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Search of human proteins with 4885225
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo
sapiens]
(656 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo sap... 1404 0.0
gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo s... 1397 0.0
gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo s... 1391 0.0
gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo s... 1074 0.0
gi|253970506 Ewing sarcoma breakpoint region 1 isoform 5 [Homo s... 679 0.0
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 457 e-128
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] 335 8e-92
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] 331 1e-90
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 108 2e-23
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 98 2e-20
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 93 7e-19
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 93 7e-19
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 93 7e-19
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 93 9e-19
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 91 3e-18
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 91 3e-18
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 91 3e-18
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 91 3e-18
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 90 7e-18
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 90 7e-18
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 88 3e-17
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 87 5e-17
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 87 6e-17
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 84 5e-16
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s... 83 7e-16
gi|48762934 alpha 2 type I collagen [Homo sapiens] 82 2e-15
gi|153252068 testes-specific heterogenous nuclear ribonucleoprot... 82 2e-15
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s... 81 3e-15
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 81 3e-15
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 81 3e-15
>gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo
sapiens]
Length = 656
Score = 1404 bits (3633), Expect = 0.0
Identities = 656/656 (100%), Positives = 656/656 (100%)
Query: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 60
MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT
Sbjct: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 60
Query: 61 YGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT 120
YGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT
Sbjct: 61 YGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT 120
Query: 121 QPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYP 180
QPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYP
Sbjct: 121 QPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYP 180
Query: 181 MQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY 240
MQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY
Sbjct: 181 MQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY 240
Query: 241 PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR 300
PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR
Sbjct: 241 PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR 300
Query: 301 GRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN 360
GRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN
Sbjct: 301 GRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN 360
Query: 361 SAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDP 420
SAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDP
Sbjct: 361 SAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDP 420
Query: 421 PTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGP 480
PTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGP
Sbjct: 421 PTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGP 480
Query: 481 GGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTEC 540
GGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTEC
Sbjct: 481 GGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTEC 540
Query: 541 NQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFR 600
NQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFR
Sbjct: 541 NQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFR 600
Query: 601 GGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY 656
GGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY
Sbjct: 601 GGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY 656
>gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo
sapiens]
Length = 655
Score = 1397 bits (3617), Expect = 0.0
Identities = 655/656 (99%), Positives = 655/656 (99%), Gaps = 1/656 (0%)
Query: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 60
MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT
Sbjct: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 60
Query: 61 YGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT 120
YGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT
Sbjct: 61 YGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT 120
Query: 121 QPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYP 180
QPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYP
Sbjct: 121 QPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYP 180
Query: 181 MQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY 240
MQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY
Sbjct: 181 MQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY 240
Query: 241 PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR 300
PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR
Sbjct: 241 PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR 300
Query: 301 GRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN 360
GRGRGGFDRGGMSRGGRGGGRGGMG AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN
Sbjct: 301 GRGRGGFDRGGMSRGGRGGGRGGMG-AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN 359
Query: 361 SAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDP 420
SAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDP
Sbjct: 360 SAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDP 419
Query: 421 PTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGP 480
PTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGP
Sbjct: 420 PTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGP 479
Query: 481 GGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTEC 540
GGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTEC
Sbjct: 480 GGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTEC 539
Query: 541 NQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFR 600
NQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFR
Sbjct: 540 NQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFR 599
Query: 601 GGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY 656
GGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY
Sbjct: 600 GGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY 655
>gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo
sapiens]
Length = 661
Score = 1391 bits (3600), Expect = 0.0
Identities = 655/662 (98%), Positives = 655/662 (98%), Gaps = 7/662 (1%)
Query: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 60
MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT
Sbjct: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 60
Query: 61 YGQTAYATSYGQPPT------GYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAA 114
YGQTAYATSYGQPPT GYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAA
Sbjct: 61 YGQTAYATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAA 120
Query: 115 QSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQ 174
QSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQ
Sbjct: 121 QSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQ 180
Query: 175 VPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQ 234
VPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQ
Sbjct: 181 VPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQ 240
Query: 235 QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSM 294
QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSM
Sbjct: 241 QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSM 300
Query: 295 SGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDP 354
SGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG AGERGGFNKPGGPMDEGPDLDLGPPVDP
Sbjct: 301 SGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG-AGERGGFNKPGGPMDEGPDLDLGPPVDP 359
Query: 355 DEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDAT 414
DEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDAT
Sbjct: 360 DEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDAT 419
Query: 415 VSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGP 474
VSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGP
Sbjct: 420 VSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGP 479
Query: 475 GGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNF 534
GGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNF
Sbjct: 480 GGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNF 539
Query: 535 AWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGG 594
AWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGG
Sbjct: 540 AWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGG 599
Query: 595 DRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDR 654
DRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDR
Sbjct: 600 DRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDR 659
Query: 655 PY 656
PY
Sbjct: 660 PY 661
>gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo
sapiens]
Length = 600
Score = 1074 bits (2777), Expect = 0.0
Identities = 532/661 (80%), Positives = 548/661 (82%), Gaps = 66/661 (9%)
Query: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 60
MASTDYSTYSQAAAQQGYSAYTAQP TQ Y AQTT
Sbjct: 1 MASTDYSTYSQAAAQQGYSAYTAQP-------TQGY------------------AQTTQA 35
Query: 61 YGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT 120
YGQ +Y T Y QP + T T A+Y Q+AY T
Sbjct: 36 YGQQSYGT-----------------YGQPTD---------VSYTQAQTTATYG-QTAYAT 68
Query: 121 QPAYPAYGQQPAA-TAPTRPQDGNKPTETSQPQSSTGGYNQPS--LGYGQSNYSYPQVPG 177
+YGQ P T PT PQ ++P + TG Y+ + + Q++Y+ G
Sbjct: 69 -----SYGQPPTGYTTPTAPQAYSQPVQGY----GTGAYDTTTATVTTTQASYAAQSAYG 119
Query: 178 SYPMQPVTA--PPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQ 235
+ P P P + PTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQ
Sbjct: 120 TQPAYPAYGQQPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQ 179
Query: 236 PPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMS 295
PPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMS
Sbjct: 180 PPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMS 239
Query: 296 GPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPD 355
GPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPD
Sbjct: 240 GPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPD 299
Query: 356 EDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATV 415
EDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATV
Sbjct: 300 EDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATV 359
Query: 416 SYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPG 475
SYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPG
Sbjct: 360 SYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPG 419
Query: 476 GPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFA 535
GPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFA
Sbjct: 420 GPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFA 479
Query: 536 WRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGD 595
WRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGD
Sbjct: 480 WRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGD 539
Query: 596 RGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRP 655
RGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRP
Sbjct: 540 RGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRP 599
Query: 656 Y 656
Y
Sbjct: 600 Y 600
>gi|253970506 Ewing sarcoma breakpoint region 1 isoform 5 [Homo
sapiens]
Length = 354
Score = 679 bits (1753), Expect = 0.0
Identities = 326/329 (99%), Positives = 326/329 (99%)
Query: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 60
MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT
Sbjct: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 60
Query: 61 YGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT 120
YGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT
Sbjct: 61 YGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT 120
Query: 121 QPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYP 180
QPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYP
Sbjct: 121 QPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYP 180
Query: 181 MQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY 240
MQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY
Sbjct: 181 MQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY 240
Query: 241 PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR 300
PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR
Sbjct: 241 PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR 300
Query: 301 GRGRGGFDRGGMSRGGRGGGRGGMGSAGE 329
GRGRGGFDRGGMSRGGRGGGRGGMG E
Sbjct: 301 GRGRGGFDRGGMSRGGRGGGRGGMGLQSE 329
Score = 47.8 bits (112), Expect = 3e-05
Identities = 93/359 (25%), Positives = 134/359 (37%), Gaps = 71/359 (19%)
Query: 182 QPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPS--SYGQQ---SSYGQQS---SYG 233
Q +A + P Y+ T +Y Q SY TYGQP+ SY Q ++YGQ + SYG
Sbjct: 16 QGYSAYTAQPTQGYAQTTQ-AYGQQSYG---TYGQPTDVSYTQAQTTATYGQTAYATSYG 71
Query: 234 QQPPTSYP----PQ----------TGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYG 279
Q PPT Y PQ TG+Y + + +SY QS++ + YG
Sbjct: 72 Q-PPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGTQ--PAYPAYG 128
Query: 280 QESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGP 339
Q+ + P + + P + + GG ++ G G+ G + P P
Sbjct: 129 QQPAA-TAPTRPQDGNKPTETSQPQSS--TGGYNQPSLGYGQSNYSYPQVPGSY--PMQP 183
Query: 340 MDEGPDLDLGPPVDPDEDSDNSAIYVQG-LNDSVTLDDLADFFKQCGVVKMNKRTGQPMI 398
+ P PP S Y Q + T + + +Q + + QP
Sbjct: 184 VTAPPSY---PPTSYSSTQPTS--YDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQP-- 236
Query: 399 HIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGL 458
T P T SY P+ + Q S + ++ +SM G+
Sbjct: 237 ------PTSYPP--QTGSYSQAPSQYSQ---------QSSSYGQQSSFRQDHPSSM--GV 277
Query: 459 PPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGG-DRGGFPPRGPRGSRGNPSGGGNVQ 516
+E G GPG GP R GRGG DRGG RG RG GG +Q
Sbjct: 278 YGQESGGF-----SGPGENRSMSGPDNRGRGRGGFDRGGM----SRGGRGGGRGGMGLQ 327
Score = 42.7 bits (99), Expect = 0.001
Identities = 24/43 (55%), Positives = 25/43 (58%), Gaps = 4/43 (9%)
Query: 556 FPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGG 598
F PG +R GP GRGG DR GGM RGGRGG RGG
Sbjct: 285 FSGPGENRSMSGPDNRGRGRGG-FDR---GGMSRGGRGGGRGG 323
Score = 36.2 bits (82), Expect = 0.098
Identities = 22/47 (46%), Positives = 22/47 (46%), Gaps = 1/47 (2%)
Query: 566 GGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGF-RGGRGMDRGGFG 611
G G G G GP RG G DRGG RGGRG RGG G
Sbjct: 279 GQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG 325
Score = 30.8 bits (68), Expect = 4.1
Identities = 24/52 (46%), Positives = 27/52 (51%), Gaps = 3/52 (5%)
Query: 590 GGRGGDRGGFRGGRGMDRGGFGGGRRG-GPGGPPGPLMEQMGGRRGGRGGPG 640
G G + GGF G G +R G RG G GG M + GGR GGRGG G
Sbjct: 276 GVYGQESGGF-SGPGENRSMSGPDNRGRGRGGFDRGGMSR-GGRGGGRGGMG 325
Score = 30.4 bits (67), Expect = 5.4
Identities = 21/39 (53%), Positives = 21/39 (53%), Gaps = 3/39 (7%)
Query: 583 GPGGMFRGGRGGDRGGFRGGRGMDRGGFG-GGRRGGPGG 620
GPG R G D G RG G DRGG GGR GG GG
Sbjct: 287 GPGEN-RSMSGPDNRG-RGRGGFDRGGMSRGGRGGGRGG 323
>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
[Homo sapiens]
Length = 526
Score = 457 bits (1177), Expect = e-128
Identities = 300/664 (45%), Positives = 360/664 (54%), Gaps = 146/664 (21%)
Query: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQ-TTQAYGQQSYGTYGQPTDVSYTQAQTTA 59
MAS DY+ A Q Y AY QP QGY+Q ++Q YGQQSY Y Q TD T+
Sbjct: 1 MASNDYTQQ----ATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTD--------TS 48
Query: 60 TYGQTAYATSYGQPP-TGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAY 118
YGQ++Y+ SYGQ TGY T + PQ Y GYG +S ++QS+Y
Sbjct: 49 GYGQSSYS-SYGQSQNTGYGTQSTPQGYGS-TGGYG---------------SSQSSQSSY 91
Query: 119 GTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGS 178
G Q +YP YGQQPA P S++G Y S S+Y PQ GS
Sbjct: 92 GQQSSYPGYGQQPA------------------PSSTSGSYGSSS---QSSSYGQPQ-SGS 129
Query: 179 YPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPT 238
Y QP SY Q SY QQ +Y P YGQQ+ Y S G
Sbjct: 130 YSQQP----------SYGG------QQQSYGQQQSYNPPQGYGQQNQYNSSSGGGGGGGG 173
Query: 239 SYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPD 298
G+Y Q S S S G + Q G YGQ+ G G R SG
Sbjct: 174 G-----GNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRG----GRGRGGSG-G 223
Query: 299 NRGRGRGGFDR--GGMSRGGRGGGRGGMGSAG--ERGGFNKPGGPMDEGPDLDLGPPVDP 354
G G GG++R GG GRGGGRGG G G +RGGFNK GGP D+G D
Sbjct: 224 GGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHD-----SE 278
Query: 355 DEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDAT 414
++SDN+ I+VQGL ++VT++ +AD+FKQ G++K NK+TGQPMI++Y D+ETGK KG+AT
Sbjct: 279 QDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQPMINLYTDRETGKLKGEAT 338
Query: 415 VSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGP 474
VS++DPP+AKAA++WFDGK+F G+ +KVS A ++ N RGG R GRG RGGP
Sbjct: 339 VSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFN--RGGGNGRGGRG-----RGGP 391
Query: 475 GGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNF 534
G GG GG G GG RGGFP G GGG Q RAGDW+CPNP C N NF
Sbjct: 392 MGRGGYGGG----GSGGGGRGGFPSGG---------GGGGGQQRAGDWKCPNPTCENMNF 438
Query: 535 AWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGG 594
+WR ECNQCKAPKP+G PG GGPGG G G G RGGRGG
Sbjct: 439 SWRNECNQCKAPKPDG--------PG-----GGPGGSHMG-------GNYGDDRRGGRGG 478
Query: 595 -DRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMD-KGEHRQERR 652
DRGG+R GRG DRGGF GGR GG RGG GPGKMD +GEHRQ+RR
Sbjct: 479 YDRGGYR-GRGGDRGGFRGGRGGGD--------------RGG-FGPGKMDSRGEHRQDRR 522
Query: 653 DRPY 656
+RPY
Sbjct: 523 ERPY 526
>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
Length = 592
Score = 335 bits (859), Expect = 8e-92
Identities = 228/554 (41%), Positives = 283/554 (51%), Gaps = 96/554 (17%)
Query: 119 GTQPAYPAYGQ---QPAATAPTRPQDGNKPTETSQPQSSTG--GYNQPSLGYGQSNYSYP 173
G Q +Y YG Q A + T++S Q+ +G Y Q GY QS Y
Sbjct: 12 GEQQSYSTYGNPGSQGYGQASQSYSGYGQTTDSSYGQNYSGYSSYGQSQSGYSQSYGGYE 71
Query: 174 -QVPGSYPMQPVTAPPSYPPTSYSSTQ---PTSYDQSSYSQQNTYGQPSSYGQ-QSSYGQ 228
Q SY QP S +Q SYDQ Y QQ++Y Q S Y Q Q SY +
Sbjct: 72 NQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQGSYDE 131
Query: 229 QSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGP 288
QS+Y QQ SYSQ Y Q +Y + QD + YG+++ G+ G
Sbjct: 132 QSNYDQQHD--------SYSQNQQSYHSQRENYSHHT---QDDRRDVSRYGEDNRGYGG- 179
Query: 289 GENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDL 348
S G GRGRGG+D+ G RG G GG +RGGF GG D GP D
Sbjct: 180 ----SQGG----GRGRGGYDKDG--RGPMTGSSGG-----DRGGFKNFGGHRDYGPRTDA 224
Query: 349 GPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGK 408
D +SDN+ I+VQGL + V+ D + +FFKQ G++K NK+TG+PMI++Y DK+TGK
Sbjct: 225 DSESD---NSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTDKDTGK 281
Query: 409 PKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPP 468
PKG+ATVS++DPP+AKAA++WFDGK+F G+ +KVS A ++P MRGG
Sbjct: 282 PKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEF--MRGG----------- 328
Query: 469 PLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPG 528
G GG GR G RG RGGF RG G+P ++GDW CPNP
Sbjct: 329 ---------GSGGGRRGRGGYRG--RGGFQGRG-----GDP--------KSGDWVCPNPS 364
Query: 529 CGNQNFAWRTECNQCKAPKPEGFLPP-------PFPPPGGDRGRGGPGGMRGGRGGLMDR 581
CGN NFA R CNQC P+PE P + G RGRGG GG RGG GG
Sbjct: 365 CGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYGGDRSG 424
Query: 582 GGPGG--MFRGGRGGDRGGFRGGRGMDR--GGFGGGRRGGPGGPPGPLMEQMGGRRGGRG 637
GG GG GG GDR G GG G DR GG+GG R GG GG G GG G RG
Sbjct: 425 GGYGGDRSSGGGYSGDRSG--GGYGGDRSGGGYGGDRGGGYGGDRG------GGYGGDRG 476
Query: 638 GPGKMDKGEHRQER 651
G D+G + +R
Sbjct: 477 GGYGGDRGGYGGDR 490
Score = 81.3 bits (199), Expect = 3e-15
Identities = 75/201 (37%), Positives = 82/201 (40%), Gaps = 61/201 (30%)
Query: 456 GGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNV 515
GG G G GG GG G GG G GG GGDRGG G RG G GG
Sbjct: 453 GGYGGDRGGGYGGDRGGGYGGDRG-GGYGGDRGGYGGDRGG-GYGGDRGGYGGDRGG--- 507
Query: 516 QHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGR 575
GD G G + GGDR RGG GG RGG
Sbjct: 508 --YGGD----RGGYGGDRGGY-----------------------GGDRSRGGYGGDRGGG 538
Query: 576 GGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGG 635
G GG GG GGDR G GG G DRGG GG RGG GG +MGGR
Sbjct: 539 SGY------GGDRSGGYGGDRSG--GGYGGDRGGGYGGDRGGYGG-------KMGGR--- 580
Query: 636 RGGPGKMDKGEHRQERRDRPY 656
++R ++R+RPY
Sbjct: 581 ---------NDYRNDQRNRPY 592
Score = 54.7 bits (130), Expect = 3e-07
Identities = 55/164 (33%), Positives = 62/164 (37%), Gaps = 55/164 (33%)
Query: 455 RGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGN 514
RGG G G RGG GG G G G GG GGDRGG+ RG G GGG+
Sbjct: 483 RGGYGGDRGGGYGGD-RGGYGGDRGGYG--GDRGGYGGDRGGYGGDRSRGGYGGDRGGGS 539
Query: 515 VQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGG 574
G+ GGDR GG GG R G
Sbjct: 540 -----------------------------------GY--------GGDRS-GGYGGDRSG 555
Query: 575 RGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGP 618
GG GG GG GGDRGG+ GG+ R + +R P
Sbjct: 556 -------GGYGGDRGGGYGGDRGGY-GGKMGGRNDYRNDQRNRP 591
Score = 49.3 bits (116), Expect = 1e-05
Identities = 38/105 (36%), Positives = 44/105 (41%), Gaps = 5/105 (4%)
Query: 227 GQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYG-QQSSFRQDHPSSMGVYGQESGGF 285
G + YG Y G Y Y YG + + D S G YG + GG
Sbjct: 481 GDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDR--SRGGYGGDRGGG 538
Query: 286 SGPGENRSMS-GPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGE 329
SG G +RS G D G G GG DRGG G RGG G MG +
Sbjct: 539 SGYGGDRSGGYGGDRSGGGYGG-DRGGGYGGDRGGYGGKMGGRND 582
Score = 47.8 bits (112), Expect = 3e-05
Identities = 39/116 (33%), Positives = 44/116 (37%), Gaps = 10/116 (8%)
Query: 232 YGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGE 290
YG Y G Y Y YG R + G YG + GG+ G
Sbjct: 471 YGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGD---RGGYGGDRGGYGGDRGGYGGDRS 527
Query: 291 NRSMSGPDNRGRGRGGFDRGG----MSRGGRGGGRGGMGSAGERGGF-NKPGGPMD 341
G G G GG GG S GG GG RGG G G+RGG+ K GG D
Sbjct: 528 RGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGG-GYGGDRGGYGGKMGGRND 582
Score = 46.6 bits (109), Expect = 7e-05
Identities = 43/148 (29%), Positives = 60/148 (40%), Gaps = 22/148 (14%)
Query: 209 SQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYS----QQSSSYGQQ 264
S +YGQ S G+Q SY S+YG P + Y QA YS SSYGQ
Sbjct: 2 SDSGSYGQ--SGGEQQSY---STYGN-------PGSQGYGQASQSYSGYGQTTDSSYGQN 49
Query: 265 SSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGG---- 320
S + S Y Q GG+ ++ P N + + G S+GGR
Sbjct: 50 YSGYSSYGQSQSGYSQSYGGYENQKQSSYSQQPYNNQGQQQNMESSG-SQGGRAPSYDQP 108
Query: 321 -RGGMGSAGERGGFNKPGGPMDEGPDLD 347
G S ++ G+++ G DE + D
Sbjct: 109 DYGQQDSYDQQSGYDQHQGSYDEQSNYD 136
Score = 45.8 bits (107), Expect = 1e-04
Identities = 35/70 (50%), Positives = 39/70 (55%), Gaps = 11/70 (15%)
Query: 276 GVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMS--RGGRGGGRGGMGSAGERGGF 333
G YG + GG G G +R G D RG G GG DRGG RGG GG RGG G G+RGG+
Sbjct: 469 GGYGGDRGG--GYGGDRGGYGGD-RGGGYGG-DRGGYGGDRGGYGGDRGGYG--GDRGGY 522
Query: 334 NKPGGPMDEG 343
GG G
Sbjct: 523 ---GGDRSRG 529
Score = 44.3 bits (103), Expect = 4e-04
Identities = 38/88 (43%), Positives = 42/88 (47%), Gaps = 11/88 (12%)
Query: 254 YSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGM- 312
Y SS G S R S G G SGG G G +R +RG G GG DRGG
Sbjct: 427 YGGDRSSGGGYSGDR----SGGGYGGDRSGG--GYGGDRGGGYGGDRGGGYGG-DRGGGY 479
Query: 313 --SRGGRGGGRGGMGSAGERGGFNKPGG 338
RGG GG RGG G G+RGG+ G
Sbjct: 480 GGDRGGYGGDRGG-GYGGDRGGYGGDRG 506
Score = 43.5 bits (101), Expect = 6e-04
Identities = 31/74 (41%), Positives = 37/74 (50%), Gaps = 8/74 (10%)
Query: 276 GVYGQESGGFSGPGENRSMSGPDNRGRG--RGGF--DRGGMS--RGGRGGGRGGMGSAGE 329
G YG + GG+ G + G D G G RGG+ DRGG RGG GG R G G+
Sbjct: 477 GGYGGDRGGYGG--DRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGD 534
Query: 330 RGGFNKPGGPMDEG 343
RGG + GG G
Sbjct: 535 RGGGSGYGGDRSGG 548
Score = 42.7 bits (99), Expect = 0.001
Identities = 31/71 (43%), Positives = 35/71 (49%), Gaps = 8/71 (11%)
Query: 274 SMGVYGQE---SGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRG---GMGSA 327
S G YG + GG+SG G D G G GG DRGG G RGGG G G G
Sbjct: 423 SGGGYGGDRSSGGGYSGDRSGGGYGG-DRSGGGYGG-DRGGGYGGDRGGGYGGDRGGGYG 480
Query: 328 GERGGFNKPGG 338
G+RGG+ G
Sbjct: 481 GDRGGYGGDRG 491
Score = 42.4 bits (98), Expect = 0.001
Identities = 31/68 (45%), Positives = 36/68 (52%), Gaps = 8/68 (11%)
Query: 274 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSR---GGRGGGRGGMGSAGER 330
S G YG + GG G G +R +RG G GG DRGG GG GG RGG G G+R
Sbjct: 451 SGGGYGGDRGG--GYGGDRGGGYGGDRGGGYGG-DRGGYGGDRGGGYGGDRGGYG--GDR 505
Query: 331 GGFNKPGG 338
GG+ G
Sbjct: 506 GGYGGDRG 513
Score = 40.8 bits (94), Expect = 0.004
Identities = 32/74 (43%), Positives = 35/74 (47%), Gaps = 7/74 (9%)
Query: 276 GVYGQESGGFSGP----GENRSMSGPDNRGRGRGGFDRGGMSR--GGRGGGRGGMGSAGE 329
G YG + GG+ G G +R G D R RG G DRGG S G R GG GG S G
Sbjct: 499 GGYGGDRGGYGGDRGGYGGDRGGYGGD-RSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGG 557
Query: 330 RGGFNKPGGPMDEG 343
GG G D G
Sbjct: 558 YGGDRGGGYGGDRG 571
>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
Length = 589
Score = 331 bits (849), Expect = 1e-90
Identities = 229/559 (40%), Positives = 282/559 (50%), Gaps = 101/559 (18%)
Query: 109 QASYAAQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQS 168
Q SY S YG P YGQ ++ G T S + GY+ Y QS
Sbjct: 14 QQSY---STYGN-PGSQGYGQA------SQSYSGYGQTTDSSYGQNYSGYSSYGQSYSQS 63
Query: 169 NYSYP-QVPGSYPMQPVTAPPSYPPTSYSSTQ---PTSYDQSSYSQQNTYGQPSSYGQ-Q 223
Y Q SY QP S +Q SYDQ Y QQ++Y Q S Y Q Q
Sbjct: 64 YGGYENQKQSSYSQQPYNNQGQQQNMESSGSQGGRAPSYDQPDYGQQDSYDQQSGYDQHQ 123
Query: 224 SSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESG 283
SY +QS+Y QQ SYSQ Y Q +Y + QD + YG+++
Sbjct: 124 GSYDEQSNYDQQHD--------SYSQNQQSYHSQRENYSHHT---QDDRRDVSRYGEDNR 172
Query: 284 GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEG 343
G+ G S G GRGRGG+D+ G RG G GG +RGGF GG D G
Sbjct: 173 GYGG-----SQGG----GRGRGGYDKDG--RGPMTGSSGG-----DRGGFKNFGGHRDYG 216
Query: 344 PDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLD 403
P D D +SDN+ I+VQGL + V+ D + +FFKQ G++K NK+TG+PMI++Y D
Sbjct: 217 PRTDADSESD---NSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNKKTGKPMINLYTD 273
Query: 404 KETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREG 463
K+TGKPKG+ATVS++DPP+AKAA++WFDGK+F G+ +KVS A ++P MRGG
Sbjct: 274 KDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEF--MRGG------ 325
Query: 464 RGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQ 523
G GG GR G RG RGGF RG G+P ++GDW
Sbjct: 326 --------------GSGGGRRGRGGYRG--RGGFQGRG-----GDP--------KSGDWV 356
Query: 524 CPNPGCGNQNFAWRTECNQCKAPKPEGFLPP-------PFPPPGGDRGRGGPGGMRGGRG 576
CPNP CGN NFA R CNQC P+PE P + G RGRGG GG RGG G
Sbjct: 357 CPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRGRGGRGGDRGGYG 416
Query: 577 GLMDRGGPGG--MFRGGRGGDRGGFRGGRGMDR--GGFGGGRRGGPGGPPGPLMEQMGGR 632
G GG GG GG GDR G GG G DR GG+GG R GG GG G GG
Sbjct: 417 GDRSGGGYGGDRSSGGGYSGDRSG--GGYGGDRSGGGYGGDRGGGYGGDRG------GGY 468
Query: 633 RGGRGGPGKMDKGEHRQER 651
G RGG D+G + +R
Sbjct: 469 GGDRGGGYGGDRGGYGGDR 487
Score = 81.3 bits (199), Expect = 3e-15
Identities = 75/201 (37%), Positives = 82/201 (40%), Gaps = 61/201 (30%)
Query: 456 GGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNV 515
GG G G GG GG G GG G GG GGDRGG G RG G GG
Sbjct: 450 GGYGGDRGGGYGGDRGGGYGGDRG-GGYGGDRGGYGGDRGG-GYGGDRGGYGGDRGG--- 504
Query: 516 QHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGR 575
GD G G + GGDR RGG GG RGG
Sbjct: 505 --YGGD----RGGYGGDRGGY-----------------------GGDRSRGGYGGDRGGG 535
Query: 576 GGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGG 635
G GG GG GGDR G GG G DRGG GG RGG GG +MGGR
Sbjct: 536 SGY------GGDRSGGYGGDRSG--GGYGGDRGGGYGGDRGGYGG-------KMGGR--- 577
Query: 636 RGGPGKMDKGEHRQERRDRPY 656
++R ++R+RPY
Sbjct: 578 ---------NDYRNDQRNRPY 589
Score = 54.7 bits (130), Expect = 3e-07
Identities = 55/164 (33%), Positives = 62/164 (37%), Gaps = 55/164 (33%)
Query: 455 RGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGN 514
RGG G G RGG GG G G G GG GGDRGG+ RG G GGG+
Sbjct: 480 RGGYGGDRGGGYGGD-RGGYGGDRGGYG--GDRGGYGGDRGGYGGDRSRGGYGGDRGGGS 536
Query: 515 VQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGG 574
G+ GGDR GG GG R G
Sbjct: 537 -----------------------------------GY--------GGDRS-GGYGGDRSG 552
Query: 575 RGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGP 618
GG GG GG GGDRGG+ GG+ R + +R P
Sbjct: 553 -------GGYGGDRGGGYGGDRGGY-GGKMGGRNDYRNDQRNRP 588
Score = 49.3 bits (116), Expect = 1e-05
Identities = 38/105 (36%), Positives = 44/105 (41%), Gaps = 5/105 (4%)
Query: 227 GQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYG-QQSSFRQDHPSSMGVYGQESGGF 285
G + YG Y G Y Y YG + + D S G YG + GG
Sbjct: 478 GDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDR--SRGGYGGDRGGG 535
Query: 286 SGPGENRSMS-GPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGE 329
SG G +RS G D G G GG DRGG G RGG G MG +
Sbjct: 536 SGYGGDRSGGYGGDRSGGGYGG-DRGGGYGGDRGGYGGKMGGRND 579
Score = 47.8 bits (112), Expect = 3e-05
Identities = 39/116 (33%), Positives = 44/116 (37%), Gaps = 10/116 (8%)
Query: 232 YGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGE 290
YG Y G Y Y YG R + G YG + GG+ G
Sbjct: 468 YGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGD---RGGYGGDRGGYGGDRGGYGGDRS 524
Query: 291 NRSMSGPDNRGRGRGGFDRGG----MSRGGRGGGRGGMGSAGERGGF-NKPGGPMD 341
G G G GG GG S GG GG RGG G G+RGG+ K GG D
Sbjct: 525 RGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGG-GYGGDRGGYGGKMGGRND 579
Score = 45.8 bits (107), Expect = 1e-04
Identities = 35/70 (50%), Positives = 39/70 (55%), Gaps = 11/70 (15%)
Query: 276 GVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMS--RGGRGGGRGGMGSAGERGGF 333
G YG + GG G G +R G D RG G GG DRGG RGG GG RGG G G+RGG+
Sbjct: 466 GGYGGDRGG--GYGGDRGGYGGD-RGGGYGG-DRGGYGGDRGGYGGDRGGYG--GDRGGY 519
Query: 334 NKPGGPMDEG 343
GG G
Sbjct: 520 ---GGDRSRG 526
Score = 44.3 bits (103), Expect = 4e-04
Identities = 38/88 (43%), Positives = 42/88 (47%), Gaps = 11/88 (12%)
Query: 254 YSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGM- 312
Y SS G S R S G G SGG G G +R +RG G GG DRGG
Sbjct: 424 YGGDRSSGGGYSGDR----SGGGYGGDRSGG--GYGGDRGGGYGGDRGGGYGG-DRGGGY 476
Query: 313 --SRGGRGGGRGGMGSAGERGGFNKPGG 338
RGG GG RGG G G+RGG+ G
Sbjct: 477 GGDRGGYGGDRGG-GYGGDRGGYGGDRG 503
Score = 43.5 bits (101), Expect = 6e-04
Identities = 31/74 (41%), Positives = 37/74 (50%), Gaps = 8/74 (10%)
Query: 276 GVYGQESGGFSGPGENRSMSGPDNRGRG--RGGF--DRGGMS--RGGRGGGRGGMGSAGE 329
G YG + GG+ G + G D G G RGG+ DRGG RGG GG R G G+
Sbjct: 474 GGYGGDRGGYGG--DRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGD 531
Query: 330 RGGFNKPGGPMDEG 343
RGG + GG G
Sbjct: 532 RGGGSGYGGDRSGG 545
Score = 42.7 bits (99), Expect = 0.001
Identities = 31/71 (43%), Positives = 35/71 (49%), Gaps = 8/71 (11%)
Query: 274 SMGVYGQE---SGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRG---GMGSA 327
S G YG + GG+SG G D G G GG DRGG G RGGG G G G
Sbjct: 420 SGGGYGGDRSSGGGYSGDRSGGGYGG-DRSGGGYGG-DRGGGYGGDRGGGYGGDRGGGYG 477
Query: 328 GERGGFNKPGG 338
G+RGG+ G
Sbjct: 478 GDRGGYGGDRG 488
Score = 42.4 bits (98), Expect = 0.001
Identities = 31/68 (45%), Positives = 36/68 (52%), Gaps = 8/68 (11%)
Query: 274 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSR---GGRGGGRGGMGSAGER 330
S G YG + GG G G +R +RG G GG DRGG GG GG RGG G G+R
Sbjct: 448 SGGGYGGDRGG--GYGGDRGGGYGGDRGGGYGG-DRGGYGGDRGGGYGGDRGGYG--GDR 502
Query: 331 GGFNKPGG 338
GG+ G
Sbjct: 503 GGYGGDRG 510
Score = 40.8 bits (94), Expect = 0.004
Identities = 32/74 (43%), Positives = 35/74 (47%), Gaps = 7/74 (9%)
Query: 276 GVYGQESGGFSGP----GENRSMSGPDNRGRGRGGFDRGGMSR--GGRGGGRGGMGSAGE 329
G YG + GG+ G G +R G D R RG G DRGG S G R GG GG S G
Sbjct: 496 GGYGGDRGGYGGDRGGYGGDRGGYGGD-RSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGG 554
Query: 330 RGGFNKPGGPMDEG 343
GG G D G
Sbjct: 555 YGGDRGGGYGGDRG 568
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 108 bits (270), Expect = 2e-23
Identities = 177/652 (27%), Positives = 213/652 (32%), Gaps = 100/652 (15%)
Query: 62 GQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGTQ 121
GQ S G P + PT PQ YS +YD + A Y +
Sbjct: 127 GQPGSPGSPGPPGICESCPTGPQNYSPQYD-----SYDVKSGVAVGGLAGYPGPAGPPGP 181
Query: 122 PAYPAYGQQPAATAPTRPQDGNKPTETSQ--PQSSTG--GYNQPSLGYGQSNYS-YPQVP 176
P P P + P P P E Q P G G PS G+ S P P
Sbjct: 182 PGPPGTSGHPGS--PGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRP 239
Query: 177 GS--YPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQ 234
G P P P+ P +D + + T G P G+ G+ + G
Sbjct: 240 GERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGET-GAPGLKGENGLPGENGAPGP 298
Query: 235 QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYG--------QESGGFS 286
P P + G P + + + S + P G G E G
Sbjct: 299 MGPRGAPGERGRPG-LPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAG 357
Query: 287 GPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDL 346
PG N P RG G G G G G GE G PG P G
Sbjct: 358 SPGSN---GAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARG 414
Query: 347 DLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKET 406
GP G N + + G+ + G+ D +
Sbjct: 415 PPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGE-------DGKD 467
Query: 407 GKPKGDATVSYEDPPTAKAAVEWFDG----KDFQGSKLKVSLARKKPPMNSMRG--GLPP 460
G P G+ + + F G G K R P RG G P
Sbjct: 468 GSP-GEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAG-ERGAPGPAGPRGAAGEPG 525
Query: 461 REGRGMPPPLRGGPGGPGGPG-----GPMGRMG--GRGGDRGGFPPRGPRGSRGNPSGGG 513
R+G P +RG PG PGGPG GP G G GR G G PRG G G P G
Sbjct: 526 RDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKG 585
Query: 514 NVQHRAGDWQCPNPGC-GNQNFAWRTECNQCKAPKPEGFLPPPFPP----PGGDRGRGGP 568
N + + PG G Q P G P PP PGGD+G GP
Sbjct: 586 NDGAPGKNGERGGPGGPGPQG-----------PPGKNGETGPQGPPGPTGPGGDKGDTGP 634
Query: 569 GGMRG-----GRGGLMDR----------------GGPGGMFRGGRGGDRG--------GF 599
G +G G GG G PGG G G+RG G
Sbjct: 635 PGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGL 694
Query: 600 RGGRGMDRGGFGGGRRGGPGGPPG----PLMEQMGGRRGGRGGPG-KMDKGE 646
RGG G G GG GP GPPG P ++ M G RGG G PG K DKGE
Sbjct: 695 RGGAG-PPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGE 745
Score = 103 bits (257), Expect = 5e-22
Identities = 133/435 (30%), Positives = 162/435 (37%), Gaps = 71/435 (16%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 274
G P G G G + P + G P S G S + P S
Sbjct: 498 GIPGEKGPAGERGAPGPAGPRGAAGEPGRDG-VPGGPGMRGMPGSPGGPGSDGKPGPPGS 556
Query: 275 MGVYGQESGGFSGPGENRSMSGPDNRGR-GRGGFD--RGGMSRGGRGGGRGGMGSAGERG 331
G ESG PG SGP RG+ G GF +G G+ G RGG G G +G
Sbjct: 557 QG----ESGRPGPPGP----SGP--RGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQG 606
Query: 332 GFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNK 391
K G +GP GP D + +QGL + G N
Sbjct: 607 PPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGT------------GGPPGENG 654
Query: 392 RTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPM 451
+ G+P PKGDA P A GK G+ + PP
Sbjct: 655 KPGEP-----------GPKGDA-----GAPGAPG------GKGDAGAP-----GERGPP- 686
Query: 452 NSMRGGLPPREGRGMPPPLRG-GPGGPGGPGGPMGRMG--GRGGDRGGFPPRGPRGSRGN 508
+ G R G G P P G G GP GP G G G G G+RGG GP+G +G
Sbjct: 687 -GLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGE 745
Query: 509 PSGGG--NVQHRAGDWQCPNPGCGNQNFAWRT-ECNQCKAPKPEGFLPPPFPPPGGDRGR 565
P G G V + G + P G A + + + AP G P P G+RG
Sbjct: 746 PGGPGADGVPGKDGP-RGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSP--GERGE 802
Query: 566 GGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPL 625
GP G G G G PGG G G++G GG G GG GP GPPGP
Sbjct: 803 TGPPGPAGFPGAPGQNGEPGGKGERGAPGEKG--EGGPPGVAGPPGG---SGPAGPPGP- 856
Query: 626 MEQMGGRRGGRGGPG 640
+ + G RG GGPG
Sbjct: 857 -QGVKGERGSPGGPG 870
Score = 101 bits (251), Expect = 2e-21
Identities = 150/550 (27%), Positives = 179/550 (32%), Gaps = 82/550 (14%)
Query: 134 TAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPT 193
TAPTRP +G P Q G P + + P PGS P P PP +
Sbjct: 93 TAPTRPPNGQGP------QGPKGDPGPPGIPGRNGDPGIPGQPGS-PGSP--GPPGICES 143
Query: 194 SYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS-QAPS 252
+ Q S SY ++ G G G + +P GS Q P
Sbjct: 144 CPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPP 203
Query: 253 QYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRG-RGRGGFD--R 309
Q+ G PS ESG PGE P +G G GF +
Sbjct: 204 GEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMK 263
Query: 310 GGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLN 369
G GR G +G G+ G +G PG GP G P + A +G N
Sbjct: 264 GHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARG-N 322
Query: 370 DSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEW 429
D D GQP G P T + P AK V
Sbjct: 323 DGARGSD-----------------GQP----------GPPGPPGTAGFPGSPGAKGEVGP 355
Query: 430 FDGKDFQGSK-------LKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPG-----GP 477
G+ + + PP G P +G P + G PG GP
Sbjct: 356 AGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGP 415
Query: 478 GGPGGPMGRMG--------GRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGC 529
GP G G G G+ G +G PRG RG G P G D PG
Sbjct: 416 PGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGA 475
Query: 530 -GNQNFAWRTECNQCKAPK-PEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGM 587
G A + P P G P P G+RG GP G RG G G PGG
Sbjct: 476 NGLPGAAGERGAPGFRGPAGPNGI--PGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGP 533
Query: 588 -FRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQ--MG-------------- 630
RG G G G+ G G R GP GP GP + MG
Sbjct: 534 GMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKN 593
Query: 631 GRRGGRGGPG 640
G RGG GGPG
Sbjct: 594 GERGGPGGPG 603
Score = 96.3 bits (238), Expect = 8e-20
Identities = 147/539 (27%), Positives = 178/539 (33%), Gaps = 122/539 (22%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQ--------------QSSS 260
G P + G + + G + S GQ P PP T + +P + Q
Sbjct: 312 GLPGAAGARGNDGARGSDGQPGPPG-PPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGE 370
Query: 261 YGQQS-SFRQDHPSSMGVYGQESG-------GFSG-PGENRSMSGPDNRGRGRGGFDRGG 311
G Q + Q P G+ G G G G PG + P G RGG
Sbjct: 371 PGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGG 430
Query: 312 MSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGL--- 368
G+ G +G G GERG PG P +G D G P +P + A +G
Sbjct: 431 AGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGF 490
Query: 369 ------NDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPT 422
N A G G+P G P G P
Sbjct: 491 RGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEP-------GRDGVPGGPGMRGMPGSPG 543
Query: 423 AKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRG-----GLPPREGRGMPPPLRGGPGGP 477
+ DGK S P + RG G P +G P G GGP
Sbjct: 544 GPGS----DGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGP 599
Query: 478 GGPG--GPMGRMG-----------GRGGDRGGFPPRGPRGSRGNPSGGGNVQHRA----- 519
GGPG GP G+ G G GGD+G P GP+G +G P GG
Sbjct: 600 GGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEP 659
Query: 520 ---GDWQCPNPGCGNQNFAWRTECNQ---CKAPKPEGFLPPPFP--------PPGGDRGR 565
GD P G + E AP G PP P PPG
Sbjct: 660 GPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAA 719
Query: 566 GGPG--GMRGGRGGLM---------DRGGPGGMFRGGRGGDRG-----------GFRGGR 603
G PG GM G RGGL + GGPG G+ G RG G G +
Sbjct: 720 GTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDK 779
Query: 604 GMDRGGFGG-----GRRGGPG-----GPPGPL-------MEQMGGRRGGRGGPGKMDKG 645
G GG G G RG PG GPPGP G +G RG PG+ +G
Sbjct: 780 G--EGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEG 836
Score = 85.5 bits (210), Expect = 1e-16
Identities = 131/464 (28%), Positives = 161/464 (34%), Gaps = 67/464 (14%)
Query: 215 GQPSSYGQQSS------YGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFR 268
GQP G+ + G + S G++ T PP + AP Q + + +
Sbjct: 774 GQPGDKGEGGAPGLPGIAGPRGSPGERGETG-PPGPAGFPGAPGQNGEPGGKGERGAPGE 832
Query: 269 QDHPSSMGVYGQESG-GFSGP-------GENRSMSGPDNRG----RGRGG--FDRGGMSR 314
+ GV G G G +GP GE S GP G RG G G
Sbjct: 833 KGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGP 892
Query: 315 GGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTL 374
G G G G G G PG P GP D G P E A G + +
Sbjct: 893 PGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAG---QPGEKGSPGAQGPPGAPGPLGI 949
Query: 375 DDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAK-----AAVEW 429
+ G M G P + E+GKP + PP + A
Sbjct: 950 AGITGARGLAGPPGMPGPRGSPGPQ-GVKGESGKPGANGLSGERGPPGPQGLPGLAGTAG 1008
Query: 430 FDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG--GPMGRM 487
G+D G+ L P + GG R G P G PG PG PG GP+G
Sbjct: 1009 EPGRD--GNPGSDGL----PGRDGSPGGKGDRGENGSP----GAPGAPGHPGPPGPVGP- 1057
Query: 488 GGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPK 547
G+ GDRG P GP G+ G AG P P + E
Sbjct: 1058 AGKSGDRGESGPAGPAGAPGP----------AGSRGAPGPQGPRGDKGETGERGAAGIKG 1107
Query: 548 PEGFL----PPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRG 601
GF P P P G +G G G G RG + G PG G G G G RG
Sbjct: 1108 HRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRG 1167
Query: 602 GRGMDRGGFGG----GRRGGPG--GPPGPLMEQMGGRR-GGRGG 638
RG +RG G G+ G PG G PGP +G G GG
Sbjct: 1168 NRG-ERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGG 1210
Score = 84.0 bits (206), Expect = 4e-16
Identities = 140/533 (26%), Positives = 160/533 (30%), Gaps = 97/533 (18%)
Query: 156 GGYNQPSLGYGQSNYSYPQVPGSY-----PMQPVTAPPSYPPTSYSSTQPTSYDQS--SY 208
G P G + P PGS P P + P P P D +
Sbjct: 534 GMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKN 593
Query: 209 SQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFR 268
++ G P G G+ G PT G Q Q G
Sbjct: 594 GERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPG-E 652
Query: 269 QDHPSSMGVYGQESGGFSGPGENRSMSGPDNRG----RGRGGFDRGGMSRGGRGGGRGGM 324
P G G ++G PG P RG G G RGG G GG+G
Sbjct: 653 NGKPGEPGPKG-DAGAPGAPGGKGDAGAPGERGPPGLAGAPGL-RGGAGPPGPEGGKGAA 710
Query: 325 GSAGERGGFNKPG---------GPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLD 375
G G G PG G GP D G P P D +G +
Sbjct: 711 GPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPP 770
Query: 376 DLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDF 435
A Q G G P I P+G E P A F G
Sbjct: 771 GPAG---QPGDKGEGGAPGLPGI--------AGPRGSPGERGETGPPGPAG---FPGAPG 816
Query: 436 QGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGG--PGGPGGPMGRMGGRGGD 493
Q + P G P +G G PP + G PGG P GP GP G G RG
Sbjct: 817 QNGE----------PGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSP 866
Query: 494 RG----GFPPR----GPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKA 545
G GFP GP GS GNP G P+ G
Sbjct: 867 GGPGAAGFPGARGLPGPPGSNGNPGPPG-----------PSGSPGKDG-----------P 904
Query: 546 PKPEGFLPPPFPPP-GGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----GF 599
P P G P P G +G G G +G G G PG + G G RG G
Sbjct: 905 PGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGM 964
Query: 600 RGGRGMDRGGFGGGRRGGPG--------GPPGPL----MEQMGGRRGGRGGPG 640
G RG G G PG GPPGP + G G G PG
Sbjct: 965 PGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPG 1017
Score = 75.9 bits (185), Expect = 1e-13
Identities = 119/436 (27%), Positives = 149/436 (34%), Gaps = 63/436 (14%)
Query: 226 YGQQSSYGQQPPTSYP-PQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGG 284
+G+ + QPPT+ P G Q P G R P G G G
Sbjct: 81 FGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPG-----RNGDPGIPGQPGSP-GS 134
Query: 285 FSGPGENRSM-SGPDNRGRGRGGFD-RGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDE 342
PG S +GP N +D + G++ GG G G G G G G P
Sbjct: 135 PGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSP 194
Query: 343 GPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYL 402
G GPP +P + + G + + G+
Sbjct: 195 GSPGYQGPPGEPGQAGPSGPP------------------GPPGAIGPSGPAGK------- 229
Query: 403 DKETGKPKGDATVSYEDPPTAK--AAVEWFDG----KDFQGSKLKVSLARKKPPMNSMRG 456
D E+G+P PP K A + F G + F G P
Sbjct: 230 DGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGR--NGEKGETGAPGLKGEN 287
Query: 457 GLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGD--RGGFPPRGPRGSRGNPSGGGN 514
GLP G P RG PG G PG P G G RG D RG GP G G G+
Sbjct: 288 GLPGENGAPGPMGPRGAPGERGRPGLP-GAAGARGNDGARGSDGQPGPPGPPGTAGFPGS 346
Query: 515 VQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFL---PPPFPP-----PGGDRGRG 566
+ +PG Q P P+G PP PP PGG +G
Sbjct: 347 PGAKGEVGPAGSPGSNGAP-------GQRGEPGPQGHAGAQGPPGPPGINGSPGG-KGEM 398
Query: 567 GPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGF-RGGRGMDRGGFG-GGRRGGPGGPPGP 624
GP G+ G G + RG PG G G RGG G+ +G G G RG G P P
Sbjct: 399 GPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVP 458
Query: 625 LMEQMGGRRGGRGGPG 640
+ G+ G G PG
Sbjct: 459 GAKGEDGKDGSPGEPG 474
Score = 63.2 bits (152), Expect = 8e-10
Identities = 81/298 (27%), Positives = 102/298 (34%), Gaps = 83/298 (27%)
Query: 409 PKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPP 468
P G+ PPTA +G+ QG K PP G+P R G P
Sbjct: 80 PFGECCAVCPQPPTAPTRPP--NGQGPQGPK-----GDPGPP------GIPGRNG---DP 123
Query: 469 PLRGGPGGPGGPGGP---------------------------MGRMGGRGGDRGGFPPRG 501
+ G PG PG PG P +G + G G G P G
Sbjct: 124 GIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPG 183
Query: 502 PRGSRGNPSGGGNVQH--------RAGDWQCPNP--GCGNQNFAWRT-ECNQCKAPKPEG 550
P G+ G+P G+ + +AG P P G A + E + P G
Sbjct: 184 PPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERG 243
Query: 551 FLPPP-------------------FPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGG 591
PP F G++G G G++G G + G PG M G
Sbjct: 244 LPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRG 303
Query: 592 RGGDRG-----GFRGGRGMDRGGFGGGRRGGPGGPPG----PLMEQMGGRRGGRGGPG 640
G+RG G G RG D G G + GP GPPG P G G G PG
Sbjct: 304 APGERGRPGLPGAAGARGND-GARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPG 360
Score = 61.6 bits (148), Expect = 2e-09
Identities = 69/218 (31%), Positives = 85/218 (38%), Gaps = 59/218 (27%)
Query: 468 PPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNP 527
PP GP GP G GP G + GR GD G P G GS G+P G + CP
Sbjct: 98 PPNGQGPQGPKGDPGPPG-IPGRNGDPG-IP--GQPGSPGSPGPPGICE------SCPT- 146
Query: 528 GCGNQNFAWRTECNQCKA----------PKPEGFLPPPFPP----------------PGG 561
G QN++ + + K+ P P G PP PP P G
Sbjct: 147 --GPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPG 204
Query: 562 DRGRGGPGGMRGGRGGLMDRGGPGGMF----RGGRGGDRG-----GFRGGRGMDRGGFGG 612
+ G+ GP G G G + GP G R GR G+RG G +G G+ GF G
Sbjct: 205 EPGQAGPSGPPGPPGAI-GPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIP--GFPG 261
Query: 613 --------GRRGGPGGPPGPLMEQMGGRRGGRGGPGKM 642
GR G G P ++ G G G PG M
Sbjct: 262 MKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPM 299
Score = 48.1 bits (113), Expect = 2e-05
Identities = 59/222 (26%), Positives = 76/222 (34%), Gaps = 18/222 (8%)
Query: 139 PQDGNKPTETSQPQSSTGGYNQPSLGYGQSNY----SYPQVPGSY----PMQPVTAPPSY 190
P G+ P PQ G P G G + + P PGS P P +P
Sbjct: 844 PPGGSGPAGPPGPQGVKGERGSPG-GPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKD 902
Query: 191 PPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQA 250
P + + GQP G++ S G Q G P TG+ A
Sbjct: 903 GPPGPAGNTGAPGSPGVSGPKGDAGQP---GEKGSPGAQGPPGAPGPLGIAGITGARGLA 959
Query: 251 --PSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFD 308
P + S Q P + G+ G+ G GP ++G GR G +
Sbjct: 960 GPPGMPGPRGSPGPQGVKGESGKPGANGLSGER--GPPGPQGLPGLAGTAGEP-GRDG-N 1015
Query: 309 RGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGP 350
G GR G GG G GE G PG P GP +GP
Sbjct: 1016 PGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGP 1057
Score = 40.4 bits (93), Expect = 0.005
Identities = 58/260 (22%), Positives = 74/260 (28%), Gaps = 31/260 (11%)
Query: 122 PAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPM 181
P P P P P + G QP P PG +
Sbjct: 890 PGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGI 949
Query: 182 QPVTA------PPSYP-PTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQ 234
+T PP P P Q + G+ G Q G + G+
Sbjct: 950 AGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGE 1009
Query: 235 QPPTSYPPQTGSYSQ--APSQYSQQSSSYGQQSSFRQDHPSSMGVYGQ--------ESG- 283
P G + +P + + + HP G G ESG
Sbjct: 1010 PGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGP 1069
Query: 284 ----GFSGPGENRSMSGPDN-RG-------RGRGGFDRGGMSRGGRGGGRGGMGSAGERG 331
G GP +R GP RG RG G +G G G G G AG++G
Sbjct: 1070 AGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGI-KGHRGFPGNPGAPGSPGPAGQQG 1128
Query: 332 GFNKPGGPMDEGPDLDLGPP 351
PG GP GPP
Sbjct: 1129 AIGSPGPAGPRGPVGPSGPP 1148
Score = 40.0 bits (92), Expect = 0.007
Identities = 40/135 (29%), Positives = 45/135 (33%), Gaps = 28/135 (20%)
Query: 524 CPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGG 583
CPNP + C C P PP P G +G GP G+ G G D G
Sbjct: 74 CPNP-----EIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNG---DPGI 125
Query: 584 PGGMFRGGRGGDRG-----------------GFRGGRGMDRGGFGG-GRRGGPGGPPGPL 625
PG G G G + G+ GG G GP GPPGP
Sbjct: 126 PGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGP- 184
Query: 626 MEQMGGRRGGRGGPG 640
G G G PG
Sbjct: 185 -PGTSGHPGSPGSPG 198
Score = 39.7 bits (91), Expect = 0.009
Identities = 58/250 (23%), Positives = 81/250 (32%), Gaps = 27/250 (10%)
Query: 122 PAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPM 181
P P P P+ + P P +TG P + + + P GS
Sbjct: 881 PGPPGSNGNPGPPGPSGSPGKDGPPG---PAGNTGAPGSPGVSGPKGDAGQPGEKGSPGA 937
Query: 182 QPVTAPPSYP-PTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY 240
Q PP P P + + G P G + S G Q G+
Sbjct: 938 Q---GPPGAPGPLGIAGIT---------GARGLAGPPGMPGPRGSPGPQGVKGESGKPGA 985
Query: 241 PPQTGSYSQ-APSQYSQQSSSYGQQSSFRQDHPSSMGVYGQES--GGFSGPGENRSMSGP 297
+G P + + G+ R +P S G+ G++ GG GEN S P
Sbjct: 986 NGLSGERGPPGPQGLPGLAGTAGEPG--RDGNPGSDGLPGRDGSPGGKGDRGENGSPGAP 1043
Query: 298 DNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDED 357
G G + G+ G RG G AG G G GP GP D E
Sbjct: 1044 GAPGHPG---PPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQ---GPRGDKGET 1097
Query: 358 SDNSAIYVQG 367
+ A ++G
Sbjct: 1098 GERGAAGIKG 1107
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 98.2 bits (243), Expect = 2e-20
Identities = 148/552 (26%), Positives = 192/552 (34%), Gaps = 90/552 (16%)
Query: 111 SYAAQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNY 170
++A Q +YG P P+ P+ P PQ G +P G+
Sbjct: 158 NFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEP----GEPGA 213
Query: 171 SYPQVPGSYPMQPVTAPPSYPPTSYSSTQP-------TSYDQSSYSQQNTYGQPSSYGQQ 223
S P P P PP + +P Q + T G P G +
Sbjct: 214 SGPMGPRGPP-----GPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHR 268
Query: 224 SSYGQQSSYGQQPPTSYPPQTGSYSQ--APSQYSQQSSSYGQQSSFRQDHPSSMGVYGQE 281
G + G P + GS + AP Q + G++ R P G G +
Sbjct: 269 GFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLP-GERG--RPGAPGPAGARGND 325
Query: 282 SG-GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPM 340
G +GP +GP GF G + G G +G GS G +G +PG P
Sbjct: 326 GATGAAGPPGPTGPAGPP-------GFP-GAVGAKGEAGPQGPRGSEGPQGVRGEPGPP- 376
Query: 341 DEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHI 400
GP GP +P D A +G N + + F G G P
Sbjct: 377 --GPAGAAGPAGNPGADGQPGA---KGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKG 431
Query: 401 YLDKETGKP--KGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGL 458
E G P KGD E P G++ + AR +P + G
Sbjct: 432 N-SGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRG------ARGEPGPTGLPG-- 482
Query: 459 PPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNVQ 516
PP RGGPG G PG G G +G G+RG P GP+GS G G
Sbjct: 483 --------PPGERGGPGSRGFPGAD-GVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAG 533
Query: 517 HRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRG 576
+PG +P P+G PP P G GR GP G G RG
Sbjct: 534 LPGAKGLTGSPG----------------SPGPDGKTGPP--GPAGQDGRPGPPGPPGARG 575
Query: 577 --GLMDRGGP-GGMFRGGRGGDRG-----GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQ 628
G+M GP G G+ G+RG G G G D G GP GP GP E+
Sbjct: 576 QAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKD----GEAGAQGPPGPAGPAGER 631
Query: 629 MGGRRGGRGGPG 640
G +G G PG
Sbjct: 632 --GEQGPAGSPG 641
Score = 92.0 bits (227), Expect = 2e-18
Identities = 157/593 (26%), Positives = 185/593 (31%), Gaps = 104/593 (17%)
Query: 125 PAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSL--GYGQSNYSYPQVP-GSYPM 181
P +P A P + + T + P TG P G + PQ P GS
Sbjct: 307 PGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGP 366
Query: 182 QPVTAPPSYP-PTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY 240
Q V P P P + + G P G G + G Q P
Sbjct: 367 QGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGP 426
Query: 241 PPQTGSYSQ--APSQYSQQSSSYGQQSSFRQDHPSSMGVYGQ-----ESGGFSGPGENRS 293
P G+ + AP + Q P G G+ E G PG
Sbjct: 427 PGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGE 486
Query: 294 MSGPDNRG----------RGRGGFDRGGMSRGGRGGGRGGMGSAGERG---GFNKPGGPM 340
GP +RG +G G +RG G G G G GE G G P
Sbjct: 487 RGGPGSRGFPGADGVAGPKGPAG-ERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPG 545
Query: 341 DEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHI 400
GPD GPP +D G Q GV+ G
Sbjct: 546 SPGPDGKTGPPGPAGQDGRPGPPGPPGARG------------QAGVMGFPGPKGA----- 588
Query: 401 YLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK----PPMNSMRG 456
G+P PP A QG A ++ P +
Sbjct: 589 -----AGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQ 643
Query: 457 GLPPREGRGMPPPLRGGPGGPGGPG-----GPMGRMGGRG--GDRGGFPPRGPRGSRGNP 509
GLP G PP G PG G PG GP G G RG G+RG P GP G RG
Sbjct: 644 GLPGPAG---PPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGAN 700
Query: 510 SGGGNVQHRAGDWQCPN-PGC----GNQNFAWRTECNQCKAPK-------PEGF------ 551
GN GD P PG G Q PK P+G
Sbjct: 701 GAPGN-DGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGK 759
Query: 552 -----LPPPFPPPG--------GDRGRGGPGGMRGGRGGLMDRGGPG----GMFRGGRGG 594
L P PPG G+ G GP G G RG DRG PG F G G
Sbjct: 760 DGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGA 819
Query: 595 D-RGGFRG--GRGMDRGGFGGGRRGGPGGPPGPL----MEQMGGRRGGRGGPG 640
D + G +G G +G G GP GPPGP+ G RG G PG
Sbjct: 820 DGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPG 872
Score = 88.2 bits (217), Expect = 2e-17
Identities = 124/452 (27%), Positives = 154/452 (34%), Gaps = 71/452 (15%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 274
G P G + G G Q P G+ + AP + + + Q P
Sbjct: 668 GAPGPSGARGERGFPGERGVQGPPGPAGPRGA-NGAPGNDGAKGDAGAPGAPGSQGAPGL 726
Query: 275 MGVYGQE-SGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGF 333
G+ G+ + G GP +R +GP +G G+ G RG G G G
Sbjct: 727 QGMPGERGAAGLPGPKGDRGDAGP-----------KGADGSPGKDGVRGLTGPIGPPGPA 775
Query: 334 NKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRT 393
PG + GP GP D G G
Sbjct: 776 GAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPG---------------PAGFAGPPGAD 820
Query: 394 GQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGK--DFQGSKLKVSLARKKPPM 451
GQP G+P GDA + P A G + K + PP
Sbjct: 821 GQP-------GAKGEP-GDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPG 872
Query: 452 NSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG-----------GDRGGFPPR 500
+ G P GR + PP G GP GP GP G+ GG+G G+ G P
Sbjct: 873 AT---GFPGAAGR-VGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPP 928
Query: 501 GPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPE-GFLPPPFPPP 559
GP G +G+P G AG P P Q A + + E GF P P P
Sbjct: 929 GPAGEKGSPGADGP----AGAPGTPGP----QGIAGQRGVVGLPGQRGERGF--PGLPGP 978
Query: 560 GGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRG- 616
G+ G+ GP G G RG G PG G G G G G G D G RG
Sbjct: 979 SGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGE 1038
Query: 617 -GPGGPPGPLMEQMGGRRGGRGGPGKM-DKGE 646
GP GPPG G G G GK D+GE
Sbjct: 1039 TGPAGPPG--APGAPGAPGPVGPAGKSGDRGE 1068
Score = 83.2 bits (204), Expect = 7e-16
Identities = 106/366 (28%), Positives = 123/366 (33%), Gaps = 70/366 (19%)
Query: 316 GRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLD 375
G G RG G AG G PG P GP GPP P + + G ++ T
Sbjct: 115 GDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGG 174
Query: 376 -DLADFFKQCGVVKMNKRTGQPMIHIYLDK--ETGKPKGDATVSYEDPPTAKAAVEWFDG 432
+ G + G P + E G+P + PP +G
Sbjct: 175 ISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGK----NG 230
Query: 433 KDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMP-----PPLRG--------GPGGPGG 479
D + K P RG P+ RG+P P ++G G G G
Sbjct: 231 DDGEAGK---------PGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAG 281
Query: 480 PGGPMGRMG--GRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWR 537
P GP G G G G G PRG G RG P G R D G
Sbjct: 282 PAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAG--------- 332
Query: 538 TECNQCKAPKPEGFLPPP-FPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDR 596
P P G PP FP G +G GP G RG G RG PG G G
Sbjct: 333 -------PPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPA 385
Query: 597 G--------GFRGGRG----MDRGGFGGGR----RGGPGGPPGPLMEQMGGRRGGRGGPG 640
G G +G G GF G R GPGGPPGP G G G PG
Sbjct: 386 GNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGP-----KGNSGEPGAPG 440
Query: 641 -KMDKG 645
K D G
Sbjct: 441 SKGDTG 446
Score = 82.0 bits (201), Expect = 2e-15
Identities = 148/526 (28%), Positives = 180/526 (34%), Gaps = 67/526 (12%)
Query: 136 PTRPQDGNKPTETSQ-----PQSSTG--GYNQPSLGYGQSNY-SYPQVPGSYPMQPVTAP 187
P P PT+ P+ TG G P+ G+ P +PG P P P
Sbjct: 93 PVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGP-PGPP--GP 149
Query: 188 PSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSY 247
P P + SY Y +++T G S G G + G PP + PQ +
Sbjct: 150 PGPPGLGGNFAPQLSY---GYDEKST-GGISVPGPMGPSGPRGLPG--PPGAPGPQ--GF 201
Query: 248 SQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGF 307
P + + +S P G G E+G PGE R GP G
Sbjct: 202 QGPPGEPGEPGASGPMGPRGPPGPPGKNGDDG-EAGKPGRPGE-RGPPGPQGARGLPGTA 259
Query: 308 DRGGMSRGGRG--GGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYV 365
GM +G RG G G G AG G +PG P + G +GP P E A
Sbjct: 260 GLPGM-KGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGP 318
Query: 366 QGL--NDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKP--KGDATVSYEDPP 421
G ND T G TG G P G E P
Sbjct: 319 AGARGNDGAT-----------GAAGPPGPTG----------PAGPPGFPGAVGAKGEAGP 357
Query: 422 TAKAAVEWFDG-KDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPG-- 478
E G + G A P N G P +G P + G PG PG
Sbjct: 358 QGPRGSEGPQGVRGEPGPPGPAGAA--GPAGNPGADGQPGAKGANGAPGIAGAPGFPGAR 415
Query: 479 GPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRT 538
GP GP G GG G +G G GS+G+ +G G P P R
Sbjct: 416 GPSGPQG-PGGPPGPKGNSGEPGAPGSKGD-TGAKGEPGPVGVQGPPGPAGEEGKRGARG 473
Query: 539 ECNQCKAPKPEGFLPPP----FPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGG 594
E P P G P FP G G GP G RG G +G PG GR G
Sbjct: 474 EPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPG---EAGRPG 530
Query: 595 DRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPG 640
+ G G +G+ G G G GPPGP + GR G G PG
Sbjct: 531 E-AGLPGAKGL-TGSPGSPGPDGKTGPPGPAGQD--GRPGPPGPPG 572
Score = 77.0 bits (188), Expect = 5e-14
Identities = 158/584 (27%), Positives = 198/584 (33%), Gaps = 106/584 (18%)
Query: 122 PAYPA--YGQQPAATAPT---RPQDGNKPTETSQP--QSSTGGYNQPSLGYGQSNYSYPQ 174
PA PA G+Q A +P P P E +P Q G P + +P
Sbjct: 624 PAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPG 683
Query: 175 VPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQ 234
G V PP ++ P + + G P + G Q + G Q G+
Sbjct: 684 ERG------VQGPPGPAGPRGANGAP-----GNDGAKGDAGAPGAPGSQGAPGLQGMPGE 732
Query: 235 QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQD--HPSSMGVYGQES-GGFSGP-GE 290
+ P G A + + S P G G + G SGP G
Sbjct: 733 RGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGP 792
Query: 291 NRSMSGPDNRGR----GRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDL 346
+ P +RG G GF G G+ G +G G AG +G D GP
Sbjct: 793 TGARGAPGDRGEPGPPGPAGF-AGPPGADGQPGAKGEPGDAGAKG---------DAGPPG 842
Query: 347 DLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKM---NKRTGQPMIHIYLD 403
GP P + A +G S F G V + G P
Sbjct: 843 PAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAG 902
Query: 404 KETGK-PKGDA-------TVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMR 455
KE GK P+G+ V PP A + G D A P +
Sbjct: 903 KEGGKGPRGETGPAGRPGEVGPPGPP-GPAGEKGSPGADGPAG------APGTPGPQGIA 955
Query: 456 G-----GLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG--GRGGDRGGFPPRGPRGSRGN 508
G GLP + G RG PG PG P G G+ G G G+RG P GP G G
Sbjct: 956 GQRGVVGLPGQRGE------RGFPGLPG-PSGEPGKQGPSGASGERGPPGPMGPPGLAGP 1008
Query: 509 PSGGGNVQHRAGDWQCP----NPGCGNQNFAWRTECNQCKAPKPEGF--LPPPFPPPG-- 560
P G + G P +PG R E P G P P P G
Sbjct: 1009 PGESGR-EGAPGAEGSPGRDGSPGAKGD----RGETGPAGPPGAPGAPGAPGPVGPAGKS 1063
Query: 561 GDRGRGGPGGMRGGRGGLMDRG--GPGGMFRGGRG-----GDRG--GFRGGRGM------ 605
GDRG GP G G G + RG GP G RG +G GDRG G RG G+
Sbjct: 1064 GDRGETGPAGPAGPVGPVGARGPAGPQGP-RGDKGETGEQGDRGIKGHRGFSGLQGPPGP 1122
Query: 606 -----DRGGFGG----GRRGGPGGPPGPLMEQMGGRRGGRGGPG 640
++G G G RG PG P + + G G G PG
Sbjct: 1123 PGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPG 1166
Score = 77.0 bits (188), Expect = 5e-14
Identities = 113/455 (24%), Positives = 150/455 (32%), Gaps = 78/455 (17%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQ----APSQYSQQSSSYGQQSSFRQD 270
G P G G+ G PT G + P+ ++ + GQ + +
Sbjct: 770 GPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGA--KG 827
Query: 271 HPSSMGVYGQE-----SGGFSGPGENRSMSGPDNRGR-------GRGGFDR-----GGMS 313
P G G +G PG ++ P +G G GF G
Sbjct: 828 EPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPG 887
Query: 314 RGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVT 373
G G G G AG+ GG G G ++GPP P + + G +
Sbjct: 888 PSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPG 947
Query: 374 LDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKP--KGDATVSYEDPPTAKAAVEWFD 431
Q GVV + + G+ L +G+P +G + S E P
Sbjct: 948 TPGPQGIAGQRGVVGLPGQRGERGFP-GLPGPSGEPGKQGPSGASGERGPPGPMGPPGLA 1006
Query: 432 GKDFQGSKLKVSLARKKPPMNSMRGGLPPR--EGRGMPPPLRGGPGGPG----------- 478
G + + A P + G R G PP G PG PG
Sbjct: 1007 GPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDR 1066
Query: 479 ------GPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQ 532
GP GP+G +G RG P GP+G RG+ G R G++
Sbjct: 1067 GETGPAGPAGPVGPVGARG-------PAGPQGPRGDKGETGEQGDRGIK--------GHR 1111
Query: 533 NFAWRTECNQCKAPKPEGFLPPPFPPPG-GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGG 591
F+ G PP PP G++G G G G RG G PG G
Sbjct: 1112 GFS--------------GLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNG 1157
Query: 592 RGGDRG--GFRGGRGMDRGGFGGGRRGGPGGPPGP 624
G G G RG G D G G GP GPPGP
Sbjct: 1158 LPGPIGPPGPRGRTG-DAGPVGPPGPPGPPGPPGP 1191
Score = 70.5 bits (171), Expect = 5e-12
Identities = 72/197 (36%), Positives = 81/197 (41%), Gaps = 34/197 (17%)
Query: 473 GPGGPGGPGGPMGRMG--GRGGDRG--GFP-PRGPRGSRGNPSGGGNV---------QHR 518
GP G GP GP G G GR G G G P P GP G G P GGN +
Sbjct: 112 GPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKS 171
Query: 519 AGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGL 578
G P P + R AP P+GF PP P G+ G GP G RG G
Sbjct: 172 TGGISVPGPMGPS---GPRGLPGPPGAPGPQGFQGPPGEP--GEPGASGPMGPRGPPGPP 226
Query: 579 MDRGGPGGMFRGGRGGDRG--GFRGGRGM-DRGGFGG--GRRG--------GPGGPPGPL 625
G G + GR G+RG G +G RG+ G G G RG G GP GP
Sbjct: 227 GKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPK 286
Query: 626 MEQMGGRRGGRGGPGKM 642
E G G G PG+M
Sbjct: 287 GEP--GSPGENGAPGQM 301
Score = 44.3 bits (103), Expect = 4e-04
Identities = 77/326 (23%), Positives = 95/326 (29%), Gaps = 51/326 (15%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 274
G P G G + G+ P P + G P ++ S + P
Sbjct: 893 GPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGP-PGPAGEKGSPGADGPAGAPGTPGP 951
Query: 275 MGVYGQ-----------ESG--GFSGPGENRSMSGPDNRGRGRGGFDRGG----MSRGGR 317
G+ GQ E G G GP GP RG G G
Sbjct: 952 QGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGE 1011
Query: 318 GGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDL 377
G G G+ G G PG D G GPP P + G +
Sbjct: 1012 SGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGP 1071
Query: 378 ADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDF-- 435
A G V G P+GD + E F G
Sbjct: 1072 AGPAGPVGPVGARGPAGPQ-----------GPRGDKGETGEQGDRGIKGHRGFSGLQGPP 1120
Query: 436 --------QGSKLKVSLARKKPPMNSMRGGLPPREG-RGMPPPLRGGPGGPGGPGGPMGR 486
QG A + P S G P ++G G+P P+ GP GP G G G
Sbjct: 1121 GPPGSPGEQGPSGASGPAGPRGPPGS--AGAPGKDGLNGLPGPI--GPPGPRGRTGDAGP 1176
Query: 487 MGGRGGDRGGFPPRGPRGSRGNPSGG 512
+G G P GP G G PS G
Sbjct: 1177 VGPPG-------PPGPPGPPGPPSAG 1195
Score = 32.0 bits (71), Expect = 1.9
Identities = 39/153 (25%), Positives = 48/153 (31%), Gaps = 11/153 (7%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFR--QDHP 272
G P G G + G P G+ A Q + + R + H
Sbjct: 1052 GAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHR 1111
Query: 273 SSMGVYGQE----SGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAG 328
G+ G S G GP +GP RG G G + G G G +G G
Sbjct: 1112 GFSGLQGPPGPPGSPGEQGPSGASGPAGP----RGPPG-SAGAPGKDGLNGLPGPIGPPG 1166
Query: 329 ERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNS 361
RG G GP GPP P D S
Sbjct: 1167 PRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFS 1199
Score = 29.6 bits (65), Expect = 9.2
Identities = 35/113 (30%), Positives = 40/113 (35%), Gaps = 19/113 (16%)
Query: 542 QCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRG--------GRGGLMDR----GGPGGMFR 589
+C P+G P G G G G RG GR G+ + G PG
Sbjct: 90 ECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGP 149
Query: 590 GGRGGDRGGF--RGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPG 640
G G G F + G D GG GP GP GP G G G PG
Sbjct: 150 PGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGP-----RGLPGPPGAPG 197
>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
sapiens]
Length = 1818
Score = 93.2 bits (230), Expect = 7e-19
Identities = 141/534 (26%), Positives = 187/534 (35%), Gaps = 54/534 (10%)
Query: 130 QPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPS 189
Q T P + PT P+ ++GG P G+ PQ P +P PP
Sbjct: 893 QRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPP-GERGPQGPQGPVGFPGPK--GPPG 949
Query: 190 YPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQ 249
P P ++ + Q G P G G G +P G
Sbjct: 950 PPGKDGLPGHPGQRGETGF--QGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG---- 1003
Query: 250 APSQYSQQSSSYGQQSSFRQDHPSSMGVYGQES-GGFSG-PGENRSMSGPDNRGRGRGGF 307
P + G++ + + P G+ G++ G G PGE R + G +GG
Sbjct: 1004 -PPGEQGLPGAAGKEGA--KGDPGPQGISGKDGPAGLRGFPGE-RGLPGAQGAPGLKGG- 1058
Query: 308 DRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQG 367
G G G G GSAG G PG P +GP G P E G
Sbjct: 1059 -EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1117
Query: 368 LNDSVTLDDLADFFKQCGVVKMNKRTGQP-MIHIYLDKETGKPKGDATVSYEDPPTAKAA 426
+ V L A G G+P DK P G + P
Sbjct: 1118 VQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQ---GPVGAPG 1174
Query: 427 VEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPR----EGRGMPPPLRG-----GPGGP 477
+ DG+ G + + + +K + PP +G PP +G GP GP
Sbjct: 1175 IAGGDGEP--GPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP 1232
Query: 478 GGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNP----GCGNQN 533
GP GP G G G D P+GP GS G+ G G + G+ P P G G
Sbjct: 1233 PGPPGPRGPQGPNGAD----GPQGPPGSVGSVGGVGE-KGEPGEAGNPGPPGEAGVGGP- 1286
Query: 534 FAWRTECNQCKAPKPEGFLPPPFP--PPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGG 591
+ E + P G PP PPG D +G PG + G G G PG + G
Sbjct: 1287 ---KGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV-GFPGDPGPPGEPGPAGQDG 1342
Query: 592 RGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPG----PLMEQMGGRRGGRGGPGK 641
GGD+G G G G GP GPPG P GR+G +G G+
Sbjct: 1343 VGGDKG--EDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1394
Score = 89.7 bits (221), Expect = 7e-18
Identities = 130/482 (26%), Positives = 162/482 (33%), Gaps = 118/482 (24%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQ----------APSQYSQQSSSYGQQ 264
G+P GQQ + G Q G Q P P + G + P + + G++
Sbjct: 697 GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK 756
Query: 265 SSFRQD-------HPSSMGVYGQ-----------ESGGFSGPGENRSMSGPDNRG----- 301
+ +P GV G E G PG M +RG
Sbjct: 757 GALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQI 816
Query: 302 --RGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPG---GPMDEGPDLDLGPPVDPDE 356
RG G G R G G G G AGE+G PG P +GP G P P
Sbjct: 817 GPRGEDG-PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGA 875
Query: 357 DSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVS 416
+ + A V G + G TG P TGKP T
Sbjct: 876 NGEKGARGVAG---------------KPGPRGQRGPTG-PRGSRGARGPTGKPGPKGTSG 919
Query: 417 YEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK-PPMNSMRGGLPPREGRGMPPPLRG--G 473
+ PP + QG + V K PP + GLP G+ +G G
Sbjct: 920 GDGPPGPPGE------RGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 973
Query: 474 PGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGN 531
P GPGG GP G G G G+RG P GP G +G P G + GD
Sbjct: 974 PPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK-EGAKGD---------- 1022
Query: 532 QNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGG 591
P P G G+ GP G+RG G +RG PG G
Sbjct: 1023 -------------------------PGPQGISGKDGPAGLRGFPG---ERGLPGAQGAPG 1054
Query: 592 RGGDRG-----------GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQ-MGGRRGGRGGP 639
G G G RG G G G R GP GPPGP E+ G +G +G
Sbjct: 1055 LKGGEGPQGPPGPVGSPGERGSAGT-AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPA 1113
Query: 640 GK 641
G+
Sbjct: 1114 GR 1115
Score = 84.7 bits (208), Expect = 2e-16
Identities = 161/569 (28%), Positives = 205/569 (36%), Gaps = 84/569 (14%)
Query: 121 QPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYP 180
+P P P PQ P PQ G P +P G
Sbjct: 698 EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPG---ADGPPGHPGKEGQSG 754
Query: 181 MQPVTAPPS------YP-PTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYG 233
+ PP YP P + S ++ G P G G + G
Sbjct: 755 EKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG 814
Query: 234 QQPPTSYPPQTGSYSQA-PSQYSQQSSSYGQQSSFR----QDHPSSMGVYGQESGGFSG- 287
Q P G +A P+ S G++ +P G G S GF G
Sbjct: 815 QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKG--STGFPGF 872
Query: 288 PGEN-----RSMSG-PDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMD 341
PG N R ++G P RG+ RG SRG RG G G G GG PG P +
Sbjct: 873 PGANGEKGARGVAGKPGPRGQRGPTGPRG--SRGARGP-TGKPGPKGTSGGDGPPGPPGE 929
Query: 342 EGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIY 401
GP GP P +G D L Q G +TG P
Sbjct: 930 RGPQGPQGPVGFPGP---------KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGV 980
Query: 402 LDKE--TGK--PKGDATVSYEDPPTAKAAVEWFDGKD-FQGSKLKVSLARKKPPMNSMRG 456
+ + TG+ P G+ P + + GK+ +G ++ K P +RG
Sbjct: 981 VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG-LRG 1039
Query: 457 -----GLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG--GDRG--GFPPR-GPRGSR 506
GLP +G P L+GG G P GP GP+G G RG G G G P R GP+G
Sbjct: 1040 FPGERGLPGAQGA---PGLKGGEG-PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPP 1095
Query: 507 GNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRG 566
G P+G G Q P G Q P P G P P GD+G
Sbjct: 1096 G-PAGEKGAPGEKGP-QGPAGRDGVQG--------PVGLPGPAG--PAGSPGEDGDKGEI 1143
Query: 567 GPGGMRGGRGGLMDRG--GPGGM-----FRGGRGGD-RGGFRGGRGMDRGGFGGGRRGGP 618
G G +G +G + G GP G+ G GGD G RG +GM G RG P
Sbjct: 1144 GEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFP 1203
Query: 619 GGPPGPLMEQMGGRRGGRGGPGKMDKGEH 647
GPPGP+ G +G G PG +KGE+
Sbjct: 1204 -GPPGPI-----GLQGLPGPPG--EKGEN 1224
Score = 80.5 bits (197), Expect = 5e-15
Identities = 113/373 (30%), Positives = 140/373 (37%), Gaps = 105/373 (28%)
Query: 310 GGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLN 369
G M GR G GG GS+G +G + G P +GP GPP
Sbjct: 544 GPMGLTGRPGPVGGPGSSGAKG---ESGDPGPQGPRGVQGPPGP---------------- 584
Query: 370 DSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEW 429
TG+P + G+P D P AK
Sbjct: 585 -----------------------TGKP-------GKRGRPGADGGRGMPGEPGAKGD-RG 613
Query: 430 FDG-------KDFQGSKLKVSLARKKPPMNSMRG--------GLPPREG-RGMPPPLRGG 473
FDG K +G + P + MRG GLP G RG+ P RG
Sbjct: 614 FDGLPGLPGDKGHRGERGPQG-PPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGP-RGT 671
Query: 474 PGGPGGPG--------GPMGRMGGRG-----GDRGGFPPRGPRGSRG--NPSGGGNVQHR 518
PG PG PG GP G MG +G G +G P+G G +G P G Q +
Sbjct: 672 PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 731
Query: 519 AG-------DWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGM 571
G D +PG Q+ E P P+G P +P P G +G G G+
Sbjct: 732 PGLAGLPGADGPPGHPGKEGQS----GEKGALGPPGPQG--PIGYPGPRGVKGADGVRGL 785
Query: 572 RGGRGGLMDRGGPGGMFRGGRG--GDRG--GFRGGRGMDRGGFGGGRRGGPGGPPGPLME 627
+G +G + G PG F+G G GDRG G G RG D G G R GP G PGP
Sbjct: 786 KGSKGEKGEDGFPG--FKGDMGLKGDRGEVGQIGPRGED-GPEGPKGRAGPTGDPGP--S 840
Query: 628 QMGGRRGGRGGPG 640
G +G G PG
Sbjct: 841 GQAGEKGKLGVPG 853
Score = 78.6 bits (192), Expect = 2e-14
Identities = 135/496 (27%), Positives = 178/496 (35%), Gaps = 97/496 (19%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 274
G P S G + G G + P TG P + + + G+ P
Sbjct: 556 GGPGSSGAKGESGDPGPQGPRGVQGPPGPTGK----PGKRGRPGADGGRGM------PGE 605
Query: 275 MGVYGQESGGFSG----PGEN-----RSMSGP-----DNRGRGRGGFDRGGMSRGGRGGG 320
G G GF G PG+ R GP D+ RG G + G G G
Sbjct: 606 PGAKGDR--GFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDG-EIGPRGLPGEAGP 662
Query: 321 RGGMGSAGERGGFNKPG-----GPMDEGPDLDLGPPVDPDEDSDNSAIYVQGL---NDSV 372
RG +G G G +PG GP GP ++GP +P QGL +
Sbjct: 663 RGLLGPRGTPGAPGQPGMAGVDGP--PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPI 720
Query: 373 TLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGK------PKGDATVSYEDPPTAKAA 426
+ G+ + G P H + ++G+ P + Y P K A
Sbjct: 721 GPPGEKGPQGKPGLAGLPGADGPPG-HPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGA 779
Query: 427 VEWFDG-KDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMG 485
DG + +GSK + + + +G + + RG + GP G GP GP G
Sbjct: 780 ----DGVRGLKGSKGE----KGEDGFPGFKGDMGLKGDRGEVGQI--GPRGEDGPEGPKG 829
Query: 486 RMG--------GRGGDRG--------GFPPR-GPRGSRGNPSGGGNVQHRAGDWQCPNPG 528
R G G+ G++G G+P R GP+GS G P G + PG
Sbjct: 830 RAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPG 889
Query: 529 CGNQN-----FAWRTECNQCKAPKPEGFLPPPFPP-PGGDRGRGGPGGMRGGRGGLMDRG 582
Q R P P+G PP P G+RG GP G G G G
Sbjct: 890 PRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPG 949
Query: 583 GPGGMFRGGRGGDRG--GFRGGRG-MDRGGFGG-----------GRRGGPGGPPGPLMEQ 628
PG G G RG GF+G G GG G G RG P GPPGP EQ
Sbjct: 950 PPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHP-GPPGPPGEQ 1008
Query: 629 ----MGGRRGGRGGPG 640
G+ G +G PG
Sbjct: 1009 GLPGAAGKEGAKGDPG 1024
Score = 78.6 bits (192), Expect = 2e-14
Identities = 120/404 (29%), Positives = 151/404 (37%), Gaps = 84/404 (20%)
Query: 272 PSSMGVYGQESGGFSGPGENRSMSGPDNRG-----RGRGGFDRG-GM-----SRGGRG-- 318
P S G G+ G GP R + GP RGR G D G GM ++G RG
Sbjct: 558 PGSSGAKGES--GDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFD 615
Query: 319 ---GGRGGMGSAGERGGFNKPGGPMDE---GPDLDLGPPVDPDEDSDNSAIYVQGLNDSV 372
G G G GERG PG P D+ G D ++GP P E + +G +
Sbjct: 616 GLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGA- 674
Query: 373 TLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDG 432
GQP + +D G PKG+ E P +
Sbjct: 675 --------------------PGQPGM-AGVDGPPG-PKGNMGPQGEPGPPGQ-------- 704
Query: 433 KDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGG 492
QG+ L + P+ G P +G P L G PG G PG P G+ G
Sbjct: 705 ---QGNPGPQGLPGPQGPI-----GPPGEKGPQGKPGLAGLPGADGPPGHP--GKEGQSG 754
Query: 493 DRGGFPPRGPRGSRGNP-----SGGGNVQHRAGD----WQCPNPGC-GNQNFAW-RTECN 541
++G P GP+G G P G V+ G + PG G+ R E
Sbjct: 755 EKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG 814
Query: 542 QCKAPKPEGFLPPPFPPPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-- 597
Q +G P P G G G GP G G +G L G PG R G G G
Sbjct: 815 QIGPRGEDG----PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 870
Query: 598 GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 641
GF G G ++G G + GP G GP + G RG RG GK
Sbjct: 871 GFPGANG-EKGARGVAGKPGPRGQRGPTGPR--GSRGARGPTGK 911
Score = 77.0 bits (188), Expect = 5e-14
Identities = 131/464 (28%), Positives = 171/464 (36%), Gaps = 111/464 (23%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 274
G+ + G++ G G Q P P G P+ + G+ P
Sbjct: 1099 GEKGAPGEKGPQGPAGRDGVQGPVGLPGPAG-----PAGSPGEDGDKGEIGE-----PGQ 1148
Query: 275 MGVYGQ--ESG-----GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSA 327
G G E+G G GP ++G D RG +G + G G RG G
Sbjct: 1149 KGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRG--QQGMFGQKGDEGARGFPGPP 1206
Query: 328 GERGGFNKPGGPMDEGPDLDLGPPVDPDE------DSDNSAIYVQGLNDSVTLDDLADFF 381
G G PG P ++G + D+GP P N A QG SV
Sbjct: 1207 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV--------- 1257
Query: 382 KQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLK 441
G V G+P E G P P +A V G+ +G K +
Sbjct: 1258 ---GSVGGVGEKGEP-------GEAGNPG----------PPGEAGVGGPKGE--RGEKGE 1295
Query: 442 VSLARKKPPMNSMRGGLPPREG-RGMPPPLRGGPGGPGGPG--GPMGRMGGRGGDRG--- 495
P + G P +G +G P P+ G PG PG PG GP G+ G GGD+G
Sbjct: 1296 AGPPGAAGPPGAK--GPPGDDGPKGNPGPV-GFPGDPGPPGEPGPAGQ-DGVGGDKGEDG 1351
Query: 496 --GFP----------PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQC 543
G P P GP G RG P G + R G+ + +
Sbjct: 1352 DPGQPGPPGPSGEAGPPGPPGKRG-PPGAAGAEGRQGE---------------KGAKGEA 1395
Query: 544 KAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRG 601
A P G P P G G+ GP G+RG G + ++G PG + G G G G G
Sbjct: 1396 GAEGPPGKTGPVGPQ--GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPG 1453
Query: 602 GRGMDRGGFGGGRRGGPG-----GPPGPLMEQMGGRRGGRGGPG 640
+G D G G +G PG GPPG EQ G +G RG PG
Sbjct: 1454 LKG-DPG--SKGEKGHPGLIGLIGPPG---EQ--GEKGDRGLPG 1489
Score = 70.5 bits (171), Expect = 5e-12
Identities = 84/264 (31%), Positives = 98/264 (37%), Gaps = 44/264 (16%)
Query: 417 YEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGG 476
YED PT+ E+ G + + S+ + G P GM L GP G
Sbjct: 401 YEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGM---LVEGPPG 457
Query: 477 PGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGG---------NVQHRAGDWQCP 525
P GP G MG G +G G G RGP G G P G + R G
Sbjct: 458 PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 517
Query: 526 NPGCGNQNFAWRTECNQCKA-----PKPEGFLPPPFPPPG-------GDRGRGGPGGMRG 573
P Q + Q + P P G P P G G+ G GP G RG
Sbjct: 518 GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 577
Query: 574 GRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGMDRGGFGG-----GRRG--GPGGP 621
+G G PG R G G RG G +G RG D G G G RG GP GP
Sbjct: 578 VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFD--GLPGLPGDKGHRGERGPQGP 635
Query: 622 PGPL----MEQMGGRRGGRGGPGK 641
PGP M G G RG PG+
Sbjct: 636 PGPPGDDGMRGEDGEIGPRGLPGE 659
Score = 65.5 bits (158), Expect = 2e-10
Identities = 105/408 (25%), Positives = 131/408 (32%), Gaps = 81/408 (19%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQSSFRQDHPS 273
G+P GQQ +GQ+ G + P G P ++ G P
Sbjct: 1180 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1239
Query: 274 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGF 333
G PG S+ G +G + G G GG +G G GE G
Sbjct: 1240 GPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPP 1299
Query: 334 NKPGGPMDEGPDLDLGP---------PVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQC 384
G P +GP D GP P DP + G+ D
Sbjct: 1300 GAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDG-------- 1351
Query: 385 GVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSK-LKVS 443
GQP G P PP + + QG K K
Sbjct: 1352 -------DPGQP----------GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1394
Query: 444 LARKKPPMNSMR------GGLPPREG-RGMPPPL--RGGPGGPG--GPGGPMGRMG--GR 490
+ PP + G P EG RG+P P+ +G PG G GP GPMG G G
Sbjct: 1395 AGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGL 1454
Query: 491 GGDRGGFPPRGPRGSRGNPS-----GGGNVQHRAGDWQCP----NPGCGNQNFAWRTECN 541
GD G +G +G+P G Q GD P +PG
Sbjct: 1455 KGDPGS------KGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDG-------- 1500
Query: 542 QCKAPKPEGFLPPPFPP----PGGDRGRGGPGGMRGGRGGLMDRGGPG 585
P P G L PP PP P G +G G G G +G D G PG
Sbjct: 1501 --GIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKG---DSGLPG 1543
Score = 61.6 bits (148), Expect = 2e-09
Identities = 68/188 (36%), Positives = 76/188 (40%), Gaps = 23/188 (12%)
Query: 464 RGMPPP--LRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRG---PRGSRGNPSGGGNVQHR 518
RG P P L G PG GGPG + G GD G PRG P G G P G
Sbjct: 540 RGPPGPMGLTGRPGPVGGPGSSGAK--GESGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD 597
Query: 519 AGDWQCPNPGC-GNQNFAWRTECNQCKAPKPE-GFLPPPFPPPGGDRGRGGPGGMRGGRG 576
G PG G++ F K + E G PP PP G GMRG G
Sbjct: 598 GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP--------GDDGMRGEDG 649
Query: 577 GLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRG--GPGGPPGPLMEQMGGR 632
+ RG PG G G RG G G GM G +G GP G PGP +Q G
Sbjct: 650 EIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQ--GN 707
Query: 633 RGGRGGPG 640
G +G PG
Sbjct: 708 PGPQGLPG 715
Score = 47.4 bits (111), Expect = 4e-05
Identities = 87/379 (22%), Positives = 123/379 (32%), Gaps = 69/379 (18%)
Query: 172 YPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSS 231
+P PG +Q + PP ++ G P G + G +
Sbjct: 1202 FPGPPGPIGLQGLPGPPG--------------EKGENGDVGPMGPPGPPGPRGPQGPNGA 1247
Query: 232 YGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESG--GFSGPG 289
G Q P G + ++ + G P E+G G +GP
Sbjct: 1248 DGPQGPPGSVGSVGGVGEKGEP--GEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP 1305
Query: 290 ENRSMSGPDNRGRGRG--GFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLD 347
+ G D G GF G G G G G G++G PG P GP +
Sbjct: 1306 GAKGPPGDDGPKGNPGPVGFP-GDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGE 1364
Query: 348 LGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETG 407
GPP P + A +G + G +TG + G
Sbjct: 1365 AGPPGPPGKRGPPGAAGAEGRQGEKGAKG------EAGAEGPPGKTGP----VGPQGPAG 1414
Query: 408 KP--------------KGDATVSYEDPPTAKAAVEWFDG-KDFQGSKLKVSLARKKPPMN 452
KP +G + +D P G K GSK + + P +
Sbjct: 1415 KPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGE----KGHPGLI 1470
Query: 453 SMRGGLPPRE-----GRGMP-----PPLRG-----GPGGPGGPGGPMGRMGGRG--GDRG 495
+ G PP E RG+P P +G GP GP GP GP G G +G G++G
Sbjct: 1471 GLIG--PPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKG 1528
Query: 496 GFPPRGPRGSRGNPSGGGN 514
P G +G G P G+
Sbjct: 1529 STGPAGQKGDSGLPGPPGS 1547
Score = 37.4 bits (85), Expect = 0.044
Identities = 76/329 (23%), Positives = 97/329 (29%), Gaps = 34/329 (10%)
Query: 188 PSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSY 247
P PP S S ++ + G P G G++ G+ P G+
Sbjct: 1250 PQGPPGSVGSVGGVG-EKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAK 1308
Query: 248 S----QAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRG 303
P G + P+ G + G PG+ G
Sbjct: 1309 GPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPP 1368
Query: 304 RGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAI 363
RG G G +G G+ GE G PG GP G P +
Sbjct: 1369 GPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV 1428
Query: 364 YVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTA 423
QGL + D G+ + G E G P + PP
Sbjct: 1429 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSK-------GEKGHP---GLIGLIGPPGE 1478
Query: 424 KAAVEWFDGKDFQGSKLKVSL-ARKKPPMNSMRGGLP-PREGRGMP-PPLRGGPGGPGGP 480
QG K L + P GG+P P G P PP GP GP G
Sbjct: 1479 ------------QGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN 1526
Query: 481 GGPMGRMGGRGGDRGGFPPRGPRGSRGNP 509
G G G +G G P GP GS G P
Sbjct: 1527 KGSTGPAGQKGD--SGLP--GPPGSPGPP 1551
Score = 33.9 bits (76), Expect = 0.49
Identities = 52/260 (20%), Positives = 81/260 (31%), Gaps = 36/260 (13%)
Query: 151 PQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYP----PTSYSSTQPTSYDQS 206
P G Q +G + P PG PP P P + + ++
Sbjct: 1331 PPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKG 1390
Query: 207 SYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQ-- 264
+ + G P G G G + P G Q + Q G
Sbjct: 1391 AKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGE--QGLPGAAGQDGPPGPMGP 1448
Query: 265 -----------SSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR--GRGRGGFDRGG 311
S + HP +G+ G G G +R + G +G GG
Sbjct: 1449 PGLPGLKGDPGSKGEKGHPGLIGLIGPP--GEQGEKGDRGLPGTQGSPGAKGDGGIPGPA 1506
Query: 312 MSRGGRG-----------GGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN 360
G G G +G G AG++G PG P GP ++ P+ P S
Sbjct: 1507 GPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPL-PILSSKK 1565
Query: 361 SAIYVQGLNDSVTLDDLADF 380
+ + +G+ D++ D+
Sbjct: 1566 TRRHTEGMQADAD-DNILDY 1584
>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
sapiens]
Length = 1767
Score = 93.2 bits (230), Expect = 7e-19
Identities = 141/534 (26%), Positives = 187/534 (35%), Gaps = 54/534 (10%)
Query: 130 QPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPS 189
Q T P + PT P+ ++GG P G+ PQ P +P PP
Sbjct: 842 QRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPP-GERGPQGPQGPVGFPGPK--GPPG 898
Query: 190 YPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQ 249
P P ++ + Q G P G G G +P G
Sbjct: 899 PPGKDGLPGHPGQRGETGF--QGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG---- 952
Query: 250 APSQYSQQSSSYGQQSSFRQDHPSSMGVYGQES-GGFSG-PGENRSMSGPDNRGRGRGGF 307
P + G++ + + P G+ G++ G G PGE R + G +GG
Sbjct: 953 -PPGEQGLPGAAGKEGA--KGDPGPQGISGKDGPAGLRGFPGE-RGLPGAQGAPGLKGG- 1007
Query: 308 DRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQG 367
G G G G GSAG G PG P +GP G P E G
Sbjct: 1008 -EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1066
Query: 368 LNDSVTLDDLADFFKQCGVVKMNKRTGQP-MIHIYLDKETGKPKGDATVSYEDPPTAKAA 426
+ V L A G G+P DK P G + P
Sbjct: 1067 VQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQ---GPVGAPG 1123
Query: 427 VEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPR----EGRGMPPPLRG-----GPGGP 477
+ DG+ G + + + +K + PP +G PP +G GP GP
Sbjct: 1124 IAGGDGEP--GPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP 1181
Query: 478 GGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNP----GCGNQN 533
GP GP G G G D P+GP GS G+ G G + G+ P P G G
Sbjct: 1182 PGPPGPRGPQGPNGAD----GPQGPPGSVGSVGGVGE-KGEPGEAGNPGPPGEAGVGGP- 1235
Query: 534 FAWRTECNQCKAPKPEGFLPPPFP--PPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGG 591
+ E + P G PP PPG D +G PG + G G G PG + G
Sbjct: 1236 ---KGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV-GFPGDPGPPGEPGPAGQDG 1291
Query: 592 RGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPG----PLMEQMGGRRGGRGGPGK 641
GGD+G G G G GP GPPG P GR+G +G G+
Sbjct: 1292 VGGDKG--EDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1343
Score = 89.7 bits (221), Expect = 7e-18
Identities = 130/482 (26%), Positives = 162/482 (33%), Gaps = 118/482 (24%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQ----------APSQYSQQSSSYGQQ 264
G+P GQQ + G Q G Q P P + G + P + + G++
Sbjct: 646 GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK 705
Query: 265 SSFRQD-------HPSSMGVYGQ-----------ESGGFSGPGENRSMSGPDNRG----- 301
+ +P GV G E G PG M +RG
Sbjct: 706 GALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQI 765
Query: 302 --RGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPG---GPMDEGPDLDLGPPVDPDE 356
RG G G R G G G G AGE+G PG P +GP G P P
Sbjct: 766 GPRGEDG-PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGA 824
Query: 357 DSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVS 416
+ + A V G + G TG P TGKP T
Sbjct: 825 NGEKGARGVAG---------------KPGPRGQRGPTG-PRGSRGARGPTGKPGPKGTSG 868
Query: 417 YEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK-PPMNSMRGGLPPREGRGMPPPLRG--G 473
+ PP + QG + V K PP + GLP G+ +G G
Sbjct: 869 GDGPPGPPGE------RGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 922
Query: 474 PGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGN 531
P GPGG GP G G G G+RG P GP G +G P G + GD
Sbjct: 923 PPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK-EGAKGD---------- 971
Query: 532 QNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGG 591
P P G G+ GP G+RG G +RG PG G
Sbjct: 972 -------------------------PGPQGISGKDGPAGLRGFPG---ERGLPGAQGAPG 1003
Query: 592 RGGDRG-----------GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQ-MGGRRGGRGGP 639
G G G RG G G G R GP GPPGP E+ G +G +G
Sbjct: 1004 LKGGEGPQGPPGPVGSPGERGSAGT-AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPA 1062
Query: 640 GK 641
G+
Sbjct: 1063 GR 1064
Score = 84.7 bits (208), Expect = 2e-16
Identities = 161/569 (28%), Positives = 205/569 (36%), Gaps = 84/569 (14%)
Query: 121 QPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYP 180
+P P P PQ P PQ G P +P G
Sbjct: 647 EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPG---ADGPPGHPGKEGQSG 703
Query: 181 MQPVTAPPS------YP-PTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYG 233
+ PP YP P + S ++ G P G G + G
Sbjct: 704 EKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG 763
Query: 234 QQPPTSYPPQTGSYSQA-PSQYSQQSSSYGQQSSFR----QDHPSSMGVYGQESGGFSG- 287
Q P G +A P+ S G++ +P G G S GF G
Sbjct: 764 QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKG--STGFPGF 821
Query: 288 PGEN-----RSMSG-PDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMD 341
PG N R ++G P RG+ RG SRG RG G G G GG PG P +
Sbjct: 822 PGANGEKGARGVAGKPGPRGQRGPTGPRG--SRGARGP-TGKPGPKGTSGGDGPPGPPGE 878
Query: 342 EGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIY 401
GP GP P +G D L Q G +TG P
Sbjct: 879 RGPQGPQGPVGFPGP---------KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGV 929
Query: 402 LDKE--TGK--PKGDATVSYEDPPTAKAAVEWFDGKD-FQGSKLKVSLARKKPPMNSMRG 456
+ + TG+ P G+ P + + GK+ +G ++ K P +RG
Sbjct: 930 VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG-LRG 988
Query: 457 -----GLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG--GDRG--GFPPR-GPRGSR 506
GLP +G P L+GG G P GP GP+G G RG G G G P R GP+G
Sbjct: 989 FPGERGLPGAQGA---PGLKGGEG-PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPP 1044
Query: 507 GNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRG 566
G P+G G Q P G Q P P G P P GD+G
Sbjct: 1045 G-PAGEKGAPGEKGP-QGPAGRDGVQG--------PVGLPGPAG--PAGSPGEDGDKGEI 1092
Query: 567 GPGGMRGGRGGLMDRG--GPGGM-----FRGGRGGD-RGGFRGGRGMDRGGFGGGRRGGP 618
G G +G +G + G GP G+ G GGD G RG +GM G RG P
Sbjct: 1093 GEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFP 1152
Query: 619 GGPPGPLMEQMGGRRGGRGGPGKMDKGEH 647
GPPGP+ G +G G PG +KGE+
Sbjct: 1153 -GPPGPI-----GLQGLPGPPG--EKGEN 1173
Score = 80.5 bits (197), Expect = 5e-15
Identities = 113/373 (30%), Positives = 140/373 (37%), Gaps = 105/373 (28%)
Query: 310 GGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLN 369
G M GR G GG GS+G +G + G P +GP GPP
Sbjct: 493 GPMGLTGRPGPVGGPGSSGAKG---ESGDPGPQGPRGVQGPPGP---------------- 533
Query: 370 DSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEW 429
TG+P + G+P D P AK
Sbjct: 534 -----------------------TGKP-------GKRGRPGADGGRGMPGEPGAKGD-RG 562
Query: 430 FDG-------KDFQGSKLKVSLARKKPPMNSMRG--------GLPPREG-RGMPPPLRGG 473
FDG K +G + P + MRG GLP G RG+ P RG
Sbjct: 563 FDGLPGLPGDKGHRGERGPQG-PPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGP-RGT 620
Query: 474 PGGPGGPG--------GPMGRMGGRG-----GDRGGFPPRGPRGSRG--NPSGGGNVQHR 518
PG PG PG GP G MG +G G +G P+G G +G P G Q +
Sbjct: 621 PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 680
Query: 519 AG-------DWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGM 571
G D +PG Q+ E P P+G P +P P G +G G G+
Sbjct: 681 PGLAGLPGADGPPGHPGKEGQS----GEKGALGPPGPQG--PIGYPGPRGVKGADGVRGL 734
Query: 572 RGGRGGLMDRGGPGGMFRGGRG--GDRG--GFRGGRGMDRGGFGGGRRGGPGGPPGPLME 627
+G +G + G PG F+G G GDRG G G RG D G G R GP G PGP
Sbjct: 735 KGSKGEKGEDGFPG--FKGDMGLKGDRGEVGQIGPRGED-GPEGPKGRAGPTGDPGP--S 789
Query: 628 QMGGRRGGRGGPG 640
G +G G PG
Sbjct: 790 GQAGEKGKLGVPG 802
Score = 78.6 bits (192), Expect = 2e-14
Identities = 135/496 (27%), Positives = 178/496 (35%), Gaps = 97/496 (19%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 274
G P S G + G G + P TG P + + + G+ P
Sbjct: 505 GGPGSSGAKGESGDPGPQGPRGVQGPPGPTGK----PGKRGRPGADGGRGM------PGE 554
Query: 275 MGVYGQESGGFSG----PGEN-----RSMSGP-----DNRGRGRGGFDRGGMSRGGRGGG 320
G G GF G PG+ R GP D+ RG G + G G G
Sbjct: 555 PGAKGDR--GFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDG-EIGPRGLPGEAGP 611
Query: 321 RGGMGSAGERGGFNKPG-----GPMDEGPDLDLGPPVDPDEDSDNSAIYVQGL---NDSV 372
RG +G G G +PG GP GP ++GP +P QGL +
Sbjct: 612 RGLLGPRGTPGAPGQPGMAGVDGP--PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPI 669
Query: 373 TLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGK------PKGDATVSYEDPPTAKAA 426
+ G+ + G P H + ++G+ P + Y P K A
Sbjct: 670 GPPGEKGPQGKPGLAGLPGADGPPG-HPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGA 728
Query: 427 VEWFDG-KDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMG 485
DG + +GSK + + + +G + + RG + GP G GP GP G
Sbjct: 729 ----DGVRGLKGSKGE----KGEDGFPGFKGDMGLKGDRGEVGQI--GPRGEDGPEGPKG 778
Query: 486 RMG--------GRGGDRG--------GFPPR-GPRGSRGNPSGGGNVQHRAGDWQCPNPG 528
R G G+ G++G G+P R GP+GS G P G + PG
Sbjct: 779 RAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPG 838
Query: 529 CGNQN-----FAWRTECNQCKAPKPEGFLPPPFPP-PGGDRGRGGPGGMRGGRGGLMDRG 582
Q R P P+G PP P G+RG GP G G G G
Sbjct: 839 PRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPG 898
Query: 583 GPGGMFRGGRGGDRG--GFRGGRG-MDRGGFGG-----------GRRGGPGGPPGPLMEQ 628
PG G G RG GF+G G GG G G RG P GPPGP EQ
Sbjct: 899 PPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHP-GPPGPPGEQ 957
Query: 629 ----MGGRRGGRGGPG 640
G+ G +G PG
Sbjct: 958 GLPGAAGKEGAKGDPG 973
Score = 78.6 bits (192), Expect = 2e-14
Identities = 120/404 (29%), Positives = 151/404 (37%), Gaps = 84/404 (20%)
Query: 272 PSSMGVYGQESGGFSGPGENRSMSGPDNRG-----RGRGGFDRG-GM-----SRGGRG-- 318
P S G G+ G GP R + GP RGR G D G GM ++G RG
Sbjct: 507 PGSSGAKGES--GDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFD 564
Query: 319 ---GGRGGMGSAGERGGFNKPGGPMDE---GPDLDLGPPVDPDEDSDNSAIYVQGLNDSV 372
G G G GERG PG P D+ G D ++GP P E + +G +
Sbjct: 565 GLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGA- 623
Query: 373 TLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDG 432
GQP + +D G PKG+ E P +
Sbjct: 624 --------------------PGQPGM-AGVDGPPG-PKGNMGPQGEPGPPGQ-------- 653
Query: 433 KDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGG 492
QG+ L + P+ G P +G P L G PG G PG P G+ G
Sbjct: 654 ---QGNPGPQGLPGPQGPI-----GPPGEKGPQGKPGLAGLPGADGPPGHP--GKEGQSG 703
Query: 493 DRGGFPPRGPRGSRGNP-----SGGGNVQHRAGD----WQCPNPGC-GNQNFAW-RTECN 541
++G P GP+G G P G V+ G + PG G+ R E
Sbjct: 704 EKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG 763
Query: 542 QCKAPKPEGFLPPPFPPPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-- 597
Q +G P P G G G GP G G +G L G PG R G G G
Sbjct: 764 QIGPRGEDG----PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 819
Query: 598 GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 641
GF G G ++G G + GP G GP + G RG RG GK
Sbjct: 820 GFPGANG-EKGARGVAGKPGPRGQRGPTGPR--GSRGARGPTGK 860
Score = 77.0 bits (188), Expect = 5e-14
Identities = 131/464 (28%), Positives = 171/464 (36%), Gaps = 111/464 (23%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 274
G+ + G++ G G Q P P G P+ + G+ P
Sbjct: 1048 GEKGAPGEKGPQGPAGRDGVQGPVGLPGPAG-----PAGSPGEDGDKGEIGE-----PGQ 1097
Query: 275 MGVYGQ--ESG-----GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSA 327
G G E+G G GP ++G D RG +G + G G RG G
Sbjct: 1098 KGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRG--QQGMFGQKGDEGARGFPGPP 1155
Query: 328 GERGGFNKPGGPMDEGPDLDLGPPVDPDE------DSDNSAIYVQGLNDSVTLDDLADFF 381
G G PG P ++G + D+GP P N A QG SV
Sbjct: 1156 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV--------- 1206
Query: 382 KQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLK 441
G V G+P E G P P +A V G+ +G K +
Sbjct: 1207 ---GSVGGVGEKGEP-------GEAGNPG----------PPGEAGVGGPKGE--RGEKGE 1244
Query: 442 VSLARKKPPMNSMRGGLPPREG-RGMPPPLRGGPGGPGGPG--GPMGRMGGRGGDRG--- 495
P + G P +G +G P P+ G PG PG PG GP G+ G GGD+G
Sbjct: 1245 AGPPGAAGPPGAK--GPPGDDGPKGNPGPV-GFPGDPGPPGEPGPAGQ-DGVGGDKGEDG 1300
Query: 496 --GFP----------PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQC 543
G P P GP G RG P G + R G+ + +
Sbjct: 1301 DPGQPGPPGPSGEAGPPGPPGKRG-PPGAAGAEGRQGE---------------KGAKGEA 1344
Query: 544 KAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRG 601
A P G P P G G+ GP G+RG G + ++G PG + G G G G G
Sbjct: 1345 GAEGPPGKTGPVGPQ--GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPG 1402
Query: 602 GRGMDRGGFGGGRRGGPG-----GPPGPLMEQMGGRRGGRGGPG 640
+G D G G +G PG GPPG EQ G +G RG PG
Sbjct: 1403 LKG-DPG--SKGEKGHPGLIGLIGPPG---EQ--GEKGDRGLPG 1438
Score = 70.5 bits (171), Expect = 5e-12
Identities = 84/264 (31%), Positives = 98/264 (37%), Gaps = 44/264 (16%)
Query: 417 YEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGG 476
YED PT+ E+ G + + S+ + G P GM L GP G
Sbjct: 350 YEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGM---LVEGPPG 406
Query: 477 PGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGG---------NVQHRAGDWQCP 525
P GP G MG G +G G G RGP G G P G + R G
Sbjct: 407 PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 466
Query: 526 NPGCGNQNFAWRTECNQCKA-----PKPEGFLPPPFPPPG-------GDRGRGGPGGMRG 573
P Q + Q + P P G P P G G+ G GP G RG
Sbjct: 467 GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 526
Query: 574 GRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGMDRGGFGG-----GRRG--GPGGP 621
+G G PG R G G RG G +G RG D G G G RG GP GP
Sbjct: 527 VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFD--GLPGLPGDKGHRGERGPQGP 584
Query: 622 PGPL----MEQMGGRRGGRGGPGK 641
PGP M G G RG PG+
Sbjct: 585 PGPPGDDGMRGEDGEIGPRGLPGE 608
Score = 65.5 bits (158), Expect = 2e-10
Identities = 105/408 (25%), Positives = 131/408 (32%), Gaps = 81/408 (19%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQSSFRQDHPS 273
G+P GQQ +GQ+ G + P G P ++ G P
Sbjct: 1129 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1188
Query: 274 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGF 333
G PG S+ G +G + G G GG +G G GE G
Sbjct: 1189 GPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPP 1248
Query: 334 NKPGGPMDEGPDLDLGP---------PVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQC 384
G P +GP D GP P DP + G+ D
Sbjct: 1249 GAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDG-------- 1300
Query: 385 GVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSK-LKVS 443
GQP G P PP + + QG K K
Sbjct: 1301 -------DPGQP----------GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1343
Query: 444 LARKKPPMNSMR------GGLPPREG-RGMPPPL--RGGPGGPG--GPGGPMGRMG--GR 490
+ PP + G P EG RG+P P+ +G PG G GP GPMG G G
Sbjct: 1344 AGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGL 1403
Query: 491 GGDRGGFPPRGPRGSRGNPS-----GGGNVQHRAGDWQCP----NPGCGNQNFAWRTECN 541
GD G +G +G+P G Q GD P +PG
Sbjct: 1404 KGDPGS------KGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDG-------- 1449
Query: 542 QCKAPKPEGFLPPPFPP----PGGDRGRGGPGGMRGGRGGLMDRGGPG 585
P P G L PP PP P G +G G G G +G D G PG
Sbjct: 1450 --GIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKG---DSGLPG 1492
Score = 61.6 bits (148), Expect = 2e-09
Identities = 68/188 (36%), Positives = 76/188 (40%), Gaps = 23/188 (12%)
Query: 464 RGMPPP--LRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRG---PRGSRGNPSGGGNVQHR 518
RG P P L G PG GGPG + G GD G PRG P G G P G
Sbjct: 489 RGPPGPMGLTGRPGPVGGPGSSGAK--GESGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD 546
Query: 519 AGDWQCPNPGC-GNQNFAWRTECNQCKAPKPE-GFLPPPFPPPGGDRGRGGPGGMRGGRG 576
G PG G++ F K + E G PP PP G GMRG G
Sbjct: 547 GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP--------GDDGMRGEDG 598
Query: 577 GLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRG--GPGGPPGPLMEQMGGR 632
+ RG PG G G RG G G GM G +G GP G PGP +Q G
Sbjct: 599 EIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQ--GN 656
Query: 633 RGGRGGPG 640
G +G PG
Sbjct: 657 PGPQGLPG 664
Score = 47.4 bits (111), Expect = 4e-05
Identities = 87/379 (22%), Positives = 123/379 (32%), Gaps = 69/379 (18%)
Query: 172 YPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSS 231
+P PG +Q + PP ++ G P G + G +
Sbjct: 1151 FPGPPGPIGLQGLPGPPG--------------EKGENGDVGPMGPPGPPGPRGPQGPNGA 1196
Query: 232 YGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESG--GFSGPG 289
G Q P G + ++ + G P E+G G +GP
Sbjct: 1197 DGPQGPPGSVGSVGGVGEKGEP--GEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP 1254
Query: 290 ENRSMSGPDNRGRGRG--GFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLD 347
+ G D G GF G G G G G G++G PG P GP +
Sbjct: 1255 GAKGPPGDDGPKGNPGPVGFP-GDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGE 1313
Query: 348 LGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETG 407
GPP P + A +G + G +TG + G
Sbjct: 1314 AGPPGPPGKRGPPGAAGAEGRQGEKGAKG------EAGAEGPPGKTGP----VGPQGPAG 1363
Query: 408 KP--------------KGDATVSYEDPPTAKAAVEWFDG-KDFQGSKLKVSLARKKPPMN 452
KP +G + +D P G K GSK + + P +
Sbjct: 1364 KPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGE----KGHPGLI 1419
Query: 453 SMRGGLPPRE-----GRGMP-----PPLRG-----GPGGPGGPGGPMGRMGGRG--GDRG 495
+ G PP E RG+P P +G GP GP GP GP G G +G G++G
Sbjct: 1420 GLIG--PPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKG 1477
Query: 496 GFPPRGPRGSRGNPSGGGN 514
P G +G G P G+
Sbjct: 1478 STGPAGQKGDSGLPGPPGS 1496
Score = 37.4 bits (85), Expect = 0.044
Identities = 76/329 (23%), Positives = 97/329 (29%), Gaps = 34/329 (10%)
Query: 188 PSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSY 247
P PP S S ++ + G P G G++ G+ P G+
Sbjct: 1199 PQGPPGSVGSVGGVG-EKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAK 1257
Query: 248 S----QAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRG 303
P G + P+ G + G PG+ G
Sbjct: 1258 GPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPP 1317
Query: 304 RGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAI 363
RG G G +G G+ GE G PG GP G P +
Sbjct: 1318 GPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV 1377
Query: 364 YVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTA 423
QGL + D G+ + G E G P + PP
Sbjct: 1378 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSK-------GEKGHP---GLIGLIGPPGE 1427
Query: 424 KAAVEWFDGKDFQGSKLKVSL-ARKKPPMNSMRGGLP-PREGRGMP-PPLRGGPGGPGGP 480
QG K L + P GG+P P G P PP GP GP G
Sbjct: 1428 ------------QGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN 1475
Query: 481 GGPMGRMGGRGGDRGGFPPRGPRGSRGNP 509
G G G +G G P GP GS G P
Sbjct: 1476 KGSTGPAGQKGD--SGLP--GPPGSPGPP 1500
Score = 33.9 bits (76), Expect = 0.49
Identities = 52/260 (20%), Positives = 81/260 (31%), Gaps = 36/260 (13%)
Query: 151 PQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYP----PTSYSSTQPTSYDQS 206
P G Q +G + P PG PP P P + + ++
Sbjct: 1280 PPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKG 1339
Query: 207 SYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQ-- 264
+ + G P G G G + P G Q + Q G
Sbjct: 1340 AKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGE--QGLPGAAGQDGPPGPMGP 1397
Query: 265 -----------SSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR--GRGRGGFDRGG 311
S + HP +G+ G G G +R + G +G GG
Sbjct: 1398 PGLPGLKGDPGSKGEKGHPGLIGLIGPP--GEQGEKGDRGLPGTQGSPGAKGDGGIPGPA 1455
Query: 312 MSRGGRG-----------GGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN 360
G G G +G G AG++G PG P GP ++ P+ P S
Sbjct: 1456 GPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPL-PILSSKK 1514
Query: 361 SAIYVQGLNDSVTLDDLADF 380
+ + +G+ D++ D+
Sbjct: 1515 TRRHTEGMQADAD-DNILDY 1533
>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
sapiens]
Length = 1806
Score = 93.2 bits (230), Expect = 7e-19
Identities = 141/534 (26%), Positives = 187/534 (35%), Gaps = 54/534 (10%)
Query: 130 QPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPS 189
Q T P + PT P+ ++GG P G+ PQ P +P PP
Sbjct: 881 QRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPP-GERGPQGPQGPVGFPGPK--GPPG 937
Query: 190 YPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQ 249
P P ++ + Q G P G G G +P G
Sbjct: 938 PPGKDGLPGHPGQRGETGF--QGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG---- 991
Query: 250 APSQYSQQSSSYGQQSSFRQDHPSSMGVYGQES-GGFSG-PGENRSMSGPDNRGRGRGGF 307
P + G++ + + P G+ G++ G G PGE R + G +GG
Sbjct: 992 -PPGEQGLPGAAGKEGA--KGDPGPQGISGKDGPAGLRGFPGE-RGLPGAQGAPGLKGG- 1046
Query: 308 DRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQG 367
G G G G GSAG G PG P +GP G P E G
Sbjct: 1047 -EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG 1105
Query: 368 LNDSVTLDDLADFFKQCGVVKMNKRTGQP-MIHIYLDKETGKPKGDATVSYEDPPTAKAA 426
+ V L A G G+P DK P G + P
Sbjct: 1106 VQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQ---GPVGAPG 1162
Query: 427 VEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPR----EGRGMPPPLRG-----GPGGP 477
+ DG+ G + + + +K + PP +G PP +G GP GP
Sbjct: 1163 IAGGDGEP--GPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGP 1220
Query: 478 GGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNP----GCGNQN 533
GP GP G G G D P+GP GS G+ G G + G+ P P G G
Sbjct: 1221 PGPPGPRGPQGPNGAD----GPQGPPGSVGSVGGVGE-KGEPGEAGNPGPPGEAGVGGP- 1274
Query: 534 FAWRTECNQCKAPKPEGFLPPPFP--PPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGG 591
+ E + P G PP PPG D +G PG + G G G PG + G
Sbjct: 1275 ---KGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPV-GFPGDPGPPGEPGPAGQDG 1330
Query: 592 RGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPG----PLMEQMGGRRGGRGGPGK 641
GGD+G G G G GP GPPG P GR+G +G G+
Sbjct: 1331 VGGDKG--EDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1382
Score = 89.7 bits (221), Expect = 7e-18
Identities = 130/482 (26%), Positives = 162/482 (33%), Gaps = 118/482 (24%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQ----------APSQYSQQSSSYGQQ 264
G+P GQQ + G Q G Q P P + G + P + + G++
Sbjct: 685 GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK 744
Query: 265 SSFRQD-------HPSSMGVYGQ-----------ESGGFSGPGENRSMSGPDNRG----- 301
+ +P GV G E G PG M +RG
Sbjct: 745 GALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQI 804
Query: 302 --RGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPG---GPMDEGPDLDLGPPVDPDE 356
RG G G R G G G G AGE+G PG P +GP G P P
Sbjct: 805 GPRGEDG-PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGA 863
Query: 357 DSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVS 416
+ + A V G + G TG P TGKP T
Sbjct: 864 NGEKGARGVAG---------------KPGPRGQRGPTG-PRGSRGARGPTGKPGPKGTSG 907
Query: 417 YEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK-PPMNSMRGGLPPREGRGMPPPLRG--G 473
+ PP + QG + V K PP + GLP G+ +G G
Sbjct: 908 GDGPPGPPGE------RGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 961
Query: 474 PGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGN 531
P GPGG GP G G G G+RG P GP G +G P G + GD
Sbjct: 962 PPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK-EGAKGD---------- 1010
Query: 532 QNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGG 591
P P G G+ GP G+RG G +RG PG G
Sbjct: 1011 -------------------------PGPQGISGKDGPAGLRGFPG---ERGLPGAQGAPG 1042
Query: 592 RGGDRG-----------GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQ-MGGRRGGRGGP 639
G G G RG G G G R GP GPPGP E+ G +G +G
Sbjct: 1043 LKGGEGPQGPPGPVGSPGERGSAGT-AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPA 1101
Query: 640 GK 641
G+
Sbjct: 1102 GR 1103
Score = 84.7 bits (208), Expect = 2e-16
Identities = 161/569 (28%), Positives = 205/569 (36%), Gaps = 84/569 (14%)
Query: 121 QPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYP 180
+P P P PQ P PQ G P +P G
Sbjct: 686 EPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPG---ADGPPGHPGKEGQSG 742
Query: 181 MQPVTAPPS------YP-PTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYG 233
+ PP YP P + S ++ G P G G + G
Sbjct: 743 EKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG 802
Query: 234 QQPPTSYPPQTGSYSQA-PSQYSQQSSSYGQQSSFR----QDHPSSMGVYGQESGGFSG- 287
Q P G +A P+ S G++ +P G G S GF G
Sbjct: 803 QIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKG--STGFPGF 860
Query: 288 PGEN-----RSMSG-PDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMD 341
PG N R ++G P RG+ RG SRG RG G G G GG PG P +
Sbjct: 861 PGANGEKGARGVAGKPGPRGQRGPTGPRG--SRGARGP-TGKPGPKGTSGGDGPPGPPGE 917
Query: 342 EGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIY 401
GP GP P +G D L Q G +TG P
Sbjct: 918 RGPQGPQGPVGFPGP---------KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGV 968
Query: 402 LDKE--TGK--PKGDATVSYEDPPTAKAAVEWFDGKD-FQGSKLKVSLARKKPPMNSMRG 456
+ + TG+ P G+ P + + GK+ +G ++ K P +RG
Sbjct: 969 VGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAG-LRG 1027
Query: 457 -----GLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG--GDRG--GFPPR-GPRGSR 506
GLP +G P L+GG G P GP GP+G G RG G G G P R GP+G
Sbjct: 1028 FPGERGLPGAQGA---PGLKGGEG-PQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPP 1083
Query: 507 GNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRG 566
G P+G G Q P G Q P P G P P GD+G
Sbjct: 1084 G-PAGEKGAPGEKGP-QGPAGRDGVQG--------PVGLPGPAG--PAGSPGEDGDKGEI 1131
Query: 567 GPGGMRGGRGGLMDRG--GPGGM-----FRGGRGGD-RGGFRGGRGMDRGGFGGGRRGGP 618
G G +G +G + G GP G+ G GGD G RG +GM G RG P
Sbjct: 1132 GEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFP 1191
Query: 619 GGPPGPLMEQMGGRRGGRGGPGKMDKGEH 647
GPPGP+ G +G G PG +KGE+
Sbjct: 1192 -GPPGPI-----GLQGLPGPPG--EKGEN 1212
Score = 80.5 bits (197), Expect = 5e-15
Identities = 113/373 (30%), Positives = 140/373 (37%), Gaps = 105/373 (28%)
Query: 310 GGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLN 369
G M GR G GG GS+G +G + G P +GP GPP
Sbjct: 532 GPMGLTGRPGPVGGPGSSGAKG---ESGDPGPQGPRGVQGPPGP---------------- 572
Query: 370 DSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEW 429
TG+P + G+P D P AK
Sbjct: 573 -----------------------TGKP-------GKRGRPGADGGRGMPGEPGAKGD-RG 601
Query: 430 FDG-------KDFQGSKLKVSLARKKPPMNSMRG--------GLPPREG-RGMPPPLRGG 473
FDG K +G + P + MRG GLP G RG+ P RG
Sbjct: 602 FDGLPGLPGDKGHRGERGPQG-PPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGP-RGT 659
Query: 474 PGGPGGPG--------GPMGRMGGRG-----GDRGGFPPRGPRGSRG--NPSGGGNVQHR 518
PG PG PG GP G MG +G G +G P+G G +G P G Q +
Sbjct: 660 PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 719
Query: 519 AG-------DWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGM 571
G D +PG Q+ E P P+G P +P P G +G G G+
Sbjct: 720 PGLAGLPGADGPPGHPGKEGQS----GEKGALGPPGPQG--PIGYPGPRGVKGADGVRGL 773
Query: 572 RGGRGGLMDRGGPGGMFRGGRG--GDRG--GFRGGRGMDRGGFGGGRRGGPGGPPGPLME 627
+G +G + G PG F+G G GDRG G G RG D G G R GP G PGP
Sbjct: 774 KGSKGEKGEDGFPG--FKGDMGLKGDRGEVGQIGPRGED-GPEGPKGRAGPTGDPGP--S 828
Query: 628 QMGGRRGGRGGPG 640
G +G G PG
Sbjct: 829 GQAGEKGKLGVPG 841
Score = 78.6 bits (192), Expect = 2e-14
Identities = 135/496 (27%), Positives = 178/496 (35%), Gaps = 97/496 (19%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 274
G P S G + G G + P TG P + + + G+ P
Sbjct: 544 GGPGSSGAKGESGDPGPQGPRGVQGPPGPTGK----PGKRGRPGADGGRGM------PGE 593
Query: 275 MGVYGQESGGFSG----PGEN-----RSMSGP-----DNRGRGRGGFDRGGMSRGGRGGG 320
G G GF G PG+ R GP D+ RG G + G G G
Sbjct: 594 PGAKGDR--GFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDG-EIGPRGLPGEAGP 650
Query: 321 RGGMGSAGERGGFNKPG-----GPMDEGPDLDLGPPVDPDEDSDNSAIYVQGL---NDSV 372
RG +G G G +PG GP GP ++GP +P QGL +
Sbjct: 651 RGLLGPRGTPGAPGQPGMAGVDGP--PGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPI 708
Query: 373 TLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGK------PKGDATVSYEDPPTAKAA 426
+ G+ + G P H + ++G+ P + Y P K A
Sbjct: 709 GPPGEKGPQGKPGLAGLPGADGPPG-HPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGA 767
Query: 427 VEWFDG-KDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMG 485
DG + +GSK + + + +G + + RG + GP G GP GP G
Sbjct: 768 ----DGVRGLKGSKGE----KGEDGFPGFKGDMGLKGDRGEVGQI--GPRGEDGPEGPKG 817
Query: 486 RMG--------GRGGDRG--------GFPPR-GPRGSRGNPSGGGNVQHRAGDWQCPNPG 528
R G G+ G++G G+P R GP+GS G P G + PG
Sbjct: 818 RAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPG 877
Query: 529 CGNQN-----FAWRTECNQCKAPKPEGFLPPPFPP-PGGDRGRGGPGGMRGGRGGLMDRG 582
Q R P P+G PP P G+RG GP G G G G
Sbjct: 878 PRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPG 937
Query: 583 GPGGMFRGGRGGDRG--GFRGGRG-MDRGGFGG-----------GRRGGPGGPPGPLMEQ 628
PG G G RG GF+G G GG G G RG P GPPGP EQ
Sbjct: 938 PPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHP-GPPGPPGEQ 996
Query: 629 ----MGGRRGGRGGPG 640
G+ G +G PG
Sbjct: 997 GLPGAAGKEGAKGDPG 1012
Score = 78.6 bits (192), Expect = 2e-14
Identities = 120/404 (29%), Positives = 151/404 (37%), Gaps = 84/404 (20%)
Query: 272 PSSMGVYGQESGGFSGPGENRSMSGPDNRG-----RGRGGFDRG-GM-----SRGGRG-- 318
P S G G+ G GP R + GP RGR G D G GM ++G RG
Sbjct: 546 PGSSGAKGES--GDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFD 603
Query: 319 ---GGRGGMGSAGERGGFNKPGGPMDE---GPDLDLGPPVDPDEDSDNSAIYVQGLNDSV 372
G G G GERG PG P D+ G D ++GP P E + +G +
Sbjct: 604 GLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGA- 662
Query: 373 TLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDG 432
GQP + +D G PKG+ E P +
Sbjct: 663 --------------------PGQPGM-AGVDGPPG-PKGNMGPQGEPGPPGQ-------- 692
Query: 433 KDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGG 492
QG+ L + P+ G P +G P L G PG G PG P G+ G
Sbjct: 693 ---QGNPGPQGLPGPQGPI-----GPPGEKGPQGKPGLAGLPGADGPPGHP--GKEGQSG 742
Query: 493 DRGGFPPRGPRGSRGNP-----SGGGNVQHRAGD----WQCPNPGC-GNQNFAW-RTECN 541
++G P GP+G G P G V+ G + PG G+ R E
Sbjct: 743 EKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG 802
Query: 542 QCKAPKPEGFLPPPFPPPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-- 597
Q +G P P G G G GP G G +G L G PG R G G G
Sbjct: 803 QIGPRGEDG----PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 858
Query: 598 GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 641
GF G G ++G G + GP G GP + G RG RG GK
Sbjct: 859 GFPGANG-EKGARGVAGKPGPRGQRGPTGPR--GSRGARGPTGK 899
Score = 77.0 bits (188), Expect = 5e-14
Identities = 131/464 (28%), Positives = 171/464 (36%), Gaps = 111/464 (23%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 274
G+ + G++ G G Q P P G P+ + G+ P
Sbjct: 1087 GEKGAPGEKGPQGPAGRDGVQGPVGLPGPAG-----PAGSPGEDGDKGEIGE-----PGQ 1136
Query: 275 MGVYGQ--ESG-----GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSA 327
G G E+G G GP ++G D RG +G + G G RG G
Sbjct: 1137 KGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRG--QQGMFGQKGDEGARGFPGPP 1194
Query: 328 GERGGFNKPGGPMDEGPDLDLGPPVDPDE------DSDNSAIYVQGLNDSVTLDDLADFF 381
G G PG P ++G + D+GP P N A QG SV
Sbjct: 1195 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV--------- 1245
Query: 382 KQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLK 441
G V G+P E G P P +A V G+ +G K +
Sbjct: 1246 ---GSVGGVGEKGEP-------GEAGNPG----------PPGEAGVGGPKGE--RGEKGE 1283
Query: 442 VSLARKKPPMNSMRGGLPPREG-RGMPPPLRGGPGGPGGPG--GPMGRMGGRGGDRG--- 495
P + G P +G +G P P+ G PG PG PG GP G+ G GGD+G
Sbjct: 1284 AGPPGAAGPPGAK--GPPGDDGPKGNPGPV-GFPGDPGPPGEPGPAGQ-DGVGGDKGEDG 1339
Query: 496 --GFP----------PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQC 543
G P P GP G RG P G + R G+ + +
Sbjct: 1340 DPGQPGPPGPSGEAGPPGPPGKRG-PPGAAGAEGRQGE---------------KGAKGEA 1383
Query: 544 KAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRG 601
A P G P P G G+ GP G+RG G + ++G PG + G G G G G
Sbjct: 1384 GAEGPPGKTGPVGPQ--GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPG 1441
Query: 602 GRGMDRGGFGGGRRGGPG-----GPPGPLMEQMGGRRGGRGGPG 640
+G D G G +G PG GPPG EQ G +G RG PG
Sbjct: 1442 LKG-DPG--SKGEKGHPGLIGLIGPPG---EQ--GEKGDRGLPG 1477
Score = 70.5 bits (171), Expect = 5e-12
Identities = 84/264 (31%), Positives = 98/264 (37%), Gaps = 44/264 (16%)
Query: 417 YEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGG 476
YED PT+ E+ G + + S+ + G P GM L GP G
Sbjct: 389 YEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGM---LVEGPPG 445
Query: 477 PGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGG---------NVQHRAGDWQCP 525
P GP G MG G +G G G RGP G G P G + R G
Sbjct: 446 PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 505
Query: 526 NPGCGNQNFAWRTECNQCKA-----PKPEGFLPPPFPPPG-------GDRGRGGPGGMRG 573
P Q + Q + P P G P P G G+ G GP G RG
Sbjct: 506 GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 565
Query: 574 GRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGMDRGGFGG-----GRRG--GPGGP 621
+G G PG R G G RG G +G RG D G G G RG GP GP
Sbjct: 566 VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFD--GLPGLPGDKGHRGERGPQGP 623
Query: 622 PGPL----MEQMGGRRGGRGGPGK 641
PGP M G G RG PG+
Sbjct: 624 PGPPGDDGMRGEDGEIGPRGLPGE 647
Score = 65.5 bits (158), Expect = 2e-10
Identities = 105/408 (25%), Positives = 131/408 (32%), Gaps = 81/408 (19%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQSSFRQDHPS 273
G+P GQQ +GQ+ G + P G P ++ G P
Sbjct: 1168 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1227
Query: 274 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGF 333
G PG S+ G +G + G G GG +G G GE G
Sbjct: 1228 GPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPP 1287
Query: 334 NKPGGPMDEGPDLDLGP---------PVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQC 384
G P +GP D GP P DP + G+ D
Sbjct: 1288 GAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDG-------- 1339
Query: 385 GVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSK-LKVS 443
GQP G P PP + + QG K K
Sbjct: 1340 -------DPGQP----------GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1382
Query: 444 LARKKPPMNSMR------GGLPPREG-RGMPPPL--RGGPGGPG--GPGGPMGRMG--GR 490
+ PP + G P EG RG+P P+ +G PG G GP GPMG G G
Sbjct: 1383 AGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGL 1442
Query: 491 GGDRGGFPPRGPRGSRGNPS-----GGGNVQHRAGDWQCP----NPGCGNQNFAWRTECN 541
GD G +G +G+P G Q GD P +PG
Sbjct: 1443 KGDPGS------KGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDG-------- 1488
Query: 542 QCKAPKPEGFLPPPFPP----PGGDRGRGGPGGMRGGRGGLMDRGGPG 585
P P G L PP PP P G +G G G G +G D G PG
Sbjct: 1489 --GIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKG---DSGLPG 1531
Score = 61.6 bits (148), Expect = 2e-09
Identities = 68/188 (36%), Positives = 76/188 (40%), Gaps = 23/188 (12%)
Query: 464 RGMPPP--LRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRG---PRGSRGNPSGGGNVQHR 518
RG P P L G PG GGPG + G GD G PRG P G G P G
Sbjct: 528 RGPPGPMGLTGRPGPVGGPGSSGAK--GESGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD 585
Query: 519 AGDWQCPNPGC-GNQNFAWRTECNQCKAPKPE-GFLPPPFPPPGGDRGRGGPGGMRGGRG 576
G PG G++ F K + E G PP PP G GMRG G
Sbjct: 586 GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP--------GDDGMRGEDG 637
Query: 577 GLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRG--GPGGPPGPLMEQMGGR 632
+ RG PG G G RG G G GM G +G GP G PGP +Q G
Sbjct: 638 EIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQ--GN 695
Query: 633 RGGRGGPG 640
G +G PG
Sbjct: 696 PGPQGLPG 703
Score = 47.4 bits (111), Expect = 4e-05
Identities = 87/379 (22%), Positives = 123/379 (32%), Gaps = 69/379 (18%)
Query: 172 YPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSS 231
+P PG +Q + PP ++ G P G + G +
Sbjct: 1190 FPGPPGPIGLQGLPGPPG--------------EKGENGDVGPMGPPGPPGPRGPQGPNGA 1235
Query: 232 YGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESG--GFSGPG 289
G Q P G + ++ + G P E+G G +GP
Sbjct: 1236 DGPQGPPGSVGSVGGVGEKGEP--GEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP 1293
Query: 290 ENRSMSGPDNRGRGRG--GFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLD 347
+ G D G GF G G G G G G++G PG P GP +
Sbjct: 1294 GAKGPPGDDGPKGNPGPVGFP-GDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGE 1352
Query: 348 LGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETG 407
GPP P + A +G + G +TG + G
Sbjct: 1353 AGPPGPPGKRGPPGAAGAEGRQGEKGAKG------EAGAEGPPGKTGP----VGPQGPAG 1402
Query: 408 KP--------------KGDATVSYEDPPTAKAAVEWFDG-KDFQGSKLKVSLARKKPPMN 452
KP +G + +D P G K GSK + + P +
Sbjct: 1403 KPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSKGE----KGHPGLI 1458
Query: 453 SMRGGLPPRE-----GRGMP-----PPLRG-----GPGGPGGPGGPMGRMGGRG--GDRG 495
+ G PP E RG+P P +G GP GP GP GP G G +G G++G
Sbjct: 1459 GLIG--PPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKG 1516
Query: 496 GFPPRGPRGSRGNPSGGGN 514
P G +G G P G+
Sbjct: 1517 STGPAGQKGDSGLPGPPGS 1535
Score = 37.4 bits (85), Expect = 0.044
Identities = 76/329 (23%), Positives = 97/329 (29%), Gaps = 34/329 (10%)
Query: 188 PSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSY 247
P PP S S ++ + G P G G++ G+ P G+
Sbjct: 1238 PQGPPGSVGSVGGVG-EKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAK 1296
Query: 248 S----QAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRG 303
P G + P+ G + G PG+ G
Sbjct: 1297 GPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPP 1356
Query: 304 RGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAI 363
RG G G +G G+ GE G PG GP G P +
Sbjct: 1357 GPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV 1416
Query: 364 YVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTA 423
QGL + D G+ + G E G P + PP
Sbjct: 1417 GEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSK-------GEKGHP---GLIGLIGPPGE 1466
Query: 424 KAAVEWFDGKDFQGSKLKVSL-ARKKPPMNSMRGGLP-PREGRGMP-PPLRGGPGGPGGP 480
QG K L + P GG+P P G P PP GP GP G
Sbjct: 1467 ------------QGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGN 1514
Query: 481 GGPMGRMGGRGGDRGGFPPRGPRGSRGNP 509
G G G +G G P GP GS G P
Sbjct: 1515 KGSTGPAGQKGD--SGLP--GPPGSPGPP 1539
Score = 33.9 bits (76), Expect = 0.49
Identities = 52/260 (20%), Positives = 81/260 (31%), Gaps = 36/260 (13%)
Query: 151 PQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYP----PTSYSSTQPTSYDQS 206
P G Q +G + P PG PP P P + + ++
Sbjct: 1319 PPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKG 1378
Query: 207 SYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQ-- 264
+ + G P G G G + P G Q + Q G
Sbjct: 1379 AKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGE--QGLPGAAGQDGPPGPMGP 1436
Query: 265 -----------SSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR--GRGRGGFDRGG 311
S + HP +G+ G G G +R + G +G GG
Sbjct: 1437 PGLPGLKGDPGSKGEKGHPGLIGLIGPP--GEQGEKGDRGLPGTQGSPGAKGDGGIPGPA 1494
Query: 312 MSRGGRG-----------GGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN 360
G G G +G G AG++G PG P GP ++ P+ P S
Sbjct: 1495 GPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPL-PILSSKK 1553
Query: 361 SAIYVQGLNDSVTLDDLADF 380
+ + +G+ D++ D+
Sbjct: 1554 TRRHTEGMQADAD-DNILDY 1572
>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
Length = 1860
Score = 92.8 bits (229), Expect = 9e-19
Identities = 171/636 (26%), Positives = 219/636 (34%), Gaps = 109/636 (17%)
Query: 73 PPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGTQPAYPAYGQQ-P 131
P G T T P A P GT T A T A ++ G++ + A + P
Sbjct: 493 PTPGSTRSTRPPATMVPPTS-GTSTPRTAPAVPTPGSAPTGSKKPIGSEASKKAGPKSSP 551
Query: 132 AATAPTRPQDGNKPTETS---------QPQSSTGGYNQPSLGYGQ----------SNYSY 172
P RP + S QPQ S L Q S YS
Sbjct: 552 RKPVPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSPRPTSSGYSI 611
Query: 173 PQVPGSYPMQPVTAPPSYP-------PTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSS 225
+ GS P + PP P + YG P G +
Sbjct: 612 FHLAGSTPFPLLMGPPGPKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPPGA 671
Query: 226 YGQQSSYGQQPPTSYPPQTG-------SYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVY 278
GQ+ G P ++ G S + P G HP G
Sbjct: 672 KGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAG-----HPGEQGQP 726
Query: 279 GQE-SGGFSGPGENRSMSGP--DNRGRG-RGGFDRGGM-----SRGGRG-----GGRGGM 324
G E S G G + + GP D +G RG G+ S G RG G RG M
Sbjct: 727 GPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKM 786
Query: 325 GSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQC 384
G G G F + G P +G +LG P P V GL + + +
Sbjct: 787 GMPGFPGVFGERGPPGLDGNPGELGLPGPPG---------VPGLIGDLGVLGPIGYPGPK 837
Query: 385 GVVKMNKRTGQPMIHIYLDK-ETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKV- 442
G+ + G+P + DK E G P ++ ++ + + G KV
Sbjct: 838 GMKGLMGSVGEPGLKG--DKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVG 895
Query: 443 ---SLARKKPP-MNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFP 498
S+ PP G + P G P ++G PG G PG P G++G G D G
Sbjct: 896 DKGSIGFPGPPGPEGFPGDIGPPGDNG-PEGMKGKPGARGLPG-PRGQLGPEG-DEGPMG 952
Query: 499 PRGPRGSRGNPSGGG--------NVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEG 550
P G G G P G V+ GD P P G Q F G
Sbjct: 953 PPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGP-VGEQGFM--------------G 997
Query: 551 FL----PPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRG 604
F+ P GDRG GP G+ G +G + G PGGM G G +G G RG G
Sbjct: 998 FIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPG 1057
Query: 605 MDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPG 640
M RG G R GP GP GP EQ G RG +G PG
Sbjct: 1058 M-RGAKG---RRGPRGPDGPAGEQ--GSRGLKGPPG 1087
Score = 85.1 bits (209), Expect = 2e-16
Identities = 144/546 (26%), Positives = 182/546 (33%), Gaps = 136/546 (24%)
Query: 131 PAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSY 190
P P PQ P P+ G +P L G++ P P +
Sbjct: 1128 PGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLP-GEAGMKGDLGPLGTPGEQGLIGQRG 1186
Query: 191 PPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQA 250
P + P D + G P G+ GQ+ G+ P P TG +
Sbjct: 1187 EPGLEGDSGPMGPD----GLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGV--RG 1240
Query: 251 PSQYSQQSSSYGQQSSFR----QDHPSSMGVYGQESG-GFSGPGENRSMSGPDNR-GR-- 302
P S + G+ + Q MGV G G GP +R GP GR
Sbjct: 1241 PEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMG 1300
Query: 303 -----GRGGFD--RGGMSRGGRGGGRGGMGSAGERG-GFNKPGGPMDEGPDLDLGPPVDP 354
G G+D +G + G G +G G GE G PG P D GP D G +P
Sbjct: 1301 AQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEP 1360
Query: 355 DEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDAT 414
+ VQGL G+P + G+P
Sbjct: 1361 GDPGYPGQEGVQGLR------------------------GKP-------GQQGQPGHPGP 1389
Query: 415 VSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREG----RGMPPPL 470
+ P +K A +G K K A G P R G +G+P P
Sbjct: 1390 RGWPGPKGSKGA---------EGPKGKQGKA-----------GAPGRRGVQGLQGLPGPR 1429
Query: 471 ----RGGPGGPGGPGGPMGRMG-----GRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGD 521
R G G GP G GR G G GD G P GP G RGNP G
Sbjct: 1430 GVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAG-------- 1481
Query: 522 WQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRG--GRGGLM 579
P +G PP F G G+ GP G RG GR GL
Sbjct: 1482 -----------------------LPGAQG--PPGFKGESGLPGQLGPPGKRGTEGRTGLP 1516
Query: 580 -DRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGG 638
++G PG + G G+ GF G G+ GP GPPG + G +G RG
Sbjct: 1517 GNQGEPGSKGQPGDSGEM-GFPGMAGL----------FGPKGPPGDI--GFKGIQGPRGP 1563
Query: 639 PGKMDK 644
PG M K
Sbjct: 1564 PGLMGK 1569
Score = 80.5 bits (197), Expect = 5e-15
Identities = 147/546 (26%), Positives = 177/546 (32%), Gaps = 121/546 (22%)
Query: 173 PQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSY 232
P + G + + PP P S P G P G G Q
Sbjct: 1005 PGIVGEKGDRGMMGPPGVPGPKGSMGHP--------------GMPGGMGTPGEPGPQGPP 1050
Query: 233 GQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQS----SFRQDHPSSMGVYGQE----SG 283
G + P G + P + + S G + R P GV G+ S
Sbjct: 1051 GSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSR 1110
Query: 284 GFSG-PGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDE 342
GF G PG SGP +G G + G G G G MG G G +PG P +
Sbjct: 1111 GFPGIPGP----SGPPGT-KGLPG-EPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEA 1164
Query: 343 GPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYL 402
G DLGP P E QGL L G + G P
Sbjct: 1165 GMKGDLGPLGTPGE---------QGLIGQRGEPGLEGDSGPMGPDGLKGDRGDP----GP 1211
Query: 403 DKETGKPKGDATVSYEDPPTAKAAVEWFDGKD----FQGSKLKVSLARKK---------- 448
D E G+ KG + ED P V G + QG K + K
Sbjct: 1212 DGEHGE-KGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMG 1270
Query: 449 ----------PPMNSMRG-----GLPPREGRGMPPPLRGGPG-----GPGGPGGPMGRMG 488
P RG G P R G P L G G GP GP GP G G
Sbjct: 1271 VPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKG 1330
Query: 489 GRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKP 548
+G D P GP G RG P G + GD PG Q + +P
Sbjct: 1331 EQGEDGKAEGPPGPPGDRG-PVGDRGDRGEPGD-----PGYPGQEGVQGLRGKPGQQGQP 1384
Query: 549 EGFLPPPFPPPGGDRGRGGPGGMRG-----------------------GRGGLMDRGGPG 585
P +P P G +G GP G +G GR GL GP
Sbjct: 1385 GHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPD 1444
Query: 586 GM-FRGGRGGDRGGFRGGRGMDRGGFG-GGRRGGPG--------GPPGPLMEQMGGRRGG 635
G+ R G+ G +G G D G G G+RG PG GPPG + G G
Sbjct: 1445 GLPGRDGQAGQQG--EQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPG--FKGESGLPGQ 1500
Query: 636 RGGPGK 641
G PGK
Sbjct: 1501 LGPPGK 1506
Score = 73.9 bits (180), Expect = 4e-13
Identities = 122/440 (27%), Positives = 153/440 (34%), Gaps = 97/440 (22%)
Query: 272 PSSMGVYGQESG-GFSGPGENRSMSGP-----DNRGRGRGGFDRGGMSRGGRG--GGRGG 323
P +G G + GF GP G DN G G G RG G RG
Sbjct: 888 PGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKG------KPGARGLPGPRGQ 941
Query: 324 MGSAGERGGFNKPGGPMDEG----------PDLDLGPPVDPDEDSDNSAIYVQGLNDSVT 373
+G G+ G PG P EG P LD G +P + + QG +
Sbjct: 942 LGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLD-GVKGEPGDPGRPGPVGEQGFMGFIG 1000
Query: 374 LDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSY---EDPPTAKAAVEWF 430
L + G M G P + G P G T + PP ++
Sbjct: 1001 LVGEPGIVGEKGDRGMMGPPGVPGPKGSMG-HPGMPGGMGTPGEPGPQGPPGSRGPPGMR 1059
Query: 431 DGKDFQGSK-------LKVSLARKKPPMNSMRGGLPPREG----------RGMP------ 467
K +G + + S K PP R G P ++G RG P
Sbjct: 1060 GAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPS 1119
Query: 468 --PPLRG-----GPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAG 520
P +G GP GP GP GP G MG P+GP G+ G P G +
Sbjct: 1120 GPPGTKGLPGEPGPQGPQGPIGPPGEMG----------PKGPPGAVGEPGLPGEAGMKGD 1169
Query: 521 DWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPG--GDRGRGGPGGMRGGRG-- 576
P G Q Q P EG P P G GDRG GP G G +G
Sbjct: 1170 LGPLGTP--GEQGL-----IGQRGEPGLEGD-SGPMGPDGLKGDRGDPGPDGEHGEKGQE 1221
Query: 577 GLMDRGGP----------GGMFRGGRGGDRG--GFRGGRGM--DRGGFGGGRRGGPGGPP 622
GLM GP G + G+ G++G G +G +G G G GP G P
Sbjct: 1222 GLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTP 1281
Query: 623 GPLMEQMGGRRGGRGGPGKM 642
GP + G G G PG+M
Sbjct: 1282 GP--KGSRGSLGPTGAPGRM 1299
Score = 65.9 bits (159), Expect = 1e-10
Identities = 128/458 (27%), Positives = 150/458 (32%), Gaps = 107/458 (23%)
Query: 272 PSSMGVYGQESG-GFSG-PGENRSMSGPDNRGR----GRGGF-----------------D 308
P + G+ GQ GF G PG + P + GR G GF D
Sbjct: 954 PGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGD 1013
Query: 309 RGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGL 368
RG M G G +G MG G GG PG P GP GPP A +G
Sbjct: 1014 RGMMGPPGVPGPKGSMGHPGMPGGMGTPGEP---GPQ---GPPGSRGPPGMRGA---KGR 1064
Query: 369 NDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVE 428
D A G+ G+P G+P G V+ E
Sbjct: 1065 RGPRGPDGPAGEQGSRGLKGPPGPQGRP----------GRP-GQQGVAGERGHLGSRGFP 1113
Query: 429 WFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPRE-GRGMPPPLRGGPGGPGGPG-----G 482
G G L + P PP E G PP G PG PG G G
Sbjct: 1114 GIPGPS--GPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLG 1171
Query: 483 PMGRMGGRG-----------GDRGGFPPRGPRGSRGNPSGGGNVQHRA-----GDWQCPN 526
P+G G +G GD G P G +G RG+P G + G+ P
Sbjct: 1172 PLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPG 1231
Query: 527 PG-----------CGNQNFAWRTECNQCKAPK--------PEGFLPPPFPPPGGDRGRGG 567
P G Q RT K + P PP P P G RG G
Sbjct: 1232 PPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLG 1291
Query: 568 PGGMRG-----GRGGLMDRGG----------PGGMFRGGRGGDRGGFRGGRGM--DRGGF 610
P G G G GL G PG G G+ G G G DRG
Sbjct: 1292 PTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPV 1351
Query: 611 GG-GRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEH 647
G G RG PG P P E G +G RG PG+ + H
Sbjct: 1352 GDRGDRGEPGDPGYPGQE---GVQGLRGKPGQQGQPGH 1386
Score = 47.8 bits (112), Expect = 3e-05
Identities = 87/323 (26%), Positives = 109/323 (33%), Gaps = 77/323 (23%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSY-SQAPSQYSQQSSSYGQQS-SFRQDHP 272
GQ G + GQQ G P +P GS ++ P ++ + G++ Q P
Sbjct: 1367 GQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLP 1426
Query: 273 SSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGG 332
GV G++ G G ++GPD GR G G G G G MG AG+RG
Sbjct: 1427 GPRGVVGRQ--GLEG------IAGPDGLP-GRDG-QAGQQGEQGDDGDPGPMGPAGKRGN 1476
Query: 333 FNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKR 392
G P + GPP E + G + R
Sbjct: 1477 PGVAGLPGAQ------GPPGFKGESGLPGQLGPPGKRGT------------------EGR 1512
Query: 393 TGQPMIHIYLDKETGKP--KGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPP 450
TG P G+P KG S E G L K P
Sbjct: 1513 TGLP-------GNQGEPGSKGQPGDSGE-----------------MGFPGMAGLFGPKGP 1548
Query: 451 MNSMRGGLPPREGRGMPPPLRGGPG--------GPGGPGGPMGRMGGRGGDRGGFPPRGP 502
+ G +G PP L G G GP G GP G G RG D G PRGP
Sbjct: 1549 PGDI--GFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRG-DWGLQGPRGP 1605
Query: 503 RGSRGNPS----GGGNVQHRAGD 521
G RG P GG +Q + D
Sbjct: 1606 PGPRGRPGPPGPPGGPIQLQQDD 1628
Score = 31.6 bits (70), Expect = 2.4
Identities = 45/170 (26%), Positives = 63/170 (37%), Gaps = 21/170 (12%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 274
G P + G+ S GQ G+ +P G + P G Q
Sbjct: 1514 GLPGNQGEPGSKGQPGDSGEM---GFPGMAGLFG--PKGPPGDIGFKGIQGP-----RGP 1563
Query: 275 MGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFN 334
G+ G+E G GP + GP +G D+G G G RG G G G
Sbjct: 1564 PGLMGKE--GIVGP---LGILGPSGLPGPKG--DKGSRGDWGLQGPRGPPGPRGRPGPPG 1616
Query: 335 KPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLN--DSVTLDDLADFFK 382
PGGP+ D DLG D+ + A+ + + D + LD + FK
Sbjct: 1617 PPGGPIQLQQD-DLGAAFQTWMDT-SGALRPESYSYPDRLVLDQGGEIFK 1664
>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
Length = 1499
Score = 91.3 bits (225), Expect = 3e-18
Identities = 148/542 (27%), Positives = 183/542 (33%), Gaps = 116/542 (21%)
Query: 116 SAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQV 175
S + P A P PQ + ET P G P L P
Sbjct: 377 SGFPGNPGMKGEAGPTGARGPEGPQ--GQRGETGPP----GPVGSPGLPGAIGTDGTPGA 430
Query: 176 PGSYPMQPVTAPP-SYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQ 234
G + PP S P Q ++ Q Q G P G+ G+ +G
Sbjct: 431 KGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGI 490
Query: 235 QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSM 294
Q P P + G + P ++G G G G NR
Sbjct: 491 QGPIGPPGEEGKRGP-------------------RGDPGTVGPPGPV--GERGAPGNRGF 529
Query: 295 SGPDNRGRGRGGF-DRGGMSRGGRGGGRGGMGSAGERG---GFNKPGGPMDEGPDLDLGP 350
G D +G +RG + G G +G G GE G G P +GP+ LGP
Sbjct: 530 PGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGP 589
Query: 351 PVDPDEDS---DNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETG 407
P ED +I ++G S+ G+ +G P G
Sbjct: 590 LGAPGEDGRPGPPGSIGIRGQPGSM------------GLPGPKGSSGDP----------G 627
Query: 408 KP--KGDATVSYEDPPTAKAAVEWFDGKDFQ-GSKLKVSLARKKPPMNSMRGGLPPREGR 464
KP G+A V P + A GKD + G V PP GL G
Sbjct: 628 KPGEAGNAGV-----PGQRGA----PGKDGEVGPSGPVG-----PP------GLAGERGE 667
Query: 465 GMPPPLRGGPG--GPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAG 520
PP G G GP GP G G+ G +G GD G P GPRG RGNP G
Sbjct: 668 QGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERG------- 720
Query: 521 DWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMD 580
PG E P+G P P P G G GP G++G G
Sbjct: 721 -----EPGI----TGLPGEKGMAGGHGPDG--PKGSPGPSGTPGDTGPPGLQGMPGERGI 769
Query: 581 RGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRG--GPGGPPGPLMEQMGGRRGGRGG 638
G PG GDRGG G +G + G RG GP GPPGP G G +G
Sbjct: 770 AGTPGPK------GDRGGI-GEKGAEGTAGNDGARGLPGPLGPPGP-----AGPTGEKGE 817
Query: 639 PG 640
PG
Sbjct: 818 PG 819
Score = 90.9 bits (224), Expect = 3e-18
Identities = 143/493 (29%), Positives = 171/493 (34%), Gaps = 118/493 (23%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 274
G P + G + G Q G+ P P + G R P S
Sbjct: 567 GLPGARGLTGNPGVQGPEGKLGPLGAPGEDG----------------------RPGPPGS 604
Query: 275 MGVYGQESGGFSGPGENRSMSGPDNRGR-GRGGF--DRGGMSRGGRGGGRGGMGS---AG 328
+G+ GQ G PG S P G G G RG + G G G +G AG
Sbjct: 605 IGIRGQP-GSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAG 663
Query: 329 ERGGFNKPGG------PMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFK 382
ERG PG P GP + G P D D A+ G
Sbjct: 664 ERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERG--- 720
Query: 383 QCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKV 442
+ G+ + G H D G P T PP QG +
Sbjct: 721 EPGITGLPGEKGMAGGH-GPDGPKGSPGPSGTPGDTGPP------------GLQGMPGER 767
Query: 443 SLARKKPPMNSMRGGLPPR--EG-------RGMPPPLRGGPGGPGGPGGPMGRMGGRGGD 493
+A P RGG+ + EG RG+P PL GP GP GP G G G RG
Sbjct: 768 GIAGTPGPKGD-RGGIGEKGAEGTAGNDGARGLPGPL--GPPGPAGPTGEKGEPGPRG-- 822
Query: 494 RGGFPPRGPRGSRGNP-SGGGNVQHRAGDWQCPNPGCGNQNFAWRT----ECNQCKAPKP 548
GP GSRGNP S G N A + P G + +P P
Sbjct: 823 -----LVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGP 877
Query: 549 EGFLPPPFP-----------------PPG-----GDRGRGGPGGMRGGRG-----GLMDR 581
+G P P PPG G GR GP G G G G +
Sbjct: 878 QGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGK 937
Query: 582 GGPGGMFRG-----GRGGDRG--GFRGGRGMDRGGFGGGRRGGPGGPPGPL-------ME 627
GP G+ RG GR GDRG G GG G D+G G + GP GPPGP +
Sbjct: 938 EGPPGL-RGDPGSHGRVGDRGPAGPPGGPG-DKGDPGEDGQPGPDGPPGPAGTTGQRGIV 995
Query: 628 QMGGRRGGRGGPG 640
M G+RG RG PG
Sbjct: 996 GMPGQRGERGMPG 1008
Score = 87.8 bits (216), Expect = 3e-17
Identities = 133/459 (28%), Positives = 166/459 (36%), Gaps = 79/459 (17%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 274
G P S G+ G + G P P + G P Q ++G P
Sbjct: 315 GAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLG--PQGAPGQRGAHGMPGK-----PGP 367
Query: 275 MGVYG-QESGGFSGPGENRSMSGPDN-RG----RGRGGFDRGGMSRGGRGGGRGGMGSAG 328
MG G S GF G + +GP RG +G+ G + G G G G +G+ G
Sbjct: 368 MGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRG-ETGPPGPVGSPGLPGAIGTDG 426
Query: 329 ERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVK 388
G G P GP GPP P QG+ + F + G
Sbjct: 427 TPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGP---QGIRGQPGDPGVPGFKGEAGP-- 481
Query: 389 MNKRTGQPMIH-----IYLDKETGK--PKGD-ATVSYEDPPTAKAAV--EWFDGKDF--- 435
G+P H I E GK P+GD TV P + A F G D
Sbjct: 482 ----KGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPG 537
Query: 436 -QGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPG--GPGGPMGRMGGRGG 492
+G++ + P S G P R G P RG G PG GP G +G +G G
Sbjct: 538 PKGAQGERGPVGSSGPKGSQ--GDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGE 595
Query: 493 DRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPG-CGNQNFAWRTECNQCKAPKPEGF 551
D PP G G RG P G + PG GN Q AP +G
Sbjct: 596 DGRPGPP-GSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVP-----GQRGAPGKDGE 649
Query: 552 LPP--PFPPPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDR 607
+ P P PPG G+RG GP G G +G G PG GG+ GD+G
Sbjct: 650 VGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPG---EGGKPGDQGV--------- 697
Query: 608 GGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGE 646
G G GPL G RG RG PG ++GE
Sbjct: 698 --------PGDPGAVGPL-----GPRGERGNPG--ERGE 721
Score = 86.7 bits (213), Expect = 6e-17
Identities = 116/437 (26%), Positives = 149/437 (34%), Gaps = 51/437 (11%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 274
G P S G + G + G + P + G Q + S+ + +
Sbjct: 135 GPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQ 194
Query: 275 MGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFN 334
M ++SG S G GP RG G+ GG G G GE G
Sbjct: 195 MAGLDEKSGLGSQVGLMPGSVGPVG--------PRGPQGLQGQQGGAGPTGPPGEPGDPG 246
Query: 335 KPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTG 394
G GP+ GPP P ED + G F G+ + G
Sbjct: 247 PMGPIGSRGPE---GPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRG 303
Query: 395 QPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSM 454
H L+ G+ + P A+ + G + + L + P
Sbjct: 304 ----HKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGR--LGPQGAPGQRG 357
Query: 455 RGGLPPREGRGMPPPLRGGPGGPGGPG-----GPMGRMGGRG--GDRGGFPPRGPRGSRG 507
G+P + G P + G G PG PG GP G G G G RG P GP GS G
Sbjct: 358 AHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPG 417
Query: 508 NPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGG 567
P G +PG P G PP P G +G G
Sbjct: 418 LPGAIGTDGTPGAKGPTGSPGTSG----------------PPGSAGPPGSP--GPQGSTG 459
Query: 568 PGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRGGPG--GPPG 623
P G+RG G D G PG G G+ G G +G G G RG PG GPPG
Sbjct: 460 PQGIRGQPG---DPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPG 516
Query: 624 PLMEQMGGRRGGRGGPG 640
P+ E+ G G RG PG
Sbjct: 517 PVGER--GAPGNRGFPG 531
Score = 81.3 bits (199), Expect = 3e-15
Identities = 124/447 (27%), Positives = 143/447 (31%), Gaps = 103/447 (23%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 274
G P S G+ G G Q P P G + P Q S Q +
Sbjct: 831 GNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGE-PGQKGDAGSPGPQGLAGSPGPHGP 889
Query: 275 MGVYGQESG----------GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRG-GRGGGRGG 323
GV G + G GF G GP G G G G G
Sbjct: 890 NGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGS 949
Query: 324 MGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQ 383
G G+RG PGGP D+G D G P D G Q
Sbjct: 950 HGRVGDRGPAGPPGGPGDKG---DPGEDGQPGPDGPPGPAGTTG---------------Q 991
Query: 384 CGVVKMNKRTGQPMIHIYLDKETGKP--KGDATVSYEDPPTAKAAVEWFDGKDFQGSKLK 441
G+V M + G E G P G A + PT
Sbjct: 992 RGIVGMPGQRG----------ERGMPGLPGPAGTPGKVGPTG------------------ 1023
Query: 442 VSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG--GRGGDRGGFPP 499
+ K PP G + P G P GP GP G G GR G G GDRG P
Sbjct: 1024 -ATGDKGPP-----GPVGPPGSNG--PVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGP 1075
Query: 500 RGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPP 559
G GS+G P G V Q +PG P PP
Sbjct: 1076 AGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRG-----------------------PIGPP 1112
Query: 560 G--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRR 615
G G RG GP G RG +G DRG G G G +G G G G ++G G
Sbjct: 1113 GRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNG-EQGSAGIPGP 1171
Query: 616 GGPGGPPGPLMEQMGGRRGGRGGPGKM 642
GP GPPGP+ G G G PG +
Sbjct: 1172 FGPRGPPGPV-----GPSGKEGNPGPL 1193
Score = 80.9 bits (198), Expect = 3e-15
Identities = 150/538 (27%), Positives = 179/538 (33%), Gaps = 128/538 (23%)
Query: 176 PGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQ 235
PG Q + PP P + Q G P + G G++ + G++
Sbjct: 671 PGPTGFQGLPGPPGPPG-----------EGGKPGDQGVPGDPGAVGPLGPRGERGNPGER 719
Query: 236 PPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESG-GFSG-PGENRS 293
G A G + P G G G G PGE
Sbjct: 720 GEPGITGLPGEKGMAG----------GHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGI 769
Query: 294 MSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPG--GPMDE----GPDLD 347
P +G DRGG+ G G G G+ G G PG GP E GP
Sbjct: 770 AGTPGPKG------DRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGL 823
Query: 348 LGPP---VDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDK 404
+GPP +P +N G D GQP +
Sbjct: 824 VGPPGSRGNPGSRGENGPTGAVGFAGPQGPD------------------GQPGV----KG 861
Query: 405 ETGKP--KGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPRE 462
E G+P KGDA P A G + LK + PP + G P
Sbjct: 862 EPGEPGQKGDAG---SPGPQGLAGSPGPHGPNGVPG-LKGGRGTQGPPGAT---GFPGSA 914
Query: 463 GRGMPPPLRGGPGGPGGPGGPMGRMGGRG-----GDRGGFPPRGPRGSRGNPSGGGNVQH 517
GR PP GP G GP GP+G G G GD G G RG G P G G+
Sbjct: 915 GRVGPP----GPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGD 970
Query: 518 RAGDWQCPNP-------GCGNQNF-----AWRTECNQCKAPKPEGFLPPPFPPPG--GDR 563
D Q P P G Q R E P P G P P G GD+
Sbjct: 971 PGEDGQ-PGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAG-TPGKVGPTGATGDK 1028
Query: 564 GRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFG---------- 611
G GP G G G + + G G G G G G RG RG D G G
Sbjct: 1029 GPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRG-DPGPAGLPGSQGAPGT 1087
Query: 612 ---------GGRRGGPG--GPPGPLMEQMGGRRGGRGGPG----KMDKGEHRQERRDR 654
G+RG PG GP GP GR G RG PG + DKG+H +R DR
Sbjct: 1088 PGPVGAPGDAGQRGDPGSRGPIGP-----PGRAGKRGLPGPQGPRGDKGDH-GDRGDR 1139
Score = 79.0 bits (193), Expect = 1e-14
Identities = 154/607 (25%), Positives = 201/607 (33%), Gaps = 129/607 (21%)
Query: 145 PTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYP--PTSYSSTQPTS 202
P + P+ G +P Q P VPG P P PP +P P ++P S
Sbjct: 136 PPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQ-PGAP--GPPGHPSHPGPDGLSRPFS 192
Query: 203 YDQSSYSQQNTYGQ-----PSSYGQQSSYGQQSSYGQQP---PTSYPPQTGSY------- 247
+ +++ G P S G G Q GQQ PT P + G
Sbjct: 193 AQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIG 252
Query: 248 SQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESG-GFSGP----------------GE 290
S+ P + G+ R +P +G G GF G G
Sbjct: 253 SRGPEGPPGKPGEDGEPG--RNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGP 310
Query: 291 NRSMSGPDNRGRGRGGFDRGGMS----RG--GRGGGRGGMGSAGERGGFNKPGGPMDEGP 344
+ P ++G G M RG G G G G+ G+RG PG P GP
Sbjct: 311 KGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGP 370
Query: 345 ---------------DLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKM 389
+ GP + G V L G
Sbjct: 371 LGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGA 430
Query: 390 NKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKD-------FQGSKLKV 442
TG P T P G A P + G+ F+G
Sbjct: 431 KGPTGSP--------GTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGE---- 478
Query: 443 SLARKKPPMNSMRG--GLPPREGRGMPPPLRGGPG--GPGGPGGPMGRMGGRG------- 491
+ + +P + ++G G P EG+ P RG PG GP GP G G G RG
Sbjct: 479 AGPKGEPGPHGIQGPIGPPGEEGKRGP---RGDPGTVGPPGPVGERGAPGNRGFPGSDGL 535
Query: 492 -------GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCK 544
G+RG GP+GS+G+P G NPG +
Sbjct: 536 PGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPE----GKLGPLG 591
Query: 545 APKPEGFLPPPFPPPG-GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----G 598
AP +G P PP G RG+ G G+ G +G D G PG G G RG G
Sbjct: 592 APGEDG---RPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDG 648
Query: 599 FRGGRG-MDRGGFGG--GRRGGPG--------GPPGPLMEQMGGRRGGR---GGPGKMDK 644
G G + G G G +G PG GPPGP E GG+ G + G PG +
Sbjct: 649 EVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGE--GGKPGDQGVPGDPGAVGP 706
Query: 645 GEHRQER 651
R ER
Sbjct: 707 LGPRGER 713
Score = 70.1 bits (170), Expect = 6e-12
Identities = 122/419 (29%), Positives = 152/419 (36%), Gaps = 85/419 (20%)
Query: 296 GPDNRGRGRGGFD---------RGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDL 346
G N GRGR G G R G G G G GERG +PG +G D
Sbjct: 103 GNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDG 162
Query: 347 DLGPPVD---PDEDSDNSAIYVQGLN-----DSVTLDDLADFFKQCGVVKMNKRTGQPMI 398
+ G P P S GL+ LD+ + Q G++ + P
Sbjct: 163 EPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRG 222
Query: 399 HIYLDKETG--------------KPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSL 444
L + G P G + P K + G++ G+ +V
Sbjct: 223 PQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRN--GNPGEVGF 280
Query: 445 ARKKPPMNSMRG--GLPPREG----RGMPPPLRGGPGGPG-----GPGGPMGRMG----- 488
A P G GLP +G +G+ P +G G PG GP GPMG MG
Sbjct: 281 A-GSPGARGFPGAPGLPGLKGHRGHKGLEGP-KGEVGAPGSKGEAGPTGPMGAMGPLGPR 338
Query: 489 GRGGDRGGFPPR---GPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKA 545
G G+RG P+ G RG+ G P G + G P N + E A
Sbjct: 339 GMPGERGRLGPQGAPGQRGAHGMPGKPGPM----GPLGIPGSSGFPGNPGMKGEAGPTGA 394
Query: 546 PKPEG--------FLPPPFPPPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGD 595
PEG P P PG G G G G +G G G PG G G
Sbjct: 395 RGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGP 454
Query: 596 RG-----GFRGGRGMDRG--GFGG--GRRGGPG-----GPPGPLMEQMGGRRGGRGGPG 640
+G G RG G D G GF G G +G PG GP GP E+ G+RG RG PG
Sbjct: 455 QGSTGPQGIRGQPG-DPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEE--GKRGPRGDPG 510
Score = 59.7 bits (143), Expect = 8e-09
Identities = 70/218 (32%), Positives = 84/218 (38%), Gaps = 24/218 (11%)
Query: 452 NSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNP 509
N RG + G+ P + G G PG P GP G G RG G +G PRGP+G G P
Sbjct: 106 NFGRGRKGQKGEPGLVPVVTGIRGRPG-PAGPPGSQGPRGERGPKGRPGPRGPQGIDGEP 164
Query: 510 S--GGGNVQHRAGDWQCPNP-GCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRG 566
G G P P G A ++ + L P P G RG
Sbjct: 165 GVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQ 224
Query: 567 GPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMD----------RGGFGG-- 612
G G +GG G G PG G G RG G G G D GF G
Sbjct: 225 GLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSP 284
Query: 613 GRRGGPGGPPGPLMEQMGGRRGGRGGPGKM----DKGE 646
G RG PG P P ++ G +G G G++ KGE
Sbjct: 285 GARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGE 322
Score = 59.3 bits (142), Expect = 1e-08
Identities = 69/237 (29%), Positives = 86/237 (36%), Gaps = 54/237 (22%)
Query: 455 RGGLPPREGRGMP--PPLRGGPGGPGGPGGP------------------MGRMGGRGGDR 494
+G PR +G+ P + G PG PG PG P + G G
Sbjct: 149 KGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQV 208
Query: 495 GGFP-------PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPK 547
G P PRGP+G +G GG G+ P P +
Sbjct: 209 GLMPGSVGPVGPRGPQGLQGQ-QGGAGPTGPPGEPGDPGP------------MGPIGSRG 255
Query: 548 PEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGM 605
PEG PP P G+ GR G G G G RG PG G G RG G G +G
Sbjct: 256 PEG--PPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKG- 312
Query: 606 DRGGFGGGRRGGPGGPPGPL-------MEQMGGRRGGRGGPGKMDKGEHRQERRDRP 655
+ G G GP GP G + M GR G +G PG+ +G H + P
Sbjct: 313 EVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQ--RGAHGMPGKPGP 367
Score = 41.2 bits (95), Expect = 0.003
Identities = 55/235 (23%), Positives = 68/235 (28%), Gaps = 28/235 (11%)
Query: 122 PAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPM 181
P P P PT P P S G +P N P G+
Sbjct: 1007 PGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGE 1066
Query: 182 QPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYP 241
+ P P S Q G P G GQ+ G + P P
Sbjct: 1067 RGDRGDPG----------PAGLPGS----QGAPGTPGPVGAPGDAGQRGDPGSRGPIGPP 1112
Query: 242 PQTGSYS-QAPSQYSQQSSSYGQQSSFRQD-HPSSMGVYG----------QESGGFSGPG 289
+ G P +G + Q H G+ G Q S G GP
Sbjct: 1113 GRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPF 1172
Query: 290 ENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGP 344
R GP G + G + G G RG +G AG G +PG P GP
Sbjct: 1173 GPRGPPGPVGPSGKEG--NPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGP 1225
Score = 37.7 bits (86), Expect = 0.034
Identities = 38/112 (33%), Positives = 42/112 (37%), Gaps = 11/112 (9%)
Query: 524 CP----NPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLM 579
CP PG GN NF K K E L P G G GP G +G RG
Sbjct: 93 CPVCSQTPGGGNTNFG-----RGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERG 147
Query: 580 DRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGG 631
+G PG RG +G D G+ G G GP G P QM G
Sbjct: 148 PKGRPGP--RGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAG 197
Score = 35.4 bits (80), Expect = 0.17
Identities = 56/250 (22%), Positives = 79/250 (31%), Gaps = 49/250 (19%)
Query: 119 GTQPAYPAYGQQPAATAPTRPQDGNKPTETSQP--------QSSTGGYNQPSLGYGQSNY 170
G ++ G + A P P D P E QP +TG + +
Sbjct: 945 GDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGER 1004
Query: 171 SYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPS---------SYG 221
P +PG P P PT + + G+P + G
Sbjct: 1005 GMPGLPG-----PAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPG 1059
Query: 222 QQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQE 281
+ + G++ G P P G AP P +G G +
Sbjct: 1060 RDGAVGERGDRGDPGPAGLPGSQG----APGT------------------PGPVGAPG-D 1096
Query: 282 SGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRG--GGRGGMGSAGERGGFNKPGGP 339
+G PG +R GP R G+ G RG +G G RG G G RG G P
Sbjct: 1097 AGQRGDPG-SRGPIGPPGRA-GKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLP 1154
Query: 340 MDEGPDLDLG 349
GP+ + G
Sbjct: 1155 GPPGPNGEQG 1164
>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
sapiens]
Length = 1650
Score = 91.3 bits (225), Expect = 3e-18
Identities = 151/565 (26%), Positives = 197/565 (34%), Gaps = 90/565 (15%)
Query: 136 PTRP--QDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPT 193
PT P Q G + T G + P G+ PQ P +P PP P
Sbjct: 756 PTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPK--GPPGPPGK 813
Query: 194 SYSSTQPTSYDQSSYS-QQNTYGQPSSYGQQSSYGQQSSYGQQP---PTSYPPQTGSYSQ 249
P + + + G P G Q + G+ G++ P P + G
Sbjct: 814 DGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGT 873
Query: 250 APSQYSQQSSSYGQQSSFRQDHPSSM-GVYGQES--GGFSGPG--ENRSMSGPDNRGRGR 304
A + ++ G + +D P+ + G G+ G GPG N SGP
Sbjct: 874 AGKEGTKGDP--GPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSP 931
Query: 305 GGFDRGGMSRGG------RGGGRGGMGSAGERG--GFNKPGGPMD----EGP---DLDLG 349
G +RG GG R G +G G+AGE+G G P GP +GP G
Sbjct: 932 G--ERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAG 989
Query: 350 PPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKP 409
PP ED D + G + K NK P G+P
Sbjct: 990 PPGVAGEDGDKGEVGDPGQKGT----------------KGNKGEHGPPGPPGPIGPVGQP 1033
Query: 410 KGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRG---- 465
+ P A+ F K +G++ PP GLP G
Sbjct: 1034 ---GAAGADGEPGARGPQGHFGAKGDEGTR-----GFNGPPGPIGLQGLPGPSGEKGETG 1085
Query: 466 ----MPPPLRGGPGGPGGPG---GPMGRMGGRG-----GDRGGFPPRGPRGSRGNPSGGG 513
M PP GP GP GP GP G GG G G++G G G +G P G
Sbjct: 1086 DVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKG 1145
Query: 514 NVQHRAGDWQCPNPG-CGNQNFAWRTECNQCKA-PKPEGFLPPPFPP----------PGG 561
R + PG G T + K P P GF P PP G
Sbjct: 1146 PRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKG 1205
Query: 562 DRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGM--DRGGFGGGRRGG 617
DRG G G G G + G PG + + G G G G +GG+G D G G + G
Sbjct: 1206 DRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1265
Query: 618 PGGPPGPLMEQMGGRRGGRGGPGKM 642
P GP GP + G G RG PG +
Sbjct: 1266 PVGPAGPAGKP--GPDGLRGLPGSV 1288
Score = 90.1 bits (222), Expect = 6e-18
Identities = 118/396 (29%), Positives = 154/396 (38%), Gaps = 68/396 (17%)
Query: 272 PSSMGVYGQESG--GFSGPGENRSMSGPDNRG--RGRGGFDRGGMSRGGRGGGRGGMGSA 327
P S G+ G ESG G GP + ++GP + RGR G D G G G G
Sbjct: 418 PGSPGLKG-ESGDLGPQGPRGPQGLTGPPGKAGRRGRAGAD-------GARGMPGDPGVK 469
Query: 328 GERGGFNKPGGPMDEGPDLDLG------PPVDPDEDSDNSAIYVQGLNDSVTLDDLADFF 381
G+RG PG P ++G D G PP + E D+ I +GL L
Sbjct: 470 GDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPK 529
Query: 382 KQCGV-----VKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQ 436
G+ V+ P + E G P T + P + A+ K Q
Sbjct: 530 GPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQ 589
Query: 437 GSKLKVSLARKKPPMNSMRG--GLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG--- 491
G KP + M G G P G+ PP +G GP GP GP+G G RG
Sbjct: 590 G----------KPGLPGMPGSDGPPGHPGKEGPPGTKGNQ-GPSGPQGPLGYPGPRGVKG 638
Query: 492 --GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPE 549
G RG +G +G G P G++ + + PG ++ PE
Sbjct: 639 VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED-------------GPE 685
Query: 550 GFLPPPFPPPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGM 605
G P G G G GP G+ G +G L G PG R G G G GF G G
Sbjct: 686 G-------PKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASG- 737
Query: 606 DRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 641
++G G + GP G GP + G+RG RG GK
Sbjct: 738 EKGARGLSGKSGPRGERGPTGPR--GQRGPRGATGK 771
Score = 85.1 bits (209), Expect = 2e-16
Identities = 140/503 (27%), Positives = 176/503 (34%), Gaps = 58/503 (11%)
Query: 173 PQVP-GSYPMQPVTAPPSYPPTSYSSTQPTSYDQ-SSYSQQNTYGQPSSYGQQSSYGQQS 230
PQ P GS Q PP T + P + ++ G+P G S G
Sbjct: 546 PQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPG 605
Query: 231 SYGQQ-PPTSYPPQTGSYSQAPSQYSQQSSSYGQQS-SFRQDHPSSMGVYGQESGGFSGP 288
G++ PP + Q S Q P Y G + H G G GF G
Sbjct: 606 HPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFP--GFKGD 663
Query: 289 ----GENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGP 344
G+ + P +RG +G G G G MG G+ G PG P +GP
Sbjct: 664 IGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGP 723
Query: 345 DLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDK 404
LG P P + A + G + G TG P
Sbjct: 724 KGSLGFPGFPGASGEKGARGLSG---------------KSGPRGERGPTG-PRGQRGPRG 767
Query: 405 ETGKPKGDATVSYEDP--PTAKAAVEWFDGKD-FQGSKLKVSLARKKPPMNSMRGGLPPR 461
TGK T + P P + + G + F G K PP + GLP
Sbjct: 768 ATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP--------KGPPGPPGKDGLPGH 819
Query: 462 EGRGMPPPLRGGPGGPGGPG--GPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNVQH 517
G+ +G G PG PG GP G G G G+RG P GP G +G P G
Sbjct: 820 PGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGT 879
Query: 518 RAGDWQCPNPG----CGNQNF-AWRTECNQCKAPKPEGFLPPPFPP----PGGDRGRGGP 568
+ PG G + F R P +G P PP G+RG G
Sbjct: 880 KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 939
Query: 569 GGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQ 628
GG G G +G PG G G++G G G D G G GP GPPG E
Sbjct: 940 GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPI-GPTGRD-GVQGPVGLPGPAGPPGVAGED 997
Query: 629 MGGRRGGRGGPG----KMDKGEH 647
G +G G PG K +KGEH
Sbjct: 998 --GDKGEVGDPGQKGTKGNKGEH 1018
Score = 82.0 bits (201), Expect = 2e-15
Identities = 134/469 (28%), Positives = 169/469 (36%), Gaps = 100/469 (21%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSY----GQQSSFRQD 270
G P S G+ G + G+ PT P G + Y G + S
Sbjct: 674 GVPGSRGED---GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSL--G 728
Query: 271 HPSSMGVYGQESG----GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGS 326
P G G++ G SGP R +GP + RG + G G GG G G
Sbjct: 729 FPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAK--GTSGGDGPHGP 786
Query: 327 AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGV 386
GERG PG G GPP P +D L Q G
Sbjct: 787 PGERG---LPGPQGPNGFPGPKGPPGPPGKDG------------------LPGHPGQRGE 825
Query: 387 VKMNKRTGQPMIHIYLDK-----ETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLK 441
V +TG P + ETG P G+ P + + GK+ G+K
Sbjct: 826 VGFQGKTGPPGPPGVVGPQGAAGETG-PMGERGHPGPPGPPGEQGLPGTAGKE--GTK-- 880
Query: 442 VSLARKKPPMNSMRGGLPPREG----RGMP-----PPLRGGPG-----GPGGPGGPMGRM 487
PP G P ++G RG P P GGPG GP GP GP G
Sbjct: 881 ---GDPGPP------GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSP 931
Query: 488 GGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKA 545
G RG G G P G G +G P AG+ P G + T + +
Sbjct: 932 GERGAAGSGGPIGPPGRPGPQGPPGA-------AGEKGVP----GEKGPIGPTGRDGVQG 980
Query: 546 PKPEGFLPPPFPPPG-----GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--- 597
P LP P PPG GD+G G G +G +G + G PG G G G
Sbjct: 981 PVG---LPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAG 1037
Query: 598 --GFRGGRGMDRGGFGG-GRRG--GPGGPPGPL-MEQMGGRRGGRGGPG 640
G G RG +G FG G G G GPPGP+ ++ + G G +G G
Sbjct: 1038 ADGEPGARG-PQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETG 1085
Score = 77.0 bits (188), Expect = 5e-14
Identities = 118/441 (26%), Positives = 149/441 (33%), Gaps = 104/441 (23%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQ-QSSSYGQQSSFRQDHPS 273
G G G + + G+ P P G Q + + + + G Q F
Sbjct: 998 GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHF------ 1051
Query: 274 SMGVYGQE-SGGFSGPGENRSMSG-PDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERG 331
G G E + GF+GP + G P G D G M G G RG G G G
Sbjct: 1052 --GAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADG 1109
Query: 332 GFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNK 391
PGG + LGPP + E ++ + +QG + GV
Sbjct: 1110 PQGPPGGVGN------LGPPGEKGEPGESGSPGIQG---------------EPGVKGPRG 1148
Query: 392 RTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPM 451
G+ KG++ E P DG P
Sbjct: 1149 ERGE--------------KGESGQPGEPGPPGPKGPTGDDG----------------PKG 1178
Query: 452 NSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG-----GRGGDRGGFPPRGPRGSR 506
N G P G PP GGP G G G G G G G G P GP G R
Sbjct: 1179 NPGPVGFPGDPG----PPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1234
Query: 507 GNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRG 566
G G+ + G +PG AP G + P G G+
Sbjct: 1235 GPAGSPGSEGRQGGKGAKGDPGA-------------IGAPGKTGPVGP-----AGPAGKP 1276
Query: 567 GPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRGGPG----- 619
GP G+RG G + +G PG + G G G G G RG D G G +G PG
Sbjct: 1277 GPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRG-DAG--AKGEKGHPGLIGLI 1333
Query: 620 GPPGPLMEQMGGRRGGRGGPG 640
GPPG EQ G +G RG PG
Sbjct: 1334 GPPG---EQ--GEKGDRGLPG 1349
Score = 72.0 bits (175), Expect = 2e-12
Identities = 107/432 (24%), Positives = 132/432 (30%), Gaps = 83/432 (19%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQSSFRQDHPS 273
G+P + G Q +G + G + P G PS ++ G P
Sbjct: 1040 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1099
Query: 274 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGF 333
G PG ++ P +G G G G RG G GE G
Sbjct: 1100 GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQP 1159
Query: 334 NKPGGPMDEGPDLDLGP---------PVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQC 384
+PG P +GP D GP P DP + G
Sbjct: 1160 GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGD------------- 1206
Query: 385 GVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSL 444
G+ D E G+P PP L
Sbjct: 1207 --------RGE-------DGEPGQPGSPGPTGENGPPGP--------------------L 1231
Query: 445 ARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG--GPMGRMGGRGGDRGGFPPRGP 502
++ P G P EGR +G PG G PG GP+G G G GP
Sbjct: 1232 GKRGP------AGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKP-------GP 1278
Query: 503 RGSRGNPSGGGNVQHRAGDWQCPNPG-CGNQNFAWRTECNQCKAPKPEGFLPPPFPPPG- 560
G RG P G Q PG G K K L PPG
Sbjct: 1279 DGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGE 1338
Query: 561 ----GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGR 614
GDRG GP G G +G + G G + GG G G G +G +G G G
Sbjct: 1339 QGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGE 1398
Query: 615 RG--GPGGPPGP 624
+G GP G PGP
Sbjct: 1399 KGVQGPPGHPGP 1410
Score = 65.1 bits (157), Expect = 2e-10
Identities = 101/352 (28%), Positives = 118/352 (33%), Gaps = 62/352 (17%)
Query: 319 GGRGGMGSAGERG----GFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTL 374
G RG G GE G G P EGP +GPP +QG V
Sbjct: 291 GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPG------------IQGNPGPVGD 338
Query: 375 DDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKD 434
+ G+ + G P + L G GD K V
Sbjct: 339 PGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGD-----------KGPVVAAQEAQ 387
Query: 435 FQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPG--GPGGPGGPMGRMG--GR 490
Q + LA + PP G P G+ P L+G G GP GP GP G G G+
Sbjct: 388 AQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGK 447
Query: 491 GGDRG--------GFPP----RGPRGSRGNPSGGGNVQHRA--GDWQCPNPGCGNQNFAW 536
G RG G P +G RG G P G HR G P P +
Sbjct: 448 AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGD 507
Query: 537 RTECNQCKAPK---PEGFL----PPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFR 589
E P P G L PP P P G RG GP G +G G + G PG
Sbjct: 508 DGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT 567
Query: 590 GGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 641
G G G +G G GP G PG + M G G G PGK
Sbjct: 568 PGTQGLPG--------PQGAIGPHGEKGPQGKPG--LPGMPGSDGPPGHPGK 609
Score = 49.7 bits (117), Expect = 9e-06
Identities = 71/236 (30%), Positives = 83/236 (35%), Gaps = 67/236 (28%)
Query: 449 PPMNSMRGGLPPREG-RGMPPPLRGGP--GGPGGPGGPMGRMGGRGGDRGGFPPRGPRGS 505
PP+ G +G +G P L G GP GP GP G +G P G
Sbjct: 283 PPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIG-------------PPGI 329
Query: 506 RGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEG---FLPPPFPPPGGD 562
+GNP G+ R + PG AP P G LP F GGD
Sbjct: 330 QGNPGPVGDPGERGPPGRAGLPGSDG-------------APGPPGTSLMLPFRFGSGGGD 376
Query: 563 RG---------------------RGGPG--GMRGGRGGLMDRGGPGGMFRGGRGGDRG-- 597
+G RG PG G G G L G PG G GD G
Sbjct: 377 KGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPG---LKGESGDLGPQ 433
Query: 598 GFRGGRGMDRGGFGGGRRG-----GPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHR 648
G RG +G+ GRRG G G PG + G RG G PG + HR
Sbjct: 434 GPRGPQGLTGPPGKAGRRGRAGADGARGMPGD--PGVKGDRGFDGLPGLPGEKGHR 487
Score = 40.4 bits (93), Expect = 0.005
Identities = 72/294 (24%), Positives = 94/294 (31%), Gaps = 51/294 (17%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 274
G+P G + G G P +P G + + Q + + P S
Sbjct: 1160 GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPR-GQDGAKGDRGEDGEPGQPGS 1218
Query: 275 MGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFN 334
G G+ +GP P G+ RG G G +GG G+ G+ G
Sbjct: 1219 PGPTGE-----NGP--------PGPLGK------RGPAGSPGSEGRQGGKGAKGDPGAIG 1259
Query: 335 KPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTG 394
PG GP GP P D ++GL SV Q G G
Sbjct: 1260 APGKTGPVGP---AGPAGKPGPDG------LRGLPGSVGQQGRPGATGQAGPPGPVGPPG 1310
Query: 395 QPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK-PPMNS 453
P + +GDA E + G+ QG K L + P
Sbjct: 1311 LPGL-----------RGDAGAKGEKGHPGLIGLIGPPGE--QGEKGDRGLPGPQGSPGQK 1357
Query: 454 MRGGLPPREGRGMP--PPLRGGPGGPGG------PGGPMGRMGGRGGDRGGFPP 499
G+P G P PP GP GP G PGGP G G +G PP
Sbjct: 1358 GEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPP 1411
>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
sapiens]
Length = 1629
Score = 91.3 bits (225), Expect = 3e-18
Identities = 151/565 (26%), Positives = 197/565 (34%), Gaps = 90/565 (15%)
Query: 136 PTRP--QDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPT 193
PT P Q G + T G + P G+ PQ P +P PP P
Sbjct: 735 PTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPK--GPPGPPGK 792
Query: 194 SYSSTQPTSYDQSSYS-QQNTYGQPSSYGQQSSYGQQSSYGQQP---PTSYPPQTGSYSQ 249
P + + + G P G Q + G+ G++ P P + G
Sbjct: 793 DGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGT 852
Query: 250 APSQYSQQSSSYGQQSSFRQDHPSSM-GVYGQES--GGFSGPG--ENRSMSGPDNRGRGR 304
A + ++ G + +D P+ + G G+ G GPG N SGP
Sbjct: 853 AGKEGTKGDP--GPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSP 910
Query: 305 GGFDRGGMSRGG------RGGGRGGMGSAGERG--GFNKPGGPMD----EGP---DLDLG 349
G +RG GG R G +G G+AGE+G G P GP +GP G
Sbjct: 911 G--ERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAG 968
Query: 350 PPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKP 409
PP ED D + G + K NK P G+P
Sbjct: 969 PPGVAGEDGDKGEVGDPGQKGT----------------KGNKGEHGPPGPPGPIGPVGQP 1012
Query: 410 KGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRG---- 465
+ P A+ F K +G++ PP GLP G
Sbjct: 1013 ---GAAGADGEPGARGPQGHFGAKGDEGTR-----GFNGPPGPIGLQGLPGPSGEKGETG 1064
Query: 466 ----MPPPLRGGPGGPGGPG---GPMGRMGGRG-----GDRGGFPPRGPRGSRGNPSGGG 513
M PP GP GP GP GP G GG G G++G G G +G P G
Sbjct: 1065 DVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKG 1124
Query: 514 NVQHRAGDWQCPNPG-CGNQNFAWRTECNQCKA-PKPEGFLPPPFPP----------PGG 561
R + PG G T + K P P GF P PP G
Sbjct: 1125 PRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKG 1184
Query: 562 DRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGM--DRGGFGGGRRGG 617
DRG G G G G + G PG + + G G G G +GG+G D G G + G
Sbjct: 1185 DRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1244
Query: 618 PGGPPGPLMEQMGGRRGGRGGPGKM 642
P GP GP + G G RG PG +
Sbjct: 1245 PVGPAGPAGKP--GPDGLRGLPGSV 1267
Score = 90.1 bits (222), Expect = 6e-18
Identities = 118/396 (29%), Positives = 154/396 (38%), Gaps = 68/396 (17%)
Query: 272 PSSMGVYGQESG--GFSGPGENRSMSGPDNRG--RGRGGFDRGGMSRGGRGGGRGGMGSA 327
P S G+ G ESG G GP + ++GP + RGR G D G G G G
Sbjct: 397 PGSPGLKG-ESGDLGPQGPRGPQGLTGPPGKAGRRGRAGAD-------GARGMPGDPGVK 448
Query: 328 GERGGFNKPGGPMDEGPDLDLG------PPVDPDEDSDNSAIYVQGLNDSVTLDDLADFF 381
G+RG PG P ++G D G PP + E D+ I +GL L
Sbjct: 449 GDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPK 508
Query: 382 KQCGV-----VKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQ 436
G+ V+ P + E G P T + P + A+ K Q
Sbjct: 509 GPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQ 568
Query: 437 GSKLKVSLARKKPPMNSMRG--GLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG--- 491
G KP + M G G P G+ PP +G GP GP GP+G G RG
Sbjct: 569 G----------KPGLPGMPGSDGPPGHPGKEGPPGTKGNQ-GPSGPQGPLGYPGPRGVKG 617
Query: 492 --GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPE 549
G RG +G +G G P G++ + + PG ++ PE
Sbjct: 618 VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED-------------GPE 664
Query: 550 GFLPPPFPPPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGM 605
G P G G G GP G+ G +G L G PG R G G G GF G G
Sbjct: 665 G-------PKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASG- 716
Query: 606 DRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 641
++G G + GP G GP + G+RG RG GK
Sbjct: 717 EKGARGLSGKSGPRGERGPTGPR--GQRGPRGATGK 750
Score = 85.1 bits (209), Expect = 2e-16
Identities = 140/503 (27%), Positives = 176/503 (34%), Gaps = 58/503 (11%)
Query: 173 PQVP-GSYPMQPVTAPPSYPPTSYSSTQPTSYDQ-SSYSQQNTYGQPSSYGQQSSYGQQS 230
PQ P GS Q PP T + P + ++ G+P G S G
Sbjct: 525 PQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPG 584
Query: 231 SYGQQ-PPTSYPPQTGSYSQAPSQYSQQSSSYGQQS-SFRQDHPSSMGVYGQESGGFSGP 288
G++ PP + Q S Q P Y G + H G G GF G
Sbjct: 585 HPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFP--GFKGD 642
Query: 289 ----GENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGP 344
G+ + P +RG +G G G G MG G+ G PG P +GP
Sbjct: 643 IGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGP 702
Query: 345 DLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDK 404
LG P P + A + G + G TG P
Sbjct: 703 KGSLGFPGFPGASGEKGARGLSG---------------KSGPRGERGPTG-PRGQRGPRG 746
Query: 405 ETGKPKGDATVSYEDP--PTAKAAVEWFDGKD-FQGSKLKVSLARKKPPMNSMRGGLPPR 461
TGK T + P P + + G + F G K PP + GLP
Sbjct: 747 ATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP--------KGPPGPPGKDGLPGH 798
Query: 462 EGRGMPPPLRGGPGGPGGPG--GPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNVQH 517
G+ +G G PG PG GP G G G G+RG P GP G +G P G
Sbjct: 799 PGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGT 858
Query: 518 RAGDWQCPNPG----CGNQNF-AWRTECNQCKAPKPEGFLPPPFPP----PGGDRGRGGP 568
+ PG G + F R P +G P PP G+RG G
Sbjct: 859 KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 918
Query: 569 GGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQ 628
GG G G +G PG G G++G G G D G G GP GPPG E
Sbjct: 919 GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPI-GPTGRD-GVQGPVGLPGPAGPPGVAGED 976
Query: 629 MGGRRGGRGGPG----KMDKGEH 647
G +G G PG K +KGEH
Sbjct: 977 --GDKGEVGDPGQKGTKGNKGEH 997
Score = 82.0 bits (201), Expect = 2e-15
Identities = 134/469 (28%), Positives = 169/469 (36%), Gaps = 100/469 (21%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSY----GQQSSFRQD 270
G P S G+ G + G+ PT P G + Y G + S
Sbjct: 653 GVPGSRGED---GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSL--G 707
Query: 271 HPSSMGVYGQESG----GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGS 326
P G G++ G SGP R +GP + RG + G G GG G G
Sbjct: 708 FPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAK--GTSGGDGPHGP 765
Query: 327 AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGV 386
GERG PG G GPP P +D L Q G
Sbjct: 766 PGERG---LPGPQGPNGFPGPKGPPGPPGKDG------------------LPGHPGQRGE 804
Query: 387 VKMNKRTGQPMIHIYLDK-----ETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLK 441
V +TG P + ETG P G+ P + + GK+ G+K
Sbjct: 805 VGFQGKTGPPGPPGVVGPQGAAGETG-PMGERGHPGPPGPPGEQGLPGTAGKE--GTK-- 859
Query: 442 VSLARKKPPMNSMRGGLPPREG----RGMP-----PPLRGGPG-----GPGGPGGPMGRM 487
PP G P ++G RG P P GGPG GP GP GP G
Sbjct: 860 ---GDPGPP------GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSP 910
Query: 488 GGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKA 545
G RG G G P G G +G P AG+ P G + T + +
Sbjct: 911 GERGAAGSGGPIGPPGRPGPQGPPGA-------AGEKGVP----GEKGPIGPTGRDGVQG 959
Query: 546 PKPEGFLPPPFPPPG-----GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--- 597
P LP P PPG GD+G G G +G +G + G PG G G G
Sbjct: 960 PVG---LPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAG 1016
Query: 598 --GFRGGRGMDRGGFGG-GRRG--GPGGPPGPL-MEQMGGRRGGRGGPG 640
G G RG +G FG G G G GPPGP+ ++ + G G +G G
Sbjct: 1017 ADGEPGARG-PQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETG 1064
Score = 77.0 bits (188), Expect = 5e-14
Identities = 118/441 (26%), Positives = 149/441 (33%), Gaps = 104/441 (23%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQ-QSSSYGQQSSFRQDHPS 273
G G G + + G+ P P G Q + + + + G Q F
Sbjct: 977 GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHF------ 1030
Query: 274 SMGVYGQE-SGGFSGPGENRSMSG-PDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERG 331
G G E + GF+GP + G P G D G M G G RG G G G
Sbjct: 1031 --GAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADG 1088
Query: 332 GFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNK 391
PGG + LGPP + E ++ + +QG + GV
Sbjct: 1089 PQGPPGGVGN------LGPPGEKGEPGESGSPGIQG---------------EPGVKGPRG 1127
Query: 392 RTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPM 451
G+ KG++ E P DG P
Sbjct: 1128 ERGE--------------KGESGQPGEPGPPGPKGPTGDDG----------------PKG 1157
Query: 452 NSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG-----GRGGDRGGFPPRGPRGSR 506
N G P G PP GGP G G G G G G G G P GP G R
Sbjct: 1158 NPGPVGFPGDPG----PPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1213
Query: 507 GNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRG 566
G G+ + G +PG AP G + P G G+
Sbjct: 1214 GPAGSPGSEGRQGGKGAKGDPGA-------------IGAPGKTGPVGP-----AGPAGKP 1255
Query: 567 GPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRGGPG----- 619
GP G+RG G + +G PG + G G G G G RG D G G +G PG
Sbjct: 1256 GPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRG-DAG--AKGEKGHPGLIGLI 1312
Query: 620 GPPGPLMEQMGGRRGGRGGPG 640
GPPG EQ G +G RG PG
Sbjct: 1313 GPPG---EQ--GEKGDRGLPG 1328
Score = 72.0 bits (175), Expect = 2e-12
Identities = 107/432 (24%), Positives = 132/432 (30%), Gaps = 83/432 (19%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQSSFRQDHPS 273
G+P + G Q +G + G + P G PS ++ G P
Sbjct: 1019 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1078
Query: 274 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGF 333
G PG ++ P +G G G G RG G GE G
Sbjct: 1079 GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQP 1138
Query: 334 NKPGGPMDEGPDLDLGP---------PVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQC 384
+PG P +GP D GP P DP + G
Sbjct: 1139 GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGD------------- 1185
Query: 385 GVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSL 444
G+ D E G+P PP L
Sbjct: 1186 --------RGE-------DGEPGQPGSPGPTGENGPPGP--------------------L 1210
Query: 445 ARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG--GPMGRMGGRGGDRGGFPPRGP 502
++ P G P EGR +G PG G PG GP+G G G GP
Sbjct: 1211 GKRGP------AGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKP-------GP 1257
Query: 503 RGSRGNPSGGGNVQHRAGDWQCPNPG-CGNQNFAWRTECNQCKAPKPEGFLPPPFPPPG- 560
G RG P G Q PG G K K L PPG
Sbjct: 1258 DGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGE 1317
Query: 561 ----GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGR 614
GDRG GP G G +G + G G + GG G G G +G +G G G
Sbjct: 1318 QGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGE 1377
Query: 615 RG--GPGGPPGP 624
+G GP G PGP
Sbjct: 1378 KGVQGPPGHPGP 1389
Score = 65.1 bits (157), Expect = 2e-10
Identities = 101/352 (28%), Positives = 118/352 (33%), Gaps = 62/352 (17%)
Query: 319 GGRGGMGSAGERG----GFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTL 374
G RG G GE G G P EGP +GPP +QG V
Sbjct: 270 GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPG------------IQGNPGPVGD 317
Query: 375 DDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKD 434
+ G+ + G P + L G GD K V
Sbjct: 318 PGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGD-----------KGPVVAAQEAQ 366
Query: 435 FQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPG--GPGGPGGPMGRMG--GR 490
Q + LA + PP G P G+ P L+G G GP GP GP G G G+
Sbjct: 367 AQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGK 426
Query: 491 GGDRG--------GFPP----RGPRGSRGNPSGGGNVQHRA--GDWQCPNPGCGNQNFAW 536
G RG G P +G RG G P G HR G P P +
Sbjct: 427 AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGD 486
Query: 537 RTECNQCKAPK---PEGFL----PPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFR 589
E P P G L PP P P G RG GP G +G G + G PG
Sbjct: 487 DGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT 546
Query: 590 GGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 641
G G G +G G GP G PG + M G G G PGK
Sbjct: 547 PGTQGLPG--------PQGAIGPHGEKGPQGKPG--LPGMPGSDGPPGHPGK 588
Score = 40.4 bits (93), Expect = 0.005
Identities = 72/294 (24%), Positives = 94/294 (31%), Gaps = 51/294 (17%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 274
G+P G + G G P +P G + + Q + + P S
Sbjct: 1139 GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPR-GQDGAKGDRGEDGEPGQPGS 1197
Query: 275 MGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFN 334
G G+ +GP P G+ RG G G +GG G+ G+ G
Sbjct: 1198 PGPTGE-----NGP--------PGPLGK------RGPAGSPGSEGRQGGKGAKGDPGAIG 1238
Query: 335 KPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTG 394
PG GP GP P D ++GL SV Q G G
Sbjct: 1239 APGKTGPVGP---AGPAGKPGPDG------LRGLPGSVGQQGRPGATGQAGPPGPVGPPG 1289
Query: 395 QPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK-PPMNS 453
P + +GDA E + G+ QG K L + P
Sbjct: 1290 LPGL-----------RGDAGAKGEKGHPGLIGLIGPPGE--QGEKGDRGLPGPQGSPGQK 1336
Query: 454 MRGGLPPREGRGMP--PPLRGGPGGPGG------PGGPMGRMGGRGGDRGGFPP 499
G+P G P PP GP GP G PGGP G G +G PP
Sbjct: 1337 GEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPP 1390
Score = 35.4 bits (80), Expect = 0.17
Identities = 40/122 (32%), Positives = 45/122 (36%), Gaps = 28/122 (22%)
Query: 550 GFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMD--- 606
G L P P G G GP G++G G + D G G R G G G G G
Sbjct: 287 GMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGA-PGPPGTSLML 345
Query: 607 --RGGFGGGRRG-------------------GPGGPPGPLMEQMGGRRGGRGGPGKMD-K 644
R G GGG +G GPPGP+ GR G G PG K
Sbjct: 346 PFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPM--GYTGRPGPLGQPGSPGLK 403
Query: 645 GE 646
GE
Sbjct: 404 GE 405
>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
sapiens]
Length = 1736
Score = 91.3 bits (225), Expect = 3e-18
Identities = 151/565 (26%), Positives = 197/565 (34%), Gaps = 90/565 (15%)
Query: 136 PTRP--QDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPT 193
PT P Q G + T G + P G+ PQ P +P PP P
Sbjct: 842 PTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPK--GPPGPPGK 899
Query: 194 SYSSTQPTSYDQSSYS-QQNTYGQPSSYGQQSSYGQQSSYGQQP---PTSYPPQTGSYSQ 249
P + + + G P G Q + G+ G++ P P + G
Sbjct: 900 DGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGT 959
Query: 250 APSQYSQQSSSYGQQSSFRQDHPSSM-GVYGQES--GGFSGPG--ENRSMSGPDNRGRGR 304
A + ++ G + +D P+ + G G+ G GPG N SGP
Sbjct: 960 AGKEGTKGDP--GPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSP 1017
Query: 305 GGFDRGGMSRGG------RGGGRGGMGSAGERG--GFNKPGGPMD----EGP---DLDLG 349
G +RG GG R G +G G+AGE+G G P GP +GP G
Sbjct: 1018 G--ERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAG 1075
Query: 350 PPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKP 409
PP ED D + G + K NK P G+P
Sbjct: 1076 PPGVAGEDGDKGEVGDPGQKGT----------------KGNKGEHGPPGPPGPIGPVGQP 1119
Query: 410 KGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRG---- 465
+ P A+ F K +G++ PP GLP G
Sbjct: 1120 ---GAAGADGEPGARGPQGHFGAKGDEGTR-----GFNGPPGPIGLQGLPGPSGEKGETG 1171
Query: 466 ----MPPPLRGGPGGPGGPG---GPMGRMGGRG-----GDRGGFPPRGPRGSRGNPSGGG 513
M PP GP GP GP GP G GG G G++G G G +G P G
Sbjct: 1172 DVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKG 1231
Query: 514 NVQHRAGDWQCPNPG-CGNQNFAWRTECNQCKA-PKPEGFLPPPFPP----------PGG 561
R + PG G T + K P P GF P PP G
Sbjct: 1232 PRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKG 1291
Query: 562 DRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGM--DRGGFGGGRRGG 617
DRG G G G G + G PG + + G G G G +GG+G D G G + G
Sbjct: 1292 DRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTG 1351
Query: 618 PGGPPGPLMEQMGGRRGGRGGPGKM 642
P GP GP + G G RG PG +
Sbjct: 1352 PVGPAGPAGKP--GPDGLRGLPGSV 1374
Score = 90.1 bits (222), Expect = 6e-18
Identities = 118/396 (29%), Positives = 154/396 (38%), Gaps = 68/396 (17%)
Query: 272 PSSMGVYGQESG--GFSGPGENRSMSGPDNRG--RGRGGFDRGGMSRGGRGGGRGGMGSA 327
P S G+ G ESG G GP + ++GP + RGR G D G G G G
Sbjct: 504 PGSPGLKG-ESGDLGPQGPRGPQGLTGPPGKAGRRGRAGAD-------GARGMPGDPGVK 555
Query: 328 GERGGFNKPGGPMDEGPDLDLG------PPVDPDEDSDNSAIYVQGLNDSVTLDDLADFF 381
G+RG PG P ++G D G PP + E D+ I +GL L
Sbjct: 556 GDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPK 615
Query: 382 KQCGV-----VKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQ 436
G+ V+ P + E G P T + P + A+ K Q
Sbjct: 616 GPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQ 675
Query: 437 GSKLKVSLARKKPPMNSMRG--GLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG--- 491
G KP + M G G P G+ PP +G GP GP GP+G G RG
Sbjct: 676 G----------KPGLPGMPGSDGPPGHPGKEGPPGTKGNQ-GPSGPQGPLGYPGPRGVKG 724
Query: 492 --GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPE 549
G RG +G +G G P G++ + + PG ++ PE
Sbjct: 725 VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED-------------GPE 771
Query: 550 GFLPPPFPPPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGM 605
G P G G G GP G+ G +G L G PG R G G G GF G G
Sbjct: 772 G-------PKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASG- 823
Query: 606 DRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 641
++G G + GP G GP + G+RG RG GK
Sbjct: 824 EKGARGLSGKSGPRGERGPTGPR--GQRGPRGATGK 857
Score = 85.1 bits (209), Expect = 2e-16
Identities = 140/503 (27%), Positives = 176/503 (34%), Gaps = 58/503 (11%)
Query: 173 PQVP-GSYPMQPVTAPPSYPPTSYSSTQPTSYDQ-SSYSQQNTYGQPSSYGQQSSYGQQS 230
PQ P GS Q PP T + P + ++ G+P G S G
Sbjct: 632 PQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPG 691
Query: 231 SYGQQ-PPTSYPPQTGSYSQAPSQYSQQSSSYGQQS-SFRQDHPSSMGVYGQESGGFSGP 288
G++ PP + Q S Q P Y G + H G G GF G
Sbjct: 692 HPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFP--GFKGD 749
Query: 289 ----GENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGP 344
G+ + P +RG +G G G G MG G+ G PG P +GP
Sbjct: 750 IGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGP 809
Query: 345 DLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDK 404
LG P P + A + G + G TG P
Sbjct: 810 KGSLGFPGFPGASGEKGARGLSG---------------KSGPRGERGPTG-PRGQRGPRG 853
Query: 405 ETGKPKGDATVSYEDP--PTAKAAVEWFDGKD-FQGSKLKVSLARKKPPMNSMRGGLPPR 461
TGK T + P P + + G + F G K PP + GLP
Sbjct: 854 ATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP--------KGPPGPPGKDGLPGH 905
Query: 462 EGRGMPPPLRGGPGGPGGPG--GPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNVQH 517
G+ +G G PG PG GP G G G G+RG P GP G +G P G
Sbjct: 906 PGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGT 965
Query: 518 RAGDWQCPNPG----CGNQNF-AWRTECNQCKAPKPEGFLPPPFPP----PGGDRGRGGP 568
+ PG G + F R P +G P PP G+RG G
Sbjct: 966 KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 1025
Query: 569 GGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQ 628
GG G G +G PG G G++G G G D G G GP GPPG E
Sbjct: 1026 GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPI-GPTGRD-GVQGPVGLPGPAGPPGVAGED 1083
Query: 629 MGGRRGGRGGPG----KMDKGEH 647
G +G G PG K +KGEH
Sbjct: 1084 --GDKGEVGDPGQKGTKGNKGEH 1104
Score = 82.0 bits (201), Expect = 2e-15
Identities = 134/469 (28%), Positives = 169/469 (36%), Gaps = 100/469 (21%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSY----GQQSSFRQD 270
G P S G+ G + G+ PT P G + Y G + S
Sbjct: 760 GVPGSRGED---GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSL--G 814
Query: 271 HPSSMGVYGQESG----GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGS 326
P G G++ G SGP R +GP + RG + G G GG G G
Sbjct: 815 FPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAK--GTSGGDGPHGP 872
Query: 327 AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGV 386
GERG PG G GPP P +D L Q G
Sbjct: 873 PGERG---LPGPQGPNGFPGPKGPPGPPGKDG------------------LPGHPGQRGE 911
Query: 387 VKMNKRTGQPMIHIYLDK-----ETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLK 441
V +TG P + ETG P G+ P + + GK+ G+K
Sbjct: 912 VGFQGKTGPPGPPGVVGPQGAAGETG-PMGERGHPGPPGPPGEQGLPGTAGKE--GTK-- 966
Query: 442 VSLARKKPPMNSMRGGLPPREG----RGMP-----PPLRGGPG-----GPGGPGGPMGRM 487
PP G P ++G RG P P GGPG GP GP GP G
Sbjct: 967 ---GDPGPP------GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSP 1017
Query: 488 GGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKA 545
G RG G G P G G +G P AG+ P G + T + +
Sbjct: 1018 GERGAAGSGGPIGPPGRPGPQGPPGA-------AGEKGVP----GEKGPIGPTGRDGVQG 1066
Query: 546 PKPEGFLPPPFPPPG-----GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--- 597
P LP P PPG GD+G G G +G +G + G PG G G G
Sbjct: 1067 PVG---LPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAG 1123
Query: 598 --GFRGGRGMDRGGFGG-GRRG--GPGGPPGPL-MEQMGGRRGGRGGPG 640
G G RG +G FG G G G GPPGP+ ++ + G G +G G
Sbjct: 1124 ADGEPGARG-PQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETG 1171
Score = 77.0 bits (188), Expect = 5e-14
Identities = 118/441 (26%), Positives = 149/441 (33%), Gaps = 104/441 (23%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQ-QSSSYGQQSSFRQDHPS 273
G G G + + G+ P P G Q + + + + G Q F
Sbjct: 1084 GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHF------ 1137
Query: 274 SMGVYGQE-SGGFSGPGENRSMSG-PDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERG 331
G G E + GF+GP + G P G D G M G G RG G G G
Sbjct: 1138 --GAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADG 1195
Query: 332 GFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNK 391
PGG + LGPP + E ++ + +QG + GV
Sbjct: 1196 PQGPPGGVGN------LGPPGEKGEPGESGSPGIQG---------------EPGVKGPRG 1234
Query: 392 RTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPM 451
G+ KG++ E P DG P
Sbjct: 1235 ERGE--------------KGESGQPGEPGPPGPKGPTGDDG----------------PKG 1264
Query: 452 NSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG-----GRGGDRGGFPPRGPRGSR 506
N G P G PP GGP G G G G G G G G P GP G R
Sbjct: 1265 NPGPVGFPGDPG----PPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1320
Query: 507 GNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRG 566
G G+ + G +PG AP G + P G G+
Sbjct: 1321 GPAGSPGSEGRQGGKGAKGDPGA-------------IGAPGKTGPVGP-----AGPAGKP 1362
Query: 567 GPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRGGPG----- 619
GP G+RG G + +G PG + G G G G G RG D G G +G PG
Sbjct: 1363 GPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRG-DAG--AKGEKGHPGLIGLI 1419
Query: 620 GPPGPLMEQMGGRRGGRGGPG 640
GPPG EQ G +G RG PG
Sbjct: 1420 GPPG---EQ--GEKGDRGLPG 1435
Score = 72.0 bits (175), Expect = 2e-12
Identities = 107/432 (24%), Positives = 132/432 (30%), Gaps = 83/432 (19%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQSSFRQDHPS 273
G+P + G Q +G + G + P G PS ++ G P
Sbjct: 1126 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1185
Query: 274 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGF 333
G PG ++ P +G G G G RG G GE G
Sbjct: 1186 GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQP 1245
Query: 334 NKPGGPMDEGPDLDLGP---------PVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQC 384
+PG P +GP D GP P DP + G
Sbjct: 1246 GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGD------------- 1292
Query: 385 GVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSL 444
G+ D E G+P PP L
Sbjct: 1293 --------RGE-------DGEPGQPGSPGPTGENGPPGP--------------------L 1317
Query: 445 ARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG--GPMGRMGGRGGDRGGFPPRGP 502
++ P G P EGR +G PG G PG GP+G G G GP
Sbjct: 1318 GKRGP------AGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKP-------GP 1364
Query: 503 RGSRGNPSGGGNVQHRAGDWQCPNPG-CGNQNFAWRTECNQCKAPKPEGFLPPPFPPPG- 560
G RG P G Q PG G K K L PPG
Sbjct: 1365 DGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGE 1424
Query: 561 ----GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGR 614
GDRG GP G G +G + G G + GG G G G +G +G G G
Sbjct: 1425 QGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGE 1484
Query: 615 RG--GPGGPPGP 624
+G GP G PGP
Sbjct: 1485 KGVQGPPGHPGP 1496
Score = 68.6 bits (166), Expect = 2e-11
Identities = 123/506 (24%), Positives = 162/506 (32%), Gaps = 95/506 (18%)
Query: 173 PQVPGSYPMQPVTAPPSYPPTS--YSSTQPTSYDQSSYSQQNTYGQPSSYGQQS------ 224
PQ S +P P PT Y +P YD + Y P+ ++
Sbjct: 248 PQQQPSRLHRPQNQEPQSQPTESLYYDYEPPYYDVMTTGTTPDYQDPTPGEEEEILESSL 307
Query: 225 --SYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQ--QSSSYGQQSSFRQDHPSSMGVYGQ 280
++ + Q PPT+ Q Y + + + +YG +R++ + +
Sbjct: 308 LPPLEEEQTDLQVPPTADRFQAEEYGEGGTDPPEGPYDYTYGYGDDYREETELGPALSAE 367
Query: 281 ESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPM 340
+ + R + G +G GM G G G G G G PG
Sbjct: 368 TAHSGAAAHGPRGLKGE----KGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVG 423
Query: 341 DEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHI 400
D G + GPP + G+ + G P +
Sbjct: 424 DPG---ERGPP------------------------------GRAGLPGSDGAPGPPGTSL 450
Query: 401 YLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPP 460
L G GD K V Q + LA + PP G P
Sbjct: 451 MLPFRFGSGGGD-----------KGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPG 499
Query: 461 REGRGMPPPLRGGPG--GPGGPGGPMGRMG--GRGGDRG--------GFPP----RGPRG 504
G+ P L+G G GP GP GP G G G+ G RG G P +G RG
Sbjct: 500 PLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRG 559
Query: 505 SRGNPSGGGNVQHRA--GDWQCPNPGCGNQNFAWRTECNQCKAPK---PEGFL----PPP 555
G P G HR G P P + E P P G L PP
Sbjct: 560 FDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPG 619
Query: 556 FPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRR 615
P P G RG GP G +G G + G PG G G G +G G
Sbjct: 620 IPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPG--------PQGAIGPHGE 671
Query: 616 GGPGGPPGPLMEQMGGRRGGRGGPGK 641
GP G PG + M G G G PGK
Sbjct: 672 KGPQGKPG--LPGMPGSDGPPGHPGK 695
Score = 40.4 bits (93), Expect = 0.005
Identities = 72/294 (24%), Positives = 94/294 (31%), Gaps = 51/294 (17%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 274
G+P G + G G P +P G + + Q + + P S
Sbjct: 1246 GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPR-GQDGAKGDRGEDGEPGQPGS 1304
Query: 275 MGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFN 334
G G+ +GP P G+ RG G G +GG G+ G+ G
Sbjct: 1305 PGPTGE-----NGP--------PGPLGK------RGPAGSPGSEGRQGGKGAKGDPGAIG 1345
Query: 335 KPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTG 394
PG GP GP P D ++GL SV Q G G
Sbjct: 1346 APGKTGPVGP---AGPAGKPGPDG------LRGLPGSVGQQGRPGATGQAGPPGPVGPPG 1396
Query: 395 QPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK-PPMNS 453
P + +GDA E + G+ QG K L + P
Sbjct: 1397 LPGL-----------RGDAGAKGEKGHPGLIGLIGPPGE--QGEKGDRGLPGPQGSPGQK 1443
Query: 454 MRGGLPPREGRGMP--PPLRGGPGGPGG------PGGPMGRMGGRGGDRGGFPP 499
G+P G P PP GP GP G PGGP G G +G PP
Sbjct: 1444 GEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPP 1497
Score = 36.2 bits (82), Expect = 0.098
Identities = 56/199 (28%), Positives = 64/199 (32%), Gaps = 44/199 (22%)
Query: 473 GPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQ 532
G GG P GP G G D GP S G G
Sbjct: 333 GEGGTDPPEGPYDYTYGYGDDYREETELGPALSAETAHSGAAAHGPRG------------ 380
Query: 533 NFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGR 592
+ E + +P G L P P G G GP G++G G + D G G R G
Sbjct: 381 ---LKGEKGEPAVLEP-GMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 436
Query: 593 GGDRGGFRGGRGMD-----RGGFGGGRRG-------------------GPGGPPGPLMEQ 628
G G G G R G GGG +G GPPGP+
Sbjct: 437 PGSDGA-PGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPM--G 493
Query: 629 MGGRRGGRGGPGKMD-KGE 646
GR G G PG KGE
Sbjct: 494 YTGRPGPLGQPGSPGLKGE 512
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 89.7 bits (221), Expect = 7e-18
Identities = 146/567 (25%), Positives = 182/567 (32%), Gaps = 83/567 (14%)
Query: 119 GTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGS 178
G Q A G Q P P +G KP + P G P L + +P GS
Sbjct: 654 GEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVP----GEAGAPGLVGPRGERGFPGERGS 709
Query: 179 YPMQPVTAPPSYP-------PTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSS 231
Q + P P P S Q Q G+ + G G +
Sbjct: 710 PGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD 769
Query: 232 YGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGE 290
G++ P P + G P + + G++ P+ +G PGE
Sbjct: 770 VGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAG------SAGARGAPGE 823
Query: 291 NRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGP 350
R +GP G GF G G+ G +G G AG++G PG +GP GP
Sbjct: 824 -RGETGPP----GPAGF-AGPPGADGQPGAKGEQGEAGQKGDAGAPG---PQGPSGAPGP 874
Query: 351 PVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGK-- 408
A QG + A + G N G P K+ K
Sbjct: 875 QGPTGVTGPKGARGAQGPPGATGFPGAAG---RVGPPGSNGNPGPPGPPGPSGKDGPKGA 931
Query: 409 -----PKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRG-----GL 458
P G A P + G D A P + G GL
Sbjct: 932 RGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSG------AEGPPGPQGLAGQRGIVGL 985
Query: 459 PPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHR 518
P + G P L G G PG G P G GDRG P GP G G G
Sbjct: 986 PGQRGERGFPGLPGPSGEPGKQGAP-----GASGDRGPPGPVGPPGLTGPAGEPGREGSP 1040
Query: 519 AGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGG------DRGRGG----- 567
D G R E AP G PP P P G DRG G
Sbjct: 1041 GADGPPGRDGAAGVK-GDRGETGAVGAPGAPG--PPGSPGPAGPTGKQGDRGEAGAQGPM 1097
Query: 568 -PGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGM--------DRGGFGGG 613
P G G RG +G G G G+RG GF G +G+ D+G G
Sbjct: 1098 GPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPA 1157
Query: 614 RRGGPGGPPGPLMEQMGGRRGGRGGPG 640
GP GPPGP+ G+ G G PG
Sbjct: 1158 GPSGPRGPPGPV--GPSGKDGANGIPG 1182
Score = 84.3 bits (207), Expect = 3e-16
Identities = 109/375 (29%), Positives = 130/375 (34%), Gaps = 46/375 (12%)
Query: 288 PGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLD 347
PG+ + + GP +G G RG RG +G G+ G RG +PG P + GP
Sbjct: 109 PGDIKDIVGPKGPPGPQGPAGEQG-PRGDRGD-KGEKGAPGPRGRDGEPGTPGNPGPPGP 166
Query: 348 LGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQ-----PMIHIYL 402
GPP P + +A G ++ L G + G P
Sbjct: 167 PGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGN 226
Query: 403 DKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRG-----G 457
E G+P + PP G D + K + R P RG G
Sbjct: 227 PGEPGEPGVSGPMGPRGPPGPPGK----PGDDGEAGKPGKAGERGPPGPQGARGFPGTPG 282
Query: 458 LPPREGRGMPPPLRGGPGGPGGPGGPMGRMG--GRGGDRGGFPPRGPRGSRGNPSGGGNV 515
LP +G P L G G G PG G G G G G PRG G RG G
Sbjct: 283 LPGVKGHRGYPGLDGAKGEAGAPG-VKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAA 341
Query: 516 QHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPP-FPPPGGDRGRGGPGGMRGG 574
R D Q P P P P G P FP G +G GP G RG
Sbjct: 342 GARGNDGQ-PGPA---------------GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGP 385
Query: 575 RGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGMDRGGFGGGRRG--GPGGPPGPLME 627
G RG PG G G G G G +G G G GP GPPGP
Sbjct: 386 EGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGP-QG 444
Query: 628 QMG--GRRGGRGGPG 640
G G +G G PG
Sbjct: 445 ATGPLGPKGQTGEPG 459
Score = 83.6 bits (205), Expect = 5e-16
Identities = 141/559 (25%), Positives = 181/559 (32%), Gaps = 99/559 (17%)
Query: 125 PAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPG---SYPM 181
P + P A P P P+ G P N +PG S
Sbjct: 365 PGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGA 424
Query: 182 QPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYP 241
+ P +P + Q G GQ G G+Q P P
Sbjct: 425 PGIAGAPGFPGP-----------RGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP 473
Query: 242 PQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRG 301
G AP ++ G++ + + P +G G G G NR G D
Sbjct: 474 GPAGPQG-APGPAGEE----GKRGA--RGEPGGVGPIGPP--GERGAPGNRGFPGQDGLA 524
Query: 302 RGRGG-FDRGGMSRGGRGGGRGGMGSAGERG---GFNKPGGPMDEGPDLDLGPPVDPDED 357
+G +RG G G G G GE G G P D GP +GP P ED
Sbjct: 525 GPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGED 584
Query: 358 SDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSY 417
QG GQP + + + G+ +
Sbjct: 585 GRPGPPGPQGAR------------------------GQPGVMGFPGPKGAN--GEPGKAG 618
Query: 418 EDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGP 477
E + GKD + PP + G +G P +G PG P
Sbjct: 619 EKGLPGAPGLRGLPGKDGE-------TGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPP 671
Query: 478 GGPGGPMGRMGGRGGDRG-----GFPPR-GPRGSRGNPS--GGGNVQHRAGDWQCPN-PG 528
G PG GG+ GD+G G P GPRG RG P G Q G P PG
Sbjct: 672 GPPGE-----GGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPG 726
Query: 529 CGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMF 588
A P +G PP G+RG G G +G RG + ++G G
Sbjct: 727 TDGPKGA----SGPAGPPGAQG--PPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPG 780
Query: 589 R-GGRG--------GDRG--GFRGGRGMDRGGFGGGRRGGPG-----GPPGPLMEQMGGR 632
+ GGRG G G G +G G G RG PG GPPGP G
Sbjct: 781 KDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGP--AGFAGP 838
Query: 633 RGGRGGPG-KMDKGEHRQE 650
G G PG K ++GE Q+
Sbjct: 839 PGADGQPGAKGEQGEAGQK 857
Score = 81.3 bits (199), Expect = 3e-15
Identities = 118/424 (27%), Positives = 149/424 (35%), Gaps = 64/424 (15%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSS-FRQDHPS 273
GQP + G+Q GQ+ G P P Q P+ + + G Q P
Sbjct: 843 GQPGAKGEQGEAGQKGDAGAPGPQG--PSGAPGPQGPTGVTGPKGARGAQGPPGATGFPG 900
Query: 274 SMGVYGQE-SGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGG 332
+ G G S G GP SG D RG D G R G G +G G GE+G
Sbjct: 901 AAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARG--DSGPPGRAGEPGLQGPAGPPGEKG- 957
Query: 333 FNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKR 392
+PG D+GP GPP QGL + L + G +
Sbjct: 958 --EPG---DDGPSGAEGPPGP------------QGLAGQRGIVGLPGQRGERGFPGLPGP 1000
Query: 393 TGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMN 452
+G+P GK +G S + P G + + + S PP
Sbjct: 1001 SGEP----------GK-QGAPGASGDRGPPGPVGPPGLTGPAGEPGR-EGSPGADGPPGR 1048
Query: 453 SMRGGLPPREGRGMPPPLRGGPGGPGGPG--GPMGRMGGRG--GDRGGFPPRGPRGSRG- 507
G+ G G PG PG PG GP G+ G RG G +G P GP G+RG
Sbjct: 1049 DGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGI 1108
Query: 508 -NPSGGGNVQHRAGDWQCPNPG----CGNQNFAWRTECNQCKAPKPEGFLPPPFPPPG-- 560
P G + AG+ PG G++ F P + P P G
Sbjct: 1109 QGPQGPRGDKGEAGE-----PGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPR 1163
Query: 561 GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGG 620
G G GP G G G G PG GR G+ G G G GP G
Sbjct: 1164 GPPGPVGPSGKDGANGIPGPIGPPGPR---GRSGETG--------PAGPPGNPGPPGPPG 1212
Query: 621 PPGP 624
PPGP
Sbjct: 1213 PPGP 1216
Score = 80.9 bits (198), Expect = 3e-15
Identities = 137/542 (25%), Positives = 176/542 (32%), Gaps = 114/542 (21%)
Query: 111 SYAAQSAYG--TQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQS 168
++AAQ A G + G P P+ P PQ G +P G+
Sbjct: 178 NFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEP----GEP 233
Query: 169 NYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQ 228
S P P P PP P + +P + G P G + G
Sbjct: 234 GVSGPMGPRGPP-----GPPGKPGDDGEAGKP--------GKAGERGPPGPQGARGFPGT 280
Query: 229 QSSYGQQPPTSYPPQTGSYSQAPSQ-YSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSG 287
G + YP G+ +A + +S S G+ S P MG G
Sbjct: 281 PGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGS-----PGPMGPRGL------- 328
Query: 288 PGENRSMSGPDNRGRGRGGFDRGGMSRG-GRGGGRGGMGSAGERGGFNKPGGPMDEGPDL 346
PGE R +GP RG + G + G G GG G G G + G GP+
Sbjct: 329 PGE-RGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEG 387
Query: 347 DLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKET 406
GP +P G + + D + G + G P
Sbjct: 388 AQGPRGEPGTPGSPGPA---GASGNPGTDGIPGAKGSAGAPGIAGAPGFP---------- 434
Query: 407 GKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGM 466
P+G PP + A K G +P + +G P+ G
Sbjct: 435 -GPRG--------PPGPQGATGPLGPKGQTG----------EPGIAGFKGEQGPK---GE 472
Query: 467 PPPLRGGPGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQC 524
P GP GP G GP G G RG G+ GG P GP G RG P
Sbjct: 473 P-----GPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAP--------------- 512
Query: 525 PNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPP-PGGDRGRGGPGGMRGGRGGLMDRGG 583
GN+ F P +G P P G G GP G G G + G
Sbjct: 513 -----GNRGF-----------PGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGL 556
Query: 584 PGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPG----PLMEQMGGRRGGRGGP 639
PG GR GD G G+ G G R GP GP G P + G +G G P
Sbjct: 557 PGARGLTGRPGDAG--PQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEP 614
Query: 640 GK 641
GK
Sbjct: 615 GK 616
Score = 78.6 bits (192), Expect = 2e-14
Identities = 130/461 (28%), Positives = 156/461 (33%), Gaps = 78/461 (16%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 274
G P + G G G+ P+ P + G P Q + + P
Sbjct: 555 GLPGARGLTGRPGDAGPQGKVGPSGAPGEDGR----PGPPGPQGA---------RGQPGV 601
Query: 275 MGVYGQESGGFSGPGENRSMSGPDNRG-RGRGGFDRGGMSRGGRGGGRGGMGSAGERGGF 333
MG G + G PG+ P G RG G D G G G G AGERG
Sbjct: 602 MGFPGPK-GANGEPGKAGEKGLPGAPGLRGLPGKD----GETGAAGPPGPAGPAGERGEQ 656
Query: 334 NKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRT 393
PG +G GPP + + D G V F + G
Sbjct: 657 GAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQ 716
Query: 394 GQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNS 453
G + G P D P A + G + +A K
Sbjct: 717 GPRGL-------PGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD 769
Query: 454 M--RG--GLPPREG-RGMPPPLRGGPGGPGG---------PGGPMGRMGGRG--GDRGGF 497
+ +G G P ++G RG+ P+ GP GP G P GP G G RG G+RG
Sbjct: 770 VGEKGPEGAPGKDGGRGLTGPI--GPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGET 827
Query: 498 PPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGC-GNQNFAWRTECNQCKAPKPEGFLPPPF 556
P GP G G P G PG G Q A + AP P+G P
Sbjct: 828 GPPGPAGFAGPPGADGQ------------PGAKGEQGEAGQK--GDAGAPGPQG--PSGA 871
Query: 557 PPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGMD----- 606
P P G G GP G RG +G G PG R G G G G G G D
Sbjct: 872 PGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGA 931
Query: 607 RGGFG-GGRRG-----GPGGPPGPLMEQ-MGGRRGGRGGPG 640
RG G GR G GP GPPG E G G G PG
Sbjct: 932 RGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPG 972
Score = 77.4 bits (189), Expect = 4e-14
Identities = 120/461 (26%), Positives = 150/461 (32%), Gaps = 95/461 (20%)
Query: 215 GQPSSYGQQSSYGQ-QSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQD-HP 272
GQP GQ+ G + G + P PQ + Q P G +D P
Sbjct: 98 GQPGPKGQKGEPGDIKDIVGPKGPPG--PQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 155
Query: 273 SSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDR--------------GGMSRGGRG 318
+ G G G GP + G + + GGFD G M G
Sbjct: 156 GTPGNPGPP--GPPGPPGPPGLGG-NFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPP 212
Query: 319 GGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLA 378
G G G G +G +PG P GP GPP P + D+ G
Sbjct: 213 GPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPG----------- 261
Query: 379 DFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPP-----TAKAAVEWFDGK 433
+ G E G P + P DG
Sbjct: 262 -------------KAG----------ERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGA 298
Query: 434 DFQGSKLKVSLARKKPPMNSMRG-----GLPPREGRGMPPPLRGGPG-----GPGGPGGP 483
+ V P N G GLP GR P G G GP GP GP
Sbjct: 299 KGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGP 358
Query: 484 MGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECN 541
+G GG G G G GP G+RG P G + G P P + N
Sbjct: 359 VGPAGGPGFPGAPGAKGEAGPTGARG-PEGAQGPRGEPGTPGSPGPAGASGN-------- 409
Query: 542 QCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GF 599
P +G P G G G G G RG +G G + G+ G+ G GF
Sbjct: 410 ----PGTDGI--PGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGF 463
Query: 600 RGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPG 640
+G ++G G GP G PGP E+ G+RG RG PG
Sbjct: 464 KG----EQGPKGEPGPAGPQGAPGPAGEE--GKRGARGEPG 498
Score = 77.0 bits (188), Expect = 5e-14
Identities = 149/542 (27%), Positives = 181/542 (33%), Gaps = 100/542 (18%)
Query: 131 PAATAPTRPQDGNK-PTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPS 189
PA A R DG P P GG P + G Q P
Sbjct: 337 PAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPG 396
Query: 190 YPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYP-PQTGSYS 248
P S P + T G P + G + G + G P P PQ +
Sbjct: 397 TP----GSPGPAG----ASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGP 448
Query: 249 QAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESG-GFSGPGENRSMSGPDNRGRGRGGF 307
P GQ P G G++ G GP + GP
Sbjct: 449 LGPK---------GQTGE-----PGIAGFKGEQGPKGEPGPAGPQGAPGP---------- 484
Query: 308 DRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQG 367
G + G G GG+G G G PG G D GP P E + +G
Sbjct: 485 -AGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKG 543
Query: 368 LNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAV 427
N R G+P + TG+P GDA P K
Sbjct: 544 ANGD------------------PGRPGEPGLP-GARGLTGRP-GDA------GPQGKVGP 577
Query: 428 EWFDGKDFQGSKLKVSLARKKPPMNSMRG-----GLPPREG-RGMP--PPLRGGPG---- 475
G+D + AR +P + G G P + G +G+P P LRG PG
Sbjct: 578 SGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGE 637
Query: 476 ----GPGGPGGPMGRMGGRG--GDRG--GFP-PRGPRGSRGNPSGGGNVQHRAGDWQCPN 526
GP GP GP G G +G G G G P P GP G G P G V AG
Sbjct: 638 TGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKP-GDQGVPGEAGAPGLVG 696
Query: 527 PGCGNQNFAWRTECNQCKAPK-PEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPG 585
P G + F + + P G P P G +G GP G G +G +G PG
Sbjct: 697 PR-GERGFPGERGSPGAQGLQGPRGL--PGTPGTDGPKGASGPAGPPGAQGPPGLQGMPG 753
Query: 586 GMFRGGRG-----GDRG--GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGG 638
RG G GDRG G +G G G GG GP GPPGP G +G G
Sbjct: 754 E--RGAAGIAGPKGDRGDVGEKGPEGAP-GKDGGRGLTGPIGPPGP--AGANGEKGEVGP 808
Query: 639 PG 640
PG
Sbjct: 809 PG 810
Score = 73.9 bits (180), Expect = 4e-13
Identities = 70/196 (35%), Positives = 80/196 (40%), Gaps = 14/196 (7%)
Query: 460 PREGRGMPPPLRG--GPGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNV 515
P+ +G P ++ GP GP GP GP G G RG GD+G GPRG G P GN
Sbjct: 102 PKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNP 161
Query: 516 QHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPE-GFLPPPFPPPGGDRGRGGPGGMRGG 574
PG G A KA + G + P P G RG GP G G
Sbjct: 162 GPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPM-GPRGPPGPAGAPGP 220
Query: 575 RGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGR 632
+G + G PG G G RG G G G D G G + G GPPGP G
Sbjct: 221 QGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPG-DDGEAGKPGKAGERGPPGP-----QGA 274
Query: 633 RGGRGGPGKMDKGEHR 648
RG G PG HR
Sbjct: 275 RGFPGTPGLPGVKGHR 290
Score = 50.8 bits (120), Expect = 4e-06
Identities = 61/195 (31%), Positives = 72/195 (36%), Gaps = 45/195 (23%)
Query: 473 GPGGPGGPGGPMGRMGGRGGDRGGFPPRGP------RGSRGNPSGGGNVQHRAGDWQCPN 526
G GP G G G + G +G P+GP RG RG+ G R D +
Sbjct: 98 GQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGT 157
Query: 527 PGCGNQNFAWRTECNQCKAPKPEGFLPPPFPP-----------PGGDRGRGGP--GGMRG 573
PG P P G PP PP G D GG G M+G
Sbjct: 158 PG----------------NPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQG 201
Query: 574 GRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRR 633
G + RG PG G G + GF+G G + G G GP GPPGP G+
Sbjct: 202 PMGPMGPRGPPG---PAGAPGPQ-GFQGNPG-EPGEPGVSGPMGPRGPPGP-----PGKP 251
Query: 634 GGRGGPGKMDKGEHR 648
G G GK K R
Sbjct: 252 GDDGEAGKPGKAGER 266
Score = 37.0 bits (84), Expect = 0.058
Identities = 38/152 (25%), Positives = 52/152 (34%), Gaps = 19/152 (12%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS----QAPSQYSQQSSSYGQQSSFRQD 270
G P G G + G Q P G+ Q P ++ G++ +
Sbjct: 1074 GSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGL--KG 1131
Query: 271 HPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRG-------- 322
H G+ G G GP ++ SGP RG G + G+ G G
Sbjct: 1132 HRGFTGLQGLP--GPPGPSGDQGASGPAGPSGPRG--PPGPVGPSGKDGANGIPGPIGPP 1187
Query: 323 -GMGSAGERGGFNKPGGPMDEGPDLDLGPPVD 353
G +GE G PG P GP GP +D
Sbjct: 1188 GPRGRSGETGPAGPPGNPGPPGPPGPPGPGID 1219
Score = 36.2 bits (82), Expect = 0.098
Identities = 97/440 (22%), Positives = 129/440 (29%), Gaps = 91/440 (20%)
Query: 105 VTTTQASYAAQSAYGTQPAYPAYGQ--QPAATAPTRPQDGNKPTETSQPQSSTGGYNQPS 162
VT + + AQ G A G+ P + P P+ P+ + G P
Sbjct: 880 VTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPG 939
Query: 163 LGYGQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQ 222
G+ P P +P PS + Q Q+ G P G+
Sbjct: 940 RA-GEPGLQGPAGPPGEKGEPGDDGPS-------GAEGPPGPQGLAGQRGIVGLPGQRGE 991
Query: 223 QSSYGQQSSYGQQPPTSYPPQTGSYSQ----APSQYSQQSSSYGQQSSFRQDHP----SS 274
+ G G+ P +G P + + G++ S D P +
Sbjct: 992 RGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGA 1051
Query: 275 MGVYGQ--ESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGG 332
GV G E+G PG P G DRG G +G MG +G G
Sbjct: 1052 AGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRG------EAGAQGPMGPSGPAGA 1105
Query: 333 FNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKR 392
G +GP D G +P E +GL G +
Sbjct: 1106 RGIQG---PQGPRGDKGEAGEPGE---------RGLKG------------HRGFTGLQGL 1141
Query: 393 TGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMN 452
G P P GD S P+ G K N
Sbjct: 1142 PGPP-----------GPSGDQGASGPAGPSGPRGPPGPVGPS------------GKDGAN 1178
Query: 453 SMRGGLPP-----REGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGS-- 505
+ G + P R G P G PG PG PG P G G D F GPR
Sbjct: 1179 GIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPP-----GPGIDMSAFAGLGPREKGP 1233
Query: 506 ------RGNPSGGGNVQHRA 519
R + + GG QH A
Sbjct: 1234 DPLQYMRADQAAGGLRQHDA 1253
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 89.7 bits (221), Expect = 7e-18
Identities = 146/567 (25%), Positives = 182/567 (32%), Gaps = 83/567 (14%)
Query: 119 GTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGS 178
G Q A G Q P P +G KP + P G P L + +P GS
Sbjct: 585 GEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVP----GEAGAPGLVGPRGERGFPGERGS 640
Query: 179 YPMQPVTAPPSYP-------PTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSS 231
Q + P P P S Q Q G+ + G G +
Sbjct: 641 PGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD 700
Query: 232 YGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGE 290
G++ P P + G P + + G++ P+ +G PGE
Sbjct: 701 VGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAG------SAGARGAPGE 754
Query: 291 NRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGP 350
R +GP G GF G G+ G +G G AG++G PG +GP GP
Sbjct: 755 -RGETGPP----GPAGF-AGPPGADGQPGAKGEQGEAGQKGDAGAPG---PQGPSGAPGP 805
Query: 351 PVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGK-- 408
A QG + A + G N G P K+ K
Sbjct: 806 QGPTGVTGPKGARGAQGPPGATGFPGAAG---RVGPPGSNGNPGPPGPPGPSGKDGPKGA 862
Query: 409 -----PKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRG-----GL 458
P G A P + G D A P + G GL
Sbjct: 863 RGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSG------AEGPPGPQGLAGQRGIVGL 916
Query: 459 PPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHR 518
P + G P L G G PG G P G GDRG P GP G G G
Sbjct: 917 PGQRGERGFPGLPGPSGEPGKQGAP-----GASGDRGPPGPVGPPGLTGPAGEPGREGSP 971
Query: 519 AGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGG------DRGRGG----- 567
D G R E AP G PP P P G DRG G
Sbjct: 972 GADGPPGRDGAAGVK-GDRGETGAVGAPGAPG--PPGSPGPAGPTGKQGDRGEAGAQGPM 1028
Query: 568 -PGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGM--------DRGGFGGG 613
P G G RG +G G G G+RG GF G +G+ D+G G
Sbjct: 1029 GPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPA 1088
Query: 614 RRGGPGGPPGPLMEQMGGRRGGRGGPG 640
GP GPPGP+ G+ G G PG
Sbjct: 1089 GPSGPRGPPGPV--GPSGKDGANGIPG 1113
Score = 84.3 bits (207), Expect = 3e-16
Identities = 109/375 (29%), Positives = 130/375 (34%), Gaps = 46/375 (12%)
Query: 288 PGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLD 347
PG+ + + GP +G G RG RG +G G+ G RG +PG P + GP
Sbjct: 40 PGDIKDIVGPKGPPGPQGPAGEQG-PRGDRGD-KGEKGAPGPRGRDGEPGTPGNPGPPGP 97
Query: 348 LGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQ-----PMIHIYL 402
GPP P + +A G ++ L G + G P
Sbjct: 98 PGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGN 157
Query: 403 DKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRG-----G 457
E G+P + PP G D + K + R P RG G
Sbjct: 158 PGEPGEPGVSGPMGPRGPPGPPGK----PGDDGEAGKPGKAGERGPPGPQGARGFPGTPG 213
Query: 458 LPPREGRGMPPPLRGGPGGPGGPGGPMGRMG--GRGGDRGGFPPRGPRGSRGNPSGGGNV 515
LP +G P L G G G PG G G G G G PRG G RG G
Sbjct: 214 LPGVKGHRGYPGLDGAKGEAGAPG-VKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAA 272
Query: 516 QHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPP-FPPPGGDRGRGGPGGMRGG 574
R D Q P P P P G P FP G +G GP G RG
Sbjct: 273 GARGNDGQ-PGPA---------------GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGP 316
Query: 575 RGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGMDRGGFGGGRRG--GPGGPPGPLME 627
G RG PG G G G G G +G G G GP GPPGP
Sbjct: 317 EGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGP-QG 375
Query: 628 QMG--GRRGGRGGPG 640
G G +G G PG
Sbjct: 376 ATGPLGPKGQTGEPG 390
Score = 83.6 bits (205), Expect = 5e-16
Identities = 141/559 (25%), Positives = 181/559 (32%), Gaps = 99/559 (17%)
Query: 125 PAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPG---SYPM 181
P + P A P P P+ G P N +PG S
Sbjct: 296 PGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGA 355
Query: 182 QPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYP 241
+ P +P + Q G GQ G G+Q P P
Sbjct: 356 PGIAGAPGFPGP-----------RGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP 404
Query: 242 PQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRG 301
G AP ++ G++ + + P +G G G G NR G D
Sbjct: 405 GPAGPQG-APGPAGEE----GKRGA--RGEPGGVGPIGPP--GERGAPGNRGFPGQDGLA 455
Query: 302 RGRGG-FDRGGMSRGGRGGGRGGMGSAGERG---GFNKPGGPMDEGPDLDLGPPVDPDED 357
+G +RG G G G G GE G G P D GP +GP P ED
Sbjct: 456 GPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGED 515
Query: 358 SDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSY 417
QG GQP + + + G+ +
Sbjct: 516 GRPGPPGPQGAR------------------------GQPGVMGFPGPKGAN--GEPGKAG 549
Query: 418 EDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGP 477
E + GKD + PP + G +G P +G PG P
Sbjct: 550 EKGLPGAPGLRGLPGKDGE-------TGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPP 602
Query: 478 GGPGGPMGRMGGRGGDRG-----GFPPR-GPRGSRGNPS--GGGNVQHRAGDWQCPN-PG 528
G PG GG+ GD+G G P GPRG RG P G Q G P PG
Sbjct: 603 GPPGE-----GGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPG 657
Query: 529 CGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMF 588
A P +G PP G+RG G G +G RG + ++G G
Sbjct: 658 TDGPKGA----SGPAGPPGAQG--PPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPG 711
Query: 589 R-GGRG--------GDRG--GFRGGRGMDRGGFGGGRRGGPG-----GPPGPLMEQMGGR 632
+ GGRG G G G +G G G RG PG GPPGP G
Sbjct: 712 KDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGP--AGFAGP 769
Query: 633 RGGRGGPG-KMDKGEHRQE 650
G G PG K ++GE Q+
Sbjct: 770 PGADGQPGAKGEQGEAGQK 788
Score = 81.3 bits (199), Expect = 3e-15
Identities = 118/424 (27%), Positives = 149/424 (35%), Gaps = 64/424 (15%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSS-FRQDHPS 273
GQP + G+Q GQ+ G P P Q P+ + + G Q P
Sbjct: 774 GQPGAKGEQGEAGQKGDAGAPGPQG--PSGAPGPQGPTGVTGPKGARGAQGPPGATGFPG 831
Query: 274 SMGVYGQE-SGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGG 332
+ G G S G GP SG D RG D G R G G +G G GE+G
Sbjct: 832 AAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARG--DSGPPGRAGEPGLQGPAGPPGEKG- 888
Query: 333 FNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKR 392
+PG D+GP GPP QGL + L + G +
Sbjct: 889 --EPG---DDGPSGAEGPPGP------------QGLAGQRGIVGLPGQRGERGFPGLPGP 931
Query: 393 TGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMN 452
+G+P GK +G S + P G + + + S PP
Sbjct: 932 SGEP----------GK-QGAPGASGDRGPPGPVGPPGLTGPAGEPGR-EGSPGADGPPGR 979
Query: 453 SMRGGLPPREGRGMPPPLRGGPGGPGGPG--GPMGRMGGRG--GDRGGFPPRGPRGSRG- 507
G+ G G PG PG PG GP G+ G RG G +G P GP G+RG
Sbjct: 980 DGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGI 1039
Query: 508 -NPSGGGNVQHRAGDWQCPNPG----CGNQNFAWRTECNQCKAPKPEGFLPPPFPPPG-- 560
P G + AG+ PG G++ F P + P P G
Sbjct: 1040 QGPQGPRGDKGEAGE-----PGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPR 1094
Query: 561 GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGG 620
G G GP G G G G PG GR G+ G G G GP G
Sbjct: 1095 GPPGPVGPSGKDGANGIPGPIGPPGPR---GRSGETG--------PAGPPGNPGPPGPPG 1143
Query: 621 PPGP 624
PPGP
Sbjct: 1144 PPGP 1147
Score = 80.9 bits (198), Expect = 3e-15
Identities = 137/542 (25%), Positives = 176/542 (32%), Gaps = 114/542 (21%)
Query: 111 SYAAQSAYG--TQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQS 168
++AAQ A G + G P P+ P PQ G +P G+
Sbjct: 109 NFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEP----GEP 164
Query: 169 NYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQ 228
S P P P PP P + +P + G P G + G
Sbjct: 165 GVSGPMGPRGPP-----GPPGKPGDDGEAGKP--------GKAGERGPPGPQGARGFPGT 211
Query: 229 QSSYGQQPPTSYPPQTGSYSQAPSQ-YSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSG 287
G + YP G+ +A + +S S G+ S P MG G
Sbjct: 212 PGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGS-----PGPMGPRGL------- 259
Query: 288 PGENRSMSGPDNRGRGRGGFDRGGMSRG-GRGGGRGGMGSAGERGGFNKPGGPMDEGPDL 346
PGE R +GP RG + G + G G GG G G G + G GP+
Sbjct: 260 PGE-RGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEG 318
Query: 347 DLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKET 406
GP +P G + + D + G + G P
Sbjct: 319 AQGPRGEPGTPGSPGPA---GASGNPGTDGIPGAKGSAGAPGIAGAPGFP---------- 365
Query: 407 GKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGM 466
P+G PP + A K G +P + +G P+ G
Sbjct: 366 -GPRG--------PPGPQGATGPLGPKGQTG----------EPGIAGFKGEQGPK---GE 403
Query: 467 PPPLRGGPGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQC 524
P GP GP G GP G G RG G+ GG P GP G RG P
Sbjct: 404 P-----GPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAP--------------- 443
Query: 525 PNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPP-PGGDRGRGGPGGMRGGRGGLMDRGG 583
GN+ F P +G P P G G GP G G G + G
Sbjct: 444 -----GNRGF-----------PGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGL 487
Query: 584 PGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPG----PLMEQMGGRRGGRGGP 639
PG GR GD G G+ G G R GP GP G P + G +G G P
Sbjct: 488 PGARGLTGRPGDAG--PQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEP 545
Query: 640 GK 641
GK
Sbjct: 546 GK 547
Score = 78.6 bits (192), Expect = 2e-14
Identities = 130/461 (28%), Positives = 156/461 (33%), Gaps = 78/461 (16%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 274
G P + G G G+ P+ P + G P Q + + P
Sbjct: 486 GLPGARGLTGRPGDAGPQGKVGPSGAPGEDGR----PGPPGPQGA---------RGQPGV 532
Query: 275 MGVYGQESGGFSGPGENRSMSGPDNRG-RGRGGFDRGGMSRGGRGGGRGGMGSAGERGGF 333
MG G + G PG+ P G RG G D G G G G AGERG
Sbjct: 533 MGFPGPK-GANGEPGKAGEKGLPGAPGLRGLPGKD----GETGAAGPPGPAGPAGERGEQ 587
Query: 334 NKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRT 393
PG +G GPP + + D G V F + G
Sbjct: 588 GAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQ 647
Query: 394 GQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNS 453
G + G P D P A + G + +A K
Sbjct: 648 GPRGL-------PGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD 700
Query: 454 M--RG--GLPPREG-RGMPPPLRGGPGGPGG---------PGGPMGRMGGRG--GDRGGF 497
+ +G G P ++G RG+ P+ GP GP G P GP G G RG G+RG
Sbjct: 701 VGEKGPEGAPGKDGGRGLTGPI--GPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGET 758
Query: 498 PPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGC-GNQNFAWRTECNQCKAPKPEGFLPPPF 556
P GP G G P G PG G Q A + AP P+G P
Sbjct: 759 GPPGPAGFAGPPGADGQ------------PGAKGEQGEAGQK--GDAGAPGPQG--PSGA 802
Query: 557 PPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGMD----- 606
P P G G GP G RG +G G PG R G G G G G G D
Sbjct: 803 PGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGA 862
Query: 607 RGGFG-GGRRG-----GPGGPPGPLMEQ-MGGRRGGRGGPG 640
RG G GR G GP GPPG E G G G PG
Sbjct: 863 RGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPG 903
Score = 78.2 bits (191), Expect = 2e-14
Identities = 114/402 (28%), Positives = 137/402 (34%), Gaps = 68/402 (16%)
Query: 287 GPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDL 346
GP GP RG DRG G G RG G G G PG P
Sbjct: 48 GPKGPPGPQGPAGEQGPRG--DRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPP------- 98
Query: 347 DLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQ-----PMIHIY 401
GPP P + +A G ++ L G + G P
Sbjct: 99 --GPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQG 156
Query: 402 LDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRG----- 456
E G+P + PP G D + K + R P RG
Sbjct: 157 NPGEPGEPGVSGPMGPRGPPGPPGK----PGDDGEAGKPGKAGERGPPGPQGARGFPGTP 212
Query: 457 GLPPREG-RGMP-----------PPLRGGPGGPGGPGGPMGRMGGRG--GDRGGFPPRGP 502
GLP +G RG P P ++G G PG G P G MG RG G+RG P G
Sbjct: 213 GLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSP-GPMGPRGLPGERGRTGPAGA 271
Query: 503 RGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPP--PG 560
G+RGN G PG A + E A PEG P P PG
Sbjct: 272 AGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGA-KGEAGPTGARGPEGAQGPRGEPGTPG 330
Query: 561 -----------------GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----G 598
G +G G G+ G G RG PG G G +G G
Sbjct: 331 SPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPG 390
Query: 599 FRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPG 640
G +G ++G G GP G PGP E+ G+RG RG PG
Sbjct: 391 IAGFKG-EQGPKGEPGPAGPQGAPGPAGEE--GKRGARGEPG 429
Score = 77.0 bits (188), Expect = 5e-14
Identities = 149/542 (27%), Positives = 181/542 (33%), Gaps = 100/542 (18%)
Query: 131 PAATAPTRPQDGNK-PTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPS 189
PA A R DG P P GG P + G Q P
Sbjct: 268 PAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPG 327
Query: 190 YPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYP-PQTGSYS 248
P S P + T G P + G + G + G P P PQ +
Sbjct: 328 TP----GSPGPAG----ASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGP 379
Query: 249 QAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESG-GFSGPGENRSMSGPDNRGRGRGGF 307
P GQ P G G++ G GP + GP
Sbjct: 380 LGPK---------GQTGE-----PGIAGFKGEQGPKGEPGPAGPQGAPGP---------- 415
Query: 308 DRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQG 367
G + G G GG+G G G PG G D GP P E + +G
Sbjct: 416 -AGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKG 474
Query: 368 LNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAV 427
N R G+P + TG+P GDA P K
Sbjct: 475 ANGD------------------PGRPGEPGLP-GARGLTGRP-GDA------GPQGKVGP 508
Query: 428 EWFDGKDFQGSKLKVSLARKKPPMNSMRG-----GLPPREG-RGMP--PPLRGGPG---- 475
G+D + AR +P + G G P + G +G+P P LRG PG
Sbjct: 509 SGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGE 568
Query: 476 ----GPGGPGGPMGRMGGRG--GDRG--GFP-PRGPRGSRGNPSGGGNVQHRAGDWQCPN 526
GP GP GP G G +G G G G P P GP G G P G V AG
Sbjct: 569 TGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKP-GDQGVPGEAGAPGLVG 627
Query: 527 PGCGNQNFAWRTECNQCKAPK-PEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPG 585
P G + F + + P G P P G +G GP G G +G +G PG
Sbjct: 628 PR-GERGFPGERGSPGAQGLQGPRGL--PGTPGTDGPKGASGPAGPPGAQGPPGLQGMPG 684
Query: 586 GMFRGGRG-----GDRG--GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGG 638
RG G GDRG G +G G G GG GP GPPGP G +G G
Sbjct: 685 E--RGAAGIAGPKGDRGDVGEKGPEGAP-GKDGGRGLTGPIGPPGP--AGANGEKGEVGP 739
Query: 639 PG 640
PG
Sbjct: 740 PG 741
Score = 73.9 bits (180), Expect = 4e-13
Identities = 70/196 (35%), Positives = 80/196 (40%), Gaps = 14/196 (7%)
Query: 460 PREGRGMPPPLRG--GPGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNV 515
P+ +G P ++ GP GP GP GP G G RG GD+G GPRG G P GN
Sbjct: 33 PKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNP 92
Query: 516 QHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPE-GFLPPPFPPPGGDRGRGGPGGMRGG 574
PG G A KA + G + P P G RG GP G G
Sbjct: 93 GPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPM-GPRGPPGPAGAPGP 151
Query: 575 RGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGR 632
+G + G PG G G RG G G G D G G + G GPPGP G
Sbjct: 152 QGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPG-DDGEAGKPGKAGERGPPGP-----QGA 205
Query: 633 RGGRGGPGKMDKGEHR 648
RG G PG HR
Sbjct: 206 RGFPGTPGLPGVKGHR 221
Score = 37.0 bits (84), Expect = 0.058
Identities = 38/152 (25%), Positives = 52/152 (34%), Gaps = 19/152 (12%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS----QAPSQYSQQSSSYGQQSSFRQD 270
G P G G + G Q P G+ Q P ++ G++ +
Sbjct: 1005 GSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGL--KG 1062
Query: 271 HPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRG-------- 322
H G+ G G GP ++ SGP RG G + G+ G G
Sbjct: 1063 HRGFTGLQGLP--GPPGPSGDQGASGPAGPSGPRG--PPGPVGPSGKDGANGIPGPIGPP 1118
Query: 323 -GMGSAGERGGFNKPGGPMDEGPDLDLGPPVD 353
G +GE G PG P GP GP +D
Sbjct: 1119 GPRGRSGETGPAGPPGNPGPPGPPGPPGPGID 1150
Score = 36.2 bits (82), Expect = 0.098
Identities = 97/440 (22%), Positives = 129/440 (29%), Gaps = 91/440 (20%)
Query: 105 VTTTQASYAAQSAYGTQPAYPAYGQ--QPAATAPTRPQDGNKPTETSQPQSSTGGYNQPS 162
VT + + AQ G A G+ P + P P+ P+ + G P
Sbjct: 811 VTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPG 870
Query: 163 LGYGQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQ 222
G+ P P +P PS + Q Q+ G P G+
Sbjct: 871 RA-GEPGLQGPAGPPGEKGEPGDDGPS-------GAEGPPGPQGLAGQRGIVGLPGQRGE 922
Query: 223 QSSYGQQSSYGQQPPTSYPPQTGSYSQ----APSQYSQQSSSYGQQSSFRQDHP----SS 274
+ G G+ P +G P + + G++ S D P +
Sbjct: 923 RGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGA 982
Query: 275 MGVYGQ--ESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGG 332
GV G E+G PG P G DRG G +G MG +G G
Sbjct: 983 AGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRG------EAGAQGPMGPSGPAGA 1036
Query: 333 FNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKR 392
G +GP D G +P E +GL G +
Sbjct: 1037 RGIQG---PQGPRGDKGEAGEPGE---------RGLKG------------HRGFTGLQGL 1072
Query: 393 TGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMN 452
G P P GD S P+ G K N
Sbjct: 1073 PGPP-----------GPSGDQGASGPAGPSGPRGPPGPVGPS------------GKDGAN 1109
Query: 453 SMRGGLPP-----REGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGS-- 505
+ G + P R G P G PG PG PG P G G D F GPR
Sbjct: 1110 GIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPP-----GPGIDMSAFAGLGPREKGP 1164
Query: 506 ------RGNPSGGGNVQHRA 519
R + + GG QH A
Sbjct: 1165 DPLQYMRADQAAGGLRQHDA 1184
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 87.8 bits (216), Expect = 3e-17
Identities = 171/691 (24%), Positives = 229/691 (33%), Gaps = 159/691 (23%)
Query: 26 TQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTATYGQTAYATSYGQPPTGYTTPTAPQA 85
T+G + Y + Y Y P D+ + T + T T AP
Sbjct: 264 TEGDGEGETYYYEYPY--YEDPEDLGKEPTPSKKPVEAAKETTEVPEELTPTPTEAAPMP 321
Query: 86 YSQPVQG----YGTGAYDTTTATVTTTQASYAAQSAYGT------QPAYPAYGQQ-PAAT 134
+ G G G YD + T + Y YG QP P G + P +T
Sbjct: 322 ETSEGAGKEEDVGIGDYDYVPSEDYYTPSPYD-DLTYGEGEENPDQPTDPGAGAEIPTST 380
Query: 135 APTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQV-PGSYPMQPVTAPPSYPPT 193
A T P G + + ++ NY P P S P + P+ T
Sbjct: 381 ADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDENYYDPYYDPTSSPSEIGPGMPANQDT 440
Query: 194 SYSST----------------QPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPP 237
Y +P + + G P G GQ G++ P
Sbjct: 441 IYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGP 500
Query: 238 TSYPPQTGSY-----------------------SQAPSQYSQQSSSYG--QQSSFRQDHP 272
P G+ S+ P +Q+S + QQ+ P
Sbjct: 501 PGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGP 560
Query: 273 SS-MGVYGQE-------SGGFSG-PGE-----NRSMSGPDNRG-----RGRGGFDRGGMS 313
+ MG+ G+ SGG G PG+ R + GP RGR G D G
Sbjct: 561 AGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSD-GARG 619
Query: 314 RGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVT 373
G+ G +G G G G + G D GP GPP P +D +
Sbjct: 620 MPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPS---GPPGPPGDDGERG------------ 664
Query: 374 LDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGK 433
DD G V G+P P+G P V DG+
Sbjct: 665 -DD--------GEVGPRGLPGEP-----------GPRGLLGPKGPPGPPGPPGVTGMDGQ 704
Query: 434 DFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGD 493
+G + P +G PP +G PG G PG P G +G G +
Sbjct: 705 P------------------GPKGNVGP-QGEPGPPGQQGNPGAQGLPG-PQGAIGPPG-E 743
Query: 494 RGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLP 553
+G P G G G P G H + P G Q P P+G P
Sbjct: 744 KG---PLGKPGLPGMPGADGPPGHPGKEG--PPGEKGGQG-----------PPGPQG--P 785
Query: 554 PPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRG--GDRG--GFRGGRGMDRGG 609
+P P G +G G G++G +G + G PG F+G G GDRG G G RG D G
Sbjct: 786 IGYPGPRGVKGADGIRGLKGTKGEKGEDGFPG--FKGDMGIKGDRGEIGPPGPRGED-GP 842
Query: 610 FGGGRRGGPGGPPGPLMEQMGGRRGGRGGPG 640
G RGGP G PGPL G +G G PG
Sbjct: 843 EGPKGRGGPNGDPGPLGPP--GEKGKLGVPG 871
Score = 82.4 bits (202), Expect = 1e-15
Identities = 127/455 (27%), Positives = 158/455 (34%), Gaps = 80/455 (17%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 274
G+ GQ+ S G + G PT PQ PS + GQQ F Q
Sbjct: 1159 GEIGEPGQKGSKGDKGEQGPPGPTG--PQGPIGQPGPSGADGEPGPRGQQGLFGQK---- 1212
Query: 275 MGVYGQESG-GFSGPGENRSMSG-PDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERG- 331
G E GF GP + G P G D G M G G RG G+ G G
Sbjct: 1213 ----GDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGP 1268
Query: 332 -----GFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGV 386
G PG ++G + G P P E +G A G
Sbjct: 1269 QGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGP 1328
Query: 387 VKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLAR 446
+ G P + + G P + PP K DG+ Q
Sbjct: 1329 PGDDGPKGSPG-PVGFPGDPGPPGEPGPAGQDGPPGDKGD----DGEPGQT--------- 1374
Query: 447 KKPPMNSMRGGLPPREGRGMP--PPLRGGPGGPGGPGGPMGRMGGRG-----GDRGGFPP 499
G P G P PP + GP GP GP G G G +G G G P
Sbjct: 1375 ----------GSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGP 1424
Query: 500 RGPRGSRGNPSGGG--NVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFP 557
GP+G+ G P G + G+ P +P P+G P P
Sbjct: 1425 IGPQGAPGKPGPDGLRGIPGPVGEQGLPG------------------SPGPDG-PPGPMG 1465
Query: 558 PPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGG 613
PPG G +G GP G + G GL+ GP G G GDRG G +G G +G G
Sbjct: 1466 PPGLPGLKGDSGPKGEK-GHPGLIGLIGPPG--EQGEKGDRGLPGPQGSSG-PKGEQGIT 1521
Query: 614 RRGGPGGPPGPL-MEQMGGRRGGRGGPGKM-DKGE 646
GP GPPGP + G +G +G G KGE
Sbjct: 1522 GPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGE 1556
Score = 81.6 bits (200), Expect = 2e-15
Identities = 142/527 (26%), Positives = 187/527 (35%), Gaps = 91/527 (17%)
Query: 176 PGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSS---YGQQSSY 232
PG M PP +P + Q Q G P G + + G + +
Sbjct: 750 PGLPGMPGADGPPGHPGKEGPPGEKGG--QGPPGPQGPIGYPGPRGVKGADGIRGLKGTK 807
Query: 233 GQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENR 292
G++ +P G + + G + + P G + G PGE
Sbjct: 808 GEKGEDGFPGFKGDMGIKGDR--GEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKG 865
Query: 293 SMSGPDNRGR----------GRGGFDRGGMSRGGRG--------GGRGGMGSAGERGG-- 332
+ P G G GF +GGRG G RG G GERG
Sbjct: 866 KLGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRG 925
Query: 333 -FNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYV---QGLNDSVTLDDLADFFKQCGVVK 388
KPG + G D GPP + + +G D L Q G
Sbjct: 926 ITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETG 985
Query: 389 MNKRTGQPMIHIYLDK-----ETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVS 443
+TG P + ETG P G+ P + + GK +G+K
Sbjct: 986 FQGKTGPPGPPGVVGPQGPTGETG-PMGERGHPGPPGPPGEQGLPGLAGK--EGTKGDPG 1042
Query: 444 LARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPR 503
A GLP ++G PP LRG PG G P GP+G +G +G + PP GP
Sbjct: 1043 PA-----------GLPGKDG---PPGLRGFPGDRGLP-GPVGALGLKGNEGPPGPP-GPA 1086
Query: 504 GSRG--NPSGGG---NVQHRAGDWQCPNPG--------CGNQNFAWRTEC-NQCKAPKPE 549
GS G P+G + R G P P G Q A R P P
Sbjct: 1087 GSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPA 1146
Query: 550 GFLPPPFPPPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--------GF 599
G P PPG GD+G G G +G +G ++G PG G G G G
Sbjct: 1147 G----PVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGP 1202
Query: 600 RGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGE 646
RG +G+ G RG P GPPGP+ G +G G PG +KGE
Sbjct: 1203 RGQQGLFGQKGDEGPRGFP-GPPGPV-----GLQGLPGPPG--EKGE 1241
Score = 78.2 bits (191), Expect = 2e-14
Identities = 116/405 (28%), Positives = 141/405 (34%), Gaps = 59/405 (14%)
Query: 268 RQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSA 327
+Q +P + G+ G + G PGE +G + + G G G G
Sbjct: 722 QQGNPGAQGLPGPQ-GAIGPPGE------------------KGPLGKPGLPGMPGADGPP 762
Query: 328 GERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDS---VTLDDLADFFKQC 384
G G PG +GP GP P A ++GL + D F
Sbjct: 763 GHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDM 822
Query: 385 GVVKMNKRTGQPMIH----IYLDKETGKPKGDATVSYEDPPTAKAAVEWFDG-KDFQGSK 439
G+ G P K G P GD K V G QG K
Sbjct: 823 GIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPK 882
Query: 440 LKVSLARKKPPMNSMRG-----GLPPREGRGMPPPLRG--GPGGPGGPGGPMGRMGGRG- 491
+ P N +G G P G+ P RG GP G G GP G GG G
Sbjct: 883 GSIGFP-GFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGP 941
Query: 492 -GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPG-CGNQNFAWRTECNQCKAPKPE 549
G G P GP+G G P G D +PG G F +T P P
Sbjct: 942 AGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKT-----GPPGPP 996
Query: 550 GFLPPPFPP----PGGDRGRGGPGGMRGGRG--GLM----DRGGPGGMFRGGRGGDRG-- 597
G + P P P G+RG GP G G +G GL +G PG G+ G G
Sbjct: 997 GVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLR 1056
Query: 598 GFRGGRGMDR--GGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPG 640
GF G RG+ G G GP GPPGP G RG G G
Sbjct: 1057 GFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSP--GERGPAGAAG 1099
Score = 72.8 bits (177), Expect = 9e-13
Identities = 118/456 (25%), Positives = 152/456 (33%), Gaps = 118/456 (25%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS----QAPSQYSQQSSSYGQQSSFRQD 270
G+P GQQ +GQ+ G + P +P G P ++ GQ
Sbjct: 1198 GEPGPRGQQGLFGQK---GDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPP 1254
Query: 271 HP----SSMGVYGQES--GGFSGPGENRSMSGPDNRGR----GRGG-----FDRGGMSRG 315
P + G G + GG PG P G G GG +RG
Sbjct: 1255 GPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGES 1314
Query: 316 GRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLD 375
G G G G G G G P G D GPP +P + +G D
Sbjct: 1315 GPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKG-------D 1367
Query: 376 DLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDF 435
D +TG P TG+P PP A E G+
Sbjct: 1368 DGEP-----------GQTGSP-------GPTGEPGPSGPPGKRGPP-GPAGPEGRQGE-- 1406
Query: 436 QGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPP--LRGGPG-----------GPGGPGG 482
+G+K + L + PP + G + P+ G P P LRG PG GP GP G
Sbjct: 1407 KGAKGEAGL--EGPPGKT--GPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPG 1462
Query: 483 PMGRMG--GRGGDRGGFPPRGPRGSRGNPS-----GGGNVQHRAGDWQCPNPGCGNQNFA 535
PMG G G GD G P+G +G+P G Q GD P P
Sbjct: 1463 PMGPPGLPGLKGDSG------PKGEKGHPGLIGLIGPPGEQGEKGDRGLPGP-------- 1508
Query: 536 WRTECNQCKAPKPEGFLPPPFPP--PGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRG 593
PK E + P P P G G GP G +G +G GP G
Sbjct: 1509 -----QGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGS----SGPTG------- 1552
Query: 594 GDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQM 629
+G G GP GPPG +++ +
Sbjct: 1553 ------------PKGEAGHPGPPGPPGPPGEVIQPL 1576
Score = 69.3 bits (168), Expect = 1e-11
Identities = 118/438 (26%), Positives = 145/438 (33%), Gaps = 90/438 (20%)
Query: 272 PSSMGVYGQESG----GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSA 327
P G G++ G G GP R +GP RG + G G GG G G
Sbjct: 888 PGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPK--GNSGGDGPAGPP 945
Query: 328 GERGGFNKPGGPMD-EGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGV 386
GERG N P GP GP GPP P +D L Q G
Sbjct: 946 GERGP-NGPQGPTGFPGPK---GPPGPPGKDG------------------LPGHPGQRGE 983
Query: 387 VKMNKRTGQPMIHIYLDKE--TGK--PKGDATVSYEDPPTAKAAVEWFDGKD-FQGSKLK 441
+TG P + + TG+ P G+ P + + GK+ +G
Sbjct: 984 TGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGP 1043
Query: 442 VSLARKKPPMNSMRG--------------GLPPREGRGMPPPLRGGPG--GPGGPGGPMG 485
L K P +RG GL EG PP G PG GP G GP+G
Sbjct: 1044 AGLPGKDGPPG-LRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIG 1102
Query: 486 RMGGRGGDRGGFPPRGPRGSRGN--PSGGGNVQHRAGDWQCPNPGC--------GNQNFA 535
+ GR G +G P G +G+ G P G G P P G++
Sbjct: 1103 -IPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEI 1161
Query: 536 WRTECNQCKAPKPEGFLPPPFPPPG-----------------------GDRGRGGPGGMR 572
K K E P P P G G +G GP G
Sbjct: 1162 GEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFP 1221
Query: 573 GGRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGMDRGGFGGGRRGGPGGPPGPLME 627
G G + +G PG G GD G G G RG G +G PGG P
Sbjct: 1222 GPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAV 1281
Query: 628 QMGGRRGGRGGPGKMDKG 645
G G G PG +G
Sbjct: 1282 GEKGEPGEAGEPGLPGEG 1299
Score = 60.5 bits (145), Expect = 5e-09
Identities = 127/504 (25%), Positives = 168/504 (33%), Gaps = 101/504 (20%)
Query: 174 QVPGSYPMQPVTAPPSYPPTSYSS--TQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSS 231
+VP P A P P TS + + Y Y PS Y +YG+
Sbjct: 305 EVPEELTPTPTEAAPM-PETSEGAGKEEDVGIGDYDYVPSEDYYTPSPY-DDLTYGE--- 359
Query: 232 YGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQES--------- 282
G++ P P G+ ++ P+ + S+S + G + +E+
Sbjct: 360 -GEENPDQ-PTDPGAGAEIPTSTADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDENYY 417
Query: 283 GGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERG----GFNKPGG 338
+ P + S GP ++ G GG RG G GE G G
Sbjct: 418 DPYYDPTSSPSEIGPGMPANQDTIYE-------GIGGPRGEKGQKGEPAIIEPGMLIEGP 470
Query: 339 PMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMI 398
P EGP GPP G + + G P
Sbjct: 471 PGPEGPAGLPGPP---------------------------------GTMGPTGQVGDPGE 497
Query: 399 HIYLDKETGKPKGDATVSYEDPPTAKAAVEW-FDGKDFQGSKLKVSLARKKPPMNSMRGG 457
G+P PP + + F G GSK + A++ ++
Sbjct: 498 R----GPPGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQA 553
Query: 458 LPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQH 517
G P L G PG G PG GG G+ G P+GPRG +G P G
Sbjct: 554 RLALRGPAGPMGLTGRPGPVGPPGS-----GGLKGEPGDVGPQGPRGVQGPPGPAGKPGR 608
Query: 518 RA---GDWQCPNPGC----GNQNFAWRT----ECNQCKAPKPEGFLPPPFPPPGGDRGRG 566
R D PG G++ F E P P G PP PP GD G
Sbjct: 609 RGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSG---PPGPP--GDDGER 663
Query: 567 GPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRGGPGGPPGP 624
G G G RG L GP G+ G G G G G GMD G G GP G PGP
Sbjct: 664 GDDGEVGPRG-LPGEPGPRGLL--GPKGPPGPPGPPGVTGMD-GQPGPKGNVGPQGEPGP 719
Query: 625 LMEQ-------MGGRRGGRGGPGK 641
+Q + G +G G PG+
Sbjct: 720 PGQQGNPGAQGLPGPQGAIGPPGE 743
Score = 51.6 bits (122), Expect = 2e-06
Identities = 96/410 (23%), Positives = 124/410 (30%), Gaps = 58/410 (14%)
Query: 136 PTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSN----YSYPQVPGSYPMQPVTAPPSY- 190
PT PQ S G Q L +GQ +P PG +Q + PP
Sbjct: 1181 PTGPQGPIGQPGPSGADGEPGPRGQQGL-FGQKGDEGPRGFPGPPGPVGLQGLPGPPGEK 1239
Query: 191 ----------PPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY 240
PP P+ + Q G P G + G++ G+
Sbjct: 1240 GETGDVGQMGPPGPPGPRGPSGAPGADGPQ----GPPGGIGNPGAVGEKGEPGEAGEPGL 1295
Query: 241 PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQES-----GGFSGPGENRSMS 295
P + G P ++ S P G G + G PG+
Sbjct: 1296 PGEGGP----PGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPG 1351
Query: 296 GPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPD 355
P G+ D+G G+ G G G G G K G P GP+ G
Sbjct: 1352 EPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKG 1411
Query: 356 E------DSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKP 409
E I QG D L G+ G P G P
Sbjct: 1412 EAGLEGPPGKTGPIGPQGAPGKPGPDGLR------GIPGPVGEQGLP----------GSP 1455
Query: 410 KGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRG--GLPPREGRGMP 467
D PP K +G + L P +G GLP +G P
Sbjct: 1456 GPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLI-GPPGEQGEKGDRGLPGPQGSSGP 1514
Query: 468 PPLRG--GPGGPGGPGGPMGRMG--GRGGDRGGFPPRGPRGSRGNPSGGG 513
+G GP GP GP GP G G G G +G P GP+G G+P G
Sbjct: 1515 KGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPG 1564
Score = 32.7 bits (73), Expect = 1.1
Identities = 55/250 (22%), Positives = 79/250 (31%), Gaps = 24/250 (9%)
Query: 121 QPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYP 180
+P P G P + + P+ + P G +P PG P
Sbjct: 1292 EPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGP-P 1350
Query: 181 MQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY 240
+P A PP D Q + G G G++ G P
Sbjct: 1351 GEPGPAGQDGPPGDKG-------DDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGR 1403
Query: 241 PPQTGSYSQAPSQYSQ-QSSSYGQQSSFRQDHPSSM----GVYGQES-GGFSGP-GENRS 293
+ G+ +A + ++ G Q + + P + G G++ G GP G
Sbjct: 1404 QGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGP 1463
Query: 294 MSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPG-----GPMDE----GP 344
M P G +G G G G G GE+G PG GP E GP
Sbjct: 1464 MGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGP 1523
Query: 345 DLDLGPPVDP 354
+GPP P
Sbjct: 1524 SGPIGPPGPP 1533
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 87.0 bits (214), Expect = 5e-17
Identities = 141/520 (27%), Positives = 178/520 (34%), Gaps = 85/520 (16%)
Query: 151 PQSSTGGYNQPSL--GYGQSNYSYPQVPGSYPMQP-VTAPPSYPPTSYSSTQPTSYDQSS 207
P GG+ P G + + PQ P +P T PP T PT
Sbjct: 2175 PPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGR-----GLTGPTG----- 2224
Query: 208 YSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQ--APSQYSQQSSSYGQQS 265
G P G G Q S G P Q G + AP + +
Sbjct: 2225 -----AVGLPGPPGPSGLVGPQGSPG------LPGQVGETGKPGAPGR---------DGA 2264
Query: 266 SFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR-GRGRGGFDRGGMSRGGRGGGRGGM 324
S + S GV G S G GP + GP G+ G +G GG G +
Sbjct: 2265 SGKDGDRGSPGVPG--SPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDL 2322
Query: 325 -GSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQ 383
G G +G PG ++G G P DP ED A +G FK
Sbjct: 2323 VGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKG-------------FKG 2369
Query: 384 CGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVS 443
V + G P G P + P A V F G+ ++
Sbjct: 2370 DPGVGVPGSPGPP----------GPPGVKGDLGLPGLPGAPGVVG-FPGQTGPRGEMG-- 2416
Query: 444 LARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG--GDRG-GFPPR 500
+P + RG P G+P PL GP GP G GP G G +G GD G G P
Sbjct: 2417 ----QPGPSGERGLAGPPGREGIPGPL--GPPGPPGSVGPPGASGLKGDKGDPGVGLP-- 2468
Query: 501 GPRGSRGNPS--GGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPP 558
GPRG RG P G + G P + + +G P
Sbjct: 2469 GPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGP 2528
Query: 559 PG-----GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFG 611
PG GD G GP G+ G +G D G PG G GD+G G G RG+
Sbjct: 2529 PGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQ 2588
Query: 612 GGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQER 651
G G PG P P + + G RG +G G M + ER
Sbjct: 2589 PGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGER 2628
Score = 82.8 bits (203), Expect = 9e-16
Identities = 127/465 (27%), Positives = 160/465 (34%), Gaps = 78/465 (16%)
Query: 197 STQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQ 256
+TQP Y + G+P G + G G T P G A ++
Sbjct: 1239 TTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAK--- 1295
Query: 257 QSSSYGQQSSFRQD-HPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRG 315
G++ D P S G G G PG S P RG D G RG
Sbjct: 1296 -----GERGFPGADGRPGSPGRAGNP-GTPGAPGLKGSPGLPGPRG------DPG--ERG 1341
Query: 316 GRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLD 375
RG +G G+ G+ G PG P +G GPP D GL +
Sbjct: 1342 PRGP-KGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKG 1400
Query: 376 DLADFFKQ--CGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGK 433
D D ++ G + G+P + G P PP K
Sbjct: 1401 DKGDRGERGPPGPGEGGIAPGEPGL-------PGLPGSPGPQGPVGPPGKKG-------- 1445
Query: 434 DFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG----- 488
+K GLP + G P GP GP G GP G G
Sbjct: 1446 -------------EKGDSEDGAPGLPGQPG----SPGEQGPRGPPGAIGPKGDRGFPGPL 1488
Query: 489 GRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKP 548
G G++G P GP GSRG P G + G P P G Q E + P
Sbjct: 1489 GEAGEKGERGPPGPAGSRGLPGVAGRPGAK-GPEGPPGP-TGRQG-----EKGEPGRPGD 1541
Query: 549 EGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRG-----GDRG--GFRG 601
+ P P G++G GP G RG G +RG PG + G G GDRG G G
Sbjct: 1542 PAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTG 1601
Query: 602 GRGMDRGGFGGGRRGGPG--GPPGPL----MEQMGGRRGGRGGPG 640
G G +G PG GPPGP+ + G +G G PG
Sbjct: 1602 RAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPG 1646
Score = 82.0 bits (201), Expect = 2e-15
Identities = 143/526 (27%), Positives = 179/526 (34%), Gaps = 101/526 (19%)
Query: 166 GQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQ--SSYSQQNTYGQPSSYGQQ 223
G S P +PG P P P PP + + ++ G P G +
Sbjct: 1448 GDSEDGAPGLPGQ-PGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSR 1506
Query: 224 SSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESG 283
G G + P P TG + G+ P+ G G++
Sbjct: 1507 GLPGVAGRPGAKGPEGPPGPTGRQGE--------KGEPGRPGDPAVVGPAVAGPKGEK-- 1556
Query: 284 GFSGPGENRSMSG------------PDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERG 331
G GP R +G P + G DRG + GR G G G GE+G
Sbjct: 1557 GDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKG 1616
Query: 332 GFNKPGGPMDEGP---------DLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFK 382
+PG P GP D GPP DP +GL + +
Sbjct: 1617 DPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGE---RGLRGAPGVRGPVGEKG 1673
Query: 383 QCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKV 442
G + R G P + PKGD P + V+ G
Sbjct: 1674 DQGDPGEDGRNGSP--------GSSGPKGDRGEPGPPGPPGR-LVDTGPG---------- 1714
Query: 443 SLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPG-----GPGGPMGRMGGRG--GDRG 495
AR+K RG PR +G P L G PG G GP GP G G RG G++G
Sbjct: 1715 --AREKGEPGD-RGQEGPRGPKG-DPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKG 1770
Query: 496 GFPPRGPRGSRG--------NPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPK 547
P G G G PSG +AGD PG + +
Sbjct: 1771 DRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGD-----PG-----------RDGLPGLR 1814
Query: 548 PEGFLPPPFPPPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGF-RGGRG 604
E LP P PPG G G G G+ G G + G PG R G GD G R GR
Sbjct: 1815 GEQGLPGPSGPPGLPGKPGEDGKPGLNGKNG---EPGDPGEDGRKGEKGDSGASGREGRD 1871
Query: 605 MDRGGFGGGRRGGPGGP---PGPLMEQMGGRRGGRGGPG-KMDKGE 646
+G G GP GP PGP+ G G GG G K D+GE
Sbjct: 1872 GPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGE 1917
Score = 80.5 bits (197), Expect = 5e-15
Identities = 138/494 (27%), Positives = 173/494 (35%), Gaps = 100/494 (20%)
Query: 204 DQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQ 263
DQ + G P S G + G+ G P TG ++ + + +
Sbjct: 1674 DQGDPGEDGRNGSPGSSGPKGDRGEPGPPG---PPGRLVDTGPGAREKGEPGDRGQEGPR 1730
Query: 264 QSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGG 323
P + G G E GF GP GP D G G G RG
Sbjct: 1731 GPKGDPGLPGAPGERGIE--GFRGP------PGPQG--------DPGVRGPAGEKGDRGP 1774
Query: 324 MGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQ 383
G G G KPG GP+ G DP D QGL L +
Sbjct: 1775 PGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGE 1834
Query: 384 CGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVS 443
G +N + G+P G P D E + + E DG + +
Sbjct: 1835 DGKPGLNGKNGEP----------GDPGEDGRKG-EKGDSGASGREGRDGPKGERGAPGI- 1882
Query: 444 LARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPG--GPGGPMGRMGGRGGDRGGFPPRG 501
L + PP GLP G PP +G PG PG GP G G G +G G P G
Sbjct: 1883 LGPQGPP------GLPGPVG----PPGQGFPGVPGGTGPKGDRGETGSKG--EQGLP--G 1928
Query: 502 PRGSRGNPSGGGNVQ---HRAG-----------DWQ------CPNPGCGNQNFAWRTECN 541
RG RG P NV AG W P P + + +
Sbjct: 1929 ERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVP---ERRRGPKGDSG 1985
Query: 542 QCKAPKPEGFL--------------PPPFPPPG---GDRGRGGPGGMRG--GRGGLMD-R 581
+ P EG + P P PPG G+RG GP G+ G G+ G+
Sbjct: 1986 EQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLP 2045
Query: 582 GGPGGMFRGGRGGDRG-----GFRGGRGMDRGGFGGGRRGGPGGPPGPLM---EQMGGRR 633
G GG+ GR G+RG G RG +G D G G GP GPPGP + E G
Sbjct: 2046 GRAGGVGEAGRPGERGERGEKGERGEQGRD-GPPGLPGTPGPPGPPGPKVSVDEPGPGLS 2104
Query: 634 GGRGGPG-KMDKGE 646
G +G PG K KGE
Sbjct: 2105 GEQGPPGLKGAKGE 2118
Score = 80.5 bits (197), Expect = 5e-15
Identities = 143/567 (25%), Positives = 194/567 (34%), Gaps = 112/567 (19%)
Query: 140 QDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQ 199
+DG K + S G + P G PQ P P PV P P T
Sbjct: 1852 EDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLP-GPVGPPGQGFPGVPGGTG 1910
Query: 200 PTSYDQSSYSQQNTYGQPSSYGQQSSYGQ-------------QSSYGQQPPTSYPPQTGS 246
P D+ + G P G + G ++S ++ ++ +GS
Sbjct: 1911 PKG-DRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGS 1969
Query: 247 YSQAPSQYSQQSSSYGQQSSFRQD----HPSSMGVYGQESG-GFSGP-----GENRSMSG 296
+ P + G+Q ++ P G+ G G GP GE R G
Sbjct: 1970 FLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGE-RGPPG 2028
Query: 297 PDNRGR--GRGGFD-----RGGMSRGGRGGGRGGMGSAGERGGFNK---PGGPMDEGPDL 346
P G+ G GG+ GR G RG G GERG + PG P GP
Sbjct: 2029 PSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPG 2088
Query: 347 DLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKET 406
GP V DE GL+ + G + G+P + +
Sbjct: 2089 PPGPKVSVDEPGP-------GLSG------------EQGPPGLKGAKGEPGSN----GDQ 2125
Query: 407 GKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGM 466
G PKGD V + DG + ++ KP + RG P G G
Sbjct: 2126 G-PKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGD 2184
Query: 467 PPP-----------------LRGGPGGPGGPG----GPMGRMGGRGGDRGGFPPRGPRGS 505
P P L+G PG G PG GP G +G G P GP G
Sbjct: 2185 PGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPG-------PPGPSGL 2237
Query: 506 RGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGR 565
G P G + + G + PG ++ A + ++ P P P P G +G
Sbjct: 2238 VG-PQGSPGLPGQVG--ETGKPGAPGRDGASGKDGDRGSPGVPGS---PGLPGPVGPKGE 2291
Query: 566 GGPGGMRGGR-----GGLMDRGGPGGMF-----RGGRGGDRG--GFRGGRGMDRGGFGGG 613
GP G G G ++G PGG+ G GDRG G RG +G G
Sbjct: 2292 PGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKG------EAG 2345
Query: 614 RRGGPGGPPGPLMEQMGGRRGGRGGPG 640
R G PG P + G +G +G PG
Sbjct: 2346 RAGEPGDPGEDGQKGAPGPKGFKGDPG 2372
Score = 79.7 bits (195), Expect = 8e-15
Identities = 79/239 (33%), Positives = 92/239 (38%), Gaps = 58/239 (24%)
Query: 455 RGGLPPREGR-GMP--PPLRGGPGGPG--------GPGGPMGRMG--------------G 489
R G P R G G P P L+G PG PG GP GP G G G
Sbjct: 1306 RPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPG 1365
Query: 490 RGGDRGGFPPRGPRGSRGNPSGGG----------NVQHRAGDWQCPNPGCGNQNFAWRTE 539
R GD G P GPRG G+P G + G+ P PG G
Sbjct: 1366 RKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGEPGL 1425
Query: 540 CNQCKAPKPEGFLPPP---------------FPPPGGDRGRGGPGGMRGGRGGLMDRGGP 584
+P P+G + PP P G G GP G G G DRG P
Sbjct: 1426 PGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFP 1485
Query: 585 GGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 641
G + G G+RG G G RG+ G G GP GPPGP GR+G +G PG+
Sbjct: 1486 GPLGEAGEKGERGPPGPAGSRGLP-GVAGRPGAKGPEGPPGPT-----GRQGEKGEPGR 1538
Score = 79.3 bits (194), Expect = 1e-14
Identities = 142/511 (27%), Positives = 177/511 (34%), Gaps = 109/511 (21%)
Query: 188 PSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSY 247
P PP S ++ + + + + G+ + G + G + S G P P + G
Sbjct: 1285 PQGPPGSATAKGERGFPGAD-GRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPR 1343
Query: 248 SQA--PSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRG 305
P Q G R+ P G G G PG P +G
Sbjct: 1344 GPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPR-GPLGDPGPRGPPGLPGTAMKGDK 1402
Query: 306 GFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYV 365
G DRG RG G G GG+ + GE G PG P +GP +GPP E D+
Sbjct: 1403 G-DRG--ERGPPGPGEGGI-APGEPGLPGLPGSPGPQGP---VGPPGKKGEKGDSE---- 1451
Query: 366 QGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKA 425
G P + G+P PP A
Sbjct: 1452 ---------------------------DGAPGL-------PGQPGSPGEQGPRGPPGA-- 1475
Query: 426 AVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPG--GPGGPGGP 483
K +G + A +K RG P RG+P + G PG GP GP GP
Sbjct: 1476 ----IGPKGDRGFPGPLGEAGEK----GERGPPGPAGSRGLPG-VAGRPGAKGPEGPPGP 1526
Query: 484 MGRMG-----GRGGDRGGFPPR--GPRGSRGN-----PSGGGNVQHRAGDWQCPNPGCGN 531
GR G GR GD P GP+G +G+ P G VQ G PG
Sbjct: 1527 TGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPG 1586
Query: 532 QNF--AWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRG--GRGGLM----DRGG 583
R P G PP GD GR GP G G GR G + D G
Sbjct: 1587 PKGDPGDRGPIGLTGRAGPPGDSGPPGEK--GDPGRPGPPGPVGPRGRDGEVGEKGDEGP 1644
Query: 584 PGGMFRGGRGGDRG-----GFRG--GRGMDRGGFG-GGRRGGPG-----------GPPGP 624
PG G+ G+RG G RG G D+G G GR G PG GPPGP
Sbjct: 1645 PGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGP 1704
Query: 625 LMEQMGGRRGGRGGPGKMDKGEHRQERRDRP 655
GR GPG +KGE ++ P
Sbjct: 1705 -----PGRLVDT-GPGAREKGEPGDRGQEGP 1729
Score = 79.3 bits (194), Expect = 1e-14
Identities = 114/387 (29%), Positives = 133/387 (34%), Gaps = 77/387 (19%)
Query: 289 GENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLD- 347
G+N P GR D G R GR G +G G+ G G PG P GP
Sbjct: 1842 GKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQG 1901
Query: 348 -------LGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHI 400
GP D E QGL L G+P
Sbjct: 1902 FPGVPGGTGPKGDRGETGSKGE---QGLPGERGL------------------RGEPGSVP 1940
Query: 401 YLDK--ETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGL 458
+D+ ET K A + VE +D + GS L V R+ P +S G
Sbjct: 1941 NVDRLLETAGIKASAL---------REIVETWD--ESSGSFLPVPERRRGPKGDSGEQGP 1989
Query: 459 PPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHR 518
P +EG P RG G G PG P G G G+RG P G G G P G
Sbjct: 1990 PGKEGPIGFPGERGLKGDRGDPG-PQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRA 2048
Query: 519 AGDWQCPNPGCGNQ--NFAWRTECNQCKAPKPEGFLPPPFPP------------------ 558
G + PG + R E + P G PP PP
Sbjct: 2049 GGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQG 2108
Query: 559 PGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGMDRGGFGGG 613
P G +G G G G +G DRG PG G G RG G G RGM G G
Sbjct: 2109 PPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGM-AGPEGKP 2167
Query: 614 RRGGPGGPPGPLMEQMGGRRGGRGGPG 640
GP GPPGP+ GG G PG
Sbjct: 2168 GLQGPRGPPGPV--------GGHGDPG 2186
Score = 70.1 bits (170), Expect = 6e-12
Identities = 105/377 (27%), Positives = 134/377 (35%), Gaps = 84/377 (22%)
Query: 316 GRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLD 375
G+ G RG MG G G G P EG LGPP P A ++G
Sbjct: 2407 GQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKG-------- 2458
Query: 376 DLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKA-AVEWFD--G 432
D D G+ G+P I E G+P + PP ++ E D
Sbjct: 2459 DKGD--PGVGLPGPRGERGEPGIR----GEDGRPGQEGPRGLTGPPGSRGERGEKGDVGS 2512
Query: 433 KDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMP------------------------- 467
+G K ++ P +G + R RG+
Sbjct: 2513 AGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKG 2572
Query: 468 ----PPLRG--GPGG-------PGGPGGPMGRMG-----GRGGDRGGFPPRGPRGSRGNP 509
P LRG GP G PG PG P G+ G G GD G PRG +G RG
Sbjct: 2573 SAGLPGLRGLLGPQGQPGAAGIPGDPGSP-GKDGVPGIRGEKGDVGFMGPRGLKGERGVK 2631
Query: 510 SGGGNVQHRAGDWQCPNPG----CGNQNFAWRTEC-NQCKAPKPEGFLPPPFPPPGGDRG 564
G + + PG G++ Q AP EG + P GDRG
Sbjct: 2632 GACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPK-----GDRG 2686
Query: 565 RGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGP 624
G G +G +G +RG PG GGF G G D G G G GP GP
Sbjct: 2687 FDGQPGPKGDQGEKGERGTPG----------IGGFPGPSGND-GSAGPPGPPGSVGPRGP 2735
Query: 625 LMEQMGGRRGGRGGPGK 641
E + G++G RG PG+
Sbjct: 2736 --EGLQGQKGERGPPGE 2750
Score = 64.3 bits (155), Expect = 3e-10
Identities = 68/190 (35%), Positives = 76/190 (40%), Gaps = 28/190 (14%)
Query: 460 PREGRGMPPP--LRGGPGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNV 515
P+ +G P LRG G PG PG P GR G G G G +G RG G G+
Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPGDPGLP-GRTGAPGPQGPPGSATAKGERGFPGADGRPGS- 1309
Query: 516 QHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGR 575
RAG NPG AP +G P P P GD G GP G +G
Sbjct: 1310 PGRAG-----NPGTPG-------------APGLKG--SPGLPGPRGDPGERGPRGPKGEP 1349
Query: 576 GGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGG 635
G G G GR GD G G RG G GP G PG M+ G RG
Sbjct: 1350 GAPGQVIGGEGPGLPGRKGDPGP--SGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGE 1407
Query: 636 RGGPGKMDKG 645
RG PG + G
Sbjct: 1408 RGPPGPGEGG 1417
Score = 61.6 bits (148), Expect = 2e-09
Identities = 112/447 (25%), Positives = 146/447 (32%), Gaps = 95/447 (21%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 274
GQP G++ G G P P GS + S G + P
Sbjct: 2416 GQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGA-----SGLKGDKGDPGVGLPGP 2470
Query: 275 MGVYGQES--GGFSGPGEN--RSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGG----MGS 326
G G+ G PG+ R ++GP RG ++G + G G +G +G
Sbjct: 2471 RGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERG--EKGDVGSAGLKGDKGDSAVILGP 2528
Query: 327 AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGV 386
G RG G G D D GP D + D + G S L L G
Sbjct: 2529 PGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQ 2588
Query: 387 VKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSK-LKVSLA 445
G P G P D K V + + +G + +K +
Sbjct: 2589 PGAAGIPGDP----------GSPGKDGVPGIRGE---KGDVGFMGPRGLKGERGVKGACG 2635
Query: 446 RKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG--GRGGDRGGFPPRGPR 503
+ G P R G G PG PG G P G+ G G GDRG GP+
Sbjct: 2636 LDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAP-GKEGLIGPKGDRGFDGQPGPK 2694
Query: 504 GSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDR 563
G +G G PG G FP P G+
Sbjct: 2695 GDQGEKGERGT------------PGIGG------------------------FPGPSGND 2718
Query: 564 GRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPG 623
G GP G PG + G RG + G +G +G +RG G G PG P
Sbjct: 2719 GSAGP------------PGPPGSV--GPRGPE--GLQGQKG-ERGPPGERVVGAPGVPGA 2761
Query: 624 PLMEQMGGRRGGRGGPG----KMDKGE 646
P G RG +G PG + +KGE
Sbjct: 2762 P------GERGEQGRPGPAGPRGEKGE 2782
Score = 50.4 bits (119), Expect = 5e-06
Identities = 38/101 (37%), Positives = 44/101 (43%), Gaps = 8/101 (7%)
Query: 546 PKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----GFR 600
P+PE P P P G +G G G+RG G D G PG G G G G R
Sbjct: 1242 PRPE---PCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGER 1298
Query: 601 GGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 641
G G D GR G PG P P ++ G G RG PG+
Sbjct: 1299 GFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGE 1339
>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
Length = 1745
Score = 86.7 bits (213), Expect = 6e-17
Identities = 132/477 (27%), Positives = 164/477 (34%), Gaps = 83/477 (17%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFR------ 268
G P G G Q G P YP G + ++ Q + F
Sbjct: 683 GHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDV 742
Query: 269 -----QDHPSSMGVYGQESG-GFSGPGENRSMSGPDNRGRGRGGFDRGGM-SRGGRGGGR 321
Q P + G G++ G G GP +G G+ GR G +
Sbjct: 743 GLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPK 802
Query: 322 GG------MGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLD 375
G +G GE+G K G P EG + GPP E A G V D
Sbjct: 803 GSIGFPGPLGPIGEKGKSGKTGQPGLEG---ERGPPGSRGERGQPGATGQPGPKGDVGQD 859
Query: 376 DLADFFKQCGVVKMNKRTG-----QPMIHIYLDKETGKP--KGDATVSYEDPPTAKAAVE 428
+ G+ + G P H D G P +G+ + P A V
Sbjct: 860 GAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVL 919
Query: 429 WFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGR-------GMPPPL--------RGG 473
GK + L PP GLP EGR G P PL RG
Sbjct: 920 GPQGKTGEVGPLG-ERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGF 978
Query: 474 PGGPGGPG--GPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGN 531
PG GGPG GP G G +G P GP G+ G+P G + G PG
Sbjct: 979 PGPKGGPGDPGPTGLKGDKG-------PPGPVGANGSPGERGPLGPAGG---IGLPG--- 1025
Query: 532 QNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGG 591
Q + P G P G+RG GP G G G L G PG G
Sbjct: 1026 ----------QSGSEGPVG--PAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSG 1073
Query: 592 RGGDRG-----GFRGGRGMDRGGFG-GGRRG--GPGGPPGPLMEQMGGRRGGRGGPG 640
GD+G G +G +G D+G G G+ G GP G PGP G +G RG PG
Sbjct: 1074 EEGDKGDVGAPGHKGSKG-DKGDAGPPGQPGIRGPAGHPGP--PGADGAQGRRGPPG 1127
Score = 85.9 bits (211), Expect = 1e-16
Identities = 139/539 (25%), Positives = 181/539 (33%), Gaps = 99/539 (18%)
Query: 147 ETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYP----PTSYSSTQPTS 202
E QP ++ G P GQ P +PG + + PP +P P +
Sbjct: 840 ERGQPGAT--GQPGPKGDVGQDGA--PGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRP 895
Query: 203 YDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY-----PPQTGSYSQAPSQYSQQ 257
+ GQ G G Q G+ P PP P ++
Sbjct: 896 GHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGRE 955
Query: 258 SSS--YGQQSSFRQDHPSSMGVYGQESGGFSGPGEN--RSMSGPD-----NRGRGRGG-- 306
+ G ++ P+ + + GG PG + GP N G G
Sbjct: 956 GAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPL 1015
Query: 307 FDRGGMSRGGRGGGRGGMGSAGERG--GFNKPGGPMDE----GPDLDLGPP--VDPD-ED 357
GG+ G+ G G +G AG++G G P GP + GP LGPP P E+
Sbjct: 1016 GPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEE 1075
Query: 358 SDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSY 417
D + G S K +K P G+P +
Sbjct: 1076 GDKGDVGAPGHKGS----------------KGDKGDAGP---------PGQPGIRGPAGH 1110
Query: 418 EDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGP 477
PP A A QG + L +K + +RG + G PP L+G PG P
Sbjct: 1111 PGPPGADGA---------QGRRGPPGLFGQKGD-DGVRGFV----GVIGPPGLQGLPGPP 1156
Query: 478 GGPG--GPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQN 533
G G G +G MG G G RG P+GP GS G P G V PG +
Sbjct: 1157 GEKGEVGDVGSMGPHGAPGPRG---PQGPTGSEGTPGLPGGVGQ---------PGAVGE- 1203
Query: 534 FAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRG 593
+ E P P G P P P GD G G G G G +G PG G
Sbjct: 1204 ---KGERGDAGDPGPPG--APGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSV 1258
Query: 594 GDRG-----GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEH 647
G G G G G+ G +G PG GP G G G PGK H
Sbjct: 1259 GPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGH 1317
Score = 79.3 bits (194), Expect = 1e-14
Identities = 104/385 (27%), Positives = 134/385 (34%), Gaps = 102/385 (26%)
Query: 272 PSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERG 331
P G+ G+E G GP R + GP G R G G G G G G+RG
Sbjct: 496 PGHPGLKGEE--GAEGPQGPRGLQGPHGPPGRVGKMGRPGAD--GARGLPGDTGPKGDRG 551
Query: 332 GFNKPGGPMDEGPDLD---LGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVK 388
PG P ++G D +G P P ED + A G
Sbjct: 552 FDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTG------------------ 593
Query: 389 MNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK 448
+ G+P P+G PT + V DG G+K V +
Sbjct: 594 ---QAGEP-----------GPRGLLGPRGSPGPTGRPGVTGIDGAP--GAKGNVGPPGEP 637
Query: 449 PPM----NSMRGGLPPREGRGMPPPLRGGPGGPGGPG-----GPMGRMGGRGGDRGGFPP 499
P N GLP +G P +G PG PG PG GP+G G G P
Sbjct: 638 GPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEG-------P 690
Query: 500 RGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPP 559
G +G++G P G PP +P P
Sbjct: 691 TGEKGAQGPPGSAG---------------------------------------PPGYPGP 711
Query: 560 GGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMD--RGGFGGGRR 615
G +G G G++G +G + G PG G GD+G G G RG D G G +
Sbjct: 712 RGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQ 771
Query: 616 GGPGGPPGPLMEQMGGRRGGRGGPG 640
G GPPG E+ G+ G G PG
Sbjct: 772 AGEEGPPGSAGEK--GKLGVPGLPG 794
Score = 73.6 bits (179), Expect = 6e-13
Identities = 122/465 (26%), Positives = 155/465 (33%), Gaps = 115/465 (24%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 274
G+P GQQ ++G Q G Q P + G +P
Sbjct: 635 GEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGP----------------------PGNPGI 672
Query: 275 MGVYGQESG----GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGER 330
G+ G + G GP + GP G G+ G G G RG G GE+
Sbjct: 673 PGLPGSDGPLGHPGHEGPTGEKGAQGPPGSA-GPPGYP-GPRGVKGTSGNRGLQGEKGEK 730
Query: 331 GGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMN 390
G PG D G D G P P ++ +G Q G
Sbjct: 731 GEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKG---------------QAGQAGEE 775
Query: 391 KRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPP 450
G E GK Y P K ++ + G K K
Sbjct: 776 GPPGSA-------GEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGK--------- 819
Query: 451 MNSMRGGLPPREGRGMPPPLRGGPGGPG-----GPGGPMGRMGGRG--GDRG-------- 495
S + G P EG PP RG G PG GP G +G+ G G G++G
Sbjct: 820 --SGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPP 877
Query: 496 GFP-PRGPRGSRGNPSGGGNVQHRA-----GDWQCPNPG--CGNQNFAWRTECNQCKAPK 547
GFP P+GP G +G G+ R G P P G Q
Sbjct: 878 GFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVG-------- 929
Query: 548 PEGFLPPPFPP-PGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMD 606
P G PP PP P G++G G G G +G L G PG + + G G RG
Sbjct: 930 PLGERGPPGPPGPPGEQGLPGLEGREGAKGEL---GPPGPLGKEGPAGLRGF-------- 978
Query: 607 RGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQER 651
G +GGPG P GP G +G +G PG + ER
Sbjct: 979 -----PGPKGGPGDP-GPT-----GLKGDKGPPGPVGANGSPGER 1012
Score = 72.0 bits (175), Expect = 2e-12
Identities = 141/545 (25%), Positives = 175/545 (32%), Gaps = 110/545 (20%)
Query: 136 PTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVP-GSYPMQPVTAPPSYPPTS 194
P P N P GG P GQS P P G + PP PT
Sbjct: 999 PPGPVGANGSPGERGPLGPAGGIGLP----GQSGSEGPVGPAGKKGSRGERGPPG--PTG 1052
Query: 195 YSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQY 254
G+ G + G + S G + P Q G + P+ +
Sbjct: 1053 KDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGI--RGPAGH 1110
Query: 255 SQQSSSYGQQSSFRQDHPSSMGVYGQESG----GFSGPGENRSMSGPDNRGRGRGGFDRG 310
+ G Q R+ P G G + G GP + + GP +G G D G
Sbjct: 1111 PGPPGADGAQG--RRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGE-KGEVG-DVG 1166
Query: 311 GMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLND 370
M G G RG G G G PGG G + G D + A + G
Sbjct: 1167 SMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKG 1226
Query: 371 SVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWF 430
+ KGD+ S P K
Sbjct: 1227 DIG-----------------------------------EKGDSGPSGAAGPPGKKGPPGE 1251
Query: 431 DGKDFQGSKLKVSLARKK-PPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG-------- 481
DG +GS L PP + G+ G P GGPG PG G
Sbjct: 1252 DGA--KGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPP 1309
Query: 482 ---GPMGRMG--GRGGDRG--------GFPPR-GPRGSRGNPSGGGNVQHRAGDWQCPNP 527
GP G MG GR G++G G P R GP G+RG P G R P
Sbjct: 1310 GKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEP 1369
Query: 528 GCGNQNFAWRTECNQCKAPKPEGFLPPPFP-PPGGDRGRGGPGGMRGGRG--GLMDRGGP 584
G AP G + PP P P G G G G +G +G GL+ GP
Sbjct: 1370 GL-------------LGAP---GQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGP 1413
Query: 585 GGMFRGGRGGDRG--GFRGGRGM-----DRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRG 637
G G GD+G G +G G G G GP G GPL G++G +G
Sbjct: 1414 PG--EAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPL-----GQKGSKG 1466
Query: 638 GPGKM 642
PG M
Sbjct: 1467 SPGSM 1471
Score = 67.8 bits (164), Expect = 3e-11
Identities = 102/360 (28%), Positives = 125/360 (34%), Gaps = 68/360 (18%)
Query: 320 GRGGMGSAGERGGFNK-------PGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSV 372
G G G+ GE K PG P +G GPP P D GL
Sbjct: 371 GAGEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIP 430
Query: 373 TLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDG 432
+D + G P I + P A S++ PP + F
Sbjct: 431 GIDGIR---------------GPPGTVIMM------PFQFAGGSFKGPPVS------FQQ 463
Query: 433 KDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRG--------GPGGPGGPGGPM 484
Q + L+ K PP G P G P L+G GP G GP GP
Sbjct: 464 AQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPP 523
Query: 485 GRMG--GRGGDRG--GFP----PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAW 536
GR+G GR G G G P P+G RG G P G R PG ++
Sbjct: 524 GRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGER 583
Query: 537 RTE-----CNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGG 591
E Q P P G L P P G GR G G+ G G + G PG G
Sbjct: 584 GAEGPPGPTGQAGEPGPRGLLGPRGSP--GPTGRPGVTGIDGAPGAKGNVGPPGEPGPPG 641
Query: 592 RGGDRG--GFRGGRGMDRGGFGGGRRGGPG-----GPPGPL----MEQMGGRRGGRGGPG 640
+ G+ G G G +G+ G G PG G GPL E G +G +G PG
Sbjct: 642 QQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPG 701
Score = 64.7 bits (156), Expect = 3e-10
Identities = 73/224 (32%), Positives = 88/224 (39%), Gaps = 39/224 (17%)
Query: 449 PPMNSMRGGLPPREG-RGMPPPL-----RGGPGGPGGPG-----GPMGRMG-----GRGG 492
PP + G P +G RG+P RG G PG PG G G +G G G
Sbjct: 522 PPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDG 581
Query: 493 DRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFL 552
+RG P GP G G P G + R PG + AP +G +
Sbjct: 582 ERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGID----------GAPGAKGNV 631
Query: 553 PPPFP--PPG-----GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGR 603
PP PPG G +G GP G+ G G G PG G G G G G
Sbjct: 632 GPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPT 691
Query: 604 GMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPG-KMDKGE 646
G ++G G GP G PGP + G G RG G K +KGE
Sbjct: 692 G-EKGAQGPPGSAGPPGYPGP--RGVKGTSGNRGLQGEKGEKGE 732
Score = 64.3 bits (155), Expect = 3e-10
Identities = 113/436 (25%), Positives = 139/436 (31%), Gaps = 89/436 (20%)
Query: 211 QNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQD 270
Q G P G+ G +G P TGS + G Q
Sbjct: 1150 QGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGS-----------EGTPGLPGGVGQ- 1197
Query: 271 HPSSMGVYGQES-GGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGE 329
P ++G G+ G GP + GP +G D G G G +G G G
Sbjct: 1198 -PGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKG--DSGPSGAAGPPGKKGPPGEDGA 1254
Query: 330 RGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSV-TLDDLADFFKQCGVVK 388
+G G P D LGPP DP V G++ S D D
Sbjct: 1255 KGSVGPTGLPGD------LGPPGDPG---------VSGIDGSPGEKGDPGD--------- 1290
Query: 389 MNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK 448
G P G P PP + + +G K A+ +
Sbjct: 1291 ----VGGP----------GPPGASGEPGAPGPPGKRGPSGHMGREGREGEKG----AKGE 1332
Query: 449 PPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG-----GRGGDRGGFPPRGPR 503
P + G P RG PP R GP G G GP+G G G+ G G P G
Sbjct: 1333 PGPDGPPGRTGPMGARG--PPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLP 1390
Query: 504 GSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDR 563
G +G+ G H PG + Q P P+G P P P G
Sbjct: 1391 GLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQ-GPPGPKG--DPGPPGPIGSL 1447
Query: 564 GRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPG 623
G GP G+ G G +G PG M G GD G GP GPPG
Sbjct: 1448 GHPGPPGVAGPLGQKGSKGSPGSM---GPRGDTG-----------------PAGPPGPPG 1487
Query: 624 PLMEQMGGRRGGRGGP 639
E G RR R P
Sbjct: 1488 APAELHGLRRRRRFVP 1503
Score = 40.0 bits (92), Expect = 0.007
Identities = 61/205 (29%), Positives = 77/205 (37%), Gaps = 78/205 (38%)
Query: 497 FPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPF 556
FP G +G++G P+ V + ++ P PG AP P+G + P
Sbjct: 369 FPGAGEKGAKGEPA----VIEKGQQFEGP-PG----------------APGPQGVVGPSG 407
Query: 557 P--PPG--GDRGRGGPGGMRGGRGGLMDRGGP-----------GGMFRG----------- 590
P PPG GD G GP G+ G G RG P GG F+G
Sbjct: 408 PPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQ 467
Query: 591 --------------------GRGGDRG--GFRGGRGMDRGGFGGGRRG--GPGGPPGPLM 626
GR G G G G +G + G RG GP GPPG +
Sbjct: 468 AVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPG-RV 526
Query: 627 EQMG--GRRGGRGGPG----KMDKG 645
+MG G G RG PG K D+G
Sbjct: 527 GKMGRPGADGARGLPGDTGPKGDRG 551
>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
Length = 1669
Score = 83.6 bits (205), Expect = 5e-16
Identities = 152/563 (26%), Positives = 194/563 (34%), Gaps = 92/563 (16%)
Query: 122 PAYPAY-GQQPAATAPTRPQDGNKPTETSQPQS-STGGYNQPSLGYGQSNYSYPQVPGSY 179
P +P G A +P R P P S G P G G PGS
Sbjct: 546 PGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVG--------FPGSR 597
Query: 180 PMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTS 239
PP Y P + G P G G + G+ P
Sbjct: 598 GDTGPPGPPGYGPAG------------PIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLP 645
Query: 240 YPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSG-PD 298
PP +P Q + R P G GQ GF GP + + G P
Sbjct: 646 GPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPG 705
Query: 299 NRGR----GRGGFDRGGMSRGGRGG-GRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVD 353
+ G GR GF+ + G +G G G+G G +G PG P G +G P
Sbjct: 706 DMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGV 765
Query: 354 PDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDA 413
P E +QG+ L GV + G P G P G
Sbjct: 766 PGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGI----GPP-------GARGPPGGQG 814
Query: 414 TVSYEDPPTAKA--AVEWFDGKDFQGSKLKVSLARKKPPMNSMRG--GLPPREGR-GMP- 467
PP K F G D G K A+ P + G GLP ++G G+P
Sbjct: 815 PPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKG-AQGLPGITGQSGLPGLPGQQGAPGIPG 873
Query: 468 -------PPLRGGPGGPGGPGGPMGRMG--GRGGDRGGFPPRGPRGSRGNPSGGGNVQHR 518
+ G PG PG P GP+G G G GD GFP G G RG+P G+
Sbjct: 874 FPGSKGEMGVMGTPGQPGSP-GPVGAPGLPGEKGDH-GFP--GSSGPRGDPGLKGD---- 925
Query: 519 AGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGL 578
GD P G + + K K + G++G+ GP G +G RG
Sbjct: 926 KGDVGLP----GKPGSMDKVDMGSMKGQKGD----------QGEKGQIGPIGEKGSRG-- 969
Query: 579 MDRGGPGGMFRGGRGGDRG--GFRGGRGMD----RGGFGG--GRRGGPGGPPGPLMEQMG 630
D G PG + G+ G G G +G G+ G G G GG G P P + +
Sbjct: 970 -DPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVP 1028
Query: 631 GRRGGRGGPG----KMDKGEHRQ 649
G G +G PG K KGE Q
Sbjct: 1029 GIPGPQGSPGLPGDKGAKGEKGQ 1051
Score = 72.0 bits (175), Expect = 2e-12
Identities = 137/553 (24%), Positives = 181/553 (32%), Gaps = 104/553 (18%)
Query: 155 TGGYNQPSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTY 214
TG P L Q P PGS V P P + P ++ +
Sbjct: 854 TGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAP-----GLPGEKGDH 908
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAP-SQYSQQSSSYGQQSSF------ 267
G P S G + G + G P + GS + Q G++
Sbjct: 909 GFPGSSGPRGDPGLKGDKGD---VGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEK 965
Query: 268 -RQDHPSSMGVYGQESG----GFSGPGENRSMSG-PDNRGRGRGGFDRGGMSRGGRGGGR 321
+ P + GV G++ G GP + +SG P G GGM G G +
Sbjct: 966 GSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEK 1025
Query: 322 GGMGSAGERGGFNKPGGPMDEGPDLDLGPPV--------------------DPDEDSDNS 361
G G G +G PG +G GPP P E +
Sbjct: 1026 GVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKG 1085
Query: 362 AIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPP 421
+I + G+ S L G + G + LD G KG+A + P
Sbjct: 1086 SIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLP-GLDGIPGV-KGEAGLPGTPGP 1143
Query: 422 TAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMP--PPLRGGPGGPGG 479
T A + G D + S K P GLP GRG P P +G G G
Sbjct: 1144 TGPAGQKGEPGSD----GIPGSAGEKGEP------GLP---GRGFPGFPGAKGDKGSKGE 1190
Query: 480 PGGPMGRMGGRG-----GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNF 534
G P G G G G++G P GP+G G P G+ + P G
Sbjct: 1191 VGFP-GLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGL 1249
Query: 535 AWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGG 594
P P G PP P G +G G G G G +G PG G GG
Sbjct: 1250 -----------PGPMG--PPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGG 1296
Query: 595 DRG--------------GFRGGRGM-----------DRGGFGGGRRGGPGGPPGP--LME 627
G GF+G +G+ D+G G GP GPPGP +++
Sbjct: 1297 SPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIK 1356
Query: 628 QMGGRRGGRGGPG 640
G G G PG
Sbjct: 1357 GEPGLPGPEGPPG 1369
Score = 69.7 bits (169), Expect = 8e-12
Identities = 135/489 (27%), Positives = 166/489 (33%), Gaps = 80/489 (16%)
Query: 211 QNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQS--SFR 268
Q G+P G S G G PP + P G Q P S G++ F
Sbjct: 778 QGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGG---QGPPGLSGPPGIKGEKGFPGFP 834
Query: 269 Q-DHPSSMGVYGQESGGFSGPGENRSMSG-PDNRGR-GRGGFDRGGMSRGGRGGGRGGMG 325
D P G G + G G + G P +G G GF G G G G G
Sbjct: 835 GLDMPGPKGDKGAQ--GLPGITGQSGLPGLPGQQGAPGIPGFP-GSKGEMGVMGTPGQPG 891
Query: 326 SAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADF----- 380
S G G PG D G GP DP D + + G S+ D+
Sbjct: 892 SPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKG 951
Query: 381 ----FKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQ 436
Q G + G P G P D P K
Sbjct: 952 DQGEKGQIGPIGEKGSRGDP-------GTPGVPGKDGQAGQPGQPGPKG------DPGIS 998
Query: 437 GSKLKVSLARKKPPMNSMRGGLPPREG-RGMP--PPLRGGPGGPG--------GPGGPMG 485
G+ L K + M GLP G +G+P P +G PG PG G GP G
Sbjct: 999 GTPGAPGLPGPKGSVGGM--GLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPG 1056
Query: 486 ----RMGGRGGDRG--GFP----PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGC----GN 531
+ G GD+G GFP +G +GS G P G+ + PG G
Sbjct: 1057 IGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGE 1116
Query: 532 QNFAWRTECNQCKAPKPEGFLP--PPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFR 589
+ + K E LP P P G +G G G+ G G + G PG F
Sbjct: 1117 KGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFP 1176
Query: 590 G--GRGGDRG-----GFRGGRG-------MDRGGFGG--GRRGGPG--GPPGPLMEQMGG 631
G G GD+G GF G G GF G G +G PG G PG E G
Sbjct: 1177 GFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKG 1236
Query: 632 RRGGRGGPG 640
RG +G PG
Sbjct: 1237 DRGPQGQPG 1245
Score = 67.8 bits (164), Expect = 3e-11
Identities = 133/497 (26%), Positives = 171/497 (34%), Gaps = 87/497 (17%)
Query: 186 APPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYP-PQT 244
A P PP T P ++ G P G+ G GQ P P P
Sbjct: 325 AGPPGPPGIVIGTGPLG----EKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQ 380
Query: 245 GSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGR 304
P + ++ +S PS G PG+ +G G
Sbjct: 381 AGAPGFPGERGEKGDRGFPGTSL--PGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGP 438
Query: 305 GGFDRGGMSRGGRGGGRGGMGSAGERG---------GFNKPGGPMDEGPDLDLGPPVDPD 355
G D+G G+ G G +G G++G G+ P GP +GP ++G P P
Sbjct: 439 PG-DQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGP--QGPPGEIGFPGQPG 495
Query: 356 EDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATV 415
D +GL + + G++ G+P Y D KGD
Sbjct: 496 AKGD------RGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPG-EFYFDLRLKGDKGDPGF 548
Query: 416 SYEDPPTAKAAVEWFDGKD-FQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGP 474
+ T +A DG G K P ++G P G G P RG
Sbjct: 549 PGQPGMTGRAGSPGRDGHPGLPGPK-------GSPGSVGLKGERGPPGGVGFPGS-RGDT 600
Query: 475 GGPGGPG-GPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQN 533
G PG PG GP G +G +G + GFP G GS G P G P PG
Sbjct: 601 GPPGPPGYGPAGPIGDKG--QAGFP--GGPGSPGLPGPKGEPGKIV-----PLPG----- 646
Query: 534 FAWRTECNQCKAPKPEGFLP--PPFPPPGGDRGRGGPGGMRG--------GRGGLMDRGG 583
P EG LP P FP P GDRG G G G G+ G+ G
Sbjct: 647 -----------PPGAEG-LPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGP 694
Query: 584 PGGMFRGGRGGDRG-----GFRGGRGMDRGGFGGGRRGGPG-GPPG-------PLMEQMG 630
PG G GD G G G G+ G++G PG G PG P +
Sbjct: 695 PGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTP 754
Query: 631 GRRGGRGGPGKMDKGEH 647
G +G G PG GEH
Sbjct: 755 GEKGSIGVPGV--PGEH 769
Score = 67.0 bits (162), Expect = 5e-11
Identities = 75/218 (34%), Positives = 90/218 (41%), Gaps = 33/218 (15%)
Query: 457 GLPPREGRGMPPPLRGGPGGPG--------GPGGPMGRMG--GRGGDRGGFPPRGPRGSR 506
GLP +G PP G PG PG GP GP G G G G+RG P G G
Sbjct: 85 GLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFA 144
Query: 507 GNPSGGG--NVQHRAGDWQCPNPGC---GNQNFAWRTECNQCKAPKPEGF--LPPPFPPP 559
GNP G ++ G+ PG G + F P P G L P PP
Sbjct: 145 GNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFP-----GIPGTPGPPGLPGLQGPVGPP 199
Query: 560 G--GDRGRGGPGGMRGGRG--GLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFG---- 611
G G G GP G G +G GL +G G G G G + ++G F
Sbjct: 200 GFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGE 259
Query: 612 GGRRGGPG--GPPGPLMEQMGGRRGGRGGPGK-MDKGE 646
G++G PG G PG + G+ G RG PGK DKGE
Sbjct: 260 KGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGE 297
Score = 64.7 bits (156), Expect = 3e-10
Identities = 129/491 (26%), Positives = 165/491 (33%), Gaps = 109/491 (22%)
Query: 213 TYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQS-SFRQDH 271
T G P G Q G G P P G Q + G Q S
Sbjct: 183 TPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGV 242
Query: 272 PSSMGVYGQESGGFSGPGENRSMSGPDNRG------RGRGGFDRGGMSRGGRGGGRGGMG 325
P V QE G F+ GE P +G +G G G + G+ G +G G
Sbjct: 243 PGQAQV--QEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPG-KPGPRGKPGKDGDKGEKG 299
Query: 326 SAGERGGFNKPG-----GPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADF 380
S G G PG GP +G + GPP P + +G
Sbjct: 300 SPGFPGEPGYPGLIGRQGP--QGEKGEAGPPGPPGIVIGTGPLGEKG------------- 344
Query: 381 FKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYED-----PPTAKAAVEWFDGKDF 435
+ G G+P PKG + + P +A F G+
Sbjct: 345 --ERGYPGTPGPRGEP-----------GPKGFPGLPGQPGPPGLPVPGQAGAPGFPGE-- 389
Query: 436 QGSKLKVSLARKKPPMNSMRGGLPPREG-----------------RGMPPPLRGGPGGPG 478
+G K P S R GLP G + PP +G PG PG
Sbjct: 390 RGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPG 449
Query: 479 GPG--GPMGRMGGRG---------GDRGGFPPRGPRGSRGNP-----SGGGNVQHRAGDW 522
PG G +G G +G G RG P+GP G G P G + R G
Sbjct: 450 QPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVA 509
Query: 523 QCP----------NPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMR 572
P PG + + + + K K + P FP G GR G G
Sbjct: 510 GVPGPQGTPGLIGQPGAKGEPGEFYFDL-RLKGDKGD----PGFPGQPGMTGRAGSPGRD 564
Query: 573 GGRGGLMDRGGPGGM-FRGGRGGDRG-GFRGGRGMDRGGFGGGRRGGPG-GPPGPLMEQM 629
G G +G PG + +G RG G GF G RG G G PG GP GP+ ++
Sbjct: 565 GHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSRG------DTGPPGPPGYGPAGPIGDK- 617
Query: 630 GGRRGGRGGPG 640
G+ G GGPG
Sbjct: 618 -GQAGFPGGPG 627
Score = 62.0 bits (149), Expect = 2e-09
Identities = 127/468 (27%), Positives = 157/468 (33%), Gaps = 73/468 (15%)
Query: 221 GQQSSYGQQSSYGQQPPTSYPPQTGSY-SQAPSQYSQQSSSYGQQSSFRQDHPSSM-GVY 278
G Q G Q GQ+ T P G+ ++ P S + G QD P G+
Sbjct: 64 GMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIP 123
Query: 279 G-----QESGGFSGPGENRSMSGPDNRG----RGRGGFDRGGMSRGGRGGGRGGMGSAGE 329
G E G PG P G +G G G + G RG G G
Sbjct: 124 GCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGT 183
Query: 330 RGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKM 389
G PG GP GPP P GL+ D D GV
Sbjct: 184 PGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGD----QGVSGP 239
Query: 390 NKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKP 449
GQ + + KGD E + + G +G K R KP
Sbjct: 240 PGVPGQAQV---------QEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPG-PRGKP 289
Query: 450 PMNSMRG-----------GLPPREGRGMPPPLRGGPGGPGGPG-----GPMGRMGGRGGD 493
+ +G G P GR P +G G PG PG GP+G G RG
Sbjct: 290 GKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERG-- 347
Query: 494 RGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPG-CGNQNFAWRTECNQCKAPKPEGFL 552
G P GPRG G P G + + G P PG G F + GF
Sbjct: 348 YPGTP--GPRGEPG-PKGFPGLPGQPGPPGLPVPGQAGAPGFP-----GERGEKGDRGFP 399
Query: 553 PPPFPPPGGDRGRGGPGGMRGGRG------GLMD--RGGPGGMFRGGRGGDRG-----GF 599
P P G G GP G G G G+++ G PG G G G G
Sbjct: 400 GTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGE 459
Query: 600 RGGRG-----MDRGGFGGGRRGGPGGPPGPL-MEQMGGRRGGRGGPGK 641
+G +G D G+ G GP GPPG + G +G RG PG+
Sbjct: 460 KGQKGESCLICDIDGYRG--PPGPQGPPGEIGFPGQPGAKGDRGLPGR 505
Score = 58.9 bits (141), Expect = 1e-08
Identities = 70/206 (33%), Positives = 87/206 (42%), Gaps = 35/206 (16%)
Query: 457 GLPPREGRGMPPPLRG-----GPGGPGGPGGPMGRMG--GRGGDRGGFPPRGPRGSRGNP 509
G+ ++G P L+G G GP GP GP G+ G G G G RGP G+ G P
Sbjct: 43 GVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYP 102
Query: 510 SGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPK-PEGFLPPPFPPPGGDRGRGGP 568
G D PG CN K + P G PP P G+ G G
Sbjct: 103 GNPGLPGIPGQDGPPGPPGIPG--------CNGTKGERGPLG--PPGLPGFAGNPGPPGL 152
Query: 569 GGMRGGRGGLMDRGGPGGMFRGGRG-----GDRG--GFRGGRG-MDRGGFGGGRRGGPGG 620
GM+G G ++ PG + +G RG G G G G +G + GF G GP G
Sbjct: 153 PGMKGDPGEILGH-VPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTG--PPGPPG 209
Query: 621 PPGPLME--QMG----GRRGGRGGPG 640
PPGP E QMG G +G +G G
Sbjct: 210 PPGPPGEKGQMGLSFQGPKGDKGDQG 235
Score = 43.1 bits (100), Expect = 8e-04
Identities = 91/356 (25%), Positives = 108/356 (30%), Gaps = 78/356 (21%)
Query: 272 PSSMGVYGQ--ESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRG--------GGR 321
P G GQ E G PG P GRG GF +G +G G
Sbjct: 1141 PGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSP 1200
Query: 322 GGMGSAGERGGFNKPG-----------GPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLND 370
G GS GE+G PG G EGP D GP P + GL
Sbjct: 1201 GIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLP- 1259
Query: 371 SVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWF 430
G+ + G P G P + P +
Sbjct: 1260 --------------GIDGVKGDKGNP----------GWPGAPGVPGPKGDPGFQGMPGIG 1295
Query: 431 DGKDFQGSKLKVSLARKKPPMNSMRG--GLPPREGRGMPPPLRGGPG-----GPGGPGGP 483
GSK + P + +G GLP +G +G PG GP GP GP
Sbjct: 1296 GSPGITGSKGDMG----PPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGP 1351
Query: 484 MGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQC 543
+ G G G P G +G +G P G Q G P P
Sbjct: 1352 YDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQ-QGVTGLVGIPGP---------------- 1394
Query: 544 KAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGF 599
P GF P G+ G GP G RG G G PG M G GF
Sbjct: 1395 --PGIPGF--DGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTPSVDHGF 1446
Score = 42.0 bits (97), Expect = 0.002
Identities = 81/323 (25%), Positives = 99/323 (30%), Gaps = 49/323 (15%)
Query: 188 PSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSY 247
P P + D+ S + G S G S G+Q G P P GS
Sbjct: 1168 PGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSP 1227
Query: 248 SQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGF 307
A GQ G GP + G D G G
Sbjct: 1228 GHATEGPKGDRGPQGQPGL----------------PGLPGPMGPPGLPGID----GVKG- 1266
Query: 308 DRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQG 367
D+G G G G G G +G G P G D+GPP P +QG
Sbjct: 1267 DKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQG 1326
Query: 368 LNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAV 427
+ + G + G P + + E G P E PP K
Sbjct: 1327 IKGDQGDQGVP------GAKGLPGPPGPPGPYDIIKGEPGLP------GPEGPPGLKGLQ 1374
Query: 428 EWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRM 487
K QG V + PP G+P +G P + G GP GP GP G
Sbjct: 1375 GLPGPKGQQGVTGLVGI--PGPP------GIPGFDG----APGQKGEMGPAGPTGPRGFP 1422
Query: 488 GGRGGDRGGFPPRGPRGSRGNPS 510
G G D G P G G G PS
Sbjct: 1423 GPPGPD--GLP--GSMGPPGTPS 1441
Score = 36.2 bits (82), Expect = 0.098
Identities = 58/257 (22%), Positives = 75/257 (29%), Gaps = 34/257 (13%)
Query: 122 PAYPAYGQQPAATAPTRPQD-----GNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVP 176
P P + P PQ G+ T P+ G QP L P +P
Sbjct: 1200 PGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLP 1259
Query: 177 GSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQP 236
G ++ P +P D G P G + G G Q
Sbjct: 1260 GIDGVKGDKGNPGWPGAP--GVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQG 1317
Query: 237 PTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESG--GFSGPGENRSM 294
P P G Q + P + E G G GP + +
Sbjct: 1318 PKGLPGLQG----IKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGL 1373
Query: 295 SG-PDNRGR-------------GRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPM 340
G P +G+ G GFD G G +G MG AG G PG P
Sbjct: 1374 QGLPGPKGQQGVTGLVGIPGPPGIPGFD-------GAPGQKGEMGPAGPTGPRGFPGPPG 1426
Query: 341 DEGPDLDLGPPVDPDED 357
+G +GPP P D
Sbjct: 1427 PDGLPGSMGPPGTPSVD 1443
>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
sapiens]
Length = 940
Score = 83.2 bits (204), Expect = 7e-16
Identities = 81/215 (37%), Positives = 83/215 (38%), Gaps = 41/215 (19%)
Query: 465 GMPPPLRG------GPGGP-------GGPG---GPMGR-MGGRGGDRGGFPPRGPRGSRG 507
G PPP RG GPG P GGPG GP R GGRGG+ PP RG+RG
Sbjct: 668 GPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARG 727
Query: 508 NPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRG- 566
SGGG R G PG G P PGG G G
Sbjct: 728 GRSGGGPPNGRGG------PGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGH 781
Query: 567 ----GPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRR--GGPGG 620
GPGG GG GG GPGG GG G R G GM G GGG R GPGG
Sbjct: 782 RPHEGPGGSMGGGGGHRPHEGPGGGISGG-SGHRPHEGPGGGM---GAGGGHRPHEGPGG 837
Query: 621 PPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRP 655
MGG G R G G H D P
Sbjct: 838 -------SMGGSGGHRPHEGPGHGGPHGHRPHDVP 865
Score = 72.0 bits (175), Expect = 2e-12
Identities = 71/206 (34%), Positives = 74/206 (35%), Gaps = 64/206 (31%)
Query: 467 PPPLRGG--PGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQC 524
P P+ G PGGPGGP G G GG P GP G G P G
Sbjct: 622 PGPIANGFPPGGPGGPKGMQHFPPGPGG-----PMPGPHGGPGGPVG------------- 663
Query: 525 PNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGG-MRGG--RGGLMDR 581
P+ L PP PP GGD GPG MRGG RGG
Sbjct: 664 ---------------------PR---LLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPG 699
Query: 582 GGPGGMFRGGRGGDR-----GGFRGGRGMDRGGFGGGRRGGPGG------------PPGP 624
GP RGGRGG+ FRG RG GG RGGPGG PG
Sbjct: 700 PGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGG 759
Query: 625 LMEQMGGRRGGRGGPGKMDKGEHRQE 650
M G R G G M G E
Sbjct: 760 GMGNSSGHRPHEGPGGGMGSGHRPHE 785
Score = 59.7 bits (143), Expect = 8e-09
Identities = 82/225 (36%), Positives = 90/225 (40%), Gaps = 60/225 (26%)
Query: 472 GGPGG-PGGPGGPM------GRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQH-RAGDWQ 523
GG GG P G GG MG G +G P+GP G GG NVQ
Sbjct: 540 GGSGGSPDGAGGSKLPPVLANLMGSMGAGKG---PQGPGG------GGINVQEILTSIMG 590
Query: 524 CPNPGCGNQNFAWRTECNQCKAP-KPEGFLPP-----PFPP--PGGDRGR----GGPGG- 570
PN + ++ K P G L P FPP PGG +G GPGG
Sbjct: 591 SPNSHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGP 650
Query: 571 MRGGRGGLMDRGGPGGMFRGG-----RGGD----------RGG-FRGGRGMDRGGF--GG 612
M G GG GGP G G RGGD RGG RGG G G + G
Sbjct: 651 MPGPHGG---PGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGR 707
Query: 613 GRRGG--PGGPPGPLMEQMGGRRG-----GRGGP--GKMDKGEHR 648
G RGG P PP P GGR G GRGGP G + G HR
Sbjct: 708 GGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHR 752
Score = 35.8 bits (81), Expect = 0.13
Identities = 37/102 (36%), Positives = 41/102 (40%), Gaps = 29/102 (28%)
Query: 284 GFSGPGENRSMSGPDNRGRG-RGGFD-----------RGGMSRGGRGGGRGG-----MGS 326
G GPG GP +RGRG RGG + RGG S GG GRGG +G
Sbjct: 694 GGPGPGP-----GPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGG 748
Query: 327 AGER------GGF-NKPGGPMDEGPDLDLGPPVDPDEDSDNS 361
G R GG N G EGP +G P E S
Sbjct: 749 GGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGS 790
Score = 35.8 bits (81), Expect = 0.13
Identities = 24/76 (31%), Positives = 27/76 (35%)
Query: 265 SSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGM 324
SS + H G G GPG + G G GG GG G GGM
Sbjct: 764 SSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGM 823
Query: 325 GSAGERGGFNKPGGPM 340
G+ G PGG M
Sbjct: 824 GAGGGHRPHEGPGGSM 839
Score = 32.0 bits (71), Expect = 1.9
Identities = 27/75 (36%), Positives = 30/75 (40%), Gaps = 6/75 (8%)
Query: 274 SMGVYG----QESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGE 329
SMG G E G GP +R P +RG G RG G G GG G G
Sbjct: 838 SMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRG-PPPHEHRGHDGPGHGGGGHRGH 896
Query: 330 RGGFNKPGGPMDEGP 344
GG + GG M P
Sbjct: 897 DGG-HSHGGDMSNRP 910
Score = 30.8 bits (68), Expect = 4.1
Identities = 23/62 (37%), Positives = 24/62 (38%), Gaps = 10/62 (16%)
Query: 283 GGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDE 342
GG SG +R GP GG GG R G G GS G GG GP
Sbjct: 805 GGISGGSGHRPHEGPG------GGMGAGGGHRPHEGPG----GSMGGSGGHRPHEGPGHG 854
Query: 343 GP 344
GP
Sbjct: 855 GP 856
Score = 29.6 bits (65), Expect = 9.2
Identities = 24/68 (35%), Positives = 26/68 (38%), Gaps = 2/68 (2%)
Query: 283 GGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPM-D 341
GG G G +R GP G GG GG GG G G GG GG
Sbjct: 774 GGGMGSG-HRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPH 832
Query: 342 EGPDLDLG 349
EGP +G
Sbjct: 833 EGPGGSMG 840
>gi|48762934 alpha 2 type I collagen [Homo sapiens]
Length = 1366
Score = 82.0 bits (201), Expect = 2e-15
Identities = 137/480 (28%), Positives = 159/480 (33%), Gaps = 95/480 (19%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 274
G+P G + G + G P P +G + S+ R P S
Sbjct: 346 GEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGS-PGS 404
Query: 275 MGVYGQES-GGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGF 333
G+ G + G GP +R SGP RG GR G G MG G
Sbjct: 405 RGLPGADGRAGVMGPPGSRGASGPAGV--------RGPNGDAGRPGEPGLMGPRG----- 451
Query: 334 NKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRT 393
PG P + GP GP P D I G G T
Sbjct: 452 -LPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEP---------GNIGFPGPKGPT 501
Query: 394 GQP-----MIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKD-------FQGSKLK 441
G P H L G P D + PP V+ G+ FQG
Sbjct: 502 GDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPP-GPQGVQGGKGEQGPPGPPGFQGLPGP 560
Query: 442 VSLARK--KPPMNSMRG--GLP----PREGRGMPPPLRGGPG--------GPGGPGGPMG 485
A + KP + G GLP PR RG PP G G GP GP GP G
Sbjct: 561 SGPAGEVGKPGERGLHGEFGLPGPAGPRGERG-PPGESGAAGPTGPIGSRGPSGPPGPDG 619
Query: 486 RMGGRG--GDRGGFPPRGP------RGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWR 537
G G G G P GP RG+ G P G G + NPG R
Sbjct: 620 NKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGA----R 675
Query: 538 TECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRG-----GPGGMFRG-- 590
AP P G G+ G GP G G RG +RG GP G F G
Sbjct: 676 GAPGAVGAPGPAG-----ATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNG-FAGPA 729
Query: 591 ------GRGGDRG--GFRGGRGM--DRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPG 640
G G+RG G +G G+ G G GP GPPGP G RG G PG
Sbjct: 730 GAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGP-----AGSRGDGGPPG 784
Score = 82.0 bits (201), Expect = 2e-15
Identities = 113/384 (29%), Positives = 135/384 (35%), Gaps = 74/384 (19%)
Query: 284 GFSGPGENRSMSGPDNRGRGRGGFDRGG-------MSRGGRGGGRGGMGSAGERGGFNKP 336
G GP N GP +GG G G G G +G GERG +
Sbjct: 520 GAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEF 579
Query: 337 GGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQP 396
G P GP + GPP + I +G + D NK G+P
Sbjct: 580 GLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDG-------------NK--GEP 624
Query: 397 MIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRG 456
+ + T P G + + P + A GK +G +RG
Sbjct: 625 GVVGAVG--TAGPSGPSGL-----PGERGAAGIPGGKGEKGEP-------------GLRG 664
Query: 457 --GLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGN 514
G P R+G RG PG G PG P G G RG + G P GP G RG+P G
Sbjct: 665 EIGNPGRDGA------RGAPGAVGAPG-PAGATGDRG-EAGAAGPAGPAGPRGSPGERGE 716
Query: 515 VQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPE-GFLPPPFP-----------PPG-- 560
V + G Q A K PK E G + P P PPG
Sbjct: 717 VGPAGPNGFAGPAGAAGQPGAKGER--GAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPA 774
Query: 561 GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGMDRGGFGGGRR 615
G RG GGP GM G G G PG G G G G RG RG D+G G
Sbjct: 775 GSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRG-DQGPVGRTGE 833
Query: 616 GGPGGPPGPLMEQMGGRRGGRGGP 639
G GPPG E+ G GP
Sbjct: 834 VGAVGPPGFAGEKGPSGEAGTAGP 857
Score = 77.8 bits (190), Expect = 3e-14
Identities = 132/472 (27%), Positives = 163/472 (34%), Gaps = 87/472 (18%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQ-DHPS 273
G + G G Q G+Q P P G PS + + G++ + P
Sbjct: 526 GNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGL--PGPSGPAGEVGKPGERGLHGEFGLPG 583
Query: 274 SMGVYGQ-----ESG--GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGS 326
G G+ ESG G +GP +R SGP +G + G + G G G G
Sbjct: 584 PAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKG--EPGVVGAVGTAGPSGPSGL 641
Query: 327 AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGV 386
GERG PGG ++G G +P D +G +V A G
Sbjct: 642 PGERGAAGIPGGKGEKGEPGLRGEIGNPGRDG------ARGAPGAVGAPGPAGATGDRGE 695
Query: 387 VKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLAR 446
G P G E A F G + A
Sbjct: 696 AGAAGPAG--------------PAGPRGSPGERGEVGPAGPNGFAGP---------AGAA 732
Query: 447 KKPPMNSMRGGLPPREGRGMPPPL----RGGPGGPGGPGGPMGRMGGRGGDRG--GFP-- 498
+P RG P+ G+ P GP GP GP GP G G GG G GFP
Sbjct: 733 GQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGD-GGPPGMTGFPGA 791
Query: 499 -----PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFL- 552
P GP G G P G AG P G+Q RT + A P GF
Sbjct: 792 AGRTGPPGPSGISGPPGPPGP----AGKEGLRGPR-GDQGPVGRT--GEVGAVGPPGFAG 844
Query: 553 ------------PPPFPPPGGDRGRGGPGGMRGGRG--GLMDRGG----PGGMFRGGRGG 594
PP P P G G G G+ G RG GL G PG + G G
Sbjct: 845 EKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPG 904
Query: 595 DRG--GFRGGRGMDRGGFGGGRRGGPG--GPPGPLMEQMGGRRGGRGGPGKM 642
RG G G G++ GR G PG GPPG + G +G RG PG +
Sbjct: 905 ARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPG--RDGQPGHKGERGYPGNI 954
Score = 74.3 bits (181), Expect = 3e-13
Identities = 134/504 (26%), Positives = 157/504 (31%), Gaps = 70/504 (13%)
Query: 173 PQVPGSYPMQPVTAPPSYP----PTSYSSTQPTSYDQSSYSQ-QNTYGQPSSYGQQSSYG 227
P PG T PP P P YD G G + G
Sbjct: 47 PGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPRGPPGAAG 106
Query: 228 QQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQD-HPSSMGVYGQESGGFS 286
G Q P P + G A ++ G +D HP G G+ G
Sbjct: 107 APGPQGFQGPAGEPGEPGQTGPAGAR-----GPAGPPGKAGEDGHPGKPGRPGER--GVV 159
Query: 287 GPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDL 346
GP R G G GF +G G G +G G+ G +G +PG P + G
Sbjct: 160 GPQGARGFPGTP----GLPGF-KGIRGHNGLDGLKGQPGAPGVKG---EPGAPGENGTPG 211
Query: 347 DLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKET 406
G P E A G S D G + G P
Sbjct: 212 QTGARGLPGERGRVGAPGPAGARGS---DGSVGPVGPAGPIGSAGPPGFP--------GA 260
Query: 407 GKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK----PPMNSMRGGLPPRE 462
PKG+ P A G + +V L PP N GL +
Sbjct: 261 PGPKGEIGAVGNAGPAGPA-----------GPRGEVGLPGLSGPVGPPGNPGANGLTGAK 309
Query: 463 GRGMPPPLRGGPG--GPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAG 520
G P + G PG GP G GP+G G G RG GP GS+G SG AG
Sbjct: 310 GAAGLPGVAGAPGLPGPRGIPGPVGAAGATGA-RGLVGEPGPAGSKGE-SGNKGEPGSAG 367
Query: 521 DWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPP-------------FPPPGGDRGRGG 567
P P E P P G P P G RG G
Sbjct: 368 PQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASG 427
Query: 568 PGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGF-RGGRGMDRGGFGGGRRGGPGGPPGPLM 626
P G+RG G G PG M G G G G+ G G R GP GP G
Sbjct: 428 PAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARG 487
Query: 627 EQ----MGGRRGGRGGPGKM-DKG 645
E G +G G PGK DKG
Sbjct: 488 EPGNIGFPGPKGPTGDPGKNGDKG 511
Score = 73.2 bits (178), Expect = 7e-13
Identities = 151/550 (27%), Positives = 190/550 (34%), Gaps = 115/550 (20%)
Query: 188 PSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSY 247
P PP + + P + Q + GQ G + G G+ P + G
Sbjct: 98 PRGPPGAAGAPGPQGF-QGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGER 156
Query: 248 SQAPSQYSQQSSSYGQQSSFR--QDHPSSMGVYGQESG-GFSG----PGENRSMSGPDNR 300
Q ++ F+ + H G+ GQ G G PGEN + R
Sbjct: 157 GVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGAR 216
Query: 301 G----RGRGGFDRGGMSRGGRG-----GGRGGMGSAGERGGFNKPG-------------- 337
G RGR G +RG G G G +GSAG G PG
Sbjct: 217 GLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPA 276
Query: 338 ---GPMDE----GPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMN 390
GP E G +GPP +P + A GL L G V
Sbjct: 277 GPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAA 336
Query: 391 KRTGQPMIHIYLDKETGKP-----------KGDATVSYEDPPTAKAAVEWFDGKDFQGSK 439
TG + G+P KG+ + P + E G + +
Sbjct: 337 GATGARGL-------VGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAG- 388
Query: 440 LKVSLARKKPPMNSMRG-----GLPPREGRG--MPPPLRGGPGGPGGPGGPMGRMGGRGG 492
S PP +RG GLP +GR M PP G GP G GP G GR G
Sbjct: 389 ---SAGPPGPP--GLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGD-AGRPG 442
Query: 493 DRGGFPPRGPRGSRGN--PSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEG 550
+ G PRG GS GN P+G G P P G R E P P+G
Sbjct: 443 EPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGP-IGPAGA--RGEPGNIGFPGPKG 499
Query: 551 FLPPP----------------FPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGM-FRG--G 591
P P P G+ G GP G +G +GG ++G PG F+G G
Sbjct: 500 PTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPG 559
Query: 592 RGGDRG--GFRGGRGMDRGGFG-------GGRRGGPG-----GPPGPLMEQMGGRRGGRG 637
G G G G RG+ G FG G RG PG GP GP+ G RG G
Sbjct: 560 PSGPAGEVGKPGERGL-HGEFGLPGPAGPRGERGPPGESGAAGPTGPI-----GSRGPSG 613
Query: 638 GPG-KMDKGE 646
PG +KGE
Sbjct: 614 PPGPDGNKGE 623
Score = 72.0 bits (175), Expect = 2e-12
Identities = 69/199 (34%), Positives = 81/199 (40%), Gaps = 34/199 (17%)
Query: 470 LRGGPGGPGGPGGPMGRMG--GRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNP 527
+R GP G GP G G G GR G+ G P GP G G P GGN A +
Sbjct: 30 VRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNF---AAQYDGKGV 86
Query: 528 GCGNQNFAW---RTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGP 584
G G R AP P+GF P P G+ G+ GP G RG G G
Sbjct: 87 GLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEP--GEPGQTGPAGARGPAGPPGKAGED 144
Query: 585 GGMFRGGRGGDRG-----------------GFRGGRGMDRGGFGG--GRRGGPG--GPPG 623
G + GR G+RG GF+G RG G G G+ G PG G PG
Sbjct: 145 GHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRG--HNGLDGLKGQPGAPGVKGEPG 202
Query: 624 -PLMEQMGGRRGGRGGPGK 641
P G+ G RG PG+
Sbjct: 203 APGENGTPGQTGARGLPGE 221
Score = 71.6 bits (174), Expect = 2e-12
Identities = 104/367 (28%), Positives = 129/367 (35%), Gaps = 52/367 (14%)
Query: 317 RGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDD 376
R G G G GERG PG ++GP GPP P Q V L
Sbjct: 31 RKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGP 90
Query: 377 LADFFKQCGVVKMNKRTGQ-----PMIHIYLDKETGKPKGDATVSYEDP--PTAKAAVEW 429
G++ G P E G+P P P KA +
Sbjct: 91 -----GPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDG 145
Query: 430 FDGKDFQGSKLKV---SLARKKPPMNSMRG--------GLPPREGRGMPPPLRGGPGGPG 478
GK + + V AR P + G GL +G+ P ++G PG PG
Sbjct: 146 HPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPG 205
Query: 479 GPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGC------- 529
G P G+ G RG G+RG GP G+RG+ G V PG
Sbjct: 206 ENGTP-GQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPK 264
Query: 530 GNQNFAWRTECNQCKAPKPEGFLP---PPFPPPG--------GDRGRGGPGGMRGGRGGL 578
G P+ E LP P PPG G +G G G+ G G
Sbjct: 265 GEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLP 324
Query: 579 MDRGGPGGMFRGGRGGDRG-----GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRR 633
RG PG + G G RG G G +G + G G GP GPPGP E+ G+R
Sbjct: 325 GPRGIPGPVGAAGATGARGLVGEPGPAGSKG-ESGNKGEPGSAGPQGPPGPSGEE--GKR 381
Query: 634 GGRGGPG 640
G G G
Sbjct: 382 GPNGEAG 388
Score = 68.2 bits (165), Expect = 2e-11
Identities = 122/483 (25%), Positives = 152/483 (31%), Gaps = 93/483 (19%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 274
G+P G +G G + P ++G+ + S + P
Sbjct: 568 GKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPT-GPIGSRGPSGPPGPDGNKGEPGV 626
Query: 275 MGVYGQE--SGGFSGPGENRSMSGPDNRG-RGRGGFDRGGMSRGGRGGGRGGMGSAGERG 331
+G G SG PGE + P +G +G G RG + GR G RG G+ G G
Sbjct: 627 VGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGL-RGEIGNPGRDGARGAPGAVGAPG 685
Query: 332 GFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNK 391
G + G GP + + G N G
Sbjct: 686 PAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPN---------------GFAGPAG 730
Query: 392 RTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPM 451
GQP ++ PKG+ V P A +G S PP
Sbjct: 731 AAGQPGAKG--ERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAG----SRGDGGPPG 784
Query: 452 NSMRGGLPPREGRGMPPPLRG--GPGGPGGPGGPMGRMGGRG--------GDRGGFPPRG 501
+ G P GR PP G GP GP GP G G G RG G+ G P G
Sbjct: 785 MT---GFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPG 841
Query: 502 PRGSRGNPSGGGNVQHRAGDWQCPNP--------------GCGNQNFAWRTECNQCKAPK 547
G +G PSG AG P P G + P
Sbjct: 842 FAGEKG-PSGEAGT---AGPPGTPGPQGLLGAPGILGLPGSRGERGLPG--VAGAVGEPG 895
Query: 548 PEGFLPPPFP--PPG-----------------GDRGRGGPGGMRGGRGGLMDRGGPGGMF 588
P G PP PPG G+ G GP G G G +RG PG +
Sbjct: 896 PLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIG 955
Query: 589 RGGRGGDRG--------GFRGGRGM--DRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGG 638
G G G G G RG G G GP GP GP G RG +G
Sbjct: 956 PVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGP-----QGIRGDKGE 1010
Query: 639 PGK 641
PG+
Sbjct: 1011 PGE 1013
Score = 67.8 bits (164), Expect = 3e-11
Identities = 123/444 (27%), Positives = 157/444 (35%), Gaps = 82/444 (18%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 274
GQP + G++ + G + G PT P + P+ + S G P
Sbjct: 733 GQPGAKGERGAKGPKGENGVVGPTG--PVGAAGPAGPNGPPGPAGSRGDGGP-----PGM 785
Query: 275 MGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFN 334
G G + G +GP +SGP G + G+ RG RG +G +G GE G
Sbjct: 786 TGFPG--AAGRTGPPGPSGISGPPGPPGPAG---KEGL-RGPRGD-QGPVGRTGEVGAVG 838
Query: 335 KPGGPMDEGPDLDLG---PPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNK 391
PG ++GP + G PP P QGL + + L + G+ +
Sbjct: 839 PPGFAGEKGPSGEAGTAGPPGTPGP---------QGLLGAPGILGLPGSRGERGLPGVAG 889
Query: 392 RTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPM 451
G+P P G A PP A+ G+ + R P
Sbjct: 890 AVGEP-----------GPLGIA-----GPPGARGPPGAVGSPGVNGAPGEAG--RDGNPG 931
Query: 452 NSM---RGGLPPREG-RGMP----PPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPR 503
N R G P +G RG P P G GP GP GP G+ G R G+ G P GP
Sbjct: 932 NDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNR-GETGPSGPVGPA 990
Query: 504 GSRGNPSGGGNVQHRAGDWQCPN-------PGCGNQNFAWRTECNQCKAPKPEGFLPPPF 556
G+ G P G Q GD P PG N +G P
Sbjct: 991 GAVG-PRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGL-------------QGL--PGI 1034
Query: 557 PPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGR 614
GD+G G G G RG G G R G G G G RG +G G
Sbjct: 1035 AGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQ----GPAG 1090
Query: 615 RGGPGGPPGPLMEQMGGRRGGRGG 638
GP GPPGP GG G G
Sbjct: 1091 PPGPPGPPGPPGVSGGGYDFGYDG 1114
Score = 63.5 bits (153), Expect = 6e-10
Identities = 142/556 (25%), Positives = 178/556 (32%), Gaps = 118/556 (21%)
Query: 136 PTRPQDGNKPTETSQPQSSTG--GYNQPSLGYG-QSNYSYPQVPGSYPMQPVTAPPSYPP 192
P P+ P S TG G PS G N P V G+ + P P
Sbjct: 584 PAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPG 643
Query: 193 TSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQA-P 251
++ P + + G+ + G+ + G + G P G A P
Sbjct: 644 ERGAAGIPGGKGEKG--EPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGP 701
Query: 252 SQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGF--DR 309
+ + S G++ P+ +G GE R GP +G G
Sbjct: 702 AGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGE-RGAKGP----KGENGVVGPT 756
Query: 310 GGMSRGGRGGGRGGMGSAGERGGFNKPG-----------GPMDEGPDLDLGPPVDPDEDS 358
G + G G G G AG RG PG GP GP GPP P
Sbjct: 757 GPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGP--PGPSGISGPPGPPGPAG 814
Query: 359 DNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYE 418
+G V + G V G+ P G+A +
Sbjct: 815 KEGLRGPRGDQGPVGRTG------EVGAVGPPGFAGEK-----------GPSGEAGTA-- 855
Query: 419 DPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPG 478
PP G L S + P + G P G PP RG PG G
Sbjct: 856 GPPGTPGPQGLLGAPGILG--LPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVG 913
Query: 479 GPG-----GPMGRMGGRGGD----RGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGC 529
PG G GR G G D R G P G +G RG P G V
Sbjct: 914 SPGVNGAPGEAGRDGNPGNDGPPGRDGQP--GHKGERGYPGNIGPV-------------- 957
Query: 530 GNQNFAWRTECNQCKAPKPEGFLPPPFPPPG--GDRGRGGPGGMRGGRGGLMDRG--GPG 585
AP P G P P G G+RG GP G G G + RG GP
Sbjct: 958 -----------GAAGAPGPHG----PVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQ 1002
Query: 586 GMFRGGRG-----GDRG--GFRGGRGM-----------DRGGFGG-GRRG--GPGGPPGP 624
G+ RG +G G RG G +G G+ D+G G G G GP GP GP
Sbjct: 1003 GI-RGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGP 1061
Query: 625 LMEQMGGRRGGRGGPG 640
G+ G G PG
Sbjct: 1062 -----AGKDGRTGHPG 1072
Score = 33.1 bits (74), Expect = 0.83
Identities = 89/404 (22%), Positives = 117/404 (28%), Gaps = 76/404 (18%)
Query: 134 TAPTRPQDGNKPTETSQPQSSTGGYNQPSL-GY-GQSNYSYPQVPGSYPMQPVTAPPSYP 191
T P P P S G P + G+ G + + P P ++ PP P
Sbjct: 756 TGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSG-----ISGPPGPP 810
Query: 192 -PTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQA 250
P + DQ + G G G G P P G A
Sbjct: 811 GPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLG-A 869
Query: 251 PSQYSQQSSSYGQQS----SFRQDHPSSMGVYGQES-----GGFSGPGENRSMSGPDNRG 301
P S G++ + P +G+ G G PG N P G
Sbjct: 870 PGILGLPGSR-GERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVN---GAPGEAG 925
Query: 302 RGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNS 361
R + G R G+ G +G G G G G P GP G + E +
Sbjct: 926 RDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSG 985
Query: 362 AIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPP 421
+ G V +G I +GD E P
Sbjct: 986 PV------------------GPAGAVGPRGPSGPQGI-----------RGDKGEPGEKGP 1016
Query: 422 TAKAAVEWFDG----------KDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLR 471
++ +G QG+ V A + P G ++GR P
Sbjct: 1017 RGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGP--SGPAGKDGRTGHP--- 1071
Query: 472 GGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNP--SGGG 513
G GP G GP G G G P GP G G P SGGG
Sbjct: 1072 -GTVGPAGIRGPQGHQGPAG-------PPGPPGPPGPPGVSGGG 1107
>gi|153252068 testes-specific heterogenous nuclear ribonucleoprotein
G-T [Homo sapiens]
Length = 392
Score = 82.0 bits (201), Expect = 2e-15
Identities = 96/316 (30%), Positives = 117/316 (37%), Gaps = 73/316 (23%)
Query: 403 DKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPRE 462
D+ET K +G A V++E P AKAA +GK G +KV+ A KP S R G PP
Sbjct: 42 DRETNKSRGFAFVTFESPADAKAAARDMNGKSLDGKAIKVAQA-TKPAFESSRRGPPPPR 100
Query: 463 GRGMPPPLRGGPGGPGGPGGPMGRMGGRGG--DRGGF-------------------PPR- 500
RG P LRG GG GGP R RGG D GG+ PPR
Sbjct: 101 SRGRPRFLRGTRGGGGGP----RRSPSRGGPDDDGGYTADFDLRPSRAPMPMKRGPPPRR 156
Query: 501 -GPRGSRGNPSG-----GGNVQHRA------------------GDWQCPNPGCGNQNFAW 536
GP R PSG GG ++ RA + P G ++ ++
Sbjct: 157 VGPPPKRAAPSGPARSSGGGMRGRALAVRGRDGYSGPPRREPLPPRRDPYLGPRDEGYSS 216
Query: 537 RTECNQCKAPKPEGFLPPPFP---------------PPGGDRGRGGPGGMRGGRGGLMDR 581
R + +P GF P P P G R G GG G + R
Sbjct: 217 RDGYSSRDYREPRGFAPSPGEYTHRDYGHSSVRDDCPLRGYSDRDGYGGRDRDYGDHLSR 276
Query: 582 GGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 641
G F G+ G GRG GGGR G GGR G+
Sbjct: 277 GSHREPFES--YGELRGAAPGRGTPPSYGGGGRYEEYRGYSPDAYS--GGRDSYSSSYGR 332
Query: 642 MD---KGEHRQERRDR 654
D +G HR R DR
Sbjct: 333 SDRYSRGRHRVGRPDR 348
>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
sapiens]
Length = 1424
Score = 81.3 bits (199), Expect = 3e-15
Identities = 127/464 (27%), Positives = 174/464 (37%), Gaps = 63/464 (13%)
Query: 204 DQSSY-SQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQA--PSQYSQQSSS 260
D+S + + + G P G+ GQ+ G P + G P
Sbjct: 847 DRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPP 906
Query: 261 YGQQSSFRQDHPSSMGVYGQE-SGGFSGPGENRSMSGPDNRG-----RGRGGFDRGGMSR 314
+ ++ P GV GQ + G G ++ GP +G G +G
Sbjct: 907 GNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGL-KGFAGN 965
Query: 315 GGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTL 374
G G RG G G +G PG GP DLG +P E ++G+ S+
Sbjct: 966 PGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG------LRGIPGSMGN 1019
Query: 375 DDLADFFKQCGVVKMNKRTGQPM---IHIYLDKETGKPK-GDATVSYEDPPTAKAAVEWF 430
+ + G + R G+P IH L + G+P + T PT +
Sbjct: 1020 MGMPGSKGKRGTLGFPGRAGRPGLPGIH-GLQGDKGEPGYSEGTRPGPPGPTGDPGLPGD 1078
Query: 431 DGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG--GPMGRMG 488
GK K + + PP G L P G P G PG PG PG GP G +G
Sbjct: 1079 MGK-------KGEMGQPGPP-----GHLGPAGPEGAP----GSPGSPGLPGKPGPHGDLG 1122
Query: 489 GRGGDRGGFPP--RGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAP 546
+G PP RGP G G P G + R + PG + + E +AP
Sbjct: 1123 FKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGE----KGETGLLRAP 1178
Query: 547 KPEGFLPPPFPPPG-----GDRGRGGPGGMRGGRGGLMDRG--GPGGMFR-GGRGGDRGG 598
P P PG GDRG G G+ G +G + D G GP G+ G G G
Sbjct: 1179 ------PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGA 1232
Query: 599 FRGGRGMDRGGFGGGRRGGPG--GPPGPLMEQMGGRRGGRGGPG 640
G+ +RG G RG PG GPPGP + G +G +G G
Sbjct: 1233 IIPGQTGNRGP--PGSRGSPGAPGPPGPPGSHVIGIKGDKGSMG 1274
Score = 72.0 bits (175), Expect = 2e-12
Identities = 140/521 (26%), Positives = 181/521 (34%), Gaps = 88/521 (16%)
Query: 187 PPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGS 246
P P SY S + D + G P G + G + G Q G
Sbjct: 275 PSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGD 334
Query: 247 YS----QAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRG- 301
+ P++Y G + + P G G + G SGP G G
Sbjct: 335 IGPPGFRGPTEYYDTYQEKGDEGT--PGPPGPRGARGPQ--GPSGPPGVPGSPGSSRPGL 390
Query: 302 RGRGGFDRGGMSRGGRGG-GRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN 360
RG G+ S+G RG G+ MG+ G G PG P GP GPP D
Sbjct: 391 RGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPP---GPPGD------- 440
Query: 361 SAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHI----YLDKETGKPKGDATVS 416
++ +G L + G+ ++ G+P + Y+ G P
Sbjct: 441 -IVFRKGPPGD---HGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHG 496
Query: 417 YEDPPTAKAAVEWFDGKDFQGSKLKVSL--------ARKKPPMNSMRGGLPPREGR-GMP 467
+ P + A K GS L A+ P + +G EG+ G+P
Sbjct: 497 VKGIPGRQGAAGL---KGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVP 553
Query: 468 --PPLRGGPGG------PGGPG-----GPMGRMG--GRGGDRG--------GFP-PRGPR 503
P LRG PG PG PG GP G + G GD+G G P P GP
Sbjct: 554 GDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPA 613
Query: 504 GSRG-NPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGD 562
G G P G +Q G P P R E + P P PP P P G
Sbjct: 614 GPPGYGPQGEPGLQGTQGVPGAPGPP---GEAGPRGELS-VSTPVPG---PPGPPGPPGH 666
Query: 563 RGRGGPGGMRGGRGGLMDRGGPG--------GMFRGGRGGDRG--GFRGGRGMDRGGFGG 612
G GP G+ G G D G PG G+ G G +G GF G +G
Sbjct: 667 PGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKM 726
Query: 613 GRRGGPGGP--PGPLMEQMGGRRGGRGGPG----KMDKGEH 647
G G PG P PG E GG G PG + + GEH
Sbjct: 727 GEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEH 767
Score = 70.9 bits (172), Expect = 4e-12
Identities = 144/582 (24%), Positives = 192/582 (32%), Gaps = 65/582 (11%)
Query: 110 ASYAAQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSN 169
A A YG Q G Q AP P + E S G P
Sbjct: 610 AGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGP 669
Query: 170 YSYPQVPGSY-----PMQP-VTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQ 223
P +PGS P P P P + DQ + + G P G+
Sbjct: 670 QGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEP 729
Query: 224 SSYGQQSSYGQ--QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQE 281
G+ G +P + P G+ P ++ +S P G G E
Sbjct: 730 GLPGKPGLPGAKGEPAVAMPGGPGT----PGFPGERGNSGEHGEIGLPGLPGLPGTPGNE 785
Query: 282 SGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMD 341
G GP + GP G G G G G G G RG G P
Sbjct: 786 --GLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGI 843
Query: 342 EGPDL-----DLGPPVDPDEDSDNSAIYVQGLNDSVTL------DDLADFFKQCGVVKMN 390
G D + G P P + + +G + + D + G +
Sbjct: 844 PGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPP 903
Query: 391 KRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARK-KP 449
G P + G P P AK E D + S++ + K +P
Sbjct: 904 GPPGNP----GTPGQRGSPGIPGVKGQRGTPGAKG--EQGDKGNPGPSEISHVIGDKGEP 957
Query: 450 PMNSMRGGLPPREGRGMP--PPLRG--GPGGPGGPGGPMGRMGGRG--GDRG--GFPPRG 501
+ G + RG+P P L+G G GP GP GP G +G G G+ G G P G
Sbjct: 958 GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIP--G 1015
Query: 502 PRGSRGNPSGGGNVQHRAGDWQCPNPGC----GNQNFAWRTECNQCKAPKPEGFLPPPFP 557
G+ G P G + PG G Q ++ P P G P
Sbjct: 1016 SMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGL 1075
Query: 558 P----PGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFG 611
P G+ G+ GP G G G G PG G+ G G GF+G +G+ G
Sbjct: 1076 PGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGL----LG 1131
Query: 612 -GGRRGGPG-----GPPGPLMEQMGGRRGGRGGPGKM-DKGE 646
G RG PG G PGP+ + G +G G PG +KGE
Sbjct: 1132 PPGIRGPPGLPGFPGSPGPM--GIRGDQGRDGIPGPAGEKGE 1171
Score = 66.6 bits (161), Expect = 7e-11
Identities = 136/517 (26%), Positives = 166/517 (32%), Gaps = 84/517 (16%)
Query: 173 PQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSY 232
P PGS P P A P+ PP +P Q T G P + G G +
Sbjct: 598 PGDPGS-PGSPGPAGPAGPPGYGPQGEP--------GLQGTQGVPGAPGPPGEAGPRGEL 648
Query: 233 GQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENR 292
P PP P P G G GF GP
Sbjct: 649 SVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGP---- 704
Query: 293 SMSGPDNRGRGRGGFD--RGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGP 350
GP +G GF +G + G+ G G G G G +P M GP G
Sbjct: 705 --PGP----KGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP----GT 754
Query: 351 PVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKP- 409
P P E ++ G + + L L G ++ G P + G P
Sbjct: 755 PGFPGERGNS------GEHGEIGLPGLPGLPGTPGNEGLDGPRGDP-------GQPGPPG 801
Query: 410 -KGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVS---------LARKKPPMNSMRGGLP 459
+G E P A+ K QG + K L R P + G+P
Sbjct: 802 EQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIP 861
Query: 460 PREGRGMPPPLRGGPGGPG--GPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQH 517
+G P RG PG PG GP G G +G G G P GP G+ G P G+
Sbjct: 862 GHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFP-GAIGPPGPPGNPGTPGQRGSPGI 920
Query: 518 RAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGG 577
Q PG + Q P P GD+G G G G G
Sbjct: 921 PGVKGQRGTPGAKGE---------QGDKGNPG---PSEISHVIGDKGEPGLKGFAGNPGE 968
Query: 578 LMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGG----GRRGGPGGPPGPLMEQMGG 631
+RG PG G G G G G RG D G G G RG PG M G
Sbjct: 969 KGNRGVPGMPGLKGLKGLPGPAGPPGPRG-DLGSTGNPGEPGLRGIPGSMGNMGMPGSKG 1027
Query: 632 RRGGRGGPGKM-------------DKGEHRQERRDRP 655
+RG G PG+ DKGE RP
Sbjct: 1028 KRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRP 1064
Score = 65.9 bits (159), Expect = 1e-10
Identities = 112/408 (27%), Positives = 142/408 (34%), Gaps = 63/408 (15%)
Query: 268 RQDHPSSMGVYG-QESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGS 326
R P G++G Q G G E P G D G G+ G G +G
Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGP 1096
Query: 327 AGERGGFNKPGGPM---DEGPDLDL---------------GPPVDPDEDSDNSAIYVQGL 368
AG G PG P GP DL GPP P + ++G
Sbjct: 1097 AGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGD 1156
Query: 369 NDSVTLDDLADFFKQCGVVKMNKRT-GQPMIHIYLDKETGKP-----KGDATVSYEDPPT 422
+ A + G+++ G P + G P G + P
Sbjct: 1157 QGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQ-GAKGDRGAPGFPGLPGRKGAMGDAGPR 1215
Query: 423 AKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGL-PPREGRGMPPPLRGGPGGPGGPG 481
+E F G PP + G + P + G PP RG PG PG PG
Sbjct: 1216 GPTGIEGFPG----------------PP--GLPGAIIPGQTGNRGPPGSRGSPGAPGPPG 1257
Query: 482 GPMGRMGGRGGDRG--GFP-PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRT 538
P + G GD+G G P P+GP G+ G+ G + G P P G+ F
Sbjct: 1258 PPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRL-GAPGTPGLPGPR-GDPGFQGFP 1315
Query: 539 ECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG- 597
K GFL PP G G GP G+RG G L PG G G+ G
Sbjct: 1316 GVKGEKG--NPGFLGSIGPP--GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGM 1371
Query: 598 -GFRGGRGMDRGGFGGGRRGGPG-----GPPGPLMEQMGGRRGGRGGP 639
G G G G RG PG G PGP E+ G +G +G P
Sbjct: 1372 QGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEK--GNKGSKGEP 1417
Score = 62.4 bits (150), Expect = 1e-09
Identities = 134/517 (25%), Positives = 177/517 (34%), Gaps = 105/517 (20%)
Query: 154 STGGYNQ---PSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQ 210
+TG Y P + +P +PG+ P P + Q + + +
Sbjct: 113 NTGPYGLVGVPGCSGSKGEQGFPGLPGTLGY------PGIPGAAGLKGQKGAPAKEEDIE 166
Query: 211 QNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQD 270
+ G P G G G P PP + P + G
Sbjct: 167 LDAKGDPGLPGAPGPQGLPGPPGFPGPVG-PPGPPGFFGFPGAMGPRGPK-GHMGERVIG 224
Query: 271 HPSSMGVYGQESGGFSGPGENR-SMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGE 329
H GV G +G PG +++GPDNR G G +G MG G
Sbjct: 225 HKGERGVKGL-TGPPGPPGTVIVTLTGPDNR-----------TDLKGEKGDKGAMGEPGP 272
Query: 330 RGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKM 389
G PG E + G P DP GL D + F GV K
Sbjct: 273 PGPSGLPG----ESYGSEKGAPGDP------------GLQGKPGKDGVPGFPGSEGV-KG 315
Query: 390 NKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKP 449
N+ G P + + D G+ KGD PP + E++D +G + P
Sbjct: 316 NR--GFPGL-MGEDGIKGQ-KGDI-----GPPGFRGPTEYYDTYQEKGDE-----GTPGP 361
Query: 450 PMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPP-RGPRGSRGN 508
P PR RG P G PG PG PG R G RG G+P +G +G RG
Sbjct: 362 P--------GPRGARGPQGP-SGPPGVPGSPGS--SRPGLRGAP--GWPGLKGSKGERGR 408
Query: 509 PSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPP--------PG 560
P G + G +PGC +P G PP PP P
Sbjct: 409 P--GKDAMGTPG-----SPGCAG-------------SPGLPGSPGPPGPPGDIVFRKGPP 448
Query: 561 GDRGRGGPGGMRGGRGGLMDRGGPGGM-----FRGGRGGDRG--GFRGGRGMDRGGFGGG 613
GD G G G G G +G PG + + G G G G G +G+ G
Sbjct: 449 GDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAG 508
Query: 614 RRGGPGGPPGPLMEQMGGRRGGRGGPG-KMDKGEHRQ 649
+G PG P + G G +G PG K +KGE Q
Sbjct: 509 LKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQ 545
Score = 55.8 bits (133), Expect = 1e-07
Identities = 74/234 (31%), Positives = 91/234 (38%), Gaps = 63/234 (26%)
Query: 457 GLPPREG----RGMP--PPLRGGPGGPGGPG--GPMGRMG--GRGGDRG--GFP------ 498
GLP G RG+ P G PG PG PG GP G +G G G +G GFP
Sbjct: 82 GLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTL 141
Query: 499 -------PRGPRGSRGNPSGGGNVQHRA-GDWQCPNPGCGNQNFAWRTECNQCKAPKPEG 550
G +G +G P+ +++ A GD P G Q P P G
Sbjct: 142 GYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAP-GPQGL-----------PGPPG 189
Query: 551 FLPPPFPPPGGDRGRGGPGGM--RGGRGGLMDR-----------------GGPGGMFRGG 591
F P P PPG G PG M RG +G + +R G PG +
Sbjct: 190 F-PGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTL 248
Query: 592 RGGD-RGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDK 644
G D R +G +G D+G G GP G PG E G +G G PG K
Sbjct: 249 TGPDNRTDLKGEKG-DKGAMGEPGPPGPSGLPG---ESYGSEKGAPGDPGLQGK 298
Score = 46.2 bits (108), Expect = 9e-05
Identities = 61/190 (32%), Positives = 76/190 (40%), Gaps = 27/190 (14%)
Query: 471 RGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNP--SGGGNVQHRAG-DWQCPNP 527
+G PG PG PG G G G P+GP+G G P +G V+ +G +P
Sbjct: 51 KGFPGPPGSPG-----QKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSP 105
Query: 528 GC----GNQNFAWRTECNQCKAPKPE-GFLPPPFPPPGGDRGRGGPGGMRGGRGG----- 577
G GN C K E GF P P G G G G++G +G
Sbjct: 106 GLPGTPGNTGPYGLVGVPGCSGSKGEQGF--PGLPGTLGYPGIPGAAGLKGQKGAPAKEE 163
Query: 578 ---LMDRGGPGGMFRGGRGGDRG--GFRG--GRGMDRGGFGGGRRGGPGGPPGPLMEQMG 630
L +G PG G G G GF G G G FG GP GP G + E++
Sbjct: 164 DIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVI 223
Query: 631 GRRGGRGGPG 640
G +G RG G
Sbjct: 224 GHKGERGVKG 233
Score = 39.3 bits (90), Expect = 0.012
Identities = 81/318 (25%), Positives = 100/318 (31%), Gaps = 66/318 (20%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 274
G P S G G Q G P +TG P + + P
Sbjct: 1143 GFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGL 1202
Query: 275 MGVYGQ--ESG--------GFSGP---------GENRSMSGPDNRGRGRGGFDRG--GMS 313
G G ++G GF GP G+ + P +RG G G
Sbjct: 1203 PGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSH 1262
Query: 314 RGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVT 373
G G +G MG G +G PG D GP LG P P QG
Sbjct: 1263 VIGIKGDKGSMGHPGPKG---PPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPG--- 1316
Query: 374 LDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGK 433
VK K + I G PKG V DP T K
Sbjct: 1317 -------------VKGEKGNPGFLGSIGPPGPIG-PKGPPGVR-GDPGTLKI-------- 1353
Query: 434 DFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG--GRG 491
+SL P + G P +G PP GP G GP GP G+ G G+
Sbjct: 1354 --------ISLPGSPGPPGT--PGEPGMQGEPGPP----GPPGNLGPCGPRGKPGKDGKP 1399
Query: 492 GDRGGFPPRGPRGSRGNP 509
G G +G +GS+G P
Sbjct: 1400 GTPGPAGEKGNKGSKGEP 1417
Score = 32.3 bits (72), Expect = 1.4
Identities = 38/125 (30%), Positives = 48/125 (38%), Gaps = 27/125 (21%)
Query: 540 CNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-- 597
C+ K K E FP P G G+ G G G G +G PG G G RG
Sbjct: 41 CDGAKGEKGE----KGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGIS 96
Query: 598 ---GFRGGRGM-----DRGGFG-------GGRRGGPGGP--PG----PLMEQMGGRRGGR 636
GF G G+ + G +G G +G G P PG P + G +G +
Sbjct: 97 GLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQK 156
Query: 637 GGPGK 641
G P K
Sbjct: 157 GAPAK 161
>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
sapiens]
Length = 1494
Score = 81.3 bits (199), Expect = 3e-15
Identities = 127/464 (27%), Positives = 174/464 (37%), Gaps = 63/464 (13%)
Query: 204 DQSSY-SQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQA--PSQYSQQSSS 260
D+S + + + G P G+ GQ+ G P + G P
Sbjct: 847 DRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPP 906
Query: 261 YGQQSSFRQDHPSSMGVYGQE-SGGFSGPGENRSMSGPDNRG-----RGRGGFDRGGMSR 314
+ ++ P GV GQ + G G ++ GP +G G +G
Sbjct: 907 GNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGL-KGFAGN 965
Query: 315 GGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTL 374
G G RG G G +G PG GP DLG +P E ++G+ S+
Sbjct: 966 PGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG------LRGIPGSMGN 1019
Query: 375 DDLADFFKQCGVVKMNKRTGQPM---IHIYLDKETGKPK-GDATVSYEDPPTAKAAVEWF 430
+ + G + R G+P IH L + G+P + T PT +
Sbjct: 1020 MGMPGSKGKRGTLGFPGRAGRPGLPGIH-GLQGDKGEPGYSEGTRPGPPGPTGDPGLPGD 1078
Query: 431 DGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG--GPMGRMG 488
GK K + + PP G L P G P G PG PG PG GP G +G
Sbjct: 1079 MGK-------KGEMGQPGPP-----GHLGPAGPEGAP----GSPGSPGLPGKPGPHGDLG 1122
Query: 489 GRGGDRGGFPP--RGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAP 546
+G PP RGP G G P G + R + PG + + E +AP
Sbjct: 1123 FKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGE----KGETGLLRAP 1178
Query: 547 KPEGFLPPPFPPPG-----GDRGRGGPGGMRGGRGGLMDRG--GPGGMFR-GGRGGDRGG 598
P P PG GDRG G G+ G +G + D G GP G+ G G G
Sbjct: 1179 ------PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGA 1232
Query: 599 FRGGRGMDRGGFGGGRRGGPG--GPPGPLMEQMGGRRGGRGGPG 640
G+ +RG G RG PG GPPGP + G +G +G G
Sbjct: 1233 IIPGQTGNRGP--PGSRGSPGAPGPPGPPGSHVIGIKGDKGSMG 1274
Score = 72.0 bits (175), Expect = 2e-12
Identities = 140/521 (26%), Positives = 181/521 (34%), Gaps = 88/521 (16%)
Query: 187 PPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGS 246
P P SY S + D + G P G + G + G Q G
Sbjct: 275 PSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGD 334
Query: 247 YS----QAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRG- 301
+ P++Y G + + P G G + G SGP G G
Sbjct: 335 IGPPGFRGPTEYYDTYQEKGDEGT--PGPPGPRGARGPQ--GPSGPPGVPGSPGSSRPGL 390
Query: 302 RGRGGFDRGGMSRGGRGG-GRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN 360
RG G+ S+G RG G+ MG+ G G PG P GP GPP D
Sbjct: 391 RGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPP---GPPGD------- 440
Query: 361 SAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHI----YLDKETGKPKGDATVS 416
++ +G L + G+ ++ G+P + Y+ G P
Sbjct: 441 -IVFRKGPPGD---HGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHG 496
Query: 417 YEDPPTAKAAVEWFDGKDFQGSKLKVSL--------ARKKPPMNSMRGGLPPREGR-GMP 467
+ P + A K GS L A+ P + +G EG+ G+P
Sbjct: 497 VKGIPGRQGAAGL---KGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVP 553
Query: 468 --PPLRGGPGG------PGGPG-----GPMGRMG--GRGGDRG--------GFP-PRGPR 503
P LRG PG PG PG GP G + G GD+G G P P GP
Sbjct: 554 GDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPA 613
Query: 504 GSRG-NPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGD 562
G G P G +Q G P P R E + P P PP P P G
Sbjct: 614 GPPGYGPQGEPGLQGTQGVPGAPGPP---GEAGPRGELS-VSTPVPG---PPGPPGPPGH 666
Query: 563 RGRGGPGGMRGGRGGLMDRGGPG--------GMFRGGRGGDRG--GFRGGRGMDRGGFGG 612
G GP G+ G G D G PG G+ G G +G GF G +G
Sbjct: 667 PGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKM 726
Query: 613 GRRGGPGGP--PGPLMEQMGGRRGGRGGPG----KMDKGEH 647
G G PG P PG E GG G PG + + GEH
Sbjct: 727 GEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEH 767
Score = 70.9 bits (172), Expect = 4e-12
Identities = 144/582 (24%), Positives = 192/582 (32%), Gaps = 65/582 (11%)
Query: 110 ASYAAQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSN 169
A A YG Q G Q AP P + E S G P
Sbjct: 610 AGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGP 669
Query: 170 YSYPQVPGSY-----PMQP-VTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQ 223
P +PGS P P P P + DQ + + G P G+
Sbjct: 670 QGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEP 729
Query: 224 SSYGQQSSYGQ--QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQE 281
G+ G +P + P G+ P ++ +S P G G E
Sbjct: 730 GLPGKPGLPGAKGEPAVAMPGGPGT----PGFPGERGNSGEHGEIGLPGLPGLPGTPGNE 785
Query: 282 SGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMD 341
G GP + GP G G G G G G G RG G P
Sbjct: 786 --GLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGI 843
Query: 342 EGPDL-----DLGPPVDPDEDSDNSAIYVQGLNDSVTL------DDLADFFKQCGVVKMN 390
G D + G P P + + +G + + D + G +
Sbjct: 844 PGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPP 903
Query: 391 KRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARK-KP 449
G P + G P P AK E D + S++ + K +P
Sbjct: 904 GPPGNP----GTPGQRGSPGIPGVKGQRGTPGAKG--EQGDKGNPGPSEISHVIGDKGEP 957
Query: 450 PMNSMRGGLPPREGRGMP--PPLRG--GPGGPGGPGGPMGRMGGRG--GDRG--GFPPRG 501
+ G + RG+P P L+G G GP GP GP G +G G G+ G G P G
Sbjct: 958 GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIP--G 1015
Query: 502 PRGSRGNPSGGGNVQHRAGDWQCPNPGC----GNQNFAWRTECNQCKAPKPEGFLPPPFP 557
G+ G P G + PG G Q ++ P P G P
Sbjct: 1016 SMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGL 1075
Query: 558 P----PGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFG 611
P G+ G+ GP G G G G PG G+ G G GF+G +G+ G
Sbjct: 1076 PGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGL----LG 1131
Query: 612 -GGRRGGPG-----GPPGPLMEQMGGRRGGRGGPGKM-DKGE 646
G RG PG G PGP+ + G +G G PG +KGE
Sbjct: 1132 PPGIRGPPGLPGFPGSPGPM--GIRGDQGRDGIPGPAGEKGE 1171
Score = 68.2 bits (165), Expect = 2e-11
Identities = 113/409 (27%), Positives = 143/409 (34%), Gaps = 63/409 (15%)
Query: 268 RQDHPSSMGVYG-QESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGS 326
R P G++G Q G G E P G D G G+ G G +G
Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGP 1096
Query: 327 AGERGGFNKPGGPM---DEGPDLDL---------------GPPVDPDEDSDNSAIYVQGL 368
AG G PG P GP DL GPP P + ++G
Sbjct: 1097 AGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGD 1156
Query: 369 NDSVTLDDLADFFKQCGVVKMNKRT-GQPMIHIYLDKETGKP-----KGDATVSYEDPPT 422
+ A + G+++ G P + G P G + P
Sbjct: 1157 QGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQ-GAKGDRGAPGFPGLPGRKGAMGDAGPR 1215
Query: 423 AKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGL-PPREGRGMPPPLRGGPGGPGGPG 481
+E F G PP + G + P + G PP RG PG PG PG
Sbjct: 1216 GPTGIEGFPG----------------PP--GLPGAIIPGQTGNRGPPGSRGSPGAPGPPG 1257
Query: 482 GPMGRMGGRGGDRG--GFP-PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRT 538
P + G GD+G G P P+GP G+ G+ G + G P P G+ F
Sbjct: 1258 PPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRL-GAPGTPGLPGPR-GDPGFQGFP 1315
Query: 539 ECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG- 597
K GFL PP G G GP G+RG G L PG G G+ G
Sbjct: 1316 GVKGEKG--NPGFLGSIGPP--GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGM 1371
Query: 598 -GFRGGRGMDRGGFGGGRRGGPG-----GPPGPLMEQMGGRRGGRGGPG 640
G G G G RG PG G PGP E+ G +G +G PG
Sbjct: 1372 QGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEK--GNKGSKGEPG 1418
Score = 66.6 bits (161), Expect = 7e-11
Identities = 136/517 (26%), Positives = 166/517 (32%), Gaps = 84/517 (16%)
Query: 173 PQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSY 232
P PGS P P A P+ PP +P Q T G P + G G +
Sbjct: 598 PGDPGS-PGSPGPAGPAGPPGYGPQGEP--------GLQGTQGVPGAPGPPGEAGPRGEL 648
Query: 233 GQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENR 292
P PP P P G G GF GP
Sbjct: 649 SVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGP---- 704
Query: 293 SMSGPDNRGRGRGGFD--RGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGP 350
GP +G GF +G + G+ G G G G G +P M GP G
Sbjct: 705 --PGP----KGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP----GT 754
Query: 351 PVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKP- 409
P P E ++ G + + L L G ++ G P + G P
Sbjct: 755 PGFPGERGNS------GEHGEIGLPGLPGLPGTPGNEGLDGPRGDP-------GQPGPPG 801
Query: 410 -KGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVS---------LARKKPPMNSMRGGLP 459
+G E P A+ K QG + K L R P + G+P
Sbjct: 802 EQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIP 861
Query: 460 PREGRGMPPPLRGGPGGPG--GPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQH 517
+G P RG PG PG GP G G +G G G P GP G+ G P G+
Sbjct: 862 GHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFP-GAIGPPGPPGNPGTPGQRGSPGI 920
Query: 518 RAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGG 577
Q PG + Q P P GD+G G G G G
Sbjct: 921 PGVKGQRGTPGAKGE---------QGDKGNPG---PSEISHVIGDKGEPGLKGFAGNPGE 968
Query: 578 LMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGG----GRRGGPGGPPGPLMEQMGG 631
+RG PG G G G G G RG D G G G RG PG M G
Sbjct: 969 KGNRGVPGMPGLKGLKGLPGPAGPPGPRG-DLGSTGNPGEPGLRGIPGSMGNMGMPGSKG 1027
Query: 632 RRGGRGGPGKM-------------DKGEHRQERRDRP 655
+RG G PG+ DKGE RP
Sbjct: 1028 KRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRP 1064
Score = 62.4 bits (150), Expect = 1e-09
Identities = 134/517 (25%), Positives = 177/517 (34%), Gaps = 105/517 (20%)
Query: 154 STGGYNQ---PSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQ 210
+TG Y P + +P +PG+ P P + Q + + +
Sbjct: 113 NTGPYGLVGVPGCSGSKGEQGFPGLPGTLGY------PGIPGAAGLKGQKGAPAKEEDIE 166
Query: 211 QNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQD 270
+ G P G G G P PP + P + G
Sbjct: 167 LDAKGDPGLPGAPGPQGLPGPPGFPGPVG-PPGPPGFFGFPGAMGPRGPK-GHMGERVIG 224
Query: 271 HPSSMGVYGQESGGFSGPGENR-SMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGE 329
H GV G +G PG +++GPDNR G G +G MG G
Sbjct: 225 HKGERGVKGL-TGPPGPPGTVIVTLTGPDNR-----------TDLKGEKGDKGAMGEPGP 272
Query: 330 RGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKM 389
G PG E + G P DP GL D + F GV K
Sbjct: 273 PGPSGLPG----ESYGSEKGAPGDP------------GLQGKPGKDGVPGFPGSEGV-KG 315
Query: 390 NKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKP 449
N+ G P + + D G+ KGD PP + E++D +G + P
Sbjct: 316 NR--GFPGL-MGEDGIKGQ-KGDI-----GPPGFRGPTEYYDTYQEKGDE-----GTPGP 361
Query: 450 PMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPP-RGPRGSRGN 508
P PR RG P G PG PG PG R G RG G+P +G +G RG
Sbjct: 362 P--------GPRGARGPQGP-SGPPGVPGSPGS--SRPGLRGAP--GWPGLKGSKGERGR 408
Query: 509 PSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPP--------PG 560
P G + G +PGC +P G PP PP P
Sbjct: 409 P--GKDAMGTPG-----SPGCAG-------------SPGLPGSPGPPGPPGDIVFRKGPP 448
Query: 561 GDRGRGGPGGMRGGRGGLMDRGGPGGM-----FRGGRGGDRG--GFRGGRGMDRGGFGGG 613
GD G G G G G +G PG + + G G G G G +G+ G
Sbjct: 449 GDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAG 508
Query: 614 RRGGPGGPPGPLMEQMGGRRGGRGGPG-KMDKGEHRQ 649
+G PG P + G G +G PG K +KGE Q
Sbjct: 509 LKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQ 545
Score = 55.8 bits (133), Expect = 1e-07
Identities = 74/234 (31%), Positives = 91/234 (38%), Gaps = 63/234 (26%)
Query: 457 GLPPREG----RGMP--PPLRGGPGGPGGPG--GPMGRMG--GRGGDRG--GFP------ 498
GLP G RG+ P G PG PG PG GP G +G G G +G GFP
Sbjct: 82 GLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTL 141
Query: 499 -------PRGPRGSRGNPSGGGNVQHRA-GDWQCPNPGCGNQNFAWRTECNQCKAPKPEG 550
G +G +G P+ +++ A GD P G Q P P G
Sbjct: 142 GYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAP-GPQGL-----------PGPPG 189
Query: 551 FLPPPFPPPGGDRGRGGPGGM--RGGRGGLMDR-----------------GGPGGMFRGG 591
F P P PPG G PG M RG +G + +R G PG +
Sbjct: 190 F-PGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTL 248
Query: 592 RGGD-RGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDK 644
G D R +G +G D+G G GP G PG E G +G G PG K
Sbjct: 249 TGPDNRTDLKGEKG-DKGAMGEPGPPGPSGLPG---ESYGSEKGAPGDPGLQGK 298
Score = 52.8 bits (125), Expect = 1e-06
Identities = 55/172 (31%), Positives = 65/172 (37%), Gaps = 31/172 (18%)
Query: 447 KKPPMNSMRGGLPPREGR----GMPPPLRGGPGGPGGPG--GPMGRMGGRG--GDRGGFP 498
K PP + G P R G G+P P RG PG G PG G G G G G G
Sbjct: 1279 KGPPGTAGDMGPPGRLGAPGTPGLPGP-RGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIG 1337
Query: 499 PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPP 558
P+GP G RG+P + PG P +G PP PP
Sbjct: 1338 PKGPPGVRGDPGTLKIISLPGSPGPPGTPG----------------EPGMQGEPGPPGPP 1381
Query: 559 ----PGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRG 604
P G RG+ G G G G ++G G G G G G +G RG
Sbjct: 1382 GNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRG 1433
Score = 46.2 bits (108), Expect = 9e-05
Identities = 61/190 (32%), Positives = 76/190 (40%), Gaps = 27/190 (14%)
Query: 471 RGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNP--SGGGNVQHRAG-DWQCPNP 527
+G PG PG PG G G G P+GP+G G P +G V+ +G +P
Sbjct: 51 KGFPGPPGSPG-----QKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSP 105
Query: 528 GC----GNQNFAWRTECNQCKAPKPE-GFLPPPFPPPGGDRGRGGPGGMRGGRGG----- 577
G GN C K E GF P P G G G G++G +G
Sbjct: 106 GLPGTPGNTGPYGLVGVPGCSGSKGEQGF--PGLPGTLGYPGIPGAAGLKGQKGAPAKEE 163
Query: 578 ---LMDRGGPGGMFRGGRGGDRG--GFRG--GRGMDRGGFGGGRRGGPGGPPGPLMEQMG 630
L +G PG G G G GF G G G FG GP GP G + E++
Sbjct: 164 DIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVI 223
Query: 631 GRRGGRGGPG 640
G +G RG G
Sbjct: 224 GHKGERGVKG 233
Score = 41.2 bits (95), Expect = 0.003
Identities = 82/323 (25%), Positives = 102/323 (31%), Gaps = 66/323 (20%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 274
G P S G G Q G P +TG P + + P
Sbjct: 1143 GFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGL 1202
Query: 275 MGVYGQ--ESG--------GFSGP---------GENRSMSGPDNRGRGRGGFDRG--GMS 313
G G ++G GF GP G+ + P +RG G G
Sbjct: 1203 PGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSH 1262
Query: 314 RGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVT 373
G G +G MG G +G PG D GP LG P P QG
Sbjct: 1263 VIGIKGDKGSMGHPGPKG---PPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPG--- 1316
Query: 374 LDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGK 433
VK K + I G PKG V DP T K
Sbjct: 1317 -------------VKGEKGNPGFLGSIGPPGPIG-PKGPPGVR-GDPGTLKI-------- 1353
Query: 434 DFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG--GRG 491
+SL P + G P +G PP GP G GP GP G+ G G+
Sbjct: 1354 --------ISLPGSPGPPGT--PGEPGMQGEPGPP----GPPGNLGPCGPRGKPGKDGKP 1399
Query: 492 GDRGGFPPRGPRGSRGNPSGGGN 514
G G +G +GS+G P G+
Sbjct: 1400 GTPGPAGEKGNKGSKGEPGPAGS 1422
Score = 32.3 bits (72), Expect = 1.4
Identities = 38/125 (30%), Positives = 48/125 (38%), Gaps = 27/125 (21%)
Query: 540 CNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-- 597
C+ K K E FP P G G+ G G G G +G PG G G RG
Sbjct: 41 CDGAKGEKGE----KGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGIS 96
Query: 598 ---GFRGGRGM-----DRGGFG-------GGRRGGPGGP--PG----PLMEQMGGRRGGR 636
GF G G+ + G +G G +G G P PG P + G +G +
Sbjct: 97 GLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQK 156
Query: 637 GGPGK 641
G P K
Sbjct: 157 GAPAK 161
>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
sapiens]
Length = 1637
Score = 81.3 bits (199), Expect = 3e-15
Identities = 127/464 (27%), Positives = 174/464 (37%), Gaps = 63/464 (13%)
Query: 204 DQSSY-SQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQA--PSQYSQQSSS 260
D+S + + + G P G+ GQ+ G P + G P
Sbjct: 847 DRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPP 906
Query: 261 YGQQSSFRQDHPSSMGVYGQE-SGGFSGPGENRSMSGPDNRG-----RGRGGFDRGGMSR 314
+ ++ P GV GQ + G G ++ GP +G G +G
Sbjct: 907 GNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGL-KGFAGN 965
Query: 315 GGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTL 374
G G RG G G +G PG GP DLG +P E ++G+ S+
Sbjct: 966 PGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG------LRGIPGSMGN 1019
Query: 375 DDLADFFKQCGVVKMNKRTGQPM---IHIYLDKETGKPK-GDATVSYEDPPTAKAAVEWF 430
+ + G + R G+P IH L + G+P + T PT +
Sbjct: 1020 MGMPGSKGKRGTLGFPGRAGRPGLPGIH-GLQGDKGEPGYSEGTRPGPPGPTGDPGLPGD 1078
Query: 431 DGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG--GPMGRMG 488
GK K + + PP G L P G P G PG PG PG GP G +G
Sbjct: 1079 MGK-------KGEMGQPGPP-----GHLGPAGPEGAP----GSPGSPGLPGKPGPHGDLG 1122
Query: 489 GRGGDRGGFPP--RGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAP 546
+G PP RGP G G P G + R + PG + + E +AP
Sbjct: 1123 FKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGE----KGETGLLRAP 1178
Query: 547 KPEGFLPPPFPPPG-----GDRGRGGPGGMRGGRGGLMDRG--GPGGMFR-GGRGGDRGG 598
P P PG GDRG G G+ G +G + D G GP G+ G G G
Sbjct: 1179 ------PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGA 1232
Query: 599 FRGGRGMDRGGFGGGRRGGPG--GPPGPLMEQMGGRRGGRGGPG 640
G+ +RG G RG PG GPPGP + G +G +G G
Sbjct: 1233 IIPGQTGNRGP--PGSRGSPGAPGPPGPPGSHVIGIKGDKGSMG 1274
Score = 72.0 bits (175), Expect = 2e-12
Identities = 140/521 (26%), Positives = 181/521 (34%), Gaps = 88/521 (16%)
Query: 187 PPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGS 246
P P SY S + D + G P G + G + G Q G
Sbjct: 275 PSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGD 334
Query: 247 YS----QAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRG- 301
+ P++Y G + + P G G + G SGP G G
Sbjct: 335 IGPPGFRGPTEYYDTYQEKGDEGT--PGPPGPRGARGPQ--GPSGPPGVPGSPGSSRPGL 390
Query: 302 RGRGGFDRGGMSRGGRGG-GRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN 360
RG G+ S+G RG G+ MG+ G G PG P GP GPP D
Sbjct: 391 RGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPP---GPPGD------- 440
Query: 361 SAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHI----YLDKETGKPKGDATVS 416
++ +G L + G+ ++ G+P + Y+ G P
Sbjct: 441 -IVFRKGPPGD---HGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHG 496
Query: 417 YEDPPTAKAAVEWFDGKDFQGSKLKVSL--------ARKKPPMNSMRGGLPPREGR-GMP 467
+ P + A K GS L A+ P + +G EG+ G+P
Sbjct: 497 VKGIPGRQGAAGL---KGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVP 553
Query: 468 --PPLRGGPGG------PGGPG-----GPMGRMG--GRGGDRG--------GFP-PRGPR 503
P LRG PG PG PG GP G + G GD+G G P P GP
Sbjct: 554 GDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPA 613
Query: 504 GSRG-NPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGD 562
G G P G +Q G P P R E + P P PP P P G
Sbjct: 614 GPPGYGPQGEPGLQGTQGVPGAPGPP---GEAGPRGELS-VSTPVPG---PPGPPGPPGH 666
Query: 563 RGRGGPGGMRGGRGGLMDRGGPG--------GMFRGGRGGDRG--GFRGGRGMDRGGFGG 612
G GP G+ G G D G PG G+ G G +G GF G +G
Sbjct: 667 PGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKM 726
Query: 613 GRRGGPGGP--PGPLMEQMGGRRGGRGGPG----KMDKGEH 647
G G PG P PG E GG G PG + + GEH
Sbjct: 727 GEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEH 767
Score = 70.9 bits (172), Expect = 4e-12
Identities = 144/582 (24%), Positives = 192/582 (32%), Gaps = 65/582 (11%)
Query: 110 ASYAAQSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSN 169
A A YG Q G Q AP P + E S G P
Sbjct: 610 AGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGP 669
Query: 170 YSYPQVPGSY-----PMQP-VTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQ 223
P +PGS P P P P + DQ + + G P G+
Sbjct: 670 QGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEP 729
Query: 224 SSYGQQSSYGQ--QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQE 281
G+ G +P + P G+ P ++ +S P G G E
Sbjct: 730 GLPGKPGLPGAKGEPAVAMPGGPGT----PGFPGERGNSGEHGEIGLPGLPGLPGTPGNE 785
Query: 282 SGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMD 341
G GP + GP G G G G G G G RG G P
Sbjct: 786 --GLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGI 843
Query: 342 EGPDL-----DLGPPVDPDEDSDNSAIYVQGLNDSVTL------DDLADFFKQCGVVKMN 390
G D + G P P + + +G + + D + G +
Sbjct: 844 PGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPP 903
Query: 391 KRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARK-KP 449
G P + G P P AK E D + S++ + K +P
Sbjct: 904 GPPGNP----GTPGQRGSPGIPGVKGQRGTPGAKG--EQGDKGNPGPSEISHVIGDKGEP 957
Query: 450 PMNSMRGGLPPREGRGMP--PPLRG--GPGGPGGPGGPMGRMGGRG--GDRG--GFPPRG 501
+ G + RG+P P L+G G GP GP GP G +G G G+ G G P G
Sbjct: 958 GLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPGLRGIP--G 1015
Query: 502 PRGSRGNPSGGGNVQHRAGDWQCPNPGC----GNQNFAWRTECNQCKAPKPEGFLPPPFP 557
G+ G P G + PG G Q ++ P P G P
Sbjct: 1016 SMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGL 1075
Query: 558 P----PGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFG 611
P G+ G+ GP G G G G PG G+ G G GF+G +G+ G
Sbjct: 1076 PGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGL----LG 1131
Query: 612 -GGRRGGPG-----GPPGPLMEQMGGRRGGRGGPGKM-DKGE 646
G RG PG G PGP+ + G +G G PG +KGE
Sbjct: 1132 PPGIRGPPGLPGFPGSPGPM--GIRGDQGRDGIPGPAGEKGE 1171
Score = 68.2 bits (165), Expect = 2e-11
Identities = 113/409 (27%), Positives = 143/409 (34%), Gaps = 63/409 (15%)
Query: 268 RQDHPSSMGVYG-QESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGS 326
R P G++G Q G G E P G D G G+ G G +G
Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGP 1096
Query: 327 AGERGGFNKPGGPM---DEGPDLDL---------------GPPVDPDEDSDNSAIYVQGL 368
AG G PG P GP DL GPP P + ++G
Sbjct: 1097 AGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGD 1156
Query: 369 NDSVTLDDLADFFKQCGVVKMNKRT-GQPMIHIYLDKETGKP-----KGDATVSYEDPPT 422
+ A + G+++ G P + G P G + P
Sbjct: 1157 QGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQ-GAKGDRGAPGFPGLPGRKGAMGDAGPR 1215
Query: 423 AKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGL-PPREGRGMPPPLRGGPGGPGGPG 481
+E F G PP + G + P + G PP RG PG PG PG
Sbjct: 1216 GPTGIEGFPG----------------PP--GLPGAIIPGQTGNRGPPGSRGSPGAPGPPG 1257
Query: 482 GPMGRMGGRGGDRG--GFP-PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRT 538
P + G GD+G G P P+GP G+ G+ G + G P P G+ F
Sbjct: 1258 PPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRL-GAPGTPGLPGPR-GDPGFQGFP 1315
Query: 539 ECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG- 597
K GFL PP G G GP G+RG G L PG G G+ G
Sbjct: 1316 GVKGEKG--NPGFLGSIGPP--GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGM 1371
Query: 598 -GFRGGRGMDRGGFGGGRRGGPG-----GPPGPLMEQMGGRRGGRGGPG 640
G G G G RG PG G PGP E+ G +G +G PG
Sbjct: 1372 QGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEK--GNKGSKGEPG 1418
Score = 66.6 bits (161), Expect = 7e-11
Identities = 136/517 (26%), Positives = 166/517 (32%), Gaps = 84/517 (16%)
Query: 173 PQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSY 232
P PGS P P A P+ PP +P Q T G P + G G +
Sbjct: 598 PGDPGS-PGSPGPAGPAGPPGYGPQGEP--------GLQGTQGVPGAPGPPGEAGPRGEL 648
Query: 233 GQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENR 292
P PP P P G G GF GP
Sbjct: 649 SVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGP---- 704
Query: 293 SMSGPDNRGRGRGGFD--RGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGP 350
GP +G GF +G + G+ G G G G G +P M GP G
Sbjct: 705 --PGP----KGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP----GT 754
Query: 351 PVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKP- 409
P P E ++ G + + L L G ++ G P + G P
Sbjct: 755 PGFPGERGNS------GEHGEIGLPGLPGLPGTPGNEGLDGPRGDP-------GQPGPPG 801
Query: 410 -KGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVS---------LARKKPPMNSMRGGLP 459
+G E P A+ K QG + K L R P + G+P
Sbjct: 802 EQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIP 861
Query: 460 PREGRGMPPPLRGGPGGPG--GPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQH 517
+G P RG PG PG GP G G +G G G P GP G+ G P G+
Sbjct: 862 GHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFP-GAIGPPGPPGNPGTPGQRGSPGI 920
Query: 518 RAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGG 577
Q PG + Q P P GD+G G G G G
Sbjct: 921 PGVKGQRGTPGAKGE---------QGDKGNPG---PSEISHVIGDKGEPGLKGFAGNPGE 968
Query: 578 LMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGG----GRRGGPGGPPGPLMEQMGG 631
+RG PG G G G G G RG D G G G RG PG M G
Sbjct: 969 KGNRGVPGMPGLKGLKGLPGPAGPPGPRG-DLGSTGNPGEPGLRGIPGSMGNMGMPGSKG 1027
Query: 632 RRGGRGGPGKM-------------DKGEHRQERRDRP 655
+RG G PG+ DKGE RP
Sbjct: 1028 KRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRP 1064
Score = 62.4 bits (150), Expect = 1e-09
Identities = 134/517 (25%), Positives = 177/517 (34%), Gaps = 105/517 (20%)
Query: 154 STGGYNQ---PSLGYGQSNYSYPQVPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQ 210
+TG Y P + +P +PG+ P P + Q + + +
Sbjct: 113 NTGPYGLVGVPGCSGSKGEQGFPGLPGTLGY------PGIPGAAGLKGQKGAPAKEEDIE 166
Query: 211 QNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQD 270
+ G P G G G P PP + P + G
Sbjct: 167 LDAKGDPGLPGAPGPQGLPGPPGFPGPVG-PPGPPGFFGFPGAMGPRGPK-GHMGERVIG 224
Query: 271 HPSSMGVYGQESGGFSGPGENR-SMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGE 329
H GV G +G PG +++GPDNR G G +G MG G
Sbjct: 225 HKGERGVKGL-TGPPGPPGTVIVTLTGPDNR-----------TDLKGEKGDKGAMGEPGP 272
Query: 330 RGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKM 389
G PG E + G P DP GL D + F GV K
Sbjct: 273 PGPSGLPG----ESYGSEKGAPGDP------------GLQGKPGKDGVPGFPGSEGV-KG 315
Query: 390 NKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKP 449
N+ G P + + D G+ KGD PP + E++D +G + P
Sbjct: 316 NR--GFPGL-MGEDGIKGQ-KGDI-----GPPGFRGPTEYYDTYQEKGDE-----GTPGP 361
Query: 450 PMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPP-RGPRGSRGN 508
P PR RG P G PG PG PG R G RG G+P +G +G RG
Sbjct: 362 P--------GPRGARGPQGP-SGPPGVPGSPGS--SRPGLRGAP--GWPGLKGSKGERGR 408
Query: 509 PSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPP--------PG 560
P G + G +PGC +P G PP PP P
Sbjct: 409 P--GKDAMGTPG-----SPGCAG-------------SPGLPGSPGPPGPPGDIVFRKGPP 448
Query: 561 GDRGRGGPGGMRGGRGGLMDRGGPGGM-----FRGGRGGDRG--GFRGGRGMDRGGFGGG 613
GD G G G G G +G PG + + G G G G G +G+ G
Sbjct: 449 GDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAG 508
Query: 614 RRGGPGGPPGPLMEQMGGRRGGRGGPG-KMDKGEHRQ 649
+G PG P + G G +G PG K +KGE Q
Sbjct: 509 LKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQ 545
Score = 55.8 bits (133), Expect = 1e-07
Identities = 74/234 (31%), Positives = 91/234 (38%), Gaps = 63/234 (26%)
Query: 457 GLPPREG----RGMP--PPLRGGPGGPGGPG--GPMGRMG--GRGGDRG--GFP------ 498
GLP G RG+ P G PG PG PG GP G +G G G +G GFP
Sbjct: 82 GLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTL 141
Query: 499 -------PRGPRGSRGNPSGGGNVQHRA-GDWQCPNPGCGNQNFAWRTECNQCKAPKPEG 550
G +G +G P+ +++ A GD P G Q P P G
Sbjct: 142 GYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAP-GPQGL-----------PGPPG 189
Query: 551 FLPPPFPPPGGDRGRGGPGGM--RGGRGGLMDR-----------------GGPGGMFRGG 591
F P P PPG G PG M RG +G + +R G PG +
Sbjct: 190 F-PGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTL 248
Query: 592 RGGD-RGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDK 644
G D R +G +G D+G G GP G PG E G +G G PG K
Sbjct: 249 TGPDNRTDLKGEKG-DKGAMGEPGPPGPSGLPG---ESYGSEKGAPGDPGLQGK 298
Score = 52.8 bits (125), Expect = 1e-06
Identities = 55/172 (31%), Positives = 65/172 (37%), Gaps = 31/172 (18%)
Query: 447 KKPPMNSMRGGLPPREGR----GMPPPLRGGPGGPGGPG--GPMGRMGGRG--GDRGGFP 498
K PP + G P R G G+P P RG PG G PG G G G G G G
Sbjct: 1279 KGPPGTAGDMGPPGRLGAPGTPGLPGP-RGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIG 1337
Query: 499 PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPP 558
P+GP G RG+P + PG P +G PP PP
Sbjct: 1338 PKGPPGVRGDPGTLKIISLPGSPGPPGTPG----------------EPGMQGEPGPPGPP 1381
Query: 559 ----PGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRG 604
P G RG+ G G G G ++G G G G G G +G RG
Sbjct: 1382 GNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRG 1433
Score = 46.2 bits (108), Expect = 9e-05
Identities = 61/190 (32%), Positives = 76/190 (40%), Gaps = 27/190 (14%)
Query: 471 RGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNP--SGGGNVQHRAG-DWQCPNP 527
+G PG PG PG G G G P+GP+G G P +G V+ +G +P
Sbjct: 51 KGFPGPPGSPG-----QKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSP 105
Query: 528 GC----GNQNFAWRTECNQCKAPKPE-GFLPPPFPPPGGDRGRGGPGGMRGGRGG----- 577
G GN C K E GF P P G G G G++G +G
Sbjct: 106 GLPGTPGNTGPYGLVGVPGCSGSKGEQGF--PGLPGTLGYPGIPGAAGLKGQKGAPAKEE 163
Query: 578 ---LMDRGGPGGMFRGGRGGDRG--GFRG--GRGMDRGGFGGGRRGGPGGPPGPLMEQMG 630
L +G PG G G G GF G G G FG GP GP G + E++
Sbjct: 164 DIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVI 223
Query: 631 GRRGGRGGPG 640
G +G RG G
Sbjct: 224 GHKGERGVKG 233
Score = 41.2 bits (95), Expect = 0.003
Identities = 82/323 (25%), Positives = 102/323 (31%), Gaps = 66/323 (20%)
Query: 215 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 274
G P S G G Q G P +TG P + + P
Sbjct: 1143 GFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGL 1202
Query: 275 MGVYGQ--ESG--------GFSGP---------GENRSMSGPDNRGRGRGGFDRG--GMS 313
G G ++G GF GP G+ + P +RG G G
Sbjct: 1203 PGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSH 1262
Query: 314 RGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVT 373
G G +G MG G +G PG D GP LG P P QG
Sbjct: 1263 VIGIKGDKGSMGHPGPKG---PPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPG--- 1316
Query: 374 LDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGK 433
VK K + I G PKG V DP T K
Sbjct: 1317 -------------VKGEKGNPGFLGSIGPPGPIG-PKGPPGVR-GDPGTLKI-------- 1353
Query: 434 DFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG--GRG 491
+SL P + G P +G PP GP G GP GP G+ G G+
Sbjct: 1354 --------ISLPGSPGPPGT--PGEPGMQGEPGPP----GPPGNLGPCGPRGKPGKDGKP 1399
Query: 492 GDRGGFPPRGPRGSRGNPSGGGN 514
G G +G +GS+G P G+
Sbjct: 1400 GTPGPAGEKGNKGSKGEPGPAGS 1422
Score = 32.3 bits (72), Expect = 1.4
Identities = 38/125 (30%), Positives = 48/125 (38%), Gaps = 27/125 (21%)
Query: 540 CNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-- 597
C+ K K E FP P G G+ G G G G +G PG G G RG
Sbjct: 41 CDGAKGEKGE----KGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGIS 96
Query: 598 ---GFRGGRGM-----DRGGFG-------GGRRGGPGGP--PG----PLMEQMGGRRGGR 636
GF G G+ + G +G G +G G P PG P + G +G +
Sbjct: 97 GLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQK 156
Query: 637 GGPGK 641
G P K
Sbjct: 157 GAPAK 161
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.134 0.419
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,393,092
Number of Sequences: 37866
Number of extensions: 3047876
Number of successful extensions: 59212
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 589
Number of HSP's successfully gapped in prelim test: 1337
Number of HSP's that attempted gapping in prelim test: 14328
Number of HSP's gapped (non-prelim): 15553
length of query: 656
length of database: 18,247,518
effective HSP length: 109
effective length of query: 547
effective length of database: 14,120,124
effective search space: 7723707828
effective search space used: 7723707828
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.