Guide to the Human Genome
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Name: IRS2 Sequence: fasta or formatted (1338aa) NCBI GI: 38683860
Description:

insulin receptor substrate 2

Referenced in:

Pancreas and Insulin

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            11.2        150           8
 C cysteine            1.6         21           2
 D aspartate           3.7         49           2
 E glutamate           4.2         56           3
 F phenylalanine       1.9         26           3
 G glycine            11.8        158           5
 H histidine           2.5         34           3
 I isoleucine          1.7         23           1
 K lysine              2.9         39           2
 L leucine             7.2         97           2
 M methionine          1.7         23           1
 N asparagine          2.3         31           8
 P proline            13.3        178           6
 Q glutamine           3.0         40           1
 R arginine            6.1         82           3
 S serine             13.2        177           4
 T threonine           4.0         53           3
 V valine              4.3         57           2
 W tryptophan          0.5          7           1
 Y tyrosine            2.8         37           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   insulin receptor substrate 2 
IRS1                  0.230   insulin receptor substrate 1 
IRS4                  0.100   insulin receptor substrate 4 
NACA                  0.028   nascent polypeptide-associated complex alpha subuni...
SHANK1                0.022   SH3 and multiple ankyrin repeat domains 1 
COL1A1                0.021   alpha 1 type I collagen preproprotein 
FLJ22184              0.021   PREDICTED: hypothetical protein LOC80164 
FLJ22184              0.021   PREDICTED: hypothetical protein FLJ22184 
FLJ22184              0.020   PREDICTED: hypothetical protein FLJ22184 
PRR12                 0.020   proline rich 12 
MAP1A                 0.020   microtubule-associated protein 1A 
ATN1                  0.020   atrophin-1 
ATN1                  0.020   atrophin-1 
CIC                   0.020   capicua homolog 
ARID1A                0.019   AT rich interactive domain 1A isoform a 
ARID1A                0.019   AT rich interactive domain 1A isoform b 
COL17A1               0.019   alpha 1 type XVII collagen 
TAF4                  0.018   TBP-associated factor 4 
COL3A1                0.018   collagen type III alpha 1 preproprotein 
KDM6B                 0.018   lysine (K)-specific demethylase 6B 
COL7A1                0.017   alpha 1 type VII collagen precursor 
WIPF1                 0.017   WAS/WASL interacting protein family, member 1 [Homo...
WIPF1                 0.017   WAS/WASL interacting protein family, member 1 
KIAA1522              0.017   hypothetical protein LOC57648 
COL27A1               0.017   collagen, type XXVII, alpha 1 
C6orf132              0.017   PREDICTED: chromosome 6 open reading frame 132 [Hom...
C6orf132              0.017   PREDICTED: chromosome 6 open reading frame 132 [Hom...
LOC728317             0.017   PREDICTED: hypothetical protein 
C6orf132              0.017   PREDICTED: hypothetical protein LOC647024 
COL2A1                0.016   collagen, type II, alpha 1 isoform 1 precursor [Hom...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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