLKSSKASLGSLEGEAEAE 5760 Query: 5761 ASSPKGKFSLFKSKKPRHRSNSFSDEREFSGPSTPTGTLEFEGGEVSLEGGKVKGKHGKL 5820 ASSPKGKFSLFKSKKPRHRSNSFSDEREFSGPSTPTGTLEFEGGEVSLEGGKVKGKHGKL Sbjct: 5761 ASSPKGKFSLFKSKKPRHRSNSFSDEREFSGPSTPTGTLEFEGGEVSLEGGKVKGKHGKL 5820 Query: 5821 KFGTFGGLGSKSKGHYEVTGSDDETGKLQGSGVSLASKKSRLSSSSSNDSGNKVGIQLPE 5880 KFGTFGGLGSKSKGHYEVTGSDDETGKLQGSGVSLASKKSRLSSSSSNDSGNKVGIQLPE Sbjct: 5821 KFGTFGGLGSKSKGHYEVTGSDDETGKLQGSGVSLASKKSRLSSSSSNDSGNKVGIQLPE 5880 Query: 5881 VELSVSTKKE 5890 VELSVSTKKE Sbjct: 5881 VELSVSTKKE 5890 >gi|156766050 AHNAK nucleoprotein 2 [Homo sapiens] Length = 5795 Score = 1613 bits (4176), Expect = 0.0 Identities = 1483/5261 (28%), Positives = 2327/5261 (44%), Gaps = 1312/5261 (24%) Query: 1075 DLKGPKMKGNVDISAPKIEGEMQVPDVDIRGPKVD--------IKAPDVEGQGLDWSLKI 1126 DLK PK + + P+ E + P RG + D +K +VEG G W + Sbjct: 488 DLKTPKFAFSTE-KEPERERRLSTPQ---RGKRQDASSKAGTGLKGEEVEGAG--W---M 538 Query: 1127 PKMKMPKFSMPSLKGEGPEVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKMP 1186 P + + +G+ + + L + + E D E EG+++ PKFK+P Sbjct: 539 PGREPTTHA--EAQGDEGDGEEGLQRTRIT--------EEQDKGREDTEGQIRMPKFKIP 588 Query: 1187 EM------HFKTPKI-SMPDVDLHLKGP-----------------KVKGDVDVSVPKVEG 1222 + H KT + + D + +G K K D D + Sbjct: 589 SLGWSPSKHTKTGREKATEDTEQGREGEATATADRREQRRTEEGLKDKEDSDSMTNTTKI 648 Query: 1223 EMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMPKF--SMPGFKGEGREVDVNLPK 1280 ++ + +K ++ + EV D KMPK KMP F S PG K VDV+ PK Sbjct: 649 QLIHDEKRLKKEQI---LTEKEVATKDSKFKMPKFKMPLFGASAPG-KSMEASVDVSAPK 704 Query: 1281 ADIDVS--GPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLNLKGPKLK 1338 + DVS + D++ D+S++ P L+ + ++ K P+ +P+ G LK Sbjct: 705 VEADVSLLSMQGDLKTTDLSVQTPSADLE---VQDGQVDVKLPEGPLPE------GASLK 755 Query: 1339 GDVDVSLPEVEG-EMKVPDVDIKGPKVDISAPDVDVHGPDWHLKMPKVKMPKFSMPGFKG 1397 G LP+V+ +K+P VD+KGPK+D+ P +V PD VKM SM Sbjct: 756 GH----LPKVQRPSLKMPKVDLKGPKLDLKGPKAEVTAPD-------VKMSLSSM----- 799 Query: 1398 EGPEVDVKLPKADVDVSGPKMDAEVPDVNIEGPDAKLKGPKFKMPEMSIKPQKISIPDVG 1457 EVDV+ P+A +D + + D + D + D+K K PKFKMP + S+ D Sbjct: 800 ---EVDVQAPRAKLDGARLEGDLSLADKEVTAKDSKFKMPKFKMPSFGVSAPGKSMED-S 855 Query: 1458 LHLKGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKVDINA------------PDVEVHGPD 1505 + + PK++ D V++ ++G++KA D+ I+ P D+ P E GP Sbjct: 856 VDVSAPKVEAD--VSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGPK 913 Query: 1506 WHLKMPKVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPD---------VNLE 1556 HL PKV+MP F MP +GP++D+ PK DL GPK ++ PD V+++ Sbjct: 914 VHL--PKVEMPSFKMPKVDLKGPQIDVKGPKLDL--KGPKAEVTAPDGEVSLPSMEVDVQ 969 Query: 1557 APEGKLKGP------------------KFKMPSMNIQTHKISMPDVGL----NLKAPKLK 1594 A + KL G KFKMP + + +S P + ++ APK+ Sbjct: 970 AQKAKLDGAWLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIKALVDVSAPKV- 1028 Query: 1595 TDVDVSLPKVEGDLKGPEIDVKAPKMDVNV--GDIDIEGPEG-------------KLKGP 1639 + D+SLP ++GDLK ++ ++ D+ V +D++ PEG K++ P Sbjct: 1029 -EADLSLPSMQGDLKTTDLSIQPASTDLKVQADQVDVKLPEGHLPEGAGLKGHLPKVEMP 1087 Query: 1640 KFKMPEMHFKAPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKVDIDAP 1699 FKMP++ K P++ + L LK PK +V+ P VE + +VD++ P +D+ Sbjct: 1088 SFKMPKVALKGPQVDVKGPKLDLKSPKA----EVTAPDVEVSLPSVEVDVEAPGAKLDSA 1143 Query: 1700 DVE----VHDPDWHLKMPKMKMPKFSMPGFKAEGP------EVDVNLPKADIDVSGPSVD 1749 +E + D D K + KMPKF MP F A P VDV+ PK + DVS PS+ Sbjct: 1144 RLEGELSLADKDVTAKDSRFKMPKFKMPSFGASAPGKSIEASVDVSAPKVEADVSLPSMQ 1203 Query: 1750 TDAPDLDI---------------------EG--PEG--------KLKGSKFKMPKLNIKA 1778 D D+ EG PEG K++ KMPK+++K Sbjct: 1204 GDLKTTDLSIQPPSADLEVHAGQVDVKLLEGHVPEGAGFKGHLPKVQMPSLKMPKVDLKG 1263 Query: 1779 PKVSMPDVDLNLKGPKLK---GEIDASVPELEGDLRGPQVDVKGPFVEAEVP--DVDLEC 1833 P+V + L+LKG K + E+ S+P +E D++ P + G ++ ++ D D+ Sbjct: 1264 PQVEVRGPKLDLKGHKAEVTAHEVAVSLPSVEVDMQAPGAKLDGAQLDGDLSLADKDVTA 1323 Query: 1834 PDAKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDADVSVPKLEGDLTGPSVGVEV 1893 D+K K PKFKMP AP S+ + + L PKV +AD+S+P ++GDL + ++ Sbjct: 1324 KDSKFKMPKFKMPSFGVSAPGKSI-EASVDLSAPKV--EADMSLPSMQGDLKTTDLSIQP 1380 Query: 1894 PDVELEC--------------PDA--------KLKGPKFKMPDMHFKAPKISMPDVDLHL 1931 P +LE P+ KL+ P FK+P + K P+I + L L Sbjct: 1381 PSTDLELQAGQLDVKLPEGPVPEGAGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKLDL 1440 Query: 1932 KGPKVK---GDVDVSVPKLEGDLTGPSVGVE---------VPDVELECPDAKLKGPKFKM 1979 K PKV+ DV+VS+P +E D+ P ++ + D +L D+K K PKFKM Sbjct: 1441 KDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGGRLEEDMSLADKDLTTKDSKFKMPKFKM 1500 Query: 1980 PEMHFKTPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKMDID--APDV 2037 P P S+ + + + PKV+ D VS+P ++G++K D+ I+ P D++ A V Sbjct: 1501 PSFGVSAPGKSI-EASVDVSAPKVEAD--VSLPSMQGDLKATDLSIQPPSADLEVQAGQV 1557 Query: 2038 DVHGPDWHLK--------MPKMKMPKFSMPGFKAEGPEVDVNLPKADVVVSGPKVDVEVP 2089 DV P+ + +PK++MP F MP +GP++DV PK D+ GPKV+V P Sbjct: 1558 DVKLPEGPVSEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDL--KGPKVEVTAP 1615 Query: 2090 DVSL---------EGPEGKLKGPKLK-----------MPEMHFKAPKISMPDVDLHLKGP 2129 DV + + P KL G +L+ + FK PK MP + G Sbjct: 1616 DVKMSLSSMEVDVQAPRAKLDGAQLEGDLSLADKAVTAKDSKFKMPKFKMPSFGVSAPGK 1675 Query: 2130 KVKGDVDVSLPKLEGDLTGPSV--DVEVPDVELECPDA---------------------- 2165 ++ VDVS PK+E D++ PS+ D++ D+ ++ P A Sbjct: 1676 SIEASVDVSEPKVEADVSLPSMQGDLKTTDLSIQSPSADLEVQAGQVNVKLPEGPLPEGA 1735 Query: 2166 -------KLKGPKFKMPEMHFKTPKISMPDVNLNLKGPKVK---GDMDVSVPKVEGEMKV 2215 K++ P KMP++ K P++ + L+LKGPK + D++VS+P VE +++ Sbjct: 1736 GFKGHLPKVQMPSLKMPKVALKGPQMDVKGPKLDLKGPKAEVMAPDVEVSLPSVEVDVEA 1795 Query: 2216 PDVDIRGPKV--DIDAPDVDVHGPDWHLKMPKMKMPKF--SMPGFKGEGPEVDVNLPKAD 2271 P + ++ D+ D DV D KMPK KMP F S PG K VDV+ PK + Sbjct: 1796 PGAKLDSVRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPG-KSIEASVDVSAPKVE 1854 Query: 2272 VDVSGPKVD------------------VEVPDVSLEGPEGK------LKG-------PKF 2300 +VS P + V+ V ++ PEG+ LKG P F Sbjct: 1855 AEVSLPSMQGDLKTTDLCIPLPSADLVVQAGQVDMKLPEGQVPEGAGLKGHLPKVDMPSF 1914 Query: 2301 KMPEMHFKTPKISMPDVDFNLKGPKIK---GDVDVSAPKLEGELKGPELDVKGPKLDADM 2357 KMP++ K P+ + +LKGPK + DV+VS P +E +++ + + G +L+ D+ Sbjct: 1915 KMPKVDLKGPQTDVKGAKLDLKGPKAEVTAPDVEVSLPSMEVDVQAQKAKLDGARLEGDL 1974 Query: 2358 P--EVAVEGPNGKWKTPKFKMPDMHFKAP-----------------KISMPDL------- 2391 + + + K+K PKFKMP AP +S+P + Sbjct: 1975 SLADKDMTAKDSKFKMPKFKMPSFGVSAPGRSIEASVDVPAPKVEADVSLPSMQGDLKTT 2034 Query: 2392 DLHLKSPKAK-----GEVDVDVPK--------LEG--------DLKGPHVDVSGPDIDIE 2430 DL ++ P A G+VDV +P+ L+G LK P VD+ GP +DI+ Sbjct: 2035 DLSIQPPSADLKVQTGQVDVKLPEGHVPEGAGLKGHLPKVEMPSLKMPKVDLKGPQVDIK 2094 Query: 2431 GPEGKLKGPKFKM-----------------------------------------PDMHFK 2449 GP+ LK PK +M D FK Sbjct: 2095 GPKLDLKDPKVEMRVPDVEVSLPSMEVDVQAPRAKLDSAHLQGDLTLANKDLTTKDSKFK 2154 Query: 2450 APNISMPDVDLNLKGPKIKGDVDVSVPEVEGKLEVP------------------DMNIRG 2491 P MP ++ G I+ VDVS P+VE + +P D+ ++ Sbjct: 2155 MPKFKMPSFGVSAPGKSIEASVDVSPPKVEADMSLPSMQGDLKTTDLSIQPLSADVKVQA 2214 Query: 2492 PKVDVNAPDVQAPDW-HLK--MPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDI 2548 +VDV + P+ LK +PK++MP F +P +GPE+D+ PK +D+ PKV++ Sbjct: 2215 GQVDVKLLEGPVPEEVGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPK--LDLKDPKVEV 2272 Query: 2549 EGPDV---------NIEGPEGKLKGPKLK-----------MPEMNIKAPKISMPDFDLHL 2588 PDV +++ P KL G +L+ + K PK M F + Sbjct: 2273 TAPDVEVSLPSVEVDVKAPGAKLDGARLEGDMSLADKDVTAKDSKFKMPKFKMLSFGVSA 2332 Query: 2589 KGPKV---------KGDVDVSLPKVEGDLKGPEVDIKGPKVD--INAPDVGVQGPDWHLK 2637 G + K + DVSLP ++GDLK ++ ++ P D + A V V+ P+ + Sbjct: 2333 LGKSIEASADVSALKVEADVSLPSMQGDLKTTDLSVQPPSADLEVQAGQVDVKLPEGPVP 2392 Query: 2638 --------MPKVKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPKVDIEGPDV-------- 2681 +PK++MP F MP +GP DVK PK +D+ GPK D+ PDV Sbjct: 2393 EGAGLKGHLPKLQMPSFKMPKVDLKGPQIDVKGPK--LDLKGPKTDVMAPDVEVSQPSVE 2450 Query: 2682 -NIEGPEGKLKGPKFK-----------MPEMNIKAPKISMPDIDLNLKGPKVKGDVDVSL 2729 ++E P KL G + + K PK MP ++ G ++ VDVS Sbjct: 2451 VDVEAPGAKLDGAWLEGDLSVADKDVTTKDSRFKIPKFKMPSFGVSAPGKSIEASVDVSA 2510 Query: 2730 PKVE---------GDLKGPEVDIKGPKVDID--APDVDVHGPDWHLK--------MPKIK 2770 PKVE GDLK ++ I+ P D++ A VDV P+ + +PK++ Sbjct: 2511 PKVEADGSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGLKGHLPKVQ 2570 Query: 2771 MPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDV---------NIEGPEGKW--- 2818 MP MP +GP +DV PK +D+ GPK +V PDV +++ P K Sbjct: 2571 MPSFKMPEMDLKGPQLDVKGPK--LDLKGPKAEVTAPDVEMSLSSMEVDVQAPRAKLDGA 2628 Query: 2819 ---------------KSPKFKMPEMHFKTPKISMP--DIDLNLTGPKIKGDVDVTGPKVE 2861 K KFKMP+ + ++S P I+ + ++K + D++ P ++ Sbjct: 2629 RLEGDLSLADKGVTAKDSKFKMPKFKMPSFRVSAPGESIEALVDVSELKVEADMSLPSMQ 2688 Query: 2862 GDLKGPEVDLKGPKVDIDVP--DVNVQGPDWHLK--------MPKMKMPKFSMPGFKAEG 2911 GDLK ++ ++ P ++V V+V+ P+ H+ +PK++MP F MP +G Sbjct: 2689 GDLKTTDISIQPPSAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKLQMPSFKMPEVDLKG 2748 Query: 2912 PEVDVNLPKADVDVSGPKVDVEGPDV---------NIEGPEGKLKGPKFK---------- 2952 P++DV P +VD+ GPK +V PDV +++ P KL G + + Sbjct: 2749 PQIDVKGP--NVDLKGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGM 2806 Query: 2953 -MPEMNIKAPKIPMPDFDLHLKGPKVKGDVDIS---------LPKVEGDLKGPEVDIRGP 3002 + K PK MP F + G ++ VD+S P ++GDLK ++ I+ P Sbjct: 2807 TAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSELKVEADGSFPSMQGDLKTTDIRIQPP 2866 Query: 3003 --QVDIDVPDVGVQGPDWHLK--------MPKVKMPKFSMPGFKGEGPDVDVNLPKADLD 3052 Q+++ V V+ P+ H+ +PKV+MP F MP +GP +DV PK LD Sbjct: 2867 SAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPK--LD 2924 Query: 3053 VSGPKVDIDVPDV---------NIEGPEGKLKG-----------------------PKFK 3080 + GPK ++ PDV ++E P KL G PKFK Sbjct: 2925 LKGPKAEVTAPDVEVSLPSVEVDVEAPRAKLDGARLEGDLSLADKDVTAKDSKFKMPKFK 2984 Query: 3081 MPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMKVPDVDIKGP--KVDINAPD 3138 MP + AP S+ ++ +++ PKV+ + VSLP ++GD+K D+ I+ P ++++ A Sbjct: 2985 MPSFGVSAPGKSI-EVSVDVSAPKVEAE--VSLPSMQGDLKTTDISIEPPSAQLEVQAGQ 3041 Query: 3139 VDVQGPDWHLK--------MPKIKMPKISMPGFKGEGPEVDVNLPKADLDVSGPKVDVDV 3190 VD++ P+ H+ +PK++MP MP +GP++DV PK LD+ GPK DV Sbjct: 3042 VDLKLPEGHVPEGAGLKGHLPKLQMPSFKMPKVDRKGPQIDVKGPK--LDLKGPKTDVTA 3099 Query: 3191 PDVNIEGP--------------------------------DAKLKGPKFKMPEMNIKAPK 3218 PDV + P D+K K PKFKMP + AP Sbjct: 3100 PDVEVSQPGMEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPG 3159 Query: 3219 ISMPDLDLNLKGPKMKGEVDVSLANVEGDLKGPALDIKGP--KIDVDAPDIDIHGPD--- 3273 S+ L +++ PK+ E D+SL +++GDLK + I+ P +++V A +D+ P+ Sbjct: 3160 KSIEVL-VDVSAPKV--EADLSLPSMQGDLKNTDISIEPPSAQLEVQAGQVDVKLPEGHV 3216 Query: 3274 ---AKLKG--PKLKMPDMHVNMPKISMPEIDLNLKGSKLKGDVDVSGPKLEGDIKAPSLD 3328 A LKG PKL+MP MPK+ +++KG KL D+ GPK+ D+ AP ++ Sbjct: 3217 LEGAGLKGHLPKLQMPSF--KMPKVDRKGPQIDIKGPKL----DLKGPKM--DVTAPDVE 3268 Query: 3329 IKGP--EVDVSGPKLNIEGK--------------SKKSRFKLPKFNFSGSKVQTP----- 3367 + P EVDV P ++G +K S+FK+PKF + P Sbjct: 3269 VSQPSMEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSYRASAPGKSIQ 3328 Query: 3368 -EVDVKGKKPDIDITGPK-----------VDINAPDVEVQG------------------- 3396 VDV K + D++ P + + + D+EVQ Sbjct: 3329 ASVDVSAPKAEADVSLPSMQGDLKTTDLSIQLPSVDLEVQAGQVDVKLPEGHVPEGAGLK 3388 Query: 3397 ----KVKGSKFKMPFLSISSPKVSMPDVELNLKSPKVK---GDLDIAGPNLEGDFKGP-- 3447 KV+ FKMP + + SP+V + +L+LK PK + D++++ P++E D + P Sbjct: 3389 GHLPKVEMPSFKMPKVDLKSPQVDIKGPKLDLKVPKAEVTVPDVEVSLPSVEVDVQAPRA 3448 Query: 3448 KVDIKAPEVNLNAPDVDVHGPDWNLKMPKMKMPKFSVSG--------LKAEGPDVAVD-- 3497 K+D E +L+ + DV D KMPK KMP F VS L P V D Sbjct: 3449 KLDGARLEGDLSLAEKDVTAKDSKFKMPKFKMPSFGVSAPGRSIEASLDVSAPKVEADVS 3508 Query: 3498 -------LPKGDINIEGPSMNIEGPDLNV-----EGP--EG-GLKG-------PKFKMPD 3535 L D++I+ PS ++E + V EGP EG GLKG P K P Sbjct: 3509 LSSMQGDLKATDLSIQPPSADLEVQAVQVDVELLEGPVPEGAGLKGHLPKVEMPSLKTPK 3568 Query: 3536 MNIKAPKISMPDIDLNLKGPKVK---GDVDISLPKLEGDLKGPEVDIKGPKV--DINAPD 3590 +++K P+I + L+LKGPK + DV++SLP +E D++ P+ + ++ D++ D Sbjct: 3569 VDLKGPQIDVKGPKLDLKGPKAEVRVPDVEVSLPSVEVDVQAPKAKLDAGRLEGDLSLAD 3628 Query: 3591 VDVHGPDWHLKMPKVKMPKF--SMPGFKGEGPEVDVTLPKADIDISGPNV--DVDVPDVN 3646 DV D KMPK KMP F S PG K VDV+ PK + D+S P++ D+ D++ Sbjct: 3629 KDVTAKDSKFKMPKFKMPSFRVSAPG-KSMEASVDVSAPKVEADVSLPSMQGDLKTTDLS 3687 Query: 3647 IEGPDAKLKG------------------------PKFKMPEMNIKAPKISMPDFDLNLKG 3682 I+ P A LK PK +MP ++K PK+ + +++KG Sbjct: 3688 IQPPSADLKVQAGQMDVKLPEGQVPEGAGLKEHLPKVEMP--SLKMPKVDLKGPQVDIKG 3745 Query: 3683 PKMK----------GDVVVSLPKVEGDLKGPEVDIKGPKV--DIDTPDINIEGSEGKFKG 3730 PK+ DV VSLP VE D++ P + ++ D+ D ++ + KFK Sbjct: 3746 PKLDLKVSKAEVTAPDVEVSLPSVEVDVQAPRAKLDSAQLEGDLSLADKDVTAKDSKFKM 3805 Query: 3731 PKFKIPEMHLKAP--------KISMPDIDLNLKGPKVKGDVDVS---------------- 3766 PKFK+P + AP +S P ++ ++ P ++GD+ + Sbjct: 3806 PKFKMPSFGVSAPGKSIEASVHVSAPKVEADVSLPSMQGDLKTTDLSIQPHSADLTVQAR 3865 Query: 3767 --------------------LPKMEG--------DLKGPEVDIKGPKVDINAPDVDVQGP 3798 LPK++ DLKGPE+DIKGPK+D+ P V+V P Sbjct: 3866 QVDMKLLEGHVPEEAGLKGHLPKVQMPSFKMPKVDLKGPEIDIKGPKLDLKDPKVEVTAP 3925 Query: 3799 DWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPEGKLKG 3858 D + +P V +VDV P A LD + + D+ + D ++ + K K Sbjct: 3926 DVEVSLPSV---------------EVDVEAPGAKLDGARLEGDLSLADKDMTAKDSKFKM 3970 Query: 3859 PKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMQVPDLDIKGPKVD--I 3916 PKFKMP + AP SM + +++ PKV + DVSLP ++GD++ DL ++ P D + Sbjct: 3971 PKFKMPSFGVSAPGKSM-EASVDVTAPKV--EADVSLPSMQGDLKATDLSVQPPSADLEV 4027 Query: 3917 NAPDVDVRGPDWHL--------KMPKIKMPKISMPGFKGEGPEVDVNLPKADLDVSGPKV 3968 A VDV+ P+ + +PK++MP MP +GP++DV PK LD+ GPK Sbjct: 4028 QAGQVDVKLPEGPVPEGASLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPK--LDLKGPKA 4085 Query: 3969 DVDVPD---------VNIEGPDAKLKG-----------------------PKFKMPEMNI 3996 +V PD V+++ P AKL G PKFKMP + Sbjct: 4086 EVTAPDVKMSLSSMEVDVQAPRAKLDGVQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGV 4145 Query: 3997 KAPKISMPDFDLHLKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKVDID--APDVDVHGP 4054 AP SM + + ++K DVSLP M+GDLK ++ I+ P D++ A VDV P Sbjct: 4146 SAPGKSM---EASVDVSELKAKADVSLPSMQGDLKTTDLSIQSPSADLEVQAGQVDVKLP 4202 Query: 4055 DWHL--------KMPKVKMPKFSMPGFKGEGPEVDVNLPKADIDVSGPKVDIDTP----- 4101 + L +PKV+MP MP +GP+VDV PK +D+ GPK D+ TP Sbjct: 4203 EGPLPKGAGLKGHLPKVQMPCLKMPKVALKGPQVDVKGPK--LDLKGPKADVMTPVVEVS 4260 Query: 4102 ----DIDIHGP-----------------------EGKLKGPKFKMPDLHLKAPKISMPEV 4134 ++D+ P + K K PKFKMP + AP S + Sbjct: 4261 LPSMEVDVEAPGAKLDSVRLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGKS---I 4317 Query: 4135 DLNLKGPKMKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDVP--DVDVQGPDWHL------ 4186 + +L +K + DVSLP ++GDLK + I+ P D++V DV+ P+ + Sbjct: 4318 EASLDVSALKVEADVSLPSMQGDLKTTHLSIQPPSADLEVQAGQEDVKLPEGPVHEGAGL 4377 Query: 4187 --KMPKVKMPKFSMPGFKGEGPDVDVNLPKADL-----DVSGPKVDIDVP--DVNIEGPD 4237 +PK++MP F +P +GP +DVN+PK DL +V+ P +D+ +P +V+I+ P Sbjct: 4378 KGHLPKLQMPSFKVPKVDLKGPQIDVNVPKLDLKGPKVEVTSPNLDVSLPSMEVDIQAPG 4437 Query: 4238 AKLKGPKFK-----------MPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDL 4286 AKL + + + K PK MP F + G ++ VDVS PK+E D+ Sbjct: 4438 AKLDSTRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGMLSPGKSIEVSVDVSAPKMEADM 4497 Query: 4287 KGPEV--DIKGPKVDIDAP--DVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVTLPK 4342 P + D+K + I AP D++V LK+P+ MP+ + G KG P V++ K Sbjct: 4498 SIPSMQGDLKTTDLRIQAPSADLEVQAGQVDLKLPEGHMPE--VAGLKGHLPKVEMPSFK 4555 Query: 4343 ADIEISGPKVDIDAPDVSIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDFNLKGPKVKGD 4402 PKVD+ P V ++GP LKGPK + AP D Sbjct: 4556 M------PKVDLKGPQVDVKGPKLDLKGPK-----AEVMAP------------------D 4586 Query: 4403 VDVSLPKVEGDLKGPEIDIKGPSL--DIDTPDVNIEGPEGKLKGPKFKMPEMNIKAPKIS 4460 V+VSLP VE D++ P + G L D+ ++ G + K +GPK + K+S Sbjct: 4587 VEVSLPSVETDVQAPGSMLDGARLEGDLSLAHEDVAGKDSKFQGPKLSTSGFEWSSKKVS 4646 Query: 4461 MPDFDLHLKGPKVKGDVDVSLPKVESDLKGPEVDIEGPEGKL------KGPKFKMPDVHF 4514 M + ++G + + P VES + ++ +G L G K +HF Sbjct: 4647 MSSSE--IEGNVTFHEKTSTFPIVESVVHEGDLHDPSRDGNLGLAVGEVGMDSKFKKLHF 4704 Query: 4515 KSPQISMSDIDLNLKGPKIKGDMDISVPKLEGDLKGPKVDVKGPKVGIDTPDIDIHGPEG 4574 K P++S S + K PK D VP G K I I + E Sbjct: 4705 KVPKVSFS----STKTPK-----DSLVP--------------GAKSSIGLSTIPLSSSEC 4741 Query: 4575 KLKGPKFKMPDLH-LKAPKISMPEVDLNLKGPKVKGDMDISLPKVEGDLKGPEVDIRDPK 4633 F++ + P + MP+V +D++ P E + P D+ K Sbjct: 4742 S----SFELQQVSACSEPSMQMPKVGF---AGFPSSRLDLTGPHFESSILSPCEDVTLTK 4794 Query: 4634 VDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKAD--IDVSGPKVDVD 4691 + VP + P+ L++P G D+ LPK + D+ P+ Sbjct: 4795 YQVTVPRAAL-APELALEIP--------------SGSQADIPLPKTECSTDLQPPE---G 4836 Query: 4692 VPDVNIEGPDAKLKG-----------PKFKMPEMSIKAPKISMPDIDLN------LKGPK 4734 VP E L PKF P+ P++++P+ DL+ + P Sbjct: 4837 VPTSQAESHSGPLNSMIPVSLGQVSFPKFYKPKFVFSVPQMAVPEGDLHAAVGAPVMSPL 4896 Query: 4735 VKGD-VDVTLPKVEGD------LKGPEADIKGPKVDINTP------DVDVHGPDWHLKMP 4781 G+ V LP + +GPE + + + P D D G LKMP Sbjct: 4897 SPGERVQCPLPSTQLPSPGTCVSQGPEELVASLQTSVVAPGEAPSEDADHEGKGSPLKMP 4956 Query: 4782 KVKMPKFSMPGFKGEGPDVDVSLPKADIDVS--------GPK--VDVDIPDVNIEGPDAK 4831 K+K+P F K GP VD D +S P+ + +D+P +G + Sbjct: 4957 KIKLPSFRWSPKKETGPKVDPECSVEDSKLSLVLDKDEVAPQSAIHMDLPPER-DGEKGR 5015 Query: 4832 LKGPKFKMPEI---NIKAPK--ISIP--DVDLDLKGPKVKGDF-DVSVPKVEGTLKGPEV 4883 P F MP++ +KA K +S+P DVD L G F D +G G Sbjct: 5016 STKPGFAMPKLALPKMKASKSGVSLPQRDVDPSLSSATAGGSFQDTEKASSDGGRGG--- 5072 Query: 4884 DLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLHLKAPKIGFSGPKLEGGEVD 4943 G G + G +L P + I P +GF+ P L + Sbjct: 5073 --LGATASATGSE----GVNLHRPQVHI----------------PSLGFAKPDLRSSKAK 5110 Query: 4944 LKGPKVEAPSLDVHMDSPDINIEGP-------DVKIPKFKKPKFGFGAKSPKADIKSPSL 4996 + +V P D+ + D++ EG DV + + G G D PS Sbjct: 5111 V---EVSQPEADLPLPKHDLSTEGDSRGCGLGDVPVSQ----PCGEGIAPTPEDPLQPS- 5162 Query: 4997 DVTVPEAE-LNLETPEISVGGK-GKKSKFKMPKIHMSGPKIKAKKQGFDLNVPGGEID-A 5053 P+AE L +E+PE K ++S FKMPK M + + +G G+++ A Sbjct: 5163 -CRKPDAEVLTVESPEEEAMTKYSQESWFKMPKFRMPSLRRSFRDRG-----GAGKLEVA 5216 Query: 5054 SLKAPDVDVNIAGPDAALKVD---VKSPKTKKTMFGKMYFPDVEFDIKSPKFKAEAPLPS 5110 +AP G +AA KV V + M + P+ + ++ + + K+ + Sbjct: 5217 QTQAPAA----TGGEAAAKVKEFLVSGSNVEAAM--SLQLPEADAEVTASESKSSTDI-- 5268 Query: 5111 PKLEGELQAPDLELSLPAIHVEGLDIKAKAPKV---------KMPDVDISVPKIEGDLKG 5161 L +L + L+L L + G ++ ++ +MP + + ++ L G Sbjct: 5269 --LRCDLDSTGLKLHLSTAGMTGDELSTSEVRIHPSKGPLPFQMPGMRLPETQV---LPG 5323 Query: 5162 PKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPS-VGLEGP 5220 + L P ++ ++ K + S S P+ + LK D+PS + + Sbjct: 5324 EIDETPLSKPGHDLASMEDKTEKWS--------SQPEGPLKLKASST--DMPSQISVVNV 5373 Query: 5221 DVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVK-LEGPDVS 5279 D + +KFPK +P+ P PS E D+ P V+ ++ P+ + Sbjct: 5374 DQLWEDSVLTVKFPKLMVPRFSFPA--------------PSSEDDVFIPTVREVQCPEAN 5419 Query: 5280 L------KGPGV---DLPSVNLSMPKVSGPDLDLNLKGPSL 5311 + + PG+ + +P DL+L L+ P + Sbjct: 5420 IDTALCKESPGLWGASILKAGAGVPGEQPVDLNLPLEAPPI 5460 Score = 1605 bits (4155), Expect = 0.0 Identities = 1415/5031 (28%), Positives = 2248/5031 (44%), Gaps = 1216/5031 (24%) Query: 798 EGKLKGPKFKMPEMNIKVPKISMPDVDLHLKGPNVKGEYDVTMPKVESEIKVPDVELKSA 857 + K K PKFKMP P SM + + + P V E DV++ ++ ++K D+ +++ Sbjct: 672 DSKFKMPKFKMPLFGASAPGKSM-EASVDVSAPKV--EADVSLLSMQGDLKTTDLSVQTP 728 Query: 858 KMDIDVPD--VEVQGPDWHLK--------MPKMKMPKFSMPGFKAEGPEVDVNLPKADVD 907 D++V D V+V+ P+ L +PK++ P MP +GP++D+ PKA+V Sbjct: 729 SADLEVQDGQVDVKLPEGPLPEGASLKGHLPKVQRPSLKMPKVDLKGPKLDLKGPKAEVT 788 Query: 908 ISGPKVGVEVPDVNIEGPEGKLKG-----------------------PKFKMPEMNIKAP 944 K+ + +V+++ P KL G PKFKMP + AP Sbjct: 789 APDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKEVTAKDSKFKMPKFKMPSFGVSAP 848 Query: 945 KISMPDVDLHMKGPKVKGEYDMTVPKLEGDLKGPKVDVSAP--DVEMQGPDWNLK----- 997 SM D + + PKV E D+++ ++GDLK + + P D+E+Q ++K Sbjct: 849 GKSMED-SVDVSAPKV--EADVSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGP 905 Query: 998 ----------MPKIKMPKFSMPSLKGEGPEFDVNLSKANVDISAPKVDTNAPD--LSLEG 1045 +PK++MP F MP + +GP+ DV K +D+ PK + APD +SL Sbjct: 906 VPEGAGPKVHLPKVEMPSFKMPKVDLKGPQIDVKGPK--LDLKGPKAEVTAPDGEVSLPS 963 Query: 1046 PEGKLKGPKFKM------------------PEMHFRAPKMSLPDVDLDLKGPKMKGNVDI 1087 E ++ K K+ + F+ PK +P + G +K VD+ Sbjct: 964 MEVDVQAQKAKLDGAWLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIKALVDV 1023 Query: 1088 SAPKIEGEMQVP------------------DVDIRGPKVDIKAPD---VEGQGLDWSLKI 1126 SAPK+E ++ +P D+ ++ +VD+K P+ EG GL L Sbjct: 1024 SAPKVEADLSLPSMQGDLKTTDLSIQPASTDLKVQADQVDVKLPEGHLPEGAGLKGHL-- 1081 Query: 1127 PKMKMPKFSMPSLKGEGPEVDVNLPKADVVVSGPKVDIEAPD---------VSLEGPEGK 1177 PK++MP F MP + +GP+VDV PK D + PK ++ APD V +E P K Sbjct: 1082 PKVEMPSFKMPKVALKGPQVDVKGPKLD--LKSPKAEVTAPDVEVSLPSVEVDVEAPGAK 1139 Query: 1178 LKGPKFK-----------MPEMHFKTPKISMPDVDLHLKGPKVKGDVDVSVPKVE----- 1221 L + + + FK PK MP G ++ VDVS PKVE Sbjct: 1140 LDSARLEGELSLADKDVTAKDSRFKMPKFKMPSFGASAPGKSIEASVDVSAPKVEADVSL 1199 Query: 1222 ----GEMKVPDVEIKGPKMDID--APDVEVQGPDWH------------------LKMPKM 1257 G++K D+ I+ P D++ A V+V+ + H LKMPK+ Sbjct: 1200 PSMQGDLKTTDLSIQPPSADLEVHAGQVDVKLLEGHVPEGAGFKGHLPKVQMPSLKMPKV 1259 Query: 1258 KM---------PKFSMPGFKGE--GREVDVNLPKADIDVSGPKV---------DVEVPDV 1297 + PK + G K E EV V+LP ++D+ P D+ + D Sbjct: 1260 DLKGPQVEVRGPKLDLKGHKAEVTAHEVAVSLPSVEVDMQAPGAKLDGAQLDGDLSLADK 1319 Query: 1298 SLEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLNLKGPKLKGDVDVSLPEVEGEMKVPDV 1357 + + K K PKFKMP AP S+ + ++L PK+ + D+SLP ++G++K D+ Sbjct: 1320 DVTAKDSKFKMPKFKMPSFGVSAPGKSI-EASVDLSAPKV--EADMSLPSMQGDLKTTDL 1376 Query: 1358 DIKGPKVD--ISAPDVDVHGPDWHL--------KMPKVKMPKFSMPGFKGEGPEVDVKLP 1407 I+ P D + A +DV P+ + +PK++MP F +P +GPE+D+K P Sbjct: 1377 SIQPPSTDLELQAGQLDVKLPEGPVPEGAGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGP 1436 Query: 1408 KAD-----VDVSGPKMDAEVP--DVNIEGPDAKLKG-----------------------P 1437 K D V+V+ P ++ +P +V++E P AKL G P Sbjct: 1437 KLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGGRLEEDMSLADKDLTTKDSKFKMP 1496 Query: 1438 KFKMPEMSIKPQKISIPDVGLHLKGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKVD--IN 1495 KFKMP + SI + + + PK++ DV++P ++G++KA D+ I+ P D + Sbjct: 1497 KFKMPSFGVSAPGKSI-EASVDVSAPKVEA--DVSLPSMQGDLKATDLSIQPPSADLEVQ 1553 Query: 1496 APDVEVHGPDWHLK--------MPKVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKVD 1547 A V+V P+ + +PKV+MP F MP +GP++D+ PK DL GPKV+ Sbjct: 1554 AGQVDVKLPEGPVSEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDL--KGPKVE 1611 Query: 1548 IDVPD---------VNLEAPEGKLKG------------------PKFKMPSMNIQTHKIS 1580 + PD V+++AP KL G KFKMP + + +S Sbjct: 1612 VTAPDVKMSLSSMEVDVQAPRAKLDGAQLEGDLSLADKAVTAKDSKFKMPKFKMPSFGVS 1671 Query: 1581 MP--DVGLNLKAPKLKTDVDVSLPKVEGDLKGPEIDVKAPKMDVNV--GDIDIEGPEG-- 1634 P + ++ + K + DVSLP ++GDLK ++ +++P D+ V G ++++ PEG Sbjct: 1672 APGKSIEASVDVSEPKVEADVSLPSMQGDLKTTDLSIQSPSADLEVQAGQVNVKLPEGPL 1731 Query: 1635 -----------KLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVK---GDMDVSVPKVEG 1680 K++ P KMP++ K P++ + L LKGPK + D++VS+P VE Sbjct: 1732 PEGAGFKGHLPKVQMPSLKMPKVALKGPQMDVKGPKLDLKGPKAEVMAPDVEVSLPSVEV 1791 Query: 1681 EMKVPDVDIKGPKV--DIDAPDVEVHDPDWHLKMPKMKMPKF--SMPGFKAEGPEVDVNL 1736 +++ P + ++ D+ D +V D KMPK KMP F S PG E VDV+ Sbjct: 1792 DVEAPGAKLDSVRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEA-SVDVSA 1850 Query: 1737 PKADIDVSGPSVDTD------------------APDLDIEGPEGK------LKG------ 1766 PK + +VS PS+ D A +D++ PEG+ LKG Sbjct: 1851 PKVEAEVSLPSMQGDLKTTDLCIPLPSADLVVQAGQVDMKLPEGQVPEGAGLKGHLPKVD 1910 Query: 1767 -SKFKMPKLNIKAPKVSMPDVDLNLKGPKLK---GEIDASVPELEGDLRGPQVDVKGPFV 1822 FKMPK+++K P+ + L+LKGPK + +++ S+P +E D++ + + G + Sbjct: 1911 MPSFKMPKVDLKGPQTDVKGAKLDLKGPKAEVTAPDVEVSLPSMEVDVQAQKAKLDGARL 1970 Query: 1823 EAE--VPDVDLECPDAKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDADVSVPKL 1880 E + + D D+ D+K K PKFKMP AP S+ + + + PKV +ADVS+P + Sbjct: 1971 EGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGRSI-EASVDVPAPKV--EADVSLPSM 2027 Query: 1881 EGDLTGPSVGVEVP---------DVELECPD------AKLKG-------PKFKMPDMHFK 1918 +GDL + ++ P V+++ P+ A LKG P KMP + K Sbjct: 2028 QGDLKTTDLSIQPPSADLKVQTGQVDVKLPEGHVPEGAGLKGHLPKVEMPSLKMPKVDLK 2087 Query: 1919 APKISMPDVDLHLKGPKVK---GDVDVSVPKLEGDLTGPSVGVE---------VPDVELE 1966 P++ + L LK PKV+ DV+VS+P +E D+ P ++ + + +L Sbjct: 2088 GPQVDIKGPKLDLKDPKVEMRVPDVEVSLPSMEVDVQAPRAKLDSAHLQGDLTLANKDLT 2147 Query: 1967 CPDAKLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIK 2026 D+K K PKFKMP P S+ + + + PKV+ DM S+P ++G++K D+ I+ Sbjct: 2148 TKDSKFKMPKFKMPSFGVSAPGKSI-EASVDVSPPKVEADM--SLPSMQGDLKTTDLSIQ 2204 Query: 2027 GPKMD--IDAPDVDV---HGP---DWHLK--MPKMKMPKFSMPGFKAEGPEVDVNLPKAD 2076 D + A VDV GP + LK +PK++MP F +P +GPE+D+ PK D Sbjct: 2205 PLSADVKVQAGQVDVKLLEGPVPEEVGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKLD 2264 Query: 2077 -----VVVSGPKVDVEVP--DVSLEGPEGKLKGPKLK-----------MPEMHFKAPKIS 2118 V V+ P V+V +P +V ++ P KL G +L+ + FK PK Sbjct: 2265 LKDPKVEVTAPDVEVSLPSVEVDVKAPGAKLDGARLEGDMSLADKDVTAKDSKFKMPKFK 2324 Query: 2119 MPDVDLHLKGPKV---------KGDVDVSLPKLEGDL-------TGPSVDVEVP--DVEL 2160 M + G + K + DVSLP ++GDL PS D+EV V++ Sbjct: 2325 MLSFGVSALGKSIEASADVSALKVEADVSLPSMQGDLKTTDLSVQPPSADLEVQAGQVDV 2384 Query: 2161 ECPDA-------------KLKGPKFKMPEMHFKTPKISMPDVNLNLKGPK---VKGDMDV 2204 + P+ KL+ P FKMP++ K P+I + L+LKGPK + D++V Sbjct: 2385 KLPEGPVPEGAGLKGHLPKLQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKTDVMAPDVEV 2444 Query: 2205 SVPKVEGEMKVPDVDIRGP--KVDIDAPDVDVHGPDWHLKMPKMKMPKF--SMPGFKGEG 2260 S P VE +++ P + G + D+ D DV D K+PK KMP F S PG K Sbjct: 2445 SQPSVEVDVEAPGAKLDGAWLEGDLSVADKDVTTKDSRFKIPKFKMPSFGVSAPG-KSIE 2503 Query: 2261 PEVDVNLPK-------------------------ADVDVSGPKVDVEVPD------VSLE 2289 VDV+ PK AD++V +VDV++P+ L+ Sbjct: 2504 ASVDVSAPKVEADGSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGLK 2563 Query: 2290 GPEGKLKGPKFKMPEMHFKTPKISMPDVDFNLKGPKIK---GDVDVSAPKLEGELKGPEL 2346 G K++ P FKMPEM K P++ + +LKGPK + DV++S +E +++ P Sbjct: 2564 GHLPKVQMPSFKMPEMDLKGPQLDVKGPKLDLKGPKAEVTAPDVEMSLSSMEVDVQAPRA 2623 Query: 2347 DVKGPKLDAD--MPEVAVEGPNGKWKTPKFKMPDMHFKAP-----------------KIS 2387 + G +L+ D + + V + K+K PKFKMP AP +S Sbjct: 2624 KLDGARLEGDLSLADKGVTAKDSKFKMPKFKMPSFRVSAPGESIEALVDVSELKVEADMS 2683 Query: 2388 MPDL-------DLHLKSPKAK-----GEVDVDVPK--------LEG-------------- 2413 +P + D+ ++ P A+ G+VDV +P+ L+G Sbjct: 2684 LPSMQGDLKTTDISIQPPSAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKLQMPSFKMPE 2743 Query: 2414 -DLKGPHVDVSGPDIDIEGPEGKLKGPKFKM----------------------------- 2443 DLKGP +DV GP++D++GP+ ++ P KM Sbjct: 2744 VDLKGPQIDVKGPNVDLKGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLAD 2803 Query: 2444 -----PDMHFKAPNISMPDVDLNLKGPKIKGDVDV---------SVPEVEGKLEVPDMNI 2489 D FK P MP ++ G I+ VDV S P ++G L+ D+ I Sbjct: 2804 KGMTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSELKVEADGSFPSMQGDLKTTDIRI 2863 Query: 2490 RGP----KVDVNAPDVQAPDWHL--------KMPKMKMPKFSMPGFKAEGPEVDVNLPKA 2537 + P +V DV+ P+ H+ +PK++MP F MP +GP++DV PK Sbjct: 2864 QPPSAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPK- 2922 Query: 2538 DVDISGPKVDIEGPD---------VNIEGPEGKLKGPKLK-----------MPEMNIKAP 2577 +D+ GPK ++ PD V++E P KL G +L+ + K P Sbjct: 2923 -LDLKGPKAEVTAPDVEVSLPSVEVDVEAPRAKLDGARLEGDLSLADKDVTAKDSKFKMP 2981 Query: 2578 KISMPDFDLHLKGPKVKGDVDVSLPKVE---------GDLKGPEVDIKGP--KVDINAPD 2626 K MP F + G ++ VDVS PKVE GDLK ++ I+ P ++++ A Sbjct: 2982 KFKMPSFGVSAPGKSIEVSVDVSAPKVEAEVSLPSMQGDLKTTDISIEPPSAQLEVQAGQ 3041 Query: 2627 VGVQGPDWHL--------KMPKVKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPKVDIEG 2678 V ++ P+ H+ +PK++MP F MP +GP DVK PK +D+ GPK D+ Sbjct: 3042 VDLKLPEGHVPEGAGLKGHLPKLQMPSFKMPKVDRKGPQIDVKGPK--LDLKGPKTDVTA 3099 Query: 2679 PDVNIEGP--------------------------------EGKLKGPKFKMPEMNIKAPK 2706 PDV + P + K K PKFKMP + AP Sbjct: 3100 PDVEVSQPGMEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPG 3159 Query: 2707 ISMPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGP--KVDIDAPDVDVHGPDWHL 2764 S+ ++ +++ PKV + D+SLP ++GDLK ++ I+ P ++++ A VDV P+ H+ Sbjct: 3160 KSI-EVLVDVSAPKV--EADLSLPSMQGDLKNTDISIEPPSAQLEVQAGQVDVKLPEGHV 3216 Query: 2765 --------KMPKIKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGP-- 2814 +PK++MP MP +GP +D+ PK +D+ GPK+DV PDV + P Sbjct: 3217 LEGAGLKGHLPKLQMPSFKMPKVDRKGPQIDIKGPK--LDLKGPKMDVTAPDVEVSQPSM 3274 Query: 2815 ------------------------------EGKWKSPKFKMPEMHFKTPKISMPDIDLNL 2844 + K+K PKFKMP P S+ +++ Sbjct: 3275 EVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSYRASAPGKSI-QASVDV 3333 Query: 2845 TGPKIKGDVDVTGPKVEGDLKGPEVDLKGPKVDIDVP--DVNVQGPDWHL--------KM 2894 + PK + DV + P ++GDLK ++ ++ P VD++V V+V+ P+ H+ + Sbjct: 3334 SAPKAEADVSL--PSMQGDLKTTDLSIQLPSVDLEVQAGQVDVKLPEGHVPEGAGLKGHL 3391 Query: 2895 PKMKMPKFSMPGFKAEGPEVDVNLPKADVDVSGPKVDVEGPD---------VNIEGPEGK 2945 PK++MP F MP + P+VD+ PK D+ V PK +V PD V+++ P K Sbjct: 3392 PKVEMPSFKMPKVDLKSPQVDIKGPKLDLKV--PKAEVTVPDVEVSLPSVEVDVQAPRAK 3449 Query: 2946 LKGPKFK-----------MPEMNIKAPKIPMPDFDLHLKGPKVKGDVDISLPKVE----- 2989 L G + + + K PK MP F + G ++ +D+S PKVE Sbjct: 3450 LDGARLEGDLSLAEKDVTAKDSKFKMPKFKMPSFGVSAPGRSIEASLDVSAPKVEADVSL 3509 Query: 2990 ----GDLKGPEVDIRGPQVDIDVPDVGV----------QGPDWHLKMPKVKMPKFSMPGF 3035 GDLK ++ I+ P D++V V V +G +PKV+MP P Sbjct: 3510 SSMQGDLKATDLSIQPPSADLEVQAVQVDVELLEGPVPEGAGLKGHLPKVEMPSLKTPKV 3569 Query: 3036 KGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGP------------------------- 3070 +GP +DV PK LD+ GPK ++ VPDV + P Sbjct: 3570 DLKGPQIDVKGPK--LDLKGPKAEVRVPDVEVSLPSVEVDVQAPKAKLDAGRLEGDLSLA 3627 Query: 3071 -------EGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMKVP 3123 + K K PKFKMP + AP SM + +++ PKV + DVSLP ++GD+K Sbjct: 3628 DKDVTAKDSKFKMPKFKMPSFRVSAPGKSM-EASVDVSAPKV--EADVSLPSMQGDLKTT 3684 Query: 3124 DVDIKGPKVD--INAPDVDVQGPDWHL--------KMPKIKMPKISMPGFKGEGPEVDVN 3173 D+ I+ P D + A +DV+ P+ + +PK++MP + MP +GP+VD+ Sbjct: 3685 DLSIQPPSADLKVQAGQMDVKLPEGQVPEGAGLKEHLPKVEMPSLKMPKVDLKGPQVDIK 3744 Query: 3174 LPKADL-----DVSGPKVDVDVPDVNIE-------------------------GPDAKLK 3203 PK DL +V+ P V+V +P V ++ D+K K Sbjct: 3745 GPKLDLKVSKAEVTAPDVEVSLPSVEVDVQAPRAKLDSAQLEGDLSLADKDVTAKDSKFK 3804 Query: 3204 GPKFKMPEMNIKAPKISMPDLDLNLKGPKMKGEVDVSLANVEGDLKGPALDIKGPKID-- 3261 PKFKMP + AP S+ + +++ PK+ E DVSL +++GDLK L I+ D Sbjct: 3805 MPKFKMPSFGVSAPGKSI-EASVHVSAPKV--EADVSLPSMQGDLKTTDLSIQPHSADLT 3861 Query: 3262 VDAPDIDI-----HGP-DAKLKG--PKLKMPDMHVNMPKISMPEIDLNLKGSKL------ 3307 V A +D+ H P +A LKG PK++MP MPK+ + ++++KG KL Sbjct: 3862 VQARQVDMKLLEGHVPEEAGLKGHLPKVQMPSF--KMPKVDLKGPEIDIKGPKLDLKDPK 3919 Query: 3308 ----KGDVDVSGPKLEGDIKAPSLDIKGPEVDVSGPKLNIEGKSKKSRFKLPKFNFSGSK 3363 DV+VS P +E D++AP + G ++ + + +K S+FK+PKF Sbjct: 3920 VEVTAPDVEVSLPSVEVDVEAPGAKLDGARLEGDLSLADKDMTAKDSKFKMPKFKMPSFG 3979 Query: 3364 VQTPEVDVKGKKPDIDITGPKVDINAPDVEVQGKVKGSKFKMPFLSISSPKVSMPDVELN 3423 V P K + +D+T PKV+ + +QG +K + V P +L Sbjct: 3980 VSAPG---KSMEASVDVTAPKVEADVSLPSMQGDLKATDL----------SVQPPSADLE 4026 Query: 3424 LKSPKVKGDLDIAGPNLEG-DFKG--PKVDI---KAPEVNLNAPDVDVHGPDWNLKMPKM 3477 +++ +V L GP EG KG PKV + K P+V+L P +DV GP +LK PK Sbjct: 4027 VQAGQVDVKLP-EGPVPEGASLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKA 4085 Query: 3478 KMPKFSVSGLKAEGPDVAVDLPKGDINIEGPSMNIEG---------PDLNVEGPEGGLKG 3528 ++ PDV + L +++++ P ++G D +V + K Sbjct: 4086 EV----------TAPDVKMSLSSMEVDVQAPRAKLDGVQLEGDLSLADKDVTAKDSKFKM 4135 Query: 3529 PKFKMPDMNIKAPKISMPDIDLNLKGPKVKGDVDISLPKLEGDLKGPEVDIKGPKVD--I 3586 PKFKMP + AP SM + ++ ++K D+SLP ++GDLK ++ I+ P D + Sbjct: 4136 PKFKMPSFGVSAPGKSM---EASVDVSELKAKADVSLPSMQGDLKTTDLSIQSPSADLEV 4192 Query: 3587 NAPDVDVHGPDWHL--------KMPKVKMPKFSMPGFKGEGPEVDVTLPKADI-----DI 3633 A VDV P+ L +PKV+MP MP +GP+VDV PK D+ D+ Sbjct: 4193 QAGQVDVKLPEGPLPKGAGLKGHLPKVQMPCLKMPKVALKGPQVDVKGPKLDLKGPKADV 4252 Query: 3634 SGPNVDVDVP--DVNIEGP-----------------------DAKLKGPKFKMPEMNIKA 3668 P V+V +P +V++E P D+K K PKFKMP + A Sbjct: 4253 MTPVVEVSLPSMEVDVEAPGAKLDSVRLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSA 4312 Query: 3669 PKISMPDFDLNLKGPKMKGDVVVSLPKVEGDLKGPEVDIKGPKVDIDT------------ 3716 P S+ + L++ K++ D VSLP ++GDLK + I+ P D++ Sbjct: 4313 PGKSI-EASLDVSALKVEAD--VSLPSMQGDLKTTHLSIQPPSADLEVQAGQEDVKLPEG 4369 Query: 3717 ---PDINIEGSEGKFKGPKFKIPEMHLKAPKISMPDIDLNLKGPKVK---GDVDVSLPKM 3770 ++G K + P FK+P++ LK P+I + L+LKGPKV+ ++DVSLP M Sbjct: 4370 PVHEGAGLKGHLPKLQMPSFKVPKVDLKGPQIDVNVPKLDLKGPKVEVTSPNLDVSLPSM 4429 Query: 3771 EGDLKGPEVDIKGPKV--DINAPDVDVQGPDWHLKMPKVKMPKFSM--PGFKGEGPDVDV 3826 E D++ P + ++ D++ D DV D KMPK KMP F M PG K VDV Sbjct: 4430 EVDIQAPGAKLDSTRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGMLSPG-KSIEVSVDV 4488 Query: 3827 NLPKADLDVSGPKV--DIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKG 3884 + PK + D+S P + D+ D+ I+ P L + + ++++K P+ MP++ LKG Sbjct: 4489 SAPKMEADMSIPSMQGDLKTTDLRIQAPSADL---EVQAGQVDLKLPEGHMPEV-AGLKG 4544 Query: 3885 PKVKGDM-DVSLPKVEGDMQVPDLDIKGPKVDINAPDVDVRGPDWHLKMPKIKMPKISMP 3943 K +M +PKV D++ P +D+KGPK+D+ P +V PD + +P + Sbjct: 4545 HLPKVEMPSFKMPKV--DLKGPQVDVKGPKLDLKGPKAEVMAPDVEVSLPSV-------- 4594 Query: 3944 GFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISM 4003 E DV P + LD + + D+ + ++ G D+K +GPK + K+SM Sbjct: 4595 -------ETDVQAPGSMLDGARLEGDLSLAHEDVAGKDSKFQGPKLSTSGFEWSSKKVSM 4647 Query: 4004 PDFDLH-----------------------LKGPKVKGDVDVSLPKMEGDLKAPEVDIKGP 4040 ++ L P G++ +++ ++ D K ++ K P Sbjct: 4648 SSSEIEGNVTFHEKTSTFPIVESVVHEGDLHDPSRDGNLGLAVGEVGMDSKFKKLHFKVP 4707 Query: 4041 KVDIDA----PDVDVHGPDWHLKM-----------------------PKVKMPKFSMPGF 4073 KV + D V G + + P ++MPK GF Sbjct: 4708 KVSFSSTKTPKDSLVPGAKSSIGLSTIPLSSSECSSFELQQVSACSEPSMQMPKVGFAGF 4767 Query: 4074 KGE--------------GPEVDVNLPKADIDV--------------SGPKVDIDTP---- 4101 P DV L K + V SG + DI P Sbjct: 4768 PSSRLDLTGPHFESSILSPCEDVTLTKYQVTVPRAALAPELALEIPSGSQADIPLPKTEC 4827 Query: 4102 DIDIHGPE----------------------GKLKGPKFKMPDLHLKAPKISMPEVDLN-- 4137 D+ PE G++ PKF P P++++PE DL+ Sbjct: 4828 STDLQPPEGVPTSQAESHSGPLNSMIPVSLGQVSFPKFYKPKFVFSVPQMAVPEGDLHAA 4887 Query: 4138 ----LKGPKMKGD-VDVSLPKVEGD------LKGPEVDIKGPKVDIDVP------DVDVQ 4180 + P G+ V LP + +GPE + + + P D D + Sbjct: 4888 VGAPVMSPLSPGERVQCPLPSTQLPSPGTCVSQGPEELVASLQTSVVAPGEAPSEDADHE 4947 Query: 4181 GPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVS--------GPK--VDIDVPD 4230 G LKMPK+K+P F K GP VD D +S P+ + +D+P Sbjct: 4948 GKGSPLKMPKIKLPSFRWSPKKETGPKVDPECSVEDSKLSLVLDKDEVAPQSAIHMDLPP 5007 Query: 4231 VNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPE 4290 +G + P F MP++ + K S L P+ D +S G + E Sbjct: 5008 ER-DGEKGRSTKPGFAMPKLALPKMKASKSGVSL----PQRDVDPSLSSATAGGSFQDTE 5062 Query: 4291 -VDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPK--FSMPGFKGEGPDVDVTLPKADIEI 4347 G + + A +L P+V +P F+ P D+ KA +E+ Sbjct: 5063 KASSDGGRGGLGATASATGSEGVNLHRPQVHIPSLGFAKP---------DLRSSKAKVEV 5113 Query: 4348 SGPKVDIDAP--DVSIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDFNLKGPKVKGDVDV 4405 S P+ D+ P D+S EG D++ G GDV V Sbjct: 5114 SQPEADLPLPKHDLSTEG-DSRGCG-----------------------------LGDVPV 5143 Query: 4406 SLPKVEGDLKGPEIDIKGPSLDIDTPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDFD 4465 S P EG PE ++ D + +E PE + K+ E K PK MP Sbjct: 5144 SQPCGEGIAPTPEDPLQPSCRKPDAEVLTVESPEEEAM-TKYSQ-ESWFKMPKFRMPSLR 5201 Query: 4466 LHLKGPKVKGDVDVSLPKVESDLKGPEVDIEGPEGKLKGPKFKMPDVHFKSPQISMSDID 4525 + G ++V+ + + G E K +F +S S+++ Sbjct: 5202 RSFRDRGGAGKLEVAQTQAPA--------ATGGEAAAKVKEF----------LVSGSNVE 5243 Query: 4526 --LNLKGPKIKGDMDISVPKLEGDLKGPKVDVKGPKV----------GIDTPDIDIHGPE 4573 ++L+ P+ ++ S K D+ +D G K+ + T ++ IH + Sbjct: 5244 AAMSLQLPEADAEVTASESKSSTDILRCDLDSTGLKLHLSTAGMTGDELSTSEVRIHPSK 5303 Query: 4574 GKLKGPKFKMPDLHLKAPKISMPEVD---LNLKGPKVKGDMDISLPKVEGDLKGP---EV 4627 G L F+MP + L ++ E+D L+ G + M+ K +GP + Sbjct: 5304 GPL---PFQMPGMRLPETQVLPGEIDETPLSKPGHDL-ASMEDKTEKWSSQPEGPLKLKA 5359 Query: 4628 DIRDPKVDIDVPDVDVQGPDWHL--KMPKVKMPKFSMPGFKGEG----PDV-DVNLPKAD 4680 D I V +VD D L K PK+ +P+FS P E P V +V P+A+ Sbjct: 5360 SSTDMPSQISVVNVDQLWEDSVLTVKFPKLMVPRFSFPAPSSEDDVFIPTVREVQCPEAN 5419 Query: 4681 IDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMSIKAPKISMPDIDLNLKGPKVKGDVD 4740 ID + K + +I A + G + + ++AP IS + ++++G +V+ + Sbjct: 5420 IDTALCKESPGLWGASILKAGAGVPGEQPVDLNLPLEAPPIS--KVRVHIQGAQVESQ-E 5476 Query: 4741 VTLPKVEG----DLKGPEADIKGPKVDINTPDVDVHGPDWHLKMPKVKMPK 4787 VT+ + DL P + P ++ P + + KVK+P+ Sbjct: 5477 VTIHSIVTPEFVDLSVPRTFSTQIVRESEIPTSEIQTPSYGFSLLKVKIPE 5527 Score = 1587 bits (4110), Expect = 0.0 Identities = 1411/4892 (28%), Positives = 2176/4892 (44%), Gaps = 1192/4892 (24%) Query: 1559 EGKLKGPKFKMPSMNIQTHKISMPDVGLNLKAPKLKTDVDVSLPKVEGDLKGPEIDVKAP 1618 + K K PKFKMP SM + +++ APK+ + DVSL ++GDLK ++ V+ P Sbjct: 672 DSKFKMPKFKMPLFGASAPGKSM-EASVDVSAPKV--EADVSLLSMQGDLKTTDLSVQTP 728 Query: 1619 KMDVNVGDIDIEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDMDVSVPKV 1678 D++++ + +K P+ +PE G +KG + PKV Sbjct: 729 S-----ADLEVQDGQVDVKLPEGPLPE------------------GASLKGHL----PKV 761 Query: 1679 EG-EMKVPDVDIKGPKVDIDAPDVEVHDPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLP 1737 + +K+P VD+KGPK+D+ P EV PD + + M EVDV P Sbjct: 762 QRPSLKMPKVDLKGPKLDLKGPKAEVTAPDVKMSLSSM---------------EVDVQAP 806 Query: 1738 KADIDVSGPSVDTDAPDLDIEGPEGKLKGSKFKMPKLNIKAPKVSMPDVDLNLKGPKLKG 1797 +A +D + D D ++ + K K KFKMP + AP SM D +++ PK+ Sbjct: 807 RAKLDGARLEGDLSLADKEVTAKDSKFKMPKFKMPSFGVSAPGKSMED-SVDVSAPKV-- 863 Query: 1798 EIDASVPELEGDLRGPQVDVKGPFVEAEVP--DVDLECPDA-------------KLKGPK 1842 E D S+ ++GDL+ + ++ P + EV VD++ P+ K++ P Sbjct: 864 EADVSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGPKVHLPKVEMPS 923 Query: 1843 FKMPEMHFKAPKISMPDVDLHLKGPKVK---GDADVSVPKLEGDLTGPSVGVE------- 1892 FKMP++ K P+I + L LKGPK + D +VS+P +E D+ ++ Sbjct: 924 FKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDGEVSLPSMEVDVQAQKAKLDGAWLEGD 983 Query: 1893 --VPDVELECPDAKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDVDVSVPKLEGD 1950 + D ++ D+K K PKFKMP AP G +K VDVS PK+E D Sbjct: 984 LSLADKDVTAKDSKFKMPKFKMPSFGVSAP------------GKSIKALVDVSAPKVEAD 1031 Query: 1951 LTGPSVG------------------VEVPDVELECPD------AKLKG-------PKFKM 1979 L+ PS+ V+ V+++ P+ A LKG P FKM Sbjct: 1032 LSLPSMQGDLKTTDLSIQPASTDLKVQADQVDVKLPEGHLPEGAGLKGHLPKVEMPSFKM 1091 Query: 1980 PEMHFKTPKISMPDVDLHLKGPKVK---GDMDVSVPKVEGEMKVPDVDIKGPKMD--IDA 2034 P++ K P++ + L LK PK + D++VS+P VE +++ P + +++ + Sbjct: 1092 PKVALKGPQVDVKGPKLDLKSPKAEVTAPDVEVSLPSVEVDVEAPGAKLDSARLEGELSL 1151 Query: 2035 PDVDVHGPDWHLKMPKMKMPKF--SMPGFKAEGPEVDVNLPKADVVVSGPKV--DVEVPD 2090 D DV D KMPK KMP F S PG E VDV+ PK + VS P + D++ D Sbjct: 1152 ADKDVTAKDSRFKMPKFKMPSFGASAPGKSIEA-SVDVSAPKVEADVSLPSMQGDLKTTD 1210 Query: 2091 VS-------------------LEG--PEG--------KLKGPKLKMPEMHFKAPKISMPD 2121 +S LEG PEG K++ P LKMP++ K P++ + Sbjct: 1211 LSIQPPSADLEVHAGQVDVKLLEGHVPEGAGFKGHLPKVQMPSLKMPKVDLKGPQVEVRG 1270 Query: 2122 VDLHLKGPKVK---GDVDVSLPKLEGDLTGPSV---------DVEVPDVELECPDAKLKG 2169 L LKG K + +V VSLP +E D+ P D+ + D ++ D+K K Sbjct: 1271 PKLDLKGHKAEVTAHEVAVSLPSVEVDMQAPGAKLDGAQLDGDLSLADKDVTAKDSKFKM 1330 Query: 2170 PKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMDVSVPKVEGEMKVPDVDIRGPKVDID- 2228 PKFKMP P S+ + +++L PKV+ DM S+P ++G++K D+ I+ P D++ Sbjct: 1331 PKFKMPSFGVSAPGKSI-EASVDLSAPKVEADM--SLPSMQGDLKTTDLSIQPPSTDLEL 1387 Query: 2229 -APDVDVHGPDWHLK--------MPKMKMPKFSMPGFKGEGPEVDVNLPKAD-----VDV 2274 A +DV P+ + +PK++MP F +P +GPE+D+ PK D V+V Sbjct: 1388 QAGQLDVKLPEGPVPEGAGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKLDLKDPKVEV 1447 Query: 2275 SGPKVDVEVP--DVSLEGPEGKLKGPKFK-----------MPEMHFKTPKISMPDVDFNL 2321 + P V+V +P +V +E P KL G + + + FK PK MP + Sbjct: 1448 TAPDVEVSLPSVEVDVEAPGAKLDGGRLEEDMSLADKDLTTKDSKFKMPKFKMPSFGVSA 1507 Query: 2322 KGPKIKGDVDVSAPKLE---------GELKGPELDVKGPKLDADMP--EVAVEGPNG--- 2367 G I+ VDVSAPK+E G+LK +L ++ P D ++ +V V+ P G Sbjct: 1508 PGKSIEASVDVSAPKVEADVSLPSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVS 1567 Query: 2368 ----------KWKTPKFKMPDMHFKAPKISMPDLDLHLKSPKAKG------------EVD 2405 K + P FKMP + K P+I + L LK PK + EVD Sbjct: 1568 EGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKVEVTAPDVKMSLSSMEVD 1627 Query: 2406 VDVPKLEGDLKGPHVDVSGPDIDIEGPEGKLKGPKFKMPDMHFKAPNISMPDVDLNLKGP 2465 V P+ + D D+S D + + K K PKFKMP AP S+ + +++ P Sbjct: 1628 VQAPRAKLDGAQLEGDLSLADKAVTAKDSKFKMPKFKMPSFGVSAPGKSI-EASVDVSEP 1686 Query: 2466 KIKGDVDVSVPEVEGKLEVPDMNIRGPKVDVNAP----DVQAPDWHLK--------MPKM 2513 K+ + DVS+P ++G L+ D++I+ P D+ +V+ P+ L +PK+ Sbjct: 1687 KV--EADVSLPSMQGDLKTTDLSIQSPSADLEVQAGQVNVKLPEGPLPEGAGFKGHLPKV 1744 Query: 2514 KMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDIEGPDV---------NIEGPEGKLKG 2564 +MP MP +GP++DV PK +D+ GPK ++ PDV ++E P KL Sbjct: 1745 QMPSLKMPKVALKGPQMDVKGPK--LDLKGPKAEVMAPDVEVSLPSVEVDVEAPGAKLDS 1802 Query: 2565 PKLK-----------MPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVE-------- 2605 +L+ + K PK MP F + G ++ VDVS PKVE Sbjct: 1803 VRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSAPKVEAEVSLPSM 1862 Query: 2606 -GDLKGPEVDIKGPKVD--INAPDVGVQGPDWHLK--------MPKVKMPKFSMPGFKGE 2654 GDLK ++ I P D + A V ++ P+ + +PKV MP F MP + Sbjct: 1863 QGDLKTTDLCIPLPSADLVVQAGQVDMKLPEGQVPEGAGLKGHLPKVDMPSFKMPKVDLK 1922 Query: 2655 GPDGDVKLPKADIDVSGPKVDIEGPDVNIEGP---------------------------- 2686 GP DVK A +D+ GPK ++ PDV + P Sbjct: 1923 GPQTDVK--GAKLDLKGPKAEVTAPDVEVSLPSMEVDVQAQKAKLDGARLEGDLSLADKD 1980 Query: 2687 ----EGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVD 2742 + K K PKFKMP + AP S+ + +++ PKV + DVSLP ++GDLK ++ Sbjct: 1981 MTAKDSKFKMPKFKMPSFGVSAPGRSI-EASVDVPAPKV--EADVSLPSMQGDLKTTDLS 2037 Query: 2743 IKGPKVD--IDAPDVDVHGPDWHLK--------MPKIKMPKISMPGFKGEGPDVDVNLPK 2792 I+ P D + VDV P+ H+ +PK++MP + MP +GP VD+ PK Sbjct: 2038 IQPPSADLKVQTGQVDVKLPEGHVPEGAGLKGHLPKVEMPSLKMPKVDLKGPQVDIKGPK 2097 Query: 2793 ADIDVSGPKVDVECPDVNIEGP--EGKWKSPKFKMPEMH------------------FKT 2832 +D+ PKV++ PDV + P E ++P+ K+ H FK Sbjct: 2098 --LDLKDPKVEMRVPDVEVSLPSMEVDVQAPRAKLDSAHLQGDLTLANKDLTTKDSKFKM 2155 Query: 2833 PKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPEV--DLKGPKVDIDV--PDVNVQGP 2888 PK MP ++ G I+ VDV+ PKVE D+ P + DLK + I DV VQ Sbjct: 2156 PKFKMPSFGVSAPGKSIEASVDVSPPKVEADMSLPSMQGDLKTTDLSIQPLSADVKVQAG 2215 Query: 2889 DWHLKM---------------PKMKMPKFSMPGFKAEGPEVDVNLPKAD-----VDVSGP 2928 +K+ PK++MP F +P +GPE+D+ PK D V+V+ P Sbjct: 2216 QVDVKLLEGPVPEEVGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKLDLKDPKVEVTAP 2275 Query: 2929 KVDVEGP--DVNIEGPEGKLKGPKFK-----------MPEMNIKAPKIPMPDFDLHLKGP 2975 V+V P +V+++ P KL G + + + K PK M F + G Sbjct: 2276 DVEVSLPSVEVDVKAPGAKLDGARLEGDMSLADKDVTAKDSKFKMPKFKMLSFGVSALGK 2335 Query: 2976 KV---------KGDVDISLPKVEGDLKGPEVDIRGP---------QVDIDVPDVGV-QGP 3016 + K + D+SLP ++GDLK ++ ++ P QVD+ +P+ V +G Sbjct: 2336 SIEASADVSALKVEADVSLPSMQGDLKTTDLSVQPPSADLEVQAGQVDVKLPEGPVPEGA 2395 Query: 3017 DWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDV---------NI 3067 +PK++MP F MP +GP +DV PK LD+ GPK D+ PDV ++ Sbjct: 2396 GLKGHLPKLQMPSFKMPKVDLKGPQIDVKGPK--LDLKGPKTDVMAPDVEVSQPSVEVDV 2453 Query: 3068 EGPEGKLKGPKFK-----------MPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKV 3116 E P KL G + + K PK MP ++ G ++ +DVS PKV Sbjct: 2454 EAPGAKLDGAWLEGDLSVADKDVTTKDSRFKIPKFKMPSFGVSAPGKSIEASVDVSAPKV 2513 Query: 3117 E---------GDMKVPDVDIKGPKVD--INAPDVDVQGPDWHLK--------MPKIKMPK 3157 E GD+K D+ I+ P D + A VDV+ P+ + +PK++MP Sbjct: 2514 EADGSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGLKGHLPKVQMPS 2573 Query: 3158 ISMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDV---------NIEGPDAKLKG---- 3204 MP +GP++DV PK LD+ GPK +V PDV +++ P AKL G Sbjct: 2574 FKMPEMDLKGPQLDVKGPK--LDLKGPKAEVTAPDVEMSLSSMEVDVQAPRAKLDGARLE 2631 Query: 3205 -------------------PKFKMPEMNIKAPKISMPDLDLNLKGPKMKGEVDVSLANVE 3245 PKFKMP + AP S+ L + ++K E D+SL +++ Sbjct: 2632 GDLSLADKGVTAKDSKFKMPKFKMPSFRVSAPGESIEAL---VDVSELKVEADMSLPSMQ 2688 Query: 3246 GDLKGPALDIKGP--KIDVDAPDIDIHGPDAKL-KGPKLKMPDMHVNMPKISMPEIDLNL 3302 GDLK + I+ P +++V A +D+ P+ + +G LK + MP MPE+DL Sbjct: 2689 GDLKTTDISIQPPSAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKLQMPSFKMPEVDLKG 2748 Query: 3303 KGSKLKG-DVDVSGPKLEGDIKAPSLDIKGPEVDVSGPKLNIEGK--------------S 3347 +KG +VD+ GPK E + + EVDV P+ ++G + Sbjct: 2749 PQIDVKGPNVDLKGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGMTA 2808 Query: 3348 KKSRFKLPKFNFSGSKVQTP------EVDVKGKKPDIDITGPKV--DINAPDVEVQG--- 3396 K S+FK+PKF V P VDV K + D + P + D+ D+ +Q Sbjct: 2809 KDSKFKMPKFKMPSFGVSAPGKSIEASVDVSELKVEADGSFPSMQGDLKTTDIRIQPPSA 2868 Query: 3397 -----------------------------KVKGSKFKMPFLSISSPKVSMPDVELNLKSP 3427 KV+ FKMP + + P++ + +L+LK P Sbjct: 2869 QLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGP 2928 Query: 3428 KVK---GDLDIAGPNLEGDFKGP--KVDIKAPEVNLNAPDVDVHGPDWNLKMPKMKMPKF 3482 K + D++++ P++E D + P K+D E +L+ D DV D KMPK KMP F Sbjct: 2929 KAEVTAPDVEVSLPSVEVDVEAPRAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSF 2988 Query: 3483 SVSG---------------LKAEG--PDVAVDLPKGDINIEGPS--MNIEGPDLNVEGPE 3523 VS ++AE P + DL DI+IE PS + ++ ++++ PE Sbjct: 2989 GVSAPGKSIEVSVDVSAPKVEAEVSLPSMQGDLKTTDISIEPPSAQLEVQAGQVDLKLPE 3048 Query: 3524 G------GLKG-------PKFKMPDMNIKAPKISMPDIDLNLKGPKVK---GDVDISLPK 3567 G GLKG P FKMP ++ K P+I + L+LKGPK DV++S P Sbjct: 3049 GHVPEGAGLKGHLPKLQMPSFKMPKVDRKGPQIDVKGPKLDLKGPKTDVTAPDVEVSQPG 3108 Query: 3568 LEGDLKGPEVDIKGPKV--DINAPDVDVHGPDWHLKMPKVKMPKF--SMPGFKGEGPEVD 3623 +E D++ P + G ++ D++ D DV D KMPK KMP F S PG K VD Sbjct: 3109 MEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPG-KSIEVLVD 3167 Query: 3624 VTLPKADIDISGPNVDVDVP--DVNIEGPDA----------------------------- 3652 V+ PK + D+S P++ D+ D++IE P A Sbjct: 3168 VSAPKVEADLSLPSMQGDLKNTDISIEPPSAQLEVQAGQVDVKLPEGHVLEGAGLKGHLP 3227 Query: 3653 KLKGPKFKMPEMNIKAPKISMPDFDLNLKGPKMK---GDVVVSLPKVEGDLKGPEVDIKG 3709 KL+ P FKMP+++ K P+I + L+LKGPKM DV VS P +E D++ P + G Sbjct: 3228 KLQMPSFKMPKVDRKGPQIDIKGPKLDLKGPKMDVTAPDVEVSQPSMEVDVEAPGAKLDG 3287 Query: 3710 PKV--DIDTPDINIEGSEGKFKGPKFKIPEMHLKAPKISMPDIDLNLKGPKVKGDVDVSL 3767 ++ D+ D ++ + KFK PKFK+P AP S+ +++ PK + DVSL Sbjct: 3288 ARLEGDLSLADKDVTAKDSKFKMPKFKMPSYRASAPGKSI-QASVDVSAPKA--EADVSL 3344 Query: 3768 PKMEGDLKGPEVDIKGPKVD--INAPDVDVQGPDWHLK--------MPKVKMPKFSMPGF 3817 P M+GDLK ++ I+ P VD + A VDV+ P+ H+ +PKV+MP F MP Sbjct: 3345 PSMQGDLKTTDLSIQLPSVDLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVEMPSFKMPKV 3404 Query: 3818 KGEGPDVDVNLPKADLDVSGPKVDIDVPDV---------NIEGPEGKLKG---------- 3858 + P VD+ PK DL V PK ++ VPDV +++ P KL G Sbjct: 3405 DLKSPQVDIKGPKLDLKV--PKAEVTVPDVEVSLPSVEVDVQAPRAKLDGARLEGDLSLA 3462 Query: 3859 -------------PKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMQVP 3905 PKFKMP + AP S+ + L++ PKV+ D VSL ++GD++ Sbjct: 3463 EKDVTAKDSKFKMPKFKMPSFGVSAPGRSI-EASLDVSAPKVEAD--VSLSSMQGDLKAT 3519 Query: 3906 DLDIKGPKVD--INAPDVDVR--------GPDWHLKMPKIKMPKISMPGFKGEGPEVDVN 3955 DL I+ P D + A VDV G +PK++MP + P +GP++DV Sbjct: 3520 DLSIQPPSADLEVQAVQVDVELLEGPVPEGAGLKGHLPKVEMPSLKTPKVDLKGPQIDVK 3579 Query: 3956 LPKADLDVSGPKVDVDVPDVNIEGP--------------------------------DAK 3983 PK LD+ GPK +V VPDV + P D+K Sbjct: 3580 GPK--LDLKGPKAEVRVPDVEVSLPSVEVDVQAPKAKLDAGRLEGDLSLADKDVTAKDSK 3637 Query: 3984 LKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKVD 4043 K PKFKMP + AP SM + + + PKV + DVSLP M+GDLK ++ I+ P D Sbjct: 3638 FKMPKFKMPSFRVSAPGKSM-EASVDVSAPKV--EADVSLPSMQGDLKTTDLSIQPPSAD 3694 Query: 4044 --IDAPDVDVHGPDWHLK--------MPKVKMPKFSMPGFKGEGPEVDVNLPKADIDVS- 4092 + A +DV P+ + +PKV+MP MP +GP+VD+ PK D+ VS Sbjct: 3695 LKVQAGQMDVKLPEGQVPEGAGLKEHLPKVEMPSLKMPKVDLKGPQVDIKGPKLDLKVSK 3754 Query: 4093 ----GPKVDIDTP--DIDIHGPEGKL-----------------------KGPKFKMPDLH 4123 P V++ P ++D+ P KL K PKFKMP Sbjct: 3755 AEVTAPDVEVSLPSVEVDVQAPRAKLDSAQLEGDLSLADKDVTAKDSKFKMPKFKMPSFG 3814 Query: 4124 LKAPKISMPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDVP--DVDVQG 4181 + AP S+ E +++ PK+ + DVSLP ++GDLK ++ I+ D+ V VD++ Sbjct: 3815 VSAPGKSI-EASVHVSAPKV--EADVSLPSMQGDLKTTDLSIQPHSADLTVQARQVDMKL 3871 Query: 4182 PDWHLK--------MPKVKMPKFSMPGFKGEGPDVDVNLPKADL-----DVSGPKVDIDV 4228 + H+ +PKV+MP F MP +GP++D+ PK DL +V+ P V++ + Sbjct: 3872 LEGHVPEEAGLKGHLPKVQMPSFKMPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSL 3931 Query: 4229 P--DVNIEGPDAKLKG-----------------------PKFKMPEMNIKAPKISMPDFD 4263 P +V++E P AKL G PKFKMP + AP SM + Sbjct: 3932 PSVEVDVEAPGAKLDGARLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGKSM-EAS 3990 Query: 4264 LHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDID--APDVDVHGPDWHLK------ 4315 + + PKV + DVSLP ++GDLK ++ ++ P D++ A VDV P+ + Sbjct: 3991 VDVTAPKV--EADVSLPSMQGDLKATDLSVQPPSADLEVQAGQVDVKLPEGPVPEGASLK 4048 Query: 4316 --MPKVKMPKFSMPGFKGEGPDVDVTLPKADIEISGPKVDIDAP---------DVSIEGP 4364 +PKV+MP F MP +GP +DV PK D++ GPK ++ AP +V ++ P Sbjct: 4049 GHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLK--GPKAEVTAPDVKMSLSSMEVDVQAP 4106 Query: 4365 -----------------------DAKLKGPKFKMPEMNIKAP-----------------K 4384 D+K K PKFKMP + AP Sbjct: 4107 RAKLDGVQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSMEASVDVSELKAKAD 4166 Query: 4385 ISMPDI-------DFNLKGPKVK-----GDVDVSLPK----------------------- 4409 +S+P + D +++ P G VDV LP+ Sbjct: 4167 VSLPSMQGDLKTTDLSIQSPSADLEVQAGQVDVKLPEGPLPKGAGLKGHLPKVQMPCLKM 4226 Query: 4410 -------VEGDLKGPEIDIKGPSLDIDTP---------DVNIEGPEGKL----------- 4442 + D+KGP++D+KGP D+ TP +V++E P KL Sbjct: 4227 PKVALKGPQVDVKGPKLDLKGPKADVMTPVVEVSLPSMEVDVEAPGAKLDSVRLEGDLSL 4286 Query: 4443 ------------KGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVESDLKG 4490 K PKFKMP + AP S+ + L +K + DVSLP ++ DLK Sbjct: 4287 ADKDMTAKDSKFKMPKFKMPSFGVSAPGKSI---EASLDVSALKVEADVSLPSMQGDLKT 4343 Query: 4491 PEV----------------DIEGPEG-------------KLKGPKFKMPDVHFKSPQISM 4521 + D++ PEG KL+ P FK+P V K PQI + Sbjct: 4344 THLSIQPPSADLEVQAGQEDVKLPEGPVHEGAGLKGHLPKLQMPSFKVPKVDLKGPQIDV 4403 Query: 4522 SDIDLNLKGPKIK---GDMDISVPKLEGDLKGP--KVDVKGPKVGIDTPDIDIHGPEGKL 4576 + L+LKGPK++ ++D+S+P +E D++ P K+D + + D D+ + K Sbjct: 4404 NVPKLDLKGPKVEVTSPNLDVSLPSMEVDIQAPGAKLDSTRLEGDLSLADKDVTAKDSKF 4463 Query: 4577 KGPKFKMPDLHLKAPKISMPEVDLNLKGPKVKGDMDISLPKVEGDLKGPEVDIRDPKVDI 4636 K PKFKMP + +P S+ EV +++ PK++ DM S+P ++GDLK ++ I+ P D+ Sbjct: 4464 KMPKFKMPSFGMLSPGKSI-EVSVDVSAPKMEADM--SIPSMQGDLKTTDLRIQAPSADL 4520 Query: 4637 DVP--DVDVQGPDWHLK--------MPKVKMPKFSMPGFKGEGPDVDVNLPKADIDVSGP 4686 +V VD++ P+ H+ +PKV+MP F MP +GP VDV PK +D+ GP Sbjct: 4521 EVQAGQVDLKLPEGHMPEVAGLKGHLPKVEMPSFKMPKVDLKGPQVDVKGPK--LDLKGP 4578 Query: 4687 KVDVDVPDVNIE--------------------------------GPDAKLKGPKFKMPEM 4714 K +V PDV + G D+K +GPK Sbjct: 4579 KAEVMAPDVEVSLPSVETDVQAPGSMLDGARLEGDLSLAHEDVAGKDSKFQGPKLSTSGF 4638 Query: 4715 SIKAPKISMPDIDL-----------------------NLKGPKVKGDVDVTLPKVEGDLK 4751 + K+SM ++ +L P G++ + + +V D K Sbjct: 4639 EWSSKKVSMSSSEIEGNVTFHEKTSTFPIVESVVHEGDLHDPSRDGNLGLAVGEVGMDSK 4698 Query: 4752 GPEADIKGPKVDIN---TP-DVDVHGPDWHLKM-----------------------PKVK 4784 + K PKV + TP D V G + + P ++ Sbjct: 4699 FKKLHFKVPKVSFSSTKTPKDSLVPGAKSSIGLSTIPLSSSECSSFELQQVSACSEPSMQ 4758 Query: 4785 MPKFSMPGFKGEGPDVDVSLPKADIDVSGPKVDVDIPDVNIEGPDAKLKGPKFKMPEINI 4844 MPK GF +D++ P + + P DV + + P A L PE+ + Sbjct: 4759 MPKVGFAGFPSSR--LDLTGPHFESSILSPCEDVTLTKYQVTVPRAALA------PELAL 4810 Query: 4845 KAPKISIPDVDLDLKGPKVKGDFDVSVPKVEGTLKGPEVDLKGPRLDFEGPDA--KLSGP 4902 + P S D+ L PK + D+ P EG GP L+ P + ++S P Sbjct: 4811 EIPSGSQADIPL----PKTECSTDLQPP--EGVPTSQAESHSGP-LNSMIPVSLGQVSFP 4863 Query: 4903 SLKMPSLEISAPKVTAPDVDLHLKAPKIGFSGPKLEGGEVDLKGPKVEAPS--------- 4953 P S P++ P+ DLH A P G V P + PS Sbjct: 4864 KFYKPKFVFSVPQMAVPEGDLHA-AVGAPVMSPLSPGERVQCPLPSTQLPSPGTCVSQGP 4922 Query: 4954 ------LDVHMDSP--------DINIEGPDVKIPKFKKPKFGFGAKS-------PKADIK 4992 L + +P D +G +K+PK K P F + K P+ ++ Sbjct: 4923 EELVASLQTSVVAPGEAPSEDADHEGKGSPLKMPKIKLPSFRWSPKKETGPKVDPECSVE 4982 Query: 4993 SPSL------DVTVPEAELNLETPEISVGGKGKKSK--FKMPKIHMSGPKIKAKKQGFDL 5044 L D P++ ++++ P G KG+ +K F MPK+ + PK+KA K G L Sbjct: 4983 DSKLSLVLDKDEVAPQSAIHMDLPPERDGEKGRSTKPGFAMPKLAL--PKMKASKSGVSL 5040 Query: 5045 NVPGGEIDASLKAPDV-----DVNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEFDIKS 5099 P ++D SL + D A D + + ++ P V I S Sbjct: 5041 --PQRDVDPSLSSATAGGSFQDTEKASSDGGRGGLGATASATGSEGVNLHRPQVH--IPS 5096 Query: 5100 PKFKAEAPLPSPKLEGELQAPDLELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGDL 5159 F A+ L S K + E+ P+ +L LP L + + + DV +S P EG Sbjct: 5097 LGF-AKPDLRSSKAKVEVSQPEADLPLPK---HDLSTEGDSRGCGLGDVPVSQPCGEGIA 5152 Query: 5160 KGPK--VQANLGAPD---INIEGLDAKVKTP---SFGISAPQVSIPDVNVNLKGPKIKGD 5211 P+ +Q + PD + +E + + T P+ +P + + + G Sbjct: 5153 PTPEDPLQPSCRKPDAEVLTVESPEEEAMTKYSQESWFKMPKFRMPSLRRSFRDRGGAGK 5212 Query: 5212 VPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDV 5271 + + P G EA K +F + G +E A + QLP + ++ + Sbjct: 5213 LEVAQTQAPAAT--GGEAAAKVKEFL-----VSGSNVE---AAMSLQLPEADAEVTASES 5262 Query: 5272 KLEGP----DVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAP 5327 K D+ G + L + ++ ++S ++ ++ PS KG L +P M++ Sbjct: 5263 KSSTDILRCDLDSTGLKLHLSTAGMTGDELSTSEVRIH---PS-KGPLPFQMPGMRLPET 5318 Query: 5328 GLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSV 5387 + L G + + G + ++ T+ P+ L+ + D+ ++SV Sbjct: 5319 QV-LPGEIDETPLSKPGHDLASMEDKTEKWSSQPEGPLKLKASSTDMP-------SQISV 5370 Query: 5388 GAPDLSLEASEGSIKLPKMKLPQFGISTPGSD 5419 D E S ++K PK+ +P+F P S+ Sbjct: 5371 VNVDQLWEDSVLTVKFPKLMVPRFSFPAPSSE 5402 Score = 1583 bits (4100), Expect = 0.0 Identities = 1456/5128 (28%), Positives = 2251/5128 (43%), Gaps = 1288/5128 (25%) Query: 1723 PGFKAEGPEVDVNLPKADIDVSGPSV-DTDAPDLDIEGPEGKLKGSKFKMPKLNIKAPKV 1781 PG EG L +I ++ S+ DT I PE +++ K PK K Sbjct: 444 PGMSREGE--GEGLQSLEIGIARLSLRDTTEGGTQIGPPEIRVRVHDLKTPKFAFSTEKE 501 Query: 1782 SMPDVDLNLKGPKLKGEIDASVPELEGDLRGPQVDVKG------PFVEAEVP-------- 1827 P+ + L P+ DAS G L+G +V+ G P AE Sbjct: 502 --PERERRLSTPQRGKRQDASSKAGTG-LKGEEVEGAGWMPGREPTTHAEAQGDEGDGEE 558 Query: 1828 -----------DVDLECPDAKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDADVS 1876 D E + +++ PKFK+P + + K H K + K D Sbjct: 559 GLQRTRITEEQDKGREDTEGQIRMPKFKIPSLGWSPSK--------HTKTGREKATEDTE 610 Query: 1877 VPKLEGDLTGPSVGVE-------------------------------------VPDVELE 1899 + EG+ T + E + + E+ Sbjct: 611 QGR-EGEATATADRREQRRTEEGLKDKEDSDSMTNTTKIQLIHDEKRLKKEQILTEKEVA 669 Query: 1900 CPDAKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDVDVSVPKLEGDLTGPSVGVE 1959 D+K K PKFKMP AP SM + + + PKV + DVS+ ++GDL + V+ Sbjct: 670 TKDSKFKMPKFKMPLFGASAPGKSM-EASVDVSAPKV--EADVSLLSMQGDLKTTDLSVQ 726 Query: 1960 VPDVELECPD---------------AKLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVK 2004 P +LE D A LKG K+ K PK+ + L LKGPK + Sbjct: 727 TPSADLEVQDGQVDVKLPEGPLPEGASLKGHLPKVQRPSLKMPKVDLKGPKLDLKGPKAE 786 Query: 2005 ---GDMDVSVPKVEGEMKVPDVDIKGPKM--DIDAPDVDVHGPDWHLKMPKMKMPKF--S 2057 D+ +S+ +E +++ P + G ++ D+ D +V D KMPK KMP F S Sbjct: 787 VTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKEVTAKDSKFKMPKFKMPSFGVS 846 Query: 2058 MPGFKAEGPEVDVNLPK--ADVVVSGPKVDVEVPDVSLEGPEGKLK-------------- 2101 PG K+ VDV+ PK ADV +S + D++ D+S++ P L+ Sbjct: 847 APG-KSMEDSVDVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGP 905 Query: 2102 -----GPKLKMPEMH---FKAPKISM--PDVD-----LHLKGPKVK---GDVDVSLPKLE 2143 GPK+ +P++ FK PK+ + P +D L LKGPK + D +VSLP +E Sbjct: 906 VPEGAGPKVHLPKVEMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDGEVSLPSME 965 Query: 2144 GDLTGPSV---------DVEVPDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVNLNLK 2194 D+ D+ + D ++ D+K K PKFKMP P S+ + +++ Sbjct: 966 VDVQAQKAKLDGAWLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIKAL-VDVS 1024 Query: 2195 GPKVKGDMDVSVPKVEGEMKVPDVDIRGPKVD--IDAPDVDVHGPDWHLK--------MP 2244 PKV+ D+ S+P ++G++K D+ I+ D + A VDV P+ HL +P Sbjct: 1025 APKVEADL--SLPSMQGDLKTTDLSIQPASTDLKVQADQVDVKLPEGHLPEGAGLKGHLP 1082 Query: 2245 KMKMPKFSMPGFKGEGPEVDVNLPKADV-----DVSGPKVDVEVP--DVSLEGPEGKLKG 2297 K++MP F MP +GP+VDV PK D+ +V+ P V+V +P +V +E P KL Sbjct: 1083 KVEMPSFKMPKVALKGPQVDVKGPKLDLKSPKAEVTAPDVEVSLPSVEVDVEAPGAKLDS 1142 Query: 2298 PKFK-----------MPEMHFKTPKISMPDVDFNLKGPKIKGDVDVSAPKLE-------- 2338 + + + FK PK MP + G I+ VDVSAPK+E Sbjct: 1143 ARLEGELSLADKDVTAKDSRFKMPKFKMPSFGASAPGKSIEASVDVSAPKVEADVSLPSM 1202 Query: 2339 -GELKGPELDVKGPKLDADM--------------PEVA-VEGPNGKWKTPKFKMPDMHFK 2382 G+LK +L ++ P D ++ PE A +G K + P KMP + K Sbjct: 1203 QGDLKTTDLSIQPPSADLEVHAGQVDVKLLEGHVPEGAGFKGHLPKVQMPSLKMPKVDLK 1262 Query: 2383 APKISMPDLDLHLKSPKAK---GEVDVDVPKLEGDLKGPHV---------DVSGPDIDIE 2430 P++ + L LK KA+ EV V +P +E D++ P D+S D D+ Sbjct: 1263 GPQVEVRGPKLDLKGHKAEVTAHEVAVSLPSVEVDMQAPGAKLDGAQLDGDLSLADKDVT 1322 Query: 2431 GPEGKLKGPKFKMPDMHFKAPNISMPDVDLNLKGPKIKGDVDVSVPEVEGKLEVPDMNIR 2490 + K K PKFKMP AP S+ + ++L PK+ + D+S+P ++G L+ D++I+ Sbjct: 1323 AKDSKFKMPKFKMPSFGVSAPGKSI-EASVDLSAPKV--EADMSLPSMQGDLKTTDLSIQ 1379 Query: 2491 GPKVDVNAP----DVQAPDWHLK--------MPKMKMPKFSMPGFKAEGPEVDVNLPKAD 2538 P D+ DV+ P+ + +PK++MP F +P +GPE+D+ PK Sbjct: 1380 PPSTDLELQAGQLDVKLPEGPVPEGAGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPK-- 1437 Query: 2539 VDISGPKVDIEGPDV---------NIEGPEGKLKGPKLK-----------MPEMNIKAPK 2578 +D+ PKV++ PDV ++E P KL G +L+ + K PK Sbjct: 1438 LDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGGRLEEDMSLADKDLTTKDSKFKMPK 1497 Query: 2579 ISMPDFDLHLKGPKVKGDVDVSLPKVE---------GDLKGPEVDIKGPKVD--INAPDV 2627 MP F + G ++ VDVS PKVE GDLK ++ I+ P D + A V Sbjct: 1498 FKMPSFGVSAPGKSIEASVDVSAPKVEADVSLPSMQGDLKATDLSIQPPSADLEVQAGQV 1557 Query: 2628 GVQGPDWHLK--------MPKVKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPKVDIEGP 2679 V+ P+ + +PKV+MP F MP +GP DVK PK +D+ GPKV++ P Sbjct: 1558 DVKLPEGPVSEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPK--LDLKGPKVEVTAP 1615 Query: 2680 DV---------NIEGPEGKLKG-----------------------PKFKMPEMNIKAPKI 2707 DV +++ P KL G PKFKMP + AP Sbjct: 1616 DVKMSLSSMEVDVQAPRAKLDGAQLEGDLSLADKAVTAKDSKFKMPKFKMPSFGVSAPGK 1675 Query: 2708 SMPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDID--APDVDVHGPDWHLK 2765 S+ + +++ PKV + DVSLP ++GDLK ++ I+ P D++ A V+V P+ L Sbjct: 1676 SI-EASVDVSEPKV--EADVSLPSMQGDLKTTDLSIQSPSADLEVQAGQVNVKLPEGPLP 1732 Query: 2766 --------MPKIKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDV-------- 2809 +PK++MP + MP +GP +DV PK +D+ GPK +V PDV Sbjct: 1733 EGAGFKGHLPKVQMPSLKMPKVALKGPQMDVKGPK--LDLKGPKAEVMAPDVEVSLPSVE 1790 Query: 2810 -NIEGPEGKWKSPKFK-----------MPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTG 2857 ++E P K S + + + FK PK MP ++ G I+ VDV+ Sbjct: 1791 VDVEAPGAKLDSVRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSA 1850 Query: 2858 PKVE---------GDLKG-------PEVDL--KGPKVDIDVPDVNV-QGPDWHLKMPKMK 2898 PKVE GDLK P DL + +VD+ +P+ V +G +PK+ Sbjct: 1851 PKVEAEVSLPSMQGDLKTTDLCIPLPSADLVVQAGQVDMKLPEGQVPEGAGLKGHLPKVD 1910 Query: 2899 MPKFSMPGFKAEGPEVDVNLPKADVDVSGPKVDVEGPDVNIEGP---------------- 2942 MP F MP +GP+ DV A +D+ GPK +V PDV + P Sbjct: 1911 MPSFKMPKVDLKGPQTDVK--GAKLDLKGPKAEVTAPDVEVSLPSMEVDVQAQKAKLDGA 1968 Query: 2943 ----------------EGKLKGPKFKMPEMNIKAPKIPMPDFDLHLKGPKVKGDVDISLP 2986 + K K PKFKMP + AP + + + + PKV+ DV SLP Sbjct: 1969 RLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGRSI-EASVDVPAPKVEADV--SLP 2025 Query: 2987 KVEGDLKGPEVDIRGPQVDIDVP--DVGVQGPDWHLK--------MPKVKMPKFSMPGFK 3036 ++GDLK ++ I+ P D+ V V V+ P+ H+ +PKV+MP MP Sbjct: 2026 SMQGDLKTTDLSIQPPSADLKVQTGQVDVKLPEGHVPEGAGLKGHLPKVEMPSLKMPKVD 2085 Query: 3037 GEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGP-------------------------- 3070 +GP VD+ PK LD+ PKV++ VPDV + P Sbjct: 2086 LKGPQVDIKGPK--LDLKDPKVEMRVPDVEVSLPSMEVDVQAPRAKLDSAHLQGDLTLAN 2143 Query: 3071 ------EGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMKVPD 3124 + K K PKFKMP + AP S+ + +++ PKV+ DM SLP ++GD+K D Sbjct: 2144 KDLTTKDSKFKMPKFKMPSFGVSAPGKSI-EASVDVSPPKVEADM--SLPSMQGDLKTTD 2200 Query: 3125 VDIKGPKVDIN--APDVDV---QGP---DWHLK--MPKIKMPKISMPGFKGEGPEVDVNL 3174 + I+ D+ A VDV +GP + LK +PK++MP +P +GPE+D+ Sbjct: 2201 LSIQPLSADVKVQAGQVDVKLLEGPVPEEVGLKGHLPKLQMPSFKVPKVDLKGPEIDIKG 2260 Query: 3175 PKADL-----DVSGPKVDVDVP--DVNIEGPDAKLKGP------------------KFKM 3209 PK DL +V+ P V+V +P +V+++ P AKL G KFKM Sbjct: 2261 PKLDLKDPKVEVTAPDVEVSLPSVEVDVKAPGAKLDGARLEGDMSLADKDVTAKDSKFKM 2320 Query: 3210 PEMNIKAPKISM--PDLDLNLKGPKMKGEVDVSLANVEGDLKGPALDIKGPKID--VDAP 3265 P+ + + +S ++ + +K E DVSL +++GDLK L ++ P D V A Sbjct: 2321 PKFKMLSFGVSALGKSIEASADVSALKVEADVSLPSMQGDLKTTDLSVQPPSADLEVQAG 2380 Query: 3266 DIDIHGPD------AKLKG--PKLKMPDMHVNMPKISMPEIDLNLKGSKLKGDVDVSGPK 3317 +D+ P+ A LKG PKL+MP MPK+ + +++KG KL D+ GPK Sbjct: 2381 QVDVKLPEGPVPEGAGLKGHLPKLQMPSF--KMPKVDLKGPQIDVKGPKL----DLKGPK 2434 Query: 3318 LEGDIKAPSLDIKGP--EVDVSGPKLNIEGK--------------SKKSRFKLPKFNFSG 3361 D+ AP +++ P EVDV P ++G +K SRFK+PKF Sbjct: 2435 T--DVMAPDVEVSQPSVEVDVEAPGAKLDGAWLEGDLSVADKDVTTKDSRFKIPKFKMPS 2492 Query: 3362 SKVQTPEVDVKGKKPDIDITGPKVDINAPDVEVQGKVKGSKF------------------ 3403 V P ++ +D++ PKV+ + +QG +K + Sbjct: 2493 FGVSAPGKSIEAS---VDVSAPKVEADGSLSSMQGDLKATDLSIQPPSADLEVQAGQVDV 2549 Query: 3404 KMPFLSISS--------PKVSMPDV---ELNLKSPKVKGDLDIAGPNLEGDFKGPKVDIK 3452 K+P + PKV MP E++LK P+ LD+ GP L D KGPK ++ Sbjct: 2550 KLPEGPVPEGAGLKGHLPKVQMPSFKMPEMDLKGPQ----LDVKGPKL--DLKGPKAEVT 2603 Query: 3453 APEV--NLNAPDVDVHGP-----------------------DWNLKMPKMKMPKFSVSG- 3486 AP+V +L++ +VDV P D KMPK KMP F VS Sbjct: 2604 APDVEMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGVTAKDSKFKMPKFKMPSFRVSAP 2663 Query: 3487 ------------LKAEG----PDVAVDLPKGDINIEGPS--MNIEGPDLNVEGPEG---- 3524 LK E P + DL DI+I+ PS + ++ ++V+ PEG Sbjct: 2664 GESIEALVDVSELKVEADMSLPSMQGDLKTTDISIQPPSAQLEVQAGQVDVKLPEGHVPE 2723 Query: 3525 --GLKG-------PKFKMPDMNIKAPKISMPDIDLNLKGPKVK---GDVDISLPKLEGDL 3572 GLKG P FKMP++++K P+I + +++LKGPK + DV +SL +E D+ Sbjct: 2724 GAGLKGHLPKLQMPSFKMPEVDLKGPQIDVKGPNVDLKGPKAEVTAPDVKMSLSSMEVDV 2783 Query: 3573 KGPEVDIKGPKV--DINAPDVDVHGPDWHLKMPKVKMPKF-------------------- 3610 + P + G ++ D++ D + D KMPK KMP F Sbjct: 2784 QAPRAKLDGARLEGDLSLADKGMTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSELKV 2843 Query: 3611 ----SMPGFKGEGPEVDVTL--PKADIDISGPNVDVDVPD------VNIEGPDAKLKGPK 3658 S P +G+ D+ + P A +++ VDV +P+ ++G K++ P Sbjct: 2844 EADGSFPSMQGDLKTTDIRIQPPSAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVQMPS 2903 Query: 3659 FKMPEMNIKAPKISMPDFDLNLKGPKMK---GDVVVSLPKVEGDLKGPEVDIKGPKV--D 3713 FKMP++++K P+I + L+LKGPK + DV VSLP VE D++ P + G ++ D Sbjct: 2904 FKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDVEVSLPSVEVDVEAPRAKLDGARLEGD 2963 Query: 3714 IDTPDINIEGSEGKFKGPKFKIPEMHLKAPKISMPDIDLNLKGPKVKGDVDVSLPKMEGD 3773 + D ++ + KFK PKFK+P + AP S+ ++ +++ PKV + +VSLP M+GD Sbjct: 2964 LSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSI-EVSVDVSAPKV--EAEVSLPSMQGD 3020 Query: 3774 LKGPEVDIKGP--KVDINAPDVDVQGPDWHLK--------MPKVKMPKFSMPGFKGEGPD 3823 LK ++ I+ P ++++ A VD++ P+ H+ +PK++MP F MP +GP Sbjct: 3021 LKTTDISIEPPSAQLEVQAGQVDLKLPEGHVPEGAGLKGHLPKLQMPSFKMPKVDRKGPQ 3080 Query: 3824 VDVNLPKADLDVSGPKVDIDVPDVNIEGP------------------------------- 3852 +DV PK LD+ GPK D+ PDV + P Sbjct: 3081 IDVKGPK--LDLKGPKTDVTAPDVEVSQPGMEVDVEAPGAKLDGARLEGDLSLADKDVTA 3138 Query: 3853 -EGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMQVPDLDIKG 3911 + K K PKFKMP + AP S+ ++ +++ PKV+ D+ SLP ++GD++ D+ I+ Sbjct: 3139 KDSKFKMPKFKMPSFGVSAPGKSI-EVLVDVSAPKVEADL--SLPSMQGDLKNTDISIEP 3195 Query: 3912 P--KVDINAPDVDVRGPDWHL--------KMPKIKMPKISMPGFKGEGPEVDVNLPKADL 3961 P ++++ A VDV+ P+ H+ +PK++MP MP +GP++D+ PK L Sbjct: 3196 PSAQLEVQAGQVDVKLPEGHVLEGAGLKGHLPKLQMPSFKMPKVDRKGPQIDIKGPK--L 3253 Query: 3962 DVSGPKVDVDVPDV---------NIEGPDAKLKGPKFK-----------MPEMNIKAPKI 4001 D+ GPK+DV PDV ++E P AKL G + + + K PK Sbjct: 3254 DLKGPKMDVTAPDVEVSQPSMEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKMPKF 3313 Query: 4002 SMPDFDLHLKGPKV---------KGDVDVSLPKMEGDLKAPEVDIKGPKVDID--APDVD 4050 MP + G + K + DVSLP M+GDLK ++ I+ P VD++ A VD Sbjct: 3314 KMPSYRASAPGKSIQASVDVSAPKAEADVSLPSMQGDLKTTDLSIQLPSVDLEVQAGQVD 3373 Query: 4051 VHGPDWHLK--------MPKVKMPKFSMPGFKGEGPEVDVNLPKADIDVSGPKVDIDTPD 4102 V P+ H+ +PKV+MP F MP + P+VD+ PK D+ V PK ++ PD Sbjct: 3374 VKLPEGHVPEGAGLKGHLPKVEMPSFKMPKVDLKSPQVDIKGPKLDLKV--PKAEVTVPD 3431 Query: 4103 I---------DIHGPEGKLKG-----------------------PKFKMPDLHLKAPKIS 4130 + D+ P KL G PKFKMP + AP S Sbjct: 3432 VEVSLPSVEVDVQAPRAKLDGARLEGDLSLAEKDVTAKDSKFKMPKFKMPSFGVSAPGRS 3491 Query: 4131 MPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDVPDVDV----------Q 4180 + E L++ PK+ + DVSL ++GDLK ++ I+ P D++V V V + Sbjct: 3492 I-EASLDVSAPKV--EADVSLSSMQGDLKATDLSIQPPSADLEVQAVQVDVELLEGPVPE 3548 Query: 4181 GPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGP---- 4236 G +PKV+MP P +GP +DV PK LD+ GPK ++ VPDV + P Sbjct: 3549 GAGLKGHLPKVEMPSLKTPKVDLKGPQIDVKGPK--LDLKGPKAEVRVPDVEVSLPSVEV 3606 Query: 4237 ----------------------------DAKLKGPKFKMPEMNIKAPKISMPDFDLHLKG 4268 D+K K PKFKMP + AP SM + + + Sbjct: 3607 DVQAPKAKLDAGRLEGDLSLADKDVTAKDSKFKMPKFKMPSFRVSAPGKSM-EASVDVSA 3665 Query: 4269 PKVKGDVDVSLPKVEGDLKGPEVDIKGPKVD--IDAPDVDVHGPDWHLK--------MPK 4318 PKV + DVSLP ++GDLK ++ I+ P D + A +DV P+ + +PK Sbjct: 3666 PKV--EADVSLPSMQGDLKTTDLSIQPPSADLKVQAGQMDVKLPEGQVPEGAGLKEHLPK 3723 Query: 4319 VKMPKFSMPGFKGEGPDVDVTLPKADI-----EISGPKVDIDAP--DVSIEGP------- 4364 V+MP MP +GP VD+ PK D+ E++ P V++ P +V ++ P Sbjct: 3724 VEMPSLKMPKVDLKGPQVDIKGPKLDLKVSKAEVTAPDVEVSLPSVEVDVQAPRAKLDSA 3783 Query: 4365 ----------------DAKLKGPKFKMPEMNIKAPKISMPDIDFNLKGPKVKGDVDVSLP 4408 D+K K PKFKMP + AP S+ + ++ PKV + DVSLP Sbjct: 3784 QLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSI-EASVHVSAPKV--EADVSLP 3840 Query: 4409 KVEGDLKGPEIDIKGPSLDIDTP---------------DVNIEGPEGKLKGPKFKMPEMN 4453 ++GDLK ++ I+ S D+ + ++G K++ P FKMP+++ Sbjct: 3841 SMQGDLKTTDLSIQPHSADLTVQARQVDMKLLEGHVPEEAGLKGHLPKVQMPSFKMPKVD 3900 Query: 4454 IKAPKISMPDFDLHLKGPKVK---GDVDVSLPKVESDLKGPEVDIEGP------------ 4498 +K P+I + L LK PKV+ DV+VSLP VE D++ P ++G Sbjct: 3901 LKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGARLEGDLSLADKD 3960 Query: 4499 ----EGKLKGPKFKMPDVHFKSPQISMSDIDLNLKGPKIKGDMDISVPKLEGDLKGPKVD 4554 + K K PKFKMP +P SM + +++ PK++ D +S+P ++GDLK + Sbjct: 3961 MTAKDSKFKMPKFKMPSFGVSAPGKSM-EASVDVTAPKVEAD--VSLPSMQGDLKATDLS 4017 Query: 4555 VKGPKVGIDTP--DIDIHGPEG-------------KLKGPKFKMPDLHLKAPKISMPEVD 4599 V+ P ++ +D+ PEG K++ P FKMP + LK P+I + Sbjct: 4018 VQPPSADLEVQAGQVDVKLPEGPVPEGASLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPK 4077 Query: 4600 LNLKGPKVKGDMDISLPKVEGDLKGPEVDIRDPKV---------DIDVPDVDVQGPDWHL 4650 L+LKGPK +++ P V+ L EVD++ P+ D+ + D DV D Sbjct: 4078 LDLKGPKA----EVTAPDVKMSLSSMEVDVQAPRAKLDGVQLEGDLSLADKDVTAKDSKF 4133 Query: 4651 KMPKVKMPKF------------------------SMPGFKGE--GPDVDVNLPKADIDVS 4684 KMPK KMP F S+P +G+ D+ + P AD++V Sbjct: 4134 KMPKFKMPSFGVSAPGKSMEASVDVSELKAKADVSLPSMQGDLKTTDLSIQSPSADLEVQ 4193 Query: 4685 GPKVDVDVPD------VNIEGPDAKLKGPKFKMPEMSIKAPKISMPDIDLNLKGPK---V 4735 +VDV +P+ ++G K++ P KMP++++K P++ + L+LKGPK + Sbjct: 4194 AGQVDVKLPEGPLPKGAGLKGHLPKVQMPCLKMPKVALKGPQVDVKGPKLDLKGPKADVM 4253 Query: 4736 KGDVDVTLPKVEGDLKGPEADIKGPKV--DINTPDVDVHGPDWHLKMPKVKMPKF----- 4788 V+V+LP +E D++ P A + ++ D++ D D+ D KMPK KMP F Sbjct: 4254 TPVVEVSLPSMEVDVEAPGAKLDSVRLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAP 4313 Query: 4789 -------------------SMPGFKGEGPDVDVSL--PKADIDVSGPKVDVDIPD----- 4822 S+P +G+ +S+ P AD++V + DV +P+ Sbjct: 4314 GKSIEASLDVSALKVEADVSLPSMQGDLKTTHLSIQPPSADLEVQAGQEDVKLPEGPVHE 4373 Query: 4823 -VNIEGPDAKLKGPKFKMPEINIKAPKISIPDVDLDLKGPKVK---GDFDVSVPKVEGTL 4878 ++G KL+ P FK+P++++K P+I + LDLKGPKV+ + DVS+P +E + Sbjct: 4374 GAGLKGHLPKLQMPSFKVPKVDLKGPQIDVNVPKLDLKGPKVEVTSPNLDVSLPSMEVDI 4433 Query: 4879 KGPEVDLKGPRL---------DFEGPDAKLSGPSLKMPS-------------LEISAPKV 4916 + P L RL D D+K P KMPS +++SAPK+ Sbjct: 4434 QAPGAKLDSTRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGMLSPGKSIEVSVDVSAPKM 4493 Query: 4917 TA----PDVDLHLKAPKIGFSGP----KLEGGEVDLKGPKVEAPSL--------DVHMDS 4960 A P + LK + P +++ G+VDLK P+ P + V M S Sbjct: 4494 EADMSIPSMQGDLKTTDLRIQAPSADLEVQAGQVDLKLPEGHMPEVAGLKGHLPKVEMPS 4553 Query: 4961 ---PDINIEGPDVKIPKFKKPKFGFGAKSPKADIKSPSLDVTVPEAELNLETPEISVGGK 5017 P ++++GP V + K PK K PKA++ +P ++V++P E +++ P + G Sbjct: 4554 FKMPKVDLKGPQVDV---KGPKLDL--KGPKAEVMAPDVEVSLPSVETDVQAPGSMLDGA 4608 Query: 5018 --------------GKKSKFKMPKIHMSGPKIKAKKQGFDLNVPGGEI------------ 5051 GK SKF+ PK+ SG + +KK + G + Sbjct: 4609 RLEGDLSLAHEDVAGKDSKFQGPKLSTSGFEWSSKKVSMSSSEIEGNVTFHEKTSTFPIV 4668 Query: 5052 -----DASLKAPDVDVNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEFDIKSPKFKAEA 5106 + L P D N+ + +D K F K++F + S K ++ Sbjct: 4669 ESVVHEGDLHDPSRDGNLGLAVGEVGMDSK--------FKKLHFKVPKVSFSSTKTPKDS 4720 Query: 5107 PLPSPKLEGELQAPDLELSLPAIHVEGLDIKAKAPKVKMPDVDIS-VPKIEGDLKGPKVQ 5165 +P K L L S + P ++MP V + P DL GP + Sbjct: 4721 LVPGAKSSIGLSTIPLSSSECSSFELQQVSACSEPSMQMPKVGFAGFPSSRLDLTGPHFE 4780 Query: 5166 ANLGAPDINIEGLDAKVKTPSFGI---------SAPQVSIP----DVNVNLKGPKIKGDV 5212 +++ +P ++ +V P + S Q IP + + +L+ P+ V Sbjct: 4781 SSILSPCEDVTLTKYQVTVPRAALAPELALEIPSGSQADIPLPKTECSTDLQPPE---GV 4837 Query: 5213 PSVGLEGPDVDLQG----PEAKIKFPKFSMPK------------------IGIPGVKMEG 5250 P+ E L ++ FPKF PK +G P + Sbjct: 4838 PTSQAESHSGPLNSMIPVSLGQVSFPKFYKPKFVFSVPQMAVPEGDLHAAVGAPVMSPLS 4897 Query: 5251 GGAEVHAQLPSLE--------------------------GDLRGPDVKLEGPDVSLKGPG 5284 G V LPS + G+ D EG LK P Sbjct: 4898 PGERVQCPLPSTQLPSPGTCVSQGPEELVASLQTSVVAPGEAPSEDADHEGKGSPLKMPK 4957 Query: 5285 VDLPSVNLSMPKVSGPDLD----LNLKGPSLKGDLDASVPSMKVH--------------- 5325 + LPS S K +GP +D + SL D D P +H Sbjct: 4958 IKLPSFRWSPKKETGPKVDPECSVEDSKLSLVLDKDEVAPQSAIHMDLPPERDGEKGRST 5017 Query: 5326 APGLNLSGVG-GKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPK 5384 PG + + KM+ GV +P D L+ G S Q S D + Sbjct: 5018 KPGFAMPKLALPKMKASKSGVSLPQRDVDPSLSSAT-----AGGSFQDTEKASSD--GGR 5070 Query: 5385 VSVGAPDLSLEASEG-SIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLK 5443 +GA S SEG ++ P++ +P G + P + + + E+ P D+ L Sbjct: 5071 GGLGA-TASATGSEGVNLHRPQVHIPSLGFAKP------DLRSSKAKVEVSQPEADLPL- 5122 Query: 5444 GPRISAPNVDFNLEGPKVKGSLG------ATGEIKGPTVGGGL------PGIGVQGLEG- 5490 P D + EG LG GE PT L P V +E Sbjct: 5123 ------PKHDLSTEGDSRGCGLGDVPVSQPCGEGIAPTPEDPLQPSCRKPDAEVLTVESP 5176 Query: 5491 -----------------NLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVG 5533 +MP ++ S D G KL Q P GG Sbjct: 5177 EEEAMTKYSQESWFKMPKFRMPSLRRSFRDRGGAG---KLEVAQTQAPAATGG------- 5226 Query: 5534 FHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDI------SLG-EG 5586 + + K F ++ + ++L+ P+ S S+ DI S G + Sbjct: 5227 ------EAAAKVKEFLVSGSNVEAAMSLQLPEADAEVTASESKSSTDILRCDLDSTGLKL 5280 Query: 5587 HLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKV---EGGVKGGQIG---LQAPGL 5640 HLS G G+ +S + + SK G L F P + E V G+I L PG Sbjct: 5281 HLSTAGMTGD---ELSTSEVRIHPSK--GPLPFQMPGMRLPETQVLPGEIDETPLSKPGH 5335 Query: 5641 SVSGPQGHLESGSGKVTFPKMKIPKFTFSGRELVGREMGVDVHFPKAEASIQAGAGDGEW 5700 ++ + E S + P K S ++ + V+V D W Sbjct: 5336 DLASMEDKTEKWSSQPEGPL----KLKASSTDMPSQISVVNV--------------DQLW 5377 Query: 5701 EESEVKLKKSKIKMPKFNFSKPKGKGGV 5728 E+S + +K K+ +P+F+F P + V Sbjct: 5378 EDSVLTVKFPKLMVPRFSFPAPSSEDDV 5405 Score = 1581 bits (4093), Expect = 0.0 Identities = 1542/5755 (26%), Positives = 2496/5755 (43%), Gaps = 1429/5755 (24%) Query: 2 EKEETTRELLLPNWQGSGSHGLTIAQR-DDGVFVQEVTQNSPAARTGVVKEGDQIVGATI 60 E + E+ L +G+ G ++ D G+FV++V ++S AA+ ++EGDQ++ T+ Sbjct: 105 EAVQEATEVTLKTEVEAGASGYSVTGGGDQGIFVKQVLKDSSAAKLFNLREGDQLLSTTV 164 Query: 61 YFDNLQSGEVTQLLNTMGHHTVGLKLHRKGDRSPEPGQTWTREVFSSCSSEVVLSGDDEE 120 +F+N++ + ++L + V K+ R+ P P E ++S ++ G ++E Sbjct: 165 FFENIKYEDALKILQYSEPYKVQFKIRRQ---LPAPQD----EEWASSDAQHGPQGKEKE 217 Query: 121 YQRIYTTKIKPRLKSEDGVEGDLGETQSRTITVTRRVTAYTVDVTGREGAKDIDISSPEF 180 + + K+ +G +GD Q R I+ R GR+ ++ +S P+F Sbjct: 218 DTDVADGCRETPTKTLEG-DGD----QERLISKPRVGR-------GRQSQRE-RLSWPKF 264 Query: 181 KIKIPRHELTEISNVDVETQSGKTVIRLPSGSGAASPTGSAVDIRAGAISASGPELQGAG 240 + ++++ G R S S A P D + +++ E Q Sbjct: 265 Q--------------SIKSKRGPGPQRSHSSSEAYEPR----DAHDVSPTSTDTEAQLTV 306 Query: 241 HSKLQVTMPGIKVGGSGVNVNAKGLDLGGRGGVQVPAVDISSSLGGRAV-EVQGPSLESG 299 + Q PG + +N+ + G P S +G V E GP +S Sbjct: 307 ERQEQKAGPGSQRRRKFLNLRFRTGSGQGPSSTGQPGRGFQSGVGRAGVLEELGPWGDS- 365 Query: 300 DHGKIKFPTMKVPKFGVSTG--REGQTPKAGLRVSAPEVSVGHKGGKPGLTIQAPQLEVS 357 + + G +TG RE + + + A + + + G P L PQ Sbjct: 366 -----------LEETGAATGSRREERAEQDREVMPAQSMPLPTELGDPRLCEGTPQ---- 410 Query: 358 VPSANIEGLEGKLKGPQITGPSLEG---DLGLKGAKPQGHIGVDASAPQIGGSITGPSVE 414 EG L+ ++ G +LEG + + KP+ P G S G Sbjct: 411 ---------EGGLRAARLHGKTLEGQAQETAVAQRKPRAQ-------PTPGMSREGEGEG 454 Query: 415 VQAPDIDVQG---------------PGSKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGE 459 +Q+ +I + P ++ V +K PKF+ S K E ++ P Sbjct: 455 LQSLEIGIARLSLRDTTEGGTQIGPPEIRVRVHDLKTPKFAFSTEKEPERERRLSTPQR- 513 Query: 460 VTVPGVSGDVSLPEIATGGLEGKMKGTKVKTPEMIIQKPKISMQDVDLSLGSPKLKGDIK 519 G D S + TG +KG +V+ G+ + G Sbjct: 514 ----GKRQDAS-SKAGTG-----LKGEEVE--------------------GAGWMPGREP 543 Query: 520 VSAPGVQGDVKGPQVALKGSRVDIETP----NLEGTLTGPRLGSPS-------------- 561 + QGD + L+ +R+ E + EG + P+ PS Sbjct: 544 TTHAEAQGDEGDGEEGLQRTRITEEQDKGREDTEGQIRMPKFKIPSLGWSPSKHTKTGRE 603 Query: 562 --------GKTGTCRISMSEVDLNVAAPKVKGGVDVTLPRVEGKVKVPEVDVRGPKVDVS 613 G+ G + + +K D K+++ + R K + Sbjct: 604 KATEDTEQGREGEATATADRREQRRTEEGLKDKEDSDSMTNTTKIQLIHDEKRLKKEQIL 663 Query: 614 APDVEAHGPEWNLKMPKMKMPTFSTPGAKGEGPDVHMTLPKGDISISGPKVNVEAPDVNL 673 + E + KMPK KMP F GA G + + + +S PKV + +++ Sbjct: 664 T-EKEVATKDSKFKMPKFKMPLF---GASAPGKSM-----EASVDVSAPKVEADVSLLSM 714 Query: 674 EGLGGKLKGPDVKLPDMSVKTPKISMPDVDLHVKGTKVKGEYDVTVPKLEGELKGPKVDI 733 +G D+K D+SV+TP DL V+ G+ DV +P EG L Sbjct: 715 QG--------DLKTTDLSVQTPS-----ADLEVQD----GQVDVKLP--EGPLP------ 749 Query: 734 DAPDVDVHGPDWHLKMPKMKMPKFSVPGFKAEGPEVDVNLPKADVDISGPKIDVTAPDVS 793 G +PK++ P +P +GP++D+ PKA+V K+ +++ +V Sbjct: 750 -------EGASLKGHLPKVQRPSLKMPKVDLKGPKLDLKGPKAEVTAPDVKMSLSSMEVD 802 Query: 794 IEEPEGKLKGPKFK-----------MPEMNIKVPKISMPDVDLHLKGPNVKGEYDVTMPK 842 ++ P KL G + + + K+PK MP + G +++ DV+ PK Sbjct: 803 VQAPRAKLDGARLEGDLSLADKEVTAKDSKFKMPKFKMPSFGVSAPGKSMEDSVDVSAPK 862 Query: 843 VESEIKV------------------PDVELKSAKMDIDVPD---VEVQGPDWHLKMPKMK 881 VE+++ + D+E+++ ++D+ +P+ E GP HL PK++ Sbjct: 863 VEADVSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGPKVHL--PKVE 920 Query: 882 MPKFSMPGFKAEGPEVDVNLPKADVDISGPKVGVEVPD---------VNIEGPEGKLKG- 931 MP F MP +GP++DV PK +D+ GPK V PD V+++ + KL G Sbjct: 921 MPSFKMPKVDLKGPQIDVKGPK--LDLKGPKAEVTAPDGEVSLPSMEVDVQAQKAKLDGA 978 Query: 932 ----------------------PKFKMPEMNIKAPKISMPDVDLHMKGPKVKGEYDMTVP 969 PKFKMP + AP S+ + + + PKV E D+++P Sbjct: 979 WLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIKAL-VDVSAPKV--EADLSLP 1035 Query: 970 KLEGDLK----------------GPKVDVSAPDVEM-QGPDWNLKMPKIKMPKFSMPSLK 1012 ++GDLK +VDV P+ + +G +PK++MP F MP + Sbjct: 1036 SMQGDLKTTDLSIQPASTDLKVQADQVDVKLPEGHLPEGAGLKGHLPKVEMPSFKMPKVA 1095 Query: 1013 GEGPEFDVNLSKANVDISAPKVDTNAPD---------LSLEGPEGKLKGPKFK------- 1056 +GP+ DV K +D+ +PK + APD + +E P KL + + Sbjct: 1096 LKGPQVDVKGPK--LDLKSPKAEVTAPDVEVSLPSVEVDVEAPGAKLDSARLEGELSLAD 1153 Query: 1057 ----MPEMHFRAPKMSLPDVDLDLKGPKMKGNVDISAPKIEGEMQVP------------- 1099 + F+ PK +P G ++ +VD+SAPK+E ++ +P Sbjct: 1154 KDVTAKDSRFKMPKFKMPSFGASAPGKSIEASVDVSAPKVEADVSLPSMQGDLKTTDLSI 1213 Query: 1100 -----DVDIRGPKVDIKAPDVEG---QGLDWSLKIPKMKMPKFSMPSLKGEGPEVDVNLP 1151 D+++ +VD+K +EG +G + +PK++MP MP + +GP+V+V P Sbjct: 1214 QPPSADLEVHAGQVDVKL--LEGHVPEGAGFKGHLPKVQMPSLKMPKVDLKGPQVEVRGP 1271 Query: 1152 KAD------------VVVSGP--KVDIEAPDVSLEG----------------PEGKLKGP 1181 K D V VS P +VD++AP L+G + K K P Sbjct: 1272 KLDLKGHKAEVTAHEVAVSLPSVEVDMQAPGAKLDGAQLDGDLSLADKDVTAKDSKFKMP 1331 Query: 1182 KFKMPEMHFKTPKISMPDVDLHLKGPKVKGDVDVSVPKVEGEMKVPDVEIKGPKMDID-- 1239 KFKMP P S+ + + L PKV + D+S+P ++G++K D+ I+ P D++ Sbjct: 1332 KFKMPSFGVSAPGKSI-EASVDLSAPKV--EADMSLPSMQGDLKTTDLSIQPPSTDLELQ 1388 Query: 1240 APDVEVQGPDWHL--------KMPKMKMPKFSMPGFKGEGREVDVNLPKAD-----IDVS 1286 A ++V+ P+ + +PK++MP F +P +G E+D+ PK D ++V+ Sbjct: 1389 AGQLDVKLPEGPVPEGAGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKLDLKDPKVEVT 1448 Query: 1287 GPKVDVEVP--DVSLEGPEGKLKG-----------------------PKFKMPEMHFKAP 1321 P V+V +P +V +E P KL G PKFKMP AP Sbjct: 1449 APDVEVSLPSVEVDVEAPGAKLDGGRLEEDMSLADKDLTTKDSKFKMPKFKMPSFGVSAP 1508 Query: 1322 KISMPDVDLNLKGPKLKGDVDVSLPEVEGEMKVPDVDIKGPKVD--ISAPDVDVHGPDWH 1379 S+ + +++ PK+ + DVSLP ++G++K D+ I+ P D + A VDV P+ Sbjct: 1509 GKSI-EASVDVSAPKV--EADVSLPSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGP 1565 Query: 1380 LK--------MPKVKMPKFSMPGFKGEGPEVDVKLPKADVDVSGPKMDAEVPD------- 1424 + +PKV+MP F MP +GP++DVK PK +D+ GPK++ PD Sbjct: 1566 VSEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPK--LDLKGPKVEVTAPDVKMSLSS 1623 Query: 1425 --VNIEGPDAKLKG-----------------------PKFKMPEMSIKPQKISIPDVGLH 1459 V+++ P AKL G PKFKMP + SI + + Sbjct: 1624 MEVDVQAPRAKLDGAQLEGDLSLADKAVTAKDSKFKMPKFKMPSFGVSAPGKSI-EASVD 1682 Query: 1460 LKGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKVD--INAPDVEVHGPDWHL--------K 1509 + PK++ DV++P ++G++K D+ I+ P D + A V V P+ L Sbjct: 1683 VSEPKVEA--DVSLPSMQGDLKTTDLSIQSPSADLEVQAGQVNVKLPEGPLPEGAGFKGH 1740 Query: 1510 MPKVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPD---------VNLEAPEG 1560 +PKV+MP MP +GP++D+ PK DL GPK ++ PD V++EAP Sbjct: 1741 LPKVQMPSLKMPKVALKGPQMDVKGPKLDL--KGPKAEVMAPDVEVSLPSVEVDVEAPGA 1798 Query: 1561 KL------------------KGPKFKMPSMNIQTHKISMP----DVGLNLKAPKLKTDVD 1598 KL K KFKMP + + +S P + +++ APK+ + + Sbjct: 1799 KLDSVRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSAPKV--EAE 1856 Query: 1599 VSLPKVEGDLKGPEIDVKAPKMD--VNVGDIDIEGPEGK------LKG-------PKFKM 1643 VSLP ++GDLK ++ + P D V G +D++ PEG+ LKG P FKM Sbjct: 1857 VSLPSMQGDLKTTDLCIPLPSADLVVQAGQVDMKLPEGQVPEGAGLKGHLPKVDMPSFKM 1916 Query: 1644 PEMHFKAPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKVDIDAP---- 1699 P++ K P+ + L LKGPK +V+ P VE + +VD++ K +D Sbjct: 1917 PKVDLKGPQTDVKGAKLDLKGPKA----EVTAPDVEVSLPSMEVDVQAQKAKLDGARLEG 1972 Query: 1700 DVEVHDPDWHLKMPKMKMPKFSMPGFKAEGP------EVDVNLPKADIDVSGPSVDTD-- 1751 D+ + D D K K KMPKF MP F P VDV PK + DVS PS+ D Sbjct: 1973 DLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGRSIEASVDVPAPKVEADVSLPSMQGDLK 2032 Query: 1752 ----------------APDLDIEGPEG-------------KLKGSKFKMPKLNIKAPKVS 1782 +D++ PEG K++ KMPK+++K P+V Sbjct: 2033 TTDLSIQPPSADLKVQTGQVDVKLPEGHVPEGAGLKGHLPKVEMPSLKMPKVDLKGPQVD 2092 Query: 1783 MPDVDLNLKGPKLK---GEIDASVPELEGDLRGPQVDVKGPFVEAE--VPDVDLECPDAK 1837 + L+LK PK++ +++ S+P +E D++ P+ + ++ + + + DL D+K Sbjct: 2093 IKGPKLDLKDPKVEMRVPDVEVSLPSMEVDVQAPRAKLDSAHLQGDLTLANKDLTTKDSK 2152 Query: 1838 LKGPKFKMPEMHFKAP--------KISMPDVDLHLKGPKVKGD---ADVSVPKLEGDLTG 1886 K PKFKMP AP +S P V+ + P ++GD D+S+ L D+ Sbjct: 2153 FKMPKFKMPSFGVSAPGKSIEASVDVSPPKVEADMSLPSMQGDLKTTDLSIQPLSADVKV 2212 Query: 1887 PSVGVEVPDVELECPD--------AKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVK- 1937 + V+V +E P+ KL+ P FK+P + K P+I + L LK PKV+ Sbjct: 2213 QAGQVDVKLLEGPVPEEVGLKGHLPKLQMPSFKVPKVDLKGPEIDIKGPKLDLKDPKVEV 2272 Query: 1938 --GDVDVSVPKLEGDLTGPSVGVE----VPDVELECPDAKLKGPKFKMPEMHFKTPKISM 1991 DV+VS+P +E D+ P ++ D+ L D K KFKMP+ + +S Sbjct: 2273 TAPDVEVSLPSVEVDVKAPGAKLDGARLEGDMSLADKDVTAKDSKFKMPKFKMLSFGVSA 2332 Query: 1992 --PDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKMDID--APDVDVHGPDWHL- 2046 ++ +K + DVS+P ++G++K D+ ++ P D++ A VDV P+ + Sbjct: 2333 LGKSIEASADVSALKVEADVSLPSMQGDLKTTDLSVQPPSADLEVQAGQVDVKLPEGPVP 2392 Query: 2047 -------KMPKMKMPKFSMPGFKAEGPEVDVNLPKADVVVSGPKVDVEVPD--------- 2090 +PK++MP F MP +GP++DV PK D + GPK DV PD Sbjct: 2393 EGAGLKGHLPKLQMPSFKMPKVDLKGPQIDVKGPKLD--LKGPKTDVMAPDVEVSQPSVE 2450 Query: 2091 VSLEGPEGKLKGPKLK-----------MPEMHFKAPKISMPDVDLHLKGPKVKGDVDVSL 2139 V +E P KL G L+ + FK PK MP + G ++ VDVS Sbjct: 2451 VDVEAPGAKLDGAWLEGDLSVADKDVTTKDSRFKIPKFKMPSFGVSAPGKSIEASVDVSA 2510 Query: 2140 PKLEGD----------------LTGPSVDVEVP--DVELECPD------AKLKG------ 2169 PK+E D + PS D+EV V+++ P+ A LKG Sbjct: 2511 PKVEADGSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGLKGHLPKVQ 2570 Query: 2170 -PKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMDVSVPKVEGEMKVPDVDIRGPKV--- 2225 P FKMPEM K P++ + L+LKGPK +V+ P VE + +VD++ P+ Sbjct: 2571 MPSFKMPEMDLKGPQLDVKGPKLDLKGPKA----EVTAPDVEMSLSSMEVDVQAPRAKLD 2626 Query: 2226 ------DIDAPDVDVHGPDWHLKMPKMKMPKF------------------------SMPG 2255 D+ D V D KMPK KMP F S+P Sbjct: 2627 GARLEGDLSLADKGVTAKDSKFKMPKFKMPSFRVSAPGESIEALVDVSELKVEADMSLPS 2686 Query: 2256 FKGEGPEVDVNL--PKADVDVSGPKVDVEVPD------VSLEGPEGKLKGPKFKMPEMHF 2307 +G+ D+++ P A ++V +VDV++P+ L+G KL+ P FKMPE+ Sbjct: 2687 MQGDLKTTDISIQPPSAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKLQMPSFKMPEVDL 2746 Query: 2308 KTPKISMPDVDFNLKGPKIK---GDVDVSAPKLEGELKGPELDVKGPKLDAD--MPEVAV 2362 K P+I + + +LKGPK + DV +S +E +++ P + G +L+ D + + + Sbjct: 2747 KGPQIDVKGPNVDLKGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGM 2806 Query: 2363 EGPNGKWKTPKFKMPDMHFKAP-------------KI----SMPDL-------DLHLKSP 2398 + K+K PKFKMP AP K+ S P + D+ ++ P Sbjct: 2807 TAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSELKVEADGSFPSMQGDLKTTDIRIQPP 2866 Query: 2399 KAK-----GEVDVDVPK--------LEG---------------DLKGPHVDVSGPDIDIE 2430 A+ G+VDV +P+ L+G DLKGP +DV GP +D++ Sbjct: 2867 SAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLK 2926 Query: 2431 GP----------------------------------------------EGKLKGPKFKMP 2444 GP + K K PKFKMP Sbjct: 2927 GPKAEVTAPDVEVSLPSVEVDVEAPRAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMP 2986 Query: 2445 DMHFKAPNISMPDVDLNLKGPKIKGDVDVSVPEVEGKLEVPDMNIRGP----KVDVNAPD 2500 AP S+ +V +++ PK+ + +VS+P ++G L+ D++I P +V D Sbjct: 2987 SFGVSAPGKSI-EVSVDVSAPKV--EAEVSLPSMQGDLKTTDISIEPPSAQLEVQAGQVD 3043 Query: 2501 VQAPDWHL--------KMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDIEGPD 2552 ++ P+ H+ +PK++MP F MP +GP++DV PK +D+ GPK D+ PD Sbjct: 3044 LKLPEGHVPEGAGLKGHLPKLQMPSFKMPKVDRKGPQIDVKGPK--LDLKGPKTDVTAPD 3101 Query: 2553 ---------VNIEGPEGKLKGPKLK-----------MPEMNIKAPKISMPDFDLHLKGPK 2592 V++E P KL G +L+ + K PK MP F + G Sbjct: 3102 VEVSQPGMEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKS 3161 Query: 2593 VKGDVDVSLPKVE---------GDLKGPEVDIKGP--KVDINAPDVGVQGPDWHL----- 2636 ++ VDVS PKVE GDLK ++ I+ P ++++ A V V+ P+ H+ Sbjct: 3162 IEVLVDVSAPKVEADLSLPSMQGDLKNTDISIEPPSAQLEVQAGQVDVKLPEGHVLEGAG 3221 Query: 2637 ---KMPKVKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPKVDIEGPDVNIEGP------- 2686 +PK++MP F MP +GP D+K PK +D+ GPK+D+ PDV + P Sbjct: 3222 LKGHLPKLQMPSFKMPKVDRKGPQIDIKGPK--LDLKGPKMDVTAPDVEVSQPSMEVDVE 3279 Query: 2687 -------------------------EGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKV 2721 + K K PKFKMP AP S+ +++ P Sbjct: 3280 APGAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSYRASAPGKSI-QASVDVSAP-- 3336 Query: 2722 KGDVDVSLPKVEGDLKGPEVDIKGPKVDID--APDVDVHGPDWHL--------KMPKIKM 2771 K + DVSLP ++GDLK ++ I+ P VD++ A VDV P+ H+ +PK++M Sbjct: 3337 KAEADVSLPSMQGDLKTTDLSIQLPSVDLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVEM 3396 Query: 2772 PKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGP--EGKWKSPKFKM---- 2825 P MP + P VD+ PK D+ V PK +V PDV + P E ++P+ K+ Sbjct: 3397 PSFKMPKVDLKSPQVDIKGPKLDLKV--PKAEVTVPDVEVSLPSVEVDVQAPRAKLDGAR 3454 Query: 2826 --------------PEMHFKTPKISMPDIDLNLTGPKIKGDVDVTGPKVE---------G 2862 + FK PK MP ++ G I+ +DV+ PKVE G Sbjct: 3455 LEGDLSLAEKDVTAKDSKFKMPKFKMPSFGVSAPGRSIEASLDVSAPKVEADVSLSSMQG 3514 Query: 2863 DLKGPEVDLKGPKVDIDVPDVNV----------QGPDWHLKMPKMKMPKFSMPGFKAEGP 2912 DLK ++ ++ P D++V V V +G +PK++MP P +GP Sbjct: 3515 DLKATDLSIQPPSADLEVQAVQVDVELLEGPVPEGAGLKGHLPKVEMPSLKTPKVDLKGP 3574 Query: 2913 EVDVNLPKADVDVSGPKVDVEGPDVNIEGP------------------------------ 2942 ++DV PK +D+ GPK +V PDV + P Sbjct: 3575 QIDVKGPK--LDLKGPKAEVRVPDVEVSLPSVEVDVQAPKAKLDAGRLEGDLSLADKDVT 3632 Query: 2943 --EGKLKGPKFKMPEMNIKAPKIPMPDFDLHLKGPKVKGDVDISLPKVEGDLKGPEVDIR 3000 + K K PKFKMP + AP M + + + PKV + D+SLP ++GDLK ++ I+ Sbjct: 3633 AKDSKFKMPKFKMPSFRVSAPGKSM-EASVDVSAPKV--EADVSLPSMQGDLKTTDLSIQ 3689 Query: 3001 GP---------QVDIDVPDVGV-QGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKAD 3050 P Q+D+ +P+ V +G +PKV+MP MP +GP VD+ PK D Sbjct: 3690 PPSADLKVQAGQMDVKLPEGQVPEGAGLKEHLPKVEMPSLKMPKVDLKGPQVDIKGPKLD 3749 Query: 3051 L-----DVSGPKVDIDVP--DVNIEGPEGKL-----------------------KGPKFK 3080 L +V+ P V++ +P +V+++ P KL K PKFK Sbjct: 3750 LKVSKAEVTAPDVEVSLPSVEVDVQAPRAKLDSAQLEGDLSLADKDVTAKDSKFKMPKFK 3809 Query: 3081 MPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMKVPDVDIKGPKVD--INAPD 3138 MP + AP S+ + +++ PKV + DVSLP ++GD+K D+ I+ D + A Sbjct: 3810 MPSFGVSAPGKSI-EASVHVSAPKV--EADVSLPSMQGDLKTTDLSIQPHSADLTVQARQ 3866 Query: 3139 VDVQGPDWHL--------KMPKIKMPKISMPGFKGEGPEVDVNLPKADL-----DVSGPK 3185 VD++ + H+ +PK++MP MP +GPE+D+ PK DL +V+ P Sbjct: 3867 VDMKLLEGHVPEEAGLKGHLPKVQMPSFKMPKVDLKGPEIDIKGPKLDLKDPKVEVTAPD 3926 Query: 3186 VDVDVP--DVNIEGPDAKLKG-----------------------PKFKMPEMNIKAPKIS 3220 V+V +P +V++E P AKL G PKFKMP + AP S Sbjct: 3927 VEVSLPSVEVDVEAPGAKLDGARLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGKS 3986 Query: 3221 MPDLDLNLKGPKMKGEVDVSLANVEGDLKGPALDIKGPKID--VDAPDIDIHGPDAKL-K 3277 M + +++ PK+ E DVSL +++GDLK L ++ P D V A +D+ P+ + + Sbjct: 3987 M-EASVDVTAPKV--EADVSLPSMQGDLKATDLSVQPPSADLEVQAGQVDVKLPEGPVPE 4043 Query: 3278 GPKLKMPDMHVNMPKISMPEIDLNLKGSKLKGDVDVSGPKLEGDIKAPSLDIKGPEVDVS 3337 G LK V MP MP++DL GP++ D+K P LD+KGP+ +V+ Sbjct: 4044 GASLKGHLPKVQMPSFKMPKVDL-------------KGPQI--DVKGPKLDLKGPKAEVT 4088 Query: 3338 GPKLNIEGKSKKSRFKLPKFNFSGSKVQTPEVDVKGKKPDIDITGPKVDINAPDVEVQGK 3397 P + + S + VQ P + G + + D++ D+ A D K Sbjct: 4089 APDVKMSLSSME------------VDVQAPRAKLDGVQLEGDLSLADKDVTAKD----SK 4132 Query: 3398 VKGSKFKMPFLSISSPKVSMPDVELNLKSPKVKGDLDIAGPNLEGDFKGPKVDIKAPEVN 3457 K KFKMP +S+P SM E ++ ++K D++ P+++GD K + I++P + Sbjct: 4133 FKMPKFKMPSFGVSAPGKSM---EASVDVSELKAKADVSLPSMQGDLKTTDLSIQSPSAD 4189 Query: 3458 L--NAPDVDVHGPDWNL-------------KMPKMKMPKFSVSG---------LKAEGPD 3493 L A VDV P+ L +MP +KMPK ++ G L +GP Sbjct: 4190 LEVQAGQVDVKLPEGPLPKGAGLKGHLPKVQMPCLKMPKVALKGPQVDVKGPKLDLKGPK 4249 Query: 3494 -------VAVDLPKGDINIEGP-----SMNIEG----PDLNVEGPEGGLKGPKFKMPDMN 3537 V V LP ++++E P S+ +EG D ++ + K PKFKMP Sbjct: 4250 ADVMTPVVEVSLPSMEVDVEAPGAKLDSVRLEGDLSLADKDMTAKDSKFKMPKFKMPSFG 4309 Query: 3538 IKAPKISMPDIDLNLKGPKVKGDVDISLPKLEGDLKGPEVDIKGPKV---------DINA 3588 + AP S I+ +L +K + D+SLP ++GDLK + I+ P D+ Sbjct: 4310 VSAPGKS---IEASLDVSALKVEADVSLPSMQGDLKTTHLSIQPPSADLEVQAGQEDVKL 4366 Query: 3589 PDVDVH-GPDWHLKMPKVKMPKFSMPGFKGEGPEVDVTLPKAD-----IDISGPNVDVDV 3642 P+ VH G +PK++MP F +P +GP++DV +PK D ++++ PN+DV + Sbjct: 4367 PEGPVHEGAGLKGHLPKLQMPSFKVPKVDLKGPQIDVNVPKLDLKGPKVEVTSPNLDVSL 4426 Query: 3643 P--DVNIEGP-----------------------DAKLKGPKFKMPEMNIKAPKISMPDFD 3677 P +V+I+ P D+K K PKFKMP + +P S+ + Sbjct: 4427 PSMEVDIQAPGAKLDSTRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGMLSPGKSI-EVS 4485 Query: 3678 LNLKGPKMKGDVVVSLPKVEGDLKGPEVDIKGPKVDIDT--------------PDI-NIE 3722 +++ PKM+ D +S+P ++GDLK ++ I+ P D++ P++ ++ Sbjct: 4486 VDVSAPKMEAD--MSIPSMQGDLKTTDLRIQAPSADLEVQAGQVDLKLPEGHMPEVAGLK 4543 Query: 3723 GSEGKFKGPKFKIPEMHLKAPKISMPDIDLNLKGPKVK---GDVDVSLPKMEGDLKGPEV 3779 G K + P FK+P++ LK P++ + L+LKGPK + DV+VSLP +E D++ P Sbjct: 4544 GHLPKVEMPSFKMPKVDLKGPQVDVKGPKLDLKGPKAEVMAPDVEVSLPSVETDVQAPGS 4603 Query: 3780 DIKGPKV--DINAPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSG 3837 + G ++ D++ DV G D K + PK S GF+ V ++ + + +V+ Sbjct: 4604 MLDGARLEGDLSLAHEDVAGKD-----SKFQGPKLSTSGFEWSSKKVSMSSSEIEGNVTF 4658 Query: 3838 PKVDIDVPDVNIEGPEGKLKGPK---------------FKMPEMNIKAPKISMPDIDLNL 3882 + P V EG L P K +++ K PK+S Sbjct: 4659 HEKTSTFPIVESVVHEGDLHDPSRDGNLGLAVGEVGMDSKFKKLHFKVPKVSFSSTKTPK 4718 Query: 3883 KG--PKVKGDMDVS-------------LPKV----EGDMQVPD----------LDIKGPK 3913 P K + +S L +V E MQ+P LD+ GP Sbjct: 4719 DSLVPGAKSSIGLSTIPLSSSECSSFELQQVSACSEPSMQMPKVGFAGFPSSRLDLTGPH 4778 Query: 3914 VD--INAPDVDVRGPDWHLKMPKIKM-PKISMPGFKGEGPEVDVNLPKAD--LDVSGPKV 3968 + I +P DV + + +P+ + P++++ G + D+ LPK + D+ P+ Sbjct: 4779 FESSILSPCEDVTLTKYQVTVPRAALAPELALE--IPSGSQADIPLPKTECSTDLQPPE- 4835 Query: 3969 DVDVPDVNIEGPDAKLKG-----------PKFKMPEMNIKAPKISMPDFDLH------LK 4011 VP E L PKF P+ P++++P+ DLH + Sbjct: 4836 --GVPTSQAESHSGPLNSMIPVSLGQVSFPKFYKPKFVFSVPQMAVPEGDLHAAVGAPVM 4893 Query: 4012 GPKVKGD-VDVSLPKMEGD------LKAPEVDIKGPKVDIDAP------DVDVHGPDWHL 4058 P G+ V LP + + PE + + + AP D D G L Sbjct: 4894 SPLSPGERVQCPLPSTQLPSPGTCVSQGPEELVASLQTSVVAPGEAPSEDADHEGKGSPL 4953 Query: 4059 KMPKVKMPKFSMPGFKGEGPEVDVNLPKADIDVSGPKVDID----TPDIDIH-------- 4106 KMPK+K+P F K GP+VD P+ ++ S + +D P IH Sbjct: 4954 KMPKIKLPSFRWSPKKETGPKVD---PECSVEDSKLSLVLDKDEVAPQSAIHMDLPPERD 5010 Query: 4107 GPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPE-VDI 4165 G +G+ P F MP L L K S V L P+ D +S G + E Sbjct: 5011 GEKGRSTKPGFAMPKLALPKMKASKSGVSL----PQRDVDPSLSSATAGGSFQDTEKASS 5066 Query: 4166 KGPKVDIDVPDVDVQGPDWHLKMPKVKMPK--FSMPGFKGEGPDVDVNLPKADLDVSGPK 4223 G + + +L P+V +P F+ P D+ KA ++VS P+ Sbjct: 5067 DGGRGGLGATASATGSEGVNLHRPQVHIPSLGFAKP---------DLRSSKAKVEVSQPE 5117 Query: 4224 VDIDVP--DVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPK 4281 D+ +P D++ EG D++ G GDV VS P Sbjct: 5118 ADLPLPKHDLSTEG-DSRGCG-----------------------------LGDVPVSQPC 5147 Query: 4282 VEGDLKGPEVDIKGPKVDIDAPDVDVHGPD-----WHLKMPKVKMPKFSMPGFKGEGPDV 4336 EG PE ++ DA + V P+ + + KMPKF MP + D Sbjct: 5148 GEGIAPTPEDPLQPSCRKPDAEVLTVESPEEEAMTKYSQESWFKMPKFRMPSLRRSFRDR 5207 Query: 4337 DVTLPKADIEISGPKVDIDAPDVSIEGPDAKLKGPKFKMPEMNIKAP-KISMPDIDFNLK 4395 +E++ AP + G +A K +F + N++A + +P+ D + Sbjct: 5208 G---GAGKLEVA----QTQAP--AATGGEAAAKVKEFLVSGSNVEAAMSLQLPEADAEVT 5258 Query: 4396 GPKVKGDVDVSLPKVEGDLKGPEIDIKGPSL---DIDTPDVNIEGPEGKLKGPKFKMPEM 4452 + K D+ + + D G ++ + + ++ T +V I +G L F+MP M Sbjct: 5259 ASESKSSTDIL--RCDLDSTGLKLHLSTAGMTGDELSTSEVRIHPSKGPL---PFQMPGM 5313 Query: 4453 NIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVESDLKGPEVDIE----GPEG--KLKGPK 4506 + ++ + D + L K DL E E PEG KLK Sbjct: 5314 RLPETQVLPGEID------------ETPLSKPGHDLASMEDKTEKWSSQPEGPLKLKASS 5361 Query: 4507 FKMPDVHFKSPQISMSDID-------LNLKGPKIK-GDMDISVPKLEGDLKGPKV-DVKG 4557 MP QIS+ ++D L +K PK+ P E D+ P V +V+ Sbjct: 5362 TDMPS------QISVVNVDQLWEDSVLTVKFPKLMVPRFSFPAPSSEDDVFIPTVREVQC 5415 Query: 4558 PKVGIDTP---------DIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKVK 4608 P+ IDT I + G + +L L+AP IS +V ++++G +V+ Sbjct: 5416 PEANIDTALCKESPGLWGASILKAGAGVPGEQPVDLNLPLEAPPIS--KVRVHIQGAQVE 5473 Query: 4609 GDMDISLPKVEG----DLKGPEVDIRDPKVDIDVPDVDVQGPDWHLKMPKVKMPK 4659 ++++ + DL P + ++P ++Q P + + KVK+P+ Sbjct: 5474 -SQEVTIHSIVTPEFVDLSVPRTFSTQIVRESEIPTSEIQTPSYGFSLLKVKIPE 5527 Score = 1511 bits (3912), Expect = 0.0 Identities = 1362/4593 (29%), Positives = 2079/4593 (45%), Gaps = 1145/4593 (24%) Query: 2292 EGKLKGPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVDVSAPKLEGELKGPELDVKGP 2351 + K K PKFKMP P SM + ++ PK+ + DVS ++G+LK +L V+ P Sbjct: 672 DSKFKMPKFKMPLFGASAPGKSM-EASVDVSAPKV--EADVSLLSMQGDLKTTDLSVQTP 728 Query: 2352 KLDADMPEVAV----------EGPNGKWKTPKFKMPDMHFKAPKISMPDLDLHLKSPKAK 2401 D ++ + V EG + K PK + P + K PK+ + L LK PKA+ Sbjct: 729 SADLEVQDGQVDVKLPEGPLPEGASLKGHLPKVQRPSL--KMPKVDLKGPKLDLKGPKAE 786 Query: 2402 G------------EVDVDVPKLEGDLKGPHVDVSGPDIDIEGPEGKLKGPKFKMPDMHFK 2449 EVDV P+ + D D+S D ++ + K K PKFKMP Sbjct: 787 VTAPDVKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKEVTAKDSKFKMPKFKMPSFGVS 846 Query: 2450 APNISMPDVDLNLKGPKIKGDVDVSVPEVEGKLEVPDMNIRGP---------KVDVNAPD 2500 AP SM D +++ PK++ DV +S ++G L+ D++I+ P +VDV P+ Sbjct: 847 APGKSMED-SVDVSAPKVEADVSLS--SMQGDLKATDLSIQPPSADLEVQAGQVDVKLPE 903 Query: 2501 VQAPDW---HLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDIEGPD----- 2552 P+ + +PK++MP F MP +GP++DV PK +D+ GPK ++ PD Sbjct: 904 GPVPEGAGPKVHLPKVEMPSFKMPKVDLKGPQIDVKGPK--LDLKGPKAEVTAPDGEVSL 961 Query: 2553 ----VNIEGPEGKLKGPKLK-----------MPEMNIKAPKISMPDFDLHLKGPKVKGDV 2597 V+++ + KL G L+ + K PK MP F + G +K V Sbjct: 962 PSMEVDVQAQKAKLDGAWLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIKALV 1021 Query: 2598 DVSLPKVE---------GDLKGPEVDIKGPKVD--INAPDVGVQGPDWHLK--------M 2638 DVS PKVE GDLK ++ I+ D + A V V+ P+ HL + Sbjct: 1022 DVSAPKVEADLSLPSMQGDLKTTDLSIQPASTDLKVQADQVDVKLPEGHLPEGAGLKGHL 1081 Query: 2639 PKVKMPKFSMPGFKGEGPDGDVKLPKADI-----DVSGPKVDIEGP--DVNIEGPEGKL- 2690 PKV+MP F MP +GP DVK PK D+ +V+ P V++ P +V++E P KL Sbjct: 1082 PKVEMPSFKMPKVALKGPQVDVKGPKLDLKSPKAEVTAPDVEVSLPSVEVDVEAPGAKLD 1141 Query: 2691 ----------------------KGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDVS 2728 K PKFKMP AP S+ + +++ PKV + DVS Sbjct: 1142 SARLEGELSLADKDVTAKDSRFKMPKFKMPSFGASAPGKSI-EASVDVSAPKV--EADVS 1198 Query: 2729 LPKVEGDLKGPEVDIKGPKVDID--APDVDVHGPDWHLK--------MPKIKMPKISMPG 2778 LP ++GDLK ++ I+ P D++ A VDV + H+ +PK++MP + MP Sbjct: 1199 LPSMQGDLKTTDLSIQPPSADLEVHAGQVDVKLLEGHVPEGAGFKGHLPKVQMPSLKMPK 1258 Query: 2779 FKGEGPDVDVNLPKADID------------VSGP--KVDVECPDVNIEGPE--------- 2815 +GP V+V PK D+ VS P +VD++ P ++G + Sbjct: 1259 VDLKGPQVEVRGPKLDLKGHKAEVTAHEVAVSLPSVEVDMQAPGAKLDGAQLDGDLSLAD 1318 Query: 2816 -------GKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPE 2868 K+K PKFKMP P S+ + ++L+ PK++ D+ + P ++GDLK + Sbjct: 1319 KDVTAKDSKFKMPKFKMPSFGVSAPGKSI-EASVDLSAPKVEADMSL--PSMQGDLKTTD 1375 Query: 2869 VDLKGPKVDIDVP----DVNV------QGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNL 2918 + ++ P D+++ DV + +G +PK++MP F +P +GPE+D+ Sbjct: 1376 LSIQPPSTDLELQAGQLDVKLPEGPVPEGAGLKGHLPKLQMPSFKVPKVDLKGPEIDIKG 1435 Query: 2919 PKAD-----VDVSGPKVDVEGP--DVNIEGPEGKLKGPKFK-----------MPEMNIKA 2960 PK D V+V+ P V+V P +V++E P KL G + + + K Sbjct: 1436 PKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGGRLEEDMSLADKDLTTKDSKFKM 1495 Query: 2961 PKIPMPDFDLHLKGPKVKGDVDISLPKVE---------GDLKGPEVDIRGP--------- 3002 PK MP F + G ++ VD+S PKVE GDLK ++ I+ P Sbjct: 1496 PKFKMPSFGVSAPGKSIEASVDVSAPKVEADVSLPSMQGDLKATDLSIQPPSADLEVQAG 1555 Query: 3003 QVDIDVPDVGV-QGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDID 3061 QVD+ +P+ V +G +PKV+MP F MP +GP +DV PK LD+ GPKV++ Sbjct: 1556 QVDVKLPEGPVSEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPK--LDLKGPKVEVT 1613 Query: 3062 VPDV---------NIEGPEGKLKG-----------------------PKFKMPEMNIKAP 3089 PDV +++ P KL G PKFKMP + AP Sbjct: 1614 APDVKMSLSSMEVDVQAPRAKLDGAQLEGDLSLADKAVTAKDSKFKMPKFKMPSFGVSAP 1673 Query: 3090 KISMPDIDLNLKGPKVKGDMDVSLPKVEGDMKVPDVDIKGPKVD--INAPDVDVQGPDWH 3147 S+ + +++ PKV+ D VSLP ++GD+K D+ I+ P D + A V+V+ P+ Sbjct: 1674 GKSI-EASVDVSEPKVEAD--VSLPSMQGDLKTTDLSIQSPSADLEVQAGQVNVKLPEGP 1730 Query: 3148 LK--------MPKIKMPKISMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGP- 3198 L +PK++MP + MP +GP++DV PK LD+ GPK +V PDV + P Sbjct: 1731 LPEGAGFKGHLPKVQMPSLKMPKVALKGPQMDVKGPK--LDLKGPKAEVMAPDVEVSLPS 1788 Query: 3199 -------------------------------DAKLKGPKFKMPEMNIKAPKISMPDLDLN 3227 D+K K PKFKMP + AP S+ + ++ Sbjct: 1789 VEVDVEAPGAKLDSVRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSI-EASVD 1847 Query: 3228 LKGPKMKGEVDVSLANVEGDLKGPALDIKGPKID--VDAPDIDIHGPDAKL-KGPKLKMP 3284 + PK+ E +VSL +++GDLK L I P D V A +D+ P+ ++ +G LK Sbjct: 1848 VSAPKV--EAEVSLPSMQGDLKTTDLCIPLPSADLVVQAGQVDMKLPEGQVPEGAGLKGH 1905 Query: 3285 DMHVNMPKISMPEIDLNLKGSKLKG-DVDVSGPKLEGDIKAPSLDIKGP--EVDVSGPKL 3341 V+MP MP++DL + +KG +D+ GPK E + AP +++ P EVDV K Sbjct: 1906 LPKVDMPSFKMPKVDLKGPQTDVKGAKLDLKGPKAE--VTAPDVEVSLPSMEVDVQAQKA 1963 Query: 3342 NIEGK--------------SKKSRFKLPKFNFSGSKVQTP------EVDVKGKKPDIDIT 3381 ++G +K S+FK+PKF V P VDV K + D++ Sbjct: 1964 KLDGARLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGRSIEASVDVPAPKVEADVS 2023 Query: 3382 GPKV--DINAPDVEVQGKVKGSKFKMPFLSISSP----------KVSMPDVEL-NLKSPK 3428 P + D+ D+ +Q K + + + P K +P VE+ +LK PK Sbjct: 2024 LPSMQGDLKTTDLSIQPPSADLKVQTGQVDVKLPEGHVPEGAGLKGHLPKVEMPSLKMPK 2083 Query: 3429 VKGDLDIAGPNLEGDFKGPKVDIKAPEVNLNAPDVDVHGP-------------------- 3468 V D+ GP + D KGPK+D+K P+V + PDV+V P Sbjct: 2084 V----DLKGPQV--DIKGPKLDLKDPKVEMRVPDVEVSLPSMEVDVQAPRAKLDSAHLQG 2137 Query: 3469 ------------DWNLKMPKMKMPKFSVSGL-KAEGPDVAVDLPKGDINIEGPSM--NIE 3513 D KMPK KMP F VS K+ V V PK + ++ PSM +++ Sbjct: 2138 DLTLANKDLTTKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSPPKVEADMSLPSMQGDLK 2197 Query: 3514 GPDLNV-------------------EGP---EGGLKG-------PKFKMPDMNIKAPKIS 3544 DL++ EGP E GLKG P FK+P +++K P+I Sbjct: 2198 TTDLSIQPLSADVKVQAGQVDVKLLEGPVPEEVGLKGHLPKLQMPSFKVPKVDLKGPEID 2257 Query: 3545 MPDIDLNLKGPKVK---GDVDISLPKLEGDLKGPEVDIKGPKV--DINAPDVDVHGPDWH 3599 + L+LK PKV+ DV++SLP +E D+K P + G ++ D++ D DV D Sbjct: 2258 IKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVKAPGAKLDGARLEGDMSLADKDVTAKDSK 2317 Query: 3600 LKMPKVKMPKF------------------------SMPGFKGEGPEVDVTL--PKADIDI 3633 KMPK KM F S+P +G+ D+++ P AD+++ Sbjct: 2318 FKMPKFKMLSFGVSALGKSIEASADVSALKVEADVSLPSMQGDLKTTDLSVQPPSADLEV 2377 Query: 3634 SGPNVDVDVPD------VNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLNLKGPK--- 3684 VDV +P+ ++G KL+ P FKMP++++K P+I + L+LKGPK Sbjct: 2378 QAGQVDVKLPEGPVPEGAGLKGHLPKLQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKTDV 2437 Query: 3685 MKGDVVVSLPKVEGDLKGPEVDIKGPKV--DIDTPDINIEGSEGKFKGPKFKIPEMHLKA 3742 M DV VS P VE D++ P + G + D+ D ++ + +FK PKFK+P + A Sbjct: 2438 MAPDVEVSQPSVEVDVEAPGAKLDGAWLEGDLSVADKDVTTKDSRFKIPKFKMPSFGVSA 2497 Query: 3743 PKISMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPEVDIKGPKVD--INAPDVDVQGPDW 3800 P S+ + +++ PKV + D SL M+GDLK ++ I+ P D + A VDV+ P+ Sbjct: 2498 PGKSI-EASVDVSAPKV--EADGSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEG 2554 Query: 3801 HLK--------MPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDV----- 3847 + +PKV+MP F MP +GP +DV PK LD+ GPK ++ PDV Sbjct: 2555 PVPEGAGLKGHLPKVQMPSFKMPEMDLKGPQLDVKGPK--LDLKGPKAEVTAPDVEMSLS 2612 Query: 3848 ----NIEGPEGKLKG-----------------------PKFKMPEMNIKAPKISMPDIDL 3880 +++ P KL G PKFKMP + AP S I+ Sbjct: 2613 SMEVDVQAPRAKLDGARLEGDLSLADKGVTAKDSKFKMPKFKMPSFRVSAPGES---IEA 2669 Query: 3881 NLKGPKVKGDMDVSLPKVEGDMQVPDLDIKGP--KVDINAPDVDVRGPDWHLK------- 3931 + ++K + D+SLP ++GD++ D+ I+ P ++++ A VDV+ P+ H+ Sbjct: 2670 LVDVSELKVEADMSLPSMQGDLKTTDISIQPPSAQLEVQAGQVDVKLPEGHVPEGAGLKG 2729 Query: 3932 -MPKIKMPKISMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDV---------NIEGPD 3981 +PK++MP MP +GP++DV P DL GPK +V PDV +++ P Sbjct: 2730 HLPKLQMPSFKMPEVDLKGPQIDVKGPNVDL--KGPKAEVTAPDVKMSLSSMEVDVQAPR 2787 Query: 3982 AKLKGPKFK-----------MPEMNIKAPKISMPDFDLHLKGPKVKGDVDVS-------- 4022 AKL G + + + K PK MP F + G ++ VDVS Sbjct: 2788 AKLDGARLEGDLSLADKGMTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSELKVEADG 2847 Query: 4023 -LPKMEGDLKAPEVDIKGP--KVDIDAPDVDVHGPDWHLK--------MPKVKMPKFSMP 4071 P M+GDLK ++ I+ P ++++ A VDV P+ H+ +PKV+MP F MP Sbjct: 2848 SFPSMQGDLKTTDIRIQPPSAQLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVQMPSFKMP 2907 Query: 4072 GFKGEGPEVDVNLPKADIDVSGPKVDIDTPDI---------DIHGPEGKLKG-------- 4114 +GP++DV PK +D+ GPK ++ PD+ D+ P KL G Sbjct: 2908 KVDLKGPQIDVKGPK--LDLKGPKAEVTAPDVEVSLPSVEVDVEAPRAKLDGARLEGDLS 2965 Query: 4115 ---------------PKFKMPDLHLKAPKISMPEVDLNLKGPKMKGDVDVSLPKVEGDLK 4159 PKFKMP + AP S+ EV +++ PK+ + +VSLP ++GDLK Sbjct: 2966 LADKDVTAKDSKFKMPKFKMPSFGVSAPGKSI-EVSVDVSAPKV--EAEVSLPSMQGDLK 3022 Query: 4160 GPEVDIKGPKVDIDVP--DVDVQGPDWHLK--------MPKVKMPKFSMPGFKGEGPDVD 4209 ++ I+ P ++V VD++ P+ H+ +PK++MP F MP +GP +D Sbjct: 3023 TTDISIEPPSAQLEVQAGQVDLKLPEGHVPEGAGLKGHLPKLQMPSFKMPKVDRKGPQID 3082 Query: 4210 VNLPKADLDVSGPKVDIDVPDVNIEGP--------------------------------D 4237 V PK LD+ GPK D+ PDV + P D Sbjct: 3083 VKGPK--LDLKGPKTDVTAPDVEVSQPGMEVDVEAPGAKLDGARLEGDLSLADKDVTAKD 3140 Query: 4238 AKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGP- 4296 +K K PKFKMP + AP S+ + + + PKV + D+SLP ++GDLK ++ I+ P Sbjct: 3141 SKFKMPKFKMPSFGVSAPGKSI-EVLVDVSAPKV--EADLSLPSMQGDLKNTDISIEPPS 3197 Query: 4297 -KVDIDAPDVDVHGPDWHL--------KMPKVKMPKFSMPGFKGEGPDVDVTLPKADIEI 4347 ++++ A VDV P+ H+ +PK++MP F MP +GP +D+ PK D++ Sbjct: 3198 AQLEVQAGQVDVKLPEGHVLEGAGLKGHLPKLQMPSFKMPKVDRKGPQIDIKGPKLDLK- 3256 Query: 4348 SGPKVDIDAPDVSIEGP--------------------------------DAKLKGPKFKM 4375 GPK+D+ APDV + P D+K K PKFKM Sbjct: 3257 -GPKMDVTAPDVEVSQPSMEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKM 3315 Query: 4376 PEMNIKAPKISMPDIDFNLKGPKVKGDVDVSLPKVEGDLKGPEIDIKGPSLDIDTP--DV 4433 P AP S+ ++ PK + DVSLP ++GDLK ++ I+ PS+D++ V Sbjct: 3316 PSYRASAPGKSI-QASVDVSAPKA--EADVSLPSMQGDLKTTDLSIQLPSVDLEVQAGQV 3372 Query: 4434 NIEGPEG-------------KLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVK---GDV 4477 +++ PEG K++ P FKMP++++K+P++ + L LK PK + DV Sbjct: 3373 DVKLPEGHVPEGAGLKGHLPKVEMPSFKMPKVDLKSPQVDIKGPKLDLKVPKAEVTVPDV 3432 Query: 4478 DVSLPKVESDLKGP----------------EVDIEGPEGKLKGPKFKMPDVHFKSPQISM 4521 +VSLP VE D++ P E D+ + K K PKFKMP +P S+ Sbjct: 3433 EVSLPSVEVDVQAPRAKLDGARLEGDLSLAEKDVTAKDSKFKMPKFKMPSFGVSAPGRSI 3492 Query: 4522 SDIDLNLKGPKIKGDMDISVPKLEGDLKG-------PKVDVKGPKVGIDTPDIDIHGPEG 4574 + L++ PK++ D+ +S ++GDLK P D++ V +D ++ PEG Sbjct: 3493 -EASLDVSAPKVEADVSLS--SMQGDLKATDLSIQPPSADLEVQAVQVDVELLEGPVPEG 3549 Query: 4575 --------KLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKVK---GDMDISLPKVEGDLK 4623 K++ P K P + LK P+I + L+LKGPK + D+++SLP VE D++ Sbjct: 3550 AGLKGHLPKVEMPSLKTPKVDLKGPQIDVKGPKLDLKGPKAEVRVPDVEVSLPSVEVDVQ 3609 Query: 4624 GPEVDIRDPKV--DIDVPDVDVQGPDWHLKMPKVKMPKF--SMPGFKGEGPDVDVNLPKA 4679 P+ + ++ D+ + D DV D KMPK KMP F S PG K VDV+ PK Sbjct: 3610 APKAKLDAGRLEGDLSLADKDVTAKDSKFKMPKFKMPSFRVSAPG-KSMEASVDVSAPKV 3668 Query: 4680 DIDVSGPKV--DVDVPDVNIEGPDAKLKG------------------------PKFKMPE 4713 + DVS P + D+ D++I+ P A LK PK +MP Sbjct: 3669 EADVSLPSMQGDLKTTDLSIQPPSADLKVQAGQMDVKLPEGQVPEGAGLKEHLPKVEMP- 3727 Query: 4714 MSIKAPKISMPDIDLNLKGPKVK----------GDVDVTLPKVEGDLKGPEADIKGPKV- 4762 S+K PK+ + +++KGPK+ DV+V+LP VE D++ P A + ++ Sbjct: 3728 -SLKMPKVDLKGPQVDIKGPKLDLKVSKAEVTAPDVEVSLPSVEVDVQAPRAKLDSAQLE 3786 Query: 4763 -DINTPDVDVHGPDWHLKMPKVKMPKF--SMPGFKGEGPDVDVSLPKADIDVSGPKVDVD 4819 D++ D DV D KMPK KMP F S PG K V VS PK + DVS P + D Sbjct: 3787 GDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPG-KSIEASVHVSAPKVEADVSLPSMQGD 3845 Query: 4820 IPDVNI---------------------EG---PDAKLKG-------PKFKMPEINIKAPK 4848 + ++ EG +A LKG P FKMP++++K P+ Sbjct: 3846 LKTTDLSIQPHSADLTVQARQVDMKLLEGHVPEEAGLKGHLPKVQMPSFKMPKVDLKGPE 3905 Query: 4849 ISIPDVDLDLKGPKVK---GDFDVSVPKVEGTLKGPEVDLKGPRL---------DFEGPD 4896 I I LDLK PKV+ D +VS+P VE ++ P L G RL D D Sbjct: 3906 IDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGARLEGDLSLADKDMTAKD 3965 Query: 4897 AKLSGPSLKMPSLEISAP--------KVTAPDVDLH---------LKAPKIGFSGP---- 4935 +K P KMPS +SAP VTAP V+ LKA + P Sbjct: 3966 SKFKMPKFKMPSFGVSAPGKSMEASVDVTAPKVEADVSLPSMQGDLKATDLSVQPPSADL 4025 Query: 4936 KLEGGEVDLK---GPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKFGFGAKSPKADIK 4992 +++ G+VD+K GP E SL H+ P V++P FK PK K P+ D+K Sbjct: 4026 EVQAGQVDVKLPEGPVPEGASLKGHL---------PKVQMPSFKMPKVDL--KGPQIDVK 4074 Query: 4993 SPSLDVTVPEAELNLETPEISVGGKGKKSKFKMPKIHMSGPKIKAKKQGFDLNVPGGEID 5052 P LD+ P+AE+ P++ + + + P+ + G +++ D +V + Sbjct: 4075 GPKLDLKGPKAEVT--APDVKMSLSSMEVDVQAPRAKLDGVQLEGDLSLADKDVTAKDSK 4132 Query: 5053 ASL---KAPDVDVNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEFDIKSPKFKAEAPLP 5109 + K P V+ G VDV K K + P ++ D+K+ + + Sbjct: 4133 FKMPKFKMPSFGVSAPGKSMEASVDVSELKAK----ADVSLPSMQGDLKT----TDLSIQ 4184 Query: 5110 SPKLEGELQAPDLELSLPAIHV-EGLDIKAKAPKVKMPDVDISVPKIEGDLKGPKVQANL 5168 SP + E+QA +++ LP + +G +K PKV+MP + +PK+ LKGP+V Sbjct: 4185 SPSADLEVQAGQVDVKLPEGPLPKGAGLKGHLPKVQMPC--LKMPKVA--LKGPQVDVK- 4239 Query: 5169 GAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPSVGLEGP----DVDL 5224 P ++++G A V TP +VS+P + V+++ P K D SV LEG D D+ Sbjct: 4240 -GPKLDLKGPKADVMTP-----VVEVSLPSMEVDVEAPGAKLD--SVRLEGDLSLADKDM 4291 Query: 5225 QGPEAKIKFPKFSMPKIGI--PGVKMEGG------GAEVHAQLPSLEGDLRGP------- 5269 ++K K PKF MP G+ PG +E E LPS++GDL+ Sbjct: 4292 TAKDSKFKMPKFKMPSFGVSAPGKSIEASLDVSALKVEADVSLPSMQGDLKTTHLSIQPP 4351 Query: 5270 -----------DVKL-EGP---DVSLKG--PGVDLPSVNLSMPKVSGPDLDLN-----LK 5307 DVKL EGP LKG P + +PS + + GP +D+N LK Sbjct: 4352 SADLEVQAGQEDVKLPEGPVHEGAGLKGHLPKLQMPSFKVPKVDLKGPQIDVNVPKLDLK 4411 Query: 5308 GPSLK---GDLDASVPSMKV--HAPGLNLSGVG---------------------GKMQVG 5341 GP ++ +LD S+PSM+V APG L K ++ Sbjct: 4412 GPKVEVTSPNLDVSLPSMEVDIQAPGAKLDSTRLEGDLSLADKDVTAKDSKFKMPKFKMP 4471 Query: 5342 GDGVKVPGIDATTKLNVGAP--DVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEG 5399 G+ PG ++V AP + + PS+QGDL + D++ + + DL ++A + Sbjct: 4472 SFGMLSPGKSIEVSVDVSAPKMEADMSIPSMQGDLKTT-DLR---IQAPSADLEVQAGQV 4527 Query: 5400 SIKLPKMKLPQFG--------ISTPGSDL-HVNAKGPQVSGELKGPGVDVNLKGPR--IS 5448 +KLP+ +P+ + P + V+ KGPQV ++KGP +D LKGP+ + Sbjct: 4528 DLKLPEGHMPEVAGLKGHLPKVEMPSFKMPKVDLKGPQV--DVKGPKLD--LKGPKAEVM 4583 Query: 5449 APNVDFNLEGPKVKGSLGATGE-IKGPTVGGGL----------------PGIGVQGLEGN 5491 AP+V+ +L P V+ + A G + G + G L P + G E + Sbjct: 4584 APDVEVSL--PSVETDVQAPGSMLDGARLEGDLSLAHEDVAGKDSKFQGPKLSTSGFEWS 4641 Query: 5492 LQMPGIKSSGCDVNL---------PGVNVKLPTGQISGPEIKG--GLKGSEVGFHGAAPD 5540 + + SS + N+ P V + G + P G GL EVG Sbjct: 4642 SKKVSMSSSEIEGNVTFHEKTSTFPIVESVVHEGDLHDPSRDGNLGLAVGEVGMDSKFKK 4701 Query: 5541 ISVKGPAFNMASPESDFGINLKGPK--IKGGADVSGGVSAPDISLGEGHLSVKGSGGEWK 5598 + K P + +S K PK + GA S G+S +S E ++ Sbjct: 4702 LHFKVPKVSFSST--------KTPKDSLVPGAKSSIGLSTIPLSSSEC--------SSFE 4745 Query: 5599 GPQVSS----ALNLDTSKFAG----GLHFSGPKVEGGV---------------------- 5628 QVS+ ++ + FAG L +GP E + Sbjct: 4746 LQQVSACSEPSMQMPKVGFAGFPSSRLDLTGPHFESSILSPCEDVTLTKYQVTVPRAALA 4805 Query: 5629 --------KGGQIGLQAPGLSVSG--------PQGHLESGSG-----------KVTFPKM 5661 G Q + P S P ES SG +V+FPK Sbjct: 4806 PELALEIPSGSQADIPLPKTECSTDLQPPEGVPTSQAESHSGPLNSMIPVSLGQVSFPKF 4865 Query: 5662 KIPKFTFSGRELVGRE------MGVDVHFPKAE--------------------------- 5688 PKF FS ++ E +G V P + Sbjct: 4866 YKPKFVFSVPQMAVPEGDLHAAVGAPVMSPLSPGERVQCPLPSTQLPSPGTCVSQGPEEL 4925 Query: 5689 -ASIQ--------AGAGDGEWEESEVKLKKSKIKMPKFNFSKPKGKGGVTGSPEASISGS 5739 AS+Q A + D + E LK KIK+P F +S PK + G PE S+ S Sbjct: 4926 VASLQTSVVAPGEAPSEDADHEGKGSPLKMPKIKLPSFRWS-PKKETGPKVDPECSVEDS 4984 Query: 5740 KGDL---KSSKASLGSLEGEAEAEASSPKGK-----FSLFKSKKPRHRSNSFSDEREFSG 5791 K L K A ++ + E KG+ F++ K P+ +++ SG Sbjct: 4985 KLSLVLDKDEVAPQSAIHMDLPPERDGEKGRSTKPGFAMPKLALPKMKASK-------SG 5037 Query: 5792 PSTPTGTLEFEGGEVSLEGGKVKGKHGKLKFGTFGGLGSKSKGHYEVTGSDD-ETGKLQG 5850 S P ++ + GG + G GGLG+ + TGS+ + Q Sbjct: 5038 VSLPQRDVD-PSLSSATAGGSFQDTEKASSDGGRGGLGATA----SATGSEGVNLHRPQV 5092 Query: 5851 SGVSLASKKSRLSSSSSNDSGNKVGIQLPEVEL 5883 SL K L SS + KV + PE +L Sbjct: 5093 HIPSLGFAKPDLRSSKA-----KVEVSQPEADL 5120 Score = 1418 bits (3671), Expect = 0.0 Identities = 1280/4459 (28%), Positives = 1980/4459 (44%), Gaps = 1121/4459 (25%) Query: 2274 VSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVDVS 2333 + P++ V V D L+ P+ K E TP+ + G +KG+ Sbjct: 477 IGPPEIRVRVHD--LKTPKFAFSTEKEPERERRLSTPQRGKRQDASSKAGTGLKGEEVEG 534 Query: 2334 APKLEGELKGPELDVKGPKLDADM----------PEVAVEGPNGKWKTPKFKMPDMHFKA 2383 A + G + +G + D + + E G+ + PKFK+P + + Sbjct: 535 AGWMPGREPTTHAEAQGDEGDGEEGLQRTRITEEQDKGREDTEGQIRMPKFKIPSLGWSP 594 Query: 2384 PKISMPDLDLHLKSPKAKGEVDVDVPKLEGDLKGPHVDVSGPDIDIEGPEGKLKGPKFKM 2443 K H K+ + K D + +G EG+ + Sbjct: 595 SK--------HTKTGREKATEDTE----------------------QGREGEATATADRR 624 Query: 2444 PDMHFKAPNISMPDVDLNLKGPKIKGDVDVSVPEVEGKLEVPDMNIRGPKVDVNAPDVQA 2503 + +G K K D D + +L + ++ ++ + +V Sbjct: 625 EQRRTE-------------EGLKDKEDSDSMTNTTKIQLIHDEKRLKKEQI-LTEKEVAT 670 Query: 2504 PDWHLKMPKMKMPKF--SMPGFKAEGPEVDVNLPKADVDIS--GPKVDIEGPDVNIEGPE 2559 D KMPK KMP F S PG E VDV+ PK + D+S + D++ D++++ P Sbjct: 671 KDSKFKMPKFKMPLFGASAPGKSMEA-SVDVSAPKVEADVSLLSMQGDLKTTDLSVQTPS 729 Query: 2560 GKLKGPKLKMPEMNIKAPKISMPDFDLHLKG--PKVKGDVDVSLPKVEGDLKGPEVDIKG 2617 L+ ++ ++++K P+ +P+ LKG PKV+ + +PKV DLKGP++D+KG Sbjct: 730 ADLE---VQDGQVDVKLPEGPLPE-GASLKGHLPKVQRP-SLKMPKV--DLKGPKLDLKG 782 Query: 2618 PKVDINAPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPKVDIE 2677 PK ++ APDV KM SM + DV+ P+A +D + + D+ Sbjct: 783 PKAEVTAPDV--------------KMSLSSM--------EVDVQAPRAKLDGARLEGDLS 820 Query: 2678 GPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGDLK 2737 D + + K K PKFKMP + AP SM D +++ PKV + DVSL ++GDLK Sbjct: 821 LADKEVTAKDSKFKMPKFKMPSFGVSAPGKSMED-SVDVSAPKV--EADVSLSSMQGDLK 877 Query: 2738 GPEVDIKGPKVDID--APDVDVHGPDWHLKM---PKIKMPKISMPGFKG-----EGPDVD 2787 ++ I+ P D++ A VDV P+ + PK+ +PK+ MP FK +GP +D Sbjct: 878 ATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGPKVHLPKVEMPSFKMPKVDLKGPQID 937 Query: 2788 VNLPKADIDVSGPKVDVECPDVNIEGP-------------EGKWKSPKFKMPEMH----- 2829 V PK +D+ GPK +V PD + P +G W + + Sbjct: 938 VKGPK--LDLKGPKAEVTAPDGEVSLPSMEVDVQAQKAKLDGAWLEGDLSLADKDVTAKD 995 Query: 2830 --FKTPKISMPDIDLNLTGPKIKGDVDVTGPKVE---------GDLKGPEVDLKGPKVDI 2878 FK PK MP ++ G IK VDV+ PKVE GDLK ++ ++ D+ Sbjct: 996 SKFKMPKFKMPSFGVSAPGKSIKALVDVSAPKVEADLSLPSMQGDLKTTDLSIQPASTDL 1055 Query: 2879 DVP--DVNVQGPDWHLK--------MPKMKMPKFSMPGFKAEGPEVDVNLPKADV----- 2923 V V+V+ P+ HL +PK++MP F MP +GP+VDV PK D+ Sbjct: 1056 KVQADQVDVKLPEGHLPEGAGLKGHLPKVEMPSFKMPKVALKGPQVDVKGPKLDLKSPKA 1115 Query: 2924 DVSGPKVDVEGP--DVNIEGPEGKLKGPKFK-----------MPEMNIKAPKIPMPDFDL 2970 +V+ P V+V P +V++E P KL + + + K PK MP F Sbjct: 1116 EVTAPDVEVSLPSVEVDVEAPGAKLDSARLEGELSLADKDVTAKDSRFKMPKFKMPSFGA 1175 Query: 2971 HLKGPKVKGDVDISLPKVE---------GDLKGPEVDIRGPQVDIDVP----DVGV---- 3013 G ++ VD+S PKVE GDLK ++ I+ P D++V DV + Sbjct: 1176 SAPGKSIEASVDVSAPKVEADVSLPSMQGDLKTTDLSIQPPSADLEVHAGQVDVKLLEGH 1235 Query: 3014 --QGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLD------------VSGPKVD 3059 +G + +PKV+MP MP +GP V+V PK DL VS P V+ Sbjct: 1236 VPEGAGFKGHLPKVQMPSLKMPKVDLKGPQVEVRGPKLDLKGHKAEVTAHEVAVSLPSVE 1295 Query: 3060 IDVP------------------DVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLK 3101 +D+ D ++ + K K PKFKMP + AP S+ + ++L Sbjct: 1296 VDMQAPGAKLDGAQLDGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSI-EASVDLS 1354 Query: 3102 GPKVKGDMDVSLPKVEGDMKVPDVDIKGPKVDIN--APDVDVQGPDWHLK--------MP 3151 PKV+ DM SLP ++GD+K D+ I+ P D+ A +DV+ P+ + +P Sbjct: 1355 APKVEADM--SLPSMQGDLKTTDLSIQPPSTDLELQAGQLDVKLPEGPVPEGAGLKGHLP 1412 Query: 3152 KIKMPKISMPGFKGEGPEVDVNLPKADL-----DVSGPKVDVDVP--DVNIEGPDAKLKG 3204 K++MP +P +GPE+D+ PK DL +V+ P V+V +P +V++E P AKL G Sbjct: 1413 KLQMPSFKVPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDG 1472 Query: 3205 -----------------------PKFKMPEMNIKAP-----------------KISMPDL 3224 PKFKMP + AP +S+P + Sbjct: 1473 GRLEEDMSLADKDLTTKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSAPKVEADVSLPSM 1532 Query: 3225 -------DLNLKGPK-----MKGEVDVSL--------ANVEG------------------ 3246 DL+++ P G+VDV L A ++G Sbjct: 1533 QGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVSEGAGLKGHLPKVQMPSFKMPKVDLK 1592 Query: 3247 ----DLKGPALDIKGPKIDVDAPDI---------DIHGPDAKLKGPKLK----------- 3282 D+KGP LD+KGPK++V APD+ D+ P AKL G +L+ Sbjct: 1593 GPQIDVKGPKLDLKGPKVEVTAPDVKMSLSSMEVDVQAPRAKLDGAQLEGDLSLADKAVT 1652 Query: 3283 MPDMHVNMPKISMPEIDLNLKGSKLKGDVDVSGPKLEGDIKAPSL--DIKGPEVDVSGPK 3340 D MPK MP ++ G ++ VDVS PK+E D+ PS+ D+K ++ + P Sbjct: 1653 AKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSEPKVEADVSLPSMQGDLKTTDLSIQSPS 1712 Query: 3341 LNIEGKSKKSRFKLPK------FNFSGS--KVQTP------------EVDVKGKKPDIDI 3380 ++E ++ + KLP+ F G KVQ P ++DVKG P +D+ Sbjct: 1713 ADLEVQAGQVNVKLPEGPLPEGAGFKGHLPKVQMPSLKMPKVALKGPQMDVKG--PKLDL 1770 Query: 3381 TGPKVDINAPDVEVQ-----------------------------------GKVKGSKFKM 3405 GPK ++ APDVEV K K KFKM Sbjct: 1771 KGPKAEVMAPDVEVSLPSVEVDVEAPGAKLDSVRLEGDLSLADKDVTAKDSKFKMPKFKM 1830 Query: 3406 PFLSISSPKVSMPDVELNLKSPKVKGDLDIAGPNLEGDFKGPKVDIKAPEVNL--NAPDV 3463 P +S+P S+ + +++ +PKV+ ++ + P+++GD K + I P +L A V Sbjct: 1831 PSFGVSAPGKSI-EASVDVSAPKVEAEVSL--PSMQGDLKTTDLCIPLPSADLVVQAGQV 1887 Query: 3464 DVHGPDWNLK-------------MPKMKMPK--------------FSVSGLKAE--GPDV 3494 D+ P+ + MP KMPK + G KAE PDV Sbjct: 1888 DMKLPEGQVPEGAGLKGHLPKVDMPSFKMPKVDLKGPQTDVKGAKLDLKGPKAEVTAPDV 1947 Query: 3495 AVDLPKGDINIEGPSMNIEGP---------DLNVEGPEGGLKGPKFKMPDMNIKAPKISM 3545 V LP +++++ ++G D ++ + K PKFKMP + AP S+ Sbjct: 1948 EVSLPSMEVDVQAQKAKLDGARLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGRSI 2007 Query: 3546 PDIDLNLKGPKVKGDVDISLPKLEGDLKGPEVDIKGPKVDINAP--DVDVHGPDWHLK-- 3601 + +++ PKV+ DV SLP ++GDLK ++ I+ P D+ VDV P+ H+ Sbjct: 2008 -EASVDVPAPKVEADV--SLPSMQGDLKTTDLSIQPPSADLKVQTGQVDVKLPEGHVPEG 2064 Query: 3602 ------MPKVKMPKFSMPGFKGEGPEVDVTLPKADIDISGPNVDVDVPDVNIEGP----- 3650 +PKV+MP MP +GP+VD+ PK +D+ P V++ VPDV + P Sbjct: 2065 AGLKGHLPKVEMPSLKMPKVDLKGPQVDIKGPK--LDLKDPKVEMRVPDVEVSLPSMEVD 2122 Query: 3651 ---------------------------DAKLKGPKFKMPEMNIKAPKISMPDFDLNLKGP 3683 D+K K PKFKMP + AP S+ + +++ P Sbjct: 2123 VQAPRAKLDSAHLQGDLTLANKDLTTKDSKFKMPKFKMPSFGVSAPGKSI-EASVDVSPP 2181 Query: 3684 KMKGDVVVSLPKVEGDLKGPEVDIKGPKVDIDTP---------------DINIEGSEGKF 3728 K++ D+ SLP ++GDLK ++ I+ D+ ++ ++G K Sbjct: 2182 KVEADM--SLPSMQGDLKTTDLSIQPLSADVKVQAGQVDVKLLEGPVPEEVGLKGHLPKL 2239 Query: 3729 KGPKFKIPEMHLKAPKISMPDIDLNLKGPKVK---GDVDVSLPKMEGDLKGPEVDIKGPK 3785 + P FK+P++ LK P+I + L+LK PKV+ DV+VSLP +E D+K P + G + Sbjct: 2240 QMPSFKVPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVKAPGAKLDGAR 2299 Query: 3786 V--DINAPDVDVQGPDWHLKMPKVKMPKF------------------------SMPGFKG 3819 + D++ D DV D KMPK KM F S+P +G Sbjct: 2300 LEGDMSLADKDVTAKDSKFKMPKFKMLSFGVSALGKSIEASADVSALKVEADVSLPSMQG 2359 Query: 3820 E--GPDVDVNLPKADLDVSGPKVDIDVPD------VNIEGPEGKLKGPKFKMPEMNIKAP 3871 + D+ V P ADL+V +VD+ +P+ ++G KL+ P FKMP++++K P Sbjct: 2360 DLKTTDLSVQPPSADLEVQAGQVDVKLPEGPVPEGAGLKGHLPKLQMPSFKMPKVDLKGP 2419 Query: 3872 KISMPDIDLNLKGPK---VKGDMDVSLPKVEGDMQVPDLDIKGPKV--DINAPDVDVRGP 3926 +I + L+LKGPK + D++VS P VE D++ P + G + D++ D DV Sbjct: 2420 QIDVKGPKLDLKGPKTDVMAPDVEVSQPSVEVDVEAPGAKLDGAWLEGDLSVADKDVTTK 2479 Query: 3927 DWHLKMPKIKMPK--ISMPGFKGEGPEVDVNLPK-------------------------A 3959 D K+PK KMP +S PG K VDV+ PK A Sbjct: 2480 DSRFKIPKFKMPSFGVSAPG-KSIEASVDVSAPKVEADGSLSSMQGDLKATDLSIQPPSA 2538 Query: 3960 DLDVSGPKVDVDVPD------VNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGP 4013 DL+V +VDV +P+ ++G K++ P FKMPEM++K P++ + L LKGP Sbjct: 2539 DLEVQAGQVDVKLPEGPVPEGAGLKGHLPKVQMPSFKMPEMDLKGPQLDVKGPKLDLKGP 2598 Query: 4014 KVK---GDVDVSLPKMEGDLKAPEVDIKGPKV--DIDAPDVDVHGPDWHLKMPKVKMPKF 4068 K + DV++SL ME D++AP + G ++ D+ D V D KMPK KMP F Sbjct: 2599 KAEVTAPDVEMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGVTAKDSKFKMPKFKMPSF 2658 Query: 4069 ------------------------SMPGFKGEGPEVDVNL--PKADIDVSGPKVDIDTPD 4102 S+P +G+ D+++ P A ++V +VD+ P+ Sbjct: 2659 RVSAPGESIEALVDVSELKVEADMSLPSMQGDLKTTDISIQPPSAQLEVQAGQVDVKLPE 2718 Query: 4103 IDIHGPEG--------KLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKMK---GDVDVSL 4151 H PEG KL+ P FKMP++ LK P+I + +++LKGPK + DV +SL Sbjct: 2719 G--HVPEGAGLKGHLPKLQMPSFKMPEVDLKGPQIDVKGPNVDLKGPKAEVTAPDVKMSL 2776 Query: 4152 PKVEGDLKGPEVDIKGPKV--DIDVPDVDVQGPDWHLKMPKVKMPKF------------- 4196 +E D++ P + G ++ D+ + D + D KMPK KMP F Sbjct: 2777 SSMEVDVQAPRAKLDGARLEGDLSLADKGMTAKDSKFKMPKFKMPSFGVSAPGKSIEASV 2836 Query: 4197 -----------SMPGFKGEGPDVDVNL--PKADLDVSGPKVDIDVPD------VNIEGPD 4237 S P +G+ D+ + P A L+V +VD+ +P+ ++G Sbjct: 2837 DVSELKVEADGSFPSMQGDLKTTDIRIQPPSAQLEVQAGQVDVKLPEGHVPEGAGLKGHL 2896 Query: 4238 AKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVK---GDVDVSLPKVEGDLKGPEVDIK 4294 K++ P FKMP++++K P+I + L LKGPK + DV+VSLP VE D++ P + Sbjct: 2897 PKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDVEVSLPSVEVDVEAPRAKLD 2956 Query: 4295 GPKV--DIDAPDVDVHGPDWHLKMPKVKMPKF--SMPGFKGEGPDVDVTLPKADIEISGP 4350 G ++ D+ D DV D KMPK KMP F S PG K VDV+ PK + E+S P Sbjct: 2957 GARLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPG-KSIEVSVDVSAPKVEAEVSLP 3015 Query: 4351 KV--DIDAPDVSIEGPDA-----------------------------KLKGPKFKMPEMN 4379 + D+ D+SIE P A KL+ P FKMP+++ Sbjct: 3016 SMQGDLKTTDISIEPPSAQLEVQAGQVDLKLPEGHVPEGAGLKGHLPKLQMPSFKMPKVD 3075 Query: 4380 IKAPKISMPDIDFNLKGPKVK---GDVDVSLPKVEGDLKGPEIDIKGPSL--DIDTPDVN 4434 K P+I + +LKGPK DV+VS P +E D++ P + G L D+ D + Sbjct: 3076 RKGPQIDVKGPKLDLKGPKTDVTAPDVEVSQPGMEVDVEAPGAKLDGARLEGDLSLADKD 3135 Query: 4435 IEGPEGKLKGPKFKMPEMNIKAP--------KISMPDFDLHLKGPKVKGDV---DVSL-- 4481 + + K K PKFKMP + AP +S P + L P ++GD+ D+S+ Sbjct: 3136 VTAKDSKFKMPKFKMPSFGVSAPGKSIEVLVDVSAPKVEADLSLPSMQGDLKNTDISIEP 3195 Query: 4482 PKVESDLKGPEVDIEGPEG-------------KLKGPKFKMPDVHFKSPQISMSDIDLNL 4528 P + +++ +VD++ PEG KL+ P FKMP V K PQI + L+L Sbjct: 3196 PSAQLEVQAGQVDVKLPEGHVLEGAGLKGHLPKLQMPSFKMPKVDRKGPQIDIKGPKLDL 3255 Query: 4529 KGPKIK---GDMDISVPKLEGDLKGPKVDVKGPKV--GIDTPDIDIHGPEGKLKGPKFKM 4583 KGPK+ D+++S P +E D++ P + G ++ + D D+ + K K PKFKM Sbjct: 3256 KGPKMDVTAPDVEVSQPSMEVDVEAPGAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKM 3315 Query: 4584 PDLHLKAPKISMPEVDLNLKGPKVKGDMDISLPKVEGDLKGPEVDIRDPKVDIDVP--DV 4641 P AP S+ + +++ PK + D +SLP ++GDLK ++ I+ P VD++V V Sbjct: 3316 PSYRASAPGKSI-QASVDVSAPKAEAD--VSLPSMQGDLKTTDLSIQLPSVDLEVQAGQV 3372 Query: 4642 DVQGPDWHLK--------MPKVKMPKFSMPGFKGEGPDVDVNLPKADIDVSGPKVDVDVP 4693 DV+ P+ H+ +PKV+MP F MP + P VD+ PK D+ V PK +V VP Sbjct: 3373 DVKLPEGHVPEGAGLKGHLPKVEMPSFKMPKVDLKSPQVDIKGPKLDLKV--PKAEVTVP 3430 Query: 4694 DVNIEGP--------------------------------DAKLKGPKFKMPEMSIKAPKI 4721 DV + P D+K K PKFKMP + AP Sbjct: 3431 DVEVSLPSVEVDVQAPRAKLDGARLEGDLSLAEKDVTAKDSKFKMPKFKMPSFGVSAPGR 3490 Query: 4722 SMPDIDLNLKGPKVKGDVDVTLPKVEGDLKG-------PEADI----------------- 4757 S+ + L++ PKV + DV+L ++GDLK P AD+ Sbjct: 3491 SI-EASLDVSAPKV--EADVSLSSMQGDLKATDLSIQPPSADLEVQAVQVDVELLEGPVP 3547 Query: 4758 -----------------KGPKVDINTPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDV 4800 K PKVD+ P +DV GP LK PK ++ PDV Sbjct: 3548 EGAGLKGHLPKVEMPSLKTPKVDLKGPQIDVKGPKLDLKGPKAEV----------RVPDV 3597 Query: 4801 DVSLPKADIDVSGPKV---------DVDIPDVNIEGPDAKLKGPKFKMPEINIKAPKISI 4851 +VSLP ++DV PK D+ + D ++ D+K K PKFKMP + AP S+ Sbjct: 3598 EVSLPSVEVDVQAPKAKLDAGRLEGDLSLADKDVTAKDSKFKMPKFKMPSFRVSAPGKSM 3657 Query: 4852 PDVDLDLKGPKVKGDFDVSVPKVEGTLKGPEVDLKGP---------RLDFEGPDA----- 4897 + +D+ PKV+ D VS+P ++G LK ++ ++ P ++D + P+ Sbjct: 3658 -EASVDVSAPKVEAD--VSLPSMQGDLKTTDLSIQPPSADLKVQAGQMDVKLPEGQVPEG 3714 Query: 4898 --------KLSGPSLKMPSLEISAPKVTAPDVDLHLKAPKIGFSGPKLEGG----EVDLK 4945 K+ PSLKMP +++ P+V L LK K + P +E EVD++ Sbjct: 3715 AGLKEHLPKVEMPSLKMPKVDLKGPQVDIKGPKLDLKVSKAEVTAPDVEVSLPSVEVDVQ 3774 Query: 4946 GPKVEAPSL----DVHMDSPDINIEGPDVKIPKFKKPKFGFGA--KSPKADI--KSPSL- 4996 P+ + S D+ + D+ + K+PKFK P FG A KS +A + +P + Sbjct: 3775 APRAKLDSAQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVHVSAPKVE 3834 Query: 4997 -DVTVPEAELNLETPEISV---------------------------GGKGKKSK-----F 5023 DV++P + +L+T ++S+ G KG K F Sbjct: 3835 ADVSLPSMQGDLKTTDLSIQPHSADLTVQARQVDMKLLEGHVPEEAGLKGHLPKVQMPSF 3894 Query: 5024 KMPKIHMSGPKIKAKKQGFDLNVPGGEI---DASLKAPDVDVNIAGPDAALK-------- 5072 KMPK+ + GP+I K DL P E+ D + P V+V++ P A L Sbjct: 3895 KMPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGARLEGDL 3954 Query: 5073 -----------VDVKSPKTKKTMFGKMY---FPDVEFDIKSPKFKAEAPLPSPKLEGELQ 5118 K PK K FG + D+ +PK +A+ LPS ++G+L+ Sbjct: 3955 SLADKDMTAKDSKFKMPKFKMPSFGVSAPGKSMEASVDVTAPKVEADVSLPS--MQGDLK 4012 Query: 5119 APDLELSLPAIHVE-----------------GLDIKAKAPKVKMPDVDISVPKIEGDLKG 5161 A DL + P+ +E G +K PKV+MP +PK+ DLKG Sbjct: 4013 ATDLSVQPPSADLEVQAGQVDVKLPEGPVPEGASLKGHLPKVQMPS--FKMPKV--DLKG 4068 Query: 5162 PKVQANLGAPDINIEGLDAKVKTPS--FGISAPQVSIPDVNVNLKGPKIKGDVPSVGLEG 5219 P++ P ++++G A+V P +S+ +V + L G +++GD L Sbjct: 4069 PQIDVK--GPKLDLKGPKAEVTAPDVKMSLSSMEVDVQAPRAKLDGVQLEGD-----LSL 4121 Query: 5220 PDVDLQGPEAKIKFPKFSMPKIGI--PGVKMEGG------GAEVHAQLPSLEGDLRGPDV 5271 D D+ ++K K PKF MP G+ PG ME A+ LPS++GDL+ D+ Sbjct: 4122 ADKDVTAKDSKFKMPKFKMPSFGVSAPGKSMEASVDVSELKAKADVSLPSMQGDLKTTDL 4181 Query: 5272 KLEGPDVSL-----------------KGPGVD--LPSVN---LSMPKVS--GPDLD---- 5303 ++ P L KG G+ LP V L MPKV+ GP +D Sbjct: 4182 SIQSPSADLEVQAGQVDVKLPEGPLPKGAGLKGHLPKVQMPCLKMPKVALKGPQVDVKGP 4241 Query: 5304 -LNLKGPS---LKGDLDASVPSMKV--HAPGLNLSGVG---------------------G 5336 L+LKGP + ++ S+PSM+V APG L V Sbjct: 4242 KLDLKGPKADVMTPVVEVSLPSMEVDVEAPGAKLDSVRLEGDLSLADKDMTAKDSKFKMP 4301 Query: 5337 KMQVGGDGVKVPGIDATTKLNVGA----PDVTLRGPSLQGDLAVSGDIKCPKVSVGAP-- 5390 K ++ GV PG L+V A DV+L PS+QGDL K +S+ P Sbjct: 4302 KFKMPSFGVSAPGKSIEASLDVSALKVEADVSL--PSMQGDL------KTTHLSIQPPSA 4353 Query: 5391 DLSLEASEGSIKLP---------------KMKLPQFGISTPGSDLHVNAKGPQVSG---- 5431 DL ++A + +KLP K+++P F + V+ KGPQ+ Sbjct: 4354 DLEVQAGQEDVKLPEGPVHEGAGLKGHLPKLQMPSFKVPK------VDLKGPQIDVNVPK 4407 Query: 5432 -ELKGPGVDVNLKGPRISAPNVDFNLEGPKVK-GSLGATGEIKGPTVGGGLPGIGVQGLE 5489 +LKGP V+V +S P+++ +++ P K S G++ L V + Sbjct: 4408 LDLKGPKVEVTSPNLDVSLPSMEVDIQAPGAKLDSTRLEGDLS-------LADKDVTAKD 4460 Query: 5490 GNLQMPGIKSSGCDVNLPGVNVKLPT--------GQISGPEIKGGLKGSEVGFHGAAPDI 5541 +MP K + PG ++++ +S P ++G LK +++ + D+ Sbjct: 4461 SKFKMPKFKMPSFGMLSPGKSIEVSVDVSAPKMEADMSIPSMQGDLKTTDLRIQAPSADL 4520 Query: 5542 SVKGPAFNMASPESDFG--INLKG--PKIKGGADVSGGVS--APDISLGEGHLSVKGSGG 5595 V+ ++ PE LKG PK++ + V P + + L +KG Sbjct: 4521 EVQAGQVDLKLPEGHMPEVAGLKGHLPKVEMPSFKMPKVDLKGPQVDVKGPKLDLKGPKA 4580 Query: 5596 EWKGPQVSSAL-NLDTSKFAGGLHFSGPKVEGG-------VKGGQIGLQAPGLSVSGPQG 5647 E P V +L +++T A G G ++EG V G Q P LS SG + Sbjct: 4581 EVMAPDVEVSLPSVETDVQAPGSMLDGARLEGDLSLAHEDVAGKDSKFQGPKLSTSGFEW 4640 Query: 5648 HLESGS-------GKVTFPKMKIPKFTFSGRELVGREMGVDVHFPKAEASIQAGAGDGEW 5700 + S G VTF + TF E V E D+H P + ++ G+ Sbjct: 4641 SSKKVSMSSSEIEGNVTFHEKTS---TFPIVESVVHEG--DLHDPSRDGNLGLAVGEVGM 4695 Query: 5701 EESEVKLKKSKIKMPKFNFSKPK-GKGGVTGSPEASISGSKGDLKSSKAS---LGSLEGE 5756 + K KK K+PK +FS K K + ++SI S L SS+ S L + Sbjct: 4696 DS---KFKKLHFKVPKVSFSSTKTPKDSLVPGAKSSIGLSTIPLSSSECSSFELQQVSAC 4752 Query: 5757 AEAEASSPKGKFSLFKSKK 5775 +E PK F+ F S + Sbjct: 4753 SEPSMQMPKVGFAGFPSSR 4771 Score = 1358 bits (3514), Expect = 0.0 Identities = 1207/4111 (29%), Positives = 1857/4111 (45%), Gaps = 1059/4111 (25%) Query: 2637 KMPKVKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKLKGPKFK 2696 K K KMPKF MP F P K +A +DVS PKV+ DV++ +G LK Sbjct: 671 KDSKFKMPKFKMPLFGASAPG---KSMEASVDVSAPKVEA---DVSLLSMQGDLK----- 719 Query: 2697 MPEMNIKAPKISMP----DIDLNL-KGPKVKG-DVDVSLPKVEG-DLKGPEVDIKGPKVD 2749 +++++ P + +D+ L +GP +G + LPKV+ LK P+VD+KGPK+D Sbjct: 720 TTDLSVQTPSADLEVQDGQVDVKLPEGPLPEGASLKGHLPKVQRPSLKMPKVDLKGPKLD 779 Query: 2750 IDAPDVDVHGPDWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDV 2809 + P +V PD +KM SM +VDV P+A +D + + D+ D Sbjct: 780 LKGPKAEVTAPD-------VKMSLSSM--------EVDVQAPRAKLDGARLEGDLSLADK 824 Query: 2810 NIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPEV 2869 + + K+K PKFKMP P SM D ++++ PK++ DV ++ ++GDLK ++ Sbjct: 825 EVTAKDSKFKMPKFKMPSFGVSAPGKSMED-SVDVSAPKVEADVSLSS--MQGDLKATDL 881 Query: 2870 DLKGPKVDIDVPDVNVQ------------GPDWHLKMPKMKMPKFSMPGFKAEGPEVDVN 2917 ++ P D++V V GP HL PK++MP F MP +GP++DV Sbjct: 882 SIQPPSADLEVQAGQVDVKLPEGPVPEGAGPKVHL--PKVEMPSFKMPKVDLKGPQIDVK 939 Query: 2918 LPKADVDVSGPKVDVEGPD---------VNIEGPEGKLKGPKFK-----------MPEMN 2957 PK +D+ GPK +V PD V+++ + KL G + + Sbjct: 940 GPK--LDLKGPKAEVTAPDGEVSLPSMEVDVQAQKAKLDGAWLEGDLSLADKDVTAKDSK 997 Query: 2958 IKAPKIPMPDFDLHLKGPKVKGDVDISLPKVE---------GDLKGPEVDIRGPQVDIDV 3008 K PK MP F + G +K VD+S PKVE GDLK ++ I+ D+ V Sbjct: 998 FKMPKFKMPSFGVSAPGKSIKALVDVSAPKVEADLSLPSMQGDLKTTDLSIQPASTDLKV 1057 Query: 3009 P--DVGVQGPDWHLK--------MPKVKMPKFSMPGFKGEGPDVDVNLPKADL-----DV 3053 V V+ P+ HL +PKV+MP F MP +GP VDV PK DL +V Sbjct: 1058 QADQVDVKLPEGHLPEGAGLKGHLPKVEMPSFKMPKVALKGPQVDVKGPKLDLKSPKAEV 1117 Query: 3054 SGPKVDIDVP--DVNIEGPEGKL-----------------------KGPKFKMPEMNIKA 3088 + P V++ +P +V++E P KL K PKFKMP A Sbjct: 1118 TAPDVEVSLPSVEVDVEAPGAKLDSARLEGELSLADKDVTAKDSRFKMPKFKMPSFGASA 1177 Query: 3089 PKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMKVPDVDIKGPKVD--INAPDVDVQGPDW 3146 P S+ + +++ PKV+ D VSLP ++GD+K D+ I+ P D ++A VDV+ + Sbjct: 1178 PGKSI-EASVDVSAPKVEAD--VSLPSMQGDLKTTDLSIQPPSADLEVHAGQVDVKLLEG 1234 Query: 3147 HLK--------MPKIKMPKISMPGFKGEGPEVDVNLPKADLD------------VSGPKV 3186 H+ +PK++MP + MP +GP+V+V PK DL VS P V Sbjct: 1235 HVPEGAGFKGHLPKVQMPSLKMPKVDLKGPQVEVRGPKLDLKGHKAEVTAHEVAVSLPSV 1294 Query: 3187 DVDVP------------------DVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDLDLNL 3228 +VD+ D ++ D+K K PKFKMP + AP S+ + ++L Sbjct: 1295 EVDMQAPGAKLDGAQLDGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSI-EASVDL 1353 Query: 3229 KGPKMKGEVDVSLANVEGDLKGPALDIKGPKIDVD--APDIDIHGPD------AKLKG-- 3278 PK+ E D+SL +++GDLK L I+ P D++ A +D+ P+ A LKG Sbjct: 1354 SAPKV--EADMSLPSMQGDLKTTDLSIQPPSTDLELQAGQLDVKLPEGPVPEGAGLKGHL 1411 Query: 3279 PKLKMPDMHVNMPKISMPEID-----LNLKGSKLK---GDVDVSGPKLEGDIKAPSLDIK 3330 PKL+MP V + PEID L+LK K++ DV+VS P +E D++AP + Sbjct: 1412 PKLQMPSFKVPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLD 1471 Query: 3331 GPEVDVSGPKLNIEGKSKKSRFKLPKFNFSGSKVQTP------EVDVKGKKPDIDITGPK 3384 G ++ + + +K S+FK+PKF V P VDV K + D++ P Sbjct: 1472 GGRLEEDMSLADKDLTTKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSAPKVEADVSLPS 1531 Query: 3385 V--DINAPDVEVQG-----KVKGSKF--KMPFLSISS--------PKVSMPDVEL---NL 3424 + D+ A D+ +Q +V+ + K+P +S PKV MP ++ +L Sbjct: 1532 MQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVSEGAGLKGHLPKVQMPSFKMPKVDL 1591 Query: 3425 KSPKVKGDLDIAGPNLEGDFKGPKVDIKAPEV--NLNAPDVDVHGP-------------- 3468 K P++ D+ GP L D KGPKV++ AP+V +L++ +VDV P Sbjct: 1592 KGPQI----DVKGPKL--DLKGPKVEVTAPDVKMSLSSMEVDVQAPRAKLDGAQLEGDLS 1645 Query: 3469 ---------DWNLKMPKMKMPKFSVS--GLKAEG---------------PDVAVDLPKGD 3502 D KMPK KMP F VS G E P + DL D Sbjct: 1646 LADKAVTAKDSKFKMPKFKMPSFGVSAPGKSIEASVDVSEPKVEADVSLPSMQGDLKTTD 1705 Query: 3503 INIEGPSMNIE--GPDLNVEGPEG------GLKG-------PKFKMPDMNIKAPKISMPD 3547 ++I+ PS ++E +NV+ PEG G KG P KMP + +K P++ + Sbjct: 1706 LSIQSPSADLEVQAGQVNVKLPEGPLPEGAGFKGHLPKVQMPSLKMPKVALKGPQMDVKG 1765 Query: 3548 IDLNLKGPKVK---GDVDISLPKLEGDLKGPEVDIKGPKV--DINAPDVDVHGPDWHLKM 3602 L+LKGPK + DV++SLP +E D++ P + ++ D++ D DV D KM Sbjct: 1766 PKLDLKGPKAEVMAPDVEVSLPSVEVDVEAPGAKLDSVRLEGDLSLADKDVTAKDSKFKM 1825 Query: 3603 PKVKMPKF------------------------SMPGFKGEGPEVD--VTLPKADIDISGP 3636 PK KMP F S+P +G+ D + LP AD+ + Sbjct: 1826 PKFKMPSFGVSAPGKSIEASVDVSAPKVEAEVSLPSMQGDLKTTDLCIPLPSADLVVQAG 1885 Query: 3637 NVDVDVPD------VNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLNLKGPKMK---G 3687 VD+ +P+ ++G K+ P FKMP++++K P+ + L+LKGPK + Sbjct: 1886 QVDMKLPEGQVPEGAGLKGHLPKVDMPSFKMPKVDLKGPQTDVKGAKLDLKGPKAEVTAP 1945 Query: 3688 DVVVSLPKVEGDLKGPEVDIKGPKV--DIDTPDINIEGSEGKFKGPKFKIPEMHLKAPKI 3745 DV VSLP +E D++ + + G ++ D+ D ++ + KFK PKFK+P + AP Sbjct: 1946 DVEVSLPSMEVDVQAQKAKLDGARLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGR 2005 Query: 3746 SMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPEVDIKGPKVDINAP--DVDVQGPDWHLK 3803 S+ + +++ PKV + DVSLP M+GDLK ++ I+ P D+ VDV+ P+ H+ Sbjct: 2006 SI-EASVDVPAPKV--EADVSLPSMQGDLKTTDLSIQPPSADLKVQTGQVDVKLPEGHVP 2062 Query: 3804 --------MPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGP--- 3852 +PKV+MP MP +GP VD+ PK LD+ PKV++ VPDV + P Sbjct: 2063 EGAGLKGHLPKVEMPSLKMPKVDLKGPQVDIKGPK--LDLKDPKVEMRVPDVEVSLPSME 2120 Query: 3853 -----------------------------EGKLKGPKFKMPEMNIKAPKISMPDIDLNLK 3883 + K K PKFKMP + AP S+ + +++ Sbjct: 2121 VDVQAPRAKLDSAHLQGDLTLANKDLTTKDSKFKMPKFKMPSFGVSAPGKSI-EASVDVS 2179 Query: 3884 GPKVKGDMDVSLPKVEGDMQVPDLDIKGPKVDIN--APDVDVR---GP---DWHLK--MP 3933 PKV+ DM SLP ++GD++ DL I+ D+ A VDV+ GP + LK +P Sbjct: 2180 PPKVEADM--SLPSMQGDLKTTDLSIQPLSADVKVQAGQVDVKLLEGPVPEEVGLKGHLP 2237 Query: 3934 KIKMPKISMPGFKGEGPEVDVNLPKADL-----DVSGPKVDVDVP--DVNIEGPDAKLKG 3986 K++MP +P +GPE+D+ PK DL +V+ P V+V +P +V+++ P AKL G Sbjct: 2238 KLQMPSFKVPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVKAPGAKLDG 2297 Query: 3987 PKFK-----------MPEMNIKAPKISMPDFDLHLKGPKV---------KGDVDVSLPKM 4026 + + + K PK M F + G + K + DVSLP M Sbjct: 2298 ARLEGDMSLADKDVTAKDSKFKMPKFKMLSFGVSALGKSIEASADVSALKVEADVSLPSM 2357 Query: 4027 EGDLKAPEVDIKGPKVDID--APDVDVHGPDWHLK--------MPKVKMPKFSMPGFKGE 4076 +GDLK ++ ++ P D++ A VDV P+ + +PK++MP F MP + Sbjct: 2358 QGDLKTTDLSVQPPSADLEVQAGQVDVKLPEGPVPEGAGLKGHLPKLQMPSFKMPKVDLK 2417 Query: 4077 GPEVDVNLPKADIDVSGPKVDIDTPDI---------DIHGPEGKLKGPKFK--------- 4118 GP++DV PK +D+ GPK D+ PD+ D+ P KL G + Sbjct: 2418 GPQIDVKGPK--LDLKGPKTDVMAPDVEVSQPSVEVDVEAPGAKLDGAWLEGDLSVADKD 2475 Query: 4119 --MPDLHLKAPKISMPEVDLNLKGPKMKGDVDVSLPKVE---------GDLKGPEVDIKG 4167 D K PK MP ++ G ++ VDVS PKVE GDLK ++ I+ Sbjct: 2476 VTTKDSRFKIPKFKMPSFGVSAPGKSIEASVDVSAPKVEADGSLSSMQGDLKATDLSIQP 2535 Query: 4168 PKVDIDVP--DVDVQGPDWHLK--------MPKVKMPKFSMPGFKGEGPDVDVNLPKADL 4217 P D++V VDV+ P+ + +PKV+MP F MP +GP +DV PK L Sbjct: 2536 PSADLEVQAGQVDVKLPEGPVPEGAGLKGHLPKVQMPSFKMPEMDLKGPQLDVKGPK--L 2593 Query: 4218 DVSGPKVDIDVPDV---------NIEGPDAKLKGPKFK-----------MPEMNIKAPKI 4257 D+ GPK ++ PDV +++ P AKL G + + + K PK Sbjct: 2594 DLKGPKAEVTAPDVEMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGVTAKDSKFKMPKF 2653 Query: 4258 SMPDFDLHLKGPKVKGDVDVS---------LPKVEGDLKGPEVDIKGP--KVDIDAPDVD 4306 MP F + G ++ VDVS LP ++GDLK ++ I+ P ++++ A VD Sbjct: 2654 KMPSFRVSAPGESIEALVDVSELKVEADMSLPSMQGDLKTTDISIQPPSAQLEVQAGQVD 2713 Query: 4307 VHGPDWHLK--------MPKVKMPKFSMPGFKGEGPDVDVTLPKADIEISGPKVDIDAPD 4358 V P+ H+ +PK++MP F MP +GP +DV P D++ GPK ++ APD Sbjct: 2714 VKLPEGHVPEGAGLKGHLPKLQMPSFKMPEVDLKGPQIDVKGPNVDLK--GPKAEVTAPD 2771 Query: 4359 VS---------IEGPDAKLKG-----------------------PKFKMPEMNIKAPKIS 4386 V ++ P AKL G PKFKMP + AP S Sbjct: 2772 VKMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGMTAKDSKFKMPKFKMPSFGVSAPGKS 2831 Query: 4387 MPDIDFNLKGPKVKGDVDVSLPKVEGDLKGPEIDIKGPS--LDIDTPDVNIEGPEG---- 4440 I+ ++ ++K + D S P ++GDLK +I I+ PS L++ V+++ PEG Sbjct: 2832 ---IEASVDVSELKVEADGSFPSMQGDLKTTDIRIQPPSAQLEVQAGQVDVKLPEGHVPE 2888 Query: 4441 ---------KLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVK---GDVDVSLPKVE--- 4485 K++ P FKMP++++K P+I + L LKGPK + DV+VSLP VE Sbjct: 2889 GAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAEVTAPDVEVSLPSVEVDV 2948 Query: 4486 -------------SDLKGPEVDIEGPEGKLKGPKFKMPDVHFKSPQISMSDIDLNLKGPK 4532 DL + D+ + K K PKFKMP +P S+ ++ +++ PK Sbjct: 2949 EAPRAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSI-EVSVDVSAPK 3007 Query: 4533 IKGDMDISVPKLEGDLKGPKVDVKGPKVGIDTP--DIDIHGPEG-------------KLK 4577 ++ + +S+P ++GDLK + ++ P ++ +D+ PEG KL+ Sbjct: 3008 VEAE--VSLPSMQGDLKTTDISIEPPSAQLEVQAGQVDLKLPEGHVPEGAGLKGHLPKLQ 3065 Query: 4578 GPKFKMPDLHLKAPKISMPEVDLNLKGPKVKGDMDISLPKVEGDLKGPEVDIRDPKV--- 4634 P FKMP + K P+I + L+LKGPK D++ P VE G EVD+ P Sbjct: 3066 MPSFKMPKVDRKGPQIDVKGPKLDLKGPKT----DVTAPDVEVSQPGMEVDVEAPGAKLD 3121 Query: 4635 ------DIDVPDVDVQGPDWHLKMPKVKMPKF------------------------SMPG 4664 D+ + D DV D KMPK KMP F S+P Sbjct: 3122 GARLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSIEVLVDVSAPKVEADLSLPS 3181 Query: 4665 FKGEGPDVDVNL--PKADIDVSGPKVDVDVPD------VNIEGPDAKLKGPKFKMPEMSI 4716 +G+ + D+++ P A ++V +VDV +P+ ++G KL+ P FKMP++ Sbjct: 3182 MQGDLKNTDISIEPPSAQLEVQAGQVDVKLPEGHVLEGAGLKGHLPKLQMPSFKMPKVDR 3241 Query: 4717 KAPKISMPDIDLNLKGPKVK---GDVDVTLPKVEGDLKGPEADIKGPKV--DINTPDVDV 4771 K P+I + L+LKGPK+ DV+V+ P +E D++ P A + G ++ D++ D DV Sbjct: 3242 KGPQIDIKGPKLDLKGPKMDVTAPDVEVSQPSMEVDVEAPGAKLDGARLEGDLSLADKDV 3301 Query: 4772 HGPDWHLKMPKVKMPKF--SMPGFKGEGPDVDVSLPKADIDVSGP--------------- 4814 D KMPK KMP + S PG K VDVS PKA+ DVS P Sbjct: 3302 TAKDSKFKMPKFKMPSYRASAPG-KSIQASVDVSAPKAEADVSLPSMQGDLKTTDLSIQL 3360 Query: 4815 ----------KVDVDIPD------VNIEGPDAKLKGPKFKMPEINIKAPKISIPDVDLDL 4858 +VDV +P+ ++G K++ P FKMP++++K+P++ I LDL Sbjct: 3361 PSVDLEVQAGQVDVKLPEGHVPEGAGLKGHLPKVEMPSFKMPKVDLKSPQVDIKGPKLDL 3420 Query: 4859 KGPKVK---GDFDVSVPKVEGTLKGPEVDLKGPRL---------DFEGPDAKLSGPSLKM 4906 K PK + D +VS+P VE ++ P L G RL D D+K P KM Sbjct: 3421 KVPKAEVTVPDVEVSLPSVEVDVQAPRAKLDGARLEGDLSLAEKDVTAKDSKFKMPKFKM 3480 Query: 4907 PS-------------LEISAPKVTA--------------------PDVDLHLKAPKIG-- 4931 PS L++SAPKV A P DL ++A ++ Sbjct: 3481 PSFGVSAPGRSIEASLDVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAVQVDVE 3540 Query: 4932 -FSGPKLEGGEVDLKGPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKFGFGAKSPKAD 4990 GP EG + PKVE PSL +P ++++GP + + K PK K PKA+ Sbjct: 3541 LLEGPVPEGAGLKGHLPKVEMPSLK----TPKVDLKGPQIDV---KGPKLDL--KGPKAE 3591 Query: 4991 IKSPSLDVTVPEAELNLETP-----------EISVGGK---GKKSKFKMPKIHMSGPKI- 5035 ++ P ++V++P E++++ P ++S+ K K SKFKMPK M ++ Sbjct: 3592 VRVPDVEVSLPSVEVDVQAPKAKLDAGRLEGDLSLADKDVTAKDSKFKMPKFKMPSFRVS 3651 Query: 5036 ---KAKKQGFDLNVPGGEIDASLKAPD-----VDVNIAGPDAALKV-----DVKSPKTKK 5082 K+ + D++ P E D SL + D++I P A LKV DVK P+ + Sbjct: 3652 APGKSMEASVDVSAPKVEADVSLPSMQGDLKTTDLSIQPPSADLKVQAGQMDVKLPEGQV 3711 Query: 5083 TMFG--KMYFPDVEFDIKSPKFKAEAPLPSPKLEGELQAPDLELSLPAIHVEG--LDIKA 5138 K + P VE +PS K+ P ++L P + ++G LD+K Sbjct: 3712 PEGAGLKEHLPKVE-------------MPSLKM------PKVDLKGPQVDIKGPKLDLKV 3752 Query: 5139 KAPKVKMPDVDISVPKIEGDLKGPK-------VQANLGAPDINIEGLDAKVKTP-----S 5186 +V PDV++S+P +E D++ P+ ++ +L D ++ D+K K P S Sbjct: 3753 SKAEVTAPDVEVSLPSVEVDVQAPRAKLDSAQLEGDLSLADKDVTAKDSKFKMPKFKMPS 3812 Query: 5187 FGISAPQVSIPDVNVNLKGPKIKGDVPSVGLEGP-------------------------- 5220 FG+SAP SI + +V++ PK++ DV ++G Sbjct: 3813 FGVSAPGKSI-EASVHVSAPKVEADVSLPSMQGDLKTTDLSIQPHSADLTVQARQVDMKL 3871 Query: 5221 -------DVDLQGPEAKIKFPKFSMPKIGIPG--------------VKMEGGGAEVHAQL 5259 + L+G K++ P F MPK+ + G K+E +V L Sbjct: 3872 LEGHVPEEAGLKGHLPKVQMPSFKMPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSL 3931 Query: 5260 PSLEGDLRGPDVKLEG----------------PDVSLKGPGVDLPSVNLSMP-------- 5295 PS+E D+ P KL+G D K P +PS +S P Sbjct: 3932 PSVEVDVEAPGAKLDGARLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGKSMEASV 3991 Query: 5296 KVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLSGVGGKMQV--------GGDGVK- 5346 V+ P ++ ++ PS++GDL A+ + V P +L G++ V G +K Sbjct: 3992 DVTAPKVEADVSLPSMQGDLKAT--DLSVQPPSADLEVQAGQVDVKLPEGPVPEGASLKG 4049 Query: 5347 -VPGIDATT----KLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLE------ 5395 +P + + K+++ P + ++GP L D+K PK V APD+ + Sbjct: 4050 HLPKVQMPSFKMPKVDLKGPQIDVKGPKL--------DLKGPKAEVTAPDVKMSLSSMEV 4101 Query: 5396 --------------------------ASEGSIKLPKMKLPQFGISTPGSDL-------HV 5422 A + K+PK K+P FG+S PG + + Sbjct: 4102 DVQAPRAKLDGVQLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSMEASVDVSEL 4161 Query: 5423 NAKG----PQVSGELKGPGVDVNLKGP----RISAPNVDFNL-EGPKVKGSLGATGE--- 5470 AK P + G+LK D++++ P + A VD L EGP KG+ G G Sbjct: 4162 KAKADVSLPSMQGDLK--TTDLSIQSPSADLEVQAGQVDVKLPEGPLPKGA-GLKGHLPK 4218 Query: 5471 -----IKGPTVGGGLPGIGVQGLEGNLQMP--GIKSSGCDVNLPG--VNVKLPTGQISGP 5521 +K P V P + V+G + +L+ P + + +V+LP V+V+ P ++ Sbjct: 4219 VQMPCLKMPKVALKGPQVDVKGPKLDLKGPKADVMTPVVEVSLPSMEVDVEAPGAKLDSV 4278 Query: 5522 EIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDI 5581 ++G L ++ A D K P F M S FG++ G I+ DVS D+ Sbjct: 4279 RLEGDLSLADKDM--TAKDSKFKMPKFKMPS----FGVSAPGKSIEASLDVSALKVEADV 4332 Query: 5582 SLGE-------GHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSG------------P 5622 SL HLS++ + + + L G G P Sbjct: 4333 SLPSMQGDLKTTHLSIQPPSADLEVQAGQEDVKLPEGPVHEGAGLKGHLPKLQMPSFKVP 4392 Query: 5623 KVEGGVKGGQIGLQAPGLSVSGPQGHLESGSGKVTFP----------------------- 5659 KV+ +KG QI + P L + GP+ + S + V+ P Sbjct: 4393 KVD--LKGPQIDVNVPKLDLKGPKVEVTSPNLDVSLPSMEVDIQAPGAKLDSTRLEGDLS 4450 Query: 5660 -----------KMKIPKFTFSGRELVGR----EMGVDVHFPKAEAS-------------- 5690 K K+PKF ++ E+ VDV PK EA Sbjct: 4451 LADKDVTAKDSKFKMPKFKMPSFGMLSPGKSIEVSVDVSAPKMEADMSIPSMQGDLKTTD 4510 Query: 5691 --IQAGAGDGEWEESEVKLK---------------KSKIKMPKFNFSKPKGKGGVTGSPE 5733 IQA + D E + +V LK K++MP F K KG P+ Sbjct: 4511 LRIQAPSADLEVQAGQVDLKLPEGHMPEVAGLKGHLPKVEMPSFKMPKVDLKG-----PQ 4565 Query: 5734 ASISGSKGDLKSSKA---------SLGSLEGEAEAEASSPKGKFSLFKSKKPRHRSNSFS 5784 + G K DLK KA SL S+E + +A S G L H + Sbjct: 4566 VDVKGPKLDLKGPKAEVMAPDVEVSLPSVETDVQAPGSMLDGA-RLEGDLSLAHEDVAGK 4624 Query: 5785 DEREFSGPSTPTGTLEFEGGEVSLEGGKVKG 5815 D + F GP T E+ +VS+ +++G Sbjct: 4625 DSK-FQGPKLSTSGFEWSSKKVSMSSSEIEG 4654 Score = 1107 bits (2863), Expect = 0.0 Identities = 986/3392 (29%), Positives = 1546/3392 (45%), Gaps = 750/3392 (22%) Query: 3064 DVNIEGPEGKLKGPKFKMPEMNIKAPKISMP-------DIDLNLKGP------------- 3103 D E EG+++ PKFK+P + K + D + +G Sbjct: 570 DKGREDTEGQIRMPKFKIPSLGWSPSKHTKTGREKATEDTEQGREGEATATADRREQRRT 629 Query: 3104 ----KVKGDMDVSLPKVEGDMKVPDV-DIKGPKVDINAPDVDVQGPDWHLKMPKIKMPKI 3158 K K D D + K+ + D K K + + +V D KMPK KMP Sbjct: 630 EEGLKDKEDSD----SMTNTTKIQLIHDEKRLKKEQILTEKEVATKDSKFKMPKFKMPLF 685 Query: 3159 --SMPGFKGEGPEVDVNLPKADLDVS--GPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNI 3214 S PG K VDV+ PK + DVS + D+ D++++ P A L+ + ++++ Sbjct: 686 GASAPG-KSMEASVDVSAPKVEADVSLLSMQGDLKTTDLSVQTPSADLE---VQDGQVDV 741 Query: 3215 KAPKISMPDLDLNLKG--PKMKGEVDVSLANVEGDLKGPALDIKGPKIDVDAPDI----- 3267 K P+ +P+ +LKG PK++ SL + DLKGP LD+KGPK +V APD+ Sbjct: 742 KLPEGPLPE-GASLKGHLPKVQRP---SLKMPKVDLKGPKLDLKGPKAEVTAPDVKMSLS 797 Query: 3268 ----DIHGPDAKLKGPKLK-----------MPDMHVNMPKISMPEIDLNLKGSKLKGDVD 3312 D+ P AKL G +L+ D MPK MP ++ G ++ VD Sbjct: 798 SMEVDVQAPRAKLDGARLEGDLSLADKEVTAKDSKFKMPKFKMPSFGVSAPGKSMEDSVD 857 Query: 3313 VSGPKLEGDIKAPSL--DIKGPEVDVSGPKLNIEGKSKKSRFKLPKFNF---SGSKVQTP 3367 VS PK+E D+ S+ D+K ++ + P ++E ++ + KLP+ +G KV P Sbjct: 858 VSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAGQVDVKLPEGPVPEGAGPKVHLP 917 Query: 3368 EVDVKG-KKPDIDITGPKVDINAPDVEVQGKVKGSKFKMPFLSISSP--KVSMPDVELNL 3424 +V++ K P +D+ GP++D+ P ++++G P +++P +VS+P +E+++ Sbjct: 918 KVEMPSFKMPKVDLKGPQIDVKGPKLDLKG---------PKAEVTAPDGEVSLPSMEVDV 968 Query: 3425 KSPKVKGDLDIAGPNLEGDFKGPKVDIKAPEVNLNAPDVDVHGPDWNLKMPKMKMPKFSV 3484 ++ K K D G LEGD L+ D DV D KMPK KMP F V Sbjct: 969 QAQKAKLD----GAWLEGD--------------LSLADKDVTAKDSKFKMPKFKMPSFGV 1010 Query: 3485 SG--------LKAEGPDVAVDLP----KGDINIEGPSMNIEGPDLNVEG----------- 3521 S + P V DL +GD+ S+ DL V+ Sbjct: 1011 SAPGKSIKALVDVSAPKVEADLSLPSMQGDLKTTDLSIQPASTDLKVQADQVDVKLPEGH 1070 Query: 3522 -PEG-GLKG-------PKFKMPDMNIKAPKISMPDIDLNLKGPKVK---GDVDISLPKLE 3569 PEG GLKG P FKMP + +K P++ + L+LK PK + DV++SLP +E Sbjct: 1071 LPEGAGLKGHLPKVEMPSFKMPKVALKGPQVDVKGPKLDLKSPKAEVTAPDVEVSLPSVE 1130 Query: 3570 GDLKGPEVDIKGPKVD--INAPDVDVHGPDWHLKMPKVKMPKF--SMPGFKGEGPEVDVT 3625 D++ P + +++ ++ D DV D KMPK KMP F S PG K VDV+ Sbjct: 1131 VDVEAPGAKLDSARLEGELSLADKDVTAKDSRFKMPKFKMPSFGASAPG-KSIEASVDVS 1189 Query: 3626 LPKADIDISGPNV--DVDVPDVNIEGPDA-----------------------------KL 3654 PK + D+S P++ D+ D++I+ P A K+ Sbjct: 1190 APKVEADVSLPSMQGDLKTTDLSIQPPSADLEVHAGQVDVKLLEGHVPEGAGFKGHLPKV 1249 Query: 3655 KGPKFKMPEMNIKAPKISMPDFDLNLKGPKMK---GDVVVSLPKVEGDLKGPEVDIKGPK 3711 + P KMP++++K P++ + L+LKG K + +V VSLP VE D++ P + G + Sbjct: 1250 QMPSLKMPKVDLKGPQVEVRGPKLDLKGHKAEVTAHEVAVSLPSVEVDMQAPGAKLDGAQ 1309 Query: 3712 VDIDTP--DINIEGSEGKFKGPKFKIPEMHLKAPKISMPDIDLNLKGPKVKGDVDVSLPK 3769 +D D D ++ + KFK PKFK+P + AP S+ + ++L PKV + D+SLP Sbjct: 1310 LDGDLSLADKDVTAKDSKFKMPKFKMPSFGVSAPGKSI-EASVDLSAPKV--EADMSLPS 1366 Query: 3770 MEGDLKGPEVDIKGPKVDIN--APDVDVQGPDWHLK--------MPKVKMPKFSMPGFKG 3819 M+GDLK ++ I+ P D+ A +DV+ P+ + +PK++MP F +P Sbjct: 1367 MQGDLKTTDLSIQPPSTDLELQAGQLDVKLPEGPVPEGAGLKGHLPKLQMPSFKVPKVDL 1426 Query: 3820 EGPDVDVNLPKADL-----DVSGPKVDIDVP--DVNIEGPEGKLKG-------------- 3858 +GP++D+ PK DL +V+ P V++ +P +V++E P KL G Sbjct: 1427 KGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVEAPGAKLDGGRLEEDMSLADKDL 1486 Query: 3859 ---------PKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMQVPDLDI 3909 PKFKMP + AP S+ + +++ PKV+ D VSLP ++GD++ DL I Sbjct: 1487 TTKDSKFKMPKFKMPSFGVSAPGKSI-EASVDVSAPKVEAD--VSLPSMQGDLKATDLSI 1543 Query: 3910 KGPKVD--INAPDVDVRGPDWHLK--------MPKIKMPKISMPGFKGEGPEVDVNLPKA 3959 + P D + A VDV+ P+ + +PK++MP MP +GP++DV PK Sbjct: 1544 QPPSADLEVQAGQVDVKLPEGPVSEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPK- 1602 Query: 3960 DLDVSGPKVDVDVPDV---------NIEGPDAKLKG-----------------------P 3987 LD+ GPKV+V PDV +++ P AKL G P Sbjct: 1603 -LDLKGPKVEVTAPDVKMSLSSMEVDVQAPRAKLDGAQLEGDLSLADKAVTAKDSKFKMP 1661 Query: 3988 KFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKVDID-- 4045 KFKMP + AP S+ + + + PKV + DVSLP M+GDLK ++ I+ P D++ Sbjct: 1662 KFKMPSFGVSAPGKSI-EASVDVSEPKV--EADVSLPSMQGDLKTTDLSIQSPSADLEVQ 1718 Query: 4046 APDVDVHGPDWHLK--------MPKVKMPKFSMPGFKGEGPEVDVNLPKADIDVSGPKVD 4097 A V+V P+ L +PKV+MP MP +GP++DV PK +D+ GPK + Sbjct: 1719 AGQVNVKLPEGPLPEGAGFKGHLPKVQMPSLKMPKVALKGPQMDVKGPK--LDLKGPKAE 1776 Query: 4098 IDTPDIDIHGP--------------------------------EGKLKGPKFKMPDLHLK 4125 + PD+++ P + K K PKFKMP + Sbjct: 1777 VMAPDVEVSLPSVEVDVEAPGAKLDSVRLEGDLSLADKDVTAKDSKFKMPKFKMPSFGVS 1836 Query: 4126 APKISMPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDVP--DVDVQGPD 4183 AP S+ E +++ PK+ + +VSLP ++GDLK ++ I P D+ V VD++ P+ Sbjct: 1837 APGKSI-EASVDVSAPKV--EAEVSLPSMQGDLKTTDLCIPLPSADLVVQAGQVDMKLPE 1893 Query: 4184 WHLK--------MPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEG 4235 + +PKV MP F MP +GP DV A LD+ GPK ++ PDV + Sbjct: 1894 GQVPEGAGLKGHLPKVDMPSFKMPKVDLKGPQTDVK--GAKLDLKGPKAEVTAPDVEVSL 1951 Query: 4236 P--------------------------------DAKLKGPKFKMPEMNIKAPKISMPDFD 4263 P D+K K PKFKMP + AP S+ + Sbjct: 1952 PSMEVDVQAQKAKLDGARLEGDLSLADKDMTAKDSKFKMPKFKMPSFGVSAPGRSI-EAS 2010 Query: 4264 LHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVD--IDAPDVDVHGPDWHLK------ 4315 + + PKV + DVSLP ++GDLK ++ I+ P D + VDV P+ H+ Sbjct: 2011 VDVPAPKV--EADVSLPSMQGDLKTTDLSIQPPSADLKVQTGQVDVKLPEGHVPEGAGLK 2068 Query: 4316 --MPKVKMPKFSMPGFKGEGPDVDVTLPKADIEISGPKVDIDAPDVSIEGP--------- 4364 +PKV+MP MP +GP VD+ PK D++ PKV++ PDV + P Sbjct: 2069 GHLPKVEMPSLKMPKVDLKGPQVDIKGPKLDLK--DPKVEMRVPDVEVSLPSMEVDVQAP 2126 Query: 4365 -----------------------DAKLKGPKFKMPEMNIKAPKISMPDIDFNLKGPKVKG 4401 D+K K PKFKMP + AP S+ + ++ PKV Sbjct: 2127 RAKLDSAHLQGDLTLANKDLTTKDSKFKMPKFKMPSFGVSAPGKSI-EASVDVSPPKV-- 2183 Query: 4402 DVDVSLPKVEGDLKGPEIDIKGPSLDIDTP---------------DVNIEGPEGKLKGPK 4446 + D+SLP ++GDLK ++ I+ S D+ +V ++G KL+ P Sbjct: 2184 EADMSLPSMQGDLKTTDLSIQPLSADVKVQAGQVDVKLLEGPVPEEVGLKGHLPKLQMPS 2243 Query: 4447 FKMPEMNIKAPKISMPDFDLHLKGPKVK---GDVDVSLPKVESDLKGPEVDIEGP--EGK 4501 FK+P++++K P+I + L LK PKV+ DV+VSLP VE D+K P ++G EG Sbjct: 2244 FKVPKVDLKGPEIDIKGPKLDLKDPKVEVTAPDVEVSLPSVEVDVKAPGAKLDGARLEGD 2303 Query: 4502 L---------KGPKFKMPDVHFKSPQISM--SDIDLNLKGPKIKGDMDISVPKLEGDLKG 4550 + K KFKMP S +S I+ + +K + D+S+P ++GDLK Sbjct: 2304 MSLADKDVTAKDSKFKMPKFKMLSFGVSALGKSIEASADVSALKVEADVSLPSMQGDLKT 2363 Query: 4551 PKVDVKGPKVGIDTP--DIDIHGPEG-------------KLKGPKFKMPDLHLKAPKISM 4595 + V+ P ++ +D+ PEG KL+ P FKMP + LK P+I + Sbjct: 2364 TDLSVQPPSADLEVQAGQVDVKLPEGPVPEGAGLKGHLPKLQMPSFKMPKVDLKGPQIDV 2423 Query: 4596 PEVDLNLKGPK---VKGDMDISLPKVEGDLKGP--EVDIRDPKVDIDVPDVDVQGPDWHL 4650 L+LKGPK + D+++S P VE D++ P ++D + D+ V D DV D Sbjct: 2424 KGPKLDLKGPKTDVMAPDVEVSQPSVEVDVEAPGAKLDGAWLEGDLSVADKDVTTKDSRF 2483 Query: 4651 KMPKVKMPKF---------------SMPGFKGEGP-----------DVDVNLPKADIDVS 4684 K+PK KMP F S P + +G D+ + P AD++V Sbjct: 2484 KIPKFKMPSFGVSAPGKSIEASVDVSAPKVEADGSLSSMQGDLKATDLSIQPPSADLEVQ 2543 Query: 4685 GPKVDVDVPD------VNIEGPDAKLKGPKFKMPEMSIKAPKISMPDIDLNLKGPKVK-- 4736 +VDV +P+ ++G K++ P FKMPEM +K P++ + L+LKGPK + Sbjct: 2544 AGQVDVKLPEGPVPEGAGLKGHLPKVQMPSFKMPEMDLKGPQLDVKGPKLDLKGPKAEVT 2603 Query: 4737 -GDVDVTLPKVEGDLKGPEADIKGPKV--DINTPDVDVHGPDWHLKMPKVKMPKF--SMP 4791 DV+++L +E D++ P A + G ++ D++ D V D KMPK KMP F S P Sbjct: 2604 APDVEMSLSSMEVDVQAPRAKLDGARLEGDLSLADKGVTAKDSKFKMPKFKMPSFRVSAP 2663 Query: 4792 GFKGEGPDVDVSLPKADIDVSGPKVDVDIP--DVNIEGPDAKLKGPKFKMPEINIKAPKI 4849 G E VDVS K + D+S P + D+ D++I+ P A+L+ + ++++K P+ Sbjct: 2664 GESIEAL-VDVSELKVEADMSLPSMQGDLKTTDISIQPPSAQLE---VQAGQVDVKLPEG 2719 Query: 4850 SIPDVDLDLKGPKVKGDFDVSVPKVE-GTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPS 4908 +P+ G +KG +PK++ + K PEVDLKGP++D +GP+ L GP + Sbjct: 2720 HVPE------GAGLKGH----LPKLQMPSFKMPEVDLKGPQIDVKGPNVDLKGPKAE--- 2766 Query: 4909 LEISAPKVTAPDVDLHLKAPKIGFSGPKLEGGEVDLKGPKVEAPSLDVHMDSPDINIEGP 4968 VTAPDV + L + ++ P+ + L G ++E D+ + + + Sbjct: 2767 -------VTAPDVKMSLSSMEVDVQAPRAK-----LDGARLEG---DLSLADKGMTAKDS 2811 Query: 4969 DVKIPKFKKPKFGFGAK----------------------SPKADIKSPSLDVTVPEAELN 5006 K+PKFK P FG A S + D+K+ + + P A+L Sbjct: 2812 KFKMPKFKMPSFGVSAPGKSIEASVDVSELKVEADGSFPSMQGDLKTTDIRIQPPSAQLE 2871 Query: 5007 LETPEISV-----------GGKGKKSK-----FKMPKIHMSGPKIKAKKQGFDLNVPGGE 5050 ++ ++ V G KG K FKMPK+ + GP+I K DL P E Sbjct: 2872 VQAGQVDVKLPEGHVPEGAGLKGHLPKVQMPSFKMPKVDLKGPQIDVKGPKLDLKGPKAE 2931 Query: 5051 I---DASLKAPDVDVNIAGPDAALK------------VDV-------KSPKTKKTMFGKM 5088 + D + P V+V++ P A L DV K PK K FG + Sbjct: 2932 VTAPDVEVSLPSVEVDVEAPRAKLDGARLEGDLSLADKDVTAKDSKFKMPKFKMPSFG-V 2990 Query: 5089 YFP----DVEFDIKSPKFKAEAPLPS--------------PKLEGELQAPDLELSLPAIH 5130 P +V D+ +PK +AE LPS P + E+QA ++L LP H Sbjct: 2991 SAPGKSIEVSVDVSAPKVEAEVSLPSMQGDLKTTDISIEPPSAQLEVQAGQVDLKLPEGH 3050 Query: 5131 V-EGLDIKAKAPKVKMPDVDISVPKIEGDLKGPKVQANLGAPDINIEGLDAKVKTPSFGI 5189 V EG +K PK++MP +PK+ D KGP++ P ++++G V P + Sbjct: 3051 VPEGAGLKGHLPKLQMPS--FKMPKV--DRKGPQIDVK--GPKLDLKGPKTDVTAPDVEV 3104 Query: 5190 SAP--QVSIPDVNVNLKGPKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGI--PG 5245 S P +V + L G +++GD L D D+ ++K K PKF MP G+ PG Sbjct: 3105 SQPGMEVDVEAPGAKLDGARLEGD-----LSLADKDVTAKDSKFKMPKFKMPSFGVSAPG 3159 Query: 5246 VKME------GGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPK--- 5296 +E E LPS++GDL+ D+ +E P L+ V V++ +P+ Sbjct: 3160 KSIEVLVDVSAPKVEADLSLPSMQGDLKNTDISIEPPSAQLE---VQAGQVDVKLPEGHV 3216 Query: 5297 VSGPDLDLNL---KGPSLK-GDLDASVPSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDA 5352 + G L +L + PS K +D P + + P L+L G KM V V+V Sbjct: 3217 LEGAGLKGHLPKLQMPSFKMPKVDRKGPQIDIKGPKLDLKGP--KMDVTAPDVEVS--QP 3272 Query: 5353 TTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFG 5412 + +++V AP L G L+GDL+++ D + A + K+PK K+P + Sbjct: 3273 SMEVDVEAPGAKLDGARLEGDLSLA-------------DKDVTAKDSKFKMPKFKMPSYR 3319 Query: 5413 ISTPGSDLH--VNAKGPQVSGELKGPGVDVNLKGPRISA--PNVDFNLEGPKVKGSLGAT 5468 S PG + V+ P+ ++ P + +LK +S P+VD ++ +V L Sbjct: 3320 ASAPGKSIQASVDVSAPKAEADVSLPSMQGDLKTTDLSIQLPSVDLEVQAGQVDVKLPEG 3379 Query: 5469 GEIKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLK 5528 +G + G LP + + + + +KS D+ P +++K+P +++ P+++ L Sbjct: 3380 HVPEGAGLKGHLPKVEMPSFK--MPKVDLKSPQVDIKGPKLDLKVPKAEVTVPDVEVSLP 3437 Query: 5529 GSEVGFHG---------------------AAPDISVKGPAFNMASPESDFGINLKGPKIK 5567 EV A D K P F M S FG++ G I+ Sbjct: 3438 SVEVDVQAPRAKLDGARLEGDLSLAEKDVTAKDSKFKMPKFKMPS----FGVSAPGRSIE 3493 Query: 5568 GGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVS---SALNLDTSKFAG------GLH 5618 DVS D+SL +K + + P A+ +D G GL Sbjct: 3494 ASLDVSAPKVEADVSLSSMQGDLKATDLSIQPPSADLEVQAVQVDVELLEGPVPEGAGLK 3553 Query: 5619 FSGPKVE-GGVKGGQIGLQAPGLSVSGPQGHLESGSGKVTFPKMKIPKFTFSGRELVGRE 5677 PKVE +K ++ L+ P + V GP+ L+ +V P +++ Sbjct: 3554 GHLPKVEMPSLKTPKVDLKGPQIDVKGPKLDLKGPKAEVRVPDVEVSL----------PS 3603 Query: 5678 MGVDVHFPKAEASIQAGAGDGEWEESEVKLKKSKIKMPKFNFSKPKGKGGVTGSPEASIS 5737 + VDV PKA+ GD + +V K SK KMPKF P +S Sbjct: 3604 VEVDVQAPKAKLDAGRLEGDLSLADKDVTAKDSKFKMPKFKM------------PSFRVS 3651 Query: 5738 GSKGDLKSSKASLGSLEGEAEAEASSPKGKFSLFKSKKPRHRSNSFSDEREFSGPSTPTG 5797 KS +AS+ + EA+ S P + L ++ S + P+ Sbjct: 3652 APG---KSMEASVDVSAPKVEADVSLPSMQGDL--------KTTDLSIQ-------PPSA 3693 Query: 5798 TLEFEGGEVSLEGGKVKGKHGKLKFGTFGGLGSKSKGHYEVTGSDDETGKLQGSGVSLAS 5857 L+ + G++ VK G++ G GL + E+ L+G V + Sbjct: 3694 DLKVQAGQMD-----VKLPEGQVPEGA--GL-KEHLPKVEMPSLKMPKVDLKGPQVDIKG 3745 Query: 5858 KKSRLSSSSSNDSGNKVGIQLPEVELSVSTKK 5889 K L S + + V + LP VE+ V + Sbjct: 3746 PKLDLKVSKAEVTAPDVEVSLPSVEVDVQAPR 3777 Score = 34.7 bits (78), Expect = 2.9 Identities = 66/281 (23%), Positives = 104/281 (37%), Gaps = 46/281 (16%) Query: 5623 KVEGGVKGGQIGLQAPGLSVSGPQGHLESGSGKVTFPKMKIPKFTFSGRE--LVGREMGV 5680 + +G G+ GLQ ++ +G E G++ PK KIP +S + GRE Sbjct: 548 EAQGDEGDGEEGLQRTRITEEQDKGR-EDTEGQIRMPKFKIPSLGWSPSKHTKTGREKAT 606 Query: 5681 DVHFPKAEASIQAGAGDGEWEESEVKLKKSK--------IKMPKFNFSKPKGKGGVTGSP 5732 + E A A E +E LK + K+ + K K + Sbjct: 607 EDTEQGREGEATATADRREQRRTEEGLKDKEDSDSMTNTTKIQLIHDEKRLKKEQILTEK 666 Query: 5733 EASISGSKGDLKSSK-----ASLGSLEGEAEAEASSPKGKFSL-FKSKKPRHRSNSFSDE 5786 E + SK + K AS EA + S+PK + + S + ++ S + Sbjct: 667 EVATKDSKFKMPKFKMPLFGASAPGKSMEASVDVSAPKVEADVSLLSMQGDLKTTDLSVQ 726 Query: 5787 REFSGPSTPTGTLEFEGGEVSLEGGKVKGKHGKLKFGTFGGLGSKSKGHYEVTGSDDETG 5846 TP+ LE + G+V VK G L G+ KGH Sbjct: 727 -------TPSADLEVQDGQVD-----VKLPEGPLP------EGASLKGHLP--------- 759 Query: 5847 KLQGSGVSLASKKSRLSSSSSNDSGNKVGIQLPEVELSVST 5887 K+Q SL K L + G K + P+V++S+S+ Sbjct: 760 KVQRP--SLKMPKVDLKGPKLDLKGPKAEVTAPDVKMSLSS 798 >gi|116686120 periaxin isoform 2 [Homo sapiens] Length = 1461 Score = 266 bits (679), Expect = 6e-70 Identities = 399/1556 (25%), Positives = 695/1556 (44%), Gaps = 351/1556 (22%) Query: 2462 LKGPKIK-GDVDV-SVPEVEGKLEVPDMNIRGPKVDVNAPDVQAPDWHLKMPKMKMPKFS 2519 +KGP+ K +++ S+ V+ K VP G D+ DV+ PKFS Sbjct: 117 IKGPRAKVAKLNIQSLSPVKKKKMVP--GALGVPADLAPVDVE----------FSFPKFS 164 Query: 2520 M--PGFKAEGPEVDVNLPKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAP 2577 G KAE + V A + P++ + +V E +L + ++A Sbjct: 165 RLRRGLKAEAVKGPVPAAPARRRLQLPRLRVR--EVAEEAQAARLAAAAPPPRKAKVEAE 222 Query: 2578 KISMPDF---DLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKG------PKVDINAP-DV 2627 + F + L GP++ G +V +P+V P + G P + + AP Sbjct: 223 VAAGARFTAPQVELVGPRLPG-AEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPP 281 Query: 2628 GVQGPDWHLKMPKVKMPKF-SMPGFKG----EGPDGDVKLPKADIDVSGPKVDIEGPDVN 2682 V+ P +++P+V++P S+P E +G V + +DV+ P V G D+ Sbjct: 282 AVEAPAVGIQVPQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTV---GVDLA 338 Query: 2683 IEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVD 2742 + G E + +G + PE+ +K P++S P G + K + + KV PE Sbjct: 339 LPGAEVEARG---EAPEVALKMPRLSFPRF-----GARAKEVAEAKVAKVS-----PEAR 385 Query: 2743 IKGPKVDIDAPDVDVHGPDWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKV 2802 +KGP++ + + + P P++ K+ +P K +P I VSGP+V Sbjct: 386 VKGPRLRMPTFGLSLLEP--RPAAPEVVESKLKLPTIK---------MPSLGIGVSGPEV 434 Query: 2803 DVECPDVNIEGPEGKW-KSPKFKMPEM-HFKTPKISMPDIDLNLTGPKIKGDVDVTGPKV 2860 V +GPE K K+P+ K+P++ P++ +P+++L PK+ ++ PKV Sbjct: 435 KVP------KGPEVKLPKAPEVKLPKVPEAALPEVRLPEVEL----PKVS---EMKLPKV 481 Query: 2861 EG----DLKGPEVDL------KGPKV-DIDVPDVNVQGPDWHLKMPKMKMPKFSMPGFKA 2909 +++ PEV+L K PKV ++ VP+V + LK+ +MK+PK + Sbjct: 482 PEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVRLPEVQL-LKVSEMKLPKVP----EM 536 Query: 2910 EGPEV---DVNLPKADVDVSGPKV-DVEGPDVNIEGPEGKL-KGPKFKMPEMNIKAPKIP 2964 PEV +V LPK ++ P+V +V P+V + PE +L K P+ K+PEM K PK+P Sbjct: 537 AVPEVRLPEVQLPKVS-EMKLPEVSEVAVPEVRL--PEVQLPKVPEMKVPEM--KLPKVP 591 Query: 2965 MPDFDLHLKGPKVKGDVDISLPKVEGDLKGPEVDIRGPQVDIDVPDVGVQGPDWHLKMPK 3024 +K P++K ++ LPKV PE+ + D+ +P+V + K+P+ Sbjct: 592 ------EMKLPEMKLP-EVQLPKV------PEMAVP----DVHLPEVQLP------KVPE 628 Query: 3025 VKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPEGKL-KGPKFKMPE 3083 +K+P+ +P +V LPK ++ VPDV++ PE +L K P+ K+P+ Sbjct: 629 MKLPEMKLP---------EVKLPKVP--------EMAVPDVHL--PEVQLPKVPEMKLPK 669 Query: 3084 M-NIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMKVPDVDIKGPKVDINAPDV-DV 3141 M + P++ +P++ L PKV ++ LPKV +M VPDV + ++ P V ++ Sbjct: 670 MPEMAVPEVRLPEVQL----PKVS---EMKLPKVP-EMAVPDVHLP----EVQLPKVCEM 717 Query: 3142 QGPDWHLKMPKIKMPKISMPGFKGEGPEVDVNLPKADLDVSGPKV-DVDVPDVNI-EGPD 3199 + PD +K+P+IK+PK+ E DV+LP+ L PKV ++ +P++ + + PD Sbjct: 718 KVPD--MKLPEIKLPKVP------EMAVPDVHLPEVQL----PKVSEIRLPEMQVPKVPD 765 Query: 3200 AKL-KGPKFKMP---EMNIKAPKISMPD-LDLNLKGPKMKGEVDVSLANVEGDLKGP--- 3251 L K P+ K+P E+ +KA K + ++ K PKM L E +G Sbjct: 766 VHLPKAPEVKLPRAPEVQLKATKAEQAEGMEFGFKMPKMTMP---KLGRAESPSRGKPGE 822 Query: 3252 -ALDIKGPKIDVDAPDIDIHGPDAKLKGPKLKMPDMHVNMPKISMPEIDLNLKGSK-LKG 3309 ++ G + + ++ G + HV +P +++P ++L+L G+ L+G Sbjct: 823 AGAEVSGKLVTLPCLQPEVDG-------------EAHVGVPSLTLPSVELDLPGALGLQG 869 Query: 3310 DVD---------VSGPKLEGDIK-----APSLDIKGPE---VDVSGPKLN-IEGKSK-KS 3350 V V GP++ ++ PS++I P+ V++ +L IE K K S Sbjct: 870 QVPAAKMGKGERVEGPEVAAGVREVGFRVPSVEIVTPQLPAVEIEEGRLEMIETKVKPSS 929 Query: 3351 RFKLPKFNFSGSKVQTPEVDVKGKKPDIDITG-----PKVDINAPDVEVQGKVKGSKFKM 3405 +F LPKF SG KV E + G+ + ++ PK + A E + K G + Sbjct: 930 KFSLPKFGLSGPKVAKAEAEGAGRATKLKVSKFAISLPKARVGA---EAEAKGAGEAGLL 986 Query: 3406 PFLSISSPKVSMPDVELNLKSPKVKGDLDIAGPNLEGDFKGPKV----------DIKAPE 3455 P L +S P++S+ + +L S KV ++AG +L+ FKGP+ D +A E Sbjct: 987 PALDLSIPQLSL---DAHLPSGKV----EVAGADLK--FKGPRFALPKFGVRGRDTEAAE 1037 Query: 3456 VNLNAPDVDVHGPDWN--LKMPKMKMPKFSVSGLKAEGPDVAVDLPKGDINIEGPSMNIE 3513 + +++ G W+ +KMPK+KMP F ++ Sbjct: 1038 LVPGVAELEGKGWGWDGRVKMPKLKMPSFGLA---------------------------R 1070 Query: 3514 GPDLNVEGPEGGLKGPKFKMPDMNIKAPKISMPDIDLNLKGPKVKGDVDISLPKLEGDLK 3573 G + V+G G K + + +K P++ + + +G + EG + Sbjct: 1071 GKEAEVQGDRAS-PGEKAESTAVQLKIPEVELVTLGAQEEG------------RAEGAVA 1117 Query: 3574 GPEVDIKGPKVDINAPDVDVHGPDWHLKMPK--VKMPKFSMPGFKGE----GPEVDVTLP 3627 + + G KV A V G D L+MP + +P+ + GF GE G + T+P Sbjct: 1118 VSGMQLSGLKVS-TAGQVVTEGHDAGLRMPPLGISLPQVELTGF-GEAGTPGQQAQSTVP 1175 Query: 3628 KADIDISGPNVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP--DFDLNLKGPKM 3685 A+ V VP V + P A++ G + + E K P +++P + D+ L Sbjct: 1176 SAE---GTAGYRVQVPQVTLSLPGAQVAGGELLVGEGVFKMPTVTVPQLELDVGLSREAQ 1232 Query: 3686 KGDVVVSLPKVEGDLKGPEVDIKGPKVDIDTPDINIEGSEGKFKGPKFKIPEMHLKAPKI 3745 G+ EG L+ +K P + + EG+E + G + + + Sbjct: 1233 AGEAATG----EGGLR-----LKLPTLGA-RARVGGEGAEEQPPGAE--------RTFCL 1274 Query: 3746 SMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPEVDIKGPKVD-INAPDVDVQGPDWHLKM 3804 S+PD++L+ P + + + EG+ G ++ ++ P+ + A + +G K Sbjct: 1275 SLPDVELS---PSGGNHAEYQVAEGEGE-AGHKLKVRLPRFGLVRAKEGAEEGE--KAKS 1328 Query: 3805 PKVKMPK--FSMPGF-KGEGPDVDVNLPKADLDVSG--------------PKVDIDVPDV 3847 PK+++P+ FS GEG + + + SG P+V + P Sbjct: 1329 PKLRLPRVGFSQSEMVTGEGSPSPEEEEEEEEEGSGEGASGRRGRVRVRLPRVGLAAPSK 1388 Query: 3848 NIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLK-----GPKVKGDMDVSLPKV 3898 G EG PK + E K+PK P + L+ K G + +G + V LP V Sbjct: 1389 ASRGQEGD-AAPKSPVRE---KSPKFRFPRVSLSPKARSGSGDQEEGGLRVRLPSV 1440 Score = 248 bits (633), Expect = 1e-64 Identities = 395/1534 (25%), Positives = 671/1534 (43%), Gaps = 350/1534 (22%) Query: 800 KLKGPKFKMPEMNIKVPKISMPDVDLHLKGPNVKGEYDVTMPKVESEIKVPDVEL---KS 856 ++KGP+ K+ ++NI+ S+ V P G V +++ DVE K Sbjct: 116 EIKGPRAKVAKLNIQ----SLSPVKKKKMVPGALG--------VPADLAPVDVEFSFPKF 163 Query: 857 AKMDIDVPDVEVQGP------DWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISG 910 +++ + V+GP L++P++++ + + A L A Sbjct: 164 SRLRRGLKAEAVKGPVPAAPARRRLQLPRLRVREVAEEAQAAR-------LAAAAPPPRK 216 Query: 911 PKVGVEVP-DVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGPKVKGEYDMTVP 969 KV EV P+ +L GP+ +P + P++S P + G + + +P Sbjct: 217 AKVEAEVAAGARFTAPQVELVGPR--LPGAEVGVPQVSAPKA---APSAEAAGGFALHLP 271 Query: 970 KLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKF-SMPSLKG----EGPEFDVNLSK 1024 L P V AP V +Q +P++++P S+P+L E E V++ Sbjct: 272 TLGLGAPAPPA-VEAPAVGIQ-------VPQVELPALPSLPTLPTLPCLETREGAVSVVV 323 Query: 1025 ANVDISAPKVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKGPKMKGN 1084 +D++AP V DL+L G E + +G + PE+ + P++S P G + K Sbjct: 324 PTLDVAAPTVGV---DLALPGAEVEARG---EAPEVALKMPRLSFPRF-----GARAKEV 372 Query: 1085 VDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLKGEGP 1144 + K+ P+ ++GP+ ++ P L+ P++ K +P++K Sbjct: 373 AEAKVAKVS-----PEARVKGPR--LRMPTFGLSLLEPRPAAPEVVESKLKLPTIK---- 421 Query: 1145 EVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKL-KGPKFKMPEM-HFKTPKISMPDVDL 1202 +P + VSGP+V + +GPE KL K P+ K+P++ P++ +P+V+L Sbjct: 422 -----MPSLGIGVSGPEVKVP------KGPEVKLPKAPEVKLPKVPEAALPEVRLPEVEL 470 Query: 1203 HLKGPKVKGDVDVSVPKVEGEMKVPDVEIKGPKMDIDAPDV-EVQGPDWHLKMPKMKMPK 1261 PKV ++ +PKV EM VP+V + +++ P V E++ P K+P+M +P+ Sbjct: 471 ----PKVS---EMKLPKVP-EMAVPEVRLP----EVELPKVSEMKLP----KVPEMAVPE 514 Query: 1262 FSMPGFKGEGREVDVNLPKADIDVSGPKV-DVEVPDVSLEGPEGKL-KGPKFKMPEMHFK 1319 +P +V L K ++ PKV ++ VP+V L PE +L K + K+PE+ Sbjct: 515 VRLP---------EVQLLKVS-EMKLPKVPEMAVPEVRL--PEVQLPKVSEMKLPEVSEV 562 Query: 1320 A-PKISMPDVDLNLKGPKLKGDVDVSLPEVEGEMKVPDV---DIKGPKV-DISAPDVDVH 1374 A P++ +P+V L K P++K ++ LP+V EMK+P++ +++ PKV +++ PDV H Sbjct: 563 AVPEVRLPEVQLP-KVPEMKVP-EMKLPKVP-EMKLPEMKLPEVQLPKVPEMAVPDV--H 617 Query: 1375 GPDWHL-KMPKVKMPKFSMPGFKGEGPEVDVKLPKADVDVSGPKMDAEVPDVNIEGPDAK 1433 P+ L K+P++K+P+ +P +VKLPK P+M VPDV++ P+ + Sbjct: 618 LPEVQLPKVPEMKLPEMKLP---------EVKLPKV------PEM--AVPDVHL--PEVQ 658 Query: 1434 L-KGPKFKMPEMSIKPQKISIPDVGLHLKGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKV 1492 L K P+ K+P+M ++++P+V L +V +PKV ++K PKV Sbjct: 659 LPKVPEMKLPKMP----EMAVPEVRLP----------EVQLPKVS--------EMKLPKV 696 Query: 1493 DINAPDVEVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKV-DIDVP 1551 P++ V PD HL P+V++PK E DM LP+ L PKV ++ VP Sbjct: 697 ----PEMAV--PDVHL--PEVQLPKVC------EMKVPDMKLPEIKL----PKVPEMAVP 738 Query: 1552 DVNLEAPEGKL-KGPKFKMPSMNIQTHKISMPDVGLNLKAPKLKTDVDVSLPKVEGDLKG 1610 DV+L PE +L K + ++P M + +PDV L KAP++K LP+ Sbjct: 739 DVHL--PEVQLPKVSEIRLPEMQVP----KVPDVHLP-KAPEVK------LPRA------ 779 Query: 1611 PEIDVKAPKMDVNVGDIDIEGPEGKLKGPKFKMPEM-HFKAPKISMPDVDLHLKGPKVKG 1669 PE+ +KA K + EG E K PK MP++ ++P P G +V G Sbjct: 780 PEVQLKATKAE------QAEGMEFGFKMPKMTMPKLGRAESPSRGKPGE----AGAEVSG 829 Query: 1670 DM---DVSVPKVEGEMKVPDVDIKGPKVDIDAPDVEVHDPDWHLKMPKMKMPKFSMPGFK 1726 + P+V+GE V + P V++D P ++P KM K G + Sbjct: 830 KLVTLPCLQPEVDGEAHVGVPSLTLPSVELDLPGAL----GLQGQVPAAKMGK----GER 881 Query: 1727 AEGPEVDVNLPKADIDVSGPSVDTDAPDLD-IEGPEGKLK--------GSKFKMPKLNIK 1777 EGPEV + + V PSV+ P L +E EG+L+ SKF +PK + Sbjct: 882 VEGPEVAAGVREVGFRV--PSVEIVTPQLPAVEIEEGRLEMIETKVKPSSKFSLPKFGLS 939 Query: 1778 APKVSMPDVDLNLKGPKLK-GEIDASVPELEGDLRGPQVDVKGPFVEAEVPDVDLECP-- 1834 PKV+ + + + KLK + S+P+ G + + KG +P +DL P Sbjct: 940 GPKVAKAEAEGAGRATKLKVSKFAISLPKARV---GAEAEAKGAGEAGLLPALDLSIPQL 996 Query: 1835 ----------------DAKLKGPKFKMPEM----------------------------HF 1850 D K KGP+F +P+ Sbjct: 997 SLDAHLPSGKVEVAGADLKFKGPRFALPKFGVRGRDTEAAELVPGVAELEGKGWGWDGRV 1056 Query: 1851 KAPKISMPDVDLHLKGPKVKGDADVSVPKLEGDLTGPSVGVEVPDVELECPDAKLKGPK- 1909 K PK+ MP L +G + + D + P + + T +V +++P+VEL A+ +G Sbjct: 1057 KMPKLKMPSFGL-ARGKEAEVQGDRASPGEKAEST--AVQLKIPEVELVTLGAQEEGRAE 1113 Query: 1910 --FKMPDMHFKAPKIS---------------MPDVDLHLKGPKVKGDVDVSVPKLEGDLT 1952 + M K+S MP + + L ++ G + P + T Sbjct: 1114 GAVAVSGMQLSGLKVSTAGQVVTEGHDAGLRMPPLGISLPQVELTGFGEAGTPGQQAQST 1173 Query: 1953 GPSVG------VEVPDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVKGD 2006 PS V+VP V L P A++ G + + E FK P +++P ++L + + Sbjct: 1174 VPSAEGTAGYRVQVPQVTLSLPGAQVAGGELLVGEGVFKMPTVTVPQLELDVGLSREAQA 1233 Query: 2007 MDVSVPKVEGEMKVPDVDIKGPKMDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKAEGP 2066 + + + +K+P + G + + + P + +P + Sbjct: 1234 GEAATGEGGLRLKLPTL---GARARVGGEGAEEQPPGAERTFC-LSLPDVELSPSGGNHA 1289 Query: 2067 EVDVNLPKADVVVSGPKVDVEVPDVSL----EGPEG--KLKGPKLKMPEMHFKAPKISMP 2120 E V + + +G K+ V +P L EG E K K PKL++P + F ++ Sbjct: 1290 EYQVAEGEGE---AGHKLKVRLPRFGLVRAKEGAEEGEKAKSPKLRLPRVGFSQSEM--- 1343 Query: 2121 DVDLHLKGPKVKGDVDVSLPKLEGDLTGPS-----VDVEVPDVELECPDAKLKG------ 2169 + G + + EG G S V V +P V L P +G Sbjct: 1344 -----VTGEGSPSPEEEEEEEEEGSGEGASGRRGRVRVRLPRVGLAAPSKASRGQEGDAA 1398 Query: 2170 PKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMD 2203 PK + E K+PK P V+L+ K GD + Sbjct: 1399 PKSPVRE---KSPKFRFPRVSLSPKARSGSGDQE 1429 Score = 240 bits (612), Expect = 3e-62 Identities = 366/1508 (24%), Positives = 659/1508 (43%), Gaps = 316/1508 (20%) Query: 3983 KLKGPKFKMPEMNIKA----PKISMPDFDLHLKGPKVKGDVDVSLPK---MEGDLKAPEV 4035 ++KGP+ K+ ++NI++ K M L + DV+ S PK + LKA V Sbjct: 116 EIKGPRAKVAKLNIQSLSPVKKKKMVPGALGVPADLAPVDVEFSFPKFSRLRRGLKAEAV 175 Query: 4036 DIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVNLPKADIDVS-GP 4094 KGP V L++P++++ + + KA ++ Sbjct: 176 --KGP--------VPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAA 225 Query: 4095 KVDIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKMKGDVDVSLPKV 4154 P +++ GP ++P + P++S P+ + G + LP + Sbjct: 226 GARFTAPQVELVGP---------RLPGAEVGVPQVSAPKA---APSAEAAGGFALHLPTL 273 Query: 4155 EGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPK 4214 P ++ P V I VP V++ +P ++P + V V +P Sbjct: 274 GLGAPAPPA-VEAPAVGIQVPQVELPALPSLPTLP-------TLPCLETREGAVSVVVPT 325 Query: 4215 ADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGD 4274 LDV+ P V +D+ + G + + +G + PE+ +K P++S P F G + K Sbjct: 326 --LDVAAPTVGVDLA---LPGAEVEARG---EAPEVALKMPRLSFPRF-----GARAKEV 372 Query: 4275 VDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGP 4334 + + KV PE +KGP++ + + + P P+V K +P K Sbjct: 373 AEAKVAKVS-----PEARVKGPRLRMPTFGLSLLEP--RPAAPEVVESKLKLPTIK---- 421 Query: 4335 DVDVTLPKADIEISGPKVDIDAPDVSIEGPDAKL-KGPKFKMPEMNIKA-PKISMPDIDF 4392 +P I +SGP+V + +GP+ KL K P+ K+P++ A P++ +P+++ Sbjct: 422 -----MPSLGIGVSGPEVKVP------KGPEVKLPKAPEVKLPKVPEAALPEVRLPEVEL 470 Query: 4393 ----NLKGPKVKGDV--DVSLPKVE----GDLKGPEIDIKGPSLDIDTPDVNIEGPEGKL 4442 +K PKV +V LP+VE ++K P++ ++ P+V + PE +L Sbjct: 471 PKVSEMKLPKVPEMAVPEVRLPEVELPKVSEMKLPKVP------EMAVPEVRL--PEVQL 522 Query: 4443 -KGPKFKMPEM-NIKAPKISMPDFDL----HLKGPKVKGDV-------DVSLPKVESDLK 4489 K + K+P++ + P++ +P+ L +K P+V +V LPKV ++K Sbjct: 523 LKVSEMKLPKVPEMAVPEVRLPEVQLPKVSEMKLPEVSEVAVPEVRLPEVQLPKVP-EMK 581 Query: 4490 GPEVDI-EGPEGKLKGPKFKMPDVHF-KSPQISMSDIDL-NLKGPKIKGDMDISVPKLE- 4545 PE+ + + PE KL P+ K+P+V K P++++ D+ L ++ PK+ ++ +P+++ Sbjct: 582 VPEMKLPKVPEMKL--PEMKLPEVQLPKVPEMAVPDVHLPEVQLPKVP---EMKLPEMKL 636 Query: 4546 GDLKGPKVDVKGPKVGIDTPDIDIHGPEGKL-KGPKFKMPDL-HLKAPKISMPEVDLNLK 4603 ++K PKV P++ + D+H PE +L K P+ K+P + + P++ +PEV L Sbjct: 637 PEVKLPKV----PEMAVP----DVHLPEVQLPKVPEMKLPKMPEMAVPEVRLPEVQL--- 685 Query: 4604 GPKVKGDMDISLPKVEG----DLKGPEVDIRDPKV-DIDVPDVDVQGPDWHLKMPKVKMP 4658 PKV ++ LPKV D+ PEV + PKV ++ VPD +K+P++K+P Sbjct: 686 -PKVS---EMKLPKVPEMAVPDVHLPEVQL--PKVCEMKVPD---------MKLPEIKLP 730 Query: 4659 KFSMPGFKGEGPDV---DVNLPKADIDVSGPKVDVD-VPDVNI---------EGPDAKLK 4705 K PDV +V LPK ++ P++ V VPDV++ P+ +LK Sbjct: 731 KVPEMAV----PDVHLPEVQLPKVS-EIRLPEMQVPKVPDVHLPKAPEVKLPRAPEVQLK 785 Query: 4706 GPKFKMPE---MSIKAPKISMPDIDL---------NLKGPKVKGDVDVTLPKVEGDLKGP 4753 K + E K PK++MP + G +V G + VTLP ++ ++ G Sbjct: 786 ATKAEQAEGMEFGFKMPKMTMPKLGRAESPSRGKPGEAGAEVSGKL-VTLPCLQPEVDG- 843 Query: 4754 EADIKGPKVDINTPDVDVHGP-DWHLKMPKVKMPKFSMPGFKGEGPDV-----DVSLPKA 4807 EA + P + + + ++D+ G ++P KM K G + EGP+V +V Sbjct: 844 EAHVGVPSLTLPSVELDLPGALGLQGQVPAAKMGK----GERVEGPEVAAGVREVGFRVP 899 Query: 4808 DIDVSGPKVD-VDIPDVNIEGPDAKLK-GPKFKMPEINIKAPKISIPDVDLDLKGPKVK- 4864 +++ P++ V+I + +E + K+K KF +P+ + PK++ + + + K+K Sbjct: 900 SVEIVTPQLPAVEIEEGRLEMIETKVKPSSKFSLPKFGLSGPKVAKAEAEGAGRATKLKV 959 Query: 4865 GDFDVSVPKVEGTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLH 4924 F +S+PK G E + KG +G + +P+L++S P+++ +D H Sbjct: 960 SKFAISLPKAR---VGAEAEAKG------------AGEAGLLPALDLSIPQLS---LDAH 1001 Query: 4925 LKAPKIGFSGPKLEGGEVDLKGPKVEAPSLDVHMDSPDI--------NIEGPD------V 4970 L + K+ ++ G ++ KGP+ P V + +EG V Sbjct: 1002 LPSGKV-----EVAGADLKFKGPRFALPKFGVRGRDTEAAELVPGVAELEGKGWGWDGRV 1056 Query: 4971 KIPKFKKPKFGFGAKSPKADIKSP--SLDVTVPEAELNLETPEISVGGKGKKSKFKMP-K 5027 K+PK K P FG A+ +A+++ S + L+ PE+ + G + + + Sbjct: 1057 KMPKLKMPSFGL-ARGKEAEVQGDRASPGEKAESTAVQLKIPEVELVTLGAQEEGRAEGA 1115 Query: 5028 IHMSGPKIKAKKQGFDLNVPGGEIDASLKAPDVDVNIAGPDAALKVDVKSPKTKKTMFGK 5087 + +SG ++ K V DA L+ P + +++ P+ + T FG Sbjct: 1116 VAVSGMQLSGLKVSTAGQVVTEGHDAGLRMPPLGISL-------------PQVELTGFG- 1161 Query: 5088 MYFPDVEFDIKSPKFKAEAPLPSPKLEG--ELQAPDLELSLPAIHVEGLDIKAKAPKVKM 5145 + +P +A++ +PS + +Q P + LSLP V G ++ KM Sbjct: 1162 --------EAGTPGQQAQSTVPSAEGTAGYRVQVPQVTLSLPGAQVAGGELLVGEGVFKM 1213 Query: 5146 PDVDISVPKIEGDLKGPKVQANLGAPDINIEGLDAKVKTPSFGISAPQ------------ 5193 P V +VP++E D+ G +A G GL ++K P+ G A Sbjct: 1214 PTV--TVPQLELDV-GLSREAQAGEAATGEGGL--RLKLPTLGARARVGGEGAEEQPPGA 1268 Query: 5194 -----VSIPDVNVNLKGP----------------KIKGDVPSVGLEGPDVDLQGPEAKIK 5232 +S+PDV ++ G K+K +P GL + E K K Sbjct: 1269 ERTFCLSLPDVELSPSGGNHAEYQVAEGEGEAGHKLKVRLPRFGLVRAKEGAEEGE-KAK 1327 Query: 5233 FPKFSMPKIGIPGVKM---EGGGAEVHAQLPSLEGDLRG------------PDVKLEGPD 5277 PK +P++G +M EG + + EG G P V L P Sbjct: 1328 SPKLRLPRVGFSQSEMVTGEGSPSPEEEEEEEEEGSGEGASGRRGRVRVRLPRVGLAAPS 1387 Query: 5278 VSLKGPGVDLPS---VNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLSGV 5334 + +G D V PK P + L+ K S GD + +++ + G + +G Sbjct: 1388 KASRGQEGDAAPKSPVREKSPKFRFPRVSLSPKARSGSGDQEEGGLRVRLPSVGFSETGA 1447 Query: 5335 GGKMQVGG 5342 G ++ G Sbjct: 1448 PGPARMEG 1455 Score = 239 bits (609), Expect = 8e-62 Identities = 404/1538 (26%), Positives = 672/1538 (43%), Gaps = 347/1538 (22%) Query: 2317 VDFNLKGPKIKGDVDVSAPKLEG-ELKGPELDVKGPKLDADMPEVAVEGPNGKWKTPKFK 2375 V F LK GD+ + + G E+KGP V + + P + G P Sbjct: 92 VSFCLKRTVPTGDLALRPGTVSGYEIKGPRAKVAKLNIQSLSPVKKKKMVPGALGVPADL 151 Query: 2376 MP-DMHFKAPKISMPDLDLHLKSPKAKGEVD-------VDVPKLE-----GDLKGPHVDV 2422 P D+ F PK S L LK+ KG V + +P+L + + + Sbjct: 152 APVDVEFSFPKFSR--LRRGLKAEAVKGPVPAAPARRRLQLPRLRVREVAEEAQAARLAA 209 Query: 2423 SGPDIDIEGPEGKLKGPKFKMPDMHFKAPNISMPDVDLNLKGPKIKGDVDVSVPEVEGKL 2482 + P P K K F AP + L GP++ G +V VP+V Sbjct: 210 AAP------PPRKAKVEAEVAAGARFTAPQVE-------LVGPRLPG-AEVGVPQVSAPK 255 Query: 2483 EVPDMNIRG------PKVDVNAPD---VQAPDWHLKMPKMKMPKF-SMPGFKA------- 2525 P G P + + AP V+AP +++P++++P S+P Sbjct: 256 AAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVGIQVPQVELPALPSLPTLPTLPCLETR 315 Query: 2526 EG------PEVDVNLPKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMP--------- 2570 EG P +DV P VD++ P ++E E PE LK P+L P Sbjct: 316 EGAVSVVVPTLDVAAPTVGVDLALPGAEVEARG---EAPEVALKMPRLSFPRFGARAKEV 372 Query: 2571 ----------EMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKV 2620 E +K P++ MP F L L P+ + VE LK P + + + Sbjct: 373 AEAKVAKVSPEARVKGPRLRMPTFGLSLLEPR-----PAAPEVVESKLKLPTIKMPSLGI 427 Query: 2621 DINAPDVGV-QGPDWHL-KMPKVKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPKVDIEG 2678 ++ P+V V +GP+ L K P+VK+PK E +V+LP+ ++ PKV Sbjct: 428 GVSGPEVKVPKGPEVKLPKAPEVKLPKVP------EAALPEVRLPEVEL----PKV---- 473 Query: 2679 PDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVE----G 2734 ++K P K+PEM + P++ +P+++L PKV ++ LPKV Sbjct: 474 ---------SEMKLP--KVPEMAV--PEVRLPEVEL----PKVS---EMKLPKVPEMAVP 513 Query: 2735 DLKGPEV------DIKGPKV-DIDAPDVDVHGPDWHLKMPKIKMPKISMPGFKGEGPDV- 2786 +++ PEV ++K PKV ++ P+V ++P++++PK+S + + P+V Sbjct: 514 EVRLPEVQLLKVSEMKLPKVPEMAVPEV---------RLPEVQLPKVS----EMKLPEVS 560 Query: 2787 DVNLPKADI-DVSGPKV-DVECPDVNI-EGPEGKWKSPKFKMPEMHF-KTPKISMPDIDL 2842 +V +P+ + +V PKV +++ P++ + + PE K P+ K+PE+ K P++++PD+ L Sbjct: 561 EVAVPEVRLPEVQLPKVPEMKVPEMKLPKVPE--MKLPEMKLPEVQLPKVPEMAVPDVHL 618 Query: 2843 NLTGPKIKGDVDVTGPKVEGDLKGPEV---DLKGPKV-DIDVPDVNVQGPDWHL-KMPKM 2897 +V PKV ++K PE+ ++K PKV ++ VPDV++ P+ L K+P+M Sbjct: 619 ----------PEVQLPKVP-EMKLPEMKLPEVKLPKVPEMAVPDVHL--PEVQLPKVPEM 665 Query: 2898 KMPKFSMPGFKAEGPEV---DVNLPKADVDVSGPKV-DVEGPDVNIEGPEGKL------K 2947 K+PK MP PEV +V LPK ++ PKV ++ PDV++ PE +L K Sbjct: 666 KLPK--MPEMAV--PEVRLPEVQLPKVS-EMKLPKVPEMAVPDVHL--PEVQLPKVCEMK 718 Query: 2948 GPKFKMPEMNIKAPKIP-MPDFDLHLKGPKVKGDVDISLPKVEGDLKGPEVDIRGPQVDI 3006 P K+PE IK PK+P M D+HL ++ LPKV +IR P ++ Sbjct: 719 VPDMKLPE--IKLPKVPEMAVPDVHLP--------EVQLPKVS--------EIRLP--EM 758 Query: 3007 DVPDVGVQGPDWHL-KMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDV 3065 VP V PD HL K P+VK+P+ P+V + KA+ Sbjct: 759 QVPKV----PDVHLPKAPEVKLPR---------APEVQLKATKAE--------------- 790 Query: 3066 NIEGPEGKLKGPKFKMPEM-NIKAPKISMPDIDLNLKGPKVKGDMDVSL----PKVEGDM 3120 EG E K PK MP++ ++P P G +V G + V+L P+V+G+ Sbjct: 791 QAEGMEFGFKMPKMTMPKLGRAESPSRGKP----GEAGAEVSGKL-VTLPCLQPEVDGEA 845 Query: 3121 KVPDVDIKGPKVDINAPD-VDVQGPDWHLKMPKIKMPKISMPGFKGEGPEV-----DVNL 3174 V + P V+++ P + +QG ++P KM K G + EGPEV +V Sbjct: 846 HVGVPSLTLPSVELDLPGALGLQG-----QVPAAKMGK----GERVEGPEVAAGVREVGF 896 Query: 3175 PKADLDVSGPKVD-VDVPDVNIEGPDAKLK-GPKFKMPEMNIKAPKISMPDLD-----LN 3227 +++ P++ V++ + +E + K+K KF +P+ + PK++ + + Sbjct: 897 RVPSVEIVTPQLPAVEIEEGRLEMIETKVKPSSKFSLPKFGLSGPKVAKAEAEGAGRATK 956 Query: 3228 LKGPKMKGEVDVSLANVEGDLKG-------PALDIKGPKIDVDA----PDIDIHGPDAKL 3276 LK K + + E + KG PALD+ P++ +DA +++ G D K Sbjct: 957 LKVSKFAISLPKARVGAEAEAKGAGEAGLLPALDLSIPQLSLDAHLPSGKVEVAGADLKF 1016 Query: 3277 KGPKLKMPDMHVNMPKISMPEI---DLNLKGSKLKGDVDVSGPKLEGDIKAPSLDI-KGP 3332 KGP+ +P V E+ L+G D V PKL K PS + +G Sbjct: 1017 KGPRFALPKFGVRGRDTEAAELVPGVAELEGKGWGWDGRVKMPKL----KMPSFGLARGK 1072 Query: 3333 EVDVSGPKLNIEGKSKKS--RFKLPKFNFSGSKVQTP-----EVDVKGKKPDIDITGPKV 3385 E +V G + + K++ + + K+P+ Q V V G + ++G KV Sbjct: 1073 EAEVQGDRASPGEKAESTAVQLKIPEVELVTLGAQEEGRAEGAVAVSG----MQLSGLKV 1128 Query: 3386 DINAPDVEVQGKVKGSKFKMPFLSISSPKVSMPDV-ELNLKSPKVKGDLDIAGPNLEGDF 3444 A V +G G +MP L IS P+V + E + + + P+ EG Sbjct: 1129 S-TAGQVVTEGHDAG--LRMPPLGISLPQVELTGFGEAGTPGQQAQSTV----PSAEGT- 1180 Query: 3445 KGPKVDIKAPEVNLNAPDVDVHGPDWNLKMPKMKMPKFSVSGLKAEGPDVAVDLPKGDIN 3504 G +V + P+V L+ P V G + + KMP +V L+ + ++ + G+ Sbjct: 1181 AGYRVQV--PQVTLSLPGAQVAGGELLVGEGVFKMPTVTVPQLELD-VGLSREAQAGEAA 1237 Query: 3505 IEGPSMNIEGPDLNVEGPEGGLKGPKFKMPDMNIKAPKISMPDIDLNLKGPKVKGDVDIS 3564 + ++ P L GG +G + + P + +S+PD++L+ P + Sbjct: 1238 TGEGGLRLKLPTLGARARVGG-EGAEEQPPGAE-RTFCLSLPDVELS---PSGGNHAEYQ 1292 Query: 3565 LPKLEGDLKGPEVDIKGPKVDINAPDVDVHGPDWHLKMPKVKMPKFSMP--GFK------ 3616 + + EG+ G ++ ++ P+ + V + + K K PK +P GF Sbjct: 1293 VAEGEGE-AGHKLKVRLPRFGL------VRAKEGAEEGEKAKSPKLRLPRVGFSQSEMVT 1345 Query: 3617 GEGPEVDVTLPKADIDISGP-------NVDVDVPDVNIEGPDAKLKG------PKFKMPE 3663 GEG + + + SG V V +P V + P +G PK + E Sbjct: 1346 GEGSPSPEEEEEEEEEGSGEGASGRRGRVRVRLPRVGLAAPSKASRGQEGDAAPKSPVRE 1405 Query: 3664 MNIKAPKISMPDFDLNLK-----GPKMKGDVVVSLPKV 3696 K+PK P L+ K G + +G + V LP V Sbjct: 1406 ---KSPKFRFPRVSLSPKARSGSGDQEEGGLRVRLPSV 1440 Score = 236 bits (603), Expect = 4e-61 Identities = 385/1596 (24%), Positives = 695/1596 (43%), Gaps = 283/1596 (17%) Query: 9 ELLLPNWQGSGSHGLTIAQRD-DGVFVQEVTQNSPAARTGVVKEGDQIVGATIYFDNLQS 67 E+++ +G G+ +A +G+FV+E+ ++SPAAR+ ++EGDQ++ A ++F+N + Sbjct: 18 EIIVETEAQTGVSGINVAGGGKEGIFVRELREDSPAARSLSLQEGDQLLSARVFFENFKY 77 Query: 68 GEVTQLLNTMGHHTVGLKLHR---KGDRSPEPGQTWTREVFSSCSSEVVLSGDDEEYQRI 124 + +LL + V L R GD + PG E+ + L+ Q + Sbjct: 78 EDALRLLQCAEPYKVSFCLKRTVPTGDLALRPGTVSGYEIKGPRAKVAKLN-----IQSL 132 Query: 125 YTTKIKPRLKSEDGVEGDLGETQSRTITVTRRVTAYTVDVTGREGAKDIDISSP------ 178 K K + GV DL ++ R G K + P Sbjct: 133 SPVKKKKMVPGALGVPADLAPVDVE--------FSFPKFSRLRRGLKAEAVKGPVPAAPA 184 Query: 179 EFKIKIPRHELTEISNVDVETQSGKTVIRLPSGSGAASPTGSAVDIR--AGAISASGPEL 236 ++++PR + E++ E Q+ + P A A R A + GP L Sbjct: 185 RRRLQLPRLRVREVAE---EAQAARLAAAAPPPRKAKVEAEVAAGARFTAPQVELVGPRL 241 Query: 237 QGAGHSKLQVTMPGIKVGGSGVNVNAKGLDLGGRGGVQVPAVDISSSLGGRAVEVQGPSL 296 GA QV+ P A L G G PAV+ + ++G + +V+ P+L Sbjct: 242 PGAEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPPAVE-APAVGIQVPQVELPAL 300 Query: 297 ESGDHGKIKFPTMKVPKFGVSTGREG-----------QTPKAGLRVSAPEVSVGHKGGKP 345 S PT+ P REG P G+ ++ P V +G P Sbjct: 301 PS-------LPTL--PTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEARGEAP 351 Query: 346 GLTIQAPQL----------EVSVPSANIEGLEGKLKGPQITGPSLEGDLGLKGAKPQGHI 395 + ++ P+L EV+ E ++KGP++ P+ GL +P+ Sbjct: 352 EVALKMPRLSFPRFGARAKEVAEAKVAKVSPEARVKGPRLRMPT----FGLSLLEPR--- 404 Query: 396 GVDASAPQIGGSITGPSVEVQAPDIDVQGPGSKLNVPKMKVPKFSVSGAKGEETGIDVTL 455 +AP++ S +++ P I + G ++ P++KVPK G +V L Sbjct: 405 ---PAAPEVVES------KLKLPTIKMPSLGIGVSGPEVKVPK-----------GPEVKL 444 Query: 456 PTG-EVTVPGVSGDVSLPEIATGGLE-GKMKGTKV-KTPEMIIQKPKISMQDVDL-SLGS 511 P EV +P V + +LPE+ +E K+ K+ K PEM + P++ + +V+L + Sbjct: 445 PKAPEVKLPKVP-EAALPEVRLPEVELPKVSEMKLPKVPEMAV--PEVRLPEVELPKVSE 501 Query: 512 PKLKGDIKVSAPGVQGDVKGPQVALKGSRVDIETPNLEGTLTGPRLGSPSGKTGTCRISM 571 KL +++ P +V+ P+V L +++ P + P + P + + Sbjct: 502 MKLPKVPEMAVP----EVRLPEVQLL-KVSEMKLPKV------PEMAVP-------EVRL 543 Query: 572 SEVDLNVAAPKVKGGVDVTLPRVEGKVKVPEV---DVRGPKV-DVSAPDVE-AHGPEWNL 626 EV L PKV ++ LP V +V VPEV +V+ PKV ++ P+++ PE + Sbjct: 544 PEVQL----PKVS---EMKLPEV-SEVAVPEVRLPEVQLPKVPEMKVPEMKLPKVPE--M 593 Query: 627 KMPKMKMPTFSTPGAKGEG-PDVHMTLPKGDISISGPKVNVEAPDVNLEGLGGKLKGPDV 685 K+P+MK+P P PDVH+ + PKV P++ L ++K P+V Sbjct: 594 KLPEMKLPEVQLPKVPEMAVPDVHLP------EVQLPKV----PEMKLP----EMKLPEV 639 Query: 686 KLPDMSVKTPKISMPDVDLHVKGTKVKGEYDVTVPKLEGELKGPKV-DIDAPDVDVHGPD 744 KLP K P++++PDV L +V +PK+ E+K PK+ ++ P+V + P+ Sbjct: 640 KLP----KVPEMAVPDVHLP----------EVQLPKVP-EMKLPKMPEMAVPEVRL--PE 682 Query: 745 WHL-KMPKMKMPKFSVPGFKAEGPEVDVNLPKADVDISGPKI-DVTAPDVSIEEPEGKL- 801 L K+ +MK+PK VP E DV+LP+ + PK+ ++ PD+ + PE KL Sbjct: 683 VQLPKVSEMKLPK--VP----EMAVPDVHLPEVQL----PKVCEMKVPDMKL--PEIKLP 730 Query: 802 KGPKFKMPEMNIKVPKISMPDV-DLHLKGPNVKGEYDVTMPKVESEIKV---PDVELKSA 857 K P+ +P++++ P++ +P V ++ L V DV +PK E+K+ P+V+LK+ Sbjct: 731 KVPEMAVPDVHL--PEVQLPKVSEIRLPEMQVPKVPDVHLPKA-PEVKLPRAPEVQLKAT 787 Query: 858 KMDIDVPDVEVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVGVEV 917 K + + +G ++ KMPKM MPK +AE P +A ++SG V + Sbjct: 788 KAE------QAEGMEFGFKMPKMTMPKLG----RAESPSRG-KPGEAGAEVSGKLVTLPC 836 Query: 918 PDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGP-KVKGEYDMTVPKLEGDLK 976 ++G E ++ P +++P V+L + G ++G+ ++ Sbjct: 837 LQPEVDG-------------EAHVGVPSLTLPSVELDLPGALGLQGQVPAAKMGKGERVE 883 Query: 977 GPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGPEFDVNLSKANVDISAPKVDT 1036 GP+V +V + P + P ++P + + E E V K + S PK Sbjct: 884 GPEVAAGVREVGFRVPSVEIVTP--QLPAVEIEEGRLEMIETKV---KPSSKFSLPKFGL 938 Query: 1037 NAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKGPKMKG---NVDISAPKIE 1093 + P ++ EG + K K+ + PK + + + KG G +D+S P++ Sbjct: 939 SGPKVAKAEAEGAGRATKLKVSKFAISLPKARV-GAEAEAKGAGEAGLLPALDLSIPQLS 997 Query: 1094 GEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLKGEGPEVDVNLPKA 1153 + +P + VE G D K P+ +PKF + E E+ + + Sbjct: 998 LDAHLP------------SGKVEVAGADLKFKGPRFALPKFGVRGRDTEAAELVPGVAEL 1045 Query: 1154 DVVVSGPKVDIEAPDVSL------EGPEGKLKGPKFKMPEMHFKTP-KISMPDVDLHLKG 1206 + G ++ P + + G E +++G + E T ++ +P+V+L G Sbjct: 1046 EGKGWGWDGRVKMPKLKMPSFGLARGKEAEVQGDRASPGEKAESTAVQLKIPEVELVTLG 1105 Query: 1207 PKVKGDVDVSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMPKM--KMPKFSM 1264 + +G + EG + V +++ G K+ A V +G D L+MP + +P+ + Sbjct: 1106 AQEEG-------RAEGAVAVSGMQLSGLKVS-TAGQVVTEGHDAGLRMPPLGISLPQVEL 1157 Query: 1265 PGFKGE----GREVDVNLPKADIDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKA 1320 GF GE G++ +P A+ +G + V+VP V+L P ++ G + + E FK Sbjct: 1158 TGF-GEAGTPGQQAQSTVPSAE-GTAGYR--VQVPQVTLSLPGAQVAGGELLVGEGVFKM 1213 Query: 1321 PKISMPDVDLNLKGPKLKGDVDVSLPEVEGEMKVPDVDIKGPKVDISAPDVDVHGP---- 1376 P +++P ++L++ + + + E +K+P + G + + + P Sbjct: 1214 PTVTVPQLELDVGLSREAQAGEAATGEGGLRLKLPTL---GARARVGGEGAEEQPPGAER 1270 Query: 1377 DWHLKMPKVKM-------PKFSMPGFKGE-GPEVDVKLPKADVDVSGPKMDAEVPDVNIE 1428 + L +P V++ ++ + +GE G ++ V+LP+ + K AE E Sbjct: 1271 TFCLSLPDVELSPSGGNHAEYQVAEGEGEAGHKLKVRLPR--FGLVRAKEGAE------E 1322 Query: 1429 GPDAKLKGPKFKMPEMSIKPQKISIPDVGLHLKGPKMKGDYDVTVPKVEGEIKAPDVDIK 1488 G K K PK ++P + ++ G P+ + + + + V ++ Sbjct: 1323 G--EKAKSPKLRLPRVGFSQSEMV---TGEGSPSPEEEEEEEEEGSGEGASGRRGRVRVR 1377 Query: 1489 GPKVDINAPDVEVHGP--DWHLKMP-KVKMPKFSMP 1521 P+V + AP G D K P + K PKF P Sbjct: 1378 LPRVGLAAPSKASRGQEGDAAPKSPVREKSPKFRFP 1413 Score = 235 bits (600), Expect = 9e-61 Identities = 377/1468 (25%), Positives = 654/1468 (44%), Gaps = 302/1468 (20%) Query: 1075 DLKGPKMKG---NVDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKM 1131 ++KGP+ K N+ +P ++ + VP G D+ DVE Sbjct: 116 EIKGPRAKVAKLNIQSLSP-VKKKKMVPGA--LGVPADLAPVDVE------------FSF 160 Query: 1132 PKFSM--PSLKGEGPEVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGP-----KFK 1184 PKFS LK E + V A + P++ + +V+ E +L K K Sbjct: 161 PKFSRLRRGLKAEAVKGPVPAAPARRRLQLPRLRVR--EVAEEAQAARLAAAAPPPRKAK 218 Query: 1185 MPEMHFKTPKISMPDVDLHLKGPKVKGDVDVSVPKVEGEMKVPDVEIKG------PKMDI 1238 + + + P V+L GP++ G +V VP+V P E G P + + Sbjct: 219 VEAEVAAGARFTAPQVEL--VGPRLPG-AEVGVPQVSAPKAAPSAEAAGGFALHLPTLGL 275 Query: 1239 DAP-DVEVQGPDWHLKMPKMKMPKF-SMPGFKG----EGREVDVNLPKADIDVSGPKVDV 1292 AP V+ P +++P++++P S+P E RE V++ +DV+ P V V Sbjct: 276 GAPAPPAVEAPAVGIQVPQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGV 335 Query: 1293 EVPDVSLEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLNLKGPKLKGDVDVSLPEVEGEM 1352 D++L G E + +G + PE+ K P++S P G + K + + +V E Sbjct: 336 ---DLALPGAEVEARG---EAPEVALKMPRLSFPRF-----GARAKEVAEAKVAKVSPEA 384 Query: 1353 KVPDVDIKGPKVDISAPDVDVHGPDW---HLKMPKVKMPKFSMPGFKGEGPEV------D 1403 +V ++ P +S + P+ LK+P +KMP G GPEV + Sbjct: 385 RVKGPRLRMPTFGLSLLEPRPAAPEVVESKLKLPTIKMPSL---GIGVSGPEVKVPKGPE 441 Query: 1404 VKLPKADVDVSGPKM-DAEVPDVNIEGPDAKLKGPKF------KMPEMSIKPQKISIPDV 1456 VKLPKA +V PK+ +A +P+V + P+ +L PK K+PEM++ ++ +P+V Sbjct: 442 VKLPKAP-EVKLPKVPEAALPEVRL--PEVEL--PKVSEMKLPKVPEMAVP--EVRLPEV 494 Query: 1457 GLHLKGPKMKGDYDVTVPKVEG----EIKAPDV------DIKGPKVDINAPDVEVHGPDW 1506 L PK+ ++ +PKV E++ P+V ++K PKV P++ V Sbjct: 495 EL----PKVS---EMKLPKVPEMAVPEVRLPEVQLLKVSEMKLPKV----PEMAVP---- 539 Query: 1507 HLKMPKVKMPKFSMPGFKGEGPEV------DMNLPKADLGVSGPKV-DIDVPDVNL-EAP 1558 +++P+V++PK S + + PEV ++ LP+ L PKV ++ VP++ L + P Sbjct: 540 EVRLPEVQLPKVS----EMKLPEVSEVAVPEVRLPEVQL----PKVPEMKVPEMKLPKVP 591 Query: 1559 EGKLKGPKFKMPSMNI-QTHKISMPDVGLNLKAPKLKTDVDVSLPKVEGDLKGPEI---D 1614 E KL P+ K+P + + + ++++PDV L +V LPKV ++K PE+ + Sbjct: 592 EMKL--PEMKLPEVQLPKVPEMAVPDVHLP----------EVQLPKVP-EMKLPEMKLPE 638 Query: 1615 VKAPKM-DVNVGDIDIEGPEGKL-KGPKFKMPEM-HFKAPKISMPDVDLHLKGPKVKGDM 1671 VK PK+ ++ V D+ + PE +L K P+ K+P+M P++ +P+V L PKV Sbjct: 639 VKLPKVPEMAVPDVHL--PEVQLPKVPEMKLPKMPEMAVPEVRLPEVQL----PKVS--- 689 Query: 1672 DVSVPKVEGEMKVPDV---DIKGPKV-DIDAPDVEVHDPDWHL-KMPKMKMPKFSMPGFK 1726 ++ +PKV EM VPDV +++ PKV ++ PD+++ P+ L K+P+M +P +P + Sbjct: 690 EMKLPKVP-EMAVPDVHLPEVQLPKVCEMKVPDMKL--PEIKLPKVPEMAVPDVHLP--E 744 Query: 1727 AEGPEV-DVNLPKADIDVSGPSVDTDAPDLDI-EGPEGKLKGSKFKMPKLNIKAPKVSMP 1784 + P+V ++ LP+ + P V PD+ + + PE KL + P++ +KA K Sbjct: 745 VQLPKVSEIRLPEMQV----PKV----PDVHLPKAPEVKLP----RAPEVQLKATKAEQA 792 Query: 1785 D-VDLNLKGPKLKGEIDASVPELEGDLRGPQVDVKGPFVEAEVPD--VDLECPDAKLKGP 1841 + ++ K PK+ ++P+L G P G AEV V L C ++ G Sbjct: 793 EGMEFGFKMPKM------TMPKL-GRAESPSRGKPGE-AGAEVSGKLVTLPCLQPEVDG- 843 Query: 1842 KFKMPEMHFKAPKISMPDVDLHL----------------KGPKVKGDADVSVPKLEGDLT 1885 E H P +++P V+L L KG +V+G +V+ E Sbjct: 844 -----EAHVGVPSLTLPSVELDLPGALGLQGQVPAAKMGKGERVEGP-EVAAGVREVGFR 897 Query: 1886 GPSV--------GVEVPDVELECPDAKLK-GPKFKMPDMHFKAPKISMPDVDLHLKGPKV 1936 PSV VE+ + LE + K+K KF +P PK++ + + + K+ Sbjct: 898 VPSVEIVTPQLPAVEIEEGRLEMIETKVKPSSKFSLPKFGLSGPKVAKAEAEGAGRATKL 957 Query: 1937 K-GDVDVSVPKL----EGDLTGPSVGVEVPDVELECPDAKLKGPKFKMPEMHFKTPKISM 1991 K +S+PK E + G +P ++L P L + H + K+ + Sbjct: 958 KVSKFAISLPKARVGAEAEAKGAGEAGLLPALDLSIPQLSL--------DAHLPSGKVEV 1009 Query: 1992 PDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKMDIDAPDVDVHGPDW--HLKMP 2049 DL KGP+ ++PK V D + ++ +++ G W +KMP Sbjct: 1010 AGADLKFKGPRF------ALPK----FGVRGRDTEAAELVPGVAELEGKGWGWDGRVKMP 1059 Query: 2050 KMKMPKFSM--------------PGFKAEGPEVDVNLPKADVVVSGPKVD------VEVP 2089 K+KMP F + PG KAE V + +P+ ++V G + + V V Sbjct: 1060 KLKMPSFGLARGKEAEVQGDRASPGEKAESTAVQLKIPEVELVTLGAQEEGRAEGAVAVS 1119 Query: 2090 DVSLEGPEGKLKGPKLKMPEMHFKAPKISMPDVDLHLKGPKVKGDVDVSLPKLEGDLTGP 2149 + L G + G + E H + MP + + L ++ G + P + T P Sbjct: 1120 GMQLSGLKVSTAGQVVT--EGHDAG--LRMPPLGISLPQVELTGFGEAGTPGQQAQSTVP 1175 Query: 2150 SVD------VEVPDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMD 2203 S + V+VP V L P A++ G + + E FK P +++P + L++ + + Sbjct: 1176 SAEGTAGYRVQVPQVTLSLPGAQVAGGELLVGEGVFKMPTVTVPQLELDVGLSREAQAGE 1235 Query: 2204 VSVPKVEGEMKVPDVDIRGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKGEGPEV 2263 + + +K+P + R +V + + G + + + +P + G E Sbjct: 1236 AATGEGGLRLKLPTLGARA-RVGGEGAEEQPPGAE---RTFCLSLPDVELSPSGGNHAEY 1291 Query: 2264 DVNLPKADVDVSGPKVDVEVPDVSL-EGPEGKLKGPKFKMPEMHFKTPKISMPDVDFN-- 2320 V + + +G K+ V +P L EG +G K K+PK+ +P V F+ Sbjct: 1292 QVAEGEGE---AGHKLKVRLPRFGLVRAKEGAEEGEK-------AKSPKLRLPRVGFSQS 1341 Query: 2321 --LKGPKIKGDVDVSAPKLEGELKGP-----ELDVKGPKLDADMPEVAVEGPNGKWKTPK 2373 + G + + EG +G + V+ P++ P A G G PK Sbjct: 1342 EMVTGEGSPSPEEEEEEEEEGSGEGASGRRGRVRVRLPRVGLAAPSKASRGQEGD-AAPK 1400 Query: 2374 FKMPDMHFKAPKISMPDLDLHLKSPKAK 2401 + + K+PK P + L SPKA+ Sbjct: 1401 SPVRE---KSPKFRFPRVSL---SPKAR 1422 Score = 227 bits (578), Expect = 3e-58 Identities = 364/1467 (24%), Positives = 653/1467 (44%), Gaps = 303/1467 (20%) Query: 3653 KLKGPKFKMPEMNIKA----PKISMPDFDLNLKGPKMKGDVVVSLPKVEGDLKGPEVD-I 3707 ++KGP+ K+ ++NI++ K M L + DV S PK +G + + + Sbjct: 116 EIKGPRAKVAKLNIQSLSPVKKKKMVPGALGVPADLAPVDVEFSFPKFSRLRRGLKAEAV 175 Query: 3708 KGP------KVDIDTPDINI-----EGSEGKFKGP-----KFKIPEMHLKAPKISMPDID 3751 KGP + + P + + E + K K+ + + P ++ Sbjct: 176 KGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEVAAGARFTAPQVE 235 Query: 3752 LNLKGPKVKGDVDVSLPKMEGDLKGPEVDIKG------PKVDINAPDVD-VQGPDWHLKM 3804 L GP++ G +V +P++ P + G P + + AP V+ P +++ Sbjct: 236 L--VGPRLPG-AEVGVPQVSAPKAAPSAEAAGGFALHLPTLGLGAPAPPAVEAPAVGIQV 292 Query: 3805 PKVKMPKF-------SMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEG----PE 3853 P+V++P ++P + V V +P D+ VD+ +P +E PE Sbjct: 293 PQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLALPGAEVEARGEAPE 352 Query: 3854 GKLKGPKFKMP-------------------EMNIKAPKISMPDIDLNLKGPKVKGDMDVS 3894 LK P+ P E +K P++ MP L+L P+ + Sbjct: 353 VALKMPRLSFPRFGARAKEVAEAKVAKVSPEARVKGPRLRMPTFGLSLLEPR-----PAA 407 Query: 3895 LPKVEGDMQVPDLDIKGPKVDINAPDVDV-RGPDWHL-KMPKIKMPKISMPGFKGEGPEV 3952 VE +++P + + + ++ P+V V +GP+ L K P++K+PK+ PEV Sbjct: 408 PEVVESKLKLPTIKMPSLGIGVSGPEVKVPKGPEVKLPKAPEVKLPKVPEAAL----PEV 463 Query: 3953 ---DVNLPKADLDVSGPKV-DVDVPDVNIEGPDAKL-KGPKFKMPEM-NIKAPKISMPDF 4006 +V LPK ++ PKV ++ VP+V + P+ +L K + K+P++ + P++ +P+ Sbjct: 464 RLPEVELPKVS-EMKLPKVPEMAVPEVRL--PEVELPKVSEMKLPKVPEMAVPEVRLPEV 520 Query: 4007 DL----HLKGPKVKGDV-------DVSLPKMEGDLKAPEV-DIKGPKV---DIDAPDV-D 4050 L +K PKV +V LPK+ ++K PEV ++ P+V ++ P V + Sbjct: 521 QLLKVSEMKLPKVPEMAVPEVRLPEVQLPKVS-EMKLPEVSEVAVPEVRLPEVQLPKVPE 579 Query: 4051 VHGPDWHL-KMPKVKMPKFSMPGFK-GEGPEV---DVNLPKADIDVSGPKV-DIDTPDID 4104 + P+ L K+P++K+P+ +P + + PE+ DV+LP+ + PKV ++ P++ Sbjct: 580 MKVPEMKLPKVPEMKLPEMKLPEVQLPKVPEMAVPDVHLPEVQL----PKVPEMKLPEMK 635 Query: 4105 IHGPEGKL-KGPKFKMPDLHLKAPKISMPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPEV 4163 + PE KL K P+ +PD+HL P++ +P+V +K PKM ++++P+V + PEV Sbjct: 636 L--PEVKLPKVPEMAVPDVHL--PEVQLPKVP-EMKLPKMP---EMAVPEV----RLPEV 683 Query: 4164 DIKGPKV-DIDVPDV-DVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSG 4221 + PKV ++ +P V ++ PD HL P+V++PK E D+ LP+ L Sbjct: 684 QL--PKVSEMKLPKVPEMAVPDVHL--PEVQLPKVC------EMKVPDMKLPEIKL---- 729 Query: 4222 PKV-DIDVPDVNIEGPDAKL-KGPKFKMPEMNIKAPKISMPDFDLHL-KGPKVKGDVDVS 4278 PKV ++ VPDV++ P+ +L K + ++PEM + PK+ D+HL K P+VK Sbjct: 730 PKVPEMAVPDVHL--PEVQLPKVSEIRLPEMQV--PKVP----DVHLPKAPEVK------ 775 Query: 4279 LPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMP-----GFKGE- 4332 LP+ PEV +K K + G ++ KMPK+ MPK G GE Sbjct: 776 LPRA------PEVQLKATKAE------QAEGMEFGFKMPKMTMPKLGRAESPSRGKPGEA 823 Query: 4333 GPDVD---VTLPKADIEISG-----------PKVDIDAPD-VSIEG--PDAKL-KGPKFK 4374 G +V VTLP E+ G P V++D P + ++G P AK+ KG + + Sbjct: 824 GAEVSGKLVTLPCLQPEVDGEAHVGVPSLTLPSVELDLPGALGLQGQVPAAKMGKGERVE 883 Query: 4375 MPEMNIKAPKISMPDIDFNLKGPKVKGDVDVSLPKVE---GDLKGPEIDIKGPSLDIDTP 4431 PE+ + ++ F + ++ V LP VE G L+ E +K PS P Sbjct: 884 GPEV-----AAGVREVGFRVPSVEI---VTPQLPAVEIEEGRLEMIETKVK-PSSKFSLP 934 Query: 4432 DVNIEGP-------EGKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKG---DVDVSL 4481 + GP EG + K K+ + I PK + + KG G +D+S+ Sbjct: 935 KFGLSGPKVAKAEAEGAGRATKLKVSKFAISLPKARV-GAEAEAKGAGEAGLLPALDLSI 993 Query: 4482 PKVESDLKGP--EVDIEGPEGKLKGPKFKMPDVHFKSPQISMSDIDLNLKGPKIKGDMDI 4539 P++ D P +V++ G + K KGP+F +P + +++ + G Sbjct: 994 PQLSLDAHLPSGKVEVAGADLKFKGPRFALPKFGVRGRDTEAAEL--------VPG---- 1041 Query: 4540 SVPKLEGDLKGPKVDVKGPKVGIDTPDIDIHGPEGKLKGPKFKMPD-LHLKAPKISMPEV 4598 V +LEG G VK PK+ + + + G E +++G + + A ++ +PEV Sbjct: 1042 -VAELEGKGWGWDGRVKMPKLKMPSFGL-ARGKEAEVQGDRASPGEKAESTAVQLKIPEV 1099 Query: 4599 DLNLKGPKVKGDMDISLPKVEGDLKGPEVDIRDPKVDIDVPDVDVQGPDWHLKMPK--VK 4656 +L G + +G + EG + + + KV V +G D L+MP + Sbjct: 1100 ELVTLGAQEEG-------RAEGAVAVSGMQLSGLKVS-TAGQVVTEGHDAGLRMPPLGIS 1151 Query: 4657 MPKFSMPGFKGE----GPDVDVNLPKADIDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMP 4712 +P+ + GF GE G +P A+ +G + V VP V + P A++ G + + Sbjct: 1152 LPQVELTGF-GEAGTPGQQAQSTVPSAE-GTAGYR--VQVPQVTLSLPGAQVAGGELLVG 1207 Query: 4713 EMSIKAPKISMPDIDLNL---------KGPKVKGDVDVTLPKVEGDLKGPEADIKGPKVD 4763 E K P +++P ++L++ + +G + + LP + G A + G + Sbjct: 1208 EGVFKMPTVTVPQLELDVGLSREAQAGEAATGEGGLRLKLPTL-----GARARVGGEGAE 1262 Query: 4764 INTPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVSLPKADIDVSGPKVDVDIPDV 4823 P + + L +P V++ G + V+ + + +G K+ V +P Sbjct: 1263 EQPPGAE---RTFCLSLPDVELSPSG-----GNHAEYQVAEGEGE---AGHKLKVRLPRF 1311 Query: 4824 NI----EGPD--AKLKGPKFKMPEINIKAPKI----SIPDVDLDLKGPKVKGDFDVSVPK 4873 + EG + K K PK ++P + ++ P + + + + S + Sbjct: 1312 GLVRAKEGAEEGEKAKSPKLRLPRVGFSQSEMVTGEGSPSPEEEEEEEEEGSGEGASGRR 1371 Query: 4874 VEGTLKGPEVDLKGPRLDFEGPD--------AKLSGPSLKMPSLEISAPKVTAPDVD--- 4922 ++ P V L P G + + P + P + +S PK + D Sbjct: 1372 GRVRVRLPRVGLAAPSKASRGQEGDAAPKSPVREKSPKFRFPRVSLS-PKARSGSGDQEE 1430 Query: 4923 --LHLKAPKIGFS-----GP-KLEGGE 4941 L ++ P +GFS GP ++EG + Sbjct: 1431 GGLRVRLPSVGFSETGAPGPARMEGAQ 1457 Score = 211 bits (538), Expect = 1e-53 Identities = 378/1619 (23%), Positives = 674/1619 (41%), Gaps = 409/1619 (25%) Query: 2998 DIRGPQVDIDVPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPK 3057 +I+GP+ + ++ P + K KM +PG G V +L D++ S PK Sbjct: 116 EIKGPRAKVAKLNIQSLSP-----VKKKKM----VPGALG----VPADLAPVDVEFSFPK 162 Query: 3058 VDIDVPDVNIEGPEGKLKGP----KFKMPEMNIKAPKISMPDIDLNLKGP---KVKGDMD 3110 + E +G + + ++P + ++ L P K K + + Sbjct: 163 FSRLRRGLKAEAVKGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAE 222 Query: 3111 VSLPKVEGDMKVPDVDIKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISMPGFKGEGPEV 3170 V+ P V++ GP++ P + +P++ PK + P + G Sbjct: 223 VA---AGARFTAPQVELVGPRL-----------PGAEVGVPQVSAPKAA-PSAEAAGGFA 267 Query: 3171 DVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDLDLNLKG 3230 ++LP L P +E P ++ P+ ++P + ++P L+ Sbjct: 268 -LHLPTLGLGAPAPPA--------VEAPAVGIQVPQVELPALPSLPTLPTLPCLETR--- 315 Query: 3231 PKMKGEVDVSLANVEGDLKGPALDIKGPKIDVDAPDIDIHGPDAKLKGPKLKMPDMHVNM 3290 +G V V + P LD+ P + VD + + G + + +G + P++ + M Sbjct: 316 ---EGAVSVVV---------PTLDVAAPTVGVD---LALPGAEVEARG---EAPEVALKM 357 Query: 3291 PKISMPEIDLNLKG------SKLKGDVDVSGPKLEGDIKAPSLDIKGPEVDVSGPKLNIE 3344 P++S P K +K+ + V GP+L + P+ + E + P++ +E Sbjct: 358 PRLSFPRFGARAKEVAEAKVAKVSPEARVKGPRL----RMPTFGLSLLEPRPAAPEV-VE 412 Query: 3345 GKSKKSRFKLPKFNF--SGSKVQTPE-VDVK-GKKPDIDITGPKV------DINAPDVEV 3394 K K K+P SG +V+ P+ +VK K P++ + PKV ++ P+VE+ Sbjct: 413 SKLKLPTIKMPSLGIGVSGPEVKVPKGPEVKLPKAPEVKL--PKVPEAALPEVRLPEVEL 470 Query: 3395 QGKVKGSKFKMPFL-SISSPKVSMPDVELNLKSPKVKGDLDIAGPNLEGDFKGPKV-DIK 3452 K S+ K+P + ++ P+V +P+VEL PKV + K PKV ++ Sbjct: 471 P---KVSEMKLPKVPEMAVPEVRLPEVEL----PKVS------------EMKLPKVPEMA 511 Query: 3453 APEVNLNAPDVDVHGPDWNLKMPKMKMPKFSVSGLKAEGPDVAVDLPKGDINIEGPSMNI 3512 PEV L P+V + LK+ +MK+PK P++AV Sbjct: 512 VPEVRL--PEVQL------LKVSEMKLPKV---------PEMAV---------------- 538 Query: 3513 EGPDLNVEGPEGGL-KGPKFKMPDMN-IKAPKISMPDIDLNLKGPKVKGDVDISLPKLEG 3570 P++ + PE L K + K+P+++ + P++ +P++ L K P++K ++ LPK+ Sbjct: 539 --PEVRL--PEVQLPKVSEMKLPEVSEVAVPEVRLPEVQLP-KVPEMKVP-EMKLPKVP- 591 Query: 3571 DLKGPEV---DIKGPKVDINAPDVDVHGPDWHL-KMPKVKMPKFSMPGFKGEGPEVDVTL 3626 ++K PE+ +++ PKV A DVH P+ L K+P++K+P+ +P +V L Sbjct: 592 EMKLPEMKLPEVQLPKVPEMAVP-DVHLPEVQLPKVPEMKLPEMKLP---------EVKL 641 Query: 3627 PKADIDISGPNVDVDVPDVNIEGPDAKL-KGPKFKMPEM-NIKAPKISMPDFDLNLKGPK 3684 PK ++ VPDV++ P+ +L K P+ K+P+M + P++ +P+ L PK Sbjct: 642 PKVP--------EMAVPDVHL--PEVQLPKVPEMKLPKMPEMAVPEVRLPEVQL----PK 687 Query: 3685 MKGDVVVSLPKVEGDLKGPEVDIKGPKVDIDTPDINIEGSEGKFKGPKFKIPEMHL-KAP 3743 + + LPKV PE+ + D+ P++ + + K P K+PE+ L K P Sbjct: 688 VSE---MKLPKV------PEMAVP----DVHLPEVQLP-KVCEMKVPDMKLPEIKLPKVP 733 Query: 3744 KISMPDIDL-NLKGPKVKGDVDVSLPKMEGDL-------KGPEVDI-KGPKVDINAPDVD 3794 ++++PD+ L ++ PKV ++ LP+M+ K PEV + + P+V + A + Sbjct: 734 EMAVPDVHLPEVQLPKVS---EIRLPEMQVPKVPDVHLPKAPEVKLPRAPEVQLKATKAE 790 Query: 3795 -VQGPDWHLKMPKVKMPKFSMP-----GFKGE-GPDVD---VNLPKADLDVSG------- 3837 +G ++ KMPK+ MPK G GE G +V V LP +V G Sbjct: 791 QAEGMEFGFKMPKMTMPKLGRAESPSRGKPGEAGAEVSGKLVTLPCLQPEVDGEAHVGVP 850 Query: 3838 ----PKVDIDVPDV----------------NIEGPE--GKLKGPKFKMPEMNIKAPKISM 3875 P V++D+P +EGPE ++ F++P + I P++ Sbjct: 851 SLTLPSVELDLPGALGLQGQVPAAKMGKGERVEGPEVAAGVREVGFRVPSVEIVTPQLPA 910 Query: 3876 PDID---LNLKGPKVKGDMDVSLPKVEGDMQVPDLDIKGPKVDINAPDVDVRGPDWHLKM 3932 +I+ L + KVK SLPK + GPKV + + G LK+ Sbjct: 911 VEIEEGRLEMIETKVKPSSKFSLPK---------FGLSGPKVA--KAEAEGAGRATKLKV 959 Query: 3933 PK--IKMPKISMPG---FKGEG-----PEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDA 3982 K I +PK + KG G P +D+++P+ LD P V+V G D Sbjct: 960 SKFAISLPKARVGAEAEAKGAGEAGLLPALDLSIPQLSLDAHLPSGKVEVA-----GADL 1014 Query: 3983 KLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKV 4042 K KGP+F +P+ ++ + V G E++ KG Sbjct: 1015 KFKGPRFALPKFGVRGRDTEAAEL--------VPG--------------VAELEGKG--- 1049 Query: 4043 DIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVNLPKADIDVSGPKVDIDTPD 4102 G D +KMPK+KMP F + G E +V +A Sbjct: 1050 ---------WGWDGRVKMPKLKMPSFGL----ARGKEAEVQGDRAS-------------- 1082 Query: 4103 IDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPE 4162 G K + + LK P EV+L G + +G + ++ L G + Sbjct: 1083 ----------PGEKAESTAVQLKIP-----EVELVTLGAQEEGRAEGAVAVSGMQLSGLK 1127 Query: 4163 VDIKGPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGP 4222 V G +V + D ++ P + +P+V++ F G G+ +P A+ +G Sbjct: 1128 VSTAG-QVVTEGHDAGLRMPPLGISLPQVELTGFGEAGTPGQ--QAQSTVPSAE-GTAGY 1183 Query: 4223 KVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHL---------KGPKVKG 4273 +V VP V + P A++ G + + E K P +++P +L + + +G Sbjct: 1184 RV--QVPQVTLSLPGAQVAGGELLVGEGVFKMPTVTVPQLELDVGLSREAQAGEAATGEG 1241 Query: 4274 DVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVD----VHGPDWHLKMPKVKMPKFSMPGF 4329 + + LP + G + G + P + + PD L ++ + Sbjct: 1242 GLRLKLPTL-----GARARVGGEGAEEQPPGAERTFCLSLPDVELSPSGGNHAEYQVAEG 1296 Query: 4330 KGE-GPDVDVTLPKADIEISGPKVDIDAPDVSIEGPDAKLKGPKFKMPEMNIKAPKISMP 4388 +GE G + V LP+ + + A + + EG K K PK ++P + ++ Sbjct: 1297 EGEAGHKLKVRLPRFGL--------VRAKEGAEEG--EKAKSPKLRLPRVGFSQSEM--- 1343 Query: 4389 DIDFNLKGPKVKGDVDVSLPKVEGDLKGP-----EIDIKGPSLDIDTPDVNIEGPEG--- 4440 + G + + EG +G + ++ P + + P G EG Sbjct: 1344 -----VTGEGSPSPEEEEEEEEEGSGEGASGRRGRVRVRLPRVGLAAPSKASRGQEGDAA 1398 Query: 4441 -----KLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKV---ESDLKGP 4491 + K PKF+ P +++ +PK G + +G + V LP V E+ GP Sbjct: 1399 PKSPVREKSPKFRFPRVSL-SPKARSG------SGDQEEGGLRVRLPSVGFSETGAPGP 1450 Score = 180 bits (456), Expect = 4e-44 Identities = 336/1396 (24%), Positives = 576/1396 (41%), Gaps = 289/1396 (20%) Query: 4671 DVDVNLPKADIDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMSIKAPKISMPDIDLNL 4730 DV+ + PK G K + V +L+ P+ ++ E++ +A + Sbjct: 155 DVEFSFPKFSRLRRGLKAEAVKGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPP 214 Query: 4731 KGPKVKGDVDV----TLPKVEGDLKGPEADIKGPKVDINTPDVDVHGPDWHLKMPKVKMP 4786 + KV+ +V T P+VE L GP P ++ P V PK Sbjct: 215 RKAKVEAEVAAGARFTAPQVE--LVGPRL----PGAEVGVPQVSA---------PKAAPS 259 Query: 4787 KFSMPGFKGEGPDVDVSLPKADIDVSGPKVDVDIPDVNIEGPDAKLKGPKFKMPEINIKA 4846 + GF P + + P A V P V + +P V + + P E A Sbjct: 260 AEAAGGFALHLPTLGLGAP-APPAVEAPAVGIQVPQVELPALPSLPTLPTLPCLETREGA 318 Query: 4847 PKISIPDVDLDLKGPKVKGDFDVSVPKVEGTLKGPEVDLKGPRLDFE------------- 4893 + +P LD+ P V D + +VE + PEV LK PRL F Sbjct: 319 VSVVVPT--LDVAAPTVGVDLALPGAEVEARGEAPEVALKMPRLSFPRFGARAKEVAEAK 376 Query: 4894 ----GPDAKLSGPSLKMPS--LEISAPKVTAPD-VDLHLKAPK-------IGFSGPKL-- 4937 P+A++ GP L+MP+ L + P+ AP+ V+ LK P IG SGP++ Sbjct: 377 VAKVSPEARVKGPRLRMPTFGLSLLEPRPAAPEVVESKLKLPTIKMPSLGIGVSGPEVKV 436 Query: 4938 -EGGEVDL-KGPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKFGFGAKSPKADIKSPS 4995 +G EV L K P+V+ P + P+ + P+V++P+ + PK +++K P Sbjct: 437 PKGPEVKLPKAPEVKLPKV------PEAAL--PEVRLPEVELPKV--------SEMKLPK 480 Query: 4996 L-DVTVPEAEL-NLETPEISVGGKGKKSKFKMPKIHMSGPKIKAKKQGFDLNVPGGEIDA 5053 + ++ VPE L +E P++S K + +P++ + P+++ K ++ +P Sbjct: 481 VPEMAVPEVRLPEVELPKVSEMKLPKVPEMAVPEVRL--PEVQLLKVS-EMKLP------ 531 Query: 5054 SLKAPDVDV-NIAGPDAAL-KV-DVKSPKTKKTMFGKMYFPDVEF----DIKSPKFK--- 5103 K P++ V + P+ L KV ++K P+ + ++ P+V+ ++K P+ K Sbjct: 532 --KVPEMAVPEVRLPEVQLPKVSEMKLPEVSEVAVPEVRLPEVQLPKVPEMKVPEMKLPK 589 Query: 5104 -AEAPLPSPKLEGELQAPDL-ELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGDLKG 5161 E LP KL E+Q P + E+++P +H+ + + K P++K+P++ + ++K Sbjct: 590 VPEMKLPEMKLP-EVQLPKVPEMAVPDVHLPEVQL-PKVPEMKLPEMKLP------EVKL 641 Query: 5162 PKVQANLGAPDINIEGLD----AKVKTPSF-GISAPQVSIPDVNV----NLKGPKI-KGD 5211 PKV + PD+++ + ++K P ++ P+V +P+V + +K PK+ + Sbjct: 642 PKV-PEMAVPDVHLPEVQLPKVPEMKLPKMPEMAVPEVRLPEVQLPKVSEMKLPKVPEMA 700 Query: 5212 VPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVH---AQLPSLEGDLRG 5268 VP V L P+V L ++K P +P+I +P V E +VH QLP + ++R Sbjct: 701 VPDVHL--PEVQLP-KVCEMKVPDMKLPEIKLPKVP-EMAVPDVHLPEVQLPKV-SEIRL 755 Query: 5269 PDVKL-EGPDVSL-KGPGVDLP------------------SVNLSMPKVSGPDLDLNLKG 5308 P++++ + PDV L K P V LP MPK++ P L + Sbjct: 756 PEMQVPKVPDVHLPKAPEVKLPRAPEVQLKATKAEQAEGMEFGFKMPKMTMPKLG-RAES 814 Query: 5309 PS--LKGDLDASVPSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVG----APD 5362 PS G+ A V V P L V G+ VG + +P ++ +G P Sbjct: 815 PSRGKPGEAGAEVSGKLVTLPCLQ-PEVDGEAHVGVPSLTLPSVELDLPGALGLQGQVPA 873 Query: 5363 VTL-RGPSLQGDLAVSG----DIKCPKVSVGAPDL-SLEASEGSIKL--------PKMKL 5408 + +G ++G +G + P V + P L ++E EG +++ K L Sbjct: 874 AKMGKGERVEGPEVAAGVREVGFRVPSVEIVTPQLPAVEIEEGRLEMIETKVKPSSKFSL 933 Query: 5409 PQFGISTPGSDLHVNAKGPQVS-GELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGA 5467 P+FG+S GP+V+ E +G G LK + F + PK + +GA Sbjct: 934 PKFGLS-----------GPKVAKAEAEGAGRATKLKVSK-------FAISLPKAR--VGA 973 Query: 5468 TGEIKGPTVGGGLPGIGVQ----GLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEI 5523 E KG G LP + + L+ +L ++ +G D+ G LP + G + Sbjct: 974 EAEAKGAGEAGLLPALDLSIPQLSLDAHLPSGKVEVAGADLKFKGPRFALPKFGVRGRDT 1033 Query: 5524 KGG--------LKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGG 5575 + L+G G+ G +K P+F +A + ++G + G Sbjct: 1034 EAAELVPGVAELEGKGWGWDGRVKMPKLKMPSFGLARGKE---AEVQGDRASPGEKAES- 1089 Query: 5576 VSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGG----VKGG 5631 +A + + E L G+ E + + + G+ SG KV +G Sbjct: 1090 -TAVQLKIPEVELVTLGAQEEGRA---------EGAVAVSGMQLSGLKVSTAGQVVTEGH 1139 Query: 5632 QIGLQAPGLSVSGPQGHLESGSGKVTFP-----------------KMKIPKFTFS--GRE 5672 GL+ P L +S PQ L +G G+ P ++++P+ T S G + Sbjct: 1140 DAGLRMPPLGISLPQVEL-TGFGEAGTPGQQAQSTVPSAEGTAGYRVQVPQVTLSLPGAQ 1198 Query: 5673 LVGREMGV--------DVHFPKAEASI----QAGAGDGEWEESEVKLKKSKIKMPKFNFS 5720 + G E+ V V P+ E + +A AG+ E ++L K+P Sbjct: 1199 VAGGELLVGEGVFKMPTVTVPQLELDVGLSREAQAGEAATGEGGLRL-----KLPTLGAR 1253 Query: 5721 KPKGKGGV------------TGSPEASISGSKGDLKSSKASLGSLEGEAEAEASSPKGKF 5768 G G P+ +S S G+ + + G EGEA + +F Sbjct: 1254 ARVGGEGAEEQPPGAERTFCLSLPDVELSPSGGNHAEYQVAEG--EGEAGHKLKVRLPRF 1311 Query: 5769 SLF----------KSKKPRHR--SNSFSDEREFSGPSTPTGTLEFEGGEVSLEGGKVKGK 5816 L K+K P+ R FS +G +P+ E E E G G+ Sbjct: 1312 GLVRAKEGAEEGEKAKSPKLRLPRVGFSQSEMVTGEGSPSPEEEEEEEEEG-SGEGASGR 1370 Query: 5817 HGKLKFG-TFGGLGSKSKGHYEVTGS-------DDETGKLQGSGVSLASKKSRLSSSSSN 5868 G+++ GL + SK G +++ K + VSL S K+R S Sbjct: 1371 RGRVRVRLPRVGLAAPSKASRGQEGDAAPKSPVREKSPKFRFPRVSL-SPKARSGSGDQE 1429 Query: 5869 DSGNKVGIQLPEVELS 5884 + G +V +LP V S Sbjct: 1430 EGGLRV--RLPSVGFS 1443 Score = 60.8 bits (146), Expect = 4e-08 Identities = 91/390 (23%), Positives = 149/390 (38%), Gaps = 92/390 (23%) Query: 5187 FGISAPQVSIPDVNVNLKGP-KIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSM------- 5238 + I P+ + +N+ P K K VP G G DL + + FPKFS Sbjct: 115 YEIKGPRAKVAKLNIQSLSPVKKKKMVP--GALGVPADLAPVDVEFSFPKFSRLRRGLKA 172 Query: 5239 ------------------PKIGIPGVKMEGGGAEVHAQLP-----SLEGDLRGPDVKLEG 5275 P++ + V E A + A P +E ++ + Sbjct: 173 EAVKGPVPAAPARRRLQLPRLRVREVAEEAQAARLAAAAPPPRKAKVEAEV-AAGARFTA 231 Query: 5276 PDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLSG-V 5334 P V L GP LP + +P+VS P PS + + +H P L L Sbjct: 232 PQVELVGP--RLPGAEVGVPQVSAPK-----AAPSAE-----AAGGFALHLPTLGLGAPA 279 Query: 5335 GGKMQVGGDGVKVPGIDATT------------------KLNVGAPDVTLRGPSLQGDLAV 5376 ++ G++VP ++ ++V P + + P++ DLA+ Sbjct: 280 PPAVEAPAVGIQVPQVELPALPSLPTLPTLPCLETREGAVSVVVPTLDVAAPTVGVDLAL 339 Query: 5377 SGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGP 5436 G + EA E ++K+P++ P+FG AK +VS E + Sbjct: 340 PG---------AEVEARGEAPEVALKMPRLSFPRFGARAKEV---AEAKVAKVSPEAR-- 385 Query: 5437 GVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPG 5496 +KGPR+ P +L P+ ++K PT+ GIGV G E +++P Sbjct: 386 -----VKGPRLRMPTFGLSLLEPRPAAPEVVESKLKLPTIKMPSLGIGVSGPE--VKVP- 437 Query: 5497 IKSSGCDVNLP-GVNVKLP-TGQISGPEIK 5524 G +V LP VKLP + + PE++ Sbjct: 438 ---KGPEVKLPKAPEVKLPKVPEAALPEVR 464 >gi|55769541 AHNAK nucleoprotein isoform 2 [Homo sapiens] Length = 149 Score = 234 bits (596), Expect = 2e-60 Identities = 114/115 (99%), Positives = 115/115 (100%) Query: 1 MEKEETTRELLLPNWQGSGSHGLTIAQRDDGVFVQEVTQNSPAARTGVVKEGDQIVGATI 60 MEKEETTRELLLPNWQGSGSHGLTIAQRDDGVFVQEVTQNSPAARTGVVKEGDQIVGATI Sbjct: 1 MEKEETTRELLLPNWQGSGSHGLTIAQRDDGVFVQEVTQNSPAARTGVVKEGDQIVGATI 60 Query: 61 YFDNLQSGEVTQLLNTMGHHTVGLKLHRKGDRSPEPGQTWTREVFSSCSSEVVLS 115 YFDNLQSGEVTQLLNTMGHHTVGLKLHRKGDRSPEPGQTWTREVFSSCSSEVVL+ Sbjct: 61 YFDNLQSGEVTQLLNTMGHHTVGLKLHRKGDRSPEPGQTWTREVFSSCSSEVVLN 115 >gi|110349719 titin isoform N2-A [Homo sapiens] Length = 33423 Score = 94.4 bits (233), Expect = 3e-18 Identities = 309/1283 (24%), Positives = 512/1283 (39%), Gaps = 208/1283 (16%) Query: 1056 KMPEMHFRAPKMSLPDVDLDLKGPKMKGNVDISAPKIEGEMQVPDVDIRGPKVDIKAPDV 1115 K+PE+ P+ +P+ + PK K P++ + + KV + P Sbjct: 9949 KVPEV----PRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPE--------EKVPVLIPKK 9996 Query: 1116 EGQGLDWSLKIPKMKMPKFSMP---SLKGEGPEVDV-NLPKADVVVSGPKVDIEAPDVSL 1171 E ++PK +P+ +P K E P V +PK V KV + AP + Sbjct: 9997 EKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEK--KVPVPAPK-KV 10053 Query: 1172 EGPEGKL-KGPKFKMPEMHFKTP---KISMPDVDLHLKGPKVKGDVDVSVPKVEG----E 1223 E P K+ + PK +PE TP K+ P + K V V V++P+ E E Sbjct: 10054 EAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVP--VPVALPQEEEVLFEE 10111 Query: 1224 MKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMP--KFSMPGFKGEGREVDVNLPKA 1281 VP+ E+ + ++ + EV + + + ++P + +P + E + +P+ Sbjct: 10112 EIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEE 10171 Query: 1282 DI--DVSGPKVDVE--VPDVSLEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLNLKG--- 1334 ++ +V PKV V VP++ + E K+ PK + +AP +P+V ++ Sbjct: 10172 EVLPEVK-PKVPVPAPVPEIKKKVTEKKVVIPKKE------EAPPAKVPEVPKKVEEKRI 10224 Query: 1335 --PKLKGDVDVSLPEVEGEMKVPDVDIKGPKVDISAPDVDVHGPDWHLKMPKVKMPKFSM 1392 PK + + V + E E + + +I P+ S +V+ P ++ K +P+ Sbjct: 10225 ILPKEEEVLPVEVTEEPEEEPISEEEI--PEEPPSIEEVEEVAPPRVPEVIKKAVPEAPT 10282 Query: 1393 PGFKGEGPEVDVKLPKADVDVSGPKMDAEVPDVNIEGPDAKLKGPKFKMPEMSI-KPQKI 1451 P K V+ P A V P+ VP E P AK+ K+PE + P+K Sbjct: 10283 PVPK------KVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKE 10336 Query: 1452 SIPDV-GLHLKGPKMKGDY--DVTVPK------VEGEIKAPDVDIKGPKVDINAPDVEVH 1502 ++P G + K+ + +V V + VE E++ + + +V+ + E H Sbjct: 10337 AVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFH 10396 Query: 1503 GPDWHLKMP--------KVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPDVN 1554 + +K+ +V+ + F+ E EV PKA GP++ + + Sbjct: 10397 EVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEV-FEKPKAP--PKGPEISEKI--IP 10451 Query: 1555 LEAPEGKL---KGPKFKMPSMN---IQTHKISMPDVGLNLKAPKL-KTDVDVSLPKVEGD 1607 + P K+ K P K+P + + K+ +P+ P++ T V LP E Sbjct: 10452 PKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPE------EPRVPPTKVPEVLPPKE-- 10503 Query: 1608 LKGPEIDVKAPKMDVNVGDIDIEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKV 1667 PE V P P K + P K+PE APK +P+ + + PK Sbjct: 10504 -VVPEKKVPVP-------------PAKKPEAPPPKVPE----APKEVVPEKKVPVPPPKK 10545 Query: 1668 KGDMDVSVPKVE----GEMKVPDVDIKGPKVDIDAPDVEVHDPDWHLKMPKMKMPKFSMP 1723 VP+V E KVP+ PK + P+V + PK +P+ +P Sbjct: 10546 PEVPPTKVPEVPKAAVPEKKVPEA--IPPKPESPPPEVP--------EAPKEVVPEKKVP 10595 Query: 1724 GFKAEGPEV-DVNLPKADIDVSGPSVDTDAPDLDIEGPEGKLKG------SKFKMPKLNI 1776 + PEV V +P+A +V P E P K+ + K+P+ Sbjct: 10596 AAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIP 10655 Query: 1777 KAPKVSMPDVDLNLKGPKLKGEIDASVPELEGDLRGPQVDV--KGPFVEAEVPDVDLECP 1834 P+ P+V + L+ E A V E PQV V K P E + P V + P Sbjct: 10656 PKPESPPPEVFEEPEEVALE-EPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKP 10714 Query: 1835 DAKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDADVSVPKLEGDLTGPSVGVEVP 1894 + P K+PE+ PK +P+ + L PK VP++ ++ P V VP Sbjct: 10715 EL----PPVKVPEV----PKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVV-PEKKVAVP 10765 Query: 1895 DVELECPDAKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDVDVSVPKLEGDLTGP 1954 + E P AK+ P+ + + P + +P+ P+V + + P+ E P Sbjct: 10766 K-KPEVPPAKV--PEVPKKPVLEEKPAVPVPE-RAESPPPEVYEEPEEIAPEEE---IAP 10818 Query: 1955 SVGVEVPDVELECPD----AKLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVKGDMDVS 2010 VP E E P+ A + PK +PE K P I P+ PK Sbjct: 10819 EEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEK--KVPVIKKPEA----PPPK-------- 10864 Query: 2011 VPKVEGEMKVPDVDIKGPKMDIDAPDVDVHGPDWHLK-MPKMKMP-------KFSMPGFK 2062 P+ E ++ P + + P P DV + LK +PK K+P K + K Sbjct: 10865 EPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLK 10924 Query: 2063 AEGPEVDVN--LPKADVVVSGPKVDVEVPDVSLEGPEGKLKGPKLKMPEMHFKAPKISMP 2120 G E V LP+ PK +V + V + PE + PK++ P+ K K ++P Sbjct: 10925 VPGGEKKVRKLLPERK---PEPKEEVVLKSVLRKRPEE--EEPKVE-PKKLEKVKKPAVP 10978 Query: 2121 DVDLHLKGPKVKGDVDV-SLPKLEGDLTGPSVDVEV-PDVELECPDAKLKGPKFKMPEMH 2178 + PK +V+V ++ K E + P+ E+ P + L P+ K K PE Sbjct: 10979 EP----PPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPK------PEAE 11028 Query: 2179 FKTPKISMPDVNLNLKGPKVKGDMDVSVPKVEGEMKVPDVDIRGPKVDIDAPDVDVHGPD 2238 KT I P V + + + V V + E K P + PK I P Sbjct: 11029 VKT--IKPPPV--EPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSP- 11083 Query: 2239 WHLKMPKMKMPKFSMPGFKGEGP 2261 ++ + K+ PG GE P Sbjct: 11084 --IEAERRKL----RPGSGGEKP 11100 Score = 90.5 bits (223), Expect = 4e-17 Identities = 286/1261 (22%), Positives = 509/1261 (40%), Gaps = 188/1261 (14%) Query: 1887 PSVGVEVPDVELE-CPDAKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDVDVSVP 1945 P + V+VP+V + P+ K P K + AP +P+V K P+ K V V +P Sbjct: 9944 PVIPVKVPEVPRKPVPEEKKPVPVPKKKE----APPAKVPEVP---KKPEEK--VPVLIP 9994 Query: 1946 KLEGDLTG--PSVGVE-VPDVELECP-DAKLKGPKFKMPEMHFKTPKISMPDVDLHLKGP 2001 K E P V + VP+ ++ P K++ P K+PE+ PK +P+ + + P Sbjct: 9995 KKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEV----PKKPVPEKKVPVPAP 10050 Query: 2002 KVKGDMDVSVPKVEGEMKVPDVDIKGP-KMDIDAPDVDVHGPDWHLKMPKMKMPKFSMPG 2060 K VP+V ++ +P+ P ++AP V + +P + +P+ Sbjct: 10051 KKVEAPPAKVPEVPKKL-IPEEKKPTPVPKKVEAPPPKVPKKREPVPVP-VALPQEEEVL 10108 Query: 2061 FKAE-GPEVDVNLPKADVVVSGPKVDVEVPDVSLEGPEGKLKGPKLKMPEMHFKAPKISM 2119 F+ E PE +V + +V+ +V E +V E E + ++ E + + + Sbjct: 10109 FEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFV 10168 Query: 2120 PDVDLHLKGPKVKGDVDVSLPKLEGDLTGPSVDVEVPDVELECPDAKLKGPKFKMPEMHF 2179 P+ ++ P+VK V V P P + +V + ++ P K + P K+PE+ Sbjct: 10169 PEEEVL---PEVKPKVPVPAPV-------PEIKKKVTEKKVVIPK-KEEAPPAKVPEV-- 10215 Query: 2180 KTPKISMPDVNLNLKGPKVKGDMDVSVPKVEGEMKVPDVDIRGPKVDIDAPDVDVHGPDW 2239 K+ + L PK + + V V + E + + +I P+ +V+ P Sbjct: 10216 -PKKVEEKRIIL----PKEEEVLPVEVTEEPEEEPISEEEI--PEEPPSIEEVEEVAPP- 10267 Query: 2240 HLKMPKMKMPKFSMPGFKGEGPEVDVNLPKADVDVSGPKVDVEVPDVSLEGPEGKLKGPK 2299 ++P++ K PE +PK V+ KV ++P+ + P K + P Sbjct: 10268 --RVPEV---------IKKAVPEAPTPVPKK-VEAPPAKVSKKIPEEKVPVPVQKKEAPP 10315 Query: 2300 FKMPEMHFKTP--KISMPDVDFNLKGPKIKGDVDVSAPKLEGELKGPELDVKGPKLDADM 2357 K+PE+ K P K+ +P + P KG V K+ + E+ VK +L+ ++ Sbjct: 10316 AKVPEVPKKVPEKKVLVPKKE---AVPPAKGRT-VLEEKVSVAFR-QEVVVK-ERLELEV 10369 Query: 2358 PEVAVEGPNGKWKTPKFKMPDMHFKAPKISMPDLDLHLKSPKAKGEVDVD-VPKLEGDLK 2416 E VE + +F + +F+ + + + L+ + + E V+ V ++ + Sbjct: 10370 VEAEVEEIP---EEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFE 10426 Query: 2417 GPHVDVSGPDIDIEGPEGKLKGPKFKMPDMHFKAPNISMPDVDLNLKGPKIKGDVDVSVP 2476 V+V E P+ KGP+ + K P P + K P K VP Sbjct: 10427 AEEVEV------FEKPKAPPKGPEISEKIIPPKKP----PTKVVPRKEPPAK------VP 10470 Query: 2477 EVEGKLEVPDMNIRGPKVDVNAPDVQAPDWHLKMPKMKMPKFSMPGFKAEGPEVDV-NLP 2535 EV K+ V + +R P+ + P + P+ + PK +P+ +P A+ PE +P Sbjct: 10471 EVPKKIVVEE-KVRVPE-EPRVPPTKVPE--VLPPKEVVPEKKVPVPPAKKPEAPPPKVP 10526 Query: 2536 KADVDISGPKVDIEGPDVNIEGPEGKL-KGPKLKMPEMNI----------------KAPK 2578 +A ++ K P E P K+ + PK +PE + +APK Sbjct: 10527 EAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPK 10586 Query: 2579 ISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKM 2638 +P+ + PK V +P+ P+ + KV + P P ++ Sbjct: 10587 EVVPEKKVPAAPPKKPEVTPVKVPEA------PKEVVPEKKVPVPPPKKPEVPPTKVPEV 10640 Query: 2639 PKVKMPKFSMPGF---KGEGPDGDVKLPKADIDVSGPKVDI-------EGPDVNIEG--- 2685 PKV +P+ +P K E P +V ++ + P ++ P V + Sbjct: 10641 PKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKP 10700 Query: 2686 -PEGKLKGPKFKMPEMN-IKAPKIS---MPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPE 2740 PE K K PE+ +K P++ +P+ + L PK +P+V ++ PE Sbjct: 10701 VPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVV-PE 10759 Query: 2741 VDIKGPKVDIDAPDVDVHGPDWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKADI---DV 2797 + PK + P V P+ K + P + +P + E P +V +I + Sbjct: 10760 KKVAVPKKP-EVPPAKV--PEVPKKPVLEEKPAVPVPE-RAESPPPEVYEEPEEIAPEEE 10815 Query: 2798 SGPKVDVECPDVNIEGPE----GKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDV 2853 P+ + P E PE + PK +PE K P I P+ PK Sbjct: 10816 IAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEK--KVPVIKKPEAP----PPK----- 10864 Query: 2854 DVTGPKVEGDLKGPEVDLKGPKVDIDVPDVNVQGPDWHLK-MPKMKMP-------KFSMP 2905 P+ E ++ P++ + P P +V+ + LK +PK K+P K + Sbjct: 10865 ---EPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELT 10921 Query: 2906 GFKAEGPEVDVN--LPKADVDVSGPKVDVEGPDVNIEGPEGKLKGPKFKMPEMN-IKAPK 2962 K G E V LP+ + PK +V V + PE + PK + ++ +K P Sbjct: 10922 PLKVPGGEKKVRKLLPERKPE---PKEEVVLKSVLRKRPEEE--EPKVEPKKLEKVKKPA 10976 Query: 2963 IPMPDFDLHLKGPKVKGDVDISLPKV-EGDLKGPEVDIRGPQVDIDVPDVGVQGPDWHLK 3021 +P P P K ++ +P V + + K PE + P++ P + + P+ K Sbjct: 10977 VPEP--------PPPKPVEEVEVPTVTKRERKIPE-PTKVPEIK---PAIPLPAPEPKPK 11024 Query: 3022 MPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKM 3081 P+ ++ P + E + + + V G K + P P+G +KG K Sbjct: 11025 -PEAEVKTIKPPPVEPEPTPIAAPVT---VPVVGKKAEAKAPKEEAAKPKGPIKGVPKKT 11080 Query: 3082 P 3082 P Sbjct: 11081 P 11081 Score = 89.4 bits (220), Expect = 1e-16 Identities = 295/1265 (23%), Positives = 498/1265 (39%), Gaps = 215/1265 (16%) Query: 581 PKVKGGVDVTLPRVEGKVKVPEVDVRGP-KVDVSAPDVEAHGPEWNLKMPKMKMPTFSTP 639 P+ K V V + KVPEV + KV V P E P ++PK +P P Sbjct: 9959 PEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVP 10018 Query: 640 ---GAKGEGPDVHMT------LPKGDISISGPKVNVEAPDVNLEGLGGKL---------- 680 K E P + +P+ + + PK VEAP + + KL Sbjct: 10019 VPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPK-KVEAPPAKVPEVPKKLIPEEKKPTPV 10077 Query: 681 ----KGPDVKLPDMSVKTP-KISMPDVDLHVKGTKVKGEYDVTVPKLEGELKGPKVDIDA 735 + P K+P P +++P + + ++ E +V +P+ E L P+ + Sbjct: 10078 PKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEV-LPEEEEVL--PEEEEVL 10134 Query: 736 PDVDVHGPDWHLKMPKMKMPKFSVPGFKAEGPEVDVNLPKADV--DISGPKIDVTAPDVS 793 P+ + P+ P+ + VP + PE + +P+ +V ++ PK+ V AP Sbjct: 10135 PEEEEVLPEEEEIPPEEE----EVPPEEEYVPEEEEFVPEEEVLPEVK-PKVPVPAP--- 10186 Query: 794 IEEPEGKLKGPKFKMPEMNIKVPKISMPDVDLHLKGPNVKGEYDVTMPKVESEIKV---- 849 + E + K+ K +P+ + P +P+V P E + +PK E + V Sbjct: 10187 VPEIKKKVTEKKVVIPKKE-EAPPAKVPEV------PKKVEEKRIILPKEEEVLPVEVTE 10239 Query: 850 -----PDVELKSAKMDIDVPDVEVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKA 904 P E + + + +VE P ++ K +P+ P K V P A Sbjct: 10240 EPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKK------VEAPPA 10293 Query: 905 DVDISGPKVGVEVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGPKVKGEY 964 V P+ V VP E P K+ K+PE + PK + KG V E Sbjct: 10294 KVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPK---KEAVPPAKGRTVLEEK 10350 Query: 965 DMTVPKLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGPEFDVNLSK 1024 + E +K ++++ + E++ + +++ ++ E EF + L + Sbjct: 10351 VSVAFRQEVVVK-ERLELEVVEAEVEEIPEEEEFHEVE--EYFEEGEFHEVEEF-IKLEQ 10406 Query: 1025 ANVDISAPKVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKGPKMKGN 1084 V+ + E E ++ F+ P+ + P++S + + K P K Sbjct: 10407 HRVEEEHRVEKVHRVIEVFEAEEVEV----FEKPKAPPKGPEIS--EKIIPPKKPPTK-- 10458 Query: 1085 VDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLKGEGP 1144 P+ E +VP+V PK + V + ++P K+P+ P K P Sbjct: 10459 ---VVPRKEPPAKVPEV----PKKIVVEEKVR---VPEEPRVPPTKVPEVLPP--KEVVP 10506 Query: 1145 EVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDLHL 1204 E V +P A + P EAP + PE K+ P K PE+ P +P+V Sbjct: 10507 EKKVPVPPAKKPEAPPPKVPEAPKEVV--PEKKVPVPPPKKPEV----PPTKVPEV---- 10556 Query: 1205 KGPKVKGDVDVSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMPKFSM 1264 PK +VP E KVP E PK + P+V + PK +P+ + Sbjct: 10557 --PK------AAVP----EKKVP--EAIPPKPESPPPEVP--------EAPKEVVPEKKV 10594 Query: 1265 PGFKGEGREV-DVNLPKADIDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKAPKI 1323 P + EV V +P+A +V P+ V VP P K + P K+PE+ PK+ Sbjct: 10595 PAAPPKKPEVTPVKVPEAPKEVV-PEKKVPVP------PPKKPEVPPTKVPEV----PKV 10643 Query: 1324 SMPDVDLNLKGPK-LKGDVDVSLPEVEGEMKVPDVDIKGPKVDISAPDVDVHGPDWHLKM 1382 ++P+ K P+ + + PEV E + +V ++ P ++ + + P Sbjct: 10644 AVPE----KKVPEAIPPKPESPPPEVFEEPE--EVALEEPPAEV-VEEPEPAAPPQVTVP 10696 Query: 1383 PKVKMPKFSMPGFKGEGPEV-DVKLPKADVDVSGPKMDAEVPDVNIEGPDAKL-KGPKFK 1440 PK +P+ P + PE+ VK+P+ +V K V E P AK+ + PK Sbjct: 10697 PKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEV 10756 Query: 1441 MPEMSIK-PQKISIPDVGLH--LKGPKMKGDYDVTVPK----------VEGEIKAPDVDI 1487 +PE + P+K +P + K P ++ V VP+ E E AP+ +I Sbjct: 10757 VPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEI 10816 Query: 1488 KGPKVDINAPDVEVHGPDW--------------HLKMPKVKMPKFSMPGFKGEGPEVDMN 1533 P+ + P E P+ K+P +K P+ P + PE + Sbjct: 10817 -APEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPP----KEPEPEKV 10871 Query: 1534 LPKADLGVSGPKVDIDVPDVNLEAPEGKLKG-PKFKMPSMNIQTHKISMPDVGLNLKAPK 1592 + K L P P +++ +LK PK K+P K+ + LK P Sbjct: 10872 IEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTP----LKVPG 10927 Query: 1593 LKTDVDVSLPKVEGDLKGPEIDVKAPKMDVNVGDIDIEGPEGKLKGPKFKMPEMHFKAPK 1652 + V LP+ + PE PK +V + + + PE + PK + P+ K K Sbjct: 10928 GEKKVRKLLPE-----RKPE-----PKEEVVLKSVLRKRPEE--EEPKVE-PKKLEKVKK 10974 Query: 1653 ISMPDVDLHLKGPKVKGDMDVSVPKV-EGEMKVPD----VDIKGPKVDIDAPDVEVHDPD 1707 ++P+ P K +V VP V + E K+P+ +IK P + + AP+ + P Sbjct: 10975 PAVPE------PPPPKPVEEVEVPTVTKRERKIPEPTKVPEIK-PAIPLPAPEPK---PK 11024 Query: 1708 WHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADIDVSGPSVDTDAPDLDIEGPEGKLKGS 1767 ++ +K P PE + V G + AP + P+G +KG Sbjct: 11025 PEAEVKTIKPPPVE--------PEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGV 11076 Query: 1768 KFKMP 1772 K P Sbjct: 11077 PKKTP 11081 Score = 88.6 bits (218), Expect = 2e-16 Identities = 290/1239 (23%), Positives = 492/1239 (39%), Gaps = 167/1239 (13%) Query: 4119 MPDLHLKAPKISMPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPEVDIKGP-KVDIDVPDV 4177 +P + +K P++ V P+ K V V K K PEV K KV + +P Sbjct: 9943 VPVIPVKVPEVPRKPV------PEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKK 9996 Query: 4178 DVQGPDWHLKMPKVKMPKFSMP---GFKGEGPDVDV-NLPKADLDVSGPKVDIDVPDVNI 4233 + P ++PK +P+ +P K E P V +PK V KV + P + Sbjct: 9997 EKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKP--VPEKKVPVPAPK-KV 10053 Query: 4234 EGPDAKL-KGPKFKMPEMNIKAP---KISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGP 4289 E P AK+ + PK +PE P K+ P + K V V V+LP+ E L Sbjct: 10054 EAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVP--VPVALPQEEEVLFEE 10111 Query: 4290 EVDIKG---PKVDIDAPDVDVHGPDWHLKMPK---VKMPKFSMPGFKGEGPDVDVTLPKA 4343 E+ + P+ + P+ + P+ +P+ + + +P + P+ + +P+ Sbjct: 10112 EIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPEE 10171 Query: 4344 DI--EISGPKVDIDAPDVSIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDFNLKGPKVKG 4401 ++ E+ PKV + AP I+ K+ K +P+ +AP +P++ PK Sbjct: 10172 EVLPEVK-PKVPVPAPVPEIK---KKVTEKKVVIPKKE-EAPPAKVPEV------PKKVE 10220 Query: 4402 DVDVSLPKVEGDLKGPEIDIKGPSLDIDTPDVNIEGP---EGKLKGPKFKMPEMNIKA-P 4457 + + LPK E ++ E+ + I ++ E P E + P ++PE+ KA P Sbjct: 10221 EKRIILPKEE-EVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPP-RVPEVIKKAVP 10278 Query: 4458 KISMPDFDLHLKGPKVKGDVDVSLPKVESDLKGPEVDIEGPEGKLKGPKFKMPDVHFKSP 4517 + P PK V P + K PE + P K + P K+P+V K P Sbjct: 10279 EAPTPV-------PK-----KVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVP 10326 Query: 4518 QISMSDIDLNLKGPKIKG----DMDISVPKLEGDLKGPKVDVKGPKVGIDT--PDIDIHG 4571 + + + P KG + +SV + + +++++ + ++ + + H Sbjct: 10327 EKKVL-VPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHE 10385 Query: 4572 PEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKVKGDMDIS----LPKVEGDLKGPEV 4627 E + +F + +K + + E K +V + K + KGPE+ Sbjct: 10386 VEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEI 10445 Query: 4628 D--IRDPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADIDVSG 4685 I PK P V + K+P+V PK + K P+ + +P + Sbjct: 10446 SEKIIPPKKP---PTKVVPRKEPPAKVPEV--PKKIVVEEKVRVPE-EPRVPPTKVPEVL 10499 Query: 4686 PKVDVDVPDVNIEGPDAKL-KGPKFKMPEMSIKAPKISMPDIDLNLKGPKVKGDVDVTLP 4744 P +V VP+ + P AK + P K+PE APK +P+ + + PK +P Sbjct: 10500 PPKEV-VPEKKVPVPPAKKPEAPPPKVPE----APKEVVPEKKVPVPPPKKPEVPPTKVP 10554 Query: 4745 KVEGDLKGPEADIKGPKVDINTPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVD-VS 4803 +V P+A + KV P P + PK +P+ +P + P+V V Sbjct: 10555 EV------PKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVK 10608 Query: 4804 LPKADIDVSGPKVDVDIPDVNIEGPDAKLKGPKFKMPEINIKAPKISIPDVDLDLKGPKV 4863 +P+A +V P+ V +P P K + P K+PE+ PK+++P+ + P Sbjct: 10609 VPEAPKEVV-PEKKVPVP------PPKKPEVPPTKVPEV----PKVAVPEKKVPEAIP-- 10655 Query: 4864 KGDFDVSVPKVEGTLKGPEVDLKGPRLDFEGPDAKL-SGPSLKMPSLEISAPKVTAPDVD 4922 PK E PEV + + E P A++ P P PK P+ Sbjct: 10656 --------PKPESP--PPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEK- 10704 Query: 4923 LHLKAPKIGFSGPKLEGGEVDLKGPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKFGF 4982 KAP + P+L +V + PK P V + P E P K+P+ PK Sbjct: 10705 ---KAPAVVAKKPELPPVKVP-EVPKEVVPEKKVPLVVPK-KPEAPPAKVPEV--PKEVV 10757 Query: 4983 GAKS---PKADIKSPSLDVTVPEAELNLETPEISVGGKGKKSKFKMPKIHMSGPKIKAKK 5039 K PK P+ VP+ + E P + V ++++ P+++ +I ++ Sbjct: 10758 PEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVP---ERAESPPPEVYEEPEEIAPEE 10814 Query: 5040 Q---GFDLNVPGGEIDASLKAPDVDVNIAGPDAALKV--DVKSPKTKKTMFGKMYFPDVE 5094 + + VP E + P A P+ K+ + K P KK P+ E Sbjct: 10815 EIAPEEEKPVPVAEEEEPEVPPP-----AVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPE 10869 Query: 5095 FDIKSPKFKAEAPLPSPKLEGELQAPDLELSLPAIHVEGLDIKAKAPK------VKMPDV 5148 I+ PK K P P P E + L AI + + K + P+ +K+P Sbjct: 10870 KVIEKPKLKPRPPPPPPAPPKE-DVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGG 10928 Query: 5149 DISVPKIEGDLK-GPKVQANLGA----------PDINIEGLDAKVKTPSFGISAP----- 5192 + V K+ + K PK + L + P + + L+ KVK P+ P Sbjct: 10929 EKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLE-KVKKPAVPEPPPPKPVE 10987 Query: 5193 QVSIPDVNVNLKGPKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGG- 5251 +V +P V + VP + P + L PE K K P+ + I P V+ E Sbjct: 10988 EVEVPTVTKRERKIPEPTKVPEI---KPAIPLPAPEPKPK-PEAEVKTIKPPPVEPEPTP 11043 Query: 5252 -GAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPS 5289 A V + + + + P + P +KG PS Sbjct: 11044 IAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPS 11082 Score = 84.3 bits (207), Expect = 3e-15 Identities = 321/1466 (21%), Positives = 571/1466 (38%), Gaps = 222/1466 (15%) Query: 1541 VSGPKVDIDVPDVNLEAPEGKLKGPKFKMPSMNIQTHKISMPDVGLNLKAPKLKTDVDVS 1600 ++ P+ I V V E K K P K+ + K+ +P + LK P K + Sbjct: 9786 ITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVP-IPKKLKPPPPKVPEE-- 9842 Query: 1601 LPKVEGDLKGPEIDVKAPKMDVNVGDIDIE-GPEGKLKGPKFKMPEMHFKAPKISMPDVD 1659 PK + K K K V + P+ + K +P AP + +P+V Sbjct: 9843 -PKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEV-APPVRVPEVP 9900 Query: 1660 LHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKVDIDAPDVEVHDPDWHLKMPKMKMPK 1719 L+ +V + +V E ++ + I + I +V P ++P+ +P+ Sbjct: 9901 KELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPE 9960 Query: 1720 FSMP---GFKAEGPEVDV----NLPKADIDVSGPSVDTDAPDLDIEGPEGKLKGSKFKMP 1772 P K E P V P+ + V P + P E P+ + K +P Sbjct: 9961 EKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVP 10020 Query: 1773 -KLNIKAPKVSMPDVDLNLKGPKLKGEIDASVPELEGDLRGPQVDVKGPFVEAEVPDVDL 1831 ++AP +P+V PK VPE + + P+ V+ P A+VP+V Sbjct: 10021 VPKKVEAPPAKVPEV------PK------KPVPEKKVPVPAPK-KVEAP--PAKVPEVPK 10065 Query: 1832 EC-PDAK--------LKGPKFKMPEMHFKAP-KISMPDVDLHLKGPKVKGDADVSVPKLE 1881 + P+ K ++ P K+P+ P +++P + L ++ + +V +P+ E Sbjct: 10066 KLIPEEKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEV-LPEEE 10124 Query: 1882 GDLTGPSVGVEVPDVELECPDAKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDVD 1941 L P +P+ E P+ + P+ + + +P+ + + +V +V Sbjct: 10125 EVL--PEEEEVLPEEEEVLPEEEEIPPE----EEEVPPEEEYVPEEEEFVPEEEVLPEVK 10178 Query: 1942 VSVPKLEGDLTGPSVGVEVPDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVDLHLKGP 2001 VP V VP+++ + + K+ PK K K P++ + + P Sbjct: 10179 PKVP----------VPAPVPEIKKKVTEKKVVIPK-KEEAPPAKVPEVPKKVEEKRIILP 10227 Query: 2002 KVKGDMDVSVPKVEGEMKVPDVDIKGPKMDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGF 2061 K + + V V + E + + +I P+ +V+ P ++P++ Sbjct: 10228 KEEEVLPVEVTEEPEEEPISEEEI--PEEPPSIEEVEEVAPP---RVPEV---------I 10273 Query: 2062 KAEGPEVDVNLPKADVVVSGPKVDVEVPDVSLEGPEGKLKGPKLKMPEMHFKAP--KISM 2119 K PE +PK V KV ++P+ + P K + P K+PE+ K P K+ + Sbjct: 10274 KKAVPEAPTPVPKK-VEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLV 10332 Query: 2120 PDVDLHLKGPKVKG----DVDVSLPKLEGDLTGPSVDVEVPDVELE-CPDAKLKGPKFKM 2174 P + P KG + VS+ + + +++EV + E+E P+ + +F Sbjct: 10333 PKKEAV---PPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEE----EFHE 10385 Query: 2175 PEMHFKTPKISMPDVNLNLKGPKVKGDMDVS-VPKVEGEMKVPDVDIRGPKVDIDAPDVD 2233 E +F+ + + + L+ +V+ + V V +V + +V++ + P Sbjct: 10386 VEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEV------FEKPKAP 10439 Query: 2234 VHGPDWHLKM-PKMKMPKFSMPGFKGEGPEVDVNLPKADVDVSGPKVDVEVPDVSLEGPE 2292 GP+ K+ P K P +P + E P +PK V +V E + PE Sbjct: 10440 PKGPEISEKIIPPKKPPTKVVP--RKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPE 10497 Query: 2293 GKLKGPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVDVSAPKLEGELKGPELDVKGPK 2352 + PK +PE P P+ PK+ P+ + + P+ P Sbjct: 10498 --VLPPKEVVPEKKVPVPPAKKPEAP----PPKVPEAPKEVVPEKKVPVPPPKKPEVPPT 10551 Query: 2353 LDADMPEVAV------EGPNGKWKTPKFKMPDMHFKAPKISMPDLDLHLKSPKAKGEVDV 2406 ++P+ AV E K ++P ++P+ APK +P+ + PK V Sbjct: 10552 KVPEVPKAAVPEKKVPEAIPPKPESPPPEVPE----APKEVVPEKKVPAAPPKKPEVTPV 10607 Query: 2407 DVPKLEGDLKGPHVDVSGPDIDIEGPEGKLKGPKFKMPDMHFKAPNISMPDVDLNLKGPK 2466 VP+ ++ P V P P K + P K+P++ P +++P+ K P+ Sbjct: 10608 KVPEAPKEVV-PEKKVPVP------PPKKPEVPPTKVPEV----PKVAVPEK----KVPE 10652 Query: 2467 -IKGDVDVSVPEV-----EGKLEVPDMNIRGPKVDVNAPDVQAPDWHLKMPKMKMPKFSM 2520 I + PEV E LE P + V P+ AP PK +P+ Sbjct: 10653 AIPPKPESPPPEVFEEPEEVALEEPPAEV------VEEPEPAAPPQVTVPPKKPVPEKKA 10706 Query: 2521 PGFKAEGPEVD-VNLPKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPKI 2579 P A+ PE+ V +P+ PK + V + P+ K + P K+PE+ PK Sbjct: 10707 PAVVAKKPELPPVKVPEV------PKEVVPEKKVPLVVPK-KPEAPPAKVPEV----PKE 10755 Query: 2580 SMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKMP 2639 +P+ + + PK +P+V P+ + K + P+ P + P Sbjct: 10756 VVPEKKVAV--PKKPEVPPAKVPEV------PKKPVLEEKPAVPVPERAESPPPEVYEEP 10807 Query: 2640 KVKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKLKGPKFKMPE 2699 + P+ + P+ + +P A+ E P+V P + PK +PE Sbjct: 10808 EEIAPEEEI------APEEEKPVPVAEE---------EEPEVP---PPAVPEEPKKIIPE 10849 Query: 2700 MNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHG 2759 K P I P+ P K P+ E ++ P++ + P P DV Sbjct: 10850 K--KVPVIKKPE------APPPKE------PEPEKVIEKPKLKPRPPPPPPAPPKEDVKE 10895 Query: 2760 PDWHLK-MPKIKMP-------KISMPGFKGEGPDVDVN--LPKADIDVSGPKVDVECPDV 2809 + LK +PK K+P K+ + K G + V LP+ + PK +V V Sbjct: 10896 KIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPE---PKEEVVLKSV 10952 Query: 2810 NIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDVDV-TGPKVEGDLKGPE 2868 + PE + PK + P+ K K ++P+ PK +V+V T K E + P Sbjct: 10953 LRKRPEEE--EPKVE-PKKLEKVKKPAVPEPP----PPKPVEEVEVPTVTKRERKIPEPT 11005 Query: 2869 VDLKGPKVDIDVPDVNVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDVSGP 2928 K P++ P + + P+ K P+ ++ P + PE V V G Sbjct: 11006 ---KVPEIK---PAIPLPAPEPKPK-PEAEVKTIKPPPVE---PEPTPIAAPVTVPVVGK 11055 Query: 2929 KVDVEGPDVNIEGPEGKLKGPKFKMP 2954 K + + P P+G +KG K P Sbjct: 11056 KAEAKAPKEEAAKPKGPIKGVPKKTP 11081 Score = 83.2 bits (204), Expect = 7e-15 Identities = 333/1467 (22%), Positives = 563/1467 (38%), Gaps = 255/1467 (17%) Query: 747 LKMPKMKMPKFSVPGFKAEGPEVDVNLPKADVDISGPKIDVTAPDVSIE-EPEGKLKGPK 805 LK P K+P+ F+ + + +++ K + K VT P + +P+ + K Sbjct: 9832 LKPPPPKVPEEPKKVFEEK---IRISITKRE------KEQVTEPAAKVPMKPKRVVAEEK 9882 Query: 806 FKMPEMNIKVPKISMPDVDLHLKGPNVKGEYDVTMPK----VESEIKVPDVELKSAKMDI 861 +P + P + +P+V L+ V E +V VE E + E + + Sbjct: 9883 VPVPRKEV-APPVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEE 9941 Query: 862 DVPDVEVQGPDWHLK-MPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVGVEVPDV 920 VP + V+ P+ K +P+ K P +P K P +PK + KV V +P Sbjct: 9942 VVPVIPVKVPEVPRKPVPEEKKP-VPVPKKKEAPPAKVPEVPKKPEE----KVPVLIPK- 9995 Query: 921 NIEGPEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGPKVKGEYDMTVPKL-EGDLKGPK 979 K K P K+PE+ PK +P+ + + PK VP++ + + K Sbjct: 9996 -------KEKPPPAKVPEV----PKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKK 10044 Query: 980 VDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGPEFDVNLSKANVDISAPKVDTNAP 1039 V V AP +++ P K+P++ PK +P K P PK Sbjct: 10045 VPVPAPK-KVEAPP--AKVPEV--PKKLIPEEKKPTP--------------VPK------ 10079 Query: 1040 DLSLEGPEGKLKGPKFKMPEMHFRAP-KMSLPDVDLDLKGPKMKGNVDISAPKIEGEMQV 1098 K++ P K+P+ P ++LP + L ++ ++ E E + Sbjct: 10080 ---------KVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLP---EEEEVL 10127 Query: 1099 PDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLKGEGPEVDVNLPKADVVVS 1158 P+ + P+ + P+ E +IP + +P + PE + +P+ +V+ Sbjct: 10128 PEEEEVLPEEEEVLPEEE--------EIPPEEE---EVPPEEEYVPEEEEFVPEEEVLPE 10176 Query: 1159 -GPKVDIEAP--DVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVKGDVDV 1215 PKV + AP ++ + E K+ PK K K P++ + + PK + + V Sbjct: 10177 VKPKVPVPAPVPEIKKKVTEKKVVIPK-KEEAPPAKVPEVPKKVEEKRIILPKEEEVLPV 10235 Query: 1216 SVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMPKFSMPGFKGEGREVD 1275 V + E + + EI P+ +VE P ++ K +P+ P K Sbjct: 10236 EVTEEPEEEPISEEEI--PEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPK------K 10287 Query: 1276 VNLPKADIDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLNLKG- 1334 V P A + P+ V VP E P K+ K+PE PK + KG Sbjct: 10288 VEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPK---KEAVPPAKGR 10344 Query: 1335 PKLKGDVDVSLPEVEGEMKVPDVDIKGPKVDISAPDVDVHGPDWHLKMPKVKMPKFSMPG 1394 L+ V V+ + + ++++ +V+ + + H + + + Sbjct: 10345 TVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFE------------- 10391 Query: 1395 FKGEGPEVD--VKLPKADVDVSG---------PKMDAEVPDVNIEGPDAKLKGPKFKMPE 1443 +GE EV+ +KL + V+ +AE +V E P A KGP ++ E Sbjct: 10392 -EGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEV-FEKPKAPPKGP--EISE 10447 Query: 1444 MSIKPQKISIPDVGLHLKGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKVDINAPDVEVHG 1503 I P+K P K VP+ E K P+V PK + V V Sbjct: 10448 KIIPPKK------------PPTK-----VVPRKEPPAKVPEV----PKKIVVEEKVRV-- 10484 Query: 1504 PDWHLKMPKVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPDVNLE-APEGKL 1562 P+ ++P K+P+ P K PE + +P A + P VP+ E PE K+ Sbjct: 10485 PE-EPRVPPTKVPEVLPP--KEVVPEKKVPVPPAKKPEAPPP---KVPEAPKEVVPEKKV 10538 Query: 1563 KGPKFKMPSMNIQTHKISMPDVGLNLKAPKLKTDVDVSLPKVEGDLKGPEIDVKAPKMDV 1622 P K P + +P+V KA + V ++P + + PE+ +APK V Sbjct: 10539 PVPPPKKP----EVPPTKVPEVP---KAAVPEKKVPEAIPP-KPESPPPEVP-EAPKEVV 10589 Query: 1623 NVGDIDIEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDMDVSVPKVE--- 1679 + P+ K + K+PE APK +P+ + + PK VP+V Sbjct: 10590 PEKKVPAAPPK-KPEVTPVKVPE----APKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVA 10644 Query: 1680 -GEMKVPDVDIKGPKVDIDAPDVEVHDPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPK 1738 E KVP+ PK + P+V + L+ P ++ + P A P+V V K Sbjct: 10645 VPEKKVPEA--IPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEP---AAPPQVTVPPKK 10699 Query: 1739 ADIDVSGPSVDTDAPDLDIEGPEGKLKGSKFKMPKLNIKAPKVSMPDVDLNLKGPKLKGE 1798 + P+V P+L K+P++ PK +P+ + L PK Sbjct: 10700 PVPEKKAPAVVAKKPEL-----------PPVKVPEV----PKEVVPEKKVPLVVPKKPEA 10744 Query: 1799 IDASVPELEGDLRGPQVDVKGPFVEAEVPDVDLECPDAKLKGPKFKMPEMHFKAPKISMP 1858 A VPE+ ++ VP+ + P K + P K+PE+ K P Sbjct: 10745 PPAKVPEVPKEV---------------VPEKKVAVP-KKPEVPPAKVPEVPKKPVLEEKP 10788 Query: 1859 DVDLHLKG----PKVKGDADVSVPKLEGDLTGPSVGVEVPDVELECPD----AKLKGPKF 1910 V + + P+V + + P+ E P VP E E P+ A + PK Sbjct: 10789 AVPVPERAESPPPEVYEEPEEIAPEEE---IAPEEEKPVPVAEEEEPEVPPPAVPEEPKK 10845 Query: 1911 KMPDMHFKAPKISMPDVDLHLKGPKVKGDVDVSVPKLEGDLTGPSVGVEVPDVELECPDA 1970 +P+ K P I P+ + + + + PKL+ P DV+ + Sbjct: 10846 IIPEK--KVPVIKKPEAP---PPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQL 10900 Query: 1971 KLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKM 2030 K PK K+PE K+ + + + KV+ + P+ + E+ + V K P Sbjct: 10901 KAI-PKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRP-- 10957 Query: 2031 DIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKAEGPEVDV-NLPKADVVVSGP-KVDVEV 2088 + + P V+ K+ K+K P P EV+V + K + + P KV Sbjct: 10958 EEEEPKVEPK------KLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIK 11011 Query: 2089 PDVSLEGPEGKLKGPKLKMPEMHFKAPKISMPDVDLHLKGPKVKGDVDVSLPKLEGDLTG 2148 P + L PE K K PE K +K P V+ + + + G Sbjct: 11012 PAIPLPAPEPKPK------PEAEVKT-----------IKPPPVEPEPTPIAAPVTVPVVG 11054 Query: 2149 PSVDVEVPDVELECPDAKLKGPKFKMP 2175 + + P E P +KG K P Sbjct: 11055 KKAEAKAPKEEAAKPKGPIKGVPKKTP 11081 Score = 78.6 bits (192), Expect = 2e-13 Identities = 233/1006 (23%), Positives = 398/1006 (39%), Gaps = 164/1006 (16%) Query: 3539 KAPKISMPDIDLNLKGPKVKGDVDISLPKLEGDLKGPEVDIKGPKVDINAPDVDVHGPDW 3598 +AP +P++ PK + I LPK E ++ EV + + I+ ++ P Sbjct: 10206 EAPPAKVPEV------PKKVEEKRIILPK-EEEVLPVEVTEEPEEEPISEEEIPEEPPSI 10258 Query: 3599 HLKMPKVKMPKFSMPGFKGEGPEVDVTLPKADIDISGPNVDVDVPDVNIEGPDAKLKGPK 3658 ++ +V P+ K PE +PK ++ V +P+ + P K + P Sbjct: 10259 E-EVEEVAPPRVPEV-IKKAVPEAPTPVPKK-VEAPPAKVSKKIPEEKVPVPVQKKEAPP 10315 Query: 3659 FKMPEMNIKAP--KISMPDFDLNLKGPKMKGDVVVSLPKVEGDLKGPEVDIKGPKVDIDT 3716 K+PE+ K P K+ +P + P KG V+ KV + EV +K +++++ Sbjct: 10316 AKVPEVPKKVPEKKVLVPKKE---AVPPAKGRTVLE-EKVSVAFR-QEVVVK-ERLELEV 10369 Query: 3717 PDINIE--GSEGKFKGPK--FKIPEMH--LKAPKISMPDIDLNLKGPKVKGDVDVSLPKM 3770 + +E E +F + F+ E H + K+ ++ + KV ++V + Sbjct: 10370 VEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEE 10429 Query: 3771 EGDLKGPEVDIKGPKVD------INAPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDV 3824 + P+ KGP++ P V + K+P+V PK + K P+ Sbjct: 10430 VEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEV--PKKIVVEEKVRVPEE 10487 Query: 3825 DVNLPKADLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKG 3884 P +V PK + V + P K + P K+PE APK +P+ + + Sbjct: 10488 PRVPPTKVPEVLPPKEVVPEKKVPVP-PAKKPEAPPPKVPE----APKEVVPEKKVPVPP 10542 Query: 3885 PKVKGDMDVSLPKVEGDMQVPDLDIKGPKVDINAPDVDVRGPDWHLKMPKIKMPKISMPG 3944 PK +P +VP + KV P P + PK +P+ +P Sbjct: 10543 PKKPEVPPTKVP------EVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPA 10596 Query: 3945 FKGEGPEV-DVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISM 4003 + PEV V +P+A +V P+ V VP P K + P K+PE+ PK+++ Sbjct: 10597 APPKKPEVTPVKVPEAPKEVV-PEKKVPVP------PPKKPEVPPTKVPEV----PKVAV 10645 Query: 4004 PDFDLHLKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKV 4063 P+ K + PK E PEV + +V ++ P +V V Sbjct: 10646 PE----------KKVPEAIPPKPES--PPPEVFEEPEEVALEEPPAEV-----------V 10682 Query: 4064 KMPKFSMPGFKGEGPEVDVNLPKADIDVSGPKVDIDTPDIDIHGPEGKLKGPKFKMPDLH 4123 + P+ + P P+V V K + P V P++ P K+P++ Sbjct: 10683 EEPEPAAP------PQVTVPPKKPVPEKKAPAVVAKKPEL-----------PPVKVPEV- 10724 Query: 4124 LKAPKISMPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPD 4183 PK +PE + L PK +P+V ++ PE + PK +VP V P+ Sbjct: 10725 ---PKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVV-PEKKVAVPKKP-EVPPAKV--PE 10777 Query: 4184 WHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADL---DVSGPKVDIDVPDVNIEGPD--- 4237 K + P +P + E P +V ++ + P+ + VP E P+ Sbjct: 10778 VPKKPVLEEKPAVPVPE-RAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPP 10836 Query: 4238 -AKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGP 4296 A + PK +PE K P I P+ P K P+ E ++ P++ + P Sbjct: 10837 PAVPEEPKKIIPEK--KVPVIKKPE------APPPKE------PEPEKVIEKPKLKPRPP 10882 Query: 4297 KVDIDAPDVDVHGPDWHLK-MPKVKMP-------KFSMPGFKGEGPDVDV--TLPKADIE 4346 P DV + LK +PK K+P K + K G + V LP+ E Sbjct: 10883 PPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPE 10942 Query: 4347 ISGPKVDIDAPDVSIEGPDAKLKGPKFKMPEM-NIKAPKISMPDIDFNLKGPKVKGDVDV 4405 PK ++ V + P+ + PK + ++ +K P + P P K +V Sbjct: 10943 ---PKEEVVLKSVLRKRPEE--EEPKVEPKKLEKVKKPAVPEP--------PPPKPVEEV 10989 Query: 4406 SLPKV-EGDLKGPEIDIKGPSLDIDTPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDF 4464 +P V + + K PE K P + P + + PE K PK + IK P + Sbjct: 10990 EVPTVTKRERKIPE-PTKVPEI---KPAIPLPAPEPK---PKPEAEVKTIKPPPVEP--- 11039 Query: 4465 DLHLKGPKVKGDVDVSLPKVESDLKGPEVDIEGPEGKLKGPKFKMP 4510 + + V V + +++ K P+ + P+G +KG K P Sbjct: 11040 ----EPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTP 11081 Score = 70.1 bits (170), Expect = 6e-11 Identities = 274/1312 (20%), Positives = 495/1312 (37%), Gaps = 212/1312 (16%) Query: 2825 MPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPEVDLKGP-KVDIDVPDV 2883 +P + K P++ + P+ K V V K K PEV K KV + +P Sbjct: 9943 VPVIPVKVPEVPRKPV------PEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKK 9996 Query: 2884 NVQGPDWHLKMPKMKMPKFSMP---GFKAEGPEVDV-NLPKADVDVSGPKVDVEGPDVNI 2939 P ++PK +P+ +P K E P V +PK V KV V P + Sbjct: 9997 EKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEK--KVPVPAPK-KV 10053 Query: 2940 EGPEGKL-KGPKFKMPEMNIKAP---KIPMPDFDLHLKGPKVKGDVDISLPKVEGDLKG- 2994 E P K+ + PK +PE P K+ P + K V V ++LP+ E L Sbjct: 10054 EAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVP--VPVALPQEEEVLFEE 10111 Query: 2995 ---PEVDIRGPQVDIDVPDVGVQGPDWHLKMPK---VKMPKFSMPGFKGEGPDVDVNLPK 3048 PE ++ P+ + +P+ P+ +P+ + + +P + P+ + +P+ Sbjct: 10112 EIVPEEEVL-PEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPE 10170 Query: 3049 AD-LDVSGPKVDID--VPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKV 3105 + L PKV + VP++ + E K+ PK + +AP +P++ PK Sbjct: 10171 EEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKE------EAPPAKVPEV------PKK 10218 Query: 3106 KGDMDVSLPKVEGDMKVPDVDIKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISMPGFKG 3165 + + LPK E + V +V + + I+ ++ + P ++ ++ P++ K Sbjct: 10219 VEEKRIILPKEEEVLPV-EVTEEPEEEPISEEEIPEEPPSIE-EVEEVAPPRVPEV-IKK 10275 Query: 3166 EGPEVDVNLPK------ADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKI 3219 PE +PK A + P+ V VP E P AK+ K+PE + PK Sbjct: 10276 AVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPKK 10335 Query: 3220 SMPDLDLNLKGPKMKG----EVDVSLANVEGDLKGPALDIKGPKIDVD--APDIDIHGPD 3273 P KG E VS+A + + L+++ + +V+ + + H + Sbjct: 10336 EAV--------PPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVE 10387 Query: 3274 AKLKGPKLKMPDMHVNMPKISMPEIDLNLKGSKLKGDVDVSGPKLEGDIKAPSLDIKGPE 3333 + + + + K+ ++ + K+ ++V + + P KGPE Sbjct: 10388 EYFEEGEFHEVEEFI---KLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPE 10444 Query: 3334 VD--VSGPKLNIEGKSKKSRFKLPKFNFSGSKVQTPEVDVKGKKPDIDITGPKVDINAPD 3391 + + PK K P +KV P + K P++ PK + Sbjct: 10445 ISEKIIPPK------------KPP------TKV-VPRKEPPAKVPEV----PKKIVVEEK 10481 Query: 3392 VEVQGKVKGSKFKMPFLSISSPKVSMPDVELNLKSPKVKGDLDIAGPNLEGDFKGPKVDI 3451 V V + + K+P + PK +P+ ++ + P + + PKV Sbjct: 10482 VRVPEEPRVPPTKVP--EVLPPKEVVPEKKVPVP------------PAKKPEAPPPKVPE 10527 Query: 3452 KAPEVNLNAPDVDVHGPDWNLKMPKMKMPKFSVSGLKAEGPDVAVDLPKGDINIEGPSMN 3511 EV P+ + +P K P+ P ++PK + Sbjct: 10528 APKEV----------VPEKKVPVPPPKKPEVP--------PTKVPEVPKAAV-------- 10561 Query: 3512 IEGPDLNVEGPEGGLKGPKFKMPDMNIKAPKISMPDIDLNLKGPKVKGDVDISLPKLEGD 3571 P+ V PE P+ P++ +APK +P+ + PK + +P Sbjct: 10562 ---PEKKV--PEAIPPKPESPPPEVP-EAPKEVVPEKKVPAAPPKKPEVTPVKVP----- 10610 Query: 3572 LKGPEVDIKGPKVDINAPDVDVHGPDWHLKMPKVKMPKFSMPGF---KGEGPEVDVTLPK 3628 + P+ + KV + P P ++PKV +P+ +P K E P +V Sbjct: 10611 -EAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEP 10669 Query: 3629 ADIDISGPNVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKA--------PKISMPDFDLNL 3680 ++ + P +V V + P PK +PE A P + +P+ + Sbjct: 10670 EEVALEEPPAEV-VEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEV 10728 Query: 3681 KGPKMKGDVVVSLPKVEGDLKGPEVDIKGPKVDIDTPDINIEGSEGKFKGPKFKIPEMHL 3740 P+ K +VV K PEV PK + + + K + P K+PE+ Sbjct: 10729 V-PEKKVPLVVPKKPEAPPAKVPEV----PKEVVPEKKVAV---PKKPEVPPAKVPEVPK 10780 Query: 3741 K-----APKISMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPEVDIKGPKVDINAPDVDV 3795 K P + +P+ P+V + + P+ E PE + P + P+V Sbjct: 10781 KPVLEEKPAVPVPE-RAESPPPEVYEEPEEIAPEEE---IAPEEEKPVPVAEEEEPEVP- 10835 Query: 3796 QGPDWHLKMPKVKMPKFSMPGFK------GEGPDVDVNLPKADLDVSGPKVDIDVPDVNI 3849 P + PK +P+ +P K + P+ + + K L P P ++ Sbjct: 10836 --PPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDV 10893 Query: 3850 EGPEGKLKG-PKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMQVPDLD 3908 + +LK PK K+PE K+ + + + KV+ + P+ + ++ + + Sbjct: 10894 KEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVL 10953 Query: 3909 IKGPKVDINAPDVDVRGPDWHLKMPKIKMPKISMPGFKGEGPEVDV-NLPKADLDVSGP- 3966 K P+ + P V+ + K+ K+K P + P EV+V + K + + P Sbjct: 10954 RKRPEEE--EPKVEPK------KLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPT 11005 Query: 3967 KVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKM 4026 KV P + + P+ K K PE +K +K P V+ + + Sbjct: 11006 KVPEIKPAIPLPAPEPKPK------PEAEVKT-----------IKPPPVEPEPTPIAAPV 11048 Query: 4027 EGDLKAPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGP 4078 + + + K PK + P + G P + PG GE P Sbjct: 11049 TVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKP 11100 Score = 60.8 bits (146), Expect = 4e-08 Identities = 274/1258 (21%), Positives = 479/1258 (38%), Gaps = 197/1258 (15%) Query: 3405 MPFLSISSPKVSMPDVELNLKSPKVKGDLDIAGPNLEGDFKGPKVDIKAPE-VNLNAPDV 3463 +P + + P+V V P+ K + + K P+V K E V + P Sbjct: 9943 VPVIPVKVPEVPRKPV------PEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKK 9996 Query: 3464 DVHGPDWNLKMPKMKMPKFSVS---GLKAEGPDVAV-DLPKGDINIEGPSMNIEGP-DLN 3518 + P ++PK +P+ V K E P V ++PK + P + P Sbjct: 9997 EKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKPV----PEKKVPVPAPKK 10052 Query: 3519 VEGPEGGL-KGPKFKMPDMNIKAP---KISMPDIDLNLKGPKVKGDVDISLPKLEGDLKG 3574 VE P + + PK +P+ P K+ P + K V V ++LP+ E L Sbjct: 10053 VEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKREPVP--VPVALPQEEEVLFE 10110 Query: 3575 ----PEVDIKGPKVDINAPDVDVHGPDWHLKMPKVKMP--KFSMPGFKGEGPEVDVTLPK 3628 PE ++ + ++ + +V + + + ++P + +P + PE + +P+ Sbjct: 10111 EEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPE 10170 Query: 3629 ADI--DISGPNVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLNLKGPKMK 3686 ++ ++ P V V P I+ K+ K +P+ +AP +P+ PK Sbjct: 10171 EEVLPEVK-PKVPVPAPVPEIK---KKVTEKKVVIPKKE-EAPPAKVPEV------PKKV 10219 Query: 3687 GDVVVSLPKVEGDL------KGPEVDIKGPKVDIDTPDINIEGSEGKFKGP---KFKIPE 3737 + + LPK E L + E I ++ + P I + P K +PE Sbjct: 10220 EEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPE 10279 Query: 3738 MHLKAPK-ISMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPEVDIKGPKVDINAPDVDVQ 3796 PK + P ++ K P+ K V V K K PEV K P+ + P + Sbjct: 10280 APTPVPKKVEAPPAKVSKKIPEEKVPVPVQ-KKEAPPAKVPEVPKKVPEKKVLVPKKEAV 10338 Query: 3797 GPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPEGKL 3856 P K V K S+ F+ E V + +L+V +V+ + E Sbjct: 10339 PP---AKGRTVLEEKVSV-AFRQEV----VVKERLELEVVEAEVEEIPEEEEFHEVEEYF 10390 Query: 3857 KGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMQVPDLDIKGPKVDI 3916 + +F E IK + ++ + KV ++V + + P KGP +I Sbjct: 10391 EEGEFHEVEEFIK---LEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGP--EI 10445 Query: 3917 NAPDVDVRGPDWHL---KMPKIKMPKISMPGFKGEGPEV--DVNLPKADLDVSGPKVDVD 3971 + + + P + K P K+P++ E V + +P + P +V Sbjct: 10446 SEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEV- 10504 Query: 3972 VPDVNIEGPDAKL-KGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKMEGDL 4030 VP+ + P AK + P K+PE APK +P+ + + PK +P++ Sbjct: 10505 VPEKKVPVPPAKKPEAPPPKVPE----APKEVVPEKKVPVPPPKKPEVPPTKVPEV---- 10556 Query: 4031 KAPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVD-VNLPKADI 4089 P+ + KV P P + PK +P+ +P + PEV V +P+A Sbjct: 10557 --PKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPK 10614 Query: 4090 DVSGPKVDIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKISMPEVDLNLKGPKMKGDVDV 4149 +V P+ + P P K + P K+P++ PK+++PE + P Sbjct: 10615 EVV-PEKKVPVP------PPKKPEVPPTKVPEV----PKVAVPEKKVPEAIPPKPES--- 10660 Query: 4150 SLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVD 4209 P E + EV ++ P ++ V + + P PK +P+ P + P++ Sbjct: 10661 --PPPEVFEEPEEVALEEPPAEV-VEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELP 10717 Query: 4210 -VNLPKADLDV-SGPKVDIDVPDVNIEGPDAKL-KGPKFKMPEMNIKAPKISMPDFDLHL 4266 V +P+ +V KV + VP E P AK+ + PK +PE + PK Sbjct: 10718 PVKVPEVPKEVVPEKKVPLVVPK-KPEAPPAKVPEVPKEVVPEKKVAVPK---------- 10766 Query: 4267 KGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSM 4326 P+V +P+V P+ + K + P+ P + P+ P+ + Sbjct: 10767 -KPEVP---PAKVPEV------PKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEI 10816 Query: 4327 PGFKGEGPDVDVTLPKADIEISGPKVDIDAPDVSIEGPDAKLKGPKFKMPEMNIKAPKIS 4386 P+ + +P A+ E P+V P A + PK +PE K P I Sbjct: 10817 ------APEEEKPVPVAEEE---------EPEVP---PPAVPEEPKKIIPEK--KVPVIK 10856 Query: 4387 MPDIDFNLKGPKVKGDVDVSLPKVEGDLKGPEIDIKGPSLDIDTPDVNIEGPEGKLKG-P 4445 P+ P K P+ E ++ P++ + P P +++ +LK P Sbjct: 10857 KPE------APPPKE------PEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIP 10904 Query: 4446 KFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVESDL-------KGPEVDIEGP 4498 K K+PE K+ + + KV+ + P+ + ++ K PE + Sbjct: 10905 KKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKV 10964 Query: 4499 EGKLKGPKFKMPDVHFKSPQISMSDIDLNL------------KGPKIKGDMDISVP---- 4542 E K K K K P V P + ++++ K P+IK + + P Sbjct: 10965 EPK-KLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKP 11023 Query: 4543 KLEGDLKGPK----------------VDVKGPKVGIDTPDIDIHGPEGKLKGPKFKMP 4584 K E ++K K V V G K P + P+G +KG K P Sbjct: 11024 KPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTP 11081 Score = 42.0 bits (97), Expect = 0.018 Identities = 212/1006 (21%), Positives = 374/1006 (37%), Gaps = 175/1006 (17%) Query: 4347 ISGPKVDIDAPDVSIEGPDAKLKGPKFKMPEMNIKAPKISMPDIDFNLKGPKVKGDVDVS 4406 I+ P+ I V E K K P K+ + + K+ +P I LK P K + Sbjct: 9786 ITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVP-IPKKLKPPPPKVPEE-- 9842 Query: 4407 LPKVEGDLKGPEIDIKGPSLDIDTPDVNIE-GPEGKLKGPKFKMPEMNIKAPKISMPDFD 4465 PK + K K + P + P+ + K +P + AP + +P+ Sbjct: 9843 -PKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEV-APPVRVPEVP 9900 Query: 4466 LHLKGPKVKGDVDVSLPKVESDLKGPEVDIEGPEGKLKGPKFKMPDVHFKSPQISMSDID 4525 L+ +V + +V + VE L E + E + + +P + K P++ + Sbjct: 9901 KELEPEEVAFEEEV-VTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPV- 9958 Query: 4526 LNLKGPKIKGDMDISVPKLEGDLKGPKVDVKGP-KVGIDTPDIDIHGPEGKLKGPKFKMP 4584 P+ K + + K K P+V K KV + P K K P K+P Sbjct: 9959 -----PEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPK--------KEKPPPAKVP 10005 Query: 4585 DLHLKAPKISMPEVDLNLKGPKVKGDMDISLPKVEGDLKGPEVDIRDPKVDIDVPDVDVQ 4644 ++ PK +PE + + PK +P+V P+ + + KV + P V+ Sbjct: 10006 EV----PKKPVPEEKVPVPVPKKVEAPPAKVPEV------PKKPVPEKKVPVPAPK-KVE 10054 Query: 4645 GPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADIDVSGPKVDVDVPDVNIEGPDAKL 4704 P K+P+V PK +P K P +PK ++ PKV V + Sbjct: 10055 APP--AKVPEV--PKKLIPEEKKPTP-----VPKK-VEAPPPKVPKKREPVPV------- 10097 Query: 4705 KGPKFKMPEMSIKAPKISMPDIDLNLKGPKVKGDVDVTLPKVEGDLKGPEADIKGPKVDI 4764 P E + + +P+ ++ + +V + + LP+ E L PE + P+ + Sbjct: 10098 --PVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVL--PEEEEIPPEEE- 10152 Query: 4765 NTPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVSLPKADIDVSGPKVDVDIPDVN 4824 P + + P+ +P+ ++ +P K P V V P +I + V IP Sbjct: 10153 EVPPEEEYVPEEEEFVPEEEV----LPEVK---PKVPVPAPVPEIKKKVTEKKVVIPKKE 10205 Query: 4825 IEGPDAKLKGPKFKMPEINIKAPKIS---------------IPDVDLDLKGPKVKGDFDV 4869 E P AK+ K+ E I PK I + ++ + P ++ +V Sbjct: 10206 -EAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEV 10264 Query: 4870 SVPKVEGTLKG------------------------PEVDLKGPRLDFEGPDAKLSGPSLK 4905 + P+V +K PE + P E P AK+ K Sbjct: 10265 APPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKK 10324 Query: 4906 MPSLEISAPK-----------VTAPDVDLHLKAPKIGFSGPKLEGGEVDLKGPKVEAPSL 4954 +P ++ PK V V + + + +LE E +++ E P Sbjct: 10325 VPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVE----EIPEE 10380 Query: 4955 DVHMDSPDINIEGPDVKIPKFKKPKFGFGAKSPKADIKSPSLDVTVPEAELNLETPEISV 5014 + + + EG ++ +F K + + + + ++V E E+ V Sbjct: 10381 EEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEV--------FEAEEVEV 10432 Query: 5015 GGKGKKSKFKMPKIHMSGPKIKAK----KQGFDLNVPGGEIDASLKAPDVDVNIAGPD-A 5069 F+ PK GP+I K K+ VP E A K P+V I + Sbjct: 10433 --------FEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPA--KVPEVPKKIVVEEKV 10482 Query: 5070 ALKVDVKSPKTK--KTMFGKMYFPDVEFDIKSPKFKAEAPLPSPKLEGELQAPDLELSLP 5127 + + + P TK + + K P+ + + P K EAP P + P+ ++ +P Sbjct: 10483 RVPEEPRVPPTKVPEVLPPKEVVPEKKVPV-PPAKKPEAPPPKVPEAPKEVVPEKKVPVP 10541 Query: 5128 AIHVEGLDIKAKAPKVKMPDVDISVPKIEGDLKGPKVQANLGAPDINI-EGLDAKVKTPS 5186 K + P K+P+V PK P+ + E + K ++P Sbjct: 10542 P------PKKPEVPPTKVPEV-------------PKA----AVPEKKVPEAIPPKPESPP 10578 Query: 5187 FGI-SAPQVSIPDVNVNLKGPKIKGDVPSVGLEGPDVDLQGPEAKIKFP---KFSMPKIG 5242 + AP+ +P+ V PK P E P + PE K+ P K +P Sbjct: 10579 PEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVV--PEKKVPVPPPKKPEVPPTK 10636 Query: 5243 IPGV-KMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDL 5287 +P V K+ +V +P + + P+V E +V+L+ P ++ Sbjct: 10637 VPEVPKVAVPEKKVPEAIPP-KPESPPPEVFEEPEEVALEEPPAEV 10681 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 79.3 bits (194), Expect = 1e-13 Identities = 179/638 (28%), Positives = 231/638 (36%), Gaps = 104/638 (16%) Query: 5160 KGPKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPSVGLEG 5219 KG K QA P + G+ P F S + D+ L P +KGD +G G Sbjct: 514 KGEKGQAGATGPK-GLPGIPGAPGAPGFPGSKGEPG--DI---LTFPGMKGDKGELGSPG 567 Query: 5220 PD--VDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQ--------LPSLEGDLRGP 5269 L G + P G+PG K E GG + LP L G++ Sbjct: 568 APGLPGLPGTPGQDGLP-------GLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPM 620 Query: 5270 DVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGL 5329 GP + G+ + N P + GP D G ++ +P + Sbjct: 621 GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGD---PGQTITQPGKPGLPGNPGRDGDV 677 Query: 5330 NLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGA 5389 L G G G +PGI + K G P + L GP G G I P + G Sbjct: 678 GLPGDPGLPGQPG----LPGIPGS-KGEPGIPGIGLPGPP--GPKGFPG-IPGPPGAPGT 729 Query: 5390 PD-LSLEASEGSIKLPKMK-LPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRI 5447 P + LE G P K P F + P + P G L GP D GP Sbjct: 730 PGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGL----PGFKGAL-GPKGDRGFPGP-- 782 Query: 5448 SAPNVDFNLEG-PKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMP---------GI 5497 P L+G P KG +G G+ GP GLPGIGVQG G +P GI Sbjct: 783 PGPPGRTGLDGLPGPKGDVGPNGQ-PGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGI 841 Query: 5498 KSSGCDVNLPGVNVKLPTGQISGPEIKG-----------GL--KGSEVGFHGAAPDISVK 5544 D PG++V P G+ P I G GL K GF G ++ + Sbjct: 842 PGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMM 901 Query: 5545 GPAFNMASPESDFGINLKG--PKIKGGADVSGGVSAPDISLGEGHLSVKGSGGE-----W 5597 GP P GI + P +KG + G P G KGS GE Sbjct: 902 GP----PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLP------GPTGEKGSKGEPGLPGP 951 Query: 5598 KGPQVSSALNLDTSKFAGGL----HFSGPKVEGGVKG--GQIGLQA-PGL-SVSGPQGH- 5648 GP + L K GL SGPK G+ G GQ GL PGL GP+G+ Sbjct: 952 PGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNP 1011 Query: 5649 -LESGSGKVTFPKMK--IPKFTFSGRELVGREMGVDVHFPKAEASIQAGAGDGEWEESEV 5705 L G + P +K I F G + V G P S G+ + + Sbjct: 1012 GLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPS-GVPGQPGSPGLPGQKGDKGDPGI 1070 Query: 5706 KLKKSKIKMPKFNFSKPKGKGGVTGSP-EASISGSKGD 5742 S I +P PKG+ G+ G P I GS GD Sbjct: 1071 ----SSIGLP--GLPGPKGEPGLPGYPGNPGIKGSVGD 1102 Score = 65.5 bits (158), Expect = 2e-09 Identities = 229/925 (24%), Positives = 316/925 (34%), Gaps = 193/925 (20%) Query: 4663 PGFKGE-GPDVDVNLPKAD--------IDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPE 4713 PG G G D DV LP + G K + +P + + GP GPK Sbjct: 665 PGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPP----GPK----- 715 Query: 4714 MSIKAPKISMPDIDLNLKGPKVKGDVDVTLPKVEGDLKGPEADIKGPKVDINTPDVDVHG 4773 P I P G + + P GP+ + P + G Sbjct: 716 --------GFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGE----------PGFALPG 757 Query: 4774 PDWHLKMPKVKMPKFSMPGFKGE-GPDVDVSLP-------KADID-VSGPKVDVDIPDVN 4824 P +PGFKG GP D P + +D + GPK DV Sbjct: 758 PPGPP----------GLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV------ 801 Query: 4825 IEGPDAKLKGPKFK--MPEINIKAPKISIPDVDLDLKGPKVKGDFDVSVPKVEGTLKGPE 4882 GP+ + GP +P I ++ P P + G + P + G + G + Sbjct: 802 --GPNGQ-PGPMGPPGLPGIGVQGPP----------GPPGIPGP--IGQPGLHG-IPGEK 845 Query: 4883 VDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLHLKAPKIGFSGPKLEGGEV 4942 D P LD GP + P + I P L KA GF G K GE+ Sbjct: 846 GDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG----LPGKAGASGFPGTK---GEM 898 Query: 4943 DLKGPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKFGFGAKSPKADIKSPSLDVTVPE 5002 + GP L + S ++G D + P G K P L Sbjct: 899 GMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLP----GPTGEKGSKGEPGLPGPPGP 954 Query: 5003 AELNLETPEISVGGKGKKSKFKMPKIH-MSGPKIKAKKQGFDLNVPGGEIDASLKAPDVD 5061 + NL +G KG+K + +P I +SGPK G D PG L P Sbjct: 955 MDPNL------LGSKGEKGEPGLPGIPGVSGPKGYQGLPG-DPGQPGLSGQPGLPGPPGP 1007 Query: 5062 VNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEFDIKSPKFKAEAPLP--SPKLEGELQA 5119 P + + P K G M FP + ++ P + P SP L G+ Sbjct: 1008 KG--NPGLPGQPGLIGPPGLKGTIGDMGFPGPQ-GVEGPPGPSGVPGQPGSPGLPGQKG- 1063 Query: 5120 PDLELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGDLKGPKVQANLGAPDI----NI 5175 + P I GL P + P + +P G+ P ++ ++G P + Sbjct: 1064 ---DKGDPGISSIGL------PGLPGPKGEPGLPGYPGN---PGIKGSVGDPGLPGLPGT 1111 Query: 5176 EGLDAKVKTPSF----GISAPQ-VSIPDVNVNLKG----------------PKIKGDVPS 5214 G + P F G P+ +S P N L G P KG Sbjct: 1112 PGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQ 1171 Query: 5215 VGLEGPDVDLQGPEAKIKFPKFSMP-KIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKL 5273 G+ GP G + + P F P G+PG+ + G LP + G+ P K Sbjct: 1172 DGIPGP----AGQKGEPGQPGFGNPGPPGLPGLSGQKGDGG----LPGIPGNPGLPGPKG 1223 Query: 5274 EGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPG----L 5329 E PG P V GP GP+L+G P PG Sbjct: 1224 E--------PGFH------GFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPTGFQ 1269 Query: 5330 NLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRG-PSLQGDLA---VSGDIKCPKV 5385 L G G + G+G GI K N G P L G P L+GD + G+ P + Sbjct: 1270 GLPGPEGPPGLPGNG----GIKGE-KGNPGQPG--LPGLPGLKGDQGPPGLQGNPGRPGL 1322 Query: 5386 SVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGP 5445 + D L G P MK P PGS GP+ L GP L GP Sbjct: 1323 NGMKGDPGLPGVPG---FPGMKGPS---GVPGS------AGPEGEPGLIGPPGPPGLPGP 1370 Query: 5446 RISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPG-IGVQGLEGNLQMPGIKSSGCDV 5504 + + + P + G G G + GP GLPG G G G +PG +G Sbjct: 1371 SGQSIIIKGDAGPPGIPGQPGLKG-LPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRK 1429 Query: 5505 NLPGVNVKLPTGQISGPEIKGGLKG 5529 PG+ + T + GP GL+G Sbjct: 1430 GDPGLPGQPGTRGLDGPPGPDGLQG 1454 Score = 65.1 bits (157), Expect = 2e-09 Identities = 139/512 (27%), Positives = 179/512 (34%), Gaps = 110/512 (21%) Query: 5200 NVNLKG-PKIKGDVPSVGLEGPD-------VDLQGPEAKIKFPKFSMPK--IGIPGVKME 5249 N+ L G P KG+ G++GP + GP FP K G PG+ + Sbjct: 360 NIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIP 419 Query: 5250 GGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKG- 5308 G P L+G P L GP GP + PS + P GP KG Sbjct: 420 GP--------PGLDGQPGAPG--LPGPP-GPAGPHIP-PSDEICEPGPPGPPGSPGDKGL 467 Query: 5309 ---PSLKGD----------LDASVPSMKVHAPGL-------NLSGVGG-KMQVGGDGVK- 5346 +KGD S P + PGL G G K Q G G K Sbjct: 468 QGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKG 527 Query: 5347 VPGIDATTKL-----NVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDL-SLEASEGS 5400 +PGI + G P L P ++GD G++ P GAP L L + G Sbjct: 528 LPGIPGAPGAPGFPGSKGEPGDILTFPGMKGD---KGELGSP----GAPGLPGLPGTPGQ 580 Query: 5401 IKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAP---------- 5450 LP + P+ PG +GP + L G ++ GP P Sbjct: 581 DGLPGLPGPK---GEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQ 637 Query: 5451 NVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGI----------GVQGLEGNLQMPGIKSS 5500 V N P + G G G+ GLPG G GL G +PGI S Sbjct: 638 GVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGS 697 Query: 5501 GCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGIN 5560 + +PG+ + P G P I G G G I ++GP P Sbjct: 698 KGEPGIPGIGLPGPPGPKGFPGIPG-----PPGAPGTPGRIGLEGPPGPPGFP------- 745 Query: 5561 LKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFS 5620 GPK + G + G P + +G L KG G P LD GL Sbjct: 746 --GPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLD------GL--P 795 Query: 5621 GPKVEGGVKG-----GQIGLQAPGLSVSGPQG 5647 GPK + G G G GL PG+ V GP G Sbjct: 796 GPKGDVGPNGQPGPMGPPGL--PGIGVQGPPG 825 Score = 59.3 bits (142), Expect = 1e-07 Identities = 258/1047 (24%), Positives = 346/1047 (33%), Gaps = 196/1047 (18%) Query: 4664 GFKGEGPDVDVNLPKADIDVSGPKVDVDVPDVNIEGPDAKL--KGPKFKMPEMSIKAPKI 4721 G KG+ D N +SGP +P + GP L G K + + PK Sbjct: 472 GVKGDKGDTCFNC--IGTGISGPPGQPGLP--GLPGPPGSLGFPGQKGEKGQAGATGPK- 526 Query: 4722 SMPDIDLNLKGPKVKGDVDVTLPKVEGDLKGPEADI------KGPKVDINTPDVD----V 4771 +P I P G KG DI KG K ++ +P + Sbjct: 527 GLPGIPGAPGAPGFPGS------------KGEPGDILTFPGMKGDKGELGSPGAPGLPGL 574 Query: 4772 HGPDWHLKMPKVKMPKFSMPG--FKGE-GPDVDVSLPKADIDVS----------GPKVDV 4818 G +P + PK G FKGE GP + LP ++ GP + Sbjct: 575 PGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEK 634 Query: 4819 DIPDVNIEGPDAKLKGPKFKMPEINIKAPKISIP-----DVDLDLKG-PKVKGDFDVSVP 4872 I V + GPK + + K +P D D+ L G P + G +P Sbjct: 635 GIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQ--PGLP 692 Query: 4873 KVEGTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLHLKAPKIGF 4932 + G+ P + P + GP P + P P +IG Sbjct: 693 GIPGSKGEPGI----PGIGLPGPPGPKGFPGIPGPPGAPGTPG-------------RIGL 735 Query: 4933 SGPKLEGGEVDLKGPKVEAPSLDVHMDSPDINIEGPDVK--IPKFKKPKFGFGAKSPKAD 4990 GP G GPK E P + GP +P FK GA PK D Sbjct: 736 EGPP---GPPGFPGPKGE----------PGFALPGPPGPPGLPGFK------GALGPKGD 776 Query: 4991 IKSPSLDVTVPEAELN-LETPEISVGGKGKKSKFKMPKIHMSGPKIKAKKQGFDLNVPGG 5049 P L+ L P+ VG G+ P + P I + +PG Sbjct: 777 RGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGL----PGIGVQGPPGPPGIPGP 832 Query: 5050 EIDASLKAPDVDVNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEFDIKSPKFKAEAPLP 5109 L + GP +DV P ++ G P SP +A Sbjct: 833 IGQPGLHGIPGEKGDPGPPG---LDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS 889 Query: 5110 S-PKLEGEL-----QAPDLELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGDL--KG 5161 P +GE+ P L +P ++ P +K D P + G KG Sbjct: 890 GFPGTKGEMGMMGPPGPPGPLGIPG--------RSGVPGLKGDDGLQGQPGLPGPTGEKG 941 Query: 5162 PKVQANLGAP----DINIEGLDAKVKTPSF----GISAP-----------------QVSI 5196 K + L P D N+ G + P G+S P Q + Sbjct: 942 SKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGL 1001 Query: 5197 PDV-----NVNLKG-------PKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIP 5244 P N L G P +KG + +G GP ++GP P G+P Sbjct: 1002 PGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQ-GVEGPPGPSGVPG-QPGSPGLP 1059 Query: 5245 GVKMEGGGAEVHA-QLPSLEGDLRGPDVKLEGPDVSLKGPGVD--LPSVNLSMPKVSGPD 5301 G K + G + + LP L G P + + +KG D LP + + P Sbjct: 1060 GQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPG 1119 Query: 5302 LDLNLKGPSLKGDLDASVPSMKVHAPGLN--LSGVGGKMQVGGDGVK-VPGID-----AT 5353 L P G S P PG + G G Q G G K PG D A Sbjct: 1120 LPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAG 1179 Query: 5354 TKLNVGAPDVTLRGP-SLQGDLAVSGDIKCPKVSVGAPDLSLEASE-GSIKLPKMKLPQF 5411 K G P GP L G GD P + G P L E G P ++ P Sbjct: 1180 QKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIP-GNPGLPGPKGEPGFHGFPGVQGPPG 1238 Query: 5412 GISTPGSDLH--VNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPK-VKGSLGAT 5468 +PG L GPQ GP L GP EGP + G+ G Sbjct: 1239 PPGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGP-----------EGPPGLPGNGGIK 1287 Query: 5469 GEIKGPTVGG--GLPGI----GVQGLEGNLQMPGIKSSGCDVNLPGV----NVKLPTG-- 5516 GE P G GLPG+ G GL+GN PG+ D LPGV +K P+G Sbjct: 1288 GEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVP 1347 Query: 5517 QISGPEIKGGLKG--SEVGFHG-AAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVS 5573 +GPE + GL G G G + I +KG A P L GP +G + Sbjct: 1348 GSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGP--QGPQGLP 1405 Query: 5574 GGVSAPDISLGEGHLSVKGSGGEWKGP 5600 G P G G+GG P Sbjct: 1406 GPTGPPGDPGRNGLPGFDGAGGRKGDP 1432 Score = 55.5 bits (132), Expect = 2e-06 Identities = 142/508 (27%), Positives = 191/508 (37%), Gaps = 81/508 (15%) Query: 209 PSGSGAASPTGSAVDIRAGAISASGPELQGA-GHSKLQVTMPGIKVGGSGVNVNAKGLDL 267 P G G P G I+ A + P + G G +T PG K G G N G D+ Sbjct: 622 PPGFGPPGPVGEK-GIQGVAGNPGQPGIPGPKGDPGQTITQPG-KPGLPG-NPGRDG-DV 677 Query: 268 GGRGGVQVPAVDISSSLGGRAVEVQGPSLE-SGDHGKIKFPTMKVPKFGVSTGREGQTPK 326 G G +P + G E P + G G FP + P G G + Sbjct: 678 GLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPP-----GAPGTPGR 732 Query: 327 AGLRVSAPEVSVGHKG--GKPGLTIQAPQLEVSVPSANIEGLEGKLKGPQITGPSLEGDL 384 GL P G G G+PG + P +P G +G L GP +GD Sbjct: 733 IGLE--GPPGPPGFPGPKGEPGFALPGPPGPPGLP-----GFKGAL------GP--KGDR 777 Query: 385 GLKGAK-PQGHIGVDASAPQIGGSI-----TGPSVEVQAPDIDVQGPGSKLNVPKM--KV 436 G G P G G+D P G + GP P I VQGP +P + Sbjct: 778 GFPGPPGPPGRTGLDG-LPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQP 836 Query: 437 PKFSVSGAKGEE--TGIDVTLPTGE---VTVPGVSGDVSLPEIATGGLEGK-----MKGT 486 + G KG+ G+DV P GE +PG G + P + GL GK GT Sbjct: 837 GLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPP--GSPGLPGKAGASGFPGT 894 Query: 487 KVKTPEMIIQKPKISMQDVDLSLGSPKLKGDIKVSAPGVQGD--VKGPQVALKGSRVDIE 544 K + M P + + G P LKGD G+QG + GP KGS+ + Sbjct: 895 KGEMGMMGPPGPPGPL-GIPGRSGVPGLKGD-----DGLQGQPGLPGP-TGEKGSKGEPG 947 Query: 545 TPNLEGTLTGPRLGS--PSGKTGTCRISMSEVDLNVAAPKVKGGV--DVTLPRVEGKVKV 600 P G + LGS G+ G I V+ PK G+ D P + G+ + Sbjct: 948 LPGPPGPMDPNLLGSKGEKGEPGLPGIP------GVSGPKGYQGLPGDPGQPGLSGQPGL 1001 Query: 601 PEVDVRGPKVDVSAPDVEAHGPEWNLKMPKMK--MPTFSTPGAKG-EGPDVHMTLP--KG 655 P GPK + P G + P +K + PG +G EGP +P G Sbjct: 1002 P--GPPGPKGNPGLP-----GQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPG 1054 Query: 656 DISISGPKVNVEAPDVNLEGLGGKLKGP 683 + G K + P ++ GL G L GP Sbjct: 1055 SPGLPGQKGDKGDPGISSIGLPG-LPGP 1081 Score = 54.3 bits (129), Expect = 4e-06 Identities = 224/889 (25%), Positives = 316/889 (35%), Gaps = 167/889 (18%) Query: 2489 IRGPKVDVNAPDVQAPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDI 2548 ++GP P ++ + M + PK + PG+ GP LP I GP + Sbjct: 142 LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGN-PGYP--GPPGIQGLP-GPTGIPGP-IGP 196 Query: 2549 EGPDVNIEGPEGK--LKGPKLKMPEMNIKAPKISMPDFDLHLKGP--------KVKGDVD 2598 GP + GP G L GPK M +N + PK + L +GP + K +D Sbjct: 197 PGPP-GLMGPPGPPGLPGPKGNMG-LNFQGPKGEKGEQGL--QGPPGPPGQISEQKRPID 252 Query: 2599 VSLPKVEGDLKG---------------PEVDIKGPKVDINAPDV-GVQGPDWHLKMPKVK 2642 V K + L G P KG K + P G G D P + Sbjct: 253 VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312 Query: 2643 -MPKFSMPGFKGE-GPDGDVKLPKADIDVSGPK-VDIEGPDVNIE-GPEGKLKGPKFKMP 2698 +P PG+ GE G DG+ K K D GP + I P I G +G + P Sbjct: 313 GLP--GDPGYPGEPGRDGE-KGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE 369 Query: 2699 EMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPK-------VEGDLKGPEVDIKGPK-VDI 2750 + P I P L GP + P +GD P + I GP +D Sbjct: 370 KGERGFPGIQGPP---GLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG 426 Query: 2751 DAPDVDVHGPDWHLKMPKIKMPKISMPGFKGE-GPDVDVNLPKADIDVSGPKVDV--ECP 2807 + GP +I PG G G D L + + V G K D C Sbjct: 427 QPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGL-QGEQGVKGDKGDTCFNCI 485 Query: 2808 DVNIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPK-IKGDVDVTGPKVEGDLKG 2866 I GP G+ P P P TGPK + G G KG Sbjct: 486 GTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKG 545 Query: 2867 PEVDL------KGPKVDIDVPDV----NVQGPDWHLKMPKMKMPKFSMPG--FKAE-GPE 2913 D+ KG K ++ P + G +P + PK G FK E GP Sbjct: 546 EPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPP 605 Query: 2914 VDVNLPKADVDVSG---PKVDVEGP--DVNIEGPEGK-----LKGPKFKMPEMNIKAPKI 2963 + LP ++ P GP + I+G G + GPK P I P Sbjct: 606 GNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGD-PGQTITQPGK 664 Query: 2964 P-MP-----DFDLHLKG-PKVKGDVDI-SLPKVEGDLKGPEVDIRGPQVDIDVPDV---- 3011 P +P D D+ L G P + G + +P +G+ P + + GP P + Sbjct: 665 PGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPP 724 Query: 3012 ---------GVQGPDWHLKMPKVK-MPKFSMPG---------FKGE-GPDVDVNLP---- 3047 G++GP P K P F++PG FKG GP D P Sbjct: 725 GAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPG 784 Query: 3048 ---KADLD-VSGPKVDIDVPDVNIEGPEGKLKGPKFK--MPEMNIKAPKISMPDIDLNLK 3101 + LD + GPK D+ GP G+ GP +P + ++ P P I + Sbjct: 785 PPGRTGLDGLPGPKGDV--------GPNGQ-PGPMGPPGLPGIGVQGPP-GPPGIPGPIG 834 Query: 3102 GPKVKGDMDVSLPKVEGDMKVPDVDIKGPKVDINAPDV-DVQGPDWHLKMPKI--KMPKI 3158 P + G +P +GD P +D+ GP + +P + GP P + K Sbjct: 835 QPGLHG-----IPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS 889 Query: 3159 SMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPK 3218 PG KGE + P L + G VP ++G D L+G P Sbjct: 890 GFPGTKGEMGMMGPPGPPGPLGIPGRS---GVP--GLKGDDG-LQG-----------QPG 932 Query: 3219 ISMPDLDLNLKG----PKMKGEVDVSLANVEGDLKGPAL----DIKGPK 3259 + P + KG P G +D +L +G+ P L + GPK Sbjct: 933 LPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPK 981 Score = 51.2 bits (121), Expect = 3e-05 Identities = 199/836 (23%), Positives = 285/836 (34%), Gaps = 207/836 (24%) Query: 2520 MPGFKAEGPEVDVNL---PKADVDISGPK--VDIEGPDVNIEGPEGKLKGPKLKMPE--M 2572 +PG K E + ++ PK + GP + GP I GP G P L P Sbjct: 151 IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGP-TGIPGPIGPPGPPGLMGPPGPP 209 Query: 2573 NIKAPKISMPDFDLHLKGPK-VKGDVDVSLPKVE----GDLKGPEVDIKGPKVDINAP-D 2626 + PK +M L+ +GPK KG+ + P + K P +D++ K D P D Sbjct: 210 GLPGPKGNM---GLNFQGPKGEKGEQGLQGPPGPPGQISEQKRP-IDVEFQKGDQGLPGD 265 Query: 2627 VGVQGPDWHLKMPKVKMPKFSMPGFKGE----GPDGDVKLPKADIDVSGPKVDIEGPDVN 2682 G GP P ++ P G KGE G G P D + P + D Sbjct: 266 RGPPGP------PGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPG 319 Query: 2683 IEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKV----KGDVDV-SLPKVEGDLK 2737 G G+ G K + + P P + + G + KG++ + LP +G+ Sbjct: 320 YPGEPGR-DGEKGQKGDTGPPGP----PGLVIPRPGTGITIGEKGNIGLPGLPGEKGERG 374 Query: 2738 GPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKADIDV 2797 P I+GP P V GP PGF GE Sbjct: 375 FP--GIQGPPGLPGPPGAAVMGPP-------------GPPGFPGE--------------- 404 Query: 2798 SGPKVDVECPDVNIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTG 2857 G K D P ++I GP G P P + P GP I ++ Sbjct: 405 RGQKGDEGPPGISIPGPPGLDGQPG---------APGLPGPP---GPAGPHIPPSDEICE 452 Query: 2858 PKVEGDLKGP-------EVDLKGPKVD--IDVPDVNVQGPDWHLKMPKMKMPKFSM--PG 2906 P G P E +KG K D + + GP +P + P S+ PG Sbjct: 453 PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG 512 Query: 2907 FKAEGPEVDVNLPKADVDVSG-------PKVDVEGPDV----NIEGPEGKLKGPKFK-MP 2954 K E + PK + G P E D+ ++G +G+L P +P Sbjct: 513 QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572 Query: 2955 EMNIKAPKIPMPDFDLHLKGPKVK-GDVDIS-------------LPKVEGDLKGPEVDIR 3000 + P P D L GPK + G + LP G + P Sbjct: 573 GL----PGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPP 628 Query: 3001 GPQVDIDVPDVGVQGPDWHLKMPKVKMPK------FSMPGFKG----EGPDVDVNLPKAD 3050 GP V + G+QG + P + PK + PG G G D DV LP Sbjct: 629 GP-----VGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDP 683 Query: 3051 --------LDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKG 3102 + G K + +P + + GP G P P P + L+G Sbjct: 684 GLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPG------RIGLEG 737 Query: 3103 PKVKGDMDVSLPKVEGDMKVPDVDIKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISMPG 3162 P P G P + GP GP +PG Sbjct: 738 PP-------GPPGFPGPKGEPGFALPGPP-----------GPP-------------GLPG 766 Query: 3163 FKGE-GPEVDVNLP-------KADLD-VSGPKVDVDVPDVNIEGPDAKLKGPKFK--MPE 3211 FKG GP+ D P + LD + GPK DV GP+ + GP +P Sbjct: 767 FKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV--------GPNGQ-PGPMGPPGLPG 817 Query: 3212 MNIKAPKISMPDLDLNLKGPKMKGEVDVSLANVEGDLKGPALDIKGPKIDVDAPDI 3267 + ++ P P + + P + G + +GD P LD+ GP + +P I Sbjct: 818 IGVQGPP-GPPGIPGPIGQPGLHG-----IPGEKGDPGPPGLDVPGPPGERGSPGI 867 Score = 47.4 bits (111), Expect = 4e-04 Identities = 168/698 (24%), Positives = 247/698 (35%), Gaps = 144/698 (20%) Query: 3500 KGDINIEGPSMNIEGPDLNVEGPEGGLKGPKFKMPDMNIKAPKISMPDIDLNLKGPKVKG 3559 KGD EGP P +++ GP G D AP + P GP + Sbjct: 408 KGD---EGP------PGISIPGPPG---------LDGQPGAPGLPGPP---GPAGPHIPP 446 Query: 3560 DVDISLPKLEGDLKGP-------EVDIKGPKVD--INAPDVDVHGPDWHLKMPKVKMPKF 3610 +I P G P E +KG K D N + GP +P + P Sbjct: 447 SDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPG 506 Query: 3611 SM--PGFKGEGPEVDVTLPKADIDISGPNVDVDVPDVNIEGPDAK----LKGPKFKMPEM 3664 S+ PG KGE + T PK I G P E D +KG K ++ Sbjct: 507 SLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSP 566 Query: 3665 NIKA----PKISMPDFDLNLKGPKMKGDVVV-----------SLPKVEGDLKGPEVDIKG 3709 P D L GPK + + LP + G++ G Sbjct: 567 GAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFG 626 Query: 3710 PKVDIDTPDIN-IEGSEGK--FKGPKFKIPEMHLKAPKISMP-----DIDLNLKG-PKVK 3760 P + I + G+ G+ GPK + + K +P D D+ L G P + Sbjct: 627 PPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP 686 Query: 3761 GDVDV-SLPKMEGDLKGPEVDIKGPKVDINAPDVD-------------VQGPDWHLKMPK 3806 G + +P +G+ P + + GP P + ++GP P Sbjct: 687 GQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG 746 Query: 3807 VK-MPKFSMPG---------FKGE-GPDVDVNLP-------KADLD-VSGPKVDIDVPDV 3847 K P F++PG FKG GP D P + LD + GPK D+ Sbjct: 747 PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV----- 801 Query: 3848 NIEGPEGKLKGPKFK--MPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMQVP 3905 GP G+ GP +P + ++ P P I + P + G +P +GD P Sbjct: 802 ---GPNGQ-PGPMGPPGLPGIGVQGPP-GPPGIPGPIGQPGLHG-----IPGEKGDPGPP 851 Query: 3906 DLDIKGPKVDINAPDVDVR----GPDWHLKMPKIKMPKISMPGFKGEGPEVDVNLPKADL 3961 LD+ GP + +P + GP +P K PG KGE + P L Sbjct: 852 GLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPG-KAGASGFPGTKGEMGMMGPPGPPGPL 910 Query: 3962 DVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDV 4021 + G VP ++G D L+G P + P + KG + Sbjct: 911 GIPGRS---GVP--GLKGDDG-LQG-----------QPGLPGPTGEKGSKG-------EP 946 Query: 4022 SLPKMEGDLKAPEVDIKGPKVDIDAPDV-DVHGPDWHLKMP-KVKMPKFS-MPGFKG-EG 4077 LP G + + KG K + P + V GP + +P P S PG G G Sbjct: 947 GLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPG 1006 Query: 4078 PEVDVNLPKADIDVSGPKVDIDTPDIDIHGPEGKLKGP 4115 P+ + LP + P + D+ GP+G ++GP Sbjct: 1007 PKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQG-VEGP 1043 Score = 47.0 bits (110), Expect = 6e-04 Identities = 129/480 (26%), Positives = 165/480 (34%), Gaps = 80/480 (16%) Query: 5242 GIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPD--VSLKGP-GVDLPSVNLSMPKVS 5298 GIPG+K E G + + LP +G+ P GP L GP G+ P P + Sbjct: 150 GIPGMKGEPGSI-IMSSLPGPKGNPGYP-----GPPGIQGLPGPTGIPGPIGPPGPPGLM 203 Query: 5299 GPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLSGVGGKMQVGGDGVK----VPGIDATT 5354 GP L GP KG++ GLN G G+ G G++ PG + Sbjct: 204 GPPGPPGLPGP--KGNM------------GLNFQGPKGEK--GEQGLQGPPGPPGQISEQ 247 Query: 5355 KLNVGAP----DVTLRG-------PSLQGDLAVSGDIKCPKVSVGAPDL----SLEASEG 5399 K + D L G P ++G G K K G P + G Sbjct: 248 KRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENG 307 Query: 5400 SIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRIS-APNVDFNLEG 5458 +P + PG D KG +G PG+ + G I+ + L G Sbjct: 308 QPGIPGLPGDPGYPGEPGRDGEKGQKGD--TGPPGPPGLVIPRPGTGITIGEKGNIGLPG 365 Query: 5459 -PKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQ 5517 P KG G G I+GP G PG V G G PG + D PG+++ P G Sbjct: 366 LPGEKGERGFPG-IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGL 424 Query: 5518 ISGPEIKG--GLKGSEVGFHGAAPDISVKGPAFNMASP--------------ESDFGINL 5561 P G G G + +I GP SP + D N Sbjct: 425 DGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNC 484 Query: 5562 KGPKIKGGADVSG--GVSAPDISLG-EGHLSVKGSGGEW--KG----PQVSSALNLDTSK 5612 G I G G G+ P SLG G KG G KG P A SK Sbjct: 485 IGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSK 544 Query: 5613 FAGG--LHFSGPKVEGGVKGGQIGLQAPGLSVSGPQGHLESGSGKVTFPKMKIPKFTFSG 5670 G L F G K + G G PGL + Q L G PK + TF G Sbjct: 545 GEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPG----PKGEPGGITFKG 600 Score = 42.4 bits (98), Expect = 0.014 Identities = 164/684 (23%), Positives = 233/684 (34%), Gaps = 149/684 (21%) Query: 291 VQGPSLESGDHGKIKFPTMKVPKFGVSTGREGQTPKAGLR-VSAPEVSVGHKG-----GK 344 +QG GD G F + TG G + GL + P S+G G G+ Sbjct: 467 LQGEQGVKGDKGDTCFNC-------IGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQ 519 Query: 345 PGLTIQAPQLEVSVPSA----NIEGLEGKLKGPQITGPSLEGDLGLKGAK-PQGHIGVDA 399 G T P+ +P A G +G+ G +T P ++GD G G+ G G+ Sbjct: 520 AGAT--GPKGLPGIPGAPGAPGFPGSKGE-PGDILTFPGMKGDKGELGSPGAPGLPGLPG 576 Query: 400 SAPQIG-GSITGPSVEV--------QAPDIDVQGPGSKLNVPKMKVPKFSVSGAKGEETG 450 + Q G + GP E + P + PG N+ M P F G GE+ Sbjct: 577 TPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGI 636 Query: 451 IDVTLPTGEVTVPGVSGD--VSLPEIATGGLEGKMKGTKVKTPEMIIQKPKISMQDVDLS 508 V G+ +PG GD ++ + GL G +D D+ Sbjct: 637 QGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGN------------------PGRDGDVG 678 Query: 509 L-GSPKLKGDIKVSAPGVQGDVKGPQVALKGSRVDIETPNLEGTLTGPRLGSPSGKTGT- 566 L G P L G + PG+ G P + I P G P + P G GT Sbjct: 679 LPGDPGLPG--QPGLPGIPGSKGEPGIP------GIGLPGPPGPKGFPGIPGPPGAPGTP 730 Query: 567 CRISMSEVDLNVAAPKVKGGVDVTLPRVEGKVKVPEV-DVRGPKVDVSAPDVEAHGPEWN 625 RI + P KG LP G +P GPK D P GP Sbjct: 731 GRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFP-----GP--- 782 Query: 626 LKMPKMKMPTFSTPGAKGEGPDVHMTLPKGDISISGPKVNVEAPDVNLEGLGGKLKGPDV 685 PG G + PKGD+ +G + P L G+G ++GP Sbjct: 783 -------------PGPPGRTGLDGLPGPKGDVGPNGQPGPMGPP--GLPGIG--VQGPP- 824 Query: 686 KLPDMSVKTPKISMPDVDLHVKGTKVKGEYDVTVPKLEGELKGPKVDIDAPDVDVHGPDW 745 P I P + P L G + G K D P +DV GP Sbjct: 825 -------GPPGIPGP----------------IGQPGLHG-IPGEKGDPGPPGLDVPGPPG 860 Query: 746 HLKMPKMKMPKFSVPGFKAE-GPEVDVNLP-----------KADVDISGPKIDVTAPDVS 793 P +PG GP LP K ++ + GP P Sbjct: 861 ERGSP-------GIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP----PGPPGP 909 Query: 794 IEEPEGKLKGPKFKMPEMNIKVPKISMPDVDLHLKG-PNVKGEYDVTMPKVESEIKVPDV 852 + P G+ P K + P + P + KG P + G P + + Sbjct: 910 LGIP-GRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNL--------L 960 Query: 853 ELKSAKMDIDVPDVE-VQGPDWHLKMP-KMKMPKFS-MPGFKA-EGPEVDVNLPKADVDI 908 K K + +P + V GP + +P P S PG GP+ + LP I Sbjct: 961 GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI 1020 Query: 909 SGPKVGVEVPDVNIEGPEGKLKGP 932 P + + D+ GP+G ++GP Sbjct: 1021 GPPGLKGTIGDMGFPGPQG-VEGP 1043 Score = 42.4 bits (98), Expect = 0.014 Identities = 276/1149 (24%), Positives = 397/1149 (34%), Gaps = 262/1149 (22%) Query: 2025 IKGPKMD--IDAPDVDVHGPDWHLKMPKMKMPKFSM--PGFKAE-------GPEVDVNLP 2073 +KG K D + + GP +P + P S+ PG K E GP+ +P Sbjct: 473 VKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIP 532 Query: 2074 KADVVVSGPKVDVEVPDV----SLEGPEGKLKGPKLK-MPEMHFKAPKISMPDVDLHLKG 2128 A P E D+ ++G +G+L P +P + + +P L G Sbjct: 533 GAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPG----LPG 588 Query: 2129 PK-------VKGDV----DVSLPKLEGDL----------TGPSVDVEVPDVELECPDAKL 2167 PK KG+ + LP L G++ GP + + V + Sbjct: 589 PKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGI 648 Query: 2168 KGPKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMDV-SVPKVEGEMKVPDVDIRGPKVD 2226 GPK + + K +P P GD+ + P + G+ +P + G K + Sbjct: 649 PGPKGDPGQTITQPGKPGLPG------NPGRDGDVGLPGDPGLPGQPGLPGIP--GSKGE 700 Query: 2227 IDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKGEGPEVDVNLPKADVDVSGPKVDVEVPDV 2286 P + + GP P + P PG G + + P GPK + P Sbjct: 701 PGIPGIGLPGPPGPKGFPGIPGP----PGAPGTPGRIGLEGPPGPPGFPGPKGE---PGF 753 Query: 2287 SLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVDVSAPK-------LEG 2339 +L GP G P FK GPK GD P L+G Sbjct: 754 ALPGPPGPPGLPGFK------------------GALGPK--GDRGFPGPPGPPGRTGLDG 793 Query: 2340 ELKGPELDV-----KGPKLDADMPEVAVEGPNGKWKTPKFKMPDMHFKAPKISMPDLDLH 2394 L GP+ DV GP +P + V+GP G P I P Sbjct: 794 -LPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGP---------------PGIPGP----- 832 Query: 2395 LKSPKAKGEVDVDVPKLEGDLKGPHVDVSGPDIDIEGPEGKLKGPKFKMPDMHFKAPNIS 2454 + P L G + G D P +D+ GP G+ P AP Sbjct: 833 -----------IGQPGLHG-IPGEKGDPGPPGLDVPGPPGERGSPGIP------GAPGPI 874 Query: 2455 MPDVDLNLKG-------PKIKGDVD-VSVPEVEGKLEVPDMNIRGPKVDVNAPDVQAPDW 2506 P L G P KG++ + P G L +P + P ++ D Sbjct: 875 GPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRS--------GVPGLKGDDG 926 Query: 2507 HLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDIEGP-DVNIEGPEGKLKGP 2565 P +PG E K + + GP GP D N+ G +G+ P Sbjct: 927 LQGQP-------GLPGPTGEKGS------KGEPGLPGP----PGPMDPNLLGSKGEKGEP 969 Query: 2566 KLKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGD--LKGPEVDIKGPKVDIN 2623 L P +S P L G D P + G L GP GPK + Sbjct: 970 GLP------GIPGVSGPKGYQGLPG-------DPGQPGLSGQPGLPGP----PGPKGNPG 1012 Query: 2624 AP-DVGVQGPDWHLKMPKVK--MPKFSMPGFKG-EGPDGDVKLP--KADIDVSGPKVDIE 2677 P G+ GP P +K + PG +G EGP G +P + G K D Sbjct: 1013 LPGQPGLIGP------PGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKG 1066 Query: 2678 GPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDV-DVSLPKVEG-- 2734 P ++ G G L GPK P + P +KG V D LP + G Sbjct: 1067 DPGISSIGLPG-LPGPK-------------GEPGLPGYPGNPGIKGSVGDPGLPGLPGTP 1112 Query: 2735 DLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKIKMPKISMPGFKGE-GPDVDVNLPKA 2793 KG P + GP + +P P + G G+ GP + P Sbjct: 1113 GAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGP-VGGGGHPGQPGPPGEKGKPGQ 1171 Query: 2794 DIDVSGPKVDVECPDVNIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDV 2853 D + GP G +G+ P F P P +S D L P I G+ Sbjct: 1172 D-GIPGP-----------AGQKGEPGQPGFGNPGPP-GLPGLSGQKGDGGL--PGIPGNP 1216 Query: 2854 DVTGPKVEGDLKG-PEVDLKGPKVDIDVPDVNVQGPDWHLKMPKMKMPKFSMPGFKA-EG 2911 + GPK E G P V +GP P ++GP + P+ + GF+ G Sbjct: 1217 GLPGPKGEPGFHGFPGV--QGPPGPPGSPGPALEGPKGN-PGPQGPPGRPGPTGFQGLPG 1273 Query: 2912 PEVDVNLPKADVDVSGPKVDVEGPDV-------NIEGPEGKLKGPKFKMPEMNIKA-PKI 2963 PE LP + + G K + P + +GP G L+G + +K P + Sbjct: 1274 PEGPPGLP-GNGGIKGEKGNPGQPGLPGLPGLKGDQGPPG-LQGNPGRPGLNGMKGDPGL 1331 Query: 2964 P-MPDFDLHLKGPKVKGDVDISLPKVEGDLKGP--EVDIRGPQ-----VDIDVPDVGVQG 3015 P +P F +KGP G + P+ E L GP + GP + D G+ G Sbjct: 1332 PGVPGFP-GMKGP--SGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPG 1388 Query: 3016 PDWHLKMPKVKMPKFSMPGFKGEGPDVDVN-LPKADLDVSGPKVDIDVPDV----NIEGP 3070 +P + P+ +PG G D N LP D G K D +P ++GP Sbjct: 1389 QPGLKGLPGPQGPQ-GLPGPTGPPGDPGRNGLPGFD-GAGGRKGDPGLPGQPGTRGLDGP 1446 Query: 3071 EGK--LKGP 3077 G L+GP Sbjct: 1447 PGPDGLQGP 1455 Score = 38.1 bits (87), Expect = 0.26 Identities = 254/1033 (24%), Positives = 358/1033 (34%), Gaps = 243/1033 (23%) Query: 2939 IEGPEGKLKGPKFKMPEMNIKAPKIPMPDFDLHLKGPKVKGDVDISLPKVEGDLKGPEVD 2998 ++GP G P K +I +P P + GP P ++G L GP Sbjct: 142 LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGP----------PGIQG-LPGP-TG 189 Query: 2999 IRGPQVDIDVPDV-GVQGPDWHLKMPKVKMP-KFSMP-GFKGE-------GPDVDVNLPK 3048 I GP P + G GP L PK M F P G KGE GP ++ K Sbjct: 190 IPGPIGPPGPPGLMGPPGPPG-LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQK 248 Query: 3049 ADLDVSGPKVDIDVPD-------VNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLK 3101 +DV K D +P I GP G G K + E + K P D Sbjct: 249 RPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQG-EPGKRGKPGKDGENG 307 Query: 3102 GPKVKGDMDVSLPKVEGDMKVPDVD-IKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISM 3160 P + G LP G P D KG K D P GP P + +P+ Sbjct: 308 QPGIPG-----LPGDPGYPGEPGRDGEKGQKGDTGPP-----GP------PGLVIPRPGT 351 Query: 3161 PGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKIS 3220 GE + ++ LP + G K + P I+GP L GP P + P Sbjct: 352 GITIGE--KGNIGLP----GLPGEKGERGFP--GIQGPPG-LPGP----PGAAVMGPP-- 396 Query: 3221 MPDLDLNLKGPKMKGEVDVSLANVEGDLKGPALDIKGPK-IDVDAPDIDIHGPDAKLKGP 3279 P GE +GD P + I GP +D + GP GP Sbjct: 397 --------GPPGFPGE-----RGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPA-GP 442 Query: 3280 KLKMPDMHVNMPKISMPEIDLNLKGSKLKGDVDVSGPKLEGDIKAPSLDIKGPEVDVSGP 3339 + P + P P KG L+G+ V G K + I GP P Sbjct: 443 HIP-PSDEICEPGPPGPPGSPGDKG--LQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLP 499 Query: 3340 KLNIEGKSKKSRFKLPKFNFSGSKVQTPEVDVKGKKPDIDITGPKVDINAPDVEVQGKVK 3399 L S F G K G+K TGPK P Sbjct: 500 GLPGPPGS---------LGFPGQK---------GEKGQAGATGPKGLPGIPGAPGAPGFP 541 Query: 3400 GSKFKMPFLSISSPKVSMPDVELNLKSPKVKGDLDIAGPNLEGDFKGPKVDIKAPEVNLN 3459 GSK + GD+ + P ++GD K ++ +P Sbjct: 542 GSKGE-------------------------PGDI-LTFPGMKGD----KGELGSP----G 567 Query: 3460 APDVD-VHGPDWNLKMPKMKMPKFSVSGL--KAE-GPDVAVDLP--KGDINIEGP-SMNI 3512 AP + + G +P + PK G+ K E GP LP G+I GP Sbjct: 568 APGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGP 627 Query: 3513 EGP--DLNVEGPEG-----GLKGPKFKMPDMNIKAP-KISMP-----DIDLNLKG-PKVK 3558 GP + ++G G G+ GPK P I P K +P D D+ L G P + Sbjct: 628 PGPVGEKGIQGVAGNPGQPGIPGPKGD-PGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP 686 Query: 3559 GDVDI-SLPKLEGDLKGPEVDIKGPKVDINAPDVD-------------VHGPDWHLKMPK 3604 G + +P +G+ P + + GP P + + GP P Sbjct: 687 GQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG 746 Query: 3605 VK-MPKFSMPG---------FKGE-GPEVDVTLP-------KADID-ISGPNVDVDVPDV 3645 K P F++PG FKG GP+ D P + +D + GP DV Sbjct: 747 PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV----- 801 Query: 3646 NIEGPDAKLKGPKFK--MPEMNIKAPKISMPDFDLNLKGPKMKGDVVVSLPKVEGDLKGP 3703 GP+ + GP +P + ++ P P + P + G +P +GD P Sbjct: 802 ---GPNGQ-PGPMGPPGLPGIGVQGPP-GPPGIPGPIGQPGLHG-----IPGEKGDPGPP 851 Query: 3704 EVDIKGPKVDIDTPDI----------NIEGSEGK-----FKGPKFKIPEMHLKAP----- 3743 +D+ GP + +P I G GK F G K ++ M P Sbjct: 852 GLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLG 911 Query: 3744 ---KISMPDI--DLNLKG-PKVKGDVDVSLPKMEGDLKGPE-------VDIKGPKVDINA 3790 + +P + D L+G P + G K E L GP + KG K + Sbjct: 912 IPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGL 971 Query: 3791 PDV-DVQGPDWHLKMP-KVKMPKFS-MPGFKG-EGPDVDVNLPKADLDVSGPKVDIDVPD 3846 P + V GP + +P P S PG G GP + LP + P + + D Sbjct: 972 PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGD 1031 Query: 3847 VNIEGPEGKLKGP 3859 + GP+G ++GP Sbjct: 1032 MGFPGPQG-VEGP 1043 Score = 37.0 bits (84), Expect = 0.58 Identities = 202/844 (23%), Positives = 288/844 (34%), Gaps = 216/844 (25%) Query: 3760 KGDVDV-SLPKMEGDLKGPEVDIKGPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFK 3818 KG++ + LP +G+ P I+GP P V GP PGF Sbjct: 358 KGNIGLPGLPGEKGERGFP--GIQGPPGLPGPPGAAVMGPP-------------GPPGFP 402 Query: 3819 GEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDI 3878 GE G K D P ++I GP G P AP + P Sbjct: 403 GE---------------RGQKGDEGPPGISIPGPPGLDGQPG---------APGLPGPP- 437 Query: 3879 DLNLKGPKVKGDMDVSLPKVEGDMQVP-------DLDIKGPKVD--INAPDVDVRGPDWH 3929 GP + ++ P G P + +KG K D N + GP Sbjct: 438 --GPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495 Query: 3930 LKMPKIKMP--KISMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGP 3987 +P + P + PG KGE K +GPK +P P A Sbjct: 496 PGLPGLPGPPGSLGFPGQKGE---------KGQAGATGPKGLPGIPGA----PGA----- 537 Query: 3988 KFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKVDIDAP 4047 P F P GD+ ++ P M+GD KG AP Sbjct: 538 ----------------PGFPGSKGEP---GDI-LTFPGMKGD--------KGELGSPGAP 569 Query: 4048 DVD-VHGPDWHLKMPKVKMPKFSMPG--FKGE-GPEVDVNLP--KADIDVSGPKVDIDTP 4101 + + G +P + PK G FKGE GP + LP +I GP P Sbjct: 570 GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGP------P 623 Query: 4102 DIDIHGPEGK--------------LKGPKFKMPDLHLKAPKISMP-----EVDLNLKG-P 4141 GP G+ + GPK + K +P + D+ L G P Sbjct: 624 GFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDP 683 Query: 4142 KMKGDVDV-SLPKVEGDLKGPEVDIKGPKVDIDVPDVD-------------VQGPDWHLK 4187 + G + +P +G+ P + + GP P + ++GP Sbjct: 684 GLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPG 743 Query: 4188 MPKVK-MPKFSMPG---------FKGE-GPDVDVNLP-------KADLD-VSGPKVDIDV 4228 P K P F++PG FKG GP D P + LD + GPK D+ Sbjct: 744 FPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV-- 801 Query: 4229 PDVNIEGPDAKLKGPKFK--MPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDL 4286 GP+ + GP +P + ++ P P + P + G +P +GD Sbjct: 802 ------GPNGQ-PGPMGPPGLPGIGVQGPP-GPPGIPGPIGQPGLHG-----IPGEKGDP 848 Query: 4287 KGPEVDIKGPKVDIDAPDV----DVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVTLPK 4342 P +D+ GP + +P + GP +P K PG KGE + P Sbjct: 849 GPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPG-KAGASGFPGTKGEMGMMGPPGPP 907 Query: 4343 ADIEISGPK-VDIDAPDVSIEGPDAKLKGP---KFKMPEMNIKAPKISMPDIDFNLKGPK 4398 + I G V D ++G L GP K E + P M D NL G K Sbjct: 908 GPLGIPGRSGVPGLKGDDGLQGQPG-LPGPTGEKGSKGEPGLPGPPGPM---DPNLLGSK 963 Query: 4399 -VKGDVDVSLPKVEGDLKGPEIDIKGPSLDIDTPDVN----IEGPEGKLKGPKFKMPEMN 4453 KG + LP + G + GP+ +G D P ++ + GP G P Sbjct: 964 GEKG--EPGLPGIPG-VSGPK-GYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGL 1019 Query: 4454 IKAPKISMPDFDLHLKGPK-VKGDVDVS----------LPKVESDLKGPEVDIEGPEGKL 4502 I P + D+ GP+ V+G S LP + D P + G G L Sbjct: 1020 IGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPG-L 1078 Query: 4503 KGPK 4506 GPK Sbjct: 1079 PGPK 1082 >gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sapiens] Length = 1685 Score = 79.3 bits (194), Expect = 1e-13 Identities = 179/638 (28%), Positives = 231/638 (36%), Gaps = 104/638 (16%) Query: 5160 KGPKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPSVGLEG 5219 KG K QA P + G+ P F S + D+ L P +KGD +G G Sbjct: 514 KGEKGQAGATGPK-GLPGIPGAPGAPGFPGSKGEPG--DI---LTFPGMKGDKGELGSPG 567 Query: 5220 PD--VDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQ--------LPSLEGDLRGP 5269 L G + P G+PG K E GG + LP L G++ Sbjct: 568 APGLPGLPGTPGQDGLP-------GLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPM 620 Query: 5270 DVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGL 5329 GP + G+ + N P + GP D G ++ +P + Sbjct: 621 GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGD---PGQTITQPGKPGLPGNPGRDGDV 677 Query: 5330 NLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGA 5389 L G G G +PGI + K G P + L GP G G I P + G Sbjct: 678 GLPGDPGLPGQPG----LPGIPGS-KGEPGIPGIGLPGPP--GPKGFPG-IPGPPGAPGT 729 Query: 5390 PD-LSLEASEGSIKLPKMK-LPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRI 5447 P + LE G P K P F + P + P G L GP D GP Sbjct: 730 PGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGL----PGFKGAL-GPKGDRGFPGP-- 782 Query: 5448 SAPNVDFNLEG-PKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMP---------GI 5497 P L+G P KG +G G+ GP GLPGIGVQG G +P GI Sbjct: 783 PGPPGRTGLDGLPGPKGDVGPNGQ-PGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGI 841 Query: 5498 KSSGCDVNLPGVNVKLPTGQISGPEIKG-----------GL--KGSEVGFHGAAPDISVK 5544 D PG++V P G+ P I G GL K GF G ++ + Sbjct: 842 PGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMM 901 Query: 5545 GPAFNMASPESDFGINLKG--PKIKGGADVSGGVSAPDISLGEGHLSVKGSGGE-----W 5597 GP P GI + P +KG + G P G KGS GE Sbjct: 902 GP----PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLP------GPTGEKGSKGEPGLPGP 951 Query: 5598 KGPQVSSALNLDTSKFAGGL----HFSGPKVEGGVKG--GQIGLQA-PGL-SVSGPQGH- 5648 GP + L K GL SGPK G+ G GQ GL PGL GP+G+ Sbjct: 952 PGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNP 1011 Query: 5649 -LESGSGKVTFPKMK--IPKFTFSGRELVGREMGVDVHFPKAEASIQAGAGDGEWEESEV 5705 L G + P +K I F G + V G P S G+ + + Sbjct: 1012 GLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPS-GVPGQPGSPGLPGQKGDKGDPGI 1070 Query: 5706 KLKKSKIKMPKFNFSKPKGKGGVTGSP-EASISGSKGD 5742 S I +P PKG+ G+ G P I GS GD Sbjct: 1071 ----SSIGLP--GLPGPKGEPGLPGYPGNPGIKGSVGD 1102 Score = 67.0 bits (162), Expect = 5e-10 Identities = 229/921 (24%), Positives = 316/921 (34%), Gaps = 191/921 (20%) Query: 4663 PGFKGE-GPDVDVNLPKAD--------IDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPE 4713 PG G G D DV LP + G K + +P + + GP GPK Sbjct: 665 PGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPP----GPK----- 715 Query: 4714 MSIKAPKISMPDIDLNLKGPKVKGDVDVTLPKVEGDLKGPEADIKGPKVDINTPDVDVHG 4773 P I P G + + P GP+ + P + G Sbjct: 716 --------GFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGE----------PGFALPG 757 Query: 4774 PDWHLKMPKVKMPKFSMPGFKGE-GPDVDVSLP-------KADID-VSGPKVDVDIPDVN 4824 P +PGFKG GP D P + +D + GPK DV Sbjct: 758 PPGPP----------GLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV------ 801 Query: 4825 IEGPDAKLKGPKFK--MPEINIKAPKISIPDVDLDLKGPKVKGDFDVSVPKVEGTLKGPE 4882 GP+ + GP +P I ++ P P + G + P + G + G + Sbjct: 802 --GPNGQ-PGPMGPPGLPGIGVQGPP----------GPPGIPGP--IGQPGLHG-IPGEK 845 Query: 4883 VDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLHLKAPKIGFSGPKLEGGEV 4942 D P LD GP + P + I P L KA GF G K GE+ Sbjct: 846 GDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG----LPGKAGASGFPGTK---GEM 898 Query: 4943 DLKGPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKFGFGAKSPKADIKSPSLDVTVPE 5002 + GP L + S ++G D + P G K P L Sbjct: 899 GMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLP----GPTGEKGSKGEPGLPGPPGP 954 Query: 5003 AELNLETPEISVGGKGKKSKFKMPKIH-MSGPKIKAKKQGFDLNVPGGEIDASLKAPDVD 5061 + NL +G KG+K + +P I +SGPK G D PG L P Sbjct: 955 MDPNL------LGSKGEKGEPGLPGIPGVSGPKGYQGLPG-DPGQPGLSGQPGLPGPPGP 1007 Query: 5062 VNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEFDIKSPKFKAEAPLP--SPKLEGELQA 5119 P + + P K G M FP + ++ P + P SP L G+ Sbjct: 1008 KG--NPGLPGQPGLIGPPGLKGTIGDMGFPGPQ-GVEGPPGPSGVPGQPGSPGLPGQKG- 1063 Query: 5120 PDLELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGDLKGPKVQANLGAPDI----NI 5175 + P I GL P + P + +P G+ P ++ ++G P + Sbjct: 1064 ---DKGDPGISSIGL------PGLPGPKGEPGLPGYPGN---PGIKGSVGDPGLPGLPGT 1111 Query: 5176 EGLDAKVKTPSF----GISAPQ-VSIPDVNVNLKG----------------PKIKGDVPS 5214 G + P F G P+ +S P N L G P KG Sbjct: 1112 PGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQ 1171 Query: 5215 VGLEGPDVDLQGPEAKIKFPKFSMP-KIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKL 5273 G+ GP G + + P F P G+PG+ + G LP + G+ P K Sbjct: 1172 DGIPGP----AGQKGEPGQPGFGNPGPPGLPGLSGQKGDGG----LPGIPGNPGLPGPKG 1223 Query: 5274 EGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLSG 5333 E PG P V GP GP+L+G P PGL G Sbjct: 1224 E--------PGFH------GFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGL--PG 1267 Query: 5334 VGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRG-PSLQGDLA---VSGDIKCPKVSVGA 5389 G + G+G GI K N G P L G P L+GD + G+ P ++ Sbjct: 1268 PEGPPGLPGNG----GIKGE-KGNPGQPG--LPGLPGLKGDQGPPGLQGNPGRPGLNGMK 1320 Query: 5390 PDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISA 5449 D L G P MK P PGS GP+ L GP L GP + Sbjct: 1321 GDPGLPGVPG---FPGMKGPS---GVPGS------AGPEGEPGLIGPPGPPGLPGPSGQS 1368 Query: 5450 PNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPG-IGVQGLEGNLQMPGIKSSGCDVNLPG 5508 + + P + G G G + GP GLPG G G G +PG +G PG Sbjct: 1369 IIIKGDAGPPGIPGQPGLKG-LPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDPG 1427 Query: 5509 VNVKLPTGQISGPEIKGGLKG 5529 + + T + GP GL+G Sbjct: 1428 LPGQPGTRGLDGPPGPDGLQG 1448 Score = 65.1 bits (157), Expect = 2e-09 Identities = 139/512 (27%), Positives = 179/512 (34%), Gaps = 110/512 (21%) Query: 5200 NVNLKG-PKIKGDVPSVGLEGPD-------VDLQGPEAKIKFPKFSMPK--IGIPGVKME 5249 N+ L G P KG+ G++GP + GP FP K G PG+ + Sbjct: 360 NIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIP 419 Query: 5250 GGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKG- 5308 G P L+G P L GP GP + PS + P GP KG Sbjct: 420 GP--------PGLDGQPGAPG--LPGPP-GPAGPHIP-PSDEICEPGPPGPPGSPGDKGL 467 Query: 5309 ---PSLKGD----------LDASVPSMKVHAPGL-------NLSGVGG-KMQVGGDGVK- 5346 +KGD S P + PGL G G K Q G G K Sbjct: 468 QGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKG 527 Query: 5347 VPGIDATTKL-----NVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDL-SLEASEGS 5400 +PGI + G P L P ++GD G++ P GAP L L + G Sbjct: 528 LPGIPGAPGAPGFPGSKGEPGDILTFPGMKGD---KGELGSP----GAPGLPGLPGTPGQ 580 Query: 5401 IKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAP---------- 5450 LP + P+ PG +GP + L G ++ GP P Sbjct: 581 DGLPGLPGPK---GEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQ 637 Query: 5451 NVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGI----------GVQGLEGNLQMPGIKSS 5500 V N P + G G G+ GLPG G GL G +PGI S Sbjct: 638 GVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGS 697 Query: 5501 GCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGIN 5560 + +PG+ + P G P I G G G I ++GP P Sbjct: 698 KGEPGIPGIGLPGPPGPKGFPGIPG-----PPGAPGTPGRIGLEGPPGPPGFP------- 745 Query: 5561 LKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFS 5620 GPK + G + G P + +G L KG G P LD GL Sbjct: 746 --GPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLD------GL--P 795 Query: 5621 GPKVEGGVKG-----GQIGLQAPGLSVSGPQG 5647 GPK + G G G GL PG+ V GP G Sbjct: 796 GPKGDVGPNGQPGPMGPPGL--PGIGVQGPPG 825 Score = 60.8 bits (146), Expect = 4e-08 Identities = 257/1045 (24%), Positives = 349/1045 (33%), Gaps = 198/1045 (18%) Query: 4664 GFKGEGPDVDVNLPKADIDVSGPKVDVDVPDVNIEGPDAKL--KGPKFKMPEMSIKAPKI 4721 G KG+ D N +SGP +P + GP L G K + + PK Sbjct: 472 GVKGDKGDTCFNC--IGTGISGPPGQPGLP--GLPGPPGSLGFPGQKGEKGQAGATGPK- 526 Query: 4722 SMPDIDLNLKGPKVKGDVDVTLPKVEGDLKGPEADI------KGPKVDINTPDVD----V 4771 +P I P G KG DI KG K ++ +P + Sbjct: 527 GLPGIPGAPGAPGFPGS------------KGEPGDILTFPGMKGDKGELGSPGAPGLPGL 574 Query: 4772 HGPDWHLKMPKVKMPKFSMPG--FKGE-GPDVDVSLPKADIDVS----------GPKVDV 4818 G +P + PK G FKGE GP + LP ++ GP + Sbjct: 575 PGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEK 634 Query: 4819 DIPDVNIEGPDAKLKGPKFKMPEINIKAPKISIP-----DVDLDLKG-PKVKGDFDVSVP 4872 I V + GPK + + K +P D D+ L G P + G +P Sbjct: 635 GIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQ--PGLP 692 Query: 4873 KVEGTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLHLKAPKIGF 4932 + G+ P + P + GP P + P P +IG Sbjct: 693 GIPGSKGEPGI----PGIGLPGPPGPKGFPGIPGPPGAPGTPG-------------RIGL 735 Query: 4933 SGPKLEGGEVDLKGPKVEAPSLDVHMDSPDINIEGPDVK--IPKFKKPKFGFGAKSPKAD 4990 GP G GPK E P + GP +P FK GA PK D Sbjct: 736 EGPP---GPPGFPGPKGE----------PGFALPGPPGPPGLPGFK------GALGPKGD 776 Query: 4991 IKSPSLDVTVPEAELN-LETPEISVGGKGKKSKFKMPKIHMSGPKIKAKKQGFDLNVPGG 5049 P L+ L P+ VG G+ P + P I + +PG Sbjct: 777 RGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGL----PGIGVQGPPGPPGIPGP 832 Query: 5050 EIDASLKAPDVDVNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEFDIKSPKFKAEAPLP 5109 L + GP +DV P ++ G P SP +A Sbjct: 833 IGQPGLHGIPGEKGDPGPPG---LDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS 889 Query: 5110 S-PKLEGEL-----QAPDLELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGDL--KG 5161 P +GE+ P L +P ++ P +K D P + G KG Sbjct: 890 GFPGTKGEMGMMGPPGPPGPLGIPG--------RSGVPGLKGDDGLQGQPGLPGPTGEKG 941 Query: 5162 PKVQANLGAP----DINIEGLDAKVKTPSF----GISAP-----------------QVSI 5196 K + L P D N+ G + P G+S P Q + Sbjct: 942 SKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGL 1001 Query: 5197 PDV-----NVNLKG-------PKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIP 5244 P N L G P +KG + +G GP ++GP P G+P Sbjct: 1002 PGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQ-GVEGPPGPSGVPG-QPGSPGLP 1059 Query: 5245 GVKMEGGGAEVHA-QLPSLEGDLRGPDVKLEGPDVSLKGPGVD--LPSVNLSMPKVSGPD 5301 G K + G + + LP L G P + + +KG D LP + + P Sbjct: 1060 GQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPG 1119 Query: 5302 LDLNLKGPSLKGDLDASVPSMKVHAPGLN--LSGVGGKMQVGGDGVK-VPGID-----AT 5353 L P G S P PG + G G Q G G K PG D A Sbjct: 1120 LPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAG 1179 Query: 5354 TKLNVGAPDVTLRGP-SLQGDLAVSGDIKCPKVSVGAPDLSLEASE-GSIKLPKMKLPQF 5411 K G P GP L G GD P + G P L E G P ++ P Sbjct: 1180 QKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIP-GNPGLPGPKGEPGFHGFPGVQGPPG 1238 Query: 5412 GISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPK-VKGSLGATGE 5470 +PG L +GP+ + +GP L GP EGP + G+ G GE Sbjct: 1239 PPGSPGPAL----EGPKGNPGPQGPPGRPGLPGP-----------EGPPGLPGNGGIKGE 1283 Query: 5471 IKGPTVGG--GLPGI----GVQGLEGNLQMPGIKSSGCDVNLPGV----NVKLPTG--QI 5518 P G GLPG+ G GL+GN PG+ D LPGV +K P+G Sbjct: 1284 KGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGS 1343 Query: 5519 SGPEIKGGLKG--SEVGFHG-AAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGG 5575 +GPE + GL G G G + I +KG A P L GP +G + G Sbjct: 1344 AGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGP--QGPQGLPGP 1401 Query: 5576 VSAPDISLGEGHLSVKGSGGEWKGP 5600 P G G+GG P Sbjct: 1402 TGPPGDPGRNGLPGFDGAGGRKGDP 1426 Score = 55.5 bits (132), Expect = 2e-06 Identities = 142/508 (27%), Positives = 191/508 (37%), Gaps = 81/508 (15%) Query: 209 PSGSGAASPTGSAVDIRAGAISASGPELQGA-GHSKLQVTMPGIKVGGSGVNVNAKGLDL 267 P G G P G I+ A + P + G G +T PG K G G N G D+ Sbjct: 622 PPGFGPPGPVGEK-GIQGVAGNPGQPGIPGPKGDPGQTITQPG-KPGLPG-NPGRDG-DV 677 Query: 268 GGRGGVQVPAVDISSSLGGRAVEVQGPSLE-SGDHGKIKFPTMKVPKFGVSTGREGQTPK 326 G G +P + G E P + G G FP + P G G + Sbjct: 678 GLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPP-----GAPGTPGR 732 Query: 327 AGLRVSAPEVSVGHKG--GKPGLTIQAPQLEVSVPSANIEGLEGKLKGPQITGPSLEGDL 384 GL P G G G+PG + P +P G +G L GP +GD Sbjct: 733 IGLE--GPPGPPGFPGPKGEPGFALPGPPGPPGLP-----GFKGAL------GP--KGDR 777 Query: 385 GLKGAK-PQGHIGVDASAPQIGGSI-----TGPSVEVQAPDIDVQGPGSKLNVPKM--KV 436 G G P G G+D P G + GP P I VQGP +P + Sbjct: 778 GFPGPPGPPGRTGLDG-LPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQP 836 Query: 437 PKFSVSGAKGEE--TGIDVTLPTGE---VTVPGVSGDVSLPEIATGGLEGK-----MKGT 486 + G KG+ G+DV P GE +PG G + P + GL GK GT Sbjct: 837 GLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPP--GSPGLPGKAGASGFPGT 894 Query: 487 KVKTPEMIIQKPKISMQDVDLSLGSPKLKGDIKVSAPGVQGD--VKGPQVALKGSRVDIE 544 K + M P + + G P LKGD G+QG + GP KGS+ + Sbjct: 895 KGEMGMMGPPGPPGPL-GIPGRSGVPGLKGD-----DGLQGQPGLPGP-TGEKGSKGEPG 947 Query: 545 TPNLEGTLTGPRLGS--PSGKTGTCRISMSEVDLNVAAPKVKGGV--DVTLPRVEGKVKV 600 P G + LGS G+ G I V+ PK G+ D P + G+ + Sbjct: 948 LPGPPGPMDPNLLGSKGEKGEPGLPGIP------GVSGPKGYQGLPGDPGQPGLSGQPGL 1001 Query: 601 PEVDVRGPKVDVSAPDVEAHGPEWNLKMPKMK--MPTFSTPGAKG-EGPDVHMTLP--KG 655 P GPK + P G + P +K + PG +G EGP +P G Sbjct: 1002 P--GPPGPKGNPGLP-----GQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPG 1054 Query: 656 DISISGPKVNVEAPDVNLEGLGGKLKGP 683 + G K + P ++ GL G L GP Sbjct: 1055 SPGLPGQKGDKGDPGISSIGLPG-LPGP 1081 Score = 54.3 bits (129), Expect = 4e-06 Identities = 224/889 (25%), Positives = 316/889 (35%), Gaps = 167/889 (18%) Query: 2489 IRGPKVDVNAPDVQAPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDI 2548 ++GP P ++ + M + PK + PG+ GP LP I GP + Sbjct: 142 LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGN-PGYP--GPPGIQGLP-GPTGIPGP-IGP 196 Query: 2549 EGPDVNIEGPEGK--LKGPKLKMPEMNIKAPKISMPDFDLHLKGP--------KVKGDVD 2598 GP + GP G L GPK M +N + PK + L +GP + K +D Sbjct: 197 PGPP-GLMGPPGPPGLPGPKGNMG-LNFQGPKGEKGEQGL--QGPPGPPGQISEQKRPID 252 Query: 2599 VSLPKVEGDLKG---------------PEVDIKGPKVDINAPDV-GVQGPDWHLKMPKVK 2642 V K + L G P KG K + P G G D P + Sbjct: 253 VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312 Query: 2643 -MPKFSMPGFKGE-GPDGDVKLPKADIDVSGPK-VDIEGPDVNIE-GPEGKLKGPKFKMP 2698 +P PG+ GE G DG+ K K D GP + I P I G +G + P Sbjct: 313 GLP--GDPGYPGEPGRDGE-KGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE 369 Query: 2699 EMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPK-------VEGDLKGPEVDIKGPK-VDI 2750 + P I P L GP + P +GD P + I GP +D Sbjct: 370 KGERGFPGIQGPP---GLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG 426 Query: 2751 DAPDVDVHGPDWHLKMPKIKMPKISMPGFKGE-GPDVDVNLPKADIDVSGPKVDV--ECP 2807 + GP +I PG G G D L + + V G K D C Sbjct: 427 QPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGL-QGEQGVKGDKGDTCFNCI 485 Query: 2808 DVNIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPK-IKGDVDVTGPKVEGDLKG 2866 I GP G+ P P P TGPK + G G KG Sbjct: 486 GTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKG 545 Query: 2867 PEVDL------KGPKVDIDVPDV----NVQGPDWHLKMPKMKMPKFSMPG--FKAE-GPE 2913 D+ KG K ++ P + G +P + PK G FK E GP Sbjct: 546 EPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPP 605 Query: 2914 VDVNLPKADVDVSG---PKVDVEGP--DVNIEGPEGK-----LKGPKFKMPEMNIKAPKI 2963 + LP ++ P GP + I+G G + GPK P I P Sbjct: 606 GNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGD-PGQTITQPGK 664 Query: 2964 P-MP-----DFDLHLKG-PKVKGDVDI-SLPKVEGDLKGPEVDIRGPQVDIDVPDV---- 3011 P +P D D+ L G P + G + +P +G+ P + + GP P + Sbjct: 665 PGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPP 724 Query: 3012 ---------GVQGPDWHLKMPKVK-MPKFSMPG---------FKGE-GPDVDVNLP---- 3047 G++GP P K P F++PG FKG GP D P Sbjct: 725 GAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPG 784 Query: 3048 ---KADLD-VSGPKVDIDVPDVNIEGPEGKLKGPKFK--MPEMNIKAPKISMPDIDLNLK 3101 + LD + GPK D+ GP G+ GP +P + ++ P P I + Sbjct: 785 PPGRTGLDGLPGPKGDV--------GPNGQ-PGPMGPPGLPGIGVQGPP-GPPGIPGPIG 834 Query: 3102 GPKVKGDMDVSLPKVEGDMKVPDVDIKGPKVDINAPDV-DVQGPDWHLKMPKI--KMPKI 3158 P + G +P +GD P +D+ GP + +P + GP P + K Sbjct: 835 QPGLHG-----IPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS 889 Query: 3159 SMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPK 3218 PG KGE + P L + G VP ++G D L+G P Sbjct: 890 GFPGTKGEMGMMGPPGPPGPLGIPGRS---GVP--GLKGDDG-LQG-----------QPG 932 Query: 3219 ISMPDLDLNLKG----PKMKGEVDVSLANVEGDLKGPAL----DIKGPK 3259 + P + KG P G +D +L +G+ P L + GPK Sbjct: 933 LPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPK 981 Score = 51.2 bits (121), Expect = 3e-05 Identities = 199/836 (23%), Positives = 285/836 (34%), Gaps = 207/836 (24%) Query: 2520 MPGFKAEGPEVDVNL---PKADVDISGPK--VDIEGPDVNIEGPEGKLKGPKLKMPE--M 2572 +PG K E + ++ PK + GP + GP I GP G P L P Sbjct: 151 IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGP-TGIPGPIGPPGPPGLMGPPGPP 209 Query: 2573 NIKAPKISMPDFDLHLKGPK-VKGDVDVSLPKVE----GDLKGPEVDIKGPKVDINAP-D 2626 + PK +M L+ +GPK KG+ + P + K P +D++ K D P D Sbjct: 210 GLPGPKGNM---GLNFQGPKGEKGEQGLQGPPGPPGQISEQKRP-IDVEFQKGDQGLPGD 265 Query: 2627 VGVQGPDWHLKMPKVKMPKFSMPGFKGE----GPDGDVKLPKADIDVSGPKVDIEGPDVN 2682 G GP P ++ P G KGE G G P D + P + D Sbjct: 266 RGPPGP------PGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPG 319 Query: 2683 IEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKV----KGDVDV-SLPKVEGDLK 2737 G G+ G K + + P P + + G + KG++ + LP +G+ Sbjct: 320 YPGEPGR-DGEKGQKGDTGPPGP----PGLVIPRPGTGITIGEKGNIGLPGLPGEKGERG 374 Query: 2738 GPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKADIDV 2797 P I+GP P V GP PGF GE Sbjct: 375 FP--GIQGPPGLPGPPGAAVMGPP-------------GPPGFPGE--------------- 404 Query: 2798 SGPKVDVECPDVNIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTG 2857 G K D P ++I GP G P P + P GP I ++ Sbjct: 405 RGQKGDEGPPGISIPGPPGLDGQPG---------APGLPGPP---GPAGPHIPPSDEICE 452 Query: 2858 PKVEGDLKGP-------EVDLKGPKVD--IDVPDVNVQGPDWHLKMPKMKMPKFSM--PG 2906 P G P E +KG K D + + GP +P + P S+ PG Sbjct: 453 PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG 512 Query: 2907 FKAEGPEVDVNLPKADVDVSG-------PKVDVEGPDV----NIEGPEGKLKGPKFK-MP 2954 K E + PK + G P E D+ ++G +G+L P +P Sbjct: 513 QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572 Query: 2955 EMNIKAPKIPMPDFDLHLKGPKVK-GDVDIS-------------LPKVEGDLKGPEVDIR 3000 + P P D L GPK + G + LP G + P Sbjct: 573 GL----PGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPP 628 Query: 3001 GPQVDIDVPDVGVQGPDWHLKMPKVKMPK------FSMPGFKG----EGPDVDVNLPKAD 3050 GP V + G+QG + P + PK + PG G G D DV LP Sbjct: 629 GP-----VGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDP 683 Query: 3051 --------LDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKG 3102 + G K + +P + + GP G P P P + L+G Sbjct: 684 GLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPG------RIGLEG 737 Query: 3103 PKVKGDMDVSLPKVEGDMKVPDVDIKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISMPG 3162 P P G P + GP GP +PG Sbjct: 738 PP-------GPPGFPGPKGEPGFALPGPP-----------GPP-------------GLPG 766 Query: 3163 FKGE-GPEVDVNLP-------KADLD-VSGPKVDVDVPDVNIEGPDAKLKGPKFK--MPE 3211 FKG GP+ D P + LD + GPK DV GP+ + GP +P Sbjct: 767 FKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV--------GPNGQ-PGPMGPPGLPG 817 Query: 3212 MNIKAPKISMPDLDLNLKGPKMKGEVDVSLANVEGDLKGPALDIKGPKIDVDAPDI 3267 + ++ P P + + P + G + +GD P LD+ GP + +P I Sbjct: 818 IGVQGPP-GPPGIPGPIGQPGLHG-----IPGEKGDPGPPGLDVPGPPGERGSPGI 867 Score = 47.4 bits (111), Expect = 4e-04 Identities = 168/698 (24%), Positives = 247/698 (35%), Gaps = 144/698 (20%) Query: 3500 KGDINIEGPSMNIEGPDLNVEGPEGGLKGPKFKMPDMNIKAPKISMPDIDLNLKGPKVKG 3559 KGD EGP P +++ GP G D AP + P GP + Sbjct: 408 KGD---EGP------PGISIPGPPG---------LDGQPGAPGLPGPP---GPAGPHIPP 446 Query: 3560 DVDISLPKLEGDLKGP-------EVDIKGPKVD--INAPDVDVHGPDWHLKMPKVKMPKF 3610 +I P G P E +KG K D N + GP +P + P Sbjct: 447 SDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPG 506 Query: 3611 SM--PGFKGEGPEVDVTLPKADIDISGPNVDVDVPDVNIEGPDAK----LKGPKFKMPEM 3664 S+ PG KGE + T PK I G P E D +KG K ++ Sbjct: 507 SLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSP 566 Query: 3665 NIKA----PKISMPDFDLNLKGPKMKGDVVV-----------SLPKVEGDLKGPEVDIKG 3709 P D L GPK + + LP + G++ G Sbjct: 567 GAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFG 626 Query: 3710 PKVDIDTPDIN-IEGSEGK--FKGPKFKIPEMHLKAPKISMP-----DIDLNLKG-PKVK 3760 P + I + G+ G+ GPK + + K +P D D+ L G P + Sbjct: 627 PPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP 686 Query: 3761 GDVDV-SLPKMEGDLKGPEVDIKGPKVDINAPDVD-------------VQGPDWHLKMPK 3806 G + +P +G+ P + + GP P + ++GP P Sbjct: 687 GQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG 746 Query: 3807 VK-MPKFSMPG---------FKGE-GPDVDVNLP-------KADLD-VSGPKVDIDVPDV 3847 K P F++PG FKG GP D P + LD + GPK D+ Sbjct: 747 PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV----- 801 Query: 3848 NIEGPEGKLKGPKFK--MPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMQVP 3905 GP G+ GP +P + ++ P P I + P + G +P +GD P Sbjct: 802 ---GPNGQ-PGPMGPPGLPGIGVQGPP-GPPGIPGPIGQPGLHG-----IPGEKGDPGPP 851 Query: 3906 DLDIKGPKVDINAPDVDVR----GPDWHLKMPKIKMPKISMPGFKGEGPEVDVNLPKADL 3961 LD+ GP + +P + GP +P K PG KGE + P L Sbjct: 852 GLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPG-KAGASGFPGTKGEMGMMGPPGPPGPL 910 Query: 3962 DVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDV 4021 + G VP ++G D L+G P + P + KG + Sbjct: 911 GIPGRS---GVP--GLKGDDG-LQG-----------QPGLPGPTGEKGSKG-------EP 946 Query: 4022 SLPKMEGDLKAPEVDIKGPKVDIDAPDV-DVHGPDWHLKMP-KVKMPKFS-MPGFKG-EG 4077 LP G + + KG K + P + V GP + +P P S PG G G Sbjct: 947 GLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPG 1006 Query: 4078 PEVDVNLPKADIDVSGPKVDIDTPDIDIHGPEGKLKGP 4115 P+ + LP + P + D+ GP+G ++GP Sbjct: 1007 PKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQG-VEGP 1043 Score = 47.0 bits (110), Expect = 6e-04 Identities = 129/480 (26%), Positives = 165/480 (34%), Gaps = 80/480 (16%) Query: 5242 GIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPD--VSLKGP-GVDLPSVNLSMPKVS 5298 GIPG+K E G + + LP +G+ P GP L GP G+ P P + Sbjct: 150 GIPGMKGEPGSI-IMSSLPGPKGNPGYP-----GPPGIQGLPGPTGIPGPIGPPGPPGLM 203 Query: 5299 GPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLSGVGGKMQVGGDGVK----VPGIDATT 5354 GP L GP KG++ GLN G G+ G G++ PG + Sbjct: 204 GPPGPPGLPGP--KGNM------------GLNFQGPKGEK--GEQGLQGPPGPPGQISEQ 247 Query: 5355 KLNVGAP----DVTLRG-------PSLQGDLAVSGDIKCPKVSVGAPDL----SLEASEG 5399 K + D L G P ++G G K K G P + G Sbjct: 248 KRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENG 307 Query: 5400 SIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRIS-APNVDFNLEG 5458 +P + PG D KG +G PG+ + G I+ + L G Sbjct: 308 QPGIPGLPGDPGYPGEPGRDGEKGQKGD--TGPPGPPGLVIPRPGTGITIGEKGNIGLPG 365 Query: 5459 -PKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQ 5517 P KG G G I+GP G PG V G G PG + D PG+++ P G Sbjct: 366 LPGEKGERGFPG-IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGL 424 Query: 5518 ISGPEIKG--GLKGSEVGFHGAAPDISVKGPAFNMASP--------------ESDFGINL 5561 P G G G + +I GP SP + D N Sbjct: 425 DGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNC 484 Query: 5562 KGPKIKGGADVSG--GVSAPDISLG-EGHLSVKGSGGEW--KG----PQVSSALNLDTSK 5612 G I G G G+ P SLG G KG G KG P A SK Sbjct: 485 IGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSK 544 Query: 5613 FAGG--LHFSGPKVEGGVKGGQIGLQAPGLSVSGPQGHLESGSGKVTFPKMKIPKFTFSG 5670 G L F G K + G G PGL + Q L G PK + TF G Sbjct: 545 GEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPG----PKGEPGGITFKG 600 Score = 42.4 bits (98), Expect = 0.014 Identities = 164/684 (23%), Positives = 233/684 (34%), Gaps = 149/684 (21%) Query: 291 VQGPSLESGDHGKIKFPTMKVPKFGVSTGREGQTPKAGLR-VSAPEVSVGHKG-----GK 344 +QG GD G F + TG G + GL + P S+G G G+ Sbjct: 467 LQGEQGVKGDKGDTCFNC-------IGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQ 519 Query: 345 PGLTIQAPQLEVSVPSA----NIEGLEGKLKGPQITGPSLEGDLGLKGAK-PQGHIGVDA 399 G T P+ +P A G +G+ G +T P ++GD G G+ G G+ Sbjct: 520 AGAT--GPKGLPGIPGAPGAPGFPGSKGE-PGDILTFPGMKGDKGELGSPGAPGLPGLPG 576 Query: 400 SAPQIG-GSITGPSVEV--------QAPDIDVQGPGSKLNVPKMKVPKFSVSGAKGEETG 450 + Q G + GP E + P + PG N+ M P F G GE+ Sbjct: 577 TPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGI 636 Query: 451 IDVTLPTGEVTVPGVSGD--VSLPEIATGGLEGKMKGTKVKTPEMIIQKPKISMQDVDLS 508 V G+ +PG GD ++ + GL G +D D+ Sbjct: 637 QGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGN------------------PGRDGDVG 678 Query: 509 L-GSPKLKGDIKVSAPGVQGDVKGPQVALKGSRVDIETPNLEGTLTGPRLGSPSGKTGT- 566 L G P L G + PG+ G P + I P G P + P G GT Sbjct: 679 LPGDPGLPG--QPGLPGIPGSKGEPGIP------GIGLPGPPGPKGFPGIPGPPGAPGTP 730 Query: 567 CRISMSEVDLNVAAPKVKGGVDVTLPRVEGKVKVPEV-DVRGPKVDVSAPDVEAHGPEWN 625 RI + P KG LP G +P GPK D P GP Sbjct: 731 GRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFP-----GP--- 782 Query: 626 LKMPKMKMPTFSTPGAKGEGPDVHMTLPKGDISISGPKVNVEAPDVNLEGLGGKLKGPDV 685 PG G + PKGD+ +G + P L G+G ++GP Sbjct: 783 -------------PGPPGRTGLDGLPGPKGDVGPNGQPGPMGPP--GLPGIG--VQGPP- 824 Query: 686 KLPDMSVKTPKISMPDVDLHVKGTKVKGEYDVTVPKLEGELKGPKVDIDAPDVDVHGPDW 745 P I P + P L G + G K D P +DV GP Sbjct: 825 -------GPPGIPGP----------------IGQPGLHG-IPGEKGDPGPPGLDVPGPPG 860 Query: 746 HLKMPKMKMPKFSVPGFKAE-GPEVDVNLP-----------KADVDISGPKIDVTAPDVS 793 P +PG GP LP K ++ + GP P Sbjct: 861 ERGSP-------GIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP----PGPPGP 909 Query: 794 IEEPEGKLKGPKFKMPEMNIKVPKISMPDVDLHLKG-PNVKGEYDVTMPKVESEIKVPDV 852 + P G+ P K + P + P + KG P + G P + + Sbjct: 910 LGIP-GRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNL--------L 960 Query: 853 ELKSAKMDIDVPDVE-VQGPDWHLKMP-KMKMPKFS-MPGFKA-EGPEVDVNLPKADVDI 908 K K + +P + V GP + +P P S PG GP+ + LP I Sbjct: 961 GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI 1020 Query: 909 SGPKVGVEVPDVNIEGPEGKLKGP 932 P + + D+ GP+G ++GP Sbjct: 1021 GPPGLKGTIGDMGFPGPQG-VEGP 1043 Score = 42.4 bits (98), Expect = 0.014 Identities = 277/1148 (24%), Positives = 396/1148 (34%), Gaps = 266/1148 (23%) Query: 2025 IKGPKMD--IDAPDVDVHGPDWHLKMPKMKMPKFSM--PGFKAE-------GPEVDVNLP 2073 +KG K D + + GP +P + P S+ PG K E GP+ +P Sbjct: 473 VKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIP 532 Query: 2074 KADVVVSGPKVDVEVPDV----SLEGPEGKLKGPKLK-MPEMHFKAPKISMPDVDLHLKG 2128 A P E D+ ++G +G+L P +P + + +P L G Sbjct: 533 GAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPG----LPG 588 Query: 2129 PK-------VKGDV----DVSLPKLEGDL----------TGPSVDVEVPDVELECPDAKL 2167 PK KG+ + LP L G++ GP + + V + Sbjct: 589 PKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGI 648 Query: 2168 KGPKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMDV-SVPKVEGEMKVPDVDIRGPKVD 2226 GPK + + K +P P GD+ + P + G+ +P + G K + Sbjct: 649 PGPKGDPGQTITQPGKPGLPG------NPGRDGDVGLPGDPGLPGQPGLPGIP--GSKGE 700 Query: 2227 IDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKGEGPEVDVNLPKADVDVSGPKVDVEVPDV 2286 P + + GP P + P PG G + + P GPK + P Sbjct: 701 PGIPGIGLPGPPGPKGFPGIPGP----PGAPGTPGRIGLEGPPGPPGFPGPKGE---PGF 753 Query: 2287 SLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVDVSAPK-------LEG 2339 +L GP G P FK GPK GD P L+G Sbjct: 754 ALPGPPGPPGLPGFK------------------GALGPK--GDRGFPGPPGPPGRTGLDG 793 Query: 2340 ELKGPELDV-----KGPKLDADMPEVAVEGPNGKWKTPKFKMPDMHFKAPKISMPDLDLH 2394 L GP+ DV GP +P + V+GP G P I P Sbjct: 794 -LPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGP---------------PGIPGP----- 832 Query: 2395 LKSPKAKGEVDVDVPKLEGDLKGPHVDVSGPDIDIEGPEGKLKGPKFKMPDMHFKAPNIS 2454 + P L G + G D P +D+ GP G+ P AP Sbjct: 833 -----------IGQPGLHG-IPGEKGDPGPPGLDVPGPPGERGSPGIP------GAPGPI 874 Query: 2455 MPDVDLNLKG-------PKIKGDVD-VSVPEVEGKLEVPDMNIRGPKVDVNAPDVQAPDW 2506 P L G P KG++ + P G L +P + P ++ D Sbjct: 875 GPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRS--------GVPGLKGDDG 926 Query: 2507 HLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDIEGP-DVNIEGPEGKLKGP 2565 P +PG E K + + GP GP D N+ G +G+ P Sbjct: 927 LQGQP-------GLPGPTGEKGS------KGEPGLPGP----PGPMDPNLLGSKGEKGEP 969 Query: 2566 KLKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGD--LKGPEVDIKGPKVDIN 2623 L P +S P L G D P + G L GP GPK + Sbjct: 970 GLP------GIPGVSGPKGYQGLPG-------DPGQPGLSGQPGLPGP----PGPKGNPG 1012 Query: 2624 AP-DVGVQGPDWHLKMPKVK--MPKFSMPGFKG-EGPDGDVKLP--KADIDVSGPKVDIE 2677 P G+ GP P +K + PG +G EGP G +P + G K D Sbjct: 1013 LPGQPGLIGP------PGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKG 1066 Query: 2678 GPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDV-DVSLPKVEG-- 2734 P ++ G G L GPK P + P +KG V D LP + G Sbjct: 1067 DPGISSIGLPG-LPGPK-------------GEPGLPGYPGNPGIKGSVGDPGLPGLPGTP 1112 Query: 2735 DLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKIKMPKISMPGFKGE-GPDVDVNLPKA 2793 KG P + GP + +P P + G G+ GP + P Sbjct: 1113 GAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGP-VGGGGHPGQPGPPGEKGKPGQ 1171 Query: 2794 DIDVSGPKVDVECPDVNIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDV 2853 D + GP G +G+ P F P P +S D L P I G+ Sbjct: 1172 D-GIPGP-----------AGQKGEPGQPGFGNPGPP-GLPGLSGQKGDGGL--PGIPGNP 1216 Query: 2854 DVTGPKVEGDLKG-PEVDLKGPKVDIDVPDVNVQGPDWHLKMPKMKMPKFSMPGFKAEGP 2912 + GPK E G P V +GP P ++GP + P + P PG GP Sbjct: 1217 GLPGPKGEPGFHGFPGV--QGPPGPPGSPGPALEGPKGN---PGPQGPP-GRPGL--PGP 1268 Query: 2913 EVDVNLPKADVDVSGPKVDVEGPDV-------NIEGPEGKLKGPKFKMPEMNIKA-PKIP 2964 E LP + + G K + P + +GP G L+G + +K P +P Sbjct: 1269 EGPPGLP-GNGGIKGEKGNPGQPGLPGLPGLKGDQGPPG-LQGNPGRPGLNGMKGDPGLP 1326 Query: 2965 -MPDFDLHLKGPKVKGDVDISLPKVEGDLKGP--EVDIRGPQ-----VDIDVPDVGVQGP 3016 +P F +KGP G + P+ E L GP + GP + D G+ G Sbjct: 1327 GVPGFP-GMKGP--SGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQ 1383 Query: 3017 DWHLKMPKVKMPKFSMPGFKGEGPDVDVN-LPKADLDVSGPKVDIDVPDV----NIEGPE 3071 +P + P+ +PG G D N LP D G K D +P ++GP Sbjct: 1384 PGLKGLPGPQGPQ-GLPGPTGPPGDPGRNGLPGFD-GAGGRKGDPGLPGQPGTRGLDGPP 1441 Query: 3072 GK--LKGP 3077 G L+GP Sbjct: 1442 GPDGLQGP 1449 Score = 38.1 bits (87), Expect = 0.26 Identities = 254/1033 (24%), Positives = 358/1033 (34%), Gaps = 243/1033 (23%) Query: 2939 IEGPEGKLKGPKFKMPEMNIKAPKIPMPDFDLHLKGPKVKGDVDISLPKVEGDLKGPEVD 2998 ++GP G P K +I +P P + GP P ++G L GP Sbjct: 142 LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGP----------PGIQG-LPGP-TG 189 Query: 2999 IRGPQVDIDVPDV-GVQGPDWHLKMPKVKMP-KFSMP-GFKGE-------GPDVDVNLPK 3048 I GP P + G GP L PK M F P G KGE GP ++ K Sbjct: 190 IPGPIGPPGPPGLMGPPGPPG-LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQK 248 Query: 3049 ADLDVSGPKVDIDVPD-------VNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLK 3101 +DV K D +P I GP G G K + E + K P D Sbjct: 249 RPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQG-EPGKRGKPGKDGENG 307 Query: 3102 GPKVKGDMDVSLPKVEGDMKVPDVD-IKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISM 3160 P + G LP G P D KG K D P GP P + +P+ Sbjct: 308 QPGIPG-----LPGDPGYPGEPGRDGEKGQKGDTGPP-----GP------PGLVIPRPGT 351 Query: 3161 PGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKIS 3220 GE + ++ LP + G K + P I+GP L GP P + P Sbjct: 352 GITIGE--KGNIGLP----GLPGEKGERGFP--GIQGPPG-LPGP----PGAAVMGPP-- 396 Query: 3221 MPDLDLNLKGPKMKGEVDVSLANVEGDLKGPALDIKGPK-IDVDAPDIDIHGPDAKLKGP 3279 P GE +GD P + I GP +D + GP GP Sbjct: 397 --------GPPGFPGE-----RGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPA-GP 442 Query: 3280 KLKMPDMHVNMPKISMPEIDLNLKGSKLKGDVDVSGPKLEGDIKAPSLDIKGPEVDVSGP 3339 + P + P P KG L+G+ V G K + I GP P Sbjct: 443 HIP-PSDEICEPGPPGPPGSPGDKG--LQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLP 499 Query: 3340 KLNIEGKSKKSRFKLPKFNFSGSKVQTPEVDVKGKKPDIDITGPKVDINAPDVEVQGKVK 3399 L S F G K G+K TGPK P Sbjct: 500 GLPGPPGS---------LGFPGQK---------GEKGQAGATGPKGLPGIPGAPGAPGFP 541 Query: 3400 GSKFKMPFLSISSPKVSMPDVELNLKSPKVKGDLDIAGPNLEGDFKGPKVDIKAPEVNLN 3459 GSK + GD+ + P ++GD K ++ +P Sbjct: 542 GSKGE-------------------------PGDI-LTFPGMKGD----KGELGSP----G 567 Query: 3460 APDVD-VHGPDWNLKMPKMKMPKFSVSGL--KAE-GPDVAVDLP--KGDINIEGP-SMNI 3512 AP + + G +P + PK G+ K E GP LP G+I GP Sbjct: 568 APGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGP 627 Query: 3513 EGP--DLNVEGPEG-----GLKGPKFKMPDMNIKAP-KISMP-----DIDLNLKG-PKVK 3558 GP + ++G G G+ GPK P I P K +P D D+ L G P + Sbjct: 628 PGPVGEKGIQGVAGNPGQPGIPGPKGD-PGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP 686 Query: 3559 GDVDI-SLPKLEGDLKGPEVDIKGPKVDINAPDVD-------------VHGPDWHLKMPK 3604 G + +P +G+ P + + GP P + + GP P Sbjct: 687 GQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG 746 Query: 3605 VK-MPKFSMPG---------FKGE-GPEVDVTLP-------KADID-ISGPNVDVDVPDV 3645 K P F++PG FKG GP+ D P + +D + GP DV Sbjct: 747 PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV----- 801 Query: 3646 NIEGPDAKLKGPKFK--MPEMNIKAPKISMPDFDLNLKGPKMKGDVVVSLPKVEGDLKGP 3703 GP+ + GP +P + ++ P P + P + G +P +GD P Sbjct: 802 ---GPNGQ-PGPMGPPGLPGIGVQGPP-GPPGIPGPIGQPGLHG-----IPGEKGDPGPP 851 Query: 3704 EVDIKGPKVDIDTPDI----------NIEGSEGK-----FKGPKFKIPEMHLKAP----- 3743 +D+ GP + +P I G GK F G K ++ M P Sbjct: 852 GLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLG 911 Query: 3744 ---KISMPDI--DLNLKG-PKVKGDVDVSLPKMEGDLKGPE-------VDIKGPKVDINA 3790 + +P + D L+G P + G K E L GP + KG K + Sbjct: 912 IPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGL 971 Query: 3791 PDV-DVQGPDWHLKMP-KVKMPKFS-MPGFKG-EGPDVDVNLPKADLDVSGPKVDIDVPD 3846 P + V GP + +P P S PG G GP + LP + P + + D Sbjct: 972 PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGD 1031 Query: 3847 VNIEGPEGKLKGP 3859 + GP+G ++GP Sbjct: 1032 MGFPGPQG-VEGP 1043 Score = 37.0 bits (84), Expect = 0.58 Identities = 202/844 (23%), Positives = 288/844 (34%), Gaps = 216/844 (25%) Query: 3760 KGDVDV-SLPKMEGDLKGPEVDIKGPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFK 3818 KG++ + LP +G+ P I+GP P V GP PGF Sbjct: 358 KGNIGLPGLPGEKGERGFP--GIQGPPGLPGPPGAAVMGPP-------------GPPGFP 402 Query: 3819 GEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDI 3878 GE G K D P ++I GP G P AP + P Sbjct: 403 GE---------------RGQKGDEGPPGISIPGPPGLDGQPG---------APGLPGPP- 437 Query: 3879 DLNLKGPKVKGDMDVSLPKVEGDMQVP-------DLDIKGPKVD--INAPDVDVRGPDWH 3929 GP + ++ P G P + +KG K D N + GP Sbjct: 438 --GPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495 Query: 3930 LKMPKIKMP--KISMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGP 3987 +P + P + PG KGE K +GPK +P P A Sbjct: 496 PGLPGLPGPPGSLGFPGQKGE---------KGQAGATGPKGLPGIPGA----PGA----- 537 Query: 3988 KFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKVDIDAP 4047 P F P GD+ ++ P M+GD KG AP Sbjct: 538 ----------------PGFPGSKGEP---GDI-LTFPGMKGD--------KGELGSPGAP 569 Query: 4048 DVD-VHGPDWHLKMPKVKMPKFSMPG--FKGE-GPEVDVNLP--KADIDVSGPKVDIDTP 4101 + + G +P + PK G FKGE GP + LP +I GP P Sbjct: 570 GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGP------P 623 Query: 4102 DIDIHGPEGK--------------LKGPKFKMPDLHLKAPKISMP-----EVDLNLKG-P 4141 GP G+ + GPK + K +P + D+ L G P Sbjct: 624 GFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDP 683 Query: 4142 KMKGDVDV-SLPKVEGDLKGPEVDIKGPKVDIDVPDVD-------------VQGPDWHLK 4187 + G + +P +G+ P + + GP P + ++GP Sbjct: 684 GLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPG 743 Query: 4188 MPKVK-MPKFSMPG---------FKGE-GPDVDVNLP-------KADLD-VSGPKVDIDV 4228 P K P F++PG FKG GP D P + LD + GPK D+ Sbjct: 744 FPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV-- 801 Query: 4229 PDVNIEGPDAKLKGPKFK--MPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDL 4286 GP+ + GP +P + ++ P P + P + G +P +GD Sbjct: 802 ------GPNGQ-PGPMGPPGLPGIGVQGPP-GPPGIPGPIGQPGLHG-----IPGEKGDP 848 Query: 4287 KGPEVDIKGPKVDIDAPDV----DVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVTLPK 4342 P +D+ GP + +P + GP +P K PG KGE + P Sbjct: 849 GPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPG-KAGASGFPGTKGEMGMMGPPGPP 907 Query: 4343 ADIEISGPK-VDIDAPDVSIEGPDAKLKGP---KFKMPEMNIKAPKISMPDIDFNLKGPK 4398 + I G V D ++G L GP K E + P M D NL G K Sbjct: 908 GPLGIPGRSGVPGLKGDDGLQGQPG-LPGPTGEKGSKGEPGLPGPPGPM---DPNLLGSK 963 Query: 4399 -VKGDVDVSLPKVEGDLKGPEIDIKGPSLDIDTPDVN----IEGPEGKLKGPKFKMPEMN 4453 KG + LP + G + GP+ +G D P ++ + GP G P Sbjct: 964 GEKG--EPGLPGIPG-VSGPK-GYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGL 1019 Query: 4454 IKAPKISMPDFDLHLKGPK-VKGDVDVS----------LPKVESDLKGPEVDIEGPEGKL 4502 I P + D+ GP+ V+G S LP + D P + G G L Sbjct: 1020 IGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPG-L 1078 Query: 4503 KGPK 4506 GPK Sbjct: 1079 PGPK 1082 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 79.3 bits (194), Expect = 1e-13 Identities = 179/638 (28%), Positives = 231/638 (36%), Gaps = 104/638 (16%) Query: 5160 KGPKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPSVGLEG 5219 KG K QA P + G+ P F S + D+ L P +KGD +G G Sbjct: 514 KGEKGQAGATGPK-GLPGIPGAPGAPGFPGSKGEPG--DI---LTFPGMKGDKGELGSPG 567 Query: 5220 PD--VDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQ--------LPSLEGDLRGP 5269 L G + P G+PG K E GG + LP L G++ Sbjct: 568 APGLPGLPGTPGQDGLP-------GLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPM 620 Query: 5270 DVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGL 5329 GP + G+ + N P + GP D G ++ +P + Sbjct: 621 GPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGD---PGQTITQPGKPGLPGNPGRDGDV 677 Query: 5330 NLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGA 5389 L G G G +PGI + K G P + L GP G G I P + G Sbjct: 678 GLPGDPGLPGQPG----LPGIPGS-KGEPGIPGIGLPGPP--GPKGFPG-IPGPPGAPGT 729 Query: 5390 PD-LSLEASEGSIKLPKMK-LPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRI 5447 P + LE G P K P F + P + P G L GP D GP Sbjct: 730 PGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGL----PGFKGAL-GPKGDRGFPGP-- 782 Query: 5448 SAPNVDFNLEG-PKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMP---------GI 5497 P L+G P KG +G G+ GP GLPGIGVQG G +P GI Sbjct: 783 PGPPGRTGLDGLPGPKGDVGPNGQ-PGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGI 841 Query: 5498 KSSGCDVNLPGVNVKLPTGQISGPEIKG-----------GL--KGSEVGFHGAAPDISVK 5544 D PG++V P G+ P I G GL K GF G ++ + Sbjct: 842 PGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMM 901 Query: 5545 GPAFNMASPESDFGINLKG--PKIKGGADVSGGVSAPDISLGEGHLSVKGSGGE-----W 5597 GP P GI + P +KG + G P G KGS GE Sbjct: 902 GP----PGPPGPLGIPGRSGVPGLKGDDGLQGQPGLP------GPTGEKGSKGEPGLPGP 951 Query: 5598 KGPQVSSALNLDTSKFAGGL----HFSGPKVEGGVKG--GQIGLQA-PGL-SVSGPQGH- 5648 GP + L K GL SGPK G+ G GQ GL PGL GP+G+ Sbjct: 952 PGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNP 1011 Query: 5649 -LESGSGKVTFPKMK--IPKFTFSGRELVGREMGVDVHFPKAEASIQAGAGDGEWEESEV 5705 L G + P +K I F G + V G P S G+ + + Sbjct: 1012 GLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPS-GVPGQPGSPGLPGQKGDKGDPGI 1070 Query: 5706 KLKKSKIKMPKFNFSKPKGKGGVTGSP-EASISGSKGD 5742 S I +P PKG+ G+ G P I GS GD Sbjct: 1071 ----SSIGLP--GLPGPKGEPGLPGYPGNPGIKGSVGD 1102 Score = 67.4 bits (163), Expect = 4e-10 Identities = 229/922 (24%), Positives = 316/922 (34%), Gaps = 190/922 (20%) Query: 4663 PGFKGE-GPDVDVNLPKAD--------IDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPE 4713 PG G G D DV LP + G K + +P + + GP GPK Sbjct: 665 PGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPP----GPK----- 715 Query: 4714 MSIKAPKISMPDIDLNLKGPKVKGDVDVTLPKVEGDLKGPEADIKGPKVDINTPDVDVHG 4773 P I P G + + P GP+ + P + G Sbjct: 716 --------GFPGIPGPPGAPGTPGRIGLEGPPGPPGFPGPKGE----------PGFALPG 757 Query: 4774 PDWHLKMPKVKMPKFSMPGFKGE-GPDVDVSLP-------KADID-VSGPKVDVDIPDVN 4824 P +PGFKG GP D P + +D + GPK DV Sbjct: 758 PPGPP----------GLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV------ 801 Query: 4825 IEGPDAKLKGPKFK--MPEINIKAPKISIPDVDLDLKGPKVKGDFDVSVPKVEGTLKGPE 4882 GP+ + GP +P I ++ P P + G + P + G + G + Sbjct: 802 --GPNGQ-PGPMGPPGLPGIGVQGPP----------GPPGIPGP--IGQPGLHG-IPGEK 845 Query: 4883 VDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLHLKAPKIGFSGPKLEGGEV 4942 D P LD GP + P + I P L KA GF G K GE+ Sbjct: 846 GDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPG----LPGKAGASGFPGTK---GEM 898 Query: 4943 DLKGPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKFGFGAKSPKADIKSPSLDVTVPE 5002 + GP L + S ++G D + P G K P L Sbjct: 899 GMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLP----GPTGEKGSKGEPGLPGPPGP 954 Query: 5003 AELNLETPEISVGGKGKKSKFKMPKIH-MSGPKIKAKKQGFDLNVPGGEIDASLKAPDVD 5061 + NL +G KG+K + +P I +SGPK G D PG L P Sbjct: 955 MDPNL------LGSKGEKGEPGLPGIPGVSGPKGYQGLPG-DPGQPGLSGQPGLPGPPGP 1007 Query: 5062 VNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEFDIKSPKFKAEAPLP--SPKLEGELQA 5119 P + + P K G M FP + ++ P + P SP L G+ Sbjct: 1008 KG--NPGLPGQPGLIGPPGLKGTIGDMGFPGPQ-GVEGPPGPSGVPGQPGSPGLPGQKG- 1063 Query: 5120 PDLELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGDLKGPKVQANLGAPDI----NI 5175 + P I GL P + P + +P G+ P ++ ++G P + Sbjct: 1064 ---DKGDPGISSIGL------PGLPGPKGEPGLPGYPGN---PGIKGSVGDPGLPGLPGT 1111 Query: 5176 EGLDAKVKTPSF----GISAPQ-VSIPDVNVNLKG----------------PKIKGDVPS 5214 G + P F G P+ +S P N L G P KG Sbjct: 1112 PGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQ 1171 Query: 5215 VGLEGPDVDLQGPEAKIKFPKFSMP-KIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKL 5273 G+ GP G + + P F P G+PG+ + G LP + G+ P K Sbjct: 1172 DGIPGP----AGQKGEPGQPGFGNPGPPGLPGLSGQKGDGG----LPGIPGNPGLPGPKG 1223 Query: 5274 EGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGLN-LS 5332 E PG P V GP GP+L+G P PG L Sbjct: 1224 E--------PGFH------GFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGLP 1269 Query: 5333 GVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRG-PSLQGDLA---VSGDIKCPKVSVG 5388 G G + G+G GI K N G P L G P L+GD + G+ P ++ Sbjct: 1270 GPEGPPGLPGNG----GIKGE-KGNPGQPG--LPGLPGLKGDQGPPGLQGNPGRPGLNGM 1322 Query: 5389 APDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRIS 5448 D L G P MK P PGS GP+ L GP L GP Sbjct: 1323 KGDPGLPGVPG---FPGMKGPS---GVPGS------AGPEGEPGLIGPPGPPGLPGPSGQ 1370 Query: 5449 APNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPG-IGVQGLEGNLQMPGIKSSGCDVNLP 5507 + + + P + G G G + GP GLPG G G G +PG +G P Sbjct: 1371 SIIIKGDAGPPGIPGQPGLKG-LPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDP 1429 Query: 5508 GVNVKLPTGQISGPEIKGGLKG 5529 G+ + T + GP GL+G Sbjct: 1430 GLPGQPGTRGLDGPPGPDGLQG 1451 Score = 65.1 bits (157), Expect = 2e-09 Identities = 139/512 (27%), Positives = 179/512 (34%), Gaps = 110/512 (21%) Query: 5200 NVNLKG-PKIKGDVPSVGLEGPD-------VDLQGPEAKIKFPKFSMPK--IGIPGVKME 5249 N+ L G P KG+ G++GP + GP FP K G PG+ + Sbjct: 360 NIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIP 419 Query: 5250 GGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKG- 5308 G P L+G P L GP GP + PS + P GP KG Sbjct: 420 GP--------PGLDGQPGAPG--LPGPP-GPAGPHIP-PSDEICEPGPPGPPGSPGDKGL 467 Query: 5309 ---PSLKGD----------LDASVPSMKVHAPGL-------NLSGVGG-KMQVGGDGVK- 5346 +KGD S P + PGL G G K Q G G K Sbjct: 468 QGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKG 527 Query: 5347 VPGIDATTKL-----NVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDL-SLEASEGS 5400 +PGI + G P L P ++GD G++ P GAP L L + G Sbjct: 528 LPGIPGAPGAPGFPGSKGEPGDILTFPGMKGD---KGELGSP----GAPGLPGLPGTPGQ 580 Query: 5401 IKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAP---------- 5450 LP + P+ PG +GP + L G ++ GP P Sbjct: 581 DGLPGLPGPK---GEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQ 637 Query: 5451 NVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGI----------GVQGLEGNLQMPGIKSS 5500 V N P + G G G+ GLPG G GL G +PGI S Sbjct: 638 GVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGS 697 Query: 5501 GCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGIN 5560 + +PG+ + P G P I G G G I ++GP P Sbjct: 698 KGEPGIPGIGLPGPPGPKGFPGIPG-----PPGAPGTPGRIGLEGPPGPPGFP------- 745 Query: 5561 LKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFS 5620 GPK + G + G P + +G L KG G P LD GL Sbjct: 746 --GPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLD------GL--P 795 Query: 5621 GPKVEGGVKG-----GQIGLQAPGLSVSGPQG 5647 GPK + G G G GL PG+ V GP G Sbjct: 796 GPKGDVGPNGQPGPMGPPGL--PGIGVQGPPG 825 Score = 59.7 bits (143), Expect = 8e-08 Identities = 257/1045 (24%), Positives = 345/1045 (33%), Gaps = 195/1045 (18%) Query: 4664 GFKGEGPDVDVNLPKADIDVSGPKVDVDVPDVNIEGPDAKL--KGPKFKMPEMSIKAPKI 4721 G KG+ D N +SGP +P + GP L G K + + PK Sbjct: 472 GVKGDKGDTCFNC--IGTGISGPPGQPGLP--GLPGPPGSLGFPGQKGEKGQAGATGPK- 526 Query: 4722 SMPDIDLNLKGPKVKGDVDVTLPKVEGDLKGPEADI------KGPKVDINTPDVD----V 4771 +P I P G KG DI KG K ++ +P + Sbjct: 527 GLPGIPGAPGAPGFPGS------------KGEPGDILTFPGMKGDKGELGSPGAPGLPGL 574 Query: 4772 HGPDWHLKMPKVKMPKFSMPG--FKGE-GPDVDVSLPKADIDVS----------GPKVDV 4818 G +P + PK G FKGE GP + LP ++ GP + Sbjct: 575 PGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEK 634 Query: 4819 DIPDVNIEGPDAKLKGPKFKMPEINIKAPKISIP-----DVDLDLKG-PKVKGDFDVSVP 4872 I V + GPK + + K +P D D+ L G P + G +P Sbjct: 635 GIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQ--PGLP 692 Query: 4873 KVEGTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLHLKAPKIGF 4932 + G+ P + P + GP P + P P +IG Sbjct: 693 GIPGSKGEPGI----PGIGLPGPPGPKGFPGIPGPPGAPGTPG-------------RIGL 735 Query: 4933 SGPKLEGGEVDLKGPKVEAPSLDVHMDSPDINIEGPDVK--IPKFKKPKFGFGAKSPKAD 4990 GP G GPK E P + GP +P FK GA PK D Sbjct: 736 EGPP---GPPGFPGPKGE----------PGFALPGPPGPPGLPGFK------GALGPKGD 776 Query: 4991 IKSPSLDVTVPEAELN-LETPEISVGGKGKKSKFKMPKIHMSGPKIKAKKQGFDLNVPGG 5049 P L+ L P+ VG G+ P + P I + +PG Sbjct: 777 RGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGL----PGIGVQGPPGPPGIPGP 832 Query: 5050 EIDASLKAPDVDVNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEFDIKSPKFKAEAPLP 5109 L + GP +DV P ++ G P SP +A Sbjct: 833 IGQPGLHGIPGEKGDPGPPG---LDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS 889 Query: 5110 S-PKLEGEL-----QAPDLELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGDL--KG 5161 P +GE+ P L +P ++ P +K D P + G KG Sbjct: 890 GFPGTKGEMGMMGPPGPPGPLGIPG--------RSGVPGLKGDDGLQGQPGLPGPTGEKG 941 Query: 5162 PKVQANLGAP----DINIEGLDAKVKTPSF----GISAP-----------------QVSI 5196 K + L P D N+ G + P G+S P Q + Sbjct: 942 SKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGL 1001 Query: 5197 PDV-----NVNLKG-------PKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIP 5244 P N L G P +KG + +G GP ++GP P G+P Sbjct: 1002 PGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQ-GVEGPPGPSGVPG-QPGSPGLP 1059 Query: 5245 GVKMEGGGAEVHA-QLPSLEGDLRGPDVKLEGPDVSLKGPGVD--LPSVNLSMPKVSGPD 5301 G K + G + + LP L G P + + +KG D LP + + P Sbjct: 1060 GQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPG 1119 Query: 5302 LDLNLKGPSLKGDLDASVPSMKVHAPGLN--LSGVGGKMQVGGDGVK-VPGID-----AT 5353 L P G S P PG + G G Q G G K PG D A Sbjct: 1120 LPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAG 1179 Query: 5354 TKLNVGAPDVTLRGP-SLQGDLAVSGDIKCPKVSVGAPDLSLEASE-GSIKLPKMKLPQF 5411 K G P GP L G GD P + G P L E G P ++ P Sbjct: 1180 QKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIP-GNPGLPGPKGEPGFHGFPGVQGPPG 1238 Query: 5412 GISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPK-VKGSLGATGE 5470 +PG L P G PG L GP EGP + G+ G GE Sbjct: 1239 PPGSPGPALEGPKGNPGPQGPPGRPGFQ-GLPGP-----------EGPPGLPGNGGIKGE 1286 Query: 5471 IKGPTVGG--GLPGI----GVQGLEGNLQMPGIKSSGCDVNLPGV----NVKLPTG--QI 5518 P G GLPG+ G GL+GN PG+ D LPGV +K P+G Sbjct: 1287 KGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGS 1346 Query: 5519 SGPEIKGGLKG--SEVGFHG-AAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGG 5575 +GPE + GL G G G + I +KG A P L GP +G + G Sbjct: 1347 AGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGP--QGPQGLPGP 1404 Query: 5576 VSAPDISLGEGHLSVKGSGGEWKGP 5600 P G G+GG P Sbjct: 1405 TGPPGDPGRNGLPGFDGAGGRKGDP 1429 Score = 55.5 bits (132), Expect = 2e-06 Identities = 142/508 (27%), Positives = 191/508 (37%), Gaps = 81/508 (15%) Query: 209 PSGSGAASPTGSAVDIRAGAISASGPELQGA-GHSKLQVTMPGIKVGGSGVNVNAKGLDL 267 P G G P G I+ A + P + G G +T PG K G G N G D+ Sbjct: 622 PPGFGPPGPVGEK-GIQGVAGNPGQPGIPGPKGDPGQTITQPG-KPGLPG-NPGRDG-DV 677 Query: 268 GGRGGVQVPAVDISSSLGGRAVEVQGPSLE-SGDHGKIKFPTMKVPKFGVSTGREGQTPK 326 G G +P + G E P + G G FP + P G G + Sbjct: 678 GLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPP-----GAPGTPGR 732 Query: 327 AGLRVSAPEVSVGHKG--GKPGLTIQAPQLEVSVPSANIEGLEGKLKGPQITGPSLEGDL 384 GL P G G G+PG + P +P G +G L GP +GD Sbjct: 733 IGLE--GPPGPPGFPGPKGEPGFALPGPPGPPGLP-----GFKGAL------GP--KGDR 777 Query: 385 GLKGAK-PQGHIGVDASAPQIGGSI-----TGPSVEVQAPDIDVQGPGSKLNVPKM--KV 436 G G P G G+D P G + GP P I VQGP +P + Sbjct: 778 GFPGPPGPPGRTGLDG-LPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQP 836 Query: 437 PKFSVSGAKGEE--TGIDVTLPTGE---VTVPGVSGDVSLPEIATGGLEGK-----MKGT 486 + G KG+ G+DV P GE +PG G + P + GL GK GT Sbjct: 837 GLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPP--GSPGLPGKAGASGFPGT 894 Query: 487 KVKTPEMIIQKPKISMQDVDLSLGSPKLKGDIKVSAPGVQGD--VKGPQVALKGSRVDIE 544 K + M P + + G P LKGD G+QG + GP KGS+ + Sbjct: 895 KGEMGMMGPPGPPGPL-GIPGRSGVPGLKGD-----DGLQGQPGLPGP-TGEKGSKGEPG 947 Query: 545 TPNLEGTLTGPRLGS--PSGKTGTCRISMSEVDLNVAAPKVKGGV--DVTLPRVEGKVKV 600 P G + LGS G+ G I V+ PK G+ D P + G+ + Sbjct: 948 LPGPPGPMDPNLLGSKGEKGEPGLPGIP------GVSGPKGYQGLPGDPGQPGLSGQPGL 1001 Query: 601 PEVDVRGPKVDVSAPDVEAHGPEWNLKMPKMK--MPTFSTPGAKG-EGPDVHMTLP--KG 655 P GPK + P G + P +K + PG +G EGP +P G Sbjct: 1002 P--GPPGPKGNPGLP-----GQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPG 1054 Query: 656 DISISGPKVNVEAPDVNLEGLGGKLKGP 683 + G K + P ++ GL G L GP Sbjct: 1055 SPGLPGQKGDKGDPGISSIGLPG-LPGP 1081 Score = 54.3 bits (129), Expect = 4e-06 Identities = 224/889 (25%), Positives = 316/889 (35%), Gaps = 167/889 (18%) Query: 2489 IRGPKVDVNAPDVQAPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDI 2548 ++GP P ++ + M + PK + PG+ GP LP I GP + Sbjct: 142 LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGN-PGYP--GPPGIQGLP-GPTGIPGP-IGP 196 Query: 2549 EGPDVNIEGPEGK--LKGPKLKMPEMNIKAPKISMPDFDLHLKGP--------KVKGDVD 2598 GP + GP G L GPK M +N + PK + L +GP + K +D Sbjct: 197 PGPP-GLMGPPGPPGLPGPKGNMG-LNFQGPKGEKGEQGL--QGPPGPPGQISEQKRPID 252 Query: 2599 VSLPKVEGDLKG---------------PEVDIKGPKVDINAPDV-GVQGPDWHLKMPKVK 2642 V K + L G P KG K + P G G D P + Sbjct: 253 VEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIP 312 Query: 2643 -MPKFSMPGFKGE-GPDGDVKLPKADIDVSGPK-VDIEGPDVNIE-GPEGKLKGPKFKMP 2698 +P PG+ GE G DG+ K K D GP + I P I G +G + P Sbjct: 313 GLP--GDPGYPGEPGRDGE-KGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGE 369 Query: 2699 EMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPK-------VEGDLKGPEVDIKGPK-VDI 2750 + P I P L GP + P +GD P + I GP +D Sbjct: 370 KGERGFPGIQGPP---GLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG 426 Query: 2751 DAPDVDVHGPDWHLKMPKIKMPKISMPGFKGE-GPDVDVNLPKADIDVSGPKVDV--ECP 2807 + GP +I PG G G D L + + V G K D C Sbjct: 427 QPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGL-QGEQGVKGDKGDTCFNCI 485 Query: 2808 DVNIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPK-IKGDVDVTGPKVEGDLKG 2866 I GP G+ P P P TGPK + G G KG Sbjct: 486 GTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKG 545 Query: 2867 PEVDL------KGPKVDIDVPDV----NVQGPDWHLKMPKMKMPKFSMPG--FKAE-GPE 2913 D+ KG K ++ P + G +P + PK G FK E GP Sbjct: 546 EPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPP 605 Query: 2914 VDVNLPKADVDVSG---PKVDVEGP--DVNIEGPEGK-----LKGPKFKMPEMNIKAPKI 2963 + LP ++ P GP + I+G G + GPK P I P Sbjct: 606 GNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGIPGPKGD-PGQTITQPGK 664 Query: 2964 P-MP-----DFDLHLKG-PKVKGDVDI-SLPKVEGDLKGPEVDIRGPQVDIDVPDV---- 3011 P +P D D+ L G P + G + +P +G+ P + + GP P + Sbjct: 665 PGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPP 724 Query: 3012 ---------GVQGPDWHLKMPKVK-MPKFSMPG---------FKGE-GPDVDVNLP---- 3047 G++GP P K P F++PG FKG GP D P Sbjct: 725 GAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPG 784 Query: 3048 ---KADLD-VSGPKVDIDVPDVNIEGPEGKLKGPKFK--MPEMNIKAPKISMPDIDLNLK 3101 + LD + GPK D+ GP G+ GP +P + ++ P P I + Sbjct: 785 PPGRTGLDGLPGPKGDV--------GPNGQ-PGPMGPPGLPGIGVQGPP-GPPGIPGPIG 834 Query: 3102 GPKVKGDMDVSLPKVEGDMKVPDVDIKGPKVDINAPDV-DVQGPDWHLKMPKI--KMPKI 3158 P + G +P +GD P +D+ GP + +P + GP P + K Sbjct: 835 QPGLHG-----IPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS 889 Query: 3159 SMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPK 3218 PG KGE + P L + G VP ++G D L+G P Sbjct: 890 GFPGTKGEMGMMGPPGPPGPLGIPGRS---GVP--GLKGDDG-LQG-----------QPG 932 Query: 3219 ISMPDLDLNLKG----PKMKGEVDVSLANVEGDLKGPAL----DIKGPK 3259 + P + KG P G +D +L +G+ P L + GPK Sbjct: 933 LPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPK 981 Score = 51.2 bits (121), Expect = 3e-05 Identities = 199/836 (23%), Positives = 285/836 (34%), Gaps = 207/836 (24%) Query: 2520 MPGFKAEGPEVDVNL---PKADVDISGPK--VDIEGPDVNIEGPEGKLKGPKLKMPE--M 2572 +PG K E + ++ PK + GP + GP I GP G P L P Sbjct: 151 IPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGP-TGIPGPIGPPGPPGLMGPPGPP 209 Query: 2573 NIKAPKISMPDFDLHLKGPK-VKGDVDVSLPKVE----GDLKGPEVDIKGPKVDINAP-D 2626 + PK +M L+ +GPK KG+ + P + K P +D++ K D P D Sbjct: 210 GLPGPKGNM---GLNFQGPKGEKGEQGLQGPPGPPGQISEQKRP-IDVEFQKGDQGLPGD 265 Query: 2627 VGVQGPDWHLKMPKVKMPKFSMPGFKGE----GPDGDVKLPKADIDVSGPKVDIEGPDVN 2682 G GP P ++ P G KGE G G P D + P + D Sbjct: 266 RGPPGP------PGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPG 319 Query: 2683 IEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKV----KGDVDV-SLPKVEGDLK 2737 G G+ G K + + P P + + G + KG++ + LP +G+ Sbjct: 320 YPGEPGR-DGEKGQKGDTGPPGP----PGLVIPRPGTGITIGEKGNIGLPGLPGEKGERG 374 Query: 2738 GPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKADIDV 2797 P I+GP P V GP PGF GE Sbjct: 375 FP--GIQGPPGLPGPPGAAVMGPP-------------GPPGFPGE--------------- 404 Query: 2798 SGPKVDVECPDVNIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTG 2857 G K D P ++I GP G P P + P GP I ++ Sbjct: 405 RGQKGDEGPPGISIPGPPGLDGQPG---------APGLPGPP---GPAGPHIPPSDEICE 452 Query: 2858 PKVEGDLKGP-------EVDLKGPKVD--IDVPDVNVQGPDWHLKMPKMKMPKFSM--PG 2906 P G P E +KG K D + + GP +P + P S+ PG Sbjct: 453 PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPG 512 Query: 2907 FKAEGPEVDVNLPKADVDVSG-------PKVDVEGPDV----NIEGPEGKLKGPKFK-MP 2954 K E + PK + G P E D+ ++G +G+L P +P Sbjct: 513 QKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLP 572 Query: 2955 EMNIKAPKIPMPDFDLHLKGPKVK-GDVDIS-------------LPKVEGDLKGPEVDIR 3000 + P P D L GPK + G + LP G + P Sbjct: 573 GL----PGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPP 628 Query: 3001 GPQVDIDVPDVGVQGPDWHLKMPKVKMPK------FSMPGFKG----EGPDVDVNLPKAD 3050 GP V + G+QG + P + PK + PG G G D DV LP Sbjct: 629 GP-----VGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDP 683 Query: 3051 --------LDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKG 3102 + G K + +P + + GP G P P P + L+G Sbjct: 684 GLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPG------RIGLEG 737 Query: 3103 PKVKGDMDVSLPKVEGDMKVPDVDIKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISMPG 3162 P P G P + GP GP +PG Sbjct: 738 PP-------GPPGFPGPKGEPGFALPGPP-----------GPP-------------GLPG 766 Query: 3163 FKGE-GPEVDVNLP-------KADLD-VSGPKVDVDVPDVNIEGPDAKLKGPKFK--MPE 3211 FKG GP+ D P + LD + GPK DV GP+ + GP +P Sbjct: 767 FKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV--------GPNGQ-PGPMGPPGLPG 817 Query: 3212 MNIKAPKISMPDLDLNLKGPKMKGEVDVSLANVEGDLKGPALDIKGPKIDVDAPDI 3267 + ++ P P + + P + G + +GD P LD+ GP + +P I Sbjct: 818 IGVQGPP-GPPGIPGPIGQPGLHG-----IPGEKGDPGPPGLDVPGPPGERGSPGI 867 Score = 47.4 bits (111), Expect = 4e-04 Identities = 168/698 (24%), Positives = 247/698 (35%), Gaps = 144/698 (20%) Query: 3500 KGDINIEGPSMNIEGPDLNVEGPEGGLKGPKFKMPDMNIKAPKISMPDIDLNLKGPKVKG 3559 KGD EGP P +++ GP G D AP + P GP + Sbjct: 408 KGD---EGP------PGISIPGPPG---------LDGQPGAPGLPGPP---GPAGPHIPP 446 Query: 3560 DVDISLPKLEGDLKGP-------EVDIKGPKVD--INAPDVDVHGPDWHLKMPKVKMPKF 3610 +I P G P E +KG K D N + GP +P + P Sbjct: 447 SDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPG 506 Query: 3611 SM--PGFKGEGPEVDVTLPKADIDISGPNVDVDVPDVNIEGPDAK----LKGPKFKMPEM 3664 S+ PG KGE + T PK I G P E D +KG K ++ Sbjct: 507 SLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSP 566 Query: 3665 NIKA----PKISMPDFDLNLKGPKMKGDVVV-----------SLPKVEGDLKGPEVDIKG 3709 P D L GPK + + LP + G++ G Sbjct: 567 GAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFG 626 Query: 3710 PKVDIDTPDIN-IEGSEGK--FKGPKFKIPEMHLKAPKISMP-----DIDLNLKG-PKVK 3760 P + I + G+ G+ GPK + + K +P D D+ L G P + Sbjct: 627 PPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP 686 Query: 3761 GDVDV-SLPKMEGDLKGPEVDIKGPKVDINAPDVD-------------VQGPDWHLKMPK 3806 G + +P +G+ P + + GP P + ++GP P Sbjct: 687 GQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG 746 Query: 3807 VK-MPKFSMPG---------FKGE-GPDVDVNLP-------KADLD-VSGPKVDIDVPDV 3847 K P F++PG FKG GP D P + LD + GPK D+ Sbjct: 747 PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV----- 801 Query: 3848 NIEGPEGKLKGPKFK--MPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMQVP 3905 GP G+ GP +P + ++ P P I + P + G +P +GD P Sbjct: 802 ---GPNGQ-PGPMGPPGLPGIGVQGPP-GPPGIPGPIGQPGLHG-----IPGEKGDPGPP 851 Query: 3906 DLDIKGPKVDINAPDVDVR----GPDWHLKMPKIKMPKISMPGFKGEGPEVDVNLPKADL 3961 LD+ GP + +P + GP +P K PG KGE + P L Sbjct: 852 GLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPG-KAGASGFPGTKGEMGMMGPPGPPGPL 910 Query: 3962 DVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDV 4021 + G VP ++G D L+G P + P + KG + Sbjct: 911 GIPGRS---GVP--GLKGDDG-LQG-----------QPGLPGPTGEKGSKG-------EP 946 Query: 4022 SLPKMEGDLKAPEVDIKGPKVDIDAPDV-DVHGPDWHLKMP-KVKMPKFS-MPGFKG-EG 4077 LP G + + KG K + P + V GP + +P P S PG G G Sbjct: 947 GLPGPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPG 1006 Query: 4078 PEVDVNLPKADIDVSGPKVDIDTPDIDIHGPEGKLKGP 4115 P+ + LP + P + D+ GP+G ++GP Sbjct: 1007 PKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQG-VEGP 1043 Score = 47.0 bits (110), Expect = 6e-04 Identities = 129/480 (26%), Positives = 165/480 (34%), Gaps = 80/480 (16%) Query: 5242 GIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPD--VSLKGP-GVDLPSVNLSMPKVS 5298 GIPG+K E G + + LP +G+ P GP L GP G+ P P + Sbjct: 150 GIPGMKGEPGSI-IMSSLPGPKGNPGYP-----GPPGIQGLPGPTGIPGPIGPPGPPGLM 203 Query: 5299 GPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLSGVGGKMQVGGDGVK----VPGIDATT 5354 GP L GP KG++ GLN G G+ G G++ PG + Sbjct: 204 GPPGPPGLPGP--KGNM------------GLNFQGPKGEK--GEQGLQGPPGPPGQISEQ 247 Query: 5355 KLNVGAP----DVTLRG-------PSLQGDLAVSGDIKCPKVSVGAPDL----SLEASEG 5399 K + D L G P ++G G K K G P + G Sbjct: 248 KRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENG 307 Query: 5400 SIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRIS-APNVDFNLEG 5458 +P + PG D KG +G PG+ + G I+ + L G Sbjct: 308 QPGIPGLPGDPGYPGEPGRDGEKGQKGD--TGPPGPPGLVIPRPGTGITIGEKGNIGLPG 365 Query: 5459 -PKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQ 5517 P KG G G I+GP G PG V G G PG + D PG+++ P G Sbjct: 366 LPGEKGERGFPG-IQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGL 424 Query: 5518 ISGPEIKG--GLKGSEVGFHGAAPDISVKGPAFNMASP--------------ESDFGINL 5561 P G G G + +I GP SP + D N Sbjct: 425 DGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNC 484 Query: 5562 KGPKIKGGADVSG--GVSAPDISLG-EGHLSVKGSGGEW--KG----PQVSSALNLDTSK 5612 G I G G G+ P SLG G KG G KG P A SK Sbjct: 485 IGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSK 544 Query: 5613 FAGG--LHFSGPKVEGGVKGGQIGLQAPGLSVSGPQGHLESGSGKVTFPKMKIPKFTFSG 5670 G L F G K + G G PGL + Q L G PK + TF G Sbjct: 545 GEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPG----PKGEPGGITFKG 600 Score = 45.4 bits (106), Expect = 0.002 Identities = 278/1149 (24%), Positives = 398/1149 (34%), Gaps = 265/1149 (23%) Query: 2025 IKGPKMD--IDAPDVDVHGPDWHLKMPKMKMPKFSM--PGFKAE-------GPEVDVNLP 2073 +KG K D + + GP +P + P S+ PG K E GP+ +P Sbjct: 473 VKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLPGIP 532 Query: 2074 KADVVVSGPKVDVEVPDV----SLEGPEGKLKGPKLK-MPEMHFKAPKISMPDVDLHLKG 2128 A P E D+ ++G +G+L P +P + + +P L G Sbjct: 533 GAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLPG----LPG 588 Query: 2129 PK-------VKGDV----DVSLPKLEGDL----------TGPSVDVEVPDVELECPDAKL 2167 PK KG+ + LP L G++ GP + + V + Sbjct: 589 PKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPGI 648 Query: 2168 KGPKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMDV-SVPKVEGEMKVPDVDIRGPKVD 2226 GPK + + K +P P GD+ + P + G+ +P + G K + Sbjct: 649 PGPKGDPGQTITQPGKPGLPG------NPGRDGDVGLPGDPGLPGQPGLPGIP--GSKGE 700 Query: 2227 IDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKGEGPEVDVNLPKADVDVSGPKVDVEVPDV 2286 P + + GP P + P PG G + + P GPK + P Sbjct: 701 PGIPGIGLPGPPGPKGFPGIPGP----PGAPGTPGRIGLEGPPGPPGFPGPKGE---PGF 753 Query: 2287 SLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVDVSAPK-------LEG 2339 +L GP G P FK GPK GD P L+G Sbjct: 754 ALPGPPGPPGLPGFK------------------GALGPK--GDRGFPGPPGPPGRTGLDG 793 Query: 2340 ELKGPELDV-----KGPKLDADMPEVAVEGPNGKWKTPKFKMPDMHFKAPKISMPDLDLH 2394 L GP+ DV GP +P + V+GP G P I P Sbjct: 794 -LPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGP---------------PGIPGP----- 832 Query: 2395 LKSPKAKGEVDVDVPKLEGDLKGPHVDVSGPDIDIEGPEGKLKGPKFKMPDMHFKAPNIS 2454 + P L G + G D P +D+ GP G+ P AP Sbjct: 833 -----------IGQPGLHG-IPGEKGDPGPPGLDVPGPPGERGSPGIP------GAPGPI 874 Query: 2455 MPDVDLNLKG-------PKIKGDVD-VSVPEVEGKLEVPDMNIRGPKVDVNAPDVQAPDW 2506 P L G P KG++ + P G L +P + P ++ D Sbjct: 875 GPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRS--------GVPGLKGDDG 926 Query: 2507 HLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDIEGP-DVNIEGPEGKLKGP 2565 P +PG E K + + GP GP D N+ G +G+ P Sbjct: 927 LQGQP-------GLPGPTGEKGS------KGEPGLPGP----PGPMDPNLLGSKGEKGEP 969 Query: 2566 KLKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGD--LKGPEVDIKGPKVDIN 2623 L P +S P L G D P + G L GP GPK + Sbjct: 970 GLP------GIPGVSGPKGYQGLPG-------DPGQPGLSGQPGLPGP----PGPKGNPG 1012 Query: 2624 AP-DVGVQGPDWHLKMPKVK--MPKFSMPGFKG-EGPDGDVKLP--KADIDVSGPKVDIE 2677 P G+ GP P +K + PG +G EGP G +P + G K D Sbjct: 1013 LPGQPGLIGP------PGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKG 1066 Query: 2678 GPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDV-DVSLPKVEG-- 2734 P ++ G G L GPK P + P +KG V D LP + G Sbjct: 1067 DPGISSIGLPG-LPGPK-------------GEPGLPGYPGNPGIKGSVGDPGLPGLPGTP 1112 Query: 2735 DLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKIKMPKISMPGFKGE-GPDVDVNLPKA 2793 KG P + GP + +P P + G G+ GP + P Sbjct: 1113 GAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGP-VGGGGHPGQPGPPGEKGKPGQ 1171 Query: 2794 DIDVSGPKVDVECPDVNIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDV 2853 D + GP G +G+ P F P P +S D L P I G+ Sbjct: 1172 D-GIPGP-----------AGQKGEPGQPGFGNPGPP-GLPGLSGQKGDGGL--PGIPGNP 1216 Query: 2854 DVTGPKVEGDLKG-PEVDLKGPKVDIDVPDVNVQGPDWHLKMPKMKMPKFSMPGFKA-EG 2911 + GPK E G P V +GP P ++GP + P + P PGF+ G Sbjct: 1217 GLPGPKGEPGFHGFPGV--QGPPGPPGSPGPALEGPKGN---PGPQGPP-GRPGFQGLPG 1270 Query: 2912 PEVDVNLPKADVDVSGPKVDVEGPDV-------NIEGPEGKLKGPKFKMPEMNIKA-PKI 2963 PE LP + + G K + P + +GP G L+G + +K P + Sbjct: 1271 PEGPPGLP-GNGGIKGEKGNPGQPGLPGLPGLKGDQGPPG-LQGNPGRPGLNGMKGDPGL 1328 Query: 2964 P-MPDFDLHLKGPKVKGDVDISLPKVEGDLKGP--EVDIRGPQ-----VDIDVPDVGVQG 3015 P +P F +KGP G + P+ E L GP + GP + D G+ G Sbjct: 1329 PGVPGFP-GMKGP--SGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPG 1385 Query: 3016 PDWHLKMPKVKMPKFSMPGFKGEGPDVDVN-LPKADLDVSGPKVDIDVPDV----NIEGP 3070 +P + P+ +PG G D N LP D G K D +P ++GP Sbjct: 1386 QPGLKGLPGPQGPQ-GLPGPTGPPGDPGRNGLPGFD-GAGGRKGDPGLPGQPGTRGLDGP 1443 Query: 3071 EGK--LKGP 3077 G L+GP Sbjct: 1444 PGPDGLQGP 1452 Score = 42.4 bits (98), Expect = 0.014 Identities = 164/684 (23%), Positives = 233/684 (34%), Gaps = 149/684 (21%) Query: 291 VQGPSLESGDHGKIKFPTMKVPKFGVSTGREGQTPKAGLR-VSAPEVSVGHKG-----GK 344 +QG GD G F + TG G + GL + P S+G G G+ Sbjct: 467 LQGEQGVKGDKGDTCFNC-------IGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQ 519 Query: 345 PGLTIQAPQLEVSVPSA----NIEGLEGKLKGPQITGPSLEGDLGLKGAK-PQGHIGVDA 399 G T P+ +P A G +G+ G +T P ++GD G G+ G G+ Sbjct: 520 AGAT--GPKGLPGIPGAPGAPGFPGSKGE-PGDILTFPGMKGDKGELGSPGAPGLPGLPG 576 Query: 400 SAPQIG-GSITGPSVEV--------QAPDIDVQGPGSKLNVPKMKVPKFSVSGAKGEETG 450 + Q G + GP E + P + PG N+ M P F G GE+ Sbjct: 577 TPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGI 636 Query: 451 IDVTLPTGEVTVPGVSGD--VSLPEIATGGLEGKMKGTKVKTPEMIIQKPKISMQDVDLS 508 V G+ +PG GD ++ + GL G +D D+ Sbjct: 637 QGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGN------------------PGRDGDVG 678 Query: 509 L-GSPKLKGDIKVSAPGVQGDVKGPQVALKGSRVDIETPNLEGTLTGPRLGSPSGKTGT- 566 L G P L G + PG+ G P + I P G P + P G GT Sbjct: 679 LPGDPGLPG--QPGLPGIPGSKGEPGIP------GIGLPGPPGPKGFPGIPGPPGAPGTP 730 Query: 567 CRISMSEVDLNVAAPKVKGGVDVTLPRVEGKVKVPEV-DVRGPKVDVSAPDVEAHGPEWN 625 RI + P KG LP G +P GPK D P GP Sbjct: 731 GRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFP-----GP--- 782 Query: 626 LKMPKMKMPTFSTPGAKGEGPDVHMTLPKGDISISGPKVNVEAPDVNLEGLGGKLKGPDV 685 PG G + PKGD+ +G + P L G+G ++GP Sbjct: 783 -------------PGPPGRTGLDGLPGPKGDVGPNGQPGPMGPP--GLPGIG--VQGPP- 824 Query: 686 KLPDMSVKTPKISMPDVDLHVKGTKVKGEYDVTVPKLEGELKGPKVDIDAPDVDVHGPDW 745 P I P + P L G + G K D P +DV GP Sbjct: 825 -------GPPGIPGP----------------IGQPGLHG-IPGEKGDPGPPGLDVPGPPG 860 Query: 746 HLKMPKMKMPKFSVPGFKAE-GPEVDVNLP-----------KADVDISGPKIDVTAPDVS 793 P +PG GP LP K ++ + GP P Sbjct: 861 ERGSP-------GIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGP----PGPPGP 909 Query: 794 IEEPEGKLKGPKFKMPEMNIKVPKISMPDVDLHLKG-PNVKGEYDVTMPKVESEIKVPDV 852 + P G+ P K + P + P + KG P + G P + + Sbjct: 910 LGIP-GRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNL--------L 960 Query: 853 ELKSAKMDIDVPDVE-VQGPDWHLKMP-KMKMPKFS-MPGFKA-EGPEVDVNLPKADVDI 908 K K + +P + V GP + +P P S PG GP+ + LP I Sbjct: 961 GSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLI 1020 Query: 909 SGPKVGVEVPDVNIEGPEGKLKGP 932 P + + D+ GP+G ++GP Sbjct: 1021 GPPGLKGTIGDMGFPGPQG-VEGP 1043 Score = 38.1 bits (87), Expect = 0.26 Identities = 254/1033 (24%), Positives = 358/1033 (34%), Gaps = 243/1033 (23%) Query: 2939 IEGPEGKLKGPKFKMPEMNIKAPKIPMPDFDLHLKGPKVKGDVDISLPKVEGDLKGPEVD 2998 ++GP G P K +I +P P + GP P ++G L GP Sbjct: 142 LQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGP----------PGIQG-LPGP-TG 189 Query: 2999 IRGPQVDIDVPDV-GVQGPDWHLKMPKVKMP-KFSMP-GFKGE-------GPDVDVNLPK 3048 I GP P + G GP L PK M F P G KGE GP ++ K Sbjct: 190 IPGPIGPPGPPGLMGPPGPPG-LPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQK 248 Query: 3049 ADLDVSGPKVDIDVPD-------VNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLK 3101 +DV K D +P I GP G G K + E + K P D Sbjct: 249 RPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQG-EPGKRGKPGKDGENG 307 Query: 3102 GPKVKGDMDVSLPKVEGDMKVPDVD-IKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISM 3160 P + G LP G P D KG K D P GP P + +P+ Sbjct: 308 QPGIPG-----LPGDPGYPGEPGRDGEKGQKGDTGPP-----GP------PGLVIPRPGT 351 Query: 3161 PGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKIS 3220 GE + ++ LP + G K + P I+GP L GP P + P Sbjct: 352 GITIGE--KGNIGLP----GLPGEKGERGFP--GIQGPPG-LPGP----PGAAVMGPP-- 396 Query: 3221 MPDLDLNLKGPKMKGEVDVSLANVEGDLKGPALDIKGPK-IDVDAPDIDIHGPDAKLKGP 3279 P GE +GD P + I GP +D + GP GP Sbjct: 397 --------GPPGFPGE-----RGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPA-GP 442 Query: 3280 KLKMPDMHVNMPKISMPEIDLNLKGSKLKGDVDVSGPKLEGDIKAPSLDIKGPEVDVSGP 3339 + P + P P KG L+G+ V G K + I GP P Sbjct: 443 HIP-PSDEICEPGPPGPPGSPGDKG--LQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLP 499 Query: 3340 KLNIEGKSKKSRFKLPKFNFSGSKVQTPEVDVKGKKPDIDITGPKVDINAPDVEVQGKVK 3399 L S F G K G+K TGPK P Sbjct: 500 GLPGPPGS---------LGFPGQK---------GEKGQAGATGPKGLPGIPGAPGAPGFP 541 Query: 3400 GSKFKMPFLSISSPKVSMPDVELNLKSPKVKGDLDIAGPNLEGDFKGPKVDIKAPEVNLN 3459 GSK + GD+ + P ++GD K ++ +P Sbjct: 542 GSKGE-------------------------PGDI-LTFPGMKGD----KGELGSP----G 567 Query: 3460 APDVD-VHGPDWNLKMPKMKMPKFSVSGL--KAE-GPDVAVDLP--KGDINIEGP-SMNI 3512 AP + + G +P + PK G+ K E GP LP G+I GP Sbjct: 568 APGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGP 627 Query: 3513 EGP--DLNVEGPEG-----GLKGPKFKMPDMNIKAP-KISMP-----DIDLNLKG-PKVK 3558 GP + ++G G G+ GPK P I P K +P D D+ L G P + Sbjct: 628 PGPVGEKGIQGVAGNPGQPGIPGPKGD-PGQTITQPGKPGLPGNPGRDGDVGLPGDPGLP 686 Query: 3559 GDVDI-SLPKLEGDLKGPEVDIKGPKVDINAPDVD-------------VHGPDWHLKMPK 3604 G + +P +G+ P + + GP P + + GP P Sbjct: 687 GQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG 746 Query: 3605 VK-MPKFSMPG---------FKGE-GPEVDVTLP-------KADID-ISGPNVDVDVPDV 3645 K P F++PG FKG GP+ D P + +D + GP DV Sbjct: 747 PKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV----- 801 Query: 3646 NIEGPDAKLKGPKFK--MPEMNIKAPKISMPDFDLNLKGPKMKGDVVVSLPKVEGDLKGP 3703 GP+ + GP +P + ++ P P + P + G +P +GD P Sbjct: 802 ---GPNGQ-PGPMGPPGLPGIGVQGPP-GPPGIPGPIGQPGLHG-----IPGEKGDPGPP 851 Query: 3704 EVDIKGPKVDIDTPDI----------NIEGSEGK-----FKGPKFKIPEMHLKAP----- 3743 +D+ GP + +P I G GK F G K ++ M P Sbjct: 852 GLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLG 911 Query: 3744 ---KISMPDI--DLNLKG-PKVKGDVDVSLPKMEGDLKGPE-------VDIKGPKVDINA 3790 + +P + D L+G P + G K E L GP + KG K + Sbjct: 912 IPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPGL 971 Query: 3791 PDV-DVQGPDWHLKMP-KVKMPKFS-MPGFKG-EGPDVDVNLPKADLDVSGPKVDIDVPD 3846 P + V GP + +P P S PG G GP + LP + P + + D Sbjct: 972 PGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGD 1031 Query: 3847 VNIEGPEGKLKGP 3859 + GP+G ++GP Sbjct: 1032 MGFPGPQG-VEGP 1043 Score = 37.0 bits (84), Expect = 0.58 Identities = 202/844 (23%), Positives = 288/844 (34%), Gaps = 216/844 (25%) Query: 3760 KGDVDV-SLPKMEGDLKGPEVDIKGPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFK 3818 KG++ + LP +G+ P I+GP P V GP PGF Sbjct: 358 KGNIGLPGLPGEKGERGFP--GIQGPPGLPGPPGAAVMGPP-------------GPPGFP 402 Query: 3819 GEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDI 3878 GE G K D P ++I GP G P AP + P Sbjct: 403 GE---------------RGQKGDEGPPGISIPGPPGLDGQPG---------APGLPGPP- 437 Query: 3879 DLNLKGPKVKGDMDVSLPKVEGDMQVP-------DLDIKGPKVD--INAPDVDVRGPDWH 3929 GP + ++ P G P + +KG K D N + GP Sbjct: 438 --GPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQ 495 Query: 3930 LKMPKIKMP--KISMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGP 3987 +P + P + PG KGE K +GPK +P P A Sbjct: 496 PGLPGLPGPPGSLGFPGQKGE---------KGQAGATGPKGLPGIPGA----PGA----- 537 Query: 3988 KFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKVDIDAP 4047 P F P GD+ ++ P M+GD KG AP Sbjct: 538 ----------------PGFPGSKGEP---GDI-LTFPGMKGD--------KGELGSPGAP 569 Query: 4048 DVD-VHGPDWHLKMPKVKMPKFSMPG--FKGE-GPEVDVNLP--KADIDVSGPKVDIDTP 4101 + + G +P + PK G FKGE GP + LP +I GP P Sbjct: 570 GLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGP------P 623 Query: 4102 DIDIHGPEGK--------------LKGPKFKMPDLHLKAPKISMP-----EVDLNLKG-P 4141 GP G+ + GPK + K +P + D+ L G P Sbjct: 624 GFGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDP 683 Query: 4142 KMKGDVDV-SLPKVEGDLKGPEVDIKGPKVDIDVPDVD-------------VQGPDWHLK 4187 + G + +P +G+ P + + GP P + ++GP Sbjct: 684 GLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPG 743 Query: 4188 MPKVK-MPKFSMPG---------FKGE-GPDVDVNLP-------KADLD-VSGPKVDIDV 4228 P K P F++PG FKG GP D P + LD + GPK D+ Sbjct: 744 FPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDV-- 801 Query: 4229 PDVNIEGPDAKLKGPKFK--MPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDL 4286 GP+ + GP +P + ++ P P + P + G +P +GD Sbjct: 802 ------GPNGQ-PGPMGPPGLPGIGVQGPP-GPPGIPGPIGQPGLHG-----IPGEKGDP 848 Query: 4287 KGPEVDIKGPKVDIDAPDV----DVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVTLPK 4342 P +D+ GP + +P + GP +P K PG KGE + P Sbjct: 849 GPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPG-KAGASGFPGTKGEMGMMGPPGPP 907 Query: 4343 ADIEISGPK-VDIDAPDVSIEGPDAKLKGP---KFKMPEMNIKAPKISMPDIDFNLKGPK 4398 + I G V D ++G L GP K E + P M D NL G K Sbjct: 908 GPLGIPGRSGVPGLKGDDGLQGQPG-LPGPTGEKGSKGEPGLPGPPGPM---DPNLLGSK 963 Query: 4399 -VKGDVDVSLPKVEGDLKGPEIDIKGPSLDIDTPDVN----IEGPEGKLKGPKFKMPEMN 4453 KG + LP + G + GP+ +G D P ++ + GP G P Sbjct: 964 GEKG--EPGLPGIPG-VSGPK-GYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGL 1019 Query: 4454 IKAPKISMPDFDLHLKGPK-VKGDVDVS----------LPKVESDLKGPEVDIEGPEGKL 4502 I P + D+ GP+ V+G S LP + D P + G G L Sbjct: 1020 IGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPG-L 1078 Query: 4503 KGPK 4506 GPK Sbjct: 1079 PGPK 1082 >gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] Length = 1669 Score = 72.4 bits (176), Expect = 1e-11 Identities = 181/707 (25%), Positives = 244/707 (34%), Gaps = 153/707 (21%) Query: 5103 KAEAPLP----SPKLEGELQAPDLELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGD 5158 K +A P SP L G P + LP G + +P P D P G Sbjct: 617 KGQAGFPGGPGSPGLPGPKGEPGKIVPLPG--PPGAEGLPGSPGFPGPQGDRGFPGTPGR 674 Query: 5159 LKGPKVQANLGAPDIN---------IEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIK 5209 P + +G P I ++GL + P +P N ++G K + Sbjct: 675 PGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPG-NPGVQGQKGE 733 Query: 5210 GDVPSVGLEGPDVDLQGPEAKIKFPKFSMPK--IGIPGVKMEGG--------GAEVHAQL 5259 P VGL G L+G P K IG+PGV E G G Sbjct: 734 ---PGVGLPG----LKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGP 786 Query: 5260 PSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASV 5319 P L G + P V GP PG P P +SGP P +KG+ Sbjct: 787 PGLPGSVGSPGVPGIGP------PGARGPPGGQGPPGLSGP--------PGIKGE--KGF 830 Query: 5320 PSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKL-----NVGAPDVTLRGPSLQGDL 5374 P PGL++ G G G +PGI + L GAP + P +G++ Sbjct: 831 PGF----PGLDMPGPKGDKGAQG----LPGITGQSGLPGLPGQQGAPGIP-GFPGSKGEM 881 Query: 5375 AVSGDIKCPKVS--VGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGE 5432 V G P VGAP L E + PGS GP+ Sbjct: 882 GVMGTPGQPGSPGPVGAPGLPGEKGDHGF--------------PGSS------GPRGDPG 921 Query: 5433 LKGPGVDVNLKGPRISAPNVDF-NLEGPK----VKGSLGATGEIKGPTVGGGLPGI---- 5483 LKG DV L G S VD +++G K KG +G GE KG G PG+ Sbjct: 922 LKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGE-KGSRGDPGTPGVPGKD 980 Query: 5484 ---------------GVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLK 5528 G+ G G +PG K S + LPG + I GP+ GL Sbjct: 981 GQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLP 1040 Query: 5529 GSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPK-IKGGADVSGGVSAPDISLGEGH 5587 G + GA + GP GI + G + KG ++G +P +G Sbjct: 1041 GDK----GAKGEKGQAGPP----------GIGIPGLRGEKGDQGIAGFPGSPGEKGEKGS 1086 Query: 5588 LSVKGSGGE--WKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKG--------GQIGLQA 5637 + + G G KG S + G G K + G+ G G+ GL Sbjct: 1087 IGIPGMPGSPGLKGSPGSVG-------YPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPG 1139 Query: 5638 -PGLSVSGPQGHL-ESGSGKVTFPKMKIPKFTFSGRELVGREMGVDVHFPKAEASIQAGA 5695 PG +GP G E GS + + + GR G K E A Sbjct: 1140 TPG--PTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLA 1197 Query: 5696 GDGEWEESEVKLKKSKIKMPKFNFSKPKGKGGVTGSPEASISGSKGD 5742 G + SK + P+G+ G+ GSP + G KGD Sbjct: 1198 GSPG-------IPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGD 1237 Score = 63.2 bits (152), Expect = 8e-09 Identities = 121/489 (24%), Positives = 173/489 (35%), Gaps = 84/489 (17%) Query: 249 PGIKVGGSGVNVNAKGLDLGGRGGVQVPAVDISSSLGGRAVEVQGPSLESGDHGKIKFPT 308 PG G + KG G GG P + G+ V + GP G G FP Sbjct: 603 PGPPGYGPAGPIGDKG-QAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPG 661 Query: 309 MKVPKFGVST-------GREGQTPKAGLRVSAPEVSVGHKG-----------GKPGLT-- 348 + + T G +G + G+ P G G G+PG Sbjct: 662 PQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGL 721 Query: 349 --IQAPQLEVSVPSANIEGLEGKLKGPQITG-PSLEGDLGLKGAK-------PQGHIGV- 397 Q + P + GL+G P I G P +G +G+ G P G G+ Sbjct: 722 PGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIR 781 Query: 398 -DASAPQIGGSITGPSVEVQAPDIDVQGPGSKLNVPKMKVPKFSVSGAKGEE-----TGI 451 + P + GS+ P V P +GP P + P G KGE+ G+ Sbjct: 782 GEPGPPGLPGSVGSPGVPGIGPP-GARGPPGGQGPPGLSGPP----GIKGEKGFPGFPGL 836 Query: 452 DVTLPTGEVT---VPGVSGDVSLPEIATGGLEGKMKGTKVKTPEMIIQKPKISMQDVDLS 508 D+ P G+ +PG++G LP GL G+ + P K ++ + Sbjct: 837 DMPGPKGDKGAQGLPGITGQSGLP-----GLPGQQGAPGI--PGFPGSKGEMGVMGTPGQ 889 Query: 509 LGSPKLKGDIKVSAPGVQGDV--------KGPQ--VALKGSRVDIETPNLEGTLTGPRLG 558 GSP V APG+ G+ GP+ LKG + D+ P G++ +G Sbjct: 890 PGSPG-----PVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMG 944 Query: 559 SPSGKTGTCRISMSEVDLNVAAPKVKGGVDVTLPRVEGK-VKVPEVDVRGPKVDVSAPDV 617 S G+ G + + K G D P V GK + + GPK D P + Sbjct: 945 SMKGQKGD---QGEKGQIGPIGEKGSRG-DPGTPGVPGKDGQAGQPGQPGPKGD---PGI 997 Query: 618 EAHGPEWNLKMPKMKMPTFSTPGAKGE-------GPDVHMTLPKGDISISGPKVNVEAPD 670 L PK + PG GE GP LP GD G K P Sbjct: 998 SGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLP-GDKGAKGEKGQAGPPG 1056 Query: 671 VNLEGLGGK 679 + + GL G+ Sbjct: 1057 IGIPGLRGE 1065 Score = 59.3 bits (142), Expect = 1e-07 Identities = 142/552 (25%), Positives = 194/552 (35%), Gaps = 115/552 (20%) Query: 5341 GGDGVK-VPGIDATTKLNVGAP-----------DVTLRG----PSLQGDLAVSGDIKCPK 5384 G DGV VPG T L +G P D+ L+G P G ++G P Sbjct: 504 GRDGVAGVPGPQGTPGL-IGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPG 562 Query: 5385 VSVGAPDL-SLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLK 5443 G P L + S GS+ L + P G+ PGS GP GP + K Sbjct: 563 RD-GHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRGDTGPPGPPG----YGPAGPIGDK 617 Query: 5444 GPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGI-------GVQGLEGNLQMPG 5496 G + P + P KG G + GP GLPG G +G G PG Sbjct: 618 G-QAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPG 676 Query: 5497 IKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKG--------SEVGFHGAAPDISVKGPAF 5548 + V PG+ P GP+ GL G GF+G + V+G Sbjct: 677 LPGEKGAVGQPGIGFPGP----PGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQG--- 729 Query: 5549 NMASPESDFGINLKG-------PKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQ 5601 + + G+ L G P I G G + P + G + G G P Sbjct: 730 ----QKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEP- 784 Query: 5602 VSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQAPGLSVSGPQGHLESGSGKVTFPKM 5661 L S + G+ GP G GGQ PGL SGP G ++ G FP Sbjct: 785 --GPPGLPGSVGSPGVPGIGPPGARGPPGGQ---GPPGL--SGPPG-IKGEKGFPGFP-- 834 Query: 5662 KIPKFTFSGRELVGREMGVDVHFPKAEASIQAGAG-DGEWEESEVKLKKSKIKMPKFNFS 5720 G+D+ PK + Q G G+ + ++ +P F S Sbjct: 835 -----------------GLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGS 877 Query: 5721 KPKGKGGVTGSPEASISGSKGDLKSSKASLGSLEGEAEAEASSPKGKFSLFKSKKPRHRS 5780 KG+ GV G+P GS G + + L GE KG S PR Sbjct: 878 --KGEMGVMGTP--GQPGSPGPVGAP-----GLPGE--------KGDHGFPGSSGPRGDP 920 Query: 5781 NSFSDEREFSGPSTPTGTLEFEGGEVSLEGGKVKGKHG----KLKFGTFGGLGSK-SKGH 5835 D+ + P P G ++ G +KG+ G K + G G GS+ G Sbjct: 921 GLKGDKGDVGLPGKP-------GSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGT 973 Query: 5836 YEVTGSDDETGK 5847 V G D + G+ Sbjct: 974 PGVPGKDGQAGQ 985 Score = 58.5 bits (140), Expect = 2e-07 Identities = 120/426 (28%), Positives = 162/426 (38%), Gaps = 80/426 (18%) Query: 5203 LKGPKIKGDVPSVGLEGPDVD-----LQGPEAKIKFP----------KFSMPKIGIPGVK 5247 L GPK G V +GL G + + GP+ P + P IGIPG++ Sbjct: 1006 LPGPK--GSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLR 1063 Query: 5248 MEGGGAEVHAQLPSLEGDLRGPDVKLEGPDV----SLKG-PG-VDLPSVNLSMPKVSGPD 5301 E G + A P G+ +G + P + LKG PG V P P + G Sbjct: 1064 GEKGDQGI-AGFPGSPGE-KGEKGSIGIPGMPGSPGLKGSPGSVGYPG----SPGLPGEK 1117 Query: 5302 LDLNLKG----PSLKGDLDASVPSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLN 5357 D L G P +KG+ A +P PG G K + G DG+ PG A K Sbjct: 1118 GDKGLPGLDGIPGVKGE--AGLPG----TPGPT-GPAGQKGEPGSDGI--PG-SAGEKGE 1167 Query: 5358 VGAPDVTLRG-PSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTP 5416 G P G P +GD G++ P ++ G+P + E P Q G+ P Sbjct: 1168 PGLPGRGFPGFPGAKGDKGSKGEVGFPGLA-GSPGIPGSKGEQGFMGPPGPQGQPGL--P 1224 Query: 5417 GSDLHVNA-----KGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEI 5471 GS H +GPQ G+ PG+ + P + P +D VKG G G Sbjct: 1225 GSPGHATEGPKGDRGPQ--GQPGLPGLPGPMGPPGL--PGID------GVKGDKGNPGWP 1274 Query: 5472 KGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKG-- 5529 P V G G QG+ G PGI S D+ PGV GP+ GL+G Sbjct: 1275 GAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGV------PGFQGPKGLPGLQGIK 1328 Query: 5530 SEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGEGHLS 5589 + G G + GP P + I IKG + G P + +G Sbjct: 1329 GDQGDQGVPGAKGLPGP----PGPPGPYDI------IKGEPGLPGPEGPPGLKGLQGLPG 1378 Query: 5590 VKGSGG 5595 KG G Sbjct: 1379 PKGQQG 1384 Score = 42.4 bits (98), Expect = 0.014 Identities = 124/526 (23%), Positives = 166/526 (31%), Gaps = 127/526 (24%) Query: 5206 PKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGD 5265 P +KGD + P + L+G FP GIPG G LP L+G Sbjct: 153 PGMKGDPGEILGHVPGMLLKGERG---FP-------GIPGTPGPPG-------LPGLQGP 195 Query: 5266 LRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGP---------SLKGDLD 5316 + P GP + + LS G D + GP KGD Sbjct: 196 VGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFA 255 Query: 5317 ASVPSMKVHAPGLN-LSGVGGKMQVGGDGVK-VPGIDATTKLNVGAPD----------VT 5364 + PG + GVG K + G G + PG D K G+P + Sbjct: 256 TKGEKGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGD-KGEKGSPGFPGEPGYPGLIG 314 Query: 5365 LRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNA 5424 +GP QG+ +G P + +G L + G P + PG Sbjct: 315 RQGP--QGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGP 372 Query: 5425 KGPQVSGELKGPGV--------DVNLKGPRISAPNVDFNLEGPKVKGSLGATGEI----- 5471 G V G+ PG D G + P+ L GP GS G G+ Sbjct: 373 PGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPP--GSPGPPGQPGYTNG 430 Query: 5472 -----KGPTVGGGLPGI--------------------------------GVQGLEGNLQM 5494 GP G PGI G QG G + Sbjct: 431 IVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGF 490 Query: 5495 PGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPE 5554 PG + D LPG + + GP+ GL G P E Sbjct: 491 PGQPGAKGDRGLPG---RDGVAGVPGPQGTPGLIGQ---------------PGAKGEPGE 532 Query: 5555 SDFGINLKGPKIKGGADVSGGVSAPDISLG-EGHLSVKGSGGEWKGPQVSSALNLDTSKF 5613 F + LKG K G G++ S G +GH + G KG S L + Sbjct: 533 FYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGP----KGSPGSVGLKGERGP- 587 Query: 5614 AGGLHFSGPKVEGGVKGGQIGLQAPGLSVSGPQGHLESGSGKVTFP 5659 GG+ F G + + G G PG +GP G G+ FP Sbjct: 588 PGGVGFPGSRGDTGPPG------PPGYGPAGPIG----DKGQAGFP 623 Score = 40.0 bits (92), Expect = 0.069 Identities = 194/753 (25%), Positives = 271/753 (35%), Gaps = 132/753 (17%) Query: 2521 PGFKAEGPEVDVNLPKAD--VDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPK 2578 PGF GP+ D P + G K + P + GP G KG +M Sbjct: 657 PGFP--GPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGP-KGVDGLPGDMGPPGTP 713 Query: 2579 ISMPDFDLHLKGPKV---KGDVDVSLPKVEGDLKGPEVD-IKGPKVDINAPDVGVQGPDW 2634 P F+ P V KG+ V LP ++G P + G K I P GV G Sbjct: 714 -GRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVP--GVPGEHG 770 Query: 2635 HLKMPKVKMPKFSMPGFKGE-GPDGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKLKGP 2693 + P + G +GE GP G LP + V P V GP GP G P Sbjct: 771 AIGPP-------GLQGIRGEPGPPG---LPGS---VGSPGVPGIGPP-GARGPPGGQGPP 816 Query: 2694 KFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDVS-LPKVEGD-----LKGPEVDIKGPK 2747 P IK K L++ GPK GD LP + G L G + P Sbjct: 817 GLSGPP-GIKGEKGFPGFPGLDMPGPK--GDKGAQGLPGITGQSGLPGLPGQQGAPGIPG 873 Query: 2748 VDIDAPDVDVHGPDWHLKMP-KIKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVEC 2806 ++ V G P + P +PG KG+ + P+ D + G K DV Sbjct: 874 FPGSKGEMGVMGTPGQPGSPGPVGAP--GLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGL 931 Query: 2807 PDV----------NIEGPEGKWKSPKFKMPEMHFK-------TPKISMPDIDLNLTG-PK 2848 P +++G +G + K ++ + K TP + D G P Sbjct: 932 PGKPGSMDKVDMGSMKGQKGD-QGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPG 990 Query: 2849 IKGDVDVTGPKVEGDLKGPE-----VDLKGPKVDIDVPDVNVQGPDWHLKMPKMKMPKFS 2903 KGD ++G L GP+ + L G + VP + GP +P K K Sbjct: 991 PKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVP--GIPGPQGSPGLPGDKGAK-- 1046 Query: 2904 MPGFKAEGPEVDVNLP-----KADVDVSG----PKVDVEGPDVNIEGPEGK--LKGPKFK 2952 G K + + +P K D ++G P E + I G G LKG Sbjct: 1047 --GEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGS 1104 Query: 2953 MPEMNIKAPKIPMPDFDLHLKG----PKVKGDVDISLPKVEGDLKGPEVDIRGPQVDIDV 3008 + +P +P D L G P VKG+ LP G GP P D + Sbjct: 1105 VGYPG--SPGLPGEKGDKGLPGLDGIPGVKGEA--GLPGTPGP-TGPAGQKGEPGSD-GI 1158 Query: 3009 PDVGVQGPDWHLKMPKVKMPKFSMPGFKGE-GPDVDVNLP-----------KADLDVSGP 3056 P G G +P P F PG KG+ G +V P K + GP Sbjct: 1159 P--GSAGEKGEPGLPGRGFPGF--PGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGP 1214 Query: 3057 KVDIDVPDV------NIEGPEGKLKGPKFK--MPEMNIKAPKISMPDIDLNLKG----PK 3104 P + EGP+G +GP+ + +P + +P ID +KG P Sbjct: 1215 PGPQGQPGLPGSPGHATEGPKGD-RGPQGQPGLPGLPGPMGPPGLPGID-GVKGDKGNPG 1272 Query: 3105 VKGDMDVSLPKVE-GDMKVPDV----DIKGPKVDINAPDV-DVQGPDWHLKMPKIK--MP 3156 G V PK + G +P + I G K D+ P V QGP + IK Sbjct: 1273 WPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQG 1332 Query: 3157 KISMPGFKG----EGPEVDVNLPKADLDVSGPK 3185 +PG KG GP ++ K + + GP+ Sbjct: 1333 DQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPE 1365 Score = 37.4 bits (85), Expect = 0.44 Identities = 63/233 (27%), Positives = 77/233 (33%), Gaps = 56/233 (24%) Query: 5431 GELKGPGVDVNLKGPRISAPNVDFNLEGPK-VKGSLGATGEIKGPTVGGGLPGIGVQGLE 5489 GE PG+ + P + P EGP+ G G TGE P G G G Sbjct: 49 GERGLPGLQGVIGFPGMQGP------EGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYP 102 Query: 5490 GNLQMPGIKSSGCDVNLPGV----NVKLPTGQISGPEIKG-----------GLKGSEVGF 5534 GN +PGI PG+ K G + P + G G+KG Sbjct: 103 GNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEI 162 Query: 5535 HGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSG 5594 G P + +KG P + P G + G V P + G G Sbjct: 163 LGHVPGMLLKGERGFPGIPGT--------PGPPGLPGLQGPVGPPGFTGPPGPPGPPGPP 214 Query: 5595 GEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQAPGLSVSGPQG 5647 GE KG GL F GPK G KG Q VSGP G Sbjct: 215 GE-KGQM--------------GLSFQGPK---GDKGDQ--------GVSGPPG 241 Score = 35.4 bits (80), Expect = 1.7 Identities = 94/370 (25%), Positives = 130/370 (35%), Gaps = 63/370 (17%) Query: 209 PSGSGAASPTGSAVDIRAGAISASGPELQGAGHSKLQVTMPGIKVGGSGVNVNAKGLDLG 268 P G S T A + S G L G K +PG + GS KG G Sbjct: 991 PKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQ--GSPGLPGDKGAK-G 1047 Query: 269 GRGGVQVPAVDISSSLGGRAVEVQGPSLESGDHGKIKFPTMKVPKFGVSTGREGQTPKAG 328 +G P + I G E GD G FP S G +G+ K Sbjct: 1048 EKGQAGPPGIGIPGLRG-----------EKGDQGIAGFPG--------SPGEKGE--KGS 1086 Query: 329 LRVSAPEVSVGHKGGKPGLTIQAPQLEVSVP-SANIEGLEGKLKGPQITG-PSLEGDLGL 386 + + S G KG PG V P S + G +G P + G P ++G+ GL Sbjct: 1087 IGIPGMPGSPGLKGS-PG--------SVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGL 1137 Query: 387 KGAK-PQGHIGVDASAPQIGGSITGPSVEVQAPDIDVQG----PGSKLNVPKMKVPKF-- 439 G P G G G I G + E P + +G PG+K + F Sbjct: 1138 PGTPGPTGPAGQKGEPGSDG--IPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPG 1195 Query: 440 -----SVSGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLEGKMKGTKVKTPEMI 494 + G+KGE+ + P G+ +PG G + G +G+ + P Sbjct: 1196 LAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGP 1255 Query: 495 IQKPKISMQDVDL-------SLGSPKLKGDIKVSAPGVQG-DVKGPQVALKGSRVDIETP 546 P I D + G P KGD PG QG G + GS+ D+ P Sbjct: 1256 PGLPGIDGVKGDKGNPGWPGAPGVPGPKGD-----PGFQGMPGIGGSPGITGSKGDMGPP 1310 Query: 547 NLEGTLTGPR 556 + G GP+ Sbjct: 1311 GVPG-FQGPK 1319 >gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] Length = 744 Score = 66.2 bits (160), Expect = 9e-10 Identities = 130/457 (28%), Positives = 158/457 (34%), Gaps = 113/457 (24%) Query: 5209 KGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGDLRG 5268 KG++ +G+ GP QGP +P IG PG G + Q P +GD RG Sbjct: 184 KGEIGPMGIPGP----QGPPGP-----HGLPGIGKPG------GPGLPGQ-PGPKGD-RG 226 Query: 5269 PDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPG 5328 P L GP L+GP D P V GP P + G P V PG Sbjct: 227 PK-GLPGPQ-GLRGPKGDKGFGMPGAPGVKGP--------PGMHG------PPGPVGLPG 270 Query: 5329 LNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVG 5388 + GV G PG P L P G+ G I P V Sbjct: 271 VGKPGVTG----------FPG-----------PQGPLGKPGAPGEPGPQGPIGVPGV--- 306 Query: 5389 APDLSLEASEGSIKLPKMKLP-QFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRI 5447 +G +P + P Q GI PG KG Q L GP + P Sbjct: 307 ---------QGPPGIPGIGKPGQDGI--PGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGF 355 Query: 5448 SAPNVDFNLEG-PKVKGSLGATGEIKGPTVGG-----GLPGI-GVQGLEGNLQMPGIKSS 5500 P D + G P G G G I P +GG GLPGI G G G + PG K Sbjct: 356 PGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGE 415 Query: 5501 GCDVNLPGVNVKLPTGQISGPEIKG-----GLKG--SEVGFHGAAPDISVKGPAFNMASP 5553 G V G P G P ++G G G G G I KG A P Sbjct: 416 GGIVGPQG-----PPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVP 470 Query: 5554 ESDFGINLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKF 5613 L GPK + G G+ P + G GG GP Sbjct: 471 GLPGVPGLLGPKGEPGIPGDQGLQGPP--------GIPGIGGP-SGP------------- 508 Query: 5614 AGGLHFSGPKVEGGVKG--GQIGLQAPGLS-VSGPQG 5647 G GPK E G+ G G G+ PG++ + GP G Sbjct: 509 IGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPG 545 Score = 52.0 bits (123), Expect = 2e-05 Identities = 173/649 (26%), Positives = 232/649 (35%), Gaps = 147/649 (22%) Query: 2474 SVPEVEGKLEVPDMNIRGPKVDVNAPDVQAPDWHLKMPKMKMP---------------KF 2518 +VP+ +GK E+P ++RG + P + P +P +P K Sbjct: 103 AVPK-KGK-EIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKP 160 Query: 2519 SMPGFKAEGPEVDVNLPKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPK 2578 MPG G + +P A +I G K +I GP + I GP+G GP P Sbjct: 161 GMPGMP--GKPGAMGMPGAKGEI-GQKGEI-GP-MGIPGPQGP-PGPH--------GLPG 206 Query: 2579 ISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKM 2638 I P GP + G + L GP+ ++GPK D G+ G Sbjct: 207 IGKPG------GPGLPGQPGPKGDRGPKGLPGPQ-GLRGPKGD---KGFGMPGA------ 250 Query: 2639 PKVKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPKVD-IEGPDVNIEGPEGKLKGPKFKM 2697 P VK P PG GP G V LP V P V GP +GP GK P Sbjct: 251 PGVKGP----PGM--HGPPGPVGLP----GVGKPGVTGFPGP----QGPLGKPGAPGEPG 296 Query: 2698 PEMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDV 2757 P+ I P + P P + G + P +G P G K + P + Sbjct: 297 PQGPIGVPGVQGP--------PGIPG---IGKPGQDGIPGQP--GFPGGKGEQGLPGLP- 342 Query: 2758 HGPDWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGPEGK 2817 GP +P I PGF G D + + G K + P + GP G+ Sbjct: 343 -GPPG--------LPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIG--GPPGE 391 Query: 2818 WKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPEVDLKGPKVD 2877 P P GP G + GPK EG + GP+ GPK Sbjct: 392 PGLPGIPGP------------------MGPP--GAIGFPGPKGEGGIVGPQ-GPPGPK-- 428 Query: 2878 IDVPDVNVQG----PDWHLKMPKMKMPKFSMP-GFKAEGPEVDVNLPKADVDVSGPKVDV 2932 + +QG P + ++ M P G K E + V + GPK + Sbjct: 429 ---GEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEP 485 Query: 2933 EGP-DVNIEGPEGKLKGPKFKMPEMNIKAPKIPMPDFDLHLKGPKVKGDVDISLPKVEGD 2991 P D ++GP G P P I P IP P + L GP G I P V G Sbjct: 486 GIPGDQGLQGPPGI---PGIGGPSGPIGPPGIPGPKGEPGLPGP--PGFPGIGKPGVAG- 539 Query: 2992 LKGP--EVDIRGPQVDIDVPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKA 3049 L GP + GPQ +P G GP P V P P +GE LP Sbjct: 540 LHGPPGKPGALGPQGQPGLP--GPPGPPGPPGPPAVMPP---TPPPQGE------YLPDM 588 Query: 3050 DLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMP----EMNIKAPKISMP 3094 L + G K P +GK GP ++MP E+ P + P Sbjct: 589 GLGIDGVK-----PPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAP 632 Score = 45.1 bits (105), Expect = 0.002 Identities = 83/290 (28%), Positives = 102/290 (35%), Gaps = 43/290 (14%) Query: 5383 PKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLH-VNAK-GPQVSGELKGPGVDV 5440 PK P SL +G P + P PG + + K GPQ + PG+ Sbjct: 105 PKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMP- 163 Query: 5441 NLKGPRISAPNVDFNLEGPKVKGSLGATGEI--------KGPTVGGGLPGIGVQGLEGNL 5492 P + P KG +G GEI +GP GLPGIG G G Sbjct: 164 -------GMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLP 216 Query: 5493 QMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMAS 5552 PG K LPG P G + GP+ G KG G GA VKGP M Sbjct: 217 GQPGPKGDRGPKGLPG-----PQG-LRGPK---GDKG--FGMPGAP---GVKGPP-GMHG 261 Query: 5553 PESDFGINLKG-PKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDTS 5611 P G+ G P + G G + P G G G P + Sbjct: 262 PPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQD 321 Query: 5612 KFAGGLHFSGPKVEGGVKG-----GQIGLQAPGLSVSGPQGHLESGSGKV 5656 G F G K E G+ G G G+ PG GP+G + G G V Sbjct: 322 GIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGF--PGPKG--DRGMGGV 367 Score = 42.0 bits (97), Expect = 0.018 Identities = 135/529 (25%), Positives = 194/529 (36%), Gaps = 83/529 (15%) Query: 319 GREGQTPKAG-LRVSAPEVSVGHKGGKPGLTIQAPQLEVSVPSAN-IEGLEGKLKGPQIT 376 G G K G + + + +G KG + I PQ P + + G+ GK GP + Sbjct: 161 GMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQ---GPPGPHGLPGI-GKPGGPGLP 216 Query: 377 G-PSLEGDLGLKGAK-PQGHIGVDAS-------APQIGG--SITGPSVEVQAPDIDVQG- 424 G P +GD G KG PQG G AP + G + GP V P + G Sbjct: 217 GQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGV 276 Query: 425 ---PGSKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLEG 481 PG + + K GA GE P G + VPGV G +P I G +G Sbjct: 277 TGFPGPQGPLGK--------PGAPGEPG------PQGPIGVPGVQGPPGIPGIGKPGQDG 322 Query: 482 KMKGTKVKTPEMIIQKPKISMQDVDLSLGSPKLKGDIKVSAPGVQGD--VKGPQVALKGS 539 + G P K + + + G P L G K PG +GD + G AL G Sbjct: 323 -IPG----QPGFPGGKGEQGLPGLP---GPPGLPGIGKPGFPGPKGDRGMGGVPGAL-GP 373 Query: 540 RVDIETPNLEGTLTGPRLGSPSGKTGTCRISMSEVDLNVAAPKVKGGVDVTLPRVEGKVK 599 R + +G + P +G P G+ G + + + P G + P+ EG + Sbjct: 374 RGE------KGPIGAPGIGGPPGEPG-----LPGIPGPMGPP---GAIGFPGPKGEGGIV 419 Query: 600 VPEVDVRGPKVDVSAPDVEAH--GPEWNLKMPKMKMPTFSTP-GAKGEGPDVHMTLPKGD 656 P+ GP P ++ P + ++ M P G KGE + G Sbjct: 420 GPQ----GPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGV 475 Query: 657 ISISGPKVNVEAPDVNLEGLGGKLKGPDVKLPDMSVKTPKISMPDVDLHVKGTKVKGEYD 716 + GPK P +GL G P + P + P I P + + G G Sbjct: 476 PGLLGPKGEPGIP--GDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGP--PGFPG 531 Query: 717 VTVPKLEGELKGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSVPGFKAEGPEVDVNLPKA 776 + P + G L GP A GP +P P PG A P + Sbjct: 532 IGKPGVAG-LHGPPGKPGA-----LGPQGQPGLPGPPGPP-GPPGPPAVMPPTPPPQGEY 584 Query: 777 DVDISGPKIDVTAPDVSIEEPEGKLKGPKFKMP----EMNIKVPKISMP 821 D+ G ID P + +GK GP ++MP E+ P + P Sbjct: 585 LPDM-GLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAP 632 Score = 40.4 bits (93), Expect = 0.053 Identities = 84/314 (26%), Positives = 109/314 (34%), Gaps = 50/314 (15%) Query: 4645 GPDWHLKMPKVKMP-------KFSMPGFKGEGPDVDVNLPKADIDVSGPKVDVDVPDVNI 4697 GP + + K MP MPG KGE P GP +P + Sbjct: 150 GPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGK 209 Query: 4698 EGPDAK--LKGPKFKMPEMSIKAPKISMPDIDLNLKGPKVKGDVDVTLPKVEGDLKGPEA 4755 G GPK + P+ L+GPK GD +P G +KGP Sbjct: 210 PGGPGLPGQPGPKGDRGPKGLPGPQ--------GLRGPK--GDKGFGMPGAPG-VKGPPG 258 Query: 4756 DIKGPKVDINTPDVDVHGPDWHLKMPKVKMPKFSMPGFKGE-GPDVDVSLPKADIDVSGP 4814 + GP + P V G P + P PG GE GP + +P V GP Sbjct: 259 -MHGPPGPVGLPGVGKPGVTG---FPGPQGP-LGKPGAPGEPGPQGPIGVP----GVQGP 309 Query: 4815 KVDVDIPDVNIEGPDAKLKGPKFKMPEINIKAPKISIPDVDLDLKGPKVKGDFDVSVPKV 4874 IP + G D P F + P + P + P G PK Sbjct: 310 P---GIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPG------PKG 360 Query: 4875 EGTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLHLKAP-KIGFS 4933 + + G L GPR G + P + P E P + P + P IGF Sbjct: 361 DRGMGGVPGAL-GPR----GEKGPIGAPGIGGPPGEPGLPGIPGP-----MGPPGAIGFP 410 Query: 4934 GPKLEGGEVDLKGP 4947 GPK EGG V +GP Sbjct: 411 GPKGEGGIVGPQGP 424 Score = 40.4 bits (93), Expect = 0.053 Identities = 105/367 (28%), Positives = 133/367 (36%), Gaps = 59/367 (16%) Query: 5159 LKGPKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPSVGLE 5218 L+GPK G P + P + P V P V GP+ G + G Sbjct: 236 LRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVT-GFPGPQ--GPLGKPGAP 292 Query: 5219 GPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEG-GGAEVHAQLPSLEGDLRGPDVKLEGPD 5277 G GP+ I P P GIPG+ G G P +G+ P L GP Sbjct: 293 GEP----GPQGPIGVPGVQGPP-GIPGIGKPGQDGIPGQPGFPGGKGEQGLPG--LPGP- 344 Query: 5278 VSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGLN------- 5330 PG LP + P GP D + G + G L + APG+ Sbjct: 345 -----PG--LPGIG--KPGFPGPKGDRGMGG--VPGALGPRGEKGPIGAPGIGGPPGEPG 393 Query: 5331 LSGVGGKMQVGGDGVKVPGIDATTKLNVG--APDVTLRGPSLQGDLAVSGDIKCPKVSVG 5388 L G+ G M G + PG + VG P P LQG G + VG Sbjct: 394 LPGIPGPMGPPG-AIGFPGPKGEGGI-VGPQGPPGPKGEPGLQGFPGKPGFLG----EVG 447 Query: 5389 APDLSLEASEGSIKLPKMKLPQFGI-STPGSDLHVNAKG-PQVSGE--LKGPGVDVNLKG 5444 P + G I PK + Q G+ PG + KG P + G+ L+GP + G Sbjct: 448 PP--GMRGLPGPIG-PKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGG 504 Query: 5445 PRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGIG---VQGLEGNLQMPGIKSSG 5501 P S P + GPK G G + GP G PGIG V GL G PG Sbjct: 505 P--SGPIGPPGIPGPK-----GEPG-LPGPP---GFPGIGKPGVAGLHGPPGKPGALGPQ 553 Query: 5502 CDVNLPG 5508 LPG Sbjct: 554 GQPGLPG 560 >gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] Length = 744 Score = 66.2 bits (160), Expect = 9e-10 Identities = 130/457 (28%), Positives = 158/457 (34%), Gaps = 113/457 (24%) Query: 5209 KGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGDLRG 5268 KG++ +G+ GP QGP +P IG PG G + Q P +GD RG Sbjct: 184 KGEIGPMGIPGP----QGPPGP-----HGLPGIGKPG------GPGLPGQ-PGPKGD-RG 226 Query: 5269 PDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPG 5328 P L GP L+GP D P V GP P + G P V PG Sbjct: 227 PK-GLPGPQ-GLRGPKGDKGFGMPGAPGVKGP--------PGMHG------PPGPVGLPG 270 Query: 5329 LNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVG 5388 + GV G PG P L P G+ G I P V Sbjct: 271 VGKPGVTG----------FPG-----------PQGPLGKPGAPGEPGPQGPIGVPGV--- 306 Query: 5389 APDLSLEASEGSIKLPKMKLP-QFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRI 5447 +G +P + P Q GI PG KG Q L GP + P Sbjct: 307 ---------QGPPGIPGIGKPGQDGI--PGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGF 355 Query: 5448 SAPNVDFNLEG-PKVKGSLGATGEIKGPTVGG-----GLPGI-GVQGLEGNLQMPGIKSS 5500 P D + G P G G G I P +GG GLPGI G G G + PG K Sbjct: 356 PGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGE 415 Query: 5501 GCDVNLPGVNVKLPTGQISGPEIKG-----GLKG--SEVGFHGAAPDISVKGPAFNMASP 5553 G V G P G P ++G G G G G I KG A P Sbjct: 416 GGIVGPQG-----PPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVP 470 Query: 5554 ESDFGINLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKF 5613 L GPK + G G+ P + G GG GP Sbjct: 471 GLPGVPGLLGPKGEPGIPGDQGLQGPP--------GIPGIGGP-SGP------------- 508 Query: 5614 AGGLHFSGPKVEGGVKG--GQIGLQAPGLS-VSGPQG 5647 G GPK E G+ G G G+ PG++ + GP G Sbjct: 509 IGPPGIPGPKGEPGLPGPPGFPGIGKPGVAGLHGPPG 545 Score = 52.0 bits (123), Expect = 2e-05 Identities = 173/649 (26%), Positives = 232/649 (35%), Gaps = 147/649 (22%) Query: 2474 SVPEVEGKLEVPDMNIRGPKVDVNAPDVQAPDWHLKMPKMKMP---------------KF 2518 +VP+ +GK E+P ++RG + P + P +P +P K Sbjct: 103 AVPK-KGK-EIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKP 160 Query: 2519 SMPGFKAEGPEVDVNLPKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPK 2578 MPG G + +P A +I G K +I GP + I GP+G GP P Sbjct: 161 GMPGMP--GKPGAMGMPGAKGEI-GQKGEI-GP-MGIPGPQGP-PGPH--------GLPG 206 Query: 2579 ISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKM 2638 I P GP + G + L GP+ ++GPK D G+ G Sbjct: 207 IGKPG------GPGLPGQPGPKGDRGPKGLPGPQ-GLRGPKGD---KGFGMPGA------ 250 Query: 2639 PKVKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPKVD-IEGPDVNIEGPEGKLKGPKFKM 2697 P VK P PG GP G V LP V P V GP +GP GK P Sbjct: 251 PGVKGP----PGM--HGPPGPVGLP----GVGKPGVTGFPGP----QGPLGKPGAPGEPG 296 Query: 2698 PEMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDV 2757 P+ I P + P P + G + P +G P G K + P + Sbjct: 297 PQGPIGVPGVQGP--------PGIPG---IGKPGQDGIPGQP--GFPGGKGEQGLPGLP- 342 Query: 2758 HGPDWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGPEGK 2817 GP +P I PGF G D + + G K + P + GP G+ Sbjct: 343 -GPPG--------LPGIGKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIG--GPPGE 391 Query: 2818 WKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPEVDLKGPKVD 2877 P P GP G + GPK EG + GP+ GPK Sbjct: 392 PGLPGIPGP------------------MGPP--GAIGFPGPKGEGGIVGPQ-GPPGPK-- 428 Query: 2878 IDVPDVNVQG----PDWHLKMPKMKMPKFSMP-GFKAEGPEVDVNLPKADVDVSGPKVDV 2932 + +QG P + ++ M P G K E + V + GPK + Sbjct: 429 ---GEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGVPGLLGPKGEP 485 Query: 2933 EGP-DVNIEGPEGKLKGPKFKMPEMNIKAPKIPMPDFDLHLKGPKVKGDVDISLPKVEGD 2991 P D ++GP G P P I P IP P + L GP G I P V G Sbjct: 486 GIPGDQGLQGPPGI---PGIGGPSGPIGPPGIPGPKGEPGLPGP--PGFPGIGKPGVAG- 539 Query: 2992 LKGP--EVDIRGPQVDIDVPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKA 3049 L GP + GPQ +P G GP P V P P +GE LP Sbjct: 540 LHGPPGKPGALGPQGQPGLP--GPPGPPGPPGPPAVMPP---TPPPQGE------YLPDM 588 Query: 3050 DLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMP----EMNIKAPKISMP 3094 L + G K P +GK GP ++MP E+ P + P Sbjct: 589 GLGIDGVK-----PPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAP 632 Score = 45.1 bits (105), Expect = 0.002 Identities = 83/290 (28%), Positives = 102/290 (35%), Gaps = 43/290 (14%) Query: 5383 PKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLH-VNAK-GPQVSGELKGPGVDV 5440 PK P SL +G P + P PG + + K GPQ + PG+ Sbjct: 105 PKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMP- 163 Query: 5441 NLKGPRISAPNVDFNLEGPKVKGSLGATGEI--------KGPTVGGGLPGIGVQGLEGNL 5492 P + P KG +G GEI +GP GLPGIG G G Sbjct: 164 -------GMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLP 216 Query: 5493 QMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMAS 5552 PG K LPG P G + GP+ G KG G GA VKGP M Sbjct: 217 GQPGPKGDRGPKGLPG-----PQG-LRGPK---GDKG--FGMPGAP---GVKGPP-GMHG 261 Query: 5553 PESDFGINLKG-PKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDTS 5611 P G+ G P + G G + P G G G P + Sbjct: 262 PPGPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQD 321 Query: 5612 KFAGGLHFSGPKVEGGVKG-----GQIGLQAPGLSVSGPQGHLESGSGKV 5656 G F G K E G+ G G G+ PG GP+G + G G V Sbjct: 322 GIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGF--PGPKG--DRGMGGV 367 Score = 42.0 bits (97), Expect = 0.018 Identities = 135/529 (25%), Positives = 194/529 (36%), Gaps = 83/529 (15%) Query: 319 GREGQTPKAG-LRVSAPEVSVGHKGGKPGLTIQAPQLEVSVPSAN-IEGLEGKLKGPQIT 376 G G K G + + + +G KG + I PQ P + + G+ GK GP + Sbjct: 161 GMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQ---GPPGPHGLPGI-GKPGGPGLP 216 Query: 377 G-PSLEGDLGLKGAK-PQGHIGVDAS-------APQIGG--SITGPSVEVQAPDIDVQG- 424 G P +GD G KG PQG G AP + G + GP V P + G Sbjct: 217 GQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGV 276 Query: 425 ---PGSKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLEG 481 PG + + K GA GE P G + VPGV G +P I G +G Sbjct: 277 TGFPGPQGPLGK--------PGAPGEPG------PQGPIGVPGVQGPPGIPGIGKPGQDG 322 Query: 482 KMKGTKVKTPEMIIQKPKISMQDVDLSLGSPKLKGDIKVSAPGVQGD--VKGPQVALKGS 539 + G P K + + + G P L G K PG +GD + G AL G Sbjct: 323 -IPG----QPGFPGGKGEQGLPGLP---GPPGLPGIGKPGFPGPKGDRGMGGVPGAL-GP 373 Query: 540 RVDIETPNLEGTLTGPRLGSPSGKTGTCRISMSEVDLNVAAPKVKGGVDVTLPRVEGKVK 599 R + +G + P +G P G+ G + + + P G + P+ EG + Sbjct: 374 RGE------KGPIGAPGIGGPPGEPG-----LPGIPGPMGPP---GAIGFPGPKGEGGIV 419 Query: 600 VPEVDVRGPKVDVSAPDVEAH--GPEWNLKMPKMKMPTFSTP-GAKGEGPDVHMTLPKGD 656 P+ GP P ++ P + ++ M P G KGE + G Sbjct: 420 GPQ----GPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPKGEAGQKGVPGLPGV 475 Query: 657 ISISGPKVNVEAPDVNLEGLGGKLKGPDVKLPDMSVKTPKISMPDVDLHVKGTKVKGEYD 716 + GPK P +GL G P + P + P I P + + G G Sbjct: 476 PGLLGPKGEPGIP--GDQGLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGP--PGFPG 531 Query: 717 VTVPKLEGELKGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSVPGFKAEGPEVDVNLPKA 776 + P + G L GP A GP +P P PG A P + Sbjct: 532 IGKPGVAG-LHGPPGKPGA-----LGPQGQPGLPGPPGPP-GPPGPPAVMPPTPPPQGEY 584 Query: 777 DVDISGPKIDVTAPDVSIEEPEGKLKGPKFKMP----EMNIKVPKISMP 821 D+ G ID P + +GK GP ++MP E+ P + P Sbjct: 585 LPDM-GLGIDGVKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAP 632 Score = 40.4 bits (93), Expect = 0.053 Identities = 84/314 (26%), Positives = 109/314 (34%), Gaps = 50/314 (15%) Query: 4645 GPDWHLKMPKVKMP-------KFSMPGFKGEGPDVDVNLPKADIDVSGPKVDVDVPDVNI 4697 GP + + K MP MPG KGE P GP +P + Sbjct: 150 GPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGK 209 Query: 4698 EGPDAK--LKGPKFKMPEMSIKAPKISMPDIDLNLKGPKVKGDVDVTLPKVEGDLKGPEA 4755 G GPK + P+ L+GPK GD +P G +KGP Sbjct: 210 PGGPGLPGQPGPKGDRGPKGLPGPQ--------GLRGPK--GDKGFGMPGAPG-VKGPPG 258 Query: 4756 DIKGPKVDINTPDVDVHGPDWHLKMPKVKMPKFSMPGFKGE-GPDVDVSLPKADIDVSGP 4814 + GP + P V G P + P PG GE GP + +P V GP Sbjct: 259 -MHGPPGPVGLPGVGKPGVTG---FPGPQGP-LGKPGAPGEPGPQGPIGVP----GVQGP 309 Query: 4815 KVDVDIPDVNIEGPDAKLKGPKFKMPEINIKAPKISIPDVDLDLKGPKVKGDFDVSVPKV 4874 IP + G D P F + P + P + P G PK Sbjct: 310 P---GIPGIGKPGQDGIPGQPGFPGGKGEQGLPGLPGPPGLPGIGKPGFPG------PKG 360 Query: 4875 EGTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLHLKAP-KIGFS 4933 + + G L GPR G + P + P E P + P + P IGF Sbjct: 361 DRGMGGVPGAL-GPR----GEKGPIGAPGIGGPPGEPGLPGIPGP-----MGPPGAIGFP 410 Query: 4934 GPKLEGGEVDLKGP 4947 GPK EGG V +GP Sbjct: 411 GPKGEGGIVGPQGP 424 Score = 40.4 bits (93), Expect = 0.053 Identities = 105/367 (28%), Positives = 133/367 (36%), Gaps = 59/367 (16%) Query: 5159 LKGPKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPSVGLE 5218 L+GPK G P + P + P V P V GP+ G + G Sbjct: 236 LRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVGKPGVT-GFPGPQ--GPLGKPGAP 292 Query: 5219 GPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEG-GGAEVHAQLPSLEGDLRGPDVKLEGPD 5277 G GP+ I P P GIPG+ G G P +G+ P L GP Sbjct: 293 GEP----GPQGPIGVPGVQGPP-GIPGIGKPGQDGIPGQPGFPGGKGEQGLPG--LPGP- 344 Query: 5278 VSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGLN------- 5330 PG LP + P GP D + G + G L + APG+ Sbjct: 345 -----PG--LPGIG--KPGFPGPKGDRGMGG--VPGALGPRGEKGPIGAPGIGGPPGEPG 393 Query: 5331 LSGVGGKMQVGGDGVKVPGIDATTKLNVG--APDVTLRGPSLQGDLAVSGDIKCPKVSVG 5388 L G+ G M G + PG + VG P P LQG G + VG Sbjct: 394 LPGIPGPMGPPG-AIGFPGPKGEGGI-VGPQGPPGPKGEPGLQGFPGKPGFLG----EVG 447 Query: 5389 APDLSLEASEGSIKLPKMKLPQFGI-STPGSDLHVNAKG-PQVSGE--LKGPGVDVNLKG 5444 P + G I PK + Q G+ PG + KG P + G+ L+GP + G Sbjct: 448 PP--GMRGLPGPIG-PKGEAGQKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGG 504 Query: 5445 PRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGIG---VQGLEGNLQMPGIKSSG 5501 P S P + GPK G G + GP G PGIG V GL G PG Sbjct: 505 P--SGPIGPPGIPGPK-----GEPG-LPGPP---GFPGIGKPGVAGLHGPPGKPGALGPQ 553 Query: 5502 CDVNLPG 5508 LPG Sbjct: 554 GQPGLPG 560 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 65.9 bits (159), Expect = 1e-09 Identities = 139/499 (27%), Positives = 188/499 (37%), Gaps = 91/499 (18%) Query: 5205 GPKIKGDVPSVGLEGPD--VDLQGPEAKIKFPKFSMPK--IGIPGVKMEGG-----GAEV 5255 GPK+ D P GL G L+G + + PK G+PG+K + G G + Sbjct: 2091 GPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDG 2150 Query: 5256 HAQLPSLEGDLRGPDVK-----LEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPS 5310 + LP G + GP+ K GP + G G P P ++GP +GPS Sbjct: 2151 NPGLPGERG-MAGPEGKPGLQGPRGPPGPVGGHGDPGPP---GAPGLAGP---AGPQGPS 2203 Query: 5311 -LKGDLDASVPSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPS 5369 LKG+ + P PG L+G G V +PG + L VG P Sbjct: 2204 GLKGEPGETGP------PGRGLTGPTG-------AVGLPGPPGPSGL-VGPQG----SPG 2245 Query: 5370 LQGDLAVSGDIKCP---KVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKG 5426 L G + +G P S D GS LP P+ G+ Sbjct: 2246 LPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGL 2305 Query: 5427 PQVSGELKGPGVDVNLKGPRISAPNV--DFNLEGPK-VKGSLGATGE-----------IK 5472 P GE PG L G + P D L GP+ KG G GE Sbjct: 2306 PGAKGEKGAPG---GLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAP 2362 Query: 5473 GPTVGGGLPGIGV---------QGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQIS--GP 5521 GP G PG+GV G++G+L +PG+ + V PG P G++ GP Sbjct: 2363 GPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTG--PRGEMGQPGP 2420 Query: 5522 EIKGGLKGSEVGFHGAAPDISVKGPAFNMASP--------ESDFGINLKGPK-IKGGADV 5572 + GL G G G + GP ++ P + D G+ L GP+ +G + Sbjct: 2421 SGERGLAGPP-GREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGI 2479 Query: 5573 SGGVSAPDISLGEGHLSVKGSGGE--WKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKG 5630 G P G GS GE KG S+ L D A L GP+ G K Sbjct: 2480 RGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPR---GAK- 2535 Query: 5631 GQIGLQAP-GL-SVSGPQG 5647 G +G + P GL GP+G Sbjct: 2536 GDMGERGPRGLDGDKGPRG 2554 Score = 61.6 bits (148), Expect = 2e-08 Identities = 149/540 (27%), Positives = 201/540 (37%), Gaps = 89/540 (16%) Query: 5153 PKIEGDLKGPKVQANLGAPDINIEGLDAKVKTPSFGISAPQVS--IPDVNVNLKGPKIKG 5210 PK+ D GP + G P + AK + S G P+ +P + + P +G Sbjct: 2092 PKVSVDEPGPGLSGEQGPPGLK----GAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRG 2147 Query: 5211 DVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGDL--RG 5268 + GL G + + GPE K P P+ G PG + G G P L G +G Sbjct: 2148 QDGNPGLPG-ERGMAGPEGK---PGLQGPR-GPPG-PVGGHGDPGPPGAPGLAGPAGPQG 2201 Query: 5269 PD-VKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSM-KVHA 5326 P +K E + G G+ P+ + +P GP L GP L V K A Sbjct: 2202 PSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPS---GLVGPQGSPGLPGQVGETGKPGA 2258 Query: 5327 PGLNLSGVGGKMQVGGDGVKVPGIDATTKLN-----------VGAPDVTLRG-PSLQGDL 5374 PG + G GK G PG+ + L GAP + G P +G+ Sbjct: 2259 PGRD--GASGKDGDRGS----PGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEK 2312 Query: 5375 AVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGI-STPGSDLHVNAKGPQVSGEL 5433 G + V G P + + K + + G PG D A GP+ G Sbjct: 2313 GAPGGLAGDLV--GEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPK--GFK 2368 Query: 5434 KGPGVDVNLKGPRISAPNV--DFNLEG----PKVKGSLGATGE--------------IKG 5473 PGV V P V D L G P V G G TG + G Sbjct: 2369 GDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAG 2428 Query: 5474 PTVGGGLPG-IGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEV 5532 P G+PG +G G G++ PG D PGV + P G+ P I+G E Sbjct: 2429 PPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRG-----ED 2483 Query: 5533 GFHGAAPDISVKGPAFNMA--SPESDFG-INLKGPKIKGGADVSGGVSAPDISLGE-GHL 5588 G G + GP + + D G LKG KG + V G P + G+ G Sbjct: 2484 GRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGD--KGDSAVILGPPGPRGAKGDMGER 2541 Query: 5589 SVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQAPGL-SVSGPQG 5647 +G G+ KGP+ + G G K E G K G GL PGL + GPQG Sbjct: 2542 GPRGLDGD-KGPRGDN----------GDPGDKGSKGEPGDK-GSAGL--PGLRGLLGPQG 2587 Score = 57.0 bits (136), Expect = 5e-07 Identities = 130/490 (26%), Positives = 168/490 (34%), Gaps = 103/490 (21%) Query: 5208 IKGDVPSVGLEGP------DVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPS 5261 +KGD G +GP + GP P K GIPG+ GG A P Sbjct: 2004 LKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPG----KPGIPGLPGRAGGVG-EAGRPG 2058 Query: 5262 LEGDLRGPDVKL--EGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASV 5319 G+ RG + +G D PG P P GP + ++ GP L G+ Sbjct: 2059 ERGE-RGEKGERGEQGRDGPPGLPGTPGP------PGPPGPKVSVDEPGPGLSGEQGP-- 2109 Query: 5320 PSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRG-PSLQGDLAVSG 5378 PGL G K + G +G + P D RG P ++GD G Sbjct: 2110 -------PGLK----GAKGEPGSNGDQGPKGD--------------RGVPGIKGDRGEPG 2144 Query: 5379 DIKCPKVSVGAPDL----SLEASEGSIKLPKMKLPQFGIS------TPGSDLHVNAKGPQ 5428 P+ G P L + EG L + P + PG+ GPQ Sbjct: 2145 ----PRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQ 2200 Query: 5429 VSGELKGPGVDVNLKGPRISAPNVDFNLEGPK-------VKGSLGATGEIKGPTVGGGLP 5481 LKG + G ++ P L GP +GS G G++ G T G P Sbjct: 2201 GPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQV-GETGKPGAP 2259 Query: 5482 GI-GVQGLEGNLQMPGIKSSGCDVNLPG-VNVKLPTGQISGPE--------------IKG 5525 G G G +G+ PG+ S LPG V K G P G Sbjct: 2260 GRDGASGKDGDRGSPGVPGSP---GLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPG 2316 Query: 5526 GLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGE 5585 GL G VG GA D + GP G G D G P G+ Sbjct: 2317 GLAGDLVGEPGAKGDRGLPGPRGEKGE------AGRAGEPGDPGEDGQKGAPGPKGFKGD 2370 Query: 5586 GHLSVKGSGGEWKGPQVSSALNLDTSKFAGGL----HFSGPKVEGGVKG--GQIGLQAP- 5638 + V GS G P V L L A G+ +GP+ E G G G+ GL P Sbjct: 2371 PGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPP 2430 Query: 5639 -GLSVSGPQG 5647 + GP G Sbjct: 2431 GREGIPGPLG 2440 Score = 56.6 bits (135), Expect = 7e-07 Identities = 111/383 (28%), Positives = 142/383 (37%), Gaps = 65/383 (16%) Query: 208 LPSGSGAASPTGSAVDIRAGAISASGPELQGAGHSKLQVTMPGIK-VGGSGVNVNAKGLD 266 LP G A P G + G GP GH PG + G GL Sbjct: 2154 LPGERGMAGPEG-----KPGLQGPRGPPGPVGGHG--DPGPPGAPGLAGPAGPQGPSGLK 2206 Query: 267 LGGRGGVQVPAVDISSSLGGRAVEVQGPSLESGDHGKIKFPTM--KVPKFGV--STGREG 322 G G P ++ G AV + GP SG G P + +V + G + GR+G Sbjct: 2207 -GEPGETGPPGRGLTGPTG--AVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDG 2263 Query: 323 QTPKAGLRVSAPEVS--------VGHKGGKPGLTIQAPQLEVSVPSANIE-GLEGKLKGP 373 + K G R S P V VG KG +PG T Q V +P A E G G L G Sbjct: 2264 ASGKDGDRGS-PGVPGSPGLPGPVGPKG-EPGPTGAPGQAVVGLPGAKGEKGAPGGLAGD 2321 Query: 374 QITGPSLEGDLGLKGAKPQGHIGVDASAPQIGGSITGPSVEVQAPDIDVQGPGSKLNVPK 433 + P +GD GL G P+G G A + G D PG K Sbjct: 2322 LVGEPGAKGDRGLPG--PRGEKGEAGRAGEPGDP---------GEDGQKGAPGPK----- 2365 Query: 434 MKVPKFSVSGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEI--ATG--------GLEGKM 483 G KG+ G+ V G PGV GD+ LP + A G G G+M Sbjct: 2366 ---------GFKGDP-GVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEM 2415 Query: 484 KGTKVKTPEMIIQKPKISMQDVDLSLGSPKLKGDI-KVSAPGVQGDVKGPQVALKGSRVD 542 G + E + P + + LG P G + A G++GD P V L G R + Sbjct: 2416 -GQPGPSGERGLAGPP-GREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGE 2473 Query: 543 IETPNLEGTLTGPRLGSPSGKTG 565 P + G P P G TG Sbjct: 2474 RGEPGIRGEDGRPGQEGPRGLTG 2496 Score = 55.8 bits (133), Expect = 1e-06 Identities = 210/821 (25%), Positives = 279/821 (33%), Gaps = 197/821 (23%) Query: 4813 GPKVDVDIPDVNIEGPDAK--LKGPKFKMPEINIKAPK--ISIPDVDLDLKGPKVKG-DF 4867 GPKV VD P + G LKG K + + PK +P + D P +G D Sbjct: 2091 GPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDG 2150 Query: 4868 DVSVPKVEGTLKGPE--VDLKGPRLDFEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLHL 4925 + +P G + GPE L+GPR GP + G P AP + P Sbjct: 2151 NPGLPGERG-MAGPEGKPGLQGPR----GPPGPVGGHGDPGPP---GAPGLAGP------ 2196 Query: 4926 KAPKIGFSGPKLEGGEVDLKGPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKFGFGAK 4985 A G SG K E GE G + P+ V + P GP G Sbjct: 2197 -AGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPP----GPS-------------GLV 2238 Query: 4986 SPKADIKSPSLDVTVPEAELNLETPEISVGGKGKKSKFKMPKIHMSGPKIKAKKQGFDLN 5045 P+ SP L V E G G+ A + D Sbjct: 2239 GPQG---SPGLPGQVGETG--------KPGAPGRDG---------------ASGKDGDRG 2272 Query: 5046 VPGGEIDASLKAPDVDVNIAGPDAA---LKVDVKSPKTKKTMFGKMYFPDVEFDIKSPKF 5102 PG L P GP A V + K +K G + D+ + P Sbjct: 2273 SPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLA-GDL---VGEPGA 2328 Query: 5103 KAEAPLPSPKLE-GELQAPDLELSLPAIHVEGLDIKAKAPKVKMPDVDISVPKIEGDLKG 5161 K + LP P+ E GE P E A PK D + VP G Sbjct: 2329 KGDRGLPGPRGEKGEAG----RAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGP 2384 Query: 5162 PKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSI----PDVNVNLKGPKIKGDVPS-VG 5216 P V+ +LG P + G V P G + P+ + P L GP + +P +G Sbjct: 2385 PGVKGDLGLP--GLPGAPGVVGFP--GQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLG 2440 Query: 5217 LEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGP 5276 GP + P A P +G+PG + E G E +RG D + Sbjct: 2441 PPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERG-----------EPGIRGEDGR---- 2485 Query: 5277 DVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLSGVGG 5336 PG + P ++GP P +G+ G Sbjct: 2486 ------PGQEGPR------GLTGP--------PGSRGER-------------------GE 2506 Query: 5337 KMQVGGDGVKVPGIDATTKLNVGAP-----DVTLRGP-SLQGDLAVSGDIKCP--KVSVG 5388 K VG G+K D+ L P D+ RGP L GD GD P K S G Sbjct: 2507 KGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKG 2566 Query: 5389 APDLSLEASEGSIKLPKMK---LPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGP 5445 P +GS LP ++ PQ G + G ++G DV GP Sbjct: 2567 EP-----GDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGP 2621 Query: 5446 RISAPNVDFNLEGPK-VKGSLGATGEIKGPTVGGGLPG-IGVQGLEGNLQMPGIKSSGCD 5503 R L+G + VKG+ G GE KG G PG G+ G +G + PG+ Sbjct: 2622 R--------GLKGERGVKGACGLDGE-KGDKGEAGPPGRPGLAGHKGEMGEPGV------ 2666 Query: 5504 VNLPGVNVKLPTGQISGPEIKG--GLKGSEVGFHGAAPDISVKGPAFNMASPESDFGI-N 5560 GQ P +G G KG GF G +G +P GI Sbjct: 2667 -----------PGQSGAPGKEGLIGPKGDR-GFDGQPGPKGDQGEKGERGTP----GIGG 2710 Query: 5561 LKGPKIKGGADVSGGVSAPDISLG-EGHLSVKGSGGEWKGP 5600 GP G D S G P S+G G ++G GE +GP Sbjct: 2711 FPGP---SGNDGSAGPPGPPGSVGPRGPEGLQGQKGE-RGP 2747 Score = 50.1 bits (118), Expect = 7e-05 Identities = 142/506 (28%), Positives = 184/506 (36%), Gaps = 85/506 (16%) Query: 5161 GPKVQAN-LGAPDINIEGLDAKV--KTPSFGISAPQVSIPDVNVN--LKGPK-IKGDVPS 5214 GPK + GAP + GL K G++ V P + L GP+ KG+ Sbjct: 2287 GPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGR 2346 Query: 5215 VGLEG-PDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKL 5273 G G P D Q K K P +G+PG G P ++GDL P L Sbjct: 2347 AGEPGDPGEDGQKGAPGPKGFKGD-PGVGVPGSPGPPGP-------PGVKGDLGLPG--L 2396 Query: 5274 EGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGP----SLKGDLDASVPSMKVHAPGL 5329 G + PG P + P GP + L GP + G L P V PG Sbjct: 2397 PGAPGVVGFPGQTGPRGEMGQP---GPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGA 2453 Query: 5330 NLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGA 5389 + G K G GV +PG P P ++G+ G + P+ G Sbjct: 2454 S----GLKGDKGDPGVGLPG-----------PRGERGEPGIRGEDGRPGQ-EGPRGLTGP 2497 Query: 5390 PDLSLEASE----GSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGP 5445 P E E GS L K I P AKG GE G+D + KGP Sbjct: 2498 PGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPR--GAKGDM--GERGPRGLDGD-KGP 2552 Query: 5446 RISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPG----IGVQGLEGNLQMPGIKSSG 5501 R N D P KGS G G+ KG GLPG +G QG G +PG S Sbjct: 2553 R--GDNGD-----PGDKGSKGEPGD-KG---SAGLPGLRGLLGPQGQPGAAGIPGDPGSP 2601 Query: 5502 CDVNLPGVNVKLPTGQISGPE-IKG--GLKGSEVGFHGAAPDISVKGPAFNMASPESDFG 5558 +PG+ + GP +KG G+KG+ G G D GP Sbjct: 2602 GKDGVPGIRGEKGDVGFMGPRGLKGERGVKGA-CGLDGEKGDKGEAGPPGRPGLAGHKGE 2660 Query: 5559 INLKGPKIKGGADVSGGVSAPDISLG-EGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGL 5617 + G + GA G+ P G +G KG GE KG + + + GG Sbjct: 2661 MGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGE-KGERGTPGI--------GG- 2710 Query: 5618 HFSGPKVEGGVKG-----GQIGLQAP 5638 F GP G G G +G + P Sbjct: 2711 -FPGPSGNDGSAGPPGPPGSVGPRGP 2735 Score = 43.1 bits (100), Expect = 0.008 Identities = 93/331 (28%), Positives = 115/331 (34%), Gaps = 42/331 (12%) Query: 5339 QVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCP--KVSVGAPDLSLEA 5396 + G G + P AT K G P R P G G P K S G P + Sbjct: 1279 RTGAPGPQGPPGSATAKGERGFPGADGR-PGSPGRAGNPGTPGAPGLKGSPGLPGPRGDP 1337 Query: 5397 SEGSIKLPKMKLPQFGISTPGSDLHV-NAKGPQVSGELKGPGVDVNLKGPR----ISAPN 5451 E + PK PG+ V +GP + G PG GPR P Sbjct: 1338 GERGPRGPK--------GEPGAPGQVIGGEGPGLPGRKGDPGPS-GPPGPRGPLGDPGPR 1388 Query: 5452 VDFNLEGPKVKGSLGATGE--IKGPTVGG------GLPGI-GVQGLEGNLQMPGIKSSGC 5502 L G +KG G GE GP GG GLPG+ G G +G + PG K Sbjct: 1389 GPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKG 1448 Query: 5503 DV--NLPGVNVKLPTGQISGPEIKGGLKG--SEVGFHGAAPDISVKGPAFNMASPESDFG 5558 D PG+ + + GP G G + GF G + KG P Sbjct: 1449 DSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKG---ERGPPGPAGS 1505 Query: 5559 INLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLH 5618 L G + GA G P GE KG G P V G + Sbjct: 1506 RGLPGVAGRPGAKGPEGPPGPTGRQGE-----KGEPGRPGDPAVVGPAVAGPKGEKGDVG 1560 Query: 5619 FSGPKVEGGVKG--GQIGLQAPGLSVSGPQG 5647 +GP+ GV+G G GL PG GP+G Sbjct: 1561 PAGPRGATGVQGERGPPGLVLPG--DPGPKG 1589 Score = 40.4 bits (93), Expect = 0.053 Identities = 138/563 (24%), Positives = 195/563 (34%), Gaps = 97/563 (17%) Query: 292 QGPSLESGDHGKIKFPTMKVP-KFGVSTGREGQTPKAGLRVSAPEVSVGHKG--GKPGLT 348 +GP +SG+ G P + P F G +G G + P +++G +G G GL Sbjct: 1978 RGPKGDSGEQGP---PGKEGPIGFPGERGLKGDRGDPGPQ-GPPGLALGERGPPGPSGLA 2033 Query: 349 IQAPQLEVSVPSANIEGLEGKLKGPQITG-PSLEGDLGLKGAKPQGHIGVDASAPQIGGS 407 + + I GL G+ G G P G+ G KG + G G D P + G+ Sbjct: 2034 GEPGK-------PGIPGLPGRAGGVGEAGRPGERGERGEKGER--GEQGRDGP-PGLPGT 2083 Query: 408 ITGPSVEVQAPDIDVQGPG--SKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVPGV 465 P +D GPG + P +K GAKGE P G+ VPG+ Sbjct: 2084 PGPPGPPGPKVSVDEPGPGLSGEQGPPGLK-------GAKGEPGSNGDQGPKGDRGVPGI 2136 Query: 466 SGDVSLP----EIATGGLEGKMKGTKVKTPEMIIQKPK-----ISMQDVDLSLGSPKLKG 516 GD P + GL G+ +G + +Q P+ + G+P L G Sbjct: 2137 KGDRGEPGPRGQDGNPGLPGE-RGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAG 2195 Query: 517 DIKVSAP----GVQGDVKGPQVALKGSRVDIETPNLEGT--LTGPRLGSPS-----GKTG 565 P G G+ P L G + P G L GP+ GSP G+TG Sbjct: 2196 PAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQ-GSPGLPGQVGETG 2254 Query: 566 ----TCRISMSEVDLNVAAPKVKGGVDVT-------LPRVEGKVKVPEVDVRGPKVDVSA 614 R S D + +P V G + P G V + G K + A Sbjct: 2255 KPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGA 2314 Query: 615 PDVEAHGPEWNLKMPKMKMPTFSTPGAKGEGPDVHMTLPKGD------ISISGPKVNVEA 668 P G +L PG +GE + GD GPK Sbjct: 2315 PG----GLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGD 2370 Query: 669 PDVNLEGLGGKLKGPDVK----LPDMSVKTPKISMPDVDLHVKGTKVKGEYDVTVPKLEG 724 P V + G G P VK LP + + P T +GE P E Sbjct: 2371 PGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPG------QTGPRGEMGQPGPSGER 2424 Query: 725 ELKGP--KVDIDAPDVDVHGPDWHLKMPKMKMPKFSVPGFKAEGPEVDVNLPKADVDISG 782 L GP + I P + GP + P G K + + V LP G Sbjct: 2425 GLAGPPGREGIPGP-LGPPGPPGSVGPP-------GASGLKGDKGDPGVGLP-------G 2469 Query: 783 PKIDVTAPDVSIEEPEGKLKGPK 805 P+ + P + E+ +GP+ Sbjct: 2470 PRGERGEPGIRGEDGRPGQEGPR 2492 Score = 40.0 bits (92), Expect = 0.069 Identities = 54/176 (30%), Positives = 72/176 (40%), Gaps = 26/176 (14%) Query: 5426 GPQVSGELKGPGVDVNLKGPRISAPNVD--FNLEG-PKVKGSLGATGEI--KGPTVGGGL 5480 GPQ ++GP + +GP P +D L+G P G G G G GL Sbjct: 1755 GPQGDPGVRGPAGEKGDRGP----PGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGL 1810 Query: 5481 PGI-GVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAP 5539 PG+ G QGL G PG+ + PG+N K G+ P + G KG E G GA+ Sbjct: 1811 PGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGK--NGEPGDPG-EDGRKG-EKGDSGASG 1866 Query: 5540 DISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGG 5595 GP +P + GP +G + G V P G+G V G G Sbjct: 1867 REGRDGPKGERGAP------GILGP--QGPPGLPGPVGPP----GQGFPGVPGGTG 1910 Score = 39.7 bits (91), Expect = 0.090 Identities = 126/488 (25%), Positives = 162/488 (33%), Gaps = 96/488 (19%) Query: 5203 LKGPKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMP-------KIGIPGVKMEGGGAEV 5255 L G +KGD G GP +G A + +P +G PG K E G +E Sbjct: 1393 LPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSED 1452 Query: 5256 HAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGP----SL 5311 A P L G P +GP +GP P GP D GP Sbjct: 1453 GA--PGLPGQPGSPGE--QGP----RGP-----------PGAIGPKGDRGFPGPLGEAGE 1493 Query: 5312 KGDLDASVPSMKVHAPGLNLSGVGGKMQVGG-DGVKVPGIDATTKLNVGAP-DVTLRGPS 5369 KG+ P A L GV G+ G +G P K G P D + GP+ Sbjct: 1494 KGERGPPGP-----AGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPA 1548 Query: 5370 LQGDLAVSGDI--KCPKVSVGA------PDLSLEAS---------EGSIKLPKMKLPQFG 5412 + G GD+ P+ + G P L L G I L P Sbjct: 1549 VAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGD 1608 Query: 5413 ISTPGSDLHVNAKGPQVSGELKGPGVDVNLKG-------PRISAPNVDFNLEG-PKVKGS 5464 PG GP +G +V KG P + + L G P V+G Sbjct: 1609 SGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGP 1668 Query: 5465 LGATGEIKGPTVGG--GLPG-IGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGP 5521 +G G+ P G G PG G +G G PG D PG K G G Sbjct: 1669 VGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTG-PGAREKGEPGD-RGQ 1726 Query: 5522 EIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDI 5581 E G KG + G GA + ++G P+ D P ++G A G P + Sbjct: 1727 EGPRGPKG-DPGLPGAPGERGIEG-FRGPPGPQGD-------PGVRGPAGEKGDRGPPGL 1777 Query: 5582 SLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKG--GQIGLQAPG 5639 G L K GP G +G G+ G G+ GL P Sbjct: 1778 D-GRSGLDGKPGAAGPSGPN-------------GAAGKAGDPGRDGLPGLRGEQGLPGP- 1822 Query: 5640 LSVSGPQG 5647 SGP G Sbjct: 1823 ---SGPPG 1827 Score = 38.9 bits (89), Expect = 0.15 Identities = 125/506 (24%), Positives = 166/506 (32%), Gaps = 93/506 (18%) Query: 208 LPSGSGAASPTGS-------------AVDIRAGAISASG-PELQGAGHSKLQVTMPGIKV 253 LP +GA P G D R G+ +G P GA K +PG + Sbjct: 1276 LPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRG 1335 Query: 254 G-------GSGVNVNAKGLDLGGRGGVQVPAVDISSSLGGRAVEVQGPSLESGDHGKIKF 306 G A G +GG G L GR + GPS G G + Sbjct: 1336 DPGERGPRGPKGEPGAPGQVIGGEG----------PGLPGRKGD-PGPSGPPGPRGPLGD 1384 Query: 307 PTMKVPKFGVSTGREGQTPKAGLRVSAPEVSVGHKGGKPGLT----IQAPQLEVSVPSAN 362 P + P T +G G R G G+PGL PQ V P Sbjct: 1385 PGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKK 1444 Query: 363 IEGLEGKLKGPQITG-PSLEGDLGLKGAKPQGHIGVDASAPQIGGSITGPSVEV-QAPDI 420 E + + P + G P G+ G +G P G IG P+ GP E + + Sbjct: 1445 GEKGDSEDGAPGLPGQPGSPGEQGPRG--PPGAIG-----PKGDRGFPGPLGEAGEKGER 1497 Query: 421 DVQGPGSKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLE 480 GP +P + GAKG E T GE PG GD ++ A G + Sbjct: 1498 GPPGPAGSRGLPGVA----GRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPK 1553 Query: 481 GKMKGTKVKTPEMII------QKPKISMQDVDLSLGSPKLKGDIKVSA----------PG 524 G+ P P + + G P +G I ++ PG Sbjct: 1554 GEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPG 1613 Query: 525 VQGDVKGP----QVALKGSRVDIETPNLEGTLTGPRLGSPSGKTGTCRISMSEVDLNVAA 580 +GD P V +G ++ EG P L +G+ G A Sbjct: 1614 EKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGL-----------RGA 1662 Query: 581 PKVKGGV----DVTLPRVEGKVKVPEVDVRGPKVDVSAPDVEAHGPEWNLKMPKMKMPTF 636 P V+G V D P +G+ P GPK D P GP L Sbjct: 1663 PGVRGPVGEKGDQGDPGEDGRNGSP--GSSGPKGDRGEPG--PPGPPGRLVDTGPGAREK 1718 Query: 637 STPGAKG-EGPDVHMTLPKGDISISG 661 PG +G EGP PKGD + G Sbjct: 1719 GEPGDRGQEGP----RGPKGDPGLPG 1740 Score = 38.1 bits (87), Expect = 0.26 Identities = 162/664 (24%), Positives = 216/664 (32%), Gaps = 160/664 (24%) Query: 5205 GPKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEG 5264 G + KG+ G EGP +GP+ P G PG + G E P +G Sbjct: 1714 GAREKGEPGDRGQEGP----RGPKGDPGLP-------GAPGER----GIEGFRGPPGPQG 1758 Query: 5265 D--LRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKG----------PSLK 5312 D +RGP G PG+D S P +GP G P L+ Sbjct: 1759 DPGVRGP----AGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLR 1814 Query: 5313 GDLDASVPSMKVHAPGL----NLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGP 5368 G+ PS PG G+ GK GD PG D Sbjct: 1815 GEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGD----PGEDGRK-------------- 1856 Query: 5369 SLQGDLAVSG--DIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKG 5426 +GD SG PK GAP + +G LP P G PG KG Sbjct: 1857 GEKGDSGASGREGRDGPKGERGAPGIL--GPQGPPGLPGPVGPP-GQGFPGVPGGTGPKG 1913 Query: 5427 PQVSGELKG----PGVDVNLKGPRISAPNVDFNLEGPKVKGS-LGATGEIKGPTVGGGLP 5481 + KG PG + L+G S PNVD LE +K S L E + G LP Sbjct: 1914 DRGETGSKGEQGLPG-ERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLP 1972 Query: 5482 -------------GIGVQGLEGNLQMPGIKSSGCDVNLPG--------VNVKLPTGQ--I 5518 G G EG + PG + D PG + + P G + Sbjct: 1973 VPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGL 2032 Query: 5519 SGPEIKGGLKG--------SEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGA 5570 +G K G+ G E G G + KG GP G Sbjct: 2033 AGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGP 2092 Query: 5571 DVSGGVSAPDISLGEGHLSVKGSGGE--------WKGPQVSSALNLDTSK---------- 5612 VS P +S +G +KG+ GE KG + + D + Sbjct: 2093 KVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNP 2152 Query: 5613 -FAGGLHFSGPKVEGGVKG-----GQIGLQ-------APGLS-VSGPQG--HLESGSGKV 5656 G +GP+ + G++G G +G APGL+ +GPQG L+ G+ Sbjct: 2153 GLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGET 2212 Query: 5657 TFPKMKIPKFTFSGRELVGREMGVDVHFPKAEASIQAGAGD-------------GEWEES 5703 P GR L G V + P + + G G Sbjct: 2213 GPP----------GRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRD 2262 Query: 5704 EVKLKKSKIKMPKFNFSK-------PKGKGGVTGSPEASISGSKGDLKSSKASLGSLEGE 5756 K P S PKG+ G TG+P ++ G G K K + G L G+ Sbjct: 2263 GASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPG-AKGEKGAPGGLAGD 2321 Query: 5757 AEAE 5760 E Sbjct: 2322 LVGE 2325 >gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo sapiens] Length = 1691 Score = 65.9 bits (159), Expect = 1e-09 Identities = 263/1043 (25%), Positives = 357/1043 (34%), Gaps = 182/1043 (17%) Query: 4876 GTLKGPEVDLKGPRLD----------FEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLHL 4925 G+ KG + D P LD F G P L+ P P PD ++ L Sbjct: 165 GSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPP---GPPGPLGPDGNMGL 221 Query: 4926 KAPKIGFSGPKLEGGEVDLKGPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKFGFGAK 4985 GF G K G+V L GP PS + ++ G PK KK G+K Sbjct: 222 -----GFQGEKGVKGDVGLPGPAGPPPS------TGELEFMG----FPKGKK-----GSK 261 Query: 4986 SPKADIKSPSLDVTVPEAELNLETPEISVGGKGKKSKFKMPKIH----------MSGPKI 5035 P ++ P L T G KG+K + +P + + GP Sbjct: 262 GEPGPKGFPG--ISGPPGFPGLGT----TGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPG 315 Query: 5036 KAKKQGFDLNVPGGEIDASLKAPDVDVNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEF 5095 + K+G L PG ++ D+ + GPD + +D G P ++ Sbjct: 316 QQGKKG-TLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKG 374 Query: 5096 DIKSPKFKAEAPLPS-PKLEGELQAPDLELSLPAIHVE-GLDIKAKAPKVKMPDVDISVP 5153 D + + +P P L G A + P + + G + +P D Sbjct: 375 DEGIQGLRGPSGVPGLPALSGVPGALGPQ-GFPGLKGDQGNPGRTTIGAAGLPGRD---- 429 Query: 5154 KIEGDLKGPKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVP 5213 L GP +P+ E L K ++ G+ Q P N+ LKG IKGD Sbjct: 430 ----GLPGPPGPPGPPSPEFETETLHNK-ESGFPGLRGEQG--PKGNLGLKG--IKGDSG 480 Query: 5214 SVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVK-----MEGGGAEVHAQLPSLEGDLRG 5268 +G V GP + P IG+PG+K GGA+ A P L G L Sbjct: 481 FCACDG-GVPNTGPPGE-PGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPL-- 536 Query: 5269 PDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPG 5328 GP G + S MP G +G + D VP + PG Sbjct: 537 ------GPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDG-VPGL----PG 585 Query: 5329 L-NLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRG-PSLQGDLAVSGDIKCPKVS 5386 L L G GG+ G G+ PG+ K + G P + G P L G + GD K Sbjct: 586 LPGLPGDGGQGFPGEKGL--PGLPGE-KGHPGPPGLPGNGLPGLPGPRGLPGD----KGK 638 Query: 5387 VGAP-DLSLEASEGSIKLPKMKLPQFGIST-PGSDLHVNAKGPQ-------------VSG 5431 G P L S+G I LP + +G S PG+ KG + G Sbjct: 639 DGLPGQQGLPGSKG-ITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKG 697 Query: 5432 ELKGPGVDVNLKGPRISAPNVDFNLEG----------------PKVKGSLGATGEIKGPT 5475 E PG+ + P P + L G P + GS GATG+I G Sbjct: 698 EPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGDIFG-- 755 Query: 5476 VGGGLPG-IGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGF 5534 G PG G+QGL G+ G D LPG + G K GL G + Sbjct: 756 AENGAPGEQGLQGLTGHKGFLG------DSGLPG---------LKGVHGKPGLLGPK--- 797 Query: 5535 HGAAPDISVKGPAFNMASPESDFGINLKGP-KIKGGADVSGGVSAPDISLGEGHLSVKGS 5593 G G +P S GP IKG + + G P IS GH KG+ Sbjct: 798 -GERGSPGTPGQVGQPGTPGS------SGPYGIKGKSGLPGAPGFPGIS---GHPGKKGT 847 Query: 5594 GGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQAPGL-SVSGPQGHLESG 5652 G+ KGP S + G G G+KG GL ++SGP+G E G Sbjct: 848 RGK-KGPPGS----IVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKG--EKG 900 Query: 5653 S-GKVTFPKMKIPKFTFSGRELVGREMGVDVHFPKAEASIQAGAGDGEWEESEVKLKKSK 5711 S G V FP + R L G P A GD V + + Sbjct: 901 SVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGD-RGNPGPVGIPSPR 959 Query: 5712 IKMPKFNFSKPKGKGGVTGSPEASISGSKGDLKSSKASLGSLEGEAEAEASSPKGKFSLF 5771 M KG G GS G +GD G G + Sbjct: 960 RPMSNLWLKGDKGSQGSAGS--NGFPGPRGD-------KGEAGRPGPPGLPGAPGLPGII 1010 Query: 5772 KSKKPRHRSNSFSDEREFSGPSTPTGTLEFEG--GEVSLEGGKVKGKHGKLKFGTFGGLG 5829 K + F R G +G F G GE +G ++G G GL Sbjct: 1011 KGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQG--IRGSPGLPGASGLPGLK 1068 Query: 5830 SKSKGHYEVTGSDDETGKLQGSG 5852 + E++GS G+ SG Sbjct: 1069 GDNGQTVEISGSPGPKGQPGESG 1091 Score = 47.0 bits (110), Expect = 6e-04 Identities = 109/398 (27%), Positives = 140/398 (35%), Gaps = 80/398 (20%) Query: 298 SGDHGKIKFPTMK-VPKFGVSTGREGQTPKAGLRVSAPEVSVGHKG--GKPGLT-IQAPQ 353 +G G + FP P G GQ G V AP G KG G PGL I PQ Sbjct: 127 NGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQ 186 Query: 354 LEVSVPSA----NIEGLEGKLKGPQITGPSLEGDLGLKGAK-PQGHIGVDASAPQIGGSI 408 P A GL+G P GP LG +G K +G +G+ A Sbjct: 187 GAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPA------- 239 Query: 409 TGPSVEVQAPDIDVQGPGSKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVPGVSGD 468 GP P S + M PK G+KGE G PG+SG Sbjct: 240 -GP-------------PPSTGELEFMGFPK-GKKGSKGE---------PGPKGFPGISGP 275 Query: 469 VSLPEIATGGLEGK--------MKGTKVKTPEMIIQKPKISMQDVDLSLGSPKL------ 514 P + T G +G+ + G + +Q P Q +LG P L Sbjct: 276 PGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPP-GQQGKKGTLGFPGLNGFQGI 334 Query: 515 ---KGDIKVSAPGVQGDVKGPQVALKGSRVDIETPNLEGTLTGPR----LGSPSGKTGTC 567 KGDI + P V D+ G + G+ D P L G L G L PSG G Sbjct: 335 EGQKGDIGLPGPDVFIDIDG--AVISGNPGDPGVPGLPG-LKGDEGIQGLRGPSGVPGLP 391 Query: 568 RISMSEVDLNVAA-PKVKGGVDVTLPRVEGKVKVPEVD-VRGPKVDVSAPDVEAHGPEWN 625 +S L P +KG G +P D + GP P PE+ Sbjct: 392 ALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPP-----SPEFE 446 Query: 626 LKMPKMKMPTFSTPGAKGEGPDVHMTLPKGDISISGPK 663 + K F PG +GE PKG++ + G K Sbjct: 447 TETLHNKESGF--PGLRGEQG------PKGNLGLKGIK 476 Score = 44.7 bits (104), Expect = 0.003 Identities = 106/401 (26%), Positives = 142/401 (35%), Gaps = 61/401 (15%) Query: 5156 EGDLKGPKVQ----ANLGAPDINIEGLDAKVKTPSFGISAPQV-SIPDVNVNLKGPKIKG 5210 E KG K + N+G P +G D KV S + P P V P + G Sbjct: 1089 ESGFKGTKGRDGLIGNIGFP--GNKGEDGKVGV-SGDVGLPGAPGFPGVAGMRGEPGLPG 1145 Query: 5211 DVPSVGLEGP--DVDLQGPEAKIKFPKFSMPKIGIPGVKMEGG-------GAEVHAQLPS 5261 G GP L GP+ FP G+PG K G G A LP Sbjct: 1146 SSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLN-GLPGTKGTHGTPGPSITGVPGPAGLPG 1204 Query: 5262 LEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPS 5321 +G+ P + + P PG+ + P + GP L G S+PS Sbjct: 1205 PKGEKGYPGIGIGAPGK----PGLRGQKGDRGFPGLQGP--------AGLPGAPGISLPS 1252 Query: 5322 MKVHAPG----LNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVS 5377 + PG L G G+ G G P ++ + + G P P + G Sbjct: 1253 LIAGQPGDPGRPGLDGERGRP--GPAGPPGPPGPSSNQGDTGDPGF----PGIPGPKGPK 1306 Query: 5378 GDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKG-PQVSGELKGP 5436 GD P S +L L+ G P F + TPG G P + G+ GP Sbjct: 1307 GDQGIPGFSGLPGELGLKGMRGE--------PGF-MGTPGKVGPPGDPGFPGMKGKA-GP 1356 Query: 5437 GVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPG 5496 L+G P + P G LG G P + G G GL+G+ +PG Sbjct: 1357 RGSSGLQGDPGQTPTAEAVQVPP---GPLGLPGIDGIPGLTGDPGAQGPVGLQGSKGLPG 1413 Query: 5497 IKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGA 5537 I LPG P G + P + GL+G GF GA Sbjct: 1414 IPGKDGPSGLPG-----PPGALGDPGLP-GLQGPP-GFEGA 1447 Score = 42.0 bits (97), Expect = 0.018 Identities = 120/450 (26%), Positives = 167/450 (37%), Gaps = 77/450 (17%) Query: 5242 GIPGVKMEGG-----GAEVHAQLPSLEGDLRGPDVKLEGPDVSLKG----PGVDLPSVNL 5292 G PG K G G+ V LP L+G P + V LKG PGV Sbjct: 840 GHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGL------VGLKGSPGSPGV------A 887 Query: 5293 SMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGL-NLSGVGGKMQVGGDGVKVPGID 5351 +P +SGP KG KG + V PG+ L G+ G + G +PG Sbjct: 888 GLPALSGP------KGE--KGSVGF------VGFPGIPGLPGIPGTRGLKG----IPG-- 927 Query: 5352 ATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQF 5411 +T K+ P P +GD G + P +L L+ +GS + Sbjct: 928 STGKMG---PSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGS----QGSAGSN 980 Query: 5412 GISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRIS-APNVDFNLEG-PKVKGSLGATG 5469 G P D A P G PG+ +KG P + G P +KGS G TG Sbjct: 981 GFPGPRGDKG-EAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITG 1039 Query: 5470 EIKGPTVGGGLPGIGVQGLEGNLQMPGIK-SSGCDVNL---PGVNVKLPTGQISGPEIKG 5525 P G G GL G +PG+K +G V + PG + G + + Sbjct: 1040 FPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRD 1099 Query: 5526 GLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGE 5585 GL G+ +GF G + G + ++ P + P G A + G P S + Sbjct: 1100 GLIGN-IGFPGNKGEDGKVGVSGDVGLPGA--------PGFPGVAGMRGEPGLPGSSGHQ 1150 Query: 5586 GHLSVKGSGG--EWKG-PQVSSALNLDTSKFAGGLHFS-GPKVEG-----GVKG--GQIG 5634 G + GS G KG P L+ G H + GP + G G+ G G+ G Sbjct: 1151 GAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKG 1210 Query: 5635 LQAPGLSVSGPQGHLESGSGKVTFPKMKIP 5664 G+ G G L G FP ++ P Sbjct: 1211 YPGIGIGAPGKPG-LRGQKGDRGFPGLQGP 1239 Score = 39.3 bits (90), Expect = 0.12 Identities = 67/246 (27%), Positives = 90/246 (36%), Gaps = 38/246 (15%) Query: 5410 QFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEG-PKVKGSLGAT 5468 Q + PG D + GP KG KG + AP ++G P + G G T Sbjct: 130 QGAVGFPGPDGYPGLLGPPGLPGQKGS------KGDPVLAPGSFKGMKGDPGLPGLDGIT 183 Query: 5469 GEIKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLK 5528 G P G + G GL+G PG G D N+ G + + G+K Sbjct: 184 GPQGAPGFPGAVGPAGPPGLQGPPGPPG--PLGPDGNMG-----------LGFQGEKGVK 230 Query: 5529 GSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGEGHL 5588 G +VG G A G M P+ KG K + G G+S P G G Sbjct: 231 G-DVGLPGPAGPPPSTGELEFMGFPKGK-----KGSKGEPGPKGFPGISGPPGFPGLGTT 284 Query: 5589 SVKGSGGEW--------KGPQVSSALNLDTSKFA--GGLHFSGPKVEGGVKG--GQIGLQ 5636 KG GE +GP S + + G L F G G++G G IGL Sbjct: 285 GEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLP 344 Query: 5637 APGLSV 5642 P + + Sbjct: 345 GPDVFI 350 Score = 39.3 bits (90), Expect = 0.12 Identities = 73/293 (24%), Positives = 112/293 (38%), Gaps = 51/293 (17%) Query: 202 GKTVIRLPSGSGAASPTGSAVDIRAGAISASGPELQGAGHSKLQVTMPGIKVGGSGV--- 258 G ++ +P +G P G G + P L+G K PG++ G +G+ Sbjct: 1190 GPSITGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRG---QKGDRGFPGLQ-GPAGLPGA 1245 Query: 259 -NVNAKGLDLGGRGGVQVPAVDISSSLGGRAVEV--QGPSLESGDHGKIKFPTMKVPK-- 313 ++ L G G P +D G A GPS GD G FP + PK Sbjct: 1246 PGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGP 1305 Query: 314 ---FGVS--TGREGQTPKAGLR-----------VSAP--------EVSVGHKG-----GK 344 G+ +G G+ G+R V P + G +G G Sbjct: 1306 KGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGD 1365 Query: 345 PGLTIQAPQLEVSVPSANIEGLEGKLKGPQITG-PSLEGDLGLKGAKPQGHIGVDASAPQ 403 PG T A ++V + G++G P +TG P +G +GL+G+K G G+ Sbjct: 1366 PGQTPTAEAVQVPPGPLGLPGIDGI---PGLTGDPGAQGPVGLQGSK--GLPGIPGKDGP 1420 Query: 404 IGGSITGPSVEVQAPDI-DVQGPGSKLNVPKMKVPKFSVSGAKGEETGIDVTL 455 G + GP + P + +QGP P + P F + G G+ + TL Sbjct: 1421 SG--LPGPPGALGDPGLPGLQGPPGFEGAPGQQGP-FGMPGMPGQSMRVGYTL 1470 Score = 38.5 bits (88), Expect = 0.20 Identities = 122/501 (24%), Positives = 171/501 (34%), Gaps = 99/501 (19%) Query: 226 AGAISASGPELQGAGHSKLQVTMPGIKVGGSGVNVNAKGLDLGGRGGVQVPAVDISSSLG 285 AG + SGP+ G S V PGI G G+ G RG +P Sbjct: 887 AGLPALSGPK--GEKGSVGFVGFPGIP-GLPGIP--------GTRGLKGIPGSTGKMGPS 935 Query: 286 GRAVEVQGPSLESGDHGKIKFPTMKVPKFGV-STGREGQTPKAGLR-VSAPEVSVGHKG- 342 GRA G + G+ G + P+ + P + G +G AG P G G Sbjct: 936 GRA-GTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGR 994 Query: 343 -GKPGLTIQAPQLEVSVPSAN----------IEGLEGKLKGPQITG-PSLEGDLGLKGAK 390 G PGL AP L + + I GL G ITG P + G+ G +G + Sbjct: 995 PGPPGLP-GAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIR 1053 Query: 391 PQGHIGVDASAPQIGGSITGPSVEVQAPDIDVQGPGSKLNVPKMKVPKFSVSGAKGEETG 450 + + P + G G +VE+ PG PK + + G KG + Sbjct: 1054 GSPGLPGASGLPGLKGD-NGQTVEISG------SPG-----PKGQPGESGFKGTKGRDGL 1101 Query: 451 I-DVTLP--TGEVTVPGVSGDVSLPEI----ATGGLEGK--MKGTK--------VKTPEM 493 I ++ P GE GVSGDV LP G+ G+ + G+ + +P + Sbjct: 1102 IGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGL 1161 Query: 494 IIQKPKISMQDVDLSLGSPKLKGDIKVSAPGVQGDVKGPQVALKGSRVDIETPNL----- 548 I K + G P KG P + G V GP L G + + P + Sbjct: 1162 IGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITG-VPGP-AGLPGPKGEKGYPGIGIGAP 1219 Query: 549 --------EGTLTGPRLGSPSGKTGTCRISMSEVDLNVAAPKVKGGVDVTLPRV------ 594 +G P L P+G G IS+ + + G+D R Sbjct: 1220 GKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPP 1279 Query: 595 -----------EGKVKVPEV-DVRGPKVDVSAPDVEAHGPEWNLKMPKMKMPTFSTPGAK 642 G P + +GPK D P E LK + + TPG Sbjct: 1280 GPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKV 1339 Query: 643 GEGPDVHMTLPKGDISISGPK 663 G P GD G K Sbjct: 1340 G---------PPGDPGFPGMK 1351 Score = 37.4 bits (85), Expect = 0.44 Identities = 73/289 (25%), Positives = 110/289 (38%), Gaps = 46/289 (15%) Query: 293 GPSLESGDHGKIKFPTMKVPKFGVST----GREGQTPKAGLRVSAPEVS--VGHKGGKPG 346 G + E G+ G+ P + P+ + + G GQ K G + P ++ G +G K Sbjct: 282 GTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGT-LGFPGLNGFQGIEGQKGD 340 Query: 347 LTIQAPQLEVSVPSANIEGLEGKLKGPQITG-PSLEGDLGLKGAK-PQGHIGVDASAPQI 404 + + P + + + A I G G P + G P L+GD G++G + P G G+ A + Sbjct: 341 IGLPGPDVFIDIDGAVISGNPGD---PGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVP 397 Query: 405 GGSITGPSVEVQAPDIDVQG-PGSKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVP 463 G GP QG PG K + +G G + G P Sbjct: 398 GA--LGP-----------QGFPGLKGDQGNPGRTTIGAAGLPGRD---------GLPGPP 435 Query: 464 GVSGDVSLPEIATGGLEGKMKGTKVKTPEMIIQKPK--ISMQDVDLSLGSPKLKGDIKVS 521 G G S PE T L K G E Q PK + ++ + G G + + Sbjct: 436 GPPGPPS-PEFETETLHNKESGFPGLRGE---QGPKGNLGLKGIKGDSGFCACDGGVPNT 491 Query: 522 APGVQGDVKGPQ-----VALKGSRVDIETPNLEGTLTGPRLGSPSGKTG 565 P + GP LKG+R D + +G P L P G +G Sbjct: 492 GPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSG 540 >gi|16357503 type IV alpha 6 collagen isoform B precursor [Homo sapiens] Length = 1690 Score = 65.9 bits (159), Expect = 1e-09 Identities = 263/1043 (25%), Positives = 357/1043 (34%), Gaps = 182/1043 (17%) Query: 4876 GTLKGPEVDLKGPRLD----------FEGPDAKLSGPSLKMPSLEISAPKVTAPDVDLHL 4925 G+ KG + D P LD F G P L+ P P PD ++ L Sbjct: 164 GSFKGMKGDPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPP---GPPGPLGPDGNMGL 220 Query: 4926 KAPKIGFSGPKLEGGEVDLKGPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKPKFGFGAK 4985 GF G K G+V L GP PS + ++ G PK KK G+K Sbjct: 221 -----GFQGEKGVKGDVGLPGPAGPPPS------TGELEFMG----FPKGKK-----GSK 260 Query: 4986 SPKADIKSPSLDVTVPEAELNLETPEISVGGKGKKSKFKMPKIH----------MSGPKI 5035 P ++ P L T G KG+K + +P + + GP Sbjct: 261 GEPGPKGFPG--ISGPPGFPGLGT----TGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPG 314 Query: 5036 KAKKQGFDLNVPGGEIDASLKAPDVDVNIAGPDAALKVDVKSPKTKKTMFGKMYFPDVEF 5095 + K+G L PG ++ D+ + GPD + +D G P ++ Sbjct: 315 QQGKKG-TLGFPGLNGFQGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKG 373 Query: 5096 DIKSPKFKAEAPLPS-PKLEGELQAPDLELSLPAIHVE-GLDIKAKAPKVKMPDVDISVP 5153 D + + +P P L G A + P + + G + +P D Sbjct: 374 DEGIQGLRGPSGVPGLPALSGVPGALGPQ-GFPGLKGDQGNPGRTTIGAAGLPGRD---- 428 Query: 5154 KIEGDLKGPKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVP 5213 L GP +P+ E L K ++ G+ Q P N+ LKG IKGD Sbjct: 429 ----GLPGPPGPPGPPSPEFETETLHNK-ESGFPGLRGEQG--PKGNLGLKG--IKGDSG 479 Query: 5214 SVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVK-----MEGGGAEVHAQLPSLEGDLRG 5268 +G V GP + P IG+PG+K GGA+ A P L G L Sbjct: 480 FCACDG-GVPNTGPPGE-PGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPL-- 535 Query: 5269 PDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPG 5328 GP G + S MP G +G + D VP + PG Sbjct: 536 ------GPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGEPGKDG-VPGL----PG 584 Query: 5329 L-NLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRG-PSLQGDLAVSGDIKCPKVS 5386 L L G GG+ G G+ PG+ K + G P + G P L G + GD K Sbjct: 585 LPGLPGDGGQGFPGEKGL--PGLPGE-KGHPGPPGLPGNGLPGLPGPRGLPGD----KGK 637 Query: 5387 VGAP-DLSLEASEGSIKLPKMKLPQFGIST-PGSDLHVNAKGPQ-------------VSG 5431 G P L S+G I LP + +G S PG+ KG + G Sbjct: 638 DGLPGQQGLPGSKG-ITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGSSGSKG 696 Query: 5432 ELKGPGVDVNLKGPRISAPNVDFNLEG----------------PKVKGSLGATGEIKGPT 5475 E PG+ + P P + L G P + GS GATG+I G Sbjct: 697 EPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGSPGLPGSKGATGDIFG-- 754 Query: 5476 VGGGLPG-IGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGF 5534 G PG G+QGL G+ G D LPG + G K GL G + Sbjct: 755 AENGAPGEQGLQGLTGHKGFLG------DSGLPG---------LKGVHGKPGLLGPK--- 796 Query: 5535 HGAAPDISVKGPAFNMASPESDFGINLKGP-KIKGGADVSGGVSAPDISLGEGHLSVKGS 5593 G G +P S GP IKG + + G P IS GH KG+ Sbjct: 797 -GERGSPGTPGQVGQPGTPGS------SGPYGIKGKSGLPGAPGFPGIS---GHPGKKGT 846 Query: 5594 GGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQAPGL-SVSGPQGHLESG 5652 G+ KGP S + G G G+KG GL ++SGP+G E G Sbjct: 847 RGK-KGPPGS----IVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKG--EKG 899 Query: 5653 S-GKVTFPKMKIPKFTFSGRELVGREMGVDVHFPKAEASIQAGAGDGEWEESEVKLKKSK 5711 S G V FP + R L G P A GD V + + Sbjct: 900 SVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGD-RGNPGPVGIPSPR 958 Query: 5712 IKMPKFNFSKPKGKGGVTGSPEASISGSKGDLKSSKASLGSLEGEAEAEASSPKGKFSLF 5771 M KG G GS G +GD G G + Sbjct: 959 RPMSNLWLKGDKGSQGSAGS--NGFPGPRGD-------KGEAGRPGPPGLPGAPGLPGII 1009 Query: 5772 KSKKPRHRSNSFSDEREFSGPSTPTGTLEFEG--GEVSLEGGKVKGKHGKLKFGTFGGLG 5829 K + F R G +G F G GE +G ++G G GL Sbjct: 1010 KGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQG--IRGSPGLPGASGLPGLK 1067 Query: 5830 SKSKGHYEVTGSDDETGKLQGSG 5852 + E++GS G+ SG Sbjct: 1068 GDNGQTVEISGSPGPKGQPGESG 1090 Score = 47.0 bits (110), Expect = 6e-04 Identities = 109/398 (27%), Positives = 140/398 (35%), Gaps = 80/398 (20%) Query: 298 SGDHGKIKFPTMK-VPKFGVSTGREGQTPKAGLRVSAPEVSVGHKG--GKPGLT-IQAPQ 353 +G G + FP P G GQ G V AP G KG G PGL I PQ Sbjct: 126 NGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKGDPGLPGLDGITGPQ 185 Query: 354 LEVSVPSA----NIEGLEGKLKGPQITGPSLEGDLGLKGAK-PQGHIGVDASAPQIGGSI 408 P A GL+G P GP LG +G K +G +G+ A Sbjct: 186 GAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGEKGVKGDVGLPGPA------- 238 Query: 409 TGPSVEVQAPDIDVQGPGSKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVPGVSGD 468 GP P S + M PK G+KGE G PG+SG Sbjct: 239 -GP-------------PPSTGELEFMGFPK-GKKGSKGE---------PGPKGFPGISGP 274 Query: 469 VSLPEIATGGLEGK--------MKGTKVKTPEMIIQKPKISMQDVDLSLGSPKL------ 514 P + T G +G+ + G + +Q P Q +LG P L Sbjct: 275 PGFPGLGTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPP-GQQGKKGTLGFPGLNGFQGI 333 Query: 515 ---KGDIKVSAPGVQGDVKGPQVALKGSRVDIETPNLEGTLTGPR----LGSPSGKTGTC 567 KGDI + P V D+ G + G+ D P L G L G L PSG G Sbjct: 334 EGQKGDIGLPGPDVFIDIDG--AVISGNPGDPGVPGLPG-LKGDEGIQGLRGPSGVPGLP 390 Query: 568 RISMSEVDLNVAA-PKVKGGVDVTLPRVEGKVKVPEVD-VRGPKVDVSAPDVEAHGPEWN 625 +S L P +KG G +P D + GP P PE+ Sbjct: 391 ALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPP-----SPEFE 445 Query: 626 LKMPKMKMPTFSTPGAKGEGPDVHMTLPKGDISISGPK 663 + K F PG +GE PKG++ + G K Sbjct: 446 TETLHNKESGF--PGLRGEQG------PKGNLGLKGIK 475 Score = 44.7 bits (104), Expect = 0.003 Identities = 106/401 (26%), Positives = 142/401 (35%), Gaps = 61/401 (15%) Query: 5156 EGDLKGPKVQ----ANLGAPDINIEGLDAKVKTPSFGISAPQV-SIPDVNVNLKGPKIKG 5210 E KG K + N+G P +G D KV S + P P V P + G Sbjct: 1088 ESGFKGTKGRDGLIGNIGFP--GNKGEDGKVGV-SGDVGLPGAPGFPGVAGMRGEPGLPG 1144 Query: 5211 DVPSVGLEGP--DVDLQGPEAKIKFPKFSMPKIGIPGVKMEGG-------GAEVHAQLPS 5261 G GP L GP+ FP G+PG K G G A LP Sbjct: 1145 SSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLN-GLPGTKGTHGTPGPSITGVPGPAGLPG 1203 Query: 5262 LEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPS 5321 +G+ P + + P PG+ + P + GP L G S+PS Sbjct: 1204 PKGEKGYPGIGIGAPGK----PGLRGQKGDRGFPGLQGP--------AGLPGAPGISLPS 1251 Query: 5322 MKVHAPG----LNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVS 5377 + PG L G G+ G G P ++ + + G P P + G Sbjct: 1252 LIAGQPGDPGRPGLDGERGRP--GPAGPPGPPGPSSNQGDTGDPGF----PGIPGPKGPK 1305 Query: 5378 GDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKG-PQVSGELKGP 5436 GD P S +L L+ G P F + TPG G P + G+ GP Sbjct: 1306 GDQGIPGFSGLPGELGLKGMRGE--------PGF-MGTPGKVGPPGDPGFPGMKGKA-GP 1355 Query: 5437 GVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPG 5496 L+G P + P G LG G P + G G GL+G+ +PG Sbjct: 1356 RGSSGLQGDPGQTPTAEAVQVPP---GPLGLPGIDGIPGLTGDPGAQGPVGLQGSKGLPG 1412 Query: 5497 IKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGA 5537 I LPG P G + P + GL+G GF GA Sbjct: 1413 IPGKDGPSGLPG-----PPGALGDPGLP-GLQGPP-GFEGA 1446 Score = 42.0 bits (97), Expect = 0.018 Identities = 120/450 (26%), Positives = 167/450 (37%), Gaps = 77/450 (17%) Query: 5242 GIPGVKMEGG-----GAEVHAQLPSLEGDLRGPDVKLEGPDVSLKG----PGVDLPSVNL 5292 G PG K G G+ V LP L+G P + V LKG PGV Sbjct: 839 GHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGL------VGLKGSPGSPGV------A 886 Query: 5293 SMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGL-NLSGVGGKMQVGGDGVKVPGID 5351 +P +SGP KG KG + V PG+ L G+ G + G +PG Sbjct: 887 GLPALSGP------KGE--KGSVGF------VGFPGIPGLPGIPGTRGLKG----IPG-- 926 Query: 5352 ATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQF 5411 +T K+ P P +GD G + P +L L+ +GS + Sbjct: 927 STGKMG---PSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGS----QGSAGSN 979 Query: 5412 GISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRIS-APNVDFNLEG-PKVKGSLGATG 5469 G P D A P G PG+ +KG P + G P +KGS G TG Sbjct: 980 GFPGPRGDKG-EAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITG 1038 Query: 5470 EIKGPTVGGGLPGIGVQGLEGNLQMPGIK-SSGCDVNL---PGVNVKLPTGQISGPEIKG 5525 P G G GL G +PG+K +G V + PG + G + + Sbjct: 1039 FPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPKGQPGESGFKGTKGRD 1098 Query: 5526 GLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGE 5585 GL G+ +GF G + G + ++ P + P G A + G P S + Sbjct: 1099 GLIGN-IGFPGNKGEDGKVGVSGDVGLPGA--------PGFPGVAGMRGEPGLPGSSGHQ 1149 Query: 5586 GHLSVKGSGG--EWKG-PQVSSALNLDTSKFAGGLHFS-GPKVEG-----GVKG--GQIG 5634 G + GS G KG P L+ G H + GP + G G+ G G+ G Sbjct: 1150 GAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITGVPGPAGLPGPKGEKG 1209 Query: 5635 LQAPGLSVSGPQGHLESGSGKVTFPKMKIP 5664 G+ G G L G FP ++ P Sbjct: 1210 YPGIGIGAPGKPG-LRGQKGDRGFPGLQGP 1238 Score = 39.3 bits (90), Expect = 0.12 Identities = 67/246 (27%), Positives = 90/246 (36%), Gaps = 38/246 (15%) Query: 5410 QFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEG-PKVKGSLGAT 5468 Q + PG D + GP KG KG + AP ++G P + G G T Sbjct: 129 QGAVGFPGPDGYPGLLGPPGLPGQKGS------KGDPVLAPGSFKGMKGDPGLPGLDGIT 182 Query: 5469 GEIKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLK 5528 G P G + G GL+G PG G D N+ G + + G+K Sbjct: 183 GPQGAPGFPGAVGPAGPPGLQGPPGPPG--PLGPDGNMG-----------LGFQGEKGVK 229 Query: 5529 GSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGEGHL 5588 G +VG G A G M P+ KG K + G G+S P G G Sbjct: 230 G-DVGLPGPAGPPPSTGELEFMGFPKGK-----KGSKGEPGPKGFPGISGPPGFPGLGTT 283 Query: 5589 SVKGSGGEW--------KGPQVSSALNLDTSKFA--GGLHFSGPKVEGGVKG--GQIGLQ 5636 KG GE +GP S + + G L F G G++G G IGL Sbjct: 284 GEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGFQGIEGQKGDIGLP 343 Query: 5637 APGLSV 5642 P + + Sbjct: 344 GPDVFI 349 Score = 39.3 bits (90), Expect = 0.12 Identities = 73/293 (24%), Positives = 112/293 (38%), Gaps = 51/293 (17%) Query: 202 GKTVIRLPSGSGAASPTGSAVDIRAGAISASGPELQGAGHSKLQVTMPGIKVGGSGV--- 258 G ++ +P +G P G G + P L+G K PG++ G +G+ Sbjct: 1189 GPSITGVPGPAGLPGPKGEKGYPGIGIGAPGKPGLRG---QKGDRGFPGLQ-GPAGLPGA 1244 Query: 259 -NVNAKGLDLGGRGGVQVPAVDISSSLGGRAVEV--QGPSLESGDHGKIKFPTMKVPK-- 313 ++ L G G P +D G A GPS GD G FP + PK Sbjct: 1245 PGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTGDPGFPGIPGPKGP 1304 Query: 314 ---FGVS--TGREGQTPKAGLR-----------VSAP--------EVSVGHKG-----GK 344 G+ +G G+ G+R V P + G +G G Sbjct: 1305 KGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGD 1364 Query: 345 PGLTIQAPQLEVSVPSANIEGLEGKLKGPQITG-PSLEGDLGLKGAKPQGHIGVDASAPQ 403 PG T A ++V + G++G P +TG P +G +GL+G+K G G+ Sbjct: 1365 PGQTPTAEAVQVPPGPLGLPGIDGI---PGLTGDPGAQGPVGLQGSK--GLPGIPGKDGP 1419 Query: 404 IGGSITGPSVEVQAPDI-DVQGPGSKLNVPKMKVPKFSVSGAKGEETGIDVTL 455 G + GP + P + +QGP P + P F + G G+ + TL Sbjct: 1420 SG--LPGPPGALGDPGLPGLQGPPGFEGAPGQQGP-FGMPGMPGQSMRVGYTL 1469 Score = 38.5 bits (88), Expect = 0.20 Identities = 122/501 (24%), Positives = 171/501 (34%), Gaps = 99/501 (19%) Query: 226 AGAISASGPELQGAGHSKLQVTMPGIKVGGSGVNVNAKGLDLGGRGGVQVPAVDISSSLG 285 AG + SGP+ G S V PGI G G+ G RG +P Sbjct: 886 AGLPALSGPK--GEKGSVGFVGFPGIP-GLPGIP--------GTRGLKGIPGSTGKMGPS 934 Query: 286 GRAVEVQGPSLESGDHGKIKFPTMKVPKFGV-STGREGQTPKAGLR-VSAPEVSVGHKG- 342 GRA G + G+ G + P+ + P + G +G AG P G G Sbjct: 935 GRA-GTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFPGPRGDKGEAGR 993 Query: 343 -GKPGLTIQAPQLEVSVPSAN----------IEGLEGKLKGPQITG-PSLEGDLGLKGAK 390 G PGL AP L + + I GL G ITG P + G+ G +G + Sbjct: 994 PGPPGLP-GAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIR 1052 Query: 391 PQGHIGVDASAPQIGGSITGPSVEVQAPDIDVQGPGSKLNVPKMKVPKFSVSGAKGEETG 450 + + P + G G +VE+ PG PK + + G KG + Sbjct: 1053 GSPGLPGASGLPGLKGD-NGQTVEISG------SPG-----PKGQPGESGFKGTKGRDGL 1100 Query: 451 I-DVTLP--TGEVTVPGVSGDVSLPEI----ATGGLEGK--MKGTK--------VKTPEM 493 I ++ P GE GVSGDV LP G+ G+ + G+ + +P + Sbjct: 1101 IGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGL 1160 Query: 494 IIQKPKISMQDVDLSLGSPKLKGDIKVSAPGVQGDVKGPQVALKGSRVDIETPNL----- 548 I K + G P KG P + G V GP L G + + P + Sbjct: 1161 IGPKGFPGFPGLHGLNGLPGTKGTHGTPGPSITG-VPGP-AGLPGPKGEKGYPGIGIGAP 1218 Query: 549 --------EGTLTGPRLGSPSGKTGTCRISMSEVDLNVAAPKVKGGVDVTLPRV------ 594 +G P L P+G G IS+ + + G+D R Sbjct: 1219 GKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPP 1278 Query: 595 -----------EGKVKVPEV-DVRGPKVDVSAPDVEAHGPEWNLKMPKMKMPTFSTPGAK 642 G P + +GPK D P E LK + + TPG Sbjct: 1279 GPPGPSSNQGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKV 1338 Query: 643 GEGPDVHMTLPKGDISISGPK 663 G P GD G K Sbjct: 1339 G---------PPGDPGFPGMK 1350 Score = 37.4 bits (85), Expect = 0.44 Identities = 73/289 (25%), Positives = 110/289 (38%), Gaps = 46/289 (15%) Query: 293 GPSLESGDHGKIKFPTMKVPKFGVST----GREGQTPKAGLRVSAPEVS--VGHKGGKPG 346 G + E G+ G+ P + P+ + + G GQ K G + P ++ G +G K Sbjct: 281 GTTGEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGT-LGFPGLNGFQGIEGQKGD 339 Query: 347 LTIQAPQLEVSVPSANIEGLEGKLKGPQITG-PSLEGDLGLKGAK-PQGHIGVDASAPQI 404 + + P + + + A I G G P + G P L+GD G++G + P G G+ A + Sbjct: 340 IGLPGPDVFIDIDGAVISGNPGD---PGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVP 396 Query: 405 GGSITGPSVEVQAPDIDVQG-PGSKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVP 463 G GP QG PG K + +G G + G P Sbjct: 397 GA--LGP-----------QGFPGLKGDQGNPGRTTIGAAGLPGRD---------GLPGPP 434 Query: 464 GVSGDVSLPEIATGGLEGKMKGTKVKTPEMIIQKPK--ISMQDVDLSLGSPKLKGDIKVS 521 G G S PE T L K G E Q PK + ++ + G G + + Sbjct: 435 GPPGPPS-PEFETETLHNKESGFPGLRGE---QGPKGNLGLKGIKGDSGFCACDGGVPNT 490 Query: 522 APGVQGDVKGPQ-----VALKGSRVDIETPNLEGTLTGPRLGSPSGKTG 565 P + GP LKG+R D + +G P L P G +G Sbjct: 491 GPPGEPGPPGPWGLIGLPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSG 539 >gi|154759255 collagen, type XXVIII precursor [Homo sapiens] Length = 1125 Score = 65.5 bits (158), Expect = 2e-09 Identities = 109/417 (26%), Positives = 156/417 (37%), Gaps = 50/417 (11%) Query: 5160 KGPK-VQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPSVGLE 5218 +GP+ V G P G K + S G + PQ L+G IKG+ +G Sbjct: 391 RGPEGVPGERGLPGEGFPG--PKGEKGSEGPTGPQ--------GLQGLSIKGEKGDIGPV 440 Query: 5219 GPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGDL--RGPDVKLEGP 5276 GP + P + + IG PG + G LP +G++ GP Sbjct: 441 GPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQG-----LPGSKGEVGQMGPTGPRGPV 495 Query: 5277 DVSLKGPGVDLPSVNL-SMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLSGVG 5335 + ++GP + S+ L P V G D KG +A +P + G Sbjct: 496 GIGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKG-------EAGLPGAR------GPEGPP 542 Query: 5336 GKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLE 5395 GK Q G G + + G P GP +G+ + G P S+ P + Sbjct: 543 GKGQPGPKGDEGKKGSKGNQGQRGLPGP--EGP--KGEPGIMGPFGMPGTSIPGPP-GPK 597 Query: 5396 ASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPR-ISAPNVDF 5454 G +P K + G+S G +GP + LKG G + GPR + P Sbjct: 598 GDRGGPGIPGFK-GEPGLSIRGPKGVQGPRGPVGAPGLKGDGYP-GVPGPRGLPGPPGPM 655 Query: 5455 NLEGPKVKGSLGATGE--IKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPGVNVK 5512 L G G GA GE ++GP G G+G QG +G+ G+ +K Sbjct: 656 GLRGV---GDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGIK 712 Query: 5513 LPTGQISGPEIKG----GLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPK 5565 G P KG GL G + G HG D+ KG + P S L+GPK Sbjct: 713 GEQGPQGFPGPKGTMGHGLPGQK-GEHGERGDVGKKGDKGEIGEPGSPGKQGLQGPK 768 Score = 65.1 bits (157), Expect = 2e-09 Identities = 127/465 (27%), Positives = 173/465 (37%), Gaps = 96/465 (20%) Query: 5206 PKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGD 5265 P IKG+ G +G + Q EA + P GIPG K + G P ++GD Sbjct: 259 PGIKGER---GPKGNPGNAQKGEAGERGPG------GIPGYKGDKG-ERGECGKPGIKGD 308 Query: 5266 LRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKG-PSLKGDLDASVPSMKV 5324 P GP KGP + ++GP D KG KG+ P Sbjct: 309 KGSP-----GP-YGPKGPR--------GIQGITGPPGDPGPKGFQGNKGEPGPPGPYGSP 354 Query: 5325 HAPGLNLSGVGGKM-QVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCP 5383 APG+ G+ G+ Q G G P + VG P P +G V G+ P Sbjct: 355 GAPGIGQQGIKGERGQEGRPGAPGP-------IGVGEPGQ----PGPRGPEGVPGERGLP 403 Query: 5384 KVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGV----D 5439 P + SEG ++ G+S G + GPQ G + PG+ + Sbjct: 404 GEGFPGPK-GEKGSEGPTGPQGLQ----GLSIKGEKGDIGPVGPQ--GPMGIPGIGSQGE 456 Query: 5440 VNLKGPRISAPNVDFNLEGPKVKGSLGATGEI--KGPTVGGGLPGIGVQGLEGNLQMPGI 5497 ++GP I P +GP +G G+ GE+ GPT G GIGVQG +G PG Sbjct: 457 QGIQGP-IGPPGP----QGPAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGPKGE---PG- 507 Query: 5498 KSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDF 5557 + LPG + G + G KG E G GA PE Sbjct: 508 -----SIGLPG------QPGVPGEDGAAGKKG-EAGLPGAR-------------GPEGPP 542 Query: 5558 GINLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGL 5617 G GPK G S G +G + G G P + + + G Sbjct: 543 GKGQPGPKGDEGKKGSKG--------NQGQRGLPGPEGPKGEPGIMGPFGMPGTSIPGP- 593 Query: 5618 HFSGPKVEGGVKGGQIGLQAPGLSVSGPQGHLESGSGKVTFPKMK 5662 GPK + G G PGLS+ GP+G ++ G V P +K Sbjct: 594 --PGPKGDRGGPGIPGFKGEPGLSIRGPKG-VQGPRGPVGAPGLK 635 Score = 48.9 bits (115), Expect = 1e-04 Identities = 103/385 (26%), Positives = 141/385 (36%), Gaps = 53/385 (13%) Query: 5459 PKVKGSLGATGEIKGPTVG-------GGLPGI-GVQGLEGNLQMPGIKSSGCDVNLPG-V 5509 P +KG G G G GG+PG G +G G PGIK D PG Sbjct: 259 PGIKGERGPKGNPGNAQKGEAGERGPGGIPGYKGDKGERGECGKPGIKG---DKGSPGPY 315 Query: 5510 NVKLPTG--QISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIK 5567 K P G I+GP G KG F G + GP + +P GI +G K + Sbjct: 316 GPKGPRGIQGITGPPGDPGPKG----FQGNKGEPGPPGPYGSPGAP----GIGQQGIKGE 367 Query: 5568 GGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGG 5627 G + G P I +GE G G +GP+ + + G F GPK E G Sbjct: 368 RGQEGRPGAPGP-IGVGE-----PGQPGP-RGPE-----GVPGERGLPGEGFPGPKGEKG 415 Query: 5628 VKG--GQIGLQAPGLSVSGPQGHLESGSGKVTFPKMKIPKFTFSGRELVGREMGVDVHFP 5685 +G G GLQ GLS+ G +G + + M IP G + G + + P Sbjct: 416 SEGPTGPQGLQ--GLSIKGEKGDIGPVGPQ---GPMGIPGIGSQGEQ--GIQGPIGPPGP 468 Query: 5686 KAEASIQAGAGDGEWEESEVKLKKSKIKMPKFNFSKPKGKGGVTGSP-EASISGSKGDLK 5744 + A GE + + + + PKG+ G G P + + G G Sbjct: 469 QGPAGQGLPGSKGEVGQMGPTGPRGPVGI---GVQGPKGEPGSIGLPGQPGVPGEDG--A 523 Query: 5745 SSKASLGSLEGEAEAEASSPKGKFSLFKSKKPRHRSNSFSDEREFSGPSTPTGTLEFEGG 5804 + K L G E KG+ K + + S +R GP P G G Sbjct: 524 AGKKGEAGLPGARGPEGPPGKGQPGP-KGDEGKKGSKGNQGQRGLPGPEGPKGEPGIM-G 581 Query: 5805 EVSLEGGKVKGKHGKLKFGTFGGLG 5829 + G + G G G GG G Sbjct: 582 PFGMPGTSIPGPPGPK--GDRGGPG 604 Score = 48.9 bits (115), Expect = 1e-04 Identities = 105/415 (25%), Positives = 154/415 (37%), Gaps = 71/415 (17%) Query: 293 GPSLESGDHGKIKFPTMKVPKFGVSTGREGQTPKAGLRVSAPEVSVGHKGGKPGLTIQAP 352 GP G G+ P P G EG T GL+ + KG K + P Sbjct: 389 GPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQ------GLSIKGEKGDIGPVGP 442 Query: 353 QLEVSVP---SANIEGLEGKLKGPQITGPSLEGDLGLKG-------AKPQGHIGVDASAP 402 Q + +P S +G++G + P GP+ +G G KG P+G +G+ P Sbjct: 443 QGPMGIPGIGSQGEQGIQGPIGPPGPQGPAGQGLPGSKGEVGQMGPTGPRGPVGIGVQGP 502 Query: 403 Q-IGGSITGPSVEVQAPDIDVQGPGSKLNVPKMKVPK----FSVSGAKGEETGIDVTLPT 457 + GSI P + G + +P + P+ G KG+E Sbjct: 503 KGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQ 562 Query: 458 GEVTVPGVSGDVSLPEIATGGLEGKMKGTKVKTPEMIIQKPKISMQDVDLSLGSPKLKGD 517 G+ +PG G P I G G M GT + P PK G P KG+ Sbjct: 563 GQRGLPGPEGPKGEPGIM--GPFG-MPGTSIPGP----PGPKGDRG----GPGIPGFKGE 611 Query: 518 IKVSAPGVQGDVKGPQVALKGSRVDIETPNLEGT----LTGPR-LGSPSGKTGTCRISMS 572 PG+ ++GP+ ++G R + P L+G + GPR L P G G + + Sbjct: 612 -----PGL--SIRGPK-GVQGPRGPVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDT 663 Query: 573 EVDLNVAAPKVKGGVDVTLPRVEGKVKVPEVDVRGPKVDVSAPDVEA-HGPEWNLKMPKM 631 P V+G + PR V +GPK D + GP Sbjct: 664 GAK---GEPGVRGPPGPSGPR--------GVGTQGPKGDTGQKGLPGPPGP--------- 703 Query: 632 KMPTFSTPGAKGEGPDVHMTLPKGDI--SISGPK-VNVEAPDVNLEGLGGKLKGP 683 P + + G KGE PKG + + G K + E DV +G G++ P Sbjct: 704 --PGYGSQGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGERGDVGKKGDKGEIGEP 756 Score = 42.0 bits (97), Expect = 0.018 Identities = 110/476 (23%), Positives = 160/476 (33%), Gaps = 139/476 (29%) Query: 2248 MPKFSMPGFKGE-------GPE----VDVNLPKADVDVSGPKVDVEVPDVSLEGPEGKLK 2296 +P PG KGE GP+ + + K D+ GP+ + +P + +G +G ++ Sbjct: 402 LPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQG-IQ 460 Query: 2297 GPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVDVSAPKLEGELKGPELDVKGPKLDAD 2356 GP + P +G P +GE+ ++ GP+ Sbjct: 461 GP----------------------IGPPGPQGPAGQGLPGSKGEV--GQMGPTGPRGPVG 496 Query: 2357 MPEVAVEGPNGKWKTPKFKMPDMHFKAPKISMPDLDLHLKSPKAKGEVDVDVPKLEGDLK 2416 + V+GP G + I +P P GE K E L Sbjct: 497 ---IGVQGPKG--------------EPGSIGLPG------QPGVPGEDGAAGKKGEAGLP 533 Query: 2417 GPHVDVSGPDIDIEGPEGK--LKGPKFKMPDMHFKAPNISMPDVDLNLKGPKIKGDVDVS 2474 G P GP+G KG K P +GPK Sbjct: 534 GARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGP-----------EGPK-------G 575 Query: 2475 VPEVEGKLEVPDMNI---RGPKVDVNAPDVQAPDWHLKMPKMKMPKFSMPGFKAEGPEVD 2531 P + G +P +I GPK D P + PGFK E P + Sbjct: 576 EPGIMGPFGMPGTSIPGPPGPKGDRGGPGI-------------------PGFKGE-PGLS 615 Query: 2532 VNLPKADVDISGPKVDIEGPDV------NIEGPEGKLKGPKLKMPEMNIKAPKISMPDFD 2585 + PK + GP+ + P + + GP G L GP M + D Sbjct: 616 IRGPKG---VQGPRGPVGAPGLKGDGYPGVPGPRG-LPGPPGPMGLRGVG---------D 662 Query: 2586 LHLKG-PKVKGDVDVSLPKVEGDLKGPEVDI--KGPKVDINAPDVGVQGPDWHLKMPKVK 2642 KG P V+G S P+ G +GP+ D KG P G QG Sbjct: 663 TGAKGEPGVRGPPGPSGPRGVG-TQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFP 721 Query: 2643 MPKFSM----PGFKGEGPDGDVKLPKADIDVSGPKVDIEGP----DVNIEGPEGKL 2690 PK +M PG KGE + + D+ G K +I P ++GP+G L Sbjct: 722 GPKGTMGHGLPGQKGEHGE------RGDVGKKGDKGEIGEPGSPGKQGLQGPKGDL 771 Score = 42.0 bits (97), Expect = 0.018 Identities = 93/390 (23%), Positives = 136/390 (34%), Gaps = 69/390 (17%) Query: 3499 PKGDINIEGPSMNIEGPDLNVEGPEGGLKGPKF-KMPDMNIKAPKISMPDIDLNLKGPKV 3557 P G ++G S+ E D+ GP+G + P + I+ P + P Sbjct: 419 PTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQGP----------IGPPGP 468 Query: 3558 KGDVDISLPKLEGDLKGPEVDIKGPKVDINAPDVDVHGPDWHLKMPKVKMPKFSMPGFKG 3617 +G LP +G EV GP + V G PK + +PG G Sbjct: 469 QGPAGQGLPGSKG-----EVGQMGPTGPRGPVGIGVQG-------PKGEPGSIGLPGQPG 516 Query: 3618 EGPEVDVTLPKADIDISGPNVDVDVPDVNIEGP--DAKLKGPKFKMPEMNIKAPKISMPD 3675 E K + + G P GP D KG K + + P+ P Sbjct: 517 VPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPE--GPK 574 Query: 3676 FDLNLKGP-KMKGDVVVSLPKVEGDLKGPEV-DIKGPKVDIDTPDINIEGSEGKFKGPKF 3733 + + GP M G + P +GD GP + KG P ++I G +G +GP+ Sbjct: 575 GEPGIMGPFGMPGTSIPGPPGPKGDRGGPGIPGFKG------EPGLSIRGPKG-VQGPRG 627 Query: 3734 KIPEMHLKA---PKISMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPE-------VDIKG 3783 + LK P + P GP V + K E ++GP V +G Sbjct: 628 PVGAPGLKGDGYPGVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQG 687 Query: 3784 PKVDI---------NAPDVDVQGPDWHLKMPKVKMPKFSM----PGFKGEGPDVDVNLPK 3830 PK D P QG PK +M PG KGE + + Sbjct: 688 PKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGE------R 741 Query: 3831 ADLDVSGPKVDIDVP----DVNIEGPEGKL 3856 D+ G K +I P ++GP+G L Sbjct: 742 GDVGKKGDKGEIGEPGSPGKQGLQGPKGDL 771 Score = 41.6 bits (96), Expect = 0.024 Identities = 101/433 (23%), Positives = 160/433 (36%), Gaps = 80/433 (18%) Query: 3006 IDVPDVGVQGPDWHLKMPKVK-MPKFSMPGFKGE-------GPD----VDVNLPKADLDV 3053 I V + G GP +P + +P PG KGE GP + + K D+ Sbjct: 380 IGVGEPGQPGPRGPEGVPGERGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGP 439 Query: 3054 SGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSL 3113 GP+ + +P + +G +G ++GP + P +G L Sbjct: 440 VGPQGPMGIPGIGSQGEQG-IQGP----------------------IGPPGPQGPAGQGL 476 Query: 3114 PKVEGDMKVPDVDIKGPKVDINAPDVDVQGPDWHLKMPKIKMPKISMPGFKGEGPEVDVN 3173 P +G+ V + GP+ + + VQG PK + I +PG G E Sbjct: 477 PGSKGE--VGQMGPTGPRGPVG---IGVQG-------PKGEPGSIGLPGQPGVPGEDGAA 524 Query: 3174 LPKADLDVSGPKVDVDVPDVNIEGP--DAKLKGPKFKMPEMNIKAPKISMPDLDLNLKGP 3231 K + + G + P GP D KG K + + P+ P + + GP Sbjct: 525 GKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPE--GPKGEPGIMGP 582 Query: 3232 -KMKGEVDVSLANVEGDLKGPAL-DIKG-PKIDVDAPDIDIHGPDAKLKGPKLKMPDMHV 3288 M G +GD GP + KG P + + P + GP + P LK D + Sbjct: 583 FGMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPK-GVQGPRGPVGAPGLK-GDGYP 640 Query: 3289 NMP---KISMPEIDLNLKG---SKLKGDVDVSGPKLEGDIKAPSLDIKGPEVD-----VS 3337 +P + P + L+G + KG+ V GP G + +GP+ D + Sbjct: 641 GVPGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGP--PGPSGPRGVGTQGPKGDTGQKGLP 698 Query: 3338 GP-------KLNIEGKSKKSRFKLPKFNFS-GSKVQTPEVDVKGKKPDIDITGPKVDINA 3389 GP I+G+ F PK G Q E G++ D+ G K +I Sbjct: 699 GPPGPPGYGSQGIKGEQGPQGFPGPKGTMGHGLPGQKGE---HGERGDVGKKGDKGEIGE 755 Query: 3390 PDVEVQGKVKGSK 3402 P + ++G K Sbjct: 756 PGSPGKQGLQGPK 768 Score = 38.1 bits (87), Expect = 0.26 Identities = 108/427 (25%), Positives = 154/427 (36%), Gaps = 105/427 (24%) Query: 1259 MPKFSMPGFKGE-GRE----------VDVNLPKADIDVSGPKVDVEVPDVSLEGPEG--- 1304 +P PG KGE G E + + K DI GP+ + +P + +G +G Sbjct: 402 LPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQG 461 Query: 1305 -------------KLKGPKFKMPEMHFKAPKISMPDVDLNLKGPKLKGDVDVSLPEVEGE 1351 L G K ++ +M P+ V + ++GPK + + LP G+ Sbjct: 462 PIGPPGPQGPAGQGLPGSKGEVGQMGPTGPR---GPVGIGVQGPKGEPG-SIGLP---GQ 514 Query: 1352 MKVPDVD-IKGPKVDISAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVKLPKAD 1410 VP D G K + P GP+ P PG KG+ + K + Sbjct: 515 PGVPGEDGAAGKKGEAGLP--GARGPE--------GPPGKGQPGPKGDEGKKGSKGNQGQ 564 Query: 1411 VDVSGPKMDAEVPDVNIEGPDAK--LKGPKFKMPEMSIKPQKISIPDVGLHLKGPKMKGD 1468 + GP EGP + + GP F MP SI P KGD Sbjct: 565 RGLPGP-----------EGPKGEPGIMGP-FGMPGTSIPGP-------------PGPKGD 599 Query: 1469 Y-DVTVPKVEGEIKAPDVDIKGPKVDINAPDVEVHGPDWHLKMPKVKMPKF-SMPGFKG- 1525 +P +GE P + I+GPK V GP + P +K + +PG +G Sbjct: 600 RGGPGIPGFKGE---PGLSIRGPK--------GVQGPRGPVGAPGLKGDGYPGVPGPRGL 648 Query: 1526 EGPEVDMNL-------PKADLGVSGPKVDIDVPDVNLEAPEGK-----LKGPKFKMPSMN 1573 GP M L K + GV GP V + P+G L GP P Sbjct: 649 PGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPP-GPPGYG 707 Query: 1574 IQTHKISMPDVGLNLKAPKLKTDVDVSLPKVEGDLKGPEIDVKAPKMDVNVGDIDIEGPE 1633 Q K G P K + LP +G+ G DV +G+ G + Sbjct: 708 SQGIKGEQGPQGF----PGPKGTMGHGLPGQKGE-HGERGDVGKKGDKGEIGEPGSPGKQ 762 Query: 1634 GKLKGPK 1640 G L+GPK Sbjct: 763 G-LQGPK 768 Score = 37.4 bits (85), Expect = 0.44 Identities = 85/335 (25%), Positives = 126/335 (37%), Gaps = 80/335 (23%) Query: 4657 MPKFSMPGFKGE-------GPD----VDVNLPKADIDVSGPKVDVDVPDVN------IEG 4699 +P PG KGE GP + + K DI GP+ + +P + I+G Sbjct: 402 LPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGPQGPMGIPGIGSQGEQGIQG 461 Query: 4700 PDAK----------LKGPKFKMPEMSIKAPKISMPDIDLNLKGPKVK-GDVDVT-LPKVE 4747 P L G K ++ +M P+ + + ++GPK + G + + P V Sbjct: 462 PIGPPGPQGPAGQGLPGSKGEVGQMGPTGPR---GPVGIGVQGPKGEPGSIGLPGQPGVP 518 Query: 4748 GDL----KGPEADIKGPKVDINTPDVDVHGP--DWHLKMPKVKMPKFSMPGFKGEGPDVD 4801 G+ K EA + G + P GP D K K + +PG +G Sbjct: 519 GEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKKGSKGNQGQRGLPGPEG------ 572 Query: 4802 VSLPKADIDVSGPKVDVDIPDVNIEGPDAKLKG-------PKFK-MPEINIKAPKISIPD 4853 PK + + GP +P +I GP KG P FK P ++I+ PK + Sbjct: 573 ---PKGEPGIMGP---FGMPGTSIPGPPGP-KGDRGGPGIPGFKGEPGLSIRGPK-GVQG 624 Query: 4854 VDLDLKGPKVKGDFDVSVPKVEGTLKGPEVDLKGPR-LDFEGPDAKLSGPSLKMPSLEIS 4912 + P +KGD VP G L GP GP L G P ++ P Sbjct: 625 PRGPVGAPGLKGDGYPGVPGPRG-LPGPP----GPMGLRGVGDTGAKGEPGVRGP----- 674 Query: 4913 APKVTAPDVDLHLKAPKIGFSGPKLEGGEVDLKGP 4947 P + P +G GPK + G+ L GP Sbjct: 675 -PGPSGPR--------GVGTQGPKGDTGQKGLPGP 700 Score = 37.0 bits (84), Expect = 0.58 Identities = 105/454 (23%), Positives = 161/454 (35%), Gaps = 86/454 (18%) Query: 378 PSLEGDLGLKGAK-PQGHIGVDASAPQIGGSITGPSVEVQAPDIDVQGPGSKLNVPKMKV 436 P G+ G+KG + P+G+ G Q + +GPG +P K Sbjct: 253 PGTHGNPGIKGERGPKGNPG-----------------NAQKGEAGERGPGG---IPGYKG 292 Query: 437 PK-----FSVSGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLEGKMKGTKVKTP 491 K G KG++ P G + G++G P G +G P Sbjct: 293 DKGERGECGKPGIKGDKGSPGPYGPKGPRGIQGITGPPGDP--GPKGFQGNKGEPGPPGP 350 Query: 492 EMIIQKPKISMQDVDLSLGS---PKLKGDIKVSAPGVQGDVKGPQVALKGSRVDIETPNL 548 P I Q + G P G I V PG G +GP+ + G R Sbjct: 351 YGSPGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQPGP-RGPE-GVPGER-------- 400 Query: 549 EGTLTGPRLGSPSGKTGTCRISMSEVDLNVAAPKVKGGVDVTLPRVEGKVKVPEVDVRGP 608 L G P G+ G+ + + ++ KG + P +G + +P + +G Sbjct: 401 --GLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPVGP--QGPMGIPGIGSQGE 456 Query: 609 KVDVSAPDVEAHGPEWNLKMPKMKMPTFSTPGAKGEGPDVHMTLPKGDISISGPKVNVEA 668 + + P + GP+ PG+KGE + T P+G + I E Sbjct: 457 Q-GIQGP-IGPPGPQGPAGQ--------GLPGSKGEVGQMGPTGPRGPVGIGVQGPKGEP 506 Query: 669 PDVNL---------EGLGGKLKG----PDVKLPDMSVKTPKISMPDVDLHVKGTK----V 711 + L +G GK KG P + P+ + P D KG+K Sbjct: 507 GSIGLPGQPGVPGEDGAAGK-KGEAGLPGARGPEGPPGKGQPG-PKGDEGKKGSKGNQGQ 564 Query: 712 KGEYDVTVPKLEGELKGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSVPGFKAEGPEVDV 771 +G PK E + GP P + GP PK +PGFK E P + + Sbjct: 565 RGLPGPEGPKGEPGIMGP---FGMPGTSIPGPPG----PKGDRGGPGIPGFKGE-PGLSI 616 Query: 772 NLPKADVDISGPKIDVTAPDVSIEEPEGKLKGPK 805 PK + GP+ V AP + + G + GP+ Sbjct: 617 RGPKG---VQGPRGPVGAPGLKGDGYPG-VPGPR 646 >gi|16554449 zonadhesin isoform 3 [Homo sapiens] Length = 2812 Score = 60.8 bits (146), Expect = 4e-08 Identities = 81/413 (19%), Positives = 139/413 (33%), Gaps = 59/413 (14%) Query: 2853 VDVTGP-KVEGDLKGPEVDLKGPKVDIDVPDVNVQGPDWHLKMPKMKMPKFSMPGFKAEG 2911 V TGP + G + P + K P V I+ P V + P + P + K ++ K Sbjct: 548 VSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTI 607 Query: 2912 PEVDVNLP----------------KADVDVSGPKVDVEGPDVNIEGPEGKLKGP------ 2949 P N+P K + P + E P ++ E P + P Sbjct: 608 PSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEE 667 Query: 2950 ---KFKMPEMNIKAPKIPMPDFDLHLKGPKVK-GDVDISLPKVEGDLKGPEVDIRGPQVD 3005 + P + + P IP + + P + + IS K + P + P + Sbjct: 668 TTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIP 727 Query: 3006 IDVPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLP-----KADLDVSGPKVDI 3060 + + + P + P + K P E P P K + P + Sbjct: 728 TEKSTISPEKPTTPTEKPTIPTEK---PTISPEKPTTPTEKPTISPEKLTIPTEKPTIPT 784 Query: 3061 DVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDM 3120 + P + E P + P E I K S+P ++ P +LP E Sbjct: 785 EKPTIPTEKPTISTEEPTTPTEETTISTEKPSIP-----MEKP--------TLPTEETTT 831 Query: 3121 KVPDVDIKGPKVDI--NAPDVDVQGPDWHLKMPKIKMPKISMPGFKGEGP---------E 3169 V + I K+ I P + + P + P I K+++P K P E Sbjct: 832 SVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEE 891 Query: 3170 VDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP 3222 ++ K + P + + P ++ E P + P E I K+++P Sbjct: 892 TTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIP 944 Score = 59.3 bits (142), Expect = 1e-07 Identities = 79/433 (18%), Positives = 145/433 (33%), Gaps = 58/433 (13%) Query: 771 VNLPKADVDISGPKIDVTAPDVSIEEPEGKLKGPKFKMPEMNIKVPKISMPDVDLHLKGP 830 ++ K V I P + P V E+P + P + I K +MP Sbjct: 565 ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPS-------- 616 Query: 831 NVKGEYDVTMPKVESEIKVPDVELKSAKMDIDVPDVEVQGPDWHLKMPKMKMPKFSMPGF 890 + P + + + + P + + P + P + K ++P Sbjct: 617 -----------------EKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTE 659 Query: 891 KAEGPEVDVNLPKADVDISGPKVGVEVPDVNIEGPEGKLKGPKFKMPE--MNIKAPKISM 948 + P + + P + E P + E P + P M E ++ + P IS Sbjct: 660 EPTTPTEETT-----TSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISP 714 Query: 949 PDVDLHMKGPKVKGEYDMTVP-KLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKFS 1007 + + P + E P K + P + P + + P + P I K + Sbjct: 715 EKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLT 774 Query: 1008 MPSLKGEGPEFDVNLSKANVDISAPKVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKM 1067 +P+ K + P + T P +S E P + + K Sbjct: 775 IPT------------EKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKP 822 Query: 1068 SLPDVDLDLKGPKMKGNVDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIP 1127 +LP + + IS K+ M+ P + P + + P + + L IP Sbjct: 823 TLPTEETTTSVEE----TTISTEKLTIPMEKPTISTEKPTIPTEKPTISPE----KLTIP 874 Query: 1128 KMKMPKFSMPSLKGEGP--EVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKM 1185 K+ ++P+ K P E ++ K + P + E P +S E P + P Sbjct: 875 TEKL---TIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPT 931 Query: 1186 PEMHFKTPKISMP 1198 E T K+++P Sbjct: 932 EETTISTEKLTIP 944 Score = 59.3 bits (142), Expect = 1e-07 Identities = 82/441 (18%), Positives = 149/441 (33%), Gaps = 35/441 (7%) Query: 1481 KAPDVDIKGPKVDINAPDVEVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDMNLP----- 1535 K P V I+ P V P V P + P + K ++P K P +P Sbjct: 568 KKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPT 627 Query: 1536 -----------KADLGVSGPKVDIDVPDVNLEAPEGKLKGPKFKMPSMNIQTHKISMPDV 1584 K + P + + P V E P + M I T K S+P Sbjct: 628 ILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTE 687 Query: 1585 GLNLKAPKLKTDVDVSLPKVEGDLKGPE---IDVKAPKMDVNVGDIDIEGPEGKLKGPKF 1641 ++ K ++ ++ E PE I + P + I E P + P Sbjct: 688 KPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTI 747 Query: 1642 KMPEMHFKAPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKVDIDAPDV 1701 + K + P + K + + K + P + + P + + P Sbjct: 748 PTEKPTISPEKPTTPTEKPTISPEK----LTIPTEKPTIPTEKPTIPTEKPTISTEEPTT 803 Query: 1702 EVHDPDWHLKMPKMKMPKFSMPGFK--AEGPEVDVNLPKADIDVSGPSVDTDAPDLDIEG 1759 + + P + M K ++P + E ++ K I + P++ T+ P + E Sbjct: 804 PTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEK 863 Query: 1760 PEGKLKGSKFKMPKLNIKAPKVSMPDVDLNLKGPKLKGEIDASVPELEGDLRGPQVDVKG 1819 P + KL I K ++P + + KL I P + + P + + Sbjct: 864 PTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKL--TIPTEKPTISPE--KPTISTEK 919 Query: 1820 PFVEAEVPDVDLECPDAKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGD-ADVSVP 1878 P + E P + E + + K +P + P IS + + + P + + + Sbjct: 920 PTIPTEKPTIPTE--ETTISTEKLTIPT---EKPTISPEKLTIPTEKPTISTEKPTIPTE 974 Query: 1879 KLEGDLTGPSVGVEVPDVELE 1899 KL P++ E P + E Sbjct: 975 KLTIPTEKPTIPTEKPTIPTE 995 Score = 58.9 bits (141), Expect = 1e-07 Identities = 80/434 (18%), Positives = 149/434 (34%), Gaps = 35/434 (8%) Query: 1954 PSVGVEVPDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVDLHLKG-----PKVKGDMD 2008 P+V +E P V E P + P + T K ++P ++ P K + Sbjct: 570 PTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTIL 629 Query: 2009 VSVPKVEGEMKV-----PDVDIKGPKMDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKA 2063 P + E P + + P + + P ++ P + K S+P K Sbjct: 630 TEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKP 689 Query: 2064 EGPEVDVNLPKADVVVSG--PKVDVEVPDVSLEGPEGKLKGPKLKMPEMHFKAPKISMPD 2121 P + + ++S P + E P + E P + + + K ++P Sbjct: 690 SIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPT 749 Query: 2122 VDLHLKGPKVKGDVD---VSLPKLEGDLTGPSVDVEVPDVELECPDAKLKGPKFKMPEMH 2178 + K + +S KL P++ E P + E P + P E Sbjct: 750 EKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETT 809 Query: 2179 FKTPKISMPDVNLNLKGPKVKGDMD---VSVPKVEGEMKVPDVDIRGPKVDIDAPDVDVH 2235 T K S+P L + ++ +S K+ M+ P + P + + P + Sbjct: 810 ISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPE 869 Query: 2236 GPDWHLKMPKMKMP--KFSMPGFKGEGP--EVDVNLPKADVDVSGPKVDVEVPDVSLEGP 2291 K+ +P K ++P K P E ++ K + P + E P +S E P Sbjct: 870 ---------KLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKP 920 Query: 2292 EGKLKGPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVDVSAPKLEGELKGPELDVKGP 2351 + P E T K+++P + K+ + P + E P + + Sbjct: 921 TIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKL--TIPTEKPTISTE--KPTIPTEKL 976 Query: 2352 KLDADMPEVAVEGP 2365 + + P + E P Sbjct: 977 TIPTEKPTIPTEKP 990 Score = 58.5 bits (140), Expect = 2e-07 Identities = 77/388 (19%), Positives = 135/388 (34%), Gaps = 22/388 (5%) Query: 1084 NVDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLK--- 1140 N IS K ++ P V P V + P + + S + P + K +MPS K Sbjct: 562 NPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTI 621 Query: 1141 -GEGPEVDVNLP-----KADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKMPEMHFKTPK 1194 E P + P K + P + E P V E P + M E T K Sbjct: 622 PSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEK 681 Query: 1195 ISMPDVDLHLKGPKVKGDVD---VSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWH 1251 S+P + K ++ +S K + P + + P + + + + P Sbjct: 682 PSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTP 741 Query: 1252 LKMPKM--KMPKFSMPGFKGEGREVDVNLPKADIDVSGPKVDVEVPDVSLEGPEGKLKGP 1309 + P + + P S + ++ K I P + E P + E P + P Sbjct: 742 TEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEP 801 Query: 1310 KFKMPEMHFKAPKISMPDVDLNLKGPKL-KGDVDVSLPEVEGEMKVPDVDIKGPKVDISA 1368 E K S+P ++ P L + S+ E + + ++ P + Sbjct: 802 TTPTEETTISTEKPSIP-----MEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEK 856 Query: 1369 PDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGP--EVDVKLPKADVDVSGPKMDAEVPDVN 1426 P + P + + K ++P K P E + K + P + E P ++ Sbjct: 857 PTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTIS 916 Query: 1427 IEGPDAKLKGPKFKMPEMSIKPQKISIP 1454 E P + P E +I +K++IP Sbjct: 917 TEKPTIPTEKPTIPTEETTISTEKLTIP 944 Score = 58.5 bits (140), Expect = 2e-07 Identities = 78/458 (17%), Positives = 159/458 (34%), Gaps = 53/458 (11%) Query: 850 PDVELKSAKMDIDVPDVEVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLP--KADVD 907 P + K + I+ P V + P + P + K ++ K P N+P K + Sbjct: 563 PTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIP 622 Query: 908 ISGPKVGVEVPDVNIEGPEGKLKGPKF--KMPEMNIKAPKISMPDVDLHMKGPKVKGEYD 965 P + E P + E P + P + P + + P + M+ P + E Sbjct: 623 SEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTE-- 680 Query: 966 MTVPKLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGP--EFDVNLS 1023 K + P + P + M+ + + P I K ++P+ K P + ++ Sbjct: 681 ----KPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPE 736 Query: 1024 KANVDISAPKVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKGPKMKG 1083 K P + T P +S E P + P ++ K ++P Sbjct: 737 KPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIP------------- 783 Query: 1084 NVDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLKGEG 1143 + P + P + + P + S + P + M K ++P+ Sbjct: 784 ------------TEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPT----- 826 Query: 1144 PEVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDLH 1203 E ++ + + + +E P +S E P + P ++ T K+++P Sbjct: 827 EETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIP----- 881 Query: 1204 LKGPKVK-GDVDVSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMPKF 1262 + P + + +S K+ + P + + P + + P + + P + + K Sbjct: 882 TEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKL 941 Query: 1263 SMPGFKGEGREVDVNLPKADIDVSGPKVDVEVPDVSLE 1300 ++P K ++ K I P + E P + E Sbjct: 942 TIPTEK-----PTISPEKLTIPTEKPTISTEKPTIPTE 974 Score = 58.2 bits (139), Expect = 2e-07 Identities = 78/393 (19%), Positives = 131/393 (33%), Gaps = 51/393 (12%) Query: 4031 KAPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVNLP----- 4085 K P V I+ P V + P V P + P + K ++P K P +P Sbjct: 568 KKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPT 627 Query: 4086 ----KADIDVSGPKVDIDTPDIDIHGPEGKLKGP---------KFKMPDLHLKAPKISMP 4132 K I P + + P I P + P + P + + P I Sbjct: 628 ILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTE 687 Query: 4133 EVDLNLKGPKMK-GDVDVSLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHLKMPKV 4191 + + + P + + +S K + P + + P + + + + P + P + Sbjct: 688 KPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTI 747 Query: 4192 KMPKFSMPGFKGEGPDVDVNLP-----KADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFK 4246 K P E P P K + P + + P + E P + P Sbjct: 748 PTEK---PTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTP 804 Query: 4247 MPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDI--DAPD 4304 E I K S+P ++ P +LP E E I K+ I + P Sbjct: 805 TEETTISTEKPSIP-----MEKP--------TLPTEETTTSVEETTISTEKLTIPMEKPT 851 Query: 4305 VDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVTLPKADIEISGPKVDI---------D 4355 + P + P + K ++P K P T+P + IS K+ I + Sbjct: 852 ISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPE 911 Query: 4356 APDVSIEGPDAKLKGPKFKMPEMNIKAPKISMP 4388 P +S E P + P E I K+++P Sbjct: 912 KPTISTEKPTIPTEKPTIPTEETTISTEKLTIP 944 Score = 57.8 bits (138), Expect = 3e-07 Identities = 82/418 (19%), Positives = 137/418 (32%), Gaps = 29/418 (6%) Query: 4613 ISLPKVEGDLKGPEVDIRDPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFK----GE 4668 IS K ++ P V P V + P + + P + P + K +MP K E Sbjct: 565 ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSE 624 Query: 4669 GPDVDVNLP-----KADIDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMSIKAPKISM 4723 P + P K I P + + P V E P + M E I K S+ Sbjct: 625 KPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSI 684 Query: 4724 PDIDLNLKGPKVKGDVDVTLPKVEGDLKGPE---ADIKGPKVDINTPDVDVHGPDWHLKM 4780 P ++ K ++ T+ E PE + P + + P + Sbjct: 685 PTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEK 744 Query: 4781 PKVKMPKFSMPGFKGEGPDVDVSLP-----KADIDVSGPKVDVDIPDVNIEGPDAKLKGP 4835 P + K P E P P K I P + + P + E P + P Sbjct: 745 PTIPTEK---PTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEP 801 Query: 4836 KFKMPEINIKAPKISIPDVDLDLKGPKV-KGDFDVSVPKVEGTLKGPEVDLKGPRLDFEG 4894 E I K SIP ++ P + + SV + + + + ++ P + E Sbjct: 802 TTPTEETTISTEKPSIP-----MEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEK 856 Query: 4895 PDAKLSGPSLKMPSLEISAPKVTAPDVDLHLKAPKIGFSGPKLEGGEVDLKGPKVEAPSL 4954 P P++ L I K+T P + + S KL + + P + Sbjct: 857 PTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKL---TIPTEKPTISPEKP 913 Query: 4955 DVHMDSPDINIEGPDVKIPKFKKPKFGFGAKSPKADIKSPSLDVTVPEAELNLETPEI 5012 + + P I E P + + + K I L + + ++ E P I Sbjct: 914 TISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTI 971 Score = 57.4 bits (137), Expect = 4e-07 Identities = 84/494 (17%), Positives = 168/494 (34%), Gaps = 49/494 (9%) Query: 2734 GDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKA 2793 G + P + K P V I+ P V P + P I K ++ K P N+P Sbjct: 558 GLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPS- 616 Query: 2794 DIDVSGPKVDVECPDVNIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDV 2853 P + E P + E P + P + T K ++P + T P + Sbjct: 617 ----EKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEE--PTTPTEETTT 670 Query: 2854 DVTGPKVEGDLKGPEVDLKGPKVDIDVPDVNVQGPDWHLKMPKMKMPKFSMPGFKAEGPE 2913 + P + + P + + P + + P ++++ + P + K ++P E P Sbjct: 671 SMEEPVI--PTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIP---TEKPT 725 Query: 2914 VDVNLPKADVDVSGPKVDVEGPDVNIEGPEGKLKGPKFKMPEMNIKAPKIPMPDFDLHLK 2973 + K+ + P E P + E P + P + I K+ +P Sbjct: 726 IPTE--KSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIP------- 776 Query: 2974 GPKVKGDVDISLPKVEGDLKGPEVDIRGPQVDIDVPDVGVQGPDWHLKMPKVKMPKFSMP 3033 + P + P + + P + + P + + K S+P Sbjct: 777 ------------------TEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIP 818 Query: 3034 GFKGEGPDVDVNLPKADLDVSGPKVDI--DVPDVNIEGPEGKLKGPKFKMPEMNIKAPKI 3091 K P + + +S K+ I + P ++ E P + P ++ I K+ Sbjct: 819 MEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKL 878 Query: 3092 SMPDIDLNLKGPKVK-GDMDVSLPKVEGDMKVPDVDIKGPKVDINAPDVDVQGPDWHLKM 3150 ++P + P + + +S K+ + P + + P + P + + P + Sbjct: 879 TIP-----TEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEE 933 Query: 3151 PKIKMPKISMPGFKGEGPEVDVNLP--KADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFK 3208 I K+++P K + +P K + P + + + E P + P Sbjct: 934 TTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993 Query: 3209 MPEMNIKAPKISMP 3222 ++ P P Sbjct: 994 TEKLTALRPPHPSP 1007 Score = 57.0 bits (136), Expect = 5e-07 Identities = 74/408 (18%), Positives = 147/408 (36%), Gaps = 35/408 (8%) Query: 4620 GDLKGPEVDIRDPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLP-- 4677 G + P + + P V I+ P V + P + P + K ++ K P N+P Sbjct: 558 GLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSE 617 Query: 4678 KADIDVSGPKVDVDVPDVNIEGPDAKLKGPKF--KMPEMSIKAPKISMPDIDLNLKGPKV 4735 K I P + + P + E P + P + P + + P + +++ P + Sbjct: 618 KPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVI 677 Query: 4736 KGDVDVTLPKVEGDLKGPEADIKGPKVDINTPDVDVHGPDWHLKMPKVKMPKFSMPGFKG 4795 + K + P + P + + + P + P + K ++P K Sbjct: 678 PTE------KPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKS 731 Query: 4796 EGPDVDVSLPKADIDVSGPKVDVDIPDVNIEGPDAKLKGPKFKMPEINIKAPKISIP--D 4853 +S K P + + P ++ E P + P ++ I K +IP Sbjct: 732 -----TISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEK 786 Query: 4854 VDLDLKGPKVKGDFDVSVPKVEGTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPSLEISA 4913 + + P + + + + P E T + + P + E P + + IS Sbjct: 787 PTIPTEKPTISTE-EPTTPTEETT-----ISTEKPSIPMEKPTLPTEETTTSVEETTIST 840 Query: 4914 PKVTAPDVDLHLKAPKIGFSGPKLEGGEVDLKGPKVEAPS--LDVHMDSPDINIEGPDVK 4971 K+T P ++ P I P + + + K+ P+ L + + P I IE + Sbjct: 841 EKLTIP-----MEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTIS 895 Query: 4972 IPKFKKP--KFGFGAKSPKADIKSPSLDV---TVPEAELNLETPEISV 5014 K P K + P + P++ T+P E + T ++++ Sbjct: 896 TEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTI 943 Score = 57.0 bits (136), Expect = 5e-07 Identities = 74/400 (18%), Positives = 137/400 (34%), Gaps = 39/400 (9%) Query: 3624 VTLPKADIDISGPNVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLNLKGP 3683 ++ K + I P+V + P V E P + P + I + K +MP + P Sbjct: 565 ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTI--P 622 Query: 3684 KMKGDVVVSLPKVEGDLKGPEVDIKGPKVDIDTPDINIEGSEGKFKGPKFKIPEMHLKAP 3743 K ++ P + + P + + P + + P + E + + E + Sbjct: 623 SEKPTILTEKPTIPSE--KPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTE 680 Query: 3744 KISMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPE---VDIKGPKVDINAPDVDVQGPDW 3800 K S+P ++ K ++ ++ E PE + + P + + + P Sbjct: 681 KPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTT 740 Query: 3801 HLKMPKVKMPKFSMPGFKGEGPDVDVNLP-----KADLDVSGPKVDIDVPDVNIEGPEGK 3855 + P + K P E P P K + P + + P + E P Sbjct: 741 PTEKPTIPTEK---PTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTIS 797 Query: 3856 LKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMQVPDLDIKGPKVD 3915 + P E I K S+P ++ P +LP E V + I K+ Sbjct: 798 TEEPTTPTEETTISTEKPSIP-----MEKP--------TLPTEETTTSVEETTISTEKLT 844 Query: 3916 I--NAPDVDVRGPDWHLKMPKIKMPKISMPGFKGEGP---------EVDVNLPKADLDVS 3964 I P + P + P I K+++P K P E ++ K + Sbjct: 845 IPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTE 904 Query: 3965 GPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP 4004 P + + P ++ E P + P E I K+++P Sbjct: 905 KPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIP 944 Score = 56.2 bits (134), Expect = 9e-07 Identities = 95/516 (18%), Positives = 176/516 (34%), Gaps = 74/516 (14%) Query: 1665 PKVKGDMDVSVPKVEGEMKVPDVDIKGPKVDIDAPDVEVHDPDWHLKMPKMKMPKFSMPG 1724 P V + G + P + K P V I+ P V P +PK K P Sbjct: 543 PPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKP----TVPKEK------PT 592 Query: 1725 FKAEGPEVDVNLPKADIDVSGPSVDTDAPDLDIEGPEGKLKGSKFKMPKLNIKAPKVSMP 1784 E P + P I P++ ++ P + E P + P + + P + Sbjct: 593 IPTEKPTISTEKP--TIPSEKPNMPSEKPTIPSEKPT-----ILTEKPTIPSEKPTIPSE 645 Query: 1785 DVDLNLKGPKLKGEIDASVPELEGDLRGPQVDVKGPFVEAEVPDVDLECPDAKLKGPKFK 1844 ++ + P + E + + P E ++ P + E P + E P + P Sbjct: 646 KPTISTEKPTVPTE-EPTTPTEE-----TTTSMEEPVIPTEKPSIPTEKPSIPTEKPTIS 699 Query: 1845 MPE--MHFKAPKISMPDVDLHLKGPKVKGD-ADVSVPKLEGDLTGPSVGVEVPDVELECP 1901 M E + + P IS + + P + + + +S K P++ E P + E P Sbjct: 700 MEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKP 759 Query: 1902 DAKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDVDVSVPKLEGDLTGPSVGVEVP 1961 + P + K ++P + P K + P + T ++ E P Sbjct: 760 TTPTEKPTISPEKLTIPTEKPTIPTEKPTI--PTEKPTISTEEPTTPTEET--TISTEKP 815 Query: 1962 DVELECPDAKLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVP 2021 + +E P + + E T K+++P M+ P Sbjct: 816 SIPMEKPTLPTEETTTSVEETTISTEKLTIP-------------------------MEKP 850 Query: 2022 DVDIKGPKMDIDAPDVDVHGPDWHLKMPKMKMP--KFSMPGFKAEGP--EVDVNLPKADV 2077 + + P + + P + K+ +P K ++P K P E ++ K + Sbjct: 851 TISTEKPTIPTEKPTISPE---------KLTIPTEKLTIPTEKPTIPIEETTISTEKLTI 901 Query: 2078 VVSGPKVDVEVPDVSLEGPEGKLKGPKLKMPEMHFKAPKISMPDVDLHLKGPKV-----K 2132 P + E P +S E P + P + E K+++P + K+ K Sbjct: 902 PTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEK 961 Query: 2133 GDVDVSLPKLEGD-LTGPSVDVEVPDVELECPDAKL 2167 + P + + LT P+ +P + P KL Sbjct: 962 PTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKL 997 Score = 55.8 bits (133), Expect = 1e-06 Identities = 79/439 (17%), Positives = 144/439 (32%), Gaps = 63/439 (14%) Query: 2532 VNLPKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPKISMPDFDLHLKGP 2591 ++ K V I P V E P V E P + P + + I + K +MP Sbjct: 565 ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPS-------- 616 Query: 2592 KVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKMPKVKMPKFSMPGF 2651 + P + + P + P + + P + P + K ++P Sbjct: 617 -----------------EKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTE 659 Query: 2652 KGEGPDGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKLKGPKFKMPE--MNIKAPKISM 2709 + P + + P + E P + E P + P M E ++ + P IS Sbjct: 660 EPTTP-----TEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISP 714 Query: 2710 PDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKI 2769 + + P + + P + P + P + + P + P + P I Sbjct: 715 EKPTIPTEKPTIPTEKSTISP------EKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTI 768 Query: 2770 KMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGPEGKWKSPKFKMPEMH 2829 K+++P K P + E P + E P + P E Sbjct: 769 SPEKLTIPTEK-------------------PTIPTEKPTIPTEKPTISTEEPTTPTEETT 809 Query: 2830 FKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPEVDLKGPKVDIDVPDVNVQGPD 2889 T K S+P L + V+ T E + ++ P + + P + + P Sbjct: 810 ISTEKPSIPMEKPTLPTEETTTSVEETTISTE----KLTIPMEKPTISTEKPTIPTEKPT 865 Query: 2890 WHLKMPKMKMPKFSMPGFKAEGP--EVDVNLPKADVDVSGPKVDVEGPDVNIEGPEGKLK 2947 + + K ++P K P E ++ K + P + E P ++ E P + Sbjct: 866 ISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTE 925 Query: 2948 GPKFKMPEMNIKAPKIPMP 2966 P E I K+ +P Sbjct: 926 KPTIPTEETTISTEKLTIP 944 Score = 55.5 bits (132), Expect = 2e-06 Identities = 87/434 (20%), Positives = 155/434 (35%), Gaps = 28/434 (6%) Query: 4149 VSLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFK----GE 4204 +S K ++ P V + P V + P + + P + P + K +MP K E Sbjct: 565 ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSE 624 Query: 4205 GPDVDVNLP-----KADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISM 4259 P + P K + P + + P V E P + M E I K S+ Sbjct: 625 KPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSI 684 Query: 4260 PDFDLHLKGPKVKGDVDVSLPKVEGDLKGPE---VDIKGPKVDIDAPDVDVHGPDWHLKM 4316 P + K ++ ++ E PE + + P + + + P + Sbjct: 685 PTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEK 744 Query: 4317 PKVKMPKFSMPGFKGEGPDVDVTL--PKADIEISGPKVDIDAPDVSIEGPDAKLKGPKFK 4374 P + K ++ K P T+ K I P + + P + E P + P Sbjct: 745 PTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTP 804 Query: 4375 MPEMNIKAPKISMPDIDFNLKGPKVKGDVD---VSLPKVEGDLKGPEIDIKGPSLDIDTP 4431 E I K S+P L + V+ +S K+ ++ P I + P++ + P Sbjct: 805 TEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKP 864 Query: 4432 DVNIEG---PEGKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGD-VDVSLPKVESD 4487 ++ E P KL P K P + I+ IS + + P + + +S K Sbjct: 865 TISPEKLTIPTEKLTIPTEK-PTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIP 923 Query: 4488 LKGPEVDIEGPEGKLKGPKFKMPDVHFKSPQISMSDIDLNLKGPKIKGDM-DISVPKLEG 4546 + P + E E + K +P + P IS + + + P I + I KL Sbjct: 924 TEKPTIPTE--ETTISTEKLTIPT---EKPTISPEKLTIPTEKPTISTEKPTIPTEKLTI 978 Query: 4547 DLKGPKVDVKGPKV 4560 + P + + P + Sbjct: 979 PTEKPTIPTEKPTI 992 Score = 55.1 bits (131), Expect = 2e-06 Identities = 75/396 (18%), Positives = 131/396 (33%), Gaps = 58/396 (14%) Query: 717 VTVPKLEGELKGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSVPGFKAEGPEVDVNLP-- 774 ++ K ++ P V + P V P + P + K ++P K P +P Sbjct: 565 ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSE 624 Query: 775 --------------KADVDISGPKIDVTAPDVSIEEPEGKLKGPKFKM------------ 808 K + P I P V EEP + M Sbjct: 625 KPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSI 684 Query: 809 ----PEMNIKVPKISMPDVDLHLKGPNVKGEYDVTMPKVESEIKVPDVELKSAKMDIDVP 864 P + + P ISM + + + P + E P + +E P + + + + + P Sbjct: 685 PTEKPSIPTEKPTISMEETIISTEKPTISPE----KPTIPTE--KPTIPTEKSTISPEKP 738 Query: 865 DVEVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVGVEVPDVNIEG 924 + P + P + K + P E P + K + P + E P + E Sbjct: 739 TTPTEKPTIPTEKPTISPEKPTTP---TEKPTISPE--KLTIPTEKPTIPTEKPTIPTEK 793 Query: 925 PEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGPKVKGEYDMT--------VPKLEGDLK 976 P + P E I K S+P M+ P + E T KL ++ Sbjct: 794 PTISTEEPTTPTEETTISTEKPSIP-----MEKPTLPTEETTTSVEETTISTEKLTIPME 848 Query: 977 GPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGP--EFDVNLSKANVDISAPKV 1034 P + P + + P + + I K ++P+ K P E ++ K + P + Sbjct: 849 KPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTI 908 Query: 1035 DTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLP 1070 P +S E P + P E K+++P Sbjct: 909 SPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIP 944 Score = 54.3 bits (129), Expect = 4e-06 Identities = 85/446 (19%), Positives = 147/446 (32%), Gaps = 62/446 (13%) Query: 899 VNLPKADVDISGPKVGVEVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGP 958 ++ K V I P V E P V E P + P + I + K +MP + P Sbjct: 565 ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPS-----EKP 619 Query: 959 KVKGEYDMTVPKLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGPEF 1018 + E P + P + + P + P I K ++P+ + P Sbjct: 620 TIPSE-------------KPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTE 666 Query: 1019 DVNLSKANVDISAPKVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKG 1078 + S + P + T P + E P + P M E K ++ + Sbjct: 667 ETTTS-----MEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTI-- 719 Query: 1079 PKMKGNVDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPS 1138 P K + I E P P + + P + + + P + K ++P+ Sbjct: 720 PTEKPTIPTEKSTISPEK--PTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPT 777 Query: 1139 LKGEGPEVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMP 1198 K P + E P + E P + P E T K S+P Sbjct: 778 EK-------------------PTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIP 818 Query: 1199 DVDLHLKGPKVKGDVD---VSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMP 1255 L + V+ +S K+ M+ P + + P + + P + + Sbjct: 819 MEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPE--------- 869 Query: 1256 KMKMP--KFSMPGFKG--EGREVDVNLPKADIDVSGPKVDVEVPDVSLEGPEGKLKGPKF 1311 K+ +P K ++P K E ++ K I P + E P +S E P + P Sbjct: 870 KLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTI 929 Query: 1312 KMPEMHFKAPKISMPDVDLNLKGPKL 1337 E K+++P + KL Sbjct: 930 PTEETTISTEKLTIPTEKPTISPEKL 955 Score = 53.5 bits (127), Expect = 6e-06 Identities = 78/438 (17%), Positives = 143/438 (32%), Gaps = 67/438 (15%) Query: 2149 PSVDVEVPDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMDVSVPK 2208 P+V +E P V E P + P + T K ++P N+ K Sbjct: 570 PTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEK----------- 618 Query: 2209 VEGEMKVPDVDIRGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKGEGPEVDVNLP 2268 P + P + + P + P + P + K ++P + P + Sbjct: 619 -------PTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETT-- 669 Query: 2269 KADVDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKT--PKISMPDVDFNLKGPKI 2326 + P + E P + E P + P M E T P IS + P I Sbjct: 670 ---TSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTI 726 Query: 2327 KGDVDVSAPKLEGELKGPELDVKGPKLDADMPEVAVEGPNGKWKTPKFKMPDMHFKAPKI 2386 + +P + P + P + + P ++ E P TP K P I Sbjct: 727 PTEKSTISP------EKPTTPTEKPTIPTEKPTISPEKPT----TPTEK--------PTI 768 Query: 2387 SMPDLDLHLKSPKAKGEVDVDVPKLEGDLKGPHVDVSGPDIDIEGPEGKLKGPKF--KMP 2444 S L + + P E P + P I E P + + P Sbjct: 769 SPEKLTIPTEKPTIPTE-------------KPTIPTEKPTISTEEPTTPTEETTISTEKP 815 Query: 2445 DMHFKAPNISMPDVDLNLKGPKIKGDVDVSVPEVEGKLEVPDMNIRGPKVDVNAPDVQAP 2504 + + P + + +++ + +S ++ +E P ++ P + P + Sbjct: 816 SIPMEKPTLPTEETTTSVE------ETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPE 869 Query: 2505 DWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDIEGPDVNIEGPEGKLKG 2564 + K+ +P P E E ++ K + P + E P ++ E P + Sbjct: 870 KLTIPTEKLTIPT-EKPTIPIE--ETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEK 926 Query: 2565 PKLKMPEMNIKAPKISMP 2582 P + E I K+++P Sbjct: 927 PTIPTEETTISTEKLTIP 944 Score = 52.4 bits (124), Expect = 1e-05 Identities = 72/414 (17%), Positives = 140/414 (33%), Gaps = 57/414 (13%) Query: 1227 PDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMPKFSMPGFKGEGREVDVNLPKADIDVS 1286 P + K P + I+ P V + P + P + K + ++ K I Sbjct: 563 PTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPT------------ISTEKPTIPSE 610 Query: 1287 GPKVDVEVPDVSLEGPEGKLKGPKF--KMPEMHFKAPKISMPDVDLNLKGPKLKGDVDVS 1344 P + E P + E P + P + P + + P IS + + P + Sbjct: 611 KPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTE---- 666 Query: 1345 LPEVEGEMKVPDVDIKGPKVDISAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDV 1404 E M+ P + + P + P + P ++ + K P E P + Sbjct: 667 --ETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEK---PTISPEKPTIPT 721 Query: 1405 KLP-----KADVDVSGPKMDAEVPDVNIEGPDAKLKGPKFKMPEMSIKPQKISIPDVGLH 1459 + P K+ + P E P + E P + P + +I P+K++IP Sbjct: 722 EKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIP----- 776 Query: 1460 LKGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKVDINAPDVEVHGPDWHLKMPKVKMPKFS 1519 T+P + P + + P + P + P + M K + Sbjct: 777 --------TEKPTIP-----TEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPT 823 Query: 1520 MPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPDVNLEAPEGKLKGPKFKMPSMNIQTHKI 1579 +P E ++ + + + ++ P ++ E P + P + I T K+ Sbjct: 824 LP-----TEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKL 878 Query: 1580 SMPDVGLNLKAPKLK-TDVDVSLPKVEGDLKGPEIDVKAPKMDVNVGDIDIEGP 1632 ++P + P + + +S K+ + P I + P + I E P Sbjct: 879 TIP-----TEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKP 927 Score = 52.4 bits (124), Expect = 1e-05 Identities = 89/435 (20%), Positives = 148/435 (34%), Gaps = 39/435 (8%) Query: 2070 VNLPKADVVVSGPKVDVEVPDVSLEGPEGKLKGPKLKMPEMHFKAPKISMPDVDLHLKGP 2129 ++ K V + P V E P V E P + P + + + K +MP + P Sbjct: 565 ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTI--P 622 Query: 2130 KVKGDVDVSLPKLEGD-----LTGPSVDVEVPDVELECPDAKLKGPKFKMPEMHFKTPKI 2184 K + P + + P++ E P V E P + M E T K Sbjct: 623 SEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKP 682 Query: 2185 SMPDVNLNLKGPKVKGDMD---VSVPKVEGEMKVPDVDIRGPKVDIDAPDVDVHGPDWHL 2241 S+P ++ K M+ +S K + P + P + + + P Sbjct: 683 SIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPT 742 Query: 2242 KMPKMKMPKFSMPGFKGEGPEVDVNLP-----KADVDVSGPKVDVEVPDVSLEGPEGKLK 2296 + P + K P E P P K + P + E P + E P + Sbjct: 743 EKPTIPTEK---PTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTE 799 Query: 2297 GPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVD---VSAPKLEGELKGPELDVKGPKL 2353 P E T K S+P L + V+ +S KL ++ P + + P + Sbjct: 800 EPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTI 859 Query: 2354 DADMPEVAVEG---PNGKWKTPKFKMPDMHFKAPKISMPDLDLHLKSPKAKGEVDVDVPK 2410 + P ++ E P K P K P + + IS L + P K + + P Sbjct: 860 PTEKPTISPEKLTIPTEKLTIPTEK-PTIPIEETTISTEKLTI----PTEKPTISPEKPT 914 Query: 2411 LEGDLKGPHVDVSGPDIDIEGPEGKLKGPKFKMPDMHFKAPNISMPDVDLNLKGPKIKGD 2470 + + P + P I E E + K +P + P IS + + + P I + Sbjct: 915 I--STEKPTIPTEKPTIPTE--ETTISTEKLTIPT---EKPTISPEKLTIPTEKPTISTE 967 Query: 2471 VDVSVPEVEGKLEVP 2485 E KL +P Sbjct: 968 KPTIPTE---KLTIP 979 Score = 52.0 bits (123), Expect = 2e-05 Identities = 77/493 (15%), Positives = 159/493 (32%), Gaps = 47/493 (9%) Query: 3772 GDLKGPEVDIKGPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKA 3831 G + P + K P V I P V + P + P + K ++ K P N+P Sbjct: 558 GLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPS- 616 Query: 3832 DLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDM 3891 P + + P + E P + P + I K ++P + + M Sbjct: 617 ----EKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSM 672 Query: 3892 DVSLPKVEGDMQVPDLDIKGPKVDINAPDVDVRGPDWHLKMPKIKMPKISMPGFKGEGP- 3950 + + E P + + P + P + + + P I K ++P K P Sbjct: 673 EEPVIPTE----KPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPT 728 Query: 3951 -EVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLH 4009 + ++ K P + + P ++ E P + P ++ I K ++P Sbjct: 729 EKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIP----- 783 Query: 4010 LKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFS 4069 + P + + P + + P + P + M K + Sbjct: 784 --------------------TEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPT 823 Query: 4070 MPGFKGEGPEVDVNLPKADIDVSGPKVDIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKI 4129 +P E ++ + I + ++ P I P + P L + K+ Sbjct: 824 LP-----TEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKL 878 Query: 4130 SMPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHLKMP 4189 ++P K + +S K+ + P + + P + + P + + P + Sbjct: 879 TIP----TEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEET 934 Query: 4190 KVKMPKFSMPGFKGEGPDVDVNLP--KADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKM 4247 + K ++P K + +P K + P + + + E P + P Sbjct: 935 TISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPT 994 Query: 4248 PEMNIKAPKISMP 4260 ++ P P Sbjct: 995 EKLTALRPPHPSP 1007 Score = 51.2 bits (121), Expect = 3e-05 Identities = 94/511 (18%), Positives = 170/511 (33%), Gaps = 58/511 (11%) Query: 3394 VQGKVKGSKFKMPFLSISS---PKVSMPDVELNLKSPKVKGDLDIAGPNLEGDFKGPKVD 3450 +QG S M F+ I+ P +P++ P V G + P + Sbjct: 513 IQGSNTASVVAMGFILINPGTCPVKVLPEL------PPVSPVSSTGPSETTGLTENPTIS 566 Query: 3451 IKAPEVNLNAPDVDVHGPDWNLKMPKMKMPKFSVSGLK------------------AEGP 3492 K P V++ P V P + P + K ++S K +E P Sbjct: 567 TKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKP 626 Query: 3493 DVAVDLP-----KGDINIEGPSMNIEGPDLNVEGPEGGLKGPKFKMPDMNIKAPKISMPD 3547 + + P K I E P+++ E P + E P + M + I K S+P Sbjct: 627 TILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPT 686 Query: 3548 IDLNLKGPKVKGDVDISLPKLEGDLKGPE---VDIKGPKVDINAPDVDVHGPDWHLKMPK 3604 ++ K ++ ++ E PE + + P + + P + P Sbjct: 687 EKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPT 746 Query: 3605 VKMPKFSMPGFKGEGPEVDVTL--PKADIDISGPNVDVDVPDVNIEGPDAKLKGPKFKMP 3662 + K ++ K P T+ K I P + + P + E P + P Sbjct: 747 IPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTE 806 Query: 3663 EMNIKAPKISMPDFDLNLKGPKMKGDV---VVSLPKVEGDLKGPEVDIKGPKVDIDTPDI 3719 E I K S+P L + V +S K+ ++ P + + P + + P I Sbjct: 807 ETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTI 866 Query: 3720 NIEGSEGKFKGPKFKIPEMHLKAPKISMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPEV 3779 + E K IP L P P I + + +S K+ + P + Sbjct: 867 SPE---------KLTIPTEKLTIP-TEKPTIPIE--------ETTISTEKLTIPTEKPTI 908 Query: 3780 DIKGPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPK 3839 + P + P + + P + + K ++P K + +P +S K Sbjct: 909 SPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEK 968 Query: 3840 VDIDVPDVNIEGPEGKLKGPKFKMPEMNIKA 3870 I + I + + K +P + A Sbjct: 969 PTIPTEKLTIPTEKPTIPTEKPTIPTEKLTA 999 Score = 46.2 bits (108), Expect = 0.001 Identities = 94/486 (19%), Positives = 178/486 (36%), Gaps = 65/486 (13%) Query: 239 AGHSK-LQVTMPGIKVGGSGVNVNAKGLDLGGRGGVQV------PAVDISSSLGGRAVE- 290 +GH + +Q+ GI+ G + +V A G L G V P V SS G Sbjct: 500 SGHQQPMQLIFKGIQ-GSNTASVVAMGFILINPGTCPVKVLPELPPVSPVSSTGPSETTG 558 Query: 291 -VQGPSLESGDHGKIKFPTMKVPKFGVSTGREGQTPKAGLRVSAPEVSVGHKGGKPGLTI 349 + P++ + K PT+ + K V+T + PK + + ++ + KP + Sbjct: 559 LTENPTIST------KKPTVSIEKPSVTTEKP-TVPKEKPTIPTEKPTISTE--KPTIPS 609 Query: 350 QAPQLEVSVPSANIEGLEGKLKGPQITG--PSLEGDLGLKGAKPQGHIGVDASAP--QIG 405 + P + P+ E + P I P++ + + + + P + Sbjct: 610 EKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETT 669 Query: 406 GSITGPSVEVQAPDIDVQGPGSKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVPGV 465 S+ P + + P I + P P + + + +S K + T+PT + T+P Sbjct: 670 TSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTE 729 Query: 466 SGDVSLPEIATGGLEGKMKGTKVKTPEMIIQKPKISMQDVDLSLGSPKLKGDIKVSAPGV 525 +S PE T T + P + +KP IS + P + + K++ P Sbjct: 730 KSTIS-PEKPT---------TPTEKPTIPTEKPTISPEKPTTPTEKPTISPE-KLTIP-- 776 Query: 526 QGDVKGPQVALKGSRVDIETPNLEGTLTGPRLGSPSGKTGTCRISMSEVDLNVAAPKVKG 585 + P + + + E P + P+ T IS + + + P Sbjct: 777 ---TEKPTIPTEKPTIPTEKPTIS-------TEEPTTPTEETTISTEKPSIPMEKP---- 822 Query: 586 GVDVTLPRVEGKVKVPEVDVRGPK--VDVSAPDVEAHGPEWNLKMPKMKMPTFSTPGAKG 643 TLP E V E + K + + P + P + P + + P K Sbjct: 823 ----TLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKL 878 Query: 644 EGPDVHMTLPKGDISIS---------GPKVNVEAPDVNLEGLGGKLKGPDVKLPDMSVKT 694 P T+P + +IS P ++ E P ++ E + P + + ++ T Sbjct: 879 TIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTIST 938 Query: 695 PKISMP 700 K+++P Sbjct: 939 EKLTIP 944 Score = 45.1 bits (105), Expect = 0.002 Identities = 83/440 (18%), Positives = 145/440 (32%), Gaps = 63/440 (14%) Query: 4903 SLKMPSLEISAPKVTAPDVDLHLKAPKIGFSGPKLEGGEVDLKGPKVEAPSLDVHMDSPD 4962 S K P++ I P VT + + P I P + + + K PS + P Sbjct: 566 STKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPS-----EKPT 620 Query: 4963 INIEGPDVKIPKFKKPKFGFGAKSPKADIKSPSLDV---TVPEAELNLETPEISVGGKGK 5019 I E P + K P ++ P + P++ TVP E T E + + Sbjct: 621 IPSEKPTILTEKPTIP-----SEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEP 675 Query: 5020 KSKFKMPKIHMSGPKIKAKKQGFDLNVPGGEIDASLKAPDVD-----VNIAGPDAALKVD 5074 + P I P I +K + E S + P + + P + Sbjct: 676 VIPTEKPSIPTEKPSIPTEKPTISME----ETIISTEKPTISPEKPTIPTEKPTIPTEKS 731 Query: 5075 VKSPKTKKTMFGKMYFPDVEFDIKSPKFKAEAPLPSPKLEGELQAPDLELSLPAIHVEGL 5134 SP+ T K P E P SP + P P I E L Sbjct: 732 TISPEKPTTPTEK------------PTIPTEKPTISP------EKPTTPTEKPTISPEKL 773 Query: 5135 DIKAKAPKV--KMPDVDISVPKIEGDLKGPKVQANLGAPDINIEGLDAKVKTPSFGISAP 5192 I + P + + P + P I + P E + PS + P Sbjct: 774 TIPTEKPTIPTEKPTIPTEKPTISTE-----------EPTTPTEETTISTEKPSIPMEKP 822 Query: 5193 QVSIPDVNVNLKGPKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGG 5252 + + +++ I + ++ +E P + + P + P S K+ IP K+ Sbjct: 823 TLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPT 882 Query: 5253 -------AEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGV--DLPSVNLSMPKVSGPDLD 5303 E L P + E P +S + P + + P++ +S L Sbjct: 883 EKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLT 942 Query: 5304 LNLKGPSLKGDLDASVPSMK 5323 + + P++ + ++P+ K Sbjct: 943 IPTEKPTISPE-KLTIPTEK 961 Score = 33.9 bits (76), Expect = 4.9 Identities = 29/152 (19%), Positives = 59/152 (38%), Gaps = 15/152 (9%) Query: 5183 KTPSFGISAPQVSIPDVNVNLKGPKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIG 5242 + P+ P VSI +V + P + + P++ E P + + P + P K Sbjct: 561 ENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPT 620 Query: 5243 IPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDL 5302 IP K + + P++ + P + E P +S + P+V P + Sbjct: 621 IPSEK-----PTILTEKPTIPSE--KPTIPSEKPTIS-----TEKPTVPTEEPTTPTEET 668 Query: 5303 DLNLKGPSL---KGDLDASVPSMKVHAPGLNL 5331 +++ P + K + PS+ P +++ Sbjct: 669 TTSMEEPVIPTEKPSIPTEKPSIPTEKPTISM 700 >gi|27881494 zonadhesin isoform 6 [Homo sapiens] Length = 2721 Score = 60.8 bits (146), Expect = 4e-08 Identities = 81/413 (19%), Positives = 139/413 (33%), Gaps = 59/413 (14%) Query: 2853 VDVTGP-KVEGDLKGPEVDLKGPKVDIDVPDVNVQGPDWHLKMPKMKMPKFSMPGFKAEG 2911 V TGP + G + P + K P V I+ P V + P + P + K ++ K Sbjct: 548 VSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTI 607 Query: 2912 PEVDVNLP----------------KADVDVSGPKVDVEGPDVNIEGPEGKLKGP------ 2949 P N+P K + P + E P ++ E P + P Sbjct: 608 PSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEE 667 Query: 2950 ---KFKMPEMNIKAPKIPMPDFDLHLKGPKVK-GDVDISLPKVEGDLKGPEVDIRGPQVD 3005 + P + + P IP + + P + + IS K + P + P + Sbjct: 668 TTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIP 727 Query: 3006 IDVPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLP-----KADLDVSGPKVDI 3060 + + + P + P + K P E P P K + P + Sbjct: 728 TEKSTISPEKPTTPTEKPTIPTEK---PTISPEKPTTPTEKPTISPEKLTIPTEKPTIPT 784 Query: 3061 DVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDM 3120 + P + E P + P E I K S+P ++ P +LP E Sbjct: 785 EKPTIPTEKPTISTEEPTTPTEETTISTEKPSIP-----MEKP--------TLPTEETTT 831 Query: 3121 KVPDVDIKGPKVDI--NAPDVDVQGPDWHLKMPKIKMPKISMPGFKGEGP---------E 3169 V + I K+ I P + + P + P I K+++P K P E Sbjct: 832 SVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEE 891 Query: 3170 VDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP 3222 ++ K + P + + P ++ E P + P E I K+++P Sbjct: 892 TTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIP 944 Score = 59.3 bits (142), Expect = 1e-07 Identities = 79/433 (18%), Positives = 145/433 (33%), Gaps = 58/433 (13%) Query: 771 VNLPKADVDISGPKIDVTAPDVSIEEPEGKLKGPKFKMPEMNIKVPKISMPDVDLHLKGP 830 ++ K V I P + P V E+P + P + I K +MP Sbjct: 565 ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPS-------- 616 Query: 831 NVKGEYDVTMPKVESEIKVPDVELKSAKMDIDVPDVEVQGPDWHLKMPKMKMPKFSMPGF 890 + P + + + + P + + P + P + K ++P Sbjct: 617 -----------------EKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTE 659 Query: 891 KAEGPEVDVNLPKADVDISGPKVGVEVPDVNIEGPEGKLKGPKFKMPE--MNIKAPKISM 948 + P + + P + E P + E P + P M E ++ + P IS Sbjct: 660 EPTTPTEETT-----TSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISP 714 Query: 949 PDVDLHMKGPKVKGEYDMTVP-KLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKFS 1007 + + P + E P K + P + P + + P + P I K + Sbjct: 715 EKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLT 774 Query: 1008 MPSLKGEGPEFDVNLSKANVDISAPKVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKM 1067 +P+ K + P + T P +S E P + + K Sbjct: 775 IPT------------EKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKP 822 Query: 1068 SLPDVDLDLKGPKMKGNVDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIP 1127 +LP + + IS K+ M+ P + P + + P + + L IP Sbjct: 823 TLPTEETTTSVEE----TTISTEKLTIPMEKPTISTEKPTIPTEKPTISPE----KLTIP 874 Query: 1128 KMKMPKFSMPSLKGEGP--EVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKM 1185 K+ ++P+ K P E ++ K + P + E P +S E P + P Sbjct: 875 TEKL---TIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPT 931 Query: 1186 PEMHFKTPKISMP 1198 E T K+++P Sbjct: 932 EETTISTEKLTIP 944 Score = 59.3 bits (142), Expect = 1e-07 Identities = 82/441 (18%), Positives = 149/441 (33%), Gaps = 35/441 (7%) Query: 1481 KAPDVDIKGPKVDINAPDVEVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDMNLP----- 1535 K P V I+ P V P V P + P + K ++P K P +P Sbjct: 568 KKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPT 627 Query: 1536 -----------KADLGVSGPKVDIDVPDVNLEAPEGKLKGPKFKMPSMNIQTHKISMPDV 1584 K + P + + P V E P + M I T K S+P Sbjct: 628 ILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTE 687 Query: 1585 GLNLKAPKLKTDVDVSLPKVEGDLKGPE---IDVKAPKMDVNVGDIDIEGPEGKLKGPKF 1641 ++ K ++ ++ E PE I + P + I E P + P Sbjct: 688 KPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTI 747 Query: 1642 KMPEMHFKAPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVPDVDIKGPKVDIDAPDV 1701 + K + P + K + + K + P + + P + + P Sbjct: 748 PTEKPTISPEKPTTPTEKPTISPEK----LTIPTEKPTIPTEKPTIPTEKPTISTEEPTT 803 Query: 1702 EVHDPDWHLKMPKMKMPKFSMPGFK--AEGPEVDVNLPKADIDVSGPSVDTDAPDLDIEG 1759 + + P + M K ++P + E ++ K I + P++ T+ P + E Sbjct: 804 PTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEK 863 Query: 1760 PEGKLKGSKFKMPKLNIKAPKVSMPDVDLNLKGPKLKGEIDASVPELEGDLRGPQVDVKG 1819 P + KL I K ++P + + KL I P + + P + + Sbjct: 864 PTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKL--TIPTEKPTISPE--KPTISTEK 919 Query: 1820 PFVEAEVPDVDLECPDAKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGD-ADVSVP 1878 P + E P + E + + K +P + P IS + + + P + + + Sbjct: 920 PTIPTEKPTIPTE--ETTISTEKLTIPT---EKPTISPEKLTIPTEKPTISTEKPTIPTE 974 Query: 1879 KLEGDLTGPSVGVEVPDVELE 1899 KL P++ E P + E Sbjct: 975 KLTIPTEKPTIPTEKPTIPTE 995 Score = 58.9 bits (141), Expect = 1e-07 Identities = 80/434 (18%), Positives = 149/434 (34%), Gaps = 35/434 (8%) Query: 1954 PSVGVEVPDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVDLHLKG-----PKVKGDMD 2008 P+V +E P V E P + P + T K ++P ++ P K + Sbjct: 570 PTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTIL 629 Query: 2009 VSVPKVEGEMKV-----PDVDIKGPKMDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKA 2063 P + E P + + P + + P ++ P + K S+P K Sbjct: 630 TEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKP 689 Query: 2064 EGPEVDVNLPKADVVVSG--PKVDVEVPDVSLEGPEGKLKGPKLKMPEMHFKAPKISMPD 2121 P + + ++S P + E P + E P + + + K ++P Sbjct: 690 SIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPT 749 Query: 2122 VDLHLKGPKVKGDVD---VSLPKLEGDLTGPSVDVEVPDVELECPDAKLKGPKFKMPEMH 2178 + K + +S KL P++ E P + E P + P E Sbjct: 750 EKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETT 809 Query: 2179 FKTPKISMPDVNLNLKGPKVKGDMD---VSVPKVEGEMKVPDVDIRGPKVDIDAPDVDVH 2235 T K S+P L + ++ +S K+ M+ P + P + + P + Sbjct: 810 ISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPE 869 Query: 2236 GPDWHLKMPKMKMP--KFSMPGFKGEGP--EVDVNLPKADVDVSGPKVDVEVPDVSLEGP 2291 K+ +P K ++P K P E ++ K + P + E P +S E P Sbjct: 870 ---------KLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKP 920 Query: 2292 EGKLKGPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVDVSAPKLEGELKGPELDVKGP 2351 + P E T K+++P + K+ + P + E P + + Sbjct: 921 TIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKL--TIPTEKPTISTE--KPTIPTEKL 976 Query: 2352 KLDADMPEVAVEGP 2365 + + P + E P Sbjct: 977 TIPTEKPTIPTEKP 990 Score = 58.5 bits (140), Expect = 2e-07 Identities = 77/388 (19%), Positives = 135/388 (34%), Gaps = 22/388 (5%) Query: 1084 NVDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLK--- 1140 N IS K ++ P V P V + P + + S + P + K +MPS K Sbjct: 562 NPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTI 621 Query: 1141 -GEGPEVDVNLP-----KADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKMPEMHFKTPK 1194 E P + P K + P + E P V E P + M E T K Sbjct: 622 PSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEK 681 Query: 1195 ISMPDVDLHLKGPKVKGDVD---VSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWH 1251 S+P + K ++ +S K + P + + P + + + + P Sbjct: 682 PSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTP 741 Query: 1252 LKMPKM--KMPKFSMPGFKGEGREVDVNLPKADIDVSGPKVDVEVPDVSLEGPEGKLKGP 1309 + P + + P S + ++ K I P + E P + E P + P Sbjct: 742 TEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEP 801 Query: 1310 KFKMPEMHFKAPKISMPDVDLNLKGPKL-KGDVDVSLPEVEGEMKVPDVDIKGPKVDISA 1368 E K S+P ++ P L + S+ E + + ++ P + Sbjct: 802 TTPTEETTISTEKPSIP-----MEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEK 856 Query: 1369 PDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGP--EVDVKLPKADVDVSGPKMDAEVPDVN 1426 P + P + + K ++P K P E + K + P + E P ++ Sbjct: 857 PTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTIS 916 Query: 1427 IEGPDAKLKGPKFKMPEMSIKPQKISIP 1454 E P + P E +I +K++IP Sbjct: 917 TEKPTIPTEKPTIPTEETTISTEKLTIP 944 Score = 58.5 bits (140), Expect = 2e-07 Identities = 78/458 (17%), Positives = 159/458 (34%), Gaps = 53/458 (11%) Query: 850 PDVELKSAKMDIDVPDVEVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLP--KADVD 907 P + K + I+ P V + P + P + K ++ K P N+P K + Sbjct: 563 PTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIP 622 Query: 908 ISGPKVGVEVPDVNIEGPEGKLKGPKF--KMPEMNIKAPKISMPDVDLHMKGPKVKGEYD 965 P + E P + E P + P + P + + P + M+ P + E Sbjct: 623 SEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTE-- 680 Query: 966 MTVPKLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGP--EFDVNLS 1023 K + P + P + M+ + + P I K ++P+ K P + ++ Sbjct: 681 ----KPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPE 736 Query: 1024 KANVDISAPKVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKGPKMKG 1083 K P + T P +S E P + P ++ K ++P Sbjct: 737 KPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIP------------- 783 Query: 1084 NVDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLKGEG 1143 + P + P + + P + S + P + M K ++P+ Sbjct: 784 ------------TEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPT----- 826 Query: 1144 PEVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMPDVDLH 1203 E ++ + + + +E P +S E P + P ++ T K+++P Sbjct: 827 EETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIP----- 881 Query: 1204 LKGPKVK-GDVDVSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMPKF 1262 + P + + +S K+ + P + + P + + P + + P + + K Sbjct: 882 TEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKL 941 Query: 1263 SMPGFKGEGREVDVNLPKADIDVSGPKVDVEVPDVSLE 1300 ++P K ++ K I P + E P + E Sbjct: 942 TIPTEK-----PTISPEKLTIPTEKPTISTEKPTIPTE 974 Score = 58.2 bits (139), Expect = 2e-07 Identities = 78/393 (19%), Positives = 131/393 (33%), Gaps = 51/393 (12%) Query: 4031 KAPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVNLP----- 4085 K P V I+ P V + P V P + P + K ++P K P +P Sbjct: 568 KKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPT 627 Query: 4086 ----KADIDVSGPKVDIDTPDIDIHGPEGKLKGP---------KFKMPDLHLKAPKISMP 4132 K I P + + P I P + P + P + + P I Sbjct: 628 ILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTE 687 Query: 4133 EVDLNLKGPKMK-GDVDVSLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHLKMPKV 4191 + + + P + + +S K + P + + P + + + + P + P + Sbjct: 688 KPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTI 747 Query: 4192 KMPKFSMPGFKGEGPDVDVNLP-----KADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFK 4246 K P E P P K + P + + P + E P + P Sbjct: 748 PTEK---PTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTP 804 Query: 4247 MPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDI--DAPD 4304 E I K S+P ++ P +LP E E I K+ I + P Sbjct: 805 TEETTISTEKPSIP-----MEKP--------TLPTEETTTSVEETTISTEKLTIPMEKPT 851 Query: 4305 VDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVTLPKADIEISGPKVDI---------D 4355 + P + P + K ++P K P T+P + IS K+ I + Sbjct: 852 ISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPE 911 Query: 4356 APDVSIEGPDAKLKGPKFKMPEMNIKAPKISMP 4388 P +S E P + P E I K+++P Sbjct: 912 KPTISTEKPTIPTEKPTIPTEETTISTEKLTIP 944 Score = 57.8 bits (138), Expect = 3e-07 Identities = 82/418 (19%), Positives = 137/418 (32%), Gaps = 29/418 (6%) Query: 4613 ISLPKVEGDLKGPEVDIRDPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFK----GE 4668 IS K ++ P V P V + P + + P + P + K +MP K E Sbjct: 565 ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSE 624 Query: 4669 GPDVDVNLP-----KADIDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMSIKAPKISM 4723 P + P K I P + + P V E P + M E I K S+ Sbjct: 625 KPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSI 684 Query: 4724 PDIDLNLKGPKVKGDVDVTLPKVEGDLKGPE---ADIKGPKVDINTPDVDVHGPDWHLKM 4780 P ++ K ++ T+ E PE + P + + P + Sbjct: 685 PTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEK 744 Query: 4781 PKVKMPKFSMPGFKGEGPDVDVSLP-----KADIDVSGPKVDVDIPDVNIEGPDAKLKGP 4835 P + K P E P P K I P + + P + E P + P Sbjct: 745 PTIPTEK---PTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEP 801 Query: 4836 KFKMPEINIKAPKISIPDVDLDLKGPKV-KGDFDVSVPKVEGTLKGPEVDLKGPRLDFEG 4894 E I K SIP ++ P + + SV + + + + ++ P + E Sbjct: 802 TTPTEETTISTEKPSIP-----MEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEK 856 Query: 4895 PDAKLSGPSLKMPSLEISAPKVTAPDVDLHLKAPKIGFSGPKLEGGEVDLKGPKVEAPSL 4954 P P++ L I K+T P + + S KL + + P + Sbjct: 857 PTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKL---TIPTEKPTISPEKP 913 Query: 4955 DVHMDSPDINIEGPDVKIPKFKKPKFGFGAKSPKADIKSPSLDVTVPEAELNLETPEI 5012 + + P I E P + + + K I L + + ++ E P I Sbjct: 914 TISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTI 971 Score = 57.4 bits (137), Expect = 4e-07 Identities = 84/494 (17%), Positives = 168/494 (34%), Gaps = 49/494 (9%) Query: 2734 GDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKIKMPKISMPGFKGEGPDVDVNLPKA 2793 G + P + K P V I+ P V P + P I K ++ K P N+P Sbjct: 558 GLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPS- 616 Query: 2794 DIDVSGPKVDVECPDVNIEGPEGKWKSPKFKMPEMHFKTPKISMPDIDLNLTGPKIKGDV 2853 P + E P + E P + P + T K ++P + T P + Sbjct: 617 ----EKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEE--PTTPTEETTT 670 Query: 2854 DVTGPKVEGDLKGPEVDLKGPKVDIDVPDVNVQGPDWHLKMPKMKMPKFSMPGFKAEGPE 2913 + P + + P + + P + + P ++++ + P + K ++P E P Sbjct: 671 SMEEPVI--PTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIP---TEKPT 725 Query: 2914 VDVNLPKADVDVSGPKVDVEGPDVNIEGPEGKLKGPKFKMPEMNIKAPKIPMPDFDLHLK 2973 + K+ + P E P + E P + P + I K+ +P Sbjct: 726 IPTE--KSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIP------- 776 Query: 2974 GPKVKGDVDISLPKVEGDLKGPEVDIRGPQVDIDVPDVGVQGPDWHLKMPKVKMPKFSMP 3033 + P + P + + P + + P + + K S+P Sbjct: 777 ------------------TEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIP 818 Query: 3034 GFKGEGPDVDVNLPKADLDVSGPKVDI--DVPDVNIEGPEGKLKGPKFKMPEMNIKAPKI 3091 K P + + +S K+ I + P ++ E P + P ++ I K+ Sbjct: 819 MEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKL 878 Query: 3092 SMPDIDLNLKGPKVK-GDMDVSLPKVEGDMKVPDVDIKGPKVDINAPDVDVQGPDWHLKM 3150 ++P + P + + +S K+ + P + + P + P + + P + Sbjct: 879 TIP-----TEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEE 933 Query: 3151 PKIKMPKISMPGFKGEGPEVDVNLP--KADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFK 3208 I K+++P K + +P K + P + + + E P + P Sbjct: 934 TTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIP 993 Query: 3209 MPEMNIKAPKISMP 3222 ++ P P Sbjct: 994 TEKLTALRPPHPSP 1007 Score = 57.0 bits (136), Expect = 5e-07 Identities = 74/408 (18%), Positives = 147/408 (36%), Gaps = 35/408 (8%) Query: 4620 GDLKGPEVDIRDPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLP-- 4677 G + P + + P V I+ P V + P + P + K ++ K P N+P Sbjct: 558 GLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSE 617 Query: 4678 KADIDVSGPKVDVDVPDVNIEGPDAKLKGPKF--KMPEMSIKAPKISMPDIDLNLKGPKV 4735 K I P + + P + E P + P + P + + P + +++ P + Sbjct: 618 KPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVI 677 Query: 4736 KGDVDVTLPKVEGDLKGPEADIKGPKVDINTPDVDVHGPDWHLKMPKVKMPKFSMPGFKG 4795 + K + P + P + + + P + P + K ++P K Sbjct: 678 PTE------KPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKS 731 Query: 4796 EGPDVDVSLPKADIDVSGPKVDVDIPDVNIEGPDAKLKGPKFKMPEINIKAPKISIP--D 4853 +S K P + + P ++ E P + P ++ I K +IP Sbjct: 732 -----TISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEK 786 Query: 4854 VDLDLKGPKVKGDFDVSVPKVEGTLKGPEVDLKGPRLDFEGPDAKLSGPSLKMPSLEISA 4913 + + P + + + + P E T + + P + E P + + IS Sbjct: 787 PTIPTEKPTISTE-EPTTPTEETT-----ISTEKPSIPMEKPTLPTEETTTSVEETTIST 840 Query: 4914 PKVTAPDVDLHLKAPKIGFSGPKLEGGEVDLKGPKVEAPS--LDVHMDSPDINIEGPDVK 4971 K+T P ++ P I P + + + K+ P+ L + + P I IE + Sbjct: 841 EKLTIP-----MEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTIS 895 Query: 4972 IPKFKKP--KFGFGAKSPKADIKSPSLDV---TVPEAELNLETPEISV 5014 K P K + P + P++ T+P E + T ++++ Sbjct: 896 TEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTI 943 Score = 57.0 bits (136), Expect = 5e-07 Identities = 74/400 (18%), Positives = 137/400 (34%), Gaps = 39/400 (9%) Query: 3624 VTLPKADIDISGPNVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLNLKGP 3683 ++ K + I P+V + P V E P + P + I + K +MP + P Sbjct: 565 ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTI--P 622 Query: 3684 KMKGDVVVSLPKVEGDLKGPEVDIKGPKVDIDTPDINIEGSEGKFKGPKFKIPEMHLKAP 3743 K ++ P + + P + + P + + P + E + + E + Sbjct: 623 SEKPTILTEKPTIPSE--KPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTE 680 Query: 3744 KISMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPE---VDIKGPKVDINAPDVDVQGPDW 3800 K S+P ++ K ++ ++ E PE + + P + + + P Sbjct: 681 KPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTT 740 Query: 3801 HLKMPKVKMPKFSMPGFKGEGPDVDVNLP-----KADLDVSGPKVDIDVPDVNIEGPEGK 3855 + P + K P E P P K + P + + P + E P Sbjct: 741 PTEKPTIPTEK---PTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTIS 797 Query: 3856 LKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDMDVSLPKVEGDMQVPDLDIKGPKVD 3915 + P E I K S+P ++ P +LP E V + I K+ Sbjct: 798 TEEPTTPTEETTISTEKPSIP-----MEKP--------TLPTEETTTSVEETTISTEKLT 844 Query: 3916 I--NAPDVDVRGPDWHLKMPKIKMPKISMPGFKGEGP---------EVDVNLPKADLDVS 3964 I P + P + P I K+++P K P E ++ K + Sbjct: 845 IPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTE 904 Query: 3965 GPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP 4004 P + + P ++ E P + P E I K+++P Sbjct: 905 KPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIP 944 Score = 56.2 bits (134), Expect = 9e-07 Identities = 95/516 (18%), Positives = 176/516 (34%), Gaps = 74/516 (14%) Query: 1665 PKVKGDMDVSVPKVEGEMKVPDVDIKGPKVDIDAPDVEVHDPDWHLKMPKMKMPKFSMPG 1724 P V + G + P + K P V I+ P V P +PK K P Sbjct: 543 PPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKP----TVPKEK------PT 592 Query: 1725 FKAEGPEVDVNLPKADIDVSGPSVDTDAPDLDIEGPEGKLKGSKFKMPKLNIKAPKVSMP 1784 E P + P I P++ ++ P + E P + P + + P + Sbjct: 593 IPTEKPTISTEKP--TIPSEKPNMPSEKPTIPSEKPT-----ILTEKPTIPSEKPTIPSE 645 Query: 1785 DVDLNLKGPKLKGEIDASVPELEGDLRGPQVDVKGPFVEAEVPDVDLECPDAKLKGPKFK 1844 ++ + P + E + + P E ++ P + E P + E P + P Sbjct: 646 KPTISTEKPTVPTE-EPTTPTEE-----TTTSMEEPVIPTEKPSIPTEKPSIPTEKPTIS 699 Query: 1845 MPE--MHFKAPKISMPDVDLHLKGPKVKGD-ADVSVPKLEGDLTGPSVGVEVPDVELECP 1901 M E + + P IS + + P + + + +S K P++ E P + E P Sbjct: 700 MEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKP 759 Query: 1902 DAKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDVDVSVPKLEGDLTGPSVGVEVP 1961 + P + K ++P + P K + P + T ++ E P Sbjct: 760 TTPTEKPTISPEKLTIPTEKPTIPTEKPTI--PTEKPTISTEEPTTPTEET--TISTEKP 815 Query: 1962 DVELECPDAKLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKVP 2021 + +E P + + E T K+++P M+ P Sbjct: 816 SIPMEKPTLPTEETTTSVEETTISTEKLTIP-------------------------MEKP 850 Query: 2022 DVDIKGPKMDIDAPDVDVHGPDWHLKMPKMKMP--KFSMPGFKAEGP--EVDVNLPKADV 2077 + + P + + P + K+ +P K ++P K P E ++ K + Sbjct: 851 TISTEKPTIPTEKPTISPE---------KLTIPTEKLTIPTEKPTIPIEETTISTEKLTI 901 Query: 2078 VVSGPKVDVEVPDVSLEGPEGKLKGPKLKMPEMHFKAPKISMPDVDLHLKGPKV-----K 2132 P + E P +S E P + P + E K+++P + K+ K Sbjct: 902 PTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEK 961 Query: 2133 GDVDVSLPKLEGD-LTGPSVDVEVPDVELECPDAKL 2167 + P + + LT P+ +P + P KL Sbjct: 962 PTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKL 997 Score = 55.8 bits (133), Expect = 1e-06 Identities = 79/439 (17%), Positives = 144/439 (32%), Gaps = 63/439 (14%) Query: 2532 VNLPKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPKISMPDFDLHLKGP 2591 ++ K V I P V E P V E P + P + + I + K +MP Sbjct: 565 ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPS-------- 616 Query: 2592 KVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKMPKVKMPKFSMPGF 2651 + P + + P + P + + P + P + K ++P Sbjct: 617 -----------------EKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTE 659 Query: 2652 KGEGPDGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKLKGPKFKMPE--MNIKAPKISM 2709 + P + + P + E P + E P + P M E ++ + P IS Sbjct: 660 EPTTP-----TEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISP 714 Query: 2710 PDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKI 2769 + + P + + P + P + P + + P + P + P I Sbjct: 715 EKPTIPTEKPTIPTEKSTISP------EKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTI 768 Query: 2770 KMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGPEGKWKSPKFKMPEMH 2829 K+++P K P + E P + E P + P E Sbjct: 769 SPEKLTIPTEK-------------------PTIPTEKPTIPTEKPTISTEEPTTPTEETT 809 Query: 2830 FKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPEVDLKGPKVDIDVPDVNVQGPD 2889 T K S+P L + V+ T E + ++ P + + P + + P Sbjct: 810 ISTEKPSIPMEKPTLPTEETTTSVEETTISTE----KLTIPMEKPTISTEKPTIPTEKPT 865 Query: 2890 WHLKMPKMKMPKFSMPGFKAEGP--EVDVNLPKADVDVSGPKVDVEGPDVNIEGPEGKLK 2947 + + K ++P K P E ++ K + P + E P ++ E P + Sbjct: 866 ISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTE 925 Query: 2948 GPKFKMPEMNIKAPKIPMP 2966 P E I K+ +P Sbjct: 926 KPTIPTEETTISTEKLTIP 944 Score = 55.5 bits (132), Expect = 2e-06 Identities = 87/434 (20%), Positives = 155/434 (35%), Gaps = 28/434 (6%) Query: 4149 VSLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHLKMPKVKMPKFSMPGFK----GE 4204 +S K ++ P V + P V + P + + P + P + K +MP K E Sbjct: 565 ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSE 624 Query: 4205 GPDVDVNLP-----KADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISM 4259 P + P K + P + + P V E P + M E I K S+ Sbjct: 625 KPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSI 684 Query: 4260 PDFDLHLKGPKVKGDVDVSLPKVEGDLKGPE---VDIKGPKVDIDAPDVDVHGPDWHLKM 4316 P + K ++ ++ E PE + + P + + + P + Sbjct: 685 PTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEK 744 Query: 4317 PKVKMPKFSMPGFKGEGPDVDVTL--PKADIEISGPKVDIDAPDVSIEGPDAKLKGPKFK 4374 P + K ++ K P T+ K I P + + P + E P + P Sbjct: 745 PTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTP 804 Query: 4375 MPEMNIKAPKISMPDIDFNLKGPKVKGDVD---VSLPKVEGDLKGPEIDIKGPSLDIDTP 4431 E I K S+P L + V+ +S K+ ++ P I + P++ + P Sbjct: 805 TEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKP 864 Query: 4432 DVNIEG---PEGKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGD-VDVSLPKVESD 4487 ++ E P KL P K P + I+ IS + + P + + +S K Sbjct: 865 TISPEKLTIPTEKLTIPTEK-PTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIP 923 Query: 4488 LKGPEVDIEGPEGKLKGPKFKMPDVHFKSPQISMSDIDLNLKGPKIKGDM-DISVPKLEG 4546 + P + E E + K +P + P IS + + + P I + I KL Sbjct: 924 TEKPTIPTE--ETTISTEKLTIPT---EKPTISPEKLTIPTEKPTISTEKPTIPTEKLTI 978 Query: 4547 DLKGPKVDVKGPKV 4560 + P + + P + Sbjct: 979 PTEKPTIPTEKPTI 992 Score = 55.1 bits (131), Expect = 2e-06 Identities = 75/396 (18%), Positives = 131/396 (33%), Gaps = 58/396 (14%) Query: 717 VTVPKLEGELKGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSVPGFKAEGPEVDVNLP-- 774 ++ K ++ P V + P V P + P + K ++P K P +P Sbjct: 565 ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSE 624 Query: 775 --------------KADVDISGPKIDVTAPDVSIEEPEGKLKGPKFKM------------ 808 K + P I P V EEP + M Sbjct: 625 KPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSI 684 Query: 809 ----PEMNIKVPKISMPDVDLHLKGPNVKGEYDVTMPKVESEIKVPDVELKSAKMDIDVP 864 P + + P ISM + + + P + E P + +E P + + + + + P Sbjct: 685 PTEKPSIPTEKPTISMEETIISTEKPTISPE----KPTIPTE--KPTIPTEKSTISPEKP 738 Query: 865 DVEVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVGVEVPDVNIEG 924 + P + P + K + P E P + K + P + E P + E Sbjct: 739 TTPTEKPTIPTEKPTISPEKPTTP---TEKPTISPE--KLTIPTEKPTIPTEKPTIPTEK 793 Query: 925 PEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGPKVKGEYDMT--------VPKLEGDLK 976 P + P E I K S+P M+ P + E T KL ++ Sbjct: 794 PTISTEEPTTPTEETTISTEKPSIP-----MEKPTLPTEETTTSVEETTISTEKLTIPME 848 Query: 977 GPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGP--EFDVNLSKANVDISAPKV 1034 P + P + + P + + I K ++P+ K P E ++ K + P + Sbjct: 849 KPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTI 908 Query: 1035 DTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLP 1070 P +S E P + P E K+++P Sbjct: 909 SPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIP 944 Score = 54.3 bits (129), Expect = 4e-06 Identities = 85/446 (19%), Positives = 147/446 (32%), Gaps = 62/446 (13%) Query: 899 VNLPKADVDISGPKVGVEVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGP 958 ++ K V I P V E P V E P + P + I + K +MP + P Sbjct: 565 ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPS-----EKP 619 Query: 959 KVKGEYDMTVPKLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGPEF 1018 + E P + P + + P + P I K ++P+ + P Sbjct: 620 TIPSE-------------KPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTE 666 Query: 1019 DVNLSKANVDISAPKVDTNAPDLSLEGPEGKLKGPKFKMPEMHFRAPKMSLPDVDLDLKG 1078 + S + P + T P + E P + P M E K ++ + Sbjct: 667 ETTTS-----MEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTI-- 719 Query: 1079 PKMKGNVDISAPKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPS 1138 P K + I E P P + + P + + + P + K ++P+ Sbjct: 720 PTEKPTIPTEKSTISPEK--PTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPT 777 Query: 1139 LKGEGPEVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKMPEMHFKTPKISMP 1198 K P + E P + E P + P E T K S+P Sbjct: 778 EK-------------------PTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIP 818 Query: 1199 DVDLHLKGPKVKGDVD---VSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMP 1255 L + V+ +S K+ M+ P + + P + + P + + Sbjct: 819 MEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPE--------- 869 Query: 1256 KMKMP--KFSMPGFKG--EGREVDVNLPKADIDVSGPKVDVEVPDVSLEGPEGKLKGPKF 1311 K+ +P K ++P K E ++ K I P + E P +S E P + P Sbjct: 870 KLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTI 929 Query: 1312 KMPEMHFKAPKISMPDVDLNLKGPKL 1337 E K+++P + KL Sbjct: 930 PTEETTISTEKLTIPTEKPTISPEKL 955 Score = 53.5 bits (127), Expect = 6e-06 Identities = 78/438 (17%), Positives = 143/438 (32%), Gaps = 67/438 (15%) Query: 2149 PSVDVEVPDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMDVSVPK 2208 P+V +E P V E P + P + T K ++P N+ K Sbjct: 570 PTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEK----------- 618 Query: 2209 VEGEMKVPDVDIRGPKVDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKGEGPEVDVNLP 2268 P + P + + P + P + P + K ++P + P + Sbjct: 619 -------PTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETT-- 669 Query: 2269 KADVDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKT--PKISMPDVDFNLKGPKI 2326 + P + E P + E P + P M E T P IS + P I Sbjct: 670 ---TSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTI 726 Query: 2327 KGDVDVSAPKLEGELKGPELDVKGPKLDADMPEVAVEGPNGKWKTPKFKMPDMHFKAPKI 2386 + +P + P + P + + P ++ E P TP K P I Sbjct: 727 PTEKSTISP------EKPTTPTEKPTIPTEKPTISPEKPT----TPTEK--------PTI 768 Query: 2387 SMPDLDLHLKSPKAKGEVDVDVPKLEGDLKGPHVDVSGPDIDIEGPEGKLKGPKF--KMP 2444 S L + + P E P + P I E P + + P Sbjct: 769 SPEKLTIPTEKPTIPTE-------------KPTIPTEKPTISTEEPTTPTEETTISTEKP 815 Query: 2445 DMHFKAPNISMPDVDLNLKGPKIKGDVDVSVPEVEGKLEVPDMNIRGPKVDVNAPDVQAP 2504 + + P + + +++ + +S ++ +E P ++ P + P + Sbjct: 816 SIPMEKPTLPTEETTTSVE------ETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPE 869 Query: 2505 DWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDIEGPDVNIEGPEGKLKG 2564 + K+ +P P E E ++ K + P + E P ++ E P + Sbjct: 870 KLTIPTEKLTIPT-EKPTIPIE--ETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEK 926 Query: 2565 PKLKMPEMNIKAPKISMP 2582 P + E I K+++P Sbjct: 927 PTIPTEETTISTEKLTIP 944 Score = 52.4 bits (124), Expect = 1e-05 Identities = 72/414 (17%), Positives = 140/414 (33%), Gaps = 57/414 (13%) Query: 1227 PDVEIKGPKMDIDAPDVEVQGPDWHLKMPKMKMPKFSMPGFKGEGREVDVNLPKADIDVS 1286 P + K P + I+ P V + P + P + K + ++ K I Sbjct: 563 PTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPT------------ISTEKPTIPSE 610 Query: 1287 GPKVDVEVPDVSLEGPEGKLKGPKF--KMPEMHFKAPKISMPDVDLNLKGPKLKGDVDVS 1344 P + E P + E P + P + P + + P IS + + P + Sbjct: 611 KPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTE---- 666 Query: 1345 LPEVEGEMKVPDVDIKGPKVDISAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDV 1404 E M+ P + + P + P + P ++ + K P E P + Sbjct: 667 --ETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEK---PTISPEKPTIPT 721 Query: 1405 KLP-----KADVDVSGPKMDAEVPDVNIEGPDAKLKGPKFKMPEMSIKPQKISIPDVGLH 1459 + P K+ + P E P + E P + P + +I P+K++IP Sbjct: 722 EKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIP----- 776 Query: 1460 LKGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKVDINAPDVEVHGPDWHLKMPKVKMPKFS 1519 T+P + P + + P + P + P + M K + Sbjct: 777 --------TEKPTIP-----TEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPT 823 Query: 1520 MPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPDVNLEAPEGKLKGPKFKMPSMNIQTHKI 1579 +P E ++ + + + ++ P ++ E P + P + I T K+ Sbjct: 824 LP-----TEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKL 878 Query: 1580 SMPDVGLNLKAPKLK-TDVDVSLPKVEGDLKGPEIDVKAPKMDVNVGDIDIEGP 1632 ++P + P + + +S K+ + P I + P + I E P Sbjct: 879 TIP-----TEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKP 927 Score = 52.4 bits (124), Expect = 1e-05 Identities = 89/435 (20%), Positives = 148/435 (34%), Gaps = 39/435 (8%) Query: 2070 VNLPKADVVVSGPKVDVEVPDVSLEGPEGKLKGPKLKMPEMHFKAPKISMPDVDLHLKGP 2129 ++ K V + P V E P V E P + P + + + K +MP + P Sbjct: 565 ISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTI--P 622 Query: 2130 KVKGDVDVSLPKLEGD-----LTGPSVDVEVPDVELECPDAKLKGPKFKMPEMHFKTPKI 2184 K + P + + P++ E P V E P + M E T K Sbjct: 623 SEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKP 682 Query: 2185 SMPDVNLNLKGPKVKGDMD---VSVPKVEGEMKVPDVDIRGPKVDIDAPDVDVHGPDWHL 2241 S+P ++ K M+ +S K + P + P + + + P Sbjct: 683 SIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPT 742 Query: 2242 KMPKMKMPKFSMPGFKGEGPEVDVNLP-----KADVDVSGPKVDVEVPDVSLEGPEGKLK 2296 + P + K P E P P K + P + E P + E P + Sbjct: 743 EKPTIPTEK---PTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTE 799 Query: 2297 GPKFKMPEMHFKTPKISMPDVDFNLKGPKIKGDVD---VSAPKLEGELKGPELDVKGPKL 2353 P E T K S+P L + V+ +S KL ++ P + + P + Sbjct: 800 EPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTI 859 Query: 2354 DADMPEVAVEG---PNGKWKTPKFKMPDMHFKAPKISMPDLDLHLKSPKAKGEVDVDVPK 2410 + P ++ E P K P K P + + IS L + P K + + P Sbjct: 860 PTEKPTISPEKLTIPTEKLTIPTEK-PTIPIEETTISTEKLTI----PTEKPTISPEKPT 914 Query: 2411 LEGDLKGPHVDVSGPDIDIEGPEGKLKGPKFKMPDMHFKAPNISMPDVDLNLKGPKIKGD 2470 + + P + P I E E + K +P + P IS + + + P I + Sbjct: 915 I--STEKPTIPTEKPTIPTE--ETTISTEKLTIPT---EKPTISPEKLTIPTEKPTISTE 967 Query: 2471 VDVSVPEVEGKLEVP 2485 E KL +P Sbjct: 968 KPTIPTE---KLTIP 979 Score = 52.0 bits (123), Expect = 2e-05 Identities = 77/493 (15%), Positives = 159/493 (32%), Gaps = 47/493 (9%) Query: 3772 GDLKGPEVDIKGPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKA 3831 G + P + K P V I P V + P + P + K ++ K P N+P Sbjct: 558 GLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPS- 616 Query: 3832 DLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDM 3891 P + + P + E P + P + I K ++P + + M Sbjct: 617 ----EKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSM 672 Query: 3892 DVSLPKVEGDMQVPDLDIKGPKVDINAPDVDVRGPDWHLKMPKIKMPKISMPGFKGEGP- 3950 + + E P + + P + P + + + P I K ++P K P Sbjct: 673 EEPVIPTE----KPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPT 728 Query: 3951 -EVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMPDFDLH 4009 + ++ K P + + P ++ E P + P ++ I K ++P Sbjct: 729 EKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIP----- 783 Query: 4010 LKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVKMPKFS 4069 + P + + P + + P + P + M K + Sbjct: 784 --------------------TEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPT 823 Query: 4070 MPGFKGEGPEVDVNLPKADIDVSGPKVDIDTPDIDIHGPEGKLKGPKFKMPDLHLKAPKI 4129 +P E ++ + I + ++ P I P + P L + K+ Sbjct: 824 LP-----TEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKL 878 Query: 4130 SMPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDVPDVDVQGPDWHLKMP 4189 ++P K + +S K+ + P + + P + + P + + P + Sbjct: 879 TIP----TEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEET 934 Query: 4190 KVKMPKFSMPGFKGEGPDVDVNLP--KADLDVSGPKVDIDVPDVNIEGPDAKLKGPKFKM 4247 + K ++P K + +P K + P + + + E P + P Sbjct: 935 TISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPTIPT 994 Query: 4248 PEMNIKAPKISMP 4260 ++ P P Sbjct: 995 EKLTALRPPHPSP 1007 Score = 51.2 bits (121), Expect = 3e-05 Identities = 94/511 (18%), Positives = 170/511 (33%), Gaps = 58/511 (11%) Query: 3394 VQGKVKGSKFKMPFLSISS---PKVSMPDVELNLKSPKVKGDLDIAGPNLEGDFKGPKVD 3450 +QG S M F+ I+ P +P++ P V G + P + Sbjct: 513 IQGSNTASVVAMGFILINPGTCPVKVLPEL------PPVSPVSSTGPSETTGLTENPTIS 566 Query: 3451 IKAPEVNLNAPDVDVHGPDWNLKMPKMKMPKFSVSGLK------------------AEGP 3492 K P V++ P V P + P + K ++S K +E P Sbjct: 567 TKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKP 626 Query: 3493 DVAVDLP-----KGDINIEGPSMNIEGPDLNVEGPEGGLKGPKFKMPDMNIKAPKISMPD 3547 + + P K I E P+++ E P + E P + M + I K S+P Sbjct: 627 TILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPT 686 Query: 3548 IDLNLKGPKVKGDVDISLPKLEGDLKGPE---VDIKGPKVDINAPDVDVHGPDWHLKMPK 3604 ++ K ++ ++ E PE + + P + + P + P Sbjct: 687 EKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEKPT 746 Query: 3605 VKMPKFSMPGFKGEGPEVDVTL--PKADIDISGPNVDVDVPDVNIEGPDAKLKGPKFKMP 3662 + K ++ K P T+ K I P + + P + E P + P Sbjct: 747 IPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTE 806 Query: 3663 EMNIKAPKISMPDFDLNLKGPKMKGDV---VVSLPKVEGDLKGPEVDIKGPKVDIDTPDI 3719 E I K S+P L + V +S K+ ++ P + + P + + P I Sbjct: 807 ETTISTEKPSIPMEKPTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTI 866 Query: 3720 NIEGSEGKFKGPKFKIPEMHLKAPKISMPDIDLNLKGPKVKGDVDVSLPKMEGDLKGPEV 3779 + E K IP L P P I + + +S K+ + P + Sbjct: 867 SPE---------KLTIPTEKLTIP-TEKPTIPIE--------ETTISTEKLTIPTEKPTI 908 Query: 3780 DIKGPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPK 3839 + P + P + + P + + K ++P K + +P +S K Sbjct: 909 SPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEK 968 Query: 3840 VDIDVPDVNIEGPEGKLKGPKFKMPEMNIKA 3870 I + I + + K +P + A Sbjct: 969 PTIPTEKLTIPTEKPTIPTEKPTIPTEKLTA 999 Score = 46.2 bits (108), Expect = 0.001 Identities = 94/486 (19%), Positives = 178/486 (36%), Gaps = 65/486 (13%) Query: 239 AGHSK-LQVTMPGIKVGGSGVNVNAKGLDLGGRGGVQV------PAVDISSSLGGRAVE- 290 +GH + +Q+ GI+ G + +V A G L G V P V SS G Sbjct: 500 SGHQQPMQLIFKGIQ-GSNTASVVAMGFILINPGTCPVKVLPELPPVSPVSSTGPSETTG 558 Query: 291 -VQGPSLESGDHGKIKFPTMKVPKFGVSTGREGQTPKAGLRVSAPEVSVGHKGGKPGLTI 349 + P++ + K PT+ + K V+T + PK + + ++ + KP + Sbjct: 559 LTENPTIST------KKPTVSIEKPSVTTEKP-TVPKEKPTIPTEKPTISTE--KPTIPS 609 Query: 350 QAPQLEVSVPSANIEGLEGKLKGPQITG--PSLEGDLGLKGAKPQGHIGVDASAP--QIG 405 + P + P+ E + P I P++ + + + + P + Sbjct: 610 EKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETT 669 Query: 406 GSITGPSVEVQAPDIDVQGPGSKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVPGV 465 S+ P + + P I + P P + + + +S K + T+PT + T+P Sbjct: 670 TSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTIPTE 729 Query: 466 SGDVSLPEIATGGLEGKMKGTKVKTPEMIIQKPKISMQDVDLSLGSPKLKGDIKVSAPGV 525 +S PE T T + P + +KP IS + P + + K++ P Sbjct: 730 KSTIS-PEKPT---------TPTEKPTIPTEKPTISPEKPTTPTEKPTISPE-KLTIP-- 776 Query: 526 QGDVKGPQVALKGSRVDIETPNLEGTLTGPRLGSPSGKTGTCRISMSEVDLNVAAPKVKG 585 + P + + + E P + P+ T IS + + + P Sbjct: 777 ---TEKPTIPTEKPTIPTEKPTIS-------TEEPTTPTEETTISTEKPSIPMEKP---- 822 Query: 586 GVDVTLPRVEGKVKVPEVDVRGPK--VDVSAPDVEAHGPEWNLKMPKMKMPTFSTPGAKG 643 TLP E V E + K + + P + P + P + + P K Sbjct: 823 ----TLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKL 878 Query: 644 EGPDVHMTLPKGDISIS---------GPKVNVEAPDVNLEGLGGKLKGPDVKLPDMSVKT 694 P T+P + +IS P ++ E P ++ E + P + + ++ T Sbjct: 879 TIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTIST 938 Query: 695 PKISMP 700 K+++P Sbjct: 939 EKLTIP 944 Score = 45.1 bits (105), Expect = 0.002 Identities = 83/440 (18%), Positives = 145/440 (32%), Gaps = 63/440 (14%) Query: 4903 SLKMPSLEISAPKVTAPDVDLHLKAPKIGFSGPKLEGGEVDLKGPKVEAPSLDVHMDSPD 4962 S K P++ I P VT + + P I P + + + K PS + P Sbjct: 566 STKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPS-----EKPT 620 Query: 4963 INIEGPDVKIPKFKKPKFGFGAKSPKADIKSPSLDV---TVPEAELNLETPEISVGGKGK 5019 I E P + K P ++ P + P++ TVP E T E + + Sbjct: 621 IPSEKPTILTEKPTIP-----SEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEP 675 Query: 5020 KSKFKMPKIHMSGPKIKAKKQGFDLNVPGGEIDASLKAPDVD-----VNIAGPDAALKVD 5074 + P I P I +K + E S + P + + P + Sbjct: 676 VIPTEKPSIPTEKPSIPTEKPTISME----ETIISTEKPTISPEKPTIPTEKPTIPTEKS 731 Query: 5075 VKSPKTKKTMFGKMYFPDVEFDIKSPKFKAEAPLPSPKLEGELQAPDLELSLPAIHVEGL 5134 SP+ T K P E P SP + P P I E L Sbjct: 732 TISPEKPTTPTEK------------PTIPTEKPTISP------EKPTTPTEKPTISPEKL 773 Query: 5135 DIKAKAPKV--KMPDVDISVPKIEGDLKGPKVQANLGAPDINIEGLDAKVKTPSFGISAP 5192 I + P + + P + P I + P E + PS + P Sbjct: 774 TIPTEKPTIPTEKPTIPTEKPTISTE-----------EPTTPTEETTISTEKPSIPMEKP 822 Query: 5193 QVSIPDVNVNLKGPKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGG 5252 + + +++ I + ++ +E P + + P + P S K+ IP K+ Sbjct: 823 TLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIPT 882 Query: 5253 -------AEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGV--DLPSVNLSMPKVSGPDLD 5303 E L P + E P +S + P + + P++ +S L Sbjct: 883 EKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLT 942 Query: 5304 LNLKGPSLKGDLDASVPSMK 5323 + + P++ + ++P+ K Sbjct: 943 IPTEKPTISPE-KLTIPTEK 961 Score = 33.9 bits (76), Expect = 4.9 Identities = 29/152 (19%), Positives = 59/152 (38%), Gaps = 15/152 (9%) Query: 5183 KTPSFGISAPQVSIPDVNVNLKGPKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIG 5242 + P+ P VSI +V + P + + P++ E P + + P + P K Sbjct: 561 ENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPT 620 Query: 5243 IPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDL 5302 IP K + + P++ + P + E P +S + P+V P + Sbjct: 621 IPSEK-----PTILTEKPTIPSE--KPTIPSEKPTIS-----TEKPTVPTEEPTTPTEET 668 Query: 5303 DLNLKGPSL---KGDLDASVPSMKVHAPGLNL 5331 +++ P + K + PS+ P +++ Sbjct: 669 TTSMEEPVIPTEKPSIPTEKPSIPTEKPTISM 700 >gi|169205253 PREDICTED: hypothetical protein [Homo sapiens] Length = 3859 Score = 60.5 bits (145), Expect = 5e-08 Identities = 250/1036 (24%), Positives = 353/1036 (34%), Gaps = 180/1036 (17%) Query: 1090 PKIEGEMQVPDVDIRGPKVDIKAPDVEGQGLDWSLKIPKMKMPKFSMPSLKG-EGPEVDV 1148 P + G+ V V V + PDV + + P P + P+ G P Sbjct: 2918 PDLSGDCPVVPVPPTDDIVVLNPPDV----VFAVVSTPVTDGPVVTDPATDGLMVPVTPA 2973 Query: 1149 NLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFK---MPEMHFKTPKISMPDVD-LHL 1204 N A V +S E PDV++ +G + P +P+ + +S P D L + Sbjct: 2974 NGSVAPVTLS------EYPDVTVTPADGTVVSPTIGGPVVPDPSADSSVVSNPTTDGLIV 3027 Query: 1205 KGPKVKGDVDVSVPKVEGEMKVPDVEIKGPKMDIDAPDVEVQGPDWHLKMP-KMKMPKFS 1263 P + G V V V +G + P + D PDV V D + P F Sbjct: 3028 PNPLLAGPV-VPVTPTDGPL--------APVILADCPDVTVTPADGPVVCAFTTGGPVFP 3078 Query: 1264 MPGFKGEGREVDVNLPKADIDVSGPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKAPKI 1323 P +G + VS P VD D + P KG P P I Sbjct: 3079 DPTAEG-------------LVVSNPTVD----DPVVTNPS--TKGLVSATPADCADVPVI 3119 Query: 1324 --SMPDVDLNLKGPKLKGDVDVSLPEVEGEMKVPDVDIKGPKVDISAPDVDVHGPDWHLK 1381 PDV +NL + VPD V +S PD D+ PD + Sbjct: 3120 PADCPDVLVNLVNDSV----------------VPDFTADWTVVSVSPPD-DLVAPDPPDE 3162 Query: 1382 MPKVKMPKFS---MPGFKGEGPEVDVKLPKADVDVSGPKMDAEVPDVNIEGPDAKLKGPK 1438 +P V +P +P +G V V A V P + PDV + D+ P Sbjct: 3163 VPVVLVPITDGPVVPDLTTDGLVVSVTPAGAPVV---PVFLTDCPDVTVTPADS----PV 3215 Query: 1439 FKMPEMSIKPQKISIPDVGLHLKGPKMKGDYDVTVPKVEGEIKAPDVDIKGPKVDINAPD 1498 P S+ D GL P D V + PD GP APD Sbjct: 3216 VPDPSSDGPVVADSLDDDGLV---PVTPADDSVVPDSPANGLVVPDPTTDGPV----APD 3268 Query: 1499 VEVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPDVNLEAP 1558 V GP +P + P V + L P V + PD L Sbjct: 3269 PSVDGP--------------VVPVTPADAPTVSVTLADC------PDVTVTPPD-GLVVS 3307 Query: 1559 EGKLKGPKFKMPSMNIQTHKISMPDVGLNLKAPKLKTDVDVS---LPKVEGDLKGPEI-D 1614 + K GP S N + D P DV V+ P V + + P + D Sbjct: 3308 DSKRGGPVVTGLSTNDPVITATPADFSDVTVTPADFEDVPVTPANCPDVPVNPESPVVSD 3367 Query: 1615 VKAPKMDVNVGDID----IEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGD 1670 + + V V D +E P+ K P + P + + + + Sbjct: 3368 LAVDFLVVPVVPSDDLVVLEPPD---------------KVPVVPDPISNGLVVSDPITNN 3412 Query: 1671 MDVSVPKVEGEMKVPDVDIKGPKVDI---DAPDVEVHDPDWHLKMPKMKMPKFS-MPGFK 1726 + P V+G + VP GP + D PDV + D + +F +P Sbjct: 3413 TAATDPSVDGSV-VPVSPADGPVAPVTLADCPDVTITPADDSVVSDSKIRAEFEDVPVTI 3471 Query: 1727 AEGPEVDVNLPKADIDVSGPSVDTDAPDLDIEGPEGKLKGSKFKMPKLNIKAPKVSMPDV 1786 A+ P V VN PK+ VS +VD P + I P+ + P+ + P V P Sbjct: 3472 ADCPNVPVN-PKSGPVVSDLAVD--CPVVPIPPPDDLVA------PEPPDEVPVVPDPIT 3522 Query: 1787 D-LNLKGPKLKGEIDASVPELEGDLRGPQVDVKGPFVEAEVPDVDLECPDAKLKGPKFKM 1845 D L + P G + AS P ++G + P V G V V DV + PD P + Sbjct: 3523 DSLVVSDPMTDGPV-ASDPSIDG-IVVPVVSPSGLLVLDSVADVSI-LPDTSADVPVTPV 3579 Query: 1846 PEMHFKAPKISMPDVDLHLKGPKVKGDADVSVPKLEGDLTGPS---VGVEVPDVELECPD 1902 S PD + P + D V + L + P+ VG VPD + PD Sbjct: 3580 TLADGSVVPDSAPDCPVV---PVLPTDGFVVLDLLVDGVVVPNPADVGPVVPDPTTDGPD 3636 Query: 1903 AKLKGPKFKMPDMHFKAPKISMPDVDLHLKGPKVKGDV--DVSVPKLEGDLTGPSVGVEV 1960 + P +PD P + + D GP V V VP GD SV + Sbjct: 3637 SIKDFPL--VPDPWPDCPVVPVTRTD----GPVVLDSSADGVVVPVTPGD---DSVALVT 3687 Query: 1961 PDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVDLHLKGPKVKGDMDVSVPKVEGEMKV 2020 P L PD GP P +S+ D DL + P VK D VP + V Sbjct: 3688 PTDNLVVPDLTTDGPVVPDPSADGPVVLVSLAD-DLLVPNPPVK---DTVVPNSVADNPV 3743 Query: 2021 PDVDIKGPKMDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVVVS 2080 + D P V P+ + EGP V VV++ Sbjct: 3744 ALDPVT------DCPLV-----------PEPSANGLVVTDSLDEGPVVPDPSADDPVVLN 3786 Query: 2081 GPKVDVEVPDVSLEGP 2096 + VPD+S GP Sbjct: 3787 PETNGLVVPDISANGP 3802 Score = 58.9 bits (141), Expect = 1e-07 Identities = 208/880 (23%), Positives = 298/880 (33%), Gaps = 162/880 (18%) Query: 2355 ADMPEVAVEGPNGKWKTPKFKMPDMHFKAPKISMPDLD------------LHLKSPKAKG 2402 AD+P V GP +PD+ P + +P D + +P G Sbjct: 2905 ADVPVNPVNGP---------VVPDLSGDCPVVPVPPTDDIVVLNPPDVVFAVVSTPVTDG 2955 Query: 2403 EVDVDVPKLEGDLKGPHVDVSG----------PDIDIEGPEGKLKGPKFK---MPDMHFK 2449 V D P +G L P +G PD+ + +G + P +PD Sbjct: 2956 PVVTD-PATDG-LMVPVTPANGSVAPVTLSEYPDVTVTPADGTVVSPTIGGPVVPDPSAD 3013 Query: 2450 APNISMPDVD-LNLKGPKIKGDVDVSVPEVEGKL------EVPDMNIR---GPKVDVNA- 2498 + +S P D L + P + G V V V +G L + PD+ + GP V Sbjct: 3014 SSVVSNPTTDGLIVPNPLLAGPV-VPVTPTDGPLAPVILADCPDVTVTPADGPVVCAFTT 3072 Query: 2499 -----PDVQAPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDISGPKVDIEGPDV 2553 PD A + P + P + P K + ADV P + + PDV Sbjct: 3073 GGPVFPDPTAEGLVVSNPTVDDPVVTNPSTKGLVSATPADC--ADV----PVIPADCPDV 3126 Query: 2554 NIEGPEGKLKGPKLKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEV 2613 + + +P+ +S+ D L P +V V L + P++ Sbjct: 3127 LVNLVNDSV------VPDFTADWTVVSVSPPD-DLVAPDPPDEVPVVLVPITDGPVVPDL 3179 Query: 2614 DIKGPKVDINAPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDGDVKLPKADIDVSGPK 2673 G V + V P + P V + P DG V D D P Sbjct: 3180 TTDGLVVSVTPAGAPVV-PVFLTDCPDVTVTPADSPVVPDPSSDGPVVADSLDDDGLVPV 3238 Query: 2674 VDIEGPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDIDLNLKGPKVKGDVDVSLPKVE 2733 + V P+ G +P+ P P +D GP V Sbjct: 3239 TPADDSVV----PDSPANG--LVVPDPTTDGPVAPDPSVD----GPVV------------ 3276 Query: 2734 GDLKGPEVDIKGPKVDI---DAPDVDVHGPDWHLKMPKIKMPKISMPGFKGEGPDV---- 2786 P P V + D PDV V PD L + K + G P + Sbjct: 3277 -----PVTPADAPTVSVTLADCPDVTVTPPDG-LVVSDSKRGGPVVTGLSTNDPVITATP 3330 Query: 2787 ----DVNLPKADIDVSGPKVDVECPDV--NIEGPEGKWKSPKFKMP-----------EMH 2829 DV + AD + P CPDV N E P + F + E Sbjct: 3331 ADFSDVTVTPADFE-DVPVTPANCPDVPVNPESPVVSDLAVDFLVVPVVPSDDLVVLEPP 3389 Query: 2830 FKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPEVDLKGPKVDI---DVPDVNVQ 2886 K P + P + + I + T P V+G + P GP + D PDV + Sbjct: 3390 DKVPVVPDPISNGLVVSDPITNNTAATDPSVDGSVV-PVSPADGPVAPVTLADCPDVTIT 3448 Query: 2887 GPDWHLKMPKMKMPKFS-MPGFKAEGPEVDVNLPKADVDVSGPKVDVEGPDVNIEGPEGK 2945 D + +F +P A+ P V VN PK+ VS VD P V I P+ Sbjct: 3449 PADDSVVSDSKIRAEFEDVPVTIADCPNVPVN-PKSGPVVSDLAVDC--PVVPIPPPDDL 3505 Query: 2946 LKGPKFKMPEMNIKAPKIPMPDFD-LHLKGPKVKGDVDISLPKVEGDLKGPEVDIRGPQV 3004 + PE + P +P P D L + P G V S P ++G + P V G V Sbjct: 3506 VA------PEPPDEVPVVPDPITDSLVVSDPMTDGPV-ASDPSIDG-IVVPVVSPSGLLV 3557 Query: 3005 DIDVPDVGVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVN--LPK-----ADLDVSGPK 3057 V DV + PD +P + PD V LP DL V G Sbjct: 3558 LDSVADVSIL-PDTSADVPVTPVTLADGSVVPDSAPDCPVVPVLPTDGFVVLDLLVDGVV 3616 Query: 3058 V----DID--VPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPD----IDLNLKG---PK 3104 V D+ VPD +GP+ P P + ++ D +D + G P Sbjct: 3617 VPNPADVGPVVPDPTTDGPDSIKDFPLVPDPWPDCPVVPVTRTDGPVVLDSSADGVVVPV 3676 Query: 3105 VKGDMDVSLPKVEGDMKVPDVDIKGPKVDINAPDVDVQGP 3144 GD V+L ++ VPD+ GP V PD GP Sbjct: 3677 TPGDDSVALVTPTDNLVVPDLTTDGPVV----PDPSADGP 3712 Score = 52.4 bits (124), Expect = 1e-05 Identities = 203/877 (23%), Positives = 297/877 (33%), Gaps = 158/877 (18%) Query: 588 DVTLPRVEGKVKVPEVDVRGPKVDVSAPDVEAHGPEWNLKMPKMKMPTFSTPGAKG---- 643 DV + V G V VP++ P V V D L P + STP G Sbjct: 2906 DVPVNPVNGPV-VPDLSGDCPVVPVPPTDDIVV-----LNPPDVVFAVVSTPVTDGPVVT 2959 Query: 644 ----EGPDVHMTLPKGDISISGPKVNVEAPDVNLEGLGGKLKGPDVK---LPDMSVKTPK 696 +G V +T G ++ P E PDV + G + P + +PD S + Sbjct: 2960 DPATDGLMVPVTPANGSVA---PVTLSEYPDVTVTPADGTVVSPTIGGPVVPDPSADSSV 3016 Query: 697 ISMPDVDLHVKGTKVKGEYDVTVPKLEGELKGPKVDIDAPDVDVHGPDWHLKMPKMK--- 753 +S P D + + V V +G L P + D PDV V D + Sbjct: 3017 VSNPTTDGLIVPNPLLAGPVVPVTPTDGPL-APVILADCPDVTVTPADGPVVCAFTTGGP 3075 Query: 754 -MPKFSVPGFKAEGPEVD---VNLPKADVDISG--------PKIDVTAPDVSIEEPEGKL 801 P + G P VD V P +S P I PDV + + Sbjct: 3076 VFPDPTAEGLVVSNPTVDDPVVTNPSTKGLVSATPADCADVPVIPADCPDVLVNLVNDSV 3135 Query: 802 KGPKFKMPEMNIKVPKISMPDVDLHLKGPNVKGEYDVTMPKVESEIKVPDVELKSAKMDI 861 P F + V +S PD L P+ E V + + VPD+ + + Sbjct: 3136 V-PDFTA---DWTVVSVSPPD---DLVAPDPPDEVPVVLVPITDGPVVPDLTTDGLVVSV 3188 Query: 862 -------------DVPDVEVQGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDI 908 D PDV V D P + P P A+ + D +P D Sbjct: 3189 TPAGAPVVPVFLTDCPDVTVTPAD----SPVVPDPSSDGP-VVADSLDDDGLVPVTPADD 3243 Query: 909 S----GPKVGVEVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDVDLHMKGPKVKGEY 964 S P G+ VPD +GP P+ ++ P + + D Sbjct: 3244 SVVPDSPANGLVVPDPTTDGPVA---------PDPSVDGPVVPVTPADAP---------- 3284 Query: 965 DMTVPKLEGDLKGPKVDVSAPDVEMQGPDWNLKMPKIKMPKFSMPSLKGEGPEF-DVNLS 1023 TV D P V V+ PD + D P + + P + +F DV ++ Sbjct: 3285 --TVSVTLADC--PDVTVTPPD-GLVVSDSKRGGPVVTGLSTNDPVITATPADFSDVTVT 3339 Query: 1024 KANVDISAPKVDTNAPDLSLEGPEGKLKG---------PKFKMPEMHFRAPKMSLPDVDL 1074 A+ + P N PD+ + PE + P ++ P +P V Sbjct: 3340 PADFE-DVPVTPANCPDVPVN-PESPVVSDLAVDFLVVPVVPSDDLVVLEPPDKVPVVPD 3397 Query: 1075 DLKG-----PKMKGNVDISAPKIEGEMQVPDVDIRGPKVDIK---APDVEGQGLDWSLKI 1126 + + N + P ++G + VP GP + PDV D S+ Sbjct: 3398 PISNGLVVSDPITNNTAATDPSVDGSV-VPVSPADGPVAPVTLADCPDVTITPADDSVVS 3456 Query: 1127 PKMKMPKFS-MPSLKGEGPEVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKM 1185 +F +P + P V VN PK+ VVS VD P V + P+ + Sbjct: 3457 DSKIRAEFEDVPVTIADCPNVPVN-PKSGPVVSDLAVD--CPVVPIPPPDDLVA------ 3507 Query: 1186 PEMHFKTPKISMPDVD-LHLKGPKVKGDVDVSVPKVEGEMKVPDVEIKGPKMDIDAPDVE 1244 PE + P + P D L + P G V S P ++G + VP V G + DV Sbjct: 3508 PEPPDEVPVVPDPITDSLVVSDPMTDGPV-ASDPSIDG-IVVPVVSPSGLLVLDSVADVS 3565 Query: 1245 VQGPDWHLKMPKMKM------------------PKFSMPGFKGEGREVDVNLPKADIDVS 1286 + PD +P + P GF VD + DV Sbjct: 3566 IL-PDTSADVPVTPVTLADGSVVPDSAPDCPVVPVLPTDGFVVLDLLVDGVVVPNPADV- 3623 Query: 1287 GPKVDVEVPDVSLEGPEGKLKGPKFKMPEMHFKAPKISMPD----VDLNLKG---PKLKG 1339 GP V PD + +GP+ P P ++ D +D + G P G Sbjct: 3624 GPVV----PDPTTDGPDSIKDFPLVPDPWPDCPVVPVTRTDGPVVLDSSADGVVVPVTPG 3679 Query: 1340 DVDVSLPEVEGEMKVPDVDIKGPKVDISAPDVDVHGP 1376 D V+L + VPD+ GP V PD GP Sbjct: 3680 DDSVALVTPTDNLVVPDLTTDGPVV----PDPSADGP 3712 Score = 46.6 bits (109), Expect = 7e-04 Identities = 293/1320 (22%), Positives = 429/1320 (32%), Gaps = 288/1320 (21%) Query: 2830 FKTPKISMPDIDLNLTGPKIKGDVDVTGPKVEGDLKGPEVDLKGPKVDIDVPDVNVQGPD 2889 F T I +PD+ + P GD D P GD P + + VP GP Sbjct: 2688 FPTDGILVPDLADDPVVPVTPGD-DPVVPVTPGD--DPVIPVTPADDGPFVPVTPAVGP- 2743 Query: 2890 WHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVDVSGPKVDVEGPDVNIEGPEGKLKGP 2949 +P + +P + P + V P + V D +GP+V++ + GP Sbjct: 2744 ---VVPDLTADDSVVPDSLTDDPVISV-CPDDGLVVPDTVRDSDGPEVSVY----PVTGP 2795 Query: 2950 KFKMPEMNIKAPKIPMPDFDLHLKGP--------KVKGDVDISLPKVEGDL-KGPEVDIR 3000 + +P+ D + L P V + + P ++G + P VD Sbjct: 2796 VVTDSAADCPVVSVPLTDGLVVLCPPDEVPAVHDSVTNGLVVPDPVIDGPVFSNPSVD-- 2853 Query: 3001 GPQVDIDVPD-VGVQGPDWHLKMPKVKMPKFSMPGFKGEGPD-VDVNLPKADLDVSGPKV 3058 GP V + D GV PD P V P P D +DV + AD Sbjct: 2854 GPIVPVASADNPGV--PDPIRAFPVVPKPSTFSPVVTSTPADWIDVIVTPADC------- 2904 Query: 3059 DIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPDID--LNLKGPKVKGDMDVSLPKV 3116 DVP + GP +P+++ P + +P D + L P V + VS P Sbjct: 2905 -ADVPVNPVNGPV---------VPDLSGDCPVVPVPPTDDIVVLNPPDVVFAV-VSTPVT 2953 Query: 3117 EGD---------MKVPDVDIKGPKVDINA---PDVDVQGPDWHLKMPKIKMPKISMPGFK 3164 +G + VP G + PDV V D + P I P + P Sbjct: 2954 DGPVVTDPATDGLMVPVTPANGSVAPVTLSEYPDVTVTPADGTVVSPTIGGPVVPDPSAD 3013 Query: 3165 GE------------------GPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLK--- 3203 GP V V L P + D PDV + D + Sbjct: 3014 SSVVSNPTTDGLIVPNPLLAGPVVPVTPTDGPL---APVILADCPDVTVTPADGPVVCAF 3070 Query: 3204 ---GPKFKMPEMNIKAPKISMPDLDLNL-KGPKMKGEVDVSLANVEGDLKGPALDIKGPK 3259 GP F P+ + +S P +D + P KG V + A+ D+ P Sbjct: 3071 TTGGPVF--PDPTAEGLVVSNPTVDDPVVTNPSTKGLVSATPAD--------CADV--PV 3118 Query: 3260 IDVDAPDIDIHGPDAKLKGPKLKMPDMHVNMPKISMPEIDLNLKGSKLKGDVDVSGPKLE 3319 I D PD+ ++ + + +PD + +S+ D D+ P Sbjct: 3119 IPADCPDVLVNLVNDSV------VPDFTADWTVVSVSPPD------------DLVAPDPP 3160 Query: 3320 GDIKAPSLDIK-GPEVDVSGPKLNIEGKSKKSRFKLPKFNFSGSKVQTPEVDV-KGKKPD 3377 ++ + I GP V P L +G S + P V V PD Sbjct: 3161 DEVPVVLVPITDGPVV----PDLTTDG-----------LVVSVTPAGAPVVPVFLTDCPD 3205 Query: 3378 IDITGPKVDINAPDVEVQGKVKGSKFKMPFLSISSPKVS--MPDVELN-LKSPKVKGDLD 3434 + +T P PD G V L +P +PD N L P D Sbjct: 3206 VTVT-PADSPVVPDPSSDGPVVADSLDDDGLVPVTPADDSVVPDSPANGLVVPDPTTDGP 3264 Query: 3435 IA-GPNLEGDFKGPKVDIKAPEVNL---NAPDVDVHGPDWNLKMPKMKMPKFSVSGLKAE 3490 +A P+++G P AP V++ + PDV V PD L + K V+GL Sbjct: 3265 VAPDPSVDGPVV-PVTPADAPTVSVTLADCPDVTVTPPD-GLVVSDSKRGGPVVTGLSTN 3322 Query: 3491 GP----------DVAV------DLPKGDINIEGPSMNIEGP---DLNVEGPEGGLKGPKF 3531 P DV V D+P N +N E P DL V+ L P Sbjct: 3323 DPVITATPADFSDVTVTPADFEDVPVTPANCPDVPVNPESPVVSDLAVDF----LVVPVV 3378 Query: 3532 KMPDMNIKAPKISMPDIDLNLKGPKVKGDVDISLPKLEGDLKGPEVDIKGPKVDINAPDV 3591 D+ + P +P + + V D + + + + G V ++ D Sbjct: 3379 PSDDLVVLEPPDKVPVVPDPISNGLVVSD------PITNNTAATDPSVDGSVVPVSPAD- 3431 Query: 3592 DVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDVTLPKADIDISGPNVDVDVPDVNIE-GP 3650 GP VTL D PDV I Sbjct: 3432 ---------------------------GPVAPVTL-------------ADCPDVTITPAD 3451 Query: 3651 DAKLKGPKFKMPEMNIKAPKISMPDFDLNLKGPKMKGDVVVSLPKVE----GDLKGPEVD 3706 D+ + K + ++ P+ +N K + D+ V P V DL PE Sbjct: 3452 DSVVSDSKIRAEFEDVPVTIADCPNVPVNPKSGPVVSDLAVDCPVVPIPPPDDLVAPEPP 3511 Query: 3707 IKGPKVDIDTPDINIEGSEGKFKGPKFKIPEMHLKAPKISMPDIDLNLKGPKVKGDVDVS 3766 + P V D ++ S+ GP P + + P L L DV + Sbjct: 3512 DEVPVVPDPITD-SLVVSDPMTDGPVASDPSIDGIVVPVVSPSGLLVLDSV---ADVSI- 3566 Query: 3767 LPKMEGDLKGPEVDIK-GPKVDINAPDVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVD 3825 LP D+ V + G V +APD V +P GF VD Sbjct: 3567 LPDTSADVPVTPVTLADGSVVPDSAPDCPV-------------VPVLPTDGFVVLDLLVD 3613 Query: 3826 VNLPKADLDVSGPKVDIDVPDVNIEGPEGKLKGPKFKMPEMNIKAPKISMPD----IDLN 3881 + DV GP V PD +GP+ P P + ++ D +D + Sbjct: 3614 GVVVPNPADV-GPVV----PDPTTDGPDSIKDFPLVPDPWPDCPVVPVTRTDGPVVLDSS 3668 Query: 3882 LKG---PKVKGDMDVSLPKVEGDMQVPDLDIKGPKVDINAPDVDVRGPDWHLKMPKIKMP 3938 G P GD V+L ++ VPDL GP V Sbjct: 3669 ADGVVVPVTPGDDSVALVTPTDNLVVPDLTTDGPVV------------------------ 3704 Query: 3939 KISMPGFKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGP---DAKLKGPKFKMPEMN 3995 P +GP V V+L L + P D VP+ + P D P P N Sbjct: 3705 ----PDPSADGPVVLVSLADDLLVPNPPVKDTVVPNSVADNPVALDPVTDCPLVPEPSAN 3760 Query: 3996 IKAPKISMPDFDLHLKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKVDIDAPDVDVHGPD 4055 S+ + + P D V L L P++ GP V PD G D Sbjct: 3761 GLVVTDSLDEGPV---VPDPSADDPVVLNPETNGLVVPDISANGPVV----PDTPTDGSD 3813 Score = 37.7 bits (86), Expect = 0.34 Identities = 242/1174 (20%), Positives = 374/1174 (31%), Gaps = 268/1174 (22%) Query: 1126 IPKMKMPKFSMPSLKGEGPEVDVNLPKADVVVSGPKVDIEAPDVSLEGPEGKLKGPKFKM 1185 +P + +P + P + V P +VV D + P+VS+ G + + Sbjct: 2745 VPDLTADDSVVPDSLTDDPVISV-CPDDGLVVPDTVRDSDGPEVSVYPVTGPV------V 2797 Query: 1186 PEMHFKTPKISMPDVD-LHLKGPKVKGDVDVSVPKVEGEMKVPDVEIKGPKMD---IDAP 1241 + P +S+P D L + P +V V + VPD I GP +D P Sbjct: 2798 TDSAADCPVVSVPLTDGLVVLCPP--DEVPAVHDSVTNGLVVPDPVIDGPVFSNPSVDGP 2855 Query: 1242 DVEVQG------PDWHLKMPKMKMPKFSMPGFKGEGREVDVNLPKADIDVSGPKVDVEVP 1295 V V PD P + P P V + P IDV + P Sbjct: 2856 IVPVASADNPGVPDPIRAFPVVPKPSTFSP--------VVTSTPADWIDV------IVTP 2901 Query: 1296 DVSLEGPEGKLKGPKFKMPEMHFKAPKISMPDVD----LN--------LKGPKLKGDVDV 1343 + P + GP +P++ P + +P D LN + P G V V Sbjct: 2902 ADCADVPVNPVNGPV--VPDLSGDCPVVPVPPTDDIVVLNPPDVVFAVVSTPVTDGPV-V 2958 Query: 1344 SLPEVEGEMKVPDVDIKGPKVDISA---PDVDVHGPDWHLKMPKVKMPKFSMPGFKGE-- 1398 + P +G M VP G ++ PDV V D + P + P P Sbjct: 2959 TDPATDGLM-VPVTPANGSVAPVTLSEYPDVTVTPADGTVVSPTIGGPVVPDPSADSSVV 3017 Query: 1399 ----------------GPEVDVKLPKADVDVSGPKMDAEVPDVNIEGPDAKLK------G 1436 GP V V + P + A+ PDV + D + G Sbjct: 3018 SNPTTDGLIVPNPLLAGPVVPVTPTDGPL---APVILADCPDVTVTPADGPVVCAFTTGG 3074 Query: 1437 PKFKMPEMSIKPQKISIPDVGLHLKGPKMKGDYDVTVPKVEGEIKAPDVDIKG-PKVDIN 1495 P F P GL + P + D VT P +G + A D P + + Sbjct: 3075 PVFPDPTAE-----------GLVVSNPTVD-DPVVTNPSTKGLVSATPADCADVPVIPAD 3122 Query: 1496 APDVEVHGPDWHLKMPKVKMPKFSMPGFKGEGPEVDMNLPKADLGVSGPKVDIDVPDVNL 1555 PDV V+ + +P F + V ++ P + P +VP V + Sbjct: 3123 CPDVLVN-----------LVNDSVVPDFTADWTVVSVSPPD---DLVAPDPPDEVPVVLV 3168 Query: 1556 EAPEGKLKGPKFKMPSMNIQTHKISMPDVGLNLKAPKLKTDVDVSLPKVEGDLKGPEIDV 1615 +G + +P + +S+ G + L DV++ + + V Sbjct: 3169 PITDGPV------VPDLTTDGLVVSVTPAGAPVVPVFLTDCPDVTVTPADSPV------V 3216 Query: 1616 KAPKMD--VNVGDIDIEGPEGKLKGPKFKMPEMHFKAPKISMPDVDLHLKGPKVKGDMDV 1673 P D V +D +G +P+ + P D GP Sbjct: 3217 PDPSSDGPVVADSLDDDGLVPVTPADDSVVPDSPANGLVVPDPTTD----GPVAPD---- 3268 Query: 1674 SVPKVEGEMKVPDVDIKGPKVDI---DAPDVEVHDPDWHLKMPKMKMPKFSMPGFKAEGP 1730 P V+G + VP P V + D PDV V PD L + K + G P Sbjct: 3269 --PSVDGPV-VPVTPADAPTVSVTLADCPDVTVTPPDG-LVVSDSKRGGPVVTGLSTNDP 3324 Query: 1731 EVDVNLPKADIDVSGPSVDTDAPDLDIEGPEGKLKGSKFKMPKLNIKAPKVSMPDVDLNL 1790 + AD D D E ++ + PDV +N Sbjct: 3325 VITAT--PADFS------DVTVTPADFE----------------DVPVTPANCPDVPVNP 3360 Query: 1791 KGPKLKGEIDASVPELEGDLRGPQVDVKGPFVEAEVPDVDLECPDAKLKGPKFKMPEMHF 1850 + P V +L D V V E PD Sbjct: 3361 ESPV--------VSDLAVDFLVVPVVPSDDLVVLEPPD---------------------- 3390 Query: 1851 KAPKISMPDVDLHLKGPKVKGDADVSVPKLEGDLT--GPSVGVEVPDVELECPDAKLKGP 1908 K P + P + + + + + P ++G + P+ G P +CPD + Sbjct: 3391 KVPVVPDPISNGLVVSDPITNNTAATDPSVDGSVVPVSPADGPVAPVTLADCPDVTIT-- 3448 Query: 1909 KFKMPDMHFKAPKISMPDVDLHLKGPKVKG---DVDVSVPKLEGDLTGPSVGVEVPDVEL 1965 P D + K++ DV V++ P G V D+ + Sbjct: 3449 ----------------PADDSVVSDSKIRAEFEDVPVTIADCPNVPVNPKSGPVVSDLAV 3492 Query: 1966 ECPDAKLKGPK-FKMPEMHFKTPKISMPDVD-LHLKGPKVKGDMDVSVPKVEGEMKVPDV 2023 +CP + P PE + P + P D L + P G + S P ++G + VP V Sbjct: 3493 DCPVVPIPPPDDLVAPEPPDEVPVVPDPITDSLVVSDPMTDGPV-ASDPSIDG-IVVPVV 3550 Query: 2024 DIKGPKMDIDAPDVDVHGPDWHLKMPKMKMPKFSMPGFKAEGPEVDVNLPKADVVVSGPK 2083 G + DV + PD +P P A+G V + P VV P Sbjct: 3551 SPSGLLVLDSVADVSIL-PDTSADVPVT-------PVTLADGSVVPDSAPDCPVVPVLPT 3602 Query: 2084 VDVEVPDVSLEGPEGKLKGPKLKMPEMHFKAPKISMPDVDLHLKGPKVKGDVDVSLPKLE 2143 V D+ ++G + +P P + P D GP D + Sbjct: 3603 DGFVVLDLLVDG---------VVVPNPADVGPVVPDPTTD----GPDSIKDFPL------ 3643 Query: 2144 GDLTGPSVDVEVPDVELECPDAKLKGPKFKMPEMHFKTPKISMPDVNLNLKGPKVKGDMD 2203 VPD +CP +P P + + + P GD Sbjct: 3644 -----------VPDPWPDCP---------VVPVTRTDGPVVLDSSAD-GVVVPVTPGDDS 3682 Query: 2204 VSVPKVEGEMKVPDVDIRGPKVDIDAPDVDVHGP 2237 V++ + VPD+ GP V PD GP Sbjct: 3683 VALVTPTDNLVVPDLTTDGPVV----PDPSADGP 3712 >gi|224589132 hypothetical protein LOC100132406 [Homo sapiens] Length = 3628 Score = 58.2 bits (139), Expect = 2e-07 Identities = 241/1236 (19%), Positives = 447/1236 (36%), Gaps = 173/1236 (13%) Query: 3833 LDVSGPKVDIDVPDVNIEGPEGKLK--------GPKFKMPEMNIKAPKISMPDIDLNLKG 3884 LD GP+V D D P G L+ F + E + M +I+ K Sbjct: 2090 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIE---KY 2146 Query: 3885 PKVKGDMDVSLPKVEGDMQVPDLDIKGPKVDINAPDVDVRGPDWHLKMPKIKMPKISMPG 3944 +V+ D D S P++ ++ LD K P+V ++ D P +L++P + P Sbjct: 2147 QEVEEDQDPSCPRLSREL----LDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP------ 2196 Query: 3945 FKGEGPEVDVNLPKADLDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMNIKAPKISMP 4004 + ++ LDV ++ D + +GP P+ + + P++ Sbjct: 2197 YSSAVYSLEEQYLGLALDVD--RIKKDQEEEEDQGPPC----PRLSRELLEVVEPEVLQD 2250 Query: 4005 DFDLHLKGPKVKGDVDVSLPKMEGDLKAPEVDIKGPKVDIDAPDVDVHGPDWHLKMPKVK 4064 D P + S A E + G +D+ + G + K + Sbjct: 2251 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKE 2310 Query: 4065 MPKFSMPGFKGEGPEVDVNLPKADIDVSGPKVDIDTPDIDIHGPEGKLK--------GPK 4116 + G + + P L + +D GP+V D+ D P G L+ Sbjct: 2311 RRRGRKEGEEDQNPPCP-RLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSA 2369 Query: 4117 FKMPDLHLKAPKISMPEVDLNLKGPKMKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDVPD 4176 F + + + M E++ K +++ D D S P++ +L +D K P+V D D Sbjct: 2370 FYVLEQQHVGLAVDMDEIE---KYQEVEEDQDPSCPRLSREL----LDEKEPEVLQDSLD 2422 Query: 4177 VDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADLDVSGPKVDIDVPDVNIEGP 4236 P +L++P + P +S + E + + L D+D ++ D + +GP Sbjct: 2423 RCYSTPSGYLELPDLGQP-YSSAVYSLEEQYLGLAL---DVD----RIKKDQEEEEDQGP 2474 Query: 4237 DAKLKGPKFKMPEMNIKAPKISMPDFDLHLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGP 4296 P+ + + P++ D P + S E + G Sbjct: 2475 PC----PRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGF 2530 Query: 4297 KVDIDAPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVTLPKADIEISGPKVDIDA 4356 +D+ + G + K + + G + + P L + ++ GP+V D+ Sbjct: 2531 SLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCP-RLSRELLDEKGPEVLQDS 2589 Query: 4357 PDVSIEGPDAKLK--------GPKFKMPEMNIKAPKISMPDIDFNLKGPKVKGDVDVSLP 4408 D P L+ F + E + M +I+ K +V+ D D S P Sbjct: 2590 LDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIE---KYQEVEEDQDPSCP 2646 Query: 4409 KVEGDLKGPEIDIKGPSLDIDTPDVNIEGPEGKLKGPKFKMPEMN----IKAPKISMP-D 4463 ++ +L +D K P + D+ D P G L+ P P + ++ + + D Sbjct: 2647 RLSREL----LDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALD 2702 Query: 4464 FDLHLKGPKVKGDVDVSLPKVESDL-----------------KGPEVDIEGPEG-KLKGP 4505 D K + + D P++ +L P +E P+ + G Sbjct: 2703 VDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGS 2762 Query: 4506 KFKMPDVHFKSPQISMSDIDLNLKGPKIKG----------------DMDISVPKLEGDLK 4549 F + + + +I+ KG K +G D + P+L +L Sbjct: 2763 SFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL- 2821 Query: 4550 GPKVDVKGPKVGIDTPDIDIHGPEGKLK--------GPKFKMPDLHLKAPKISMPEVDLN 4601 +D KGP+V D+ D P G L+ F + + + M E++ Sbjct: 2822 ---LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIE-- 2876 Query: 4602 LKGPKVKGDMDISLPKVEGDLKGPEVDIRDPKVDIDVPDVDVQGPDWHLKMPKVKMPKFS 4661 K +V+ D D S P++ +L +D ++P+V D D P +L++P + P +S Sbjct: 2877 -KYQEVEEDQDPSCPRLSREL----LDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP-YS 2930 Query: 4662 MPGFKGEGPDVDVNLPKADIDVSGPKVDVDVPDVNIEGPDAKLKGPKFKMPEMSIKAPKI 4721 + E + + L D+D ++ D + +GP P+ + + P++ Sbjct: 2931 SAVYSLEEQYLGLAL---DVD----RIKKDQEEEEDQGPPC----PRLSRELLEVVEPEV 2979 Query: 4722 SMPDIDLNLKGPKVKGDVDVTLPKVEGDLKGPEADIKGPKVDINTPDVDVHGPDWHLKMP 4781 +D P + + E G +D+ + G + Sbjct: 2980 LQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRS 3039 Query: 4782 KVKMPKFSMPGFKGEGPDVDVSLPKADIDVSGPKVDVDIPDVNIEGPDAKLK----GPKF 4837 K + + G + + P L + +D GPKV D D P L+ + Sbjct: 3040 KKERRRGRKEGEEDQNPPCP-RLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPY 3098 Query: 4838 KMPEINIKAPKISIP-DVDLDLKGPKVKGDFDVSVPKVEGTLKGPEVDLKGPRLDFEGPD 4896 + ++ ++ + D+D K +V+ D D S P++ L +D KGP + + D Sbjct: 3099 RSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSREL----LDEKGPEVLQDSLD 3154 Query: 4897 AKLSGPSLKMPSLEISAPKVTAPDVDLHLKAPKIGF-------------------SGPKL 4937 S PS + + P +A + L+ ++G S P+L Sbjct: 3155 RCYSTPSGCLELCDSCQPYRSAFYI---LEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRL 3211 Query: 4938 EGGEVDLKGPKVEAPSLDVHMDSPDINIEGPDVKIP 4973 +D K P+V SLD +P +E PD+ P Sbjct: 3212 SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 3247 Score = 42.4 bits (98), Expect = 0.014 Identities = 161/806 (19%), Positives = 293/806 (36%), Gaps = 133/806 (16%) Query: 4335 DVDVTLPKADIEI---SGPKVDIDAPDVSIEGPDAKLKGPKFKMPEMN----IKAPKISM 4387 D + T P+ E+ GP+V D+ D P L+ P + ++ ++ + Sbjct: 611 DQEATGPRLSRELLDEKGPEVFQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGL 670 Query: 4388 P-DIDFNLKGPKVKGDVDVSLPKVEGDLKGPEIDIKGPSLDIDTPDVNIEGPEGKLKGPK 4446 D+D K +V+ D D S P++ +L +D K P + D+ D P G L+ P Sbjct: 671 AIDMDEIEKYQEVEEDQDPSCPRLSREL----LDEKEPEVLQDSLDRCYSTPSGYLELPD 726 Query: 4447 FKMPEMN----IKAPKISMP-DFDLHLKGPKVKGDVDVSLPKVESDL------------- 4488 P + ++ + + D D K + + D P++ +L Sbjct: 727 LGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSL 786 Query: 4489 ----KGPEVDIEGPEG-KLKGPKFKMPDVHFKSPQISMSDIDLNLKGPKIKG-------- 4535 P +E P+ + G F + + + +I+ KG K +G Sbjct: 787 DRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERR 846 Query: 4536 --------DMDISVPKLEGDLKGPKVDVKGPKVGIDTPDIDIHGPEGKLK--------GP 4579 D + P+L +L +D KGP+V D+ D P G L+ Sbjct: 847 RGRKEGEEDQNPPCPRLSREL----LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRS 902 Query: 4580 KFKMPDLHLKAPKISMPEVDLNLKGPKVKGDMDISLPKVEGDLKGPEVDIRDPKVDIDVP 4639 F + + + M E++ K +V+ D D S P++ +L +D ++P+V D Sbjct: 903 AFYVLEQQRVGFAVDMDEIE---KYQEVEEDQDPSCPRLSREL----LDEKEPEVLQDSL 955 Query: 4640 DVDVQGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVNLPKADIDVSGPKVDVDVPDVNIEG 4699 D P +L++P + P +S + E + + L D+D ++ D + +G Sbjct: 956 DRCYSTPSGYLELPDLGQP-YSSAVYSLEEQYLGLAL---DVD----RIKKDQEEEEDQG 1007 Query: 4700 PDAKLKGPKFKMPEMSIKAPKISMPDIDLNLKGPKVKGDVDVTLPKVEGDLKGPEADIKG 4759 P P+ + + P++ +D P + + E G Sbjct: 1008 PPC----PRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVG 1063 Query: 4760 PKVDINTPDVDVHGPDWHLKMPKVKMPKFSMPGFKGEGPDVDVSLPKADIDVSGPKVDVD 4819 +D+ + G + K + + G + + P L + +D GP+V D Sbjct: 1064 FSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCP-RLSRELLDEKGPEVLQD 1122 Query: 4820 IPDVNIEGPDAKLKGPKFKMPEIN----IKAPKISIP-DVDLDLKGPKVKGDFDVSVPKV 4874 D P L+ P + ++ ++ D+D K +V+ D D S P++ Sbjct: 1123 SLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRL 1182 Query: 4875 EGTL---KGPEVDLKGPRLDFEGPDAKLSGPSLKMP-------------SLEISAPKVTA 4918 L K PEV + P L P L P L + ++ Sbjct: 1183 SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKK 1242 Query: 4919 PDVDLHLKAPKIGFSGPKLEGGEVDLKGPKVEAPSLDVHMDSPDINIEGPDVKIPKFKKP 4978 + + + P P+L +++ P+V SLD +P +E PD P Sbjct: 1243 DEEEEEDQDPPC----PRLSRELLEVVAPEVLQDSLDRCYSTPSSCLEQPDSCQP----- 1293 Query: 4979 KFGFGAKSPKADIKSPSLDVTVPEAELNLETPEISVGGKGKKSKFKMPKIHMSGPKIKAK 5038 +G+ + K +L+ EI GKGKK + + K + + + Sbjct: 1294 ---YGSSFYALEEK---------HVGFSLDVGEIEKKGKGKKRRGRRSK----KERRRGR 1337 Query: 5039 KQG-FDLNVPGGEIDASL---KAPDV 5060 K+G D N P + L K P+V Sbjct: 1338 KEGEEDQNPPCPRLSRELLDEKGPEV 1363 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 58.2 bits (139), Expect = 2e-07 Identities = 128/444 (28%), Positives = 167/444 (37%), Gaps = 75/444 (16%) Query: 5206 PKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGD 5265 P +KG+ G GP+ GP+ + + G PG G LP G Sbjct: 383 PGMKGEAGPTGARGPE----GPQGQ-------RGETGPPGPVGSPG-------LPGAIGT 424 Query: 5266 LRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDL-DASVPSMKV 5324 P K GP S PG P + P GP +G ++G D VP K Sbjct: 425 DGTPGAK--GPTGS---PGTSGPPGSAGPPGSPGPQGSTGPQG--IRGQPGDPGVPGFKG 477 Query: 5325 HAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAP-DVTLRGPSLQGDLAVSGDIKCP 5383 A G K + G G++ P +G P + RGP +GD G P Sbjct: 478 EA--------GPKGEPGPHGIQGP---------IGPPGEEGKRGP--RGDPGTVGP-PGP 517 Query: 5384 KVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLK 5443 GAP GS LP K Q G V + GP+ S G + L Sbjct: 518 VGERGAP--GNRGFPGSDGLPGPKGAQ------GERGPVGSSGPKGSQGDPGRPGEPGLP 569 Query: 5444 GPRISAPNVDFNLEGPKVK-GSLGATGEIKGPTVGGGLPG-IGVQGLEGNLQMPGIKSSG 5501 G R N ++GP+ K G LGA GE P G PG IG++G G++ +PG K S Sbjct: 570 GARGLTGNP--GVQGPEGKLGPLGAPGEDGRP----GPPGSIGIRGQPGSMGLPGPKGSS 623 Query: 5502 CDVNLPGV--NVKLPTGQISGPEIKGGLKGS-EVGFHGAAPDISVKGPAFNMASPESDFG 5558 D PG N +P GQ P G + S VG G A + +GP P G Sbjct: 624 GDPGKPGEAGNAGVP-GQRGAPGKDGEVGPSGPVGPPGLAGERGEQGP----PGPTGFQG 678 Query: 5559 I-NLKGPKIKGGADVSGGVSAPDISLGE-GHLSVKGSGGEWKGPQVSSALNLDTSKFAGG 5616 + GP +GG GV ++G G +G+ GE P ++ AGG Sbjct: 679 LPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPG--EKGMAGG 736 Query: 5617 LHFSGPKVEGGVKGGQIGLQAPGL 5640 GPK G G PGL Sbjct: 737 HGPDGPKGSPGPSGTPGDTGPPGL 760 Score = 38.9 bits (89), Expect = 0.15 Identities = 101/380 (26%), Positives = 130/380 (34%), Gaps = 59/380 (15%) Query: 203 KTVIRLPSGSGAASPTGSAVDIRAGAISASGPE----------LQGAGHSKLQVTMPGIK 252 K + P G A PTG GA+ GP QGA + MPG K Sbjct: 311 KGEVGAPGSKGEAGPTGPM-----GAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPG-K 364 Query: 253 VGGSGVNVNAKGLDLGGRGGVQVPAVDISSSLGGRAVE-VQGPSLESGDHGKIKFPTMKV 311 G G G G++ A G R E QG E+G G + P + Sbjct: 365 PGPMGPLGIPGSSGFPGNPGMKGEA----GPTGARGPEGPQGQRGETGPPGPVGSPGLPG 420 Query: 312 PKFGVST-GREGQTPKAGLRVSAPEVSVGHKGGKPGLTIQAPQLEVSVPSANIEGLEGKL 370 T G +G T G S P S G G PG PQ S +G+ G+ Sbjct: 421 AIGTDGTPGAKGPTGSPG--TSGPPGSAGPPGS-PG-----PQ-----GSTGPQGIRGQP 467 Query: 371 KGPQITGPSLEGDLGLKGAKP----QGHIGVDASAPQIGGSITGPSVEVQAPDIDVQGPG 426 P + P +G+ G KG QG IG + G +V P + PG Sbjct: 468 GDPGV--PGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPG 525 Query: 427 SKLNVPKMKVPKFSVSGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLEGKMKGT 486 ++ +P GA+GE + + P G PG G+ LP G G Sbjct: 526 NRGFPGSDGLP--GPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLP-----GARGLTGNP 578 Query: 487 KVKTPEMIIQKPKISMQDVDLSLGSPKLKGDIKV-SAPGVQGDVKGPQVALKGSRVDIET 545 V+ PE K+ G P G I + PG G + GP KGS D Sbjct: 579 GVQGPE-----GKLGPLGAPGEDGRPGPPGSIGIRGQPGSMG-LPGP----KGSSGDPGK 628 Query: 546 PNLEGTLTGPRLGSPSGKTG 565 P G P GK G Sbjct: 629 PGEAGNAGVPGQRGAPGKDG 648 Score = 38.9 bits (89), Expect = 0.15 Identities = 124/484 (25%), Positives = 164/484 (33%), Gaps = 115/484 (23%) Query: 5206 PKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSLEGD 5265 P KGD +G +G + A+ G+PG G A P+ E Sbjct: 773 PGPKGDRGGIGEKGAEGTAGNDGAR-----------GLPGPLGPPGPAG-----PTGEKG 816 Query: 5266 LRGPDVKLEGPDVSLKGPGV---DLPSVNLSMPKVSGPDLDLNLKG----PSLKGDLDAS 5318 GP L GP S PG + P+ + GPD +KG P KGD + Sbjct: 817 EPGPR-GLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSP 875 Query: 5319 VPSMKVHAPGLN-LSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVS 5377 P +PG + +GV G GG G + P P G + Sbjct: 876 GPQGLAGSPGPHGPNGVPGLK--GGRGTQGP-------------------PGATGFPGSA 914 Query: 5378 GDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPG 5437 G + P GAP G + P + P PGS V +GP +G GPG Sbjct: 915 GRVG-PPGPAGAP-----GPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGP--AGPPGGPG 966 Query: 5438 VDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPG-IGVQGLEGNLQMPG 5496 KG G G+ GP G PG G G G + MPG Sbjct: 967 D-----------------------KGDPGEDGQ-PGPD---GPPGPAGTTGQRGIVGMPG 999 Query: 5497 IKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKG-----SEVGFHGAAPDISVKGPAFNMA 5551 + + +PG+ T GP G KG G +G + +GPA N Sbjct: 1000 QRG---ERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDG 1056 Query: 5552 SPESDFGINLKGPK-IKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDT 5610 +P D + +G + G A + G AP G + G G+ P S + Sbjct: 1057 TPGRDGAVGERGDRGDPGPAGLPGSQGAPGT---PGPVGAPGDAGQRGDP--GSRGPIGP 1111 Query: 5611 SKFAGGLHFSGPKVEGGVKG--------------GQIGLQA-PGLSVSGPQGHLESGSGK 5655 AG GP+ G KG G GLQ PG GP G E GS Sbjct: 1112 PGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPG--PPGPNG--EQGSAG 1167 Query: 5656 VTFP 5659 + P Sbjct: 1168 IPGP 1171 Score = 36.2 bits (82), Expect = 0.99 Identities = 126/466 (27%), Positives = 163/466 (34%), Gaps = 79/466 (16%) Query: 5209 KGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGG-----GAEVHAQLPSLE 5263 KG+ G++GP + G E K + P+ +G PG E G G LP + Sbjct: 482 KGEPGPHGIQGP-IGPPGEEGK-RGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPK 539 Query: 5264 GDL--RGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLK-GDLDASVP 5320 G RGP V GP S PG +P G + ++GP K G L A Sbjct: 540 GAQGERGP-VGSSGPKGSQGDPG---RPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGE 595 Query: 5321 SMKVHAPG-LNLSGVGGKMQVGGDGVKV--PGIDATTKLNVGAPDVTLRG-PSLQGDLAV 5376 + PG + + G G M + G PG N G P RG P G++ Sbjct: 596 DGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAG-NAGVPGQ--RGAPGKDGEVGP 652 Query: 5377 SGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQF------GISTPGSDLHVNAKGPQVS 5430 SG + P ++ + G LP P PG V GP+ Sbjct: 653 SGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGE 712 Query: 5431 ----GELKGPGVDVNLKGPRISA----PNVDFNLEGPK----------VKGSLGATGEIK 5472 GE PG+ L G + A P+ GP ++G G G Sbjct: 713 RGNPGERGEPGI-TGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAG 771 Query: 5473 GPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEV 5532 P G GIG +G EG G + LPG P G GP G KG E Sbjct: 772 TPGPKGDRGGIGEKGAEGTAGNDGAR------GLPG-----PLGP-PGPAGPTGEKG-EP 818 Query: 5533 GFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGEGHLSVKG 5592 G G + GP + +P S +G GA G PD G VKG Sbjct: 819 GPRG------LVGPPGSRGNPGS------RGENGPTGAVGFAGPQGPD-----GQPGVKG 861 Query: 5593 SGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQAP 5638 GE Q A + AG GP G+KGG+ G Q P Sbjct: 862 EPGE--PGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGR-GTQGP 904 Score = 35.4 bits (80), Expect = 1.7 Identities = 68/259 (26%), Positives = 87/259 (33%), Gaps = 41/259 (15%) Query: 5416 PGSDLHVNAKGPQ-VSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGP 5474 PGS V +GPQ + G+ G G P P GP+ G G GE P Sbjct: 212 PGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPE--GPPGKPGEDGEP 269 Query: 5475 TVGG--------------GLPGI-GVQGLEGNLQMPGIKSSGCDVNLPGVNVKL-PTGQI 5518 G G PG G+ GL+G+ G++ +V PG + PTG + Sbjct: 270 GRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPM 329 Query: 5519 S-----GPEIKGGLKG-----SEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKG 5568 GP G +G G GA GP + P S G K + Sbjct: 330 GAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEA 389 Query: 5569 GADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGV 5628 G + G P GE G G P + A+ D + A GP G Sbjct: 390 GPTGARGPEGPQGQRGE-----TGPPGPVGSPGLPGAIGTDGTPGA-----KGPTGSPGT 439 Query: 5629 KGGQIGLQAPGLSVSGPQG 5647 G PG GPQG Sbjct: 440 SGPPGSAGPPG--SPGPQG 456 >gi|126352608 elastin isoform e precursor [Homo sapiens] Length = 705 Score = 57.0 bits (136), Expect = 5e-07 Identities = 123/469 (26%), Positives = 163/469 (34%), Gaps = 63/469 (13%) Query: 5210 GDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPS---LEGDL 5266 G VP VG G P+ +P +G+PGV GG A+ P L G Sbjct: 113 GGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGV--YPGGVLPGARFPGVGVLPGVP 170 Query: 5267 RGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKV-- 5324 G VK + P V G +P V G L +K P L G + K+ Sbjct: 171 TGAGVKPKAPGVG--GAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPY 228 Query: 5325 -HAPGLNLSGVGGK------MQVGGDGVKVPGIDATTKLNVGA----PDVTLRG-PSLQG 5372 + PG ++G GK VG A K GA P V G P + G Sbjct: 229 GYGPG-GVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG 287 Query: 5373 DLAVSGDIK---CPKVSVGAPDLSLEASEGSIKLPKMKLPQFG---ISTPGSDLHVNAKG 5426 + G I P + A + A G+ P FG + PG+ V G Sbjct: 288 AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAG--VPGVG 345 Query: 5427 PQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVG--------- 5477 +G PG + P + P V K G G VG Sbjct: 346 VPGAGIPVVPGAGI----PGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGA 401 Query: 5478 GGLP--GIGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFH 5535 GG P G+GV G+ G +PG+ +PGV + P Q + K G G Sbjct: 402 GGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGIS-PEAQ-AAAAAKAAKYGLVPGV- 458 Query: 5536 GAAPDISVKGPAFNMASPESDFGINL-KGPKIKGGADVSGGVS-APDISLGEGHLSVKGS 5593 G AP + V P +A G+ L G + G V+ GV AP I G + K + Sbjct: 459 GVAPGVGV-APGVGVAP-----GVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSA 512 Query: 5594 GGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQAPGLSV 5642 Q+ +A L G G V GV G +G PGL V Sbjct: 513 AKVAAKAQLRAAAGL-------GAGIPGLGVGVGVPGLGVGAGVPGLGV 554 Score = 38.1 bits (87), Expect = 0.26 Identities = 88/316 (27%), Positives = 126/316 (39%), Gaps = 55/316 (17%) Query: 5185 PSFG---ISAPQVSIPDVNVNLKGPKIKGDVPSVGLEGPDVD-LQGPEAKIKFP----KF 5236 P FG + P +P V V G + VP G+ G V + PEA K K+ Sbjct: 327 PGFGPGVVGVPGAGVPGVGVPGAGIPV---VPGAGIPGAAVPGVVSPEAAAKAAAKAAKY 383 Query: 5237 -SMPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVD-LPSVNLSM 5294 + P +G+ G+ G GA G G V + G PGV +P V + Sbjct: 384 GARPGVGVGGIPTYGVGA----------GGFPGFGVGVGGIPGVAGVPGVGGVPGVG-GV 432 Query: 5295 PKVS-GPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLS-GVGGKMQVG---GDGVKVPG 5349 P V P+ + K L VP + V APG+ ++ GVG VG G GV PG Sbjct: 433 PGVGISPEAQAAAAAKAAKYGL---VPGVGV-APGVGVAPGVGVAPGVGLAPGVGV-APG 487 Query: 5350 IDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEG-SIKLPKMKL 5408 + + V AP + GP G +A + KV+ A L A+ G +P + + Sbjct: 488 VGVAPGVGV-APGI---GP---GGVAAAAK-SAAKVAAKA---QLRAAAGLGAGIPGLGV 536 Query: 5409 PQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGAT 5468 G+ PG + G V + G G + G +A + G V G LG Sbjct: 537 ---GVGVPGLGVGAGVPGLGVGAGVPGFGA---VPGALAAAKAAKY---GAAVPGVLGGL 587 Query: 5469 GEIKGPTVGGGLPGIG 5484 G + G + GG+ G G Sbjct: 588 GALGGVGIPGGVVGAG 603 Score = 38.1 bits (87), Expect = 0.26 Identities = 84/358 (23%), Positives = 125/358 (34%), Gaps = 68/358 (18%) Query: 5238 MPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKV 5297 +P G+PGV + G G V P + G V PGV P Sbjct: 336 VPGAGVPGVGVPGAGIPVV------------PGAGIPGAAV----PGVVSPEAAAKAAAK 379 Query: 5298 S---GPDLDLNLKGPSLKGDLDASVPSMKVHAPGL----NLSGVGGKMQVGGDGVKVPGI 5350 + G + + G G P V G+ + GVGG VGG VPG+ Sbjct: 380 AAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGG----VPGV 435 Query: 5351 DATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQ 5410 + + A + + G G P V V AP + L G P Sbjct: 436 GISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGV-APGVGLAPGVGVA-------PG 487 Query: 5411 FGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGE 5470 G++ PG + P + GPG G +A + +++ + G Sbjct: 488 VGVA-PGVGV-----APGI-----GPG------GVAAAAKSAAKVAAKAQLRAAAGLGAG 530 Query: 5471 IKGPTVGGGLPGIGV----------QGLEGNLQMPG----IKSSGCDVNLPGVNVKLPTG 5516 I G VG G+PG+GV G+ G +PG K++ +PGV L G Sbjct: 531 IPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGL--G 588 Query: 5517 QISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSG 5574 + G I GG+ G+ AA + K F + G+ + G + G + G Sbjct: 589 ALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGG 646 >gi|126352700 elastin isoform b precursor [Homo sapiens] Length = 677 Score = 57.0 bits (136), Expect = 5e-07 Identities = 123/469 (26%), Positives = 163/469 (34%), Gaps = 63/469 (13%) Query: 5210 GDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPS---LEGDL 5266 G VP VG G P+ +P +G+PGV GG A+ P L G Sbjct: 103 GGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGV--YPGGVLPGARFPGVGVLPGVP 160 Query: 5267 RGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKV-- 5324 G VK + P V G +P V G L +K P L G + K+ Sbjct: 161 TGAGVKPKAPGVG--GAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPY 218 Query: 5325 -HAPGLNLSGVGGK------MQVGGDGVKVPGIDATTKLNVGA----PDVTLRG-PSLQG 5372 + PG ++G GK VG A K GA P V G P + G Sbjct: 219 GYGPG-GVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG 277 Query: 5373 DLAVSGDIK---CPKVSVGAPDLSLEASEGSIKLPKMKLPQFG---ISTPGSDLHVNAKG 5426 + G I P + A + A G+ P FG + PG+ V G Sbjct: 278 AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAG--VPGVG 335 Query: 5427 PQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVG--------- 5477 +G PG + P + P V K G G VG Sbjct: 336 VPGAGIPVVPGAGI----PGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGA 391 Query: 5478 GGLP--GIGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFH 5535 GG P G+GV G+ G +PG+ +PGV + P Q + K G G Sbjct: 392 GGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGIS-PEAQ-AAAAAKAAKYGLVPGV- 448 Query: 5536 GAAPDISVKGPAFNMASPESDFGINL-KGPKIKGGADVSGGVS-APDISLGEGHLSVKGS 5593 G AP + V P +A G+ L G + G V+ GV AP I G + K + Sbjct: 449 GVAPGVGV-APGVGVAP-----GVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSA 502 Query: 5594 GGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQAPGLSV 5642 Q+ +A L G G V GV G +G PGL V Sbjct: 503 AKVAAKAQLRAAAGL-------GAGIPGLGVGVGVPGLGVGAGVPGLGV 544 Score = 38.1 bits (87), Expect = 0.26 Identities = 88/316 (27%), Positives = 126/316 (39%), Gaps = 55/316 (17%) Query: 5185 PSFG---ISAPQVSIPDVNVNLKGPKIKGDVPSVGLEGPDVD-LQGPEAKIKFP----KF 5236 P FG + P +P V V G + VP G+ G V + PEA K K+ Sbjct: 317 PGFGPGVVGVPGAGVPGVGVPGAGIPV---VPGAGIPGAAVPGVVSPEAAAKAAAKAAKY 373 Query: 5237 -SMPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVD-LPSVNLSM 5294 + P +G+ G+ G GA G G V + G PGV +P V + Sbjct: 374 GARPGVGVGGIPTYGVGA----------GGFPGFGVGVGGIPGVAGVPGVGGVPGVG-GV 422 Query: 5295 PKVS-GPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLS-GVGGKMQVG---GDGVKVPG 5349 P V P+ + K L VP + V APG+ ++ GVG VG G GV PG Sbjct: 423 PGVGISPEAQAAAAAKAAKYGL---VPGVGV-APGVGVAPGVGVAPGVGLAPGVGV-APG 477 Query: 5350 IDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEG-SIKLPKMKL 5408 + + V AP + GP G +A + KV+ A L A+ G +P + + Sbjct: 478 VGVAPGVGV-APGI---GP---GGVAAAAK-SAAKVAAKA---QLRAAAGLGAGIPGLGV 526 Query: 5409 PQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGAT 5468 G+ PG + G V + G G + G +A + G V G LG Sbjct: 527 ---GVGVPGLGVGAGVPGLGVGAGVPGFGA---VPGALAAAKAAKY---GAAVPGVLGGL 577 Query: 5469 GEIKGPTVGGGLPGIG 5484 G + G + GG+ G G Sbjct: 578 GALGGVGIPGGVVGAG 593 Score = 38.1 bits (87), Expect = 0.26 Identities = 84/358 (23%), Positives = 125/358 (34%), Gaps = 68/358 (18%) Query: 5238 MPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKV 5297 +P G+PGV + G G V P + G V PGV P Sbjct: 326 VPGAGVPGVGVPGAGIPVV------------PGAGIPGAAV----PGVVSPEAAAKAAAK 369 Query: 5298 S---GPDLDLNLKGPSLKGDLDASVPSMKVHAPGL----NLSGVGGKMQVGGDGVKVPGI 5350 + G + + G G P V G+ + GVGG VGG VPG+ Sbjct: 370 AAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGG----VPGV 425 Query: 5351 DATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQ 5410 + + A + + G G P V V AP + L G P Sbjct: 426 GISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGV-APGVGLAPGVGVA-------PG 477 Query: 5411 FGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGE 5470 G++ PG + P + GPG G +A + +++ + G Sbjct: 478 VGVA-PGVGV-----APGI-----GPG------GVAAAAKSAAKVAAKAQLRAAAGLGAG 520 Query: 5471 IKGPTVGGGLPGIGV----------QGLEGNLQMPG----IKSSGCDVNLPGVNVKLPTG 5516 I G VG G+PG+GV G+ G +PG K++ +PGV L G Sbjct: 521 IPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGL--G 578 Query: 5517 QISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSG 5574 + G I GG+ G+ AA + K F + G+ + G + G + G Sbjct: 579 ALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGG 636 >gi|126352440 elastin isoform a precursor [Homo sapiens] Length = 724 Score = 56.6 bits (135), Expect = 7e-07 Identities = 123/485 (25%), Positives = 165/485 (34%), Gaps = 76/485 (15%) Query: 5210 GDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPS---LEGDL 5266 G VP VG G P+ +P +G+PGV GG A+ P L G Sbjct: 113 GGVPGVGGLGVSAGAVVPQPGAGVKPGKVPGVGLPGV--YPGGVLPGARFPGVGVLPGVP 170 Query: 5267 RGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKV-- 5324 G VK + P V G +P V G L +K P L G + K+ Sbjct: 171 TGAGVKPKAPGVG--GAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPY 228 Query: 5325 -HAPGLNLSGVGGK------MQVGGDGVKVPGIDATTKLNVGA----PDVTLRG-PSLQG 5372 + PG ++G GK VG A K GA P V G P + G Sbjct: 229 GYGPG-GVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPGVPG 287 Query: 5373 DLAVSGDIK---CPKVSVGAPDLSLEASEGSIKLPKMKLPQFG---ISTPGSDLHVNAKG 5426 + G I P + A + A G+ P FG + PG+ V G Sbjct: 288 AIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAG--VPGVG 345 Query: 5427 PQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVG--------- 5477 +G PG + P + P V K G G VG Sbjct: 346 VPGAGIPVVPGAGI----PGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGA 401 Query: 5478 GGLP--GIGVQGLEGNLQMPGIKSSGCDVNLPGVNV-------------KLPTGQISGPE 5522 GG P G+GV G+ G +PG+ +PGV + K G + Sbjct: 402 GGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAA 461 Query: 5523 IKGGLKGSEVGF---HGAAPDISVKGPAFNMASPESDFGINL-KGPKIKGGADVSGGVS- 5577 K K ++ G G AP + V P +A G+ L G + G V+ GV Sbjct: 462 AKAAAKAAQFGLVPGVGVAPGVGV-APGVGVAP-----GVGLAPGVGVAPGVGVAPGVGV 515 Query: 5578 APDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQA 5637 AP I G + K + Q+ +A L G G V GV G +G Sbjct: 516 APGIGPGGVAAAAKSAAKVAAKAQLRAAAGL-------GAGIPGLGVGVGVPGLGVGAGV 568 Query: 5638 PGLSV 5642 PGL V Sbjct: 569 PGLGV 573 Score = 42.4 bits (98), Expect = 0.014 Identities = 84/371 (22%), Positives = 131/371 (35%), Gaps = 75/371 (20%) Query: 5238 MPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKV 5297 +P G+PGV + G G V PG +P ++P V Sbjct: 336 VPGAGVPGVGVPGAGIPVV--------------------------PGAGIPGA--AVPGV 367 Query: 5298 SGPDLDLNLKGPSLK-----GDLDASVPSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDA 5352 P+ + K G +P+ V A G GVG VGG +PG+ Sbjct: 368 VSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVG----VGG----IPGVAG 419 Query: 5353 TTKLNVGAPDVT-LRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKL--- 5408 + G P V + G + + + K K VG P + A++ + K + L Sbjct: 420 VPGVG-GVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTP--AAAAAKAAAKAAQFGLVPG 476 Query: 5409 ----PQFGIS-----TPGSDLHVNAKGPQVSGELKGPGV--DVNLKGPRISAPNVDFNLE 5457 P G++ PG L G G GV + G +A + Sbjct: 477 VGVAPGVGVAPGVGVAPGVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAAKSAAKVAA 536 Query: 5458 GPKVKGSLGATGEIKGPTVGGGLPGIGV----------QGLEGNLQMPG----IKSSGCD 5503 +++ + G I G VG G+PG+GV G+ G +PG K++ Sbjct: 537 KAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYG 596 Query: 5504 VNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKG 5563 +PGV L G + G I GG+ G+ AA + K F + G+ + G Sbjct: 597 AAVPGVLGGL--GALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGG 654 Query: 5564 PKIKGGADVSG 5574 + G + G Sbjct: 655 LGVPGVGGLGG 665 >gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo sapiens] Length = 1424 Score = 56.6 bits (135), Expect = 7e-07 Identities = 141/553 (25%), Positives = 191/553 (34%), Gaps = 92/553 (16%) Query: 5156 EGDLKGPKVQANLGAPDI-NIEGLDAKVKTPSFGISAPQVSIPDVNVNLKG-PKIKGDVP 5213 +G+ P + LG P I GL + P+ D+ ++ KG P + G Sbjct: 129 KGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPA--------KEEDIELDAKGDPGLPGAPG 180 Query: 5214 SVGLEGPD-----VDLQGPEAKIKFPKFSMPK-------------IGIPGVK-MEGGGAE 5254 GL GP V GP FP P+ G GVK + G Sbjct: 181 PQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGP 240 Query: 5255 VHAQLPSLEGDLRGPDVKLEGPDVSLKG-PGVDLPS--VNLSMPKVSGPDLDLNLKGPSL 5311 + +L G D+K E D G PG PS S G D L+G Sbjct: 241 PGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPG 300 Query: 5312 KGDLDASVPSMKVHA----PGL-NLSGVGG-KMQVGGDGVKVPGIDATTKLNVGAPDVTL 5365 K + S V PGL G+ G K +G G + P T G + T Sbjct: 301 KDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKG-DEGTP 359 Query: 5366 RGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAK 5425 P +G G P V G+P S G+ P +K + PG D Sbjct: 360 GPPGPRGARGPQGPSGPPGVP-GSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPG 418 Query: 5426 GPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEI---KGPTVGGGLPG 5482 P +G PG+ P G G G+I KGP GLPG Sbjct: 419 SPGCAGS---PGL--------------------PGSPGPPGPPGDIVFRKGPPGDHGLPG 455 Query: 5483 I----GVQGLEGNLQMPGIKSSGCDV-----NLPGVNVKLPTGQISGPEIKGGLKGSE-- 5531 G+ G++G PG+ + C LPG+ I G + GLKGS Sbjct: 456 YLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGS 515 Query: 5532 ---------VGFHGAAPDISVKGPAFNMASPESDFGI----NLKG-PKIKGGADVSGGVS 5577 GF GA D +KG PE G+ L+G P KG + G Sbjct: 516 PGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG 575 Query: 5578 APDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQA 5637 + +G L++ G G+ P + G GP+ E G++G Q A Sbjct: 576 VKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA 635 Query: 5638 PG-LSVSGPQGHL 5649 PG +GP+G L Sbjct: 636 PGPPGEAGPRGEL 648 Score = 48.9 bits (115), Expect = 1e-04 Identities = 117/478 (24%), Positives = 164/478 (34%), Gaps = 96/478 (20%) Query: 5203 LKGPKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSL 5262 L GP + +P +G GP GP+ FP + +G PG KM G LP Sbjct: 687 LPGPDGEPGIPGIGFPGPP----GPKGDQGFPG-TKGSLGCPG-KMGEPGLPGKPGLPGA 740 Query: 5263 EGDLRGPDVKLEGPDVSLKGPG----------VDLPSVNLSMPKVSGPDLDLNLKGPSLK 5312 +G+ P V + G + PG + LP +P + G + L GP + Sbjct: 741 KGE---PAVAMPGGPGTPGFPGERGNSGEHGEIGLPG----LPGLPGTPGNEGLDGP--R 791 Query: 5313 GDLDASVPSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQG 5372 GD P + PG + G G + PG++ L+G QG Sbjct: 792 GDPGQPGPPGEQGPPGRCIEGPRGAQGL-------PGLNG------------LKGQ--QG 830 Query: 5373 DLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGE 5432 +G PK G P L G +PG H GP G+ Sbjct: 831 RRGKTG----PKGDPGIPGLDRSGFPGET------------GSPGIPGHQGEMGPL--GQ 872 Query: 5433 LKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNL 5492 PG + + GP P D + G++G G P G G+ G++G Sbjct: 873 RGYPG-NPGILGP----PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQR 927 Query: 5493 QMPGIKSSGCDVNLPGVN-VKLPTGQISGPEIKG-----GLKGSE--VGFHGAAPDISVK 5544 PG K D PG + + G P +KG G KG+ G G + Sbjct: 928 GTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLP 987 Query: 5545 GPAFNMASPESDFGI--NLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQV 5602 GPA P D G N P ++G G + P G L G G P + Sbjct: 988 GPA-GPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGR---PGL 1043 Query: 5603 SSALNLDTSKFAGGLHFS------GPKVEGGVKG-----GQIGLQAP--GLSVSGPQG 5647 L K G GP + G+ G G++G P L +GP+G Sbjct: 1044 PGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEG 1101 Score = 42.0 bits (97), Expect = 0.018 Identities = 127/484 (26%), Positives = 169/484 (34%), Gaps = 103/484 (21%) Query: 5206 PKIKGDVPSVGLEGPDVDLQGP-EAKIKFPKFSMPKIGIPGVKMEGG--GAEVHAQLPSL 5262 P +KG + G +G D P ++I + G PG+K G G + + +P + Sbjct: 921 PGVKGQRGTPGAKGEQGDKGNPGPSEISHV---IGDKGEPGLKGFAGNPGEKGNRGVPGM 977 Query: 5263 EG--DLRGPDVKLEGPDVSLKGPGVDLPSV-NLSMPKVSG-PDLDLNLKGPSLKGDLDAS 5318 G L+G L GP GP DL S N P + G P N+ P KG Sbjct: 978 PGLKGLKG----LPGP-AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTL 1032 Query: 5319 VPSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSG 5378 + PGL G+ G G+ PG T+ G P T P L GD+ G Sbjct: 1033 GFPGRAGRPGL--PGIHGLQGDKGE----PGYSEGTR--PGPPGPT-GDPGLPGDMGKKG 1083 Query: 5379 DIKCPKV--------------SVGAP----------DLSLEASEGSIKLPKMKLPQFGIS 5414 ++ P S G+P DL + +G + P ++ P Sbjct: 1084 EMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPG 1143 Query: 5415 TPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGP 5474 PGS + +G Q + GP + G + P N KG GA G Sbjct: 1144 FPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPG----- 1198 Query: 5475 TVGGGLPG-IGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKG-------- 5525 GLPG G G G GI+ LPG + TG P +G Sbjct: 1199 --FPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPP 1256 Query: 5526 GLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGE 5585 G GS V I +KG +M P GP KG +G + P Sbjct: 1257 GPPGSHV--------IGIKGDKGSMGHP---------GP--KGPPGTAGDMGPP------ 1291 Query: 5586 GHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKG--GQIGLQAPGLSVS 5643 G L G+ G GP+ F G F G K E G G G IG P + Sbjct: 1292 GRLGAPGTPG-LPGPRGDPG-------FQG---FPGVKGEKGNPGFLGSIGPPGP-IGPK 1339 Query: 5644 GPQG 5647 GP G Sbjct: 1340 GPPG 1343 Score = 41.6 bits (96), Expect = 0.024 Identities = 92/347 (26%), Positives = 129/347 (37%), Gaps = 50/347 (14%) Query: 5200 NVNLKG-PKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGG--GAEVH 5256 N L G P G GL+G + PE ++ P G PG++ + G G + Sbjct: 518 NTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVP-------GDPGLRGQPGRKGLDGI 570 Query: 5257 AQLPSLEGDLRGPDVKL--------EGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKG 5308 P ++G L GP +L +GP PG P+ P GP + L+G Sbjct: 571 PGTPGVKG-LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGY-GPQGEPGLQG 628 Query: 5309 PSLKGDLDASVPSMKVHAPGL-NLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRG 5367 VP APG +G G++ V VPG G P Sbjct: 629 TQ-------GVPG----APGPPGEAGPRGELSVS---TPVPGPPGPP----GPPG----H 666 Query: 5368 PSLQGDLAVSGDI-KCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKG 5426 P QG + G + KC + PD E I P P+ PG+ + G Sbjct: 667 PGPQGPPGIPGSLGKCGDPGLPGPDG--EPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPG 724 Query: 5427 PQVSGELKG-PGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGI-G 5484 L G PG+ P ++ P P +G+ G GEI P + G LPG G Sbjct: 725 KMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPG-LPGTPG 783 Query: 5485 VQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSE 5531 +GL+G PG + PG ++ P G P + GLKG + Sbjct: 784 NEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGL-NGLKGQQ 829 Score = 36.2 bits (82), Expect = 0.99 Identities = 91/341 (26%), Positives = 116/341 (34%), Gaps = 48/341 (14%) Query: 5241 IGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLS------M 5294 +G+PG G++ P L G L P + KG + L + Sbjct: 120 VGVPGCS----GSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGL 175 Query: 5295 PKVSGPDLDLNLKGP-SLKGDLDASVPSMKVHAPG-LNLSGVGGKM------QVGGDGVK 5346 P GP L GP G + P PG + G G M G GVK Sbjct: 176 PGAPGPQ---GLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVK 232 Query: 5347 ----VPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIK 5402 PG T + + PD +GD G+ P S G P S + +G+ Sbjct: 233 GLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPS-GLPGESYGSEKGAPG 291 Query: 5403 LPKMKLPQFGISTPGSDLHVNAKG----PQVSGE--LKGPGVDVNLKGPRISAPNVDFNL 5456 P ++ PG KG P + GE +KG D+ G R D Sbjct: 292 DPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQ 351 Query: 5457 EG--------PKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPG 5508 E P +G+ G G GP G PG GL G PG+K S + PG Sbjct: 352 EKGDEGTPGPPGPRGARGPQGP-SGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG 410 Query: 5509 VNVKLPTGQISGPEIKG--GLKGSEVGFHGAAPDISV-KGP 5546 K G P G GL GS G G DI KGP Sbjct: 411 ---KDAMGTPGSPGCAGSPGLPGSP-GPPGPPGDIVFRKGP 447 Score = 35.0 bits (79), Expect = 2.2 Identities = 58/220 (26%), Positives = 83/220 (37%), Gaps = 41/220 (18%) Query: 267 LGGRGGVQVPAVDISSSLGGRAVEVQGPSLESGDHGKIKFPTMKVPKFGVSTGREGQTPK 326 LG G +P D + G + GP GD G FP K S G G+ + Sbjct: 679 LGKCGDPGLPGPDGEPGIPG--IGFPGPPGPKGDQG---FPGTKG-----SLGCPGKMGE 728 Query: 327 AGLRVSAPEVSVGHKGGKPGLTIQAPQLEVSVPSANIEGLEGKLKGPQITGPSLE-GDLG 385 GL GKPGL + V++P G G P G S E G++G Sbjct: 729 PGLP------------GKPGLPGAKGEPAVAMP-----GGPGTPGFPGERGNSGEHGEIG 771 Query: 386 LKGAK----PQGHIGVDASAPQIGGSITGPSVEVQAPDIDVQGPGSKLNVPKMKVPKFSV 441 L G G+ G+D P+ GP E P ++GP +P + Sbjct: 772 LPGLPGLPGTPGNEGLDG--PRGDPGQPGPPGEQGPPGRCIEGPRGAQGLP-------GL 822 Query: 442 SGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLEG 481 +G KG++ T P G+ +PG+ E + G+ G Sbjct: 823 NGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPG 862 Score = 34.3 bits (77), Expect = 3.8 Identities = 116/441 (26%), Positives = 153/441 (34%), Gaps = 65/441 (14%) Query: 5156 EGDLKG-PKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPS 5214 E L+G P N+G P G K T F A + +P ++ L+G K + Sbjct: 1007 EPGLRGIPGSMGNMGMP-----GSKGKRGTLGFPGRAGRPGLPGIH-GLQGDKGEPGYSE 1060 Query: 5215 VGLEGP-----DVDLQGPEAKIKFPKFSMPKIGIPGVKMEGG--GAEVHAQLPSLEGDLR 5267 GP D L G K K M + G PG G GA P L G Sbjct: 1061 GTRPGPPGPTGDPGLPGDMGK----KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK-P 1115 Query: 5268 GP--DVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVH 5325 GP D+ +G L PG+ P P GP + ++G + + P+ + Sbjct: 1116 GPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP---MGIRGDQGRDGIPG--PAGEKG 1170 Query: 5326 APGLNLSGVGGKMQVGGDGVK----VPGIDATTKLNVGAPDVTLRGPS----LQGDLAVS 5377 GL + G + G G K PG D RGP+ G + Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230 Query: 5378 GDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQ----FGIS-TPGSDLHVNAKGPQVSGE 5432 G I + P S GS P P GI GS H KGP + Sbjct: 1231 GAIIPGQTGNRGPP----GSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG 1286 Query: 5433 LKGPGVDVNLKG-PRISAPNVDFNLEG-PKVKGSLGATGEI-----KGPTVGGGLPGIGV 5485 GP + G P + P D +G P VKG G G + GP G PG V Sbjct: 1287 DMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG--V 1344 Query: 5486 QGLEGNLQMPGIKSSGCDVNLPG-------VNVKLPTGQIS--GPEIKGGLKGSEVGFHG 5536 +G G L++ + S PG P G + GP K G K + G G Sbjct: 1345 RGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPG-KDGKPGTPG 1403 Query: 5537 AAPDISVKGPAFNMASPESDF 5557 A + KG + PES F Sbjct: 1404 PAGE---KGNKGSKGEPESLF 1421 Score = 33.9 bits (76), Expect = 4.9 Identities = 71/288 (24%), Positives = 100/288 (34%), Gaps = 60/288 (20%) Query: 2535 PKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPKISMPDFDLHLKG---- 2590 PK ++ +SG K D +GP G P P P P + L+G Sbjct: 582 PKGELALSGEKGD--------QGPPGDPGSPGSPGPAGPAGPPGYG-PQGEPGLQGTQGV 632 Query: 2591 PKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKMPKVKMPKFSMPG 2650 P G + P+ E + P GP P G QGP PG Sbjct: 633 PGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHP--GPQGP----------------PG 674 Query: 2651 FKGE-GPDGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKLKGPKFKMPEMNIKAP-KIS 2708 G G GD LP D + P + GP GP+G P K ++ P K+ Sbjct: 675 IPGSLGKCGDPGLPGPDGEPGIPGIGFPGPP----GPKGDQGFPGTKG---SLGCPGKMG 727 Query: 2709 MPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPK 2768 P + P KG+ V++P G P + + HG + Sbjct: 728 EPGLPGKPGLPGAKGEPAVAMPGGPGT----------PGFPGERGNSGEHG--------E 769 Query: 2769 IKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGPEG 2816 I +P +PG G + ++ P+ D GP + P IEGP G Sbjct: 770 IGLP--GLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRG 815 >gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo sapiens] Length = 1494 Score = 56.6 bits (135), Expect = 7e-07 Identities = 141/553 (25%), Positives = 191/553 (34%), Gaps = 92/553 (16%) Query: 5156 EGDLKGPKVQANLGAPDI-NIEGLDAKVKTPSFGISAPQVSIPDVNVNLKG-PKIKGDVP 5213 +G+ P + LG P I GL + P+ D+ ++ KG P + G Sbjct: 129 KGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPA--------KEEDIELDAKGDPGLPGAPG 180 Query: 5214 SVGLEGPD-----VDLQGPEAKIKFPKFSMPK-------------IGIPGVK-MEGGGAE 5254 GL GP V GP FP P+ G GVK + G Sbjct: 181 PQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGP 240 Query: 5255 VHAQLPSLEGDLRGPDVKLEGPDVSLKG-PGVDLPS--VNLSMPKVSGPDLDLNLKGPSL 5311 + +L G D+K E D G PG PS S G D L+G Sbjct: 241 PGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPG 300 Query: 5312 KGDLDASVPSMKVHA----PGL-NLSGVGG-KMQVGGDGVKVPGIDATTKLNVGAPDVTL 5365 K + S V PGL G+ G K +G G + P T G + T Sbjct: 301 KDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKG-DEGTP 359 Query: 5366 RGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAK 5425 P +G G P V G+P S G+ P +K + PG D Sbjct: 360 GPPGPRGARGPQGPSGPPGVP-GSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPG 418 Query: 5426 GPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEI---KGPTVGGGLPG 5482 P +G PG+ P G G G+I KGP GLPG Sbjct: 419 SPGCAGS---PGL--------------------PGSPGPPGPPGDIVFRKGPPGDHGLPG 455 Query: 5483 I----GVQGLEGNLQMPGIKSSGCDV-----NLPGVNVKLPTGQISGPEIKGGLKGSE-- 5531 G+ G++G PG+ + C LPG+ I G + GLKGS Sbjct: 456 YLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGS 515 Query: 5532 ---------VGFHGAAPDISVKGPAFNMASPESDFGI----NLKG-PKIKGGADVSGGVS 5577 GF GA D +KG PE G+ L+G P KG + G Sbjct: 516 PGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG 575 Query: 5578 APDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQA 5637 + +G L++ G G+ P + G GP+ E G++G Q A Sbjct: 576 VKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA 635 Query: 5638 PG-LSVSGPQGHL 5649 PG +GP+G L Sbjct: 636 PGPPGEAGPRGEL 648 Score = 48.9 bits (115), Expect = 1e-04 Identities = 117/478 (24%), Positives = 164/478 (34%), Gaps = 96/478 (20%) Query: 5203 LKGPKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSL 5262 L GP + +P +G GP GP+ FP + +G PG KM G LP Sbjct: 687 LPGPDGEPGIPGIGFPGPP----GPKGDQGFPG-TKGSLGCPG-KMGEPGLPGKPGLPGA 740 Query: 5263 EGDLRGPDVKLEGPDVSLKGPG----------VDLPSVNLSMPKVSGPDLDLNLKGPSLK 5312 +G+ P V + G + PG + LP +P + G + L GP + Sbjct: 741 KGE---PAVAMPGGPGTPGFPGERGNSGEHGEIGLPG----LPGLPGTPGNEGLDGP--R 791 Query: 5313 GDLDASVPSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQG 5372 GD P + PG + G G + PG++ L+G QG Sbjct: 792 GDPGQPGPPGEQGPPGRCIEGPRGAQGL-------PGLNG------------LKGQ--QG 830 Query: 5373 DLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGE 5432 +G PK G P L G +PG H GP G+ Sbjct: 831 RRGKTG----PKGDPGIPGLDRSGFPGET------------GSPGIPGHQGEMGPL--GQ 872 Query: 5433 LKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNL 5492 PG + + GP P D + G++G G P G G+ G++G Sbjct: 873 RGYPG-NPGILGP----PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQR 927 Query: 5493 QMPGIKSSGCDVNLPGVN-VKLPTGQISGPEIKG-----GLKGSE--VGFHGAAPDISVK 5544 PG K D PG + + G P +KG G KG+ G G + Sbjct: 928 GTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLP 987 Query: 5545 GPAFNMASPESDFGI--NLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQV 5602 GPA P D G N P ++G G + P G L G G P + Sbjct: 988 GPA-GPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGR---PGL 1043 Query: 5603 SSALNLDTSKFAGGLHFS------GPKVEGGVKG-----GQIGLQAP--GLSVSGPQG 5647 L K G GP + G+ G G++G P L +GP+G Sbjct: 1044 PGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEG 1101 Score = 42.0 bits (97), Expect = 0.018 Identities = 127/484 (26%), Positives = 169/484 (34%), Gaps = 103/484 (21%) Query: 5206 PKIKGDVPSVGLEGPDVDLQGP-EAKIKFPKFSMPKIGIPGVKMEGG--GAEVHAQLPSL 5262 P +KG + G +G D P ++I + G PG+K G G + + +P + Sbjct: 921 PGVKGQRGTPGAKGEQGDKGNPGPSEISHV---IGDKGEPGLKGFAGNPGEKGNRGVPGM 977 Query: 5263 EG--DLRGPDVKLEGPDVSLKGPGVDLPSV-NLSMPKVSG-PDLDLNLKGPSLKGDLDAS 5318 G L+G L GP GP DL S N P + G P N+ P KG Sbjct: 978 PGLKGLKG----LPGP-AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTL 1032 Query: 5319 VPSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSG 5378 + PGL G+ G G+ PG T+ G P T P L GD+ G Sbjct: 1033 GFPGRAGRPGL--PGIHGLQGDKGE----PGYSEGTR--PGPPGPT-GDPGLPGDMGKKG 1083 Query: 5379 DIKCPKV--------------SVGAP----------DLSLEASEGSIKLPKMKLPQFGIS 5414 ++ P S G+P DL + +G + P ++ P Sbjct: 1084 EMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPG 1143 Query: 5415 TPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGP 5474 PGS + +G Q + GP + G + P N KG GA G Sbjct: 1144 FPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPG----- 1198 Query: 5475 TVGGGLPG-IGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKG-------- 5525 GLPG G G G GI+ LPG + TG P +G Sbjct: 1199 --FPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPP 1256 Query: 5526 GLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGE 5585 G GS V I +KG +M P GP KG +G + P Sbjct: 1257 GPPGSHV--------IGIKGDKGSMGHP---------GP--KGPPGTAGDMGPP------ 1291 Query: 5586 GHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKG--GQIGLQAPGLSVS 5643 G L G+ G GP+ F G F G K E G G G IG P + Sbjct: 1292 GRLGAPGTPG-LPGPRGDPG-------FQG---FPGVKGEKGNPGFLGSIGPPGP-IGPK 1339 Query: 5644 GPQG 5647 GP G Sbjct: 1340 GPPG 1343 Score = 41.6 bits (96), Expect = 0.024 Identities = 92/347 (26%), Positives = 129/347 (37%), Gaps = 50/347 (14%) Query: 5200 NVNLKG-PKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGG--GAEVH 5256 N L G P G GL+G + PE ++ P G PG++ + G G + Sbjct: 518 NTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVP-------GDPGLRGQPGRKGLDGI 570 Query: 5257 AQLPSLEGDLRGPDVKL--------EGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKG 5308 P ++G L GP +L +GP PG P+ P GP + L+G Sbjct: 571 PGTPGVKG-LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGY-GPQGEPGLQG 628 Query: 5309 PSLKGDLDASVPSMKVHAPGL-NLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRG 5367 VP APG +G G++ V VPG G P Sbjct: 629 TQ-------GVPG----APGPPGEAGPRGELSVS---TPVPGPPGPP----GPPG----H 666 Query: 5368 PSLQGDLAVSGDI-KCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKG 5426 P QG + G + KC + PD E I P P+ PG+ + G Sbjct: 667 PGPQGPPGIPGSLGKCGDPGLPGPDG--EPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPG 724 Query: 5427 PQVSGELKG-PGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGI-G 5484 L G PG+ P ++ P P +G+ G GEI P + G LPG G Sbjct: 725 KMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPG-LPGTPG 783 Query: 5485 VQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSE 5531 +GL+G PG + PG ++ P G P + GLKG + Sbjct: 784 NEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGL-NGLKGQQ 829 Score = 36.2 bits (82), Expect = 0.99 Identities = 91/341 (26%), Positives = 116/341 (34%), Gaps = 48/341 (14%) Query: 5241 IGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLS------M 5294 +G+PG G++ P L G L P + KG + L + Sbjct: 120 VGVPGCS----GSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGL 175 Query: 5295 PKVSGPDLDLNLKGP-SLKGDLDASVPSMKVHAPG-LNLSGVGGKM------QVGGDGVK 5346 P GP L GP G + P PG + G G M G GVK Sbjct: 176 PGAPGPQ---GLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVK 232 Query: 5347 ----VPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIK 5402 PG T + + PD +GD G+ P S G P S + +G+ Sbjct: 233 GLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPS-GLPGESYGSEKGAPG 291 Query: 5403 LPKMKLPQFGISTPGSDLHVNAKG----PQVSGE--LKGPGVDVNLKGPRISAPNVDFNL 5456 P ++ PG KG P + GE +KG D+ G R D Sbjct: 292 DPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQ 351 Query: 5457 EG--------PKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPG 5508 E P +G+ G G GP G PG GL G PG+K S + PG Sbjct: 352 EKGDEGTPGPPGPRGARGPQGP-SGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG 410 Query: 5509 VNVKLPTGQISGPEIKG--GLKGSEVGFHGAAPDISV-KGP 5546 K G P G GL GS G G DI KGP Sbjct: 411 ---KDAMGTPGSPGCAGSPGLPGSP-GPPGPPGDIVFRKGP 447 Score = 35.8 bits (81), Expect = 1.3 Identities = 123/475 (25%), Positives = 164/475 (34%), Gaps = 73/475 (15%) Query: 5156 EGDLKG-PKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPS 5214 E L+G P N+G P G K T F A + +P ++ L+G K + Sbjct: 1007 EPGLRGIPGSMGNMGMP-----GSKGKRGTLGFPGRAGRPGLPGIH-GLQGDKGEPGYSE 1060 Query: 5215 VGLEGP-----DVDLQGPEAKIKFPKFSMPKIGIPGVKMEGG--GAEVHAQLPSLEGDLR 5267 GP D L G K K M + G PG G GA P L G Sbjct: 1061 GTRPGPPGPTGDPGLPGDMGK----KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK-P 1115 Query: 5268 GP--DVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVH 5325 GP D+ +G L PG+ P P GP + ++G + + P+ + Sbjct: 1116 GPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP---MGIRGDQGRDGIPG--PAGEKG 1170 Query: 5326 APGLNLSGVGGKMQVGGDGVK----VPGIDATTKLNVGAPDVTLRGPS----LQGDLAVS 5377 GL + G + G G K PG D RGP+ G + Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230 Query: 5378 GDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQ----FGIS-TPGSDLHVNAKGPQVSGE 5432 G I + P S GS P P GI GS H KGP + Sbjct: 1231 GAIIPGQTGNRGPP----GSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG 1286 Query: 5433 LKGPGVDVNLKG-PRISAPNVDFNLEG-PKVKGSLGATGEI-----KGPTVGGGLPGIGV 5485 GP + G P + P D +G P VKG G G + GP G PG V Sbjct: 1287 DMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG--V 1344 Query: 5486 QGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAPDISVKG 5545 +G G L++ + S PG P G P ++G E G G ++ G Sbjct: 1345 RGDPGTLKIISLPGS------PG-----PPGTPGEPGMQG-----EPGPPGPPGNL---G 1385 Query: 5546 PAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGP 5600 P P D GP + G S G P S +G +KG G+ P Sbjct: 1386 PCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGS--DGLPGLKGKRGDSGSP 1438 Score = 35.0 bits (79), Expect = 2.2 Identities = 58/220 (26%), Positives = 83/220 (37%), Gaps = 41/220 (18%) Query: 267 LGGRGGVQVPAVDISSSLGGRAVEVQGPSLESGDHGKIKFPTMKVPKFGVSTGREGQTPK 326 LG G +P D + G + GP GD G FP K S G G+ + Sbjct: 679 LGKCGDPGLPGPDGEPGIPG--IGFPGPPGPKGDQG---FPGTKG-----SLGCPGKMGE 728 Query: 327 AGLRVSAPEVSVGHKGGKPGLTIQAPQLEVSVPSANIEGLEGKLKGPQITGPSLE-GDLG 385 GL GKPGL + V++P G G P G S E G++G Sbjct: 729 PGLP------------GKPGLPGAKGEPAVAMP-----GGPGTPGFPGERGNSGEHGEIG 771 Query: 386 LKGAK----PQGHIGVDASAPQIGGSITGPSVEVQAPDIDVQGPGSKLNVPKMKVPKFSV 441 L G G+ G+D P+ GP E P ++GP +P + Sbjct: 772 LPGLPGLPGTPGNEGLDG--PRGDPGQPGPPGEQGPPGRCIEGPRGAQGLP-------GL 822 Query: 442 SGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLEG 481 +G KG++ T P G+ +PG+ E + G+ G Sbjct: 823 NGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPG 862 Score = 33.9 bits (76), Expect = 4.9 Identities = 71/288 (24%), Positives = 100/288 (34%), Gaps = 60/288 (20%) Query: 2535 PKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPKISMPDFDLHLKG---- 2590 PK ++ +SG K D +GP G P P P P + L+G Sbjct: 582 PKGELALSGEKGD--------QGPPGDPGSPGSPGPAGPAGPPGYG-PQGEPGLQGTQGV 632 Query: 2591 PKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKMPKVKMPKFSMPG 2650 P G + P+ E + P GP P G QGP PG Sbjct: 633 PGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHP--GPQGP----------------PG 674 Query: 2651 FKGE-GPDGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKLKGPKFKMPEMNIKAP-KIS 2708 G G GD LP D + P + GP GP+G P K ++ P K+ Sbjct: 675 IPGSLGKCGDPGLPGPDGEPGIPGIGFPGPP----GPKGDQGFPGTKG---SLGCPGKMG 727 Query: 2709 MPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPK 2768 P + P KG+ V++P G P + + HG + Sbjct: 728 EPGLPGKPGLPGAKGEPAVAMPGGPGT----------PGFPGERGNSGEHG--------E 769 Query: 2769 IKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGPEG 2816 I +P +PG G + ++ P+ D GP + P IEGP G Sbjct: 770 IGLP--GLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRG 815 >gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo sapiens] Length = 1637 Score = 56.6 bits (135), Expect = 7e-07 Identities = 141/553 (25%), Positives = 191/553 (34%), Gaps = 92/553 (16%) Query: 5156 EGDLKGPKVQANLGAPDI-NIEGLDAKVKTPSFGISAPQVSIPDVNVNLKG-PKIKGDVP 5213 +G+ P + LG P I GL + P+ D+ ++ KG P + G Sbjct: 129 KGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPA--------KEEDIELDAKGDPGLPGAPG 180 Query: 5214 SVGLEGPD-----VDLQGPEAKIKFPKFSMPK-------------IGIPGVK-MEGGGAE 5254 GL GP V GP FP P+ G GVK + G Sbjct: 181 PQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGP 240 Query: 5255 VHAQLPSLEGDLRGPDVKLEGPDVSLKG-PGVDLPS--VNLSMPKVSGPDLDLNLKGPSL 5311 + +L G D+K E D G PG PS S G D L+G Sbjct: 241 PGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPG 300 Query: 5312 KGDLDASVPSMKVHA----PGL-NLSGVGG-KMQVGGDGVKVPGIDATTKLNVGAPDVTL 5365 K + S V PGL G+ G K +G G + P T G + T Sbjct: 301 KDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKG-DEGTP 359 Query: 5366 RGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAK 5425 P +G G P V G+P S G+ P +K + PG D Sbjct: 360 GPPGPRGARGPQGPSGPPGVP-GSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPG 418 Query: 5426 GPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEI---KGPTVGGGLPG 5482 P +G PG+ P G G G+I KGP GLPG Sbjct: 419 SPGCAGS---PGL--------------------PGSPGPPGPPGDIVFRKGPPGDHGLPG 455 Query: 5483 I----GVQGLEGNLQMPGIKSSGCDV-----NLPGVNVKLPTGQISGPEIKGGLKGSE-- 5531 G+ G++G PG+ + C LPG+ I G + GLKGS Sbjct: 456 YLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGS 515 Query: 5532 ---------VGFHGAAPDISVKGPAFNMASPESDFGI----NLKG-PKIKGGADVSGGVS 5577 GF GA D +KG PE G+ L+G P KG + G Sbjct: 516 PGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG 575 Query: 5578 APDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQA 5637 + +G L++ G G+ P + G GP+ E G++G Q A Sbjct: 576 VKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA 635 Query: 5638 PG-LSVSGPQGHL 5649 PG +GP+G L Sbjct: 636 PGPPGEAGPRGEL 648 Score = 48.9 bits (115), Expect = 1e-04 Identities = 117/478 (24%), Positives = 164/478 (34%), Gaps = 96/478 (20%) Query: 5203 LKGPKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSL 5262 L GP + +P +G GP GP+ FP + +G PG KM G LP Sbjct: 687 LPGPDGEPGIPGIGFPGPP----GPKGDQGFPG-TKGSLGCPG-KMGEPGLPGKPGLPGA 740 Query: 5263 EGDLRGPDVKLEGPDVSLKGPG----------VDLPSVNLSMPKVSGPDLDLNLKGPSLK 5312 +G+ P V + G + PG + LP +P + G + L GP + Sbjct: 741 KGE---PAVAMPGGPGTPGFPGERGNSGEHGEIGLPG----LPGLPGTPGNEGLDGP--R 791 Query: 5313 GDLDASVPSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQG 5372 GD P + PG + G G + PG++ L+G QG Sbjct: 792 GDPGQPGPPGEQGPPGRCIEGPRGAQGL-------PGLNG------------LKGQ--QG 830 Query: 5373 DLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGE 5432 +G PK G P L G +PG H GP G+ Sbjct: 831 RRGKTG----PKGDPGIPGLDRSGFPGET------------GSPGIPGHQGEMGPL--GQ 872 Query: 5433 LKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNL 5492 PG + + GP P D + G++G G P G G+ G++G Sbjct: 873 RGYPG-NPGILGP----PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQR 927 Query: 5493 QMPGIKSSGCDVNLPGVN-VKLPTGQISGPEIKG-----GLKGSE--VGFHGAAPDISVK 5544 PG K D PG + + G P +KG G KG+ G G + Sbjct: 928 GTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLP 987 Query: 5545 GPAFNMASPESDFGI--NLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQV 5602 GPA P D G N P ++G G + P G L G G P + Sbjct: 988 GPA-GPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGR---PGL 1043 Query: 5603 SSALNLDTSKFAGGLHFS------GPKVEGGVKG-----GQIGLQAP--GLSVSGPQG 5647 L K G GP + G+ G G++G P L +GP+G Sbjct: 1044 PGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEG 1101 Score = 42.0 bits (97), Expect = 0.018 Identities = 127/484 (26%), Positives = 169/484 (34%), Gaps = 103/484 (21%) Query: 5206 PKIKGDVPSVGLEGPDVDLQGP-EAKIKFPKFSMPKIGIPGVKMEGG--GAEVHAQLPSL 5262 P +KG + G +G D P ++I + G PG+K G G + + +P + Sbjct: 921 PGVKGQRGTPGAKGEQGDKGNPGPSEISHV---IGDKGEPGLKGFAGNPGEKGNRGVPGM 977 Query: 5263 EG--DLRGPDVKLEGPDVSLKGPGVDLPSV-NLSMPKVSG-PDLDLNLKGPSLKGDLDAS 5318 G L+G L GP GP DL S N P + G P N+ P KG Sbjct: 978 PGLKGLKG----LPGP-AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTL 1032 Query: 5319 VPSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSG 5378 + PGL G+ G G+ PG T+ G P T P L GD+ G Sbjct: 1033 GFPGRAGRPGL--PGIHGLQGDKGE----PGYSEGTR--PGPPGPT-GDPGLPGDMGKKG 1083 Query: 5379 DIKCPKV--------------SVGAP----------DLSLEASEGSIKLPKMKLPQFGIS 5414 ++ P S G+P DL + +G + P ++ P Sbjct: 1084 EMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPG 1143 Query: 5415 TPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGP 5474 PGS + +G Q + GP + G + P N KG GA G Sbjct: 1144 FPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPG----- 1198 Query: 5475 TVGGGLPG-IGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKG-------- 5525 GLPG G G G GI+ LPG + TG P +G Sbjct: 1199 --FPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPP 1256 Query: 5526 GLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGE 5585 G GS V I +KG +M P GP KG +G + P Sbjct: 1257 GPPGSHV--------IGIKGDKGSMGHP---------GP--KGPPGTAGDMGPP------ 1291 Query: 5586 GHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKG--GQIGLQAPGLSVS 5643 G L G+ G GP+ F G F G K E G G G IG P + Sbjct: 1292 GRLGAPGTPG-LPGPRGDPG-------FQG---FPGVKGEKGNPGFLGSIGPPGP-IGPK 1339 Query: 5644 GPQG 5647 GP G Sbjct: 1340 GPPG 1343 Score = 41.6 bits (96), Expect = 0.024 Identities = 92/347 (26%), Positives = 129/347 (37%), Gaps = 50/347 (14%) Query: 5200 NVNLKG-PKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGG--GAEVH 5256 N L G P G GL+G + PE ++ P G PG++ + G G + Sbjct: 518 NTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVP-------GDPGLRGQPGRKGLDGI 570 Query: 5257 AQLPSLEGDLRGPDVKL--------EGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKG 5308 P ++G L GP +L +GP PG P+ P GP + L+G Sbjct: 571 PGTPGVKG-LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGY-GPQGEPGLQG 628 Query: 5309 PSLKGDLDASVPSMKVHAPGL-NLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRG 5367 VP APG +G G++ V VPG G P Sbjct: 629 TQ-------GVPG----APGPPGEAGPRGELSVS---TPVPGPPGPP----GPPG----H 666 Query: 5368 PSLQGDLAVSGDI-KCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKG 5426 P QG + G + KC + PD E I P P+ PG+ + G Sbjct: 667 PGPQGPPGIPGSLGKCGDPGLPGPDG--EPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPG 724 Query: 5427 PQVSGELKG-PGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGI-G 5484 L G PG+ P ++ P P +G+ G GEI P + G LPG G Sbjct: 725 KMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPG-LPGTPG 783 Query: 5485 VQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSE 5531 +GL+G PG + PG ++ P G P + GLKG + Sbjct: 784 NEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGL-NGLKGQQ 829 Score = 36.2 bits (82), Expect = 0.99 Identities = 91/341 (26%), Positives = 116/341 (34%), Gaps = 48/341 (14%) Query: 5241 IGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLS------M 5294 +G+PG G++ P L G L P + KG + L + Sbjct: 120 VGVPGCS----GSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGL 175 Query: 5295 PKVSGPDLDLNLKGP-SLKGDLDASVPSMKVHAPG-LNLSGVGGKM------QVGGDGVK 5346 P GP L GP G + P PG + G G M G GVK Sbjct: 176 PGAPGPQ---GLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVK 232 Query: 5347 ----VPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIK 5402 PG T + + PD +GD G+ P S G P S + +G+ Sbjct: 233 GLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPS-GLPGESYGSEKGAPG 291 Query: 5403 LPKMKLPQFGISTPGSDLHVNAKG----PQVSGE--LKGPGVDVNLKGPRISAPNVDFNL 5456 P ++ PG KG P + GE +KG D+ G R D Sbjct: 292 DPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQ 351 Query: 5457 EG--------PKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPG 5508 E P +G+ G G GP G PG GL G PG+K S + PG Sbjct: 352 EKGDEGTPGPPGPRGARGPQGP-SGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG 410 Query: 5509 VNVKLPTGQISGPEIKG--GLKGSEVGFHGAAPDISV-KGP 5546 K G P G GL GS G G DI KGP Sbjct: 411 ---KDAMGTPGSPGCAGSPGLPGSP-GPPGPPGDIVFRKGP 447 Score = 35.8 bits (81), Expect = 1.3 Identities = 123/475 (25%), Positives = 164/475 (34%), Gaps = 73/475 (15%) Query: 5156 EGDLKG-PKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPS 5214 E L+G P N+G P G K T F A + +P ++ L+G K + Sbjct: 1007 EPGLRGIPGSMGNMGMP-----GSKGKRGTLGFPGRAGRPGLPGIH-GLQGDKGEPGYSE 1060 Query: 5215 VGLEGP-----DVDLQGPEAKIKFPKFSMPKIGIPGVKMEGG--GAEVHAQLPSLEGDLR 5267 GP D L G K K M + G PG G GA P L G Sbjct: 1061 GTRPGPPGPTGDPGLPGDMGK----KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK-P 1115 Query: 5268 GP--DVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVH 5325 GP D+ +G L PG+ P P GP + ++G + + P+ + Sbjct: 1116 GPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP---MGIRGDQGRDGIPG--PAGEKG 1170 Query: 5326 APGLNLSGVGGKMQVGGDGVK----VPGIDATTKLNVGAPDVTLRGPS----LQGDLAVS 5377 GL + G + G G K PG D RGP+ G + Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230 Query: 5378 GDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQ----FGIS-TPGSDLHVNAKGPQVSGE 5432 G I + P S GS P P GI GS H KGP + Sbjct: 1231 GAIIPGQTGNRGPP----GSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG 1286 Query: 5433 LKGPGVDVNLKG-PRISAPNVDFNLEG-PKVKGSLGATGEI-----KGPTVGGGLPGIGV 5485 GP + G P + P D +G P VKG G G + GP G PG V Sbjct: 1287 DMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG--V 1344 Query: 5486 QGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAPDISVKG 5545 +G G L++ + S PG P G P ++G E G G ++ G Sbjct: 1345 RGDPGTLKIISLPGS------PG-----PPGTPGEPGMQG-----EPGPPGPPGNL---G 1385 Query: 5546 PAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGP 5600 P P D GP + G S G P S +G +KG G+ P Sbjct: 1386 PCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGS--DGLPGLKGKRGDSGSP 1438 Score = 35.0 bits (79), Expect = 2.2 Identities = 58/220 (26%), Positives = 83/220 (37%), Gaps = 41/220 (18%) Query: 267 LGGRGGVQVPAVDISSSLGGRAVEVQGPSLESGDHGKIKFPTMKVPKFGVSTGREGQTPK 326 LG G +P D + G + GP GD G FP K S G G+ + Sbjct: 679 LGKCGDPGLPGPDGEPGIPG--IGFPGPPGPKGDQG---FPGTKG-----SLGCPGKMGE 728 Query: 327 AGLRVSAPEVSVGHKGGKPGLTIQAPQLEVSVPSANIEGLEGKLKGPQITGPSLE-GDLG 385 GL GKPGL + V++P G G P G S E G++G Sbjct: 729 PGLP------------GKPGLPGAKGEPAVAMP-----GGPGTPGFPGERGNSGEHGEIG 771 Query: 386 LKGAK----PQGHIGVDASAPQIGGSITGPSVEVQAPDIDVQGPGSKLNVPKMKVPKFSV 441 L G G+ G+D P+ GP E P ++GP +P + Sbjct: 772 LPGLPGLPGTPGNEGLDG--PRGDPGQPGPPGEQGPPGRCIEGPRGAQGLP-------GL 822 Query: 442 SGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLEG 481 +G KG++ T P G+ +PG+ E + G+ G Sbjct: 823 NGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPG 862 Score = 33.9 bits (76), Expect = 4.9 Identities = 71/288 (24%), Positives = 100/288 (34%), Gaps = 60/288 (20%) Query: 2535 PKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPKISMPDFDLHLKG---- 2590 PK ++ +SG K D +GP G P P P P + L+G Sbjct: 582 PKGELALSGEKGD--------QGPPGDPGSPGSPGPAGPAGPPGYG-PQGEPGLQGTQGV 632 Query: 2591 PKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKMPKVKMPKFSMPG 2650 P G + P+ E + P GP P G QGP PG Sbjct: 633 PGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHP--GPQGP----------------PG 674 Query: 2651 FKGE-GPDGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKLKGPKFKMPEMNIKAP-KIS 2708 G G GD LP D + P + GP GP+G P K ++ P K+ Sbjct: 675 IPGSLGKCGDPGLPGPDGEPGIPGIGFPGPP----GPKGDQGFPGTKG---SLGCPGKMG 727 Query: 2709 MPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPK 2768 P + P KG+ V++P G P + + HG + Sbjct: 728 EPGLPGKPGLPGAKGEPAVAMPGGPGT----------PGFPGERGNSGEHG--------E 769 Query: 2769 IKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGPEG 2816 I +P +PG G + ++ P+ D GP + P IEGP G Sbjct: 770 IGLP--GLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRG 815 >gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo sapiens] Length = 1670 Score = 56.6 bits (135), Expect = 7e-07 Identities = 141/553 (25%), Positives = 191/553 (34%), Gaps = 92/553 (16%) Query: 5156 EGDLKGPKVQANLGAPDI-NIEGLDAKVKTPSFGISAPQVSIPDVNVNLKG-PKIKGDVP 5213 +G+ P + LG P I GL + P+ D+ ++ KG P + G Sbjct: 129 KGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPA--------KEEDIELDAKGDPGLPGAPG 180 Query: 5214 SVGLEGPD-----VDLQGPEAKIKFPKFSMPK-------------IGIPGVK-MEGGGAE 5254 GL GP V GP FP P+ G GVK + G Sbjct: 181 PQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGP 240 Query: 5255 VHAQLPSLEGDLRGPDVKLEGPDVSLKG-PGVDLPS--VNLSMPKVSGPDLDLNLKGPSL 5311 + +L G D+K E D G PG PS S G D L+G Sbjct: 241 PGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPGLQGKPG 300 Query: 5312 KGDLDASVPSMKVHA----PGL-NLSGVGG-KMQVGGDGVKVPGIDATTKLNVGAPDVTL 5365 K + S V PGL G+ G K +G G + P T G + T Sbjct: 301 KDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKG-DEGTP 359 Query: 5366 RGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAK 5425 P +G G P V G+P S G+ P +K + PG D Sbjct: 360 GPPGPRGARGPQGPSGPPGVP-GSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPG 418 Query: 5426 GPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEI---KGPTVGGGLPG 5482 P +G PG+ P G G G+I KGP GLPG Sbjct: 419 SPGCAGS---PGL--------------------PGSPGPPGPPGDIVFRKGPPGDHGLPG 455 Query: 5483 I----GVQGLEGNLQMPGIKSSGCDV-----NLPGVNVKLPTGQISGPEIKGGLKGSE-- 5531 G+ G++G PG+ + C LPG+ I G + GLKGS Sbjct: 456 YLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGS 515 Query: 5532 ---------VGFHGAAPDISVKGPAFNMASPESDFGI----NLKG-PKIKGGADVSGGVS 5577 GF GA D +KG PE G+ L+G P KG + G Sbjct: 516 PGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPG 575 Query: 5578 APDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQA 5637 + +G L++ G G+ P + G GP+ E G++G Q A Sbjct: 576 VKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGA 635 Query: 5638 PG-LSVSGPQGHL 5649 PG +GP+G L Sbjct: 636 PGPPGEAGPRGEL 648 Score = 48.9 bits (115), Expect = 1e-04 Identities = 117/478 (24%), Positives = 164/478 (34%), Gaps = 96/478 (20%) Query: 5203 LKGPKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQLPSL 5262 L GP + +P +G GP GP+ FP + +G PG KM G LP Sbjct: 687 LPGPDGEPGIPGIGFPGPP----GPKGDQGFPG-TKGSLGCPG-KMGEPGLPGKPGLPGA 740 Query: 5263 EGDLRGPDVKLEGPDVSLKGPG----------VDLPSVNLSMPKVSGPDLDLNLKGPSLK 5312 +G+ P V + G + PG + LP +P + G + L GP + Sbjct: 741 KGE---PAVAMPGGPGTPGFPGERGNSGEHGEIGLPG----LPGLPGTPGNEGLDGP--R 791 Query: 5313 GDLDASVPSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQG 5372 GD P + PG + G G + PG++ L+G QG Sbjct: 792 GDPGQPGPPGEQGPPGRCIEGPRGAQGL-------PGLNG------------LKGQ--QG 830 Query: 5373 DLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGE 5432 +G PK G P L G +PG H GP G+ Sbjct: 831 RRGKTG----PKGDPGIPGLDRSGFPGET------------GSPGIPGHQGEMGPL--GQ 872 Query: 5433 LKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNL 5492 PG + + GP P D + G++G G P G G+ G++G Sbjct: 873 RGYPG-NPGILGP----PGEDGVIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQR 927 Query: 5493 QMPGIKSSGCDVNLPGVN-VKLPTGQISGPEIKG-----GLKGSE--VGFHGAAPDISVK 5544 PG K D PG + + G P +KG G KG+ G G + Sbjct: 928 GTPGAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLP 987 Query: 5545 GPAFNMASPESDFGI--NLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQV 5602 GPA P D G N P ++G G + P G L G G P + Sbjct: 988 GPA-GPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGR---PGL 1043 Query: 5603 SSALNLDTSKFAGGLHFS------GPKVEGGVKG-----GQIGLQAP--GLSVSGPQG 5647 L K G GP + G+ G G++G P L +GP+G Sbjct: 1044 PGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEG 1101 Score = 42.0 bits (97), Expect = 0.018 Identities = 127/484 (26%), Positives = 169/484 (34%), Gaps = 103/484 (21%) Query: 5206 PKIKGDVPSVGLEGPDVDLQGP-EAKIKFPKFSMPKIGIPGVKMEGG--GAEVHAQLPSL 5262 P +KG + G +G D P ++I + G PG+K G G + + +P + Sbjct: 921 PGVKGQRGTPGAKGEQGDKGNPGPSEISHV---IGDKGEPGLKGFAGNPGEKGNRGVPGM 977 Query: 5263 EG--DLRGPDVKLEGPDVSLKGPGVDLPSV-NLSMPKVSG-PDLDLNLKGPSLKGDLDAS 5318 G L+G L GP GP DL S N P + G P N+ P KG Sbjct: 978 PGLKGLKG----LPGP-AGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTL 1032 Query: 5319 VPSMKVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSG 5378 + PGL G+ G G+ PG T+ G P T P L GD+ G Sbjct: 1033 GFPGRAGRPGL--PGIHGLQGDKGE----PGYSEGTR--PGPPGPT-GDPGLPGDMGKKG 1083 Query: 5379 DIKCPKV--------------SVGAP----------DLSLEASEGSIKLPKMKLPQFGIS 5414 ++ P S G+P DL + +G + P ++ P Sbjct: 1084 EMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPG 1143 Query: 5415 TPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGP 5474 PGS + +G Q + GP + G + P N KG GA G Sbjct: 1144 FPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPG----- 1198 Query: 5475 TVGGGLPG-IGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKG-------- 5525 GLPG G G G GI+ LPG + TG P +G Sbjct: 1199 --FPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPP 1256 Query: 5526 GLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGE 5585 G GS V I +KG +M P GP KG +G + P Sbjct: 1257 GPPGSHV--------IGIKGDKGSMGHP---------GP--KGPPGTAGDMGPP------ 1291 Query: 5586 GHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKG--GQIGLQAPGLSVS 5643 G L G+ G GP+ F G F G K E G G G IG P + Sbjct: 1292 GRLGAPGTPG-LPGPRGDPG-------FQG---FPGVKGEKGNPGFLGSIGPPGP-IGPK 1339 Query: 5644 GPQG 5647 GP G Sbjct: 1340 GPPG 1343 Score = 41.6 bits (96), Expect = 0.024 Identities = 92/347 (26%), Positives = 129/347 (37%), Gaps = 50/347 (14%) Query: 5200 NVNLKG-PKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGG--GAEVH 5256 N L G P G GL+G + PE ++ P G PG++ + G G + Sbjct: 518 NTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVP-------GDPGLRGQPGRKGLDGI 570 Query: 5257 AQLPSLEGDLRGPDVKL--------EGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKG 5308 P ++G L GP +L +GP PG P+ P GP + L+G Sbjct: 571 PGTPGVKG-LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGY-GPQGEPGLQG 628 Query: 5309 PSLKGDLDASVPSMKVHAPGL-NLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPDVTLRG 5367 VP APG +G G++ V VPG G P Sbjct: 629 TQ-------GVPG----APGPPGEAGPRGELSVS---TPVPGPPGPP----GPPG----H 666 Query: 5368 PSLQGDLAVSGDI-KCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKG 5426 P QG + G + KC + PD E I P P+ PG+ + G Sbjct: 667 PGPQGPPGIPGSLGKCGDPGLPGPDG--EPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPG 724 Query: 5427 PQVSGELKG-PGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGI-G 5484 L G PG+ P ++ P P +G+ G GEI P + G LPG G Sbjct: 725 KMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPG-LPGTPG 783 Query: 5485 VQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSE 5531 +GL+G PG + PG ++ P G P + GLKG + Sbjct: 784 NEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGL-NGLKGQQ 829 Score = 36.2 bits (82), Expect = 0.99 Identities = 91/341 (26%), Positives = 116/341 (34%), Gaps = 48/341 (14%) Query: 5241 IGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLS------M 5294 +G+PG G++ P L G L P + KG + L + Sbjct: 120 VGVPGCS----GSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGL 175 Query: 5295 PKVSGPDLDLNLKGP-SLKGDLDASVPSMKVHAPG-LNLSGVGGKM------QVGGDGVK 5346 P GP L GP G + P PG + G G M G GVK Sbjct: 176 PGAPGPQ---GLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVK 232 Query: 5347 ----VPGIDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIK 5402 PG T + + PD +GD G+ P S G P S + +G+ Sbjct: 233 GLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPS-GLPGESYGSEKGAPG 291 Query: 5403 LPKMKLPQFGISTPGSDLHVNAKG----PQVSGE--LKGPGVDVNLKGPRISAPNVDFNL 5456 P ++ PG KG P + GE +KG D+ G R D Sbjct: 292 DPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQ 351 Query: 5457 EG--------PKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPGIKSSGCDVNLPG 5508 E P +G+ G G GP G PG GL G PG+K S + PG Sbjct: 352 EKGDEGTPGPPGPRGARGPQGP-SGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPG 410 Query: 5509 VNVKLPTGQISGPEIKG--GLKGSEVGFHGAAPDISV-KGP 5546 K G P G GL GS G G DI KGP Sbjct: 411 ---KDAMGTPGSPGCAGSPGLPGSP-GPPGPPGDIVFRKGP 447 Score = 35.8 bits (81), Expect = 1.3 Identities = 123/475 (25%), Positives = 164/475 (34%), Gaps = 73/475 (15%) Query: 5156 EGDLKG-PKVQANLGAPDINIEGLDAKVKTPSFGISAPQVSIPDVNVNLKGPKIKGDVPS 5214 E L+G P N+G P G K T F A + +P ++ L+G K + Sbjct: 1007 EPGLRGIPGSMGNMGMP-----GSKGKRGTLGFPGRAGRPGLPGIH-GLQGDKGEPGYSE 1060 Query: 5215 VGLEGP-----DVDLQGPEAKIKFPKFSMPKIGIPGVKMEGG--GAEVHAQLPSLEGDLR 5267 GP D L G K K M + G PG G GA P L G Sbjct: 1061 GTRPGPPGPTGDPGLPGDMGK----KGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGK-P 1115 Query: 5268 GP--DVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMKVH 5325 GP D+ +G L PG+ P P GP + ++G + + P+ + Sbjct: 1116 GPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP---MGIRGDQGRDGIPG--PAGEKG 1170 Query: 5326 APGLNLSGVGGKMQVGGDGVK----VPGIDATTKLNVGAPDVTLRGPS----LQGDLAVS 5377 GL + G + G G K PG D RGP+ G + Sbjct: 1171 ETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLP 1230 Query: 5378 GDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQ----FGIS-TPGSDLHVNAKGPQVSGE 5432 G I + P S GS P P GI GS H KGP + Sbjct: 1231 GAIIPGQTGNRGPP----GSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG 1286 Query: 5433 LKGPGVDVNLKG-PRISAPNVDFNLEG-PKVKGSLGATGEI-----KGPTVGGGLPGIGV 5485 GP + G P + P D +G P VKG G G + GP G PG V Sbjct: 1287 DMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPG--V 1344 Query: 5486 QGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAPDISVKG 5545 +G G L++ + S PG P G P ++G E G G ++ G Sbjct: 1345 RGDPGTLKIISLPGS------PG-----PPGTPGEPGMQG-----EPGPPGPPGNL---G 1385 Query: 5546 PAFNMASPESDFGINLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGP 5600 P P D GP + G S G P S +G +KG G+ P Sbjct: 1386 PCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGS--DGLPGLKGKRGDSGSP 1438 Score = 35.0 bits (79), Expect = 2.2 Identities = 58/220 (26%), Positives = 83/220 (37%), Gaps = 41/220 (18%) Query: 267 LGGRGGVQVPAVDISSSLGGRAVEVQGPSLESGDHGKIKFPTMKVPKFGVSTGREGQTPK 326 LG G +P D + G + GP GD G FP K S G G+ + Sbjct: 679 LGKCGDPGLPGPDGEPGIPG--IGFPGPPGPKGDQG---FPGTKG-----SLGCPGKMGE 728 Query: 327 AGLRVSAPEVSVGHKGGKPGLTIQAPQLEVSVPSANIEGLEGKLKGPQITGPSLE-GDLG 385 GL GKPGL + V++P G G P G S E G++G Sbjct: 729 PGLP------------GKPGLPGAKGEPAVAMP-----GGPGTPGFPGERGNSGEHGEIG 771 Query: 386 LKGAK----PQGHIGVDASAPQIGGSITGPSVEVQAPDIDVQGPGSKLNVPKMKVPKFSV 441 L G G+ G+D P+ GP E P ++GP +P + Sbjct: 772 LPGLPGLPGTPGNEGLDG--PRGDPGQPGPPGEQGPPGRCIEGPRGAQGLP-------GL 822 Query: 442 SGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLEG 481 +G KG++ T P G+ +PG+ E + G+ G Sbjct: 823 NGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPG 862 Score = 33.9 bits (76), Expect = 4.9 Identities = 71/288 (24%), Positives = 100/288 (34%), Gaps = 60/288 (20%) Query: 2535 PKADVDISGPKVDIEGPDVNIEGPEGKLKGPKLKMPEMNIKAPKISMPDFDLHLKG---- 2590 PK ++ +SG K D +GP G P P P P + L+G Sbjct: 582 PKGELALSGEKGD--------QGPPGDPGSPGSPGPAGPAGPPGYG-PQGEPGLQGTQGV 632 Query: 2591 PKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDINAPDVGVQGPDWHLKMPKVKMPKFSMPG 2650 P G + P+ E + P GP P G QGP PG Sbjct: 633 PGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHP--GPQGP----------------PG 674 Query: 2651 FKGE-GPDGDVKLPKADIDVSGPKVDIEGPDVNIEGPEGKLKGPKFKMPEMNIKAP-KIS 2708 G G GD LP D + P + GP GP+G P K ++ P K+ Sbjct: 675 IPGSLGKCGDPGLPGPDGEPGIPGIGFPGPP----GPKGDQGFPGTKG---SLGCPGKMG 727 Query: 2709 MPDIDLNLKGPKVKGDVDVSLPKVEGDLKGPEVDIKGPKVDIDAPDVDVHGPDWHLKMPK 2768 P + P KG+ V++P G P + + HG + Sbjct: 728 EPGLPGKPGLPGAKGEPAVAMPGGPGT----------PGFPGERGNSGEHG--------E 769 Query: 2769 IKMPKISMPGFKGEGPDVDVNLPKADIDVSGPKVDVECPDVNIEGPEG 2816 I +P +PG G + ++ P+ D GP + P IEGP G Sbjct: 770 IGLP--GLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRG 815 >gi|126352322 elastin isoform c precursor [Homo sapiens] Length = 692 Score = 56.2 bits (134), Expect = 9e-07 Identities = 124/472 (26%), Positives = 164/472 (34%), Gaps = 64/472 (13%) Query: 5210 GDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEG---GGAEVHAQLPS---LE 5263 G VP VG G P A + P + +PGV + G GG A+ P L Sbjct: 113 GGVPGVGGLGVSAAPSVPGAVVPQPGAGVKPGKVPGVGLPGVYPGGVLPGARFPGVGVLP 172 Query: 5264 GDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSMK 5323 G G VK + P V G +P V G L +K P L G + K Sbjct: 173 GVPTGAGVKPKAPGVG--GAFAGIPGVGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGK 230 Query: 5324 V---HAPGLNLSGVGGKMQ------VGGDGVKVPGIDATTKLNVGA----PDVTLRG-PS 5369 + + PG ++G GK VG A K GA P V G P Sbjct: 231 LPYGYGPG-GVAGAAGKAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPG 289 Query: 5370 LQGDLAVSGDIK---CPKVSVGAPDLSLEASEGSIKLPKMKLPQFG---ISTPGSDLHVN 5423 + G + G I P + A + A G+ P FG + PG+ V Sbjct: 290 VPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAG--VP 347 Query: 5424 AKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGG----- 5478 G +G PG + P + P V K G G VGG Sbjct: 348 GVGVPGAGIPVVPGAGI----PGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYG 403 Query: 5479 ----GLPG--IGVQGLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEV 5532 G PG +GV G+ G +PG+ +PGV + P Q + K G Sbjct: 404 VGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGIS-PEAQ-AAAAAKAAKYGLVP 461 Query: 5533 GFHGAAPDISVKGPAFNMASPESDFGINL-KGPKIKGGADVSGGVS-APDISLGEGHLSV 5590 G G AP + V P +A G+ L G + G V+ GV AP I G + Sbjct: 462 GV-GVAPGVGV-APGVGVAP-----GVGLAPGVGVAPGVGVAPGVGVAPGIGPGGVAAAA 514 Query: 5591 KGSGGEWKGPQVSSALNLDTSKFAGGLHFSGPKVEGGVKGGQIGLQAPGLSV 5642 K + Q+ +A L G G V GV G +G PGL V Sbjct: 515 KSAAKVAAKAQLRAAAGL-------GAGIPGLGVGVGVPGLGVGAGVPGLGV 559 Score = 38.1 bits (87), Expect = 0.26 Identities = 88/316 (27%), Positives = 126/316 (39%), Gaps = 55/316 (17%) Query: 5185 PSFG---ISAPQVSIPDVNVNLKGPKIKGDVPSVGLEGPDVD-LQGPEAKIKFP----KF 5236 P FG + P +P V V G + VP G+ G V + PEA K K+ Sbjct: 332 PGFGPGVVGVPGAGVPGVGVPGAGIPV---VPGAGIPGAAVPGVVSPEAAAKAAAKAAKY 388 Query: 5237 -SMPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVD-LPSVNLSM 5294 + P +G+ G+ G GA G G V + G PGV +P V + Sbjct: 389 GARPGVGVGGIPTYGVGA----------GGFPGFGVGVGGIPGVAGVPGVGGVPGVG-GV 437 Query: 5295 PKVS-GPDLDLNLKGPSLKGDLDASVPSMKVHAPGLNLS-GVGGKMQVG---GDGVKVPG 5349 P V P+ + K L VP + V APG+ ++ GVG VG G GV PG Sbjct: 438 PGVGISPEAQAAAAAKAAKYGL---VPGVGV-APGVGVAPGVGVAPGVGLAPGVGV-APG 492 Query: 5350 IDATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEG-SIKLPKMKL 5408 + + V AP + GP G +A + KV+ A L A+ G +P + + Sbjct: 493 VGVAPGVGV-APGI---GP---GGVAAAAK-SAAKVAAKA---QLRAAAGLGAGIPGLGV 541 Query: 5409 PQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGAT 5468 G+ PG + G V + G G + G +A + G V G LG Sbjct: 542 ---GVGVPGLGVGAGVPGLGVGAGVPGFGA---VPGALAAAKAAKY---GAAVPGVLGGL 592 Query: 5469 GEIKGPTVGGGLPGIG 5484 G + G + GG+ G G Sbjct: 593 GALGGVGIPGGVVGAG 608 Score = 38.1 bits (87), Expect = 0.26 Identities = 84/358 (23%), Positives = 125/358 (34%), Gaps = 68/358 (18%) Query: 5238 MPKIGIPGVKMEGGGAEVHAQLPSLEGDLRGPDVKLEGPDVSLKGPGVDLPSVNLSMPKV 5297 +P G+PGV + G G V P + G V PGV P Sbjct: 341 VPGAGVPGVGVPGAGIPVV------------PGAGIPGAAV----PGVVSPEAAAKAAAK 384 Query: 5298 S---GPDLDLNLKGPSLKGDLDASVPSMKVHAPGL----NLSGVGGKMQVGGDGVKVPGI 5350 + G + + G G P V G+ + GVGG VGG VPG+ Sbjct: 385 AAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGG----VPGV 440 Query: 5351 DATTKLNVGAPDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQ 5410 + + A + + G G P V V AP + L G P Sbjct: 441 GISPEAQAAAAAKAAKYGLVPGVGVAPGVGVAPGVGV-APGVGLAPGVGVA-------PG 492 Query: 5411 FGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNLEGPKVKGSLGATGE 5470 G++ PG + P + GPG G +A + +++ + G Sbjct: 493 VGVA-PGVGV-----APGI-----GPG------GVAAAAKSAAKVAAKAQLRAAAGLGAG 535 Query: 5471 IKGPTVGGGLPGIGV----------QGLEGNLQMPG----IKSSGCDVNLPGVNVKLPTG 5516 I G VG G+PG+GV G+ G +PG K++ +PGV L G Sbjct: 536 IPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGAVPGALAAAKAAKYGAAVPGVLGGL--G 593 Query: 5517 QISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKGPKIKGGADVSG 5574 + G I GG+ G+ AA + K F + G+ + G + G + G Sbjct: 594 ALGGVGIPGGVVGAGPAAAAAAAKAAAKAAQFGLVGAAGLGGLGVGGLGVPGVGGLGG 651 >gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens] Length = 1142 Score = 56.2 bits (134), Expect = 9e-07 Identities = 145/543 (26%), Positives = 189/543 (34%), Gaps = 85/543 (15%) Query: 5206 PKIKGDVPSVGLEGPDVDLQGPEAKIKFP-KFSMP-KIGIPGVKMEGGGAEVHAQLPSLE 5263 P +KG S G GP +GP + P + +P K GI G K + GG LP + Sbjct: 521 PGLKGQQGSAGSMGP----RGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPK 576 Query: 5264 GDLRGPDVKLEGP---DVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVP 5320 G+ P L G D + PG P +P V G D+ +G + G A P Sbjct: 577 GEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGLPGVHGSPGDIGPQGIGIPGRTGAQGP 636 Query: 5321 SMKVHAPG-LNLSGVGGKMQV-GGDGVKVPGIDATTKLNVGAPDVTLRGPSLQGDLAVSG 5378 + + G L G+ G G DGV PG D L G P + P L GD+ Sbjct: 637 AGEPGIQGPRGLPGLPGTPGTPGNDGV--PGRDGKPGLP-GPPGDPIALPLL-GDIGALL 692 Query: 5379 DIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGV 5438 C P L E + G PG + KG Sbjct: 693 KNFCGNCQASVPGLKSNKGE-----------EGGAGEPGKYDSMARKG------------ 729 Query: 5439 DVNLKGPRISAPNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGIGVQGLEGNLQMPGIK 5498 D+ +GP P + EGPK G+ GE P + G G+QG+ G PG Sbjct: 730 DIGPRGP----PGIP-GREGPK-----GSKGERGYPGIPGEKGDEGLQGIPGIPGAPG-- 777 Query: 5499 SSGCDVNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFG 5558 PG+ + TG GP G KGS+ G G G FN + S Sbjct: 778 ----PTGPPGLMGR--TGH-PGPTGAKGEKGSD-GPPGKPGPPGPPGIPFNERNGMSSL- 828 Query: 5559 INLKGPKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGPQVSSALNLDTSKFAGGLH 5618 KIKGG +V P G KG G P L+ F G Sbjct: 829 -----YKIKGGVNVPSYPGPP------GPPGPKGDPGPVGEPGAMGLPGLE--GFPGVKG 875 Query: 5619 FSGPKVEGGVKGGQIGLQAPG-LSVSGPQGHLESGSGKVTFPKMKIP--KFTFSGRELVG 5675 GP G+ G APG V G G G + FP + P K +G++ + Sbjct: 876 DRGPAGPPGIAGMSGKPGAPGPPGVPGEPGE-RGPVGDIGFPGPEGPSGKPGINGKDGIP 934 Query: 5676 REMGV----DVHFPKAEASIQAGAGD--GEWEESEVKLKKSKIKMPKFNFSKPKGKGGVT 5729 G+ PK E Q GD + E + L K + P G G Sbjct: 935 GAQGIMGKPGDRGPKGERGDQGIPGDRGSQGERGKPGLTGMKGAIGPMG---PPGNKGSM 991 Query: 5730 GSP 5732 GSP Sbjct: 992 GSP 994 >gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] Length = 1745 Score = 55.8 bits (133), Expect = 1e-06 Identities = 137/510 (26%), Positives = 180/510 (35%), Gaps = 125/510 (24%) Query: 5204 KGPKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPK--IGIPGVKMEGG-----GAEVH 5256 KG + +G + G +G V GP FP P G+PG+ G G + Sbjct: 386 KGQQFEGPPGAPGPQGV-VGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIM 444 Query: 5257 AQLPSLEGDLRGPDVK---------LEGPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLK 5307 G +GP V L+ +S+KGP + ++G + L Sbjct: 445 MPFQFAGGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVG--------LTGRPGPVGLP 496 Query: 5308 G-PSLKGDLDASVPS-----MKVHAPGLNLSGVGGKM-QVGGDGVK-VPGIDATTKLNVG 5359 G P LKG+ A P H P G GKM + G DG + +PG D K + G Sbjct: 497 GHPGLKGEEGAEGPQGPRGLQGPHGP----PGRVGKMGRPGADGARGLPG-DTGPKGDRG 551 Query: 5360 APDVTLRGPSLQGDLAVSGDIKCPKVSVGAPDLSLEASEGSIKLPKMKLPQFGISTPGSD 5419 + P L G+ GD VG P PG D Sbjct: 552 FDGL----PGLPGEKGQRGDFG----HVGQP-----------------------GPPGED 580 Query: 5420 LHVNAKGPQ-VSGELKGPGVDVNLKGPRISA-----PNVDFNLEGPKVKGSLGATGEIKG 5473 A+GP +G+ PG L GPR S P V P KG++G GE Sbjct: 581 GERGAEGPPGPTGQAGEPGPR-GLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGP 639 Query: 5474 PTVGG-----GLPG-------IGVQGLEGNLQMPGIKSSGCDVNLPG-------VNVKLP 5514 P G GLPG G +G GN +PG+ S + PG + P Sbjct: 640 PGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGP 699 Query: 5515 TGQISGPEIKG--GLKGS--------------EVGFHGAAPDISVKGPAFNMASPESDFG 5558 G P G G+KG+ E GF G D+ +KG +P Sbjct: 700 PGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGE 759 Query: 5559 INLKGPKIKGGADVSGGVSAPDISLGE-GHLSVKGSGGEWKGPQVSSALNLDTSKFAGGL 5617 +GPK + G G P S GE G L V G G P ++ F G L Sbjct: 760 DGPEGPKGQAG---QAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIG-----FPGPL 811 Query: 5618 HFSGPKVEGGVKGGQIGLQAPGLSVSGPQG 5647 G K + G K GQ GL+ GP G Sbjct: 812 GPIGEKGKSG-KTGQPGLEGE----RGPPG 836 Score = 42.0 bits (97), Expect = 0.018 Identities = 101/369 (27%), Positives = 123/369 (33%), Gaps = 53/369 (14%) Query: 211 GSGAASPTGSAVDIRA-GAISASG-PELQGAGHSKLQVTMPGIKVGGSGVNVNAKGLDLG 268 G G PTG D G + A+G P +G + +PG V K G Sbjct: 984 GPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRG 1043 Query: 269 GRGGVQVPAVD-ISSSLGGRAVE-VQGPSLESGDHGKIKFPTMKVPKFGVSTGREGQTPK 326 RG D I LG GPS E GD G + P K K G G + Sbjct: 1044 ERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKG--DKGDAGPPGQ 1101 Query: 327 AGLRVSA----PEVSVGHKG--GKPGLTIQAPQLEVSVPSANIEGLEGKLKGPQITGPSL 380 G+R A P + G +G G PGL Q + G G + GP P L Sbjct: 1102 PGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGD-------DGVRGFVGVI-GP----PGL 1149 Query: 381 EGDLGLKGAKPQGHIG-VDASAPQIGGSITGPSVEVQAPDIDVQGPGSKLNVPKMK--VP 437 +G G G K G +G V + P GP QGP P + V Sbjct: 1150 QGLPGPPGEK--GEVGDVGSMGPHGAPGPRGP-----------QGPTGSEGTPGLPGGVG 1196 Query: 438 KFSVSGAKGEETGIDVTLPTGEVTVPGVSGDVSLPEIATGGLEGKMKGTKVKTPEMIIQK 497 + G KGE P G +PG GD+ E G G K P Sbjct: 1197 QPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIG--EKGDSGPSGAAGPPGKKGPP----- 1249 Query: 498 PKISMQDVDLSLGSPKLKGDI-KVSAPGVQGDVKGPQVALKGSRVDIETPNLEGTLTGPR 556 S+G L GD+ PGV G P KG D+ P G P Sbjct: 1250 ---GEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSP--GEKGDPGDVGGPGPPGASGEPG 1304 Query: 557 LGSPSGKTG 565 P GK G Sbjct: 1305 APGPPGKRG 1313 Score = 41.6 bits (96), Expect = 0.024 Identities = 78/272 (28%), Positives = 97/272 (35%), Gaps = 44/272 (16%) Query: 5397 SEGSIKLPKMKLPQFGISTPGSDLHVNAKGPQVSGELKGPGVDVNLKGPRISAPNVDFNL 5456 SEG+ LP G+ PG+ V KG + G+ PG P I P D Sbjct: 1185 SEGTPGLPG------GVGQPGA---VGEKGER--GDAGDPGPP---GAPGIPGPKGDIGE 1230 Query: 5457 EGPK-VKGSLGATGEIKGPTVGGGLPGIGVQGLEGNL------------QMPGIKSSGCD 5503 +G G+ G G+ P G +G GL G+L PG K D Sbjct: 1231 KGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGD 1290 Query: 5504 VNLPGVNVKLPTGQISGPEIKGGLKGSEVGFHGAAPDISVKGPAFNMASPESDFGINLKG 5563 V PG GP K G G +G G + KG P + +G Sbjct: 1291 VGGPGPPGASGEPGAPGPPGKRGPSG-HMGREGREGEKGAKGEPGPDGPPGRTGPMGARG 1349 Query: 5564 PKIKGGADVSGGVSAPDISLGE-GHLSVKGSGGE--WKGPQVSSALNLDTSK-----FAG 5615 P + G + G+ P +GE G L G G GP L DT G Sbjct: 1350 PPGRVGPEGLRGIPGP---VGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIG 1406 Query: 5616 GLHFSGPKVEGGVKGGQIGLQAPGLSVSGPQG 5647 + GP E G KG Q GL PG V GP G Sbjct: 1407 LIGLIGPPGEAGEKGDQ-GL--PG--VQGPPG 1433 Score = 40.4 bits (93), Expect = 0.053 Identities = 125/457 (27%), Positives = 158/457 (34%), Gaps = 82/457 (17%) Query: 5206 PKIKGDVPSVGLEGPDVDLQGPEAKIKFPKFSMPKIGIPGVKMEGGGAEVHAQL-PSLEG 5264 P I G+ GL+GP GP K P K G PG + G Q P Sbjct: 862 PGIPGEKGLPGLQGPP-GFPGP----KGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPA 916 Query: 5265 DLRGPDVKLE--GPDVSLKGPGVDLPSVNLSMPKVSGPDLDLNLKGPSLKGDLDASVPSM 5322 + GP K GP PG P +P + G + KG+L P Sbjct: 917 GVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGRE--------GAKGELGPPGPLG 968 Query: 5323 KVHAPGLNLSGVGGKMQVGGDGVKVPGIDATTKLNVGAPD-VTLRG-PSLQGDLAVSGDI 5380 K GL G GG G P K + G P V G P +G L +G I Sbjct: 969 KEGPAGLR----GFPGPKGGPGDPGP---TGLKGDKGPPGPVGANGSPGERGPLGPAGGI 1021 Query: 5381 KCPKVSVGAPDLSLEASEGSI--KLPKMKLPQFGISTPGSDLHV-NAKGPQVSGELKGPG 5437 P S + +GS + P + GI P L A GP SGE +G Sbjct: 1022 GLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGP--SGE-EGDK 1078 Query: 5438 VDVNLKGPRISA-----------PNVDFNLEGPKVKGSLGATGEIKGPTVGGGLPGIGVQ 5486 DV G + S P + P G+ GA G P + G GV+ Sbjct: 1079 GDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVR 1138 Query: 5487 GLEGNLQMPGIKSSGCDVNLPGVNVKLPTGQISGPEIKG--GLKGSEVGFHGAAPDISVK 5544 G G + PG++ LPG P G+ KG G GS +G HGA + Sbjct: 1139 GFVGVIGPPGLQ------GLPG-----PPGE------KGEVGDVGS-MGPHGAPGPRGPQ 1180 Query: 5545 GPAFNMASPESDFGINLKG----PKIKGGADVSGGVSAPDISLGEGHLSVKGSGGEWKGP 5600 GP + +P G+ G +G A G AP I +G + KG G Sbjct: 1181 GPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSG----- 1235 Query: 5601 QVSSALNLDTSKFAGGLHFSGPKVEGGVKG--GQIGL 5635 S AG GP E G KG G GL Sbjct: 1236 ---------PSGAAGPPGKKGPPGEDGAKGSVGPTGL 1263 Score = 37.4 bits (85), Expect = 0.44 Identities = 69/255 (27%), Positives = 96/255 (37%), Gaps = 44/255 (17%) Query: 293 GPSLESGDHGKIKFPTMKVPKFGVST-GREGQTPKAGLR----VSAPEVSVGHKGGKPGL 347 GP + G+HG P P+ + T G +G G+ P GH+G Sbjct: 638 GPPGQQGNHGSQGLPG---PQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEK 694 Query: 348 TIQAPQLEVSVP----------SANIEGLEGKLKGPQITG-PSLEGDLGLKGAKPQGHIG 396 Q P P ++ GL+G+ G P +GD+GLKG QG G Sbjct: 695 GAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKG--DQGKPG 752 Query: 397 VDASAPQIGGSITGPSVEVQAPDIDVQG-PGSKLNVPKMKVPKF-SVSGAKGEETGIDVT 454 A P+ GP + QA +G PGS K+ VP G G + I Sbjct: 753 --APGPRGEDGPEGP--KGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFP 808 Query: 455 LPTGEVTVPGVSGDVSLPEIATGGLEGKMKGTKVKTPEMIIQKPKISMQDVDLSLGSPKL 514 P G + G SG P GLEG+ +G E + + G P Sbjct: 809 GPLGPIGEKGKSGKTGQP-----GLEGE-RGPPGSRGE----------RGQPGATGQPGP 852 Query: 515 KGDI-KVSAPGVQGD 528 KGD+ + APG+ G+ Sbjct: 853 KGDVGQDGAPGIPGE 867 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.138 0.408 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 272,669,078 Number of Sequences: 37866 Number of extensions: 15498268 Number of successful extensions: 95646 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 12 Number of HSP's successfully gapped in prelim test: 208 Number of HSP's that attempted gapping in prelim test: 25854 Number of HSP's gapped (non-prelim): 3350 length of query: 5890 length of database: 18,247,518 effective HSP length: 125 effective length of query: 5765 effective length of database: 13,514,268 effective search space: 77909755020 effective search space used: 77909755020 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 74 (33.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.