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Search of human proteins with 4502175
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4502175 apical protein of Xenopus-like [Homo sapiens]
(1616 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4502175 apical protein of Xenopus-like [Homo sapiens] 3285 0.0
gi|203098098 shroom family member 3 protein [Homo sapiens] 415 e-115
gi|118600967 shroom family member 4 [Homo sapiens] 250 9e-66
gi|31442420 shroom family member 1 [Homo sapiens] 117 7e-26
gi|38201621 eukaryotic translation initiation factor 4 gamma, 1 ... 63 3e-09
gi|38201623 eukaryotic translation initiation factor 4 gamma, 1 ... 63 3e-09
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 61 8e-09
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 60 2e-08
gi|193083191 synaptopodin 2 isoform c [Homo sapiens] 60 2e-08
gi|193083185 synaptopodin 2 isoform b [Homo sapiens] 60 2e-08
gi|193083183 synaptopodin 2 isoform a [Homo sapiens] 60 2e-08
gi|13994151 PDZ and LIM domain 1 [Homo sapiens] 57 2e-07
gi|166235178 PDZ and LIM domain protein 3 isoform b [Homo sapiens] 56 2e-07
gi|166235176 PDZ and LIM domain protein 3 isoform a [Homo sapiens] 56 2e-07
gi|166706868 synaptopodin 2-like isoform a [Homo sapiens] 55 7e-07
gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 54 9e-07
gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens] 54 1e-06
gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens] 54 1e-06
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens] 54 1e-06
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens] 54 1e-06
gi|145199237 transcription elongation factor B polypeptide 3 bin... 54 1e-06
gi|196162711 PDZ and LIM domain 4 isoform 2 [Homo sapiens] 54 2e-06
gi|19923181 PDZ and LIM domain 4 isoform 1 [Homo sapiens] 54 2e-06
gi|4507137 acidic alpha 1 syntrophin [Homo sapiens] 53 3e-06
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 52 4e-06
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 52 5e-06
gi|38327612 PDZ and LIM domain 2 isoform 3 [Homo sapiens] 52 5e-06
gi|28866957 PDZ and LIM domain 2 isoform 1 [Homo sapiens] 52 5e-06
gi|21361888 PDZ and LIM domain 2 isoform 2 [Homo sapiens] 52 5e-06
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 52 6e-06
>gi|4502175 apical protein of Xenopus-like [Homo sapiens]
Length = 1616
Score = 3285 bits (8517), Expect = 0.0
Identities = 1616/1616 (100%), Positives = 1616/1616 (100%)
Query: 1 MEGAEPRARPERLAEAETRAADGGRLVEVQLSGGAPWGFTLKGGREHGEPLVITKIEEGS 60
MEGAEPRARPERLAEAETRAADGGRLVEVQLSGGAPWGFTLKGGREHGEPLVITKIEEGS
Sbjct: 1 MEGAEPRARPERLAEAETRAADGGRLVEVQLSGGAPWGFTLKGGREHGEPLVITKIEEGS 60
Query: 61 KAAAVDKLLAGDEIVGINDIGLSGFRQEAICLVKGSHKTLKLVVKRRSELGWRPHSWHAT 120
KAAAVDKLLAGDEIVGINDIGLSGFRQEAICLVKGSHKTLKLVVKRRSELGWRPHSWHAT
Sbjct: 61 KAAAVDKLLAGDEIVGINDIGLSGFRQEAICLVKGSHKTLKLVVKRRSELGWRPHSWHAT 120
Query: 121 KFSDSHPELAASPFTSTSGCPSWSGRHHASSSSHDLSSSWEQTNLQRTLDHFSSLGSVDS 180
KFSDSHPELAASPFTSTSGCPSWSGRHHASSSSHDLSSSWEQTNLQRTLDHFSSLGSVDS
Sbjct: 121 KFSDSHPELAASPFTSTSGCPSWSGRHHASSSSHDLSSSWEQTNLQRTLDHFSSLGSVDS 180
Query: 181 LDHPSSRLSVAKSNSSIDHLGSHSKRDSAYGSFSTSSSTPDHTLSKADTSSAENILYTVG 240
LDHPSSRLSVAKSNSSIDHLGSHSKRDSAYGSFSTSSSTPDHTLSKADTSSAENILYTVG
Sbjct: 181 LDHPSSRLSVAKSNSSIDHLGSHSKRDSAYGSFSTSSSTPDHTLSKADTSSAENILYTVG 240
Query: 241 LWEAPRQGGRQAQAAGDPQGSEEKLSCFPPRVPGDSGKGPRPEYNAEPKLAAPGRSNFGP 300
LWEAPRQGGRQAQAAGDPQGSEEKLSCFPPRVPGDSGKGPRPEYNAEPKLAAPGRSNFGP
Sbjct: 241 LWEAPRQGGRQAQAAGDPQGSEEKLSCFPPRVPGDSGKGPRPEYNAEPKLAAPGRSNFGP 300
Query: 301 VWYVPDKKKAPSSPPPPPPPLRSDSFAATKSHEKAQGPVFSEAAAAQHFTALAQAQPRGD 360
VWYVPDKKKAPSSPPPPPPPLRSDSFAATKSHEKAQGPVFSEAAAAQHFTALAQAQPRGD
Sbjct: 301 VWYVPDKKKAPSSPPPPPPPLRSDSFAATKSHEKAQGPVFSEAAAAQHFTALAQAQPRGD 360
Query: 361 RRPELTDRPWRSAHPGSLGKGSGGPGCPQEAHADGSWPPSKDGASSRLQASLSSSDVRFP 420
RRPELTDRPWRSAHPGSLGKGSGGPGCPQEAHADGSWPPSKDGASSRLQASLSSSDVRFP
Sbjct: 361 RRPELTDRPWRSAHPGSLGKGSGGPGCPQEAHADGSWPPSKDGASSRLQASLSSSDVRFP 420
Query: 421 QSPHSGRHPPLYSDHSPLCADSLGQEPGAASFQNDSPPQVRGLSSCDQKLGSGWQGPRPC 480
QSPHSGRHPPLYSDHSPLCADSLGQEPGAASFQNDSPPQVRGLSSCDQKLGSGWQGPRPC
Sbjct: 421 QSPHSGRHPPLYSDHSPLCADSLGQEPGAASFQNDSPPQVRGLSSCDQKLGSGWQGPRPC 480
Query: 481 VQGDLQAAQLWAGCWPSDTALGALESLPPPTVGQSPRHHLPQPEGPPDARETGRCYPLDK 540
VQGDLQAAQLWAGCWPSDTALGALESLPPPTVGQSPRHHLPQPEGPPDARETGRCYPLDK
Sbjct: 481 VQGDLQAAQLWAGCWPSDTALGALESLPPPTVGQSPRHHLPQPEGPPDARETGRCYPLDK 540
Query: 541 GAEGCSAGAQEPPRASRAEKASQRLAASITWADGESSRICPQETPLLHSLTQEGKRRPES 600
GAEGCSAGAQEPPRASRAEKASQRLAASITWADGESSRICPQETPLLHSLTQEGKRRPES
Sbjct: 541 GAEGCSAGAQEPPRASRAEKASQRLAASITWADGESSRICPQETPLLHSLTQEGKRRPES 600
Query: 601 SPEDSATRPPPFDAHVGKPTRRSDRFATTLRNEIQMHRAKLQKSRSTVALTAAGEAEDGT 660
SPEDSATRPPPFDAHVGKPTRRSDRFATTLRNEIQMHRAKLQKSRSTVALTAAGEAEDGT
Sbjct: 601 SPEDSATRPPPFDAHVGKPTRRSDRFATTLRNEIQMHRAKLQKSRSTVALTAAGEAEDGT 660
Query: 661 GRWRAGLGGGTQEGPLAGTYKDHLKEAQARVLRATSFKRRDLDPNPGDLYPESLEHRMGD 720
GRWRAGLGGGTQEGPLAGTYKDHLKEAQARVLRATSFKRRDLDPNPGDLYPESLEHRMGD
Sbjct: 661 GRWRAGLGGGTQEGPLAGTYKDHLKEAQARVLRATSFKRRDLDPNPGDLYPESLEHRMGD 720
Query: 721 PDTVPHFWEAGLAQPPSSTSGGPHPPRIGGRRRFTAEQKLKSYSEPEKMNEVGLTRGYSP 780
PDTVPHFWEAGLAQPPSSTSGGPHPPRIGGRRRFTAEQKLKSYSEPEKMNEVGLTRGYSP
Sbjct: 721 PDTVPHFWEAGLAQPPSSTSGGPHPPRIGGRRRFTAEQKLKSYSEPEKMNEVGLTRGYSP 780
Query: 781 HQHPRTSEDTVGTFADRWKFFEETSKPVPQRPAQKQALHGIPRDKPERPRTAGRTCEGTE 840
HQHPRTSEDTVGTFADRWKFFEETSKPVPQRPAQKQALHGIPRDKPERPRTAGRTCEGTE
Sbjct: 781 HQHPRTSEDTVGTFADRWKFFEETSKPVPQRPAQKQALHGIPRDKPERPRTAGRTCEGTE 840
Query: 841 PWSRTTSLGDSLNAHSAAEKAGTSDLPRRLGTFAEYQASWKEQRKPLEARSSGRCHSADD 900
PWSRTTSLGDSLNAHSAAEKAGTSDLPRRLGTFAEYQASWKEQRKPLEARSSGRCHSADD
Sbjct: 841 PWSRTTSLGDSLNAHSAAEKAGTSDLPRRLGTFAEYQASWKEQRKPLEARSSGRCHSADD 900
Query: 901 ILDVSLDPQERPQHVHGRSRSSPSTDHYKQEASVELRRQAGDPGEPREELPSAVRAEEGQ 960
ILDVSLDPQERPQHVHGRSRSSPSTDHYKQEASVELRRQAGDPGEPREELPSAVRAEEGQ
Sbjct: 901 ILDVSLDPQERPQHVHGRSRSSPSTDHYKQEASVELRRQAGDPGEPREELPSAVRAEEGQ 960
Query: 961 STPRQADAQCREGSPGSQQHPPSQKAPNPPTFSELSHCRGAPELPREGRGRAGTLPRDYR 1020
STPRQADAQCREGSPGSQQHPPSQKAPNPPTFSELSHCRGAPELPREGRGRAGTLPRDYR
Sbjct: 961 STPRQADAQCREGSPGSQQHPPSQKAPNPPTFSELSHCRGAPELPREGRGRAGTLPRDYR 1020
Query: 1021 YSEESTPADLGPRAQSPGSPLHARGQDSWPVSSALLSKRPAPQRPPPPKREPRRYRATDG 1080
YSEESTPADLGPRAQSPGSPLHARGQDSWPVSSALLSKRPAPQRPPPPKREPRRYRATDG
Sbjct: 1021 YSEESTPADLGPRAQSPGSPLHARGQDSWPVSSALLSKRPAPQRPPPPKREPRRYRATDG 1080
Query: 1081 APADAPVGVLGRPFPTPSPASLDVYVARLSLSHSPSVFSSAQPQDTPKATVCERGSQHVS 1140
APADAPVGVLGRPFPTPSPASLDVYVARLSLSHSPSVFSSAQPQDTPKATVCERGSQHVS
Sbjct: 1081 APADAPVGVLGRPFPTPSPASLDVYVARLSLSHSPSVFSSAQPQDTPKATVCERGSQHVS 1140
Query: 1141 GDASRPLPEALLPPKQQHLRLQTATMETSRSPSPQFAPQKLTDKPPLLIQDEDSTRIERV 1200
GDASRPLPEALLPPKQQHLRLQTATMETSRSPSPQFAPQKLTDKPPLLIQDEDSTRIERV
Sbjct: 1141 GDASRPLPEALLPPKQQHLRLQTATMETSRSPSPQFAPQKLTDKPPLLIQDEDSTRIERV 1200
Query: 1201 MDNNTTVKMVPIKIVHSESQPEKESRQSLACPAEPPALPHGLEKDQIKTLSTSEQFYSRF 1260
MDNNTTVKMVPIKIVHSESQPEKESRQSLACPAEPPALPHGLEKDQIKTLSTSEQFYSRF
Sbjct: 1201 MDNNTTVKMVPIKIVHSESQPEKESRQSLACPAEPPALPHGLEKDQIKTLSTSEQFYSRF 1260
Query: 1261 CLYTRQGAEPEAPHRAQPAEPQPLGTQVPPEKDRCTSPPGLSYMKAKEKTVEDLKSEELA 1320
CLYTRQGAEPEAPHRAQPAEPQPLGTQVPPEKDRCTSPPGLSYMKAKEKTVEDLKSEELA
Sbjct: 1261 CLYTRQGAEPEAPHRAQPAEPQPLGTQVPPEKDRCTSPPGLSYMKAKEKTVEDLKSEELA 1320
Query: 1321 REIVGKDKSLADILDPSVKIKTTMDLMEGIFPKDEHLLEEAQQRRKLLPKIPSPRSTEER 1380
REIVGKDKSLADILDPSVKIKTTMDLMEGIFPKDEHLLEEAQQRRKLLPKIPSPRSTEER
Sbjct: 1321 REIVGKDKSLADILDPSVKIKTTMDLMEGIFPKDEHLLEEAQQRRKLLPKIPSPRSTEER 1380
Query: 1381 KEEPSVPAAVSLATNSTYYSTSAPKAELLIKMKDLQEQQEHEEDSGSDLDHDLSVKKQEL 1440
KEEPSVPAAVSLATNSTYYSTSAPKAELLIKMKDLQEQQEHEEDSGSDLDHDLSVKKQEL
Sbjct: 1381 KEEPSVPAAVSLATNSTYYSTSAPKAELLIKMKDLQEQQEHEEDSGSDLDHDLSVKKQEL 1440
Query: 1441 IESISRKLQVLREARESLLEDVQANTVLGAEVEAIVKGVCKPSEFDKFRMFIGDLDKVVN 1500
IESISRKLQVLREARESLLEDVQANTVLGAEVEAIVKGVCKPSEFDKFRMFIGDLDKVVN
Sbjct: 1441 IESISRKLQVLREARESLLEDVQANTVLGAEVEAIVKGVCKPSEFDKFRMFIGDLDKVVN 1500
Query: 1501 LLLSLSGRLARVENALNNLDDGASPGDRQSLLEKQRVLIQQHEDAKELKENLDRRERIVF 1560
LLLSLSGRLARVENALNNLDDGASPGDRQSLLEKQRVLIQQHEDAKELKENLDRRERIVF
Sbjct: 1501 LLLSLSGRLARVENALNNLDDGASPGDRQSLLEKQRVLIQQHEDAKELKENLDRRERIVF 1560
Query: 1561 DILANYLSEESLADYEHFVKMKSALIIEQRELEDKIHLGEEQLKCLLDSLQPERGK 1616
DILANYLSEESLADYEHFVKMKSALIIEQRELEDKIHLGEEQLKCLLDSLQPERGK
Sbjct: 1561 DILANYLSEESLADYEHFVKMKSALIIEQRELEDKIHLGEEQLKCLLDSLQPERGK 1616
>gi|203098098 shroom family member 3 protein [Homo sapiens]
Length = 1996
Score = 415 bits (1067), Expect = e-115
Identities = 379/1143 (33%), Positives = 517/1143 (45%), Gaps = 240/1143 (20%)
Query: 639 AKLQKSRSTVALTAAGEAEDGTGRWRAGLGGGTQ---EGPLAGTYKDHLKEAQARVLRAT 695
A+L +S+ST L++ E E WR G + P + Y++ +K+AQ+RVL AT
Sbjct: 883 ARLLRSQSTFQLSSEPEREP---EWRDRPGSPESPLLDAPFSRAYRNSIKDAQSRVLGAT 939
Query: 696 SFKRRDLDPNPGDLYPESLEHRMGDPDTVPHFWEAGLAQPPSSTSGGPHPPRI------- 748
SF+RRDL+ + R P P GL P +S S PH PR
Sbjct: 940 SFRRRDLELGA------PVASRSWRPR--PSSAHVGLRSPEASASASPHTPRERHSVTPA 991
Query: 749 --------------GGRRRFTAEQKLKSYSEPEKMNEVGLTRGYSP------HQHPRTSE 788
G RRR T EQK +SYSEPEKMNEVG+ P R E
Sbjct: 992 EGDLARPVPPAARRGARRRLTPEQKKRSYSEPEKMNEVGIVEEAEPAPLGPQRNGMRFPE 1051
Query: 789 DTVGTFADRWKFFEETSKPVPQ--------RPAQKQALHGIPRDKPERPRTAGRTCEGTE 840
+V ADR + FE K + Q+ AL + K + T+ C E
Sbjct: 1052 SSV---ADRRRLFERDGKACSTLSLSGPELKQFQQSALADYIQRKTGKRPTSAAGCSLQE 1108
Query: 841 PW-----SRTTSLGDSLNAHSAAEKAGTSDL---------PRRLGTF-----AEYQASWK 881
P +++ L A + A S L PRR T AE Q + +
Sbjct: 1109 PGPLRERAQSAYLQPGPAALEGSGLASASSLSSLREPSLQPRREATLLPATVAETQQAPR 1168
Query: 882 EQRK---------------------------------PLEARS----SGRCHSADDILDV 904
++ P E S +G+ SA+D+L+
Sbjct: 1169 DRSSSFAGGRRLGERRRGDLLSGANGGTRGTQRGDETPREPSSWGARAGKSMSAEDLLER 1228
Query: 905 SLDPQERPQHVHGRSRSSPSTDHYKQEASVELRRQAG-----DP----GEPREELPSAVR 955
S D P HV RSRSSP+T +Q+ V L + +G DP G L + R
Sbjct: 1229 S-DVLAGPVHV--RSRSSPATADKRQD--VLLGQDSGFGLVKDPCYLAGPGSRSLSCSER 1283
Query: 956 AEEGQS------TPRQADAQCRE-----------GSPGSQQHPPSQKAPNPP---TFSEL 995
+E TPR + C+ G+ Q+ P PP T +
Sbjct: 1284 GQEEMLPLFHHLTPRWGGSGCKAIGDSSVPSECPGTLDHQRQASRTPCPRPPLAGTQGLV 1343
Query: 996 SHCRGAPELPREGRGRAGTLPRDYRYSEEST---------PADL------------GPRA 1034
+ R AP P G +P Y + T PA + GPR
Sbjct: 1344 TDTRAAPLTPI-GTPLPSAIPSGYCSQDGQTGRQPLPPYTPAMMHRSNGHTLTQPPGPRG 1402
Query: 1035 QSPGSPLHARGQDSWPVSSALLSKRPAPQRPPPPKREPRRYRATDGAPADAPVGVLGRPF 1094
P H V + PQ PPP + + D P ++
Sbjct: 1403 CEGDGPEHG-------VEEGTRKRVSLPQWPPPSRAKWAHAAREDSLPEESSA------- 1448
Query: 1095 PTPSPASLDVYVARLSLSHSPSVFSSAQPQDTPKATVCERGSQHVSGDASRPLPEALL-- 1152
P A+L Y + SL PS+ S++ P DTP G+ G S + E++L
Sbjct: 1449 --PDFANLKHYQKQQSL---PSLCSTSDP-DTPL------GAPSTPGRISLRISESVLRD 1496
Query: 1153 -PPKQQHLRLQT--------ATMETSRSPSPQFAPQKLTDKPPLLIQDE-----DSTRIE 1198
PP + + AT + P P P + + P+ D+ T E
Sbjct: 1497 SPPPHEDYEDEVFVRDPHPKATSSPTFEPLPPPPPPPPSQETPVYSMDDFPPPPPHTVCE 1556
Query: 1199 RVMDN----------NTTVKMVPIKIVHSESQPEKESRQSLACPAEPPALPHGLEKDQIK 1248
+D+ N K+ + H Q+LA + E
Sbjct: 1557 AQLDSEDPEGPRPSFNKLSKVTIARERHMPGAAHVVGSQTLASRLQTSIKGSEAESTPPS 1616
Query: 1249 TLSTSEQFYSRFCLYTRQGAEPEAPHRAQPAEPQPLGTQVPPEKDRCTSPPGLSYMKAKE 1308
+S Q G +P AP + Q P+ EK P +
Sbjct: 1617 FMSVHAQLAGSL------GGQP-APIQTQSLSHDPVSGTQGLEKKVSPDP---------Q 1660
Query: 1309 KTVEDLKSEELAREIVGKDKSLADILDPSVKIKTTMDLMEGIFPKDEHLLEEAQQRRKLL 1368
K+ ED+++E LA+EIV +DKSLADILDP ++KTTMDLMEG+FP+D +LL+E +RK +
Sbjct: 1661 KSSEDIRTEALAKEIVHQDKSLADILDPDSRLKTTMDLMEGLFPRDVNLLKENSVKRKAI 1720
Query: 1369 PKIPSPRSTEERKEEPSVPAAVSLATNS-TYYSTSAPKAELLIKMKDLQEQQEHEEDSGS 1427
+ S E ++ E AVS+ N YYS SAPKAELL K+K++ + EE+
Sbjct: 1721 QRTVSSSGCEGKRNEDK--EAVSMLVNCPAYYSVSAPKAELLNKIKEMPAEVNEEEEQA- 1777
Query: 1428 DLDHDLSVKKQELIESISRKLQVLREARESLLEDVQANTVLGAEVEAIVKGVCKPSEFDK 1487
D++ KK ELI S++ KL+ L+EA+ SLL D++ N LG EVEA++ +CKP+EFDK
Sbjct: 1778 ----DVNEKKAELIGSLTHKLETLQEAKGSLLTDIKLNNALGEEVEALISELCKPNEFDK 1833
Query: 1488 FRMFIGDLDKVVNLLLSLSGRLARVENALNNLDDGASPGDRQSLLEKQRVLIQQHEDAKE 1547
+RMFIGDLDKVVNLLLSLSGRLARVEN L+ L + AS +R SL EK+++L QHEDA+E
Sbjct: 1834 YRMFIGDLDKVVNLLLSLSGRLARVENVLSGLGEDASNEERSSLYEKRKILAGQHEDARE 1893
Query: 1548 LKENLDRRERIVFDILANYLSEESLADYEHFVKMKSALIIEQRELEDKIHLGEEQLKCLL 1607
LKENLDRRER+V ILANYLSEE L DY+HFVKMKS L+IEQR+L+DKI LG+EQ+KCLL
Sbjct: 1894 LKENLDRRERVVLGILANYLSEEQLQDYQHFVKMKSTLLIEQRKLDDKIKLGQEQVKCLL 1953
Query: 1608 DSL 1610
+SL
Sbjct: 1954 ESL 1956
Score = 186 bits (473), Expect = 1e-46
Identities = 148/406 (36%), Positives = 190/406 (46%), Gaps = 103/406 (25%)
Query: 14 AEAETRAADGGRLV--EVQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAV-DKLLA 70
A + A GR + E L GGAPWGFTLKGG EHGEPL+I+K+EEG KA + KL A
Sbjct: 13 ATLNSNTATKGRYIYLEAFLEGGAPWGFTLKGGLEHGEPLIISKVEEGGKADTLSSKLQA 72
Query: 71 GDEIVGINDIGLSGFRQEAICLVKGSHKTLKLVVK------------------------- 105
GDE+V IN++ LS R+EA+ LVKGS+KTL+LVV+
Sbjct: 73 GDEVVHINEVTLSSSRKEAVSLVKGSYKTLRLVVRRDVCTDPGHADTGASNFVSPEHLTS 132
Query: 106 -------------------RRSELGWRPHSWHATKFSDSHPELAASPFTSTSGCPSWSGR 146
RRSE RPHSWH TK + P+ + + P W
Sbjct: 133 GPQHRKAAWSGGVKLRLKHRRSEPAGRPHSWHTTKSGEKQPDASMMQISQGMIGPPWHQS 192
Query: 147 HHASSSSHDLSSSWEQTNLQRTLDHFSSLGSVDSLD----HPSSRLSVAKSNSSIDHLGS 202
+H+SSS+ DL S+++ L+R+ D SS GS++SL+ +P LS AKS SID L
Sbjct: 193 YHSSSSTSDL-SNYDHAYLRRSPDQCSSQGSMESLEPSGAYPPCHLSPAKSTGSIDQLSH 251
Query: 203 -HSKRDSAYGSFSTSSST---PDHTLSKADTS-SAENILYTVGLWEAPRQG--------- 248
H+KRDSAY SFSTSSS P +S + S S +N GL E RQ
Sbjct: 252 FHNKRDSAYSSFSTSSSILEYPHPGISGRERSGSMDNTSARGGLLEGMRQADIRYVKTVY 311
Query: 249 --------------------GRQAQAAGDPQGSEEKLSCFPPRVPGDSGKGPRPEYNAEP 288
GR+A+A+ + QG +K S P GKG P
Sbjct: 312 DTRRGVSAEYEVNSSALLLQGREARASANGQG-YDKWSNIP------RGKGVPP------ 358
Query: 289 KLAAPGRSNFGPVWYVPDKKKAPSSPPPPPPPLRSDSFAATKSHEK 334
P S P P P PP RSDS+AA + E+
Sbjct: 359 ----PSWSQQCPSSLETATDNLPPKVGAPLPPARSDSYAAFRHRER 400
Score = 32.7 bits (73), Expect = 2.9
Identities = 42/166 (25%), Positives = 58/166 (34%), Gaps = 41/166 (24%)
Query: 311 PSSPPPPPPPLRS------DSFAATKSHEKAQGPVFSEAAAAQHFTALAQAQPRGDRRPE 364
P PPPPPPP + D F H + + SE P G R
Sbjct: 1525 PLPPPPPPPPSQETPVYSMDDFPPPPPHTVCEAQLDSE-------------DPEGPR--- 1568
Query: 365 LTDRPWRSAHPGSLGKGSGGPGCPQEAHADGSWPPSKDGASSRLQASLSSSDVRFPQSPH 424
+ ++ + PG AH GS +SRLQ S+ S+
Sbjct: 1569 ---PSFNKLSKVTIARERHMPGA---AHVVGS-----QTLASRLQTSIKGSEA------- 1610
Query: 425 SGRHPPLYSDHSPLCADSLGQEPGAASFQNDSPPQVRGLSSCDQKL 470
P S H+ L A SLG +P Q+ S V G ++K+
Sbjct: 1611 ESTPPSFMSVHAQL-AGSLGGQPAPIQTQSLSHDPVSGTQGLEKKV 1655
>gi|118600967 shroom family member 4 [Homo sapiens]
Length = 1493
Score = 250 bits (638), Expect = 9e-66
Identities = 139/245 (56%), Positives = 179/245 (73%), Gaps = 17/245 (6%)
Query: 1376 STEERKEE----------PSVPAAVSLATNSTYYSTSAPKAELLIKMKDLQEQQEHEEDS 1425
+TE K+E P +P + S YY+ S KAELL K+KD E E
Sbjct: 1249 ATESAKQEFQHFSPPSGAPGIPTSYS-----AYYNISVAKAELLNKLKDQPEMAEIGLGE 1303
Query: 1426 GSDLDHDLSVKKQELIESISRKLQVLREARESLLEDVQANTVLGAEVEAIVKGVCKPSEF 1485
++DH+L+ KK +LIESISRKL VLREA+ LLED+ AN+ LG EVEA +K VCK +EF
Sbjct: 1304 -EEVDHELAQKKIQLIESISRKLSVLREAQRGLLEDINANSALGEEVEANLKAVCKSNEF 1362
Query: 1486 DKFRMFIGDLDKVVNLLLSLSGRLARVENALNNLDDGASPGDRQSLLEKQRVLIQQHEDA 1545
+K+ +F+GDLDKVVNLLLSLSGRLARVENALN++D A+ ++ L+EK++ L Q DA
Sbjct: 1363 EKYHLFVGDLDKVVNLLLSLSGRLARVENALNSIDSEANQ-EKLVLIEKKQQLTGQLADA 1421
Query: 1546 KELKENLDRRERIVFDILANYLSEESLADYEHFVKMKSALIIEQRELEDKIHLGEEQLKC 1605
KELKE++DRRE++VF +++ YL ++ L DY+HFVKMKSALIIEQRELE+KI LGEEQLKC
Sbjct: 1422 KELKEHVDRREKLVFGMVSRYLPQDQLQDYQHFVKMKSALIIEQRELEEKIKLGEEQLKC 1481
Query: 1606 LLDSL 1610
L +SL
Sbjct: 1482 LRESL 1486
Score = 192 bits (489), Expect = 2e-48
Identities = 191/644 (29%), Positives = 280/644 (43%), Gaps = 64/644 (9%)
Query: 27 VEVQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEIVGINDIGLSGFR 86
V VQL GGAPWGFTLKGG EH EPL ++KIE+G KAA K+ GDE+V IN L G R
Sbjct: 11 VPVQLQGGAPWGFTLKGGLEHCEPLTVSKIEDGGKAALSQKMRTGDELVNINGTPLYGSR 70
Query: 87 QEAICLVKGSHKTLKLVVKRRSELGWRPHSWHATKFSDSHPELAAS-PFTSTSGCPSWSG 145
QEA+ L+KGS + LKL+V+RR+ RPHSWH K + PE A + F S + SW
Sbjct: 71 QEALILIKGSFRILKLIVRRRNAPVSRPHSWHVAKLLEGCPEAATTMHFPSEAFSLSW-- 128
Query: 146 RHHASSSSHDLSSSWEQTNLQRTLDHFSSLGSVDSLDHPSSRLSVAKSNSSIDHLGSHSK 205
H+ ++ D+ W + + + SS+GS++SL+ P + + ID ++
Sbjct: 129 --HSGCNTSDVCVQWCPLSRHCSTEKSSSIGSMESLEQP-GQATYESHLLPIDQNMYPNQ 185
Query: 206 RDSAYGSFSTSSSTPDHTLS--KADTSSAENILYTVGLWEAPRQGGRQAQAAGDPQGSEE 263
RDSAY SFS SS+ D LS + +S + I+ G +AP GR A + G
Sbjct: 186 RDSAYSSFSASSNASDCALSLRPEEPASTDCIMQGPGPTKAP--SGRPNVA--ETSGGSR 241
Query: 264 KLSCFPPRVPGDSGKGPRPEYNAEPKLAAPGRSNFGPVWYVPDKKKAPSSPPPPPPPLRS 323
+ + P+ Y + P A G PP PP+R
Sbjct: 242 RTNGGHLTPSSQMSSRPQEGYQSGPAKAVRG---------------------PPQPPVRR 280
Query: 324 DSFAATKSHEKAQGPVFSEAAAAQHFTALAQAQPRGDRRPELTDRPWRSAHPGSLGKGSG 383
DS A+ +AQ + A++ L Q + + P L R +P SG
Sbjct: 281 DSLQAS----RAQLLNGEQRRASEPVVPLPQKE-KLSLEPVLPAR-----NPNRFCCLSG 330
Query: 384 GPGCPQEAHADGSW---PPSKDGASSRLQASLSSSDVRFPQS---PHSGRHPPLYSDHSP 437
E H + + P S S L S+ V P++ S PL +
Sbjct: 331 HDQVTSEGHQNCEFSQPPESSQQGSEHLLMQASTKAVGSPKACDRASSVDSNPLNEASAE 390
Query: 438 LCADSLGQEP---GAASFQNDSPPQVRGLSSCDQKLGSGWQGPRPCVQGDLQAAQLWAGC 494
L S G+ P G ++ +P Q+ L+S Q + +G + +Q W
Sbjct: 391 LAKASFGRPPHLIGPTGHRHSAPEQL--LASHLQHVHLDTRGSKGMELPPVQDGHQWT-L 447
Query: 495 WPSDTALGALESLPPPTVGQSPRHHLPQPEGPPDAR-----ETGRCYPLDKGAEG--CSA 547
P ++ +S PPT G + + D R + P A+G
Sbjct: 448 SPLHSSHKGKKSPCPPTGGTHDQSSKERKTRQVDDRSLVLGHQSQSSPPHGEADGHPSEK 507
Query: 548 GAQEPPRASRA--EKASQRLAASITWADGESSRICPQETPLLHSLTQEGKRRPESSPEDS 605
G +P R SRA E A+Q+ +AS + + + +EG P+
Sbjct: 508 GFLDPNRTSRAASELANQQPSASGSLVQQATDCSSTTKAASGTEAGEEGDSEPKECSRMG 567
Query: 606 ATRPPPFDAHVGKPTRRSDRFATTLRNEIQMHRAKLQKSRSTVA 649
R + R+S+RFAT LRNEIQ +A+LQKS+ ++
Sbjct: 568 GRRSGGTRGRSIQNRRKSERFATNLRNEIQRRKAQLQKSKGPLS 611
>gi|31442420 shroom family member 1 [Homo sapiens]
Length = 847
Score = 117 bits (294), Expect = 7e-26
Identities = 94/301 (31%), Positives = 150/301 (49%), Gaps = 31/301 (10%)
Query: 1317 EELAREIVGKDKSLADILDPSVKIKTTMDLMEGIFPKDEHLLEEAQQRRKLLPKIPSPRS 1376
EEL +E+ D SL D L + + L++G+ P A+ R + P +
Sbjct: 543 EELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIPL-------AEVRAAMRP------A 589
Query: 1377 TEERKEEPSVPAAVSLATNSTYYSTS----APKAELLIKMKDLQEQQEHEEDSGSDL--- 1429
E EE AA + S +S + AP+ E ++++ ++ G L
Sbjct: 590 CGEAGEE----AASTFEPGSYQFSFTQLLPAPREET--RLENPATHPVLDQPCGQGLPAP 643
Query: 1430 DHDLSVKKQELIESISRKLQVLREARESLLEDVQANTVLGAEVEAIVKGVCKPSEFDKFR 1489
++ + KK EL + + LQ L +E L + QA A +EA V+ C P E ++F
Sbjct: 644 NNSIQGKKVELAARLQKMLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFS 703
Query: 1490 MFIGDLDKVVNLLLSLSGRLARVENALNNLDDGASPGDRQSLLEKQRVLIQQHEDAKELK 1549
F+ DL++V+ LLL L RLARV AL + P + ++ R+L +Q EDAKELK
Sbjct: 704 RFMADLERVLGLLLLLGSRLARVRRALARAASDSDPDE-----QRLRLLQRQEEDAKELK 758
Query: 1550 ENLDRRERIVFDILANYLSEESLADYEHFVKMKSALIIEQRELEDKIHLGEEQLKCLLDS 1609
E++ RRER V ++L L E L Y + K+A++ +QR L+++I L ++QL + D
Sbjct: 759 EHVARRERAVREVLVRALPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDD 818
Query: 1610 L 1610
L
Sbjct: 819 L 819
Score = 50.8 bits (120), Expect = 1e-05
Identities = 110/477 (23%), Positives = 164/477 (34%), Gaps = 100/477 (20%)
Query: 178 VDSLDHPSSRLSVAKSNSSIDHLGSHSKRDSAYGSFSTSSSTPDHTLSKADTSSAENI-- 235
+++L R S A S SS+D + DSAY SFS +S P+ T +
Sbjct: 1 MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDW 60
Query: 236 LYTVGLWEAPRQGGRQAQAAGDPQGSEEKLSCFPPRVPGDSGKGPRPEYNAEPKLAAPGR 295
Y +W P A P+ PR + GP+P P P
Sbjct: 61 DYVRVVWGGPGPAPPDAALCTSPR----------PRPAVAARSGPQP--TEVPGTPGPLN 108
Query: 296 SNFGPVWY--VPDKKKAPSSPPPPPPPLRSDSFAATKSHEKAQGPVFSEAAAAQ---HFT 350
P+ Y + + A + PP PP + A + + AQ V E + + +
Sbjct: 109 RQATPLLYALAAEAEAAAQAVEPPSPP--ASRAAYRQRLQGAQRRVLRETSFQRKELRMS 166
Query: 351 ALAQAQPRGDRRPELT-DRPWRSAHPGSLGK-------GSGGPGCPQEAHADGSWPPSKD 402
A+ +P RP T R +HPG G+ G G A+ W S+
Sbjct: 167 LPARLRPTVPARPPATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEP 226
Query: 403 GASSR-----------LQASLSSSDVRFPQSPHSGRHPPL--YSDH------SPLCADSL 443
G R L + SSS + P+ P +HP L + DH S+
Sbjct: 227 GKLDRVGRGGGPARECLGEACSSSGLPGPE-PLEFQHPALAKFEDHEVGWLPETQPQGSM 285
Query: 444 GQEPGAASFQNDSPPQVRGLSSCDQKLGS--GWQGPRPCVQGDLQAAQLWAGCWPSDTAL 501
+ G+ + P R S+ + LGS G G P VQ Q A+
Sbjct: 286 NLDSGSLKLGDAFRPASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAE------------ 333
Query: 502 GALESLPPPTVGQSPRHHLPQPEGPPDARETGRCYPLDKGAEGCSAGAQEPPRASRAEKA 561
P P LPQ +E YP E P++S A+ +
Sbjct: 334 -----TPRPLFQTKLSRFLPQ-------KEAAVMYP------------AELPQSSPAD-S 368
Query: 562 SQRLAASI---TWADGESSRICPQETPLLHSLTQEGKRRPESSPEDSATRPPPFDAH 615
QR++ + W + +E PL+ R S P+ A++ PP H
Sbjct: 369 EQRVSETCIVPAWLPSLPDEVFLEEAPLV---------RMRSPPDPHASQGPPASVH 416
Score = 39.3 bits (90), Expect = 0.031
Identities = 34/105 (32%), Positives = 48/105 (45%), Gaps = 11/105 (10%)
Query: 680 YKDHLKEAQARVLRATSFKRRDLDPNPGDLYPESLEHRMGDPDTVPHFWEAGLAQP---- 735
Y+ L+ AQ RVLR TSF+R++L + P L + H A L+ P
Sbjct: 141 YRQRLQGAQRRVLRETSFQRKELRMS----LPARLRPTVPARPPATHPRSASLSHPGGEG 196
Query: 736 PSSTSGGPHPPRIGGRRRFTAEQKLKSYSEPEKMNEVGLTRGYSP 780
+ S P P GR +Q+ +SEP K++ VG RG P
Sbjct: 197 EPARSRAP-APGTAGRGPLANQQRKWCFSEPGKLDRVG--RGGGP 238
>gi|38201621 eukaryotic translation initiation factor 4 gamma, 1
isoform 1 [Homo sapiens]
Length = 1599
Score = 62.8 bits (151), Expect = 3e-09
Identities = 115/528 (21%), Positives = 189/528 (35%), Gaps = 91/528 (17%)
Query: 939 QAGDPGEPREEL-PSAVRAEEGQSTPRQADAQCREGSPGSQQHPPSQKAPNPPTFSELSH 997
Q P +PR+ PS + ++ Q+ A R G P + +P + P+
Sbjct: 40 QMNTPSQPRQHFYPSRAQPPSSAASRVQSAAPARPG-PAAHVYPAGSQVMMIPSQISYPA 98
Query: 998 CRGAPELPREGRGRAGTLPRDY-------RYSEESTPADLGPRAQSPGSPLHARGQDSWP 1050
+GA +P +GR + Y + ++P + G A G+ A+G +P
Sbjct: 99 SQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYA---GAYYPAQGVQQFP 155
Query: 1051 VSSALLSKRPAP---QRPP--PPKREPRRYRATD----GAPADAPVGVLGRPFPTPSPAS 1101
A PAP +PP PKRE + R D G + R TP+P
Sbjct: 156 TGVA-----PAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQ 210
Query: 1102 LDVYVARLSLSHSPSVFSSAQPQDTPKATVCERGSQHVSGDASRPLPEALLPPKQQHLRL 1161
+ + +P V +P D + + A RP L P+
Sbjct: 211 TGGGLEPQANGETPQVAVIVRPDDRSQGAII----------ADRP---GLPGPEHSPSES 257
Query: 1162 QTATMETSRSPSPQFAPQKLTDKPPLLIQDEDSTRIERVMDNNTTVK------------- 1208
Q ++ + SPSP P + L I + T I+ ++ +T +
Sbjct: 258 QPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEP 317
Query: 1209 ------MVPIKIVHSESQPEKESRQSLACPAEPPALPHGLEKDQIKTLSTSEQFYSRFCL 1262
++ +++ S+ PE E S A P H +E + + SE L
Sbjct: 318 TPLAEPILEVEVTLSKPVPESEFSSS-PLQAPTPLASHTVEIHEPNGMVPSED------L 370
Query: 1263 YTRQGAEPE-APHRAQPAE-PQPLGTQVPPEK--DRCTSPPGLSYMKAKEKTVEDLKSEE 1318
+ PE AP A P+E P P+ PE+ + SPP + E EE
Sbjct: 371 EPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSE-------PEE 423
Query: 1319 LAREIVGKDKSLADILDPSVKIKTTMDLMEGIFPKDEHLLEEAQQRRK----LLPKIPSP 1374
A+E+ A + P++ T P E +EE ++ + + S
Sbjct: 424 QAKEVT------ASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESE 477
Query: 1375 RSTEERKEEPSVPAAVSLATN-----STYYSTSAPKAELLIKMKDLQE 1417
+ EE S P +L+ N +T + S PK IK + +E
Sbjct: 478 KGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKE 525
Score = 31.2 bits (69), Expect = 8.5
Identities = 15/40 (37%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Query: 363 PELTDRPWRSAHPGSLGKGSGGPGCPQEAHADGSWPPSKD 402
PE+ ++P ++PG +GSG P P+E AD +W +D
Sbjct: 542 PEVENQPPAGSNPGPESEGSGVPPRPEE--ADETWDSKED 579
>gi|38201623 eukaryotic translation initiation factor 4 gamma, 1
isoform 1 [Homo sapiens]
Length = 1599
Score = 62.8 bits (151), Expect = 3e-09
Identities = 115/528 (21%), Positives = 189/528 (35%), Gaps = 91/528 (17%)
Query: 939 QAGDPGEPREEL-PSAVRAEEGQSTPRQADAQCREGSPGSQQHPPSQKAPNPPTFSELSH 997
Q P +PR+ PS + ++ Q+ A R G P + +P + P+
Sbjct: 40 QMNTPSQPRQHFYPSRAQPPSSAASRVQSAAPARPG-PAAHVYPAGSQVMMIPSQISYPA 98
Query: 998 CRGAPELPREGRGRAGTLPRDY-------RYSEESTPADLGPRAQSPGSPLHARGQDSWP 1050
+GA +P +GR + Y + ++P + G A G+ A+G +P
Sbjct: 99 SQGAYYIPGQGRSTYVVPTQQYPVQPGAPGFYPGASPTEFGTYA---GAYYPAQGVQQFP 155
Query: 1051 VSSALLSKRPAP---QRPP--PPKREPRRYRATD----GAPADAPVGVLGRPFPTPSPAS 1101
A PAP +PP PKRE + R D G + R TP+P
Sbjct: 156 TGVA-----PAPVLMNQPPQIAPKRERKTIRIRDPNQGGKDITEEIMSGARTASTPTPPQ 210
Query: 1102 LDVYVARLSLSHSPSVFSSAQPQDTPKATVCERGSQHVSGDASRPLPEALLPPKQQHLRL 1161
+ + +P V +P D + + A RP L P+
Sbjct: 211 TGGGLEPQANGETPQVAVIVRPDDRSQGAII----------ADRP---GLPGPEHSPSES 257
Query: 1162 QTATMETSRSPSPQFAPQKLTDKPPLLIQDEDSTRIERVMDNNTTVK------------- 1208
Q ++ + SPSP P + L I + T I+ ++ +T +
Sbjct: 258 QPSSPSPTPSPSPVLEPGSEPNLAVLSIPGDTMTTIQMSVEESTPISRETGEPYRLSPEP 317
Query: 1209 ------MVPIKIVHSESQPEKESRQSLACPAEPPALPHGLEKDQIKTLSTSEQFYSRFCL 1262
++ +++ S+ PE E S A P H +E + + SE L
Sbjct: 318 TPLAEPILEVEVTLSKPVPESEFSSS-PLQAPTPLASHTVEIHEPNGMVPSED------L 370
Query: 1263 YTRQGAEPE-APHRAQPAE-PQPLGTQVPPEK--DRCTSPPGLSYMKAKEKTVEDLKSEE 1318
+ PE AP A P+E P P+ PE+ + SPP + E EE
Sbjct: 371 EPEVESSPELAPPPACPSESPVPIAPTAQPEELLNGAPSPPAVDLSPVSE-------PEE 423
Query: 1319 LAREIVGKDKSLADILDPSVKIKTTMDLMEGIFPKDEHLLEEAQQRRK----LLPKIPSP 1374
A+E+ A + P++ T P E +EE ++ + + S
Sbjct: 424 QAKEVT------ASMAPPTIPSATPATAPSATSPAQEEEMEEEEEEEEGEAGEAGEAESE 477
Query: 1375 RSTEERKEEPSVPAAVSLATN-----STYYSTSAPKAELLIKMKDLQE 1417
+ EE S P +L+ N +T + S PK IK + +E
Sbjct: 478 KGGEELLPPESTPIPANLSQNLEAAAATQVAVSVPKRRRKIKELNKKE 525
Score = 31.2 bits (69), Expect = 8.5
Identities = 15/40 (37%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Query: 363 PELTDRPWRSAHPGSLGKGSGGPGCPQEAHADGSWPPSKD 402
PE+ ++P ++PG +GSG P P+E AD +W +D
Sbjct: 542 PEVENQPPAGSNPGPESEGSGVPPRPEE--ADETWDSKED 579
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 61.2 bits (147), Expect = 8e-09
Identities = 143/724 (19%), Positives = 237/724 (32%), Gaps = 122/724 (16%)
Query: 747 RIGGRRRFTAEQKLKSYSEPEKMNEVGLTRGYSPHQHPRTSEDTVGTFADRWKFFEETSK 806
R + R + S++ P + + +R YSP + P +
Sbjct: 279 RSRSKSRSRTRSRSPSHTRPRRRHR-SRSRSYSPRRRPSPRR-----------------R 320
Query: 807 PVPQRPAQKQALHGIPRDKPERPRTAGRTCEGTEPWSRTTSLGDSLNAHSAAEKAG--TS 864
P P+R + + PR + R R + S ++S S + S +K TS
Sbjct: 321 PSPRRRTPPRRMPPPPRHRRSRSPVRRRR-RSSASLSGSSSSSSSSRSRSPPKKPPKRTS 379
Query: 865 DLPRRLGTFAEYQASWKEQRKPLEA-------------RSSGRCHSADDILDVSLDPQER 911
PR+ + + + + +P + S R + + +
Sbjct: 380 SPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKV 439
Query: 912 PQHVHGRSRSSPSTDHYKQEASVELRRQAGDPGEPREELPSAVRAEEGQSTPRQADAQCR 971
+H R SPS + VEL D G S + + + +Q+ +
Sbjct: 440 TKHKGTEKRESPSPA--PKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSG 497
Query: 972 EGSPGSQQHPPSQKAPNPPTFSELSHCRGAPELPREGRGRAGTLPRDYRYSEESTPADLG 1031
S + P N H P + + T PR R S P
Sbjct: 498 SSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRR 557
Query: 1032 PRAQSPGSPLHARGQDSWPVSSALLSKRPAPQRPPPPKREP---RRYRATDGAPADAPVG 1088
R+ SP P R + P S P + P P + P RRY +P+ P
Sbjct: 558 RRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRY-----SPSPPPKR 612
Query: 1089 VLGRPFPTPSPASLDVYVARLSLSHSPSVFSSAQPQDTPKATVCERGSQHVSGDA-SRPL 1147
P P P + + +SHSP + P K S+H G + SR
Sbjct: 613 RTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSP--VTKRRSPSLSSKHRKGSSPSRST 670
Query: 1148 PEALLP-PKQQHLRLQTATMETSRSPSPQFAPQKLTDKPPLLIQDEDSTRIERVMDNNTT 1206
EA P P ++H S SP P+ APQ + PP+ S + + +T
Sbjct: 671 REARSPQPNKRH----------SPSPRPR-APQTSSSPPPVRRGASSSPQRRQSPSPSTR 719
Query: 1207 VKMVPIKIVHSESQPEKESRQSLACPAEPPALPHGLEKDQIKTLSTSEQFYSRFCLYTRQ 1266
PI+ V +P+K + + P ++ +S+S
Sbjct: 720 ----PIRRVSRTPEPKKIKKAASPSP------------QSVRRVSSSRSV---------- 753
Query: 1267 GAEPEAPHRAQPAEPQPLGTQVPPEKDRCTSPPGLSYMKAKEKTVEDLKSEELAREIVGK 1326
PE + PA P P+ +Q P P + KAK T +E GK
Sbjct: 754 SGSPEPAAKKPPAPPSPVQSQSP----STNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGK 809
Query: 1327 DKSLADILDPSVKIKTTMDLMEGIFPKDEHLLEEAQQRRKLLPKIPSPRSTEERKEEPSV 1386
K K + + ++ K K ++
Sbjct: 810 KKK-----------------------KKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVT 846
Query: 1387 PAAVSLATNSTYYSTSAPKAELLIKMKDLQEQQEHEEDSGSDLDHDLSVKKQELIESISR 1446
PAA++ AT T+ + E + + +E + ED+ DL+ L +++ + S+ R
Sbjct: 847 PAAIAAAT------TTLAQEEPVAAPEPKKETESEAEDNLDDLEKHL---REKALRSM-R 896
Query: 1447 KLQV 1450
K QV
Sbjct: 897 KAQV 900
Score = 40.4 bits (93), Expect = 0.014
Identities = 78/352 (22%), Positives = 123/352 (34%), Gaps = 43/352 (12%)
Query: 280 PRPEYNAEPKLAAPGRSNFGPVWYVPDKKKAPSSPPPPPPPLRSDSFAATKSHEKAQGPV 339
PR + + + P + + P P K+ +SPPPPP S S + + P
Sbjct: 586 PRRRSPSPRRYSPPIQRRYSPS---PPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPK 642
Query: 340 FSEAAAAQHFTALAQAQPRGDRRPELTDRPWRSAHPGSLGKGSGGPGCPQEAHADGSWPP 399
+ + + ++ R P + R RS P S P PQ S PP
Sbjct: 643 QRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQ---TSSSPPP 699
Query: 400 SKDGASSRLQASLSSSDVRFPQSPHSGRHPPLYSDHSPLCADSLGQEPGAASFQNDSPPQ 459
+ GASS Q QSP P +P + + SP
Sbjct: 700 VRRGASSSPQRR---------QSPSPSTRPIRRVSRTP-------EPKKIKKAASPSPQS 743
Query: 460 VRGLSSCDQKLGSGWQGPR--PCVQGDLQAAQLWAGCWPSDTALGALESLPPPTVGQSPR 517
VR +SS GS + P +Q+ P+ A P P+ PR
Sbjct: 744 VRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPS---PPR 800
Query: 518 HHLPQPEGPPDARETGRCYPLDKGAEGCSAGAQEPPRASRAEKA-SQRLAASIT-WADGE 575
+ + G ++ + + DK + + + EKA + AA++T A
Sbjct: 801 NSDQEGGGKKKKKKKDKKHKKDK--------KHKKHKKHKKEKAVAAAAAAAVTPAAIAA 852
Query: 576 SSRICPQETPLLHSLTQEGKRRPESSPEDSATRPPPFDAHVGKPTRRSDRFA 627
++ QE P+ E K+ ES ED+ + H+ + RS R A
Sbjct: 853 ATTTLAQEEPV---AAPEPKKETESEAEDNL---DDLEKHLREKALRSMRKA 898
Score = 39.7 bits (91), Expect = 0.024
Identities = 67/288 (23%), Positives = 104/288 (36%), Gaps = 49/288 (17%)
Query: 918 RSRSSPSTDHYKQEASVE-LRRQAGDPGEPREELPSAVRAEEGQSTPRQADAQCREGSPG 976
R + + K+E S RR++ P R P + S + + R SP
Sbjct: 154 RDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPA 213
Query: 977 SQQHPPSQKAPNP------PTFSELSHCRGAPELP-----------------REGRGRAG 1013
++ + + P P P+ E + ++P ++ + +
Sbjct: 214 PEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEK 273
Query: 1014 TLPRD-YRYSEESTPADLGPRAQSPGSPLHARGQDSWPVSSALLSKRPAPQRPPPPKR-- 1070
T PR R S P P +R + P +RP+P+R PP+R
Sbjct: 274 TRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMP 333
Query: 1071 EPRRYRATDGAPADAPVGVLGRPFPTPSPASLDVYVARLSLSHSPSVFSSAQPQDTPKAT 1130
P R+R + +PV R S ASL S S S S S + P+ PK T
Sbjct: 334 PPPRHRR-----SRSPVRRRRR-----SSASLSG-----SSSSSSSSRSRSPPKKPPKRT 378
Query: 1131 VC-ERGSQHVSGDAS------RPLPEALLPPKQQHLRLQTATMETSRS 1171
R ++ +S AS RP P A PPK +H + T +S
Sbjct: 379 SSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKS 426
Score = 33.9 bits (76), Expect = 1.3
Identities = 80/391 (20%), Positives = 117/391 (29%), Gaps = 48/391 (12%)
Query: 246 RQGGRQAQAAGDPQGSEEKLSCFPPRVPGDSGKGPRPEYNAEPKLAAPGRSNFGPVWYVP 305
R+ A +G S S PP+ P P + A+P P
Sbjct: 347 RRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASP-----------P 395
Query: 306 DKKKAPSSPPPPPPPLRSDSFAATKSHEKAQGPVFSEAAAAQHFTALAQAQPRGDRRPEL 365
++ PS P PPP R + + S + T + R P
Sbjct: 396 RRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKR--ESPSP 453
Query: 366 TDRPWRSAHPGSLGKGSGGPGCPQEAHADGSWPPSKDGASSRLQASLSSSDVRFPQSPHS 425
+P + S G + +SS +S SS D R +S
Sbjct: 454 APKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVK 513
Query: 426 GRHPPLYSDHSPLCADSLGQEPGAASFQNDSPPQVRGLSSCDQKLGSGWQGPRPCVQGDL 485
HSP S P Q ++ P+ R S + P P
Sbjct: 514 NGEVGRRRRHSP----SRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRR 569
Query: 486 QAAQLWAGCWPSDTALGALESLPPPTVGQSPRHHLPQPE-----GPPDARETGRCYPLDK 540
+ P+ S PP SPR + P + PP R T P K
Sbjct: 570 RRT-------PTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPK 622
Query: 541 GAEGCSAGAQEPP--RASRAEKASQRLAASITWADGESSRICPQETPLLHSLTQEGKRRP 598
A PP R S + QR SS + + +P L S ++G
Sbjct: 623 R----RASPSPPPKRRVSHSPPPKQR-----------SSPVTKRRSPSLSSKHRKGSSPS 667
Query: 599 ESSPEDSATRPPPFDAHVGKPTRRSDRFATT 629
S+ E A P P H P R+ + +++
Sbjct: 668 RSTRE--ARSPQPNKRHSPSPRPRAPQTSSS 696
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 60.1 bits (144), Expect = 2e-08
Identities = 230/1044 (22%), Positives = 328/1044 (31%), Gaps = 152/1044 (14%)
Query: 116 SWHATKFSDSHPELAASPFTSTS-GCP----------SWSGRHHASSSSHDLSSSW-EQT 163
SW FS H EL+ SP S G P + +S DL+ + Q
Sbjct: 1304 SWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQL 1363
Query: 164 NLQRTLDHFSSLGSVDSLDHPSSRLSVAKSNSSIDHLGSHSKRDSAYGSFSTSSSTPDHT 223
+LD S S H SS L S +++ G S + + TP
Sbjct: 1364 ETDPSLDMKEQ--STRSSGHSSSEL----SPDAVEKAGMSSNQSISSPVLDAVPRTP--- 1414
Query: 224 LSKADTSSAENILYTVGLWEAPRQGGRQAQAAGDPQGSEEKLSCFPPRVPGDSGKGPRPE 283
S+ +SSA + GL P + R + G GS P R S G P
Sbjct: 1415 -SRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGT-----PSR---HSLSGSSPG 1465
Query: 284 YNAEPKLAAPGRSNFGPVWYVPDKKKAPSSP-----PPPPPPLRSDSFAATKSHEKAQGP 338
P+ + GRS P+ K P +P P P L + + ++
Sbjct: 1466 MKDIPRTPSRGRSECDS---SPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESS 1522
Query: 339 VFSEAAAAQHFTALAQAQPRGDRRPELTDRPWRSAHPGSLGKGSGGPGCPQEAHADGSWP 398
V + A T L Q G + EL +P S PQE S P
Sbjct: 1523 VDQKTVAR---TPLGQRSRSGSSQ-ELDVKPSAS---------------PQERSESDSSP 1563
Query: 399 PSKDGASSRL-QASLSSS----DVRFPQSPHSGRHPPLYSDHSPLCADSLGQEPGAASFQ 453
SK + L Q S S S D + SP R S SP D P A S
Sbjct: 1564 DSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSR-----SGSSPEVKDKPRAAPRAQSGS 1618
Query: 454 NDSP----PQVRGLSSCDQKLGSGWQGPRPCVQGDLQAAQLWAGCWPSDTA-LGALESLP 508
+ SP P R L + GS +G P +G S TA G+ S
Sbjct: 1619 DSSPEPKAPAPRALPR-RSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPE 1677
Query: 509 PPTVGQSPRHHLPQPEGPPDARETGRCYPLDKGAEGCSAGAQEPPRASRAEKASQRLAAS 568
P T ++P P R+ + ++ PPR R+ S A
Sbjct: 1678 PKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAE 1737
Query: 569 ITWADGESSRICPQETPLLHSLTQEGKRRPESSPEDSATRPPPFDAHVGKPTRRSDRFAT 628
S R +P + ++ G R P P + TRR DR +
Sbjct: 1738 ---KSRSSRRRRSASSPRTKTTSRRG-RSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGS 1793
Query: 629 TLRNEIQMHRAKLQKSRSTVALTAAGEAEDGTGRWRAGLGGGTQEGPLAGTYKDHLKEAQ 688
+ Q + Q+SRS +T R R G G P A+
Sbjct: 1794 S-----QSTSRRRQRSRSRSRVT----------RRRRGGSGYHSRSP-----------AR 1827
Query: 689 ARVLRATSFKRRDLDPNPGDLYPESLEHRMGDPDTVPHFWEAGLAQPPSSTSGGPHPPRI 748
R +S +RR P P S + P A P + P I
Sbjct: 1828 QESSRTSSRRRRGRSRTP----PTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLI 1883
Query: 749 GGRR---RFTAEQKLKSYSEPEKMNEVGLTRGYSPHQHPRTSEDTVGTFADRWKFFEETS 805
RR R + + +S S +R SP R+ T R +
Sbjct: 1884 SRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRA-SPVSRRRSRSRTPPVTRRR----SRSR 1938
Query: 806 KPVPQRPAQKQALHGIPRDKPER--PRTAGRTCEGTEPWSRTTSLGDSLNAHSAAEKAGT 863
P +R ++ + R R P T R+ T P +R S + ++ T
Sbjct: 1939 TPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRT 1998
Query: 864 SDLPRRLGTFAEYQASWKEQRKPLEARSSGRCHSADDILDVSLDPQERPQHVHGRSRS-S 922
S + RR + + R R S +L P + RSRS +
Sbjct: 1999 SPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRT 2058
Query: 923 PSTDHYKQE-----ASVELRRQAGDPGE-PREELPSAVRAEEGQSTPRQADAQCREG--S 974
P T K+ ++ R +G + R P A R G TP A R S
Sbjct: 2059 PRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFS 2118
Query: 975 PGSQQHPPSQKAPNPPTFSELSHCRGAPELPREGRGRA--GTLPRDYRYSEESTPADLGP 1032
S P + +P L R + ++ G G PR + S P +
Sbjct: 2119 RPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPEN--- 2175
Query: 1033 RAQSPGSPLHARGQDSWPVSSALLSKRPAPQRPPPPKREPRRYRATDGAPA--------D 1084
HA+ + ++ AL + RPPP PA
Sbjct: 2176 ---------HAQSR----IALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRT 2222
Query: 1085 APVGVLGRPFPTPSPASLDVYVAR 1108
AP L P S A++++ AR
Sbjct: 2223 APAANLASRIPAASAAAMNLASAR 2246
Score = 57.0 bits (136), Expect = 1e-07
Identities = 222/1112 (19%), Positives = 363/1112 (32%), Gaps = 180/1112 (16%)
Query: 123 SDSHPELAASPFTSTSGCPSWSGRHHASSSSHDLSSSWEQTNLQRTLDHFSSLGSVDSLD 182
S+S PE+ S +S + S S S + + +L+R+L S S
Sbjct: 743 SNSSPEMKKSRISS----------RRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQT 792
Query: 183 HPSSRLSVAKSNSSIDHLGSHSKRDSAYGSFSTSSSTPDHTLSKADTSSAENILYTVGLW 242
P S + + R S+ S TP ++ +SS+ + G
Sbjct: 793 PPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSR---QSHSSSSPHPKVKSGT- 848
Query: 243 EAPRQGGRQAQAAGDPQGSEEKLSCFPPRVPGDSGKGPRPEYNAE-PKLAAPGRSNFGPV 301
PRQG + A + + ++ SCF P PE + P + S+ V
Sbjct: 849 -PPRQGSITSPQANEQSVTPQRRSCFE--------SSPDPELKSRTPSRHSCSGSSPPRV 899
Query: 302 WYVPDKKKAPSSPPPPPPPLRSDSFAATKSHEKAQGPVFSEAAAAQHFTALAQAQPRGDR 361
+++PS P P +++ +SH + P S + + PR R
Sbjct: 900 KSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTS--------RTTPRRSR 951
Query: 362 RPELTDRPWRSAHPGSLGKGSGGPGC-------PQEAHADGSWPPSKDGASSRLQASLSS 414
P GS P P+++H+ P K A + SLS
Sbjct: 952 SVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSG 1011
Query: 415 SDVRFPQSPHSGRHPPLYSDHSPLCADSLGQEPGAASFQNDSPPQVRGLSSCDQKLGSGW 474
S PQ LCA P S+ S Q++G S S
Sbjct: 1012 SKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDT 1071
Query: 475 QGPRPCVQGDLQAAQLWAGCWPSDTALGALESLPPPTVGQSPRHHLPQPEGPPDARETGR 534
P Q ++ L + S G P + R + Q G A
Sbjct: 1072 SSPE-VRQSHSESPSLQSKSQTSPK--GGRSRSSSPVTELASRSPIRQDRGEFSAS---- 1124
Query: 535 CYPLDKGAEGCSAGAQEPPRASRAEKASQRLAASITWADGESSRICPQETPLLHSLTQEG 594
P+ K P SR + S ++ +S+ + Q T E
Sbjct: 1125 --PMLKSGMS--------PEQSRFQSDSS------SYPTVDSNSLLGQS----RLETAES 1164
Query: 595 KRRPESSPEDSATRPPPFDAHVGKPTRRSDRFATTLRNEIQMHRAKLQKSRSTVALTAAG 654
K + P++ AT PP P DR ++L + + ++S AG
Sbjct: 1165 KEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERS-------GAG 1217
Query: 655 EAEDGTGRWRAGLGGGTQEGPLAGTYKDHLKEAQARVLRATSFKRRDLDPNPGDLYPESL 714
+ + T + L +Q+ L + +E ++L S + +++ + + PE +
Sbjct: 1218 SSPE-TKEQNSALPTSSQDEELMEVV-EKSEEPAGQILSHLSSELKEMSTSNFESSPE-V 1274
Query: 715 EHRMG-----DPDTVPHFWEAGLAQPPSSTSGGPHPPRIGGRRRFTAEQKLKSYSEPEKM 769
E R D EA +S+ GGPH F+ E K S S P +
Sbjct: 1275 EERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPH---------FSPEHKELSNS-PLRE 1324
Query: 770 NEVG--------------LTRGYSPHQHPRTSEDTVGTFADRWKFFEETSKPVPQRPAQK 815
N G + G+S ED G F ++ E + + +
Sbjct: 1325 NSFGSPLEFRNSGPLGTEMNTGFS----SEVKEDLNGPFLNQ---LETDPSLDMKEQSTR 1377
Query: 816 QALHGIPRDKPERPRTAGRTCEGT------EPWSRTTSLGDSLNAHSAAEKAGTSDLPRR 869
+ H P+ AG + + + RT S S +A S K G P R
Sbjct: 1378 SSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSR 1437
Query: 870 LGTFAEYQASWKEQRKPLEARSSGRCHSADDI----------LDVSLDPQERPQHVHGRS 919
P SG DI D S +P+ PQ RS
Sbjct: 1438 RSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRS 1497
Query: 920 RSSPSTDHYKQEASVELRRQAGDPGEPREELPSAVRAEEGQSTPRQADAQCREGSPGSQQ 979
R SPS+ + R ++G E + + R GQ + R +Q + P +
Sbjct: 1498 R-SPSSPELNNKCLTPQRERSG--SESSVDQKTVARTPLGQRS-RSGSSQELDVKPSASP 1553
Query: 980 HPPSQKAPNPPTFSELSHCRGAPELPREGRGRAGTLPRDYRYSEESTPADLGPRAQSPGS 1039
S+ +P + + P R R+G+ P E + + L PR GS
Sbjct: 1554 QERSESDSSPDS-------KAKTRTPLRQRSRSGSSP------EVDSKSRLSPRRSRSGS 1600
Query: 1040 PLHARGQD-SWPVSSALLSKRPAPQRPPPPKREPRRYRATDGAPADAPVGVLGRPFPTPS 1098
+ + + P + + P P + P P+ PRR R+ + P
Sbjct: 1601 SPEVKDKPRAAPRAQSGSDSSPEP-KAPAPRALPRRSRSGSSSKGRGP------------ 1647
Query: 1099 PASLDVYVARLSLSHSPSVFSSAQPQDTPKATVCERGSQHVSGDASRPLPEALLPPKQQH 1158
S S + + P+ PK+ RGS+ + P ++ PP+++
Sbjct: 1648 -------------SPEGSSSTESSPEHPPKSRTARRGSR----SSPEPKTKSRTPPRRRS 1690
Query: 1159 LR----LQTATMETSRSPSPQFAPQKLTDKPP 1186
R L + RS S +P+ + PP
Sbjct: 1691 SRSSPELTRKARLSRRSRSASSSPETRSRTPP 1722
Score = 56.6 bits (135), Expect = 2e-07
Identities = 202/949 (21%), Positives = 312/949 (32%), Gaps = 148/949 (15%)
Query: 296 SNFGPVWYVPDKKKAPSSPPPPPPPLRSDSFAAT------KSHEKAQGPVFSEAAAAQHF 349
S+F P + K+ PP P +R S + + K +K SE+++ +
Sbjct: 149 SSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRE 208
Query: 350 TALAQAQPRGDRRPELTDRPWRSAHPGSLGKGSGGPGCPQEAHADGSWPPSKDGASSRLQ 409
+ + + E R RS P S K + + + P S+ S
Sbjct: 209 RKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKR--KRSRSTTPAPKSRRAHRSTSA 266
Query: 410 ASLSSSDVRFPQSPHSGR--HPPLYSDHSPLCA-------DSLGQEPGAASFQNDSPPQV 460
S SSSD +S + H + SP A D+ EPG S Q S P+
Sbjct: 267 DSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPET 326
Query: 461 RGLSSCDQKLGSGWQGPRPCVQGDLQAAQLWAGC-WPSDTALGALESLPPPTVGQSPRHH 519
+ Q P D + A PS P PT + RH
Sbjct: 327 -----------ATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHG 375
Query: 520 -LPQPEGPPDARETGRCYPLDKGAEGCSAGAQEPPRASRAEKASQRLAASITWADGESSR 578
PQP + P++ +E + PP K+ ++L S + ESS
Sbjct: 376 GSPQPLATTPLSQE----PVNPPSEASPTRDRSPP------KSPEKLPQS---SSSESSP 422
Query: 579 ICPQETPLLHSLTQEGKRRPESSPEDSATRPPPFDAHV--GKPTRRSDRFATTLRNEIQM 636
PQ T + R SSPE P P PT ++ R++
Sbjct: 423 PSPQPTKV--------SRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHS 474
Query: 637 HRAKLQKSRSTVALTAA------------GEAEDGTGRWR----AGLGGGTQEGPLAGTY 680
H + RS TA G + + +WR A G ++ G
Sbjct: 475 HTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRS 534
Query: 681 KDHLKEAQARVLRATSFKRRDLDPNPGDLYPESLEHRMGDPDTVPHFWEAGLAQPPS--- 737
+ + +R R T + R G + S R P ++ P+
Sbjct: 535 RSPQRPGWSRS-RNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRR 593
Query: 738 STSGGPH--------PPRIGGRRRFTAEQKLKSYSEPEKMNEVGLTRGYSPHQHPRTSED 789
S S P P R G R T ++ P + +R SP + R+
Sbjct: 594 SRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRR----SRSRSPAR--RSGRS 647
Query: 790 TVGTFADRWKFFEETSKPVPQRPAQKQALHGIPRDKPERPRTAGRTCEGTEPWSRTTSLG 849
T A R + T P R + ++ R R RT R SRT G
Sbjct: 648 RSRTPARRGRSRSRT----PARRGRSRSRTPARRSGRSRSRTPARRGRSR---SRTPRRG 700
Query: 850 DSLNAHSAAEKAGTSDLPRRLGTFAEYQASWKEQRKPLEARSSGRCHSADDILDVSLDPQ 909
S + S P+R G ++ +RK S R S + P+
Sbjct: 701 RSRSRSLVRRGRSHSRTPQRRG-----RSGSSSERKNKSRTSQRRSRS-------NSSPE 748
Query: 910 ERPQHVHGRSRSSPSTDHYKQEASVELRRQ--AGDPGEPREELPSAVRAEEGQSTPRQAD 967
+ + R S S+ K ++ + LRR P ++ R+ G S P+
Sbjct: 749 MKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKS 808
Query: 968 AQCREGSPGSQQHPPSQKAPNPPTFSELSHCRGAPELPREGRG---RAGTLPRDYRYSEE 1024
S S PP QK+ P S SH +P P+ G R G++ +
Sbjct: 809 RTPPRRSRSSSSPPPKQKSKTP---SRQSHSSSSPH-PKVKSGTPPRQGSITSPQANEQS 864
Query: 1025 STP-------ADLGPRAQSPGSPLHARGQDSWPVSSALLSKRPAPQRPPPPKREPR---- 1073
TP + P +S H+ S P + R +P R P+ + +
Sbjct: 865 VTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIIS 924
Query: 1074 -RYRATDGAPADAPVGVLGRPFP----TPSPAS--LDVYVARLSLSHSPSVFSSAQPQDT 1126
R R+ G+ + +P V R P + SP S + R S S S S + +P+
Sbjct: 925 PRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETP 984
Query: 1127 PKATVCERGSQHVSGDASRPLPEALLPPKQQHLRLQTATMETSRSPSPQ 1175
P+ H + P +A PP ++ S+SP PQ
Sbjct: 985 PR-------QSHSGSISPYPKVKAQTPP--------GPSLSGSKSPCPQ 1018
Score = 48.5 bits (114), Expect = 5e-05
Identities = 226/1092 (20%), Positives = 343/1092 (31%), Gaps = 181/1092 (16%)
Query: 177 SVDSLDHPSSRLSVAKSNSSIDHLGSHSKRDSAYGSFSTS-----SSTPDHTLSKADTSS 231
S+ S S + ++S+S + L S S G FS S +P+ + ++D+SS
Sbjct: 1085 SLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSS 1144
Query: 232 AENILYTVGLWEAPRQGGR---------QAQAAGDPQGSEEKLSCFPP------------ 270
+ L ++ + Q A P ++K S FP
Sbjct: 1145 YPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKD 1204
Query: 271 --RVPGD--SGKGPRPEYNAEPKLAAPGRSNFGPVWYVPDKKKAP--------------- 311
R P SG G PE E A P S + V +K + P
Sbjct: 1205 TLRTPPRERSGAGSSPE-TKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEM 1263
Query: 312 ------SSPPPPPPP---LRSDSFAATKSHEKAQGPVFSEAAAAQHFTALAQAQPRGDRR 362
SSP P L D + S E + P + + HF+ + R
Sbjct: 1264 STSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLR 1323
Query: 363 PELTDRPWRSAHPGSLGKGSGGPGCPQEAHADGSWP--------PSKDGASSRLQASLSS 414
P + G LG G E D + P PS D ++S S
Sbjct: 1324 ENSFGSPLEFRNSGPLGTEMN-TGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHS 1382
Query: 415 SDVRFPQSPHSGRHPPLYSDHSPLCADSLGQEPGAASFQNDSPPQVR-GLSSCDQKLGSG 473
S P + S SP+ D++ + P + S P+++ GL +
Sbjct: 1383 SSELSPDAVEKAGMSSNQSISSPVL-DAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRS 1441
Query: 474 WQGPRPCVQGDLQAAQLWAGCWPSDTALGALESLP-PPTVGQSPRHHLPQPEGPPDA-RE 531
P + +G P ++ +P P+ G+S P+P+ P R
Sbjct: 1442 GSSPGLRDGSGTPSRHSLSGSSPG------MKDIPRTPSRGRSECDSSPEPKALPQTPRP 1495
Query: 532 TGRCYPLDKGAEGCSAGAQEPPRASRAEKASQRLAASITWADGESSRICPQETPLLHSLT 591
R + C +E R+ Q+ A G+ SR +
Sbjct: 1496 RSRSPSSPELNNKCLTPQRE--RSGSESSVDQKTVARTPL--GQRSR---------SGSS 1542
Query: 592 QEGKRRPESSPED--SATRPPPFDAHVGKPTRRSDRFATTLRNEIQMHRAKLQKSRSTVA 649
QE +P +SP++ + P A P R+ R ++ + KSR +
Sbjct: 1543 QELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVD--------SKSRLSPR 1594
Query: 650 LTAAGEAEDGTGRWRAGLGGGTQEGPLAGTYKDHLKEAQARVLRATSFKRRDLDPNPG-D 708
+ +G + + + RA P A + D E +A RA + R + G
Sbjct: 1595 RSRSGSSPEVKDKPRAA--------PRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRG 1646
Query: 709 LYPESLEHRMGDPDTVPHFWEA--GLAQPPSSTSGGPHPPRIGGRRRFTAEQKLKSYSEP 766
PE P+ P A G P + PPR + S S P
Sbjct: 1647 PSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPR-----------RRSSRSSP 1695
Query: 767 EKMNEVGLTRGYSPHQHPRTSEDTVGTFADRWKFFEETSKPVPQRPAQKQALHGIPRDKP 826
E + L+R + +S +T R + S P P ++ R
Sbjct: 1696 ELTRKARLSRR---SRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRR----RRSA 1748
Query: 827 ERPRTAGRTCEGTEPWSRTTSLGDSLNAHSAAEKAGTSDLPRRLG----TFAEYQASWKE 882
PRT + G P + L S + S EK T+ R G T Q S
Sbjct: 1749 SSPRTKTTSRRGRSPSPKPRGLQRS-RSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSR 1807
Query: 883 QRKPLEARSSGRCHSADDILDVSLDPQERPQHVHGRSRSSPSTDHYKQE----ASVELRR 938
R R HS S R + GRSR+ P++ + A + R
Sbjct: 1808 SRVTRRRRGGSGYHSRSPARQESSRTSSRRRR--GRSRTPPTSRKRSRSRTSPAPWKRSR 1865
Query: 939 QAGDPGEPREELPSAVRAEEGQSTPRQADAQCREGSPGSQQHPPSQKAPNPPTFSELSHC 998
P R +S R + R + ++ P S
Sbjct: 1866 SRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRS 1925
Query: 999 RGAPELPREGRGRAGTLPRDYRYSEESTPADLGPRAQSPGSPLHARGQDSWPVSSALLSK 1058
R P R R R P R S TP R++S P+ R S ++ +++
Sbjct: 1926 RTPPVTRRRSRSRT---PTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRS---RTSPITR 1979
Query: 1059 RPAPQRPPPPKREPRRYRATDGAPADAPVGVLGRPFPTPSPASLDVYVARLSLSHSPSVF 1118
R + R P R R R + PV R SP + R S S +P
Sbjct: 1980 RRSRSRTSPVTRRRSRSRTS-------PV-TRRRSRSRTSPVT-----RRRSRSRTPPAI 2026
Query: 1119 SSAQPQDTPKATVCERGSQHVSGDASRPLPEALLPPKQQHLRLQTATMETSRSPSPQFAP 1178
TP LLP K+ R A SRS +P+ A
Sbjct: 2027 RRRSRSRTP-----------------------LLPRKRSRSRSPLAIRRRSRSRTPRTAR 2063
Query: 1179 QK--LTDKPPLL 1188
K LT PP +
Sbjct: 2064 GKRSLTRSPPAI 2075
Score = 46.2 bits (108), Expect = 3e-04
Identities = 114/540 (21%), Positives = 191/540 (35%), Gaps = 76/540 (14%)
Query: 693 RATSFKRRDLDPNPGDLYPESLEHRMGDPDTVPHFWEAGLAQPPSSTSGGPHPPRIGGRR 752
R+ S ++LD P P+ PD+ +A P S P + +
Sbjct: 1536 RSRSGSSQELDVKPS-ASPQERSESDSSPDS-----KAKTRTPLRQRSRSGSSPEVDSKS 1589
Query: 753 RFTAEQKLKSYSEPEKMNEVGLTRGYSPHQHPRTSEDTVGTFADRWKFFEETSKPVPQRP 812
R + + +S S PE ++ P PR + S P P+ P
Sbjct: 1590 RLSPRRS-RSGSSPEVKDK--------PRAAPRAQSGS-------------DSSPEPKAP 1627
Query: 813 AQKQALHGIPRDKPERPRTAGRTCEGTEPWSRTTSLGDSLNAHSAAEKAGTSDLPRRLGT 872
A PR P R R+ G + +G P +S +S H + R G+
Sbjct: 1628 A--------PRALPRRSRS-GSSSKGRGPSPEGSSSTESSPEHPPKSRTA------RRGS 1672
Query: 873 FAEYQASWKEQRKPLEARSSGRCHSADDILDVSLDPQERPQHVHGRSRSSPSTDHYKQEA 932
+ + K R P RSS S+ ++ R + RSRS+ S+ +
Sbjct: 1673 RSSPEPKTKS-RTPPRRRSS---RSSPELT--------RKARLSRRSRSASSSPETRSRT 1720
Query: 933 SVELRRQAGDPGEPREELPSAVRAEEGQSTPRQADAQCREGSPGSQQHPPSQKAPNP-PT 991
RR + S AE+ +S+ R+ A SP ++ ++P+P P
Sbjct: 1721 PPRHRRSPS--------VSSPEPAEKSRSSRRRRSAS----SPRTKTTSRRGRSPSPKPR 1768
Query: 992 FSELSHCRGAPELPR--EGRGRAGTLPRDYRYSEESTPADLGPRAQSPGSPLHARGQDSW 1049
+ S R E R R R+G+ R + S R + GS H+R
Sbjct: 1769 GLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQ 1828
Query: 1050 PVSSALLSKRPAPQRPPPPKREPRRYRATDGAPADAPVGVLGRPFPTPSPASLDVYVARL 1109
S +R R PP R+ R R T AP S + + R
Sbjct: 1829 ESSRTSSRRRRGRSRTPPTSRKRSRSR-TSPAPWKRSRSRASPATHRRSRSRTPLISRRR 1887
Query: 1110 SLSHSPSVFSSAQPQDTPKATVCERGSQHVSGDASRPLPEALLPP-KQQHLRLQT-ATME 1167
S S + V ++ + + +V R S+ + SR + PP ++ R +T T
Sbjct: 1888 SRSRTSPV---SRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRR 1944
Query: 1168 TSRSPSPQFAPQKLTDKPPLLIQDEDSTRIERVMDNNTTVKMVPIKIVHSESQPEKESRQ 1227
SRS +P ++ + P + + +R + + + P+ S S+ +R+
Sbjct: 1945 RSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRR 2004
Score = 37.0 bits (84), Expect = 0.15
Identities = 85/394 (21%), Positives = 125/394 (31%), Gaps = 40/394 (10%)
Query: 945 EPREELPSAVRAEEGQSTPRQADAQCREGS---PGSQQHPPSQKAPNPPTFSELSHCRGA 1001
+PR AV G TP A GS P + +P S + P P + L R A
Sbjct: 2286 DPRTPTAPAVNLA-GARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSA 2344
Query: 1002 ---PELPREGRGRAGTLPRDYRYSEESTPADLGPRAQSPGSPLHARGQDSWPVSSALLSK 1058
+ G A L S PA G SP PL A + S S LL +
Sbjct: 2345 HATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDR 2404
Query: 1059 ---RPAPQRPPPPKREPRRYRATDGAPADAPVGVLGRPF------PTPSPASLD---VYV 1106
R P P + R + AP L P P PS S +
Sbjct: 2405 ARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIA 2464
Query: 1107 ARLSLSHSPSVFSSAQPQDTPKA-------TVCERGSQH-------VSGDASRPLPEALL 1152
++ S S+ S A T A +V G H S A +P A L
Sbjct: 2465 QTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAAL 2524
Query: 1153 PPKQQHLRLQTATMETSRSPSPQFAPQKLTDKPPLLIQDEDST-------RIERVMDNNT 1205
P ++ +++ +S S S + + E S+ ++RV
Sbjct: 2525 QPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTP 2584
Query: 1206 TVKMVPIKIVHSESQPEKESRQSLACPAEPPALPHGLEKDQIKTLSTSEQFYSRFCLYTR 1265
K + E P K R+S + + + + S+S S +
Sbjct: 2585 APKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2644
Query: 1266 QGAEPEAPHRAQPAEPQPLGTQVPPEKDRCTSPP 1299
+ P A P+P + PP +R + P
Sbjct: 2645 SSSSPSPAKPGPQALPKPASPKKPPPGERRSRSP 2678
>gi|193083191 synaptopodin 2 isoform c [Homo sapiens]
Length = 1109
Score = 59.7 bits (143), Expect = 2e-08
Identities = 33/86 (38%), Positives = 51/86 (59%), Gaps = 2/86 (2%)
Query: 24 GRLVEVQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEIVGINDIGLS 83
G + + ++GGAPWGF L+GG+E +PL + KI SKA+ L GDE+V IN +
Sbjct: 4 GDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASG-SGLCEGDEVVSINGNPCA 62
Query: 84 GFR-QEAICLVKGSHKTLKLVVKRRS 108
E I L++ +L++++KR S
Sbjct: 63 DLTYPEVIKLMESITDSLQMLIKRPS 88
>gi|193083185 synaptopodin 2 isoform b [Homo sapiens]
Length = 1093
Score = 59.7 bits (143), Expect = 2e-08
Identities = 33/86 (38%), Positives = 51/86 (59%), Gaps = 2/86 (2%)
Query: 24 GRLVEVQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEIVGINDIGLS 83
G + + ++GGAPWGF L+GG+E +PL + KI SKA+ L GDE+V IN +
Sbjct: 4 GDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASG-SGLCEGDEVVSINGNPCA 62
Query: 84 GFR-QEAICLVKGSHKTLKLVVKRRS 108
E I L++ +L++++KR S
Sbjct: 63 DLTYPEVIKLMESITDSLQMLIKRPS 88
>gi|193083183 synaptopodin 2 isoform a [Homo sapiens]
Length = 1261
Score = 59.7 bits (143), Expect = 2e-08
Identities = 33/86 (38%), Positives = 51/86 (59%), Gaps = 2/86 (2%)
Query: 24 GRLVEVQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEIVGINDIGLS 83
G + + ++GGAPWGF L+GG+E +PL + KI SKA+ L GDE+V IN +
Sbjct: 4 GDFICISMTGGAPWGFRLQGGKEQKQPLQVAKIRNQSKASG-SGLCEGDEVVSINGNPCA 62
Query: 84 GFR-QEAICLVKGSHKTLKLVVKRRS 108
E I L++ +L++++KR S
Sbjct: 63 DLTYPEVIKLMESITDSLQMLIKRPS 88
>gi|13994151 PDZ and LIM domain 1 [Homo sapiens]
Length = 329
Score = 56.6 bits (135), Expect = 2e-07
Identities = 55/194 (28%), Positives = 84/194 (43%), Gaps = 31/194 (15%)
Query: 28 EVQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEIVGINDIGLSGFRQ 87
++ L G PWGF L GG++ +PL I+++ GSKAA + L GD I I+ S
Sbjct: 5 QIDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALAN-LCIGDVITAIDGENTSNMTH 63
Query: 88 -EAICLVKGSHKTLKLVVKRRSELGWRP--------HSWHATKFSDSHPEL--------A 130
EA +KG L L V R W P H + S+ L +
Sbjct: 64 LEAQNRIKGCTDNLTLTVARSEHKVWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAHNRS 123
Query: 131 ASPFTSTSGCPSWSGRHHASSSSHD----LSSSWEQTNLQRTLDHFSSLGSVDS----LD 182
A PFT++ P+ S ++ ++ L SS +N L+ ++ V++ LD
Sbjct: 124 AMPFTAS---PASSTTARVITNQYNNPAGLYSSENISNFNNALESKTAASGVEANSRPLD 180
Query: 183 H--PSSRLSVAKSN 194
H P S L + K +
Sbjct: 181 HAQPPSSLVIDKES 194
>gi|166235178 PDZ and LIM domain protein 3 isoform b [Homo sapiens]
Length = 316
Score = 56.2 bits (134), Expect = 2e-07
Identities = 36/87 (41%), Positives = 46/87 (52%), Gaps = 2/87 (2%)
Query: 29 VQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEIVGINDIGLSGF-RQ 87
V L G APWGF L GG + +PLVIT+I GSKAAA + L GD I+ I+ G
Sbjct: 5 VILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAAN-LCPGDVILAIDGFGTESMTHA 63
Query: 88 EAICLVKGSHKTLKLVVKRRSELGWRP 114
+A +K + L L + R W P
Sbjct: 64 DAQDRIKAAAHQLCLKIDRGETHLWSP 90
>gi|166235176 PDZ and LIM domain protein 3 isoform a [Homo sapiens]
Length = 364
Score = 56.2 bits (134), Expect = 2e-07
Identities = 36/87 (41%), Positives = 46/87 (52%), Gaps = 2/87 (2%)
Query: 29 VQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEIVGINDIGLSGF-RQ 87
V L G APWGF L GG + +PLVIT+I GSKAAA + L GD I+ I+ G
Sbjct: 5 VILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAAN-LCPGDVILAIDGFGTESMTHA 63
Query: 88 EAICLVKGSHKTLKLVVKRRSELGWRP 114
+A +K + L L + R W P
Sbjct: 64 DAQDRIKAAAHQLCLKIDRGETHLWSP 90
>gi|166706868 synaptopodin 2-like isoform a [Homo sapiens]
Length = 977
Score = 54.7 bits (130), Expect = 7e-07
Identities = 33/86 (38%), Positives = 47/86 (54%), Gaps = 2/86 (2%)
Query: 27 VEVQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEIVGINDIGLSGF- 85
V V LSGGAPWGF L GG E +PL ++KI S+A L D+++ IN + +
Sbjct: 7 VLVTLSGGAPWGFRLHGGAEQRKPLQVSKIRRRSQAGRAG-LRERDQLLAINGVSCTNLS 65
Query: 86 RQEAICLVKGSHKTLKLVVKRRSELG 111
A+ L+ S L L V+R ++ G
Sbjct: 66 HASAMSLIDASGNQLVLTVQRLADEG 91
Score = 35.0 bits (79), Expect = 0.59
Identities = 38/140 (27%), Positives = 49/140 (35%), Gaps = 13/140 (9%)
Query: 937 RRQAGDPGEPREELPSAVRAEEGQSTPRQADAQ--CREGSPGSQQHPPSQKAPNPPTFSE 994
R +A PG E PSA R Q R G+ P ++ N P
Sbjct: 593 RPEAPAPGPGAPEPPSAREQRISVPAARTGILQEARRRGTRKQMFRPGKEETKNSPNPEL 652
Query: 995 LSHCRGAPELPREGRGRAGTLPRDYRYSEESTPADLGPRAQSPGSPLHARGQDSWPVSSA 1054
LS + E PR G +G E LG A + P+ AR + P +
Sbjct: 653 LSLVQNLDEKPRAGGAESG---------PEEDALSLGAEACNFMQPVGARSYKTLPHVTP 703
Query: 1055 LLSKRPAPQRPPP--PKREP 1072
AP+ PPP PK P
Sbjct: 704 KTPPPMAPKTPPPMTPKTPP 723
Score = 31.6 bits (70), Expect = 6.5
Identities = 53/235 (22%), Positives = 80/235 (34%), Gaps = 16/235 (6%)
Query: 955 RAEEGQSTPRQADAQCREGSPGSQQHPPSQKAPNPPTFSELSHCRGAPELPREGRG---- 1010
RA EGQ + Q E S Q Q+ + EL+ A L EG
Sbjct: 367 RASEGQGSG--LGGQLSEVSGRGVQLFEQQRQRADSSTQELARVEPAAMLNGEGLQSPPR 424
Query: 1011 ------RAGTLPRDYRYSEESTPADLGPRAQSPGSPLHARGQDSWPVSSALLSKRPAPQR 1064
A LP + ++P P +P + + P + L +RP
Sbjct: 425 AQSAPPEAAVLPPSPLPAPVASPRPFQPGGGAPTPAPSIFNRSARPFTPGLQGQRPTTTS 484
Query: 1065 PPPPKREPRRYRATDGAPADAPVGVLGRPFPTPSPASLDVYVARLSLSHSPSVFSSAQPQ 1124
P+R + G + AP L PTP P+ + +S SPS S+ P
Sbjct: 485 VIFRPLAPKRANDSLGGLSPAPPPFLSSQGPTPLPSFTSGVPSHAPVSGSPSTPRSSGPV 544
Query: 1125 DTPKATVCERGSQHVSGDASRPLPEALLPPKQQHLRLQTATMETSRSPSPQFAPQ 1179
+ S+ V+ + PE PP + TA++ S P P+
Sbjct: 545 TATSSLYIPAPSRPVTPGGA---PEPPAPPSAAAM-TSTASIFLSAPLRPSARPE 595
>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
Length = 1295
Score = 54.3 bits (129), Expect = 9e-07
Identities = 75/299 (25%), Positives = 103/299 (34%), Gaps = 45/299 (15%)
Query: 956 AEEGQSTPRQADAQCREGSPGSQQHPPSQKAPNPPTFSELSHCRGAPELPREGRGRAGTL 1015
AE + P+ G S P PT SE P P R
Sbjct: 1020 AEVEELLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISE-GPVPSLPIRPSRAPSRTPGP 1078
Query: 1016 PRDYRYSEESTPADLGPRA----QSPGSPLHARGQDSWPVSSALLSKRPAP-QRPPPPK- 1069
P S +S+P D P + P PL + P RPAP QRPPPP
Sbjct: 1079 P-----SAQSSPIDAQPATPLPQKDPAQPLEPKRPP--PPRPVAPPTRPAPPQRPPPPSG 1131
Query: 1070 -REPRRYRATDGAPADAPV---GVLGRPFPTPSPASLDVYVARLSLSHSPSVFSSAQPQD 1125
R P R GAP +GR P+P P+ +S+A+P
Sbjct: 1132 ARSPAPTRKEFGAPKSPGTTRKDNIGRSQPSPQAGLA---------GPGPAGYSTARPTI 1182
Query: 1126 TPKATVCERGSQHVSGDASRPLPEALLPPKQQHLRLQTATMETSRSPSPQFAPQKLTDKP 1185
P+A V H A R PE+ Q+ T ETS+ + F P+ L +
Sbjct: 1183 PPRAGVISAPQSHARASAGRLTPES-----------QSKTSETSKGST--FLPEPLKPQA 1229
Query: 1186 PLLIQDEDSTRIERVMDNNTTV-----KMVPIKIVHSESQPEKESRQSLACPAEPPALP 1239
Q +R+ + V + P + + QP SR S + P+E + P
Sbjct: 1230 AFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQP 1288
>gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens]
Length = 214
Score = 53.9 bits (128), Expect = 1e-06
Identities = 30/81 (37%), Positives = 47/81 (58%), Gaps = 2/81 (2%)
Query: 29 VQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEIVGINDIGLSGFRQ- 87
V L G APWGF L+GG++ PL I+ +++G KAA + + GD ++ I+ I G
Sbjct: 6 VSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQAN-VRIGDVVLSIDGINAQGMTHL 64
Query: 88 EAICLVKGSHKTLKLVVKRRS 108
EA +KG +L + ++R S
Sbjct: 65 EAQNKIKGCTGSLNMTLQRAS 85
>gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens]
Length = 234
Score = 53.9 bits (128), Expect = 1e-06
Identities = 30/81 (37%), Positives = 47/81 (58%), Gaps = 2/81 (2%)
Query: 29 VQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEIVGINDIGLSGFRQ- 87
V L G APWGF L+GG++ PL I+ +++G KAA + + GD ++ I+ I G
Sbjct: 6 VSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQAN-VRIGDVVLSIDGINAQGMTHL 64
Query: 88 EAICLVKGSHKTLKLVVKRRS 108
EA +KG +L + ++R S
Sbjct: 65 EAQNKIKGCTGSLNMTLQRAS 85
>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
Length = 487
Score = 53.9 bits (128), Expect = 1e-06
Identities = 30/81 (37%), Positives = 47/81 (58%), Gaps = 2/81 (2%)
Query: 29 VQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEIVGINDIGLSGFRQ- 87
V L G APWGF L+GG++ PL I+ +++G KAA + + GD ++ I+ I G
Sbjct: 6 VSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQAN-VRIGDVVLSIDGINAQGMTHL 64
Query: 88 EAICLVKGSHKTLKLVVKRRS 108
EA +KG +L + ++R S
Sbjct: 65 EAQNKIKGCTGSLNMTLQRAS 85
>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
Length = 596
Score = 53.9 bits (128), Expect = 1e-06
Identities = 30/81 (37%), Positives = 47/81 (58%), Gaps = 2/81 (2%)
Query: 29 VQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEIVGINDIGLSGFRQ- 87
V L G APWGF L+GG++ PL I+ +++G KAA + + GD ++ I+ I G
Sbjct: 6 VSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQAN-VRIGDVVLSIDGINAQGMTHL 64
Query: 88 EAICLVKGSHKTLKLVVKRRS 108
EA +KG +L + ++R S
Sbjct: 65 EAQNKIKGCTGSLNMTLQRAS 85
>gi|145199237 transcription elongation factor B polypeptide 3 binding
protein 1 [Homo sapiens]
Length = 1221
Score = 53.9 bits (128), Expect = 1e-06
Identities = 109/479 (22%), Positives = 181/479 (37%), Gaps = 62/479 (12%)
Query: 907 DPQERPQHVHGRSRSSPSTDHYKQEASVELRRQA-------GDPGEPREELPSAVRAEEG 959
D ++ V G ++ ST + + ++ Q + G RE +AV+ + G
Sbjct: 288 DSEDEAATVPGNEPTTASTPKARADPEIKATGQPPSKEGLEAEGGGLRETKETAVQCDVG 347
Query: 960 QSTPRQAD----AQCREGSPGS---QQHPPSQKAPNPPTFSELSHCRGAPELPREGRGRA 1012
P A AQ + G + P +K PP S +G + +GRGR
Sbjct: 348 DLQPPPAKPASPAQVQSSQDGGCPKEGKPKKKKTGAPPAPSCKDGAQGKDKTKDKGRGRP 407
Query: 1013 GTLPR-DYRYSEESTPADLGPRAQ------SPGSPL--HARGQDSWPVSSALLSKRPAP- 1062
PR D + + S+P R + S +P+ +G+ P ++RP+P
Sbjct: 408 VEKPRADKKGPQASSPRRKAERPEGTKKKPSSATPVATSGKGRPDRP------ARRPSPT 461
Query: 1063 ---QRPPPPKREPRRYRATDGAPADAPVGVL--GRPFPTPSPASLDV-YVARLSLSHSPS 1116
RP + PR + D AP G L + AS D + + +LSH+
Sbjct: 462 SGDSRPAAGRGPPRPLQLPDRKSTKAPSGKLVERKARSLDEGASQDAPKLKKRALSHADL 521
Query: 1117 VFSSAQ--------PQDTPKATVCERGSQHVSGDASRPLPEALLPPKQQHLRLQTATMET 1168
++ P P A D+S PEA PPK RL+ A+
Sbjct: 522 FGDESEDEAAGPGVPSVWPSALPSLSSDSDSDSDSSLGFPEAQGPPK----RLK-ASPPP 576
Query: 1169 SRSPSPQFAPQKLTDKPPLLIQDEDSTRIERVMDNNTTVKMVPIKIVHSESQPEKESRQS 1228
S +PS + T D D + +E+ +D ++ ++I + + + E R
Sbjct: 577 SPAPSSSSSSSSSTSSAG---ADVDYSALEKEVDFDSDPMEECLRIFNESTSVKTEDRGR 633
Query: 1229 LACPAEPPALPHGLEK--DQIKTLSTSEQFYSRFCLYTRQGAEPEAPHR--AQPAEPQPL 1284
LA +PP EK + TL ++ R ++QG E E P R A P P
Sbjct: 634 LA--RQPPKEEKSEEKGLSGLTTLFPGQK--RRISHLSKQGQEVEPPRRGPAVPPARPPT 689
Query: 1285 GTQVPPEKDRCTSPPGLSYMKAKEKTVEDLKSEELAREIVGKDKSLADILDPSVKIKTT 1343
+V + + S ++A + E KS + G+ + +A I +P + T
Sbjct: 690 AQEVCYLRAQQAQRASASLLQAPARLAE--KSPSVHISAPGEKRRIAHIPNPRLAAAPT 746
>gi|196162711 PDZ and LIM domain 4 isoform 2 [Homo sapiens]
Length = 246
Score = 53.5 bits (127), Expect = 2e-06
Identities = 35/85 (41%), Positives = 42/85 (49%), Gaps = 2/85 (2%)
Query: 29 VQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEIVGINDIGLSGFRQ- 87
V L G +PWGF L GGR+ PL I+++ GSK AA+ L GD I IN
Sbjct: 5 VTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSK-AALAALCPGDLIQAINGESTELMTHL 63
Query: 88 EAICLVKGSHKTLKLVVKRRSELGW 112
EA +KG H L L V R W
Sbjct: 64 EAQNRIKGCHDHLTLSVSRPEGRSW 88
>gi|19923181 PDZ and LIM domain 4 isoform 1 [Homo sapiens]
Length = 330
Score = 53.5 bits (127), Expect = 2e-06
Identities = 35/85 (41%), Positives = 42/85 (49%), Gaps = 2/85 (2%)
Query: 29 VQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEIVGINDIGLSGFRQ- 87
V L G +PWGF L GGR+ PL I+++ GSK AA+ L GD I IN
Sbjct: 5 VTLRGPSPWGFRLVGGRDFSAPLTISRVHAGSK-AALAALCPGDLIQAINGESTELMTHL 63
Query: 88 EAICLVKGSHKTLKLVVKRRSELGW 112
EA +KG H L L V R W
Sbjct: 64 EAQNRIKGCHDHLTLSVSRPEGRSW 88
>gi|4507137 acidic alpha 1 syntrophin [Homo sapiens]
Length = 505
Score = 52.8 bits (125), Expect = 3e-06
Identities = 48/162 (29%), Positives = 78/162 (48%), Gaps = 13/162 (8%)
Query: 4 AEPRARPERLAEAETRAADGGRLVEVQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAA 63
AEP A P +L EA R V V+ + G ++KGGRE+ P++I+KI +G A
Sbjct: 68 AEPGAGPPQLPEALLLQR---RRVTVRKADAGGLGISIKGGRENKMPILISKIFKGLAAD 124
Query: 64 AVDKLLAGDEIVGINDIGL-SGFRQEAICLVKGSHKTLKLVVKRRSELGWRPHSWHATKF 122
+ L GD I+ +N L S EA+ ++K + K + L VK ++ P+ ++T
Sbjct: 125 QTEALFVGDAILSVNGEDLSSATHDEAVQVLKKTGKEVVLEVKYMKDVS--PYFKNSTGG 182
Query: 123 S----DSHPELAASPFTSTSGCPSWSGRHHASSSSHDLSSSW 160
+ DS P ASP P + R+ + + L ++
Sbjct: 183 TSVGWDSPP---ASPLQRQPSSPGPTPRNFSEAKHMSLKMAY 221
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 52.4 bits (124), Expect = 4e-06
Identities = 49/197 (24%), Positives = 77/197 (39%), Gaps = 23/197 (11%)
Query: 912 PQHVHGRSRSSPSTDHYKQEASVELRRQAGDPG-----EPREELPSAVRAEEGQSTPRQA 966
P V R +SP K++ E ++ + R+ LP++ RA ST +
Sbjct: 400 PAPVRRRPEASPVQKKEKKDKERENEKEKSALARERSLKKRQSLPASPRARLSASTASEL 459
Query: 967 D--AQCREGSPGSQQHPPSQKAPNPPTFSELSHCRGAPELPREGRGRAGTLPRDYRYSEE 1024
++ R SP + H P+ P+P L P P RG + R EE
Sbjct: 460 SPKSKARPSSPSTSWHRPASPCPSPGPGHTL------PPKPPSPRGTTASPKGRVRRKEE 513
Query: 1025 S--TPADLGPRAQSPGSPLHARGQDSWPVSSALLSKRPAPQRPPPPKREPRRYRATDGAP 1082
+ +P+ GP +S + ++S +S S P+P PP K +P TD A
Sbjct: 514 AKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAAV 573
Query: 1083 ADAPVGVLGRPFPTPSP 1099
+P P P+P
Sbjct: 574 LTSP--------PAPAP 582
Score = 38.9 bits (89), Expect = 0.041
Identities = 41/197 (20%), Positives = 74/197 (37%), Gaps = 22/197 (11%)
Query: 455 DSPPQVRGLSSCDQ-----KLGSGWQGPRPCVQGDLQAAQLWAGCWPSDTALGALESLPP 509
D+PP ++ +S Q + SG GPRP + + P+ A+G ++ PP
Sbjct: 50 DTPPAMKNATSSKQLPLEPESPSGQVGPRPAPPQEESPSSEAKSRGPTPPAMGPRDARPP 109
Query: 510 PTVGQSPRHHLPQPEGPPDARETGRCYPLDKGAEGCSAGAQEPPRASRAEKASQRLAASI 569
Q +P + PP +E + K A + R E+A A
Sbjct: 110 RRSSQPSPTAVPASDSPPTKQEVKKAGERHKLA-----------KERREERAKYLAAKKA 158
Query: 570 TWADGESSRICPQETPLLHSLTQEGKRRPESSPEDSATRPPPFDAHV-GKPTRRSDRFAT 628
W + E +E L QE +RR E + R + K + +R+
Sbjct: 159 VWLEKEEKAKALREKQL-----QERRRRLEEQRLKAEQRRAALEERQRQKLEKNKERYEA 213
Query: 629 TLRNEIQMHRAKLQKSR 645
++ ++ A++++ R
Sbjct: 214 AIQRSVKKTWAEIRQQR 230
Score = 31.2 bits (69), Expect = 8.5
Identities = 39/136 (28%), Positives = 47/136 (34%), Gaps = 22/136 (16%)
Query: 279 GPRPEYNAEPKLAAPGRSNFGPVWYVPDKKKAPSSPPPP--------PPPLRSDSFAATK 330
GPR E A A R+ P P + PS PPPP PP AT
Sbjct: 4 GPRAELGAGAPPAVVARTPPEPR---PSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATS 60
Query: 331 SH------EKAQGPVFSEAAAAQHFTALAQAQPRGDRRPELTDR----PWRSAHPGSLG- 379
S E G V A Q + ++A+ RG P + R P RS+ P
Sbjct: 61 SKQLPLEPESPSGQVGPRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAV 120
Query: 380 KGSGGPGCPQEAHADG 395
S P QE G
Sbjct: 121 PASDSPPTKQEVKKAG 136
Score = 31.2 bits (69), Expect = 8.5
Identities = 20/68 (29%), Positives = 28/68 (41%), Gaps = 1/68 (1%)
Query: 943 PGEPREELPSAVRAEEGQSTPRQADAQCREGSPGSQQHPPSQKA-PNPPTFSELSHCRGA 1001
P P+EE PS+ G + P R SQ P + A +PPT E+
Sbjct: 79 PAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSPPTKQEVKKAGER 138
Query: 1002 PELPREGR 1009
+L +E R
Sbjct: 139 HKLAKERR 146
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 52.0 bits (123), Expect = 5e-06
Identities = 121/517 (23%), Positives = 167/517 (32%), Gaps = 100/517 (19%)
Query: 859 EKAGTSDLPRRLGTFAEYQASWKEQRKPLEARSSGRCHSADDILDVSLDPQERPQHVHGR 918
E A + R GT + AS R P +SGR A + S P P G
Sbjct: 72 ESAPRAGPTRSAGTSSRNPAS----RPP----ASGRGERAPPAKNTSPGPVSSPGRASGT 123
Query: 919 SRSSP-STDHYKQEASVELRRQAGDPGEPREELPSAVRAEE-----GQSTPRQADAQCRE 972
+R P + A + R R L + R + G +P A
Sbjct: 124 TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA 183
Query: 973 GSPGSQQHPPSQKAPNPPT---------FSELSHCRGAPEL---PREGRGRAGTLPRDYR 1020
G+ P P PPT SE S +P P G G R
Sbjct: 184 GTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 243
Query: 1021 YSEE--STPADLGPRAQ-SPGSPLHARGQDSWPVSSALLSKRPAPQRPPPPKREPRRYRA 1077
S S+PA GP A+ +P +P H S P L + RP PQ PP K
Sbjct: 244 SSATPLSSPARSGPSARGTPRAPAHP----SQPKPKGLQALRP-PQVTPPRK-------- 290
Query: 1078 TDGAPADAPVGVLGRPFPTPSPASLDVYVARLSLSHSPSVFSSAQPQDTPKATVCERGSQ 1137
D APA P+ P TPSP+ + A+P P
Sbjct: 291 -DAAPALGPLS--SSPLATPSPSG-----------------TKARPVPPPD--------- 321
Query: 1138 HVSGDASRPLPEALLPPKQQHLRLQTATMETSRSPSPQFAPQKLTDKPPLLIQDEDSTRI 1197
+A+ PLP L P L A S PS Q P P Q S
Sbjct: 322 ----NAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPS---QAPPSMTT 374
Query: 1198 ERVMDNNTTVKMVPIKIVHSESQPEKESRQSLACPAEPPALPHGLEKDQIKTLSTSEQFY 1257
+ + + PI++ HS + P SL P P AL L+ T + +
Sbjct: 375 PPMQAPPSLQTIPPIQVPHSLTSP------SLQAPPSPLAL-SSLQATTSLGSPTLQATH 427
Query: 1258 SRFCLYTRQG----AEPEAPHRAQPAEP-----------QPLGTQVPPEKDRCTSPPGLS 1302
S + RQ P P P P PL T + P +SP +
Sbjct: 428 SFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIH 487
Query: 1303 YMKAKEKTVEDLKSEELAREIVGKDKSLADILDPSVK 1339
++A L+ I+ ++ + + PS++
Sbjct: 488 PLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQ 524
Score = 48.9 bits (115), Expect = 4e-05
Identities = 115/459 (25%), Positives = 155/459 (33%), Gaps = 76/459 (16%)
Query: 878 ASWKEQRKPLEARSSGRCHSADDILDVSLDPQERPQHVHGRSRSSPSTDHYKQEASVELR 937
AS PL+A S A L SL P P SSP T H Q S
Sbjct: 448 ASTPPDSPPLQAPLS---LPASPPLQTSLSPAVSPL-------SSPLTIHPLQALSSLAS 497
Query: 938 RQAGDPGE----PREELPSAVRAEEGQSTPRQADAQCREGSPGSQQHPPSQKAPNPPTFS 993
P P E S++ Q+ P E P S PP Q A P T
Sbjct: 498 HSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLP-SLAPPPLQTASAPLTTP 556
Query: 994 ELSHCRGAPELPREGRGRAGTLPRDYRYSEESTPADLGPRAQSPGSPLHARGQDSWPVSS 1053
L P + T P S +TP P A + PL +G S P+S
Sbjct: 557 HLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALA-SPPL--QGLPSPPLSP 613
Query: 1054 ALLSKRPAPQRPPPPKREPRRYRATDGAPADAPVGVLGRPFPTPSPASLDVYVARLSLSH 1113
P PQ PP P +A PA P+ L P P +P +L V++ + S
Sbjct: 614 LAT---PPPQAPPXLALPP--LQAPPSPPASPPLSPLATPSPQ-APNALAVHLLQAPFSP 667
Query: 1114 SPSV-----FSS-AQPQDTPKATVCERGSQHV---------SGDASRPLPEALLPPKQQH 1158
PS FS A P +P AT + + S AS P+ + PP Q
Sbjct: 668 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 727
Query: 1159 LRLQTATMETSRSP--SPQFAPQKLTDK--PPLLIQDEDSTRIERVMDNNTTVKMVPIKI 1214
L ++ SP SP +P PPLL P+++
Sbjct: 728 PPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAP-------------------PLQV 768
Query: 1215 VHSESQPEKESRQSLACPAEPPALPHGLEKDQIKTLSTSEQFYSRFCLYTRQGAEPEAPH 1274
S P LA P PP P L ++ L + + ++ + P +P
Sbjct: 769 --PPSPPASLPMSPLAKP--PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 824
Query: 1275 RAQPAEPQPLGT----QVPPEKDRCTSPPGLSYMKAKEK 1309
P + P+ QVPP SPP ++A +
Sbjct: 825 ATPPPQAPPVLAAPLLQVPP------SPPASPTLQAPRR 857
Score = 38.5 bits (88), Expect = 0.053
Identities = 95/383 (24%), Positives = 133/383 (34%), Gaps = 71/383 (18%)
Query: 250 RQAQAAGDPQGSEEKLSCFPPRVPGDSGKGPRPEYNA-------EPKLAAPGRSNFGPVW 302
R+++AAG G PR P + GPR ++ EP AA R + G
Sbjct: 178 RRSRAAGTEVGLPRPAPSARPRPPTE---GPRKSVSSASEHSTTEPSPAARRRPSAGGGL 234
Query: 303 YVPDKKKAPSSPPPPPPPLRSDSFAATKSHEKAQGPVFSEAAAAQHFTALAQAQPRGDR- 361
P + SS P P RS A A +Q +P+G +
Sbjct: 235 QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP---------------SQPKPKGLQA 279
Query: 362 -RPELTDRPWRSAHPGSLGKGSGGP-GCPQEAHADGSWPPSKDGASSRLQASLSSSD--- 416
RP P + A P +LG S P P + P D A++ L A+L S
Sbjct: 280 LRPPQVTPPRKDAAP-ALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLA 338
Query: 417 VRFPQSPHSGRHPP-LYSDHSPLCADSLGQEPGAASFQNDSPPQVRGLSSCDQKLGSGWQ 475
P +P S PP L + SP P + +PP ++ + Q
Sbjct: 339 TPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPI--------Q 390
Query: 476 GPRPCVQGDLQAAQLWAGCWPSDTALGALE---SLPPPTVGQSPRHHLPQPEGPPDARET 532
P LQA PS AL +L+ SL PT+ Q+ L A T
Sbjct: 391 VPHSLTSPSLQAP-------PSPLALSSLQATTSLGSPTL-QATHSFLTMSPRQTQASLT 442
Query: 533 GRCYPLDKGAEGCSAGAQEPP-RASRAEKASQRLAASITWADGESSRICPQETPL----L 587
P S PP +A + AS L S+ S + P +PL L
Sbjct: 443 SPSRP-------ASTPPDSPPLQAPLSLPASPPLQTSL------SPAVSPLSSPLTIHPL 489
Query: 588 HSLTQEGKRRPESSPEDSATRPP 610
+L+ P+ +P S PP
Sbjct: 490 QALSSLASHSPQ-APLSSLIMPP 511
Score = 35.4 bits (80), Expect = 0.45
Identities = 48/191 (25%), Positives = 65/191 (34%), Gaps = 24/191 (12%)
Query: 282 PEYNAEPKLAAPGRSNF-GPVWYVPDKKKAPS-SPPPPPPPLRSDSFAATKSHEKAQGPV 339
P A P L AP R GP V + + +P PPPPP RS S +T S G
Sbjct: 844 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS--STLSGPDLAGHS 901
Query: 340 FSEAAAAQHFTALAQAQPRGDRRPELTDRPWRSAHPGSLGKG-------SGGPGCPQEAH 392
S + + G D + HP + +G G PG P
Sbjct: 902 SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPL--- 958
Query: 393 ADGSWPPSKDGASSRLQASLSSSDVRFPQSPHSGRHPPLYSDHSPLCADSLGQEP--GAA 450
WPP+ S+ ++ + + P S P D P S G+ A
Sbjct: 959 ---PWPPATGPGSADGLCTIYET-----EGPESATPAPGALDPGPSPGTSGGKAAAGAGA 1010
Query: 451 SFQNDSPPQVR 461
+ SP Q R
Sbjct: 1011 GASSRSPKQAR 1021
Score = 35.0 bits (79), Expect = 0.59
Identities = 57/205 (27%), Positives = 76/205 (37%), Gaps = 33/205 (16%)
Query: 248 GGRQAQAAGDPQGSEEKLSCFPPRVPGDSGKG-PR-PEYNAEPKLAAPGRSNFGPVWYVP 305
GG Q A+ S LS P G S +G PR P + ++PK G P P
Sbjct: 232 GGLQRPASRSLSSSATPLSS--PARSGPSARGTPRAPAHPSQPK--PKGLQALRPPQVTP 287
Query: 306 DKKKA-PSSPPPPPPPLRSDSFAATKSH-----EKAQGPVFSEAAAAQHF-TALAQAQPR 358
+K A P+ P PL + S + TK+ + A P+ + + T L A P
Sbjct: 288 PRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPS 347
Query: 359 GDRRPELTDRPWRSAHPGSLGKGSGGPGCPQEAHADGSWPPSKDGASSRLQASLSSSDVR 418
P L P A P P +A + PP +QA S +
Sbjct: 348 PSAPPSLQTLPSPPATP------------PSQAPPSMTTPP--------MQAPPSLQTIP 387
Query: 419 FPQSPHSGRHPPLYSDHSPLCADSL 443
Q PHS P L + SPL SL
Sbjct: 388 PIQVPHSLTSPSLQAPPSPLALSSL 412
Score = 35.0 bits (79), Expect = 0.59
Identities = 78/314 (24%), Positives = 104/314 (33%), Gaps = 77/314 (24%)
Query: 269 PPRVPGDSGKGPRPEYNAEPKLAAPGRSNFGPVWYVPDKKKAPSSPPPPPPPLRSDSFAA 328
PP+ P P + P + PG++ F P +P A +PPP PP+ +
Sbjct: 785 PPQAPPALATPPLQALPSPPA-SFPGQAPFSPSASLPMSPLA--TPPPQAPPVLA----- 836
Query: 329 TKSHEKAQGPVFSEAAAAQHFTALAQAQPRGDRRPELTDRPWRSAHPGSLGKGSG----- 383
L Q P P L P R PG SG
Sbjct: 837 ---------------------APLLQVPPSPPASPTL-QAPRRPPTPGPDTSVSGPRLTL 874
Query: 384 --GPGCPQEAHADGSWPPSKDGASSRLQASLSSSDVRFPQSPHSGRHPPLYSDHSPLCAD 441
PG P PPS+ +S +LS D+ +G S L
Sbjct: 875 ALAPGPPP--------PPSRSPSS-----TLSGPDL-------AGHSSSATSTPEELRGY 914
Query: 442 SLGQEPGAASFQNDSPPQVRGLSSCDQKLGSGWQGPRPCVQGDLQAAQLWAGCWPSDTAL 501
G E GAA+ SPP L++C S +GP P + + A WP T
Sbjct: 915 DSGPEGGAAA----SPPPDAELAACHPAAWS--RGPAPPLA--FRGAPGAPLPWPPATGP 966
Query: 502 GALESLPPPTVGQSPRHHLPQP----EGPPDARETGRCYPLDKGAEGCSAGA--QEPPRA 555
G+ + L + P P P GP G K A G AGA + P +A
Sbjct: 967 GSADGLCTIYETEGPESATPAPGALDPGPSPGTSGG------KAAAGAGAGASSRSPKQA 1020
Query: 556 SRAEKASQRLAASI 569
E L AS+
Sbjct: 1021 RLGELPLGALQASV 1034
Score = 32.0 bits (71), Expect = 5.0
Identities = 88/380 (23%), Positives = 115/380 (30%), Gaps = 39/380 (10%)
Query: 259 QGSEEKLSCFPPRVPGDSGKGPRPEYNAEPKLAAPGRSNFGPVWYVPDKKKAPSSPPPP- 317
Q L+ PP P P A P LA+P P+ +P +P + PPP
Sbjct: 570 QAPPSPLTTPPPETPSSIATPPP---QAPPALASP------PLQGLPSPPLSPLATPPPQ 620
Query: 318 -PPPLRSDSFAATKSHEKAQGPVFSEAA--AAQHFTALAQAQPRGDRRPELTDRPWRSAH 374
PP L A S + P S A + Q ALA + P +
Sbjct: 621 APPXLALPPLQAPPSPPAS--PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 678
Query: 375 PGSLGKGSGGPGCPQEAHADGSWPPSKDGASSRLQASLSSSDVRFPQSPHSGRHPPLYSD 434
P + S P +A + PP + S +S S PQ+P PPL
Sbjct: 679 PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVP 738
Query: 435 HSPLCADSLGQE--------PGAASFQNDSPPQVRGLSSCDQKLGSGWQGPRPCVQGDLQ 486
SP + + P A+ PP Q P LQ
Sbjct: 739 PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQ 798
Query: 487 AAQLWAGCWPSDTALGALESLPPPTVGQSPRHHLPQPEGPPDARETGRCYPLDKGAEGCS 546
A +P SLP + P P+ PP P A
Sbjct: 799 ALPSPPASFPGQAPFSPSASLPMSPLATPP------PQAPPVLAAPLLQVPPSPPASPTL 852
Query: 547 AGAQEPPRASRAEKAS-QRLAASITWADGESSRICPQET---PLL--HSL----TQEGKR 596
+ PP S RL ++ P T P L HS T E R
Sbjct: 853 QAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 912
Query: 597 RPESSPEDSATRPPPFDAHV 616
+S PE A PP DA +
Sbjct: 913 GYDSGPEGGAAASPPPDAEL 932
Score = 31.6 bits (70), Expect = 6.5
Identities = 89/364 (24%), Positives = 111/364 (30%), Gaps = 46/364 (12%)
Query: 269 PPRVPGDSGKGPRPEYNAEPKLAAPGRSNFGPVWYVPDKKKAPSSPPPPPPPLRSDSFAA 328
PP P P P A P P+ VP +PS PP P S A
Sbjct: 360 PPATPPSQAP---PSMTTPPMQAPPSLQTIPPI-QVPHSLTSPSLQAPPSPLALSSLQAT 415
Query: 329 TKSHEKAQGPVFSEAAAAQHFTALAQAQPRGDRRPELT--DRPWRSAHPGSLGKGSGGPG 386
T S + T QA RP T D P A P SL P
Sbjct: 416 TSLGSPTLQATHSFLTMSPRQT---QASLTSPSRPASTPPDSPPLQA-PLSL------PA 465
Query: 387 CP--QEAHADGSWPPSKDGASSRLQASLSSSDVRFPQSPHSGRHPPLYSDHSPLCADSLG 444
P Q + + P S LQA LSS PQ+P S P S L SL
Sbjct: 466 SPPLQTSLSPAVSPLSSPLTIHPLQA-LSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQ 524
Query: 445 QEPGA------ASFQNDSPPQVRGLSSCDQKLGSGWQGPRPC-VQGDLQAAQLWAGCWPS 497
P + + + +PP L + L + PC LQA P
Sbjct: 525 TPPASLTTPPLENLPSLAPPP---LQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPP 581
Query: 498 DTALGALESLP--PPTVGQSPRHHLPQP-----EGPPDARETGRCYPLDKGAEGCSAGAQ 550
+T P PP + P LP P PP P + A
Sbjct: 582 ETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPP 641
Query: 551 EPPRASRAEKASQRLAASITWADGESSRICPQETPLLHSLTQEGKRRPESSPEDSATRPP 610
P A+ + +A LA + A P + P P +SP S + P
Sbjct: 642 LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF----------SPPASPPVSPSATP 691
Query: 611 PFDA 614
P A
Sbjct: 692 PSQA 695
>gi|38327612 PDZ and LIM domain 2 isoform 3 [Homo sapiens]
Length = 278
Score = 52.0 bits (123), Expect = 5e-06
Identities = 31/79 (39%), Positives = 43/79 (54%), Gaps = 2/79 (2%)
Query: 29 VQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEIVGINDIGLSG-FRQ 87
V ++G APWGF + GGR+ P+++TK+ E KA D L GD IV IN G
Sbjct: 5 VDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDAD-LRPGDIIVAINGESAEGMLHA 63
Query: 88 EAICLVKGSHKTLKLVVKR 106
EA ++ S L+L + R
Sbjct: 64 EAQSKIRQSPSPLRLQLDR 82
>gi|28866957 PDZ and LIM domain 2 isoform 1 [Homo sapiens]
Length = 366
Score = 52.0 bits (123), Expect = 5e-06
Identities = 31/79 (39%), Positives = 43/79 (54%), Gaps = 2/79 (2%)
Query: 29 VQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEIVGINDIGLSG-FRQ 87
V ++G APWGF + GGR+ P+++TK+ E KA D L GD IV IN G
Sbjct: 5 VDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDAD-LRPGDIIVAINGESAEGMLHA 63
Query: 88 EAICLVKGSHKTLKLVVKR 106
EA ++ S L+L + R
Sbjct: 64 EAQSKIRQSPSPLRLQLDR 82
Score = 32.3 bits (72), Expect = 3.8
Identities = 59/231 (25%), Positives = 79/231 (34%), Gaps = 24/231 (10%)
Query: 958 EGQSTPRQADAQCREGSPGSQQHPPSQKAPNPPTFSELSHCRGAPELPREGRGRAGTLPR 1017
E QS RQ+ + R SQ P Q N + E+ R +G R T +
Sbjct: 64 EAQSKIRQSPSPLRLQLDRSQATSPGQT--NGDSSLEVLATRF------QGSVRTYTESQ 115
Query: 1018 DYRYSEESTPADLGPRAQSPGSPLHARGQDSWPVSSALLSKRPAPQRPPPPKREPRRYRA 1077
S S+P L PRA SP SP P SS+ L+ A R +
Sbjct: 116 SSLRSSYSSPTSLSPRAGSPFSP---------PPSSSSLTGEAA------ISRSFQSLAC 160
Query: 1078 TDGAPADAPVGVLGRPFPTPSPASLDVYVARLSLSHSPSVFSSAQPQDTPKATVCERGSQ 1137
+ G PA + GRP + A L L SP SS D+ ++
Sbjct: 161 SPGLPAADRLSYSGRPGSRQAGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDEDS 220
Query: 1138 HVSGDASRPLPEALLPPKQQHLR-LQTATMETSRSPSPQFAPQKLTDKPPL 1187
V P + R LQ A R +P F P L+ + L
Sbjct: 221 EVFKMLQENREGRAAPRQSSSFRLLQEALEAEERGGTPAFLPSSLSPQSSL 271
>gi|21361888 PDZ and LIM domain 2 isoform 2 [Homo sapiens]
Length = 352
Score = 52.0 bits (123), Expect = 5e-06
Identities = 31/79 (39%), Positives = 43/79 (54%), Gaps = 2/79 (2%)
Query: 29 VQLSGGAPWGFTLKGGREHGEPLVITKIEEGSKAAAVDKLLAGDEIVGINDIGLSG-FRQ 87
V ++G APWGF + GGR+ P+++TK+ E KA D L GD IV IN G
Sbjct: 5 VDVAGPAPWGFRITGGRDFHTPIMVTKVAERGKAKDAD-LRPGDIIVAINGESAEGMLHA 63
Query: 88 EAICLVKGSHKTLKLVVKR 106
EA ++ S L+L + R
Sbjct: 64 EAQSKIRQSPSPLRLQLDR 82
Score = 32.3 bits (72), Expect = 3.8
Identities = 59/231 (25%), Positives = 79/231 (34%), Gaps = 24/231 (10%)
Query: 958 EGQSTPRQADAQCREGSPGSQQHPPSQKAPNPPTFSELSHCRGAPELPREGRGRAGTLPR 1017
E QS RQ+ + R SQ P Q N + E+ R +G R T +
Sbjct: 64 EAQSKIRQSPSPLRLQLDRSQATSPGQT--NGDSSLEVLATRF------QGSVRTYTESQ 115
Query: 1018 DYRYSEESTPADLGPRAQSPGSPLHARGQDSWPVSSALLSKRPAPQRPPPPKREPRRYRA 1077
S S+P L PRA SP SP P SS+ L+ A R +
Sbjct: 116 SSLRSSYSSPTSLSPRAGSPFSP---------PPSSSSLTGEAA------ISRSFQSLAC 160
Query: 1078 TDGAPADAPVGVLGRPFPTPSPASLDVYVARLSLSHSPSVFSSAQPQDTPKATVCERGSQ 1137
+ G PA + GRP + A L L SP SS D+ ++
Sbjct: 161 SPGLPAADRLSYSGRPGSRQAGLGRAGDSAVLVLPPSPGPRSSRPSMDSEGGSLLLDEDS 220
Query: 1138 HVSGDASRPLPEALLPPKQQHLR-LQTATMETSRSPSPQFAPQKLTDKPPL 1187
V P + R LQ A R +P F P L+ + L
Sbjct: 221 EVFKMLQENREGRAAPRQSSSFRLLQEALEAEERGGTPAFLPSSLSPQSSL 271
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 51.6 bits (122), Expect = 6e-06
Identities = 97/409 (23%), Positives = 142/409 (34%), Gaps = 61/409 (14%)
Query: 905 SLDPQERPQHVHGRSRSSPSTDHYKQEASVELRRQAGDPGEPREELPSAVRAEEGQSTPR 964
S DP++ Q S S PS + ++ ++Q P + P+ V + P
Sbjct: 144 SSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPG 203
Query: 965 -----------QADAQCREGSPGSQQHPPSQKAPNPPTFSELSHCRGAPEL--PREGRGR 1011
A A +GSP + Q P +AP P +H + AP L R
Sbjct: 204 TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPV--PHTHIQQAPALHPQRPPSPH 261
Query: 1012 AGTLPRDYRYSEESTPADLGPRAQSPGSP-LHARGQDSWPVSSALLSKRPAPQRPPPPKR 1070
P + + T + P A S P LH +G P L P Q P PP+
Sbjct: 262 PPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQG----PPGPHSLQAGPLLQHPGPPQP 317
Query: 1071 EPRRYRATDGAPADAPVGVLGRPFPTPSPASLDVYVARLSLSHSPSVFSSAQPQDTPKAT 1130
+A+ G AP+G SPA+ + + L L S S S QP
Sbjct: 318 FGLPPQASQG---QAPLGT--------SPAAAYPHTS-LQLPASQSALQSQQPPREQPLP 365
Query: 1131 VCERGSQHVSGDASRPLPEALLPPKQQHLRLQTATMETSRSPSPQFAPQKLTDKPPLLIQ 1190
H+ + P+P+ LP Q H + PSP L P L
Sbjct: 366 PAPLAMPHIKPPPTTPIPQ--LPAPQAHKHPPHLS-----GPSPFSMNANLPPPPALKPL 418
Query: 1191 DEDSTRIERVMDNNTTVKMVPIKIVHSESQPEKESRQSLACPAEPPALPHGLEKDQIKTL 1250
ST + + P++++ +SQP S PA+PP L Q + L
Sbjct: 419 SSLSTH------HPPSAHPPPLQLM-PQSQPLPSS------PAQPPGL------TQSQNL 459
Query: 1251 STSEQFYSRFCLYTRQGAEPEAPHRAQPAEPQPLGTQVPPEKDRCTSPP 1299
+ L+ P A H P P P+ PP ++PP
Sbjct: 460 PPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPI---TPPTCPSTSTPP 505
Score = 43.9 bits (102), Expect = 0.001
Identities = 121/549 (22%), Positives = 180/549 (32%), Gaps = 94/549 (17%)
Query: 167 RTLDHFSSLGSVDSLDHPSSRLSVAKSNSSIDHLGSHSKRDSAYGSFSTSSS--TPDHTL 224
RT + + + PS + + S++ GS +D + STS S +P
Sbjct: 109 RTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNE 168
Query: 225 SKADTSSAENILYTVGLWEAPRQGGRQAQAAGDPQGSEEKLSCFPPRVPGDSGKGPRPEY 284
S +D+S+ + +L Q A P G S PP P GP P
Sbjct: 169 SDSDSSAQQQMLQA------------QPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSA 216
Query: 285 NAEPKLAAPGRSNFGPVWYVPDKKKAPSSPPP--------------PPPPLRSDSFAATK 330
A P +P S P++ +AP++P P PP P
Sbjct: 217 TAVPPQGSPTASQ------APNQPQAPTAPVPHTHIQQAPALHPQRPPSP-------HPP 263
Query: 331 SHEKAQGPVFSEAAAAQHFTALAQAQP----RGDRRPELTDRPWRSAHPGSLGKGSGGPG 386
H P+ +A +A + AQP +G P HPG + G P
Sbjct: 264 PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP-PQPFGLPP 322
Query: 387 CPQEAHADGSWPPSKDGASSRLQASLSSSDVRFPQSPHSGRHP--PLYSDH-SPLCADSL 443
+ A P+ + LQ S S ++ Q P P PL H P +
Sbjct: 323 QASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPI 382
Query: 444 GQEP------------GAASFQNDS----PPQVRGLSSCDQKLGSGWQGPRPCVQGDLQA 487
Q P G + F ++ PP ++ LSS P + Q
Sbjct: 383 PQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQP 442
Query: 488 AQLWAGCWPSDTA----LGALESLPPPTVGQSPR--HHL-PQPEGPPDARETGRCYPLDK 540
PS A L ++LPPP P H + PQP G P+
Sbjct: 443 L-------PSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITP 495
Query: 541 GAEGCSAGAQEPPRASRAEKASQRLAASITWADGESSRICPQETPLLHSLTQEGKRRPES 600
++ P S S A+ + A G S CP T + + PES
Sbjct: 496 PTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSS---CPLPTVQIKEEALDDAEEPES 552
Query: 601 --------SPEDSATRPPPFDAHVGKPTRRSDR-FATTLRNEI---QMHRAKLQKSRSTV 648
SPE + P + + + DR + + R ++ + +KL K R
Sbjct: 553 PPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEA 612
Query: 649 ALTAAGEAE 657
A EAE
Sbjct: 613 IEKAKREAE 621
Score = 37.0 bits (84), Expect = 0.15
Identities = 102/511 (19%), Positives = 161/511 (31%), Gaps = 125/511 (24%)
Query: 913 QHVHGRSRSSPST-DHYKQEASVELRRQAGDPGEPREELPSAVRAEEGQSTPRQADAQCR 971
+ + R+SPS ++ E +++ + +EE S +++ + Q +D +
Sbjct: 50 EDIRSSGRNSPSAASTSSNDSKAETVKKSAK--KVKEEASSPLKSNKRQREKVASDTEEA 107
Query: 972 EGSPGSQQHPPSQKAPNPPTFSELSHCRGAPELPREGRGRAGTLPRDYRYSEESTPADLG 1031
+ + + PN P+ E + + EG + +D R + S P+
Sbjct: 108 DRTSSKKTKTQEISRPNSPSEGE-GESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQD 166
Query: 1032 PRAQSPGSPLHARGQDSWPVSSALLSKRPAPQRPPPPKREPRRYRATDGAPADAPVGVLG 1091
+ S S Q P A PAP PP G P L
Sbjct: 167 NESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPP------------GTPQ------LP 208
Query: 1092 RPFPTPSPASLDVYVARLSLSHSPSVFSSAQPQDTPKATVCERGSQHVSGDASRPLPEAL 1151
P PTPS ++ PQ +P A+ Q P A
Sbjct: 209 TPGPTPSA-------------------TAVPPQGSPTASQAPNQPQ---------APTAP 240
Query: 1152 LPPKQQHLRLQTA-TMETSRSPSPQFAPQKLTDKPPLLIQDEDSTRIERVMDNNTTVKMV 1210
+P H +Q A + R PSP P + PPL
Sbjct: 241 VP----HTHIQQAPALHPQRPPSPH-PPPHPSPHPPLQ---------------------- 273
Query: 1211 PIKIVHSESQPEKESRQSLACPAEPPALPHGLEKDQIKTLSTSEQFYSRFCLYTRQGAEP 1270
+ S QP S + P PH L+ A P
Sbjct: 274 --PLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQ------------------------AGP 307
Query: 1271 EAPHRAQPAEPQPLGTQVPPEKDRCTSPPGLSYMKAKEKTVEDLKSEELAREIVGKDKSL 1330
H P PQP G +PP+ + +P G S A T L + + A + +
Sbjct: 308 LLQH---PGPPQPFG--LPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQ 362
Query: 1331 ----ADILDPSVKIKTTMDLMEGIFPKDEHLLEEAQQRRKLLPKIPSPRSTEERKEEPSV 1386
A + P +K T + + A Q K P + P P
Sbjct: 363 PLPPAPLAMPHIKPPPTTPIPQ----------LPAPQAHKHPPHLSGPSPFSMNANLPPP 412
Query: 1387 PAAVSLATNSTYYSTSA--PKAELLIKMKDL 1415
PA L++ ST++ SA P +L+ + + L
Sbjct: 413 PALKPLSSLSTHHPPSAHPPPLQLMPQSQPL 443
Score = 31.6 bits (70), Expect = 6.5
Identities = 47/183 (25%), Positives = 63/183 (34%), Gaps = 34/183 (18%)
Query: 910 ERPQHVHGRSRSS-----PSTDHYKQEASVELRRQAGDPGEPREELPSAVRAEEGQSTPR 964
+ P H+ G S S P K +S+ P + +P +++ S+P
Sbjct: 392 KHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMP---QSQPLPSSPA 448
Query: 965 QADA--QCREGSPGSQQHPPS---QKAPNPPTFSELSHCRGAPELPREGRGRAGTLPRDY 1019
Q Q + P HPP+ Q AP PP G P + T P
Sbjct: 449 QPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPP------TCP--- 499
Query: 1020 RYSEESTPADLGPRAQSPGSPLHARGQD-----SWP-----VSSALLSKRPAPQRPPPPK 1069
S + PA G AQ P S A G S P + L P+ PPPP
Sbjct: 500 --STSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPP 557
Query: 1070 REP 1072
R P
Sbjct: 558 RSP 560
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.129 0.383
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 78,625,062
Number of Sequences: 37866
Number of extensions: 4744634
Number of successful extensions: 30022
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 120
Number of HSP's successfully gapped in prelim test: 1147
Number of HSP's that attempted gapping in prelim test: 22613
Number of HSP's gapped (non-prelim): 7590
length of query: 1616
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1500
effective length of database: 13,855,062
effective search space: 20782593000
effective search space used: 20782593000
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.