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Search of human proteins with 4507207
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507207 sorcin isoform a [Homo sapiens]
(198 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507207 sorcin isoform a [Homo sapiens] 417 e-117
gi|38679884 sorcin isoform b [Homo sapiens] 377 e-105
gi|6912388 grancalcin, EF-hand calcium binding protein [Homo sap... 246 9e-66
gi|6912582 penta-EF-hand domain containing 1 [Homo sapiens] 121 3e-28
gi|7019485 programmed cell death 6 [Homo sapiens] 119 1e-27
gi|4502565 calpain, small subunit 1 [Homo sapiens] 106 1e-23
gi|51599151 calpain, small subunit 1 [Homo sapiens] 106 1e-23
gi|47078247 calpain 3 isoform f [Homo sapiens] 102 2e-22
gi|4557405 calpain 3 isoform a [Homo sapiens] 102 2e-22
gi|27765072 calpain 3 isoform b [Homo sapiens] 102 2e-22
gi|27765076 calpain 3 isoform d [Homo sapiens] 102 2e-22
gi|27765074 calpain 3 isoform c [Homo sapiens] 102 2e-22
gi|14161692 calpain small subunit 2 [Homo sapiens] 99 2e-21
gi|221554549 calpain 8 [Homo sapiens] 99 3e-21
gi|12408656 calpain 1, large subunit [Homo sapiens] 95 4e-20
gi|7705383 calpain 9 isoform 2 [Homo sapiens] 94 6e-20
gi|5729758 calpain 9 isoform 1 [Homo sapiens] 94 6e-20
gi|157389005 calpain 2 isoform 1 [Homo sapiens] 94 8e-20
gi|225703100 calpain 2 isoform 2 [Homo sapiens] 94 8e-20
gi|27765080 calpain 3 isoform e [Homo sapiens] 92 3e-19
gi|27765078 calpain 3 isoform e [Homo sapiens] 92 3e-19
gi|215490104 calpain 11 [Homo sapiens] 91 8e-19
gi|38707981 calpain 12 [Homo sapiens] 63 1e-10
gi|41152101 calpain 13 [Homo sapiens] 54 1e-07
gi|223468608 calpain 14 [Homo sapiens] 52 4e-07
gi|4885111 calmodulin-like 3 [Homo sapiens] 45 4e-05
gi|56699407 solute carrier family 25, member 25 isoform c [Homo ... 45 5e-05
gi|239755176 PREDICTED: similar to solute carrier family 25, mem... 44 1e-04
gi|239755174 PREDICTED: similar to solute carrier family 25, mem... 44 1e-04
gi|56699401 solute carrier family 25, member 25 isoform a [Homo ... 44 1e-04
>gi|4507207 sorcin isoform a [Homo sapiens]
Length = 198
Score = 417 bits (1072), Expect = e-117
Identities = 198/198 (100%), Positives = 198/198 (100%)
Query: 1 MAYPGHPGAGGGYYPGGYGGAPGGPAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLTQ 60
MAYPGHPGAGGGYYPGGYGGAPGGPAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLTQ
Sbjct: 1 MAYPGHPGAGGGYYPGGYGGAPGGPAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLTQ 60
Query: 61 SGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTV 120
SGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTV
Sbjct: 61 SGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTV 120
Query: 121 DPQELQKALTTMGFRLSPQAVNSIAKRYSTNGKITFDDYIACCVKLRALTDSFRRRDTAQ 180
DPQELQKALTTMGFRLSPQAVNSIAKRYSTNGKITFDDYIACCVKLRALTDSFRRRDTAQ
Sbjct: 121 DPQELQKALTTMGFRLSPQAVNSIAKRYSTNGKITFDDYIACCVKLRALTDSFRRRDTAQ 180
Query: 181 QGVVNFPYDDFIQCVMSV 198
QGVVNFPYDDFIQCVMSV
Sbjct: 181 QGVVNFPYDDFIQCVMSV 198
>gi|38679884 sorcin isoform b [Homo sapiens]
Length = 183
Score = 377 bits (967), Expect = e-105
Identities = 181/181 (100%), Positives = 181/181 (100%)
Query: 18 YGGAPGGPAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLTQSGIAGGYKPFNLETCRL 77
YGGAPGGPAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLTQSGIAGGYKPFNLETCRL
Sbjct: 3 YGGAPGGPAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLTQSGIAGGYKPFNLETCRL 62
Query: 78 MVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLS 137
MVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLS
Sbjct: 63 MVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLS 122
Query: 138 PQAVNSIAKRYSTNGKITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVMS 197
PQAVNSIAKRYSTNGKITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVMS
Sbjct: 123 PQAVNSIAKRYSTNGKITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVMS 182
Query: 198 V 198
V
Sbjct: 183 V 183
>gi|6912388 grancalcin, EF-hand calcium binding protein [Homo
sapiens]
Length = 217
Score = 246 bits (628), Expect = 9e-66
Identities = 122/217 (56%), Positives = 153/217 (70%), Gaps = 19/217 (8%)
Query: 1 MAYPGHPGAGGGY---YPGGYGGAP-------------GGPAFP---GQTQDPLYGYFAA 41
MAYPG+ G G + PG G P GPA+ D +Y YF+A
Sbjct: 1 MAYPGYGGGFGNFSIQVPGMQMGQPVPETGPAILLDGYSGPAYSDTYSSAGDSVYTYFSA 60
Query: 42 VAGQDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAV 101
VAGQDG++DA+ELQRCLTQSGI G Y PF+LETCR+M++MLDRD +G MGFN FKELWA
Sbjct: 61 VAGQDGEVDAEELQRCLTQSGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAA 120
Query: 102 LNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNGKITFDDYIA 161
LN W+++F++ D D SGTV+ EL++A+ MG+RLSPQ + +I KRYS NG+I FDDY+A
Sbjct: 121 LNAWKENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYSKNGRIFFDDYVA 180
Query: 162 CCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVMSV 198
CCVKLRALTD FR+RD QQG NF YDDF+Q M++
Sbjct: 181 CCVKLRALTDFFRKRDHLQQGSANFIYDDFLQGTMAI 217
>gi|6912582 penta-EF-hand domain containing 1 [Homo sapiens]
Length = 284
Score = 121 bits (304), Expect = 3e-28
Identities = 80/228 (35%), Positives = 113/228 (49%), Gaps = 34/228 (14%)
Query: 4 PGHPGAGGGYY------------PGG-YGGA-PGGP------AFPGQTQDPLYGYFAAVA 43
P P AGGG Y PGG YGGA PGGP + G Q LYG A
Sbjct: 54 PYGPPAGGGPYGHPNPGMFPSGTPGGPYGGAAPGGPYGQPPPSSYGAQQPGLYGQGGAPP 113
Query: 44 GQDGQ-------IDADEL----QRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGF 92
D + +D+D + L Q+ + + FN ETC +M++M D+ SG +
Sbjct: 114 NVDPEAYSWFQSVDSDHSGYISMKELKQALVNCNWSSFNDETCLMMINMFDKTKSGRIDV 173
Query: 93 NEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRY---S 149
F LW + W+ F +D DRSG++ ELQ+AL+ MG+ LSPQ + RY S
Sbjct: 174 YGFSALWKFIQQWKNLFQQYDRDRSGSISYTELQQALSQMGYNLSPQFTQLLVSRYCPRS 233
Query: 150 TNGKITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVMS 197
N + D +I C +L+ LT++FR +DTA QG + ++DF+ S
Sbjct: 234 ANPAMQLDRFIQVCTQLQVLTEAFREKDTAVQGNIRLSFEDFVTMTAS 281
>gi|7019485 programmed cell death 6 [Homo sapiens]
Length = 191
Score = 119 bits (299), Expect = 1e-27
Identities = 73/200 (36%), Positives = 108/200 (54%), Gaps = 15/200 (7%)
Query: 2 AYPGHPGAGGGYYPGGYGGAPGGPAFPGQTQDPLYGYFAAV-AGQDGQIDADELQRCLTQ 60
AY PG G G PG GA A P Q+ L+ F V + G I ELQ+ L+
Sbjct: 3 AYSYRPGPGAG--PGPAAGA----ALPDQSF--LWNVFQRVDKDRSGVISDTELQQALSN 54
Query: 61 SGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTV 120
G + PFN T R ++SM DR+ + F+EF +W + W+ F ++D D SG +
Sbjct: 55 ----GTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMI 110
Query: 121 DPQELQKALTTMGFRLSPQAVNSIAKRYSTNGK--ITFDDYIACCVKLRALTDSFRRRDT 178
D EL++AL+ G+RLS Q + + +++ G+ I FDD+I C+ L+ LTD FRR DT
Sbjct: 111 DKNELKQALSGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDT 170
Query: 179 AQQGVVNFPYDDFIQCVMSV 198
Q G + Y+ ++ V S+
Sbjct: 171 DQDGWIQVSYEQYLSMVFSI 190
>gi|4502565 calpain, small subunit 1 [Homo sapiens]
Length = 268
Score = 106 bits (264), Expect = 1e-23
Identities = 72/230 (31%), Positives = 104/230 (45%), Gaps = 38/230 (16%)
Query: 5 GHPGAGGGYYPGGYGGAPGGPA-----------------FPGQTQDPLYGY--------- 38
G G GGG GG GG GG A + + P Y
Sbjct: 37 GGGGGGGGGGGGGGGGGGGGTAMRILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESE 96
Query: 39 --------FAAVAGQDGQIDADELQRCLTQSGIAGG---YKPFNLETCRLMVSMLDRDMS 87
FA +AG D ++ A EL L + F ++TCR MV+++D D +
Sbjct: 97 EVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTT 156
Query: 88 GTMGFNEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKR 147
G +GF EFK LW + W+ + FDTDRSGT+ EL A GF L+ N I +R
Sbjct: 157 GKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRR 216
Query: 148 YS-TNGKITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVM 196
YS +G + FD++I+C V+L A+ +F+ D G + +++Q M
Sbjct: 217 YSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTM 266
>gi|51599151 calpain, small subunit 1 [Homo sapiens]
Length = 268
Score = 106 bits (264), Expect = 1e-23
Identities = 72/230 (31%), Positives = 104/230 (45%), Gaps = 38/230 (16%)
Query: 5 GHPGAGGGYYPGGYGGAPGGPA-----------------FPGQTQDPLYGY--------- 38
G G GGG GG GG GG A + + P Y
Sbjct: 37 GGGGGGGGGGGGGGGGGGGGTAMRILGGVISAISEAAAQYNPEPPPPRTHYSNIEANESE 96
Query: 39 --------FAAVAGQDGQIDADELQRCLTQSGIAGG---YKPFNLETCRLMVSMLDRDMS 87
FA +AG D ++ A EL L + F ++TCR MV+++D D +
Sbjct: 97 EVRQFRRLFAQLAGDDMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTT 156
Query: 88 GTMGFNEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKR 147
G +GF EFK LW + W+ + FDTDRSGT+ EL A GF L+ N I +R
Sbjct: 157 GKLGFEEFKYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRR 216
Query: 148 YS-TNGKITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVM 196
YS +G + FD++I+C V+L A+ +F+ D G + +++Q M
Sbjct: 217 YSDESGNMDFDNFISCLVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTM 266
>gi|47078247 calpain 3 isoform f [Homo sapiens]
Length = 728
Score = 102 bits (255), Expect = 2e-22
Identities = 57/181 (31%), Positives = 93/181 (51%), Gaps = 8/181 (4%)
Query: 22 PGGPAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLTQSGIAGGYKP-----FNLETCR 76
PG + Q F +AG D +I ADEL++ L + +K F LE+CR
Sbjct: 548 PGSSDQESEEQQQFRNIFKQIAGDDMEICADELKKVLNT--VVNKHKDLKTHGFTLESCR 605
Query: 77 LMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRL 136
M++++D D SG + EF LW + W++ F +DTD+SGT++ E++ A+ GF L
Sbjct: 606 SMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHL 665
Query: 137 SPQAVNSIAKRYS-TNGKITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCV 195
+ Q + I RY+ + I FD +I C V+L + +F D G++ +++Q
Sbjct: 666 NNQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLT 725
Query: 196 M 196
M
Sbjct: 726 M 726
>gi|4557405 calpain 3 isoform a [Homo sapiens]
Length = 821
Score = 102 bits (255), Expect = 2e-22
Identities = 57/181 (31%), Positives = 93/181 (51%), Gaps = 8/181 (4%)
Query: 22 PGGPAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLTQSGIAGGYKP-----FNLETCR 76
PG + Q F +AG D +I ADEL++ L + +K F LE+CR
Sbjct: 641 PGSSDQESEEQQQFRNIFKQIAGDDMEICADELKKVLNT--VVNKHKDLKTHGFTLESCR 698
Query: 77 LMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRL 136
M++++D D SG + EF LW + W++ F +DTD+SGT++ E++ A+ GF L
Sbjct: 699 SMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHL 758
Query: 137 SPQAVNSIAKRYS-TNGKITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCV 195
+ Q + I RY+ + I FD +I C V+L + +F D G++ +++Q
Sbjct: 759 NNQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLT 818
Query: 196 M 196
M
Sbjct: 819 M 819
>gi|27765072 calpain 3 isoform b [Homo sapiens]
Length = 815
Score = 102 bits (255), Expect = 2e-22
Identities = 57/181 (31%), Positives = 93/181 (51%), Gaps = 8/181 (4%)
Query: 22 PGGPAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLTQSGIAGGYKP-----FNLETCR 76
PG + Q F +AG D +I ADEL++ L + +K F LE+CR
Sbjct: 635 PGSSDQESEEQQQFRNIFKQIAGDDMEICADELKKVLNT--VVNKHKDLKTHGFTLESCR 692
Query: 77 LMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRL 136
M++++D D SG + EF LW + W++ F +DTD+SGT++ E++ A+ GF L
Sbjct: 693 SMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHL 752
Query: 137 SPQAVNSIAKRYS-TNGKITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCV 195
+ Q + I RY+ + I FD +I C V+L + +F D G++ +++Q
Sbjct: 753 NNQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLT 812
Query: 196 M 196
M
Sbjct: 813 M 813
>gi|27765076 calpain 3 isoform d [Homo sapiens]
Length = 309
Score = 102 bits (255), Expect = 2e-22
Identities = 57/181 (31%), Positives = 93/181 (51%), Gaps = 8/181 (4%)
Query: 22 PGGPAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLTQSGIAGGYKP-----FNLETCR 76
PG + Q F +AG D +I ADEL++ L + +K F LE+CR
Sbjct: 129 PGSSDQESEEQQQFRNIFKQIAGDDMEICADELKKVLNT--VVNKHKDLKTHGFTLESCR 186
Query: 77 LMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRL 136
M++++D D SG + EF LW + W++ F +DTD+SGT++ E++ A+ GF L
Sbjct: 187 SMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHL 246
Query: 137 SPQAVNSIAKRYS-TNGKITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCV 195
+ Q + I RY+ + I FD +I C V+L + +F D G++ +++Q
Sbjct: 247 NNQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLT 306
Query: 196 M 196
M
Sbjct: 307 M 307
>gi|27765074 calpain 3 isoform c [Homo sapiens]
Length = 729
Score = 102 bits (255), Expect = 2e-22
Identities = 57/181 (31%), Positives = 93/181 (51%), Gaps = 8/181 (4%)
Query: 22 PGGPAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLTQSGIAGGYKP-----FNLETCR 76
PG + Q F +AG D +I ADEL++ L + +K F LE+CR
Sbjct: 549 PGSSDQESEEQQQFRNIFKQIAGDDMEICADELKKVLNT--VVNKHKDLKTHGFTLESCR 606
Query: 77 LMVSMLDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRL 136
M++++D D SG + EF LW + W++ F +DTD+SGT++ E++ A+ GF L
Sbjct: 607 SMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHL 666
Query: 137 SPQAVNSIAKRYS-TNGKITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCV 195
+ Q + I RY+ + I FD +I C V+L + +F D G++ +++Q
Sbjct: 667 NNQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLT 726
Query: 196 M 196
M
Sbjct: 727 M 727
>gi|14161692 calpain small subunit 2 [Homo sapiens]
Length = 248
Score = 99.0 bits (245), Expect = 2e-21
Identities = 52/164 (31%), Positives = 94/164 (57%), Gaps = 8/164 (4%)
Query: 39 FAAVAGQDGQIDADELQRCLTQSGIAGGYKP-----FNLETCRLMVSMLDRDMSGTMGFN 93
F +AG D ++ A +L L + + +K F+L+TCR +VS++D D +G +GF
Sbjct: 85 FTQLAGPDMEVGATDLMNILNK--VLSKHKDLKTDGFSLDTCRSIVSVMDSDTTGKLGFE 142
Query: 94 EFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYST-NG 152
EFK LW + W+ + +D D SG++ +L+ AL GF+L+ Q I +RY+ +G
Sbjct: 143 EFKYLWNNIKKWQCVYKQYDRDHSGSLGSSQLRGALQAAGFQLNEQLYQMIVRRYANEDG 202
Query: 153 KITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVM 196
+ F+++I+C V+L A+ +F+ D + G++ +++Q M
Sbjct: 203 DMDFNNFISCLVRLDAMFRAFKSLDRDRDGLIQVSIKEWLQLTM 246
>gi|221554549 calpain 8 [Homo sapiens]
Length = 703
Score = 98.6 bits (244), Expect = 3e-21
Identities = 57/176 (32%), Positives = 94/176 (53%), Gaps = 4/176 (2%)
Query: 25 PAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLTQSGIAGG---YKPFNLETCRLMVSM 81
P+ Q D F +AG+D +I A+ L+ L ++ + FN+ TCR M+S+
Sbjct: 527 PSEVDQEDDQFRRLFEKLAGKDSEITANALKILLNEAFSKRTDIKFDGFNINTCREMISL 586
Query: 82 LDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAV 141
LD + +GT+G EFK LW + + + + D + SGT+D E++ AL GF L+ Q
Sbjct: 587 LDSNGTGTLGAVEFKTLWLKIQKYLEIYWETDYNHSGTIDAHEMRTALRKAGFTLNSQVQ 646
Query: 142 NSIAKRYSTNG-KITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVM 196
+IA RY+ + I FD ++AC ++L L F D + G+V +++ CV+
Sbjct: 647 QTIALRYACSKLGINFDSFVACMIRLETLFKLFSLLDEDKDGMVQLSLAEWLCCVL 702
>gi|12408656 calpain 1, large subunit [Homo sapiens]
Length = 714
Score = 94.7 bits (234), Expect = 4e-20
Identities = 55/164 (33%), Positives = 90/164 (54%), Gaps = 8/164 (4%)
Query: 39 FAAVAGQDGQIDADELQRCLTQSGIAGGYKP-----FNLETCRLMVSMLDRDMSGTMGFN 93
F +AG+D +I EL+ L + I +K F+LE+CR MV+++DRD +G +G
Sbjct: 551 FRQLAGEDMEISVKELRTILNR--IISKHKDLRTKGFSLESCRSMVNLMDRDGNGKLGLV 608
Query: 94 EFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYS-TNG 152
EF LW + + F FD D+SG++ E++ A+ + GF+L+ + I RYS +
Sbjct: 609 EFNILWNRIRNYLSIFRKFDLDKSGSMSAYEMRMAIESAGFKLNKKLYELIITRYSEPDL 668
Query: 153 KITFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVM 196
+ FD+++ C V+L + F+ DT GVV F ++Q M
Sbjct: 669 AVDFDNFVCCLVRLETMFRFFKTLDTDLDGVVTFDLFKWLQLTM 712
>gi|7705383 calpain 9 isoform 2 [Homo sapiens]
Length = 664
Score = 94.4 bits (233), Expect = 6e-20
Identities = 52/164 (31%), Positives = 89/164 (54%), Gaps = 4/164 (2%)
Query: 39 FAAVAGQDGQIDADELQRCLT---QSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEF 95
F VAG+D ++ A+EL+ L Q +K +L +C+ ++S++D +G + F+EF
Sbjct: 501 FEQVAGEDMEVTAEELEYVLNAVLQKKKDIKFKKLSLISCKNIISLMDTSGNGKLEFDEF 560
Query: 96 KELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNG-KI 154
K W L W F+ FD D+SGT+ EL+ AL GF+LS + I RY+ ++
Sbjct: 561 KVFWDKLKQWINLFLRFDADKSGTMSTYELRTALKAAGFQLSSHLLQLIVLRYADEELQL 620
Query: 155 TFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVMSV 198
FDD++ C V+L + F+ T + ++ ++FI M++
Sbjct: 621 DFDDFLNCLVRLENASRVFQALSTKNKEFIHLNINEFIHLTMNI 664
>gi|5729758 calpain 9 isoform 1 [Homo sapiens]
Length = 690
Score = 94.4 bits (233), Expect = 6e-20
Identities = 52/164 (31%), Positives = 89/164 (54%), Gaps = 4/164 (2%)
Query: 39 FAAVAGQDGQIDADELQRCLT---QSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEF 95
F VAG+D ++ A+EL+ L Q +K +L +C+ ++S++D +G + F+EF
Sbjct: 527 FEQVAGEDMEVTAEELEYVLNAVLQKKKDIKFKKLSLISCKNIISLMDTSGNGKLEFDEF 586
Query: 96 KELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNG-KI 154
K W L W F+ FD D+SGT+ EL+ AL GF+LS + I RY+ ++
Sbjct: 587 KVFWDKLKQWINLFLRFDADKSGTMSTYELRTALKAAGFQLSSHLLQLIVLRYADEELQL 646
Query: 155 TFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVMSV 198
FDD++ C V+L + F+ T + ++ ++FI M++
Sbjct: 647 DFDDFLNCLVRLENASRVFQALSTKNKEFIHLNINEFIHLTMNI 690
>gi|157389005 calpain 2 isoform 1 [Homo sapiens]
Length = 700
Score = 94.0 bits (232), Expect = 8e-20
Identities = 55/153 (35%), Positives = 85/153 (55%), Gaps = 10/153 (6%)
Query: 39 FAAVAGQDGQIDADELQRCLT------QSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGF 92
FA +AG+D +I A ELQ L Q + G F++ETC++MV MLD D SG +G
Sbjct: 538 FAQLAGEDAEISAFELQTILRRVLAKRQDIKSDG---FSIETCKIMVDMLDSDGSGKLGL 594
Query: 93 NEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNG 152
EF LW + +++ + D DRSGT++ E++KAL GF++ Q I R++ +
Sbjct: 595 KEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQ 654
Query: 153 K-ITFDDYIACCVKLRALTDSFRRRDTAQQGVV 184
I FD+++ C V+L L F++ D G +
Sbjct: 655 LIIDFDNFVRCLVRLETLFKIFKQLDPENTGTI 687
>gi|225703100 calpain 2 isoform 2 [Homo sapiens]
Length = 622
Score = 94.0 bits (232), Expect = 8e-20
Identities = 55/153 (35%), Positives = 85/153 (55%), Gaps = 10/153 (6%)
Query: 39 FAAVAGQDGQIDADELQRCLT------QSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGF 92
FA +AG+D +I A ELQ L Q + G F++ETC++MV MLD D SG +G
Sbjct: 460 FAQLAGEDAEISAFELQTILRRVLAKRQDIKSDG---FSIETCKIMVDMLDSDGSGKLGL 516
Query: 93 NEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNG 152
EF LW + +++ + D DRSGT++ E++KAL GF++ Q I R++ +
Sbjct: 517 KEFYILWTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQ 576
Query: 153 K-ITFDDYIACCVKLRALTDSFRRRDTAQQGVV 184
I FD+++ C V+L L F++ D G +
Sbjct: 577 LIIDFDNFVRCLVRLETLFKIFKQLDPENTGTI 609
>gi|27765080 calpain 3 isoform e [Homo sapiens]
Length = 156
Score = 92.0 bits (227), Expect = 3e-19
Identities = 50/155 (32%), Positives = 84/155 (54%), Gaps = 8/155 (5%)
Query: 48 QIDADELQRCLTQSGIAGGYKP-----FNLETCRLMVSMLDRDMSGTMGFNEFKELWAVL 102
+I ADEL++ L + +K F LE+CR M++++D D SG + EF LW +
Sbjct: 2 EICADELKKVLNT--VVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKI 59
Query: 103 NGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYS-TNGKITFDDYIA 161
W++ F +DTD+SGT++ E++ A+ GF L+ Q + I RY+ + I FD +I
Sbjct: 60 KAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFIC 119
Query: 162 CCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVM 196
C V+L + +F D G++ +++Q M
Sbjct: 120 CFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTM 154
>gi|27765078 calpain 3 isoform e [Homo sapiens]
Length = 156
Score = 92.0 bits (227), Expect = 3e-19
Identities = 50/155 (32%), Positives = 84/155 (54%), Gaps = 8/155 (5%)
Query: 48 QIDADELQRCLTQSGIAGGYKP-----FNLETCRLMVSMLDRDMSGTMGFNEFKELWAVL 102
+I ADEL++ L + +K F LE+CR M++++D D SG + EF LW +
Sbjct: 2 EICADELKKVLNT--VVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKI 59
Query: 103 NGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYS-TNGKITFDDYIA 161
W++ F +DTD+SGT++ E++ A+ GF L+ Q + I RY+ + I FD +I
Sbjct: 60 KAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFIC 119
Query: 162 CCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVM 196
C V+L + +F D G++ +++Q M
Sbjct: 120 CFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTM 154
>gi|215490104 calpain 11 [Homo sapiens]
Length = 739
Score = 90.5 bits (223), Expect = 8e-19
Identities = 51/162 (31%), Positives = 84/162 (51%), Gaps = 4/162 (2%)
Query: 39 FAAVAGQDGQIDADELQRCLTQSGI---AGGYKPFNLETCRLMVSMLDRDMSGTMGFNEF 95
F VAG+ +I ELQR L + I + K F L+ CR M++++D+D SG +G EF
Sbjct: 576 FKIVAGEGKEIGVYELQRLLNRMAIKFKSFKTKGFGLDACRCMINLMDKDGSGKLGLLEF 635
Query: 96 KELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNGK-I 154
K LW L W F D D SGT++ E++ + G +L+ + + + RY+ + I
Sbjct: 636 KILWKKLKKWMDIFRECDQDHSGTLNSYEMRLVIEKAGIKLNNKVMQVLVARYADDDLII 695
Query: 155 TFDDYIACCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVM 196
FD +I+C ++L+ + F D G + + ++Q M
Sbjct: 696 DFDSFISCFLRLKTMFTFFLTMDPKNTGHICLSLEQWLQMTM 737
>gi|38707981 calpain 12 [Homo sapiens]
Length = 719
Score = 63.2 bits (152), Expect = 1e-10
Identities = 36/137 (26%), Positives = 67/137 (48%), Gaps = 8/137 (5%)
Query: 39 FAAVAGQDGQIDADELQRCLTQS-----GIAGGYKPFNLETCRLMVSMLDRDMSGTMGFN 93
F +AG++ +++A +LQ L+ + + L TC ++ S + +
Sbjct: 556 FQELAGEEEELNASQLQALLSIALEPARAHTSTPREIGLRTCEQLLQCFGHGQS--LALH 613
Query: 94 EFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRY-STNG 152
F++LW L W+ F FD D SGT++ EL+ AL GF L+ Q ++ RY +
Sbjct: 614 HFQQLWGYLLEWQAIFNKFDEDTSGTMNSYELRLALNAAGFHLNNQLTQTLTSRYRDSRL 673
Query: 153 KITFDDYIACCVKLRAL 169
++ F+ +++C L +
Sbjct: 674 RVDFERFVSCVAHLTCI 690
>gi|41152101 calpain 13 [Homo sapiens]
Length = 669
Score = 53.5 bits (127), Expect = 1e-07
Identities = 44/167 (26%), Positives = 78/167 (46%), Gaps = 11/167 (6%)
Query: 23 GGPAFPGQTQDPLYGYFAAVAGQDGQIDADELQRCLTQSGIAGGYKP-FNLETCRLMVSM 81
G P+ G Q F A Q IDA +LQ L Q + G F+L+ CR +V++
Sbjct: 494 GSPSEHGSQQS----IFNRYAQQRLDIDATQLQGLLNQELLTGPPGDMFSLDECRSLVAL 549
Query: 82 LDRDMSGTMGFNEFKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTT----MGFRLS 137
++ ++G + EF LW L ++ F T G + +L KA+ G +S
Sbjct: 550 MELKVNGRLDQEEFARLWKRLVHYQHVFQKVQTS-PGVLLSSDLWKAIENTDFLRGIFIS 608
Query: 138 PQAVNSIAKRYSTN-GKITFDDYIACCVKLRALTDSFRRRDTAQQGV 183
+ ++ + RYS + G+++F + ++L A+ +FR +G+
Sbjct: 609 RELLHLVTLRYSDSVGRVSFPSLVCFLMRLEAMAKTFRNLSKDGKGL 655
>gi|223468608 calpain 14 [Homo sapiens]
Length = 684
Score = 51.6 bits (122), Expect = 4e-07
Identities = 39/150 (26%), Positives = 72/150 (48%), Gaps = 5/150 (3%)
Query: 38 YFAAVAGQDGQIDADELQRCLTQ---SGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNE 94
+F + +I+A +LQ L Q S + F+LE C+ ++++LD + SGTM E
Sbjct: 522 FFTKFFEKHPEINAVQLQNLLNQMTWSSLGSRQPFFSLEACQGILALLDLNASGTMSIQE 581
Query: 95 FKELWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRY-STNGK 153
F++LW L ++ F D SG ++ ++L A+ G LS + RY +
Sbjct: 582 FRDLWKQLKLSQKVFHKQDRG-SGYLNWEQLHAAMREAGIMLSDDVCQLMLIRYGGPRLQ 640
Query: 154 ITFDDYIACCVKLRALTDSFRRRDTAQQGV 183
+ F +I +++ + D F+ +G+
Sbjct: 641 MDFVSFIHLMLRVENMEDVFQNLTQDGKGI 670
>gi|4885111 calmodulin-like 3 [Homo sapiens]
Length = 149
Score = 45.1 bits (105), Expect = 4e-05
Identities = 32/108 (29%), Positives = 55/108 (50%), Gaps = 10/108 (9%)
Query: 66 GYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVL-------NGWRQHFISFDTDRSG 118
G P E R M+S +DRD +GT+ F EF + A R+ F FD D +G
Sbjct: 41 GQNPTEAEL-RDMMSEIDRDGNGTVDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNG 99
Query: 119 TVDPQELQKALTTMGFRLSPQAVNSIAKRYST--NGKITFDDYIACCV 164
V EL+ +T +G +LS + V+ + + T +G++ +++++ V
Sbjct: 100 FVSAAELRHVMTRLGEKLSDEEVDEMIRAADTDGDGQVNYEEFVRVLV 147
>gi|56699407 solute carrier family 25, member 25 isoform c [Homo
sapiens]
Length = 489
Score = 44.7 bits (104), Expect = 5e-05
Identities = 33/114 (28%), Positives = 52/114 (45%), Gaps = 7/114 (6%)
Query: 45 QDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKE-LWAVLN 103
QDG+ +A E + + + G + F + +V D+D+ G + F EF L
Sbjct: 48 QDGRAEATEKRPTILL--VVGPAEQFP----KKIVQAGDKDLDGQLDFEEFVHYLQDHEK 101
Query: 104 GWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNGKITFD 157
R F S D G +D QE+ ++L +G ++S Q I K NG +T D
Sbjct: 102 KLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQAEKILKSMDKNGTMTID 155
>gi|239755176 PREDICTED: similar to solute carrier family 25, member
25 isoform 2 [Homo sapiens]
Length = 469
Score = 43.5 bits (101), Expect = 1e-04
Identities = 25/76 (32%), Positives = 36/76 (47%), Gaps = 1/76 (1%)
Query: 83 DRDMSGTMGFNEFKE-LWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAV 141
D+D+ G + F EF L R F S D G +D QE+ ++L +G ++S Q
Sbjct: 60 DKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQA 119
Query: 142 NSIAKRYSTNGKITFD 157
I K NG +T D
Sbjct: 120 EKILKSMDKNGTMTID 135
>gi|239755174 PREDICTED: similar to solute carrier family 25, member
25 isoform 1 [Homo sapiens]
Length = 503
Score = 43.5 bits (101), Expect = 1e-04
Identities = 25/76 (32%), Positives = 36/76 (47%), Gaps = 1/76 (1%)
Query: 83 DRDMSGTMGFNEFKE-LWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAV 141
D+D+ G + F EF L R F S D G +D QE+ ++L +G ++S Q
Sbjct: 94 DKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQA 153
Query: 142 NSIAKRYSTNGKITFD 157
I K NG +T D
Sbjct: 154 EKILKSMDKNGTMTID 169
>gi|56699401 solute carrier family 25, member 25 isoform a [Homo
sapiens]
Length = 469
Score = 43.5 bits (101), Expect = 1e-04
Identities = 25/76 (32%), Positives = 36/76 (47%), Gaps = 1/76 (1%)
Query: 83 DRDMSGTMGFNEFKE-LWAVLNGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAV 141
D+D+ G + F EF L R F S D G +D QE+ ++L +G ++S Q
Sbjct: 60 DKDLDGQLDFEEFVHYLQDHEKKLRLVFKSLDKKNDGRIDAQEIMQSLRDLGVKISEQQA 119
Query: 142 NSIAKRYSTNGKITFD 157
I K NG +T D
Sbjct: 120 EKILKSMDKNGTMTID 135
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.139 0.440
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,948,413
Number of Sequences: 37866
Number of extensions: 439382
Number of successful extensions: 7361
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 173
Number of HSP's successfully gapped in prelim test: 91
Number of HSP's that attempted gapping in prelim test: 3227
Number of HSP's gapped (non-prelim): 3876
length of query: 198
length of database: 18,247,518
effective HSP length: 97
effective length of query: 101
effective length of database: 14,574,516
effective search space: 1472026116
effective search space used: 1472026116
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 59 (27.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.