Guide to the Human Genome
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Search of human proteins with 4506753

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4506753 RuvB-like 1 [Homo sapiens]
         (456 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4506753 RuvB-like 1 [Homo sapiens]                                 890   0.0  
gi|5730023 RuvB-like 2 [Homo sapiens]                                 375   e-104
gi|21327685 YME1-like 1 isoform 1 [Homo sapiens]                       46   8e-05
gi|7657689 YME1-like 1 isoform 3 [Homo sapiens]                        46   8e-05
gi|17865802 vacuolar protein sorting factor 4B [Homo sapiens]          45   1e-04
gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens]        44   2e-04
gi|157671927 spermatogenesis associated 5 [Homo sapiens]               44   2e-04
gi|7019569 vacuolar protein sorting factor 4A [Homo sapiens]           44   4e-04
gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]                  42   0.001
gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]                  42   0.001
gi|40806170 spastin isoform 2 [Homo sapiens]                           39   0.010
gi|4505725 peroxin1 [Homo sapiens]                                     39   0.010
gi|11875211 spastin isoform 1 [Homo sapiens]                           39   0.010
gi|40806173 spastic paraplegia 7 isoform 2 [Homo sapiens]              39   0.010
gi|4507173 spastic paraplegia 7 isoform 1 [Homo sapiens]               39   0.010
gi|6005942 valosin-containing protein [Homo sapiens]                   39   0.013
gi|5802970 AFG3 ATPase family gene 3-like 2 [Homo sapiens]             38   0.017
gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens]                38   0.017
gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens]                38   0.017
gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]             38   0.022
gi|11321607 thyroid hormone receptor interactor 13 [Homo sapiens]      37   0.028
gi|5901990 katanin p60 subunit A 1 [Homo sapiens]                      37   0.037
gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit ...    36   0.083
gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]            36   0.083
gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens]             36   0.083
gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo sapi...    36   0.083
gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens]    36   0.083
gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens]              36   0.083
gi|32528306 replication factor C large subunit [Homo sapiens]          35   0.11 
gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens]             35   0.11 

>gi|4506753 RuvB-like 1 [Homo sapiens]
          Length = 456

 Score =  890 bits (2300), Expect = 0.0
 Identities = 456/456 (100%), Positives = 456/456 (100%)

Query: 1   MKIEEVKSTTKTQRIASHSHVKGLGLDESGLAKQAASGLVGQENAREACGVIVELIKSKK 60
           MKIEEVKSTTKTQRIASHSHVKGLGLDESGLAKQAASGLVGQENAREACGVIVELIKSKK
Sbjct: 1   MKIEEVKSTTKTQRIASHSHVKGLGLDESGLAKQAASGLVGQENAREACGVIVELIKSKK 60

Query: 61  MAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAI 120
           MAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAI
Sbjct: 61  MAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAI 120

Query: 121 GLRIKETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLKLDPSIFESL 180
           GLRIKETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLKLDPSIFESL
Sbjct: 121 GLRIKETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLKLDPSIFESL 180

Query: 181 QKERVEAGDVIYIEANSGAVKRQGRCDTYATEFDLEAEEYVPLPKGDVHKKKEIIQDVTL 240
           QKERVEAGDVIYIEANSGAVKRQGRCDTYATEFDLEAEEYVPLPKGDVHKKKEIIQDVTL
Sbjct: 181 QKERVEAGDVIYIEANSGAVKRQGRCDTYATEFDLEAEEYVPLPKGDVHKKKEIIQDVTL 240

Query: 241 HDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLRGEINKVVNKYIDQGIAELVPGVLF 300
           HDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLRGEINKVVNKYIDQGIAELVPGVLF
Sbjct: 241 HDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLRGEINKVVNKYIDQGIAELVPGVLF 300

Query: 301 VDEVHMLDIECFTYLHRALESSIAPIVIFASNRGNCVIRGTEDITSPHGIPLDLLDRVMI 360
           VDEVHMLDIECFTYLHRALESSIAPIVIFASNRGNCVIRGTEDITSPHGIPLDLLDRVMI
Sbjct: 301 VDEVHMLDIECFTYLHRALESSIAPIVIFASNRGNCVIRGTEDITSPHGIPLDLLDRVMI 360

Query: 361 IRTMLYTPQEMKQIIKIRAQTEGINISEEALNHLGEIGTKTTLRYSVQLLTPANLLAKIN 420
           IRTMLYTPQEMKQIIKIRAQTEGINISEEALNHLGEIGTKTTLRYSVQLLTPANLLAKIN
Sbjct: 361 IRTMLYTPQEMKQIIKIRAQTEGINISEEALNHLGEIGTKTTLRYSVQLLTPANLLAKIN 420

Query: 421 GKDSIEKEHVEEISELFYDAKSSAKILADQQDKYMK 456
           GKDSIEKEHVEEISELFYDAKSSAKILADQQDKYMK
Sbjct: 421 GKDSIEKEHVEEISELFYDAKSSAKILADQQDKYMK 456


>gi|5730023 RuvB-like 2 [Homo sapiens]
          Length = 463

 Score =  375 bits (962), Expect = e-104
 Identities = 195/456 (42%), Positives = 301/456 (66%), Gaps = 15/456 (3%)

Query: 2   KIEEVKSTTKTQRIASHSHVKGLGLDESGLAKQAASGLVGQENAREACGVIVELIKSKKM 61
           K+ E++  T+ +RI +HSH++GLGLD++   +QA+ G+VGQ  AR A GV++E+I+  K+
Sbjct: 9   KVPEIRDVTRIERIGAHSHIRGLGLDDALEPRQASQGMVGQLAARRAAGVVLEMIREGKI 68

Query: 62  AGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAIG 121
           AGRAVL+AG PGTGKTA+A+ +AQ LG   PF  + GSE++S E+ KTE L + FRR+IG
Sbjct: 69  AGRAVLIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEIFSLEMSKTEALTQAFRRSIG 128

Query: 122 LRIKETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLKLDPSIFESLQ 181
           +RIKE  E+ EGEV E+   + + P  G G  +    + LKT +      L   + ESL 
Sbjct: 129 VRIKEETEIIEGEVVEI---QIDRPATGTGSKVGK--LTLKTTEMETIYDLGTKMIESLT 183

Query: 182 KERVEAGDVIYIEANSGAVKRQGRCDTYATEFDLEAEE--YVPLPKGDVHKKKEIIQDVT 239
           K++V+AGDVI I+  +G + + GR  T A ++D    +  +V  P G++ K+KE++  V+
Sbjct: 184 KDKVQAGDVITIDKATGKISKLGRSFTRARDYDAMGSQTKFVQCPDGELQKRKEVVHTVS 243

Query: 240 LHDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLRGEINKVVNKYIDQGIAELVPGVL 299
           LH++DV N+R QG          L      EI  ++R +IN  V ++ ++G AE++PGVL
Sbjct: 244 LHEIDVINSRTQG-------FLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVL 296

Query: 300 FVDEVHMLDIECFTYLHRALESSIAPIVIFASNRGNCVIRGTEDITSPHGIPLDLLDRVM 359
           F+DEVHMLDIE F++L+RALES +AP++I A+NRG   IRGT    SPHGIP+DLLDR++
Sbjct: 297 FIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGT-SYQSPHGIPIDLLDRLL 355

Query: 360 IIRTMLYTPQEMKQIIKIRAQTEGINISEEALNHLGEIGTKTTLRYSVQLLTPANLLAKI 419
           I+ T  Y+ ++ KQI++IR + E + +SE+A   L  IG +T+LRY++QL+T A+L+ + 
Sbjct: 356 IVSTTPYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQLITAASLVCRK 415

Query: 420 NGKDSIEKEHVEEISELFYDAKSSAKILADQQDKYM 455
                ++ + ++ +  LF D   S + + + QD ++
Sbjct: 416 RKGTEVQVDDIKRVYSLFLDESRSTQYMKEYQDAFL 451


>gi|21327685 YME1-like 1 isoform 1 [Homo sapiens]
          Length = 773

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 57/208 (27%), Positives = 91/208 (43%), Gaps = 45/208 (21%)

Query: 41  GQENAREACGVIVELIKSKK----MAGR---AVLLAGPPGTGKTALALAIAQELGSKVPF 93
           G E A++    +VE +K+ +    + G+    +LL GPPGTGKT LA A+A E  + VPF
Sbjct: 343 GVEEAKQELQEVVEFLKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGE--ADVPF 400

Query: 94  CPMVGSEVYSTEIKKTEVLMEN-FRRAIGLRIKETKEVYEGEVTELTPCETENPMGGYGK 152
               GSE     +      + N FR A   +      ++  E+  +     E+PM  Y +
Sbjct: 401 YYASGSEFDEMFVGVGASRIRNLFREA---KANAPCVIFIDELDSVGGKRIESPMHPYSR 457

Query: 153 -TISHVII---GLKTAKGTKQLKLDPSIFESLQKERVEAGDVIYIEANSGAVKRQGRCDT 208
            TI+ ++    G K  +G                  +  G   + EA   A+ R GR   
Sbjct: 458 QTINQLLAEMDGFKPNEGV-----------------IIIGATNFPEALDNALIRPGR--- 497

Query: 209 YATEFDLEAEEYVPLPKGDVHKKKEIIQ 236
               FD++    V +P+ DV  + EI++
Sbjct: 498 ----FDMQ----VTVPRPDVKGRTEILK 517


>gi|7657689 YME1-like 1 isoform 3 [Homo sapiens]
          Length = 716

 Score = 45.8 bits (107), Expect = 8e-05
 Identities = 57/208 (27%), Positives = 91/208 (43%), Gaps = 45/208 (21%)

Query: 41  GQENAREACGVIVELIKSKK----MAGR---AVLLAGPPGTGKTALALAIAQELGSKVPF 93
           G E A++    +VE +K+ +    + G+    +LL GPPGTGKT LA A+A E  + VPF
Sbjct: 286 GVEEAKQELQEVVEFLKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGE--ADVPF 343

Query: 94  CPMVGSEVYSTEIKKTEVLMEN-FRRAIGLRIKETKEVYEGEVTELTPCETENPMGGYGK 152
               GSE     +      + N FR A   +      ++  E+  +     E+PM  Y +
Sbjct: 344 YYASGSEFDEMFVGVGASRIRNLFREA---KANAPCVIFIDELDSVGGKRIESPMHPYSR 400

Query: 153 -TISHVII---GLKTAKGTKQLKLDPSIFESLQKERVEAGDVIYIEANSGAVKRQGRCDT 208
            TI+ ++    G K  +G                  +  G   + EA   A+ R GR   
Sbjct: 401 QTINQLLAEMDGFKPNEGV-----------------IIIGATNFPEALDNALIRPGR--- 440

Query: 209 YATEFDLEAEEYVPLPKGDVHKKKEIIQ 236
               FD++    V +P+ DV  + EI++
Sbjct: 441 ----FDMQ----VTVPRPDVKGRTEILK 460


>gi|17865802 vacuolar protein sorting factor 4B [Homo sapiens]
          Length = 444

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 35/116 (30%), Positives = 56/116 (48%), Gaps = 10/116 (8%)

Query: 37  SGLVGQENAREACGVIV-------ELIKSKKMAGRAVLLAGPPGTGKTALALAIAQELGS 89
           S + G E A+EA    V        L   K+   R +LL GPPGTGK+ LA A+A E  +
Sbjct: 134 SDVAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANN 193

Query: 90  KVPFCPMVGSEVYSTEIKKTEVLMENFRRAIGLRIKETKEVYEGEVTELTPCETEN 145
              F  +  S++ S  + ++E L++N  +    R  +   ++  E+  L    +EN
Sbjct: 194 ST-FFSISSSDLVSKWLGESEKLVKNLFQL--ARENKPSIIFIDEIDSLCGSRSEN 246


>gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens]
          Length = 753

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 52/179 (29%), Positives = 75/179 (41%), Gaps = 34/179 (18%)

Query: 64  RAVLLAGPPGTGKTALALAIAQELGSK---VPFCPMVGSEVYSTEIKKTEVLMENFRRAI 120
           R VLLAGPPG GKT L  A+A+E G++   V    + GS    TE    E +   F+RA 
Sbjct: 235 RGVLLAGPPGVGKTQLVRAVAREAGAELLAVSAPALQGSRPGETE----ENVRRVFQRAR 290

Query: 121 GLRIKETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLKLDPSIFESL 180
            L  +    ++  E+  L  C          + ++ V+  L  A G              
Sbjct: 291 ELASRGPSLLFLDEMDAL--CPQRGSRAPESRVVAQVLTLLDGASG-------------- 334

Query: 181 QKERVEAGDVIYIEANSGAVKRQGRCDTYATEFDLEAEEYVPLPKGDVHKKKEIIQDVT 239
            +E V  G     +A   A++R GR       FD E     P  K    ++KEI+Q +T
Sbjct: 335 DREVVVVGATNRPDALDPALRRPGR-------FDREVVIGTPTLK----QRKEILQVIT 382



 Score = 33.1 bits (74), Expect = 0.54
 Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 3/67 (4%)

Query: 54  ELIKSKKMAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTE-VL 112
           E ++      + VLL GPPG  KT L  A+A        F  + G++++S  +  +E VL
Sbjct: 489 EFVRMGLTQPKGVLLYGPPGCAKTTLVRALA--TSCHCSFVSVSGADLFSPFVGDSEKVL 546

Query: 113 MENFRRA 119
            + FR+A
Sbjct: 547 SQIFRQA 553


>gi|157671927 spermatogenesis associated 5 [Homo sapiens]
          Length = 893

 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 30/65 (46%), Positives = 39/65 (60%), Gaps = 4/65 (6%)

Query: 54  ELIKSKKM-AGRAVLLAGPPGTGKTALALAIAQELGSKVPFC--PMVGSEVY-STEIKKT 109
           EL KS  + A R VLL GPPGTGKT +A A+A E+G+ V     P + S+ Y  TE K  
Sbjct: 377 ELFKSYGIPAPRGVLLYGPPGTGKTMIARAVANEVGAYVSVINGPEIISKFYGETEAKLR 436

Query: 110 EVLME 114
           ++  E
Sbjct: 437 QIFAE 441



 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 52/186 (27%), Positives = 84/186 (45%), Gaps = 32/186 (17%)

Query: 64  RAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTE-VLMENFRRAIGL 122
           + VLL GPPG  KT +A A+A E G  + F  + G E+ +  + ++E  + E FR+A   
Sbjct: 662 KGVLLYGPPGCSKTMIAKALANESG--LNFLAIKGPELMNKYVGESERAVRETFRKA--- 716

Query: 123 RIKETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKT-AKGTKQLKLDPSIFESLQ 181
           R      ++  E+  L   E  + +G  G     V+  L T   G +QLK    +  + +
Sbjct: 717 RAVAPSIIFFDELDALA-VERGSSLGA-GNVADRVLAQLLTEMDGIEQLKDVTILAATNR 774

Query: 182 KERVEAGDVIYIEANSGAVKRQGRCDTYATEFDLEAEEYVPLPKGDVHKKKEIIQDVTLH 241
            +R++            A+ R GR D            YVPLP  D   ++EI + +  H
Sbjct: 775 PDRIDK-----------ALMRPGRIDRII---------YVPLP--DAATRREIFK-LQFH 811

Query: 242 DLDVAN 247
            + V+N
Sbjct: 812 SMPVSN 817


>gi|7019569 vacuolar protein sorting factor 4A [Homo sapiens]
          Length = 437

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 35/114 (30%), Positives = 53/114 (46%), Gaps = 10/114 (8%)

Query: 39  LVGQENAREACGVIV-------ELIKSKKMAGRAVLLAGPPGTGKTALALAIAQELGSKV 91
           + G E A+EA    V        L   K+   R +LL GPPGTGK+ LA A+A E  +  
Sbjct: 129 VAGLEGAKEALKEAVILPIKFPHLFTGKRTPWRGILLFGPPGTGKSYLAKAVATEANNST 188

Query: 92  PFCPMVGSEVYSTEIKKTEVLMENFRRAIGLRIKETKEVYEGEVTELTPCETEN 145
            F  +  S++ S  + ++E L++N       R  +   ++  EV  L     EN
Sbjct: 189 -FFSVSSSDLMSKWLGESEKLVKNLFEL--ARQHKPSIIFIDEVDSLCGSRNEN 239


>gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]
          Length = 750

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 30/106 (28%), Positives = 55/106 (51%), Gaps = 6/106 (5%)

Query: 66  VLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTE-VLMENFRRAIGLRI 124
           VLLAGPPG GKT LA A+A E G  + F  + G E+ +  + ++E  + + F+RA   + 
Sbjct: 512 VLLAGPPGCGKTLLAKAVANESG--LNFISVKGPELLNMYVGESERAVRQVFQRA---KN 566

Query: 125 KETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQL 170
                ++  EV  L P  ++   G   + ++ ++  +   +  +Q+
Sbjct: 567 SAPCVIFFDEVDALCPRRSDRETGASVRVVNQLLTEMDGLEARQQV 612



 Score = 37.7 bits (86), Expect = 0.022
 Identities = 26/58 (44%), Positives = 33/58 (56%), Gaps = 3/58 (5%)

Query: 64  RAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTE-VLMENFRRAI 120
           R VLL GPPG GKT LA AIA EL   +P   +   E+ S    ++E  L E F +A+
Sbjct: 193 RGVLLHGPPGCGKTLLAHAIAGEL--DLPILKVAAPEIVSGVSGESEQKLRELFEQAV 248


>gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]
          Length = 856

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 30/106 (28%), Positives = 55/106 (51%), Gaps = 6/106 (5%)

Query: 66  VLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTE-VLMENFRRAIGLRI 124
           VLLAGPPG GKT LA A+A E G  + F  + G E+ +  + ++E  + + F+RA   + 
Sbjct: 618 VLLAGPPGCGKTLLAKAVANESG--LNFISVKGPELLNMYVGESERAVRQVFQRA---KN 672

Query: 125 KETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQL 170
                ++  EV  L P  ++   G   + ++ ++  +   +  +Q+
Sbjct: 673 SAPCVIFFDEVDALCPRRSDRETGASVRVVNQLLTEMDGLEARQQV 718



 Score = 37.7 bits (86), Expect = 0.022
 Identities = 26/58 (44%), Positives = 33/58 (56%), Gaps = 3/58 (5%)

Query: 64  RAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTE-VLMENFRRAI 120
           R VLL GPPG GKT LA AIA EL   +P   +   E+ S    ++E  L E F +A+
Sbjct: 299 RGVLLHGPPGCGKTLLAHAIAGEL--DLPILKVAAPEIVSGVSGESEQKLRELFEQAV 354


>gi|40806170 spastin isoform 2 [Homo sapiens]
          Length = 584

 Score = 38.9 bits (89), Expect = 0.010
 Identities = 23/55 (41%), Positives = 30/55 (54%), Gaps = 7/55 (12%)

Query: 39  LVGQENAREACGVIV-------ELIKSKKMAGRAVLLAGPPGTGKTALALAIAQE 86
           + GQ+ A++A   IV       EL    +   R +LL GPPG GKT LA A+A E
Sbjct: 312 IAGQDLAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAE 366


>gi|4505725 peroxin1 [Homo sapiens]
          Length = 1283

 Score = 38.9 bits (89), Expect = 0.010
 Identities = 31/103 (30%), Positives = 51/103 (49%), Gaps = 8/103 (7%)

Query: 66  VLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRAIGLRIK 125
           +LL GPPGTGKT LA  IA+E  S++ F  + G E+ S  I  +E  +    R I +R +
Sbjct: 877 ILLYGPPGTGKTLLAGVIARE--SRMNFISVKGPELLSKYIGASEQAV----RDIFIRAQ 930

Query: 126 ETKE--VYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKG 166
             K   ++  E   + P    +  G   + ++ ++  L   +G
Sbjct: 931 AAKPCILFFDEFESIAPRRGHDNTGVTDRVVNQLLTQLDGVEG 973


>gi|11875211 spastin isoform 1 [Homo sapiens]
          Length = 616

 Score = 38.9 bits (89), Expect = 0.010
 Identities = 23/55 (41%), Positives = 30/55 (54%), Gaps = 7/55 (12%)

Query: 39  LVGQENAREACGVIV-------ELIKSKKMAGRAVLLAGPPGTGKTALALAIAQE 86
           + GQ+ A++A   IV       EL    +   R +LL GPPG GKT LA A+A E
Sbjct: 344 IAGQDLAKQALQEIVILPSLRPELFTGLRAPARGLLLFGPPGNGKTMLAKAVAAE 398


>gi|40806173 spastic paraplegia 7 isoform 2 [Homo sapiens]
          Length = 489

 Score = 38.9 bits (89), Expect = 0.010
 Identities = 20/37 (54%), Positives = 24/37 (64%), Gaps = 2/37 (5%)

Query: 64  RAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSE 100
           +  LL GPPG GKT LA A+A E  ++VPF  M G E
Sbjct: 343 KGALLLGPPGCGKTLLAKAVATE--AQVPFLAMAGPE 377


>gi|4507173 spastic paraplegia 7 isoform 1 [Homo sapiens]
          Length = 795

 Score = 38.9 bits (89), Expect = 0.010
 Identities = 20/37 (54%), Positives = 24/37 (64%), Gaps = 2/37 (5%)

Query: 64  RAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSE 100
           +  LL GPPG GKT LA A+A E  ++VPF  M G E
Sbjct: 343 KGALLLGPPGCGKTLLAKAVATE--AQVPFLAMAGPE 377


>gi|6005942 valosin-containing protein [Homo sapiens]
          Length = 806

 Score = 38.5 bits (88), Expect = 0.013
 Identities = 24/56 (42%), Positives = 33/56 (58%), Gaps = 5/56 (8%)

Query: 64  RAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLMENFRRA 119
           R +LL GPPGTGKT +A A+A E G+   F  + G E+ S    ++E    N R+A
Sbjct: 239 RGILLYGPPGTGKTLIARAVANETGAF--FFLINGPEIMSKLAGESE---SNLRKA 289



 Score = 32.3 bits (72), Expect = 0.91
 Identities = 16/33 (48%), Positives = 19/33 (57%)

Query: 54  ELIKSKKMAGRAVLLAGPPGTGKTALALAIAQE 86
           + +K      + VL  GPPG GKT LA AIA E
Sbjct: 502 KFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANE 534


>gi|5802970 AFG3 ATPase family gene 3-like 2 [Homo sapiens]
          Length = 797

 Score = 38.1 bits (87), Expect = 0.017
 Identities = 20/37 (54%), Positives = 24/37 (64%), Gaps = 2/37 (5%)

Query: 64  RAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSE 100
           +  +L GPPGTGKT LA A A E  + VPF  + GSE
Sbjct: 342 KGAILTGPPGTGKTLLAKATAGE--ANVPFITVSGSE 376


>gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens]
          Length = 490

 Score = 38.1 bits (87), Expect = 0.017
 Identities = 17/36 (47%), Positives = 23/36 (63%)

Query: 54  ELIKSKKMAGRAVLLAGPPGTGKTALALAIAQELGS 89
           +  K  +   + VL+ GPPGTGKT LA A+A E G+
Sbjct: 232 DFFKGIRRPWKGVLMVGPPGTGKTMLAKAVATECGT 267


>gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens]
          Length = 490

 Score = 38.1 bits (87), Expect = 0.017
 Identities = 17/36 (47%), Positives = 23/36 (63%)

Query: 54  ELIKSKKMAGRAVLLAGPPGTGKTALALAIAQELGS 89
           +  K  +   + VL+ GPPGTGKT LA A+A E G+
Sbjct: 232 DFFKGIRRPWKGVLMVGPPGTGKTMLAKAVATECGT 267


>gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]
          Length = 440

 Score = 37.7 bits (86), Expect = 0.022
 Identities = 19/38 (50%), Positives = 26/38 (68%), Gaps = 2/38 (5%)

Query: 64  RAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEV 101
           + V+L GPPGTGKT LA A+A +  +   F  +VGSE+
Sbjct: 220 KGVILYGPPGTGKTLLAKAVANQ--TSATFLRVVGSEL 255


>gi|11321607 thyroid hormone receptor interactor 13 [Homo sapiens]
          Length = 432

 Score = 37.4 bits (85), Expect = 0.028
 Identities = 17/24 (70%), Positives = 20/24 (83%)

Query: 64  RAVLLAGPPGTGKTALALAIAQEL 87
           R VLL GPPGTGKT+L  A+AQ+L
Sbjct: 173 RVVLLHGPPGTGKTSLCKALAQKL 196


>gi|5901990 katanin p60 subunit A 1 [Homo sapiens]
          Length = 491

 Score = 37.0 bits (84), Expect = 0.037
 Identities = 17/33 (51%), Positives = 21/33 (63%)

Query: 54  ELIKSKKMAGRAVLLAGPPGTGKTALALAIAQE 86
           E  K  +   + VL+ GPPGTGKT LA A+A E
Sbjct: 233 EFFKGIRRPWKGVLMVGPPGTGKTLLAKAVATE 265


>gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit 4
           [Homo sapiens]
          Length = 414

 Score = 35.8 bits (81), Expect = 0.083
 Identities = 24/65 (36%), Positives = 34/65 (52%), Gaps = 6/65 (9%)

Query: 40  VGQENAREACGVIVELIKSKKMAG----RAVLLAGPPGTGKTALALAIAQELGSKVPFCP 95
           + ++  REA  + +   +  K  G    R VL+ GPPG GKT LA A+A    +   F  
Sbjct: 168 IQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHH--TTAAFIR 225

Query: 96  MVGSE 100
           +VGSE
Sbjct: 226 VVGSE 230


>gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]
          Length = 980

 Score = 35.8 bits (81), Expect = 0.083
 Identities = 23/55 (41%), Positives = 33/55 (60%), Gaps = 3/55 (5%)

Query: 66  VLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEV-LMENFRRA 119
           +LL GPPGTGKT LA A+A E    + F  + G E+ +  + ++E  + E F RA
Sbjct: 740 LLLHGPPGTGKTLLAKAVATE--CSLTFLSVKGPELINMYVGQSEENVREVFARA 792



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 21/57 (36%), Positives = 27/57 (47%), Gaps = 4/57 (7%)

Query: 65  AVLLAGPPGTGKTALALAIAQELG---SKVPFCPMVGSEVYSTEIKKTEVLMENFRR 118
           +VLL GPPG GKT +  A    LG    KVP C  + +E       K + +    RR
Sbjct: 465 SVLLRGPPGCGKTTVVAAACSHLGLHLLKVP-CSSLCAESSGAVETKLQAIFSRARR 520


>gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens]
          Length = 406

 Score = 35.8 bits (81), Expect = 0.083
 Identities = 33/113 (29%), Positives = 52/113 (46%), Gaps = 9/113 (7%)

Query: 64  RAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEI-KKTEVLMENFRRAIGL 122
           + VLL GPPGTGKT LA A+A    +   F  + GSE+    I +   ++ E F  A   
Sbjct: 184 KGVLLYGPPGTGKTLLARAVAHH--TDCTFIRVSGSELVQKFIGEGARMVRELFVMA--- 238

Query: 123 RIKETKEVYEGEVTELTPCETENPMGG---YGKTISHVIIGLKTAKGTKQLKL 172
           R      ++  E+  +     E   GG     +T+  ++  L   + TK +K+
Sbjct: 239 REHAPSIIFMDEIDSIGSSRLEGGSGGDSEVQRTMLELLNQLDGFEATKNIKV 291


>gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo
           sapiens]
          Length = 387

 Score = 35.8 bits (81), Expect = 0.083
 Identities = 24/65 (36%), Positives = 34/65 (52%), Gaps = 6/65 (9%)

Query: 40  VGQENAREACGVIVELIKSKKMAG----RAVLLAGPPGTGKTALALAIAQELGSKVPFCP 95
           + ++  REA  + +   +  K  G    R VL+ GPPG GKT LA A+A    +   F  
Sbjct: 141 IQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHH--TTAAFIR 198

Query: 96  MVGSE 100
           +VGSE
Sbjct: 199 VVGSE 203


>gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens]
          Length = 418

 Score = 35.8 bits (81), Expect = 0.083
 Identities = 24/65 (36%), Positives = 34/65 (52%), Gaps = 6/65 (9%)

Query: 40  VGQENAREACGVIVELIKSKKMAG----RAVLLAGPPGTGKTALALAIAQELGSKVPFCP 95
           + ++  REA  + +   +  K  G    R VL+ GPPG GKT LA A+A    +   F  
Sbjct: 172 IQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHH--TTAAFIR 229

Query: 96  MVGSE 100
           +VGSE
Sbjct: 230 VVGSE 234


>gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens]
          Length = 433

 Score = 35.8 bits (81), Expect = 0.083
 Identities = 26/87 (29%), Positives = 43/87 (49%), Gaps = 6/87 (6%)

Query: 64  RAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEI-KKTEVLMENFRRAIGL 122
           + VLL GPPGTGKT  A A+A    +   F  ++GSE+    + +   ++ E F  A   
Sbjct: 210 KGVLLFGPPGTGKTLCARAVANR--TDACFIRVIGSELVQKYVGEGARMVRELFEMA--- 264

Query: 123 RIKETKEVYEGEVTELTPCETENPMGG 149
           R K+   ++  E+  +     ++  GG
Sbjct: 265 RTKKACLIFFDEIDAIGGARFDDGAGG 291


>gi|32528306 replication factor C large subunit [Homo sapiens]
          Length = 1147

 Score = 35.4 bits (80), Expect = 0.11
 Identities = 15/25 (60%), Positives = 18/25 (72%)

Query: 64  RAVLLAGPPGTGKTALALAIAQELG 88
           +A LL+GPPG GKT  A  + QELG
Sbjct: 644 KAALLSGPPGVGKTTTASLVCQELG 668


>gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens]
          Length = 439

 Score = 35.4 bits (80), Expect = 0.11
 Identities = 42/189 (22%), Positives = 80/189 (42%), Gaps = 31/189 (16%)

Query: 19  SHVKGLGLDESGLAKQAASGLVGQENAREACGVIVELIKSKKMAG------RAVLLAGPP 72
           S VK + +DE    + +  G + ++       +++ +   +K         + VL+ GPP
Sbjct: 170 SRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMYGPP 229

Query: 73  GTGKTALALAIAQELGSKVPFCPMVGSEVYSTEI----------------KKTEVLMENF 116
           GTGKT LA A A +  +K  F  + G ++    I                K   ++  + 
Sbjct: 230 GTGKTLLARACAAQ--TKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFIDE 287

Query: 117 RRAIGLRIKETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLK-LDPS 175
             AIG +  ++++  + EV + T  E  N + G+          +K    T ++  LDP+
Sbjct: 288 LDAIGTKRFDSEKAGDREV-QRTMLELLNQLDGFQPNTQ-----VKVIAATNRVDILDPA 341

Query: 176 IFESLQKER 184
           +  S + +R
Sbjct: 342 LLRSGRLDR 350


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.133    0.368 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,661,373
Number of Sequences: 37866
Number of extensions: 658377
Number of successful extensions: 1464
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 75
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 1358
Number of HSP's gapped (non-prelim): 114
length of query: 456
length of database: 18,247,518
effective HSP length: 106
effective length of query: 350
effective length of database: 14,233,722
effective search space: 4981802700
effective search space used: 4981802700
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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