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Search of human proteins with 4757760
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4757760 adiponectin precursor [Homo sapiens]
(244 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4757760 adiponectin precursor [Homo sapiens] 519 e-147
gi|65301115 C1q and tumor necrosis factor related protein 9 [Hom... 187 9e-48
gi|122937273 hypothetical protein LOC131149 [Homo sapiens] 186 2e-47
gi|56847616 C1q and tumor necrosis factor related protein 9B [Ho... 185 4e-47
gi|13994280 C1q and tumor necrosis factor related protein 7 isof... 167 8e-42
gi|206597454 C1q and tumor necrosis factor related protein 7 iso... 167 8e-42
gi|206597452 C1q and tumor necrosis factor related protein 7 iso... 167 8e-42
gi|94818738 C1q and tumor necrosis factor related protein 2 [Hom... 160 9e-40
gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] 160 1e-39
gi|56786155 complement component 1, q subcomponent, C chain prec... 159 3e-39
gi|166235903 complement component 1, q subcomponent, C chain pre... 159 3e-39
gi|14149712 C1q and tumor necrosis factor related protein 5 prec... 157 6e-39
gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens] 144 5e-35
gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens] 144 5e-35
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] 143 1e-34
gi|87298828 complement component 1, q subcomponent, B chain prec... 135 3e-32
gi|5729785 complement component 1, q subcomponent-like 1 [Homo s... 127 1e-29
gi|58801559 complement component 1, q subcomponent-like 3 [Homo ... 126 2e-29
gi|56606142 complement component 1, q subcomponent-like 4 [Homo ... 116 2e-26
gi|7705753 complement component 1, q subcomponent, A chain precu... 115 3e-26
gi|154937344 complement component 1, q subcomponent-like 2 [Homo... 115 3e-26
gi|13569919 C1q and tumor necrosis factor related protein 3 isof... 108 3e-24
gi|62739183 C1q and tumor necrosis factor related protein 3 isof... 108 3e-24
gi|38372917 C1q and tumor necrosis factor related protein 1 isof... 106 2e-23
gi|38372913 C1q and tumor necrosis factor related protein 1 [Hom... 106 2e-23
gi|13569944 C1q and tumor necrosis factor related protein 1 isof... 106 2e-23
gi|32967300 C1q and tumor necrosis factor related protein 6 [Hom... 99 4e-21
gi|32967294 C1q and tumor necrosis factor related protein 6 [Hom... 99 4e-21
gi|116686136 C1q and tumor necrosis factor related protein 8 [Ho... 86 4e-17
gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens] 78 6e-15
>gi|4757760 adiponectin precursor [Homo sapiens]
Length = 244
Score = 519 bits (1336), Expect = e-147
Identities = 244/244 (100%), Positives = 244/244 (100%)
Query: 1 MLLLGAVLLLLALPGHDQETTTQGPGVLLPLPKGACTGWMAGIPGHPGHNGAPGRDGRDG 60
MLLLGAVLLLLALPGHDQETTTQGPGVLLPLPKGACTGWMAGIPGHPGHNGAPGRDGRDG
Sbjct: 1 MLLLGAVLLLLALPGHDQETTTQGPGVLLPLPKGACTGWMAGIPGHPGHNGAPGRDGRDG 60
Query: 61 TPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRKGEPGEGAYVYRSAFSVGLE 120
TPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRKGEPGEGAYVYRSAFSVGLE
Sbjct: 61 TPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRKGEPGEGAYVYRSAFSVGLE 120
Query: 121 TYVTIPNMPIRFTKIFYNQQNHYDGSTGKFHCNIPGLYYFAYHITVYMKDVKVSLFKKDK 180
TYVTIPNMPIRFTKIFYNQQNHYDGSTGKFHCNIPGLYYFAYHITVYMKDVKVSLFKKDK
Sbjct: 121 TYVTIPNMPIRFTKIFYNQQNHYDGSTGKFHCNIPGLYYFAYHITVYMKDVKVSLFKKDK 180
Query: 181 AMLFTYDQYQENNVDQASGSVLLHLEVGDQVWLQVYGEGERNGLYADNDNDSTFTGFLLY 240
AMLFTYDQYQENNVDQASGSVLLHLEVGDQVWLQVYGEGERNGLYADNDNDSTFTGFLLY
Sbjct: 181 AMLFTYDQYQENNVDQASGSVLLHLEVGDQVWLQVYGEGERNGLYADNDNDSTFTGFLLY 240
Query: 241 HDTN 244
HDTN
Sbjct: 241 HDTN 244
>gi|65301115 C1q and tumor necrosis factor related protein 9 [Homo
sapiens]
Length = 333
Score = 187 bits (474), Expect = 9e-48
Identities = 99/201 (49%), Positives = 126/201 (62%), Gaps = 3/201 (1%)
Query: 42 GIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRK 101
G G G G G G G PG G G PG G G G G PG G RG+ G +G K
Sbjct: 131 GPTGPEGPRGNIGPLGPTGLPGPMGPIGKPGPKGEAGPTGPQGEPGVRGIRGWKGDRGEK 190
Query: 102 GEPGEGAYVYRSAFSVGLETYVTIPN--MPIRFTKIFYNQQNHYDGSTGKFHCNIPGLYY 159
G+ GE + +SAF+VGL P+ MPI+F KI YN+ NHYD + GKF C+I G+YY
Sbjct: 191 GKIGETLVLPKSAFTVGLTVLSKFPSSDMPIKFDKILYNEFNHYDTAAGKFTCHIAGVYY 250
Query: 160 FAYHITVYMKDVKVSLFKKDKAMLFTYDQYQENNVDQASGSVLLHLEVGDQVWLQVYGEG 219
F YHITV+ ++V+VSL K +L T D Y + DQASG ++L L++GD+VWLQV G
Sbjct: 251 FTYHITVFSRNVQVSLVKNGVKILHTKDAYMSSE-DQASGGIVLQLKLGDEVWLQVTGGE 309
Query: 220 ERNGLYADNDNDSTFTGFLLY 240
NGL+AD D+D+TFTGFLL+
Sbjct: 310 RFNGLFADEDDDTTFTGFLLF 330
Score = 77.8 bits (190), Expect = 8e-15
Identities = 41/95 (43%), Positives = 46/95 (48%), Gaps = 24/95 (25%)
Query: 36 CTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGP------------------- 76
C GIPG+PGHNG PGRDGRDG G+KG+ G+PG G
Sbjct: 23 CRQGHPGIPGNPGHNGLPGRDGRDGAKGDKGDAGEPGRPGSPGKDGTSGEKGERGADGKV 82
Query: 77 -----KGDIGETGVPGAEGPRGFPGIQGRKGEPGE 106
KGD G G PG GP+G G G KG GE
Sbjct: 83 EAKGIKGDQGSRGSPGKHGPKGLAGPMGEKGLRGE 117
>gi|122937273 hypothetical protein LOC131149 [Homo sapiens]
Length = 477
Score = 186 bits (472), Expect = 2e-47
Identities = 97/200 (48%), Positives = 122/200 (61%), Gaps = 2/200 (1%)
Query: 41 AGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGR 100
+G+ G G NG PG G G GEKGE G PGL+GP G G+ G G GP G G +G
Sbjct: 271 SGMEGKSGRNGLPGAKGDPGIKGEKGELGPPGLLGPTGPKGDIGNKGVRGPTGKKGSRGF 330
Query: 101 KGEPGEGAYVYRSAFSVGLETYVTIPNMPIRFTKIFYNQQNHYDGSTGKFHCNIPGLYYF 160
KG GE A V RSAFS GL PN+PI+F KI YN Q +Y TGKF+C+IPG Y F
Sbjct: 331 KGSKGELARVPRSAFSAGLSKPFPPPNIPIKFEKILYNDQGNYSPVTGKFNCSIPGTYVF 390
Query: 161 AYHITVYMKDVKVSLFKKDKAMLFTYDQYQENNVDQASGSVLLHLEVGDQVWLQVYGEGE 220
+YHITV + ++SL ++K + + +DQAS V+L L GDQVWL+V +
Sbjct: 391 SYHITVRGRPARISLVAQNKKQFKSRETLYGQEIDQASLLVILKLSAGDQVWLEV--SKD 448
Query: 221 RNGLYADNDNDSTFTGFLLY 240
NG+Y ++DS FTGFLLY
Sbjct: 449 WNGVYVSAEDDSIFTGFLLY 468
Score = 59.7 bits (143), Expect = 2e-09
Identities = 29/71 (40%), Positives = 39/71 (54%)
Query: 36 CTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFP 95
C G G G G+PG G G GEKGE G+ G +G KG G++G G +G +G
Sbjct: 200 CGNCTKGEKGDQGAMGSPGLHGGPGAKGEKGEMGEKGEMGDKGCCGDSGERGGKGQKGEG 259
Query: 96 GIQGRKGEPGE 106
G++G KG G+
Sbjct: 260 GMKGEKGSKGD 270
Score = 58.9 bits (141), Expect = 4e-09
Identities = 38/93 (40%), Positives = 45/93 (48%), Gaps = 6/93 (6%)
Query: 13 LPGHDQETTTQGPGVLLPLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPG 72
+PG E G P PKG GIPG PG G G G G G KGE+GD G
Sbjct: 108 VPGQKGEPGETGQ----PGPKGEAGN--LGIPGPPGVVGPQGPRGYKGEKGLKGERGDQG 161
Query: 73 LIGPKGDIGETGVPGAEGPRGFPGIQGRKGEPG 105
+ G G G G PG +G +G G+ G KG+ G
Sbjct: 162 VPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKG 194
Score = 57.8 bits (138), Expect = 9e-09
Identities = 27/70 (38%), Positives = 36/70 (51%)
Query: 36 CTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFP 95
C + +PG G G G+ G G G G G PG++GP+G G G G +G RG
Sbjct: 101 CCDCCSPVPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQ 160
Query: 96 GIQGRKGEPG 105
G+ G G+PG
Sbjct: 161 GVPGYPGKPG 170
Score = 57.0 bits (136), Expect = 1e-08
Identities = 30/66 (45%), Positives = 36/66 (54%)
Query: 42 GIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRK 101
G G G+ G PG G G G +G KG+ GL G +GD G G PG G +G PG +G K
Sbjct: 122 GPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVPGYPGKPGAQGEPGPKGDK 181
Query: 102 GEPGEG 107
G G G
Sbjct: 182 GNIGLG 187
Score = 56.2 bits (134), Expect = 2e-08
Identities = 29/71 (40%), Positives = 34/71 (47%)
Query: 36 CTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFP 95
C + G G PG G PG G G G G G G GP+G GE G+ G G +G P
Sbjct: 104 CCSPVPGQKGEPGETGQPGPKGEAGNLGIPGPPGVVGPQGPRGYKGEKGLKGERGDQGVP 163
Query: 96 GIQGRKGEPGE 106
G G+ G GE
Sbjct: 164 GYPGKPGAQGE 174
Score = 56.2 bits (134), Expect = 2e-08
Identities = 31/74 (41%), Positives = 38/74 (51%), Gaps = 9/74 (12%)
Query: 42 GIPGHPGHNGAPGRDGRDG---------TPGEKGEKGDPGLIGPKGDIGETGVPGAEGPR 92
G+PG+PG GA G G G G+KG KGD KG+ G+ G G+ G
Sbjct: 161 GVPGYPGKPGAQGEPGPKGDKGNIGLGGVKGQKGSKGDTCGNCTKGEKGDQGAMGSPGLH 220
Query: 93 GFPGIQGRKGEPGE 106
G PG +G KGE GE
Sbjct: 221 GGPGAKGEKGEMGE 234
>gi|56847616 C1q and tumor necrosis factor related protein 9B [Homo
sapiens]
Length = 333
Score = 185 bits (469), Expect = 4e-47
Identities = 98/201 (48%), Positives = 127/201 (63%), Gaps = 3/201 (1%)
Query: 42 GIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRK 101
G G G G G G G PG G G PG G G G G PG G RG+ G +G K
Sbjct: 131 GPTGPEGPRGNIGPLGPTGLPGPMGPIGKPGPKGEAGPTGPQGEPGVRGIRGWKGDRGEK 190
Query: 102 GEPGEGAYVYRSAFSVGLETYVTIPN--MPIRFTKIFYNQQNHYDGSTGKFHCNIPGLYY 159
G+ GE + +SAF+VGL P+ +PI+F KI YN+ NHYD + GKF C+I G+YY
Sbjct: 191 GKIGETLVLPKSAFTVGLTVLSKFPSSDVPIKFDKILYNEFNHYDTAVGKFTCHIAGVYY 250
Query: 160 FAYHITVYMKDVKVSLFKKDKAMLFTYDQYQENNVDQASGSVLLHLEVGDQVWLQVYGEG 219
F YHITV+ ++V+VSL K +L T D Y + DQASGS++L L++GD++WLQV G
Sbjct: 251 FTYHITVFSRNVQVSLVKNGVKILHTRDAYVSSE-DQASGSIVLQLKLGDEMWLQVTGGE 309
Query: 220 ERNGLYADNDNDSTFTGFLLY 240
NGL+AD D+D+TFTGFLL+
Sbjct: 310 RFNGLFADEDDDTTFTGFLLF 330
Score = 78.2 bits (191), Expect = 6e-15
Identities = 41/95 (43%), Positives = 46/95 (48%), Gaps = 24/95 (25%)
Query: 36 CTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGP------------------- 76
C GIPG+PGHNG PGRDGRDG G+KG+ G+PG G
Sbjct: 23 CRQGHPGIPGNPGHNGLPGRDGRDGAKGDKGDAGEPGCPGSPGKDGTSGEKGERGADGKV 82
Query: 77 -----KGDIGETGVPGAEGPRGFPGIQGRKGEPGE 106
KGD G G PG GP+G G G KG GE
Sbjct: 83 EAKGIKGDQGSRGSPGKHGPKGLAGPMGEKGLRGE 117
>gi|13994280 C1q and tumor necrosis factor related protein 7 isoform
b [Homo sapiens]
Length = 289
Score = 167 bits (423), Expect = 8e-42
Identities = 101/243 (41%), Positives = 135/243 (55%), Gaps = 35/243 (14%)
Query: 30 PLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGL---------------- 73
P P GA G PG G G PGRDGRDG GEKGEKG GL
Sbjct: 43 PGPPGA-----NGSPGPHGRIGLPGRDGRDGRKGEKGEKGTAGLRGKTGPLGLAGEKGDQ 97
Query: 74 --------IGPKGDIGETGVPGAEGPRGFPGIQGRKGEPGE---GAYVYRSAFSVGLETY 122
IGP+G+ GE G G GP+G G QG G PG G+ V +SAFSVG+ T
Sbjct: 98 GETGKKGPIGPEGEKGEVGPIGPPGPKGDRGEQGDPGLPGVCRCGSIVLKSAFSVGITTS 157
Query: 123 VTIPNMPIRFTKIFYNQQNHYDGSTGKFHCNIPGLYYFAYHITVYMKDVKVSLFKKDKAM 182
+PI F K+ +N+ HY+ +TGKF C PG+YYF+Y IT+ K + + L +
Sbjct: 158 YPEERLPIIFNKVLFNEGEHYNPATGKFICAFPGIYYFSYDITLANKHLAIGLVHNGQYR 217
Query: 183 LFTYDQYQENNVDQASGSVLLHLEVGDQVWLQVYGEGERNGLYADND-NDSTFTGFLLYH 241
+ T+D N D ASGS +++L+ D+VWL+++ ++NGL++D DS F+GFLLY
Sbjct: 218 IKTFDA-NTGNHDVASGSTVIYLQPEDEVWLEIFFT-DQNGLFSDPGWADSLFSGFLLYV 275
Query: 242 DTN 244
DT+
Sbjct: 276 DTD 278
>gi|206597454 C1q and tumor necrosis factor related protein 7
isoform b [Homo sapiens]
Length = 289
Score = 167 bits (423), Expect = 8e-42
Identities = 101/243 (41%), Positives = 135/243 (55%), Gaps = 35/243 (14%)
Query: 30 PLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGL---------------- 73
P P GA G PG G G PGRDGRDG GEKGEKG GL
Sbjct: 43 PGPPGA-----NGSPGPHGRIGLPGRDGRDGRKGEKGEKGTAGLRGKTGPLGLAGEKGDQ 97
Query: 74 --------IGPKGDIGETGVPGAEGPRGFPGIQGRKGEPGE---GAYVYRSAFSVGLETY 122
IGP+G+ GE G G GP+G G QG G PG G+ V +SAFSVG+ T
Sbjct: 98 GETGKKGPIGPEGEKGEVGPIGPPGPKGDRGEQGDPGLPGVCRCGSIVLKSAFSVGITTS 157
Query: 123 VTIPNMPIRFTKIFYNQQNHYDGSTGKFHCNIPGLYYFAYHITVYMKDVKVSLFKKDKAM 182
+PI F K+ +N+ HY+ +TGKF C PG+YYF+Y IT+ K + + L +
Sbjct: 158 YPEERLPIIFNKVLFNEGEHYNPATGKFICAFPGIYYFSYDITLANKHLAIGLVHNGQYR 217
Query: 183 LFTYDQYQENNVDQASGSVLLHLEVGDQVWLQVYGEGERNGLYADND-NDSTFTGFLLYH 241
+ T+D N D ASGS +++L+ D+VWL+++ ++NGL++D DS F+GFLLY
Sbjct: 218 IKTFDA-NTGNHDVASGSTVIYLQPEDEVWLEIFFT-DQNGLFSDPGWADSLFSGFLLYV 275
Query: 242 DTN 244
DT+
Sbjct: 276 DTD 278
>gi|206597452 C1q and tumor necrosis factor related protein 7
isoform a [Homo sapiens]
Length = 296
Score = 167 bits (423), Expect = 8e-42
Identities = 101/243 (41%), Positives = 135/243 (55%), Gaps = 35/243 (14%)
Query: 30 PLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGL---------------- 73
P P GA G PG G G PGRDGRDG GEKGEKG GL
Sbjct: 50 PGPPGA-----NGSPGPHGRIGLPGRDGRDGRKGEKGEKGTAGLRGKTGPLGLAGEKGDQ 104
Query: 74 --------IGPKGDIGETGVPGAEGPRGFPGIQGRKGEPGE---GAYVYRSAFSVGLETY 122
IGP+G+ GE G G GP+G G QG G PG G+ V +SAFSVG+ T
Sbjct: 105 GETGKKGPIGPEGEKGEVGPIGPPGPKGDRGEQGDPGLPGVCRCGSIVLKSAFSVGITTS 164
Query: 123 VTIPNMPIRFTKIFYNQQNHYDGSTGKFHCNIPGLYYFAYHITVYMKDVKVSLFKKDKAM 182
+PI F K+ +N+ HY+ +TGKF C PG+YYF+Y IT+ K + + L +
Sbjct: 165 YPEERLPIIFNKVLFNEGEHYNPATGKFICAFPGIYYFSYDITLANKHLAIGLVHNGQYR 224
Query: 183 LFTYDQYQENNVDQASGSVLLHLEVGDQVWLQVYGEGERNGLYADND-NDSTFTGFLLYH 241
+ T+D N D ASGS +++L+ D+VWL+++ ++NGL++D DS F+GFLLY
Sbjct: 225 IKTFDA-NTGNHDVASGSTVIYLQPEDEVWLEIFFT-DQNGLFSDPGWADSLFSGFLLYV 282
Query: 242 DTN 244
DT+
Sbjct: 283 DTD 285
>gi|94818738 C1q and tumor necrosis factor related protein 2 [Homo
sapiens]
Length = 330
Score = 160 bits (405), Expect = 9e-40
Identities = 105/261 (40%), Positives = 138/261 (52%), Gaps = 35/261 (13%)
Query: 5 GAVLLLLALPGHDQETTTQGPGVLLPLPKGAC--TGWMA--GIPGHPGHNG--------- 51
G+ L+ +LPG QGP P P GA +G M G PG G +G
Sbjct: 75 GSPQLVCSLPG------PQGP----PGPPGAPGPSGMMGRMGFPGKDGQDGHDGDRGDSG 124
Query: 52 ---APGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRKGEPGE-- 106
PGR G G PG KG+ G G GP+G G G PG G G G +G+KGEPG
Sbjct: 125 EEGPPGRTGNRGKPGPKGKAGAIGRAGPRGPKGVNGTPGKHGTPGKKGPKGKKGEPGLPG 184
Query: 107 ----GAYVYRSAFSVGLETYVTIPNMPIRFTKIFYNQQNHYDGSTGKFHCNIPGLYYFAY 162
G+ +SAFSV + +PI+F KI N+ HY+ S+GKF C +PG+YYF Y
Sbjct: 185 PCSCGSGHTKSAFSVAVTKSYPRERLPIKFDKILMNEGGHYNASSGKFVCGVPGIYYFTY 244
Query: 163 HITVYMKDVKVSLFKKDKAMLFTYDQYQENNVDQASGSVLLHLEVGDQVWLQVYGEGERN 222
IT+ K + + L + + T+D N D ASGS +L L+ GD+VWLQ++ E+N
Sbjct: 245 DITLANKHLAIGLVHNGQYRIRTFDA-NTGNHDVASGSTILALKQGDEVWLQIF-YSEQN 302
Query: 223 GLYADND-NDSTFTGFLLYHD 242
GL+ D DS FTGFL+Y D
Sbjct: 303 GLFYDPYWTDSLFTGFLIYAD 323
>gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]
Length = 680
Score = 160 bits (404), Expect = 1e-39
Identities = 101/255 (39%), Positives = 129/255 (50%), Gaps = 37/255 (14%)
Query: 13 LPGHDQETTTQG-PGVLLPLPKGACTGWMAGIPGHPGHNGAPGRDGRDG-----TPGEKG 66
+PGH+ E +G PG+ P +G GIPG PG G PG G G T G G
Sbjct: 432 MPGHNGEAGPRGAPGI--PGTRGPIGP--PGIPGFPGSKGDPGSPGPPGPAGIATKGLNG 487
Query: 67 EKGDPGLIGPKGDIGETGVPGAEGPRGFPG----------------------IQGRKGEP 104
G PG GP+G GE G+PG GP G PG + +G
Sbjct: 488 PTGPPGPPGPRGHSGEPGLPGPPGPPGPPGQAVMPEGFIKAGQRPSLSGTPLVSANQGVT 547
Query: 105 GEGAYVYRSAFSVGLETYVTIPNMPIRFTKIFYNQQNHYDGSTGKFHCNIPGLYYFAYHI 164
G SAF+V L PI F KI YN+Q HYD TG F C IPG+YYF+YH+
Sbjct: 548 GMPV----SAFTVILSKAYPAIGTPIPFDKILYNRQQHYDPRTGIFTCQIPGIYYFSYHV 603
Query: 165 TVYMKDVKVSLFKKDKAMLFTYDQYQENNVDQASGSVLLHLEVGDQVWLQVYGEGERNGL 224
V V V L+K +++TYD+Y + +DQASGS ++ L DQVWLQ+ E NGL
Sbjct: 604 HVKGTHVWVGLYKNGTPVMYTYDEYTKGYLDQASGSAIIDLTENDQVWLQL-PNAESNGL 662
Query: 225 YADNDNDSTFTGFLL 239
Y+ S+F+GFL+
Sbjct: 663 YSSEYVHSSFSGFLV 677
Score = 72.8 bits (177), Expect = 3e-13
Identities = 41/82 (50%), Positives = 46/82 (56%), Gaps = 4/82 (4%)
Query: 29 LPLPKGAC-TGWMAGIPGHPGHNGAPGRDGRDGTPGEKG---EKGDPGLIGPKGDIGETG 84
LP PKG AG PG G G+PG DG+ G PG+ G KG+PGL GPKGD G G
Sbjct: 357 LPGPKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVGG 416
Query: 85 VPGAEGPRGFPGIQGRKGEPGE 106
PG GP G G +G G GE
Sbjct: 417 PPGLPGPVGPAGAKGMPGHNGE 438
Score = 67.8 bits (164), Expect = 8e-12
Identities = 46/102 (45%), Positives = 49/102 (48%), Gaps = 12/102 (11%)
Query: 13 LPGHDQETTTQGPGVLLPLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDP- 71
LPG ET GP P KG G G PG+ G PG DG G PG G KGDP
Sbjct: 357 LPGPKGETGPAGPAGY-PGAKGERGS--PGSDGKPGYPGKPGLDGPKGNPGLPGPKGDPG 413
Query: 72 -----GLIGPKGDIGETGVP---GAEGPRGFPGIQGRKGEPG 105
GL GP G G G+P G GPRG PGI G +G G
Sbjct: 414 VGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIG 455
Score = 66.6 bits (161), Expect = 2e-11
Identities = 40/94 (42%), Positives = 45/94 (47%), Gaps = 3/94 (3%)
Query: 13 LPGHDQETTTQGPGVLLPLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPG 72
LPG E +GP L P AG+PG PG G PG G G G G G PG
Sbjct: 303 LPGLKGE---RGPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPG 359
Query: 73 LIGPKGDIGETGVPGAEGPRGFPGIQGRKGEPGE 106
G G G G PGA+G RG PG G+ G PG+
Sbjct: 360 PKGETGPAGPAGYPGAKGERGSPGSDGKPGYPGK 393
Score = 64.7 bits (156), Expect = 7e-11
Identities = 32/63 (50%), Positives = 36/63 (57%), Gaps = 1/63 (1%)
Query: 43 IPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRKG 102
+PG PG G G G G PGEKG G PG+ G KG++G G PG G RG PG QG G
Sbjct: 154 VPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMG-YGAPGRPGERGLPGPQGPTG 212
Query: 103 EPG 105
G
Sbjct: 213 PSG 215
Score = 64.3 bits (155), Expect = 9e-11
Identities = 31/63 (49%), Positives = 37/63 (58%), Gaps = 2/63 (3%)
Query: 42 GIPGHPGHNGAPGRD--GRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQG 99
G+ G PG G PG G+ G PG G+ G+ G GPKGD+G G+PG GP G PGI G
Sbjct: 89 GLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGPPGIPG 148
Query: 100 RKG 102
G
Sbjct: 149 PAG 151
Score = 64.3 bits (155), Expect = 9e-11
Identities = 42/96 (43%), Positives = 50/96 (52%), Gaps = 11/96 (11%)
Query: 13 LPGHDQETTTQGPGVLLPL-PKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDP 71
LPG + T PG + P PKG + G G PG G G G G PG KGE+G P
Sbjct: 330 LPG--KPGLTGPPGNMGPQGPKG-----IPGSHGLPGPKGETGPAGPAGYPGAKGERGSP 382
Query: 72 GLIGPKGDIGETGVPGAEGPRGFPGIQGRKGEPGEG 107
G G G G PG +GP+G PG+ G KG+PG G
Sbjct: 383 ---GSDGKPGYPGKPGLDGPKGNPGLPGPKGDPGVG 415
Score = 62.8 bits (151), Expect = 3e-10
Identities = 38/94 (40%), Positives = 46/94 (48%), Gaps = 4/94 (4%)
Query: 14 PGHDQETTTQGP--GVLLPLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDP 71
PG+ + GP LP PKG + G PG PG G G G G GE G +G P
Sbjct: 388 PGYPGKPGLDGPKGNPGLPGPKG--DPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAP 445
Query: 72 GLIGPKGDIGETGVPGAEGPRGFPGIQGRKGEPG 105
G+ G +G IG G+PG G +G PG G G G
Sbjct: 446 GIPGTRGPIGPPGIPGFPGSKGDPGSPGPPGPAG 479
Score = 62.4 bits (150), Expect = 3e-10
Identities = 43/112 (38%), Positives = 50/112 (44%), Gaps = 21/112 (18%)
Query: 14 PGHDQETTTQGPGVLLPLPKGACTGWMAGIPGHPGHNGAPGRDGR---DGTPGEKGEKGD 70
PG E GP P P + G+PG PG G G G G PG +G G
Sbjct: 88 PGLQGEPGLPGP----PGPSAVGKPGVPGLPGKPGERGPYGPKGDVGPAGLPGPRGPPGP 143
Query: 71 PGLIGPKG-----DIGETGVPGAEGPRGFPG---------IQGRKGEPGEGA 108
PG+ GP G G+ G GA GPRGFPG + G+KGE G GA
Sbjct: 144 PGIPGPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGA 195
Score = 60.1 bits (144), Expect = 2e-09
Identities = 37/101 (36%), Positives = 44/101 (43%), Gaps = 5/101 (4%)
Query: 14 PGHDQETTTQG----PGVLLPL-PKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEK 68
PG T+G PG+ P P G + G+ G G G PG G G G G
Sbjct: 272 PGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQGPAGLP 331
Query: 69 GDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRKGEPGEGAY 109
G PGL GP G++G G G G G PG +G G G Y
Sbjct: 332 GKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPAGY 372
Score = 59.3 bits (142), Expect = 3e-09
Identities = 33/83 (39%), Positives = 38/83 (45%), Gaps = 19/83 (22%)
Query: 42 GIPGHPGHNGAPG-----------------RDGRDGTPGEKGEKGDPGLIGPKGDIGETG 84
G PG PG G PG +G G PG KG++G PG +GP G G G
Sbjct: 194 GAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQG 253
Query: 85 VPGAEGPRGF--PGIQGRKGEPG 105
PG GP G PG G G+PG
Sbjct: 254 PPGERGPEGIGKPGAAGAPGQPG 276
Score = 57.4 bits (137), Expect = 1e-08
Identities = 40/104 (38%), Positives = 46/104 (44%), Gaps = 10/104 (9%)
Query: 14 PGHDQETTTQGP-GVLLPL-PKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDP 71
PG E GP G P P G G+PG PG G G G G G G +G P
Sbjct: 196 PGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGIKGDRGFPGEMGPIGPPGPQGPP 255
Query: 72 GLIGPKG--------DIGETGVPGAEGPRGFPGIQGRKGEPGEG 107
G GP+G G+ G+PG +G G PGI G G PG G
Sbjct: 256 GERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFG 299
Score = 56.6 bits (135), Expect = 2e-08
Identities = 31/65 (47%), Positives = 35/65 (53%), Gaps = 4/65 (6%)
Query: 45 GHPGHNGAPGRDGRDGT--PGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGF--PGIQGR 100
G PG G PG G +G PG G G PG+ G KG G G+ G GP GF PG+ G
Sbjct: 247 GPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGL 306
Query: 101 KGEPG 105
KGE G
Sbjct: 307 KGERG 311
Score = 56.2 bits (134), Expect = 2e-08
Identities = 33/82 (40%), Positives = 39/82 (47%), Gaps = 18/82 (21%)
Query: 42 GIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPR--------- 92
G G PG G PG G G PG G+KG+ G G G GE G+PG +GP
Sbjct: 162 GPTGAPGPRGFPGEKGAPGVPGMNGQKGEMG-YGAPGRPGERGLPGPQGPTGPSGPPGVG 220
Query: 93 --------GFPGIQGRKGEPGE 106
G PGI+G +G PGE
Sbjct: 221 KRGENGVPGQPGIKGDRGFPGE 242
Score = 55.1 bits (131), Expect = 6e-08
Identities = 30/69 (43%), Positives = 34/69 (49%), Gaps = 5/69 (7%)
Query: 42 GIPGHPGHNGAPGRDGRDGTPGEKGEK-----GDPGLIGPKGDIGETGVPGAEGPRGFPG 96
G G PG G PG G G PG G G PGL G KG+ G G+PG G +G G
Sbjct: 267 GAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGKPGLPGLKGERGPAGLPGGPGAKGEQG 326
Query: 97 IQGRKGEPG 105
G G+PG
Sbjct: 327 PAGLPGKPG 335
Score = 54.7 bits (130), Expect = 7e-08
Identities = 33/80 (41%), Positives = 39/80 (48%), Gaps = 7/80 (8%)
Query: 33 KGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGE-----KGDPGLIGPKGD--IGETGV 85
KG G PG PG G G G G PG+ G +G+PGL GP G +G+ GV
Sbjct: 51 KGIAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGV 110
Query: 86 PGAEGPRGFPGIQGRKGEPG 105
PG G G G G KG+ G
Sbjct: 111 PGLPGKPGERGPYGPKGDVG 130
Score = 48.5 bits (114), Expect = 5e-06
Identities = 27/63 (42%), Positives = 31/63 (49%), Gaps = 10/63 (15%)
Query: 54 GRDGRDGTPGEKGEKGDPGLIGPKGD--------IGETGVPGAEGPR--GFPGIQGRKGE 103
G G G PG G +G PG GP G GE G+PG GP G PG+ G G+
Sbjct: 57 GEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKPGVPGLPGK 116
Query: 104 PGE 106
PGE
Sbjct: 117 PGE 119
Score = 38.9 bits (89), Expect = 0.004
Identities = 17/35 (48%), Positives = 21/35 (60%)
Query: 74 IGPKGDIGETGVPGAEGPRGFPGIQGRKGEPGEGA 108
I +G+ G G PG GPRG PG G G+PG G+
Sbjct: 53 IAVRGEQGTPGPPGPAGPRGHPGPSGPPGKPGYGS 87
>gi|56786155 complement component 1, q subcomponent, C chain
precursor [Homo sapiens]
Length = 245
Score = 159 bits (401), Expect = 3e-39
Identities = 104/233 (44%), Positives = 133/233 (57%), Gaps = 24/233 (10%)
Query: 27 VLLPLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKG---DPGLIGPKGDIGET 83
+LLPL A TG GIPG PG GAPG+DG DG PG KGE G PG+ GPKG GE
Sbjct: 20 LLLPLRGQANTGCY-GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEP 78
Query: 84 GVP------GAEGPRGFPGIQGRKGEPG----EGAY--VYRSAFSVGLETY-VTIPNMPI 130
G+P G GP G PG+ G G PG EG Y ++S F+V +T+ PN I
Sbjct: 79 GLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVFTVTRQTHQPPAPNSLI 138
Query: 131 RFTKIFYNQQNHYDGSTGKFHCNIPGLYYFAYHITVYMKDVKVSLFKKD-KAMLFTYDQY 189
RF + N Q YD STGKF C +PGLYYF YH + + ++ V L++ K + F
Sbjct: 139 RFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHAS-HTANLCVLLYRSGVKVVTFCGHTS 197
Query: 190 QENNVDQASGSVLLHLEVGDQVWLQVYGEGERNGLYADNDNDSTFTGFLLYHD 242
+ N V+ SG VLL L+VG++VWL V + G+ +DS F+GFLL+ D
Sbjct: 198 KTNQVN--SGGVLLRLQVGEEVWLAVNDYYDMVGI---QGSDSVFSGFLLFPD 245
>gi|166235903 complement component 1, q subcomponent, C chain
precursor [Homo sapiens]
Length = 245
Score = 159 bits (401), Expect = 3e-39
Identities = 104/233 (44%), Positives = 133/233 (57%), Gaps = 24/233 (10%)
Query: 27 VLLPLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKG---DPGLIGPKGDIGET 83
+LLPL A TG GIPG PG GAPG+DG DG PG KGE G PG+ GPKG GE
Sbjct: 20 LLLPLRGQANTGCY-GIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEP 78
Query: 84 GVP------GAEGPRGFPGIQGRKGEPG----EGAY--VYRSAFSVGLETY-VTIPNMPI 130
G+P G GP G PG+ G G PG EG Y ++S F+V +T+ PN I
Sbjct: 79 GLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVFTVTRQTHQPPAPNSLI 138
Query: 131 RFTKIFYNQQNHYDGSTGKFHCNIPGLYYFAYHITVYMKDVKVSLFKKD-KAMLFTYDQY 189
RF + N Q YD STGKF C +PGLYYF YH + + ++ V L++ K + F
Sbjct: 139 RFNAVLTNPQGDYDTSTGKFTCKVPGLYYFVYHAS-HTANLCVLLYRSGVKVVTFCGHTS 197
Query: 190 QENNVDQASGSVLLHLEVGDQVWLQVYGEGERNGLYADNDNDSTFTGFLLYHD 242
+ N V+ SG VLL L+VG++VWL V + G+ +DS F+GFLL+ D
Sbjct: 198 KTNQVN--SGGVLLRLQVGEEVWLAVNDYYDMVGI---QGSDSVFSGFLLFPD 245
>gi|14149712 C1q and tumor necrosis factor related protein 5
precursor [Homo sapiens]
Length = 243
Score = 157 bits (398), Expect = 6e-39
Identities = 93/212 (43%), Positives = 118/212 (55%), Gaps = 19/212 (8%)
Query: 40 MAGIPGHPGHNGAPGRDGRD------GTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRG 93
+ G PGH G G PGRDGRD G PGEKGE G PGL GP+GD GPRG
Sbjct: 34 LPGTPGHHGSQGLPGRDGRDGRDGAPGAPGEKGEGGRPGLPGPRGD---------PGPRG 84
Query: 94 FPGIQGRKGEPGEGAYVYRSAFSV-GLETYVTIP-NMPIRFTKIFYNQQNHYDGSTGKFH 151
G G G GE + RSAFS E+ V P + P+ F ++ N+Q HYD TGKF
Sbjct: 85 EAGPAGPTGPAGECSVPPRSAFSAKRSESRVPPPSDAPLPFDRVLVNEQGHYDAVTGKFT 144
Query: 152 CNIPGLYYFAYHITVYMKDVKVSLFKKDKAMLFTYDQYQE-NNVDQASGSVLLHLEVGDQ 210
C +PG+YYFA H TVY ++ L K +++ + + SG ++ LE DQ
Sbjct: 145 CQVPGVYYFAVHATVYRASLQFDLVKNGESIASFFQFFGGWPKPASLSGGAMVRLEPEDQ 204
Query: 211 VWLQVYGEGERNGLYADNDNDSTFTGFLLYHD 242
VW+QV G G+ G+YA DSTF+GFL+Y D
Sbjct: 205 VWVQV-GVGDYIGIYASIKTDSTFSGFLVYSD 235
>gi|32895368 alpha 1 type VIII collagen precursor [Homo sapiens]
Length = 744
Score = 144 bits (364), Expect = 5e-35
Identities = 96/269 (35%), Positives = 134/269 (49%), Gaps = 55/269 (20%)
Query: 25 PGVLLPLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKG--DIGE 82
PG+L P + G G+ G PG G G G G PG G KG+PGL GP G IG+
Sbjct: 476 PGLLGPKGEPGIPGDQ-GLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGK 534
Query: 83 TGV---------PGAEGPRGFPGIQGRKGEPG--------------EGAYV--------- 110
GV PGA GP+G PG+ G G PG +G Y+
Sbjct: 535 PGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDG 594
Query: 111 -------------------YRSAFSVGLETYVTIPNMPIRFTKIFYNQQNHYDGSTGKFH 151
AF+ L P++F K+ YN + +Y+ TG F
Sbjct: 595 VKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNGRQNYNPQTGIFT 654
Query: 152 CNIPGLYYFAYHITVYMKDVKVSLFKKDKAMLFTYDQYQENNVDQASGSVLLHLEVGDQV 211
C +PG+YYFAYH+ +V V+LFK ++ +++TYD+Y++ +DQASGS +L L GD+V
Sbjct: 655 CEVPGVYYFAYHVHCKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRV 714
Query: 212 WLQVYGEGERNGLYADNDNDSTFTGFLLY 240
+LQ+ E + GLYA S+F+G+LLY
Sbjct: 715 FLQMPSE-QAAGLYAGQYVHSSFSGYLLY 742
Score = 69.7 bits (169), Expect = 2e-12
Identities = 42/88 (47%), Positives = 48/88 (54%), Gaps = 12/88 (13%)
Query: 25 PGVL-LPLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGL------IGPK 77
PG + P PKG G + G G PG G PG G G PG GE G PG+ IGPK
Sbjct: 404 PGAIGFPGPKGE--GGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPK 461
Query: 78 GDIGETGVPGAEGPRGFPGIQGRKGEPG 105
G+ G+ GVPG G PG+ G KGEPG
Sbjct: 462 GEAGQKGVPGLP---GVPGLLGPKGEPG 486
Score = 65.1 bits (157), Expect = 5e-11
Identities = 34/76 (44%), Positives = 41/76 (53%), Gaps = 2/76 (2%)
Query: 32 PKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGP 91
PKG G+PG PG G G G G PG++G +G PG+ G G G G PG GP
Sbjct: 460 PKGEAG--QKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGP 517
Query: 92 RGFPGIQGRKGEPGEG 107
+G PG+ G G PG G
Sbjct: 518 KGEPGLPGPPGFPGIG 533
Score = 63.5 bits (153), Expect = 2e-10
Identities = 43/108 (39%), Positives = 48/108 (44%), Gaps = 16/108 (14%)
Query: 10 LLALPGHDQETTTQGPGVLLPLPKGACTGWMAGIPGH------------PGHNGAPGRDG 57
L LPG PG P PKG M G+PG PG G PG G
Sbjct: 338 LPGLPGPPGLPGIGKPG--FPGPKG--DRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPG 393
Query: 58 RDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRKGEPG 105
G PG G G G GPKG+ G G G GP+G PG+QG G+PG
Sbjct: 394 LPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPG 441
Score = 62.4 bits (150), Expect = 3e-10
Identities = 44/103 (42%), Positives = 49/103 (47%), Gaps = 9/103 (8%)
Query: 13 LPGHDQETTTQGPGVL-----LPLPKGACTGWMAGIPG---HPGHNGAPGRDGRDGTPGE 64
LPG +GP L L PKG M G PG PG +G PG G G G+
Sbjct: 215 LPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGV-GK 273
Query: 65 KGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRKGEPGEG 107
G G PG GP G G G PG +GP G PG+QG G PG G
Sbjct: 274 PGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIG 316
Score = 62.0 bits (149), Expect = 5e-10
Identities = 38/84 (45%), Positives = 45/84 (53%), Gaps = 9/84 (10%)
Query: 30 PLPKGACTGWMAGIPGHPGHNGAPG--RDGRDGTPGEKGEKGDPGL---IGPKGDIGETG 84
P P G + GI G PG G PG + G G PG+ G G PG IG KG+IG G
Sbjct: 132 PGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMG 191
Query: 85 VPGAE---GPRGFPGIQGRKGEPG 105
+PG + GP G PGI G+ G PG
Sbjct: 192 IPGPQGPPGPHGLPGI-GKPGGPG 214
Score = 62.0 bits (149), Expect = 5e-10
Identities = 40/114 (35%), Positives = 50/114 (43%), Gaps = 22/114 (19%)
Query: 13 LPGHDQETTTQGPGVLLPLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPG 72
LPGH PG P+G G+PG PG GA G G G G+KGE G G
Sbjct: 137 LPGHGIPGIKGKPG-----PQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMG 191
Query: 73 LIGPKGDIGETGVPGA-----------------EGPRGFPGIQGRKGEPGEGAY 109
+ GP+G G G+PG GP+G PG QG +G G+ +
Sbjct: 192 IPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGF 245
Score = 62.0 bits (149), Expect = 5e-10
Identities = 35/83 (42%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Query: 25 PGVLLPLPKGACTG--WMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGE 82
PG L P + G + G PG PG G PG G G G G KG+ G++GP+G G
Sbjct: 368 PGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGP 427
Query: 83 TGVPGAEGPRGFPGIQGRKGEPG 105
G PG +G G PG G G PG
Sbjct: 428 KGEPGLQGFPGKPGFLGEVGPPG 450
Score = 60.5 bits (145), Expect = 1e-09
Identities = 41/97 (42%), Positives = 47/97 (48%), Gaps = 7/97 (7%)
Query: 11 LALPGHDQETTTQGPGVLLPLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPG--EKGEK 68
+ LPG + T PG PL K G PG G G PG G G PG + G+
Sbjct: 266 VGLPGVGKPGVTGFPGPQGPLGKPGAPGE----PGPQGPIGVPGVQGPPGIPGIGKPGQD 321
Query: 69 GDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRKGEPG 105
G PG G G GE G+PG GP G PGI G+ G PG
Sbjct: 322 GIPGQPGFPGGKGEQGLPGLPGPPGLPGI-GKPGFPG 357
Score = 60.5 bits (145), Expect = 1e-09
Identities = 36/84 (42%), Positives = 44/84 (52%), Gaps = 16/84 (19%)
Query: 42 GIPGHPGHNGAPGRDGRDGTPGEKGEKGD---PGLIGPKGDIG------------ETGVP 86
G+PG PG G PG G+ G PG KG++G PG +GP+G+ G E G+P
Sbjct: 337 GLPGLPGPPGLPGI-GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLP 395
Query: 87 GAEGPRGFPGIQGRKGEPGEGAYV 110
G GP G PG G G GEG V
Sbjct: 396 GIPGPMGPPGAIGFPGPKGEGGIV 419
Score = 59.7 bits (143), Expect = 2e-09
Identities = 39/101 (38%), Positives = 47/101 (46%), Gaps = 4/101 (3%)
Query: 11 LALPGHDQETTTQGPGVLLPLPKGACTGWMAGIPG--HPGHNGAPGRDGRDGTPGEKGEK 68
+ +PG E +G + +P G+PG PG G PG+ G G G KG
Sbjct: 172 MGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLP 231
Query: 69 GDPGLIGPKGD--IGETGVPGAEGPRGFPGIQGRKGEPGEG 107
G GL GPKGD G G PG +GP G G G G PG G
Sbjct: 232 GPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVG 272
Score = 57.4 bits (137), Expect = 1e-08
Identities = 36/88 (40%), Positives = 44/88 (50%), Gaps = 4/88 (4%)
Query: 24 GPGVLLPLPKGACTGWMA--GIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGL--IGPKGD 79
GP L + K TG+ G G PG G PG G G PG +G G PG+ G G
Sbjct: 264 GPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGI 323
Query: 80 IGETGVPGAEGPRGFPGIQGRKGEPGEG 107
G+ G PG +G +G PG+ G G PG G
Sbjct: 324 PGQPGFPGGKGEQGLPGLPGPPGLPGIG 351
Score = 48.1 bits (113), Expect = 7e-06
Identities = 29/72 (40%), Positives = 36/72 (50%), Gaps = 6/72 (8%)
Query: 40 MAGIPGHPGHNGAPGRDGRDGTPGEKGE-----KGDPGLIGPKGDIGETGVPGAEGPRGF 94
+A + G G G PG G G PG G KG PG G G +G+ G+PG G G
Sbjct: 113 LASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPG-VGKPGMPGMPGKPGA 171
Query: 95 PGIQGRKGEPGE 106
G+ G KGE G+
Sbjct: 172 MGMPGAKGEIGQ 183
Score = 37.7 bits (86), Expect = 0.009
Identities = 23/57 (40%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
Query: 55 RDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFP--GIQGRKGEPGEGAY 109
R G++ P + E L G +G GE G G GP G P GI G KG+PG Y
Sbjct: 98 RMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGY 154
>gi|17738302 alpha 1 type VIII collagen precursor [Homo sapiens]
Length = 744
Score = 144 bits (364), Expect = 5e-35
Identities = 96/269 (35%), Positives = 134/269 (49%), Gaps = 55/269 (20%)
Query: 25 PGVLLPLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKG--DIGE 82
PG+L P + G G+ G PG G G G G PG G KG+PGL GP G IG+
Sbjct: 476 PGLLGPKGEPGIPGDQ-GLQGPPGIPGIGGPSGPIGPPGIPGPKGEPGLPGPPGFPGIGK 534
Query: 83 TGV---------PGAEGPRGFPGIQGRKGEPG--------------EGAYV--------- 110
GV PGA GP+G PG+ G G PG +G Y+
Sbjct: 535 PGVAGLHGPPGKPGALGPQGQPGLPGPPGPPGPPGPPAVMPPTPPPQGEYLPDMGLGIDG 594
Query: 111 -------------------YRSAFSVGLETYVTIPNMPIRFTKIFYNQQNHYDGSTGKFH 151
AF+ L P++F K+ YN + +Y+ TG F
Sbjct: 595 VKPPHAYGAKKGKNGGPAYEMPAFTAELTAPFPPVGAPVKFNKLLYNGRQNYNPQTGIFT 654
Query: 152 CNIPGLYYFAYHITVYMKDVKVSLFKKDKAMLFTYDQYQENNVDQASGSVLLHLEVGDQV 211
C +PG+YYFAYH+ +V V+LFK ++ +++TYD+Y++ +DQASGS +L L GD+V
Sbjct: 655 CEVPGVYYFAYHVHCKGGNVWVALFKNNEPVMYTYDEYKKGFLDQASGSAVLLLRPGDRV 714
Query: 212 WLQVYGEGERNGLYADNDNDSTFTGFLLY 240
+LQ+ E + GLYA S+F+G+LLY
Sbjct: 715 FLQMPSE-QAAGLYAGQYVHSSFSGYLLY 742
Score = 69.7 bits (169), Expect = 2e-12
Identities = 42/88 (47%), Positives = 48/88 (54%), Gaps = 12/88 (13%)
Query: 25 PGVL-LPLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGL------IGPK 77
PG + P PKG G + G G PG G PG G G PG GE G PG+ IGPK
Sbjct: 404 PGAIGFPGPKGE--GGIVGPQGPPGPKGEPGLQGFPGKPGFLGEVGPPGMRGLPGPIGPK 461
Query: 78 GDIGETGVPGAEGPRGFPGIQGRKGEPG 105
G+ G+ GVPG G PG+ G KGEPG
Sbjct: 462 GEAGQKGVPGLP---GVPGLLGPKGEPG 486
Score = 65.1 bits (157), Expect = 5e-11
Identities = 34/76 (44%), Positives = 41/76 (53%), Gaps = 2/76 (2%)
Query: 32 PKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGP 91
PKG G+PG PG G G G G PG++G +G PG+ G G G G PG GP
Sbjct: 460 PKGEAG--QKGVPGLPGVPGLLGPKGEPGIPGDQGLQGPPGIPGIGGPSGPIGPPGIPGP 517
Query: 92 RGFPGIQGRKGEPGEG 107
+G PG+ G G PG G
Sbjct: 518 KGEPGLPGPPGFPGIG 533
Score = 63.5 bits (153), Expect = 2e-10
Identities = 43/108 (39%), Positives = 48/108 (44%), Gaps = 16/108 (14%)
Query: 10 LLALPGHDQETTTQGPGVLLPLPKGACTGWMAGIPGH------------PGHNGAPGRDG 57
L LPG PG P PKG M G+PG PG G PG G
Sbjct: 338 LPGLPGPPGLPGIGKPG--FPGPKG--DRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPG 393
Query: 58 RDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRKGEPG 105
G PG G G G GPKG+ G G G GP+G PG+QG G+PG
Sbjct: 394 LPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGPKGEPGLQGFPGKPG 441
Score = 62.4 bits (150), Expect = 3e-10
Identities = 44/103 (42%), Positives = 49/103 (47%), Gaps = 9/103 (8%)
Query: 13 LPGHDQETTTQGPGVL-----LPLPKGACTGWMAGIPG---HPGHNGAPGRDGRDGTPGE 64
LPG +GP L L PKG M G PG PG +G PG G G G+
Sbjct: 215 LPGQPGPKGDRGPKGLPGPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGV-GK 273
Query: 65 KGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRKGEPGEG 107
G G PG GP G G G PG +GP G PG+QG G PG G
Sbjct: 274 PGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIG 316
Score = 62.0 bits (149), Expect = 5e-10
Identities = 38/84 (45%), Positives = 45/84 (53%), Gaps = 9/84 (10%)
Query: 30 PLPKGACTGWMAGIPGHPGHNGAPG--RDGRDGTPGEKGEKGDPGL---IGPKGDIGETG 84
P P G + GI G PG G PG + G G PG+ G G PG IG KG+IG G
Sbjct: 132 PGPPGLPGHGIPGIKGKPGPQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMG 191
Query: 85 VPGAE---GPRGFPGIQGRKGEPG 105
+PG + GP G PGI G+ G PG
Sbjct: 192 IPGPQGPPGPHGLPGI-GKPGGPG 214
Score = 62.0 bits (149), Expect = 5e-10
Identities = 40/114 (35%), Positives = 50/114 (43%), Gaps = 22/114 (19%)
Query: 13 LPGHDQETTTQGPGVLLPLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPG 72
LPGH PG P+G G+PG PG GA G G G G+KGE G G
Sbjct: 137 LPGHGIPGIKGKPG-----PQGYPGVGKPGMPGMPGKPGAMGMPGAKGEIGQKGEIGPMG 191
Query: 73 LIGPKGDIGETGVPGA-----------------EGPRGFPGIQGRKGEPGEGAY 109
+ GP+G G G+PG GP+G PG QG +G G+ +
Sbjct: 192 IPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLPGPQGLRGPKGDKGF 245
Score = 62.0 bits (149), Expect = 5e-10
Identities = 35/83 (42%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Query: 25 PGVLLPLPKGACTG--WMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGE 82
PG L P + G + G PG PG G PG G G G G KG+ G++GP+G G
Sbjct: 368 PGALGPRGEKGPIGAPGIGGPPGEPGLPGIPGPMGPPGAIGFPGPKGEGGIVGPQGPPGP 427
Query: 83 TGVPGAEGPRGFPGIQGRKGEPG 105
G PG +G G PG G G PG
Sbjct: 428 KGEPGLQGFPGKPGFLGEVGPPG 450
Score = 60.5 bits (145), Expect = 1e-09
Identities = 41/97 (42%), Positives = 47/97 (48%), Gaps = 7/97 (7%)
Query: 11 LALPGHDQETTTQGPGVLLPLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPG--EKGEK 68
+ LPG + T PG PL K G PG G G PG G G PG + G+
Sbjct: 266 VGLPGVGKPGVTGFPGPQGPLGKPGAPGE----PGPQGPIGVPGVQGPPGIPGIGKPGQD 321
Query: 69 GDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRKGEPG 105
G PG G G GE G+PG GP G PGI G+ G PG
Sbjct: 322 GIPGQPGFPGGKGEQGLPGLPGPPGLPGI-GKPGFPG 357
Score = 60.5 bits (145), Expect = 1e-09
Identities = 36/84 (42%), Positives = 44/84 (52%), Gaps = 16/84 (19%)
Query: 42 GIPGHPGHNGAPGRDGRDGTPGEKGEKGD---PGLIGPKGDIG------------ETGVP 86
G+PG PG G PG G+ G PG KG++G PG +GP+G+ G E G+P
Sbjct: 337 GLPGLPGPPGLPGI-GKPGFPGPKGDRGMGGVPGALGPRGEKGPIGAPGIGGPPGEPGLP 395
Query: 87 GAEGPRGFPGIQGRKGEPGEGAYV 110
G GP G PG G G GEG V
Sbjct: 396 GIPGPMGPPGAIGFPGPKGEGGIV 419
Score = 59.7 bits (143), Expect = 2e-09
Identities = 39/101 (38%), Positives = 47/101 (46%), Gaps = 4/101 (3%)
Query: 11 LALPGHDQETTTQGPGVLLPLPKGACTGWMAGIPG--HPGHNGAPGRDGRDGTPGEKGEK 68
+ +PG E +G + +P G+PG PG G PG+ G G G KG
Sbjct: 172 MGMPGAKGEIGQKGEIGPMGIPGPQGPPGPHGLPGIGKPGGPGLPGQPGPKGDRGPKGLP 231
Query: 69 GDPGLIGPKGD--IGETGVPGAEGPRGFPGIQGRKGEPGEG 107
G GL GPKGD G G PG +GP G G G G PG G
Sbjct: 232 GPQGLRGPKGDKGFGMPGAPGVKGPPGMHGPPGPVGLPGVG 272
Score = 57.4 bits (137), Expect = 1e-08
Identities = 36/88 (40%), Positives = 44/88 (50%), Gaps = 4/88 (4%)
Query: 24 GPGVLLPLPKGACTGWMA--GIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGL--IGPKGD 79
GP L + K TG+ G G PG G PG G G PG +G G PG+ G G
Sbjct: 264 GPVGLPGVGKPGVTGFPGPQGPLGKPGAPGEPGPQGPIGVPGVQGPPGIPGIGKPGQDGI 323
Query: 80 IGETGVPGAEGPRGFPGIQGRKGEPGEG 107
G+ G PG +G +G PG+ G G PG G
Sbjct: 324 PGQPGFPGGKGEQGLPGLPGPPGLPGIG 351
Score = 48.1 bits (113), Expect = 7e-06
Identities = 29/72 (40%), Positives = 36/72 (50%), Gaps = 6/72 (8%)
Query: 40 MAGIPGHPGHNGAPGRDGRDGTPGEKGE-----KGDPGLIGPKGDIGETGVPGAEGPRGF 94
+A + G G G PG G G PG G KG PG G G +G+ G+PG G G
Sbjct: 113 LASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGYPG-VGKPGMPGMPGKPGA 171
Query: 95 PGIQGRKGEPGE 106
G+ G KGE G+
Sbjct: 172 MGMPGAKGEIGQ 183
Score = 37.7 bits (86), Expect = 0.009
Identities = 23/57 (40%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
Query: 55 RDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFP--GIQGRKGEPGEGAY 109
R G++ P + E L G +G GE G G GP G P GI G KG+PG Y
Sbjct: 98 RMGKEAVPKKGKEIPLASLRGEQGPRGEPGPRGPPGPPGLPGHGIPGIKGKPGPQGY 154
>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
Length = 703
Score = 143 bits (361), Expect = 1e-34
Identities = 92/254 (36%), Positives = 129/254 (50%), Gaps = 28/254 (11%)
Query: 11 LALPGHDQETTTQG-PGVLLPLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKG 69
L LPG G PG+ P G + G+ G PG G PG +GR G PG G G
Sbjct: 450 LGLPGQPGLRGPSGIPGLQGPAGPIGPQG-LPGLKGEPGLPGPPG-EGRAGEPGTAGPTG 507
Query: 70 DPGLIGPKGDIGETGVPGAEGPRGFPG--------------------IQGRKGEP----G 105
PG+ G G G G PG GP G PG + G+ G+P G
Sbjct: 508 PPGVPGSPGITGPPGPPGPPGPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGLG 567
Query: 106 EGAYVYRSAFSVGLETYVTIPNMPIRFTKIFYNQQNHYDGSTGKFHCNIPGLYYFAYHIT 165
E + AF+ L + MP++F + YN + Y+ +TG F C + G+YYFAYH+
Sbjct: 568 ELSAHATPAFTAVLTSPFPASGMPVKFDRTLYNGHSGYNPATGIFTCPVGGVYYFAYHVH 627
Query: 166 VYMKDVKVSLFKKDKAMLFTYDQYQENNVDQASGSVLLHLEVGDQVWLQVYGEGERNGLY 225
V +V V+L+K + +TYD+Y++ +DQASG +L L DQVW+Q+ + + NGLY
Sbjct: 628 VKGTNVWVALYKNNVPATYTYDEYKKGYLDQASGGAVLQLRPNDQVWVQMPSD-QANGLY 686
Query: 226 ADNDNDSTFTGFLL 239
+ S+F+GFLL
Sbjct: 687 STEYIHSSFSGFLL 700
Score = 69.3 bits (168), Expect = 3e-12
Identities = 41/92 (44%), Positives = 47/92 (51%), Gaps = 3/92 (3%)
Query: 14 PGHDQETTTQGPGVLLPLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGL 73
PG D E QGP L P + + G G PG G G G G PG +G++G GL
Sbjct: 342 PGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSGL 401
Query: 74 IGPKGDIGETGVPGAEGPRGFPGIQGRKGEPG 105
G G GE G+PGA GP PG G KGEPG
Sbjct: 402 AGKPGVPGERGLPGAHGP---PGPTGPKGEPG 430
Score = 68.6 bits (166), Expect = 5e-12
Identities = 40/91 (43%), Positives = 47/91 (51%), Gaps = 13/91 (14%)
Query: 24 GP-GVLLPLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGD-----PGLIGPK 77
GP G+ +P GA G+PG PG G PG G G PG++G KGD PGL G
Sbjct: 165 GPSGITIPGKPGA-----QGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLPGAP 219
Query: 78 GDIGETGVPGAEGPRGF--PGIQGRKGEPGE 106
G G G PG GP G PG+ G G PG+
Sbjct: 220 GQGGAPGPPGLPGPAGLGKPGLDGLPGAPGD 250
Score = 66.6 bits (161), Expect = 2e-11
Identities = 40/88 (45%), Positives = 44/88 (50%), Gaps = 13/88 (14%)
Query: 31 LPKGACTGWMAGIPGHPGHNGA--PGRDGRDGTPGEKGEKGDPGLIGPKGDIGE------ 82
LP G G PG PG G PG DG G PG+KGE G PG+ GP+G+ G
Sbjct: 215 LPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPKGP 274
Query: 83 -----TGVPGAEGPRGFPGIQGRKGEPG 105
GVPGA G G G G KGEPG
Sbjct: 275 PGVDGVGVPGAAGLPGPQGPSGAKGEPG 302
Score = 66.2 bits (160), Expect = 2e-11
Identities = 45/103 (43%), Positives = 52/103 (50%), Gaps = 11/103 (10%)
Query: 13 LPGHDQETTTQGP-GVLLPLPKGACTGWMAGIPGH-----PGHNGAPGRDGRDGTPGEKG 66
LPG + GP GV P + G G PG PG G PG G G GE G
Sbjct: 244 LPGAPGDKGESGPPGVPGPRGEPGAVG-PKGPPGVDGVGVPGAAGLPGPQGPSGAKGEPG 302
Query: 67 EKGDPGLIGPKGDIGETGVPGAE---GPRGFPGIQGRKGEPGE 106
+G PGLIGP G G G+PG + GP G PG+ G +GEPGE
Sbjct: 303 TRGPPGLIGPTG-YGMPGLPGPKGDRGPAGVPGLLGDRGEPGE 344
Score = 65.5 bits (158), Expect = 4e-11
Identities = 38/81 (46%), Positives = 42/81 (51%), Gaps = 8/81 (9%)
Query: 29 LPLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGD--IGETGVP 86
LP P G IPG PG G PG G G PG +GE G PG G KGD +G+ G+P
Sbjct: 163 LPGPSGIT------IPGKPGAQGVPGPPGFQGEPGPQGEPGPPGDRGLKGDNGVGQPGLP 216
Query: 87 GAEGPRGFPGIQGRKGEPGEG 107
GA G G PG G G G G
Sbjct: 217 GAPGQGGAPGPPGLPGPAGLG 237
Score = 65.5 bits (158), Expect = 4e-11
Identities = 40/101 (39%), Positives = 47/101 (46%), Gaps = 9/101 (8%)
Query: 14 PGHDQETTTQGPGVLLPLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKG---- 69
PG E GP + + +AG PG PG G PG G G G KGE G
Sbjct: 375 PGPKGEAGPGGPPGVPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGR 434
Query: 70 --DPGL---IGPKGDIGETGVPGAEGPRGFPGIQGRKGEPG 105
PG+ +G KGD+G G PG GP G PG+QG G G
Sbjct: 435 PGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIG 475
Score = 63.2 bits (152), Expect = 2e-10
Identities = 35/69 (50%), Positives = 41/69 (59%), Gaps = 5/69 (7%)
Query: 42 GIPGHPGHNGAPGRDGRDGTPGE---KGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGI- 97
G PG PG GA G+ G G PG+ +G G PGL GP G IG G+PG +G G PG
Sbjct: 433 GRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPP 492
Query: 98 -QGRKGEPG 105
+GR GEPG
Sbjct: 493 GEGRAGEPG 501
Score = 61.6 bits (148), Expect = 6e-10
Identities = 40/94 (42%), Positives = 48/94 (51%), Gaps = 6/94 (6%)
Query: 15 GHDQETTTQGP-GVLLPLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGL 73
G E T+GP G++ P G M G+PG G G G G G GE GE G+PG
Sbjct: 296 GAKGEPGTRGPPGLIGPTGYG-----MPGLPGPKGDRGPAGVPGLLGDRGEPGEDGEPGE 350
Query: 74 IGPKGDIGETGVPGAEGPRGFPGIQGRKGEPGEG 107
GP+G G G+PG+ G G G G KGE G G
Sbjct: 351 QGPQGLGGPPGLPGSAGLPGRRGPPGPKGEAGPG 384
Score = 61.2 bits (147), Expect = 8e-10
Identities = 36/82 (43%), Positives = 42/82 (51%), Gaps = 8/82 (9%)
Query: 32 PKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEK------GDPGLIGPKGDI--GET 83
P G AG PG PG G PG+ G G PG +G++ G PGL GP G G+
Sbjct: 116 PPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPGKP 175
Query: 84 GVPGAEGPRGFPGIQGRKGEPG 105
G G GP GF G G +GEPG
Sbjct: 176 GAQGVPGPPGFQGEPGPQGEPG 197
Score = 60.8 bits (146), Expect = 1e-09
Identities = 34/66 (51%), Positives = 37/66 (56%), Gaps = 5/66 (7%)
Query: 42 GIPGHPGHNGAPGRDGRDGTPG--EKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQG 99
G+PG PG GAPG G G G + G G PG G KG+ G GVP GPRG PG G
Sbjct: 214 GLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVP---GPRGEPGAVG 270
Query: 100 RKGEPG 105
KG PG
Sbjct: 271 PKGPPG 276
Score = 60.8 bits (146), Expect = 1e-09
Identities = 36/80 (45%), Positives = 42/80 (52%), Gaps = 5/80 (6%)
Query: 29 LPLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGA 88
LP PKG AG+PG G G PG DG G G +G G PGL G G G G PG
Sbjct: 320 LPGPKG--DRGPAGVPGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPGRRGPPGP 377
Query: 89 E---GPRGFPGIQGRKGEPG 105
+ GP G PG+ G +G+ G
Sbjct: 378 KGEAGPGGPPGVPGIRGDQG 397
Score = 59.3 bits (142), Expect = 3e-09
Identities = 30/64 (46%), Positives = 34/64 (53%)
Query: 42 GIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRK 101
G PG G G PG G G G+ G G PGL GP G G G G GP+G PG++G
Sbjct: 427 GEPGFTGRPGGPGVAGALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEP 486
Query: 102 GEPG 105
G PG
Sbjct: 487 GLPG 490
Score = 56.6 bits (135), Expect = 2e-08
Identities = 32/72 (44%), Positives = 38/72 (52%), Gaps = 7/72 (9%)
Query: 41 AGIPGHP--GHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGF---- 94
AG PG G G PG G+ G PG+ G +G+PG+ G +G G G PG GP G
Sbjct: 114 AGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPGPSGITIPG 173
Query: 95 -PGIQGRKGEPG 105
PG QG G PG
Sbjct: 174 KPGAQGVPGPPG 185
Score = 54.7 bits (130), Expect = 7e-08
Identities = 35/90 (38%), Positives = 42/90 (46%), Gaps = 7/90 (7%)
Query: 23 QGPGVLLPLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGE-----KGDPGLIGPK 77
+G G L +P + G PG PG G G G G PG+ G G PG GP
Sbjct: 58 EGKGQYLEMPLPLLPMDLKGEPGPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPP 117
Query: 78 G--DIGETGVPGAEGPRGFPGIQGRKGEPG 105
G +G+ G PG G G PG G +GEPG
Sbjct: 118 GFSRMGKAGPPGLPGKVGPPGQPGLRGEPG 147
Score = 54.7 bits (130), Expect = 7e-08
Identities = 31/72 (43%), Positives = 36/72 (50%), Gaps = 7/72 (9%)
Query: 42 GIPGHPGHNGAPGRDGRDGTPG--EKGEKGDPGLIGPKG-----DIGETGVPGAEGPRGF 94
G PG PG G PG G G PG + G G PG GP G G G+PG GP G
Sbjct: 80 GPPGKPGPRGPPGPPGFPGKPGMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQ 139
Query: 95 PGIQGRKGEPGE 106
PG++G G G+
Sbjct: 140 PGLRGEPGIRGD 151
Score = 52.0 bits (123), Expect = 5e-07
Identities = 30/71 (42%), Positives = 36/71 (50%), Gaps = 7/71 (9%)
Query: 42 GIPGHPGHNGAPG-----RDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPG 96
G+ G PG G PG + G G PG+ G G PGL G G G+ G+ G GP G PG
Sbjct: 106 GLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGPPGLPG 165
Query: 97 IQG--RKGEPG 105
G G+PG
Sbjct: 166 PSGITIPGKPG 176
Score = 38.1 bits (87), Expect = 0.007
Identities = 30/81 (37%), Positives = 37/81 (45%), Gaps = 6/81 (7%)
Query: 32 PKGACTGWMAGIPGH-PGHNGAPGRDGRDGTPGEKGEKGD----PGLIGPKGDIGETGVP 86
P+ + G G G+ P P + G G P +G KG P + P GE G P
Sbjct: 24 PRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREG-KGQYLEMPLPLLPMDLKGEPGPP 82
Query: 87 GAEGPRGFPGIQGRKGEPGEG 107
G GPRG PG G G+PG G
Sbjct: 83 GKPGPRGPPGPPGFPGKPGMG 103
>gi|87298828 complement component 1, q subcomponent, B chain
precursor [Homo sapiens]
Length = 253
Score = 135 bits (340), Expect = 3e-32
Identities = 86/226 (38%), Positives = 119/226 (52%), Gaps = 23/226 (10%)
Query: 35 ACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAE----- 89
+CTG A IPG PG G PG DG+ GTPG KGEKG PGL G G+ GE G PG
Sbjct: 30 SCTGPPA-IPGIPGIPGTPGPDGQPGTPGIKGEKGLPGLAGDHGEFGEKGDPGIPGNPGK 88
Query: 90 -------GPRGFPGIQGRKGEPGE-GAYVYRSAFSVGLETYVTIP---NMPIRFTKIFYN 138
GP+G PG G G GE G Y + + +P + IRF + N
Sbjct: 89 VGPKGPMGPKGGPGAPGAPGPKGESGDYKATQKIAFSATRTINVPLRRDQTIRFDHVITN 148
Query: 139 QQNHYDGSTGKFHCNIPGLYYFAYHITVYMKDVKVSLFK-KDKAM-LFTYDQYQENNVDQ 196
N+Y+ +GKF C +PGLYYF YH + ++ V+L + +++A + T+ Y N
Sbjct: 149 MNNNYEPRSGKFTCKVPGLYYFTYHAS-SRGNLCVNLMRGRERAQKVVTFCDYAYNTFQV 207
Query: 197 ASGSVLLHLEVGDQVWLQVYGEGERNGLYADNDNDSTFTGFLLYHD 242
+G ++L LE G+ V+LQ ++N L +S F+GFLL+ D
Sbjct: 208 TTGGMVLKLEQGENVFLQA---TDKNSLLGMEGANSIFSGFLLFPD 250
>gi|5729785 complement component 1, q subcomponent-like 1 [Homo
sapiens]
Length = 258
Score = 127 bits (318), Expect = 1e-29
Identities = 85/233 (36%), Positives = 118/233 (50%), Gaps = 25/233 (10%)
Query: 23 QGPGVLLPLPKGACTGWMAGIPGHP----GHNGAPGRDGRDGTPGEKGEKGDPGLIGPKG 78
+GPG G +G P G G PGR G+ G PG G+ G PG +GP G
Sbjct: 38 RGPGAGARTDGGDALSEQSGAPPPSTLVQGPQGKPGRTGKPGPPGPPGDPGPPGPVGPPG 97
Query: 79 DIGETGVPGAEGPRGFPGIQGRKGEPGEGAY--VYRSAFSVGL----ETYVTIPNMPIRF 132
+ GE PG GP G PG G G Y V R AF GL E Y ++F
Sbjct: 98 EKGE---PGKPGPPGLPG-AGGSGAISTATYTTVPRVAFYAGLKNPHEGYEV-----LKF 148
Query: 133 TKIFYNQQNHYDGSTGKFHCNIPGLYYFAYHITVYMKD---VKVSLFKKDKAMLFTYDQY 189
+ N N+YD ++GKF CNIPG Y+F YH+ + D + L K + Q
Sbjct: 149 DDVVTNLGNNYDAASGKFTCNIPGTYFFTYHVLMRGGDGTSMWADLCKNGQVRASAIAQD 208
Query: 190 QENNVDQASGSVLLHLEVGDQVWLQVYGEGERNGLYADNDNDSTFTGFLLYHD 242
+ N D AS SV+LHL+ GD+V++++ G G+ +G +++ STF+GF++Y D
Sbjct: 209 ADQNYDYASNSVILHLDAGDEVFIKLDG-GKAHG--GNSNKYSTFSGFIIYSD 258
>gi|58801559 complement component 1, q subcomponent-like 3 [Homo
sapiens]
Length = 255
Score = 126 bits (316), Expect = 2e-29
Identities = 78/223 (34%), Positives = 114/223 (51%), Gaps = 35/223 (15%)
Query: 38 GWMAGIPGH-PGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPG 96
G M +P G G GR G+ G G GE G PG +GP G+ GE G G GP G PG
Sbjct: 50 GLMQSLPTFIQGPKGEAGRPGKAGPRGPPGEPGPPGPMGPPGEKGEPGRQGLPGPPGAPG 109
Query: 97 IQGRKGEPGEGAYVYRSAFSVGLETYVTIPNMP--------------IRFTKIFYNQQNH 142
+ +A ++ TY T+P + ++F + N NH
Sbjct: 110 L--------------NAAGAISAATYSTVPKIAFYAGLKRQHEGYEVLKFDDVVTNLGNH 155
Query: 143 YDGSTGKFHCNIPGLYYFAYHITVYMKD---VKVSLFKKDKAMLFTYDQYQENNVDQASG 199
YD +TGKF C+IPG+Y+F YH+ + D + L K ++ Q + N D AS
Sbjct: 156 YDPTTGKFTCSIPGIYFFTYHVLMRGGDGTSMWADLCKNNQVRASAIAQDADQNYDYASN 215
Query: 200 SVLLHLEVGDQVWLQVYGEGERNGLYADNDNDSTFTGFLLYHD 242
SV+LHLE GD+V++++ G G+ +G +N+ STF+GF++Y D
Sbjct: 216 SVVLHLEPGDEVYIKLDG-GKAHG--GNNNKYSTFSGFIIYAD 255
>gi|56606142 complement component 1, q subcomponent-like 4 [Homo
sapiens]
Length = 238
Score = 116 bits (291), Expect = 2e-26
Identities = 79/214 (36%), Positives = 110/214 (51%), Gaps = 27/214 (12%)
Query: 44 PGHPGHNGAP--------GRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFP 95
P PG +GAP G G G G+ G +G PG GP+G GE G PG GP G
Sbjct: 37 PRGPGPDGAPASVPPFPPGAKGEVGRRGKAGLRGPPGPPGPRGPPGEPGRPGPPGPPG-- 94
Query: 96 GIQGRKGEPGEGAYVYRSAFSVGL----ETYVTIPNMPIRFTKIFYNQQNHYDGSTGKFH 151
G G YV R AF GL E Y + RF + N N Y+ ++GKF
Sbjct: 95 --PGPGGVAPAAGYVPRIAFYAGLRRPHEGYEVL-----RFDDVVTNVGNAYEAASGKFT 147
Query: 152 CNIPGLYYFAYHITVYMKD---VKVSLFKKDKAMLFTYDQYQENNVDQASGSVLLHLEVG 208
C +PG+Y+FAYH+ + D + L K + Q + N D AS SV+LHL+VG
Sbjct: 148 CPMPGVYFFAYHVLMRGGDGTSMWADLMKNGQVRASAIAQDADQNYDYASNSVILHLDVG 207
Query: 209 DQVWLQVYGEGERNGLYADNDNDSTFTGFLLYHD 242
D+V++++ G G+ +G + + STF+GF++Y D
Sbjct: 208 DEVFIKLDG-GKVHG--GNTNKYSTFSGFIIYPD 238
>gi|7705753 complement component 1, q subcomponent, A chain
precursor [Homo sapiens]
Length = 245
Score = 115 bits (288), Expect = 3e-26
Identities = 70/213 (32%), Positives = 105/213 (49%), Gaps = 18/213 (8%)
Query: 42 GIPGHPGHNGAPGRDGRDGTPGE-------KGEKGDPGLIGPKGDIGETGVPGAEGP--- 91
G G PG G PG G G PG +G KGD G GP G+ G+ G PG GP
Sbjct: 34 GEAGRPGRRGRPGLKGEQGEPGAPGIRTGIQGLKGDQGEPGPSGNPGKVGYPGPSGPLGA 93
Query: 92 RGFPGIQGRKGEPGEGAYVYRSAFSVGLETYVTIPNMPIRFTKIFYNQQNHYDGSTGKFH 151
RG PGI+G KG PG R AFS + + + F + NQ+ Y +G+F
Sbjct: 94 RGIPGIKGTKGSPGNIKDQPRPAFS-AIRRNPPMGGNVVIFDTVITNQEEPYQNHSGRFV 152
Query: 152 CNIPGLYYFAYHITVYMKDVKVSLFKKDKAM----LFTYDQYQENNVDQASGSVLLHLEV 207
C +PG YYF + + + ++ +S+ + L D + SG ++L L+
Sbjct: 153 CTVPGYYYFTFQV-LSQWEICLSIVSSSRGQVRRSLGFCDTTNKGLFQVVSGGMVLQLQQ 211
Query: 208 GDQVWLQVYGEGERNGLYADNDNDSTFTGFLLY 240
GDQVW++ + ++ +Y ++ DS F+GFL++
Sbjct: 212 GDQVWVE--KDPKKGHIYQGSEADSVFSGFLIF 242
>gi|154937344 complement component 1, q subcomponent-like 2 [Homo
sapiens]
Length = 287
Score = 115 bits (288), Expect = 3e-26
Identities = 84/243 (34%), Positives = 118/243 (48%), Gaps = 37/243 (15%)
Query: 30 PLPKGACTGWMAGIPGHP------GHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGET 83
P P A M + +P G G PGR G+ G G GE G PG GP G+ G++
Sbjct: 52 PGPSTAALEVMQDLSANPPPPFIQGPKGDPGRPGKPGPRGPPGEPGPPGPRGPPGEKGDS 111
Query: 84 GVPGAEGPRGFPGIQGRKGEPGEGAYV------------------YRSAFSVGLETYVTI 125
G PG G + G G G GA V + AF VGL++
Sbjct: 112 GRPGLPGLQLTAGTASGVGVVGGGAGVGGDSEGEVTSALSATFSGPKIAFYVGLKS---- 167
Query: 126 PN---MPIRFTKIFYNQQNHYDGSTGKFHCNIPGLYYFAYHITVYMKD---VKVSLFKKD 179
P+ ++F + N NHYD +TGKF C + G+Y+F YHI + D + L K
Sbjct: 168 PHEGYEVLKFDDVVTNLGNHYDPTTGKFSCQVRGIYFFTYHILMRGGDGTSMWADLCKNG 227
Query: 180 KAMLFTYDQYQENNVDQASGSVLLHLEVGDQVWLQVYGEGERNGLYADNDNDSTFTGFLL 239
+ Q + N D AS SV+LHL+ GD+V++++ G G+ +G +N+ STF+GFLL
Sbjct: 228 QVRASAIAQDADQNYDYASNSVVLHLDSGDEVYVKLDG-GKAHG--GNNNKYSTFSGFLL 284
Query: 240 YHD 242
Y D
Sbjct: 285 YPD 287
>gi|13569919 C1q and tumor necrosis factor related protein 3 isoform
a [Homo sapiens]
Length = 246
Score = 108 bits (271), Expect = 3e-24
Identities = 70/201 (34%), Positives = 104/201 (51%), Gaps = 19/201 (9%)
Query: 42 GIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRK 101
G PG PG++G G +G G G KGEKGD G +GP+ GE G G +G +G+PGI
Sbjct: 60 GPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPR---GERGQHGPKGEKGYPGI---- 112
Query: 102 GEPGEGAYVYRSAFSVGLETYVTIPNMPIRFTKIFYNQQNHYDGSTGKFHCNIPGLYYFA 161
P E + AF L T+ + N I F+ + N N +D TG+F + G+Y+F
Sbjct: 113 --PPE----LQIAFMASLATHFSNQNSGIIFSSVETNIGNFFDVMTGRFGAPVSGVYFFT 166
Query: 162 YHITVY--MKDVKVSLFKKDKAMLFTYDQYQENNVDQASGSVLLHLEVGDQVWLQVYGEG 219
+ + + +++V V L + Y + D +S +L L GD+VWL++ G G
Sbjct: 167 FSMMKHEDVEEVYVYLMHNGNTVFSMYSYEMKGKSDTSSNHAVLKLAKGDEVWLRM-GNG 225
Query: 220 ERNGLYADNDNDSTFTGFLLY 240
L+ D+ STF GFLL+
Sbjct: 226 ---ALHGDHQRFSTFAGFLLF 243
>gi|62739183 C1q and tumor necrosis factor related protein 3 isoform
b [Homo sapiens]
Length = 319
Score = 108 bits (271), Expect = 3e-24
Identities = 70/201 (34%), Positives = 104/201 (51%), Gaps = 19/201 (9%)
Query: 42 GIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRK 101
G PG PG++G G +G G G KGEKGD G +GP+ GE G G +G +G+PGI
Sbjct: 133 GPPGIPGNHGNNGNNGATGHEGAKGEKGDKGDLGPR---GERGQHGPKGEKGYPGI---- 185
Query: 102 GEPGEGAYVYRSAFSVGLETYVTIPNMPIRFTKIFYNQQNHYDGSTGKFHCNIPGLYYFA 161
P E + AF L T+ + N I F+ + N N +D TG+F + G+Y+F
Sbjct: 186 --PPE----LQIAFMASLATHFSNQNSGIIFSSVETNIGNFFDVMTGRFGAPVSGVYFFT 239
Query: 162 YHITVY--MKDVKVSLFKKDKAMLFTYDQYQENNVDQASGSVLLHLEVGDQVWLQVYGEG 219
+ + + +++V V L + Y + D +S +L L GD+VWL++ G G
Sbjct: 240 FSMMKHEDVEEVYVYLMHNGNTVFSMYSYEMKGKSDTSSNHAVLKLAKGDEVWLRM-GNG 298
Query: 220 ERNGLYADNDNDSTFTGFLLY 240
L+ D+ STF GFLL+
Sbjct: 299 ---ALHGDHQRFSTFAGFLLF 316
>gi|38372917 C1q and tumor necrosis factor related protein 1 isoform
1 [Homo sapiens]
Length = 281
Score = 106 bits (265), Expect = 2e-23
Identities = 63/183 (34%), Positives = 104/183 (56%), Gaps = 5/183 (2%)
Query: 65 KGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRKGEPGEGAYVYRSAFSVGLETYVT 124
KGEKGD G G +G G+TG GA G G G +G G PGE + +AFSVG + +
Sbjct: 98 KGEKGDRGDRGLQGKYGKTGSAGARGHTGPKGQKGSMGAPGERCKSHYAAFSVGRKKPMH 157
Query: 125 IPN--MPIRFTKIFYNQQNHYDGSTGKFHCNIPGLYYFAYHI-TVYMKDVKVSLFKKDKA 181
+ + F F N +H++ TGKF+C +PGLY+F+ ++ T K+ + + K ++
Sbjct: 158 SNHYYQTVIFDTEFVNLYDHFNMFTGKFYCYVPGLYFFSLNVHTWNQKETYLHIMKNEEE 217
Query: 182 MLFTYDQYQENNVDQASGSVLLHLEVGDQVWLQVYGEGERNGLYADN-DNDSTFTGFLLY 240
++ + Q + ++ Q S S++L L DQVW+++Y N ++++ D TF+G+L+
Sbjct: 218 VVILFAQVGDRSIMQ-SQSLMLELREQDQVWVRLYKGERENAIFSEELDTYITFSGYLVK 276
Query: 241 HDT 243
H T
Sbjct: 277 HAT 279
>gi|38372913 C1q and tumor necrosis factor related protein 1 [Homo
sapiens]
Length = 199
Score = 106 bits (265), Expect = 2e-23
Identities = 63/183 (34%), Positives = 104/183 (56%), Gaps = 5/183 (2%)
Query: 65 KGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRKGEPGEGAYVYRSAFSVGLETYVT 124
KGEKGD G G +G G+TG GA G G G +G G PGE + +AFSVG + +
Sbjct: 16 KGEKGDRGDRGLQGKYGKTGSAGARGHTGPKGQKGSMGAPGERCKSHYAAFSVGRKKPMH 75
Query: 125 IPN--MPIRFTKIFYNQQNHYDGSTGKFHCNIPGLYYFAYHI-TVYMKDVKVSLFKKDKA 181
+ + F F N +H++ TGKF+C +PGLY+F+ ++ T K+ + + K ++
Sbjct: 76 SNHYYQTVIFDTEFVNLYDHFNMFTGKFYCYVPGLYFFSLNVHTWNQKETYLHIMKNEEE 135
Query: 182 MLFTYDQYQENNVDQASGSVLLHLEVGDQVWLQVYGEGERNGLYADN-DNDSTFTGFLLY 240
++ + Q + ++ Q S S++L L DQVW+++Y N ++++ D TF+G+L+
Sbjct: 136 VVILFAQVGDRSIMQ-SQSLMLELREQDQVWVRLYKGERENAIFSEELDTYITFSGYLVK 194
Query: 241 HDT 243
H T
Sbjct: 195 HAT 197
>gi|13569944 C1q and tumor necrosis factor related protein 1 isoform
1 [Homo sapiens]
Length = 281
Score = 106 bits (265), Expect = 2e-23
Identities = 63/183 (34%), Positives = 104/183 (56%), Gaps = 5/183 (2%)
Query: 65 KGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRKGEPGEGAYVYRSAFSVGLETYVT 124
KGEKGD G G +G G+TG GA G G G +G G PGE + +AFSVG + +
Sbjct: 98 KGEKGDRGDRGLQGKYGKTGSAGARGHTGPKGQKGSMGAPGERCKSHYAAFSVGRKKPMH 157
Query: 125 IPN--MPIRFTKIFYNQQNHYDGSTGKFHCNIPGLYYFAYHI-TVYMKDVKVSLFKKDKA 181
+ + F F N +H++ TGKF+C +PGLY+F+ ++ T K+ + + K ++
Sbjct: 158 SNHYYQTVIFDTEFVNLYDHFNMFTGKFYCYVPGLYFFSLNVHTWNQKETYLHIMKNEEE 217
Query: 182 MLFTYDQYQENNVDQASGSVLLHLEVGDQVWLQVYGEGERNGLYADN-DNDSTFTGFLLY 240
++ + Q + ++ Q S S++L L DQVW+++Y N ++++ D TF+G+L+
Sbjct: 218 VVILFAQVGDRSIMQ-SQSLMLELREQDQVWVRLYKGERENAIFSEELDTYITFSGYLVK 276
Query: 241 HDT 243
H T
Sbjct: 277 HAT 279
>gi|32967300 C1q and tumor necrosis factor related protein 6 [Homo
sapiens]
Length = 278
Score = 98.6 bits (244), Expect = 4e-21
Identities = 60/179 (33%), Positives = 95/179 (53%), Gaps = 5/179 (2%)
Query: 65 KGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRKGEPGEGAYVYRSAFSVGLETYVT 124
KG+KGDPG +G G +G G G GP+G G +G G PG AFSVG +T +
Sbjct: 96 KGDKGDPGPMGLPGYMGREGPQGEPGPQGSKGDKGEMGSPGAPCQKRFFAFSVGRKTALH 155
Query: 125 IPN--MPIRFTKIFYNQQNHYDGSTGKFHCNIPGLYYFAYHITVY-MKDVKVSLFKKDKA 181
+ F ++F N +D +TG+F + G+Y+F+ ++ + K+ V + K
Sbjct: 156 SGEDFQTLLFERVFVNLDGCFDMATGQFAAPLRGIYFFSLNVHSWNYKETYVHIMHNQKE 215
Query: 182 MLFTYDQYQENNVDQASGSVLLHLEVGDQVWLQVYGEGERNGLYA-DNDNDSTFTGFLL 239
+ Y Q E ++ Q S SV+L L GD+VW++++ N +Y+ D D TF+G L+
Sbjct: 216 AVILYAQPSERSIMQ-SQSVMLDLAYGDRVWVRLFKRQRENAIYSNDFDTYITFSGHLI 273
>gi|32967294 C1q and tumor necrosis factor related protein 6 [Homo
sapiens]
Length = 278
Score = 98.6 bits (244), Expect = 4e-21
Identities = 60/179 (33%), Positives = 95/179 (53%), Gaps = 5/179 (2%)
Query: 65 KGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRKGEPGEGAYVYRSAFSVGLETYVT 124
KG+KGDPG +G G +G G G GP+G G +G G PG AFSVG +T +
Sbjct: 96 KGDKGDPGPMGLPGYMGREGPQGEPGPQGSKGDKGEMGSPGAPCQKRFFAFSVGRKTALH 155
Query: 125 IPN--MPIRFTKIFYNQQNHYDGSTGKFHCNIPGLYYFAYHITVY-MKDVKVSLFKKDKA 181
+ F ++F N +D +TG+F + G+Y+F+ ++ + K+ V + K
Sbjct: 156 SGEDFQTLLFERVFVNLDGCFDMATGQFAAPLRGIYFFSLNVHSWNYKETYVHIMHNQKE 215
Query: 182 MLFTYDQYQENNVDQASGSVLLHLEVGDQVWLQVYGEGERNGLYA-DNDNDSTFTGFLL 239
+ Y Q E ++ Q S SV+L L GD+VW++++ N +Y+ D D TF+G L+
Sbjct: 216 AVILYAQPSERSIMQ-SQSVMLDLAYGDRVWVRLFKRQRENAIYSNDFDTYITFSGHLI 273
>gi|116686136 C1q and tumor necrosis factor related protein 8 [Homo
sapiens]
Length = 252
Score = 85.5 bits (210), Expect = 4e-17
Identities = 56/179 (31%), Positives = 91/179 (50%), Gaps = 5/179 (2%)
Query: 65 KGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRKGEPGEGAYVYRSAFSVGLETYVT 124
KGEKG+ G+ G G G+ G PGA G +G G +G+ G PG +AFSVG +
Sbjct: 69 KGEKGEAGVRGRAGRSGKEGPPGARGLQGRRGQKGQVGPPGAACRRAYAAFSVGRREGLH 128
Query: 125 IPN--MPIRFTKIFYNQQNHYDGSTGKFHCNIPGLYYFAYHI-TVYMKDVKVSLFKKDKA 181
+ + F N +D + G+F C +PG+Y+ + ++ T K+ + + +
Sbjct: 129 SSDHFQAVPFDTELVNLDGAFDLAAGRFLCTVPGVYFLSLNVHTWNYKETYLHIMLNRRP 188
Query: 182 MLFTYDQYQENNVDQASGSVLLHLEVGDQVWLQVYGEGERNGLYADN-DNDSTFTGFLL 239
Y Q E +V QA S++L L GD VW++++ N +Y ++ D TF+G L+
Sbjct: 189 AAVLYAQPSERSVMQAQ-SLMLLLAAGDAVWVRMFQRDRDNAIYGEHGDLYITFSGHLV 246
>gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens]
Length = 1028
Score = 78.2 bits (191), Expect = 6e-15
Identities = 37/66 (56%), Positives = 42/66 (63%)
Query: 41 AGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGR 100
AG PG G +G G+ G G PGEKGE GD G GP G GE G PG GPRG PG +G
Sbjct: 382 AGRPGSSGPSGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGP 441
Query: 101 KGEPGE 106
+G+PGE
Sbjct: 442 RGDPGE 447
Score = 67.4 bits (163), Expect = 1e-11
Identities = 36/74 (48%), Positives = 42/74 (56%), Gaps = 7/74 (9%)
Query: 42 GIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGD------IGETGVPGAEGPRGFP 95
G G PG G PG G GTPG +G +GDPG GP+GD +G G PG GP G
Sbjct: 416 GPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPK 475
Query: 96 GIQGRKGEPG-EGA 108
G +G +G PG EGA
Sbjct: 476 GYRGDEGPPGSEGA 489
Score = 66.6 bits (161), Expect = 2e-11
Identities = 35/74 (47%), Positives = 42/74 (56%), Gaps = 2/74 (2%)
Query: 32 PKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGP 91
P+G T G G PG G G GR+G G G+ G+ G IGPKG G+ G PG+EG
Sbjct: 432 PRG--TPGTRGPRGDPGEAGPQGDQGREGPVGVPGDPGEAGPIGPKGYRGDEGPPGSEGA 489
Query: 92 RGFPGIQGRKGEPG 105
RG PG G G+PG
Sbjct: 490 RGAPGPAGPPGDPG 503
Score = 66.2 bits (160), Expect = 2e-11
Identities = 43/100 (43%), Positives = 48/100 (48%), Gaps = 6/100 (6%)
Query: 13 LPGHDQETTTQG-PGVLLPLPKGACTGWMA-----GIPGHPGHNGAPGRDGRDGTPGEKG 66
LPG E G PG L P+ G G G G+ G G+ G DG G KG
Sbjct: 276 LPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPKGYKGEKGKRGIDGVDGVKG 335
Query: 67 EKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRKGEPGE 106
E G PGL G KG G G+ G GP+G PG G KGE GE
Sbjct: 336 EMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGE 375
Score = 66.2 bits (160), Expect = 2e-11
Identities = 35/68 (51%), Positives = 39/68 (57%), Gaps = 3/68 (4%)
Query: 42 GIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGD---IGETGVPGAEGPRGFPGIQ 98
G PG PG G+PG DG G PG KG+ G GL G KG+ GE G PG+ GP G G
Sbjct: 338 GYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQP 397
Query: 99 GRKGEPGE 106
G G PGE
Sbjct: 398 GEPGPPGE 405
Score = 65.9 bits (159), Expect = 3e-11
Identities = 37/78 (47%), Positives = 44/78 (56%), Gaps = 7/78 (8%)
Query: 32 PKGACTGWMAGIPGHPGHNGAPGRDGRDGTP---GEKGEKGDPG----LIGPKGDIGETG 84
P G T G PG+PG+ GAPG +G G P G++GE GDPG I P+G G G
Sbjct: 513 PAGNGTEGFPGFPGYPGNRGAPGINGTKGYPGLKGDEGEAGDPGDDNNDIAPRGVKGAKG 572
Query: 85 VPGAEGPRGFPGIQGRKG 102
G EGP+G PG QG G
Sbjct: 573 YRGPEGPQGPPGHQGPPG 590
Score = 63.2 bits (152), Expect = 2e-10
Identities = 32/65 (49%), Positives = 37/65 (56%)
Query: 42 GIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRK 101
G PG G G G G+ G PGEKGE GDPG G G +G G+ G +G RG G +G K
Sbjct: 257 GPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGPK 316
Query: 102 GEPGE 106
G GE
Sbjct: 317 GYKGE 321
Score = 63.2 bits (152), Expect = 2e-10
Identities = 39/95 (41%), Positives = 48/95 (50%), Gaps = 12/95 (12%)
Query: 14 PGHDQETTTQGPGVLLPLPKGACTGWMAGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGL 73
PG + E G LP KG AG PG PG G G G G G +GEKG G
Sbjct: 265 PGFEGERGKPG----LPGEKGE-----AGDPGRPGDLGPVGYQGMKGEKGSRGEKGSRGP 315
Query: 74 IGPKGDIGETGVPGAEGPR---GFPGIQGRKGEPG 105
G KG+ G+ G+ G +G + G+PG+ G KG PG
Sbjct: 316 KGYKGEKGKRGIDGVDGVKGEMGYPGLPGCKGSPG 350
Score = 60.1 bits (144), Expect = 2e-09
Identities = 31/67 (46%), Positives = 36/67 (53%), Gaps = 3/67 (4%)
Query: 42 GIPGHPGHNGAPGRDGRDGT---PGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQ 98
G G G G PG DG G PGE+G +G PG GP+GD GE G G +G G G+
Sbjct: 404 GEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVGVP 463
Query: 99 GRKGEPG 105
G GE G
Sbjct: 464 GDPGEAG 470
Score = 59.7 bits (143), Expect = 2e-09
Identities = 32/75 (42%), Positives = 38/75 (50%), Gaps = 11/75 (14%)
Query: 42 GIPGHPGHNGA---PGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPR------ 92
G+PG PG G G G +G PG +G +G PG GP GD G G G +GP
Sbjct: 461 GVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEG 520
Query: 93 --GFPGIQGRKGEPG 105
GFPG G +G PG
Sbjct: 521 FPGFPGYPGNRGAPG 535
Score = 59.3 bits (142), Expect = 3e-09
Identities = 28/55 (50%), Positives = 35/55 (63%)
Query: 52 APGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRKGEPGE 106
A G G G PG +GE+G PGL G KG+ G+ G PG GP G+ G++G KG GE
Sbjct: 255 ARGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGYQGMKGEKGSRGE 309
Score = 58.5 bits (140), Expect = 5e-09
Identities = 29/64 (45%), Positives = 34/64 (53%), Gaps = 6/64 (9%)
Query: 42 GIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRK 101
G PG PG G G +G G G GE+G PG GP+ G PG GPRG PG G +
Sbjct: 398 GEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPR------GTPGTRGPRGDPGEAGPQ 451
Query: 102 GEPG 105
G+ G
Sbjct: 452 GDQG 455
Score = 58.5 bits (140), Expect = 5e-09
Identities = 30/85 (35%), Positives = 41/85 (48%), Gaps = 20/85 (23%)
Query: 42 GIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETG----------------- 84
G G+ G G PG +G G PG G GDPGL+G +G+ G G
Sbjct: 473 GPKGYRGDEGPPGSEGARGAPGPAGPPGDPGLMGERGEDGPAGNGTEGFPGFPGYPGNRG 532
Query: 85 VPGAEGPRGFPGI---QGRKGEPGE 106
PG G +G+PG+ +G G+PG+
Sbjct: 533 APGINGTKGYPGLKGDEGEAGDPGD 557
Score = 57.0 bits (136), Expect = 1e-08
Identities = 31/71 (43%), Positives = 36/71 (50%), Gaps = 6/71 (8%)
Query: 42 GIPGHPGHNGAPGRDGRDGTP------GEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFP 95
G+ G G G PG G G+P G G KGDPG G KG+ GE G G G G
Sbjct: 329 GVDGVKGEMGYPGLPGCKGSPGFDGIQGPPGPKGDPGAFGLKGEKGEPGADGEAGRPGSS 388
Query: 96 GIQGRKGEPGE 106
G G +G+PGE
Sbjct: 389 GPSGDEGQPGE 399
Score = 52.4 bits (124), Expect = 4e-07
Identities = 28/66 (42%), Positives = 36/66 (54%), Gaps = 7/66 (10%)
Query: 41 AGIPGHPGHNGAPGRDGRDGTPGEKGEKGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGR 100
AG PG PG G G DG P G +G PG G G+ G PG G +G+PG++G
Sbjct: 496 AGPPGDPGLMGERGEDG----PAGNGTEGFPGFPGYPGN---RGAPGINGTKGYPGLKGD 548
Query: 101 KGEPGE 106
+GE G+
Sbjct: 549 EGEAGD 554
Score = 37.4 bits (85), Expect = 0.012
Identities = 19/42 (45%), Positives = 22/42 (52%)
Query: 68 KGDPGLIGPKGDIGETGVPGAEGPRGFPGIQGRKGEPGEGAY 109
+G PGL G G GE G PG G +G G GR G+ G Y
Sbjct: 256 RGPPGLRGDPGFEGERGKPGLPGEKGEAGDPGRPGDLGPVGY 297
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.142 0.445
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,788,284
Number of Sequences: 37866
Number of extensions: 696510
Number of successful extensions: 26272
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 202
Number of HSP's successfully gapped in prelim test: 122
Number of HSP's that attempted gapping in prelim test: 2127
Number of HSP's gapped (non-prelim): 6721
length of query: 244
length of database: 18,247,518
effective HSP length: 99
effective length of query: 145
effective length of database: 14,498,784
effective search space: 2102323680
effective search space used: 2102323680
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.