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Search of human proteins with 57222563
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|57222563 colonic and hepatic tumor over-expressed protein
isoform b [Homo sapiens]
(1972 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|57222563 colonic and hepatic tumor over-expressed protein iso... 3870 0.0
gi|57164942 colonic and hepatic tumor over-expressed protein iso... 3777 0.0
gi|57863301 CLIP-associating protein 2 [Homo sapiens] 58 1e-07
gi|214010175 CLIP-associating protein 1 isoform 3 [Homo sapiens] 54 1e-06
gi|214010173 CLIP-associating protein 1 isoform 2 [Homo sapiens] 54 1e-06
gi|31563537 CLIP-associating protein 1 isoform 1 [Homo sapiens] 54 1e-06
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s... 43 0.003
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 43 0.003
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 43 0.003
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s... 43 0.003
gi|50511941 EMI domain containing 1 [Homo sapiens] 42 0.008
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 41 0.010
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 41 0.010
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 41 0.010
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 41 0.013
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 41 0.013
gi|164419758 bromodomain containing 2 [Homo sapiens] 41 0.013
gi|4826806 bromodomain containing 2 [Homo sapiens] 41 0.013
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 40 0.017
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 40 0.017
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 40 0.017
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 40 0.017
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 40 0.023
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 40 0.023
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 40 0.023
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 40 0.023
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 40 0.023
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 40 0.023
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 40 0.029
gi|187829730 BCL2 binding component 3 isoform 1 [Homo sapiens] 39 0.066
>gi|57222563 colonic and hepatic tumor over-expressed protein isoform
b [Homo sapiens]
Length = 1972
Score = 3870 bits (10035), Expect = 0.0
Identities = 1972/1972 (100%), Positives = 1972/1972 (100%)
Query: 1 MGDDSEWLKLPVDQKCEHKLWKARLSGYEEALKIFQKIKDEKSPEWSKFLGLIKKFVTDS 60
MGDDSEWLKLPVDQKCEHKLWKARLSGYEEALKIFQKIKDEKSPEWSKFLGLIKKFVTDS
Sbjct: 1 MGDDSEWLKLPVDQKCEHKLWKARLSGYEEALKIFQKIKDEKSPEWSKFLGLIKKFVTDS 60
Query: 61 NAVVQLKGLEAALVYVENAHVAGKTTGEVVSGVVSKVFNQPKAKAKELGIEICLMYIEIE 120
NAVVQLKGLEAALVYVENAHVAGKTTGEVVSGVVSKVFNQPKAKAKELGIEICLMYIEIE
Sbjct: 61 NAVVQLKGLEAALVYVENAHVAGKTTGEVVSGVVSKVFNQPKAKAKELGIEICLMYIEIE 120
Query: 121 KGEAVQEELLKGLDNKNPKIIVACIETLRKALSEFGSKIILLKPIIKVLPKLFESREKAV 180
KGEAVQEELLKGLDNKNPKIIVACIETLRKALSEFGSKIILLKPIIKVLPKLFESREKAV
Sbjct: 121 KGEAVQEELLKGLDNKNPKIIVACIETLRKALSEFGSKIILLKPIIKVLPKLFESREKAV 180
Query: 181 RDEAKLIAVEIYRWIRDALRPPLQNINSVQLKELEEEWVKLPTSAPRPTRFLRSQQELEA 240
RDEAKLIAVEIYRWIRDALRPPLQNINSVQLKELEEEWVKLPTSAPRPTRFLRSQQELEA
Sbjct: 181 RDEAKLIAVEIYRWIRDALRPPLQNINSVQLKELEEEWVKLPTSAPRPTRFLRSQQELEA 240
Query: 241 KLEQQQSAGGDAEGGGDDGDEVPQIDAYELLEAVEILSKLPKDFYDKIEAKKWQERKEAL 300
KLEQQQSAGGDAEGGGDDGDEVPQIDAYELLEAVEILSKLPKDFYDKIEAKKWQERKEAL
Sbjct: 241 KLEQQQSAGGDAEGGGDDGDEVPQIDAYELLEAVEILSKLPKDFYDKIEAKKWQERKEAL 300
Query: 301 ESVEVLIKNPKLEAGDYADLVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAG 360
ESVEVLIKNPKLEAGDYADLVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAG
Sbjct: 301 ESVEVLIKNPKLEAGDYADLVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAG 360
Query: 361 HVVPTILEKFKEKKPQVVQALQEAIDAIFLTTTLQNISEDVLAVMDNKNPTIKQQTSLFI 420
HVVPTILEKFKEKKPQVVQALQEAIDAIFLTTTLQNISEDVLAVMDNKNPTIKQQTSLFI
Sbjct: 361 HVVPTILEKFKEKKPQVVQALQEAIDAIFLTTTLQNISEDVLAVMDNKNPTIKQQTSLFI 420
Query: 421 ARSFRHCTASTLPKSLLKPFCAALLKHINDSAPEVRDAAFEALGTALKVVGEKAVNPFLA 480
ARSFRHCTASTLPKSLLKPFCAALLKHINDSAPEVRDAAFEALGTALKVVGEKAVNPFLA
Sbjct: 421 ARSFRHCTASTLPKSLLKPFCAALLKHINDSAPEVRDAAFEALGTALKVVGEKAVNPFLA 480
Query: 481 DVDKLKLDKIKECSEKVELIHGKKAGLAADKKEFKPLPGRTAASGAAGDKDTKDISAPKP 540
DVDKLKLDKIKECSEKVELIHGKKAGLAADKKEFKPLPGRTAASGAAGDKDTKDISAPKP
Sbjct: 481 DVDKLKLDKIKECSEKVELIHGKKAGLAADKKEFKPLPGRTAASGAAGDKDTKDISAPKP 540
Query: 541 GPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKGLETKEIVEPELSIEVCEEKASAVL 600
GPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKGLETKEIVEPELSIEVCEEKASAVL
Sbjct: 541 GPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKGLETKEIVEPELSIEVCEEKASAVL 600
Query: 601 PPTCIQLLDSSNWKERLACMEEFQKAVELMDRTEMPCQALVRMLAKKPGWKETNFQVMQM 660
PPTCIQLLDSSNWKERLACMEEFQKAVELMDRTEMPCQALVRMLAKKPGWKETNFQVMQM
Sbjct: 601 PPTCIQLLDSSNWKERLACMEEFQKAVELMDRTEMPCQALVRMLAKKPGWKETNFQVMQM 660
Query: 661 KLHIVALIAQKGNFSKTSAQVVLDGLVDKIGDVKCGNNAKEAMTAIAEACMLPWTAEQVV 720
KLHIVALIAQKGNFSKTSAQVVLDGLVDKIGDVKCGNNAKEAMTAIAEACMLPWTAEQVV
Sbjct: 661 KLHIVALIAQKGNFSKTSAQVVLDGLVDKIGDVKCGNNAKEAMTAIAEACMLPWTAEQVV 720
Query: 721 SMAFSQKNPKNQSETLNWLSNAIKEFGFSGLNVKAFISNVKTALAATNPAVRTAAITLLG 780
SMAFSQKNPKNQSETLNWLSNAIKEFGFSGLNVKAFISNVKTALAATNPAVRTAAITLLG
Sbjct: 721 SMAFSQKNPKNQSETLNWLSNAIKEFGFSGLNVKAFISNVKTALAATNPAVRTAAITLLG 780
Query: 781 VMYLYVGPSLRMFFEDEKPALLSQIDAEFEKMQGQSPPAPTRGISKHSTSGTDEGEDGDE 840
VMYLYVGPSLRMFFEDEKPALLSQIDAEFEKMQGQSPPAPTRGISKHSTSGTDEGEDGDE
Sbjct: 781 VMYLYVGPSLRMFFEDEKPALLSQIDAEFEKMQGQSPPAPTRGISKHSTSGTDEGEDGDE 840
Query: 841 PDDGSNDVVDLLPRTEISDKITSELVSKIGDKNWKIRKEGLDEVAGIINDAKFIQPNIGE 900
PDDGSNDVVDLLPRTEISDKITSELVSKIGDKNWKIRKEGLDEVAGIINDAKFIQPNIGE
Sbjct: 841 PDDGSNDVVDLLPRTEISDKITSELVSKIGDKNWKIRKEGLDEVAGIINDAKFIQPNIGE 900
Query: 901 LPTALKGRLNDSNKILVQQTLNILQQLAVAMGPNIKQHVKNLGIPIITVLGDSKNNVRAA 960
LPTALKGRLNDSNKILVQQTLNILQQLAVAMGPNIKQHVKNLGIPIITVLGDSKNNVRAA
Sbjct: 901 LPTALKGRLNDSNKILVQQTLNILQQLAVAMGPNIKQHVKNLGIPIITVLGDSKNNVRAA 960
Query: 961 ALATVNAWAEQTGMKEWLEGEDLSEELKKENPFLRQELLGWLAEKLPTLRSTPTDLILCV 1020
ALATVNAWAEQTGMKEWLEGEDLSEELKKENPFLRQELLGWLAEKLPTLRSTPTDLILCV
Sbjct: 961 ALATVNAWAEQTGMKEWLEGEDLSEELKKENPFLRQELLGWLAEKLPTLRSTPTDLILCV 1020
Query: 1021 PHLYSCLEDRNGDVRKKAQDALPFFMMHLGYEKMAKATGKLKPTSKDQVLAMLEKAKVNM 1080
PHLYSCLEDRNGDVRKKAQDALPFFMMHLGYEKMAKATGKLKPTSKDQVLAMLEKAKVNM
Sbjct: 1021 PHLYSCLEDRNGDVRKKAQDALPFFMMHLGYEKMAKATGKLKPTSKDQVLAMLEKAKVNM 1080
Query: 1081 PAKPAPPTKATSKPMGGSAPAKFQPASAPAEDCISSSTEPKPDPKKAKAPGLSSKAKSAQ 1140
PAKPAPPTKATSKPMGGSAPAKFQPASAPAEDCISSSTEPKPDPKKAKAPGLSSKAKSAQ
Sbjct: 1081 PAKPAPPTKATSKPMGGSAPAKFQPASAPAEDCISSSTEPKPDPKKAKAPGLSSKAKSAQ 1140
Query: 1141 GKKMPSKTSLKEDEDKSGPIFIVVPNGKEQRMKDEKGLKVLKWNFTTPRDEYIEQLKTQM 1200
GKKMPSKTSLKEDEDKSGPIFIVVPNGKEQRMKDEKGLKVLKWNFTTPRDEYIEQLKTQM
Sbjct: 1141 GKKMPSKTSLKEDEDKSGPIFIVVPNGKEQRMKDEKGLKVLKWNFTTPRDEYIEQLKTQM 1200
Query: 1201 SSCVAKWLQDEMFHSDFQHHNKALAVMVDHLESEKEGVIGCLDLILKWLTLRFFDTNTSV 1260
SSCVAKWLQDEMFHSDFQHHNKALAVMVDHLESEKEGVIGCLDLILKWLTLRFFDTNTSV
Sbjct: 1201 SSCVAKWLQDEMFHSDFQHHNKALAVMVDHLESEKEGVIGCLDLILKWLTLRFFDTNTSV 1260
Query: 1261 LMKALEYLKLLFTLLSEEEYHLTENEASSFIPYLVVKVGEPKDVIRKDVRAILNRMCLVY 1320
LMKALEYLKLLFTLLSEEEYHLTENEASSFIPYLVVKVGEPKDVIRKDVRAILNRMCLVY
Sbjct: 1261 LMKALEYLKLLFTLLSEEEYHLTENEASSFIPYLVVKVGEPKDVIRKDVRAILNRMCLVY 1320
Query: 1321 PASKMFPFIMEGTKSKNSKQRAECLEELGCLVESYGMNVCQPTPGKALKEIAVHIGDRDN 1380
PASKMFPFIMEGTKSKNSKQRAECLEELGCLVESYGMNVCQPTPGKALKEIAVHIGDRDN
Sbjct: 1321 PASKMFPFIMEGTKSKNSKQRAECLEELGCLVESYGMNVCQPTPGKALKEIAVHIGDRDN 1380
Query: 1381 AVRNAALNTIVTVYNVHGDQVFKLIGNLSEKDMSMLEERIKRSAKRPSAAPIKQVEEKPQ 1440
AVRNAALNTIVTVYNVHGDQVFKLIGNLSEKDMSMLEERIKRSAKRPSAAPIKQVEEKPQ
Sbjct: 1381 AVRNAALNTIVTVYNVHGDQVFKLIGNLSEKDMSMLEERIKRSAKRPSAAPIKQVEEKPQ 1440
Query: 1441 RAQNISSNANMLRKGPAEDMSSKLNQARSMSGHPEAAQMVRREFQLDLDEIENDNGTVRC 1500
RAQNISSNANMLRKGPAEDMSSKLNQARSMSGHPEAAQMVRREFQLDLDEIENDNGTVRC
Sbjct: 1441 RAQNISSNANMLRKGPAEDMSSKLNQARSMSGHPEAAQMVRREFQLDLDEIENDNGTVRC 1500
Query: 1501 EMPELVQHKLDDIFEPVLIPEPKIRAVSPHFDDMHSNTASTINFIISQVASGDINTSIQA 1560
EMPELVQHKLDDIFEPVLIPEPKIRAVSPHFDDMHSNTASTINFIISQVASGDINTSIQA
Sbjct: 1501 EMPELVQHKLDDIFEPVLIPEPKIRAVSPHFDDMHSNTASTINFIISQVASGDINTSIQA 1560
Query: 1561 LTQLFQIESLAREASTGVLKDLMHGLITLMLDSRIEDLEEGQQVIRSVNLLVVKVLEKSD 1620
LTQLFQIESLAREASTGVLKDLMHGLITLMLDSRIEDLEEGQQVIRSVNLLVVKVLEKSD
Sbjct: 1561 LTQLFQIESLAREASTGVLKDLMHGLITLMLDSRIEDLEEGQQVIRSVNLLVVKVLEKSD 1620
Query: 1621 QTNILSALLVLLQDSLLATASSPKFSELVMKCLWRMVRLLPDTINSINLDRILLDIHIFM 1680
QTNILSALLVLLQDSLLATASSPKFSELVMKCLWRMVRLLPDTINSINLDRILLDIHIFM
Sbjct: 1621 QTNILSALLVLLQDSLLATASSPKFSELVMKCLWRMVRLLPDTINSINLDRILLDIHIFM 1680
Query: 1681 KVFPKEKLKQCKSEFPIRTLKTLLHTLCKLKGPKILDHLTMIDNKNESELEAHLCRMMKH 1740
KVFPKEKLKQCKSEFPIRTLKTLLHTLCKLKGPKILDHLTMIDNKNESELEAHLCRMMKH
Sbjct: 1681 KVFPKEKLKQCKSEFPIRTLKTLLHTLCKLKGPKILDHLTMIDNKNESELEAHLCRMMKH 1740
Query: 1741 SMDQTGSKSDKETEKGASRIDEKSSKAKVNDFLAEIFKKIGSKENTKEGLAELYEYKKKY 1800
SMDQTGSKSDKETEKGASRIDEKSSKAKVNDFLAEIFKKIGSKENTKEGLAELYEYKKKY
Sbjct: 1741 SMDQTGSKSDKETEKGASRIDEKSSKAKVNDFLAEIFKKIGSKENTKEGLAELYEYKKKY 1800
Query: 1801 SDADIEPFLKNSSQFFQSYVERGLRVIEMEREGKGRISTSTGISPQMEVTCVPTPTSTVS 1860
SDADIEPFLKNSSQFFQSYVERGLRVIEMEREGKGRISTSTGISPQMEVTCVPTPTSTVS
Sbjct: 1801 SDADIEPFLKNSSQFFQSYVERGLRVIEMEREGKGRISTSTGISPQMEVTCVPTPTSTVS 1860
Query: 1861 SIGNTNGEEVGPSVYLERLKILRQRCGLDNTKQDDRPPLTSLLSKPAVPTVASSTDMLHS 1920
SIGNTNGEEVGPSVYLERLKILRQRCGLDNTKQDDRPPLTSLLSKPAVPTVASSTDMLHS
Sbjct: 1861 SIGNTNGEEVGPSVYLERLKILRQRCGLDNTKQDDRPPLTSLLSKPAVPTVASSTDMLHS 1920
Query: 1921 KLSQLRESREQHQHSDLDSNQTHSSGTVTSSSSTANIDDLKKRLERIKSSRK 1972
KLSQLRESREQHQHSDLDSNQTHSSGTVTSSSSTANIDDLKKRLERIKSSRK
Sbjct: 1921 KLSQLRESREQHQHSDLDSNQTHSSGTVTSSSSTANIDDLKKRLERIKSSRK 1972
>gi|57164942 colonic and hepatic tumor over-expressed protein isoform
a [Homo sapiens]
Length = 2032
Score = 3777 bits (9794), Expect = 0.0
Identities = 1944/2032 (95%), Positives = 1953/2032 (96%), Gaps = 60/2032 (2%)
Query: 1 MGDDSEWLKLPVDQKCEHKLWKARLSGYEEALKIFQKIKDEKSPEWSKFLGLIKKFVTDS 60
MGDDSEWLKLPVDQKCEHKLWKARLSGYEEALKIFQKIKDEKSPEWSKFLGLIKKFVTDS
Sbjct: 1 MGDDSEWLKLPVDQKCEHKLWKARLSGYEEALKIFQKIKDEKSPEWSKFLGLIKKFVTDS 60
Query: 61 NAVVQLKGLEAALVYVENAHVAGKTTGEVVSGVVSKVFNQPKAKAKELGIEICLMYIEIE 120
NAVVQLKGLEAALVYVENAHVAGKTTGEVVSGVVSKVFNQPKAKAKELGIEICLMYIEIE
Sbjct: 61 NAVVQLKGLEAALVYVENAHVAGKTTGEVVSGVVSKVFNQPKAKAKELGIEICLMYIEIE 120
Query: 121 KGEAVQEELLKGLDNKNPKIIVACIETLRKALSEFGSKIILLKPIIKVLPKLFESREKAV 180
KGEAVQEELLKGLDNKNPKIIVACIETLRKALSEFGSKIILLKPIIKVLPKLFESREKAV
Sbjct: 121 KGEAVQEELLKGLDNKNPKIIVACIETLRKALSEFGSKIILLKPIIKVLPKLFESREKAV 180
Query: 181 RDEAKLIAVEIYRWIRDALRPPLQNINSVQLKELEEEWVKLPTSAPRPTRFLRSQQELEA 240
RDEAKLIAVEIYRWIRDALRPPLQNINSVQLKELEEEWVKLPTSAPRPTRFLRSQQELEA
Sbjct: 181 RDEAKLIAVEIYRWIRDALRPPLQNINSVQLKELEEEWVKLPTSAPRPTRFLRSQQELEA 240
Query: 241 KLEQQQSAGGDAEGGGDDGDEVPQIDAYELLEAVEILSKLPKDFYDKIEAKKWQERKEAL 300
KLEQQQSAGGDAEGGGDDGDEVPQIDAYELLEAVEILSKLPKDFYDKIEAKKWQERKEAL
Sbjct: 241 KLEQQQSAGGDAEGGGDDGDEVPQIDAYELLEAVEILSKLPKDFYDKIEAKKWQERKEAL 300
Query: 301 ESVEVLIKNPKLEAGDYADLVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAG 360
ESVEVLIKNPKLEAGDYADLVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAG
Sbjct: 301 ESVEVLIKNPKLEAGDYADLVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAG 360
Query: 361 HVVPTILEKFKEKKPQVVQALQEAIDAIFLTTTLQNISEDVLAVMDNKNPTIKQQTSLFI 420
HVVPTILEKFKEKKPQVVQALQEAIDAIFLTTTLQNISEDVLAVMDNKNPTIKQQTSLFI
Sbjct: 361 HVVPTILEKFKEKKPQVVQALQEAIDAIFLTTTLQNISEDVLAVMDNKNPTIKQQTSLFI 420
Query: 421 ARSFRHCTASTLPKSLLKPFCAALLKHINDSAPEVRDAAFEALGTALKVVGEKAVNPFLA 480
ARSFRHCTASTLPKSLLKPFCAALLKHINDSAPEVRDAAFEALGTALKVVGEKAVNPFLA
Sbjct: 421 ARSFRHCTASTLPKSLLKPFCAALLKHINDSAPEVRDAAFEALGTALKVVGEKAVNPFLA 480
Query: 481 DVDKLKLDKIKECSEKVELIHGKKAGLAADKKEFKPLPGRTAASGAAGDKDTKDISAPKP 540
DVDKLKLDKIKECSEKVELIHGKKAGLAADKKEFKPLPGRTAASGAAGDKDTKDISAPKP
Sbjct: 481 DVDKLKLDKIKECSEKVELIHGKKAGLAADKKEFKPLPGRTAASGAAGDKDTKDISAPKP 540
Query: 541 GPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKGLETKEIVEPELSIEVCEEKASAVL 600
GPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKGLETKEIVEPELSIEVCEEKASAVL
Sbjct: 541 GPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKGLETKEIVEPELSIEVCEEKASAVL 600
Query: 601 PPTCIQLLDSSNWKERLACMEEFQKAVELMDRTEMPCQALVRMLAKKPGWKETNFQVMQM 660
PPTCIQLLDSSNWKERLACMEEFQKAVELMDRTEMPCQALVRMLAKKPGWKETNFQVMQM
Sbjct: 601 PPTCIQLLDSSNWKERLACMEEFQKAVELMDRTEMPCQALVRMLAKKPGWKETNFQVMQM 660
Query: 661 KLHIVALIAQKGNFSKTSAQVVLDGLVDKIGDVKCGNNAKEAMTAIAEACMLPWTAEQVV 720
KLHIVALIAQKGNFSKTSAQVVLDGLVDKIGDVKCGNNAKEAMTAIAEACMLPWTAEQVV
Sbjct: 661 KLHIVALIAQKGNFSKTSAQVVLDGLVDKIGDVKCGNNAKEAMTAIAEACMLPWTAEQVV 720
Query: 721 SMAFSQKNPKNQSETLNWLSNAIKEFGFSGLNVKAFISNVKTALAATNPAVRTAAITLLG 780
SMAFSQKNPKNQSETLNWLSNAIKEFGFSGLNVKAFISNVKTALAATNPAVRTAAITLLG
Sbjct: 721 SMAFSQKNPKNQSETLNWLSNAIKEFGFSGLNVKAFISNVKTALAATNPAVRTAAITLLG 780
Query: 781 VMYLYVGPSLRMFFEDEKPALLSQIDAEFEKMQGQSPPAPTRGISKHSTSGTDEGEDGDE 840
VMYLYVGPSLRMFFEDEKPALLSQIDAEFEKMQGQSPPAPTRGISKHSTSGTDEGEDGDE
Sbjct: 781 VMYLYVGPSLRMFFEDEKPALLSQIDAEFEKMQGQSPPAPTRGISKHSTSGTDEGEDGDE 840
Query: 841 PDDGSNDVVDLLPRTEISDKITSELVSKIGDKNWKIRKEGLDEVAGIINDAKFIQPNIGE 900
PDDGSNDVVDLLPRTEISDKITSELVSKIGDKNWKIRKEGLDEVAGIINDAKFIQPNIGE
Sbjct: 841 PDDGSNDVVDLLPRTEISDKITSELVSKIGDKNWKIRKEGLDEVAGIINDAKFIQPNIGE 900
Query: 901 LPTALKGRLNDSNKILVQQTLNILQQLAVAMGPNIKQHVKNLGIPIITVLGDSKNNVRAA 960
LPTALKGRLNDSNKILVQQTLNILQQLAVAMGPNIKQHVKNLGIPIITVLGDSKNNVRAA
Sbjct: 901 LPTALKGRLNDSNKILVQQTLNILQQLAVAMGPNIKQHVKNLGIPIITVLGDSKNNVRAA 960
Query: 961 ALATVNAWAEQTGMKEWLEGEDLSEELKKENPFLRQELLGWLAEKLPTLRSTPTDLILCV 1020
ALATVNAWAEQTGMKEWLEGEDLSEELKKENPFLRQELLGWLAEKLPTLRSTPTDLILCV
Sbjct: 961 ALATVNAWAEQTGMKEWLEGEDLSEELKKENPFLRQELLGWLAEKLPTLRSTPTDLILCV 1020
Query: 1021 PHLYSCLEDRNGDVRKKAQDALPFFMMHLGYEKMAKATGKLKPTSKDQVLAMLEKAKVNM 1080
PHLYSCLEDRNGDVRKKAQDALPFFMMHLGYEKMAKATGKLKPTSKDQVLAMLEKAKVNM
Sbjct: 1021 PHLYSCLEDRNGDVRKKAQDALPFFMMHLGYEKMAKATGKLKPTSKDQVLAMLEKAKVNM 1080
Query: 1081 PAKPAPPTKATSKPMGGSAPAKFQPASAPAEDCISSSTEPKPDPKKAKAPGLSSKAKSAQ 1140
PAKPAPPTKATSKPMGGSAPAKFQPASAPAEDCISSSTEPKPDPKKAKAPGLSSKAKSAQ
Sbjct: 1081 PAKPAPPTKATSKPMGGSAPAKFQPASAPAEDCISSSTEPKPDPKKAKAPGLSSKAKSAQ 1140
Query: 1141 GKKMPSKTSLKEDEDKSGPIFIVVPNGKEQRMKDEKGLKVLKWNFTTPRDEYIEQLKTQM 1200
GKKMPSKTSLKEDEDKSGPIFIVVPNGKEQRMKDEKGLKVLKWNFTTPRDEYIEQLKTQM
Sbjct: 1141 GKKMPSKTSLKEDEDKSGPIFIVVPNGKEQRMKDEKGLKVLKWNFTTPRDEYIEQLKTQM 1200
Query: 1201 SSCVAKWLQDEMFHSDFQHHNKALAVMVDHLESEKEGVIGCLDLILKWLTLRFFDTNTSV 1260
SSCVAKWLQDEMFHSDFQHHNKALAVMVDHLESEKEGVIGCLDLILKWLTLRFFDTNTSV
Sbjct: 1201 SSCVAKWLQDEMFHSDFQHHNKALAVMVDHLESEKEGVIGCLDLILKWLTLRFFDTNTSV 1260
Query: 1261 LMKALEYLKLLFTLLSEEEYHLTENEASSFIPYLVVKVGEPKDVIRKDVRAILNRMCLVY 1320
LMKALEYLKLLFTLLSEEEYHLTENEASSFIPYLVVKVGEPKDVIRKDVRAILNRMCLVY
Sbjct: 1261 LMKALEYLKLLFTLLSEEEYHLTENEASSFIPYLVVKVGEPKDVIRKDVRAILNRMCLVY 1320
Query: 1321 PASKMFPFIMEGTKSKNSKQRAECLEELGCLVESYGMNVCQPTPGKALKEIAVHIGDRDN 1380
PASKMFPFIMEGTKSKNSKQRAECLEELGCLVESYGMNVCQPTPGKALKEIAVHIGDRDN
Sbjct: 1321 PASKMFPFIMEGTKSKNSKQRAECLEELGCLVESYGMNVCQPTPGKALKEIAVHIGDRDN 1380
Query: 1381 AVRNAALNTIVTVYNVHGDQVFKLIGNLSEKDMSMLEERIKRSAKRPSAAPIKQVEEKPQ 1440
AVRNAALNTIVTVYNVHGDQVFKLIGNLSEKDMSMLEERIKRSAKRPSAAPIKQVEEKPQ
Sbjct: 1381 AVRNAALNTIVTVYNVHGDQVFKLIGNLSEKDMSMLEERIKRSAKRPSAAPIKQVEEKPQ 1440
Query: 1441 RAQNISSNANMLRKGPAEDMSSKLNQARSMSGHPEAAQMVRREFQLDLDEIENDNGTVRC 1500
RAQNISSNANMLRKGPAEDMSSKLNQARSMSGHPEAAQMVRREFQLDLDEIENDNGTVRC
Sbjct: 1441 RAQNISSNANMLRKGPAEDMSSKLNQARSMSGHPEAAQMVRREFQLDLDEIENDNGTVRC 1500
Query: 1501 EMPELVQHKLDDIFEPVLIPEPKIRAVSPHFDDMHSNTASTINFIISQVASGDINTSIQA 1560
EMPELVQHKLDDIFEPVLIPEPKIRAVSPHFDDMHSNTASTINFIISQVASGDINTSIQA
Sbjct: 1501 EMPELVQHKLDDIFEPVLIPEPKIRAVSPHFDDMHSNTASTINFIISQVASGDINTSIQA 1560
Query: 1561 LTQLFQI--ESLAREASTGVLKDLMHGLI--------TLMLDSRIE-------------- 1596
LTQ+ ++ + EA +G + + T M D ++E
Sbjct: 1561 LTQIDEVLRQEDKAEAMSGHIDQFLIATFMQLRLIYNTHMADEKLEKDEIIKLYSCIIGN 1620
Query: 1597 --------------------DLEEG----------------QQVIRSVNLLVVKVLEKSD 1620
DL G QQVIRSVNLLVVKVLEKSD
Sbjct: 1621 MISLFQIESLAREASTGVLKDLMHGLITLMLDSRIEDLEEGQQVIRSVNLLVVKVLEKSD 1680
Query: 1621 QTNILSALLVLLQDSLLATASSPKFSELVMKCLWRMVRLLPDTINSINLDRILLDIHIFM 1680
QTNILSALLVLLQDSLLATASSPKFSELVMKCLWRMVRLLPDTINSINLDRILLDIHIFM
Sbjct: 1681 QTNILSALLVLLQDSLLATASSPKFSELVMKCLWRMVRLLPDTINSINLDRILLDIHIFM 1740
Query: 1681 KVFPKEKLKQCKSEFPIRTLKTLLHTLCKLKGPKILDHLTMIDNKNESELEAHLCRMMKH 1740
KVFPKEKLKQCKSEFPIRTLKTLLHTLCKLKGPKILDHLTMIDNKNESELEAHLCRMMKH
Sbjct: 1741 KVFPKEKLKQCKSEFPIRTLKTLLHTLCKLKGPKILDHLTMIDNKNESELEAHLCRMMKH 1800
Query: 1741 SMDQTGSKSDKETEKGASRIDEKSSKAKVNDFLAEIFKKIGSKENTKEGLAELYEYKKKY 1800
SMDQTGSKSDKETEKGASRIDEKSSKAKVNDFLAEIFKKIGSKENTKEGLAELYEYKKKY
Sbjct: 1801 SMDQTGSKSDKETEKGASRIDEKSSKAKVNDFLAEIFKKIGSKENTKEGLAELYEYKKKY 1860
Query: 1801 SDADIEPFLKNSSQFFQSYVERGLRVIEMEREGKGRISTSTGISPQMEVTCVPTPTSTVS 1860
SDADIEPFLKNSSQFFQSYVERGLRVIEMEREGKGRISTSTGISPQMEVTCVPTPTSTVS
Sbjct: 1861 SDADIEPFLKNSSQFFQSYVERGLRVIEMEREGKGRISTSTGISPQMEVTCVPTPTSTVS 1920
Query: 1861 SIGNTNGEEVGPSVYLERLKILRQRCGLDNTKQDDRPPLTSLLSKPAVPTVASSTDMLHS 1920
SIGNTNGEEVGPSVYLERLKILRQRCGLDNTKQDDRPPLTSLLSKPAVPTVASSTDMLHS
Sbjct: 1921 SIGNTNGEEVGPSVYLERLKILRQRCGLDNTKQDDRPPLTSLLSKPAVPTVASSTDMLHS 1980
Query: 1921 KLSQLRESREQHQHSDLDSNQTHSSGTVTSSSSTANIDDLKKRLERIKSSRK 1972
KLSQLRESREQHQHSDLDSNQTHSSGTVTSSSSTANIDDLKKRLERIKSSRK
Sbjct: 1981 KLSQLRESREQHQHSDLDSNQTHSSGTVTSSSSTANIDDLKKRLERIKSSRK 2032
>gi|57863301 CLIP-associating protein 2 [Homo sapiens]
Length = 1506
Score = 57.8 bits (138), Expect = 1e-07
Identities = 57/253 (22%), Positives = 110/253 (43%), Gaps = 10/253 (3%)
Query: 649 GWK-ETNFQVMQMKLHIV-ALIAQKGNFSKTSAQVVLDGLVDKIGDVK--CGNNAKEAMT 704
GW +N++V M L I+ A + + K+ +V+ L+D++GD K + A+ +
Sbjct: 57 GWVGSSNYRVSLMGLEILSAFVDRLSTRFKSYVAMVIVALIDRMGDAKDKVRDEAQTLIL 116
Query: 705 AIAEACMLPWTAEQVVSMAFSQKNPKNQSETLNWLSNAIKEFGFSGLNVKAFISNVKTAL 764
+ + P + ++ F KN +++ L + FG L + I ++
Sbjct: 117 KLMDQVAPPMYIWEQLASGFKHKNFRSREGVCLCLIETLNIFGAQPLVISKLIPHLCILF 176
Query: 765 AATNPAVRTAAITLLGVMYLYVGPSLRM--FFEDEKPALLSQIDAEFEKMQGQSPPAPTR 822
+N VR AAI + +Y +VG +RM + PA L I A+F+++ QS
Sbjct: 177 GDSNSQVRDAAILAIVEIYRHVGEKVRMDLYKRGIPPARLEMIFAKFDEV--QSSGGMIL 234
Query: 823 GISKHSTSGTDEGEDGDEPDDGSNDVVDLLPRTEISDKITSELVSKIGDKNWKIRKEGLD 882
+ K + +E DG+ P ++ P+T + ++ G K+ +
Sbjct: 235 SVCKDKSFDDEESVDGNRPSSAASAFKVPAPKTSGNPANSARKPGSAGGP--KVGGASKE 292
Query: 883 EVAGIINDAKFIQ 895
AG +++ FI+
Sbjct: 293 GGAGAVDEDDFIK 305
Score = 55.8 bits (133), Expect = 4e-07
Identities = 86/372 (23%), Positives = 143/372 (38%), Gaps = 59/372 (15%)
Query: 48 KFLGLIKKFVTDSNAVVQLKGLEAALVYVENAHVAGKTTGEVVSGVVSKVFNQPKAKAKE 107
K + + +V SN V L GLE +V+ K+ +V + K K ++
Sbjct: 50 KTVDALTGWVGSSNYRVSLMGLEILSAFVDRLSTRFKSYVAMVIVALIDRMGDAKDKVRD 109
Query: 108 LGIEICLMYIE-IEKGEAVQEELLKGLDNKNPKIIVACIETLRKALSEFGSKIILLKPII 166
+ L ++ + + E+L G +KN + L + L+ FG++ +++ +I
Sbjct: 110 EAQTLILKLMDQVAPPMYIWEQLASGFKHKNFRSREGVCLCLIETLNIFGAQPLVISKLI 169
Query: 167 KVLPKLFESREKAVRDEAKLIAVEIYRWIRDALRPPL--QNINSVQLKEL---------- 214
L LF VRD A L VEIYR + + +R L + I +L+ +
Sbjct: 170 PHLCILFGDSNSQVRDAAILAIVEIYRHVGEKVRMDLYKRGIPPARLEMIFAKFDEVQSS 229
Query: 215 --------------EEEWV--KLPTSA------PRPTRFLRSQQELEAKLEQQQSAGGDA 252
+EE V P+SA P P ++ + SAGG
Sbjct: 230 GGMILSVCKDKSFDDEESVDGNRPSSAASAFKVPAP----KTSGNPANSARKPGSAGGPK 285
Query: 253 EGGG---------DDGD------EVPQIDAYELLEAVEILSKLPKDFYDKIEAKKWQERK 297
GG D+ D +VP I Y E E L+K+ + D + W +R
Sbjct: 286 VGGASKEGGAGAVDEDDFIKAFTDVPSIQIYSSRELEETLNKIREILSD--DKHDWDQRA 343
Query: 298 EALESVEVLIKNPKLEAG---DYADLVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKK 354
AL+ + L+ + + L+ K+ KD +V A + L+ L K
Sbjct: 344 NALKKIRSLLVAGAAQYDCFFQHLRLLDGALKLSAKDLRSQVVREACITVAHLSTVLGNK 403
Query: 355 FGQYAGHVVPTI 366
F A +VPT+
Sbjct: 404 FDHGAEAIVPTL 415
Score = 55.1 bits (131), Expect = 7e-07
Identities = 128/609 (21%), Positives = 222/609 (36%), Gaps = 70/609 (11%)
Query: 886 GIINDAKFIQPNIGELPTALKGRLNDSNKILVQQTLNILQQLAVAMGPNIKQHVKNLGIP 945
G I+D + +G+ AL G + SN + L IL + K +V + +
Sbjct: 36 GAISDLEEDLGRLGKTVDALTGWVGSSNYRVSLMGLEILSAFVDRLSTRFKSYVAMVIVA 95
Query: 946 IITVLGDSKNNVRAAALATVNAWAEQTGMKEWLEGEDLSEELKKENPFLRQELLGWLAEK 1005
+I +GD+K+ VR A + +Q ++ E L+ K +N R+ + L E
Sbjct: 96 LIDRMGDAKDKVRDEAQTLILKLMDQVAPPMYI-WEQLASGFKHKNFRSREGVCLCLIET 154
Query: 1006 LPTLRSTPTDLILCVPHLYSCLEDRNGDVRKKAQDALPFFMMHLGYE-KMAKATGKLKPT 1064
L + P + +PHL D N VR A A+ H+G + +M + P
Sbjct: 155 LNIFGAQPLVISKLIPHLCILFGDSNSQVRDAAILAIVEIYRHVGEKVRMDLYKRGIPPA 214
Query: 1065 SKDQVLAMLEKAKVNMPAKPAPPTKATSKPMGGSAPAKFQPASAPAEDCI-------SSS 1117
+ + A ++ + + GG + + S E+ + ++S
Sbjct: 215 RLEMIFAKFDEVQSS----------------GGMILSVCKDKSFDDEESVDGNRPSSAAS 258
Query: 1118 TEPKPDPKKAKAPGLSS-KAKSAQGKKMPSKTSLKE------DEDKSGPIFIVVPNGKEQ 1170
P PK + P S+ K SA G K+ + KE DED F VP+ +
Sbjct: 259 AFKVPAPKTSGNPANSARKPGSAGGPKVGGAS--KEGGAGAVDEDDFIKAFTDVPSIQIY 316
Query: 1171 RMKD-EKGLKVLKWNFTTPR---DEYIEQLKTQMSSCVAKWLQDEMFHSDFQHHNKALAV 1226
++ E+ L ++ + + D+ LK S VA Q + F FQH
Sbjct: 317 SSRELEETLNKIREILSDDKHDWDQRANALKKIRSLLVAGAAQYDCF---FQH------- 366
Query: 1227 MVDHLESEKEGVIGCLDLILKWLTLRFFDTNTSVLMKALEYLKLLFTLLSEEEYHLTENE 1286
L L+ L L D + V+ +A + L T+L + H
Sbjct: 367 ---------------LRLLDGALKLSAKDLRSQVVREACITVAHLSTVLGNKFDH----G 407
Query: 1287 ASSFIPYLVVKVGEPKDVIRKDVRAILNRMCLVYPASKMFPFIMEGTKSKNSKQRAECLE 1346
A + +P L V V+ A + + ++ P I SK+ R E
Sbjct: 408 AEAIVPTLFNLVPNSAKVMATSGCAAIRFIIRHTHVPRLIPLITSNCTSKSVPVRRRSFE 467
Query: 1347 ELGCLVESYGMNVCQPTPGKALKEIAVHIGDRDNAVRNAALNTIVTVYNVHGDQVFKLIG 1406
L L++ + + + ++ I I D D R A T + + N + L
Sbjct: 468 FLDLLLQEWQTHSLERHAAVLVETIKKGIHDADAEARVEARKTYMGLRNHFPGEAETLYN 527
Query: 1407 NLSEKDMSMLEERIKRSAKRPSAAPIKQVEEKPQRAQNISSNANMLRKGP---AEDMSSK 1463
+L L+ +K S S + Q + N ++ P A +S+
Sbjct: 528 SLEPSYQKSLQTYLKSSGSVASLPQSDRSSSSSQESLNRPFSSKWSTANPSTVAGRVSAG 587
Query: 1464 LNQARSMSG 1472
++A S+ G
Sbjct: 588 SSKASSLPG 596
Score = 47.8 bits (112), Expect = 1e-04
Identities = 62/261 (23%), Positives = 105/261 (40%), Gaps = 14/261 (5%)
Query: 313 EAGDYADLVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAGHVVPTILEKFKE 372
+ G V AL VG +N + + + L+ L +F Y V+ ++++ +
Sbjct: 44 DLGRLGKTVDALTGWVGS-SNYRVSLMGLEILSAFVDRLSTRFKSYVAMVIVALIDRMGD 102
Query: 373 KKPQVVQALQEAIDAIF-LTTTLQNISEDVLAVMDNKNPTIKQQTSLFIARSFRHCTAST 431
K +V Q I + I E + + +KN ++ L + + A
Sbjct: 103 AKDKVRDEAQTLILKLMDQVAPPMYIWEQLASGFKHKNFRSREGVCLCLIETLNIFGAQP 162
Query: 432 LPKSLLKPFCAALLKHINDSAPEVRDAAFEALGTALKVVGEKA-VNPFLADVDKLKLDKI 490
L S L P L DS +VRDAA A+ + VGEK ++ + + +L+ I
Sbjct: 163 LVISKLIPHLCILF---GDSNSQVRDAAILAIVEIYRHVGEKVRMDLYKRGIPPARLEMI 219
Query: 491 KECSEKVELIHGKKAGLAADKK--EFKPLPGRTAASGAAGDKDTKDISAPKP--GPLKKA 546
++V+ G + DK + + + G +S A+ K + APK P A
Sbjct: 220 FAKFDEVQSSGGMILSVCKDKSFDDEESVDGNRPSSAASAFK----VPAPKTSGNPANSA 275
Query: 547 PAAKAGGPPKKGKPAAPGGAG 567
+ G PK G + GGAG
Sbjct: 276 RKPGSAGGPKVGGASKEGGAG 296
Score = 39.3 bits (90), Expect = 0.038
Identities = 52/235 (22%), Positives = 97/235 (41%), Gaps = 12/235 (5%)
Query: 257 DDGDEVPQIDAYELLEAVEILSKLPKDFYDKIEAKKWQERKEALESVEVLIKNPKLEAGD 316
DD D+ P + + + V L K + +++E ERK AL + L + D
Sbjct: 1255 DDADQFPDDLSLDHSDLVAELLKELSNHNERVE-----ERKIALYELMKLTQEESFSVWD 1309
Query: 317 --YADLVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAGHVVPTILEKFKEKK 374
+ ++ L + +G D + ALA K L + +F YA V LE K+
Sbjct: 1310 EHFKTILLLLLETLG-DKEPTIRALALKVLREILRHQPARFKNYAELTVMKTLEAHKDPH 1368
Query: 375 PQVVQALQEAIDAIFLTTTLQNISEDVLAVMDNKNPTIKQQTSLFIARSFRHCTASTLPK 434
+VV++ +EA + + + + + + ++ + I + + TL
Sbjct: 1369 KEVVRSAEEAASVLATSISPEQCIKVLCPIIQTADYPINLAAIKMQTKVIERVSKETL-N 1427
Query: 435 SLLKPFCAALLKHINDSAPEVRDAAFEALGTALKVVGEKAVNPFLADV--DKLKL 487
LL L++ ++S VR A L V+G++ + P L+ + K+KL
Sbjct: 1428 LLLPEIMPGLIQGYDNSESSVRKACVFCLVAVHAVIGDE-LKPHLSQLTGSKMKL 1481
>gi|214010175 CLIP-associating protein 1 isoform 3 [Homo sapiens]
Length = 1471
Score = 54.3 bits (129), Expect = 1e-06
Identities = 99/541 (18%), Positives = 197/541 (36%), Gaps = 58/541 (10%)
Query: 51 GLIKKFVTDSNAVVQLKGLEAALVYVENAHVAGKTT-GEVVSGVVSKVFNQPKAKAKELG 109
GL +V SN V L G++ V K G V+ ++ ++ + + ++
Sbjct: 53 GLATSWVNSSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQ 112
Query: 110 IEICLMYIEIEKGEAVQEELLKGLDNKNPKIIVACIETLRKALSEFGSKIILLKPIIKVL 169
+ + + + V + +L G +KN + L L+ G++ + L I+ +
Sbjct: 113 TLLLKIMDQAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHI 172
Query: 170 PKLFESREKAVRDEAKLIAVEIYRWIRDALRPPLQN------------------------ 205
L VRD A VEIYR + + +R L
Sbjct: 173 CNLLGDPNSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNM 232
Query: 206 INSVQLKELEEE--------------WVKLPTSAPRPTRFLRSQQELEAKLEQQQSAGGD 251
I S K ++E K P S+ R +++ + L + SA +
Sbjct: 233 IQSANDKNFDDEDSVDGNRPSSASSTSSKAPPSSRRNVGMGTTRRLGSSTLGSKSSAAKE 292
Query: 252 AEGGGDDGD------EVPQIDAYELLEAVEILSKLPKDFYDKIEAKKWQERKEALESVEV 305
G D+ D +VP + Y + E ++K+ + D + W++R AL+ +
Sbjct: 293 GAGAVDEEDFIKAFDDVPVVQIYSSRDLEESINKIREILSD--DKHDWEQRVNALKKIRS 350
Query: 306 LIKNPKLEAGDYADLVKALK---KVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAGHV 362
L+ E ++ ++ L K+ KD +V A L L+ L KF A +
Sbjct: 351 LLLAGAAEYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAI 410
Query: 363 VPTILEKFKEKKPQVVQALQEAIDAIFLTTTLQNISEDVLAVMDNKNPTIKQQTSLFIAR 422
+PTI + + A+ I T + + + + +K+ ++++ F+
Sbjct: 411 MPTIFNLIPNSAKIMATSGVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDL 470
Query: 423 SFRHCTASTLPKSLLKPFCAALLKHINDSAPEVRDAA---FEALGTALKVVGEKAVNPFL 479
+ +L + + + K I+D+ E R A + + E +
Sbjct: 471 LLQEWQTHSLERH-ISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLE 529
Query: 480 ADVDKLKLDKIKECSEKVELIHGKKAGLAADKKEFKPLPGRTAASGA----AGDKDTKDI 535
+ K +K V L ++ ++ + +PL + + +G+ A TK +
Sbjct: 530 SSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSV 589
Query: 536 S 536
S
Sbjct: 590 S 590
Score = 50.4 bits (119), Expect = 2e-05
Identities = 48/208 (23%), Positives = 94/208 (45%), Gaps = 28/208 (13%)
Query: 1197 KTQMSSCVAKWLQDEMFHSDFQHHNKALAVMVDHLESEKEGVIGCLDLILKWLTLRFFDT 1256
+ Q+ + + D+ +D +H L +VD L + W+ +
Sbjct: 20 RLQVGQELIDYFSDKQKSADLEHDQTMLDKLVDGLATS-------------WVN----SS 62
Query: 1257 NTSVLMKALEYLKLLFTLLSEEEYHLTENEASSFIPYLVVKVGEPKDVIRK-DVRAILNR 1315
N V++ ++ L L T L + + + + +P L+ ++G+ KD +R+ D +L
Sbjct: 63 NYKVVLLGMDILSALVTRLQDR----FKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKI 118
Query: 1316 MCLVYPASKMFPFIMEGTKSKNSKQRAE-CLEELGCLVESYGMNVCQP-TPGKALKEIAV 1373
M ++ ++ G K KN + R CL CL+ + + Q T K + I
Sbjct: 119 MDQAANPQYVWDRMLGGFKHKNFRTREGICL----CLIATLNASGAQTLTLSKIVPHICN 174
Query: 1374 HIGDRDNAVRNAALNTIVTVYNVHGDQV 1401
+GD ++ VR+AA+N++V +Y G++V
Sbjct: 175 LLGDPNSQVRDAAINSLVEIYRHVGERV 202
Score = 43.1 bits (100), Expect = 0.003
Identities = 48/246 (19%), Positives = 94/246 (38%), Gaps = 6/246 (2%)
Query: 653 TNFQVMQMKLHIV-ALIAQKGNFSKTSAQVVLDGLVDKIGDVKCGNNAKEA--MTAIAEA 709
+N++V+ + + I+ AL+ + + K VL L+D++GD K ++ + I +
Sbjct: 62 SNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKIMDQ 121
Query: 710 CMLPWTAEQVVSMAFSQKNPKNQSETLNWLSNAIKEFGFSGLNVKAFISNVKTALAATNP 769
P + F KN + + L + G L + + ++ L N
Sbjct: 122 AANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLGDPNS 181
Query: 770 AVRTAAITLLGVMYLYVGPSLRMFFEDEKPALLSQIDAEFEKMQGQSPPAPTRGISKHST 829
VR AAI L +Y +VG +R +K S+++ F K +
Sbjct: 182 QVRDAAINSLVEIYRHVGERVRADL-SKKGLPQSRLNVIFTKFDEVQKSGNMIQSANDKN 240
Query: 830 SGTDEGEDGDEPDDGSNDVVDLLPRTEISDKITSELVSKIGDKNWKIRKEGLDEVAGIIN 889
++ DG+ P S+ P + + ++G + E AG ++
Sbjct: 241 FDDEDSVDGNRPSSASSTSSKAPPSSR--RNVGMGTTRRLGSSTLGSKSSAAKEGAGAVD 298
Query: 890 DAKFIQ 895
+ FI+
Sbjct: 299 EEDFIK 304
Score = 42.7 bits (99), Expect = 0.003
Identities = 63/284 (22%), Positives = 111/284 (39%), Gaps = 34/284 (11%)
Query: 320 LVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAGHVVPTILEKFKEKKPQVVQ 379
LV L +N +V L L+ L L+ +F G V+P+++++ + K V +
Sbjct: 50 LVDGLATSWVNSSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVRE 109
Query: 380 ALQEAIDAIF-LTTTLQNISEDVLAVMDNKNPTIKQQTSLFIARSFRHCTASTLPKSLLK 438
Q + I Q + + +L +KN ++ L + + A TL S +
Sbjct: 110 QDQTLLLKIMDQAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIV 169
Query: 439 PFCAALLKHINDSAPEVRDAAFEALGTALKVVGEKAVNPFLADVDKLKLDKIKECSEKVE 498
P LL D +VRDAA +L + VGE+ AD+ K L + + +
Sbjct: 170 PHICNLL---GDPNSQVRDAAINSLVEIYRHVGERV----RADLSKKGLPQSRLNVIFTK 222
Query: 499 LIHGKKAG---LAADKKEFKPLPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPP 555
+K+G +A+ K F D+D+ D + P A + + PP
Sbjct: 223 FDEVQKSGNMIQSANDKNF-------------DDEDSVDGNRP-----SSASSTSSKAPP 264
Query: 556 KKGKPAAPG-----GAGNTGTKNKKGLETKEIVEPELSIEVCEE 594
+ G G+ G+K+ E V+ E I+ ++
Sbjct: 265 SSRRNVGMGTTRRLGSSTLGSKSSAAKEGAGAVDEEDFIKAFDD 308
Score = 42.0 bits (97), Expect = 0.006
Identities = 105/566 (18%), Positives = 196/566 (34%), Gaps = 39/566 (6%)
Query: 909 LNDSNKILVQQTLNILQQLAVAMGPNIKQHVKNLGIPIITVLGDSKNNVRAAALATVNAW 968
+N SN +V ++IL L + K + + +I LGD+K++VR +
Sbjct: 59 VNSSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKI 118
Query: 969 AEQTGMKEWLEGEDLSEELKKENPFLRQELLGWLAEKLPTLRSTPTDLILCVPHLYSCLE 1028
+Q +++ L K +N R+ + L L + L VPH+ + L
Sbjct: 119 MDQAANPQYVWDRMLGG-FKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLG 177
Query: 1029 DRNGDVRKKAQDALPFFMMHLGYEKMAKATGKLKPTSKDQVLAMLEKAKVNMPAKPAPPT 1088
D N VR A ++L H+G A + K P S+ V+ T
Sbjct: 178 DPNSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIF----------------T 221
Query: 1089 KATSKPMGGSAPAKFQPASAPAEDCISSSTEPKPDPKKAKAPGLSSKAKSAQG--KKMPS 1146
K G+ + ED + + +KAP SS+ G +++ S
Sbjct: 222 KFDEVQKSGNMIQSANDKNFDDEDSVDGNRPSSASSTSSKAPP-SSRRNVGMGTTRRLGS 280
Query: 1147 KT-SLKEDEDKSGPIFIVVPNGKEQRMKDEKGLKVLKWNFTTPRDEYIEQLKTQMSSCVA 1205
T K K G + +E +K + V++ + +E I +++ +S
Sbjct: 281 STLGSKSSAAKEGAGAV----DEEDFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKH 336
Query: 1206 KWLQDEMFHSDFQHHNKALAVMVDHLESEKEGVIGCLDLILKWLTLRFFDTNTSVLMKAL 1265
W Q + A A D+ + G L K D + V+ +A
Sbjct: 337 DWEQRVNALKKIRSLLLAGAAEYDNFFQHLRLLDGAFKLSAK-------DLRSQVVREAC 389
Query: 1266 EYLKLLFTLLSEEEYHLTENEASSFIPYLVVKVGEPKDVIRKDVRAILNRMCLVYPASKM 1325
L L ++L + H A + +P + + ++ + + ++
Sbjct: 390 ITLGHLSSVLGNKFDH----GAEAIMPTIFNLIPNSAKIMATSGVVAVRLIIRHTHIPRL 445
Query: 1326 FPFIMEGTKSKNSKQRAECLEELGCLVESYGMNVCQPTPGKALKEIAVHIGDRDNAVRNA 1385
P I SK+ R C E L L++ + + + + I I D D+ R
Sbjct: 446 IPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSLERHISVLAETIKKGIHDADSEARIE 505
Query: 1386 ALNTIVTVYNVHGDQVFKLIGNLSEKDMSMLEERIKRSAKRPSAAPIKQVEEKPQRAQNI 1445
A ++ + L L L+ +K S S + Q + +Q
Sbjct: 506 ARKCYWGFHSHFSREAEHLYHTLESSYQKALQSHLKNS---DSIVSLPQSDRSSSSSQES 562
Query: 1446 SSNANMLRKGPAEDMSSKLNQARSMS 1471
+ ++ P +S+ + + S
Sbjct: 563 LNRPLSAKRSPTGSTTSRASTVSTKS 588
Score = 33.5 bits (75), Expect = 2.1
Identities = 54/246 (21%), Positives = 98/246 (39%), Gaps = 21/246 (8%)
Query: 260 DEVPQIDAYELLEAV-----EILSKLPKDFYDKI---------EAKKWQERKEALESVEV 305
D + D L EAV E L +P D D + ++ +ERK AL +
Sbjct: 1204 DAINTYDKTALKEAVFDDDMEQLRDVPIDHSDLVADLLKELSNHNERVEERKGALLELLK 1263
Query: 306 LIKNPKLEAGD--YADLVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAGHVV 363
+ + L + + ++ L + +G D + + ALA + L + +F YA +
Sbjct: 1264 ITREDSLGVWEEHFKTILLLLLETLG-DKDHSIRALALRVLREILRNQPARFKNYAELTI 1322
Query: 364 PTILEKFKEKKPQVVQALQEAIDAIFLTTTLQNISEDVLAVMDNKNPTIKQQTSLFIARS 423
LE K+ +VV+A +EA + + + + + ++ + I +
Sbjct: 1323 MKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIIQTADYPINLAAIKMQTKV 1382
Query: 424 FRHCTASTLPKSLLKPFCAALLKHINDSAPEVRDAAFEALGTALKVVGEKAVNPFLADV- 482
+L LL LL+ +++ VR A+ L V+GE + P LA +
Sbjct: 1383 VERIAKESL-LQLLVDIIPGLLQGYDNTESSVRKASVFCLVAIYSVIGED-LKPHLAQLT 1440
Query: 483 -DKLKL 487
K+KL
Sbjct: 1441 GSKMKL 1446
>gi|214010173 CLIP-associating protein 1 isoform 2 [Homo sapiens]
Length = 1479
Score = 54.3 bits (129), Expect = 1e-06
Identities = 99/541 (18%), Positives = 197/541 (36%), Gaps = 58/541 (10%)
Query: 51 GLIKKFVTDSNAVVQLKGLEAALVYVENAHVAGKTT-GEVVSGVVSKVFNQPKAKAKELG 109
GL +V SN V L G++ V K G V+ ++ ++ + + ++
Sbjct: 53 GLATSWVNSSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQ 112
Query: 110 IEICLMYIEIEKGEAVQEELLKGLDNKNPKIIVACIETLRKALSEFGSKIILLKPIIKVL 169
+ + + + V + +L G +KN + L L+ G++ + L I+ +
Sbjct: 113 TLLLKIMDQAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHI 172
Query: 170 PKLFESREKAVRDEAKLIAVEIYRWIRDALRPPLQN------------------------ 205
L VRD A VEIYR + + +R L
Sbjct: 173 CNLLGDPNSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNM 232
Query: 206 INSVQLKELEEE--------------WVKLPTSAPRPTRFLRSQQELEAKLEQQQSAGGD 251
I S K ++E K P S+ R +++ + L + SA +
Sbjct: 233 IQSANDKNFDDEDSVDGNRPSSASSTSSKAPPSSRRNVGMGTTRRLGSSTLGSKSSAAKE 292
Query: 252 AEGGGDDGD------EVPQIDAYELLEAVEILSKLPKDFYDKIEAKKWQERKEALESVEV 305
G D+ D +VP + Y + E ++K+ + D + W++R AL+ +
Sbjct: 293 GAGAVDEEDFIKAFDDVPVVQIYSSRDLEESINKIREILSD--DKHDWEQRVNALKKIRS 350
Query: 306 LIKNPKLEAGDYADLVKALK---KVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAGHV 362
L+ E ++ ++ L K+ KD +V A L L+ L KF A +
Sbjct: 351 LLLAGAAEYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAI 410
Query: 363 VPTILEKFKEKKPQVVQALQEAIDAIFLTTTLQNISEDVLAVMDNKNPTIKQQTSLFIAR 422
+PTI + + A+ I T + + + + +K+ ++++ F+
Sbjct: 411 MPTIFNLIPNSAKIMATSGVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDL 470
Query: 423 SFRHCTASTLPKSLLKPFCAALLKHINDSAPEVRDAA---FEALGTALKVVGEKAVNPFL 479
+ +L + + + K I+D+ E R A + + E +
Sbjct: 471 LLQEWQTHSLERH-ISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLE 529
Query: 480 ADVDKLKLDKIKECSEKVELIHGKKAGLAADKKEFKPLPGRTAASGA----AGDKDTKDI 535
+ K +K V L ++ ++ + +PL + + +G+ A TK +
Sbjct: 530 SSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSV 589
Query: 536 S 536
S
Sbjct: 590 S 590
Score = 50.4 bits (119), Expect = 2e-05
Identities = 48/208 (23%), Positives = 94/208 (45%), Gaps = 28/208 (13%)
Query: 1197 KTQMSSCVAKWLQDEMFHSDFQHHNKALAVMVDHLESEKEGVIGCLDLILKWLTLRFFDT 1256
+ Q+ + + D+ +D +H L +VD L + W+ +
Sbjct: 20 RLQVGQELIDYFSDKQKSADLEHDQTMLDKLVDGLATS-------------WVN----SS 62
Query: 1257 NTSVLMKALEYLKLLFTLLSEEEYHLTENEASSFIPYLVVKVGEPKDVIRK-DVRAILNR 1315
N V++ ++ L L T L + + + + +P L+ ++G+ KD +R+ D +L
Sbjct: 63 NYKVVLLGMDILSALVTRLQDR----FKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKI 118
Query: 1316 MCLVYPASKMFPFIMEGTKSKNSKQRAE-CLEELGCLVESYGMNVCQP-TPGKALKEIAV 1373
M ++ ++ G K KN + R CL CL+ + + Q T K + I
Sbjct: 119 MDQAANPQYVWDRMLGGFKHKNFRTREGICL----CLIATLNASGAQTLTLSKIVPHICN 174
Query: 1374 HIGDRDNAVRNAALNTIVTVYNVHGDQV 1401
+GD ++ VR+AA+N++V +Y G++V
Sbjct: 175 LLGDPNSQVRDAAINSLVEIYRHVGERV 202
Score = 43.1 bits (100), Expect = 0.003
Identities = 48/246 (19%), Positives = 94/246 (38%), Gaps = 6/246 (2%)
Query: 653 TNFQVMQMKLHIV-ALIAQKGNFSKTSAQVVLDGLVDKIGDVKCGNNAKEA--MTAIAEA 709
+N++V+ + + I+ AL+ + + K VL L+D++GD K ++ + I +
Sbjct: 62 SNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKIMDQ 121
Query: 710 CMLPWTAEQVVSMAFSQKNPKNQSETLNWLSNAIKEFGFSGLNVKAFISNVKTALAATNP 769
P + F KN + + L + G L + + ++ L N
Sbjct: 122 AANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLGDPNS 181
Query: 770 AVRTAAITLLGVMYLYVGPSLRMFFEDEKPALLSQIDAEFEKMQGQSPPAPTRGISKHST 829
VR AAI L +Y +VG +R +K S+++ F K +
Sbjct: 182 QVRDAAINSLVEIYRHVGERVRADL-SKKGLPQSRLNVIFTKFDEVQKSGNMIQSANDKN 240
Query: 830 SGTDEGEDGDEPDDGSNDVVDLLPRTEISDKITSELVSKIGDKNWKIRKEGLDEVAGIIN 889
++ DG+ P S+ P + + ++G + E AG ++
Sbjct: 241 FDDEDSVDGNRPSSASSTSSKAPPSSR--RNVGMGTTRRLGSSTLGSKSSAAKEGAGAVD 298
Query: 890 DAKFIQ 895
+ FI+
Sbjct: 299 EEDFIK 304
Score = 42.7 bits (99), Expect = 0.003
Identities = 63/284 (22%), Positives = 111/284 (39%), Gaps = 34/284 (11%)
Query: 320 LVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAGHVVPTILEKFKEKKPQVVQ 379
LV L +N +V L L+ L L+ +F G V+P+++++ + K V +
Sbjct: 50 LVDGLATSWVNSSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVRE 109
Query: 380 ALQEAIDAIF-LTTTLQNISEDVLAVMDNKNPTIKQQTSLFIARSFRHCTASTLPKSLLK 438
Q + I Q + + +L +KN ++ L + + A TL S +
Sbjct: 110 QDQTLLLKIMDQAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIV 169
Query: 439 PFCAALLKHINDSAPEVRDAAFEALGTALKVVGEKAVNPFLADVDKLKLDKIKECSEKVE 498
P LL D +VRDAA +L + VGE+ AD+ K L + + +
Sbjct: 170 PHICNLL---GDPNSQVRDAAINSLVEIYRHVGERV----RADLSKKGLPQSRLNVIFTK 222
Query: 499 LIHGKKAG---LAADKKEFKPLPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPP 555
+K+G +A+ K F D+D+ D + P A + + PP
Sbjct: 223 FDEVQKSGNMIQSANDKNF-------------DDEDSVDGNRP-----SSASSTSSKAPP 264
Query: 556 KKGKPAAPG-----GAGNTGTKNKKGLETKEIVEPELSIEVCEE 594
+ G G+ G+K+ E V+ E I+ ++
Sbjct: 265 SSRRNVGMGTTRRLGSSTLGSKSSAAKEGAGAVDEEDFIKAFDD 308
Score = 42.0 bits (97), Expect = 0.006
Identities = 105/566 (18%), Positives = 196/566 (34%), Gaps = 39/566 (6%)
Query: 909 LNDSNKILVQQTLNILQQLAVAMGPNIKQHVKNLGIPIITVLGDSKNNVRAAALATVNAW 968
+N SN +V ++IL L + K + + +I LGD+K++VR +
Sbjct: 59 VNSSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKI 118
Query: 969 AEQTGMKEWLEGEDLSEELKKENPFLRQELLGWLAEKLPTLRSTPTDLILCVPHLYSCLE 1028
+Q +++ L K +N R+ + L L + L VPH+ + L
Sbjct: 119 MDQAANPQYVWDRMLGG-FKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLG 177
Query: 1029 DRNGDVRKKAQDALPFFMMHLGYEKMAKATGKLKPTSKDQVLAMLEKAKVNMPAKPAPPT 1088
D N VR A ++L H+G A + K P S+ V+ T
Sbjct: 178 DPNSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIF----------------T 221
Query: 1089 KATSKPMGGSAPAKFQPASAPAEDCISSSTEPKPDPKKAKAPGLSSKAKSAQG--KKMPS 1146
K G+ + ED + + +KAP SS+ G +++ S
Sbjct: 222 KFDEVQKSGNMIQSANDKNFDDEDSVDGNRPSSASSTSSKAPP-SSRRNVGMGTTRRLGS 280
Query: 1147 KT-SLKEDEDKSGPIFIVVPNGKEQRMKDEKGLKVLKWNFTTPRDEYIEQLKTQMSSCVA 1205
T K K G + +E +K + V++ + +E I +++ +S
Sbjct: 281 STLGSKSSAAKEGAGAV----DEEDFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKH 336
Query: 1206 KWLQDEMFHSDFQHHNKALAVMVDHLESEKEGVIGCLDLILKWLTLRFFDTNTSVLMKAL 1265
W Q + A A D+ + G L K D + V+ +A
Sbjct: 337 DWEQRVNALKKIRSLLLAGAAEYDNFFQHLRLLDGAFKLSAK-------DLRSQVVREAC 389
Query: 1266 EYLKLLFTLLSEEEYHLTENEASSFIPYLVVKVGEPKDVIRKDVRAILNRMCLVYPASKM 1325
L L ++L + H A + +P + + ++ + + ++
Sbjct: 390 ITLGHLSSVLGNKFDH----GAEAIMPTIFNLIPNSAKIMATSGVVAVRLIIRHTHIPRL 445
Query: 1326 FPFIMEGTKSKNSKQRAECLEELGCLVESYGMNVCQPTPGKALKEIAVHIGDRDNAVRNA 1385
P I SK+ R C E L L++ + + + + I I D D+ R
Sbjct: 446 IPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSLERHISVLAETIKKGIHDADSEARIE 505
Query: 1386 ALNTIVTVYNVHGDQVFKLIGNLSEKDMSMLEERIKRSAKRPSAAPIKQVEEKPQRAQNI 1445
A ++ + L L L+ +K S S + Q + +Q
Sbjct: 506 ARKCYWGFHSHFSREAEHLYHTLESSYQKALQSHLKNS---DSIVSLPQSDRSSSSSQES 562
Query: 1446 SSNANMLRKGPAEDMSSKLNQARSMS 1471
+ ++ P +S+ + + S
Sbjct: 563 LNRPLSAKRSPTGSTTSRASTVSTKS 588
Score = 33.5 bits (75), Expect = 2.1
Identities = 54/246 (21%), Positives = 98/246 (39%), Gaps = 21/246 (8%)
Query: 260 DEVPQIDAYELLEAV-----EILSKLPKDFYDKI---------EAKKWQERKEALESVEV 305
D + D L EAV E L +P D D + ++ +ERK AL +
Sbjct: 1212 DAINTYDKTALKEAVFDDDMEQLRDVPIDHSDLVADLLKELSNHNERVEERKGALLELLK 1271
Query: 306 LIKNPKLEAGD--YADLVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAGHVV 363
+ + L + + ++ L + +G D + + ALA + L + +F YA +
Sbjct: 1272 ITREDSLGVWEEHFKTILLLLLETLG-DKDHSIRALALRVLREILRNQPARFKNYAELTI 1330
Query: 364 PTILEKFKEKKPQVVQALQEAIDAIFLTTTLQNISEDVLAVMDNKNPTIKQQTSLFIARS 423
LE K+ +VV+A +EA + + + + + ++ + I +
Sbjct: 1331 MKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIIQTADYPINLAAIKMQTKV 1390
Query: 424 FRHCTASTLPKSLLKPFCAALLKHINDSAPEVRDAAFEALGTALKVVGEKAVNPFLADV- 482
+L LL LL+ +++ VR A+ L V+GE + P LA +
Sbjct: 1391 VERIAKESL-LQLLVDIIPGLLQGYDNTESSVRKASVFCLVAIYSVIGED-LKPHLAQLT 1448
Query: 483 -DKLKL 487
K+KL
Sbjct: 1449 GSKMKL 1454
>gi|31563537 CLIP-associating protein 1 isoform 1 [Homo sapiens]
Length = 1538
Score = 54.3 bits (129), Expect = 1e-06
Identities = 99/541 (18%), Positives = 197/541 (36%), Gaps = 58/541 (10%)
Query: 51 GLIKKFVTDSNAVVQLKGLEAALVYVENAHVAGKTT-GEVVSGVVSKVFNQPKAKAKELG 109
GL +V SN V L G++ V K G V+ ++ ++ + + ++
Sbjct: 53 GLATSWVNSSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQ 112
Query: 110 IEICLMYIEIEKGEAVQEELLKGLDNKNPKIIVACIETLRKALSEFGSKIILLKPIIKVL 169
+ + + + V + +L G +KN + L L+ G++ + L I+ +
Sbjct: 113 TLLLKIMDQAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHI 172
Query: 170 PKLFESREKAVRDEAKLIAVEIYRWIRDALRPPLQN------------------------ 205
L VRD A VEIYR + + +R L
Sbjct: 173 CNLLGDPNSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIFTKFDEVQKSGNM 232
Query: 206 INSVQLKELEEE--------------WVKLPTSAPRPTRFLRSQQELEAKLEQQQSAGGD 251
I S K ++E K P S+ R +++ + L + SA +
Sbjct: 233 IQSANDKNFDDEDSVDGNRPSSASSTSSKAPPSSRRNVGMGTTRRLGSSTLGSKSSAAKE 292
Query: 252 AEGGGDDGD------EVPQIDAYELLEAVEILSKLPKDFYDKIEAKKWQERKEALESVEV 305
G D+ D +VP + Y + E ++K+ + D + W++R AL+ +
Sbjct: 293 GAGAVDEEDFIKAFDDVPVVQIYSSRDLEESINKIREILSD--DKHDWEQRVNALKKIRS 350
Query: 306 LIKNPKLEAGDYADLVKALK---KVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAGHV 362
L+ E ++ ++ L K+ KD +V A L L+ L KF A +
Sbjct: 351 LLLAGAAEYDNFFQHLRLLDGAFKLSAKDLRSQVVREACITLGHLSSVLGNKFDHGAEAI 410
Query: 363 VPTILEKFKEKKPQVVQALQEAIDAIFLTTTLQNISEDVLAVMDNKNPTIKQQTSLFIAR 422
+PTI + + A+ I T + + + + +K+ ++++ F+
Sbjct: 411 MPTIFNLIPNSAKIMATSGVVAVRLIIRHTHIPRLIPVITSNCTSKSVAVRRRCFEFLDL 470
Query: 423 SFRHCTASTLPKSLLKPFCAALLKHINDSAPEVRDAA---FEALGTALKVVGEKAVNPFL 479
+ +L + + + K I+D+ E R A + + E +
Sbjct: 471 LLQEWQTHSLERH-ISVLAETIKKGIHDADSEARIEARKCYWGFHSHFSREAEHLYHTLE 529
Query: 480 ADVDKLKLDKIKECSEKVELIHGKKAGLAADKKEFKPLPGRTAASGA----AGDKDTKDI 535
+ K +K V L ++ ++ + +PL + + +G+ A TK +
Sbjct: 530 SSYQKALQSHLKNSDSIVSLPQSDRSSSSSQESLNRPLSAKRSPTGSTTSRASTVSTKSV 589
Query: 536 S 536
S
Sbjct: 590 S 590
Score = 50.4 bits (119), Expect = 2e-05
Identities = 48/208 (23%), Positives = 94/208 (45%), Gaps = 28/208 (13%)
Query: 1197 KTQMSSCVAKWLQDEMFHSDFQHHNKALAVMVDHLESEKEGVIGCLDLILKWLTLRFFDT 1256
+ Q+ + + D+ +D +H L +VD L + W+ +
Sbjct: 20 RLQVGQELIDYFSDKQKSADLEHDQTMLDKLVDGLATS-------------WVN----SS 62
Query: 1257 NTSVLMKALEYLKLLFTLLSEEEYHLTENEASSFIPYLVVKVGEPKDVIRK-DVRAILNR 1315
N V++ ++ L L T L + + + + +P L+ ++G+ KD +R+ D +L
Sbjct: 63 NYKVVLLGMDILSALVTRLQDR----FKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKI 118
Query: 1316 MCLVYPASKMFPFIMEGTKSKNSKQRAE-CLEELGCLVESYGMNVCQP-TPGKALKEIAV 1373
M ++ ++ G K KN + R CL CL+ + + Q T K + I
Sbjct: 119 MDQAANPQYVWDRMLGGFKHKNFRTREGICL----CLIATLNASGAQTLTLSKIVPHICN 174
Query: 1374 HIGDRDNAVRNAALNTIVTVYNVHGDQV 1401
+GD ++ VR+AA+N++V +Y G++V
Sbjct: 175 LLGDPNSQVRDAAINSLVEIYRHVGERV 202
Score = 43.1 bits (100), Expect = 0.003
Identities = 48/246 (19%), Positives = 94/246 (38%), Gaps = 6/246 (2%)
Query: 653 TNFQVMQMKLHIV-ALIAQKGNFSKTSAQVVLDGLVDKIGDVKCGNNAKEA--MTAIAEA 709
+N++V+ + + I+ AL+ + + K VL L+D++GD K ++ + I +
Sbjct: 62 SNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKIMDQ 121
Query: 710 CMLPWTAEQVVSMAFSQKNPKNQSETLNWLSNAIKEFGFSGLNVKAFISNVKTALAATNP 769
P + F KN + + L + G L + + ++ L N
Sbjct: 122 AANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLGDPNS 181
Query: 770 AVRTAAITLLGVMYLYVGPSLRMFFEDEKPALLSQIDAEFEKMQGQSPPAPTRGISKHST 829
VR AAI L +Y +VG +R +K S+++ F K +
Sbjct: 182 QVRDAAINSLVEIYRHVGERVRADL-SKKGLPQSRLNVIFTKFDEVQKSGNMIQSANDKN 240
Query: 830 SGTDEGEDGDEPDDGSNDVVDLLPRTEISDKITSELVSKIGDKNWKIRKEGLDEVAGIIN 889
++ DG+ P S+ P + + ++G + E AG ++
Sbjct: 241 FDDEDSVDGNRPSSASSTSSKAPPSSR--RNVGMGTTRRLGSSTLGSKSSAAKEGAGAVD 298
Query: 890 DAKFIQ 895
+ FI+
Sbjct: 299 EEDFIK 304
Score = 42.7 bits (99), Expect = 0.003
Identities = 63/284 (22%), Positives = 111/284 (39%), Gaps = 34/284 (11%)
Query: 320 LVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAGHVVPTILEKFKEKKPQVVQ 379
LV L +N +V L L+ L L+ +F G V+P+++++ + K V +
Sbjct: 50 LVDGLATSWVNSSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVRE 109
Query: 380 ALQEAIDAIF-LTTTLQNISEDVLAVMDNKNPTIKQQTSLFIARSFRHCTASTLPKSLLK 438
Q + I Q + + +L +KN ++ L + + A TL S +
Sbjct: 110 QDQTLLLKIMDQAANPQYVWDRMLGGFKHKNFRTREGICLCLIATLNASGAQTLTLSKIV 169
Query: 439 PFCAALLKHINDSAPEVRDAAFEALGTALKVVGEKAVNPFLADVDKLKLDKIKECSEKVE 498
P LL D +VRDAA +L + VGE+ AD+ K L + + +
Sbjct: 170 PHICNLL---GDPNSQVRDAAINSLVEIYRHVGERV----RADLSKKGLPQSRLNVIFTK 222
Query: 499 LIHGKKAG---LAADKKEFKPLPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPP 555
+K+G +A+ K F D+D+ D + P A + + PP
Sbjct: 223 FDEVQKSGNMIQSANDKNF-------------DDEDSVDGNRP-----SSASSTSSKAPP 264
Query: 556 KKGKPAAPG-----GAGNTGTKNKKGLETKEIVEPELSIEVCEE 594
+ G G+ G+K+ E V+ E I+ ++
Sbjct: 265 SSRRNVGMGTTRRLGSSTLGSKSSAAKEGAGAVDEEDFIKAFDD 308
Score = 42.0 bits (97), Expect = 0.006
Identities = 105/566 (18%), Positives = 196/566 (34%), Gaps = 39/566 (6%)
Query: 909 LNDSNKILVQQTLNILQQLAVAMGPNIKQHVKNLGIPIITVLGDSKNNVRAAALATVNAW 968
+N SN +V ++IL L + K + + +I LGD+K++VR +
Sbjct: 59 VNSSNYKVVLLGMDILSALVTRLQDRFKAQIGTVLPSLIDRLGDAKDSVREQDQTLLLKI 118
Query: 969 AEQTGMKEWLEGEDLSEELKKENPFLRQELLGWLAEKLPTLRSTPTDLILCVPHLYSCLE 1028
+Q +++ L K +N R+ + L L + L VPH+ + L
Sbjct: 119 MDQAANPQYVWDRMLGG-FKHKNFRTREGICLCLIATLNASGAQTLTLSKIVPHICNLLG 177
Query: 1029 DRNGDVRKKAQDALPFFMMHLGYEKMAKATGKLKPTSKDQVLAMLEKAKVNMPAKPAPPT 1088
D N VR A ++L H+G A + K P S+ V+ T
Sbjct: 178 DPNSQVRDAAINSLVEIYRHVGERVRADLSKKGLPQSRLNVIF----------------T 221
Query: 1089 KATSKPMGGSAPAKFQPASAPAEDCISSSTEPKPDPKKAKAPGLSSKAKSAQG--KKMPS 1146
K G+ + ED + + +KAP SS+ G +++ S
Sbjct: 222 KFDEVQKSGNMIQSANDKNFDDEDSVDGNRPSSASSTSSKAPP-SSRRNVGMGTTRRLGS 280
Query: 1147 KT-SLKEDEDKSGPIFIVVPNGKEQRMKDEKGLKVLKWNFTTPRDEYIEQLKTQMSSCVA 1205
T K K G + +E +K + V++ + +E I +++ +S
Sbjct: 281 STLGSKSSAAKEGAGAV----DEEDFIKAFDDVPVVQIYSSRDLEESINKIREILSDDKH 336
Query: 1206 KWLQDEMFHSDFQHHNKALAVMVDHLESEKEGVIGCLDLILKWLTLRFFDTNTSVLMKAL 1265
W Q + A A D+ + G L K D + V+ +A
Sbjct: 337 DWEQRVNALKKIRSLLLAGAAEYDNFFQHLRLLDGAFKLSAK-------DLRSQVVREAC 389
Query: 1266 EYLKLLFTLLSEEEYHLTENEASSFIPYLVVKVGEPKDVIRKDVRAILNRMCLVYPASKM 1325
L L ++L + H A + +P + + ++ + + ++
Sbjct: 390 ITLGHLSSVLGNKFDH----GAEAIMPTIFNLIPNSAKIMATSGVVAVRLIIRHTHIPRL 445
Query: 1326 FPFIMEGTKSKNSKQRAECLEELGCLVESYGMNVCQPTPGKALKEIAVHIGDRDNAVRNA 1385
P I SK+ R C E L L++ + + + + I I D D+ R
Sbjct: 446 IPVITSNCTSKSVAVRRRCFEFLDLLLQEWQTHSLERHISVLAETIKKGIHDADSEARIE 505
Query: 1386 ALNTIVTVYNVHGDQVFKLIGNLSEKDMSMLEERIKRSAKRPSAAPIKQVEEKPQRAQNI 1445
A ++ + L L L+ +K S S + Q + +Q
Sbjct: 506 ARKCYWGFHSHFSREAEHLYHTLESSYQKALQSHLKNS---DSIVSLPQSDRSSSSSQES 562
Query: 1446 SSNANMLRKGPAEDMSSKLNQARSMS 1471
+ ++ P +S+ + + S
Sbjct: 563 LNRPLSAKRSPTGSTTSRASTVSTKS 588
Score = 33.5 bits (75), Expect = 2.1
Identities = 54/246 (21%), Positives = 98/246 (39%), Gaps = 21/246 (8%)
Query: 260 DEVPQIDAYELLEAV-----EILSKLPKDFYDKI---------EAKKWQERKEALESVEV 305
D + D L EAV E L +P D D + ++ +ERK AL +
Sbjct: 1271 DAINTYDKTALKEAVFDDDMEQLRDVPIDHSDLVADLLKELSNHNERVEERKGALLELLK 1330
Query: 306 LIKNPKLEAGD--YADLVKALKKVVGKDTNVMLVALAAKCLTGLAVGLRKKFGQYAGHVV 363
+ + L + + ++ L + +G D + + ALA + L + +F YA +
Sbjct: 1331 ITREDSLGVWEEHFKTILLLLLETLG-DKDHSIRALALRVLREILRNQPARFKNYAELTI 1389
Query: 364 PTILEKFKEKKPQVVQALQEAIDAIFLTTTLQNISEDVLAVMDNKNPTIKQQTSLFIARS 423
LE K+ +VV+A +EA + + + + + ++ + I +
Sbjct: 1390 MKTLEAHKDSHKEVVRAAEEAASTLASSIHPEQCIKVLCPIIQTADYPINLAAIKMQTKV 1449
Query: 424 FRHCTASTLPKSLLKPFCAALLKHINDSAPEVRDAAFEALGTALKVVGEKAVNPFLADV- 482
+L LL LL+ +++ VR A+ L V+GE + P LA +
Sbjct: 1450 VERIAKESL-LQLLVDIIPGLLQGYDNTESSVRKASVFCLVAIYSVIGED-LKPHLAQLT 1507
Query: 483 -DKLKL 487
K+KL
Sbjct: 1508 GSKMKL 1513
>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
sapiens]
Length = 1424
Score = 43.1 bits (100), Expect = 0.003
Identities = 22/60 (36%), Positives = 24/60 (40%)
Query: 517 LPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
LPG G G+ + P P P G P K GKP PG AG G K KG
Sbjct: 1356 LPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKG 1415
Score = 38.5 bits (88), Expect = 0.066
Identities = 20/60 (33%), Positives = 24/60 (40%), Gaps = 2/60 (3%)
Query: 517 LPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
+PG G AG + +S P PGP P G P +G P PG G G G
Sbjct: 632 VPGAPGPPGEAGPRGELSVSTPVPGP--PGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPG 689
Score = 35.0 bits (79), Expect = 0.73
Identities = 19/59 (32%), Positives = 26/59 (44%)
Query: 519 GRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKGL 577
G+ GA G+K K P P +K G P +G PG G TG+K +G+
Sbjct: 37 GQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGI 95
Score = 35.0 bits (79), Expect = 0.73
Identities = 25/63 (39%), Positives = 28/63 (44%), Gaps = 3/63 (4%)
Query: 518 PGRTAASGAAGDKDTK-DISAP-KPGPLKKA-PAAKAGGPPKKGKPAAPGGAGNTGTKNK 574
PG T G GD K ++ P PG L A P G P G P PG G+ G K
Sbjct: 1067 PGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGI 1126
Query: 575 KGL 577
KGL
Sbjct: 1127 KGL 1129
Score = 34.7 bits (78), Expect = 0.95
Identities = 21/63 (33%), Positives = 25/63 (39%), Gaps = 5/63 (7%)
Query: 514 FKPLPGRTAASGAAGDKDTKDISA-----PKPGPLKKAPAAKAGGPPKKGKPAAPGGAGN 568
F LPGR A G AG + I PG + G P +G P APG G
Sbjct: 1199 FPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGP 1258
Query: 569 TGT 571
G+
Sbjct: 1259 PGS 1261
Score = 32.3 bits (72), Expect = 4.7
Identities = 17/53 (32%), Positives = 19/53 (35%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTG 570
PGR G G K + PK G P G P +PG AG G
Sbjct: 562 PGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAG 614
Score = 32.3 bits (72), Expect = 4.7
Identities = 17/58 (29%), Positives = 20/58 (34%)
Query: 519 GRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
G G G K K + P P + G P + G PG GN G KG
Sbjct: 970 GNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKG 1027
Score = 32.3 bits (72), Expect = 4.7
Identities = 20/64 (31%), Positives = 25/64 (39%), Gaps = 4/64 (6%)
Query: 519 GRTAASGAAGDKDTKDISAPKPGPLKKAPAAKA----GGPPKKGKPAAPGGAGNTGTKNK 574
GR G AG+K + PGP A A G P G P G G+ G +
Sbjct: 1158 GRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGP 1217
Query: 575 KGLE 578
G+E
Sbjct: 1218 TGIE 1221
>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
sapiens]
Length = 1494
Score = 43.1 bits (100), Expect = 0.003
Identities = 22/60 (36%), Positives = 24/60 (40%)
Query: 517 LPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
LPG G G+ + P P P G P K GKP PG AG G K KG
Sbjct: 1356 LPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKG 1415
Score = 38.5 bits (88), Expect = 0.066
Identities = 20/60 (33%), Positives = 24/60 (40%), Gaps = 2/60 (3%)
Query: 517 LPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
+PG G AG + +S P PGP P G P +G P PG G G G
Sbjct: 632 VPGAPGPPGEAGPRGELSVSTPVPGP--PGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPG 689
Score = 35.0 bits (79), Expect = 0.73
Identities = 19/59 (32%), Positives = 26/59 (44%)
Query: 519 GRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKGL 577
G+ GA G+K K P P +K G P +G PG G TG+K +G+
Sbjct: 37 GQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGI 95
Score = 35.0 bits (79), Expect = 0.73
Identities = 25/63 (39%), Positives = 28/63 (44%), Gaps = 3/63 (4%)
Query: 518 PGRTAASGAAGDKDTK-DISAP-KPGPLKKA-PAAKAGGPPKKGKPAAPGGAGNTGTKNK 574
PG T G GD K ++ P PG L A P G P G P PG G+ G K
Sbjct: 1067 PGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGI 1126
Query: 575 KGL 577
KGL
Sbjct: 1127 KGL 1129
Score = 34.7 bits (78), Expect = 0.95
Identities = 21/63 (33%), Positives = 25/63 (39%), Gaps = 5/63 (7%)
Query: 514 FKPLPGRTAASGAAGDKDTKDISA-----PKPGPLKKAPAAKAGGPPKKGKPAAPGGAGN 568
F LPGR A G AG + I PG + G P +G P APG G
Sbjct: 1199 FPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGP 1258
Query: 569 TGT 571
G+
Sbjct: 1259 PGS 1261
Score = 32.3 bits (72), Expect = 4.7
Identities = 17/53 (32%), Positives = 19/53 (35%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTG 570
PGR G G K + PK G P G P +PG AG G
Sbjct: 562 PGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAG 614
Score = 32.3 bits (72), Expect = 4.7
Identities = 17/58 (29%), Positives = 20/58 (34%)
Query: 519 GRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
G G G K K + P P + G P + G PG GN G KG
Sbjct: 970 GNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKG 1027
Score = 32.3 bits (72), Expect = 4.7
Identities = 20/64 (31%), Positives = 25/64 (39%), Gaps = 4/64 (6%)
Query: 519 GRTAASGAAGDKDTKDISAPKPGPLKKAPAAKA----GGPPKKGKPAAPGGAGNTGTKNK 574
GR G AG+K + PGP A A G P G P G G+ G +
Sbjct: 1158 GRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGP 1217
Query: 575 KGLE 578
G+E
Sbjct: 1218 TGIE 1221
Score = 31.6 bits (70), Expect = 8.0
Identities = 21/59 (35%), Positives = 24/59 (40%), Gaps = 6/59 (10%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
PG G G K KD PGP A + G KG+P G G G K K+G
Sbjct: 1381 PGNLGPCGPRG-KPGKDGKPGTPGP-----AGEKGNKGSKGEPGPAGSDGLPGLKGKRG 1433
>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
sapiens]
Length = 1637
Score = 43.1 bits (100), Expect = 0.003
Identities = 22/60 (36%), Positives = 24/60 (40%)
Query: 517 LPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
LPG G G+ + P P P G P K GKP PG AG G K KG
Sbjct: 1356 LPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKG 1415
Score = 38.5 bits (88), Expect = 0.066
Identities = 20/60 (33%), Positives = 24/60 (40%), Gaps = 2/60 (3%)
Query: 517 LPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
+PG G AG + +S P PGP P G P +G P PG G G G
Sbjct: 632 VPGAPGPPGEAGPRGELSVSTPVPGP--PGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPG 689
Score = 35.0 bits (79), Expect = 0.73
Identities = 19/59 (32%), Positives = 26/59 (44%)
Query: 519 GRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKGL 577
G+ GA G+K K P P +K G P +G PG G TG+K +G+
Sbjct: 37 GQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGI 95
Score = 35.0 bits (79), Expect = 0.73
Identities = 25/63 (39%), Positives = 28/63 (44%), Gaps = 3/63 (4%)
Query: 518 PGRTAASGAAGDKDTK-DISAP-KPGPLKKA-PAAKAGGPPKKGKPAAPGGAGNTGTKNK 574
PG T G GD K ++ P PG L A P G P G P PG G+ G K
Sbjct: 1067 PGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGI 1126
Query: 575 KGL 577
KGL
Sbjct: 1127 KGL 1129
Score = 34.7 bits (78), Expect = 0.95
Identities = 21/63 (33%), Positives = 25/63 (39%), Gaps = 5/63 (7%)
Query: 514 FKPLPGRTAASGAAGDKDTKDISA-----PKPGPLKKAPAAKAGGPPKKGKPAAPGGAGN 568
F LPGR A G AG + I PG + G P +G P APG G
Sbjct: 1199 FPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGP 1258
Query: 569 TGT 571
G+
Sbjct: 1259 PGS 1261
Score = 32.3 bits (72), Expect = 4.7
Identities = 17/53 (32%), Positives = 19/53 (35%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTG 570
PGR G G K + PK G P G P +PG AG G
Sbjct: 562 PGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAG 614
Score = 32.3 bits (72), Expect = 4.7
Identities = 17/58 (29%), Positives = 20/58 (34%)
Query: 519 GRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
G G G K K + P P + G P + G PG GN G KG
Sbjct: 970 GNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKG 1027
Score = 32.3 bits (72), Expect = 4.7
Identities = 20/64 (31%), Positives = 25/64 (39%), Gaps = 4/64 (6%)
Query: 519 GRTAASGAAGDKDTKDISAPKPGPLKKAPAAKA----GGPPKKGKPAAPGGAGNTGTKNK 574
GR G AG+K + PGP A A G P G P G G+ G +
Sbjct: 1158 GRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGP 1217
Query: 575 KGLE 578
G+E
Sbjct: 1218 TGIE 1221
Score = 31.6 bits (70), Expect = 8.0
Identities = 21/59 (35%), Positives = 24/59 (40%), Gaps = 6/59 (10%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
PG G G K KD PGP A + G KG+P G G G K K+G
Sbjct: 1381 PGNLGPCGPRG-KPGKDGKPGTPGP-----AGEKGNKGSKGEPGPAGSDGLPGLKGKRG 1433
>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
sapiens]
Length = 1670
Score = 43.1 bits (100), Expect = 0.003
Identities = 22/60 (36%), Positives = 24/60 (40%)
Query: 517 LPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
LPG G G+ + P P P G P K GKP PG AG G K KG
Sbjct: 1356 LPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKG 1415
Score = 38.5 bits (88), Expect = 0.066
Identities = 20/60 (33%), Positives = 24/60 (40%), Gaps = 2/60 (3%)
Query: 517 LPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
+PG G AG + +S P PGP P G P +G P PG G G G
Sbjct: 632 VPGAPGPPGEAGPRGELSVSTPVPGP--PGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPG 689
Score = 35.0 bits (79), Expect = 0.73
Identities = 19/59 (32%), Positives = 26/59 (44%)
Query: 519 GRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKGL 577
G+ GA G+K K P P +K G P +G PG G TG+K +G+
Sbjct: 37 GQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGI 95
Score = 35.0 bits (79), Expect = 0.73
Identities = 25/63 (39%), Positives = 28/63 (44%), Gaps = 3/63 (4%)
Query: 518 PGRTAASGAAGDKDTK-DISAP-KPGPLKKA-PAAKAGGPPKKGKPAAPGGAGNTGTKNK 574
PG T G GD K ++ P PG L A P G P G P PG G+ G K
Sbjct: 1067 PGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGI 1126
Query: 575 KGL 577
KGL
Sbjct: 1127 KGL 1129
Score = 34.7 bits (78), Expect = 0.95
Identities = 21/63 (33%), Positives = 25/63 (39%), Gaps = 5/63 (7%)
Query: 514 FKPLPGRTAASGAAGDKDTKDISA-----PKPGPLKKAPAAKAGGPPKKGKPAAPGGAGN 568
F LPGR A G AG + I PG + G P +G P APG G
Sbjct: 1199 FPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGP 1258
Query: 569 TGT 571
G+
Sbjct: 1259 PGS 1261
Score = 32.3 bits (72), Expect = 4.7
Identities = 17/53 (32%), Positives = 19/53 (35%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTG 570
PGR G G K + PK G P G P +PG AG G
Sbjct: 562 PGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAG 614
Score = 32.3 bits (72), Expect = 4.7
Identities = 17/58 (29%), Positives = 20/58 (34%)
Query: 519 GRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
G G G K K + P P + G P + G PG GN G KG
Sbjct: 970 GNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIPGSMGNMGMPGSKG 1027
Score = 32.3 bits (72), Expect = 4.7
Identities = 20/64 (31%), Positives = 25/64 (39%), Gaps = 4/64 (6%)
Query: 519 GRTAASGAAGDKDTKDISAPKPGPLKKAPAAKA----GGPPKKGKPAAPGGAGNTGTKNK 574
GR G AG+K + PGP A A G P G P G G+ G +
Sbjct: 1158 GRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGP 1217
Query: 575 KGLE 578
G+E
Sbjct: 1218 TGIE 1221
Score = 31.6 bits (70), Expect = 8.0
Identities = 21/59 (35%), Positives = 24/59 (40%), Gaps = 6/59 (10%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
PG G G K KD PGP A + G KG+P G G G K K+G
Sbjct: 1381 PGNLGPCGPRG-KPGKDGKPGTPGP-----AGEKGNKGSKGEPGPAGSDGLPGLKGKRG 1433
>gi|50511941 EMI domain containing 1 [Homo sapiens]
Length = 443
Score = 41.6 bits (96), Expect = 0.008
Identities = 28/111 (25%), Positives = 45/111 (40%), Gaps = 19/111 (17%)
Query: 485 LKLDKIKECSEKVELIHGKKAGLAADKKEFKPLP----------GRTAASGAAGDKDTKD 534
L K+ E +E+++++ K L ++ P P G A G+ GD +D
Sbjct: 137 LNCSKVSELTERLKVLEAKMTMLTVIEQPVPPTPATPEDPAPLWGPPPAQGSPGDGGLQD 196
Query: 535 I---------SAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
+ PK + P G P +G P +PG AG GT ++G
Sbjct: 197 QVGAWGLPGPTGPKGDAGSRGPMGMRGPPGPQGPPGSPGRAGAVGTPGERG 247
Score = 32.0 bits (71), Expect = 6.1
Identities = 20/58 (34%), Positives = 24/58 (41%), Gaps = 5/58 (8%)
Query: 517 LPGRTAASGAAGDKDTKDISAPKPGPL----KKAPAAKAGGPPKKGKPAAPGGAGNTG 570
LPG T G AG + + P PGP A G P ++G P PG G G
Sbjct: 203 LPGPTGPKGDAGSRGPMGMRGP-PGPQGPPGSPGRAGAVGTPGERGPPGPPGPPGPPG 259
>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein
[Homo sapiens]
Length = 1650
Score = 41.2 bits (95), Expect = 0.010
Identities = 21/59 (35%), Positives = 25/59 (42%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
PG G AG + TK P P K PA G P ++G P GG G G + G
Sbjct: 865 PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSG 923
Score = 34.3 bits (77), Expect = 1.2
Identities = 20/63 (31%), Positives = 26/63 (41%), Gaps = 3/63 (4%)
Query: 517 LPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAG--GPP-KKGKPAAPGGAGNTGTKN 573
LPG G G++ P P ++ A G GPP + G PG AG G
Sbjct: 906 LPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPG 965
Query: 574 KKG 576
+KG
Sbjct: 966 EKG 968
Score = 33.9 bits (76), Expect = 1.6
Identities = 25/72 (34%), Positives = 31/72 (43%), Gaps = 20/72 (27%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGP--LKKAPAA-----------KAGGPPKKGKPAAPG 564
PG+T G AG A KPGP L+ P + +AG P G P PG
Sbjct: 1261 PGKTGPVGPAGP-------AGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPG 1313
Query: 565 GAGNTGTKNKKG 576
G+ G K +KG
Sbjct: 1314 LRGDAGAKGEKG 1325
Score = 33.1 bits (74), Expect = 2.8
Identities = 22/60 (36%), Positives = 26/60 (43%), Gaps = 6/60 (10%)
Query: 517 LPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
LPG + G GD P PGP + PA G +G P GG GN G +KG
Sbjct: 1074 LPGPSGEKGETGDVGPMGPPGP-PGP--RGPAGPNGADGPQGPP---GGVGNLGPPGEKG 1127
Score = 32.7 bits (73), Expect = 3.6
Identities = 26/83 (31%), Positives = 35/83 (42%), Gaps = 12/83 (14%)
Query: 508 AADKKEFKPLPGRTAASGAAGDKDTKDISAPKPGPLKKA----PAAKA----GGPPKKGK 559
A +K L G G G+K + + P+ P +K P A GGPP
Sbjct: 1320 AKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPG 1379
Query: 560 PAAPGGA----GNTGTKNKKGLE 578
PA P GA G G K +KG++
Sbjct: 1380 PAGPKGAKGATGPGGPKGEKGVQ 1402
Score = 32.3 bits (72), Expect = 4.7
Identities = 22/73 (30%), Positives = 26/73 (35%), Gaps = 2/73 (2%)
Query: 506 GLAADKKEFKP--LPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAP 563
G D E P LPG + G G K I P P G +G+P P
Sbjct: 503 GERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPP 562
Query: 564 GGAGNTGTKNKKG 576
G G GT+ G
Sbjct: 563 GQQGTPGTQGLPG 575
Score = 31.6 bits (70), Expect = 8.0
Identities = 23/65 (35%), Positives = 27/65 (41%), Gaps = 7/65 (10%)
Query: 518 PGRTAASGAAGDKDTKDISAPK--PGPLK---KAPAAKAGGPPKKGKPAAPGGAGNTGTK 572
PG G AG K P PGP + AA +GGP G P PG G G
Sbjct: 901 PGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPI--GPPGRPGPQGPPGAA 958
Query: 573 NKKGL 577
+KG+
Sbjct: 959 GEKGV 963
>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein
[Homo sapiens]
Length = 1629
Score = 41.2 bits (95), Expect = 0.010
Identities = 21/59 (35%), Positives = 25/59 (42%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
PG G AG + TK P P K PA G P ++G P GG G G + G
Sbjct: 844 PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSG 902
Score = 34.3 bits (77), Expect = 1.2
Identities = 20/63 (31%), Positives = 26/63 (41%), Gaps = 3/63 (4%)
Query: 517 LPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAG--GPP-KKGKPAAPGGAGNTGTKN 573
LPG G G++ P P ++ A G GPP + G PG AG G
Sbjct: 885 LPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPG 944
Query: 574 KKG 576
+KG
Sbjct: 945 EKG 947
Score = 33.9 bits (76), Expect = 1.6
Identities = 25/72 (34%), Positives = 31/72 (43%), Gaps = 20/72 (27%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGP--LKKAPAA-----------KAGGPPKKGKPAAPG 564
PG+T G AG A KPGP L+ P + +AG P G P PG
Sbjct: 1240 PGKTGPVGPAGP-------AGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPG 1292
Query: 565 GAGNTGTKNKKG 576
G+ G K +KG
Sbjct: 1293 LRGDAGAKGEKG 1304
Score = 33.1 bits (74), Expect = 2.8
Identities = 22/60 (36%), Positives = 26/60 (43%), Gaps = 6/60 (10%)
Query: 517 LPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
LPG + G GD P PGP + PA G +G P GG GN G +KG
Sbjct: 1053 LPGPSGEKGETGDVGPMGPPGP-PGP--RGPAGPNGADGPQGPP---GGVGNLGPPGEKG 1106
Score = 32.7 bits (73), Expect = 3.6
Identities = 26/83 (31%), Positives = 35/83 (42%), Gaps = 12/83 (14%)
Query: 508 AADKKEFKPLPGRTAASGAAGDKDTKDISAPKPGPLKKA----PAAKA----GGPPKKGK 559
A +K L G G G+K + + P+ P +K P A GGPP
Sbjct: 1299 AKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPG 1358
Query: 560 PAAPGGA----GNTGTKNKKGLE 578
PA P GA G G K +KG++
Sbjct: 1359 PAGPKGAKGATGPGGPKGEKGVQ 1381
Score = 32.3 bits (72), Expect = 4.7
Identities = 22/73 (30%), Positives = 26/73 (35%), Gaps = 2/73 (2%)
Query: 506 GLAADKKEFKP--LPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAP 563
G D E P LPG + G G K I P P G +G+P P
Sbjct: 482 GERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPP 541
Query: 564 GGAGNTGTKNKKG 576
G G GT+ G
Sbjct: 542 GQQGTPGTQGLPG 554
Score = 31.6 bits (70), Expect = 8.0
Identities = 23/65 (35%), Positives = 27/65 (41%), Gaps = 7/65 (10%)
Query: 518 PGRTAASGAAGDKDTKDISAPK--PGPLK---KAPAAKAGGPPKKGKPAAPGGAGNTGTK 572
PG G AG K P PGP + AA +GGP G P PG G G
Sbjct: 880 PGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPI--GPPGRPGPQGPPGAA 937
Query: 573 NKKGL 577
+KG+
Sbjct: 938 GEKGV 942
>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
sapiens]
Length = 1736
Score = 41.2 bits (95), Expect = 0.010
Identities = 21/59 (35%), Positives = 25/59 (42%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
PG G AG + TK P P K PA G P ++G P GG G G + G
Sbjct: 951 PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSG 1009
Score = 34.3 bits (77), Expect = 1.2
Identities = 20/63 (31%), Positives = 26/63 (41%), Gaps = 3/63 (4%)
Query: 517 LPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAG--GPP-KKGKPAAPGGAGNTGTKN 573
LPG G G++ P P ++ A G GPP + G PG AG G
Sbjct: 992 LPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPG 1051
Query: 574 KKG 576
+KG
Sbjct: 1052 EKG 1054
Score = 33.9 bits (76), Expect = 1.6
Identities = 25/72 (34%), Positives = 31/72 (43%), Gaps = 20/72 (27%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGP--LKKAPAA-----------KAGGPPKKGKPAAPG 564
PG+T G AG A KPGP L+ P + +AG P G P PG
Sbjct: 1347 PGKTGPVGPAGP-------AGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPG 1399
Query: 565 GAGNTGTKNKKG 576
G+ G K +KG
Sbjct: 1400 LRGDAGAKGEKG 1411
Score = 33.1 bits (74), Expect = 2.8
Identities = 22/60 (36%), Positives = 26/60 (43%), Gaps = 6/60 (10%)
Query: 517 LPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
LPG + G GD P PGP + PA G +G P GG GN G +KG
Sbjct: 1160 LPGPSGEKGETGDVGPMGPPGP-PGP--RGPAGPNGADGPQGPP---GGVGNLGPPGEKG 1213
Score = 32.7 bits (73), Expect = 3.6
Identities = 26/83 (31%), Positives = 35/83 (42%), Gaps = 12/83 (14%)
Query: 508 AADKKEFKPLPGRTAASGAAGDKDTKDISAPKPGPLKKA----PAAKA----GGPPKKGK 559
A +K L G G G+K + + P+ P +K P A GGPP
Sbjct: 1406 AKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPG 1465
Query: 560 PAAPGGA----GNTGTKNKKGLE 578
PA P GA G G K +KG++
Sbjct: 1466 PAGPKGAKGATGPGGPKGEKGVQ 1488
Score = 32.3 bits (72), Expect = 4.7
Identities = 22/73 (30%), Positives = 26/73 (35%), Gaps = 2/73 (2%)
Query: 506 GLAADKKEFKP--LPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAP 563
G D E P LPG + G G K I P P G +G+P P
Sbjct: 589 GERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPP 648
Query: 564 GGAGNTGTKNKKG 576
G G GT+ G
Sbjct: 649 GQQGTPGTQGLPG 661
Score = 31.6 bits (70), Expect = 8.0
Identities = 23/65 (35%), Positives = 27/65 (41%), Gaps = 7/65 (10%)
Query: 518 PGRTAASGAAGDKDTKDISAPK--PGPLK---KAPAAKAGGPPKKGKPAAPGGAGNTGTK 572
PG G AG K P PGP + AA +GGP G P PG G G
Sbjct: 987 PGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPI--GPPGRPGPQGPPGAA 1044
Query: 573 NKKGL 577
+KG+
Sbjct: 1045 GEKGV 1049
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 40.8 bits (94), Expect = 0.013
Identities = 23/60 (38%), Positives = 28/60 (46%), Gaps = 3/60 (5%)
Query: 519 GRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKGLE 578
GRT +GAAG + P P P AGGP G P A G AG TG + +G +
Sbjct: 333 GRTGPAGAAGARGNDGQPGPAGPP---GPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQ 389
Score = 36.2 bits (82), Expect = 0.33
Identities = 21/69 (30%), Positives = 29/69 (42%), Gaps = 6/69 (8%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAG------GPPKKGKPAAPGGAGNTGT 571
PG A G G ++ PK P ++ P+ AG P + G+P PG G TG
Sbjct: 506 PGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGR 565
Query: 572 KNKKGLETK 580
G + K
Sbjct: 566 PGDAGPQGK 574
Score = 36.2 bits (82), Expect = 0.33
Identities = 26/72 (36%), Positives = 32/72 (44%), Gaps = 7/72 (9%)
Query: 505 AGLAADKKEFKPLPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPG 564
AG +K E P PG ++GA G + + P PGP A AG P G+P A G
Sbjct: 797 AGANGEKGEVGP-PGPAGSAGARGAPGERGETGP-PGP-----AGFAGPPGADGQPGAKG 849
Query: 565 GAGNTGTKNKKG 576
G G K G
Sbjct: 850 EQGEAGQKGDAG 861
Score = 35.8 bits (81), Expect = 0.43
Identities = 22/64 (34%), Positives = 32/64 (50%), Gaps = 3/64 (4%)
Query: 518 PGRTAASGAAGDK-DTKDISAP-KPGPL-KKAPAAKAGGPPKKGKPAAPGGAGNTGTKNK 574
PGR A+G GD+ +T + AP PGP PA G +G+ A G G +G
Sbjct: 1046 PGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGA 1105
Query: 575 KGLE 578
+G++
Sbjct: 1106 RGIQ 1109
Score = 35.4 bits (80), Expect = 0.56
Identities = 19/64 (29%), Positives = 25/64 (39%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKGL 577
PG SGA G + ++ PK + P G P G+ PG GN G G
Sbjct: 863 PGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGP 922
Query: 578 ETKE 581
K+
Sbjct: 923 SGKD 926
Score = 33.9 bits (76), Expect = 1.6
Identities = 25/72 (34%), Positives = 33/72 (45%), Gaps = 12/72 (16%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPL-KKAPAAKAGGPPKKGKPAA---PGGAGNTGTKN 573
PG+ A GA+GD+ PGP+ AG P ++G P A PG G G K
Sbjct: 1004 PGKQGAPGASGDRGP-------PGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKG 1056
Query: 574 KKGLETKEIVEP 585
+G ET + P
Sbjct: 1057 DRG-ETGAVGAP 1067
Score = 33.5 bits (75), Expect = 2.1
Identities = 17/59 (28%), Positives = 21/59 (35%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
PG +G G K + P A + G P G P PG G +G KG
Sbjct: 872 PGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKG 930
Score = 33.1 bits (74), Expect = 2.8
Identities = 21/66 (31%), Positives = 26/66 (39%), Gaps = 3/66 (4%)
Query: 514 FKPLPGRTAASGAAGDKDTKDISAPK--PG-PLKKAPAAKAGGPPKKGKPAAPGGAGNTG 570
F PG +G G + + P+ PG P PA +G P G P A G AG G
Sbjct: 367 FPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPG 426
Query: 571 TKNKKG 576
G
Sbjct: 427 IAGAPG 432
Score = 33.1 bits (74), Expect = 2.8
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 16/74 (21%)
Query: 517 LPGRTAASGAAGDK-DTKDISAPKP-------------GPLKKAPAAKAGGPPKKGKPAA 562
+PG A+G AG K D D+ P GP+ P AG +KG+
Sbjct: 751 MPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPI--GPPGPAGANGEKGEVGP 808
Query: 563 PGGAGNTGTKNKKG 576
PG AG+ G + G
Sbjct: 809 PGPAGSAGARGAPG 822
Score = 32.7 bits (73), Expect = 3.6
Identities = 22/59 (37%), Positives = 29/59 (49%), Gaps = 3/59 (5%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
PGR + GA G +D +A G + A A G P G P +PG AG TG + +G
Sbjct: 1034 PGREGSPGADGPPG-RDGAAGVKGDRGETGAVGAPGAP--GPPGSPGPAGPTGKQGDRG 1089
Score = 32.0 bits (71), Expect = 6.1
Identities = 23/65 (35%), Positives = 26/65 (40%), Gaps = 8/65 (12%)
Query: 518 PGRTAASGAAGDKDTKDISAPK--PGPL----KKAPAAKAGGPPKKGKPAAPGGAGNTGT 571
PG G GD KDI PK PGP ++ P G +KG P G G GT
Sbjct: 100 PGPKGQKGEPGD--IKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGT 157
Query: 572 KNKKG 576
G
Sbjct: 158 PGNPG 162
Score = 32.0 bits (71), Expect = 6.1
Identities = 18/59 (30%), Positives = 23/59 (38%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
PG +GA+G+ T I K A G P +G P G G G K + G
Sbjct: 398 PGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTG 456
Score = 32.0 bits (71), Expect = 6.1
Identities = 19/60 (31%), Positives = 25/60 (41%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKGL 577
PG SG G K + S P + AG P +KG+P G +G G +GL
Sbjct: 917 PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGL 976
Score = 31.6 bits (70), Expect = 8.0
Identities = 18/59 (30%), Positives = 20/59 (33%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
PG G G T PK P G P +G P G AG G K +G
Sbjct: 710 PGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRG 768
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 40.8 bits (94), Expect = 0.013
Identities = 23/60 (38%), Positives = 28/60 (46%), Gaps = 3/60 (5%)
Query: 519 GRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKGLE 578
GRT +GAAG + P P P AGGP G P A G AG TG + +G +
Sbjct: 264 GRTGPAGAAGARGNDGQPGPAGPP---GPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQ 320
Score = 36.2 bits (82), Expect = 0.33
Identities = 21/69 (30%), Positives = 29/69 (42%), Gaps = 6/69 (8%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAG------GPPKKGKPAAPGGAGNTGT 571
PG A G G ++ PK P ++ P+ AG P + G+P PG G TG
Sbjct: 437 PGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGR 496
Query: 572 KNKKGLETK 580
G + K
Sbjct: 497 PGDAGPQGK 505
Score = 36.2 bits (82), Expect = 0.33
Identities = 26/72 (36%), Positives = 32/72 (44%), Gaps = 7/72 (9%)
Query: 505 AGLAADKKEFKPLPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPG 564
AG +K E P PG ++GA G + + P PGP A AG P G+P A G
Sbjct: 728 AGANGEKGEVGP-PGPAGSAGARGAPGERGETGP-PGP-----AGFAGPPGADGQPGAKG 780
Query: 565 GAGNTGTKNKKG 576
G G K G
Sbjct: 781 EQGEAGQKGDAG 792
Score = 35.8 bits (81), Expect = 0.43
Identities = 22/64 (34%), Positives = 32/64 (50%), Gaps = 3/64 (4%)
Query: 518 PGRTAASGAAGDK-DTKDISAP-KPGPL-KKAPAAKAGGPPKKGKPAAPGGAGNTGTKNK 574
PGR A+G GD+ +T + AP PGP PA G +G+ A G G +G
Sbjct: 977 PGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGA 1036
Query: 575 KGLE 578
+G++
Sbjct: 1037 RGIQ 1040
Score = 35.4 bits (80), Expect = 0.56
Identities = 19/64 (29%), Positives = 25/64 (39%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKGL 577
PG SGA G + ++ PK + P G P G+ PG GN G G
Sbjct: 794 PGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGP 853
Query: 578 ETKE 581
K+
Sbjct: 854 SGKD 857
Score = 33.9 bits (76), Expect = 1.6
Identities = 25/72 (34%), Positives = 33/72 (45%), Gaps = 12/72 (16%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPL-KKAPAAKAGGPPKKGKPAA---PGGAGNTGTKN 573
PG+ A GA+GD+ PGP+ AG P ++G P A PG G G K
Sbjct: 935 PGKQGAPGASGDRGP-------PGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKG 987
Query: 574 KKGLETKEIVEP 585
+G ET + P
Sbjct: 988 DRG-ETGAVGAP 998
Score = 33.5 bits (75), Expect = 2.1
Identities = 17/59 (28%), Positives = 21/59 (35%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
PG +G G K + P A + G P G P PG G +G KG
Sbjct: 803 PGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKG 861
Score = 33.1 bits (74), Expect = 2.8
Identities = 21/66 (31%), Positives = 26/66 (39%), Gaps = 3/66 (4%)
Query: 514 FKPLPGRTAASGAAGDKDTKDISAPK--PG-PLKKAPAAKAGGPPKKGKPAAPGGAGNTG 570
F PG +G G + + P+ PG P PA +G P G P A G AG G
Sbjct: 298 FPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPG 357
Query: 571 TKNKKG 576
G
Sbjct: 358 IAGAPG 363
Score = 33.1 bits (74), Expect = 2.8
Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 16/74 (21%)
Query: 517 LPGRTAASGAAGDK-DTKDISAPKP-------------GPLKKAPAAKAGGPPKKGKPAA 562
+PG A+G AG K D D+ P GP+ P AG +KG+
Sbjct: 682 MPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPI--GPPGPAGANGEKGEVGP 739
Query: 563 PGGAGNTGTKNKKG 576
PG AG+ G + G
Sbjct: 740 PGPAGSAGARGAPG 753
Score = 32.7 bits (73), Expect = 3.6
Identities = 22/59 (37%), Positives = 29/59 (49%), Gaps = 3/59 (5%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
PGR + GA G +D +A G + A A G P G P +PG AG TG + +G
Sbjct: 965 PGREGSPGADGPPG-RDGAAGVKGDRGETGAVGAPGAP--GPPGSPGPAGPTGKQGDRG 1020
Score = 32.0 bits (71), Expect = 6.1
Identities = 23/65 (35%), Positives = 26/65 (40%), Gaps = 8/65 (12%)
Query: 518 PGRTAASGAAGDKDTKDISAPK--PGPL----KKAPAAKAGGPPKKGKPAAPGGAGNTGT 571
PG G GD KDI PK PGP ++ P G +KG P G G GT
Sbjct: 31 PGPKGQKGEPGD--IKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGT 88
Query: 572 KNKKG 576
G
Sbjct: 89 PGNPG 93
Score = 32.0 bits (71), Expect = 6.1
Identities = 18/59 (30%), Positives = 23/59 (38%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
PG +GA+G+ T I K A G P +G P G G G K + G
Sbjct: 329 PGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTG 387
Score = 32.0 bits (71), Expect = 6.1
Identities = 19/60 (31%), Positives = 25/60 (41%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKGL 577
PG SG G K + S P + AG P +KG+P G +G G +GL
Sbjct: 848 PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGL 907
Score = 31.6 bits (70), Expect = 8.0
Identities = 18/59 (30%), Positives = 20/59 (33%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
PG G G T PK P G P +G P G AG G K +G
Sbjct: 641 PGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRG 699
>gi|164419758 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 40.8 bits (94), Expect = 0.013
Identities = 47/191 (24%), Positives = 80/191 (41%), Gaps = 36/191 (18%)
Query: 480 ADVDKLKLDKIKECSEKVELIHGKKAGLAA----------DKKEFKPLPGRTAASGAAG- 528
+D ++ + ++ E E++ +H + A L+ +KKE K G AG
Sbjct: 510 SDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGA 569
Query: 529 DKDTKDISAPKPG-PLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKGLETKEIVEPEL 587
D+D K AP+P P K A+ +GG P+ G +G +GTK K
Sbjct: 570 DEDDKGPRAPRPPQPKKSKKASGSGGGSAALGPSGFGPSGGSGTKLPK------------ 617
Query: 588 SIEVCEEKASAVLPPTCIQLLDSSNWKERLACMEEFQKAVELMDRTEMPCQALVRML--- 644
KA+ PP DS +E M +K +D ++P + L R++
Sbjct: 618 -------KATKTAPPALPTGYDSEE-EEESRPMSYDEKRQLSLDINKLPGEKLGRVVHII 669
Query: 645 -AKKPGWKETN 654
A++P +++N
Sbjct: 670 QAREPSLRDSN 680
>gi|4826806 bromodomain containing 2 [Homo sapiens]
Length = 801
Score = 40.8 bits (94), Expect = 0.013
Identities = 47/191 (24%), Positives = 80/191 (41%), Gaps = 36/191 (18%)
Query: 480 ADVDKLKLDKIKECSEKVELIHGKKAGLAA----------DKKEFKPLPGRTAASGAAG- 528
+D ++ + ++ E E++ +H + A L+ +KKE K G AG
Sbjct: 510 SDSEEERAHRLAELQEQLRAVHEQLAALSQGPISKPKRKREKKEKKKKRKAEKHRGRAGA 569
Query: 529 DKDTKDISAPKPG-PLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKGLETKEIVEPEL 587
D+D K AP+P P K A+ +GG P+ G +G +GTK K
Sbjct: 570 DEDDKGPRAPRPPQPKKSKKASGSGGGSAALGPSGFGPSGGSGTKLPK------------ 617
Query: 588 SIEVCEEKASAVLPPTCIQLLDSSNWKERLACMEEFQKAVELMDRTEMPCQALVRML--- 644
KA+ PP DS +E M +K +D ++P + L R++
Sbjct: 618 -------KATKTAPPALPTGYDSEE-EEESRPMSYDEKRQLSLDINKLPGEKLGRVVHII 669
Query: 645 -AKKPGWKETN 654
A++P +++N
Sbjct: 670 QAREPSLRDSN 680
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 40.4 bits (93), Expect = 0.017
Identities = 29/74 (39%), Positives = 33/74 (44%), Gaps = 11/74 (14%)
Query: 505 AGLAADKKEFKPL--PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAA 562
AG DK E P G T A GA GD+ +PGP PA AG P G+P A
Sbjct: 775 AGAPGDKGESGPSGPAGPTGARGAPGDRG-------EPGP--PGPAGFAGPPGADGQPGA 825
Query: 563 PGGAGNTGTKNKKG 576
G G+ G K G
Sbjct: 826 KGEPGDAGAKGDAG 839
Score = 37.0 bits (84), Expect = 0.19
Identities = 22/65 (33%), Positives = 28/65 (43%), Gaps = 6/65 (9%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAG--GPP----KKGKPAAPGGAGNTGT 571
PG GA G I+ P + P+ G GPP G+P APG G+TG
Sbjct: 388 PGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGA 447
Query: 572 KNKKG 576
K + G
Sbjct: 448 KGEPG 452
Score = 36.6 bits (83), Expect = 0.25
Identities = 20/59 (33%), Positives = 28/59 (47%), Gaps = 9/59 (15%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
PG+ SGA+G++ PGP+ P AG P + G+ APG G+ G G
Sbjct: 982 PGKQGPSGASGERGP-------PGPM--GPPGLAGPPGESGREGAPGAEGSPGRDGSPG 1031
Score = 35.8 bits (81), Expect = 0.43
Identities = 19/60 (31%), Positives = 26/60 (43%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKGL 577
PG +G G K + + P P + P G +KG P A G AG GT +G+
Sbjct: 895 PGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGI 954
Score = 33.9 bits (76), Expect = 1.6
Identities = 23/65 (35%), Positives = 27/65 (41%), Gaps = 6/65 (9%)
Query: 518 PGRTAASGAAGDKDTKDISAPK-----PGPLKKAPAA-KAGGPPKKGKPAAPGGAGNTGT 571
PG A G AG + + P+ PGP A AA AG P G+P A G G G
Sbjct: 346 PGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGI 405
Query: 572 KNKKG 576
G
Sbjct: 406 AGAPG 410
Score = 33.5 bits (75), Expect = 2.1
Identities = 22/74 (29%), Positives = 29/74 (39%), Gaps = 16/74 (21%)
Query: 517 LPGRTAASGAAGDKDTKDISAPK--------------PGPLKKAPAAKAGGPPKKGKPAA 562
+PG A+G G K + + PK GP+ P AG P KG+
Sbjct: 729 MPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPI--GPPGPAGAPGDKGESGP 786
Query: 563 PGGAGNTGTKNKKG 576
G AG TG + G
Sbjct: 787 SGPAGPTGARGAPG 800
Score = 33.1 bits (74), Expect = 2.8
Identities = 23/63 (36%), Positives = 26/63 (41%), Gaps = 5/63 (7%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPP----KKGKPAAPGGAGNTGTKN 573
PG GA G K + + P PG AA GPP G P PG AG G K
Sbjct: 850 PGPIGNVGAPGAKGARGSAGP-PGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKG 908
Query: 574 KKG 576
+G
Sbjct: 909 PRG 911
Score = 32.7 bits (73), Expect = 3.6
Identities = 25/68 (36%), Positives = 27/68 (39%), Gaps = 6/68 (8%)
Query: 515 KPLPGRTAASGAAGDKDTKDI--SAPKPGPLKKA----PAAKAGGPPKKGKPAAPGGAGN 568
K PG G AG K + S PGP K PA + G P G P A G AG
Sbjct: 520 KGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGV 579
Query: 569 TGTKNKKG 576
G KG
Sbjct: 580 MGFPGPKG 587
Score = 32.3 bits (72), Expect = 4.7
Identities = 24/74 (32%), Positives = 30/74 (40%), Gaps = 5/74 (6%)
Query: 505 AGLAADK--KEFKPLPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAA 562
AGL K + F L G +G AG K P + P G P ++G+P A
Sbjct: 259 AGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPR---GLPGERGRPGA 315
Query: 563 PGGAGNTGTKNKKG 576
PG AG G G
Sbjct: 316 PGPAGARGNDGATG 329
Score = 32.3 bits (72), Expect = 4.7
Identities = 21/74 (28%), Positives = 29/74 (39%), Gaps = 15/74 (20%)
Query: 518 PGRTAASGAAGDKDTKDISAP--------------KPGPLK-KAPAAKAGGPPKKGKPAA 562
PG +GA G+ + P +PGP P + GGP +G P A
Sbjct: 439 PGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGA 498
Query: 563 PGGAGNTGTKNKKG 576
G AG G ++G
Sbjct: 499 DGVAGPKGPAGERG 512
Score = 32.3 bits (72), Expect = 4.7
Identities = 20/63 (31%), Positives = 26/63 (41%), Gaps = 3/63 (4%)
Query: 514 FKPLPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKN 573
F L G G+ G++ S P GP + P AG P K G PG G G +
Sbjct: 1113 FSGLQGPPGPPGSPGEQGPSGASGPA-GP--RGPPGSAGAPGKDGLNGLPGPIGPPGPRG 1169
Query: 574 KKG 576
+ G
Sbjct: 1170 RTG 1172
Score = 32.0 bits (71), Expect = 6.1
Identities = 18/63 (28%), Positives = 25/63 (39%)
Query: 514 FKPLPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKN 573
F G G AG++ + + PK P + +AG P KG +PG G G
Sbjct: 495 FPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTG 554
Query: 574 KKG 576
G
Sbjct: 555 PPG 557
Score = 32.0 bits (71), Expect = 6.1
Identities = 28/77 (36%), Positives = 31/77 (40%), Gaps = 14/77 (18%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKK--APAAK-----AGGPPKKGKPAA------PG 564
PG A G AG + P PGP+ AP AK AG P G P A PG
Sbjct: 829 PGDAGAKGDAGPPGPAGPAGP-PGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPG 887
Query: 565 GAGNTGTKNKKGLETKE 581
+GN G G KE
Sbjct: 888 PSGNAGPPGPPGPAGKE 904
Score = 32.0 bits (71), Expect = 6.1
Identities = 18/59 (30%), Positives = 24/59 (40%), Gaps = 12/59 (20%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
PGR + GA GD+ + PA G P G P G AG +G + + G
Sbjct: 1024 PGRDGSPGAKGDRG------------ETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETG 1070
Score = 31.6 bits (70), Expect = 8.0
Identities = 18/60 (30%), Positives = 22/60 (36%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKGL 577
PG G G+ S P P K G + GKP PG G G + +GL
Sbjct: 196 PGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGL 255
Score = 31.6 bits (70), Expect = 8.0
Identities = 21/58 (36%), Positives = 24/58 (41%), Gaps = 6/58 (10%)
Query: 519 GRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
G+ A G GD K + P PGP A AG P G APG G G+ G
Sbjct: 821 GQPGAKGEPGDAGAKGDAGP-PGP-----AGPAGPPGPIGNVGAPGAKGARGSAGPPG 872
Score = 31.6 bits (70), Expect = 8.0
Identities = 23/71 (32%), Positives = 25/71 (35%), Gaps = 12/71 (16%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGG------------PPKKGKPAAPGG 565
PG T GAAG S P PA K GG P + G P PG
Sbjct: 871 PGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGP 930
Query: 566 AGNTGTKNKKG 576
AG G+ G
Sbjct: 931 AGEKGSPGADG 941
>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
sapiens]
Length = 1818
Score = 40.4 bits (93), Expect = 0.017
Identities = 26/62 (41%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAG--GPP-KKGKPAAPGGAGNTGTKNK 574
PG G GDK +D +PGP P+ +AG GPP K+G P A G G G K
Sbjct: 1335 PGPAGQDGVGGDKG-EDGDPGQPGP--PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGA 1391
Query: 575 KG 576
KG
Sbjct: 1392 KG 1393
Score = 37.0 bits (84), Expect = 0.19
Identities = 19/59 (32%), Positives = 25/59 (42%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
PG G++G K P+ + P G P K+G+P A GG G G KG
Sbjct: 552 PGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKG 610
Score = 35.8 bits (81), Expect = 0.43
Identities = 20/59 (33%), Positives = 26/59 (44%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
PG GAAG + K P+ K PA G P ++G P A G G G + +G
Sbjct: 1005 PGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQG 1063
Score = 32.7 bits (73), Expect = 3.6
Identities = 20/63 (31%), Positives = 26/63 (41%), Gaps = 3/63 (4%)
Query: 517 LPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGG---PPKKGKPAAPGGAGNTGTKN 573
LPG A G G + + P P ++ A AG P + G PG AG G
Sbjct: 1046 LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPG 1105
Query: 574 KKG 576
+KG
Sbjct: 1106 EKG 1108
Score = 32.7 bits (73), Expect = 3.6
Identities = 22/71 (30%), Positives = 31/71 (43%), Gaps = 7/71 (9%)
Query: 506 GLAADKKEFKPLPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGG 565
G+ DK E PG+ G +G+ + P P K+ P AG ++G+ A G
Sbjct: 1342 GVGGDKGEDGD-PGQPGPPGPSGE------AGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1394
Query: 566 AGNTGTKNKKG 576
AG G K G
Sbjct: 1395 AGAEGPPGKTG 1405
Score = 32.0 bits (71), Expect = 6.1
Identities = 23/69 (33%), Positives = 29/69 (42%), Gaps = 7/69 (10%)
Query: 517 LPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
LPGR G G + K P +K P AG +G PG AG G+ + G
Sbjct: 1085 LPGRPGPQGPPGP------AGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDG 1138
Query: 577 LETKEIVEP 585
+ EI EP
Sbjct: 1139 -DKGEIGEP 1146
Score = 31.6 bits (70), Expect = 8.0
Identities = 22/70 (31%), Positives = 26/70 (37%), Gaps = 12/70 (17%)
Query: 519 GRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAG-----------GPP-KKGKPAAPGGA 566
G +G G K T P P ++ P G GPP K G P PG
Sbjct: 904 GARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQR 963
Query: 567 GNTGTKNKKG 576
G TG + K G
Sbjct: 964 GETGFQGKTG 973
Score = 31.6 bits (70), Expect = 8.0
Identities = 26/72 (36%), Positives = 31/72 (43%), Gaps = 20/72 (27%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGP--LKKAP----------AAKAGGPP-KKGKPAAPG 564
PG+T G G A KPGP L+ P AA GPP G P PG
Sbjct: 1401 PGKTGPVGPQGP-------AGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPG 1453
Query: 565 GAGNTGTKNKKG 576
G+ G+K +KG
Sbjct: 1454 LKGDPGSKGEKG 1465
>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
sapiens]
Length = 1767
Score = 40.4 bits (93), Expect = 0.017
Identities = 26/62 (41%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAG--GPP-KKGKPAAPGGAGNTGTKNK 574
PG G GDK +D +PGP P+ +AG GPP K+G P A G G G K
Sbjct: 1284 PGPAGQDGVGGDKG-EDGDPGQPGP--PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGA 1340
Query: 575 KG 576
KG
Sbjct: 1341 KG 1342
Score = 37.0 bits (84), Expect = 0.19
Identities = 19/59 (32%), Positives = 25/59 (42%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
PG G++G K P+ + P G P K+G+P A GG G G KG
Sbjct: 501 PGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKG 559
Score = 35.8 bits (81), Expect = 0.43
Identities = 20/59 (33%), Positives = 26/59 (44%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
PG GAAG + K P+ K PA G P ++G P A G G G + +G
Sbjct: 954 PGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQG 1012
Score = 32.7 bits (73), Expect = 3.6
Identities = 20/63 (31%), Positives = 26/63 (41%), Gaps = 3/63 (4%)
Query: 517 LPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGG---PPKKGKPAAPGGAGNTGTKN 573
LPG A G G + + P P ++ A AG P + G PG AG G
Sbjct: 995 LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPG 1054
Query: 574 KKG 576
+KG
Sbjct: 1055 EKG 1057
Score = 32.7 bits (73), Expect = 3.6
Identities = 22/71 (30%), Positives = 31/71 (43%), Gaps = 7/71 (9%)
Query: 506 GLAADKKEFKPLPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGG 565
G+ DK E PG+ G +G+ + P P K+ P AG ++G+ A G
Sbjct: 1291 GVGGDKGEDGD-PGQPGPPGPSGE------AGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1343
Query: 566 AGNTGTKNKKG 576
AG G K G
Sbjct: 1344 AGAEGPPGKTG 1354
Score = 32.0 bits (71), Expect = 6.1
Identities = 23/69 (33%), Positives = 29/69 (42%), Gaps = 7/69 (10%)
Query: 517 LPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
LPGR G G + K P +K P AG +G PG AG G+ + G
Sbjct: 1034 LPGRPGPQGPPGP------AGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDG 1087
Query: 577 LETKEIVEP 585
+ EI EP
Sbjct: 1088 -DKGEIGEP 1095
Score = 31.6 bits (70), Expect = 8.0
Identities = 22/70 (31%), Positives = 26/70 (37%), Gaps = 12/70 (17%)
Query: 519 GRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAG-----------GPP-KKGKPAAPGGA 566
G +G G K T P P ++ P G GPP K G P PG
Sbjct: 853 GARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQR 912
Query: 567 GNTGTKNKKG 576
G TG + K G
Sbjct: 913 GETGFQGKTG 922
Score = 31.6 bits (70), Expect = 8.0
Identities = 26/72 (36%), Positives = 31/72 (43%), Gaps = 20/72 (27%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGP--LKKAP----------AAKAGGPP-KKGKPAAPG 564
PG+T G G A KPGP L+ P AA GPP G P PG
Sbjct: 1350 PGKTGPVGPQGP-------AGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPG 1402
Query: 565 GAGNTGTKNKKG 576
G+ G+K +KG
Sbjct: 1403 LKGDPGSKGEKG 1414
>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
sapiens]
Length = 1806
Score = 40.4 bits (93), Expect = 0.017
Identities = 26/62 (41%), Positives = 31/62 (50%), Gaps = 6/62 (9%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAG--GPP-KKGKPAAPGGAGNTGTKNK 574
PG G GDK +D +PGP P+ +AG GPP K+G P A G G G K
Sbjct: 1323 PGPAGQDGVGGDKG-EDGDPGQPGP--PGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGA 1379
Query: 575 KG 576
KG
Sbjct: 1380 KG 1381
Score = 37.0 bits (84), Expect = 0.19
Identities = 19/59 (32%), Positives = 25/59 (42%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
PG G++G K P+ + P G P K+G+P A GG G G KG
Sbjct: 540 PGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKG 598
Score = 35.8 bits (81), Expect = 0.43
Identities = 20/59 (33%), Positives = 26/59 (44%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
PG GAAG + K P+ K PA G P ++G P A G G G + +G
Sbjct: 993 PGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQG 1051
Score = 32.7 bits (73), Expect = 3.6
Identities = 20/63 (31%), Positives = 26/63 (41%), Gaps = 3/63 (4%)
Query: 517 LPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGG---PPKKGKPAAPGGAGNTGTKN 573
LPG A G G + + P P ++ A AG P + G PG AG G
Sbjct: 1034 LPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPG 1093
Query: 574 KKG 576
+KG
Sbjct: 1094 EKG 1096
Score = 32.7 bits (73), Expect = 3.6
Identities = 22/71 (30%), Positives = 31/71 (43%), Gaps = 7/71 (9%)
Query: 506 GLAADKKEFKPLPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGG 565
G+ DK E PG+ G +G+ + P P K+ P AG ++G+ A G
Sbjct: 1330 GVGGDKGEDGD-PGQPGPPGPSGE------AGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1382
Query: 566 AGNTGTKNKKG 576
AG G K G
Sbjct: 1383 AGAEGPPGKTG 1393
Score = 32.0 bits (71), Expect = 6.1
Identities = 23/69 (33%), Positives = 29/69 (42%), Gaps = 7/69 (10%)
Query: 517 LPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNKKG 576
LPGR G G + K P +K P AG +G PG AG G+ + G
Sbjct: 1073 LPGRPGPQGPPGP------AGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDG 1126
Query: 577 LETKEIVEP 585
+ EI EP
Sbjct: 1127 -DKGEIGEP 1134
Score = 31.6 bits (70), Expect = 8.0
Identities = 22/70 (31%), Positives = 26/70 (37%), Gaps = 12/70 (17%)
Query: 519 GRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAG-----------GPP-KKGKPAAPGGA 566
G +G G K T P P ++ P G GPP K G P PG
Sbjct: 892 GARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQR 951
Query: 567 GNTGTKNKKG 576
G TG + K G
Sbjct: 952 GETGFQGKTG 961
Score = 31.6 bits (70), Expect = 8.0
Identities = 26/72 (36%), Positives = 31/72 (43%), Gaps = 20/72 (27%)
Query: 518 PGRTAASGAAGDKDTKDISAPKPGP--LKKAP----------AAKAGGPP-KKGKPAAPG 564
PG+T G G A KPGP L+ P AA GPP G P PG
Sbjct: 1389 PGKTGPVGPQGP-------AGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPG 1441
Query: 565 GAGNTGTKNKKG 576
G+ G+K +KG
Sbjct: 1442 LKGDPGSKGEKG 1453
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 40.0 bits (92), Expect = 0.023
Identities = 42/121 (34%), Positives = 54/121 (44%), Gaps = 15/121 (12%)
Query: 1055 AKATGKLKPTSKDQVLAMLEKAKVNMPAKPAPPTKATSKPMGGSAPAKFQPASAPAEDCI 1114
AKA+GK TS+ + K A PAPP K G A AK Q A ED
Sbjct: 285 AKASGK---TSQVGAASAPAKESPRKGAAPAPPGKT------GPAVAKAQ-AGKREEDSQ 334
Query: 1115 SSSTEPKPD---PKKAKAPGLSS--KAKSAQGKKMPSKTSLKEDEDKSGPIFIVVPNGKE 1169
SSS E + P +AK G + +A SA K+ P K + K+GP V GK+
Sbjct: 335 SSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQ 394
Query: 1170 Q 1170
+
Sbjct: 395 E 395
Score = 38.9 bits (89), Expect = 0.050
Identities = 35/111 (31%), Positives = 46/111 (41%), Gaps = 12/111 (10%)
Query: 1072 MLEKAKVNMPAKPAPPTKATSKPMG-GSAPAKFQPASAPAEDCISSSTEPKPDPK----- 1125
+L+ + PAK P AT P G A A A P ED SSS E +
Sbjct: 220 ILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAA 279
Query: 1126 ----KAKAPGLSSK--AKSAQGKKMPSKTSLKEDEDKSGPIFIVVPNGKEQ 1170
+AKA G +S+ A SA K+ P K + K+GP GK +
Sbjct: 280 KALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKRE 330
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 40.0 bits (92), Expect = 0.023
Identities = 42/121 (34%), Positives = 54/121 (44%), Gaps = 15/121 (12%)
Query: 1055 AKATGKLKPTSKDQVLAMLEKAKVNMPAKPAPPTKATSKPMGGSAPAKFQPASAPAEDCI 1114
AKA+GK TS+ + K A PAPP K G A AK Q A ED
Sbjct: 362 AKASGK---TSQVGAASAPAKESPRKGAAPAPPGKT------GPAVAKAQ-AGKREEDSQ 411
Query: 1115 SSSTEPKPD---PKKAKAPGLSS--KAKSAQGKKMPSKTSLKEDEDKSGPIFIVVPNGKE 1169
SSS E + P +AK G + +A SA K+ P K + K+GP V GK+
Sbjct: 412 SSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQ 471
Query: 1170 Q 1170
+
Sbjct: 472 E 472
Score = 38.9 bits (89), Expect = 0.050
Identities = 35/111 (31%), Positives = 46/111 (41%), Gaps = 12/111 (10%)
Query: 1072 MLEKAKVNMPAKPAPPTKATSKPMG-GSAPAKFQPASAPAEDCISSSTEPKPDPK----- 1125
+L+ + PAK P AT P G A A A P ED SSS E +
Sbjct: 297 ILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAA 356
Query: 1126 ----KAKAPGLSSK--AKSAQGKKMPSKTSLKEDEDKSGPIFIVVPNGKEQ 1170
+AKA G +S+ A SA K+ P K + K+GP GK +
Sbjct: 357 KALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKRE 407
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 40.0 bits (92), Expect = 0.023
Identities = 42/121 (34%), Positives = 54/121 (44%), Gaps = 15/121 (12%)
Query: 1055 AKATGKLKPTSKDQVLAMLEKAKVNMPAKPAPPTKATSKPMGGSAPAKFQPASAPAEDCI 1114
AKA+GK TS+ + K A PAPP K G A AK Q A ED
Sbjct: 362 AKASGK---TSQVGAASAPAKESPRKGAAPAPPGKT------GPAVAKAQ-AGKREEDSQ 411
Query: 1115 SSSTEPKPD---PKKAKAPGLSS--KAKSAQGKKMPSKTSLKEDEDKSGPIFIVVPNGKE 1169
SSS E + P +AK G + +A SA K+ P K + K+GP V GK+
Sbjct: 412 SSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQ 471
Query: 1170 Q 1170
+
Sbjct: 472 E 472
Score = 38.9 bits (89), Expect = 0.050
Identities = 35/111 (31%), Positives = 46/111 (41%), Gaps = 12/111 (10%)
Query: 1072 MLEKAKVNMPAKPAPPTKATSKPMG-GSAPAKFQPASAPAEDCISSSTEPKPDPK----- 1125
+L+ + PAK P AT P G A A A P ED SSS E +
Sbjct: 297 ILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAA 356
Query: 1126 ----KAKAPGLSSK--AKSAQGKKMPSKTSLKEDEDKSGPIFIVVPNGKEQ 1170
+AKA G +S+ A SA K+ P K + K+GP GK +
Sbjct: 357 KALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKRE 407
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo
sapiens]
Length = 1411
Score = 40.0 bits (92), Expect = 0.023
Identities = 42/121 (34%), Positives = 54/121 (44%), Gaps = 15/121 (12%)
Query: 1055 AKATGKLKPTSKDQVLAMLEKAKVNMPAKPAPPTKATSKPMGGSAPAKFQPASAPAEDCI 1114
AKA+GK TS+ + K A PAPP K G A AK Q A ED
Sbjct: 285 AKASGK---TSQVGAASAPAKESPRKGAAPAPPGKT------GPAVAKAQ-AGKREEDSQ 334
Query: 1115 SSSTEPKPD---PKKAKAPGLSS--KAKSAQGKKMPSKTSLKEDEDKSGPIFIVVPNGKE 1169
SSS E + P +AK G + +A SA K+ P K + K+GP V GK+
Sbjct: 335 SSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQ 394
Query: 1170 Q 1170
+
Sbjct: 395 E 395
Score = 38.9 bits (89), Expect = 0.050
Identities = 35/111 (31%), Positives = 46/111 (41%), Gaps = 12/111 (10%)
Query: 1072 MLEKAKVNMPAKPAPPTKATSKPMG-GSAPAKFQPASAPAEDCISSSTEPKPDPK----- 1125
+L+ + PAK P AT P G A A A P ED SSS E +
Sbjct: 220 ILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAA 279
Query: 1126 ----KAKAPGLSSK--AKSAQGKKMPSKTSLKEDEDKSGPIFIVVPNGKEQ 1170
+AKA G +S+ A SA K+ P K + K+GP GK +
Sbjct: 280 KALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKRE 330
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo
sapiens]
Length = 1450
Score = 40.0 bits (92), Expect = 0.023
Identities = 42/121 (34%), Positives = 54/121 (44%), Gaps = 15/121 (12%)
Query: 1055 AKATGKLKPTSKDQVLAMLEKAKVNMPAKPAPPTKATSKPMGGSAPAKFQPASAPAEDCI 1114
AKA+GK TS+ + K A PAPP K G A AK Q A ED
Sbjct: 362 AKASGK---TSQVGAASAPAKESPRKGAAPAPPGKT------GPAVAKAQ-AGKREEDSQ 411
Query: 1115 SSSTEPKPD---PKKAKAPGLSS--KAKSAQGKKMPSKTSLKEDEDKSGPIFIVVPNGKE 1169
SSS E + P +AK G + +A SA K+ P K + K+GP V GK+
Sbjct: 412 SSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQ 471
Query: 1170 Q 1170
+
Sbjct: 472 E 472
Score = 38.9 bits (89), Expect = 0.050
Identities = 35/111 (31%), Positives = 46/111 (41%), Gaps = 12/111 (10%)
Query: 1072 MLEKAKVNMPAKPAPPTKATSKPMG-GSAPAKFQPASAPAEDCISSSTEPKPDPK----- 1125
+L+ + PAK P AT P G A A A P ED SSS E +
Sbjct: 297 ILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAA 356
Query: 1126 ----KAKAPGLSSK--AKSAQGKKMPSKTSLKEDEDKSGPIFIVVPNGKEQ 1170
+AKA G +S+ A SA K+ P K + K+GP GK +
Sbjct: 357 KALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKRE 407
>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c [Homo
sapiens]
Length = 958
Score = 40.0 bits (92), Expect = 0.023
Identities = 42/121 (34%), Positives = 54/121 (44%), Gaps = 15/121 (12%)
Query: 1055 AKATGKLKPTSKDQVLAMLEKAKVNMPAKPAPPTKATSKPMGGSAPAKFQPASAPAEDCI 1114
AKA+GK TS+ + K A PAPP K G A AK Q A ED
Sbjct: 362 AKASGK---TSQVGAASAPAKESPRKGAAPAPPGKT------GPAVAKAQ-AGKREEDSQ 411
Query: 1115 SSSTEPKPD---PKKAKAPGLSS--KAKSAQGKKMPSKTSLKEDEDKSGPIFIVVPNGKE 1169
SSS E + P +AK G + +A SA K+ P K + K+GP V GK+
Sbjct: 412 SSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQ 471
Query: 1170 Q 1170
+
Sbjct: 472 E 472
Score = 38.9 bits (89), Expect = 0.050
Identities = 35/111 (31%), Positives = 46/111 (41%), Gaps = 12/111 (10%)
Query: 1072 MLEKAKVNMPAKPAPPTKATSKPMG-GSAPAKFQPASAPAEDCISSSTEPKPDPK----- 1125
+L+ + PAK P AT P G A A A P ED SSS E +
Sbjct: 297 ILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAA 356
Query: 1126 ----KAKAPGLSSK--AKSAQGKKMPSKTSLKEDEDKSGPIFIVVPNGKEQ 1170
+AKA G +S+ A SA K+ P K + K+GP GK +
Sbjct: 357 KALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKRE 407
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 39.7 bits (91), Expect = 0.029
Identities = 40/139 (28%), Positives = 58/139 (41%), Gaps = 22/139 (15%)
Query: 1055 AKATGKLKPTSKDQVLAMLE-----KAKVNMPAKPAPPTKATSKPMGGSAPAKFQPASAP 1109
AK+ K K K++ + E K + PA+ P KA S P K + A +P
Sbjct: 598 AKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKS-------PTK-EEAKSP 649
Query: 1110 AEDCISSSTEPKPDPKKAKAPGLSSKAKSAQGKKMPSKTSLKEDEDKSGPIFIVVPNGKE 1169
E S E P+KAK+P + ++AKS + K P K K E P+ KE
Sbjct: 650 -EKAKSPEKEEAKSPEKAKSP-VKAEAKSPEKAKSPVKAEAKSPEKAKSPV-------KE 700
Query: 1170 QRMKDEKGLKVLKWNFTTP 1188
+ EK +K +P
Sbjct: 701 EAKSPEKAKSPVKEEAKSP 719
Score = 39.3 bits (90), Expect = 0.038
Identities = 33/111 (29%), Positives = 49/111 (44%), Gaps = 11/111 (9%)
Query: 1056 KATGKLKPTSKDQVLAMLEKAKVNMPAKPAPPTKATSK-PMGGSAPAKFQPASAPAE--- 1111
K+ K K +K++ + A+ P K P K +K P +P K + A +PAE
Sbjct: 579 KSPEKAKSPAKEEAKS---PAEAKSPEKAKSPVKEEAKSPAEAKSPVK-EEAKSPAEVKS 634
Query: 1112 --DCISSSTEPKPDPKKAKAPGLSSKAKSAQGKKMPSKTSLKEDEDKSGPI 1160
S + E P+KAK+P +AKS + K P K K E P+
Sbjct: 635 PEKAKSPTKEEAKSPEKAKSPE-KEEAKSPEKAKSPVKAEAKSPEKAKSPV 684
Score = 36.6 bits (83), Expect = 0.25
Identities = 32/108 (29%), Positives = 52/108 (48%), Gaps = 11/108 (10%)
Query: 1055 AKATGKLKPTSKDQVLAMLEKAKVNMPAKPAPPTKATSK-PMGGSAPAKFQPASAPAEDC 1113
AK+ + K K++ + A+V P K P K +K P +P K + A +PAE
Sbjct: 524 AKSPAEAKSPEKEEAKS---PAEVKSPEKAKSPAKEEAKSPPEAKSPEK-EEAKSPAE-- 577
Query: 1114 ISSSTEPK-PDPKKAKAPGLSSKAKSAQGKKMPSKTSLKEDEDKSGPI 1160
+ S + K P ++AK+P ++AKS + K P K K + P+
Sbjct: 578 VKSPEKAKSPAKEEAKSP---AEAKSPEKAKSPVKEEAKSPAEAKSPV 622
Score = 35.8 bits (81), Expect = 0.43
Identities = 41/139 (29%), Positives = 54/139 (38%), Gaps = 20/139 (14%)
Query: 1055 AKATGKLKPTSKDQVLAMLEKAKVNMPAKPAPPTKATSKPMGGSAPAKFQPASAPAE--- 1111
AK K P +K EK + PA+ P KA S PAK + A +PAE
Sbjct: 554 AKEEAKSPPEAKSP-----EKEEAKSPAEVKSPEKAKS-------PAK-EEAKSPAEAKS 600
Query: 1112 --DCISSSTEPKPDPKKAKAPGLSSKAKSAQGKKMPSKTSLKEDEDKSGPIFIVVPNGKE 1169
S E P +AK+P + +AKS K P K E+ P P KE
Sbjct: 601 PEKAKSPVKEEAKSPAEAKSP-VKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPE-KE 658
Query: 1170 QRMKDEKGLKVLKWNFTTP 1188
+ EK +K +P
Sbjct: 659 EAKSPEKAKSPVKAEAKSP 677
Score = 35.8 bits (81), Expect = 0.43
Identities = 36/134 (26%), Positives = 59/134 (44%), Gaps = 18/134 (13%)
Query: 1055 AKATGKLKPTSKDQVLAMLEKAKVNMPAKPAPPTKATSKPMGGSAPAKFQPASAPAEDCI 1114
AK+ K K K++ EKAK + + P KA S + K A PA++
Sbjct: 716 AKSPEKAKSPVKEEAKTP-EKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEA 774
Query: 1115 SSSTEPKPD------------PKKAKAPGLSSKAKSAQGKKMPSKTSLK---EDEDKSGP 1159
S + P+ P+KAK+P L AK+ + K++P K +K ++E+K
Sbjct: 775 RSPADKFPEKAKSPVKEEVKSPEKAKSP-LKEDAKAPE-KEIPKKEEVKSPVKEEEKPQE 832
Query: 1160 IFIVVPNGKEQRMK 1173
+ + P K + K
Sbjct: 833 VKVKEPPKKAEEEK 846
Score = 35.0 bits (79), Expect = 0.73
Identities = 41/139 (29%), Positives = 53/139 (38%), Gaps = 13/139 (9%)
Query: 1056 KATGKLKPTSKDQVLAMLEKAKVNMPAKPAPPTKATSK-PMGGSAPAKFQPASAPAEDCI 1114
KA K +K V K + P K P K +K P +P K + A P E
Sbjct: 685 KAEAKSPEKAKSPV-----KEEAKSPEKAKSPVKEEAKSPEKAKSPVK-EEAKTP-EKAK 737
Query: 1115 SSSTEPKPDPKKAKAPGLSSKAKSAQGKKMPSKTSLKEDEDKSGPIFIVVPNG--KEQRM 1172
S E P+KAK+P KAK+ K +KT KE+ F KE+
Sbjct: 738 SPVKEEAKSPEKAKSP---EKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVK 794
Query: 1173 KDEKGLKVLKWNFTTPRDE 1191
EK LK + P E
Sbjct: 795 SPEKAKSPLKEDAKAPEKE 813
Score = 32.7 bits (73), Expect = 3.6
Identities = 34/123 (27%), Positives = 52/123 (42%), Gaps = 9/123 (7%)
Query: 1075 KAKVNMPAKPAPPTKATSKPMGGSAPAKFQPASAPAEDCISSSTEPKPDPKKA---KAPG 1131
K +V P K P K +K P K + S E+ + K PKKA KAP
Sbjct: 790 KEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPA 849
Query: 1132 L--SSKAKSAQGKKMPSKTSLK-EDEDKSGPIFIVVPNGKEQRMKDEKGLKVLKWNFTTP 1188
+ + K ++ ++ P K + K + E+K P V KE +++ +K K TP
Sbjct: 850 TPKTEEKKDSKKEEAPKKEAPKPKVEEKKEP---AVEKPKESKVEAKKEEAEDKKKVPTP 906
Query: 1189 RDE 1191
E
Sbjct: 907 EKE 909
Score = 32.7 bits (73), Expect = 3.6
Identities = 24/88 (27%), Positives = 36/88 (40%), Gaps = 3/88 (3%)
Query: 1055 AKATGKLKPTSKDQVLAMLEKAKVNMPAKPAPPTKATSKPMGGSAPAKFQPASAPAEDCI 1114
AKA KP K + + K KP K +K +P+ AE
Sbjct: 936 AKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAE 995
Query: 1115 SSSTEPKPDPKKAKAPGLSSKAKSAQGK 1142
SS+ D K +K P +++ K+A+GK
Sbjct: 996 KSSS---TDQKDSKPPEKATEDKAAKGK 1020
Score = 32.3 bits (72), Expect = 4.7
Identities = 26/87 (29%), Positives = 42/87 (48%), Gaps = 8/87 (9%)
Query: 1074 EKAKVNMPAKPAPPTKATSKPMGGSAPAKFQPASAPAEDCISSSTEPK-PDPKKAKAPGL 1132
E+AK AK +P + P +P K A +PA++ S E K P+ ++AK+P
Sbjct: 522 EEAKSPAEAK-SPEKEEAKSPAEVKSPEK---AKSPAKEEAKSPPEAKSPEKEEAKSP-- 575
Query: 1133 SSKAKSAQGKKMPSKTSLKEDEDKSGP 1159
++ KS + K P+K K + P
Sbjct: 576 -AEVKSPEKAKSPAKEEAKSPAEAKSP 601
>gi|187829730 BCL2 binding component 3 isoform 1 [Homo sapiens]
Length = 261
Score = 38.5 bits (88), Expect = 0.066
Identities = 24/92 (26%), Positives = 39/92 (42%), Gaps = 9/92 (9%)
Query: 515 KPLPGRTAASGAAGDKDTKDISAPKPGPLKKAPAAKAGGPPKKGKPAAPGGAGNTGTKNK 574
+P PGR++A AG A +PG +GG G P +P G G G
Sbjct: 121 RPAPGRSSALALAGGAAPGVARAQRPGG--------SGGRSHPGGPGSPRGGGTVG-PGD 171
Query: 575 KGLETKEIVEPELSIEVCEEKASAVLPPTCIQ 606
+G + P+ ++ E + +A PP ++
Sbjct: 172 RGPAAADGGRPQRTVRAAETRGAAAAPPLTLE 203
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.131 0.368
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 73,492,347
Number of Sequences: 37866
Number of extensions: 3464803
Number of successful extensions: 19650
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 92
Number of HSP's successfully gapped in prelim test: 190
Number of HSP's that attempted gapping in prelim test: 14330
Number of HSP's gapped (non-prelim): 5074
length of query: 1972
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1855
effective length of database: 13,817,196
effective search space: 25630898580
effective search space used: 25630898580
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.