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Search of human proteins with 31442420
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31442420 shroom family member 1 [Homo sapiens]
(847 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31442420 shroom family member 1 [Homo sapiens] 1718 0.0
gi|4502175 apical protein of Xenopus-like [Homo sapiens] 117 3e-26
gi|203098098 shroom family member 3 protein [Homo sapiens] 110 5e-24
gi|118600967 shroom family member 4 [Homo sapiens] 108 2e-23
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 59 2e-08
gi|88196790 coiled-coil domain containing 88 [Homo sapiens] 57 6e-08
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 54 8e-07
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 50 7e-06
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 50 9e-06
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 50 1e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni... 50 1e-05
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 49 2e-05
gi|31324577 molecule interacting with Rab13 [Homo sapiens] 49 2e-05
gi|24797153 faciogenital dysplasia protein [Homo sapiens] 49 3e-05
gi|150170670 piccolo isoform 2 [Homo sapiens] 49 3e-05
gi|150378539 piccolo isoform 1 [Homo sapiens] 49 3e-05
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 48 3e-05
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 48 3e-05
gi|122937241 SH3 and multiple ankyrin repeat domains 3 [Homo sap... 47 6e-05
gi|7662236 TSC22 domain family, member 2 [Homo sapiens] 47 6e-05
gi|38683860 insulin receptor substrate 2 [Homo sapiens] 47 1e-04
gi|24308326 BR serine/threonine kinase 1 [Homo sapiens] 46 1e-04
gi|16262452 cingulin [Homo sapiens] 45 2e-04
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 45 3e-04
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 44 5e-04
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 44 6e-04
gi|110832843 TBP-associated factor 4 [Homo sapiens] 44 8e-04
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 44 8e-04
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 44 8e-04
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 43 0.001
>gi|31442420 shroom family member 1 [Homo sapiens]
Length = 847
Score = 1718 bits (4450), Expect = 0.0
Identities = 847/847 (100%), Positives = 847/847 (100%)
Query: 1 MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDW 60
MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDW
Sbjct: 1 MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDW 60
Query: 61 DYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAA 120
DYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAA
Sbjct: 61 DYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAA 120
Query: 121 EAEAAAQAVEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPP 180
EAEAAAQAVEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPP
Sbjct: 121 EAEAAAQAVEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPP 180
Query: 181 ATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPAR 240
ATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPAR
Sbjct: 181 ATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPAR 240
Query: 241 ECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRP 300
ECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRP
Sbjct: 241 ECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRP 300
Query: 301 ASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAEL 360
ASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAEL
Sbjct: 301 ASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAEL 360
Query: 361 PQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQ 420
PQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQ
Sbjct: 361 PQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQ 420
Query: 421 PYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIP 480
PYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIP
Sbjct: 421 PYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIP 480
Query: 481 TIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQ 540
TIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQ
Sbjct: 481 TIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQ 540
Query: 541 CLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIPLAEVRAAMRPACGEAGEEAAST 600
CLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIPLAEVRAAMRPACGEAGEEAAST
Sbjct: 541 CLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIPLAEVRAAMRPACGEAGEEAAST 600
Query: 601 FEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQGKKVELAARLQK 660
FEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQGKKVELAARLQK
Sbjct: 601 FEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQGKKVELAARLQK 660
Query: 661 MLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMADLERVLGLLLLLG 720
MLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMADLERVLGLLLLLG
Sbjct: 661 MLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMADLERVLGLLLLLG 720
Query: 721 SRLARVRRALARAASDSDPDEQRLRLLQRQEEDAKELKEHVARRERAVREVLVRALPVEE 780
SRLARVRRALARAASDSDPDEQRLRLLQRQEEDAKELKEHVARRERAVREVLVRALPVEE
Sbjct: 721 SRLARVRRALARAASDSDPDEQRLRLLQRQEEDAKELKEHVARRERAVREVLVRALPVEE 780
Query: 781 LRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDLGHHAPSPSPARPPGTCPPVQP 840
LRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDLGHHAPSPSPARPPGTCPPVQP
Sbjct: 781 LRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDLGHHAPSPSPARPPGTCPPVQP 840
Query: 841 PFPLLLT 847
PFPLLLT
Sbjct: 841 PFPLLLT 847
>gi|4502175 apical protein of Xenopus-like [Homo sapiens]
Length = 1616
Score = 117 bits (294), Expect = 3e-26
Identities = 94/301 (31%), Positives = 150/301 (49%), Gaps = 31/301 (10%)
Query: 543 EELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIPL-------AEVRAAMRP------A 589
EEL +E+ D SL D L + + L++G+ P A+ R + P +
Sbjct: 1317 EELAREIVGKDKSLADILDPSVKIKTTMDLMEGIFPKDEHLLEEAQQRRKLLPKIPSPRS 1376
Query: 590 CGEAGEE----AASTFEPGSYQFSFTQLLPAPREET--RLENPATHPVLDQPCGQGLPAP 643
E EE AA + S +S + AP+ E ++++ ++ G L
Sbjct: 1377 TEERKEEPSVPAAVSLATNSTYYSTS----APKAELLIKMKDLQEQQEHEEDSGSDL--- 1429
Query: 644 NNSIQGKKVELAARLQKMLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQELERFS 703
++ + KK EL + + LQ L +E L + QA A +EA V+ C P E ++F
Sbjct: 1430 DHDLSVKKQELIESISRKLQVLREARESLLEDVQANTVLGAEVEAIVKGVCKPSEFDKFR 1489
Query: 704 RFMADLERVLGLLLLLGSRLARVRRALARAASDSDPDE-----QRLRLLQRQEEDAKELK 758
F+ DL++V+ LLL L RLARV AL + P + ++ R+L +Q EDAKELK
Sbjct: 1490 MFIGDLDKVVNLLLSLSGRLARVENALNNLDDGASPGDRQSLLEKQRVLIQQHEDAKELK 1549
Query: 759 EHVARRERAVREVLVRALPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDD 818
E++ RRER V ++L L E L Y + K+A++ +QR L+++I L ++QL + D
Sbjct: 1550 ENLDRRERIVFDILANYLSEESLADYEHFVKMKSALIIEQRELEDKIHLGEEQLKCLLDS 1609
Query: 819 L 819
L
Sbjct: 1610 L 1610
Score = 50.8 bits (120), Expect = 5e-06
Identities = 110/477 (23%), Positives = 164/477 (34%), Gaps = 100/477 (20%)
Query: 1 MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDW 60
+++L R S A S SS+D + DSAY SFS +S P+ T +
Sbjct: 178 VDSLDHPSSRLSVAKSNSSIDHLGSHSKRDSAYGSFSTSSSTPDHTLSKADTSSAENI-- 235
Query: 61 DYVRVVWGGPGPAPPDAALCTSPR----------PRPAVAARSGPQP--TEVPGTPGPLN 108
Y +W P A P+ PR + GP+P P P
Sbjct: 236 LYTVGLWEAPRQGGRQAQAAGDPQGSEEKLSCFPPRVPGDSGKGPRPEYNAEPKLAAPGR 295
Query: 109 RQATPLLYALAAEAEAAAQAVEPPSPP--ASRAAYRQRLQGAQRRVLRETSFQRKELRMS 166
P+ Y + + A + PP PP + A + + AQ V E + + +
Sbjct: 296 SNFGPVWY--VPDKKKAPSSPPPPPPPLRSDSFAATKSHEKAQGPVFSEAAAAQ---HFT 350
Query: 167 LPARLRPTVPARPPATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEP 226
A+ +P RP T R +HPG G+ G G A+ W S+
Sbjct: 351 ALAQAQPRGDRRPELT-DRPWRSAHPGSLGK-------GSGGPGCPQEAHADGSWPPSKD 402
Query: 227 GKLDRVGRGGGPARECLGEACSSSGLPGPE-PLEFQHPALAKFEDHEVGWLPETQPQGSM 285
G R L + SSS + P+ P +HP L + DH S+
Sbjct: 403 GASSR-----------LQASLSSSDVRFPQSPHSGRHPPL--YSDH------SPLCADSL 443
Query: 286 NLDSGSLKLGDAFRPASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAE------------ 333
+ G+ + P R S+ + LGS G G P VQ Q A+
Sbjct: 444 GQEPGAASFQNDSPPQVRGLSSCDQKLGS--GWQGPRPCVQGDLQAAQLWAGCWPSDTAL 501
Query: 334 -----TPRPLFQTKLSRFLPQ-------KEAAVMYP------------AELPQSSPAD-S 368
P P LPQ +E YP E P++S A+ +
Sbjct: 502 GALESLPPPTVGQSPRHHLPQPEGPPDARETGRCYPLDKGAEGCSAGAQEPPRASRAEKA 561
Query: 369 EQRVSETCIVPAWLPSLPDEVFLEEAPLV---------RMRSPPDPHASQGPPASVH 416
QR++ + W + +E PL+ R S P+ A++ PP H
Sbjct: 562 SQRLAASI---TWADGESSRICPQETPLLHSLTQEGKRRPESSPEDSATRPPPFDAH 615
Score = 39.3 bits (90), Expect = 0.016
Identities = 34/105 (32%), Positives = 48/105 (45%), Gaps = 11/105 (10%)
Query: 141 YRQRLQGAQRRVLRETSFQRKELRMS----LPARLRPTVPARPPATHPRSASLSHPGGEG 196
Y+ L+ AQ RVLR TSF+R++L + P L + H A L+ P
Sbjct: 680 YKDHLKEAQARVLRATSFKRRDLDPNPGDLYPESLEHRMGDPDTVPHFWEAGLAQP---- 735
Query: 197 EPARSRAP-APGTAGRGPLANQQRKWCFSEPGKLDRVG--RGGGP 238
+ S P P GR +Q+ +SEP K++ VG RG P
Sbjct: 736 PSSTSGGPHPPRIGGRRRFTAEQKLKSYSEPEKMNEVGLTRGYSP 780
>gi|203098098 shroom family member 3 protein [Homo sapiens]
Length = 1996
Score = 110 bits (275), Expect = 5e-24
Identities = 163/698 (23%), Positives = 259/698 (37%), Gaps = 104/698 (14%)
Query: 174 TVPARPPAT--HPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDR 231
+VP+ P T H R AS R P P R PLA Q + L
Sbjct: 1311 SVPSECPGTLDHQRQAS-------------RTPCP----RPPLAGTQGLVTDTRAAPLTP 1353
Query: 232 VGRGGGPARECLGEA-CSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSG 290
+G P + CS G G +PL PA+ H TQP G +
Sbjct: 1354 IGT---PLPSAIPSGYCSQDGQTGRQPLPPYTPAMM----HRSNGHTLTQPPGPRGCEGD 1406
Query: 291 SLKLG-----------DAFRPASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLF 339
+ G + P SR++ A ++P + P A
Sbjct: 1407 GPEHGVEEGTRKRVSLPQWPPPSRAKWAHA-------AREDSLPEESSAPDFANLKHYQK 1459
Query: 340 QTKLSRFLPQKEAAVMYPAELPQSSPADSEQRVSETCIVPAWLP--SLPDEVFLEE---- 393
Q L + P P S+P R+SE+ + + P DEVF+ +
Sbjct: 1460 QQSLPSLCSTSDPDT--PLGAP-STPGRISLRISESVLRDSPPPHEDYEDEVFVRDPHPK 1516
Query: 394 ---APLVR-MRSPPDPHASQG---------PPASVHA-------SDQPYGTGLG-QRTGQ 432
+P + PP P SQ PP H S+ P G + +
Sbjct: 1517 ATSSPTFEPLPPPPPPPPSQETPVYSMDDFPPPPPHTVCEAQLDSEDPEGPRPSFNKLSK 1576
Query: 433 VTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIPTIDPTGLTTNPP 492
VT+ E PG A VG S T + P+ ++ +
Sbjct: 1577 VTIARE---RHMPGAAHV----------VGSQTLASRLQTSIKGSEAESTPPSFMSVHAQ 1623
Query: 493 TAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQCLEELVQELARL 552
A +P P LS + G T P + + E L +E+
Sbjct: 1624 LAGSLGG-QPAPIQTQSLSHDPVSG----TQGLEKKVSPDPQKSSEDIRTEALAKEIVHQ 1678
Query: 553 DPSLCDPLASQPSPEPPLGLLDGLIP----LAEVRAAMRPACGEAGEEAASTFEPGSYQF 608
D SL D L + + L++GL P L + + R A + + +
Sbjct: 1679 DKSLADILDPDSRLKTTMDLMEGLFPRDVNLLKENSVKRKAIQRTVSSSGCEGKRNEDKE 1738
Query: 609 SFTQLL--PAPREETRLENPATHPVLDQPCGQGLPAPNNSIQGKKVELAARLQKMLQDLH 666
+ + L+ PA + + + + + P + KK EL L L+ L
Sbjct: 1739 AVSMLVNCPAYYSVSAPKAELLNKIKEMPAEVNEEEEQADVNEKKAELIGSLTHKLETLQ 1798
Query: 667 TEQERLQGEAQAWARRQAALEAAVRQACAPQELERFSRFMADLERVLGLLLLLGSRLARV 726
+ L + + +EA + + C P E +++ F+ DL++V+ LLL L RLARV
Sbjct: 1799 EAKGSLLTDIKLNNALGEEVEALISELCKPNEFDKYRMFIGDLDKVVNLLLSLSGRLARV 1858
Query: 727 RRALARAASDSDPDE-----QRLRLLQRQEEDAKELKEHVARRERAVREVLVRALPVEEL 781
L+ D+ +E ++ ++L Q EDA+ELKE++ RRER V +L L E+L
Sbjct: 1859 ENVLSGLGEDASNEERSSLYEKRKILAGQHEDARELKENLDRRERVVLGILANYLSEEQL 1918
Query: 782 RVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAIRDDL 819
+ Y + K+ +L +QR LD++I+L Q+Q+ + + L
Sbjct: 1919 QDYQHFVKMKSTLLIEQRKLDDKIKLGQEQVKCLLESL 1956
Score = 77.4 bits (189), Expect = 5e-14
Identities = 147/593 (24%), Positives = 214/593 (36%), Gaps = 164/593 (27%)
Query: 69 GPGPAPPDAALCTSPRP-RPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAAEAEAAAQ 127
G GP PDA L S + + P+ + PG+P +PLL A
Sbjct: 875 GRGPQRPDARLLRSQSTFQLSSEPEREPEWRDRPGSP------ESPLLDA---------- 918
Query: 128 AVEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPPATH---- 183
P SRA YR ++ AQ RVL TSF+R++L + P R P RP + H
Sbjct: 919 -------PFSRA-YRNSIKDAQSRVLGATSFRRRDLELGAPVASRSWRP-RPSSAHVGLR 969
Query: 184 -PRSASLSHP----------GGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRV 232
P +++ + P EG+ AR PA R L +Q+K +SEP K++ V
Sbjct: 970 SPEASASASPHTPRERHSVTPAEGDLARPVPPAARRGARRRLTPEQKKRSYSEPEKMNEV 1029
Query: 233 G-------RGGGPARECL-----------------GEACSSSGLPGPEPLEFQHPALAKF 268
G GP R + G+ACS+ L GPE +FQ ALA +
Sbjct: 1030 GIVEEAEPAPLGPQRNGMRFPESSVADRRRLFERDGKACSTLSLSGPELKQFQQSALADY 1089
Query: 269 EDHEVGWLPETQPQGSM--------NLDSGSLKLGDA----------------------- 297
+ G P + S+ S L+ G A
Sbjct: 1090 IQRKTGKRPTSAAGCSLQEPGPLRERAQSAYLQPGPAALEGSGLASASSLSSLREPSLQP 1149
Query: 298 -------------FRPASRSRSAS---GEVLGS-------WGGSGGTIPIVQAVPQGAET 334
+ A R RS+S G LG G +GGT + +G ET
Sbjct: 1150 RREATLLPATVAETQQAPRDRSSSFAGGRRLGERRRGDLLSGANGGT----RGTQRGDET 1205
Query: 335 PRP-------LFQTKLSRFLPQKEAAVMYPAEL-PQSSPADSEQRVSETCIVPAWLPSLP 386
PR ++ + L ++ + P + +SSPA +++R + +
Sbjct: 1206 PREPSSWGARAGKSMSAEDLLERSDVLAGPVHVRSRSSPATADKRQDVLLGQDSGFGLVK 1265
Query: 387 DEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQPYGTGLGQRTGQVTVPTEYPLHECPG 446
D +L P R S + + P H + + G+G + G +VP+ ECPG
Sbjct: 1266 DPCYL-AGPGSRSLSCSERGQEEMLPLFHHLTPRWGGSGC-KAIGDSSVPS-----ECPG 1318
Query: 447 T------AGADDC----WQGVNGSVGISRPTSHTPTGTANDNIPTIDPTGLTTNPPTAAE 496
T A C G G V +R TP GT +P+ P+G +
Sbjct: 1319 TLDHQRQASRTPCPRPPLAGTQGLVTDTRAAPLTPIGTP---LPSAIPSGYCSQDGQTGR 1375
Query: 497 SDLLKPVPA-----------DALGLSGNDTPGPSHNTALARGTGQPGSRPTWP 538
L PA G G + GP H + GT + S P WP
Sbjct: 1376 QPLPPYTPAMMHRSNGHTLTQPPGPRGCEGDGPEH--GVEEGTRKRVSLPQWP 1426
Score = 38.9 bits (89), Expect = 0.020
Identities = 67/271 (24%), Positives = 100/271 (36%), Gaps = 59/271 (21%)
Query: 1 MEALGPGGD----RASPASSTSSLD-LWHLSMRADSAYSSFSAASG-------GPEPRTQ 48
ME+L P G SPA ST S+D L H + DSAYSSFS +S G R +
Sbjct: 223 MESLEPSGAYPPCHLSPAKSTGSIDQLSHFHNKRDSAYSSFSTSSSILEYPHPGISGRER 282
Query: 49 SPGTDL----------LPYLDWDYVRVVW------GGPGPAPPDAALCTSPRPRPAVAAR 92
S D + D YV+ V+ A L R + +
Sbjct: 283 SGSMDNTSARGGLLEGMRQADIRYVKTVYDTRRGVSAEYEVNSSALLLQGREARASANGQ 342
Query: 93 SGPQPTEVP---GTPGPLNRQATPLLYALAAEAEAAAQAVEPPSPPA---SRAAYRQRLQ 146
+ + +P G P P Q P +L + V P PPA S AA+R R +
Sbjct: 343 GYDKWSNIPRGKGVPPPSWSQQCP--SSLETATDNLPPKVGAPLPPARSDSYAAFRHRER 400
Query: 147 GA------QRRVLR---------ETSFQRKELRMSLPARLRPTVPARPPATHPRSA---- 187
+ Q+R+ R ++ F ++L L + P +P + + A
Sbjct: 401 PSSWSSLDQKRLCRPQANSLGSLKSPFIEEQLHTVLEKSPENSPPVKPKHNYTQKAQPGQ 460
Query: 188 ----SLSHPGGEGEPARSRAPAPGTAGRGPL 214
+ +P EP ++ P P + G L
Sbjct: 461 PLLPTSIYPVPSLEPHFAQVPQPSVSSNGML 491
>gi|118600967 shroom family member 4 [Homo sapiens]
Length = 1493
Score = 108 bits (270), Expect = 2e-23
Identities = 67/197 (34%), Positives = 115/197 (58%), Gaps = 12/197 (6%)
Query: 633 DQP----CGQGLPAPNNSIQGKKVELAARLQKMLQDLHTEQERLQGEAQAWARRQAALEA 688
DQP G G ++ + KK++L + + L L Q L + A + +EA
Sbjct: 1292 DQPEMAEIGLGEEEVDHELAQKKIQLIESISRKLSVLREAQRGLLEDINANSALGEEVEA 1351
Query: 689 AVRQACAPQELERFSRFMADLERVLGLLLLLGSRLARVRRALARAASDSDPDEQRLRLLQ 748
++ C E E++ F+ DL++V+ LLL L RLARV AL + DS+ ++++L L++
Sbjct: 1352 NLKAVCKSNEFEKYHLFVGDLDKVVNLLLSLSGRLARVENALN--SIDSEANQEKLVLIE 1409
Query: 749 RQEE------DAKELKEHVARRERAVREVLVRALPVEELRVYCALLAGKAAVLAQQRNLD 802
++++ DAKELKEHV RRE+ V ++ R LP ++L+ Y + K+A++ +QR L+
Sbjct: 1410 KKQQLTGQLADAKELKEHVDRREKLVFGMVSRYLPQDQLQDYQHFVKMKSALIIEQRELE 1469
Query: 803 ERIRLLQDQLDAIRDDL 819
E+I+L ++QL +R+ L
Sbjct: 1470 EKIKLGEEQLKCLRESL 1486
Score = 42.0 bits (97), Expect = 0.002
Identities = 68/265 (25%), Positives = 95/265 (35%), Gaps = 43/265 (16%)
Query: 1 MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPE----PRTQSPGTDLLP 56
ME+L G +A+ S +D + DSAYSSFSA+S + R + P +
Sbjct: 159 MESLEQPG-QATYESHLLPIDQNMYPNQRDSAYSSFSASSNASDCALSLRPEEPAS---- 213
Query: 57 YLDWDYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLY 116
+ GPGP +P RP VA SG G P ++ ++
Sbjct: 214 ------TDCIMQGPGPT-------KAPSGRPNVAETSGGSRRTNGGHLTPSSQMSSRPQE 260
Query: 117 ALAAEAEAAAQAVEPPSPPASR----AAYRQRLQGAQRRVLRETSFQRKELRMSLPARLR 172
+ A + PP PP R A+ Q L G QRR ++ ++S L
Sbjct: 261 GYQSGPAKAVRG--PPQPPVRRDSLQASRAQLLNGEQRRASEPVVPLPQKEKLS----LE 314
Query: 173 PTVPARPP------ATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEP 226
P +PAR P + H + S H E S+ P G L Q P
Sbjct: 315 PVLPARNPNRFCCLSGHDQVTSEGHQNCE----FSQPPESSQQGSEHLLMQASTKAVGSP 370
Query: 227 GKLDRVGR-GGGPARECLGEACSSS 250
DR P E E +S
Sbjct: 371 KACDRASSVDSNPLNEASAELAKAS 395
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 58.5 bits (140), Expect = 2e-08
Identities = 128/555 (23%), Positives = 176/555 (31%), Gaps = 85/555 (15%)
Query: 70 PGPAPPDAALCTSPRPRPAVAARSGPQPT----EVPGTPGPLNRQATPLLYALAAEAEAA 125
P P PP + L PRP + P PT P L R L+++ + E A+
Sbjct: 1329 PAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSAS 1388
Query: 126 AQAVEP---------PSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVP 176
A P PS A+ + + +S L SLP + T+P
Sbjct: 1389 APGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLP 1448
Query: 177 ARPPATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGG 236
A P SA L+ P + PA T+ PLA + PG G
Sbjct: 1449 A------PASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVP----AAPGPPSLAPSGA 1498
Query: 237 GPARECL------GEACSSSGLPGPEPLEFQHP-ALAKFEDHEVGWLPETQPQGSMNLDS 289
P+ L + SSS PG HP LA H G P S L
Sbjct: 1499 SPSASALTLGLATAPSLSSSQTPG-------HPLLLAPTSSHVPGLNSTVAPACSPVLVP 1551
Query: 290 GSLKLGDAFRPASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQ 349
S L F A A +L + Q TP + L
Sbjct: 1552 AS-ALASPFPSAPNPAPAQASLLAP----------ASSASQALATPLAPMAAPQTAILAP 1600
Query: 350 KEAAVMYPAELPQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQ 409
A + P + SP + S VP PS L A V P P
Sbjct: 1601 SPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPV-----PAPTPVL 1655
Query: 410 GPPASVHASDQPYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSH 469
P ++ P VP+ P P + + ++G S P+
Sbjct: 1656 APSSTQTMLPAP-------------VPSPLP---SPASTQTLALAPALAPTLGGSSPSQT 1699
Query: 470 TPTGTANDNIPTIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTG 529
GT N P PT + P ++ L P PA L L+ GP+ +LA
Sbjct: 1700 LSLGTGNPQGPF--PTQTLSLTPASS----LVPTPAQTLSLAPGPPLGPTQTLSLAPAPP 1753
Query: 530 QPGSRPTWPSQC----LEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIPLAEVRAA 585
+ P P+ L + L P+ L P+P P LG P A A
Sbjct: 1754 LAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSPAPVPTLG------PAAAQTLA 1807
Query: 586 MRPACGEAGEEAAST 600
+ PA ++ AS+
Sbjct: 1808 LAPASTQSPASQASS 1822
Score = 31.6 bits (70), Expect = 3.2
Identities = 86/364 (23%), Positives = 122/364 (33%), Gaps = 61/364 (16%)
Query: 70 PGPAPPDAALCTSP---RPRPAVAARSGPQPTEVPGTPG-PLNRQATPLLYALAAEAEAA 125
P PP A CT P P PA P + G P P++ T L L EAE
Sbjct: 2497 PACTPPPA--CTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELC 2554
Query: 126 AQAVEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPPATH-- 183
AQA+ P + S + L + P L P P +
Sbjct: 2555 AQALASPE---------------SLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKN 2599
Query: 184 ----PRSASLSHPGG---EGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGG 236
P + SL+ G G+ + A GT ++ C SE L+
Sbjct: 2600 LSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAA 2659
Query: 237 G--PARECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKL 294
P +E L EA +S E E + P + + E+ P S + S
Sbjct: 2660 SDEPLQEPL-EADRTS----EELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGP 2714
Query: 295 GDAFRPASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAV 354
A RP R SA E+ G G G + P P K+ R LP + V
Sbjct: 2715 SPA-RPPRRRTSADVEIRGQGTGRPG------------QPPGP----KVLRKLPGRLVTV 2757
Query: 355 MYPAELPQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPAS 414
+ EL + +QR + + +V P + + +P VR S P+ G P
Sbjct: 2758 VEEKELVRRR---RQQRGAASTLV----PGVSETSASPGSPSVRSMSGPESSPPIGGPCE 2810
Query: 415 VHAS 418
S
Sbjct: 2811 AAPS 2814
>gi|88196790 coiled-coil domain containing 88 [Homo sapiens]
Length = 1476
Score = 57.4 bits (137), Expect = 6e-08
Identities = 162/690 (23%), Positives = 236/690 (34%), Gaps = 149/690 (21%)
Query: 136 ASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPPATHPRSASLSHPGG- 194
AS+A ++L+ A+ R R QR+ L + R H SL H
Sbjct: 365 ASKALLEEQLEAARERCARLHETQRENLLLR----------TRLGEAHAELDSLRHQVDQ 414
Query: 195 --------EGEPARSRAPAPGTAGRGPLANQ----QRKWCFSEPGKLDRVGRGGGPAREC 242
E E RS P PG+ G PLA Q + +E G+L + R RE
Sbjct: 415 LAEENVELELELQRSLEPPPGSPGEAPLAGAAPSLQDEVREAEAGRLRTLEREN---REL 471
Query: 243 LGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRPAS 302
G G PG QHP L + V + E PQ P +
Sbjct: 472 RGLLQVLQGQPGG-----QHPLLEAPREDPVLPVLEEAPQ----------------TPVA 510
Query: 303 RSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAELPQ 362
S G V + G PQ + P + L EA+ P + P
Sbjct: 511 FDHSPQGLVQKARDGG----------PQALDLAPPALDSVL-------EASAECP-QAPD 552
Query: 363 SSPADSEQRVSETCIVPAWLPSLPDE----VFLEEAP-----LVRMRSPPDPHASQGPPA 413
S P ++E + + P P E V +E+P ++SP QGP
Sbjct: 553 SDPQEAESPLQAAAMDPQASDWSPQESGSPVETQESPEKAGRRSSLQSPASVAPPQGPGT 612
Query: 414 SVHASDQPYGTGLGQRTGQ-VTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPT 472
+ A G G+ Q VP + L + +G G S P+S
Sbjct: 613 KIQAPQLLGGETEGREAPQGELVPEAWGLRQ-----------EGPEHKPGPSEPSSVQLE 661
Query: 473 GTANDNIPTIDPTGLTTNPPTAAESDLL-----------KPVPADALGLSGNDTPGPSHN 521
N L T A E D KP L GP
Sbjct: 662 EQEGPN----QGLDLATGQAEAREHDQRLEGTVRDPAWQKPQQKSEGALEVQVWEGPIPG 717
Query: 522 TALARGTGQPGSRPTWPSQCLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIP--L 579
+LA G + + L E V +L R +L D L +Q + L
Sbjct: 718 ESLASGVAE--------QEALREEVAQLRRKAEALGDELEAQARKLEAQNTEAARLSKEL 769
Query: 580 AEVRAAMRPACGEAGEEAASTFEPGSYQFSFTQLLPAPREETRLENPATHPVLDQPCGQG 639
A+ R A A EA +A E+ RL + GQ
Sbjct: 770 AQARRAEAEAHREAEAQAW--------------------EQARLREAV------EAAGQE 803
Query: 640 LPAPNNSIQGKKVELAARLQKMLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQEL 699
L + + + LAA ++ Q E RL+ +++A R LE+ RQ E
Sbjct: 804 LESASQEREALVEALAAAGRERRQ-WEREGSRLRAQSEAAEERMQVLESEGRQHLEEAER 862
Query: 700 ERFSR--FMADLERVLGLLLLLGSRLARVRRALARAA-------SDSDPDEQRLRLLQRQ 750
ER + A+LE+ + LG+RL ++R L +AA + + QR + L+++
Sbjct: 863 ERREKEALQAELEKAVVRGKELGARLEHLQRELEQAALERQEFLREKESQHQRYQGLEQR 922
Query: 751 EEDAKELKEHVARRERAVREVLVRALPVEE 780
E EL+ +E A+ E+ RAL +EE
Sbjct: 923 LE--AELQAAATSKEEALMELKTRALQLEE 950
Score = 32.0 bits (71), Expect = 2.5
Identities = 42/159 (26%), Positives = 64/159 (40%), Gaps = 39/159 (24%)
Query: 640 LPAPNNSIQGKKVELAARLQKMLQDLHTEQERLQGEAQAWARRQAALEAAVRQACAPQEL 699
L A S++ ++V L A ++++QD H RQ LE +R+ E
Sbjct: 1123 LQAQRASVEAQEVALLAERERLMQDGH---------------RQRGLEEELRRL--QSEH 1165
Query: 700 ERFSRFMADLERVLGLLL----LLGSRLARVRRALARAASDSDP---DEQRL-------- 744
+R +A+L R G L L RLAR+ A+ S Q+L
Sbjct: 1166 DRAQMLLAELSRERGELQGERGELRGRLARLELERAQLEMQSQQLRESNQQLDLSACRLT 1225
Query: 745 -------RLLQRQEEDAKELKEHVARRERAVREVLVRAL 776
+L QEE+ ++L V R RE+L R+L
Sbjct: 1226 TQCELLTQLRSAQEEENRQLLAEVQALSRENRELLERSL 1264
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 53.5 bits (127), Expect = 8e-07
Identities = 191/871 (21%), Positives = 257/871 (29%), Gaps = 189/871 (21%)
Query: 67 WGGP--GPAPPDAA----LCTSPRPRPAVAARSGPQ-----PTEVPGTPGPLNRQATPLL 115
WG G APP+ P P PA A + P P PG PGP
Sbjct: 290 WGPERKGSAPPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPG-PGPRPP------ 342
Query: 116 YALAAEAEAAAQAVEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSL-PARLR-- 172
AE+ A PP LRE+ QR + S+ PA
Sbjct: 343 ---GAESHGCLPATRPPGSD-----------------LRESRVQRSRMDSSVSPAATTAC 382
Query: 173 -PTVPARPPATHPRSASLSHPGGEGEPARSRAPAPGTAGR----------------GPLA 215
P P+RPP + S S R P PG G GP A
Sbjct: 383 VPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSA 442
Query: 216 NQQRKWCFSEPGKLDRVGRGGGPARECLGEACSSSGLPGPEPLEFQHPAL-AKFEDHEV- 273
+ RK P + GP+ C P P P + PA A ED E+
Sbjct: 443 HSSRKPFLGAPAATPHLSLPPGPSSPP-PPPCPRLLRPPPPPAWLKGPACRAAREDGEIL 501
Query: 274 -------------GWLPETQPQGSMNLDSGSLKLGDAFR-----PASRSRSASGEVLGSW 315
P +G + + +G P + + S+S GS
Sbjct: 502 EELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSH 561
Query: 316 GGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAELPQSSPADSEQRVSET 375
S P A + PL + PQ V LP + P+ Q S +
Sbjct: 562 SSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGS 621
Query: 376 CIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQG-PPASVHASDQPYGTGLGQRTGQVT 434
P E+P R+ P P G PP + + QP G+G+
Sbjct: 622 FRRP-------------ESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGE------ 662
Query: 435 VPTEYP-LHECPGTAGADDCWQGVNGSV---GISRPTSHTPTGTANDNIPTIDPTGLTTN 490
+P P L + P T D + + G++ + G+
Sbjct: 663 LPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQ 722
Query: 491 PPTAAE-SDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQCLEELVQEL 549
PP + L P P D + + T T P L L
Sbjct: 723 PPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPP-PPPL 781
Query: 550 ARLDPSLCDPLASQPSPEPPLGLLDGLIPLAEVRAAMRPACGEAGEEAASTFEPGSYQFS 609
A+ P P QP P PP L LA V + G AA + PG
Sbjct: 782 AKFPP----PSQPQPPPPPPPSPASLLKSLASVLEGQKYC--YRGTGAAVSTRPG--PLP 833
Query: 610 FTQLLPAPREETRLENPATHPVLDQPCGQGLPAPNNSIQGKKVELAARLQKMLQDLHTEQ 669
TQ P P A P P QG P P+ S
Sbjct: 834 TTQYSPGPPSGA----TALPPTSAAPSAQGSPQPSAS---------------------SS 868
Query: 670 ERLQGEAQAWARRQAALEAAVRQACAPQE---------LERFSRFMADLERVLGLLLLLG 720
+ WAR + A E V P + S + ++ R L+
Sbjct: 869 SQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERV 928
Query: 721 SRLARVRRALARAASDSDPDEQRL------------------RLLQRQEEDAKELKEH-- 760
R A A +D +RL +RQ+E KE + H
Sbjct: 929 GRSATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKRRQKEHQKEHRRHRR 988
Query: 761 -----VARRERAVREVLVRALPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAI 815
V RR R R +P E+ R VL NLD + +Q + +
Sbjct: 989 ACKDSVGRRPREGRAKAKAKVPKEKSR----------RVLG---NLDLQSEEIQGR-EKS 1034
Query: 816 RDDLGHHA---PSPSPARPPGTCPPVQPPFP 843
R DLG + P +PA P P QP P
Sbjct: 1035 RPDLGGASKAKPPTAPAPPSAPAPSAQPTPP 1065
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 50.4 bits (119), Expect = 7e-06
Identities = 49/146 (33%), Positives = 53/146 (36%), Gaps = 41/146 (28%)
Query: 68 GGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAAEAEAAAQ 127
G PAPP A PR PA AA + P PT P P A P A AAA
Sbjct: 105 GATPPAPPRA-----PRGAPAAAAAAAPPPTPAPPPPPAPVAAAAP----ARAPRAAAAA 155
Query: 128 AVEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPPATHPRSA 187
A PPSP ++ R AQR + P P PA PPA P
Sbjct: 156 ATAPPSPGPAQPGPR-----AQR---------------AAPLAAPPPAPAAPPAVAP--- 192
Query: 188 SLSHPGGEGEPARSRAPAPGTAGRGP 213
P G RAP P A R P
Sbjct: 193 ----PAGP-----RRAPPPAVAAREP 209
Score = 38.1 bits (87), Expect = 0.035
Identities = 75/304 (24%), Positives = 107/304 (35%), Gaps = 52/304 (17%)
Query: 89 VAARSGPQPTEVPGTPGPLNRQATPLL--------YALAAEAEAAAQAVEPPSPPASRAA 140
V R GP+P L +Q L Y AA + + PP+PP +
Sbjct: 58 VRRRHGPEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAP-- 115
Query: 141 YRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPPATHPRSASLSHPGGEGEPAR 200
+GA + A P PA PP P +A+ A
Sbjct: 116 -----RGAPA---------------AAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAA 155
Query: 201 SRAP-APGTAGRGPLANQQRKWCFSEPGKL--DRVGRGGGPARECLGEACSSSGLPGPEP 257
+ AP +PG A GP A + P V GP R A ++ P P P
Sbjct: 156 ATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGP-RRAPPPAVAAREPPLPPP 214
Query: 258 LEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRPASRSRSASGEVLGSWGG 317
Q PA + + P QPQ + G+++ G A RP S LG GG
Sbjct: 215 P--QPPAPPQQQQP-----PPPQPQPPP--EGGAVRAGGAARPVSLREVV--RYLGGSGG 263
Query: 318 SGGTIP---IVQAVPQGAETPRPLFQTKLSRF-LPQKEAAVMYP---AELPQSSPADSEQ 370
+GG + + + + A L +T+L LP+ + P + P S E+
Sbjct: 264 AGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPRGDRPGRAPPAASARPSRSKRGGEE 323
Query: 371 RVSE 374
RV E
Sbjct: 324 RVLE 327
Score = 35.0 bits (79), Expect = 0.29
Identities = 43/142 (30%), Positives = 52/142 (36%), Gaps = 17/142 (11%)
Query: 70 PGPA-PPDAALCTSPR--PRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAAEAEAAA 126
P PA PP A PR P PAVAAR P P P P P +Q P A
Sbjct: 182 PAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPP-PQPPAPPQQQQPPPPQPQPPPEGGAV 240
Query: 127 QAVEPPSPPASRAAYR----------QRLQGAQRRVLRETSFQRKEL---RMSLPARLRP 173
+A P + R R + +G + +L E + R L R+ A R
Sbjct: 241 RAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPRG 300
Query: 174 TVPARPPATHPRSASLSHPGGE 195
P R P S S GGE
Sbjct: 301 DRPGRAPPAASARPSRSKRGGE 322
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 50.1 bits (118), Expect = 9e-06
Identities = 147/630 (23%), Positives = 205/630 (32%), Gaps = 135/630 (21%)
Query: 72 PAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAAEAEAAAQAVEP 131
P PP SPRP P V P V G G + R+ LA A A P
Sbjct: 27 PRPPG-----SPRPPPPVT----PAALRVLGAAGAVGRKP------LAERAGGIGGATIP 71
Query: 132 PSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPPATHPRSASLSH 191
S P + R R + R E + PA+ P P R++ +
Sbjct: 72 ESAP----------RAGPTRTSRPPASGRGE--RAPPAKNTSPGPVSSPG---RASGTTR 116
Query: 192 PGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPARECLGE----AC 247
PG G+ R A T RG ++ S + D G G + A
Sbjct: 117 PGPLGQKGL-RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 175
Query: 248 SSSGLPGPEPLEFQHP-------ALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRP 300
+ GLP P P P +++ +H E P +G G RP
Sbjct: 176 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHST---TEPSPAARRRPSAG----GGLQRP 228
Query: 301 ASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAEL 360
ASRS S+S L S SG + P P+P K + P
Sbjct: 229 ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKP------------KGLQALRP--- 273
Query: 361 PQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGP--PASVHAS 418
PQ +P + PA P L +PL + P P A P P S+
Sbjct: 274 PQVTPPRKD-------AAPALGP-------LSSSPL----ATPSPSAPPSPSAPPSLQTL 315
Query: 419 DQPYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDN 478
P T Q T + PT H + ++ P P A
Sbjct: 316 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP----------LATPPPQAPPALA--- 362
Query: 479 IPTIDPTGLTTNPPTAAE-SDLLKPVP--ADALGLSGNDTP-GPSHNTALARGTGQPGSR 534
+ P +PP + S L P P +AL + P P + + P S
Sbjct: 363 ---LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 419
Query: 535 P-----TWPSQCLEELVQELARLDPS--LCDPL--ASQPSPEPPLGLLDGLIPLAEVRAA 585
P T PSQ L ++ PS P+ ++ P P+ P L + LA+
Sbjct: 420 PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ 479
Query: 586 MRPACG----EAGEEAASTFEPGSYQFSFTQLLP----------------APREETRLEN 625
PA +A ++F PG FS + LP AP +
Sbjct: 480 APPALATPPLQALPSPPASF-PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 538
Query: 626 PATHPVLDQPCGQGLPAPNNSIQGKKVELA 655
PA+ P L P P P+ S+ G ++ LA
Sbjct: 539 PAS-PTLQAPRRPPTPGPDTSVSGPRLTLA 567
Score = 35.4 bits (80), Expect = 0.22
Identities = 45/155 (29%), Positives = 59/155 (38%), Gaps = 18/155 (11%)
Query: 70 PGPAPPDAALCTSP-RPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAAEAEAAAQA 128
P +PP + T P + P++AA P P +P P++ ATP A A Q
Sbjct: 415 PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP-PMSPSATPPPQAPPPLAAPPLQL 473
Query: 129 VEPP--SPPASRAAYRQRLQGAQRRVLRETSFQ-RKELRMS---LPARLRPTVPARP--- 179
+PP +PPA Q L + F L MS P P V A P
Sbjct: 474 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 533
Query: 180 -PATHPRSASLSHPGGEGEPARSRAPAPGTAGRGP 213
P + P S +L P R P P T+ GP
Sbjct: 534 VPPSPPASPTLQ------APRRPPTPGPDTSVSGP 562
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 49.7 bits (117), Expect = 1e-05
Identities = 125/527 (23%), Positives = 180/527 (34%), Gaps = 91/527 (17%)
Query: 133 SPPASRAAYRQRLQGAQRRVLRETS----FQRKELRMSLPARLRPTVPARPPATHPRSAS 188
+PPA R R R R+ R S +R R AR + ++ PPA RSAS
Sbjct: 2022 TPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSAS 2081
Query: 189 LSHPGGEGEPARSRAPAPGTAGRG-----PLA-NQQRKWCFSEPGK----LDRVGRGG-- 236
G + +RS P P T P+A N R CFS P LDR G
Sbjct: 2082 ----GSSSDRSRSATP-PATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGML 2136
Query: 237 ---GPARECLG--EACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGS 291
G +R + + S + GP P + DH+ +PE Q + L +
Sbjct: 2137 EPLGSSRTPMSVLQQAGGSMMDGPGP---------RIPDHQRTSVPENHAQSRIALALTA 2187
Query: 292 LKLGDAFRPASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKE 351
+ LG A P S S + G + VP P PL + +
Sbjct: 2188 ISLGTARPPPSMS-------------AAGLAARMSQVP----APVPLMSLRTA------- 2223
Query: 352 AAVMYPAELPQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSP--------- 402
A + +P +S A + T +P + +L D A + + SP
Sbjct: 2224 PAANLASRIPAASAAAMNLASARTPAIPTAV-NLADSRTPAAAAAMNLASPRTAVAPSAV 2282
Query: 403 --PDPHASQGPPASVHASDQPYGTGLGQRTGQVTVPT--EYPLHECPGTAGADDCWQGVN 458
DP P ++ + P TG T PT YP A A G
Sbjct: 2283 NLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPR 2342
Query: 459 GSVGISRPTSHTPTGTANDNIPTIDPTGLTT--NPPTAAESDLLKP-VPADALGLSGNDT 515
S + P + + TA + P LT+ P + ++L P VP A T
Sbjct: 2343 -SAHATAPVNIAGSRTA----AALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRT 2397
Query: 516 PGPSHNTALARGTGQPGSRPTWPSQCLEELVQELARL----DPSLCDPLASQP-SPEPPL 570
P + A +R P S P+ E +R+ SL P QP SP P
Sbjct: 2398 SPPLLDRARSR---TPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSA 2454
Query: 571 GLLDGLIPLAEVRAAMRPACGEAGEEAASTFEPGSYQFSFTQLLPAP 617
+A+ +G A +T G + + +PAP
Sbjct: 2455 FSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLS--VPAP 2499
Score = 40.0 bits (92), Expect = 0.009
Identities = 49/208 (23%), Positives = 82/208 (39%), Gaps = 35/208 (16%)
Query: 1 MEALGPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDW 60
+ AL P +R S +SS+SS S + S+ SS S++S + S G+ L
Sbjct: 2521 LAALQPAKERRSSSSSSSS------SSSSSSSSSSSSSSSSSGSSSSDSEGSSL------ 2568
Query: 61 DYVRVVWGGPGPAPPDAAL--CTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYAL 118
P P+ AL SP P P A R G P TP R+++ +
Sbjct: 2569 -----------PVQPEVALKRVPSPTPAPKEAVREGRPPEP---TPAKRKRRSS----SS 2610
Query: 119 AAEAEAAAQAVEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPAR 178
++ + +++ + S +S ++ + + K +LP +P P +
Sbjct: 2611 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALP---KPASPKK 2667
Query: 179 PPATHPRSASLSHPGGEGEPARSRAPAP 206
PP RS S P +RS + +P
Sbjct: 2668 PPPGERRSRSPRKPIDSLRDSRSLSYSP 2695
Score = 35.4 bits (80), Expect = 0.22
Identities = 41/169 (24%), Positives = 63/169 (37%), Gaps = 24/169 (14%)
Query: 84 RPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAAEAEAAAQAVE--------PPSPP 135
+PR A A+SG + P P P +A P + ++ + E P PP
Sbjct: 1607 KPRAAPRAQSGSDSSPEPKAPAP---RALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPP 1663
Query: 136 ASRAAYRQRLQGAQRRVLRETSFQRKELRMS--------LPARLR-----PTVPARPPAT 182
SR A R + + T +R+ R S L R R P +R P
Sbjct: 1664 KSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPR 1723
Query: 183 HPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDR 231
H RS S+S P + SR ++ R +++ + +P L R
Sbjct: 1724 HRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQR 1772
Score = 32.7 bits (73), Expect = 1.5
Identities = 47/203 (23%), Positives = 81/203 (39%), Gaps = 14/203 (6%)
Query: 401 SPPDPHASQGPPASVHASDQPY---GTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGV 457
SPP S+ P H+S P+ +G R G +T P +E T C++
Sbjct: 820 SPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSP---QANEQSVTPQRRSCFESS 876
Query: 458 NGSVGISR-PTSHTPTGTANDNIPTIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTP 516
SR P+ H+ +G++ + + P + + ++ + + + SG+ +P
Sbjct: 877 PDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSP 936
Query: 517 GPSHNTALARGTGQPGSRPTWPSQCLEELVQELARLDPSLCDPLASQPSPE-PPLGLLDG 575
PS T+ T SR P +E + L R S ++ PE PP G
Sbjct: 937 SPSRVTS---RTTPRRSRSVSPCSNVESRL--LPRYSHSGSSSPDTKVKPETPPRQSHSG 991
Query: 576 LI-PLAEVRAAMRPACGEAGEEA 597
I P +V+A P +G ++
Sbjct: 992 SISPYPKVKAQTPPGPSLSGSKS 1014
Score = 30.4 bits (67), Expect = 7.2
Identities = 36/123 (29%), Positives = 48/123 (39%), Gaps = 10/123 (8%)
Query: 90 AARSGPQPTEVPGTPGPLNRQATPLLYALAAEAEAAAQAVEPPSPPASRAAYR------- 142
+AR G + P T G +R TP + A + +P R+ R
Sbjct: 556 SARRGRSHSRSPATRGR-SRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGR 614
Query: 143 QRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPPATHPRSASLSHPGGEGEPARSR 202
R + RR R S R+ R PAR +R PA RS S + P G +RSR
Sbjct: 615 SRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRT-PARRGR-SRSR 672
Query: 203 APA 205
PA
Sbjct: 673 TPA 675
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 49.7 bits (117), Expect = 1e-05
Identities = 143/602 (23%), Positives = 189/602 (31%), Gaps = 80/602 (13%)
Query: 68 GGPG-PAP-----PDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAAE 121
GGP P+P P AA SP+ A G T P P ATP +
Sbjct: 1092 GGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATP-----PPK 1146
Query: 122 AEAAAQAVEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPPA 181
A PPSP A + GA + L P + PT PA P
Sbjct: 1147 GAPTTPAATPPSPKGGLATPPPK--GAPTTPAATPPSPKGGLATPSP-KGAPTTPAATPP 1203
Query: 182 THPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPARE 241
+ L+ P +G P A P + +G LA K + P +GG
Sbjct: 1204 S--PKGGLATPSPKGAPTTPAATPP--SPKGGLATPSPKGAPTTPAATPPSPKGGPATPP 1259
Query: 242 CLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMN---LDSGSLKLGDAF 298
G P P P+L G L +G+ N + S K G A
Sbjct: 1260 PKG---------APTPPAATPPSLK-------GGLATPPHKGAPNPAVVTPPSPKGGPAT 1303
Query: 299 RPASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPA 358
P + + S GS GT P P+GA TP + P + PA
Sbjct: 1304 SPPKGAPTPPAATPPSPKGSPGTPP-----PKGAPTPPAVTP-------PSPKGTPTLPA 1351
Query: 359 ELPQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHAS 418
P S + E PA PS + P + +PP P P+
Sbjct: 1352 TTPSSKGGPTTPSSKEGPTPPAATPS------HKGGPAM---TPPSPKRGPAIPSPKGDP 1402
Query: 419 DQPYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISR-PTSHTPTGTAND 477
P L + T T E T D V + + P + P G
Sbjct: 1403 TSPAVIPLSPKKAPATPVT----REGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPAT 1458
Query: 478 NIPTIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTAL-ARGTGQPGSRPT 536
DPT PP+ E K V + TP P L A P P
Sbjct: 1459 PSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPA 1518
Query: 537 WPSQCLEELVQELARLDPSLCDPLASQPSPEPPLGLLDG-----LIPLAEVRAAMRPACG 591
PS + + L LA + + PP + IP + A P+
Sbjct: 1519 TPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPK-EAPATPSSK 1577
Query: 592 EAGEEAASTFEPGSYQF--SFTQLL--PAPREETRLENPATHPVLDQPC---GQGLPAPN 644
EA A T P +Y+ S +LL PA + E P T P + P G PAP
Sbjct: 1578 EASSPPAVT--PSTYKGAPSPKELLIPPAVTSPSPKEAP-TPPAVTPPSPEKGPATPAPK 1634
Query: 645 NS 646
+
Sbjct: 1635 GT 1636
Score = 48.5 bits (114), Expect = 3e-05
Identities = 136/618 (22%), Positives = 186/618 (30%), Gaps = 96/618 (15%)
Query: 6 PGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSP----GTDLLPYLDWD 61
P +A S TSS + A + + G P P +P G P W
Sbjct: 903 PAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKW- 961
Query: 62 YVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAAE 121
P+P SP+ P A + P P P TP P P + + +
Sbjct: 962 -APTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPK 1020
Query: 122 AEAAA----------QAVEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARL 171
AA A PPSP S AA L T K + +
Sbjct: 1021 GSPAATPFPKGASTPPAATPPSPKGSPAA--TPLPKGAPTTPAATLPSPKGGPATPSLKG 1078
Query: 172 RPTVPARPPATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDR 231
PT PA P + + P G P + P+P +G LA K + P
Sbjct: 1079 APTPPAATPPSPKGGPATPSPKGAPMPPAATPPSP----KGGLATPPHKGAPTTPAATPP 1134
Query: 232 VGRG--------GGPARECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQG 283
+G G P GL P P + A G L P+G
Sbjct: 1135 SPKGGLATPPPKGAPTTPAATPPSPKGGLATPPP-KGAPTTPAATPPSPKGGLATPSPKG 1193
Query: 284 SMNLDSGSLKLGDAFRPASRSRSASGEVLGSWGGSGGTIP-----IVQAVPQGAET---- 334
+ + A P+ + A+ G+ T P + P+GA T
Sbjct: 1194 APTTPA-------ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1246
Query: 335 --PRPLFQTKLSRFLPQKEAAVMYPAELPQS-----SPADSEQRVSETCIVPAWLPSLPD 387
P P K P + A PA P S + + + + P P
Sbjct: 1247 TPPSP----KGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPA 1302
Query: 388 EVFLEEAPLVRMRSPPDPHASQGPPASVHASDQPYGTGLGQRTGQVTVPTEYPLHECPGT 447
+ AP +PP P S G P A P T + G T+P P +
Sbjct: 1303 TSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPK-GTPTLPA-----TTPSS 1356
Query: 448 AGADDCWQGVNGSVGISRPTSH-------TPTGTANDNIPTIDPTGLTTNPPTAAESDLL 500
G G + SH P+ IP+ P G T+P S
Sbjct: 1357 KGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPS--PKGDPTSPAVIPLSP-- 1412
Query: 501 KPVPADALGLSGNDTPGPSHNT---------ALARGTGQPGSRPTWPSQCLEELVQELAR 551
K PA + G TP T A T P P PS ++
Sbjct: 1413 KKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPS----------SK 1462
Query: 552 LDPSLCDPLASQPSPEPP 569
DP+L P + PSP+ P
Sbjct: 1463 GDPTL--PAVTPPSPKEP 1478
Score = 40.4 bits (93), Expect = 0.007
Identities = 114/501 (22%), Positives = 144/501 (28%), Gaps = 109/501 (21%)
Query: 83 PRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAAEAEAAAQAVEPPSPPASRAAYR 142
P+ P + + P P E P TP P +A A ++ SP +RA
Sbjct: 882 PKETPTPSVVNLPFPKEGPATPAP---------------KQAPALSMTSSSPKKARATPA 926
Query: 143 QRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPPATHPRSASLSHPGGEGEPARSR 202
+ +PA P PPA P S GG P+
Sbjct: 927 PK---------------------GIPASPSPKGAPTPPAATPPSPK----GGPATPSPKW 961
Query: 203 APAPGTA----GRGPLANQQRKWCFSEPGKLDRVGRGGGPARECLGEACSSSGLPGPEPL 258
AP P A +G A K + P + GGPA A + + P P
Sbjct: 962 APTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPK-GGPATPSPKGAPTPPAVTPPSPK 1020
Query: 259 EFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRPASRSRSASGEVLGSWGGS 318
PA F T P + + L G PA+ S G
Sbjct: 1021 --GSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKG--------- 1069
Query: 319 GGTIPIVQA--VPQGAETPRPLFQTKLSRFLPQKEAAVMYPAELPQSSPADSEQRVSETC 376
G P ++ P A P P K P + A M PA P S
Sbjct: 1070 GPATPSLKGAPTPPAATPPSP----KGGPATPSPKGAPMPPAATPPSPKGG--------- 1116
Query: 377 IVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQPYGTGLGQRTGQVTVP 436
L + P + AP +PP P P A P T + G T P
Sbjct: 1117 -----LATPPH----KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPP 1167
Query: 437 TEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIP-----TIDPTGLTTNP 491
+ P T A G + P T A P T P G T P
Sbjct: 1168 PK----GAPTTPAATP--PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1221
Query: 492 ---PTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQCLEELVQE 548
P + + L P P A P P A T P PT P
Sbjct: 1222 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPA----TPPPKGAPTPP---------- 1267
Query: 549 LARLDPSLCDPLASQPSPEPP 569
A PSL LA+ P P
Sbjct: 1268 -AATPPSLKGGLATPPHKGAP 1287
Score = 34.3 bits (77), Expect = 0.50
Identities = 34/147 (23%), Positives = 54/147 (36%), Gaps = 9/147 (6%)
Query: 68 GGPGPAP---PDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAAEAEA 124
G P P P A SP+ P A + P P + P TP P +P + + +
Sbjct: 1592 GAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSP 1651
Query: 125 AAQA-----VEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARP 179
+ A + P AS+ ++ A + VL + + + ++ P R P
Sbjct: 1652 TSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPI-ITAPTRKGPQTKKSS 1710
Query: 180 PATHPRSASLSHPGGEGEPARSRAPAP 206
+ P S G P + APAP
Sbjct: 1711 ATSPPICPDPSAKNGSKGPLSTVAPAP 1737
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 49.3 bits (116), Expect = 2e-05
Identities = 120/501 (23%), Positives = 162/501 (32%), Gaps = 59/501 (11%)
Query: 72 PAPPDAALCTSPRPRPAVAARSGPQPTEVP-GTPGPLNRQATPLLYALAAEAEAAAQAVE 130
P PD + + + V G P G GP R P L
Sbjct: 93 PVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPG---- 148
Query: 131 PPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPAR---PPATHPRSA 187
PP PP + +L ++ +S+P + P+ P PP
Sbjct: 149 PPGPPGLGGNFAPQLSYGYD--------EKSTGGISVPGPMGPSGPRGLPGPPGAPGPQG 200
Query: 188 SLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPARECLGEAC 247
PG GEP S P RGP + E GK R G G P +
Sbjct: 201 FQGPPGEPGEPGASGPMGP----RGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLP 256
Query: 248 SSSGLPGPEPLE-FQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRPASRSRS 306
++GLPG + F AK + G P+ +P GS + ++G P R R
Sbjct: 257 GTAGLPGMKGHRGFSGLDGAKGDAGPAG--PKGEP-GSPGENGAPGQMGPRGLPGERGRP 313
Query: 307 ASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYP--AELPQSS 364
+ G+ G G T P G P P F + + EA P +E PQ
Sbjct: 314 GAPGPAGARGNDGATGAAGPPGPTGPAGP-PGFPGAVG---AKGEAGPQGPRGSEGPQGV 369
Query: 365 PADSEQRVSETCIVPAWLPSL---PDEVFLEEAPLVR-------MRSPPDPHASQGPPAS 414
+ PA P P AP + R P P GPP
Sbjct: 370 RGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGP 429
Query: 415 VHASDQPYGTGLGQRTGQVTVPTEYPLHECPGTAGADD--CWQGVNGSVGISRPTSHTPT 472
S +P G TG P + PG AG + +G G G+ P
Sbjct: 430 KGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGER-G 488
Query: 473 GTANDNIPTID-------PTGLTTNP----PTAAESDLLKPVPA---DALGLSGN-DTPG 517
G + P D P G +P P + + +P A A GL+G+ +PG
Sbjct: 489 GPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPG 548
Query: 518 PSHNTALARGTGQPGSRPTWP 538
P T GQ G RP P
Sbjct: 549 PDGKTGPPGPAGQDG-RPGPP 568
Score = 38.9 bits (89), Expect = 0.020
Identities = 62/261 (23%), Positives = 80/261 (30%), Gaps = 46/261 (17%)
Query: 5 GPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASG-----GPEPRTQSPGT---DLLP 56
GP G+R SP + ++ +G GP+ +T PG D P
Sbjct: 506 GPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRP 565
Query: 57 YLDWDYVRVVWGGPGP--APPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPL 114
G PGP A A + P P+ A VPG PG +
Sbjct: 566 -----------GPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVG------ 608
Query: 115 LYALAAEAEAAAQAVEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPT 174
+ EA AQ P+ PA + ++ FQ LP P
Sbjct: 609 --PAGKDGEAGAQGPPGPAGPAG--------ERGEQGPAGSPGFQ------GLPGPAGPP 652
Query: 175 VPARPPATHPRSASLSHPGGEGEPARSRAPAPGTAG-RGPLANQQRKWCFSEPGKLDRVG 233
A P L PG G AR PG G +GP + PG G
Sbjct: 653 GEAGKPGEQGVPGDLGAPGPSG--ARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKG 710
Query: 234 RGGGPARECLGEACSSSGLPG 254
G P A G+PG
Sbjct: 711 DAGAPGAPGSQGAPGLQGMPG 731
Score = 36.2 bits (82), Expect = 0.13
Identities = 69/278 (24%), Positives = 89/278 (32%), Gaps = 45/278 (16%)
Query: 5 GPGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASG-----GPEPRTQSPGTDLLPYLD 59
GP G R P T+ L M+ +S A G GP+ SPG + P
Sbjct: 248 GPQGARGLPG--TAGLP----GMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAP--- 298
Query: 60 WDYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATP-LLYAL 118
G GP P PA AR T G PGP P A+
Sbjct: 299 --------GQMGPRGLPGERGRPGAPGPA-GARGNDGATGAAGPPGPTGPAGPPGFPGAV 349
Query: 119 AAEAEAAAQAV-----------EPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMS- 166
A+ EA Q EP P + AA GA + + + + +
Sbjct: 350 GAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAP 409
Query: 167 -LPARLRPTVP---ARPPATHPRSASLSHPGGEGEPARSRAPAP-GTAG-RGPLANQQRK 220
P P+ P PP S PG +G+ P P G G GP + ++
Sbjct: 410 GFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKR 469
Query: 221 WCFSEPGKL---DRVGRGGGPARECLGEACSSSGLPGP 255
EPG G GGP A +G GP
Sbjct: 470 GARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGP 507
Score = 33.5 bits (75), Expect = 0.85
Identities = 50/186 (26%), Positives = 62/186 (33%), Gaps = 23/186 (12%)
Query: 68 GGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAAEAEAAAQ 127
G PGPA + PR A R G PG PGP + +P A+ A A
Sbjct: 896 GPPGPAGKEGG--KGPRGETGPAGRPGE--VGPPGPPGPAGEKGSP-----GADGPAGAP 946
Query: 128 AVEPPSPPASRAAY----RQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPP--A 181
P A + QR + + + K+ P P PP A
Sbjct: 947 GTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLA 1006
Query: 182 THP-RSASLSHPGGEGEPARSRAP-APGTAGR-GPLANQQRKWCFSEPGKLDRVGRGG-- 236
P S PG EG P R +P A G G GP PG + G+ G
Sbjct: 1007 GPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDR 1066
Query: 237 ---GPA 239
GPA
Sbjct: 1067 GETGPA 1072
Score = 31.2 bits (69), Expect = 4.2
Identities = 39/146 (26%), Positives = 49/146 (33%), Gaps = 20/146 (13%)
Query: 402 PPDPHASQGPPASVHASDQPYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSV 461
PP P + GPP + + G G TG P E PG AG G +G
Sbjct: 885 PPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGS-PGADGPA 943
Query: 462 GISRPTSHTPTGTAND-------------NIPTI-DPTGLT-TNPPTAAESDLLKPVPAD 506
G P + P G A P + P+G P+ A + P P
Sbjct: 944 G--APGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMG 1001
Query: 507 ALGLSGNDTPGPSHNTALARGTGQPG 532
GL+G PG S G PG
Sbjct: 1002 PPGLAG--PPGESGREGAPGAEGSPG 1025
>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
Length = 863
Score = 48.9 bits (115), Expect = 2e-05
Identities = 99/401 (24%), Positives = 134/401 (33%), Gaps = 82/401 (20%)
Query: 4 LGPG---GDRASPASSTSSLDLWHLSMRADSAYS---SFSAASGG--------PEPRTQS 49
LGPG G R P S L+ A S SA +G PE R Q
Sbjct: 221 LGPGTRSGTRPGPFSQPKQQHQQQLAEDAKDVPGGGPSSSAPAGAEADGPKASPEARPQI 280
Query: 50 PGTDLLPYLDWDYVRVVWGGPGPAPPDAALCTSP-----RPR------------------ 86
P +P + G P PAP A+ T+P RPR
Sbjct: 281 PTKPRVPGKLQELASPPAGRPTPAPRKASESTTPAPPTPRPRSSLQQENLVEQAGSSSLV 340
Query: 87 -------PAVAARSGPQPTEVPGTPGPLNRQATPLLYALAAEAEAAAQAVEPPSPPASRA 139
P R P+P+E GTP P R+ P + + AE + + P S P +
Sbjct: 341 NGRLHELPVPKPRGTPKPSE--GTPAP--RKDPPWITLVQAEPKKKPAPLPPSSSPGPPS 396
Query: 140 AYRQRLQGAQRRVLRETS------------FQRKELRMSLPARLRPTVPARPPATHPRSA 187
++++ + + S F+ +E A P++ P HP S
Sbjct: 397 QDSRQVENGGTEEVAQPSPTASLESKPYNPFEEEEEDKEEEAPAAPSLATSPALGHPEST 456
Query: 188 SLS-HPG----GEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPAREC 242
S HP P + PAP PLA + SEP P+
Sbjct: 457 PKSLHPWYGITPTSSPKTKKRPAPRAPSASPLALHASRLSHSEP-------PSATPSPAL 509
Query: 243 LGEACSS---SGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQG-SMNLDSGSLKLGDAF 298
E+ SS S G E LE PA+ K P T S++ +S G+
Sbjct: 510 SVESLSSESASQTAGAELLE--PPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLASSGELV 567
Query: 299 RP-ASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPL 338
P + AS + GS G P A P TP PL
Sbjct: 568 EPRVEQMPQASPGLAPRTRGSSGPQP---AKPCSGATPTPL 605
Score = 32.3 bits (72), Expect = 1.9
Identities = 30/129 (23%), Positives = 48/129 (37%), Gaps = 16/129 (12%)
Query: 31 SAYSSFSAASGGPEPRTQSPGTDLLPYLDWDYVRVVWGGPGPAPPDAALCTSPRPRPAVA 90
S SS +++ EPR + +P G GP P +P P V
Sbjct: 555 STNSSLASSGELVEPRVEQ-----MPQASPGLAPRTRGSSGPQPAKPCSGATPTPLLLVG 609
Query: 91 ARSGPQPTEVPGTP----------GPLNRQATPLLYALAAEAEAAAQAVEPPSPPASRAA 140
RS P P+ +P P NR+ +P +A ++ V PP+P
Sbjct: 610 DRS-PVPSPGSSSPQLQVKSSCKENPFNRKPSPAASPATKKATKGSKPVRPPAPGHGFPL 668
Query: 141 YRQRLQGAQ 149
++++Q Q
Sbjct: 669 IKRKVQADQ 677
Score = 30.0 bits (66), Expect = 9.4
Identities = 79/387 (20%), Positives = 129/387 (33%), Gaps = 48/387 (12%)
Query: 328 VPQGAETPRPLFQTKLSR----------FLPQKEAAVMYPAELPQSSPADSEQRVS---E 374
VP+ TP+P T R P+K+ A + P+ P DS Q + E
Sbjct: 349 VPKPRGTPKPSEGTPAPRKDPPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTE 408
Query: 375 TCIVP---AWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQPYGTGLGQRTG 431
P A L S P F EE +P P + P A P T
Sbjct: 409 EVAQPSPTASLESKPYNPFEEEEEDKEEEAPAAPSLATSP-----ALGHPESTPKSLHPW 463
Query: 432 QVTVPTEYP-LHECPGTAGADDCWQGVNGS-VGISRPTSHTPTGTANDNIPTIDPTGLTT 489
PT P + P ++ S + S P S TP+ P + L++
Sbjct: 464 YGITPTSSPKTKKRPAPRAPSASPLALHASRLSHSEPPSATPS-------PALSVESLSS 516
Query: 490 NPPT-AAESDLLKP--VPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQCLEELV 546
+ A ++LL+P VP + + + P + +L+ + S + +E V
Sbjct: 517 ESASQTAGAELLEPPAVPKSSSEPAVHAPGTPGNPVSLSTNSSLASS-----GELVEPRV 571
Query: 547 QELARLDPSLCDPLASQPSPEPPLGLLDGLIPLAEVRAAMRPACGEAGEEAASTFEPGSY 606
+++ + P L P+P G P + R G + S
Sbjct: 572 EQMPQASPGLAPRTRGSSGPQPAKPC-SGATPTPLLLVGDRSPVPSPGSSSPQLQVKSSC 630
Query: 607 QFSFTQLLPAPREE--TRLENPATHPVLDQPCGQGLPAPNNSIQGKKVELAARLQKMLQD 664
+ + P+P T+ + PV G G P +Q + +D
Sbjct: 631 KENPFNRKPSPAASPATKKATKGSKPVRPPAPGHGFPLIKRKVQADQYIPE-------ED 683
Query: 665 LHTEQERLQGEAQAWARRQAALEAAVR 691
+H E + ++ A R LE +R
Sbjct: 684 IHGEMDTIERRLDALEHRGVLLEEKLR 710
>gi|24797153 faciogenital dysplasia protein [Homo sapiens]
Length = 961
Score = 48.5 bits (114), Expect = 3e-05
Identities = 92/333 (27%), Positives = 117/333 (35%), Gaps = 50/333 (15%)
Query: 192 PGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGG-----------GPAR 240
PGG G P+ PA G P A SEPG L R G G GP+
Sbjct: 7 PGGAG-PSEPEHPATNPPGAAPPACADSDPGASEPGLLARRGSGSALGGPLDPQFVGPSD 65
Query: 241 ECLGEACSSSGLP-GPEPLEFQHPALAKFEDHEVGWLPET-QPQGSMNL-DSGSLKLGDA 297
LG A LP GP P QH +F H G P QG+ L S SL G +
Sbjct: 66 TSLGAAPGHRVLPCGPSP---QHHRALRFSYHLEGSQPRPGLHQGNRILVKSLSLDPGQS 122
Query: 298 FRPASRSRSASGEVLGSWGGSGGTIPIVQAVP-QGAETPRPLFQTKLSRFLPQKEAAVMY 356
P + L S G P + P + A P+P K S + +
Sbjct: 123 LEP----HPEGPQRLRSDPGPPTETPSQRPSPLKRAPGPKPQVPPKPSYLQMPRMPPPLE 178
Query: 357 PAELPQSSPADSEQRV-------SETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQ 409
P P S P ++ RV +E A + SL ++ E P++ P P S
Sbjct: 179 PIPPPPSRPLPADPRVAKGLAPRAEASPSSAAVSSLIEK--FEREPVIVASDRPVPGPSP 236
Query: 410 GPPASVHASDQPYGTGLGQRTGQVTVP--TEYPLHEC-----PGTAGADDCWQGVNGSVG 462
GPP V L Q T Q VP E C PG + +G
Sbjct: 237 GPPEPVM---------LPQPTSQPPVPQLPEGEASRCLFLLAPGPRDGEKVPNRDSGIDS 287
Query: 463 ISRPTSHTPTGTANDNIPTIDPTGLTTNPPTAA 495
IS P++ T +D+ P L PP A
Sbjct: 288 ISSPSNSEETCFVSDDGP--PSHSLCPGPPALA 318
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 48.5 bits (114), Expect = 3e-05
Identities = 133/604 (22%), Positives = 195/604 (32%), Gaps = 84/604 (13%)
Query: 102 GTPGPLNRQATPLLYALAAEAEAAAQAVEPPSP---PASRAAYRQRLQGAQRRVLRETSF 158
G L + P A AA A A PS PA A +L +RR +
Sbjct: 2 GNEASLEGEGLPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMS 61
Query: 159 QRKELRMSLPARLRPTVPARPPATHPRSA-SLSHPGGEGEPARSRAPAPGTAGRGPLANQ 217
+ + LP P A P+ H + SHP + R P PG + L+
Sbjct: 62 RAQ----GLPKGSVPPAAAESPSMHRKQELDSSHPPKQS----GRPPDPGRPAQPGLSKS 113
Query: 218 QRKWCFSEPGKL-----DRVGRGGGPARECLGEACSSSGLPG----PEPLEFQHPALAKF 268
+ F KL + +R L E SS +PG L + KF
Sbjct: 114 RTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKF 173
Query: 269 E------DHEVGWLPETQPQGSMNLDSGSLKLGDAFRPASRSRSASGEVLGSWGGSGGTI 322
D E T+ Q + + G K +P + + + + G G
Sbjct: 174 NPFDLISDSEASQEETTKKQKVVQKEQG--KPEGIIKPPLQQQPP--KPIPKQQGPGRDP 229
Query: 323 PIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAELPQSSPAD-------SEQRVSET 375
P+ + +P K+ P + P + PQ+ A S + +
Sbjct: 230 LQQDGTPKSISSQQP---EKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQA 286
Query: 376 CIV--PAWLPSLPDEVFLEEAPLVRMRSPPDPHASQ-----GPPASVHASDQPYGTG--L 426
IV + PSLP P ++ +P P A Q P QP G L
Sbjct: 287 DIVRGESVKPSLPSP----SKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPL 342
Query: 427 GQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIPTIDPTG 486
Q+ G V P + P P G +P+S P A P + T
Sbjct: 343 AQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQ-QTGSEKPSSEQPGPKALAQPPGVGKTP 401
Query: 487 -------------LTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGS 533
+ T P A + L P A + PGP A G G+ +
Sbjct: 402 AQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSA 461
Query: 534 RPTWPSQCLEEL--VQELARLDPSLCDPLASQP-SPEPPLGLLDGLIPLAEVRAAMRPAC 590
+ T P++ +L + P P QP S +PP P + +P+
Sbjct: 462 QQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSP 521
Query: 591 GEAGEEAASTFEPGSYQFSFTQLLPA---------PREET----RLENPATHPVLDQPCG 637
+ G + +PGS + S Q PA P +T L+ P P QP
Sbjct: 522 QQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPS 581
Query: 638 QGLP 641
QGLP
Sbjct: 582 QGLP 585
Score = 41.2 bits (95), Expect = 0.004
Identities = 61/226 (26%), Positives = 82/226 (36%), Gaps = 38/226 (16%)
Query: 40 SGGPEPRTQSPGTDLLPYLDWDYVRVVWGGPGPAPPDAALCTSPRPR------------P 87
SG +P Q PGT P + GPA P A S +P P
Sbjct: 336 SGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPP 395
Query: 88 AV----AARSGPQ--PTEVPGTPGPLNRQATPLLYALAAEAEAAAQAVEPPSP---PASR 138
V A + GP PT+ GTP PL +Q P L + A V+ P P PA +
Sbjct: 396 GVGKTPAQQPGPAKPPTQQVGTPKPLAQQ--PGLQSPAKAPGPTKTPVQQPGPGKIPAQQ 453
Query: 139 AAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTV--PARPPATHPRSAS--LSHPGG 194
A G + ++T + ++ PA+ P PA+PP P SA PG
Sbjct: 454 A-------GPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGS 506
Query: 195 EGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPAR 240
P + PG A P K +PG + PA+
Sbjct: 507 TKPPPQQ----PGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAK 548
Score = 32.0 bits (71), Expect = 2.5
Identities = 76/394 (19%), Positives = 132/394 (33%), Gaps = 91/394 (23%)
Query: 70 PGPAPPDAALCTSPRPRPAVAARSGPQPTEV-----------------PGTPGPLNRQAT 112
P P+ P L T+P + ++S PQP + P P PL +Q
Sbjct: 652 PVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQ-- 709
Query: 113 PLLY---ALAAEAEAAAQAVEPPSPPASRAAYRQRLQGA-------QRRVLRETSFQRKE 162
P L+ + A+ A ++ P+PP + ++ + Q ++++ T+ +
Sbjct: 710 PTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTT----D 765
Query: 163 LRMSLPARLRPTVPARPPATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWC 222
L S A +P +P+ ++ + P + + A+ P T G +
Sbjct: 766 LVSSSSATTKPDIPSSK--VQSQAEEKTTPPLKTDSAKPSQSFPPT---GEKVSPFDSKA 820
Query: 223 FSEPGKLDRVGRGGGPARECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQ 282
P ++ GP+ E G+ EP + Q K P+ +P
Sbjct: 821 IPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPK---------PDAKP- 870
Query: 283 GSMNLDSGSLKLGDAFRPASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTK 342
+ G P R + G T+P Q P+ E R F
Sbjct: 871 ---------MPKGSPTPPGPRPTA------------GQTVPTPQQSPKPQEQSRR-FSLN 908
Query: 343 LSRFLPQKEAAVMYPAELPQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSP 402
L + P+S P ++ V+ L +F + + L+
Sbjct: 909 LGSI-----------TDAPKSQPTTPQETVTGK------LFGFGASIFSQASNLISTAGQ 951
Query: 403 PDPHASQGPPASVH----ASDQPYGTGLGQRTGQ 432
P PH+ GP A + S P G + TGQ
Sbjct: 952 PGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQ 985
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 48.5 bits (114), Expect = 3e-05
Identities = 133/604 (22%), Positives = 195/604 (32%), Gaps = 84/604 (13%)
Query: 102 GTPGPLNRQATPLLYALAAEAEAAAQAVEPPSP---PASRAAYRQRLQGAQRRVLRETSF 158
G L + P A AA A A PS PA A +L +RR +
Sbjct: 2 GNEASLEGEGLPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMS 61
Query: 159 QRKELRMSLPARLRPTVPARPPATHPRSA-SLSHPGGEGEPARSRAPAPGTAGRGPLANQ 217
+ + LP P A P+ H + SHP + R P PG + L+
Sbjct: 62 RAQ----GLPKGSVPPAAAESPSMHRKQELDSSHPPKQS----GRPPDPGRPAQPGLSKS 113
Query: 218 QRKWCFSEPGKL-----DRVGRGGGPARECLGEACSSSGLPG----PEPLEFQHPALAKF 268
+ F KL + +R L E SS +PG L + KF
Sbjct: 114 RTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKF 173
Query: 269 E------DHEVGWLPETQPQGSMNLDSGSLKLGDAFRPASRSRSASGEVLGSWGGSGGTI 322
D E T+ Q + + G K +P + + + + G G
Sbjct: 174 NPFDLISDSEASQEETTKKQKVVQKEQG--KPEGIIKPPLQQQPP--KPIPKQQGPGRDP 229
Query: 323 PIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAELPQSSPAD-------SEQRVSET 375
P+ + +P K+ P + P + PQ+ A S + +
Sbjct: 230 LQQDGTPKSISSQQP---EKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQA 286
Query: 376 CIV--PAWLPSLPDEVFLEEAPLVRMRSPPDPHASQ-----GPPASVHASDQPYGTG--L 426
IV + PSLP P ++ +P P A Q P QP G L
Sbjct: 287 DIVRGESVKPSLPSP----SKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPL 342
Query: 427 GQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIPTIDPTG 486
Q+ G V P + P P G +P+S P A P + T
Sbjct: 343 AQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQ-QTGSEKPSSEQPGPKALAQPPGVGKTP 401
Query: 487 -------------LTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGS 533
+ T P A + L P A + PGP A G G+ +
Sbjct: 402 AQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSA 461
Query: 534 RPTWPSQCLEEL--VQELARLDPSLCDPLASQP-SPEPPLGLLDGLIPLAEVRAAMRPAC 590
+ T P++ +L + P P QP S +PP P + +P+
Sbjct: 462 QQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSP 521
Query: 591 GEAGEEAASTFEPGSYQFSFTQLLPA---------PREET----RLENPATHPVLDQPCG 637
+ G + +PGS + S Q PA P +T L+ P P QP
Sbjct: 522 QQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPS 581
Query: 638 QGLP 641
QGLP
Sbjct: 582 QGLP 585
Score = 41.2 bits (95), Expect = 0.004
Identities = 61/226 (26%), Positives = 82/226 (36%), Gaps = 38/226 (16%)
Query: 40 SGGPEPRTQSPGTDLLPYLDWDYVRVVWGGPGPAPPDAALCTSPRPR------------P 87
SG +P Q PGT P + GPA P A S +P P
Sbjct: 336 SGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPP 395
Query: 88 AV----AARSGPQ--PTEVPGTPGPLNRQATPLLYALAAEAEAAAQAVEPPSP---PASR 138
V A + GP PT+ GTP PL +Q P L + A V+ P P PA +
Sbjct: 396 GVGKTPAQQPGPAKPPTQQVGTPKPLAQQ--PGLQSPAKAPGPTKTPVQQPGPGKIPAQQ 453
Query: 139 AAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTV--PARPPATHPRSAS--LSHPGG 194
A G + ++T + ++ PA+ P PA+PP P SA PG
Sbjct: 454 A-------GPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGS 506
Query: 195 EGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPAR 240
P + PG A P K +PG + PA+
Sbjct: 507 TKPPPQQ----PGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAK 548
Score = 32.0 bits (71), Expect = 2.5
Identities = 76/394 (19%), Positives = 132/394 (33%), Gaps = 91/394 (23%)
Query: 70 PGPAPPDAALCTSPRPRPAVAARSGPQPTEV-----------------PGTPGPLNRQAT 112
P P+ P L T+P + ++S PQP + P P PL +Q
Sbjct: 652 PVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQ-- 709
Query: 113 PLLY---ALAAEAEAAAQAVEPPSPPASRAAYRQRLQGA-------QRRVLRETSFQRKE 162
P L+ + A+ A ++ P+PP + ++ + Q ++++ T+ +
Sbjct: 710 PTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTT----D 765
Query: 163 LRMSLPARLRPTVPARPPATHPRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWC 222
L S A +P +P+ ++ + P + + A+ P T G +
Sbjct: 766 LVSSSSATTKPDIPSSK--VQSQAEEKTTPPLKTDSAKPSQSFPPT---GEKVSPFDSKA 820
Query: 223 FSEPGKLDRVGRGGGPARECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQ 282
P ++ GP+ E G+ EP + Q K P+ +P
Sbjct: 821 IPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPK---------PDAKP- 870
Query: 283 GSMNLDSGSLKLGDAFRPASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTK 342
+ G P R + G T+P Q P+ E R F
Sbjct: 871 ---------MPKGSPTPPGPRPTA------------GQTVPTPQQSPKPQEQSRR-FSLN 908
Query: 343 LSRFLPQKEAAVMYPAELPQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSP 402
L + P+S P ++ V+ L +F + + L+
Sbjct: 909 LGSI-----------TDAPKSQPTTPQETVTGK------LFGFGASIFSQASNLISTAGQ 951
Query: 403 PDPHASQGPPASVH----ASDQPYGTGLGQRTGQ 432
P PH+ GP A + S P G + TGQ
Sbjct: 952 PGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQ 985
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 48.1 bits (113), Expect = 3e-05
Identities = 137/554 (24%), Positives = 170/554 (30%), Gaps = 108/554 (19%)
Query: 71 GPAPPDAALCTSPRPRPAVAAR---------SGPQPTEVPG------TPGPLNRQATPLL 115
GP +P RP + R + P P PG PGPL ++ L
Sbjct: 78 GPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG---L 134
Query: 116 YALAAEAEAAAQAVEPPSPPASRAAYRQRLQG-----AQRRVLRETSFQRKELRMSLPAR 170
A E A +A E P A A R+ G + R + E+ + PA
Sbjct: 135 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA- 193
Query: 171 LRPTVPARPPATHPR---SASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWC--FSE 225
P+ RPP PR S++ H E PA R P+ G + P + S
Sbjct: 194 --PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 251
Query: 226 PGKLDRVGRG--GGPARECLGEACSSSGLPGPE---PLEFQHPALAKFEDHEVGWLPETQ 280
P + RG PA + L P+ P + PAL P
Sbjct: 252 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS-----PLAT 306
Query: 281 PQGSMNLDSGSLKLGDAFRPASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQ 340
P S L S + A +S L S P +Q +P TP
Sbjct: 307 PSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAT 366
Query: 341 TKLS--------RFLPQ-------------KEAAVMYPAELPQSSPADSEQRVSETCIVP 379
T L FLP A + P + P S PA T P
Sbjct: 367 TSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLAT---P 423
Query: 380 AWLPSLPD--EVFLEEAPLVRMRSPPDPHASQGPPASVHASDQPYGTGLGQRTGQVTVPT 437
+ P P+ V L +AP SPP A PPAS S P T Q + P
Sbjct: 424 S--PQAPNALAVHLLQAPFSPPPSPP-VQAPFSPPASPPVS--PSATPPSQAPPSLAAP- 477
Query: 438 EYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIPTIDPTGLTTNPPTAAES 497
PL P S S P S + T P P PP A
Sbjct: 478 --PLQVPP--------------SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP 521
Query: 498 DLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQCL--EELVQELARLDPS 555
L P P AL P P PG P PS L L + P
Sbjct: 522 ALATP-PLQAL-------PSPP--------ASFPGQAPFSPSASLPMSPLATPPPQAPPV 565
Query: 556 LCDPLASQPSPEPP 569
L PL P P PP
Sbjct: 566 LAAPLLQVP-PSPP 578
Score = 46.2 bits (108), Expect = 1e-04
Identities = 117/475 (24%), Positives = 153/475 (32%), Gaps = 46/475 (9%)
Query: 81 TSPRPRPAVAARSGPQPTEVP-GTPGPLNRQATPLLYALAAEAEAAAQAVEPPSPPASRA 139
T P PA+A RS TEV P P R P + + A+ + PSP A R
Sbjct: 168 TPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 227
Query: 140 AYRQRLQGAQRRVLRETSFQRKEL----RMSLPARLRPTVPARPPATHPRSASLSHPGGE 195
G QR R S L R AR P PA P P+ P
Sbjct: 228 PSAGG--GLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQV 285
Query: 196 GEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPARECLGEACSSSGLPGP 255
P + APA G PLA + C ++ LP
Sbjct: 286 TPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQ----LATPLPLA 341
Query: 256 EPLEFQHPALAKFEDHEVGWLPETQP-QGSMNLDSGSLKLGDAFRPASRSRSASGEVLGS 314
P P+L P T P Q + +L S +L+ +F P+ +
Sbjct: 342 PPSPSAPPSLQTLPSP-----PATPPSQATTSLGSPTLQATHSFLPSPPLSPLA--TPPP 394
Query: 315 WGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQ-KEAAVMYPAELPQSSPADSEQRVS 373
+P +QA P +P PL + L+ PQ A ++ + P S P V
Sbjct: 395 QAPPALALPPLQAPPSPPASP-PL--SPLATPSPQAPNALAVHLLQAPFSPPPSPP--VQ 449
Query: 374 ETCIVPAWLPSLPDEVFLEEAP----LVRMRSPPDPHASQGPPASVHASDQPYG-TGLGQ 428
PA P P +AP ++ PP P AS PP S A+ P L
Sbjct: 450 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS--PPMSPSATPPPQAPPPLAA 507
Query: 429 RTGQVTVPTEY--PLHECPGTAGADDCWQGVNGSVGISRPTS--HTPTGTANDNIPTIDP 484
Q+ P P P G S S +P T P +
Sbjct: 508 PPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 567
Query: 485 TGLTTNPPTAAESDLLK-----PVPADALGLSGNDTPGPSHNTALARGTGQPGSR 534
L PP+ S L+ P P +S GP ALA G P SR
Sbjct: 568 APLLQVPPSPPASPTLQAPRRPPTPGPDTSVS-----GPRLTLALAPGPPPPPSR 617
Score = 45.8 bits (107), Expect = 2e-04
Identities = 138/613 (22%), Positives = 191/613 (31%), Gaps = 130/613 (21%)
Query: 132 PSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPPATHPRSASLSH 191
P PP + AA R + GA V R+ L R A P + PR+
Sbjct: 35 PPPPVTPAALR--VLGAAGAVGRKP----------LAERAGGIGGATIPESAPRAGPTRS 82
Query: 192 PGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGG--------------- 236
G SR PA G R P A S PG+ R G
Sbjct: 83 AGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV 142
Query: 237 -------GPARECLG------------------------EACSSSGLPGPEPLEFQHP-- 263
P R L A + GLP P P P
Sbjct: 143 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 202
Query: 264 -----ALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRPASRSRSASGEVLGSWGGS 318
+++ +H E P +G G RPASRS S+S L S S
Sbjct: 203 EGPRKSVSSASEHST---TEPSPAARRRPSAG----GGLQRPASRSLSSSATPLSSPARS 255
Query: 319 GGTIPIVQAVPQGAETPRP--LFQTKLSRFLPQKEAAVMYPAELPQSSPADSEQRVSETC 376
G + P P+P L + + P ++ A L S A +
Sbjct: 256 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQS 315
Query: 377 IVPAWLPSLPDEVFLE-EAPLVRMRSPPDPHASQGPPASVHASDQPYGTGLGQRTGQVTV 435
P LP+ P L + +PP P A P S+ P T Q T +
Sbjct: 316 QAPPTLPATPHSSSLTCQLATPLPLAPPSPSA----PPSLQTLPSPPATPPSQATTSLGS 371
Query: 436 PTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIPTIDPTGLTTNPPTAA 495
PT H + ++ P P A + P +PP +
Sbjct: 372 PTLQATHSFLPSPPLSP----------LATPPPQAPPALA------LPPLQAPPSPPASP 415
Query: 496 E-SDLLKPVP--ADALGLSGNDTP-GPSHNTALARGTGQPGSRP-----TWPSQCLEELV 546
S L P P +AL + P P + + P S P T PSQ L
Sbjct: 416 PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA 475
Query: 547 QELARLDPS--LCDPL--ASQPSPEPPLGLLDGLIPLAEVRAAMRPACG----EAGEEAA 598
++ PS P+ ++ P P+ P L + LA+ PA +A
Sbjct: 476 APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPP 535
Query: 599 STFEPGSYQFSFTQLLP----------------APREETRLENPATHPVLDQPCGQGLPA 642
++F PG FS + LP AP + PA+ P L P P
Sbjct: 536 ASF-PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS-PTLQAPRRPPTPG 593
Query: 643 PNNSIQGKKVELA 655
P+ S+ G ++ LA
Sbjct: 594 PDTSVSGPRLTLA 606
Score = 35.4 bits (80), Expect = 0.22
Identities = 45/155 (29%), Positives = 59/155 (38%), Gaps = 18/155 (11%)
Query: 70 PGPAPPDAALCTSP-RPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAAEAEAAAQA 128
P +PP + T P + P++AA P P +P P++ ATP A A Q
Sbjct: 454 PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP-PMSPSATPPPQAPPPLAAPPLQL 512
Query: 129 VEPP--SPPASRAAYRQRLQGAQRRVLRETSFQ-RKELRMS---LPARLRPTVPARP--- 179
+PP +PPA Q L + F L MS P P V A P
Sbjct: 513 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 572
Query: 180 -PATHPRSASLSHPGGEGEPARSRAPAPGTAGRGP 213
P + P S +L P R P P T+ GP
Sbjct: 573 VPPSPPASPTLQ------APRRPPTPGPDTSVSGP 601
Score = 30.0 bits (66), Expect = 9.4
Identities = 47/196 (23%), Positives = 69/196 (35%), Gaps = 20/196 (10%)
Query: 7 GGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSP-GTDLL-------PYL 58
GG PAS + S LS A S S+ P P G L P
Sbjct: 231 GGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK 290
Query: 59 DWDYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYAL 118
D P P ++ +P P A+ +++ P P + + ATPL L
Sbjct: 291 D--------AAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPL--PL 340
Query: 119 AAEAEAAAQAVEP-PSPPASRAAYRQRLQGAQRRVLRETSFQRKELR-MSLPARLRPTVP 176
A + +A +++ PSPPA+ + G+ + L ++ P P
Sbjct: 341 APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL 400
Query: 177 ARPPATHPRSASLSHP 192
A PP P S S P
Sbjct: 401 ALPPLQAPPSPPASPP 416
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 48.1 bits (113), Expect = 3e-05
Identities = 144/617 (23%), Positives = 192/617 (31%), Gaps = 129/617 (20%)
Query: 71 GPAPPDAALCTSPRPRPAVAAR---------SGPQPTEVPG------TPGPLNRQATPLL 115
GP +P RP + R + P P PG PGPL ++ L
Sbjct: 78 GPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG---L 134
Query: 116 YALAAEAEAAAQAVEPPSPPASRAAYRQRLQG-----AQRRVLRETSFQRKELRMSLPAR 170
A E A +A E P A A R+ G + R + E+ + PA
Sbjct: 135 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA- 193
Query: 171 LRPTVPARPPATHPR---SASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPG 227
P+ RPP PR S++ H E PA R P+ G G L + S
Sbjct: 194 --PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG----GGLQRPASRSLSSSAT 247
Query: 228 KLDRVGRGGGPARECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNL 287
L R GP+ A + P P+ L+ P P+ P
Sbjct: 248 PLSSPAR-SGPSARGTPRAPAHPSQPKPKGLQALRP-------------PQVTP------ 287
Query: 288 DSGSLKLGDAFRPASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFL 347
P + A G + S P+ P G TK
Sbjct: 288 ------------PRKDAAPALGPLSSS--------PLATPSPSG---------TKARPVP 318
Query: 348 PQKEAAVMYPAELPQSSPADSEQRVSETCIVPAWLPSL-----PDEVFLEEAP----LVR 398
P AA PA LP S P + ++ P+ PSL P +AP
Sbjct: 319 PPDNAATPLPATLPPSPPLATPLPLAPPS--PSAPPSLQTLPSPPATPPSQAPPSMTTPP 376
Query: 399 MRSPPD---------PHASQGPPASVHASDQPYGTGLGQRTGQVTVPTEYPLHECPGTAG 449
M++PP PH+ P S+ A P Q T + PT H +
Sbjct: 377 MQAPPSLQTIPPIQVPHSLTSP--SLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSP 434
Query: 450 ADDCWQGVNGSVGISRPTSHTPTGTANDNIPTIDPTGLTTNPPTAAESDLLKPVPADALG 509
Q SRP S P D+ P P L +PP L P
Sbjct: 435 R----QTQASLTSPSRPASTPP-----DSPPLQAPLSLPASPPLQTS---LSP------A 476
Query: 510 LSGNDTPGPSHNTALARGTGQPGSRPTWPSQCLEELVQELARLDPSLCDPLASQPSPEPP 569
+S +P H + S + L + + PSL P AS + PP
Sbjct: 477 VSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTT--PP 534
Query: 570 LGLLDGLIPLAEVRAAMRPACGEAGEEAASTFEPGSYQFSFTQLLPAPRE---ETRLENP 626
L L L P ++ A P E P Q + L P E P
Sbjct: 535 LENLPSLAP-PPLQTASAPLT-TPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPP 592
Query: 627 ATHPVLDQPCGQGLPAP 643
P L P QGLP+P
Sbjct: 593 QAPPALASPPLQGLPSP 609
Score = 40.8 bits (94), Expect = 0.005
Identities = 148/635 (23%), Positives = 215/635 (33%), Gaps = 104/635 (16%)
Query: 73 APPDAALCTSPRPRPAVA---ARSGPQP----TEVPGTPGPLNRQATPLLYALAAEAEAA 125
AP L +SP P+ + AR P P T +P T P ATPL LA + +A
Sbjct: 293 APALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPL--PLAPPSPSA 350
Query: 126 AQAVEP-PSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPPATHP 184
+++ PSPPA+ + Q + P + P++ PP P
Sbjct: 351 PPSLQTLPSPPATPPS------------------QAPPSMTTPPMQAPPSLQTIPPIQVP 392
Query: 185 RSASLSHPGGEGEP---ARSRAPAPGTAGRGPL---------ANQQRKWCFSEPGKLDRV 232
S L+ P + P A S A + G L + +Q + + P +
Sbjct: 393 HS--LTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPAST 450
Query: 233 GRGGGPARECLGEACSSSGLPGPEPLEFQ-HPALAKFEDHEVGWLPETQPQGSMNLDSGS 291
P + L LP PL+ PA++ + Q S+ S
Sbjct: 451 PPDSPPLQAPLS-------LPASPPLQTSLSPAVSPLSSPLT--IHPLQALSSLASHSPQ 501
Query: 292 LKLGDAFRPASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKE 351
L P ++S+ + T P ++ +P A P PL P E
Sbjct: 502 APLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLA--PPPLQTASAPLTTPHLE 559
Query: 352 AAVMYPAELP-QSSPADSEQRVSETCIVPAWLPSLPDEV--FLEEAPLVRMRSPP-DPHA 407
PA P Q+ P+ ET P+ + + P + L PL + SPP P A
Sbjct: 560 TPPC-PAPCPLQAPPSPLTTPPPET---PSSIATPPPQAPPALASPPLQGLPSPPLSPLA 615
Query: 408 SQGPPASVHASDQPYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPT 467
+ P A + P P P + P S P
Sbjct: 616 TPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLL------QAPFSPPP 669
Query: 468 SHTPTGTANDNIPTIDPTGLTTNPPTAAESDL------LKPVPADALGLSGNDTPGPSHN 521
S P A + P P + PP+ A L + P P + +S + TP P
Sbjct: 670 S--PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 727
Query: 522 TALARGTGQ-PGSRPTWPSQCLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIPLA 580
LA Q P S P P + R+ P L P P P PP L + PLA
Sbjct: 728 PPLAAPPLQVPPSPPASPP--MSPSATPPPRVPPLLAAPPLQVP-PSPPASL--PMSPLA 782
Query: 581 EVRAAMRPACG----EAGEEAASTFEPGSYQFSFTQLLP----------------APREE 620
+ PA +A ++F PG FS + LP AP +
Sbjct: 783 KPPPQAPPALATPPLQALPSPPASF-PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 841
Query: 621 TRLENPATHPVLDQPCGQGLPAPNNSIQGKKVELA 655
PA+ P L P P P+ S+ G ++ LA
Sbjct: 842 VPPSPPAS-PTLQAPRRPPTPGPDTSVSGPRLTLA 875
Score = 36.6 bits (83), Expect = 0.10
Identities = 119/523 (22%), Positives = 161/523 (30%), Gaps = 121/523 (23%)
Query: 132 PSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPPATHPRSASLSH 191
P PP + AA R + GA V R+ L R A P + PR+
Sbjct: 35 PPPPVTPAALR--VLGAAGAVGRKP----------LAERAGGIGGATIPESAPRAGPTRS 82
Query: 192 PGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGG--------------- 236
G SR PA G R P A S PG+ R G
Sbjct: 83 AGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV 142
Query: 237 -------GPARECLG------------------------EACSSSGLPGPEPLEFQHP-- 263
P R L A + GLP P P P
Sbjct: 143 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 202
Query: 264 -----ALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRPASRSRSASGEVLGSWGGS 318
+++ +H E P +G G RPASRS S+S L S S
Sbjct: 203 EGPRKSVSSASEHST---TEPSPAARRRPSAG----GGLQRPASRSLSSSATPLSSPARS 255
Query: 319 GGTIPIVQAVPQGAETPRPLFQTKL---SRFLPQKEAA----VMYPAELPQSSPADSEQR 371
G + P P+P L P+K+AA + + L SP+ ++ R
Sbjct: 256 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKAR 315
Query: 372 V-----SETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQPYGTGL 426
+ +PA LP P PL +PP P A P S+ P T
Sbjct: 316 PVPPPDNAATPLPATLP--PSPPLATPLPL----APPSPSA----PPSLQTLPSPPATPP 365
Query: 427 GQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTP---------TGTAND 477
Q +T P P+ P + ++ P+ P T +
Sbjct: 366 SQAPPSMTTP---PMQAPPSLQTIPP----IQVPHSLTSPSLQAPPSPLALSSLQATTSL 418
Query: 478 NIPTIDPT-GLTTNPPTAAESDLLKP-----VPADALGLSG--NDTPGPSHNTALARGTG 529
PT+ T T P ++ L P P D+ L + P T+L+
Sbjct: 419 GSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVS 478
Query: 530 QPGSRPT-WPSQCLEELVQE--LARLDPSLCDPLASQPSPEPP 569
S T P Q L L A L + PL +Q S PP
Sbjct: 479 PLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPP 521
Score = 33.5 bits (75), Expect = 0.85
Identities = 38/137 (27%), Positives = 50/137 (36%), Gaps = 4/137 (2%)
Query: 72 PAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAAEAEAAAQA--V 129
P+PP + L T P P A Q P PL+ ATP A A A QA
Sbjct: 607 PSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 666
Query: 130 EPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPPATHPRSASL 189
PPSPP +A + S Q + P ++ P+ PA PP + +
Sbjct: 667 PPPSPPV-QAPFSPPASPPVSPSATPPS-QAPPSLAAPPLQVPPSPPASPPMSPSATPPP 724
Query: 190 SHPGGEGEPARSRAPAP 206
P P P+P
Sbjct: 725 QAPPPLAAPPLQVPPSP 741
Score = 32.0 bits (71), Expect = 2.5
Identities = 40/136 (29%), Positives = 54/136 (39%), Gaps = 19/136 (13%)
Query: 70 PGPAPPDAALCTSP-RPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAAEAEAAAQA 128
P +PP + T P + P++AA P P +P P++ ATP A A Q
Sbjct: 679 PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP-PMSPSATPPPQAPPPLAAPPLQV 737
Query: 129 VEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPPATHPRSAS 188
PPSPPAS T R ++ P VP PPA+ P S
Sbjct: 738 --PPSPPASPPMSPS-----------ATPPPRVPPLLAAPPL---QVPPSPPASLPMS-P 780
Query: 189 LSHPGGEGEPARSRAP 204
L+ P + PA + P
Sbjct: 781 LAKPPPQAPPALATPP 796
Score = 31.6 bits (70), Expect = 3.2
Identities = 28/111 (25%), Positives = 38/111 (34%), Gaps = 8/111 (7%)
Query: 70 PGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAAEAEAAAQAV 129
P APP ++P P + P P + P PL TP E ++
Sbjct: 539 PSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPL---TTP-----PPETPSSIATP 590
Query: 130 EPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPP 180
P +PPA + Q L L Q P + P+ PA PP
Sbjct: 591 PPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPP 641
>gi|122937241 SH3 and multiple ankyrin repeat domains 3 [Homo sapiens]
Length = 1747
Score = 47.4 bits (111), Expect = 6e-05
Identities = 119/509 (23%), Positives = 175/509 (34%), Gaps = 109/509 (21%)
Query: 76 DAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAAEAEAAAQAVEPPSPP 135
D+A + PRP AA +P P PGP + A L A +A A PS P
Sbjct: 913 DSAPESGDAPRPPPAATPPERPKRRPRPPGPDSPYAN--LGAFSASLFA-------PSKP 963
Query: 136 ASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPPATH--PRSASLSHPG 193
++R +++ E + +R L + P + P TH PR L +
Sbjct: 964 ------QRRKSPLVKQLQVEDAQERAALAVGSPGPGGGSFAREPSPTHRGPRPGGLDYGA 1017
Query: 194 GEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGG-----PARECLGEACS 248
G+G P P R L ++R F G ++ G P+R
Sbjct: 1018 GDGPGLAFGGPGPAKDRR--LEERRRSTVFLSVGAIEGSAPGADLPSLQPSRSIDERLLG 1075
Query: 249 SSGLPG-----PEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRPASR 303
+ G P P+ P ++ P P GS + + K D P +
Sbjct: 1076 TGPTAGRDLLLPSPVSALKPLVSG---------PSLGPSGSTFIHPLTGKPLDPSSPLAL 1126
Query: 304 SRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAELPQS 363
+ +A L S S P+ A+ P PLF +R + ++ PA P+S
Sbjct: 1127 ALAARERALASQAPSRSPTPVHSP---DADRPGPLFVDVQAR--DPERGSLASPAFSPRS 1181
Query: 364 SPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHA--------SQGPPAS- 414
PAW+P +P E+ P +SP D + S PA
Sbjct: 1182 ---------------PAWIP-VPARREAEKVPREERKSPEDKKSMILSVLDTSLQRPAGL 1225
Query: 415 --VHASDQPYGTGLGQRTGQVTVPTEYPLHECPGTAG-ADDCWQGVNGSVGISRPTSHTP 471
VHA T GQ ++ E E PGT A Q + + P + P
Sbjct: 1226 IVVHA------TSNGQEPSRLGGAEE----ERPGTPELAPAPMQSAAVAEPLPSPRAQPP 1275
Query: 472 TGTANDNIP---------------TIDPTGLTTNPPTAAESDL---LKPVPAD------- 506
GT D P + P L+++ E L P P +
Sbjct: 1276 GGTPADAGPGQGSSEEEPELVFAVNLPPAQLSSSDEETREELARIGLVPPPEEFANGVLL 1335
Query: 507 ALGLSGNDTPGPSHNTALARGTGQPGSRP 535
A L+G PGPS T + +G+P S P
Sbjct: 1336 ATPLAG---PGPSPTTVPSPASGKPSSEP 1361
Score = 32.7 bits (73), Expect = 1.5
Identities = 87/398 (21%), Positives = 133/398 (33%), Gaps = 56/398 (14%)
Query: 43 PEPRTQSPGTDLLPYLDWDYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPG 102
P P + P L Y D + +GGPGPA D L R R V G PG
Sbjct: 1001 PSPTHRGPRPGGLDYGAGDGPGLAFGGPGPA-KDRRL--EERRRSTVFLSVGAIEGSAPG 1057
Query: 103 TPGPLNRQATPLLYALAAEAEAAAQAVEPPSPPASRAAYRQRLQGAQRRVLRETSFQ--- 159
P + + + L A + + PSP +A + + G T
Sbjct: 1058 ADLPSLQPSRSIDERLLGTGPTAGRDLLLPSPV---SALKPLVSGPSLGPSGSTFIHPLT 1114
Query: 160 ------RKELRMSLPAR---LRPTVPARPPATHPRSASLSHPGGEGEPARSRAPAPGTAG 210
L ++L AR L P+R P T S PG ++R P G+
Sbjct: 1115 GKPLDPSSPLALALAARERALASQAPSRSP-TPVHSPDADRPGPLFVDVQARDPERGSLA 1173
Query: 211 RGPLANQQRKW----CFSEPGKLDRVGRGGGPARECLGEACSSSGLPGPEPLEFQHPALA 266
+ + W E K+ R R ++ + + + L P L H
Sbjct: 1174 SPAFSPRSPAWIPVPARREAEKVPREERKSPEDKKSMILSVLDTSLQRPAGLIVVHATSN 1233
Query: 267 KFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFR--PASRSRSASGEVLGSWGGSGGTIPI 324
E +G E +P G+ L ++ P+ R++ G + G G +
Sbjct: 1234 GQEPSRLGGAEEERP-GTPELAPAPMQSAAVAEPLPSPRAQPPGGTPADAGPGQGSS--- 1289
Query: 325 VQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAELPQSSPADSEQRVSETCIVPAWLPS 384
E P +F L PA+L SS ++ + ++ +VP
Sbjct: 1290 -------EEEPELVFAVNLP------------PAQL-SSSDEETREELARIGLVP----- 1324
Query: 385 LPDEVFLEEAPLVRMRSPPDPHASQGP-PASVHASDQP 421
P E F L + P P + P PAS S +P
Sbjct: 1325 -PPEEFANGVLLATPLAGPGPSPTTVPSPASGKPSSEP 1361
>gi|7662236 TSC22 domain family, member 2 [Homo sapiens]
Length = 780
Score = 47.4 bits (111), Expect = 6e-05
Identities = 81/320 (25%), Positives = 114/320 (35%), Gaps = 46/320 (14%)
Query: 295 GDAFRPASRSRSASGEVLGSWGGSGGTIPIVQAVPQGAETPR---PLFQTKLSRFLPQKE 351
GD R +S + + E G +GG++ +V A QGA P T +S+ P ++
Sbjct: 199 GDCIRHSS-TFDQTAERDSGLGATGGSVVVVVASMQGAHGPESGTDSSLTAVSQLPPSEK 257
Query: 352 AAVMYPAELPQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGP 411
+ PA+ PQS Q P + V APL PP P A+ GP
Sbjct: 258 MSQPTPAQ-PQSFSVGQPQPPP---------PPVGGAVAQSSAPL-----PPFPGAATGP 302
Query: 412 PASVHAS--DQPYGTGLGQRTGQVT-VPTEYPLHECPGTAGADDCWQGVNGSVGISRPTS 468
+ A+ QP G G G +T T V P P G + P +
Sbjct: 303 QPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGP-----------AVGAPAA 351
Query: 469 HTPTGTANDNIPTIDPTGLTTNPPTAAESDLLKPV-----PADALGLSGNDTPGPSHNTA 523
P A P I P L P+ L + V P+ A S P+
Sbjct: 352 QQPQQFAYPQ-PQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAAT 410
Query: 524 LARGTGQPGSRPTWPSQCLEELVQELARLDPSLCDPLASQPSPEPPLGLLDGLIPLAEVR 583
L GTGQ S + +Q + Q + P Q +P P G +P A V
Sbjct: 411 LPVGTGQNAS--SVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTG-----VPPATVG 463
Query: 584 AAMRPACGEAGEEAASTFEP 603
++P G AG + P
Sbjct: 464 GVVQPCLGPAGAGQPQSVPP 483
Score = 38.9 bits (89), Expect = 0.020
Identities = 82/373 (21%), Positives = 116/373 (31%), Gaps = 72/373 (19%)
Query: 72 PAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAAEAEAAAQAVEP 131
P PP T P+P A A S PQ GP + P L A+ A
Sbjct: 291 PLPPFPGAATGPQPMMAAAQPSQPQGA------GPGGQTLPPTNVTL---AQPAMSLPPQ 341
Query: 132 PSPPASRAAYRQRLQGAQRR-------VLRETSFQRKELRMSLPARLRPTVPARPPATHP 184
P P A +Q Q A + +L + E A L+P PA+P +T
Sbjct: 342 PGPAVGAPAAQQPQQFAYPQPQIPPGHLLPVQPSGQSEYLQQHVAGLQPPSPAQPSST-- 399
Query: 185 RSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPARECLG 244
G PA + GT Q S+P + + GPA+
Sbjct: 400 --------GAAASPATAATLPVGTGQNASSVGAQLMGASSQPS--EAMAPRTGPAQGGQV 449
Query: 245 EACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRPASRS 304
C +G+P P L + P++ P M
Sbjct: 450 APCQPTGVPPATVGGVVQPCLGPAGAGQ----PQSVPPPQM------------------- 486
Query: 305 RSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAELPQSS 364
SG + GG +P V VP P + S +P A + +L +
Sbjct: 487 -GGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAPLAQSQQLSSHT 545
Query: 365 PADSEQRVSE---------TCIVPAWLPSLPDEVF-LEEAPLV------RMRSPPDPHAS 408
P + + T P LP F + PLV R +S P P
Sbjct: 546 PVSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDDTRRKSEPLPQ-- 603
Query: 409 QGPPASVHASDQP 421
PP S+ A ++P
Sbjct: 604 --PPLSLIAENKP 614
Score = 34.3 bits (77), Expect = 0.50
Identities = 101/447 (22%), Positives = 156/447 (34%), Gaps = 91/447 (20%)
Query: 316 GGSGGTIPIVQAV----PQGA--------ETPRPLFQTKLSRFLPQKEAAVMYPAELPQS 363
G + G P++ A PQGA T L Q +S PQ AV PA
Sbjct: 297 GAATGPQPMMAAAQPSQPQGAGPGGQTLPPTNVTLAQPAMS-LPPQPGPAVGAPAAQQPQ 355
Query: 364 SPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQPYG 423
A + ++ ++P PS E + ++ SP P ++ + A+ P G
Sbjct: 356 QFAYPQPQIPPGHLLPVQ-PSGQSEYLQQHVAGLQPPSPAQPSSTGAAASPATAATLPVG 414
Query: 424 TG--------------------LGQRTGQVT-------VPTEYP-------LHECPGTAG 449
TG + RTG PT P + C G AG
Sbjct: 415 TGQNASSVGAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAG 474
Query: 450 ADDCWQGVNGSVGISRPTSHTPTGT-----ANDNIPTIDPTGLTTNPPTAAESDLLKPVP 504
A +G S P S P G N+P P + T + + P P
Sbjct: 475 AGQPQSVPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVTMPNVPAP 534
Query: 505 ADALGLSGNDTPGPSHNTALARGTGQP-----GSRPT-WPSQCLEELVQELARLDPSLCD 558
+ TP S ++++ + G P S PT P L + + L + D
Sbjct: 535 LAQSQQLSSHTP-VSRSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQTQPLVGQVDD 593
Query: 559 PLA-SQPSPEPPLGLLDGLIPLAEVRAAMRPACGEAGEEAASTFEPGSYQFS-FTQLLPA 616
S+P P+PPL L +AE + ++P ++ S S F+ +P
Sbjct: 594 TRRKSEPLPQPPLSL------IAENKPVVKPPVADSLANPLQLTPMNSLATSVFSIAIPV 647
Query: 617 PREETRLENPAT--------------HPVLDQPCGQGLPAPNNSIQGKKVELAARLQK-- 660
+E R NP+T + D G G+ A +N K+E A L K
Sbjct: 648 DGDEDR--NPSTAFYQAFHLNTLKESKSLWDSASGGGVVAIDN-----KIEQAMDLVKSH 700
Query: 661 MLQDLHTEQERLQGEAQAWARRQAALE 687
++ + E E L+ + + R + LE
Sbjct: 701 LMYAVREEVEVLKEQIKELVERNSLLE 727
Score = 31.2 bits (69), Expect = 4.2
Identities = 82/372 (22%), Positives = 125/372 (33%), Gaps = 56/372 (15%)
Query: 181 ATHPRSASLSHPGGE---------GEPARSRAPAPGTAGRGPLANQQRKWCFSE----PG 227
A P + PGG+ +PA S P PG A P A Q +++ + + PG
Sbjct: 308 AAQPSQPQGAGPGGQTLPPTNVTLAQPAMSLPPQPGPAVGAPAAQQPQQFAYPQPQIPPG 367
Query: 228 KLDRVGRGGGPARECLGEACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMNL 287
L V G E L + +GL P P + A LP Q + ++
Sbjct: 368 HLLPVQPSG--QSEYLQQ--HVAGLQPPSPAQPSSTGAAA-SPATAATLPVGTGQNASSV 422
Query: 288 DSGSLKLGDAFRPASRSRSASGEVLGSW-----------GGSGGTI-----PIVQAVPQG 331
G+ +G + +P+ +G G GG + P PQ
Sbjct: 423 --GAQLMGASSQPSEAMAPRTGPAQGGQVAPCQPTGVPPATVGGVVQPCLGPAGAGQPQS 480
Query: 332 AETPRPLFQTKLSRFLPQKEAAVMYPAELPQSSPADSEQRVSETCIVPAWLPSLPDEVFL 391
P+ LS A V +P + PA S VS T + +P++P
Sbjct: 481 VPPPQMGGSGPLSAVPGGPHAVVPGVPNVPAAVPAPSVPSVSTTSVT---MPNVP----- 532
Query: 392 EEAPLVRMRSPPDPHASQGPPASVHASDQPYGTGLGQRTGQVTVPTEYPLHECPGTAGAD 451
APL + + S P S +S GL G + PT P +
Sbjct: 533 --APLAQSQ-----QLSSHTPVS-RSSSIIQHVGLPLAPGTHSAPTSLPQSDLSQFQTQT 584
Query: 452 DCWQG-VNGSVGISRPTSHTPTGTANDNIPTIDP---TGLTTNPPTAAESDLLKPVPADA 507
G V+ + S P P +N P + P L + L V + A
Sbjct: 585 QPLVGQVDDTRRKSEPLPQPPLSLIAENKPVVKPPVADSLANPLQLTPMNSLATSVFSIA 644
Query: 508 LGLSGNDTPGPS 519
+ + G++ PS
Sbjct: 645 IPVDGDEDRNPS 656
>gi|38683860 insulin receptor substrate 2 [Homo sapiens]
Length = 1338
Score = 46.6 bits (109), Expect = 1e-04
Identities = 81/287 (28%), Positives = 96/287 (33%), Gaps = 89/287 (31%)
Query: 6 PGGDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLDWDYVRV 65
PG P S L LS A S Y P P + SP + L P
Sbjct: 991 PGAPSGHPVGSLDGL----LSPEASSPYPPLP-----PRP-SASPSSSLQP--------- 1031
Query: 66 VWGGPGPAP-------PDAALCTSPRPRPAVA------------------ARSGPQPTEV 100
P PAP P +A+ T+ P A + A + PQP
Sbjct: 1032 --PPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAA 1089
Query: 101 PGTPGPLNRQATPL-------LYALAAEAEAAAQAVEPPSPPASRAAYRQRLQGAQRRVL 153
P P R A+P L + EA QA +PP P R QG +RR
Sbjct: 1090 PPKPEAA-RVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHS 1148
Query: 154 RETSFQRKELRMSLPARLRPTVP--ARPPATHPRSASLSH--------------PGGEGE 197
ET S + P P A P H SAS+ + PGG E
Sbjct: 1149 SET--------FSSTTTVTPVSPSFAHNPKRH-NSASVENVSLRKSSEGGVGVGPGGGDE 1199
Query: 198 P---ARSRAPAPGTAGRGPLANQQRKWCFSEPGKL-DRVGRGGGPAR 240
P R PAP PLA Q R W +PG L G GG P R
Sbjct: 1200 PPTSPRQLQPAP------PLAPQGRPWTPGQPGGLVGCPGSGGSPMR 1240
Score = 30.4 bits (67), Expect = 7.2
Identities = 48/187 (25%), Positives = 58/187 (31%), Gaps = 43/187 (22%)
Query: 73 APPDAALCTSPRPRPAV---------AARSGPQPTEVPGTPGPLNRQATPLLYALAAEAE 123
A P AA C+S R R A AA +G +P V G+P PL +
Sbjct: 349 ATPPAAKCSSCRVRTASEGDGGAAAGAAAAGARPVSVAGSPLSPGPVRAPLSRSHTLSGG 408
Query: 124 AAAQAVEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPPATH 183
+ + PA A R MS+P P P AT
Sbjct: 409 CGGRGSKVALLPAGGALQHSR-------------------SMSMPVAHSP-----PAATS 444
Query: 184 PRSASLSHPGGEGE---PARSRAPAPGTAGRGP-----LANQQRKWCFSEPG--KLDRVG 233
P S S S G G P P P GP + S+PG LD G
Sbjct: 445 PGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQRPSSGSASASGSPSDPGFMSLDEYG 504
Query: 234 RGGGPAR 240
G R
Sbjct: 505 SSPGDLR 511
>gi|24308326 BR serine/threonine kinase 1 [Homo sapiens]
Length = 778
Score = 46.2 bits (108), Expect = 1e-04
Identities = 51/190 (26%), Positives = 70/190 (36%), Gaps = 15/190 (7%)
Query: 8 GDRASPASSTSSLDLWHLSMRADSAYSSFSAASGGPEPRTQSPGTDLLPYLD-WDYVRVV 66
G SP + +L++ S R+ S + + S P +SP P D R
Sbjct: 409 GGGGSPVPTRRALEMAQHSQRSRSVSGASTGLSSSPLSSPRSPVFSFSPEPGAGDEAR-- 466
Query: 67 WGGPGPAPPDAALCTSPRPRPAVAARSGPQP----TEVPGTPG-PLNRQATPL---LYAL 118
GG P L S PR A P P T +PG PG P + TPL L+
Sbjct: 467 -GGGSPTSKTQTL-PSRGPRGGGAGEQPPPPSARSTPLPGPPGSPRSSGGTPLHSPLHTP 524
Query: 119 AAEAEAAAQAVEPPSPPAS--RAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVP 176
A PPSP AA+R RL + L F R+++++ + P
Sbjct: 525 RASPTGTPGTTPPPSPGGGVGGAAWRSRLNSIRNSFLGSPRFHRRKMQVPTAEEMSSLTP 584
Query: 177 ARPPATHPRS 186
P RS
Sbjct: 585 ESSPELAKRS 594
>gi|16262452 cingulin [Homo sapiens]
Length = 1203
Score = 45.4 bits (106), Expect = 2e-04
Identities = 55/183 (30%), Positives = 83/183 (45%), Gaps = 24/183 (13%)
Query: 657 RLQKMLQDLHTEQERL-------QGEAQAWARRQAALEAAVRQACAPQELERFSRFMADL 709
+LQK LQ L + E + EA +R+AA+E +R+ +E + F R + L
Sbjct: 685 QLQKTLQQLRQDCEEASKAKMVAEAEATVLGQRRAAVETTLRET--QEENDEFRRRILGL 742
Query: 710 ERVL----GLLLLLGSRLARVRRALARAASDSDPDEQRLRLLQRQEEDAKELKEHV-ARR 764
E+ L GL+ + AR+R L R ++ E+ L Q +E K + AR
Sbjct: 743 EQQLKETRGLVDGGEAVEARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARL 802
Query: 765 ERAVR---------EVLVRALPVEELRVYCALLAGKAAVLAQQRNLDERIRLLQDQLDAI 815
E A R + L RAL EE + L GKA + Q+R LD + L +L+ I
Sbjct: 803 EEAQRGLARLGQEQQTLNRALE-EEGKQREVLRRGKAELEEQKRLLDRTVDRLNKELEKI 861
Query: 816 RDD 818
+D
Sbjct: 862 GED 864
Score = 30.4 bits (67), Expect = 7.2
Identities = 41/146 (28%), Positives = 66/146 (45%), Gaps = 29/146 (19%)
Query: 649 GKKVELAARLQKMLQDLHTEQERL-------QGEAQAWARRQAALEAAVRQ-----ACAP 696
G+ VE ARL+ LQ L E+++L Q E + A + ALEA + + A
Sbjct: 756 GEAVE--ARLRDKLQRLEAEKQQLEEALNASQEEEGSLAAAKRALEARLEEAQRGLARLG 813
Query: 697 QELERFSRFMADLERVLGLL-----------LLLGSRLARVRRALARAASDSDPDEQRLR 745
QE + +R + + + +L LL + R+ + L + DS +Q L+
Sbjct: 814 QEQQTLNRALEEEGKQREVLRRGKAELEEQKRLLDRTVDRLNKELEKIGEDS---KQALQ 870
Query: 746 LLQRQEEDAKE-LKEHVARRERAVRE 770
LQ Q ED KE + VA +R ++
Sbjct: 871 QLQAQLEDYKEKARREVADAQRQAKD 896
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 45.1 bits (105), Expect = 3e-04
Identities = 56/230 (24%), Positives = 80/230 (34%), Gaps = 50/230 (21%)
Query: 72 PAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQ--------ATPLLYALAAEAE 123
P+PP SP P P R P P TP P R+ + P+ +
Sbjct: 550 PSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPP 609
Query: 124 AAAQAVEPPSPPASRAA--------------YRQRLQGAQRRVLRETSFQRKELRMSLPA 169
+ PP PP RA+ +QR +R R S K + S P+
Sbjct: 610 PKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKR--RSPSLSSKHRKGSSPS 667
Query: 170 RLRPTVPARPPATHPRSASLSHP--------------GGEGEPARSRAPAPGTAGRGPLA 215
R T AR P + R + P G P R ++P+P T P+
Sbjct: 668 --RSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTR---PIR 722
Query: 216 NQQRKWCFSEPGKLDRVGRGGGPARECLGEACSSSGLPG-PEPLEFQHPA 264
R EP K + + P+ + + SS + G PEP + PA
Sbjct: 723 RVSRT---PEPKK---IKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPA 766
Score = 30.0 bits (66), Expect = 9.4
Identities = 30/103 (29%), Positives = 42/103 (40%), Gaps = 13/103 (12%)
Query: 39 ASGGPEPRTQSPGTDLLPYLDWDYVRVVWGGPGPAPPDAALCTSPRP-RPAVAARS---G 94
AS P+ R QSP P +R V P P A SP+ R ++RS
Sbjct: 704 ASSSPQ-RRQSPSPSTRP------IRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGS 756
Query: 95 PQPT--EVPGTPGPLNRQATPLLYALAAEAEAAAQAVEPPSPP 135
P+P + P P P+ Q+ ++ A + A PSPP
Sbjct: 757 PEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPP 799
>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
Length = 2161
Score = 44.3 bits (103), Expect = 5e-04
Identities = 105/448 (23%), Positives = 154/448 (34%), Gaps = 92/448 (20%)
Query: 68 GGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAAEAEAAAQ 127
G P PP AL P+P++ G P+ PG P P + + + A +
Sbjct: 1030 GSPDDPPPRLAL----GPQPSLRGWRGGGPSPTPGAPSPSHHGSAG--GGGGSSQGPALR 1083
Query: 128 AVEPPSPPASRAAYRQRLQGAQRR--VLRETSFQRKELR-MSLPARLRPTVPARPPATHP 184
+ P AS A Y G R+ ++++T + + + LP PT PA P P
Sbjct: 1084 YFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPP-P 1142
Query: 185 RSASLSHPGGEGEPA-RSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGG------ 237
A+ S P +AP+ ++GR ++Q P + + G GGG
Sbjct: 1143 AVAAPSEKNSIPIPTIIIKAPSTSSSGR---SSQGSSTEAEPPTQPEPTGGGGGGGSSPS 1199
Query: 238 PARECLGEACSSSGLP------GPEPLEFQH---PALAKFEDHEVGWLPETQPQGSMNL- 287
PA S S +P GP L+F AL E GW E + + ++ L
Sbjct: 1200 PAPAMSPVPPSPSPVPTPASPSGPATLDFTSQFGAALVGAARREGGWQNEARRRSTLFLS 1259
Query: 288 ------DSGSLKLGDAFRPASRSR--------------------SASGEVLG-------S 314
D G LG P R R + SG G +
Sbjct: 1260 TDAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGSRA 1319
Query: 315 WGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAELPQSSPADSEQRVSE 374
+GG GG+ +P PRPL + L P L ++ + + SE
Sbjct: 1320 YGGGGGSSAFTSFLP-----PRPLVHPLTGKALDPAS-----PLGLALAARERALKESSE 1369
Query: 375 TCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGPPASVHASDQP--------YGTGL 426
P P P + P S PHA P + + P Y GL
Sbjct: 1370 GGGAPQPPPRPPSPRYEAPPPTPHHHS---PHAHHEPVLRLWGASPPDPARRELGYRAGL 1426
Query: 427 GQRTGQVTVPTEYP------LHECPGTA 448
G + + ++P P LH P TA
Sbjct: 1427 GSQ--EKSLPASPPAARRSLLHRLPPTA 1452
Score = 31.6 bits (70), Expect = 3.2
Identities = 50/217 (23%), Positives = 69/217 (31%), Gaps = 59/217 (27%)
Query: 42 GPEPRTQSPGTDLLPYLDWDYVRVVWGGPGPAPPD-----AALCTSPRPRPAVAARSGPQ 96
G EP PG V W P P+ + +PR V + GP
Sbjct: 1463 GTEPPAPHPG-----------VSKPWRSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPP 1511
Query: 97 PTEVPGTPGPLNRQATP--LLYALAAEAEAAAQAVEPPSPPASRAAYRQRL--QGAQRRV 152
+ PG P P R++ P A+E V PP P+ + L + +
Sbjct: 1512 SEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPL 1571
Query: 153 LRETSFQRKELRMS----------------LPARLRPTVPARPPATHPRSASLS------ 190
SF++ E ++ LP P V A PP ++SL+
Sbjct: 1572 EFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEV 1631
Query: 191 --------------HPGGEGEPARSRAPAPGTAGRGP 213
HP G PA APAP GP
Sbjct: 1632 ATLTQGASAAPGDPHPPGPPAPA---APAPAAPQPGP 1665
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 43.9 bits (102), Expect = 6e-04
Identities = 85/317 (26%), Positives = 111/317 (35%), Gaps = 69/317 (21%)
Query: 334 TPRPLFQTKLSRFLPQKEAAVMYPAE-LPQSSPADSEQRVSETCIVPAWLPSLPDEVFLE 392
+PRP + P E ++P P SP E +SE P L LP+E+ L
Sbjct: 861 SPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPP--LSPLPEELPLS 918
Query: 393 ---EAPLVRMRSPPDPHASQGPPAS--VHASDQPYGTGLGQRTGQVTVPTEYPLHECPGT 447
E L PPDP PP S + A+ P + LG+ EYP G
Sbjct: 919 PSGEPSLSPQLMPPDPLP---PPLSPIITAAAPPALSPLGE--------LEYPF----GA 963
Query: 448 AGADDCWQGVNGSVGISRPTSHTPTGTANDNIPTIDPTGLTTNPPTAAESDLLKPVPADA 507
G D ++ P TP +PP A +PVP
Sbjct: 964 KGDSD------PESPLAAPILETPI-----------------SPPPEANCTDPEPVPPMI 1000
Query: 508 LGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQCLEELVQELARLD--PSLCDPLA---S 562
L S GP+ P P QC L L + PS C P A S
Sbjct: 1001 LPPSPGSPVGPA----------SPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLS 1050
Query: 563 QPSPEPPLGLLDGLIPLAEVRAAMRPACGEAGEEAASTFEPGSYQFSFTQLLPAPREETR 622
PSP P+G + G+ AE+ E E S E + + S T LP+P +
Sbjct: 1051 VPSPLSPIGKVVGVSDEAELH--------EMETEKVSEPECPALEPSATSPLPSPMGDLS 1102
Query: 623 LENPATHPVLDQPCGQG 639
P+ P LD G G
Sbjct: 1103 CPAPSPAPALDDFSGLG 1119
Score = 40.8 bits (94), Expect = 0.005
Identities = 112/487 (22%), Positives = 151/487 (31%), Gaps = 110/487 (22%)
Query: 193 GGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRG-------GGPARECLGE 245
G + P S PGT G G L++ + E K++ G + LG
Sbjct: 1850 GVKASPVPSDPEKPGTPGEGMLSSDLDRISTEELPKMESKDLQQLFKDVLGSEREQHLG- 1908
Query: 246 ACSSSGLPGPEPLEFQHPALAKFEDHEVGWLPETQPQGSMN-------LDSGSLKLGDAF 298
C + GL G Q P L +G LP + P S LDS + G F
Sbjct: 1909 -CGTPGLEGSRT-PLQRPFLQG--GLPLGNLPSSSPMDSYPGLCQSPFLDSR--ERGGFF 1962
Query: 299 RPASRSRSASGEVLGSWGGSGGTIPIVQAVP--QGAETPRPLFQTKLSRFLPQKE----- 351
P GE W GSGGT P P +G Q L R+ +E
Sbjct: 1963 SPEP------GEPDSPWTGSGGTTPSTPTTPTTEGEGDGLSYNQRSLQRWEKDEELGQLS 2016
Query: 352 -------AAVMYPAELPQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEA---------- 394
A + +P L Q P D R + + +P+ +L++A
Sbjct: 2017 TISPVLYANINFP-NLKQDYP-DWSSRCKQIMKLWRKVPAADKAPYLQKAKDNRAAHRIN 2074
Query: 395 -------------------------PLVRMRSPPDPHASQGPP----ASVHASDQPYGTG 425
P + +R PP P A PP ++ G
Sbjct: 2075 KVQKQAESQINKQTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAG 2134
Query: 426 LGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTPTGTA-----NDNIP 480
L P P PG + + + V P S P G A P
Sbjct: 2135 LSTSADGFLKP---PAGSVPGPDSPGELFLKLPPQVPAQVP-SQDPFGLAPAYPLEPRFP 2190
Query: 481 TIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQ 540
T PT PT A + +P A G PG H T G P +P+ P
Sbjct: 2191 TAPPTYPPYPSPTGAPA---QPPMLGASSRPGAGQPGEFHTTP----PGTPRHQPSTPDP 2243
Query: 541 CLEELVQELARL----DPSLCDPLASQPSPEPPLGLLDGLIPLAEVRAAMRPACGEAGEE 596
L+ L L P + AS+P PP P E R A+ E G
Sbjct: 2244 FLKPRCPSLDNLAVPESPGVGGGKASEPLLSPP--------PFGESRKALEVKKEELGAS 2295
Query: 597 AASTFEP 603
+ S P
Sbjct: 2296 SPSYGPP 2302
Score = 40.0 bits (92), Expect = 0.009
Identities = 128/562 (22%), Positives = 188/562 (33%), Gaps = 95/562 (16%)
Query: 44 EPRTQSPGTDLLPYLDWDYVRVVWGGPGPAPPDAALCT----SPRPRPAVAARSGPQPTE 99
EP+ ++P + +P L P P ++ L SP P A+R P P E
Sbjct: 427 EPQLEAPLNEEMPLL-------------PPPEESPLSPPPEESPTSPPPEASRLSPPPEE 473
Query: 100 VPGTPGPLNRQATPLLYALAAEAEAAAQAVEPPSPPASRAAYRQRLQGAQRRVLRETSFQ 159
+P +P P +A L L + P SPP + + L E+
Sbjct: 474 LPASPLP---EALHLSRPLEESPLSPPPEESPLSPPPESSPFSP---------LEESPLS 521
Query: 160 RKELRMSLPARLRPTVPARPPATHPRSASLSHPGGEGEPARSRAPAPGTAGR-------G 212
E PA P P PP P S P P A R
Sbjct: 522 PPEESPPSPALETPLSP--PPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEES 579
Query: 213 PLANQQRKWCFSEPGKLDRVGRGGGPAREC-LGEACSSSGL-PGPEPLEFQHPALAKFED 270
P++ + S P + R+ P E L S L P PE P ED
Sbjct: 580 PMSPPPEESPMSPPPEASRL---FPPFEESPLSPPPEESPLSPPPEASRLSPPP----ED 632
Query: 271 HEVGWLPETQPQGSMNLDSGSLKLGDAFRPASRSRSASGEVLGSWGGSGGTIPIVQAVPQ 330
+ PE P P SR + V+ P+ P+
Sbjct: 633 SPMSPPPEESPMSP---------------PPEVSRLSPLPVVSRLSPPPEESPL-SPPPE 676
Query: 331 GAETPRPLFQTKLSRFLPQKEAAVMYPAELPQSSPADSEQRVS----ETCIVPAWLPSLP 386
+ T P ++LS P +++ P E +SP + +S E+ ++P LP P
Sbjct: 677 ESPTSPPPEASRLSP--PPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLP--LPEEP 732
Query: 387 DEVFLEEAPLVRMRSPPDPHASQGP--PASVHASDQPYGTGLGQRTGQVTVPTEYPLHEC 444
E P + R P +PH S P P +++P+ + + VP E H
Sbjct: 733 QLCPRSEGPHLSPR-PEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEE--PHLS 789
Query: 445 PGTAGADDCWQGVNGSVGISRPTSHTPTGTANDNIPTIDPTGLTTNPPTAAESDLLKPVP 504
P G Q + P + P + P + P ++ +E L P P
Sbjct: 790 PQAEGPHLSPQPEELHLS---PQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRP 846
Query: 505 ADALGLSGNDTPGPSHNTALARGTGQPGSRPTWPSQC--LEEL----VQELARLDPSLCD 558
++ + P S +P P P QC EEL L P L +
Sbjct: 847 EESHLSPELEKPPLS---------PRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGE 897
Query: 559 PLASQPSPEPPLGLLDGLIPLA 580
P S+P EPPL L +PL+
Sbjct: 898 PALSEPG-EPPLSPLPEELPLS 918
Score = 34.3 bits (77), Expect = 0.50
Identities = 21/68 (30%), Positives = 27/68 (39%), Gaps = 3/68 (4%)
Query: 73 APPDAALCTSPRPRPAVAARSGPQPTEVPGTP---GPLNRQATPLLYALAAEAEAAAQAV 129
+PP A CT P P P + P P +P PL Q +PLL +
Sbjct: 983 SPPPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQC 1042
Query: 130 EPPSPPAS 137
PP+ P S
Sbjct: 1043 SPPALPLS 1050
Score = 30.0 bits (66), Expect = 9.4
Identities = 54/232 (23%), Positives = 79/232 (34%), Gaps = 45/232 (19%)
Query: 70 PGPAPPDAALCTSPRPRPA------VAARSGPQPTEVPGTPGPLNRQATPLLYALAAEAE 123
P P PP++ PR P+ A+ ++ P TP PL+ +A + +
Sbjct: 2387 PQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAF-CPSPVTPRFQ 2445
Query: 124 AAAQAVEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELR----------MSLPA---- 169
+ PPS P SR + L R E +F+ L +LPA
Sbjct: 2446 SPDPYSRPPSRPQSRDPFAP-LHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAG 2504
Query: 170 RLRPTVPARPPATHPRSAS------------LSHPGGEGEPA-RSRAPAPGTA------- 209
L VP+ P RS + P GEP+ + P PG
Sbjct: 2505 ELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINS 2564
Query: 210 --GRGPLANQQRKWCFS-EPGKLDRVGRGGGPARECLGEACSSSGLPGPEPL 258
G GP + + ++ G G GP+ GE+ S L P L
Sbjct: 2565 HFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVL 2616
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 43.5 bits (101), Expect = 8e-04
Identities = 107/445 (24%), Positives = 134/445 (30%), Gaps = 100/445 (22%)
Query: 69 GPGPAPP-DAALCTSPRPRPAVAARSGPQPTEVPGTPGPLNRQATPLLYALAAEAEAAAQ 127
G GPA P + A +P P PA AR G + PG P P R P A A AA+
Sbjct: 72 GAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSP-RRPLVP-----AGPAPPAAK 125
Query: 128 AVEPPSPPASRAAYRQRLQGAQRRVLRETSFQRKELRMSLPARLRPTVPARPPATHPRSA 187
PP A A P V A P P A
Sbjct: 126 LRPPPEGSAGSCA---------------------------PVPAAAAVAAGP---EPAPA 155
Query: 188 SLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPARECLGEAC 247
+ P G A P PG G GP G G GP + A
Sbjct: 156 GPAKPAGPAALAARAGPGPG-PGPGP-------------------GPGPGPGKPAGPGAA 195
Query: 248 SSSGLPGPEPLEFQH----PALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRPASR 303
+ L G L H PA++ + LP +P + +G A PA
Sbjct: 196 QT--LNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPA 253
Query: 304 SRSASGEVLGSWGGSGGTIPIVQAVPQGAETPRPLFQTKLSRFLPQKEAAVMYPAELPQS 363
+ S A P A P P L+R P A P P
Sbjct: 254 APSPPAAP-------------APAAPAAAPPPPPPAPATLAR-PPGHPAGP--PTAAPAV 297
Query: 364 SPADSEQRVSETCIVPAWLPSL-----------PDEVFLEEAPLVRMRSPPDPHASQGPP 412
P + Q PA P+ P AP V+ SP + P
Sbjct: 298 PPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPA 357
Query: 413 ASVHASDQPYGTGLGQ-----RTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPT 467
A A+ P T G + P P PGT +G G+V ++
Sbjct: 358 AQTLAASGPASTAASMVIGPTMQGALPSPAAVP-PPAPGT--PTGLPKGAAGAV--TQSL 412
Query: 468 SHTPTGTANDNIPTIDPTGLTTNPP 492
S TPT T + T+ PT L P
Sbjct: 413 SRTPTATTSGIRATLTPTVLAPRLP 437
Score = 38.1 bits (87), Expect = 0.035
Identities = 62/215 (28%), Positives = 72/215 (33%), Gaps = 45/215 (20%)
Query: 68 GGPGPAPPDAALCTSPRPRP----------AVAARSGPQPTEVPGT-PG-----PLNRQA 111
G P P AA+ P P P A+AAR+GP P PG PG P A
Sbjct: 135 GSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGA 194
Query: 112 TPLLYALAA-----EAEAAAQAVEPPSPPASRAAYRQRLQGA--QRRVLRETSFQRKELR 164
L AA A A A ++ P A + G Q +
Sbjct: 195 AQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAA 254
Query: 165 MSLPARLRPTVP-ARPPATHPRSASLSHPGGE--GEPARSRA-PAPGTAGRGPLANQQRK 220
S PA P P A PP P A+L+ P G G P + A P P A G A
Sbjct: 255 PSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSA----- 309
Query: 221 WCFSEPGKLDRVGRGGGPARECLGEACSSSGLPGP 255
G PA G A SG PGP
Sbjct: 310 ------------GAAPAPAPAAGGPA-GVSGQPGP 331
Score = 37.0 bits (84), Expect = 0.077
Identities = 111/490 (22%), Positives = 144/490 (29%), Gaps = 122/490 (24%)
Query: 184 PRSASLSHPGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLDRVGRGGGPARECL 243
P A+ + P E A AP P AGR + PG GGGP R
Sbjct: 67 PAGAAGAGPAAPAEGAPGAAPEPPPAGR------------ARPG-------GGGPQR--- 104
Query: 244 GEACSSSGLPGP-EPLEFQHPA--LAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDAFRP 300
G P P PL PA AK G P + + ++ G P
Sbjct: 105 ------PGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPA----AAAVAAGPEPAP 154
Query: 301 ASRSRSASGEVLGSWGGSG---------GTIPIVQAVPQGAETPRPLFQTKLSRFLPQKE 351
A ++ A L + G G G P A P A+T S L
Sbjct: 155 AGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQT------LNGSAALLNSH 208
Query: 352 AAVMYPAELPQSSPADSEQRVSETCIVPAWLPSLPDEVFLEEAPLVRMRSPPDPHASQGP 411
A L + PA ++P P+ P V ++ P V +PP P A P
Sbjct: 209 HAAAPAVSLVNNGPA---------ALLPLPKPAAPGTV-IQTPPFVGAAAPPAPAAPSPP 258
Query: 412 PASVHASDQPYGTGLGQRTGQVTVPTEYPLHECPGTAGADDCWQGVNGSVGISRPTSHTP 471
A A+ P P P A ++RP H P
Sbjct: 259 AAPAPAA-----------------PAAAPPPPPPAPA-------------TLARPPGH-P 287
Query: 472 TGTANDNIPTIDPTGLTTNPPTAAESDLLKPVPADALGLSGNDTPGPSHNTALARGTGQP 531
G P + P N +A + P G+SG PG + A A G
Sbjct: 288 AGPPT-AAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAA---AAAPAPGVK 343
Query: 532 GSRPTWPSQCLEELVQELARLDP---------------SLCDPLA-SQPSPEPPLGLLDG 575
P Q Q LA P +L P A P+P P GL G
Sbjct: 344 AESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKG 403
Query: 576 LIPLAEVRAAMRPACGEAGEEAASTFEPGSYQFSFTQLLPAPREETRLENPATHPVLDQP 635
+ P +G A + T + APR +NP P
Sbjct: 404 AAGAVTQSLSRTPTATTSGIRA-----------TLTPTVLAPRLPQPPQNPTNIQNFQLP 452
Query: 636 CGQGLPAPNN 645
G L N
Sbjct: 453 PGMVLVRSEN 462
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 43.5 bits (101), Expect = 8e-04
Identities = 113/432 (26%), Positives = 150/432 (34%), Gaps = 63/432 (14%)
Query: 43 PEPRTQSPGTDLLPYLDWDYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPG 102
P+ SP P W + + GP PPD PRP+ + S P PTE
Sbjct: 677 PQGSPSSPAPGPPPGAPWAFSYLA--GPPATPPDP-----PRPKRRSHSLSRPGPTEGDA 729
Query: 103 ---TPGPLNRQATPLLYALAAEAEAAAQAVEP-PSPPASRAAYRQRLQGAQRRVLRETSF 158
GP+ +T YA + V PS + A R Q R R+
Sbjct: 730 EGEAEGPVG--STLGSYATLTRRPGRSALVRTSPSVTPTPARGTPRSQSFALRARRKGPP 787
Query: 159 QRKELRMSLPARLRPTVPA-------RPPATHPRSASLSHPGGEGEPARSRAPAPGTAGR 211
R+S + P P + AT PR +LS P G EP APA
Sbjct: 788 PPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPA------ 841
Query: 212 GPLANQQRKWCFSEPGKLDRVGRGGGPARECLGEACSSSGLPGPEPLEF---QHPALAKF 268
GP ++ + + EPG G P+R GE GLP E Q P A
Sbjct: 842 GPASDTEEE----EPGP-----EGTPPSRGSSGE-----GLPFAEEGNLTIKQRPKPAGP 887
Query: 269 EDHEVGWLPETQPQGSMNL-DSGSLKLGDAFRPASRSRSASGEVLGSWGGSGGTIPIVQA 327
E P NL +S ++K RP R R L ++G + T A
Sbjct: 888 PPRET----PVPPGLDFNLTESDTVKR----RPKCREREPLQTALLAFGVASATPG--PA 937
Query: 328 VPQGAETPRPLFQTKLSRFLPQKEAAVMYPAELPQS-SPADSEQRVSETCIVPAWLPSLP 386
P + TP ++ + LPQ E + + +P +P+ + Q C P S
Sbjct: 938 APLPSPTPG---ESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLESSAA 994
Query: 387 DEVFLE-EAPLVRMRSPPDPHASQGP-PASVHASDQPY-GTGLGQRTGQVTVPTEYPLHE 443
E E P P A P P SV + + G L R G VP P E
Sbjct: 995 SRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAPRLGPRPVPPPRP--E 1052
Query: 444 CPGTAGADDCWQ 455
GT G Q
Sbjct: 1053 STGTVGPGQAQQ 1064
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 43.5 bits (101), Expect = 8e-04
Identities = 113/432 (26%), Positives = 150/432 (34%), Gaps = 63/432 (14%)
Query: 43 PEPRTQSPGTDLLPYLDWDYVRVVWGGPGPAPPDAALCTSPRPRPAVAARSGPQPTEVPG 102
P+ SP P W + + GP PPD PRP+ + S P PTE
Sbjct: 759 PQGSPSSPAPGPPPGAPWAFSYLA--GPPATPPDP-----PRPKRRSHSLSRPGPTEGDA 811
Query: 103 ---TPGPLNRQATPLLYALAAEAEAAAQAVEP-PSPPASRAAYRQRLQGAQRRVLRETSF 158
GP+ +T YA + V PS + A R Q R R+
Sbjct: 812 EGEAEGPVG--STLGSYATLTRRPGRSALVRTSPSVTPTPARGTPRSQSFALRARRKGPP 869
Query: 159 QRKELRMSLPARLRPTVPA-------RPPATHPRSASLSHPGGEGEPARSRAPAPGTAGR 211
R+S + P P + AT PR +LS P G EP APA
Sbjct: 870 PPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPA------ 923
Query: 212 GPLANQQRKWCFSEPGKLDRVGRGGGPARECLGEACSSSGLPGPEPLEF---QHPALAKF 268
GP ++ + + EPG G P+R GE GLP E Q P A
Sbjct: 924 GPASDTEEE----EPGP-----EGTPPSRGSSGE-----GLPFAEEGNLTIKQRPKPAGP 969
Query: 269 EDHEVGWLPETQPQGSMNL-DSGSLKLGDAFRPASRSRSASGEVLGSWGGSGGTIPIVQA 327
E P NL +S ++K RP R R L ++G + T A
Sbjct: 970 PPRET----PVPPGLDFNLTESDTVKR----RPKCREREPLQTALLAFGVASATPG--PA 1019
Query: 328 VPQGAETPRPLFQTKLSRFLPQKEAAVMYPAELPQS-SPADSEQRVSETCIVPAWLPSLP 386
P + TP ++ + LPQ E + + +P +P+ + Q C P S
Sbjct: 1020 APLPSPTPG---ESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLESSAA 1076
Query: 387 DEVFLE-EAPLVRMRSPPDPHASQGP-PASVHASDQPY-GTGLGQRTGQVTVPTEYPLHE 443
E E P P A P P SV + + G L R G VP P E
Sbjct: 1077 SRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAPRLGPRPVPPPRP--E 1134
Query: 444 CPGTAGADDCWQ 455
GT G Q
Sbjct: 1135 STGTVGPGQAQQ 1146
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 43.1 bits (100), Expect = 0.001
Identities = 101/417 (24%), Positives = 127/417 (30%), Gaps = 81/417 (19%)
Query: 167 LPARLRPTVPARPPATHPRSASLSHPGGEGEP-ARSRAPAPGTAG-------------RG 212
LP R P PP + PG +G P + RA PGT G RG
Sbjct: 1276 LPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRG 1335
Query: 213 PLANQQRKWCFSEPGKLDRVGRGGGPARECLGEACSSSGLPGPEPLEFQHPALAKFEDHE 272
+ + EPG +V G GP SG PGP
Sbjct: 1336 DPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPR---------------- 1379
Query: 273 VGWLPETQPQGSMNLDSGSLKLGDAFRPASRSRSASGEVLGSWGGSGGTIPIVQAVPQGA 332
G L + P+G L ++K GD R GE GG P +P
Sbjct: 1380 -GPLGDPGPRGPPGLPGTAMK-GDKGDRGERGPPGPGE--------GGIAPGEPGLPGLP 1429
Query: 333 ETPRPLFQT----KLSRFLPQKEAAVMYPAELPQSSPADSEQRVSETCIVPAWLPSLPDE 388
+P P K ++ A P + SP + R I P P
Sbjct: 1430 GSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQ--PGSPGEQGPRGPPGAIGPKGDRGFPGP 1487
Query: 389 VFLEEAPLVRMRSPPDPHASQ------GPPASVHASDQPYGTGLGQRTGQVTVPTEYPLH 442
L EA R PP P S+ G P + P TG G+ P + P
Sbjct: 1488 --LGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGD-PAV 1544
Query: 443 ECPGTAG--------------ADDCWQGVNGSVGISRPTSHTPTGTANDNIPTIDPTGLT 488
P AG QG G G+ P P G D P I TG
Sbjct: 1545 VGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGP-IGLTGRA 1603
Query: 489 TNP----PTAAESDLLKPVPADALGLSGND-------TPGPSHNTALARGTGQPGSR 534
P P + D +P P +G G D GP + L G+ G R
Sbjct: 1604 GPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLR 1660
Score = 35.4 bits (80), Expect = 0.22
Identities = 97/389 (24%), Positives = 123/389 (31%), Gaps = 68/389 (17%)
Query: 192 PGGEGEPARSRAPAPGTAGRGPLANQQRKWCFSEPGKLD------RVGRGGGPARECLGE 245
PG +G+P R PA RGP R +PG G+ G P R+ L
Sbjct: 1754 PGPQGDPG-VRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPG 1812
Query: 246 ACSSSGLPGP--------EPLEFQHPALAKFEDHEVGWLPETQPQGSMNLDSGSLKLGDA 297
GLPGP +P E P L ++ E G E +G DSG+ G
Sbjct: 1813 LRGEQGLPGPSGPPGLPGKPGEDGKPGL-NGKNGEPGDPGEDGRKGEKG-DSGA--SGRE 1868
Query: 298 FRPASRSRSASGEVLGSWGGSGGTIPI------VQAVP--QGAETPRPLFQTKLSRFLPQ 349
R + + +LG G G P+ VP G + R +K + LP
Sbjct: 1869 GRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPG 1928
Query: 350 KEAAVMYPAELPQSSPADSEQRVSETC---------IVPAWLPSLPDEVFLEEAPLVRMR 400
+ P +P + R+ ET IV W S + + E R R
Sbjct: 1929 ERGLRGEPGSVP------NVDRLLETAGIKASALREIVETWDESSGSFLPVPE----RRR 1978
Query: 401 SPPDPHASQGPPASVHASDQPYGTGL-------------GQRTGQVTVPTEYPLHECPGT 447
P QGPP P GL G G+ P L PG
Sbjct: 1979 GPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGK 2038
Query: 448 AGADDCWQGVNGSVG-ISRPTSHTPTGTAND--NIPTIDPTGLTTNPPTAAESDLLKPVP 504
G G G VG RP G + P GL P V
Sbjct: 2039 PGIPGL-PGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVD 2097
Query: 505 ADALGLSGNDTPGPSHNTALARGTGQPGS 533
GLSG P L G+PGS
Sbjct: 2098 EPGPGLSGEQGP-----PGLKGAKGEPGS 2121
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.400
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,521,401
Number of Sequences: 37866
Number of extensions: 2796326
Number of successful extensions: 17913
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 59
Number of HSP's successfully gapped in prelim test: 1001
Number of HSP's that attempted gapping in prelim test: 14030
Number of HSP's gapped (non-prelim): 4707
length of query: 847
length of database: 18,247,518
effective HSP length: 111
effective length of query: 736
effective length of database: 14,044,392
effective search space: 10336672512
effective search space used: 10336672512
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.