Search of human proteins with 4506209

Search of human proteins with 4506209

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens]
         (433 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens]             863   0.0  
gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens]            347   1e-95
gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens]           323   1e-88
gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]            314   9e-86
gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens]            296   3e-80
gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit ...   285   6e-77
gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo sapi...   285   6e-77
gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens]   285   6e-77
gi|169167838 PREDICTED: similar to hCG2002932 [Homo sapiens]          252   4e-67
gi|239748566 PREDICTED: similar to hCG2002932 [Homo sapiens]          252   4e-67
gi|239742549 PREDICTED: hypothetical protein LOC345645 [Homo sap...   252   4e-67
gi|5802970 AFG3 ATPase family gene 3-like 2 [Homo sapiens]            210   2e-54
gi|6005942 valosin-containing protein [Homo sapiens]                  208   9e-54
gi|157671927 spermatogenesis associated 5 [Homo sapiens]              203   2e-52
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]     183   2e-46
gi|4507173 spastic paraplegia 7 isoform 1 [Homo sapiens]              182   4e-46
gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens]   181   1e-45
gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]                 176   5e-44
gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]                 176   5e-44
gi|21327685 YME1-like 1 isoform 1 [Homo sapiens]                      173   2e-43
gi|7657689 YME1-like 1 isoform 3 [Homo sapiens]                       173   2e-43
gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens]       168   1e-41
gi|4505725 peroxin1 [Homo sapiens]                                    159   4e-39
gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]           159   5e-39
gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens]               151   1e-36
gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens]               151   1e-36
gi|5901990 katanin p60 subunit A 1 [Homo sapiens]                     147   1e-35
gi|31742536 fidgetin-like 1 [Homo sapiens]                            139   4e-33
gi|112789543 fidgetin-like 1 [Homo sapiens]                           139   4e-33
gi|17865802 vacuolar protein sorting factor 4B [Homo sapiens]         131   1e-30

>gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens]
          Length = 433

 Score =  863 bits (2230), Expect = 0.0
 Identities = 433/433 (100%), Positives = 433/433 (100%)

Query: 1   MPDYLGADQRKTKEDEKDDKPIRALDEGDIALLKTYGQSTYSRQIKQVEDDIQQLLKKIN 60
           MPDYLGADQRKTKEDEKDDKPIRALDEGDIALLKTYGQSTYSRQIKQVEDDIQQLLKKIN
Sbjct: 1   MPDYLGADQRKTKEDEKDDKPIRALDEGDIALLKTYGQSTYSRQIKQVEDDIQQLLKKIN 60

Query: 61  ELTGIKESDTGLAPPALWDLAADKQTLQSEQPLQVARCTKIINADSEDPKYIINVKQFAK 120
           ELTGIKESDTGLAPPALWDLAADKQTLQSEQPLQVARCTKIINADSEDPKYIINVKQFAK
Sbjct: 61  ELTGIKESDTGLAPPALWDLAADKQTLQSEQPLQVARCTKIINADSEDPKYIINVKQFAK 120

Query: 121 FVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGC 180
           FVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGC
Sbjct: 121 FVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGC 180

Query: 181 KEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRV 240
           KEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRV
Sbjct: 181 KEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRV 240

Query: 241 IGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTML 300
           IGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTML
Sbjct: 241 IGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTML 300

Query: 301 ELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHAR 360
           ELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHAR
Sbjct: 301 ELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHAR 360

Query: 361 SMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSY 420
           SMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSY
Sbjct: 361 SMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSY 420

Query: 421 AKFSATPRYMTYN 433
           AKFSATPRYMTYN
Sbjct: 421 AKFSATPRYMTYN 433


>gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens]
          Length = 406

 Score =  347 bits (890), Expect = 1e-95
 Identities = 174/309 (56%), Positives = 224/309 (72%)

Query: 110 KYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEK 169
           K ++ V    KFVVD+   +   D+    RV +  + Y +H  LP K+DP V++M VE+ 
Sbjct: 84  KVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMMVEKV 143

Query: 170 PDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAV 229
           PD TY  +GG  +QI++++EV+E P+ HPE F  LGI  PKGVLL+GPPGTGKTL ARAV
Sbjct: 144 PDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLLARAV 203

Query: 230 ANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGA 289
           A+ TD  FIRV GSELVQK++GEGARMVRELF MAR     +IF DEID+IG +R + G+
Sbjct: 204 AHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRLEGGS 263

Query: 290 GGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLE 349
           GGD+EVQRTMLEL+NQLDGF+   NIKV+MATNR D LD AL+RPGR+DRKIEF  P+ E
Sbjct: 264 GGDSEVQRTMLELLNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEFPPPNEE 323

Query: 350 GRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDF 409
            R  I KIH+R M++ R I    +A L P ++GAE++ VCTEAGM+A+R RR   T++DF
Sbjct: 324 ARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVHVTQEDF 383

Query: 410 LEAVNKVIK 418
             AV KV++
Sbjct: 384 EMAVAKVMQ 392


>gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens]
          Length = 403

 Score =  323 bits (829), Expect = 1e-88
 Identities = 167/374 (44%), Positives = 238/374 (63%), Gaps = 16/374 (4%)

Query: 46  KQVEDDIQQLLKKINELTGIKESDTGLAPPALWDLAADKQTLQSEQPLQVARCTKIINAD 105
           K+++  +++L +++ ELT   E               D + LQS     V +    +   
Sbjct: 34  KEIDGRLKELREQLKELTKQYEKSEN-----------DLKALQS-----VGQIVGEVLKQ 77

Query: 106 SEDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQ 165
             + K+I+      ++VV    Q+  + ++ G RV +D     I   LP ++DP V  M 
Sbjct: 78  LTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLVYNMS 137

Query: 166 VEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLC 225
            E+  +V+YS++GG  EQI +LREV+E PL +PE F  +GI PPKG LL+GPPGTGKTL 
Sbjct: 138 HEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLL 197

Query: 226 ARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARF 285
           ARAVA++ D  F++V+ S +V KY+GE AR++RE+F  AR  + C+IF DEIDAIGG RF
Sbjct: 198 ARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRF 257

Query: 286 DDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSL 345
            +G   D E+QRT++EL+NQ+DGFD    +K++MATNRPDTLDPAL+RPGRLDRKI   L
Sbjct: 258 SEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDL 317

Query: 346 PDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIAT 405
           P+ + R  I KIHA  ++   +I +E + +L     GA++R+VCTEAGMFAIRA      
Sbjct: 318 PNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVV 377

Query: 406 EKDFLEAVNKVIKS 419
           ++DF++AV KV  S
Sbjct: 378 QEDFMKAVRKVADS 391


>gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]
          Length = 440

 Score =  314 bits (805), Expect = 9e-86
 Identities = 159/336 (47%), Positives = 228/336 (67%), Gaps = 6/336 (1%)

Query: 92  PLQVARCTKIINADSEDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHI 151
           P+ V    +II    +D   I++    ++  V +   V    +E G  V ++   + +  
Sbjct: 106 PMSVGTLEEII----DDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIG 161

Query: 152 PLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKG 211
            L    DP VT+M+VE+ P  TY+D+GG   QI++++E VE PL HPE +  +GI+PPKG
Sbjct: 162 VLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKG 221

Query: 212 VLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACL 271
           V+L+GPPGTGKTL A+AVAN+T A F+RV+GSEL+QKY+G+G ++VRELF +A      +
Sbjct: 222 VILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSI 281

Query: 272 IFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPAL 331
           +F DEIDAIG  R+D  +GG+ E+QRTMLEL+NQLDGFD RG++KV+MATNR +TLDPAL
Sbjct: 282 VFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPAL 341

Query: 332 MRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTE 391
           +RPGR+DRKIEF LPD + +  IF+IH   M++  D+  + L     + +GA+I+++CTE
Sbjct: 342 IRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTE 401

Query: 392 AGMFAIRARRKIATEKDFLEAVNKVIKSYAKFSATP 427
           AG+ A+R RR   T +DF ++   V+  Y K   TP
Sbjct: 402 AGLMALRERRMKVTNEDFKKSKENVL--YKKQEGTP 435


>gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens]
          Length = 439

 Score =  296 bits (757), Expect = 3e-80
 Identities = 144/283 (50%), Positives = 199/283 (70%)

Query: 134 IEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVET 193
           ++ G  VGV+++ Y I   LP + D  V  M+V+E+P   YSD+GG  +QI++L E +  
Sbjct: 145 LKPGDLVGVNKDSYLILETLPTEYDSRVKAMEVDERPTEQYSDIGGLDKQIQELVEAIVL 204

Query: 194 PLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEG 253
           P+ H E+F NLGI+PPKGVL++GPPGTGKTL ARA A +T A F+++ G +LVQ ++G+G
Sbjct: 205 PMNHKEKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLKLAGPQLVQMFIGDG 264

Query: 254 ARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRG 313
           A++VR+ F +A+ K   +IF DE+DAIG  RFD    GD EVQRTMLEL+NQLDGF P  
Sbjct: 265 AKLVRDAFALAKEKAPSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQLDGFQPNT 324

Query: 314 NIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELL 373
            +KV+ ATNR D LDPAL+R GRLDRKIEF +P+ E R  I +IH+R M+V  D+ +E L
Sbjct: 325 QVKVIAATNRVDILDPALLRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNYEEL 384

Query: 374 ARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKV 416
           AR   +  GA+ ++VC EAGM A+R      T +D++E + +V
Sbjct: 385 ARCTDDFNGAQCKAVCVEAGMIALRRGATELTHEDYMEGILEV 427


>gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit 4
           [Homo sapiens]
          Length = 414

 Score =  285 bits (729), Expect = 6e-77
 Identities = 140/266 (52%), Positives = 184/266 (69%)

Query: 153 LPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGV 212
           LPP+ D ++ M+  ++KPDV Y+D+GG   Q +++RE VE PL H E +  +GI+PP+GV
Sbjct: 139 LPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGV 198

Query: 213 LLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLI 272
           L++GPPG GKT+ A+AVA+ T A FIRV+GSE VQKY+GEG RMVR++F +A+     +I
Sbjct: 199 LMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAII 258

Query: 273 FFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALM 332
           F DEIDAI   RFD   G D EVQR +LEL+NQ+DGFD   N+KV+MATNR DTLDPAL+
Sbjct: 259 FIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALL 318

Query: 333 RPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEA 392
           RPGRLDRKIEF LPD   +  IF      M++  ++  E         +GA+I S+C E+
Sbjct: 319 RPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQES 378

Query: 393 GMFAIRARRKIATEKDFLEAVNKVIK 418
           GM A+R  R I   KDF +A   VIK
Sbjct: 379 GMLAVRENRYIVLAKDFEKAYKTVIK 404


>gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo
           sapiens]
          Length = 387

 Score =  285 bits (729), Expect = 6e-77
 Identities = 140/266 (52%), Positives = 184/266 (69%)

Query: 153 LPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGV 212
           LPP+ D ++ M+  ++KPDV Y+D+GG   Q +++RE VE PL H E +  +GI+PP+GV
Sbjct: 112 LPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGV 171

Query: 213 LLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLI 272
           L++GPPG GKT+ A+AVA+ T A FIRV+GSE VQKY+GEG RMVR++F +A+     +I
Sbjct: 172 LMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAII 231

Query: 273 FFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALM 332
           F DEIDAI   RFD   G D EVQR +LEL+NQ+DGFD   N+KV+MATNR DTLDPAL+
Sbjct: 232 FIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALL 291

Query: 333 RPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEA 392
           RPGRLDRKIEF LPD   +  IF      M++  ++  E         +GA+I S+C E+
Sbjct: 292 RPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQES 351

Query: 393 GMFAIRARRKIATEKDFLEAVNKVIK 418
           GM A+R  R I   KDF +A   VIK
Sbjct: 352 GMLAVRENRYIVLAKDFEKAYKTVIK 377


>gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens]
          Length = 418

 Score =  285 bits (729), Expect = 6e-77
 Identities = 140/266 (52%), Positives = 184/266 (69%)

Query: 153 LPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGV 212
           LPP+ D ++ M+  ++KPDV Y+D+GG   Q +++RE VE PL H E +  +GI+PP+GV
Sbjct: 143 LPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGV 202

Query: 213 LLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLI 272
           L++GPPG GKT+ A+AVA+ T A FIRV+GSE VQKY+GEG RMVR++F +A+     +I
Sbjct: 203 LMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAII 262

Query: 273 FFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALM 332
           F DEIDAI   RFD   G D EVQR +LEL+NQ+DGFD   N+KV+MATNR DTLDPAL+
Sbjct: 263 FIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALL 322

Query: 333 RPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEA 392
           RPGRLDRKIEF LPD   +  IF      M++  ++  E         +GA+I S+C E+
Sbjct: 323 RPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQES 382

Query: 393 GMFAIRARRKIATEKDFLEAVNKVIK 418
           GM A+R  R I   KDF +A   VIK
Sbjct: 383 GMLAVRENRYIVLAKDFEKAYKTVIK 408


>gi|169167838 PREDICTED: similar to hCG2002932 [Homo sapiens]
          Length = 415

 Score =  252 bits (644), Expect = 4e-67
 Identities = 126/287 (43%), Positives = 192/287 (66%), Gaps = 21/287 (7%)

Query: 146 KYQIHIPLPPKID---PTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFV 202
           ++++H  +   +D   P VTMM+VE+ P  TY + GG   QI++++E +E PL HPE + 
Sbjct: 140 RHKVHAVIGVLMDDTGPLVTMMKVEKAPQETYVNTGGLDNQIQEIKESMELPLPHPEYYE 199

Query: 203 NLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFE 262
            +G +PPKGV+L GPPGT              A F+RV+GSEL+QKY+G+G ++VR++F+
Sbjct: 200 EMGTKPPKGVILCGPPGT--------------ATFLRVVGSELIQKYLGDGPKLVRQVFQ 245

Query: 263 MARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLEL--INQLDGFDPRGNIKVLMA 320
           +A      ++F DEI+AIG  R+D  +GG+ E+Q+TMLEL  +NQL GFD R ++KV+MA
Sbjct: 246 VAEEHAPSIMFTDEIEAIGTKRYDSNSGGEREIQQTMLELELLNQLGGFDSREDVKVIMA 305

Query: 321 TNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNS 380
           T + +TLDP L+RPGR+D+KIEF LPD + + HIF+IH   M++  D+  + L     + 
Sbjct: 306 TKQVETLDPVLIRPGRIDKKIEFHLPDEKTKKHIFQIHTSRMTLANDVTLDDLIMAKDDF 365

Query: 381 TGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYAKFSATP 427
           +GA+I+++CTEAG+ A+R  R  AT +DF +++  V+  Y K    P
Sbjct: 366 SGADIKAICTEAGLMALREHRMKATNEDFKKSIESVL--YKKHEGIP 410


>gi|239748566 PREDICTED: similar to hCG2002932 [Homo sapiens]
          Length = 415

 Score =  252 bits (644), Expect = 4e-67
 Identities = 126/287 (43%), Positives = 192/287 (66%), Gaps = 21/287 (7%)

Query: 146 KYQIHIPLPPKID---PTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFV 202
           ++++H  +   +D   P VTMM+VE+ P  TY + GG   QI++++E +E PL HPE + 
Sbjct: 140 RHKVHAVIGVLMDDTGPLVTMMKVEKAPQETYVNTGGLDNQIQEIKESMELPLPHPEYYE 199

Query: 203 NLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFE 262
            +G +PPKGV+L GPPGT              A F+RV+GSEL+QKY+G+G ++VR++F+
Sbjct: 200 EMGTKPPKGVILCGPPGT--------------ATFLRVVGSELIQKYLGDGPKLVRQVFQ 245

Query: 263 MARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLEL--INQLDGFDPRGNIKVLMA 320
           +A      ++F DEI+AIG  R+D  +GG+ E+Q+TMLEL  +NQL GFD R ++KV+MA
Sbjct: 246 VAEEHAPSIMFTDEIEAIGTKRYDSNSGGEREIQQTMLELELLNQLGGFDSREDVKVIMA 305

Query: 321 TNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNS 380
           T + +TLDP L+RPGR+D+KIEF LPD + + HIF+IH   M++  D+  + L     + 
Sbjct: 306 TKQVETLDPVLIRPGRIDKKIEFHLPDEKTKKHIFQIHTSRMTLANDVTLDDLIMAKDDF 365

Query: 381 TGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYAKFSATP 427
           +GA+I+++CTEAG+ A+R  R  AT +DF +++  V+  Y K    P
Sbjct: 366 SGADIKAICTEAGLMALREHRMKATNEDFKKSIESVL--YKKHEGIP 410


>gi|239742549 PREDICTED: hypothetical protein LOC345645 [Homo
           sapiens]
          Length = 415

 Score =  252 bits (644), Expect = 4e-67
 Identities = 126/287 (43%), Positives = 192/287 (66%), Gaps = 21/287 (7%)

Query: 146 KYQIHIPLPPKID---PTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFV 202
           ++++H  +   +D   P VTMM+VE+ P  TY + GG   QI++++E +E PL HPE + 
Sbjct: 140 RHKVHAVIGVLMDDTGPLVTMMKVEKAPQETYVNTGGLDNQIQEIKESMELPLPHPEYYE 199

Query: 203 NLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFE 262
            +G +PPKGV+L GPPGT              A F+RV+GSEL+QKY+G+G ++VR++F+
Sbjct: 200 EMGTKPPKGVILCGPPGT--------------ATFLRVVGSELIQKYLGDGPKLVRQVFQ 245

Query: 263 MARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLEL--INQLDGFDPRGNIKVLMA 320
           +A      ++F DEI+AIG  R+D  +GG+ E+Q+TMLEL  +NQL GFD R ++KV+MA
Sbjct: 246 VAEEHAPSIMFTDEIEAIGTKRYDSNSGGEREIQQTMLELELLNQLGGFDSREDVKVIMA 305

Query: 321 TNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNS 380
           T + +TLDP L+RPGR+D+KIEF LPD + + HIF+IH   M++  D+  + L     + 
Sbjct: 306 TKQVETLDPVLIRPGRIDKKIEFHLPDEKTKKHIFQIHTSRMTLANDVTLDDLIMAKDDF 365

Query: 381 TGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYAKFSATP 427
           +GA+I+++CTEAG+ A+R  R  AT +DF +++  V+  Y K    P
Sbjct: 366 SGADIKAICTEAGLMALREHRMKATNEDFKKSIESVL--YKKHEGIP 410


>gi|5802970 AFG3 ATPase family gene 3-like 2 [Homo sapiens]
          Length = 797

 Score =  210 bits (535), Expect = 2e-54
 Identities = 110/265 (41%), Positives = 163/265 (61%), Gaps = 5/265 (1%)

Query: 162 TMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTG 221
           T   ++++ DV + DV GC+E   ++ E V   L +P+++ +LG + PKG +L GPPGTG
Sbjct: 295 TAKVLKDEIDVKFKDVAGCEEAKLEIMEFVNF-LKNPKQYQDLGAKIPKGAILTGPPGTG 353

Query: 222 KTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIG 281
           KTL A+A A   +  FI V GSE ++ +VG G   VR+LF +AR    C++F DEIDA+G
Sbjct: 354 KTLLAKATAGEANVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVG 413

Query: 282 GARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKI 341
             R     GG +E + T+ +L+ ++DGF+   N+ +L  TNRPD LDPAL+RPGR DR+I
Sbjct: 414 RKRGRGNFGGQSEQENTLNQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQI 473

Query: 342 EFSLPDLEGRTHIFKIHARSM----SVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAI 397
               PD++GR  IFK+H R +    ++E+D     LA L P  +GA++ +VC EA + A 
Sbjct: 474 FIGPPDIKGRASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAA 533

Query: 398 RARRKIATEKDFLEAVNKVIKSYAK 422
           R       +K F +A+ +VI    K
Sbjct: 534 RHLSDSINQKHFEQAIERVIGGLEK 558


>gi|6005942 valosin-containing protein [Homo sapiens]
          Length = 806

 Score =  208 bits (529), Expect = 9e-54
 Identities = 103/277 (37%), Positives = 164/277 (59%), Gaps = 5/277 (1%)

Query: 122 VVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCK 181
           ++DL D+    ++   + V +D  ++ +    P  +  TV      E P VT+ D+GG +
Sbjct: 429 LIDLEDETIDAEVMNSLAVTMDDFRWALSQSNPSALRETVV-----EVPQVTWEDIGGLE 483

Query: 182 EQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVI 241
           +   +L+E+V+ P+ HP++F+  G+ P KGVL +GPPG GKTL A+A+AN   A FI + 
Sbjct: 484 DVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQANFISIK 543

Query: 242 GSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLE 301
           G EL+  + GE    VRE+F+ AR    C++FFDE+D+I  AR  +   G     R + +
Sbjct: 544 GPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKARGGNIGDGGGAADRVINQ 603

Query: 302 LINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARS 361
           ++ ++DG   + N+ ++ ATNRPD +DPA++RPGRLD+ I   LPD + R  I K + R 
Sbjct: 604 ILTEMDGMSTKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRVAILKANLRK 663

Query: 362 MSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIR 398
             V +D+  E LA++    +GA++  +C  A   AIR
Sbjct: 664 SPVAKDVDLEFLAKMTNGFSGADLTEICQRACKLAIR 700



 Score =  200 bits (508), Expect = 2e-51
 Identities = 99/242 (40%), Positives = 153/242 (63%), Gaps = 3/242 (1%)

Query: 167 EEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCA 226
           E   +V Y D+GGC++Q+ +++E+VE PL HP  F  +G++PP+G+LL+GPPGTGKTL A
Sbjct: 196 ESLNEVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIA 255

Query: 227 RAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFD 286
           RAVAN T A F  + G E++ K  GE    +R+ FE A      +IF DE+DAI   R  
Sbjct: 256 RAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKR-- 313

Query: 287 DGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLP 346
           +   G+ E +R + +L+  +DG   R ++ V+ ATNRP+++DPAL R GR DR+++  +P
Sbjct: 314 EKTHGEVE-RRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIP 372

Query: 347 DLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATE 406
           D  GR  I +IH ++M +  D+  E +A       GA++ ++C+EA + AIR +  +   
Sbjct: 373 DATGRLEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAALQAIRKKMDLIDL 432

Query: 407 KD 408
           +D
Sbjct: 433 ED 434


>gi|157671927 spermatogenesis associated 5 [Homo sapiens]
          Length = 893

 Score =  203 bits (517), Expect = 2e-52
 Identities = 106/249 (42%), Positives = 152/249 (61%), Gaps = 3/249 (1%)

Query: 170 PDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAV 229
           P+V++SD+GG +    KL + VE PL HPE F+ +GI+PPKGVLL+GPPG  KT+ A+A+
Sbjct: 622 PNVSWSDIGGLESIKLKLEQAVEWPLKHPESFIRMGIQPPKGVLLYGPPGCSKTMIAKAL 681

Query: 230 ANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGA 289
           AN +   F+ + G EL+ KYVGE  R VRE F  AR     +IFFDE+DA+   R     
Sbjct: 682 ANESGLNFLAIKGPELMNKYVGESERAVRETFRKARAVAPSIIFFDELDALAVER-GSSL 740

Query: 290 GGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLE 349
           G  N   R + +L+ ++DG +   ++ +L ATNRPD +D ALMRPGR+DR I   LPD  
Sbjct: 741 GAGNVADRVLAQLLTEMDGIEQLKDVTILAATNRPDRIDKALMRPGRIDRIIYVPLPDAA 800

Query: 350 GRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIR--ARRKIATEK 407
            R  IFK+   SM V  ++  + L       +GAEI +VC EA + A+    +  +  ++
Sbjct: 801 TRREIFKLQFHSMPVSNEVDLDELILQTDAYSGAEIVAVCREAALLALEEDIQANLIMKR 860

Query: 408 DFLEAVNKV 416
            F +A++ V
Sbjct: 861 HFTQALSTV 869



 Score =  167 bits (422), Expect = 2e-41
 Identities = 101/264 (38%), Positives = 144/264 (54%), Gaps = 23/264 (8%)

Query: 172 VTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVAN 231
           VTY  +GG   Q++ +RE++E PL  PE F + GI  P+GVLL+GPPGTGKT+ ARAVAN
Sbjct: 350 VTYDMIGGLSSQLKAIREIIELPLKQPELFKSYGIPAPRGVLLYGPPGTGKTMIARAVAN 409

Query: 232 RTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGG 291
              A    + G E++ K+ GE    +R++F  A  +   +IF DE+DA+   R     G 
Sbjct: 410 EVGAYVSVINGPEIISKFYGETEAKLRQIFAEATLRHPSIIFIDELDALCPKR----EGA 465

Query: 292 DNEVQ-RTMLELINQLDGFD---PRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPD 347
            NEV+ R +  L+  +DG       G + VL ATNRP  LD AL RPGR D++IE  +P+
Sbjct: 466 QNEVEKRVVASLLTLMDGIGSEVSEGQVLVLGATNRPHALDAALRRPGRFDKEIEIGVPN 525

Query: 348 LEGRTHIF-KIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRK---- 402
            + R  I  K+  R   +  +     LA       GA+++ +C EAG+ A+R   K    
Sbjct: 526 AQDRLDILQKLLRRVPHLLTEAELLQLANSAHGYVGADLKVLCNEAGLCALRRILKKQPN 585

Query: 403 ----------IATEKDFLEAVNKV 416
                       T KDFL+A+N +
Sbjct: 586 LPDVKVAGLVKITLKDFLQAMNDI 609


>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
          Length = 1390

 Score =  183 bits (465), Expect = 2e-46
 Identities = 114/277 (41%), Positives = 157/277 (56%), Gaps = 18/277 (6%)

Query: 131 PTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREV 190
           P +  +    G+ +++ +I   L   +DP    MQ++    V +  VGG    I  L+E+
Sbjct: 389 PLNFRKDELKGIYKDRMKIGASLAD-VDP----MQLDSS--VRFDSVGGLSNHIAALKEM 441

Query: 191 VETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTD------ACFIRVIGSE 244
           V  PLL+PE F    I+PP+G L +GPPGTGKTL ARA+AN         A F+R  G++
Sbjct: 442 VVFPLLYPEVFEKFKIQPPRGCLFYGPPGTGKTLVARALANECSQGDKRVAFFMRK-GAD 500

Query: 245 LVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLELIN 304
            + K+VGE  R +R LF+ A   +  +IFFDEID +   R        + +  T+L L  
Sbjct: 501 CLSKWVGESERQLRLLFDQAYQMRPSIIFFDEIDGLAPVRSSRQDQIHSSIVSTLLAL-- 558

Query: 305 QLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSV 364
            +DG D RG I V+ ATNR D++DPAL RPGR DR+  FSLPD E R  I KIH R  + 
Sbjct: 559 -MDGLDSRGEIVVIGATNRLDSIDPALRRPGRFDREFLFSLPDKEARKEILKIHTRDWNP 617

Query: 365 E-RDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRAR 400
           +  D   E LA  C    GA+I+S+C EA + A+R R
Sbjct: 618 KPLDTFLEELAENCVGYCGADIKSICAEAALCALRRR 654


>gi|4507173 spastic paraplegia 7 isoform 1 [Homo sapiens]
          Length = 795

 Score =  182 bits (463), Expect = 4e-46
 Identities = 106/256 (41%), Positives = 150/256 (58%), Gaps = 4/256 (1%)

Query: 172 VTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVAN 231
           V++ DV G  E   ++RE V+  L  PERF+ LG + PKG LL GPPG GKTL A+AVA 
Sbjct: 306 VSFKDVAGMHEAKLEVREFVDY-LKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVAT 364

Query: 232 RTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGG 291
                F+ + G E V+   G GA  VR LF+ AR +  C+++ DEIDA+G  R    +G 
Sbjct: 365 EAQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGF 424

Query: 292 DN-EVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEG 350
            N E ++T+ +L+ ++DG     ++ VL +TNR D LD ALMRPGRLDR +   LP L+ 
Sbjct: 425 SNTEEEQTLNQLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLPTLQE 484

Query: 351 RTHIFKIHARSMSVERDIRF--ELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKD 408
           R  IF+ H +S+ + +   F  + LA L P  +GA+I ++C EA + A R         +
Sbjct: 485 RREIFEQHLKSLKLTQSSTFYSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTLN 544

Query: 409 FLEAVNKVIKSYAKFS 424
           F  AV +V+   AK S
Sbjct: 545 FEYAVERVLAGTAKKS 560


>gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens]
          Length = 1458

 Score =  181 bits (458), Expect = 1e-45
 Identities = 107/271 (39%), Positives = 153/271 (56%), Gaps = 16/271 (5%)

Query: 136 EGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPL 195
           E +  G+ R + ++   L   +DP    M +++   V +  +GG    I  L+E+V  PL
Sbjct: 368 EDLASGILRERVKVGASLAD-VDP----MNIDKS--VRFDSIGGLSHHIHALKEMVVFPL 420

Query: 196 LHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTD-----ACFIRVIGSELVQKYV 250
           L+PE F    I+PP+G L +GPPGTGKTL ARA+AN          F    G++ + K+V
Sbjct: 421 LYPEIFEKFKIQPPRGCLFYGPPGTGKTLVARALANECSQGDKKVAFFMRKGADCLSKWV 480

Query: 251 GEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFD 310
           GE  R +R LF+ A   +  +IFFDEID +   R        + +  T+L L   +DG D
Sbjct: 481 GESERQLRLLFDQAYLMRPSIIFFDEIDGLAPVRSSRQDQIHSSIVSTLLAL---MDGLD 537

Query: 311 PRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVE-RDIR 369
            RG I V+ ATNR D++DPAL RPGR DR+  F+LPD + R HI +IH R  + +  D  
Sbjct: 538 NRGEIVVIGATNRLDSIDPALRRPGRFDREFLFNLPDQKARKHILQIHTRDWNPKLSDAF 597

Query: 370 FELLARLCPNSTGAEIRSVCTEAGMFAIRAR 400
              LA  C    GA+I+++CTEA + A+R R
Sbjct: 598 LGELAEKCVGYCGADIKALCTEAALIALRRR 628


>gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]
          Length = 750

 Score =  176 bits (445), Expect = 5e-44
 Identities = 104/269 (38%), Positives = 156/269 (57%), Gaps = 19/269 (7%)

Query: 170 PDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAV 229
           P+VT++D+G  ++  E+L   +  P+ +P++F  LG+  P GVLL GPPG GKTL A+AV
Sbjct: 470 PNVTWADIGALEDIREELTMAILAPVRNPDQFKALGLVTPAGVLLAGPPGCGKTLLAKAV 529

Query: 230 ANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGA 289
           AN +   FI V G EL+  YVGE  R VR++F+ A+    C+IFFDE+DA+   R D   
Sbjct: 530 ANESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDALCPRRSDRET 589

Query: 290 GGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLE 349
           G      R + +L+ ++DG + R  + ++ ATNRPD +DPA++RPGRLD+ +   LP   
Sbjct: 590 GAS---VRVVNQLLTEMDGLEARQQVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPPPA 646

Query: 350 GRTHIFKIHARSMS---VERDIRFELLA--RLCPNSTGAEIRSVCTEAGMFAIR---ARR 401
            R  I K   ++ +   ++ D+  E +A    C   TGA++ ++  EA + A+R   AR+
Sbjct: 647 DRLAILKTITKNGTKPPLDADVNLEAIAGDLRCDCYTGADLSALVREASICALRQEMARQ 706

Query: 402 KIATE--------KDFLEAVNKVIKSYAK 422
           K   E        K F EA  KV  S +K
Sbjct: 707 KSGNEKGELKVSHKHFEEAFKKVRSSISK 735



 Score =  155 bits (391), Expect = 9e-38
 Identities = 86/227 (37%), Positives = 128/227 (56%), Gaps = 1/227 (0%)

Query: 171 DVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVA 230
           +V + DVGG    ++++ +++   + HPE + +LG+ PP+GVLL GPPG GKTL A A+A
Sbjct: 155 NVKFEDVGGNDMTLKEVCKML-IHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHAIA 213

Query: 231 NRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAG 290
              D   ++V   E+V    GE  + +RELFE A +   C+IF DEIDAI   R      
Sbjct: 214 GELDLPILKVAAPEIVSGVSGESEQKLRELFEQAVSNAPCIIFIDEIDAITPKREVASKD 273

Query: 291 GDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEG 350
            +  +   +L  ++ L+       + V+ ATNRPD+LDPAL R GR DR+I   +PD   
Sbjct: 274 MERRIVAQLLTCMDDLNNVAATARVLVIGATNRPDSLDPALRRAGRFDREICLGIPDEAS 333

Query: 351 RTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAI 397
           R  I +   R + + +   F  LA L P   GA++ ++C EA M A+
Sbjct: 334 RERILQTLCRKLRLPQAFDFCHLAHLTPGFVGADLMALCREAAMCAV 380


>gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]
          Length = 856

 Score =  176 bits (445), Expect = 5e-44
 Identities = 104/269 (38%), Positives = 156/269 (57%), Gaps = 19/269 (7%)

Query: 170 PDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAV 229
           P+VT++D+G  ++  E+L   +  P+ +P++F  LG+  P GVLL GPPG GKTL A+AV
Sbjct: 576 PNVTWADIGALEDIREELTMAILAPVRNPDQFKALGLVTPAGVLLAGPPGCGKTLLAKAV 635

Query: 230 ANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGA 289
           AN +   FI V G EL+  YVGE  R VR++F+ A+    C+IFFDE+DA+   R D   
Sbjct: 636 ANESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDALCPRRSDRET 695

Query: 290 GGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLE 349
           G      R + +L+ ++DG + R  + ++ ATNRPD +DPA++RPGRLD+ +   LP   
Sbjct: 696 GAS---VRVVNQLLTEMDGLEARQQVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPPPA 752

Query: 350 GRTHIFKIHARSMS---VERDIRFELLA--RLCPNSTGAEIRSVCTEAGMFAIR---ARR 401
            R  I K   ++ +   ++ D+  E +A    C   TGA++ ++  EA + A+R   AR+
Sbjct: 753 DRLAILKTITKNGTKPPLDADVNLEAIAGDLRCDCYTGADLSALVREASICALRQEMARQ 812

Query: 402 KIATE--------KDFLEAVNKVIKSYAK 422
           K   E        K F EA  KV  S +K
Sbjct: 813 KSGNEKGELKVSHKHFEEAFKKVRSSISK 841



 Score =  155 bits (391), Expect = 9e-38
 Identities = 86/227 (37%), Positives = 128/227 (56%), Gaps = 1/227 (0%)

Query: 171 DVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVA 230
           +V + DVGG    ++++ +++   + HPE + +LG+ PP+GVLL GPPG GKTL A A+A
Sbjct: 261 NVKFEDVGGNDMTLKEVCKML-IHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHAIA 319

Query: 231 NRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAG 290
              D   ++V   E+V    GE  + +RELFE A +   C+IF DEIDAI   R      
Sbjct: 320 GELDLPILKVAAPEIVSGVSGESEQKLRELFEQAVSNAPCIIFIDEIDAITPKREVASKD 379

Query: 291 GDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEG 350
            +  +   +L  ++ L+       + V+ ATNRPD+LDPAL R GR DR+I   +PD   
Sbjct: 380 MERRIVAQLLTCMDDLNNVAATARVLVIGATNRPDSLDPALRRAGRFDREICLGIPDEAS 439

Query: 351 RTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAI 397
           R  I +   R + + +   F  LA L P   GA++ ++C EA M A+
Sbjct: 440 RERILQTLCRKLRLPQAFDFCHLAHLTPGFVGADLMALCREAAMCAV 486


>gi|21327685 YME1-like 1 isoform 1 [Homo sapiens]
          Length = 773

 Score =  173 bits (439), Expect = 2e-43
 Identities = 96/261 (36%), Positives = 158/261 (60%), Gaps = 6/261 (2%)

Query: 157 IDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFG 216
           +D  V  +Q++   +VT+  V G +E  ++L+EVVE  L +P++F  LG + PKG+LL G
Sbjct: 324 LDSAVDPVQMK---NVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVG 379

Query: 217 PPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDE 276
           PPGTGKTL ARAVA   D  F    GSE  + +VG GA  +R LF  A+    C+IF DE
Sbjct: 380 PPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDE 439

Query: 277 IDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGR 336
           +D++GG R +      +  ++T+ +L+ ++DGF P   + ++ ATN P+ LD AL+RPGR
Sbjct: 440 LDSVGGKRIESPMHPYS--RQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGR 497

Query: 337 LDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFA 396
            D ++    PD++GRT I K +   +  ++ +  E++AR     +GAE+ ++  +A + A
Sbjct: 498 FDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKA 557

Query: 397 IRARRKIATEKDFLEAVNKVI 417
               +++ T K+   + +K++
Sbjct: 558 AVDGKEMVTMKELEFSKDKIL 578


>gi|7657689 YME1-like 1 isoform 3 [Homo sapiens]
          Length = 716

 Score =  173 bits (439), Expect = 2e-43
 Identities = 96/261 (36%), Positives = 158/261 (60%), Gaps = 6/261 (2%)

Query: 157 IDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFG 216
           +D  V  +Q++   +VT+  V G +E  ++L+EVVE  L +P++F  LG + PKG+LL G
Sbjct: 267 LDSAVDPVQMK---NVTFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVG 322

Query: 217 PPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDE 276
           PPGTGKTL ARAVA   D  F    GSE  + +VG GA  +R LF  A+    C+IF DE
Sbjct: 323 PPGTGKTLLARAVAGEADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDE 382

Query: 277 IDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGR 336
           +D++GG R +      +  ++T+ +L+ ++DGF P   + ++ ATN P+ LD AL+RPGR
Sbjct: 383 LDSVGGKRIESPMHPYS--RQTINQLLAEMDGFKPNEGVIIIGATNFPEALDNALIRPGR 440

Query: 337 LDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFA 396
            D ++    PD++GRT I K +   +  ++ +  E++AR     +GAE+ ++  +A + A
Sbjct: 441 FDMQVTVPRPDVKGRTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKA 500

Query: 397 IRARRKIATEKDFLEAVNKVI 417
               +++ T K+   + +K++
Sbjct: 501 AVDGKEMVTMKELEFSKDKIL 521


>gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens]
          Length = 753

 Score =  168 bits (425), Expect = 1e-41
 Identities = 100/285 (35%), Positives = 159/285 (55%), Gaps = 26/285 (9%)

Query: 154 PPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVL 213
           P      + +M +  KP V + ++GG ++   KL++ +E PL  P  FV +G+  PKGVL
Sbjct: 446 PSSFRSVIGLMDI--KP-VDWEEIGGLEDVKLKLKQSIEWPLKFPWEFVRMGLTQPKGVL 502

Query: 214 LFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIF 273
           L+GPPG  KT   RA+A      F+ V G++L   +VG+  +++ ++F  AR     ++F
Sbjct: 503 LYGPPGCAKTTLVRALATSCHCSFVSVSGADLFSPFVGDSEKVLSQIFRQARASTPAILF 562

Query: 274 FDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDG-----FDPRG--------------N 314
            DEID+I GAR     G D + +R +  L+N+LDG      + RG              +
Sbjct: 563 LDEIDSILGARSASKTGCDVQ-ERVLSVLLNELDGVGLKTIERRGSKSSQQEFQEVFNRS 621

Query: 315 IKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLA 374
           + ++ ATNRPD LD AL+RPGRLD+ I    PD +GR  I K+  ++M +  D+  E LA
Sbjct: 622 VMIIAATNRPDVLDTALLRPGRLDKIIYIPPPDHKGRLSILKVCTKTMPIGPDVSLENLA 681

Query: 375 RLCPNSTGAEIRSVCTEAGMFAIRARRKIAT---EKDFLEAVNKV 416
                 +GA++R++CTEA + A++     AT   ++ FL+++  V
Sbjct: 682 AETCFFSGADLRNLCTEAALLALQENGLDATTVKQEHFLKSLKTV 726



 Score =  145 bits (367), Expect = 5e-35
 Identities = 91/260 (35%), Positives = 131/260 (50%), Gaps = 16/260 (6%)

Query: 165 QVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTL 224
           + + +P+V    +GG  E  + LRE++  PL +P     LG+  P+GVLL GPPG GKT 
Sbjct: 193 EAQPQPEVP---LGGLSEAADSLRELLRLPLRYPRALTALGLAVPRGVLLAGPPGVGKTQ 249

Query: 225 CARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMAR---TKKACLIFFDEIDAIG 281
             RAVA    A  + V    L     GE    VR +F+ AR   ++   L+F DE+DA+ 
Sbjct: 250 LVRAVAREAGAELLAVSAPALQGSRPGETEENVRRVFQRARELASRGPSLLFLDEMDALC 309

Query: 282 GARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKI 341
             R     G      R + +++  LDG      + V+ ATNRPD LDPAL RPGR DR++
Sbjct: 310 PQR-----GSRAPESRVVAQVLTLLDGASGDREVVVVGATNRPDALDPALRRPGRFDREV 364

Query: 342 EFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARR 401
               P L+ R  I ++    M +   +   LLA +     GA++ ++C EA M A+    
Sbjct: 365 VIGTPTLKQRKEILQVITSKMPISSHVDLGLLAEMTVGYVGADLTALCREAAMHALLHSE 424

Query: 402 K-----IATEKDFLEAVNKV 416
           K     +  E DFLEA   +
Sbjct: 425 KNQDNPVIDEIDFLEAFKNI 444


>gi|4505725 peroxin1 [Homo sapiens]
          Length = 1283

 Score =  159 bits (403), Expect = 4e-39
 Identities = 84/227 (37%), Positives = 132/227 (58%), Gaps = 3/227 (1%)

Query: 171  DVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVA 230
            D+ +  +GG  E  + L + ++ P  +PE F NL I    G+LL+GPPGTGKTL A  +A
Sbjct: 836  DLGWDKIGGLHEVRQILMDTIQLPAKYPELFANLPIRQRTGILLYGPPGTGKTLLAGVIA 895

Query: 231  NRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAG 290
              +   FI V G EL+ KY+G   + VR++F  A+  K C++FFDE ++I   R  D  G
Sbjct: 896  RESRMNFISVKGPELLSKYIGASEQAVRDIFIRAQAAKPCILFFDEFESIAPRRGHDNTG 955

Query: 291  GDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEG 350
                  R + +L+ QLDG +    + VL AT+RPD +DPAL+RPGRLD+ +    PD   
Sbjct: 956  ---VTDRVVNQLLTQLDGVEGLQGVYVLAATSRPDLIDPALLRPGRLDKCVYCPPPDQVS 1012

Query: 351  RTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAI 397
            R  I  + + S+ +  D+  + +A +  + TGA+++++   A + A+
Sbjct: 1013 RLEILNVLSDSLPLADDVDLQHVASVTDSFTGADLKALLYNAQLEAL 1059


>gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]
          Length = 980

 Score =  159 bits (402), Expect = 5e-39
 Identities = 90/233 (38%), Positives = 135/233 (57%), Gaps = 5/233 (2%)

Query: 170 PDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAV 229
           P V++ DVGG +E  +++ E ++ PL HPE  ++LG+    G+LL GPPGTGKTL A+AV
Sbjct: 700 PSVSWHDVGGLQEVKKEILETIQLPLEHPE-LLSLGLRR-SGLLLHGPPGTGKTLLAKAV 757

Query: 230 ANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGA 289
           A      F+ V G EL+  YVG+    VRE+F  AR    C+IFFDE+D++  +R   G 
Sbjct: 758 ATECSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRSGD 817

Query: 290 GGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSL-PDL 348
            G   + R + +L+ +LDG     ++ V+ ATNRPD LDPAL+RPGR D+ +      D 
Sbjct: 818 SG-GVMDRVVSQLLAELDGLHSTQDVFVIGATNRPDLLDPALLRPGRFDKLVFVGANEDR 876

Query: 349 EGRTHIFKIHARSMSVERDIRFELLARLC-PNSTGAEIRSVCTEAGMFAIRAR 400
             +  +     R   +E  +    +   C P  TGA++ S+C++A   A++ R
Sbjct: 877 ASQLRVLSAITRKFKLEPSVSLVNVLDCCPPQLTGADLYSLCSDAMTAALKRR 929



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 43/185 (23%), Positives = 76/185 (41%), Gaps = 4/185 (2%)

Query: 212 VLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACL 271
           VLL GPPG GKT    A  +      ++V  S L  +  G     ++ +F  AR  +  +
Sbjct: 466 VLLRGPPGCGKTTVVAAACSHLGLHLLKVPCSSLCAESSGAVETKLQAIFSRARRCRPAV 525

Query: 272 IFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPAL 331
           +    +D +G  R  DG G D  V   +  L+   D  +    + V+  T+R   L PA 
Sbjct: 526 LLLTAVDLLGRDR--DGLGEDARVMAVLRHLLLNEDPLNSCPPLMVVATTSRAQDL-PAD 582

Query: 332 MRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTE 391
           ++      ++E        R  I +     + + +++    LAR C      ++ ++ T 
Sbjct: 583 VQTA-FPHELEVPALSEGQRLSILRALTAHLPLGQEVNLAQLARRCAGFVVGDLYALLTH 641

Query: 392 AGMFA 396
           +   A
Sbjct: 642 SSRAA 646


>gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens]
          Length = 490

 Score =  151 bits (381), Expect = 1e-36
 Identities = 95/243 (39%), Positives = 133/243 (54%), Gaps = 14/243 (5%)

Query: 166 VEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLC 225
           V   P + + D+   +E  + LRE V  P+  P+ F  +   P KGVL+ GPPGTGKT+ 
Sbjct: 199 VSRNPSIHWDDIADLEEAKKLLREAVVLPMWMPDFFKGIR-RPWKGVLMVGPPGTGKTML 257

Query: 226 ARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARF 285
           A+AVA      F  V  S L  KY GE  ++VR LFEMAR      IF DEID+I   R 
Sbjct: 258 AKAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRR- 316

Query: 286 DDGAGGDNEV-QRTMLELINQLDGF-------DPRGNIKVLMATNRPDTLDPALMRPGRL 337
             G   ++E  +R   EL+ Q+DG        DP   + VL ATN P  +D AL R  RL
Sbjct: 317 --GTSDEHEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDEALRR--RL 372

Query: 338 DRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAI 397
           +++I   LP  +GR  + KI+ R + ++ DI+ E +A      +GA+I +VC +A + A+
Sbjct: 373 EKRIYIPLPTAKGRAELLKINLREVELDPDIQLEDIAEKIEGYSGADITNVCRDASLMAM 432

Query: 398 RAR 400
           R R
Sbjct: 433 RRR 435


>gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens]
          Length = 490

 Score =  151 bits (381), Expect = 1e-36
 Identities = 95/243 (39%), Positives = 133/243 (54%), Gaps = 14/243 (5%)

Query: 166 VEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLC 225
           V   P + + D+   +E  + LRE V  P+  P+ F  +   P KGVL+ GPPGTGKT+ 
Sbjct: 199 VSRNPSIHWDDIADLEEAKKLLREAVVLPMWMPDFFKGIR-RPWKGVLMVGPPGTGKTML 257

Query: 226 ARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARF 285
           A+AVA      F  V  S L  KY GE  ++VR LFEMAR      IF DEID+I   R 
Sbjct: 258 AKAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRR- 316

Query: 286 DDGAGGDNEV-QRTMLELINQLDGF-------DPRGNIKVLMATNRPDTLDPALMRPGRL 337
             G   ++E  +R   EL+ Q+DG        DP   + VL ATN P  +D AL R  RL
Sbjct: 317 --GTSDEHEASRRVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDEALRR--RL 372

Query: 338 DRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAI 397
           +++I   LP  +GR  + KI+ R + ++ DI+ E +A      +GA+I +VC +A + A+
Sbjct: 373 EKRIYIPLPTAKGRAELLKINLREVELDPDIQLEDIAEKIEGYSGADITNVCRDASLMAM 432

Query: 398 RAR 400
           R R
Sbjct: 433 RRR 435


>gi|5901990 katanin p60 subunit A 1 [Homo sapiens]
          Length = 491

 Score =  147 bits (372), Expect = 1e-35
 Identities = 102/279 (36%), Positives = 143/279 (51%), Gaps = 31/279 (11%)

Query: 166 VEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLC 225
           + + P+V + D+    E  + L+E V  P+  PE F  +   P KGVL+ GPPGTGKTL 
Sbjct: 200 ISQNPNVRWDDIADLVEAKKLLKEAVVLPMWMPEFFKGIR-RPWKGVLMVGPPGTGKTLL 258

Query: 226 ARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARF 285
           A+AVA      F  V  S L  KY GE  ++VR LFEMAR      IF DEID+I   R 
Sbjct: 259 AKAVATECKTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYSPATIFIDEIDSICSRR- 317

Query: 286 DDGAGGDNEV-QRTMLELINQLDGF-------DPRGNIKVLMATNRPDTLDPALMRPGRL 337
             G   ++E  +R   EL+ Q+DG        DP   + VL ATN P  +D AL R  RL
Sbjct: 318 --GTSEEHEASRRVKAELLVQMDGVGGTSENDDPSKMVMVLAATNFPWDIDEALRR--RL 373

Query: 338 DRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAI 397
           +++I   LP  +GR  + +I  R + +  D+    +A      +GA+I +VC +A + A+
Sbjct: 374 EKRIYIPLPSAKGREELLRISLRELELADDVDLASIAENMEGYSGADITNVCRDASLMAM 433

Query: 398 RAR---------RKIATE--------KDFLEAVNKVIKS 419
           R R         R ++ E        +DF  A+ KV KS
Sbjct: 434 RRRIEGLTPEEIRNLSKEEMHMPTTMEDFEMALKKVSKS 472


>gi|31742536 fidgetin-like 1 [Homo sapiens]
          Length = 674

 Score =  139 bits (351), Expect = 4e-33
 Identities = 85/250 (34%), Positives = 134/250 (53%), Gaps = 9/250 (3%)

Query: 153 LPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGV 212
           L PK+   +    ++  P V + D+ G +     ++E+V  P+L P+ F  L   PPKG+
Sbjct: 379 LEPKMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLR-GPPKGI 437

Query: 213 LLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLI 272
           LLFGPPGTGKTL  + +A+++ A F  +  S L  K+VGEG +MVR LF +AR ++  +I
Sbjct: 438 LLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVI 497

Query: 273 FFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLM--ATNRPDTLDPA 330
           F DEID++   R   G G     +R   E + QLDG       ++L+  ATNRP  +D A
Sbjct: 498 FIDEIDSLLSQR---GDGEHESSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEA 554

Query: 331 LMRPGRLDRKIEFSLPDLEGRTHI-FKIHARSMSVERDIRFELLARLCPNSTGAEIRSVC 389
             R  RL +++   LP+   R  I   + ++      +   E + +     +GA++  +C
Sbjct: 555 ARR--RLVKRLYIPLPEASARKQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLC 612

Query: 390 TEAGMFAIRA 399
            EA +  IR+
Sbjct: 613 REASLGPIRS 622


>gi|112789543 fidgetin-like 1 [Homo sapiens]
          Length = 674

 Score =  139 bits (351), Expect = 4e-33
 Identities = 85/250 (34%), Positives = 134/250 (53%), Gaps = 9/250 (3%)

Query: 153 LPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGV 212
           L PK+   +    ++  P V + D+ G +     ++E+V  P+L P+ F  L   PPKG+
Sbjct: 379 LEPKMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWPMLRPDIFTGLR-GPPKGI 437

Query: 213 LLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLI 272
           LLFGPPGTGKTL  + +A+++ A F  +  S L  K+VGEG +MVR LF +AR ++  +I
Sbjct: 438 LLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSKWVGEGEKMVRALFAVARCQQPAVI 497

Query: 273 FFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLM--ATNRPDTLDPA 330
           F DEID++   R   G G     +R   E + QLDG       ++L+  ATNRP  +D A
Sbjct: 498 FIDEIDSLLSQR---GDGEHESSRRIKTEFLVQLDGATTSSEDRILVVGATNRPQEIDEA 554

Query: 331 LMRPGRLDRKIEFSLPDLEGRTHI-FKIHARSMSVERDIRFELLARLCPNSTGAEIRSVC 389
             R  RL +++   LP+   R  I   + ++      +   E + +     +GA++  +C
Sbjct: 555 ARR--RLVKRLYIPLPEASARKQIVINLMSKEQCCLSEEEIEQIVQQSDAFSGADMTQLC 612

Query: 390 TEAGMFAIRA 399
            EA +  IR+
Sbjct: 613 REASLGPIRS 622


>gi|17865802 vacuolar protein sorting factor 4B [Homo sapiens]
          Length = 444

 Score =  131 bits (329), Expect = 1e-30
 Identities = 98/306 (32%), Positives = 160/306 (52%), Gaps = 14/306 (4%)

Query: 96  ARCTKIINADSEDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPP 155
           A+CT+ ++   +  +Y+ N ++ A+  V    Q +P D E+G        + +   P   
Sbjct: 60  AKCTEYLDRAEKLKEYLKNKEKKAQKPVK-EGQPSPAD-EKG---NDSDGEGESDDPEKK 114

Query: 156 KIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLF 215
           K+   +    V E+P+V +SDV G +   E L+E V  P+  P  F      P +G+LLF
Sbjct: 115 KLQNQLQGAIVIERPNVKWSDVAGLEGAKEALKEAVILPIKFPHLFTGKRT-PWRGILLF 173

Query: 216 GPPGTGKTLCARAVANRTD-ACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFF 274
           GPPGTGK+  A+AVA   + + F  +  S+LV K++GE  ++V+ LF++AR  K  +IF 
Sbjct: 174 GPPGTGKSYLAKAVATEANNSTFFSISSSDLVSKWLGESEKLVKNLFQLARENKPSIIFI 233

Query: 275 DEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFD-PRGNIKVLMATNRPDTLDPALMR 333
           DEID++ G+R ++ +      +R   E + Q+ G       I VL ATN P  LD A+ R
Sbjct: 234 DEIDSLCGSRSENES---EAARRIKTEFLVQMQGVGVDNDGILVLGATNIPWVLDSAIRR 290

Query: 334 PGRLDRKIEFSLPDLEGRTHIFKIH-ARSMSVERDIRFELLARLCPNSTGAEIRSVCTEA 392
             R +++I   LP+   R  +FK+H   + +   +  F  L R     +GA+I  +  +A
Sbjct: 291 --RFEKRIYIPLPEPHARAAMFKLHLGTTQNSLTEADFRELGRKTDGYSGADISIIVRDA 348

Query: 393 GMFAIR 398
            M  +R
Sbjct: 349 LMQPVR 354


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.137    0.395 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,494,907
Number of Sequences: 37866
Number of extensions: 749626
Number of successful extensions: 2067
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 1923
Number of HSP's gapped (non-prelim): 91
length of query: 433
length of database: 18,247,518
effective HSP length: 105
effective length of query: 328
effective length of database: 14,271,588
effective search space: 4681080864
effective search space used: 4681080864
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.