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Search of human proteins with 28893581
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|28893581 LIM homeobox transcription factor 1, alpha isoform
a [Homo sapiens]
(382 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|28893581 LIM homeobox transcription factor 1, alpha isoform a... 785 0.0
gi|4505007 LIM homeobox transcription factor 1, beta [Homo sapiens] 504 e-143
gi|41281895 LIM homeobox transcription factor 1, alpha isoform b... 275 5e-74
gi|75677381 LIM homeobox transcription factor 1, alpha isoform c... 212 5e-55
gi|30410785 LIM homeobox protein 1 [Homo sapiens] 192 4e-49
gi|11641283 LIM homeobox protein 5 [Homo sapiens] 191 9e-49
gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens] 188 8e-48
gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens] 188 8e-48
gi|15375314 LIM homeobox protein 4 [Homo sapiens] 184 2e-46
gi|21956641 ISL LIM homeobox 2 [Homo sapiens] 175 7e-44
gi|115387114 islet-1 [Homo sapiens] 168 9e-42
gi|50083287 LIM homeobox 8 [Homo sapiens] 159 5e-39
gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens] 158 7e-39
gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens] 158 7e-39
gi|33569216 LIM homeobox 9 isoform 1 [Homo sapiens] 152 5e-37
gi|62241033 LIM homeobox 9 isoform 2 [Homo sapiens] 152 5e-37
gi|30795196 LIM homeobox protein 2 [Homo sapiens] 148 9e-36
gi|21361802 LIM domain only 3 [Homo sapiens] 108 6e-24
gi|47778935 LIM domain only 3 [Homo sapiens] 108 6e-24
gi|4505005 LIM domain only 1 [Homo sapiens] 107 2e-23
gi|5803072 LIM domain only 4 [Homo sapiens] 104 2e-22
gi|214832219 LIM domain only 2 isoform 2 [Homo sapiens] 86 4e-17
gi|214832121 LIM domain only 2 isoform 2 [Homo sapiens] 86 4e-17
gi|214832074 LIM domain only 2 isoform 1 [Homo sapiens] 86 4e-17
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens] 79 7e-15
gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens] 79 7e-15
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens] 78 2e-14
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens] 78 2e-14
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens] 74 2e-13
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 74 2e-13
>gi|28893581 LIM homeobox transcription factor 1, alpha isoform a
[Homo sapiens]
Length = 382
Score = 785 bits (2026), Expect = 0.0
Identities = 382/382 (100%), Positives = 382/382 (100%)
Query: 1 MLDGLKMEENFQSAIDTSASFSSLLGRAVSPKSVCEGCQRVILDRFLLRLNDSFWHEQCV 60
MLDGLKMEENFQSAIDTSASFSSLLGRAVSPKSVCEGCQRVILDRFLLRLNDSFWHEQCV
Sbjct: 1 MLDGLKMEENFQSAIDTSASFSSLLGRAVSPKSVCEGCQRVILDRFLLRLNDSFWHEQCV 60
Query: 61 QCASCKEPLETTCFYRDKKLYCKYDYEKLFAVKCGGCFEAIAPNEFVMRAQKSVYHLSCF 120
QCASCKEPLETTCFYRDKKLYCKYDYEKLFAVKCGGCFEAIAPNEFVMRAQKSVYHLSCF
Sbjct: 61 QCASCKEPLETTCFYRDKKLYCKYDYEKLFAVKCGGCFEAIAPNEFVMRAQKSVYHLSCF 120
Query: 121 CCCVCERQLQKGDEFVLKEGQLLCKGDYEKERELLSLVSPAASDSGKSDDEESLCKSAHG 180
CCCVCERQLQKGDEFVLKEGQLLCKGDYEKERELLSLVSPAASDSGKSDDEESLCKSAHG
Sbjct: 121 CCCVCERQLQKGDEFVLKEGQLLCKGDYEKERELLSLVSPAASDSGKSDDEESLCKSAHG 180
Query: 181 AGKGTAEEGKDHKRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQ 240
AGKGTAEEGKDHKRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQ
Sbjct: 181 AGKGTAEEGKDHKRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQ 240
Query: 241 VWFQNQRAKMKKLARRQQQQQQDQQNTQRLSSAQTNGGGSAGMEGIMNPYTALPTPQQLL 300
VWFQNQRAKMKKLARRQQQQQQDQQNTQRLSSAQTNGGGSAGMEGIMNPYTALPTPQQLL
Sbjct: 241 VWFQNQRAKMKKLARRQQQQQQDQQNTQRLSSAQTNGGGSAGMEGIMNPYTALPTPQQLL 300
Query: 301 AIEQSVYSSDPFRQGLTPPQMPGDHMHPYGAEPLFHDLDSDDTSLSNLGDCFLATSEAGP 360
AIEQSVYSSDPFRQGLTPPQMPGDHMHPYGAEPLFHDLDSDDTSLSNLGDCFLATSEAGP
Sbjct: 301 AIEQSVYSSDPFRQGLTPPQMPGDHMHPYGAEPLFHDLDSDDTSLSNLGDCFLATSEAGP 360
Query: 361 LQSRVGNPIDHLYSMQNSYFTS 382
LQSRVGNPIDHLYSMQNSYFTS
Sbjct: 361 LQSRVGNPIDHLYSMQNSYFTS 382
>gi|4505007 LIM homeobox transcription factor 1, beta [Homo sapiens]
Length = 372
Score = 504 bits (1297), Expect = e-143
Identities = 260/387 (67%), Positives = 307/387 (79%), Gaps = 20/387 (5%)
Query: 1 MLDGLKMEENFQSAIDTSASFSSLLGRAVSPKSVCEGCQRVILDRFLLRLNDSFWHEQCV 60
MLDG+KMEE+ + A+ LLG +VCEGCQR I DRFL+R+N+S WHE+C+
Sbjct: 1 MLDGIKMEEH--ALRPGPATLGVLLGSDCPHPAVCEGCQRPISDRFLMRVNESSWHEECL 58
Query: 61 QCASCKEPLETTCFYRDKKLYCKYDYEKLFAVKCGGCFEAIAPNEFVMRAQKSVYHLSCF 120
QCA+C++ L T+C++RD+KLYCK DY++LFA KC GC E IAP EFVMRA + VYHL CF
Sbjct: 59 QCAACQQALTTSCYFRDRKLYCKQDYQQLFAAKCSGCMEKIAPTEFVMRALECVYHLGCF 118
Query: 121 CCCVCERQLQKGDEFVLKEGQLLCKGDYEKERELLSLVSPAASDSGKSDDEESLCKSAHG 180
CCCVCERQL+KGDEFVLKEGQLLCKGDYEKE++LLS VSP SDS KS+DE+ K A G
Sbjct: 119 CCCVCERQLRKGDEFVLKEGQLLCKGDYEKEKDLLSSVSPDESDSVKSEDEDGDMKPAKG 178
Query: 181 AG---KGTAEEGKDHKRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVR 237
G KG+ ++GKD +RPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVR
Sbjct: 179 QGSQSKGSGDDGKDPRRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVR 238
Query: 238 VVQVWFQNQRAKMKKLARRQQQQQQDQQNTQRLSSAQTNGGGSAGMEGIMNPYTAL-PTP 296
VVQVWFQNQRAKMKKLARR QQQQ+QQN+QRL S+ MEG+M YT L P
Sbjct: 239 VVQVWFQNQRAKMKKLARR-HQQQQEQQNSQRLGQEVL----SSRMEGMMASYTPLAPPQ 293
Query: 297 QQLLAIEQSVY-SSDPFRQGLTPPQMPGDHMHPYGAEPLFHDLDSDDTSLSNLGDCFLAT 355
QQ++A+EQS Y SSDPF+QGLTPPQMPG+ + +FHD+DS DTSL++L DCFL +
Sbjct: 294 QQIVAMEQSPYGSSDPFQQGLTPPQMPGN-------DSIFHDIDS-DTSLTSLSDCFLGS 345
Query: 356 SEAGPLQSRVGNPIDHLYSMQNSYFTS 382
S+ G LQ+RVGNPID LYSMQ+SYF S
Sbjct: 346 SDVGSLQARVGNPIDRLYSMQSSYFAS 372
>gi|41281895 LIM homeobox transcription factor 1, alpha isoform b
[Homo sapiens]
Length = 133
Score = 275 bits (703), Expect = 5e-74
Identities = 133/133 (100%), Positives = 133/133 (100%)
Query: 250 MKKLARRQQQQQQDQQNTQRLSSAQTNGGGSAGMEGIMNPYTALPTPQQLLAIEQSVYSS 309
MKKLARRQQQQQQDQQNTQRLSSAQTNGGGSAGMEGIMNPYTALPTPQQLLAIEQSVYSS
Sbjct: 1 MKKLARRQQQQQQDQQNTQRLSSAQTNGGGSAGMEGIMNPYTALPTPQQLLAIEQSVYSS 60
Query: 310 DPFRQGLTPPQMPGDHMHPYGAEPLFHDLDSDDTSLSNLGDCFLATSEAGPLQSRVGNPI 369
DPFRQGLTPPQMPGDHMHPYGAEPLFHDLDSDDTSLSNLGDCFLATSEAGPLQSRVGNPI
Sbjct: 61 DPFRQGLTPPQMPGDHMHPYGAEPLFHDLDSDDTSLSNLGDCFLATSEAGPLQSRVGNPI 120
Query: 370 DHLYSMQNSYFTS 382
DHLYSMQNSYFTS
Sbjct: 121 DHLYSMQNSYFTS 133
>gi|75677381 LIM homeobox transcription factor 1, alpha isoform c
[Homo sapiens]
Length = 100
Score = 212 bits (539), Expect = 5e-55
Identities = 100/100 (100%), Positives = 100/100 (100%)
Query: 283 MEGIMNPYTALPTPQQLLAIEQSVYSSDPFRQGLTPPQMPGDHMHPYGAEPLFHDLDSDD 342
MEGIMNPYTALPTPQQLLAIEQSVYSSDPFRQGLTPPQMPGDHMHPYGAEPLFHDLDSDD
Sbjct: 1 MEGIMNPYTALPTPQQLLAIEQSVYSSDPFRQGLTPPQMPGDHMHPYGAEPLFHDLDSDD 60
Query: 343 TSLSNLGDCFLATSEAGPLQSRVGNPIDHLYSMQNSYFTS 382
TSLSNLGDCFLATSEAGPLQSRVGNPIDHLYSMQNSYFTS
Sbjct: 61 TSLSNLGDCFLATSEAGPLQSRVGNPIDHLYSMQNSYFTS 100
>gi|30410785 LIM homeobox protein 1 [Homo sapiens]
Length = 406
Score = 192 bits (488), Expect = 4e-49
Identities = 98/235 (41%), Positives = 139/235 (59%), Gaps = 16/235 (6%)
Query: 35 CEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLETTCFYRDKKLYCKYDYEKLFAVKC 94
C GC+R ILDRFLL + D WH +CVQC CK L CF R+ KLYCK D+ + F KC
Sbjct: 4 CAGCKRPILDRFLLNVLDRAWHVKCVQCCECKCNLTEKCFSREGKLYCKNDFFRCFGTKC 63
Query: 95 GGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDE-FVLKEGQLLCKGDY----- 148
GC + I+P++ V RA+ V+HL+CF C +C +QL G+E +++ E + +CK DY
Sbjct: 64 AGCAQGISPSDLVRRARSKVFHLNCFTCMMCNKQLSTGEELYIIDENKFVCKEDYLSNSS 123
Query: 149 -EKERELLSL-------VSPAASDSGKSD--DEESLCKSAHGAGKGTAEEGKDHKRPKRP 198
KE L S +SP + D + D D ES S AG ++ + + P
Sbjct: 124 VAKENSLHSATTGSDPSLSPDSQDPSQDDAKDSESANVSDKEAGSNENDDQNLGAKRRGP 183
Query: 199 RTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKL 253
RT + +Q KA+F + KP R +RE LA ETGL++RV+QVWFQN+R+K +++
Sbjct: 184 RTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRM 238
>gi|11641283 LIM homeobox protein 5 [Homo sapiens]
Length = 402
Score = 191 bits (485), Expect = 9e-49
Identities = 99/236 (41%), Positives = 143/236 (60%), Gaps = 19/236 (8%)
Query: 35 CEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLETTCFYRDKKLYCKYDYEKLFAVKC 94
C GC+R ILDRFLL + D WH +CVQC CK L CF R+ KLYCK D+ + F KC
Sbjct: 5 CAGCERPILDRFLLNVLDRAWHIKCVQCCECKTNLSEKCFSREGKLYCKNDFFRRFGTKC 64
Query: 95 GGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDE-FVLKEGQLLCKGDY----- 148
GC + I+P++ V +A+ V+HL+CF C VC +QL G+E +V+ E + +CK DY
Sbjct: 65 AGCAQGISPSDLVRKARSKVFHLNCFTCMVCNKQLSTGEELYVIDENKFVCKDDYLSSSS 124
Query: 149 EKERELLSL-------VSPAASDSGKSDDEESLCKSAHGAGKGTA----EEGKDHKRPKR 197
KE L S+ +SP D+ + D +E+ ++ + K TA EE + +
Sbjct: 125 LKEGSLNSVSSCTDRSLSPDLQDALQDDPKET--DNSTSSDKETANNENEEQNSGTKRRG 182
Query: 198 PRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKL 253
PRT + +Q KA+F + KP R +RE LA ETGL++RV+QVWFQN+R+K +++
Sbjct: 183 PRTTIKAKQLETLKAAFAATPKPTRHIREQLAQETGLNMRVIQVWFQNRRSKERRM 238
>gi|30023847 LIM homeobox protein 3 isoform a [Homo sapiens]
Length = 397
Score = 188 bits (477), Expect = 8e-48
Identities = 97/232 (41%), Positives = 128/232 (55%), Gaps = 36/232 (15%)
Query: 34 VCEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLETTCFYRDKKLYCKYDYEKLFAVK 93
+C GC + ILDRF+L+ D WH +C++C+ C PL CF R + +YCK D+ K F K
Sbjct: 30 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTK 89
Query: 94 CGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKE-GQLLCKGDYEKER 152
C C I P + V RAQ VYHL CF C VC+RQL GDEF L E +L+CK DYE
Sbjct: 90 CAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE--- 146
Query: 153 ELLSLVSPAASDSGKSDDEESLCKSAHGAGKGTAEEGKDHKRPKRPRTILTTQQRRAFKA 212
TA++ + KRPRT +T +Q K+
Sbjct: 147 --------------------------------TAKQREAEATAKRPRTTITAKQLETLKS 174
Query: 213 SFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRQQQQQQDQ 264
++ S KP R VRE L++ETGL +RVVQVWFQN+RAK K+L + +Q+ Q
Sbjct: 175 AYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRQRWGQ 226
>gi|7657303 LIM homeobox protein 3 isoform b [Homo sapiens]
Length = 402
Score = 188 bits (477), Expect = 8e-48
Identities = 97/232 (41%), Positives = 128/232 (55%), Gaps = 36/232 (15%)
Query: 34 VCEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLETTCFYRDKKLYCKYDYEKLFAVK 93
+C GC + ILDRF+L+ D WH +C++C+ C PL CF R + +YCK D+ K F K
Sbjct: 35 LCAGCDQHILDRFILKALDRHWHSKCLKCSDCHTPLAERCFSRGESVYCKDDFFKRFGTK 94
Query: 94 CGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKE-GQLLCKGDYEKER 152
C C I P + V RAQ VYHL CF C VC+RQL GDEF L E +L+CK DYE
Sbjct: 95 CAACQLGIPPTQVVRRAQDFVYHLHCFACVVCKRQLATGDEFYLMEDSRLVCKADYE--- 151
Query: 153 ELLSLVSPAASDSGKSDDEESLCKSAHGAGKGTAEEGKDHKRPKRPRTILTTQQRRAFKA 212
TA++ + KRPRT +T +Q K+
Sbjct: 152 --------------------------------TAKQREAEATAKRPRTTITAKQLETLKS 179
Query: 213 SFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRQQQQQQDQ 264
++ S KP R VRE L++ETGL +RVVQVWFQN+RAK K+L + +Q+ Q
Sbjct: 180 AYNTSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKKDAGRQRWGQ 231
>gi|15375314 LIM homeobox protein 4 [Homo sapiens]
Length = 390
Score = 184 bits (466), Expect = 2e-46
Identities = 98/233 (42%), Positives = 131/233 (56%), Gaps = 35/233 (15%)
Query: 24 LLGRAVSPKSVCEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLETTCFYRDKKLYCK 83
+LG + C GC + ILD+F+L++ D WH C++CA C+ L CF R +YCK
Sbjct: 19 MLGVPMQQIPQCAGCNQHILDKFILKVLDRHWHSSCLKCADCQMQLADRCFSRAGSVYCK 78
Query: 84 YDYEKLFAVKCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKE-GQL 142
D+ K F KC C + I P + V +AQ VYHL CF C +C RQL GDEF L E G+L
Sbjct: 79 EDFFKRFGTKCTACQQGIPPTQVVRKAQDFVYHLHCFACIICNRQLATGDEFYLMEDGRL 138
Query: 143 LCKGDYEKERELLSLVSPAASDSGKSDDEESLCKSAHGAGKGTAEEGKDHKRPKRPRTIL 202
+CK DYE ++ +DD E+ GA KRPRT +
Sbjct: 139 VCKEDYETAKQ--------------NDDSEA------GA--------------KRPRTTI 164
Query: 203 TTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLAR 255
T +Q K +++ S KP R VRE L++ETGL +RVVQVWFQN+RAK K+L +
Sbjct: 165 TAKQLETLKNAYKNSPKPARHVREQLSSETGLDMRVVQVWFQNRRAKEKRLKK 217
>gi|21956641 ISL LIM homeobox 2 [Homo sapiens]
Length = 359
Score = 175 bits (443), Expect = 7e-44
Identities = 99/256 (38%), Positives = 142/256 (55%), Gaps = 12/256 (4%)
Query: 33 SVCEGCQRVILDRFLLRLN-DSFWHEQCVQCASCKEPLETTC--FYRDKKLYCKYDYEKL 89
++C GC I D+F+LR++ D WH C++CA C + L+ TC F RD K YCK DY +L
Sbjct: 25 AMCVGCGSQIHDQFILRVSPDLEWHAACLKCAECSQYLDETCTCFVRDGKTYCKRDYVRL 84
Query: 90 FAVKCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDYE 149
F +KC C + ++ VMRA+ SVYH+ CF C VC RQL GDEF L+E +LLC+ D+
Sbjct: 85 FGIKCAKCQVGFSSSDLVMRARDSVYHIECFRCSVCSRQLLPGDEFSLREHELLCRADHG 144
Query: 150 KERELLSLVSPAASDSGKSDDEESLCKSAHGAGKGTAEEGKDHKRPK---RPRTILTTQQ 206
E + SP + G L G+G+ A HK+ + R RT+L +Q
Sbjct: 145 LLLERAAAGSPRS--PGPLPGARGLHLPDAGSGRQPALRPHVHKQTEKTTRVRTVLNEKQ 202
Query: 207 RRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKK----LARRQQQQQQ 262
+ + + +P ++E L TGLS RV++VWFQN+R K KK + + QQQQ
Sbjct: 203 LHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKKSILMKQLQQQQHS 262
Query: 263 DQQNTQRLSSAQTNGG 278
D+ + Q L+ G
Sbjct: 263 DKTSLQGLTGTPLVAG 278
>gi|115387114 islet-1 [Homo sapiens]
Length = 349
Score = 168 bits (425), Expect = 9e-42
Identities = 96/251 (38%), Positives = 139/251 (55%), Gaps = 16/251 (6%)
Query: 33 SVCEGCQRVILDRFLLRLN-DSFWHEQCVQCASCKEPLET--TCFYRDKKLYCKYDYEKL 89
S+C GC I D+++LR++ D WH C++CA C + L+ TCF RD K YCK DY +L
Sbjct: 15 SLCVGCGNQIHDQYILRVSPDLEWHAACLKCAECNQYLDESCTCFVRDGKTYCKRDYIRL 74
Query: 90 FAVKCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDYE 149
+ +KC C + N+FVMRA+ VYH+ CF C C RQL GDEF L+E L C+ D++
Sbjct: 75 YGIKCAKCSIGFSKNDFVMRARSKVYHIECFRCVACSRQLIPGDEFALREDGLFCRADHD 134
Query: 150 -KERELLSLVSPAASDSGKSDDEESLCKSAHG-AGKGTAEEGKDHKRPK---RPRTILTT 204
ER L P + L +A + + A HK+P+ R RT+L
Sbjct: 135 VVERASLGAGDPLS----PLHPARPLQMAAEPISARQPALRPHVHKQPEKTTRVRTVLNE 190
Query: 205 QQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKK----LARRQQQQ 260
+Q + + + +P ++E L TGLS RV++VWFQN+R K KK + + QQQQ
Sbjct: 191 KQLHTLRTCYAANPRPDALMKEQLVEMTGLSPRVIRVWFQNKRCKDKKRSIMMKQLQQQQ 250
Query: 261 QQDQQNTQRLS 271
D+ N Q ++
Sbjct: 251 PNDKTNIQGMT 261
>gi|50083287 LIM homeobox 8 [Homo sapiens]
Length = 356
Score = 159 bits (401), Expect = 5e-39
Identities = 85/224 (37%), Positives = 125/224 (55%), Gaps = 16/224 (7%)
Query: 32 KSVCEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPL--ETTCFYRDKKLYCKYDYEKL 89
K VC C I+D++LL++ND WH +C+ C+ C+ L T+C+ +DK ++CK DY +
Sbjct: 72 KCVCNSCGLEIVDKYLLKVNDLCWHVRCLSCSVCRTSLGRHTSCYIKDKDIFCKLDYFRR 131
Query: 90 FAVKCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDYE 149
+ +C C I ++V RA+ +VYHL+CF C C+RQL G+EF L E ++LC+ Y+
Sbjct: 132 YGTRCSRCGRHIHSTDWVRRAKGNVYHLACFACFSCKRQLSTGEEFALVEEKVLCRVHYD 191
Query: 150 KERELLSLVSPAASDSGKSDDEESLCKSAHGAGKGTAEEGKDHKRP-KRPRTILTTQQRR 208
D+ K + E S GA E+ +H +P KR RT T Q +
Sbjct: 192 -----------CMLDNLKREVENGNGISVEGA--LLTEQDVNHPKPAKRARTSFTADQLQ 238
Query: 209 AFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKK 252
+A F + P + + LA TGLS RV+QVWFQN RA+ KK
Sbjct: 239 VMQAQFAQDNNPDAQTLQKLAERTGLSRRVIQVWFQNCRARHKK 282
>gi|134284361 LIM homeobox protein 6 isoform 2 [Homo sapiens]
Length = 377
Score = 158 bits (400), Expect = 7e-39
Identities = 105/306 (34%), Positives = 158/306 (51%), Gaps = 31/306 (10%)
Query: 32 KSVCEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPL--ETTCFYRDKKLYCKYDYEKL 89
K++C C ILDR+LL++N+ WH +C++C+ C+ L + +C+ ++K+++CK DY
Sbjct: 96 KNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSR 155
Query: 90 FAVKCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDYE 149
F KC C I +++V RA+ + YHL+CF C C+RQL G+EF L E ++LC+ Y+
Sbjct: 156 FGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYD 215
Query: 150 KERELLSLVSPAASDSGKSDDEESLCKSAHGAGKGTAEEGKDHKRPKRPRTILTTQQRRA 209
E L A+++G E G +E+ K KR RT T +Q +
Sbjct: 216 TMIENLK----RAAENGNGLTLE---------GAVPSEQDSQPKPAKRARTSFTAEQLQV 262
Query: 210 FKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRQQQQQQDQQNTQR 269
+A F + P + + LA TGLS RV+QVWFQN RA+ KK Q+
Sbjct: 263 MQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKK---------HTPQHPVP 313
Query: 270 LSSAQTNGGGSAGMEGIMNPYTALPTPQQLLAIEQSVY-SSDPFRQGLTPPQMPGDHMHP 328
S A + SA + I YT +P++ + Y S PF LT P +P H+ P
Sbjct: 314 PSGAPPSRLPSALSDDI--HYTPFSSPERARMVTLHGYIESHPF-SVLTLPALP--HL-P 367
Query: 329 YGAEPL 334
GA L
Sbjct: 368 VGAPQL 373
>gi|134284359 LIM homeobox protein 6 isoform 1 [Homo sapiens]
Length = 392
Score = 158 bits (400), Expect = 7e-39
Identities = 104/321 (32%), Positives = 160/321 (49%), Gaps = 33/321 (10%)
Query: 32 KSVCEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPL--ETTCFYRDKKLYCKYDYEKL 89
K++C C ILDR+LL++N+ WH +C++C+ C+ L + +C+ ++K+++CK DY
Sbjct: 96 KNICSSCGLEILDRYLLKVNNLIWHVRCLECSVCRTSLRQQNSCYIKNKEIFCKMDYFSR 155
Query: 90 FAVKCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDYE 149
F KC C I +++V RA+ + YHL+CF C C+RQL G+EF L E ++LC+ Y+
Sbjct: 156 FGTKCARCGRQIYASDWVRRARGNAYHLACFACFSCKRQLSTGEEFGLVEEKVLCRIHYD 215
Query: 150 KERELLSLVSPAASDSGKSDDEESLCKSAHGAGKGTAEEGKDHKRPKRPRTILTTQQRRA 209
E L A+++G E G +E+ K KR RT T +Q +
Sbjct: 216 TMIENLK----RAAENGNGLTLE---------GAVPSEQDSQPKPAKRARTSFTAEQLQV 262
Query: 210 FKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRQQQQQQDQQNTQR 269
+A F + P + + LA TGLS RV+QVWFQN RA+ KK Q+
Sbjct: 263 MQAQFAQDNNPDAQTLQKLADMTGLSRRVIQVWFQNCRARHKK---------HTPQHPVP 313
Query: 270 LSSAQTNGGGSAGMEGIMNPYTALPTPQQLLAIEQSVYSSDPFRQGLTPPQMPGDHMHPY 329
S A + SA + I YT +P++ + Y + G ++ PY
Sbjct: 314 PSGAPPSRLPSALSDDI--HYTPFSSPERARMVTLHGYIESQVQCGQVHCRL------PY 365
Query: 330 GAEPLFHDLDSDDTSLSNLGD 350
A P+ D D LSN G+
Sbjct: 366 TAPPVHLKADMDG-PLSNRGE 385
>gi|33569216 LIM homeobox 9 isoform 1 [Homo sapiens]
Length = 397
Score = 152 bits (384), Expect = 5e-37
Identities = 102/324 (31%), Positives = 148/324 (45%), Gaps = 38/324 (11%)
Query: 33 SVCEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLET--TCFYRDKKLYCKYDYEKLF 90
++C GC I DR+ L D WH +C++C CK LE+ TCF +D +YCK DY + F
Sbjct: 69 ALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRF 128
Query: 91 AV-KCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDYE 149
+V +C C I+ +E VMRA+ SVYHLSCF C C + L GD F +K+ + C+ +E
Sbjct: 129 SVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFE 188
Query: 150 KERE-----LLSLVSPAASDSG-----------------KSDDEESLCKSAHGAGKGTAE 187
+ LS AA G + +L G E
Sbjct: 189 TLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNE 248
Query: 188 EGKDH-----------KRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSV 236
DH ++ KR RT Q R K+ F ++ P K + LA +TGL+
Sbjct: 249 NEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTK 308
Query: 237 RVVQVWFQNQRAKMKKLARRQQQQQQDQQNTQRLSSAQTNGGGSAGMEGIMNPYTALPTP 296
RV+QVWFQN RAK ++ RQ+ D+ + L + + G+ G T L P
Sbjct: 309 RVLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALTPPGTATTLTDLTNP 368
Query: 297 QQLLAIEQSVYSSDPFRQGLTPPQ 320
+ + SV S+ + +P Q
Sbjct: 369 --TITVVTSVTSNMDSHESGSPSQ 390
>gi|62241033 LIM homeobox 9 isoform 2 [Homo sapiens]
Length = 388
Score = 152 bits (384), Expect = 5e-37
Identities = 102/324 (31%), Positives = 148/324 (45%), Gaps = 38/324 (11%)
Query: 33 SVCEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLET--TCFYRDKKLYCKYDYEKLF 90
++C GC I DR+ L D WH +C++C CK LE+ TCF +D +YCK DY + F
Sbjct: 60 ALCAGCGGKISDRYYLLAVDKQWHLRCLKCCECKLALESELTCFAKDGSIYCKEDYYRRF 119
Query: 91 AV-KCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDYE 149
+V +C C I+ +E VMRA+ SVYHLSCF C C + L GD F +K+ + C+ +E
Sbjct: 120 SVQRCARCHLGISASEMVMRARDSVYHLSCFTCSTCNKTLTTGDHFGMKDSLVYCRAHFE 179
Query: 150 KERE-----LLSLVSPAASDSG-----------------KSDDEESLCKSAHGAGKGTAE 187
+ LS AA G + +L G E
Sbjct: 180 TLLQGEYPPQLSYTELAAKSGGLALPYFNGTGTVQKGRPRKRKSPALGVDIVNYNSGCNE 239
Query: 188 EGKDH-----------KRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSV 236
DH ++ KR RT Q R K+ F ++ P K + LA +TGL+
Sbjct: 240 NEADHLDRDQQPYPPSQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTK 299
Query: 237 RVVQVWFQNQRAKMKKLARRQQQQQQDQQNTQRLSSAQTNGGGSAGMEGIMNPYTALPTP 296
RV+QVWFQN RAK ++ RQ+ D+ + L + + G+ G T L P
Sbjct: 300 RVLQVWFQNARAKFRRNLLRQENGGVDKADGTSLPAPPSADSGALTPPGTATTLTDLTNP 359
Query: 297 QQLLAIEQSVYSSDPFRQGLTPPQ 320
+ + SV S+ + +P Q
Sbjct: 360 --TITVVTSVTSNMDSHESGSPSQ 381
>gi|30795196 LIM homeobox protein 2 [Homo sapiens]
Length = 406
Score = 148 bits (373), Expect = 9e-36
Identities = 109/359 (30%), Positives = 158/359 (44%), Gaps = 63/359 (17%)
Query: 13 SAIDTSASFSSLLGRAVSPKSVCEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLET- 71
SAID + +++ + ++C GC I DR+ L D WH +C++C CK LE+
Sbjct: 31 SAIDRGDTETTMPSISSDRAALCAGCGGKISDRYYLLAVDKQWHMRCLKCCECKLNLESE 90
Query: 72 -TCFYRDKKLYCKYDYEKLFAV-KCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQL 129
TCF +D +YCK DY + F+V +C C I+ +E VMRA+ VYHL+CF C C + L
Sbjct: 91 LTCFSKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDLVYHLNCFTCTTCNKML 150
Query: 130 QKGDEFVLKEGQLLCKGDYEKERELLSLVSPA-------ASDSGKSDDEESLCKSAHGA- 181
GD F +K+ + C+ +E LL PA A+ + + +S A GA
Sbjct: 151 TTGDHFGMKDSLVYCRLHFE---ALLQGEYPAHFNHADVAAAAAAAAAAKSAGLGAAGAN 207
Query: 182 --------GKGTAEEGKDHKR-------------------------------------PK 196
G GT ++G+ KR K
Sbjct: 208 PLGLPYYNGVGTVQKGRPRKRKSPGPGADLAAYNAALSCNENDAEHLDRDQPYPSSQKTK 267
Query: 197 RPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARR 256
R RT Q R K+ F ++ P K + LA +TGL+ RV+QVWFQN RAK ++ R
Sbjct: 268 RMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLR 327
Query: 257 QQQQQQDQQNTQRLSSAQTNGGGS----AGMEGIMNPYTALPTPQQLLAIEQSVYSSDP 311
Q+ D+ L + +G S A + P T L SV +S P
Sbjct: 328 QENTGVDKSTDAALQTGTPSGPASELSNASLSPSSTPTTLTDLTSPTLPTVTSVLTSVP 386
>gi|21361802 LIM domain only 3 [Homo sapiens]
Length = 145
Score = 108 bits (271), Expect = 6e-24
Identities = 51/121 (42%), Positives = 72/121 (59%), Gaps = 5/121 (4%)
Query: 35 CEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLE---TTCFYRDKKLYCKYDYEKLFA 91
C GC R I DR+LL+ D +WHE C++CA C L +T + + + C+ DY +LF
Sbjct: 13 CAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFG 72
Query: 92 V--KCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDYE 149
V C C + I E VMRA+ +VYHL CF C +C ++ GD+F LK +LC+ DYE
Sbjct: 73 VTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQTDYE 132
Query: 150 K 150
+
Sbjct: 133 E 133
>gi|47778935 LIM domain only 3 [Homo sapiens]
Length = 145
Score = 108 bits (271), Expect = 6e-24
Identities = 51/121 (42%), Positives = 72/121 (59%), Gaps = 5/121 (4%)
Query: 35 CEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLE---TTCFYRDKKLYCKYDYEKLFA 91
C GC R I DR+LL+ D +WHE C++CA C L +T + + + C+ DY +LF
Sbjct: 13 CAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFG 72
Query: 92 V--KCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDYE 149
V C C + I E VMRA+ +VYHL CF C +C ++ GD+F LK +LC+ DYE
Sbjct: 73 VTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQRFCVGDKFFLKNNMILCQTDYE 132
Query: 150 K 150
+
Sbjct: 133 E 133
>gi|4505005 LIM domain only 1 [Homo sapiens]
Length = 156
Score = 107 bits (267), Expect = 2e-23
Identities = 53/131 (40%), Positives = 75/131 (57%), Gaps = 8/131 (6%)
Query: 28 AVSPKSV---CEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLE---TTCFYRDKKLY 81
+V PK C GC R I DR+LL+ D +WHE C++CA C L +T + + +
Sbjct: 14 SVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLIL 73
Query: 82 CKYDYEKLFAV--KCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKE 139
C+ DY +LF C C + I E VMRA+ +VYHL CF C +C ++ GD+F LK
Sbjct: 74 CRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRFCVGDKFFLKN 133
Query: 140 GQLLCKGDYEK 150
+LC+ DYE+
Sbjct: 134 NMILCQMDYEE 144
>gi|5803072 LIM domain only 4 [Homo sapiens]
Length = 165
Score = 104 bits (259), Expect = 2e-22
Identities = 49/118 (41%), Positives = 67/118 (56%), Gaps = 5/118 (4%)
Query: 35 CEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLE---TTCFYRDKKLYCKYDYEKLFA 91
C GC I DRFLL DS+WH +C++C+ C+ L T+C+ + + C+ DY +LF
Sbjct: 23 CAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDIGTSCYTKSGMILCRNDYIRLFG 82
Query: 92 VK--CGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGD 147
C C ++I +E VMRAQ +VYHL CF C C +L GD F G L C+ D
Sbjct: 83 NSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRNRLVPGDRFHYINGSLFCEHD 140
Score = 42.7 bits (99), Expect = 5e-04
Identities = 30/89 (33%), Positives = 40/89 (44%), Gaps = 6/89 (6%)
Query: 93 KCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQK-GDEFVLKEGQLLCKGDYEKE 151
+C GC IA + F++ A S +H C C C+ QL G K G +LC+ DY +
Sbjct: 22 RCAGCGGKIA-DRFLLYAMDSYWHSRCLKCSCCQAQLGDIGTSCYTKSGMILCRNDYIR- 79
Query: 152 RELLSLVSPAASDSGKSDDEESLCKSAHG 180
L S A S G+S L A G
Sbjct: 80 ---LFGNSGACSACGQSIPASELVMRAQG 105
>gi|214832219 LIM domain only 2 isoform 2 [Homo sapiens]
Length = 158
Score = 86.3 bits (212), Expect = 4e-17
Identities = 41/118 (34%), Positives = 60/118 (50%), Gaps = 5/118 (4%)
Query: 35 CEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLETT---CFYRDKKLYCKYDYEKLFA 91
C GCQ+ I DR+ L+ D +WHE C+ C C L +Y+ + C+ DY +LF
Sbjct: 30 CGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLFG 89
Query: 92 VK--CGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGD 147
C C + I E MR + VYHL CF C C++ GD ++L ++C+ D
Sbjct: 90 QDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIVCEQD 147
>gi|214832121 LIM domain only 2 isoform 2 [Homo sapiens]
Length = 158
Score = 86.3 bits (212), Expect = 4e-17
Identities = 41/118 (34%), Positives = 60/118 (50%), Gaps = 5/118 (4%)
Query: 35 CEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLETT---CFYRDKKLYCKYDYEKLFA 91
C GCQ+ I DR+ L+ D +WHE C+ C C L +Y+ + C+ DY +LF
Sbjct: 30 CGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLFG 89
Query: 92 VK--CGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGD 147
C C + I E MR + VYHL CF C C++ GD ++L ++C+ D
Sbjct: 90 QDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIVCEQD 147
>gi|214832074 LIM domain only 2 isoform 1 [Homo sapiens]
Length = 227
Score = 86.3 bits (212), Expect = 4e-17
Identities = 41/118 (34%), Positives = 60/118 (50%), Gaps = 5/118 (4%)
Query: 35 CEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLETT---CFYRDKKLYCKYDYEKLFA 91
C GCQ+ I DR+ L+ D +WHE C+ C C L +Y+ + C+ DY +LF
Sbjct: 99 CGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLFG 158
Query: 92 VK--CGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGD 147
C C + I E MR + VYHL CF C C++ GD ++L ++C+ D
Sbjct: 159 QDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIVCEQD 216
>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
Length = 423
Score = 79.0 bits (193), Expect = 7e-15
Identities = 39/112 (34%), Positives = 59/112 (52%), Gaps = 3/112 (2%)
Query: 35 CEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLETTCFYRDKKL-YCKYDYEKLFAVK 93
C C++ I + L + WH C CA+CK P+ FY ++ + YC+ DYEK+F K
Sbjct: 307 CAKCKKKITGEIMHALKMT-WHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTK 365
Query: 94 CGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCK 145
C GC I + + A +H +CF C +C+ L+ G F K+ + LCK
Sbjct: 366 CHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLE-GKTFYSKKDRPLCK 416
Score = 69.3 bits (168), Expect = 5e-12
Identities = 38/118 (32%), Positives = 62/118 (52%), Gaps = 5/118 (4%)
Query: 34 VCEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLETTCFYRDK-KLYCKYDYEKLFAV 92
VC C +VI R+L+ L ++ E+ V C+ C + LE F+ +K ++C Y+ +A
Sbjct: 247 VCHQCHKVIRGRYLVALGHAYHPEEFV-CSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 305
Query: 93 KCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDYEK 150
C C + I +M A K +H+ CF C C+ + + F ++EG C+ DYEK
Sbjct: 306 SCAKCKKKITGE--IMHALKMTWHVHCFTCAACKTPI-RNRAFYMEEGVPYCERDYEK 360
>gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
Length = 457
Score = 79.0 bits (193), Expect = 7e-15
Identities = 39/112 (34%), Positives = 59/112 (52%), Gaps = 3/112 (2%)
Query: 35 CEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLETTCFYRDKKL-YCKYDYEKLFAVK 93
C C++ I + L + WH C CA+CK P+ FY ++ + YC+ DYEK+F K
Sbjct: 341 CAKCKKKITGEIMHALKMT-WHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTK 399
Query: 94 CGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCK 145
C GC I + + A +H +CF C +C+ L+ G F K+ + LCK
Sbjct: 400 CHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLE-GKTFYSKKDRPLCK 450
Score = 69.3 bits (168), Expect = 5e-12
Identities = 38/118 (32%), Positives = 62/118 (52%), Gaps = 5/118 (4%)
Query: 34 VCEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLETTCFYRDK-KLYCKYDYEKLFAV 92
VC C +VI R+L+ L ++ E+ V C+ C + LE F+ +K ++C Y+ +A
Sbjct: 281 VCHQCHKVIRGRYLVALGHAYHPEEFV-CSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAP 339
Query: 93 KCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDYEK 150
C C + I +M A K +H+ CF C C+ + + F ++EG C+ DYEK
Sbjct: 340 SCAKCKKKITGE--IMHALKMTWHVHCFTCAACKTPI-RNRAFYMEEGVPYCERDYEK 394
>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
Length = 487
Score = 77.8 bits (190), Expect = 2e-14
Identities = 43/116 (37%), Positives = 62/116 (53%), Gaps = 5/116 (4%)
Query: 34 VCEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLETTCFYRDK-KLYCKYDYEKLFAV 92
+C C +VI FL+ L S WH + CA CK + F +K LYC+ YEK FA
Sbjct: 310 MCAHCNQVIRGPFLVALGKS-WHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 368
Query: 93 KCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDY 148
+CG C I V+ A K +H+SCF C C + + + + F L++G+ C+ DY
Sbjct: 369 ECGRCQRKILGE--VISALKQTWHVSCFVCVACGKPI-RNNVFHLEDGEPYCETDY 421
Score = 73.2 bits (178), Expect = 4e-13
Identities = 39/112 (34%), Positives = 54/112 (48%), Gaps = 3/112 (2%)
Query: 35 CEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLETTCFY-RDKKLYCKYDYEKLFAVK 93
C CQR IL + L + WH C C +C +P+ F+ D + YC+ DY LF
Sbjct: 370 CGRCQRKILGEVISALKQT-WHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTI 428
Query: 94 CGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCK 145
C GC I + + A +H +CF C VC L+ G F K+ + LCK
Sbjct: 429 CHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLE-GQTFFSKKDKPLCK 479
>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
Length = 596
Score = 77.8 bits (190), Expect = 2e-14
Identities = 43/116 (37%), Positives = 62/116 (53%), Gaps = 5/116 (4%)
Query: 34 VCEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLETTCFYRDK-KLYCKYDYEKLFAV 92
+C C +VI FL+ L S WH + CA CK + F +K LYC+ YEK FA
Sbjct: 419 MCAHCNQVIRGPFLVALGKS-WHPEEFNCAHCKNTMAYIGFVEEKGALYCELCYEKFFAP 477
Query: 93 KCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDY 148
+CG C I V+ A K +H+SCF C C + + + + F L++G+ C+ DY
Sbjct: 478 ECGRCQRKILGE--VISALKQTWHVSCFVCVACGKPI-RNNVFHLEDGEPYCETDY 530
Score = 73.2 bits (178), Expect = 4e-13
Identities = 39/112 (34%), Positives = 54/112 (48%), Gaps = 3/112 (2%)
Query: 35 CEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLETTCFY-RDKKLYCKYDYEKLFAVK 93
C CQR IL + L + WH C C +C +P+ F+ D + YC+ DY LF
Sbjct: 479 CGRCQRKILGEVISALKQT-WHVSCFVCVACGKPIRNNVFHLEDGEPYCETDYYALFGTI 537
Query: 94 CGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCK 145
C GC I + + A +H +CF C VC L+ G F K+ + LCK
Sbjct: 538 CHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLE-GQTFFSKKDKPLCK 588
>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
Length = 617
Score = 74.3 bits (181), Expect = 2e-13
Identities = 38/113 (33%), Positives = 57/113 (50%), Gaps = 3/113 (2%)
Query: 34 VCEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLETTCFY-RDKKLYCKYDYEKLFAV 92
+C C I+ + L + WH C CA+CK+P + F+ D + YC+ DY LF+
Sbjct: 499 LCAKCNTKIMGEVMHALRQT-WHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFST 557
Query: 93 KCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCK 145
KC GC + + + A +H +CF C VC L+ G F K+ + LCK
Sbjct: 558 KCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLE-GQPFYSKKDRPLCK 609
Score = 70.1 bits (170), Expect = 3e-12
Identities = 40/122 (32%), Positives = 59/122 (48%), Gaps = 5/122 (4%)
Query: 28 AVSPKSVCEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLETTCFYRDK-KLYCKYDY 86
A S +C C VI FL+ + S WH + CA CK L CF ++ +YC+ Y
Sbjct: 434 ASSRTPLCGHCNNVIRGPFLVAMGRS-WHPEEFTCAYCKTSLADVCFVEEQNNVYCERCY 492
Query: 87 EKLFAVKCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKG 146
E+ FA C C I VM A + +H +CF C C++ F +++G+ C+
Sbjct: 493 EQFFAPLCAKCNTKIMGE--VMHALRQTWHTTCFVCAACKKPF-GNSLFHMEDGEPYCEK 549
Query: 147 DY 148
DY
Sbjct: 550 DY 551
>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
Length = 727
Score = 74.3 bits (181), Expect = 2e-13
Identities = 38/113 (33%), Positives = 57/113 (50%), Gaps = 3/113 (2%)
Query: 34 VCEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLETTCFY-RDKKLYCKYDYEKLFAV 92
+C C I+ + L + WH C CA+CK+P + F+ D + YC+ DY LF+
Sbjct: 609 LCAKCNTKIMGEVMHALRQT-WHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFST 667
Query: 93 KCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCK 145
KC GC + + + A +H +CF C VC L+ G F K+ + LCK
Sbjct: 668 KCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLE-GQPFYSKKDRPLCK 719
Score = 70.1 bits (170), Expect = 3e-12
Identities = 40/122 (32%), Positives = 59/122 (48%), Gaps = 5/122 (4%)
Query: 28 AVSPKSVCEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLETTCFYRDK-KLYCKYDY 86
A S +C C VI FL+ + S WH + CA CK L CF ++ +YC+ Y
Sbjct: 544 ASSRTPLCGHCNNVIRGPFLVAMGRS-WHPEEFTCAYCKTSLADVCFVEEQNNVYCERCY 602
Query: 87 EKLFAVKCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKG 146
E+ FA C C I VM A + +H +CF C C++ F +++G+ C+
Sbjct: 603 EQFFAPLCAKCNTKIMGE--VMHALRQTWHTTCFVCAACKKPF-GNSLFHMEDGEPYCEK 659
Query: 147 DY 148
DY
Sbjct: 660 DY 661
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.132 0.397
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,485,247
Number of Sequences: 37866
Number of extensions: 739742
Number of successful extensions: 5412
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 369
Number of HSP's successfully gapped in prelim test: 116
Number of HSP's that attempted gapping in prelim test: 3499
Number of HSP's gapped (non-prelim): 1131
length of query: 382
length of database: 18,247,518
effective HSP length: 104
effective length of query: 278
effective length of database: 14,309,454
effective search space: 3978028212
effective search space used: 3978028212
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.