Guide to the Human Genome
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Name: SHANK3 Sequence: fasta or formatted (1747aa) NCBI GI: 122937241
Description:

SH3 and multiple ankyrin repeat domains 3

Referenced in:

Ankyrin Family
Synapses
Non-Receptor Tyrosine Kinase Pathways

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            10.1        177           4
 C cysteine            0.6         11           2
 D aspartate           5.2         91           2
 E glutamate           6.2        109           3
 F phenylalanine       2.8         49           1
 G glycine             9.2        161           3
 H histidine           2.2         38           2
 I isoleucine          2.5         44           2
 K lysine              4.2         74           2
 L leucine            10.0        175           3
 M methionine          0.8         14           1
 N asparagine          1.6         28           1
 P proline            12.2        214           5
 Q glutamine           3.6         63           2
 R arginine            8.2        144           3
 S serine              9.0        157           3
 T threonine           4.2         73           2
 V valine              5.1         89           3
 W tryptophan          0.5          9           1
 Y tyrosine            1.5         27           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   SH3 and multiple ankyrin repeat domains 3 
SHANK2                0.377   SH3 and multiple ankyrin repeat domains 2 isoform 1...
SHANK1                0.253   SH3 and multiple ankyrin repeat domains 1 
LOC100133890          0.129   PREDICTED: similar to Shank2E 
SHANK2                0.067   SH3 and multiple ankyrin repeat domains 2 isoform 2 ...
NACA                  0.022   nascent polypeptide-associated complex alpha subuni...
ANKK1                 0.022   ankyrin repeat and kinase domain containing 1 
ANK1                  0.020   ankyrin 1 isoform 9 
ANK1                  0.020   ankyrin 1 isoform 1 
ANK1                  0.020   ankyrin 1 isoform 3 
ANK1                  0.020   ankyrin 1 isoform 2 
ANK1                  0.020   ankyrin 1 isoform 4 
ANK2                  0.020   ankyrin 2 isoform 3 
ANK2                  0.020   ankyrin 2 isoform 2 
ANK2                  0.020   ankyrin 2 isoform 1 
ANK3                  0.019   ankyrin 3 isoform 1 
ANKRD50               0.018   ankyrin repeat domain 50 
ANKRD28               0.018   ankyrin repeat domain 28 
LMTK3                 0.017   lemur tyrosine kinase 3 
ANKRD6                0.017   ankyrin repeat domain 6 
MIB1                  0.017   mindbomb homolog 1 
ANKRD44               0.017   ankyrin repeat domain 44 
NOTCH3                0.016   Notch homolog 3 
ANKRD52               0.016   ankyrin repeat domain 52 
ESPN                  0.016   espin 
HACE1                 0.015   HECT domain and ankyrin repeat containing, E3 ubiqu...
FLJ22184              0.015   PREDICTED: hypothetical protein LOC80164 
ANKDD1A               0.015   ankyrin repeat and death domain containing 1A 
NOTCH4                0.015   notch4 preproprotein 
EHMT1                 0.015   euchromatic histone-lysine N-methyltransferase 1 is...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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