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Search of human proteins with 55770876
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|55770876 notch4 preproprotein [Homo sapiens]
(2003 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|55770876 notch4 preproprotein [Homo sapiens] 4460 0.0
gi|148833508 notch1 preproprotein [Homo sapiens] 1382 0.0
gi|134244285 Notch homolog 3 [Homo sapiens] 1334 0.0
gi|24041035 notch 2 preproprotein [Homo sapiens] 1294 0.0
gi|224451128 eyes shut homolog isoform 1 [Homo sapiens] 501 e-141
gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 462 e-129
gi|4557679 jagged 1 precursor [Homo sapiens] 449 e-125
gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 437 e-122
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 419 e-116
gi|122937283 6720455I24Rik homolog [Homo sapiens] 384 e-106
gi|41327708 crumbs homolog 1 precursor [Homo sapiens] 354 5e-97
gi|56237021 fibrillin 3 precursor [Homo sapiens] 353 9e-97
gi|24430141 fibrillin 1 precursor [Homo sapiens] 337 9e-92
gi|66346695 fibrillin 2 precursor [Homo sapiens] 327 9e-89
gi|112420992 crumbs homolog 2 [Homo sapiens] 325 3e-88
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 285 3e-76
gi|110347437 latent transforming growth factor beta binding prot... 268 4e-71
gi|110347412 latent transforming growth factor beta binding prot... 268 4e-71
gi|110347431 latent transforming growth factor beta binding prot... 268 4e-71
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 257 7e-68
gi|116235485 delta-notch-like EGF repeat-containing transmembran... 248 4e-65
gi|4557733 latent transforming growth factor beta binding protei... 247 9e-65
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 247 9e-65
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 240 9e-63
gi|148886654 polydom [Homo sapiens] 237 1e-61
gi|9506545 delta-like 4 protein precursor [Homo sapiens] 236 2e-61
gi|110735443 delta-like 1 [Homo sapiens] 230 1e-59
gi|194328809 latent transforming growth factor beta binding prot... 217 8e-56
gi|18497288 latent transforming growth factor beta binding prote... 202 3e-51
gi|188528675 slit homolog 1 [Homo sapiens] 201 5e-51
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 4460 bits (11568), Expect = 0.0
Identities = 2003/2003 (100%), Positives = 2003/2003 (100%)
Query: 1 MQPPSLLLLLLLLLLLCVSVVRPRGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGE 60
MQPPSLLLLLLLLLLLCVSVVRPRGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGE
Sbjct: 1 MQPPSLLLLLLLLLLLCVSVVRPRGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGE 60
Query: 61 TCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLED 120
TCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLED
Sbjct: 61 TCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLED 120
Query: 121 PCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQC 180
PCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQC
Sbjct: 121 PCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQC 180
Query: 181 HCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPP 240
HCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPP
Sbjct: 181 HCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPP 240
Query: 241 RGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTC 300
RGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTC
Sbjct: 241 RGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTC 300
Query: 301 LCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCI 360
LCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCI
Sbjct: 301 LCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCI 360
Query: 361 AATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLC 420
AATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLC
Sbjct: 361 AATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLC 420
Query: 421 QPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECL 480
QPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECL
Sbjct: 421 QPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECL 480
Query: 481 SQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICL 540
SQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICL
Sbjct: 481 SQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICL 540
Query: 541 PGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPV 600
PGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPV
Sbjct: 541 PGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPV 600
Query: 601 GASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAP 660
GASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAP
Sbjct: 601 GASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAP 660
Query: 661 PEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTG 720
PEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTG
Sbjct: 661 PEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTG 720
Query: 721 YTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGG 780
YTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGG
Sbjct: 721 YTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGG 780
Query: 781 TCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGS 840
TCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGS
Sbjct: 781 TCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGS 840
Query: 841 CQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL 900
CQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL
Sbjct: 841 CQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSL 900
Query: 901 CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGY 960
CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGY
Sbjct: 901 CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGY 960
Query: 961 DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGT 1020
DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGT
Sbjct: 961 DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGT 1020
Query: 1021 AACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFE 1080
AACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFE
Sbjct: 1021 AACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFE 1080
Query: 1081 GPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPC 1140
GPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPC
Sbjct: 1081 GPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPC 1140
Query: 1141 LYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWDG 1200
LYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWDG
Sbjct: 1141 LYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWDG 1200
Query: 1201 GDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCETPPACTPAYDQYCH 1260
GDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCETPPACTPAYDQYCH
Sbjct: 1201 GDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCETPPACTPAYDQYCH 1260
Query: 1261 DHFHNGHCEKGCNTAECGWDGGDCRPEDGDPEWGPSLALLVVLSPPALDQQLFALARVLS 1320
DHFHNGHCEKGCNTAECGWDGGDCRPEDGDPEWGPSLALLVVLSPPALDQQLFALARVLS
Sbjct: 1261 DHFHNGHCEKGCNTAECGWDGGDCRPEDGDPEWGPSLALLVVLSPPALDQQLFALARVLS 1320
Query: 1321 LTLRVGLWVRKDRDGRDMVYPYPGARAEEKLGGTRDPTYQERAAPQTQPLGKETDSLSAG 1380
LTLRVGLWVRKDRDGRDMVYPYPGARAEEKLGGTRDPTYQERAAPQTQPLGKETDSLSAG
Sbjct: 1321 LTLRVGLWVRKDRDGRDMVYPYPGARAEEKLGGTRDPTYQERAAPQTQPLGKETDSLSAG 1380
Query: 1381 FVVVMGVDLSRCGPDHPASRCPWDPGLLLRFLAAMAAVGALEPLLPGPLLAVHPHAGTAP 1440
FVVVMGVDLSRCGPDHPASRCPWDPGLLLRFLAAMAAVGALEPLLPGPLLAVHPHAGTAP
Sbjct: 1381 FVVVMGVDLSRCGPDHPASRCPWDPGLLLRFLAAMAAVGALEPLLPGPLLAVHPHAGTAP 1440
Query: 1441 PANQLPWPVLCSPVAGVILLALGALLVLQLIRRRRREHGALWLPPGFTRRPRTQSAPHRR 1500
PANQLPWPVLCSPVAGVILLALGALLVLQLIRRRRREHGALWLPPGFTRRPRTQSAPHRR
Sbjct: 1441 PANQLPWPVLCSPVAGVILLALGALLVLQLIRRRRREHGALWLPPGFTRRPRTQSAPHRR 1500
Query: 1501 RPPLGEDSIGLKALKPKAEVDEDGVVMCSGPEEGEEVGQAEETGPPSTCQLWSLSGGCGA 1560
RPPLGEDSIGLKALKPKAEVDEDGVVMCSGPEEGEEVGQAEETGPPSTCQLWSLSGGCGA
Sbjct: 1501 RPPLGEDSIGLKALKPKAEVDEDGVVMCSGPEEGEEVGQAEETGPPSTCQLWSLSGGCGA 1560
Query: 1561 LPQAAMLTPPQESEMEAPDLDTRGPDGVTPLMSAVCCGEVQSGTFQGAWLGCPEPWEPLL 1620
LPQAAMLTPPQESEMEAPDLDTRGPDGVTPLMSAVCCGEVQSGTFQGAWLGCPEPWEPLL
Sbjct: 1561 LPQAAMLTPPQESEMEAPDLDTRGPDGVTPLMSAVCCGEVQSGTFQGAWLGCPEPWEPLL 1620
Query: 1621 DGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAR 1680
DGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAR
Sbjct: 1621 DGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAR 1680
Query: 1681 EVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHW 1740
EVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHW
Sbjct: 1681 EVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHW 1740
Query: 1741 AAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAG 1800
AAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAG
Sbjct: 1741 AAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAG 1800
Query: 1801 LAPADVAHQRNHWDLLTLLEGAGPPEARHKATPGREAGPFPRARTVSVSVPPHGGGALPR 1860
LAPADVAHQRNHWDLLTLLEGAGPPEARHKATPGREAGPFPRARTVSVSVPPHGGGALPR
Sbjct: 1801 LAPADVAHQRNHWDLLTLLEGAGPPEARHKATPGREAGPFPRARTVSVSVPPHGGGALPR 1860
Query: 1861 CRTLSAGAGPRGGGACLQARTWSVDLAARGGGAYSHCRSLSGVGAGGGPTPRGRRFSAGM 1920
CRTLSAGAGPRGGGACLQARTWSVDLAARGGGAYSHCRSLSGVGAGGGPTPRGRRFSAGM
Sbjct: 1861 CRTLSAGAGPRGGGACLQARTWSVDLAARGGGAYSHCRSLSGVGAGGGPTPRGRRFSAGM 1920
Query: 1921 RGPRPNPAIMRGRYGVAAGRGGRVSTDDWPCDWVALGACGSASNIPIPPPCLTPSPERGS 1980
RGPRPNPAIMRGRYGVAAGRGGRVSTDDWPCDWVALGACGSASNIPIPPPCLTPSPERGS
Sbjct: 1921 RGPRPNPAIMRGRYGVAAGRGGRVSTDDWPCDWVALGACGSASNIPIPPPCLTPSPERGS 1980
Query: 1981 PQLDCGPPALQEMPINQGGEGKK 2003
PQLDCGPPALQEMPINQGGEGKK
Sbjct: 1981 PQLDCGPPALQEMPINQGGEGKK 2003
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 1382 bits (3576), Expect = 0.0
Identities = 760/1935 (39%), Positives = 999/1935 (51%), Gaps = 190/1935 (9%)
Query: 32 PEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQ--------- 81
P PC NGGTC C C PGF G+ C+ D C C+NGG+C
Sbjct: 224 PSPCQNGGTCRPTGDVTHECACLPGFTGQNCEENIDDCPGNN-CKNGGACVDGVNTYNCR 282
Query: 82 -----------------ALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPP 124
L+P + + C C+ G+TGE C ++D C
Sbjct: 283 CPPEWTGQYCTEDVDECQLMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDD-CAS 341
Query: 125 SFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYP---QIQCH 181
+ C CH + + C C G TG C L D C +NPC G C T P + C
Sbjct: 342 AACFHGATCHDRVASF-YCECPHGRTGLLCHLNDACISNPCNEGSNC-DTNPVNGKAICT 399
Query: 182 CPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPR 241
CP G+ G AC +DV+EC PC C NTLGSF+C C G GPRCE+ C
Sbjct: 400 CPSGYTGPACSQDVDECSLGANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSN 459
Query: 242 GCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCL 301
C N TC ++ F C+C PG+ G CEVN D C S C + G C D ++ + C
Sbjct: 460 PCQNDATCL---DQIGEFQ-CICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCE 515
Query: 302 CPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIA 361
CP +TG C DVDEC + C+NG C + ++ CVC G+ GT CE ++D+C
Sbjct: 516 CPTGFTGHLCQYDVDECASTP---CKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDP 572
Query: 362 ATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DMCLSQPCHGDAQCSTNPLTGSTLCLC 420
C GS C D V +F+CLC PG TG C + C SQPC C + LC C
Sbjct: 573 DPCHYGS-CKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRD--NAYLCFC 629
Query: 421 QPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECL 480
G +GP C +LD+C SPC+ G+CL+ + C C PGYTGS C + +EC
Sbjct: 630 LKGTTGPNCEINLDDC-----ASSPCD-SGTCLDKIDGYECACEPGYTGSMCNINIDECA 683
Query: 481 SQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICL 540
PCH G TC D + F C CP G C E NEC S PC+ H C D LNG++C C
Sbjct: 684 GNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNECNSNPCV-HGACRDSLNGYKCDCD 742
Query: 541 PGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPV 600
PG+SGT C+ + +EC S+PC NGG C+D + C C GF GP CQT ++EC S+PC
Sbjct: 743 PGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNINECASNPCLN 802
Query: 601 GASCLDLPGAFFCLCPSGFTGQLCEVPL--CAPNLCQPKQICKDQKD--KANCLCPDGSP 656
+C+D + C C +TG CEV L CAP+ C+ C+ +D +C+CP G
Sbjct: 803 QGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQ 862
Query: 657 G--CAPPEDNCT---CHHG-HCQRSS----CVCDVGWTGPECEAELGGCISAPCAHGGTC 706
G C + C C HG CQ + C C G++G CE ++ C PC +GG+C
Sbjct: 863 GQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSC 922
Query: 707 YPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQT 766
+ C C G+ G C E++ C S PC NG +C Y CTCP +G C+
Sbjct: 923 TDGINTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCEN 982
Query: 767 STDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQ 826
+T C + CFNGGTCV+ +F+CLC GF G C+ + C PC + TCQD
Sbjct: 983 NTPDCTESSCFNGGTCVDGINSFTCLCPPGFTGSYCQHDVN-ECDSQPCLHGGTCQDGCG 1041
Query: 827 GPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSC 886
RC CP GYTG +CQ L+ C PC C QT + C C GWTG C++P SC
Sbjct: 1042 SYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQYRCECPSGWTGLYCDVPSVSC 1101
Query: 887 QKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCM 946
+ AA QG+DV+ LC +GGLCVD+G ++ C C G+ GS C+D V+ C PCQNGATC
Sbjct: 1102 EVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGATCT 1161
Query: 947 AQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKP------------------- 987
GY C+C GY G NCS+E+D C S PC N GTC P
Sbjct: 1162 DYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHCEIN 1221
Query: 988 ---------------------------GGFHCACPPGFVGLRCEGDVDECLDQPCHPTGT 1020
GG+ C CPPGFVG RCEGDV+ECL PC GT
Sbjct: 1222 VDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNECLSNPCDARGT 1281
Query: 1021 AACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFE 1080
C N F+C+C GHTG+ CE I+ C +PC +GGTC + + GFIC CP GFE
Sbjct: 1282 QNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFE 1341
Query: 1081 GPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPC 1140
G TC + A +CG C +GG C+ P+ P C CL + GP+C P A C +PC
Sbjct: 1342 GATCENDARTCGSLRCLNGGTCISGPRS---PTCLCLGPFTGPECQFP-ASSPCLGGNPC 1397
Query: 1141 LYNGSCSETTGLGGPGFRCSCPHSSPGPRCQK-----PGAKG----------------CE 1179
G+C T+ P +RC CP G C G G C+
Sbjct: 1398 YNQGTCEPTSE--SPFYRCLCPAKFNGLLCHILDYSFGGGAGRDIPPPLIEEACELPECQ 1455
Query: 1180 GRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECL 1239
+G+ C C+ WDGGDCSL DPWK C +CW F DG C QC+S CL
Sbjct: 1456 EDAGNKVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGCL 1515
Query: 1240 FDGYDCETPPA-CTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRPEDGDPEWGPSLA 1298
FDG+DC+ C P YDQYC DHF +GHC++GCN+AEC WDG DC + +L
Sbjct: 1516 FDGFDCQRAEGQCNPLYDQYCKDHFSDGHCDQGCNSAECEWDGLDCAEHVPERLAAGTLV 1575
Query: 1299 LLVVLSPPALDQQLFALARVLSLTLRVGLWVRKDRDGRDMVYPYPGARAEEKLGGTRDPT 1358
++V++ P L F R LS L + ++D G+ M++PY G R EE
Sbjct: 1576 VVVLMPPEQLRNSSFHFLRELSRVLHTNVVFKRDAHGQQMIFPYYG-REEELRKHPIKRA 1634
Query: 1359 YQERAAPQTQ---------PLG-------KETDSLSA-GFVVVMGVDLSRCGPDHPASRC 1401
+ AAP P G +E D + G +V + +D +C +S+C
Sbjct: 1635 AEGWAAPDALLGQVKASLLPGGSEGGRRRRELDPMDVRGSIVYLEIDNRQCV--QASSQC 1692
Query: 1402 PWDPGLLLRFLAAMAAVGALEPLLPGPLLAVHPHAGTAPPANQLPWPVLCSPVAGVILLA 1461
+ FL A+A++G+L +P + AV PP QL + + + A V+L
Sbjct: 1693 FQSATDVAAFLGALASLGSLN--IPYKIEAVQSETVEPPPPAQLHFMYVAA-AAFVLLFF 1749
Query: 1462 LGALLVLQLIRRRRREHGALWLPPGFTRRPRTQSAPHRRRPPLGEDSIGLKALKPKAEVD 1521
+G ++L R+RRR+HG LW P GF ++++ +RR PLGEDS+GLK LK +
Sbjct: 1750 VGCGVLLS--RKRRRQHGQLWFPEGFKV---SEASKKKRREPLGEDSVGLKPLKNAS--- 1801
Query: 1522 EDGVVMCSGPEEG------------EEVGQAEETGPPSTCQLWSLSGGCGA-LPQAAMLT 1568
DG +M E EE + + + W+ A L +AM
Sbjct: 1802 -DGALMDDNQNEWGDEDLETKKFRFEEPVVLPDLDDQTDHRQWTQQHLDAADLRMSAMAP 1860
Query: 1569 PPQESEMEAP--DLDTRGPDGVTPLMSAVCCGE-VQSGTFQGAWLGCPEPWEPLLDGGAC 1625
P + E++A D++ RGPDG TPLM A C G +++G + P + GA
Sbjct: 1861 TPPQGEVDADCMDVNVRGPDGFTPLMIASCSGGGLETGNSEEEE-DAPAVISDFIYQGAS 1919
Query: 1626 PQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAADAREVCQL 1685
T TGET LHLAAR+SR AA+RLLEA A+ N D GRTPLHAAV+ADA+ V Q+
Sbjct: 1920 LHNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVSADAQGVFQI 1979
Query: 1686 LLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTALHWAAAVN 1745
L+R+R T +DAR DGTTPL+LAARLAVE ++E+LI + ADV A D GK+ALHWAAAVN
Sbjct: 1980 LIRNRATDLDARMHDGTTPLILAARLAVEGMLEDLINSHADVNAVDDLGKSALHWAAAVN 2039
Query: 1746 NARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAGLAPAD 1805
N AA LL+ GA+KD Q+NRE+TPLFLAAREG+ E A++LL A R++ D P D
Sbjct: 2040 NVDAAVVLLKNGANKDMQNNREETPLFLAAREGSYETAKVLLDHFANRDITDHMDRLPRD 2099
Query: 1806 VAHQRNHWDLLTLLE 1820
+A +R H D++ LL+
Sbjct: 2100 IAQERMHHDIVRLLD 2114
Score = 1050 bits (2714), Expect = 0.0
Identities = 526/1366 (38%), Positives = 692/1366 (50%), Gaps = 133/1366 (9%)
Query: 3 PPSLLLLLLLLLLLCVSVVRPRGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETC 62
PP L LL L LL ++ PR C E C NGG C + + G C C F+G C
Sbjct: 2 PPLLAPLLCLALLPALAARGPR---CSQPGETCLNGGKCEAAN-GTEACVCGGAFVGPRC 57
Query: 63 QFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPC 122
Q P+PC + C+N G+C + + + C+C GF+G C L++ C
Sbjct: 58 QDPNPCLSTP-CKNAGTCHVVDRRGVA----------DYACSCALGFSGPLCLTPLDNAC 106
Query: 123 PPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHC 182
+ C G C + +C C PGW+G+ CQ D C++NPC NGG CL CHC
Sbjct: 107 LTNPCRNGGTCDLLTLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHC 166
Query: 183 PPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRG 242
PP F G C +DVNEC Q PG C G +CHN +GS++C+C GP CE PC P
Sbjct: 167 PPSFHGPTCRQDVNECGQKPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSP 226
Query: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLC 302
C NGGTC+ P D T H C C PGF G +CE N D+C + C+NGG C DG++TY C C
Sbjct: 227 CQNGGTCR--PTGDVT-HECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRC 283
Query: 303 PETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAA 362
P WTG C+EDVDEC+ P C+NGGTC N+ G ++CVCV+GW G C EN+DDC +A
Sbjct: 284 PPEWTGQYCTEDVDECQLM-PNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASA 342
Query: 363 TCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQP 422
C G+TC DRV SF C CP GRTGLLCHL D C+S PC+ + C TNP+ G +C C
Sbjct: 343 ACFHGATCHDRVASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPS 402
Query: 423 GYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQ 482
GY+GP C QD+DEC + G +PCEH G C+NT GSF C C GYTG RCE D NEC+S
Sbjct: 403 GYTGPACSQDVDECSL---GANPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSN 459
Query: 483 PCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPG 542
PC +TCLD + F C+C PG EG CEV T+ECAS+PCL++ C D +N FQC C G
Sbjct: 460 PCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTG 519
Query: 543 FSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGA 602
F+G C+ D+DEC S+PC NG +C D P + C C G+ G C+ ++DEC DPC G
Sbjct: 520 FTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYG- 578
Query: 603 SCLDLPGAFFCLCPSGFTGQLCEVPL--CAPNLCQPKQICKDQKDKANCLCPDGS--PGC 658
SC D F CLC G+TG CE + C+ C+ C+D+ + C C G+ P C
Sbjct: 579 SCKDGVATFTCLCRPGYTGHHCETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNC 638
Query: 659 APPEDNCT---CHHGHC----QRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPS 711
D+C C G C C C+ G+TG C + C PC +GGTC +
Sbjct: 639 EINLDDCASSPCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGIN 698
Query: 712 GYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYC 771
G+ C CP GY PTC E+ C+S PC++ G+C S GY C C P +G C + + C
Sbjct: 699 GFTCRCPEGYHDPTCLSEVNECNSNPCVH-GACRDSLNGYKCDCDPGWSGTNCDINNNEC 757
Query: 772 VSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCL 831
S PC NGGTC + + C C GF GP C+ + CA +PC N+ TC D G +C
Sbjct: 758 ESNPCVNGGTCKDMTSGYVCTCREGFSGPNCQTNIN-ECASNPCLNQGTCIDDVAGYKCN 816
Query: 832 CPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTG--PSFHCLCLQGWTGPLCNLPLSSCQKA 889
C YTG +C+ ++ CA PC C Q+ SF C+C GW G C + ++ C
Sbjct: 817 CLLPYTGATCEVVLAPCAPSPCRNGGECRQSEDYESFSCVCPTGWQGQTCEVDINEC--- 873
Query: 890 ALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQP 949
V S C +G C ++ Y CHC G+ G C+ ++ C PC NG +C
Sbjct: 874 -------VLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETDIDDCRPNPCHNGGSCTDGI 926
Query: 950 SGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDE 1009
+ C C PG+ G C ++++ C S PC N CT + C CP GF G+ CE + +
Sbjct: 927 NTAFCDCLPGFRGTFCEEDINECASDPCRNGANCTDCVDSYTCTCPAGFSGIHCENNTPD 986
Query: 1010 CLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPL 1069
C + C GT C N+F C C PG TG +C+ +++ C SQPC HGGTC+ GS
Sbjct: 987 CTESSCFNGGT--CVDGINSFTCLCPPGFTGSYCQHDVNECDSQPCLHGGTCQDGCGS-- 1042
Query: 1070 GFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPP 1129
+ C CP+G+ GP C + C C +GG C + RC C SG+ G C P
Sbjct: 1043 -YRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHT---QYRCECPSGWTGLYCDVPS 1098
Query: 1130 AP-------KGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQ--------KPG 1174
+G C + G C + G C C G C+ P
Sbjct: 1099 VSCEVAAQRQGVDVARLCQHGGLCVD----AGNTHHCRCQAGYTGSYCEDLVDECSPSPC 1154
Query: 1175 AKG--CEGRSGDGACDAGCSGPGGN-------------WDGGDCSLGVPDPWK-GCPSHS 1218
G C G +C G N +GG C L +P+ +K CP +
Sbjct: 1155 QNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTC-LDLPNTYKCSCPRGT 1213
Query: 1219 R---CWLLFRDGQCHPQCD----SEECL--------FDGYDCETPPA------------- 1250
+ C + D C+P D S +C GY C PP
Sbjct: 1214 QGVHCEINVDD--CNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDVNEC 1271
Query: 1251 ----CTPAYDQYCHDHFHNGHCE-------KGCNTAECGWDGGDCR 1285
C Q C ++ HCE + C + G G C+
Sbjct: 1272 LSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCK 1317
Score = 79.0 bits (193), Expect = 4e-14
Identities = 90/356 (25%), Positives = 128/356 (35%), Gaps = 102/356 (28%)
Query: 22 RPRGLLCGSFPEPCANGGTC-LSLSLGQG-TCQCAPGFLGETCQFPDPCQNAQLCQNGGS 79
R ++ G +PC NGGTC ++ + +G C+C GF G TC+ + C NGG+
Sbjct: 1303 RCESVINGCKGKPCKNGGTCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGT 1362
Query: 80 CQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPC-PPSFCSKRGRCH-IQA 137
C + P SP+ C CL FTG CQ PC + C +G C
Sbjct: 1363 C-------ISGPRSPT-------CLCLGPFTGPECQFPASSPCLGGNPCYNQGTCEPTSE 1408
Query: 138 SGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNE 197
S +C C + G C + D+ GG PP ACE + E
Sbjct: 1409 SPFYRCLCPAKFNGLLCHILDY-----SFGGGA--------GRDIPPPLIEEACE--LPE 1453
Query: 198 CFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDS 257
C +D G N + S QC N C
Sbjct: 1454 CQEDAG---------NKVCSLQC------------------------NNHAC-------- 1472
Query: 258 TFHLCLCPPGFIGPDCEVNPD----NCV-SHQCQ---NGGTCQDGLDTYTCLCPETWTGW 309
G+ G DC +N + NC S QC + G C ++ CL + G+
Sbjct: 1473 ---------GWDGGDCSLNFNDPWKNCTQSLQCWKYFSDGHCDSQCNSAGCL----FDGF 1519
Query: 310 DCSEDVDECETQGPPHCR---NGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAA 362
DC +C +C+ + G C S C W G C E++ + +AA
Sbjct: 1520 DCQRAEGQCNPLYDQYCKDHFSDGHCDQGCNSAEC----EWDGLDCAEHVPERLAA 1571
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 1334 bits (3452), Expect = 0.0
Identities = 789/2168 (36%), Positives = 1038/2168 (47%), Gaps = 333/2168 (15%)
Query: 3 PPSLLLLLLLLLLLCVSVVRPRGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETC 62
PP + L LLLLL P L GS PCANGG C L + C C PG++GE C
Sbjct: 21 PPPVRALPLLLLLAGPGAAAPP-CLDGS---PCANGGRCTQLPSREAACLCPPGWVGERC 76
Query: 63 QFPDPCQNAQLCQNGGSCQALLPA---------PLGLP----SSPSPLTPS--------- 100
Q DPC + C G CQ+ + A P G S P P S
Sbjct: 77 QLEDPCHSGP-CAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCS 135
Query: 101 ------FLCTCLPGFTGERCQAKLED---------------------------------- 120
FLC+C PG+ G C++ +++
Sbjct: 136 VGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRCQCPAGYTGPLCE 195
Query: 121 ----PCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR-DFCSANPCVNGGVCLATY 175
PC PS C G C C+C+PG+ G+ C++ D C + C+NGG C+
Sbjct: 196 NPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGV 255
Query: 176 PQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRA 235
C CPP + G C DV+EC P C G +C NTLG C+C G G C
Sbjct: 256 NTYNCQCPPEWTGQFCTEDVDECQLQPNACHNGGTCFNTLGGHSCVCVNGWTGESCSQNI 315
Query: 236 GPCPPRGCSNGGTCQLMPEKDSTFH----------------------------------- 260
C C +G TC ++ ++F+
Sbjct: 316 DDCATAVCFHGATCH---DRVASFYCACPMGKTGLLCHLDDACVSNPCHEDAICDTNPVN 372
Query: 261 ---LCLCPPGFIGPDCEVNPDNCV--SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDV 315
+C CPPGF G C+ + D C ++ C++ G C + ++ C C +TG C DV
Sbjct: 373 GRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRCVNTQGSFLCQCGRGYTGPRCETDV 432
Query: 316 DECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVG 375
+EC GP CRN TC + G F C+C++G+ GT CE ++D+C ++ C G C DRV
Sbjct: 433 NEC-LSGP--CRNQATCLDRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRVN 489
Query: 376 SFSCLCPPGRTGLLCHLE-DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLD 434
FSC CP G +G C L+ D C S PC A+C P C C G+ G C +++D
Sbjct: 490 GFSCTCPSGFSGSTCQLDVDECASTPCRNGAKCVDQP--DGYECRCAEGFEGTLCDRNVD 547
Query: 435 ECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLL 494
+C P PC HG C++ SF+C C PGYTG+RCE+ +EC SQPC G CLDL+
Sbjct: 548 DC-----SPDPCHHG-RCVDGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLDLV 601
Query: 495 ATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDE 554
+ C CP G G CEV ++CAS PC C D +N + C+C PGF+G C +I+E
Sbjct: 602 DKYLCRCPSGTTGVNCEVNIDDCASNPC-TFGVCRDGINRYDCVCQPGFTGPLCNVEINE 660
Query: 555 CRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCL 614
C SSPC GG C D F C C PG P C C +PC G C D PG F C+
Sbjct: 661 CASSPCGEGGSCVDGENGFRCLCPPGSLPPLCLPPSHPCAHEPCSHGI-CYDAPGGFRCV 719
Query: 615 CPSGFTGQLCEVPL----CAPNLCQPKQICKDQKDKANCLCPDGSPG-----CAPPEDNC 665
C G++G C L C C+ C +C CP G G +P N
Sbjct: 720 CEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMGFHCTCPPGVQGRQCELLSPCTPNP 779
Query: 666 TCHHGHCQRSS-----CVCDVGWTGPECEAELGGCIS-APCAHGGTCYPQPSGYNCTCPT 719
H G C+ + C C GW GP C+ ++ C APC G C ++CTC
Sbjct: 780 CEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNLAGSFSCTCHG 839
Query: 720 GYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPC--- 776
GYTGP+C +++ C PCLNGGSC G + C+C P GP+C D C+S PC
Sbjct: 840 GYTGPSCDQDINDCDPNPCLNGGSCQDGVGSFSCSCLPGFAGPRCARDVDECLSNPCGPG 899
Query: 777 ----------------------------------FNGGTCVNRPGTFSCLCAMGFQGPRC 802
FNGGTCV+ +FSCLC G+ G C
Sbjct: 900 TCTDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCVDGVNSFSCLCRPGYTGAHC 959
Query: 803 EGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQT 862
+ + P C PC + C + G RC C +TG CQTL+D C+++PC C+QT
Sbjct: 960 QHEADP-CLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQT 1018
Query: 863 GPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF 922
G +CLC GW+G LC++ C++AA G+ + LC GG CVD S++C CP G
Sbjct: 1019 GA--YCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGR 1076
Query: 923 QGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHN--- 979
GS C+ V+PC ++PCQ+G TC GY+C+C PGY+G NC ++D C SQPC +
Sbjct: 1077 TGSHCEQEVDPCLAQPCQHGGTCRGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGS 1136
Query: 980 ------------------------------------------HGTCTPKPGGFHCACPPG 997
+GTC GGF C CPPG
Sbjct: 1137 CIDLVARYLCSCPPGTLGVLCEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRCTCPPG 1196
Query: 998 FVGLRCEGDVDECLDQPCHPTGTAAC-HSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCF 1056
+ GLRCE D++EC CH T C F C C G +G C+ + PC SQPC
Sbjct: 1197 YTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSPCESQPCQ 1256
Query: 1057 HGGTCEATAG--SPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRC 1114
HGG C + G L F CHC + F GP C A SC C G C +P+ PRC
Sbjct: 1257 HGGQCRPSPGPGGGLTFTCHCAQPFWGPRCERVARSCRELQCPVGVPCQQTPRG---PRC 1313
Query: 1115 ACLSGYGGPDCLT-PPAPKGCGPPS----PCLYNGSCSETTGLGGPGFRCSCPHSSPGPR 1169
AC G GP C + P +P G S PCL+ GSC P FRC+C GPR
Sbjct: 1314 ACPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRPAPL--APFFRCACAQGWTGPR 1371
Query: 1170 CQKPGAK------------GCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSH 1217
C+ P A C+ + GD CD C+ PG WDGGDCSL V DPW+ C +
Sbjct: 1372 CEAPAAAPEVSEEPRCPRAACQAKRGDQRCDRECNSPGCGWDGGDCSLSVGDPWRQCEA- 1430
Query: 1218 SRCWLLFRDGQCHPQCDSEECLFDGYDCET---PPACTPAYDQYCHDHFHNGHCEKGCNT 1274
+CW LF + +C P C S CL+D +DC C P Y++YC DHF +G C++GCNT
Sbjct: 1431 LQCWRLFNNSRCDPACSSPACLYDNFDCHAGGRERTCNPVYEKYCADHFADGRCDQGCNT 1490
Query: 1275 AECGWDGGDCRPEDGDPEWGPSLALLVVLSPPALDQQLFALARVLSLTLRVGLWVRKDRD 1334
ECGWDG DC E L L V+L P L + + LS LR L R D
Sbjct: 1491 EECGWDGLDCASEVPALLARGVLVLTVLLPPEELLRSSADFLQRLSAILRTSLRFRLDAH 1550
Query: 1335 GRDMVYPYPGARAEEKLGGTRDPTYQERAAPQTQPLGK-ETDSLSAGFVVVMGVDLSRCG 1393
G+ MV+PY R +P ++P + E G VV++ +D C
Sbjct: 1551 GQAMVFPY------------------HRPSPGSEPRARRELAPEVIGSVVMLEIDNRLCL 1592
Query: 1394 PDHPASRCPWDPGLLLRFLAAMAAVGALEPLLPGPLLAVHPHAGTAPPANQLPW-PVLCS 1452
C D +L A++AV L+ P PL V PP +P P+L
Sbjct: 1593 QSPENDHCFPDAQSAADYLGALSAVERLD--FPYPLRDVRGEP-LEPPEPSVPLLPLL-- 1647
Query: 1453 PVAGVILLALGALLVLQLIRRRRREHGALWLPPGFTRRPRTQSAPHRRRPPLGEDSIGLK 1512
VAG +LL L L++ ++ RR+REH LW P GF+ S RR P+G+D++G+K
Sbjct: 1648 -VAGAVLL-LVILVLGVMVARRKREHSTLWFPEGFSLHKDVASGHKGRREPVGQDALGMK 1705
Query: 1513 ALKP----KAEVDEDGV-VMCSGPE--EGEEVGQAEETGPPSTCQLWSLSGGCGA---LP 1562
+ EV D + C + + EE G E C+ W+ A +
Sbjct: 1706 NMAKGESLMGEVATDWMDTECPEAKRLKVEEPGMGAEEAVD--CRQWTQHHLVAADIRVA 1763
Query: 1563 QAAMLTPPQ-ESEMEAPDLDTRGPDGVTPLMSAVCCGEVQSGTFQGAWLGCPEPWEP--- 1618
A LTPPQ +++ + D++ RGPDG TPLM A CG G + P P E
Sbjct: 1764 PAMALTPPQGDADADGMDVNVRGPDGFTPLMLASFCG----GALE------PMPTEEDEA 1813
Query: 1619 ----------LLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGR 1668
L+ GA A T TGET LHLAAR++R AA+RLL+AGA+ N D +GR
Sbjct: 1814 DDTSASIISDLICQGAQLGARTDRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGR 1873
Query: 1669 TPLHAAVAADAREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVG 1728
TPLH AV ADA+ V Q+L+R+R T +DAR DG+T L+LAARLAVE +VEELIA+ ADV
Sbjct: 1874 TPLHTAVTADAQGVFQILIRNRSTDLDARMADGSTALILAARLAVEGMVEELIASHADVN 1933
Query: 1729 ARDKWGKTALHWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLG 1788
A D+ GK+ALHWAAAVNN A +LL+ GA+KD QD++E+TPLFLAAREG+ E A+LLL
Sbjct: 1934 AVDELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLLLD 1993
Query: 1789 LGAARELRDQAGLAPADVAHQRNHWDLLTLLEGAGPPEARHKATPGREA-GPF--PRART 1845
A RE+ D P DVA +R H D++ LL+ P ++ PG GP P
Sbjct: 1994 HFANREITDHLDRLPRDVAQERLHQDIVRLLDQPSGP----RSPPGPHGLGPLLCPPGAF 2049
Query: 1846 VSVSVPPHGGGALPRCRTLSAGAGPRGGGACLQARTWSVDLAARGGGAYSHCRSLSGVGA 1905
+ G R AG GP+G + R + LA G A S +LS V +
Sbjct: 2050 LPGLKAAQSGSKKSRRPPGKAGLGPQGP----RGRGKKLTLACPGPLADSSV-TLSPVDS 2104
Query: 1906 GGGPTPRG 1913
P P G
Sbjct: 2105 LDSPRPFG 2112
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 1294 bits (3349), Expect = 0.0
Identities = 713/1907 (37%), Positives = 972/1907 (50%), Gaps = 188/1907 (9%)
Query: 32 PEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQ--------- 81
P PC NGGTC C C PGF G TC+ D C N + CQNGG C
Sbjct: 227 PSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDCPNHR-CQNGGVCVDGVNTYNCR 285
Query: 82 -----------------ALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPP 124
L P + + + C C+ G++G+ C ++D C
Sbjct: 286 CPPQWTGQFCTEDVDECLLQPNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDD-CAF 344
Query: 125 SFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYP---QIQCH 181
+ C+ C I C C G G C L D C +NPC G +C T P Q C
Sbjct: 345 ASCTPGSTC-IDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALC-DTNPLNGQYICT 402
Query: 182 CPPGFEGHACERDVNEC-FQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPP 240
CP G++G C DV+EC + PC C NT G+F C C G GPRCE+ C
Sbjct: 403 CPQGYKGADCTEDVDECAMANSNPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHS 462
Query: 241 RGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTC 300
C N TC +K F CLC PGF G CE+ + C S+ C N G C D ++ + C
Sbjct: 463 DPCQNDATCL---DKIGGF-TCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQC 518
Query: 301 LCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCI 360
LCP +TG C D+D+C + C NG C + + C C +G+ G CEEN+D+C
Sbjct: 519 LCPPGFTGPVCQIDIDDCSSTP---CLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCD 575
Query: 361 AATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DMCLSQPCHGDAQCSTNPLTGSTLCL 419
C G C D + S++C+C PG G +C + D C S PC D +C L C
Sbjct: 576 PDPCHHGQ-CQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCID--LVNGYQCN 632
Query: 420 CQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNEC 479
CQPG SG C + D+C +PC HG C++ ++C+C PG+TG RC D +EC
Sbjct: 633 CQPGTSGVNCEINFDDC-----ASNPCIHG-ICMDGINRYSCVCSPGFTGQRCNIDIDEC 686
Query: 480 LSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCIC 539
S PC G+TC++ + F C+CP G C + NEC S PC+ H +C L+G++C+C
Sbjct: 687 ASNPCRKGATCINGVNGFRCICPEGPHHPSCYSQVNECLSNPCI-HGNCTGGLSGYKCLC 745
Query: 540 LPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCP 599
G+ G CE D +EC S+PC NGG C + + C C GF+G CQ +DEC S+PC
Sbjct: 746 DAGWVGINCEVDKNECLSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNIDECASNPCL 805
Query: 600 VGASCLDLPGAFFCLCPSGFTGQLCEVPL--CAPNLCQPKQICKDQK--DKANCLCPDGS 655
+C D + C C +TG+ C+ L C+PN C+ +CK+ + CLC G
Sbjct: 806 NQGTCFDDISGYTCHCVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGW 865
Query: 656 PG--CAPPEDNCTC----HHGHCQRSS----CVCDVGWTGPECEAELGGCISAPCAHGGT 705
G C D C +HG C + C C G++G +CE ++ C++ PC +GG+
Sbjct: 866 QGQRCTIDIDECISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGS 925
Query: 706 CYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQ 765
C + ++C C G+TG C +M C S PC NGG+C+ Y C C G C+
Sbjct: 926 CMDGVNTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCE 985
Query: 766 TSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSP 825
+ + C + CFNGGTCV+ +FSCLC +GF G C ++ C+ PC N TC D
Sbjct: 986 NNINECTESSCFNGGTCVDGINSFSCLCPVGFTGSFCLHEIN-ECSSHPCLNEGTCVDGL 1044
Query: 826 QGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSS 885
RC CP GYTG +CQTL++LC++ PC C+Q CLC GW G C++P S
Sbjct: 1045 GTYRCSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVS 1104
Query: 886 CQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATC 945
C AA +G+ V LC + G+C+++G +++C CP G+ GS C++ ++ C S PCQ+GATC
Sbjct: 1105 CDIAASRRGVLVEHLCQHSGVCINAGNTHYCQCPLGYTGSYCEEQLDECASNPCQHGATC 1164
Query: 946 MAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGT----------------------- 982
GY C+C PGY G NC E+D CQ+QPC N GT
Sbjct: 1165 SDFIGGYRCECVPGYQGVNCEYEVDECQNQPCQNGGTCIDLVNHFKCSCPPGTRGLLCEE 1224
Query: 983 ----------------CTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSL 1026
C + GG+ C C PGF G RCEGD++ECL PC G+ C L
Sbjct: 1225 NIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEGSLDCIQL 1284
Query: 1027 ANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSH 1086
N + C C TG+ CE +D C PC +GGTC + P GFIC CP GF G C
Sbjct: 1285 TNDYLCVCRSAFTGRHCETFVDVCPQMPCLNGGTCAVASNMPDGFICRCPPGFSGARCQ- 1343
Query: 1087 RAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCG---PPSPCLYN 1143
SCG C G C+ + PRC C P+P+ C SPC +
Sbjct: 1344 --SSCGQVKCRKGEQCVHTAS---GPRCFC------------PSPRDCESGCASSPCQHG 1386
Query: 1144 GSCSETTGLGGPGFRCSCPHSSPGPRCQKPGA-----------KGCEGRSGDGACDAGCS 1192
GSC P + C C G RC+ A + C ++ DG CD C+
Sbjct: 1387 GSCHPQR--QPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADKARDGVCDEACN 1444
Query: 1193 GPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCETPPACT 1252
WDGGDCSL + +PW C S CW + + QC C++ ECLFD ++C+ + T
Sbjct: 1445 SHACQWDGGDCSLTMENPWANCSSPLPCW-DYINNQCDELCNTVECLFDNFECQ-GNSKT 1502
Query: 1253 PAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRPEDGDPEWGPSLALLVVLSPPALDQQL 1312
YD+YC DHF + HC++GCN+ ECGWDG DC + + +L ++V++ P L Q
Sbjct: 1503 CKYDKYCADHFKDNHCDQGCNSEECGWDGLDCAADQPENLAEGTLVIVVLMPPEQLLQDA 1562
Query: 1313 FALARVLSLTLRVGLWVRKDRDGRDMVYPYPGARAEEKLGGTRDPTYQERAAPQTQPLGK 1372
+ R L L L +++D G MVYPY G EK + R+ P
Sbjct: 1563 RSFLRALGTLLHTNLRIKRDSQGELMVYPYYG----EKSAAMKKQRMTRRSLP------G 1612
Query: 1373 ETDSLSAGFVVVMGVDLSRCGPDHPASRCPWDPGLLLRFLAAMAAVGALEPLLPGPLLAV 1432
E + AG V + +D +C D D AA+ A A++ L PL++V
Sbjct: 1613 EQEQEVAGSKVFLEIDNRQCVQDSDHCFKNTDAA------AALLASHAIQGTLSYPLVSV 1666
Query: 1433 HPHAGTAPPANQLPWPVLCSPVAGVILLALGALLVLQLIRRRRREHGALWLPPGFTRRPR 1492
+ T P QL + + + V + ++ LG ++ +R+R+HG+LWLP GFT R
Sbjct: 1667 VSESLT-PERTQLLYLLAVAVVIILFIILLGVIMA-----KRKRKHGSLWLPEGFTL--R 1718
Query: 1493 TQSAPHRRRPPLGEDSIGLKALKPKAEVDEDGVVMC---------SGPE----EGEEVGQ 1539
++ H+RR P+G+D++GLK L +V E ++ GP+ + E+
Sbjct: 1719 RDASNHKRREPVGQDAVGLKNL--SVQVSEANLIGTGTSEHWVDDEGPQPKKVKAEDEAL 1776
Query: 1540 AEETGPPSTCQLWSL----SGGCGALPQAAMLTPPQESEMEAPDLDTRGPDGVTPLMSAV 1595
E P + W+ + P A+ P E E++ D++ RGPDG TPLM A
Sbjct: 1777 LSEEDDPIDRRPWTQQHLEAADIRRTPSLALTPPQAEQEVDVLDVNVRGPDGCTPLMLAS 1836
Query: 1596 CCGEVQ--SGTFQGAWLGCPEPWEPLLDGGACPQAHTVGTGETPLHLAARFSRPTAARRL 1653
G S + A L+ GA QA T TGE LHLAAR+SR AA+RL
Sbjct: 1837 LRGGSSDLSDEDEDAEDSSANIITDLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRL 1896
Query: 1654 LEAGANPNQPDRAGRTPLHAAVAADAREVCQLLLRSRQTAVDARTEDGTTPLMLAARLAV 1713
L+AGA+ N D GR PLHAAVAADA+ V Q+L+R+R T +DAR DGTTPL+LAARLAV
Sbjct: 1897 LDAGADANAQDNMGRCPLHAAVAADAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAV 1956
Query: 1714 EDLVEELIAAQADVGARDKWGKTALHWAAAVNNARAARSLLQAGADKDAQDNREQTPLFL 1773
E +V ELI QADV A D GK+ALHWAAAVNN A LL+ GA++D QDN+E+TPLFL
Sbjct: 1957 EGMVAELINCQADVNAVDDHGKSALHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFL 2016
Query: 1774 AAREGAVEVAQLLLGLGAARELRDQAGLAPADVAHQRNHWDLLTLLE 1820
AAREG+ E A++LL A R++ D P DVA R H D++ LL+
Sbjct: 2017 AAREGSYEAAKILLDHFANRDITDHMDRLPRDVARDRMHHDIVRLLD 2063
Score = 1028 bits (2659), Expect = 0.0
Identities = 541/1374 (39%), Positives = 694/1374 (50%), Gaps = 137/1374 (9%)
Query: 4 PSLLLLLLLLLLLCVSVVRPRGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQ 63
P+LL LL L L C + L C EPC N G C++ G G C+C GFLGE CQ
Sbjct: 6 PALLWALLALWLCCAAPAH--ALQCRDGYEPCVNEGMCVTYHNGTGYCKCPEGFLGEYCQ 63
Query: 64 FPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCP 123
DPC+ + CQNGG+C A A LG + C C GFTGE CQ PC
Sbjct: 64 HRDPCEKNR-CQNGGTCVA--QAMLGKAT----------CRCASGFTGEDCQYSTSHPCF 110
Query: 124 PSF-CSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHC 182
S C G CH+ + +C+C G+TG++CQ D C ++PC NG C Q C C
Sbjct: 111 VSRPCLNGGTCHMLSRDTYECTCQVGFTGKECQWTDACLSHPCANGSTCTTVANQFSCKC 170
Query: 183 PPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRG 242
GF G CE DVNEC PG C G +C N GS+QC CP G G C+ PC P
Sbjct: 171 LTGFTGQKCETDVNEC-DIPGHCQHGGTCLNLPGSYQCQCPQGFTGQYCDSLYVPCAPSP 229
Query: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLC 302
C NGGTC+ D TF C C PGF G CE N D+C +H+CQNGG C DG++TY C C
Sbjct: 230 CVNGGTCR--QTGDFTFE-CNCLPGFEGSTCERNIDDCPNHRCQNGGVCVDGVNTYNCRC 286
Query: 303 PETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAA 362
P WTG C+EDVDEC Q P C+NGGTC N G + CVCV+GW G C EN+DDC A
Sbjct: 287 PPQWTGQFCTEDVDECLLQ-PNACQNGGTCANRNGGYGCVCVNGWSGDDCSENIDDCAFA 345
Query: 363 TCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQP 422
+C PGSTCIDRV SFSC+CP G+ GLLCHL+D C+S PCH A C TNPL G +C C
Sbjct: 346 SCTPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTNPLNGQYICTCPQ 405
Query: 423 GYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQ 482
GY G C +D+DEC MA +PCEH G C+NT G+F+C C GY G RCE D NEC S
Sbjct: 406 GYKGADCTEDVDECAMANS--NPCEHAGKCVNTDGAFHCECLKGYAGPRCEMDINECHSD 463
Query: 483 PCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPG 542
PC +TCLD + F CLC PG +G CE+E NEC S PC+N+ C D +N FQC+C PG
Sbjct: 464 PCQNDATCLDKIGGFTCLCMPGFKGVHCELEINECQSNPCVNNGQCVDKVNRFQCLCPPG 523
Query: 543 FSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGA 602
F+G C+ DID+C S+PC NG +C D P + C+C GF G C+ +D C DPC G
Sbjct: 524 FTGPVCQIDIDDCSSTPCLNGAKCIDHPNGYECQCATGFTGVLCEENIDNCDPDPCHHG- 582
Query: 603 SCLDLPGAFFCLCPSGFTGQLC--EVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG--C 658
C D ++ C+C G+ G +C ++ C + C C D + C C G+ G C
Sbjct: 583 QCQDGIDSYTCICNPGYMGAICSDQIDECYSSPCLNDGRCIDLVNGYQCNCQPGTSGVNC 642
Query: 659 APPEDNCT---CHHGHC----QRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPS 711
D+C C HG C R SCVC G+TG C ++ C S PC G TC +
Sbjct: 643 EINFDDCASNPCIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCRKGATCINGVN 702
Query: 712 GYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYC 771
G+ C CP G P+C ++ C S PC++ G+C GY C C G C+ + C
Sbjct: 703 GFRCICPEGPHHPSCYSQVNECLSNPCIH-GNCTGGLSGYKCLCDAGWVGINCEVDKNEC 761
Query: 772 VSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCL 831
+S PC NGGTC N + C C GF+G C+ + CA +PC N+ TC D G C
Sbjct: 762 LSNPCQNGGTCDNLVNGYRCTCKKGFKGYNCQVNI-DECASNPCLNQGTCFDDISGYTCH 820
Query: 832 CPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTG--PSFHCLCLQGWTGPLCNLPLSSCQKA 889
C YTG +CQT++ C+ PC + C ++ S+ CLC GW G C + + C
Sbjct: 821 CVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDEC--- 877
Query: 890 ALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQP 949
+S C N GLC ++ SY C CPPGF G C++ ++ C + PCQNG +CM
Sbjct: 878 -------ISKPCMNHGLCHNTQGSYMCECPPGFSGMDCEEDIDDCLANPCQNGGSCMDGV 930
Query: 950 SGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDE 1009
+ + C C PG+ G C +++ C S+PC N GTC+ + C C GF G+ CE +++E
Sbjct: 931 NTFSCLCLPGFTGDKCQTDMNECLSEPCKNGGTCSDYVNSYTCKCQAGFDGVHCENNINE 990
Query: 1010 CLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGS-- 1067
C + C GT C N+F C C G TG +C EI+ C S PC + GTC G+
Sbjct: 991 CTESSCFNGGT--CVDGINSFSCLCPVGFTGSFCLHEINECSSHPCLNEGTCVDGLGTYR 1048
Query: 1068 ---PLGFI------------------------------CHCPKGFEGPTCSHRAPSCGF- 1093
PLG+ C CP G+ G C SC
Sbjct: 1049 CSCPLGYTGKNCQTLVNLCSRSPCKNKGTCVQKKAESQCLCPSGWAGAYCDVPNVSCDIA 1108
Query: 1094 ---------HHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNG 1144
H C H G+C+ G C C GY G C C +PC +
Sbjct: 1109 ASRRGVLVEHLCQHSGVCI---NAGNTHYCQCPLGYTGSYC--EEQLDECA-SNPCQHGA 1162
Query: 1145 SCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGR--SGDGAC-----DAGCSGPGGN 1197
+CS+ G G+RC C G C+ C+ + G C CS P G
Sbjct: 1163 TCSDFIG----GYRCECVPGYQGVNCEYE-VDECQNQPCQNGGTCIDLVNHFKCSCPPGT 1217
Query: 1198 WDGGDCSLGVPDPWKG--CPSHSRCWLLFRDG----QCHPQCDSEECLFDGYDCETPPA- 1250
G C + D +G C + +C + R G +C P E C D +C + P
Sbjct: 1218 -RGLLCEENIDDCARGPHCLNGGQC--MDRIGGYSCRCLPGFAGERCEGDINECLSNPCS 1274
Query: 1251 ------CTPAYDQY---CHDHFHNGHCE---KGCNTAECGWDGGDCRPEDGDPE 1292
C + Y C F HCE C C +GG C P+
Sbjct: 1275 SEGSLDCIQLTNDYLCVCRSAFTGRHCETFVDVCPQMPC-LNGGTCAVASNMPD 1327
Score = 112 bits (281), Expect = 3e-24
Identities = 102/363 (28%), Positives = 138/363 (38%), Gaps = 62/363 (17%)
Query: 24 RGLLCGSFPEPCANGGTCLSLS-----LGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGG 78
RGLLC + CA G CL+ +G +C+C PGF GE C+ + C + G
Sbjct: 1218 RGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGERCEGDINECLSNPCSSEG 1277
Query: 79 SCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQAS 138
S + LT +LC C FTG C+ D CP C G C + AS
Sbjct: 1278 SLDCI------------QLTNDYLCVCRSAFTGRHCET-FVDVCPQMPCLNGGTCAV-AS 1323
Query: 139 GRPQ---CSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDV 195
P C C PG++G +CQ C C G C+ T +C CP CE
Sbjct: 1324 NMPDGFICRCPPGFSGARCQ--SSCGQVKCRKGEQCVHTASGPRCFCP---SPRDCESGC 1378
Query: 196 NECFQDPGPCPKGTSCH--NTLGSFQCLCPVGQEGPRCELRAGP--CPPRGC-------- 243
PC G SCH + C C G RCEL P PP C
Sbjct: 1379 AS-----SPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYCADK 1433
Query: 244 SNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCP 303
+ G C ++ H C + G DC + +N ++ C + C D ++ C
Sbjct: 1434 ARDGVC----DEACNSHAC----QWDGGDCSLTMENPWAN-CSSPLPCWDYINNQ---CD 1481
Query: 304 ETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHC--VCVS---GWGGTSCEENLDD 358
E +C D EC+ C+ C + HC C S GW G C + +
Sbjct: 1482 ELCNTVECLFDNFECQGNSKT-CKYDKYCADHFKDNHCDQGCNSEECGWDGLDCAADQPE 1540
Query: 359 CIA 361
+A
Sbjct: 1541 NLA 1543
Score = 38.1 bits (87), Expect = 0.087
Identities = 45/171 (26%), Positives = 56/171 (32%), Gaps = 46/171 (26%)
Query: 23 PRGLLCGSFPEPCANGGTC-LSLSLGQGTCQCAPGFLGETCQF--------PDPCQ---- 69
PR G PC +GG+C +CQCAP F G C+ P C
Sbjct: 1371 PRDCESGCASSPCQHGGSCHPQRQPPYYSCQCAPPFSGSRCELYTAPPSTPPATCLSQYC 1430
Query: 70 -------------NAQLCQ-NGGSCQALLPAPLGLPSSPSPLTPSF------LCT---CL 106
N+ CQ +GG C + P SSP P LC CL
Sbjct: 1431 ADKARDGVCDEACNSHACQWDGGDCSLTMENPWANCSSPLPCWDYINNQCDELCNTVECL 1490
Query: 107 PGFTGERCQAKLEDPCPPSFCS---KRGRCHIQASGRPQCSCMPGWTGEQC 154
F CQ + +C+ K C Q +C GW G C
Sbjct: 1491 --FDNFECQGNSKTCKYDKYCADHFKDNHCD-QGCNSEEC----GWDGLDC 1534
>gi|224451128 eyes shut homolog isoform 1 [Homo sapiens]
Length = 3144
Score = 501 bits (1289), Expect = e-141
Identities = 320/1108 (28%), Positives = 449/1108 (40%), Gaps = 117/1108 (10%)
Query: 93 SPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRP-QCSCMPGWTG 151
SP PL T F CQ L FCS G+C +A + C C P ++G
Sbjct: 157 SPCPLGLRLNVTVKQQF----CQESLSS----EFCSGHGKCLSEAWSKTYSCHCQPPFSG 208
Query: 152 EQCQLRDFCSANPCVNGGVCLATYPQ-----IQCHCPPGFEGHACERDVNECFQDPGPCP 206
+ CQ D CS PC N G C+ +C C P F G C + +C P C
Sbjct: 209 KYCQELDACSFKPCKNNGSCINKRENWDEQAYECVCHPPFTGKNCSEIIGQC--QPHVCF 266
Query: 207 KGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPP 266
G + T SF C C GP CE+ A PC G C S+ + CP
Sbjct: 267 HGNCSNITSNSFICECDEQFSGPFCEVSAKPCVSLLFWKRGICP----NSSSAYTYECPK 322
Query: 267 GFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHC 326
G + E + CQNG C + C+C +T C CE+
Sbjct: 323 GSSSQNGETDVSEFSLVPCQNGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFP---L 379
Query: 327 RNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDC--IAATCAPGSTCIDRVGSFSCLCPPG 384
RN TC+ + C C+SG+ +CE+ +D C ++ C C + +G F +C PG
Sbjct: 380 RNNATCKKCEKDYPCSCISGFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPG 439
Query: 385 RTGLLCHL--------EDMCL-SQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLD- 434
T C + +C HG Q L G G C +D
Sbjct: 440 CTKNPCWFLKNVYLIHQHLCYCGVTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDA 499
Query: 435 -----------------------ECLMAQQGPSP-CEHGGSCLNTPGS--FNCLCPPGYT 468
C +G C +G SCL+ S + LC +
Sbjct: 500 YFFLAANCTEDATYVNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWA 559
Query: 469 GSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLN-HAD 527
G+ + + C + C D + C C G+LC V + C ++ H
Sbjct: 560 GNMYLENTTDDQENECQHEAVCKDEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGL 619
Query: 528 CHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQ 587
C L + C L + CE D ++C+S+ C NG G F KC+PGF+G +C+
Sbjct: 620 CLALSHNCNCSGLQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCE 679
Query: 588 TEVDECLSDPCPVGASCLDLPGAFFC--------------LCPSGFTGQLCEVPL--CAP 631
++DEC S PC GA+C+D PG +FC LC G+ G CE + C
Sbjct: 680 IDIDECASHPCKNGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCIL 739
Query: 632 NLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSS----------CVCDV 681
N C+ CKD C+C G +++ C C+ +S C C
Sbjct: 740 NACEHNSTCKDLHLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTS 799
Query: 682 GWTGPECEAELGGCISAPCAHGGTCYPQ--PSGYNCTCPTGYTGPTCSEEMTACH--SGP 737
GWTG C E+ C S PC +GG C+ P + C CP YTG C + C P
Sbjct: 800 GWTGQNCSEEINECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNP 859
Query: 738 CLNGGSCNPS-PGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMG 796
C N +C +C C G C+ C+ C + G C + F C+C G
Sbjct: 860 CRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPG 919
Query: 797 FQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRN 856
F G CE ++ C+ PC+N TC D C C Y G C+ ++ C PC
Sbjct: 920 FSGSLCEIEIN-ECSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDE 978
Query: 857 SHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFC 916
+C+ ++CLC G+TG C + L C +S C + G+C+D Y C
Sbjct: 979 ENCVYRTDGYNCLCAPGYTGINCEINLDEC----------LSEPCLHDGVCIDGINHYTC 1028
Query: 917 HCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQP 976
C GF G+ C+ + N C S PC +G C + Y C C C +++ C S P
Sbjct: 1029 DCKSGFFGTHCETNANDCLSNPCLHGR-CTELINEYPCSCDADGTSTQCKIKINDCTSIP 1087
Query: 977 CHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPT----GTAACHSLANAFYC 1032
C N G C GF C CP G+ G CE +D C + + G + F C
Sbjct: 1088 CMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFDC 1147
Query: 1033 QCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCG 1092
+CLPG +GQ+CE+ I+ C S PC HG CE G++C C G+ G C + C
Sbjct: 1148 RCLPGFSGQFCEININECSSSPCLHGADCEDHIN---GYVCKCQPGWSGHHCENEL-ECI 1203
Query: 1093 FHHCHHGGLCLPSPKPGFPPRCACLSGY 1120
+ C H LC+ + +PG C C G+
Sbjct: 1204 PNSCVH-ELCMEN-EPG--STCLCTPGF 1227
Score = 477 bits (1228), Expect = e-134
Identities = 317/1098 (28%), Positives = 468/1098 (42%), Gaps = 161/1098 (14%)
Query: 33 EPCANGGTCLSLSLGQG-TCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLP 91
E C+ G CLS + + +C C P F G+ CQ D C + + C+N GSC +
Sbjct: 181 EFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQELDAC-SFKPCKNNGSC---------IN 230
Query: 92 SSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTG 151
+ ++ C C P FTG+ C +++ C P C G C S C C ++G
Sbjct: 231 KRENWDEQAYECVCHPPFTGKNC-SEIIGQCQPHVCF-HGNCSNITSNSFICECDEQFSG 288
Query: 152 EQCQLRDFCSANPCVN-----GGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCP 206
C++ SA PCV+ G+C + CP G E DV+E PC
Sbjct: 289 PFCEV----SAKPCVSLLFWKRGICPNSSSAYTYECPKGSSSQNGETDVSEF--SLVPCQ 342
Query: 207 KGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPP 266
GT C C+C C+ C N TC+ EKD + C C
Sbjct: 343 NGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKC-EKD---YPCSCIS 398
Query: 267 GFIGPDCEVNPDNC--VSHQCQNGGTCQDGLDTYTCLCPETWTGWDC---------SEDV 315
GF +CE D+C +S C N C + + + +C T C + +
Sbjct: 399 GFTEKNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHL 458
Query: 316 DECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGT---SCEENLDD--CIAATCAPGSTC 370
C C++ G Q F V G+ G+ C+ +D +AA C +T
Sbjct: 459 CYCGVTFHGICQDKGPAQ-----FEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATY 513
Query: 371 ID--RVGSFSCLCPPGRTGLLCHLEDMCLSQ----------------------------- 399
++ + SC P T +C CLS+
Sbjct: 514 VNDPEDNNSSCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQEN 573
Query: 400 PCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECL----MAQQG------------- 442
C +A C C C Y G C ++D CL ++ G
Sbjct: 574 ECQHEAVCKDE--INRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSG 631
Query: 443 -----------------PSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCH 485
+ C++G + + G F C PG+ G++CE D +EC S PC
Sbjct: 632 LQRYERNICEIDTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCK 691
Query: 486 PGSTCLD--------------LLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDL 531
G+TC+D ++ F CLC PG G CE + ++C C +++ C DL
Sbjct: 692 NGATCIDQPGNYFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDL 751
Query: 532 LNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVD 591
+QC+CL + G CE++ +EC+ +PC N C D ++ C+C G+ G C E++
Sbjct: 752 HLSYQCVCLSDWEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEIN 811
Query: 592 ECLSDPCPVGASCLD--LPGAFFCLCPSGFTGQLC--EVPLC--APNLCQPKQICKDQKD 645
EC SDPC G C + +PG F CLCP +TGQ C LC N C+ C D
Sbjct: 812 ECDSDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVD 871
Query: 646 -KANCLCPDGSPG--CAPPEDNC---TCH-HGHCQ----RSSCVCDVGWTGPECEAELGG 694
+C+C + G C +C +C +G C+ C+C G++G CE E+
Sbjct: 872 ANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINE 931
Query: 695 CISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCT 754
C S PC + GTC + + C C Y GP C ++ C PCL+ +C GY C
Sbjct: 932 CSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCL 991
Query: 755 CPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSP 814
C P +TG C+ + D C+S PC + G C++ ++C C GF G CE C +P
Sbjct: 992 CAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNAN-DCLSNP 1050
Query: 815 CRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGW 874
C + C + C C T C+ ++ C PC C ++ F C+C +G+
Sbjct: 1051 CLH-GRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGY 1109
Query: 875 TGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDS-GPSYFCHCPPGFQGSLCQDHVNP 933
TG C + +C + L+ S +C NGG+CVD G ++ C C PGF G C+ ++N
Sbjct: 1110 TGAYCEKSIDNCAEPELN-----SVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININE 1164
Query: 934 CESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCA 993
C S PC +GA C +GY+C+C PG+ G +C EL+ C C H C G C
Sbjct: 1165 CSSSPCLHGADCEDHINGYVCKCQPGWSGHHCENELE-CIPNSC-VHELCMENEPGSTCL 1222
Query: 994 CPPGF----VGLRCEGDV 1007
C PGF +GL C ++
Sbjct: 1223 CTPGFMTCSIGLLCGDEI 1240
Score = 392 bits (1006), Expect = e-108
Identities = 275/1058 (25%), Positives = 402/1058 (37%), Gaps = 208/1058 (19%)
Query: 282 SHQCQNGGTC--QDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGS- 338
S C G C + TY+C C ++G C E +D C + C+N G+C N +
Sbjct: 180 SEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQE-LDACSFKP---CKNNGSCINKRENW 235
Query: 339 ----FHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLED 394
+ CVC + G +C E + C C G+ SF C C +G C +
Sbjct: 236 DEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGNCSNITSNSFICECDEQFSGPFCEVS- 294
Query: 395 MCLSQPC-------HGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCE 447
++PC G S++ T C G S D+ E + PC+
Sbjct: 295 ---AKPCVSLLFWKRGICPNSSSAYTYE----CPKGSSSQNGETDVSEFSLV-----PCQ 342
Query: 448 HGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEG 507
+G C+ C+C P +T C++ C S P +TC + C C G
Sbjct: 343 NGTDCIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTE 402
Query: 508 QLCEVETNECA--SAPCLNHADCHDLLNGFQCICLPGFSGTRCE--EDIDECRSSPCANG 563
+ CE + C S CLN C +++ F+ +C+PG + C +++ C G
Sbjct: 403 KNCEKAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCG 462
Query: 564 ----GQCQDQ-PGAFHCKCLPGF---EGPRCQTEVD-------ECLSDP----------- 597
G CQD+ P F GF EG +CQ +D C D
Sbjct: 463 VTFHGICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNS 522
Query: 598 ------------CPVGASCLDLPGA----FFCLCPSGFTGQLCEVPLCAPNLCQPKQICK 641
C G SCL + + C L N CQ + +CK
Sbjct: 523 SCWFPHEGTKEICANGCSCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCK 582
Query: 642 DQKDKANCLCPDGSPG---------------------CAPPEDNCTCHH----------- 669
D+ ++ C C G C NC C
Sbjct: 583 DEINRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEI 642
Query: 670 --GHCQRSSCV---------------CDVGWTGPECEAELGGCISAPCAHGGTCYPQPS- 711
C+ +SC C G+ G +CE ++ C S PC +G TC QP
Sbjct: 643 DTEDCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGN 702
Query: 712 -------------GYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPS 758
G++C C GY G C +++ C C + +C Y C C
Sbjct: 703 YFCQCVPPFKVVDGFSCLCNPGYVGIRCEQDIDDCILNACEHNSTCKDLHLSYQCVCLSD 762
Query: 759 HTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNR 818
G C+ ++ C PC N TC + ++ C C G+ G C ++ C PC N
Sbjct: 763 WEGNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEIN-ECDSDPCMNG 821
Query: 819 ATCQDS--PQGPRCLCPTGYTGGSCQTLMDLC--AQKPCPRNSHCLQ-TGPSFHCLCLQG 873
C +S P CLCP YTG C +LC PC NS CL + HC+C +
Sbjct: 822 GLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQHCICREE 881
Query: 874 WTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNP 933
+ G C + + C + C + G C D ++ C C PGF GSLC+ +N
Sbjct: 882 FEGKNCEIDVKDCLFLS----------CQDYGDCEDMVNNFRCICRPGFSGSLCEIEINE 931
Query: 934 CESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCA 993
C S PC+N TC+ + + C C P Y G C +++ C+ PC + C + G++C
Sbjct: 932 CSSEPCKNNGTCVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCL 991
Query: 994 CPPGFVGLRCEGDVDECLDQPC-----------------------------------HPT 1018
C PG+ G+ CE ++DECL +PC +P
Sbjct: 992 CAPGYTGINCEINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPC 1051
Query: 1019 GTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKG 1078
C L N + C C T C+++I+ C S PC + G C+ +A GF C CP+G
Sbjct: 1052 LHGRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAH---GFTCICPRG 1108
Query: 1079 FEGPTCSHRAPSCGFHH-----CHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKG 1133
+ G C +C C +GG+C+ P F C CL G+ G C
Sbjct: 1109 YTGAYCEKSIDNCAEPELNSVICLNGGICVDGPGHTFD--CRCLPGFSGQFC--EININE 1164
Query: 1134 CGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQ 1171
C SPCL+ C + G+ C C G C+
Sbjct: 1165 CS-SSPCLHGADCEDHIN----GYVCKCQPGWSGHHCE 1197
Score = 390 bits (1003), Expect = e-108
Identities = 295/1089 (27%), Positives = 418/1089 (38%), Gaps = 185/1089 (16%)
Query: 319 ETQGPPHCRNGGTCQNSAGS--FHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDR--- 373
E+ C G C + A S + C C + G C+E LD C C +CI++
Sbjct: 176 ESLSSEFCSGHGKCLSEAWSKTYSCHCQPPFSGKYCQE-LDACSFKPCKNNGSCINKREN 234
Query: 374 --VGSFSCLCPPGRTGLLC-HLEDMCLSQPC-HGDAQCSTNPLTGSTLCLCQPGYSGPTC 429
++ C+C P TG C + C C HG+ CS N + S +C C +SGP C
Sbjct: 235 WDEQAYECVCHPPFTGKNCSEIIGQCQPHVCFHGN--CS-NITSNSFICECDEQFSGPFC 291
Query: 430 HQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGST 489
C+ G C N+ ++ CP G + E D +E PC G+
Sbjct: 292 EVSAKPCVSLLFWKR-----GICPNSSSAYTYECPKGSSSQNGETDVSEFSLVPCQNGTD 346
Query: 490 CLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCE 549
C+ + C+C P LC+ C S P N+A C + C C+ GF+ CE
Sbjct: 347 CIKISNDVMCICSPIFTDLLCKSIQTSCESFPLRNNATCKKCEKDYPCSCISGFTEKNCE 406
Query: 550 EDIDECR--SSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDP--CPVGAS-- 603
+ ID C+ S C N C + G F C+PG C + L C G +
Sbjct: 407 KAIDHCKLLSINCLNEEWCFNIIGRFKYVCIPGCTKNPCWFLKNVYLIHQHLCYCGVTFH 466
Query: 604 --CLDL-PGAFFCLCPSGFTG---QLCEVPL-----CAPNLCQPKQICKDQKDK-ANC-- 649
C D P F + GF G + C+ + A N + D +D ++C
Sbjct: 467 GICQDKGPAQFEYVWQLGFAGSEGEKCQGVIDAYFFLAANCTEDATYVNDPEDNNSSCWF 526
Query: 650 -------LCPDGSPGCAPPED-------------------NCT------CHH-----GHC 672
+C +G C ED N T C H
Sbjct: 527 PHEGTKEICANGC-SCLSEEDSQEYRYLCFLRWAGNMYLENTTDDQENECQHEAVCKDEI 585
Query: 673 QRSSCVCDVGWTGPECEAELGGCI-SAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMT 731
R C C + + G C + C+ + + G C NC+ Y C +
Sbjct: 586 NRPRCSCSLSYIGRLCVVNVDYCLGNHSISVHGLCLALSHNCNCSGLQRYERNICEIDTE 645
Query: 732 ACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGT--- 788
C S C NG + G ++ C P G QC+ D C S PC NG TC+++PG
Sbjct: 646 DCKSASCKNGTTSTHLRGYFFRKCVPGFKGTQCEIDIDECASHPCKNGATCIDQPGNYFC 705
Query: 789 -----------FSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYT 837
FSCLC G+ G RCE + C + C + +TC+D +C+C + +
Sbjct: 706 QCVPPFKVVDGFSCLCNPGYVGIRCEQDI-DDCILNACEHNSTCKDLHLSYQCVCLSDWE 764
Query: 838 GGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDV 897
G C+ + C PC NS C S+ C C GWTG C+ ++ C
Sbjct: 765 GNFCEQESNECKMNPCKNNSTCTDLYKSYRCECTSGWTGQNCSEEINECD---------- 814
Query: 898 SSLCHNGGLCVDSG-PSYF-CHCPPGFQGSLCQDHVNPCE--SRPCQNGATCMAQ-PSGY 952
S C NGGLC +S P F C CPP + G C N C+ PC+N +TC+A +
Sbjct: 815 SDPCMNGGLCHESTIPGQFVCLCPPLYTGQFCHQRYNLCDLLHNPCRNNSTCLALVDANQ 874
Query: 953 LCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLD 1012
C C ++G+NC ++ C C ++G C F C C PGF G CE +++EC
Sbjct: 875 HCICREEFEGKNCEIDVKDCLFLSCQDYGDCEDMVNNFRCICRPGFSGSLCEIEINECSS 934
Query: 1013 QPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFI 1072
+PC GT C L N F+C C P + G +CE++++ C PC C G+
Sbjct: 935 EPCKNNGT--CVDLTNRFFCNCEPEYHGPFCELDVNKCKISPCLDEENCVYRTD---GYN 989
Query: 1073 CHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGP-------DC 1125
C C G+ G C C C H G+C+ C C SG+ G DC
Sbjct: 990 CLCAPGYTGINCEINLDECLSEPCLHDGVCIDGINHY---TCDCKSGFFGTHCETNANDC 1046
Query: 1126 LTPPA------------PKGCGPPS---------------PCLYNGSCSETTGLGGPGFR 1158
L+ P P C PC+ G C ++ GF
Sbjct: 1047 LSNPCLHGRCTELINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQKSAH----GFT 1102
Query: 1159 CSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHS 1218
C CP G C+K E C +GG C G P H+
Sbjct: 1103 CICPRGYTGAYCEKSIDNCAEPELNSVIC----------LNGGICVDG--------PGHT 1144
Query: 1219 RCWLLFRDGQCHPQCDSEECLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAECG 1278
D +C P + C + +C + P C D C DH + C+ + G
Sbjct: 1145 ------FDCRCLPGFSGQFCEININECSSSP-CLHGAD--CEDHINGYVCK-----CQPG 1190
Query: 1279 WDGGDCRPE 1287
W G C E
Sbjct: 1191 WSGHHCENE 1199
Score = 217 bits (553), Expect = 8e-56
Identities = 121/402 (30%), Positives = 180/402 (44%), Gaps = 30/402 (7%)
Query: 27 LCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPA 86
LC PC N TCL+L C C F G+ C+ CQ+ G C+
Sbjct: 852 LCDLLHNPCRNNSTCLALVDANQHCICREEFEGKNCEIDVKDCLFLSCQDYGDCE----- 906
Query: 87 PLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCM 146
+ +F C C PGF+G C+ ++ + C C G C + + R C+C
Sbjct: 907 ---------DMVNNFRCICRPGFSGSLCEIEINE-CSSEPCKNNGTC-VDLTNRFFCNCE 955
Query: 147 PGWTGEQCQLR-DFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPC 205
P + G C+L + C +PC++ C+ C C PG+ G CE +++EC + PC
Sbjct: 956 PEYHGPFCELDVNKCKISPCLDEENCVYRTDGYNCLCAPGYTGINCEINLDECLSE--PC 1013
Query: 206 PKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCP 265
C + + + C C G G CE A C C +G +L+ E + C C
Sbjct: 1014 LHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNPCLHGRCTELINE-----YPCSCD 1068
Query: 266 PGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQ--GP 323
C++ ++C S C N G CQ +TC+CP +TG C + +D C
Sbjct: 1069 ADGTSTQCKIKINDCTSIPCMNEGFCQKSAHGFTCICPRGYTGAYCEKSIDNCAEPELNS 1128
Query: 324 PHCRNGGTCQNSAG-SFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCP 382
C NGG C + G +F C C+ G+ G CE N+++C ++ C G+ C D + + C C
Sbjct: 1129 VICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSPCLHGADCEDHINGYVCKCQ 1188
Query: 383 PGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGY 424
PG +G C E C+ C + P GST CLC PG+
Sbjct: 1189 PGWSGHHCENELECIPNSCVHELCMENEP--GST-CLCTPGF 1227
Score = 180 bits (456), Expect = 1e-44
Identities = 108/377 (28%), Positives = 159/377 (42%), Gaps = 56/377 (14%)
Query: 35 CANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSP 94
C + G C + + C C PGF G C+ +++ C+N G+C
Sbjct: 899 CQDYGDCEDM-VNNFRCICRPGFSGSLCEIEINECSSEPCKNNGTCV------------- 944
Query: 95 SPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQC 154
LT F C C P + G C+ + + C S C C + G C C PG+TG C
Sbjct: 945 -DLTNRFFCNCEPEYHGPFCELDV-NKCKISPCLDEENCVYRTDGY-NCLCAPGYTGINC 1001
Query: 155 QLR-DFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHN 213
++ D C + PC++ GVC+ C C GF G CE + N+C +P C G C
Sbjct: 1002 EINLDECLSEPCLHDGVCIDGINHYTCDCKSGFFGTHCETNANDCLSNP--CLHGR-CTE 1058
Query: 214 TLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDC 273
+ + C C +C+++ C C N G CQ K + C+CP G+ G C
Sbjct: 1059 LINEYPCSCDADGTSTQCKIKINDCTSIPCMNEGFCQ----KSAHGFTCICPRGYTGAYC 1114
Query: 274 EVNPDNCVSHQ-----CQNGGTCQDGLD-TYTCLCPETWTGWDCSEDVDECETQGPPHCR 327
E + DNC + C NGG C DG T+ C C ++G C +++EC + C
Sbjct: 1115 EKSIDNCAEPELNSVICLNGGICVDGPGHTFDCRCLPGFSGQFCEININECSSSP---CL 1171
Query: 328 NGGTCQNSAGSFHCVCVSGWGGTSCEENLD------------------DCIAA----TCA 365
+G C++ + C C GW G CE L+ C+ TC+
Sbjct: 1172 HGADCEDHINGYVCKCQPGWSGHHCENELECIPNSCVHELCMENEPGSTCLCTPGFMTCS 1231
Query: 366 PGSTCIDRVGSFSCLCP 382
G C D + +CL P
Sbjct: 1232 IGLLCGDEIRRITCLTP 1248
Score = 70.5 bits (171), Expect = 2e-11
Identities = 30/74 (40%), Positives = 42/74 (56%), Gaps = 5/74 (6%)
Query: 901 CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCE-----SRPCQNGATCMAQPSGYLCQ 955
C NGG C++SG S +C+C G++GS C + V+ C+ C GATC++ P GY C
Sbjct: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCF 2678
Query: 956 CAPGYDGQNCSKEL 969
C G G C + L
Sbjct: 2679 CPLGTTGIYCEQAL 2692
Score = 65.9 bits (159), Expect = 4e-10
Identities = 30/80 (37%), Positives = 42/80 (52%), Gaps = 6/80 (7%)
Query: 326 CRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAA-----TCAPGSTCIDRVGSFSCL 380
C NGGTC S S +C C +GW G+ C E + C C+ G+TCI ++C
Sbjct: 2619 CGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCF 2678
Query: 381 CPPGRTGLLCHLEDMCLSQP 400
CP G TG+ C + + +S P
Sbjct: 2679 CPLGTTGIYCE-QALSISDP 2697
Score = 65.5 bits (158), Expect = 5e-10
Identities = 29/90 (32%), Positives = 40/90 (44%), Gaps = 5/90 (5%)
Query: 920 PGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQ---- 975
P S+ Q H +PC C NG TC+ + C C G+ G C++ + C +
Sbjct: 2600 PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPP 2659
Query: 976 -PCHNHGTCTPKPGGFHCACPPGFVGLRCE 1004
C TC P G+ C CP G G+ CE
Sbjct: 2660 HHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 63.9 bits (154), Expect = 1e-09
Identities = 34/115 (29%), Positives = 50/115 (43%), Gaps = 4/115 (3%)
Query: 134 HIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACER 193
H + G P+ G + QC CS C NGG C+ + + C+C G++G C
Sbjct: 2589 HFRGLGNPEGHPNAGRSVGQCHASP-CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTE 2647
Query: 194 DVNECFQDPGP---CPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSN 245
V+ C + P C +G +C + + C CP+G G CE P SN
Sbjct: 2648 TVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALSISDPSFRSN 2702
Score = 63.9 bits (154), Expect = 1e-09
Identities = 34/102 (33%), Positives = 48/102 (47%), Gaps = 12/102 (11%)
Query: 686 PECEAELGGCISAPCA-----HGGTCYPQPSGYNCTCPTGYTGPTCSEEMTAC---HSGP 737
P +G C ++PC+ +GGTC + C C TG+ G C+E ++ C H P
Sbjct: 2600 PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPP 2659
Query: 738 --CLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCF 777
C G +C P GY C CP TG C+ + +S P F
Sbjct: 2660 HHCSRGATCISLPHGYTCFCPLGTTGIYCEQALS--ISDPSF 2699
Score = 63.9 bits (154), Expect = 1e-09
Identities = 32/89 (35%), Positives = 44/89 (49%), Gaps = 14/89 (15%)
Query: 552 IDECRSSPCA-----NGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDP-------CP 599
+ +C +SPC+ NGG C + + +C C G++G C V C DP C
Sbjct: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTC--DPEHDPPHHCS 2663
Query: 600 VGASCLDLPGAFFCLCPSGFTGQLCEVPL 628
GA+C+ LP + C CP G TG CE L
Sbjct: 2664 RGATCISLPHGYTCFCPLGTTGIYCEQAL 2692
Score = 63.5 bits (153), Expect = 2e-09
Identities = 38/116 (32%), Positives = 49/116 (42%), Gaps = 9/116 (7%)
Query: 248 TCQLMPEKDSTFHLCLCPPGFIGP-----DCEVNPDNCVSHQCQNGGTCQDGLDTYTCLC 302
T Q+ EKD F P G C +P C +C NGGTC + + C C
Sbjct: 2579 TLQVRTEKDGHFRGLGNPEGHPNAGRSVGQCHASP--CSLMKCGNGGTCIESGTSVYCNC 2636
Query: 303 PETWTGWDCSEDVDECETQGPP--HCRNGGTCQNSAGSFHCVCVSGWGGTSCEENL 356
W G C+E V C+ + P HC G TC + + C C G G CE+ L
Sbjct: 2637 TTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQAL 2692
Score = 62.0 bits (149), Expect = 6e-09
Identities = 28/75 (37%), Positives = 39/75 (52%), Gaps = 3/75 (4%)
Query: 900 LCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQP-SGYLCQCAP 958
LC N G C+ + FC CP + G LCQ CE+ PC NGATC+ + + +C C
Sbjct: 2343 LCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVCLCPY 2400
Query: 959 GYDGQNCSKELDACQ 973
G G C+ ++ Q
Sbjct: 2401 GRSGPLCTDAINITQ 2415
Score = 58.2 bits (139), Expect = 8e-08
Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 5/86 (5%)
Query: 695 CISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPG-GYYC 753
C C + GTC C CP Y+G C + +C + PC NG +C P G C
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENNPCGNGATCVPKSGTDIVC 2396
Query: 754 TCPPSHTGPQCQTSTDYCVSAPCFNG 779
CP +GP C + + ++ P F+G
Sbjct: 2397 LCPYGRSGPLCTDAIN--ITQPRFSG 2420
Score = 58.2 bits (139), Expect = 8e-08
Identities = 28/71 (39%), Positives = 36/71 (50%), Gaps = 3/71 (4%)
Query: 733 CHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGT-FSC 791
C C N G+C +C CP ++G CQ ++ C + PC NG TCV + GT C
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFAS--CENNPCGNGATCVPKSGTDIVC 2396
Query: 792 LCAMGFQGPRC 802
LC G GP C
Sbjct: 2397 LCPYGRSGPLC 2407
Score = 57.4 bits (137), Expect = 1e-07
Identities = 27/75 (36%), Positives = 36/75 (48%), Gaps = 3/75 (4%)
Query: 930 HVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPG- 988
HV C C+N TC++ C+C Y G+ C + +C++ PC N TC PK G
Sbjct: 2335 HVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENNPCGNGATCVPKSGT 2392
Query: 989 GFHCACPPGFVGLRC 1003
C CP G G C
Sbjct: 2393 DIVCLCPYGRSGPLC 2407
Score = 56.2 bits (134), Expect = 3e-07
Identities = 26/66 (39%), Positives = 36/66 (54%), Gaps = 2/66 (3%)
Query: 326 CRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCI-DRVGSFSCLCPPG 384
CRNGG C + +F C C+ W G +C +++ C+ C S CI D+ S+SCLC G
Sbjct: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSCLCTLG 2942
Query: 385 RTGLLC 390
G C
Sbjct: 2943 WVGRYC 2948
Score = 55.8 bits (133), Expect = 4e-07
Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 731 TACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCV-NRPGTF 789
TAC C NGG C + + C C P G C S C++ C + C+ ++ ++
Sbjct: 2877 TACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSFSY 2935
Query: 790 SCLCAMGFQGPRCEGKLRPSCA 811
SCLC +G+ G CE K S A
Sbjct: 2936 SCLCTLGWVGRYCENKTSFSTA 2957
Score = 55.5 bits (132), Expect = 5e-07
Identities = 28/73 (38%), Positives = 35/73 (47%), Gaps = 3/73 (4%)
Query: 808 PSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCL-QTGPSF 866
P CA CRN TC + C CP Y+G CQ C PC + C+ ++G
Sbjct: 2337 PWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDI 2394
Query: 867 HCLCLQGWTGPLC 879
CLC G +GPLC
Sbjct: 2395 VCLCPYGRSGPLC 2407
Score = 55.1 bits (131), Expect = 7e-07
Identities = 27/94 (28%), Positives = 37/94 (39%), Gaps = 7/94 (7%)
Query: 835 GYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQG 894
G + G C C+ C C+++G S +C C GW G C +S+C
Sbjct: 2603 GRSVGQCHA--SPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEH---- 2656
Query: 895 IDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQ 928
D C G C+ Y C CP G G C+
Sbjct: 2657 -DPPHHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 55.1 bits (131), Expect = 7e-07
Identities = 26/72 (36%), Positives = 38/72 (52%), Gaps = 2/72 (2%)
Query: 555 CRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCL-DLPGAFFC 613
C + C NGG+C F C+CLP + G C V CL++ C + C+ D ++ C
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSC 2937
Query: 614 LCPSGFTGQLCE 625
LC G+ G+ CE
Sbjct: 2938 LCTLGWVGRYCE 2949
Score = 53.5 bits (127), Expect = 2e-06
Identities = 27/90 (30%), Positives = 36/90 (40%), Gaps = 3/90 (3%)
Query: 384 GRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGP 443
GR+ CH C C C + S C C G+ G C + + C P
Sbjct: 2603 GRSVGQCHASP-CSLMKCGNGGTCIESGT--SVYCNCTTGWKGSFCTETVSTCDPEHDPP 2659
Query: 444 SPCEHGGSCLNTPGSFNCLCPPGYTGSRCE 473
C G +C++ P + C CP G TG CE
Sbjct: 2660 HHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 53.1 bits (126), Expect = 3e-06
Identities = 27/81 (33%), Positives = 40/81 (49%), Gaps = 5/81 (6%)
Query: 313 EDVDECETQGPPH--CRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTC 370
++++ C H CRN GTC + + C C + G C+ C C G+TC
Sbjct: 2329 KNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATC 2386
Query: 371 IDRVGS-FSCLCPPGRTGLLC 390
+ + G+ CLCP GR+G LC
Sbjct: 2387 VPKSGTDIVCLCPYGRSGPLC 2407
Score = 53.1 bits (126), Expect = 3e-06
Identities = 35/114 (30%), Positives = 45/114 (39%), Gaps = 13/114 (11%)
Query: 232 ELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDC-----EVNPDNCVSHQCQ 286
+ A PC C NGGTC + T C C G+ G C +P++ H C
Sbjct: 2608 QCHASPCSLMKCGNGGTC----IESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCS 2663
Query: 287 NGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFH 340
G TC YTC CP TG C + + + P R+ S SFH
Sbjct: 2664 RGATCISLPHGYTCFCPLGTTGIYCEQALSISD----PSFRSNELSWMSFASFH 2713
Score = 52.8 bits (125), Expect = 3e-06
Identities = 31/90 (34%), Positives = 40/90 (44%), Gaps = 8/90 (8%)
Query: 763 QCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCA---DSP--CRN 817
QC S C C NGGTC+ + C C G++G C + +C D P C
Sbjct: 2608 QCHASP--CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVS-TCDPEHDPPHHCSR 2664
Query: 818 RATCQDSPQGPRCLCPTGYTGGSCQTLMDL 847
ATC P G C CP G TG C+ + +
Sbjct: 2665 GATCISLPHGYTCFCPLGTTGIYCEQALSI 2694
Score = 51.6 bits (122), Expect = 8e-06
Identities = 26/90 (28%), Positives = 40/90 (44%), Gaps = 5/90 (5%)
Query: 427 PTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQ---- 482
P + + +C + C +GG+C+ + S C C G+ GS C + C +
Sbjct: 2600 PNAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPP 2659
Query: 483 -PCHPGSTCLDLLATFHCLCPPGLEGQLCE 511
C G+TC+ L + C CP G G CE
Sbjct: 2660 HHCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 51.2 bits (121), Expect = 1e-05
Identities = 26/81 (32%), Positives = 39/81 (48%), Gaps = 6/81 (7%)
Query: 152 EQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSC 211
E C + +C+ + C N G C++ + C CP + G C+ C + PC G +C
Sbjct: 2332 ENCHV-PWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASC--ENNPCGNGATC 2386
Query: 212 HNTLGS-FQCLCPVGQEGPRC 231
G+ CLCP G+ GP C
Sbjct: 2387 VPKSGTDIVCLCPYGRSGPLC 2407
Score = 51.2 bits (121), Expect = 1e-05
Identities = 29/89 (32%), Positives = 38/89 (42%), Gaps = 8/89 (8%)
Query: 964 NCSKELDACQSQPC-----HNHGTCTPKPGGFHCACPPGFVGLRCEGDVDEC---LDQPC 1015
N + + C + PC N GTC +C C G+ G C V C D P
Sbjct: 2601 NAGRSVGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPH 2660
Query: 1016 HPTGTAACHSLANAFYCQCLPGHTGQWCE 1044
H + A C SL + + C C G TG +CE
Sbjct: 2661 HCSRGATCISLPHGYTCFCPLGTTGIYCE 2689
Score = 50.8 bits (120), Expect = 1e-05
Identities = 25/81 (30%), Positives = 40/81 (49%), Gaps = 3/81 (3%)
Query: 431 QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTC 490
++++ C + C + G+C++ + C CP Y+G C+ C + PC G+TC
Sbjct: 2329 KNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATC 2386
Query: 491 LDLLAT-FHCLCPPGLEGQLC 510
+ T CLCP G G LC
Sbjct: 2387 VPKSGTDIVCLCPYGRSGPLC 2407
Score = 50.4 bits (119), Expect = 2e-05
Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 13/91 (14%)
Query: 848 CAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLC 907
CA C N C+ + C C + ++G LC +SC+ ++ C NG C
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQF--ASCE----------NNPCGNGATC 2386
Query: 908 VD-SGPSYFCHCPPGFQGSLCQDHVNPCESR 937
V SG C CP G G LC D +N + R
Sbjct: 2387 VPKSGTDIVCLCPYGRSGPLCTDAINITQPR 2417
Score = 50.1 bits (118), Expect = 2e-05
Identities = 26/85 (30%), Positives = 43/85 (50%), Gaps = 2/85 (2%)
Query: 432 DLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCL 491
++ +C G + C +GG C +F+C C P + G+ C + CL+ C S C+
Sbjct: 2870 NVGDCDGTACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCI 2928
Query: 492 -DLLATFHCLCPPGLEGQLCEVETN 515
D ++ CLC G G+ CE +T+
Sbjct: 2929 PDQSFSYSCLCTLGWVGRYCENKTS 2953
Score = 49.7 bits (117), Expect = 3e-05
Identities = 29/84 (34%), Positives = 38/84 (45%), Gaps = 6/84 (7%)
Query: 555 CRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGA-FFC 613
C C N G C C+C + G CQ C ++PC GA+C+ G C
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPCGNGATCVPKSGTDIVC 2396
Query: 614 LCPSGFTGQLCEVPLCAPNLCQPK 637
LCP G +G LC A N+ QP+
Sbjct: 2397 LCPYGRSGPLC---TDAINITQPR 2417
Score = 49.3 bits (116), Expect = 4e-05
Identities = 25/83 (30%), Positives = 35/83 (42%), Gaps = 12/83 (14%)
Query: 848 CAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLC 907
C C C G +F C CL W G CN +S +++LC + LC
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSC-----------LNNLCLHQSLC 2927
Query: 908 V-DSGPSYFCHCPPGFQGSLCQD 929
+ D SY C C G+ G C++
Sbjct: 2928 IPDQSFSYSCLCTLGWVGRYCEN 2950
Score = 49.3 bits (116), Expect = 4e-05
Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 2/72 (2%)
Query: 934 CESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPG-GFHC 992
C C+NG C + + C+C P + G C++ + +C + C + C P + C
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSC 2937
Query: 993 ACPPGFVGLRCE 1004
C G+VG CE
Sbjct: 2938 LCTLGWVGRYCE 2949
Score = 48.9 bits (115), Expect = 5e-05
Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Query: 770 YCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATC-QDSPQGP 828
+C C N GTC++ C C + G C+ SC ++PC N ATC S
Sbjct: 2338 WCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ---FASCENNPCGNGATCVPKSGTDI 2394
Query: 829 RCLCPTGYTGGSCQTLMDL 847
CLCP G +G C +++
Sbjct: 2395 VCLCPYGRSGPLCTDAINI 2413
Score = 48.5 bits (114), Expect = 6e-05
Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 2/69 (2%)
Query: 901 CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPS-GYLCQCAPG 959
C NGG C +G ++ C C P + G+ C V+ C + C + + C+ S Y C C G
Sbjct: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIPDQSFSYSCLCTLG 2942
Query: 960 YDGQNCSKE 968
+ G+ C +
Sbjct: 2943 WVGRYCENK 2951
Score = 48.1 bits (113), Expect = 8e-05
Identities = 21/60 (35%), Positives = 26/60 (43%), Gaps = 5/60 (8%)
Query: 677 CVCDVGWTGPECEAELGGCISA-----PCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMT 731
C C GW G C + C C+ G TC P GY C CP G TG C + ++
Sbjct: 2634 CNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPHGYTCFCPLGTTGIYCEQALS 2693
Score = 47.8 bits (112), Expect = 1e-04
Identities = 24/76 (31%), Positives = 37/76 (48%), Gaps = 6/76 (7%)
Query: 1010 CLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPL 1069
C C GT C S +C+C ++G+ C+ C + PC +G TC +G+ +
Sbjct: 2339 CAHHLCRNNGT--CISDNENLFCECPRLYSGKLCQFA--SCENNPCGNGATCVPKSGTDI 2394
Query: 1070 GFICHCPKGFEGPTCS 1085
+C CP G GP C+
Sbjct: 2395 --VCLCPYGRSGPLCT 2408
Score = 47.4 bits (111), Expect = 1e-04
Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 5/75 (6%)
Query: 280 CVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTC-QNSAGS 338
C + C+NGG C T++C C W G C++ V C + C + + S
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNL----CLHQSLCIPDQSFS 2934
Query: 339 FHCVCVSGWGGTSCE 353
+ C+C GW G CE
Sbjct: 2935 YSCLCTLGWVGRYCE 2949
Score = 47.0 bits (110), Expect = 2e-04
Identities = 25/79 (31%), Positives = 35/79 (44%), Gaps = 6/79 (7%)
Query: 280 CVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGS- 338
C H C+N GTC + C CP ++G C CE C NG TC +G+
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLC--QFASCENN---PCGNGATCVPKSGTD 2393
Query: 339 FHCVCVSGWGGTSCEENLD 357
C+C G G C + ++
Sbjct: 2394 IVCLCPYGRSGPLCTDAIN 2412
Score = 46.2 bits (108), Expect = 3e-04
Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 7/90 (7%)
Query: 466 GYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNEC-----ASA 520
G + +C A + C C G TC++ + +C C G +G C + C
Sbjct: 2603 GRSVGQCHA--SPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPH 2660
Query: 521 PCLNHADCHDLLNGFQCICLPGFSGTRCEE 550
C A C L +G+ C C G +G CE+
Sbjct: 2661 HCSRGATCISLPHGYTCFCPLGTTGIYCEQ 2690
Score = 46.2 bits (108), Expect = 3e-04
Identities = 30/103 (29%), Positives = 42/103 (40%), Gaps = 4/103 (3%)
Query: 771 CVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATC-QDSPQGPR 829
C C NGG C TFSC C + G C + SC ++ C +++ C D
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV--SCLNNLCLHQSLCIPDQSFSYS 2936
Query: 830 CLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQ 872
CLC G+ G C+ K NS+ P++ LQ
Sbjct: 2937 CLCTLGWVGRYCENKTSFSTAK-FMGNSYIKYIDPNYRMRNLQ 2978
Score = 45.8 bits (107), Expect = 4e-04
Identities = 31/107 (28%), Positives = 42/107 (39%), Gaps = 33/107 (30%)
Query: 624 CEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGW 683
C VP CA +LC+ C + C CP G CQ +SC
Sbjct: 2334 CHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKL------------CQFASCE----- 2376
Query: 684 TGPECEAELGGCISAPCAHGGTCYPQPSGYN--CTCPTGYTGPTCSE 728
+ PC +G TC P+ SG + C CP G +GP C++
Sbjct: 2377 -------------NNPCGNGATCVPK-SGTDIVCLCPYGRSGPLCTD 2409
Score = 45.8 bits (107), Expect = 4e-04
Identities = 24/80 (30%), Positives = 32/80 (40%), Gaps = 5/80 (6%)
Query: 810 CADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQK-----PCPRNSHCLQTGP 864
C+ C N TC +S C C TG+ G C + C + C R + C+
Sbjct: 2614 CSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATCISLPH 2673
Query: 865 SFHCLCLQGWTGPLCNLPLS 884
+ C C G TG C LS
Sbjct: 2674 GYTCFCPLGTTGIYCEQALS 2693
Score = 45.1 bits (105), Expect = 7e-04
Identities = 28/82 (34%), Positives = 38/82 (46%), Gaps = 9/82 (10%)
Query: 354 ENLDDCIAATCAP-----GSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCS 408
+N+++C CA TCI + C CP +G LC C + PC A C
Sbjct: 2329 KNIENCHVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFAS-CENNPCGNGATCV 2387
Query: 409 TNPLTGSTL-CLCQPGYSGPTC 429
P +G+ + CLC G SGP C
Sbjct: 2388 --PKSGTDIVCLCPYGRSGPLC 2407
Score = 44.7 bits (104), Expect = 0.001
Identities = 24/79 (30%), Positives = 31/79 (39%), Gaps = 14/79 (17%)
Query: 160 CSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTL---- 215
C N C NGG C C C P + G+ C + V+ C H +L
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS--------CLNNLCLHQSLCIPD 2930
Query: 216 --GSFQCLCPVGQEGPRCE 232
S+ CLC +G G CE
Sbjct: 2931 QSFSYSCLCTLGWVGRYCE 2949
Score = 44.3 bits (103), Expect = 0.001
Identities = 26/79 (32%), Positives = 38/79 (48%), Gaps = 9/79 (11%)
Query: 396 CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCL-N 454
C C +C+ N T S C C P ++G TC+Q + CL + C H C+ +
Sbjct: 2879 CGYNTCRNGGECTVNGTTFS--CRCLPDWAGNTCNQSV-SCL-----NNLCLHQSLCIPD 2930
Query: 455 TPGSFNCLCPPGYTGSRCE 473
S++CLC G+ G CE
Sbjct: 2931 QSFSYSCLCTLGWVGRYCE 2949
Score = 44.3 bits (103), Expect = 0.001
Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 2/72 (2%)
Query: 700 CAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPG-GYYCTCPPS 758
C +GG C + ++C C + G TC++ + +C + CL+ C P Y C C
Sbjct: 2884 CRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSCLCTLG 2942
Query: 759 HTGPQCQTSTDY 770
G C+ T +
Sbjct: 2943 WVGRYCENKTSF 2954
Score = 43.9 bits (102), Expect = 0.002
Identities = 27/86 (31%), Positives = 33/86 (38%), Gaps = 11/86 (12%)
Query: 1007 VDECLDQPCHPT---GTAACHSLANAFYCQCLPGHTGQWCEVEI---DPCHSQP--CFHG 1058
V +C PC C + YC C G G +C + DP H P C G
Sbjct: 2606 VGQCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
Query: 1059 GTCEATAGSPLGFICHCPKGFEGPTC 1084
TC + P G+ C CP G G C
Sbjct: 2666 ATCISL---PHGYTCFCPLGTTGIYC 2688
Score = 43.1 bits (100), Expect = 0.003
Identities = 21/74 (28%), Positives = 34/74 (45%), Gaps = 2/74 (2%)
Query: 517 CASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQC-QDQPGAFHC 575
C C N +C F C CLP ++G C + + C ++ C + C DQ ++ C
Sbjct: 2879 CGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSV-SCLNNLCLHQSLCIPDQSFSYSC 2937
Query: 576 KCLPGFEGPRCQTE 589
C G+ G C+ +
Sbjct: 2938 LCTLGWVGRYCENK 2951
Score = 42.0 bits (97), Expect = 0.006
Identities = 23/79 (29%), Positives = 32/79 (40%), Gaps = 5/79 (6%)
Query: 802 CEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCL- 860
C+G +C + CRN C + C C + G +C + C C S C+
Sbjct: 2874 CDGT---ACGYNTCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLCIP 2929
Query: 861 QTGPSFHCLCLQGWTGPLC 879
S+ CLC GW G C
Sbjct: 2930 DQSFSYSCLCTLGWVGRYC 2948
Score = 42.0 bits (97), Expect = 0.006
Identities = 20/72 (27%), Positives = 29/72 (40%), Gaps = 2/72 (2%)
Query: 122 CPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYP-QIQC 180
C + C G C + + C C+P W G C C N C++ +C+ C
Sbjct: 2879 CGYNTCRNGGECTVNGTTF-SCRCLPDWAGNTCNQSVSCLNNLCLHQSLCIPDQSFSYSC 2937
Query: 181 HCPPGFEGHACE 192
C G+ G CE
Sbjct: 2938 LCTLGWVGRYCE 2949
Score = 41.6 bits (96), Expect = 0.008
Identities = 26/81 (32%), Positives = 41/81 (50%), Gaps = 9/81 (11%)
Query: 238 CPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTC--QDGL 295
C C N GTC + + ++ F C CP + G C+ +C ++ C NG TC + G
Sbjct: 2339 CAHHLCRNNGTC--ISDNENLF--CECPRLYSGKLCQFA--SCENNPCGNGATCVPKSGT 2392
Query: 296 DTYTCLCPETWTGWDCSEDVD 316
D CLCP +G C++ ++
Sbjct: 2393 D-IVCLCPYGRSGPLCTDAIN 2412
Score = 41.2 bits (95), Expect = 0.010
Identities = 23/92 (25%), Positives = 35/92 (38%), Gaps = 7/92 (7%)
Query: 511 EVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSS-----PCANGGQ 565
+ + C+ C N C + C C G+ G+ C E + C C+ G
Sbjct: 2608 QCHASPCSLMKCGNGGTCIESGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGAT 2667
Query: 566 CQDQPGAFHCKCLPGFEGPRCQTEVDECLSDP 597
C P + C C G G C+ + +SDP
Sbjct: 2668 CISLPHGYTCFCPLGTTGIYCEQALS--ISDP 2697
Score = 41.2 bits (95), Expect = 0.010
Identities = 26/81 (32%), Positives = 34/81 (41%), Gaps = 8/81 (9%)
Query: 349 GTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCS 408
GT+C N TC G C +FSC C P G C+ CL+ C + C
Sbjct: 2876 GTACGYN-------TCRNGGECTVNGTTFSCRCLPDWAGNTCNQSVSCLNNLCLHQSLCI 2928
Query: 409 TNPLTGSTLCLCQPGYSGPTC 429
+ + S CLC G+ G C
Sbjct: 2929 PDQ-SFSYSCLCTLGWVGRYC 2948
Score = 40.0 bits (92), Expect = 0.023
Identities = 23/69 (33%), Positives = 29/69 (42%), Gaps = 5/69 (7%)
Query: 205 CPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLC 264
C +C + + C CP G C+ + C C NG TC K T +CLC
Sbjct: 2344 CRNNGTCISDNENLFCECPRLYSGKLCQFAS--CENNPCGNGATCV---PKSGTDIVCLC 2398
Query: 265 PPGFIGPDC 273
P G GP C
Sbjct: 2399 PYGRSGPLC 2407
Score = 39.7 bits (91), Expect = 0.030
Identities = 28/100 (28%), Positives = 38/100 (38%), Gaps = 7/100 (7%)
Query: 959 GYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPT 1018
G + +NC + C C N+GTC C CP + G C+ C + PC
Sbjct: 2328 GKNIENC--HVPWCAHHLCRNNGTCISDNENLFCECPRLYSGKLCQ--FASCENNPC-GN 2382
Query: 1019 GTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHG 1058
G C C G +G C I+ +QP F G
Sbjct: 2383 GATCVPKSGTDIVCLCPYGRSGPLCTDAIN--ITQPRFSG 2420
Score = 39.3 bits (90), Expect = 0.039
Identities = 23/76 (30%), Positives = 31/76 (40%), Gaps = 3/76 (3%)
Query: 479 CLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLL-NGFQC 537
C C TC+ C CP G+LC+ + C + PC N A C C
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFAS--CENNPCGNGATCVPKSGTDIVC 2396
Query: 538 ICLPGFSGTRCEEDID 553
+C G SG C + I+
Sbjct: 2397 LCPYGRSGPLCTDAIN 2412
Score = 38.9 bits (89), Expect = 0.051
Identities = 20/66 (30%), Positives = 27/66 (40%), Gaps = 1/66 (1%)
Query: 593 CLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQK-DKANCLC 651
C C +C+ FC CP ++G+LC+ C N C C + CLC
Sbjct: 2339 CAHHLCRNNGTCISDNENLFCECPRLYSGKLCQFASCENNPCGNGATCVPKSGTDIVCLC 2398
Query: 652 PDGSPG 657
P G G
Sbjct: 2399 PYGRSG 2404
Score = 38.1 bits (87), Expect = 0.087
Identities = 27/93 (29%), Positives = 39/93 (41%), Gaps = 17/93 (18%)
Query: 25 GLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALL 84
G CG C NGG C +++ +C+C P + G TC C N LC + C
Sbjct: 2876 GTACGY--NTCRNGGEC-TVNGTTFSCRCLPDWAGNTCNQSVSCLN-NLCLHQSLC---- 2927
Query: 85 PAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAK 117
+P + S+ C C G+ G C+ K
Sbjct: 2928 -----IPDQ----SFSYSCLCTLGWVGRYCENK 2951
Score = 37.7 bits (86), Expect = 0.11
Identities = 68/335 (20%), Positives = 106/335 (31%), Gaps = 66/335 (19%)
Query: 884 SSCQKAALSQGIDVSSLCHNGGLC----VDSG-PSYFCHCPPGFQGSLCQDHVNPCESRP 938
+S + + + +CHNGG C + SG S+ C CP F G C+ P
Sbjct: 2091 TSVSPSVAAPSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFF--P 2148
Query: 939 CQNGATCMAQP---------------------SGYLCQCAPGYDGQNCSKE---LDACQS 974
NG + + P + L +G NC K+ L +
Sbjct: 2149 SFNGNSYLELPFLKFVLEKEHNRTVTIYLTIKTNSLNGTILYSNGNNCGKQFLHLFLVEG 2208
Query: 975 QPCHNHG-----------------TCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHP 1017
+P +G T P P G G+ C ++ P
Sbjct: 2209 RPSVKYGCGNSQNILTVSANYSINTNAFTPITIRYTTPVGSPGVVCMIEMTADGKPPVQK 2268
Query: 1018 TGTAACHSLANAFYCQCLPGHTGQWCEV--EIDPCHSQPCFHGGTCEATAGSPLGFICHC 1075
T H+ + A++ GH ++ + P + F G + + FI
Sbjct: 2269 KDTEISHA-SQAYFESMFLGHIPANVQIHKKAGPVYG---FRGCILDLQVNNKEFFIIDE 2324
Query: 1076 PKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCG 1135
+ + H P C H C + G C+ + F C C Y G C
Sbjct: 2325 ARHGKNIENCH-VPWCAHHLCRNNGTCISDNENLF---CECPRLYSGKLCQFASCEN--- 2377
Query: 1136 PPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRC 1170
+PC +C +G C CP+ GP C
Sbjct: 2378 --NPCGNGATCVPKSGTD---IVCLCPYGRSGPLC 2407
Score = 36.2 bits (82), Expect = 0.33
Identities = 24/89 (26%), Positives = 34/89 (38%), Gaps = 10/89 (11%)
Query: 1086 HRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCL--TPPAPKGCGPPSPCLYN 1143
H +P C C +GG C+ S G C C +G+ G C PP C
Sbjct: 2610 HASP-CSLMKCGNGGTCIES---GTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRG 2665
Query: 1144 GSCSETTGLGGPGFRCSCPHSSPGPRCQK 1172
+C G+ C CP + G C++
Sbjct: 2666 ATCISLPH----GYTCFCPLGTTGIYCEQ 2690
Score = 35.8 bits (81), Expect = 0.43
Identities = 17/45 (37%), Positives = 20/45 (44%), Gaps = 5/45 (11%)
Query: 160 CSANPCVNGGVCLATY-----PQIQCHCPPGFEGHACERDVNECF 199
C + C NGG C A + QC CP F G CE+D F
Sbjct: 2103 CQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKDAGLFF 2147
Score = 35.0 bits (79), Expect = 0.74
Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 5/43 (11%)
Query: 277 PDNCVSHQCQNGGTC-----QDGLDTYTCLCPETWTGWDCSED 314
P C C NGGTC G+ ++ C CP +TG C +D
Sbjct: 2100 PSVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCEKD 2142
Score = 34.7 bits (78), Expect = 0.96
Identities = 23/85 (27%), Positives = 30/85 (35%), Gaps = 7/85 (8%)
Query: 1005 GDVD--ECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCE 1062
GD D C C G C F C+CLP G C + C + C H C
Sbjct: 2872 GDCDGTACGYNTCRNGGE--CTVNGTTFSCRCLPDWAGNTCNQSVS-CLNNLCLHQSLC- 2927
Query: 1063 ATAGSPLGFICHCPKGFEGPTCSHR 1087
+ C C G+ G C ++
Sbjct: 2928 -IPDQSFSYSCLCTLGWVGRYCENK 2951
Score = 33.5 bits (75), Expect = 2.1
Identities = 37/126 (29%), Positives = 46/126 (36%), Gaps = 37/126 (29%)
Query: 35 CANGGTCLSLSLGQGT---CQCAPGFLG----ETCQFPDPCQN-AQLCQNGGSCQALLPA 86
C NGGTC+ GT C C G+ G ET DP + C G +C
Sbjct: 2619 CGNGGTCIE----SGTSVYCNCTTGWKGSFCTETVSTCDPEHDPPHHCSRGATC------ 2668
Query: 87 PLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPP---------SFCS--KRGRCHI 135
+ LP + C C G TG C+ L P SF S R + HI
Sbjct: 2669 -ISLPH-------GYTCFCPLGTTGIYCEQALSISDPSFRSNELSWMSFASFHVRKKTHI 2720
Query: 136 QASGRP 141
Q +P
Sbjct: 2721 QLQFQP 2726
Score = 33.1 bits (74), Expect = 2.8
Identities = 20/61 (32%), Positives = 28/61 (45%), Gaps = 7/61 (11%)
Query: 731 TACHSGPCLNGGSCNP---SPG--GYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNR 785
+ C C NGG+C+ S G + C CP TG C+ D + P FNG + +
Sbjct: 2101 SVCQQDVCHNGGTCHAIFLSSGIVSFQCDCPLHFTGRFCE--KDAGLFFPSFNGNSYLEL 2158
Query: 786 P 786
P
Sbjct: 2159 P 2159
>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
Length = 1238
Score = 462 bits (1189), Expect = e-129
Identities = 271/831 (32%), Positives = 364/831 (43%), Gaps = 90/831 (10%)
Query: 264 CPPGFIGPDCE--VNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQ 321
C G++G +C+ V C +GG G C C W G C DEC
Sbjct: 231 CMDGWMGKECKEAVCKQGC---NLLHGGCTVPG----ECRCSYGWQGRFC----DECVPY 279
Query: 322 GPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAA-TCAPGSTCID-RVGSFSC 379
P C +G + + C C + WGG C+++L+ C + C G TCI+ + C
Sbjct: 280 --PGCVHGSCVE----PWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRC 333
Query: 380 LCPPGRTGLLCH-LEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLM 438
CP G +G C E C S PC C P C C G+SGPTC D+DEC
Sbjct: 334 TCPDGYSGRNCEKAEHACTSNPCANGGSCHEVP--SGFECHCPSGWSGPTCALDIDEC-- 389
Query: 439 AQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFH 498
+PC GG+C++ F C+CP + G+ C+ D NEC +PC +C +L+ ++
Sbjct: 390 ---ASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYY 446
Query: 499 CLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSS 558
C C PG +G C + N+C C + C DL+NG+QC+C GF G CE + DEC SS
Sbjct: 447 CDCIPGWKGINCHINVNDCRGQ-CQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASS 505
Query: 559 PCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSG 618
PC +GG C+D FHC C GF GP C+ +VD C PC GA C +L G ++C CP
Sbjct: 506 PCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDD 565
Query: 619 FTGQLCEVPL--CAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCH-HGHCQRS 675
F G+ C VP C C+ C D PG + C HG C
Sbjct: 566 FGGKNCSVPREPCPGGACRVIDGCGS----------DAGPGMPGTAASGVCGPHGRCVSQ 615
Query: 676 -----SCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEM 730
SC+CD G+TG C + C+ PC +GGTC + + C CP+G+ G C
Sbjct: 616 PGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNP 675
Query: 731 TACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFS 790
C PC + G C +YC C G C + C + C NGGTC + TF
Sbjct: 676 NDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFR 735
Query: 791 CLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQ 850
C C G++G C SC +PC N TC S C+C G+ G +C + C
Sbjct: 736 CACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNP 795
Query: 851 KPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDS 910
PC C+ F C C G+ GP C + + CQ SS C G CVD
Sbjct: 796 LPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQ----------SSPCAYGATCVDE 845
Query: 911 GPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYL-----CQCAPGYDGQNC 965
Y C CPPG G CQ+ + R C + T S ++ C+C G ++C
Sbjct: 846 INGYRCSCPPGRAGPRCQEVIG--FGRSCWSRGTPFPHGSSWVEDCNSCRCLDG--RRDC 901
Query: 966 SKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRC-EGDVDECLDQPCHPTGTAACH 1024
SK C +PC G +P CP +G RC E +CL PC G
Sbjct: 902 SKVW--CGWKPCLLAG----QPEALSAQCP---LGQRCLEKAPGQCLRPPCEAWGECGAE 952
Query: 1025 SLANAFYCQCLP--GHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFIC 1073
+ CLP GH C ++ H G+ +G IC
Sbjct: 953 EPPST---PCLPRSGHLDNNC--------ARLTLHFNRDHVPQGTTVGAIC 992
Score = 437 bits (1123), Expect = e-122
Identities = 252/782 (32%), Positives = 343/782 (43%), Gaps = 81/782 (10%)
Query: 105 CLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSANP 164
C+ G+ G+ C+ E C G C + +C C GW G C D C P
Sbjct: 231 CMDGWMGKECK---EAVCKQGCNLLHGGCTVPG----ECRCSYGWQGRFC---DECVPYP 280
Query: 165 -CVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTL-GSFQCLC 222
CV+G C+ + QC+C + G C++D+N C PC G +C N ++C C
Sbjct: 281 GCVHGS-CVEPW---QCNCETNWGGLLCDKDLNYCGSHH-PCTNGGTCINAEPDQYRCTC 335
Query: 223 PVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVS 282
P G G CE C C+NGG+C +P S F C CP G+ GP C ++ D C S
Sbjct: 336 PDGYSGRNCEKAEHACTSNPCANGGSCHEVP---SGFE-CHCPSGWSGPTCALDIDECAS 391
Query: 283 HQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCV 342
+ C GGTC D +D + C+CPE W G C D +ECE G P C N +C+N G ++C
Sbjct: 392 NPCAAGGTCVDQVDGFECICPEQWVGATCQLDANECE--GKP-CLNAFSCKNLIGGYYCD 448
Query: 343 CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DMCLSQPC 401
C+ GW G +C N++DC C G TC D V + C+CP G G C LE D C S PC
Sbjct: 449 CIPGWKGINCHINVNDC-RGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPC 507
Query: 402 HGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNC 461
H C L C C G+SGP C D+D C PSPC +G C N G + C
Sbjct: 508 HSGGLC--EDLADGFHCHCPQGFSGPLCEVDVDLC-----EPSPCRNGARCYNLEGDYYC 560
Query: 462 LCPPGYTGSRCEADHNEC-----------------------LSQPCHPGSTCLDLL-ATF 497
CP + G C C S C P C+ F
Sbjct: 561 ACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNF 620
Query: 498 HCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRS 557
C+C G G C ++C PC N C D ++ F+C C G+ G C+ + ++C
Sbjct: 621 SCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLP 680
Query: 558 SPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPS 617
PC + G+C D F+C C G++G C + +C + C G +C D F C CP
Sbjct: 681 DPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPP 740
Query: 618 GFTGQLCEV---PLCAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPEDNCT---CHH 669
G+ G C V C PN C C +C+C DG G C ++C C++
Sbjct: 741 GWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYN 800
Query: 670 G-----HCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGP 724
G C C G+ GP+C + C S+PCA+G TC + +GY C+CP G GP
Sbjct: 801 GGICVDGVNWFRCECAPGFAGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGP 860
Query: 725 TCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSH-TGPQCQTSTDYCVSAPCFNGGTCV 783
C E + S C + G+ P + C + S +C PC G
Sbjct: 861 RCQEVIGFGRS--CWSRGTPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAG--- 915
Query: 784 NRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATC-QDSPQGPRCLCPTGYTGGSCQ 842
+P S C + G RC K C PC C + P CL +G+ +C
Sbjct: 916 -QPEALSAQCPL---GQRCLEKAPGQCLRPPCEAWGECGAEEPPSTPCLPRSGHLDNNCA 971
Query: 843 TL 844
L
Sbjct: 972 RL 973
Score = 417 bits (1071), Expect = e-116
Identities = 244/687 (35%), Positives = 317/687 (46%), Gaps = 75/687 (10%)
Query: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAP 87
CGS PC NGGTC++ Q C C G+ G C+ + + C NGGSC
Sbjct: 311 CGSH-HPCTNGGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHE----- 364
Query: 88 LGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMP 147
+PS F C C G++G C + D C + C+ G C Q G +C C
Sbjct: 365 --VPS-------GFECHCPSGWSGPTCALDI-DECASNPCAAGGTCVDQVDGF-ECICPE 413
Query: 148 GWTGEQCQL-RDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCP 206
W G CQL + C PC+N C C C PG++G C +VN+C G C
Sbjct: 414 QWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKGINCHINVNDC---RGQCQ 470
Query: 207 KGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPP 266
G +C + + +QC+CP G G CEL C C +GG C+ + + FH C CP
Sbjct: 471 HGGTCKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLAD---GFH-CHCPQ 526
Query: 267 GFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCS-----------EDV 315
GF GP CEV+ D C C+NG C + Y C CP+ + G +CS +
Sbjct: 527 GFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVI 586
Query: 316 DECETQ---GPPHCRNGGTC-------QNSAGSFHCVCVSGWGGTSCEENLDDCIAATCA 365
D C + G P G C G+F C+C SG+ GT C EN+DDC+ C
Sbjct: 587 DGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCR 646
Query: 366 PGSTCIDRVGSFSCLCPPGRTGLLCHLE-DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGY 424
G TCID V +F C CP G G LC + CL PCH +C L C C G+
Sbjct: 647 NGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRC--YDLVNDFYCACDDGW 704
Query: 425 SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCE-ADHNECLSQP 483
G TCH +C C +GG+C ++ +F C CPPG+ GS C A ++ CL P
Sbjct: 705 KGKTCHSREFQC-----DAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNP 759
Query: 484 CHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGF 543
C G TC+ A+F C+C G EG+ C TN+C PC N C D +N F+C C PGF
Sbjct: 760 CVNGGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGF 819
Query: 544 SGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVD---ECLS--DPC 598
+G C +IDEC+SSPCA G C D+ + C C PG GPRCQ + C S P
Sbjct: 820 AGPDCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPF 879
Query: 599 PVGASCLDLPGAFFCL-----CPSGFTG----QLCEVPLCAPNLCQPKQICKDQKDKANC 649
P G+S ++ + CL C + G L P C Q C +K C
Sbjct: 880 PHGSSWVEDCNSCRCLDGRRDCSKVWCGWKPCLLAGQPEALSAQCPLGQRCL-EKAPGQC 938
Query: 650 LCPD----GSPGC-APPEDNCTCHHGH 671
L P G G PP C GH
Sbjct: 939 LRPPCEAWGECGAEEPPSTPCLPRSGH 965
Score = 410 bits (1055), Expect = e-114
Identities = 258/795 (32%), Positives = 346/795 (43%), Gaps = 102/795 (12%)
Query: 539 CLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPC 598
C+ G+ G C+E + C+ G C PG C+C G++G C DEC+ P
Sbjct: 231 CMDGWMGKECKEAV--CKQGCNLLHGGCT-VPG--ECRCSYGWQGRFC----DECVPYPG 281
Query: 599 PVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKD-------QKDKANCLC 651
V SC++ + C C + + G LC+ L N C C + + D+ C C
Sbjct: 282 CVHGSCVE---PWQCNCETNWGGLLCDKDL---NYCGSHHPCTNGGTCINAEPDQYRCTC 335
Query: 652 PDGSPG--CAPPEDNCT----CHHGHCQRS----SCVCDVGWTGPECEAELGGCISAPCA 701
PDG G C E CT + G C C C GW+GP C ++ C S PCA
Sbjct: 336 PDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCA 395
Query: 702 HGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTG 761
GGTC Q G+ C CP + G TC + C PCLN SC GGYYC C P G
Sbjct: 396 AGGTCVDQVDGFECICPEQWVGATCQLDANECEGKPCLNAFSCKNLIGGYYCDCIPGWKG 455
Query: 762 PQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATC 821
C + + C C +GGTC + + C+C GF G CE + R CA SPC + C
Sbjct: 456 INCHINVNDC-RGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELE-RDECASSPCHSGGLC 513
Query: 822 QDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNL 881
+D G C CP G++G C+ +DLC PC + C ++C C + G C++
Sbjct: 514 EDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSV 573
Query: 882 PLSSCQKAALS-------------QGIDVSSLCHNGGLCVDS-GPSYFCHCPPGFQGSLC 927
P C A G S +C G CV G ++ C C GF G+ C
Sbjct: 574 PREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYC 633
Query: 928 QDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKP 987
++++ C +PC+NG TC+ + + C C G++G+ C + C PCH+ G C
Sbjct: 634 HENIDDCLGQPCRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLV 693
Query: 988 GGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEV-E 1046
F+CAC G+ G C +C C GT C+ + F C C PG G C V +
Sbjct: 694 NDFYCACDDGWKGKTCHSREFQCDAYTCSNGGT--CYDSGDTFRCACPPGWKGSTCAVAK 751
Query: 1047 IDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSP 1106
C PC +GGTC GS F C C G+EG TC+H C C++GG+C+
Sbjct: 752 NSSCLPNPCVNGGTC---VGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGV 808
Query: 1107 KPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSP 1166
RC C G+ GPDC C SPC Y +C + G+RCSCP
Sbjct: 809 NWF---RCECAPGFAGPDCRI--NIDEC-QSSPCAYGATCVDEIN----GYRCSCPPGRA 858
Query: 1167 GPRCQK----------PGAKGCEGRSGDGACDA--------GCSGPGGNWDGGDCSL-GV 1207
GPRCQ+ G G S C++ CS W C L G
Sbjct: 859 GPRCQEVIGFGRSCWSRGTPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWK--PCLLAGQ 916
Query: 1208 PDPWKG-CPSHSRCWLLFRDGQC-HPQCDS-EECLFDGYDCETPPA--CTPA---YDQYC 1259
P+ CP RC L GQC P C++ EC E PP+ C P D C
Sbjct: 917 PEALSAQCPLGQRC-LEKAPGQCLRPPCEAWGEC-----GAEEPPSTPCLPRSGHLDNNC 970
Query: 1260 HD---HFHNGHCEKG 1271
HF+ H +G
Sbjct: 971 ARLTLHFNRDHVPQG 985
Score = 124 bits (312), Expect = 7e-28
Identities = 112/392 (28%), Positives = 148/392 (37%), Gaps = 54/392 (13%)
Query: 918 CPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPC 977
C G+ G C++ V G T + C+C+ G+ G+ C D C P
Sbjct: 231 CMDGWMGKECKEAVCKQGCNLLHGGCTVPGE-----CRCSYGWQGRFC----DECVPYPG 281
Query: 978 HNHGTCTPKPGGFHCACPPGFVGLRCEGDVDEC-LDQPCHPTGTAACHSLANAFYCQCLP 1036
HG+C + C C + GL C+ D++ C PC GT ++ + + C C
Sbjct: 282 CVHGSCVEP---WQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCI-NAEPDQYRCTCPD 337
Query: 1037 GHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHC 1096
G++G+ CE C S PC +GG+C P GF CHCP G+ GPTC+ C + C
Sbjct: 338 GYSGRNCEKAEHACTSNPCANGGSCHEV---PSGFECHCPSGWSGPTCALDIDECASNPC 394
Query: 1097 HHGGLCLPSPKPGFPPRCACLSGYGGPDC-LTPPAPKGCGPPSPCLYNGSCSETTGLGGP 1155
GG C+ GF C C + G C L +G PCL SC G
Sbjct: 395 AAGGTCV-DQVDGF--ECICPEQWVGATCQLDANECEG----KPCLNAFSCKNLIG---- 443
Query: 1156 GFRCSCPHSSPGPRCQKPGAKGCEGRSGDGAC------DAGCSGPGGNWDGGDCSLGVPD 1209
G+ C C G C C G+ G C P G + G C L D
Sbjct: 444 GYYCDCIPGWKGINCH-INVNDCRGQCQHGGTCKDLVNGYQCVCPRG-FGGRHCEL-ERD 500
Query: 1210 PWKGCPSHS--RCWLLFRDGQCH-------PQCDSEECLFDGYDCETPPACTPAYDQY-- 1258
P HS C L CH P C+ + L + C C Y
Sbjct: 501 ECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCEVDVDLCEPSPCRNGARCYNLEGDYYC 560
Query: 1259 -CHDHFHNGHCEKGCNTAECGWDGGDCRPEDG 1289
C D F K C+ GG CR DG
Sbjct: 561 ACPDDFGG----KNCSVPREPCPGGACRVIDG 588
Score = 40.8 bits (94), Expect = 0.013
Identities = 52/212 (24%), Positives = 74/212 (34%), Gaps = 37/212 (17%)
Query: 1115 ACLSGYGGPDCLTPPAPKGCG-PPSPCLYNGSCSETTGLGG---------PGFRCSCPHS 1164
AC+ G+ G +C +GC C G C + G G PG C H
Sbjct: 230 ACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPYPG----CVHG 285
Query: 1165 SPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGN---WDGGDCSLGVPDPWK-GCP---SH 1217
S C +P CE G CD + G + +GG C PD ++ CP S
Sbjct: 286 S----CVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSG 341
Query: 1218 SRCWLLFRDGQCHPQCDSEEC--LFDGYDCETP-----PACTPAYDQYCHDH-FHNGHCE 1269
C +P + C + G++C P P C D+ + G C
Sbjct: 342 RNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCAAGGTCV 401
Query: 1270 KGCNTAEC----GWDGGDCRPEDGDPEWGPSL 1297
+ EC W G C+ + + E P L
Sbjct: 402 DQVDGFECICPEQWVGATCQLDANECEGKPCL 433
>gi|4557679 jagged 1 precursor [Homo sapiens]
Length = 1218
Score = 449 bits (1154), Expect = e-125
Identities = 254/819 (31%), Positives = 351/819 (42%), Gaps = 109/819 (13%)
Query: 104 TCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSAN 163
TC+ G+ G C + C K G C + C C GW G C D C +
Sbjct: 219 TCMEGWMGPECNRAI---CRQGCSPKHGSCKLPGD----CRCQYGWQGLYC---DKCIPH 268
Query: 164 PCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNT-LGSFQCLC 222
P G+C + QC C + G C++D+N C PC G +C NT +QC C
Sbjct: 269 PGCVHGICNEPW---QCLCETNWGGQLCDKDLNYCGTHQ-PCLNGGTCSNTGPDKYQCSC 324
Query: 223 PVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVS 282
P G GP CE+ C C N G+C+ + S C C PG+ GP C N D+C
Sbjct: 325 PEGYSGPNCEIAEHACLSDPCHNRGSCK----ETSLGFECECSPGWTGPTCSTNIDDCSP 380
Query: 283 HQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCV 342
+ C +GGTCQD ++ + C+CP WTG C D +ECE + C N +C+N S++C
Sbjct: 381 NNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAK---PCVNAKSCKNLIASYYCD 437
Query: 343 CVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DMCLSQPC 401
C+ GW G +C+ N++DC+ C ++C D V + C+CPPG G C + D C S PC
Sbjct: 438 CLPGWMGQNCDININDCL-GQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPC 496
Query: 402 HGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNC 461
C CLC G+SG C D+D C P+PC++G C N + C
Sbjct: 497 LNGGHCQNE--INRFQCLCPTGFSGNLCQLDIDYC-----EPNPCQNGAQCYNRASDYFC 549
Query: 462 LCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLAT------------------------- 496
CP Y G C + C + PC +C +A+
Sbjct: 550 KCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQS 609
Query: 497 ---FHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDID 553
F C C G G C N+C S PC N C D +N ++CIC G+ G CE +I+
Sbjct: 610 GGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNIN 669
Query: 554 ECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFC 613
+C +PC NGG C+D F+C C G++G C + +C C G +C D AF C
Sbjct: 670 DCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKC 729
Query: 614 LCPSGFTGQLCEV---PLCAPNLCQPKQICKDQKDKANCLCPDG--SPGCAPPEDNCTCH 668
+CP G+ G C + C PN C C + C+C +G P CA ++C+ H
Sbjct: 730 MCPGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPH 789
Query: 669 ----HGHCQRSS----CVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTG 720
G C C C G+ GP+C + C S+PCA G TC + +GY C CP G
Sbjct: 790 PCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPG 849
Query: 721 YTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGG 780
++G C E PC+ GS P + D C + C NG
Sbjct: 850 HSGAKCQE----VSGRPCITMGSVIPDGAKW----------------DDDCNTCQCLNGR 889
Query: 781 TCVNRP--GTFSCLCAMGF----QGPRCEGKLRPSCADSPCRNRATCQDS---PQGPRCL 831
++ G CL G G C L C PC C+ S P +C
Sbjct: 890 IACSKVWCGPRPCLLHKGHSECPSGQSCIPILDDQCFVHPCTGVGECRSSSLQPVKTKCT 949
Query: 832 CPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLC 870
+ Y D CA N + G + +C
Sbjct: 950 SDSYY--------QDNCANITFTFNKEMMSPGLTTEHIC 980
Score = 433 bits (1113), Expect = e-121
Identities = 235/727 (32%), Positives = 331/727 (45%), Gaps = 100/727 (13%)
Query: 418 CLCQPGYSGPTCHQDLDECLMAQQGPSP-CEHGGSCLNTPGSFNCLCPPGYTGSRCEADH 476
C CQ G+ G C D+C+ P P C HG N P + CLC + G C+ D
Sbjct: 251 CRCQYGWQGLYC----DKCI-----PHPGCVHG--ICNEP--WQCLCETNWGGQLCDKDL 297
Query: 477 NEC-LSQPCHPGSTCLDLLAT-FHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNG 534
N C QPC G TC + + C CP G G CE+ + C S PC N C + G
Sbjct: 298 NYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLG 357
Query: 535 FQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECL 594
F+C C PG++G C +ID+C + C++GG CQD F C C P + G CQ + +EC
Sbjct: 358 FECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECE 417
Query: 595 SDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPL--CAPNLCQPKQICKDQKDKANCLCP 652
+ PC SC +L +++C C G+ GQ C++ + C CQ C+D + C+CP
Sbjct: 418 AKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCLGQ-CQNDASCRDLVNGYRCICP 476
Query: 653 DGSPG--CAPPEDNCTCHH----GHCQ----RSSCVCDVGWTGPECEAELGGCISAPCAH 702
G G C D C + GHCQ R C+C G++G C+ ++ C PC +
Sbjct: 477 PGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQN 536
Query: 703 GGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPC---------------------LNG 741
G CY + S Y C CP Y G CS C + PC ++
Sbjct: 537 GAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISS 596
Query: 742 GSCNP-------SPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCA 794
C P S G + C C TG C + + C S PC NGGTC++ ++ C+C+
Sbjct: 597 NVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICS 656
Query: 795 MGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCP 854
G++G CE + C+ +PC N TC+D C C G+ G +C + C + C
Sbjct: 657 DGWEGAYCETNIN-DCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCN 715
Query: 855 RNSHCLQTGPSFHCLCLQGWTGPLCNLPL-SSCQKAALSQGIDVSSLCHNGGLCVDSGPS 913
C G +F C+C GW G CN+ SSC + + CHNGG CV +G S
Sbjct: 716 NGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSC----------LPNPCHNGGTCVVNGES 765
Query: 914 YFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQ 973
+ C C G++G +C + N C PC N TC+ + Y C+CAPG+ G +C ++ CQ
Sbjct: 766 FTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGPDCRININECQ 825
Query: 974 SQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLA---NAF 1030
S PC TC + G+ C CPPG G +C+ E +PC G+ +
Sbjct: 826 SSPCAFGATCVDEINGYRCVCPPGHSGAKCQ----EVSGRPCITMGSVIPDGAKWDDDCN 881
Query: 1031 YCQCLPGH-----------------------TGQWC-EVEIDPCHSQPCFHGGTCEATAG 1066
CQCL G +GQ C + D C PC G C +++
Sbjct: 882 TCQCLNGRIACSKVWCGPRPCLLHKGHSECPSGQSCIPILDDQCFVHPCTGVGECRSSSL 941
Query: 1067 SPLGFIC 1073
P+ C
Sbjct: 942 QPVKTKC 948
Score = 429 bits (1104), Expect = e-119
Identities = 246/777 (31%), Positives = 335/777 (43%), Gaps = 111/777 (14%)
Query: 302 CPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFH----CVCVSGWGGTSCEENLD 357
C E W G +C+ + CR G C GS C C GW G C++
Sbjct: 220 CMEGWMGPECNRAI----------CRQG--CSPKHGSCKLPGDCRCQYGWQGLYCDK--- 264
Query: 358 DCIAATCAPGSTCIDRVGS--FSCLCPPGRTGLLCHLE-DMC-LSQPCHGDAQCSTNPLT 413
C P C+ + + + CLC G LC + + C QPC CS N
Sbjct: 265 ------CIPHPGCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCS-NTGP 317
Query: 414 GSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCE 473
C C GYSGP C CL PC + GSC T F C C PG+TG C
Sbjct: 318 DKYQCSCPEGYSGPNCEIAEHACLS-----DPCHNRGSCKETSLGFECECSPGWTGPTCS 372
Query: 474 ADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLN 533
+ ++C C G TC DL+ F C+CPP G+ C+++ NEC + PC+N C +L+
Sbjct: 373 TNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIA 432
Query: 534 GFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDEC 593
+ C CLPG+ G C+ +I++C C N C+D + C C PG+ G C+ ++DEC
Sbjct: 433 SYYCDCLPGWMGQNCDININDCLGQ-CQNDASCRDLVNGYRCICPPGYAGDHCERDIDEC 491
Query: 594 LSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPL--CAPNLCQPKQICKDQKDKANCLC 651
S+PC G C + F CLCP+GF+G LC++ + C PN CQ C ++ C C
Sbjct: 492 ASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKC 551
Query: 652 PDGSPG--CAPPEDNCT---CH----------------------------HGHCQRSS-- 676
P+ G C+ +D+C C HG C+ S
Sbjct: 552 PEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGG 611
Query: 677 ---CVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTAC 733
C C+ G+TG C + C S PC +GGTC + Y C C G+ G C + C
Sbjct: 612 KFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDC 671
Query: 734 HSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLC 793
PC NGG+C +YC C G C + C A C NGGTC + F C+C
Sbjct: 672 SQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMC 731
Query: 794 AMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPC 853
G++G C SC +PC N TC + + C+C G+ G C + C+ PC
Sbjct: 732 PGGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPC 791
Query: 854 PRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPS 913
+ C+ + C C G+ GP C + ++ CQ SS C G CVD
Sbjct: 792 YNSGTCVDGDNWYRCECAPGFAGPDCRININECQ----------SSPCAFGATCVDEING 841
Query: 914 YFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGY-----LCQCAPGYDGQNCSKE 968
Y C CPPG G+ CQ+ RPC + + + + CQC G CSK
Sbjct: 842 YRCVCPPGHSGAKCQE----VSGRPCITMGSVIPDGAKWDDDCNTCQCLNGRIA--CSKV 895
Query: 969 LDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHS 1025
C +PC H H CP G + D+C PC TG C S
Sbjct: 896 W--CGPRPCLLHKG--------HSECPSGQSCIPILD--DQCFVHPC--TGVGECRS 938
Score = 417 bits (1072), Expect = e-116
Identities = 235/688 (34%), Positives = 313/688 (45%), Gaps = 86/688 (12%)
Query: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAP 87
CG+ +PC NGGTC + + C C G+ G C+ + + C N GSC+
Sbjct: 300 CGTH-QPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCK---ETS 355
Query: 88 LGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMP 147
LG F C C PG+TG C ++D C P+ CS G C +G +C C P
Sbjct: 356 LG-----------FECECSPGWTGPTCSTNIDD-CSPNNCSHGGTCQDLVNGF-KCVCPP 402
Query: 148 GWTGEQCQL-RDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCP 206
WTG+ CQL + C A PCVN C C C PG+ G C+ ++N+C G C
Sbjct: 403 QWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMGQNCDININDCL---GQCQ 459
Query: 207 KGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPP 266
SC + + ++C+CP G G CE C C NGG CQ + CLCP
Sbjct: 460 NDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQ----NEINRFQCLCPT 515
Query: 267 GFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECET------ 320
GF G C+++ D C + CQNG C + Y C CPE + G +CS D C T
Sbjct: 516 GFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVI 575
Query: 321 -------------QGPPH-----CRNGGTCQN-SAGSFHCVCVSGWGGTSCEENLDDCIA 361
+G + C G C++ S G F C C G+ GT C EN++DC +
Sbjct: 576 DSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCES 635
Query: 362 ATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DMCLSQPCHGDAQCSTNPLTGSTLCLC 420
C G TCID V S+ C+C G G C + C PCH C L C C
Sbjct: 636 NPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTC--RDLVNDFYCDC 693
Query: 421 QPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCE-ADHNEC 479
+ G+ G TCH +C + C +GG+C + +F C+CP G+ G+ C A ++ C
Sbjct: 694 KNGWKGKTCHSRDSQC-----DEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSC 748
Query: 480 LSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCIC 539
L PCH G TC+ +F C+C G EG +C TN+C+ PC N C D N ++C C
Sbjct: 749 LPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCYNSGTCVDGDNWYRCEC 808
Query: 540 LPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPC- 598
PGF+G C +I+EC+SSPCA G C D+ + C C PG G +CQ E PC
Sbjct: 809 APGFAGPDCRININECQSSPCAFGATCVDEINGYRCVCPPGHSGAKCQ----EVSGRPCI 864
Query: 599 ------PVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCP 652
P GA D C C +G C C P C K + CP
Sbjct: 865 TMGSVIPDGAKWDD--DCNTCQCLNGRIA--CSKVWCGPRPC--------LLHKGHSECP 912
Query: 653 DGSPGCAPPEDNCTCHH----GHCQRSS 676
G +D C H G C+ SS
Sbjct: 913 SGQSCIPILDDQCFVHPCTGVGECRSSS 940
Score = 406 bits (1043), Expect = e-112
Identities = 241/763 (31%), Positives = 336/763 (44%), Gaps = 93/763 (12%)
Query: 539 CLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPC 598
C+ G+ G C I CR G C+ PG C+C G++G C D+C+ P
Sbjct: 220 CMEGWMGPECNRAI--CRQGCSPKHGSCK-LPG--DCRCQYGWQGLYC----DKCIPHPG 270
Query: 599 PVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQ-------KDKANCLC 651
V C + + CLC + + GQLC+ L N C Q C + DK C C
Sbjct: 271 CVHGICNE---PWQCLCETNWGGQLCDKDL---NYCGTHQPCLNGGTCSNTGPDKYQCSC 324
Query: 652 PDG--SPGCAPPEDNCT---CHH-GHCQRSS----CVCDVGWTGPECEAELGGCISAPCA 701
P+G P C E C CH+ G C+ +S C C GWTGP C + C C+
Sbjct: 325 PEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCS 384
Query: 702 HGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTG 761
HGGTC +G+ C CP +TG TC + C + PC+N SC YYC C P G
Sbjct: 385 HGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMG 444
Query: 762 PQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATC 821
C + + C+ C N +C + + C+C G+ G CE + CA +PC N C
Sbjct: 445 QNCDININDCLGQ-CQNDASCRDLVNGYRCICPPGYAGDHCERDI-DECASNPCLNGGHC 502
Query: 822 QDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNL 881
Q+ +CLCPTG++G CQ +D C PC + C + C C + + G C+
Sbjct: 503 QNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCSH 562
Query: 882 -----------PLSSCQKAALS----QGIDV--SSLCHNGGLCVD-SGPSYFCHCPPGFQ 923
+ SC A S +G+ S++C G C SG + C C GF
Sbjct: 563 LKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFT 622
Query: 924 GSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTC 983
G+ C +++N CES PC+NG TC+ + Y C C+ G++G C ++ C PCHN GTC
Sbjct: 623 GTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHNGGTC 682
Query: 984 TPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWC 1043
F+C C G+ G C +C + C+ GT C+ +AF C C G G C
Sbjct: 683 RDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGT--CYDEGDAFKCMCPGGWEGTTC 740
Query: 1044 EVEIDP-CHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLC 1102
+ + C PC +GGTC S F C C +G+EGP C+ C H C++ G C
Sbjct: 741 NIARNSSCLPNPCHNGGTCVVNGES---FTCVCKEGWEGPICAQNTNDCSPHPCYNSGTC 797
Query: 1103 LPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCP 1162
+ RC C G+ GPDC C SPC + +C + G+RC CP
Sbjct: 798 VDGDN---WYRCECAPGFAGPDCRI--NINEC-QSSPCAFGATCVDEIN----GYRCVCP 847
Query: 1163 HSSPGPRCQKPGAKGCEGRSGDGACDAGCSGP-GGNWDGGDCSLGVPDPWKGCPSHSRCW 1221
G +CQ+ + C G P G WD DC+ G + S+ W
Sbjct: 848 PGHSGAKCQEVSGRPC--------ITMGSVIPDGAKWD-DDCN--TCQCLNGRIACSKVW 896
Query: 1222 LLFRDGQCHPQCDSEECLF-DGY-DCETPPACTPAYDQYCHDH 1262
C CL G+ +C + +C P D C H
Sbjct: 897 -----------CGPRPCLLHKGHSECPSGQSCIPILDDQCFVH 928
Score = 391 bits (1005), Expect = e-108
Identities = 205/668 (30%), Positives = 283/668 (42%), Gaps = 72/668 (10%)
Query: 460 NCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECAS 519
N C G+ G C + Q C P L C C G +G C+ +C
Sbjct: 217 NKTCMEGWMGPEC---NRAICRQGCSPKHGSCKLPGD--CRCQYGWQGLYCD----KCIP 267
Query: 520 APCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRS-SPCANGGQCQDQ-PGAFHCKC 577
P H C++ +QC+C + G C++D++ C + PC NGG C + P + C C
Sbjct: 268 HPGCVHGICNE---PWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSC 324
Query: 578 LPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPL--CAPNLCQ 635
G+ GP C+ CLSDPC SC + F C C G+TG C + C+PN C
Sbjct: 325 PEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNNCS 384
Query: 636 PKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSS----------CVCDVGWTG 685
C+D + C+CP G D C C + C C GW G
Sbjct: 385 HGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLPGWMG 444
Query: 686 PECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCN 745
C+ + C+ C + +C +GY C CP GY G C ++ C S PCLNGG C
Sbjct: 445 QNCDININDCLGQ-CQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQ 503
Query: 746 PSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGK 805
+ C CP +G CQ DYC PC NG C NR + C C ++G C
Sbjct: 504 NEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNCS-H 562
Query: 806 LRPSCADSPCRNRATC------QDSPQGPR----------------------CLCPTGYT 837
L+ C +PC +C D+P+G R C C G+T
Sbjct: 563 LKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKGFT 622
Query: 838 GGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDV 897
G C ++ C PC C+ S+ C+C GW G C ++ C +
Sbjct: 623 GTYCHENINDCESNPCRNGGTCIDGVNSYKCICSDGWEGAYCETNINDCSQ--------- 673
Query: 898 SSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCA 957
+ CHNGG C D ++C C G++G C + C+ C NG TC + + C C
Sbjct: 674 -NPCHNGGTCRDLVNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEGDAFKCMCP 732
Query: 958 PGYDGQNCS-KELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCH 1016
G++G C+ +C PCHN GTC F C C G+ G C + ++C PC+
Sbjct: 733 GGWEGTTCNIARNSSCLPNPCHNGGTCVVNGESFTCVCKEGWEGPICAQNTNDCSPHPCY 792
Query: 1017 PTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCP 1076
+GT C N + C+C PG G C + I+ C S PC G TC G+ C CP
Sbjct: 793 NSGT--CVDGDNWYRCECAPGFAGPDCRININECQSSPCAFGATCVDEIN---GYRCVCP 847
Query: 1077 KGFEGPTC 1084
G G C
Sbjct: 848 PGHSGAKC 855
Score = 341 bits (874), Expect = 5e-93
Identities = 207/674 (30%), Positives = 282/674 (41%), Gaps = 112/674 (16%)
Query: 661 PEDNCTCHHGHCQRSSCVCDVGWTGPECEAEL---------GGCI---SAPCAHG----- 703
P D+ H+ Q + C GW GPEC + G C C +G
Sbjct: 202 PRDDFFGHYACDQNGNKTCMEGWMGPECNRAICRQGCSPKHGSCKLPGDCRCQYGWQGLY 261
Query: 704 -GTCYPQP--------SGYNCTCPTGYTGPTCSEEMTACHS-GPCLNGGSC-NPSPGGYY 752
C P P + C C T + G C +++ C + PCLNGG+C N P Y
Sbjct: 262 CDKCIPHPGCVHGICNEPWQCLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSNTGPDKYQ 321
Query: 753 CTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCAD 812
C+CP ++GP C+ + C+S PC N G+C F C C+ G+ GP C + C+
Sbjct: 322 CSCPEGYSGPNCEIAEHACLSDPCHNRGSCKETSLGFECECSPGWTGPTCSTNI-DDCSP 380
Query: 813 SPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQ 872
+ C + TCQD G +C+CP +TG +CQ + C KPC C S++C CL
Sbjct: 381 NNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNAKSCKNLIASYYCDCLP 440
Query: 873 GWTGPLCNLP----LSSCQKAA---------------------LSQGID--VSSLCHNGG 905
GW G C++ L CQ A + ID S+ C NGG
Sbjct: 441 GWMGQNCDININDCLGQCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGG 500
Query: 906 LCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNC 965
C + + C CP GF G+LCQ ++ CE PCQNGA C + S Y C+C Y+G+NC
Sbjct: 501 HCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQNGAQCYNRASDYFCKCPEDYEGKNC 560
Query: 966 SKELDACQSQPCH---------------------------NHGTCTPKPGG-FHCACPPG 997
S D C++ PC HG C + GG F C C G
Sbjct: 561 SHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKCKSQSGGKFTCDCNKG 620
Query: 998 FVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFH 1057
F G C ++++C PC GT C N++ C C G G +CE I+ C PC +
Sbjct: 621 FTGTYCHENINDCESNPCRNGGT--CIDGVNSYKCICSDGWEGAYCETNINDCSQNPCHN 678
Query: 1058 GGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACL 1117
GGTC F C C G++G TC R C C++GG C G +C C
Sbjct: 679 GGTCRDLVND---FYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDE---GDAFKCMCP 732
Query: 1118 SGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKG 1177
G+ G C A P+PC G+C + G F C C GP C A+
Sbjct: 733 GGWEGTTCNI--ARNSSCLPNPCHNGGTCV----VNGESFTCVCKEGWEGPIC----AQN 782
Query: 1178 CEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEE 1237
S ++G G NW +C+ G P C + + Q P
Sbjct: 783 TNDCSPHPCYNSGTCVDGDNWYRCECAPGFAGP--------DCRININECQSSPCAFGAT 834
Query: 1238 CL--FDGYDCETPP 1249
C+ +GY C PP
Sbjct: 835 CVDEINGYRCVCPP 848
Score = 228 bits (581), Expect = 5e-59
Identities = 171/627 (27%), Positives = 242/627 (38%), Gaps = 134/627 (21%)
Query: 749 GGYYC------TCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRC 802
G Y C TC GP+C + C G+C PG C C G+QG C
Sbjct: 208 GHYACDQNGNKTCMEGWMGPECNRAI--CRQGCSPKHGSC-KLPG--DCRCQYGWQGLYC 262
Query: 803 EGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCA-QKPCPRNSHCLQ 861
+ C P C + Q CLC T + G C ++ C +PC C
Sbjct: 263 D-----KCIPHPGCVHGICNEPWQ---CLCETNWGGQLCDKDLNYCGTHQPCLNGGTCSN 314
Query: 862 TGPS-FHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPP 920
TGP + C C +G++GP C + +C +S CHN G C ++ + C C P
Sbjct: 315 TGPDKYQCSCPEGYSGPNCEIAEHAC----------LSDPCHNRGSCKETSLGFECECSP 364
Query: 921 GFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNH 980
G+ G C +++ C C +G TC +G+ C C P + G+ C + + C+++PC N
Sbjct: 365 GWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEAKPCVNA 424
Query: 981 GTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTG 1040
+C ++C C PG++G C+ ++++CL Q C A+C L N + C C PG+ G
Sbjct: 425 KSCKNLIASYYCDCLPGWMGQNCDININDCLGQ-CQ--NDASCRDLVNGYRCICPPGYAG 481
Query: 1041 QWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGG 1100
CE +ID C S PC +GG C+ F C CP GF G C C + C +G
Sbjct: 482 DHCERDIDECASNPCLNGGHCQNEINR---FQCLCPTGFSGNLCQLDIDYCEPNPCQNGA 538
Query: 1101 LCLPSPKPGFPPRCACLSGYGGPDC--------LTP--------------PAPKG----- 1133
C F C C Y G +C TP P+G
Sbjct: 539 QCYNRASDYF---CKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYIS 595
Query: 1134 ---CGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEG---RSG---- 1183
CGP +G C + G F C C G C + CE R+G
Sbjct: 596 SNVCGP------HGKCKSQS---GGKFTCDCNKGFTGTYCHE-NINDCESNPCRNGGTCI 645
Query: 1184 DGACDAGCSGPGGNWDGGDCSLGVPD-------------------------PWKGCPSHS 1218
DG C G W+G C + D WKG HS
Sbjct: 646 DGVNSYKCICSDG-WEGAYCETNINDCSQNPCHNGGTCRDLVNDFYCDCKNGWKGKTCHS 704
Query: 1219 R---C--WLLFRDGQCHPQCDSEECL----FDGYDCETP--PACTPAYDQYCHDHFHNGH 1267
R C G C+ + D+ +C+ ++G C +C P CH + G
Sbjct: 705 RDSQCDEATCNNGGTCYDEGDAFKCMCPGGWEGTTCNIARNSSCLP---NPCH---NGGT 758
Query: 1268 CEKGCNTAEC----GWDGGDCRPEDGD 1290
C + C GW+G C D
Sbjct: 759 CVVNGESFTCVCKEGWEGPICAQNTND 785
>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
Length = 1200
Score = 437 bits (1123), Expect = e-122
Identities = 263/802 (32%), Positives = 341/802 (42%), Gaps = 94/802 (11%)
Query: 298 YTC------LCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTS 351
YTC C + W G +C E V C+ QG G T C C GW G
Sbjct: 221 YTCDQYGNKACMDGWMGKECKEAV--CK-QGCNLLHGGCTVPGE-----CRCSYGWQGRF 272
Query: 352 CEENLDDCIAATCAPGSTCIDR--VGSFSCLCPPGRTGLLCHLE-DMCLSQ-PCHGDAQC 407
C+E C P C+ V + C C GLLC + + C S PC C
Sbjct: 273 CDE---------CVPYPGCVHGSCVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTC 323
Query: 408 STNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY 467
N C C GYSG C + C +PC +GGSC P F C CP G+
Sbjct: 324 -INAEPDQYRCTCPDGYSGRNCEKAEHACTS-----NPCANGGSCHEVPSGFECHCPSGW 377
Query: 468 TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHAD 527
+G C D +EC S PC G TC+D + F C+CP G C+++ N+C C +
Sbjct: 378 SGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQ-CQHGGT 436
Query: 528 CHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQ 587
C DL+NG+QC+C GF G CE + DEC SSPC +GG C+D FHC C GF GP C+
Sbjct: 437 CKDLVNGYQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPLCE 496
Query: 588 TEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPL--CAPNLCQPKQICKDQKD 645
+VD C PC GA C +L G ++C CP F G+ C VP C C+ C
Sbjct: 497 VDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGS--- 553
Query: 646 KANCLCPDGSPGCAPPEDNCTCH-HGHCQRS-----SCVCDVGWTGPECEAELGGCISAP 699
D PG + C HG C SC+CD G+TG C + C+ P
Sbjct: 554 -------DAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQP 606
Query: 700 CAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSH 759
C +GGTC + + C CP+G+ G C C PC + G C +YC C
Sbjct: 607 CRNGGTCIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGW 666
Query: 760 TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRA 819
G C + C + C NGGTC + TF C C G++G C SC +PC N
Sbjct: 667 KGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGG 726
Query: 820 TCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLC 879
TC S C+C G+ G +C + C PC C+ F C C G+ GP C
Sbjct: 727 TCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDC 786
Query: 880 NLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPC 939
+ + CQ SS C G CVD Y C CPPG G CQ+ + R C
Sbjct: 787 RINIDECQ----------SSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIG--FGRSC 834
Query: 940 QNGATCMAQPSGYL-----CQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCAC 994
+ T S ++ C+C G ++CSK C +PC G +P C
Sbjct: 835 WSRGTPFPHGSSWVEDCNSCRCLDG--RRDCSKVW--CGWKPCLLAG----QPEALSAQC 886
Query: 995 PPGFVGLRC-EGDVDECLDQPCHPTGTAACHSLANAFYCQCLP--GHTGQWCEVEIDPCH 1051
P +G RC E +CL PC G + CLP GH C
Sbjct: 887 P---LGQRCLEKAPGQCLRPPCEAWGECGAEEPPST---PCLPRSGHLDNNC-------- 932
Query: 1052 SQPCFHGGTCEATAGSPLGFIC 1073
++ H G+ +G IC
Sbjct: 933 ARLTLHFNRDHVPQGTTVGAIC 954
Score = 397 bits (1019), Expect = e-110
Identities = 233/756 (30%), Positives = 322/756 (42%), Gaps = 74/756 (9%)
Query: 17 CVSVVRPRGLLCGSFPEPCANGGTCLSLSLG----QGTCQCAPGFLGETCQFPDPCQNAQ 72
C RPR G + C+ +G + C+ L C P C+ +
Sbjct: 207 CNKFCRPRNDFFGHYTCDQYGNKACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSY 266
Query: 73 LCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGR 132
Q G C +P P + S + C C + G C L C+ G
Sbjct: 267 GWQ-GRFCDECVPYPGCVHGS---CVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGT 322
Query: 133 CHIQASGRPQCSCMPGWTGEQCQLRDF-CSANPCVNGGVCLATYPQIQCHCPPGFEGHAC 191
C + +C+C G++G C+ + C++NPC NGG C +CHCP G+ G C
Sbjct: 323 CINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTC 382
Query: 192 ERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRG-CSNGGTCQ 250
D++EC + PC G +C + + F+C+CP G C+L C RG C +GGTC+
Sbjct: 383 ALDIDECASN--PCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDC--RGQCQHGGTCK 438
Query: 251 LMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWD 310
+ + C+CP GF G CE+ D C S C +GG C+D D + C CP+ ++G
Sbjct: 439 DLVNG----YQCVCPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCHCPQGFSGPL 494
Query: 311 CSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDC----------- 359
C DVD CE P CRNG C N G ++C C +GG +C + C
Sbjct: 495 CEVDVDLCE---PSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGC 551
Query: 360 ------------IAATCAPGSTCIDRV-GSFSCLCPPGRTGLLCHLE-DMCLSQPCHGDA 405
+ C P C+ + G+FSC+C G TG CH D CL QPC
Sbjct: 552 GSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGG 611
Query: 406 QCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPP 465
C + C C G+ G C + ++CL P PC G C + F C C
Sbjct: 612 TCIDE--VDAFRCFCPSGWEGELCDTNPNDCL-----PDPCHSRGRCYDLVNDFYCACDD 664
Query: 466 GYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETN-ECASAPCLN 524
G+ G C + +C + C G TC D TF C CPPG +G C V N C PC+N
Sbjct: 665 GWKGKTCHSREFQCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVN 724
Query: 525 HADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGP 584
C F CIC G+ G C + ++C PC NGG C D F C+C PGF GP
Sbjct: 725 GGTCVGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGP 784
Query: 585 RCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQI----- 639
C+ +DEC S PC GA+C+D + C CP G G C+ + C +
Sbjct: 785 DCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGRSCWSRGTPFPHG 844
Query: 640 CKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHC------QRSSCVCDVGWTGPEC-EAEL 692
+D +C C DG C+ C C + S C + G C E
Sbjct: 845 SSWVEDCNSCRCLDGRRDCS----KVWCGWKPCLLAGQPEALSAQCPL---GQRCLEKAP 897
Query: 693 GGCISAPCAHGGTC-YPQPSGYNCTCPTGYTGPTCS 727
G C+ PC G C +P C +G+ C+
Sbjct: 898 GQCLRPPCEAWGECGAEEPPSTPCLPRSGHLDNNCA 933
Score = 395 bits (1014), Expect = e-109
Identities = 246/778 (31%), Positives = 340/778 (43%), Gaps = 106/778 (13%)
Query: 539 CLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPC 598
C+ G+ G C+E + C+ G C PG C+C G++G C DEC+ P
Sbjct: 231 CMDGWMGKECKEAV--CKQGCNLLHGGCT-VPG--ECRCSYGWQGRFC----DECVPYPG 281
Query: 599 PVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGC 658
V SC++ + C C + + G LC+ L N C C +
Sbjct: 282 CVHGSCVE---PWQCNCETNWGGLLCDKDL---NYCGSHHPCTN---------------- 319
Query: 659 APPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCP 718
TC + + C C G++G CE C S PCA+GG+C+ PSG+ C CP
Sbjct: 320 -----GGTCINAEPDQYRCTCPDGYSGRNCEKAEHACTSNPCANGGSCHEVPSGFECHCP 374
Query: 719 TGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFN 778
+G++GPTC+ ++ C S PC GG+C G+ C CP G CQ + C C +
Sbjct: 375 SGWSGPTCALDIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDC-RGQCQH 433
Query: 779 GGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTG 838
GGTC + + C+C GF G CE + R CA SPC + C+D G C CP G++G
Sbjct: 434 GGTCKDLVNGYQCVCPRGFGGRHCELE-RDECASSPCHSGGLCEDLADGFHCHCPQGFSG 492
Query: 839 GSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALS------ 892
C+ +DLC PC + C ++C C + G C++P C A
Sbjct: 493 PLCEVDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCG 552
Query: 893 -------QGIDVSSLCHNGGLCVDS-GPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGAT 944
G S +C G CV G ++ C C GF G+ C ++++ C +PC+NG T
Sbjct: 553 SDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGT 612
Query: 945 CMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCE 1004
C+ + + C C G++G+ C + C PCH+ G C F+CAC G+ G C
Sbjct: 613 CIDEVDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCH 672
Query: 1005 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEV-EIDPCHSQPCFHGGTCEA 1063
+C C GT C+ + F C C PG G C V + C PC +GGTC
Sbjct: 673 SREFQCDAYTCSNGGT--CYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTC-- 728
Query: 1064 TAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGP 1123
GS F C C G+EG TC+H C C++GG+C+ RC C G+ GP
Sbjct: 729 -VGSGASFSCICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWF---RCECAPGFAGP 784
Query: 1124 DCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQK----------P 1173
DC C SPC Y +C + G+RCSCP GPRCQ+
Sbjct: 785 DCRI--NIDEC-QSSPCAYGATCVDEIN----GYRCSCPPGRAGPRCQEVIGFGRSCWSR 837
Query: 1174 GAKGCEGRSGDGACDA--------GCSGPGGNWDGGDCSL-GVPDPWKG-CPSHSRCWLL 1223
G G S C++ CS W C L G P+ CP RC L
Sbjct: 838 GTPFPHGSSWVEDCNSCRCLDGRRDCSKVWCGWK--PCLLAGQPEALSAQCPLGQRC-LE 894
Query: 1224 FRDGQC-HPQCDS-EECLFDGYDCETPPA--CTPA---YDQYCHD---HFHNGHCEKG 1271
GQC P C++ EC E PP+ C P D C HF+ H +G
Sbjct: 895 KAPGQCLRPPCEAWGEC-----GAEEPPSTPCLPRSGHLDNNCARLTLHFNRDHVPQG 947
Score = 387 bits (994), Expect = e-107
Identities = 243/775 (31%), Positives = 324/775 (41%), Gaps = 106/775 (13%)
Query: 182 CPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSF----QCLCPVGQEGPRCELRAGP 237
C G+ G C+ V C +G C+ G +C C G +G C+
Sbjct: 231 CMDGWMGKECKEAV---------CKQG--CNLLHGGCTVPGECRCSYGWQGRFCD----E 275
Query: 238 CPPR-GCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQ-CQNGGTCQDGL 295
C P GC +G + C C + G C+ + + C SH C NGGTC +
Sbjct: 276 CVPYPGCVHGSCVEPWQ--------CNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAE 327
Query: 296 -DTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEE 354
D Y C CP+ ++G +C + C T P C NGG+C F C C SGW G +C
Sbjct: 328 PDQYRCTCPDGYSGRNCEKAEHAC-TSNP--CANGGSCHEVPSGFECHCPSGWSGPTCAL 384
Query: 355 NLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DMCLSQPCHGDAQCSTNPLT 413
++D+C + CA G TC+D+V F C+CP G C L+ + C Q HG + L
Sbjct: 385 DIDECASNPCAAGGTCVDQVDGFECICPEQWVGATCQLDVNDCRGQCQHGG---TCKDLV 441
Query: 414 GSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCE 473
C+C G+ G C + DEC SPC GG C + F+C CP G++G CE
Sbjct: 442 NGYQCVCPRGFGGRHCELERDEC-----ASSPCHSGGLCEDLADGFHCHCPQGFSGPLCE 496
Query: 474 ADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNEC---------------- 517
D + C PC G+ C +L ++C CP G+ C V C
Sbjct: 497 VDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPCPGGACRVIDGCGSDAG 556
Query: 518 -------ASAPCLNHADCHDLLNG-FQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQ 569
AS C H C G F CIC GF+GT C E+ID+C PC NGG C D+
Sbjct: 557 PGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRNGGTCIDE 616
Query: 570 PGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVP-- 627
AF C C G+EG C T ++CL DPC C DL F+C C G+ G+ C
Sbjct: 617 VDAFRCFCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREF 676
Query: 628 LCAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPED-----NCTCHHGHCQRS----S 676
C C C D D C CP G G CA ++ N + G C S S
Sbjct: 677 QCDAYTCSNGGTCYDSGDTFRCACPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASFS 736
Query: 677 CVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSG 736
C+C GW G C C PC +GG C + + C C G+ GP C + C S
Sbjct: 737 CICRDGWEGRTCTHNTNDCNPLPCYNGGICVDGVNWFRCECAPGFAGPDCRINIDECQSS 796
Query: 737 PCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTF-----SC 791
PC G +C GY C+CPP GP+CQ + C++ GT ++ SC
Sbjct: 797 PCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGF--GRSCWSRGTPFPHGSSWVEDCNSC 854
Query: 792 LCAMGFQGPRCEGKLRPSCADSPC----RNRATCQDSPQGPRCLCPTGYTGGSCQTLMDL 847
C G + C + C PC + A P G RCL +
Sbjct: 855 RCLDGRRD--CS---KVWCGWKPCLLAGQPEALSAQCPLGQRCL----------EKAPGQ 899
Query: 848 CAQKPCPRNSHC-LQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLC 901
C + PC C + PS CL G C + + QG V ++C
Sbjct: 900 CLRPPCEAWGECGAEEPPSTPCLPRSGHLDNNCARLTLHFNRDHVPQGTTVGAIC 954
Score = 40.4 bits (93), Expect = 0.018
Identities = 47/186 (25%), Positives = 64/186 (34%), Gaps = 42/186 (22%)
Query: 1115 ACLSGYGGPDCLTPPAPKGCG-PPSPCLYNGSCSETTGLGG---------PGFRCSCPHS 1164
AC+ G+ G +C +GC C G C + G G PG C H
Sbjct: 230 ACMDGWMGKECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPYPG----CVHG 285
Query: 1165 SPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGN---WDGGDCSLGVPDPWK-GCPSHSRC 1220
S C +P CE G CD + G + +GG C PD ++ CP
Sbjct: 286 S----CVEPWQCNCETNWGGLLCDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCP----- 336
Query: 1221 WLLFRDGQCHPQCDSEECLFDGYDCETPPACTPAYDQYCHD--HFHNGHCEKGCNTAECG 1278
DG C+ E + C + P A CH+ HC G + C
Sbjct: 337 -----DGYSGRNCEKAE-----HACTSNPC---ANGGSCHEVPSGFECHCPSGWSGPTCA 383
Query: 1279 WDGGDC 1284
D +C
Sbjct: 384 LDIDEC 389
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 419 bits (1078), Expect = e-116
Identities = 412/1413 (29%), Positives = 513/1413 (36%), Gaps = 335/1413 (23%)
Query: 37 NGGT---CLSLSLGQGTCQCAPGFL----GETCQFPDPCQNA------------------ 71
NGG C+ L++ + CQC PGF G C PC N
Sbjct: 210 NGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCE 269
Query: 72 -----QLCQNGGSCQALLPAPLGLPSSPSPLTP---SFLCTCLPGFT----GERCQAKLE 119
QL +G +C+ + GL SF C C G+ G +C ++E
Sbjct: 270 CHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCY-RIE 328
Query: 120 DPCPPSFCSKRGRCH---IQASGRPQCSCMPGWTGEQCQLR----DFCSANPCVNGGVCL 172
S + G C S P C+C G+ + Q D C+ +PC VC
Sbjct: 329 MEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQ-VCT 387
Query: 173 ATYPQIQCHCPPGF----EGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQ-- 226
+C C G+ +G CE DV+EC G C C N GSFQC C G
Sbjct: 388 NNPGGYECGCYAGYRLSADGCGCE-DVDECASSRGGCEH--HCTNLAGSFQCSCEAGYRL 444
Query: 227 ----------EGPRCELRAG-----PCPPRGCSNGGTCQLMPEKD--------------S 257
E P +L P P QL + D +
Sbjct: 445 HEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHT 504
Query: 258 TFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDE 317
+C G DC + D+C +NGGTC GLD C CPE WTG C+E
Sbjct: 505 LTEKFVCLDDSFGHDCSLTCDDC-----RNGGTCLLGLDG--CDCPEGWTGLICNETCPP 557
Query: 318 CETQGPP-----HCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCI-------AATCA 365
+T G C+NGGTC + G+ C C G GT+CE+ CA
Sbjct: 558 -DTFGKNCSFSCSCQNGGTCDSVTGA--CRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCA 614
Query: 366 PGSTCIDRVGSFSCLCPPGRTGLLCHLE--DMCLSQPCHGDAQCSTNPLTGST-----LC 418
C G+ CLC PG G CHL C + QC P T S C
Sbjct: 615 NRGRCHRLYGA--CLCDPGLYGRFCHLTCPPWAFGPGCSEECQC-VQPHTQSCDKRDGSC 671
Query: 419 LCQPGYSGPTCHQDLDECLMAQQGPS-----PCEHGGSCLNTPGSFNCLCPPGYTGSRCE 473
C+ G+ G C EC + GP C G +C + G CP G+ G C
Sbjct: 672 SCKAGFRGERCQA---ECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCG 728
Query: 474 AD------------HNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNE----- 516
+ C PCH T C CPPG G+ CE + E
Sbjct: 729 QECPVGTFGVNCSSSCSCGGAPCHG--------VTGQCRCPPGRTGEDCEADCPEGRWGL 780
Query: 517 -CAS-APCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSP-------CANGGQCQ 567
C P HA D G C+CLPGF G+RC++ P CAN G C
Sbjct: 781 GCQEICPACQHAARCDPETG-ACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSCANDGHCH 839
Query: 568 DQPGAFHCKCLPGFEGPRCQTEVD------ECLSDPCPVGA---SCLDLPGAFFCLCPSG 618
P HC C PG+ G CQ D +C S PC A SC + G CLC +G
Sbjct: 840 --PATGHCSCAPGWTGFSCQRACDTGHWGPDC-SHPCNCSAGHGSCDAISG--LCLCEAG 894
Query: 619 FTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDG--SPGCAPPEDNCTCHHGH-CQRS 675
+ G CE CP G PGC E C C HG C
Sbjct: 895 YVGPRCEQQ-----------------------CPQGHFGPGC---EQRCQCQHGAACDHV 928
Query: 676 S--CVCDVGWTGPECEAELGG------CISA-PCAHGGTCYPQPSGYNCTCPTGYTGPTC 726
S C C GW G CE C SA C G C +C CP G GP C
Sbjct: 929 SGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGAAC--DAVNGSCLCPAGRRGPRC 986
Query: 727 SEEMTACHSG-------PCLNGGSCNPSPGGYYCTCPPSHTGPQCQTST------DYCV- 772
+E A G C NG SC+P G C C P GP C + D C
Sbjct: 987 AETCPAHTYGHNCSQACACFNGASCDPVHG--QCHCAPGWMGPSCLQACPAGLYGDNCRH 1044
Query: 773 SAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDS----PQGP 828
S C NGGTC P + C C G+ G CE + P + CR+ C + P
Sbjct: 1045 SCLCQNGGTC--DPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTG 1102
Query: 829 RCLCPTGYTGGSCQT------LMDLCAQK-PCPRNSHCLQTGPSFHCLCLQGWTGPLCNL 881
RCLCP G+TG CQ+ + CAQ+ CP + C + C C G+TG
Sbjct: 1103 RCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGA--CRCPPGFTG----- 1155
Query: 882 PLSSCQKAAL--SQGIDVSSLCHNGGLCVDSGPSY-FCHCPPGFQGSLCQDHVNPCESRP 938
S C++A S G D + +C G P+ C C G+ G CQ P P
Sbjct: 1156 --SGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGP 1213
Query: 939 -------CQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQP-------CHNHGTCT 984
C NG +C A C+C G+ G +C+ + P C C
Sbjct: 1214 GCEQLCGCLNGGSCDAATGA--CRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACD 1271
Query: 985 PKPGGFHCACPPGFVGLRCEGDVDEC-----LDQPCHPTGTAACHSLANAFYCQCLPGHT 1039
P G C CPPG G+RCE + + C CH+ + C C G T
Sbjct: 1272 PVTGT--CLCPPGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNGS--CSCGLGWT 1327
Query: 1040 GQWCEVEIDP------CHSQ-PCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCG 1092
G+ CE+ P CH + C + TCE G+ C C GF G C H P G
Sbjct: 1328 GRHCELACPPGRYGAACHLECSCHNNSTCEPATGT-----CRCGPGFYGQACEHPCPP-G 1381
Query: 1093 FHH--------CHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAP----KGCGPPSPC 1140
FH C HG C P RC C +G+ G C P +GC C
Sbjct: 1382 FHGAGCQGLCWCQHGAPCDP-----ISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDC 1436
Query: 1141 LYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWDG 1200
C TGL C CP G C +G G S CD G G
Sbjct: 1437 DGGAPCDPVTGL------CLCPPGRSGATCNLDCRRGQFGPSCTLHCDCG--------GG 1482
Query: 1201 GDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQC 1233
DC DP G +C + DG P C
Sbjct: 1483 ADC-----DPVSG-----QCHCV--DGYMGPTC 1503
Score = 386 bits (992), Expect = e-106
Identities = 412/1435 (28%), Positives = 513/1435 (35%), Gaps = 300/1435 (20%)
Query: 35 CANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSS 93
C +GG C+ S C C PGF G CQ+ D C+ NGG + P
Sbjct: 133 CFHGGRCVPGSAQP--CHCPPGFQGPRCQYDVDECRT----HNGGCQHRCVNTP------ 180
Query: 94 PSPLTPSFLCTCLPGF---TGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWT 150
S+LC C PGF T R + C + C R +C C PG+
Sbjct: 181 -----GSYLCECKPGFRLHTDSRTCLAINS-CALGNGGCQHHCVQLTITRHRCQCRPGFQ 234
Query: 151 ----GEQCQLRDFCSANPCVN-GGVCLATYPQIQ----CHCPPGFE----GHACERDVNE 197
G C R +PC N G C+ ++ C C G++ G ACE DV+E
Sbjct: 235 LQEDGRHCVRR-----SPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACE-DVDE 288
Query: 198 CFQDPGPCPKGTSCHNTLGSFQCLCPVGQE----GPRCELRAGPCPPRGCSNGGTCQLMP 253
C C G C NT GSF+C+C G E G +C +N G C
Sbjct: 289 CAAGLAQCAHG--CLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGC 346
Query: 254 EKDSTFHLCLCPPGF-IGPDCE--VNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWT--- 307
S LC CP G+ + D ++ D+C C C + Y C C +
Sbjct: 347 SHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCCQQ-VCTNNPGGYECGCYAGYRLSA 405
Query: 308 -GWDCSEDVDECETQGPPHCRNGGT---CQNSAGSFHCVCVSGWGGTSCEENLDDCIAAT 363
G C EDVDEC + GG C N AGSF C C +G+ E+ C
Sbjct: 406 DGCGC-EDVDECASS------RGGCEHHCTNLAGSFQCSCEAGY---RLHEDRRGCSPLE 455
Query: 364 CAPGSTCIDRVGSFSCLCP-PGRTGLLCHLEDMCLSQPCHGDAQCST----NPLTGSTLC 418
+D G + P P L L + D + + + LT +C
Sbjct: 456 ----EPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVC 511
Query: 419 LCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEAD--- 475
L G C D+C +GG+CL G C CP G+TG C
Sbjct: 512 LDDS--FGHDCSLTCDDC----------RNGGTCLL--GLDGCDCPEGWTGLICNETCPP 557
Query: 476 ----HNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCE------VETNECAS-APCLN 524
N S C G TC + T C CPPG+ G CE C C N
Sbjct: 558 DTFGKNCSFSCSCQNGGTCDSV--TGACRCPPGVSGTNCEDGCPKGYYGKHCRKKCNCAN 615
Query: 525 HADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSP-CANGGQCQDQPGAFHC-------K 576
CH L C+C PG G C P C+ QC QP C
Sbjct: 616 RGRCHRLYGA--CLCDPGLYGRFCHLTCPPWAFGPGCSEECQCV-QPHTQSCDKRDGSCS 672
Query: 577 CLPGFEGPRCQTEVDECLSDP-------CPVGASCLDLPGAFFCLCPSGFTGQLCEVPLC 629
C GF G RCQ E + P CPVG +C + G CP+GF G+ C
Sbjct: 673 CKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQE-- 730
Query: 630 APNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQ--RSSCVCDVGWTGPE 687
CP G+ G +C+C C C C G TG +
Sbjct: 731 ---------------------CPVGTFG-VNCSSSCSCGGAPCHGVTGQCRCPPGRTGED 768
Query: 688 CEAELG------GC--ISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGP-- 737
CEA+ GC I C H C P+ C C G+ G C + A GP
Sbjct: 769 CEADCPEGRWGLGCQEICPACQHAARCDPETGA--CLCLPGFVGSRCQDVCPAGWYGPSC 826
Query: 738 -----CLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAP-CFNGGTCVNRPGTFS- 790
C N G C+P+ G +C+C P TG CQ + D P C + C G+
Sbjct: 827 QTRCSCANDGHCHPATG--HCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDA 884
Query: 791 ----CLCAMGFQGPRCE-----GKLRPSCAD-SPCRNRATCQDSPQGPRCLCPTGYTGGS 840
CLC G+ GPRCE G P C C++ A C D G C CP G+ G
Sbjct: 885 ISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAAC-DHVSG-ACTCPAGWRGTF 942
Query: 841 CQTL-------MDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQ 893
C+ +D + C + C S CLC G GP C +C
Sbjct: 943 CEHACPAGFFGLDCRSACNCTAGAACDAVNGS--CLCPAGRRGPRC---AETCPAHTYGH 997
Query: 894 GIDVSSLCHNGGLCVDSGPSY-FCHCPPGFQGSLCQDHV-------NPCESRPCQNGATC 945
+ C NG C P + CHC PG+ G C N S CQNG TC
Sbjct: 998 NCSQACACFNGASC---DPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTC 1054
Query: 946 MAQPSGYLCQCAPGYDGQNCSKEL------DACQ-SQPCHNHGTCTPKPGGFHCACPPGF 998
P C C G+ G C KE C+ S C N G C P G C CP G+
Sbjct: 1055 --DPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTG--RCLCPAGW 1110
Query: 999 VGLRCE-----GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDP-CHS 1052
G +C+ G E Q C AACH + A C+C PG TG CE P
Sbjct: 1111 TGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGA--CRCPPGFTGSGCEQACPPGSFG 1168
Query: 1053 QPCFHGGTC--EATAGSPLGFICHCPKGFEGPTCSHRAPS----------CGFHHCHHGG 1100
+ C C E A P C C G+ GP+C R P CG C +GG
Sbjct: 1169 EDCAQMCQCPGENPACHPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCG---CLNGG 1225
Query: 1101 LCLPSPKPGFPPRCACLSGYGGPDC-LTPPAPK---GCGPPSPCLYNGSCSETTGL---- 1152
C C C +G+ G DC LT P + C C +C TG
Sbjct: 1226 SC-----DAATGACRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGTCLCP 1280
Query: 1153 -GGPGFRC--SCPHSSPGPRCQKPGAKGCEGRSGDGACDA--GCSGPGGNWDGGDCSLGV 1207
G G RC CP + G C+ C R+G G C A G G W G C L
Sbjct: 1281 PGRAGVRCERGCPQNRFGVGCEHT----CSCRNG-GLCHASNGSCSCGLGWTGRHCELAC 1335
Query: 1208 PDPWKGCPSHSRCWLLFRDGQCHPQCDSEEC--LFDGYDCETPPACTPAYDQ-------- 1257
P G H C + C P + C F G CE P C P +
Sbjct: 1336 PPGRYGAACHLEC-SCHNNSTCEPATGTCRCGPGFYGQACEHP--CPPGFHGAGCQGLCW 1392
Query: 1258 --------------YCHDHFHNGHCEKGCNTA--------ECGWDGG-DCRPEDG 1289
C FH CE+GC C DGG C P G
Sbjct: 1393 CQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQRCDCDGGAPCDPVTG 1447
Score = 350 bits (899), Expect = 6e-96
Identities = 330/1133 (29%), Positives = 411/1133 (36%), Gaps = 269/1133 (23%)
Query: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGF-------------LGETCQFPDPCQNAQLC 74
C + C NGGTCL LG C C G+ G+ C F C C
Sbjct: 520 CSLTCDDCRNGGTCL---LGLDGCDCPEGWTGLICNETCPPDTFGKNCSF--SCS----C 570
Query: 75 QNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSF-------- 126
QNGG+C ++ A C C PG +G C ED CP +
Sbjct: 571 QNGGTCDSVTGA----------------CRCPPGVSGTNC----EDGCPKGYYGKHCRKK 610
Query: 127 --CSKRGRCHIQASGRPQCSCMPGWTGEQCQLR--DFCSANPCVNGGVCLATYPQI---- 178
C+ RGRCH C C PG G C L + C C+ + Q
Sbjct: 611 CNCANRGRCHRLYGA---CLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKR 667
Query: 179 --QCHCPPGFEGHACERDVNECFQDPG-----PCPKGTSCHNTLGSFQCLCPVGQEGPRC 231
C C GF G C+ + + PG CP G +C + G CP G +G C
Sbjct: 668 DGSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDC 727
Query: 232 ELRAGPCPPR----GCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVN-PD-----NC- 280
CP CS+ +C P T C CPPG G DCE + P+ C
Sbjct: 728 ---GQECPVGTFGVNCSSSCSCGGAPCHGVTGQ-CRCPPGRTGEDCEADCPEGRWGLGCQ 783
Query: 281 -VSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPP-----HCRNGGTCQN 334
+ CQ+ C +T CLC + G C +DV GP C N G C
Sbjct: 784 EICPACQHAARCDP--ETGACLCLPGFVGSRC-QDVCPAGWYGPSCQTRCSCANDGHCHP 840
Query: 335 SAGSFHCVCVSGWGGTSCEENLD------DCI-AATCAPGSTCIDRVGSFSCLCPPGRTG 387
+ G HC C GW G SC+ D DC C+ G D + CLC G G
Sbjct: 841 ATG--HCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGL-CLCEAGYVG 897
Query: 388 LLCHLEDMC----LSQPCHGDAQCSTNPLTG--STLCLCQPGYSGPTCHQDLDECLMAQQ 441
C E C C QC S C C G+ G C
Sbjct: 898 PRC--EQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGLD 955
Query: 442 GPSPCE--HGGSCLNTPGSFNCLCPPGYTGSRCEA-------DHNECLSQPCHPGSTCLD 492
S C G +C GS CLCP G G RC HN + C G++C
Sbjct: 956 CRSACNCTAGAACDAVNGS--CLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDP 1013
Query: 493 LLATFHC-----------LCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLP 541
+ HC CP GL G C S C N C D ++G C C
Sbjct: 1014 VHGQCHCAPGWMGPSCLQACPAGLYGDNCR------HSCLCQNGGTC-DPVSG-HCACPE 1065
Query: 542 GFSGTRCEEDI------DECR-SSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEV---- 590
G++G CE++ CR S C NGG C G C C G+ G +CQ+
Sbjct: 1066 GWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTG--RCLCPAGWTGDKCQSPCLRGW 1123
Query: 591 --DECLSD-PCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKA 647
+ C CP GA+C + GA C CP GFTG CE C P +D
Sbjct: 1124 FGEACAQRCSCPPGAACHHVTGA--CRCPPGFTGSGCE------QACPPGSFGEDCAQM- 1174
Query: 648 NCLCPDGSPGCAPPEDNCTC---HHG-HCQRSSCVCDVGWTGPECEAELGGCISAPCAHG 703
C CP +P C P C+C +HG CQ+ C G GP CE G C +G
Sbjct: 1175 -CQCPGENPACHPATGTCSCAAGYHGPSCQQR---CPPGRYGPGCEQLCG------CLNG 1224
Query: 704 GTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGP-------CLNGGSCNPSPGGYYCTCP 756
G+C C CPTG+ G C+ GP C G +C+P G C CP
Sbjct: 1225 GSCDAATGA--CRCPTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTG--TCLCP 1280
Query: 757 PSHTGPQCQTSTDY------CV-SAPCFNGGTCVNRPGTFSCLCAMGFQGPRCE-----G 804
P G +C+ C + C NGG C G SC C +G+ G CE G
Sbjct: 1281 PGRAGVRCERGCPQNRFGVGCEHTCSCRNGGLCHASNG--SCSCGLGWTGRHCELACPPG 1338
Query: 805 KLRPSC-ADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTG 863
+ +C + C N +TC+ P C C G+ G +C + PCP
Sbjct: 1339 RYGAACHLECSCHNNSTCE--PATGTCRCGPGFYGQAC--------EHPCP--------- 1379
Query: 864 PSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ 923
P FH QG LC C +G C S C CP GF
Sbjct: 1380 PGFHGAGCQG----LC--------------------WCQHGAPC--DPISGRCLCPAGFH 1413
Query: 924 GSLCQDHVNP------CESR-PCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQP 976
G C+ P C R C GA C P LC C PG G C+ + Q P
Sbjct: 1414 GHFCERGCEPGSFGEGCHQRCDCDGGAPC--DPVTGLCLCPPGRSGATCNLDCRRGQFGP 1471
Query: 977 -------CHNHGTCTPKPGGFHCACPPGFVGLRC-EGDVDECLDQPCHPTGTA 1021
C C P G C C G++G C EG + P G+A
Sbjct: 1472 SCTLHCDCGGGADCDPVSG--QCHCVDGYMGPTCREGGPLRLPENPSLAQGSA 1522
Score = 342 bits (877), Expect = 2e-93
Identities = 334/1158 (28%), Positives = 408/1158 (35%), Gaps = 270/1158 (23%)
Query: 145 CMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGP 204
C+ G C L + + C NGG CL C CP G+ G C
Sbjct: 511 CLDDSFGHDCSL----TCDDCRNGGTCLLGLDG--CDCPEGWTGLICNET---------- 554
Query: 205 CPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLC 264
CP T N SF C C NGGTC DS C C
Sbjct: 555 CPPDTFGKNC--SFSC---------------------SCQNGGTC------DSVTGACRC 585
Query: 265 PPGFIGPDCE------------VNPDNCVS----HQCQNGGTCQDGLDTYTC--LCPETW 306
PPG G +CE NC + H+ C GL C CP
Sbjct: 586 PPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWA 645
Query: 307 TGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLD------DC- 359
G CSE EC+ PH + +C GS C C +G+ G C+ + C
Sbjct: 646 FGPGCSE---ECQCV-QPHTQ---SCDKRDGS--CSCKAGFRGERCQAECELGYFGPGCW 696
Query: 360 IAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDM--CLSQPCHGDAQCSTNPLTGST- 416
A TC G C G CP G G C E C C P G T
Sbjct: 697 QACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAPCHGVTG 756
Query: 417 LCLCQPGYSGPTCHQDLDE---CLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCE 473
C C PG +G C D E L Q+ C+H C P + CLC PG+ GSRC+
Sbjct: 757 QCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARC--DPETGACLCLPGFVGSRCQ 814
Query: 474 ADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLN 533
+CP G G C+ + C N CH
Sbjct: 815 D-------------------------VCPAGWYGPSCQTRCS------CANDGHCHPATG 843
Query: 534 GFQCICLPGFSGTRCEEDID------ECRSSPC---ANGGQCQDQPGAFHCKCLPGFEGP 584
C C PG++G C+ D +C S PC A G C G C C G+ GP
Sbjct: 844 --HCSCAPGWTGFSCQRACDTGHWGPDC-SHPCNCSAGHGSCDAISGL--CLCEAGYVGP 898
Query: 585 RCQTEVDECLSDP-------CPVGASCLDLPGAFFCLCPSGFTGQLCE-------VPLCA 630
RC+ + + P C GA+C + GA C CP+G+ G CE L
Sbjct: 899 RCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGA--CTCPAGWRGTFCEHACPAGFFGLDC 956
Query: 631 PNLCQPKQICKDQKDKANCLCPDG--SPGCAPP----------EDNCTCHHG-HCQ--RS 675
+ C +CLCP G P CA C C +G C
Sbjct: 957 RSACNCTAGAACDAVNGSCLCPAGRRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHG 1016
Query: 676 SCVCDVGWTGPEC-EAELGGCISAPCAH------GGTCYPQPSGYNCTCPTGYTGPTCSE 728
C C GW GP C +A G C H GGTC P +C CP G+ G C +
Sbjct: 1017 QCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTC--DPVSGHCACPEGWAGLACEK 1074
Query: 729 E------MTAC-HSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFN--- 778
E C HSG CLNGG C+P G C CP TG +CQ +PC
Sbjct: 1075 ECLPRDVRAGCRHSGGCLNGGLCDPHTG--RCLCPAGWTGDKCQ--------SPCLRGWF 1124
Query: 779 GGTCVNR----PG------TFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDS---- 824
G C R PG T +C C GF G CE P C C
Sbjct: 1125 GEACAQRCSCPPGAACHHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPAC 1184
Query: 825 -PQGPRCLCPTGYTGGSCQTLMDLCAQKP-CPRNSHCLQTG----PSFHCLCLQGWTGPL 878
P C C GY G SCQ P C + CL G + C C G+ G
Sbjct: 1185 HPATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTD 1244
Query: 879 CNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNP----- 933
CNL +C + C G C + C CPPG G C+
Sbjct: 1245 CNL---TCPQGRFGPNCTHVCGCGQGAAC--DPVTGTCLCPPGRAGVRCERGCPQNRFGV 1299
Query: 934 -CE-SRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELD------ACQSQ-PCHNHGTCT 984
CE + C+NG C A S C C G+ G++C AC + CHN+ TC
Sbjct: 1300 GCEHTCSCRNGGLCHA--SNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNSTCE 1357
Query: 985 PKPGGFHCA-----------CPPGFVGLRCEGDVDECLDQPCHP-TGTAACHSLANAFYC 1032
P G C CPPGF G C+G PC P +G C + + +C
Sbjct: 1358 PATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFC 1417
Query: 1033 Q--CLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCS----- 1085
+ C PG G+ C D C G C+ G +C CP G G TC+
Sbjct: 1418 ERGCEPGSFGEGCHQRCD------CDGGAPCDPVTG-----LCLCPPGRSGATCNLDCRR 1466
Query: 1086 -HRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNG 1144
PSC HC GG P G +C C+ GY GP C + P +P L G
Sbjct: 1467 GQFGPSCTL-HCDCGGGADCDPVSG---QCHCVDGYMGPTCREGGPLR--LPENPSLAQG 1520
Query: 1145 SCSETTGLGGPGFRCSCP 1162
S P R P
Sbjct: 1521 SAGTLPASSRPTSRSGGP 1538
Score = 281 bits (719), Expect = 5e-75
Identities = 265/843 (31%), Positives = 333/843 (39%), Gaps = 213/843 (25%)
Query: 25 GLLCGSFPEPCANGGT-CLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQAL 83
G+ C S C+ GG C ++ G C+C PG GE C+ C + G CQ +
Sbjct: 737 GVNCSS---SCSCGGAPCHGVT---GQCRCPPGRTGEDCEAD--CPEGRW---GLGCQEI 785
Query: 84 LPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSF----------CSKRGRC 133
PA + P T + C CLPGF G RCQ D CP + C+ G C
Sbjct: 786 CPA-CQHAARCDPETGA--CLCLPGFVGSRCQ----DVCPAGWYGPSCQTRCSCANDGHC 838
Query: 134 HIQASGRPQCSCMPGWTGEQCQLR-------DFCSANPC----------VNGGVCL--AT 174
H A+G CSC PGWTG CQ CS +PC G+CL A
Sbjct: 839 H-PATGH--CSCAPGWTGFSCQRACDTGHWGPDCS-HPCNCSAGHGSCDAISGLCLCEAG 894
Query: 175 Y--PQIQCHCP-----PGFE-------GHACERDVNECFQDPG--------PCPKG---- 208
Y P+ + CP PG E G AC+ C G CP G
Sbjct: 895 YVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAGWRGTFCEHACPAGFFGL 954
Query: 209 ---TSCHNTLGSF------QCLCPVGQEGPRCELRAGPCPP----RGCSNGGTCQLMPEK 255
++C+ T G+ CLCP G+ GPRC A CP CS C
Sbjct: 955 DCRSACNCTAGAACDAVNGSCLCPAGRRGPRC---AETCPAHTYGHNCSQACACFNGASC 1011
Query: 256 DSTFHLCLCPPGFIGPDC------EVNPDNC-VSHQCQNGGTCQDGLDTYTCLCPETWTG 308
D C C PG++GP C + DNC S CQNGGTC D + + C CPE W G
Sbjct: 1012 DPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTC-DPVSGH-CACPEGWAG 1069
Query: 309 WDCSEDVDECETQ-GPPH---CRNGGTCQNSAGSFHCVCVSGWGGTSCEENL------DD 358
C ++ + + G H C NGG C G C+C +GW G C+ +
Sbjct: 1070 LACEKECLPRDVRAGCRHSGGCLNGGLCDPHTG--RCLCPAGWTGDKCQSPCLRGWFGEA 1127
Query: 359 CI-AATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMC----LSQPCHGDAQC-----S 408
C +C PG+ C G +C CPPG TG C E C + C QC +
Sbjct: 1128 CAQRCSCPPGAACHHVTG--ACRCPPGFTGSGC--EQACPPGSFGEDCAQMCQCPGENPA 1183
Query: 409 TNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPS-----PCEHGGSCLNTPGSFNCLC 463
+P TG+ C C GY GP+C Q C + GP C +GGSC G+ C C
Sbjct: 1184 CHPATGT--CSCAAGYHGPSCQQ---RCPPGRYGPGCEQLCGCLNGGSCDAATGA--CRC 1236
Query: 464 PPGYTGSRCEADHNECLSQP-------CHPGSTCLDLLATFHCLCPPGLEGQLCEVETNE 516
P G+ G+ C + P C G+ C + T CLCPPG G CE +
Sbjct: 1237 PTGFLGTDCNLTCPQGRFGPNCTHVCGCGQGAACDPVTGT--CLCPPGRAGVRCERGCPQ 1294
Query: 517 ------CA-SAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECR-------SSPCAN 562
C + C N CH NG C C G++G CE R C N
Sbjct: 1295 NRFGVGCEHTCSCRNGGLCH-ASNG-SCSCGLGWTGRHCELACPPGRYGAACHLECSCHN 1352
Query: 563 GGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPV---GASCLDL----------PG 609
C+ G C+C PGF G C+ PCP GA C L P
Sbjct: 1353 NSTCEPATGT--CRCGPGFYGQACE--------HPCPPGFHGAGCQGLCWCQHGAPCDPI 1402
Query: 610 AFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHH 669
+ CLCP+GF G CE C+P + + +C DG C P C C
Sbjct: 1403 SGRCLCPAGFHGHFCE------RGCEPGSFGEGCHQRCDC---DGGAPCDPVTGLCLCPP 1453
Query: 670 GHCQRSSCVCDV----GWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPT 725
G RS C++ G GP C + C G C P C C GY GPT
Sbjct: 1454 G---RSGATCNLDCRRGQFGPSC------TLHCDCGGGADC--DPVSGQCHCVDGYMGPT 1502
Query: 726 CSE 728
C E
Sbjct: 1503 CRE 1505
Score = 236 bits (601), Expect = 2e-61
Identities = 268/1011 (26%), Positives = 369/1011 (36%), Gaps = 247/1011 (24%)
Query: 432 DLDECLMAQQGPSPCEHGGSCLNTPGSFN-CLCPPGYTGSRCEADHNECLSQPCHPGSTC 490
D + CL A+ S C HGG C+ PGS C CPPG+ G RC+ D +EC + C
Sbjct: 119 DEEGCLSAECSASLCFHGGRCV--PGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRC 176
Query: 491 LDLLATFHCLCPPGL----EGQLCEVETNECA--SAPCLNHADCHDL-LNGFQCICLPGF 543
++ ++ C C PG + + C + N CA + C +H C L + +C C PGF
Sbjct: 177 VNTPGSYLCECKPGFRLHTDSRTC-LAINSCALGNGGCQHH--CVQLTITRHRCQCRPGF 233
Query: 544 SGTRCEEDIDEC-RSSPCANGG-----QCQDQPGAFHCKCLPGF----EGPRCQTEVDEC 593
+ +ED C R SPCAN +CQ G C+C G+ +G C+ +VDEC
Sbjct: 234 ---QLQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACE-DVDEC 289
Query: 594 LSDPCPVGASCLDLPGAFFCLCPSGF----TGQLC-EVPLCAPNLCQPKQICKDQKDKAN 648
+ CL+ G+F C+C +G+ G+ C + + N C+
Sbjct: 290 AAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNSCE------------- 336
Query: 649 CLCPDGSPGCAPPEDNCTCHHGHCQRSS----CVCDVGW---TGPECEAELGGCISAPCA 701
+N C HG C +S C C G+ T ++ C +PC
Sbjct: 337 -------------ANNGGCSHG-CSHTSAGPLCTCPRGYELDTDQRTCIDVDDCADSPCC 382
Query: 702 HGGTCYPQPSGYNCTCPTGY----TGPTCSEEMTACHS--GPCLNGGSCNPSPGGYYCTC 755
C P GY C C GY G C E++ C S G C + C G + C+C
Sbjct: 383 Q-QVCTNNPGGYECGCYAGYRLSADGCGC-EDVDECASSRGGCEH--HCTNLAGSFQCSC 438
Query: 756 PPSHTGPQ----CQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRC--------- 802
+ + C + V +G RP + + + P+
Sbjct: 439 EAGYRLHEDRRGCSPLEEPMVD---LDGELPFVRP--LPHIAVLQDELPQLFQDDDVGAD 493
Query: 803 --EGKLRPSCADSPCRNRATCQDSPQGPRC--LCPTGYTGGSCQTLMDLCAQKPCPRNSH 858
E +LR + + C D G C C GG+C +D
Sbjct: 494 EEEAELR---GEHTLTEKFVCLDDSFGHDCSLTCDDCRNGGTCLLGLD------------ 538
Query: 859 CLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHC 918
C C +GWTG +CN +C + S C NGG C + C C
Sbjct: 539 --------GCDCPEGWTGLICN---ETCPPDTFGKNCSFSCSCQNGGTC--DSVTGACRC 585
Query: 919 PPGFQGSLCQD------HVNPCESR-PCQNGATCMAQPSGYLCQ-----------CAPGY 960
PPG G+ C+D + C + C N C LC C P
Sbjct: 586 PPGVSGTNCEDGCPKGYYGKHCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWA 645
Query: 961 DGQNCSKELDACQ--SQPCHNH-GTCTPKPG------------GFH-------CACPPGF 998
G CS+E Q +Q C G+C+ K G G+ C CP
Sbjct: 646 FGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECELGYFGPGCWQACTCP--- 702
Query: 999 VGLRCEGDVDEC------------LDQPCHPTGT-------------AACHSLANAFYCQ 1033
VG+ C+ EC Q C P GT A CH + C+
Sbjct: 703 VGVACDSVSGECGKRCPAGFQGEDCGQEC-PVGTFGVNCSSSCSCGGAPCHGVTG--QCR 759
Query: 1034 CLPGHTGQWCEVEIDP------CHS--QPCFHGGTCEATAGSPL---GFI---CH--CPK 1077
C PG TG+ CE + C C H C+ G+ L GF+ C CP
Sbjct: 760 CPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARCDPETGACLCLPGFVGSRCQDVCPA 819
Query: 1078 GFEGPTCSHRAPSCGFHHCHHG-GLCLPSPK-PGFPPRCACLSGYGGPDCLTPPAPKGCG 1135
G+ GP+C R HCH G C +P GF + AC +G+ GPDC + P G
Sbjct: 820 GWYGPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDC-SHPCNCSAG 878
Query: 1136 PPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGP----RCQKPGAKGCEGRSGDGACDAGC 1191
S +G C G GP CP GP RCQ C+ SG C AG
Sbjct: 879 HGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGPGCEQRCQCQHGAACDHVSGACTCPAG- 937
Query: 1192 SGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCETPPAC 1251
W G C P + G S C + CD+ C P
Sbjct: 938 ------WRGTFCEHACPAGFFGLDCRSAC-----NCTAGAACDAV-----NGSCLCPAGR 981
Query: 1252 T-PAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRPEDGD----PEW-GPS 1296
P + C H + +C + C ++G C P G P W GPS
Sbjct: 982 RGPRCAETCPAHTYGHNCSQAC----ACFNGASCDPVHGQCHCAPGWMGPS 1028
Score = 176 bits (446), Expect = 2e-43
Identities = 202/730 (27%), Positives = 259/730 (35%), Gaps = 174/730 (23%)
Query: 679 CDVGWTGPECEAELGGCISAPCA-----HGGTCYPQPSGYNCTCPTGYTGPTCSEEMTAC 733
C GW E GC+SA C+ HGG C P S C CP G+ GP C ++ C
Sbjct: 110 CCRGWMQQPDEE---GCLSAECSASLCFHGGRCVPG-SAQPCHCPPGFQGPRCQYDVDEC 165
Query: 734 --HSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCV---SAPCFNGGT---CVNR 785
H+G C + C +PG Y C C P G + T + C+ S NGG CV
Sbjct: 166 RTHNGGCQH--RCVNTPGSYLCECKP---GFRLHTDSRTCLAINSCALGNGGCQHHCVQL 220
Query: 786 PGT-FSCLCAMGFQGPRCEGKLRPSCADSPCRNR-----ATCQDSPQGPRCLCPTGY--- 836
T C C GFQ + R SPC NR CQ RC C GY
Sbjct: 221 TITRHRCQCRPGFQ---LQEDGRHCVRRSPCANRNGSCMHRCQVVRGLARCECHVGYQLA 277
Query: 837 -TGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGI 895
G +C+ +D CA CL T SF C+C G+ L Q + I
Sbjct: 278 ADGKACED-VDECAAGLAQCAHGCLNTQGSFKCVCHAGY-----ELGADGRQCYRIEMEI 331
Query: 896 DVSSLCHNGGL---CVDSGPSYFCHCPPGFQ----GSLCQDHVNPCESRPCQNGATCMAQ 948
S +NGG C + C CP G++ C D V+ C PC C
Sbjct: 332 VNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDTDQRTCID-VDDCADSPCCQ-QVCTNN 389
Query: 949 PSGYLCQCAPGY----DGQNCSKELDACQSQ--PCHNHGTCTPKPGGFHCACPPGFVGLR 1002
P GY C C GY DG C +++D C S C +H CT G F C+C G+ R
Sbjct: 390 PGGYECGCYAGYRLSADGCGC-EDVDECASSRGGCEHH--CTNLAGSFQCSCEAGY---R 443
Query: 1003 CEGDVDEC--LDQP----------CHPTGTAAC--------------------------H 1024
D C L++P P A H
Sbjct: 444 LHEDRRGCSPLEEPMVDLDGELPFVRPLPHIAVLQDELPQLFQDDDVGADEEEAELRGEH 503
Query: 1025 SLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1084
+L F CL G C + D C +GGTC C CP+G+ G C
Sbjct: 504 TLTEKFV--CLDDSFGHDCSLTCDDCR-----NGGTCLLGLDG-----CDCPEGWTGLIC 551
Query: 1085 SHRAP------SCGFH-HCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKG---- 1133
+ P +C F C +GG C C C G G +C PKG
Sbjct: 552 NETCPPDTFGKNCSFSCSCQNGGTC-----DSVTGACRCPPGVSGTNC-EDGCPKGYYGK 605
Query: 1134 -CGPPSPCLYNGSCSETTG--LGGPGF-----RCSCPHSSPGP------RCQKPGAKGCE 1179
C C G C G L PG +CP + GP +C +P + C+
Sbjct: 606 HCRKKCNCANRGRCHRLYGACLCDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCD 665
Query: 1180 GRSGDGACDAGCSGPGGNWDGGDCSLGV--PDPWKGCPSHSRCWLLFRDGQCHPQCDSEE 1237
R G +C AG G +C LG P W+ C G+C +C +
Sbjct: 666 KRDGSCSCKAGFRGERCQ---AECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAG- 721
Query: 1238 CLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGCN---------TAEC----GWDGGDC 1284
F G DC Q C +C C+ T +C G G DC
Sbjct: 722 --FQGEDC----------GQECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDC 769
Query: 1285 RPEDGDPEWG 1294
+ + WG
Sbjct: 770 EADCPEGRWG 779
>gi|122937283 6720455I24Rik homolog [Homo sapiens]
Length = 1413
Score = 384 bits (986), Expect = e-106
Identities = 219/659 (33%), Positives = 288/659 (43%), Gaps = 96/659 (14%)
Query: 472 CEADHNECLS-QPCHPGSTCLDLLAT----FHCLCPPGLEGQLCEVETNECASAPCLNHA 526
C + CL+ +PC G C+D T + C C G G+ C ++ NECAS PC N
Sbjct: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
Query: 527 DCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRC 586
C +N F+C C GF G CE C + C +GGQCQ + G+ C C G+ G C
Sbjct: 325 TCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAAC 384
Query: 587 QTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCE-----VP-LCAPNLCQPKQIC 640
+ +VD+C DPC G SC+DL G + CLC F G CE VP C C C
Sbjct: 385 EMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC 444
Query: 641 KDQKDKANCLCPDGSPGCAPPE---DNCTCHHGH----CQRSSCVCDVGWTGPECEAEL- 692
D C CP+G G E D+C C +G + C C +G+ G CE E+
Sbjct: 445 VDADQGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQCPLGFFGLLCEFEIT 504
Query: 693 -------------------GG-------------------CISAPCAHGGTCYPQPSGYN 714
GG C S PC +GG+C Y
Sbjct: 505 AMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCFNGGSCDAHDDSYT 564
Query: 715 CTCPTGYTGPTCSEEMT-ACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTST-DYCV 772
C CP G+ G C + C SGPC NGG+C + G Y+C+CP TG C+ D C
Sbjct: 565 CECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCA 624
Query: 773 SAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPS-CADSPCRNRATCQDSPQGPRCL 831
S PC NGGTC + G + C C GF G CE + PS C SPC N TC+D C
Sbjct: 625 SGPCHNGGTCFHYIGKYKCDCPPGFSGRHCE--IAPSPCFRSPCVNGGTCEDRDTDFFCH 682
Query: 832 CPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQG------------------ 873
C GY G CQ +D C +++ G + L
Sbjct: 683 CQAGYMGRRCQAEVD-CGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQP 741
Query: 874 ---WTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDH 930
W+ P L + C+ S C +GG C D Y C C G++G+ C+
Sbjct: 742 HGVWSEPPQCLEIDECR----------SQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELE 791
Query: 931 VNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGF 990
+ C + PC+NG +C P Y+C+C G+ G +C E+DAC S PC + G C G +
Sbjct: 792 RDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAY 851
Query: 991 HCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDP 1049
C CP F G CE D C PC G C + + C C G+TG+ C E+ P
Sbjct: 852 LCVCPESFFGYHCETVSDPCFSSPC--GGRGYCLASNGSHSCTCKVGYTGEDCAKELFP 908
Score = 380 bits (976), Expect = e-105
Identities = 220/654 (33%), Positives = 290/654 (44%), Gaps = 65/654 (9%)
Query: 204 PCPKGTSCHNTL----GSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTF 259
PC G C + S+ C C G G RC L C + C NGGTC ++F
Sbjct: 277 PCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCT---HGINSF 333
Query: 260 HLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECE 319
C CP GF GP CE C + +CQ+GG CQ + C+C +TG C DVD+C
Sbjct: 334 R-CQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCS 392
Query: 320 TQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEEN----LDDCIAATCAPGSTCIDRVG 375
P C NGG+C + G++ C+C + G CE D C++A C G TC+D
Sbjct: 393 ---PDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQ 449
Query: 376 SFSCLCPPGRTGLLCH--LEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDL 433
+ C CP G GL C + D C C +C +TLC C G+ G C ++
Sbjct: 450 GYVCECPEGFMGLDCRERVPDDC---ECRNGGRCLG---ANTTLCQCPLGFFGLLCEFEI 503
Query: 434 DE--CLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCL 491
C M Q C GG C+ GS+ C+C + S + C S PC G +C
Sbjct: 504 TAMPCNMNTQ----CPDGGYCMEHGGSYLCVCHTDHNASHSLP--SPCDSDPCFNGGSCD 557
Query: 492 DLLATFHCLCPPGLEGQLCE-VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCE- 549
++ C CP G G+ CE + C+S PC N C + + C C F+G CE
Sbjct: 558 AHDDSYTCECPRGFHGKHCEKARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEI 617
Query: 550 EDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPG 609
D C S PC NGG C G + C C PGF G C+ C PC G +C D
Sbjct: 618 GKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDT 677
Query: 610 AFFCLCPSGFTGQLCEVPL-CAP-----------NLCQPKQICKDQKDKANCL------- 650
FFC C +G+ G+ C+ + C P N + + D+ L
Sbjct: 678 DFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIR 737
Query: 651 -CPDGSPGCAPPE----DNCTC----HHGHCQRSS----CVCDVGWTGPECEAELGGCIS 697
C PP+ D C H G CQ C+C G+ G CE E C +
Sbjct: 738 VCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECRA 797
Query: 698 APCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPP 757
PC +GG+C P Y C CP G+ G C E+ AC S PC +GG C G Y C CP
Sbjct: 798 HPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCPE 857
Query: 758 SHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCA 811
S G C+T +D C S+PC G C+ G+ SC C +G+ G C +L P A
Sbjct: 858 SFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKELFPPTA 911
Score = 379 bits (972), Expect = e-104
Identities = 228/669 (34%), Positives = 298/669 (44%), Gaps = 73/669 (10%)
Query: 510 CEVETNEC-ASAPCLNHADC-HDLLNG---FQCICLPGFSGTRCEEDIDECRSSPCANGG 564
C T+ C A PCLN C D + G + C CL GF+G RC D++EC S PC NGG
Sbjct: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGG 324
Query: 565 QCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLC 624
C +F C+C GF GP C+T C + C G C G+ C+C +G+TG C
Sbjct: 325 TCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGYTGAAC 384
Query: 625 EVPL--CAPNLCQPKQICKDQKDKANCLCPDGSPGCA------PPEDNCT---CHHGHC- 672
E+ + C+P+ C C D CLC + G P D C CH+G
Sbjct: 385 EMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTC 444
Query: 673 ----QRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSE 728
Q C C G+ G +C + C +GG C + C CP G+ G C
Sbjct: 445 VDADQGYVCECPEGFMGLDCRERVPD--DCECRNGGRCLGANTTL-CQCPLGFFGLLCEF 501
Query: 729 EMTA--CHSGP-CLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNR 785
E+TA C+ C +GG C G Y C C H S C S PCFNGG+C
Sbjct: 502 EITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSP--CDSDPCFNGGSCDAH 559
Query: 786 PGTFSCLCAMGFQGPRCEGKLRPS-CADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQT- 843
+++C C GF G CE K RP C+ PCRN TC+++ C CP +TG C+
Sbjct: 560 DDSYTCECPRGFHGKHCE-KARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIG 618
Query: 844 LMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHN 903
D CA PC C + C C G++G C + S C + S C N
Sbjct: 619 KPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFR----------SPCVN 668
Query: 904 GGLCVDSGPSYFCHCPPGFQGSLCQDHVN---PCESR-----------------PCQNGA 943
GG C D +FCHC G+ G CQ V+ P E + C G
Sbjct: 669 GGTCEDRDTDFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGY 728
Query: 944 TCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRC 1003
+ A +CQ + E+D C+SQPC + G+C + G+ C C G+ G C
Sbjct: 729 SLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHC 788
Query: 1004 EGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEA 1063
E + DEC PC G+ C +L A+ C+C G G CE E+D C S PC HGG CE+
Sbjct: 789 ELERDECRAHPCRNGGS--CRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCES 846
Query: 1064 TAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGP 1123
G+ ++C CP+ F G C + C C G CL S C C GY G
Sbjct: 847 GGGA---YLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLAS---NGSHSCTCKVGYTGE 900
Query: 1124 DC---LTPP 1129
DC L PP
Sbjct: 901 DCAKELFPP 909
Score = 365 bits (937), Expect = e-100
Identities = 218/650 (33%), Positives = 285/650 (43%), Gaps = 67/650 (10%)
Query: 127 CSKRGRCHIQA-SGRPQ--CSCMPGWTGEQCQLR-DFCSANPCVNGGVCLATYPQIQCHC 182
C G+C +G P CSC+ G+TG +C L + C++ PC NGG C +C C
Sbjct: 278 CLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGINSFRCQC 337
Query: 183 PPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRG 242
P GF G CE + C D C G C GS C+C G G CE+ C P
Sbjct: 338 PAGFGGPTCETAQSPC--DTKECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDP 395
Query: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVN----PDNCVSHQCQNGGTCQDGLDTY 298
C NGG+C + + CLC F G CE PD C+S C NGGTC D Y
Sbjct: 396 CLNGGSCVDLVGN----YTCLCAEPFKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGY 451
Query: 299 TCLCPETWTGWDCSEDV-DECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLD 357
C CPE + G DC E V D+CE CRNGG C A + C C G+ G CE +
Sbjct: 452 VCECPEGFMGLDCRERVPDDCE------CRNGGRCL-GANTTLCQCPLGFFGLLCEFEIT 504
Query: 358 --DCIAAT-CAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTG 414
C T C G C++ GS+ C+C L C S PC C +
Sbjct: 505 AMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNA-SHSLPSPCDSDPCFNGGSCDAH--DD 561
Query: 415 STLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCE- 473
S C C G+ G C + + PC +GG+C G ++C CP +TG CE
Sbjct: 562 SYTCECPRGFHGKHCEKARPHLCSS----GPCRNGGTCKEAGGEYHCSCPYRFTGRHCEI 617
Query: 474 ADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLN 533
+ C S PCH G TC + + C CPPG G+ CE+ + C +PC+N C D
Sbjct: 618 GKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVNGGTCEDRDT 677
Query: 534 GFQCICLPGFSGTRCEEDID-----ECRSSPCANGGQCQDQPGAFHCK------------ 576
F C C G+ G RC+ ++D E + + G + C
Sbjct: 678 DFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIR 737
Query: 577 -CLP---GFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPL--CA 630
C P E P+C E+DEC S PC G SC D + CLC +G+ G CE+ C
Sbjct: 738 VCQPHGVWSEPPQC-LEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEGAHCELERDECR 796
Query: 631 PNLCQPKQICKDQKDKANCLCPDGSPG--CAPPEDNC---TCHH-GHCQRSS----CVCD 680
+ C+ C++ C CP G G C D C C H G C+ CVC
Sbjct: 797 AHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCESGGGAYLCVCP 856
Query: 681 VGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEM 730
+ G CE C S+PC G C ++CTC GYTG C++E+
Sbjct: 857 ESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKEL 906
Score = 350 bits (897), Expect = 1e-95
Identities = 214/672 (31%), Positives = 281/672 (41%), Gaps = 97/672 (14%)
Query: 34 PCANGGTCLSLSLGQG---TCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGL 90
PC NGG C+ + TC C GF G C +Q CQNGG+C +
Sbjct: 277 PCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQNGGTCTHGIN----- 331
Query: 91 PSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWT 150
SF C C GF G C+ + PC C G+C ++ +G C C G+T
Sbjct: 332 ---------SFRCQCPAGFGGPTCETA-QSPCDTKECQHGGQCQVE-NGSAVCVCQAGYT 380
Query: 151 GEQCQLR-DFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERD----VNECFQDPGPC 205
G C++ D CS +PC+NGG C+ C C F+G CE + C PC
Sbjct: 381 GAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLS--APC 438
Query: 206 PKGTSCHNTLGSFQCLCPVGQEGPRCELRA-GPCPPRGCSNGGTCQLMPEKDSTFHLCLC 264
G +C + + C CP G G C R C C NGG C + LC C
Sbjct: 439 HNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCE---CRNGGRCL-----GANTTLCQC 490
Query: 265 PPGFIGPDCEVN---------------------------------------PDNCVSHQC 285
P GF G CE P C S C
Sbjct: 491 PLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPC 550
Query: 286 QNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVS 345
NGG+C D+YTC CP + G C + + GP CRNGGTC+ + G +HC C
Sbjct: 551 FNGGSCDAHDDSYTCECPRGFHGKHCEKARPHLCSSGP--CRNGGTCKEAGGEYHCSCPY 608
Query: 346 GWGGTSCEENL-DDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDM-CLSQPCHG 403
+ G CE D C + C G TC +G + C CPPG +G C + C PC
Sbjct: 609 RFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPGFSGRHCEIAPSPCFRSPCVN 668
Query: 404 DAQCSTNPLTGSTLCLCQPGYSGPTCHQDLD--------ECLMAQQGPS-------PCEH 448
C C CQ GY G C ++D + G C+
Sbjct: 669 GGTCEDRDT--DFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAVALYACDR 726
Query: 449 GGSCLNTPGSFNCLCPPGYTGSRCEA-DHNECLSQPCHPGSTCLDLLATFHCLCPPGLEG 507
G S L+ P P G + + +EC SQPC G +C D +A + CLC G EG
Sbjct: 727 GYS-LSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTGYEG 785
Query: 508 QLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQ 567
CE+E +EC + PC N C +L + C C GF G CE ++D C SSPC +GG+C+
Sbjct: 786 AHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDACDSSPCQHGGRCE 845
Query: 568 DQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVP 627
GA+ C C F G C+T D C S PC CL G+ C C G+TG+ C
Sbjct: 846 SGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKVGYTGEDCAKE 905
Query: 628 LCAPNLCQPKQI 639
L P + +++
Sbjct: 906 LFPPTALKMERV 917
Score = 320 bits (820), Expect = 9e-87
Identities = 218/701 (31%), Positives = 278/701 (39%), Gaps = 144/701 (20%)
Query: 586 CQTEVDECLS-DPCPVGASCLD--LPG--AFFCLCPSGFTGQLCEVPL--CAPNLCQPKQ 638
C CL+ PC G C+D + G ++ C C SGFTG+ C + + CA CQ
Sbjct: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQ--- 321
Query: 639 ICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISA 698
+ TC HG C C G+ GP CE C +
Sbjct: 322 ------------------------NGGTCTHG-INSFRCQCPAGFGGPTCETAQSPCDTK 356
Query: 699 PCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPS 758
C HGG C + C C GYTG C ++ C PCLNGGSC G Y C C
Sbjct: 357 ECQHGGQCQVENGSAVCVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEP 416
Query: 759 HTGPQCQTST----DYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSP 814
G +C+T D C+SAPC NGGTCV+ + C C GF G C ++ C
Sbjct: 417 FKGLRCETGDHPVPDACLSAPCHNGGTCVDADQGYVCECPEGFMGLDCRERVPDDCE--- 473
Query: 815 CRNRATCQDSPQGPRCLCPTGYTGGSCQ---TLMDLCAQKPCPRNSHCLQTGPSFHCLCL 871
CRN C + C CP G+ G C+ T M CP +C++ G S+ C+C
Sbjct: 474 CRNGGRCLGA-NTTLCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCH 532
Query: 872 QGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQD-H 930
+LP S C S C NGG C SY C CP GF G C+
Sbjct: 533 TDHNASH-SLP-SPCD----------SDPCFNGGSCDAHDDSYTCECPRGFHGKHCEKAR 580
Query: 931 VNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCS-KELDACQSQPCHNHGTCTPKPGG 989
+ C S PC+NG TC Y C C + G++C + D+C S PCHN GTC G
Sbjct: 581 PHLCSSGPCRNGGTCKEAGGEYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGK 640
Query: 990 FHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQ---------------- 1033
+ C CPPGF G CE C PC GT C F+C
Sbjct: 641 YKCDCPPGFSGRHCEIAPSPCFRSPCVNGGT--CEDRDTDFFCHCQAGYMGRRCQAEVDC 698
Query: 1034 -------------------------CLPGHT-------------GQWCE----VEIDPCH 1051
C G++ G W E +EID C
Sbjct: 699 GPPEEVKHATLRFNGTRLGAVALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECR 758
Query: 1052 SQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFP 1111
SQPC HGG+C+ G++C C G+EG C C H C +GG C P
Sbjct: 759 SQPCLHGGSCQDRVA---GYLCLCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYV- 814
Query: 1112 PRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQ 1171
C C +G+ G C T C SPC + G C GG + C CP S G C+
Sbjct: 815 --CRCPAGFVGVHCETEV--DACDS-SPCQHGGRCES----GGGAYLCVCPESFFGYHCE 865
Query: 1172 KPG----AKGCEGR----SGDGACDAGCSGPGGNWDGGDCS 1204
+ C GR + +G+ C + G DC+
Sbjct: 866 TVSDPCFSSPCGGRGYCLASNGSHSCTCK---VGYTGEDCA 903
Score = 264 bits (675), Expect = 6e-70
Identities = 172/550 (31%), Positives = 223/550 (40%), Gaps = 105/550 (19%)
Query: 32 PEPCANGGTCLSLSLGQGTCQCAPGFLGETCQ-----FPDPCQNAQLCQNGGSCQALLPA 86
P+PC NGG+C+ L +G TC CA F G C+ PD C +A C NGG+C + A
Sbjct: 393 PDPCLNGGSCVDL-VGNYTCLCAEPFKGLRCETGDHPVPDACLSAP-CHNGGTC---VDA 447
Query: 87 PLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCM 146
G ++C C GF G C+ ++ D C C GRC + C C
Sbjct: 448 DQG-----------YVCECPEGFMGLDCRERVPDDCE---CRNGGRC--LGANTTLCQCP 491
Query: 147 PGWTGEQCQ----------------------------------------LRDFCSANPCV 166
G+ G C+ L C ++PC
Sbjct: 492 LGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPSPCDSDPCF 551
Query: 167 NGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQ 226
NGG C A C CP GF G CE+ GPC G +C G + C CP
Sbjct: 552 NGGSCDAHDDSYTCECPRGFHGKHCEK-ARPHLCSSGPCRNGGTCKEAGGEYHCSCPYRF 610
Query: 227 EGPRCEL-RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQC 285
G CE+ + C C NGGTC K + C CPPGF G CE+ P C C
Sbjct: 611 TGRHCEIGKPDSCASGPCHNGGTCFHYIGK----YKCDCPPGFSGRHCEIAPSPCFRSPC 666
Query: 286 QNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPH------CRNGGTCQNSAGSF 339
NGGTC+D + C C + G C +VD C GPP R GT + +
Sbjct: 667 VNGGTCEDRDTDFFCHCQAGYMGRRCQAEVD-C---GPPEEVKHATLRFNGTRLGAVALY 722
Query: 340 HC-------------VCV--SGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPG 384
C VC W +D+C + C G +C DRV + CLC G
Sbjct: 723 ACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGYLCLCSTG 782
Query: 385 RTGLLCHLE-DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGP 443
G C LE D C + PC C P G+ +C C G+ G C ++D C
Sbjct: 783 YEGAHCELERDECRAHPCRNGGSCRNLP--GAYVCRCPAGFVGVHCETEVDAC-----DS 835
Query: 444 SPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPP 503
SPC+HGG C + G++ C+CP + G CE + C S PC CL + C C
Sbjct: 836 SPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCLASNGSHSCTCKV 895
Query: 504 GLEGQLCEVE 513
G G+ C E
Sbjct: 896 GYTGEDCAKE 905
Score = 191 bits (484), Expect = 8e-48
Identities = 142/470 (30%), Positives = 181/470 (38%), Gaps = 87/470 (18%)
Query: 839 GSCQTLMDLC-AQKPCPRNSHCLQ---TG-PSFHCLCLQGWTGPLCNLPLSSCQKAALSQ 893
G C +C A +PC C+ TG PS+ C CL G+TG C+L ++ C
Sbjct: 263 GGCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNEC------- 315
Query: 894 GIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYL 953
S C NGG C S+ C CP GF G C+ +PC+++ CQ+G C + +
Sbjct: 316 ---ASQPCQNGGTCTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSAV 372
Query: 954 CQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCE-GD---VDE 1009
C C GY G C ++D C PC N G+C G + C C F GLRCE GD D
Sbjct: 373 CVCQAGYTGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDA 432
Query: 1010 CLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI-DPCHSQPCFHGGTCEATAGSP 1068
CL PCH GT C + C+C G G C + D C C +GG C +
Sbjct: 433 CLSAPCHNGGT--CVDADQGYVCECPEGFMGLDCRERVPDDCE---CRNGGRCLGANTT- 486
Query: 1069 LGFICHCPKGFEGPTCSHR--APSCGFH-HCHHGGLC--------------------LPS 1105
+C CP GF G C A C + C GG C LPS
Sbjct: 487 ---LCQCPLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCVCHTDHNASHSLPS 543
Query: 1106 PKPGFPP-------------RCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGL 1152
P P C C G+ G C P C PC G+C E G
Sbjct: 544 PCDSDPCFNGGSCDAHDDSYTCECPRGFHGKHC-EKARPHLCSS-GPCRNGGTCKEAGG- 600
Query: 1153 GGPGFRCSCPHSSPGPRCQ--KPGAKGCEGRSGDGAC-----DAGCSGPGGNWDGGDCSL 1205
+ CSCP+ G C+ KP + G C C P G + G C +
Sbjct: 601 ---EYHCSCPYRFTGRHCEIGKPDSCASGPCHNGGTCFHYIGKYKCDCPPG-FSGRHCEI 656
Query: 1206 GVPDPW--KGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCETPPACTP 1253
P P C + C D CH Q + G C+ C P
Sbjct: 657 -APSPCFRSPCVNGGTCEDRDTDFFCHCQAG-----YMGRRCQAEVDCGP 700
Score = 145 bits (366), Expect = 4e-34
Identities = 111/360 (30%), Positives = 145/360 (40%), Gaps = 57/360 (15%)
Query: 965 CSKELDACQS-QPCHNHGTC-----TPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPT 1018
C C + +PC N G C T P + C+C GF G RC DV+EC QPC
Sbjct: 265 CGHTTSVCLALRPCLNGGKCIDDCVTGNPS-YTCSCLSGFTGRRCHLDVNECASQPCQNG 323
Query: 1019 GTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKG 1078
GT C N+F CQC G G CE PC ++ C HGG C+ GS +C C G
Sbjct: 324 GT--CTHGINSFRCQCPAGFGGPTCETAQSPCDTKECQHGGQCQVENGSA---VCVCQAG 378
Query: 1079 FEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTP--PAPKGCGP 1136
+ G C C C +GG C+ C C + G C T P P C
Sbjct: 379 YTGAACEMDVDDCSPDPCLNGGSCVDLVGNY---TCLCAEPFKGLRCETGDHPVPDAC-L 434
Query: 1137 PSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGD---GACDAGCSG 1193
+PC G+C + G+ C CP G C++ CE R+G GA C
Sbjct: 435 SAPCHNGGTCVDAD----QGYVCECPEGFMGLDCRERVPDDCECRNGGRCLGANTTLCQC 490
Query: 1194 PGGNWD--------GGDCSLGVPDPWKG-CPSHSRCWLLFRDGQCHPQ----------CD 1234
P G + C++ P G C H +L CH CD
Sbjct: 491 PLGFFGLLCEFEITAMPCNMNTQCPDGGYCMEHGGSYLCV----CHTDHNASHSLPSPCD 546
Query: 1235 SEECLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKG----CNTAECGWDGGDCRPEDGD 1290
S+ C F+G C+ A +Y C FH HCEK C++ C +GG C+ G+
Sbjct: 547 SDPC-FNGGSCD---AHDDSYTCECPRGFHGKHCEKARPHLCSSGPCR-NGGTCKEAGGE 601
Score = 129 bits (324), Expect = 3e-29
Identities = 85/251 (33%), Positives = 106/251 (42%), Gaps = 18/251 (7%)
Query: 31 FPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQF------PDPCQNAQLCQNGGSCQALL 84
F PC NGGTC C C G++G CQ P+ ++A L NG A+
Sbjct: 662 FRSPCVNGGTCEDRDT-DFFCHCQAGYMGRRCQAEVDCGPPEEVKHATLRFNGTRLGAV- 719
Query: 85 PAPLGLPSSPSPLTPSFLCTCLP-GFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQC 143
A S PS + C P G E Q D C C G C + +G C
Sbjct: 720 -ALYACDRGYSLSAPSRIRVCQPHGVWSEPPQCLEIDECRSQPCLHGGSCQDRVAGY-LC 777
Query: 144 SCMPGWTGEQCQL-RDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDP 202
C G+ G C+L RD C A+PC NGG C C CP GF G CE +V+ C D
Sbjct: 778 LCSTGYEGAHCELERDECRAHPCRNGGSCRNLPGAYVCRCPAGFVGVHCETEVDAC--DS 835
Query: 203 GPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLC 262
PC G C + G++ C+CP G CE + PC C G C + H C
Sbjct: 836 SPCQHGGRCESGGGAYLCVCPESFFGYHCETVSDPCFSSPCGGRGYCL----ASNGSHSC 891
Query: 263 LCPPGFIGPDC 273
C G+ G DC
Sbjct: 892 TCKVGYTGEDC 902
Score = 46.2 bits (108), Expect = 3e-04
Identities = 20/48 (41%), Positives = 24/48 (50%), Gaps = 3/48 (6%)
Query: 160 CSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPK 207
CS NPC NGG C+ C C PGF+G CE C + PC +
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL---ACIKVSRPCTR 1355
Score = 45.4 bits (106), Expect = 5e-04
Identities = 50/190 (26%), Positives = 64/190 (33%), Gaps = 39/190 (20%)
Query: 1133 GCGPPS-------PCLYNGSCSETTGLGGPGFRCSCPHSSPGPRC----QKPGAKGCEGR 1181
GCG + PCL G C + G P + CSC G RC + ++ C+
Sbjct: 264 GCGHTTSVCLALRPCLNGGKCIDDCVTGNPSYTCSCLSGFTGRRCHLDVNECASQPCQ-- 321
Query: 1182 SGDGACDAG-----CSGPGGNWDGGDCSLG-VPDPWKGCPSHSRCWLLFRDGQCHPQC-- 1233
G C G C P G + G C P K C +C + C Q
Sbjct: 322 -NGGTCTHGINSFRCQCPAG-FGGPTCETAQSPCDTKECQHGGQCQVENGSAVCVCQAGY 379
Query: 1234 DSEECLFDGYDCETPP-----ACTPAYDQY---CHDHFHNGHCEKG-------CNTAECG 1278
C D DC P +C Y C + F CE G C +A C
Sbjct: 380 TGAACEMDVDDCSPDPCLNGGSCVDLVGNYTCLCAEPFKGLRCETGDHPVPDACLSAPC- 438
Query: 1279 WDGGDCRPED 1288
+GG C D
Sbjct: 439 HNGGTCVDAD 448
Score = 45.1 bits (105), Expect = 7e-04
Identities = 19/46 (41%), Positives = 24/46 (52%), Gaps = 5/46 (10%)
Query: 934 CESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDAC--QSQPC 977
C PCQNG TC+ + C C PG+ G+ C AC S+PC
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL---ACIKVSRPC 1353
Score = 44.7 bits (104), Expect = 0.001
Identities = 17/33 (51%), Positives = 17/33 (51%)
Query: 972 CQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCE 1004
C PC N GTC P C C PGF G RCE
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
Score = 43.9 bits (102), Expect = 0.002
Identities = 20/47 (42%), Positives = 21/47 (44%)
Query: 757 PSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCE 803
P H C PC NGGTCV SC C GF+G RCE
Sbjct: 1297 PEHGSKDIGNVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE 1343
Score = 43.1 bits (100), Expect = 0.003
Identities = 19/44 (43%), Positives = 24/44 (54%), Gaps = 1/44 (2%)
Query: 555 CRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPC 598
C +PC NGG C A C C PGF+G RC+ + +S PC
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
Score = 42.0 bits (97), Expect = 0.006
Identities = 22/60 (36%), Positives = 26/60 (43%)
Query: 252 MPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDC 311
M E L L P D P NC + CQNGGTC G D ++C C + G C
Sbjct: 1283 MEEAPKRVSLALQLPEHGSKDIGNVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRC 1342
Score = 40.8 bits (94), Expect = 0.013
Identities = 17/44 (38%), Positives = 22/44 (50%), Gaps = 1/44 (2%)
Query: 733 CHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPC 776
C PC NGG+C P + C C P G +C+ + VS PC
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELAC-IKVSRPC 1353
Score = 40.4 bits (93), Expect = 0.018
Identities = 14/34 (41%), Positives = 18/34 (52%)
Query: 693 GGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTC 726
G C PC +GGTC P ++C C G+ G C
Sbjct: 1309 GNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRC 1342
Score = 40.0 bits (92), Expect = 0.023
Identities = 17/43 (39%), Positives = 27/43 (62%), Gaps = 5/43 (11%)
Query: 444 SPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECL--SQPC 484
+PC++GG+C+ + +C C PG+ G RCE C+ S+PC
Sbjct: 1314 NPCQNGGTCVPGADAHSCDCGPGFKGRRCEL---ACIKVSRPC 1353
Score = 38.5 bits (88), Expect = 0.067
Identities = 17/57 (29%), Positives = 28/57 (49%), Gaps = 1/57 (1%)
Query: 799 GPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPR 855
G + G + +C+++PC+N TC C C G+ G C+ L + +PC R
Sbjct: 1300 GSKDIGNVPGNCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCE-LACIKVSRPCTR 1355
Score = 38.5 bits (88), Expect = 0.067
Identities = 18/41 (43%), Positives = 22/41 (53%), Gaps = 5/41 (12%)
Query: 901 CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPC--ESRPC 939
C NGG CV ++ C C PGF+G C+ C SRPC
Sbjct: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCE---LACIKVSRPC 1353
Score = 38.1 bits (87), Expect = 0.087
Identities = 19/40 (47%), Positives = 22/40 (55%), Gaps = 4/40 (10%)
Query: 236 GPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEV 275
G C C NGGTC +P D+ H C C PGF G CE+
Sbjct: 1309 GNCSENPCQNGGTC--VPGADA--HSCDCGPGFKGRRCEL 1344
Score = 37.4 bits (85), Expect = 0.15
Identities = 16/44 (36%), Positives = 22/44 (50%)
Query: 358 DCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPC 401
+C C G TC+ + SC C PG G C L + +S+PC
Sbjct: 1310 NCSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPC 1353
Score = 36.2 bits (82), Expect = 0.33
Identities = 14/30 (46%), Positives = 17/30 (56%), Gaps = 1/30 (3%)
Query: 34 PCANGGTCLSLSLGQGTCQCAPGFLGETCQ 63
PC NGGTC+ +C C PGF G C+
Sbjct: 1315 PCQNGGTCVP-GADAHSCDCGPGFKGRRCE 1343
Score = 35.8 bits (81), Expect = 0.43
Identities = 16/44 (36%), Positives = 21/44 (47%), Gaps = 1/44 (2%)
Query: 479 CLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPC 522
C PC G TC+ C C PG +G+ CE+ + S PC
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIK-VSRPC 1353
Score = 35.4 bits (80), Expect = 0.57
Identities = 19/61 (31%), Positives = 23/61 (37%), Gaps = 11/61 (18%)
Query: 517 CASAPCLNHADCHDLLNGFQCICLPGFSGTRCE-----------EDIDECRSSPCANGGQ 565
C+ PC N C + C C PGF G RCE E ++ P GG
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGGV 1370
Query: 566 C 566
C
Sbjct: 1371 C 1371
Score = 34.3 bits (77), Expect = 1.3
Identities = 18/69 (26%), Positives = 27/69 (39%), Gaps = 13/69 (18%)
Query: 122 CPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSANPCV------------NGG 169
C + C G C + + C C PG+ G +C+L + PC GG
Sbjct: 1311 CSENPCQNGGTC-VPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEGG 1369
Query: 170 VCLATYPQI 178
VC Y ++
Sbjct: 1370 VCHHVYKRV 1378
Score = 34.3 bits (77), Expect = 1.3
Identities = 23/84 (27%), Positives = 33/84 (39%), Gaps = 16/84 (19%)
Query: 326 CRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGR 385
C+NGGTC A + C C G+ G CE C S R+ S + P
Sbjct: 1316 CQNGGTCVPGADAHSCDCGPGFKGRRCE--------LACIKVSRPCTRLFSETKAFPVWE 1367
Query: 386 TGLLCHL--------EDMCLSQPC 401
G+ H+ +D+C + C
Sbjct: 1368 GGVCHHVYKRVYRVHQDICFKESC 1391
Score = 33.9 bits (76), Expect = 1.6
Identities = 22/71 (30%), Positives = 27/71 (38%), Gaps = 24/71 (33%)
Query: 74 CQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQ---AKLEDPCPPSFCSKR 130
CQNGG+C P + C C PGF G RC+ K+ PC F +
Sbjct: 1316 CQNGGTCV--------------PGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETK 1361
Query: 131 -------GRCH 134
G CH
Sbjct: 1362 AFPVWEGGVCH 1372
Score = 33.1 bits (74), Expect = 2.8
Identities = 21/63 (33%), Positives = 27/63 (42%), Gaps = 13/63 (20%)
Query: 1010 CLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI----DPC-------HSQPCFHG 1058
C + PC GT C A+A C C PG G+ CE+ PC + P + G
Sbjct: 1311 CSENPCQNGGT--CVPGADAHSCDCGPGFKGRRCELACIKVSRPCTRLFSETKAFPVWEG 1368
Query: 1059 GTC 1061
G C
Sbjct: 1369 GVC 1371
Score = 32.7 bits (73), Expect = 3.7
Identities = 13/34 (38%), Positives = 18/34 (52%)
Query: 593 CLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEV 626
C +PC G +C+ A C C GF G+ CE+
Sbjct: 1311 CSENPCQNGGTCVPGADAHSCDCGPGFKGRRCEL 1344
>gi|41327708 crumbs homolog 1 precursor [Homo sapiens]
Length = 1406
Score = 354 bits (908), Expect = 5e-97
Identities = 184/488 (37%), Positives = 227/488 (46%), Gaps = 69/488 (14%)
Query: 352 CEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGL---LCHLEDMCLSQPCHGDAQCS 408
C +N C++ +C STC D C C L +++D C S PC G A C
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 409 TNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT 468
P S LC C PGYSG C + C G + C+HGG C P C+CP GY
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIGSC-----GKNSCQHGGICHQDPIYPVCICPAGYA 141
Query: 469 GSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADC 528
G CE DH+EC S PC G+ C D + + C C PG +G+ C++E +ECAS PC N A C
Sbjct: 142 GRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATC 201
Query: 529 HDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQT 588
+ + + CIC +SG CE +IDEC S PC NG CQD GA+ C C PGF G C+
Sbjct: 202 LNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCEL 261
Query: 589 EVDECLSDPCPVGASCLDLPGAFFCLCP-SGFTGQLCE--VPLCAPNLCQPKQICKDQKD 645
DEC S PC G C+D + C C SGFTG CE +PLC C C+D
Sbjct: 262 NTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDS-- 319
Query: 646 KANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGT 705
DN TCH C G+TG +CE +L C S PC G
Sbjct: 320 ----------------VDNYTCH----------CWPGYTGAQCEIDLNECNSNPCQSNGE 353
Query: 706 C--------------------YPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCN 745
C Y + SGY C C G+TG C E++ C S PC NGG+C
Sbjct: 354 CVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCE 413
Query: 746 PSPGGYYCTCP------PSHTGPQCQTSTDYCVSAPCFNGGTCV----NRPGTFSCLCAM 795
PG Y C CP + G C C C N GTC+ + FSCLC
Sbjct: 414 NLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPS 473
Query: 796 GFQGPRCE 803
G+ G CE
Sbjct: 474 GYTGSLCE 481
Score = 320 bits (821), Expect = 7e-87
Identities = 167/480 (34%), Positives = 217/480 (45%), Gaps = 65/480 (13%)
Query: 396 CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT 455
CLS C ++ C C C D C +PC+ +C+NT
Sbjct: 34 CLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFS-----NPCQGSATCVNT 88
Query: 456 PG--SFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVE 513
PG SF C CPPGY+G+ CE C C G C C+CP G G+ CE++
Sbjct: 89 PGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGRFCEID 148
Query: 514 TNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAF 573
+ECAS+PC N A C D ++G+ C C+PG+ G C+ ++DEC S PC N C ++ G +
Sbjct: 149 HDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATCLNEIGRY 208
Query: 574 HCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPL--CAP 631
C C + G C+ E+DEC S PC GA+C D GA+FC C GF G CE+ CA
Sbjct: 209 TCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTDECAS 268
Query: 632 NLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAE 691
C +C D +++ +C NCT G+TG CE
Sbjct: 269 QPCLHGGLCVDGENRYSC--------------NCT-------------GSGFTGTHCETL 301
Query: 692 LGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCN------ 745
+ C S PC + TC Y C C GYTG C ++ C+S PC + G C
Sbjct: 302 MPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEK 361
Query: 746 --------PSP------GGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSC 791
PS GY C C P TG C+ + C S PC NGGTC N PG ++C
Sbjct: 362 QYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTC 421
Query: 792 LCAMG-----FQGPRCEGKLRPSCADSPCRNRATC----QDSPQGPRCLCPTGYTGGSCQ 842
C F G R + C C N TC QD G CLCP+GYTG C+
Sbjct: 422 HCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCE 481
Score = 313 bits (801), Expect = 1e-84
Identities = 159/470 (33%), Positives = 225/470 (47%), Gaps = 48/470 (10%)
Query: 191 CERDVNECFQDPGPCPKGTSCHNTLGSFQCLCP--VGQEGPRCELRAGPCPPRGCSNGGT 248
C ++ C + C ++C + C C C+ PC C T
Sbjct: 27 CNKNNTRCLSNS--CQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSAT 84
Query: 249 CQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTG 308
C P + S LC CPPG+ G CE +C + CQ+GG C C+CP + G
Sbjct: 85 CVNTPGERS--FLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAG 142
Query: 309 WDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGS 368
C D DEC + C+NG CQ+ + C CV G+ G C+ +D+C + C +
Sbjct: 143 RFCEIDHDECASSP---CQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEA 199
Query: 369 TCIDRVGSFSCLCPPGRTGLLCHLE-DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGP 427
TC++ +G ++C+CP +G+ C LE D C SQPC A C G+ C C PG+ G
Sbjct: 200 TCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQD--ALGAYFCDCAPGFLGD 257
Query: 428 TCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCP-PGYTGSRCEADHNECLSQPCHP 486
C + DEC PC HGG C++ ++C C G+TG+ CE C S+PCH
Sbjct: 258 HCELNTDEC-----ASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHN 312
Query: 487 GSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDL--------------- 531
+TC D + + C C PG G CE++ NEC S PC ++ +C +L
Sbjct: 313 NATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSS 372
Query: 532 -----LNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKC------LPG 580
+G+ CIC PGF+G CEED++EC S+PC NGG C++ PG + C C
Sbjct: 373 FSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTF 432
Query: 581 FEGPRCQTEVDECLSDPCPVGASCL----DLPGAFFCLCPSGFTGQLCEV 626
+ G C + C C +C+ D F CLCPSG+TG LCE+
Sbjct: 433 YGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
Score = 306 bits (785), Expect = 1e-82
Identities = 171/496 (34%), Positives = 228/496 (45%), Gaps = 64/496 (12%)
Query: 273 CEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGW--DCSEDVDECETQGPPHCRNGG 330
C N C+S+ CQN TC+D C C +T DC D C + C+
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSN---PCQGSA 83
Query: 331 TCQNSAG--SFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGL 388
TC N+ G SF C C G+ GT CE + C +C G C C+CP G G
Sbjct: 84 TCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYAGR 143
Query: 389 LCHLE-DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCE 447
C ++ D C S PC A C + + G + C C PGY G C ++DEC PC+
Sbjct: 144 FCEIDHDECASSPCQNGAVCQ-DGIDGYS-CFCVPGYQGRHCDLEVDEC-----ASDPCK 196
Query: 448 HGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEG 507
+ +CLN G + C+CP Y+G CE + +EC SQPC G+TC D L + C C PG G
Sbjct: 197 NEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLG 256
Query: 508 QLCEVETNECASAPCLNHADCHDLLNGFQCICL-PGFSGTRCEEDIDECRSSPCANGGQC 566
CE+ T+ECAS PCL+ C D N + C C GF+GT CE + C S PC N C
Sbjct: 257 DHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATC 316
Query: 567 QDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLD------------LPGAF--- 611
+D + C C PG+ G +C+ +++EC S+PC C++ LP +F
Sbjct: 317 EDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYH 376
Query: 612 -----FCLCPSGFTGQLCE--VPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDN 664
C+C GFTG CE V C+ N CQ C++ C C P DN
Sbjct: 377 EASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHC---------PFDN 427
Query: 665 CTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQ----PSGYNCTCPTG 720
+ + G +C L GC C + GTC P G++C CP+G
Sbjct: 428 -------------LSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSG 474
Query: 721 YTGPTCSEEMTACHSG 736
YTG C T G
Sbjct: 475 YTGSLCEIATTLSFEG 490
Score = 291 bits (746), Expect = 3e-78
Identities = 156/463 (33%), Positives = 211/463 (45%), Gaps = 50/463 (10%)
Query: 160 CSANPCVNGGVCLATYPQIQCHCPPGFEG--HACERDVNECFQDPGPCPKGTSCHNTLG- 216
C +N C N C C C C+ + CF +P C +C NT G
Sbjct: 34 CLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNP--CQGSATCVNTPGE 91
Query: 217 -SFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEV 275
SF C CP G G CE G C C +GG C +D + +C+CP G+ G CE+
Sbjct: 92 RSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICH----QDPIYPVCICPAGYAGRFCEI 147
Query: 276 NPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNS 335
+ D C S CQNG CQDG+D Y+C C + G C +VDEC + C+N TC N
Sbjct: 148 DHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASD---PCKNEATCLNE 204
Query: 336 AGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-D 394
G + C+C + G +CE +D+C + C G+TC D +G++ C C PG G C L D
Sbjct: 205 IGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCELNTD 264
Query: 395 MCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLN 454
C SQPC C S C G++G C E LM PC + +C +
Sbjct: 265 ECASQPCLHGGLCVDGENRYSCNC-TGSGFTGTHC-----ETLMPLCWSKPCHNNATCED 318
Query: 455 TPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLA--------------TFH-- 498
+ ++ C C PGYTG++CE D NEC S PC C++L + ++H
Sbjct: 319 SVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEA 378
Query: 499 ----CLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCIC------LPGFSGTRC 548
C+C PG G CE + NEC+S PC N C +L + C C + G C
Sbjct: 379 SGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDC 438
Query: 549 EEDIDECRSSPCANGGQC----QDQPGAFHCKCLPGFEGPRCQ 587
+ + C C N G C QD F C C G+ G C+
Sbjct: 439 SDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCE 481
Score = 283 bits (724), Expect = 1e-75
Identities = 152/486 (31%), Positives = 204/486 (41%), Gaps = 69/486 (14%)
Query: 629 CAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPEC 688
C N CQ CKD +C C D + +C
Sbjct: 34 CLSNSCQNNSTCKDFSKDNDCSCSDTANNL--------------------------DKDC 67
Query: 689 EAELGGCISAPCAHGGTCYPQPS--GYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNP 746
+ C S PC TC P + C CP GY+G C + +C C +GG C+
Sbjct: 68 DNMKDPCFSNPCQGSATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQ 127
Query: 747 SPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKL 806
P C CP + G C+ D C S+PC NG C + +SC C G+QG C+ ++
Sbjct: 128 DPIYPVCICPAGYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEV 187
Query: 807 RPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSF 866
CA PC+N ATC + C+CP Y+G +C+ +D C +PC + C ++
Sbjct: 188 -DECASDPCKNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAY 246
Query: 867 HCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCP-PGFQGS 925
C C G+ G C L C S C +GGLCVD Y C+C GF G+
Sbjct: 247 FCDCAPGFLGDHCELNTDEC----------ASQPCLHGGLCVDGENRYSCNCTGSGFTGT 296
Query: 926 LCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTP 985
C+ + C S+PC N ATC Y C C PGY G C +L+ C S PC ++G C
Sbjct: 297 HCETLMPLCWSKPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVE 356
Query: 986 --------------------KPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHS 1025
+ G+ C C PGF G+ CE DV+EC PC GT C +
Sbjct: 357 LSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGT--CEN 414
Query: 1026 LANAFYCQC------LPGHTGQWCEVEIDPCHSQPCFHGGTC-EATAGSPLGFICHCPKG 1078
L + C C + G+ C + C Q C + GTC GF C CP G
Sbjct: 415 LPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSG 474
Query: 1079 FEGPTC 1084
+ G C
Sbjct: 475 YTGSLC 480
Score = 278 bits (710), Expect = 5e-74
Identities = 155/483 (32%), Positives = 204/483 (42%), Gaps = 47/483 (9%)
Query: 726 CSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPS--HTGPQCQTSTDYCVSAPCFNGGTCV 783
C++ T C S C N +C C+C + + C D C S PC TCV
Sbjct: 27 CNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCV 86
Query: 784 NRPG--TFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSC 841
N PG +F C C G+ G CE + SC + C++ C P P C+CP GY G C
Sbjct: 87 NTPGERSFLCKCPPGYSGTICETTIG-SCGKNSCQHGGICHQDPIYPVCICPAGYAGRFC 145
Query: 842 QTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLC 901
+ D CA PC + C + C C+ G+ G C+L + C S C
Sbjct: 146 EIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDEC----------ASDPC 195
Query: 902 HNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYD 961
N C++ Y C CP + G C+ ++ C S+PC NGATC Y C CAPG+
Sbjct: 196 KNEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFL 255
Query: 962 GQNCSKELDACQSQPCHNHGTCTPKPGGFHCACP-PGFVGLRCEGDVDECLDQPCHPTGT 1020
G +C D C SQPC + G C + C C GF G CE + C +PCH
Sbjct: 256 GDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCH--NN 313
Query: 1021 AACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATA---------GSPL-- 1069
A C + + C C PG+TG CE++++ C+S PC G C + G P
Sbjct: 314 ATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSF 373
Query: 1070 ------GFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCAC------L 1117
G++C C GF G C C + C +GG C P C C
Sbjct: 374 SYHEASGYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNY---TCHCPFDNLSR 430
Query: 1118 SGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKG 1177
+ YGG DC GC CL NG+C G GF C CP G C+
Sbjct: 431 TFYGGRDC--SDILLGC-THQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEIATTLS 487
Query: 1178 CEG 1180
EG
Sbjct: 488 FEG 490
Score = 255 bits (651), Expect = 3e-67
Identities = 152/480 (31%), Positives = 211/480 (43%), Gaps = 78/480 (16%)
Query: 35 CANGGTCLSLSLGQG-TCQCAPGFLGETCQ------FPDPCQNAQLCQNGGSCQALLPAP 87
C N TC S +C L + C F +PCQ + C N
Sbjct: 39 CQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGSATCVN----------- 87
Query: 88 LGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMP 147
+P SFLC C PG++G C+ + C + C G CH Q P C C
Sbjct: 88 -------TPGERSFLCKCPPGYSGTICETTIGS-CGKNSCQHGGICH-QDPIYPVCICPA 138
Query: 148 GWTGEQCQL-RDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCP 206
G+ G C++ D C+++PC NG VC C C PG++G C+ +V+EC D PC
Sbjct: 139 GYAGRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASD--PCK 196
Query: 207 KGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPP 266
+C N +G + C+CP G CEL C + C NG TCQ + C C P
Sbjct: 197 NEATCLNEIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQ----DALGAYFCDCAP 252
Query: 267 GFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPET-WTGWDCSEDVDECETQGPPH 325
GF+G CE+N D C S C +GG C DG + Y+C C + +TG C + C ++
Sbjct: 253 GFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSK---P 309
Query: 326 CRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCID------------- 372
C N TC++S ++ C C G+ G CE +L++C + C C++
Sbjct: 310 CHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGL 369
Query: 373 -------RVGSFSCLCPPGRTGLLCHLEDM--CLSQPCHGDAQCSTNPLTGSTLCLC--- 420
+ C+C PG TG+ C ED+ C S PC C P G+ C C
Sbjct: 370 PSSFSYHEASGYVCICQPGFTGIHCE-EDVNECSSNPCQNGGTCENLP--GNYTCHCPFD 426
Query: 421 ---QPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCL----NTPGSFNCLCPPGYTGSRCE 473
+ Y G C L C Q C + G+C+ + F+CLCP GYTGS CE
Sbjct: 427 NLSRTFYGGRDCSDILLGCTHQQ-----CLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCE 481
Score = 241 bits (616), Expect = 4e-63
Identities = 141/474 (29%), Positives = 197/474 (41%), Gaps = 64/474 (13%)
Query: 505 LEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSG--TRCEEDIDECRSSPCAN 562
++ C C S C N++ C D C C + C+ D C S+PC
Sbjct: 22 IKNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQG 81
Query: 563 GGQCQDQPG--AFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFT 620
C + PG +F CKC PG+ G C+T + C + C G C P C+CP+G+
Sbjct: 82 SATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGGICHQDPIYPVCICPAGYA 141
Query: 621 GQLCEV--PLCAPNLCQPKQICKDQKDKANCLCPDGSPG---------CA--PPEDNCTC 667
G+ CE+ CA + CQ +C+D D +C C G G CA P ++ TC
Sbjct: 142 GRFCEIDHDECASSPCQNGAVCQDGIDGYSCFCVPGYQGRHCDLEVDECASDPCKNEATC 201
Query: 668 HHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCS 727
+ R +C+C ++G CE E+ C S PC +G TC Y C C G+ G C
Sbjct: 202 LN-EIGRYTCICPHNYSGVNCELEIDECWSQPCLNGATCQDALGAYFCDCAPGFLGDHCE 260
Query: 728 EEMTACHSGPCLNGGSCNPSPGGYYCTCPPS-HTGPQCQTSTDYCVSAPCFNGGTCVNRP 786
C S PCL+GG C Y C C S TG C+T C S PC N TC +
Sbjct: 261 LNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWSKPCHNNATCEDSV 320
Query: 787 GTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQD--------------------SPQ 826
++C C G+ G +CE L C +PC++ C +
Sbjct: 321 DNYTCHCWPGYTGAQCEIDLN-ECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEAS 379
Query: 827 GPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSC 886
G C+C G+TG C+ ++ C+ PC C ++ C C P NL
Sbjct: 380 GYVCICQPGFTGIHCEEDVNECSSNPCQNGGTCENLPGNYTCHC------PFDNL----- 428
Query: 887 QKAALSQGIDVSSL--------CHNGGLCV----DSGPSYFCHCPPGFQGSLCQ 928
G D S + C N G C+ D + C CP G+ GSLC+
Sbjct: 429 -SRTFYGGRDCSDILLGCTHQQCLNNGTCIPHFQDGQHGFSCLCPSGYTGSLCE 481
Score = 173 bits (439), Expect = 1e-42
Identities = 79/192 (41%), Positives = 104/192 (54%), Gaps = 8/192 (4%)
Query: 444 SPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPP 503
+PC HGG+C + S++C CP G++G CE + +EC S PC G+ C D +A +HC C P
Sbjct: 1146 NPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVAAYHCTCEP 1204
Query: 504 GLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDI-------DECR 556
G G CEV+ + C S C N A C NG+ C+C F+G C + +E
Sbjct: 1205 GYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTVCGNEKT 1264
Query: 557 SSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCP 616
+ C NGG C + C C PGF G C+ ++DEC SDPC G C DL F CLC
Sbjct: 1265 NLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCD 1324
Query: 617 SGFTGQLCEVPL 628
F G+ CEV L
Sbjct: 1325 VAFAGERCEVDL 1336
Score = 159 bits (401), Expect = 3e-38
Identities = 80/215 (37%), Positives = 109/215 (50%), Gaps = 16/215 (7%)
Query: 390 CHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHG 449
C ++C S PC C + S C C G+SG C ++DEC +PC HG
Sbjct: 1137 CLQLNVCNSNPCLHGGNCED--IYSSYHCSCPLGWSGKHCELNIDECFS-----NPCIHG 1189
Query: 450 GSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQL 509
+C + +++C C PGYTG CE D + C S C G+TC+ + CLC G+
Sbjct: 1190 -NCSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKF 1248
Query: 510 CE-------VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCAN 562
C V NE + C N +C + +C+C PGF+G CE+DIDEC S PC N
Sbjct: 1249 CRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVN 1308
Query: 563 GGQCQDQPGAFHCKCLPGFEGPRCQTEV-DECLSD 596
GG CQD F C C F G RC+ ++ D+ +SD
Sbjct: 1309 GGLCQDLLNKFQCLCDVAFAGERCEVDLADDLISD 1343
Score = 156 bits (395), Expect = 2e-37
Identities = 73/219 (33%), Positives = 108/219 (49%), Gaps = 20/219 (9%)
Query: 512 VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPG 571
++ N C S PCL+ +C D+ + + C C G+SG CE +IDEC S+PC +G C D+
Sbjct: 1138 LQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVA 1196
Query: 572 AFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAP 631
A+HC C PG+ G C+ ++D C S C GA+C+ + CLC FTG+ C
Sbjct: 1197 AYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
Query: 632 NLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAE 691
+C +K N C +G NCT + C+C G+TG CE +
Sbjct: 1257 TVC--------GNEKTNLTCYNGG--------NCTEFQTELK---CMCRPGFTGEWCEKD 1297
Query: 692 LGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEM 730
+ C S PC +GG C + + C C + G C ++
Sbjct: 1298 IDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDL 1336
Score = 151 bits (382), Expect = 5e-36
Identities = 71/200 (35%), Positives = 97/200 (48%), Gaps = 7/200 (3%)
Query: 691 ELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGG 750
+L C S PC HGG C S Y+C+CP G++G C + C S PC++G +C+
Sbjct: 1139 QLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHG-NCSDRVAA 1197
Query: 751 YYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPS- 809
Y+CTC P +TG C+ D C S C NG TC++ +SCLC F G C PS
Sbjct: 1198 YHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPST 1257
Query: 810 -CADS----PCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGP 864
C + C N C + +C+C G+TG C+ +D CA PC C
Sbjct: 1258 VCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLN 1317
Query: 865 SFHCLCLQGWTGPLCNLPLS 884
F CLC + G C + L+
Sbjct: 1318 KFQCLCDVAFAGERCEVDLA 1337
Score = 148 bits (373), Expect = 6e-35
Identities = 69/204 (33%), Positives = 102/204 (50%), Gaps = 19/204 (9%)
Query: 280 CVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSF 339
C S+ C +GG C+D +Y C CP W+G C ++DEC + H G C + ++
Sbjct: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIH----GNCSDRVAAY 1198
Query: 340 HCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHL----EDM 395
HC C G+ G +CE ++D+C + CA G+TCI +SCLC TG C +
Sbjct: 1199 HCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTV 1258
Query: 396 CLSQ----PCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGS 451
C ++ C+ C+ C+C+PG++G C +D+DEC PC +GG
Sbjct: 1259 CGNEKTNLTCYNGGNCT--EFQTELKCMCRPGFTGEWCEKDIDEC-----ASDPCVNGGL 1311
Query: 452 CLNTPGSFNCLCPPGYTGSRCEAD 475
C + F CLC + G RCE D
Sbjct: 1312 CQDLLNKFQCLCDVAFAGERCEVD 1335
Score = 142 bits (357), Expect = 4e-33
Identities = 71/210 (33%), Positives = 99/210 (47%), Gaps = 20/210 (9%)
Query: 845 MDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNG 904
+++C PC +C S+HC C GW+G C L + C S+ C +G
Sbjct: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDEC----------FSNPCIHG 1189
Query: 905 GLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQN 964
C D +Y C C PG+ G C+ ++ C+S C NGATC++ +GY C C + G+
Sbjct: 1190 N-CSDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKF 1248
Query: 965 CSKE---LDACQSQ----PCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHP 1017
C + C ++ C+N G CT C C PGF G CE D+DEC PC
Sbjct: 1249 CRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVN 1308
Query: 1018 TGTAACHSLANAFYCQCLPGHTGQWCEVEI 1047
G C L N F C C G+ CEV++
Sbjct: 1309 GG--LCQDLLNKFQCLCDVAFAGERCEVDL 1336
Score = 139 bits (349), Expect = 4e-32
Identities = 69/203 (33%), Positives = 97/203 (47%), Gaps = 11/203 (5%)
Query: 195 VNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPE 254
+N C + PC G +C + S+ C CP+G G CEL C C +G +
Sbjct: 1140 LNVC--NSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCIHGNCS----D 1193
Query: 255 KDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSED 314
+ + +H C C PG+ G +CEV+ DNC SHQC NG TC + Y+CLC +TG C +
Sbjct: 1194 RVAAYH-CTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFGNFTGKFCRQS 1252
Query: 315 VDECETQGPPH----CRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTC 370
G C NGG C C+C G+ G CE+++D+C + C G C
Sbjct: 1253 RLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLC 1312
Query: 371 IDRVGSFSCLCPPGRTGLLCHLE 393
D + F CLC G C ++
Sbjct: 1313 QDLLNKFQCLCDVAFAGERCEVD 1335
Score = 136 bits (343), Expect = 2e-31
Identities = 70/212 (33%), Positives = 102/212 (48%), Gaps = 17/212 (8%)
Query: 154 CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHN 213
C + C++NPC++GG C Y C CP G+ G CE +++ECF + PC G +C +
Sbjct: 1137 CLQLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSN--PCIHG-NCSD 1193
Query: 214 TLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDC 273
+ ++ C C G G CE+ C C+NG TC + + CLC F G C
Sbjct: 1194 RVAAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATC----ISHTNGYSCLCFGNFTGKFC 1249
Query: 274 EVN--PDNCVSHQ-----CQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHC 326
+ P ++ C NGG C + C+C +TG C +D+DEC + C
Sbjct: 1250 RQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASD---PC 1306
Query: 327 RNGGTCQNSAGSFHCVCVSGWGGTSCEENLDD 358
NGG CQ+ F C+C + G CE +L D
Sbjct: 1307 VNGGLCQDLLNKFQCLCDVAFAGERCEVDLAD 1338
Score = 134 bits (338), Expect = 7e-31
Identities = 93/340 (27%), Positives = 131/340 (38%), Gaps = 28/340 (8%)
Query: 923 QGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDG--QNCSKELDACQSQPCHNH 980
+ S C + C S CQN +TC C C+ + ++C D C S PC
Sbjct: 23 KNSFCNKNNTRCLSNSCQNNSTCKDFSKDNDCSCSDTANNLDKDCDNMKDPCFSNPCQGS 82
Query: 981 GTCTPKPG--GFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGH 1038
TC PG F C CPPG+ G CE + C C G CH C C G+
Sbjct: 83 ATCVNTPGERSFLCKCPPGYSGTICETTIGSCGKNSCQHGG--ICHQDPIYPVCICPAGY 140
Query: 1039 TGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHH 1098
G++CE++ D C S PC +G C+ G+ C C G++G C C C +
Sbjct: 141 AGRFCEIDHDECASSPCQNGAVCQDGID---GYSCFCVPGYQGRHCDLEVDECASDPCKN 197
Query: 1099 GGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFR 1158
CL C C Y G +C C PCL +C + G +
Sbjct: 198 EATCLNEIG---RYTCICPHNYSGVNC--ELEIDECW-SQPCLNGATCQDALG----AYF 247
Query: 1159 CSCPHSSPGPRCQ----KPGAKGC--EGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPW- 1211
C C G C+ + ++ C G DG C+ G + G C +P W
Sbjct: 248 CDCAPGFLGDHCELNTDECASQPCLHGGLCVDGENRYSCNCTGSGFTGTHCETLMPLCWS 307
Query: 1212 KGCPSHSRCWLLFRDGQCH--PQCDSEECLFDGYDCETPP 1249
K C +++ C + CH P +C D +C + P
Sbjct: 308 KPCHNNATCEDSVDNYTCHCWPGYTGAQCEIDLNECNSNP 347
Score = 133 bits (335), Expect = 2e-30
Identities = 66/209 (31%), Positives = 91/209 (43%), Gaps = 18/209 (8%)
Query: 810 CADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCL 869
C +PC + C+D C CP G++G C+ +D C PC + +C ++HC
Sbjct: 1143 CNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCI-HGNCSDRVAAYHCT 1201
Query: 870 CLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQD 929
C G+TG C + + +CQ S C NG C+ Y C C F G C+
Sbjct: 1202 CEPGYTGVNCEVDIDNCQ----------SHQCANGATCISHTNGYSCLCFGNFTGKFCRQ 1251
Query: 930 HVNPCE-------SRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGT 982
P + C NG C + C C PG+ G+ C K++D C S PC N G
Sbjct: 1252 SRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGL 1311
Query: 983 CTPKPGGFHCACPPGFVGLRCEGDVDECL 1011
C F C C F G RCE D+ + L
Sbjct: 1312 CQDLLNKFQCLCDVAFAGERCEVDLADDL 1340
Score = 131 bits (330), Expect = 6e-30
Identities = 88/272 (32%), Positives = 113/272 (41%), Gaps = 49/272 (18%)
Query: 33 EPCANGGTCLSLSLGQGTCQCAPGFLGETCQF-PDPCQNAQLCQNGGSCQALLPAPLGLP 91
+PC NG TC +LG C CAPGFLG+ C+ D C +Q C +GG C
Sbjct: 231 QPCLNGATCQD-ALGAYFCDCAPGFLGDHCELNTDECA-SQPCLHGGLC----------- 277
Query: 92 SSPSPLTPSFLCTCL-PGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWT 150
+ C C GFTG C+ L C C C + C C PG+T
Sbjct: 278 ---VDGENRYSCNCTGSGFTGTHCET-LMPLCWSKPCHNNATCE-DSVDNYTCHCWPGYT 332
Query: 151 GEQCQL-RDFCSANPCVNGGVCLATYPQIQ--------------------CHCPPGFEGH 189
G QC++ + C++NPC + G C+ + Q C C PGF G
Sbjct: 333 GAQCEIDLNECNSNPCQSNGECVELSSEKQYGRITGLPSSFSYHEASGYVCICQPGFTGI 392
Query: 190 ACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQ------EGPRCELRAGPCPPRGC 243
CE DVNEC PC G +C N G++ C CP G C C + C
Sbjct: 393 HCEEDVNEC--SSNPCQNGGTCENLPGNYTCHCPFDNLSRTFYGGRDCSDILLGCTHQQC 450
Query: 244 SNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEV 275
N GTC + CLCP G+ G CE+
Sbjct: 451 LNNGTCIPHFQDGQHGFSCLCPSGYTGSLCEI 482
Score = 124 bits (310), Expect = 1e-27
Identities = 65/202 (32%), Positives = 87/202 (43%), Gaps = 16/202 (7%)
Query: 931 VNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGF 990
+N C S PC +G C S Y C C G+ G++C +D C S PC HG C+ + +
Sbjct: 1140 LNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPC-IHGNCSDRVAAY 1198
Query: 991 HCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDP- 1049
HC C PG+ G+ CE D+D C C A C S N + C C TG++C P
Sbjct: 1199 HCTCEPGYTGVNCEVDIDNCQSHQC--ANGATCISHTNGYSCLCFGNFTGKFCRQSRLPS 1256
Query: 1050 --CHSQ----PCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCL 1103
C ++ C++GG C C C GF G C C C +GGLC
Sbjct: 1257 TVCGNEKTNLTCYNGGNCTEFQTE---LKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQ 1313
Query: 1104 PSPKPGFPPRCACLSGYGGPDC 1125
+C C + G C
Sbjct: 1314 DLLNKF---QCLCDVAFAGERC 1332
Score = 122 bits (306), Expect = 4e-27
Identities = 70/202 (34%), Positives = 90/202 (44%), Gaps = 16/202 (7%)
Query: 122 CPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR-DFCSANPCVNGGVCLATYPQIQC 180
C + C G C S CSC GW+G+ C+L D C +NPC++G C C
Sbjct: 1143 CNSNPCLHGGNCEDIYSSY-HCSCPLGWSGKHCELNIDECFSNPCIHGN-CSDRVAAYHC 1200
Query: 181 HCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPP 240
C PG+ G CE D++ C C G +C + + CLC G C P
Sbjct: 1201 TCEPGYTGVNCEVDIDNC--QSHQCANGATCISHTNGYSCLCFGNFTGKFCRQSRLPSTV 1258
Query: 241 RG-------CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQD 293
G C NGG C + T C+C PGF G CE + D C S C NGG CQD
Sbjct: 1259 CGNEKTNLTCYNGGNCT----EFQTELKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQD 1314
Query: 294 GLDTYTCLCPETWTGWDCSEDV 315
L+ + CLC + G C D+
Sbjct: 1315 LLNKFQCLCDVAFAGERCEVDL 1336
Score = 115 bits (287), Expect = 6e-25
Identities = 70/211 (33%), Positives = 94/211 (44%), Gaps = 23/211 (10%)
Query: 968 ELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLA 1027
+L+ C S PC + G C +HC+CP G+ G CE ++DEC PC C
Sbjct: 1139 QLNVCNSNPCLHGGNCEDIYSSYHCSCPLGWSGKHCELNIDECFSNPCI---HGNCSDRV 1195
Query: 1028 NAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTC-SH 1086
A++C C PG+TG CEV+ID C S C +G TC + G+ C C F G C
Sbjct: 1196 AAYHCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTN---GYSCLCFGNFTGKFCRQS 1252
Query: 1087 RAPS--CGFHH----CHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPC 1140
R PS CG C++GG C +C C G+ G C C PC
Sbjct: 1253 RLPSTVCGNEKTNLTCYNGGNCTEFQT---ELKCMCRPGFTGEWC--EKDIDECA-SDPC 1306
Query: 1141 LYNGSCSETTGLGGPGFRCSCPHSSPGPRCQ 1171
+ G C + F+C C + G RC+
Sbjct: 1307 VNGGLCQDLLN----KFQCLCDVAFAGERCE 1333
Score = 92.8 bits (229), Expect = 3e-18
Identities = 56/214 (26%), Positives = 87/214 (40%), Gaps = 73/214 (34%)
Query: 70 NAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLED----PCPPS 125
N+ C +GG+C+ + S+ C+C G++G+ C+ +++ PC
Sbjct: 1144 NSNPCLHGGNCEDIYS--------------SYHCSCPLGWSGKHCELNIDECFSNPCIHG 1189
Query: 126 FCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR-DFCSANPCVNGGVCLA----------- 173
CS R + C+C PG+TG C++ D C ++ C NG C++
Sbjct: 1190 NCSDRVAAY-------HCTCEPGYTGVNCEVDIDNCQSHQCANGATCISHTNGYSCLCFG 1242
Query: 174 ----------------------------------TYPQIQCHCPPGFEGHACERDVNECF 199
+++C C PGF G CE+D++EC
Sbjct: 1243 NFTGKFCRQSRLPSTVCGNEKTNLTCYNGGNCTEFQTELKCMCRPGFTGEWCEKDIDECA 1302
Query: 200 QDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCEL 233
D PC G C + L FQCLC V G RCE+
Sbjct: 1303 SD--PCVNGGLCQDLLNKFQCLCDVAFAGERCEV 1334
Score = 85.9 bits (211), Expect = 4e-16
Identities = 55/176 (31%), Positives = 77/176 (43%), Gaps = 32/176 (18%)
Query: 31 FPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLG 89
F PC +G S + C C PG+ G C+ D CQ+ Q C NG +C +
Sbjct: 1182 FSNPCIHGNC--SDRVAAYHCTCEPGYTGVNCEVDIDNCQSHQ-CANGATCIS------- 1231
Query: 90 LPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKR---------GRCHIQASGR 140
T + C C FTG+ C+ + P + C G C +
Sbjct: 1232 -------HTNGYSCLCFGNFTGKFCR---QSRLPSTVCGNEKTNLTCYNGGNC-TEFQTE 1280
Query: 141 PQCSCMPGWTGEQCQLR-DFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDV 195
+C C PG+TGE C+ D C+++PCVNGG+C + QC C F G CE D+
Sbjct: 1281 LKCMCRPGFTGEWCEKDIDECASDPCVNGGLCQDLLNKFQCLCDVAFAGERCEVDL 1336
Score = 61.6 bits (148), Expect = 7e-09
Identities = 29/72 (40%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
Query: 474 ADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLN 533
A N C S PCH G C F C CP G+ CE E C +PC + A C +L
Sbjct: 886 AGDNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQ 944
Query: 534 GFQCICLPGFSG 545
GF+CI F+G
Sbjct: 945 GFECIANAVFNG 956
Score = 57.8 bits (138), Expect = 1e-07
Identities = 30/78 (38%), Positives = 37/78 (47%), Gaps = 6/78 (7%)
Query: 154 CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHN 213
C + C +NPC NGGVC + + C CP G ACE +V C PCP G C
Sbjct: 885 CAGDNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWC--GFSPCPHGAQCQP 941
Query: 214 TLGSFQCLCPV---GQEG 228
L F+C+ GQ G
Sbjct: 942 VLQGFECIANAVFNGQSG 959
Score = 56.2 bits (134), Expect = 3e-07
Identities = 27/70 (38%), Positives = 35/70 (50%), Gaps = 1/70 (1%)
Query: 553 DECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFF 612
+ C+S+PC NGG C + F C C G C+ EV C PCP GA C + F
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 613 CLCPSGFTGQ 622
C+ + F GQ
Sbjct: 948 CIANAVFNGQ 957
Score = 54.3 bits (129), Expect = 1e-06
Identities = 28/69 (40%), Positives = 31/69 (44%), Gaps = 1/69 (1%)
Query: 515 NECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFH 574
N C S PC N CH + F C C SG CEE + C SPC +G QCQ F
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQPVLQGFE 947
Query: 575 CKCLPGFEG 583
C F G
Sbjct: 948 CIANAVFNG 956
Score = 53.5 bits (127), Expect = 2e-06
Identities = 33/87 (37%), Positives = 37/87 (42%), Gaps = 17/87 (19%)
Query: 35 CANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPSS 93
C NGG C + C C PGF GE C+ D C + C NGG CQ LL
Sbjct: 1268 CYNGGNCTEFQT-ELKCMCRPGFTGEWCEKDIDECASDP-CVNGGLCQDLLN-------- 1317
Query: 94 PSPLTPSFLCTCLPGFTGERCQAKLED 120
F C C F GERC+ L D
Sbjct: 1318 ------KFQCLCDVAFAGERCEVDLAD 1338
Score = 53.1 bits (126), Expect = 3e-06
Identities = 30/74 (40%), Positives = 34/74 (45%), Gaps = 2/74 (2%)
Query: 771 CVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC 830
C S PC NGG C +R FSC C G CE C SPC + A CQ QG C
Sbjct: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEV--QWCGFSPCPHGAQCQPVLQGFEC 948
Query: 831 LCPTGYTGGSCQTL 844
+ + G S Q L
Sbjct: 949 IANAVFNGQSGQIL 962
Score = 53.1 bits (126), Expect = 3e-06
Identities = 36/128 (28%), Positives = 50/128 (39%), Gaps = 14/128 (10%)
Query: 1045 VEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLP 1104
++++ C+S PC HGG CE S + C CP G+ G C C + C HG C
Sbjct: 1138 LQLNVCNSNPCLHGGNCEDIYSS---YHCSCPLGWSGKHCELNIDECFSNPCIHGN-CSD 1193
Query: 1105 SPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHS 1164
C C GY G +C C C +C T G+ C C +
Sbjct: 1194 RVA---AYHCTCEPGYTGVNCEVD--IDNC-QSHQCANGATCISHTN----GYSCLCFGN 1243
Query: 1165 SPGPRCQK 1172
G C++
Sbjct: 1244 FTGKFCRQ 1251
Score = 52.8 bits (125), Expect = 3e-06
Identities = 22/59 (37%), Positives = 32/59 (54%), Gaps = 1/59 (1%)
Query: 695 CISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYC 753
C S PC +GG C+ + ++C+CP +G C EE+ C PC +G C P G+ C
Sbjct: 891 CKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSPCPHGAQCQPVLQGFEC 948
Score = 50.1 bits (118), Expect = 2e-05
Identities = 23/67 (34%), Positives = 33/67 (49%), Gaps = 1/67 (1%)
Query: 898 SSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCA 957
S+ CHNGG+C + C CP G C++ V C PC +GA C G+ C
Sbjct: 893 SNPCHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQPVLQGFECIAN 951
Query: 958 PGYDGQN 964
++GQ+
Sbjct: 952 AVFNGQS 958
Score = 49.7 bits (117), Expect = 3e-05
Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 4/74 (5%)
Query: 278 DNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAG 337
++C S+ C NGG C D ++C CP +G C E+V C G C +G CQ
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWC---GFSPCPHGAQCQPVLQ 944
Query: 338 SFHCVCVSGWGGTS 351
F C+ + + G S
Sbjct: 945 GFECIANAVFNGQS 958
Score = 49.3 bits (116), Expect = 4e-05
Identities = 23/69 (33%), Positives = 31/69 (44%), Gaps = 1/69 (1%)
Query: 932 NPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFH 991
N C+S PC NG C ++ + C C G+ C +E+ C PC + C P GF
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKAC-EEVQWCGFSPCPHGAQCQPVLQGFE 947
Query: 992 CACPPGFVG 1000
C F G
Sbjct: 948 CIANAVFNG 956
Score = 48.5 bits (114), Expect = 6e-05
Identities = 27/70 (38%), Positives = 36/70 (51%), Gaps = 4/70 (5%)
Query: 963 QNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAA 1022
Q C+ + ++C+S PCHN G C + F C+CP G CE +V C PC P G A
Sbjct: 883 QGCAGD-NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPC-PHG-AQ 938
Query: 1023 CHSLANAFYC 1032
C + F C
Sbjct: 939 CQPVLQGFEC 948
Score = 48.1 bits (113), Expect = 8e-05
Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 1/68 (1%)
Query: 732 ACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSC 791
+C S PC NGG C+ + C+CP +G C+ +C +PC +G C F C
Sbjct: 890 SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFEC 948
Query: 792 LCAMGFQG 799
+ F G
Sbjct: 949 IANAVFNG 956
Score = 47.4 bits (111), Expect = 1e-04
Identities = 29/79 (36%), Positives = 35/79 (44%), Gaps = 7/79 (8%)
Query: 1003 CEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCE 1062
C GD + C PCH G CHS + F C C +G+ CE E+ C PC HG C+
Sbjct: 885 CAGD-NSCKSNPCHNGGV--CHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQ 940
Query: 1063 ATAGSPLGFICHCPKGFEG 1081
GF C F G
Sbjct: 941 PVL---QGFECIANAVFNG 956
Score = 45.8 bits (107), Expect = 4e-04
Identities = 22/65 (33%), Positives = 31/65 (47%), Gaps = 1/65 (1%)
Query: 444 SPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPP 503
+PC +GG C + F+C CP +G CE + C PC G+ C +L F C+
Sbjct: 894 NPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQPVLQGFECIANA 952
Query: 504 GLEGQ 508
GQ
Sbjct: 953 VFNGQ 957
Score = 43.5 bits (101), Expect = 0.002
Identities = 21/55 (38%), Positives = 23/55 (41%), Gaps = 4/55 (7%)
Query: 1050 CHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLP 1104
C S PC +GG C + F C CP G C CGF C HG C P
Sbjct: 891 CKSNPCHNGGVCHSRWDD---FSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQP 941
Score = 42.7 bits (99), Expect = 0.004
Identities = 18/61 (29%), Positives = 25/61 (40%), Gaps = 1/61 (1%)
Query: 809 SCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHC 868
SC +PC N C C CP +G +C+ + C PCP + C F C
Sbjct: 890 SCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQPVLQGFEC 948
Query: 869 L 869
+
Sbjct: 949 I 949
Score = 40.8 bits (94), Expect = 0.013
Identities = 25/75 (33%), Positives = 34/75 (45%), Gaps = 10/75 (13%)
Query: 657 GCAPPEDNCT---CHHGHCQRS-----SCVCDVGWTGPECEAELGGCISAPCAHGGTCYP 708
GCA +++C CH+G S SC C +G CE E+ C +PC HG C P
Sbjct: 884 GCAG-DNSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQP 941
Query: 709 QPSGYNCTCPTGYTG 723
G+ C + G
Sbjct: 942 VLQGFECIANAVFNG 956
Score = 40.8 bits (94), Expect = 0.013
Identities = 24/79 (30%), Positives = 30/79 (37%), Gaps = 9/79 (11%)
Query: 348 GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQC 407
G SC+ N C G C R FSC CP +G C C PC AQC
Sbjct: 887 GDNSCKSN-------PCHNGGVCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQC 939
Query: 408 STNPLTGSTLCLCQPGYSG 426
P+ C+ ++G
Sbjct: 940 --QPVLQGFECIANAVFNG 956
Score = 39.3 bits (90), Expect = 0.039
Identities = 23/80 (28%), Positives = 31/80 (38%), Gaps = 8/80 (10%)
Query: 390 CHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHG 449
C ++ C S PCH C + C C SG C +++ C G SPC HG
Sbjct: 885 CAGDNSCKSNPCHNGGVCHSR--WDDFSCSCPALTSGKAC-EEVQWC-----GFSPCPHG 936
Query: 450 GSCLNTPGSFNCLCPPGYTG 469
C F C+ + G
Sbjct: 937 AQCQPVLQGFECIANAVFNG 956
Score = 38.9 bits (89), Expect = 0.051
Identities = 15/35 (42%), Positives = 20/35 (57%)
Query: 934 CESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKE 968
CES+PCQ+ C+ Y C C Y+G NC +E
Sbjct: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLRE 710
Score = 38.9 bits (89), Expect = 0.051
Identities = 18/55 (32%), Positives = 26/55 (47%), Gaps = 1/55 (1%)
Query: 326 CRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCL 380
C NGG C + F C C + G +CEE + C + C G+ C + F C+
Sbjct: 896 CHNGGVCHSRWDDFSCSCPALTSGKACEE-VQWCGFSPCPHGAQCQPVLQGFECI 949
Score = 37.7 bits (86), Expect = 0.11
Identities = 35/122 (28%), Positives = 44/122 (36%), Gaps = 9/122 (7%)
Query: 80 CQALLPAPLGLPSSPSPLTPSFLCTCLPGFT--GERCQAKLEDPCPPSFCS-----KRGR 132
C A P PL S SFL G T G P PSF K
Sbjct: 591 CIAKAPTPLESDQSICAFQNSFLGGLPVGMTSNGVALLNFYNMPSTPSFVGCLQDIKIDW 650
Query: 133 CHIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACE 192
HI S + G C +D+C + PC + G C+ + QC C +EG C
Sbjct: 651 NHITLENISSGSSLNVKAG--CVRKDWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCL 708
Query: 193 RD 194
R+
Sbjct: 709 RE 710
Score = 36.6 bits (83), Expect = 0.25
Identities = 13/34 (38%), Positives = 20/34 (58%)
Query: 769 DYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRC 802
D+C S PC + G C+N ++ C C ++GP C
Sbjct: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNC 707
Score = 36.2 bits (82), Expect = 0.33
Identities = 18/72 (25%), Positives = 30/72 (41%), Gaps = 1/72 (1%)
Query: 119 EDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQI 178
++ C + C G CH + CSC +G+ C+ +C +PC +G C
Sbjct: 888 DNSCKSNPCHNGGVCHSRWDDF-SCSCPALTSGKACEEVQWCGFSPCPHGAQCQPVLQGF 946
Query: 179 QCHCPPGFEGHA 190
+C F G +
Sbjct: 947 ECIANAVFNGQS 958
Score = 36.2 bits (82), Expect = 0.33
Identities = 17/47 (36%), Positives = 19/47 (40%), Gaps = 1/47 (2%)
Query: 204 PCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQ 250
PC G CH+ F C CP G CE C C +G CQ
Sbjct: 895 PCHNGGVCHSRWDDFSCSCPALTSGKACE-EVQWCGFSPCPHGAQCQ 940
Score = 35.4 bits (80), Expect = 0.57
Identities = 14/37 (37%), Positives = 20/37 (54%)
Query: 553 DECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTE 589
D C S PC + G+C + ++ C C +EGP C E
Sbjct: 674 DWCESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLRE 710
Score = 34.7 bits (78), Expect = 0.96
Identities = 16/42 (38%), Positives = 16/42 (38%)
Query: 695 CISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSG 736
C S PC G C Y C C Y GP C E A G
Sbjct: 676 CESQPCQSRGRCINLWLSYQCDCHRPYEGPNCLREYVAGRFG 717
Score = 32.7 bits (73), Expect = 3.7
Identities = 16/40 (40%), Positives = 19/40 (47%), Gaps = 3/40 (7%)
Query: 1045 VEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTC 1084
V D C SQPC G C L + C C + +EGP C
Sbjct: 671 VRKDWCESQPCQSRGRC---INLWLSYQCDCHRPYEGPNC 707
Score = 32.3 bits (72), Expect = 4.8
Identities = 18/61 (29%), Positives = 26/61 (42%), Gaps = 1/61 (1%)
Query: 591 DECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLC-EVPLCAPNLCQPKQICKDQKDKANC 649
+ C S+PC G C F C CP+ +G+ C EV C + C C+ C
Sbjct: 889 NSCKSNPCHNGGVCHSRWDDFSCSCPALTSGKACEEVQWCGFSPCPHGAQCQPVLQGFEC 948
Query: 650 L 650
+
Sbjct: 949 I 949
Score = 32.0 bits (71), Expect = 6.2
Identities = 16/40 (40%), Positives = 18/40 (45%), Gaps = 2/40 (5%)
Query: 390 CHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTC 429
C +D C SQPC +C L S C C Y GP C
Sbjct: 670 CVRKDWCESQPCQSRGRCIN--LWLSYQCDCHRPYEGPNC 707
>gi|56237021 fibrillin 3 precursor [Homo sapiens]
Length = 2809
Score = 353 bits (906), Expect = 9e-97
Identities = 394/1354 (29%), Positives = 519/1354 (38%), Gaps = 280/1354 (20%)
Query: 33 EPCANGGTCLSLSL----GQGTCQCAPGFL----GETCQFPDPCQNAQLCQNG------G 78
+ CA G C S G C C G+ G C + C + C NG G
Sbjct: 1406 DECAQGNLCAFGSCENLPGMFRCICNGGYELDRGGGNCTDINECADPVNCINGVCINTPG 1465
Query: 79 SCQALLPA-----PLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE-DPCPPSFCSKRGR 132
S P P G+ + FL T G +G C A++ S C GR
Sbjct: 1466 SYLCSCPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGR 1525
Query: 133 -----CHI--QASGRPQCSCMPGWTGEQ-------CQLRDFCSANPCV-NGGVCLATYPQ 177
C + A+ + PG G Q + D C P + GG C+ T+
Sbjct: 1526 AWGNPCELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGS 1585
Query: 178 IQCHCPPGFE----GHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG----QEGP 229
QC CPPG+ CE D++EC G C GT C+NTLG++ C+CP G
Sbjct: 1586 FQCECPPGYHLSEHTRICE-DIDECSTHSGICGPGT-CYNTLGNYTCVCPAEYLQVNGGN 1643
Query: 230 RC-ELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNG 288
C ++R C GTCQ + T +C C N + C+
Sbjct: 1644 NCMDMRKSVCFRH---YNGTCQNELAFNVTRKMCCC---------SYNIGQAWNRPCE-- 1689
Query: 289 GTCQDGLDT-YTCLCPETWTGWDCSE------DVDECETQGPPHCRNGGTCQNSAGSFHC 341
C + Y LC G+ D+DEC + P C NG C N GSF C
Sbjct: 1690 -ACPTPISPDYQILCGNQAPGFLTDIHTGKPLDIDECG-EIPAICANG-ICINQIGSFRC 1746
Query: 342 VCVSGWGGTS----CEENLDDCIA--ATCAPGSTCIDRVGSFSCLCPPG---RTGLLCHL 392
C +G+ S CE+ +D+C + + C + CI+ GS+ C C G G C
Sbjct: 1747 ECPAGFNYNSILLACED-VDECGSRESPCQQNADCINIPGSYRCKCTRGYKLSPGGACVG 1805
Query: 393 EDMCLSQP---CHGDAQCSTNPLTGSTLCLCQPGYSGP---TCHQDLDECLMAQQGPSPC 446
+ C P HGD + GS +CLC G+ T D+DEC PC
Sbjct: 1806 RNECREIPNVCSHGDCMDTE----GSYMCLCHRGFQASADQTLCMDIDEC-----DRQPC 1856
Query: 447 EHGGSCLNTPGSFNCLCPPGY--TGSRCEADHNEC---LSQPCHPGSTCLDLLATFHCLC 501
+G +C N GS+NCLC PG+ T + D +EC + Q C G CL+ +FHCLC
Sbjct: 1857 GNG-TCKNIIGSYNCLCFPGFVVTHNGDCVDFDECTTLVGQVCRFGH-CLNTAGSFHCLC 1914
Query: 502 PPGLE----GQLCEVETNECAS--APCLNHADCHDLLNGFQCICLPGFS--GTRCEEDID 553
G E G+ C V+TNEC S CL C +L F+CIC PGF C DID
Sbjct: 1915 QDGFELTADGKNC-VDTNECLSLAGTCLP-GTCQNLEGSFRCICPPGFQVQSDHCI-DID 1971
Query: 554 ECRSSP-CANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFF 612
EC P G C + PG+F C C PGF LSD G C D +F
Sbjct: 1972 ECSEEPNLCLFGTCTNSPGSFQCLCPPGF-----------VLSDN---GHRCFDTRQSF- 2016
Query: 613 CLCPSGFTGQLCEVPLC----APNLC----------QPKQICKDQKDKA-NCLCPDGSPG 657
C + F C VP C P ++C + A LCP G
Sbjct: 2017 --CFTRFEAGKCSVPKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGA 2074
Query: 658 CAPPEDN------CTCHHGHCQRSSCV---------CDVGW----TGPECEAELGGCISA 698
P+D+ C + G C CV C G+ TG C +
Sbjct: 2075 VPGPDDSREDVNECAENPGVCTNGVCVNTDGSFRCECPFGYSLDFTGINCVDTDECSVGH 2134
Query: 699 PCAHGGTCYPQPSGYNCTCPTGYTGP---TCSEEMTACHSGPCLNGGSCNPSPGGYYCTC 755
PC G TC G+ C C G+ TC E++ C P L C+ + G Y CTC
Sbjct: 2135 PCGQG-TCTNVIGGFECACADGFEPGLMMTC-EDIDECSLNPLLCAFRCHNTEGSYLCTC 2192
Query: 756 PPSHT----GPQCQTSTDYCVSAP--CF-NGGTCVNRPGTFSCLCAMGFQ-----GPRCE 803
P +T G C+ D C C G C N GTF+C+C G + G C
Sbjct: 2193 PAGYTLREDGAMCR-DVDECADGQQDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGCT 2251
Query: 804 GKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPC---PRNSHCL 860
C N C ++ RC C G+ T Q PC + C
Sbjct: 2252 DDNECHAQPDLCVN-GRCVNTAGSFRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCR 2310
Query: 861 QTGPSFH------CLCL--QGWTGP---LCNLPLSSCQKAAL-------SQGIDVSS--- 899
S C C +GW GP LC LP +S + ++G DV
Sbjct: 2311 SLSSSSEAVTRAECCCGGGRGW-GPRCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRM 2369
Query: 900 ---LCHNGGLCVDSGPSYFCHCPPGFQ----GSLCQDHVNPCESRPCQNGATCMAQPSGY 952
LC +G C++S S+ CHC G+ + C D ++ C P C +
Sbjct: 2370 LAHLCAHGE-CINSLGSFRCHCQAGYTPDATATTCLD-MDECSQVPKPCTFLCKNTKGSF 2427
Query: 953 LCQCAPGY----DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFV-GLRCEGDV 1007
LC C GY DG+ C K+LD C S+ + C G F C CPPGF + D
Sbjct: 2428 LCSCPRGYLLEEDGRTC-KDLDECTSRQHNCQFLCVNTVGAFTCRCPPGFTQHHQACFDN 2486
Query: 1008 DECLDQPCHPTGTAACHSLANAFYCQCLPGHT----GQWCEVEIDPCHS-QPCFHGGTCE 1062
DEC QP CH+ +F C+C G T G CE +++ C C HG C+
Sbjct: 2487 DECSAQPGPCGAHGHCHNTPGSFRCECHQGFTLVSSGHGCE-DVNECDGPHRCQHG--CQ 2543
Query: 1063 ATAGSPLGFICHCPKGF----------EGPTCSHRAPSCGFHHCHH--GGLCLPSPKPGF 1110
G G+ C CP+GF + C+ P+CG C + GG
Sbjct: 2544 NQLG---GYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGF--------- 2591
Query: 1111 PPRCACLSGYGGPDCL--TPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGP 1168
RC C SG+ L + G PC Y SC+ T G GF C CP
Sbjct: 2592 --RCVCPSGFDFDQALGGCQEVDECAGRRGPCSY--SCANTPG----GFLCGCPQG---- 2639
Query: 1169 RCQKPGAKGCEGRSGDGACDAGCSGPGGNWDGGD 1202
R+G G C +G G D D
Sbjct: 2640 ----------YFRAGQGHCVSGLGFSPGPQDTPD 2663
Score = 350 bits (898), Expect = 8e-96
Identities = 391/1409 (27%), Positives = 522/1409 (37%), Gaps = 350/1409 (24%)
Query: 34 PCANGGTCLSLSLGQGTCQCAPGFLGE------------TCQFPDPCQNAQLCQNGGS-- 79
PC +G C +L+ G TC+C PG + TC ++ G S
Sbjct: 774 PCVSG-VCRNLA-GSYTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLR 831
Query: 80 --CQALLPAPLGLPSSPSPLTPSFLCTCLPGF---TGERCQAKLEDPCPPSFCSKRGRCH 134
C A L A G P + P+ C GF TG C E P C GRC
Sbjct: 832 SECCATLGAAWGSPCERCEIDPA----CARGFARMTGVTCDDVNECESFPGVCPN-GRC- 885
Query: 135 IQASGRPQCSCMPG---------------------WTGEQCQLR-------DFCSANPCV 166
+ +G +C C G W ++C + D C +
Sbjct: 886 VNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGA 945
Query: 167 NGGVCLATYP-----QIQCHCPPGF--------EGHACERDVNECFQDPGPCPKGTSCHN 213
GV P + CP G G +DVNEC PG C GT C N
Sbjct: 946 VWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGT-CRN 1004
Query: 214 TLGSFQCLCPVG-----QEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGF 268
T+GSF C C G QE ++ P C G TC P +F C C PG+
Sbjct: 1005 TVGSFHCACAGGFALDAQERNCTDIDECRISPDLCGQG-TCVNTP---GSFE-CECFPGY 1059
Query: 269 -----IGPDCEVNPDNCVSHQCQ-NGGTCQDGLDTYTCLCPE----TWTGWDCSEDVDEC 318
+ +C ++ D C GGTC + +Y C CP T G C ED+DEC
Sbjct: 1060 ESGFMLMKNC-MDVDECARDPLLCRGGTCTNTDGSYKCQCPPGHELTAKGTAC-EDIDEC 1117
Query: 319 ETQGP--PHCRNGGTCQNSAGSFHCVCVSGWGGTSCEE---NLDDCIAATCAPGSTCIDR 373
PH G C N G+F C C +G+ T + ++++C CI+
Sbjct: 1118 SLSDGLCPH----GQCVNVIGAFQCSCHAGFQSTPDRQGCVDINECRVQNGGCDVHCINT 1173
Query: 374 VGSFSCLCPPGRT----GLLCHLEDMCLSQP----------------------------- 400
GS+ C C G + G C D C P
Sbjct: 1174 EGSYRCSCGQGYSLMPDGRACADVDECEENPRVCDQGHCTNMPGGHRCLCYDGFMATPDM 1233
Query: 401 --CHGDAQCSTNP----------LTGSTLCLCQPGY---SGPTCHQDLDECLMAQQGPSP 445
C +C NP GS +C CQ GY G T D+DEC + G
Sbjct: 1234 RTCVDVDECDLNPHICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDEC---EVGGHN 1290
Query: 446 CEHGGSCLNTPGSFNCLCPPGYTGSRCEA-DHNECLSQP--CHPGSTCLDLLATFHCLCP 502
C+ SCLN PGSF+C C PG+ G E D +EC+SQ C P CL++ ++ C C
Sbjct: 1291 CDSHASCLNIPGSFSCRCLPGWVGDGFECHDLDECVSQEHRCSPRGDCLNVPGSYRCTCR 1350
Query: 503 PGL--EGQLCEVETNECA-SAPCLNHADCHDLLNGFQCICLPGFSGT---RCEEDIDECR 556
G +G CE + +ECA + ++ C + G++C C GF T R +D+DEC
Sbjct: 1351 QGFAGDGFFCE-DRDECAENVDLCDNGQCLNAPGGYRCECEMGFDPTEDHRACQDVDECA 1409
Query: 557 SSPCANGGQCQDQPGAFHCKCLPGFE----GPRCQTEVDECLSDPCPVGASCLDLPGAFF 612
G C++ PG F C C G+E G C T+++EC + C++ PG++
Sbjct: 1410 QGNLCAFGSCENLPGMFRCICNGGYELDRGGGNC-TDINECADPVNCINGVCINTPGSYL 1468
Query: 613 CLCPSGFTGQLCEVPLCAPNLCQPKQI-CKDQKDKANCLCPDGSPGCAPPEDNCTCHHG- 670
C CP F P + C D + NC G +C+ G
Sbjct: 1469 CSCPQDFE-------------LNPSGVGCVDTR-AGNCFLETHDRG--DSGISCSAEIGV 1512
Query: 671 HCQRSSCVCDVG--WTGPECE-----------------------------AELGGCISAP 699
R+SC C +G W P CE ++ C P
Sbjct: 1513 GVTRASCCCSLGRAWGNP-CELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELP 1571
Query: 700 -CAHGGTCYPQPSGYNCTCPTGY---TGPTCSEEMTAC--HSGPCLNGGSCNPSPGGYYC 753
GG C + C CP GY E++ C HSG C G+C + G Y C
Sbjct: 1572 GLCQGGDCVNTFGSFQCECPPGYHLSEHTRICEDIDECSTHSGIC-GPGTCYNTLGNYTC 1630
Query: 754 TCPPS--------------------HTGPQCQTSTDYCVSAP----CFNGGTCVNRP--- 786
CP H CQ + V+ +N G NRP
Sbjct: 1631 VCPAEYLQVNGGNNCMDMRKSVCFRHYNGTCQNELAFNVTRKMCCCSYNIGQAWNRPCEA 1690
Query: 787 ------GTFSCLC---AMGFQGPRCEGKLR--PSCADSP--CRNRATCQDSPQGPRCLCP 833
+ LC A GF GK C + P C N C + RC CP
Sbjct: 1691 CPTPISPDYQILCGNQAPGFLTDIHTGKPLDIDECGEIPAICAN-GICINQIGSFRCECP 1749
Query: 834 TGYTGGS----CQTLMDLCA--QKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQ 887
G+ S C+ +D C + PC +N+ C+ S+ C C +G+ P +C
Sbjct: 1750 AGFNYNSILLACED-VDECGSRESPCQQNADCINIPGSYRCKCTRGYK----LSPGGAC- 1803
Query: 888 KAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGS----LCQDHVNPCESRPCQNGA 943
++ ++ ++C +G C+D+ SY C C GFQ S LC D ++ C+ +PC NG
Sbjct: 1804 -VGRNECREIPNVCSHGD-CMDTEGSYMCLCHRGFQASADQTLCMD-IDECDRQPCGNG- 1859
Query: 944 TCMAQPSGYLCQCAPGY---DGQNCSKELDACQS---QPCHNHGTCTPKPGGFHCACPPG 997
TC Y C C PG+ +C + D C + Q C G C G FHC C G
Sbjct: 1860 TCKNIIGSYNCLCFPGFVVTHNGDC-VDFDECTTLVGQVC-RFGHCLNTAGSFHCLCQDG 1917
Query: 998 FV----GLRCEGDVDECLD--QPCHPTGTAACHSLANAFYCQCLPGHTGQ--WCEVEIDP 1049
F G C D +ECL C P C +L +F C C PG Q C ++ID
Sbjct: 1918 FELTADGKNCV-DTNECLSLAGTCLP---GTCQNLEGSFRCICPPGFQVQSDHC-IDIDE 1972
Query: 1050 CHSQP--CFHGGTCEATAGSPLGFICHCPKGF----EGPTCSHRAPSCGFHHCHHGGLCL 1103
C +P C GTC SP F C CP GF G C S F G +
Sbjct: 1973 CSEEPNLCLF-GTC---TNSPGSFQCLCPPGFVLSDNGHRCFDTRQSFCFTRFEAGKCSV 2028
Query: 1104 PSPKPGFPPRCACL----SGYGGPDCLTP-----------PAPKGCGP------------ 1136
P RC C G+G P L P P G P
Sbjct: 2029 PKAFNTTKTRCCCSKRPGEGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNEC 2088
Query: 1137 ---PSPCLYNGSCSETTGLGGPGFRCSCP 1162
P C NG C T G FRC CP
Sbjct: 2089 AENPGVCT-NGVCVNTDG----SFRCECP 2112
Score = 315 bits (806), Expect = 4e-85
Identities = 425/1599 (26%), Positives = 562/1599 (35%), Gaps = 451/1599 (28%)
Query: 35 CANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSP 94
C NGGTC S C C G+ G C P C C NGG C
Sbjct: 124 CMNGGTCRGAS-----CLCQKGYTGTVCGQPI-CDRG--CHNGGRC-------------- 161
Query: 95 SPLTPSFLCTCLPGFTGERCQAKLED-PC-------------PPSFCSKRGRCHI--QAS 138
+ P+ C C+ GF G +C+ PC C+K C +A
Sbjct: 162 --IGPN-RCACVYGFMGPQCERDYRTGPCFGQVGPEGCQHQLTGLVCTKALCCATVGRAW 218
Query: 139 GRPQCSC-----------MPGWTGEQCQLRDFCSANPCV-NGGVCLATYPQIQCHCPPGF 186
G P C +P CQ D C A P + GG C+ C CP G
Sbjct: 219 GLPCELCPAQPHPCRRGFIPNIHTGACQDVDECQAVPGLCQGGSCVNMVGSFHCRCPVGH 278
Query: 187 E----GHACER-DVNECFQD--PGPCPKGTSCHNTLGSFQCLCPVGQ---EGPRCELRAG 236
ACE CF G C + H T QC C G+ GP EL
Sbjct: 279 RLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRR--QCCCDRGRCWAAGPVPEL--- 333
Query: 237 PCPPRGCSN-----GGTCQLMPEKDSTFHLCLC-------PPGFIGPDCEVNP------- 277
CPPRG + L+P F L PP +GP +NP
Sbjct: 334 -CPPRGSNEFQQLCAQRLPLLPGHPGLFPGLLGFGSNGMGPP--LGP-ARLNPHGSDARG 389
Query: 278 --------------------DNC--VSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSE-- 313
D C ++ C NG C +Y C C +T E
Sbjct: 390 IPSLGPGNSNIGTATLNQTIDICRHFTNLCLNG-RCLPTPSSYRCECNVGYTQDVRGECI 448
Query: 314 DVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEE---NLDDCIAA--TCAPGS 368
DVDEC T P H G C N G++HC C G+ T + ++D+CI + C G
Sbjct: 449 DVDEC-TSSPCH---HGDCVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGGLCHLGR 504
Query: 369 TCIDRVGSFSCLC-------PPGRTGL---LCHLEDMCLSQPCHGDAQCSTNPLTGSTLC 418
C++ GSF C+C P G+ + C MC++ C + GS C
Sbjct: 505 -CVNTEGSFQCVCNAGFELSPDGKNCVDHNECATSTMCVNGVCLNE--------DGSFSC 555
Query: 419 LCQPGY----SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT----GS 470
LC+PG+ G C D+DEC Q P C +G C NT GSF C C G G
Sbjct: 556 LCKPGFLLAPGGHYC-MDIDEC----QTPGICVNG-HCTNTEGSFRCQCLGGLAVGTDGR 609
Query: 471 RCEADHNE-------------------------CLSQPCHPGSTCLDLL-----ATFHCL 500
C H C + P H L A F L
Sbjct: 610 VCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQAL 669
Query: 501 CPPGLEGQLCEVETNECASAP--CLNHADCHDLLNGFQCICLPGF----SGTRCEEDIDE 554
C GL + NECA P C N C +L ++C+C G+ SG C D+DE
Sbjct: 670 CSSGLGITTDGRDINECALDPEVCANGV-CENLRGSYRCVCNLGYEAGASGKDCT-DVDE 727
Query: 555 CR-SSPCANGGQCQDQPGAFHCKCLPGF---EGPRCQTEVDECLSDPCPVGASCLDLPGA 610
C +S + G CQ+ PG++ C C PGF + +VDECLS PC V C +L G+
Sbjct: 728 CALNSLLCDNGWCQNSPGSYSCSCPPGFHFWQDTEICKDVDECLSSPC-VSGVCRNLAGS 786
Query: 611 FFCLC-------PSG--------------FTGQLCEV----------------------- 626
+ C C PSG CEV
Sbjct: 787 YTCKCGPGSRLDPSGTFCLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPC 846
Query: 627 ------PLCAPNLCQPKQICKDQKDKANC---LCPDGSPGCAPPEDNCTCHHGHCQRSS- 676
P CA + + D ++ +CP+G C C G +S
Sbjct: 847 ERCEIDPACARGFARMTGVTCDDVNECESFPGVCPNGRCVNTAGSFRCECPEGLMLDASG 906
Query: 677 --CV------CDVGWTGPECEAELGG-------CISAPCAHGGTCY----PQPSGYNCTC 717
CV C + W EC L G C S G C P+ + C
Sbjct: 907 RLCVDVRLEPCFLRWDEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLC 966
Query: 718 PTG--------YTGPTCSEEMTACHSGPCL-NGGSCNPSPGGYYCTCPPSHTGPQCQ--- 765
P G +G +++ C P L G+C + G ++C C +
Sbjct: 967 PRGLGFASRDFLSGRPFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNC 1026
Query: 766 TSTDYCVSAPCFNG-GTCVNRPGTFSCLCAMGFQG-----PRCEGKLRPSCADSP--CRN 817
T D C +P G GTCVN PG+F C C G++ C CA P CR
Sbjct: 1027 TDIDECRISPDLCGQGTCVNTPGSFECECFPGYESGFMLMKNCMDV--DECARDPLLCRG 1084
Query: 818 RATCQDSPQGPRCLCPTGY----TGGSCQTLMDLCAQKP--CPRNSHCLQTGPSFHCLCL 871
TC ++ +C CP G+ G +C+ + D C+ CP + C+ +F C C
Sbjct: 1085 -GTCTNTDGSYKCQCPPGHELTAKGTACEDI-DECSLSDGLCP-HGQCVNVIGAFQCSCH 1141
Query: 872 QGWTGPLCNLPLSSCQKAALSQG-IDVSSL-CHNGGL---CVDSGPSYFCHCPPGF---- 922
G+ Q QG +D++ NGG C+++ SY C C G+
Sbjct: 1142 AGF------------QSTPDRQGCVDINECRVQNGGCDVHCINTEGSYRCSCGQGYSLMP 1189
Query: 923 QGSLCQDHVNPCESRP--CQNGATCMAQPSGYLCQCAPGY----DGQNCSKELDACQSQP 976
G C D V+ CE P C G C P G+ C C G+ D + C ++D C P
Sbjct: 1190 DGRACAD-VDECEENPRVCDQG-HCTNMPGGHRCLCYDGFMATPDMRTC-VDVDECDLNP 1246
Query: 977 --------------------------------------------CHNHGTCTPKPGGFHC 992
C +H +C PG F C
Sbjct: 1247 HICLHGDCENTKGSFVCHCQLGYMVRKGATGCSDVDECEVGGHNCDSHASCLNIPGSFSC 1306
Query: 993 ACPPGFV--GLRCEGDVDECLDQP--CHPTGTAACHSLANAFYCQCLPGHTGQ--WCEVE 1046
C PG+V G C D+DEC+ Q C P G C ++ ++ C C G G +CE
Sbjct: 1307 RCLPGWVGDGFECH-DLDECVSQEHRCSPRGD--CLNVPGSYRCTCRQGFAGDGFFCEDR 1363
Query: 1047 IDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSP 1106
+ + G C +P G+ C C GF+ PT HRA C G LC
Sbjct: 1364 DECAENVDLCDNGQC---LNAPGGYRCECEMGFD-PTEDHRACQ-DVDECAQGNLCAFGS 1418
Query: 1107 KPGFPP--RCACLSGY----GGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCS 1160
P RC C GY GG +C C P C+ NG C T G + CS
Sbjct: 1419 CENLPGMFRCICNGGYELDRGGGNCTD---INECADPVNCI-NGVCINTPG----SYLCS 1470
Query: 1161 CPH----SSPGPRCQKPGAKGCEGRSGD-GACDAGCS---GPGGNWDGGDCSLGVP--DP 1210
CP + G C A C + D G CS G G CSLG +P
Sbjct: 1471 CPQDFELNPSGVGCVDTRAGNCFLETHDRGDSGISCSAEIGVGVTRASCCCSLGRAWGNP 1530
Query: 1211 WKGCP-----------------SHSRCWLLFRD-GQCHP---QCDSEECL--FDGYDCET 1247
+ CP +R ++ D +C C +C+ F + CE
Sbjct: 1531 CELCPMANTTEYRTLCPGGEGFQPNRITVILEDIDECQELPGLCQGGDCVNTFGSFQCEC 1590
Query: 1248 PPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRP 1286
PP H H CE + EC G C P
Sbjct: 1591 PPG--------YHLSEHTRICE---DIDECSTHSGICGP 1618
Score = 285 bits (728), Expect = 4e-76
Identities = 348/1306 (26%), Positives = 466/1306 (35%), Gaps = 342/1306 (26%)
Query: 220 CLCPVGQEGPRCELRAGPCPPRGCSNGGTCQ---------------LMPEKDSTFH---- 260
C C G P C + G C NGGTC+ P D H
Sbjct: 101 CTCADGTLAPSCGVSRGSGCSVSCMNGGTCRGASCLCQKGYTGTVCGQPICDRGCHNGGR 160
Query: 261 -----LCLCPPGFIGPDCE-----------VNPDNCVSHQ-----CQNGGTCQD-----G 294
C C GF+GP CE V P+ C HQ C C G
Sbjct: 161 CIGPNRCACVYGFMGPQCERDYRTGPCFGQVGPEGC-QHQLTGLVCTKALCCATVGRAWG 219
Query: 295 LDTYTC----------LCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCV 344
L C P TG +DVDEC Q P GG+C N GSFHC C
Sbjct: 220 LPCELCPAQPHPCRRGFIPNIHTG--ACQDVDEC--QAVPGLCQGGSCVNMVGSFHCRCP 275
Query: 345 SGWGGTSCEENLDDCIAATCAP---GSTCI-DRVGSFS---CLCPPGRTGLLCHLEDMCL 397
G + +D A C G C D G ++ C C GR + ++C
Sbjct: 276 VGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRGRCWAAGPVPELCP 335
Query: 398 SQ-----------------------------------PCHGDAQCSTNPLTGSTLCLCQP 422
+ P G A+ + + + P
Sbjct: 336 PRGSNEFQQLCAQRLPLLPGHPGLFPGLLGFGSNGMGPPLGPARLNPHGSDARGIPSLGP 395
Query: 423 GYSG---PTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGS-RCEA-DHN 477
G S T +Q +D C + + C + G CL TP S+ C C GYT R E D +
Sbjct: 396 GNSNIGTATLNQTIDIC---RHFTNLCLN-GRCLPTPSSYRCECNVGYTQDVRGECIDVD 451
Query: 478 ECLSQPCHPGSTCLDLLATFHCLCPPGLEG----QLCEVETNECASAPCLNH-ADCHDLL 532
EC S PCH G C+++ T+HC C PG + Q C V+ +EC + L H C +
Sbjct: 452 ECTSSPCHHGD-CVNIPGTYHCRCYPGFQATPTRQAC-VDVDECIVSGGLCHLGRCVNTE 509
Query: 533 NGFQCICLPGF----SGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGF---EGPR 585
FQC+C GF G C D +EC +S G C ++ G+F C C PGF G
Sbjct: 510 GSFQCVCNAGFELSPDGKNC-VDHNECATSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGH 568
Query: 586 CQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFT----GQLCEVPLCAPNLCQ---PKQ 638
++DEC + V C + G+F C C G G++C V + C K
Sbjct: 569 YCMDIDECQTPGICVNGHCTNTEGSFRCQCLGGLAVGTDGRVC-VDTHVRSTCYGAIEKG 627
Query: 639 IC----KDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGG 694
C K+ C C + G P C ++ C +G T ++
Sbjct: 628 SCARPFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQALCSSGLGITTD--GRDINE 685
Query: 695 CISAP--CAHGGTCYPQPSGYNCTCPTGY----TGPTCSEEMTACHSGPCLNGGSCNPSP 748
C P CA+ G C Y C C GY +G C++ + + G C SP
Sbjct: 686 CALDPEVCAN-GVCENLRGSYRCVCNLGYEAGASGKDCTDVDECALNSLLCDNGWCQNSP 744
Query: 749 GGYYCTCPPSH---TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMG--------- 796
G Y C+CPP + D C+S+PC + G C N G+++C C G
Sbjct: 745 GSYSCSCPPGFHFWQDTEICKDVDECLSSPCVS-GVCRNLAGSYTCKCGPGSRLDPSGTF 803
Query: 797 ------------FQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC----LCPTGY---T 837
Q RCE L+ + S C RC C G+ T
Sbjct: 804 CLDSTKGTCWLKIQESRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMT 863
Query: 838 GGSCQTLMDLCAQKP--CPRNSHCLQTGPSFHCLCLQG---------------------W 874
G +C + + C P CP N C+ T SF C C +G W
Sbjct: 864 GVTCDDVNE-CESFPGVCP-NGRCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRW 921
Query: 875 TGPLCNLPLS------------------SCQKAALSQGIDVSSLCHNG------------ 904
C + L C+ + ++ +SLC G
Sbjct: 922 DEDECGVTLPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGR 981
Query: 905 ------------------GLCVDSGPSYFCHCPPGF----QGSLCQDHVNPCESRP--CQ 940
G C ++ S+ C C GF Q C D ++ C P C
Sbjct: 982 PFYKDVNECKVFPGLCTHGTCRNTVGSFHCACAGGFALDAQERNCTD-IDECRISPDLCG 1040
Query: 941 NGATCMAQPSGYLCQCAPGYDG-----QNCSKELDACQSQP--CHNHGTCTPKPGGFHCA 993
G TC+ P + C+C PGY+ +NC ++D C P C GTCT G + C
Sbjct: 1041 QG-TCVNTPGSFECECFPGYESGFMLMKNC-MDVDECARDPLLCRG-GTCTNTDGSYKCQ 1097
Query: 994 CPPGF----VGLRCEGDVDEC-LDQPCHPTGTAACHSLANAFYCQCLPGHTG----QWCE 1044
CPPG G CE D+DEC L P G C ++ AF C C G Q C
Sbjct: 1098 CPPGHELTAKGTACE-DIDECSLSDGLCPHG--QCVNVIGAFQCSCHAGFQSTPDRQGC- 1153
Query: 1045 VEIDPCHSQPCFHGGT---CEATAGSPLGFICHCPKGF----------EGPTCSHRAPSC 1091
V+I+ C Q +GG C T GS + C C +G+ + C C
Sbjct: 1154 VDINECRVQ---NGGCDVHCINTEGS---YRCSCGQGYSLMPDGRACADVDECEENPRVC 1207
Query: 1092 GFHHCHHGGLCLPSPKPGFPPRCACLSGY-GGPDCLTPPAPKGCG-PPSPCLYNGSCSET 1149
HC + PG RC C G+ PD T C P CL+ G C T
Sbjct: 1208 DQGHC--------TNMPG-GHRCLCYDGFMATPDMRTCVDVDECDLNPHICLH-GDCENT 1257
Query: 1150 TGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPD 1209
G F C C G +K GA GC S C+ G G N D L +P
Sbjct: 1258 KG----SFVCHC---QLGYMVRK-GATGC---SDVDECEVG----GHNCDSHASCLNIPG 1302
Query: 1210 PWKGCPSHSRC---WLLFRDG-QCHPQCDSEECLFDGYDCETPPAC 1251
+ RC W+ DG +CH D +EC+ + C C
Sbjct: 1303 SFS-----CRCLPGWV--GDGFECH---DLDECVSQEHRCSPRGDC 1338
Score = 271 bits (694), Expect = 4e-72
Identities = 275/996 (27%), Positives = 374/996 (37%), Gaps = 267/996 (26%)
Query: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGF----LGETCQFPDPCQNAQL-CQNGGSCQA 82
CG P CAN G C++ +G C+C GF + C+ D C + + CQ C
Sbjct: 1725 CGEIPAICAN-GICIN-QIGSFRCECPAGFNYNSILLACEDVDECGSRESPCQQNADC-- 1780
Query: 83 LLPAPLGLPSSPSPLTPSFLCTCLPGF---TGERCQAKLEDPCPPSFCSKRGRCHIQASG 139
+ +P S+ C C G+ G C + E P+ CS G C + G
Sbjct: 1781 -----INIPG-------SYRCKCTRGYKLSPGGACVGRNECREIPNVCS-HGDC-MDTEG 1826
Query: 140 RPQCSCMPGWTGEQ----CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGF---EGHACE 192
C C G+ C D C PC N G C C C PGF C
Sbjct: 1827 SYMCLCHRGFQASADQTLCMDIDECDRQPCGN-GTCKNIIGSYNCLCFPGFVVTHNGDCV 1885
Query: 193 RDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQE----------GPRCELRAGPCPPRG 242
D +EC G + C NT GSF CLC G E C AG C P
Sbjct: 1886 -DFDECTTLVGQVCRFGHCLNTAGSFHCLCQDGFELTADGKNCVDTNECLSLAGTCLP-- 1942
Query: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVS-HQCQNG------GTCQDGL 295
GTCQ + + +F C+CPPGF +V D+C+ +C GTC +
Sbjct: 1943 ----GTCQNL---EGSFR-CICPPGF-----QVQSDHCIDIDECSEEPNLCLFGTCTNSP 1989
Query: 296 DTYTCLCPETWTGWDCSEDVDECETQGPPHC---RNGGTC-------------------- 332
++ CLCP G+ S++ C C G C
Sbjct: 1990 GSFQCLCP---PGFVLSDNGHRCFDTRQSFCFTRFEAGKCSVPKAFNTTKTRCCCSKRPG 2046
Query: 333 -----------QNSAGSFHCVCVSGWGGT----SCEENLDDCI--AATCAPGSTCIDRVG 375
Q + +F +C G G E++++C C G C++ G
Sbjct: 2047 EGWGDPCELCPQEGSAAFQELCPFGHGAVPGPDDSREDVNECAENPGVCTNG-VCVNTDG 2105
Query: 376 SFSCLCPPGR----TGLLCHLEDMC-LSQPCHGDAQCSTNPLTGSTLCLCQPGYSG---P 427
SF C CP G TG+ C D C + PC G C+ + G C C G+
Sbjct: 2106 SFRCECPFGYSLDFTGINCVDTDECSVGHPC-GQGTCTN--VIGGFECACADGFEPGLMM 2162
Query: 428 TCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT----GSRCEADHNECL--S 481
TC +D+DEC + +P C NT GS+ C CP GYT G+ C D +EC
Sbjct: 2163 TC-EDIDECSL-----NPLLCAFRCHNTEGSYLCTCPAGYTLREDGAMCR-DVDECADGQ 2215
Query: 482 QPCHP-GSTCLDLLATFHCLCPPGL-----EGQLCEVETNECASAP-------CLNHA-- 526
Q CH G C +L+ TF C+CPPG+ G+ C + NEC + P C+N A
Sbjct: 2216 QDCHARGMECKNLIGTFACVCPPGMRPLPGSGEGC-TDDNECHAQPDLCVNGRCVNTAGS 2274
Query: 527 ----------------DCHDLLNG-----------------------FQCICLPGFS-GT 546
+CHD+ G +C C G G
Sbjct: 2275 FRCDCDEGFQPSPTLTECHDIRQGPCFAEVLQTMCRSLSSSSEAVTRAECCCGGGRGWGP 2334
Query: 547 RCE------------------------EDIDECR--SSPCANGGQCQDQPGAFHCKCLPG 580
RCE D+DECR + CA+ G+C + G+F C C G
Sbjct: 2335 RCELCPLPGTSAYRKLCPHGSGYTAEGRDVDECRMLAHLCAH-GECINSLGSFRCHCQAG 2393
Query: 581 FEGPRCQT---EVDECLSDPCPVGASCLDLPGAFFCLCPSGF----TGQLC-EVPLCAPN 632
+ T ++DEC P P C + G+F C CP G+ G+ C ++ C
Sbjct: 2394 YTPDATATTCLDMDECSQVPKPCTFLCKNTKGSFLCSCPRGYLLEEDGRTCKDLDECTSR 2453
Query: 633 LCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAEL 692
+ +C + C CP G T HH C + EC A+
Sbjct: 2454 QHNCQFLCVNTVGAFTCRCPPG----------FTQHHQAC----------FDNDECSAQP 2493
Query: 693 GGCISAPCAHGGTCYPQPSGYNCTCPTGYT----GPTCSEEMTACHSGPCLNGGSCNPSP 748
G PC G C+ P + C C G+T G C E++ C GP C
Sbjct: 2494 G-----PCGAHGHCHNTPGSFRCECHQGFTLVSSGHGC-EDVNEC-DGPHRCQHGCQNQL 2546
Query: 749 GGYYCTCPPSHT----GPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEG 804
GGY C+CP T QC + +S P +C N G F C+C GF + G
Sbjct: 2547 GGYRCSCPQGFTQHSQWAQCVDENECALSPPTCGSASCRNTLGGFRCVCPSGFDFDQALG 2606
Query: 805 KLR--PSCAD--SPCRNRATCQDSPQGPRCLCPTGY 836
+ CA PC +C ++P G C CP GY
Sbjct: 2607 GCQEVDECAGRRGPC--SYSCANTPGGFLCGCPQGY 2640
Score = 210 bits (535), Expect = 1e-53
Identities = 305/1220 (25%), Positives = 418/1220 (34%), Gaps = 279/1220 (22%)
Query: 222 CPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCV 281
CP + P P R C G Q +LC C G + P C V+ +
Sbjct: 69 CPGWRTFPGRSQCVVPICRRACGEGFCSQP--------NLCTCADGTLAPSCGVSRGSGC 120
Query: 282 SHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHC 341
S C NGGTC+ +CLC + +TG C + + C+ C NGG C G C
Sbjct: 121 SVSCMNGGTCRGA----SCLCQKGYTGTVCGQPI--CDR----GCHNGGRC---IGPNRC 167
Query: 342 VCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPC 401
CV G+ G CE + C +VG C TGL+C C +
Sbjct: 168 ACVYGFMGPQCERDYRT---------GPCFGQVGPEG--CQHQLTGLVCTKALCCATVGR 216
Query: 402 HGDAQCSTNPLTGSTLCLCQPGYSGPTCH----QDLDECLMAQQGPSPCEHGGSCLNTPG 457
C P C+ G+ P H QD+DEC Q P C+ GGSC+N G
Sbjct: 217 AWGLPCELCPAQPHP---CRRGFI-PNIHTGACQDVDEC---QAVPGLCQ-GGSCVNMVG 268
Query: 458 SFNCLCPPGYTGSRCEADHNECLSQPCHP---GSTCLDLLATFHC--------------- 499
SF+C CP G+ S A + + C G C LA +
Sbjct: 269 SFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRGRCWAAG 328
Query: 500 ----LCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICL--------------- 540
LCPP + ++ P H L GF +
Sbjct: 329 PVPELCPPRGSNEFQQLCAQRLPLLP--GHPGLFPGLLGFGSNGMGPPLGPARLNPHGSD 386
Query: 541 --------PGFSG---TRCEEDIDECR--SSPCANGGQCQDQPGAFHCKCLPGFEGP--- 584
PG S + ID CR ++ C N G+C P ++ C+C G+
Sbjct: 387 ARGIPSLGPGNSNIGTATLNQTIDICRHFTNLCLN-GRCLPTPSSYRCECNVGYTQDVRG 445
Query: 585 RCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQK 644
C +VDEC S PC G C+++PG + C C GF +Q C D
Sbjct: 446 EC-IDVDECTSSPCHHG-DCVNIPGTYHCRCYPGF------------QATPTRQACVDVD 491
Query: 645 DKANCLCPDGSPGCAPPEDNCTCHHGHCQRS----SCVCDVGW----TGPECEAELGGCI 696
+ C+ G CH G C + CVC+ G+ G C + C
Sbjct: 492 E---CIVSGG-----------LCHLGRCVNTEGSFQCVCNAGFELSPDGKNC-VDHNECA 536
Query: 697 SAPCAHGGTCYPQPSGYNCTCPTGYT----GPTCSEEMTACHSGPCLNGGSCNPSPGGYY 752
++ G C + ++C C G+ G C + G C+N G C + G +
Sbjct: 537 TSTMCVNGVCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICVN-GHCTNTEGSFR 595
Query: 753 CTCPPS-HTGPQCQTSTDYCVSAPCFNG---GTCVNR-PGTFS---CLCA---MGFQGPR 801
C C G + D V + C+ G+C PGT + C CA GF P
Sbjct: 596 CQCLGGLAVGTDGRVCVDTHVRSTCYGAIEKGSCARPFPGTVTKSECCCANPDHGFGEP- 654
Query: 802 CEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQ 861
C P ++ A Q + G C ++CA N C
Sbjct: 655 --------CQLCPAKDSAEFQALCSSGLGITTDGRDINECALDPEVCA------NGVCEN 700
Query: 862 TGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPG 921
S+ C+C G+ + + AL+ S LC N G C +S SY C CPPG
Sbjct: 701 LRGSYRCVCNLGYEAGASGKDCTDVDECALN-----SLLCDN-GWCQNSPGSYSCSCPPG 754
Query: 922 F----QGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPG------------------ 959
F +C+D V+ C S PC +G C Y C+C PG
Sbjct: 755 FHFWQDTEICKD-VDECLSSPCVSG-VCRNLAGSYTCKCGPGSRLDPSGTFCLDSTKGTC 812
Query: 960 ---YDGQNCSKELD--ACQSQPCHNHGTCTPKP---GGFHCACPPGF---VGLRCEGDVD 1008
C L + +S+ C G P AC GF G+ C+ DV+
Sbjct: 813 WLKIQESRCEVNLQGASLRSECCATLGAAWGSPCERCEIDPACARGFARMTGVTCD-DVN 871
Query: 1009 ECLDQP-CHPTGTAACHSLANAFYCQCLPG----HTGQWC-EVEIDPCH----------- 1051
EC P P G C + A +F C+C G +G+ C +V ++PC
Sbjct: 872 ECESFPGVCPNG--RCVNTAGSFRCECPEGLMLDASGRLCVDVRLEPCFLRWDEDECGVT 929
Query: 1052 ------------SQPCFHGGTCEATAG-SPLGFICHCPKGF---EGPTCSHRAPSCGFHH 1095
S G CEA L F CP+G S R +
Sbjct: 930 LPGKYRMDVCCCSIGAVWGVECEACPDPESLEFASLCPRGLGFASRDFLSGRPFYKDVNE 989
Query: 1096 CH-HGGLCLPSPKPGFPP--RCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGS-CSETTG 1151
C GLC CAC G+ + C C + C + T
Sbjct: 990 CKVFPGLCTHGTCRNTVGSFHCACAGGFA-----LDAQERNCTDIDECRISPDLCGQGTC 1044
Query: 1152 LGGPG-FRCSC-PHSSPGPRCQKPGAKGCEGRSGDGACDAG-CSGPGGNWDGGDCSLGVP 1208
+ PG F C C P G K E C G C+ G++ C G
Sbjct: 1045 VNTPGSFECECFPGYESGFMLMKNCMDVDECARDPLLCRGGTCTNTDGSYK-CQCPPGHE 1103
Query: 1209 DPWKG--CPSHSRCWLLFRDGQC-HPQCDSEECLFDGYDCETPPACTPAYDQYCHDHFHN 1265
KG C C L DG C H QC + + + C CH F +
Sbjct: 1104 LTAKGTACEDIDECSL--SDGLCPHGQCVN---VIGAFQCS------------CHAGFQS 1146
Query: 1266 GHCEKGC-NTAECGWDGGDC 1284
+GC + EC G C
Sbjct: 1147 TPDRQGCVDINECRVQNGGC 1166
Score = 164 bits (414), Expect = 1e-39
Identities = 233/925 (25%), Positives = 308/925 (33%), Gaps = 230/925 (24%)
Query: 441 QGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCL 500
QGP+ C GS F+ C PG+ R ++C+ C C
Sbjct: 55 QGPNVC---GS------RFHAYCCPGW---RTFPGRSQCVVPICRRACGEGFCSQPNLCT 102
Query: 501 CPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPC 560
C G C V S C+N C G C+C G++GT C + I + C
Sbjct: 103 CADGTLAPSCGVSRGSGCSVSCMNGGTCR----GASCLCQKGYTGTVCGQPICD---RGC 155
Query: 561 ANGGQCQDQPGAFHCKCLPGFEGPRCQTE--VDECLSDPCPVGASCLDLPGAFFCLCPSG 618
NGG+C G C C+ GF GP+C+ + C P G C
Sbjct: 156 HNGGRC---IGPNRCACVYGFMGPQCERDYRTGPCFGQVGPEG-------------CQHQ 199
Query: 619 FTGQLCEVPLCAPNLCQ----PKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQR 674
TG +C LC + + P ++C Q G P H G CQ
Sbjct: 200 LTGLVCTKALCCATVGRAWGLPCELCPAQPHPCR-------RGFIP-----NIHTGACQ- 246
Query: 675 SSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACH 734
DV EC+A G C GG+C ++C CP G+ S
Sbjct: 247 -----DV----DECQAVPGLC------QGGSCVNMVGSFHCRCPVGHRLSDSSAACEDYR 291
Query: 735 SGPC---LNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAP-----CFNGGT----- 781
+G C L GG C G+Y T QC C +A C G+
Sbjct: 292 AGACFSVLFGGRCAGDLAGHY-------TRRQCCCDRGRCWAAGPVPELCPPRGSNEFQQ 344
Query: 782 -CVNR-------PGTFSCLCAMGFQG---PRCEGKLRPSCADSP---------------- 814
C R PG F L G G P +L P +D+
Sbjct: 345 LCAQRLPLLPGHPGLFPGLLGFGSNGMGPPLGPARLNPHGSDARGIPSLGPGNSNIGTAT 404
Query: 815 -------CRN------RATCQDSPQGPRCLCPTGYT---GGSCQTLMDLCAQKPCPRNSH 858
CR+ C +P RC C GYT G C +D C PC +
Sbjct: 405 LNQTIDICRHFTNLCLNGRCLPTPSSYRCECNVGYTQDVRGECID-VDECTSSPC-HHGD 462
Query: 859 CLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHC 918
C+ ++HC C G+ + +S G LCH G CV++ S+ C C
Sbjct: 463 CVNIPGTYHCRCYPGFQATPTRQACVDVDECIVSGG-----LCHL-GRCVNTEGSFQCVC 516
Query: 919 PPGFQ----GSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGY---DGQNCSKELDA 971
GF+ G C DH S C NG C+ + + C C PG+ G + ++D
Sbjct: 517 NAGFELSPDGKNCVDHNECATSTMCVNG-VCLNEDGSFSCLCKPGFLLAPGGHYCMDIDE 575
Query: 972 CQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFY 1031
CQ+ +G CT G F C C GL D C+D T C+
Sbjct: 576 CQTPGICVNGHCTNTEGSFRCQC---LGGLAVGTDGRVCVDTHVRST----CYGAIEKGS 628
Query: 1032 C-QCLPGHT--GQWCEVEID-----PCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPT 1083
C + PG + C D PC P +A S LG G +
Sbjct: 629 CARPFPGTVTKSECCCANPDHGFGEPCQLCPAKDSAEFQALCSSGLGI---TTDGRDINE 685
Query: 1084 CSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGY----GGPDCLTPPAPKGCGPPSP 1139
C+ C G+C + + + RC C GY G DC C S
Sbjct: 686 CALDPEVCA------NGVC-ENLRGSY--RCVCNLGYEAGASGKDCTDVDE---CALNSL 733
Query: 1140 CLYNGSCSETTGLGGPGFRCSCPHSSPG-------------PRC-QKPGAKG-CEGRSGD 1184
NG C + G + CSCP PG C P G C +G
Sbjct: 734 LCDNGWCQNSPG----SYSCSCP---PGFHFWQDTEICKDVDECLSSPCVSGVCRNLAGS 786
Query: 1185 GACDAGCSGPGGNWD--GGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCD-----SEE 1237
C GPG D G C D KG CWL ++ +C SE
Sbjct: 787 YTCKC---GPGSRLDPSGTFCL----DSTKG-----TCWLKIQESRCEVNLQGASLRSEC 834
Query: 1238 CLFDG-------YDCETPPACTPAY 1255
C G CE PAC +
Sbjct: 835 CATLGAAWGSPCERCEIDPACARGF 859
Score = 136 bits (342), Expect = 2e-31
Identities = 172/602 (28%), Positives = 220/602 (36%), Gaps = 123/602 (20%)
Query: 630 APNLCQPKQICKDQKDKANCLCPD-----GSPGCAPPEDNCTCHHGHC-QRSSCVCDVGW 683
+P + Q +C + A C CP G C P C G C Q + C C G
Sbjct: 50 SPGILQGPNVC-GSRFHAYC-CPGWRTFPGRSQCVVPICRRACGEGFCSQPNLCTCADGT 107
Query: 684 TGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGS 743
P C G S C +GGTC G +C C GYTG C + + C G C NGG
Sbjct: 108 LAPSCGVSRGSGCSVSCMNGGTC----RGASCLCQKGYTGTVCGQPI--CDRG-CHNGGR 160
Query: 744 CNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCE 803
C G C C GPQC+ DY + PCF V G C G C
Sbjct: 161 C---IGPNRCACVYGFMGPQCE--RDY-RTGPCFGQ---VGPEG-----CQHQLTGLVCT 206
Query: 804 GKLRPSCADSPCRNRATCQDSPQGP----RCLCPTGYTGGSCQTLMDLCAQKPCPRNSHC 859
L CA C+ P P R P +T G+CQ + + A + C
Sbjct: 207 KAL--CCATVGRAWGLPCELCPAQPHPCRRGFIPNIHT-GACQDVDECQAVPGLCQGGSC 263
Query: 860 LQTGPSFHCLCLQGW----TGPLCNLPLSSCQKAALSQGIDVSSL---------CHNGGL 906
+ SFHC C G + C + + L G L C + G
Sbjct: 264 VNMVGSFHCRCPVGHRLSDSSAACEDYRAGACFSVLFGGRCAGDLAGHYTRRQCCCDRGR 323
Query: 907 CVDSGPSYFCHCPP----GFQGSLCQDHVNPCESRP------CQNGATCMAQPSGYLCQC 956
C +GP CPP FQ LC + P G+ M P G
Sbjct: 324 CWAAGPVPEL-CPPRGSNEFQ-QLCAQRLPLLPGHPGLFPGLLGFGSNGMGPPLGPARLN 381
Query: 957 APGYDGQ---------------NCSKELDACQ--SQPCHNHGTCTPKPGGFHCACPPGFV 999
G D + ++ +D C+ + C N G C P P + C C G+
Sbjct: 382 PHGSDARGIPSLGPGNSNIGTATLNQTIDICRHFTNLCLN-GRCLPTPSSYRCECNVGYT 440
Query: 1000 -GLRCEG-DVDECLDQPCHPTGTAACHSLANAFYCQCLPGH----TGQWCEVEIDPC-HS 1052
+R E DVDEC PCH C ++ ++C+C PG T Q C V++D C S
Sbjct: 441 QDVRGECIDVDECTSSPCH---HGDCVNIPGTYHCRCYPGFQATPTRQAC-VDVDECIVS 496
Query: 1053 QPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHH-CHHGGLCLPSPKPGFP 1111
H G C T GS F C C GFE S +C H+ C +C+
Sbjct: 497 GGLCHLGRCVNTEGS---FQCVCNAGFE---LSPDGKNCVDHNECATSTMCVNG------ 544
Query: 1112 PRCACLSGYGGPDCLTPP----APKG--------CGPPSPCLYNGSCSETTGLGGPGFRC 1159
CL+ G CL P AP G C P C+ NG C+ T G FRC
Sbjct: 545 ---VCLNEDGSFSCLCKPGFLLAPGGHYCMDIDECQTPGICV-NGHCTNTEG----SFRC 596
Query: 1160 SC 1161
C
Sbjct: 597 QC 598
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 337 bits (863), Expect = 9e-92
Identities = 392/1465 (26%), Positives = 545/1465 (37%), Gaps = 345/1465 (23%)
Query: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLG------------ETCQFPDPCQNAQLCQ 75
C FP C NG C++ + G CQC G ETC + L
Sbjct: 914 CEVFPGVCKNG-LCVN-TRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPI 971
Query: 76 NG----GSCQALLPAPLGLPSS---PSPLTPSF--LCTCLPGF-----TGERCQAKLEDP 121
G +C + A G P TP + LC PGF T + K +
Sbjct: 972 AGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINE 1031
Query: 122 CP--PSFCSKRGRCHIQASGRPQCSCMPGWTGEQ----CQLRDFCSANPCVNG-GVCLAT 174
C PS C+ G+C G +C C G+ + C D C +P + G G C+ T
Sbjct: 1032 CKMIPSLCT-HGKCR-NTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNT 1089
Query: 175 YPQIQCHCPPGFEGHACER----DVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQE-GP 229
+C C G+E D++EC +DP C +G CHNT GS++C CP G + P
Sbjct: 1090 PGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLC-RGGVCHNTEGSYRCECPPGHQLSP 1148
Query: 230 R---------CELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIG-PD---CEVN 276
CEL A CP NG L+ + + C C PG+ PD C V+
Sbjct: 1149 NISACIDINECELSAHLCP-----NGRCVNLIGK-----YQCACNPGYHSTPDRLFC-VD 1197
Query: 277 PDNCVSHQCQNGGT---CQDGLDTYTCLCPETWTGW----DCSEDVDECETQGPPHCRNG 329
D C NGG C + +Y C C + C+ D+DECE P+ +G
Sbjct: 1198 IDEC---SIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCT-DIDECEDN--PNICDG 1251
Query: 330 GTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLL 389
G C N G + C+C G+ E++ C+ C P
Sbjct: 1252 GQCTNIPGEYRCLCYDGF---MASEDMKTCVDVN--------------ECDLNP------ 1288
Query: 390 CHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGP---TCHQDLDECLMAQQGPSPC 446
++CLS C GS +C C GYSG T D++EC + G C
Sbjct: 1289 ----NICLSGTCENTK--------GSFICHCDMGYSGKKGKTGCTDINEC---EIGAHNC 1333
Query: 447 EHGGSCLNTPGSFNCLCPPGYTGS--RCEADHNECL--SQPCHPGSTCLDLLATFHCLCP 502
C NT GSF C C PG+ G +C D +EC + C + C + + ++ CLC
Sbjct: 1334 GKHAVCTNTAGSFKCSCSPGWIGDGIKC-TDLDECSNGTHMCSQHADCKNTMGSYRCLCK 1392
Query: 503 PGLEG--------QLCEVETNECASAPCLNHADCHDLLNGFQCIC----LPGFSGTRCEE 550
G G C N C + CLN G++C C +P G C E
Sbjct: 1393 EGYTGDGFTCTDLDECSENLNLCGNGQCLNAP------GGYRCECDMGFVPSADGKAC-E 1445
Query: 551 DIDECRSSPCANGGQCQDQPGAFHCKCLPGFE----GPRCQTEVDECLSDPCPVGASCLD 606
DIDEC G C + PG F C+C G+E G C T+V+ECL + +C++
Sbjct: 1446 DIDECSLPNICVFGTCHNLPGLFRCECEIGYELDRSGGNC-TDVNECLDPTTCISGNCVN 1504
Query: 607 LPGAFFCLCPSGFTGQLCEVPL-----------CAPNLCQPKQICKDQ----KDKANCLC 651
PG++ C CP F V P C ++ KA+C C
Sbjct: 1505 TPGSYICDCPPDFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCC 1564
Query: 652 PDGS---------PGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAH 702
G P E C G R + + + EC+ G C
Sbjct: 1565 SLGKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLC------Q 1618
Query: 703 GGTCYPQPSGYNCTCPTGY---TGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSH 759
GG C + C CPTGY +++ C + G+C + G Y C CPP +
Sbjct: 1619 GGKCINTFGSFQCRCPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGNYTCICPPDY 1678
Query: 760 T----GPQCQT-------STDYCVSAPC----------------FNGGTCVNRP------ 786
G C Y + C +N G N+P
Sbjct: 1679 MQVNGGNNCMDMRRSLCYRNYYADNQTCDGELLFNMTKKMCCCSYNIGRAWNKPCEQCPI 1738
Query: 787 ---GTFSCLCAMGFQGPRCEGKLR-------PSCADSP--CRNRATCQDSPQGPRCLCPT 834
F+ LC G Q P + C + P C N C + RC CP
Sbjct: 1739 PSTDEFATLC--GSQRPGFVIDIYTGLPVDIDECREIPGVCEN-GVCINMVGSFRCECPV 1795
Query: 835 GYTGGS----CQTLMDLCAQKP-CPRNSHCLQTGPSFHCLCLQGW----TGPLCNLPLSS 885
G+ C+ + D C P C RN+ C+ T S+ C C G+ TG CN +
Sbjct: 1796 GFFYNDKLLVCEDI-DECQNGPVCQRNAECINTAGSYRCDCKPGYRFTSTGQ-CN-DRNE 1852
Query: 886 CQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ----GSLCQDHVNPCESRPCQN 941
CQ ++ ++C + G C+D+ S++C C GF+ ++C D +N CE C N
Sbjct: 1853 CQ--------EIPNICSH-GQCIDTVGSFYCLCHTGFKTNDDQTMCLD-INECERDACGN 1902
Query: 942 GATCMAQPSGYLCQCAPGY--DGQNCSKELDACQS---QPCHNHGTCTPKPGGFHCACPP 996
G TC + C+C G+ N ++D C S C N G C G F C C
Sbjct: 1903 G-TCRNTIGSFNCRCNHGFILSHNNDCIDVDECASGNGNLCRN-GQCINTVGSFQCQCNE 1960
Query: 997 GFV----GLRCEGDVDECLDQP--CHPTGTAACHSLANAFYCQCLPGHT--GQWCEVEID 1048
G+ G C D++ECL +P C P C +L ++ C C PG++ + CE +ID
Sbjct: 1961 GYEVAPDGRTCV-DINECLLEPRKCAP---GTCQNLDGSYRCICPPGYSLQNEKCE-DID 2015
Query: 1049 PCHSQPCFHG-GTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCH---HGGLC-L 1103
C +P GTC T GS F C CP+GF + R +C+ GG C
Sbjct: 2016 ECVEEPEICALGTCSNTEGS---FKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSS 2072
Query: 1104 PSPKPGFPPRCACL---SGYGGPDCLTPPAP-------------------------KGCG 1135
P + C C G+G P L P P C
Sbjct: 2073 PKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECK 2132
Query: 1136 PPSPCLYNGSCSETTGLGGPGFRCSCP--HSSPGPRCQKPGAKGCEGRSGDGACDAGCSG 1193
P C + G C T G +RC CP + G C G+G C
Sbjct: 2133 EPDVCKH-GQCINTDG----SYRCECPFGYILAGNECVDTDECSVGNPCGNGTCK----- 2182
Query: 1194 PGGNWDGG---DCSLGV-PDPWKGCPSHSRCWLLFRDGQCHPQCDSEECL--FDGYDCET 1247
N GG C G P P C + C +P + C+ + Y+C+
Sbjct: 2183 ---NVIGGFECTCEEGFEPGPMMTCEDINEC-------AQNPLLCAFRCVNTYGSYECKC 2232
Query: 1248 PPACTPAYD-QYCHDHFHNGHCEKG 1271
P D + C D CE+G
Sbjct: 2233 PVGYVLREDRRMCKD---EDECEEG 2254
Score = 334 bits (856), Expect = 6e-91
Identities = 377/1379 (27%), Positives = 535/1379 (38%), Gaps = 313/1379 (22%)
Query: 35 CANGGTCLSLSLGQGTCQCAPGFL----GETCQFPDPCQNAQLC---------------- 74
C NG CL+ G C+C GF+ G+ C+ D C +C
Sbjct: 1415 CGNG-QCLNAPGGY-RCECDMGFVPSADGKACEDIDECSLPNICVFGTCHNLPGLFRCEC 1472
Query: 75 -------QNGGSCQALLPA--PLGLPSSPSPLTP-SFLCTCLPGFTGERCQAKLEDPCPP 124
++GG+C + P S TP S++C C P F + D
Sbjct: 1473 EIGYELDRSGGNCTDVNECLDPTTCISGNCVNTPGSYICDCPPDFELNPTRVGCVD---- 1528
Query: 125 SFCSKRGRCHIQASGR------------------PQCSCMPG--WTGEQCQLRDFCSANP 164
++ G C++ R C C G W G C++ C P
Sbjct: 1529 ---TRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAW-GTPCEM---C---P 1578
Query: 165 CVNGGVCLATYPQIQCHCPPGFEGHACE---RDVNECFQDPGPCPKGTSCHNTLGSFQCL 221
VN + +I C GF + D++EC + PG C +G C NT GSFQC
Sbjct: 1579 AVN-----TSEYKILCPGGEGFRPNPITVILEDIDECQELPGLC-QGGKCINTFGSFQCR 1632
Query: 222 CPVG---QEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFI----GPDC- 273
CP G E R C G GTC + C+CPP ++ G +C
Sbjct: 1633 CPTGYYLNEDTRVCDDVNECETPGICGPGTCYNTVGN----YTCICPPDYMQVNGGNNCM 1688
Query: 274 EVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQ 333
++ C + + TC L L T CS ++ + C T +
Sbjct: 1689 DMRRSLCYRNYYADNQTCDGEL-----LFNMTKKMCCCSYNIGRAWNKPCEQCPIPSTDE 1743
Query: 334 NSAGSFHCVCVSGWGG------TSCEENLDDC--IAATCAPGSTCIDRVGSFSCLCPPG- 384
F +C S G T ++D+C I C G CI+ VGSF C CP G
Sbjct: 1744 -----FATLCGSQRPGFVIDIYTGLPVDIDECREIPGVCENG-VCINMVGSFRCECPVGF 1797
Query: 385 ---RTGLLCHLEDMCLSQP-CHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQ--DLDECLM 438
L+C D C + P C +A+C GS C C+PGY + Q D +EC
Sbjct: 1798 FYNDKLLVCEDIDECQNGPVCQRNAECINT--AGSYRCDCKPGYRFTSTGQCNDRNEC-- 1853
Query: 439 AQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEA---DHNECLSQPCHPGSTCLDLLA 495
Q+ P+ C HG C++T GSF CLC G+ + + D NEC C G TC + +
Sbjct: 1854 -QEIPNICSHG-QCIDTVGSFYCLCHTGFKTNDDQTMCLDINECERDACGNG-TCRNTIG 1910
Query: 496 TFHCLCPPGL---EGQLCEVETNECASAP---CLNHADCHDLLNGFQCICLPGFS----G 545
+F+C C G C ++ +ECAS C N C + + FQC C G+ G
Sbjct: 1911 SFNCRCNHGFILSHNNDC-IDVDECASGNGNLCRN-GQCINTVGSFQCQCNEGYEVAPDG 1968
Query: 546 TRCEEDIDECRSSP--CANGGQCQDQPGAFHCKCLPGF--EGPRCQTEVDECLSDP--CP 599
C DI+EC P CA G CQ+ G++ C C PG+ + +C+ ++DEC+ +P C
Sbjct: 1969 RTCV-DINECLLEPRKCAPG-TCQNLDGSYRCICPPGYSLQNEKCE-DIDECVEEPEICA 2025
Query: 600 VGASCLDLPGAFFCLCPSGFT---------------------GQLCEVPLCAPNLCQ--- 635
+G +C + G+F CLCP GF+ G C P + Q
Sbjct: 2026 LG-TCSNTEGSFKCLCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECC 2084
Query: 636 ----------PKQICKDQKDKA-NCLCPDGSPGCAPPEDNCT----------CHHGHCQR 674
P ++C + D+A +CP GS P+D+ C HG C
Sbjct: 2085 CALKGEGWGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCIN 2144
Query: 675 SS----CVCDVGW--TGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYT-GP--T 725
+ C C G+ G EC + PC +G TC G+ CTC G+ GP T
Sbjct: 2145 TDGSYRCECPFGYILAGNECVDTDECSVGNPCGNG-TCKNVIGGFECTCEEGFEPGPMMT 2203
Query: 726 CSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHT----------GPQCQTSTDYCVSAP 775
C E++ C P L C + G Y C CP + +C+ C
Sbjct: 2204 C-EDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECEEGKHDCTEKQ 2262
Query: 776 CFNGGTCVNRPGTFSCLCAMGFQG-PRCEGKLRPS-CADSP--CRNRATCQDSPQGPRCL 831
C N GT+ C+C G+Q P EG + + C P C N C ++ C
Sbjct: 2263 M----ECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKPGICEN-GRCLNTRGSYTCE 2317
Query: 832 CPTGYTG------------GSCQT--LMDLCA-----QKPCPRNSHCLQTGPSF--HC-L 869
C G+T G C T L ++C + P ++ C G + HC +
Sbjct: 2318 CNDGFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGWGPHCEI 2377
Query: 870 CLQGWTGPLCNLPLSSCQKAALSQGIDVSS------LCHNGGLCVDSGPSYFCHCPPGFQ 923
C + G + L + ++ G D+ +C NG CV+ SY C C G+
Sbjct: 2378 C--PFQGTVAFKKLCPHGRGFMTNGADIDECKVIHDVCRNGE-CVNDRGSYHCICKTGYT 2434
Query: 924 ----GSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGY----DGQNCSKELDACQSQ 975
G+ C D +N C P C Y C C GY DG++C K+LD C ++
Sbjct: 2435 PDITGTSCVD-LNECNQAPKPCNFICKNTEGSYQCSCPKGYILQEDGRSC-KDLDECATK 2492
Query: 976 PCHNHGTCTPKPGGFHCACPPGFVGLRCEG-DVDECLDQPCHPTGTAACHSLANAFYCQC 1034
+ C GGF C CPPGF D +EC C + +F C+C
Sbjct: 2493 QHNCQFLCVNTIGGFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQNTPGSFTCEC 2552
Query: 1035 LPG----HTGQWCEVEIDPCH-SQPCFHGGTCEATAGSPLGFICHCPKG----FEGPTCS 1085
G TG CE ++D C + C HG C+ G G+ C CP+G ++ C
Sbjct: 2553 QRGFSLDQTGSSCE-DVDECEGNHRCQHG--CQNIIG---GYRCSCPQGYLQHYQWNQCV 2606
Query: 1086 HRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGY------GGPDCLTPPAPKGCG-PPS 1138
H C GG + + +C C +G+ GG + CG +
Sbjct: 2607 DENECLSAHIC--GGASCHNTLGSY--KCMCPAGFQYEQFSGGCQDINE-----CGSAQA 2657
Query: 1139 PCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGN 1197
PC Y CS T G G+ C CP PG R G G C +G GN
Sbjct: 2658 PCSY--GCSNTEG----GYLCGCP---PG-----------YFRIGQGHCVSGMGMGRGN 2696
Score = 317 bits (812), Expect = 7e-86
Identities = 363/1319 (27%), Positives = 509/1319 (38%), Gaps = 326/1319 (24%)
Query: 35 CANGGTCLSLSLGQGTCQCAPGF---LGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLP 91
C NG C+ G C+C GF L C D C+ GG C
Sbjct: 460 CQNG-RCIPTP-GSCRCECNKGFQLDLRGECIDVDECEKNPCA--GGEC----------- 504
Query: 92 SSPSPLTPSFLCTCLPGF--TGERCQAKLEDPCPPS--FCSKRGRCHIQASGRPQCSCMP 147
S+ C C G+ T R + + D C + C+ GRC I G C C
Sbjct: 505 ---INNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNN-GRC-INTDGSFHCVCNA 559
Query: 148 GW----TGEQCQLRDFCSA-NPCVNGGVCLATYPQIQCHCPPGF----EGHACERDVNEC 198
G+ G+ C+ D CS N C+NG +C+ +C C PGF +G C +D+NEC
Sbjct: 560 GFHVTRDGKNCEDMDECSIRNMCLNG-MCINEDGSFKCICKPGFQLASDGRYC-KDINEC 617
Query: 199 FQDPGPCPKGTSCHNTLGSFQCLC----PVGQEGPRC-----------ELRAGPC--PPR 241
+ PG C G C NT GS++C C VG +G C + G C P
Sbjct: 618 -ETPGICMNG-RCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRSTCYGGYKRGQCIKPLF 675
Query: 242 G--------CSN-----GGTCQLMPEKDSTFHLCLCP--PGFIGP-----DCEVNPDNCV 281
G C++ G CQ P ++S + LC PG +C ++PD C
Sbjct: 676 GAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICP 735
Query: 282 SHQCQNGGTCQDGLDTYTCLCPETW----TGWDCSEDVDECETQGPPHCRNGGTCQNSAG 337
+ G C++ TY C+C + TG +C D++EC C N G C+N+ G
Sbjct: 736 N------GICENLRGTYKCICNSGYEVDSTGKNC-VDINEC-VLNSLLCDN-GQCRNTPG 786
Query: 338 SFHCVCVSGW----GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLC------PPGRTG 387
SF C C G+ +CE+ +D+C ++ C G C + GSF C C P +T
Sbjct: 787 SFVCTCPKGFIYKPDLKTCED-IDECESSPCING-VCKNSPGSFICECSSESTLDPTKTI 844
Query: 388 LLCHLEDMCLSQPCHGDAQCSTNPLT-------------GS--TLC----LCQPGYS--- 425
+ ++ C G + + N T GS TLC +C GYS
Sbjct: 845 CIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIK 904
Query: 426 GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY----TGSRC--------- 472
G C +D+DEC + P C++ G C+NT GSF C CP G TG C
Sbjct: 905 GTQC-EDIDEC---EVFPGVCKN-GLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCF 959
Query: 473 -EADHNEC---LSQPCHPGSTCLDLLA---TFHC-------------LCPPG-------- 504
+ EC ++ + C + A T C LCP G
Sbjct: 960 LRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEI 1019
Query: 505 LEGQLCEVETNECASAPCL-NHADCHDLLNGFQCICLPGF---SGTRCEEDIDECRSSPC 560
G+ + NEC P L H C + + F+C C GF S R DIDECR SP
Sbjct: 1020 TNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPD 1079
Query: 561 ANG-GQCQDQPGAFHCKCLPGFEG-----PRCQTEVDECLSDPCPV-GASCLDLPGAFFC 613
G GQC + PG F CKC G+E C ++DEC DP G C + G++ C
Sbjct: 1080 LCGRGQCVNTPGDFECKCDEGYESGFMMMKNCM-DIDECQRDPLLCRGGVCHNTEGSYRC 1138
Query: 614 LCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTC---HHG 670
CP G +PN+ I ++ + + LCP+G + C C +H
Sbjct: 1139 ECPPGHQ--------LSPNISACIDI--NECELSAHLCPNGRCVNLIGKYQCACNPGYHS 1188
Query: 671 HCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYT---GPTCS 727
R CV D+ EC GGC + C Y C+C G+
Sbjct: 1189 TPDRLFCV-DI----DECSIMNGGCET-------FCTNSEGSYECSCQPGFALMPDQRSC 1236
Query: 728 EEMTACHSGPCL-NGGSCNPSPGGYYCTCPPSHTGP----------QCQTSTDYCVSAPC 776
++ C P + +GG C PG Y C C +C + + C+S
Sbjct: 1237 TDIDECEDNPNICDGGQCTNIPGEYRCLCYDGFMASEDMKTCVDVNECDLNPNICLS--- 1293
Query: 777 FNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCAD--------SPCRNRATCQDSPQGP 828
GTC N G+F C C MG+ G K + C D C A C ++
Sbjct: 1294 ---GTCENTKGSFICHCDMGYSGK----KGKTGCTDINECEIGAHNCGKHAVCTNTAGSF 1346
Query: 829 RCLCPTGYTGGSCQ-TLMDLCAQ--KPCPRNSHCLQTGPSFHCLCLQGWTGP-LCNLPLS 884
+C C G+ G + T +D C+ C +++ C T S+ CLC +G+TG L
Sbjct: 1347 KCSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTDLD 1406
Query: 885 SCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF----QGSLCQDHVNPCESRPCQ 940
C + +LC N G C+++ Y C C GF G C+D ++ C
Sbjct: 1407 ECSENL--------NLCGN-GQCLNAPGGYRCECDMGFVPSADGKACED-IDECSLPNIC 1456
Query: 941 NGATCMAQPSGYLCQCAPGYD----GQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPP 996
TC P + C+C GY+ G NC+ +++ C G C PG + C CPP
Sbjct: 1457 VFGTCHNLPGLFRCECEIGYELDRSGGNCT-DVNECLDPTTCISGNCVNTPGSYICDCPP 1515
Query: 997 GF------VGLRCEGDVDECLD-QPCHPTGTAACHS-----LANAFYCQCLPGHTGQWCE 1044
F VG + LD +P G AC + ++ A C L G CE
Sbjct: 1516 DFELNPTRVGCVDTRSGNCYLDIRPRGDNGDTACSNEIGVGVSKASCCCSLGKAWGTPCE 1575
Query: 1045 V-----------------------------EIDPCHSQP-CFHGGTCEATAGSPLGFICH 1074
+ +ID C P GG C T GS F C
Sbjct: 1576 MCPAVNTSEYKILCPGGEGFRPNPITVILEDIDECQELPGLCQGGKCINTFGS---FQCR 1632
Query: 1075 CPKGF----EGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPP 1129
CP G+ + C + C G+C P C + G C+ PP
Sbjct: 1633 CPTGYYLNEDTRVCD------DVNECETPGICGPG---------TCYNTVGNYTCICPP 1676
Score = 285 bits (728), Expect = 4e-76
Identities = 354/1394 (25%), Positives = 495/1394 (35%), Gaps = 339/1394 (24%)
Query: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGF----LGETCQFPDPCQNAQLCQNGGSCQAL 83
C + P C GG C++ ++G C+C G + + C+ D C GG C
Sbjct: 250 CQAIPGLC-QGGNCIN-TVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGEC--- 304
Query: 84 LPAPLGLPSSPSPLTPSFLCTCLPGF----TGERCQAKLEDPCPPSFCSKRGRCHIQ--- 136
+ S+ C C PGF G RC C + + GRC Q
Sbjct: 305 -----------TNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTALTN--GRCSNQLPQ 351
Query: 137 ASGRPQCSCMPG--WTG------EQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEG 188
+ + QC C G W+ E C +R N + + + P+ PP G
Sbjct: 352 SITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEY----PPPPLG 407
Query: 189 HACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPR---------CELRAGPCP 239
+ P P G + L P +E PR C+L C
Sbjct: 408 -----PIPPVLPVPPGFPPGPQIPVPRPPVEYLYP-SREPPRVLPVNVTDYCQLVRYLCQ 461
Query: 240 PRGC-SNGGTCQLMPEKDSTFHLCLCPPGF---IGPDCEVNPDNCVSHQCQNGGTCQDGL 295
C G+C+ C C GF + +C ++ D C + C GG C +
Sbjct: 462 NGRCIPTPGSCR-----------CECNKGFQLDLRGEC-IDVDECEKNPCA-GGECINNQ 508
Query: 296 DTYTCLC----PETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGW---- 347
+YTC C T T +C D+DEC G N G C N+ GSFHCVC +G+
Sbjct: 509 GSYTCQCRAGYQSTLTRTEC-RDIDECLQNG--RICNNGRCINTDGSFHCVCNAGFHVTR 565
Query: 348 GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPG----------RTGLLCHLEDMCL 397
G +CE+ +D+C CI+ GSF C+C PG + C +C+
Sbjct: 566 DGKNCED-MDECSIRNMCLNGMCINEDGSFKCICKPGFQLASDGRYCKDINECETPGICM 624
Query: 398 SQPC---HGDAQCSTNP-----LTGSTLCL-------CQPGYSGPTCHQDL------DEC 436
+ C G +C P L G +C+ C GY C + L EC
Sbjct: 625 NGRCVNTDGSYRCECFPGLAVGLDG-RVCVDTHMRSTCYGGYKRGQCIKPLFGAVTKSEC 683
Query: 437 LMAQQGPSPCEHGGSCLNTP----GSFNCLCPPGYTGSRCEADHNECLSQP-CHPGSTCL 491
A + G C P + LC G + +D NEC P P C
Sbjct: 684 CCAS---TEYAFGEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGICE 740
Query: 492 DLLATFHCLCPPGLE----GQLCEVETNECASAPCL-NHADCHDLLNGFQCICLPGF--- 543
+L T+ C+C G E G+ C V+ NEC L ++ C + F C C GF
Sbjct: 741 NLRGTYKCICNSGYEVDSTGKNC-VDINECVLNSLLCDNGQCRNTPGSFVCTCPKGFIYK 799
Query: 544 SGTRCEEDIDECRSSPCANGGQCQDQPGAFHCK-------------CLPGFEGPRCQTEV 590
+ EDIDEC SSPC N G C++ PG+F C+ C+ +G QT +
Sbjct: 800 PDLKTCEDIDECESSPCIN-GVCKNSPGSFICECSSESTLDPTKTICIETIKGTCWQTVI 858
Query: 591 D--------------ECLS-------DPCPV---------------GASCLDLP------ 608
D +C S PC + G C D+
Sbjct: 859 DGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCEDIDECEVFP 918
Query: 609 ------------GAFFCLCPSGF----TGQLC---------------------------E 625
G+F C CPSG TG++C +
Sbjct: 919 GVCKNGLCVNTRGSFKCQCPSGMTLDATGRICLDIRLETCFLRYEDEECTLPIAGRHRMD 978
Query: 626 VPLCAPNLCQPKQICKD----QKDKANCLCPDGSPGCAPPE-----------DNC----- 665
C+ + C++ + LCP G PG A E + C
Sbjct: 979 ACCCSVGAAWGTEECEECPMRNTPEYEELCPRG-PGFATKEITNGKPFFKDINECKMIPS 1037
Query: 666 TCHHGHCQRS----SCVCDVGWTGPECE---AELGGCISAPCAHG-GTCYPQPSGYNCTC 717
C HG C+ + C CD G+ E ++ C +P G G C P + C C
Sbjct: 1038 LCTHGKCRNTIGSFKCRCDSGFALDSEERNCTDIDECRISPDLCGRGQCVNTPGDFECKC 1097
Query: 718 PTGYTG-----PTCSEEMTACHSGPCL-NGGSCNPSPGGYYCTCPPSH-TGPQCQTSTDY 770
GY C ++ C P L GG C+ + G Y C CPP H P D
Sbjct: 1098 DEGYESGFMMMKNCM-DIDECQRDPLLCRGGVCHNTEGSYRCECPPGHQLSPNISACIDI 1156
Query: 771 --C-VSAPCFNGGTCVNRPGTFSCLCAMGFQGPR----CEGKLRPSCADSPCRNRATCQD 823
C +SA G CVN G + C C G+ C S + C C +
Sbjct: 1157 NECELSAHLCPNGRCVNLIGKYQCACNPGYHSTPDRLFCVDIDECSIMNGGC--ETFCTN 1214
Query: 824 SPQGPRCLCPTGYT----GGSCQTLMDLCAQKP--CPRNSHCLQTGPSFHCLCLQGWTGP 877
S C C G+ SC T +D C P C C + CLC G+
Sbjct: 1215 SEGSYECSCQPGFALMPDQRSC-TDIDECEDNPNICD-GGQCTNIPGEYRCLCYDGFMAS 1272
Query: 878 LCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSL----CQDHVNP 933
+ L+ I +S C N + S+ CHC G+ G C D +N
Sbjct: 1273 EDMKTCVDVNECDLNPNICLSGTCEN------TKGSFICHCDMGYSGKKGKTGCTD-INE 1325
Query: 934 CE--SRPCQNGATCMAQPSGYLCQCAPGY--DGQNCSKELDACQ--SQPCHNHGTCTPKP 987
CE + C A C + C C+PG+ DG C+ +LD C + C H C
Sbjct: 1326 CEIGAHNCGKHAVCTNTAGSFKCSCSPGWIGDGIKCT-DLDECSNGTHMCSQHADCKNTM 1384
Query: 988 GGFHCACPPGFV--GLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQC----LPGHTGQ 1041
G + C C G+ G C D+DEC + + G C + + C+C +P G+
Sbjct: 1385 GSYRCLCKEGYTGDGFTCT-DLDEC-SENLNLCGNGQCLNAPGGYRCECDMGFVPSADGK 1442
Query: 1042 WCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFE----GPTCSHRAPSCGFHHCH 1097
CE +ID C GTC G F C C G+E G C+ C
Sbjct: 1443 ACE-DIDECSLPNICVFGTCHNLPGL---FRCECEIGYELDRSGGNCTDVNECLDPTTCI 1498
Query: 1098 HGGLCLPSP-------KPGF---PPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCS 1147
G C+ +P P F P R C+ G +C P+G + +CS
Sbjct: 1499 SGN-CVNTPGSYICDCPPDFELNPTRVGCVDTRSG-NCYLDIRPRGDNGDT------ACS 1550
Query: 1148 ETTGLGGPGFRCSC 1161
G+G C C
Sbjct: 1551 NEIGVGVSKASCCC 1564
Score = 257 bits (657), Expect = 7e-68
Identities = 343/1422 (24%), Positives = 487/1422 (34%), Gaps = 313/1422 (22%)
Query: 102 LCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCS 161
+CTC G C ++ C C G C C C G+ G C + C
Sbjct: 99 MCTCPSGQIAPSCGSRSIQHCNIR-CMNGGSC-----SDDHCLCQKGYIGTHCG-QPVCE 151
Query: 162 ANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTS---CHNTLGSF 218
+ C+NGG C+A +C C GF G CERD GPC S C L
Sbjct: 152 SG-CLNGGRCVAPN---RCACTYGFTGPQCERDYRT-----GPCFTVISNQMCQGQLSGI 202
Query: 219 QC---LCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEV 275
C LC C G + G C++ P + P G +V
Sbjct: 203 VCTKTLC---------------CATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDV 247
Query: 276 NPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCS---EDVDECETQGPPHCRNGGTC 332
+ + CQ GG C + + ++ C CP + S ED+DEC T P GG C
Sbjct: 248 DECQAIPGLCQ-GGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTI--PGICEGGEC 304
Query: 333 QNSAGSFHCVCVSGW----GGTSCEENLDDCIAATCAPGSTCIDR----VGSFSCLCPPG 384
N+ S+ C C G+ GT C + + T C ++ + C C G
Sbjct: 305 TNTVSSYFCKCPPGFYTSPDGTRCID-VRPGYCYTALTNGRCSNQLPQSITKMQCCCDAG 363
Query: 385 RT--------------------GLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGY 424
R LC + + +P + P PG
Sbjct: 364 RCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFPPGP 423
Query: 425 SGPTCHQDLDECLMAQQGPSP--------CE------HGGSCLNTPGSFNCLCPPGYT-- 468
P ++ +++ P C+ G C+ TPGS C C G+
Sbjct: 424 QIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQLD 483
Query: 469 -GSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVET---NECA-SAPCL 523
C D +EC PC G C++ ++ C C G + L E +EC +
Sbjct: 484 LRGEC-IDVDECEKNPC-AGGECINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRIC 541
Query: 524 NHADCHDLLNGFQCICLPGFSGTR----CEEDIDECRSSPCANGGQCQDQPGAFHCKCLP 579
N+ C + F C+C GF TR CE D+DEC G C ++ G+F C C P
Sbjct: 542 NNGRCINTDGSFHCVCNAGFHVTRDGKNCE-DMDECSIRNMCLNGMCINEDGSFKCICKP 600
Query: 580 GF----EGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLC----PSGFTGQLCEVPLCAP 631
GF +G C+ +++EC + + C++ G++ C C G G++C V
Sbjct: 601 GFQLASDGRYCK-DINECETPGICMNGRCVNTDGSYRCECFPGLAVGLDGRVC-VDTHMR 658
Query: 632 NLC----QPKQICK---DQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWT 684
+ C + Q K K+ C C P C + ++ C G T
Sbjct: 659 STCYGGYKRGQCIKPLFGAVTKSECCCASTEYAFGEPCQPCPAQNSAEYQALCSSGPGMT 718
Query: 685 GPECEAELGGCISAP-CAHGGTCYPQPSGYNCTCPTGY----TGPTCSEEMTACHSGPCL 739
+++ C P G C Y C C +GY TG C + +
Sbjct: 719 --SAGSDINECALDPDICPNGICENLRGTYKCICNSGYEVDSTGKNCVDINECVLNSLLC 776
Query: 740 NGGSCNPSPGGYYCTCPPSHT-GPQCQT--STDYCVSAPCFNGGTCVNRPGTFSC----- 791
+ G C +PG + CTCP P +T D C S+PC N G C N PG+F C
Sbjct: 777 DNGQCRNTPGSFVCTCPKGFIYKPDLKTCEDIDECESSPCIN-GVCKNSPGSFICECSSE 835
Query: 792 --------LCAMGFQGP--------RCE-----GKLRPSCAD-------SPCRNRATCQD 823
+C +G RCE L+ C SPC CQ
Sbjct: 836 STLDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPC---TLCQV 892
Query: 824 SPQGPRCLCPTGYT---GGSCQTLMDLCAQKP-CPRNSHCLQTGPSFHCLCLQGWT---- 875
P +C GY+ G C+ + D C P +N C+ T SF C C G T
Sbjct: 893 DP-----ICGKGYSRIKGTQCEDI-DECEVFPGVCKNGLCVNTRGSFKCQCPSGMTLDAT 946
Query: 876 -----------------GPLCNLPLS-------------------SCQKAALSQGIDVSS 899
C LP++ C++ + +
Sbjct: 947 GRICLDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEE 1006
Query: 900 LCHNG------------------------------GLCVDSGPSYFCHCPPGF----QGS 925
LC G G C ++ S+ C C GF +
Sbjct: 1007 LCPRGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEER 1066
Query: 926 LCQDHVNPCESRP--CQNGATCMAQPSGYLCQCAPGYDG-----QNCSKELDACQSQP-- 976
C D ++ C P C G C+ P + C+C GY+ +NC ++D CQ P
Sbjct: 1067 NCTD-IDECRISPDLCGRG-QCVNTPGDFECKCDEGYESGFMMMKNC-MDIDECQRDPLL 1123
Query: 977 CHNHGTCTPKPGGFHCACPPGF---VGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQ 1033
C G C G + C CPPG + D++EC + H C +L + C
Sbjct: 1124 CRG-GVCHNTEGSYRCECPPGHQLSPNISACIDINEC-ELSAHLCPNGRCVNLIGKYQCA 1181
Query: 1034 CLPGHTGQ----WCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGF----EGPTCS 1085
C PG+ +C V+ID C +GG S + C C GF + +C+
Sbjct: 1182 CNPGYHSTPDRLFC-VDIDEC---SIMNGGCETFCTNSEGSYECSCQPGFALMPDQRSCT 1237
Query: 1086 HRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGY-GGPDCLTPPAPKGCG-PPSPCLYN 1143
+ GG C P RC C G+ D T C P+ CL +
Sbjct: 1238 DIDECEDNPNICDGGQCTNIPG---EYRCLCYDGFMASEDMKTCVDVNECDLNPNICL-S 1293
Query: 1144 GSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGC----EGRSGDGAC--DAGCSGPGGN 1197
G+C T G F C C G K G GC E G C A C+ G+
Sbjct: 1294 GTCENTKG----SFICHCDMGYSG----KKGKTGCTDINECEIGAHNCGKHAVCTNTAGS 1345
Query: 1198 WDGGDCSLGVPDPWKGCPSHSRC----WLLFRDGQCHPQCDSEECLF------DGYDCET 1247
+ CS G C C + + C S CL DG+ C
Sbjct: 1346 FK-CSCSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRCLCKEGYTGDGFTCTD 1404
Query: 1248 PPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRPEDG 1289
C+ + C NG C C D G DG
Sbjct: 1405 LDECSENLN-LC----GNGQCLNAPGGYRCECDMGFVPSADG 1441
Score = 206 bits (524), Expect = 2e-52
Identities = 291/1150 (25%), Positives = 403/1150 (35%), Gaps = 265/1150 (23%)
Query: 260 HLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECE 319
++C CP G I P C + +C NGG+C D CLC + + G C + V CE
Sbjct: 98 NMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDD----HCLCQKGYIGTHCGQPV--CE 151
Query: 320 TQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSC 379
+ C NGG C C C G+ G CE + T C ++ C
Sbjct: 152 S----GCLNGGRC---VAPNRCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVC 204
Query: 380 ---LCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDEC 436
LC H +MC +QP N TG+ QD+DEC
Sbjct: 205 TKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGAC--------------QDVDEC 250
Query: 437 LMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY----TGSRCEADHNECLSQP--CHPGSTC 490
Q P C+ GG+C+NT GSF C CP G+ +CE D +EC + P C G C
Sbjct: 251 ---QAIPGLCQ-GGNCINTVGSFECKCPAGHKLNEVSQKCE-DIDECSTIPGICE-GGEC 304
Query: 491 LDLLATFHCLCPPGL----EGQLC-EVETNECASAPCLNHADCHDLL----NGFQCIC-- 539
+ ++++ C CPPG +G C +V C +A L + C + L QC C
Sbjct: 305 TNTVSSYFCKCPPGFYTSPDGTRCIDVRPGYCYTA--LTNGRCSNQLPQSITKMQCCCDA 362
Query: 540 ----------LPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFH-----CKCLPGF-EG 583
P R ED ++ S P G+ + P PGF G
Sbjct: 363 GRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFPPG 422
Query: 584 PRCQTE----------------VDECLSDPCPV------GASCLDLPGAFFCLCPSGF-- 619
P+ + ++D C + C+ PG+ C C GF
Sbjct: 423 PQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCECNKGFQL 482
Query: 620 --TGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPE-----DNC-----TC 667
G+ +V C N C + C + + C C G D C C
Sbjct: 483 DLRGECIDVDECEKNPCAGGE-CINNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRIC 541
Query: 668 HHGHCQRSS----CVCDVGW----TGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPT 719
++G C + CVC+ G+ G CE ++ C G C + + C C
Sbjct: 542 NNGRCINTDGSFHCVCNAGFHVTRDGKNCE-DMDECSIRNMCLNGMCINEDGSFKCICKP 600
Query: 720 GY----TGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTC-PPSHTGPQCQTSTDYCVSA 774
G+ G C + G C+N G C + G Y C C P G + D + +
Sbjct: 601 GFQLASDGRYCKDINECETPGICMN-GRCVNTDGSYRCECFPGLAVGLDGRVCVDTHMRS 659
Query: 775 PCFNG---GTCV----NRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQG 827
C+ G G C+ C CA E C P +N A Q
Sbjct: 660 TCYGGYKRGQCIKPLFGAVTKSECCCA------STEYAFGEPCQPCPAQNSAEYQ----- 708
Query: 828 PRCLCPTGYTGGSCQTLMDLCAQKP--CPRNSHCLQTGPSFHCLCLQGW----TGPLCNL 881
LC +G S + ++ CA P CP N C ++ C+C G+ TG C +
Sbjct: 709 --ALCSSGPGMTSAGSDINECALDPDICP-NGICENLRGTYKCICNSGYEVDSTGKNC-V 764
Query: 882 PLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF----QGSLCQDHVNPCESR 937
++ C +L LC N G C ++ S+ C CP GF C+D ++ CES
Sbjct: 765 DINECVLNSL--------LCDN-GQCRNTPGSFVCTCPKGFIYKPDLKTCED-IDECESS 814
Query: 938 PCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPG 997
PC NG C P ++C+C + LD ++ C G C
Sbjct: 815 PCING-VCKNSPGSFICEC-------SSESTLDPTKT-------ICIETIKG---TCWQT 856
Query: 998 FVGLRCEGDVD-ECLDQPCHPTGTAACHSLANAF-----YCQ----CLPGHT---GQWCE 1044
+ RCE +++ L C C SL A+ CQ C G++ G CE
Sbjct: 857 VIDGRCEININGATLKSQC-------CSSLGAAWGSPCTLCQVDPICGKGYSRIKGTQCE 909
Query: 1045 VEIDPCHSQP-CFHGGTCEATAGSPLGFICHCPKGF----EGPTCSHRAPSCGFHHCHHG 1099
+ID C P G C T GS F C CP G G C F
Sbjct: 910 -DIDECEVFPGVCKNGLCVNTRGS---FKCQCPSGMTLDATGRICLDIRLETCFLRYEDE 965
Query: 1100 GLCLPSPKPGFPPRCACLSG--YGGPDCLTPP----------APKGCG------------ 1135
LP C C G +G +C P P+G G
Sbjct: 966 ECTLPIAGRHRMDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPF 1025
Query: 1136 ---------PPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGA 1186
PS C + G C T G F+C C ++ E R
Sbjct: 1026 FKDINECKMIPSLCTH-GKCRNTIG----SFKCRCDSGFALDSEERNCTDIDECRISPDL 1080
Query: 1187 CDAG-CSGPGGNWDGGDCSLGVPDPW---KGCPSHSRCW---LLFRDGQCHPQCDSEECL 1239
C G C G+++ C G + K C C LL R G CH S
Sbjct: 1081 CGRGQCVNTPGDFE-CKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGS---- 1135
Query: 1240 FDGYDCETPP 1249
Y CE PP
Sbjct: 1136 ---YRCECPP 1142
Score = 157 bits (397), Expect = 1e-37
Identities = 205/776 (26%), Positives = 283/776 (36%), Gaps = 164/776 (21%)
Query: 439 AQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFH 498
A +GP+ C GS +N C PG+ + N+C+ C +C D +
Sbjct: 52 ALKGPNVC---GS------RYNAYCCPGW---KTLPGGNQCIVPICR--HSCGDGFCSRP 97
Query: 499 --CLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECR 556
C CP G C + + + C+N C D C+C G+ GT C + + E
Sbjct: 98 NMCTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSD----DHCLCQKGYIGTHCGQPVCE-- 151
Query: 557 SSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCP 616
S C NGG+C C C GF GP+C+ + + PC S +C
Sbjct: 152 -SGCLNGGRCV---APNRCACTYGFTGPQCERDYR---TGPCFTVISNQ--------MCQ 196
Query: 617 SGFTGQLCEVPLCAPNLCQ----PKQICKDQKDKANC-LCPDGSPGCAPPEDNCTCHHGH 671
+G +C LC + + P ++C Q P+ G D C G
Sbjct: 197 GQLSGIVCTKTLCCATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGL 256
Query: 672 CQRSSCVCDVGWTGPECEA------------ELGGCISAP-CAHGGTCYPQPSGYNCTCP 718
CQ +C+ VG +C A ++ C + P GG C S Y C CP
Sbjct: 257 CQGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCP 316
Query: 719 TG-YTGP--TCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAP 775
G YT P T ++ + L G C+ P S T QC C +
Sbjct: 317 PGFYTSPDGTRCIDVRPGYCYTALTNGRCSNQ-------LPQSITKMQC-----CCDAGR 364
Query: 776 CFNGGTCV-------NRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGP 828
C++ G V F+ LC++ P RP P P P
Sbjct: 365 CWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPG-----RPEYPPPPL--------GPIPP 411
Query: 829 RCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQK 888
P G+ G Q P PR P L P LP++
Sbjct: 412 VLPVPPGFPPG---------PQIPVPR--------PPVEYLYPS--REPPRVLPVNVTDY 452
Query: 889 AALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSL---CQDHVNPCESRPCQNGATC 945
L V LC N G C+ + S C C GFQ L C D V+ CE PC G C
Sbjct: 453 CQL-----VRYLCQN-GRCIPTPGSCRCECNKGFQLDLRGECID-VDECEKNPCA-GGEC 504
Query: 946 MAQPSGYLCQCAPGYDG---QNCSKELDAC-QSQPCHNHGTCTPKPGGFHCACPPGF--- 998
+ Y CQC GY + +++D C Q+ N+G C G FHC C GF
Sbjct: 505 INNQGSYTCQCRAGYQSTLTRTECRDIDECLQNGRICNNGRCINTDGSFHCVCNAGFHVT 564
Query: 999 -VGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPG----HTGQWCEVEIDPCHSQ 1053
G CE D+DEC + G C + +F C C PG G++C+ +I+ C +
Sbjct: 565 RDGKNCE-DMDECSIRNMCLNG--MCINEDGSFKCICKPGFQLASDGRYCK-DINECETP 620
Query: 1054 PCFHGGTCEATAGSPLGFICHC----PKGFEGPTC--SHRAPSCGFHHCHHGGLCLPSPK 1107
G C T GS + C C G +G C +H +C + + G C+ K
Sbjct: 621 GICMNGRCVNTDGS---YRCECFPGLAVGLDGRVCVDTHMRSTC--YGGYKRGQCI---K 672
Query: 1108 PGF----PPRCACLS---GYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPG 1156
P F C C S +G P C PA Y CS G+ G
Sbjct: 673 PLFGAVTKSECCCASTEYAFGEP-CQPCPAQNSAE------YQALCSSGPGMTSAG 721
Score = 94.7 bits (234), Expect = 8e-19
Identities = 84/282 (29%), Positives = 108/282 (38%), Gaps = 68/282 (24%)
Query: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFL----GETCQFPDPCQNAQLCQNGGSCQAL 83
C P+PC C + G C C G++ G +C+ D C Q +CQ L
Sbjct: 2448 CNQAPKPC--NFICKNTE-GSYQCSCPKGYILQEDGRSCKDLDECATKQ-----HNCQFL 2499
Query: 84 LPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPP--SFCSKRGRCHIQASGRP 141
+G F C C PGFT + C + C +G C G
Sbjct: 2500 CVNTIG----------GFTCKCPPGFTQHHTSCIDNNECTSDINLCGSKGICQ-NTPGSF 2548
Query: 142 QCSCMPGW----TGEQCQLRDFCSANP-CVNGGVCLATYPQIQCHCPPGFEGH----ACE 192
C C G+ TG C+ D C N C +G C +C CP G+ H C
Sbjct: 2549 TCECQRGFSLDQTGSSCEDVDECEGNHRCQHG--CQNIIGGYRCSCPQGYLQHYQWNQCV 2606
Query: 193 RDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG----------QEGPRCELRAGPCPPRG 242
D NEC G SCHNTLGS++C+CP G Q+ C PC G
Sbjct: 2607 -DENECLS--AHICGGASCHNTLGSYKCMCPAGFQYEQFSGGCQDINECGSAQAPC-SYG 2662
Query: 243 CSN--GGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVS 282
CSN GG +LC CPPG+ + +CVS
Sbjct: 2663 CSNTEGG------------YLCGCPPGYF----RIGQGHCVS 2688
Score = 89.0 bits (219), Expect = 4e-17
Identities = 89/306 (29%), Positives = 120/306 (39%), Gaps = 77/306 (25%)
Query: 35 CANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSP 94
C NGG+C C C G++G C P C++ C NGG C A P+
Sbjct: 123 CMNGGSC-----SDDHCLCQKGYIGTHCGQP-VCESG--CLNGGRCVA--------PNR- 165
Query: 95 SPLTPSFLCTCLPGFTGERCQAKLED-PCPPSFCSKRGRCHIQASG----RPQCSCMPG- 148
C C GFTG +C+ PC ++ C Q SG + C G
Sbjct: 166 --------CACTYGFTGPQCERDYRTGPCFTVISNQM--CQGQLSGIVCTKTLCCATVGR 215
Query: 149 -WTGEQCQLRDFCSA--NPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPC 205
W G C++ C A +PC G + P AC+ DV+EC PG C
Sbjct: 216 AW-GHPCEM---CPAQPHPCRRGFI-------------PNIRTGACQ-DVDECQAIPGLC 257
Query: 206 PKGTSCHNTLGSFQCLCPVGQE----GPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHL 261
+G +C NT+GSF+C CP G + +CE G GG C + +
Sbjct: 258 -QGGNCINTVGSFECKCPAGHKLNEVSQKCEDIDECSTIPGICEGGEC----TNTVSSYF 312
Query: 262 CLCPPGF-IGPD----CEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVD 316
C CPPGF PD +V P C + G C + L P++ T C D
Sbjct: 313 CKCPPGFYTSPDGTRCIDVRPGYC--YTALTNGRCSNQL-------PQSITKMQCCCDAG 363
Query: 317 ECETQG 322
C + G
Sbjct: 364 RCWSPG 369
Score = 66.2 bits (160), Expect = 3e-10
Identities = 93/356 (26%), Positives = 121/356 (33%), Gaps = 90/356 (25%)
Query: 863 GPSFHCLCLQGWT----GPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHC 918
G ++ C GW G C +P+ C+ + G C S P+ C C
Sbjct: 60 GSRYNAYCCPGWKTLPGGNQCIVPI--CRHSC------------GDGFC--SRPN-MCTC 102
Query: 919 PPGFQGSLCQDH-VNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPC 977
P G C + C R C NG +C S C C GY G +C + + C+S C
Sbjct: 103 PSGQIAPSCGSRSIQHCNIR-CMNGGSC----SDDHCLCQKGYIGTHCGQPV--CESG-C 154
Query: 978 HNHGTCTPKPGGFHCACPPGFVGLRCEGD--VDECL----DQPCHP-------TGTAACH 1024
N G C CAC GF G +CE D C +Q C T T C
Sbjct: 155 LNGGRCVAPN---RCACTYGFTGPQCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCCA 211
Query: 1025 SLANAFYCQC--------------LPGHTGQWCEVEIDPCHSQP-CFHGGTCEATAGSPL 1069
++ A+ C +P C+ ++D C + P GG C T GS
Sbjct: 212 TVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQ-DVDECQAIPGLCQGGNCINTVGS-- 268
Query: 1070 GFICHCPKGFEGPTCSHRAPSCGFHHCH------HGGLCLPSPKPGFPPRCACLSGYGGP 1123
F C CP G + S + C GG C + F C C G+
Sbjct: 269 -FECKCPAGHKLNEVSQKCED--IDECSTIPGICEGGECTNTVSSYF---CKCPPGF--- 319
Query: 1124 DCLTPPAPKGCGPPSP-----CLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPG 1174
T P C P L NG CS +C C RC PG
Sbjct: 320 --YTSPDGTRCIDVRPGYCYTALTNGRCSNQLPQSITKMQCCC----DAGRCWSPG 369
Score = 56.6 bits (135), Expect = 2e-07
Identities = 82/356 (23%), Positives = 104/356 (29%), Gaps = 101/356 (28%)
Query: 1019 GTAACHSLANAFYC---QCLPGHTGQWCEVEIDPCHSQPCFHG---GTCEATAGSPLGFI 1072
G C S NA+ C + LPG G C V I C H G C +
Sbjct: 55 GPNVCGSRYNAYCCPGWKTLPG--GNQCIVPI-------CRHSCGDGFCSRPN------M 99
Query: 1073 CHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPK 1132
C CP G P+C R+ C +GG C C C GY G C P
Sbjct: 100 CTCPSGQIAPSCGSRSIQHCNIRCMNGGSCSDD-------HCLCQKGYIGTHCGQPVCES 152
Query: 1133 GCGPPSPCLYNGSCSETTGLGGPGFRCS----------------CPHSSPGPRCQK---- 1172
GC C+ C+ T G GP +C C G C K
Sbjct: 153 GCLNGGRCVAPNRCACTYGFTGP--QCERDYRTGPCFTVISNQMCQGQLSGIVCTKTLCC 210
Query: 1173 -------------------PGAKGCEGRSGDGACD--AGCSGPGGNWDGGDCSLGVPDPW 1211
P +G GAC C G GG+C V
Sbjct: 211 ATVGRAWGHPCEMCPAQPHPCRRGFIPNIRTGACQDVDECQAIPGLCQGGNCINTVGSFE 270
Query: 1212 KGCPS-------HSRCWLLFRDGQCHPQCDSEEC--LFDGYDCETPPA---------CTP 1253
CP+ +C + C+ EC Y C+ PP C
Sbjct: 271 CKCPAGHKLNEVSQKCEDIDECSTIPGICEGGECTNTVSSYFCKCPPGFYTSPDGTRCID 330
Query: 1254 AYDQYCHDHFHNGHCE----KGCNTAECGWDGGDCRPEDGDPEWGPSLALLVVLSP 1305
YC+ NG C + +C D G C W P + + + P
Sbjct: 331 VRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRC--------WSPGVTVAPEMCP 378
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 327 bits (837), Expect = 9e-89
Identities = 394/1452 (27%), Positives = 559/1452 (38%), Gaps = 333/1452 (22%)
Query: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGE--TCQFPDPC-QNAQLCQNGGSCQALL 84
C + C+ C++ G C C+ GF G+ TC D C +N LC+NG C
Sbjct: 1412 CSNGTHQCSINAQCVNTP-GSYRCACSEGFTGDGFTCSDVDECAENINLCENG-QC---- 1465
Query: 85 PAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCS--KRGRCHIQASGRPQ 142
L +P + + C C GFT +D SF + G C+ G
Sbjct: 1466 ---LNVPGA-------YRCECEMGFTPASDSRSCQDIDECSFQNICVFGTCN-NLPGMFH 1514
Query: 143 CSCMPGW----TGEQCQLRDFCSANP--CVNGGVCLATYPQIQCHCPPGFE----GHAC- 191
C C G+ TG C D C A+P CVNG +C+ T + +C+CPP F+ G C
Sbjct: 1515 CICDDGYELDRTGGNCTDIDEC-ADPINCVNG-LCVNTPGRYECNCPPDFQLNPTGVGCV 1572
Query: 192 ERDVNECFQDPGPCPKGT-SCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQ 250
+ V C+ GP G+ SC+ +G VG C C G + G C+
Sbjct: 1573 DNRVGNCYLKFGPRGDGSLSCNTEIG-------VGVSRSSC------CCSLGKAWGNPCE 1619
Query: 251 LMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSH---QCQ------NGGTCQDGLDTYTCL 301
P +ST + LCP G NP + +CQ GG C + ++ C
Sbjct: 1620 TCPPVNSTEYYTLCPG---GEGFRPNPITIILEDIDECQELPGLCQGGNCINTFGSFQCE 1676
Query: 302 CPETW---TGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVC------VSG------ 346
CP+ + ED+DEC P GTC N+ G++ C+C V+G
Sbjct: 1677 CPQGYYLSEDTRICEDIDECFAH--PGVCGPGTCYNTLGNYTCICPPEYMQVNGGHNCMD 1734
Query: 347 ---------WGGTSCEENLDDCIAATCAPGSTCIDRVG-SFSCLCPPGRTGLLCHLEDMC 396
+ GT+CE L + C VG +++ C P T + +C
Sbjct: 1735 MRKSFCYRSYNGTTCENELPFNVTKRMC---CCTYNVGKAWNKPCEPCPTPGTADFKTIC 1791
Query: 397 LSQPCH------GDA----QCSTNP----------LTGSTLCLCQPGYSGP----TCHQD 432
+ P G A +C P GS C C G+S C +D
Sbjct: 1792 GNIPGFTFDIHTGKAVDIDECKEIPGICANGVCINQIGSFRCECPTGFSYNDLLLVC-ED 1850
Query: 433 LDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEA--DHNECLSQP--CHPGS 488
+DEC G + C+ C+N+PGS+ C C G+ S A D NECL P C G
Sbjct: 1851 IDEC---SNGDNLCQRNADCINSPGSYRCECAAGFKLSPNGACVDRNECLEIPNVCSHG- 1906
Query: 489 TCLDLLATFHCLCPPGL---EGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSG 545
C+DL ++ C+C G + Q ++ +EC PC N C + + + C+C PGF
Sbjct: 1907 LCVDLQGSYQCICHNGFKASQDQTMCMDVDECERHPCGN-GTCKNTVGSYNCLCYPGFEL 1965
Query: 546 TRCEE--DIDECRS---SPCANGGQCQDQPGAFHCKCLPGFE----GPRCQTEVDECLSD 596
T + DIDEC S C N G+C ++ G+F C C G+E G C + +EC++
Sbjct: 1966 THNNDCLDIDECSSFFGQVCRN-GRCFNEIGSFKCLCNEGYELTPDGKNC-IDTNECVAL 2023
Query: 597 P--CPVGASCLDLPGAFFCLCPSGF---TGQLCEVPLC--APNLCQPKQICKDQKDKANC 649
P C G +C +L G+F C+CP G+ + ++ C PN+C C + C
Sbjct: 2024 PGSCSPG-TCQNLEGSFRCICPPGYEVKSENCIDINECDEDPNICLFGS-CTNTPGGFQC 2081
Query: 650 LCPDGSPGCAPPEDNCTC------------HHGHCQ--------RSSCVCD----VGWTG 685
LCP PG ++ C +G C ++ C C GW G
Sbjct: 2082 LCP---PGFVLSDNGRRCFDTRQSFCFTNFENGKCSVPKAFNTTKAKCCCSKMPGEGW-G 2137
Query: 686 PECEA-----ELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLN 740
CE E+ P HG PS ++ T C E C +G C+N
Sbjct: 2138 DPCELCPKDDEVAFQDLCPYGHGTV----PSLHD----TREDVNECLESPGICSNGQCIN 2189
Query: 741 GGSCNPSPGGYYCTCPP----SHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMG 796
+ G + C CP +TG +C + + + PC N GTC N G+F C C G
Sbjct: 2190 ------TDGSFRCECPMGYNLDYTGVRCVDTDECSIGNPCGN-GTCTNVIGSFECNCNEG 2242
Query: 797 FQ-GPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTL---MDLCAQ-- 850
F+ GP + CA +P C ++ C CP GY Q + +D CA+
Sbjct: 2243 FEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGL 2302
Query: 851 KPC-PRNSHCLQTGPSFHCLCLQGWT----GPLCNLPLSSCQKAALSQGIDVSSLCHNGG 905
C R C +F C+C G G C + + C+ +C N G
Sbjct: 2303 HDCESRGMMCKNLIGTFMCICPPGMARRPDGEGC-VDENECRTK--------PGICEN-G 2352
Query: 906 LCVDSGPSYFCHCPPGFQ----GSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYD 961
CV+ SY C C GFQ G+ C D+ C A+ +CQ A
Sbjct: 2353 RCVNIIGSYRCECNEGFQSSSSGTECLDN----------RQGLCFAEVLQTICQMAS--S 2400
Query: 962 GQNCSKELDAC---------QSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEG-DVDECL 1011
+N + + C Q + C GT K CP G G +G D+DEC
Sbjct: 2401 SRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKK-----ICPHG-PGYTTDGRDIDECK 2454
Query: 1012 DQPCHPTGTAACHSLANAFYCQCLPGHT----GQWCEVEIDPCHSQPCFHGGTCEATAGS 1067
P T C + +F C C G+T G C +++D C P C+ T GS
Sbjct: 2455 VMPNLCT-NGQCINTMGSFRCFCKVGYTTDISGTSC-IDLDECSQSPKPCNYICKNTEGS 2512
Query: 1068 PLGFICHCPKGF----EGPTCSHRAPSCGF--HHCHHGGLCLPSPKPGFPPRCACLSGYG 1121
+ C CP+G+ +G TC C H+C + C++ G
Sbjct: 2513 ---YQCSCPRGYVLQEDGKTCKD-LDECQTKQHNC----------------QFLCVNTLG 2552
Query: 1122 GPDCLTPPA----------PKGCG-PPSPCLYNGSCSETTGLGGPGFRCSCPH----SSP 1166
G C PP CG PS C G C T G F C C +
Sbjct: 2553 GFTCKCPPGFTQHHTACIDNNECGSQPSLCGAKGICQNTPG----SFSCECQRGFSLDAT 2608
Query: 1167 GPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPD--PWKGCPSHSRCWLLF 1224
G C+ C+ G+ C GC G + G C G W C + C
Sbjct: 2609 GLNCE--DVDECD---GNHRCQHGCQNILGGYRCG-CPQGYIQHYQWNQCVDENEC---- 2658
Query: 1225 RDGQCHPQ-CDSEEC--LFDGYDCETPPACTPAYDQY---CHD----HFHNGHCEKGCNT 1274
+P C S C Y C P ++DQ+ CHD C GC+
Sbjct: 2659 ----SNPNACGSASCYNTLGSYKCACPSGF--SFDQFSSACHDVNECSSSKNPCNYGCSN 2712
Query: 1275 AECGWDGGDCRP 1286
E G+ G C P
Sbjct: 2713 TEGGYLCG-CPP 2723
Score = 315 bits (807), Expect = 3e-85
Identities = 364/1393 (26%), Positives = 535/1393 (38%), Gaps = 351/1393 (25%)
Query: 27 LCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGET---CQFPDPCQNAQLCQNGGSCQAL 83
+C C NG C+ ++ C+C G+ + C D C + C NG
Sbjct: 497 ICKHHANLCLNG-RCIP-TVSSYRCECNMGYKQDANGDCIDVDEC-TSNPCTNGDCVN-- 551
Query: 84 LPAPLGLPSSPSPLTP-SFLCTCLPGF----TGERCQAKLEDPCPPSFCSKRGRCHIQAS 138
TP S+ C C GF T + C +++ K GRC +
Sbjct: 552 --------------TPGSYYCKCHAGFQRTPTKQAC-IDIDECIQNGVLCKNGRC-VNTD 595
Query: 139 GRPQCSCMPGWT----GEQCQLRDFCSA-NPCVNGGVCLATYPQIQCHCPPGF----EGH 189
G QC C G+ G+ C D C+ N C+NG +C+ +C C PGF G
Sbjct: 596 GSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNG-MCINEDGSFKCICKPGFVLAPNGR 654
Query: 190 ACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCP----VGQEGPRC-----------ELR 234
C DV+EC Q PG C G C N+ GSF+C CP VG +G C ++
Sbjct: 655 YC-TDVDEC-QTPGICMNG-HCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIK 711
Query: 235 AGPC--PPRG--------CSN-----GGTCQLMPEKDSTFHLCLCPPGFIG--------P 271
G C P G C+N G CQ P K+S LC G +G
Sbjct: 712 KGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSG-VGITVDGRDIN 770
Query: 272 DCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETW----TGWDCSEDVDECETQGPPHCR 327
+C ++PD C + G C++ +Y C C + +G +C D+DEC C
Sbjct: 771 ECALDPDICAN------GICENLRGSYRCNCNSGYEPDASGRNCI-DIDEC-LVNRLLCD 822
Query: 328 NGGTCQNSAGSFHCVCVSGW---GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPG 384
N G C+N+ GS+ C C G+ T E++++C + C G+ C + +GSF+C C PG
Sbjct: 823 N-GLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGA-CRNNLGSFNCECSPG 880
Query: 385 ----RTGLLC--HLEDMCLSQPCHGDAQCSTNPLTGSTL--------------------- 417
TGL+C L+ C D++C N + G+TL
Sbjct: 881 SKLSSTGLICIDSLKGTCWLN--IQDSRCEVN-INGATLKSECCATLGAAWGSPCERCEL 937
Query: 418 -CLCQPGYS---GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY----TG 469
C G + G TC +D++EC + P C + G C+N+ GSF+C CP G TG
Sbjct: 938 DTACPRGLARIKGVTC-EDVNEC---EVFPGVCPN-GRCVNSKGSFHCECPEGLTLDGTG 992
Query: 470 SRC----------EADHNECLSQPCHP------------------GSTCLDL----LATF 497
C + D +EC+ HP G+ C + +
Sbjct: 993 RVCLDIRMEQCYLKWDEDECI----HPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEY 1048
Query: 498 HCLCPPG---------LEGQLCEVETNECASAPCL-NHADCHDLLNGFQCICLPGFSGTR 547
LCP G L G+ + NEC + P + + C + + F+C C GF+
Sbjct: 1049 ETLCPRGAGFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDM 1108
Query: 548 CEE---DIDECRSSP-CANGGQCQDQPGAFHCKCLPGFEG-----PRCQTEVDECLSDPC 598
E DIDECR SP G C + PG+F C+C G+E C ++DEC +P
Sbjct: 1109 EERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCM-DIDECERNPL 1167
Query: 599 PV-GASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKD--QKDKANCLCPDGS 655
G +C++ G+F C CP G L ++ C D + ++ LC +G
Sbjct: 1168 LCRGGTCVNTEGSFQCDCPLGH------------ELSPSREDCVDINECSLSDNLCRNGK 1215
Query: 656 PGCAPPEDNCTCHHGH---CQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSG 712
C+C+ G+ R C D+ EC GGC + C
Sbjct: 1216 CVNMIGTYQCSCNPGYQATPDRQGCT-DI----DECMIMNGGCDT-------QCTNSEGS 1263
Query: 713 YNCTCPTGYT----GPTCSEEMTACHSGPCL-NGGSCNPSPGGYYCTCPPSHTGP----- 762
Y C+C GY G +C+ ++ C + P + +GG C PG Y C C
Sbjct: 1264 YECSCSEGYALMPDGRSCA-DIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDMKT 1322
Query: 763 -----QCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPR----CEGKLRPSCADS 813
+C +++ C+ G C N G+F C C +G+ + C
Sbjct: 1323 CIDVNECDLNSNICMF------GECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAH 1376
Query: 814 PCRNRATCQDSPQGPRCLCPTGYTGGSCQTL-MDLCAQ--KPCPRNSHCLQTGPSFHCLC 870
C A+C + P +C C G+ G + + +D C+ C N+ C+ T S+ C C
Sbjct: 1377 NCDMHASCLNIPGSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCAC 1436
Query: 871 LQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGF----QGSL 926
+G+TG S + A + +LC N G C++ +Y C C GF
Sbjct: 1437 SEGFTGD--GFTCSDVDECA-----ENINLCEN-GQCLNVPGAYRCECEMGFTPASDSRS 1488
Query: 927 CQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYD----GQNCSKELDACQSQPCHNHGT 982
CQD ++ C + TC P + C C GY+ G NC+ ++D C +G
Sbjct: 1489 CQD-IDECSFQNICVFGTCNNLPGMFHCICDDGYELDRTGGNCT-DIDECADPINCVNGL 1546
Query: 983 CTPKPGGFHCACPPGF----VGLRC-EGDVDEC-LDQPCHPTGTAACHS-----LANAFY 1031
C PG + C CPP F G+ C + V C L G+ +C++ ++ +
Sbjct: 1547 CVNTPGRYECNCPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGVGVSRSSC 1606
Query: 1032 CQCLPGHTGQWCEV-----------------------------EIDPCHSQP-CFHGGTC 1061
C L G CE +ID C P GG C
Sbjct: 1607 CCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPGLCQGGNC 1666
Query: 1062 EATAGSPLGFICHCPKGF---EGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLS 1118
T GS F C CP+G+ E C H G+C P C +
Sbjct: 1667 INTFGS---FQCECPQGYYLSEDTRICEDIDEC----FAHPGVCGPG---------TCYN 1710
Query: 1119 GYGGPDCLTPPAPKGCGPPSPCL----------YNG-SCSETTGLGGPGFRCSCPH---- 1163
G C+ PP C+ YNG +C C C +
Sbjct: 1711 TLGNYTCICPPEYMQVNGGHNCMDMRKSFCYRSYNGTTCENELPFNVTKRMCCCTYNVGK 1770
Query: 1164 --SSPGPRCQKPG 1174
+ P C PG
Sbjct: 1771 AWNKPCEPCPTPG 1783
Score = 294 bits (752), Expect = 7e-79
Identities = 318/1155 (27%), Positives = 450/1155 (38%), Gaps = 269/1155 (23%)
Query: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFL----GETCQFPDPCQNAQLCQ---NGGSC 80
C + P C G TC + +LG TC C P ++ G C C NG +C
Sbjct: 1696 CFAHPGVCGPG-TCYN-TLGNYTCICPPEYMQVNGGHNCMD----MRKSFCYRSYNGTTC 1749
Query: 81 QALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGR 140
+ LP + +C C + + K +PCP A +
Sbjct: 1750 ENELPFNV----------TKRMCCCT--YNVGKAWNKPCEPCPTPGT---------ADFK 1788
Query: 141 PQCSCMPGWT-----GEQCQLRDFCSANP--CVNGGVCLATYPQIQCHCPPGFEGH---- 189
C +PG+T G+ + D C P C NG VC+ +C CP GF +
Sbjct: 1789 TICGNIPGFTFDIHTGKAVDI-DECKEIPGICANG-VCINQIGSFRCECPTGFSYNDLLL 1846
Query: 190 ACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTC 249
CE D++EC C + C N+ GS++C C G + P C + C
Sbjct: 1847 VCE-DIDECSNGDNLCQRNADCINSPGSYRCECAAGFK---------LSPNGACVDRNEC 1896
Query: 250 QLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGW 309
+P N SH G C D +Y C+C G+
Sbjct: 1897 LEIP-------------------------NVCSH-----GLCVDLQGSYQCICHN---GF 1923
Query: 310 DCSED------VDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEE--NLDDC-- 359
S+D VDECE H GTC+N+ GS++C+C G+ T + ++D+C
Sbjct: 1924 KASQDQTMCMDVDECER----HPCGNGTCKNTVGSYNCLCYPGFELTHNNDCLDIDECSS 1979
Query: 360 -IAATCAPGSTCIDRVGSFSCLCPPGRT----GLLCHLEDMCLSQPCHGDAQCSTNP--- 411
C G C + +GSF CLC G G C + C++ P CS
Sbjct: 1980 FFGQVCRNGR-CFNEIGSFKCLCNEGYELTPDGKNCIDTNECVALP----GSCSPGTCQN 2034
Query: 412 LTGSTLCLCQPGYS--GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY-- 467
L GS C+C PGY C D++EC + P+ C G SC NTPG F CLCPPG+
Sbjct: 2035 LEGSFRCICPPGYEVKSENCI-DINEC---DEDPNICLFG-SCTNTPGGFQCLCPPGFVL 2089
Query: 468 --TGSRC----------EADHNECLSQP-----------CHP------GSTC----LDLL 494
G RC ++ +C S P C G C D
Sbjct: 2090 SDNGRRCFDTRQSFCFTNFENGKC-SVPKAFNTTKAKCCCSKMPGEGWGDPCELCPKDDE 2148
Query: 495 ATFHCLCPPGLEGQLCEV-----ETNECASAPCL-NHADCHDLLNGFQCICLPG----FS 544
F LCP G G + + + NEC +P + ++ C + F+C C G ++
Sbjct: 2149 VAFQDLCPYG-HGTVPSLHDTREDVNECLESPGICSNGQCINTDGSFRCECPMGYNLDYT 2207
Query: 545 GTRCEEDIDECR-SSPCANGGQCQDQPGAFHCKCLPGFE-GPRCQTE-VDECLSDPCPVG 601
G RC D DEC +PC N G C + G+F C C GFE GP E ++EC +P
Sbjct: 2208 GVRC-VDTDECSIGNPCGN-GTCTNVIGSFECNCNEGFEPGPMMNCEDINECAQNPLLCA 2265
Query: 602 ASCLDLPGAFFCLCPSGFT----GQLC-EVPLCAPNL--CQPK-QICKDQKDKANCLCPD 653
C++ G++ C CP G+ ++C ++ CA L C+ + +CK+ C+CP
Sbjct: 2266 FRCMNTFGSYECTCPIGYALREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMCICPP 2325
Query: 654 G------SPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPEC-EAELGGCISAPCAHG--G 704
G GC E+ C G C+ CV +G EC E C G
Sbjct: 2326 GMARRPDGEGCV-DENECRTKPGICENGRCVNIIGSYRCECNEGFQSSSSGTECLDNRQG 2384
Query: 705 TCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCN--PSPG--GYYCTCP--PS 758
C+ + C + + C G G C P PG Y CP P
Sbjct: 2385 LCFAEV--LQTICQMASSSRNLVTKSECCCDGGRGWGHQCELCPLPGTAQYKKICPHGPG 2442
Query: 759 HTG-----PQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGF----QGPRCEGKLRPS 809
+T +C+ + C + G C+N G+F C C +G+ G C
Sbjct: 2443 YTTDGRDIDECKVMPNLCTN------GQCINTMGSFRCFCKVGYTTDISGTSCID--LDE 2494
Query: 810 CADSPCRNRATCQDSPQGPRCLCPTGYT----GGSCQTLMDLCAQKPCPRNSHCLQTGPS 865
C+ SP C+++ +C CP GY G +C+ L D C K C+ T
Sbjct: 2495 CSQSPKPCNYICKNTEGSYQCSCPRGYVLQEDGKTCKDL-DECQTKQHNCQFLCVNTLGG 2553
Query: 866 FHCLCLQGWT-GPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ- 923
F C C G+T + + C SLC G+C ++ S+ C C GF
Sbjct: 2554 FTCKCPPGFTQHHTACIDNNECGSQ--------PSLCGAKGICQNTPGSFSCECQRGFSL 2605
Query: 924 ---GSLCQDHVNPCE-SRPCQNGATCMAQPSGYLCQCAPGY----------DGQNCSKEL 969
G C+D V+ C+ + CQ+G C GY C C GY D CS
Sbjct: 2606 DATGLNCED-VDECDGNHRCQHG--CQNILGGYRCGCPQGYIQHYQWNQCVDENECSNP- 2661
Query: 970 DACQSQPCHNHGTCTPKPGGFHCACPPGF----VGLRCEGDVDECLD--QPCHPTGTAAC 1023
+AC S C+N G + CACP GF C DV+EC PC+ C
Sbjct: 2662 NACGSASCYN------TLGSYKCACPSGFSFDQFSSACH-DVNECSSSKNPCN----YGC 2710
Query: 1024 HSLANAFYCQCLPGH 1038
+ + C C PG+
Sbjct: 2711 SNTEGGYLCGCPPGY 2725
Score = 290 bits (741), Expect = 1e-77
Identities = 333/1195 (27%), Positives = 463/1195 (38%), Gaps = 267/1195 (22%)
Query: 155 QLRDFCS--ANPCVNGGVCLATYPQIQCHCPPGFEGHACER--DVNECFQDPGPCPKGTS 210
Q D C AN C+NG C+ T +C C G++ A DV+EC +P C G
Sbjct: 493 QTIDICKHHANLCLNGR-CIPTVSSYRCECNMGYKQDANGDCIDVDECTSNP--CTNG-D 548
Query: 211 CHNTLGSFQCLCPVG-QEGPRCE--LRAGPCPPRG--CSNGGTCQLMPEKDSTFHLCLCP 265
C NT GS+ C C G Q P + + C G C NG D +F C+C
Sbjct: 549 CVNTPGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNT----DGSFQ-CICN 603
Query: 266 PGFIGPDCEVNPDNCVSH-QCQNGGTCQDGL-----DTYTCLCPETWT----GWDCSEDV 315
GF + + NCV H +C C +G+ ++ C+C + G C+ DV
Sbjct: 604 AGF---ELTTDGKNCVDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYCT-DV 659
Query: 316 DECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVG 375
DEC+T G C NG C NS GSF C C G +D + STC +
Sbjct: 660 DECQTPGI--CMNGH-CINSEGSFRCDCPPGLA-----VGMDGRVCVDTHMRSTCYGGIK 711
Query: 376 SFSCLCP-PG---RTGLLCHLEDMCLSQPC-----------HGDA--------------Q 406
C+ P PG ++ C D +PC HG +
Sbjct: 712 KGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINE 771
Query: 407 CSTNP----------LTGSTLCLCQPGY----SGPTCHQDLDECLMAQQGPSPCEHGGSC 452
C+ +P L GS C C GY SG C D+DECL+ + C++G C
Sbjct: 772 CALDPDICANGICENLRGSYRCNCNSGYEPDASGRNCI-DIDECLVNRL---LCDNG-LC 826
Query: 453 LNTPGSFNCLCPPGY---TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQL 509
NTPGS++C CPPGY T + D NEC S PC G+ C + L +F+C C PG +
Sbjct: 827 RNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGA-CRNNLGSFNCECSPGSKLSS 885
Query: 510 CEVETNECASAPC-LNHAD--CHDLLNGFQ-----CICLPGFSGTRCE------------ 549
+ + C LN D C +NG C L G+ CE
Sbjct: 886 TGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGL 945
Query: 550 --------EDIDECRSSP--CANGGQCQDQPGAFHCKCLPGF----EGPRC-QTEVDECL 594
ED++EC P C N G+C + G+FHC+C G G C +++C
Sbjct: 946 ARIKGVTCEDVNECEVFPGVCPN-GRCVNSKGSFHCECPEGLTLDGTGRVCLDIRMEQCY 1004
Query: 595 ----SDPCPVGASCLDLPGAF---FCLCPSGFT-GQLCEVPLCAPNLCQPKQICKDQKDK 646
D C +PG F C C G G CE C PK K+ +
Sbjct: 1005 LKWDEDEC-----IHPVPGKFRMDACCCAVGAAWGTECEE--C------PKPGTKEYE-- 1049
Query: 647 ANCLCPDGSPGCAPPEDNCT-----------------CHHGHCQRS----SCVCDVGWTG 685
LCP G+ G A D T C +G C+ + C C+ G+
Sbjct: 1050 --TLCPRGA-GFANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFAL 1106
Query: 686 PECE---AELGGC-ISAPCAHGGTCYPQPSGYNCTCPTGYTG-----PTCSEEMTACHSG 736
E ++ C IS G C P + C C GY C ++ C
Sbjct: 1107 DMEERNCTDIDECRISPDLCGSGICVNTPGSFECECFEGYESGFMMMKNCM-DIDECERN 1165
Query: 737 PCL-NGGSCNPSPGGYYCTCPPSH----TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSC 791
P L GG+C + G + C CP H + C + +S G CVN GT+ C
Sbjct: 1166 PLLCRGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQC 1225
Query: 792 LCAMGFQGPRCEGKLRPSCAD-SPCRNR-----ATCQDSPQGPRCLCPTGYT----GGSC 841
C G+Q R C D C C +S C C GY G SC
Sbjct: 1226 SCNPGYQAT----PDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSC 1281
Query: 842 QTLMDLCAQKP--CPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSS 899
+ D C P C C + CLC G+ + ++ + +C IDV+
Sbjct: 1282 ADI-DECENNPDICD-GGQCTNIPGEYRCLCYDGF---MASMDMKTC--------IDVNE 1328
Query: 900 LCHNGGLCV-----DSGPSYFCHCPPGF---QGSLCQDHVNPCE--SRPCQNGATCMAQP 949
N +C+ ++ S+ CHC G+ +G+ V+ CE + C A+C+ P
Sbjct: 1329 CDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIP 1388
Query: 950 SGYLCQCAPGYDGQNCS-KELDACQ--SQPCHNHGTCTPKPGGFHCACPPGFV--GLRCE 1004
+ C C G+ G +LD C + C + C PG + CAC GF G C
Sbjct: 1389 GSFKCSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPGSYRCACSEGFTGDGFTC- 1447
Query: 1005 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT----GQWCEVEIDPCHSQPCFHGGT 1060
DVDEC + + C ++ A+ C+C G T + C+ +ID C Q GT
Sbjct: 1448 SDVDECAEN-INLCENGQCLNVPGAYRCECEMGFTPASDSRSCQ-DIDECSFQNICVFGT 1505
Query: 1061 CEATAGSPLGFICHCPKGFE----GPTCSHRAPSCGFHHCHHGGLCLPSP-------KPG 1109
C G F C C G+E G C+ +C + GLC+ +P P
Sbjct: 1506 CNNLPGM---FHCICDDGYELDRTGGNCTDIDECADPINCVN-GLCVNTPGRYECNCPPD 1561
Query: 1110 F---PPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSC 1161
F P C+ G +C P+G G + SC+ G+G C C
Sbjct: 1562 FQLNPTGVGCVDNRVG-NCYLKFGPRGDG-------SLSCNTEIGVGVSRSSCCC 1608
Score = 277 bits (708), Expect = 9e-74
Identities = 354/1381 (25%), Positives = 506/1381 (36%), Gaps = 313/1381 (22%)
Query: 35 CANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSP 94
C NGGTC CQC G++G C P C+N CQNGG C
Sbjct: 153 CMNGGTC-----ADDHCQCQKGYIGTYCGQP-VCENG--CQNGGRC-------------- 190
Query: 95 SPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQC 154
+ P+ C C+ GFTG +C+ + G C Q + + C TG C
Sbjct: 191 --IGPN-RCACVYGFTGPQCERDY----------RTGPCFTQVNNQ---MCQGQLTGIVC 234
Query: 155 QLRDFCSA------NPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKG 208
C+ +PC +C A + P AC+ DV+EC PG C +G
Sbjct: 235 TKTLCCATIGRAWGHPCE---MCPAQPQPCRRGFIPNIRTGACQ-DVDECQAIPGIC-QG 289
Query: 209 TSCHNTLGSFQCLCPVG----------QEGPRCELRAGPCPPRGCSNGGTCQLMPEKDST 258
+C NT+GSF+C CP G ++ C + G C CSN
Sbjct: 290 GNCINTVGSFECRCPAGHKQSETTQKCEDIDECSIIPGICETGECSN----------TVG 339
Query: 259 FHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTC------------LCPETW 306
+ C+CP G++ + C+ Q G C GL C C E
Sbjct: 340 SYFCVCPRGYV---TSTDGSRCID---QRTGMCFSGLVNGRCAQELPGRMTKMQCCCEPG 393
Query: 307 TGWDCSEDVDECETQGPPH----CRNG---GTCQNSAGSFHCVCVSGWGGTSCEENLDDC 359
W + C +G C +G G SAGS GGT
Sbjct: 394 RCWGIGTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSRP-------GGTGGNGFAPSG 446
Query: 360 IAATCAPGSTCIDRVGSFSCLCP-------------PGRTGL--------LC-HLEDMCL 397
PG T + + P P TGL +C H ++CL
Sbjct: 447 NGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHANLCL 506
Query: 398 SQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQ--DLDECLMAQQGPSPCEHGGSCLNT 455
+ C P S C C GY D+DEC +PC + G C+NT
Sbjct: 507 NGRC--------IPTVSSYRCECNMGYKQDANGDCIDVDECT-----SNPCTN-GDCVNT 552
Query: 456 PGSFNCLCPPGY----TGSRCEADHNECLSQP--CHPGSTCLDLLATFHCLCPPGLE--- 506
PGS+ C C G+ T C D +EC+ C G C++ +F C+C G E
Sbjct: 553 PGSYYCKCHAGFQRTPTKQAC-IDIDECIQNGVLCKNG-RCVNTDGSFQCICNAGFELTT 610
Query: 507 -GQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGF----SGTRCEEDIDECRSSPCA 561
G+ C V+ +EC + + C + F+CIC PGF +G C D+DEC++
Sbjct: 611 DGKNC-VDHDECTTTNMCLNGMCINEDGSFKCICKPGFVLAPNGRYC-TDVDECQTPGIC 668
Query: 562 NGGQCQDQPGAFHCKCLPGFE-GPRCQTEVDECLSDPC----PVGASCLDLPGAFF---C 613
G C + G+F C C PG G + VD + C G PGA C
Sbjct: 669 MNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSEC 728
Query: 614 LC--PSGFTGQLCEVPLCAPNLCQPKQICK-------DQKDKANC-LCPDGSPGCAPPED 663
C P G+ C+ P A N + +C D +D C L PD
Sbjct: 729 CCANPDYGFGEPCQ-PCPAKNSAEFHGLCSSGVGITVDGRDINECALDPD---------- 777
Query: 664 NCTCHHGHCQ--RSS--CVCDVGW----TGPECEAELGGC-ISAPCAHGGTCYPQPSGYN 714
C +G C+ R S C C+ G+ +G C ++ C ++ G C P Y+
Sbjct: 778 --ICANGICENLRGSYRCNCNSGYEPDASGRNC-IDIDECLVNRLLCDNGLCRNTPGSYS 834
Query: 715 CTCPTGY---TGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYC 771
CTCP GY T E++ C S PC+N G+C + G + C C P G + ++ C
Sbjct: 835 CTCPPGYVFRTETETCEDINECESNPCVN-GACRNNLGSFNCECSP---GSKLSSTGLIC 890
Query: 772 VSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRC- 830
+ + GT C + Q RCE + + S C RC
Sbjct: 891 ID----------SLKGT----CWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCE 936
Query: 831 ---LCPTGYT---GGSCQTLMDLCAQKP--CPRNSHCLQTGPSFHCLCLQGWTGPLCNLP 882
CP G G +C+ + + C P CP N C+ + SFHC C +G L
Sbjct: 937 LDTACPRGLARIKGVTCEDVNE-CEVFPGVCP-NGRCVNSKGSFHCECPEG-------LT 987
Query: 883 LSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYF----CHCPPGFQ-GSLCQDHVNPCESR 937
L + L ++ L + C+ P F C C G G+ C++ C
Sbjct: 988 LDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKFRMDACCCAVGAAWGTECEE----CPKP 1043
Query: 938 PCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQP-CHNHGTCTPKPGGFHCACPP 996
+ T + +G+ G+ K+++ C++ P +G C G F C C
Sbjct: 1044 GTKEYETLCPRGAGF-ANRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNS 1102
Query: 997 GF---VGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCE----VEIDP 1049
GF + R D+DEC P G+ C + +F C+C G+ + ++ID
Sbjct: 1103 GFALDMEERNCTDIDECRISP-DLCGSGICVNTPGSFECECFEGYESGFMMMKNCMDIDE 1161
Query: 1050 CHSQPCF-HGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCH-HGGLCLPSPK 1107
C P GGTC T GS F C CP G E R + C LC
Sbjct: 1162 CERNPLLCRGGTCVNTEGS---FQCDCPLGHE--LSPSREDCVDINECSLSDNLCRNGKC 1216
Query: 1108 PGF--PPRCACLSGYGGPDCLTPPAPKGCGPPSPC-LYNGSCSETTGLGGPGFRCSCPHS 1164
+C+C GY P +GC C + NG C + CSC
Sbjct: 1217 VNMIGTYQCSCNPGY-----QATPDRQGCTDIDECMIMNGGCDTQCTNSEGSYECSCSEG 1271
Query: 1165 SPGPRCQKPGAKGC----EGRSGDGACDAG-CSGPGGN-----WDGGDCSLGVPDPWKGC 1214
P + C E + CD G C+ G +DG S+ + K C
Sbjct: 1272 ----YALMPDGRSCADIDECENNPDICDGGQCTNIPGEYRCLCYDGFMASMDM----KTC 1323
Query: 1215 PSHSRCWL-----LFRDGQ-------CHPQ------------CDSEECLFDGYDCETPPA 1250
+ C L +F + + CH Q D +EC ++C+ +
Sbjct: 1324 IDVNECDLNSNICMFGECENTKGSFICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHAS 1383
Query: 1251 C 1251
C
Sbjct: 1384 C 1384
Score = 275 bits (702), Expect = 4e-73
Identities = 372/1451 (25%), Positives = 526/1451 (36%), Gaps = 360/1451 (24%)
Query: 25 GLLCGS--FPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQ---FPDPC---QNAQLCQN 76
G CG C NGG C+ G C C GF G C+ PC N Q+CQ
Sbjct: 172 GTYCGQPVCENGCQNGGRCI----GPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQ- 226
Query: 77 GGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQ 136
G ++ T + C + G C+ P P C +RG
Sbjct: 227 -GQLTGIV------------CTKTLCCATIGRAWGHPCEM---CPAQPQPC-RRG----- 264
Query: 137 ASGRPQCSCMPGWTGEQCQLRDFCSANPCV-NGGVCLATYPQIQCHCPPGFE----GHAC 191
+P CQ D C A P + GG C+ T +C CP G + C
Sbjct: 265 --------FIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFECRCPAGHKQSETTQKC 316
Query: 192 ERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG----QEGPRC-ELRAGPCPPRGCSNG 246
E D++EC PG C G C NT+GS+ C+CP G +G RC + R G C G NG
Sbjct: 317 E-DIDECSIIPGICETG-ECSNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMC-FSGLVNG 373
Query: 247 GTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQD-----GLDTYTCL 301
Q +P + T C C PG +C GT + G + Y L
Sbjct: 374 RCAQELPGR-MTKMQCCCEPG----------------RCWGIGTIPEACPVRGSEEYRRL 416
Query: 302 CPE--TWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGG---------- 349
C + G S T G +G G + + G G
Sbjct: 417 CMDGLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGV 476
Query: 350 ------------TSCEENLDDC--IAATCAPGSTCIDRVGSFSCLCPPG---RTGLLCHL 392
T + +D C A C G CI V S+ C C G C
Sbjct: 477 GAGGQGPIITGLTILNQTIDICKHHANLCLNG-RCIPTVSSYRCECNMGYKQDANGDCID 535
Query: 393 EDMCLSQPC-HGDAQCSTNPLTGSTLCLCQPGYSGPTCHQ---DLDECLMAQQGPSPCEH 448
D C S PC +GD C P GS C C G+ Q D+DEC+ Q C++
Sbjct: 536 VDECTSNPCTNGD--CVNTP--GSYYCKCHAGFQRTPTKQACIDIDECI---QNGVLCKN 588
Query: 449 GGSCLNTPGSFNCLCPPGY----TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPG 504
G C+NT GSF C+C G+ G C DH+EC + C++ +F C+C PG
Sbjct: 589 -GRCVNTDGSFQCICNAGFELTTDGKNC-VDHDECTTTNMCLNGMCINEDGSFKCICKPG 646
Query: 505 L----EGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFS-------------GTR 547
G+ C + +EC + + C + F+C C PG + +
Sbjct: 647 FVLAPNGRYC-TDVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRST 705
Query: 548 CEEDIDE---CRSSP---------CAN-----GGQCQDQP----GAFHCKCLPGFEGPRC 586
C I + R P CAN G CQ P FH C G
Sbjct: 706 CYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVD 765
Query: 587 QTEVDECLSDP--CPVGASCLDLPGAFFCLCPSGF----TGQLC-EVPLCAPN--LCQPK 637
+++EC DP C G C +L G++ C C SG+ +G+ C ++ C N LC
Sbjct: 766 GRDINECALDPDICANGI-CENLRGSYRCNCNSGYEPDASGRNCIDIDECLVNRLLCD-N 823
Query: 638 QICKDQKDKANCLCPDGSPGCAPPE--------DNCTCHHGHCQRS----SCVCDVG--- 682
+C++ +C CP G E ++ C +G C+ + +C C G
Sbjct: 824 GLCRNTPGSYSCTCPPGYVFRTETETCEDINECESNPCVNGACRNNLGSFNCECSPGSKL 883
Query: 683 ---------------WTG---PECEAELGGCI--SAPCAHGGTCYPQP---SGYNCTCPT 719
W CE + G S CA G + P + CP
Sbjct: 884 SSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPR 943
Query: 720 GYT---GPTCSEEMTACH--SGPCLNGGSCNPSPGGYYCTCPP----SHTGPQC-QTSTD 769
G G TC E++ C G C N G C S G ++C CP TG C +
Sbjct: 944 GLARIKGVTC-EDVNECEVFPGVCPN-GRCVNSKGSFHCECPEGLTLDGTGRVCLDIRME 1001
Query: 770 YCVSAPCFNGGTCVNR-PGTF---SCLCAMGFQ-GPRCEGKLRPSCAD------------ 812
C ++ C++ PG F +C CA+G G CE +P +
Sbjct: 1002 QCYLK--WDEDECIHPVPGKFRMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFA 1059
Query: 813 ---------------SPCR------NRATCQDSPQGPRCLCPTGYT----------GGSC 841
+ C+ C+++ +C C +G+ C
Sbjct: 1060 NRGDVLTGRPFYKDINECKAFPGMCTYGKCRNTIGSFKCRCNSGFALDMEERNCTDIDEC 1119
Query: 842 QTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCN----LPLSSCQKAALSQGIDV 897
+ DLC + C+ T SF C C +G+ + + C++ L
Sbjct: 1120 RISPDLCG------SGICVNTPGSFECECFEGYESGFMMMKNCMDIDECERNPL------ 1167
Query: 898 SSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQD---HVNPC--ESRPCQNGATCMAQPSGY 952
LC GG CV++ S+ C CP G + S ++ +N C C+NG C+ Y
Sbjct: 1168 --LC-RGGTCVNTEGSFQCDCPLGHELSPSREDCVDINECSLSDNLCRNG-KCVNMIGTY 1223
Query: 953 LCQCAPGY----DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFV----GLRCE 1004
C C PGY D Q C+ ++D C CT G + C+C G+ G C
Sbjct: 1224 QCSCNPGYQATPDRQGCT-DIDECMIMNGGCDTQCTNSEGSYECSCSEGYALMPDGRSC- 1281
Query: 1005 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTG----QWCEVEIDPC--HSQPCFHG 1058
D+DEC + P G C ++ + C C G + C ++++ C +S C
Sbjct: 1282 ADIDECENNPDICDG-GQCTNIPGEYRCLCYDGFMASMDMKTC-IDVNECDLNSNICMF- 1338
Query: 1059 GTCEATAGSPLGFICHCPKGF---EGPTCSHRAPSC--GFHHCHHGGLCLPSPKPGFPPR 1113
G CE T GS FICHC G+ +G T C G H+C CL P +
Sbjct: 1339 GECENTKGS---FICHCQLGYSVKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSF---K 1392
Query: 1114 CACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKP 1173
C+C G+ G + C N C T G +RC+C
Sbjct: 1393 CSCREGWIGNGIKCIDLDECSNGTHQCSINAQCVNTPG----SYRCAC------------ 1436
Query: 1174 GAKGCEGRSGDG-ACD--AGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCH 1230
EG +GDG C C+ + G C L VP ++ C + F
Sbjct: 1437 ----SEGFTGDGFTCSDVDECAENINLCENGQC-LNVPGAYR-----CECEMGFTPASDS 1486
Query: 1231 PQC-DSEECLF 1240
C D +EC F
Sbjct: 1487 RSCQDIDECSF 1497
Score = 201 bits (510), Expect = 8e-51
Identities = 302/1181 (25%), Positives = 415/1181 (35%), Gaps = 236/1181 (19%)
Query: 260 HLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECE 319
++C C G I C S +C NGGTC D C C + + G C + V CE
Sbjct: 128 NMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADD----HCQCQKGYIGTYCGQPV--CE 181
Query: 320 TQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSC 379
C+NGG C G C CV G+ G CE + T C ++ C
Sbjct: 182 NG----CQNGGRC---IGPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVC 234
Query: 380 ---LCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDEC 436
LC H +MC +QP N TG+ QD+DEC
Sbjct: 235 TKTLCCATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGAC--------------QDVDEC 280
Query: 437 LMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY----TGSRCEADHNECLSQP--CHPGSTC 490
Q P C+ GG+C+NT GSF C CP G+ T +CE D +EC P C G C
Sbjct: 281 ---QAIPGICQ-GGNCINTVGSFECRCPAGHKQSETTQKCE-DIDECSIIPGICETGE-C 334
Query: 491 LDLLATFHCLCPPG----LEGQLC-EVETNECASAPCLNHADCHDLLNG----FQCICLP 541
+ + ++ C+CP G +G C + T C S L + C L G QC C P
Sbjct: 335 SNTVGSYFCVCPRGYVTSTDGSRCIDQRTGMCFSG--LVNGRCAQELPGRMTKMQCCCEP 392
Query: 542 GFS---GT---RCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLS 595
G GT C E C +G PG+ + PG G +
Sbjct: 393 GRCWGIGTIPEACPVRGSEEYRRLCMDGLPMGGIPGSAGSR--PGGTGGNGFAPSGNG-N 449
Query: 596 DPCPVGASCLDLPG--AFFCLCPSGFTGQLCEVPLCA--PNLCQPKQICKDQKDKANCLC 651
P G + +PG F G + P+ L Q ICK + LC
Sbjct: 450 GYGPGGTGFIPIPGGNGFSPGVGGAGVGAGGQGPIITGLTILNQTIDICKHHAN----LC 505
Query: 652 PDGSPGCAPPEDN--CTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQ 709
+G C P + C C+ G+ Q ++ C ++ C S PC + G C
Sbjct: 506 LNGR--CIPTVSSYRCECNMGYKQDANGDC----------IDVDECTSNPCTN-GDCVNT 552
Query: 710 PSGYNCTCPTGY----TGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPP----SHTG 761
P Y C C G+ T C + +G G C + G + C C + G
Sbjct: 553 PGSYYCKCHAGFQRTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQCICNAGFELTTDG 612
Query: 762 PQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGF----QGPRCEGKLRPSCADSPCRN 817
C + + C N G C+N G+F C+C GF G C C
Sbjct: 613 KNCVDHDECTTTNMCLN-GMCINEDGSFKCICKPGFVLAPNGRYCTDV--DECQTPGICM 669
Query: 818 RATCQDSPQGPRCLCPTGY-TGGSCQTLMDLCAQKPC---PRNSHCLQTGP----SFHCL 869
C +S RC CP G G + +D + C + C++ P C
Sbjct: 670 NGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTKSECC 729
Query: 870 CLQ---GWTGPLCNLPLSSCQK--AALSQGIDVS-------------SLCHNGGLCVDSG 911
C G+ P P + + S G+ ++ +C N G+C +
Sbjct: 730 CANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICAN-GICENLR 788
Query: 912 PSYFCHCPPGFQ----GSLCQDHVNPC--ESRPCQNGATCMAQPSGYLCQCAPGY----D 961
SY C+C G++ G C D ++ C C NG C P Y C C PGY +
Sbjct: 789 GSYRCNCNSGYEPDASGRNCID-IDECLVNRLLCDNG-LCRNTPGSYSCTCPPGYVFRTE 846
Query: 962 GQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPG----FVGLRCEGDVD-----ECLD 1012
+ C ++++ C+S PC N G C G F+C C PG GL C + D
Sbjct: 847 TETC-EDINECESNPCVN-GACRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQD 904
Query: 1013 QPCHPTGTAA------CHSLANAFYCQC------------LPGHTGQWCEVEIDPCHSQP 1054
C A C +L A+ C L G CE +++ C P
Sbjct: 905 SRCEVNINGATLKSECCATLGAAWGSPCERCELDTACPRGLARIKGVTCE-DVNECEVFP 963
Query: 1055 -CFHGGTCEATAGSPLGFICHCPKG---------------------FEGPTCSHRAPS-- 1090
G C + GS F C CP+G ++ C H P
Sbjct: 964 GVCPNGRCVNSKGS---FHCECPEGLTLDGTGRVCLDIRMEQCYLKWDEDECIHPVPGKF 1020
Query: 1091 -----CGFHHCHHGGLCLPSPKPG---FPPRCACLSGYGG-PDCLT-PPAPKGCGP---- 1136
C G C PKPG + C +G+ D LT P K
Sbjct: 1021 RMDACCCAVGAAWGTECEECPKPGTKEYETLCPRGAGFANRGDVLTGRPFYKDINECKAF 1080
Query: 1137 PSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAG-CSGPG 1195
P C Y G C T G F+C C ++ E R C +G C
Sbjct: 1081 PGMCTY-GKCRNTIG----SFKCRCNSGFALDMEERNCTDIDECRISPDLCGSGICVNTP 1135
Query: 1196 GNWDGGDCSLGVPDPW---KGCPSHSRCW---LLFRDGQC-----HPQCD---SEECLFD 1241
G+++ +C G + K C C LL R G C QCD E
Sbjct: 1136 GSFE-CECFEGYESGFMMMKNCMDIDECERNPLLCRGGTCVNTEGSFQCDCPLGHELSPS 1194
Query: 1242 GYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGG 1282
DC C+ + D C NG C T +C + G
Sbjct: 1195 REDCVDINECSLS-DNLC----RNGKCVNMIGTYQCSCNPG 1230
Score = 166 bits (420), Expect = 2e-40
Identities = 221/889 (24%), Positives = 312/889 (35%), Gaps = 211/889 (23%)
Query: 454 NTPGS-FNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFH--CLCPPGLEGQLC 510
N GS F+ C PG+ + N+C+ C ++C D + C C G C
Sbjct: 87 NVCGSRFHSYCCPGW---KTLPGGNQCIVPICR--NSCGDGFCSRPNMCTCSSGQISSTC 141
Query: 511 EVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQP 570
++ + S C+N C D C C G+ GT C + + E + C NGG+C
Sbjct: 142 GSKSIQQCSVRCMNGGTCAD----DHCQCQKGYIGTYCGQPVCE---NGCQNGGRCI--- 191
Query: 571 GAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCA 630
G C C+ GF GP+C+ + + PC + +C TG +C LC
Sbjct: 192 GPNRCACVYGFTGPQCERDYR---TGPCFTQVNNQ--------MCQGQLTGIVCTKTLCC 240
Query: 631 PNLCQ----PKQICKDQKDKANC-LCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTG 685
+ + P ++C Q P+ G D C G CQ +C+ VG
Sbjct: 241 ATIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQDVDECQAIPGICQGGNCINTVGSFE 300
Query: 686 PECEA------------ELGGCISAP-CAHGGTCYPQPSGYNCTCPTGYT----GPTCSE 728
C A ++ C P G C Y C CP GY G C +
Sbjct: 301 CRCPAGHKQSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPRGYVTSTDGSRCID 360
Query: 729 EMTA-CHSGPCLNGGSCNPSPG---GYYCTCPPSH-----TGPQC---QTSTDY---CV- 772
+ T C SG +NG PG C C P T P+ + S +Y C+
Sbjct: 361 QRTGMCFSG-LVNGRCAQELPGRMTKMQCCCEPGRCWGIGTIPEACPVRGSEEYRRLCMD 419
Query: 773 ---------SAPCFNGGTCVN---------------------------RPGTFSCLCAMG 796
SA GGT N PG G
Sbjct: 420 GLPMGGIPGSAGSRPGGTGGNGFAPSGNGNGYGPGGTGFIPIPGGNGFSPGVGGAGVGAG 479
Query: 797 FQGPRCEGKLRPSCADSPCRNRAT------CQDSPQGPRCLCPTGY---TGGSCQTLMDL 847
QGP G + C++ A C + RC C GY G C +D
Sbjct: 480 GQGPIITGLTILNQTIDICKHHANLCLNGRCIPTVSSYRCECNMGYKQDANGDCID-VDE 538
Query: 848 CAQKPCPRNSHCLQTGPSFHCLCLQGW----TGPLCNLPLSSCQKAALSQGIDVSSLCHN 903
C PC N C+ T S++C C G+ T C + + C + G+ LC N
Sbjct: 539 CTSNPC-TNGDCVNTPGSYYCKCHAGFQRTPTKQAC-IDIDEC----IQNGV----LCKN 588
Query: 904 GGLCVDSGPSYFCHCPPGFQ----GSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPG 959
G CV++ S+ C C GF+ G C DH + C NG C+ + + C C PG
Sbjct: 589 -GRCVNTDGSFQCICNAGFELTTDGKNCVDHDECTTTNMCLNG-MCINEDGSFKCICKPG 646
Query: 960 Y----DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGF-VGL------------R 1002
+ +G+ C+ ++D CQ+ +G C G F C CPPG VG+
Sbjct: 647 FVLAPNGRYCT-DVDECQTPGICMNGHCINSEGSFRCDCPPGLAVGMDGRVCVDTHMRST 705
Query: 1003 CEGDV---------------DECL-----------DQPCHPTGTAACHSLANAFYCQCLP 1036
C G + EC QPC +A H L ++ +
Sbjct: 706 CYGGIKKGVCVRPFPGAVTKSECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVD 765
Query: 1037 GHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFE----GPTCSHRAPSCG 1092
G C ++ D C + G CE GS + C+C G+E G C
Sbjct: 766 GRDINECALDPDICAN------GICENLRGS---YRCNCNSGYEPDASGRNCIDIDECLV 816
Query: 1093 FHHCHHGGLCLPSPKPGFPPRCACLSGY-GGPDCLTPPAPKGCGPPSPCLYNGSCSETTG 1151
GLC +P C C GY + T C +PC+ NG+C G
Sbjct: 817 NRLLCDNGLCRNTPG---SYSCTCPPGYVFRTETETCEDINEC-ESNPCV-NGACRNNLG 871
Query: 1152 LGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSG-------DGACDAGCSG 1193
F C C SPG + G + G D C+ +G
Sbjct: 872 ----SFNCEC---SPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNING 913
Score = 71.2 bits (173), Expect = 9e-12
Identities = 102/393 (25%), Positives = 133/393 (33%), Gaps = 100/393 (25%)
Query: 863 GPSFHCLCLQGWT----GPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHC 918
G FH C GW G C +P+ C+ + G C S P+ C C
Sbjct: 90 GSRFHSYCCPGWKTLPGGNQCIVPI--CRNSC------------GDGFC--SRPN-MCTC 132
Query: 919 PPGFQGSLC-QDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPC 977
G S C + C R C NG TC CQC GY G C + + C++ C
Sbjct: 133 SSGQISSTCGSKSIQQCSVR-CMNGGTCADDH----CQCQKGYIGTYCGQPV--CENG-C 184
Query: 978 HNHGTCTPKPGGFHCACPPGFVGLRCEGD------VDECLDQPCHP-------TGTAACH 1024
N G C G CAC GF G +CE D + +Q C T T C
Sbjct: 185 QNGGRCI---GPNRCACVYGFTGPQCERDYRTGPCFTQVNNQMCQGQLTGIVCTKTLCCA 241
Query: 1025 SLANAFYCQC--------------LPGHTGQWCEVEIDPCHSQP-CFHGGTCEATAGSPL 1069
++ A+ C +P C+ ++D C + P GG C T GS
Sbjct: 242 TIGRAWGHPCEMCPAQPQPCRRGFIPNIRTGACQ-DVDECQAIPGICQGGNCINTVGS-- 298
Query: 1070 GFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPP 1129
F C CP G + + + C C S PG C + G C+ P
Sbjct: 299 -FECRCPAGHKQSETTQK--------CEDIDEC--SIIPGICETGECSNTVGSYFCVCPR 347
Query: 1130 APKGCGPPSPC-----------LYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGA--K 1176
S C L NG C++ +C C PG RC G +
Sbjct: 348 GYVTSTDGSRCIDQRTGMCFSGLVNGRCAQELPGRMTKMQCCC---EPG-RCWGIGTIPE 403
Query: 1177 GCEGRSG--------DGACDAGCSGPGGNWDGG 1201
C R DG G G G+ GG
Sbjct: 404 ACPVRGSEEYRRLCMDGLPMGGIPGSAGSRPGG 436
Score = 45.8 bits (107), Expect = 4e-04
Identities = 46/184 (25%), Positives = 64/184 (34%), Gaps = 46/184 (25%)
Query: 1019 GTAACHSLANAFYC---QCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGF---- 1071
G C S +++ C + LPG G C V I C + G GF
Sbjct: 85 GPNVCGSRFHSYCCPGWKTLPG--GNQCIVPI-------------CRNSCGD--GFCSRP 127
Query: 1072 -ICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPA 1130
+C C G TC ++ C +GG C C C GY G C P
Sbjct: 128 NMCTCSSGQISSTCGSKSIQQCSVRCMNGGTCADD-------HCQCQKGYIGTYCGQPVC 180
Query: 1131 PKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKG-CEGRSGDGACDA 1189
GC C+ GP RC+C + GP+C++ G C + + C
Sbjct: 181 ENGCQNGGRCI------------GPN-RCACVYGFTGPQCERDYRTGPCFTQVNNQMCQG 227
Query: 1190 GCSG 1193
+G
Sbjct: 228 QLTG 231
>gi|112420992 crumbs homolog 2 [Homo sapiens]
Length = 1285
Score = 325 bits (833), Expect = 3e-88
Identities = 165/415 (39%), Positives = 211/415 (50%), Gaps = 29/415 (6%)
Query: 396 CLSQPCHGDAQCSTNPLTGSTLCLCQP-GYSGPTCHQDLDECLMAQQGPSPCEHGGSCLN 454
C S PC +C G T +P G + CH L QGP P
Sbjct: 42 CASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHG---ALCVPQGPDPT-------- 90
Query: 455 TPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVET 514
F C C PG+ G RCE D +EC S+PCH G+TC +L + C CP G G CE+E
Sbjct: 91 ---GFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEV 147
Query: 515 NECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFH 574
+ECASAPCL+ C D + F+C+C PG+ GTRC+ D+DEC+S PCA+GG C D F
Sbjct: 148 DECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFR 207
Query: 575 CKCL-PGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEV--PLCAP 631
C C G+EG C+ EV EC S PC ASCL+ G+F CLC G++G+LCEV CA
Sbjct: 208 CDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECAS 267
Query: 632 NLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAE 691
+ CQ C + D A G A P H C C G+ G +C E
Sbjct: 268 SPCQHGGRCLQRSDPALY----GGVQAAFPG---AFSFRHAAGFLCHCPPGFEGADCGVE 320
Query: 692 LGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGY 751
+ C S PC +GG C P+G+ C CP GY GPTC E++ C S PCL+GG+C+ + GY
Sbjct: 321 VDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGY 380
Query: 752 YCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCV----NRPGTFSCLCAMGFQGPRC 802
C CP + G C C C TC+ + ++ C C G GP C
Sbjct: 381 ICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
Score = 300 bits (768), Expect = 9e-81
Identities = 158/417 (37%), Positives = 201/417 (48%), Gaps = 53/417 (12%)
Query: 238 CPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTC-QDGLD 296
C C+ G CQ T C P + P C + C +G C G D
Sbjct: 42 CASDPCAPGTECQATESGGYT-----CGP--------MEPRGCATQPCHHGALCVPQGPD 88
Query: 297 T--YTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEE 354
+ C C + G C D+DEC ++ C +G TC+N A + C C G+ G +CE
Sbjct: 89 PTGFRCYCVPGFQGPRCELDIDECASRP---CHHGATCRNLADRYECHCPLGYAGVTCEM 145
Query: 355 NLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DMCLSQPCHGDAQCSTNPLT 413
+D+C +A C G +C+D VGSF C+C PG G C L+ D C SQPC C + L
Sbjct: 146 EVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTC--HDLV 203
Query: 414 GSTLCLCQ-PGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRC 472
C C GY G C +++ EC A PCEH SCL GSF CLC PGY+G C
Sbjct: 204 NGFRCDCAGTGYEGTHCEREVLECASA-----PCEHNASCLEGLGSFRCLCWPGYSGELC 258
Query: 473 EADHNECLSQPCHPGSTCLDL---------------------LATFHCLCPPGLEGQLCE 511
E D +EC S PC G CL A F C CPPG EG C
Sbjct: 259 EVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCG 318
Query: 512 VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPG 571
VE +ECAS PCLN C DL NGFQC C G++G CEED+DEC S PC +GG C D
Sbjct: 319 VEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVA 378
Query: 572 AFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDL----PGAFFCLCPSGFTGQLC 624
+ C+C + G C ++ C CP+ A+C+ + ++ C CP G G C
Sbjct: 379 GYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFC 435
Score = 288 bits (736), Expect = 5e-77
Identities = 156/429 (36%), Positives = 196/429 (45%), Gaps = 51/429 (11%)
Query: 723 GPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTC 782
G SE +AC S PC G C + G Y P G C + PC +G C
Sbjct: 32 GTVPSEPPSACASDPCAPGTECQATESGGYTCGPMEPRG---------CATQPCHHGALC 82
Query: 783 VNR---PGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGG 839
V + P F C C GFQGPRCE + CA PC + ATC++ C CP GY G
Sbjct: 83 VPQGPDPTGFRCYCVPGFQGPRCELDI-DECASRPCHHGATCRNLADRYECHCPLGYAGV 141
Query: 840 SCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSS 899
+C+ +D CA PC CL SF C+C G+ G C L L CQ S
Sbjct: 142 TCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQ----------SQ 191
Query: 900 LCHNGGLCVDSGPSYFCHCP-PGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAP 958
C +GG C D + C C G++G+ C+ V C S PC++ A+C+ + C C P
Sbjct: 192 PCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWP 251
Query: 959 GYDGQNCSKELDACQSQPCHNHGTCTPK-------------PG--------GFHCACPPG 997
GY G+ C + D C S PC + G C + PG GF C CPPG
Sbjct: 252 GYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPG 311
Query: 998 FVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFH 1057
F G C +VDEC +PC G C L N F C C G+ G CE ++D C S PC H
Sbjct: 312 FEGADCGVEVDECASRPCLNGG--HCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLH 369
Query: 1058 GGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPR-CAC 1116
GGTC T G+IC CP+ + G CS + C H C C+P + G C C
Sbjct: 370 GGTCSDTVA---GYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHC 426
Query: 1117 LSGYGGPDC 1125
G GP C
Sbjct: 427 PPGTHGPFC 435
Score = 283 bits (724), Expect = 1e-75
Identities = 148/426 (34%), Positives = 191/426 (44%), Gaps = 43/426 (10%)
Query: 629 CAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGH-CQRSS-------CVCD 680
CA + C P C+ + P GCA CHHG C C C
Sbjct: 42 CASDPCAPGTECQATESGGYTCGPMEPRGCATQP----CHHGALCVPQGPDPTGFRCYCV 97
Query: 681 VGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLN 740
G+ GP CE ++ C S PC HG TC Y C CP GY G TC E+ C S PCL+
Sbjct: 98 PGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDECASAPCLH 157
Query: 741 GGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCA-MGFQG 799
GGSC G + C C P + G +CQ D C S PC +GGTC + F C CA G++G
Sbjct: 158 GGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEG 217
Query: 800 PRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHC 859
CE ++ CA +PC + A+C + RCLC GY+G C+ D CA PC C
Sbjct: 218 THCEREVL-ECASAPCEHNASCLEGLGSFRCLCWPGYSGELCEVDEDECASSPCQHGGRC 276
Query: 860 LQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCP 919
LQ AL G+ + G + CHCP
Sbjct: 277 LQR------------------------SDPALYGGVQAA---FPGAFSFRHAAGFLCHCP 309
Query: 920 PGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHN 979
PGF+G+ C V+ C SRPC NG C P+G+ C C GY G C +++D C S PC +
Sbjct: 310 PGFEGADCGVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLH 369
Query: 980 HGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTA--ACHSLANAFYCQCLPG 1037
GTC+ G+ C CP + G C + C C T S +++ C C PG
Sbjct: 370 GGTCSDTVAGYICRCPETWGGRDCSVQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPG 429
Query: 1038 HTGQWC 1043
G +C
Sbjct: 430 THGPFC 435
Score = 260 bits (664), Expect = 1e-68
Identities = 148/444 (33%), Positives = 189/444 (42%), Gaps = 99/444 (22%)
Query: 544 SGTRCEEDIDECRSSPCANGGQCQ--------------------------------DQPG 571
+GT E C S PCA G +CQ P
Sbjct: 31 AGTVPSEPPSACASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPT 90
Query: 572 AFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPL--C 629
F C C+PGF+GPRC+ ++DEC S PC GA+C +L + C CP G+ G CE+ + C
Sbjct: 91 GFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEVDEC 150
Query: 630 APNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECE 689
A C C D C+ CAP G+ G C+
Sbjct: 151 ASAPCLHGGSCLDGVGSFRCV-------CAP---------------------GYGGTRCQ 182
Query: 690 AELGGCISAPCAHGGTCYPQPSGYNCTCP-TGYTGPTCSEEMTACHSGPCLNGGSCNPSP 748
+L C S PCAHGGTC+ +G+ C C TGY G C E+ C S PC + SC
Sbjct: 183 LDLDECQSQPCAHGGTCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGL 242
Query: 749 GGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNR-------------PGTFS----- 790
G + C C P ++G C+ D C S+PC +GG C+ R PG FS
Sbjct: 243 GSFRCLCWPGYSGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAA 302
Query: 791 ---CLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDL 847
C C GF+G C G CA PC N CQD P G +C CP GY G +C+ +D
Sbjct: 303 GFLCHCPPGFEGADC-GVEVDECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTCEEDVDE 361
Query: 848 CAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLC 907
C PC C T + C C + W G C++ L+ CQ C C
Sbjct: 362 CLSDPCLHGGTCSDTVAGYICRCPETWGGRDCSVQLTGCQ----------GHTCPLAATC 411
Query: 908 V---DSG-PSYFCHCPPGFQGSLC 927
+ +SG SY CHCPPG G C
Sbjct: 412 IPIFESGVHSYVCHCPPGTHGPFC 435
Score = 253 bits (647), Expect = 1e-66
Identities = 143/427 (33%), Positives = 187/427 (43%), Gaps = 60/427 (14%)
Query: 771 CVSAPCFNGGTC-VNRPGTFSCLCAMGFQGPRCEGKLRP-SCADSPCRNRATCQDSPQGP 828
C S PC G C G ++C G + P CA PC + A C PQGP
Sbjct: 42 CASDPCAPGTECQATESGGYTC------------GPMEPRGCATQPCHHGALCV--PQGP 87
Query: 829 -----RCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPL 883
RC C G+ G C+ +D CA +PC + C + C C G+ G C + +
Sbjct: 88 DPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCPLGYAGVTCEMEV 147
Query: 884 SSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGA 943
C A C +GG C+D S+ C C PG+ G+ CQ ++ C+S+PC +G
Sbjct: 148 DECASAP----------CLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAHGG 197
Query: 944 TCMAQPSGYLCQCA-PGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLR 1002
TC +G+ C CA GY+G +C +E+ C S PC ++ +C G F C C PG+ G
Sbjct: 198 TCHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGYSGEL 257
Query: 1003 CEGDVDECLDQPCHPTGTAACHS-------------------LANAFYCQCLPGHTGQWC 1043
CE D DEC PC G S A F C C PG G C
Sbjct: 258 CEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADC 317
Query: 1044 EVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCL 1103
VE+D C S+PC +GG C+ P GF CHCP G+ GPTC C C HGG C
Sbjct: 318 GVEVDECASRPCLNGGHCQDL---PNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCS 374
Query: 1104 PSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPH 1163
+ C C +GG DC GC + C +C G + C CP
Sbjct: 375 DTVAGYI---CRCPETWGGRDCSVQLT--GCQGHT-CPLAATCIPIFESGVHSYVCHCPP 428
Query: 1164 SSPGPRC 1170
+ GP C
Sbjct: 429 GTHGPFC 435
Score = 242 bits (617), Expect = 3e-63
Identities = 199/677 (29%), Positives = 268/677 (39%), Gaps = 95/677 (14%)
Query: 4 PSLLLLLLLLLLLCVSVVRPRGLLCGSFP---------EPCANGGTCLSLSLGQGTCQCA 54
P L +LLLLL ++ LL G+ P +PCA G C + G TC
Sbjct: 11 PQALASVLLLLLWAPAL----SLLAGTVPSEPPSACASDPCAPGTECQATESGGYTC--- 63
Query: 55 PGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERC 114
G + PC + LC +P P P F C C+PGF G RC
Sbjct: 64 -GPMEPRGCATQPCHHGALC---------------VPQGPDPT--GFRCYCVPGFQGPRC 105
Query: 115 QAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR-DFCSANPCVNGGVCLA 173
+ + D C C C A R +C C G+ G C++ D C++ PC++GG CL
Sbjct: 106 ELDI-DECASRPCHHGATCRNLAD-RYECHCPLGYAGVTCEMEVDECASAPCLHGGSCLD 163
Query: 174 TYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCP-VGQEGPRCE 232
+C C PG+ G C+ D++EC P C G +CH+ + F+C C G EG CE
Sbjct: 164 GVGSFRCVCAPGYGGTRCQLDLDECQSQP--CAHGGTCHDLVNGFRCDCAGTGYEGTHCE 221
Query: 233 LRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQ 292
C C + +C E +F CLC PG+ G CEV+ D C S CQ+GG C
Sbjct: 222 REVLECASAPCEHNASCL---EGLGSFR-CLCWPGYSGELCEVDEDECASSPCQHGGRCL 277
Query: 293 DGLDT---------------------YTCLCPETWTGWDCSEDVDECETQGPPHCRNGGT 331
D + C CP + G DC +VDEC ++ C NGG
Sbjct: 278 QRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGVEVDECASRP---CLNGGH 334
Query: 332 CQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCH 391
CQ+ F C C G+ G +CEE++D+C++ C G TC D V + C CP G C
Sbjct: 335 CQDLPNGFQCHCPDGYAGPTCEEDVDECLSDPCLHGGTCSDTVAGYICRCPETWGGRDCS 394
Query: 392 LE-DMCLSQPCHGDAQCSTNPLTG--STLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEH 448
++ C C A C +G S +C C PG GP C Q+ +MA
Sbjct: 395 VQLTGCQGHTCPLAATCIPIFESGVHSYVCHCPPGTHGPFCGQNTTFSVMAGSPIQASVP 454
Query: 449 GGSCLNTPGSFNCLCPPGYTGSRCEADHN-ECLSQPCHPGSTCLDLLATFHCLCPPGL-- 505
G L F P G +R + + E +T T L P L
Sbjct: 455 AGGPLGLALRFRTTLPAGTLATRNDTKESLELALVAATLQATLWSYSTTVLVLRLPDLAL 514
Query: 506 -EGQLCEVET--NECASAPCLNHADCHDLLNGFQCIC------LPGFSGTRCEEDIDECR 556
+G +VE + L H C L C+ S T I +
Sbjct: 515 NDGHWHQVEVVLHLATLELRLWHEGCPARL----CVASGPVALASTASATPLPAGISSAQ 570
Query: 557 SSPCANGGQCQDQPGAFHCKCLPGFEGPR----CQTEVDECLSDPCPVGASCLDLPGAFF 612
G QD H LP G C+ ++C PC G SC+DL F
Sbjct: 571 LGDATFAGCLQDVRVDGHL-LLPEDLGENVLLGCERR-EQCRPLPCVHGGSCVDLWTHFR 628
Query: 613 CLCPSGFTGQLC--EVP 627
C C G C E+P
Sbjct: 629 CDCARPHRGPTCADEIP 645
Score = 226 bits (575), Expect = 2e-58
Identities = 124/342 (36%), Positives = 152/342 (44%), Gaps = 73/342 (21%)
Query: 901 CHNGGLCVDSGPS---YFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCA 957
CH+G LCV GP + C+C PGFQG C+ ++ C SRPC +GATC Y C C
Sbjct: 76 CHHGALCVPQGPDPTGFRCYCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECHCP 135
Query: 958 PGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHP 1017
GY G C E+D C S PC + G+C G F C C PG+ G RC+ D+DEC QPC
Sbjct: 136 LGYAGVTCEMEVDECASAPCLHGGSCLDGVGSFRCVCAPGYGGTRCQLDLDECQSQPCAH 195
Query: 1018 TGTAACHSLANAFYCQCL---------------------------------------PGH 1038
GT CH L N F C C PG+
Sbjct: 196 GGT--CHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCLEGLGSFRCLCWPGY 253
Query: 1039 TGQWCEVEIDPCHSQPCFHGGTCEATAGSPL------------------GFICHCPKGFE 1080
+G+ CEV+ D C S PC HGG C + L GF+CHCP GFE
Sbjct: 254 SGELCEVDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFE 313
Query: 1081 GPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPC 1140
G C C C +GG C P GF +C C GY GP C C PC
Sbjct: 314 GADCGVEVDECASRPCLNGGHCQDLPN-GF--QCHCPDGYAGPTC--EEDVDEC-LSDPC 367
Query: 1141 LYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRS 1182
L+ G+CS+T G+ C CP + G C GC+G +
Sbjct: 368 LHGGTCSDTVA----GYICRCPETWGGRDCSVQ-LTGCQGHT 404
Score = 118 bits (296), Expect = 5e-26
Identities = 65/175 (37%), Positives = 83/175 (47%), Gaps = 5/175 (2%)
Query: 443 PSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCP 502
PSPC H G+C + +F C C PG+ G RCEA + C S PC G F C CP
Sbjct: 1062 PSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCP 1121
Query: 503 PGLEGQLCE--VETNECA-SAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSP 559
PG G C V + EC+ + CL+ + C C CL G +G RC+ C ++P
Sbjct: 1122 PGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANP 1181
Query: 560 CANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCL 614
C NGG C+ G C C F G C EV + L P P + +P A CL
Sbjct: 1182 CLNGGTCRAAGGVSECICNARFSGQFC--EVAKGLPLPLPFPLLEVAVPAACACL 1234
Score = 117 bits (294), Expect = 9e-26
Identities = 60/152 (39%), Positives = 74/152 (48%), Gaps = 5/152 (3%)
Query: 479 CLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNG-FQC 537
C PC C DL F C C PG EG CE + C SAPC CH +G F+C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCAR-GRCHTHPDGRFEC 1118
Query: 538 ICLPGFSGTRCEEDID--ECRSS-PCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECL 594
C PGF G RC + EC + C +G C+ A +C CL G G RCQ C
Sbjct: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCE 1178
Query: 595 SDPCPVGASCLDLPGAFFCLCPSGFTGQLCEV 626
++PC G +C G C+C + F+GQ CEV
Sbjct: 1179 ANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 114 bits (285), Expect = 1e-24
Identities = 59/141 (41%), Positives = 74/141 (52%), Gaps = 7/141 (4%)
Query: 517 CASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQP-GAFHC 575
CA +PCL+ C DL + F C C PG+ G RCE +D C S+PCA G +C P G F C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRFEC 1118
Query: 576 KCLPGFEGPRCQTEV--DEC-LSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPL--CA 630
+C PGF GPRC+ V EC L+ C G+ C A C C G GQ C+VP C
Sbjct: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCE 1178
Query: 631 PNLCQPKQICKDQKDKANCLC 651
N C C+ + C+C
Sbjct: 1179 ANPCLNGGTCRAAGGVSECIC 1199
Score = 112 bits (281), Expect = 3e-24
Identities = 61/160 (38%), Positives = 76/160 (47%), Gaps = 16/160 (10%)
Query: 654 GSPGCAPPEDNCTCHHGHCQ----RSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQ 709
G+P CAP H G C+ +C C GW GP CEA + C SAPCA G C+
Sbjct: 1056 GAPVCAPSP---CLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCAR-GRCHTH 1111
Query: 710 PSG-YNCTCPTGYTGPTC-----SEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQ 763
P G + C CP G+ GP C S+E + + CL+G C C+C G +
Sbjct: 1112 PDGRFECRCPPGFGGPRCRLPVPSKECSL--NVTCLDGSPCEGGSPAANCSCLEGLAGQR 1169
Query: 764 CQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCE 803
CQ T C + PC NGGTC G C+C F G CE
Sbjct: 1170 CQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 112 bits (281), Expect = 3e-24
Identities = 70/192 (36%), Positives = 81/192 (42%), Gaps = 25/192 (13%)
Query: 934 CESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGG-FHC 992
C PC + C + C C PG++G C +D C S PC G C P G F C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCAR-GRCHTHPDGRFEC 1118
Query: 993 ACPPGFVGLRCEGDV--DEC-LDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDP 1049
CPPGF G RC V EC L+ C + C + A C CL G GQ C+V P
Sbjct: 1119 RCPPGFGGPRCRLPVPSKECSLNVTC--LDGSPCEGGSPAANCSCLEGLAGQRCQVPTLP 1176
Query: 1050 CHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKP- 1108
C + PC +GGTC A G C C F G C GL LP P P
Sbjct: 1177 CEANPCLNGGTCRAAGGVS---ECICNARFSGQFCEVAK-----------GLPLPLPFPL 1222
Query: 1109 ---GFPPRCACL 1117
P CACL
Sbjct: 1223 LEVAVPAACACL 1234
Score = 109 bits (273), Expect = 2e-23
Identities = 56/181 (30%), Positives = 78/181 (43%), Gaps = 10/181 (5%)
Query: 695 CISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYY-C 753
C +PC H G C + C C G+ GP C + CHS PC G C+ P G + C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARG-RCHTHPDGRFEC 1118
Query: 754 TCPPSHTGPQCQ---TSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSC 810
CPP GP+C+ S + ++ C +G C +C C G G RC+ P C
Sbjct: 1119 RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLP-C 1177
Query: 811 ADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLC 870
+PC N TC+ + C+C ++G C+ L P P L+ C C
Sbjct: 1178 EANPCLNGGTCRAAGGVSECICNARFSGQFCEVAKGL----PLPLPFPLLEVAVPAACAC 1233
Query: 871 L 871
L
Sbjct: 1234 L 1234
Score = 103 bits (257), Expect = 2e-21
Identities = 55/164 (33%), Positives = 69/164 (42%), Gaps = 9/164 (5%)
Query: 802 CEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQ 861
C G P CA SPC + C+D C C G+ G C+ +D C PC R
Sbjct: 1054 CRGA--PVCAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTH 1111
Query: 862 TGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPG 921
F C C G+ GP C LP+ S+ ++ C +G C P+ C C G
Sbjct: 1112 PDGRFECRCPPGFGGPRCRLPVP-------SKECSLNVTCLDGSPCEGGSPAANCSCLEG 1164
Query: 922 FQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNC 965
G CQ PCE+ PC NG TC A C C + GQ C
Sbjct: 1165 LAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFC 1208
Score = 102 bits (254), Expect = 4e-21
Identities = 61/186 (32%), Positives = 81/186 (43%), Gaps = 19/186 (10%)
Query: 140 RPQCSCMPG-------WTGEQ-----CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFE 187
RP+ PG W G C+ C+ +PC++ G C + C C PG+E
Sbjct: 1028 RPRPGAAPGAREHFASWPGTPAPILGCRGAPVCAPSPCLHDGACRDLFDAFACACGPGWE 1087
Query: 188 GHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGG 247
G CE V+ C PC +G + G F+C CP G GPRC L P P + CS
Sbjct: 1088 GPRCEAHVDPCHS--APCARGRCHTHPDGRFECRCPPGFGGPRCRL---PVPSKECSLNV 1142
Query: 248 TC--QLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPET 305
TC E S C C G G C+V C ++ C NGGTC+ C+C
Sbjct: 1143 TCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNAR 1202
Query: 306 WTGWDC 311
++G C
Sbjct: 1203 FSGQFC 1208
Score = 101 bits (252), Expect = 6e-21
Identities = 57/154 (37%), Positives = 73/154 (47%), Gaps = 15/154 (9%)
Query: 555 CRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCL 614
C SPC + G C+D AF C C PG+EGPRC+ VD C S PC G G F C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
Query: 615 CPSGFTGQLCEVPL----CAPNL-CQPKQICKDQKDKANCLCPDGSPG------CAPPED 663
CP GF G C +P+ C+ N+ C C+ ANC C +G G P E
Sbjct: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
Query: 664 NCTCHHGHCQR----SSCVCDVGWTGPECEAELG 693
N + G C+ S C+C+ ++G CE G
Sbjct: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFCEVAKG 1213
Score = 101 bits (251), Expect = 8e-21
Identities = 54/155 (34%), Positives = 70/155 (45%), Gaps = 10/155 (6%)
Query: 202 PGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHL 261
P PC +C + +F C C G EGPRCE PC C+ G C P D F
Sbjct: 1062 PSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCAR-GRCHTHP--DGRFE- 1117
Query: 262 CLCPPGFIGPDCEV---NPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDEC 318
C CPPGF GP C + + + ++ C +G C+ G C C E G C C
Sbjct: 1118 CRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC 1177
Query: 319 ETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCE 353
E C NGGTC+ + G C+C + + G CE
Sbjct: 1178 EAN---PCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 99.4 bits (246), Expect = 3e-20
Identities = 65/203 (32%), Positives = 88/203 (43%), Gaps = 12/203 (5%)
Query: 42 LSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSF 101
L L L + APG +P C+ C P+P + L +F
Sbjct: 1022 LPLPLARPRPGAAPGAREHFASWPGTPAPILGCRGAPVCA---PSPCLHDGACRDLFDAF 1078
Query: 102 LCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQL---RD 158
C C PG+ G RC+A + DPC + C+ RGRCH GR +C C PG+ G +C+L
Sbjct: 1079 ACACGPGWEGPRCEAHV-DPCHSAPCA-RGRCHTHPDGRFECRCPPGFGGPRCRLPVPSK 1136
Query: 159 FCSAN-PCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGS 217
CS N C++G C P C C G G C+ C + PC G +C G
Sbjct: 1137 ECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPC--EANPCLNGGTCRAAGGV 1194
Query: 218 FQCLCPVGQEGPRCELRAG-PCP 239
+C+C G CE+ G P P
Sbjct: 1195 SECICNARFSGQFCEVAKGLPLP 1217
Score = 96.7 bits (239), Expect = 2e-19
Identities = 85/305 (27%), Positives = 104/305 (34%), Gaps = 49/305 (16%)
Query: 1014 PCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFIC 1073
P P A A CQ +E C +QPC HG C P GF C
Sbjct: 35 PSEPPSACASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRC 94
Query: 1074 HCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKG 1133
+C GF+GP C C CHHG C C C GY G C
Sbjct: 95 YCVPGFQGPRCELDIDECASRPCHHGATC---RNLADRYECHCPLGYAGVTC--EMEVDE 149
Query: 1134 CGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQ--------KPGAKG--CEGRSG 1183
C +PCL+ GSC + G FRC C G RCQ +P A G C
Sbjct: 150 CA-SAPCLHGGSCLDGVG----SFRCVCAPGYGGTRCQLDLDECQSQPCAHGGTCHDLVN 204
Query: 1184 DGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWL----LFRDGQCHPQCDSEECL 1239
CD C+G G ++G C V + H+ L FR C P E C
Sbjct: 205 GFRCD--CAGTG--YEGTHCEREVLECASAPCEHNASCLEGLGSFR-CLCWPGYSGELCE 259
Query: 1240 FDGYDCETPP--------------------ACTPAYDQYCHDHFHNGHCEKGCNTAECGW 1279
D +C + P A P + H HC G A+CG
Sbjct: 260 VDEDECASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCHCPPGFEGADCGV 319
Query: 1280 DGGDC 1284
+ +C
Sbjct: 320 EVDEC 324
Score = 96.7 bits (239), Expect = 2e-19
Identities = 46/151 (30%), Positives = 62/151 (41%), Gaps = 2/151 (1%)
Query: 733 CHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCL 792
C PCL+ G+C + C C P GP+C+ D C SAPC G + G F C
Sbjct: 1060 CAPSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECR 1119
Query: 793 CAMGFQGPRCEGKL--RPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQ 850
C GF GPRC + + + C + + C+ C C G G CQ C
Sbjct: 1120 CPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSCLEGLAGQRCQVPTLPCEA 1179
Query: 851 KPCPRNSHCLQTGPSFHCLCLQGWTGPLCNL 881
PC C G C+C ++G C +
Sbjct: 1180 NPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 95.5 bits (236), Expect = 5e-19
Identities = 57/171 (33%), Positives = 80/171 (46%), Gaps = 17/171 (9%)
Query: 882 PLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQN 941
P+ C+ A + S C + G C D ++ C C PG++G C+ HV+PC S PC
Sbjct: 1050 PILGCRGAPVC----APSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCAR 1105
Query: 942 GATCMAQPSG-YLCQCAPGYDGQNCSKELDACQSQPCHNHGTC---TPKPGG---FHCAC 994
G C P G + C+C PG+ G C + S+ C + TC +P GG +C+C
Sbjct: 1106 G-RCHTHPDGRFECRCPPGFGGPRCRLPV---PSKECSLNVTCLDGSPCEGGSPAANCSC 1161
Query: 995 PPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEV 1045
G G RC+ C PC GT C + C C +GQ+CEV
Sbjct: 1162 LEGLAGQRCQVPTLPCEANPCLNGGT--CRAAGGVSECICNARFSGQFCEV 1210
Score = 88.2 bits (217), Expect = 7e-17
Identities = 59/168 (35%), Positives = 72/168 (42%), Gaps = 27/168 (16%)
Query: 32 PEPCANGGTCLSLSLGQGTCQCAPGFLGETCQ-FPDPCQNAQLCQNGGSCQALLPAPLGL 90
P PC + G C L C C PG+ G C+ DPC +A + G C P G
Sbjct: 1062 PSPCLHDGACRDL-FDAFACACGPGWEGPRCEAHVDPCHSAPCAR--GRCHT---HPDG- 1114
Query: 91 PSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQA---SGRP--QCSC 145
F C C PGF G RC+ P P CS C + G P CSC
Sbjct: 1115 ---------RFECRCPPGFGGPRCRL----PVPSKECSLNVTCLDGSPCEGGSPAANCSC 1161
Query: 146 MPGWTGEQCQLRDF-CSANPCVNGGVCLATYPQIQCHCPPGFEGHACE 192
+ G G++CQ+ C ANPC+NGG C A +C C F G CE
Sbjct: 1162 LEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 88.2 bits (217), Expect = 7e-17
Identities = 48/155 (30%), Positives = 68/155 (43%), Gaps = 11/155 (7%)
Query: 323 PPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCP 382
P C + G C++ +F C C GW G CE ++D C +A CA G G F C CP
Sbjct: 1062 PSPCLHDGACRDLFDAFACACGPGWEGPRCEAHVDPCHSAPCARGRCHTHPDGRFECRCP 1121
Query: 383 PGRTGLLCHL----EDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLM 438
PG G C L ++ L+ C + C + + C C G +G C C
Sbjct: 1122 PGFGGPRCRLPVPSKECSLNVTCLDGSPCEGG--SPAANCSCLEGLAGQRCQVPTLPC-- 1177
Query: 439 AQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCE 473
+PC +GG+C G C+C ++G CE
Sbjct: 1178 ---EANPCLNGGTCRAAGGVSECICNARFSGQFCE 1209
Score = 80.5 bits (197), Expect = 2e-14
Identities = 48/169 (28%), Positives = 67/169 (39%), Gaps = 5/169 (2%)
Query: 225 GQEGPRCELRAGP-CPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSH 283
G P R P C P C + G C+ + + + C C PG+ GP CE + D C S
Sbjct: 1046 GTPAPILGCRGAPVCAPSPCLHDGACRDLFDAFA----CACGPGWEGPRCEAHVDPCHSA 1101
Query: 284 QCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVC 343
C G + C CP + G C V E C +G C+ + + +C C
Sbjct: 1102 PCARGRCHTHPDGRFECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSC 1161
Query: 344 VSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHL 392
+ G G C+ C A C G TC G C+C +G C +
Sbjct: 1162 LEGLAGQRCQVPTLPCEANPCLNGGTCRAAGGVSECICNARFSGQFCEV 1210
Score = 73.9 bits (180), Expect = 1e-12
Identities = 43/124 (34%), Positives = 46/124 (37%), Gaps = 10/124 (8%)
Query: 1050 CHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPG 1109
C PC H G C + F C C G+EGP C C C G C P
Sbjct: 1060 CAPSPCLHDGACRDLFDA---FACACGPGWEGPRCEAHVDPCHSAPCARGR-CHTHPDGR 1115
Query: 1110 FPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPR 1169
F C C G+GGP C P K C CL C G P CSC G R
Sbjct: 1116 F--ECRCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEG----GSPAANCSCLEGLAGQR 1169
Query: 1170 CQKP 1173
CQ P
Sbjct: 1170 CQVP 1173
Score = 69.7 bits (169), Expect = 3e-11
Identities = 75/294 (25%), Positives = 113/294 (38%), Gaps = 34/294 (11%)
Query: 490 CL-DLLATFHCLCPPGL-EGQLCEVETNE-CASAPCLNHADCHDLLNGFQCICLPGFSGT 546
CL D+ H L P L E L E E C PC++ C DL F+C C G
Sbjct: 579 CLQDVRVDGHLLLPEDLGENVLLGCERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGP 638
Query: 547 RCEEDIDECR----SSPCANGGQCQDQPG-----AFHCKCLPGFEGPRCQTEVDEC--LS 595
C ++I +P + Q+ PG +F + G Q D L+
Sbjct: 639 TCADEIPAATFGLGGAPSSASFLLQELPGPNLTVSFLLRTRES-AGLLLQFANDSAAGLT 697
Query: 596 DPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGS 655
G ++PG+ + P + L + + + Q + + + L D
Sbjct: 698 VFLSEGRIRAEVPGSPAVVLPGRWDDGLRHLVMLSFGPDQLQDLGQHVHVGGRLLAADSQ 757
Query: 656 P------GCAPPEDNCTCHHGH----CQRSSCVCDVGWTGPECEAELGGCISA------P 699
P GC CH SS ++G G + GC+S P
Sbjct: 758 PWGGPFRGCLQDLRLDGCHLPFFPLPLDNSSQPSELG--GRQSWNLTAGCVSEDMCSPDP 815
Query: 700 CAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYC 753
C +GGTC + ++CTCP +TGPTC++++ C PCL +C P G+ C
Sbjct: 816 CFNGGTCLVTWNDFHCTCPANFTGPTCAQQLW-CPGQPCLPPATCEEVPDGFVC 868
Score = 61.2 bits (147), Expect = 1e-08
Identities = 77/284 (27%), Positives = 100/284 (35%), Gaps = 42/284 (14%)
Query: 769 DYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSC---ADSPCRNRATCQDSP 825
+ C PC +GG+CV+ F C CA +GP C ++ + +P Q+ P
Sbjct: 607 EQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEIPAATFGLGGAPSSASFLLQELP 666
Query: 826 QGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTG------PSFHCLCLQG-WTGPL 878
GP L+ A + L G P + L G W L
Sbjct: 667 -GPNLTVSFLLRTRESAGLLLQFANDSAAGLTVFLSEGRIRAEVPGSPAVVLPGRWDDGL 725
Query: 879 CNLPLSSCQKAALSQGIDVSSLCHNGG--LCVDSGPSYFCHCPPGFQGSLCQDHVNPCE- 935
+L + S L D+ H GG L DS P F+G L ++ C
Sbjct: 726 RHLVMLSFGPDQLQ---DLGQHVHVGGRLLAADSQP-----WGGPFRGCLQDLRLDGCHL 777
Query: 936 ---SRPCQNGATCMAQPSGYLCQCAPGYDGQN----CSKELDACQSQPCHNHGTCTPKPG 988
P N + QPS G N C E D C PC N GTC
Sbjct: 778 PFFPLPLDNSS----QPSEL-----GGRQSWNLTAGCVSE-DMCSPDPCFNGGTCLVTWN 827
Query: 989 GFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYC 1032
FHC CP F G C + C QPC P T C + + F C
Sbjct: 828 DFHCTCPANFTGPTCAQQL-WCPGQPCLPPAT--CEEVPDGFVC 868
Score = 60.8 bits (146), Expect = 1e-08
Identities = 29/73 (39%), Positives = 35/73 (47%), Gaps = 2/73 (2%)
Query: 767 STDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQ 826
S D C PCFNGGTC+ F C C F GP C +L C PC ATC++ P
Sbjct: 807 SEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL--WCPGQPCLPPATCEEVPD 864
Query: 827 GPRCLCPTGYTGG 839
G C+ + G
Sbjct: 865 GFVCVAEATFREG 877
Score = 60.1 bits (144), Expect = 2e-08
Identities = 33/93 (35%), Positives = 42/93 (45%), Gaps = 4/93 (4%)
Query: 709 QPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTST 768
QPS T SE+M C PC NGG+C + ++CTCP + TGP C
Sbjct: 789 QPSELGGRQSWNLTAGCVSEDM--CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL 846
Query: 769 DYCVSAPCFNGGTCVNRPGTFSCLCAMGF-QGP 800
+C PC TC P F C+ F +GP
Sbjct: 847 -WCPGQPCLPPATCEEVPDGFVCVAEATFREGP 878
Score = 59.7 bits (143), Expect = 3e-08
Identities = 77/327 (23%), Positives = 104/327 (31%), Gaps = 42/327 (12%)
Query: 689 EAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSP 748
+A GC+ G P+ G N E C PC++GGSC
Sbjct: 573 DATFAGCLQDVRVDGHLLLPEDLGENVLLGC--------ERREQCRPLPCVHGGSCVDLW 624
Query: 749 GGYYCTCPPSHTGPQCQ----TSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEG 804
+ C C H GP C +T AP PG + + + G
Sbjct: 625 THFRCDCARPHRGPTCADEIPAATFGLGGAPSSASFLLQELPGP-NLTVSFLLRTRESAG 683
Query: 805 KLRPSCADSPC---------RNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPR 855
L DS R RA + P P + P + G +M
Sbjct: 684 LLLQFANDSAAGLTVFLSEGRIRA---EVPGSPAVVLPGRWDDGLRHLVMLSFGPDQLQD 740
Query: 856 NSHCLQTGPSFHCLCLQGWTGP----LCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSG 911
+ G Q W GP L +L L C +D SS G
Sbjct: 741 LGQHVHVGGRLLAADSQPWGGPFRGCLQDLRLDGCHLPFFPLPLDNSSQPSELG----GR 796
Query: 912 PSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDA 971
S+ G + +D C PC NG TC+ + + C C + G C+++L
Sbjct: 797 QSWNLTA-----GCVSEDM---CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-W 847
Query: 972 CQSQPCHNHGTCTPKPGGFHCACPPGF 998
C QPC TC P GF C F
Sbjct: 848 CPGQPCLPPATCEEVPDGFVCVAEATF 874
Score = 55.5 bits (132), Expect = 5e-07
Identities = 25/67 (37%), Positives = 32/67 (47%), Gaps = 1/67 (1%)
Query: 553 DECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFF 612
D C PC NGG C FHC C F GP C ++ C PC A+C ++P F
Sbjct: 809 DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFV 867
Query: 613 CLCPSGF 619
C+ + F
Sbjct: 868 CVAEATF 874
Score = 55.5 bits (132), Expect = 5e-07
Identities = 25/58 (43%), Positives = 33/58 (56%), Gaps = 1/58 (1%)
Query: 443 PSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCL 500
P PC +GG+CL T F+C CP +TG C A C QPC P +TC ++ F C+
Sbjct: 813 PDPCFNGGTCLVTWNDFHCTCPANFTGPTC-AQQLWCPGQPCLPPATCEEVPDGFVCV 869
Score = 55.1 bits (131), Expect = 7e-07
Identities = 28/78 (35%), Positives = 35/78 (44%), Gaps = 6/78 (7%)
Query: 154 CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPG-PCPKGTSCH 212
C D CS +PC NGG CL T+ C CP F G C + + PG PC +C
Sbjct: 805 CVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL----WCPGQPCLPPATCE 860
Query: 213 NTLGSFQCLCPVG-QEGP 229
F C+ +EGP
Sbjct: 861 EVPDGFVCVAEATFREGP 878
Score = 52.4 bits (124), Expect = 4e-06
Identities = 23/60 (38%), Positives = 28/60 (46%), Gaps = 1/60 (1%)
Query: 479 CLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCI 538
C PC G TCL FHC CP G C + C PCL A C ++ +GF C+
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHCTCPANFTGPTC-AQQLWCPGQPCLPPATCEEVPDGFVCV 869
Score = 49.7 bits (117), Expect = 3e-05
Identities = 81/293 (27%), Positives = 102/293 (34%), Gaps = 47/293 (16%)
Query: 32 PEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLP 91
P PC +GG+C+ L C CA G TC P L GG+ + A L
Sbjct: 611 PLPCVHGGSCVDLWT-HFRCDCARPHRGPTCADEIPAATFGL---GGAPSS---ASFLLQ 663
Query: 92 SSPSP-LTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWT 150
P P LT SFL G Q + + GR + G P +PG
Sbjct: 664 ELPGPNLTVSFLLRTRES-AGLLLQFANDSAAGLTVFLSEGRIRAEVPGSPAV-VLPGRW 721
Query: 151 GEQCQLRDFCSANP---------CVNGGVCLATYPQIQCHCPPGFEGHACERDV--NECF 199
+ + S P GG LA Q P G C +D+ + C
Sbjct: 722 DDGLRHLVMLSFGPDQLQDLGQHVHVGGRLLAADSQ-----PWGGPFRGCLQDLRLDGCH 776
Query: 200 QDPGPCPKGTSCH-NTLGSFQCLCPVGQEGPRCELRAG-----PCPPRGCSNGGTCQLMP 253
P P S + LG Q L AG C P C NGGTC L+
Sbjct: 777 LPFFPLPLDNSSQPSELGGRQSW----------NLTAGCVSEDMCSPDPCFNGGTC-LVT 825
Query: 254 EKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETW 306
D FH C CP F GP C C C TC++ D + C+ T+
Sbjct: 826 WND--FH-CTCPANFTGPTC-AQQLWCPGQPCLPPATCEEVPDGFVCVAEATF 874
Score = 47.0 bits (110), Expect = 2e-04
Identities = 25/66 (37%), Positives = 31/66 (46%), Gaps = 2/66 (3%)
Query: 586 CQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPL-CAPNLCQPKQICKDQK 644
C +E D C DPC G +CL F C CP+ FTG C L C C P C++
Sbjct: 805 CVSE-DMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLPPATCEEVP 863
Query: 645 DKANCL 650
D C+
Sbjct: 864 DGFVCV 869
Score = 47.0 bits (110), Expect = 2e-04
Identities = 24/74 (32%), Positives = 31/74 (41%), Gaps = 2/74 (2%)
Query: 512 VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPG 571
V + C+ PC N C N F C C F+G C + + C PC C++ P
Sbjct: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPD 864
Query: 572 AFHCKCLPGF-EGP 584
F C F EGP
Sbjct: 865 GFVCVAEATFREGP 878
Score = 46.2 bits (108), Expect = 3e-04
Identities = 21/58 (36%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Query: 323 PPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCL 380
P C NGGTC + FHC C + + G +C + L C C P +TC + F C+
Sbjct: 813 PDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCV 869
Score = 45.4 bits (106), Expect = 5e-04
Identities = 32/87 (36%), Positives = 37/87 (42%), Gaps = 10/87 (11%)
Query: 1008 DECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGS 1067
D C PC GT C N F+C C TG C ++ C QPC TCE
Sbjct: 809 DMCSPDPCFNGGT--CLVTWNDFHCTCPANFTGPTCAQQLW-CPGQPCLPPATCEEV--- 862
Query: 1068 PLGFICHCPKGF-EGPTCS---HRAPS 1090
P GF+C F EGP + H A S
Sbjct: 863 PDGFVCVAEATFREGPPAAFSGHNASS 889
Score = 45.1 bits (105), Expect = 7e-04
Identities = 20/43 (46%), Positives = 23/43 (53%), Gaps = 3/43 (6%)
Query: 1045 VEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHR 1087
V D C PCF+GGTC T F C CP F GPTC+ +
Sbjct: 806 VSEDMCSPDPCFNGGTCLVTWND---FHCTCPANFTGPTCAQQ 845
Score = 42.4 bits (98), Expect = 0.005
Identities = 22/65 (33%), Positives = 26/65 (40%)
Query: 347 WGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQ 406
W T+ + D C C G TC+ F C CP TG C + C QPC A
Sbjct: 799 WNLTAGCVSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQQLWCPGQPCLPPAT 858
Query: 407 CSTNP 411
C P
Sbjct: 859 CEEVP 863
Score = 42.0 bits (97), Expect = 0.006
Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 4/68 (5%)
Query: 275 VNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQN 334
V+ D C C NGGTC + + C CP +TG C++ + G P C TC+
Sbjct: 806 VSEDMCSPDPCFNGGTCLVTWNDFHCTCPANFTGPTCAQ---QLWCPGQP-CLPPATCEE 861
Query: 335 SAGSFHCV 342
F CV
Sbjct: 862 VPDGFVCV 869
Score = 38.9 bits (89), Expect = 0.051
Identities = 36/122 (29%), Positives = 47/122 (38%), Gaps = 14/122 (11%)
Query: 627 PLCAPNLCQPKQICKDQKDK--ANCLCPDGSPGCAPPEDNCTCHHGHCQRS----SCVCD 680
PL N QP ++ Q A C+ D C+P D C + G C + C C
Sbjct: 781 PLPLDNSSQPSELGGRQSWNLTAGCVSEDM---CSP--DPCF-NGGTCLVTWNDFHCTCP 834
Query: 681 VGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGY-TGPTCSEEMTACHSGPCL 739
+TGP C +L C PC TC P G+ C + GP + SG L
Sbjct: 835 ANFTGPTCAQQL-WCPGQPCLPPATCEEVPDGFVCVAEATFREGPPAAFSGHNASSGRLL 893
Query: 740 NG 741
G
Sbjct: 894 GG 895
Score = 38.5 bits (88), Expect = 0.067
Identities = 22/73 (30%), Positives = 26/73 (35%), Gaps = 8/73 (10%)
Query: 390 CHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHG 449
C EDMC PC C C C ++GPTC Q L PC
Sbjct: 805 CVSEDMCSPDPCFNGGTCLVT--WNDFHCTCPANFTGPTCAQQL------WCPGQPCLPP 856
Query: 450 GSCLNTPGSFNCL 462
+C P F C+
Sbjct: 857 ATCEEVPDGFVCV 869
Score = 37.7 bits (86), Expect = 0.11
Identities = 16/57 (28%), Positives = 24/57 (42%)
Query: 154 CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTS 210
C+ R+ C PCV+GG C+ + +C C G C ++ G P S
Sbjct: 603 CERREQCRPLPCVHGGSCVDLWTHFRCDCARPHRGPTCADEIPAATFGLGGAPSSAS 659
Score = 37.0 bits (84), Expect = 0.19
Identities = 16/46 (34%), Positives = 21/46 (45%), Gaps = 3/46 (6%)
Query: 1048 DPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGF 1093
+ C PC HGG+C F C C + GPTC+ P+ F
Sbjct: 607 EQCRPLPCVHGGSC---VDLWTHFRCDCARPHRGPTCADEIPAATF 649
Score = 36.2 bits (82), Expect = 0.33
Identities = 30/110 (27%), Positives = 38/110 (34%), Gaps = 11/110 (10%)
Query: 90 LPSSPSPLTPSFLCTCLPGFTGERCQAKL--EDPCPPSFCSKRGRCHIQASGRPQCSCMP 147
LP P PL S + L G A ED C P C G C + + C+C
Sbjct: 777 LPFFPLPLDNSSQPSELGGRQSWNLTAGCVSEDMCSPDPCFNGGTCLVTWNDF-HCTCPA 835
Query: 148 GWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHC--------PPGFEGH 189
+TG C + +C PC+ C C P F GH
Sbjct: 836 NFTGPTCAQQLWCPGQPCLPPATCEEVPDGFVCVAEATFREGPPAAFSGH 885
Score = 35.8 bits (81), Expect = 0.43
Identities = 33/117 (28%), Positives = 42/117 (35%), Gaps = 25/117 (21%)
Query: 17 CVSVVRPRGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQN 76
C+ +R G FP P N L G+ + G + E PDPC N
Sbjct: 766 CLQDLRLDGCHLPFFPLPLDNSSQPSELG-GRQSWNLTAGCVSEDMCSPDPCF------N 818
Query: 77 GGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKL---EDPC-PPSFCSK 129
GG+C F CTC FTG C +L PC PP+ C +
Sbjct: 819 GGTCLV--------------TWNDFHCTCPANFTGPTCAQQLWCPGQPCLPPATCEE 861
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 285 bits (729), Expect = 3e-76
Identities = 253/883 (28%), Positives = 325/883 (36%), Gaps = 237/883 (26%)
Query: 381 CPPG--RTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLM 438
C PG +G C +C + HG +C +P T C C+PG+ GP C D
Sbjct: 88 CCPGYYESGDFCI--PLCTEECVHG--RC-VSPDT----CHCEPGWGGPDCSSGCDSDHW 138
Query: 439 AQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFH 498
+ C+ L P + C+C G+ G RCE
Sbjct: 139 GPHCSNRCQCQNGALCNPITGACVCAAGFRGWRCEE------------------------ 174
Query: 499 CLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDID----- 553
LC PG G+ C++ C + A C +C+C PG++G CEE
Sbjct: 175 -LCAPGTHGKGCQLPCQ------CRHGASCDPRAG--ECLCAPGYTGVYCEELCPPGSHG 225
Query: 554 -ECR-SSPCANGGQCQDQPGAFHCKCLPGFEGPRCQ------TEVDECLSD-PCPVGASC 604
C PC NGG C G C C PG+ G C T C D PC G C
Sbjct: 226 AHCELRCPCQNGGTCHHITG--ECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQC 283
Query: 605 LDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDN 664
+ G C C +G+ G C+ CP GS G + +
Sbjct: 284 DHVTGQ--CHCTAGYMGDRCQEE-----------------------CPFGSFGFQCSQ-H 317
Query: 665 CTCHHG-HCQRSS--CVCDVGWTGPECEAEL--------GGCISAPCAHGGTCYPQPSGY 713
C CH+G C ++ C C+ G+ GP C+ L G + PC T P
Sbjct: 318 CDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTG 377
Query: 714 NCTCPTGYTGPTCSEEMTACHSGP-------CLNGGSCNPSPGGYYCTCPPSHTGPQCQT 766
CTC G++G C+E + G C NG C+ GG CTC P G C
Sbjct: 378 ACTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNGADCHSITGG--CTCAPGFMGEVCAV 435
Query: 767 STDYCVSAP-------CFNGGTCVNRPGTFSCLCAMGFQGPRC-----EGKLRPSCADS- 813
S P C NGGTC P SC C G+QG C G +C +S
Sbjct: 436 SCAAGTYGPNCSSICSCNNGGTC--SPVDGSCTCKEGWQGLDCTLPCPSGTWGLNCNESC 493
Query: 814 PCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRN------------SHCLQ 861
C N A C SP C C G+ G +C+ PCP SH
Sbjct: 494 TCANGAAC--SPIDGSCSCTPGWLGDTCEL--------PCPDGTFGLNCSEHCDCSHADG 543
Query: 862 TGP-SFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPP 920
P + HC CL GWTG C+ S+C VS C NGG C S C C P
Sbjct: 544 CDPVTGHCCCLAGWTGIRCD---STCPPGRWGPNCSVSCSCENGGSCSPEDGS--CECAP 598
Query: 921 GFQGSLCQ----------DHVNPC-----ESRPCQNGA---TCMAQPSGYLCQ--CAPGY 960
GF+G LCQ PC SRPC + + C+ SG LC CA GY
Sbjct: 599 GFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGY 658
Query: 961 DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGT 1020
GQ+C+ Q C N+GTC+P G C C PG++G C
Sbjct: 659 FGQDCA------QLCSCANNGTCSPIDGS--CQCFPGWIGKDCSQ--------------- 695
Query: 1021 AACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFE 1080
C PG G C H+ C +G +C A G+ CHC G+
Sbjct: 696 ------------ACPPGFWGPAC------FHACSCHNGASCSAEDGA-----CHCTPGWT 732
Query: 1081 GPTCSHRAPSCGFH-------HCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPK- 1132
G C+ R P+ F C +G C +C C +G+ G C AP
Sbjct: 733 GLFCTQRCPAAFFGKDCGRVCQCQNGASC-----DHISGKCTCRTGFTGQHCEQRCAPGT 787
Query: 1133 ---GCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQK 1172
GC C+ N +C TG C C G RC +
Sbjct: 788 FGYGCQQLCECMNNSTCDHVTG------TCYCSPGFKGIRCDQ 824
Score = 284 bits (727), Expect = 5e-76
Identities = 255/837 (30%), Positives = 313/837 (37%), Gaps = 225/837 (26%)
Query: 262 CLCPPGFIGPDCEVNPD------NCVSH-QCQNGGTCQDGLDTYTCLCPETWTGWDCSED 314
C C PG+ GPDC D +C + QCQNG C T C+C + GW C E+
Sbjct: 118 CHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNP--ITGACVCAAGFRGWRC-EE 174
Query: 315 VDECETQG-----PPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEE------NLDDC-IAA 362
+ T G P CR+G +C AG C+C G+ G CEE + C +
Sbjct: 175 LCAPGTHGKGCQLPCQCRHGASCDPRAG--ECLCAPGYTGVYCEELCPPGSHGAHCELRC 232
Query: 363 TCAPGSTCIDRVGSFSCLCPPGRTGLLCHL--------EDMCLSQPCHGDAQCSTNPLTG 414
C G TC G C CPPG TG +C ++ PCH QC + +TG
Sbjct: 233 PCQNGGTCHHITG--ECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQC--DHVTG 288
Query: 415 STLCLCQPGYSGPTCHQDLDECLMAQQG-----PSPCEHGGSCLNTPGSFNCLCPPGYTG 469
C C GY G C +EC G C +GG C T G+ C C PGY G
Sbjct: 289 Q--CHCTAGYMGDRCQ---EECPFGSFGFQCSQHCDCHNGGQCSPTTGA--CECEPGYKG 341
Query: 470 SRC------EADHNECLSQP----------CHP---GSTCLDLLATFHC--LCPPGLEGQ 508
RC E H + P CHP TC + HC CP G G
Sbjct: 342 PRCQERLCPEGLHGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGD 401
Query: 509 LCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDI------DECRS-SPCA 561
C++ C N ADCH + G C C PGF G C C S C
Sbjct: 402 GCQL------PCTCQNGADCHSITGG--CTCAPGFMGEVCAVSCAAGTYGPNCSSICSCN 453
Query: 562 NGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECL-------SDPCPVGASCLDLPGAFFCL 614
NGG C G+ C C G++G C S C GA+C + G+ C
Sbjct: 454 NGGTCSPVDGS--CTCKEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDGS--CS 509
Query: 615 CPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGH-CQ 673
C G+ G CE+P CPDG+ G E +C C H C
Sbjct: 510 CTPGWLGDTCELP-----------------------CPDGTFGLNCSE-HCDCSHADGCD 545
Query: 674 --RSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMT 731
C C GWTG C++ TCP G GP CS
Sbjct: 546 PVTGHCCCLAGWTGIRCDS-------------------------TCPPGRWGPNCSV--- 577
Query: 732 ACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSC 791
S C NGGSC+P G C C P GP CQ
Sbjct: 578 ---SCSCENGGSCSPEDGS--CECAPGFRGPLCQR------------------------- 607
Query: 792 LCAMGFQGPRCEGKLRPSCADS--PCRN-RATCQDSP--QGPRC--LCPTGYTGGSCQTL 844
+C GF G C + P C S PC + C+ P G C +C GY G C
Sbjct: 608 ICPPGFYGHGC-AQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDC--- 663
Query: 845 MDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNG 904
LC+ C N C S C C GW G C+ +C + CHNG
Sbjct: 664 AQLCS---CANNGTCSPIDGS--CQCFPGWIGKDCS---QACPPGFWGPACFHACSCHNG 715
Query: 905 GLCVDSGPSYFCHCPPGFQGSLC----------QDHVNPCESRPCQNGATCMAQPSGYLC 954
C S CHC PG+ G C +D C+ CQNGA+C SG C
Sbjct: 716 ASC--SAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQ---CQNGASC-DHISG-KC 768
Query: 955 QCAPGYDGQNCSKELD------ACQSQ-PCHNHGTCTPKPGGFHCACPPGFVGLRCE 1004
C G+ GQ+C + CQ C N+ TC G C C PGF G+RC+
Sbjct: 769 TCRTGFTGQHCEQRCAPGTFGYGCQQLCECMNNSTCDHVTG--TCYCSPGFKGIRCD 823
Score = 248 bits (633), Expect = 4e-65
Identities = 232/764 (30%), Positives = 288/764 (37%), Gaps = 197/764 (25%)
Query: 35 CANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLC---QNGGSCQALLPAPLGLP 91
C NG C ++ G C CA GF G C+ +LC +G CQ LP
Sbjct: 148 CQNGALCNPIT---GACVCAAGFRGWRCE--------ELCAPGTHGKGCQ--LPCQCRHG 194
Query: 92 SSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSF----------CSKRGRCHIQASGRP 141
+S P C C PG+TG C E+ CPP C G CH +G
Sbjct: 195 ASCDPRAGE--CLCAPGYTGVYC----EELCPPGSHGAHCELRCPCQNGGTCH-HITG-- 245
Query: 142 QCSCMPGWTGEQC-------QLRDFCSAN-PCVNGGVCLATYPQIQCHCPPGFEGHACER 193
+C+C PGWTG C CS + PC +GG C + QCHC G+ G C+
Sbjct: 246 ECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQC--DHVTGQCHCTAGYMGDRCQE 303
Query: 194 DVN------ECFQDPGPCPKGTSCHNTLGSFQC------------LCPVGQEGPRCELRA 235
+ +C Q C G C T G+ +C LCP G GP C L
Sbjct: 304 ECPFGSFGFQCSQH-CDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHGPGCTL-- 360
Query: 236 GPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDC-EVNPDNCVSHQCQNGGTCQDG 294
PCP C T P + C C PG+ G C E P CQ TCQ+G
Sbjct: 361 -PCP---CDADNTISCHPVTGA----CTCQPGWSGHHCNESCPVGYYGDGCQLPCTCQNG 412
Query: 295 LDTYT----CLCPETWTGWDCSEDVDECETQGPP-----HCRNGGTCQNSAGSFHCVCVS 345
D ++ C C + G C+ T GP C NGGTC GS C C
Sbjct: 413 ADCHSITGGCTCAPGFMGEVCAVSC-AAGTYGPNCSSICSCNNGGTCSPVDGS--CTCKE 469
Query: 346 GWGGTSC-------EENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHL--EDMC 396
GW G C L+ + TCA G+ C G SC C PG G C L D
Sbjct: 470 GWQGLDCTLPCPSGTWGLNCNESCTCANGAACSPIDG--SCSCTPGWLGDTCELPCPDGT 527
Query: 397 LSQPCHGDAQCS----TNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPS-----PCE 447
C CS +P+TG C C G++G C C + GP+ CE
Sbjct: 528 FGLNCSEHCDCSHADGCDPVTGH--CCCLAGWTGIRCD---STCPPGRWGPNCSVSCSCE 582
Query: 448 HGGSCLNTPGSFNC-----------LCPPGYTGSRCEADHNECL--SQPCHPGSTCLDLL 494
+GGSC GS C +CPPG+ G C C+ S+PCH S
Sbjct: 583 NGGSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGI---- 638
Query: 495 ATFHCLCPPGLEGQLCEVET------NECAS-APCLNHADCHDLLNGFQCI--------- 538
C C PG G LC +CA C N+ C + QC
Sbjct: 639 ----CECLPGFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCS 694
Query: 539 --CLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSD 596
C PGF G C + C NG C + GA C C PG+ G C
Sbjct: 695 QACPPGFWGPAC------FHACSCHNGASCSAEDGA--CHCTPGWTGLFCTQRCPAAFFG 746
Query: 597 -------PCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNL----CQPKQICKDQKD 645
C GASC + G C C +GFTGQ CE CAP CQ Q+C+
Sbjct: 747 KDCGRVCQCQNGASCDHISGK--CTCRTGFTGQHCE-QRCAPGTFGYGCQ--QLCE---- 797
Query: 646 KANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECE 689
C+ +N TC H +C C G+ G C+
Sbjct: 798 ---CM------------NNSTCDH---VTGTCYCSPGFKGIRCD 823
Score = 235 bits (599), Expect = 4e-61
Identities = 252/868 (29%), Positives = 310/868 (35%), Gaps = 247/868 (28%)
Query: 528 CHDLLNGFQCI-----------------------CLPGF--SGTRCEE-DIDECRSSPCA 561
C D+LN F+C C PG+ SG C +EC C
Sbjct: 54 CTDILNWFKCTRHRISYKTAYRRGLRTMYRRRSQCCPGYYESGDFCIPLCTEECVHGRCV 113
Query: 562 NGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDP-------CPVGASCLDLPGAFFCL 614
+ C HC+ PG+ GP C + D P C GA C + GA C+
Sbjct: 114 SPDTC-------HCE--PGWGGPDCSSGCDSDHWGPHCSNRCQCQNGALCNPITGA--CV 162
Query: 615 CPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGH--- 671
C +GF G CE LC P K + C C G+ C P C C G+
Sbjct: 163 CAAGFRGWRCE------ELCAPGTHGKGCQ--LPCQCRHGA-SCDPRAGECLCAPGYTGV 213
Query: 672 -CQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEM 730
C+ +C G G CE + PC +GGTC+ C CP G+TG C++
Sbjct: 214 YCEE---LCPPGSHGAHCE------LRCPCQNGGTCHHITG--ECACPPGWTGAVCAQPC 262
Query: 731 TACHSG-------PCLNGGSCNPSPGGYYCT-----------CPPSHTGPQCQTSTDYCV 772
G PC +GG C+ G +CT CP G QC D
Sbjct: 263 PPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCSQHCD--- 319
Query: 773 SAPCFNGGTCVNRPGTFSCLCAMGFQGPRC------EGKLRPSC-------ADS-----P 814
C NGG C P T +C C G++GPRC EG P C AD+ P
Sbjct: 320 ---CHNGGQC--SPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPCPCDADNTISCHP 374
Query: 815 CRNRATCQDSPQGPRC--LCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFH----- 867
TCQ G C CP GY G CQ PC Q G H
Sbjct: 375 VTGACTCQPGWSGHHCNESCPVGYYGDGCQL--------PCT-----CQNGADCHSITGG 421
Query: 868 CLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLC--HNGGLCVDSGPSYFCHCPPGFQGS 925
C C G+ G +C + SC AA + G + SS+C +NGG C S C C G+QG
Sbjct: 422 CTCAPGFMGEVCAV---SC--AAGTYGPNCSSICSCNNGGTCSPVDGS--CTCKEGWQGL 474
Query: 926 LCQDHVNPC----------ESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKE------- 968
C PC ES C NGA C P C C PG+ G C
Sbjct: 475 DC---TLPCPSGTWGLNCNESCTCANGAAC--SPIDGSCSCTPGWLGDTCELPCPDGTFG 529
Query: 969 LDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLAN 1028
L+ + C + C P G HC C G+ G+RC+
Sbjct: 530 LNCSEHCDCSHADGCDPVTG--HCCCLAGWTGIRCDST---------------------- 565
Query: 1029 AFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRA 1088
C PG G C V S C +GG+C GS C C GF GP C
Sbjct: 566 -----CPPGRWGPNCSV------SCSCENGGSCSPEDGS-----CECAPGFRGPLCQRIC 609
Query: 1089 PSCGF--HHCHHG-GLCLPSPKP--GFPPRCACLSGYGGPDCLTPPA----PKGCGPPSP 1139
P GF H C LC+ S +P C CL G+ G C A + C
Sbjct: 610 PP-GFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDCAQLCS 668
Query: 1140 CLYNGSCSETTGL-----GGPGFRCS--CPHSSPGPRCQKPGAKGCEGRSGDGACDAGCS 1192
C NG+CS G G G CS CP GP C C +G A CS
Sbjct: 669 CANNGTCSPIDGSCQCFPGWIGKDCSQACPPGFWGPAC----FHACSCHNG-----ASCS 719
Query: 1193 GPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCE-TPPAC 1251
G C+ G W G RC F C C + +G C+ C
Sbjct: 720 AEDG---ACHCTPG----WTGLFCTQRCPAAFFGKDCGRVCQCQ----NGASCDHISGKC 768
Query: 1252 TPAYDQYCHDHFHNGHCEKGCNTAECGW 1279
T C F HCE+ C G+
Sbjct: 769 T------CRTGFTGQHCEQRCAPGTFGY 790
Score = 218 bits (554), Expect = 6e-56
Identities = 198/674 (29%), Positives = 242/674 (35%), Gaps = 151/674 (22%)
Query: 717 CPTGYTG-----PTCSEEMTACHSGPCLNGGSCNPSPG--GYYCT--CPPSHTGPQCQTS 767
CP Y P C+EE C G C++ +C+ PG G C+ C H GP C
Sbjct: 89 CPGYYESGDFCIPLCTEE---CVHGRCVSPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNR 145
Query: 768 TDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSC----ADSPCRNRATCQD 823
C NG C P T +C+CA GF+G RCE P PC+ R
Sbjct: 146 CQ------CQNGALC--NPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASC 197
Query: 824 SPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSH---------CLQTGPSFH----CLC 870
P+ CLC GYTG C+ L CP SH C G H C C
Sbjct: 198 DPRAGECLCAPGYTGVYCEEL--------CPPGSHGAHCELRCPCQNGGTCHHITGECAC 249
Query: 871 LQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDH 930
GWTG +C P C Q CH+GG C + CHC G+ G CQ+
Sbjct: 250 PPGWTGAVCAQP---CPPGTFGQNCSQDCPCHHGGQC--DHVTGQCHCTAGYMGDRCQEE 304
Query: 931 VN------PCESR-PCQNGATCMAQPSGYLCQCAPGYDGQNCSKEL-------------- 969
C C NG C P+ C+C PGY G C + L
Sbjct: 305 CPFGSFGFQCSQHCDCHNGGQC--SPTTGACECEPGYKGPRCQERLCPEGLHGPGCTLPC 362
Query: 970 --DACQSQPCHN-HGTCTPKPG--GFHC--ACPPGFVGLRCEGDVDECLDQPCHPTGTAA 1022
DA + CH G CT +PG G HC +CP G+ G C+ PC A
Sbjct: 363 PCDADNTISCHPVTGACTCQPGWSGHHCNESCPVGYYGDGCQ--------LPCTCQNGAD 414
Query: 1023 CHSLANAFYCQCLPGHTGQWCEVEIDPCHSQP-------CFHGGTCEATAGSPLGFICHC 1075
CHS+ C C PG G+ C V P C +GGTC GS C C
Sbjct: 415 CHSITGG--CTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVDGS-----CTC 467
Query: 1076 PKGFEGPTCSHRAPSCGFH-------HCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTP 1128
+G++G C+ PS + C +G C P C+C G+ G C P
Sbjct: 468 KEGWQGLDCTLPCPSGTWGLNCNESCTCANGAACSP-----IDGSCSCTPGWLGDTCELP 522
Query: 1129 PAPKG-----CGPPSPCLYNGSCSETTG-----LGGPGFRC--SCPHSSPGPRCQKP--- 1173
P G C C + C TG G G RC +CP GP C
Sbjct: 523 -CPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSC 581
Query: 1174 -GAKGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQ-CHP 1231
C G C G GP C P + G C L + CH
Sbjct: 582 ENGGSCSPEDGSCECAPGFRGPL-------CQRICPPGFYGHGCAQPCPLCVHSSRPCHH 634
Query: 1232 QCDSEECL--FDGYDCETPPACTPAY-----DQYCHDHFHNGHCEKGCNTAEC--GWDGG 1282
ECL F G C C Y Q C +NG C + +C GW G
Sbjct: 635 ISGICECLPGFSGALCNQ--VCAGGYFGQDCAQLC-SCANNGTCSPIDGSCQCFPGWIGK 691
Query: 1283 DCRPEDGDPEWGPS 1296
DC WGP+
Sbjct: 692 DCSQACPPGFWGPA 705
Score = 151 bits (381), Expect = 7e-36
Identities = 141/472 (29%), Positives = 178/472 (37%), Gaps = 125/472 (26%)
Query: 32 PEPCANGGTCLSLSLGQGTCQCAPGFLGETC-------QFPDPCQNAQLCQNGGSCQALL 84
P C NG C S++ G C CAPGF+GE C + C + C NGG+C
Sbjct: 406 PCTCQNGADCHSIT---GGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTC---- 458
Query: 85 PAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSF----CSKRGRCHIQASGR 140
SP+ S CTC G+ G C PCP C++ C A+
Sbjct: 459 ----------SPVDGS--CTCKEGWQGLDCTL----PCPSGTWGLNCNESCTCANGAACS 502
Query: 141 P---QCSCMPGWTGEQCQL-----------RDFC------SANPCVNGGVCLATYPQIQC 180
P CSC PGW G+ C+L + C +P CLA + I+C
Sbjct: 503 PIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHADGCDPVTGHCCCLAGWTGIRC 562
Query: 181 H--CPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQC-----------LCPVGQE 227
CPPG G C + C G SC GS +C +CP G
Sbjct: 563 DSTCPPGRWGPNCSVSCS--------CENGGSCSPEDGSCECAPGFRGPLCQRICPPGFY 614
Query: 228 GPRCELRAGPCP-----PRGCSN-GGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCV 281
G C A PCP R C + G C+ +P +C G+ G DC C
Sbjct: 615 GHGC---AQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGGYFGQDC---AQLC- 667
Query: 282 SHQCQNGGTCQ--DGLDTYTCLCPETWTGWDCSEDVDECETQGPP-----HCRNGGTCQN 334
C N GTC DG +C C W G DCS+ GP C NG +C
Sbjct: 668 --SCANNGTCSPIDG----SCQCFPGWIGKDCSQACPP-GFWGPACFHACSCHNGASCSA 720
Query: 335 SAGSFHCVCVSGWGGTSCEENL------DDC-IAATCAPGSTCIDRVGSFSCLCPPGRTG 387
G+ C C GW G C + DC C G++C D + S C C G TG
Sbjct: 721 EDGA--CHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGASC-DHI-SGKCTCRTGFTG 776
Query: 388 LLCHLEDMC----LSQPCHGDAQCSTNP----LTGSTLCLCQPGYSGPTCHQ 431
H E C C +C N +TG+ C C PG+ G C Q
Sbjct: 777 Q--HCEQRCAPGTFGYGCQQLCECMNNSTCDHVTGT--CYCSPGFKGIRCDQ 824
Score = 144 bits (364), Expect = 7e-34
Identities = 144/492 (29%), Positives = 179/492 (36%), Gaps = 92/492 (18%)
Query: 868 CLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLC 927
C C GW GP C+ S C C NG LC + + C C GF+G C
Sbjct: 118 CHCEPGWGGPDCS---SGCDSDHWGPHCSNRCQCQNGALC--NPITGACVCAAGFRGWRC 172
Query: 928 QD------HVNPCESRPCQ--NGATCMAQPSGYLCQCAPGYDGQNCSKELDA------CQ 973
++ H C+ PCQ +GA+C P C CAPGY G C + C+
Sbjct: 173 EELCAPGTHGKGCQL-PCQCRHGASC--DPRAGECLCAPGYTGVYCEELCPPGSHGAHCE 229
Query: 974 SQ-PCHNHGTCTPKPGGFHCACPPGFVGLRCEGDV------DECL-DQPCHPTGTAACHS 1025
+ PC N GTC G CACPPG+ G C C D PCH G C
Sbjct: 230 LRCPCQNGGTCHHITG--ECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQ--CDH 285
Query: 1026 LANAFYCQCLPGHTGQWCEVEID------PCHSQ-PCFHGGTCEATAGSPLGFICHCPKG 1078
+ C C G+ G C+ E C C +GG C T G+ C C G
Sbjct: 286 VTGQ--CHCTAGYMGDRCQEECPFGSFGFQCSQHCDCHNGGQCSPTTGA-----CECEPG 338
Query: 1079 FEGPTCSHRAPSCGFHHCHHGGLCLPSPKPG--------FPPRCACLSGYGGPDCLTPPA 1130
++GP C R G H G LP P C C G+ G C
Sbjct: 339 YKGPRCQERLCPEGL---HGPGCTLPCPCDADNTISCHPVTGACTCQPGWSGHHC-NESC 394
Query: 1131 P-----KGCGPPSPCLYNGSCSETTG--LGGPGF-----RCSCPHSSPGPRCQKPGAKGC 1178
P GC P C C TG PGF SC + GP C + C
Sbjct: 395 PVGYYGDGCQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNC----SSIC 450
Query: 1179 EGRSGDGAC---DAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDS 1235
+G G C D C+ G W G DC+L P G + C C P S
Sbjct: 451 SCNNG-GTCSPVDGSCTCKEG-WQGLDCTLPCPSGTWGLNCNESC-TCANGAACSPIDGS 507
Query: 1236 EECL--FDGYDCETPPACTPAYDQYCHDHFHNGHCEKGCN--TAEC----GWDGGDCRPE 1287
C + G CE P + C +H H + GC+ T C GW G C
Sbjct: 508 CSCTPGWLGDTCEL-PCPDGTFGLNCSEHCDCSHAD-GCDPVTGHCCCLAGWTGIRCDST 565
Query: 1288 DGDPEWGPSLAL 1299
WGP+ ++
Sbjct: 566 CPPGRWGPNCSV 577
>gi|110347437 latent transforming growth factor beta binding protein 4
isoform c [Homo sapiens]
Length = 1557
Score = 268 bits (685), Expect = 4e-71
Identities = 312/1108 (28%), Positives = 410/1108 (37%), Gaps = 270/1108 (24%)
Query: 306 WTGWDCSEDVDECET-QGPPHCRNGGTCQNSAGSFHCVCVSGWG----GTSCEENLDDC- 359
WTG + E Q P G C + + C C SG+ GT C + +D+C
Sbjct: 467 WTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCID-VDECR 525
Query: 360 -IAATCAPGSTCIDRVGSFSCLCPPG-RTG---LLCHLEDMCLSQPCHGD-AQCSTNPLT 413
+ CAPG C + GSF C+C PG R G C D C P D +C P
Sbjct: 526 RVPPPCAPGR-CENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTP-- 582
Query: 414 GSTLCLCQPGYS----GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTG 469
GS LC+C GY G +C QD+DEC Q P C G +C N PGSF C+CP G+ G
Sbjct: 583 GSFLCVCPAGYQAAPHGASC-QDVDECT---QSPGLCGRG-ACKNLPGSFRCVCPAGFRG 637
Query: 470 SRCEADHNECLSQP--CHPGSTCLDLLATFHCLCPPGLE----GQLCEVETNECA-SAPC 522
S CE D +EC +P C PG C + +FHC CP G G C+ + +ECA S P
Sbjct: 638 SACEEDVDECAQEPPPCGPGR-CDNTAGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPP 695
Query: 523 LNHADCHDLLNGFQCICLPGF----SGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCL 578
+ C + FQC+C GF +G+ CE D+DEC + G +C + PG+F C+
Sbjct: 696 CTYGRCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTC 754
Query: 579 PG---FEGPRCQTEVDECLSD--PCPVGASCLDLPGAFFCLC------PSGFTGQLCEVP 627
P RC T+VDEC S PC C + G+F C C PSG G +V
Sbjct: 755 PSGHHLHRGRC-TDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVN 813
Query: 628 LCAP-NLCQPKQICKDQKDKANCLCPDG-SPGCAPPE----DNCT----CHHGHCQRSS- 676
C + C P C + C C G PG D C+ C G C +
Sbjct: 814 ECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDG 873
Query: 677 ---CVCDVGW-TGPECEAELGGCISAP-CAHGGT-------CYPQPSGYNCT--CPTGY- 721
C+C G GP+ L C+ C G C P Y C C GY
Sbjct: 874 SFECICPPGHRAGPD----LASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYH 929
Query: 722 TGP--TCSEEMTACHSGPCLNGGS-CNPSPGGYYCT--CPPSHT---GPQCQTSTDYCVS 773
GP TC + GP + G C +PG Y CT C P + G CQ +
Sbjct: 930 AGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNR 989
Query: 774 APCFNGGTCVNRPGTFSCLCAMGFQGPR----------CEGKLRPSCADSPCRN-----R 818
+ C C N PG+F CLC G++G R CE L+ C + C N
Sbjct: 990 SFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECE-TLQGVCGAALCENVEGSFL 1048
Query: 819 ATCQDSPQG-----PRCLCPTGYTGG---------SCQTLMDLCAQKPCPRNSHCLQTGP 864
C +SP+ RC+ P G + L P PR + GP
Sbjct: 1049 CVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGP 1108
Query: 865 SF---------------------------HCLCL--QGWTGPLCNLPLSSCQKAALSQGI 895
C C +GW G C + Q+ ++
Sbjct: 1109 VGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGW-GSGCRI-----QQCPGTETA 1162
Query: 896 DVSSLC-HNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCE---SRPCQNGATCMAQPSG 951
+ SLC H G SG SL +D V+ C+ + C++G C+ G
Sbjct: 1163 EYQSLCPHGRGYLAPSGDL-----------SLRRD-VDECQLFRDQVCKSGV-CVNTAPG 1209
Query: 952 YLCQCAPGY----------DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFV-- 999
Y C C+ GY D C+ E AC+ G C G +HC C P V
Sbjct: 1210 YSCYCSNGYYYHTQRLECIDNDECADEEPACEG------GRCVNTVGSYHCTCEPPLVLD 1263
Query: 1000 --GLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQP--- 1054
RC + + LD N C W EV D S P
Sbjct: 1264 GSQRRCVSNESQSLDD--------------NLGVC---------WQEVGADLVCSHPRLD 1300
Query: 1055 ---------CFHG-------GTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHH 1098
C +G C A +C+ P S P GF +
Sbjct: 1301 RQATYTECCCLYGEAWGMDCALCPAQDSDDFEALCNV---LRPPAYSPPRPG-GFGLPYE 1356
Query: 1099 GGLCLPSPKPGFPPRCACLSGYGGPDCLTPPA-PKGCGPPSPCLYNGSCSETTGLGGPGF 1157
G L P G P GP+ PPA P PP P GP
Sbjct: 1357 YGPDLGPPYQGLP---------YGPELYPPPALPYDPYPPPP--------------GPFA 1393
Query: 1158 RCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWD--GGDCSLGVPDPWKGCP 1215
R P+ + PR P + G G+ A GPG W D P+P +
Sbjct: 1394 RREAPYGA--PRFDMPDFEDDGGPYGESEAPAP-PGPGTRWPYRSRDTRRSFPEPEEPPE 1450
Query: 1216 SHSRCWLLFRDGQCHPQCDSEEC-LFDG 1242
S L + + + ++EEC + DG
Sbjct: 1451 GGSYAGSL---AEPYEELEAEECGILDG 1475
Score = 263 bits (672), Expect = 1e-69
Identities = 251/840 (29%), Positives = 337/840 (40%), Gaps = 165/840 (19%)
Query: 85 PAPLGLPSSPSPLTPSFLCTCLP--GFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQ 142
P P P P P P++ +P G + CQ P C GRC + SG
Sbjct: 451 PDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRN------PQVCGP-GRCISRPSGYT- 502
Query: 143 CSCMPGWT----GEQCQLRDFCSA--NPCVNGGVCLATYPQIQCHCPPGFEG--HACE-R 193
C+C G+ G +C D C PC G C + +C C PGF A E
Sbjct: 503 CACDSGFRLSPQGTRCIDVDECRRVPPPCAPGR-CENSPGSFRCVCGPGFRAGPRAAECL 561
Query: 194 DVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQE----GPRCELRAGPCPPRGCSNGGTC 249
DV+EC + P PC G C NT GSF C+CP G + G C+ G G C
Sbjct: 562 DVDECHRVPPPCDLGR-CENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGAC 620
Query: 250 QLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNG-GTCQDGLDTYTCLCPETWT- 307
+ +P +F C+CP GF G CE + D C G G C + ++ C CP +
Sbjct: 621 KNLP---GSFR-CVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRS 676
Query: 308 ---GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDCI 360
G C +DVDEC + PP C G C+N+ GSF CVC G+ G+ CE+ +D+C
Sbjct: 677 RGPGAPC-QDVDEC-ARSPPPCTYG-RCENTEGSFQCVCPMGFQPNTAGSECED-VDECE 732
Query: 361 AATCAPGSTCIDRVGSFSC-LCPPGRT--GLLCHLEDMCLS--QPCHGDAQCSTNPLTGS 415
PG C++ GSF C CP G C D C S PC C+ GS
Sbjct: 733 NHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTE--GS 790
Query: 416 TLCLCQPGYSGPTCHQ----DLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT--- 468
C C PGY P+ D++ECL C G CLNT GSF C C PGY
Sbjct: 791 FRCSCAPGYRAPSGRPGPCADVNECLEGDF----CFPHGECLNTDGSFACTCAPGYRPGP 846
Query: 469 -GSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPG------LEGQLCEVETNECASAP 521
G+ C D +EC + C + +F C+CPPG L L E E A
Sbjct: 847 RGASC-LDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPAL 905
Query: 522 CLNHADCHDLLNGFQCI--CLPGF----SGTRCEEDIDECRS-SPCANGGQ-CQDQPGAF 573
C + C + ++C+ C PG+ GT C+ D+DEC+ P G Q C++ PG++
Sbjct: 906 CGSQR-CENSPGSYRCVRDCDPGYHAGPEGT-CD-DVDECQEYGPEICGAQRCENTPGSY 962
Query: 574 HCK--CLPGFE---GPRCQTEVDECLSDP-CPVGASCLDLPGAFFCLCPSGFTGQLCEVP 627
C C PG++ G CQ +VDEC + C A C +LPG+F CLC G+ G
Sbjct: 963 RCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRH 1021
Query: 628 LCAPNLCQPKQ------ICKDQKDKANCLCPDG-------SPGCAPPEDNCTCHHGH--- 671
N C+ Q +C++ + C+CP+ + C PP + G
Sbjct: 1022 CVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQ 1081
Query: 672 -----------------------------CQRSSCVCDVGW------------TGPECEA 690
R C D T EC
Sbjct: 1082 APASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCC 1141
Query: 691 ELGGCISAPCAHGGTCYPQPSGYNCTCP--TGYTGPTCSEEMT------------ACHSG 736
+G + C + + Y CP GY P+ + C SG
Sbjct: 1142 TVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSG 1201
Query: 737 PCLN---GGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLC 793
C+N G SC S G YY T +C + + P GG CVN G++ C C
Sbjct: 1202 VCVNTAPGYSCYCSNGYYYHT-----QRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 1256
Score = 237 bits (604), Expect = 1e-61
Identities = 229/839 (27%), Positives = 333/839 (39%), Gaps = 193/839 (23%)
Query: 289 GTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGW- 347
G C G + C EDVDEC T G C++G C N+ G + CVC G+
Sbjct: 275 GPCPTGFERVNGSC----------EDVDECATGG--RCQHG-ECANTRGGYTCVCPDGFL 321
Query: 348 ---GGTSC------EENLDDCIAATCAPGST------------CIDRVGSF---SC-LCP 382
+SC E C G + C RVG C LCP
Sbjct: 322 LDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCP 381
Query: 383 P-GRTGLLCHLEDMCLSQPCH----GDAQCSTNPL------------------------- 412
P G G ++C + P + D + +T PL
Sbjct: 382 PFGSEGF----REICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGF 437
Query: 413 -----------------TGSTLCLCQ-PGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLN 454
G L L P ++GP + M Q+ P C G C++
Sbjct: 438 LPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPG-RCIS 496
Query: 455 TPGSFNCLCPPGYT----GSRCEADHNEC--LSQPCHPGSTCLDLLATFHCLCPPGLEG- 507
P + C C G+ G+RC D +EC + PC PG C + +F C+C PG
Sbjct: 497 RPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPGR-CENSPGSFRCVCGPGFRAG 554
Query: 508 ----QLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFS----GTRCEEDIDECRSSP 559
+ +V+ PC + C + F C+C G+ G C+ D+DEC SP
Sbjct: 555 PRAAECLDVDECHRVPPPC-DLGRCENTPGSFLCVCPAGYQAAPHGASCQ-DVDECTQSP 612
Query: 560 CANG-GQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVG-ASCLDLPGAFFCLCPS 617
G G C++ PG+F C C GF G C+ +VDEC +P P G C + G+F C CP+
Sbjct: 613 GLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPA 672
Query: 618 GFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRS-- 675
GF + P C+D + A +PP C +G C+ +
Sbjct: 673 GFRSR------------GPGAPCQDVDECAR----------SPP----PCTYGRCENTEG 706
Query: 676 --SCVCDVGW----TGPECEAELGGCISAPCAHGGTCYPQPSGYNC-TCPTGY--TGPTC 726
CVC +G+ G ECE ++ C + G C P + C TCP+G+ C
Sbjct: 707 SFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRC 765
Query: 727 SEEMTACHSG--PCLNGGSCNPSPGGYYCTCPPSHTGPQ-----CQTSTDYCVSAPCFNG 779
+ ++ C SG PC G C + G + C+C P + P C + CF
Sbjct: 766 T-DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPH 824
Query: 780 GTCVNRPGTFSCLCAMGFQ-GPRCEGKLR-PSCADSPCRNRATCQDSPQGPRCLCPTGYT 837
G C+N G+F+C CA G++ GPR L C++ C ++ C+CP G+
Sbjct: 825 GECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHR 884
Query: 838 GG----SCQTLMDLCAQKPCPRNSHCLQTGP-SFHCL--CLQGW-TGP--LCNLPLSSCQ 887
G SC + + + P S + P S+ C+ C G+ GP C+ + CQ
Sbjct: 885 AGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCD-DVDECQ 943
Query: 888 KAALSQGIDVSSLCHNGGLCVDSGPSYFC--HCPPGFQ---GSLCQDHVNPCESRP-CQN 941
+ +C C ++ SY C C PG+Q G CQD V+ C +R C
Sbjct: 944 EYG-------PEIC-GAQRCENTPGSYRCTPACDPGYQPTPGGGCQD-VDECRNRSFCGA 994
Query: 942 GATCMAQPSGYLCQCAPGY----DGQNCSKELDACQS-QPCHNHGTCTPKPGGFHCACP 995
A C P + C C GY DG++C +++ C++ Q C G F C CP
Sbjct: 995 HAVCQNLPGSFQCLCDQGYEGARDGRHC-VDVNECETLQGVCGAALCENVEGSFLCVCP 1052
Score = 234 bits (597), Expect = 6e-61
Identities = 301/1140 (26%), Positives = 408/1140 (35%), Gaps = 265/1140 (23%)
Query: 288 GGTCQD---GLDTYTCLCPETWTGWD------CSEDVDECETQGPPHCRNGGTCQNSAGS 338
GG C GL T C W CSE + E P G C
Sbjct: 228 GGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPD----GPCPTGFER 283
Query: 339 FHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLS 398
+ C E++D+C C + G ++C+CP G LL C+S
Sbjct: 284 VNGSC----------EDVDECATGGRCQHGECANTRGGYTCVCPDG--FLLDSSRSSCIS 331
Query: 399 Q--------PCH---GDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCE 447
Q PC D CS L T +C G +G C
Sbjct: 332 QHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAW----------GRGCQLCP 381
Query: 448 HGGSCLNTPGSFNCLCP--PGYTGSRCEADHNE----------CLSQPCHPGST---CLD 492
GS F +CP PGY S + +N LSQP +T
Sbjct: 382 PFGS-----EGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAG 436
Query: 493 LLATFHCLCP---------PGLE--------------------GQLCEVETNECASAPCL 523
L T H L P PG E +C+ C C+
Sbjct: 437 FLPT-HRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCI 495
Query: 524 NHADCHDLLNGFQCICLPGF----SGTRCEEDIDECR--SSPCANGGQCQDQPGAFHCKC 577
+ +G+ C C GF GTRC D+DECR PCA G+C++ PG+F C C
Sbjct: 496 SRP------SGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCA-PGRCENSPGSFRCVC 547
Query: 578 LPGFE-GPRCQ--TEVDEC--LSDPCPVGASCLDLPGAFFCLCPSGFT----GQLC-EVP 627
PGF GPR +VDEC + PC +G C + PG+F C+CP+G+ G C +V
Sbjct: 548 GPGFRAGPRAAECLDVDECHRVPPPCDLG-RCENTPGSFLCVCPAGYQAAPHGASCQDVD 606
Query: 628 LC--APNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTG 685
C +P LC + CK+ C+CP G+ G
Sbjct: 607 ECTQSPGLC-GRGACKNLPGSFRCVCP----------------------------AGFRG 637
Query: 686 PECEAELGGCISAPCAHG-GTCYPQPSGYNCTCPTGY----TGPTCSEEMTACHSGPCLN 740
CE ++ C P G G C ++C CP G+ G C + S P
Sbjct: 638 SACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCT 697
Query: 741 GGSCNPSPGGYYCTCP----PSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSC-LCAM 795
G C + G + C CP P+ G +C+ D C + G CVN PG+F C C
Sbjct: 698 YGRCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPS 756
Query: 796 G--FQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTG-----GSCQTLMDLC 848
G RC S PC C ++ RC C GY G C + +
Sbjct: 757 GHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECL 816
Query: 849 AQKPCPRNSHCLQTGPSFHCLCLQGW----TGPLCNLPLSSCQKAALSQGIDVSSLCHNG 904
C + CL T SF C C G+ G C L + C + L Q
Sbjct: 817 EGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQ----------S 865
Query: 905 GLCVDSGPSYFCHCPPGFQG----SLCQDHVNPCESR-PCQNGA-TCMAQPSGYLC--QC 956
G+C ++ S+ C CPPG + + C D V+ C R P G+ C P Y C C
Sbjct: 866 GICTNTDGSFECICPPGHRAGPDLASCLD-VDECRERGPALCGSQRCENSPGSYRCVRDC 924
Query: 957 APGYDG--QNCSKELDACQSQPCHNHGT--CTPKPGGFHC--ACPPGF---VGLRCEGDV 1007
PGY + ++D CQ G C PG + C AC PG+ G C+ DV
Sbjct: 925 DPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DV 983
Query: 1008 DECLDQPCHPTGTAACHSLANAFYCQCLPGH----TGQWCEVEIDPCHS-QPCFHGGTCE 1062
DEC ++ A C +L +F C C G+ G+ C V+++ C + Q CE
Sbjct: 984 DECRNR-SFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC-VDVNECETLQGVCGAALCE 1041
Query: 1063 ATAGSPLGFICHCPKG---FEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSG 1119
GS F+C CP F+ T G C+ PPR +
Sbjct: 1042 NVEGS---FLCVCPNSPEEFDPMT----------------GRCV-------PPRTSA-GT 1074
Query: 1120 YGGPDCLTPPAP-KGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGP-RCQKPGAKG 1177
+ G P +P PP P L + G G G R C + P C A+
Sbjct: 1075 FPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSG-RRECYFDTAAPDACDNILARN 1133
Query: 1178 CEGRSGDGACDAGCSGPGGNWDGG----DCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQC 1233
+ C C G W G C ++ H R +L G +
Sbjct: 1134 VTWQE----C---CCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLA-PSGDLSLRR 1185
Query: 1234 DSEEC-LFDGYDCETPPA--CTPAYDQYCHD--HFHNGHCE----KGCNTAECGWDGGDC 1284
D +EC LF C++ P Y YC + ++H E C E +GG C
Sbjct: 1186 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRC 1245
Score = 176 bits (446), Expect = 2e-43
Identities = 264/1028 (25%), Positives = 356/1028 (34%), Gaps = 197/1028 (19%)
Query: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAP 87
C P C G C +L G C C GF G C+ ++ C A P P
Sbjct: 608 CTQSPGLCGRGA-CKNLP-GSFRCVCPAGFRGSACE-----EDVDEC-------AQEPPP 653
Query: 88 LGLPSSPSPLTPSFLCTCLPGFT----GERCQAKLEDPCPPSFCSKRGRCHIQASGRPQC 143
G P SF C C GF G CQ E P C+ GRC G QC
Sbjct: 654 CG-PGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTY-GRCE-NTEGSFQC 710
Query: 144 SC----MPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCH-CPPGFEGHACE-RDVNE 197
C P G +C+ D C + G C+ + QC CP G H DV+E
Sbjct: 711 VCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDE 770
Query: 198 CFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPP-RGCSNGGTCQLMPE-- 254
C PC C NT GSF+C C G P R GPC C G C E
Sbjct: 771 CSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSG--RPGPCADVNECLEGDFCFPHGECL 828
Query: 255 -KDSTFHLCLCPPGFI----GPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETW-TG 308
D +F C C PG+ G C ++ D C G C + ++ C+CP G
Sbjct: 829 NTDGSF-ACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECICPPGHRAG 886
Query: 309 WDCSE--DVDECETQGPPHCRNGGTCQNSAGSFHCV--CVSGW--GGTSCEENLDDC--I 360
D + DVDEC +GP C C+NS GS+ CV C G+ G +++D+C
Sbjct: 887 PDLASCLDVDECRERGPALC-GSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEY 945
Query: 361 AATCAPGSTCIDRVGSFSCL--CPPG---RTGLLCHLEDMCLSQP-CHGDAQCSTNPLTG 414
C + GS+ C C PG G C D C ++ C A C P G
Sbjct: 946 GPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLP--G 1003
Query: 415 STLCLCQPGYSGPTCHQ---DLDEC--LMAQQGPSPCEHGGSCLNTPGSFNCLC------ 463
S CLC GY G + D++EC L G + CE N GSF C+C
Sbjct: 1004 SFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCE------NVEGSFLCVCPNSPEE 1057
Query: 464 ---------PPG-----YTGSRCEAD-----------------------------HNECL 480
PP + GS+ +A EC
Sbjct: 1058 FDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECY 1117
Query: 481 SQPCHPGSTCLDLLATF----HCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQ 536
P + C ++LA C C G EG +C + G+
Sbjct: 1118 FDTAAPDA-CDNILARNVTWQECCCTVG-EGWGSGCRIQQCPGTETAEYQSLCPHGRGY- 1174
Query: 537 CICLPGFSGTRCEEDIDEC---RSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEV--- 590
L D+DEC R C +G PG + C C G+ + E
Sbjct: 1175 ---LAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPG-YSCYCSNGYYYHTQRLECIDN 1230
Query: 591 DECLSD-PCPVGASCLDLPGAFFCLCPSGFTGQLCEVPL--------CAPNLCQPKQ--- 638
DEC + P G C++ G++ C C E PL C N Q
Sbjct: 1231 DECADEEPACEGGRCVNTVGSYHCTC---------EPPLVLDGSQRRCVSNESQSLDDNL 1281
Query: 639 -ICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCIS 697
+C Q+ A+ +C C C +G C + EA +
Sbjct: 1282 GVCW-QEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALCN--VL 1338
Query: 698 APCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPP 757
P A+ P+P G+ P Y GP GP L P P Y PP
Sbjct: 1339 RPPAYSP---PRPGGFGL--PYEY-GPDLGPPYQGLPYGPELY-----PPPALPYDPYPP 1387
Query: 758 SHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRN 817
GP + Y AP F+ + G + A GP P R+
Sbjct: 1388 P-PGPFARREAPY--GAPRFDMPDFEDDGGPYGESEAPAPPGPGTRW---------PYRS 1435
Query: 818 RATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCP-----RNSHCLQTGPSFHCLCLQ 872
R T + P+ Y G + +L A++ C N C++ F C C
Sbjct: 1436 RDTRRSFPEPEEPPEGGSYAGSLAEPYEELEAEE-CGILDGCTNGRCVRVPEGFTCRCFD 1494
Query: 873 GWTGPLCNLP---LSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQD 929
G+ + + ++ C +A + S LC N C+++ S+ C C PGF +
Sbjct: 1495 GYRLDMTRMACVDINECDEAEAA-----SPLCVNAR-CLNTDGSFRCICRPGFAPTHQPH 1548
Query: 930 HVNPCESR 937
H P R
Sbjct: 1549 HCAPARPR 1556
Score = 166 bits (420), Expect = 2e-40
Identities = 211/786 (26%), Positives = 281/786 (35%), Gaps = 178/786 (22%)
Query: 577 CLPGFEGPRCQTE-VDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQ 635
C GFE E VDEC + C + G + C+CP GF + + C
Sbjct: 277 CPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLD------SSRSSCI 330
Query: 636 PKQICKDQKDKANCLCPDGSPGCAPP------EDNCTCHH-GHCQRSSC-VCDVGWTGPE 687
+ + + K + DG GC+ P + C C G C +C G E
Sbjct: 331 SQHVISEAKGPCFRVLRDG--GCSLPILRNITKQICCCSRVGKAWGRGCQLCPP--FGSE 386
Query: 688 CEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEM------TACHSGPCLNG 741
E+ C + P H YN T P G P S T+ S L
Sbjct: 387 GFREI--CPAGPGYHYSA---SDLRYN-TRPLGQEPPRVSLSQPRTLPATSRPSAGFLPT 440
Query: 742 GSCNPSPG-------GYYCTCP--PSHTGPQCQTS---TDYCVSAPCFNG-GTCVNRPGT 788
P P G P P+ TGP+ S + C P G G C++RP
Sbjct: 441 HRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSG 500
Query: 789 FSCLCAMGF----QGPRCEG-----KLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGG 839
++C C GF QG RC ++ P CA C N SP RC+C G+ G
Sbjct: 501 YTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCEN------SPGSFRCVCGPGFRAG 554
Query: 840 SCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSS 899
PR + CL P C+L
Sbjct: 555 --------------PRAAECLDVDECHR-------VPPPCDL------------------ 575
Query: 900 LCHNGGLCVDSGPSYFCHCPPGFQ----GSLCQDHVNPCESRP--CQNGATCMAQPSGYL 953
G C ++ S+ C CP G+Q G+ CQD V+ C P C GA C P +
Sbjct: 576 -----GRCENTPGSFLCVCPAGYQAAPHGASCQD-VDECTQSPGLCGRGA-CKNLPGSFR 628
Query: 954 CQCAPGYDGQNCSKELDAC-QSQPCHNHGTCTPKPGGFHCACPPGF----VGLRCEGDVD 1008
C C G+ G C +++D C Q P G C G FHCACP GF G C+ DVD
Sbjct: 629 CVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQ-DVD 687
Query: 1009 ECLDQPCHPTGTAACHSLANAFYCQC----LPGHTGQWCEVEIDPCHSQPCFHGGTCEAT 1064
EC P P C + +F C C P G CE ++D C + G C +
Sbjct: 688 ECARSP-PPCTYGRCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNS 745
Query: 1065 AGS------PLGFICHCPKGFEGPTCSHRAPSCGFH-HCHHGGLCLPSPKPGFPPRCACL 1117
GS P G H + + CS AP CG H HC + + F RC+C
Sbjct: 746 PGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHC-------TNTEGSF--RCSCA 796
Query: 1118 SGYGGPDCLTPPAP--KGCGPPSPCLYNGSCSETTGLGGPGFRCSC-PHSSPGPRCQKPG 1174
GY P P C C +G C T G F C+C P PGPR G
Sbjct: 797 PGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDG----SFACTCAPGYRPGPR----G 848
Query: 1175 AK--GCEGRSGDGACDAG-CSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHP 1231
A + S + C +G C+ G+++ C P + P + C
Sbjct: 849 ASCLDVDECSEEDLCQSGICTNTDGSFE---CIC--PPGHRAGPDLASC----------- 892
Query: 1232 QCDSEECLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRPEDGDP 1291
D +EC G P C Q C + + C + C+ G C D
Sbjct: 893 -LDVDECRERG-----PALCG---SQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQ 943
Query: 1292 EWGPSL 1297
E+GP +
Sbjct: 944 EYGPEI 949
Score = 40.0 bits (92), Expect = 0.023
Identities = 76/305 (24%), Positives = 100/305 (32%), Gaps = 84/305 (27%)
Query: 24 RGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQAL 83
R LC P C NGG C+ C C P F G+ CQ G +++
Sbjct: 82 RAFLC---PLICHNGGVCVK----PDRCLCPPDFAGKFCQLHSSGARPPAPAVPGLTRSV 134
Query: 84 LPAPL--------GLPSSPS-----PLTPSFLCTCLPGFTGE------------RCQAKL 118
PL G+ S S P S + + +G A+
Sbjct: 135 YTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARA 194
Query: 119 EDPCPPSFCSKR-------------GRCHIQASGRPQCSCMPG--------------WTG 151
E P + ++ G C + G S +PG W
Sbjct: 195 EAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECASPLPGLRTQEVCCRGAGLAWGV 254
Query: 152 EQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFE--GHACERDVNECFQDPGPCPKGT 209
CQL CS + V P CP GFE +CE DV+EC G C G
Sbjct: 255 HDCQL---CSERLGNSERVSAPDGP-----CPTGFERVNGSCE-DVDECATG-GRCQHG- 303
Query: 210 SCHNTLGSFQCLCPVG----QEGPRC------ELRAGPCPPRGCSNGGTCQLMPEKDSTF 259
C NT G + C+CP G C GPC R +GG C L ++ T
Sbjct: 304 ECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPC-FRVLRDGG-CSLPILRNITK 361
Query: 260 HLCLC 264
+C C
Sbjct: 362 QICCC 366
Score = 38.9 bits (89), Expect = 0.051
Identities = 16/31 (51%), Positives = 18/31 (58%), Gaps = 3/31 (9%)
Query: 900 LCHNGGLCVDSGPSYFCHCPPGFQGSLCQDH 930
+CHNGG+CV C CPP F G CQ H
Sbjct: 89 ICHNGGVCVKPDR---CLCPPDFAGKFCQLH 116
Score = 38.1 bits (87), Expect = 0.087
Identities = 72/301 (23%), Positives = 90/301 (29%), Gaps = 73/301 (24%)
Query: 918 CPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPC 977
C G GS C P + +GA A P G PG+ C C
Sbjct: 45 CVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPGG------PGFRAFLCPLI--------C 90
Query: 978 HNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTG----TAACHSLANAFYCQ 1033
HN G C KP C CPP F G C+ H +G A L + Y
Sbjct: 91 HNGGVCV-KPD--RCLCPPDFAGKFCQ----------LHSSGARPPAPAVPGLTRSVYTM 137
Query: 1034 CLPGHT----GQWCEVEIDPCHSQPC-------------FHGGTCEATAGSPLGFICHCP 1076
L H G V + H Q + EA A +
Sbjct: 138 PLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEAA 197
Query: 1077 KGF-----EGPTCSHRAPSCGFHHCH---HGGLCLPSPKPGFPPRCACLSG----YGGPD 1124
+ P + + GF +C GG C SP PG + C G +G D
Sbjct: 198 APYTVLAQSAPREDGYSDASGFGYCFRELRGGEC-ASPLPGLRTQEVCCRGAGLAWGVHD 256
Query: 1125 CLTPPAPKG-----CGPPSPC-----LYNGSCSET--TGLGGPGFRCSCPHSSPGPRCQK 1172
C G P PC NGSC + GG C ++ G C
Sbjct: 257 CQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVC 316
Query: 1173 P 1173
P
Sbjct: 317 P 317
Score = 37.7 bits (86), Expect = 0.11
Identities = 22/70 (31%), Positives = 28/70 (40%), Gaps = 14/70 (20%)
Query: 939 CQNGATCMAQPSGYLCQCAPGY----------DGQNCSKELDACQSQPCHNHGTCTPKPG 988
C NG C+ P G+ C+C GY D C +A + P + C G
Sbjct: 1476 CTNGR-CVRVPEGFTCRCFDGYRLDMTRMACVDINECD---EAEAASPLCVNARCLNTDG 1531
Query: 989 GFHCACPPGF 998
F C C PGF
Sbjct: 1532 SFRCICRPGF 1541
Score = 36.6 bits (83), Expect = 0.25
Identities = 29/88 (32%), Positives = 35/88 (39%), Gaps = 18/88 (20%)
Query: 105 CLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSANP 164
C+ G TG RC C+ R + SG P PG G R F
Sbjct: 45 CVHGPTGSRCTPT---------CAPRNATSVD-SGAPG-GAAPGGPG----FRAFLCPLI 89
Query: 165 CVNGGVCLATYPQIQCHCPPGFEGHACE 192
C NGGVC+ +C CPP F G C+
Sbjct: 90 CHNGGVCVKPD---RCLCPPDFAGKFCQ 114
Score = 34.3 bits (77), Expect = 1.3
Identities = 28/109 (25%), Positives = 39/109 (35%), Gaps = 25/109 (22%)
Query: 1033 QCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCG 1092
+C+ G TG C P ++ G A G P GF C
Sbjct: 44 RCVHGPTGSRCTPTCAPRNATSVDSGAPGGAAPGGP---------GFRAFLCPLI----- 89
Query: 1093 FHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCL 1141
CH+GG+C+ P RC C + G C + G PP+P +
Sbjct: 90 ---CHNGGVCVK------PDRCLCPPDFAGKFCQLHSS--GARPPAPAV 127
Score = 32.7 bits (73), Expect = 3.7
Identities = 15/37 (40%), Positives = 21/37 (56%), Gaps = 7/37 (18%)
Query: 240 PRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVN 276
P C NGG C + P++ CLCPP F G C+++
Sbjct: 87 PLICHNGGVC-VKPDR------CLCPPDFAGKFCQLH 116
>gi|110347412 latent transforming growth factor beta binding protein 4
isoform b [Homo sapiens]
Length = 1587
Score = 268 bits (685), Expect = 4e-71
Identities = 312/1108 (28%), Positives = 410/1108 (37%), Gaps = 270/1108 (24%)
Query: 306 WTGWDCSEDVDECET-QGPPHCRNGGTCQNSAGSFHCVCVSGWG----GTSCEENLDDC- 359
WTG + E Q P G C + + C C SG+ GT C + +D+C
Sbjct: 497 WTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCID-VDECR 555
Query: 360 -IAATCAPGSTCIDRVGSFSCLCPPG-RTG---LLCHLEDMCLSQPCHGD-AQCSTNPLT 413
+ CAPG C + GSF C+C PG R G C D C P D +C P
Sbjct: 556 RVPPPCAPGR-CENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTP-- 612
Query: 414 GSTLCLCQPGYS----GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTG 469
GS LC+C GY G +C QD+DEC Q P C G +C N PGSF C+CP G+ G
Sbjct: 613 GSFLCVCPAGYQAAPHGASC-QDVDECT---QSPGLCGRG-ACKNLPGSFRCVCPAGFRG 667
Query: 470 SRCEADHNECLSQP--CHPGSTCLDLLATFHCLCPPGLE----GQLCEVETNECA-SAPC 522
S CE D +EC +P C PG C + +FHC CP G G C+ + +ECA S P
Sbjct: 668 SACEEDVDECAQEPPPCGPGR-CDNTAGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPP 725
Query: 523 LNHADCHDLLNGFQCICLPGF----SGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCL 578
+ C + FQC+C GF +G+ CE D+DEC + G +C + PG+F C+
Sbjct: 726 CTYGRCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTC 784
Query: 579 PG---FEGPRCQTEVDECLSD--PCPVGASCLDLPGAFFCLC------PSGFTGQLCEVP 627
P RC T+VDEC S PC C + G+F C C PSG G +V
Sbjct: 785 PSGHHLHRGRC-TDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVN 843
Query: 628 LCAP-NLCQPKQICKDQKDKANCLCPDG-SPGCAPPE----DNCT----CHHGHCQRSS- 676
C + C P C + C C G PG D C+ C G C +
Sbjct: 844 ECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDG 903
Query: 677 ---CVCDVGW-TGPECEAELGGCISAP-CAHGGT-------CYPQPSGYNCT--CPTGY- 721
C+C G GP+ L C+ C G C P Y C C GY
Sbjct: 904 SFECICPPGHRAGPD----LASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYH 959
Query: 722 TGP--TCSEEMTACHSGPCLNGGS-CNPSPGGYYCT--CPPSHT---GPQCQTSTDYCVS 773
GP TC + GP + G C +PG Y CT C P + G CQ +
Sbjct: 960 AGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNR 1019
Query: 774 APCFNGGTCVNRPGTFSCLCAMGFQGPR----------CEGKLRPSCADSPCRN-----R 818
+ C C N PG+F CLC G++G R CE L+ C + C N
Sbjct: 1020 SFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECE-TLQGVCGAALCENVEGSFL 1078
Query: 819 ATCQDSPQG-----PRCLCPTGYTGG---------SCQTLMDLCAQKPCPRNSHCLQTGP 864
C +SP+ RC+ P G + L P PR + GP
Sbjct: 1079 CVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGP 1138
Query: 865 SF---------------------------HCLCL--QGWTGPLCNLPLSSCQKAALSQGI 895
C C +GW G C + Q+ ++
Sbjct: 1139 VGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGW-GSGCRI-----QQCPGTETA 1192
Query: 896 DVSSLC-HNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCE---SRPCQNGATCMAQPSG 951
+ SLC H G SG SL +D V+ C+ + C++G C+ G
Sbjct: 1193 EYQSLCPHGRGYLAPSGDL-----------SLRRD-VDECQLFRDQVCKSGV-CVNTAPG 1239
Query: 952 YLCQCAPGY----------DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFV-- 999
Y C C+ GY D C+ E AC+ G C G +HC C P V
Sbjct: 1240 YSCYCSNGYYYHTQRLECIDNDECADEEPACEG------GRCVNTVGSYHCTCEPPLVLD 1293
Query: 1000 --GLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQP--- 1054
RC + + LD N C W EV D S P
Sbjct: 1294 GSQRRCVSNESQSLDD--------------NLGVC---------WQEVGADLVCSHPRLD 1330
Query: 1055 ---------CFHG-------GTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHH 1098
C +G C A +C+ P S P GF +
Sbjct: 1331 RQATYTECCCLYGEAWGMDCALCPAQDSDDFEALCNV---LRPPAYSPPRPG-GFGLPYE 1386
Query: 1099 GGLCLPSPKPGFPPRCACLSGYGGPDCLTPPA-PKGCGPPSPCLYNGSCSETTGLGGPGF 1157
G L P G P GP+ PPA P PP P GP
Sbjct: 1387 YGPDLGPPYQGLP---------YGPELYPPPALPYDPYPPPP--------------GPFA 1423
Query: 1158 RCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWD--GGDCSLGVPDPWKGCP 1215
R P+ + PR P + G G+ A GPG W D P+P +
Sbjct: 1424 RREAPYGA--PRFDMPDFEDDGGPYGESEAPAP-PGPGTRWPYRSRDTRRSFPEPEEPPE 1480
Query: 1216 SHSRCWLLFRDGQCHPQCDSEEC-LFDG 1242
S L + + + ++EEC + DG
Sbjct: 1481 GGSYAGSL---AEPYEELEAEECGILDG 1505
Score = 263 bits (672), Expect = 1e-69
Identities = 251/840 (29%), Positives = 337/840 (40%), Gaps = 165/840 (19%)
Query: 85 PAPLGLPSSPSPLTPSFLCTCLP--GFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQ 142
P P P P P P++ +P G + CQ P C GRC + SG
Sbjct: 481 PDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRN------PQVCGP-GRCISRPSGYT- 532
Query: 143 CSCMPGWT----GEQCQLRDFCSA--NPCVNGGVCLATYPQIQCHCPPGFEG--HACE-R 193
C+C G+ G +C D C PC G C + +C C PGF A E
Sbjct: 533 CACDSGFRLSPQGTRCIDVDECRRVPPPCAPGR-CENSPGSFRCVCGPGFRAGPRAAECL 591
Query: 194 DVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQE----GPRCELRAGPCPPRGCSNGGTC 249
DV+EC + P PC G C NT GSF C+CP G + G C+ G G C
Sbjct: 592 DVDECHRVPPPCDLGR-CENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGAC 650
Query: 250 QLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNG-GTCQDGLDTYTCLCPETWT- 307
+ +P +F C+CP GF G CE + D C G G C + ++ C CP +
Sbjct: 651 KNLP---GSFR-CVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRS 706
Query: 308 ---GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDCI 360
G C +DVDEC + PP C G C+N+ GSF CVC G+ G+ CE+ +D+C
Sbjct: 707 RGPGAPC-QDVDEC-ARSPPPCTYG-RCENTEGSFQCVCPMGFQPNTAGSECED-VDECE 762
Query: 361 AATCAPGSTCIDRVGSFSC-LCPPGRT--GLLCHLEDMCLS--QPCHGDAQCSTNPLTGS 415
PG C++ GSF C CP G C D C S PC C+ GS
Sbjct: 763 NHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTE--GS 820
Query: 416 TLCLCQPGYSGPTCHQ----DLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT--- 468
C C PGY P+ D++ECL C G CLNT GSF C C PGY
Sbjct: 821 FRCSCAPGYRAPSGRPGPCADVNECLEGDF----CFPHGECLNTDGSFACTCAPGYRPGP 876
Query: 469 -GSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPG------LEGQLCEVETNECASAP 521
G+ C D +EC + C + +F C+CPPG L L E E A
Sbjct: 877 RGASC-LDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPAL 935
Query: 522 CLNHADCHDLLNGFQCI--CLPGF----SGTRCEEDIDECRS-SPCANGGQ-CQDQPGAF 573
C + C + ++C+ C PG+ GT C+ D+DEC+ P G Q C++ PG++
Sbjct: 936 CGSQR-CENSPGSYRCVRDCDPGYHAGPEGT-CD-DVDECQEYGPEICGAQRCENTPGSY 992
Query: 574 HCK--CLPGFE---GPRCQTEVDECLSDP-CPVGASCLDLPGAFFCLCPSGFTGQLCEVP 627
C C PG++ G CQ +VDEC + C A C +LPG+F CLC G+ G
Sbjct: 993 RCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRH 1051
Query: 628 LCAPNLCQPKQ------ICKDQKDKANCLCPDG-------SPGCAPPEDNCTCHHGH--- 671
N C+ Q +C++ + C+CP+ + C PP + G
Sbjct: 1052 CVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQ 1111
Query: 672 -----------------------------CQRSSCVCDVGW------------TGPECEA 690
R C D T EC
Sbjct: 1112 APASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCC 1171
Query: 691 ELGGCISAPCAHGGTCYPQPSGYNCTCP--TGYTGPTCSEEMT------------ACHSG 736
+G + C + + Y CP GY P+ + C SG
Sbjct: 1172 TVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSG 1231
Query: 737 PCLN---GGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLC 793
C+N G SC S G YY T +C + + P GG CVN G++ C C
Sbjct: 1232 VCVNTAPGYSCYCSNGYYYHT-----QRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 1286
Score = 237 bits (604), Expect = 1e-61
Identities = 229/839 (27%), Positives = 333/839 (39%), Gaps = 193/839 (23%)
Query: 289 GTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGW- 347
G C G + C EDVDEC T G C++G C N+ G + CVC G+
Sbjct: 305 GPCPTGFERVNGSC----------EDVDECATGG--RCQHG-ECANTRGGYTCVCPDGFL 351
Query: 348 ---GGTSC------EENLDDCIAATCAPGST------------CIDRVGSF---SC-LCP 382
+SC E C G + C RVG C LCP
Sbjct: 352 LDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCP 411
Query: 383 P-GRTGLLCHLEDMCLSQPCH----GDAQCSTNPL------------------------- 412
P G G ++C + P + D + +T PL
Sbjct: 412 PFGSEGF----REICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGF 467
Query: 413 -----------------TGSTLCLCQ-PGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLN 454
G L L P ++GP + M Q+ P C G C++
Sbjct: 468 LPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPG-RCIS 526
Query: 455 TPGSFNCLCPPGYT----GSRCEADHNEC--LSQPCHPGSTCLDLLATFHCLCPPGLEG- 507
P + C C G+ G+RC D +EC + PC PG C + +F C+C PG
Sbjct: 527 RPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPGR-CENSPGSFRCVCGPGFRAG 584
Query: 508 ----QLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFS----GTRCEEDIDECRSSP 559
+ +V+ PC + C + F C+C G+ G C+ D+DEC SP
Sbjct: 585 PRAAECLDVDECHRVPPPC-DLGRCENTPGSFLCVCPAGYQAAPHGASCQ-DVDECTQSP 642
Query: 560 CANG-GQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVG-ASCLDLPGAFFCLCPS 617
G G C++ PG+F C C GF G C+ +VDEC +P P G C + G+F C CP+
Sbjct: 643 GLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPA 702
Query: 618 GFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRS-- 675
GF + P C+D + A +PP C +G C+ +
Sbjct: 703 GFRSR------------GPGAPCQDVDECAR----------SPP----PCTYGRCENTEG 736
Query: 676 --SCVCDVGW----TGPECEAELGGCISAPCAHGGTCYPQPSGYNC-TCPTGY--TGPTC 726
CVC +G+ G ECE ++ C + G C P + C TCP+G+ C
Sbjct: 737 SFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRC 795
Query: 727 SEEMTACHSG--PCLNGGSCNPSPGGYYCTCPPSHTGPQ-----CQTSTDYCVSAPCFNG 779
+ ++ C SG PC G C + G + C+C P + P C + CF
Sbjct: 796 T-DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPH 854
Query: 780 GTCVNRPGTFSCLCAMGFQ-GPRCEGKLR-PSCADSPCRNRATCQDSPQGPRCLCPTGYT 837
G C+N G+F+C CA G++ GPR L C++ C ++ C+CP G+
Sbjct: 855 GECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHR 914
Query: 838 GG----SCQTLMDLCAQKPCPRNSHCLQTGP-SFHCL--CLQGW-TGP--LCNLPLSSCQ 887
G SC + + + P S + P S+ C+ C G+ GP C+ + CQ
Sbjct: 915 AGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCD-DVDECQ 973
Query: 888 KAALSQGIDVSSLCHNGGLCVDSGPSYFC--HCPPGFQ---GSLCQDHVNPCESRP-CQN 941
+ +C C ++ SY C C PG+Q G CQD V+ C +R C
Sbjct: 974 EYG-------PEIC-GAQRCENTPGSYRCTPACDPGYQPTPGGGCQD-VDECRNRSFCGA 1024
Query: 942 GATCMAQPSGYLCQCAPGY----DGQNCSKELDACQS-QPCHNHGTCTPKPGGFHCACP 995
A C P + C C GY DG++C +++ C++ Q C G F C CP
Sbjct: 1025 HAVCQNLPGSFQCLCDQGYEGARDGRHC-VDVNECETLQGVCGAALCENVEGSFLCVCP 1082
Score = 234 bits (597), Expect = 6e-61
Identities = 301/1140 (26%), Positives = 408/1140 (35%), Gaps = 265/1140 (23%)
Query: 288 GGTCQD---GLDTYTCLCPETWTGWD------CSEDVDECETQGPPHCRNGGTCQNSAGS 338
GG C GL T C W CSE + E P G C
Sbjct: 258 GGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPD----GPCPTGFER 313
Query: 339 FHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLS 398
+ C E++D+C C + G ++C+CP G LL C+S
Sbjct: 314 VNGSC----------EDVDECATGGRCQHGECANTRGGYTCVCPDG--FLLDSSRSSCIS 361
Query: 399 Q--------PCH---GDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCE 447
Q PC D CS L T +C G +G C
Sbjct: 362 QHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAW----------GRGCQLCP 411
Query: 448 HGGSCLNTPGSFNCLCP--PGYTGSRCEADHNE----------CLSQPCHPGST---CLD 492
GS F +CP PGY S + +N LSQP +T
Sbjct: 412 PFGS-----EGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAG 466
Query: 493 LLATFHCLCP---------PGLE--------------------GQLCEVETNECASAPCL 523
L T H L P PG E +C+ C C+
Sbjct: 467 FLPT-HRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCI 525
Query: 524 NHADCHDLLNGFQCICLPGF----SGTRCEEDIDECR--SSPCANGGQCQDQPGAFHCKC 577
+ +G+ C C GF GTRC D+DECR PCA G+C++ PG+F C C
Sbjct: 526 SRP------SGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCA-PGRCENSPGSFRCVC 577
Query: 578 LPGFE-GPRCQ--TEVDEC--LSDPCPVGASCLDLPGAFFCLCPSGFT----GQLC-EVP 627
PGF GPR +VDEC + PC +G C + PG+F C+CP+G+ G C +V
Sbjct: 578 GPGFRAGPRAAECLDVDECHRVPPPCDLG-RCENTPGSFLCVCPAGYQAAPHGASCQDVD 636
Query: 628 LC--APNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTG 685
C +P LC + CK+ C+CP G+ G
Sbjct: 637 ECTQSPGLC-GRGACKNLPGSFRCVCP----------------------------AGFRG 667
Query: 686 PECEAELGGCISAPCAHG-GTCYPQPSGYNCTCPTGY----TGPTCSEEMTACHSGPCLN 740
CE ++ C P G G C ++C CP G+ G C + S P
Sbjct: 668 SACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCT 727
Query: 741 GGSCNPSPGGYYCTCP----PSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSC-LCAM 795
G C + G + C CP P+ G +C+ D C + G CVN PG+F C C
Sbjct: 728 YGRCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPS 786
Query: 796 G--FQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTG-----GSCQTLMDLC 848
G RC S PC C ++ RC C GY G C + +
Sbjct: 787 GHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECL 846
Query: 849 AQKPCPRNSHCLQTGPSFHCLCLQGW----TGPLCNLPLSSCQKAALSQGIDVSSLCHNG 904
C + CL T SF C C G+ G C L + C + L Q
Sbjct: 847 EGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQ----------S 895
Query: 905 GLCVDSGPSYFCHCPPGFQG----SLCQDHVNPCESR-PCQNGA-TCMAQPSGYLC--QC 956
G+C ++ S+ C CPPG + + C D V+ C R P G+ C P Y C C
Sbjct: 896 GICTNTDGSFECICPPGHRAGPDLASCLD-VDECRERGPALCGSQRCENSPGSYRCVRDC 954
Query: 957 APGYDG--QNCSKELDACQSQPCHNHGT--CTPKPGGFHC--ACPPGF---VGLRCEGDV 1007
PGY + ++D CQ G C PG + C AC PG+ G C+ DV
Sbjct: 955 DPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DV 1013
Query: 1008 DECLDQPCHPTGTAACHSLANAFYCQCLPGH----TGQWCEVEIDPCHS-QPCFHGGTCE 1062
DEC ++ A C +L +F C C G+ G+ C V+++ C + Q CE
Sbjct: 1014 DECRNR-SFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC-VDVNECETLQGVCGAALCE 1071
Query: 1063 ATAGSPLGFICHCPKG---FEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSG 1119
GS F+C CP F+ T G C+ PPR +
Sbjct: 1072 NVEGS---FLCVCPNSPEEFDPMT----------------GRCV-------PPRTSA-GT 1104
Query: 1120 YGGPDCLTPPAP-KGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGP-RCQKPGAKG 1177
+ G P +P PP P L + G G G R C + P C A+
Sbjct: 1105 FPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSG-RRECYFDTAAPDACDNILARN 1163
Query: 1178 CEGRSGDGACDAGCSGPGGNWDGG----DCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQC 1233
+ C C G W G C ++ H R +L G +
Sbjct: 1164 VTWQE----C---CCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLA-PSGDLSLRR 1215
Query: 1234 DSEEC-LFDGYDCETPPA--CTPAYDQYCHD--HFHNGHCE----KGCNTAECGWDGGDC 1284
D +EC LF C++ P Y YC + ++H E C E +GG C
Sbjct: 1216 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRC 1275
Score = 176 bits (446), Expect = 2e-43
Identities = 264/1028 (25%), Positives = 356/1028 (34%), Gaps = 197/1028 (19%)
Query: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAP 87
C P C G C +L G C C GF G C+ ++ C A P P
Sbjct: 638 CTQSPGLCGRGA-CKNLP-GSFRCVCPAGFRGSACE-----EDVDEC-------AQEPPP 683
Query: 88 LGLPSSPSPLTPSFLCTCLPGFT----GERCQAKLEDPCPPSFCSKRGRCHIQASGRPQC 143
G P SF C C GF G CQ E P C+ GRC G QC
Sbjct: 684 CG-PGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTY-GRCE-NTEGSFQC 740
Query: 144 SC----MPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCH-CPPGFEGHACE-RDVNE 197
C P G +C+ D C + G C+ + QC CP G H DV+E
Sbjct: 741 VCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDE 800
Query: 198 CFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPP-RGCSNGGTCQLMPE-- 254
C PC C NT GSF+C C G P R GPC C G C E
Sbjct: 801 CSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSG--RPGPCADVNECLEGDFCFPHGECL 858
Query: 255 -KDSTFHLCLCPPGFI----GPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETW-TG 308
D +F C C PG+ G C ++ D C G C + ++ C+CP G
Sbjct: 859 NTDGSF-ACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECICPPGHRAG 916
Query: 309 WDCSE--DVDECETQGPPHCRNGGTCQNSAGSFHCV--CVSGW--GGTSCEENLDDC--I 360
D + DVDEC +GP C C+NS GS+ CV C G+ G +++D+C
Sbjct: 917 PDLASCLDVDECRERGPALC-GSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEY 975
Query: 361 AATCAPGSTCIDRVGSFSCL--CPPG---RTGLLCHLEDMCLSQP-CHGDAQCSTNPLTG 414
C + GS+ C C PG G C D C ++ C A C P G
Sbjct: 976 GPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLP--G 1033
Query: 415 STLCLCQPGYSGPTCHQ---DLDEC--LMAQQGPSPCEHGGSCLNTPGSFNCLC------ 463
S CLC GY G + D++EC L G + CE N GSF C+C
Sbjct: 1034 SFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCE------NVEGSFLCVCPNSPEE 1087
Query: 464 ---------PPG-----YTGSRCEAD-----------------------------HNECL 480
PP + GS+ +A EC
Sbjct: 1088 FDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECY 1147
Query: 481 SQPCHPGSTCLDLLATF----HCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQ 536
P + C ++LA C C G EG +C + G+
Sbjct: 1148 FDTAAPDA-CDNILARNVTWQECCCTVG-EGWGSGCRIQQCPGTETAEYQSLCPHGRGY- 1204
Query: 537 CICLPGFSGTRCEEDIDEC---RSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEV--- 590
L D+DEC R C +G PG + C C G+ + E
Sbjct: 1205 ---LAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPG-YSCYCSNGYYYHTQRLECIDN 1260
Query: 591 DECLSD-PCPVGASCLDLPGAFFCLCPSGFTGQLCEVPL--------CAPNLCQPKQ--- 638
DEC + P G C++ G++ C C E PL C N Q
Sbjct: 1261 DECADEEPACEGGRCVNTVGSYHCTC---------EPPLVLDGSQRRCVSNESQSLDDNL 1311
Query: 639 -ICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCIS 697
+C Q+ A+ +C C C +G C + EA +
Sbjct: 1312 GVCW-QEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALCN--VL 1368
Query: 698 APCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPP 757
P A+ P+P G+ P Y GP GP L P P Y PP
Sbjct: 1369 RPPAYSP---PRPGGFGL--PYEY-GPDLGPPYQGLPYGPELY-----PPPALPYDPYPP 1417
Query: 758 SHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRN 817
GP + Y AP F+ + G + A GP P R+
Sbjct: 1418 P-PGPFARREAPY--GAPRFDMPDFEDDGGPYGESEAPAPPGPGTRW---------PYRS 1465
Query: 818 RATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCP-----RNSHCLQTGPSFHCLCLQ 872
R T + P+ Y G + +L A++ C N C++ F C C
Sbjct: 1466 RDTRRSFPEPEEPPEGGSYAGSLAEPYEELEAEE-CGILDGCTNGRCVRVPEGFTCRCFD 1524
Query: 873 GWTGPLCNLP---LSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQD 929
G+ + + ++ C +A + S LC N C+++ S+ C C PGF +
Sbjct: 1525 GYRLDMTRMACVDINECDEAEAA-----SPLCVNAR-CLNTDGSFRCICRPGFAPTHQPH 1578
Query: 930 HVNPCESR 937
H P R
Sbjct: 1579 HCAPARPR 1586
Score = 166 bits (420), Expect = 2e-40
Identities = 211/786 (26%), Positives = 281/786 (35%), Gaps = 178/786 (22%)
Query: 577 CLPGFEGPRCQTE-VDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQ 635
C GFE E VDEC + C + G + C+CP GF + + C
Sbjct: 307 CPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLD------SSRSSCI 360
Query: 636 PKQICKDQKDKANCLCPDGSPGCAPP------EDNCTCHH-GHCQRSSC-VCDVGWTGPE 687
+ + + K + DG GC+ P + C C G C +C G E
Sbjct: 361 SQHVISEAKGPCFRVLRDG--GCSLPILRNITKQICCCSRVGKAWGRGCQLCPP--FGSE 416
Query: 688 CEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEM------TACHSGPCLNG 741
E+ C + P H YN T P G P S T+ S L
Sbjct: 417 GFREI--CPAGPGYHYSA---SDLRYN-TRPLGQEPPRVSLSQPRTLPATSRPSAGFLPT 470
Query: 742 GSCNPSPG-------GYYCTCP--PSHTGPQCQTS---TDYCVSAPCFNG-GTCVNRPGT 788
P P G P P+ TGP+ S + C P G G C++RP
Sbjct: 471 HRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSG 530
Query: 789 FSCLCAMGF----QGPRCEG-----KLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGG 839
++C C GF QG RC ++ P CA C N SP RC+C G+ G
Sbjct: 531 YTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCEN------SPGSFRCVCGPGFRAG 584
Query: 840 SCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSS 899
PR + CL P C+L
Sbjct: 585 --------------PRAAECLDVDECHR-------VPPPCDL------------------ 605
Query: 900 LCHNGGLCVDSGPSYFCHCPPGFQ----GSLCQDHVNPCESRP--CQNGATCMAQPSGYL 953
G C ++ S+ C CP G+Q G+ CQD V+ C P C GA C P +
Sbjct: 606 -----GRCENTPGSFLCVCPAGYQAAPHGASCQD-VDECTQSPGLCGRGA-CKNLPGSFR 658
Query: 954 CQCAPGYDGQNCSKELDAC-QSQPCHNHGTCTPKPGGFHCACPPGF----VGLRCEGDVD 1008
C C G+ G C +++D C Q P G C G FHCACP GF G C+ DVD
Sbjct: 659 CVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQ-DVD 717
Query: 1009 ECLDQPCHPTGTAACHSLANAFYCQC----LPGHTGQWCEVEIDPCHSQPCFHGGTCEAT 1064
EC P P C + +F C C P G CE ++D C + G C +
Sbjct: 718 ECARSP-PPCTYGRCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNS 775
Query: 1065 AGS------PLGFICHCPKGFEGPTCSHRAPSCGFH-HCHHGGLCLPSPKPGFPPRCACL 1117
GS P G H + + CS AP CG H HC + + F RC+C
Sbjct: 776 PGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHC-------TNTEGSF--RCSCA 826
Query: 1118 SGYGGPDCLTPPAP--KGCGPPSPCLYNGSCSETTGLGGPGFRCSC-PHSSPGPRCQKPG 1174
GY P P C C +G C T G F C+C P PGPR G
Sbjct: 827 PGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDG----SFACTCAPGYRPGPR----G 878
Query: 1175 AK--GCEGRSGDGACDAG-CSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHP 1231
A + S + C +G C+ G+++ C P + P + C
Sbjct: 879 ASCLDVDECSEEDLCQSGICTNTDGSFE---CIC--PPGHRAGPDLASC----------- 922
Query: 1232 QCDSEECLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRPEDGDP 1291
D +EC G P C Q C + + C + C+ G C D
Sbjct: 923 -LDVDECRERG-----PALCG---SQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQ 973
Query: 1292 EWGPSL 1297
E+GP +
Sbjct: 974 EYGPEI 979
Score = 38.9 bits (89), Expect = 0.051
Identities = 16/31 (51%), Positives = 18/31 (58%), Gaps = 3/31 (9%)
Query: 900 LCHNGGLCVDSGPSYFCHCPPGFQGSLCQDH 930
+CHNGG+CV C CPP F G CQ H
Sbjct: 119 ICHNGGVCVKPDR---CLCPPDFAGKFCQLH 146
Score = 38.9 bits (89), Expect = 0.051
Identities = 34/95 (35%), Positives = 42/95 (44%), Gaps = 17/95 (17%)
Query: 182 CPPGFE--GHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG----QEGPRC---- 231
CP GFE +CE DV+EC G C G C NT G + C+CP G C
Sbjct: 307 CPTGFERVNGSCE-DVDECATG-GRCQHG-ECANTRGGYTCVCPDGFLLDSSRSSCISQH 363
Query: 232 --ELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLC 264
GPC R +GG C L ++ T +C C
Sbjct: 364 VISEAKGPC-FRVLRDGG-CSLPILRNITKQICCC 396
Score = 37.7 bits (86), Expect = 0.11
Identities = 22/70 (31%), Positives = 28/70 (40%), Gaps = 14/70 (20%)
Query: 939 CQNGATCMAQPSGYLCQCAPGY----------DGQNCSKELDACQSQPCHNHGTCTPKPG 988
C NG C+ P G+ C+C GY D C +A + P + C G
Sbjct: 1506 CTNGR-CVRVPEGFTCRCFDGYRLDMTRMACVDINECD---EAEAASPLCVNARCLNTDG 1561
Query: 989 GFHCACPPGF 998
F C C PGF
Sbjct: 1562 SFRCICRPGF 1571
Score = 33.5 bits (75), Expect = 2.1
Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 10/45 (22%)
Query: 235 AGPCP---PRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVN 276
AG P P C NGG C + P++ CLCPP F G C+++
Sbjct: 109 AGKAPVLCPLICHNGGVC-VKPDR------CLCPPDFAGKFCQLH 146
Score = 33.1 bits (74), Expect = 2.8
Identities = 58/242 (23%), Positives = 73/242 (30%), Gaps = 59/242 (24%)
Query: 977 CHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTG----TAACHSLANAFYC 1032
CHN G C KP C CPP F G C+ H +G A L + Y
Sbjct: 120 CHNGGVCV-KPD--RCLCPPDFAGKFCQ----------LHSSGARPPAPAVPGLTRSVYT 166
Query: 1033 QCLPGHT----GQWCEVEIDPCHSQPC-------------FHGGTCEATAGSPLGFICHC 1075
L H G V + H Q + EA A +
Sbjct: 167 MPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEA 226
Query: 1076 PKGF-----EGPTCSHRAPSCGFHHCH---HGGLCLPSPKPGFPPRCACLSG----YGGP 1123
+ P + + GF +C GG C SP PG + C G +G
Sbjct: 227 AAPYTVLAQSAPREDGYSDASGFGYCFRELRGGEC-ASPLPGLRTQEVCCRGAGLAWGVH 285
Query: 1124 DCLTPPAPKG-----CGPPSPC-----LYNGSCSET--TGLGGPGFRCSCPHSSPGPRCQ 1171
DC G P PC NGSC + GG C ++ G C
Sbjct: 286 DCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCV 345
Query: 1172 KP 1173
P
Sbjct: 346 CP 347
>gi|110347431 latent transforming growth factor beta binding protein 4
isoform a [Homo sapiens]
Length = 1624
Score = 268 bits (685), Expect = 4e-71
Identities = 312/1108 (28%), Positives = 410/1108 (37%), Gaps = 270/1108 (24%)
Query: 306 WTGWDCSEDVDECET-QGPPHCRNGGTCQNSAGSFHCVCVSGWG----GTSCEENLDDC- 359
WTG + E Q P G C + + C C SG+ GT C + +D+C
Sbjct: 534 WTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCID-VDECR 592
Query: 360 -IAATCAPGSTCIDRVGSFSCLCPPG-RTG---LLCHLEDMCLSQPCHGD-AQCSTNPLT 413
+ CAPG C + GSF C+C PG R G C D C P D +C P
Sbjct: 593 RVPPPCAPGR-CENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTP-- 649
Query: 414 GSTLCLCQPGYS----GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTG 469
GS LC+C GY G +C QD+DEC Q P C G +C N PGSF C+CP G+ G
Sbjct: 650 GSFLCVCPAGYQAAPHGASC-QDVDECT---QSPGLCGRG-ACKNLPGSFRCVCPAGFRG 704
Query: 470 SRCEADHNECLSQP--CHPGSTCLDLLATFHCLCPPGLE----GQLCEVETNECA-SAPC 522
S CE D +EC +P C PG C + +FHC CP G G C+ + +ECA S P
Sbjct: 705 SACEEDVDECAQEPPPCGPGR-CDNTAGSFHCACPAGFRSRGPGAPCQ-DVDECARSPPP 762
Query: 523 LNHADCHDLLNGFQCICLPGF----SGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCL 578
+ C + FQC+C GF +G+ CE D+DEC + G +C + PG+F C+
Sbjct: 763 CTYGRCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTC 821
Query: 579 PG---FEGPRCQTEVDECLSD--PCPVGASCLDLPGAFFCLC------PSGFTGQLCEVP 627
P RC T+VDEC S PC C + G+F C C PSG G +V
Sbjct: 822 PSGHHLHRGRC-TDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVN 880
Query: 628 LCAP-NLCQPKQICKDQKDKANCLCPDG-SPGCAPPE----DNCT----CHHGHCQRSS- 676
C + C P C + C C G PG D C+ C G C +
Sbjct: 881 ECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDG 940
Query: 677 ---CVCDVGW-TGPECEAELGGCISAP-CAHGGT-------CYPQPSGYNCT--CPTGY- 721
C+C G GP+ L C+ C G C P Y C C GY
Sbjct: 941 SFECICPPGHRAGPD----LASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYH 996
Query: 722 TGP--TCSEEMTACHSGPCLNGGS-CNPSPGGYYCT--CPPSHT---GPQCQTSTDYCVS 773
GP TC + GP + G C +PG Y CT C P + G CQ +
Sbjct: 997 AGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNR 1056
Query: 774 APCFNGGTCVNRPGTFSCLCAMGFQGPR----------CEGKLRPSCADSPCRN-----R 818
+ C C N PG+F CLC G++G R CE L+ C + C N
Sbjct: 1057 SFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHCVDVNECE-TLQGVCGAALCENVEGSFL 1115
Query: 819 ATCQDSPQG-----PRCLCPTGYTGG---------SCQTLMDLCAQKPCPRNSHCLQTGP 864
C +SP+ RC+ P G + L P PR + GP
Sbjct: 1116 CVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGP 1175
Query: 865 SF---------------------------HCLCL--QGWTGPLCNLPLSSCQKAALSQGI 895
C C +GW G C + Q+ ++
Sbjct: 1176 VGSGRRECYFDTAAPDACDNILARNVTWQECCCTVGEGW-GSGCRI-----QQCPGTETA 1229
Query: 896 DVSSLC-HNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCE---SRPCQNGATCMAQPSG 951
+ SLC H G SG SL +D V+ C+ + C++G C+ G
Sbjct: 1230 EYQSLCPHGRGYLAPSGDL-----------SLRRD-VDECQLFRDQVCKSGV-CVNTAPG 1276
Query: 952 YLCQCAPGY----------DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFV-- 999
Y C C+ GY D C+ E AC+ G C G +HC C P V
Sbjct: 1277 YSCYCSNGYYYHTQRLECIDNDECADEEPACEG------GRCVNTVGSYHCTCEPPLVLD 1330
Query: 1000 --GLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQP--- 1054
RC + + LD N C W EV D S P
Sbjct: 1331 GSQRRCVSNESQSLDD--------------NLGVC---------WQEVGADLVCSHPRLD 1367
Query: 1055 ---------CFHG-------GTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHH 1098
C +G C A +C+ P S P GF +
Sbjct: 1368 RQATYTECCCLYGEAWGMDCALCPAQDSDDFEALCNV---LRPPAYSPPRPG-GFGLPYE 1423
Query: 1099 GGLCLPSPKPGFPPRCACLSGYGGPDCLTPPA-PKGCGPPSPCLYNGSCSETTGLGGPGF 1157
G L P G P GP+ PPA P PP P GP
Sbjct: 1424 YGPDLGPPYQGLP---------YGPELYPPPALPYDPYPPPP--------------GPFA 1460
Query: 1158 RCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWD--GGDCSLGVPDPWKGCP 1215
R P+ + PR P + G G+ A GPG W D P+P +
Sbjct: 1461 RREAPYGA--PRFDMPDFEDDGGPYGESEAPAP-PGPGTRWPYRSRDTRRSFPEPEEPPE 1517
Query: 1216 SHSRCWLLFRDGQCHPQCDSEEC-LFDG 1242
S L + + + ++EEC + DG
Sbjct: 1518 GGSYAGSL---AEPYEELEAEECGILDG 1542
Score = 263 bits (672), Expect = 1e-69
Identities = 251/840 (29%), Positives = 337/840 (40%), Gaps = 165/840 (19%)
Query: 85 PAPLGLPSSPSPLTPSFLCTCLP--GFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQ 142
P P P P P P++ +P G + CQ P C GRC + SG
Sbjct: 518 PDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRN------PQVCGP-GRCISRPSGYT- 569
Query: 143 CSCMPGWT----GEQCQLRDFCSA--NPCVNGGVCLATYPQIQCHCPPGFEG--HACE-R 193
C+C G+ G +C D C PC G C + +C C PGF A E
Sbjct: 570 CACDSGFRLSPQGTRCIDVDECRRVPPPCAPGR-CENSPGSFRCVCGPGFRAGPRAAECL 628
Query: 194 DVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQE----GPRCELRAGPCPPRGCSNGGTC 249
DV+EC + P PC G C NT GSF C+CP G + G C+ G G C
Sbjct: 629 DVDECHRVPPPCDLGR-CENTPGSFLCVCPAGYQAAPHGASCQDVDECTQSPGLCGRGAC 687
Query: 250 QLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNG-GTCQDGLDTYTCLCPETWT- 307
+ +P +F C+CP GF G CE + D C G G C + ++ C CP +
Sbjct: 688 KNLP---GSFR-CVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRS 743
Query: 308 ---GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDCI 360
G C +DVDEC + PP C G C+N+ GSF CVC G+ G+ CE+ +D+C
Sbjct: 744 RGPGAPC-QDVDEC-ARSPPPCTYG-RCENTEGSFQCVCPMGFQPNTAGSECED-VDECE 799
Query: 361 AATCAPGSTCIDRVGSFSC-LCPPGRT--GLLCHLEDMCLS--QPCHGDAQCSTNPLTGS 415
PG C++ GSF C CP G C D C S PC C+ GS
Sbjct: 800 NHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTE--GS 857
Query: 416 TLCLCQPGYSGPTCHQ----DLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT--- 468
C C PGY P+ D++ECL C G CLNT GSF C C PGY
Sbjct: 858 FRCSCAPGYRAPSGRPGPCADVNECLEGDF----CFPHGECLNTDGSFACTCAPGYRPGP 913
Query: 469 -GSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPG------LEGQLCEVETNECASAP 521
G+ C D +EC + C + +F C+CPPG L L E E A
Sbjct: 914 RGASC-LDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCLDVDECRERGPAL 972
Query: 522 CLNHADCHDLLNGFQCI--CLPGF----SGTRCEEDIDECRS-SPCANGGQ-CQDQPGAF 573
C + C + ++C+ C PG+ GT C+ D+DEC+ P G Q C++ PG++
Sbjct: 973 CGSQR-CENSPGSYRCVRDCDPGYHAGPEGT-CD-DVDECQEYGPEICGAQRCENTPGSY 1029
Query: 574 HCK--CLPGFE---GPRCQTEVDECLSDP-CPVGASCLDLPGAFFCLCPSGFTGQLCEVP 627
C C PG++ G CQ +VDEC + C A C +LPG+F CLC G+ G
Sbjct: 1030 RCTPACDPGYQPTPGGGCQ-DVDECRNRSFCGAHAVCQNLPGSFQCLCDQGYEGARDGRH 1088
Query: 628 LCAPNLCQPKQ------ICKDQKDKANCLCPDG-------SPGCAPPEDNCTCHHGH--- 671
N C+ Q +C++ + C+CP+ + C PP + G
Sbjct: 1089 CVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAGTFPGSQPQ 1148
Query: 672 -----------------------------CQRSSCVCDVGW------------TGPECEA 690
R C D T EC
Sbjct: 1149 APASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARNVTWQECCC 1208
Query: 691 ELGGCISAPCAHGGTCYPQPSGYNCTCP--TGYTGPTCSEEMT------------ACHSG 736
+G + C + + Y CP GY P+ + C SG
Sbjct: 1209 TVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSG 1268
Query: 737 PCLN---GGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLC 793
C+N G SC S G YY T +C + + P GG CVN G++ C C
Sbjct: 1269 VCVNTAPGYSCYCSNGYYYHT-----QRLECIDNDECADEEPACEGGRCVNTVGSYHCTC 1323
Score = 237 bits (604), Expect = 1e-61
Identities = 229/839 (27%), Positives = 333/839 (39%), Gaps = 193/839 (23%)
Query: 289 GTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGW- 347
G C G + C EDVDEC T G C++G C N+ G + CVC G+
Sbjct: 342 GPCPTGFERVNGSC----------EDVDECATGG--RCQHG-ECANTRGGYTCVCPDGFL 388
Query: 348 ---GGTSC------EENLDDCIAATCAPGST------------CIDRVGSF---SC-LCP 382
+SC E C G + C RVG C LCP
Sbjct: 389 LDSSRSSCISQHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAWGRGCQLCP 448
Query: 383 P-GRTGLLCHLEDMCLSQPCH----GDAQCSTNPL------------------------- 412
P G G ++C + P + D + +T PL
Sbjct: 449 PFGSEGF----REICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAGF 504
Query: 413 -----------------TGSTLCLCQ-PGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLN 454
G L L P ++GP + M Q+ P C G C++
Sbjct: 505 LPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPG-RCIS 563
Query: 455 TPGSFNCLCPPGYT----GSRCEADHNEC--LSQPCHPGSTCLDLLATFHCLCPPGLEG- 507
P + C C G+ G+RC D +EC + PC PG C + +F C+C PG
Sbjct: 564 RPSGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCAPGR-CENSPGSFRCVCGPGFRAG 621
Query: 508 ----QLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFS----GTRCEEDIDECRSSP 559
+ +V+ PC + C + F C+C G+ G C+ D+DEC SP
Sbjct: 622 PRAAECLDVDECHRVPPPC-DLGRCENTPGSFLCVCPAGYQAAPHGASCQ-DVDECTQSP 679
Query: 560 CANG-GQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVG-ASCLDLPGAFFCLCPS 617
G G C++ PG+F C C GF G C+ +VDEC +P P G C + G+F C CP+
Sbjct: 680 GLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPA 739
Query: 618 GFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRS-- 675
GF + P C+D + A +PP C +G C+ +
Sbjct: 740 GFRSR------------GPGAPCQDVDECAR----------SPP----PCTYGRCENTEG 773
Query: 676 --SCVCDVGW----TGPECEAELGGCISAPCAHGGTCYPQPSGYNC-TCPTGY--TGPTC 726
CVC +G+ G ECE ++ C + G C P + C TCP+G+ C
Sbjct: 774 SFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRC 832
Query: 727 SEEMTACHSG--PCLNGGSCNPSPGGYYCTCPPSHTGPQ-----CQTSTDYCVSAPCFNG 779
+ ++ C SG PC G C + G + C+C P + P C + CF
Sbjct: 833 T-DVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPH 891
Query: 780 GTCVNRPGTFSCLCAMGFQ-GPRCEGKLR-PSCADSPCRNRATCQDSPQGPRCLCPTGYT 837
G C+N G+F+C CA G++ GPR L C++ C ++ C+CP G+
Sbjct: 892 GECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHR 951
Query: 838 GG----SCQTLMDLCAQKPCPRNSHCLQTGP-SFHCL--CLQGW-TGP--LCNLPLSSCQ 887
G SC + + + P S + P S+ C+ C G+ GP C+ + CQ
Sbjct: 952 AGPDLASCLDVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCD-DVDECQ 1010
Query: 888 KAALSQGIDVSSLCHNGGLCVDSGPSYFC--HCPPGFQ---GSLCQDHVNPCESRP-CQN 941
+ +C C ++ SY C C PG+Q G CQD V+ C +R C
Sbjct: 1011 EYG-------PEIC-GAQRCENTPGSYRCTPACDPGYQPTPGGGCQD-VDECRNRSFCGA 1061
Query: 942 GATCMAQPSGYLCQCAPGY----DGQNCSKELDACQS-QPCHNHGTCTPKPGGFHCACP 995
A C P + C C GY DG++C +++ C++ Q C G F C CP
Sbjct: 1062 HAVCQNLPGSFQCLCDQGYEGARDGRHC-VDVNECETLQGVCGAALCENVEGSFLCVCP 1119
Score = 234 bits (597), Expect = 6e-61
Identities = 301/1140 (26%), Positives = 408/1140 (35%), Gaps = 265/1140 (23%)
Query: 288 GGTCQD---GLDTYTCLCPETWTGWD------CSEDVDECETQGPPHCRNGGTCQNSAGS 338
GG C GL T C W CSE + E P G C
Sbjct: 295 GGECASPLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPD----GPCPTGFER 350
Query: 339 FHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLS 398
+ C E++D+C C + G ++C+CP G LL C+S
Sbjct: 351 VNGSC----------EDVDECATGGRCQHGECANTRGGYTCVCPDG--FLLDSSRSSCIS 398
Query: 399 Q--------PCH---GDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCE 447
Q PC D CS L T +C G +G C
Sbjct: 399 QHVISEAKGPCFRVLRDGGCSLPILRNITKQICCCSRVGKAW----------GRGCQLCP 448
Query: 448 HGGSCLNTPGSFNCLCP--PGYTGSRCEADHNE----------CLSQPCHPGST---CLD 492
GS F +CP PGY S + +N LSQP +T
Sbjct: 449 PFGS-----EGFREICPAGPGYHYSASDLRYNTRPLGQEPPRVSLSQPRTLPATSRPSAG 503
Query: 493 LLATFHCLCP---------PGLE--------------------GQLCEVETNECASAPCL 523
L T H L P PG E +C+ C C+
Sbjct: 504 FLPT-HRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCI 562
Query: 524 NHADCHDLLNGFQCICLPGF----SGTRCEEDIDECR--SSPCANGGQCQDQPGAFHCKC 577
+ +G+ C C GF GTRC D+DECR PCA G+C++ PG+F C C
Sbjct: 563 SRP------SGYTCACDSGFRLSPQGTRC-IDVDECRRVPPPCA-PGRCENSPGSFRCVC 614
Query: 578 LPGFE-GPRCQ--TEVDEC--LSDPCPVGASCLDLPGAFFCLCPSGFT----GQLC-EVP 627
PGF GPR +VDEC + PC +G C + PG+F C+CP+G+ G C +V
Sbjct: 615 GPGFRAGPRAAECLDVDECHRVPPPCDLG-RCENTPGSFLCVCPAGYQAAPHGASCQDVD 673
Query: 628 LC--APNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTG 685
C +P LC + CK+ C+CP G+ G
Sbjct: 674 ECTQSPGLC-GRGACKNLPGSFRCVCP----------------------------AGFRG 704
Query: 686 PECEAELGGCISAPCAHG-GTCYPQPSGYNCTCPTGY----TGPTCSEEMTACHSGPCLN 740
CE ++ C P G G C ++C CP G+ G C + S P
Sbjct: 705 SACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCT 764
Query: 741 GGSCNPSPGGYYCTCP----PSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSC-LCAM 795
G C + G + C CP P+ G +C+ D C + G CVN PG+F C C
Sbjct: 765 YGRCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNSPGSFQCRTCPS 823
Query: 796 G--FQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTG-----GSCQTLMDLC 848
G RC S PC C ++ RC C GY G C + +
Sbjct: 824 GHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECL 883
Query: 849 AQKPCPRNSHCLQTGPSFHCLCLQGW----TGPLCNLPLSSCQKAALSQGIDVSSLCHNG 904
C + CL T SF C C G+ G C L + C + L Q
Sbjct: 884 EGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASC-LDVDECSEEDLCQ----------S 932
Query: 905 GLCVDSGPSYFCHCPPGFQG----SLCQDHVNPCESR-PCQNGA-TCMAQPSGYLC--QC 956
G+C ++ S+ C CPPG + + C D V+ C R P G+ C P Y C C
Sbjct: 933 GICTNTDGSFECICPPGHRAGPDLASCLD-VDECRERGPALCGSQRCENSPGSYRCVRDC 991
Query: 957 APGYDG--QNCSKELDACQSQPCHNHGT--CTPKPGGFHC--ACPPGF---VGLRCEGDV 1007
PGY + ++D CQ G C PG + C AC PG+ G C+ DV
Sbjct: 992 DPGYHAGPEGTCDDVDECQEYGPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQ-DV 1050
Query: 1008 DECLDQPCHPTGTAACHSLANAFYCQCLPGH----TGQWCEVEIDPCHS-QPCFHGGTCE 1062
DEC ++ A C +L +F C C G+ G+ C V+++ C + Q CE
Sbjct: 1051 DECRNR-SFCGAHAVCQNLPGSFQCLCDQGYEGARDGRHC-VDVNECETLQGVCGAALCE 1108
Query: 1063 ATAGSPLGFICHCPKG---FEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSG 1119
GS F+C CP F+ T G C+ PPR +
Sbjct: 1109 NVEGS---FLCVCPNSPEEFDPMT----------------GRCV-------PPRTSA-GT 1141
Query: 1120 YGGPDCLTPPAP-KGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGP-RCQKPGAKG 1177
+ G P +P PP P L + G G G R C + P C A+
Sbjct: 1142 FPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSG-RRECYFDTAAPDACDNILARN 1200
Query: 1178 CEGRSGDGACDAGCSGPGGNWDGG----DCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQC 1233
+ C C G W G C ++ H R +L G +
Sbjct: 1201 VTWQE----C---CCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLA-PSGDLSLRR 1252
Query: 1234 DSEEC-LFDGYDCETPPA--CTPAYDQYCHD--HFHNGHCE----KGCNTAECGWDGGDC 1284
D +EC LF C++ P Y YC + ++H E C E +GG C
Sbjct: 1253 DVDECQLFRDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRC 1312
Score = 176 bits (446), Expect = 2e-43
Identities = 264/1028 (25%), Positives = 356/1028 (34%), Gaps = 197/1028 (19%)
Query: 28 CGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAP 87
C P C G C +L G C C GF G C+ ++ C A P P
Sbjct: 675 CTQSPGLCGRGA-CKNLP-GSFRCVCPAGFRGSACE-----EDVDEC-------AQEPPP 720
Query: 88 LGLPSSPSPLTPSFLCTCLPGFT----GERCQAKLEDPCPPSFCSKRGRCHIQASGRPQC 143
G P SF C C GF G CQ E P C+ GRC G QC
Sbjct: 721 CG-PGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTY-GRCE-NTEGSFQC 777
Query: 144 SC----MPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCH-CPPGFEGHACE-RDVNE 197
C P G +C+ D C + G C+ + QC CP G H DV+E
Sbjct: 778 VCPMGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDE 837
Query: 198 CFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPP-RGCSNGGTCQLMPE-- 254
C PC C NT GSF+C C G P R GPC C G C E
Sbjct: 838 CSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSG--RPGPCADVNECLEGDFCFPHGECL 895
Query: 255 -KDSTFHLCLCPPGFI----GPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETW-TG 308
D +F C C PG+ G C ++ D C G C + ++ C+CP G
Sbjct: 896 NTDGSF-ACTCAPGYRPGPRGASC-LDVDECSEEDLCQSGICTNTDGSFECICPPGHRAG 953
Query: 309 WDCSE--DVDECETQGPPHCRNGGTCQNSAGSFHCV--CVSGW--GGTSCEENLDDC--I 360
D + DVDEC +GP C C+NS GS+ CV C G+ G +++D+C
Sbjct: 954 PDLASCLDVDECRERGPALC-GSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEY 1012
Query: 361 AATCAPGSTCIDRVGSFSCL--CPPG---RTGLLCHLEDMCLSQP-CHGDAQCSTNPLTG 414
C + GS+ C C PG G C D C ++ C A C P G
Sbjct: 1013 GPEICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLP--G 1070
Query: 415 STLCLCQPGYSGPTCHQ---DLDEC--LMAQQGPSPCEHGGSCLNTPGSFNCLC------ 463
S CLC GY G + D++EC L G + CE N GSF C+C
Sbjct: 1071 SFQCLCDQGYEGARDGRHCVDVNECETLQGVCGAALCE------NVEGSFLCVCPNSPEE 1124
Query: 464 ---------PPG-----YTGSRCEAD-----------------------------HNECL 480
PP + GS+ +A EC
Sbjct: 1125 FDPMTGRCVPPRTSAGTFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECY 1184
Query: 481 SQPCHPGSTCLDLLATF----HCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQ 536
P + C ++LA C C G EG +C + G+
Sbjct: 1185 FDTAAPDA-CDNILARNVTWQECCCTVG-EGWGSGCRIQQCPGTETAEYQSLCPHGRGY- 1241
Query: 537 CICLPGFSGTRCEEDIDEC---RSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEV--- 590
L D+DEC R C +G PG + C C G+ + E
Sbjct: 1242 ---LAPSGDLSLRRDVDECQLFRDQVCKSGVCVNTAPG-YSCYCSNGYYYHTQRLECIDN 1297
Query: 591 DECLSD-PCPVGASCLDLPGAFFCLCPSGFTGQLCEVPL--------CAPNLCQPKQ--- 638
DEC + P G C++ G++ C C E PL C N Q
Sbjct: 1298 DECADEEPACEGGRCVNTVGSYHCTC---------EPPLVLDGSQRRCVSNESQSLDDNL 1348
Query: 639 -ICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCIS 697
+C Q+ A+ +C C C +G C + EA +
Sbjct: 1349 GVCW-QEVGADLVCSHPRLDRQATYTECCCLYGEAWGMDCALCPAQDSDDFEALCN--VL 1405
Query: 698 APCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPP 757
P A+ P+P G+ P Y GP GP L P P Y PP
Sbjct: 1406 RPPAYSP---PRPGGFGL--PYEY-GPDLGPPYQGLPYGPELY-----PPPALPYDPYPP 1454
Query: 758 SHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRN 817
GP + Y AP F+ + G + A GP P R+
Sbjct: 1455 P-PGPFARREAPY--GAPRFDMPDFEDDGGPYGESEAPAPPGPGTRW---------PYRS 1502
Query: 818 RATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCP-----RNSHCLQTGPSFHCLCLQ 872
R T + P+ Y G + +L A++ C N C++ F C C
Sbjct: 1503 RDTRRSFPEPEEPPEGGSYAGSLAEPYEELEAEE-CGILDGCTNGRCVRVPEGFTCRCFD 1561
Query: 873 GWTGPLCNLP---LSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQD 929
G+ + + ++ C +A + S LC N C+++ S+ C C PGF +
Sbjct: 1562 GYRLDMTRMACVDINECDEAEAA-----SPLCVNAR-CLNTDGSFRCICRPGFAPTHQPH 1615
Query: 930 HVNPCESR 937
H P R
Sbjct: 1616 HCAPARPR 1623
Score = 166 bits (420), Expect = 2e-40
Identities = 211/786 (26%), Positives = 281/786 (35%), Gaps = 178/786 (22%)
Query: 577 CLPGFEGPRCQTE-VDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQ 635
C GFE E VDEC + C + G + C+CP GF + + C
Sbjct: 344 CPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCVCPDGFLLD------SSRSSCI 397
Query: 636 PKQICKDQKDKANCLCPDGSPGCAPP------EDNCTCHH-GHCQRSSC-VCDVGWTGPE 687
+ + + K + DG GC+ P + C C G C +C G E
Sbjct: 398 SQHVISEAKGPCFRVLRDG--GCSLPILRNITKQICCCSRVGKAWGRGCQLCPP--FGSE 453
Query: 688 CEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEM------TACHSGPCLNG 741
E+ C + P H YN T P G P S T+ S L
Sbjct: 454 GFREI--CPAGPGYHYSA---SDLRYN-TRPLGQEPPRVSLSQPRTLPATSRPSAGFLPT 507
Query: 742 GSCNPSPG-------GYYCTCP--PSHTGPQCQTS---TDYCVSAPCFNG-GTCVNRPGT 788
P P G P P+ TGP+ S + C P G G C++RP
Sbjct: 508 HRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSG 567
Query: 789 FSCLCAMGF----QGPRCEG-----KLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGG 839
++C C GF QG RC ++ P CA C N SP RC+C G+ G
Sbjct: 568 YTCACDSGFRLSPQGTRCIDVDECRRVPPPCAPGRCEN------SPGSFRCVCGPGFRAG 621
Query: 840 SCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSS 899
PR + CL P C+L
Sbjct: 622 --------------PRAAECLDVDECHR-------VPPPCDL------------------ 642
Query: 900 LCHNGGLCVDSGPSYFCHCPPGFQ----GSLCQDHVNPCESRP--CQNGATCMAQPSGYL 953
G C ++ S+ C CP G+Q G+ CQD V+ C P C GA C P +
Sbjct: 643 -----GRCENTPGSFLCVCPAGYQAAPHGASCQD-VDECTQSPGLCGRGA-CKNLPGSFR 695
Query: 954 CQCAPGYDGQNCSKELDAC-QSQPCHNHGTCTPKPGGFHCACPPGF----VGLRCEGDVD 1008
C C G+ G C +++D C Q P G C G FHCACP GF G C+ DVD
Sbjct: 696 CVCPAGFRGSACEEDVDECAQEPPPCGPGRCDNTAGSFHCACPAGFRSRGPGAPCQ-DVD 754
Query: 1009 ECLDQPCHPTGTAACHSLANAFYCQC----LPGHTGQWCEVEIDPCHSQPCFHGGTCEAT 1064
EC P P C + +F C C P G CE ++D C + G C +
Sbjct: 755 ECARSP-PPCTYGRCENTEGSFQCVCPMGFQPNTAGSECE-DVDECENHLACPGQECVNS 812
Query: 1065 AGS------PLGFICHCPKGFEGPTCSHRAPSCGFH-HCHHGGLCLPSPKPGFPPRCACL 1117
GS P G H + + CS AP CG H HC + + F RC+C
Sbjct: 813 PGSFQCRTCPSGHHLHRGRCTDVDECSSGAPPCGPHGHC-------TNTEGSF--RCSCA 863
Query: 1118 SGYGGPDCLTPPAP--KGCGPPSPCLYNGSCSETTGLGGPGFRCSC-PHSSPGPRCQKPG 1174
GY P P C C +G C T G F C+C P PGPR G
Sbjct: 864 PGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDG----SFACTCAPGYRPGPR----G 915
Query: 1175 AK--GCEGRSGDGACDAG-CSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHP 1231
A + S + C +G C+ G+++ C P + P + C
Sbjct: 916 ASCLDVDECSEEDLCQSGICTNTDGSFE---CIC--PPGHRAGPDLASC----------- 959
Query: 1232 QCDSEECLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRPEDGDP 1291
D +EC G P C Q C + + C + C+ G C D
Sbjct: 960 -LDVDECRERG-----PALCG---SQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQ 1010
Query: 1292 EWGPSL 1297
E+GP +
Sbjct: 1011 EYGPEI 1016
Score = 38.9 bits (89), Expect = 0.051
Identities = 16/31 (51%), Positives = 18/31 (58%), Gaps = 3/31 (9%)
Query: 900 LCHNGGLCVDSGPSYFCHCPPGFQGSLCQDH 930
+CHNGG+CV C CPP F G CQ H
Sbjct: 156 ICHNGGVCVKPDR---CLCPPDFAGKFCQLH 183
Score = 38.9 bits (89), Expect = 0.051
Identities = 34/95 (35%), Positives = 42/95 (44%), Gaps = 17/95 (17%)
Query: 182 CPPGFE--GHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG----QEGPRC---- 231
CP GFE +CE DV+EC G C G C NT G + C+CP G C
Sbjct: 344 CPTGFERVNGSCE-DVDECATG-GRCQHG-ECANTRGGYTCVCPDGFLLDSSRSSCISQH 400
Query: 232 --ELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLC 264
GPC R +GG C L ++ T +C C
Sbjct: 401 VISEAKGPC-FRVLRDGG-CSLPILRNITKQICCC 433
Score = 37.7 bits (86), Expect = 0.11
Identities = 22/70 (31%), Positives = 28/70 (40%), Gaps = 14/70 (20%)
Query: 939 CQNGATCMAQPSGYLCQCAPGY----------DGQNCSKELDACQSQPCHNHGTCTPKPG 988
C NG C+ P G+ C+C GY D C +A + P + C G
Sbjct: 1543 CTNGR-CVRVPEGFTCRCFDGYRLDMTRMACVDINECD---EAEAASPLCVNARCLNTDG 1598
Query: 989 GFHCACPPGF 998
F C C PGF
Sbjct: 1599 SFRCICRPGF 1608
Score = 34.3 bits (77), Expect = 1.3
Identities = 38/151 (25%), Positives = 53/151 (35%), Gaps = 37/151 (24%)
Query: 143 CSCMPGWTGEQ-------CQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDV 195
C C PG T + C++R C C CL P + P +R V
Sbjct: 53 CRCCPGQTSRRSRCIRAFCRVRS-CQPKKCAGPQRCLNPVPAVPSPSPS-----VRKRQV 106
Query: 196 NECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEG-------PRCELRAGPCP---PRGCSN 245
+ +Q + + P G G P AG P P C N
Sbjct: 107 SLNWQP-------LTLQEARALLKRRRPRGPGGRGLLRRRPPQRAPAGKAPVLCPLICHN 159
Query: 246 GGTCQLMPEKDSTFHLCLCPPGFIGPDCEVN 276
GG C + P++ CLCPP F G C+++
Sbjct: 160 GGVC-VKPDR------CLCPPDFAGKFCQLH 183
Score = 33.1 bits (74), Expect = 2.8
Identities = 58/242 (23%), Positives = 73/242 (30%), Gaps = 59/242 (24%)
Query: 977 CHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTG----TAACHSLANAFYC 1032
CHN G C KP C CPP F G C+ H +G A L + Y
Sbjct: 157 CHNGGVCV-KPD--RCLCPPDFAGKFCQ----------LHSSGARPPAPAVPGLTRSVYT 203
Query: 1033 QCLPGHT----GQWCEVEIDPCHSQPC-------------FHGGTCEATAGSPLGFICHC 1075
L H G V + H Q + EA A +
Sbjct: 204 MPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERVSGPWEEADAEAVARAEAAARAEA 263
Query: 1076 PKGF-----EGPTCSHRAPSCGFHHCH---HGGLCLPSPKPGFPPRCACLSG----YGGP 1123
+ P + + GF +C GG C SP PG + C G +G
Sbjct: 264 AAPYTVLAQSAPREDGYSDASGFGYCFRELRGGEC-ASPLPGLRTQEVCCRGAGLAWGVH 322
Query: 1124 DCLTPPAPKG-----CGPPSPC-----LYNGSCSET--TGLGGPGFRCSCPHSSPGPRCQ 1171
DC G P PC NGSC + GG C ++ G C
Sbjct: 323 DCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTCV 382
Query: 1172 KP 1173
P
Sbjct: 383 CP 384
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 257 bits (657), Expect = 7e-68
Identities = 250/884 (28%), Positives = 321/884 (36%), Gaps = 215/884 (24%)
Query: 334 NSAGSFHCVCVSGWGGTSCEENLDD--------CIAATCAPG----------STCIDRVG 375
NS SF C+ + W GT+ NL+D + T ++C D +
Sbjct: 6 NSCLSFICLLLCHWIGTASPLNLEDPNVCSHWESYSVTVQESYPHPFDQIYYTSCTDILN 65
Query: 376 SFSCL-----------------------CPPG--RTGLLC--HLEDMCLSQPCHGDAQCS 408
F C C PG +G +C H D C+ C
Sbjct: 66 WFKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHGRC------- 118
Query: 409 TNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT 468
C C+PG+ G C D S C+ L P + C C G+
Sbjct: 119 ----IAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITGACHCAAGFR 174
Query: 469 GSRCE------ADHNECLSQ-PCHPGSTCLDLLATFHCLCPPGLEGQLCE------VETN 515
G RCE N+C + C G+TC + T C CPPG G CE
Sbjct: 175 GWRCEDRCEQGTYGNDCHQRCQCQNGATCDHV--TGECRCPPGYTGAFCEDLCPPGKHGP 232
Query: 516 ECAS-APCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECR-------SSPCANGGQCQ 567
+C PC N CH + +C C G+ GT C + E R C NGG C
Sbjct: 233 QCEQRCPCQNGGVCHHVTG--ECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCHNGGTCD 290
Query: 568 DQPGAFHCKCLPGFEGPRCQTEVDEC----------LSDPCPVGASCLDLPGAFFCLCPS 617
G C C PG+ G RCQ DEC + C G C + GA CLC +
Sbjct: 291 AATG--QCHCSPGYTGERCQ---DECPVGTYGVLCAETCQCVNGGKCYHVSGA--CLCEA 343
Query: 618 GFTGQLCEVPLCAPNL----CQPKQICKDQKD------KANCLCPDGSPG------CAPP 661
GF G+ CE LC L C + C + C C G G C+P
Sbjct: 344 GFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPG 403
Query: 662 ------EDNCTCHHG-HCQ--RSSCVCDVGWTGPECE--AELG----GCIS-APCAHGGT 705
+ C+C +G C C C G+ G +C LG C S C +
Sbjct: 404 FYGEACQQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAV 463
Query: 706 CYPQPSGYNCTCPTGYTGPTCSEEMTACHSG----------PCLNGGSCNPSPGGYYCTC 755
C P +CTC G+ G CS C SG CLNGG+CN G CTC
Sbjct: 464 CSPVDG--SCTCKAGWHGVDCS---IRCPSGTWGFGCNLTCQCLNGGACNTLDG--TCTC 516
Query: 756 PPSHTGPQCQ-TSTDYCVSAPCFNGGTCVN----RPGTFSCLCAMGFQGPRC-----EGK 805
P G +C+ D C C + P T C C G+ G C EG+
Sbjct: 517 APGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGR 576
Query: 806 LRPSCA-DSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMD------LCAQKPCPRNSH 858
P+C+ C+N A+C SP C C G+ G +CQ + C+Q CP+ H
Sbjct: 577 WGPNCSLPCYCKNGASC--SPDDGICECAPGFRGTTCQRICSPGFYGHRCSQ-TCPQCVH 633
Query: 859 CLQTGPSFH----CLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSY 914
+GP H C CL G+TG LCN C + C N G C S
Sbjct: 634 --SSGPCHHITGLCDCLPGFTGALCN---EVCPSGRFGKNCAGICTCTNNGTCNPIDRS- 687
Query: 915 FCHCPPGFQGSLCQDHVNPCESRP-------CQNGATCMAQPSGYLCQCAPGYDGQNCSK 967
C C PG+ GS C P P C NGA C A C+C PG+ G C++
Sbjct: 688 -CQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGE--CKCTPGWTGLYCTQ 744
Query: 968 EL-------DACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGT 1020
D C N C G C C GF+G CE Q C P+GT
Sbjct: 745 RCPLGFYGKDCALICQCQNGADCDHISG--QCTCRTGFMGRHCE--------QKC-PSGT 793
Query: 1021 --AACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCE 1062
C + C CL T C+ C+ P + G C+
Sbjct: 794 YGYGCRQI-----CDCLNNST---CDHITGTCYCSPGWKGARCD 829
Score = 254 bits (648), Expect = 8e-67
Identities = 259/930 (27%), Positives = 323/930 (34%), Gaps = 314/930 (33%)
Query: 46 LGQGTCQCAPGFLGETCQ-------FPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLT 98
+ TCQC PG+ G C + C + C+NG C +P+T
Sbjct: 119 IAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALC--------------NPIT 164
Query: 99 PSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQAS---GRPQCSCMPGWTGEQCQ 155
+ C C GF G RC+ + E + C +R +C A+ +C C PG+TG C+
Sbjct: 165 GA--CHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATCDHVTGECRCPPGYTGAFCE 222
Query: 156 LRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTL 215
D C PPG G CE+ C PC G CH+
Sbjct: 223 --DLC----------------------PPGKHGPQCEQ---RC-----PCQNGGVCHHVT 250
Query: 216 GSFQCLCPVGQEGPRCELRAGPCPPR----------GCSNGGTCQLMPEKDSTFHLCLCP 265
G +C CP G G C PCP C NGGTC D+ C C
Sbjct: 251 G--ECSCPSGWMGTVC---GQPCPEGRFGKNCSQECQCHNGGTC------DAATGQCHCS 299
Query: 266 PGFIGPDCEVNPDNC----------VSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDV 315
PG+ G C+ D C + QC NGG C + CLC + G C +
Sbjct: 300 PGYTGERCQ---DECPVGTYGVLCAETCQCVNGGKCYH--VSGACLCEAGFAGERCEARL 354
Query: 316 -------DECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEE-------------- 354
+C+ + P H N +C +G C C GW G C E
Sbjct: 355 CPEGLYGIKCDKRCPCHLENTHSCHPMSG--ECACKPGWSGLYCNETCSPGFYGEACQQI 412
Query: 355 ----NLDDCIA----ATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQ 406
N DC + TCAPG ID S CP G G+ C C C DA
Sbjct: 413 CSCQNGADCDSVTGKCTCAPGFKGID----CSTPCPLGTYGINC--SSRC---GCKNDAV 463
Query: 407 CSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQG-----PSPCEHGGSCLNTPGSFNC 461
CS P+ GS C C+ G+ G C C G C +GG+C G+ C
Sbjct: 464 CS--PVDGS--CTCKAGWHGVDCS---IRCPSGTWGFGCNLTCQCLNGGACNTLDGT--C 514
Query: 462 LCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAP 521
C PG+ G +CE PC G+ L+ C
Sbjct: 515 TCAPGWRGEKCEL--------PCQDGTYGLNCAERCDC---------------------- 544
Query: 522 CLNHAD-CHDLLNGFQCICLPGFSGTRCEEDIDECRSSP-------CANGGQCQDQPGAF 573
+HAD CH C CLPG+SG C+ E R P C NG C G
Sbjct: 545 --SHADGCHPTTG--HCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGIC 600
Query: 574 HCK-----------CLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQ 622
C C PGF G RC +C+ P C + G C C GFTG
Sbjct: 601 ECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGP----CHHITG--LCDCLPGFTGA 654
Query: 623 LCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPEDNCTC-HHGHCQ--RSSC 677
LC N +CP G G CA CTC ++G C SC
Sbjct: 655 LC-----------------------NEVCPSGRFGKNCA---GICTCTNNGTCNPIDRSC 688
Query: 678 VCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGP 737
C GW G +C QP CP + GP C CH+G
Sbjct: 689 QCYPGWIGSDCS-------------------QP------CPPAHWGPNCIHTCN-CHNGA 722
Query: 738 CLNG--GSCNPSPG--GYYCT--CPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSC 791
+ G C +PG G YCT CP G C + C NG C + G C
Sbjct: 723 FCSAYDGECKCTPGWTGLYCTQRCPLGFYGKDC------ALICQCQNGADCDHISG--QC 774
Query: 792 LCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQK 851
C GF G CE K CP+G G C+ + D
Sbjct: 775 TCRTGFMGRHCEQK--------------------------CPSGTYGYGCRQICD----- 803
Query: 852 PCPRNSHCLQ-TGPSFHCLCLQGWTGPLCN 880
C NS C TG C C GW G C+
Sbjct: 804 -CLNNSTCDHITGT---CYCSPGWKGARCD 829
Score = 241 bits (616), Expect = 4e-63
Identities = 247/863 (28%), Positives = 312/863 (36%), Gaps = 232/863 (26%)
Query: 420 CQPGY--SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTG----SRCE 473
C PG+ SG C + C C HG C+ P + C C PG+ G S C+
Sbjct: 94 CCPGFYESGEMC---VPHCA------DKCVHG-RCI-APNT--CQCEPGWGGTNCSSACD 140
Query: 474 ADH--NECLSQ-PCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHD 530
DH C S+ C G+ C + HC G G CE + C N DCH
Sbjct: 141 GDHWGPHCTSRCQCKNGALCNPITGACHCAA--GFRGWRCE---DRCEQGTYGN--DCHQ 193
Query: 531 LLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEV 590
+C C +G C+ ECR P G C+D C PG GP+C+
Sbjct: 194 -----RCQCQ---NGATCDHVTGECRCPPGYTGAFCEDL-------CPPGKHGPQCEQRC 238
Query: 591 DECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCL 650
PC G C + G C CPSG+ G +C P
Sbjct: 239 ------PCQNGGVCHHVTGE--CSCPSGWMGTVCGQP----------------------- 267
Query: 651 CPDGSPGCAPPEDNCTCHHGH-CQRSS--CVCDVGWTGPECEAELG----GCISAP---C 700
CP+G G ++ C CH+G C ++ C C G+TG C+ E G + A C
Sbjct: 268 CPEGRFGKNCSQE-CQCHNGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQC 326
Query: 701 AHGGTCYPQPSGYNCTCPTGYTGPTCS---------------------EEMTACH--SGP 737
+GG CY C C G+ G C E +CH SG
Sbjct: 327 VNGGKCYHVSGA--CLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGE 384
Query: 738 CLNGGSCNPSPGGYYC--TCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAM 795
C +C P G YC TC P G CQ C NG C + G C CA
Sbjct: 385 C----ACKPGWSGLYCNETCSPGFYGEACQQICS------CQNGADCDSVTG--KCTCAP 432
Query: 796 GFQGPRCE-----GKLRPSCADS-PCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCA 849
GF+G C G +C+ C+N A C SP C C G+ G C C
Sbjct: 433 GFKGIDCSTPCPLGTYGINCSSRCGCKNDAVC--SPVDGSCTCKAGWHGVDCSIR---CP 487
Query: 850 QKP----CPRNSHCLQTGP----SFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLC 901
C CL G C C GW G C LP CQ + G++ + C
Sbjct: 488 SGTWGFGCNLTCQCLNGGACNTLDGTCTCAPGWRGEKCELP---CQDG--TYGLNCAERC 542
Query: 902 ---HNGGLCVDSGPSYFCHCPPGFQGSLC-----QDHVNPCESRPC--QNGATCMAQPSG 951
H G +G C C PG+ G C + P S PC +NGA+C P
Sbjct: 543 DCSHADGCHPTTG---HCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASC--SPDD 597
Query: 952 YLCQCAPGYDG-------------QNCSKELDAC--QSQPCHN-HGTCTPKPG--GFHC- 992
+C+CAPG+ G CS+ C S PCH+ G C PG G C
Sbjct: 598 GICECAPGFRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCN 657
Query: 993 -ACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCH 1051
CP G G C G C T C+ + + CQC PG G C P H
Sbjct: 658 EVCPSGRFGKNCAGI--------CTCTNNGTCNPIDRS--CQCYPGWIGSDCSQPCPPAH 707
Query: 1052 SQP-------CFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFH--------HC 1096
P C +G C A G C C G+ G C+ R P GF+ C
Sbjct: 708 WGPNCIHTCNCHNGAFCSAYDGE-----CKCTPGWTGLYCTQRCP-LGFYGKDCALICQC 761
Query: 1097 HHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKG-----CGPPSPCLYNGSCSETTG 1151
+G C +C C +G+ G C P G C CL N +C TG
Sbjct: 762 QNGADC-----DHISGQCTCRTGFMGRHC-EQKCPSGTYGYGCRQICDCLNNSTCDHITG 815
Query: 1152 LGGPGFRCSCPHSSPGPRCQKPG 1174
C C G RC + G
Sbjct: 816 ------TCYCSPGWKGARCDQAG 832
Score = 240 bits (613), Expect = 9e-63
Identities = 230/799 (28%), Positives = 296/799 (37%), Gaps = 194/799 (24%)
Query: 324 PHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLD------DCIA-ATCAPGSTCIDRVGS 376
PHC + C C GWGGT+C D C + C G+ C G
Sbjct: 107 PHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQCKNGALCNPITG- 165
Query: 377 FSCLCPPGRTGLLCHLEDMC----LSQPCHGDAQC----STNPLTGSTLCLCQPGYSGPT 428
+C C G G C ED C CH QC + + +TG C C PGY+G
Sbjct: 166 -ACHCAAGFRGWRC--EDRCEQGTYGNDCHQRCQCQNGATCDHVTGE--CRCPPGYTGAF 220
Query: 429 CHQDLDECLMAQQGPS-----PCEHGGSCLNTPGSFNCLCPPGYTGSRC-----EADHNE 478
C D C + GP PC++GG C + G C CP G+ G+ C E +
Sbjct: 221 CE---DLCPPGKHGPQCEQRCPCQNGGVCHHVTG--ECSCPSGWMGTVCGQPCPEGRFGK 275
Query: 479 CLSQ--PCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNE------CA-SAPCLNHADCH 529
SQ CH G TC AT C C PG G+ C+ E CA + C+N C+
Sbjct: 276 NCSQECQCHNGGTC--DAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCY 333
Query: 530 DLLNGFQCICLPGFSGTRCEEDI-------DEC-RSSPC---------ANGGQCQDQPG- 571
+ C+C GF+G RCE + +C + PC G+C +PG
Sbjct: 334 HVSGA--CLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGW 391
Query: 572 -AFHCK--CLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPL 628
+C C PGF G CQ C GA C + G C C GF G C P
Sbjct: 392 SGLYCNETCSPGFYGEACQQICS------CQNGADCDSVTGK--CTCAPGFKGIDCSTPC 443
Query: 629 --------CAPNL-CQPKQICKDQKDKANC-----------LCPDGSPGCAPPEDNCTC- 667
C+ C+ +C C CP G+ G N TC
Sbjct: 444 PLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFG---CNLTCQ 500
Query: 668 --HHGHCQR--SSCVCDVGWTGPECEAE-------LGGCISAPCAHGGTCYPQPSGYNCT 716
+ G C +C C GW G +CE L C+H C+P +C
Sbjct: 501 CLNGGACNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAERCDCSHADGCHPTTG--HCR 558
Query: 717 CPTGYTGPTCSEEMTACHSGP-------CLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTD 769
C G++G C GP C NG SC+P G C C P G CQ
Sbjct: 559 CLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDG--ICECAPGFRGTTCQR--- 613
Query: 770 YCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADS--PCRN---RATCQDS 824
+C+ GF G RC + P C S PC + C
Sbjct: 614 ----------------------ICSPGFYGHRC-SQTCPQCVHSSGPCHHITGLCDCLPG 650
Query: 825 PQGPRC--LCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLP 882
G C +CP+G G +C +C C N C S C C GW G C+ P
Sbjct: 651 FTGALCNEVCPSGRFGKNC---AGICT---CTNNGTCNPIDRS--CQCYPGWIGSDCSQP 702
Query: 883 LSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLC----------QDHVN 932
C A + CHNG C S C C PG+ G C +D
Sbjct: 703 ---CPPAHWGPNCIHTCNCHNGAFC--SAYDGECKCTPGWTGLYCTQRCPLGFYGKDCAL 757
Query: 933 PCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDA------C-QSQPCHNHGTCTP 985
C+ CQNGA C SG C C G+ G++C ++ + C Q C N+ TC
Sbjct: 758 ICQ---CQNGADC-DHISGQ-CTCRTGFMGRHCEQKCPSGTYGYGCRQICDCLNNSTCDH 812
Query: 986 KPGGFHCACPPGFVGLRCE 1004
G C C PG+ G RC+
Sbjct: 813 ITG--TCYCSPGWKGARCD 829
Score = 229 bits (583), Expect = 3e-59
Identities = 240/849 (28%), Positives = 307/849 (36%), Gaps = 203/849 (23%)
Query: 525 HADCHDLLNGFQCI-----------------------CLPGF--SGTRC-EEDIDECRSS 558
+ C D+LN F+C C PGF SG C D+C
Sbjct: 57 YTSCTDILNWFKCTRHRVSYRTAYRHGEKTMYRRKSQCCPGFYESGEMCVPHCADKCVHG 116
Query: 559 PCANGGQCQDQPGAFHCKCLPGFE----GPRCQTEVDECLSDPCPVGASCLDLPGAFFCL 614
C CQ +PG C + GP C + C GA C + GA C
Sbjct: 117 RCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQ------CKNGALCNPITGA--CH 168
Query: 615 CPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQR 674
C +GF G CE + C+ D + C C +G+ C C C G+
Sbjct: 169 CAAGFRGWRCE------DRCEQGTYGNDCHQR--CQCQNGAT-CDHVTGECRCPPGYTGA 219
Query: 675 -SSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTAC 733
+C G GP+CE PC +GG C+ C+CP+G+ G C +
Sbjct: 220 FCEDLCPPGKHGPQCEQR------CPCQNGGVCHHVTG--ECSCPSGWMGTVCGQPCPEG 271
Query: 734 HSG-------PCLNGGSCNPSPGGYYCTCPPSHTGPQCQ------TSTDYCV-SAPCFNG 779
G C NGG+C+ + G C C P +TG +CQ T C + C NG
Sbjct: 272 RFGKNCSQECQCHNGGTCDAATG--QCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNG 329
Query: 780 GTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGG 839
G C + G +CLC GF G RCE + LCP G G
Sbjct: 330 GKCYHVSG--ACLCEAGFAGERCEAR-------------------------LCPEGLYGI 362
Query: 840 SCQTLMDLCAQKPCP---RNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGID 896
C K CP N+H S C C GW+G CN +C +
Sbjct: 363 KC--------DKRCPCHLENTHSCHP-MSGECACKPGWSGLYCN---ETCSPGFYGEACQ 410
Query: 897 VSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQ------DHVNPCESR-PCQNGATCMAQP 949
C NG C + C C PGF+G C + C SR C+N A C P
Sbjct: 411 QICSCQNGADC--DSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVC--SP 466
Query: 950 SGYLCQCAPGYDGQNCSKELDA----------CQSQPCHNHGTCTPKPGGFHCACPPGFV 999
C C G+ G +CS + CQ C N G C G C C PG+
Sbjct: 467 VDGSCTCKAGWHGVDCSIRCPSGTWGFGCNLTCQ---CLNGGACNTLDG--TCTCAPGWR 521
Query: 1000 GLRCE-----GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWC-----EVEIDP 1049
G +CE G + C + CH +C+CLPG +G C E P
Sbjct: 522 GEKCELPCQDGTYGLNCAERCDCSHADGCHPTTG--HCRCLPGWSGVHCDSVCAEGRWGP 579
Query: 1050 CHSQPCF--HGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGF--HHCHHG-GLCLP 1104
S PC+ +G +C SP IC C GF G TC R S GF H C C+
Sbjct: 580 NCSLPCYCKNGASC-----SPDDGICECAPGFRGTTC-QRICSPGFYGHRCSQTCPQCVH 633
Query: 1105 SPKP--GFPPRCACLSGYGGPDC--LTPPA--PKGCGPPSPCLYNGSCSETTGL-----G 1153
S P C CL G+ G C + P K C C NG+C+ G
Sbjct: 634 SSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTCTNNGTCNPIDRSCQCYPG 693
Query: 1154 GPGFRCS--CPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPW 1211
G CS CP + GP C C +G A CS G C+ G W
Sbjct: 694 WIGSDCSQPCPPAHWGPNC----IHTCNCHNG-----AFCSAYDGEC---KCTPG----W 737
Query: 1212 KGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCE-TPPACTPAYDQYCHDHFHNGHCEK 1270
G RC L F C C + +G DC+ CT C F HCE+
Sbjct: 738 TGLYCTQRCPLGFYGKDCALICQCQ----NGADCDHISGQCT------CRTGFMGRHCEQ 787
Query: 1271 GCNTAECGW 1279
C + G+
Sbjct: 788 KCPSGTYGY 796
Score = 219 bits (559), Expect = 2e-56
Identities = 211/741 (28%), Positives = 262/741 (35%), Gaps = 194/741 (26%)
Query: 35 CANGGTCLSLSLGQGTCQCAPGFLGETCQFPDP-------CQNAQLCQNGGSCQALLPAP 87
C NG TC ++ G C+C PG+ G C+ P C+ CQNGG C +
Sbjct: 197 CQNGATCDHVT---GECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGE- 252
Query: 88 LGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSF----CSKRGRCHIQAS---GR 140
C+C G+ G C PCP CS+ +CH +
Sbjct: 253 ---------------CSCPSGWMGTVCG----QPCPEGRFGKNCSQECQCHNGGTCDAAT 293
Query: 141 PQCSCMPGWTGEQCQLRDFCSAN----------PCVNGGVCLATYPQIQCHCPPGFEGHA 190
QC C PG+TGE+CQ D C CVNGG C + C C GF G
Sbjct: 294 GQCHCSPGYTGERCQ--DECPVGTYGVLCAETCQCVNGGKCY--HVSGACLCEAGFAGER 349
Query: 191 CERDVNECFQDPGPCPKGTSCH--NTLG----SFQCLCPVGQEGPRCELRAGP-CPPRGC 243
CE + C K CH NT S +C C G G C P C
Sbjct: 350 CEARLCPEGLYGIKCDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEAC 409
Query: 244 SNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPD------NCVSH-QCQNGGTCQ--DG 294
+CQ + DS C C PGF G DC NC S C+N C DG
Sbjct: 410 QQICSCQNGADCDSVTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDG 469
Query: 295 LDTYTCLCPETWTGWDCSEDVDECETQG-----PPHCRNGGTCQNSAGSFHCVCVSGWGG 349
+C C W G DCS T G C NGG C G+ C C GW G
Sbjct: 470 ----SCTCKAGWHGVDCSIRCPS-GTWGFGCNLTCQCLNGGACNTLDGT--CTCAPGWRG 522
Query: 350 TSCEENLDD-CIAATCAPGSTCIDRVG----SFSCLCPPGRTGLLCHLEDMC-------- 396
CE D CA C G + C C PG +G+ H + +C
Sbjct: 523 EKCELPCQDGTYGLNCAERCDCSHADGCHPTTGHCRCLPGWSGV--HCDSVCAEGRWGPN 580
Query: 397 LSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTP 456
S PC+ S +P G +C C PG+ G TC +
Sbjct: 581 CSLPCYCKNGASCSPDDG--ICECAPGFRGTTCQR------------------------- 613
Query: 457 GSFNCLCPPGYTGSRCEADHNECL--SQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVET 514
+C PG+ G RC +C+ S PCH T C C PG G LC
Sbjct: 614 -----ICSPGFYGHRCSQTCPQCVHSSGPCHH--------ITGLCDCLPGFTGALCNEVC 660
Query: 515 ------NECAS-APCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSP-------C 560
CA C N+ C+ + C C PG+ G+ C + P C
Sbjct: 661 PSGRFGKNCAGICTCTNNGTCNPI--DRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNC 718
Query: 561 ANGGQCQDQPGAFHCKCLPGFEGPRCQTEV-------DECLSDPCPVGASCLDLPGAFFC 613
NG C G CKC PG+ G C D L C GA C + G C
Sbjct: 719 HNGAFCSAYDG--ECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQ--C 774
Query: 614 LCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPE-----DNCTCH 668
C +GF G+ CE QK CP G+ G + +N TC
Sbjct: 775 TCRTGFMGRHCE-----------------QK------CPSGTYGYGCRQICDCLNNSTCD 811
Query: 669 HGHCQRSSCVCDVGWTGPECE 689
H +C C GW G C+
Sbjct: 812 H---ITGTCYCSPGWKGARCD 829
Score = 207 bits (526), Expect = 1e-52
Identities = 194/657 (29%), Positives = 237/657 (36%), Gaps = 117/657 (17%)
Query: 717 CPTGYTG-----PTCSEEMTACHSGPCL--NGGSCNPSPGGYYCT--CPPSHTGPQCQTS 767
CP Y P C+++ C G C+ N C P GG C+ C H GP C
Sbjct: 95 CPGFYESGEMCVPHCADK---CVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHC--- 148
Query: 768 TDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQG 827
T C C NG C P T +C CA GF+G RCE + + C R CQ+
Sbjct: 149 TSRC---QCKNGALC--NPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQNGATC 203
Query: 828 PR----CLCPTGYTGGSCQTLMDLCAQKP-CPRNSHCLQTGPSFH----CLCLQGWTGPL 878
C CP GYTG C+ L P C + C G H C C GW G +
Sbjct: 204 DHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSGWMGTV 263
Query: 879 CNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDH-------V 931
C P C + + CHNGG C + CHC PG+ G CQD V
Sbjct: 264 CGQP---CPEGRFGKNCSQECQCHNGGTC--DAATGQCHCSPGYTGERCQDECPVGTYGV 318
Query: 932 NPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDA-------CQSQ-PCHNHGTC 983
E+ C NG C SG C C G+ G+ C L C + PCH T
Sbjct: 319 LCAETCQCVNGGKCY-HVSG-ACLCEAGFAGERCEARLCPEGLYGIKCDKRCPCHLENTH 376
Query: 984 TPKPGGFHCACPPGFVGLRCE-----GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGH 1038
+ P CAC PG+ GL C G E Q C A C S+ C C PG
Sbjct: 377 SCHPMSGECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGK--CTCAPGF 434
Query: 1039 TGQWCEVEIDPCHSQPC---FHGGTCEATAG-------SPLGFICHCPKGFEGPTCSHRA 1088
G C S PC +G C + G SP+ C C G+ G CS R
Sbjct: 435 KGIDC--------STPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRC 486
Query: 1089 PS--CGFH-----HCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTP----PAPKGCGPP 1137
PS GF C +GG C C C G+ G C P C
Sbjct: 487 PSGTWGFGCNLTCQCLNGGAC-----NTLDGTCTCAPGWRGEKCELPCQDGTYGLNCAER 541
Query: 1138 SPCLYNGSCSETTG-----LGGPGFRCS--CPHSSPGPRCQKP--GAKGCEGRSGDGACD 1188
C + C TTG G G C C GP C P G DG C+
Sbjct: 542 CDCSHADGCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSLPCYCKNGASCSPDDGICE 601
Query: 1189 AGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRC-WLLFRDGQCHPQCDSEECL--FDGYDC 1245
PG + G C + G C + G CH +CL F G C
Sbjct: 602 C---APG--FRGTTCQRICSPGFYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALC 656
Query: 1246 -ETPPACTPAYDQYCH---DHFHNGHCEKGCNTAEC--GWDGGDCRPEDGDPEWGPS 1296
E P + + + C +NG C + +C GW G DC WGP+
Sbjct: 657 NEVCP--SGRFGKNCAGICTCTNNGTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPN 711
Score = 162 bits (409), Expect = 4e-39
Identities = 168/585 (28%), Positives = 209/585 (35%), Gaps = 155/585 (26%)
Query: 762 PQCQTSTDYCVSAPCFNGGTCVNRPG----TFSCLCAMGFQGPRCEGKLRPSCADSPCRN 817
P C D CV C TC PG S C GP C + + C+N
Sbjct: 107 PHC---ADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDHWGPHCTSRCQ-------CKN 156
Query: 818 RATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGP 877
A C +P C C G+ G C+ C QG G
Sbjct: 157 GALC--NPITGACHCAAGFRGWRCEDR-------------------------CEQGTYGN 189
Query: 878 LCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQD------HV 931
C+ CQ C NG C + C CPPG+ G+ C+D H
Sbjct: 190 DCH---QRCQ-------------CQNGATC--DHVTGECRCPPGYTGAFCEDLCPPGKHG 231
Query: 932 NPCESR-PCQNGATC------MAQPSGYL---C--QCAPGYDGQNCSKELDACQSQPCHN 979
CE R PCQNG C + PSG++ C C G G+NCS+E CQ CHN
Sbjct: 232 PQCEQRCPCQNGGVCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQE---CQ---CHN 285
Query: 980 HGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT 1039
GTC G C C PG+ G RC+ DEC P GT + + A CQC+ G
Sbjct: 286 GGTCDAATG--QCHCSPGYTGERCQ---DEC------PVGT---YGVLCAETCQCVNGGK 331
Query: 1040 GQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSC--GFHHCH 1097
C C + F G CEA CP+G G C R P H CH
Sbjct: 332 ---CYHVSGACLCEAGFAGERCEARL---------CPEGLYGIKCDKRCPCHLENTHSCH 379
Query: 1098 HGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAP----KGCGPPSPCLYNGSCSETTGLG 1153
P G CAC G+ G C +P + C C C TG
Sbjct: 380 --------PMSG---ECACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTG-- 426
Query: 1154 GPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGAC----DAGCSGPGGN------WDGGDC 1203
+C+C G C P G G + C DA CS G+ W G DC
Sbjct: 427 ----KCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKNDAVCSPVDGSCTCKAGWHGVDC 482
Query: 1204 SLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECL--FDGYDCETPPACTPA-YDQYCH 1260
S+ P G + C L G C+ + C + G CE P C Y C
Sbjct: 483 SIRCPSGTWGFGCNLTCQCL-NGGACNTLDGTCTCAPGWRGEKCELP--CQDGTYGLNCA 539
Query: 1261 DHFHNGHCEKGCN--TAEC----GWDGGDCRPEDGDPEWGPSLAL 1299
+ H + GC+ T C GW G C + WGP+ +L
Sbjct: 540 ERCDCSHAD-GCHPTTGHCRCLPGWSGVHCDSVCAEGRWGPNCSL 583
Score = 114 bits (285), Expect = 1e-24
Identities = 125/410 (30%), Positives = 151/410 (36%), Gaps = 118/410 (28%)
Query: 918 CPPGF--QGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDA---- 971
C PGF G +C H C + C +G C+A + CQC PG+ G NCS D
Sbjct: 94 CCPGFYESGEMCVPH---CADK-CVHGR-CIAPNT---CQCEPGWGGTNCSSACDGDHWG 145
Query: 972 --CQSQ-PCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAA--CHSL 1026
C S+ C N C P G HCA GF G RCE D C GT CH
Sbjct: 146 PHCTSRCQCKNGALCNPITGACHCAA--GFRGWRCE---DRC------EQGTYGNDCHQR 194
Query: 1027 ANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSH 1086
CQC G T C+ C P + G CE CP G GP C
Sbjct: 195 -----CQCQNGAT---CDHVTGECRCPPGYTGAFCEDL----------CPPGKHGPQCEQ 236
Query: 1087 RAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKG-----CGPPSPCL 1141
R P C +GG+C C+C SG+ G C P P+G C C
Sbjct: 237 RCP------CQNGGVC-----HHVTGECSCPSGWMGTVC-GQPCPEGRFGKNCSQECQCH 284
Query: 1142 YNGSCSETTGL-----GGPGFRC--SCPHSSPG----PRCQKPGAKGCEGRSGDGACDAG 1190
G+C TG G G RC CP + G CQ C SG C+AG
Sbjct: 285 NGGTCDAATGQCHCSPGYTGERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAG 344
Query: 1191 CSG--------PGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDG 1242
+G P G + G C K CP H L CHP S EC
Sbjct: 345 FAGERCEARLCPEGLY-GIKCD-------KRCPCH-----LENTHSCHPM--SGEC---- 385
Query: 1243 YDCETPPACTPAY-----DQYCHDHFHNGHCEKGC---NTAECGWDGGDC 1284
AC P + ++ C F+ C++ C N A+C G C
Sbjct: 386 -------ACKPGWSGLYCNETCSPGFYGEACQQICSCQNGADCDSVTGKC 428
>gi|116235485 delta-notch-like EGF repeat-containing transmembrane
[Homo sapiens]
Length = 737
Score = 248 bits (633), Expect = 4e-65
Identities = 126/311 (40%), Positives = 161/311 (51%), Gaps = 17/311 (5%)
Query: 326 CRNGGTCQN--SAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRV-----GSFS 378
C G C S +F C C + GT CEE D C C ++CID +F+
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFCEE-YDACQRKPCQNNASCIDANEKQDGSNFT 377
Query: 379 CLCPPGRTGLLCHLE-DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECL 437
C+C PG TG LC + D C+ PC A C ++ L+G T C C GY G C + +D C
Sbjct: 378 CVCLPGYTGELCQSKIDYCILDPCRNGATCISS-LSGFT-CQCPEGYFGSACEEKVDPC- 434
Query: 438 MAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATF 497
SPC++ G+C F C C PG+TG C + C PC G TC + ++
Sbjct: 435 ----ASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHG-TCRSVGTSY 489
Query: 498 HCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRS 557
CLC PG G CE E NEC SAPCLN A C DL+NG++C+CL + GT CE D C +
Sbjct: 490 KCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCAN 549
Query: 558 SPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPS 617
C NG C C C PGF G C +++EC S+PC G SCLD P + C CP
Sbjct: 550 VSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPH 609
Query: 618 GFTGQLCEVPL 628
G+ G CE+ L
Sbjct: 610 GWVGANCEIHL 620
Score = 243 bits (621), Expect = 1e-63
Identities = 119/312 (38%), Positives = 161/312 (51%), Gaps = 20/312 (6%)
Query: 700 CAHGGTCYPQPSG--YNCTCPTGYTGPTCSEEMTACHSGPCLNGGSC---NPSPGG--YY 752
C+ G C +PS ++CTC Y G C EE AC PC N SC N G +
Sbjct: 319 CSGKGKCTTKPSEATFSCTCEEQYVGTFC-EEYDACQRKPCQNNASCIDANEKQDGSNFT 377
Query: 753 CTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCAD 812
C C P +TG CQ+ DYC+ PC NG TC++ F+C C G+ G CE K+ P CA
Sbjct: 378 CVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDP-CAS 436
Query: 813 SPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQ 872
SPC+N TC C C G+TG +C L+D CA PC + C G S+ CLC
Sbjct: 437 SPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPCAHGT-CRSVGTSYKCLCDP 495
Query: 873 GWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVN 932
G+ G C + C +S+ C N C D Y C C ++G+ C+ + +
Sbjct: 496 GYHGLYCEEEYNEC----------LSAPCLNAATCRDLVNGYECVCLAEYKGTHCELYKD 545
Query: 933 PCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHC 992
PC + C NGATC + C CAPG+ G+ C +++ C S PCH+ G+C +P G++C
Sbjct: 546 PCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHHGGSCLDQPNGYNC 605
Query: 993 ACPPGFVGLRCE 1004
CP G+VG CE
Sbjct: 606 HCPHGWVGANCE 617
Score = 221 bits (563), Expect = 6e-57
Identities = 116/330 (35%), Positives = 148/330 (44%), Gaps = 22/330 (6%)
Query: 725 TCSEEMTACHSGPCLNGGSCN--PSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTC 782
TC + + C G C PS + CTC + G C+ D C PC N +C
Sbjct: 306 TCVPGESHANDLECSGKGKCTTKPSEATFSCTCEEQYVGTFCE-EYDACQRKPCQNNASC 364
Query: 783 VNRP-----GTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYT 837
++ F+C+C G+ G C+ K+ C PCRN ATC S G C CP GY
Sbjct: 365 IDANEKQDGSNFTCVCLPGYTGELCQSKI-DYCILDPCRNGATCISSLSGFTCQCPEGYF 423
Query: 838 GGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDV 897
G +C+ +D CA PC N C G F C C G+TGP C + C +
Sbjct: 424 GSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCA---------L 474
Query: 898 SSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCA 957
S H G C G SY C C PG+ G C++ N C S PC N ATC +GY C C
Sbjct: 475 SPCAH--GTCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVCL 532
Query: 958 PGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHP 1017
Y G +C D C + C N TC C C PGF G C+ D++EC PCH
Sbjct: 533 AEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCHH 592
Query: 1018 TGTAACHSLANAFYCQCLPGHTGQWCEVEI 1047
G +C N + C C G G CE+ +
Sbjct: 593 GG--SCLDQPNGYNCHCPHGWVGANCEIHL 620
Score = 211 bits (538), Expect = 4e-54
Identities = 108/285 (37%), Positives = 139/285 (48%), Gaps = 17/285 (5%)
Query: 535 FQCICLPGFSGTRCEEDIDECRSSPCANGGQCQD----QPGA-FHCKCLPGFEGPRCQTE 589
F C C + GT CEE D C+ PC N C D Q G+ F C CLPG+ G CQ++
Sbjct: 334 FSCTCEEQYVGTFCEE-YDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSK 392
Query: 590 VDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCE--VPLCAPNLCQPKQICKDQKDKA 647
+D C+ DPC GA+C+ F C CP G+ G CE V CA + CQ C
Sbjct: 393 IDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHF 452
Query: 648 NCLCPDG--SPGCAPPEDNCT---CHHGHCQRSS----CVCDVGWTGPECEAELGGCISA 698
C C G P CA D C C HG C+ C+CD G+ G CE E C+SA
Sbjct: 453 TCNCSPGFTGPTCAQLIDFCALSPCAHGTCRSVGTSYKCLCDPGYHGLYCEEEYNECLSA 512
Query: 699 PCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPS 758
PC + TC +GY C C Y G C C + CLNG +C+ C C P
Sbjct: 513 PCLNAATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPG 572
Query: 759 HTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCE 803
TG +C + C S PC +GG+C+++P ++C C G+ G CE
Sbjct: 573 FTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCE 617
Score = 208 bits (530), Expect = 4e-53
Identities = 113/329 (34%), Positives = 157/329 (47%), Gaps = 32/329 (9%)
Query: 381 CPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQ 440
C PG + H D+ C G +C+T P + C C+ Y G C ++ D C
Sbjct: 307 CVPGES----HANDL----ECSGKGKCTTKPSEATFSCTCEEQYVGTFC-EEYDACQR-- 355
Query: 441 QGPSPCEHGGSCLNTP-----GSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLA 495
PC++ SC++ +F C+C PGYTG C++ + C+ PC G+TC+ L+
Sbjct: 356 ---KPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLS 412
Query: 496 TFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDEC 555
F C CP G G CE + + CAS+PC N+ C+ F C C PGF+G C + ID C
Sbjct: 413 GFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFC 472
Query: 556 RSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLC 615
SPCA+G C+ ++ C C PG+ G C+ E +ECLS PC A+C DL + C+C
Sbjct: 473 ALSPCAHG-TCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDLVNGYECVC 531
Query: 616 PSGFTGQLCEV--PLCAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPEDNCT---CH 668
+ + G CE+ CA C C C+C G G C + C CH
Sbjct: 532 LAEYKGTHCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINECDSNPCH 591
Query: 669 HGHC-----QRSSCVCDVGWTGPECEAEL 692
HG +C C GW G CE L
Sbjct: 592 HGGSCLDQPNGYNCHCPHGWVGANCEIHL 620
Score = 204 bits (520), Expect = 5e-52
Identities = 121/333 (36%), Positives = 154/333 (46%), Gaps = 23/333 (6%)
Query: 182 CPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPR 241
C PG E HA + EC G C S +F C C G CE C +
Sbjct: 307 CVPG-ESHANDL---EC-SGKGKCTTKPS----EATFSCTCEEQYVGTFCE-EYDACQRK 356
Query: 242 GCSNGGTCQLMPEK-DSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTC 300
C N +C EK D + C+C PG+ G C+ D C+ C+NG TC L +TC
Sbjct: 357 PCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSLSGFTC 416
Query: 301 LCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCI 360
CPE + G C E VD C + C+N GTC F C C G+ G +C + +D C
Sbjct: 417 QCPEGYFGSACEEKVDPCASS---PCQNNGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCA 473
Query: 361 AATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DMCLSQPCHGDAQCSTNPLTGSTLCL 419
+ CA G TC S+ CLC PG GL C E + CLS PC A C L C+
Sbjct: 474 LSPCAHG-TCRSVGTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATC--RDLVNGYECV 530
Query: 420 CQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNEC 479
C Y G C D C C +G +C + + C+C PG+TG C+ D NEC
Sbjct: 531 CLAEYKGTHCELYKDPCANVS-----CLNGATCDSDGLNGTCICAPGFTGEECDIDINEC 585
Query: 480 LSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEV 512
S PCH G +CLD ++C CP G G CE+
Sbjct: 586 DSNPCHHGGSCLDQPNGYNCHCPHGWVGANCEI 618
Score = 197 bits (500), Expect = 1e-49
Identities = 97/284 (34%), Positives = 138/284 (48%), Gaps = 28/284 (9%)
Query: 33 EPCANGGTCLSLSLGQG----TCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPL 88
+PC N +C+ + Q TC C PG+ GE CQ C+NG +C + L
Sbjct: 356 KPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISSL---- 411
Query: 89 GLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPG 148
F C C G+ G C+ K+ DPC S C G C++ C+C PG
Sbjct: 412 ----------SGFTCQCPEGYFGSACEEKV-DPCASSPCQNNGTCYVDGV-HFTCNCSPG 459
Query: 149 WTGEQC-QLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPK 207
+TG C QL DFC+ +PC + G C + +C C PG+ G CE + NEC PC
Sbjct: 460 FTGPTCAQLIDFCALSPCAH-GTCRSVGTSYKCLCDPGYHGLYCEEEYNECLS--APCLN 516
Query: 208 GTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPG 267
+C + + ++C+C +G CEL PC C NG TC + D C+C PG
Sbjct: 517 AATCRDLVNGYECVCLAEYKGTHCELYKDPCANVSCLNGATC----DSDGLNGTCICAPG 572
Query: 268 FIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDC 311
F G +C+++ + C S+ C +GG+C D + Y C CP W G +C
Sbjct: 573 FTGEECDIDINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANC 616
Score = 194 bits (493), Expect = 7e-49
Identities = 101/312 (32%), Positives = 140/312 (44%), Gaps = 32/312 (10%)
Query: 865 SFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDS-----GPSYFCHCP 919
+F C C + + G C +CQ+ C N C+D+ G ++ C C
Sbjct: 333 TFSCTCEEQYVGTFCE-EYDACQRKP----------CQNNASCIDANEKQDGSNFTCVCL 381
Query: 920 PGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHN 979
PG+ G LCQ ++ C PC+NGATC++ SG+ CQC GY G C +++D C S PC N
Sbjct: 382 PGYTGELCQSKIDYCILDPCRNGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQN 441
Query: 980 HGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT 1039
+GTC F C C PGF G C +D C PC C S+ ++ C C PG+
Sbjct: 442 NGTCYVDGVHFTCNCSPGFTGPTCAQLIDFCALSPC---AHGTCRSVGTSYKCLCDPGYH 498
Query: 1040 GQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHG 1099
G +CE E + C S PC + TC G+ C C ++G C C C +G
Sbjct: 499 GLYCEEEYNECLSAPCLNAATCRDLVN---GYECVCLAEYKGTHCELYKDPCANVSCLNG 555
Query: 1100 GLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRC 1159
C G C C G+ G +C +PC + GSC + G+ C
Sbjct: 556 ATC---DSDGLNGTCICAPGFTGEEC---DIDINECDSNPCHHGGSCLDQPN----GYNC 605
Query: 1160 SCPHSSPGPRCQ 1171
CPH G C+
Sbjct: 606 HCPHGWVGANCE 617
Score = 188 bits (478), Expect = 4e-47
Identities = 104/338 (30%), Positives = 152/338 (44%), Gaps = 31/338 (9%)
Query: 61 TCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLED 120
TC + N C G C + P +F CTC + G C+ D
Sbjct: 306 TCVPGESHANDLECSGKGKC------------TTKPSEATFSCTCEEQYVGTFCEEY--D 351
Query: 121 PCPPSFCSKRGRCHIQASGRPQ-----CSCMPGWTGEQCQLR-DFCSANPCVNGGVCLAT 174
C C C I A+ + C C+PG+TGE CQ + D+C +PC NG C+++
Sbjct: 352 ACQRKPCQNNASC-IDANEKQDGSNFTCVCLPGYTGELCQSKIDYCILDPCRNGATCISS 410
Query: 175 YPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELR 234
C CP G+ G ACE V+ C PC +C+ F C C G GP C
Sbjct: 411 LSGFTCQCPEGYFGSACEEKVDPCAS--SPCQNNGTCYVDGVHFTCNCSPGFTGPTCAQL 468
Query: 235 AGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDG 294
C C++ GTC+ + T + CLC PG+ G CE + C+S C N TC+D
Sbjct: 469 IDFCALSPCAH-GTCRSV----GTSYKCLCDPGYHGLYCEEEYNECLSAPCLNAATCRDL 523
Query: 295 LDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEE 354
++ Y C+C + G C D C C NG TC + + C+C G+ G C+
Sbjct: 524 VNGYECVCLAEYKGTHCELYKDPCANVS---CLNGATCDSDGLNGTCICAPGFTGEECDI 580
Query: 355 NLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHL 392
++++C + C G +C+D+ ++C CP G G C +
Sbjct: 581 DINECDSNPCHHGGSCLDQPNGYNCHCPHGWVGANCEI 618
Score = 183 bits (464), Expect = 2e-45
Identities = 171/639 (26%), Positives = 226/639 (35%), Gaps = 157/639 (24%)
Query: 733 CHSGPCLNGGSC---------NPSPGG---YYCTCPPSHTGPQCQTSTDYCVSAPCFNGG 780
C + PC NGG C +P+P G Y CTCP +G CQ D C S PC +G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 781 TCVNRPGT---FSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSP----QGPRCLCP 833
+ + + C+C G++GP CE L A + A Q P Q P + P
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCEQALPSLPATGWTESMAPRQLQPVPATQEPDKILP 167
Query: 834 TGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHC------------------------L 869
+ T QK ++ P C
Sbjct: 168 RSQATVTLPTWQPKTGQKVVEMKWDQVEVIPDIACGNASSNSSAGGRLVSFEVPQNTSVK 227
Query: 870 CLQGWTGPLC---NLPLSSCQKAALSQGIDVSSLCHNGGL-----CVDSGPSYF------ 915
Q T L + + Q+ +L G V+ L +GGL + G ++F
Sbjct: 228 IRQDATASLILLWKVTATGFQQCSLIDGRSVTPLQASGGLVLLEEMLALGNNHFIGFVND 287
Query: 916 -----------------CHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPS--GYLCQC 956
C PG + H N E C C +PS + C C
Sbjct: 288 SVTKSIVALRLTLVVKVSTCVPG------ESHANDLE---CSGKGKCTTKPSEATFSCTC 338
Query: 957 APGYDGQNCSKELDACQSQPCHNHGTC---TPKPGG--FHCACPPGFVGLRCEGDVDECL 1011
Y G C +E DACQ +PC N+ +C K G F C C PG+ G C+ +D C+
Sbjct: 339 EEQYVGTFC-EEYDACQRKPCQNNASCIDANEKQDGSNFTCVCLPGYTGELCQSKIDYCI 397
Query: 1012 DQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGF 1071
PC A C S + F CQC G+ G CE ++DPC S PC + GTC + F
Sbjct: 398 LDPCR--NGATCISSLSGFTCQCPEGYFGSACEEKVDPCASSPCQNNGTCYVDG---VHF 452
Query: 1072 ICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAP 1131
C+C GF GPTC+ C C HG G +C C GY G C
Sbjct: 453 TCNCSPGFTGPTCAQLIDFCALSPCAHG----TCRSVGTSYKCLCDPGYHGLYC--EEEY 506
Query: 1132 KGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQ--KPGAKGCEGRSGDGACDA 1189
C +PCL +C + G+ C C G C+ K +G A
Sbjct: 507 NEC-LSAPCLNAATCRDLVN----GYECVCLAEYKGTHCELYKDPCANVSCLNG-----A 556
Query: 1190 GCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECLFDGYDCETPP 1249
C G N G C C P EEC D +C++ P
Sbjct: 557 TCDSDGLN---GTCI------------------------CAPGFTGEECDIDINECDSNP 589
Query: 1250 ACTPAYDQYCHDHFHNGHCEKGCNTAEC----GWDGGDC 1284
CH H G C N C GW G +C
Sbjct: 590 ---------CH---HGGSCLDQPNGYNCHCPHGWVGANC 616
Score = 111 bits (278), Expect = 6e-24
Identities = 69/202 (34%), Positives = 92/202 (45%), Gaps = 23/202 (11%)
Query: 34 PCANGGTCLSLSLGQGTCQCAPGFLGETC-QFPDPCQNAQLCQNGGSCQALLPAPLGLPS 92
PC N GTC + TC C+PGF G TC Q D C AL P G
Sbjct: 438 PCQNNGTCYVDGV-HFTCNCSPGFTGPTCAQLIDFC-------------ALSPCAHGTCR 483
Query: 93 SPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGE 152
S + S+ C C PG+ G C+ + + C + C C +G +C C+ + G
Sbjct: 484 S---VGTSYKCLCDPGYHGLYCEEEYNE-CLSAPCLNAATCRDLVNGY-ECVCLAEYKGT 538
Query: 153 QCQL-RDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSC 211
C+L +D C+ C+NG C + C C PGF G C+ D+NEC D PC G SC
Sbjct: 539 HCELYKDPCANVSCLNGATCDSDGLNGTCICAPGFTGEECDIDINEC--DSNPCHHGGSC 596
Query: 212 HNTLGSFQCLCPVGQEGPRCEL 233
+ + C CP G G CE+
Sbjct: 597 LDQPNGYNCHCPHGWVGANCEI 618
Score = 68.6 bits (166), Expect = 6e-11
Identities = 32/88 (36%), Positives = 40/88 (45%), Gaps = 17/88 (19%)
Query: 933 PCESRPCQNGATCMAQPS------------GYLCQCAPGYDGQNCSKELDACQSQPCHNH 980
PC ++PC+NG C ++P GY C C G G NC D C S PCH H
Sbjct: 47 PCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCH-H 105
Query: 981 GTCTPKPG----GFHCACPPGFVGLRCE 1004
G C+ G+ C C G+ G CE
Sbjct: 106 GNCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 66.2 bits (160), Expect = 3e-10
Identities = 31/88 (35%), Positives = 40/88 (45%), Gaps = 15/88 (17%)
Query: 693 GGCISAPCAHGGTCYPQPS------------GYNCTCPTGYTGPTCSEEMTACHSGPCLN 740
G C + PC +GG C +P GY+CTCP G +G C C S PC +
Sbjct: 46 GPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHH 105
Query: 741 G---GSCNPSPGGYYCTCPPSHTGPQCQ 765
G S + S GY C C + GP C+
Sbjct: 106 GNCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 65.5 bits (158), Expect = 5e-10
Identities = 33/87 (37%), Positives = 38/87 (43%), Gaps = 11/87 (12%)
Query: 1049 PCHSQPCFHGGTCE----------ATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHH 1098
PC +QPC +GG C A AG P G+ C CP G G C A C + CHH
Sbjct: 47 PCAAQPCRNGGVCTSRPEPDPQHPAPAGEP-GYSCTCPAGISGANCQLVADPCASNPCHH 105
Query: 1099 GGLCLPSPKPGFPPRCACLSGYGGPDC 1125
G S C C GY GP+C
Sbjct: 106 GNCSSSSSSSSDGYLCICNEGYEGPNC 132
Score = 63.2 bits (152), Expect = 3e-09
Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 23/131 (17%)
Query: 203 GPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTF--- 259
G P+G+S N + + P GPC + C NGG C PE D
Sbjct: 25 GAGPRGSSLANPVPAAPLSAP------------GPCAAQPCRNGGVCTSRPEPDPQHPAP 72
Query: 260 -----HLCLCPPGFIGPDCEVNPDNCVSHQCQNG---GTCQDGLDTYTCLCPETWTGWDC 311
+ C CP G G +C++ D C S+ C +G + D Y C+C E + G +C
Sbjct: 73 AGEPGYSCTCPAGISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNC 132
Query: 312 SEDVDECETQG 322
+ + G
Sbjct: 133 EQALPSLPATG 143
Score = 61.6 bits (148), Expect = 7e-09
Identities = 36/116 (31%), Positives = 46/116 (39%), Gaps = 31/116 (26%)
Query: 160 CSANPCVNGGVCLA-TYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSF 218
C+A PC NGGVC + P Q P G G++C
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSC--------------------------- 80
Query: 219 QCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCE 274
CP G G C+L A PC C + G C S +LC+C G+ GP+CE
Sbjct: 81 --TCPAGISGANCQLVADPCASNPCHH-GNCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 60.1 bits (144), Expect = 2e-08
Identities = 32/89 (35%), Positives = 39/89 (43%), Gaps = 14/89 (15%)
Query: 359 CIAATCAPGSTCIDRVG------------SFSCLCPPGRTGLLCHL-EDMCLSQPCH-GD 404
C A C G C R +SC CP G +G C L D C S PCH G+
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 405 AQCSTNPLTGSTLCLCQPGYSGPTCHQDL 433
S++ + LC+C GY GP C Q L
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCEQAL 136
Score = 59.7 bits (143), Expect = 3e-08
Identities = 38/108 (35%), Positives = 49/108 (45%), Gaps = 20/108 (18%)
Query: 17 CVSVVRPRGLLCGSFPEPCAN-----GGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNA 71
CV + +G C + +PCAN G TC S L GTC CAPGF GE C ++
Sbjct: 529 CVCLAEYKGTHCELYKDPCANVSCLNGATCDSDGLN-GTCICAPGFTGEECDIDINECDS 587
Query: 72 QLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE 119
C +GGSC L P G + C C G+ G C+ L+
Sbjct: 588 NPCHHGGSC---LDQPNG-----------YNCHCPHGWVGANCEIHLQ 621
Score = 55.8 bits (133), Expect = 4e-07
Identities = 35/113 (30%), Positives = 46/113 (40%), Gaps = 29/113 (25%)
Query: 745 NPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGT------------FSCL 792
NP P P S GP C + PC NGG C +RP +SC
Sbjct: 35 NPVPAA-----PLSAPGP--------CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCT 81
Query: 793 CAMGFQGPRCEGKLRPSCADSPCRN---RATCQDSPQGPRCLCPTGYTGGSCQ 842
C G G C+ P CA +PC + ++ S G C+C GY G +C+
Sbjct: 82 CPAGISGANCQLVADP-CASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 55.8 bits (133), Expect = 4e-07
Identities = 28/89 (31%), Positives = 36/89 (40%), Gaps = 15/89 (16%)
Query: 555 CRSSPCANGGQCQDQPG------------AFHCKCLPGFEGPRCQTEVDECLSDPCPVG- 601
C + PC NGG C +P + C C G G CQ D C S+PC G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 602 --ASCLDLPGAFFCLCPSGFTGQLCEVPL 628
+S + C+C G+ G CE L
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCEQAL 136
Score = 55.1 bits (131), Expect = 7e-07
Identities = 32/119 (26%), Positives = 49/119 (41%), Gaps = 18/119 (15%)
Query: 411 PLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGP---SPCEHGGSCLNTPG---------- 457
P L L G G + + ++ GP PC +GG C + P
Sbjct: 15 PALALLLLLLGAGPRGSSLANPVPAAPLSAPGPCAAQPCRNGGVCTSRPEPDPQHPAPAG 74
Query: 458 --SFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLAT---FHCLCPPGLEGQLCE 511
++C CP G +G+ C+ + C S PCH G+ ++ + C+C G EG CE
Sbjct: 75 EPGYSCTCPAGISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 55.1 bits (131), Expect = 7e-07
Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 17/88 (19%)
Query: 479 CLSQPCHPGSTCLDLLAT------------FHCLCPPGLEGQLCEVETNECASAPCLNHA 526
C +QPC G C + C CP G+ G C++ + CAS PC +H
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPC-HHG 106
Query: 527 DC----HDLLNGFQCICLPGFSGTRCEE 550
+C +G+ CIC G+ G CE+
Sbjct: 107 NCSSSSSSSSDGYLCICNEGYEGPNCEQ 134
Score = 51.6 bits (122), Expect = 8e-06
Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 12/92 (13%)
Query: 277 PDNCVSHQCQNGGTCQD------------GLDTYTCLCPETWTGWDCSEDVDECETQGPP 324
P C + C+NGG C G Y+C CP +G +C D C +
Sbjct: 45 PGPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCH 104
Query: 325 HCRNGGTCQNSAGSFHCVCVSGWGGTSCEENL 356
H + +S+ + C+C G+ G +CE+ L
Sbjct: 105 HGNCSSSSSSSSDGYLCICNEGYEGPNCEQAL 136
Score = 50.8 bits (120), Expect = 1e-05
Identities = 26/86 (30%), Positives = 34/86 (39%), Gaps = 15/86 (17%)
Query: 517 CASAPCLNHADCHDLLN------------GFQCICLPGFSGTRCEEDIDECRSSPCANG- 563
CA+ PC N C G+ C C G SG C+ D C S+PC +G
Sbjct: 48 CAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNPCHHGN 107
Query: 564 --GQCQDQPGAFHCKCLPGFEGPRCQ 587
+ C C G+EGP C+
Sbjct: 108 CSSSSSSSSDGYLCICNEGYEGPNCE 133
Score = 49.7 bits (117), Expect = 3e-05
Identities = 22/58 (37%), Positives = 26/58 (44%), Gaps = 3/58 (5%)
Query: 676 SCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPS---GYNCTCPTGYTGPTCSEEM 730
SC C G +G C+ C S PC HG S GY C C GY GP C + +
Sbjct: 79 SCTCPAGISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCEQAL 136
Score = 49.3 bits (116), Expect = 4e-05
Identities = 30/101 (29%), Positives = 43/101 (42%), Gaps = 14/101 (13%)
Query: 1082 PTCSHRAPS-CGFHHCHHGGLCL--PSPKPGFPP-------RCACLSGYGGPDCLTPPAP 1131
P AP C C +GG+C P P P P C C +G G +C P
Sbjct: 38 PAAPLSAPGPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGYSCTCPAGISGANCQLVADP 97
Query: 1132 KGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQK 1172
C +PC ++G+CS ++ G+ C C GP C++
Sbjct: 98 --CAS-NPC-HHGNCSSSSSSSSDGYLCICNEGYEGPNCEQ 134
Score = 45.8 bits (107), Expect = 4e-04
Identities = 43/142 (30%), Positives = 54/142 (38%), Gaps = 37/142 (26%)
Query: 2 QPPSLLLLLLLLLLLCVSVVRPRGL-LCGSFP------------EPCANGGTCLS----- 43
Q P LL L LLL + PRG L P +PC NGG C S
Sbjct: 7 QAPGAQLLPALALLLLLLGAGPRGSSLANPVPAAPLSAPGPCAAQPCRNGGVCTSRPEPD 66
Query: 44 ----LSLGQG--TCQCAPGFLGETCQF-PDPCQNAQLCQNGGSCQALLPAPLGLPSSPSP 96
G+ +C C G G CQ DPC + C +G +C SS S
Sbjct: 67 PQHPAPAGEPGYSCTCPAGISGANCQLVADPCASNP-CHHG-NCS----------SSSSS 114
Query: 97 LTPSFLCTCLPGFTGERCQAKL 118
+ +LC C G+ G C+ L
Sbjct: 115 SSDGYLCICNEGYEGPNCEQAL 136
Score = 45.1 bits (105), Expect = 7e-04
Identities = 33/111 (29%), Positives = 48/111 (43%), Gaps = 14/111 (12%)
Query: 88 LGLPSSPSPLTPSFLCTCLPGFTGERCQAKLE-DPCPPSFCSKRGRCHIQASGRPQCSCM 146
L P +PL+ C P G C ++ E DP P+ + G C+C
Sbjct: 33 LANPVPAAPLSAPGPCAAQPCRNGGVCTSRPEPDPQHPAPAGEPGY---------SCTCP 83
Query: 147 PGWTGEQCQL-RDFCSANPCVNGGVCLATYPQIQ---CHCPPGFEGHACER 193
G +G CQL D C++NPC +G ++ C C G+EG CE+
Sbjct: 84 AGISGANCQLVADPCASNPCHHGNCSSSSSSSSDGYLCICNEGYEGPNCEQ 134
>gi|4557733 latent transforming growth factor beta binding protein 2
[Homo sapiens]
Length = 1821
Score = 247 bits (630), Expect = 9e-65
Identities = 291/1068 (27%), Positives = 394/1068 (36%), Gaps = 252/1068 (23%)
Query: 95 SPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGW----T 150
+P T + PG +RC A + C P C + +C C PG+ +
Sbjct: 831 TPSTDVLVTLSTPGI--DRCAAGATNVCGPGTC-------VNLPDGYRCVCSPGYQLHPS 881
Query: 151 GEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGF----EGHACE-RDVNECFQDPGPC 205
C + C +PC G C+ C C PG+ G E +D+NEC + PG C
Sbjct: 882 QAYCTDDNECLRDPCKGKGRCINRVGSYSCFCYPGYTLATSGATQECQDINEC-EQPGVC 940
Query: 206 PKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPP-RGCSNGGTCQLMPEKDSTFHLCLC 264
G C NT GS+ C C G +R G C C + GTC
Sbjct: 941 -SGGQCTNTEGSYHCECDQGY----IMVRKGHCQDINECRHPGTC--------------- 980
Query: 265 PPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCL-CPETWTGWDCS-EDVDECETQG 322
PD G C + +YTCL C E + G S DV+EC T G
Sbjct: 981 ------PD----------------GRCVNSPGSYTCLACEEGYRGQSGSCVDVNECLTPG 1018
Query: 323 PPHCRNGGTCQNSAGSFHCVCVSGWGGTSCE---ENLDDCIAATCAPGSTCIDRVGSFSC 379
C + G C N GSF C C G+ TS E +++D+C + P C++ GSF+C
Sbjct: 1019 V--CAH-GKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFAC 1075
Query: 380 -LCPPG----RTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCL-CQPGYS----GPTC 429
C G G C D C C+ GS C C GY G +C
Sbjct: 1076 SACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNT--AGSFSCKDCDGGYRPSPLGDSC 1133
Query: 430 HQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY---TGSRCEADHNECLSQP-CH 485
+D+DEC + P GG C NT GS+ CLCP G+ G+ CE D NEC+ + C
Sbjct: 1134 -EDVDEC----EDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCE-DVNECMGEEHCA 1187
Query: 486 PGSTCLDLLATFHCLCPPGL---EGQLCEVETNECASA-PCLNHADCHDLLNGFQCICLP 541
P CL+ +F CLC PG EG + +ECA+ PC+ C + F C+C
Sbjct: 1188 PHGECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCVG-GHCVNTEGSFNCLCET 1246
Query: 542 GFSGT----RCEEDIDECR--SSPCANGGQCQDQPGAFHC--KCLPGFE-GPRCQ-TEVD 591
GF + C DIDEC P +C++ PG++ C C PGF P ++D
Sbjct: 1247 GFQPSPESGEC-VDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDID 1305
Query: 592 ECLSDP-CPVGASCLDLPGAFFCLCPSGFT----------------------GQLCE--- 625
EC +D C C + G+F CLC GF LCE
Sbjct: 1306 ECANDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVCGAALCENVE 1365
Query: 626 ---VPLCAPNL---------CQPKQICKDQKDKANCLCPDGSPGCAPPEDNC-TCHHGHC 672
+ LCA +L C+P+ +A P G AP +C + GH
Sbjct: 1366 GSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEA----PTGDHAPAPTRMDCYSGQKGHA 1421
Query: 673 QRSS----------CVCDVG--WTGPECEAELGGCISAPCAHGGTCYPQPSGY---NCTC 717
SS C C G W G C+ C S A P GY
Sbjct: 1422 PCSSVLGRNTTQAECCCTQGASW-GDACDL----CPSEDSAEFSEICPSGKGYIPVEGAW 1476
Query: 718 PTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSH----TGPQCQTSTDYCVS 773
G T T ++E G C NG N P GY C C P + +C+ D C
Sbjct: 1477 TFGQTMYTDADECVIFGPGLCPNGRCLNTVP-GYVCLCNPGFHYDASHKKCE-DHDECQD 1534
Query: 774 APCFNGGTCVNRPGTFSCLCA----MGFQGPRCEGKLRPSCADSP--------CRNRAT- 820
C N G CVN G+F C C+ + RC S D P C + T
Sbjct: 1535 LACEN-GECVNTEGSFHCFCSPPLTLDLSQQRCMNS-TSSTEDLPDHDIHMDICWKKVTN 1592
Query: 821 --CQDSPQGPR-----CLCPTGYTGG---------SCQTLMDLC------AQK------- 851
C + +G R C C G S + LC A++
Sbjct: 1593 DVCSEPLRGHRTTYTECCCQDGEAWSQQCALCPPRSSEVYAQLCNVARIEAEREAGVHFR 1652
Query: 852 ------PCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGG 905
P P + H GP + GP +P + A D + + +
Sbjct: 1653 PGYEYGPGPDDLHYSIYGPD--GAPFYNYLGPEDTVPEPAFPNTA-GHSADRTPILESPL 1709
Query: 906 LCVDSGPSYFC---HCPPGFQGSLCQD--HVNPCESRPCQNGATCMAQPSGYLCQCAPGY 960
+ P Y P GF+G ++ +N CE+ C+ GY C C G+
Sbjct: 1710 QPSELQPHYVASHPEPPAGFEGLQAEECGILNGCEN------GRCVRVREGYTCDCFEGF 1763
Query: 961 DGQNCSKELDACQSQPCHN---------HGTCTPKPGGFHCACPPGFV 999
Q + + C + HG C G + C C PG+V
Sbjct: 1764 --QLDAAHMACVDVNECDDLNGPAVLCVHGYCENTEGSYRCHCSPGYV 1809
Score = 222 bits (566), Expect = 2e-57
Identities = 230/803 (28%), Positives = 304/803 (37%), Gaps = 153/803 (19%)
Query: 356 LDDCIAAT---CAPGSTCIDRVGSFSCLCPPGR----TGLLCHLEDMCLSQPCHGDAQCS 408
+D C A C PG TC++ + C+C PG + C ++ CL PC G +C
Sbjct: 845 IDRCAAGATNVCGPG-TCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCI 903
Query: 409 TNPLTGSTLCLCQPGY----SGPTCH-QDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLC 463
GS C C PGY SG T QD++EC + P C GG C NT GS++C C
Sbjct: 904 NR--VGSYSCFCYPGYTLATSGATQECQDINEC----EQPGVCS-GGQCTNTEGSYHCEC 956
Query: 464 PPGYTGSR---CEADHNECLSQPCHPGSTCLDLLATFHCL-CPPGLEGQLCE-VETNECA 518
GY R C+ D NEC P C++ ++ CL C G GQ V+ NEC
Sbjct: 957 DQGYIMVRKGHCQ-DINECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNECL 1015
Query: 519 SAPCLNHADCHDLLNGFQCICLPGFSGTRCE---EDIDECRSSPCANGGQCQDQPGAFHC 575
+ H C +L F+C C G+ T E +D+DEC S G C + G+F C
Sbjct: 1016 TPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFAC 1075
Query: 576 K-CLPGF----EGPRCQTEVDEC-LSDPCPVGASCLDLPGAFFCL-CPSGFT----GQLC 624
C G+ +G C+ ++DEC CP G C + G+F C C G+ G C
Sbjct: 1076 SACENGYWVNEDGTACE-DLDECAFPGVCPSGV-CTNTAGSFSCKDCDGGYRPSPLGDSC 1133
Query: 625 E-VPLCA-PNLCQPKQICKDQKDKANCLCPDG----------SPGCAPPEDNCTCHHGHC 672
E V C P CK+ CLCP G E++C HG C
Sbjct: 1134 EDVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCA-PHGEC 1192
Query: 673 QRSS----CVCDVGWT----GPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYT-G 723
S C+C G+ G C+ ++ C + GG C +NC C TG+
Sbjct: 1193 LNSHGSFFCLCAPGFVSAEGGTSCQ-DVDECATTDPCVGGHCVNTEGSFNCLCETGFQPS 1251
Query: 724 PTCSE--EMTAC--HSGPCLNGGSCNPSPGGYYCT--CPPS-HTGPQ--CQTSTDYCVSA 774
P E ++ C + P C SPG Y C C P H P C +
Sbjct: 1252 PESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECANDT 1311
Query: 775 PCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPS---CAD-SPCR------NRATCQDS 824
C + G C N G+F CLC GF+ + PS C D + C A C++
Sbjct: 1312 MCGSHGFCDNTDGSFRCLCDQGFE-------ISPSGWDCVDVNECELMLAVCGAALCENV 1364
Query: 825 PQGPRCLC---------------PTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFH-- 867
CLC P G GG + P P C +G H
Sbjct: 1365 EGSFLCLCASDLEEYDAQEGHCRPRG-AGGQSMSEAPTGDHAPAPTRMDCY-SGQKGHAP 1422
Query: 868 -------------CLCLQGWT-GPLCNLPLSSCQKAALSQGIDVSSLCHNG-GLCVDSGP 912
C C QG + G C+L S + S +C +G G G
Sbjct: 1423 CSSVLGRNTTQAECCCTQGASWGDACDLCPSE-------DSAEFSEICPSGKGYIPVEGA 1475
Query: 913 SYFCHCPPGFQGSLCQDHVNPCE---SRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKEL 969
F G + C C NG C+ GY+C C PG+ K+
Sbjct: 1476 WTF--------GQTMYTDADECVIFGPGLCPNGR-CLNTVPGYVCLCNPGFHYDASHKKC 1526
Query: 970 ---DACQSQPCHNHGTCTPKPGGFHCAC-PPGFVGL---RCEGDVDECLDQPCHPTGTAA 1022
D CQ C N G C G FHC C PP + L RC D P H
Sbjct: 1527 EDHDECQDLACEN-GECVNTEGSFHCFCSPPLTLDLSQQRCMNSTSSTEDLPDHDIHMDI 1585
Query: 1023 C-HSLANAFYCQCLPGHTGQWCE 1044
C + N + L GH + E
Sbjct: 1586 CWKKVTNDVCSEPLRGHRTTYTE 1608
Score = 208 bits (530), Expect = 4e-53
Identities = 272/992 (27%), Positives = 363/992 (36%), Gaps = 227/992 (22%)
Query: 33 EPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPS 92
+PC G C++ +G +C C PG+ T CQ+ C+ G C
Sbjct: 894 DPCKGKGRCIN-RVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSG---------G 943
Query: 93 SPSPLTPSFLCTCLPGFTGER---CQAKLEDPCPPSFCSKRGRCHIQASGRPQC-SCMPG 148
+ S+ C C G+ R CQ + + P C GRC + + G C +C G
Sbjct: 944 QCTNTEGSYHCECDQGYIMVRKGHCQ-DINECRHPGTCPD-GRC-VNSPGSYTCLACEEG 1000
Query: 149 WTGEQCQLRDFCSANPCVNGGV-----CLATYPQIQCHCPPGFEGHACER---DVNECFQ 200
+ G+ D N C+ GV C +C C G+E + E+ DV+EC
Sbjct: 1001 YRGQSGSCVD---VNECLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDEC-A 1056
Query: 201 DPGPCPKGTSCHNTLGSFQC-LCP----VGQEGPRCE-----LRAGPCPPRGCSNGGTCQ 250
CP G C NT GSF C C V ++G CE G CP C+N
Sbjct: 1057 SRASCPTGL-CLNTEGSFACSACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSF 1115
Query: 251 LMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQ-NGGTCQDGLDTYTCLCPETW--- 306
+ D + P +G CE + D C Q GG C++ + +Y CLCP+ +
Sbjct: 1116 SCKDCDGGYR-----PSPLGDSCE-DVDECEDPQSSCLGGECKNTVGSYQCLCPQGFQLA 1169
Query: 307 TGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGW----GGTSCEENLDDCIAA 362
G C EDV+EC G HC G C NS GSF C+C G+ GGTSC++ +D+C
Sbjct: 1170 NGTVC-EDVNEC--MGEEHCAPHGECLNSHGSFFCLCAPGFVSAEGGTSCQD-VDECATT 1225
Query: 363 TCAPGSTCIDRVGSFSCLC----PPGRTGLLCHLEDMC--LSQPCHGDAQCSTNPLTGST 416
G C++ GSF+CLC P C D C P G +C +P GS
Sbjct: 1226 DPCVGGHCVNTEGSFNCLCETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSP--GSY 1283
Query: 417 LCL--CQPGY---SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY---- 467
C+ CQPG+ C D+DEC + C G C NT GSF CLC G+
Sbjct: 1284 RCVLGCQPGFHMAPNGDC-IDIDEC----ANDTMCGSHGFCDNTDGSFRCLCDQGFEISP 1338
Query: 468 TGSRCEADHNEC-LSQPCHPGSTCLDLLATFHCLC---------------PPGLEGQ-LC 510
+G C D NEC L + C ++ +F CLC P G GQ +
Sbjct: 1339 SGWDC-VDVNECELMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMS 1397
Query: 511 EVETNECASAP----CLN----HADCHDLL----NGFQCICLPGFS-GTRCE-------- 549
E T + A AP C + HA C +L +C C G S G C+
Sbjct: 1398 EAPTGDHAPAPTRMDCYSGQKGHAPCSSVLGRNTTQAECCCTQGASWGDACDLCPSEDSA 1457
Query: 550 --------------------------EDIDEC---RSSPCANGGQCQDQPGAFHCKCLPG 580
D DEC C N G+C + + C C PG
Sbjct: 1458 EFSEICPSGKGYIPVEGAWTFGQTMYTDADECVIFGPGLCPN-GRCLNTVPGYVCLCNPG 1516
Query: 581 F----EGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFT----GQLCEVPLCAPN 632
F +C+ + DEC C G C++ G+F C C T Q C +
Sbjct: 1517 FHYDASHKKCE-DHDECQDLACENG-ECVNTEGSFHCFCSPPLTLDLSQQRCMNSTSSTE 1574
Query: 633 LCQPKQICKD--QKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSC------------- 677
I D K N +C + G C C G C
Sbjct: 1575 DLPDHDIHMDICWKKVTNDVCSEPLRGHRTTYTECCCQDGEAWSQQCALCPPRSSEVYAQ 1634
Query: 678 VCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTG-----YTGP--TCSEEM 730
+C+V E E E G +G P Y+ P G Y GP T E
Sbjct: 1635 LCNVARI--EAEREAGVHFRPGYEYGPG--PDDLHYSIYGPDGAPFYNYLGPEDTVPEPA 1690
Query: 731 ---TACHSG---PCLNGGSCNPS--PGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTC 782
TA HS P L PS Y + P G + + + + C N G C
Sbjct: 1691 FPNTAGHSADRTPILE-SPLQPSELQPHYVASHPEPPAGFEGLQAEECGILNGCEN-GRC 1748
Query: 783 VNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQ 842
V ++C C GFQ A C + C D GP LC GY
Sbjct: 1749 VRVREGYTCDCFEGFQ---------LDAAHMACVDVNECDDL-NGPAVLCVHGY------ 1792
Query: 843 TLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGW 874
C T S+ C C G+
Sbjct: 1793 ----------------CENTEGSYRCHCSPGY 1808
Score = 199 bits (507), Expect = 2e-50
Identities = 266/1039 (25%), Positives = 362/1039 (34%), Gaps = 232/1039 (22%)
Query: 179 QCHCPPGFEGHACE--RDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAG 236
Q CP G++ +D+NEC G C K C NT GS+ C C G L
Sbjct: 605 QLECPQGYKRLNLTHCQDINECLT-LGLC-KDAECVNTRGSYLCTCRPG-------LMLD 655
Query: 237 PCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLD 296
P R S+ L LC G P C Q +
Sbjct: 656 PSRSRCVSDKAISMLQG-------LCYRSLG---------PGTCTLPLAQR-------IT 692
Query: 297 TYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENL 356
C C W ECE C GT +F +C +G G T ++
Sbjct: 693 KQICCCSRVGKAWG-----SECEK-----CPLPGT-----EAFREICPAGHGYTYASSDI 737
Query: 357 DDCIAAT-----CAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQ---PCHGDAQCS 408
+ P R S L P L + D L P GD+Q
Sbjct: 738 RLSMRKAEEEELARPPREQGQR--SSGALPGPAERQPLRVVTDTWLEAGTIPDKGDSQAG 795
Query: 409 --TNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPG 466
T +T + + + P Q + E + ++ +P L+TPG
Sbjct: 796 QVTTSVTHAPAWVTGNATTPPMPEQGIAE--IQEEQVTPSTDVLVTLSTPGI-------- 845
Query: 467 YTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLE---GQLCEVETNECASAPCL 523
RC A + C PG TC++L + C+C PG + Q + NEC PC
Sbjct: 846 ---DRCAAG----ATNVCGPG-TCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCK 897
Query: 524 NHADCHDLLNGFQCICLPGF----SGTRCE-EDIDECRSSPCANGGQCQDQPGAFHCKCL 578
C + + + C C PG+ SG E +DI+EC +GGQC + G++HC+C
Sbjct: 898 GKGRCINRVGSYSCFCYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECD 957
Query: 579 PGFEGPR---CQTEVDECL-SDPCPVGASCLDLPGAFFCL-CPSGFTGQL--------CE 625
G+ R CQ +++EC CP G C++ PG++ CL C G+ GQ C
Sbjct: 958 QGYIMVRKGHCQ-DINECRHPGTCPDG-RCVNSPGSYTCLACEEGYRGQSGSCVDVNECL 1015
Query: 626 VP-LCAPNLC------------QPKQICKDQK---------DKANC---LC--PDGSPGC 658
P +CA C Q ++ D+K +A+C LC +GS C
Sbjct: 1016 TPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVDECASRASCPTGLCLNTEGSFAC 1075
Query: 659 APPE---------------DNC----TCHHGHCQRS----SCV-CDVGWTG--------- 685
+ E D C C G C + SC CD G+
Sbjct: 1076 SACENGYWVNEDGTACEDLDECAFPGVCPSGVCTNTAGSFSCKDCDGGYRPSPLGDSCED 1135
Query: 686 -PECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGY---TGPTCSEEMTACHSGPCLNG 741
ECE C+ GG C Y C CP G+ G C + C
Sbjct: 1136 VDECEDPQSSCL------GGECKNTVGSYQCLCPQGFQLANGTVCEDVNECMGEEHCAPH 1189
Query: 742 GSCNPSPGGYYCTCPP----SHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGF 797
G C S G ++C C P + G CQ + + PC GG CVN G+F+CLC GF
Sbjct: 1190 GECLNSHGSFFCLCAPGFVSAEGGTSCQDVDECATTDPCV-GGHCVNTEGSFNCLCETGF 1248
Query: 798 QGPRCEGKL--RPSCAD--SPCRNRATCQDSPQGPRCL--CPTGY---TGGSCQTLMDLC 848
Q G+ C D P C++SP RC+ C G+ G C + +
Sbjct: 1249 QPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDCIDIDECA 1308
Query: 849 AQKPCPRNSHCLQTGPSFHCLCLQGW-TGPL---------CNLPLSSCQKAALSQGIDVS 898
C + C T SF CLC QG+ P C L L+ C AAL + ++ S
Sbjct: 1309 NDTMCGSHGFCDNTDGSFRCLCDQGFEISPSGWDCVDVNECELMLAVC-GAALCENVEGS 1367
Query: 899 SLCHNGGLCVDSGPSYFC---HCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYL-- 953
LC LC Y HC P G + P C + G+
Sbjct: 1368 FLC----LCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTRMDCYSGQKGHAPC 1423
Query: 954 ------------CQCAPGYD-GQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVG 1000
C C G G C D C S+ P G+ G
Sbjct: 1424 SSVLGRNTTQAECCCTQGASWGDAC----DLCPSEDSAEFSEICPSGKGYIPVEGAWTFG 1479
Query: 1001 LRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGH----TGQWCEVEIDPCHSQPCF 1056
D DEC+ C + + C C PG + + CE + D C C
Sbjct: 1480 QTMYTDADECVIFGPGLCPNGRCLNTVPGYVCLCNPGFHYDASHKKCE-DHDECQDLAC- 1537
Query: 1057 HGGTCEATAGSPLGFICHC 1075
G C T GS F C C
Sbjct: 1538 ENGECVNTEGS---FHCFC 1553
Score = 154 bits (388), Expect = 1e-36
Identities = 225/828 (27%), Positives = 293/828 (35%), Gaps = 164/828 (19%)
Query: 520 APCLNHADCHDLLNGFQCICLPGFSG---TRCEEDIDECRSSPCANGGQCQDQPGAFHCK 576
APC + NG Q C G+ T C+ DI+EC + +C + G++ C
Sbjct: 590 APCPPRPASPVIENG-QLECPQGYKRLNLTHCQ-DINECLTLGLCKDAECVNTRGSYLCT 647
Query: 577 CLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLC---APNL 633
C PG C+SD + L G LC C +PL +
Sbjct: 648 CRPGL---MLDPSRSRCVSDK-----AISMLQG----LCYRSLGPGTCTLPLAQRITKQI 695
Query: 634 CQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELG 693
C ++ K + CP PG + C HG+ SS D+ + + E E
Sbjct: 696 CCCSRVGKAWGSECE-KCP--LPGTEAFREICPAGHGYTYASS---DIRLSMRKAEEEE- 748
Query: 694 GCISAPCAHGGT----CYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGG---SCNP 746
++ P G P P+ P T E T G G S
Sbjct: 749 --LARPPREQGQRSSGALPGPAERQ---PLRVVTDTWLEAGTIPDKGDSQAGQVTTSVTH 803
Query: 747 SPG---GYYCTCPPSHTG------PQCQTSTDYCV--SAP----CFNG-------GTCVN 784
+P G T P G Q STD V S P C G GTCVN
Sbjct: 804 APAWVTGNATTPPMPEQGIAEIQEEQVTPSTDVLVTLSTPGIDRCAAGATNVCGPGTCVN 863
Query: 785 RPGTFSCLCAMGFQGPRCEGKLRPS---------CADSPCRNRATCQDSPQGPRCLCPTG 835
P + C+C+ G+Q L PS C PC+ + C + C C G
Sbjct: 864 LPDGYRCVCSPGYQ-------LHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCFCYPG 916
Query: 836 YT---GGSCQTLMDL--CAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAA 890
YT G+ Q D+ C Q C T S+HC C QG+ + CQ
Sbjct: 917 YTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYHCECDQGYI----MVRKGHCQ--- 969
Query: 891 LSQGIDVSSLCHNG----GLCVDSGPSYFC-HCPPGFQGSL--CQDHVNPCESRPCQNGA 943
D++ H G G CV+S SY C C G++G C D VN C +
Sbjct: 970 -----DINECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVD-VNECLTPGVCAHG 1023
Query: 944 TCMAQPSGYLCQCAPGY----DGQNCSKELDACQSQPCHNHGTCTPKPGGFHC-ACPPGF 998
C + C C GY D + C +++D C S+ G C G F C AC G+
Sbjct: 1024 KCTNLEGSFRCSCEQGYEVTSDEKGC-QDVDECASRASCPTGLCLNTEGSFACSACENGY 1082
Query: 999 V----GLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCL-----PGHTGQWCEVEIDP 1049
G CE D+DEC P+G C + A +F C+ P G CE ++D
Sbjct: 1083 WVNEDGTACE-DLDECAFPGVCPSGV--CTNTAGSFSCKDCDGGYRPSPLGDSCE-DVDE 1138
Query: 1050 CHS-QPCFHGGTCEATAGSPLGFICHCPKGFE---GPTCSHRAPSCGFHHCHHGGLCLPS 1105
C Q GG C+ T GS + C CP+GF+ G C G HC G CL S
Sbjct: 1139 CEDPQSSCLGGECKNTVGS---YQCLCPQGFQLANGTVCEDVNECMGEEHCAPHGECLNS 1195
Query: 1106 PKPGFPPRCACLSGY----GGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSC 1161
F C C G+ GG C C PC+ G C T G F C C
Sbjct: 1196 HGSFF---CLCAPGFVSAEGGTSCQDVDE---CATTDPCV-GGHCVNTEG----SFNCLC 1244
Query: 1162 PHS-SPGPR---------CQKPGAK-----GCEGRSGDGACDAGCSGPGGNWDGGDCSLG 1206
P P C+ G CE G C GC GDC +
Sbjct: 1245 ETGFQPSPESGECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMAPNGDC-ID 1303
Query: 1207 VPDPWKG--CPSHSRCWLLFRDGQCHPQCDSE-ECLFDGYDCETPPAC 1251
+ + C SH C DG CD E G+DC C
Sbjct: 1304 IDECANDTMCGSHGFC--DNTDGSFRCLCDQGFEISPSGWDCVDVNEC 1349
Score = 48.1 bits (113), Expect = 8e-05
Identities = 64/292 (21%), Positives = 91/292 (31%), Gaps = 51/292 (17%)
Query: 1007 VDECLDQPCHPTGTAACHSLANAFYCQCLPG---HTGQWCEVEIDPCHSQPCFHGGTCEA 1063
+D C + G C +L + + C C PG H Q + + C PC G C
Sbjct: 845 IDRCAAGATNVCGPGTCVNLPDGYRCVCSPGYQLHPSQAYCTDDNECLRDPCKGKGRCIN 904
Query: 1064 TAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGP 1123
GS + C C G+ T + C G+C C + G
Sbjct: 905 RVGS---YSCFCYPGYTLATSGATQECQDINECEQPGVCSGG---------QCTNTEGSY 952
Query: 1124 DCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRC-QKPGAKGCEGRS 1182
C C + G C + C P + P RC PG+ C
Sbjct: 953 HC-------ECDQGYIMVRKGHCQDIN-------ECRHPGTCPDGRCVNSPGSYTCL--- 995
Query: 1183 GDGACDAGCSGPGGNW-DGGDCSLGVPDPWKGCPSHSRCWLLFRDGQC-----HPQCDSE 1236
AC+ G G G+ D +C G +H +C L +C + E
Sbjct: 996 ---ACEEGYRGQSGSCVDVNECLT------PGVCAHGKCTNLEGSFRCSCEQGYEVTSDE 1046
Query: 1237 ECLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAECGWDGGDCRPED 1288
+ D +C + +C F CE G E DG C D
Sbjct: 1047 KGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNE---DGTACEDLD 1095
Score = 40.4 bits (93), Expect = 0.018
Identities = 86/335 (25%), Positives = 114/335 (34%), Gaps = 60/335 (17%)
Query: 87 PLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCS-- 144
PLG P+P T + LP G ++ P PP RGR +GR C
Sbjct: 126 PLG-QQQPAPRTRA--APALPRL-GTPQRSGAAPPTPP-----RGRL----TGRNVCGGQ 172
Query: 145 CMPGWTGEQCQ---LRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQD 201
C PGWT ++ C PC N G C + PQ+ C C GF G CE + + D
Sbjct: 173 CCPGWTTANSTNHCIKPVCEP-PCQNRGSC--SRPQL-CVCRSGFRGARCEEVIPDEEFD 228
Query: 202 P-------------GPCPKGTSC--HNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNG 246
P P + +S TL Q P P+ PP G +G
Sbjct: 229 PQNSRLAPRRWAERSPNLRRSSAAGEGTLARAQPPAPQSPPAPQ-------SPPAGTLSG 281
Query: 247 GTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQ-DGLDTYTCL-CPE 304
L S H+ L + P + + G Q DG L P
Sbjct: 282 ----LSQTHPSQQHVGLSRTVRLHPTATASSQLSSNALPPGPGLEQRDGTQQAVPLEHPS 337
Query: 305 TWTGWDCSEDVDECE-TQGPPHCRN---GGTCQNSAGSFHCVCVSGWGGTSCEENLDDCI 360
+ G + +E + + + P C+ G C NS + GG + I
Sbjct: 338 SPWGLNLTEKIKKIKIVFTPTICKQTCARGHCANSCERGDTTTLYSQGGHGHDPKSGFRI 397
Query: 361 ---AATCAPGSTCIDRVGSFSCLCPPGRTGLLCHL 392
C G CI G C CP TG CHL
Sbjct: 398 YFCQIPCLNGGRCI---GRDECWCPANSTGKFCHL 429
Score = 39.7 bits (91), Expect = 0.030
Identities = 22/65 (33%), Positives = 30/65 (46%), Gaps = 4/65 (6%)
Query: 34 PCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSS 93
PC NGG C+ G+ C C G+ C P P + + G +ALL APL +
Sbjct: 403 PCLNGGRCI----GRDECWCPANSTGKFCHLPIPQPDREPPGRGSRPRALLEAPLKQSTF 458
Query: 94 PSPLT 98
PL+
Sbjct: 459 TLPLS 463
Score = 37.4 bits (85), Expect = 0.15
Identities = 37/124 (29%), Positives = 47/124 (37%), Gaps = 23/124 (18%)
Query: 438 MAQQGPSPCEHGGSCLNTPGS--FNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLA 495
+ QQ P+P L G+ + PP R N C Q C PG T + +
Sbjct: 127 LGQQQPAPRTRAAPALPRLGTPQRSGAAPPTPPRGRLTG-RNVCGGQCC-PGWTTAN--S 182
Query: 496 TFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDEC 555
T HC+ P +CE PC N C C+C GF G RCEE I +
Sbjct: 183 TNHCIKP------VCE--------PPCQNRGSCS---RPQLCVCRSGFRGARCEEVIPDE 225
Query: 556 RSSP 559
P
Sbjct: 226 EFDP 229
Score = 37.4 bits (85), Expect = 0.15
Identities = 25/76 (32%), Positives = 32/76 (42%), Gaps = 13/76 (17%)
Query: 938 PCQNGATCMAQPSGYLC-------QCAPGYDGQNCSKEL--DACQSQPCHNHGTCTPKPG 988
P ++GA P G L QC PG+ N + C+ PC N G+C+
Sbjct: 148 PQRSGAAPPTPPRGRLTGRNVCGGQCCPGWTTANSTNHCIKPVCEP-PCQNRGSCSRPQ- 205
Query: 989 GFHCACPPGFVGLRCE 1004
C C GF G RCE
Sbjct: 206 --LCVCRSGFRGARCE 219
Score = 35.4 bits (80), Expect = 0.57
Identities = 18/41 (43%), Positives = 25/41 (60%), Gaps = 7/41 (17%)
Query: 767 STDYCVSA----PCFNGGTCVNRPGTFSCLCAMGFQGPRCE 803
ST++C+ PC N G+C +RP C+C GF+G RCE
Sbjct: 182 STNHCIKPVCEPPCQNRGSC-SRPQL--CVCRSGFRGARCE 219
Score = 33.1 bits (74), Expect = 2.8
Identities = 119/498 (23%), Positives = 155/498 (31%), Gaps = 148/498 (29%)
Query: 34 PCANGGTCLSLSLGQGTCQCAPGFLGETCQ--FPDP---CQNAQLCQN------------ 76
PC N G+C L C C GF G C+ PD QN++L
Sbjct: 194 PCQNRGSCSRPQL----CVCRSGFRGARCEEVIPDEEFDPQNSRLAPRRWAERSPNLRRS 249
Query: 77 -----GGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRG 131
G +A PAP P+ SP P+ + L + L S+
Sbjct: 250 SAAGEGTLARAQPPAPQSPPAPQSP--PAGTLSGLSQTHPSQQHVGL---------SRTV 298
Query: 132 RCHIQASGRPQCSCMPGWTGEQCQLRDFCSA-----NPCVNGGVCLA--------TYPQI 178
R H A+ Q S G + RD +P G+ L +
Sbjct: 299 RLHPTATASSQLSSNALPPGPGLEQRDGTQQAVPLEHPSSPWGLNLTEKIKKIKIVFTPT 358
Query: 179 QCH--CPPGFEGHACER-DVNECFQDPG----------------PCPKGTSCHNTLGSFQ 219
C C G ++CER D + G PC G C +G +
Sbjct: 359 ICKQTCARGHCANSCERGDTTTLYSQGGHGHDPKSGFRIYFCQIPCLNGGRC---IGRDE 415
Query: 220 CLCPVGQEGPRCEL---RAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCP------PGFIG 270
C CP G C L + PP S P K STF L L P +
Sbjct: 416 CWCPANSTGKFCHLPIPQPDREPPGRGSRPRALLEAPLKQSTFTLPLSNQLASVNPSLVK 475
Query: 271 PDCEVNPDNCVS-HQCQN--GGTCQDGLDTYTCLCPETWTG-------WDCSEDVDECET 320
P+ V HQ GG + ++ P W WD S ++
Sbjct: 476 VHIHHPPEASVQIHQVAQVRGGVEEALVENSVETRPPPWLPASPGHSLWD-SNNIPARSG 534
Query: 321 QGP-------PHCRN----------GGTCQN-------------SAGSFHCVCVSGWGGT 350
+ P P R G C N S G+F WG T
Sbjct: 535 EPPRPLPPAAPRPRGLLGRCYLNTVNGQCANPLLELTTQEDCCGSVGAF-------WGVT 587
Query: 351 SCEENLDDCIAATCAP--GSTCIDRVGSFSCLCPPGRTGL-LCHLEDM--CLSQPCHGDA 405
C A C P S I+ G C P G L L H +D+ CL+ DA
Sbjct: 588 LC---------APCPPRPASPVIEN-GQLEC--PQGYKRLNLTHCQDINECLTLGLCKDA 635
Query: 406 QCSTNPLTGSTLCLCQPG 423
+C GS LC C+PG
Sbjct: 636 ECVNT--RGSYLCTCRPG 651
Score = 32.3 bits (72), Expect = 4.8
Identities = 17/51 (33%), Positives = 26/51 (50%), Gaps = 4/51 (7%)
Query: 918 CPPGFQGSLCQDH-VNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSK 967
C PG+ + +H + P PCQN +C ++P LC C G+ G C +
Sbjct: 173 CCPGWTTANSTNHCIKPVCEPPCQNRGSC-SRPQ--LCVCRSGFRGARCEE 220
Score = 32.3 bits (72), Expect = 4.8
Identities = 124/580 (21%), Positives = 169/580 (29%), Gaps = 167/580 (28%)
Query: 808 PSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQT-LMDLCAQKPCPRNSHCLQTGPSF 866
P+ + P R P+G C G C L++L Q+ C C G
Sbjct: 530 PARSGEPPRPLPPAAPRPRGLLGRCYLNTVNGQCANPLLELTTQEDC-----CGSVGAF- 583
Query: 867 HCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQG-- 924
W LC + C S I+ NG L CP G++
Sbjct: 584 -------WGVTLC----APCPPRPASPVIE------NGQL----------ECPQGYKRLN 616
Query: 925 -SLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGY----DGQNCSKELDACQSQP-CH 978
+ CQD +N C + A C+ YLC C PG C + Q C+
Sbjct: 617 LTHCQD-INECLTLGLCKDAECVNTRGSYLCTCRPGLMLDPSRSRCVSDKAISMLQGLCY 675
Query: 979 NH---GTCT----------------------------PKPG--GFHCACPPGFVGLRCEG 1005
GTCT P PG F CP G
Sbjct: 676 RSLGPGTCTLPLAQRITKQICCCSRVGKAWGSECEKCPLPGTEAFREICPAGHGYTYASS 735
Query: 1006 DV--------DECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFH 1057
D+ +E L +P G + +L Q L T W E P
Sbjct: 736 DIRLSMRKAEEEELARPPREQGQRSSGALPGPAERQPLRVVTDTWLEAGTIPDKG----- 790
Query: 1058 GGTCEATAGSPLGFICHCPKGFEGPTCSHRAP-----------------------SCGFH 1094
++ AG + H P G + P + G
Sbjct: 791 ----DSQAGQVTTSVTHAPAWVTGNATTPPMPEQGIAEIQEEQVTPSTDVLVTLSTPGID 846
Query: 1095 HCHHG--GLCLPSPKPGFPP--RCACLSGYGGPDCLTPPAPKGCGPPS-----PCLYNGS 1145
C G +C P P RC C GY P+ C + PC G
Sbjct: 847 RCAAGATNVCGPGTCVNLPDGYRCVCSPGY-----QLHPSQAYCTDDNECLRDPCKGKGR 901
Query: 1146 CSETTGLGGPGFRCSCPHSSPGPRCQKPGA-KGCEGRS---GDGACDAG-CSGPGGNWDG 1200
C G + C C PG GA + C+ + G C G C+ G++
Sbjct: 902 CINRVG----SYSCFC---YPGYTLATSGATQECQDINECEQPGVCSGGQCTNTEGSYH- 953
Query: 1201 GDCSLGVPDPWKG-CPSHSRCWL--LFRDGQCHPQCDSEECLF--DGY-----------D 1244
+C G KG C + C DG+C S CL +GY +
Sbjct: 954 CECDQGYIMVRKGHCQDINECRHPGTCPDGRCVNSPGSYTCLACEEGYRGQSGSCVDVNE 1013
Query: 1245 CETPPACT--------PAYDQYCHDHFHNGHCEKGCNTAE 1276
C TP C ++ C + EKGC +
Sbjct: 1014 CLTPGVCAHGKCTNLEGSFRCSCEQGYEVTSDEKGCQDVD 1053
Score = 31.6 bits (70), Expect = 8.2
Identities = 21/63 (33%), Positives = 28/63 (44%), Gaps = 10/63 (15%)
Query: 539 CLPGF----SGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECL 594
C PG+ S C + + E PC N G C +P C C GF G RC+ + +
Sbjct: 173 CCPGWTTANSTNHCIKPVCE---PPCQNRGSCS-RPQL--CVCRSGFRGARCEEVIPDEE 226
Query: 595 SDP 597
DP
Sbjct: 227 FDP 229
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 247 bits (630), Expect = 9e-65
Identities = 212/722 (29%), Positives = 273/722 (37%), Gaps = 154/722 (21%)
Query: 103 CTCLPGFTGERCQAKLEDPCPPSF-----------CSKRGRCHIQASGRPQCSCMPGWTG 151
C+C PG+ G C + PPS C+ +GRC R +C C PG+TG
Sbjct: 156 CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCV-----RGRCVCFPGYTG 210
Query: 152 EQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSC 211
C C + C G C+ Q C C GF G C + CP+G S
Sbjct: 211 PSCGWPS-CPGD-CQGRGRCV----QGVCVCRAGFSGPDCSQR---------SCPRGCSQ 255
Query: 212 HNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGP 271
+C+C G G C +R+ CP RGCS G C+ C+C PG+ G
Sbjct: 256 RGRCEGGRCVCDPGYTGDDCGMRS--CP-RGCSQRGRCEN--------GRCVCNPGYTGE 304
Query: 272 DCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGT 331
DC V +C C G C+DG C+C +TG DC C P C GG
Sbjct: 305 DCGVR--SC-PRGCSQRGRCKDG----RCVCDPGYTGEDCG--TRSC----PWDCGEGGR 351
Query: 332 CQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCH 391
C + CVC G+ G +DC TC R C+C G +G
Sbjct: 352 CVDG----RCVCWPGYTG-------EDCSTRTCPRDCRGRGRCEDGECICDTGYSG---- 396
Query: 392 LEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGS 451
D C + C GD C+ C+C PGY+G C ++ P C G
Sbjct: 397 --DDCGVRSCPGD--CNQRGRCEDGRCVCWPGYTGTDCG--------SRACPRDCRGRGR 444
Query: 452 CLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCE 511
C N C+C GY+G C C C C + C+C PG G+ C
Sbjct: 445 CENGV----CVCNAGYSGEDCGV--RSCPGD-CRGRGRC----ESGRCMCWPGYTGRDCG 493
Query: 512 VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSP--CANGGQCQDQ 569
T C C C D +C+C PGF+G C R P C G C+D
Sbjct: 494 --TRACPG-DCRGRGRCVD----GRCVCNPGFTGEDCGS-----RRCPGDCRGHGLCEDG 541
Query: 570 PGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGA----SCLDLPGAFFCLCPSGFTGQLCE 625
C C G+ G C T CP G CLD C+C G++G+ C
Sbjct: 542 V----CVCDAGYSGEDCSTR-------SCPGGCRGRGQCLDGR----CVCEDGYSGEDCG 586
Query: 626 VPLCAPNLCQPKQICKDQKDKANCLCPDG--SPGCAPPEDNCTCH-HGHCQRSSCVCDVG 682
V C PN C +C+D C+C +G S C+ CH G C+ C+CD G
Sbjct: 587 VRQC-PNDCSQHGVCQD----GVCICWEGYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPG 641
Query: 683 WTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGG 742
+TGP C + A C G C C C GY G C +E + P G
Sbjct: 642 YTGPTCATRM---CPADCRGRGRCVQGV----CLCHVGYGGEDCGQEEPPASACP----G 690
Query: 743 SCNPSP--GGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGP 800
C P C C GP C T C G C + SC+C G+ G
Sbjct: 691 GCGPRELCRAGQCVCVEGFRGPDCAIQT---CPGDCRGRGECHDG----SCVCKDGYAGE 743
Query: 801 RC 802
C
Sbjct: 744 DC 745
Score = 241 bits (616), Expect = 4e-63
Identities = 207/681 (30%), Positives = 280/681 (41%), Gaps = 133/681 (19%)
Query: 29 GSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPD---PCQNAQLCQNGGS-CQALL 84
GS P+ C + G C+ +G C C PG+ G +C +P CQ C G C+A
Sbjct: 185 GSCPDDCNDQGRCV-----RGRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGF 239
Query: 85 PAP-LGLPSSPSPLTP-----SFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQAS 138
P S P + C C PG+TG+ C + CP CS+RGRC +
Sbjct: 240 SGPDCSQRSCPRGCSQRGRCEGGRCVCDPGYTGDDCGMR---SCPRG-CSQRGRCE---N 292
Query: 139 GRPQCSCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNEC 198
GR C C PG+TGE C +R C G C +C C PG+ G C C
Sbjct: 293 GR--CVCNPGYTGEDCGVRS--CPRGCSQRGRC----KDGRCVCDPGYTGEDC--GTRSC 342
Query: 199 FQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDST 258
P C +G C + +C+C G G C R CP R C G C+ D
Sbjct: 343 ---PWDCGEGGRCVDG----RCVCWPGYTGEDCSTRT--CP-RDCRGRGRCE-----DGE 387
Query: 259 FHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDEC 318
C+C G+ G DC V +C C G C+DG C+C +TG DC C
Sbjct: 388 ---CICDTGYSGDDCGVR--SCPG-DCNQRGRCEDG----RCVCWPGYTGTDCGSRA--C 435
Query: 319 ETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFS 378
P CR G C+N CVC +G+ G +DC +C R S
Sbjct: 436 ----PRDCRGRGRCENGV----CVCNAGYSG-------EDCGVRSCPGDCRGRGRCESGR 480
Query: 379 CLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLM 438
C+C PG TG C ++ C GD + + G C+C PG++G C
Sbjct: 481 CMCWPGYTGRDCG------TRACPGDCRGRGRCVDGR--CVCNPGFTGEDCG-------- 524
Query: 439 AQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFH 498
+++ P C G C + C+C GY+G C C CLD
Sbjct: 525 SRRCPGDCRGHGLCEDGV----CVCDAGYSGEDCST---RSCPGGCRGRGQCLD----GR 573
Query: 499 CLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSS 558
C+C G G+ C V +C + C H C D + CIC G+ C I C S+
Sbjct: 574 CVCEDGYSGEDCGVR--QCPN-DCSQHGVCQDGV----CICWEGYVSEDCS--IRTCPSN 624
Query: 559 PCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSG 618
C G+C++ C C PG+ GP C T + C +D C C+ CLC G
Sbjct: 625 -CHGRGRCEEG----RCLCDPGYTGPTCATRM--CPAD-CRGRGRCVQ----GVCLCHVG 672
Query: 619 FTGQLC---EVPLCA-PNLCQPKQICKDQKDKANCLCPDG--SPGCAPPEDNCTCH-HGH 671
+ G+ C E P A P C P+++C+ C+C +G P CA C G
Sbjct: 673 YGGEDCGQEEPPASACPGGCGPRELCR----AGQCVCVEGFRGPDCAIQTCPGDCRGRGE 728
Query: 672 CQRSSCVCDVGWTGPECEAEL 692
C SCVC G+ G +C E+
Sbjct: 729 CHDGSCVCKDGYAGEDCGEEV 749
Score = 238 bits (606), Expect = 6e-62
Identities = 210/755 (27%), Positives = 278/755 (36%), Gaps = 148/755 (19%)
Query: 105 CLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSANP 164
C G QA + CS G + R CSC PGW G C P
Sbjct: 121 CTGGCCPASAQAGTGQTDVRTLCSLHGVFDLS---RCTCSCEPGWGGPTCSDPTDAEIPP 177
Query: 165 -------------CVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSC 211
C + G C+ +C C PG+ G +C C PG C C
Sbjct: 178 SSPPSASGSCPDDCNDQGRCVRG----RCVCFPGYTGPSCGWP--SC---PGDCQGRGRC 228
Query: 212 HNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGP 271
+ C+C G GP C R+ CP RGCS G C+ C+C PG+ G
Sbjct: 229 VQGV----CVCRAGFSGPDCSQRS--CP-RGCSQRGRCE--------GGRCVCDPGYTGD 273
Query: 272 DCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGT 331
DC + +C C G C++G C+C +TG DC V C P C G
Sbjct: 274 DCGMR--SC-PRGCSQRGRCENG----RCVCNPGYTGEDCG--VRSC----PRGCSQRGR 320
Query: 332 CQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCH 391
C++ CVC G+ G C C G C+D C+C PG TG C
Sbjct: 321 CKDG----RCVCDPGYTGEDCGTR---SCPWDCGEGGRCVDG----RCVCWPGYTGEDCS 369
Query: 392 LEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGS 451
+ C G +C C+C GYSG C + P C G
Sbjct: 370 TRTC--PRDCRGRGRCEDGE------CICDTGYSGDDCG--------VRSCPGDCNQRGR 413
Query: 452 CLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCE 511
C + C+C PGYTG+ C + + C C + + C+C G G+ C
Sbjct: 414 CEDG----RCVCWPGYTGTDCGS---RACPRDCRGRGRCENGV----CVCNAGYSGEDCG 462
Query: 512 VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSP--CANGGQCQDQ 569
V + C C +C+C PG++G C R+ P C G+C D
Sbjct: 463 VRS---CPGDCRGRGRCES----GRCMCWPGYTGRDCGT-----RACPGDCRGRGRCVDG 510
Query: 570 PGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLC 629
C C PGF G ++C S CP L C+C +G++G+ C C
Sbjct: 511 ----RCVCNPGFTG-------EDCGSRRCPGDCRGHGLCEDGVCVCDAGYSGEDCSTRSC 559
Query: 630 APNLCQPKQICKDQKDKANCLCPDGSPG--CAPPEDNCTC-HHGHCQRSSCVCDVGWTGP 686
P C+ + C D + C+C DG G C + C HG CQ C+C G+
Sbjct: 560 -PGGCRGRGQCLDGR----CVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSE 614
Query: 687 ECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNP 746
+C + C G C C C GYTGPTC+ M C G C
Sbjct: 615 DCSIRT---CPSNCHGRGRCEEG----RCLCDPGYTGPTCATRMCPAD---CRGRGRCVQ 664
Query: 747 SPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKL 806
C C + G C + P G + R G C+C GF+GP C +
Sbjct: 665 G----VCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAG--QCVCVEGFRGPDCAIQT 718
Query: 807 RPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSC 841
P CR R C D C+C GY G C
Sbjct: 719 CPG----DCRGRGECHDGS----CVCKDGYAGEDC 745
Score = 219 bits (558), Expect = 2e-56
Identities = 197/702 (28%), Positives = 260/702 (37%), Gaps = 163/702 (23%)
Query: 341 CVCVSGWGGTSCEENLDDCIAATCAPGST------CID--RVGSFSCLCPPGRTGLLCHL 392
C C GWGG +C + D I + P ++ C D R C+C PG TG C
Sbjct: 156 CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGW 215
Query: 393 EDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSC 452
C GD Q + G +C+C+ G+SGP C Q + P C G C
Sbjct: 216 PS------CPGDCQGRGRCVQG--VCVCRAGFSGPDCSQ--------RSCPRGCSQRGRC 259
Query: 453 LNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEV 512
C+C PGYTG ++C + C G + C+C PG G+ C V
Sbjct: 260 EGG----RCVCDPGYTG-------DDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCGV 308
Query: 513 ETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSP--CANGGQCQDQP 570
+ C C D +C+C PG++G C RS P C GG+C D
Sbjct: 309 RS---CPRGCSQRGRCKD----GRCVCDPGYTGEDCGT-----RSCPWDCGEGGRCVDG- 355
Query: 571 GAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCA 630
C C PG+ G C T C D C C D C+C +G++G C V C
Sbjct: 356 ---RCVCWPGYTGEDCSTRT--CPRD-CRGRGRCEDGE----CICDTGYSGDDCGVRSC- 404
Query: 631 PNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCT--CH-HGHCQRSSCVCDVGWTGPE 687
P C + C+D + C+C G G C C G C+ CVC+ G++G +
Sbjct: 405 PGDCNQRGRCEDGR----CVCWPGYTGTDCGSRACPRDCRGRGRCENGVCVCNAGYSGED 460
Query: 688 CEAELGGCISAP--CAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCN 745
C G S P C G C SG C C GYTG C AC G C G C
Sbjct: 461 C-----GVRSCPGDCRGRGRC---ESG-RCMCWPGYTGRDCGTR--AC-PGDCRGRGRCV 508
Query: 746 PSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGK 805
C C P TG C + C G C + C+C G+ G C +
Sbjct: 509 DGR----CVCNPGFTGEDCGSRR---CPGDCRGHGLCEDGV----CVCDAGYSGEDCSTR 557
Query: 806 LRPSCADSPCRNRATCQDSPQGPRCLCPTGYTG---------------GSCQT------- 843
P CR R C D RC+C GY+G G CQ
Sbjct: 558 SCPG----GCRGRGQCLDG----RCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWE 609
Query: 844 --LMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLC 901
+ + C+ + CP N H CLC G+TGP C + + + LC
Sbjct: 610 GYVSEDCSIRTCPSNCHGRGRCEEGRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLC 669
Query: 902 HNG-----------------GLCVDSGPSYFCH-----CPPGFQGSLCQDHVNPCESR-- 937
H G G C GP C C GF+G C P + R
Sbjct: 670 HVGYGGEDCGQEEPPASACPGGC---GPRELCRAGQCVCVEGFRGPDCAIQTCPGDCRGR 726
Query: 938 -PCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCH 978
C +G+ C C GY G++C +E+ + H
Sbjct: 727 GECHDGS----------CVCKDGYAGEDCGEEVPTIEGMRMH 758
Score = 218 bits (555), Expect = 5e-56
Identities = 216/812 (26%), Positives = 285/812 (35%), Gaps = 191/812 (23%)
Query: 176 PQIQCHCPPGFEGHACERDVN------ECFQD----------PGPCPKGT---------- 209
P C CPPG E +V E ++ G CP
Sbjct: 81 PSTGCGCPPGTEPPVLASEVQALRVRLEILEELVKGLKEQCTGGCCPASAQAGTGQTDVR 140
Query: 210 ---SCHNT--LGSFQCLCPVGQEGPRCE-------------LRAGPCPPRGCSNGGTCQL 251
S H L C C G GP C +G CP C++ G C
Sbjct: 141 TLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPD-DCNDQGRC-- 197
Query: 252 MPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDC 311
C+C PG+ GP C +C CQ G C G+ C+C ++G DC
Sbjct: 198 ------VRGRCVCFPGYTGPSC--GWPSCPG-DCQGRGRCVQGV----CVCRAGFSGPDC 244
Query: 312 SEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCI 371
S + P C G C+ CVC G+ G DDC +C G +
Sbjct: 245 S------QRSCPRGCSQRGRCEGG----RCVCDPGYTG-------DDCGMRSCPRGCSQR 287
Query: 372 DRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQ 431
R + C+C PG TG ED C + C CS C+C PGY+G C
Sbjct: 288 GRCENGRCVCNPGYTG-----ED-CGVRSC--PRGCSQRGRCKDGRCVCDPGYTGEDCG- 338
Query: 432 DLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCL 491
+ P C GG C++ C+C PGYTG C + C C
Sbjct: 339 -------TRSCPWDCGEGGRCVDG----RCVCWPGYTGEDCS---TRTCPRDCRGRGRCE 384
Query: 492 DLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEED 551
D C+C G G C V + C C D +C+C PG++GT C
Sbjct: 385 D----GECICDTGYSGDDCGVRS---CPGDCNQRGRCED----GRCVCWPGYTGTDCGS- 432
Query: 552 IDECRSSP--CANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPG 609
R+ P C G+C++ C C G+ G C V C D C C
Sbjct: 433 ----RACPRDCRGRGRCENGV----CVCNAGYSGEDC--GVRSCPGD-CRGRGRC----E 477
Query: 610 AFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG--CAPPEDNCTC 667
+ C+C G+TG+ C C P C+ + C D C+C G G C C
Sbjct: 478 SGRCMCWPGYTGRDCGTRAC-PGDCRGRGRCVD----GRCVCNPGFTGEDCGSRRCPGDC 532
Query: 668 H-HGHCQRSSCVCDVGWTGPECEAEL--GGCIS-APCAHGGTCYPQPSGYNCTCPTGYTG 723
HG C+ CVCD G++G +C GGC C G C C GY+G
Sbjct: 533 RGHGLCEDGVCVCDAGYSGEDCSTRSCPGGCRGRGQCLDG----------RCVCEDGYSG 582
Query: 724 PTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCV 783
C C G C C C + C T C S C G C
Sbjct: 583 EDCGVRQC---PNDCSQHGVCQDG----VCICWEGYVSEDCSIRT--CPS-NCHGRGRCE 632
Query: 784 NRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQT 843
CLC G+ GP C ++ P + CR R C CLC GY G C
Sbjct: 633 EG----RCLCDPGYTGPTCATRMCP----ADCRGRGRCVQGV----CLCHVGYGGEDCG- 679
Query: 844 LMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHN 903
+ CP + + C+C++G+ GP C + +C +G CH+
Sbjct: 680 -QEEPPASACPGGCGPRELCRAGQCVCVEGFRGPDC--AIQTCPGDCRGRG-----ECHD 731
Query: 904 GGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCE 935
G C C G+ G C + V E
Sbjct: 732 GS----------CVCKDGYAGEDCGEEVPTIE 753
Score = 216 bits (549), Expect = 2e-55
Identities = 218/818 (26%), Positives = 277/818 (33%), Gaps = 196/818 (23%)
Query: 376 SFSCLCPPGRTG-------------------LLCHLEDMCLSQPCHGDAQCSTNPLTGST 416
S C CPPG L+ L++ C C AQ T T
Sbjct: 82 STGCGCPPGTEPPVLASEVQALRVRLEILEELVKGLKEQCTGGCCPASAQAGTGQTDVRT 141
Query: 417 LCL-------------CQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLC 463
LC C+PG+ GPTC D A+ PS
Sbjct: 142 LCSLHGVFDLSRCTCSCEPGWGGPTCSDPTD----AEIPPSS------------------ 179
Query: 464 PPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCL 523
PP +GS C D C+ C+ C+C PG G C + C
Sbjct: 180 PPSASGS-CPDD--------CNDQGRCV----RGRCVCFPGYTGPSCGWPS---CPGDCQ 223
Query: 524 NHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSP--CANGGQCQDQPGAFHCKCLPGF 581
C + G C+C GFSG C + RS P C+ G+C+ C C PG+
Sbjct: 224 GRGRC---VQGV-CVCRAGFSGPDCSQ-----RSCPRGCSQRGRCEGG----RCVCDPGY 270
Query: 582 EGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICK 641
G D+C CP G S C+C G+TG+ C V C P C + CK
Sbjct: 271 TG-------DDCGMRSCPRGCSQRGRCENGRCVCNPGYTGEDCGVRSC-PRGCSQRGRCK 322
Query: 642 DQKDKANCLCPDGSPG--CAPPEDNCTCHHG-HCQRSSCVCDVGWTGPECEAELGGCISA 698
D + C+C G G C C G C CVC G+TG +C
Sbjct: 323 DGR----CVCDPGYTGEDCGTRSCPWDCGEGGRCVDGRCVCWPGYTGEDCSTRT---CPR 375
Query: 699 PCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPS 758
C G C C C TGY+G C + +C G C G C C C P
Sbjct: 376 DCRGRGRC----EDGECICDTGYSGDDCG--VRSC-PGDCNQRGRCEDGR----CVCWPG 424
Query: 759 HTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNR 818
+TG C + C G C N C+C G+ G C + P CR R
Sbjct: 425 YTGTDCGSRA---CPRDCRGRGRCENGV----CVCNAGYSGEDCGVRSCPG----DCRGR 473
Query: 819 ATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPL 878
C+ RC+C GYTG C T + CP + C+C G+TG
Sbjct: 474 GRCESG----RCMCWPGYTGRDCGT-------RACPGDCRGRGRCVDGRCVCNPGFTGED 522
Query: 879 CNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRP 938
C C GLC D C C G+ G C +R
Sbjct: 523 CGSRRCPGD-------------CRGHGLCEDG----VCVCDAGYSGE-------DCSTRS 558
Query: 939 CQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGF 998
C G Q C C GY G++C + C + C HG C C C G+
Sbjct: 559 CPGGCRGRGQCLDGRCVCEDGYSGEDCG--VRQCPND-CSQHGVCQDGV----CICWEGY 611
Query: 999 VGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHG 1058
V C + C CH G C C C PG+TG C + P C
Sbjct: 612 VSEDCS--IRTCPSN-CH--GRGRCEEGR----CLCDPGYTGPTCATRMCPAD---CRGR 659
Query: 1059 GTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGF--HHCHHGGLCLPSPKPGFPPRCAC 1116
G C + +C C G+ G C P C LC +C C
Sbjct: 660 GRC-------VQGVCLCHVGYGGEDCGQEEPPASACPGGCGPRELCRAG-------QCVC 705
Query: 1117 LSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGG 1154
+ G+ GPDC P C C ++GSC G G
Sbjct: 706 VEGFRGPDCAIQTCPGDCRGRGEC-HDGSCVCKDGYAG 742
Score = 193 bits (491), Expect = 1e-48
Identities = 218/801 (27%), Positives = 269/801 (33%), Gaps = 215/801 (26%)
Query: 570 PGAFHCKCLPGFEGPRCQTEV------------------DECLSDPCPVGA--------- 602
P + C C PG E P +EV ++C CP A
Sbjct: 80 PPSTGCGCPPGTEPPVLASEVQALRVRLEILEELVKGLKEQCTGGCCPASAQAGTGQTDV 139
Query: 603 -SCLDLPGAF-----FCLCPSGFTGQLC------EVPLCAPNLCQPK--QICKDQKD--K 646
+ L G F C C G+ G C E+P +P C DQ +
Sbjct: 140 RTLCSLHGVFDLSRCTCSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVR 199
Query: 647 ANCLCPDG--SPGCAPPEDNCTCH-HGHCQRSSCVCDVGWTGPECEAELGGCISAP--CA 701
C+C G P C P C G C + CVC G++GP+C S P C+
Sbjct: 200 GRCVCFPGYTGPSCGWPSCPGDCQGRGRCVQGVCVCRAGFSGPDCSQR-----SCPRGCS 254
Query: 702 HGGTCYPQPSGYNCTCPTGYTGPTCSEEMTAC-----HSGPCLNGGS-CNPSPGGY---- 751
G C G C C GYTG C M +C G C NG CNP G
Sbjct: 255 QRGRC----EGGRCVCDPGYTGDDCG--MRSCPRGCSQRGRCENGRCVCNPGYTGEDCGV 308
Query: 752 ----------------YCTCPPSHTGPQCQTSTDYCVSAP--CFNGGTCVNRPGTFSCLC 793
C C P +TG C T S P C GG CV+ C+C
Sbjct: 309 RSCPRGCSQRGRCKDGRCVCDPGYTGEDCGTR-----SCPWDCGEGGRCVDG----RCVC 359
Query: 794 AMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPC 853
G+ G C + P CR R C+D C+C TGY+G D C + C
Sbjct: 360 WPGYTGEDCSTRTCP----RDCRGRGRCEDG----ECICDTGYSG-------DDCGVRSC 404
Query: 854 PRNSHCLQTG--PSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSG 911
P C Q G C+C G+TG C +C + +G C NG
Sbjct: 405 P--GDCNQRGRCEDGRCVCWPGYTGTDCG--SRACPRDCRGRG-----RCENG------- 448
Query: 912 PSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDA 971
C C G+ G C R C + C C PGY G++C A
Sbjct: 449 ---VCVCNAGYSG-------EDCGVRSCPGDCRGRGRCESGRCMCWPGYTGRDCGTR--A 496
Query: 972 CQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFY 1031
C C G C C C PGF G ++C + C G H L
Sbjct: 497 CPGD-CRGRGRCVDG----RCVCNPGFTG-------EDCGSRRC--PGDCRGHGLCEDGV 542
Query: 1032 CQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSC 1091
C C G++G+ C P G C G L C C G+ G C R C
Sbjct: 543 CVCDAGYSGEDCSTRSCP---------GGCRG-RGQCLDGRCVCEDGYSGEDCGVR--QC 590
Query: 1092 GFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTG 1151
+ C G+C C C GY DC + + C PS C G C E
Sbjct: 591 P-NDCSQHGVCQDGV-------CICWEGYVSEDC----SIRTC--PSNCHGRGRCEEG-- 634
Query: 1152 LGGPGFRCSCPHSSPGPRC-QKPGAKGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDP 1210
RC C GP C + C GR G C G + G DC P P
Sbjct: 635 ------RCLCDPGYTGPTCATRMCPADCRGR---GRCVQGVCLCHVGYGGEDCGQEEP-P 684
Query: 1211 WKGCPSHSRCWLLFRDGQCHPQCDSEECL--FDGYDC--ETPPACTPAYDQYCHDHFHNG 1266
CP L R GQC C+ F G DC +T P D G
Sbjct: 685 ASACPGGCGPRELCRAGQC-------VCVEGFRGPDCAIQTCPG----------DCRGRG 727
Query: 1267 HCEKGCNTAECGWDGGDCRPE 1287
C G + G+ G DC E
Sbjct: 728 ECHDGSCVCKDGYAGEDCGEE 748
Score = 172 bits (435), Expect = 4e-42
Identities = 179/619 (28%), Positives = 220/619 (35%), Gaps = 137/619 (22%)
Query: 715 CTCPTGYTGPTCSEEMTA--CHSGPCLNGGSCNPSPGGY------YCTCPPSHTGPQCQT 766
C+C G+ GPTCS+ A S P GSC C C P +TGP C
Sbjct: 156 CSCEPGWGGPTCSDPTDAEIPPSSPPSASGSCPDDCNDQGRCVRGRCVCFPGYTGPSCGW 215
Query: 767 STDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQ 826
+ C G CV C+C GF GP C + P C R C+
Sbjct: 216 PS---CPGDCQGRGRCVQGV----CVCRAGFSGPDCSQRSCPR----GCSQRGRCE---- 260
Query: 827 GPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTG--PSFHCLCLQGWTGPLCNLPLS 884
G RC+C GYTG D C + CPR C Q G + C+C G+TG C +
Sbjct: 261 GGRCVCDPGYTG-------DDCGMRSCPRG--CSQRGRCENGRCVCNPGYTGEDCG--VR 309
Query: 885 SCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGAT 944
SC + C G C D C C PG+ G C P + C G
Sbjct: 310 SCPRG-----------CSQRGRCKDGR----CVCDPGYTGEDCGTRSCPWD---CGEGGR 351
Query: 945 CMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCE 1004
C+ C C PGY G++CS C + C G C C C G+ G
Sbjct: 352 CV----DGRCVCWPGYTGEDCSTR--TC-PRDCRGRGRCEDG----ECICDTGYSG---- 396
Query: 1005 GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEAT 1064
D+C + C G C C PG+TG C P + C G CE
Sbjct: 397 ---DDCGVRSC--PGDCNQRGRCEDGRCVCWPGYTGTDCGSRACP---RDCRGRGRCE-- 446
Query: 1065 AGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPD 1124
+C C G+ G C R SC C G C RC C GY G D
Sbjct: 447 -----NGVCVCNAGYSGEDCGVR--SCP-GDCRGRGRCESG-------RCMCWPGYTGRD 491
Query: 1125 CLTPPAPKGCGPPSPCLYNGSCSETTGLGGP--GFRCSCPHSSPGPRCQKPGAKGCE-GR 1181
C T P C C+ +G C G G G R CP G + G C+ G
Sbjct: 492 CGTRACPGDCRGRGRCV-DGRCVCNPGFTGEDCGSR-RCPGDCRGHGLCEDGVCVCDAGY 549
Query: 1182 SGDG----ACDAGCSGPGGNWDG-------------------------GDCSLGVPDPWK 1212
SG+ +C GC G G DG G C GV W+
Sbjct: 550 SGEDCSTRSCPGGCRGRGQCLDGRCVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWE 609
Query: 1213 GCPSHSRCWLLFRDGQCH--PQCDSEECLFD-GYDCETPPACTPAYDQYCHDHFHNGHCE 1269
G S C + CH +C+ CL D GY T P C A D G C
Sbjct: 610 GYVSED-CSIRTCPSNCHGRGRCEEGRCLCDPGY---TGPTC--ATRMCPADCRGRGRCV 663
Query: 1270 KGCNTAECGWDGGDCRPED 1288
+G G+ G DC E+
Sbjct: 664 QGVCLCHVGYGGEDCGQEE 682
Score = 109 bits (272), Expect = 3e-23
Identities = 93/317 (29%), Positives = 118/317 (37%), Gaps = 80/317 (25%)
Query: 28 CGS--FPEPCANGGTCLSLSLGQGTCQCAPGFLGETC---QFPDPCQNAQLCQNGGSCQA 82
CG+ P C G C+ G C C PGF GE C + P C+ LC++G
Sbjct: 492 CGTRACPGDCRGRGRCVD-----GRCVCNPGFTGEDCGSRRCPGDCRGHGLCEDG----- 541
Query: 83 LLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQ 142
+C C G++GE C + CP C RG+C GR
Sbjct: 542 -------------------VCVCDAGYSGEDCSTR---SCPGG-CRGRGQC---LDGR-- 573
Query: 143 CSCMPGWTGEQCQLRDF---CSANPCVNGGVCLAT--YPQIQCH---CPPGFEGHA-CER 193
C C G++GE C +R CS + GVC+ Y C CP G CE
Sbjct: 574 CVCEDGYSGEDCGVRQCPNDCSQHGVCQDGVCICWEGYVSEDCSIRTCPSNCHGRGRCEE 633
Query: 194 DVNECFQDPG---------PCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCP--PRG 242
C DPG CP CLC VG G C P P G
Sbjct: 634 --GRCLCDPGYTGPTCATRMCPADCRGRGRCVQGVCLCHVGYGGEDCGQEEPPASACPGG 691
Query: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLC 302
C C+ C+C GF GPDC + C C+ G C DG +C+C
Sbjct: 692 CGPRELCRAGQ--------CVCVEGFRGPDCAIQ--TCPG-DCRGRGECHDG----SCVC 736
Query: 303 PETWTGWDCSEDVDECE 319
+ + G DC E+V E
Sbjct: 737 KDGYAGEDCGEEVPTIE 753
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 240 bits (613), Expect = 9e-63
Identities = 237/840 (28%), Positives = 297/840 (35%), Gaps = 226/840 (26%)
Query: 112 ERCQAKLEDP--CPPSFCSKRG--RCHIQASGRPQCSCMPGWTGEQCQLRDFC---SANP 164
E C+ E P CP R R ++ R + C G+ + R FC A
Sbjct: 53 EPCERPWEGPHTCPQPTVVYRTVYRQVVKTDHRQRLQCCHGFY----ESRGFCVPLCAQE 108
Query: 165 CVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLG----SFQC 220
CV+G C+A QC C PG+ G C + P C K SC N S C
Sbjct: 109 CVHGR-CVAPN---QCQCVPGWRGDDCSSECAPGMWGP-QCDKPCSCGNNSSCDPKSGVC 163
Query: 221 LCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNC 280
CP G + P C L P C PG+ GP C+ C
Sbjct: 164 SCPSGLQPPNC-------------------LQP----------CTPGYYGPACQFR---C 191
Query: 281 VSHQCQNGGTCQDGLDTYTCLCPETWTG----WDCSEDVDECETQGPPHCRNGGTCQNSA 336
H G C T C CP TG CS+ C+NGG Q
Sbjct: 192 QCH----GAPCDP--QTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQ 245
Query: 337 GSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMC 396
GS C C GW GT C S CP G G C E C
Sbjct: 246 GS--CSCPPGWMGTIC-------------------------SLPCPEGFHGPNCSQECRC 278
Query: 397 LSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTP 456
H C TG C C PGY+G C ++ Q C+ P
Sbjct: 279 -----HNGGLCDR--FTGQ--CRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFP 329
Query: 457 GSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNE 516
+ CLC G+TG RC LCP G G C+
Sbjct: 330 ANGACLCEHGFTGDRCT------------------------DRLCPDGFYGLSCQ----- 360
Query: 517 CASAPCL----NHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSP-------CANGGQ 565
APC + CH +NG +C CLPG++G C E + P C +GG
Sbjct: 361 ---APCTCDREHSLSCHP-MNG-ECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGV 415
Query: 566 CQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCE 625
CQ G C+C PG+ GP C + L P G +C + C C +
Sbjct: 416 CQATSGL--CQCAPGYTGPHCAS-----LCPPDTYGVNC-----SARCSCENAIA----- 458
Query: 626 VPLCAPNLCQPKQICKDQKDKANCL--CPDGSPGCAPPEDNCTC-HHGHC--QRSSCVCD 680
C+P + +CK+ + NC CP G+ G + +C C H C Q +C C
Sbjct: 459 ---CSP--IDGECVCKEGWQRGNCSVPCPPGTWGFS-CNASCQCAHEAVCSPQTGACTCT 512
Query: 681 VGWTGPECE-----AELG-GCIS-APCAHGGTCYPQPSGYNC-----------TCPTGYT 722
GW G C+ + G GC S C H C P C +CP G
Sbjct: 513 PGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGWMGARCHLSCPEGLW 572
Query: 723 GPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTD------YCVSAPC 776
G CS T C NGG+C P G C C P GP CQ S CV C
Sbjct: 573 GVNCSNTCT------CKNGGTCLPENGN--CVCAPGFRGPSCQRSCQPGRYGKRCVPCKC 624
Query: 777 FNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRP-----SCADS-PCRNRATCQDSPQGPRC 830
N C P +C C G+ GP C P +CA + C + TC PQ C
Sbjct: 625 ANHSFC--HPSNGTCYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHHGGTCH--PQDGSC 680
Query: 831 LCPTGYTGGSC------QTLMDLCAQKPC---PRNSHCLQTGPSFHCLCLQGWTGPLCNL 881
+CP G+TG C T C+Q PC P +TG C+C G +G C +
Sbjct: 681 ICPLGWTGHHCLEGCPLGTFGANCSQ-PCQCGPGEKCHPETGA---CVCPPGHSGAPCRI 736
Score = 227 bits (579), Expect = 8e-59
Identities = 201/685 (29%), Positives = 259/685 (37%), Gaps = 138/685 (20%)
Query: 613 CLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHC 672
C C G+ G C CAP + P Q DK C C + S C P C+C G
Sbjct: 120 CQCVPGWRGDDCSSE-CAPGMWGP------QCDKP-CSCGNNS-SCDPKSGVCSCPSG-L 169
Query: 673 QRSSCV--CDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEM 730
Q +C+ C G+ GP C+ C HG C PQ C CP TGP+C
Sbjct: 170 QPPNCLQPCTPGYYGPACQ------FRCQC-HGAPCDPQTGA--CFCPAERTGPSCDVSC 220
Query: 731 TACHSG-------PCLNGG-------SCNPSPG--GYYCT--CPPSHTGPQCQTSTDYCV 772
+ SG C NGG SC+ PG G C+ CP GP C
Sbjct: 221 SQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQE----- 275
Query: 773 SAPCFNGGTCVNRPGTFSCLCAMGFQGPRCE-----GKLRPSCADS-PCRNRATCQDSPQ 826
C NGG C G C CA G+ G RC G+ CA++ C A C P
Sbjct: 276 -CRCHNGGLCDRFTG--QCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARC--FPA 330
Query: 827 GPRCLCPTGYTGGSCQTLM------DLCAQKPCPRN-SHCLQTGP-SFHCLCLQGWTGPL 878
CLC G+TG C + L Q PC + H L P + C CL GW G
Sbjct: 331 NGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLH 390
Query: 879 CNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNP----- 933
CN SC + G LC +GG+C S C C PG+ G C P
Sbjct: 391 CN---ESCPQDTHGPGCQEHCLCLHGGVC--QATSGLCQCAPGYTGPHCASLCPPDTYGV 445
Query: 934 -CESR-PCQNGATCMAQPSGYLCQCAPGYDGQNCSKELD------ACQSQ-PCHNHGTCT 984
C +R C+N C P C C G+ NCS +C + C + C+
Sbjct: 446 NCSARCSCENAIAC--SPIDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCS 503
Query: 985 PKPGGFHCACPPGFVGLRCE-----GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT 1039
P+ G C C PG+ G C+ G E C + C + CQC G
Sbjct: 504 PQTGA--CTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGR--CQCQAGWM 559
Query: 1040 GQWCEVE-------IDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPS-- 1090
G C + ++ ++ C +GGTC G+ C C GF GP+C
Sbjct: 560 GARCHLSCPEGLWGVNCSNTCTCKNGGTCLPENGN-----CVCAPGFRGPSCQRSCQPGR 614
Query: 1091 ----CGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAP----KGCGPPSPCLY 1142
C C + C PS C CL+G+ GPDC P P + C C +
Sbjct: 615 YGKRCVPCKCANHSFCHPSNGT-----CYCLAGWTGPDCSQPCPPGHWGENCAQTCQCHH 669
Query: 1143 NGSCSETTG-----LGGPGFRC--SCPHSSPGPRCQKPGAKG----CEGRSGDGACDAGC 1191
G+C G LG G C CP + G C +P G C +G C G
Sbjct: 670 GGTCHPQDGSCICPLGWTGHHCLEGCPLGTFGANCSQPCQCGPGEKCHPETGACVCPPGH 729
Query: 1192 SGPGGNWDGGDCSLGVPDPWKGCPS 1216
S G C +G+ +P+ P+
Sbjct: 730 S-------GAPCRIGIQEPFTVMPT 747
Score = 221 bits (562), Expect = 7e-57
Identities = 207/720 (28%), Positives = 264/720 (36%), Gaps = 182/720 (25%)
Query: 341 CVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQP 400
C CV GW G DDC S C PG G C +P
Sbjct: 120 CQCVPGWRG-------DDC------------------SSECAPGMWGPQC-------DKP 147
Query: 401 CHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCE-----HGGSCLNT 455
C S +P +G +C C G P C L C GP+ C+ HG C
Sbjct: 148 CSCGNNSSCDPKSG--VCSCPSGLQPPNC---LQPCTPGYYGPA-CQFRCQCHGAPC--D 199
Query: 456 PGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFH-----CLCPPGLEGQLC 510
P + C CP TG C+ ++ S P + F C CPPG G +C
Sbjct: 200 PQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPPGWMGTIC 259
Query: 511 EVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQP 570
+ C GF G C + ECR C NGG C
Sbjct: 260 SLP-------------------------CPEGFHGPNCSQ---ECR---CHNGGLCDRFT 288
Query: 571 GAFHCKCLPGFEGPRCQTEV------DECLSD-PCPVGASCLDLPGAFFCLCPSGFTGQL 623
G C+C PG+ G RC+ E +C C A C GA CLC GFTG
Sbjct: 289 G--QCRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGA--CLCEHGFTGDR 344
Query: 624 CEVPLC----------APNLCQPKQI--CKDQKDKANCL-----------CPDGS--PGC 658
C LC AP C + C + +CL CP + PGC
Sbjct: 345 CTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGC 404
Query: 659 APPEDNCTCHHGH-CQRSS--CVCDVGWTGPECEA-----ELGGCISAPCAHGGTCYPQP 710
+++C C HG CQ +S C C G+TGP C + G SA C+ P
Sbjct: 405 ---QEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSP 461
Query: 711 SGYNCTCPTGYTGPTCSEEMT------ACHSG-PCLNGGSCNPSPGGYYCTCPPSHTGPQ 763
C C G+ CS +C++ C + C+P G CTC P G
Sbjct: 462 IDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSPQTGA--CTCTPGWHGAH 519
Query: 764 CQTST------DYCVS-APCFNGGTCVNRPGTFSCLCAMGFQGPRC-----EGKLRPSCA 811
CQ + C S C + C P C C G+ G RC EG +C+
Sbjct: 520 CQLPCPKGQFGEGCASRCDCDHSDGC--DPVHGRCQCQAGWMGARCHLSCPEGLWGVNCS 577
Query: 812 DS-PCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMD------LCAQKPCPRNSHCLQTGP 864
++ C+N TC P+ C+C G+ G SCQ C C +S C +
Sbjct: 578 NTCTCKNGGTCL--PENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPSNG 635
Query: 865 SFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQG 924
+ C CL GWTGP C+ P C + + CH+GG C S C CP G+ G
Sbjct: 636 T--CYCLAGWTGPDCSQP---CPPGHWGENCAQTCQCHHGGTCHPQDGS--CICPLGWTG 688
Query: 925 SLCQDHVNPCESRPCQN-GATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTC 983
C E P GA C +QP CQC P G+ C E AC P H+ C
Sbjct: 689 HHC------LEGCPLGTFGANC-SQP----CQCGP---GEKCHPETGACVCPPGHSGAPC 734
Score = 219 bits (558), Expect = 2e-56
Identities = 205/707 (28%), Positives = 266/707 (37%), Gaps = 132/707 (18%)
Query: 14 LLLCVSVVRPRGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQ-------FPD 66
L C RG + C +G C++ CQC PG+ G+ C +
Sbjct: 88 LQCCHGFYESRGFCVPLCAQECVHG-RCVA----PNQCQCVPGWRGDDCSSECAPGMWGP 142
Query: 67 PCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTP-SFLCTCLPGFTGERCQAKLE---DPC 122
C C N SC G+ S PS L P + L C PG+ G CQ + + PC
Sbjct: 143 QCDKPCSCGNNSSCDP----KSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPC 198
Query: 123 PPSFCSKRGRCHIQASGR-PQC--SCMPGWTGEQCQLRDFCSANPCVNGGVCLATYPQIQ 179
P + G C A P C SC G +G C S + C NGGV PQ
Sbjct: 199 DP----QTGACFCPAERTGPSCDVSCSQGTSGFFCP-----STHSCQNGGVFQT--PQGS 247
Query: 180 CHCPPGFEGHACERDVNECFQDPGPCPKGTSCHN----TLGSFQCLCPVGQEGPRCELRA 235
C CPPG+ G C E F P C + CHN + QC C G G RC
Sbjct: 248 CSCPPGWMGTICSLPCPEGFHGPN-CSQECRCHNGGLCDRFTGQCRCAPGYTGDRCREEC 306
Query: 236 GPCPPRGCSNGGTCQLMPEKDS--TFHLCLCPPGFIGPDC--EVNPDNCVSHQCQNGGTC 291
P G TC P+ CLC GF G C + PD CQ TC
Sbjct: 307 -PVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLSCQAPCTC 365
Query: 292 --QDGLDTYT----CLCPETWTGWDCSEDVDECETQGP---PHCR--NGGTCQNSAGSFH 340
+ L + C C W G C+E + +T GP HC +GG CQ ++G
Sbjct: 366 DREHSLSCHPMNGECSCLPGWAGLHCNESCPQ-DTHGPGCQEHCLCLHGGVCQATSGL-- 422
Query: 341 CVCVSGWGGTSCEENLD-DCIAATCAPGSTCIDRV-----------------GSFSCLCP 382
C C G+ G C D C+ +C + + G+ S CP
Sbjct: 423 CQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCP 482
Query: 383 PGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQG 442
PG G C+ S C +A CS P TG+ C C PG+ G C C Q G
Sbjct: 483 PGTWGFSCNA-----SCQCAHEAVCS--PQTGA--CTCTPGWHGAHCQLP---CPKGQFG 530
Query: 443 PS-----PCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECL-------SQPCHPGSTC 490
C+H C P C C G+ G+RC E L + C G TC
Sbjct: 531 EGCASRCDCDHSDGC--DPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTC 588
Query: 491 LDLLATFHCLCPPGLEGQLCEVETN------ECASAPCLNHADCHDLLNGFQCICLPGFS 544
L +C+C PG G C+ C C NH+ CH NG C CL G++
Sbjct: 589 LP--ENGNCVCAPGFRGPSCQRSCQPGRYGKRCVPCKCANHSFCHPS-NG-TCYCLAGWT 644
Query: 545 GTRCEEDI------DEC-RSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDEC---- 593
G C + + C ++ C +GG C Q G+ C C G+ G C ++ C
Sbjct: 645 GPDCSQPCPPGHWGENCAQTCQCHHGGTCHPQDGS--CICPLGWTGHHC---LEGCPLGT 699
Query: 594 ----LSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQP 636
S PC G P C+CP G +G C + + P P
Sbjct: 700 FGANCSQPCQCGPGEKCHPETGACVCPPGHSGAPCRIGIQEPFTVMP 746
Score = 186 bits (473), Expect = 2e-46
Identities = 173/647 (26%), Positives = 216/647 (33%), Gaps = 151/647 (23%)
Query: 720 GYTGPTCSEEMTACHSGPCLNGGSCNPSPG--GYYCT--CPPSHTGPQCQTSTDYCVSAP 775
G+ P C++E C G C+ C PG G C+ C P GPQC
Sbjct: 99 GFCVPLCAQE---CVHGRCVAPNQCQCVPGWRGDDCSSECAPGMWGPQCDKPCS------ 149
Query: 776 CFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPR---CLC 832
C N +C + G C C G Q P C P C+ R C +P P+ C C
Sbjct: 150 CGNNSSCDPKSGV--CSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCDPQTGACFC 207
Query: 833 PTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALS 892
P +TGPS C QG +G C S
Sbjct: 208 PAE-------------------------RTGPSCDVSCSQGTSGFFCPSTHS-------- 234
Query: 893 QGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQ-------DHVNPCESRPCQNGATC 945
C NGG V P C CPPG+ G++C N + C NG C
Sbjct: 235 --------CQNGG--VFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLC 284
Query: 946 MAQPSGYLCQCAPGYDGQNCSKEL-------DACQSQPCHNHGTCTPKPGGFHCA----- 993
C+CAPGY G C +E D ++ C C P G C
Sbjct: 285 DRFTGQ--CRCAPGYTGDRCREECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGFTG 342
Query: 994 -------CPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVE 1046
CP GF GL C+ C + +CH + C CLPG G C
Sbjct: 343 DRCTDRLCPDGFYGLSCQAPCT------CDREHSLSCHPMNGE--CSCLPGWAGLHCNES 394
Query: 1047 IDPCHSQP-------CFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAP------SCGF 1093
P C HGG C+AT+G +C C G+ GP C+ P +C
Sbjct: 395 CPQDTHGPGCQEHCLCLHGGVCQATSG-----LCQCAPGYTGPHCASLCPPDTYGVNCSA 449
Query: 1094 H-HCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPK----GCGPPSPCLYNGSCSE 1148
C + C P C C G+ +C P P C C + CS
Sbjct: 450 RCSCENAIACSP-----IDGECVCKEGWQRGNCSVPCPPGTWGFSCNASCQCAHEAVCSP 504
Query: 1149 TTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDA----GCSGPGGN------W 1198
TG C+C G CQ P KG G CD GC G W
Sbjct: 505 QTGA------CTCTPGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQAGW 558
Query: 1199 DGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECL--FDGYDCETPPACTPA-Y 1255
G C L P+ G + C G C P+ + C F G C+ +C P Y
Sbjct: 559 MGARCHLSCPEGLWGVNCSNTCTCK-NGGTCLPENGNCVCAPGFRGPSCQR--SCQPGRY 615
Query: 1256 DQYCHDHFHNGH--CEKGCNTAEC--GWDGGDCRPEDGDPEWGPSLA 1298
+ C H C T C GW G DC WG + A
Sbjct: 616 GKRCVPCKCANHSFCHPSNGTCYCLAGWTGPDCSQPCPPGHWGENCA 662
>gi|148886654 polydom [Homo sapiens]
Length = 3571
Score = 237 bits (604), Expect = 1e-61
Identities = 149/420 (35%), Positives = 192/420 (45%), Gaps = 76/420 (18%)
Query: 289 GTCQDGLDTYTC-LCPE-TWTGWDCSEDVDECETQGPPHCRNG---------------GT 331
G+ QD C LCP +T + S ++ +C+ Q C+ G GT
Sbjct: 1021 GSYQDEEGQLECKLCPSGMYTEYIHSRNISDCKAQ----CKQGTYSYSGLETCESCPLGT 1076
Query: 332 CQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPG---RTGL 388
Q GS C+ SC EN +T G+ I G CP G R+GL
Sbjct: 1077 YQPKFGSRSCL--------SCPEN-----TSTVKRGAVNISACG---VPCPEGKFSRSGL 1120
Query: 389 L-CHLEDMCLSQPCHGDAQC------STNPLTGS-----------TLCLCQPGYSGPTC- 429
+ CH QP G A C T P GS T + P
Sbjct: 1121 MPCHPCPRDYYQPNAGKAFCLACPFYGTTPFAGSRSITECSSFSSTFSAAEESVVPPASL 1180
Query: 430 ----------HQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNEC 479
Q EC +PC + G+C + CLCP GYTG +CE D +EC
Sbjct: 1181 GHIKKRHEISSQVFHECFF-----NPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDEC 1235
Query: 480 LSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCIC 539
PC C DL+ F C CP G GQ CE NEC+S+PCLN C D + G++C C
Sbjct: 1236 SPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTC 1295
Query: 540 LPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCP 599
+ GF G CE +++EC+S+PC N C+DQ G F CKC PGF G RC VDECLS PC
Sbjct: 1296 VKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCK 1355
Query: 600 VGASCLDLPGAFFCLCPSGFTGQLCEVPL--CAPNLCQPKQICKDQKDKANCLCPDGSPG 657
GA+C D +F CLC +GFTG CE+ + C N C+ + C D+ + +C C G G
Sbjct: 1356 NGATCKDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSG 1415
Score = 234 bits (597), Expect = 6e-61
Identities = 153/474 (32%), Positives = 196/474 (41%), Gaps = 88/474 (18%)
Query: 199 FQDPGPCPKGTSCHNTLGSFQCLCPVGQ----EGPRCELRAGPCPPRGCSNGGTCQLMPE 254
F PG +G C N CP+G E CE C G +
Sbjct: 987 FCRPGSVLRGRMCVN--------CPLGTYYNLEHFTCE---------SCRIGS----YQD 1025
Query: 255 KDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTY---------------T 299
++ LCP G + QC+ G GL+T +
Sbjct: 1026 EEGQLECKLCPSGMYTEYIHSRNISDCKAQCKQGTYSYSGLETCESCPLGTYQPKFGSRS 1085
Query: 300 CL-CPETWT------------GWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSG 346
CL CPE + G C E P H Q +AG C+
Sbjct: 1086 CLSCPENTSTVKRGAVNISACGVPCPEGKFSRSGLMPCHPCPRDYYQPNAGKAFCLACPF 1145
Query: 347 WGGTSCEENLDDCIAATCAPGSTCIDRVGSFSC--------LCPPGRTGLLCHLEDM--- 395
+G T GS I SFS + PP G + ++
Sbjct: 1146 YGTTPFA-------------GSRSITECSSFSSTFSAAEESVVPPASLGHIKKRHEISSQ 1192
Query: 396 ----CLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGS 451
C PCH C L +CLC GY+G C D+DEC P PC + G
Sbjct: 1193 VFHECFFNPCHNSGTCQQ--LGRGYVCLCPLGYTGLKCETDIDEC-----SPLPCLNNGV 1245
Query: 452 CLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCE 511
C + G F C CP GYTG RCE + NEC S PC C+D +A + C C G G CE
Sbjct: 1246 CKDLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCE 1305
Query: 512 VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPG 571
E NEC S PCLN+A C D + GF C C PGF GTRC +++DEC S PC NG C+D
Sbjct: 1306 TEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGAN 1365
Query: 572 AFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCE 625
+F C C GF G C+ ++EC S+PC A+C+D ++ C C GF+G+ CE
Sbjct: 1366 SFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCE 1419
Score = 206 bits (525), Expect = 1e-52
Identities = 130/429 (30%), Positives = 185/429 (43%), Gaps = 52/429 (12%)
Query: 177 QIQCH-CPPG-FEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELR 234
Q++C CP G + + R++++C C +GT ++ L + + CP+G P+ R
Sbjct: 1029 QLECKLCPSGMYTEYIHSRNISDC---KAQCKQGTYSYSGLETCES-CPLGTYQPKFGSR 1084
Query: 235 AGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVS-------HQCQN 287
+ C PE ST G C P+ S H C
Sbjct: 1085 S-------------CLSCPENTSTVKRGAVNISACGVPC---PEGKFSRSGLMPCHPCPR 1128
Query: 288 GGTCQDGLDTYTCLCP-ETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSG 346
+ + CP T + S + EC + SA V +
Sbjct: 1129 DYYQPNAGKAFCLACPFYGTTPFAGSRSITECSSFSSTF---------SAAEESVVPPAS 1179
Query: 347 WGGTSCEENLD-----DCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DMCLSQP 400
G + +C C TC + CLCP G TGL C + D C P
Sbjct: 1180 LGHIKKRHEISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLP 1239
Query: 401 CHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFN 460
C + C L G +C C GY+G C ++++EC SPC + G C++ +
Sbjct: 1240 CLNNGVCKD--LVGEFICECPSGYTGQRCEENINEC-----SSSPCLNKGICVDGVAGYR 1292
Query: 461 CLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASA 520
C C G+ G CE + NEC S PC + C D + F C CPPG G C +EC S
Sbjct: 1293 CTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQ 1352
Query: 521 PCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPG 580
PC N A C D N F+C+C GF+G+ CE +I+EC+S+PC N C D+ ++ CKC PG
Sbjct: 1353 PCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPG 1412
Query: 581 FEGPRCQTE 589
F G RC+TE
Sbjct: 1413 FSGKRCETE 1421
Score = 203 bits (516), Expect = 2e-51
Identities = 96/247 (38%), Positives = 123/247 (49%), Gaps = 16/247 (6%)
Query: 848 CAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLC 907
C PC + C Q G + CLC G+TG C + C C N G+C
Sbjct: 1197 CFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLP----------CLNNGVC 1246
Query: 908 VDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSK 967
D + C CP G+ G C++++N C S PC N C+ +GY C C G+ G +C
Sbjct: 1247 KDLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCET 1306
Query: 968 ELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLA 1027
E++ CQS PC N+ C + GGF C CPPGF+G RC +VDECL QPC A C A
Sbjct: 1307 EVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPC--KNGATCKDGA 1364
Query: 1028 NAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHR 1087
N+F C C G TG CE+ I+ C S PC + TC S + C C GF G C
Sbjct: 1365 NSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNS---YSCKCQPGFSGKRC-ET 1420
Query: 1088 APSCGFH 1094
S GF+
Sbjct: 1421 EQSTGFN 1427
Score = 199 bits (507), Expect = 2e-50
Identities = 108/337 (32%), Positives = 147/337 (43%), Gaps = 38/337 (11%)
Query: 592 ECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPL--CAPNLCQPKQICKDQKDKANC 649
EC +PC +C L + CLCP G+TG CE + C+P C +CKD + C
Sbjct: 1196 ECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFIC 1255
Query: 650 LCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQ 709
CP G +TG CE + C S+PC + G C
Sbjct: 1256 ECPSG----------------------------YTGQRCEENINECSSSPCLNKGICVDG 1287
Query: 710 PSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTD 769
+GY CTC G+ G C E+ C S PCLN C GG+ C CPP G +C + D
Sbjct: 1288 VAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVD 1347
Query: 770 YCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPR 829
C+S PC NG TC + +F CLCA GF G CE + C +PCRN+ATC D
Sbjct: 1348 ECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCELNIN-ECQSNPCRNQATCVDELNSYS 1406
Query: 830 CLCPTGYTGGSCQTLMDLCAQKPCPRN---SHCLQTG--PSFHCLCLQGWTGPLCNLPLS 884
C C G++G C+T + + + G PS H L W ++
Sbjct: 1407 CKCQPGFSGKRCETEQSTGFNLDFEVSGIYGYVMLDGMLPSLHALTCTFWMKSSDDMNYG 1466
Query: 885 SCQKAALSQGIDVSSLC--HNGGLCVDSGPSYFCHCP 919
+ A+ G D + L +NG + +G +CP
Sbjct: 1467 TPISYAVDNGSDNTLLLTDYNGWVLYVNGREKITNCP 1503
Score = 198 bits (504), Expect = 4e-50
Identities = 90/242 (37%), Positives = 120/242 (49%), Gaps = 11/242 (4%)
Query: 727 SEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRP 786
S+ C PC N G+C GY C CP +TG +C+T D C PC N G C +
Sbjct: 1191 SQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLV 1250
Query: 787 GTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMD 846
G F C C G+ G RCE + C+ SPC N+ C D G RC C G+ G C+T ++
Sbjct: 1251 GEFICECPSGYTGQRCEENIN-ECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVN 1309
Query: 847 LCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGL 906
C PC N+ C F C C G+ G C + C +S C NG
Sbjct: 1310 ECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDEC----------LSQPCKNGAT 1359
Query: 907 CVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCS 966
C D S+ C C GF GS C+ ++N C+S PC+N ATC+ + + Y C+C PG+ G+ C
Sbjct: 1360 CKDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCE 1419
Query: 967 KE 968
E
Sbjct: 1420 TE 1421
Score = 189 bits (480), Expect = 2e-47
Identities = 88/234 (37%), Positives = 120/234 (51%), Gaps = 9/234 (3%)
Query: 160 CSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQ 219
C NPC N G C C CP G+ G CE D++EC P PC C + +G F
Sbjct: 1197 CFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDEC--SPLPCLNNGVCKDLVGEFI 1254
Query: 220 CLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDN 279
C CP G G RCE C C N G C + C C GF+G CE +
Sbjct: 1255 CECPSGYTGQRCEENINECSSSPCLNKGICV----DGVAGYRCTCVKGFVGLHCETEVNE 1310
Query: 280 CVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSF 339
C S+ C N C+D + + C CP + G C ++VDEC +Q C+NG TC++ A SF
Sbjct: 1311 CQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQP---CKNGATCKDGANSF 1367
Query: 340 HCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE 393
C+C +G+ G+ CE N+++C + C +TC+D + S+SC C PG +G C E
Sbjct: 1368 RCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETE 1421
Score = 184 bits (467), Expect = 8e-46
Identities = 85/236 (36%), Positives = 123/236 (52%), Gaps = 15/236 (6%)
Query: 243 CSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLC 302
C N GTCQ + ++CLCP G+ G CE + D C C N G C+D + + C C
Sbjct: 1202 CHNSGTCQQLGRG----YVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICEC 1257
Query: 303 PETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAA 362
P +TG C E+++EC + C N G C + + C CV G+ G CE +++C +
Sbjct: 1258 PSGYTGQRCEENINECSSSP---CLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSN 1314
Query: 363 TCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DMCLSQPCHGDAQCSTNPLTGSTLCLCQ 421
C + C D+VG F C CPPG G C D CLSQPC A C S CLC
Sbjct: 1315 PCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDG--ANSFRCLCA 1372
Query: 422 PGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHN 477
G++G C +++EC +PC + +C++ S++C C PG++G RCE + +
Sbjct: 1373 AGFTGSHCELNINECQS-----NPCRNQATCVDELNSYSCKCQPGFSGKRCETEQS 1423
Score = 181 bits (458), Expect = 8e-45
Identities = 122/414 (29%), Positives = 156/414 (37%), Gaps = 55/414 (13%)
Query: 744 CNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSC-LCAMGFQGPRC 802
C P G Y S C+ A C G + G +C C +G P+
Sbjct: 1032 CKLCPSGMYTEYIHSRNISDCK--------AQCKQG--TYSYSGLETCESCPLGTYQPKF 1081
Query: 803 EGKLRPSCADSPCR-NRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQ 861
+ SC ++ R S G C P G S L PCPR+ +
Sbjct: 1082 GSRSCLSCPENTSTVKRGAVNISACGVPC--PEGKFSRS-----GLMPCHPCPRDYYQPN 1134
Query: 862 TGPSFHCLCLQGWTGPLCNL-------PLSSCQKAALSQGIDVSSL-------------- 900
G +F C T P SS AA + +SL
Sbjct: 1135 AGKAFCLACPFYGTTPFAGSRSITECSSFSSTFSAAEESVVPPASLGHIKKRHEISSQVF 1194
Query: 901 -------CHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYL 953
CHN G C G Y C CP G+ G C+ ++ C PC N C ++
Sbjct: 1195 HECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFI 1254
Query: 954 CQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQ 1013
C+C GY GQ C + ++ C S PC N G C G+ C C GFVGL CE +V+EC
Sbjct: 1255 CECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSN 1314
Query: 1014 PCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFIC 1073
PC A C F C+C PG G C +D C SQPC +G TC+ A S F C
Sbjct: 1315 PC--LNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANS---FRC 1369
Query: 1074 HCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLT 1127
C GF G C C + C + C+ C C G+ G C T
Sbjct: 1370 LCAAGFTGSHCELNINECQSNPCRNQATCVDELN---SYSCKCQPGFSGKRCET 1420
Score = 171 bits (433), Expect = 7e-42
Identities = 85/229 (37%), Positives = 113/229 (49%), Gaps = 13/229 (5%)
Query: 127 CSKRGRCHIQASGRPQ-CSCMPGWTGEQCQLR-DFCSANPCVNGGVCLATYPQIQCHCPP 184
C G C Q GR C C G+TG +C+ D CS PC+N GVC + C CP
Sbjct: 1202 CHNSGTC--QQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPS 1259
Query: 185 GFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCS 244
G+ G CE ++NEC PC C + + ++C C G G CE C C
Sbjct: 1260 GYTGQRCEENINEC--SSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCL 1317
Query: 245 NGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPE 304
N C E LC CPPGF+G C N D C+S C+NG TC+DG +++ CLC
Sbjct: 1318 NNAVC----EDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAA 1373
Query: 305 TWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCE 353
+TG C +++EC++ CRN TC + S+ C C G+ G CE
Sbjct: 1374 GFTGSHCELNINECQSN---PCRNQATCVDELNSYSCKCQPGFSGKRCE 1419
Score = 153 bits (386), Expect = 2e-36
Identities = 87/246 (35%), Positives = 116/246 (47%), Gaps = 26/246 (10%)
Query: 31 FPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLG 89
F PC N GTC L G C C G+ G C+ D C C N G C+ L+
Sbjct: 1198 FFNPCHNSGTCQQLGRGY-VCLCPLGYTGLKCETDIDECSPLP-CLNNGVCKDLVG---- 1251
Query: 90 LPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGW 149
F+C C G+TG+RC+ + + C S C +G C +G +C+C+ G+
Sbjct: 1252 ----------EFICECPSGYTGQRCEENINE-CSSSPCLNKGICVDGVAGY-RCTCVKGF 1299
Query: 150 TGEQCQLR-DFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKG 208
G C+ + C +NPC+N VC C CPPGF G C ++V+EC PC G
Sbjct: 1300 VGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQ--PCKNG 1357
Query: 209 TSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGF 268
+C + SF+CLC G G CEL C C N TC + E +S + C C PGF
Sbjct: 1358 ATCKDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATC--VDELNS--YSCKCQPGF 1413
Query: 269 IGPDCE 274
G CE
Sbjct: 1414 SGKRCE 1419
Score = 126 bits (317), Expect = 2e-28
Identities = 72/206 (34%), Positives = 89/206 (43%), Gaps = 15/206 (7%)
Query: 966 SKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHS 1025
S+ C PCHN GTC G+ C CP G+ GL+CE D+DEC PC G C
Sbjct: 1191 SQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNG--VCKD 1248
Query: 1026 LANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCS 1085
L F C+C G+TGQ CE I+ C S PC + G C G+ C C KGF G C
Sbjct: 1249 LVGEFICECPSGYTGQRCEENINECSSSPCLNKGIC---VDGVAGYRCTCVKGFVGLHCE 1305
Query: 1086 HRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGS 1145
C + C + +C GF C C G+ G C C PC +
Sbjct: 1306 TEVNECQSNPCLNNAVC-EDQVGGF--LCKCPPGFLGTRC--GKNVDEC-LSQPCKNGAT 1359
Query: 1146 CSETTGLGGPGFRCSCPHSSPGPRCQ 1171
C + G FRC C G C+
Sbjct: 1360 CKD----GANSFRCLCAAGFTGSHCE 1381
Score = 114 bits (285), Expect = 1e-24
Identities = 75/248 (30%), Positives = 101/248 (40%), Gaps = 39/248 (15%)
Query: 1009 ECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSP 1068
EC PCH +GT C L + C C G+TG CE +ID C PC + G C+ G
Sbjct: 1196 ECFFNPCHNSGT--CQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGE- 1252
Query: 1069 LGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTP 1128
FIC CP G+ G C C C + G+C+ G+ RC C+ G+ G C T
Sbjct: 1253 --FICECPSGYTGQRCEENINECSSSPCLNKGICVDGVA-GY--RCTCVKGFVGLHCETE 1307
Query: 1129 PAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACD 1188
C +PCL N C + G GF C CP G RC G++ D
Sbjct: 1308 V--NEC-QSNPCLNNAVCEDQVG----GFLCKCPPGFLGTRC---------GKNVDECLS 1351
Query: 1189 AGCSGPGGNWDGGD-----CSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEECL--FD 1241
C DG + C+ G + S C L + Q +P + C+ +
Sbjct: 1352 QPCKNGATCKDGANSFRCLCAAGF--------TGSHCELNINECQSNPCRNQATCVDELN 1403
Query: 1242 GYDCETPP 1249
Y C+ P
Sbjct: 1404 SYSCKCQP 1411
Score = 93.6 bits (231), Expect = 2e-18
Identities = 65/214 (30%), Positives = 89/214 (41%), Gaps = 33/214 (15%)
Query: 16 LCVSVVRPRGLLCGS-----FPEPCANGGTCLSLSLGQGTCQCAPGFLGETCQ------F 64
+C+ + GL C + P PC N G C L +G+ C+C G+ G+ C+
Sbjct: 1216 VCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDL-VGEFICECPSGYTGQRCEENINECS 1274
Query: 65 PDPCQNAQLCQNG--GSCQALLPAPLGL---------PSSP-------SPLTPSFLCTCL 106
PC N +C +G G + +GL S+P FLC C
Sbjct: 1275 SSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCP 1334
Query: 107 PGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR-DFCSANPC 165
PGF G RC K D C C C A+ +C C G+TG C+L + C +NPC
Sbjct: 1335 PGFLGTRC-GKNVDECLSQPCKNGATCKDGANSF-RCLCAAGFTGSHCELNINECQSNPC 1392
Query: 166 VNGGVCLATYPQIQCHCPPGFEGHACERDVNECF 199
N C+ C C PGF G CE + + F
Sbjct: 1393 RNQATCVDELNSYSCKCQPGFSGKRCETEQSTGF 1426
Score = 82.8 bits (203), Expect = 3e-15
Identities = 54/147 (36%), Positives = 69/147 (46%), Gaps = 24/147 (16%)
Query: 666 TCHHGHCQ----RSSCVCDVGWTGPE-CEAELGGCISAPCAHGGTCYPQPSGYNCTCPTG 720
+C+ G+ RS C+ + WT P C A PC +GG C +P+ C+CP G
Sbjct: 3441 SCYSGYMLEGFLRSVCLENGTWTSPPICRA----VCRFPCQNGGICQ-RPNA--CSCPEG 3493
Query: 721 YTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGG 780
+ G C E + PCLNGG C Y C CPP TG +C T+ +PC NGG
Sbjct: 3494 WMGRLCEEPICIL---PCLNGGRC---VAPYQCDCPPGWTGSRCHTAV---CQSPCLNGG 3544
Query: 781 TCVNRPGTFSCLCAMGFQGPRCEGKLR 807
CV RP C C + G C K R
Sbjct: 3545 KCV-RPN--RCHCLSSWTGHNCSRKRR 3568
Score = 69.3 bits (168), Expect = 4e-11
Identities = 50/155 (32%), Positives = 64/155 (41%), Gaps = 39/155 (25%)
Query: 39 GTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLT 98
G S+ L GT +P C+FP CQNGG CQ P++
Sbjct: 3450 GFLRSVCLENGTWT-SPPICRAVCRFP--------CQNGGICQR--------PNA----- 3487
Query: 99 PSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRD 158
C+C G+ G C E+P C GRC QC C PGWTG +C
Sbjct: 3488 ----CSCPEGWMGRLC----EEPICILPCLNGGRCVAPY----QCDCPPGWTGSRCHTA- 3534
Query: 159 FCSANPCVNGGVCLATYPQIQCHCPPGFEGHACER 193
+PC+NGG C+ +CHC + GH C R
Sbjct: 3535 -VCQSPCLNGGKCVRPN---RCHCLSSWTGHNCSR 3565
Score = 67.4 bits (163), Expect = 1e-10
Identities = 78/297 (26%), Positives = 101/297 (34%), Gaps = 81/297 (27%)
Query: 692 LGGCISAPCAHGGT-CYPQPSGYNCTCPTGYTGPT---CSEE--------MTACHSGPCL 739
L G A C GT +P P CP + P SE+ C G L
Sbjct: 3331 LEGPSEAHCTENGTWSHPVPLCKPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFLL 3390
Query: 740 NGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPG--------TFSC 791
G TC P T Q + P + + R T+SC
Sbjct: 3391 QGHGI--------ITCNPDETWTQTSAKCEKISCGPPAHVENAIARGVHYQYGDMITYSC 3442
Query: 792 LCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQK 851
+ G EG LR C ++ SP R +C +
Sbjct: 3443 -----YSGYMLEGFLRSVCLENGTWT------SPPICRAVC-----------------RF 3474
Query: 852 PCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSG 911
PC C + C C +GW G LC P+ C NGG CV
Sbjct: 3475 PCQNGGICQRPNA---CSCPEGWMGRLCEEPICILP-------------CLNGGRCV--- 3515
Query: 912 PSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKE 968
Y C CPPG+ GS C H C+S PC NG C+ +P+ C C + G NCS++
Sbjct: 3516 APYQCDCPPGWTGSRC--HTAVCQS-PCLNGGKCV-RPN--RCHCLSSWTGHNCSRK 3566
Score = 63.9 bits (154), Expect = 1e-09
Identities = 39/104 (37%), Positives = 50/104 (48%), Gaps = 15/104 (14%)
Query: 483 PCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPG 542
PC G C A C CP G G+LCE PCLN C + +QC C PG
Sbjct: 3475 PCQNGGICQRPNA---CSCPEGWMGRLCE---EPICILPCLNGGRC---VAPYQCDCPPG 3525
Query: 543 FSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRC 586
++G+RC + + SPC NGG+C +P C CL + G C
Sbjct: 3526 WTGSRCHTAVCQ---SPCLNGGKCV-RPN--RCHCLSSWTGHNC 3563
Score = 62.0 bits (149), Expect = 6e-09
Identities = 48/149 (32%), Positives = 63/149 (42%), Gaps = 23/149 (15%)
Query: 281 VSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFH 340
+++ C +G + L + CL TWT S + + P C+NGG CQ
Sbjct: 3438 ITYSCYSGYMLEGFLRS-VCLENGTWT----SPPICRAVCRFP--CQNGGICQRPNA--- 3487
Query: 341 CVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQP 400
C C GW G CEE + CI C G C V + C CPPG TG CH +C S P
Sbjct: 3488 CSCPEGWMGRLCEEPI--CILP-CLNGGRC---VAPYQCDCPPGWTGSRCHTA-VCQS-P 3539
Query: 401 CHGDAQCSTNPLTGSTLCLCQPGYSGPTC 429
C +C C C ++G C
Sbjct: 3540 CLNGGKC-----VRPNRCHCLSSWTGHNC 3563
Score = 60.5 bits (145), Expect = 2e-08
Identities = 66/257 (25%), Positives = 86/257 (33%), Gaps = 60/257 (23%)
Query: 264 CPPGFIGPDC------EVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDE 317
CP F+ P+ E D VS +C+ G Q G TC ETWT +
Sbjct: 3357 CPVPFVIPENALLSEKEFYVDQNVSIKCREGFLLQ-GHGIITCNPDETWTQTSAKCEKIS 3415
Query: 318 CETQGPP-HCRNG---GTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDR 373
C GPP H N G C SG+ L+ + + C T
Sbjct: 3416 C---GPPAHVENAIARGVHYQYGDMITYSCYSGY-------MLEGFLRSVCLENGTWTS- 3464
Query: 374 VGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDL 433
P +C PC C C C G+ G C + +
Sbjct: 3465 ---------PPICRAVCRF-------PCQNGGICQR-----PNACSCPEGWMGRLCEEPI 3503
Query: 434 DECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDL 493
C++ PC +GG C+ + C CPPG+TGSRC H PC G C
Sbjct: 3504 --CIL------PCLNGGRCV---APYQCDCPPGWTGSRC---HTAVCQSPCLNGGKC--- 3546
Query: 494 LATFHCLCPPGLEGQLC 510
+ C C G C
Sbjct: 3547 VRPNRCHCLSSWTGHNC 3563
Score = 60.5 bits (145), Expect = 2e-08
Identities = 59/192 (30%), Positives = 72/192 (37%), Gaps = 43/192 (22%)
Query: 102 LCTCLPGFTGERCQAKLED-PC-PPSFCSK---RGRCHIQASGRPQCSCMPGWTGEQCQL 156
+ TC P T + AK E C PP+ RG H Q SC G+ E L
Sbjct: 3395 IITCNPDETWTQTSAKCEKISCGPPAHVENAIARG-VHYQYGDMITYSCYSGYMLEGF-L 3452
Query: 157 RDFCSAN---------------PCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQD 201
R C N PC NGG+C C CP G+ G CE + C
Sbjct: 3453 RSVCLENGTWTSPPICRAVCRFPCQNGGICQRPNA---CSCPEGWMGRLCEEPI--CIL- 3506
Query: 202 PGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHL 261
PC G C + +QC CP G G RC P C NGG C + P +
Sbjct: 3507 --PCLNGGRC---VAPYQCDCPPGWTGSRCHTAVCQSP---CLNGGKC-VRPNR------ 3551
Query: 262 CLCPPGFIGPDC 273
C C + G +C
Sbjct: 3552 CHCLSSWTGHNC 3563
Score = 58.2 bits (139), Expect = 8e-08
Identities = 39/123 (31%), Positives = 47/123 (38%), Gaps = 36/123 (29%)
Query: 34 PCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSS 93
PC NGG C C C G++G C+ P C C NGG C A
Sbjct: 3475 PCQNGGICQR----PNACSCPEGWMGRLCEEP-IC--ILPCLNGGRCVA----------- 3516
Query: 94 PSPLTPSFLCTCLPGFTGERCQ-AKLEDPC-PPSFCSKRGRCHIQASGRPQCSCMPGWTG 151
+ C C PG+TG RC A + PC C + RCH C+ WTG
Sbjct: 3517 ------PYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCH----------CLSSWTG 3560
Query: 152 EQC 154
C
Sbjct: 3561 HNC 3563
Score = 57.8 bits (138), Expect = 1e-07
Identities = 65/243 (26%), Positives = 85/243 (34%), Gaps = 73/243 (30%)
Query: 197 ECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCP-----PRGCSNG-GTCQ 250
+C G C GT G F+C+C G G + CP P G G +C
Sbjct: 286 DCCDRMGSCKCGTHT----GHFECICEKGYYGKGLQYECTACPSGTYKPEGSPGGISSCI 341
Query: 251 LMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWD 310
P+++ T PPG +P++CV C++G +G
Sbjct: 342 PCPDENHT-----SPPG------STSPEDCV---------CREGYRA---------SGQT 372
Query: 311 CSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTC 370
C ++ C PP NG QN +C + + C PG
Sbjct: 373 C--ELVHCPALKPP--ENGYFIQN----------------TCNNHFNAACGVRCHPG--- 409
Query: 371 IDRVGSFSCLCPPGRTGLLCHLEDMC-------LSQPCHGDAQCSTNPLTGSTLCL--CQ 421
D VGS LC P GL E C L QP HG CST + T CL C
Sbjct: 410 FDLVGSSIILCLP--NGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACD 467
Query: 422 PGY 424
GY
Sbjct: 468 EGY 470
Score = 56.6 bits (135), Expect = 2e-07
Identities = 41/104 (39%), Positives = 47/104 (45%), Gaps = 15/104 (14%)
Query: 521 PCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPG 580
PC N C C C G+ G CEE I C PC NGG+C + C C PG
Sbjct: 3475 PCQNGGICQ---RPNACSCPEGWMGRLCEEPI--C-ILPCLNGGRCV---APYQCDCPPG 3525
Query: 581 FEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLC 624
+ G RC T V C S PC G C+ P C C S +TG C
Sbjct: 3526 WTGSRCHTAV--CQS-PCLNGGKCV-RPNR--CHCLSSWTGHNC 3563
Score = 53.9 bits (128), Expect = 2e-06
Identities = 169/746 (22%), Positives = 229/746 (30%), Gaps = 153/746 (20%)
Query: 496 TFHCLCPPGLEGQ---LCEVETNECASAPCLNHADC-------HDLLNGFQCI------- 538
TFHC L G C+ + N A P +C H NGF I
Sbjct: 2914 TFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHGFPNGFSFIHGGHIQY 2973
Query: 539 -CLPGF-----SGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKC-LPGFE-GPRCQTEV 590
C PG+ S RC +NG P C+C P E G T+
Sbjct: 2974 QCFPGYKLHGNSSRRC-----------LSNGSWSGSSPSCLPCRCSTPVIEYGTVNGTDF 3022
Query: 591 D--ECLSDPCPVGASCLDLPGAFFCLCPSGFTGQL--CEVPLCAPNLCQPKQICKDQKD- 645
D + C G L L C ++ CE C P +
Sbjct: 3023 DCGKAARIQCFKGFKLLGL-SEITCEADGQWSSGFPHCEHTSCGSLPMIPNAFISETSSW 3081
Query: 646 KANCLCPDGSPGCAPPEDNCTCHHGHCQRSS----CVCDVGWTGPECEAELGGCISAPCA 701
K N + +C G+ + S C W+ P E C S P
Sbjct: 3082 KENVI-------------TYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPSV 3128
Query: 702 HG----GTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPP 757
G + S C GYT T ++ T C G P +C P
Sbjct: 3129 ANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFT------CQKDGRWFPER----ISCSP 3178
Query: 758 SHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGP-----RCEGKLRPSCAD 812
P + T V F+ VNR + SC F+G + +G P +D
Sbjct: 3179 KKC-PLPENITHILVHGDDFS----VNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFSD 3233
Query: 813 SPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQ 872
C + +C P+ P G+ GS T + P + L+ C +
Sbjct: 3234 ESC-SPVSC-GKPESPE----HGFVVGSKYTFESTIIYQCEP--GYELEGNRERVCQENR 3285
Query: 873 GWTGPL-------CNLPLSSCQKAA----LSQGIDVSSLCHNGGLCVDSGPSYFCHCPPG 921
W+G + C PL A + G +V C+ G GPS HC
Sbjct: 3286 QWSGGVAICKETRCETPLEFLNGKADIENRTTGPNVVYSCNRGYSL--EGPSE-AHCT-- 3340
Query: 922 FQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHG 981
+ V C+ PC P L Y QN S + H
Sbjct: 3341 -ENGTWSHPVPLCKPNPCP---VPFVIPENALLSEKEFYVDQNVSIKCREGFLLQGHGII 3396
Query: 982 TCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCH----PTGTAACHS---LANAFYCQC 1034
TC P + + V+ + + H T +C+S L C
Sbjct: 3397 TCNPDETWTQTSAKCEKISCGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVC 3456
Query: 1035 LPGHTGQWCEVEIDPCHSQ---PCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSC 1091
L G W I C + PC +GG C+ C CP+G+ G C P C
Sbjct: 3457 L--ENGTWTSPPI--CRAVCRFPCQNGGICQRPNA------CSCPEGWMGRLCEE--PIC 3504
Query: 1092 GFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTG 1151
C +GG C+ P +C C G+ G C T SPCL G C
Sbjct: 3505 -ILPCLNGGRCVA------PYQCDCPPGWTGSRCHTAVC------QSPCLNGGKCVRPN- 3550
Query: 1152 LGGPGFRCSCPHSSPGPRCQKPGAKG 1177
RC C S G C + G
Sbjct: 3551 ------RCHCLSSWTGHNCSRKRRTG 3570
Score = 53.1 bits (126), Expect = 3e-06
Identities = 39/109 (35%), Positives = 45/109 (41%), Gaps = 19/109 (17%)
Query: 204 PCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCL 263
PC G C C CP G G CE P C NGG C + P + C
Sbjct: 3475 PCQNGGICQRPNA---CSCPEGWMGRLCEEPICILP---CLNGGRC-VAP------YQCD 3521
Query: 264 CPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCS 312
CPPG+ G C C S C NGG C + C C +WTG +CS
Sbjct: 3522 CPPGWTGSRCHTAV--CQS-PCLNGGKC---VRPNRCHCLSSWTGHNCS 3564
Score = 48.5 bits (114), Expect = 6e-05
Identities = 63/260 (24%), Positives = 84/260 (32%), Gaps = 68/260 (26%)
Query: 287 NGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSG 346
+G QD + + LC E G DC + + C+ C G F C+C G
Sbjct: 266 SGSFIQDDMVHCSYLCDE---GKDCCDRMGSCK------------CGTHTGHFECICEKG 310
Query: 347 WGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQ 406
+ G + C + T P + G SC+ PC +
Sbjct: 311 YYGKGLQYECTACPSGTYKPEGS---PGGISSCI-------------------PCPDENH 348
Query: 407 CSTNPLTGSTLCLCQPGY--SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCP 464
S T C+C+ GY SG TC +L C P E+G NT
Sbjct: 349 TSPPGSTSPEDCVCREGYRASGQTC--ELVHC----PALKPPENGYFIQNT--------- 393
Query: 465 PGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLC-PPGL---EGQLCEVETNECASA 520
C N CHPG DL+ + LC P GL C V T
Sbjct: 394 -------CNNHFNAACGVRCHPG---FDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQ 443
Query: 521 PCLNHADCHDLLNGFQCICL 540
P H C ++ CL
Sbjct: 444 PKHGHISCSTREMLYKTTCL 463
Score = 45.1 bits (105), Expect = 7e-04
Identities = 73/285 (25%), Positives = 94/285 (32%), Gaps = 92/285 (32%)
Query: 513 ETNECASAPCLNHADCHDLLNGFQCICLPGF-----SGTRCEEDIDECRSSPCANGGQCQ 567
E N+ AS P H F+ + SG+ ++D+ C S C G C
Sbjct: 230 ELNDMASTPKEEHCYLLHSFEEFEALARRALHEDLPSGSFIQDDMVHC-SYLCDEGKDCC 288
Query: 568 DQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVP 627
D+ G+ CKC G G F C+C G+ G+ +
Sbjct: 289 DRMGS--CKC-----------------------GTHT----GHFECICEKGYYGKGLQYE 319
Query: 628 LCAPNLCQPKQICKDQKDKANCLCPDGSPG----CAP-PEDNCTCHHGHCQRSSCVCDVG 682
A C K P+GSPG C P P++N T G CVC G
Sbjct: 320 CTA---------CPSGTYK-----PEGSPGGISSCIPCPDENHTSPPGSTSPEDCVCREG 365
Query: 683 W--TGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTA-----CHS 735
+ +G CE H P +GY + TC+ A CH
Sbjct: 366 YRASGQTCE----------LVHCPALKPPENGY-------FIQNTCNNHFNAACGVRCHP 408
Query: 736 GPCLNGGS---CNP----SPGGYYC---TCP----PSHTGPQCQT 766
G L G S C P S YC TCP P H C T
Sbjct: 409 GFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCST 453
Score = 44.7 bits (104), Expect = 0.001
Identities = 37/117 (31%), Positives = 45/117 (38%), Gaps = 24/117 (20%)
Query: 671 HCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEM 730
HC S +CD G +C +G C C + C C GY G E
Sbjct: 276 HC---SYLCD---EGKDCCDRMGSC---------KCGTHTGHFECICEKGYYGKGLQYEC 320
Query: 731 TACHSGPCLNGGSCNPSPGGYYCTCP---PSHTGPQCQTSTDYCVSAPCF--NGGTC 782
TAC SG G SPGG P +HT P TS + CV + +G TC
Sbjct: 321 TACPSGTYKPEG----SPGGISSCIPCPDENHTSPPGSTSPEDCVCREGYRASGQTC 373
Score = 41.6 bits (96), Expect = 0.008
Identities = 27/84 (32%), Positives = 34/84 (40%), Gaps = 24/84 (28%)
Query: 34 PCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSS 93
PC NGG C++ C C PG+ G C CQ+ C NGG C
Sbjct: 3507 PCLNGGRCVA----PYQCDCPPGWTGSRCHTA-VCQSP--CLNGGKC------------- 3546
Query: 94 PSPLTPSFLCTCLPGFTGERCQAK 117
+ P+ C CL +TG C K
Sbjct: 3547 ---VRPN-RCHCLSSWTGHNCSRK 3566
Score = 40.8 bits (94), Expect = 0.013
Identities = 20/43 (46%), Positives = 24/43 (55%), Gaps = 5/43 (11%)
Query: 427 PTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTG 469
P+C D+DEC + S C SCLN GS+ C C P YTG
Sbjct: 1741 PSC-LDVDECAVG----SDCSEHASCLNVDGSYICSCVPPYTG 1778
Score = 38.1 bits (87), Expect = 0.087
Identities = 31/121 (25%), Positives = 44/121 (36%), Gaps = 16/121 (13%)
Query: 864 PSFHCLCLQGWTGPLCNLPLSSC-----------QKAALSQGIDVSSLCHNGGLCVDSGP 912
P +CL WT PL + SC G V+ C+NG +
Sbjct: 1668 PVQYCLNQGQWTQPLPHCERISCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDS- 1726
Query: 913 SYFCHCPPGFQG--SLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGY--DGQNCSKE 968
FC + G C D C A+C+ Y+C C P Y DG+NC++
Sbjct: 1727 RMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEP 1786
Query: 969 L 969
+
Sbjct: 1787 I 1787
Score = 36.2 bits (82), Expect = 0.33
Identities = 35/138 (25%), Positives = 49/138 (35%), Gaps = 23/138 (16%)
Query: 748 PGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCE---- 803
P G + H C D C GT G F C+C G+ G +
Sbjct: 265 PSGSFIQDDMVHCSYLCDEGKDCCDRMGSCKCGT---HTGHFECICEKGYYGKGLQYECT 321
Query: 804 ----GKLRP--------SCADSPCRNRATCQDSPQGPRCLCPTGY--TGGSCQTLMDLCA 849
G +P SC P N + S C+C GY +G +C+ L+ A
Sbjct: 322 ACPSGTYKPEGSPGGISSCIPCPDENHTSPPGSTSPEDCVCREGYRASGQTCE-LVHCPA 380
Query: 850 QKPCPRNSHCLQTGPSFH 867
KP P N + +Q + H
Sbjct: 381 LKP-PENGYFIQNTCNNH 397
Score = 35.8 bits (81), Expect = 0.43
Identities = 61/261 (23%), Positives = 81/261 (31%), Gaps = 65/261 (24%)
Query: 913 SYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDAC 972
SY C +G C D + C+ C + C C GY G+ E AC
Sbjct: 278 SYLCD-----EGKDCCDRMGSCK---------CGTHTGHFECICEKGYYGKGLQYECTAC 323
Query: 973 QSQPCHNHGTCTPK--PGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAF 1030
S GT P+ PGG + C+ PC + +
Sbjct: 324 PS------GTYKPEGSPGG-----------------ISSCI--PCPDENHTSPPGSTSPE 358
Query: 1031 YCQCLPGH--TGQWCEVEIDPCHSQP---CFHGGTCEATAGSPLGFICH----------- 1074
C C G+ +GQ CE+ P P F TC + G CH
Sbjct: 359 DCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSII 418
Query: 1075 --CPKG-FEGPTCSHRAPSC-GFHHCHHGGLCLPSPKPGFPPRC--ACLSGY--GGPDCL 1126
P G + G R +C HG + + + + C AC GY G D L
Sbjct: 419 LCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKL 478
Query: 1127 TPPAPKGCGPPSPCLYNGSCS 1147
T P P CS
Sbjct: 479 TCQGNSQWDGPEPRCVERHCS 499
Score = 34.3 bits (77), Expect = 1.3
Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 2/39 (5%)
Query: 584 PRCQTEVDEC-LSDPCPVGASCLDLPGAFFCLCPSGFTG 621
P C +VDEC + C ASCL++ G++ C C +TG
Sbjct: 1741 PSC-LDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTG 1778
Score = 33.9 bits (76), Expect = 1.6
Identities = 34/135 (25%), Positives = 49/135 (36%), Gaps = 13/135 (9%)
Query: 456 PGS-FNCLCPPGY--TGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEV 512
PGS N C PG+ G+ + N+ Q P C C PP LE
Sbjct: 1650 PGSKVNLFCDPGFQLVGNPVQYCLNQ--GQWTQPLPHC----ERISCGVPPPLENGFHSA 1703
Query: 513 ETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEE---DIDECR-SSPCANGGQCQD 568
+ S + + LL + C S D+DEC S C+ C +
Sbjct: 1704 DDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLN 1763
Query: 569 QPGAFHCKCLPGFEG 583
G++ C C+P + G
Sbjct: 1764 VDGSYICSCVPPYTG 1778
Score = 33.9 bits (76), Expect = 1.6
Identities = 71/308 (23%), Positives = 102/308 (33%), Gaps = 50/308 (16%)
Query: 646 KANCLCPDGSPGCAPPEDNC------TCHHGHCQRSSC----VCDVGWTGPECEAELGGC 695
K N C G P C T HC+R SC + G+ + + G
Sbjct: 1653 KVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCGVPPPLENGFHSAD-DFYAGST 1711
Query: 696 ISAPCAHGGTCYPQPSGYNCTCPTGYTG--PTCSEEMTACHSGPCLNGGSCNPSPGGYYC 753
++ C +G + CT + G P+C + C SC G Y C
Sbjct: 1712 VTYQCNNGYYLLGDSRMF-CTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYIC 1770
Query: 754 TCPPSHTGPQCQTSTDYCVSAP--CFNGGT-----CVNRPGTFSCLCAMGFQGPRCEGKL 806
+C P +TG + AP NG + V TFSC +G + G
Sbjct: 1771 SCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQ-----EGYQLMGVT 1825
Query: 807 RPSCADSPCRN------RATCQDSPQGPR--CLCPTGYTGGSCQTLMDLCAQKPCPRNSH 858
+ +C +S N +A P P C+ +T GS T C +
Sbjct: 1826 KITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFTFGSKVTYR--C------NKGY 1877
Query: 859 CLQTGPSFHCLCLQGW--TGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFC 916
L CL W + P+C P+ ++ G + S GL S SY C
Sbjct: 1878 TLAGDKESSCLANSSWSHSPPVCE-PVKCSSPENINNGKYILS-----GLTYLSTASYSC 1931
Query: 917 HCPPGFQG 924
QG
Sbjct: 1932 DTGYSLQG 1939
Score = 33.5 bits (75), Expect = 2.1
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
Query: 326 CRNGGTCQNSAGSFHCVCVSGWGGTSCE-ENLDDC-IAATCAPGSTCIDRVGSFSCLCPP 383
C NG + F C W G S ++D+C + + C+ ++C++ GS+ C C P
Sbjct: 1716 CNNGYYLLGDSRMF-CTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVP 1774
Query: 384 GRTG 387
TG
Sbjct: 1775 PYTG 1778
Score = 33.1 bits (74), Expect = 2.8
Identities = 66/284 (23%), Positives = 90/284 (31%), Gaps = 77/284 (27%)
Query: 509 LCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQ--- 565
LC+ E +C + C F+CIC G+ G + + C S G
Sbjct: 280 LCD-EGKDCCDR--MGSCKCGTHTGHFECICEKGYYGKGLQYECTACPSGTYKPEGSPGG 336
Query: 566 ------CQDQ-----PGAF---HCKCLPGF--EGPRCQTEVDECLSDP------------ 597
C D+ PG+ C C G+ G C+ L P
Sbjct: 337 ISSCIPCPDENHTSPPGSTSPEDCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNN 396
Query: 598 ---CPVGASC---LDLPGAFFCLC-PSGF---TGQLCEVPLCAPNLCQPKQ-----ICKD 642
G C DL G+ LC P+G + C V C P+L QPK ++
Sbjct: 397 HFNAACGVRCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTC-PHLRQPKHGHISCSTRE 455
Query: 643 QKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAH 702
K CL D TC G+ Q W GPE C+ C
Sbjct: 456 MLYKTTCLVACDEGYRLEGSDKLTC-QGNSQ---------WDGPEPR-----CVERHC-- 498
Query: 703 GGTCYPQP-----SGYNCTCPTGYTGPTCSEEMTACHSGPCLNG 741
+ + P S +NC G C +C G L+G
Sbjct: 499 --STFQMPKDVIISPHNCGKQPAKFGTIC---YVSCRQGFILSG 537
>gi|9506545 delta-like 4 protein precursor [Homo sapiens]
Length = 685
Score = 236 bits (601), Expect = 2e-61
Identities = 130/371 (35%), Positives = 177/371 (47%), Gaps = 36/371 (9%)
Query: 297 TYTCLCPETWTGWDCSEDVDECETQ-GPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEEN 355
+Y +C + + G +CS + G C+ G C+ GW G C++
Sbjct: 170 SYRVICSDNYYGDNCSRLCKKRNDHFGHYVCQPDGNLS---------CLPGWTGEYCQQP 220
Query: 356 LDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGS 415
+ C++ C CLC PG G LC+ C+ CST
Sbjct: 221 I--CLSGCHEQNGYCSKPA---ECLCRPGWQGRLCN---ECIPHNGCRHGTCST-----P 267
Query: 416 TLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNT-PGSFNCLCPPGYTGSRCEA 474
C C G+ G C QDL+ C SPC++G +C N+ S+ C C PGYTG CE
Sbjct: 268 WQCTCDEGWGGLFCDQDLNYCTHH----SPCKNGATCSNSGQRSYTCTCRPGYTGVDCEL 323
Query: 475 DHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNG 534
+ +EC S PC G +C D +HCLCPPG G CE T CA +PC N C + G
Sbjct: 324 ELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQG 383
Query: 535 --FQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDE 592
+ C C P F+G+ CE+ +D C S+PCANGGQC ++ + C+C PGF G C+ V +
Sbjct: 384 ANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSD 443
Query: 593 CLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEV----PLCAPNLCQPKQICKD--QKDK 646
C +PC G +C DL C CP+GF+G+ CEV CA + C + C D
Sbjct: 444 CARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDT 503
Query: 647 ANCLCPDGSPG 657
C CP G G
Sbjct: 504 FVCNCPYGFVG 514
Score = 224 bits (571), Expect = 7e-58
Identities = 168/539 (31%), Positives = 218/539 (40%), Gaps = 84/539 (15%)
Query: 126 FCSKRGRCHIQASGRPQCSCMPGW-TGEQCQLRDF---CSANPCVNGGVCLATYPQIQCH 181
F ++RG + ASGRP C PG T + L+ F S PC G V
Sbjct: 37 FINERG---VLASGRP---CEPGCRTFFRVCLKHFQAVVSPGPCTFGTVSTPVL------ 84
Query: 182 CPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPP- 240
G A D + ++P P + T L P +LR PP
Sbjct: 85 ---GTNSFAVRDDSSGGGRNPLQLPFNFTWPGTFS----LIIEAWHAPGDDLRPEALPPD 137
Query: 241 --------RGCSNGGTCQLMPEKDSTF------HLCLCPPGFIGPDC----EVNPDNCVS 282
+G G L+ E+ ST + +C + G +C + D+
Sbjct: 138 ALISKIAIQGSLAVGQNWLLDEQTSTLTRLRYSYRVICSDNYYGDNCSRLCKKRNDHFGH 197
Query: 283 HQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDV--DECETQGPPHCRNGGTCQNSAGSFH 340
+ CQ G C WTG C + + C Q G C A
Sbjct: 198 YVCQPDGNLS---------CLPGWTGEYCQQPICLSGCHEQN-------GYCSKPA---E 238
Query: 341 CVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DMCLSQ 399
C+C GW G C E CI TC + C C G GL C + + C
Sbjct: 239 CLCRPGWQGRLCNE----CIPHNGCRHGTCST---PWQCTCDEGWGGLFCDQDLNYCTHH 291
Query: 400 -PCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGS 458
PC A CS + T C C+PGY+G C +L EC +PC +GGSC +
Sbjct: 292 SPCKNGATCSNSGQRSYT-CTCRPGYTGVDCELELSEC-----DSNPCRNGGSCKDQEDG 345
Query: 459 FNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLL--ATFHCLCPPGLEGQLCEVETNE 516
++CLCPPGY G CE C PC G +C + A + C CPP G CE + +
Sbjct: 346 YHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDR 405
Query: 517 CASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCK 576
C S PC N C + C C PGF+GT CE + +C +PCA+GG C D C
Sbjct: 406 CTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCT 465
Query: 577 CLPGFEGPRCQ--TEVDECLSDPCPVGASCL-DLP-GAFFCLCPSGFTGQLCEVPLCAP 631
C GF G RC+ T +D C S PC A+C DL F C CP GF G CE P+ P
Sbjct: 466 CPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCEFPVGLP 524
Score = 215 bits (548), Expect = 3e-55
Identities = 115/328 (35%), Positives = 150/328 (45%), Gaps = 31/328 (9%)
Query: 615 CPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPG-----CAPPEDNCTCHH 669
C G+TG+ C+ P+C + C A CLC G G C P C H
Sbjct: 208 CLPGWTGEYCQQPICLSGCHEQNGYCSKP---AECLCRPGWQGRLCNECIPHNG---CRH 261
Query: 670 GHCQRS-SCVCDVGWTGPECEAELGGCIS-APCAHGGTCYPQPS-GYNCTCPTGYTGPTC 726
G C C CD GW G C+ +L C +PC +G TC Y CTC GYTG C
Sbjct: 262 GTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDC 321
Query: 727 SEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTC--VN 784
E++ C S PC NGGSC GY+C CPP + G C+ ST C +PCFNGG+C N
Sbjct: 322 ELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERN 381
Query: 785 RPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTL 844
+ ++C C F G CE K+ C +PC N C + C C G+TG C+
Sbjct: 382 QGANYACECPPNFTGSNCEKKV-DRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELH 440
Query: 845 MDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNL--PLSSCQKAALSQGIDVSSLCH 902
+ CA+ PC C C C G++G C + + +C SS C
Sbjct: 441 VSDCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDAC----------ASSPCF 490
Query: 903 NGGLCVD--SGPSYFCHCPPGFQGSLCQ 928
N C S ++ C+CP GF GS C+
Sbjct: 491 NRATCYTDLSTDTFVCNCPYGFVGSRCE 518
Score = 211 bits (537), Expect = 6e-54
Identities = 117/344 (34%), Positives = 150/344 (43%), Gaps = 33/344 (9%)
Query: 832 CPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAAL 891
C G+TG CQ +C +N +C + CLC GW G LCN
Sbjct: 208 CLPGWTGEYCQ--QPICLSGCHEQNGYCSKPA---ECLCRPGWQGRLCN----------- 251
Query: 892 SQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESR-PCQNGATCM-AQP 949
+ HNG + C C G+ G C +N C PC+NGATC +
Sbjct: 252 ------ECIPHNGCRHGTCSTPWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQ 305
Query: 950 SGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDE 1009
Y C C PGY G +C EL C S PC N G+C + G+HC CPPG+ GL CE
Sbjct: 306 RSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLS 365
Query: 1010 CLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPL 1069
C D PC G+ + + C+C P TG CE ++D C S PC +GG C S +
Sbjct: 366 CADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRM 425
Query: 1070 GFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPP 1129
C C GF G C C + C HGG C + G C C +G+ G C
Sbjct: 426 ---CRCRPGFTGTYCELHVSDCARNPCAHGGTC-HDLENGL--MCTCPAGFSGRRCEVRT 479
Query: 1130 APKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKP 1173
+ C SPC +C T L F C+CP+ G RC+ P
Sbjct: 480 SIDACA-SSPCFNRATC--YTDLSTDTFVCNCPYGFVGSRCEFP 520
Score = 206 bits (525), Expect = 1e-52
Identities = 118/351 (33%), Positives = 147/351 (41%), Gaps = 28/351 (7%)
Query: 702 HGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTG 761
H G QP G N +C G+TG C + + C SG G C+ C C P G
Sbjct: 194 HFGHYVCQPDG-NLSCLPGWTGEYCQQPI--CLSGCHEQNGYCSKPAE---CLCRPGWQG 247
Query: 762 PQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATC 821
C C+ GTC + C C G+ G C+ L SPC+N ATC
Sbjct: 248 RLCNE----CIPHNGCRHGTCST---PWQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATC 300
Query: 822 QDSPQGP-RCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCN 880
+S Q C C GYTG C+ + C PC C +HCLC G+ G C
Sbjct: 301 SNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCE 360
Query: 881 LPLSSCQKAALSQGIDVSSLCHNGGLCVD--SGPSYFCHCPPGFQGSLCQDHVNPCESRP 938
SC S C NGG C + G +Y C CPP F GS C+ V+ C S P
Sbjct: 361 HSTLSC----------ADSPCFNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNP 410
Query: 939 CQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGF 998
C NG C+ + +C+C PG+ G C + C PC + GTC G C CP GF
Sbjct: 411 CANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARNPCAHGGTCHDLENGLMCTCPAGF 470
Query: 999 VGLRCE--GDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEI 1047
G RCE +D C PC T + F C C G G CE +
Sbjct: 471 SGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCEFPV 521
Score = 206 bits (523), Expect = 2e-52
Identities = 132/395 (33%), Positives = 176/395 (44%), Gaps = 51/395 (12%)
Query: 92 SSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKR----GRCHIQASGRPQCSCMP 147
S+ + L S+ C + G+ C C KR G Q G SC+P
Sbjct: 162 STLTRLRYSYRVICSDNYYGDNCSR---------LCKKRNDHFGHYVCQPDGN--LSCLP 210
Query: 148 GWTGEQCQLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPK 207
GWTGE CQ + C + G C +C C PG++G C NEC G C
Sbjct: 211 GWTGEYCQ-QPICLSGCHEQNGYCSKP---AECLCRPGWQGRLC----NECIPHNG-CRH 261
Query: 208 GTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRG-CSNGGTCQLMPEKDSTFHLCLCPP 266
GT C +QC C G G C+ C C NG TC ++ T C C P
Sbjct: 262 GT-CSTP---WQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYT---CTCRP 314
Query: 267 GFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHC 326
G+ G DCE+ C S+ C+NGG+C+D D Y CLCP + G C C C
Sbjct: 315 GYTGVDCELELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSC---ADSPC 371
Query: 327 RNGGTC--QNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPG 384
NGG+C +N ++ C C + G++CE+ +D C + CA G C++R S C C PG
Sbjct: 372 FNGGSCRERNQGANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPG 431
Query: 385 RTGLLC--HLEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTC--HQDLDECLMAQ 440
TG C H+ D C PC C + L +C C G+SG C +D C
Sbjct: 432 FTGTYCELHVSD-CARNPCAHGGTC--HDLENGLMCTCPAGFSGRRCEVRTSIDAC---- 484
Query: 441 QGPSPCEHGGSCLN--TPGSFNCLCPPGYTGSRCE 473
SPC + +C + +F C CP G+ GSRCE
Sbjct: 485 -ASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRCE 518
Score = 202 bits (513), Expect = 3e-51
Identities = 129/380 (33%), Positives = 176/380 (46%), Gaps = 51/380 (13%)
Query: 338 SFHCVCVSGWGGTSC----EENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE 393
S+ +C + G +C ++ D C P G+ SCL PG TG C +
Sbjct: 170 SYRVICSDNYYGDNCSRLCKKRNDHFGHYVCQPD-------GNLSCL--PGWTGEYCQ-Q 219
Query: 394 DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCL 453
+CLS CH + P CLC+PG+ G C+ EC+ + C HG +C
Sbjct: 220 PICLSG-CHEQNGYCSKPAE----CLCRPGWQGRLCN----ECIPH----NGCRHG-TC- 264
Query: 454 NTPGSFNCLCPPGYTGSRCEADHNECLSQ-PCHPGSTCLDL-LATFHCLCPPGLEGQLCE 511
+TP + C C G+ G C+ D N C PC G+TC + ++ C C PG G CE
Sbjct: 265 STP--WQCTCDEGWGGLFCDQDLNYCTHHSPCKNGATCSNSGQRSYTCTCRPGYTGVDCE 322
Query: 512 VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQD--Q 569
+E +EC S PC N C D +G+ C+C PG+ G CE C SPC NGG C++ Q
Sbjct: 323 LELSECDSNPCRNGGSCKDQEDGYHCLCPPGYYGLHCEHSTLSCADSPCFNGGSCRERNQ 382
Query: 570 PGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCEVPL- 628
+ C+C P F G C+ +VD C S+PC G CL+ + C C GFTG CE+ +
Sbjct: 383 GANYACECPPNFTGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVS 442
Query: 629 -CAPNLCQPKQICKDQKDKANCLCPDGSPG-----------CA--PPEDNCTCHHG-HCQ 673
CA N C C D ++ C CP G G CA P + TC+
Sbjct: 443 DCARNPCAHGGTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTD 502
Query: 674 RSSCVCDVGWTGPECEAELG 693
C C G+ G CE +G
Sbjct: 503 TFVCNCPYGFVGSRCEFPVG 522
Score = 186 bits (471), Expect = 3e-46
Identities = 116/349 (33%), Positives = 156/349 (44%), Gaps = 42/349 (12%)
Query: 49 GTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPG 108
G C PG+ GE CQ P +C +G Q G S P+ C C PG
Sbjct: 204 GNLSCLPGWTGEYCQQP-------ICLSGCHEQN------GYCSKPAE------CLCRPG 244
Query: 109 FTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQC-QLRDFCS-ANPCV 166
+ G C + C P + G C S QC+C GW G C Q ++C+ +PC
Sbjct: 245 WQGRLC-----NECIPHNGCRHGTC----STPWQCTCDEGWGGLFCDQDLNYCTHHSPCK 295
Query: 167 NGGVCL-ATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG 225
NG C + C C PG+ G CE +++EC D PC G SC + + CLCP G
Sbjct: 296 NGATCSNSGQRSYTCTCRPGYTGVDCELELSEC--DSNPCRNGGSCKDQEDGYHCLCPPG 353
Query: 226 QEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQC 285
G CE C C NGG+C+ + C CPP F G +CE D C S+ C
Sbjct: 354 YYGLHCEHSTLSCADSPCFNGGSCR--ERNQGANYACECPPNFTGSNCEKKVDRCTSNPC 411
Query: 286 QNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVS 345
NGG C + + C C +TG C V +C + P C +GGTC + C C +
Sbjct: 412 ANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDC-ARNP--CAHGGTCHDLENGLMCTCPA 468
Query: 346 GWGGTSCE--ENLDDCIAATCAPGSTCIDRVG--SFSCLCPPGRTGLLC 390
G+ G CE ++D C ++ C +TC + +F C CP G G C
Sbjct: 469 GFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDTFVCNCPYGFVGSRC 517
Score = 159 bits (402), Expect = 3e-38
Identities = 86/245 (35%), Positives = 112/245 (45%), Gaps = 23/245 (9%)
Query: 34 PCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSS 93
PC NG TC + TC C PG+ G C+ ++ C+NGGSC+
Sbjct: 293 PCKNGATCSNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSCK------------ 340
Query: 94 PSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASG-RPQCSCMPGWTGE 152
+ C C PG+ G C+ C S C G C + G C C P +TG
Sbjct: 341 --DQEDGYHCLCPPGYYGLHCEHSTLS-CADSPCFNGGSCRERNQGANYACECPPNFTGS 397
Query: 153 QCQLR-DFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSC 211
C+ + D C++NPC NGG CL P C C PGF G CE V++C ++ PC G +C
Sbjct: 398 NCEKKVDRCTSNPCANGGQCLNRGPSRMCRCRPGFTGTYCELHVSDCARN--PCAHGGTC 455
Query: 212 HNTLGSFQCLCPVGQEGPRCELRAG--PCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFI 269
H+ C CP G G RCE+R C C N TC D+ +C CP GF+
Sbjct: 456 HDLENGLMCTCPAGFSGRRCEVRTSIDACASSPCFNRATCYTDLSTDT--FVCNCPYGFV 513
Query: 270 GPDCE 274
G CE
Sbjct: 514 GSRCE 518
Score = 95.5 bits (236), Expect = 5e-19
Identities = 106/406 (26%), Positives = 147/406 (36%), Gaps = 86/406 (21%)
Query: 952 YLCQCAPGYDGQNCSKELDACQSQPCH-NHGTCTPKPGGFHCACPPGFVGLRCEGDV--- 1007
Y C+ Y G NCS+ C+ + H H C P + +C PG+ G C+ +
Sbjct: 171 YRVICSDNYYGDNCSR---LCKKRNDHFGHYVCQPDG---NLSCLPGWTGEYCQQPICLS 224
Query: 1008 ------------DECLDQP---------CHPTGTAACHSLANAFYCQCLPGHTGQWCEVE 1046
ECL +P C P + + + C C G G +C+ +
Sbjct: 225 GCHEQNGYCSKPAECLCRPGWQGRLCNECIPHNGCRHGTCSTPWQCTCDEGWGGLFCDQD 284
Query: 1047 IDPC-HSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPS 1105
++ C H PC +G TC + + C C G+ G C C + C +GG C
Sbjct: 285 LNYCTHHSPCKNGATC--SNSGQRSYTCTCRPGYTGVDCELELSECDSNPCRNGGSC-KD 341
Query: 1106 PKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSS 1165
+ G+ C C GY G C + C SPC GSC E G + C CP +
Sbjct: 342 QEDGY--HCLCPPGYYGLHC--EHSTLSCA-DSPCFNGGSCRERN--QGANYACECPPNF 394
Query: 1166 PGPRCQK--------PGAKG--CEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCP 1215
G C+K P A G C R C PG + G C L V D +
Sbjct: 395 TGSNCEKKVDRCTSNPCANGGQCLNRGPSRMCRC---RPG--FTGTYCELHVSDCARNPC 449
Query: 1216 SHSRCWLLFRDGQCHPQCDSEECL----FDGYDCETPPACTPAYDQYCHDHFHNGHC--E 1269
+H G CH + C F G CE + C F+ C +
Sbjct: 450 AHG--------GTCHDLENGLMCTCPAGFSGRRCEVRTSIDACASSPC---FNRATCYTD 498
Query: 1270 KGCNTAEC----GWDGGDCRPEDGDP---EW-----GPSLALLVVL 1303
+T C G+ G C G P W G LA+L+VL
Sbjct: 499 LSTDTFVCNCPYGFVGSRCEFPVGLPPSFPWVAVSLGVGLAVLLVL 544
>gi|110735443 delta-like 1 [Homo sapiens]
Length = 723
Score = 230 bits (586), Expect = 1e-59
Identities = 140/421 (33%), Positives = 173/421 (41%), Gaps = 63/421 (14%)
Query: 713 YNCTCPTGYTGPTCS----EEMTACHSGPCLNGGS--CNPSPGGYYCTCPPSHTGPQCQT 766
Y C Y G CS A C G CNP G YCT P G C
Sbjct: 175 YRFVCDEHYYGEGCSVFCRPRDDAFGHFTCGERGEKVCNPGWKGPYCTEPICLPG--CDE 232
Query: 767 STDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLR-PSCADSPCRNRATCQDSP 825
+C ++PG C C +G+QG C+ +R P C C+
Sbjct: 233 QHGFC------------DKPG--ECKCRVGWQGRYCDECIRYPGCLHGTCQ--------- 269
Query: 826 QGPRCLCPTGYTGGSCQTLMDLCAQ-KPCPRNSHCLQTGP-SFHCLCLQGWTGPLCNLPL 883
Q +C C G+ G C ++ C KPC + C TG S+ C C G+TG C L +
Sbjct: 270 QPWQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGI 329
Query: 884 SSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGA 943
C S C NGG C D SY C CPPGF G +C+ C PC NG
Sbjct: 330 DECDP----------SPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGG 379
Query: 944 TCMAQPSG-YLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLR 1002
C P G Y C+C GY G NC K++D C S PC N C + C C GF G
Sbjct: 380 RCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRH 439
Query: 1003 CEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCE 1062
C+ +VD+C PC GT C N F C C PG+TG+ C + C PC +G TC
Sbjct: 440 CDDNVDDCASSPCANGGT--CRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCH 497
Query: 1063 ATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGG 1122
++C C +G+ GP C P LP P P L G GG
Sbjct: 498 ERGHR---YVCECARGYGGPNCQFLLPE------------LP-PGPAVVDLTEKLEGQGG 541
Query: 1123 P 1123
P
Sbjct: 542 P 542
Score = 227 bits (578), Expect = 1e-58
Identities = 133/404 (32%), Positives = 178/404 (44%), Gaps = 44/404 (10%)
Query: 481 SQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICL 540
SQ H S DL ++ +C G+ C V A H C + + +C
Sbjct: 160 SQDLH-SSGRTDLKYSYRFVCDEHYYGEGCSVFCRPRDDA--FGHFTCGER---GEKVCN 213
Query: 541 PGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPV 600
PG+ G C E I C G C D+PG CKC G++G C DEC+ P +
Sbjct: 214 PGWKGPYCTEPI--CLPGCDEQHGFC-DKPG--ECKCRVGWQGRYC----DECIRYPGCL 264
Query: 601 GASCLDLPGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAP 660
+C + C C G+ G C L N C + CK+
Sbjct: 265 HGTCQQ---PWQCNCQEGWGGLFCNQDL---NYCTHHKPCKN------------------ 300
Query: 661 PEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTG 720
TC + +C C G+TG CE + C +PC +GG+C + Y+CTCP G
Sbjct: 301 ---GATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPG 357
Query: 721 YTGPTCSEEMTACHSGPCLNGGSCNPSP-GGYYCTCPPSHTGPQCQTSTDYCVSAPCFNG 779
+ G C C GPC NGG C+ SP GGY C CP ++G C+ DYC S+PC NG
Sbjct: 358 FYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNG 417
Query: 780 GTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGG 839
CV+ + C C GF G C+ + CA SPC N TC+D C CP GYTG
Sbjct: 418 AKCVDLGDAYLCRCQAGFSGRHCDDNV-DDCASSPCANGGTCRDGVNDFSCTCPPGYTGR 476
Query: 840 SCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPL 883
+C + C PC + C + G + C C +G+ GP C L
Sbjct: 477 NCSAPVSRCEHAPCHNGATCHERGHRYVCECARGYGGPNCQFLL 520
Score = 223 bits (568), Expect = 1e-57
Identities = 134/396 (33%), Positives = 183/396 (46%), Gaps = 42/396 (10%)
Query: 217 SFQCLCPVGQEGPRCELRAGPCPPRGCSNGG-TCQLMPEKDSTFHLCLCPPGFIGPDCEV 275
S++ +C G C + C PR + G TC EK +C PG+ GP C
Sbjct: 174 SYRFVCDEHYYGEGCSVF---CRPRDDAFGHFTCGERGEK-------VCNPGWKGPYC-- 221
Query: 276 NPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNS 335
C+ + G C + C C W G C DEC P C +G TCQ
Sbjct: 222 TEPICLPGCDEQHGFCDKPGE---CKCRVGWQGRYC----DECIRY--PGCLHG-TCQQP 271
Query: 336 AGSFHCVCVSGWGGTSCEENLDDCIA-ATCAPGSTCIDR-VGSFSCLCPPGRTGLLCHLE 393
+ C C GWGG C ++L+ C C G+TC + GS++C C PG TG C L
Sbjct: 272 ---WQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELG 328
Query: 394 -DMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSC 452
D C PC C+ L S C C PG+ G C C PC +GG C
Sbjct: 329 IDECDPSPCKNGGSCTD--LENSYSCTCPPGFYGKICELSAMTC-----ADGPCFNGGRC 381
Query: 453 LNTP-GSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCE 511
++P G ++C CP GY+G CE + C S PC G+ C+DL + C C G G+ C+
Sbjct: 382 SDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCD 441
Query: 512 VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPG 571
++CAS+PC N C D +N F C C PG++G C + C +PC NG C ++
Sbjct: 442 DNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGH 501
Query: 572 AFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDL 607
+ C+C G+ GP CQ + E P G + +DL
Sbjct: 502 RYVCECARGYGGPNCQFLLPE-----LPPGPAVVDL 532
Score = 215 bits (548), Expect = 3e-55
Identities = 135/413 (32%), Positives = 180/413 (43%), Gaps = 68/413 (16%)
Query: 338 SFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSC------LCPPGRTGLLCH 391
S+ VC + G C + C P D G F+C +C PG G C
Sbjct: 174 SYRFVCDEHYYGEGC--------SVFCRPRD---DAFGHFTCGERGEKVCNPGWKGPYC- 221
Query: 392 LEDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGS 451
E +CL C D Q G C C+ G+ G C DEC+ C HG +
Sbjct: 222 TEPICLPG-C--DEQHGFCDKPGE--CKCRVGWQGRYC----DECIRYPG----CLHG-T 267
Query: 452 CLNTPGSFNCLCPPGYTGSRCEADHNECLS-QPCHPGSTCLDL-LATFHCLCPPGLEGQL 509
C + C C G+ G C D N C +PC G+TC + ++ C C PG G
Sbjct: 268 CQQP---WQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGAT 324
Query: 510 CEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQ 569
CE+ +EC +PC N C DL N + C C PGF G CE C PC NGG+C D
Sbjct: 325 CELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDS 384
Query: 570 P-GAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPSGFTGQLCE--V 626
P G + C+C G+ G C+ ++D C S PC GA C+DL A+ C C +GF+G+ C+ V
Sbjct: 385 PDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNV 444
Query: 627 PLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGP 686
CA + C C+D + +C CP G+TG
Sbjct: 445 DDCASSPCANGGTCRDGVNDFSCTCPP----------------------------GYTGR 476
Query: 687 ECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPCL 739
C A + C APC +G TC+ + Y C C GY GP C + GP +
Sbjct: 477 NCSAPVSRCEHAPCHNGATCHERGHRYVCECARGYGGPNCQFLLPELPPGPAV 529
Score = 214 bits (546), Expect = 5e-55
Identities = 131/398 (32%), Positives = 168/398 (42%), Gaps = 63/398 (15%)
Query: 92 SSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRC--HIQASGRPQCSCMPGW 149
S + L S+ C + GE C FC R H R + C PGW
Sbjct: 166 SGRTDLKYSYRFVCDEHYYGEGCSV---------FCRPRDDAFGHFTCGERGEKVCNPGW 216
Query: 150 TGEQC----------QLRDFCS---------------ANPCVNGGVCL--ATYPQIQCHC 182
G C + FC + C+ CL QC+C
Sbjct: 217 KGPYCTEPICLPGCDEQHGFCDKPGECKCRVGWQGRYCDECIRYPGCLHGTCQQPWQCNC 276
Query: 183 PPGFEGHACERDVNECFQDPGPCPKGTSCHNT-LGSFQCLCPVGQEGPRCELRAGPCPPR 241
G+ G C +D+N C PC G +C NT GS+ C C G G CEL C P
Sbjct: 277 QEGWGGLFCNQDLNYCTHHK-PCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPS 335
Query: 242 GCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNGGTCQDGLD-TYTC 300
C NGG+C + S C CPPGF G CE++ C C NGG C D D Y+C
Sbjct: 336 PCKNGGSCTDLENSYS----CTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSC 391
Query: 301 LCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCI 360
CP ++G++C + +D C + C NG C + ++ C C +G+ G C++N+DDC
Sbjct: 392 RCPVGYSGFNCEKKIDYCSSS---PCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCA 448
Query: 361 AATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLE-DMCLSQPCHGDAQCSTNPLTGSTLCL 419
++ CA G TC D V FSC CPPG TG C C PCH A C + +C
Sbjct: 449 SSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATC--HERGHRYVCE 506
Query: 420 CQPGYSGPTCH------------QDLDECLMAQQGPSP 445
C GY GP C DL E L Q GP P
Sbjct: 507 CARGYGGPNCQFLLPELPPGPAVVDLTEKLEGQGGPFP 544
Score = 198 bits (503), Expect = 5e-50
Identities = 118/367 (32%), Positives = 158/367 (43%), Gaps = 44/367 (11%)
Query: 458 SFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHC------LCPPGLEGQLCE 511
S+ +C Y G C S C P D F C +C PG +G C
Sbjct: 174 SYRFVCDEHYYGEGC--------SVFCRPRD---DAFGHFTCGERGEKVCNPGWKGPYCT 222
Query: 512 VETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPG 571
C H C +C C G+ G C DEC P G CQ QP
Sbjct: 223 EPI--CLPGCDEQHGFCD---KPGECKCRVGWQGRYC----DECIRYPGCLHGTCQ-QP- 271
Query: 572 AFHCKCLPGFEGPRCQTEVDECLSD-PCPVGASCLDL-PGAFFCLCPSGFTGQLCEVPL- 628
+ C C G+ G C +++ C PC GA+C + G++ C C G+TG CE+ +
Sbjct: 272 -WQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPGYTGATCELGID 330
Query: 629 -CAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRS-----------S 676
C P+ C+ C D ++ +C CP G G TC G C S
Sbjct: 331 ECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYS 390
Query: 677 CVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSG 736
C C VG++G CE ++ C S+PC++G C Y C C G++G C + + C S
Sbjct: 391 CRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASS 450
Query: 737 PCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMG 796
PC NGG+C + CTCPP +TG C C APC NG TC R + C CA G
Sbjct: 451 PCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYVCECARG 510
Query: 797 FQGPRCE 803
+ GP C+
Sbjct: 511 YGGPNCQ 517
Score = 191 bits (486), Expect = 5e-48
Identities = 116/346 (33%), Positives = 149/346 (43%), Gaps = 39/346 (11%)
Query: 48 QGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLP 107
+G C PG+ G C P +C G Q G P C C
Sbjct: 207 RGEKVCNPGWKGPYCTEP-------ICLPGCDEQH------GFCDKPGE------CKCRV 247
Query: 108 GFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQC-QLRDFCSAN-PC 165
G+ G C + P G H QC+C GW G C Q ++C+ + PC
Sbjct: 248 GWQGRYCDECIRYP---------GCLHGTCQQPWQCNCQEGWGGLFCNQDLNYCTHHKPC 298
Query: 166 VNGGVCLAT-YPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPV 224
NG C T C C PG+ G CE ++EC DP PC G SC + S+ C CP
Sbjct: 299 KNGATCTNTGQGSYTCSCRPGYTGATCELGIDEC--DPSPCKNGGSCTDLENSYSCTCPP 356
Query: 225 GQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQ 284
G G CEL A C C NGG C P+ + C CP G+ G +CE D C S
Sbjct: 357 GFYGKICELSAMTCADGPCFNGGRCSDSPDGG---YSCRCPVGYSGFNCEKKIDYCSSSP 413
Query: 285 CQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCVCV 344
C NG C D D Y C C ++G C ++VD+C + C NGGTC++ F C C
Sbjct: 414 CSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASS---PCANGGTCRDGVNDFSCTCP 470
Query: 345 SGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLC 390
G+ G +C + C A C G+TC +R + C C G G C
Sbjct: 471 PGYTGRNCSAPVSRCEHAPCHNGATCHERGHRYVCECARGYGGPNC 516
Score = 176 bits (447), Expect = 2e-43
Identities = 123/425 (28%), Positives = 162/425 (38%), Gaps = 66/425 (15%)
Query: 788 TFSCLCAMGFQGPRCEGKLRP--------SCADSPCRNRATCQDSPQGPRCLCPTGYTGG 839
++ +C + G C RP +C + R C +GP C P
Sbjct: 174 SYRFVCDEHYYGEGCSVFCRPRDDAFGHFTCGE---RGEKVCNPGWKGPYCTEP------ 224
Query: 840 SCQTLMDLCAQKPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSS 899
+C ++ C + G C C GW G C+ + I
Sbjct: 225 -------ICLPGCDEQHGFCDKPG---ECKCRVGWQGRYCD------------ECIRYPG 262
Query: 900 LCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPC-ESRPCQNGATCMAQPSG-YLCQCA 957
H G C + C+C G+ G C +N C +PC+NGATC G Y C C
Sbjct: 263 CLH--GTCQQP---WQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCR 317
Query: 958 PGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHP 1017
PGY G C +D C PC N G+CT + C CPPGF G CE C D PC
Sbjct: 318 PGYTGATCELGIDECDPSPCKNGGSCTDLENSYSCTCPPGFYGKICELSAMTCADGPCFN 377
Query: 1018 TGTAACHSLANAFYCQCLPGHTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPK 1077
G + S + C+C G++G CE +ID C S PC +G C + ++C C
Sbjct: 378 GGRCS-DSPDGGYSCRCPVGYSGFNCEKKIDYCSSSPCSNGAKCVDLGDA---YLCRCQA 433
Query: 1078 GFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPP 1137
GF G C C C +GG C C C GY G +C AP
Sbjct: 434 GFSGRHCDDNVDDCASSPCANGGTCRDGVNDF---SCTCPPGYTGRNC---SAPVSRCEH 487
Query: 1138 SPCLYNGSCSE---------TTGLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACD 1188
+PC +C E G GGP + P PGP K EG+ G
Sbjct: 488 APCHNGATCHERGHRYVCECARGYGGPNCQFLLPELPPGPAVVDLTEK-LEGQGGPFPWV 546
Query: 1189 AGCSG 1193
A C+G
Sbjct: 547 AVCAG 551
Score = 163 bits (413), Expect = 1e-39
Identities = 83/244 (34%), Positives = 114/244 (46%), Gaps = 24/244 (9%)
Query: 33 EPCANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLP 91
+PC NG TC + G TC C PG+ G TC+ D C + C+NGGSC
Sbjct: 296 KPCKNGATCTNTGQGSYTCSCRPGYTGATCELGIDECDPSP-CKNGGSC----------- 343
Query: 92 SSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTG 151
+ L S+ CTC PGF G+ C+ C C GRC G C C G++G
Sbjct: 344 ---TDLENSYSCTCPPGFYGKICELSAM-TCADGPCFNGGRCSDSPDGGYSCRCPVGYSG 399
Query: 152 EQCQLR-DFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTS 210
C+ + D+CS++PC NG C+ C C GF G C+ +V++C PC G +
Sbjct: 400 FNCEKKIDYCSSSPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCAS--SPCANGGT 457
Query: 211 CHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIG 270
C + + F C CP G G C C C NG TC + ++C C G+ G
Sbjct: 458 CRDGVNDFSCTCPPGYTGRNCSAPVSRCEHAPCHNGATCHERGHR----YVCECARGYGG 513
Query: 271 PDCE 274
P+C+
Sbjct: 514 PNCQ 517
Score = 131 bits (329), Expect = 8e-30
Identities = 108/368 (29%), Positives = 138/368 (37%), Gaps = 62/368 (16%)
Query: 918 CPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPC 977
C PG++G C + P C +P C+C G+ G+ C D C P
Sbjct: 212 CNPGWKGPYCTE---PICLPGCDEQHGFCDKPGE--CKCRVGWQGRYC----DECIRYPG 262
Query: 978 HNHGTCTPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPG 1037
HGTC + C C G+ GL C D++ C G ++ ++ C C PG
Sbjct: 263 CLHGTCQQP---WQCNCQEGWGGLFCNQDLNYCTHHKPCKNGATCTNTGQGSYTCSCRPG 319
Query: 1038 HTGQWCEVEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCH 1097
+TG CE+ ID C PC +GG+C S + C CP GF G C A +C C
Sbjct: 320 YTGATCELGIDECDPSPCKNGGSCTDLENS---YSCTCPPGFYGKICELSAMTCADGPCF 376
Query: 1098 HGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGF 1157
+GG C SP G+ C C GY G +C C SPC C + G +
Sbjct: 377 NGGRCSDSPDGGY--SCRCPVGYSGFNC--EKKIDYCS-SSPCSNGAKCVDL----GDAY 427
Query: 1158 RCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSH 1217
C RCQ G GR D D S P N GG C GV D CP
Sbjct: 428 LC---------RCQ----AGFSGRHCDDNVDDCASSPCAN--GGTCRDGVNDFSCTCP-- 470
Query: 1218 SRCWLLFRDGQCHPQCDSEECLFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAEC 1277
P C CE P A CH+ H CE
Sbjct: 471 -------------PGYTGRNCSAPVSRCEHAPCHNGA---TCHERGHRYVCE-----CAR 509
Query: 1278 GWDGGDCR 1285
G+ G +C+
Sbjct: 510 GYGGPNCQ 517
Score = 129 bits (324), Expect = 3e-29
Identities = 70/210 (33%), Positives = 92/210 (43%), Gaps = 19/210 (9%)
Query: 32 PEPCANGGTCLSLSLGQGTCQCAPGFLGETCQFPDPCQNAQLCQNGGSCQALLPAPLGLP 91
P PC NGG+C L +C C PGF G+ C+ C NGG C
Sbjct: 334 PSPCKNGGSCTDLE-NSYSCTCPPGFYGKICELSAMTCADGPCFNGGRC----------- 381
Query: 92 SSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTG 151
S SP + C C G++G C+ K+ D C S CS +C + C C G++G
Sbjct: 382 -SDSP-DGGYSCRCPVGYSGFNCEKKI-DYCSSSPCSNGAKC-VDLGDAYLCRCQAGFSG 437
Query: 152 EQCQLR-DFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTS 210
C D C+++PC NGG C C CPPG+ G C V+ C + PC G +
Sbjct: 438 RHCDDNVDDCASSPCANGGTCRDGVNDFSCTCPPGYTGRNCSAPVSRC--EHAPCHNGAT 495
Query: 211 CHNTLGSFQCLCPVGQEGPRCELRAGPCPP 240
CH + C C G GP C+ PP
Sbjct: 496 CHERGHRYVCECARGYGGPNCQFLLPELPP 525
>gi|194328809 latent transforming growth factor beta binding protein 3
isoform 1 [Homo sapiens]
Length = 1303
Score = 217 bits (553), Expect = 8e-56
Identities = 219/771 (28%), Positives = 285/771 (36%), Gaps = 167/771 (21%)
Query: 158 DFCSANPCVNG-GVCLATYPQIQCHCPPGFEGHACER---DVNECFQDPGPCPKGTS-CH 212
D C N + G G C+ P CHC PG+ H R DVNEC + PC G C
Sbjct: 576 DECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNEC--EAEPCGPGRGICM 633
Query: 213 NTLGSFQCLCP------VGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPP 266
NT GS+ C C VG G C P C +GG C P + C C P
Sbjct: 634 NTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGH----YKCNCYP 689
Query: 267 GFI-----GPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETW---TGWDCSEDVDEC 318
G+ P CE + D C G C++ ++ C+ + G DV+EC
Sbjct: 690 GYRLKASRPPVCE-DIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNEC 748
Query: 319 ETQGPPHCRNGGTCQNSAGSFHCVCVSGWG----GTSCEENLDDCIAATCAPGSTCIDRV 374
P C + G C+N GSF C C G+ G SC + +D+C A C +
Sbjct: 749 AEGSP--C-SPGWCENLPGSFRCTCAQGYAPAPDGRSCLD-VDECEAGDVCDNGICSNTP 804
Query: 375 GSFSCLCPPG----RTGLLCHLEDMC-LSQPCHGDAQCSTNPLTGSTLCLCQPGY---SG 426
GSF C C G R C D C C G +TN GS CLC G+ G
Sbjct: 805 GSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTN---GSYRCLCPQGHRLVGG 861
Query: 427 PTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNEC--LSQPC 484
C QD+DEC Q PS C G+C N GS+ C+C G+T ++ D + C + QP
Sbjct: 862 RKC-QDIDEC---SQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQ---DQHGCEEVEQPH 914
Query: 485 HPGST---------CLDLLAT-------------------------------FHCLCPPG 504
H C +LAT FH LCP G
Sbjct: 915 HKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDG 974
Query: 505 LE----------GQLCEVETNECA--SAPCLNHADCHDLLNGFQCICLPGF--SGTRCE- 549
G + +EC + C + G++C C GF G E
Sbjct: 975 KGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQGFYYDGNLLEC 1034
Query: 550 EDIDECRSSPCANGGQCQDQPGAFHCKCLPGFEGPRCQTE--------VDECLSDPCPVG 601
D+DEC G C++ G + C C P E Q + VDEC
Sbjct: 1035 VDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPAACRP 1094
Query: 602 ASCLDLPGAFFCLC-------PSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDG 654
C++LPG++ C C PSG QL E P A + + +C Q+ + +C
Sbjct: 1095 GRCVNLPGSYRCECRPPWVPGPSGRDCQLPESP--AERAPERRDVCWSQRGEDG-MCAGP 1151
Query: 655 SPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPC------AHGGTCYP 708
G A D+C C G GW G +C PC +H T
Sbjct: 1152 LAGPALTFDDCCCRQGR----------GW-GAQCR---------PCPPRGAGSHCPTSQS 1191
Query: 709 QPSGYNCTCPTGYTGPTCSEEMTACHSGPC-LNGGSCNPSPGGYYCTCPPSHTGPQCQTS 767
+ + + T P P E+ + S C G C P PGG C CP G Q S
Sbjct: 1192 ESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPG---GFQLDAS 1248
Query: 768 TDYCVSAP----------CFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRP 808
CV CVN G+F C+C GF R G P
Sbjct: 1249 RARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKAGFARSRPHGACVP 1299
Score = 197 bits (502), Expect = 7e-50
Identities = 211/767 (27%), Positives = 285/767 (37%), Gaps = 176/767 (22%)
Query: 352 CEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTG----LLCHLEDMCLSQPCHGDAQC 407
C N + C C PG +SC C PG C + C ++PC G +
Sbjct: 578 CRLNQNICGHGECVPGPP------DYSCHCNPGYRSHPQHRYCVDVNECEAEPC-GPGRG 630
Query: 408 STNPLTGSTLCLCQPGY------SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNC 461
GS C C GY G +C DL+EC P C GG C+N PG + C
Sbjct: 631 ICMNTGGSYNCHCNRGYRLHVGAGGRSC-VDLNECAK----PHLCGDGGFCINFPGHYKC 685
Query: 462 LCPPGYT--GSR---CEADHNECLSQPCHPGSTCLDLLATFHCL-CPPGLEGQ---LCEV 512
C PGY SR CE D +EC P C + +F C+ C PG Q C
Sbjct: 686 NCYPGYRLKASRPPVCE-DIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACR- 743
Query: 513 ETNECASAPCLNHADCHDLLNGFQCICLPGFS----GTRCEEDIDECRSSPCANGGQCQD 568
+ NECA + C +L F+C C G++ G C D+DEC + + G C +
Sbjct: 744 DVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCL-DVDECEAGDVCDNGICSN 802
Query: 569 QPGAFHCKCLPGFEGPRCQT---EVDECLSDPCPVGASCLDLPGAFFCLCPSGFT---GQ 622
PG+F C+CL G+ R ++ ++DEC +G C++ G++ CLCP G G+
Sbjct: 803 TPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGR 862
Query: 623 LC-EVPLCA--PNLCQPKQICKDQKDKANCLCPDG------SPGCAPPE----------- 662
C ++ C+ P+LC P CK+ + C+C +G GC E
Sbjct: 863 KCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLN 922
Query: 663 -----------------DNCTCHHG-----HCQ------------RSSCVCDVGWT---- 684
C C G HC+ S C G+T
Sbjct: 923 FDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNN 982
Query: 685 ----GPECEAELGGCI---SAPCAHGGTCYPQPSGYNCTCPTG--YTGP--TCSEEMTAC 733
G ++ C+ S C G QP GY C C G Y G C +
Sbjct: 983 IVNYGIPAHRDIDECMLFGSEICKEGKCVNTQP-GYECYCKQGFYYDGNLLECVDVDECL 1041
Query: 734 HSGPCLNGGSCNPSPGGYYCTC-PPSHTGP---QC----QTSTDYCVSAPCFNGGTCVNR 785
C N G C + GGY C C PP+ P QC + D C G CVN
Sbjct: 1042 DESNCRN-GVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPAACRPGRCVNL 1100
Query: 786 PGTFSCLC----AMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSC 841
PG++ C C G G C+ L S A+ R C S +G +C G G
Sbjct: 1101 PGSYRCECRPPWVPGPSGRDCQ--LPESPAERAPERRDVCW-SQRGEDGMC-AGPLAGPA 1156
Query: 842 QTLMDLCAQ---------KPCP---RNSHCLQTGPSFHCLCLQGW-TGPLCNLPLSSCQK 888
T D C + +PCP SHC P+ W T PL L +
Sbjct: 1157 LTFDDCCCRQGRGWGAQCRPCPPRGAGSHC----PTSQSESNSFWDTSPLL---LGKPPR 1209
Query: 889 AALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ----GSLCQDHVNPCESRPCQNGAT 944
S D G CV C CP GFQ + C D ++ C Q G
Sbjct: 1210 DEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRARCVD-IDECRELN-QRGLL 1267
Query: 945 CMAQ-----PSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPK 986
C ++ + C C G+ +S+P HG C P+
Sbjct: 1268 CKSERCVNTSGSFRCVCKAGF-----------ARSRP---HGACVPQ 1300
Score = 184 bits (468), Expect = 6e-46
Identities = 252/994 (25%), Positives = 356/994 (35%), Gaps = 177/994 (17%)
Query: 302 CPETWTGWDCS--EDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDC 359
CP+ + + + +D++EC G CR+G C N+ GS+ CVC G S + C
Sbjct: 341 CPQGYKRLNSTHCQDINECAMPGV--CRHGD-CLNNPGSYRCVCPP---GHSLGPSRTQC 394
Query: 360 IAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGST--- 416
IA S C V P T L L C S A+C P G+
Sbjct: 395 IADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQL--CCCSVGKAWGARCQRCPTDGTAAFK 452
Query: 417 -LCLCQPGYSGPTCHQ--------DLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY 467
+C GY T HQ D L P P + S P + G
Sbjct: 453 EICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGV 512
Query: 468 TGSRCEADHNECLSQPCHPGSTCLDLLATFHCL---CPPGLEGQLCEV------------ 512
T ++ Q HP +T + PP + L ++
Sbjct: 513 TTDSPVSEERSV--QQSHPTATTTPARPYPELISRPSPPTMRWFLPDLPPSRSAVEIAPT 570
Query: 513 ---ETNEC-ASAPCLNHADCHDLLNGFQCICLPGFSG---TRCEEDIDECRSSPCANG-G 564
ET+EC + H +C + C C PG+ R D++EC + PC G G
Sbjct: 571 QVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRG 630
Query: 565 QCQDQPGAFHCKCLPGFE-----GPRCQTEVDECLSDP-CPVGASCLDLPGAFFCLCPSG 618
C + G+++C C G+ G R +++EC C G C++ PG + C C G
Sbjct: 631 ICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPG 690
Query: 619 FTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNC-TCHHGHCQRSSC 677
+ + P +C+ C+D CPDG P C C G+ +
Sbjct: 691 Y-----RLKASRPPVCEDIDECRDPSS-----CPDGKCENKPGSFKCIACQPGYRSQGGG 740
Query: 678 VC-DVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYT----GPTCSEEMTA 732
C DV EC +PC+ G C P + CTC GY G +C ++
Sbjct: 741 ACRDVN----ECAE------GSPCS-PGWCENLPGSFRCTCAQGYAPAPDGRSCL-DVDE 788
Query: 733 CHSGPCLNGGSCNPSPGGYYCTCPP----SHTGPQCQTSTDYCVSAPCFNGGTCVNRPGT 788
C +G + G C+ +PG + C C S C+ + A C GG C+N G+
Sbjct: 789 CEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACI-GGDCINTNGS 847
Query: 789 FSCLCAMGFQ---GPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYT----GGSC 841
+ CLC G + G +C+ S S C C++ C+C G+T C
Sbjct: 848 YRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGC 907
Query: 842 QTLMDLCAQKPCPRN--------SHCLQTGPSFHCLCL--QGWTGPLCNLPLSSCQKAAL 891
+ + +K C N S C C GW G C + +
Sbjct: 908 EEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGW-GDHCEI-----YPCPV 961
Query: 892 SQGIDVSSLCHNG-GLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPS 950
+ SLC +G G D+ + G D S C+ G QP
Sbjct: 962 YSSAEFHSLCPDGKGYTQDNNIVNY-----GIPAHRDIDECMLFGSEICKEGKCVNTQP- 1015
Query: 951 GYLCQCAPG--YDGQ--NCSKELDACQSQPCHNHGTCTPKPGGFHCACPP----GFVGLR 1002
GY C C G YDG C ++D C + +G C GG+ CAC P +
Sbjct: 1016 GYECYCKQGFYYDGNLLEC-VDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQ 1074
Query: 1003 C----EGDVDECLD-QPCHPTGTAACHSLANAFYCQC----LPGHTGQWCEVEIDP---- 1049
C E DVDEC D C P C +L ++ C+C +PG +G+ C++ P
Sbjct: 1075 CLSPEEMDVDECQDPAACRP---GRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERA 1131
Query: 1050 ------CHSQPCFHGGTCEATAGSPLGF-ICHCPKGFE-GPTCSHRAPSCGFHHC----- 1096
C SQ G AG L F C C +G G C P HC
Sbjct: 1132 PERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQS 1191
Query: 1097 HHGGLCLPSP-KPGFPPR-----------CACLSGY-----GGPDCLTPPAPKGCGPPSP 1139
SP G PPR C C+SG GG C P + +
Sbjct: 1192 ESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCVPRPGGAVCECPGGFQLDASRAR 1251
Query: 1140 CLYNGSCSETTGLGGPGFRCS---CPHSSPGPRC 1170
C+ C E L G C C ++S RC
Sbjct: 1252 CVDIDECRE---LNQRGLLCKSERCVNTSGSFRC 1282
Score = 155 bits (393), Expect = 3e-37
Identities = 178/672 (26%), Positives = 240/672 (35%), Gaps = 134/672 (19%)
Query: 32 PEPCANGGTCLSLSLGQGTCQCAPGFLGET-----CQFPDPCQNAQLC------------ 74
P C +GG C++ G C C PG+ + C+ D C++ C
Sbjct: 667 PHLCGDGGFCINFP-GHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSF 725
Query: 75 -----------QNGGSCQALLPAPLGLPSSPS---PLTPSFLCTCLPGFT----GERC-- 114
Q GG+C+ + G P SP L SF CTC G+ G C
Sbjct: 726 KCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLD 785
Query: 115 --QAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGW----TGEQCQLRDFCSANPCVNG 168
+ + D C CS G QC C+ G+ C+ D C G
Sbjct: 786 VDECEAGDVCDNGICSN-------TPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIG 838
Query: 169 GVCLATYPQIQCHCPPGFE---GHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG 225
G C+ T +C CP G G C+ D++EC QDP C +C N GS+ C+C G
Sbjct: 839 GDCINTNGSYRCLCPQGHRLVGGRKCQ-DIDECSQDPSLCLPHGACKNLQGSYVCVCDEG 897
Query: 226 ----QEGPRCELRAGPCPPRGC----SNGGTCQLMPEKDSTFHLCLCPPGF-IGPDCEVN 276
Q+ CE P + C + C + + T C C G G CE+
Sbjct: 898 FTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIY 957
Query: 277 PDNC-VSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNS 335
P C V + C DG YT G D+DEC G C+ G C N+
Sbjct: 958 P--CPVYSSAEFHSLCPDG-KGYTQDNNIVNYGIPAHRDIDECMLFGSEICKE-GKCVNT 1013
Query: 336 AGSFHCVCVSG--WGGTSCE-ENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHL 392
+ C C G + G E ++D+C+ + C + G + C C P
Sbjct: 1014 QPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTP--PAEYSPA 1071
Query: 393 EDMCLS------QPCHGDAQCSTN---PLTGSTLCLCQ----PGYSGPTCHQDLDECLMA 439
+ CLS C A C L GS C C+ PG SG C A
Sbjct: 1072 QRQCLSPEEMDVDECQDPAACRPGRCVNLPGSYRCECRPPWVPGPSGRDCQLPESPAERA 1131
Query: 440 QQGPSPC----EHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLA 495
+ C G C L P T C C P
Sbjct: 1132 PERRDVCWSQRGEDGMCAGP------LAGPALTFDDCCCRQGRGWGAQCRP--------- 1176
Query: 496 TFHCLCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDEC 555
CPP G C +E S D LL G P EED DEC
Sbjct: 1177 -----CPPRGAGSHCPTSQSESNS-----FWDTSPLLLG-----KPPRDEDSSEEDSDEC 1221
Query: 556 RSSPCANGGQCQDQPGAFHCKCLPGFE----GPRCQTEVDEC--LSDPCPVGAS--CLDL 607
R C + G+C +PG C+C GF+ RC ++DEC L+ + S C++
Sbjct: 1222 R---CVS-GRCVPRPGGAVCECPGGFQLDASRARC-VDIDECRELNQRGLLCKSERCVNT 1276
Query: 608 PGAFFCLCPSGF 619
G+F C+C +GF
Sbjct: 1277 SGSFRCVCKAGF 1288
Score = 152 bits (384), Expect = 3e-36
Identities = 189/725 (26%), Positives = 261/725 (36%), Gaps = 135/725 (18%)
Query: 551 DIDECRSSPCANG-GQCQDQPGAFHCKCLPGFEGP---RCQTEVDECLSDPCPVGAS-CL 605
+ DECR + G G+C P + C C PG+ R +V+EC ++PC G C+
Sbjct: 574 ETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRGICM 633
Query: 606 DLPGAFFCLCPSGFT------GQLC-EVPLCA-PNLCQPKQICKDQKDKANCLCPDGSPG 657
+ G++ C C G+ G+ C ++ CA P+LC C +
Sbjct: 634 NTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCIN--------------- 678
Query: 658 CAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNC-T 716
P C C+ G+ ++S P CE ++ C G C +P + C
Sbjct: 679 -FPGHYKCNCYPGYRLKAS-------RPPVCE-DIDECRDPSSCPDGKCENKPGSFKCIA 729
Query: 717 CPTGYT---GPTCSEEMTACHSGPCLNGGSCNPSPGGYYCTCP----PSHTGPQCQTSTD 769
C GY G C + PC + G C PG + CTC P+ G C D
Sbjct: 730 CQPGYRSQGGGACRDVNECAEGSPC-SPGWCENLPGSFRCTCAQGYAPAPDGRSC-LDVD 787
Query: 770 YCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEGKLRPSCAD-SPCRNRATCQ-----D 823
C + + G C N PG+F C C G+ R R C D C A C +
Sbjct: 788 ECEAGDVCDNGICSNTPGSFQCQCLSGYHLSRD----RSHCEDIDECDFPAACIGGDCIN 843
Query: 824 SPQGPRCLCPTGYT---GGSCQTLMDLCAQKP--CPRNSHCLQTGPSFHCLCLQGWTGPL 878
+ RCLCP G+ G CQ + D C+Q P C + C S+ C+C +G+T
Sbjct: 844 TNGSYRCLCPQGHRLVGGRKCQDI-DECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQ 902
Query: 879 ----CNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPC 934
C K D + C + + + C C G DH C
Sbjct: 903 DQHGCEEVEQPHHKKECYLNFDDTVFCDS--VLATNVTQQECCCSLGAGWG---DH---C 954
Query: 935 ESRPCQNGATCMAQPSGYLCQCAPGYDGQN--------CSKELDACQ---SQPCHNHGTC 983
E PC ++ LC GY N +++D C S+ C G C
Sbjct: 955 EIYPCPVYSSAEFHS---LCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEIC-KEGKC 1010
Query: 984 TPKPGGFHCACPPGFVG----LRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLP--- 1036
G+ C C GF L C DVDECLD+ G C + + C C P
Sbjct: 1011 VNTQPGYECYCKQGFYYDGNLLECV-DVDECLDESNCRNGV--CENTRGGYRCACTPPAE 1067
Query: 1037 -GHTGQWC----EVEIDPCHSQPCFHGGTCEATAGSPLGFICHC-PKGFEGPT---C--- 1084
+ C E+++D C G C GS + C C P GP+ C
Sbjct: 1068 YSPAQRQCLSPEEMDVDECQDPAACRPGRCVNLPGS---YRCECRPPWVPGPSGRDCQLP 1124
Query: 1085 ---SHRAPS----CGFHHCHHGGLCLPSPKPGFP-PRCACLSGYGGPDCLTPPAPKGCGP 1136
+ RAP C G P P C C G G P P+G G
Sbjct: 1125 ESPAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGS 1184
Query: 1137 PSPCLYNGSCS--ETTGL---GGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGC 1191
P + S S +T+ L P S S RC + C R G C+
Sbjct: 1185 HCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCV---SGRCVPRPGGAVCEC-- 1239
Query: 1192 SGPGG 1196
PGG
Sbjct: 1240 --PGG 1242
Score = 150 bits (379), Expect = 1e-35
Identities = 176/674 (26%), Positives = 232/674 (34%), Gaps = 149/674 (22%)
Query: 636 PKQICKDQKDKANC-LCPDGSPGCAPPEDNCTCHHG---HCQRSSCVCDVGWTGPECEAE 691
P Q+ + + + N +C G PP+ +C C+ G H Q CV DV ECEAE
Sbjct: 569 PTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCV-DVN----ECEAE 623
Query: 692 LGGCISAPCAHG-GTCYPQPSGYNCTCPTGYT------GPTCSEEMTACHSGPCLNGGSC 744
PC G G C YNC C GY G +C + C +GG C
Sbjct: 624 -------PCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFC 676
Query: 745 NPSPGGYYCTCPPSHT-----GPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCL-CAMGFQ 798
PG Y C C P + P C+ D C G C N+PG+F C+ C G++
Sbjct: 677 INFPGHYKCNCYPGYRLKASRPPVCE-DIDECRDPSSCPDGKCENKPGSFKCIACQPGYR 735
Query: 799 ---GPRCEGKLRPSCAD-SPCRNRATCQDSPQGPRCLCPTGYT----GGSCQTLMDLCAQ 850
G C CA+ SPC + C++ P RC C GY G SC + + A
Sbjct: 736 SQGGGACRDV--NECAEGSPC-SPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAG 792
Query: 851 KPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDS 910
C N C T SF C CL G+ + S C+ D + C GG C+++
Sbjct: 793 DVCD-NGICSNTPGSFQCQCLSGYH---LSRDRSHCEDI---DECDFPAACI-GGDCINT 844
Query: 911 GPSYFCHCPPGFQ---GSLCQDHVNPCESRP--CQNGATCMAQPSGYLCQCAPGY----D 961
SY C CP G + G CQD ++ C P C C Y+C C G+ D
Sbjct: 845 NGSYRCLCPQGHRLVGGRKCQD-IDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQD 903
Query: 962 GQNCSKELDACQSQPCH-------------------------------NHGTCTPKP--- 987
C + + C+ +H P P
Sbjct: 904 QHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYS 963
Query: 988 -GGFHCACPPGF----------VGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLP 1036
FH CP G G+ D+DEC+ C + + C C
Sbjct: 964 SAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQ 1023
Query: 1037 G--HTGQWCE-VEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPS--- 1090
G + G E V++D C + G CE T G G+ C C E + S
Sbjct: 1024 GFYYDGNLLECVDVDECLDESNCRNGVCENTRG---GYRCACTPPAEYSPAQRQCLSPEE 1080
Query: 1091 CGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETT 1150
C C P RC L G +C P P
Sbjct: 1081 MDVDECQDPAACRPG-------RCVNLPGSYRCECRPPWVP------------------- 1114
Query: 1151 GLGGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGPGGNWDGGDCSLG---- 1206
G G C P S P R + R DG C +GP +D C G
Sbjct: 1115 --GPSGRDCQLPES-PAERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWG 1171
Query: 1207 ---VPDPWKGCPSH 1217
P P +G SH
Sbjct: 1172 AQCRPCPPRGAGSH 1185
Score = 107 bits (266), Expect = 2e-22
Identities = 115/394 (29%), Positives = 146/394 (37%), Gaps = 88/394 (22%)
Query: 905 GLCVDSGPSYFCHCPPGF----QGSLCQDHVNPCESRPCQNG-ATCMAQPSGYLCQCAPG 959
G CV P Y CHC PG+ Q C D VN CE+ PC G CM Y C C G
Sbjct: 588 GECVPGPPDYSCHCNPGYRSHPQHRYCVD-VNECEAEPCGPGRGICMNTGGSYNCHCNRG 646
Query: 960 Y------DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLR------CEGDV 1007
Y G++C + + C + G C PG + C C PG+ L+ CE D+
Sbjct: 647 YRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGY-RLKASRPPVCE-DI 704
Query: 1008 DECLDQPCHPTGTAACHSLANAFYC-QCLPGHTGQW---CEVEIDPCHSQPCFHGGTCEA 1063
DEC D P G C + +F C C PG+ Q C + PC G CE
Sbjct: 705 DECRDPSSCPDGK--CENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPC-SPGWCEN 761
Query: 1064 TAGSPLGFICHCPKGFEGPTCSHRAPSC-GFHHCHHGGLC---LPSPKPGFPPRCACLSG 1119
GS F C C +G+ P R SC C G +C + S PG +C CLSG
Sbjct: 762 LPGS---FRCTCAQGY-APAPDGR--SCLDVDECEAGDVCDNGICSNTPG-SFQCQCLSG 814
Query: 1120 YG-GPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGC 1178
Y D C P+ C+ G C T G +RC CP + G + C
Sbjct: 815 YHLSRDRSHCEDIDECDFPAACI-GGDCINTNG----SYRCLCPQGH-----RLVGGRKC 864
Query: 1179 EGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEEC 1238
+ D +CS DP C H C +
Sbjct: 865 Q-------------------DIDECS---QDP-SLCLPHGAC----------------KN 885
Query: 1239 LFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGC 1272
L Y C TP DQ+ + H +K C
Sbjct: 886 LQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKEC 919
Score = 82.0 bits (201), Expect = 5e-15
Identities = 149/586 (25%), Positives = 202/586 (34%), Gaps = 121/586 (20%)
Query: 686 PECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTA-----CHSGPCLN 740
P + LG C T QP G N C TA CH P L
Sbjct: 270 PPTQKPLGRCFQ------DTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQ 323
Query: 741 -GGSCNPSP--GGYYCTCPPSH---TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCA 794
G P P G CP + CQ + + C +G C+N PG++ C+C
Sbjct: 324 YTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECAMPGVCRHGD-CLNNPGSYRCVCP 382
Query: 795 MGFQGPRCEGKLRPSC-ADSP-----CRNRATCQDSPQGP--------RCLCPTGYTGGS 840
G G R C AD P C + + Q P C C G G+
Sbjct: 383 PG----HSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGA 438
Query: 841 ----CQTLMDLCAQKPCP--RNSHCLQTGPSFHCLCLQGWT---------GPLCNLPLSS 885
C T ++ CP + H L S L +QG + GP P
Sbjct: 439 RCQRCPTDGTAAFKEICPAGKGYHIL---TSHQTLTIQGESDFSLFLHPDGP----PKPQ 491
Query: 886 CQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATC 945
+ SQ G+ DS P + S+ Q H + P +
Sbjct: 492 QLPESPSQAPPPEDTEEERGVTTDS--------PVSEERSVQQSHPT-ATTTPARPYPEL 542
Query: 946 MAQPS-----GYLCQCAPGYDGQNCS----KELDACQ-SQPCHNHGTCTPKPGGFHCACP 995
+++PS +L P + E D C+ +Q HG C P P + C C
Sbjct: 543 ISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCN 602
Query: 996 PGFVG---LRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT------GQWCEVE 1046
PG+ R DV+EC +PC P G C + ++ C C G+ G+ C V+
Sbjct: 603 PGYRSHPQHRYCVDVNECEAEPCGP-GRGICMNTGGSYNCHCNRGYRLHVGAGGRSC-VD 660
Query: 1047 IDPCHSQP--CFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSC-GFHHCHHGGLCL 1103
++ C ++P C GG C P + C+C G+ + R P C C C
Sbjct: 661 LNEC-AKPHLCGDGGFC---INFPGHYKCNCYPGYR--LKASRPPVCEDIDECRDPSSCP 714
Query: 1104 PSP---KPGFPPRCACLSGY---GGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGF 1157
KPG AC GY GG C C SPC G C G F
Sbjct: 715 DGKCENKPGSFKCIACQPGYRSQGGGACRD---VNECAEGSPC-SPGWCENLPG----SF 766
Query: 1158 RCSCPHSSPGPRCQKPGAKGC----EGRSGDGACDAG-CSGPGGNW 1198
RC+C P + C E +GD CD G CS G++
Sbjct: 767 RCTCAQG----YAPAPDGRSCLDVDECEAGD-VCDNGICSNTPGSF 807
Score = 58.2 bits (139), Expect = 8e-08
Identities = 39/117 (33%), Positives = 52/117 (44%), Gaps = 13/117 (11%)
Query: 411 PLTGSTLCLCQPGYS--GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT 468
P+ G C GY T QD++EC M P C HG CLN PGS+ C+CPPG++
Sbjct: 332 PVRGEVGADCPQGYKRLNSTHCQDINECAM----PGVCRHG-DCLNNPGSYRCVCPPGHS 386
Query: 469 GSRCEADHNECLSQPCHPGSTCLDLLATFH-CLCP--PGLEGQLCEVETNECASAPC 522
+C++ S C L++ H C P L QLC + A C
Sbjct: 387 ---LGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARC 440
Score = 42.7 bits (99), Expect = 0.004
Identities = 79/333 (23%), Positives = 109/333 (32%), Gaps = 56/333 (16%)
Query: 205 CPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGP------CPPRGCSNGGTCQLMPEKDST 258
C KG C ++ + +G+ G + G CP C NGG C S+
Sbjct: 75 CLKG-QCRDSCQQGSNMTLIGENGHSTDTLTGSGFRVVVCP-LPCMNGGQC-------SS 125
Query: 259 FHLCLCPPGFIGPDCEVNPDNCVSHQCQNG-GTCQDGLDTYTCLCPETWTGWDCSEDVDE 317
+ CLCPP F G C+V +G G + G + L P G +
Sbjct: 126 RNQCLCPPDFTGRFCQVPAGGAGGGTGGSGPGLSRTGALSTGALPPLAPEGDSVASKHAI 185
Query: 318 CETQ---GPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCA----PGSTC 370
Q PP G Q++A + G G S E + S
Sbjct: 186 YAVQVIADPPGPGEGPPAQHAA----FLVPLGPGQISAEVQAPPPVVNVRVHHPPEASVQ 241
Query: 371 IDRVGSFSCLCPPGRTGLLCHLEDMCLSQP-------CHGDA----QCSTNPLTGSTL-- 417
+ R+ S + LL H + P C D C +NPL G T
Sbjct: 242 VHRIESSNAESAAPSQHLLPHPKPSHPRPPTQKPLGRCFQDTLPKQPCGSNPLPGLTKQE 301
Query: 418 -CLCQPG--YSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY---TGSR 471
C G + CH+ Q P P G CP GY +
Sbjct: 302 DCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVR---------GEVGADCPQGYKRLNSTH 352
Query: 472 CEADHNECLSQPCHPGSTCLDLLATFHCLCPPG 504
C+ D NEC CL+ ++ C+CPPG
Sbjct: 353 CQ-DINECAMPGVCRHGDCLNNPGSYRCVCPPG 384
Score = 42.7 bits (99), Expect = 0.004
Identities = 93/378 (24%), Positives = 119/378 (31%), Gaps = 72/378 (19%)
Query: 164 PCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCP 223
PC+NGG C + + QC CPP F G C+ G G S L S L P
Sbjct: 116 PCMNGGQCSS---RNQCLCPPDFTGRFCQVPAGGAGGGTGGSGPGLSRTGAL-STGALPP 171
Query: 224 VGQEGPRCELRAG----------PCPPRGCSNGGTCQLMPEKDSTFHL-CLCPPGFIG-- 270
+ EG + P P G L+P PP +
Sbjct: 172 LAPEGDSVASKHAIYAVQVIADPPGPGEGPPAQHAAFLVPLGPGQISAEVQAPPPVVNVR 231
Query: 271 ----PDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTG---WDCSEDV---DECET 320
P+ V S ++ Q L P T C +D C +
Sbjct: 232 VHHPPEASVQVHRIESSNAESAAPSQHLLPHPKPSHPRPPTQKPLGRCFQDTLPKQPCGS 291
Query: 321 QGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCL 380
P C S G + WG + C + PG G
Sbjct: 292 NPLPGLTKQEDCCGSIG-------TAWGQSKCHKCPQLQYTGVQKPGPV----RGEVGAD 340
Query: 381 CPPGRTGL-LCHLEDM---CLSQPC-HGDAQCSTNPLTGSTLCLCQPGYS-GPT---CHQ 431
CP G L H +D+ + C HGD C NP GS C+C PG+S GP+ C
Sbjct: 341 CPQGYKRLNSTHCQDINECAMPGVCRHGD--CLNNP--GSYRCVCPPGHSLGPSRTQCIA 396
Query: 432 DLDE----CLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT-GSRCEADHNECLSQPCHP 486
D E C C+H + T C C G G+RC Q C
Sbjct: 397 DKPEEKSLCFRLVSPEHQCQHPLTTRLTRQL--CCCSVGKAWGARC---------QRCPT 445
Query: 487 GSTCLDLLATFHCLCPPG 504
T A F +CP G
Sbjct: 446 DGT-----AAFKEICPAG 458
Score = 42.7 bits (99), Expect = 0.004
Identities = 73/298 (24%), Positives = 96/298 (32%), Gaps = 66/298 (22%)
Query: 737 PCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMG 796
PC+NGG C+ C CPP TG CQ V A GGT + PG +
Sbjct: 116 PCMNGGQCSSRN---QCLCPPDFTGRFCQ------VPAGGAGGGTGGSGPG-------LS 159
Query: 797 FQGPRCEGKLRP------SCADSPCRNRATCQDSPQGPRCLCPTGYTG-----GSCQTLM 845
G G L P S A P GP P + G Q
Sbjct: 160 RTGALSTGALPPLAPEGDSVASKHAIYAVQVIADPPGPGEGPPAQHAAFLVPLGPGQISA 219
Query: 846 DLCAQKPCP-----------------RNSHCLQTGPSFHCL--CLQGWTGPLCNLPLSSC 886
++ A P +S+ PS H L P PL C
Sbjct: 220 EVQAPPPVVNVRVHHPPEASVQVHRIESSNAESAAPSQHLLPHPKPSHPRPPTQKPLGRC 279
Query: 887 QKAALSQ----GIDVSSLCHNGGLCVDSGPSY---FCHCPPGFQGSLCQDHVNPCESRPC 939
+ L + + L C G ++ CH P Q + Q P R
Sbjct: 280 FQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQ---KPGPVRG- 335
Query: 940 QNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPG 997
+ GA C P GY + +C ++++ C HG C PG + C CPPG
Sbjct: 336 EVGADC---PQGY-----KRLNSTHC-QDINECAMPGVCRHGDCLNNPGSYRCVCPPG 384
Score = 37.7 bits (86), Expect = 0.11
Identities = 92/407 (22%), Positives = 132/407 (32%), Gaps = 70/407 (17%)
Query: 6 LLLLLLLLLLLCVSVVRPRGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETC--- 62
L LLLLLLLLL R G G E A GG L+ + AP TC
Sbjct: 24 LALLLLLLLLLLGLGGRVEG---GPAGERGAGGGGALARE--RFKVVFAPVICKRTCLKG 78
Query: 63 QFPDPCQNAQ----LCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKL 118
Q D CQ + +NG S L + + P LP G +C ++
Sbjct: 79 QCRDSCQQGSNMTLIGENGHSTDTLTGSGFRVVVCP-----------LPCMNGGQCSSRN 127
Query: 119 EDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVN--GGVCLATYP 176
+ CPP F + C + A G G TG + P ++ G + P
Sbjct: 128 QCLCPPDFTGR--FCQVPAGG------AGGGTG---------GSGPGLSRTGALSTGALP 170
Query: 177 QIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAG 236
+ HA V PGP + H L P+G E++A
Sbjct: 171 PLAPEGDSVASKHAIYA-VQVIADPPGPGEGPPAQHAAF-----LVPLGPGQISAEVQAP 224
Query: 237 P--------CPPRGCSNGGTCQLMPEKDSTFHLCLCP---PGFIGPDCEVNPDNCVSHQC 285
P PP + + + L P P P + C
Sbjct: 225 PPVVNVRVHHPPEASVQVHRIESSNAESAAPSQHLLPHPKPSHPRPPTQKPLGRCFQDTL 284
Query: 286 QN---GGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCV 342
G GL C T W S+ +C + G + G+
Sbjct: 285 PKQPCGSNPLPGLTKQEDCCGSIGTAWGQSK-CHKCPQLQYTGVQKPGPVRGEVGA---D 340
Query: 343 CVSGW---GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRT 386
C G+ T C++ + + C G C++ GS+ C+CPPG +
Sbjct: 341 CPQGYKRLNSTHCQDINECAMPGVCRHGD-CLNNPGSYRCVCPPGHS 386
Score = 35.8 bits (81), Expect = 0.43
Identities = 22/61 (36%), Positives = 24/61 (39%), Gaps = 9/61 (14%)
Query: 1137 PSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKP--GAKGCEGRSGDGACDAGCSGP 1194
P PC+ G CS +C CP G CQ P GA G G SG G G
Sbjct: 114 PLPCMNGGQCSSRN-------QCLCPPDFTGRFCQVPAGGAGGGTGGSGPGLSRTGALST 166
Query: 1195 G 1195
G
Sbjct: 167 G 167
Score = 32.0 bits (71), Expect = 6.2
Identities = 14/31 (45%), Positives = 16/31 (51%), Gaps = 3/31 (9%)
Query: 597 PCPVGASCLDLPGAFFCLCPSGFTGQLCEVP 627
PC G C CLCP FTG+ C+VP
Sbjct: 116 PCMNGGQCSSRNQ---CLCPPDFTGRFCQVP 143
Score = 32.0 bits (71), Expect = 6.2
Identities = 14/29 (48%), Positives = 15/29 (51%), Gaps = 3/29 (10%)
Query: 559 PCANGGQCQDQPGAFHCKCLPGFEGPRCQ 587
PC NGGQC + C C P F G CQ
Sbjct: 116 PCMNGGQCSSRN---QCLCPPDFTGRFCQ 141
Score = 31.6 bits (70), Expect = 8.2
Identities = 27/93 (29%), Positives = 37/93 (39%), Gaps = 18/93 (19%)
Query: 666 TCHHGHC----QRSSCVCDVGWTGPECEAELGGCISA-----PCAHGGTCYPQPSGYNCT 716
TC G C Q+ S + +G G + G PC +GG C S C
Sbjct: 74 TCLKGQCRDSCQQGSNMTLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQC---SSRNQCL 130
Query: 717 CPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPG 749
CP +TG C ++ A +G GG+ PG
Sbjct: 131 CPPDFTGRFC--QVPAGGAG----GGTGGSGPG 157
Score = 31.6 bits (70), Expect = 8.2
Identities = 18/71 (25%), Positives = 26/71 (36%), Gaps = 11/71 (15%)
Query: 656 PGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNC 715
PG E C G+ + +S C ++ C G C P Y C
Sbjct: 330 PGPVRGEVGADCPQGYKRLNSTHCQ----------DINECAMPGVCRHGDCLNNPGSYRC 379
Query: 716 TCPTGYT-GPT 725
CP G++ GP+
Sbjct: 380 VCPPGHSLGPS 390
>gi|18497288 latent transforming growth factor beta binding protein 3
isoform 2 [Homo sapiens]
Length = 1256
Score = 202 bits (514), Expect = 3e-51
Identities = 213/733 (29%), Positives = 281/733 (38%), Gaps = 138/733 (18%)
Query: 158 DFCSANPCVNG-GVCLATYPQIQCHCPPGFEGHACER---DVNECFQDPGPCPKGTS-CH 212
D C N + G G C+ P CHC PG+ H R DVNEC + PC G C
Sbjct: 576 DECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNEC--EAEPCGPGRGICM 633
Query: 213 NTLGSFQCLC------PVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPP 266
NT GS+ C C VG G C P C +GG C P + C C P
Sbjct: 634 NTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFP----GHYKCNCYP 689
Query: 267 GF-----IGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETW---TGWDCSEDVDEC 318
G+ P CE + D C G C++ ++ C+ + G DV+EC
Sbjct: 690 GYRLKASRPPVCE-DIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNEC 748
Query: 319 ETQGPPHCRNGGTCQNSAGSFHCVCVSGWG----GTSCEENLDDCIAATCAPGSTCIDRV 374
P C + G C+N GSF C C G+ G SC + +D+C A C +
Sbjct: 749 AEGSP--C-SPGWCENLPGSFRCTCAQGYAPAPDGRSCLD-VDECEAGDVCDNGICSNTP 804
Query: 375 GSFSCLCPPG----RTGLLCHLEDMC-LSQPCHGDAQCSTNPLTGSTLCLCQPGY---SG 426
GSF C C G R C D C C G +TN GS CLC G+ G
Sbjct: 805 GSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTN---GSYRCLCPQGHRLVGG 861
Query: 427 PTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNEC--LSQPC 484
C QD+DEC Q PS C G+C N GS+ C+C G+T ++ D + C + QP
Sbjct: 862 RKC-QDIDEC---SQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQ---DQHGCEEVEQPH 914
Query: 485 HPGST---------CLDLLAT----FHCLCPPGLE-GQLCEVETNECASAPCLNHADCHD 530
H C +LAT C C G G CE+ P + A+ H
Sbjct: 915 HKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEI-----YPCPVYSSAEFHS 969
Query: 531 LLNGFQCICLPGFS--------GTRCEEDIDECR---SSPCANGGQCQDQPGAFHCKCLP 579
L C G++ G DIDEC S C G QPG + C C
Sbjct: 970 L-----CPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPG-YECYCKQ 1023
Query: 580 GF--EGPRCQ-TEVDECLSDPCPVGASCLDLPGAFFCLC--PSGFT--GQLCEVPLCAPN 632
GF +G + +VDECL + C + G + C C P+ ++ + C P
Sbjct: 1024 GFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMER 1083
Query: 633 LCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAEL 692
+ + +C Q+ + + +C G A D+C C G GW G +C
Sbjct: 1084 APERRDVCWSQRGE-DGMCAGPLAGPALTFDDCCCRQGR----------GW-GAQCR--- 1128
Query: 693 GGCISAPC------AHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTACHSGPC-LNGGSCN 745
PC +H T + + + T P P E+ + S C G C
Sbjct: 1129 ------PCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCVSGRCV 1182
Query: 746 PSPGGYYCTCPPSHTGPQCQTSTDYCVSAP----------CFNGGTCVNRPGTFSCLCAM 795
P PGG C CP G Q S CV CVN G+F C+C
Sbjct: 1183 PRPGGAVCECP---GGFQLDASRARCVDIDECRELNQRGLLCKSERCVNTSGSFRCVCKA 1239
Query: 796 GFQGPRCEGKLRP 808
GF R G P
Sbjct: 1240 GFARSRPHGACVP 1252
Score = 192 bits (489), Expect = 2e-48
Identities = 201/735 (27%), Positives = 278/735 (37%), Gaps = 121/735 (16%)
Query: 352 CEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTG----LLCHLEDMCLSQPCHGDAQC 407
C N + C C PG +SC C PG C + C ++PC G +
Sbjct: 578 CRLNQNICGHGECVPGPP------DYSCHCNPGYRSHPQHRYCVDVNECEAEPC-GPGRG 630
Query: 408 STNPLTGSTLCLCQPGY------SGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNC 461
GS C C GY G +C DL+EC P C GG C+N PG + C
Sbjct: 631 ICMNTGGSYNCHCNRGYRLHVGAGGRSC-VDLNECAK----PHLCGDGGFCINFPGHYKC 685
Query: 462 LCPPGYT--GSR---CEADHNECLSQPCHPGSTCLDLLATFHCL-CPPGLEGQ---LCEV 512
C PGY SR CE D +EC P C + +F C+ C PG Q C
Sbjct: 686 NCYPGYRLKASRPPVCE-DIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACR- 743
Query: 513 ETNECASAPCLNHADCHDLLNGFQCICLPGFS----GTRCEEDIDECRSSPCANGGQCQD 568
+ NECA + C +L F+C C G++ G C D+DEC + + G C +
Sbjct: 744 DVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCL-DVDECEAGDVCDNGICSN 802
Query: 569 QPGAFHCKCLPGFEGPRCQT---EVDECLSDPCPVGASCLDLPGAFFCLCPSGFT---GQ 622
PG+F C+CL G+ R ++ ++DEC +G C++ G++ CLCP G G+
Sbjct: 803 TPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIGGDCINTNGSYRCLCPQGHRLVGGR 862
Query: 623 LC-EVPLCA--PNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCVC 679
C ++ C+ P+LC P CK+ + C+C + G P +D C C
Sbjct: 863 KCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDE---GFTPTQDQHGCEEVEQPHHKKEC 919
Query: 680 DVGWTGPE-CEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGY-TGPTCSEEMTACHSGP 737
+ + C++ L ++ C C G G C E+ C
Sbjct: 920 YLNFDDTVFCDSVLATNVTQ--------------QECCCSLGAGWGDHC--EIYPCPVYS 963
Query: 738 CLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCV---SAPCFNGGTCVNRPGTFSCLCA 794
S P GY + G D C+ S C G CVN + C C
Sbjct: 964 SAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEG-KCVNTQPGYECYCK 1022
Query: 795 MGF--QGPRCEGKLRPSCAD-SPCRNRATCQDSPQGPRCLC--PTGYTGGSCQTLMDLCA 849
GF G E C D S CRN C+++ G RC C P Y+ Q L
Sbjct: 1023 QGFYYDGNLLECVDVDECLDESNCRN-GVCENTRGGYRCACTPPAEYSPAQRQCLSPEEM 1081
Query: 850 QKPCPRNSHC-LQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCV 908
++ R C Q G C GPL P + QG + C
Sbjct: 1082 ERAPERRDVCWSQRGEDGMC------AGPLAG-PALTFDDCCCRQGRGWGAQCR------ 1128
Query: 909 DSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKE 968
CPP GS C P + + L P D + ++
Sbjct: 1129 --------PCPPRGAGSHC----------PTSQSESNSFWDTSPLLLGKPPRDEDSSEED 1170
Query: 969 LDACQSQPCHNHGTCTPKPGGFHCACPPGF----VGLRCEGDVDEC--LDQPCHPTGTAA 1022
D C+ G C P+PGG C CP GF RC D+DEC L+Q +
Sbjct: 1171 SDECRCV----SGRCVPRPGGAVCECPGGFQLDASRARCV-DIDECRELNQRGLLCKSER 1225
Query: 1023 CHSLANAFYCQCLPG 1037
C + + +F C C G
Sbjct: 1226 CVNTSGSFRCVCKAG 1240
Score = 166 bits (420), Expect = 2e-40
Identities = 219/915 (23%), Positives = 319/915 (34%), Gaps = 194/915 (21%)
Query: 302 CPETWTGWDCS--EDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDC 359
CP+ + + + +D++EC G CR+G C N+ GS+ CVC G S + C
Sbjct: 341 CPQGYKRLNSTHCQDINECAMPGV--CRHGD-CLNNPGSYRCVCPP---GHSLGPSRTQC 394
Query: 360 IAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHLEDMCLSQPCHGDAQCSTNPLTGST--- 416
IA S C V P T L L C S A+C P G+
Sbjct: 395 IADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQL--CCCSVGKAWGARCQRCPTDGTAAFK 452
Query: 417 -LCLCQPGYSGPTCHQ--------DLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY 467
+C GY T HQ D L P P + S P + G
Sbjct: 453 EICPAGKGYHILTSHQTLTIQGESDFSLFLHPDGPPKPQQLPESPSQAPPPEDTEEERGV 512
Query: 468 TGSRCEADHNECLSQPCHPGSTCLDLLATFHCL---CPPGLEGQLCEV------------ 512
T ++ Q HP +T + PP + L ++
Sbjct: 513 TTDSPVSEERSV--QQSHPTATTTPARPYPELISRPSPPTMRWFLPDLPPSRSAVEIAPT 570
Query: 513 ---ETNEC-ASAPCLNHADCHDLLNGFQCICLPGFSG---TRCEEDIDECRSSPCANG-G 564
ET+EC + H +C + C C PG+ R D++EC + PC G G
Sbjct: 571 QVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCVDVNECEAEPCGPGRG 630
Query: 565 QCQDQPGAFHCKCLPGFE-----GPRCQTEVDECLSDP-CPVGASCLDLPGAFFCLCPSG 618
C + G+++C C G+ G R +++EC C G C++ PG + C C G
Sbjct: 631 ICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPG 690
Query: 619 FTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNC-TCHHGHCQRSSC 677
+ + P +C+ C+D CPDG P C C G+ +
Sbjct: 691 Y-----RLKASRPPVCEDIDECRDPSS-----CPDGKCENKPGSFKCIACQPGYRSQGGG 740
Query: 678 VC-DVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYT----GPTCSEEMTA 732
C DV EC +PC+ G C P + CTC GY G +C ++
Sbjct: 741 ACRDVN----ECAE------GSPCS-PGWCENLPGSFRCTCAQGYAPAPDGRSCL-DVDE 788
Query: 733 CHSGPCLNGGSCNPSPGGYYCTCPP----SHTGPQCQTSTDYCVSAPCFNGGTCVNRPGT 788
C +G + G C+ +PG + C C S C+ + A C GG C+N G+
Sbjct: 789 CEAGDVCDNGICSNTPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACI-GGDCINTNGS 847
Query: 789 FSCLCAMGFQ---GPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQ--- 842
+ CLC G + G +C+ S S C C++ C+C G+T Q
Sbjct: 848 YRCLCPQGHRLVGGRKCQDIDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGC 907
Query: 843 ------------------------------TLMDLCAQKPCPRNSHC------LQTGPSF 866
T + C HC + + F
Sbjct: 908 EEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEF 967
Query: 867 HCLCL--QGWT--------GPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFC 916
H LC +G+T G + + C + S +C G CV++ P Y C
Sbjct: 968 HSLCPDGKGYTQDNNIVNYGIPAHRDIDECM-------LFGSEICKE-GKCVNTQPGYEC 1019
Query: 917 HCPPGF--QGSL--CQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKEL--- 969
+C GF G+L C D + C+NG C GY C C P + ++
Sbjct: 1020 YCKQGFYYDGNLLECVDVDECLDESNCRNG-VCENTRGGYRCACTPPAEYSPAQRQCLSP 1078
Query: 970 ----------DACQSQPCHNHGTCTPKPGG-----FHCACPPGFVGLRCEGDVDECLDQP 1014
D C SQ + G C G C C G G +C +P
Sbjct: 1079 EEMERAPERRDVCWSQRGED-GMCAGPLAGPALTFDDCCCRQG------RGWGAQC--RP 1129
Query: 1015 CHPTGTAA----CHSLANAFYCQC-----LPGHTGQWCEVEIDPCHSQPCFHGGTCEATA 1065
C P G + S +N+F+ P E + D C G C
Sbjct: 1130 CPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCV----SGRCVPRP 1185
Query: 1066 GSPLGFICHCPKGFE 1080
G G +C CP GF+
Sbjct: 1186 G---GAVCECPGGFQ 1197
Score = 162 bits (409), Expect = 4e-39
Identities = 182/687 (26%), Positives = 262/687 (38%), Gaps = 200/687 (29%)
Query: 96 PLTPSFLCTCLPGFTGE----------RCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSC 145
P P + C C PG+ C+A +PC P RG C + G C C
Sbjct: 592 PGPPDYSCHCNPGYRSHPQHRYCVDVNECEA---EPCGPG----RGIC-MNTGGSYNCHC 643
Query: 146 MPGWT------GEQC-QLRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHA-----CER 193
G+ G C L + + C +GG C+ +C+C PG+ A CE
Sbjct: 644 NRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGYRLKASRPPVCE- 702
Query: 194 DVNECFQDPGPCPKGTSCHNTLGSFQCL-CPVG---QEGPRCE-----LRAGPCPPRGCS 244
D++EC +DP CP G C N GSF+C+ C G Q G C PC P
Sbjct: 703 DIDEC-RDPSSCPDG-KCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCSP---- 756
Query: 245 NGGTCQLMPEKDSTFHLCLCPPGFI----GPDCEVNPDNCVSHQCQNGGTCQDGLDTYTC 300
G C+ +P +F C C G+ G C ++ D C + + G C + ++ C
Sbjct: 757 --GWCENLP---GSFR-CTCAQGYAPAPDGRSC-LDVDECEAGDVCDNGICSNTPGSFQC 809
Query: 301 LCPETWTGWDCS------EDVDECETQGPPHCRNGGTCQNSAGSFHCVCVSGW---GGTS 351
C +G+ S ED+DEC+ P GG C N+ GS+ C+C G GG
Sbjct: 810 QC---LSGYHLSRDRSHCEDIDECDF---PAACIGGDCINTNGSYRCLCPQGHRLVGGRK 863
Query: 352 CEENLDDCI--AATCAPGSTCIDRVGSFSCLCPPGRTGLL----------------CHL- 392
C++ +D+C + C P C + GS+ C+C G T C+L
Sbjct: 864 CQD-IDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKECYLN 922
Query: 393 -----------------EDMCLSQPCHGDAQCSTNP------LTGSTLCLCQPGYS---- 425
++ C S C P +LC GY+
Sbjct: 923 FDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYSSAEFHSLCPDGKGYTQDNN 982
Query: 426 ----GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPG--YTGSRCE-ADHNE 478
G H+D+DEC++ G C+ G C+NT + C C G Y G+ E D +E
Sbjct: 983 IVNYGIPAHRDIDECMLF--GSEICKE-GKCVNTQPGYECYCKQGFYYDGNLLECVDVDE 1039
Query: 479 CLSQPCHPGSTCLDLLATFHCLCPPGLE--------------------GQLCEVETNE-- 516
CL + C + + C C P E +C + E
Sbjct: 1040 CLDESNCRNGVCENTRGGYRCACTPPAEYSPAQRQCLSPEEMERAPERRDVCWSQRGEDG 1099
Query: 517 -CA---SAPCLNHADCHDLLN---GFQC-ICLPGFSGTRC-------------------- 548
CA + P L DC G QC C P +G+ C
Sbjct: 1100 MCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGK 1159
Query: 549 --------EEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE----GPRCQTEVDEC--L 594
EED DECR C + G+C +PG C+C GF+ RC ++DEC L
Sbjct: 1160 PPRDEDSSEEDSDECR---CVS-GRCVPRPGGAVCECPGGFQLDASRARC-VDIDECREL 1214
Query: 595 SDPCPVGAS--CLDLPGAFFCLCPSGF 619
+ + S C++ G+F C+C +GF
Sbjct: 1215 NQRGLLCKSERCVNTSGSFRCVCKAGF 1241
Score = 147 bits (370), Expect = 1e-34
Identities = 177/662 (26%), Positives = 233/662 (35%), Gaps = 136/662 (20%)
Query: 636 PKQICKDQKDKANC-LCPDGSPGCAPPEDNCTCHHG---HCQRSSCVCDVGWTGPECEAE 691
P Q+ + + + N +C G PP+ +C C+ G H Q CV DV ECEAE
Sbjct: 569 PTQVTETDECRLNQNICGHGECVPGPPDYSCHCNPGYRSHPQHRYCV-DVN----ECEAE 623
Query: 692 LGGCISAPCAHG-GTCYPQPSGYNCTCPTGYT------GPTCSEEMTACHSGPCLNGGSC 744
PC G G C YNC C GY G +C + C +GG C
Sbjct: 624 -------PCGPGRGICMNTGGSYNCHCNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFC 676
Query: 745 NPSPGGYYCTCPPSHT-----GPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCL-CAMGFQ 798
PG Y C C P + P C+ D C G C N+PG+F C+ C G++
Sbjct: 677 INFPGHYKCNCYPGYRLKASRPPVCE-DIDECRDPSSCPDGKCENKPGSFKCIACQPGYR 735
Query: 799 ---GPRCEGKLRPSCAD-SPCRNRATCQDSPQGPRCLCPTGYT----GGSCQTLMDLCAQ 850
G C CA+ SPC + C++ P RC C GY G SC + + A
Sbjct: 736 SQGGGACRDV--NECAEGSPC-SPGWCENLPGSFRCTCAQGYAPAPDGRSCLDVDECEAG 792
Query: 851 KPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDS 910
C N C T SF C CL G+ + S C+ D + C GG C+++
Sbjct: 793 DVCD-NGICSNTPGSFQCQCLSGYH---LSRDRSHCEDI---DECDFPAACI-GGDCINT 844
Query: 911 GPSYFCHCPPGFQ---GSLCQDHVNPCESRP--CQNGATCMAQPSGYLCQCAPGY----D 961
SY C CP G + G CQD ++ C P C C Y+C C G+ D
Sbjct: 845 NGSYRCLCPQGHRLVGGRKCQD-IDECSQDPSLCLPHGACKNLQGSYVCVCDEGFTPTQD 903
Query: 962 GQNCSKELDACQSQPCH-------------------------------NHGTCTPKP--- 987
C + + C+ +H P P
Sbjct: 904 QHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIYPCPVYS 963
Query: 988 -GGFHCACPPGF----------VGLRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLP 1036
FH CP G G+ D+DEC+ C + + C C
Sbjct: 964 SAEFHSLCPDGKGYTQDNNIVNYGIPAHRDIDECMLFGSEICKEGKCVNTQPGYECYCKQ 1023
Query: 1037 G--HTGQWCE-VEIDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFE---------GPTC 1084
G + G E V++D C + G CE T G G+ C C E P
Sbjct: 1024 GFYYDGNLLECVDVDECLDESNCRNGVCENTRG---GYRCACTPPAEYSPAQRQCLSPEE 1080
Query: 1085 SHRAPS----CGFHHCHHGGLCLPSPKPGFP-PRCACLSGYGGPDCLTPPAPKGCGPPSP 1139
RAP C G P P C C G G P P+G G P
Sbjct: 1081 MERAPERRDVCWSQRGEDGMCAGPLAGPALTFDDCCCRQGRGWGAQCRPCPPRGAGSHCP 1140
Query: 1140 CLYNGSCS--ETTGL---GGPGFRCSCPHSSPGPRCQKPGAKGCEGRSGDGACDAGCSGP 1194
+ S S +T+ L P S S RC + C R G C+ P
Sbjct: 1141 TSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCV---SGRCVPRPGGAVCEC----P 1193
Query: 1195 GG 1196
GG
Sbjct: 1194 GG 1195
Score = 138 bits (347), Expect = 6e-32
Identities = 165/627 (26%), Positives = 223/627 (35%), Gaps = 121/627 (19%)
Query: 32 PEPCANGGTCLSLSLGQGTCQCAPGFLGET-----CQFPDPCQNAQLC------------ 74
P C +GG C++ G C C PG+ + C+ D C++ C
Sbjct: 667 PHLCGDGGFCINFP-GHYKCNCYPGYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSF 725
Query: 75 -----------QNGGSCQALLPAPLGLPSSPS---PLTPSFLCTCLPGFT----GERC-- 114
Q GG+C+ + G P SP L SF CTC G+ G C
Sbjct: 726 KCIACQPGYRSQGGGACRDVNECAEGSPCSPGWCENLPGSFRCTCAQGYAPAPDGRSCLD 785
Query: 115 --QAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGW----TGEQCQLRDFCSANPCVNG 168
+ + D C CS G QC C+ G+ C+ D C G
Sbjct: 786 VDECEAGDVCDNGICSN-------TPGSFQCQCLSGYHLSRDRSHCEDIDECDFPAACIG 838
Query: 169 GVCLATYPQIQCHCPPGFE---GHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVG 225
G C+ T +C CP G G C+ D++EC QDP C +C N GS+ C+C G
Sbjct: 839 GDCINTNGSYRCLCPQGHRLVGGRKCQ-DIDECSQDPSLCLPHGACKNLQGSYVCVCDEG 897
Query: 226 ----QEGPRCELRAGPCPPRGC----SNGGTCQLMPEKDSTFHLCLCPPGF-IGPDCEVN 276
Q+ CE P + C + C + + T C C G G CE+
Sbjct: 898 FTPTQDQHGCEEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCEIY 957
Query: 277 PDNC-VSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNS 335
P C V + C DG YT G D+DEC G C+ G C N+
Sbjct: 958 P--CPVYSSAEFHSLCPDG-KGYTQDNNIVNYGIPAHRDIDECMLFGSEICKE-GKCVNT 1013
Query: 336 AGSFHCVCVSG--WGGTSCE-ENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHL 392
+ C C G + G E ++D+C+ + C + G + C C P
Sbjct: 1014 QPGYECYCKQGFYYDGNLLECVDVDECLDESNCRNGVCENTRGGYRCACTP--PAEYSPA 1071
Query: 393 EDMCLS------QPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPC 446
+ CLS P D S G +C +GP D D C +G
Sbjct: 1072 QRQCLSPEEMERAPERRDVCWSQRGEDG----MCAGPLAGPALTFD-DCCCRQGRG---- 1122
Query: 447 EHGGSCLNTPGSFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLLATFHCLCPPGLE 506
G C CPP GS C +E S S L L P +
Sbjct: 1123 -WGAQCRP--------CPPRGAGSHCPTSQSE--SNSFWDTSPLL--------LGKPPRD 1163
Query: 507 GQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGF----SGTRCEEDIDECRS----S 558
E +++EC C++ C G C C GF S RC DIDECR
Sbjct: 1164 EDSSEEDSDECR---CVS-GRCVPRPGGAVCECPGGFQLDASRARC-VDIDECRELNQRG 1218
Query: 559 PCANGGQCQDQPGAFHCKCLPGFEGPR 585
+C + G+F C C GF R
Sbjct: 1219 LLCKSERCVNTSGSFRCVCKAGFARSR 1245
Score = 107 bits (266), Expect = 2e-22
Identities = 115/394 (29%), Positives = 146/394 (37%), Gaps = 88/394 (22%)
Query: 905 GLCVDSGPSYFCHCPPGF----QGSLCQDHVNPCESRPCQNG-ATCMAQPSGYLCQCAPG 959
G CV P Y CHC PG+ Q C D VN CE+ PC G CM Y C C G
Sbjct: 588 GECVPGPPDYSCHCNPGYRSHPQHRYCVD-VNECEAEPCGPGRGICMNTGGSYNCHCNRG 646
Query: 960 Y------DGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPGFVGLR------CEGDV 1007
Y G++C + + C + G C PG + C C PG+ L+ CE D+
Sbjct: 647 YRLHVGAGGRSCVDLNECAKPHLCGDGGFCINFPGHYKCNCYPGY-RLKASRPPVCE-DI 704
Query: 1008 DECLDQPCHPTGTAACHSLANAFYC-QCLPGHTGQW---CEVEIDPCHSQPCFHGGTCEA 1063
DEC D P G C + +F C C PG+ Q C + PC G CE
Sbjct: 705 DECRDPSSCPDGK--CENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPC-SPGWCEN 761
Query: 1064 TAGSPLGFICHCPKGFEGPTCSHRAPSC-GFHHCHHGGLC---LPSPKPGFPPRCACLSG 1119
GS F C C +G+ P R SC C G +C + S PG +C CLSG
Sbjct: 762 LPGS---FRCTCAQGY-APAPDGR--SCLDVDECEAGDVCDNGICSNTPG-SFQCQCLSG 814
Query: 1120 YG-GPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKPGAKGC 1178
Y D C P+ C+ G C T G +RC CP + G + C
Sbjct: 815 YHLSRDRSHCEDIDECDFPAACI-GGDCINTNG----SYRCLCPQGH-----RLVGGRKC 864
Query: 1179 EGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDGQCHPQCDSEEC 1238
+ D +CS DP C H C +
Sbjct: 865 Q-------------------DIDECS---QDP-SLCLPHGAC----------------KN 885
Query: 1239 LFDGYDCETPPACTPAYDQYCHDHFHNGHCEKGC 1272
L Y C TP DQ+ + H +K C
Sbjct: 886 LQGSYVCVCDEGFTPTQDQHGCEEVEQPHHKKEC 919
Score = 82.0 bits (201), Expect = 5e-15
Identities = 149/586 (25%), Positives = 202/586 (34%), Gaps = 121/586 (20%)
Query: 686 PECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTCSEEMTA-----CHSGPCLN 740
P + LG C T QP G N C TA CH P L
Sbjct: 270 PPTQKPLGRCFQ------DTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQ 323
Query: 741 -GGSCNPSP--GGYYCTCPPSH---TGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCA 794
G P P G CP + CQ + + C +G C+N PG++ C+C
Sbjct: 324 YTGVQKPGPVRGEVGADCPQGYKRLNSTHCQDINECAMPGVCRHGD-CLNNPGSYRCVCP 382
Query: 795 MGFQGPRCEGKLRPSC-ADSP-----CRNRATCQDSPQGP--------RCLCPTGYTGGS 840
G G R C AD P C + + Q P C C G G+
Sbjct: 383 PG----HSLGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGA 438
Query: 841 ----CQTLMDLCAQKPCP--RNSHCLQTGPSFHCLCLQGWT---------GPLCNLPLSS 885
C T ++ CP + H L S L +QG + GP P
Sbjct: 439 RCQRCPTDGTAAFKEICPAGKGYHIL---TSHQTLTIQGESDFSLFLHPDGP----PKPQ 491
Query: 886 CQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATC 945
+ SQ G+ DS P + S+ Q H + P +
Sbjct: 492 QLPESPSQAPPPEDTEEERGVTTDS--------PVSEERSVQQSHPT-ATTTPARPYPEL 542
Query: 946 MAQPS-----GYLCQCAPGYDGQNCS----KELDACQ-SQPCHNHGTCTPKPGGFHCACP 995
+++PS +L P + E D C+ +Q HG C P P + C C
Sbjct: 543 ISRPSPPTMRWFLPDLPPSRSAVEIAPTQVTETDECRLNQNICGHGECVPGPPDYSCHCN 602
Query: 996 PGFVG---LRCEGDVDECLDQPCHPTGTAACHSLANAFYCQCLPGHT------GQWCEVE 1046
PG+ R DV+EC +PC P G C + ++ C C G+ G+ C V+
Sbjct: 603 PGYRSHPQHRYCVDVNECEAEPCGP-GRGICMNTGGSYNCHCNRGYRLHVGAGGRSC-VD 660
Query: 1047 IDPCHSQP--CFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSC-GFHHCHHGGLCL 1103
++ C ++P C GG C P + C+C G+ + R P C C C
Sbjct: 661 LNEC-AKPHLCGDGGFC---INFPGHYKCNCYPGYR--LKASRPPVCEDIDECRDPSSCP 714
Query: 1104 PSP---KPGFPPRCACLSGY---GGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGF 1157
KPG AC GY GG C C SPC G C G F
Sbjct: 715 DGKCENKPGSFKCIACQPGYRSQGGGACRD---VNECAEGSPC-SPGWCENLPG----SF 766
Query: 1158 RCSCPHSSPGPRCQKPGAKGC----EGRSGDGACDAG-CSGPGGNW 1198
RC+C P + C E +GD CD G CS G++
Sbjct: 767 RCTCAQG----YAPAPDGRSCLDVDECEAGD-VCDNGICSNTPGSF 807
Score = 58.2 bits (139), Expect = 8e-08
Identities = 39/117 (33%), Positives = 52/117 (44%), Gaps = 13/117 (11%)
Query: 411 PLTGSTLCLCQPGYS--GPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT 468
P+ G C GY T QD++EC M P C HG CLN PGS+ C+CPPG++
Sbjct: 332 PVRGEVGADCPQGYKRLNSTHCQDINECAM----PGVCRHG-DCLNNPGSYRCVCPPGHS 386
Query: 469 GSRCEADHNECLSQPCHPGSTCLDLLATFH-CLCP--PGLEGQLCEVETNECASAPC 522
+C++ S C L++ H C P L QLC + A C
Sbjct: 387 ---LGPSRTQCIADKPEEKSLCFRLVSPEHQCQHPLTTRLTRQLCCCSVGKAWGARC 440
Score = 42.7 bits (99), Expect = 0.004
Identities = 79/333 (23%), Positives = 109/333 (32%), Gaps = 56/333 (16%)
Query: 205 CPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGP------CPPRGCSNGGTCQLMPEKDST 258
C KG C ++ + +G+ G + G CP C NGG C S+
Sbjct: 75 CLKG-QCRDSCQQGSNMTLIGENGHSTDTLTGSGFRVVVCP-LPCMNGGQC-------SS 125
Query: 259 FHLCLCPPGFIGPDCEVNPDNCVSHQCQNG-GTCQDGLDTYTCLCPETWTGWDCSEDVDE 317
+ CLCPP F G C+V +G G + G + L P G +
Sbjct: 126 RNQCLCPPDFTGRFCQVPAGGAGGGTGGSGPGLSRTGALSTGALPPLAPEGDSVASKHAI 185
Query: 318 CETQ---GPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCA----PGSTC 370
Q PP G Q++A + G G S E + S
Sbjct: 186 YAVQVIADPPGPGEGPPAQHAA----FLVPLGPGQISAEVQAPPPVVNVRVHHPPEASVQ 241
Query: 371 IDRVGSFSCLCPPGRTGLLCHLEDMCLSQP-------CHGDA----QCSTNPLTGSTL-- 417
+ R+ S + LL H + P C D C +NPL G T
Sbjct: 242 VHRIESSNAESAAPSQHLLPHPKPSHPRPPTQKPLGRCFQDTLPKQPCGSNPLPGLTKQE 301
Query: 418 -CLCQPG--YSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGY---TGSR 471
C G + CH+ Q P P G CP GY +
Sbjct: 302 DCCGSIGTAWGQSKCHKCPQLQYTGVQKPGPVR---------GEVGADCPQGYKRLNSTH 352
Query: 472 CEADHNECLSQPCHPGSTCLDLLATFHCLCPPG 504
C+ D NEC CL+ ++ C+CPPG
Sbjct: 353 CQ-DINECAMPGVCRHGDCLNNPGSYRCVCPPG 384
Score = 42.7 bits (99), Expect = 0.004
Identities = 93/378 (24%), Positives = 119/378 (31%), Gaps = 72/378 (19%)
Query: 164 PCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCP 223
PC+NGG C + + QC CPP F G C+ G G S L S L P
Sbjct: 116 PCMNGGQCSS---RNQCLCPPDFTGRFCQVPAGGAGGGTGGSGPGLSRTGAL-STGALPP 171
Query: 224 VGQEGPRCELRAG----------PCPPRGCSNGGTCQLMPEKDSTFHL-CLCPPGFIG-- 270
+ EG + P P G L+P PP +
Sbjct: 172 LAPEGDSVASKHAIYAVQVIADPPGPGEGPPAQHAAFLVPLGPGQISAEVQAPPPVVNVR 231
Query: 271 ----PDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTG---WDCSEDV---DECET 320
P+ V S ++ Q L P T C +D C +
Sbjct: 232 VHHPPEASVQVHRIESSNAESAAPSQHLLPHPKPSHPRPPTQKPLGRCFQDTLPKQPCGS 291
Query: 321 QGPPHCRNGGTCQNSAGSFHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCL 380
P C S G + WG + C + PG G
Sbjct: 292 NPLPGLTKQEDCCGSIG-------TAWGQSKCHKCPQLQYTGVQKPGPV----RGEVGAD 340
Query: 381 CPPGRTGL-LCHLEDM---CLSQPC-HGDAQCSTNPLTGSTLCLCQPGYS-GPT---CHQ 431
CP G L H +D+ + C HGD C NP GS C+C PG+S GP+ C
Sbjct: 341 CPQGYKRLNSTHCQDINECAMPGVCRHGD--CLNNP--GSYRCVCPPGHSLGPSRTQCIA 396
Query: 432 DLDE----CLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYT-GSRCEADHNECLSQPCHP 486
D E C C+H + T C C G G+RC Q C
Sbjct: 397 DKPEEKSLCFRLVSPEHQCQHPLTTRLTRQL--CCCSVGKAWGARC---------QRCPT 445
Query: 487 GSTCLDLLATFHCLCPPG 504
T A F +CP G
Sbjct: 446 DGT-----AAFKEICPAG 458
Score = 42.7 bits (99), Expect = 0.004
Identities = 73/298 (24%), Positives = 96/298 (32%), Gaps = 66/298 (22%)
Query: 737 PCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMG 796
PC+NGG C+ C CPP TG CQ V A GGT + PG +
Sbjct: 116 PCMNGGQCSSRN---QCLCPPDFTGRFCQ------VPAGGAGGGTGGSGPG-------LS 159
Query: 797 FQGPRCEGKLRP------SCADSPCRNRATCQDSPQGPRCLCPTGYTG-----GSCQTLM 845
G G L P S A P GP P + G Q
Sbjct: 160 RTGALSTGALPPLAPEGDSVASKHAIYAVQVIADPPGPGEGPPAQHAAFLVPLGPGQISA 219
Query: 846 DLCAQKPCP-----------------RNSHCLQTGPSFHCL--CLQGWTGPLCNLPLSSC 886
++ A P +S+ PS H L P PL C
Sbjct: 220 EVQAPPPVVNVRVHHPPEASVQVHRIESSNAESAAPSQHLLPHPKPSHPRPPTQKPLGRC 279
Query: 887 QKAALSQ----GIDVSSLCHNGGLCVDSGPSY---FCHCPPGFQGSLCQDHVNPCESRPC 939
+ L + + L C G ++ CH P Q + Q P R
Sbjct: 280 FQDTLPKQPCGSNPLPGLTKQEDCCGSIGTAWGQSKCHKCPQLQYTGVQ---KPGPVRG- 335
Query: 940 QNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTCTPKPGGFHCACPPG 997
+ GA C P GY + +C ++++ C HG C PG + C CPPG
Sbjct: 336 EVGADC---PQGY-----KRLNSTHC-QDINECAMPGVCRHGDCLNNPGSYRCVCPPG 384
Score = 37.7 bits (86), Expect = 0.11
Identities = 92/407 (22%), Positives = 132/407 (32%), Gaps = 70/407 (17%)
Query: 6 LLLLLLLLLLLCVSVVRPRGLLCGSFPEPCANGGTCLSLSLGQGTCQCAPGFLGETC--- 62
L LLLLLLLLL R G G E A GG L+ + AP TC
Sbjct: 24 LALLLLLLLLLLGLGGRVEG---GPAGERGAGGGGALARE--RFKVVFAPVICKRTCLKG 78
Query: 63 QFPDPCQNAQ----LCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKL 118
Q D CQ + +NG S L + + P LP G +C ++
Sbjct: 79 QCRDSCQQGSNMTLIGENGHSTDTLTGSGFRVVVCP-----------LPCMNGGQCSSRN 127
Query: 119 EDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLRDFCSANPCVN--GGVCLATYP 176
+ CPP F + C + A G G TG + P ++ G + P
Sbjct: 128 QCLCPPDFTGR--FCQVPAGG------AGGGTG---------GSGPGLSRTGALSTGALP 170
Query: 177 QIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAG 236
+ HA V PGP + H L P+G E++A
Sbjct: 171 PLAPEGDSVASKHAIYA-VQVIADPPGPGEGPPAQHAAF-----LVPLGPGQISAEVQAP 224
Query: 237 P--------CPPRGCSNGGTCQLMPEKDSTFHLCLCP---PGFIGPDCEVNPDNCVSHQC 285
P PP + + + L P P P + C
Sbjct: 225 PPVVNVRVHHPPEASVQVHRIESSNAESAAPSQHLLPHPKPSHPRPPTQKPLGRCFQDTL 284
Query: 286 QN---GGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGSFHCV 342
G GL C T W S+ +C + G + G+
Sbjct: 285 PKQPCGSNPLPGLTKQEDCCGSIGTAWGQSK-CHKCPQLQYTGVQKPGPVRGEVGA---D 340
Query: 343 CVSGW---GGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRT 386
C G+ T C++ + + C G C++ GS+ C+CPPG +
Sbjct: 341 CPQGYKRLNSTHCQDINECAMPGVCRHGD-CLNNPGSYRCVCPPGHS 386
Score = 35.8 bits (81), Expect = 0.43
Identities = 22/61 (36%), Positives = 24/61 (39%), Gaps = 9/61 (14%)
Query: 1137 PSPCLYNGSCSETTGLGGPGFRCSCPHSSPGPRCQKP--GAKGCEGRSGDGACDAGCSGP 1194
P PC+ G CS +C CP G CQ P GA G G SG G G
Sbjct: 114 PLPCMNGGQCSSRN-------QCLCPPDFTGRFCQVPAGGAGGGTGGSGPGLSRTGALST 166
Query: 1195 G 1195
G
Sbjct: 167 G 167
Score = 32.0 bits (71), Expect = 6.2
Identities = 14/31 (45%), Positives = 16/31 (51%), Gaps = 3/31 (9%)
Query: 597 PCPVGASCLDLPGAFFCLCPSGFTGQLCEVP 627
PC G C CLCP FTG+ C+VP
Sbjct: 116 PCMNGGQCSSRNQ---CLCPPDFTGRFCQVP 143
Score = 32.0 bits (71), Expect = 6.2
Identities = 14/29 (48%), Positives = 15/29 (51%), Gaps = 3/29 (10%)
Query: 559 PCANGGQCQDQPGAFHCKCLPGFEGPRCQ 587
PC NGGQC + C C P F G CQ
Sbjct: 116 PCMNGGQCSSRN---QCLCPPDFTGRFCQ 141
Score = 31.6 bits (70), Expect = 8.2
Identities = 27/93 (29%), Positives = 37/93 (39%), Gaps = 18/93 (19%)
Query: 666 TCHHGHC----QRSSCVCDVGWTGPECEAELGGCISA-----PCAHGGTCYPQPSGYNCT 716
TC G C Q+ S + +G G + G PC +GG C S C
Sbjct: 74 TCLKGQCRDSCQQGSNMTLIGENGHSTDTLTGSGFRVVVCPLPCMNGGQC---SSRNQCL 130
Query: 717 CPTGYTGPTCSEEMTACHSGPCLNGGSCNPSPG 749
CP +TG C ++ A +G GG+ PG
Sbjct: 131 CPPDFTGRFC--QVPAGGAG----GGTGGSGPG 157
Score = 31.6 bits (70), Expect = 8.2
Identities = 18/71 (25%), Positives = 26/71 (36%), Gaps = 11/71 (15%)
Query: 656 PGCAPPEDNCTCHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNC 715
PG E C G+ + +S C ++ C G C P Y C
Sbjct: 330 PGPVRGEVGADCPQGYKRLNSTHCQ----------DINECAMPGVCRHGDCLNNPGSYRC 379
Query: 716 TCPTGYT-GPT 725
CP G++ GP+
Sbjct: 380 VCPPGHSLGPS 390
>gi|188528675 slit homolog 1 [Homo sapiens]
Length = 1534
Score = 201 bits (512), Expect = 5e-51
Identities = 92/245 (37%), Positives = 129/245 (52%), Gaps = 9/245 (3%)
Query: 689 EAELGGCISAPCAHGGTCYPQP-SGYNCTCPTGYTGPTCSEEMTACHSGPCLNGGSCNPS 747
+A+ C+S+PC + GTC+ P Y C CP+GY G C + +C SGPC NGG+C+
Sbjct: 923 QAKCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQ 982
Query: 748 PGG---YYCTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGPRCEG 804
G + C+CP GP C +TD CV C NGG CV+ G ++C C + ++G CE
Sbjct: 983 EGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQ 1042
Query: 805 KLRPSCAD-SPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHCLQTG 863
+ D +PC++ A C +P GPRC C GY G +C D C C + C+
Sbjct: 1043 LVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEV 1102
Query: 864 PSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQ 923
S+ CLC +G++G LC +P + +G + C NG CVD G C C PGF
Sbjct: 1103 NSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTE----CQNGANCVDQGNRPVCQCLPGFG 1158
Query: 924 GSLCQ 928
G C+
Sbjct: 1159 GPECE 1163
Score = 191 bits (486), Expect = 5e-48
Identities = 102/280 (36%), Positives = 132/280 (47%), Gaps = 19/280 (6%)
Query: 162 ANPCVNGGVCLATYP--QIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNT-LGSF 218
A P G L T P + +C PP A + + C P C +CHN L +
Sbjct: 894 AGPQDMEGKLLLTTPAKKFECQGPPTL---AVQAKCDLCLSSP--CQNQGTCHNDPLEVY 948
Query: 219 QCLCPVGQEGPRCELRAGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPD 278
+C CP G +G CE+ C C NGGTC +D+ F C CP GF GP C VN D
Sbjct: 949 RCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPF-TCSCPTGFEGPTCGVNTD 1007
Query: 279 NCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSAGS 338
+CV H C NGG C DG+ YTC CP + G C + VD C P C++ C +
Sbjct: 1008 DCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCSPDLNP-CQHEAQCVGTPDG 1066
Query: 339 FHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCHL------ 392
C C+ G+ G +C EN DDC C G+ C+D V S+SCLC G +G LC +
Sbjct: 1067 PRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPA 1126
Query: 393 -EDMCLSQPCHGDAQCSTNPLTGSTLCLCQPGYSGPTCHQ 431
+ C C A C +C C PG+ GP C +
Sbjct: 1127 PKSPCEGTECQNGANCVDQ--GNRPVCQCLPGFGGPECEK 1164
Score = 184 bits (466), Expect = 1e-45
Identities = 94/249 (37%), Positives = 120/249 (48%), Gaps = 23/249 (9%)
Query: 733 CHSGPCLNGGSCNPSPGGYY-CTCPPSHTGPQCQTSTDYCVSAPCFNGGTCVNRPGT--- 788
C S PC N G+C+ P Y C CP + G C+ S D C S PC NGGTC + G
Sbjct: 929 CLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAP 988
Query: 789 FSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMDLC 848
F+C C GF+GP C G C D C N C D C CP Y G +C+ L+DLC
Sbjct: 989 FTCSCPTGFEGPTC-GVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLC 1047
Query: 849 AQ--KPCPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGL 906
+ PC + C+ T C C+ G+ G C+ C+ C NG
Sbjct: 1048 SPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCR----------DHRCQNGAQ 1097
Query: 907 CVDSGPSYFCHCPPGFQGSLCQ--DHV----NPCESRPCQNGATCMAQPSGYLCQCAPGY 960
C+D SY C C G+ G LC+ H+ +PCE CQNGA C+ Q + +CQC PG+
Sbjct: 1098 CMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGF 1157
Query: 961 DGQNCSKEL 969
G C K L
Sbjct: 1158 GGPECEKLL 1166
Score = 174 bits (441), Expect = 8e-43
Identities = 89/247 (36%), Positives = 116/247 (46%), Gaps = 24/247 (9%)
Query: 810 CADSPCRNRATCQDSP-QGPRCLCPTGYTGGSCQTLMDLCAQKPCPRNSHC-LQTGPS-- 865
C SPC+N+ TC + P + RC CP+GY G C+ +D C+ PC C Q G
Sbjct: 929 CLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAP 988
Query: 866 FHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPSYFCHCPPGFQGS 925
F C C G+ GP C + C V C NGG+CVD +Y C CP ++G
Sbjct: 989 FTCSCPTGFEGPTCGVNTDDC----------VDHACANGGVCVDGVGNYTCQCPLQYEGK 1038
Query: 926 LCQDHVNPC--ESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHNHGTC 983
C+ V+ C + PCQ+ A C+ P G C+C PGY G NCS+ D C+ C N C
Sbjct: 1039 ACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQC 1098
Query: 984 TPKPGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAF------YCQCLPG 1037
+ + C C G+ G CE + L P P C + AN CQCLPG
Sbjct: 1099 MDEVNSYSCLCAEGYSGQLCE--IPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPG 1156
Query: 1038 HTGQWCE 1044
G CE
Sbjct: 1157 FGGPECE 1163
Score = 174 bits (440), Expect = 1e-42
Identities = 91/252 (36%), Positives = 121/252 (48%), Gaps = 26/252 (10%)
Query: 444 SPCEHGGSCLNTPGS-FNCLCPPGYTGSRCEADHNECLSQPCHPGSTCLDLL---ATFHC 499
SPC++ G+C N P + C CP GY G CE + C S PC G TC A F C
Sbjct: 932 SPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTC 991
Query: 500 LCPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRS-- 557
CP G EG C V T++C C N C D + + C C + G CE+ +D C
Sbjct: 992 SCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCSPDL 1051
Query: 558 SPCANGGQCQDQPGAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPGAFFCLCPS 617
+PC + QC P C+C+PG+ G C D+C C GA C+D ++ CLC
Sbjct: 1052 NPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVNSYSCLCAE 1111
Query: 618 GFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSC 677
G++GQLCE+P P+L PK C+ + C +G+ NC R C
Sbjct: 1112 GYSGQLCEIP---PHLPAPKSPCEGTE------CQNGA--------NCV---DQGNRPVC 1151
Query: 678 VCDVGWTGPECE 689
C G+ GPECE
Sbjct: 1152 QCLPGFGGPECE 1163
Score = 166 bits (419), Expect = 3e-40
Identities = 89/257 (34%), Positives = 115/257 (44%), Gaps = 30/257 (11%)
Query: 319 ETQGPPH--------------CRNGGTCQNSAGS-FHCVCVSGWGGTSCEENLDDCIAAT 363
E QGPP C+N GTC N + C C SG+ G CE +LD C +
Sbjct: 913 ECQGPPTLAVQAKCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGP 972
Query: 364 CAPGSTCIDRVGS---FSCLCPPGRTGLLCHLE-DMCLSQPCHGDAQCSTNPLTGSTLCL 419
C G TC + G F+C CP G G C + D C+ C C G+ C
Sbjct: 973 CENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDG--VGNYTCQ 1030
Query: 420 CQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEADHNEC 479
C Y G C Q +D C +PC+H C+ TP C C PGY G C + ++C
Sbjct: 1031 CPLQYEGKACEQLVDLC---SPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDC 1087
Query: 480 LSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEV------ETNECASAPCLNHADCHDLLN 533
C G+ C+D + ++ CLC G GQLCE+ + C C N A+C D N
Sbjct: 1088 RDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGN 1147
Query: 534 GFQCICLPGFSGTRCEE 550
C CLPGF G CE+
Sbjct: 1148 RPVCQCLPGFGGPECEK 1164
Score = 165 bits (418), Expect = 4e-40
Identities = 94/288 (32%), Positives = 120/288 (41%), Gaps = 19/288 (6%)
Query: 608 PGAFFCLCPSGFTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTC 667
PG C P G+L CQ Q CL +P ++ TC
Sbjct: 888 PGIARCAGPQDMEGKLLLTTPAKKFECQGPPTLAVQAKCDLCLS-------SPCQNQGTC 940
Query: 668 HHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQP---SGYNCTCPTGYTGP 724
H+ + C C G+ G +CE L C S PC +GGTC+ Q + + C+CPTG+ GP
Sbjct: 941 HNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGP 1000
Query: 725 TCSEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTDYCVSA--PCFNGGTC 782
TC C C NGG C G Y C CP + G C+ D C PC + C
Sbjct: 1001 TCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQC 1060
Query: 783 VNRPGTFSCLCAMGFQGPRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQ 842
V P C C G+ G C + C D C+N A C D CLC GY+G C+
Sbjct: 1061 VGTPDGPRCECMPGYAGDNCSEN-QDDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCE 1119
Query: 843 TLMDLCAQKP------CPRNSHCLQTGPSFHCLCLQGWTGPLCNLPLS 884
L A K C ++C+ G C CL G+ GP C LS
Sbjct: 1120 IPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGGPECEKLLS 1167
Score = 162 bits (411), Expect = 2e-39
Identities = 161/575 (28%), Positives = 210/575 (36%), Gaps = 126/575 (21%)
Query: 278 DNCVSHQCQNGGTCQ-DGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGTCQNSA 336
D C+S CQN GTC D L+ Y C CP + G DC +D C + GP C NGGTC
Sbjct: 927 DLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSS-GP--CENGGTCHAQE 983
Query: 337 GS---FHCVCVSGWGGTSCEENLDDCIAATCAPGSTCIDRVGSFSCLCPPGRTGLLCH-L 392
G F C C +G+ G +C N DDC+ CA G C+D VG+++C CP G C L
Sbjct: 984 GEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKACEQL 1043
Query: 393 EDMCLSQ--PCHGDAQCSTNP------------------------------------LTG 414
D+C PC +AQC P
Sbjct: 1044 VDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRCQNGAQCMDEVN 1103
Query: 415 STLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSCLNTPGSFNCLCPPGYTGSRCEA 474
S CLC GYSG C ++ L A + SPCE G C N G+ C
Sbjct: 1104 SYSCLCAEGYSGQLC--EIPPHLPAPK--SPCE-GTECQN--------------GANCVD 1144
Query: 475 DHNE--CLSQPCHPGSTCLDLLAT----------FHCLCPPGLEGQLCEVETNECASAPC 522
N C P G C LL+ F L +V T E
Sbjct: 1145 QGNRPVCQCLPGFGGPECEKLLSVNFVDRDTYLQFTDLQNWPRANITLQVSTAEDNGILL 1204
Query: 523 LNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPCANGGQCQDQPGAFHCKCLPGFE 582
N + H + +Q R D SS + D G FH L F+
Sbjct: 1205 YNGDNDHIAVELYQ-------GHVRVSYDPGSYPSSAIYSAETIND--GQFHTVELVAFD 1255
Query: 583 ----------GPRCQTEVDE--CLSDPCP--VGASCLDLPGAFFCLCP----SGFTGQLC 624
P + L+ P VG +D+ A F L +GF G
Sbjct: 1256 QMVNLSIDGGSPMTMDNFGKHYTLNSEAPLYVGGMPVDVNSAAFRLWQILNGTGFHG--- 1312
Query: 625 EVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSS-----CVC 679
C NL ++ K + P PGC P C HG CQ ++ C C
Sbjct: 1313 ----CIRNLYINNELQDFTKTQMK---PGVVPGCEPCR-KLYCLHGICQPNATPGPMCHC 1364
Query: 680 DVGWTGPECEAELGG-CISAPCAHGGTCYPQPS-GYNCTCPTGYTGPTCSEE---MTACH 734
+ GW G C+ G C C HG C P + Y+C C GY+G C++ C
Sbjct: 1365 EAGWVGLHCDQPADGPCHGHKCVHG-QCVPLDALSYSCQCQDGYSGALCNQAGALAEPCR 1423
Query: 735 SGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQTSTD 769
CL+G G +C C P +G C+ ++
Sbjct: 1424 GLQCLHGHCQASGTKGAHCVCDPGFSGELCEQESE 1458
Score = 160 bits (406), Expect = 9e-39
Identities = 86/251 (34%), Positives = 120/251 (47%), Gaps = 16/251 (6%)
Query: 115 QAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQLR-DFCSANPCVNGGVCLA 173
QAK D C S C +G CH +C+C G+ G C++ D CS+ PC NGG C A
Sbjct: 923 QAKC-DLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHA 981
Query: 174 TYPQ---IQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPR 230
+ C CP GFEG C + ++C C G C + +G++ C CP+ EG
Sbjct: 982 QEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHA--CANGGVCVDGVGNYTCQCPLQYEGKA 1039
Query: 231 CELRAGPCPP--RGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQCQNG 288
CE C P C + C P+ C C PG+ G +C N D+C H+CQNG
Sbjct: 1040 CEQLVDLCSPDLNPCQHEAQCVGTPDGPR----CECMPGYAGDNCSENQDDCRDHRCQNG 1095
Query: 289 GTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGP---PHCRNGGTCQNSAGSFHCVCVS 345
C D +++Y+CLC E ++G C + P C+NG C + C C+
Sbjct: 1096 AQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLP 1155
Query: 346 GWGGTSCEENL 356
G+GG CE+ L
Sbjct: 1156 GFGGPECEKLL 1166
Score = 150 bits (378), Expect = 2e-35
Identities = 91/266 (34%), Positives = 112/266 (42%), Gaps = 24/266 (9%)
Query: 916 CHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQP-SGYLCQCAPGYDGQNCSKELDACQS 974
C PP Q + C S PCQN TC P Y C C GY G++C LD+C S
Sbjct: 914 CQGPPTLA---VQAKCDLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSS 970
Query: 975 QPCHNHGTCTPKPGG---FHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFY 1031
PC N GTC + G F C+CP GF G C + D+C+D C G C +
Sbjct: 971 GPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGV--CVDGVGNYT 1028
Query: 1032 CQCLPGHTGQWCEVEIDPCHSQ--PCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAP 1089
CQC + G+ CE +D C PC H C G+P G C C G+ G CS
Sbjct: 1029 CQCPLQYEGKACEQLVDLCSPDLNPCQHEAQC---VGTPDGPRCECMPGYAGDNCSENQD 1085
Query: 1090 SCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTP---PAPKGCGPPSPCLYNGSC 1146
C H C +G C+ C C GY G C P PAPK + C +C
Sbjct: 1086 DCRDHRCQNGAQCMDEVN---SYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANC 1142
Query: 1147 SETTGLGGPGFRCSCPHSSPGPRCQK 1172
+ G C C GP C+K
Sbjct: 1143 VDQ----GNRPVCQCLPGFGGPECEK 1164
Score = 139 bits (351), Expect = 2e-32
Identities = 84/272 (30%), Positives = 105/272 (38%), Gaps = 38/272 (13%)
Query: 553 DECRSSPCANGGQCQDQP-GAFHCKCLPGFEGPRCQTEVDECLSDPCPVGASCLDLPG-- 609
D C SSPC N G C + P + C C G++G C+ +D C S PC G +C G
Sbjct: 927 DLCLSSPCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGPCENGGTCHAQEGED 986
Query: 610 -AFFCLCPSGFTGQLCEVPL--CAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCT 666
F C CP+GF G C V C + C +C D C CP G A
Sbjct: 987 APFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCPLQYEGKA------- 1039
Query: 667 CHHGHCQRSSCVCDVGWTGPECEAELGGCISAPCAHGGTCYPQPSGYNCTCPTGYTGPTC 726
C++ + D+ C +L C H C P G C C GY G C
Sbjct: 1040 -----CEQ---LVDL------CSPDLNPC-----QHEAQCVGTPDGPRCECMPGYAGDNC 1080
Query: 727 SEEMTACHSGPCLNGGSCNPSPGGYYCTCPPSHTGPQCQ------TSTDYCVSAPCFNGG 780
SE C C NG C Y C C ++G C+ C C NG
Sbjct: 1081 SENQDDCRDHRCQNGAQCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGA 1140
Query: 781 TCVNRPGTFSCLCAMGFQGPRCEGKLRPSCAD 812
CV++ C C GF GP CE L + D
Sbjct: 1141 NCVDQGNRPVCQCLPGFGGPECEKLLSVNFVD 1172
Score = 132 bits (332), Expect = 3e-30
Identities = 81/251 (32%), Positives = 108/251 (43%), Gaps = 30/251 (11%)
Query: 34 PCANGGTCLSLSLGQGTCQCAPGFLGETCQFP-DPCQNAQLCQNGGSCQALLPAPLGLPS 92
PC N GTC + L C C G+ G C+ D C + C+NGG+C A
Sbjct: 933 PCQNQGTCHNDPLEVYRCACPSGYKGRDCEVSLDSCSSGP-CENGGTCHA-------QEG 984
Query: 93 SPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGE 152
+P F C+C GF G C +D C C+ G C + G C C + G+
Sbjct: 985 EDAP----FTCSCPTGFEGPTCGVNTDD-CVDHACANGGVC-VDGVGNYTCQCPLQYEGK 1038
Query: 153 QC-QLRDFCS--ANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGT 209
C QL D CS NPC + C+ T +C C PG+ G C + ++C C G
Sbjct: 1039 ACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDH--RCQNGA 1096
Query: 210 SCHNTLGSFQCLCPVGQEGPRCEL------RAGPCPPRGCSNGGTCQLMPEKDSTFHLCL 263
C + + S+ CLC G G CE+ PC C NG C + +C
Sbjct: 1097 QCMDEVNSYSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNRP----VCQ 1152
Query: 264 CPPGFIGPDCE 274
C PGF GP+CE
Sbjct: 1153 CLPGFGGPECE 1163
Score = 131 bits (330), Expect = 6e-30
Identities = 82/256 (32%), Positives = 103/256 (40%), Gaps = 33/256 (12%)
Query: 67 PCQNAQLCQNGGSCQALLPAPLGLPSSPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSF 126
PCQN C N PL + + C C G+ G C+ L D C
Sbjct: 933 PCQNQGTCHND---------PLEV----------YRCACPSGYKGRDCEVSL-DSCSSGP 972
Query: 127 CSKRGRCHIQASGRPQ--CSCMPGWTGEQCQLR-DFCSANPCVNGGVCLATYPQIQCHCP 183
C G CH Q CSC G+ G C + D C + C NGGVC+ C CP
Sbjct: 973 CENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVGNYTCQCP 1032
Query: 184 PGFEGHACERDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCELRAGPCPPRGC 243
+EG ACE+ V+ C D PC C T +C C G G C C C
Sbjct: 1033 LQYEGKACEQLVDLCSPDLNPCQHEAQCVGTPDGPRCECMPGYAGDNCSENQDDCRDHRC 1092
Query: 244 SNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNP------DNCVSHQCQNGGTCQDGLDT 297
NG C M E +S + CLC G+ G CE+ P C +CQNG C D +
Sbjct: 1093 QNGAQC--MDEVNS--YSCLCAEGYSGQLCEIPPHLPAPKSPCEGTECQNGANCVDQGNR 1148
Query: 298 YTCLCPETWTGWDCSE 313
C C + G +C +
Sbjct: 1149 PVCQCLPGFGGPECEK 1164
Score = 115 bits (289), Expect = 3e-25
Identities = 98/310 (31%), Positives = 118/310 (38%), Gaps = 67/310 (21%)
Query: 990 FHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSLANAFY-CQCLPGHTGQWCEVEID 1048
F C PP L + D CL PC GT CH+ Y C C G+ G+ CEV +D
Sbjct: 912 FECQGPPT---LAVQAKCDLCLSSPCQNQGT--CHNDPLEVYRCACPSGYKGRDCEVSLD 966
Query: 1049 PCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKP 1108
C S PC +GGTC A G F C CP GFEGPTC C H C +GG+C+
Sbjct: 967 SCSSGPCENGGTCHAQEGEDAPFTCSCPTGFEGPTCGVNTDDCVDHACANGGVCVDGVG- 1025
Query: 1109 GFPPRCACLSGYGGPDCLTPPAPKGCGPP-SPCLYNGSCSETTGLGGPGFRCSCPHSSPG 1167
C C Y G C C P +PC + C +G P G
Sbjct: 1026 --NYTCQCPLQYEGKAC--EQLVDLCSPDLNPCQHEAQC-----VGTP----------DG 1066
Query: 1168 PRCQKPGAKGCEGRSGDGACDAGCSGPGGNWDGGDCSLGVPDPWKGCPSHSRCWLLFRDG 1227
PRC+ C G + G +CS D C H RC
Sbjct: 1067 PRCE---------------CMPG-------YAGDNCSENQDD----CRDH-RCQ---NGA 1096
Query: 1228 QCHPQCDSEECL----FDGYDCETPPACTPAYDQYCHDHFHNGHCEKGCNTAECG-WDGG 1282
QC + +S CL + G CE PP PA C C+ G N + G
Sbjct: 1097 QCMDEVNSYSCLCAEGYSGQLCEIPPH-LPAPKSPC----EGTECQNGANCVDQGNRPVC 1151
Query: 1283 DCRPEDGDPE 1292
C P G PE
Sbjct: 1152 QCLPGFGGPE 1161
Score = 85.9 bits (211), Expect = 4e-16
Identities = 52/176 (29%), Positives = 77/176 (43%), Gaps = 26/176 (14%)
Query: 35 CANGGTCLSLSLGQGTCQCAPGFLGETC-QFPDPCQ-NAQLCQNGGSCQALLPAPLGLPS 92
CANGG C+ +G TCQC + G+ C Q D C + CQ+ C +G P
Sbjct: 1014 CANGGVCVD-GVGNYTCQCPLQYEGKACEQLVDLCSPDLNPCQHEAQC-------VGTPD 1065
Query: 93 SPSPLTPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGE 152
P C C+PG+ G+ C +D C C +C + + C C G++G+
Sbjct: 1066 GPR-------CECMPGYAGDNCSEN-QDDCRDHRCQNGAQCMDEVNSY-SCLCAEGYSGQ 1116
Query: 153 QCQL-------RDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQD 201
C++ + C C NG C+ + C C PGF G CE+ ++ F D
Sbjct: 1117 LCEIPPHLPAPKSPCEGTECQNGANCVDQGNRPVCQCLPGFGGPECEKLLSVNFVD 1172
Score = 72.8 bits (177), Expect = 3e-12
Identities = 46/151 (30%), Positives = 59/151 (39%), Gaps = 15/151 (9%)
Query: 905 GLCVDSG-PSYFCHCPPGFQGSLCQDHVN-PCESRPCQNGATCMAQPSGYLCQCAPGYDG 962
G+C + P CHC G+ G C + PC C +G Y CQC GY G
Sbjct: 1350 GICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQCVPLDALSYSCQCQDGYSG 1409
Query: 963 QNCSKELDACQSQPCHN----HGTCTPK-PGGFHCACPPGFVGLRCEGDVDECLDQPCH- 1016
C++ ++PC HG C G HC C PGF G CE + EC P
Sbjct: 1410 ALCNQA--GALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQE-SECRGDPVRD 1466
Query: 1017 ----PTGTAACHSLANAFYCQCLPGHTGQWC 1043
G A C + + +C GQ C
Sbjct: 1467 FHQVQRGYAICQTTRPLSWVECRGSCPGQGC 1497
Score = 64.7 bits (156), Expect = 9e-10
Identities = 55/196 (28%), Positives = 77/196 (39%), Gaps = 42/196 (21%)
Query: 399 QPC------HGDAQCSTNPLTGSTLCLCQPGYSGPTCHQDLDECLMAQQGPSPCEHGGSC 452
+PC HG Q + P +C C+ G+ G C Q D PC HG C
Sbjct: 1340 EPCRKLYCLHGICQPNATP---GPMCHCEAGWVGLHCDQPAD---------GPC-HGHKC 1386
Query: 453 LNTPG------SFNCLCPPGYTGSRCEADHNECLSQPCHPGSTCL------DLLATFHCL 500
++ S++C C GY+G+ C + L++PC G CL HC+
Sbjct: 1387 VHGQCVPLDALSYSCQCQDGYSGALC--NQAGALAEPCR-GLQCLHGHCQASGTKGAHCV 1443
Query: 501 CPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQ-CICLPGFSGTRCEEDIDECRSSP 559
C PG G+LCE E +EC P D H + G+ C S C C
Sbjct: 1444 CDPGFSGELCEQE-SECRGDPV---RDFHQVQRGYAICQTTRPLSWVECR---GSCPGQG 1496
Query: 560 CANGGQCQDQPGAFHC 575
C G + + + F C
Sbjct: 1497 CCQGLRLKRRKFTFEC 1512
Score = 63.9 bits (154), Expect = 1e-09
Identities = 48/153 (31%), Positives = 61/153 (39%), Gaps = 29/153 (18%)
Query: 975 QPCHN----HGTCTPK--PGGFHCACPPGFVGLRCEGDVDECLDQPCHPTGTAACHSL-- 1026
+PC HG C P PG C C G+VGL C D+ D PCH G H
Sbjct: 1340 EPCRKLYCLHGICQPNATPGPM-CHCEAGWVGLHC----DQPADGPCH--GHKCVHGQCV 1392
Query: 1027 ---ANAFYCQCLPGHTGQWCEVE---IDPCHSQPCFHGGTCEATAGSPLGFICHCPKGFE 1080
A ++ CQC G++G C +PC C HG C+A+ G C C GF
Sbjct: 1393 PLDALSYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGH-CQASGTK--GAHCVCDPGFS 1449
Query: 1081 GPTCSHRA-----PSCGFHHCHHGGLCLPSPKP 1108
G C + P FH G + +P
Sbjct: 1450 GELCEQESECRGDPVRDFHQVQRGYAICQTTRP 1482
Score = 62.0 bits (149), Expect = 6e-09
Identities = 41/135 (30%), Positives = 53/135 (39%), Gaps = 25/135 (18%)
Query: 933 PCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDACQSQPCHN----HGTCTPKPG 988
PC C +G G +C C G+ G +C + D PCH HG C P
Sbjct: 1341 PCRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPADG----PCHGHKCVHGQCVPLDA 1396
Query: 989 -GFHCACPPGFVGLRCE--GDVDE------CLDQPCHPTGTAACHSLANAFYCQCLPGHT 1039
+ C C G+ G C G + E CL C +GT H C C PG +
Sbjct: 1397 LSYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAH-------CVCDPGFS 1449
Query: 1040 GQWCEVEIDPCHSQP 1054
G+ CE E + C P
Sbjct: 1450 GELCEQESE-CRGDP 1463
Score = 61.2 bits (147), Expect = 1e-08
Identities = 43/153 (28%), Positives = 61/153 (39%), Gaps = 13/153 (8%)
Query: 98 TPSFLCTCLPGFTGERCQAKLEDPCPPSFCSKRGRCHIQASGRPQCSCMPGWTGEQCQ-- 155
TP +C C G+ G C + PC C G+C + C C G++G C
Sbjct: 1357 TPGPMCHCEAGWVGLHCDQPADGPCHGHKCV-HGQCVPLDALSYSCQCQDGYSGALCNQA 1415
Query: 156 --LRDFCSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHN 213
L + C C++G + C C PGF G CE++ +EC DP H
Sbjct: 1416 GALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGELCEQE-SECRGDP-----VRDFHQ 1469
Query: 214 TLGSFQCLCPVGQEGPRCELRAGPCPPRGCSNG 246
+ +C + E R G CP +GC G
Sbjct: 1470 VQRGY-AICQTTRPLSWVECR-GSCPGQGCCQG 1500
Score = 58.2 bits (139), Expect = 8e-08
Identities = 52/179 (29%), Positives = 64/179 (35%), Gaps = 23/179 (12%)
Query: 800 PRCEGKLRPSCADSPCRNRATCQDSPQGPRCLCPTGYTGGSCQTLMD-LCAQKPCPRNSH 858
P CE + C C+ AT GP C C G+ G C D C C
Sbjct: 1337 PGCEPCRKLYCLHGICQPNAT-----PGPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQC 1391
Query: 859 CLQTGPSFHCLCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNGGLCVDSGPS-YFCH 917
S+ C C G++G LCN Q AL++ H G C SG C
Sbjct: 1392 VPLDALSYSCQCQDGYSGALCN------QAGALAEPCRGLQCLH--GHCQASGTKGAHCV 1443
Query: 918 CPPGFQGSLCQDHVNPCESRP------CQNG-ATCMAQPSGYLCQCAPGYDGQNCSKEL 969
C PGF G LC+ + C P Q G A C +C GQ C + L
Sbjct: 1444 CDPGFSGELCEQE-SECRGDPVRDFHQVQRGYAICQTTRPLSWVECRGSCPGQGCCQGL 1501
Score = 57.0 bits (136), Expect = 2e-07
Identities = 43/129 (33%), Positives = 54/129 (41%), Gaps = 22/129 (17%)
Query: 479 CLSQPCHPGSTCLDLLATFHCLCPPGLEGQLCEVETNECASAPCLNHADCH------DLL 532
CL C P +T + C C G G C+ + A PC H H D L
Sbjct: 1347 CLHGICQPNATPGPM-----CHCEAGWVGLHCD----QPADGPCHGHKCVHGQCVPLDAL 1397
Query: 533 NGFQCICLPGFSGTRCEED---IDECRSSPCANGG-QCQDQPGAFHCKCLPGFEGPRCQT 588
+ + C C G+SG C + + CR C +G Q GA HC C PGF G C+
Sbjct: 1398 S-YSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGA-HCVCDPGFSGELCEQ 1455
Query: 589 EVDECLSDP 597
E EC DP
Sbjct: 1456 E-SECRGDP 1463
Score = 55.8 bits (133), Expect = 4e-07
Identities = 50/182 (27%), Positives = 64/182 (35%), Gaps = 27/182 (14%)
Query: 266 PGFIGPDCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPH 325
PG + P CE C C +G + C C W G C + D GP H
Sbjct: 1333 PGVV-PGCEP----CRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPAD-----GPCH 1382
Query: 326 ---CRNGGTCQNSAGSFHCVCVSGWGGTSCEEN---LDDCIAATCAPGSTCIDRVGSFSC 379
C +G A S+ C C G+ G C + + C C G C
Sbjct: 1383 GHKCVHGQCVPLDALSYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHC 1442
Query: 380 LCPPGRTGLLCHLEDMCLSQPC-------HGDAQC-STNPLTGSTLCLCQPGYSGPTCHQ 431
+C PG +G LC E C P G A C +T PL+ C+ G C Q
Sbjct: 1443 VCDPGFSGELCEQESECRGDPVRDFHQVQRGYAICQTTRPLSWVE---CRGSCPGQGCCQ 1499
Query: 432 DL 433
L
Sbjct: 1500 GL 1501
Score = 53.9 bits (128), Expect = 2e-06
Identities = 37/137 (27%), Positives = 51/137 (37%), Gaps = 12/137 (8%)
Query: 686 PECEAELGGCISAPCAHGGTCYPQPS-GYNCTCPTGYTGPTCSEEMTA-CHSGPCLNGGS 743
P CE C C HG C P + G C C G+ G C + CH C++G
Sbjct: 1337 PGCEP----CRKLYCLHG-ICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVHGQC 1391
Query: 744 CNPSPGGYYCTCPPSHTGPQCQTS---TDYCVSAPCFNGGTCVNRPGTFSCLCAMGFQGP 800
Y C C ++G C + + C C +G + C+C GF G
Sbjct: 1392 VPLDALSYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGHCQASGTKGAHCVCDPGFSGE 1451
Query: 801 RCEGKLRPSCADSPCRN 817
CE + C P R+
Sbjct: 1452 LCEQE--SECRGDPVRD 1466
Score = 53.1 bits (126), Expect = 3e-06
Identities = 46/174 (26%), Positives = 60/174 (34%), Gaps = 31/174 (17%)
Query: 33 EPCAN----GGTCLSLSLGQGTCQCAPGFLGETCQFP--DPCQNAQLCQNGGSCQALLPA 86
EPC G C + C C G++G C P PC + G C
Sbjct: 1340 EPCRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPADGPCHGHKCVH--GQC-----V 1392
Query: 87 PLGLPSSPSPLTPSFLCTCLPGFTGERCQ--AKLEDPCPPSFCSKRGRCHIQASGRPQCS 144
PL S+ C C G++G C L +PC C G C + C
Sbjct: 1393 PLD--------ALSYSCQCQDGYSGALCNQAGALAEPCRGLQCL-HGHCQASGTKGAHCV 1443
Query: 145 CMPGWTGEQCQLRDFCSANPC-----VNGG--VCLATYPQIQCHCPPGFEGHAC 191
C PG++GE C+ C +P V G +C T P C G C
Sbjct: 1444 CDPGFSGELCEQESECRGDPVRDFHQVQRGYAICQTTRPLSWVECRGSCPGQGC 1497
Score = 50.4 bits (119), Expect = 2e-05
Identities = 39/126 (30%), Positives = 49/126 (38%), Gaps = 11/126 (8%)
Query: 1048 DPCHSQPCFHGGTCEATAGSPLGFICHCPKGFEGPTCSHRAPS-CGFHHCHHGGLCLPSP 1106
+PC C HG C+ A G +CHC G+ G C A C H C H G C+P
Sbjct: 1340 EPCRKLYCLHG-ICQPNATP--GPMCHCEAGWVGLHCDQPADGPCHGHKCVH-GQCVPLD 1395
Query: 1107 KPGFPPRCACLSGYGGPDCLTPPAPKGCGPPSPCLYNGSCSETTGLGGPGFRCSCPHSSP 1166
+ C C GY G C A CL+ G C + G G C C
Sbjct: 1396 ALSY--SCQCQDGYSGALCNQAGALAEPCRGLQCLH-GHCQAS---GTKGAHCVCDPGFS 1449
Query: 1167 GPRCQK 1172
G C++
Sbjct: 1450 GELCEQ 1455
Score = 48.9 bits (115), Expect = 5e-05
Identities = 57/217 (26%), Positives = 74/217 (34%), Gaps = 35/217 (16%)
Query: 160 CSANPCVNGGVCLATYPQIQCHCPPGFEGHACERDVNECFQDPGPCPKGTSCHNTLG--- 216
C C++G P CHC G+ G C++ + GPC H
Sbjct: 1342 CRKLYCLHGICQPNATPGPMCHCEAGWVGLHCDQPAD------GPCHGHKCVHGQCVPLD 1395
Query: 217 --SFQCLCPVGQEGPRCELR---AGPCPPRGCSNGGTCQLMPEKDSTFHLCLCPPGFIGP 271
S+ C C G G C A PC C +G CQ K + C+C PGF G
Sbjct: 1396 ALSYSCQCQDGYSGALCNQAGALAEPCRGLQCLHGH-CQASGTKGAH---CVCDPGFSGE 1451
Query: 272 DCEVNPDNCVSHQCQNGGTCQDGLDTYTCLCPETWTGWDCSEDVDECETQGPPHCRNGGT 331
CE C ++ Q G P +W E C QG C G
Sbjct: 1452 LCE-QESECRGDPVRDFHQVQRGYAICQTTRPLSWV-----ECRGSCPGQG---CCQGLR 1502
Query: 332 CQNSAGSFHCVCVSGWGGTSCEENLD---DCIAATCA 365
+ +F C GTS E ++ C A CA
Sbjct: 1503 LKRRKFTFECS-----DGTSFAEEVEKPTKCGCALCA 1534
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.140 0.493
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 116,331,637
Number of Sequences: 37866
Number of extensions: 7734183
Number of successful extensions: 61626
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 577
Number of HSP's successfully gapped in prelim test: 595
Number of HSP's that attempted gapping in prelim test: 21265
Number of HSP's gapped (non-prelim): 12935
length of query: 2003
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1886
effective length of database: 13,817,196
effective search space: 26059231656
effective search space used: 26059231656
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.