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Search of human proteins with 27765078
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27765078 calpain 3 isoform e [Homo sapiens]
(156 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|47078247 calpain 3 isoform f [Homo sapiens] 329 5e-91
gi|4557405 calpain 3 isoform a [Homo sapiens] 329 5e-91
gi|27765072 calpain 3 isoform b [Homo sapiens] 329 5e-91
gi|27765080 calpain 3 isoform e [Homo sapiens] 329 5e-91
gi|27765078 calpain 3 isoform e [Homo sapiens] 329 5e-91
gi|27765076 calpain 3 isoform d [Homo sapiens] 329 5e-91
gi|27765074 calpain 3 isoform c [Homo sapiens] 329 5e-91
gi|4502565 calpain, small subunit 1 [Homo sapiens] 196 5e-51
gi|51599151 calpain, small subunit 1 [Homo sapiens] 196 5e-51
gi|12408656 calpain 1, large subunit [Homo sapiens] 189 8e-49
gi|14161692 calpain small subunit 2 [Homo sapiens] 188 2e-48
gi|157389005 calpain 2 isoform 1 [Homo sapiens] 159 9e-40
gi|225703100 calpain 2 isoform 2 [Homo sapiens] 159 9e-40
gi|215490104 calpain 11 [Homo sapiens] 159 9e-40
gi|7705383 calpain 9 isoform 2 [Homo sapiens] 150 3e-37
gi|5729758 calpain 9 isoform 1 [Homo sapiens] 150 3e-37
gi|221554549 calpain 8 [Homo sapiens] 141 2e-34
gi|38707981 calpain 12 [Homo sapiens] 100 9e-22
gi|223468608 calpain 14 [Homo sapiens] 95 3e-20
gi|38679884 sorcin isoform b [Homo sapiens] 92 2e-19
gi|4507207 sorcin isoform a [Homo sapiens] 92 2e-19
gi|41152101 calpain 13 [Homo sapiens] 91 5e-19
gi|6912388 grancalcin, EF-hand calcium binding protein [Homo sap... 86 1e-17
gi|7019485 programmed cell death 6 [Homo sapiens] 78 3e-15
gi|6912582 penta-EF-hand domain containing 1 [Homo sapiens] 76 1e-14
gi|223278387 calmodulin-like 5 [Homo sapiens] 49 2e-06
gi|58218968 calmodulin 3 [Homo sapiens] 42 2e-04
gi|4502549 calmodulin 2 [Homo sapiens] 42 2e-04
gi|5901912 calmodulin 1 [Homo sapiens] 42 2e-04
gi|110835715 calcyphosine-like [Homo sapiens] 42 3e-04
>gi|47078247 calpain 3 isoform f [Homo sapiens]
Length = 728
Score = 329 bits (844), Expect = 5e-91
Identities = 156/156 (100%), Positives = 156/156 (100%)
Query: 1 MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK 60
MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK
Sbjct: 573 MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK 632
Query: 61 AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC 120
AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC
Sbjct: 633 AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC 692
Query: 121 FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA 156
FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA
Sbjct: 693 FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA 728
>gi|4557405 calpain 3 isoform a [Homo sapiens]
Length = 821
Score = 329 bits (844), Expect = 5e-91
Identities = 156/156 (100%), Positives = 156/156 (100%)
Query: 1 MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK 60
MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK
Sbjct: 666 MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK 725
Query: 61 AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC 120
AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC
Sbjct: 726 AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC 785
Query: 121 FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA 156
FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA
Sbjct: 786 FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA 821
>gi|27765072 calpain 3 isoform b [Homo sapiens]
Length = 815
Score = 329 bits (844), Expect = 5e-91
Identities = 156/156 (100%), Positives = 156/156 (100%)
Query: 1 MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK 60
MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK
Sbjct: 660 MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK 719
Query: 61 AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC 120
AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC
Sbjct: 720 AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC 779
Query: 121 FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA 156
FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA
Sbjct: 780 FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA 815
>gi|27765080 calpain 3 isoform e [Homo sapiens]
Length = 156
Score = 329 bits (844), Expect = 5e-91
Identities = 156/156 (100%), Positives = 156/156 (100%)
Query: 1 MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK 60
MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK
Sbjct: 1 MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK 60
Query: 61 AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC 120
AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC
Sbjct: 61 AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC 120
Query: 121 FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA 156
FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA
Sbjct: 121 FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA 156
>gi|27765078 calpain 3 isoform e [Homo sapiens]
Length = 156
Score = 329 bits (844), Expect = 5e-91
Identities = 156/156 (100%), Positives = 156/156 (100%)
Query: 1 MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK 60
MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK
Sbjct: 1 MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK 60
Query: 61 AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC 120
AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC
Sbjct: 61 AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC 120
Query: 121 FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA 156
FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA
Sbjct: 121 FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA 156
>gi|27765076 calpain 3 isoform d [Homo sapiens]
Length = 309
Score = 329 bits (844), Expect = 5e-91
Identities = 156/156 (100%), Positives = 156/156 (100%)
Query: 1 MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK 60
MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK
Sbjct: 154 MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK 213
Query: 61 AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC 120
AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC
Sbjct: 214 AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC 273
Query: 121 FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA 156
FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA
Sbjct: 274 FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA 309
>gi|27765074 calpain 3 isoform c [Homo sapiens]
Length = 729
Score = 329 bits (844), Expect = 5e-91
Identities = 156/156 (100%), Positives = 156/156 (100%)
Query: 1 MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK 60
MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK
Sbjct: 574 MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK 633
Query: 61 AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC 120
AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC
Sbjct: 634 AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC 693
Query: 121 FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA 156
FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA
Sbjct: 694 FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA 729
>gi|4502565 calpain, small subunit 1 [Homo sapiens]
Length = 268
Score = 196 bits (499), Expect = 5e-51
Identities = 90/156 (57%), Positives = 118/156 (75%)
Query: 1 MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK 60
ME+ A EL +LN VV +H DLKT GF +++CRSM+A+MD+D +GKL +EF +LWN IK
Sbjct: 113 MEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIK 172
Query: 61 AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC 120
WQ I+K +DTD+SGTI S E+ A AGFHLN LY++I RY+D+ N+DFD+FI C
Sbjct: 173 RWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISC 232
Query: 121 FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA 156
VRL+ MFRAF + DKDG G I++N+ EWLQLTMY+
Sbjct: 233 LVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS 268
>gi|51599151 calpain, small subunit 1 [Homo sapiens]
Length = 268
Score = 196 bits (499), Expect = 5e-51
Identities = 90/156 (57%), Positives = 118/156 (75%)
Query: 1 MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK 60
ME+ A EL +LN VV +H DLKT GF +++CRSM+A+MD+D +GKL +EF +LWN IK
Sbjct: 113 MEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSDTTGKLGFEEFKYLWNNIK 172
Query: 61 AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC 120
WQ I+K +DTD+SGTI S E+ A AGFHLN LY++I RY+D+ N+DFD+FI C
Sbjct: 173 RWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNEHLYNMIIRRYSDESGNMDFDNFISC 232
Query: 121 FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA 156
VRL+ MFRAF + DKDG G I++N+ EWLQLTMY+
Sbjct: 233 LVRLDAMFRAFKSLDKDGTGQIQVNIQEWLQLTMYS 268
>gi|12408656 calpain 1, large subunit [Homo sapiens]
Length = 714
Score = 189 bits (480), Expect = 8e-49
Identities = 83/156 (53%), Positives = 119/156 (76%)
Query: 1 MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK 60
MEI EL+ +LN +++KHKDL+T GF+LESCRSM+ LMD DG+GKL L EF+ LWN+I+
Sbjct: 559 MEISVKELRTILNRIISKHKDLRTKGFSLESCRSMVNLMDRDGNGKLGLVEFNILWNRIR 618
Query: 61 AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC 120
+ IF+ +D D+SG++++YEMR A+ AGF LN +LY++I RY++ + +DFD+F+CC
Sbjct: 619 NYLSIFRKFDLDKSGSMSAYEMRMAIESAGFKLNKKLYELIITRYSEPDLAVDFDNFVCC 678
Query: 121 FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA 156
VRLE MFR F D D DG++ ++ +WLQLTM+A
Sbjct: 679 LVRLETMFRFFKTLDTDLDGVVTFDLFKWLQLTMFA 714
>gi|14161692 calpain small subunit 2 [Homo sapiens]
Length = 248
Score = 188 bits (477), Expect = 2e-48
Identities = 82/156 (52%), Positives = 121/156 (77%)
Query: 1 MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK 60
ME+ A +L +LN V++KHKDLKT GF+L++CRS++++MD+D +GKL +EF +LWN IK
Sbjct: 93 MEVGATDLMNILNKVLSKHKDLKTDGFSLDTCRSIVSVMDSDTTGKLGFEEFKYLWNNIK 152
Query: 61 AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC 120
WQ ++K YD D SG++ S ++R A+ AGF LN QLY +I RYA++ ++DF++FI C
Sbjct: 153 KWQCVYKQYDRDHSGSLGSSQLRGALQAAGFQLNEQLYQMIVRRYANEDGDMDFNNFISC 212
Query: 121 FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA 156
VRL+ MFRAF + D+D DG+I++++ EWLQLTMY+
Sbjct: 213 LVRLDAMFRAFKSLDRDRDGLIQVSIKEWLQLTMYS 248
>gi|157389005 calpain 2 isoform 1 [Homo sapiens]
Length = 700
Score = 159 bits (402), Expect = 9e-40
Identities = 71/149 (47%), Positives = 109/149 (73%)
Query: 2 EICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKA 61
EI A EL+ +L V+ K +D+K+ GF++E+C+ M+ ++D+DGSGKL L+EF+ LW KI+
Sbjct: 547 EISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQK 606
Query: 62 WQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICCF 121
+QKI++ D D+SGT+NSYEMR A+ +AGF + QL+ +I R+AD + IDFD+F+ C
Sbjct: 607 YQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFVRCL 666
Query: 122 VRLEGMFRAFHAFDKDGDGIIKLNVLEWL 150
VRLE +F+ F D + G I+L+++ WL
Sbjct: 667 VRLETLFKIFKQLDPENTGTIELDLISWL 695
>gi|225703100 calpain 2 isoform 2 [Homo sapiens]
Length = 622
Score = 159 bits (402), Expect = 9e-40
Identities = 71/149 (47%), Positives = 109/149 (73%)
Query: 2 EICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKA 61
EI A EL+ +L V+ K +D+K+ GF++E+C+ M+ ++D+DGSGKL L+EF+ LW KI+
Sbjct: 469 EISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYILWTKIQK 528
Query: 62 WQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICCF 121
+QKI++ D D+SGT+NSYEMR A+ +AGF + QL+ +I R+AD + IDFD+F+ C
Sbjct: 529 YQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFDNFVRCL 588
Query: 122 VRLEGMFRAFHAFDKDGDGIIKLNVLEWL 150
VRLE +F+ F D + G I+L+++ WL
Sbjct: 589 VRLETLFKIFKQLDPENTGTIELDLISWL 617
>gi|215490104 calpain 11 [Homo sapiens]
Length = 739
Score = 159 bits (402), Expect = 9e-40
Identities = 79/154 (51%), Positives = 101/154 (65%)
Query: 2 EICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKA 61
EI EL+++LN + K K KT GF L++CR MI LMD DGSGKL L EF LW K+K
Sbjct: 585 EIGVYELQRLLNRMAIKFKSFKTKGFGLDACRCMINLMDKDGSGKLGLLEFKILWKKLKK 644
Query: 62 WQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICCF 121
W IF+ D D SGT+NSYEMR + AG LNN++ ++ RYAD + IDFDSFI CF
Sbjct: 645 WMDIFRECDQDHSGTLNSYEMRLVIEKAGIKLNNKVMQVLVARYADDDLIIDFDSFISCF 704
Query: 122 VRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMY 155
+RL+ MF F D G I L++ +WLQ+TM+
Sbjct: 705 LRLKTMFTFFLTMDPKNTGHICLSLEQWLQMTMW 738
>gi|7705383 calpain 9 isoform 2 [Homo sapiens]
Length = 664
Score = 150 bits (380), Expect = 3e-37
Identities = 70/154 (45%), Positives = 102/154 (66%)
Query: 1 MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK 60
ME+ A+EL+ VLN V+ K KD+K +L SC+++I+LMDT G+GKL EF W+K+K
Sbjct: 509 MEVTAEELEYVLNAVLQKKKDIKFKKLSLISCKNIISLMDTSGNGKLEFDEFKVFWDKLK 568
Query: 61 AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC 120
W +F +D D+SGT+++YE+R A+ AGF L++ L +I +RYAD+ + +DFD F+ C
Sbjct: 569 QWINLFLRFDADKSGTMSTYELRTALKAAGFQLSSHLLQLIVLRYADEELQLDFDDFLNC 628
Query: 121 FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTM 154
VRLE R F A I LN+ E++ LTM
Sbjct: 629 LVRLENASRVFQALSTKNKEFIHLNINEFIHLTM 662
>gi|5729758 calpain 9 isoform 1 [Homo sapiens]
Length = 690
Score = 150 bits (380), Expect = 3e-37
Identities = 70/154 (45%), Positives = 102/154 (66%)
Query: 1 MEICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIK 60
ME+ A+EL+ VLN V+ K KD+K +L SC+++I+LMDT G+GKL EF W+K+K
Sbjct: 535 MEVTAEELEYVLNAVLQKKKDIKFKKLSLISCKNIISLMDTSGNGKLEFDEFKVFWDKLK 594
Query: 61 AWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICC 120
W +F +D D+SGT+++YE+R A+ AGF L++ L +I +RYAD+ + +DFD F+ C
Sbjct: 595 QWINLFLRFDADKSGTMSTYELRTALKAAGFQLSSHLLQLIVLRYADEELQLDFDDFLNC 654
Query: 121 FVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTM 154
VRLE R F A I LN+ E++ LTM
Sbjct: 655 LVRLENASRVFQALSTKNKEFIHLNINEFIHLTM 688
>gi|221554549 calpain 8 [Homo sapiens]
Length = 703
Score = 141 bits (356), Expect = 2e-34
Identities = 66/149 (44%), Positives = 101/149 (67%)
Query: 2 EICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKA 61
EI A+ LK +LN +K D+K GF + +CR MI+L+D++G+G L EF LW KI+
Sbjct: 550 EITANALKILLNEAFSKRTDIKFDGFNINTCREMISLLDSNGTGTLGAVEFKTLWLKIQK 609
Query: 62 WQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICCF 121
+ +I+ D + SGTI+++EMR A+ AGF LN+Q+ I +RYA + I+FDSF+ C
Sbjct: 610 YLEIYWETDYNHSGTIDAHEMRTALRKAGFTLNSQVQQTIALRYACSKLGINFDSFVACM 669
Query: 122 VRLEGMFRAFHAFDKDGDGIIKLNVLEWL 150
+RLE +F+ F D+D DG+++L++ EWL
Sbjct: 670 IRLETLFKLFSLLDEDKDGMVQLSLAEWL 698
>gi|38707981 calpain 12 [Homo sapiens]
Length = 719
Score = 99.8 bits (247), Expect = 9e-22
Identities = 49/125 (39%), Positives = 71/125 (56%), Gaps = 1/125 (0%)
Query: 33 RSMIALMDTDGSGK-LNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGF 91
R+ L+ G G+ L L F LW + WQ IF +D D SGT+NSYE+R A+N AGF
Sbjct: 595 RTCEQLLQCFGHGQSLALHHFQQLWGYLLEWQAIFNKFDEDTSGTMNSYELRLALNAAGF 654
Query: 92 HLNNQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQ 151
HLNNQL +T RY D + +DF+ F+ C L +F G+G+I L +W++
Sbjct: 655 HLNNQLTQTLTSRYRDSRLRVDFERFVSCVAHLTCIFCHCSQHLDGGEGVICLTHRQWME 714
Query: 152 LTMYA 156
+ ++
Sbjct: 715 VATFS 719
>gi|223468608 calpain 14 [Homo sapiens]
Length = 684
Score = 94.7 bits (234), Expect = 3e-20
Identities = 51/155 (32%), Positives = 89/155 (57%), Gaps = 2/155 (1%)
Query: 2 EICADELKKVLNTVVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKA 61
EI A +L+ +LN + + F+LE+C+ ++AL+D + SG +++QEF LW ++K
Sbjct: 532 EINAVQLQNLLNQMTWSSLGSRQPFFSLEACQGILALLDLNASGTMSIQEFRDLWKQLKL 591
Query: 62 WQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFICCF 121
QK+F H SG +N ++ A+ +AG L++ + ++ +RY + +DF SFI
Sbjct: 592 SQKVF-HKQDRGSGYLNWEQLHAAMREAGIMLSDDVCQLMLIRYGGPRLQMDFVSFIHLM 650
Query: 122 VRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTMYA 156
+R+E M F +DG GI L EW+ + +Y+
Sbjct: 651 LRVENMEDVFQNLTQDGKGIY-LQKPEWMMMALYS 684
>gi|38679884 sorcin isoform b [Homo sapiens]
Length = 183
Score = 92.0 bits (227), Expect = 2e-19
Identities = 50/155 (32%), Positives = 84/155 (54%), Gaps = 8/155 (5%)
Query: 2 EICADELKKVLNT--VVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKI 59
+I ADEL++ L + +K F LE+CR M++++D D SG + EF LW +
Sbjct: 33 QIDADELQRCLTQSGIAGGYKP-----FNLETCRLMVSMLDRDMSGTMGFNEFKELWAVL 87
Query: 60 KAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFIC 119
W++ F +DTD+SGT++ E++ A+ GF L+ Q + I RY+ + I FD +I
Sbjct: 88 NGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYS-TNGKITFDDYIA 146
Query: 120 CFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTM 154
C V+L + +F D G++ +++Q M
Sbjct: 147 CCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVM 181
>gi|4507207 sorcin isoform a [Homo sapiens]
Length = 198
Score = 92.0 bits (227), Expect = 2e-19
Identities = 50/155 (32%), Positives = 84/155 (54%), Gaps = 8/155 (5%)
Query: 2 EICADELKKVLNT--VVNKHKDLKTHGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKI 59
+I ADEL++ L + +K F LE+CR M++++D D SG + EF LW +
Sbjct: 48 QIDADELQRCLTQSGIAGGYKP-----FNLETCRLMVSMLDRDMSGTMGFNEFKELWAVL 102
Query: 60 KAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDIITMRYADKHMNIDFDSFIC 119
W++ F +DTD+SGT++ E++ A+ GF L+ Q + I RY+ + I FD +I
Sbjct: 103 NGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYS-TNGKITFDDYIA 161
Query: 120 CFVRLEGMFRAFHAFDKDGDGIIKLNVLEWLQLTM 154
C V+L + +F D G++ +++Q M
Sbjct: 162 CCVKLRALTDSFRRRDTAQQGVVNFPYDDFIQCVM 196
>gi|41152101 calpain 13 [Homo sapiens]
Length = 669
Score = 90.5 bits (223), Expect = 5e-19
Identities = 44/133 (33%), Positives = 77/133 (57%), Gaps = 6/133 (4%)
Query: 27 FTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAV 86
F+L+ CRS++ALM+ +G+L+ +EF LW ++ +Q +F+ T G + S ++ A+
Sbjct: 538 FSLDECRSLVALMELKVNGRLDQEEFARLWKRLVHYQHVFQKVQTSP-GVLLSSDLWKAI 596
Query: 87 NDA----GFHLNNQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGII 142
+ G ++ +L ++T+RY+D + F S +C +RLE M + F KDG G+
Sbjct: 597 ENTDFLRGIFISRELLHLVTLRYSDSVGRVSFPSLVCFLMRLEAMAKTFRNLSKDGKGLY 656
Query: 143 KLNVLEWLQLTMY 155
L +EW+ L MY
Sbjct: 657 -LTEMEWMSLVMY 668
>gi|6912388 grancalcin, EF-hand calcium binding protein [Homo
sapiens]
Length = 217
Score = 85.9 bits (211), Expect = 1e-17
Identities = 46/128 (35%), Positives = 69/128 (53%), Gaps = 1/128 (0%)
Query: 27 FTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAV 86
F+LE+CR MIA++D D +GK+ F LW + AW++ F D D SGT+ +E+R A+
Sbjct: 89 FSLETCRIMIAMLDRDHTGKMGFNAFKELWAALNAWKENFMTVDQDGSGTVEHHELRQAI 148
Query: 87 NDAGFHLNNQLYDIITMRYADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNV 146
G+ L+ Q I RY+ K+ I FD ++ C V+L + F D G
Sbjct: 149 GLMGYRLSPQTLTTIVKRYS-KNGRIFFDDYVACCVKLRALTDFFRKRDHLQQGSANFIY 207
Query: 147 LEWLQLTM 154
++LQ TM
Sbjct: 208 DDFLQGTM 215
>gi|7019485 programmed cell death 6 [Homo sapiens]
Length = 191
Score = 77.8 bits (190), Expect = 3e-15
Identities = 39/127 (30%), Positives = 70/127 (55%), Gaps = 1/127 (0%)
Query: 27 FTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAV 86
F + RS+I++ D + +N EF +W I WQ +F+ YD D SG I+ E++ A+
Sbjct: 60 FNPVTVRSIISMFDRENKAGVNFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELKQAL 119
Query: 87 NDAGFHLNNQLYDIITMRY-ADKHMNIDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLN 145
+ G+ L++Q +DI+ ++ I FD FI + L+ + F +D D DG I+++
Sbjct: 120 SGFGYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTDIFRRYDTDQDGWIQVS 179
Query: 146 VLEWLQL 152
++L +
Sbjct: 180 YEQYLSM 186
Score = 37.4 bits (85), Expect = 0.005
Identities = 24/96 (25%), Positives = 45/96 (46%), Gaps = 9/96 (9%)
Query: 55 LWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNN--QLYDIITMRYADKHMNI 112
LWN +F+ D D+SG I+ E++ A+++ + N + II+M + +
Sbjct: 28 LWN-------VFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGV 80
Query: 113 DFDSFICCFVRLEGMFRAFHAFDKDGDGIIKLNVLE 148
+F F + + F +D+D G+I N L+
Sbjct: 81 NFSEFTGVWKYITDWQNVFRTYDRDNSGMIDKNELK 116
>gi|6912582 penta-EF-hand domain containing 1 [Homo sapiens]
Length = 284
Score = 75.9 bits (185), Expect = 1e-14
Identities = 39/129 (30%), Positives = 72/129 (55%), Gaps = 2/129 (1%)
Query: 27 FTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAV 86
F E+C MI + D SG++++ F LW I+ W+ +F+ YD D+SG+I+ E++ A+
Sbjct: 151 FNDETCLMMINMFDKTKSGRIDVYGFSALWKFIQQWKNLFQQYDRDRSGSISYTELQQAL 210
Query: 87 NDAGFHLNNQLYDIITMRYADKHMN--IDFDSFICCFVRLEGMFRAFHAFDKDGDGIIKL 144
+ G++L+ Q ++ RY + N + D FI +L+ + AF D G I+L
Sbjct: 211 SQMGYNLSPQFTQLLVSRYCPRSANPAMQLDRFIQVCTQLQVLTEAFREKDTAVQGNIRL 270
Query: 145 NVLEWLQLT 153
+ +++ +T
Sbjct: 271 SFEDFVTMT 279
>gi|223278387 calmodulin-like 5 [Homo sapiens]
Length = 146
Score = 48.9 bits (115), Expect = 2e-06
Identities = 33/91 (36%), Positives = 50/91 (54%), Gaps = 5/91 (5%)
Query: 62 WQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNN-QLYDIITMRYADKHMNIDFDSFICC 120
++K F DTD +GTIN+ E+ A+ G +L+ QL +I+ +D I F F+
Sbjct: 13 YKKAFSAVDTDGNGTINAQELGAALKATGKNLSEAQLRKLISEVDSDGDGEISFQEFLTA 72
Query: 121 FVR----LEGMFRAFHAFDKDGDGIIKLNVL 147
+ LE + AF AFD+DGDG I ++ L
Sbjct: 73 AKKARAGLEDLQVAFRAFDQDGDGHITVDEL 103
Score = 38.1 bits (87), Expect = 0.003
Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 7/103 (6%)
Query: 22 LKTHGFTLESC--RSMIALMDTDGSGKLNLQEFHHLWNKIKA----WQKIFKHYDTDQSG 75
LK G L R +I+ +D+DG G+++ QEF K +A Q F+ +D D G
Sbjct: 37 LKATGKNLSEAQLRKLISEVDSDGDGEISFQEFLTAAKKARAGLEDLQVAFRAFDQDGDG 96
Query: 76 TINSYEMRNAVNDAGFHLNNQLYD-IITMRYADKHMNIDFDSF 117
I E+R A+ G L + D +I D+ ++++ F
Sbjct: 97 HITVDELRRAMAGLGQPLPQEELDAMIREADVDQDGRVNYEEF 139
>gi|58218968 calmodulin 3 [Homo sapiens]
Length = 149
Score = 42.4 bits (98), Expect = 2e-04
Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 8/93 (8%)
Query: 58 KIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNN-QLYDIITMRYADKHMNIDFDS 116
+I +++ F +D D GTI + E+ + G + +L D+I AD + IDF
Sbjct: 9 QIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPE 68
Query: 117 FICCFVRL-------EGMFRAFHAFDKDGDGII 142
F+ R E + AF FDKDG+G I
Sbjct: 69 FLTMMARKMKDTDSEEEIREAFRVFDKDGNGYI 101
Score = 32.3 bits (72), Expect = 0.17
Identities = 23/94 (24%), Positives = 49/94 (52%), Gaps = 8/94 (8%)
Query: 33 RSMIALMDTDGSGKLNLQEFHHLW-NKIKAW------QKIFKHYDTDQSGTINSYEMRNA 85
+ MI +D DG+G ++ EF + K+K ++ F+ +D D +G I++ E+R+
Sbjct: 50 QDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHV 109
Query: 86 VNDAGFHLNNQLYD-IITMRYADKHMNIDFDSFI 118
+ + G L ++ D +I D ++++ F+
Sbjct: 110 MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143
>gi|4502549 calmodulin 2 [Homo sapiens]
Length = 149
Score = 42.4 bits (98), Expect = 2e-04
Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 8/93 (8%)
Query: 58 KIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNN-QLYDIITMRYADKHMNIDFDS 116
+I +++ F +D D GTI + E+ + G + +L D+I AD + IDF
Sbjct: 9 QIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPE 68
Query: 117 FICCFVRL-------EGMFRAFHAFDKDGDGII 142
F+ R E + AF FDKDG+G I
Sbjct: 69 FLTMMARKMKDTDSEEEIREAFRVFDKDGNGYI 101
Score = 32.3 bits (72), Expect = 0.17
Identities = 23/94 (24%), Positives = 49/94 (52%), Gaps = 8/94 (8%)
Query: 33 RSMIALMDTDGSGKLNLQEFHHLW-NKIKAW------QKIFKHYDTDQSGTINSYEMRNA 85
+ MI +D DG+G ++ EF + K+K ++ F+ +D D +G I++ E+R+
Sbjct: 50 QDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHV 109
Query: 86 VNDAGFHLNNQLYD-IITMRYADKHMNIDFDSFI 118
+ + G L ++ D +I D ++++ F+
Sbjct: 110 MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143
>gi|5901912 calmodulin 1 [Homo sapiens]
Length = 149
Score = 42.4 bits (98), Expect = 2e-04
Identities = 29/93 (31%), Positives = 44/93 (47%), Gaps = 8/93 (8%)
Query: 58 KIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNN-QLYDIITMRYADKHMNIDFDS 116
+I +++ F +D D GTI + E+ + G + +L D+I AD + IDF
Sbjct: 9 QIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPE 68
Query: 117 FICCFVRL-------EGMFRAFHAFDKDGDGII 142
F+ R E + AF FDKDG+G I
Sbjct: 69 FLTMMARKMKDTDSEEEIREAFRVFDKDGNGYI 101
Score = 32.3 bits (72), Expect = 0.17
Identities = 23/94 (24%), Positives = 49/94 (52%), Gaps = 8/94 (8%)
Query: 33 RSMIALMDTDGSGKLNLQEFHHLW-NKIKAW------QKIFKHYDTDQSGTINSYEMRNA 85
+ MI +D DG+G ++ EF + K+K ++ F+ +D D +G I++ E+R+
Sbjct: 50 QDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHV 109
Query: 86 VNDAGFHLNNQLYD-IITMRYADKHMNIDFDSFI 118
+ + G L ++ D +I D ++++ F+
Sbjct: 110 MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFV 143
>gi|110835715 calcyphosine-like [Homo sapiens]
Length = 208
Score = 41.6 bits (96), Expect = 3e-04
Identities = 31/114 (27%), Positives = 51/114 (44%), Gaps = 7/114 (6%)
Query: 41 TDGSGKLNLQEFHHLWNKIKAWQKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNNQLYDI 100
TD +L LQ IK ++F+ D D + T++ E +ND + + +
Sbjct: 23 TDPIERLRLQCLARGSAGIKGLGRVFRIMDDDNNRTLDFKEFMKGLNDYAVVMEKEEVEE 82
Query: 101 ITMRY-ADKHMNIDFDSFICCF------VRLEGMFRAFHAFDKDGDGIIKLNVL 147
+ R+ D + IDF+ F+ R E + +AF DK GDG+I + L
Sbjct: 83 LFRRFDKDGNGTIDFNEFLLTLRPPMSRARKEVIMQAFRKLDKTGDGVITIEDL 136
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.138 0.433
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 5,591,752
Number of Sequences: 37866
Number of extensions: 214303
Number of successful extensions: 891
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 49
Number of HSP's successfully gapped in prelim test: 52
Number of HSP's that attempted gapping in prelim test: 738
Number of HSP's gapped (non-prelim): 185
length of query: 156
length of database: 18,247,518
effective HSP length: 94
effective length of query: 62
effective length of database: 14,688,114
effective search space: 910663068
effective search space used: 910663068
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 57 (26.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.