Search of human proteins with 5729991

Search of human proteins with 5729991

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo
sapiens]
         (418 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens]   818   0.0  
gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit ...   800   0.0  
gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo sapi...   742   0.0  
gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]            393   e-109
gi|169167838 PREDICTED: similar to hCG2002932 [Homo sapiens]          317   1e-86
gi|239748566 PREDICTED: similar to hCG2002932 [Homo sapiens]          317   1e-86
gi|239742549 PREDICTED: hypothetical protein LOC345645 [Homo sap...   317   1e-86
gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens]            316   2e-86
gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens]            316   3e-86
gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens]           306   3e-83
gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens]             285   5e-77
gi|157671927 spermatogenesis associated 5 [Homo sapiens]              223   3e-58
gi|6005942 valosin-containing protein [Homo sapiens]                  195   6e-50
gi|5802970 AFG3 ATPase family gene 3-like 2 [Homo sapiens]            186   3e-47
gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]                 185   6e-47
gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]                 185   6e-47
gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens]       174   1e-43
gi|4507173 spastic paraplegia 7 isoform 1 [Homo sapiens]              170   3e-42
gi|4505725 peroxin1 [Homo sapiens]                                    157   1e-38
gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]           157   2e-38
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]     155   6e-38
gi|21327685 YME1-like 1 isoform 1 [Homo sapiens]                      152   7e-37
gi|7657689 YME1-like 1 isoform 3 [Homo sapiens]                       152   7e-37
gi|31742536 fidgetin-like 1 [Homo sapiens]                            151   1e-36
gi|112789543 fidgetin-like 1 [Homo sapiens]                           151   1e-36
gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens]   150   3e-36
gi|5901990 katanin p60 subunit A 1 [Homo sapiens]                     144   1e-34
gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens]               143   3e-34
gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens]               143   3e-34
gi|17865802 vacuolar protein sorting factor 4B [Homo sapiens]         138   1e-32

>gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens]
          Length = 418

 Score =  818 bits (2113), Expect = 0.0
 Identities = 418/418 (100%), Positives = 418/418 (100%)

Query: 1   MEEIGILVEKAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEY 60
           MEEIGILVEKAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEY
Sbjct: 1   MEEIGILVEKAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEY 60

Query: 61  IKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTID 120
           IKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTID
Sbjct: 61  IKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTID 120

Query: 121 RELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREA 180
           RELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREA
Sbjct: 121 RELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREA 180

Query: 181 VELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYL 240
           VELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYL
Sbjct: 181 VELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYL 240

Query: 241 GEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFD 300
           GEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFD
Sbjct: 241 GEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFD 300

Query: 301 QNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDL 360
           QNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDL
Sbjct: 301 QNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDL 360

Query: 361 EDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK 418
           EDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK
Sbjct: 361 EDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK 418


>gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit 4
           [Homo sapiens]
          Length = 414

 Score =  800 bits (2067), Expect = 0.0
 Identities = 408/409 (99%), Positives = 409/409 (100%)

Query: 10  KAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLK 69
           +AQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLK
Sbjct: 6   EAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLK 65

Query: 70  KEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNAS 129
           KEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNAS
Sbjct: 66  KEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNAS 125

Query: 130 VALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFE 189
           VALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFE
Sbjct: 126 VALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFE 185

Query: 190 LYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRD 249
           LYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRD
Sbjct: 186 LYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRD 245

Query: 250 VFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIM 309
           VFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIM
Sbjct: 246 VFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIM 305

Query: 310 ATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDK 369
           ATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDK
Sbjct: 306 ATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDK 365

Query: 370 ISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK 418
           ISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK
Sbjct: 366 ISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK 414


>gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo
           sapiens]
          Length = 387

 Score =  742 bits (1915), Expect = 0.0
 Identities = 387/418 (92%), Positives = 387/418 (92%), Gaps = 31/418 (7%)

Query: 1   MEEIGILVEKAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYKKLQQELEFLEVQEEY 60
           MEEIGILVEKAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYK               
Sbjct: 1   MEEIGILVEKAQDEIPALSVSRPQTGLSFLGPEPEDLEDLYSRYK--------------- 45

Query: 61  IKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTID 120
                           EEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTID
Sbjct: 46  ----------------EEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTID 89

Query: 121 RELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREA 180
           RELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREA
Sbjct: 90  RELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREA 149

Query: 181 VELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYL 240
           VELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYL
Sbjct: 150 VELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYL 209

Query: 241 GEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFD 300
           GEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFD
Sbjct: 210 GEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFD 269

Query: 301 QNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDL 360
           QNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDL
Sbjct: 270 QNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDL 329

Query: 361 EDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK 418
           EDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK
Sbjct: 330 EDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK 387


>gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]
          Length = 440

 Score =  393 bits (1009), Expect = e-109
 Identities = 187/369 (50%), Positives = 282/369 (76%), Gaps = 2/369 (0%)

Query: 46  KLQQELEFLEVQEEYIKDEQ--KNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIV 103
           KL++  ++L ++EE+I++++  K L+++    + +V  ++  P+ +G   E +D N AIV
Sbjct: 64  KLERIKDYLLMEEEFIRNQEQMKPLEEKQEEERSKVDDLRGTPMSVGTLEEIIDDNHAIV 123

Query: 104 GSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVM 163
            ++ GS +YV ILS +D++LL+P  SV L+   +A++ VL  + D  + ++  ++ P   
Sbjct: 124 STSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQET 183

Query: 164 YADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHT 223
           YADIGG+D Q QE++E+VELPLTH E Y+++GI PP+GV++YGPPG GKT+LAKAVA+ T
Sbjct: 184 YADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQT 243

Query: 224 TAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADR 283
           +A F+RVVGSE +QKYLG+GP++VR++FR+A+E+AP+I+FIDEIDAI TKR+D+ +G +R
Sbjct: 244 SATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGER 303

Query: 284 EVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRL 343
           E+QR +LELLNQ+DGFD   +VKVIMATNR +TLDPAL+RPGR+DRKIEFPLPD + K+ 
Sbjct: 304 EIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKR 363

Query: 344 IFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAY 403
           IF   TS+M L+++V L+D +   D +SGADI +IC E+G++A+RE R  V  +DF+K+ 
Sbjct: 364 IFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSK 423

Query: 404 KTVIKKDEQ 412
           + V+ K ++
Sbjct: 424 ENVLYKKQE 432


>gi|169167838 PREDICTED: similar to hCG2002932 [Homo sapiens]
          Length = 415

 Score =  317 bits (812), Expect = 1e-86
 Identities = 157/371 (42%), Positives = 253/371 (68%), Gaps = 18/371 (4%)

Query: 46  KLQQELEFLEVQEEYIKDEQ--KNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIV 103
           KL++  ++L + EE+I++++  K L+++    + +V  ++  P+ +G   E +D N AIV
Sbjct: 51  KLERIKDYLLMVEEFIRNQEQIKLLEEKQEEGRSKVDDLRGTPMSVGNLEEIIDDNHAIV 110

Query: 104 GSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVM 163
            ++ GS +Y  I+S ++++LL+P  S+ L    +A++ VL  +    + M+  ++ P   
Sbjct: 111 STSVGSEHYDSIISFVEKDLLEPGCSILLRHKVHAVIGVLMDDTGPLVTMMKVEKAPQET 170

Query: 164 YADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHT 223
           Y + GG+D Q QE++E++ELPL H E Y+++G  PP+GV++ GPPG              
Sbjct: 171 YVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPG-------------- 216

Query: 224 TAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADR 283
           TA F+RVVGSE +QKYLG+GP++VR VF++A+E+AP+I+F DEI+AI TKR+D+ +G +R
Sbjct: 217 TATFLRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGER 276

Query: 284 EVQRILLEL--LNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQK 341
           E+Q+ +LEL  LNQ+ GFD   +VKVIMAT + +TLDP L+RPGR+D+KIEF LPD + K
Sbjct: 277 EIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKTK 336

Query: 342 RLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEK 401
           + IF   TS+M L+ +V L+D +   D  SGADI +IC E+G++A+RE+R     +DF+K
Sbjct: 337 KHIFQIHTSRMTLANDVTLDDLIMAKDDFSGADIKAICTEAGLMALREHRMKATNEDFKK 396

Query: 402 AYKTVIKKDEQ 412
           + ++V+ K  +
Sbjct: 397 SIESVLYKKHE 407


>gi|239748566 PREDICTED: similar to hCG2002932 [Homo sapiens]
          Length = 415

 Score =  317 bits (812), Expect = 1e-86
 Identities = 157/371 (42%), Positives = 253/371 (68%), Gaps = 18/371 (4%)

Query: 46  KLQQELEFLEVQEEYIKDEQ--KNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIV 103
           KL++  ++L + EE+I++++  K L+++    + +V  ++  P+ +G   E +D N AIV
Sbjct: 51  KLERIKDYLLMVEEFIRNQEQIKLLEEKQEEGRSKVDDLRGTPMSVGNLEEIIDDNHAIV 110

Query: 104 GSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVM 163
            ++ GS +Y  I+S ++++LL+P  S+ L    +A++ VL  +    + M+  ++ P   
Sbjct: 111 STSVGSEHYDSIISFVEKDLLEPGCSILLRHKVHAVIGVLMDDTGPLVTMMKVEKAPQET 170

Query: 164 YADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHT 223
           Y + GG+D Q QE++E++ELPL H E Y+++G  PP+GV++ GPPG              
Sbjct: 171 YVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPG-------------- 216

Query: 224 TAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADR 283
           TA F+RVVGSE +QKYLG+GP++VR VF++A+E+AP+I+F DEI+AI TKR+D+ +G +R
Sbjct: 217 TATFLRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGER 276

Query: 284 EVQRILLEL--LNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQK 341
           E+Q+ +LEL  LNQ+ GFD   +VKVIMAT + +TLDP L+RPGR+D+KIEF LPD + K
Sbjct: 277 EIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKTK 336

Query: 342 RLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEK 401
           + IF   TS+M L+ +V L+D +   D  SGADI +IC E+G++A+RE+R     +DF+K
Sbjct: 337 KHIFQIHTSRMTLANDVTLDDLIMAKDDFSGADIKAICTEAGLMALREHRMKATNEDFKK 396

Query: 402 AYKTVIKKDEQ 412
           + ++V+ K  +
Sbjct: 397 SIESVLYKKHE 407


>gi|239742549 PREDICTED: hypothetical protein LOC345645 [Homo
           sapiens]
          Length = 415

 Score =  317 bits (812), Expect = 1e-86
 Identities = 157/371 (42%), Positives = 253/371 (68%), Gaps = 18/371 (4%)

Query: 46  KLQQELEFLEVQEEYIKDEQ--KNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIV 103
           KL++  ++L + EE+I++++  K L+++    + +V  ++  P+ +G   E +D N AIV
Sbjct: 51  KLERIKDYLLMVEEFIRNQEQIKLLEEKQEEGRSKVDDLRGTPMSVGNLEEIIDDNHAIV 110

Query: 104 GSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVM 163
            ++ GS +Y  I+S ++++LL+P  S+ L    +A++ VL  +    + M+  ++ P   
Sbjct: 111 STSVGSEHYDSIISFVEKDLLEPGCSILLRHKVHAVIGVLMDDTGPLVTMMKVEKAPQET 170

Query: 164 YADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHT 223
           Y + GG+D Q QE++E++ELPL H E Y+++G  PP+GV++ GPPG              
Sbjct: 171 YVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPG-------------- 216

Query: 224 TAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADR 283
           TA F+RVVGSE +QKYLG+GP++VR VF++A+E+AP+I+F DEI+AI TKR+D+ +G +R
Sbjct: 217 TATFLRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGER 276

Query: 284 EVQRILLEL--LNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQK 341
           E+Q+ +LEL  LNQ+ GFD   +VKVIMAT + +TLDP L+RPGR+D+KIEF LPD + K
Sbjct: 277 EIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKTK 336

Query: 342 RLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEK 401
           + IF   TS+M L+ +V L+D +   D  SGADI +IC E+G++A+RE+R     +DF+K
Sbjct: 337 KHIFQIHTSRMTLANDVTLDDLIMAKDDFSGADIKAICTEAGLMALREHRMKATNEDFKK 396

Query: 402 AYKTVIKKDEQ 412
           + ++V+ K  +
Sbjct: 397 SIESVLYKKHE 407


>gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens]
          Length = 439

 Score =  316 bits (810), Expect = 2e-86
 Identities = 159/400 (39%), Positives = 246/400 (61%), Gaps = 20/400 (5%)

Query: 38  EDLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVD 97
           E++  R + L  E++ ++ +   +  E + +K +     E++K  +++P ++   +E +D
Sbjct: 39  EEIIQRTRLLDSEIKIMKSEVLRVTHELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLD 98

Query: 98  QNT--------------------AIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSN 137
            +                     A++ ++T   Y++ ++  +D E LKP   V ++K S 
Sbjct: 99  VDPNDQEEDGANIDLDSQRKGKCAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSY 158

Query: 138 ALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGID 197
            +++ LP E DS +  +  D++P   Y+DIGG+D Q QE+ EA+ LP+ H E ++ +GI 
Sbjct: 159 LILETLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQ 218

Query: 198 PPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKEN 257
           PP+GVLMYGPPG GKT+LA+A A  T A F+++ G + VQ ++G+G ++VRD F LAKE 
Sbjct: 219 PPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEK 278

Query: 258 APAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTL 317
           AP+IIFIDE+DAI TKRFD++   DREVQR +LELLNQ+DGF  N  VKVI ATNR D L
Sbjct: 279 APSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNTQVKVIAATNRVDIL 338

Query: 318 DPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINS 377
           DPALLR GRLDRKIEFP+P+   +  I    + KMN+S +V+ E+     D  +GA   +
Sbjct: 339 DPALLRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKA 398

Query: 378 ICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFY 417
           +C E+GM+A+R     +  +D+ +    V  K +   ++Y
Sbjct: 399 VCVEAGMIALRRGATELTHEDYMEGILEVQAKKKANLQYY 438


>gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens]
          Length = 406

 Score =  316 bits (809), Expect = 3e-86
 Identities = 170/396 (42%), Positives = 247/396 (62%), Gaps = 14/396 (3%)

Query: 31  GPEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQ------------EE 78
           GPE  +LE+  +     Q  L  +E  +  + D+ +NL++  L AQ            EE
Sbjct: 5   GPEQMELEEGKAGSGLRQYYLSKIEELQLIVNDKSQNLRR--LQAQRNELNAKVRLLREE 62

Query: 79  VKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNA 138
           ++ +Q     +G+ + A+D+   +V       + V +   ID   + PN  VAL   S  
Sbjct: 63  LQLLQEQGSYVGEVVRAMDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYT 122

Query: 139 LVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDP 198
           L  +LP + D  + ++  ++ PD  Y  IGG+D Q +E++E +ELP+ H EL++ +GI  
Sbjct: 123 LHKILPNKVDPLVSLMMVEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQ 182

Query: 199 PRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENA 258
           P+GVL+YGPPG GKT+LA+AVAHHT   FIRV GSE VQK++GEG RMVR++F +A+E+A
Sbjct: 183 PKGVLLYGPPGTGKTLLARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHA 242

Query: 259 PAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLD 318
           P+IIF+DEID+I + R +  +G D EVQR +LELLNQ+DGF+   N+KVIMATNR D LD
Sbjct: 243 PSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILD 302

Query: 319 PALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSI 378
            ALLRPGR+DRKIEFP P+   +  I    + KMNL+  ++L          SGA++  +
Sbjct: 303 SALLRPGRIDRKIEFPPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGV 362

Query: 379 CQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEH 414
           C E+GM A+RE R  V  +DFE A   V++KD +++
Sbjct: 363 CTEAGMYALRERRVHVTQEDFEMAVAKVMQKDSEKN 398


>gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens]
          Length = 403

 Score =  306 bits (783), Expect = 3e-83
 Identities = 158/382 (41%), Positives = 241/382 (63%), Gaps = 4/382 (1%)

Query: 32  PEPEDLEDLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQ 91
           P  + L+D    Y+K   E + ++ + + ++++ K L K++  ++ ++K +QS+  ++G+
Sbjct: 18  PRDKALQD----YRKKLLEHKEIDGRLKELREQLKELTKQYEKSENDLKALQSVGQIVGE 73

Query: 92  FLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSI 151
            L+ + +   IV +T G  Y V     +D+  LKP   VAL   +  ++  LP E D  +
Sbjct: 74  VLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLV 133

Query: 152 MMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCG 211
             ++ +   +V Y++IGG+  Q +E+RE +ELPLT+ EL++++GI PP+G L+YGPPG G
Sbjct: 134 YNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTG 193

Query: 212 KTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIA 271
           KT+LA+AVA      F++VV S  V KY+GE  R++R++F  A+++ P IIF+DEIDAI 
Sbjct: 194 KTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIG 253

Query: 272 TKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKI 331
            +RF   T ADRE+QR L+ELLNQMDGFD    VK+IMATNR DTLDPALLRPGRLDRKI
Sbjct: 254 GRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKI 313

Query: 332 EFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENR 391
              LP+ + +  I       +    E+D E  V   D  +GAD+ ++C E+GM A+R + 
Sbjct: 314 HIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADH 373

Query: 392 YIVLAKDFEKAYKTVIKKDEQE 413
             V+ +DF KA + V    + E
Sbjct: 374 DFVVQEDFMKAVRKVADSKKLE 395


>gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens]
          Length = 433

 Score =  285 bits (729), Expect = 5e-77
 Identities = 140/266 (52%), Positives = 184/266 (69%)

Query: 143 LPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGV 202
           LPP+ D ++ M+  ++KPDV Y+D+GG   Q +++RE VE PL H E +  +GI+PP+GV
Sbjct: 153 LPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGV 212

Query: 203 LMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAII 262
           L++GPPG GKT+ A+AVA+ T A FIRV+GSE VQKY+GEG RMVR++F +A+     +I
Sbjct: 213 LLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLI 272

Query: 263 FIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALL 322
           F DEIDAI   RFD   G D EVQR +LEL+NQ+DGFD   N+KV+MATNR DTLDPAL+
Sbjct: 273 FFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALM 332

Query: 323 RPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQES 382
           RPGRLDRKIEF LPD   +  IF      M++  ++  E         +GA+I S+C E+
Sbjct: 333 RPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEA 392

Query: 383 GMLAVRENRYIVLAKDFEKAYKTVIK 408
           GM A+R  R I   KDF +A   VIK
Sbjct: 393 GMFAIRARRKIATEKDFLEAVNKVIK 418


>gi|157671927 spermatogenesis associated 5 [Homo sapiens]
          Length = 893

 Score =  223 bits (568), Expect = 3e-58
 Identities = 120/292 (41%), Positives = 183/292 (62%), Gaps = 9/292 (3%)

Query: 130 VALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFE 189
           + L     A+ D+ P     S M   +   P+V ++DIGG++  K ++ +AVE PL H E
Sbjct: 597 ITLKDFLQAMNDIRP-----SAMREIAIDVPNVSWSDIGGLESIKLKLEQAVEWPLKHPE 651

Query: 190 LYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRD 249
            + ++GI PP+GVL+YGPPGC KTM+AKA+A+ +   F+ + G E + KY+GE  R VR+
Sbjct: 652 SFIRMGIQPPKGVLLYGPPGCSKTMIAKALANESGLNFLAIKGPELMNKYVGESERAVRE 711

Query: 250 VFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIM 309
            FR A+  AP+IIF DE+DA+A +R  +  GA     R+L +LL +MDG +Q  +V ++ 
Sbjct: 712 TFRKARAVAPSIIFFDELDALAVER-GSSLGAGNVADRVLAQLLTEMDGIEQLKDVTILA 770

Query: 310 ATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDK 369
           ATNR D +D AL+RPGR+DR I  PLPD   +R IF      M +S EVDL++ + + D 
Sbjct: 771 ATNRPDRIDKALMRPGRIDRIIYVPLPDAATRREIFKLQFHSMPVSNEVDLDELILQTDA 830

Query: 370 ISGADINSICQESGMLAVREN--RYIVLAKDFEKAYKTVIKK-DEQEHEFYK 418
            SGA+I ++C+E+ +LA+ E+    +++ + F +A  TV  +  E    FY+
Sbjct: 831 YSGAEIVAVCREAALLALEEDIQANLIMKRHFTQALSTVTPRIPESLRRFYE 882



 Score =  162 bits (410), Expect = 5e-40
 Identities = 95/236 (40%), Positives = 135/236 (57%), Gaps = 7/236 (2%)

Query: 157 DQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLA 216
           D +  V Y  IGG+  Q + +RE +ELPL   EL+K  GI  PRGVL+YGPPG GKTM+A
Sbjct: 345 DNQFKVTYDMIGGLSSQLKAIREIIELPLKQPELFKSYGIPAPRGVLLYGPPGTGKTMIA 404

Query: 217 KAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFD 276
           +AVA+   A    + G E + K+ GE    +R +F  A    P+IIFIDE+DA+  KR  
Sbjct: 405 RAVANEVGAYVSVINGPEIISKFYGETEAKLRQIFAEATLRHPSIIFIDELDALCPKREG 464

Query: 277 AQTGADREVQRILLELLNQMDGFDQNVN---VKVIMATNRADTLDPALLRPGRLDRKIEF 333
           AQ   ++   R++  LL  MDG    V+   V V+ ATNR   LD AL RPGR D++IE 
Sbjct: 465 AQNEVEK---RVVASLLTLMDGIGSEVSEGQVLVLGATNRPHALDAALRRPGRFDKEIEI 521

Query: 334 PLPDRRQKRLIFSTITSKM-NLSEEVDLEDYVARPDKISGADINSICQESGMLAVR 388
            +P+ + +  I   +  ++ +L  E +L           GAD+  +C E+G+ A+R
Sbjct: 522 GVPNAQDRLDILQKLLRRVPHLLTEAELLQLANSAHGYVGADLKVLCNEAGLCALR 577


>gi|6005942 valosin-containing protein [Homo sapiens]
          Length = 806

 Score =  195 bits (496), Expect = 6e-50
 Identities = 98/245 (40%), Positives = 150/245 (61%)

Query: 146 EADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMY 205
           +++ S +  T  + P V + DIGG++  K+E++E V+ P+ H + + + G+ P +GVL Y
Sbjct: 458 QSNPSALRETVVEVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFY 517

Query: 206 GPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFID 265
           GPPGCGKT+LAKA+A+   A FI + G E +  + GE    VR++F  A++ AP ++F D
Sbjct: 518 GPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFD 577

Query: 266 EIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPG 325
           E+D+IA  R            R++ ++L +MDG     NV +I ATNR D +DPA+LRPG
Sbjct: 578 ELDSIAKARGGNIGDGGGAADRVINQILTEMDGMSTKKNVFIIGATNRPDIIDPAILRPG 637

Query: 326 RLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGML 385
           RLD+ I  PLPD + +  I      K  ++++VDLE      +  SGAD+  ICQ +  L
Sbjct: 638 RLDQLIYIPLPDEKSRVAILKANLRKSPVAKDVDLEFLAKMTNGFSGADLTEICQRACKL 697

Query: 386 AVREN 390
           A+RE+
Sbjct: 698 AIRES 702



 Score =  195 bits (495), Expect = 7e-50
 Identities = 104/238 (43%), Positives = 148/238 (62%), Gaps = 3/238 (1%)

Query: 161 DVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVA 220
           +V Y DIGG   Q  +++E VELPL H  L+K IG+ PPRG+L+YGPPG GKT++A+AVA
Sbjct: 200 EVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVA 259

Query: 221 HHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTG 280
           + T A F  + G E + K  GE    +R  F  A++NAPAIIFIDE+DAIA KR      
Sbjct: 260 NETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGE 319

Query: 281 ADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQ 340
            +R   RI+ +LL  MDG  Q  +V V+ ATNR +++DPAL R GR DR+++  +PD   
Sbjct: 320 VER---RIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATG 376

Query: 341 KRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKD 398
           +  I    T  M L+++VDLE          GAD+ ++C E+ + A+R+   ++  +D
Sbjct: 377 RLEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAALQAIRKKMDLIDLED 434


>gi|5802970 AFG3 ATPase family gene 3-like 2 [Homo sapiens]
          Length = 797

 Score =  186 bits (472), Expect = 3e-47
 Identities = 104/252 (41%), Positives = 148/252 (58%), Gaps = 7/252 (2%)

Query: 161 DVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVA 220
           DV + D+ G +  K E+ E V   L + + Y+ +G   P+G ++ GPPG GKT+LAKA A
Sbjct: 304 DVKFKDVAGCEEAKLEIMEFVNF-LKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATA 362

Query: 221 HHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTG 280
                 FI V GSEF++ ++G GP  VRD+F LA++NAP I+FIDEIDA+  KR     G
Sbjct: 363 GEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFG 422

Query: 281 ADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQ 340
              E +  L +LL +MDGF+   NV ++  TNR D LDPALLRPGR DR+I    PD + 
Sbjct: 423 GQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKG 482

Query: 341 KRLIFSTITSKMNLSEEVDLEDYVAR-----PDKISGADINSICQESGMLAVRENRYIVL 395
           +  IF      + L   ++ +D +AR         SGAD+ ++C E+ ++A R     + 
Sbjct: 483 RASIFKVHLRPLKLDSTLE-KDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDSIN 541

Query: 396 AKDFEKAYKTVI 407
            K FE+A + VI
Sbjct: 542 QKHFEQAIERVI 553


>gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]
          Length = 750

 Score =  185 bits (470), Expect = 6e-47
 Identities = 108/276 (39%), Positives = 166/276 (60%), Gaps = 23/276 (8%)

Query: 160 PDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAV 219
           P+V +ADIG ++  ++E+  A+  P+ + + +K +G+  P GVL+ GPPGCGKT+LAKAV
Sbjct: 470 PNVTWADIGALEDIREELTMAILAPVRNPDQFKALGLVTPAGVLLAGPPGCGKTLLAKAV 529

Query: 220 AHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQT 279
           A+ +   FI V G E +  Y+GE  R VR VF+ AK +AP +IF DE+DA+  +R D +T
Sbjct: 530 ANESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDALCPRRSDRET 589

Query: 280 GADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRR 339
           GA     R++ +LL +MDG +    V ++ ATNR D +DPA+LRPGRLD+ +   LP   
Sbjct: 590 GAS---VRVVNQLLTEMDGLEARQQVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPPPA 646

Query: 340 QKRLIFSTIT---SKMNLSEEVDLEDYVA--RPDKISGADINSICQESGMLAVRE----- 389
            +  I  TIT   +K  L  +V+LE      R D  +GAD++++ +E+ + A+R+     
Sbjct: 647 DRLAILKTITKNGTKPPLDADVNLEAIAGDLRCDCYTGADLSALVREASICALRQEMARQ 706

Query: 390 ------NRYIVLAKDFEKAYK----TVIKKDEQEHE 415
                     V  K FE+A+K    ++ KKD+  +E
Sbjct: 707 KSGNEKGELKVSHKHFEEAFKKVRSSISKKDQIMYE 742



 Score =  167 bits (424), Expect = 1e-41
 Identities = 94/244 (38%), Positives = 139/244 (56%), Gaps = 3/244 (1%)

Query: 158 QKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAK 217
           Q  +V + D+GG D+  +EV + + + + H E+Y  +G+ PPRGVL++GPPGCGKT+LA 
Sbjct: 152 QISNVKFEDVGGNDMTLKEVCKML-IHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAH 210

Query: 218 AVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDA 277
           A+A       ++V   E V    GE  + +R++F  A  NAP IIFIDEIDAI  KR  A
Sbjct: 211 AIAGELDLPILKVAAPEIVSGVSGESEQKLRELFEQAVSNAPCIIFIDEIDAITPKREVA 270

Query: 278 QTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPD 337
               +R +   LL  ++ ++       V VI ATNR D+LDPAL R GR DR+I   +PD
Sbjct: 271 SKDMERRIVAQLLTCMDDLNNVAATARVLVIGATNRPDSLDPALRRAGRFDREICLGIPD 330

Query: 338 RRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAK 397
              +  I  T+  K+ L +  D            GAD+ ++C+E+ M AV  NR ++  +
Sbjct: 331 EASRERILQTLCRKLRLPQAFDFCHLAHLTPGFVGADLMALCREAAMCAV--NRVLMKLQ 388

Query: 398 DFEK 401
           + +K
Sbjct: 389 EQQK 392


>gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]
          Length = 856

 Score =  185 bits (470), Expect = 6e-47
 Identities = 108/276 (39%), Positives = 166/276 (60%), Gaps = 23/276 (8%)

Query: 160 PDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAV 219
           P+V +ADIG ++  ++E+  A+  P+ + + +K +G+  P GVL+ GPPGCGKT+LAKAV
Sbjct: 576 PNVTWADIGALEDIREELTMAILAPVRNPDQFKALGLVTPAGVLLAGPPGCGKTLLAKAV 635

Query: 220 AHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQT 279
           A+ +   FI V G E +  Y+GE  R VR VF+ AK +AP +IF DE+DA+  +R D +T
Sbjct: 636 ANESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDALCPRRSDRET 695

Query: 280 GADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRR 339
           GA     R++ +LL +MDG +    V ++ ATNR D +DPA+LRPGRLD+ +   LP   
Sbjct: 696 GAS---VRVVNQLLTEMDGLEARQQVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPPPA 752

Query: 340 QKRLIFSTIT---SKMNLSEEVDLEDYVA--RPDKISGADINSICQESGMLAVRE----- 389
            +  I  TIT   +K  L  +V+LE      R D  +GAD++++ +E+ + A+R+     
Sbjct: 753 DRLAILKTITKNGTKPPLDADVNLEAIAGDLRCDCYTGADLSALVREASICALRQEMARQ 812

Query: 390 ------NRYIVLAKDFEKAYK----TVIKKDEQEHE 415
                     V  K FE+A+K    ++ KKD+  +E
Sbjct: 813 KSGNEKGELKVSHKHFEEAFKKVRSSISKKDQIMYE 848



 Score =  167 bits (424), Expect = 1e-41
 Identities = 94/244 (38%), Positives = 139/244 (56%), Gaps = 3/244 (1%)

Query: 158 QKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAK 217
           Q  +V + D+GG D+  +EV + + + + H E+Y  +G+ PPRGVL++GPPGCGKT+LA 
Sbjct: 258 QISNVKFEDVGGNDMTLKEVCKML-IHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAH 316

Query: 218 AVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDA 277
           A+A       ++V   E V    GE  + +R++F  A  NAP IIFIDEIDAI  KR  A
Sbjct: 317 AIAGELDLPILKVAAPEIVSGVSGESEQKLRELFEQAVSNAPCIIFIDEIDAITPKREVA 376

Query: 278 QTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPD 337
               +R +   LL  ++ ++       V VI ATNR D+LDPAL R GR DR+I   +PD
Sbjct: 377 SKDMERRIVAQLLTCMDDLNNVAATARVLVIGATNRPDSLDPALRRAGRFDREICLGIPD 436

Query: 338 RRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAK 397
              +  I  T+  K+ L +  D            GAD+ ++C+E+ M AV  NR ++  +
Sbjct: 437 EASRERILQTLCRKLRLPQAFDFCHLAHLTPGFVGADLMALCREAAMCAV--NRVLMKLQ 494

Query: 398 DFEK 401
           + +K
Sbjct: 495 EQQK 498


>gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens]
          Length = 753

 Score =  174 bits (441), Expect = 1e-43
 Identities = 104/286 (36%), Positives = 167/286 (58%), Gaps = 25/286 (8%)

Query: 143 LPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGV 202
           + P +  S++ L  D KP V + +IGG++  K ++++++E PL     + ++G+  P+GV
Sbjct: 444 IQPSSFRSVIGLM-DIKP-VDWEEIGGLEDVKLKLKQSIEWPLKFPWEFVRMGLTQPKGV 501

Query: 203 LMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAII 262
           L+YGPPGC KT L +A+A     +F+ V G++    ++G+  +++  +FR A+ + PAI+
Sbjct: 502 LLYGPPGCAKTTLVRALATSCHCSFVSVSGADLFSPFVGDSEKVLSQIFRQARASTPAIL 561

Query: 263 FIDEIDAIATKRFDAQTGADREVQRILLELLNQMDG-----------------FDQ--NV 303
           F+DEID+I   R  ++TG D + +R+L  LLN++DG                 F +  N 
Sbjct: 562 FLDEIDSILGARSASKTGCDVQ-ERVLSVLLNELDGVGLKTIERRGSKSSQQEFQEVFNR 620

Query: 304 NVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDY 363
           +V +I ATNR D LD ALLRPGRLD+ I  P PD + +  I    T  M +  +V LE+ 
Sbjct: 621 SVMIIAATNRPDVLDTALLRPGRLDKIIYIPPPDHKGRLSILKVCTKTMPIGPDVSLENL 680

Query: 364 VARPDKISGADINSICQESGMLAVREN---RYIVLAKDFEKAYKTV 406
            A     SGAD+ ++C E+ +LA++EN      V  + F K+ KTV
Sbjct: 681 AAETCFFSGADLRNLCTEAALLALQENGLDATTVKQEHFLKSLKTV 726



 Score =  145 bits (366), Expect = 7e-35
 Identities = 88/248 (35%), Positives = 134/248 (54%), Gaps = 13/248 (5%)

Query: 167 IGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAA 226
           +GG+      +RE + LPL +      +G+  PRGVL+ GPPG GKT L +AVA    A 
Sbjct: 202 LGGLSEAADSLRELLRLPLRYPRALTALGLAVPRGVLLAGPPGVGKTQLVRAVAREAGAE 261

Query: 227 FIRVVGSEFVQKYLGEGPRMVRDVFRLAKENA---PAIIFIDEIDAIATKRFDAQTGADR 283
            + V          GE    VR VF+ A+E A   P+++F+DE+DA+  +R     G+  
Sbjct: 262 LLAVSAPALQGSRPGETEENVRRVFQRARELASRGPSLLFLDEMDALCPQR-----GSRA 316

Query: 284 EVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRL 343
              R++ ++L  +DG   +  V V+ ATNR D LDPAL RPGR DR++    P  +Q++ 
Sbjct: 317 PESRVVAQVLTLLDGASGDREVVVVGATNRPDALDPALRRPGRFDREVVIGTPTLKQRKE 376

Query: 344 IFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAV-----RENRYIVLAKD 398
           I   ITSKM +S  VDL           GAD+ ++C+E+ M A+      ++  ++   D
Sbjct: 377 ILQVITSKMPISSHVDLGLLAEMTVGYVGADLTALCREAAMHALLHSEKNQDNPVIDEID 436

Query: 399 FEKAYKTV 406
           F +A+K +
Sbjct: 437 FLEAFKNI 444


>gi|4507173 spastic paraplegia 7 isoform 1 [Homo sapiens]
          Length = 795

 Score =  170 bits (430), Expect = 3e-42
 Identities = 101/249 (40%), Positives = 143/249 (57%), Gaps = 4/249 (1%)

Query: 162 VMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAH 221
           V + D+ GM   K EVRE V+  L   E + Q+G   P+G L+ GPPGCGKT+LAKAVA 
Sbjct: 306 VSFKDVAGMHEAKLEVREFVDY-LKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVAT 364

Query: 222 HTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTG- 280
                F+ + G EFV+   G G   VR +F+ A+  AP I++IDEIDA+  KR    +G 
Sbjct: 365 EAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGF 424

Query: 281 ADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQ 340
           ++ E ++ L +LL +MDG     +V V+ +TNRAD LD AL+RPGRLDR +   LP  ++
Sbjct: 425 SNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLPTLQE 484

Query: 341 KRLIFSTITSKMNLSEEVDL--EDYVARPDKISGADINSICQESGMLAVRENRYIVLAKD 398
           +R IF      + L++      +         SGADI +IC E+ + A RE    V   +
Sbjct: 485 RREIFEQHLKSLKLTQSSTFYSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTLN 544

Query: 399 FEKAYKTVI 407
           FE A + V+
Sbjct: 545 FEYAVERVL 553


>gi|4505725 peroxin1 [Homo sapiens]
          Length = 1283

 Score =  157 bits (398), Expect = 1e-38
 Identities = 83/239 (34%), Positives = 140/239 (58%), Gaps = 3/239 (1%)

Query: 149  SSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPP 208
            +S+  +   +  D+ +  IGG+   +Q + + ++LP  + EL+  + I    G+L+YGPP
Sbjct: 824  ASLRSVNLHKPRDLGWDKIGGLHEVRQILMDTIQLPAKYPELFANLPIRQRTGILLYGPP 883

Query: 209  GCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEID 268
            G GKT+LA  +A  +   FI V G E + KY+G   + VRD+F  A+   P I+F DE +
Sbjct: 884  GTGKTLLAGVIARESRMNFISVKGPELLSKYIGASEQAVRDIFIRAQAAKPCILFFDEFE 943

Query: 269  AIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLD 328
            +IA +R    TG      R++ +LL Q+DG +    V V+ AT+R D +DPALLRPGRLD
Sbjct: 944  SIAPRRGHDNTGV---TDRVVNQLLTQLDGVEGLQGVYVLAATSRPDLIDPALLRPGRLD 1000

Query: 329  RKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAV 387
            + +  P PD+  +  I + ++  + L+++VDL+   +  D  +GAD+ ++   + + A+
Sbjct: 1001 KCVYCPPPDQVSRLEILNVLSDSLPLADDVDLQHVASVTDSFTGADLKALLYNAQLEAL 1059


>gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]
          Length = 980

 Score =  157 bits (397), Expect = 2e-38
 Identities = 93/232 (40%), Positives = 140/232 (60%), Gaps = 7/232 (3%)

Query: 160 PDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAV 219
           P V + D+GG+   K+E+ E ++LPL H EL   +G+    G+L++GPPG GKT+LAKAV
Sbjct: 700 PSVSWHDVGGLQEVKKEILETIQLPLEHPELLS-LGLRRS-GLLLHGPPGTGKTLLAKAV 757

Query: 220 AHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQT 279
           A   +  F+ V G E +  Y+G+    VR+VF  A+  AP IIF DE+D++A  R   ++
Sbjct: 758 ATECSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSR--GRS 815

Query: 280 GADREV-QRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDR 338
           G    V  R++ +LL ++DG     +V VI ATNR D LDPALLRPGR D+ +     + 
Sbjct: 816 GDSGGVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLRPGRFDKLVFVGANED 875

Query: 339 RQKRL-IFSTITSKMNLSEEVDLEDYV-ARPDKISGADINSICQESGMLAVR 388
           R  +L + S IT K  L   V L + +   P +++GAD+ S+C ++   A++
Sbjct: 876 RASQLRVLSAITRKFKLEPSVSLVNVLDCCPPQLTGADLYSLCSDAMTAALK 927



 Score = 63.5 bits (153), Expect = 3e-10
 Identities = 48/185 (25%), Positives = 80/185 (43%), Gaps = 4/185 (2%)

Query: 202 VLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAI 261
           VL+ GPPGCGKT +  A   H     ++V  S    +  G     ++ +F  A+   PA+
Sbjct: 466 VLLRGPPGCGKTTVVAAACSHLGLHLLKVPCSSLCAESSGAVETKLQAIFSRARRCRPAV 525

Query: 262 IFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPAL 321
           + +  +D +   R     G D  V  +L  LL   D  +    + V+  T+RA  L PA 
Sbjct: 526 LLLTAVDLLGRDR--DGLGEDARVMAVLRHLLLNEDPLNSCPPLMVVATTSRAQDL-PAD 582

Query: 322 LRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQE 381
           ++      ++E P     Q+  I   +T+ + L +EV+L     R       D+ ++   
Sbjct: 583 VQTA-FPHELEVPALSEGQRLSILRALTAHLPLGQEVNLAQLARRCAGFVVGDLYALLTH 641

Query: 382 SGMLA 386
           S   A
Sbjct: 642 SSRAA 646


>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
          Length = 1390

 Score =  155 bits (392), Expect = 6e-38
 Identities = 104/297 (35%), Positives = 152/297 (51%), Gaps = 36/297 (12%)

Query: 138 ALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGID 197
           +L DV P + DSS           V +  +GG+      ++E V  PL + E++++  I 
Sbjct: 410 SLADVDPMQLDSS-----------VRFDSVGGLSNHIAALKEMVVFPLLYPEVFEKFKIQ 458

Query: 198 PPRGVLMYGPPGCGKTMLAKAVAHHTT-----AAFIRVVGSEFVQKYLGEGPRMVRDVFR 252
           PPRG L YGPPG GKT++A+A+A+  +      AF    G++ + K++GE  R +R +F 
Sbjct: 459 PPRGCLFYGPPGTGKTLVARALANECSQGDKRVAFFMRKGADCLSKWVGESERQLRLLFD 518

Query: 253 LAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATN 312
            A +  P+IIF DEID +A  R   Q   D+    I+  LL  MDG D    + VI ATN
Sbjct: 519 QAYQMRPSIIFFDEIDGLAPVRSSRQ---DQIHSSIVSTLLALMDGLDSRGEIVVIGATN 575

Query: 313 RADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSE-EVDLEDYVARPDKIS 371
           R D++DPAL RPGR DR+  F LPD+  ++ I    T   N    +  LE+         
Sbjct: 576 RLDSIDPALRRPGRFDREFLFSLPDKEARKEILKIHTRDWNPKPLDTFLEELAENCVGYC 635

Query: 372 GADINSICQESGMLAVRE----------------NRYIVLAKDFEKAYKTVIKKDEQ 412
           GADI SIC E+ + A+R                 +   + AKDFE A + +I   ++
Sbjct: 636 GADIKSICAEAALCALRRRYPQIYTTSEKLQLDLSSINISAKDFEVAMQKMIPASQR 692


>gi|21327685 YME1-like 1 isoform 1 [Homo sapiens]
          Length = 773

 Score =  152 bits (383), Expect = 7e-37
 Identities = 86/255 (33%), Positives = 144/255 (56%), Gaps = 3/255 (1%)

Query: 158 QKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAK 217
           Q  +V +  + G++  KQE++E VE  L + + +  +G   P+G+L+ GPPG GKT+LA+
Sbjct: 332 QMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLAR 390

Query: 218 AVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDA 277
           AVA      F    GSEF + ++G G   +R++FR AK NAP +IFIDE+D++  KR ++
Sbjct: 391 AVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIES 450

Query: 278 QTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPD 337
                   ++ + +LL +MDGF  N  V +I ATN  + LD AL+RPGR D ++  P PD
Sbjct: 451 P--MHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPD 508

Query: 338 RRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAK 397
            + +  I     +K+   + VD E         SGA++ ++  ++ + A  + + +V  K
Sbjct: 509 VKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMK 568

Query: 398 DFEKAYKTVIKKDEQ 412
           + E +   ++   E+
Sbjct: 569 ELEFSKDKILMGPER 583


>gi|7657689 YME1-like 1 isoform 3 [Homo sapiens]
          Length = 716

 Score =  152 bits (383), Expect = 7e-37
 Identities = 86/255 (33%), Positives = 144/255 (56%), Gaps = 3/255 (1%)

Query: 158 QKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAK 217
           Q  +V +  + G++  KQE++E VE  L + + +  +G   P+G+L+ GPPG GKT+LA+
Sbjct: 275 QMKNVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLAR 333

Query: 218 AVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDA 277
           AVA      F    GSEF + ++G G   +R++FR AK NAP +IFIDE+D++  KR ++
Sbjct: 334 AVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIES 393

Query: 278 QTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPD 337
                   ++ + +LL +MDGF  N  V +I ATN  + LD AL+RPGR D ++  P PD
Sbjct: 394 P--MHPYSRQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPD 451

Query: 338 RRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAK 397
            + +  I     +K+   + VD E         SGA++ ++  ++ + A  + + +V  K
Sbjct: 452 VKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMK 511

Query: 398 DFEKAYKTVIKKDEQ 412
           + E +   ++   E+
Sbjct: 512 ELEFSKDKILMGPER 526


>gi|31742536 fidgetin-like 1 [Homo sapiens]
          Length = 674

 Score =  151 bits (381), Expect = 1e-36
 Identities = 95/280 (33%), Positives = 152/280 (54%), Gaps = 23/280 (8%)

Query: 143 LPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGV 202
           L P+    IM    D  P V + DI G++  K  ++E V  P+   +++  +   PP+G+
Sbjct: 379 LEPKMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLR-GPPKGI 437

Query: 203 LMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAII 262
           L++GPPG GKT++ K +A  + A F  +  S    K++GEG +MVR +F +A+   PA+I
Sbjct: 438 LLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVI 497

Query: 263 FIDEIDAIATKRFDAQTGADREVQRILLELLNQMDG--FDQNVNVKVIMATNRADTLDPA 320
           FIDEID++ ++R D +  + R   RI  E L Q+DG        + V+ ATNR   +D A
Sbjct: 498 FIDEIDSLLSQRGDGEHESSR---RIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEA 554

Query: 321 LLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMN--LSEEVDLEDYVARPDKISGADINSI 378
             R  RL +++  PLP+   ++ I   + SK    LSEE ++E  V + D  SGAD+  +
Sbjct: 555 ARR--RLVKRLYIPLPEASARKQIVINLMSKEQCCLSEE-EIEQIVQQSDAFSGADMTQL 611

Query: 379 CQESGMLAVRENRYIVLAK------------DFEKAYKTV 406
           C+E+ +  +R  +   +A             DFE A++TV
Sbjct: 612 CREASLGPIRSLQTADIATITPDQVRPIAYIDFENAFRTV 651


>gi|112789543 fidgetin-like 1 [Homo sapiens]
          Length = 674

 Score =  151 bits (381), Expect = 1e-36
 Identities = 95/280 (33%), Positives = 152/280 (54%), Gaps = 23/280 (8%)

Query: 143 LPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGV 202
           L P+    IM    D  P V + DI G++  K  ++E V  P+   +++  +   PP+G+
Sbjct: 379 LEPKMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLR-GPPKGI 437

Query: 203 LMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAII 262
           L++GPPG GKT++ K +A  + A F  +  S    K++GEG +MVR +F +A+   PA+I
Sbjct: 438 LLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVI 497

Query: 263 FIDEIDAIATKRFDAQTGADREVQRILLELLNQMDG--FDQNVNVKVIMATNRADTLDPA 320
           FIDEID++ ++R D +  + R   RI  E L Q+DG        + V+ ATNR   +D A
Sbjct: 498 FIDEIDSLLSQRGDGEHESSR---RIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEA 554

Query: 321 LLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMN--LSEEVDLEDYVARPDKISGADINSI 378
             R  RL +++  PLP+   ++ I   + SK    LSEE ++E  V + D  SGAD+  +
Sbjct: 555 ARR--RLVKRLYIPLPEASARKQIVINLMSKEQCCLSEE-EIEQIVQQSDAFSGADMTQL 611

Query: 379 CQESGMLAVRENRYIVLAK------------DFEKAYKTV 406
           C+E+ +  +R  +   +A             DFE A++TV
Sbjct: 612 CREASLGPIRSLQTADIATITPDQVRPIAYIDFENAFRTV 651


>gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens]
          Length = 1458

 Score =  150 bits (378), Expect = 3e-36
 Identities = 101/280 (36%), Positives = 147/280 (52%), Gaps = 29/280 (10%)

Query: 115 ILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQK 174
           + S I RE +K  AS+A         DV P   D S           V +  IGG+    
Sbjct: 370 LASGILRERVKVGASLA---------DVDPMNIDKS-----------VRFDSIGGLSHHI 409

Query: 175 QEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTT-----AAFIR 229
             ++E V  PL + E++++  I PPRG L YGPPG GKT++A+A+A+  +      AF  
Sbjct: 410 HALKEMVVFPLLYPEIFEKFKIQPPRGCLFYGPPGTGKTLVARALANECSQGDKKVAFFM 469

Query: 230 VVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRIL 289
             G++ + K++GE  R +R +F  A    P+IIF DEID +A  R   Q   D+    I+
Sbjct: 470 RKGADCLSKWVGESERQLRLLFDQAYLMRPSIIFFDEIDGLAPVRSSRQ---DQIHSSIV 526

Query: 290 LELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTIT 349
             LL  MDG D    + VI ATNR D++DPAL RPGR DR+  F LPD++ ++ I    T
Sbjct: 527 STLLALMDGLDNRGEIVVIGATNRLDSIDPALRRPGRFDREFLFNLPDQKARKHILQIHT 586

Query: 350 SKMNLS-EEVDLEDYVARPDKISGADINSICQESGMLAVR 388
              N    +  L +   +     GADI ++C E+ ++A+R
Sbjct: 587 RDWNPKLSDAFLGELAEKCVGYCGADIKALCTEAALIALR 626


>gi|5901990 katanin p60 subunit A 1 [Homo sapiens]
          Length = 491

 Score =  144 bits (364), Expect = 1e-34
 Identities = 92/239 (38%), Positives = 137/239 (57%), Gaps = 14/239 (5%)

Query: 158 QKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAK 217
           Q P+V + DI  +   K+ ++EAV LP+   E +K I   P +GVLM GPPG GKT+LAK
Sbjct: 202 QNPNVRWDDIADLVEAKKLLKEAVVLPMWMPEFFKGIR-RPWKGVLMVGPPGTGKTLLAK 260

Query: 218 AVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDA 277
           AVA      F  V  S    KY GE  ++VR +F +A+  +PA IFIDEID+I ++R   
Sbjct: 261 AVATECKTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYSPATIFIDEIDSICSRR--- 317

Query: 278 QTGADREV-QRILLELLNQMDGF-------DQNVNVKVIMATNRADTLDPALLRPGRLDR 329
            T  + E  +R+  ELL QMDG        D +  V V+ ATN    +D AL R  RL++
Sbjct: 318 GTSEEHEASRRVKAELLVQMDGVGGTSENDDPSKMVMVLAATNFPWDIDEALRR--RLEK 375

Query: 330 KIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVR 388
           +I  PLP  + +  +      ++ L+++VDL       +  SGADI ++C+++ ++A+R
Sbjct: 376 RIYIPLPSAKGREELLRISLRELELADDVDLASIAENMEGYSGADITNVCRDASLMAMR 434


>gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens]
          Length = 490

 Score =  143 bits (360), Expect = 3e-34
 Identities = 91/239 (38%), Positives = 136/239 (56%), Gaps = 14/239 (5%)

Query: 158 QKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAK 217
           + P + + DI  ++  K+ +REAV LP+   + +K I   P +GVLM GPPG GKTMLAK
Sbjct: 201 RNPSIHWDDIADLEEAKKLLREAVVLPMWMPDFFKGIR-RPWKGVLMVGPPGTGKTMLAK 259

Query: 218 AVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDA 277
           AVA      F  V  S    KY GE  ++VR +F +A+  AP  IFIDEID+I ++R   
Sbjct: 260 AVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRR--- 316

Query: 278 QTGADREV-QRILLELLNQMDGF-------DQNVNVKVIMATNRADTLDPALLRPGRLDR 329
            T  + E  +R+  ELL QMDG        D +  V V+ ATN    +D AL R  RL++
Sbjct: 317 GTSDEHEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDEALRR--RLEK 374

Query: 330 KIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVR 388
           +I  PLP  + +  +      ++ L  ++ LED   + +  SGADI ++C+++ ++A+R
Sbjct: 375 RIYIPLPTAKGRAELLKINLREVELDPDIQLEDIAEKIEGYSGADITNVCRDASLMAMR 433


>gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens]
          Length = 490

 Score =  143 bits (360), Expect = 3e-34
 Identities = 91/239 (38%), Positives = 136/239 (56%), Gaps = 14/239 (5%)

Query: 158 QKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAK 217
           + P + + DI  ++  K+ +REAV LP+   + +K I   P +GVLM GPPG GKTMLAK
Sbjct: 201 RNPSIHWDDIADLEEAKKLLREAVVLPMWMPDFFKGIR-RPWKGVLMVGPPGTGKTMLAK 259

Query: 218 AVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDA 277
           AVA      F  V  S    KY GE  ++VR +F +A+  AP  IFIDEID+I ++R   
Sbjct: 260 AVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRR--- 316

Query: 278 QTGADREV-QRILLELLNQMDGF-------DQNVNVKVIMATNRADTLDPALLRPGRLDR 329
            T  + E  +R+  ELL QMDG        D +  V V+ ATN    +D AL R  RL++
Sbjct: 317 GTSDEHEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDEALRR--RLEK 374

Query: 330 KIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVR 388
           +I  PLP  + +  +      ++ L  ++ LED   + +  SGADI ++C+++ ++A+R
Sbjct: 375 RIYIPLPTAKGRAELLKINLREVELDPDIQLEDIAEKIEGYSGADITNVCRDASLMAMR 433


>gi|17865802 vacuolar protein sorting factor 4B [Homo sapiens]
          Length = 444

 Score =  138 bits (347), Expect = 1e-32
 Identities = 87/235 (37%), Positives = 139/235 (59%), Gaps = 9/235 (3%)

Query: 158 QKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAK 217
           ++P+V ++D+ G++  K+ ++EAV LP+    L+      P RG+L++GPPG GK+ LAK
Sbjct: 127 ERPNVKWSDVAGLEGAKEALKEAVILPIKFPHLFTGKRT-PWRGILLFGPPGTGKSYLAK 185

Query: 218 AVAHHTT-AAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFD 276
           AVA     + F  +  S+ V K+LGE  ++V+++F+LA+EN P+IIFIDEID++   R +
Sbjct: 186 AVATEANNSTFFSISSSDLVSKWLGESEKLVKNLFQLARENKPSIIFIDEIDSLCGSRSE 245

Query: 277 AQTGADREVQRILLELLNQMDGFD-QNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPL 335
            ++ A R   RI  E L QM G    N  + V+ ATN    LD A+ R  R +++I  PL
Sbjct: 246 NESEAAR---RIKTEFLVQMQGVGVDNDGILVLGATNIPWVLDSAIRR--RFEKRIYIPL 300

Query: 336 PDRRQKRLIFST-ITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRE 389
           P+   +  +F   + +  N   E D  +   + D  SGADI+ I +++ M  VR+
Sbjct: 301 PEPHARAAMFKLHLGTTQNSLTEADFRELGRKTDGYSGADISIIVRDALMQPVRK 355


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.136    0.376 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,244,032
Number of Sequences: 37866
Number of extensions: 665966
Number of successful extensions: 3641
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 104
Number of HSP's successfully gapped in prelim test: 55
Number of HSP's that attempted gapping in prelim test: 3263
Number of HSP's gapped (non-prelim): 362
length of query: 418
length of database: 18,247,518
effective HSP length: 105
effective length of query: 313
effective length of database: 14,271,588
effective search space: 4467007044
effective search space used: 4467007044
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.