Search of human proteins with 52426774

Search of human proteins with 52426774

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|52426774 major histocompatibility complex, class II, DR
alpha precursor [Homo sapiens]
         (254 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|52426774 major histocompatibility complex, class II, DR alpha...   520   e-148
gi|24797074 major histocompatibility complex, class II, DP alpha...   304   6e-83
gi|4504401 major histocompatibility complex, class II, DO alpha ...   283   1e-76
gi|18426975 major histocompatibility complex, class II, DQ alpha...   278   3e-75
gi|239740916 PREDICTED: similar to MHC HLA-DQ alpha [Homo sapiens]    276   1e-74
gi|113430811 PREDICTED: similar to major histocompatibility comp...   276   2e-74
gi|239740798 PREDICTED: similar to MHC class II antigen [Homo sa...   276   2e-74
gi|169217612 PREDICTED: similar to major histocompatibility comp...   271   3e-73
gi|239740747 PREDICTED: similar to major histocompatibility comp...   271   3e-73
gi|239740697 PREDICTED: similar to major histocompatibility comp...   271   3e-73
gi|11095447 major histocompatibility complex, class II, DQ alpha...   271   5e-73
gi|239740861 PREDICTED: similar to major histocompatibility comp...   264   5e-71
gi|239513953 PREDICTED: similar to major histocompatibility comp...   264   5e-71
gi|169218140 PREDICTED: similar to major histocompatibility comp...   202   3e-52
gi|18765715 major histocompatibility complex, class II, DM alpha...    94   1e-19
gi|239752547 PREDICTED: similar to major histocompatibility comp...    93   3e-19
gi|4504399 major histocompatibility complex, class II, DM beta p...    75   6e-14
gi|239740920 PREDICTED: similar to major histocompatibility comp...    72   5e-13
gi|239740918 PREDICTED: similar to major histocompatibility comp...    72   5e-13
gi|239758095 PREDICTED: similar to major histocompatibility comp...    72   6e-13
gi|239740749 PREDICTED: similar to major histocompatibility comp...    72   6e-13
gi|239748820 PREDICTED: hypothetical protein XP_002346811 [Homo ...    71   8e-13
gi|239740859 PREDICTED: similar to major histocompatibility comp...    71   8e-13
gi|239740857 PREDICTED: similar to major histocompatibility comp...    71   8e-13
gi|24797076 major histocompatibility complex, class II, DP beta ...    71   1e-12
gi|52630344 major histocompatibility complex, class II, DR beta ...    70   1e-12
gi|239758090 PREDICTED: major histocompatibility complex, class ...    70   1e-12
gi|169168591 PREDICTED: similar to major histocompatibility comp...    69   3e-12
gi|239748785 PREDICTED: similar to HLA class II histocompatibili...    69   3e-12
gi|239740855 PREDICTED: similar to major histocompatibility comp...    69   3e-12

>gi|52426774 major histocompatibility complex, class II, DR alpha
           precursor [Homo sapiens]
          Length = 254

 Score =  520 bits (1338), Expect = e-148
 Identities = 254/254 (100%), Positives = 254/254 (100%)

Query: 1   MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVD 60
           MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVD
Sbjct: 1   MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVD 60

Query: 61  MAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNS 120
           MAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNS
Sbjct: 61  MAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNS 120

Query: 121 PVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLP 180
           PVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLP
Sbjct: 121 PVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLP 180

Query: 181 STEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFIIK 240
           STEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFIIK
Sbjct: 181 STEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFIIK 240

Query: 241 GLRKSNAAERRGPL 254
           GLRKSNAAERRGPL
Sbjct: 241 GLRKSNAAERRGPL 254


>gi|24797074 major histocompatibility complex, class II, DP alpha 1
           precursor [Homo sapiens]
          Length = 260

 Score =  304 bits (778), Expect = 6e-83
 Identities = 148/247 (59%), Positives = 180/247 (72%)

Query: 8   VLGFFIIAVLMSAQESWAIKEEHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDMAKKETV 67
           +L    +A L+S + + AIK +HV   A F      +GEFMF+FD DE+F+VD+ KKETV
Sbjct: 14  ILRALSLAFLLSLRGAGAIKADHVSTYAAFVQTHRPTGEFMFEFDEDEMFYVDLDKKETV 73

Query: 68  WRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTNSPVELREP 127
           W LEEFG+  SFEAQG LANIA+   NL  + +RSN+T  TN PPEVTV    PVEL +P
Sbjct: 74  WHLEEFGQAFSFEAQGGLANIAILNNNLNTLIQRSNHTQATNDPPEVTVFPKEPVELGQP 133

Query: 128 NVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYD 187
           N LIC IDKF PPV+NVTWL NG+ VT GV+E++FLPR D+ F KFHYL F+PS ED YD
Sbjct: 134 NTLICHIDKFFPPVLNVTWLCNGELVTEGVAESLFLPRTDYSFHKFHYLTFVPSAEDFYD 193

Query: 188 CRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFIIKGLRKSNA 247
           CRVEHWGLD+PLLKHWE   P  +PETTE V+CALGL +GLVGII+GT+ IIK LR  + 
Sbjct: 194 CRVEHWGLDQPLLKHWEAQEPIQMPETTETVLCALGLVLGLVGIIVGTVLIIKSLRSGHD 253

Query: 248 AERRGPL 254
              +G L
Sbjct: 254 PRAQGTL 260


>gi|4504401 major histocompatibility complex, class II, DO alpha
           precursor [Homo sapiens]
          Length = 250

 Score =  283 bits (723), Expect = 1e-76
 Identities = 134/242 (55%), Positives = 171/242 (70%), Gaps = 1/242 (0%)

Query: 1   MAISGVPVLGFFIIAVLMSAQESWAIKEEHV-IIQAEFYLNPDQSGEFMFDFDGDEIFHV 59
           MA+    VLGF  +  L+S QE+ A K +H+      FY +   SG+F  +FD +++F V
Sbjct: 1   MALRAGLVLGFHTLMTLLSPQEAGATKADHMGSYGPAFYQSYGASGQFTHEFDEEQLFSV 60

Query: 60  DMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTN 119
           D+ K E VWRL EFG FA F+ QG LA IA  KA+L+I+ +RSN +   NVPP VTVL  
Sbjct: 61  DLKKSEAVWRLPEFGDFARFDPQGGLAGIAAIKAHLDILVERSNRSRAINVPPRVTVLPK 120

Query: 120 SPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFL 179
           S VEL +PN+LIC +D   PPV+N+TWLRNG+ VT GV++T F  + DHLFRKFHYLPF+
Sbjct: 121 SRVELGQPNILICIVDNIFPPVINITWLRNGQTVTEGVAQTSFYSQPDHLFRKFHYLPFV 180

Query: 180 PSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFII 239
           PS EDVYDC+VEHWGLD PLL+HWE   P P P+  E +VCALGL +GLVG ++GT+ II
Sbjct: 181 PSAEDVYDCQVEHWGLDAPLLRHWELQVPIPPPDAMETLVCALGLAIGLVGFLVGTVLII 240

Query: 240 KG 241
            G
Sbjct: 241 MG 242


>gi|18426975 major histocompatibility complex, class II, DQ alpha 1
           precursor [Homo sapiens]
          Length = 255

 Score =  278 bits (711), Expect = 3e-75
 Identities = 136/255 (53%), Positives = 173/255 (67%), Gaps = 1/255 (0%)

Query: 1   MAISGVPVLGFFIIAVLMSAQESWAIKEEHVI-IQAEFYLNPDQSGEFMFDFDGDEIFHV 59
           M ++   +LG   +  +MS      I  +HV       Y     SG++  +FDGDE F+V
Sbjct: 1   MILNKALLLGALALTTVMSPCGGEDIVADHVASCGVNLYQFYGPSGQYTHEFDGDEQFYV 60

Query: 60  DMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTN 119
           D+ +KET WR  EF +F  F+ QGAL N+AV K NL IM KR N T  TN  PEVTV + 
Sbjct: 61  DLERKETAWRWPEFSKFGGFDPQGALRNMAVAKHNLNIMIKRYNSTAATNEVPEVTVFSK 120

Query: 120 SPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFL 179
           SPV L +PN LIC +D   PPVVN+TWL NG+ VT GVSET FL + DH F K  YL FL
Sbjct: 121 SPVTLGQPNTLICLVDNIFPPVVNITWLSNGQSVTEGVSETSFLSKSDHSFFKISYLTFL 180

Query: 180 PSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFII 239
           PS +++YDC+VEHWGLD+PLLKHWE + P+P+ E TE VVCALGL+VGL+GI++GT+FII
Sbjct: 181 PSADEIYDCKVEHWGLDQPLLKHWEPEIPAPMSELTETVVCALGLSVGLMGIVVGTVFII 240

Query: 240 KGLRKSNAAERRGPL 254
           +GLR   A+  +GPL
Sbjct: 241 QGLRSVGASRHQGPL 255


>gi|239740916 PREDICTED: similar to MHC HLA-DQ alpha [Homo sapiens]
          Length = 255

 Score =  276 bits (706), Expect = 1e-74
 Identities = 138/255 (54%), Positives = 173/255 (67%), Gaps = 1/255 (0%)

Query: 1   MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQA-EFYLNPDQSGEFMFDFDGDEIFHV 59
           M ++   +LG   +  +MS      I  +HV       Y +   SG++  +FDGDE F+V
Sbjct: 1   MILNKALMLGALALTTVMSPCGGEDIVADHVASYGVNLYQSYGPSGQYSHEFDGDEEFYV 60

Query: 60  DMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTN 119
           D+ +KETVW+L  F RF  F+ Q AL NIAV K NL I+ KRSN T  TN  PEVTV + 
Sbjct: 61  DLERKETVWQLPLFRRFRRFDPQFALTNIAVLKHNLNIVIKRSNSTAATNEVPEVTVFSK 120

Query: 120 SPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFL 179
           SPV L +PN LIC +D   PPVVN+TWL NG  VT GVSET FL + DH F K  YL FL
Sbjct: 121 SPVTLGQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTFL 180

Query: 180 PSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFII 239
           PS +++YDC+VEHWGLDEPLLKHWE + P+P+ E TE VVCALGL+VGLVGI++GT+ II
Sbjct: 181 PSADEIYDCKVEHWGLDEPLLKHWEPEIPTPMSELTETVVCALGLSVGLVGIVVGTVLII 240

Query: 240 KGLRKSNAAERRGPL 254
           +GLR   A+  +GPL
Sbjct: 241 RGLRSVGASRHQGPL 255


>gi|113430811 PREDICTED: similar to major histocompatibility
           complex, class II, DQ alpha 1 [Homo sapiens]
          Length = 255

 Score =  276 bits (705), Expect = 2e-74
 Identities = 138/255 (54%), Positives = 173/255 (67%), Gaps = 1/255 (0%)

Query: 1   MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQA-EFYLNPDQSGEFMFDFDGDEIFHV 59
           M ++   +LG   +  +MS      I  +HV       Y +   SG++  +FDGDE F+V
Sbjct: 1   MILNKALMLGALALTTVMSPCGGEDIVADHVASYGVNLYQSYGPSGQYSHEFDGDEEFYV 60

Query: 60  DMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTN 119
           D+ +KETVW+L  F RF  F+ Q AL NIAV K NL I+ KRSN T  TN  PEVTV + 
Sbjct: 61  DLERKETVWQLPLFRRFRRFDPQFALTNIAVLKHNLNIVIKRSNSTAATNEVPEVTVFSK 120

Query: 120 SPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFL 179
           SPV L +PN LIC +D   PPVVN+TWL NG  VT GVSET FL + DH F K  YL FL
Sbjct: 121 SPVTLGQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTFL 180

Query: 180 PSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFII 239
           PS +++YDC+VEHWGLDEPLLKHWE + P+P+ E TE VVCALGL+VGLVGI++GT+ II
Sbjct: 181 PSDDEIYDCKVEHWGLDEPLLKHWEPEIPAPMSELTETVVCALGLSVGLVGIVVGTVLII 240

Query: 240 KGLRKSNAAERRGPL 254
           +GLR   A+  +GPL
Sbjct: 241 RGLRSVGASRHQGPL 255


>gi|239740798 PREDICTED: similar to MHC class II antigen [Homo
           sapiens]
          Length = 255

 Score =  276 bits (705), Expect = 2e-74
 Identities = 138/255 (54%), Positives = 173/255 (67%), Gaps = 1/255 (0%)

Query: 1   MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQA-EFYLNPDQSGEFMFDFDGDEIFHV 59
           M ++   +LG   +  +MS      I  +HV       Y +   SG++  +FDGDE F+V
Sbjct: 1   MILNKALMLGALALTTVMSPCGGEDIVADHVASYGVNLYQSYGPSGQYSHEFDGDEEFYV 60

Query: 60  DMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTN 119
           D+ +KETVW+L  F RF  F+ Q AL NIAV K NL I+ KRSN T  TN  PEVTV + 
Sbjct: 61  DLERKETVWQLPLFRRFRRFDPQFALTNIAVLKHNLNIVIKRSNSTAATNEVPEVTVFSK 120

Query: 120 SPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFL 179
           SPV L +PN LIC +D   PPVVN+TWL NG  VT GVSET FL + DH F K  YL FL
Sbjct: 121 SPVTLGQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTFL 180

Query: 180 PSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFII 239
           PS +++YDC+VEHWGLDEPLLKHWE + P+P+ E TE VVCALGL+VGLVGI++GT+ II
Sbjct: 181 PSDDEIYDCKVEHWGLDEPLLKHWEPEIPTPMSELTETVVCALGLSVGLVGIVVGTVLII 240

Query: 240 KGLRKSNAAERRGPL 254
           +GLR   A+  +GPL
Sbjct: 241 RGLRSVGASRHQGPL 255


>gi|169217612 PREDICTED: similar to major histocompatibility
           complex, class II, DQ alpha 1 isoform 1 [Homo sapiens]
          Length = 254

 Score =  271 bits (694), Expect = 3e-73
 Identities = 138/255 (54%), Positives = 172/255 (67%), Gaps = 2/255 (0%)

Query: 1   MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQA-EFYLNPDQSGEFMFDFDGDEIFHV 59
           M ++   +LG   +  +MS      I  +HV       Y +   SG+F  +FDGDE F+V
Sbjct: 1   MILNKALMLGALALTTVMSPCGGEDIVADHVASYGVNLYQSYGPSGQFTHEFDGDEEFYV 60

Query: 60  DMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTN 119
           D+ +KETVW+L  F R   F+ Q AL NIAV K NL I+ KRSN T  TN  PEVTV + 
Sbjct: 61  DLERKETVWKLPLFHRLR-FDPQFALTNIAVLKHNLNILIKRSNSTAATNEVPEVTVFSK 119

Query: 120 SPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFL 179
           SPV L +PN LIC +D   PPVVN+TWL NG  VT GVSET FL + DH F K  YL FL
Sbjct: 120 SPVTLGQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTFL 179

Query: 180 PSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFII 239
           PS +++YDC+VEHWGLDEPLLKHWE + P+P+ E TE VVCALGL+VGLVGI++GT+ II
Sbjct: 180 PSADEIYDCKVEHWGLDEPLLKHWEPEIPAPMSELTETVVCALGLSVGLVGIVVGTVLII 239

Query: 240 KGLRKSNAAERRGPL 254
           +GLR   A+  +GPL
Sbjct: 240 RGLRSVGASRHQGPL 254


>gi|239740747 PREDICTED: similar to major histocompatibility
           complex, class II, DQ alpha 1 [Homo sapiens]
          Length = 254

 Score =  271 bits (694), Expect = 3e-73
 Identities = 138/255 (54%), Positives = 172/255 (67%), Gaps = 2/255 (0%)

Query: 1   MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQA-EFYLNPDQSGEFMFDFDGDEIFHV 59
           M ++   +LG   +  +MS      I  +HV       Y +   SG+F  +FDGDE F+V
Sbjct: 1   MILNKALMLGALALTTVMSPCGGEDIVADHVASYGVNLYQSYGPSGQFTHEFDGDEEFYV 60

Query: 60  DMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTN 119
           D+ +KETVW+L  F R   F+ Q AL NIAV K NL I+ KRSN T  TN  PEVTV + 
Sbjct: 61  DLERKETVWKLPLFHRLR-FDPQFALTNIAVLKHNLNILIKRSNSTAATNEVPEVTVFSK 119

Query: 120 SPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFL 179
           SPV L +PN LIC +D   PPVVN+TWL NG  VT GVSET FL + DH F K  YL FL
Sbjct: 120 SPVTLGQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTFL 179

Query: 180 PSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFII 239
           PS +++YDC+VEHWGLDEPLLKHWE + P+P+ E TE VVCALGL+VGLVGI++GT+ II
Sbjct: 180 PSADEIYDCKVEHWGLDEPLLKHWEPEIPAPMSELTETVVCALGLSVGLVGIVVGTVLII 239

Query: 240 KGLRKSNAAERRGPL 254
           +GLR   A+  +GPL
Sbjct: 240 RGLRSVGASRHQGPL 254


>gi|239740697 PREDICTED: similar to major histocompatibility
           complex, class II, DQ alpha 1 [Homo sapiens]
          Length = 254

 Score =  271 bits (694), Expect = 3e-73
 Identities = 138/255 (54%), Positives = 172/255 (67%), Gaps = 2/255 (0%)

Query: 1   MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQA-EFYLNPDQSGEFMFDFDGDEIFHV 59
           M ++   +LG   +  +MS      I  +HV       Y +   SG+F  +FDGDE F+V
Sbjct: 1   MILNKALMLGALALTTVMSPCGGEDIVADHVASYGVNLYQSYGPSGQFTHEFDGDEEFYV 60

Query: 60  DMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTN 119
           D+ +KETVW+L  F R   F+ Q AL NIAV K NL I+ KRSN T  TN  PEVTV + 
Sbjct: 61  DLERKETVWKLPLFHRLR-FDPQFALTNIAVLKHNLNILIKRSNSTAATNEVPEVTVFSK 119

Query: 120 SPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFL 179
           SPV L +PN LIC +D   PPVVN+TWL NG  VT GVSET FL + DH F K  YL FL
Sbjct: 120 SPVTLGQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTFL 179

Query: 180 PSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFII 239
           PS +++YDC+VEHWGLDEPLLKHWE + P+P+ E TE VVCALGL+VGLVGI++GT+ II
Sbjct: 180 PSADEIYDCKVEHWGLDEPLLKHWEPEIPAPMSELTETVVCALGLSVGLVGIVVGTVLII 239

Query: 240 KGLRKSNAAERRGPL 254
           +GLR   A+  +GPL
Sbjct: 240 RGLRSVGASRHQGPL 254


>gi|11095447 major histocompatibility complex, class II, DQ alpha 2
           [Homo sapiens]
          Length = 255

 Score =  271 bits (692), Expect = 5e-73
 Identities = 133/255 (52%), Positives = 172/255 (67%), Gaps = 1/255 (0%)

Query: 1   MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQA-EFYLNPDQSGEFMFDFDGDEIFHV 59
           M ++   +LG   +  +MS      I  +HV      FY +   SG++  +FDGDE F+V
Sbjct: 1   MILNKALLLGALALTAVMSPCGGEDIVADHVASYGVNFYQSHGPSGQYTHEFDGDEEFYV 60

Query: 60  DMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTN 119
           D+  KETVW+L  F +F SF+ Q AL N+AV K  LE M ++SN T  TN  PEVTV + 
Sbjct: 61  DLETKETVWQLPMFSKFISFDPQSALRNMAVGKHTLEFMMRQSNSTAATNEVPEVTVFSK 120

Query: 120 SPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFL 179
            PV L +PN LIC +D   PPVVN+TWL NG  VT GVSET FL + DH F K  YL FL
Sbjct: 121 FPVTLGQPNTLICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTFL 180

Query: 180 PSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFII 239
           PS +++YDC+VEHWGLDEPLLKHWE + P+P+ E TE +VCALGL+VGL+GI++GT+FII
Sbjct: 181 PSADEIYDCKVEHWGLDEPLLKHWEPEIPAPMSELTETLVCALGLSVGLMGIVVGTVFII 240

Query: 240 KGLRKSNAAERRGPL 254
           +GLR   A+  +G L
Sbjct: 241 QGLRSVGASRHQGLL 255


>gi|239740861 PREDICTED: similar to major histocompatibility
           complex, class II, DQ alpha 1 [Homo sapiens]
          Length = 254

 Score =  264 bits (675), Expect = 5e-71
 Identities = 135/255 (52%), Positives = 170/255 (66%), Gaps = 2/255 (0%)

Query: 1   MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQA-EFYLNPDQSGEFMFDFDGDEIFHV 59
           M ++   +LG   +  +MS      I  +HV       Y +   SG++  +FDGDE F+V
Sbjct: 1   MILNKALMLGALALTTVMSPCGGEDIVADHVASYGVNLYQSYGPSGQYTHEFDGDEQFYV 60

Query: 60  DMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTN 119
           D+ +KETVW L    +F  F+ Q AL NIAV K NL  + KRSN T  TN  PEVTV + 
Sbjct: 61  DLGRKETVWCLPVLRQFR-FDPQFALTNIAVLKHNLNSLIKRSNSTAATNEVPEVTVFSK 119

Query: 120 SPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFL 179
           SPV L +PN+LIC +D   PPVVN+TWL NG  VT GVSET FL + DH F K  YL  L
Sbjct: 120 SPVTLGQPNILICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTLL 179

Query: 180 PSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFII 239
           PS E+ YDC+VEHWGLD+PLLKHWE + P+P+ E TE VVCALGL+VGLVGI++GT+FII
Sbjct: 180 PSAEESYDCKVEHWGLDKPLLKHWEPEIPAPMSELTETVVCALGLSVGLVGIVVGTVFII 239

Query: 240 KGLRKSNAAERRGPL 254
           +GLR   A+  +GPL
Sbjct: 240 RGLRSVGASRHQGPL 254


>gi|239513953 PREDICTED: similar to major histocompatibility
           complex, class II, DQ alpha 1 [Homo sapiens]
          Length = 254

 Score =  264 bits (675), Expect = 5e-71
 Identities = 135/255 (52%), Positives = 170/255 (66%), Gaps = 2/255 (0%)

Query: 1   MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQA-EFYLNPDQSGEFMFDFDGDEIFHV 59
           M ++   +LG   +  +MS      I  +HV       Y +   SG++  +FDGDE F+V
Sbjct: 1   MILNKALMLGALALTTVMSPCGGEDIVADHVASYGVNLYQSYGPSGQYTHEFDGDEQFYV 60

Query: 60  DMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTN 119
           D+ +KETVW L    +F  F+ Q AL NIAV K NL  + KRSN T  TN  PEVTV + 
Sbjct: 61  DLGRKETVWCLPVLRQFR-FDPQFALTNIAVLKHNLNSLIKRSNSTAATNEVPEVTVFSK 119

Query: 120 SPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFL 179
           SPV L +PN+LIC +D   PPVVN+TWL NG  VT GVSET FL + DH F K  YL  L
Sbjct: 120 SPVTLGQPNILICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKSDHSFFKISYLTLL 179

Query: 180 PSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFII 239
           PS E+ YDC+VEHWGLD+PLLKHWE + P+P+ E TE VVCALGL+VGLVGI++GT+FII
Sbjct: 180 PSAEESYDCKVEHWGLDKPLLKHWEPEIPAPMSELTETVVCALGLSVGLVGIVVGTVFII 239

Query: 240 KGLRKSNAAERRGPL 254
           +GLR   A+  +GPL
Sbjct: 240 RGLRSVGASRHQGPL 254


>gi|169218140 PREDICTED: similar to major histocompatibility
           complex, class II, DQ alpha 1, partial [Homo sapiens]
          Length = 153

 Score =  202 bits (513), Expect = 3e-52
 Identities = 92/148 (62%), Positives = 112/148 (75%)

Query: 107 ITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPRE 166
           +T   PEVTV + SPV L +PN+LIC +D   PPVVN+TWL NG  VT GVSET FL + 
Sbjct: 6   LTTEVPEVTVFSKSPVTLGQPNILICLVDNIFPPVVNITWLSNGHSVTEGVSETSFLSKS 65

Query: 167 DHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTV 226
           DH F K  YL  LPS E+ YDC+VEHWGLD+PLLKHWE + P+P+ E TE VVCALGL+V
Sbjct: 66  DHSFFKISYLTLLPSAEESYDCKVEHWGLDKPLLKHWEPEIPAPMSELTETVVCALGLSV 125

Query: 227 GLVGIIIGTIFIIKGLRKSNAAERRGPL 254
           GLVGI++GT+FII+GLR   A+  +GPL
Sbjct: 126 GLVGIVVGTVFIIRGLRSVGASRHQGPL 153


>gi|18765715 major histocompatibility complex, class II, DM alpha
           precursor [Homo sapiens]
          Length = 261

 Score = 94.0 bits (232), Expect = 1e-19
 Identities = 67/243 (27%), Positives = 104/243 (42%), Gaps = 20/243 (8%)

Query: 13  IIAVLMSAQESWAIKE-----------EHVIIQAEFYLNPDQSGEFMFDFDGDEIFHVDM 61
           ++ +L     SWA+ E            H  +   +  +   S      +D D++F  D 
Sbjct: 14  MLPLLWLLPHSWAVPEAPTPMWPDDLQNHTFLHTVYCQDGSPSVGLSEAYDEDQLFFFDF 73

Query: 62  AKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMT-----KRSNYTPITNVPPEVTV 116
           ++   V RL EF  +A  + QG    I  DK   E M      K     P++   P   V
Sbjct: 74  SQNTRVPRLPEFADWA--QEQGDAPAILFDKEFCEWMIQQIGPKLDGKIPVSRGFPIAEV 131

Query: 117 LTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYL 176
            T  P+E  +PN L+CF+    PP++ V W  +  PV  G   T     +   F+ F YL
Sbjct: 132 FTLKPLEFGKPNTLVCFVSNLFPPMLTVNWQHHSVPV-EGFGPTFVSAVDGLSFQAFSYL 190

Query: 177 PFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTI 236
            F P   D++ C V H       + +W      P  +  ENV+C +   +G++GII+G +
Sbjct: 191 NFTPEPSDIFSCIVTHEIDRYTAIAYWVPRNALP-SDLLENVLCGVAFGLGVLGIIVGIV 249

Query: 237 FII 239
            II
Sbjct: 250 LII 252


>gi|239752547 PREDICTED: similar to major histocompatibility
           complex, class II, DQ alpha 1, partial [Homo sapiens]
          Length = 130

 Score = 92.8 bits (229), Expect = 3e-19
 Identities = 56/131 (42%), Positives = 75/131 (57%), Gaps = 2/131 (1%)

Query: 1   MAISGVPVLGFFIIAVLMSAQESWAIKEEHVIIQA-EFYLNPDQSGEFMFDFDGDEIFHV 59
           M ++   +LG   +  +MS      I  +HV       Y +   SG++  +FDGDE F+V
Sbjct: 1   MILNKALMLGALALTTVMSPCGGEDIVADHVASYGVNLYQSYGPSGQYTHEFDGDEQFYV 60

Query: 60  DMAKKETVWRLEEFGRFASFEAQGALANIAVDKANLEIMTKRSNYTPITNVPPEVTVLTN 119
           D+ +KETVW L    +F  F+ Q AL NIAV K NL  + KRSN T  TN  PEVTV + 
Sbjct: 61  DLGRKETVWCLPVLRQFR-FDPQFALTNIAVLKHNLNSLIKRSNSTAATNEVPEVTVFSK 119

Query: 120 SPVELREPNVL 130
           SPV L +PN+L
Sbjct: 120 SPVTLGQPNIL 130


>gi|4504399 major histocompatibility complex, class II, DM beta
           precursor [Homo sapiens]
          Length = 263

 Score = 75.1 bits (183), Expect = 6e-14
 Identities = 46/127 (36%), Positives = 64/127 (50%), Gaps = 3/127 (2%)

Query: 111 PPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVS-ETVFLPREDHL 169
           PP V V   +P   REP +L C++  F P  V +TW +NGK V    S      P  D  
Sbjct: 114 PPSVQVAKTTPFNTREPVMLACYVWGFYPAEVTITWRKNGKLVMPHSSAHKTAQPNGDWT 173

Query: 170 FRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLV 229
           ++   +L   PS  D Y C VEH G  EP+L+ W     SP+ +T +  V A+ L +GL+
Sbjct: 174 YQTLSHLALTPSYGDTYTCVVEHIGAPEPILRDWT-PGLSPM-QTLKVSVSAVTLGLGLI 231

Query: 230 GIIIGTI 236
              +G I
Sbjct: 232 IFSLGVI 238


>gi|239740920 PREDICTED: similar to major histocompatibility
           complex, class II, DQ beta 1 isoform 2 [Homo sapiens]
          Length = 261

 Score = 72.0 bits (175), Expect = 5e-13
 Identities = 41/133 (30%), Positives = 59/133 (44%), Gaps = 10/133 (7%)

Query: 110 VPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHL 169
           V P VT+  +    L   N+L+C +  F P  + V W RN +  TTGV  T  +   D  
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIRNGDWT 186

Query: 170 FRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLV 229
           F+    L   P   DVY C VEH  L  P++  W   + S   +          +  G+ 
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESAQSK----------MLSGIG 236

Query: 230 GIIIGTIFIIKGL 242
           G ++G IF+  GL
Sbjct: 237 GFVLGLIFLGLGL 249


>gi|239740918 PREDICTED: similar to major histocompatibility
           complex, class II, DQ beta 1 isoform 1 [Homo sapiens]
          Length = 281

 Score = 72.0 bits (175), Expect = 5e-13
 Identities = 41/133 (30%), Positives = 59/133 (44%), Gaps = 10/133 (7%)

Query: 110 VPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHL 169
           V P VT+  +    L   N+L+C +  F P  + V W RN +  TTGV  T  +   D  
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNDQEETTGVVSTPLIRNGDWT 186

Query: 170 FRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLV 229
           F+    L   P   DVY C VEH  L  P++  W   + S   +          +  G+ 
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQNPIIVEWRAQSESAQSK----------MLSGIG 236

Query: 230 GIIIGTIFIIKGL 242
           G ++G IF+  GL
Sbjct: 237 GFVLGLIFLGLGL 249


>gi|239758095 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 [Homo sapiens]
          Length = 281

 Score = 71.6 bits (174), Expect = 6e-13
 Identities = 41/133 (30%), Positives = 58/133 (43%), Gaps = 10/133 (7%)

Query: 110 VPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHL 169
           V P VT+  +    L   N+L+C +  F P  + V W RNG+  T GV  T  +   D  
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTPLIRNGDWT 186

Query: 170 FRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLV 229
           F+    L   P   DVY C VEH  L  P+   W   + S   +          +  G+ 
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSK----------MLSGIG 236

Query: 230 GIIIGTIFIIKGL 242
           G ++G IF+  GL
Sbjct: 237 GFVLGLIFLGLGL 249


>gi|239740749 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 [Homo sapiens]
          Length = 281

 Score = 71.6 bits (174), Expect = 6e-13
 Identities = 41/133 (30%), Positives = 58/133 (43%), Gaps = 10/133 (7%)

Query: 110 VPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPREDHL 169
           V P VT+  +    L   N+L+C +  F P  + V W RNG+  T GV  T  +   D  
Sbjct: 127 VEPTVTISPSRTEALNHHNLLVCSVTDFYPAQIKVRWFRNGQEETAGVVSTPLIRNGDWT 186

Query: 170 FRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCALGLTVGLV 229
           F+    L   P   DVY C VEH  L  P+   W   + S   +          +  G+ 
Sbjct: 187 FQILVMLEMTPQRGDVYTCHVEHPSLQSPITVEWRAQSESAQSK----------MLSGIG 236

Query: 230 GIIIGTIFIIKGL 242
           G ++G IF+  GL
Sbjct: 237 GFVLGLIFLGLGL 249


>gi|239748820 PREDICTED: hypothetical protein XP_002346811 [Homo
           sapiens]
          Length = 266

 Score = 71.2 bits (173), Expect = 8e-13
 Identities = 41/140 (29%), Positives = 66/140 (47%), Gaps = 10/140 (7%)

Query: 103 NYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVF 162
           ++T    V P+VTV  +    L+  N+L+C +  F P  + V W RNG+   TGV  T  
Sbjct: 117 SFTVQRRVHPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGL 176

Query: 163 LPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCAL 222
           +   D  F+    L  +P + +VY C+VEH  +  PL   W   + S   +         
Sbjct: 177 IHNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSK--------- 227

Query: 223 GLTVGLVGIIIGTIFIIKGL 242
            +  G+ G ++G +F+  GL
Sbjct: 228 -MLSGVGGFVLGLLFLGAGL 246


>gi|239740859 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 1 [Homo sapiens]
          Length = 267

 Score = 71.2 bits (173), Expect = 8e-13
 Identities = 41/140 (29%), Positives = 66/140 (47%), Gaps = 10/140 (7%)

Query: 103 NYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVF 162
           ++T    V P+VTV  +    L+  N+L+C +  F P  + V W RNG+   TGV  T  
Sbjct: 118 SFTVQRRVHPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGL 177

Query: 163 LPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCAL 222
           +   D  F+    L  +P + +VY C+VEH  +  PL   W   + S   +         
Sbjct: 178 IHNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSK--------- 228

Query: 223 GLTVGLVGIIIGTIFIIKGL 242
            +  G+ G ++G +F+  GL
Sbjct: 229 -MLSGVGGFVLGLLFLGAGL 247


>gi|239740857 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 2 [Homo sapiens]
          Length = 266

 Score = 71.2 bits (173), Expect = 8e-13
 Identities = 41/140 (29%), Positives = 66/140 (47%), Gaps = 10/140 (7%)

Query: 103 NYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVF 162
           ++T    V P+VTV  +    L+  N+L+C +  F P  + V W RNG+   TGV  T  
Sbjct: 117 SFTVQRRVHPKVTVYPSKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKTGVVSTGL 176

Query: 163 LPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCAL 222
           +   D  F+    L  +P + +VY C+VEH  +  PL   W   + S   +         
Sbjct: 177 IHNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEWRARSESAQSK--------- 227

Query: 223 GLTVGLVGIIIGTIFIIKGL 242
            +  G+ G ++G +F+  GL
Sbjct: 228 -MLSGVGGFVLGLLFLGAGL 246


>gi|24797076 major histocompatibility complex, class II, DP beta 1
           precursor [Homo sapiens]
          Length = 258

 Score = 70.9 bits (172), Expect = 1e-12
 Identities = 59/189 (31%), Positives = 82/189 (43%), Gaps = 22/189 (11%)

Query: 67  VWRLEEFGRFAS----FEAQGALANIAVDKANLE---IMTKRS--------NYT---PIT 108
           ++  EEF RF S    F A   L   A +  N +   +  KR+        NY    P+T
Sbjct: 58  IYNREEFARFDSDVGEFRAVTELGRPAAEYWNSQKDILEEKRAVPDRMCRHNYELGGPMT 117

Query: 109 ---NVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVFLPR 165
               V P V V  +    L+  N+L+C +  F P  + V W  NG+  T GV  T  +  
Sbjct: 118 LQRRVQPRVNVSPSKKGPLQHHNLLVCHVTDFYPGSIQVRWFLNGQEETAGVVSTNLIRN 177

Query: 166 EDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPET-TENVVCALGL 224
            D  F+    L   P   DVY C+VEH  LD P+   W+  + S   +T T      LGL
Sbjct: 178 GDWTFQILVMLEMTPQQGDVYTCQVEHTSLDSPVTVEWKAQSDSARSKTLTGAGGFVLGL 237

Query: 225 TVGLVGIII 233
            +  VGI +
Sbjct: 238 IICGVGIFM 246


>gi|52630344 major histocompatibility complex, class II, DR beta 4
           precursor [Homo sapiens]
          Length = 266

 Score = 70.5 bits (171), Expect = 1e-12
 Identities = 41/140 (29%), Positives = 69/140 (49%), Gaps = 10/140 (7%)

Query: 103 NYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVF 162
           ++T    V P+VTV  +    L+  N+L+C ++ F P  + V W RNG+    GV  T  
Sbjct: 117 SFTVQRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGL 176

Query: 163 LPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCAL 222
           +   D  F+    L  +P + +VY C+VEH  +  PL   W     S   E+ ++ + + 
Sbjct: 177 IQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQW-----SARSESAQSKMLS- 230

Query: 223 GLTVGLVGIIIGTIFIIKGL 242
               G+ G ++G +F+  GL
Sbjct: 231 ----GVGGFVLGLLFLGTGL 246


>gi|239758090 PREDICTED: major histocompatibility complex, class II,
           DR beta 4 [Homo sapiens]
          Length = 278

 Score = 70.5 bits (171), Expect = 1e-12
 Identities = 41/140 (29%), Positives = 69/140 (49%), Gaps = 10/140 (7%)

Query: 103 NYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVF 162
           ++T    V P+VTV  +    L+  N+L+C ++ F P  + V W RNG+    GV  T  
Sbjct: 129 SFTVQRRVQPKVTVYPSKTQPLQHHNLLVCSVNGFYPGSIEVRWFRNGQEEKAGVVSTGL 188

Query: 163 LPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCAL 222
           +   D  F+    L  +P + +VY C+VEH  +  PL   W     S   E+ ++ + + 
Sbjct: 189 IQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSMMSPLTVQW-----SARSESAQSKMLS- 242

Query: 223 GLTVGLVGIIIGTIFIIKGL 242
               G+ G ++G +F+  GL
Sbjct: 243 ----GVGGFVLGLLFLGTGL 258


>gi|169168591 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 5 isoform 1 [Homo sapiens]
          Length = 261

 Score = 69.3 bits (168), Expect = 3e-12
 Identities = 62/226 (27%), Positives = 88/226 (38%), Gaps = 35/226 (15%)

Query: 42  DQSGEFMFDFDGDEIFHVDMAKKETVWRL----EEFGRFAS----FEAQGALANIAVDKA 93
           D   +F+F F G   F     +   V R     EE+ RF S    + A   L   A +  
Sbjct: 34  DSPEDFVFQFKGMCYFTNGTERVRGVTRYIYNREEYARFDSDVGVYRAVTPLGPPAAEYW 93

Query: 94  NL--EIMTK---------RSNY------TPITNVPPEVTVLTNSPVELREPNVLICFIDK 136
           N   E++ +         R NY      T    V P VT+  +    L   N+L+C +  
Sbjct: 94  NSQKEVLERTRASVDTVCRHNYQLELRTTLQRRVEPTVTISPSRTEALNHHNLLVCSVTD 153

Query: 137 FTPPVVNVTWLRNGKPVTTGVSETVFLPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLD 196
           F P  + V W RN +  T GV  T  +   D  F+    L   P   DVY C VEH  L 
Sbjct: 154 FYPAQIKVRWFRNDQEETAGVVSTPLIRNGDWTFQILVMLEMTPQRGDVYTCHVEHPSLQ 213

Query: 197 EPLLKHWEFDAPSPLPETTENVVCALGLTVGLVGIIIGTIFIIKGL 242
            P+   W   + S   +          +  G+ G ++G IF+  GL
Sbjct: 214 SPITVEWRAQSESAQSK----------MLSGIGGFVLGLIFLGLGL 249


>gi|239748785 PREDICTED: similar to HLA class II histocompatibility
           antigen, DRB1-9 beta chain [Homo sapiens]
          Length = 266

 Score = 69.3 bits (168), Expect = 3e-12
 Identities = 41/140 (29%), Positives = 64/140 (45%), Gaps = 10/140 (7%)

Query: 103 NYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVF 162
           ++T    V PEVTV       L+  N+L+C +  F P  + V W RNG+    GV  T  
Sbjct: 117 SFTVQRRVHPEVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGL 176

Query: 163 LPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCAL 222
           +   D  F+    L  +P + +VY C+VEH  +  PL   W   + S   +         
Sbjct: 177 IQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVMSPLTVEWRARSESAQSK--------- 227

Query: 223 GLTVGLVGIIIGTIFIIKGL 242
            +  G+ G ++G +F+  GL
Sbjct: 228 -MLSGVGGFVLGLLFLGAGL 246


>gi|239740855 PREDICTED: similar to major histocompatibility
           complex, class II, DR beta 3 isoform 1 [Homo sapiens]
          Length = 267

 Score = 69.3 bits (168), Expect = 3e-12
 Identities = 41/140 (29%), Positives = 67/140 (47%), Gaps = 10/140 (7%)

Query: 103 NYTPITNVPPEVTVLTNSPVELREPNVLICFIDKFTPPVVNVTWLRNGKPVTTGVSETVF 162
           ++T    V P+VTV       L+  N+L+C +  F P  + V W RNG+    GV  T  
Sbjct: 118 SFTVQRRVHPQVTVYPAKTQPLQHHNLLVCSVSGFYPGSIEVRWFRNGQEEKAGVVSTGL 177

Query: 163 LPREDHLFRKFHYLPFLPSTEDVYDCRVEHWGLDEPLLKHWEFDAPSPLPETTENVVCAL 222
           +   D  F+    L  +P + +VY C+VEH  +  PL   W     S   E+ ++ + + 
Sbjct: 178 IQNGDWTFQTLVMLETVPRSGEVYTCQVEHPSVTSPLTVEW-----SARSESAQSKMLS- 231

Query: 223 GLTVGLVGIIIGTIFIIKGL 242
               G+ G ++G +F+  GL
Sbjct: 232 ----GVGGFVLGLLFLGAGL 247


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.140    0.431 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,226,282
Number of Sequences: 37866
Number of extensions: 486480
Number of successful extensions: 1168
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 79
Number of HSP's successfully gapped in prelim test: 43
Number of HSP's that attempted gapping in prelim test: 1019
Number of HSP's gapped (non-prelim): 206
length of query: 254
length of database: 18,247,518
effective HSP length: 100
effective length of query: 154
effective length of database: 14,460,918
effective search space: 2226981372
effective search space used: 2226981372
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.