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Search of human proteins with 253970504
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo
sapiens]
(600 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo s... 1283 0.0
gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo sap... 1244 0.0
gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo s... 1238 0.0
gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo s... 1232 0.0
gi|253970506 Ewing sarcoma breakpoint region 1 isoform 5 [Homo s... 525 e-149
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 464 e-130
gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens] 356 4e-98
gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens] 355 5e-98
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 105 1e-22
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 93 6e-19
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 91 3e-18
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 90 5e-18
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 90 5e-18
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 90 5e-18
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 90 7e-18
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 90 7e-18
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 90 7e-18
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 88 2e-17
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 88 3e-17
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 87 4e-17
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 87 6e-17
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 84 3e-16
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 84 3e-16
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s... 83 6e-16
gi|48762934 alpha 2 type I collagen [Homo sapiens] 82 1e-15
gi|153252068 testes-specific heterogenous nuclear ribonucleoprot... 82 1e-15
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 81 2e-15
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s... 81 2e-15
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 81 2e-15
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 81 2e-15
>gi|253970504 Ewing sarcoma breakpoint region 1 isoform 4 [Homo
sapiens]
Length = 600
Score = 1283 bits (3319), Expect = 0.0
Identities = 600/600 (100%), Positives = 600/600 (100%)
Query: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 60
MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT
Sbjct: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 60
Query: 61 YGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT 120
YGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT
Sbjct: 61 YGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT 120
Query: 121 QPAYPAYGQQPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQP 180
QPAYPAYGQQPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQP
Sbjct: 121 QPAYPAYGQQPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQP 180
Query: 181 PTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSG 240
PTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSG
Sbjct: 181 PTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSG 240
Query: 241 PDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDE 300
PDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDE
Sbjct: 241 PDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDE 300
Query: 301 DSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVS 360
DSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVS
Sbjct: 301 DSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVS 360
Query: 361 YEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGG 420
YEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGG
Sbjct: 361 YEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGG 420
Query: 421 PGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAW 480
PGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAW
Sbjct: 421 PGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAW 480
Query: 481 RTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDR 540
RTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDR
Sbjct: 481 RTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDR 540
Query: 541 GGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY 600
GGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY
Sbjct: 541 GGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY 600
>gi|4885225 Ewing sarcoma breakpoint region 1 isoform 2 [Homo
sapiens]
Length = 656
Score = 1244 bits (3220), Expect = 0.0
Identities = 595/656 (90%), Positives = 597/656 (91%), Gaps = 56/656 (8%)
Query: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 60
MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT
Sbjct: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 60
Query: 61 YGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT 120
YGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT
Sbjct: 61 YGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT 120
Query: 121 QPAYPAY--------------GQQPAATA------------------------------- 135
QPAYPAY G +P T+
Sbjct: 121 QPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYP 180
Query: 136 -----------PTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY 184
PTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY
Sbjct: 181 MQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY 240
Query: 185 PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR 244
PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR
Sbjct: 241 PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR 300
Query: 245 GRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN 304
GRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN
Sbjct: 301 GRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN 360
Query: 305 SAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDP 364
SAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDP
Sbjct: 361 SAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDP 420
Query: 365 PTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGP 424
PTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGP
Sbjct: 421 PTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGP 480
Query: 425 GGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTEC 484
GGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTEC
Sbjct: 481 GGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTEC 540
Query: 485 NQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFR 544
NQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFR
Sbjct: 541 NQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFR 600
Query: 545 GGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY 600
GGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY
Sbjct: 601 GGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY 656
>gi|253970502 Ewing sarcoma breakpoint region 1 isoform 3 [Homo
sapiens]
Length = 655
Score = 1238 bits (3204), Expect = 0.0
Identities = 594/656 (90%), Positives = 596/656 (90%), Gaps = 57/656 (8%)
Query: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 60
MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT
Sbjct: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 60
Query: 61 YGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT 120
YGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT
Sbjct: 61 YGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT 120
Query: 121 QPAYPAY--------------GQQPAATA------------------------------- 135
QPAYPAY G +P T+
Sbjct: 121 QPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYP 180
Query: 136 -----------PTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY 184
PTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY
Sbjct: 181 MQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY 240
Query: 185 PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR 244
PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR
Sbjct: 241 PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR 300
Query: 245 GRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN 304
GRGRGGFDRGGMSRGGRGGGRGGMG AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN
Sbjct: 301 GRGRGGFDRGGMSRGGRGGGRGGMG-AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN 359
Query: 305 SAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDP 364
SAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDP
Sbjct: 360 SAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDP 419
Query: 365 PTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGP 424
PTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGP
Sbjct: 420 PTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGP 479
Query: 425 GGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTEC 484
GGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTEC
Sbjct: 480 GGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTEC 539
Query: 485 NQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFR 544
NQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFR
Sbjct: 540 NQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFR 599
Query: 545 GGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY 600
GGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY
Sbjct: 600 GGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY 655
>gi|253970500 Ewing sarcoma breakpoint region 1 isoform 1 [Homo
sapiens]
Length = 661
Score = 1232 bits (3187), Expect = 0.0
Identities = 594/662 (89%), Positives = 596/662 (90%), Gaps = 63/662 (9%)
Query: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 60
MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT
Sbjct: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 60
Query: 61 YGQTAYATSYGQPPT------GYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAA 114
YGQTAYATSYGQPPT GYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAA
Sbjct: 61 YGQTAYATSYGQPPTVEGTSTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAA 120
Query: 115 QSAYGTQPAYPAY--------------GQQPAATA------------------------- 135
QSAYGTQPAYPAY G +P T+
Sbjct: 121 QSAYGTQPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQ 180
Query: 136 -----------------PTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQ 178
PTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQ
Sbjct: 181 VPGSYPMQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQ 240
Query: 179 QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSM 238
QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSM
Sbjct: 241 QPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSM 300
Query: 239 SGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDP 298
SGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG AGERGGFNKPGGPMDEGPDLDLGPPVDP
Sbjct: 301 SGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG-AGERGGFNKPGGPMDEGPDLDLGPPVDP 359
Query: 299 DEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDAT 358
DEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDAT
Sbjct: 360 DEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDAT 419
Query: 359 VSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGP 418
VSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGP
Sbjct: 420 VSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGP 479
Query: 419 GGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNF 478
GGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNF
Sbjct: 480 GGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNF 539
Query: 479 AWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGG 538
AWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGG
Sbjct: 540 AWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGG 599
Query: 539 DRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDR 598
DRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDR
Sbjct: 600 DRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDR 659
Query: 599 PY 600
PY
Sbjct: 660 PY 661
>gi|253970506 Ewing sarcoma breakpoint region 1 isoform 5 [Homo
sapiens]
Length = 354
Score = 525 bits (1351), Expect = e-149
Identities = 268/329 (81%), Positives = 268/329 (81%), Gaps = 56/329 (17%)
Query: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 60
MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT
Sbjct: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT 60
Query: 61 YGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT 120
YGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT
Sbjct: 61 YGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGT 120
Query: 121 QPAYPAYGQQPAATAPT------------------------------------------- 137
QPAYPAYGQQPAATAPT
Sbjct: 121 QPAYPAYGQQPAATAPTRPQDGNKPTETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYP 180
Query: 138 --------SYSST-----QPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY 184
SY T QPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY
Sbjct: 181 MQPVTAPPSYPPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY 240
Query: 185 PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR 244
PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR
Sbjct: 241 PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR 300
Query: 245 GRGRGGFDRGGMSRGGRGGGRGGMGSAGE 273
GRGRGGFDRGGMSRGGRGGGRGGMG E
Sbjct: 301 GRGRGGFDRGGMSRGGRGGGRGGMGLQSE 329
Score = 53.1 bits (126), Expect = 7e-07
Identities = 98/373 (26%), Positives = 138/373 (36%), Gaps = 75/373 (20%)
Query: 112 YAAQSAYGTQPAYPAYGQQPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPS--SYGQQ-- 167
Y+ S Q Y AY QP Y+ T +Y Q SY TYGQP+ SY Q
Sbjct: 6 YSTYSQAAAQQGYSAYTAQPTQ----GYAQTTQ-AYGQQSYG---TYGQPTDVSYTQAQT 57
Query: 168 -SSYGQQS---SYGQQPPTSYP----PQ----------TGSYSQAPSQYSQQSSSYGQQS 209
++YGQ + SYGQ PPT Y PQ TG+Y + + +SY QS
Sbjct: 58 TATYGQTAYATSYGQ-PPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQS 116
Query: 210 SFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG 269
++ + YGQ+ + P + + P + + GG ++ G G+
Sbjct: 117 AYGTQ--PAYPAYGQQPAA-TAPTRPQDGNKPTETSQPQSS--TGGYNQPSLGYGQSNYS 171
Query: 270 SAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQG-LNDSVTLDDLADFFKQC 328
G + P P+ P PP S Y Q + T + + +Q
Sbjct: 172 YPQVPGSY--PMQPVTAPPSY---PPTSYSSTQPTS--YDQSSYSQQNTYGQPSSYGQQS 224
Query: 329 GVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSL 388
+ + QP T P T SY P+ + Q S
Sbjct: 225 SYGQQSSYGQQP--------PTSYPP--QTGSYSQAPSQYSQ---------QSSSYGQQS 265
Query: 389 ARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGG-DRGGFPPRGPR 447
+ ++ +SM G+ +E G GPG GP R GRGG DRGG R
Sbjct: 266 SFRQDHPSSM--GVYGQESGGF-----SGPGENRSMSGPDNRGRGRGGFDRGGM----SR 314
Query: 448 GSRGNPSGGGNVQ 460
G RG GG +Q
Sbjct: 315 GGRGGGRGGMGLQ 327
Score = 42.7 bits (99), Expect = 0.001
Identities = 24/43 (55%), Positives = 25/43 (58%), Gaps = 4/43 (9%)
Query: 500 FPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGG 542
F PG +R GP GRGG DR GGM RGGRGG RGG
Sbjct: 285 FSGPGENRSMSGPDNRGRGRGG-FDR---GGMSRGGRGGGRGG 323
Score = 36.2 bits (82), Expect = 0.089
Identities = 22/47 (46%), Positives = 22/47 (46%), Gaps = 1/47 (2%)
Query: 510 GGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGF-RGGRGMDRGGFG 555
G G G G GP RG G DRGG RGGRG RGG G
Sbjct: 279 GQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMG 325
Score = 30.8 bits (68), Expect = 3.7
Identities = 24/52 (46%), Positives = 27/52 (51%), Gaps = 3/52 (5%)
Query: 534 GGRGGDRGGFRGGRGMDRGGFGGGRRG-GPGGPPGPLMEQMGGRRGGRGGPG 584
G G + GGF G G +R G RG G GG M + GGR GGRGG G
Sbjct: 276 GVYGQESGGF-SGPGENRSMSGPDNRGRGRGGFDRGGMSR-GGRGGGRGGMG 325
Score = 30.4 bits (67), Expect = 4.9
Identities = 21/39 (53%), Positives = 21/39 (53%), Gaps = 3/39 (7%)
Query: 527 GPGGMFRGGRGGDRGGFRGGRGMDRGGFG-GGRRGGPGG 564
GPG R G D G RG G DRGG GGR GG GG
Sbjct: 287 GPGEN-RSMSGPDNRG-RGRGGFDRGGMSRGGRGGGRGG 323
>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
[Homo sapiens]
Length = 526
Score = 464 bits (1193), Expect = e-130
Identities = 297/623 (47%), Positives = 359/623 (57%), Gaps = 120/623 (19%)
Query: 1 MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQ-TTQAYGQQSYGTYGQPTDVSYTQAQTTA 59
MAS DY+ A Q Y AY QP QGY+Q ++Q YGQQSY Y Q TD T+
Sbjct: 1 MASNDYTQQ----ATQSYGAYPTQPGQGYSQQSSQPYGQQSYSGYSQSTD--------TS 48
Query: 60 TYGQTAYATSYGQPP-TGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAY 118
YGQ++Y+ SYGQ TGY T + PQ Y GYG +S ++QS+Y
Sbjct: 49 GYGQSSYS-SYGQSQNTGYGTQSTPQGYGS-TGGYG---------------SSQSSQSSY 91
Query: 119 GTQPAYPAYGQQPA--ATAPTSYSSTQPTSYDQ---SSYSQQNTY-GQPSSYGQQSSYGQ 172
G Q +YP YGQQPA +T+ + SS+Q +SY Q SYSQQ +Y GQ SYGQQ SY
Sbjct: 92 GQQSSYPGYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNP 151
Query: 173 QSSYGQQPPTSYPPQT---------GSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYG 223
YGQQ Y + G+Y Q S S S G + Q G YG
Sbjct: 152 PQGYGQQ--NQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYG 209
Query: 224 QESGGFSGPGENRSMSGPDNRGRGRGGFDR--GGMSRGGRGGGRGGMGSAG--ERGGFNK 279
Q+ G G R SG G G GG++R GG GRGGGRGG G G +RGGFNK
Sbjct: 210 QQDRG----GRGRGGSG-GGGGGGGGGYNRSSGGYEPRGRGGGRGGRGGMGGSDRGGFNK 264
Query: 280 PGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQ 339
GGP D+G D ++SDN+ I+VQGL ++VT++ +AD+FKQ G++K NK+TGQ
Sbjct: 265 FGGPRDQGSRHD-----SEQDNSDNNTIFVQGLGENVTIESVADYFKQIGIIKTNKKTGQ 319
Query: 340 PMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMR 399
PMI++Y D+ETGK KG+ATVS++DPP+AKAA++WFDGK+F G+ +KVS A ++ N R
Sbjct: 320 PMINLYTDRETGKLKGEATVSFDDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFN--R 377
Query: 400 GGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNV 459
GG R GRG RGGP G GG GG G GG RGGFP G GGG
Sbjct: 378 GGGNGRGGRG-----RGGPMGRGGYGGG----GSGGGGRGGFPSGG---------GGGGG 419
Query: 460 QHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGR 519
Q RAGDW+CPNP C N NF+WR ECNQCKAPKP+G PG GGPGG G
Sbjct: 420 QQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDG--------PG-----GGPGGSHMG- 465
Query: 520 GGLMDRGGPGGMFRGGRGG-DRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRG 578
G G RGGRGG DRGG+R GRG DRGGF GGR GG RG
Sbjct: 466 ------GNYGDDRRGGRGGYDRGGYR-GRGGDRGGFRGGRGGGD--------------RG 504
Query: 579 GRGGPGKMD-KGEHRQERRDRPY 600
G GPGKMD +GEHRQ+RR+RPY
Sbjct: 505 G-FGPGKMDSRGEHRQDRRERPY 526
>gi|4507353 TBP-associated factor 15 isoform 2 [Homo sapiens]
Length = 589
Score = 356 bits (913), Expect = 4e-98
Identities = 242/571 (42%), Positives = 299/571 (52%), Gaps = 110/571 (19%)
Query: 38 QQSYGTYGQPTDVSYTQA-QTTATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGTG 96
QQSY TYG P Y QA Q+ + YGQT +SYGQ +GY++ Q+YSQ GY
Sbjct: 14 QQSYSTYGNPGSQGYGQASQSYSGYGQTT-DSSYGQNYSGYSS--YGQSYSQSYGGYEN- 69
Query: 97 AYDTTTATVTTTQASYAAQSAYGTQPAYPAYGQQPAATAPTSYSSTQPTSYDQSSYSQQN 156
QS+Y QP Y GQQ + S P SYDQ Y QQ+
Sbjct: 70 ----------------QKQSSYSQQP-YNNQGQQQNMESSGSQGGRAP-SYDQPDYGQQD 111
Query: 157 TYGQPSSYGQ-QSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDH 215
+Y Q S Y Q Q SY +QS+Y QQ SYSQ Y Q +Y + QD
Sbjct: 112 SYDQQSGYDQHQGSYDEQSNYDQQHD--------SYSQNQQSYHSQRENYSHHT---QDD 160
Query: 216 PSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERG 275
+ YG+++ G+ G S G GRGRGG+D+ G RG G GG +RG
Sbjct: 161 RRDVSRYGEDNRGYGG-----SQGG----GRGRGGYDKDG--RGPMTGSSGG-----DRG 204
Query: 276 GFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNK 335
GF GG D GP D D +SDN+ I+VQGL + V+ D + +FFKQ G++K NK
Sbjct: 205 GFKNFGGHRDYGPRTDADSESD---NSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKTNK 261
Query: 336 RTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPM 395
+TG+PMI++Y DK+TGKPKG+ATVS++DPP+AKAA++WFDGK+F G+ +KVS A ++P
Sbjct: 262 KTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRPEF 321
Query: 396 NSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSG 455
MRGG G GG GR G RG RGGF RG G+P
Sbjct: 322 --MRGG--------------------GSGGGRRGRGGYRG--RGGFQGRG-----GDP-- 350
Query: 456 GGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPP-------PFPPPGGDRG 508
++GDW CPNP CGN NFA R CNQC P+PE P + G RG
Sbjct: 351 ------KSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGYRG 404
Query: 509 RGGPGGMRGGRGGLMDRGGPGG--MFRGGRGGDRGGFRGGRGMDR--GGFGGGRRGGPGG 564
RGG GG RGG GG GG GG GG GDR G GG G DR GG+GG R GG GG
Sbjct: 405 RGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSG--GGYGGDRSGGGYGGDRGGGYGG 462
Query: 565 PPGPLMEQMGGRRGGRGGPGKMDKGEHRQER 595
G GG G RGG D+G + +R
Sbjct: 463 DRG------GGYGGDRGGGYGGDRGGYGGDR 487
Score = 81.3 bits (199), Expect = 2e-15
Identities = 75/201 (37%), Positives = 82/201 (40%), Gaps = 61/201 (30%)
Query: 400 GGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNV 459
GG G G GG GG G GG G GG GGDRGG G RG G GG
Sbjct: 450 GGYGGDRGGGYGGDRGGGYGGDRG-GGYGGDRGGYGGDRGG-GYGGDRGGYGGDRGG--- 504
Query: 460 QHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGR 519
GD G G + GGDR RGG GG RGG
Sbjct: 505 --YGGD----RGGYGGDRGGY-----------------------GGDRSRGGYGGDRGGG 535
Query: 520 GGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGG 579
G GG GG GGDR G GG G DRGG GG RGG GG +MGGR
Sbjct: 536 SGY------GGDRSGGYGGDRSG--GGYGGDRGGGYGGDRGGYGG-------KMGGR--- 577
Query: 580 RGGPGKMDKGEHRQERRDRPY 600
++R ++R+RPY
Sbjct: 578 ---------NDYRNDQRNRPY 589
Score = 54.7 bits (130), Expect = 2e-07
Identities = 55/164 (33%), Positives = 62/164 (37%), Gaps = 55/164 (33%)
Query: 399 RGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGN 458
RGG G G RGG GG G G G GG GGDRGG+ RG G GGG+
Sbjct: 480 RGGYGGDRGGGYGGD-RGGYGGDRGGYG--GDRGGYGGDRGGYGGDRSRGGYGGDRGGGS 536
Query: 459 VQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGG 518
G+ GGDR GG GG R G
Sbjct: 537 -----------------------------------GY--------GGDRS-GGYGGDRSG 552
Query: 519 RGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGP 562
GG GG GG GGDRGG+ GG+ R + +R P
Sbjct: 553 -------GGYGGDRGGGYGGDRGGY-GGKMGGRNDYRNDQRNRP 588
Score = 49.3 bits (116), Expect = 1e-05
Identities = 38/105 (36%), Positives = 44/105 (41%), Gaps = 5/105 (4%)
Query: 171 GQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYG-QQSSFRQDHPSSMGVYGQESGGF 229
G + YG Y G Y Y YG + + D S G YG + GG
Sbjct: 478 GDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDR--SRGGYGGDRGGG 535
Query: 230 SGPGENRSMS-GPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGE 273
SG G +RS G D G G GG DRGG G RGG G MG +
Sbjct: 536 SGYGGDRSGGYGGDRSGGGYGG-DRGGGYGGDRGGYGGKMGGRND 579
Score = 47.8 bits (112), Expect = 3e-05
Identities = 39/116 (33%), Positives = 44/116 (37%), Gaps = 10/116 (8%)
Query: 176 YGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGE 234
YG Y G Y Y YG R + G YG + GG+ G
Sbjct: 468 YGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGD---RGGYGGDRGGYGGDRGGYGGDRS 524
Query: 235 NRSMSGPDNRGRGRGGFDRGG----MSRGGRGGGRGGMGSAGERGGF-NKPGGPMD 285
G G G GG GG S GG GG RGG G G+RGG+ K GG D
Sbjct: 525 RGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGG-GYGGDRGGYGGKMGGRND 579
Score = 45.8 bits (107), Expect = 1e-04
Identities = 35/70 (50%), Positives = 39/70 (55%), Gaps = 11/70 (15%)
Query: 220 GVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMS--RGGRGGGRGGMGSAGERGGF 277
G YG + GG G G +R G D RG G GG DRGG RGG GG RGG G G+RGG+
Sbjct: 466 GGYGGDRGG--GYGGDRGGYGGD-RGGGYGG-DRGGYGGDRGGYGGDRGGYG--GDRGGY 519
Query: 278 NKPGGPMDEG 287
GG G
Sbjct: 520 ---GGDRSRG 526
Score = 44.3 bits (103), Expect = 3e-04
Identities = 38/88 (43%), Positives = 42/88 (47%), Gaps = 11/88 (12%)
Query: 198 YSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGM- 256
Y SS G S R S G G SGG G G +R +RG G GG DRGG
Sbjct: 424 YGGDRSSGGGYSGDR----SGGGYGGDRSGG--GYGGDRGGGYGGDRGGGYGG-DRGGGY 476
Query: 257 --SRGGRGGGRGGMGSAGERGGFNKPGG 282
RGG GG RGG G G+RGG+ G
Sbjct: 477 GGDRGGYGGDRGG-GYGGDRGGYGGDRG 503
Score = 43.5 bits (101), Expect = 6e-04
Identities = 31/74 (41%), Positives = 37/74 (50%), Gaps = 8/74 (10%)
Query: 220 GVYGQESGGFSGPGENRSMSGPDNRGRG--RGGF--DRGGMS--RGGRGGGRGGMGSAGE 273
G YG + GG+ G + G D G G RGG+ DRGG RGG GG R G G+
Sbjct: 474 GGYGGDRGGYGG--DRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGD 531
Query: 274 RGGFNKPGGPMDEG 287
RGG + GG G
Sbjct: 532 RGGGSGYGGDRSGG 545
Score = 42.7 bits (99), Expect = 0.001
Identities = 31/71 (43%), Positives = 35/71 (49%), Gaps = 8/71 (11%)
Query: 218 SMGVYGQE---SGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRG---GMGSA 271
S G YG + GG+SG G D G G GG DRGG G RGGG G G G
Sbjct: 420 SGGGYGGDRSSGGGYSGDRSGGGYGG-DRSGGGYGG-DRGGGYGGDRGGGYGGDRGGGYG 477
Query: 272 GERGGFNKPGG 282
G+RGG+ G
Sbjct: 478 GDRGGYGGDRG 488
Score = 42.4 bits (98), Expect = 0.001
Identities = 31/68 (45%), Positives = 36/68 (52%), Gaps = 8/68 (11%)
Query: 218 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSR---GGRGGGRGGMGSAGER 274
S G YG + GG G G +R +RG G GG DRGG GG GG RGG G G+R
Sbjct: 448 SGGGYGGDRGG--GYGGDRGGGYGGDRGGGYGG-DRGGYGGDRGGGYGGDRGGYG--GDR 502
Query: 275 GGFNKPGG 282
GG+ G
Sbjct: 503 GGYGGDRG 510
Score = 40.8 bits (94), Expect = 0.004
Identities = 32/74 (43%), Positives = 35/74 (47%), Gaps = 7/74 (9%)
Query: 220 GVYGQESGGFSGP----GENRSMSGPDNRGRGRGGFDRGGMSR--GGRGGGRGGMGSAGE 273
G YG + GG+ G G +R G D R RG G DRGG S G R GG GG S G
Sbjct: 496 GGYGGDRGGYGGDRGGYGGDRGGYGGD-RSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGG 554
Query: 274 RGGFNKPGGPMDEG 287
GG G D G
Sbjct: 555 YGGDRGGGYGGDRG 568
>gi|21327701 TBP-associated factor 15 isoform 1 [Homo sapiens]
Length = 592
Score = 355 bits (912), Expect = 5e-98
Identities = 242/573 (42%), Positives = 299/573 (52%), Gaps = 111/573 (19%)
Query: 38 QQSYGTYGQPTDVSYTQA-QTTATYGQTAYATSYGQPPTGYTTPTAPQAYSQPVQGYGT- 95
QQSY TYG P Y QA Q+ + YGQT +SYGQ +GY++ Y Q GY
Sbjct: 14 QQSYSTYGNPGSQGYGQASQSYSGYGQTT-DSSYGQNYSGYSS------YGQSQSGYSQS 66
Query: 96 -GAYDTTTATVTTTQASYAAQSAYGTQPAYPAYGQQPAATAPTSYSSTQPTSYDQSSYSQ 154
G Y+ QS+Y QP Y GQQ + S P SYDQ Y Q
Sbjct: 67 YGGYENQK------------QSSYSQQP-YNNQGQQQNMESSGSQGGRAP-SYDQPDYGQ 112
Query: 155 QNTYGQPSSYGQ-QSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQ 213
Q++Y Q S Y Q Q SY +QS+Y QQ SYSQ Y Q +Y + Q
Sbjct: 113 QDSYDQQSGYDQHQGSYDEQSNYDQQHD--------SYSQNQQSYHSQRENYSHHT---Q 161
Query: 214 DHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGE 273
D + YG+++ G+ G S G GRGRGG+D+ G RG G GG +
Sbjct: 162 DDRRDVSRYGEDNRGYGG-----SQGG----GRGRGGYDKDG--RGPMTGSSGG-----D 205
Query: 274 RGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKM 333
RGGF GG D GP D D +SDN+ I+VQGL + V+ D + +FFKQ G++K
Sbjct: 206 RGGFKNFGGHRDYGPRTDADSESD---NSDNNTIFVQGLGEGVSTDQVGEFFKQIGIIKT 262
Query: 334 NKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKP 393
NK+TG+PMI++Y DK+TGKPKG+ATVS++DPP+AKAA++WFDGK+F G+ +KVS A ++P
Sbjct: 263 NKKTGKPMINLYTDKDTGKPKGEATVSFDDPPSAKAAIDWFDGKEFHGNIIKVSFATRRP 322
Query: 394 PMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNP 453
MRGG G GG GR G RG RGGF RG G+P
Sbjct: 323 EF--MRGG--------------------GSGGGRRGRGGYRG--RGGFQGRG-----GDP 353
Query: 454 SGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPP-------PFPPPGGD 506
++GDW CPNP CGN NFA R CNQC P+PE P + G
Sbjct: 354 --------KSGDWVCPNPSCGNMNFARRNSCNQCNEPRPEDSRPSGGDFRGRGYGGERGY 405
Query: 507 RGRGGPGGMRGGRGGLMDRGGPGG--MFRGGRGGDRGGFRGGRGMDR--GGFGGGRRGGP 562
RGRGG GG RGG GG GG GG GG GDR G GG G DR GG+GG R GG
Sbjct: 406 RGRGGRGGDRGGYGGDRSGGGYGGDRSSGGGYSGDRSG--GGYGGDRSGGGYGGDRGGGY 463
Query: 563 GGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQER 595
GG G GG G RGG D+G + +R
Sbjct: 464 GGDRG------GGYGGDRGGGYGGDRGGYGGDR 490
Score = 81.3 bits (199), Expect = 2e-15
Identities = 75/201 (37%), Positives = 82/201 (40%), Gaps = 61/201 (30%)
Query: 400 GGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNV 459
GG G G GG GG G GG G GG GGDRGG G RG G GG
Sbjct: 453 GGYGGDRGGGYGGDRGGGYGGDRG-GGYGGDRGGYGGDRGG-GYGGDRGGYGGDRGG--- 507
Query: 460 QHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGR 519
GD G G + GGDR RGG GG RGG
Sbjct: 508 --YGGD----RGGYGGDRGGY-----------------------GGDRSRGGYGGDRGGG 538
Query: 520 GGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGG 579
G GG GG GGDR G GG G DRGG GG RGG GG +MGGR
Sbjct: 539 SGY------GGDRSGGYGGDRSG--GGYGGDRGGGYGGDRGGYGG-------KMGGR--- 580
Query: 580 RGGPGKMDKGEHRQERRDRPY 600
++R ++R+RPY
Sbjct: 581 ---------NDYRNDQRNRPY 592
Score = 54.7 bits (130), Expect = 2e-07
Identities = 55/164 (33%), Positives = 62/164 (37%), Gaps = 55/164 (33%)
Query: 399 RGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGN 458
RGG G G RGG GG G G G GG GGDRGG+ RG G GGG+
Sbjct: 483 RGGYGGDRGGGYGGD-RGGYGGDRGGYG--GDRGGYGGDRGGYGGDRSRGGYGGDRGGGS 539
Query: 459 VQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGG 518
G+ GGDR GG GG R G
Sbjct: 540 -----------------------------------GY--------GGDRS-GGYGGDRSG 555
Query: 519 RGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGP 562
GG GG GG GGDRGG+ GG+ R + +R P
Sbjct: 556 -------GGYGGDRGGGYGGDRGGY-GGKMGGRNDYRNDQRNRP 591
Score = 49.3 bits (116), Expect = 1e-05
Identities = 38/105 (36%), Positives = 44/105 (41%), Gaps = 5/105 (4%)
Query: 171 GQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYG-QQSSFRQDHPSSMGVYGQESGGF 229
G + YG Y G Y Y YG + + D S G YG + GG
Sbjct: 481 GDRGGYGGDRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDR--SRGGYGGDRGGG 538
Query: 230 SGPGENRSMS-GPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGE 273
SG G +RS G D G G GG DRGG G RGG G MG +
Sbjct: 539 SGYGGDRSGGYGGDRSGGGYGG-DRGGGYGGDRGGYGGKMGGRND 582
Score = 47.8 bits (112), Expect = 3e-05
Identities = 39/116 (33%), Positives = 44/116 (37%), Gaps = 10/116 (8%)
Query: 176 YGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGE 234
YG Y G Y Y YG R + G YG + GG+ G
Sbjct: 471 YGGDRGGGYGGDRGGYGGDRGGGYGGDRGGYGGD---RGGYGGDRGGYGGDRGGYGGDRS 527
Query: 235 NRSMSGPDNRGRGRGGFDRGG----MSRGGRGGGRGGMGSAGERGGF-NKPGGPMD 285
G G G GG GG S GG GG RGG G G+RGG+ K GG D
Sbjct: 528 RGGYGGDRGGGSGYGGDRSGGYGGDRSGGGYGGDRGG-GYGGDRGGYGGKMGGRND 582
Score = 45.8 bits (107), Expect = 1e-04
Identities = 35/70 (50%), Positives = 39/70 (55%), Gaps = 11/70 (15%)
Query: 220 GVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMS--RGGRGGGRGGMGSAGERGGF 277
G YG + GG G G +R G D RG G GG DRGG RGG GG RGG G G+RGG+
Sbjct: 469 GGYGGDRGG--GYGGDRGGYGGD-RGGGYGG-DRGGYGGDRGGYGGDRGGYG--GDRGGY 522
Query: 278 NKPGGPMDEG 287
GG G
Sbjct: 523 ---GGDRSRG 529
Score = 44.3 bits (103), Expect = 3e-04
Identities = 38/88 (43%), Positives = 42/88 (47%), Gaps = 11/88 (12%)
Query: 198 YSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGM- 256
Y SS G S R S G G SGG G G +R +RG G GG DRGG
Sbjct: 427 YGGDRSSGGGYSGDR----SGGGYGGDRSGG--GYGGDRGGGYGGDRGGGYGG-DRGGGY 479
Query: 257 --SRGGRGGGRGGMGSAGERGGFNKPGG 282
RGG GG RGG G G+RGG+ G
Sbjct: 480 GGDRGGYGGDRGG-GYGGDRGGYGGDRG 506
Score = 43.5 bits (101), Expect = 6e-04
Identities = 31/74 (41%), Positives = 37/74 (50%), Gaps = 8/74 (10%)
Query: 220 GVYGQESGGFSGPGENRSMSGPDNRGRG--RGGF--DRGGMS--RGGRGGGRGGMGSAGE 273
G YG + GG+ G + G D G G RGG+ DRGG RGG GG R G G+
Sbjct: 477 GGYGGDRGGYGG--DRGGGYGGDRGGYGGDRGGYGGDRGGYGGDRGGYGGDRSRGGYGGD 534
Query: 274 RGGFNKPGGPMDEG 287
RGG + GG G
Sbjct: 535 RGGGSGYGGDRSGG 548
Score = 42.7 bits (99), Expect = 0.001
Identities = 31/71 (43%), Positives = 35/71 (49%), Gaps = 8/71 (11%)
Query: 218 SMGVYGQE---SGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRG---GMGSA 271
S G YG + GG+SG G D G G GG DRGG G RGGG G G G
Sbjct: 423 SGGGYGGDRSSGGGYSGDRSGGGYGG-DRSGGGYGG-DRGGGYGGDRGGGYGGDRGGGYG 480
Query: 272 GERGGFNKPGG 282
G+RGG+ G
Sbjct: 481 GDRGGYGGDRG 491
Score = 42.4 bits (98), Expect = 0.001
Identities = 31/68 (45%), Positives = 36/68 (52%), Gaps = 8/68 (11%)
Query: 218 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSR---GGRGGGRGGMGSAGER 274
S G YG + GG G G +R +RG G GG DRGG GG GG RGG G G+R
Sbjct: 451 SGGGYGGDRGG--GYGGDRGGGYGGDRGGGYGG-DRGGYGGDRGGGYGGDRGGYG--GDR 505
Query: 275 GGFNKPGG 282
GG+ G
Sbjct: 506 GGYGGDRG 513
Score = 40.8 bits (94), Expect = 0.004
Identities = 32/74 (43%), Positives = 35/74 (47%), Gaps = 7/74 (9%)
Query: 220 GVYGQESGGFSGP----GENRSMSGPDNRGRGRGGFDRGGMSR--GGRGGGRGGMGSAGE 273
G YG + GG+ G G +R G D R RG G DRGG S G R GG GG S G
Sbjct: 499 GGYGGDRGGYGGDRGGYGGDRGGYGGD-RSRGGYGGDRGGGSGYGGDRSGGYGGDRSGGG 557
Query: 274 RGGFNKPGGPMDEG 287
GG G D G
Sbjct: 558 YGGDRGGGYGGDRG 571
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 105 bits (262), Expect = 1e-22
Identities = 142/492 (28%), Positives = 171/492 (34%), Gaps = 118/492 (23%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPS---QYSQQSSSYGQQSSFRQDH 215
G P + G + + G + S GQ P PP T + +P + S + ++
Sbjct: 312 GLPGAAGARGNDGARGSDGQPGPPG-PPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGE 370
Query: 216 PSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERG 275
P G G + G PG N S G G G M G G G G+ G RG
Sbjct: 371 PGPQGHAGAQ-GPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRG 429
Query: 276 GFNKPG--------GPMDEGPDLDL-GPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFK 326
G +PG GP E + + G P ED + + G N
Sbjct: 430 GAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGAN------------- 476
Query: 327 QCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKV 386
G+ G P P G + E P +
Sbjct: 477 --GLPGAAGERGAPGFR--------GPAGPNGIPGEKGPAGE------------------ 508
Query: 387 SLARKKPPMNSMRG--GLPPREGRGMPPPLRGGPGGPGGPG-----GPMGRMG--GRGGD 437
R P RG G P R+G P +RG PG PGGPG GP G G GR G
Sbjct: 509 ---RGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGP 565
Query: 438 RGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGC-GNQNFAWRTECNQCKAPKPEGFL 496
G PRG G G P GN + + PG G Q P G
Sbjct: 566 PGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQG-----------PPGKNGET 614
Query: 497 PPPFPP----PGGDRGRGGPGGMRG-----GRGGLMDR----------------GGPGGM 531
P PP PGGD+G GP G +G G GG G PGG
Sbjct: 615 GPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGK 674
Query: 532 FRGGRGGDRG--------GFRGGRGMDRGGFGGGRRGGPGGPPG----PLMEQMGGRRGG 579
G G+RG G RGG G G GG GP GPPG P ++ M G RGG
Sbjct: 675 GDAGAPGERGPPGLAGAPGLRGGAG-PPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGG 733
Query: 580 RGGPG-KMDKGE 590
G PG K DKGE
Sbjct: 734 LGSPGPKGDKGE 745
Score = 103 bits (257), Expect = 5e-22
Identities = 133/435 (30%), Positives = 162/435 (37%), Gaps = 71/435 (16%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G P G G G + P + G P S G S + P S
Sbjct: 498 GIPGEKGPAGERGAPGPAGPRGAAGEPGRDG-VPGGPGMRGMPGSPGGPGSDGKPGPPGS 556
Query: 219 MGVYGQESGGFSGPGENRSMSGPDNRGR-GRGGFD--RGGMSRGGRGGGRGGMGSAGERG 275
G ESG PG SGP RG+ G GF +G G+ G RGG G G +G
Sbjct: 557 QG----ESGRPGPPGP----SGP--RGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQG 606
Query: 276 GFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNK 335
K G +GP GP D + +QGL + G N
Sbjct: 607 PPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGT------------GGPPGENG 654
Query: 336 RTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPM 395
+ G+P PKGDA P A GK G+ + PP
Sbjct: 655 KPGEP-----------GPKGDA-----GAPGAPG------GKGDAGAP-----GERGPP- 686
Query: 396 NSMRGGLPPREGRGMPPPLRG-GPGGPGGPGGPMGRMG--GRGGDRGGFPPRGPRGSRGN 452
+ G R G G P P G G GP GP G G G G G+RGG GP+G +G
Sbjct: 687 -GLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGE 745
Query: 453 PSGGG--NVQHRAGDWQCPNPGCGNQNFAWRT-ECNQCKAPKPEGFLPPPFPPPGGDRGR 509
P G G V + G + P G A + + + AP G P P G+RG
Sbjct: 746 PGGPGADGVPGKDGP-RGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSP--GERGE 802
Query: 510 GGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPL 569
GP G G G G PGG G G++G GG G GG GP GPPGP
Sbjct: 803 TGPPGPAGFPGAPGQNGEPGGKGERGAPGEKG--EGGPPGVAGPPGG---SGPAGPPGP- 856
Query: 570 MEQMGGRRGGRGGPG 584
+ + G RG GGPG
Sbjct: 857 -QGVKGERGSPGGPG 870
Score = 88.6 bits (218), Expect = 2e-17
Identities = 139/514 (27%), Positives = 166/514 (32%), Gaps = 84/514 (16%)
Query: 122 PAYPAYGQQPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPP 181
P P P + P + PT Q+ Q ++Y S G G P
Sbjct: 123 PGIPGQPGSPGSPGPPGICESCPTG-PQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGP 181
Query: 182 TSYPPQTGSYSQAPSQ--YSQQSSSYGQQS-SFRQDHPSSMGVYGQ-----ESGGFSGPG 233
PP T + +P Y GQ S P ++G G ESG PG
Sbjct: 182 PG-PPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPG 240
Query: 234 ENRSMSGPDNRGRGRGGFDRGGMSRGGRG--GGRGGMGSAGERGGFNKPGGPMDEGPDLD 291
E R + GP +G G +G RG G G G G G + G P + G
Sbjct: 241 E-RGLPGPPGI-KGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGP 298
Query: 292 LGPPVDPDEDSDNSAIYVQGL--NDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKE 349
+GP P E G ND D GQP
Sbjct: 299 MGPRGAPGERGRPGLPGAAGARGNDGARGSD-----------------GQP--------- 332
Query: 350 TGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSK-------LKVSLARKKPPMNSMRGGL 402
G P T + P AK V G+ + + PP G
Sbjct: 333 -GPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGS 391
Query: 403 PPREGRGMPPPLRGGPG-----GPGGPGGPMGRMG--------GRGGDRGGFPPRGPRGS 449
P +G P + G PG GP GP G G G G+ G +G PRG RG
Sbjct: 392 PGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGE 451
Query: 450 RGNPSGGGNVQHRAGDWQCPNPGC-GNQNFAWRTECNQCKAPK-PEGFLPPPFPPPGGDR 507
G P G D PG G A + P P G P P G+R
Sbjct: 452 AGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGI--PGEKGPAGER 509
Query: 508 GRGGPGGMRGGRGGLMDRGGPGGM-FRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPP 566
G GP G RG G G PGG RG G G G+ G G R GP GP
Sbjct: 510 GAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPS 569
Query: 567 GPLMEQ--MG--------------GRRGGRGGPG 584
GP + MG G RGG GGPG
Sbjct: 570 GPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPG 603
Score = 85.5 bits (210), Expect = 1e-16
Identities = 131/464 (28%), Positives = 161/464 (34%), Gaps = 67/464 (14%)
Query: 159 GQPSSYGQQSS------YGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFR 212
GQP G+ + G + S G++ T PP + AP Q + + +
Sbjct: 774 GQPGDKGEGGAPGLPGIAGPRGSPGERGETG-PPGPAGFPGAPGQNGEPGGKGERGAPGE 832
Query: 213 QDHPSSMGVYGQESG-GFSGP-------GENRSMSGPDNRG----RGRGG--FDRGGMSR 258
+ GV G G G +GP GE S GP G RG G G
Sbjct: 833 KGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGP 892
Query: 259 GGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTL 318
G G G G G G PG P GP D G P E A G + +
Sbjct: 893 PGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAG---QPGEKGSPGAQGPPGAPGPLGI 949
Query: 319 DDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAK-----AAVEW 373
+ G M G P + E+GKP + PP + A
Sbjct: 950 AGITGARGLAGPPGMPGPRGSPGPQ-GVKGESGKPGANGLSGERGPPGPQGLPGLAGTAG 1008
Query: 374 FDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG--GPMGRM 431
G+D G+ L P + GG R G P G PG PG PG GP+G
Sbjct: 1009 EPGRD--GNPGSDGL----PGRDGSPGGKGDRGENGSP----GAPGAPGHPGPPGPVGP- 1057
Query: 432 GGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPK 491
G+ GDRG P GP G+ G AG P P + E
Sbjct: 1058 AGKSGDRGESGPAGPAGAPGP----------AGSRGAPGPQGPRGDKGETGERGAAGIKG 1107
Query: 492 PEGFL----PPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRG 545
GF P P P G +G G G G RG + G PG G G G G RG
Sbjct: 1108 HRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRG 1167
Query: 546 GRGMDRGGFGG----GRRGGPG--GPPGPLMEQMGGRR-GGRGG 582
RG +RG G G+ G PG G PGP +G G GG
Sbjct: 1168 NRG-ERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGG 1210
Score = 83.6 bits (205), Expect = 5e-16
Identities = 127/467 (27%), Positives = 142/467 (30%), Gaps = 90/467 (19%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G P G G+ G PT G Q Q G P
Sbjct: 600 GGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPG-ENGKPGE 658
Query: 219 MGVYGQESGGFSGPGENRSMSGPDNRG----RGRGGFDRGGMSRGGRGGGRGGMGSAGER 274
G G ++G PG P RG G G RGG G GG+G G G
Sbjct: 659 PGPKG-DAGAPGAPGGKGDAGAPGERGPPGLAGAPGL-RGGAGPPGPEGGKGAAGPPGPP 716
Query: 275 GGFNKPG---------GPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFF 325
G PG G GP D G P P D +G + A
Sbjct: 717 GAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAG-- 774
Query: 326 KQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLK 385
Q G G P I P+G E P A F G Q +
Sbjct: 775 -QPGDKGEGGAPGLPGI--------AGPRGSPGERGETGPPGPAG---FPGAPGQNGE-- 820
Query: 386 VSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGG--PGGPGGPMGRMGGRGGDRG---- 439
P G P +G G PP + G PGG P GP GP G G RG G
Sbjct: 821 --------PGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAA 872
Query: 440 GFPPR----GPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGF 495
GFP GP GS GNP G P+ G P P G
Sbjct: 873 GFPGARGLPGPPGSNGNPGPPG-----------PSGSPGKDG-----------PPGPAGN 910
Query: 496 LPPPFPPP-GGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGM 549
P P G +G G G +G G G PG + G G RG G G RG
Sbjct: 911 TGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGS 970
Query: 550 DRGGFGGGRRGGPG--------GPPGPL----MEQMGGRRGGRGGPG 584
G G PG GPPGP + G G G PG
Sbjct: 971 PGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPG 1017
Score = 77.4 bits (189), Expect = 3e-14
Identities = 121/444 (27%), Positives = 143/444 (32%), Gaps = 102/444 (22%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G P G GQ S G P P S P YS Q SY +S
Sbjct: 115 GIPGRNGDPGIPGQPGSPGSPGP---PGICESCPTGPQNYSPQYDSYDVKS--------- 162
Query: 219 MGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFN 278
GV G+ GP GP G G G GS G +G
Sbjct: 163 -GVAVGGLAGYPGPAGPPGPPGPP-----------------GTSGHPGSPGSPGYQG--- 201
Query: 279 KPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTG 338
PG P GP GPP G + + G
Sbjct: 202 PPGEPGQAGPSGPPGPP---------------------------------GAIGPSGPAG 228
Query: 339 QPMIHIYLDKETGKPKGDATVSYEDPPTAK--AAVEWFDG----KDFQGSKLKVSLARKK 392
+ D E+G+P PP K A + F G + F G +
Sbjct: 229 K-------DGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKG--ETG 279
Query: 393 PPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGD--RGGFPPRGPRGSR 450
P GLP G P RG PG G PG P G G RG D RG GP G
Sbjct: 280 APGLKGENGLPGENGAPGPMGPRGAPGERGRPGLP-GAAGARGNDGARGSDGQPGPPGPP 338
Query: 451 GNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLP---PPFPP----- 502
G G+ + +PG Q P P+G PP PP
Sbjct: 339 GTAGFPGSPGAKGEVGPAGSPGSNGAP-------GQRGEPGPQGHAGAQGPPGPPGINGS 391
Query: 503 PGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGF-RGGRGMDRGGFG-GGRRG 560
PGG +G GP G+ G G + RG PG G G RGG G+ +G G G RG
Sbjct: 392 PGG-KGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERG 450
Query: 561 GPGGPPGPLMEQMGGRRGGRGGPG 584
G P P + G+ G G PG
Sbjct: 451 EAGIPGVPGAKGEDGKDGSPGEPG 474
Score = 65.9 bits (159), Expect = 1e-10
Identities = 65/221 (29%), Positives = 80/221 (36%), Gaps = 65/221 (29%)
Query: 393 PPMNSMRGGLPPREGRGMPP--PLRGGPGGPGGPGGPMGRMG-----------GRGGDRG 439
PP S G P G PP P + GP GP GP G +G G GR G+RG
Sbjct: 184 PPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERG 243
Query: 440 GFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPP 499
P G +G G P G HR D +
Sbjct: 244 LPGPPGIKGPAGIPGFPGMKGHRGFDGR-------------------------------- 271
Query: 500 FPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGMDRGGF 554
G++G G G++G G + G PG M G G+RG G G RG D G
Sbjct: 272 ----NGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGND-GAR 326
Query: 555 GGGRRGGPGGPPGPL--------MEQMG--GRRGGRGGPGK 585
G + GP GPPG ++G G G G PG+
Sbjct: 327 GSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQ 367
Score = 63.2 bits (152), Expect = 7e-10
Identities = 81/298 (27%), Positives = 102/298 (34%), Gaps = 83/298 (27%)
Query: 353 PKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPP 412
P G+ PPTA +G+ QG K PP G+P R G P
Sbjct: 80 PFGECCAVCPQPPTAPTRPP--NGQGPQGPK-----GDPGPP------GIPGRNG---DP 123
Query: 413 PLRGGPGGPGGPGGP---------------------------MGRMGGRGGDRGGFPPRG 445
+ G PG PG PG P +G + G G G P G
Sbjct: 124 GIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPG 183
Query: 446 PRGSRGNPSGGGNVQH--------RAGDWQCPNP--GCGNQNFAWRT-ECNQCKAPKPEG 494
P G+ G+P G+ + +AG P P G A + E + P G
Sbjct: 184 PPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERG 243
Query: 495 FLPPP-------------------FPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGG 535
PP F G++G G G++G G + G PG M G
Sbjct: 244 LPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRG 303
Query: 536 RGGDRG-----GFRGGRGMDRGGFGGGRRGGPGGPPG----PLMEQMGGRRGGRGGPG 584
G+RG G G RG D G G + GP GPPG P G G G PG
Sbjct: 304 APGERGRPGLPGAAGARGND-GARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPG 360
Score = 61.6 bits (148), Expect = 2e-09
Identities = 69/218 (31%), Positives = 85/218 (38%), Gaps = 59/218 (27%)
Query: 412 PPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNP 471
PP GP GP G GP G + GR GD G P G GS G+P G + CP
Sbjct: 98 PPNGQGPQGPKGDPGPPG-IPGRNGDPG-IP--GQPGSPGSPGPPGICE------SCPT- 146
Query: 472 GCGNQNFAWRTECNQCKA----------PKPEGFLPPPFPP----------------PGG 505
G QN++ + + K+ P P G PP PP P G
Sbjct: 147 --GPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPG 204
Query: 506 DRGRGGPGGMRGGRGGLMDRGGPGGMF----RGGRGGDRG-----GFRGGRGMDRGGFGG 556
+ G+ GP G G G + GP G R GR G+RG G +G G+ GF G
Sbjct: 205 EPGQAGPSGPPGPPGAI-GPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIP--GFPG 261
Query: 557 --------GRRGGPGGPPGPLMEQMGGRRGGRGGPGKM 586
GR G G P ++ G G G PG M
Sbjct: 262 MKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPM 299
Score = 40.0 bits (92), Expect = 0.006
Identities = 40/135 (29%), Positives = 45/135 (33%), Gaps = 28/135 (20%)
Query: 468 CPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGG 527
CPNP + C C P PP P G +G GP G+ G G D G
Sbjct: 74 CPNP-----EIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNG---DPGI 125
Query: 528 PGGMFRGGRGGDRG-----------------GFRGGRGMDRGGFGG-GRRGGPGGPPGPL 569
PG G G G + G+ GG G GP GPPGP
Sbjct: 126 PGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGP- 184
Query: 570 MEQMGGRRGGRGGPG 584
G G G PG
Sbjct: 185 -PGTSGHPGSPGSPG 198
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 93.2 bits (230), Expect = 6e-19
Identities = 128/451 (28%), Positives = 163/451 (36%), Gaps = 74/451 (16%)
Query: 149 QSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQ--APSQYSQQSSSYG 206
Q + T G P G + G + G P + GS + AP Q + G
Sbjct: 250 QGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLP-G 308
Query: 207 QQSSFRQDHPSSMGVYGQESG-GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGR 265
++ R P G G + G +GP +GP GF G + G G +
Sbjct: 309 ERG--RPGAPGPAGARGNDGATGAAGPPGPTGPAGPP-------GFP-GAVGAKGEAGPQ 358
Query: 266 GGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFF 325
G GS G +G +PG P GP GP +P D A +G N + + F
Sbjct: 359 GPRGSEGPQGVRGEPGPP---GPAGAAGPAGNPGADGQPGA---KGANGAPGIAGAPGFP 412
Query: 326 KQCGVVKMNKRTGQPMIHIYLDKETGKP--KGDATVSYEDPPTAKAAVEWFDGKDFQGSK 383
G G P E G P KGD E P G++ +
Sbjct: 413 GARGPSGPQGPGGPPGPKGN-SGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRG- 470
Query: 384 LKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG--GDRGGF 441
AR +P + G PP RGGPG G PG G G +G G+RG
Sbjct: 471 -----ARGEPGPTGLPG----------PPGERGGPGSRGFPGAD-GVAGPKGPAGERGSP 514
Query: 442 PPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFP 501
P GP+GS G G +PG +P P+G PP
Sbjct: 515 GPAGPKGSPGEAGRPGEAGLPGAKGLTGSPG----------------SPGPDGKTGPP-- 556
Query: 502 PPGGDRGRGGPGGMRGGRG--GLMDRGGP-GGMFRGGRGGDRG-----GFRGGRGMDRGG 553
P G GR GP G G RG G+M GP G G+ G+RG G G G D
Sbjct: 557 GPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKD--- 613
Query: 554 FGGGRRGGPGGPPGPLMEQMGGRRGGRGGPG 584
G GP GP GP E+ G +G G PG
Sbjct: 614 -GEAGAQGPPGPAGPAGER--GEQGPAGSPG 641
Score = 88.2 bits (217), Expect = 2e-17
Identities = 124/452 (27%), Positives = 154/452 (34%), Gaps = 71/452 (15%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G P G + G G Q P G+ + AP + + + Q P
Sbjct: 668 GAPGPSGARGERGFPGERGVQGPPGPAGPRGA-NGAPGNDGAKGDAGAPGAPGSQGAPGL 726
Query: 219 MGVYGQE-SGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGF 277
G+ G+ + G GP +R +GP +G G+ G RG G G G
Sbjct: 727 QGMPGERGAAGLPGPKGDRGDAGP-----------KGADGSPGKDGVRGLTGPIGPPGPA 775
Query: 278 NKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRT 337
PG + GP GP D G G
Sbjct: 776 GAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPG---------------PAGFAGPPGAD 820
Query: 338 GQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGK--DFQGSKLKVSLARKKPPM 395
GQP G+P GDA + P A G + K + PP
Sbjct: 821 GQP-------GAKGEP-GDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPG 872
Query: 396 NSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG-----------GDRGGFPPR 444
+ G P GR + PP G GP GP GP G+ GG+G G+ G P
Sbjct: 873 AT---GFPGAAGR-VGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPP 928
Query: 445 GPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPE-GFLPPPFPPP 503
GP G +G+P G AG P P Q A + + E GF P P P
Sbjct: 929 GPAGEKGSPGADGP----AGAPGTPGP----QGIAGQRGVVGLPGQRGERGF--PGLPGP 978
Query: 504 GGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRG- 560
G+ G+ GP G G RG G PG G G G G G G D G RG
Sbjct: 979 SGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGE 1038
Query: 561 -GPGGPPGPLMEQMGGRRGGRGGPGKM-DKGE 590
GP GPPG G G G GK D+GE
Sbjct: 1039 TGPAGPPG--APGAPGAPGPVGPAGKSGDRGE 1068
Score = 83.2 bits (204), Expect = 6e-16
Identities = 106/366 (28%), Positives = 123/366 (33%), Gaps = 70/366 (19%)
Query: 260 GRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLD 319
G G RG G AG G PG P GP GPP P + + G ++ T
Sbjct: 115 GDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGG 174
Query: 320 -DLADFFKQCGVVKMNKRTGQPMIHIYLDK--ETGKPKGDATVSYEDPPTAKAAVEWFDG 376
+ G + G P + E G+P + PP +G
Sbjct: 175 ISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGK----NG 230
Query: 377 KDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMP-----PPLRG--------GPGGPGG 423
D + K P RG P+ RG+P P ++G G G G
Sbjct: 231 DDGEAGK---------PGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAG 281
Query: 424 PGGPMGRMG--GRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWR 481
P GP G G G G G PRG G RG P G R D G
Sbjct: 282 PAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAG--------- 332
Query: 482 TECNQCKAPKPEGFLPPP-FPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDR 540
P P G PP FP G +G GP G RG G RG PG G G
Sbjct: 333 -------PPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPA 385
Query: 541 G--------GFRGGRG----MDRGGFGGGR----RGGPGGPPGPLMEQMGGRRGGRGGPG 584
G G +G G GF G R GPGGPPGP G G G PG
Sbjct: 386 GNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGP-----KGNSGEPGAPG 440
Query: 585 -KMDKG 589
K D G
Sbjct: 441 SKGDTG 446
Score = 82.8 bits (203), Expect = 8e-16
Identities = 137/499 (27%), Positives = 158/499 (31%), Gaps = 100/499 (20%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQ--APSQYSQQSSSYGQQSSFRQDHP 216
G P G G + G Q P P G+ + AP + Q P
Sbjct: 401 GAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPP 460
Query: 217 SSMGVYGQ-----ESGGFSGPGENRSMSGPDNRG----------RGRGGFDRGGMSRGGR 261
G G+ E G PG GP +RG +G G +RG G
Sbjct: 461 GPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAG-ERGSPGPAGP 519
Query: 262 GGGRGGMGSAGERG---GFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTL 318
G G G GE G G P GPD GPP +D G
Sbjct: 520 KGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARG---- 575
Query: 319 DDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKD 378
Q GV+ G G+P PP A
Sbjct: 576 --------QAGVMGFPGPKGA----------AGEPGKAGERGVPGPPGAVGPAGKDGEAG 617
Query: 379 FQGSKLKVSLARKK----PPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG-----GPMG 429
QG A ++ P + GLP G PP G PG G PG GP G
Sbjct: 618 AQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAG---PPGEAGKPGEQGVPGDLGAPGPSG 674
Query: 430 RMGGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPN-PGC----GNQNFAWRT 482
G RG G+RG P GP G RG GN GD P PG G Q
Sbjct: 675 ARGERGFPGERGVQGPPGPAGPRGANGAPGN-DGAKGDAGAPGAPGSQGAPGLQGMPGER 733
Query: 483 ECNQCKAPK-------PEGF-----------LPPPFPPPG--------GDRGRGGPGGMR 516
PK P+G L P PPG G+ G GP G
Sbjct: 734 GAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPT 793
Query: 517 GGRGGLMDRGGPG----GMFRGGRGGD-RGGFRG--GRGMDRGGFGGGRRGGPGGPPGPL 569
G RG DRG PG F G G D + G +G G +G G GP GPPGP+
Sbjct: 794 GARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPI 853
Query: 570 ----MEQMGGRRGGRGGPG 584
G RG G PG
Sbjct: 854 GNVGAPGAKGARGSAGPPG 872
Score = 82.0 bits (201), Expect = 1e-15
Identities = 142/525 (27%), Positives = 167/525 (31%), Gaps = 53/525 (10%)
Query: 74 PTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGTQPAYPAYGQQPAA 133
P G P P P TG T A P P P
Sbjct: 87 PEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGP 146
Query: 134 TAPTSYSSTQPTSYDQSSYS-QQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS 192
P Q SY + + G S G G + G PP + PQ +
Sbjct: 147 PGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPG--PPGAPGPQ--GFQ 202
Query: 193 QAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFD 252
P + + +S P G G E+G PGE R GP G
Sbjct: 203 GPPGEPGEPGASGPMGPRGPPGPPGKNGDDG-EAGKPGRPGE-RGPPGPQGARGLPGTAG 260
Query: 253 RGGMSRGGRG--GGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQ 310
GM +G RG G G G AG G +PG P + G +GP P E A
Sbjct: 261 LPGM-KGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPA 319
Query: 311 GL--NDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKP--KGDATVSYEDPPT 366
G ND T G TG G P G E P
Sbjct: 320 GARGNDGAT-----------GAAGPPGPTG----------PAGPPGFPGAVGAKGEAGPQ 358
Query: 367 AKAAVEWFDG-KDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPG--G 423
E G + G A P N G P +G P + G PG PG G
Sbjct: 359 GPRGSEGPQGVRGEPGPPGPAGAA--GPAGNPGADGQPGAKGANGAPGIAGAPGFPGARG 416
Query: 424 PGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTE 483
P GP G GG G +G G GS+G+ +G G P P R E
Sbjct: 417 PSGPQG-PGGPPGPKGNSGEPGAPGSKGD-TGAKGEPGPVGVQGPPGPAGEEGKRGARGE 474
Query: 484 CNQCKAPKPEGFLPPP----FPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGD 539
P P G P FP G G GP G RG G +G PG GR G+
Sbjct: 475 PGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPG---EAGRPGE 531
Query: 540 RGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPG 584
G G +G+ G G G GPPGP + GR G G PG
Sbjct: 532 -AGLPGAKGL-TGSPGSPGPDGKTGPPGPAGQD--GRPGPPGPPG 572
Score = 77.0 bits (188), Expect = 5e-14
Identities = 113/455 (24%), Positives = 150/455 (32%), Gaps = 78/455 (17%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQ----APSQYSQQSSSYGQQSSFRQD 214
G P G G+ G PT G + P+ ++ + GQ + +
Sbjct: 770 GPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGA--KG 827
Query: 215 HPSSMGVYGQE-----SGGFSGPGENRSMSGPDNRGR-------GRGGFDR-----GGMS 257
P G G +G PG ++ P +G G GF G
Sbjct: 828 EPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPG 887
Query: 258 RGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVT 317
G G G G AG+ GG G G ++GPP P + + G +
Sbjct: 888 PSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPG 947
Query: 318 LDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKP--KGDATVSYEDPPTAKAAVEWFD 375
Q GVV + + G+ L +G+P +G + S E P
Sbjct: 948 TPGPQGIAGQRGVVGLPGQRGERGFP-GLPGPSGEPGKQGPSGASGERGPPGPMGPPGLA 1006
Query: 376 GKDFQGSKLKVSLARKKPPMNSMRGGLPPR--EGRGMPPPLRGGPGGPG----------- 422
G + + A P + G R G PP G PG PG
Sbjct: 1007 GPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDR 1066
Query: 423 ------GPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQ 476
GP GP+G +G RG P GP+G RG+ G R G++
Sbjct: 1067 GETGPAGPAGPVGPVGARG-------PAGPQGPRGDKGETGEQGDRGIK--------GHR 1111
Query: 477 NFAWRTECNQCKAPKPEGFLPPPFPPPG-GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGG 535
F+ G PP PP G++G G G G RG G PG G
Sbjct: 1112 GFS--------------GLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNG 1157
Query: 536 RGGDRG--GFRGGRGMDRGGFGGGRRGGPGGPPGP 568
G G G RG G D G G GP GPPGP
Sbjct: 1158 LPGPIGPPGPRGRTG-DAGPVGPPGPPGPPGPPGP 1191
Score = 75.9 bits (185), Expect = 1e-13
Identities = 137/484 (28%), Positives = 168/484 (34%), Gaps = 88/484 (18%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQD--HP 216
G P + G Q + G Q G++ P G A + + S P
Sbjct: 713 GAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPP 772
Query: 217 SSMGVYGQES-GGFSGP-GENRSMSGPDNRGR----GRGGFDRGGMSRGGRGGGRGGMGS 270
G G + G SGP G + P +RG G GF G G+ G +G G
Sbjct: 773 GPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGF-AGPPGADGQPGAKGEPGD 831
Query: 271 AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGV 330
AG +G D GP GP P + A +G S F G
Sbjct: 832 AGAKG---------DAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGR 882
Query: 331 VKM---NKRTGQPMIHIYLDKETGK-PKGDA-------TVSYEDPPTAKAAVEWFDGKDF 379
V + G P KE GK P+G+ V PP A + G D
Sbjct: 883 VGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPP-GPAGEKGSPGADG 941
Query: 380 QGSKLKVSLARKKPPMNSMRG-----GLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG-- 432
A P + G GLP + G RG PG PG P G G+ G
Sbjct: 942 PAG------APGTPGPQGIAGQRGVVGLPGQRGE------RGFPGLPG-PSGEPGKQGPS 988
Query: 433 GRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCP----NPGCGNQNFAWRTECNQCK 488
G G+RG P GP G G P G + G P +PG R E
Sbjct: 989 GASGERGPPGPMGPPGLAGPPGESGR-EGAPGAEGSPGRDGSPGAKGD----RGETGPAG 1043
Query: 489 APKPEGF--LPPPFPPPG--GDRGRGGPGGMRGGRGGLMDRG--GPGGMFRGGRG----- 537
P G P P P G GDRG GP G G G + RG GP G RG +G
Sbjct: 1044 PPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGP-RGDKGETGEQ 1102
Query: 538 GDRG--GFRGGRGM-----------DRGGFGG----GRRGGPGGPPGPLMEQMGGRRGGR 580
GDRG G RG G+ ++G G G RG PG P + + G G
Sbjct: 1103 GDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPI 1162
Query: 581 GGPG 584
G PG
Sbjct: 1163 GPPG 1166
Score = 70.5 bits (171), Expect = 4e-12
Identities = 72/197 (36%), Positives = 81/197 (41%), Gaps = 34/197 (17%)
Query: 417 GPGGPGGPGGPMGRMG--GRGGDRG--GFP-PRGPRGSRGNPSGGGNV---------QHR 462
GP G GP GP G G GR G G G P P GP G G P GGN +
Sbjct: 112 GPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKS 171
Query: 463 AGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGL 522
G P P + R AP P+GF PP P G+ G GP G RG G
Sbjct: 172 TGGISVPGPMGPS---GPRGLPGPPGAPGPQGFQGPPGEP--GEPGASGPMGPRGPPGPP 226
Query: 523 MDRGGPGGMFRGGRGGDRG--GFRGGRGM-DRGGFGG--GRRG--------GPGGPPGPL 569
G G + GR G+RG G +G RG+ G G G RG G GP GP
Sbjct: 227 GKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPK 286
Query: 570 MEQMGGRRGGRGGPGKM 586
E G G G PG+M
Sbjct: 287 GEP--GSPGENGAPGQM 301
Score = 44.3 bits (103), Expect = 3e-04
Identities = 77/326 (23%), Positives = 95/326 (29%), Gaps = 51/326 (15%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G P G G + G+ P P + G P ++ S + P
Sbjct: 893 GPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGP-PGPAGEKGSPGADGPAGAPGTPGP 951
Query: 219 MGVYGQ-----------ESG--GFSGPGENRSMSGPDNRGRGRGGFDRGG----MSRGGR 261
G+ GQ E G G GP GP RG G G
Sbjct: 952 QGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGE 1011
Query: 262 GGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDL 321
G G G+ G G PG D G GPP P + G +
Sbjct: 1012 SGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGP 1071
Query: 322 ADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDF-- 379
A G V G P+GD + E F G
Sbjct: 1072 AGPAGPVGPVGARGPAGPQ-----------GPRGDKGETGEQGDRGIKGHRGFSGLQGPP 1120
Query: 380 --------QGSKLKVSLARKKPPMNSMRGGLPPREG-RGMPPPLRGGPGGPGGPGGPMGR 430
QG A + P S G P ++G G+P P+ GP GP G G G
Sbjct: 1121 GPPGSPGEQGPSGASGPAGPRGPPGS--AGAPGKDGLNGLPGPI--GPPGPRGRTGDAGP 1176
Query: 431 MGGRGGDRGGFPPRGPRGSRGNPSGG 456
+G G P GP G G PS G
Sbjct: 1177 VGPPG-------PPGPPGPPGPPSAG 1195
Score = 32.0 bits (71), Expect = 1.7
Identities = 39/153 (25%), Positives = 48/153 (31%), Gaps = 11/153 (7%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFR--QDHP 216
G P G G + G P G+ A Q + + R + H
Sbjct: 1052 GAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHR 1111
Query: 217 SSMGVYGQE----SGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAG 272
G+ G S G GP +GP RG G G + G G G +G G
Sbjct: 1112 GFSGLQGPPGPPGSPGEQGPSGASGPAGP----RGPPG-SAGAPGKDGLNGLPGPIGPPG 1166
Query: 273 ERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNS 305
RG G GP GPP P D S
Sbjct: 1167 PRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFS 1199
>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
Length = 1499
Score = 90.9 bits (224), Expect = 3e-18
Identities = 133/476 (27%), Positives = 166/476 (34%), Gaps = 109/476 (22%)
Query: 125 PAYGQQPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY 184
P P + P Q ++ Q Q G P G+ G+ +G Q P
Sbjct: 437 PGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGP 496
Query: 185 PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR 244
P + G + P ++G G G G NR G D
Sbjct: 497 PGEEGKRGP-------------------RGDPGTVGPPGPV--GERGAPGNRGFPGSDGL 535
Query: 245 GRGRGGF-DRGGMSRGGRGGGRGGMGSAGERG---GFNKPGGPMDEGPDLDLGPPVDPDE 300
+G +RG + G G +G G GE G G P +GP+ LGP P E
Sbjct: 536 PGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGE 595
Query: 301 DS---DNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKP--KG 355
D +I ++G S+ G+ +G P GKP G
Sbjct: 596 DGRPGPPGSIGIRGQPGSM------------GLPGPKGSSGDP----------GKPGEAG 633
Query: 356 DATVSYEDPPTAKAAVEWFDGKDFQ-GSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPL 414
+A V P + A GKD + G V PP GL G PP
Sbjct: 634 NAGV-----PGQRGA----PGKDGEVGPSGPVG-----PP------GLAGERGEQGPPGP 673
Query: 415 RGGPG--GPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPN 470
G G GP GP G G+ G +G GD G P GPRG RGNP G
Sbjct: 674 TGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERG------------E 721
Query: 471 PGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGG 530
PG E P+G P P P G G GP G++G G G PG
Sbjct: 722 PGI----TGLPGEKGMAGGHGPDG--PKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGP 775
Query: 531 MFRGGRGGDRGGFRGGRGMDRGGFGGGRRG--GPGGPPGPLMEQMGGRRGGRGGPG 584
GDRGG G +G + G RG GP GPPGP G G +G PG
Sbjct: 776 K------GDRGGI-GEKGAEGTAGNDGARGLPGPLGPPGP-----AGPTGEKGEPG 819
Score = 90.9 bits (224), Expect = 3e-18
Identities = 143/493 (29%), Positives = 171/493 (34%), Gaps = 118/493 (23%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G P + G + G Q G+ P P + G R P S
Sbjct: 567 GLPGARGLTGNPGVQGPEGKLGPLGAPGEDG----------------------RPGPPGS 604
Query: 219 MGVYGQESGGFSGPGENRSMSGPDNRGR-GRGGF--DRGGMSRGGRGGGRGGMGS---AG 272
+G+ GQ G PG S P G G G RG + G G G +G AG
Sbjct: 605 IGIRGQP-GSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAG 663
Query: 273 ERGGFNKPGG------PMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFK 326
ERG PG P GP + G P D D A+ G
Sbjct: 664 ERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERG--- 720
Query: 327 QCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKV 386
+ G+ + G H D G P T PP QG +
Sbjct: 721 EPGITGLPGEKGMAGGH-GPDGPKGSPGPSGTPGDTGPP------------GLQGMPGER 767
Query: 387 SLARKKPPMNSMRGGLPPR--EG-------RGMPPPLRGGPGGPGGPGGPMGRMGGRGGD 437
+A P RGG+ + EG RG+P PL GP GP GP G G G RG
Sbjct: 768 GIAGTPGPKGD-RGGIGEKGAEGTAGNDGARGLPGPL--GPPGPAGPTGEKGEPGPRG-- 822
Query: 438 RGGFPPRGPRGSRGNP-SGGGNVQHRAGDWQCPNPGCGNQNFAWRT----ECNQCKAPKP 492
GP GSRGNP S G N A + P G + +P P
Sbjct: 823 -----LVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGP 877
Query: 493 EGFLPPPFP-----------------PPG-----GDRGRGGPGGMRGGRG-----GLMDR 525
+G P P PPG G GR GP G G G G +
Sbjct: 878 QGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGK 937
Query: 526 GGPGGMFRG-----GRGGDRG--GFRGGRGMDRGGFGGGRRGGPGGPPGPL-------ME 571
GP G+ RG GR GDRG G GG G D+G G + GP GPPGP +
Sbjct: 938 EGPPGL-RGDPGSHGRVGDRGPAGPPGGPG-DKGDPGEDGQPGPDGPPGPAGTTGQRGIV 995
Query: 572 QMGGRRGGRGGPG 584
M G+RG RG PG
Sbjct: 996 GMPGQRGERGMPG 1008
Score = 87.8 bits (216), Expect = 3e-17
Identities = 133/459 (28%), Positives = 166/459 (36%), Gaps = 79/459 (17%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G P S G+ G + G P P + G P Q ++G P
Sbjct: 315 GAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLG--PQGAPGQRGAHGMPGK-----PGP 367
Query: 219 MGVYG-QESGGFSGPGENRSMSGPDN-RG----RGRGGFDRGGMSRGGRGGGRGGMGSAG 272
MG G S GF G + +GP RG +G+ G + G G G G +G+ G
Sbjct: 368 MGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRG-ETGPPGPVGSPGLPGAIGTDG 426
Query: 273 ERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVK 332
G G P GP GPP P QG+ + F + G
Sbjct: 427 TPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGP---QGIRGQPGDPGVPGFKGEAGP-- 481
Query: 333 MNKRTGQPMIH-----IYLDKETGK--PKGD-ATVSYEDPPTAKAAV--EWFDGKDF--- 379
G+P H I E GK P+GD TV P + A F G D
Sbjct: 482 ----KGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPG 537
Query: 380 -QGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPG--GPGGPMGRMGGRGG 436
+G++ + P S G P R G P RG G PG GP G +G +G G
Sbjct: 538 PKGAQGERGPVGSSGPKGSQ--GDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGE 595
Query: 437 DRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPG-CGNQNFAWRTECNQCKAPKPEGF 495
D PP G G RG P G + PG GN Q AP +G
Sbjct: 596 DGRPGPP-GSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVP-----GQRGAPGKDGE 649
Query: 496 LPP--PFPPPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDR 551
+ P P PPG G+RG GP G G +G G PG GG+ GD+G
Sbjct: 650 VGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPG---EGGKPGDQGV--------- 697
Query: 552 GGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGE 590
G G GPL G RG RG PG ++GE
Sbjct: 698 --------PGDPGAVGPL-----GPRGERGNPG--ERGE 721
Score = 86.7 bits (213), Expect = 6e-17
Identities = 116/437 (26%), Positives = 149/437 (34%), Gaps = 51/437 (11%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G P S G + G + G + P + G Q + S+ + +
Sbjct: 135 GPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQ 194
Query: 219 MGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFN 278
M ++SG S G GP RG G+ GG G G GE G
Sbjct: 195 MAGLDEKSGLGSQVGLMPGSVGPVG--------PRGPQGLQGQQGGAGPTGPPGEPGDPG 246
Query: 279 KPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTG 338
G GP+ GPP P ED + G F G+ + G
Sbjct: 247 PMGPIGSRGPE---GPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRG 303
Query: 339 QPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSM 398
H L+ G+ + P A+ + G + + L + P
Sbjct: 304 ----HKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGR--LGPQGAPGQRG 357
Query: 399 RGGLPPREGRGMPPPLRGGPGGPGGPG-----GPMGRMGGRG--GDRGGFPPRGPRGSRG 451
G+P + G P + G G PG PG GP G G G G RG P GP GS G
Sbjct: 358 AHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPG 417
Query: 452 NPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGG 511
P G +PG P G PP P G +G G
Sbjct: 418 LPGAIGTDGTPGAKGPTGSPGTSG----------------PPGSAGPPGSP--GPQGSTG 459
Query: 512 PGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRGGPG--GPPG 567
P G+RG G D G PG G G+ G G +G G G RG PG GPPG
Sbjct: 460 PQGIRGQPG---DPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPG 516
Query: 568 PLMEQMGGRRGGRGGPG 584
P+ E+ G G RG PG
Sbjct: 517 PVGER--GAPGNRGFPG 531
Score = 81.3 bits (199), Expect = 2e-15
Identities = 124/447 (27%), Positives = 143/447 (31%), Gaps = 103/447 (23%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G P S G+ G G Q P P G + P Q S Q +
Sbjct: 831 GNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGE-PGQKGDAGSPGPQGLAGSPGPHGP 889
Query: 219 MGVYGQESG----------GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRG-GRGGGRGG 267
GV G + G GF G GP G G G G G
Sbjct: 890 NGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGS 949
Query: 268 MGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQ 327
G G+RG PGGP D+G D G P D G Q
Sbjct: 950 HGRVGDRGPAGPPGGPGDKG---DPGEDGQPGPDGPPGPAGTTG---------------Q 991
Query: 328 CGVVKMNKRTGQPMIHIYLDKETGKP--KGDATVSYEDPPTAKAAVEWFDGKDFQGSKLK 385
G+V M + G E G P G A + PT
Sbjct: 992 RGIVGMPGQRG----------ERGMPGLPGPAGTPGKVGPTG------------------ 1023
Query: 386 VSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG--GRGGDRGGFPP 443
+ K PP G + P G P GP GP G G GR G G GDRG P
Sbjct: 1024 -ATGDKGPP-----GPVGPPGSNG--PVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGP 1075
Query: 444 RGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPP 503
G GS+G P G V Q +PG P PP
Sbjct: 1076 AGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRG-----------------------PIGPP 1112
Query: 504 G--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRR 559
G G RG GP G RG +G DRG G G G +G G G G ++G G
Sbjct: 1113 GRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNG-EQGSAGIPGP 1171
Query: 560 GGPGGPPGPLMEQMGGRRGGRGGPGKM 586
GP GPPGP+ G G G PG +
Sbjct: 1172 FGPRGPPGPV-----GPSGKEGNPGPL 1193
Score = 80.1 bits (196), Expect = 5e-15
Identities = 144/503 (28%), Positives = 171/503 (33%), Gaps = 117/503 (23%)
Query: 155 QNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQD 214
Q G P + G G++ + G++ G A G +
Sbjct: 695 QGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAG----------GHGPDGPKG 744
Query: 215 HPSSMGVYGQESG-GFSG-PGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAG 272
P G G G G PGE P +G DRGG+ G G G G+ G
Sbjct: 745 SPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKG------DRGGIGEKGAEGTAGNDGARG 798
Query: 273 ERGGFNKPG--GPMDE----GPDLDLGPP---VDPDEDSDNSAIYVQGLNDSVTLDDLAD 323
G PG GP E GP +GPP +P +N G D
Sbjct: 799 LPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPD---- 854
Query: 324 FFKQCGVVKMNKRTGQPMIHIYLDKETGKP--KGDATVSYEDPPTAKAAVEWFDGKDFQG 381
GQP + E G+P KGDA P A G +
Sbjct: 855 --------------GQPGV----KGEPGEPGQKGDAG---SPGPQGLAGSPGPHGPNGVP 893
Query: 382 SKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG-----G 436
LK + PP + G P GR PP GP G GP GP+G G G G
Sbjct: 894 G-LKGGRGTQGPPGAT---GFPGSAGRVGPP----GPAGAPGPAGPLGEPGKEGPPGLRG 945
Query: 437 DRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNP-------GCGNQNF-----AWRTEC 484
D G G RG G P G G+ D Q P P G Q R E
Sbjct: 946 DPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQ-PGPDGPPGPAGTTGQRGIVGMPGQRGER 1004
Query: 485 NQCKAPKPEGFLPPPFPPPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG- 541
P P G P P G GD+G GP G G G + + G G G G G
Sbjct: 1005 GMPGLPGPAG-TPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGA 1063
Query: 542 -GFRGGRGMDRGGFG-------------------GGRRGGPG--GPPGPLMEQMGGRRGG 579
G RG RG D G G G+RG PG GP GP GR G
Sbjct: 1064 VGERGDRG-DPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGP-----PGRAGK 1117
Query: 580 RGGPG----KMDKGEHRQERRDR 598
RG PG + DKG+H +R DR
Sbjct: 1118 RGLPGPQGPRGDKGDH-GDRGDR 1139
Score = 75.5 bits (184), Expect = 1e-13
Identities = 146/571 (25%), Positives = 185/571 (32%), Gaps = 122/571 (21%)
Query: 121 QPAYPAYGQQPAATAPTSYS---STQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYG 177
QP P P+ P S S Q D+ S P S G G Q G
Sbjct: 169 QPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQG 228
Query: 178 QQP---PTSYPPQTGSY-------SQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESG 227
QQ PT P + G S+ P + G+ R +P +G G
Sbjct: 229 QQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPG--RNGNPGEVGFAGSPGA 286
Query: 228 -GFSGP----------------GENRSMSGPDNRGRGRGGFDRGGMS----RG--GRGGG 264
GF G G + P ++G G M RG G G
Sbjct: 287 RGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGR 346
Query: 265 RGGMGSAGERGGFNKPGGPMDEGP---------------DLDLGPPVDPDEDSDNSAIYV 309
G G+ G+RG PG P GP + GP +
Sbjct: 347 LGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGE 406
Query: 310 QGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKA 369
G V L G TG P T P G A P
Sbjct: 407 TGPPGPVGSPGLPGAIGTDGTPGAKGPTGSP--------GTSGPPGSAGPPGSPGPQGST 458
Query: 370 AVEWFDGKD-------FQGSKLKVSLARKKPPMNSMRG--GLPPREGRGMPPPLRGGPG- 419
+ G+ F+G + + +P + ++G G P EG+ P RG PG
Sbjct: 459 GPQGIRGQPGDPGVPGFKGE----AGPKGEPGPHGIQGPIGPPGEEGKRGP---RGDPGT 511
Query: 420 -GPGGPGGPMGRMGGRG--------------GDRGGFPPRGPRGSRGNPSGGGNVQHRAG 464
GP GP G G G RG G+RG GP+GS+G+P G
Sbjct: 512 VGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGA 571
Query: 465 DWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPG-GDRGRGGPGGMRGGRGGLM 523
NPG + AP +G P PP G RG+ G G+ G +G
Sbjct: 572 RGLTGNPGVQGPE----GKLGPLGAPGEDG---RPGPPGSIGIRGQPGSMGLPGPKGSSG 624
Query: 524 DRGGPGGMFRGGRGGDRG-----GFRGGRG-MDRGGFGG--GRRGGPG--------GPPG 567
D G PG G G RG G G G + G G G +G PG GPPG
Sbjct: 625 DPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPG 684
Query: 568 PLMEQMGGRRGGR---GGPGKMDKGEHRQER 595
P E GG+ G + G PG + R ER
Sbjct: 685 PPGE--GGKPGDQGVPGDPGAVGPLGPRGER 713
Score = 70.1 bits (170), Expect = 6e-12
Identities = 122/419 (29%), Positives = 152/419 (36%), Gaps = 85/419 (20%)
Query: 240 GPDNRGRGRGGFD---------RGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDL 290
G N GRGR G G R G G G G GERG +PG +G D
Sbjct: 103 GNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDG 162
Query: 291 DLGPPVD---PDEDSDNSAIYVQGLN-----DSVTLDDLADFFKQCGVVKMNKRTGQPMI 342
+ G P P S GL+ LD+ + Q G++ + P
Sbjct: 163 EPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRG 222
Query: 343 HIYLDKETG--------------KPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSL 388
L + G P G + P K + G++ G+ +V
Sbjct: 223 PQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRN--GNPGEVGF 280
Query: 389 ARKKPPMNSMRG--GLPPREG----RGMPPPLRGGPGGPG-----GPGGPMGRMG----- 432
A P G GLP +G +G+ P +G G PG GP GPMG MG
Sbjct: 281 A-GSPGARGFPGAPGLPGLKGHRGHKGLEGP-KGEVGAPGSKGEAGPTGPMGAMGPLGPR 338
Query: 433 GRGGDRGGFPPR---GPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKA 489
G G+RG P+ G RG+ G P G + G P N + E A
Sbjct: 339 GMPGERGRLGPQGAPGQRGAHGMPGKPGPM----GPLGIPGSSGFPGNPGMKGEAGPTGA 394
Query: 490 PKPEG--------FLPPPFPPPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGD 539
PEG P P PG G G G G +G G G PG G G
Sbjct: 395 RGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGP 454
Query: 540 RG-----GFRGGRGMDRG--GFGG--GRRGGPG-----GPPGPLMEQMGGRRGGRGGPG 584
+G G RG G D G GF G G +G PG GP GP E+ G+RG RG PG
Sbjct: 455 QGSTGPQGIRGQPG-DPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEE--GKRGPRGDPG 510
Score = 59.7 bits (143), Expect = 7e-09
Identities = 70/218 (32%), Positives = 84/218 (38%), Gaps = 24/218 (11%)
Query: 396 NSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNP 453
N RG + G+ P + G G PG P GP G G RG G +G PRGP+G G P
Sbjct: 106 NFGRGRKGQKGEPGLVPVVTGIRGRPG-PAGPPGSQGPRGERGPKGRPGPRGPQGIDGEP 164
Query: 454 S--GGGNVQHRAGDWQCPNP-GCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRG 510
G G P P G A ++ + L P P G RG
Sbjct: 165 GVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQ 224
Query: 511 GPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMD----------RGGFGG-- 556
G G +GG G G PG G G RG G G G D GF G
Sbjct: 225 GLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSP 284
Query: 557 GRRGGPGGPPGPLMEQMGGRRGGRGGPGKM----DKGE 590
G RG PG P P ++ G +G G G++ KGE
Sbjct: 285 GARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGE 322
Score = 59.3 bits (142), Expect = 1e-08
Identities = 69/237 (29%), Positives = 86/237 (36%), Gaps = 54/237 (22%)
Query: 399 RGGLPPREGRGMP--PPLRGGPGGPGGPGGP------------------MGRMGGRGGDR 438
+G PR +G+ P + G PG PG PG P + G G
Sbjct: 149 KGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQV 208
Query: 439 GGFP-------PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPK 491
G P PRGP+G +G GG G+ P P +
Sbjct: 209 GLMPGSVGPVGPRGPQGLQGQ-QGGAGPTGPPGEPGDPGP------------MGPIGSRG 255
Query: 492 PEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGM 549
PEG PP P G+ GR G G G G RG PG G G RG G G +G
Sbjct: 256 PEG--PPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKG- 312
Query: 550 DRGGFGGGRRGGPGGPPGPL-------MEQMGGRRGGRGGPGKMDKGEHRQERRDRP 599
+ G G GP GP G + M GR G +G PG+ +G H + P
Sbjct: 313 EVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQ--RGAHGMPGKPGP 367
Score = 40.0 bits (92), Expect = 0.006
Identities = 39/146 (26%), Positives = 49/146 (33%), Gaps = 14/146 (9%)
Query: 155 QNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQSSFRQ 213
Q G P G GQ+ G + P P + G P +G + Q
Sbjct: 1082 QGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQ 1141
Query: 214 D-HPSSMGVYG----------QESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRG 262
H G+ G Q S G GP R GP G + G + G
Sbjct: 1142 KGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSGKEG--NPGPLGPIGPP 1199
Query: 263 GGRGGMGSAGERGGFNKPGGPMDEGP 288
G RG +G AG G +PG P GP
Sbjct: 1200 GVRGSVGEAGPEGPPGEPGPPGPPGP 1225
Score = 37.7 bits (86), Expect = 0.030
Identities = 38/112 (33%), Positives = 42/112 (37%), Gaps = 11/112 (9%)
Query: 468 CP----NPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLM 523
CP PG GN NF K K E L P G G GP G +G RG
Sbjct: 93 CPVCSQTPGGGNTNFG-----RGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERG 147
Query: 524 DRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGG 575
+G PG RG +G D G+ G G GP G P QM G
Sbjct: 148 PKGRPGP--RGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAG 197
Score = 34.3 bits (77), Expect = 0.34
Identities = 38/158 (24%), Positives = 46/158 (29%), Gaps = 7/158 (4%)
Query: 148 DQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQA-----PSQYSQQS 202
D S+ + G G G GQ P P G+ Q P Q ++
Sbjct: 946 DPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERG 1005
Query: 203 SSYGQQSSFRQDHPSSMGVYGQES--GGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGG 260
+ G G + G PG N + P G G G
Sbjct: 1006 MPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVG 1065
Query: 261 RGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDP 298
G RG G AG G PG P G D G DP
Sbjct: 1066 ERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDP 1103
>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein
[Homo sapiens]
Length = 1650
Score = 90.1 bits (222), Expect = 5e-18
Identities = 118/396 (29%), Positives = 154/396 (38%), Gaps = 68/396 (17%)
Query: 216 PSSMGVYGQESG--GFSGPGENRSMSGPDNRG--RGRGGFDRGGMSRGGRGGGRGGMGSA 271
P S G+ G ESG G GP + ++GP + RGR G D G G G G
Sbjct: 418 PGSPGLKG-ESGDLGPQGPRGPQGLTGPPGKAGRRGRAGAD-------GARGMPGDPGVK 469
Query: 272 GERGGFNKPGGPMDEGPDLDLG------PPVDPDEDSDNSAIYVQGLNDSVTLDDLADFF 325
G+RG PG P ++G D G PP + E D+ I +GL L
Sbjct: 470 GDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPK 529
Query: 326 KQCGV-----VKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQ 380
G+ V+ P + E G P T + P + A+ K Q
Sbjct: 530 GPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQ 589
Query: 381 GSKLKVSLARKKPPMNSMRG--GLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG--- 435
G KP + M G G P G+ PP +G GP GP GP+G G RG
Sbjct: 590 G----------KPGLPGMPGSDGPPGHPGKEGPPGTKGNQ-GPSGPQGPLGYPGPRGVKG 638
Query: 436 --GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPE 493
G RG +G +G G P G++ + + PG ++ PE
Sbjct: 639 VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED-------------GPE 685
Query: 494 GFLPPPFPPPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGM 549
G P G G G GP G+ G +G L G PG R G G G GF G G
Sbjct: 686 G-------PKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASG- 737
Query: 550 DRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 585
++G G + GP G GP + G+RG RG GK
Sbjct: 738 EKGARGLSGKSGPRGERGPTGPR--GQRGPRGATGK 771
Score = 85.5 bits (210), Expect = 1e-16
Identities = 134/483 (27%), Positives = 173/483 (35%), Gaps = 85/483 (17%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQP---PTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDH 215
G P G Q + G+ G++ P P + G A + ++ G + +D
Sbjct: 836 GPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDP--GPPGAPGKDG 893
Query: 216 PSSM-GVYGQES--GGFSGPG--ENRSMSGPDNRGRGRGGFDRGGMSRGG------RGGG 264
P+ + G G+ G GPG N SGP G +RG GG R G
Sbjct: 894 PAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPG--ERGAAGSGGPIGPPGRPGP 951
Query: 265 RGGMGSAGERG--GFNKPGGPMD----EGP---DLDLGPPVDPDEDSDNSAIYVQGLNDS 315
+G G+AGE+G G P GP +GP GPP ED D + G +
Sbjct: 952 QGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGT 1011
Query: 316 VTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFD 375
K NK P G+P + P A+ F
Sbjct: 1012 ----------------KGNKGEHGPPGPPGPIGPVGQP---GAAGADGEPGARGPQGHFG 1052
Query: 376 GKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRG--------MPPPLRGGPGGPGGPG-- 425
K +G++ PP GLP G M PP GP GP GP
Sbjct: 1053 AKGDEGTR-----GFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGA 1107
Query: 426 -GPMGRMGGRG-----GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPG-CGNQNF 478
GP G GG G G++G G G +G P G R + PG G
Sbjct: 1108 DGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGP 1167
Query: 479 AWRTECNQCKA-PKPEGFLPPPFPP----------PGGDRGRGGPGGMRGGRGGLMDRGG 527
T + K P P GF P PP GDRG G G G G + G
Sbjct: 1168 KGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGP 1227
Query: 528 PGGMFRGGRGGDRG--GFRGGRGM--DRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGP 583
PG + + G G G G +GG+G D G G + GP GP GP + G G RG P
Sbjct: 1228 PGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKP--GPDGLRGLP 1285
Query: 584 GKM 586
G +
Sbjct: 1286 GSV 1288
Score = 83.6 bits (205), Expect = 5e-16
Identities = 125/453 (27%), Positives = 157/453 (34%), Gaps = 59/453 (13%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G P G + G Q G Q P YP G + + + F P
Sbjct: 605 GHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGF----PGF 660
Query: 219 MGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFN 278
G G + G+ + P +RG +G G G G MG G+ G
Sbjct: 661 KGDIGVK-------GDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG 713
Query: 279 KPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTG 338
PG P +GP LG P P + A + G + G TG
Sbjct: 714 LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSG---------------KSGPRGERGPTG 758
Query: 339 QPMIHIYLDKETGKPKGDATVSYEDP--PTAKAAVEWFDGKD-FQGSKLKVSLARKKPPM 395
P TGK T + P P + + G + F G K PP
Sbjct: 759 -PRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP--------KGPPG 809
Query: 396 NSMRGGLPPREGRGMPPPLRGGPGGPGGPG--GPMGRMGGRG--GDRGGFPPRGPRGSRG 451
+ GLP G+ +G G PG PG GP G G G G+RG P GP G +G
Sbjct: 810 PPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQG 869
Query: 452 NPSGGGNVQHRAGDWQCPNPG----CGNQNF-AWRTECNQCKAPKPEGFLPPPFPP---- 502
P G + PG G + F R P +G P PP
Sbjct: 870 LPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAG 929
Query: 503 PGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGP 562
G+RG G GG G G +G PG G G++G G G D G G GP
Sbjct: 930 SPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPI-GPTGRD-GVQGPVGLPGP 987
Query: 563 GGPPGPLMEQMGGRRGGRGGPG----KMDKGEH 591
GPPG E G +G G PG K +KGEH
Sbjct: 988 AGPPGVAGED--GDKGEVGDPGQKGTKGNKGEH 1018
Score = 82.0 bits (201), Expect = 1e-15
Identities = 134/469 (28%), Positives = 169/469 (36%), Gaps = 100/469 (21%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSY----GQQSSFRQD 214
G P S G+ G + G+ PT P G + Y G + S
Sbjct: 674 GVPGSRGED---GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSL--G 728
Query: 215 HPSSMGVYGQESG----GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGS 270
P G G++ G SGP R +GP + RG + G G GG G G
Sbjct: 729 FPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAK--GTSGGDGPHGP 786
Query: 271 AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGV 330
GERG PG G GPP P +D L Q G
Sbjct: 787 PGERG---LPGPQGPNGFPGPKGPPGPPGKDG------------------LPGHPGQRGE 825
Query: 331 VKMNKRTGQPMIHIYLDK-----ETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLK 385
V +TG P + ETG P G+ P + + GK+ G+K
Sbjct: 826 VGFQGKTGPPGPPGVVGPQGAAGETG-PMGERGHPGPPGPPGEQGLPGTAGKE--GTK-- 880
Query: 386 VSLARKKPPMNSMRGGLPPREG----RGMP-----PPLRGGPG-----GPGGPGGPMGRM 431
PP G P ++G RG P P GGPG GP GP GP G
Sbjct: 881 ---GDPGPP------GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSP 931
Query: 432 GGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKA 489
G RG G G P G G +G P AG+ P G + T + +
Sbjct: 932 GERGAAGSGGPIGPPGRPGPQGPPGA-------AGEKGVP----GEKGPIGPTGRDGVQG 980
Query: 490 PKPEGFLPPPFPPPG-----GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--- 541
P LP P PPG GD+G G G +G +G + G PG G G G
Sbjct: 981 PVG---LPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAG 1037
Query: 542 --GFRGGRGMDRGGFGG-GRRG--GPGGPPGPL-MEQMGGRRGGRGGPG 584
G G RG +G FG G G G GPPGP+ ++ + G G +G G
Sbjct: 1038 ADGEPGARG-PQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETG 1085
Score = 77.0 bits (188), Expect = 5e-14
Identities = 118/441 (26%), Positives = 149/441 (33%), Gaps = 104/441 (23%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQ-QSSSYGQQSSFRQDHPS 217
G G G + + G+ P P G Q + + + + G Q F
Sbjct: 998 GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHF------ 1051
Query: 218 SMGVYGQE-SGGFSGPGENRSMSG-PDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERG 275
G G E + GF+GP + G P G D G M G G RG G G G
Sbjct: 1052 --GAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADG 1109
Query: 276 GFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNK 335
PGG + LGPP + E ++ + +QG + GV
Sbjct: 1110 PQGPPGGVGN------LGPPGEKGEPGESGSPGIQG---------------EPGVKGPRG 1148
Query: 336 RTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPM 395
G+ KG++ E P DG P
Sbjct: 1149 ERGE--------------KGESGQPGEPGPPGPKGPTGDDG----------------PKG 1178
Query: 396 NSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG-----GRGGDRGGFPPRGPRGSR 450
N G P G PP GGP G G G G G G G G P GP G R
Sbjct: 1179 NPGPVGFPGDPG----PPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1234
Query: 451 GNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRG 510
G G+ + G +PG AP G + P G G+
Sbjct: 1235 GPAGSPGSEGRQGGKGAKGDPGA-------------IGAPGKTGPVGP-----AGPAGKP 1276
Query: 511 GPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRGGPG----- 563
GP G+RG G + +G PG + G G G G G RG D G G +G PG
Sbjct: 1277 GPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRG-DAG--AKGEKGHPGLIGLI 1333
Query: 564 GPPGPLMEQMGGRRGGRGGPG 584
GPPG EQ G +G RG PG
Sbjct: 1334 GPPG---EQ--GEKGDRGLPG 1349
Score = 72.0 bits (175), Expect = 1e-12
Identities = 107/432 (24%), Positives = 132/432 (30%), Gaps = 83/432 (19%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQSSFRQDHPS 217
G+P + G Q +G + G + P G PS ++ G P
Sbjct: 1040 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1099
Query: 218 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGF 277
G PG ++ P +G G G G RG G GE G
Sbjct: 1100 GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQP 1159
Query: 278 NKPGGPMDEGPDLDLGP---------PVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQC 328
+PG P +GP D GP P DP + G
Sbjct: 1160 GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGD------------- 1206
Query: 329 GVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSL 388
G+ D E G+P PP L
Sbjct: 1207 --------RGE-------DGEPGQPGSPGPTGENGPPGP--------------------L 1231
Query: 389 ARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG--GPMGRMGGRGGDRGGFPPRGP 446
++ P G P EGR +G PG G PG GP+G G G GP
Sbjct: 1232 GKRGP------AGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKP-------GP 1278
Query: 447 RGSRGNPSGGGNVQHRAGDWQCPNPG-CGNQNFAWRTECNQCKAPKPEGFLPPPFPPPG- 504
G RG P G Q PG G K K L PPG
Sbjct: 1279 DGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGE 1338
Query: 505 ----GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGR 558
GDRG GP G G +G + G G + GG G G G +G +G G G
Sbjct: 1339 QGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGE 1398
Query: 559 RG--GPGGPPGP 568
+G GP G PGP
Sbjct: 1399 KGVQGPPGHPGP 1410
Score = 65.9 bits (159), Expect = 1e-10
Identities = 124/476 (26%), Positives = 157/476 (32%), Gaps = 64/476 (13%)
Query: 155 QNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQD 214
+ + G P G G + G+ P TG Q + + S S
Sbjct: 724 KGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGP 783
Query: 215 H--PSSMGVYG-QESGGFSGPGENRSMSGPDNRG-----RGRGGFDRGGMSRGGRG---- 262
H P G+ G Q GF GP G D RG GF G G
Sbjct: 784 HGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGP 843
Query: 263 -GGRGGMGSAGERGGFNKPGGPMD---------EGPDLDLGPPVDPDEDSDNSAIYVQGL 312
G G G GERG PG P + EG D GPP P +D ++G
Sbjct: 844 QGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAG---LRGF 900
Query: 313 NDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVE 372
L A +K N+ P E G + P +
Sbjct: 901 PGERGLPGTAG----GPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPG 956
Query: 373 WFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG 432
K G K + + + GLP G PP + G G G G P G+ G
Sbjct: 957 AAGEKGVPGEKGPIGPTGRDGVQGPV--GLP---GPAGPPGVAGEDGDKGEVGDP-GQKG 1010
Query: 433 GRG--GDRGGFPPRGPRGSRGNPSGGG--------NVQHRAG--------DWQCPNPGCG 474
+G G+ G P GP G G P G Q G + P G
Sbjct: 1011 TKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIG 1070
Query: 475 NQNFAWRT-ECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFR 533
Q + E + P G PP P P G G G G +G GG+ + G PG
Sbjct: 1071 LQGLPGPSGEKGETGDVGPMG--PPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1128
Query: 534 GGRGGDRG-----GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPG 584
G G G G +G RG +RG G + G GPPGP + G G +G PG
Sbjct: 1129 PGESGSPGIQGEPGVKGPRG-ERGEKGESGQPGEPGPPGP--KGPTGDDGPKGNPG 1181
Score = 65.1 bits (157), Expect = 2e-10
Identities = 101/352 (28%), Positives = 118/352 (33%), Gaps = 62/352 (17%)
Query: 263 GGRGGMGSAGERG----GFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTL 318
G RG G GE G G P EGP +GPP +QG V
Sbjct: 291 GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPG------------IQGNPGPVGD 338
Query: 319 DDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKD 378
+ G+ + G P + L G GD K V
Sbjct: 339 PGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGD-----------KGPVVAAQEAQ 387
Query: 379 FQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPG--GPGGPGGPMGRMG--GR 434
Q + LA + PP G P G+ P L+G G GP GP GP G G G+
Sbjct: 388 AQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGK 447
Query: 435 GGDRG--------GFPP----RGPRGSRGNPSGGGNVQHRA--GDWQCPNPGCGNQNFAW 480
G RG G P +G RG G P G HR G P P +
Sbjct: 448 AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGD 507
Query: 481 RTECNQCKAPK---PEGFL----PPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFR 533
E P P G L PP P P G RG GP G +G G + G PG
Sbjct: 508 DGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT 567
Query: 534 GGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 585
G G G +G G GP G PG + M G G G PGK
Sbjct: 568 PGTQGLPG--------PQGAIGPHGEKGPQGKPG--LPGMPGSDGPPGHPGK 609
Score = 49.7 bits (117), Expect = 8e-06
Identities = 71/236 (30%), Positives = 83/236 (35%), Gaps = 67/236 (28%)
Query: 393 PPMNSMRGGLPPREG-RGMPPPLRGGP--GGPGGPGGPMGRMGGRGGDRGGFPPRGPRGS 449
PP+ G +G +G P L G GP GP GP G +G P G
Sbjct: 283 PPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIG-------------PPGI 329
Query: 450 RGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEG---FLPPPFPPPGGD 506
+GNP G+ R + PG AP P G LP F GGD
Sbjct: 330 QGNPGPVGDPGERGPPGRAGLPGSDG-------------APGPPGTSLMLPFRFGSGGGD 376
Query: 507 RG---------------------RGGPG--GMRGGRGGLMDRGGPGGMFRGGRGGDRG-- 541
+G RG PG G G G L G PG G GD G
Sbjct: 377 KGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPG---LKGESGDLGPQ 433
Query: 542 GFRGGRGMDRGGFGGGRRG-----GPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHR 592
G RG +G+ GRRG G G PG + G RG G PG + HR
Sbjct: 434 GPRGPQGLTGPPGKAGRRGRAGADGARGMPGD--PGVKGDRGFDGLPGLPGEKGHR 487
Score = 40.4 bits (93), Expect = 0.005
Identities = 72/294 (24%), Positives = 94/294 (31%), Gaps = 51/294 (17%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G+P G + G G P +P G + + Q + + P S
Sbjct: 1160 GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPR-GQDGAKGDRGEDGEPGQPGS 1218
Query: 219 MGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFN 278
G G+ +GP P G+ RG G G +GG G+ G+ G
Sbjct: 1219 PGPTGE-----NGP--------PGPLGK------RGPAGSPGSEGRQGGKGAKGDPGAIG 1259
Query: 279 KPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTG 338
PG GP GP P D ++GL SV Q G G
Sbjct: 1260 APGKTGPVGP---AGPAGKPGPDG------LRGLPGSVGQQGRPGATGQAGPPGPVGPPG 1310
Query: 339 QPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK-PPMNS 397
P + +GDA E + G+ QG K L + P
Sbjct: 1311 LPGL-----------RGDAGAKGEKGHPGLIGLIGPPGE--QGEKGDRGLPGPQGSPGQK 1357
Query: 398 MRGGLPPREGRGMP--PPLRGGPGGPGG------PGGPMGRMGGRGGDRGGFPP 443
G+P G P PP GP GP G PGGP G G +G PP
Sbjct: 1358 GEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPP 1411
>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein
[Homo sapiens]
Length = 1629
Score = 90.1 bits (222), Expect = 5e-18
Identities = 118/396 (29%), Positives = 154/396 (38%), Gaps = 68/396 (17%)
Query: 216 PSSMGVYGQESG--GFSGPGENRSMSGPDNRG--RGRGGFDRGGMSRGGRGGGRGGMGSA 271
P S G+ G ESG G GP + ++GP + RGR G D G G G G
Sbjct: 397 PGSPGLKG-ESGDLGPQGPRGPQGLTGPPGKAGRRGRAGAD-------GARGMPGDPGVK 448
Query: 272 GERGGFNKPGGPMDEGPDLDLG------PPVDPDEDSDNSAIYVQGLNDSVTLDDLADFF 325
G+RG PG P ++G D G PP + E D+ I +GL L
Sbjct: 449 GDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPK 508
Query: 326 KQCGV-----VKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQ 380
G+ V+ P + E G P T + P + A+ K Q
Sbjct: 509 GPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQ 568
Query: 381 GSKLKVSLARKKPPMNSMRG--GLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG--- 435
G KP + M G G P G+ PP +G GP GP GP+G G RG
Sbjct: 569 G----------KPGLPGMPGSDGPPGHPGKEGPPGTKGNQ-GPSGPQGPLGYPGPRGVKG 617
Query: 436 --GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPE 493
G RG +G +G G P G++ + + PG ++ PE
Sbjct: 618 VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED-------------GPE 664
Query: 494 GFLPPPFPPPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGM 549
G P G G G GP G+ G +G L G PG R G G G GF G G
Sbjct: 665 G-------PKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASG- 716
Query: 550 DRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 585
++G G + GP G GP + G+RG RG GK
Sbjct: 717 EKGARGLSGKSGPRGERGPTGPR--GQRGPRGATGK 750
Score = 85.5 bits (210), Expect = 1e-16
Identities = 134/483 (27%), Positives = 173/483 (35%), Gaps = 85/483 (17%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQP---PTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDH 215
G P G Q + G+ G++ P P + G A + ++ G + +D
Sbjct: 815 GPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDP--GPPGAPGKDG 872
Query: 216 PSSM-GVYGQES--GGFSGPG--ENRSMSGPDNRGRGRGGFDRGGMSRGG------RGGG 264
P+ + G G+ G GPG N SGP G +RG GG R G
Sbjct: 873 PAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPG--ERGAAGSGGPIGPPGRPGP 930
Query: 265 RGGMGSAGERG--GFNKPGGPMD----EGP---DLDLGPPVDPDEDSDNSAIYVQGLNDS 315
+G G+AGE+G G P GP +GP GPP ED D + G +
Sbjct: 931 QGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGT 990
Query: 316 VTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFD 375
K NK P G+P + P A+ F
Sbjct: 991 ----------------KGNKGEHGPPGPPGPIGPVGQP---GAAGADGEPGARGPQGHFG 1031
Query: 376 GKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRG--------MPPPLRGGPGGPGGPG-- 425
K +G++ PP GLP G M PP GP GP GP
Sbjct: 1032 AKGDEGTR-----GFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGA 1086
Query: 426 -GPMGRMGGRG-----GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPG-CGNQNF 478
GP G GG G G++G G G +G P G R + PG G
Sbjct: 1087 DGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGP 1146
Query: 479 AWRTECNQCKA-PKPEGFLPPPFPP----------PGGDRGRGGPGGMRGGRGGLMDRGG 527
T + K P P GF P PP GDRG G G G G + G
Sbjct: 1147 KGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGP 1206
Query: 528 PGGMFRGGRGGDRG--GFRGGRGM--DRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGP 583
PG + + G G G G +GG+G D G G + GP GP GP + G G RG P
Sbjct: 1207 PGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKP--GPDGLRGLP 1264
Query: 584 GKM 586
G +
Sbjct: 1265 GSV 1267
Score = 83.6 bits (205), Expect = 5e-16
Identities = 125/453 (27%), Positives = 157/453 (34%), Gaps = 59/453 (13%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G P G + G Q G Q P YP G + + + F P
Sbjct: 584 GHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGF----PGF 639
Query: 219 MGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFN 278
G G + G+ + P +RG +G G G G MG G+ G
Sbjct: 640 KGDIGVK-------GDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG 692
Query: 279 KPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTG 338
PG P +GP LG P P + A + G + G TG
Sbjct: 693 LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSG---------------KSGPRGERGPTG 737
Query: 339 QPMIHIYLDKETGKPKGDATVSYEDP--PTAKAAVEWFDGKD-FQGSKLKVSLARKKPPM 395
P TGK T + P P + + G + F G K PP
Sbjct: 738 -PRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP--------KGPPG 788
Query: 396 NSMRGGLPPREGRGMPPPLRGGPGGPGGPG--GPMGRMGGRG--GDRGGFPPRGPRGSRG 451
+ GLP G+ +G G PG PG GP G G G G+RG P GP G +G
Sbjct: 789 PPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQG 848
Query: 452 NPSGGGNVQHRAGDWQCPNPG----CGNQNF-AWRTECNQCKAPKPEGFLPPPFPP---- 502
P G + PG G + F R P +G P PP
Sbjct: 849 LPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAG 908
Query: 503 PGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGP 562
G+RG G GG G G +G PG G G++G G G D G G GP
Sbjct: 909 SPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPI-GPTGRD-GVQGPVGLPGP 966
Query: 563 GGPPGPLMEQMGGRRGGRGGPG----KMDKGEH 591
GPPG E G +G G PG K +KGEH
Sbjct: 967 AGPPGVAGED--GDKGEVGDPGQKGTKGNKGEH 997
Score = 82.0 bits (201), Expect = 1e-15
Identities = 134/469 (28%), Positives = 169/469 (36%), Gaps = 100/469 (21%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSY----GQQSSFRQD 214
G P S G+ G + G+ PT P G + Y G + S
Sbjct: 653 GVPGSRGED---GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSL--G 707
Query: 215 HPSSMGVYGQESG----GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGS 270
P G G++ G SGP R +GP + RG + G G GG G G
Sbjct: 708 FPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAK--GTSGGDGPHGP 765
Query: 271 AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGV 330
GERG PG G GPP P +D L Q G
Sbjct: 766 PGERG---LPGPQGPNGFPGPKGPPGPPGKDG------------------LPGHPGQRGE 804
Query: 331 VKMNKRTGQPMIHIYLDK-----ETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLK 385
V +TG P + ETG P G+ P + + GK+ G+K
Sbjct: 805 VGFQGKTGPPGPPGVVGPQGAAGETG-PMGERGHPGPPGPPGEQGLPGTAGKE--GTK-- 859
Query: 386 VSLARKKPPMNSMRGGLPPREG----RGMP-----PPLRGGPG-----GPGGPGGPMGRM 431
PP G P ++G RG P P GGPG GP GP GP G
Sbjct: 860 ---GDPGPP------GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSP 910
Query: 432 GGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKA 489
G RG G G P G G +G P AG+ P G + T + +
Sbjct: 911 GERGAAGSGGPIGPPGRPGPQGPPGA-------AGEKGVP----GEKGPIGPTGRDGVQG 959
Query: 490 PKPEGFLPPPFPPPG-----GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--- 541
P LP P PPG GD+G G G +G +G + G PG G G G
Sbjct: 960 PVG---LPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAG 1016
Query: 542 --GFRGGRGMDRGGFGG-GRRG--GPGGPPGPL-MEQMGGRRGGRGGPG 584
G G RG +G FG G G G GPPGP+ ++ + G G +G G
Sbjct: 1017 ADGEPGARG-PQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETG 1064
Score = 77.0 bits (188), Expect = 5e-14
Identities = 118/441 (26%), Positives = 149/441 (33%), Gaps = 104/441 (23%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQ-QSSSYGQQSSFRQDHPS 217
G G G + + G+ P P G Q + + + + G Q F
Sbjct: 977 GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHF------ 1030
Query: 218 SMGVYGQE-SGGFSGPGENRSMSG-PDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERG 275
G G E + GF+GP + G P G D G M G G RG G G G
Sbjct: 1031 --GAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADG 1088
Query: 276 GFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNK 335
PGG + LGPP + E ++ + +QG + GV
Sbjct: 1089 PQGPPGGVGN------LGPPGEKGEPGESGSPGIQG---------------EPGVKGPRG 1127
Query: 336 RTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPM 395
G+ KG++ E P DG P
Sbjct: 1128 ERGE--------------KGESGQPGEPGPPGPKGPTGDDG----------------PKG 1157
Query: 396 NSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG-----GRGGDRGGFPPRGPRGSR 450
N G P G PP GGP G G G G G G G G P GP G R
Sbjct: 1158 NPGPVGFPGDPG----PPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1213
Query: 451 GNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRG 510
G G+ + G +PG AP G + P G G+
Sbjct: 1214 GPAGSPGSEGRQGGKGAKGDPGA-------------IGAPGKTGPVGP-----AGPAGKP 1255
Query: 511 GPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRGGPG----- 563
GP G+RG G + +G PG + G G G G G RG D G G +G PG
Sbjct: 1256 GPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRG-DAG--AKGEKGHPGLIGLI 1312
Query: 564 GPPGPLMEQMGGRRGGRGGPG 584
GPPG EQ G +G RG PG
Sbjct: 1313 GPPG---EQ--GEKGDRGLPG 1328
Score = 72.0 bits (175), Expect = 1e-12
Identities = 107/432 (24%), Positives = 132/432 (30%), Gaps = 83/432 (19%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQSSFRQDHPS 217
G+P + G Q +G + G + P G PS ++ G P
Sbjct: 1019 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1078
Query: 218 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGF 277
G PG ++ P +G G G G RG G GE G
Sbjct: 1079 GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQP 1138
Query: 278 NKPGGPMDEGPDLDLGP---------PVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQC 328
+PG P +GP D GP P DP + G
Sbjct: 1139 GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGD------------- 1185
Query: 329 GVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSL 388
G+ D E G+P PP L
Sbjct: 1186 --------RGE-------DGEPGQPGSPGPTGENGPPGP--------------------L 1210
Query: 389 ARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG--GPMGRMGGRGGDRGGFPPRGP 446
++ P G P EGR +G PG G PG GP+G G G GP
Sbjct: 1211 GKRGP------AGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKP-------GP 1257
Query: 447 RGSRGNPSGGGNVQHRAGDWQCPNPG-CGNQNFAWRTECNQCKAPKPEGFLPPPFPPPG- 504
G RG P G Q PG G K K L PPG
Sbjct: 1258 DGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGE 1317
Query: 505 ----GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGR 558
GDRG GP G G +G + G G + GG G G G +G +G G G
Sbjct: 1318 QGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGE 1377
Query: 559 RG--GPGGPPGP 568
+G GP G PGP
Sbjct: 1378 KGVQGPPGHPGP 1389
Score = 65.9 bits (159), Expect = 1e-10
Identities = 124/476 (26%), Positives = 157/476 (32%), Gaps = 64/476 (13%)
Query: 155 QNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQD 214
+ + G P G G + G+ P TG Q + + S S
Sbjct: 703 KGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGP 762
Query: 215 H--PSSMGVYG-QESGGFSGPGENRSMSGPDNRG-----RGRGGFDRGGMSRGGRG---- 262
H P G+ G Q GF GP G D RG GF G G
Sbjct: 763 HGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGP 822
Query: 263 -GGRGGMGSAGERGGFNKPGGPMD---------EGPDLDLGPPVDPDEDSDNSAIYVQGL 312
G G G GERG PG P + EG D GPP P +D ++G
Sbjct: 823 QGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAG---LRGF 879
Query: 313 NDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVE 372
L A +K N+ P E G + P +
Sbjct: 880 PGERGLPGTAG----GPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPG 935
Query: 373 WFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG 432
K G K + + + GLP G PP + G G G G P G+ G
Sbjct: 936 AAGEKGVPGEKGPIGPTGRDGVQGPV--GLP---GPAGPPGVAGEDGDKGEVGDP-GQKG 989
Query: 433 GRG--GDRGGFPPRGPRGSRGNPSGGG--------NVQHRAG--------DWQCPNPGCG 474
+G G+ G P GP G G P G Q G + P G
Sbjct: 990 TKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIG 1049
Query: 475 NQNFAWRT-ECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFR 533
Q + E + P G PP P P G G G G +G GG+ + G PG
Sbjct: 1050 LQGLPGPSGEKGETGDVGPMG--PPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1107
Query: 534 GGRGGDRG-----GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPG 584
G G G G +G RG +RG G + G GPPGP + G G +G PG
Sbjct: 1108 PGESGSPGIQGEPGVKGPRG-ERGEKGESGQPGEPGPPGP--KGPTGDDGPKGNPG 1160
Score = 65.1 bits (157), Expect = 2e-10
Identities = 101/352 (28%), Positives = 118/352 (33%), Gaps = 62/352 (17%)
Query: 263 GGRGGMGSAGERG----GFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTL 318
G RG G GE G G P EGP +GPP +QG V
Sbjct: 270 GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPG------------IQGNPGPVGD 317
Query: 319 DDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKD 378
+ G+ + G P + L G GD K V
Sbjct: 318 PGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGD-----------KGPVVAAQEAQ 366
Query: 379 FQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPG--GPGGPGGPMGRMG--GR 434
Q + LA + PP G P G+ P L+G G GP GP GP G G G+
Sbjct: 367 AQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGK 426
Query: 435 GGDRG--------GFPP----RGPRGSRGNPSGGGNVQHRA--GDWQCPNPGCGNQNFAW 480
G RG G P +G RG G P G HR G P P +
Sbjct: 427 AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGD 486
Query: 481 RTECNQCKAPK---PEGFL----PPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFR 533
E P P G L PP P P G RG GP G +G G + G PG
Sbjct: 487 DGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGT 546
Query: 534 GGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 585
G G G +G G GP G PG + M G G G PGK
Sbjct: 547 PGTQGLPG--------PQGAIGPHGEKGPQGKPG--LPGMPGSDGPPGHPGK 588
Score = 40.4 bits (93), Expect = 0.005
Identities = 72/294 (24%), Positives = 94/294 (31%), Gaps = 51/294 (17%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G+P G + G G P +P G + + Q + + P S
Sbjct: 1139 GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPR-GQDGAKGDRGEDGEPGQPGS 1197
Query: 219 MGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFN 278
G G+ +GP P G+ RG G G +GG G+ G+ G
Sbjct: 1198 PGPTGE-----NGP--------PGPLGK------RGPAGSPGSEGRQGGKGAKGDPGAIG 1238
Query: 279 KPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTG 338
PG GP GP P D ++GL SV Q G G
Sbjct: 1239 APGKTGPVGP---AGPAGKPGPDG------LRGLPGSVGQQGRPGATGQAGPPGPVGPPG 1289
Query: 339 QPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK-PPMNS 397
P + +GDA E + G+ QG K L + P
Sbjct: 1290 LPGL-----------RGDAGAKGEKGHPGLIGLIGPPGE--QGEKGDRGLPGPQGSPGQK 1336
Query: 398 MRGGLPPREGRGMP--PPLRGGPGGPGG------PGGPMGRMGGRGGDRGGFPP 443
G+P G P PP GP GP G PGGP G G +G PP
Sbjct: 1337 GEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPP 1390
Score = 35.4 bits (80), Expect = 0.15
Identities = 40/122 (32%), Positives = 45/122 (36%), Gaps = 28/122 (22%)
Query: 494 GFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMD--- 550
G L P P G G GP G++G G + D G G R G G G G G
Sbjct: 287 GMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGA-PGPPGTSLML 345
Query: 551 --RGGFGGGRRG-------------------GPGGPPGPLMEQMGGRRGGRGGPGKMD-K 588
R G GGG +G GPPGP+ GR G G PG K
Sbjct: 346 PFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPM--GYTGRPGPLGQPGSPGLK 403
Query: 589 GE 590
GE
Sbjct: 404 GE 405
>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein
[Homo sapiens]
Length = 1736
Score = 90.1 bits (222), Expect = 5e-18
Identities = 118/396 (29%), Positives = 154/396 (38%), Gaps = 68/396 (17%)
Query: 216 PSSMGVYGQESG--GFSGPGENRSMSGPDNRG--RGRGGFDRGGMSRGGRGGGRGGMGSA 271
P S G+ G ESG G GP + ++GP + RGR G D G G G G
Sbjct: 504 PGSPGLKG-ESGDLGPQGPRGPQGLTGPPGKAGRRGRAGAD-------GARGMPGDPGVK 555
Query: 272 GERGGFNKPGGPMDEGPDLDLG------PPVDPDEDSDNSAIYVQGLNDSVTLDDLADFF 325
G+RG PG P ++G D G PP + E D+ I +GL L
Sbjct: 556 GDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPK 615
Query: 326 KQCGV-----VKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQ 380
G+ V+ P + E G P T + P + A+ K Q
Sbjct: 616 GPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQ 675
Query: 381 GSKLKVSLARKKPPMNSMRG--GLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG--- 435
G KP + M G G P G+ PP +G GP GP GP+G G RG
Sbjct: 676 G----------KPGLPGMPGSDGPPGHPGKEGPPGTKGNQ-GPSGPQGPLGYPGPRGVKG 724
Query: 436 --GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPE 493
G RG +G +G G P G++ + + PG ++ PE
Sbjct: 725 VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGED-------------GPE 771
Query: 494 GFLPPPFPPPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGM 549
G P G G G GP G+ G +G L G PG R G G G GF G G
Sbjct: 772 G-------PKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASG- 823
Query: 550 DRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 585
++G G + GP G GP + G+RG RG GK
Sbjct: 824 EKGARGLSGKSGPRGERGPTGPR--GQRGPRGATGK 857
Score = 85.5 bits (210), Expect = 1e-16
Identities = 134/483 (27%), Positives = 173/483 (35%), Gaps = 85/483 (17%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQP---PTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDH 215
G P G Q + G+ G++ P P + G A + ++ G + +D
Sbjct: 922 GPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDP--GPPGAPGKDG 979
Query: 216 PSSM-GVYGQES--GGFSGPG--ENRSMSGPDNRGRGRGGFDRGGMSRGG------RGGG 264
P+ + G G+ G GPG N SGP G +RG GG R G
Sbjct: 980 PAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPG--ERGAAGSGGPIGPPGRPGP 1037
Query: 265 RGGMGSAGERG--GFNKPGGPMD----EGP---DLDLGPPVDPDEDSDNSAIYVQGLNDS 315
+G G+AGE+G G P GP +GP GPP ED D + G +
Sbjct: 1038 QGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGT 1097
Query: 316 VTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFD 375
K NK P G+P + P A+ F
Sbjct: 1098 ----------------KGNKGEHGPPGPPGPIGPVGQP---GAAGADGEPGARGPQGHFG 1138
Query: 376 GKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRG--------MPPPLRGGPGGPGGPG-- 425
K +G++ PP GLP G M PP GP GP GP
Sbjct: 1139 AKGDEGTR-----GFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGA 1193
Query: 426 -GPMGRMGGRG-----GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPG-CGNQNF 478
GP G GG G G++G G G +G P G R + PG G
Sbjct: 1194 DGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGP 1253
Query: 479 AWRTECNQCKA-PKPEGFLPPPFPP----------PGGDRGRGGPGGMRGGRGGLMDRGG 527
T + K P P GF P PP GDRG G G G G + G
Sbjct: 1254 KGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGP 1313
Query: 528 PGGMFRGGRGGDRG--GFRGGRGM--DRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGP 583
PG + + G G G G +GG+G D G G + GP GP GP + G G RG P
Sbjct: 1314 PGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKP--GPDGLRGLP 1371
Query: 584 GKM 586
G +
Sbjct: 1372 GSV 1374
Score = 83.6 bits (205), Expect = 5e-16
Identities = 125/453 (27%), Positives = 157/453 (34%), Gaps = 59/453 (13%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G P G + G Q G Q P YP G + + + F P
Sbjct: 691 GHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGF----PGF 746
Query: 219 MGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFN 278
G G + G+ + P +RG +G G G G MG G+ G
Sbjct: 747 KGDIGVK-------GDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG 799
Query: 279 KPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTG 338
PG P +GP LG P P + A + G + G TG
Sbjct: 800 LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSG---------------KSGPRGERGPTG 844
Query: 339 QPMIHIYLDKETGKPKGDATVSYEDP--PTAKAAVEWFDGKD-FQGSKLKVSLARKKPPM 395
P TGK T + P P + + G + F G K PP
Sbjct: 845 -PRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGP--------KGPPG 895
Query: 396 NSMRGGLPPREGRGMPPPLRGGPGGPGGPG--GPMGRMGGRG--GDRGGFPPRGPRGSRG 451
+ GLP G+ +G G PG PG GP G G G G+RG P GP G +G
Sbjct: 896 PPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQG 955
Query: 452 NPSGGGNVQHRAGDWQCPNPG----CGNQNF-AWRTECNQCKAPKPEGFLPPPFPP---- 502
P G + PG G + F R P +G P PP
Sbjct: 956 LPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAG 1015
Query: 503 PGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGP 562
G+RG G GG G G +G PG G G++G G G D G G GP
Sbjct: 1016 SPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPI-GPTGRD-GVQGPVGLPGP 1073
Query: 563 GGPPGPLMEQMGGRRGGRGGPG----KMDKGEH 591
GPPG E G +G G PG K +KGEH
Sbjct: 1074 AGPPGVAGED--GDKGEVGDPGQKGTKGNKGEH 1104
Score = 82.0 bits (201), Expect = 1e-15
Identities = 134/469 (28%), Positives = 169/469 (36%), Gaps = 100/469 (21%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSY----GQQSSFRQD 214
G P S G+ G + G+ PT P G + Y G + S
Sbjct: 760 GVPGSRGED---GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSL--G 814
Query: 215 HPSSMGVYGQESG----GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGS 270
P G G++ G SGP R +GP + RG + G G GG G G
Sbjct: 815 FPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAK--GTSGGDGPHGP 872
Query: 271 AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGV 330
GERG PG G GPP P +D L Q G
Sbjct: 873 PGERG---LPGPQGPNGFPGPKGPPGPPGKDG------------------LPGHPGQRGE 911
Query: 331 VKMNKRTGQPMIHIYLDK-----ETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLK 385
V +TG P + ETG P G+ P + + GK+ G+K
Sbjct: 912 VGFQGKTGPPGPPGVVGPQGAAGETG-PMGERGHPGPPGPPGEQGLPGTAGKE--GTK-- 966
Query: 386 VSLARKKPPMNSMRGGLPPREG----RGMP-----PPLRGGPG-----GPGGPGGPMGRM 431
PP G P ++G RG P P GGPG GP GP GP G
Sbjct: 967 ---GDPGPP------GAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSP 1017
Query: 432 GGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKA 489
G RG G G P G G +G P AG+ P G + T + +
Sbjct: 1018 GERGAAGSGGPIGPPGRPGPQGPPGA-------AGEKGVP----GEKGPIGPTGRDGVQG 1066
Query: 490 PKPEGFLPPPFPPPG-----GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--- 541
P LP P PPG GD+G G G +G +G + G PG G G G
Sbjct: 1067 PVG---LPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAG 1123
Query: 542 --GFRGGRGMDRGGFGG-GRRG--GPGGPPGPL-MEQMGGRRGGRGGPG 584
G G RG +G FG G G G GPPGP+ ++ + G G +G G
Sbjct: 1124 ADGEPGARG-PQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETG 1171
Score = 77.0 bits (188), Expect = 5e-14
Identities = 118/441 (26%), Positives = 149/441 (33%), Gaps = 104/441 (23%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQ-QSSSYGQQSSFRQDHPS 217
G G G + + G+ P P G Q + + + + G Q F
Sbjct: 1084 GDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHF------ 1137
Query: 218 SMGVYGQE-SGGFSGPGENRSMSG-PDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERG 275
G G E + GF+GP + G P G D G M G G RG G G G
Sbjct: 1138 --GAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADG 1195
Query: 276 GFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNK 335
PGG + LGPP + E ++ + +QG + GV
Sbjct: 1196 PQGPPGGVGN------LGPPGEKGEPGESGSPGIQG---------------EPGVKGPRG 1234
Query: 336 RTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPM 395
G+ KG++ E P DG P
Sbjct: 1235 ERGE--------------KGESGQPGEPGPPGPKGPTGDDG----------------PKG 1264
Query: 396 NSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG-----GRGGDRGGFPPRGPRGSR 450
N G P G PP GGP G G G G G G G G P GP G R
Sbjct: 1265 NPGPVGFPGDPG----PPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKR 1320
Query: 451 GNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRG 510
G G+ + G +PG AP G + P G G+
Sbjct: 1321 GPAGSPGSEGRQGGKGAKGDPGA-------------IGAPGKTGPVGP-----AGPAGKP 1362
Query: 511 GPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRGGPG----- 563
GP G+RG G + +G PG + G G G G G RG D G G +G PG
Sbjct: 1363 GPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRG-DAG--AKGEKGHPGLIGLI 1419
Query: 564 GPPGPLMEQMGGRRGGRGGPG 584
GPPG EQ G +G RG PG
Sbjct: 1420 GPPG---EQ--GEKGDRGLPG 1435
Score = 72.0 bits (175), Expect = 1e-12
Identities = 107/432 (24%), Positives = 132/432 (30%), Gaps = 83/432 (19%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQSSFRQDHPS 217
G+P + G Q +G + G + P G PS ++ G P
Sbjct: 1126 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1185
Query: 218 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGF 277
G PG ++ P +G G G G RG G GE G
Sbjct: 1186 GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQP 1245
Query: 278 NKPGGPMDEGPDLDLGP---------PVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQC 328
+PG P +GP D GP P DP + G
Sbjct: 1246 GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGD------------- 1292
Query: 329 GVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSL 388
G+ D E G+P PP L
Sbjct: 1293 --------RGE-------DGEPGQPGSPGPTGENGPPGP--------------------L 1317
Query: 389 ARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG--GPMGRMGGRGGDRGGFPPRGP 446
++ P G P EGR +G PG G PG GP+G G G GP
Sbjct: 1318 GKRGP------AGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKP-------GP 1364
Query: 447 RGSRGNPSGGGNVQHRAGDWQCPNPG-CGNQNFAWRTECNQCKAPKPEGFLPPPFPPPG- 504
G RG P G Q PG G K K L PPG
Sbjct: 1365 DGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGE 1424
Query: 505 ----GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGR 558
GDRG GP G G +G + G G + GG G G G +G +G G G
Sbjct: 1425 QGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGE 1484
Query: 559 RG--GPGGPPGP 568
+G GP G PGP
Sbjct: 1485 KGVQGPPGHPGP 1496
Score = 67.0 bits (162), Expect = 5e-11
Identities = 124/515 (24%), Positives = 168/515 (32%), Gaps = 96/515 (18%)
Query: 109 QASYAAQSAYGTQPA--YPAYGQQPAATAPTS-YSSTQPTSYDQSSYSQQNTYGQPSSYG 165
Q + AQ + QP+ + Q+P + S Y +P YD + Y P+
Sbjct: 239 QQPHRAQRSPQQQPSRLHRPQNQEPQSQPTESLYYDYEPPYYDVMTTGTTPDYQDPTPGE 298
Query: 166 QQS--------SYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQ--QSSSYGQQSSFRQDH 215
++ ++ + Q PPT+ Q Y + + + +YG +R++
Sbjct: 299 EEEILESSLLPPLEEEQTDLQVPPTADRFQAEEYGEGGTDPPEGPYDYTYGYGDDYREET 358
Query: 216 PSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERG 275
+ + + + R + G +G GM G G G G G G
Sbjct: 359 ELGPALSAETAHSGAAAHGPRGLKGE----KGEPAVLEPGMLVEGPPGPEGPAGLIGPPG 414
Query: 276 GFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNK 335
PG D G + GPP + G+ +
Sbjct: 415 IQGNPGPVGDPG---ERGPP------------------------------GRAGLPGSDG 441
Query: 336 RTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPM 395
G P + L G GD K V Q + LA + PP
Sbjct: 442 APGPPGTSLMLPFRFGSGGGD-----------KGPVVAAQEAQAQAILQQARLALRGPPG 490
Query: 396 NSMRGGLPPREGRGMPPPLRGGPG--GPGGPGGPMGRMG--GRGGDRG--------GFPP 443
G P G+ P L+G G GP GP GP G G G+ G RG G P
Sbjct: 491 PMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPG 550
Query: 444 ----RGPRGSRGNPSGGGNVQHRA--GDWQCPNPGCGNQNFAWRTECNQCKAPK---PEG 494
+G RG G P G HR G P P + E P P G
Sbjct: 551 DPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRG 610
Query: 495 FL----PPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMD 550
L PP P P G RG GP G +G G + G PG G G G
Sbjct: 611 LLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPG--------P 662
Query: 551 RGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 585
+G G GP G PG + M G G G PGK
Sbjct: 663 QGAIGPHGEKGPQGKPG--LPGMPGSDGPPGHPGK 695
Score = 65.9 bits (159), Expect = 1e-10
Identities = 124/476 (26%), Positives = 157/476 (32%), Gaps = 64/476 (13%)
Query: 155 QNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQD 214
+ + G P G G + G+ P TG Q + + S S
Sbjct: 810 KGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGP 869
Query: 215 H--PSSMGVYG-QESGGFSGPGENRSMSGPDNRG-----RGRGGFDRGGMSRGGRG---- 262
H P G+ G Q GF GP G D RG GF G G
Sbjct: 870 HGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGP 929
Query: 263 -GGRGGMGSAGERGGFNKPGGPMD---------EGPDLDLGPPVDPDEDSDNSAIYVQGL 312
G G G GERG PG P + EG D GPP P +D ++G
Sbjct: 930 QGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAG---LRGF 986
Query: 313 NDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVE 372
L A +K N+ P E G + P +
Sbjct: 987 PGERGLPGTAG----GPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPG 1042
Query: 373 WFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG 432
K G K + + + GLP G PP + G G G G P G+ G
Sbjct: 1043 AAGEKGVPGEKGPIGPTGRDGVQGPV--GLP---GPAGPPGVAGEDGDKGEVGDP-GQKG 1096
Query: 433 GRG--GDRGGFPPRGPRGSRGNPSGGG--------NVQHRAG--------DWQCPNPGCG 474
+G G+ G P GP G G P G Q G + P G
Sbjct: 1097 TKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIG 1156
Query: 475 NQNFAWRT-ECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFR 533
Q + E + P G PP P P G G G G +G GG+ + G PG
Sbjct: 1157 LQGLPGPSGEKGETGDVGPMG--PPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1214
Query: 534 GGRGGDRG-----GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPG 584
G G G G +G RG +RG G + G GPPGP + G G +G PG
Sbjct: 1215 PGESGSPGIQGEPGVKGPRG-ERGEKGESGQPGEPGPPGP--KGPTGDDGPKGNPG 1267
Score = 40.4 bits (93), Expect = 0.005
Identities = 72/294 (24%), Positives = 94/294 (31%), Gaps = 51/294 (17%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G+P G + G G P +P G + + Q + + P S
Sbjct: 1246 GEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPR-GQDGAKGDRGEDGEPGQPGS 1304
Query: 219 MGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFN 278
G G+ +GP P G+ RG G G +GG G+ G+ G
Sbjct: 1305 PGPTGE-----NGP--------PGPLGK------RGPAGSPGSEGRQGGKGAKGDPGAIG 1345
Query: 279 KPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTG 338
PG GP GP P D ++GL SV Q G G
Sbjct: 1346 APGKTGPVGP---AGPAGKPGPDG------LRGLPGSVGQQGRPGATGQAGPPGPVGPPG 1396
Query: 339 QPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK-PPMNS 397
P + +GDA E + G+ QG K L + P
Sbjct: 1397 LPGL-----------RGDAGAKGEKGHPGLIGLIGPPGE--QGEKGDRGLPGPQGSPGQK 1443
Query: 398 MRGGLPPREGRGMP--PPLRGGPGGPGG------PGGPMGRMGGRGGDRGGFPP 443
G+P G P PP GP GP G PGGP G G +G PP
Sbjct: 1444 GEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPGHPGPP 1497
Score = 36.2 bits (82), Expect = 0.089
Identities = 56/199 (28%), Positives = 64/199 (32%), Gaps = 44/199 (22%)
Query: 417 GPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQ 476
G GG P GP G G D GP S G G
Sbjct: 333 GEGGTDPPEGPYDYTYGYGDDYREETELGPALSAETAHSGAAAHGPRG------------ 380
Query: 477 NFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGR 536
+ E + +P G L P P G G GP G++G G + D G G R G
Sbjct: 381 ---LKGEKGEPAVLEP-GMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGL 436
Query: 537 GGDRGGFRGGRGMD-----RGGFGGGRRG-------------------GPGGPPGPLMEQ 572
G G G G R G GGG +G GPPGP+
Sbjct: 437 PGSDGA-PGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPM--G 493
Query: 573 MGGRRGGRGGPGKMD-KGE 590
GR G G PG KGE
Sbjct: 494 YTGRPGPLGQPGSPGLKGE 512
>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
sapiens]
Length = 1818
Score = 89.7 bits (221), Expect = 7e-18
Identities = 130/482 (26%), Positives = 162/482 (33%), Gaps = 118/482 (24%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQ----------APSQYSQQSSSYGQQ 208
G+P GQQ + G Q G Q P P + G + P + + G++
Sbjct: 697 GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK 756
Query: 209 SSFRQD-------HPSSMGVYGQ-----------ESGGFSGPGENRSMSGPDNRG----- 245
+ +P GV G E G PG M +RG
Sbjct: 757 GALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQI 816
Query: 246 --RGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPG---GPMDEGPDLDLGPPVDPDE 300
RG G G R G G G G AGE+G PG P +GP G P P
Sbjct: 817 GPRGEDG-PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGA 875
Query: 301 DSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVS 360
+ + A V G + G TG P TGKP T
Sbjct: 876 NGEKGARGVAG---------------KPGPRGQRGPTG-PRGSRGARGPTGKPGPKGTSG 919
Query: 361 YEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK-PPMNSMRGGLPPREGRGMPPPLRG--G 417
+ PP + QG + V K PP + GLP G+ +G G
Sbjct: 920 GDGPPGPPGE------RGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 973
Query: 418 PGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGN 475
P GPGG GP G G G G+RG P GP G +G P G + GD
Sbjct: 974 PPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK-EGAKGD---------- 1022
Query: 476 QNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGG 535
P P G G+ GP G+RG G +RG PG G
Sbjct: 1023 -------------------------PGPQGISGKDGPAGLRGFPG---ERGLPGAQGAPG 1054
Query: 536 RGGDRG-----------GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQ-MGGRRGGRGGP 583
G G G RG G G G R GP GPPGP E+ G +G +G
Sbjct: 1055 LKGGEGPQGPPGPVGSPGERGSAGT-AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPA 1113
Query: 584 GK 585
G+
Sbjct: 1114 GR 1115
Score = 85.1 bits (209), Expect = 2e-16
Identities = 123/451 (27%), Positives = 159/451 (35%), Gaps = 44/451 (9%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGS--YSQAPSQYSQQSSSYGQQSSFRQDHP 216
G+ G+ G G Q PT G + P +Q + P
Sbjct: 964 GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP 1023
Query: 217 SSMGVYGQES-GGFSG-PGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGER 274
G+ G++ G G PGE R + G +GG G G G G GSAG
Sbjct: 1024 GPQGISGKDGPAGLRGFPGE-RGLPGAQGAPGLKGG--EGPQGPPGPVGSPGERGSAGTA 1080
Query: 275 GGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMN 334
G PG P +GP G P E G+ V L A G
Sbjct: 1081 GPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1140
Query: 335 KRTGQP-MIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKP 393
G+P DK P G + P + DG+ G + + + +K
Sbjct: 1141 GEIGEPGQKGSKGDKGENGPPGPPGLQ---GPVGAPGIAGGDGEP--GPRGQQGMFGQKG 1195
Query: 394 PMNSMRGGLPPR----EGRGMPPPLRG-----GPGGPGGPGGPMGRMGGRGGDRGGFPPR 444
+ PP +G PP +G GP GP GP GP G G G D P+
Sbjct: 1196 DEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGAD----GPQ 1251
Query: 445 GPRGSRGNPSGGGNVQHRAGDWQCPNP----GCGNQNFAWRTECNQCKAPKPEGFLPPPF 500
GP GS G+ G G + G+ P P G G + E + P G PP
Sbjct: 1252 GPPGSVGSVGGVGE-KGEPGEAGNPGPPGEAGVGGP----KGERGEKGEAGPPGAAGPPG 1306
Query: 501 P--PPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGR 558
PPG D +G PG + G G G PG + G GGD+G G G G
Sbjct: 1307 AKGPPGDDGPKGNPGPV-GFPGDPGPPGEPGPAGQDGVGGDKG--EDGDPGQPGPPGPSG 1363
Query: 559 RGGPGGPPG----PLMEQMGGRRGGRGGPGK 585
GP GPPG P GR+G +G G+
Sbjct: 1364 EAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1394
Score = 82.8 bits (203), Expect = 8e-16
Identities = 144/478 (30%), Positives = 185/478 (38%), Gaps = 74/478 (15%)
Query: 149 QSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQA-PSQYSQQSSSYGQ 207
+ S ++ G P G G + GQ P G +A P+ S G+
Sbjct: 786 KGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGE 845
Query: 208 QSSFR----QDHPSSMGVYGQESGGFSG-PGEN-----RSMSG-PDNRGRGRGGFDRGGM 256
+ +P G G S GF G PG N R ++G P RG+ RG
Sbjct: 846 KGKLGVPGLPGYPGRQGPKG--STGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRG-- 901
Query: 257 SRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSV 316
SRG RG G G G GG PG P + GP GP P +G
Sbjct: 902 SRGARGP-TGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP---------KGPPGPP 951
Query: 317 TLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKE--TGK--PKGDATVSYEDPPTAKAAVE 372
D L Q G +TG P + + TG+ P G+ P + +
Sbjct: 952 GKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLP 1011
Query: 373 WFDGKD-FQGSKLKVSLARKKPPMNSMRG-----GLPPREGRGMPPPLRGGPGGPGGPGG 426
GK+ +G ++ K P +RG GLP +G P L+GG G P GP G
Sbjct: 1012 GAAGKEGAKGDPGPQGISGKDGPAG-LRGFPGERGLPGAQGA---PGLKGGEG-PQGPPG 1066
Query: 427 PMGRMGGRG--GDRG--GFPPR-GPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWR 481
P+G G RG G G G P R GP+G G P+G G Q P G Q
Sbjct: 1067 PVGSPGERGSAGTAGPIGLPGRPGPQGPPG-PAGEKGAPGEKGP-QGPAGRDGVQG---- 1120
Query: 482 TECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRG--GPGGM-----FRG 534
P P G P P GD+G G G +G +G + G GP G+ G
Sbjct: 1121 ----PVGLPGPAG--PAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPG 1174
Query: 535 GRGGD-RGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEH 591
GGD G RG +GM G RG P GPPGP+ G +G G PG +KGE+
Sbjct: 1175 IAGGDGEPGPRGQQGMFGQKGDEGARGFP-GPPGPI-----GLQGLPGPPG--EKGEN 1224
Score = 80.5 bits (197), Expect = 4e-15
Identities = 113/373 (30%), Positives = 140/373 (37%), Gaps = 105/373 (28%)
Query: 254 GGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLN 313
G M GR G GG GS+G +G + G P +GP GPP
Sbjct: 544 GPMGLTGRPGPVGGPGSSGAKG---ESGDPGPQGPRGVQGPPGP---------------- 584
Query: 314 DSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEW 373
TG+P + G+P D P AK
Sbjct: 585 -----------------------TGKP-------GKRGRPGADGGRGMPGEPGAKGD-RG 613
Query: 374 FDG-------KDFQGSKLKVSLARKKPPMNSMRG--------GLPPREG-RGMPPPLRGG 417
FDG K +G + P + MRG GLP G RG+ P RG
Sbjct: 614 FDGLPGLPGDKGHRGERGPQG-PPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGP-RGT 671
Query: 418 PGGPGGPG--------GPMGRMGGRG-----GDRGGFPPRGPRGSRG--NPSGGGNVQHR 462
PG PG PG GP G MG +G G +G P+G G +G P G Q +
Sbjct: 672 PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 731
Query: 463 AG-------DWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGM 515
G D +PG Q+ E P P+G P +P P G +G G G+
Sbjct: 732 PGLAGLPGADGPPGHPGKEGQS----GEKGALGPPGPQG--PIGYPGPRGVKGADGVRGL 785
Query: 516 RGGRGGLMDRGGPGGMFRGGRG--GDRG--GFRGGRGMDRGGFGGGRRGGPGGPPGPLME 571
+G +G + G PG F+G G GDRG G G RG D G G R GP G PGP
Sbjct: 786 KGSKGEKGEDGFPG--FKGDMGLKGDRGEVGQIGPRGED-GPEGPKGRAGPTGDPGP--S 840
Query: 572 QMGGRRGGRGGPG 584
G +G G PG
Sbjct: 841 GQAGEKGKLGVPG 853
Score = 78.6 bits (192), Expect = 2e-14
Identities = 131/503 (26%), Positives = 171/503 (33%), Gaps = 77/503 (15%)
Query: 130 QPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTG 189
+P S + S D + G P G+ G+ + G + P G
Sbjct: 551 RPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKG 610
Query: 190 S--YSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESG----GFSGPGENRSMSGPDN 243
+ P + + P G+ G++ G G R + GP
Sbjct: 611 DRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGP-- 668
Query: 244 RGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSD 303
RG G G G +G MG GE G + G P +G GP P E
Sbjct: 669 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 728
Query: 304 NSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYED 363
+ GL AD G + GQ L G P + Y
Sbjct: 729 QGKPGLAGLPG-------AD-----GPPGHPGKEGQSGEKGAL----GPPGPQGPIGYPG 772
Query: 364 PPTAKAAVEWFDG-KDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPG 422
P K A DG + +GSK + + + +G + + RG + GP G
Sbjct: 773 PRGVKGA----DGVRGLKGSKGE----KGEDGFPGFKGDMGLKGDRGEVGQI--GPRGED 822
Query: 423 GPGGPMGRMG--------GRGGDRG--------GFPPR-GPRGSRGNPSGGGNVQHRAGD 465
GP GP GR G G+ G++G G+P R GP+GS G P G +
Sbjct: 823 GPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGAR 882
Query: 466 WQCPNPGCGNQN-----FAWRTECNQCKAPKPEGFLPPPFPP-PGGDRGRGGPGGMRGGR 519
PG Q R P P+G PP P G+RG GP G G
Sbjct: 883 GVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFP 942
Query: 520 GGLMDRGGPGGMFRGGRGGDRG--GFRGGRG-MDRGGFGG-----------GRRGGPGGP 565
G G PG G G RG GF+G G GG G G RG P GP
Sbjct: 943 GPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHP-GP 1001
Query: 566 PGPLMEQ----MGGRRGGRGGPG 584
PGP EQ G+ G +G PG
Sbjct: 1002 PGPPGEQGLPGAAGKEGAKGDPG 1024
Score = 78.6 bits (192), Expect = 2e-14
Identities = 120/404 (29%), Positives = 151/404 (37%), Gaps = 84/404 (20%)
Query: 216 PSSMGVYGQESGGFSGPGENRSMSGPDNRG-----RGRGGFDRG-GM-----SRGGRG-- 262
P S G G+ G GP R + GP RGR G D G GM ++G RG
Sbjct: 558 PGSSGAKGES--GDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFD 615
Query: 263 ---GGRGGMGSAGERGGFNKPGGPMDE---GPDLDLGPPVDPDEDSDNSAIYVQGLNDSV 316
G G G GERG PG P D+ G D ++GP P E + +G +
Sbjct: 616 GLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGA- 674
Query: 317 TLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDG 376
GQP + +D G PKG+ E P +
Sbjct: 675 --------------------PGQPGM-AGVDGPPG-PKGNMGPQGEPGPPGQ-------- 704
Query: 377 KDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGG 436
QG+ L + P+ G P +G P L G PG G PG P G+ G
Sbjct: 705 ---QGNPGPQGLPGPQGPI-----GPPGEKGPQGKPGLAGLPGADGPPGHP--GKEGQSG 754
Query: 437 DRGGFPPRGPRGSRGNP-----SGGGNVQHRAGD----WQCPNPGC-GNQNFAW-RTECN 485
++G P GP+G G P G V+ G + PG G+ R E
Sbjct: 755 EKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG 814
Query: 486 QCKAPKPEGFLPPPFPPPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-- 541
Q +G P P G G G GP G G +G L G PG R G G G
Sbjct: 815 QIGPRGEDG----PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 870
Query: 542 GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 585
GF G G ++G G + GP G GP + G RG RG GK
Sbjct: 871 GFPGANG-EKGARGVAGKPGPRGQRGPTGPR--GSRGARGPTGK 911
Score = 77.0 bits (188), Expect = 5e-14
Identities = 131/464 (28%), Positives = 171/464 (36%), Gaps = 111/464 (23%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G+ + G++ G G Q P P G P+ + G+ P
Sbjct: 1099 GEKGAPGEKGPQGPAGRDGVQGPVGLPGPAG-----PAGSPGEDGDKGEIGE-----PGQ 1148
Query: 219 MGVYGQ--ESG-----GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSA 271
G G E+G G GP ++G D RG +G + G G RG G
Sbjct: 1149 KGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRG--QQGMFGQKGDEGARGFPGPP 1206
Query: 272 GERGGFNKPGGPMDEGPDLDLGPPVDPDE------DSDNSAIYVQGLNDSVTLDDLADFF 325
G G PG P ++G + D+GP P N A QG SV
Sbjct: 1207 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV--------- 1257
Query: 326 KQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLK 385
G V G+P E G P P +A V G+ +G K +
Sbjct: 1258 ---GSVGGVGEKGEP-------GEAGNPG----------PPGEAGVGGPKGE--RGEKGE 1295
Query: 386 VSLARKKPPMNSMRGGLPPREG-RGMPPPLRGGPGGPGGPG--GPMGRMGGRGGDRG--- 439
P + G P +G +G P P+ G PG PG PG GP G+ G GGD+G
Sbjct: 1296 AGPPGAAGPPGAK--GPPGDDGPKGNPGPV-GFPGDPGPPGEPGPAGQ-DGVGGDKGEDG 1351
Query: 440 --GFP----------PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQC 487
G P P GP G RG P G + R G+ + +
Sbjct: 1352 DPGQPGPPGPSGEAGPPGPPGKRG-PPGAAGAEGRQGE---------------KGAKGEA 1395
Query: 488 KAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRG 545
A P G P P G G+ GP G+RG G + ++G PG + G G G G G
Sbjct: 1396 GAEGPPGKTGPVGPQ--GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPG 1453
Query: 546 GRGMDRGGFGGGRRGGPG-----GPPGPLMEQMGGRRGGRGGPG 584
+G D G G +G PG GPPG EQ G +G RG PG
Sbjct: 1454 LKG-DPG--SKGEKGHPGLIGLIGPPG---EQ--GEKGDRGLPG 1489
Score = 70.9 bits (172), Expect = 3e-12
Identities = 122/456 (26%), Positives = 154/456 (33%), Gaps = 62/456 (13%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G P + G G + G P P + GS A
Sbjct: 1045 GLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTA----------------------GP 1082
Query: 219 MGVYGQESGGFSGPGENRSMSGPDNRG-RGRGGFD--RGGMSRGGRGGGRGGMGSAGERG 275
+G+ G+ G PG P +G +G G D +G + G G G G G++G
Sbjct: 1083 IGLPGRP-GPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKG 1141
Query: 276 GFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNK 335
+PG +G + GPP P A + G + F Q G
Sbjct: 1142 EIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARG 1201
Query: 336 RTGQPMIHIYLDKETGKP-----KGDATVSYEDPPTAKAAVEWFDGKDF-QGSKLKVS-- 387
G P I L G P GD P + +G D QG V
Sbjct: 1202 FPGPPG-PIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSV 1260
Query: 388 --LARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG--GDRGGFPP 443
+ K P + G P G G P RG G GP G G G +G GD G
Sbjct: 1261 GGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKG-EAGPPGAAGPPGAKGPPGDDGPKGN 1319
Query: 444 RGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPP- 502
GP G G+P G D G G + Q P P G PP PP
Sbjct: 1320 PGPVGFPGDPGPPGEPGPAGQD------GVGGDK-GEDGDPGQPGPPGPSGEAGPPGPPG 1372
Query: 503 ---PGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRG-MDRGG 553
P G G G G +G +G G PG G G G G RG G + G
Sbjct: 1373 KRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQG 1432
Query: 554 FGG--GRRGGPG--GPPG-PLMEQMGGRRGGRGGPG 584
G G+ G PG GPPG P ++ G +G +G PG
Sbjct: 1433 LPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPG 1468
Score = 70.5 bits (171), Expect = 4e-12
Identities = 84/264 (31%), Positives = 98/264 (37%), Gaps = 44/264 (16%)
Query: 361 YEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGG 420
YED PT+ E+ G + + S+ + G P GM L GP G
Sbjct: 401 YEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGM---LVEGPPG 457
Query: 421 PGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGG---------NVQHRAGDWQCP 469
P GP G MG G +G G G RGP G G P G + R G
Sbjct: 458 PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 517
Query: 470 NPGCGNQNFAWRTECNQCKA-----PKPEGFLPPPFPPPG-------GDRGRGGPGGMRG 517
P Q + Q + P P G P P G G+ G GP G RG
Sbjct: 518 GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 577
Query: 518 GRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGMDRGGFGG-----GRRG--GPGGP 565
+G G PG R G G RG G +G RG D G G G RG GP GP
Sbjct: 578 VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFD--GLPGLPGDKGHRGERGPQGP 635
Query: 566 PGPL----MEQMGGRRGGRGGPGK 585
PGP M G G RG PG+
Sbjct: 636 PGPPGDDGMRGEDGEIGPRGLPGE 659
Score = 67.4 bits (163), Expect = 4e-11
Identities = 106/411 (25%), Positives = 131/411 (31%), Gaps = 83/411 (20%)
Query: 154 QQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQA-----PSQYSQQSSSYGQQ 208
QQ +GQ G + G G Q P + G P +
Sbjct: 1187 QQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNG 1246
Query: 209 SSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGM 268
+ Q P S+G G G PGE + P G G +RG G G G
Sbjct: 1247 ADGPQGPPGSVGSVGGV-GEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP 1305
Query: 269 GSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQC 328
G+ G G G P G D GPP +P Q
Sbjct: 1306 GAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAG------------------------QD 1341
Query: 329 GVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSK-LKVS 387
GV G P + G P PP + + QG K K
Sbjct: 1342 GVGGDKGEDGDP-------GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1394
Query: 388 LARKKPPMNS------MRGGLPPREG-RGMPPPL--RGGPGGPG--GPGGPMGRMG--GR 434
+ PP + G P EG RG+P P+ +G PG G GP GPMG G G
Sbjct: 1395 AGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGL 1454
Query: 435 GGDRGGFPPRGPRGSRGNPS-----GGGNVQHRAGDWQCP----NPGCGNQNFAWRTECN 485
GD G +G +G+P G Q GD P +PG
Sbjct: 1455 KGDPGS------KGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDG-------- 1500
Query: 486 QCKAPKPEGFLPPPFPP-------PGGDRGRGGPGGMRGGRGGLMDRGGPG 529
P P G L PP PP P G++G GP G +G G G PG
Sbjct: 1501 --GIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1549
Score = 65.5 bits (158), Expect = 1e-10
Identities = 105/408 (25%), Positives = 131/408 (32%), Gaps = 81/408 (19%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQSSFRQDHPS 217
G+P GQQ +GQ+ G + P G P ++ G P
Sbjct: 1180 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1239
Query: 218 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGF 277
G PG S+ G +G + G G GG +G G GE G
Sbjct: 1240 GPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPP 1299
Query: 278 NKPGGPMDEGPDLDLGP---------PVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQC 328
G P +GP D GP P DP + G+ D
Sbjct: 1300 GAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDG-------- 1351
Query: 329 GVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSK-LKVS 387
GQP G P PP + + QG K K
Sbjct: 1352 -------DPGQP----------GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1394
Query: 388 LARKKPPMNSMR------GGLPPREG-RGMPPPL--RGGPGGPG--GPGGPMGRMG--GR 434
+ PP + G P EG RG+P P+ +G PG G GP GPMG G G
Sbjct: 1395 AGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGL 1454
Query: 435 GGDRGGFPPRGPRGSRGNPS-----GGGNVQHRAGDWQCP----NPGCGNQNFAWRTECN 485
GD G +G +G+P G Q GD P +PG
Sbjct: 1455 KGDPGS------KGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDG-------- 1500
Query: 486 QCKAPKPEGFLPPPFPP----PGGDRGRGGPGGMRGGRGGLMDRGGPG 529
P P G L PP PP P G +G G G G +G D G PG
Sbjct: 1501 --GIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKG---DSGLPG 1543
Score = 61.6 bits (148), Expect = 2e-09
Identities = 68/188 (36%), Positives = 76/188 (40%), Gaps = 23/188 (12%)
Query: 408 RGMPPP--LRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRG---PRGSRGNPSGGGNVQHR 462
RG P P L G PG GGPG + G GD G PRG P G G P G
Sbjct: 540 RGPPGPMGLTGRPGPVGGPGSSGAK--GESGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD 597
Query: 463 AGDWQCPNPGC-GNQNFAWRTECNQCKAPKPE-GFLPPPFPPPGGDRGRGGPGGMRGGRG 520
G PG G++ F K + E G PP PP G GMRG G
Sbjct: 598 GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP--------GDDGMRGEDG 649
Query: 521 GLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRG--GPGGPPGPLMEQMGGR 576
+ RG PG G G RG G G GM G +G GP G PGP +Q G
Sbjct: 650 EIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQ--GN 707
Query: 577 RGGRGGPG 584
G +G PG
Sbjct: 708 PGPQGLPG 715
Score = 37.0 bits (84), Expect = 0.052
Identities = 66/246 (26%), Positives = 78/246 (31%), Gaps = 34/246 (13%)
Query: 216 PSSMGVYGQES-GGFSGPGENRSMSGPDNRGRGRGG----FDRGGMSRGGRGGGRGGMGS 270
P G GQ+ GG G + GP G RG G G +G G+
Sbjct: 1332 PGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGA 1391
Query: 271 AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGV 330
GE G PG GP G P + QGL + D G+
Sbjct: 1392 KGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGL 1451
Query: 331 VKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSL-A 389
+ G E G P + PP QG K L
Sbjct: 1452 PGLKGDPGSK-------GEKGHP---GLIGLIGPPGE------------QGEKGDRGLPG 1489
Query: 390 RKKPPMNSMRGGLP-PREGRGMP-PPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPR 447
+ P GG+P P G P PP GP GP G G G G +G G P GP
Sbjct: 1490 TQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGD--SGLP--GPP 1545
Query: 448 GSRGNP 453
GS G P
Sbjct: 1546 GSPGPP 1551
Score = 33.1 bits (74), Expect = 0.75
Identities = 50/224 (22%), Positives = 74/224 (33%), Gaps = 31/224 (13%)
Query: 114 AQSAYGTQPAYPAYGQQPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQ 173
A A G Q A G+ A P P + G P G+Q G
Sbjct: 1379 AAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQG-PAGKPGPEGLRGIPGPVGEQGLPGAA 1437
Query: 174 SSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPG 233
G P P G S+ G++ HP +G+ G G G
Sbjct: 1438 GQDGPPGPMGPPGLPGLKGDPGSK--------GEKG-----HPGLIGLIGPP--GEQGEK 1482
Query: 234 ENRSMSGPDNR--GRGRGGFDRGGMSRGGRG-----------GGRGGMGSAGERGGFNKP 280
+R + G +G GG G G G +G G AG++G P
Sbjct: 1483 GDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLP 1542
Query: 281 GGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADF 324
G P GP ++ P+ P S + + +G+ D++ D+
Sbjct: 1543 GPPGSPGPPGEVIQPL-PILSSKKTRRHTEGMQADAD-DNILDY 1584
>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
sapiens]
Length = 1767
Score = 89.7 bits (221), Expect = 7e-18
Identities = 130/482 (26%), Positives = 162/482 (33%), Gaps = 118/482 (24%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQ----------APSQYSQQSSSYGQQ 208
G+P GQQ + G Q G Q P P + G + P + + G++
Sbjct: 646 GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK 705
Query: 209 SSFRQD-------HPSSMGVYGQ-----------ESGGFSGPGENRSMSGPDNRG----- 245
+ +P GV G E G PG M +RG
Sbjct: 706 GALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQI 765
Query: 246 --RGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPG---GPMDEGPDLDLGPPVDPDE 300
RG G G R G G G G AGE+G PG P +GP G P P
Sbjct: 766 GPRGEDG-PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGA 824
Query: 301 DSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVS 360
+ + A V G + G TG P TGKP T
Sbjct: 825 NGEKGARGVAG---------------KPGPRGQRGPTG-PRGSRGARGPTGKPGPKGTSG 868
Query: 361 YEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK-PPMNSMRGGLPPREGRGMPPPLRG--G 417
+ PP + QG + V K PP + GLP G+ +G G
Sbjct: 869 GDGPPGPPGE------RGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 922
Query: 418 PGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGN 475
P GPGG GP G G G G+RG P GP G +G P G + GD
Sbjct: 923 PPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK-EGAKGD---------- 971
Query: 476 QNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGG 535
P P G G+ GP G+RG G +RG PG G
Sbjct: 972 -------------------------PGPQGISGKDGPAGLRGFPG---ERGLPGAQGAPG 1003
Query: 536 RGGDRG-----------GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQ-MGGRRGGRGGP 583
G G G RG G G G R GP GPPGP E+ G +G +G
Sbjct: 1004 LKGGEGPQGPPGPVGSPGERGSAGT-AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPA 1062
Query: 584 GK 585
G+
Sbjct: 1063 GR 1064
Score = 85.1 bits (209), Expect = 2e-16
Identities = 123/451 (27%), Positives = 159/451 (35%), Gaps = 44/451 (9%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGS--YSQAPSQYSQQSSSYGQQSSFRQDHP 216
G+ G+ G G Q PT G + P +Q + P
Sbjct: 913 GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP 972
Query: 217 SSMGVYGQES-GGFSG-PGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGER 274
G+ G++ G G PGE R + G +GG G G G G GSAG
Sbjct: 973 GPQGISGKDGPAGLRGFPGE-RGLPGAQGAPGLKGG--EGPQGPPGPVGSPGERGSAGTA 1029
Query: 275 GGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMN 334
G PG P +GP G P E G+ V L A G
Sbjct: 1030 GPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1089
Query: 335 KRTGQP-MIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKP 393
G+P DK P G + P + DG+ G + + + +K
Sbjct: 1090 GEIGEPGQKGSKGDKGENGPPGPPGLQ---GPVGAPGIAGGDGEP--GPRGQQGMFGQKG 1144
Query: 394 PMNSMRGGLPPR----EGRGMPPPLRG-----GPGGPGGPGGPMGRMGGRGGDRGGFPPR 444
+ PP +G PP +G GP GP GP GP G G G D P+
Sbjct: 1145 DEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGAD----GPQ 1200
Query: 445 GPRGSRGNPSGGGNVQHRAGDWQCPNP----GCGNQNFAWRTECNQCKAPKPEGFLPPPF 500
GP GS G+ G G + G+ P P G G + E + P G PP
Sbjct: 1201 GPPGSVGSVGGVGE-KGEPGEAGNPGPPGEAGVGGP----KGERGEKGEAGPPGAAGPPG 1255
Query: 501 P--PPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGR 558
PPG D +G PG + G G G PG + G GGD+G G G G
Sbjct: 1256 AKGPPGDDGPKGNPGPV-GFPGDPGPPGEPGPAGQDGVGGDKG--EDGDPGQPGPPGPSG 1312
Query: 559 RGGPGGPPG----PLMEQMGGRRGGRGGPGK 585
GP GPPG P GR+G +G G+
Sbjct: 1313 EAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1343
Score = 82.8 bits (203), Expect = 8e-16
Identities = 144/478 (30%), Positives = 185/478 (38%), Gaps = 74/478 (15%)
Query: 149 QSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQA-PSQYSQQSSSYGQ 207
+ S ++ G P G G + GQ P G +A P+ S G+
Sbjct: 735 KGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGE 794
Query: 208 QSSFR----QDHPSSMGVYGQESGGFSG-PGEN-----RSMSG-PDNRGRGRGGFDRGGM 256
+ +P G G S GF G PG N R ++G P RG+ RG
Sbjct: 795 KGKLGVPGLPGYPGRQGPKG--STGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRG-- 850
Query: 257 SRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSV 316
SRG RG G G G GG PG P + GP GP P +G
Sbjct: 851 SRGARGP-TGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP---------KGPPGPP 900
Query: 317 TLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKE--TGK--PKGDATVSYEDPPTAKAAVE 372
D L Q G +TG P + + TG+ P G+ P + +
Sbjct: 901 GKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLP 960
Query: 373 WFDGKD-FQGSKLKVSLARKKPPMNSMRG-----GLPPREGRGMPPPLRGGPGGPGGPGG 426
GK+ +G ++ K P +RG GLP +G P L+GG G P GP G
Sbjct: 961 GAAGKEGAKGDPGPQGISGKDGPAG-LRGFPGERGLPGAQGA---PGLKGGEG-PQGPPG 1015
Query: 427 PMGRMGGRG--GDRG--GFPPR-GPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWR 481
P+G G RG G G G P R GP+G G P+G G Q P G Q
Sbjct: 1016 PVGSPGERGSAGTAGPIGLPGRPGPQGPPG-PAGEKGAPGEKGP-QGPAGRDGVQG---- 1069
Query: 482 TECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRG--GPGGM-----FRG 534
P P G P P GD+G G G +G +G + G GP G+ G
Sbjct: 1070 ----PVGLPGPAG--PAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPG 1123
Query: 535 GRGGD-RGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEH 591
GGD G RG +GM G RG P GPPGP+ G +G G PG +KGE+
Sbjct: 1124 IAGGDGEPGPRGQQGMFGQKGDEGARGFP-GPPGPI-----GLQGLPGPPG--EKGEN 1173
Score = 80.5 bits (197), Expect = 4e-15
Identities = 113/373 (30%), Positives = 140/373 (37%), Gaps = 105/373 (28%)
Query: 254 GGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLN 313
G M GR G GG GS+G +G + G P +GP GPP
Sbjct: 493 GPMGLTGRPGPVGGPGSSGAKG---ESGDPGPQGPRGVQGPPGP---------------- 533
Query: 314 DSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEW 373
TG+P + G+P D P AK
Sbjct: 534 -----------------------TGKP-------GKRGRPGADGGRGMPGEPGAKGD-RG 562
Query: 374 FDG-------KDFQGSKLKVSLARKKPPMNSMRG--------GLPPREG-RGMPPPLRGG 417
FDG K +G + P + MRG GLP G RG+ P RG
Sbjct: 563 FDGLPGLPGDKGHRGERGPQG-PPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGP-RGT 620
Query: 418 PGGPGGPG--------GPMGRMGGRG-----GDRGGFPPRGPRGSRG--NPSGGGNVQHR 462
PG PG PG GP G MG +G G +G P+G G +G P G Q +
Sbjct: 621 PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 680
Query: 463 AG-------DWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGM 515
G D +PG Q+ E P P+G P +P P G +G G G+
Sbjct: 681 PGLAGLPGADGPPGHPGKEGQS----GEKGALGPPGPQG--PIGYPGPRGVKGADGVRGL 734
Query: 516 RGGRGGLMDRGGPGGMFRGGRG--GDRG--GFRGGRGMDRGGFGGGRRGGPGGPPGPLME 571
+G +G + G PG F+G G GDRG G G RG D G G R GP G PGP
Sbjct: 735 KGSKGEKGEDGFPG--FKGDMGLKGDRGEVGQIGPRGED-GPEGPKGRAGPTGDPGP--S 789
Query: 572 QMGGRRGGRGGPG 584
G +G G PG
Sbjct: 790 GQAGEKGKLGVPG 802
Score = 78.6 bits (192), Expect = 2e-14
Identities = 131/503 (26%), Positives = 171/503 (33%), Gaps = 77/503 (15%)
Query: 130 QPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTG 189
+P S + S D + G P G+ G+ + G + P G
Sbjct: 500 RPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKG 559
Query: 190 S--YSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESG----GFSGPGENRSMSGPDN 243
+ P + + P G+ G++ G G R + GP
Sbjct: 560 DRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGP-- 617
Query: 244 RGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSD 303
RG G G G +G MG GE G + G P +G GP P E
Sbjct: 618 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 677
Query: 304 NSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYED 363
+ GL AD G + GQ L G P + Y
Sbjct: 678 QGKPGLAGLPG-------AD-----GPPGHPGKEGQSGEKGAL----GPPGPQGPIGYPG 721
Query: 364 PPTAKAAVEWFDG-KDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPG 422
P K A DG + +GSK + + + +G + + RG + GP G
Sbjct: 722 PRGVKGA----DGVRGLKGSKGE----KGEDGFPGFKGDMGLKGDRGEVGQI--GPRGED 771
Query: 423 GPGGPMGRMG--------GRGGDRG--------GFPPR-GPRGSRGNPSGGGNVQHRAGD 465
GP GP GR G G+ G++G G+P R GP+GS G P G +
Sbjct: 772 GPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGAR 831
Query: 466 WQCPNPGCGNQN-----FAWRTECNQCKAPKPEGFLPPPFPP-PGGDRGRGGPGGMRGGR 519
PG Q R P P+G PP P G+RG GP G G
Sbjct: 832 GVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFP 891
Query: 520 GGLMDRGGPGGMFRGGRGGDRG--GFRGGRG-MDRGGFGG-----------GRRGGPGGP 565
G G PG G G RG GF+G G GG G G RG P GP
Sbjct: 892 GPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHP-GP 950
Query: 566 PGPLMEQ----MGGRRGGRGGPG 584
PGP EQ G+ G +G PG
Sbjct: 951 PGPPGEQGLPGAAGKEGAKGDPG 973
Score = 78.6 bits (192), Expect = 2e-14
Identities = 120/404 (29%), Positives = 151/404 (37%), Gaps = 84/404 (20%)
Query: 216 PSSMGVYGQESGGFSGPGENRSMSGPDNRG-----RGRGGFDRG-GM-----SRGGRG-- 262
P S G G+ G GP R + GP RGR G D G GM ++G RG
Sbjct: 507 PGSSGAKGES--GDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFD 564
Query: 263 ---GGRGGMGSAGERGGFNKPGGPMDE---GPDLDLGPPVDPDEDSDNSAIYVQGLNDSV 316
G G G GERG PG P D+ G D ++GP P E + +G +
Sbjct: 565 GLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGA- 623
Query: 317 TLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDG 376
GQP + +D G PKG+ E P +
Sbjct: 624 --------------------PGQPGM-AGVDGPPG-PKGNMGPQGEPGPPGQ-------- 653
Query: 377 KDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGG 436
QG+ L + P+ G P +G P L G PG G PG P G+ G
Sbjct: 654 ---QGNPGPQGLPGPQGPI-----GPPGEKGPQGKPGLAGLPGADGPPGHP--GKEGQSG 703
Query: 437 DRGGFPPRGPRGSRGNP-----SGGGNVQHRAGD----WQCPNPGC-GNQNFAW-RTECN 485
++G P GP+G G P G V+ G + PG G+ R E
Sbjct: 704 EKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG 763
Query: 486 QCKAPKPEGFLPPPFPPPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-- 541
Q +G P P G G G GP G G +G L G PG R G G G
Sbjct: 764 QIGPRGEDG----PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 819
Query: 542 GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 585
GF G G ++G G + GP G GP + G RG RG GK
Sbjct: 820 GFPGANG-EKGARGVAGKPGPRGQRGPTGPR--GSRGARGPTGK 860
Score = 77.0 bits (188), Expect = 5e-14
Identities = 131/464 (28%), Positives = 171/464 (36%), Gaps = 111/464 (23%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G+ + G++ G G Q P P G P+ + G+ P
Sbjct: 1048 GEKGAPGEKGPQGPAGRDGVQGPVGLPGPAG-----PAGSPGEDGDKGEIGE-----PGQ 1097
Query: 219 MGVYGQ--ESG-----GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSA 271
G G E+G G GP ++G D RG +G + G G RG G
Sbjct: 1098 KGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRG--QQGMFGQKGDEGARGFPGPP 1155
Query: 272 GERGGFNKPGGPMDEGPDLDLGPPVDPDE------DSDNSAIYVQGLNDSVTLDDLADFF 325
G G PG P ++G + D+GP P N A QG SV
Sbjct: 1156 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV--------- 1206
Query: 326 KQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLK 385
G V G+P E G P P +A V G+ +G K +
Sbjct: 1207 ---GSVGGVGEKGEP-------GEAGNPG----------PPGEAGVGGPKGE--RGEKGE 1244
Query: 386 VSLARKKPPMNSMRGGLPPREG-RGMPPPLRGGPGGPGGPG--GPMGRMGGRGGDRG--- 439
P + G P +G +G P P+ G PG PG PG GP G+ G GGD+G
Sbjct: 1245 AGPPGAAGPPGAK--GPPGDDGPKGNPGPV-GFPGDPGPPGEPGPAGQ-DGVGGDKGEDG 1300
Query: 440 --GFP----------PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQC 487
G P P GP G RG P G + R G+ + +
Sbjct: 1301 DPGQPGPPGPSGEAGPPGPPGKRG-PPGAAGAEGRQGE---------------KGAKGEA 1344
Query: 488 KAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRG 545
A P G P P G G+ GP G+RG G + ++G PG + G G G G G
Sbjct: 1345 GAEGPPGKTGPVGPQ--GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPG 1402
Query: 546 GRGMDRGGFGGGRRGGPG-----GPPGPLMEQMGGRRGGRGGPG 584
+G D G G +G PG GPPG EQ G +G RG PG
Sbjct: 1403 LKG-DPG--SKGEKGHPGLIGLIGPPG---EQ--GEKGDRGLPG 1438
Score = 70.9 bits (172), Expect = 3e-12
Identities = 122/456 (26%), Positives = 154/456 (33%), Gaps = 62/456 (13%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G P + G G + G P P + GS A
Sbjct: 994 GLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTA----------------------GP 1031
Query: 219 MGVYGQESGGFSGPGENRSMSGPDNRG-RGRGGFD--RGGMSRGGRGGGRGGMGSAGERG 275
+G+ G+ G PG P +G +G G D +G + G G G G G++G
Sbjct: 1032 IGLPGRP-GPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKG 1090
Query: 276 GFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNK 335
+PG +G + GPP P A + G + F Q G
Sbjct: 1091 EIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARG 1150
Query: 336 RTGQPMIHIYLDKETGKP-----KGDATVSYEDPPTAKAAVEWFDGKDF-QGSKLKVS-- 387
G P I L G P GD P + +G D QG V
Sbjct: 1151 FPGPPG-PIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSV 1209
Query: 388 --LARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG--GDRGGFPP 443
+ K P + G P G G P RG G GP G G G +G GD G
Sbjct: 1210 GGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKG-EAGPPGAAGPPGAKGPPGDDGPKGN 1268
Query: 444 RGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPP- 502
GP G G+P G D G G + Q P P G PP PP
Sbjct: 1269 PGPVGFPGDPGPPGEPGPAGQD------GVGGDK-GEDGDPGQPGPPGPSGEAGPPGPPG 1321
Query: 503 ---PGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRG-MDRGG 553
P G G G G +G +G G PG G G G G RG G + G
Sbjct: 1322 KRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQG 1381
Query: 554 FGG--GRRGGPG--GPPG-PLMEQMGGRRGGRGGPG 584
G G+ G PG GPPG P ++ G +G +G PG
Sbjct: 1382 LPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPG 1417
Score = 70.5 bits (171), Expect = 4e-12
Identities = 84/264 (31%), Positives = 98/264 (37%), Gaps = 44/264 (16%)
Query: 361 YEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGG 420
YED PT+ E+ G + + S+ + G P GM L GP G
Sbjct: 350 YEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGM---LVEGPPG 406
Query: 421 PGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGG---------NVQHRAGDWQCP 469
P GP G MG G +G G G RGP G G P G + R G
Sbjct: 407 PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 466
Query: 470 NPGCGNQNFAWRTECNQCKA-----PKPEGFLPPPFPPPG-------GDRGRGGPGGMRG 517
P Q + Q + P P G P P G G+ G GP G RG
Sbjct: 467 GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 526
Query: 518 GRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGMDRGGFGG-----GRRG--GPGGP 565
+G G PG R G G RG G +G RG D G G G RG GP GP
Sbjct: 527 VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFD--GLPGLPGDKGHRGERGPQGP 584
Query: 566 PGPL----MEQMGGRRGGRGGPGK 585
PGP M G G RG PG+
Sbjct: 585 PGPPGDDGMRGEDGEIGPRGLPGE 608
Score = 67.4 bits (163), Expect = 4e-11
Identities = 106/411 (25%), Positives = 131/411 (31%), Gaps = 83/411 (20%)
Query: 154 QQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQA-----PSQYSQQSSSYGQQ 208
QQ +GQ G + G G Q P + G P +
Sbjct: 1136 QQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNG 1195
Query: 209 SSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGM 268
+ Q P S+G G G PGE + P G G +RG G G G
Sbjct: 1196 ADGPQGPPGSVGSVGGV-GEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP 1254
Query: 269 GSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQC 328
G+ G G G P G D GPP +P Q
Sbjct: 1255 GAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAG------------------------QD 1290
Query: 329 GVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSK-LKVS 387
GV G P + G P PP + + QG K K
Sbjct: 1291 GVGGDKGEDGDP-------GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1343
Query: 388 LARKKPPMNS------MRGGLPPREG-RGMPPPL--RGGPGGPG--GPGGPMGRMG--GR 434
+ PP + G P EG RG+P P+ +G PG G GP GPMG G G
Sbjct: 1344 AGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGL 1403
Query: 435 GGDRGGFPPRGPRGSRGNPS-----GGGNVQHRAGDWQCP----NPGCGNQNFAWRTECN 485
GD G +G +G+P G Q GD P +PG
Sbjct: 1404 KGDPGS------KGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDG-------- 1449
Query: 486 QCKAPKPEGFLPPPFPP-------PGGDRGRGGPGGMRGGRGGLMDRGGPG 529
P P G L PP PP P G++G GP G +G G G PG
Sbjct: 1450 --GIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1498
Score = 65.5 bits (158), Expect = 1e-10
Identities = 105/408 (25%), Positives = 131/408 (32%), Gaps = 81/408 (19%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQSSFRQDHPS 217
G+P GQQ +GQ+ G + P G P ++ G P
Sbjct: 1129 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1188
Query: 218 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGF 277
G PG S+ G +G + G G GG +G G GE G
Sbjct: 1189 GPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPP 1248
Query: 278 NKPGGPMDEGPDLDLGP---------PVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQC 328
G P +GP D GP P DP + G+ D
Sbjct: 1249 GAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDG-------- 1300
Query: 329 GVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSK-LKVS 387
GQP G P PP + + QG K K
Sbjct: 1301 -------DPGQP----------GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1343
Query: 388 LARKKPPMNSMR------GGLPPREG-RGMPPPL--RGGPGGPG--GPGGPMGRMG--GR 434
+ PP + G P EG RG+P P+ +G PG G GP GPMG G G
Sbjct: 1344 AGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGL 1403
Query: 435 GGDRGGFPPRGPRGSRGNPS-----GGGNVQHRAGDWQCP----NPGCGNQNFAWRTECN 485
GD G +G +G+P G Q GD P +PG
Sbjct: 1404 KGDPGS------KGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDG-------- 1449
Query: 486 QCKAPKPEGFLPPPFPP----PGGDRGRGGPGGMRGGRGGLMDRGGPG 529
P P G L PP PP P G +G G G G +G D G PG
Sbjct: 1450 --GIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKG---DSGLPG 1492
Score = 61.6 bits (148), Expect = 2e-09
Identities = 68/188 (36%), Positives = 76/188 (40%), Gaps = 23/188 (12%)
Query: 408 RGMPPP--LRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRG---PRGSRGNPSGGGNVQHR 462
RG P P L G PG GGPG + G GD G PRG P G G P G
Sbjct: 489 RGPPGPMGLTGRPGPVGGPGSSGAK--GESGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD 546
Query: 463 AGDWQCPNPGC-GNQNFAWRTECNQCKAPKPE-GFLPPPFPPPGGDRGRGGPGGMRGGRG 520
G PG G++ F K + E G PP PP G GMRG G
Sbjct: 547 GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP--------GDDGMRGEDG 598
Query: 521 GLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRG--GPGGPPGPLMEQMGGR 576
+ RG PG G G RG G G GM G +G GP G PGP +Q G
Sbjct: 599 EIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQ--GN 656
Query: 577 RGGRGGPG 584
G +G PG
Sbjct: 657 PGPQGLPG 664
Score = 37.0 bits (84), Expect = 0.052
Identities = 66/246 (26%), Positives = 78/246 (31%), Gaps = 34/246 (13%)
Query: 216 PSSMGVYGQES-GGFSGPGENRSMSGPDNRGRGRGG----FDRGGMSRGGRGGGRGGMGS 270
P G GQ+ GG G + GP G RG G G +G G+
Sbjct: 1281 PGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGA 1340
Query: 271 AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGV 330
GE G PG GP G P + QGL + D G+
Sbjct: 1341 KGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGL 1400
Query: 331 VKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSL-A 389
+ G E G P + PP QG K L
Sbjct: 1401 PGLKGDPGSK-------GEKGHP---GLIGLIGPPGE------------QGEKGDRGLPG 1438
Query: 390 RKKPPMNSMRGGLP-PREGRGMP-PPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPR 447
+ P GG+P P G P PP GP GP G G G G +G G P GP
Sbjct: 1439 TQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGD--SGLP--GPP 1494
Query: 448 GSRGNP 453
GS G P
Sbjct: 1495 GSPGPP 1500
Score = 33.1 bits (74), Expect = 0.75
Identities = 50/224 (22%), Positives = 74/224 (33%), Gaps = 31/224 (13%)
Query: 114 AQSAYGTQPAYPAYGQQPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQ 173
A A G Q A G+ A P P + G P G+Q G
Sbjct: 1328 AAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQG-PAGKPGPEGLRGIPGPVGEQGLPGAA 1386
Query: 174 SSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPG 233
G P P G S+ G++ HP +G+ G G G
Sbjct: 1387 GQDGPPGPMGPPGLPGLKGDPGSK--------GEKG-----HPGLIGLIGPP--GEQGEK 1431
Query: 234 ENRSMSGPDNR--GRGRGGFDRGGMSRGGRG-----------GGRGGMGSAGERGGFNKP 280
+R + G +G GG G G G +G G AG++G P
Sbjct: 1432 GDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLP 1491
Query: 281 GGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADF 324
G P GP ++ P+ P S + + +G+ D++ D+
Sbjct: 1492 GPPGSPGPPGEVIQPL-PILSSKKTRRHTEGMQADAD-DNILDY 1533
>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
sapiens]
Length = 1806
Score = 89.7 bits (221), Expect = 7e-18
Identities = 130/482 (26%), Positives = 162/482 (33%), Gaps = 118/482 (24%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQ----------APSQYSQQSSSYGQQ 208
G+P GQQ + G Q G Q P P + G + P + + G++
Sbjct: 685 GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEK 744
Query: 209 SSFRQD-------HPSSMGVYGQ-----------ESGGFSGPGENRSMSGPDNRG----- 245
+ +P GV G E G PG M +RG
Sbjct: 745 GALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQI 804
Query: 246 --RGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPG---GPMDEGPDLDLGPPVDPDE 300
RG G G R G G G G AGE+G PG P +GP G P P
Sbjct: 805 GPRGEDG-PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGA 863
Query: 301 DSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVS 360
+ + A V G + G TG P TGKP T
Sbjct: 864 NGEKGARGVAG---------------KPGPRGQRGPTG-PRGSRGARGPTGKPGPKGTSG 907
Query: 361 YEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK-PPMNSMRGGLPPREGRGMPPPLRG--G 417
+ PP + QG + V K PP + GLP G+ +G G
Sbjct: 908 GDGPPGPPGE------RGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTG 961
Query: 418 PGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGN 475
P GPGG GP G G G G+RG P GP G +G P G + GD
Sbjct: 962 PPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGK-EGAKGD---------- 1010
Query: 476 QNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGG 535
P P G G+ GP G+RG G +RG PG G
Sbjct: 1011 -------------------------PGPQGISGKDGPAGLRGFPG---ERGLPGAQGAPG 1042
Query: 536 RGGDRG-----------GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQ-MGGRRGGRGGP 583
G G G RG G G G R GP GPPGP E+ G +G +G
Sbjct: 1043 LKGGEGPQGPPGPVGSPGERGSAGT-AGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPA 1101
Query: 584 GK 585
G+
Sbjct: 1102 GR 1103
Score = 85.1 bits (209), Expect = 2e-16
Identities = 123/451 (27%), Positives = 159/451 (35%), Gaps = 44/451 (9%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGS--YSQAPSQYSQQSSSYGQQSSFRQDHP 216
G+ G+ G G Q PT G + P +Q + P
Sbjct: 952 GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP 1011
Query: 217 SSMGVYGQES-GGFSG-PGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGER 274
G+ G++ G G PGE R + G +GG G G G G GSAG
Sbjct: 1012 GPQGISGKDGPAGLRGFPGE-RGLPGAQGAPGLKGG--EGPQGPPGPVGSPGERGSAGTA 1068
Query: 275 GGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMN 334
G PG P +GP G P E G+ V L A G
Sbjct: 1069 GPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDK 1128
Query: 335 KRTGQP-MIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKP 393
G+P DK P G + P + DG+ G + + + +K
Sbjct: 1129 GEIGEPGQKGSKGDKGENGPPGPPGLQ---GPVGAPGIAGGDGEP--GPRGQQGMFGQKG 1183
Query: 394 PMNSMRGGLPPR----EGRGMPPPLRG-----GPGGPGGPGGPMGRMGGRGGDRGGFPPR 444
+ PP +G PP +G GP GP GP GP G G G D P+
Sbjct: 1184 DEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGAD----GPQ 1239
Query: 445 GPRGSRGNPSGGGNVQHRAGDWQCPNP----GCGNQNFAWRTECNQCKAPKPEGFLPPPF 500
GP GS G+ G G + G+ P P G G + E + P G PP
Sbjct: 1240 GPPGSVGSVGGVGE-KGEPGEAGNPGPPGEAGVGGP----KGERGEKGEAGPPGAAGPPG 1294
Query: 501 P--PPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGR 558
PPG D +G PG + G G G PG + G GGD+G G G G
Sbjct: 1295 AKGPPGDDGPKGNPGPV-GFPGDPGPPGEPGPAGQDGVGGDKG--EDGDPGQPGPPGPSG 1351
Query: 559 RGGPGGPPG----PLMEQMGGRRGGRGGPGK 585
GP GPPG P GR+G +G G+
Sbjct: 1352 EAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1382
Score = 82.8 bits (203), Expect = 8e-16
Identities = 144/478 (30%), Positives = 185/478 (38%), Gaps = 74/478 (15%)
Query: 149 QSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQA-PSQYSQQSSSYGQ 207
+ S ++ G P G G + GQ P G +A P+ S G+
Sbjct: 774 KGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGE 833
Query: 208 QSSFR----QDHPSSMGVYGQESGGFSG-PGEN-----RSMSG-PDNRGRGRGGFDRGGM 256
+ +P G G S GF G PG N R ++G P RG+ RG
Sbjct: 834 KGKLGVPGLPGYPGRQGPKG--STGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRG-- 889
Query: 257 SRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSV 316
SRG RG G G G GG PG P + GP GP P +G
Sbjct: 890 SRGARGP-TGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP---------KGPPGPP 939
Query: 317 TLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKE--TGK--PKGDATVSYEDPPTAKAAVE 372
D L Q G +TG P + + TG+ P G+ P + +
Sbjct: 940 GKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLP 999
Query: 373 WFDGKD-FQGSKLKVSLARKKPPMNSMRG-----GLPPREGRGMPPPLRGGPGGPGGPGG 426
GK+ +G ++ K P +RG GLP +G P L+GG G P GP G
Sbjct: 1000 GAAGKEGAKGDPGPQGISGKDGPAG-LRGFPGERGLPGAQGA---PGLKGGEG-PQGPPG 1054
Query: 427 PMGRMGGRG--GDRG--GFPPR-GPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWR 481
P+G G RG G G G P R GP+G G P+G G Q P G Q
Sbjct: 1055 PVGSPGERGSAGTAGPIGLPGRPGPQGPPG-PAGEKGAPGEKGP-QGPAGRDGVQG---- 1108
Query: 482 TECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRG--GPGGM-----FRG 534
P P G P P GD+G G G +G +G + G GP G+ G
Sbjct: 1109 ----PVGLPGPAG--PAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPG 1162
Query: 535 GRGGD-RGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEH 591
GGD G RG +GM G RG P GPPGP+ G +G G PG +KGE+
Sbjct: 1163 IAGGDGEPGPRGQQGMFGQKGDEGARGFP-GPPGPI-----GLQGLPGPPG--EKGEN 1212
Score = 80.5 bits (197), Expect = 4e-15
Identities = 113/373 (30%), Positives = 140/373 (37%), Gaps = 105/373 (28%)
Query: 254 GGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLN 313
G M GR G GG GS+G +G + G P +GP GPP
Sbjct: 532 GPMGLTGRPGPVGGPGSSGAKG---ESGDPGPQGPRGVQGPPGP---------------- 572
Query: 314 DSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEW 373
TG+P + G+P D P AK
Sbjct: 573 -----------------------TGKP-------GKRGRPGADGGRGMPGEPGAKGD-RG 601
Query: 374 FDG-------KDFQGSKLKVSLARKKPPMNSMRG--------GLPPREG-RGMPPPLRGG 417
FDG K +G + P + MRG GLP G RG+ P RG
Sbjct: 602 FDGLPGLPGDKGHRGERGPQG-PPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGP-RGT 659
Query: 418 PGGPGGPG--------GPMGRMGGRG-----GDRGGFPPRGPRGSRG--NPSGGGNVQHR 462
PG PG PG GP G MG +G G +G P+G G +G P G Q +
Sbjct: 660 PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 719
Query: 463 AG-------DWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGM 515
G D +PG Q+ E P P+G P +P P G +G G G+
Sbjct: 720 PGLAGLPGADGPPGHPGKEGQS----GEKGALGPPGPQG--PIGYPGPRGVKGADGVRGL 773
Query: 516 RGGRGGLMDRGGPGGMFRGGRG--GDRG--GFRGGRGMDRGGFGGGRRGGPGGPPGPLME 571
+G +G + G PG F+G G GDRG G G RG D G G R GP G PGP
Sbjct: 774 KGSKGEKGEDGFPG--FKGDMGLKGDRGEVGQIGPRGED-GPEGPKGRAGPTGDPGP--S 828
Query: 572 QMGGRRGGRGGPG 584
G +G G PG
Sbjct: 829 GQAGEKGKLGVPG 841
Score = 78.6 bits (192), Expect = 2e-14
Identities = 131/503 (26%), Positives = 171/503 (33%), Gaps = 77/503 (15%)
Query: 130 QPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTG 189
+P S + S D + G P G+ G+ + G + P G
Sbjct: 539 RPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKG 598
Query: 190 S--YSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESG----GFSGPGENRSMSGPDN 243
+ P + + P G+ G++ G G R + GP
Sbjct: 599 DRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGP-- 656
Query: 244 RGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSD 303
RG G G G +G MG GE G + G P +G GP P E
Sbjct: 657 RGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGP 716
Query: 304 NSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYED 363
+ GL AD G + GQ L G P + Y
Sbjct: 717 QGKPGLAGLPG-------AD-----GPPGHPGKEGQSGEKGAL----GPPGPQGPIGYPG 760
Query: 364 PPTAKAAVEWFDG-KDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPG 422
P K A DG + +GSK + + + +G + + RG + GP G
Sbjct: 761 PRGVKGA----DGVRGLKGSKGE----KGEDGFPGFKGDMGLKGDRGEVGQI--GPRGED 810
Query: 423 GPGGPMGRMG--------GRGGDRG--------GFPPR-GPRGSRGNPSGGGNVQHRAGD 465
GP GP GR G G+ G++G G+P R GP+GS G P G +
Sbjct: 811 GPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGAR 870
Query: 466 WQCPNPGCGNQN-----FAWRTECNQCKAPKPEGFLPPPFPP-PGGDRGRGGPGGMRGGR 519
PG Q R P P+G PP P G+RG GP G G
Sbjct: 871 GVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFP 930
Query: 520 GGLMDRGGPGGMFRGGRGGDRG--GFRGGRG-MDRGGFGG-----------GRRGGPGGP 565
G G PG G G RG GF+G G GG G G RG P GP
Sbjct: 931 GPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHP-GP 989
Query: 566 PGPLMEQ----MGGRRGGRGGPG 584
PGP EQ G+ G +G PG
Sbjct: 990 PGPPGEQGLPGAAGKEGAKGDPG 1012
Score = 78.6 bits (192), Expect = 2e-14
Identities = 120/404 (29%), Positives = 151/404 (37%), Gaps = 84/404 (20%)
Query: 216 PSSMGVYGQESGGFSGPGENRSMSGPDNRG-----RGRGGFDRG-GM-----SRGGRG-- 262
P S G G+ G GP R + GP RGR G D G GM ++G RG
Sbjct: 546 PGSSGAKGES--GDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFD 603
Query: 263 ---GGRGGMGSAGERGGFNKPGGPMDE---GPDLDLGPPVDPDEDSDNSAIYVQGLNDSV 316
G G G GERG PG P D+ G D ++GP P E + +G +
Sbjct: 604 GLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGA- 662
Query: 317 TLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDG 376
GQP + +D G PKG+ E P +
Sbjct: 663 --------------------PGQPGM-AGVDGPPG-PKGNMGPQGEPGPPGQ-------- 692
Query: 377 KDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGG 436
QG+ L + P+ G P +G P L G PG G PG P G+ G
Sbjct: 693 ---QGNPGPQGLPGPQGPI-----GPPGEKGPQGKPGLAGLPGADGPPGHP--GKEGQSG 742
Query: 437 DRGGFPPRGPRGSRGNP-----SGGGNVQHRAGD----WQCPNPGC-GNQNFAW-RTECN 485
++G P GP+G G P G V+ G + PG G+ R E
Sbjct: 743 EKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVG 802
Query: 486 QCKAPKPEGFLPPPFPPPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-- 541
Q +G P P G G G GP G G +G L G PG R G G G
Sbjct: 803 QIGPRGEDG----PEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP 858
Query: 542 GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 585
GF G G ++G G + GP G GP + G RG RG GK
Sbjct: 859 GFPGANG-EKGARGVAGKPGPRGQRGPTGPR--GSRGARGPTGK 899
Score = 77.0 bits (188), Expect = 5e-14
Identities = 131/464 (28%), Positives = 171/464 (36%), Gaps = 111/464 (23%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G+ + G++ G G Q P P G P+ + G+ P
Sbjct: 1087 GEKGAPGEKGPQGPAGRDGVQGPVGLPGPAG-----PAGSPGEDGDKGEIGE-----PGQ 1136
Query: 219 MGVYGQ--ESG-----GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSA 271
G G E+G G GP ++G D RG +G + G G RG G
Sbjct: 1137 KGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRG--QQGMFGQKGDEGARGFPGPP 1194
Query: 272 GERGGFNKPGGPMDEGPDLDLGPPVDPDE------DSDNSAIYVQGLNDSVTLDDLADFF 325
G G PG P ++G + D+GP P N A QG SV
Sbjct: 1195 GPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSV--------- 1245
Query: 326 KQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLK 385
G V G+P E G P P +A V G+ +G K +
Sbjct: 1246 ---GSVGGVGEKGEP-------GEAGNPG----------PPGEAGVGGPKGE--RGEKGE 1283
Query: 386 VSLARKKPPMNSMRGGLPPREG-RGMPPPLRGGPGGPGGPG--GPMGRMGGRGGDRG--- 439
P + G P +G +G P P+ G PG PG PG GP G+ G GGD+G
Sbjct: 1284 AGPPGAAGPPGAK--GPPGDDGPKGNPGPV-GFPGDPGPPGEPGPAGQ-DGVGGDKGEDG 1339
Query: 440 --GFP----------PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQC 487
G P P GP G RG P G + R G+ + +
Sbjct: 1340 DPGQPGPPGPSGEAGPPGPPGKRG-PPGAAGAEGRQGE---------------KGAKGEA 1383
Query: 488 KAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRG 545
A P G P P G G+ GP G+RG G + ++G PG + G G G G G
Sbjct: 1384 GAEGPPGKTGPVGPQ--GPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPG 1441
Query: 546 GRGMDRGGFGGGRRGGPG-----GPPGPLMEQMGGRRGGRGGPG 584
+G D G G +G PG GPPG EQ G +G RG PG
Sbjct: 1442 LKG-DPG--SKGEKGHPGLIGLIGPPG---EQ--GEKGDRGLPG 1477
Score = 70.9 bits (172), Expect = 3e-12
Identities = 122/456 (26%), Positives = 154/456 (33%), Gaps = 62/456 (13%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G P + G G + G P P + GS A
Sbjct: 1033 GLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTA----------------------GP 1070
Query: 219 MGVYGQESGGFSGPGENRSMSGPDNRG-RGRGGFD--RGGMSRGGRGGGRGGMGSAGERG 275
+G+ G+ G PG P +G +G G D +G + G G G G G++G
Sbjct: 1071 IGLPGRP-GPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKG 1129
Query: 276 GFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNK 335
+PG +G + GPP P A + G + F Q G
Sbjct: 1130 EIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARG 1189
Query: 336 RTGQPMIHIYLDKETGKP-----KGDATVSYEDPPTAKAAVEWFDGKDF-QGSKLKVS-- 387
G P I L G P GD P + +G D QG V
Sbjct: 1190 FPGPPG-PIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSV 1248
Query: 388 --LARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG--GDRGGFPP 443
+ K P + G P G G P RG G GP G G G +G GD G
Sbjct: 1249 GGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKG-EAGPPGAAGPPGAKGPPGDDGPKGN 1307
Query: 444 RGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPP- 502
GP G G+P G D G G + Q P P G PP PP
Sbjct: 1308 PGPVGFPGDPGPPGEPGPAGQD------GVGGDK-GEDGDPGQPGPPGPSGEAGPPGPPG 1360
Query: 503 ---PGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRG-MDRGG 553
P G G G G +G +G G PG G G G G RG G + G
Sbjct: 1361 KRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQG 1420
Query: 554 FGG--GRRGGPG--GPPG-PLMEQMGGRRGGRGGPG 584
G G+ G PG GPPG P ++ G +G +G PG
Sbjct: 1421 LPGAAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPG 1456
Score = 70.5 bits (171), Expect = 4e-12
Identities = 84/264 (31%), Positives = 98/264 (37%), Gaps = 44/264 (16%)
Query: 361 YEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGG 420
YED PT+ E+ G + + S+ + G P GM L GP G
Sbjct: 389 YEDKPTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGM---LVEGPPG 445
Query: 421 PGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGG---------NVQHRAGDWQCP 469
P GP G MG G +G G G RGP G G P G + R G
Sbjct: 446 PAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 505
Query: 470 NPGCGNQNFAWRTECNQCKA-----PKPEGFLPPPFPPPG-------GDRGRGGPGGMRG 517
P Q + Q + P P G P P G G+ G GP G RG
Sbjct: 506 GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 565
Query: 518 GRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGMDRGGFGG-----GRRG--GPGGP 565
+G G PG R G G RG G +G RG D G G G RG GP GP
Sbjct: 566 VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFD--GLPGLPGDKGHRGERGPQGP 623
Query: 566 PGPL----MEQMGGRRGGRGGPGK 585
PGP M G G RG PG+
Sbjct: 624 PGPPGDDGMRGEDGEIGPRGLPGE 647
Score = 67.4 bits (163), Expect = 4e-11
Identities = 106/411 (25%), Positives = 131/411 (31%), Gaps = 83/411 (20%)
Query: 154 QQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQA-----PSQYSQQSSSYGQQ 208
QQ +GQ G + G G Q P + G P +
Sbjct: 1175 QQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNG 1234
Query: 209 SSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGM 268
+ Q P S+G G G PGE + P G G +RG G G G
Sbjct: 1235 ADGPQGPPGSVGSVGGV-GEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPP 1293
Query: 269 GSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQC 328
G+ G G G P G D GPP +P Q
Sbjct: 1294 GAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAG------------------------QD 1329
Query: 329 GVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSK-LKVS 387
GV G P + G P PP + + QG K K
Sbjct: 1330 GVGGDKGEDGDP-------GQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1382
Query: 388 LARKKPPMNS------MRGGLPPREG-RGMPPPL--RGGPGGPG--GPGGPMGRMG--GR 434
+ PP + G P EG RG+P P+ +G PG G GP GPMG G G
Sbjct: 1383 AGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGL 1442
Query: 435 GGDRGGFPPRGPRGSRGNPS-----GGGNVQHRAGDWQCP----NPGCGNQNFAWRTECN 485
GD G +G +G+P G Q GD P +PG
Sbjct: 1443 KGDPGS------KGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDG-------- 1488
Query: 486 QCKAPKPEGFLPPPFPP-------PGGDRGRGGPGGMRGGRGGLMDRGGPG 529
P P G L PP PP P G++G GP G +G G G PG
Sbjct: 1489 --GIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPG 1537
Score = 65.5 bits (158), Expect = 1e-10
Identities = 105/408 (25%), Positives = 131/408 (32%), Gaps = 81/408 (19%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQSSFRQDHPS 217
G+P GQQ +GQ+ G + P G P ++ G P
Sbjct: 1168 GEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPR 1227
Query: 218 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGF 277
G PG S+ G +G + G G GG +G G GE G
Sbjct: 1228 GPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPP 1287
Query: 278 NKPGGPMDEGPDLDLGP---------PVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQC 328
G P +GP D GP P DP + G+ D
Sbjct: 1288 GAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDG-------- 1339
Query: 329 GVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSK-LKVS 387
GQP G P PP + + QG K K
Sbjct: 1340 -------DPGQP----------GPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGE 1382
Query: 388 LARKKPPMNSMR------GGLPPREG-RGMPPPL--RGGPGGPG--GPGGPMGRMG--GR 434
+ PP + G P EG RG+P P+ +G PG G GP GPMG G G
Sbjct: 1383 AGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGL 1442
Query: 435 GGDRGGFPPRGPRGSRGNPS-----GGGNVQHRAGDWQCP----NPGCGNQNFAWRTECN 485
GD G +G +G+P G Q GD P +PG
Sbjct: 1443 KGDPGS------KGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDG-------- 1488
Query: 486 QCKAPKPEGFLPPPFPP----PGGDRGRGGPGGMRGGRGGLMDRGGPG 529
P P G L PP PP P G +G G G G +G D G PG
Sbjct: 1489 --GIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKG---DSGLPG 1531
Score = 61.6 bits (148), Expect = 2e-09
Identities = 68/188 (36%), Positives = 76/188 (40%), Gaps = 23/188 (12%)
Query: 408 RGMPPP--LRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRG---PRGSRGNPSGGGNVQHR 462
RG P P L G PG GGPG + G GD G PRG P G G P G
Sbjct: 528 RGPPGPMGLTGRPGPVGGPGSSGAK--GESGDPGPQGPRGVQGPPGPTGKPGKRGRPGAD 585
Query: 463 AGDWQCPNPGC-GNQNFAWRTECNQCKAPKPE-GFLPPPFPPPGGDRGRGGPGGMRGGRG 520
G PG G++ F K + E G PP PP G GMRG G
Sbjct: 586 GGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPP--------GDDGMRGEDG 637
Query: 521 GLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRG--GPGGPPGPLMEQMGGR 576
+ RG PG G G RG G G GM G +G GP G PGP +Q G
Sbjct: 638 EIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQ--GN 695
Query: 577 RGGRGGPG 584
G +G PG
Sbjct: 696 PGPQGLPG 703
Score = 37.0 bits (84), Expect = 0.052
Identities = 66/246 (26%), Positives = 78/246 (31%), Gaps = 34/246 (13%)
Query: 216 PSSMGVYGQES-GGFSGPGENRSMSGPDNRGRGRGG----FDRGGMSRGGRGGGRGGMGS 270
P G GQ+ GG G + GP G RG G G +G G+
Sbjct: 1320 PGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGA 1379
Query: 271 AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGV 330
GE G PG GP G P + QGL + D G+
Sbjct: 1380 KGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGL 1439
Query: 331 VKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSL-A 389
+ G E G P + PP QG K L
Sbjct: 1440 PGLKGDPGSK-------GEKGHP---GLIGLIGPPGE------------QGEKGDRGLPG 1477
Query: 390 RKKPPMNSMRGGLP-PREGRGMP-PPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPR 447
+ P GG+P P G P PP GP GP G G G G +G G P GP
Sbjct: 1478 TQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGD--SGLP--GPP 1533
Query: 448 GSRGNP 453
GS G P
Sbjct: 1534 GSPGPP 1539
Score = 33.1 bits (74), Expect = 0.75
Identities = 50/224 (22%), Positives = 74/224 (33%), Gaps = 31/224 (13%)
Query: 114 AQSAYGTQPAYPAYGQQPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQ 173
A A G Q A G+ A P P + G P G+Q G
Sbjct: 1367 AAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQG-PAGKPGPEGLRGIPGPVGEQGLPGAA 1425
Query: 174 SSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPG 233
G P P G S+ G++ HP +G+ G G G
Sbjct: 1426 GQDGPPGPMGPPGLPGLKGDPGSK--------GEKG-----HPGLIGLIGPP--GEQGEK 1470
Query: 234 ENRSMSGPDNR--GRGRGGFDRGGMSRGGRG-----------GGRGGMGSAGERGGFNKP 280
+R + G +G GG G G G +G G AG++G P
Sbjct: 1471 GDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLP 1530
Query: 281 GGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADF 324
G P GP ++ P+ P S + + +G+ D++ D+
Sbjct: 1531 GPPGSPGPPGEVIQPL-PILSSKKTRRHTEGMQADAD-DNILDY 1572
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 88.2 bits (217), Expect = 2e-17
Identities = 132/482 (27%), Positives = 166/482 (34%), Gaps = 77/482 (15%)
Query: 130 QPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTG 189
+P T P T PT G P G G Q S G P Q G
Sbjct: 2208 EPGETGPPGRGLTGPTG----------AVGLPGPPGPSGLVGPQGSPG------LPGQVG 2251
Query: 190 SYSQ--APSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR-GR 246
+ AP + +S + S GV G S G GP + GP G+
Sbjct: 2252 ETGKPGAPGR---------DGASGKDGDRGSPGVPG--SPGLPGPVGPKGEPGPTGAPGQ 2300
Query: 247 GRGGFDRGGMSRGGRGGGRGGM-GSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNS 305
G +G GG G + G G +G PG ++G G P DP ED
Sbjct: 2301 AVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKG 2360
Query: 306 AIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPP 365
A +G FK V + G P G P + P
Sbjct: 2361 APGPKG-------------FKGDPGVGVPGSPGPP----------GPPGVKGDLGLPGLP 2397
Query: 366 TAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG 425
A V F G+ ++ +P + RG P G+P PL GP GP G
Sbjct: 2398 GAPGVVG-FPGQTGPRGEMG------QPGPSGERGLAGPPGREGIPGPL--GPPGPPGSV 2448
Query: 426 GPMGRMGGRG--GDRG-GFPPRGPRGSRGNPS--GGGNVQHRAGDWQCPNPGCGNQNFAW 480
GP G G +G GD G G P GPRG RG P G + G P
Sbjct: 2449 GPPGASGLKGDKGDPGVGLP--GPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGE 2506
Query: 481 RTECNQCKAPKPEGFLPPPFPPPG-----GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGG 535
+ + +G PPG GD G GP G+ G +G D G PG G
Sbjct: 2507 KGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKG 2566
Query: 536 RGGDRG--GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQ 593
GD+G G G RG+ G G PG P P + + G RG +G G M +
Sbjct: 2567 EPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKG 2626
Query: 594 ER 595
ER
Sbjct: 2627 ER 2628
Score = 82.8 bits (203), Expect = 8e-16
Identities = 127/465 (27%), Positives = 160/465 (34%), Gaps = 78/465 (16%)
Query: 141 STQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQ 200
+TQP Y + G+P G + G G T P G A ++
Sbjct: 1239 TTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAK--- 1295
Query: 201 QSSSYGQQSSFRQD-HPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRG 259
G++ D P S G G G PG S P RG D G RG
Sbjct: 1296 -----GERGFPGADGRPGSPGRAGNP-GTPGAPGLKGSPGLPGPRG------DPG--ERG 1341
Query: 260 GRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLD 319
RG +G G+ G+ G PG P +G GPP D GL +
Sbjct: 1342 PRGP-KGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKG 1400
Query: 320 DLADFFKQ--CGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGK 377
D D ++ G + G+P + G P PP K
Sbjct: 1401 DKGDRGERGPPGPGEGGIAPGEPGL-------PGLPGSPGPQGPVGPPGKKG-------- 1445
Query: 378 DFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG----- 432
+K GLP + G P GP GP G GP G G
Sbjct: 1446 -------------EKGDSEDGAPGLPGQPG----SPGEQGPRGPPGAIGPKGDRGFPGPL 1488
Query: 433 GRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKP 492
G G++G P GP GSRG P G + G P P G Q E + P
Sbjct: 1489 GEAGEKGERGPPGPAGSRGLPGVAGRPGAK-GPEGPPGP-TGRQG-----EKGEPGRPGD 1541
Query: 493 EGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRG-----GDRG--GFRG 545
+ P P G++G GP G RG G +RG PG + G G GDRG G G
Sbjct: 1542 PAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTG 1601
Query: 546 GRGMDRGGFGGGRRGGPG--GPPGPL----MEQMGGRRGGRGGPG 584
G G +G PG GPPGP+ + G +G G PG
Sbjct: 1602 RAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPG 1646
Score = 80.5 bits (197), Expect = 4e-15
Identities = 138/494 (27%), Positives = 173/494 (35%), Gaps = 100/494 (20%)
Query: 148 DQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQ 207
DQ + G P S G + G+ G P TG ++ + + +
Sbjct: 1674 DQGDPGEDGRNGSPGSSGPKGDRGEPGPPG---PPGRLVDTGPGAREKGEPGDRGQEGPR 1730
Query: 208 QSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGG 267
P + G G E GF GP GP D G G G RG
Sbjct: 1731 GPKGDPGLPGAPGERGIE--GFRGP------PGPQG--------DPGVRGPAGEKGDRGP 1774
Query: 268 MGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQ 327
G G G KPG GP+ G DP D QGL L +
Sbjct: 1775 PGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGE 1834
Query: 328 CGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVS 387
G +N + G+P G P D E + + E DG + +
Sbjct: 1835 DGKPGLNGKNGEP----------GDPGEDGRKG-EKGDSGASGREGRDGPKGERGAPGI- 1882
Query: 388 LARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPG--GPGGPMGRMGGRGGDRGGFPPRG 445
L + PP GLP G PP +G PG PG GP G G G +G G P G
Sbjct: 1883 LGPQGPP------GLPGPVG----PPGQGFPGVPGGTGPKGDRGETGSKG--EQGLP--G 1928
Query: 446 PRGSRGNPSGGGNVQ---HRAG-----------DWQ------CPNPGCGNQNFAWRTECN 485
RG RG P NV AG W P P + + +
Sbjct: 1929 ERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVP---ERRRGPKGDSG 1985
Query: 486 QCKAPKPEGFL--------------PPPFPPPG---GDRGRGGPGGMRG--GRGGLMD-R 525
+ P EG + P P PPG G+RG GP G+ G G+ G+
Sbjct: 1986 EQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLP 2045
Query: 526 GGPGGMFRGGRGGDRG-----GFRGGRGMDRGGFGGGRRGGPGGPPGPLM---EQMGGRR 577
G GG+ GR G+RG G RG +G D G G GP GPPGP + E G
Sbjct: 2046 GRAGGVGEAGRPGERGERGEKGERGEQGRD-GPPGLPGTPGPPGPPGPKVSVDEPGPGLS 2104
Query: 578 GGRGGPG-KMDKGE 590
G +G PG K KGE
Sbjct: 2105 GEQGPPGLKGAKGE 2118
Score = 79.7 bits (195), Expect = 7e-15
Identities = 142/521 (27%), Positives = 177/521 (33%), Gaps = 108/521 (20%)
Query: 122 PAYPAYGQQPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPP 181
P P P P ++ + + + + G+ + G + G + S G P
Sbjct: 1274 PGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGP 1333
Query: 182 TSYPPQTGSYSQA--PSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMS 239
P + G P Q G R+ P G G G PG
Sbjct: 1334 RGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPR-GPLGDPGPRGPPG 1392
Query: 240 GPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPD 299
P +G G DRG RG G G GG+ + GE G PG P +GP +GPP
Sbjct: 1393 LPGTAMKGDKG-DRG--ERGPPGPGEGGI-APGEPGLPGLPGSPGPQGP---VGPPGKKG 1445
Query: 300 EDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATV 359
E D+ G P + G+P
Sbjct: 1446 EKGDSE-------------------------------DGAPGL-------PGQPGSPGEQ 1467
Query: 360 SYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPG 419
PP A K +G + A +K RG P RG+P + G PG
Sbjct: 1468 GPRGPPGA------IGPKGDRGFPGPLGEAGEK----GERGPPGPAGSRGLPG-VAGRPG 1516
Query: 420 --GPGGPGGPMGRMG-----GRGGDRGGFPPR--GPRGSRGN-----PSGGGNVQHRAGD 465
GP GP GP GR G GR GD P GP+G +G+ P G VQ G
Sbjct: 1517 AKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGP 1576
Query: 466 WQCPNPGCGNQNF--AWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRG--GRGG 521
PG R P G PP GD GR GP G G GR G
Sbjct: 1577 PGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEK--GDPGRPGPPGPVGPRGRDG 1634
Query: 522 LM----DRGGPGGMFRGGRGGDRG-----GFRG--GRGMDRGGFG-GGRRGGPG------ 563
+ D G PG G+ G+RG G RG G D+G G GR G PG
Sbjct: 1635 EVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKG 1694
Query: 564 -----GPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRP 599
GPPGP GR GPG +KGE ++ P
Sbjct: 1695 DRGEPGPPGP-----PGRLVDT-GPGAREKGEPGDRGQEGP 1729
Score = 79.7 bits (195), Expect = 7e-15
Identities = 135/551 (24%), Positives = 184/551 (33%), Gaps = 102/551 (18%)
Query: 72 QPPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGTQPAYPAYGQQP 131
Q P G P P P GTG T + + + +P +
Sbjct: 1886 QGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRL 1945
Query: 132 AATAPTSYSSTQPT--SYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTG 189
TA S+ + ++D+SS S G + G+Q G++ P +P + G
Sbjct: 1946 LETAGIKASALREIVETWDESSGSFLPV--PERRRGPKGDSGEQGPPGKEGPIGFPGERG 2003
Query: 190 SYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRG 249
+ P G G G PG + P G
Sbjct: 2004 LKGD-------------------RGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGL 2044
Query: 250 GFDRGGMSRGGRGGGRGGMGSAGERGGFNK---PGGPMDEGPDLDLGPPVDPDEDSDNSA 306
GG+ GR G RG G GERG + PG P GP GP V DE
Sbjct: 2045 PGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGP--- 2101
Query: 307 IYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPT 366
GL+ + G + G+P + + G PKGD V
Sbjct: 2102 ----GLSG------------EQGPPGLKGAKGEPGSN----GDQG-PKGDRGVPGIKGDR 2140
Query: 367 AKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPP------------- 413
+ DG + ++ KP + RG P G G P P
Sbjct: 2141 GEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQ 2200
Query: 414 ----LRGGPGGPGGPG----GPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGD 465
L+G PG G PG GP G +G G P GP G G P G + + G
Sbjct: 2201 GPSGLKGEPGETGPPGRGLTGPTGAVGLPG-------PPGPSGLVG-PQGSPGLPGQVG- 2251
Query: 466 WQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGR-----G 520
+ PG ++ A + ++ P P P P G +G GP G G G
Sbjct: 2252 -ETGKPGAPGRDGASGKDGDRGSPGVPGS---PGLPGPVGPKGEPGPTGAPGQAVVGLPG 2307
Query: 521 GLMDRGGPGGMF-----RGGRGGDRG--GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQM 573
++G PGG+ G GDRG G RG +G GR G PG P +
Sbjct: 2308 AKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKG------EAGRAGEPGDPGEDGQKGA 2361
Query: 574 GGRRGGRGGPG 584
G +G +G PG
Sbjct: 2362 PGPKGFKGDPG 2372
Score = 79.3 bits (194), Expect = 9e-15
Identities = 114/387 (29%), Positives = 133/387 (34%), Gaps = 77/387 (19%)
Query: 233 GENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLD- 291
G+N P GR D G R GR G +G G+ G G PG P GP
Sbjct: 1842 GKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQG 1901
Query: 292 -------LGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHI 344
GP D E QGL L G+P
Sbjct: 1902 FPGVPGGTGPKGDRGETGSKGE---QGLPGERGL------------------RGEPGSVP 1940
Query: 345 YLDK--ETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGL 402
+D+ ET K A + VE +D + GS L V R+ P +S G
Sbjct: 1941 NVDRLLETAGIKASAL---------REIVETWD--ESSGSFLPVPERRRGPKGDSGEQGP 1989
Query: 403 PPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHR 462
P +EG P RG G G PG P G G G+RG P G G G P G
Sbjct: 1990 PGKEGPIGFPGERGLKGDRGDPG-PQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRA 2048
Query: 463 AGDWQCPNPGCGNQ--NFAWRTECNQCKAPKPEGFLPPPFPP------------------ 502
G + PG + R E + P G PP PP
Sbjct: 2049 GGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQG 2108
Query: 503 PGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGMDRGGFGGG 557
P G +G G G G +G DRG PG G G RG G G RGM G G
Sbjct: 2109 PPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGM-AGPEGKP 2167
Query: 558 RRGGPGGPPGPLMEQMGGRRGGRGGPG 584
GP GPPGP+ GG G PG
Sbjct: 2168 GLQGPRGPPGPV--------GGHGDPG 2186
Score = 70.1 bits (170), Expect = 6e-12
Identities = 105/377 (27%), Positives = 134/377 (35%), Gaps = 84/377 (22%)
Query: 260 GRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLD 319
G+ G RG MG G G G P EG LGPP P A ++G
Sbjct: 2407 GQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKG-------- 2458
Query: 320 DLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKA-AVEWFD--G 376
D D G+ G+P I E G+P + PP ++ E D
Sbjct: 2459 DKGD--PGVGLPGPRGERGEPGIR----GEDGRPGQEGPRGLTGPPGSRGERGEKGDVGS 2512
Query: 377 KDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMP------------------------- 411
+G K ++ P +G + R RG+
Sbjct: 2513 AGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKG 2572
Query: 412 ----PPLRG--GPGG-------PGGPGGPMGRMG-----GRGGDRGGFPPRGPRGSRGNP 453
P LRG GP G PG PG P G+ G G GD G PRG +G RG
Sbjct: 2573 SAGLPGLRGLLGPQGQPGAAGIPGDPGSP-GKDGVPGIRGEKGDVGFMGPRGLKGERGVK 2631
Query: 454 SGGGNVQHRAGDWQCPNPG----CGNQNFAWRTEC-NQCKAPKPEGFLPPPFPPPGGDRG 508
G + + PG G++ Q AP EG + P GDRG
Sbjct: 2632 GACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPK-----GDRG 2686
Query: 509 RGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGP 568
G G +G +G +RG PG GGF G G D G G G GP GP
Sbjct: 2687 FDGQPGPKGDQGEKGERGTPG----------IGGFPGPSGND-GSAGPPGPPGSVGPRGP 2735
Query: 569 LMEQMGGRRGGRGGPGK 585
E + G++G RG PG+
Sbjct: 2736 --EGLQGQKGERGPPGE 2750
Score = 64.3 bits (155), Expect = 3e-10
Identities = 68/190 (35%), Positives = 76/190 (40%), Gaps = 28/190 (14%)
Query: 404 PREGRGMPPP--LRGGPGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNV 459
P+ +G P LRG G PG PG P GR G G G G +G RG G G+
Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPGDPGLP-GRTGAPGPQGPPGSATAKGERGFPGADGRPGS- 1309
Query: 460 QHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGR 519
RAG NPG AP +G P P P GD G GP G +G
Sbjct: 1310 PGRAG-----NPGTPG-------------APGLKG--SPGLPGPRGDPGERGPRGPKGEP 1349
Query: 520 GGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGG 579
G G G GR GD G G RG G GP G PG M+ G RG
Sbjct: 1350 GAPGQVIGGEGPGLPGRKGDPGP--SGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGE 1407
Query: 580 RGGPGKMDKG 589
RG PG + G
Sbjct: 1408 RGPPGPGEGG 1417
Score = 61.6 bits (148), Expect = 2e-09
Identities = 112/447 (25%), Positives = 146/447 (32%), Gaps = 95/447 (21%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
GQP G++ G G P P GS + S G + P
Sbjct: 2416 GQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGA-----SGLKGDKGDPGVGLPGP 2470
Query: 219 MGVYGQES--GGFSGPGEN--RSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGG----MGS 270
G G+ G PG+ R ++GP RG ++G + G G +G +G
Sbjct: 2471 RGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERG--EKGDVGSAGLKGDKGDSAVILGP 2528
Query: 271 AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGV 330
G RG G G D D GP D + D + G S L L G
Sbjct: 2529 PGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQ 2588
Query: 331 VKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSK-LKVSLA 389
G P G P D K V + + +G + +K +
Sbjct: 2589 PGAAGIPGDP----------GSPGKDGVPGIRGE---KGDVGFMGPRGLKGERGVKGACG 2635
Query: 390 RKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG--GRGGDRGGFPPRGPR 447
+ G P R G G PG PG G P G+ G G GDRG GP+
Sbjct: 2636 LDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAP-GKEGLIGPKGDRGFDGQPGPK 2694
Query: 448 GSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDR 507
G +G G PG G FP P G+
Sbjct: 2695 GDQGEKGERGT------------PGIGG------------------------FPGPSGND 2718
Query: 508 GRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPG 567
G GP G PG + G RG + G +G +G +RG G G PG P
Sbjct: 2719 GSAGP------------PGPPGSV--GPRGPE--GLQGQKG-ERGPPGERVVGAPGVPGA 2761
Query: 568 PLMEQMGGRRGGRGGPG----KMDKGE 590
P G RG +G PG + +KGE
Sbjct: 2762 P------GERGEQGRPGPAGPRGEKGE 2782
Score = 50.4 bits (119), Expect = 5e-06
Identities = 38/101 (37%), Positives = 44/101 (43%), Gaps = 8/101 (7%)
Query: 490 PKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----GFR 544
P+PE P P P G +G G G+RG G D G PG G G G G R
Sbjct: 1242 PRPE---PCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGER 1298
Query: 545 GGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 585
G G D GR G PG P P ++ G G RG PG+
Sbjct: 1299 GFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGE 1339
>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
Length = 1860
Score = 87.8 bits (216), Expect = 3e-17
Identities = 136/468 (29%), Positives = 174/468 (37%), Gaps = 81/468 (17%)
Query: 158 YGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTG-------SYSQAPSQYSQQSSSYGQQSS 210
YG P G + GQ+ G P ++ G S + P G
Sbjct: 660 YGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAG- 718
Query: 211 FRQDHPSSMGVYGQE-SGGFSGPGENRSMSGP--DNRGRG-RGGFDRGGM-----SRGGR 261
HP G G E S G G + + GP D +G RG G+ S G R
Sbjct: 719 ----HPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGER 774
Query: 262 G-----GGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSV 316
G G RG MG G G F + G P +G +LG P P V GL +
Sbjct: 775 GLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPG---------VPGLIGDL 825
Query: 317 TLDDLADFFKQCGVVKMNKRTGQPMIHIYLDK-ETGKPKGDATVSYEDPPTAKAAVEWFD 375
+ + G+ + G+P + DK E G P ++ ++ +
Sbjct: 826 GVLGPIGYPGPKGMKGLMGSVGEPGLKG--DKGEQGVPGVSGDPGFQGDKGSQGLPGFPG 883
Query: 376 GKDFQGSKLKV----SLARKKPP-MNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGR 430
+ G KV S+ PP G + P G P ++G PG G PG P G+
Sbjct: 884 ARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNG-PEGMKGKPGARGLPG-PRGQ 941
Query: 431 MGGRGGDRGGFPPRGPRGSRGNPSGGG--------NVQHRAGDWQCPNPGCGNQNFAWRT 482
+G G D G P G G G P G V+ GD P P G Q F
Sbjct: 942 LGPEG-DEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGP-VGEQGFM--- 996
Query: 483 ECNQCKAPKPEGFL----PPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGG 538
GF+ P GDRG GP G+ G +G + G PGGM G G
Sbjct: 997 -----------GFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPG 1045
Query: 539 DRG--GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPG 584
+G G RG GM RG G R GP GP GP EQ G RG +G PG
Sbjct: 1046 PQGPPGSRGPPGM-RGAKG---RRGPRGPDGPAGEQ--GSRGLKGPPG 1087
Score = 83.2 bits (204), Expect = 6e-16
Identities = 129/462 (27%), Positives = 160/462 (34%), Gaps = 131/462 (28%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFR----QD 214
G P G+ GQ+ G+ P P TG + P S + G+ + Q
Sbjct: 1207 GDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGV--RGPEGKSGKQGEKGRTGAKGAKGYQG 1264
Query: 215 HPSSMGVYGQESG-GFSGPGENRSMSGPDNR-GR-------GRGGFD--RGGMSRGGRGG 263
MGV G G GP +R GP GR G G+D +G + G G
Sbjct: 1265 QLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPG 1324
Query: 264 GRGGMGSAGERG-GFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLA 322
+G G GE G PG P D GP D G +P + VQGL
Sbjct: 1325 PKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLR--------- 1375
Query: 323 DFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGS 382
G+P + G+P + P +K A +G
Sbjct: 1376 ---------------GKP-------GQQGQPGHPGPRGWPGPKGSKGA---------EGP 1404
Query: 383 KLKVSLARKKPPMNSMRGGLPPREG----RGMPPPL----RGGPGGPGGPGGPMGRMG-- 432
K K A G P R G +G+P P R G G GP G GR G
Sbjct: 1405 KGKQGKA-----------GAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQA 1453
Query: 433 ---GRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKA 489
G GD G P GP G RGNP G
Sbjct: 1454 GQQGEQGDDGDPGPMGPAGKRGNPGVAG-------------------------------L 1482
Query: 490 PKPEGFLPPPFPPPGGDRGRGGPGGMRG--GRGGLM-DRGGPGGMFRGGRGGDRGGFRGG 546
P +G PP F G G+ GP G RG GR GL ++G PG + G G+ GF G
Sbjct: 1483 PGAQG--PPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEM-GFPGM 1539
Query: 547 RGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDK 588
G+ GP GPPG + G +G RG PG M K
Sbjct: 1540 AGL----------FGPKGPPGDI--GFKGIQGPRGPPGLMGK 1569
Score = 80.1 bits (196), Expect = 5e-15
Identities = 140/504 (27%), Positives = 167/504 (33%), Gaps = 107/504 (21%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS-QAPSQYSQQSSSYGQQS----SFRQ 213
G P G G Q G + P G + P + + S G + R
Sbjct: 1033 GMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRP 1092
Query: 214 DHPSSMGVYGQE----SGGFSG-PGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGM 268
P GV G+ S GF G PG SGP +G G + G G G G M
Sbjct: 1093 GRPGQQGVAGERGHLGSRGFPGIPGP----SGPPGT-KGLPG-EPGPQGPQGPIGPPGEM 1146
Query: 269 GSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQC 328
G G G +PG P + G DLGP P E QGL L
Sbjct: 1147 GPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGE---------QGLIGQRGEPGLEGDSGPM 1197
Query: 329 GVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKD----FQGSKL 384
G + G P D E G+ KG + ED P V G + QG K
Sbjct: 1198 GPDGLKGDRGDP----GPDGEHGE-KGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKG 1252
Query: 385 KVSLARKK--------------------PPMNSMRG-----GLPPREGRGMPPPLRGGPG 419
+ K P RG G P R G P L G G
Sbjct: 1253 RTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDG 1312
Query: 420 -----GPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCG 474
GP GP GP G G +G D P GP G RG P G + GD PG
Sbjct: 1313 HKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRG-PVGDRGDRGEPGD-----PGYP 1366
Query: 475 NQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRG----------------- 517
Q + +P P +P P G +G GP G +G
Sbjct: 1367 GQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLP 1426
Query: 518 ------GRGGLMDRGGPGGM-FRGGRGGDRGGFRGGRGMDRGGFG-GGRRGGPG------ 563
GR GL GP G+ R G+ G +G G D G G G+RG PG
Sbjct: 1427 GPRGVVGRQGLEGIAGPDGLPGRDGQAGQQG--EQGDDGDPGPMGPAGKRGNPGVAGLPG 1484
Query: 564 --GPPGPLMEQMGGRRGGRGGPGK 585
GPPG + G G G PGK
Sbjct: 1485 AQGPPG--FKGESGLPGQLGPPGK 1506
Score = 73.9 bits (180), Expect = 4e-13
Identities = 122/440 (27%), Positives = 153/440 (34%), Gaps = 97/440 (22%)
Query: 216 PSSMGVYGQESG-GFSGPGENRSMSGP-----DNRGRGRGGFDRGGMSRGGRG--GGRGG 267
P +G G + GF GP G DN G G G RG G RG
Sbjct: 888 PGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKG------KPGARGLPGPRGQ 941
Query: 268 MGSAGERGGFNKPGGPMDEG----------PDLDLGPPVDPDEDSDNSAIYVQGLNDSVT 317
+G G+ G PG P EG P LD G +P + + QG +
Sbjct: 942 LGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLD-GVKGEPGDPGRPGPVGEQGFMGFIG 1000
Query: 318 LDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSY---EDPPTAKAAVEWF 374
L + G M G P + G P G T + PP ++
Sbjct: 1001 LVGEPGIVGEKGDRGMMGPPGVPGPKGSMG-HPGMPGGMGTPGEPGPQGPPGSRGPPGMR 1059
Query: 375 DGKDFQGSK-------LKVSLARKKPPMNSMRGGLPPREG----------RGMP------ 411
K +G + + S K PP R G P ++G RG P
Sbjct: 1060 GAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPS 1119
Query: 412 --PPLRG-----GPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAG 464
P +G GP GP GP GP G MG P+GP G+ G P G +
Sbjct: 1120 GPPGTKGLPGEPGPQGPQGPIGPPGEMG----------PKGPPGAVGEPGLPGEAGMKGD 1169
Query: 465 DWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPG--GDRGRGGPGGMRGGRG-- 520
P G Q Q P EG P P G GDRG GP G G +G
Sbjct: 1170 LGPLGTP--GEQGL-----IGQRGEPGLEGD-SGPMGPDGLKGDRGDPGPDGEHGEKGQE 1221
Query: 521 GLMDRGGP----------GGMFRGGRGGDRG--GFRGGRGM--DRGGFGGGRRGGPGGPP 566
GLM GP G + G+ G++G G +G +G G G GP G P
Sbjct: 1222 GLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTP 1281
Query: 567 GPLMEQMGGRRGGRGGPGKM 586
GP + G G G PG+M
Sbjct: 1282 GP--KGSRGSLGPTGAPGRM 1299
Score = 65.9 bits (159), Expect = 1e-10
Identities = 128/458 (27%), Positives = 150/458 (32%), Gaps = 107/458 (23%)
Query: 216 PSSMGVYGQESG-GFSG-PGENRSMSGPDNRGR----GRGGF-----------------D 252
P + G+ GQ GF G PG + P + GR G GF D
Sbjct: 954 PGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGD 1013
Query: 253 RGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGL 312
RG M G G +G MG G GG PG P GP GPP A +G
Sbjct: 1014 RGMMGPPGVPGPKGSMGHPGMPGGMGTPGEP---GPQ---GPPGSRGPPGMRGA---KGR 1064
Query: 313 NDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVE 372
D A G+ G+P G+P G V+ E
Sbjct: 1065 RGPRGPDGPAGEQGSRGLKGPPGPQGRP----------GRP-GQQGVAGERGHLGSRGFP 1113
Query: 373 WFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPRE-GRGMPPPLRGGPGGPGGPG-----G 426
G G L + P PP E G PP G PG PG G G
Sbjct: 1114 GIPGPS--GPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLG 1171
Query: 427 PMGRMGGRG-----------GDRGGFPPRGPRGSRGNPSGGGNVQHRA-----GDWQCPN 470
P+G G +G GD G P G +G RG+P G + G+ P
Sbjct: 1172 PLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPG 1231
Query: 471 PG-----------CGNQNFAWRTECNQCKAPK--------PEGFLPPPFPPPGGDRGRGG 511
P G Q RT K + P PP P P G RG G
Sbjct: 1232 PPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLG 1291
Query: 512 PGGMRG-----GRGGLMDRGG----------PGGMFRGGRGGDRGGFRGGRGM--DRGGF 554
P G G G GL G PG G G+ G G G DRG
Sbjct: 1292 PTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPV 1351
Query: 555 GG-GRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEH 591
G G RG PG P P E G +G RG PG+ + H
Sbjct: 1352 GDRGDRGEPGDPGYPGQE---GVQGLRGKPGQQGQPGH 1386
Score = 47.8 bits (112), Expect = 3e-05
Identities = 87/323 (26%), Positives = 109/323 (33%), Gaps = 77/323 (23%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSY-SQAPSQYSQQSSSYGQQS-SFRQDHP 216
GQ G + GQQ G P +P GS ++ P ++ + G++ Q P
Sbjct: 1367 GQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLP 1426
Query: 217 SSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGG 276
GV G++ G G ++GPD GR G G G G G MG AG+RG
Sbjct: 1427 GPRGVVGRQ--GLEG------IAGPDGLP-GRDG-QAGQQGEQGDDGDPGPMGPAGKRGN 1476
Query: 277 FNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKR 336
G P + GPP E + G + R
Sbjct: 1477 PGVAGLPGAQ------GPPGFKGESGLPGQLGPPGKRGT------------------EGR 1512
Query: 337 TGQPMIHIYLDKETGKP--KGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPP 394
TG P G+P KG S E G L K P
Sbjct: 1513 TGLP-------GNQGEPGSKGQPGDSGE-----------------MGFPGMAGLFGPKGP 1548
Query: 395 MNSMRGGLPPREGRGMPPPLRGGPG--------GPGGPGGPMGRMGGRGGDRGGFPPRGP 446
+ G +G PP L G G GP G GP G G RG D G PRGP
Sbjct: 1549 PGDI--GFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRG-DWGLQGPRGP 1605
Query: 447 RGSRGNPS----GGGNVQHRAGD 465
G RG P GG +Q + D
Sbjct: 1606 PGPRGRPGPPGPPGGPIQLQQDD 1628
Score = 33.5 bits (75), Expect = 0.57
Identities = 48/204 (23%), Positives = 68/204 (33%), Gaps = 18/204 (8%)
Query: 125 PAYGQQPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY 184
P P A P + ++ T G+ G Q G + G +
Sbjct: 1477 PGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQPGDSGEMGF 1536
Query: 185 PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR 244
P G + P G Q G+ G+E G GP + GP
Sbjct: 1537 PGMAGLFG--PKGPPGDIGFKGIQGP-----RGPPGLMGKE--GIVGP---LGILGPSGL 1584
Query: 245 GRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN 304
+G D+G G G RG G G G PGGP+ D DLG D+ +
Sbjct: 1585 PGPKG--DKGSRGDWGLQGPRGPPGPRGRPGPPGPPGGPIQLQQD-DLGAAFQTWMDT-S 1640
Query: 305 SAIYVQGLN--DSVTLDDLADFFK 326
A+ + + D + LD + FK
Sbjct: 1641 GALRPESYSYPDRLVLDQGGEIFK 1664
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 87.0 bits (214), Expect = 4e-17
Identities = 119/389 (30%), Positives = 152/389 (39%), Gaps = 54/389 (13%)
Query: 216 PSSMGVYGQESGGFSGPGENRSMSGPDNRG-----RGRGGFD--RGGMSRGGRGGGRGGM 268
P S G+ G+ G GP R + GP RGR G D RG + G G RG
Sbjct: 576 PGSGGLKGEP--GDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFD 633
Query: 269 GSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQC 328
G AG G G P GP GPP D E D+ + +GL L
Sbjct: 634 GLAGLPGEKGHRGDPGPSGPP---GPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPP 690
Query: 329 GVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSL 388
G TG +D + G PKG+ E P + G G + +
Sbjct: 691 GPPGPPGVTG-------MDGQPG-PKGNVGPQGEPGPPGQQGNPGAQG--LPGPQGAIGP 740
Query: 389 ARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG--GPMGRMGGRG--GDRGGFPPR 444
+K P+ + GLP GMP G G PG PG GP G GG+G G +G
Sbjct: 741 PGEKGPLG--KPGLP-----GMP----GADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYP 789
Query: 445 GPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPG 504
GPRG +G G + + PG + + + + P P G P
Sbjct: 790 GPRGVKGADGIRGLKGTKGEKGEDGFPGFKG-DMGIKGDRGEIGPPGPRGE-----DGPE 843
Query: 505 GDRGRGGPGGMRGGRGGLMDRGG---PGGMFRGGRGGDRG-----GFRGGRGMDRGGFGG 556
G +GRGGP G G G ++G PG GR G +G GF G G ++GG G
Sbjct: 844 GPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANG-EKGGRGT 902
Query: 557 GRRGGPGGPPGPLMEQMGGRRGGRGGPGK 585
+ GP G GP + G RG RG GK
Sbjct: 903 PGKPGPRGQRGPTGPR--GERGPRGITGK 929
Score = 82.4 bits (202), Expect = 1e-15
Identities = 127/455 (27%), Positives = 158/455 (34%), Gaps = 80/455 (17%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G+ GQ+ S G + G PT PQ PS + GQQ F Q
Sbjct: 1159 GEIGEPGQKGSKGDKGEQGPPGPTG--PQGPIGQPGPSGADGEPGPRGQQGLFGQK---- 1212
Query: 219 MGVYGQESG-GFSGPGENRSMSG-PDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERG- 275
G E GF GP + G P G D G M G G RG G+ G G
Sbjct: 1213 ----GDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGP 1268
Query: 276 -----GFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGV 330
G PG ++G + G P P E +G A G
Sbjct: 1269 QGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGP 1328
Query: 331 VKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLAR 390
+ G P + + G P + PP K DG+ Q
Sbjct: 1329 PGDDGPKGSPG-PVGFPGDPGPPGEPGPAGQDGPPGDKGD----DGEPGQT--------- 1374
Query: 391 KKPPMNSMRGGLPPREGRGMP--PPLRGGPGGPGGPGGPMGRMGGRG-----GDRGGFPP 443
G P G P PP + GP GP GP G G G +G G G P
Sbjct: 1375 ----------GSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGP 1424
Query: 444 RGPRGSRGNPSGGG--NVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFP 501
GP+G+ G P G + G+ P +P P+G P P
Sbjct: 1425 IGPQGAPGKPGPDGLRGIPGPVGEQGLPG------------------SPGPDG-PPGPMG 1465
Query: 502 PPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGG 557
PPG G +G GP G + G GL+ GP G G GDRG G +G G +G G
Sbjct: 1466 PPGLPGLKGDSGPKGEK-GHPGLIGLIGPPG--EQGEKGDRGLPGPQGSSG-PKGEQGIT 1521
Query: 558 RRGGPGGPPGPL-MEQMGGRRGGRGGPGKM-DKGE 590
GP GPPGP + G +G +G G KGE
Sbjct: 1522 GPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGE 1556
Score = 81.3 bits (199), Expect = 2e-15
Identities = 140/511 (27%), Positives = 175/511 (34%), Gaps = 111/511 (21%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G P G G Q G Q P YP G + + + + F
Sbjct: 763 GHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGF-PGFKGD 821
Query: 219 MGVYGQESG-GFSGPGENRSMSGPDNRGRGRG---------------------------- 249
MG+ G G GP GP RG G
Sbjct: 822 MGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGP 881
Query: 250 -------GFDRGGMSRGGRG--------GGRGGMGSAGERGG---FNKPGGPMDEGPDLD 291
GF +GGRG G RG G GERG KPG + G D
Sbjct: 882 KGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGP 941
Query: 292 LGPPVDPDEDSDNSAIYV---QGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDK 348
GPP + + +G D L Q G +TG P +
Sbjct: 942 AGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGP 1001
Query: 349 -----ETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLP 403
ETG P G+ P + + GK +G+K A GLP
Sbjct: 1002 QGPTGETG-PMGERGHPGPPGPPGEQGLPGLAGK--EGTKGDPGPA-----------GLP 1047
Query: 404 PREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRG--NPSGGG---N 458
++G PP LRG PG G P GP+G +G +G + PP GP GS G P+G
Sbjct: 1048 GKDG---PPGLRGFPGDRGLP-GPVGALGLKGNEGPPGPP-GPAGSPGERGPAGAAGPIG 1102
Query: 459 VQHRAGDWQCPNPG--------CGNQNFAWRTEC-NQCKAPKPEGFLPPPFPPPG--GDR 507
+ R G P P G Q A R P P G P PPG GD+
Sbjct: 1103 IPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAG----PVGPPGEDGDK 1158
Query: 508 GRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--------GFRGGRGMDRGGFGGGRR 559
G G G +G +G ++G PG G G G G RG +G+ G R
Sbjct: 1159 GEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPR 1218
Query: 560 GGPGGPPGPLMEQMGGRRGGRGGPGKMDKGE 590
G P GPPGP+ G +G G PG +KGE
Sbjct: 1219 GFP-GPPGPV-----GLQGLPGPPG--EKGE 1241
Score = 79.0 bits (193), Expect = 1e-14
Identities = 131/495 (26%), Positives = 160/495 (32%), Gaps = 66/495 (13%)
Query: 122 PAYPAYGQQPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPP 181
P + P + P D + G+P G G G
Sbjct: 639 PGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGV 698
Query: 182 TSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGP 241
T Q G Q + GQQ + P + G+ G + G PGE
Sbjct: 699 TGMDGQPGPKGNVGPQ--GEPGPPGQQGN-----PGAQGLPGPQ-GAIGPPGE------- 743
Query: 242 DNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDED 301
+G + + G G G G G G PG +GP GP P
Sbjct: 744 -----------KGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPR 792
Query: 302 SDNSAIYVQGLNDS---VTLDDLADFFKQCGVVKMNKRTGQPMIH----IYLDKETGKPK 354
A ++GL + D F G+ G P K G P
Sbjct: 793 GVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPN 852
Query: 355 GDATVSYEDPPTAKAAVEWFDG-KDFQGSKLKVSLARKKPPMNSMRG-----GLPPREGR 408
GD K V G QG K + P N +G G P G+
Sbjct: 853 GDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFP-GFPGANGEKGGRGTPGKPGPRGQ 911
Query: 409 GMPPPLRG--GPGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAG 464
P RG GP G G GP G GG G G G P GP+G G P G
Sbjct: 912 RGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGK 971
Query: 465 DWQCPNPG-CGNQNFAWRTECNQCKAPKPEGFLPPPFPP----PGGDRGRGGPGGMRGGR 519
D +PG G F +T P P G + P P P G+RG GP G G +
Sbjct: 972 DGLPGHPGQRGETGFQGKT-----GPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQ 1026
Query: 520 G--GLM----DRGGPGGMFRGGRGGDRG--GFRGGRGMDR--GGFGGGRRGGPGGPPGPL 569
G GL +G PG G+ G G GF G RG+ G G GP GPPGP
Sbjct: 1027 GLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPA 1086
Query: 570 MEQMGGRRGGRGGPG 584
G RG G G
Sbjct: 1087 GSP--GERGPAGAAG 1099
Score = 73.9 bits (180), Expect = 4e-13
Identities = 168/664 (25%), Positives = 217/664 (32%), Gaps = 161/664 (24%)
Query: 26 TQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTATYGQTAYATSYGQPPTGYTTPTAPQA 85
T+G + Y + Y Y P D+ + T + T T AP
Sbjct: 264 TEGDGEGETYYYEYPY--YEDPEDLGKEPTPSKKPVEAAKETTEVPEELTPTPTEAAPMP 321
Query: 86 YSQPVQG----YGTGAYDTTTATVTTTQASYAAQSAYGT------QPAYPAYGQQ-PAAT 134
+ G G G YD + T + Y YG QP P G + P +T
Sbjct: 322 ETSEGAGKEEDVGIGDYDYVPSEDYYTPSPYD-DLTYGEGEENPDQPTDPGAGAEIPTST 380
Query: 135 APTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQA 194
A TS SS + + + + + + +Y PTS P + G
Sbjct: 381 ADTSNSSNPAPPPGEGADDLEGEFTEETIRNLDENYYDP----YYDPTSSPSEIG----- 431
Query: 195 PSQYSQQSSSY----GQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGG 250
P + Q + Y G + Q ++ G G GP + GP
Sbjct: 432 PGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPP-------- 483
Query: 251 FDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPP-----------VDPD 299
G G G +G GERG +PG P G D GPP D
Sbjct: 484 ---------GTMGPTGQVGDPGERGPPGRPGLP---GADGLPGPPGTMLMLPFRFGGGGD 531
Query: 300 EDSDNSAIYVQGLNDSVTLDDLADFFK-QCGVVKMNKRTGQ--PMIHIYLDKETGK--PK 354
S + Q L + G + + R G P L E G P+
Sbjct: 532 AGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQ 591
Query: 355 GDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRG--------GLPPRE 406
G V P K G D AR P +G GLP +
Sbjct: 592 GPRGVQGPPGPAGKPGRRGRAGSDG---------ARGMPGQTGPKGDRGFDGLAGLPGEK 642
Query: 407 GRGMPPPLRGGPGGPGGPG--GPMGRMGGRG-----GDRGGFPPRGP---------RGSR 450
G P G PG PG G G G +G RG G RG P+GP G
Sbjct: 643 GHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMD 702
Query: 451 GNPSGGGNV--QHRAG-DWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPP-------- 499
G P GNV Q G Q NPG P P+G + PP
Sbjct: 703 GQPGPKGNVGPQGEPGPPGQQGNPGAQG-------------LPGPQGAIGPPGEKGPLGK 749
Query: 500 --------FPPPGGDRGRGGPGGMRGGRG-----GLMDRGGPGGM-----FRGGRG--GD 539
P G G+ GP G +GG+G G + GP G+ RG +G G+
Sbjct: 750 PGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGE 809
Query: 540 RG-----GFRGGRGM--DRGGFG--GGR----------RGGPGGPPGPLMEQMGGRRGGR 580
+G GF+G G+ DRG G G R RGGP G PGPL G +G
Sbjct: 810 KGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPP--GEKGKL 867
Query: 581 GGPG 584
G PG
Sbjct: 868 GVPG 871
Score = 72.8 bits (177), Expect = 9e-13
Identities = 118/456 (25%), Positives = 152/456 (33%), Gaps = 118/456 (25%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS----QAPSQYSQQSSSYGQQSSFRQD 214
G+P GQQ +GQ+ G + P +P G P ++ GQ
Sbjct: 1198 GEPGPRGQQGLFGQK---GDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPP 1254
Query: 215 HP----SSMGVYGQES--GGFSGPGENRSMSGPDNRGR----GRGG-----FDRGGMSRG 259
P + G G + GG PG P G G GG +RG
Sbjct: 1255 GPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGES 1314
Query: 260 GRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLD 319
G G G G G G G P G D GPP +P + +G D
Sbjct: 1315 GPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKG-------D 1367
Query: 320 DLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDF 379
D +TG P TG+P PP A E G+
Sbjct: 1368 DGEP-----------GQTGSP-------GPTGEPGPSGPPGKRGPP-GPAGPEGRQGE-- 1406
Query: 380 QGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPP--LRGGPG-----------GPGGPGG 426
+G+K + L + PP + G + P+ G P P LRG PG GP GP G
Sbjct: 1407 KGAKGEAGL--EGPPGKT--GPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPG 1462
Query: 427 PMGRMG--GRGGDRGGFPPRGPRGSRGNPS-----GGGNVQHRAGDWQCPNPGCGNQNFA 479
PMG G G GD G P+G +G+P G Q GD P P
Sbjct: 1463 PMGPPGLPGLKGDSG------PKGEKGHPGLIGLIGPPGEQGEKGDRGLPGP-------- 1508
Query: 480 WRTECNQCKAPKPEGFLPPPFPP--PGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRG 537
PK E + P P P G G GP G +G +G GP G
Sbjct: 1509 -----QGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGS----SGPTG------- 1552
Query: 538 GDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQM 573
+G G GP GPPG +++ +
Sbjct: 1553 ------------PKGEAGHPGPPGPPGPPGEVIQPL 1576
Score = 69.3 bits (168), Expect = 9e-12
Identities = 118/438 (26%), Positives = 145/438 (33%), Gaps = 90/438 (20%)
Query: 216 PSSMGVYGQESG----GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSA 271
P G G++ G G GP R +GP RG + G G GG G G
Sbjct: 888 PGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPK--GNSGGDGPAGPP 945
Query: 272 GERGGFNKPGGPMD-EGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGV 330
GERG N P GP GP GPP P +D L Q G
Sbjct: 946 GERGP-NGPQGPTGFPGPK---GPPGPPGKDG------------------LPGHPGQRGE 983
Query: 331 VKMNKRTGQPMIHIYLDKE--TGK--PKGDATVSYEDPPTAKAAVEWFDGKD-FQGSKLK 385
+TG P + + TG+ P G+ P + + GK+ +G
Sbjct: 984 TGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGP 1043
Query: 386 VSLARKKPPMNSMRG--------------GLPPREGRGMPPPLRGGPG--GPGGPGGPMG 429
L K P +RG GL EG PP G PG GP G GP+G
Sbjct: 1044 AGLPGKDGPPG-LRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPIG 1102
Query: 430 RMGGRGGDRGGFPPRGPRGSRGN--PSGGGNVQHRAGDWQCPNPGC--------GNQNFA 479
+ GR G +G P G +G+ G P G G P P G++
Sbjct: 1103 -IPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEI 1161
Query: 480 WRTECNQCKAPKPEGFLPPPFPPPG-----------------------GDRGRGGPGGMR 516
K K E P P P G G +G GP G
Sbjct: 1162 GEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFP 1221
Query: 517 GGRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGMDRGGFGGGRRGGPGGPPGPLME 571
G G + +G PG G GD G G G RG G +G PGG P
Sbjct: 1222 GPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAV 1281
Query: 572 QMGGRRGGRGGPGKMDKG 589
G G G PG +G
Sbjct: 1282 GEKGEPGEAGEPGLPGEG 1299
Score = 59.7 bits (143), Expect = 7e-09
Identities = 75/232 (32%), Positives = 90/232 (38%), Gaps = 34/232 (14%)
Query: 374 FDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGG 433
F G GSK + A++ ++ G P L G PG G PG GG
Sbjct: 526 FGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGS-----GG 580
Query: 434 RGGDRGGFPPRGPRGSRGNPSGGGNVQHRA---GDWQCPNPGC----GNQNFAWRT---- 482
G+ G P+GPRG +G P G R D PG G++ F
Sbjct: 581 LKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPG 640
Query: 483 ECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG- 541
E P P G PP PP GD G G G G RG L GP G+ G G G
Sbjct: 641 EKGHRGDPGPSG---PPGPP--GDDGERGDDGEVGPRG-LPGEPGPRGLL--GPKGPPGP 692
Query: 542 -GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQ-------MGGRRGGRGGPGK 585
G G GMD G G GP G PGP +Q + G +G G PG+
Sbjct: 693 PGPPGVTGMD-GQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGE 743
>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
Length = 1745
Score = 86.7 bits (213), Expect = 6e-17
Identities = 132/477 (27%), Positives = 164/477 (34%), Gaps = 83/477 (17%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFR------ 212
G P G G Q G P YP G + ++ Q + F
Sbjct: 683 GHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDV 742
Query: 213 -----QDHPSSMGVYGQESG-GFSGPGENRSMSGPDNRGRGRGGFDRGGM-SRGGRGGGR 265
Q P + G G++ G G GP +G G+ GR G +
Sbjct: 743 GLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPK 802
Query: 266 GG------MGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLD 319
G +G GE+G K G P EG + GPP E A G V D
Sbjct: 803 GSIGFPGPLGPIGEKGKSGKTGQPGLEG---ERGPPGSRGERGQPGATGQPGPKGDVGQD 859
Query: 320 DLADFFKQCGVVKMNKRTG-----QPMIHIYLDKETGKP--KGDATVSYEDPPTAKAAVE 372
+ G+ + G P H D G P +G+ + P A V
Sbjct: 860 GAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVL 919
Query: 373 WFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGR-------GMPPPL--------RGG 417
GK + L PP GLP EGR G P PL RG
Sbjct: 920 GPQGKTGEVGPLG-ERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGF 978
Query: 418 PGGPGGPG--GPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGN 475
PG GGPG GP G G +G P GP G+ G+P G + G PG
Sbjct: 979 PGPKGGPGDPGPTGLKGDKG-------PPGPVGANGSPGERGPLGPAGG---IGLPG--- 1025
Query: 476 QNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGG 535
Q + P G P G+RG GP G G G L G PG G
Sbjct: 1026 ----------QSGSEGPVG--PAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSG 1073
Query: 536 RGGDRG-----GFRGGRGMDRGGFG-GGRRG--GPGGPPGPLMEQMGGRRGGRGGPG 584
GD+G G +G +G D+G G G+ G GP G PGP G +G RG PG
Sbjct: 1074 EEGDKGDVGAPGHKGSKG-DKGDAGPPGQPGIRGPAGHPGP--PGADGAQGRRGPPG 1127
Score = 81.3 bits (199), Expect = 2e-15
Identities = 124/462 (26%), Positives = 160/462 (34%), Gaps = 87/462 (18%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSS--YGQQSSFRQDHP 216
G G Q G+ G++ P P G P ++ + G ++ P
Sbjct: 914 GPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQG-LPGLEGREGAKGELGPPGPLGKEGP 972
Query: 217 SSMGVYGQESGGFSGPGEN--RSMSGPD-----NRGRGRGG--FDRGGMSRGGRGGGRGG 267
+ + + GG PG + GP N G G GG+ G+ G G
Sbjct: 973 AGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGP 1032
Query: 268 MGSAGERG--GFNKPGGPMDE----GPDLDLGPP--VDPD-EDSDNSAIYVQGLNDSVTL 318
+G AG++G G P GP + GP LGPP P E+ D + G S
Sbjct: 1033 VGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGS--- 1089
Query: 319 DDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKD 378
K +K P G+P + PP A A
Sbjct: 1090 -------------KGDKGDAGP---------PGQPGIRGPAGHPGPPGADGA-------- 1119
Query: 379 FQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG--GPMGRMGGRG- 435
QG + L +K + +RG + G PP L+G PG PG G G +G MG G
Sbjct: 1120 -QGRRGPPGLFGQKGD-DGVRGFV----GVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGA 1173
Query: 436 -GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEG 494
G RG P+GP GS G P G V PG + + E P P G
Sbjct: 1174 PGPRG---PQGPTGSEGTPGLPGGVGQ---------PGAVGE----KGERGDAGDPGPPG 1217
Query: 495 FLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGM 549
P P P GD G G G G G +G PG G G G G G G+
Sbjct: 1218 --APGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGV 1275
Query: 550 DRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEH 591
G +G PG GP G G G PGK H
Sbjct: 1276 SGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGH 1317
Score = 79.3 bits (194), Expect = 9e-15
Identities = 104/385 (27%), Positives = 134/385 (34%), Gaps = 102/385 (26%)
Query: 216 PSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERG 275
P G+ G+E G GP R + GP G R G G G G G G+RG
Sbjct: 496 PGHPGLKGEE--GAEGPQGPRGLQGPHGPPGRVGKMGRPGAD--GARGLPGDTGPKGDRG 551
Query: 276 GFNKPGGPMDEGPDLD---LGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVK 332
PG P ++G D +G P P ED + A G
Sbjct: 552 FDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTG------------------ 593
Query: 333 MNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK 392
+ G+P P+G PT + V DG G+K V +
Sbjct: 594 ---QAGEP-----------GPRGLLGPRGSPGPTGRPGVTGIDGAP--GAKGNVGPPGEP 637
Query: 393 PPM----NSMRGGLPPREGRGMPPPLRGGPGGPGGPG-----GPMGRMGGRGGDRGGFPP 443
P N GLP +G P +G PG PG PG GP+G G G P
Sbjct: 638 GPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEG-------P 690
Query: 444 RGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPP 503
G +G++G P G PP +P P
Sbjct: 691 TGEKGAQGPPGSAG---------------------------------------PPGYPGP 711
Query: 504 GGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMD--RGGFGGGRR 559
G +G G G++G +G + G PG G GD+G G G RG D G G +
Sbjct: 712 RGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQ 771
Query: 560 GGPGGPPGPLMEQMGGRRGGRGGPG 584
G GPPG E+ G+ G G PG
Sbjct: 772 AGEEGPPGSAGEK--GKLGVPGLPG 794
Score = 73.6 bits (179), Expect = 5e-13
Identities = 122/465 (26%), Positives = 155/465 (33%), Gaps = 115/465 (24%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G+P GQQ ++G Q G Q P + G +P
Sbjct: 635 GEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGP----------------------PGNPGI 672
Query: 219 MGVYGQESG----GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGER 274
G+ G + G GP + GP G G+ G G G RG G GE+
Sbjct: 673 PGLPGSDGPLGHPGHEGPTGEKGAQGPPGSA-GPPGYP-GPRGVKGTSGNRGLQGEKGEK 730
Query: 275 GGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMN 334
G PG D G D G P P ++ +G Q G
Sbjct: 731 GEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKG---------------QAGQAGEE 775
Query: 335 KRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPP 394
G E GK Y P K ++ + G K K
Sbjct: 776 GPPGSA-------GEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGK--------- 819
Query: 395 MNSMRGGLPPREGRGMPPPLRGGPGGPG-----GPGGPMGRMGGRG--GDRG-------- 439
S + G P EG PP RG G PG GP G +G+ G G G++G
Sbjct: 820 --SGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPP 877
Query: 440 GFP-PRGPRGSRGNPSGGGNVQHRA-----GDWQCPNPG--CGNQNFAWRTECNQCKAPK 491
GFP P+GP G +G G+ R G P P G Q
Sbjct: 878 GFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVG-------- 929
Query: 492 PEGFLPPPFPP-PGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMD 550
P G PP PP P G++G G G G +G L G PG + + G G RG
Sbjct: 930 PLGERGPPGPPGPPGEQGLPGLEGREGAKGEL---GPPGPLGKEGPAGLRGF-------- 978
Query: 551 RGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQER 595
G +GGPG P GP G +G +G PG + ER
Sbjct: 979 -----PGPKGGPGDP-GPT-----GLKGDKGPPGPVGANGSPGER 1012
Score = 71.2 bits (173), Expect = 2e-12
Identities = 124/465 (26%), Positives = 157/465 (33%), Gaps = 103/465 (22%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G+ G + G + S G + P Q G + P+ + + G Q R+ P
Sbjct: 1073 GEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGI--RGPAGHPGPPGADGAQG--RRGPPGL 1128
Query: 219 MGVYGQESG----GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGER 274
G G + G GP + + GP +G G D G M G G RG G G
Sbjct: 1129 FGQKGDDGVRGFVGVIGPPGLQGLPGPPGE-KGEVG-DVGSMGPHGAPGPRGPQGPTGSE 1186
Query: 275 GGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMN 334
G PGG G + G D + A + G +
Sbjct: 1187 GTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIG----------------- 1229
Query: 335 KRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK-P 393
KGD+ S P K DG +GS L P
Sbjct: 1230 ------------------EKGDSGPSGAAGPPGKKGPPGEDGA--KGSVGPTGLPGDLGP 1269
Query: 394 PMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG-----------GPMGRMG--GRGGDRG- 439
P + G+ G P GGPG PG G GP G MG GR G++G
Sbjct: 1270 PGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGA 1329
Query: 440 -------GFPPR-GPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPK 491
G P R GP G+RG P G R PG AP
Sbjct: 1330 KGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGL-------------LGAP- 1375
Query: 492 PEGFLPPPFP-PPGGDRGRGGPGGMRGGRG--GLMDRGGPGGMFRGGRGGDRG--GFRGG 546
G + PP P P G G G G +G +G GL+ GP G G GD+G G +G
Sbjct: 1376 --GQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPG--EAGEKGDQGLPGVQGP 1431
Query: 547 RGM-----DRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKM 586
G G G GP G GPL G++G +G PG M
Sbjct: 1432 PGPKGDPGPPGPIGSLGHPGPPGVAGPL-----GQKGSKGSPGSM 1471
Score = 67.8 bits (164), Expect = 3e-11
Identities = 102/360 (28%), Positives = 125/360 (34%), Gaps = 68/360 (18%)
Query: 264 GRGGMGSAGERGGFNK-------PGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSV 316
G G G+ GE K PG P +G GPP P D GL
Sbjct: 371 GAGEKGAKGEPAVIEKGQQFEGPPGAPGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIP 430
Query: 317 TLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDG 376
+D + G P I + P A S++ PP + F
Sbjct: 431 GIDGIR---------------GPPGTVIMM------PFQFAGGSFKGPPVS------FQQ 463
Query: 377 KDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRG--------GPGGPGGPGGPM 428
Q + L+ K PP G P G P L+G GP G GP GP
Sbjct: 464 AQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPP 523
Query: 429 GRMG--GRGGDRG--GFP----PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAW 480
GR+G GR G G G P P+G RG G P G R PG ++
Sbjct: 524 GRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGER 583
Query: 481 RTE-----CNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGG 535
E Q P P G L P P G GR G G+ G G + G PG G
Sbjct: 584 GAEGPPGPTGQAGEPGPRGLLGPRGSP--GPTGRPGVTGIDGAPGAKGNVGPPGEPGPPG 641
Query: 536 RGGDRG--GFRGGRGMDRGGFGGGRRGGPG-----GPPGPL----MEQMGGRRGGRGGPG 584
+ G+ G G G +G+ G G PG G GPL E G +G +G PG
Sbjct: 642 QQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPG 701
Score = 64.7 bits (156), Expect = 2e-10
Identities = 73/224 (32%), Positives = 88/224 (39%), Gaps = 39/224 (17%)
Query: 393 PPMNSMRGGLPPREG-RGMPPPL-----RGGPGGPGGPG-----GPMGRMG-----GRGG 436
PP + G P +G RG+P RG G PG PG G G +G G G
Sbjct: 522 PPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDG 581
Query: 437 DRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFL 496
+RG P GP G G P G + R PG + AP +G +
Sbjct: 582 ERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGID----------GAPGAKGNV 631
Query: 497 PPPFP--PPG-----GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGR 547
PP PPG G +G GP G+ G G G PG G G G G G
Sbjct: 632 GPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPT 691
Query: 548 GMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPG-KMDKGE 590
G ++G G GP G PGP + G G RG G K +KGE
Sbjct: 692 G-EKGAQGPPGSAGPPGYPGP--RGVKGTSGNRGLQGEKGEKGE 732
Score = 64.3 bits (155), Expect = 3e-10
Identities = 113/436 (25%), Positives = 139/436 (31%), Gaps = 89/436 (20%)
Query: 155 QNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQD 214
Q G P G+ G +G P TGS + G Q
Sbjct: 1150 QGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGS-----------EGTPGLPGGVGQ- 1197
Query: 215 HPSSMGVYGQES-GGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGE 273
P ++G G+ G GP + GP +G D G G G +G G G
Sbjct: 1198 -PGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKG--DSGPSGAAGPPGKKGPPGEDGA 1254
Query: 274 RGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSV-TLDDLADFFKQCGVVK 332
+G G P D LGPP DP V G++ S D D
Sbjct: 1255 KGSVGPTGLPGD------LGPPGDPG---------VSGIDGSPGEKGDPGD--------- 1290
Query: 333 MNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK 392
G P G P PP + + +G K A+ +
Sbjct: 1291 ----VGGP----------GPPGASGEPGAPGPPGKRGPSGHMGREGREGEKG----AKGE 1332
Query: 393 PPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG-----GRGGDRGGFPPRGPR 447
P + G P RG PP R GP G G GP+G G G+ G G P G
Sbjct: 1333 PGPDGPPGRTGPMGARG--PPGRVGPEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLP 1390
Query: 448 GSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDR 507
G +G+ G H PG + Q P P+G P P P G
Sbjct: 1391 GLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQ-GPPGPKG--DPGPPGPIGSL 1447
Query: 508 GRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPG 567
G GP G+ G G +G PG M G GD G GP GPPG
Sbjct: 1448 GHPGPPGVAGPLGQKGSKGSPGSM---GPRGDTG-----------------PAGPPGPPG 1487
Query: 568 PLMEQMGGRRGGRGGP 583
E G RR R P
Sbjct: 1488 APAELHGLRRRRRFVP 1503
Score = 40.0 bits (92), Expect = 0.006
Identities = 61/205 (29%), Positives = 77/205 (37%), Gaps = 78/205 (38%)
Query: 441 FPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPF 500
FP G +G++G P+ V + ++ P PG AP P+G + P
Sbjct: 369 FPGAGEKGAKGEPA----VIEKGQQFEGP-PG----------------APGPQGVVGPSG 407
Query: 501 P--PPG--GDRGRGGPGGMRGGRGGLMDRGGP-----------GGMFRG----------- 534
P PPG GD G GP G+ G G RG P GG F+G
Sbjct: 408 PPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFAGGSFKGPPVSFQQAQAQ 467
Query: 535 --------------------GRGGDRG--GFRGGRGMDRGGFGGGRRG--GPGGPPGPLM 570
GR G G G G +G + G RG GP GPPG +
Sbjct: 468 AVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPG-RV 526
Query: 571 EQMG--GRRGGRGGPG----KMDKG 589
+MG G G RG PG K D+G
Sbjct: 527 GKMGRPGADGARGLPGDTGPKGDRG 551
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 84.3 bits (207), Expect = 3e-16
Identities = 109/375 (29%), Positives = 130/375 (34%), Gaps = 46/375 (12%)
Query: 232 PGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLD 291
PG+ + + GP +G G RG RG +G G+ G RG +PG P + GP
Sbjct: 109 PGDIKDIVGPKGPPGPQGPAGEQG-PRGDRGD-KGEKGAPGPRGRDGEPGTPGNPGPPGP 166
Query: 292 LGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQ-----PMIHIYL 346
GPP P + +A G ++ L G + G P
Sbjct: 167 PGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGN 226
Query: 347 DKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRG-----G 401
E G+P + PP G D + K + R P RG G
Sbjct: 227 PGEPGEPGVSGPMGPRGPPGPPGK----PGDDGEAGKPGKAGERGPPGPQGARGFPGTPG 282
Query: 402 LPPREGRGMPPPLRGGPGGPGGPGGPMGRMG--GRGGDRGGFPPRGPRGSRGNPSGGGNV 459
LP +G P L G G G PG G G G G G PRG G RG G
Sbjct: 283 LPGVKGHRGYPGLDGAKGEAGAPG-VKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAA 341
Query: 460 QHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPP-FPPPGGDRGRGGPGGMRGG 518
R D Q P P P P G P FP G +G GP G RG
Sbjct: 342 GARGNDGQ-PGPA---------------GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGP 385
Query: 519 RGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGMDRGGFGGGRRG--GPGGPPGPLME 571
G RG PG G G G G G +G G G GP GPPGP
Sbjct: 386 EGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGP-QG 444
Query: 572 QMG--GRRGGRGGPG 584
G G +G G PG
Sbjct: 445 ATGPLGPKGQTGEPG 459
Score = 81.6 bits (200), Expect = 2e-15
Identities = 147/513 (28%), Positives = 192/513 (37%), Gaps = 101/513 (19%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G P + G+ G + G Q P P GS P+ S + G + + +
Sbjct: 369 GAPGAKGEAGPTGARGPEGAQGPRGEPGTPGS--PGPAGASGNPGTDGIPGA--KGSAGA 424
Query: 219 MGVYGQESGGFSGPGENRSMSGPDN-------RGR----GRGGF--DRGGMSRGGRGGGR 265
G+ G + GF GP R GP +G+ G GF ++G G G +
Sbjct: 425 PGIAG--APGFPGP---RGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQ 479
Query: 266 GGMGSAGE---RGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLA 322
G G AGE RG +PGG GP + G P + + +G LA
Sbjct: 480 GAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLA 539
Query: 323 DFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGS 382
G R G+P + TG+P GDA P K G+D +
Sbjct: 540 G---PKGANGDPGRPGEPGLPGARGL-TGRP-GDAG------PQGKVGPSGAPGEDGRPG 588
Query: 383 KLKVSLARKKPPMNSMRG-----GLPPREG-RGMP--PPLRGGPG--------GPGGPGG 426
AR +P + G G P + G +G+P P LRG PG GP GP G
Sbjct: 589 PPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAG 648
Query: 427 PMGRMGGRG--GDRG--GFP-PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWR 481
P G G +G G G G P P GP G G P G V AG P G + F
Sbjct: 649 PAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQG-VPGEAGAPGLVGPR-GERGFPGE 706
Query: 482 TE---CNQCKAPK----------PEGFLPPPFPP-----PG-----GDRGRGGPGGMRGG 518
+ P+ P+G P PP PG G+RG G G +G
Sbjct: 707 RGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGD 766
Query: 519 RGGLMDRGGPGGMFR-GGRG--------GDRG--GFRGGRGMDRGGFGGGRRGGPG---- 563
RG + ++G G + GGRG G G G +G G G RG PG
Sbjct: 767 RGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGE 826
Query: 564 -GPPGPLMEQMGGRRGGRGGPG-KMDKGEHRQE 594
GPPGP G G G PG K ++GE Q+
Sbjct: 827 TGPPGP--AGFAGPPGADGQPGAKGEQGEAGQK 857
Score = 81.3 bits (199), Expect = 2e-15
Identities = 118/424 (27%), Positives = 149/424 (35%), Gaps = 64/424 (15%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSS-FRQDHPS 217
GQP + G+Q GQ+ G P P Q P+ + + G Q P
Sbjct: 843 GQPGAKGEQGEAGQKGDAGAPGPQG--PSGAPGPQGPTGVTGPKGARGAQGPPGATGFPG 900
Query: 218 SMGVYGQE-SGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGG 276
+ G G S G GP SG D RG D G R G G +G G GE+G
Sbjct: 901 AAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARG--DSGPPGRAGEPGLQGPAGPPGEKG- 957
Query: 277 FNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKR 336
+PG D+GP GPP QGL + L + G +
Sbjct: 958 --EPG---DDGPSGAEGPPGP------------QGLAGQRGIVGLPGQRGERGFPGLPGP 1000
Query: 337 TGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMN 396
+G+P GK +G S + P G + + + S PP
Sbjct: 1001 SGEP----------GK-QGAPGASGDRGPPGPVGPPGLTGPAGEPGR-EGSPGADGPPGR 1048
Query: 397 SMRGGLPPREGRGMPPPLRGGPGGPGGPG--GPMGRMGGRG--GDRGGFPPRGPRGSRG- 451
G+ G G PG PG PG GP G+ G RG G +G P GP G+RG
Sbjct: 1049 DGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGI 1108
Query: 452 -NPSGGGNVQHRAGDWQCPNPG----CGNQNFAWRTECNQCKAPKPEGFLPPPFPPPG-- 504
P G + AG+ PG G++ F P + P P G
Sbjct: 1109 QGPQGPRGDKGEAGE-----PGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPR 1163
Query: 505 GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGG 564
G G GP G G G G PG GR G+ G G G GP G
Sbjct: 1164 GPPGPVGPSGKDGANGIPGPIGPPGPR---GRSGETG--------PAGPPGNPGPPGPPG 1212
Query: 565 PPGP 568
PPGP
Sbjct: 1213 PPGP 1216
Score = 80.9 bits (198), Expect = 3e-15
Identities = 127/492 (25%), Positives = 158/492 (32%), Gaps = 72/492 (14%)
Query: 131 PAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGS 190
P P S Q Q G+ + G G + G++ P P + G
Sbjct: 725 PGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGG 784
Query: 191 YS-QAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRG 249
P + + G++ P+ +G PGE R +GP G
Sbjct: 785 RGLTGPIGPPGPAGANGEKGEVGPPGPAG------SAGARGAPGE-RGETGPP----GPA 833
Query: 250 GFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYV 309
GF G G+ G +G G AG++G PG +GP GP A
Sbjct: 834 GF-AGPPGADGQPGAKGEQGEAGQKGDAGAPG---PQGPSGAPGPQGPTGVTGPKGARGA 889
Query: 310 QGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGK-------PKGDATVSYE 362
QG + A + G N G P K+ K P G A
Sbjct: 890 QGPPGATGFPGAAG---RVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGL 946
Query: 363 DPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRG-----GLPPREGRGMPPPLRGG 417
P + G D A P + G GLP + G P L G
Sbjct: 947 QGPAGPPGEKGEPGDDGPSG------AEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGP 1000
Query: 418 PGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQN 477
G PG G P G GDRG P GP G G G D G
Sbjct: 1001 SGEPGKQGAP-----GASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVK 1055
Query: 478 FAWRTECNQCKAPKPEGFLPPPFPPPGG------DRGRGG------PGGMRGGRGGLMDR 525
R E AP G PP P P G DRG G P G G RG +
Sbjct: 1056 -GDRGETGAVGAPGAPG--PPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQ 1112
Query: 526 GGPGGMFRGGRGGDRG-----GFRGGRGM--------DRGGFGGGRRGGPGGPPGPLMEQ 572
G G G G+RG GF G +G+ D+G G GP GPPGP+
Sbjct: 1113 GPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPV--G 1170
Query: 573 MGGRRGGRGGPG 584
G+ G G PG
Sbjct: 1171 PSGKDGANGIPG 1182
Score = 78.6 bits (192), Expect = 2e-14
Identities = 130/461 (28%), Positives = 156/461 (33%), Gaps = 78/461 (16%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G P + G G G+ P+ P + G P Q + + P
Sbjct: 555 GLPGARGLTGRPGDAGPQGKVGPSGAPGEDGR----PGPPGPQGA---------RGQPGV 601
Query: 219 MGVYGQESGGFSGPGENRSMSGPDNRG-RGRGGFDRGGMSRGGRGGGRGGMGSAGERGGF 277
MG G + G PG+ P G RG G D G G G G AGERG
Sbjct: 602 MGFPGPK-GANGEPGKAGEKGLPGAPGLRGLPGKD----GETGAAGPPGPAGPAGERGEQ 656
Query: 278 NKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRT 337
PG +G GPP + + D G V F + G
Sbjct: 657 GAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQ 716
Query: 338 GQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNS 397
G + G P D P A + G + +A K
Sbjct: 717 GPRGL-------PGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD 769
Query: 398 M--RG--GLPPREG-RGMPPPLRGGPGGPGG---------PGGPMGRMGGRG--GDRGGF 441
+ +G G P ++G RG+ P+ GP GP G P GP G G RG G+RG
Sbjct: 770 VGEKGPEGAPGKDGGRGLTGPI--GPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGET 827
Query: 442 PPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGC-GNQNFAWRTECNQCKAPKPEGFLPPPF 500
P GP G G P G PG G Q A + AP P+G P
Sbjct: 828 GPPGPAGFAGPPGADGQ------------PGAKGEQGEAGQK--GDAGAPGPQG--PSGA 871
Query: 501 PPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGMD----- 550
P P G G GP G RG +G G PG R G G G G G G D
Sbjct: 872 PGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGA 931
Query: 551 RGGFG-GGRRG-----GPGGPPGPLMEQ-MGGRRGGRGGPG 584
RG G GR G GP GPPG E G G G PG
Sbjct: 932 RGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPG 972
Score = 77.8 bits (190), Expect = 3e-14
Identities = 133/494 (26%), Positives = 170/494 (34%), Gaps = 82/494 (16%)
Query: 125 PAYGQQPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY 184
P + P A + + Q + T G P G + G G +
Sbjct: 365 PGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGA 424
Query: 185 PPQTGSYS----QAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESG-GFSGPGENRSMS 239
P G+ + P + G + + P G G++ G GP +
Sbjct: 425 PGIAGAPGFPGPRGPPGPQGATGPLGPKG--QTGEPGIAGFKGEQGPKGEPGPAGPQGAP 482
Query: 240 GPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPD 299
GP G + G G GG+G G G PG G D GP P
Sbjct: 483 GP-----------AGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPG 531
Query: 300 EDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATV 359
E + +G N R G+P + TG+P GDA
Sbjct: 532 ERGPSGLAGPKGANGD------------------PGRPGEPGLP-GARGLTGRP-GDA-- 569
Query: 360 SYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRG-----GLPPREG-RGMP-- 411
P K G+D + AR +P + G G P + G +G+P
Sbjct: 570 ----GPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGA 625
Query: 412 PPLRGGPG--------GPGGPGGPMGRMGGRG--GDRG--GFP-PRGPRGSRGNPSGGGN 458
P LRG PG GP GP GP G G +G G G G P P GP G G P G
Sbjct: 626 PGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKP-GDQG 684
Query: 459 VQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPK-PEGFLPPPFPPPGGDRGRGGPGGMRG 517
V AG P G + F + + P G P P G +G GP G G
Sbjct: 685 VPGEAGAPGLVGPR-GERGFPGERGSPGAQGLQGPRGL--PGTPGTDGPKGASGPAGPPG 741
Query: 518 GRGGLMDRGGPGGMFRGGRG-----GDRG--GFRGGRGMDRGGFGGGRRGGPGGPPGPLM 570
+G +G PG RG G GDRG G +G G G GG GP GPPGP
Sbjct: 742 AQGPPGLQGMPGE--RGAAGIAGPKGDRGDVGEKGPEGAP-GKDGGRGLTGPIGPPGP-- 796
Query: 571 EQMGGRRGGRGGPG 584
G +G G PG
Sbjct: 797 AGANGEKGEVGPPG 810
Score = 77.4 bits (189), Expect = 3e-14
Identities = 120/461 (26%), Positives = 150/461 (32%), Gaps = 95/461 (20%)
Query: 159 GQPSSYGQQSSYGQ-QSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQD-HP 216
GQP GQ+ G + G + P PQ + Q P G +D P
Sbjct: 98 GQPGPKGQKGEPGDIKDIVGPKGPPG--PQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEP 155
Query: 217 SSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDR--------------GGMSRGGRG 262
+ G G G GP + G + + GGFD G M G
Sbjct: 156 GTPGNPGPP--GPPGPPGPPGLGG-NFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPP 212
Query: 263 GGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLA 322
G G G G +G +PG P GP GPP P + D+ G
Sbjct: 213 GPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPG----------- 261
Query: 323 DFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPP-----TAKAAVEWFDGK 377
+ G E G P + P DG
Sbjct: 262 -------------KAG----------ERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGA 298
Query: 378 DFQGSKLKVSLARKKPPMNSMRG-----GLPPREGRGMPPPLRGGPG-----GPGGPGGP 427
+ V P N G GLP GR P G G GP GP GP
Sbjct: 299 KGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGP 358
Query: 428 MGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECN 485
+G GG G G G GP G+RG P G + G P P + N
Sbjct: 359 VGPAGGPGFPGAPGAKGEAGPTGARG-PEGAQGPRGEPGTPGSPGPAGASGN-------- 409
Query: 486 QCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GF 543
P +G P G G G G G RG +G G + G+ G+ G GF
Sbjct: 410 ----PGTDGI--PGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGF 463
Query: 544 RGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPG 584
+G ++G G GP G PGP E+ G+RG RG PG
Sbjct: 464 KG----EQGPKGEPGPAGPQGAPGPAGEE--GKRGARGEPG 498
Score = 73.9 bits (180), Expect = 4e-13
Identities = 70/196 (35%), Positives = 80/196 (40%), Gaps = 14/196 (7%)
Query: 404 PREGRGMPPPLRG--GPGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNV 459
P+ +G P ++ GP GP GP GP G G RG GD+G GPRG G P GN
Sbjct: 102 PKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNP 161
Query: 460 QHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPE-GFLPPPFPPPGGDRGRGGPGGMRGG 518
PG G A KA + G + P P G RG GP G G
Sbjct: 162 GPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPM-GPRGPPGPAGAPGP 220
Query: 519 RGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGR 576
+G + G PG G G RG G G G D G G + G GPPGP G
Sbjct: 221 QGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPG-DDGEAGKPGKAGERGPPGP-----QGA 274
Query: 577 RGGRGGPGKMDKGEHR 592
RG G PG HR
Sbjct: 275 RGFPGTPGLPGVKGHR 290
Score = 73.6 bits (179), Expect = 5e-13
Identities = 120/447 (26%), Positives = 143/447 (31%), Gaps = 60/447 (13%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYP--PQTGSYSQAPSQYSQQSSSYGQQSSFRQDHP 216
G P G+ G + G P P P G A + G Q Q
Sbjct: 144 GAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPM 203
Query: 217 SSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGG 276
MG G G PG P G G G G G G AG+ G
Sbjct: 204 GPMGPRGPP-GPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGK 262
Query: 277 FNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKR 336
+ G P +G G P P V+G LD + G +
Sbjct: 263 AGERGPPGPQGARGFPGTPGLPG---------VKGHRGYPGLDGAKG---EAGAPGVKGE 310
Query: 337 TGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMN 396
+G P + + P G + E T A G D Q P
Sbjct: 311 SGSPG-----ENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQ------------PGPA 353
Query: 397 SMRGGLPPREGRGMP-PPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNP-- 453
G + P G G P P G GP G GP G G R G+ G GP G+ GNP
Sbjct: 354 GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPR-GEPGTPGSPGPAGASGNPGT 412
Query: 454 ------SGGGNVQHRAGDWQCPNP--GCGNQNFAWRT-ECNQCKAPKPEGFL----PPPF 500
G AG P P G Q Q P GF P
Sbjct: 413 DGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGE 472
Query: 501 PPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRG 560
P P G +G GP G G RG RG PGG+ G G+RG G RG G +G
Sbjct: 473 PGPAGPQGAPGPAGEEGKRGA---RGEPGGVGPIGPPGERGA-PGNRGFPGQDGLAGPKG 528
Query: 561 GPG--GPPGPLMEQMGGRRGGRGGPGK 585
PG GP G + G +G G PG+
Sbjct: 529 APGERGPSG-----LAGPKGANGDPGR 550
Score = 73.6 bits (179), Expect = 5e-13
Identities = 115/436 (26%), Positives = 145/436 (33%), Gaps = 95/436 (21%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQ-YSQQSSSYGQQSSFRQDHPS 217
G P G + G G + YP G+ +A + +S S G+ S P
Sbjct: 267 GPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGS-----PG 321
Query: 218 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRG-GRGGGRGGMGSAGERGG 276
MG G PGE R +GP RG + G + G G GG G G G
Sbjct: 322 PMGPRGL-------PGE-RGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGA 373
Query: 277 FNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKR 336
+ G GP+ GP +P G + + D + G +
Sbjct: 374 KGEAGPTGARGPEGAQGPRGEPGTPGSPGPA---GASGNPGTDGIPGAKGSAGAPGIAGA 430
Query: 337 TGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMN 396
G P P+G PP + A K G +P +
Sbjct: 431 PGFP-----------GPRG--------PPGPQGATGPLGPKGQTG----------EPGIA 461
Query: 397 SMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPS 454
+G P+ G P GP GP G GP G G RG G+ GG P GP G RG P
Sbjct: 462 GFKGEQGPK---GEP-----GPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAP- 512
Query: 455 GGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPP-PGGDRGRGGPG 513
GN+ F P +G P P G G GP
Sbjct: 513 -------------------GNRGF-----------PGQDGLAGPKGAPGERGPSGLAGPK 542
Query: 514 GMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPG----PL 569
G G G + G PG GR GD G G+ G G R GP GP G P
Sbjct: 543 GANGDPGRPGEPGLPGARGLTGRPGDAG--PQGKVGPSGAPGEDGRPGPPGPQGARGQPG 600
Query: 570 MEQMGGRRGGRGGPGK 585
+ G +G G PGK
Sbjct: 601 VMGFPGPKGANGEPGK 616
Score = 50.8 bits (120), Expect = 3e-06
Identities = 61/195 (31%), Positives = 72/195 (36%), Gaps = 45/195 (23%)
Query: 417 GPGGPGGPGGPMGRMGGRGGDRGGFPPRGP------RGSRGNPSGGGNVQHRAGDWQCPN 470
G GP G G G + G +G P+GP RG RG+ G R D +
Sbjct: 98 GQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGT 157
Query: 471 PGCGNQNFAWRTECNQCKAPKPEGFLPPPFPP-----------PGGDRGRGGP--GGMRG 517
PG P P G PP PP G D GG G M+G
Sbjct: 158 PG----------------NPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQG 201
Query: 518 GRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRR 577
G + RG PG G G + GF+G G + G G GP GPPGP G+
Sbjct: 202 PMGPMGPRGPPG---PAGAPGPQ-GFQGNPG-EPGEPGVSGPMGPRGPPGP-----PGKP 251
Query: 578 GGRGGPGKMDKGEHR 592
G G GK K R
Sbjct: 252 GDDGEAGKPGKAGER 266
Score = 37.0 bits (84), Expect = 0.052
Identities = 38/152 (25%), Positives = 52/152 (34%), Gaps = 19/152 (12%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS----QAPSQYSQQSSSYGQQSSFRQD 214
G P G G + G Q P G+ Q P ++ G++ +
Sbjct: 1074 GSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGL--KG 1131
Query: 215 HPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRG-------- 266
H G+ G G GP ++ SGP RG G + G+ G G
Sbjct: 1132 HRGFTGLQGLP--GPPGPSGDQGASGPAGPSGPRG--PPGPVGPSGKDGANGIPGPIGPP 1187
Query: 267 -GMGSAGERGGFNKPGGPMDEGPDLDLGPPVD 297
G +GE G PG P GP GP +D
Sbjct: 1188 GPRGRSGETGPAGPPGNPGPPGPPGPPGPGID 1219
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 84.3 bits (207), Expect = 3e-16
Identities = 109/375 (29%), Positives = 130/375 (34%), Gaps = 46/375 (12%)
Query: 232 PGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLD 291
PG+ + + GP +G G RG RG +G G+ G RG +PG P + GP
Sbjct: 40 PGDIKDIVGPKGPPGPQGPAGEQG-PRGDRGD-KGEKGAPGPRGRDGEPGTPGNPGPPGP 97
Query: 292 LGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQ-----PMIHIYL 346
GPP P + +A G ++ L G + G P
Sbjct: 98 PGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGN 157
Query: 347 DKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRG-----G 401
E G+P + PP G D + K + R P RG G
Sbjct: 158 PGEPGEPGVSGPMGPRGPPGPPGK----PGDDGEAGKPGKAGERGPPGPQGARGFPGTPG 213
Query: 402 LPPREGRGMPPPLRGGPGGPGGPGGPMGRMG--GRGGDRGGFPPRGPRGSRGNPSGGGNV 459
LP +G P L G G G PG G G G G G PRG G RG G
Sbjct: 214 LPGVKGHRGYPGLDGAKGEAGAPG-VKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAA 272
Query: 460 QHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPP-FPPPGGDRGRGGPGGMRGG 518
R D Q P P P P G P FP G +G GP G RG
Sbjct: 273 GARGNDGQ-PGPA---------------GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGP 316
Query: 519 RGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGMDRGGFGGGRRG--GPGGPPGPLME 571
G RG PG G G G G G +G G G GP GPPGP
Sbjct: 317 EGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGP-QG 375
Query: 572 QMG--GRRGGRGGPG 584
G G +G G PG
Sbjct: 376 ATGPLGPKGQTGEPG 390
Score = 81.6 bits (200), Expect = 2e-15
Identities = 147/513 (28%), Positives = 192/513 (37%), Gaps = 101/513 (19%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G P + G+ G + G Q P P GS P+ S + G + + +
Sbjct: 300 GAPGAKGEAGPTGARGPEGAQGPRGEPGTPGS--PGPAGASGNPGTDGIPGA--KGSAGA 355
Query: 219 MGVYGQESGGFSGPGENRSMSGPDN-------RGR----GRGGF--DRGGMSRGGRGGGR 265
G+ G + GF GP R GP +G+ G GF ++G G G +
Sbjct: 356 PGIAG--APGFPGP---RGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQ 410
Query: 266 GGMGSAGE---RGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLA 322
G G AGE RG +PGG GP + G P + + +G LA
Sbjct: 411 GAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLA 470
Query: 323 DFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGS 382
G R G+P + TG+P GDA P K G+D +
Sbjct: 471 G---PKGANGDPGRPGEPGLPGARGL-TGRP-GDAG------PQGKVGPSGAPGEDGRPG 519
Query: 383 KLKVSLARKKPPMNSMRG-----GLPPREG-RGMP--PPLRGGPG--------GPGGPGG 426
AR +P + G G P + G +G+P P LRG PG GP GP G
Sbjct: 520 PPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAG 579
Query: 427 PMGRMGGRG--GDRG--GFP-PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWR 481
P G G +G G G G P P GP G G P G V AG P G + F
Sbjct: 580 PAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQG-VPGEAGAPGLVGPR-GERGFPGE 637
Query: 482 TE---CNQCKAPK----------PEGFLPPPFPP-----PG-----GDRGRGGPGGMRGG 518
+ P+ P+G P PP PG G+RG G G +G
Sbjct: 638 RGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGD 697
Query: 519 RGGLMDRGGPGGMFR-GGRG--------GDRG--GFRGGRGMDRGGFGGGRRGGPG---- 563
RG + ++G G + GGRG G G G +G G G RG PG
Sbjct: 698 RGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGE 757
Query: 564 -GPPGPLMEQMGGRRGGRGGPG-KMDKGEHRQE 594
GPPGP G G G PG K ++GE Q+
Sbjct: 758 TGPPGP--AGFAGPPGADGQPGAKGEQGEAGQK 788
Score = 81.3 bits (199), Expect = 2e-15
Identities = 118/424 (27%), Positives = 149/424 (35%), Gaps = 64/424 (15%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSS-FRQDHPS 217
GQP + G+Q GQ+ G P P Q P+ + + G Q P
Sbjct: 774 GQPGAKGEQGEAGQKGDAGAPGPQG--PSGAPGPQGPTGVTGPKGARGAQGPPGATGFPG 831
Query: 218 SMGVYGQE-SGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGG 276
+ G G S G GP SG D RG D G R G G +G G GE+G
Sbjct: 832 AAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARG--DSGPPGRAGEPGLQGPAGPPGEKG- 888
Query: 277 FNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKR 336
+PG D+GP GPP QGL + L + G +
Sbjct: 889 --EPG---DDGPSGAEGPPGP------------QGLAGQRGIVGLPGQRGERGFPGLPGP 931
Query: 337 TGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMN 396
+G+P GK +G S + P G + + + S PP
Sbjct: 932 SGEP----------GK-QGAPGASGDRGPPGPVGPPGLTGPAGEPGR-EGSPGADGPPGR 979
Query: 397 SMRGGLPPREGRGMPPPLRGGPGGPGGPG--GPMGRMGGRG--GDRGGFPPRGPRGSRG- 451
G+ G G PG PG PG GP G+ G RG G +G P GP G+RG
Sbjct: 980 DGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGI 1039
Query: 452 -NPSGGGNVQHRAGDWQCPNPG----CGNQNFAWRTECNQCKAPKPEGFLPPPFPPPG-- 504
P G + AG+ PG G++ F P + P P G
Sbjct: 1040 QGPQGPRGDKGEAGE-----PGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPR 1094
Query: 505 GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGG 564
G G GP G G G G PG GR G+ G G G GP G
Sbjct: 1095 GPPGPVGPSGKDGANGIPGPIGPPGPR---GRSGETG--------PAGPPGNPGPPGPPG 1143
Query: 565 PPGP 568
PPGP
Sbjct: 1144 PPGP 1147
Score = 80.9 bits (198), Expect = 3e-15
Identities = 127/492 (25%), Positives = 158/492 (32%), Gaps = 72/492 (14%)
Query: 131 PAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGS 190
P P S Q Q G+ + G G + G++ P P + G
Sbjct: 656 PGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGG 715
Query: 191 YS-QAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRG 249
P + + G++ P+ +G PGE R +GP G
Sbjct: 716 RGLTGPIGPPGPAGANGEKGEVGPPGPAG------SAGARGAPGE-RGETGPP----GPA 764
Query: 250 GFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYV 309
GF G G+ G +G G AG++G PG +GP GP A
Sbjct: 765 GF-AGPPGADGQPGAKGEQGEAGQKGDAGAPG---PQGPSGAPGPQGPTGVTGPKGARGA 820
Query: 310 QGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGK-------PKGDATVSYE 362
QG + A + G N G P K+ K P G A
Sbjct: 821 QGPPGATGFPGAAG---RVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGL 877
Query: 363 DPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRG-----GLPPREGRGMPPPLRGG 417
P + G D A P + G GLP + G P L G
Sbjct: 878 QGPAGPPGEKGEPGDDGPSG------AEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGP 931
Query: 418 PGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQN 477
G PG G P G GDRG P GP G G G D G
Sbjct: 932 SGEPGKQGAP-----GASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVK 986
Query: 478 FAWRTECNQCKAPKPEGFLPPPFPPPGG------DRGRGG------PGGMRGGRGGLMDR 525
R E AP G PP P P G DRG G P G G RG +
Sbjct: 987 -GDRGETGAVGAPGAPG--PPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQ 1043
Query: 526 GGPGGMFRGGRGGDRG-----GFRGGRGM--------DRGGFGGGRRGGPGGPPGPLMEQ 572
G G G G+RG GF G +G+ D+G G GP GPPGP+
Sbjct: 1044 GPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPV--G 1101
Query: 573 MGGRRGGRGGPG 584
G+ G G PG
Sbjct: 1102 PSGKDGANGIPG 1113
Score = 78.6 bits (192), Expect = 2e-14
Identities = 130/461 (28%), Positives = 156/461 (33%), Gaps = 78/461 (16%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G P + G G G+ P+ P + G P Q + + P
Sbjct: 486 GLPGARGLTGRPGDAGPQGKVGPSGAPGEDGR----PGPPGPQGA---------RGQPGV 532
Query: 219 MGVYGQESGGFSGPGENRSMSGPDNRG-RGRGGFDRGGMSRGGRGGGRGGMGSAGERGGF 277
MG G + G PG+ P G RG G D G G G G AGERG
Sbjct: 533 MGFPGPK-GANGEPGKAGEKGLPGAPGLRGLPGKD----GETGAAGPPGPAGPAGERGEQ 587
Query: 278 NKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRT 337
PG +G GPP + + D G V F + G
Sbjct: 588 GAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQ 647
Query: 338 GQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNS 397
G + G P D P A + G + +A K
Sbjct: 648 GPRGL-------PGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGD 700
Query: 398 M--RG--GLPPREG-RGMPPPLRGGPGGPGG---------PGGPMGRMGGRG--GDRGGF 441
+ +G G P ++G RG+ P+ GP GP G P GP G G RG G+RG
Sbjct: 701 VGEKGPEGAPGKDGGRGLTGPI--GPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGET 758
Query: 442 PPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGC-GNQNFAWRTECNQCKAPKPEGFLPPPF 500
P GP G G P G PG G Q A + AP P+G P
Sbjct: 759 GPPGPAGFAGPPGADGQ------------PGAKGEQGEAGQK--GDAGAPGPQG--PSGA 802
Query: 501 PPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGMD----- 550
P P G G GP G RG +G G PG R G G G G G G D
Sbjct: 803 PGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGA 862
Query: 551 RGGFG-GGRRG-----GPGGPPGPLMEQ-MGGRRGGRGGPG 584
RG G GR G GP GPPG E G G G PG
Sbjct: 863 RGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPG 903
Score = 78.2 bits (191), Expect = 2e-14
Identities = 114/402 (28%), Positives = 137/402 (34%), Gaps = 68/402 (16%)
Query: 231 GPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDL 290
GP GP RG DRG G G RG G G G PG P
Sbjct: 48 GPKGPPGPQGPAGEQGPRG--DRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPP------- 98
Query: 291 DLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQ-----PMIHIY 345
GPP P + +A G ++ L G + G P
Sbjct: 99 --GPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQG 156
Query: 346 LDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRG----- 400
E G+P + PP G D + K + R P RG
Sbjct: 157 NPGEPGEPGVSGPMGPRGPPGPPGK----PGDDGEAGKPGKAGERGPPGPQGARGFPGTP 212
Query: 401 GLPPREG-RGMP-----------PPLRGGPGGPGGPGGPMGRMGGRG--GDRGGFPPRGP 446
GLP +G RG P P ++G G PG G P G MG RG G+RG P G
Sbjct: 213 GLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSP-GPMGPRGLPGERGRTGPAGA 271
Query: 447 RGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPP--PG 504
G+RGN G PG A + E A PEG P P PG
Sbjct: 272 AGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGA-KGEAGPTGARGPEGAQGPRGEPGTPG 330
Query: 505 -----------------GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----G 542
G +G G G+ G G RG PG G G +G G
Sbjct: 331 SPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPG 390
Query: 543 FRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPG 584
G +G ++G G GP G PGP E+ G+RG RG PG
Sbjct: 391 IAGFKG-EQGPKGEPGPAGPQGAPGPAGEE--GKRGARGEPG 429
Score = 77.8 bits (190), Expect = 3e-14
Identities = 133/494 (26%), Positives = 170/494 (34%), Gaps = 82/494 (16%)
Query: 125 PAYGQQPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY 184
P + P A + + Q + T G P G + G G +
Sbjct: 296 PGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGA 355
Query: 185 PPQTGSYS----QAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESG-GFSGPGENRSMS 239
P G+ + P + G + + P G G++ G GP +
Sbjct: 356 PGIAGAPGFPGPRGPPGPQGATGPLGPKG--QTGEPGIAGFKGEQGPKGEPGPAGPQGAP 413
Query: 240 GPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPD 299
GP G + G G GG+G G G PG G D GP P
Sbjct: 414 GP-----------AGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPG 462
Query: 300 EDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATV 359
E + +G N R G+P + TG+P GDA
Sbjct: 463 ERGPSGLAGPKGANGD------------------PGRPGEPGLP-GARGLTGRP-GDA-- 500
Query: 360 SYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRG-----GLPPREG-RGMP-- 411
P K G+D + AR +P + G G P + G +G+P
Sbjct: 501 ----GPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGA 556
Query: 412 PPLRGGPG--------GPGGPGGPMGRMGGRG--GDRG--GFP-PRGPRGSRGNPSGGGN 458
P LRG PG GP GP GP G G +G G G G P P GP G G P G
Sbjct: 557 PGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKP-GDQG 615
Query: 459 VQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPK-PEGFLPPPFPPPGGDRGRGGPGGMRG 517
V AG P G + F + + P G P P G +G GP G G
Sbjct: 616 VPGEAGAPGLVGPR-GERGFPGERGSPGAQGLQGPRGL--PGTPGTDGPKGASGPAGPPG 672
Query: 518 GRGGLMDRGGPGGMFRGGRG-----GDRG--GFRGGRGMDRGGFGGGRRGGPGGPPGPLM 570
+G +G PG RG G GDRG G +G G G GG GP GPPGP
Sbjct: 673 AQGPPGLQGMPGE--RGAAGIAGPKGDRGDVGEKGPEGAP-GKDGGRGLTGPIGPPGP-- 727
Query: 571 EQMGGRRGGRGGPG 584
G +G G PG
Sbjct: 728 AGANGEKGEVGPPG 741
Score = 73.9 bits (180), Expect = 4e-13
Identities = 70/196 (35%), Positives = 80/196 (40%), Gaps = 14/196 (7%)
Query: 404 PREGRGMPPPLRG--GPGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNV 459
P+ +G P ++ GP GP GP GP G G RG GD+G GPRG G P GN
Sbjct: 33 PKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNP 92
Query: 460 QHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPE-GFLPPPFPPPGGDRGRGGPGGMRGG 518
PG G A KA + G + P P G RG GP G G
Sbjct: 93 GPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPM-GPRGPPGPAGAPGP 151
Query: 519 RGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGR 576
+G + G PG G G RG G G G D G G + G GPPGP G
Sbjct: 152 QGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPG-DDGEAGKPGKAGERGPPGP-----QGA 205
Query: 577 RGGRGGPGKMDKGEHR 592
RG G PG HR
Sbjct: 206 RGFPGTPGLPGVKGHR 221
Score = 73.6 bits (179), Expect = 5e-13
Identities = 120/447 (26%), Positives = 143/447 (31%), Gaps = 60/447 (13%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYP--PQTGSYSQAPSQYSQQSSSYGQQSSFRQDHP 216
G P G+ G + G P P P G A + G Q Q
Sbjct: 75 GAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPM 134
Query: 217 SSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGG 276
MG G G PG P G G G G G G AG+ G
Sbjct: 135 GPMGPRGPP-GPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGK 193
Query: 277 FNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKR 336
+ G P +G G P P V+G LD + G +
Sbjct: 194 AGERGPPGPQGARGFPGTPGLPG---------VKGHRGYPGLDGAKG---EAGAPGVKGE 241
Query: 337 TGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMN 396
+G P + + P G + E T A G D Q P
Sbjct: 242 SGSPG-----ENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQ------------PGPA 284
Query: 397 SMRGGLPPREGRGMP-PPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNP-- 453
G + P G G P P G GP G GP G G R G+ G GP G+ GNP
Sbjct: 285 GPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPR-GEPGTPGSPGPAGASGNPGT 343
Query: 454 ------SGGGNVQHRAGDWQCPNP--GCGNQNFAWRT-ECNQCKAPKPEGFL----PPPF 500
G AG P P G Q Q P GF P
Sbjct: 344 DGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGE 403
Query: 501 PPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRG 560
P P G +G GP G G RG RG PGG+ G G+RG G RG G +G
Sbjct: 404 PGPAGPQGAPGPAGEEGKRGA---RGEPGGVGPIGPPGERGA-PGNRGFPGQDGLAGPKG 459
Query: 561 GPG--GPPGPLMEQMGGRRGGRGGPGK 585
PG GP G + G +G G PG+
Sbjct: 460 APGERGPSG-----LAGPKGANGDPGR 481
Score = 73.6 bits (179), Expect = 5e-13
Identities = 115/436 (26%), Positives = 145/436 (33%), Gaps = 95/436 (21%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQ-YSQQSSSYGQQSSFRQDHPS 217
G P G + G G + YP G+ +A + +S S G+ S P
Sbjct: 198 GPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGS-----PG 252
Query: 218 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRG-GRGGGRGGMGSAGERGG 276
MG G PGE R +GP RG + G + G G GG G G G
Sbjct: 253 PMGPRGL-------PGE-RGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGA 304
Query: 277 FNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKR 336
+ G GP+ GP +P G + + D + G +
Sbjct: 305 KGEAGPTGARGPEGAQGPRGEPGTPGSPGPA---GASGNPGTDGIPGAKGSAGAPGIAGA 361
Query: 337 TGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMN 396
G P P+G PP + A K G +P +
Sbjct: 362 PGFP-----------GPRG--------PPGPQGATGPLGPKGQTG----------EPGIA 392
Query: 397 SMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPS 454
+G P+ G P GP GP G GP G G RG G+ GG P GP G RG P
Sbjct: 393 GFKGEQGPK---GEP-----GPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAP- 443
Query: 455 GGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPP-PGGDRGRGGPG 513
GN+ F P +G P P G G GP
Sbjct: 444 -------------------GNRGF-----------PGQDGLAGPKGAPGERGPSGLAGPK 473
Query: 514 GMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPG----PL 569
G G G + G PG GR GD G G+ G G R GP GP G P
Sbjct: 474 GANGDPGRPGEPGLPGARGLTGRPGDAG--PQGKVGPSGAPGEDGRPGPPGPQGARGQPG 531
Query: 570 MEQMGGRRGGRGGPGK 585
+ G +G G PGK
Sbjct: 532 VMGFPGPKGANGEPGK 547
Score = 37.0 bits (84), Expect = 0.052
Identities = 38/152 (25%), Positives = 52/152 (34%), Gaps = 19/152 (12%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYS----QAPSQYSQQSSSYGQQSSFRQD 214
G P G G + G Q P G+ Q P ++ G++ +
Sbjct: 1005 GSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGL--KG 1062
Query: 215 HPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRG-------- 266
H G+ G G GP ++ SGP RG G + G+ G G
Sbjct: 1063 HRGFTGLQGLP--GPPGPSGDQGASGPAGPSGPRG--PPGPVGPSGKDGANGIPGPIGPP 1118
Query: 267 -GMGSAGERGGFNKPGGPMDEGPDLDLGPPVD 297
G +GE G PG P GP GP +D
Sbjct: 1119 GPRGRSGETGPAGPPGNPGPPGPPGPPGPGID 1150
>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
sapiens]
Length = 940
Score = 83.2 bits (204), Expect = 6e-16
Identities = 81/215 (37%), Positives = 83/215 (38%), Gaps = 41/215 (19%)
Query: 409 GMPPPLRG------GPGGP-------GGPG---GPMGR-MGGRGGDRGGFPPRGPRGSRG 451
G PPP RG GPG P GGPG GP R GGRGG+ PP RG+RG
Sbjct: 668 GPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGRGGRGGNEPPPPPPPFRGARG 727
Query: 452 NPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRG- 510
SGGG R G PG G P PGG G G
Sbjct: 728 GRSGGGPPNGRGG------PGGGMVGGGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGH 781
Query: 511 ----GPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRR--GGPGG 564
GPGG GG GG GPGG GG G R G GM G GGG R GPGG
Sbjct: 782 RPHEGPGGSMGGGGGHRPHEGPGGGISGG-SGHRPHEGPGGGM---GAGGGHRPHEGPGG 837
Query: 565 PPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRP 599
MGG G R G G H D P
Sbjct: 838 -------SMGGSGGHRPHEGPGHGGPHGHRPHDVP 865
Score = 72.0 bits (175), Expect = 1e-12
Identities = 71/206 (34%), Positives = 74/206 (35%), Gaps = 64/206 (31%)
Query: 411 PPPLRGG--PGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQC 468
P P+ G PGGPGGP G G GG P GP G G P G
Sbjct: 622 PGPIANGFPPGGPGGPKGMQHFPPGPGG-----PMPGPHGGPGGPVG------------- 663
Query: 469 PNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGG-MRGG--RGGLMDR 525
P+ L PP PP GGD GPG MRGG RGG
Sbjct: 664 ---------------------PR---LLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPG 699
Query: 526 GGPGGMFRGGRGGDR-----GGFRGGRGMDRGGFGGGRRGGPGG------------PPGP 568
GP RGGRGG+ FRG RG GG RGGPGG PG
Sbjct: 700 PGPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHRPHEGPGG 759
Query: 569 LMEQMGGRRGGRGGPGKMDKGEHRQE 594
M G R G G M G E
Sbjct: 760 GMGNSSGHRPHEGPGGGMGSGHRPHE 785
Score = 59.7 bits (143), Expect = 7e-09
Identities = 82/225 (36%), Positives = 90/225 (40%), Gaps = 60/225 (26%)
Query: 416 GGPGG-PGGPGGPM------GRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQH-RAGDWQ 467
GG GG P G GG MG G +G P+GP G GG NVQ
Sbjct: 540 GGSGGSPDGAGGSKLPPVLANLMGSMGAGKG---PQGPGG------GGINVQEILTSIMG 590
Query: 468 CPNPGCGNQNFAWRTECNQCKAP-KPEGFLPP-----PFPP--PGGDRGR----GGPGG- 514
PN + ++ K P G L P FPP PGG +G GPGG
Sbjct: 591 SPNSHPSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGP 650
Query: 515 MRGGRGGLMDRGGPGGMFRGG-----RGGD----------RGG-FRGGRGMDRGGF--GG 556
M G GG GGP G G RGGD RGG RGG G G + G
Sbjct: 651 MPGPHGG---PGGPVGPRLLGPPPPPRGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGR 707
Query: 557 GRRGG--PGGPPGPLMEQMGGRRG-----GRGGP--GKMDKGEHR 592
G RGG P PP P GGR G GRGGP G + G HR
Sbjct: 708 GGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGGGGHR 752
Score = 35.8 bits (81), Expect = 0.12
Identities = 37/102 (36%), Positives = 41/102 (40%), Gaps = 29/102 (28%)
Query: 228 GFSGPGENRSMSGPDNRGRG-RGGFD-----------RGGMSRGGRGGGRGG-----MGS 270
G GPG GP +RGRG RGG + RGG S GG GRGG +G
Sbjct: 694 GGPGPGP-----GPYHRGRGGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGGMVGG 748
Query: 271 AGER------GGF-NKPGGPMDEGPDLDLGPPVDPDEDSDNS 305
G R GG N G EGP +G P E S
Sbjct: 749 GGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGS 790
Score = 35.8 bits (81), Expect = 0.12
Identities = 24/76 (31%), Positives = 27/76 (35%)
Query: 209 SSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGM 268
SS + H G G GPG + G G GG GG G GGM
Sbjct: 764 SSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGM 823
Query: 269 GSAGERGGFNKPGGPM 284
G+ G PGG M
Sbjct: 824 GAGGGHRPHEGPGGSM 839
Score = 32.0 bits (71), Expect = 1.7
Identities = 27/75 (36%), Positives = 30/75 (40%), Gaps = 6/75 (8%)
Query: 218 SMGVYG----QESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGE 273
SMG G E G GP +R P +RG G RG G G GG G G
Sbjct: 838 SMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRGHDHRG-PPPHEHRGHDGPGHGGGGHRGH 896
Query: 274 RGGFNKPGGPMDEGP 288
GG + GG M P
Sbjct: 897 DGG-HSHGGDMSNRP 910
Score = 30.8 bits (68), Expect = 3.7
Identities = 23/62 (37%), Positives = 24/62 (38%), Gaps = 10/62 (16%)
Query: 227 GGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDE 286
GG SG +R GP GG GG R G G GS G GG GP
Sbjct: 805 GGISGGSGHRPHEGPG------GGMGAGGGHRPHEGPG----GSMGGSGGHRPHEGPGHG 854
Query: 287 GP 288
GP
Sbjct: 855 GP 856
Score = 29.6 bits (65), Expect = 8.3
Identities = 24/68 (35%), Positives = 26/68 (38%), Gaps = 2/68 (2%)
Query: 227 GGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPM-D 285
GG G G +R GP G GG GG GG G G GG GG
Sbjct: 774 GGGMGSG-HRPHEGPGGSMGGGGGHRPHEGPGGGISGGSGHRPHEGPGGGMGAGGGHRPH 832
Query: 286 EGPDLDLG 293
EGP +G
Sbjct: 833 EGPGGSMG 840
>gi|48762934 alpha 2 type I collagen [Homo sapiens]
Length = 1366
Score = 82.0 bits (201), Expect = 1e-15
Identities = 137/480 (28%), Positives = 159/480 (33%), Gaps = 95/480 (19%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G+P G + G + G P P +G + S+ R P S
Sbjct: 346 GEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGS-PGS 404
Query: 219 MGVYGQES-GGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGF 277
G+ G + G GP +R SGP RG GR G G MG G
Sbjct: 405 RGLPGADGRAGVMGPPGSRGASGPAGV--------RGPNGDAGRPGEPGLMGPRG----- 451
Query: 278 NKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRT 337
PG P + GP GP P D I G G T
Sbjct: 452 -LPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEP---------GNIGFPGPKGPT 501
Query: 338 GQP-----MIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKD-------FQGSKLK 385
G P H L G P D + PP V+ G+ FQG
Sbjct: 502 GDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPP-GPQGVQGGKGEQGPPGPPGFQGLPGP 560
Query: 386 VSLARK--KPPMNSMRG--GLP----PREGRGMPPPLRGGPG--------GPGGPGGPMG 429
A + KP + G GLP PR RG PP G G GP GP GP G
Sbjct: 561 SGPAGEVGKPGERGLHGEFGLPGPAGPRGERG-PPGESGAAGPTGPIGSRGPSGPPGPDG 619
Query: 430 RMGGRG--GDRGGFPPRGP------RGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWR 481
G G G G P GP RG+ G P G G + NPG R
Sbjct: 620 NKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGA----R 675
Query: 482 TECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRG-----GPGGMFRG-- 534
AP P G G+ G GP G G RG +RG GP G F G
Sbjct: 676 GAPGAVGAPGPAG-----ATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNG-FAGPA 729
Query: 535 ------GRGGDRG--GFRGGRGM--DRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPG 584
G G+RG G +G G+ G G GP GPPGP G RG G PG
Sbjct: 730 GAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGP-----AGSRGDGGPPG 784
Score = 82.0 bits (201), Expect = 1e-15
Identities = 113/384 (29%), Positives = 135/384 (35%), Gaps = 74/384 (19%)
Query: 228 GFSGPGENRSMSGPDNRGRGRGGFDRGG-------MSRGGRGGGRGGMGSAGERGGFNKP 280
G GP N GP +GG G G G G +G GERG +
Sbjct: 520 GAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEF 579
Query: 281 GGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQP 340
G P GP + GPP + I +G + D NK G+P
Sbjct: 580 GLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDG-------------NK--GEP 624
Query: 341 MIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRG 400
+ + T P G + + P + A GK +G +RG
Sbjct: 625 GVVGAVG--TAGPSGPSGL-----PGERGAAGIPGGKGEKGEP-------------GLRG 664
Query: 401 --GLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGN 458
G P R+G RG PG G PG P G G RG + G P GP G RG+P G
Sbjct: 665 EIGNPGRDGA------RGAPGAVGAPG-PAGATGDRG-EAGAAGPAGPAGPRGSPGERGE 716
Query: 459 VQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPE-GFLPPPFP-----------PPG-- 504
V + G Q A K PK E G + P P PPG
Sbjct: 717 VGPAGPNGFAGPAGAAGQPGAKGER--GAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPA 774
Query: 505 GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-----GFRGGRGMDRGGFGGGRR 559
G RG GGP GM G G G PG G G G G RG RG D+G G
Sbjct: 775 GSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRG-DQGPVGRTGE 833
Query: 560 GGPGGPPGPLMEQMGGRRGGRGGP 583
G GPPG E+ G GP
Sbjct: 834 VGAVGPPGFAGEKGPSGEAGTAGP 857
Score = 77.8 bits (190), Expect = 3e-14
Identities = 132/472 (27%), Positives = 163/472 (34%), Gaps = 87/472 (18%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQ-DHPS 217
G + G G Q G+Q P P G PS + + G++ + P
Sbjct: 526 GNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGL--PGPSGPAGEVGKPGERGLHGEFGLPG 583
Query: 218 SMGVYGQ-----ESG--GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGS 270
G G+ ESG G +GP +R SGP +G + G + G G G G
Sbjct: 584 PAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKG--EPGVVGAVGTAGPSGPSGL 641
Query: 271 AGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGV 330
GERG PGG ++G G +P D +G +V A G
Sbjct: 642 PGERGAAGIPGGKGEKGEPGLRGEIGNPGRDG------ARGAPGAVGAPGPAGATGDRGE 695
Query: 331 VKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLAR 390
G P G E A F G + A
Sbjct: 696 AGAAGPAG--------------PAGPRGSPGERGEVGPAGPNGFAGP---------AGAA 732
Query: 391 KKPPMNSMRGGLPPREGRGMPPPL----RGGPGGPGGPGGPMGRMGGRGGDRG--GFP-- 442
+P RG P+ G+ P GP GP GP GP G G GG G GFP
Sbjct: 733 GQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGD-GGPPGMTGFPGA 791
Query: 443 -----PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFL- 496
P GP G G P G AG P G+Q RT + A P GF
Sbjct: 792 AGRTGPPGPSGISGPPGPPGP----AGKEGLRGPR-GDQGPVGRT--GEVGAVGPPGFAG 844
Query: 497 ------------PPPFPPPGGDRGRGGPGGMRGGRG--GLMDRGG----PGGMFRGGRGG 538
PP P P G G G G+ G RG GL G PG + G G
Sbjct: 845 EKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPG 904
Query: 539 DRG--GFRGGRGMDRGGFGGGRRGGPG--GPPGPLMEQMGGRRGGRGGPGKM 586
RG G G G++ GR G PG GPPG + G +G RG PG +
Sbjct: 905 ARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPG--RDGQPGHKGERGYPGNI 954
Score = 72.4 bits (176), Expect = 1e-12
Identities = 123/451 (27%), Positives = 146/451 (32%), Gaps = 65/451 (14%)
Query: 165 GQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQD-HPSSMGVYG 223
G + G G Q P P + G A ++ G +D HP G G
Sbjct: 100 GPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGAR-----GPAGPPGKAGEDGHPGKPGRPG 154
Query: 224 QESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGP 283
+ G GP R G G GF +G G G +G G+ G +G +PG P
Sbjct: 155 ER--GVVGPQGARGFPGTP----GLPGF-KGIRGHNGLDGLKGQPGAPGVKG---EPGAP 204
Query: 284 MDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIH 343
+ G G P E A G S D G + G P
Sbjct: 205 GENGTPGQTGARGLPGERGRVGAPGPAGARGS---DGSVGPVGPAGPIGSAGPPGFP--- 258
Query: 344 IYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK----PPMNSMR 399
PKG+ P A G + +V L PP N
Sbjct: 259 -----GAPGPKGEIGAVGNAGPAGPA-----------GPRGEVGLPGLSGPVGPPGNPGA 302
Query: 400 GGLPPREGRGMPPPLRGGPG--GPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGG 457
GL +G P + G PG GP G GP+G G G RG GP GS+G SG
Sbjct: 303 NGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGA-RGLVGEPGPAGSKGE-SGNK 360
Query: 458 NVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPP-------------FPPPG 504
AG P P E P P G P P
Sbjct: 361 GEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPP 420
Query: 505 GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGF-RGGRGMDRGGFGGGRRGGPG 563
G RG GP G+RG G G PG M G G G G+ G G R GP
Sbjct: 421 GSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPI 480
Query: 564 GPPGPLMEQ----MGGRRGGRGGPGKM-DKG 589
GP G E G +G G PGK DKG
Sbjct: 481 GPAGARGEPGNIGFPGPKGPTGDPGKNGDKG 511
Score = 72.0 bits (175), Expect = 1e-12
Identities = 69/199 (34%), Positives = 81/199 (40%), Gaps = 34/199 (17%)
Query: 414 LRGGPGGPGGPGGPMGRMG--GRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNP 471
+R GP G GP G G G GR G+ G P GP G G P GGN A +
Sbjct: 30 VRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNF---AAQYDGKGV 86
Query: 472 GCGNQNFAW---RTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGP 528
G G R AP P+GF P P G+ G+ GP G RG G G
Sbjct: 87 GLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEP--GEPGQTGPAGARGPAGPPGKAGED 144
Query: 529 GGMFRGGRGGDRG-----------------GFRGGRGMDRGGFGG--GRRGGPG--GPPG 567
G + GR G+RG GF+G RG G G G+ G PG G PG
Sbjct: 145 GHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRG--HNGLDGLKGQPGAPGVKGEPG 202
Query: 568 -PLMEQMGGRRGGRGGPGK 585
P G+ G RG PG+
Sbjct: 203 APGENGTPGQTGARGLPGE 221
Score = 71.6 bits (174), Expect = 2e-12
Identities = 104/367 (28%), Positives = 129/367 (35%), Gaps = 52/367 (14%)
Query: 261 RGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDD 320
R G G G GERG PG ++GP GPP P Q V L
Sbjct: 31 RKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGP 90
Query: 321 LADFFKQCGVVKMNKRTGQ-----PMIHIYLDKETGKPKGDATVSYEDP--PTAKAAVEW 373
G++ G P E G+P P P KA +
Sbjct: 91 -----GPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDG 145
Query: 374 FDGKDFQGSKLKV---SLARKKPPMNSMRG--------GLPPREGRGMPPPLRGGPGGPG 422
GK + + V AR P + G GL +G+ P ++G PG PG
Sbjct: 146 HPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPG 205
Query: 423 GPGGPMGRMGGRG--GDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGC------- 473
G P G+ G RG G+RG GP G+RG+ G V PG
Sbjct: 206 ENGTP-GQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPK 264
Query: 474 GNQNFAWRTECNQCKAPKPEGFLP---PPFPPPG--------GDRGRGGPGGMRGGRGGL 522
G P+ E LP P PPG G +G G G+ G G
Sbjct: 265 GEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLP 324
Query: 523 MDRGGPGGMFRGGRGGDRG-----GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRR 577
RG PG + G G RG G G +G + G G GP GPPGP E+ G+R
Sbjct: 325 GPRGIPGPVGAAGATGARGLVGEPGPAGSKG-ESGNKGEPGSAGPQGPPGPSGEE--GKR 381
Query: 578 GGRGGPG 584
G G G
Sbjct: 382 GPNGEAG 388
Score = 71.6 bits (174), Expect = 2e-12
Identities = 131/444 (29%), Positives = 158/444 (35%), Gaps = 93/444 (20%)
Query: 216 PSSMGVYGQESGGFSGPGENRSMSGPDNRG-RGRGGF-----DRGGMSRGGRGGGRGGMG 269
P G GQ +G PGE + P G RG G G + G G G G
Sbjct: 204 PGENGTPGQ-TGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPG 262
Query: 270 SAGERGGFNK-----PGGPMDE----GPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDD 320
GE G P GP E G +GPP +P + A GL
Sbjct: 263 PKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPG 322
Query: 321 LADFFKQCGVVKMNKRTGQPMIHIYLDKETGKP-----------KGDATVSYEDPPTAKA 369
L G V TG + G+P KG+ + P +
Sbjct: 323 LPGPRGIPGPVGAAGATGARGL-------VGEPGPAGSKGESGNKGEPGSAGPQGPPGPS 375
Query: 370 AVEWFDGKDFQGSKLKVSLARKKPPMNSMRG-----GLPPREGRG--MPPPLRGGPGGPG 422
E G + + S PP +RG GLP +GR M PP G GP
Sbjct: 376 GEEGKRGPNGEAG----SAGPPGPP--GLRGSPGSRGLPGADGRAGVMGPPGSRGASGPA 429
Query: 423 GPGGPMGRMGGRGGDRGGFPPRGPRGSRGN--PSGGGNVQHRAGDWQCPNPGCGNQNFAW 480
G GP G GR G+ G PRG GS GN P+G G P P G
Sbjct: 430 GVRGPNGD-AGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGP-IGPAGA-- 485
Query: 481 RTECNQCKAPKPEGFLPPP----------------FPPPGGDRGRGGPGGMRGGRGGLMD 524
R E P P+G P P P G+ G GP G +G +GG +
Sbjct: 486 RGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGE 545
Query: 525 RGGPGGM-FRG--GRGGDRG--GFRGGRGMDRGGFG-------GGRRGGPG-----GPPG 567
+G PG F+G G G G G G RG+ G FG G RG PG GP G
Sbjct: 546 QGPPGPPGFQGLPGPSGPAGEVGKPGERGL-HGEFGLPGPAGPRGERGPPGESGAAGPTG 604
Query: 568 PLMEQMGGRRGGRGGPG-KMDKGE 590
P+ G RG G PG +KGE
Sbjct: 605 PI-----GSRGPSGPPGPDGNKGE 623
Score = 68.2 bits (165), Expect = 2e-11
Identities = 122/483 (25%), Positives = 152/483 (31%), Gaps = 93/483 (19%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G+P G +G G + P ++G+ + S + P
Sbjct: 568 GKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPT-GPIGSRGPSGPPGPDGNKGEPGV 626
Query: 219 MGVYGQE--SGGFSGPGENRSMSGPDNRG-RGRGGFDRGGMSRGGRGGGRGGMGSAGERG 275
+G G SG PGE + P +G +G G RG + GR G RG G+ G G
Sbjct: 627 VGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGL-RGEIGNPGRDGARGAPGAVGAPG 685
Query: 276 GFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNK 335
G + G GP + + G N G
Sbjct: 686 PAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPN---------------GFAGPAG 730
Query: 336 RTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPM 395
GQP ++ PKG+ V P A +G S PP
Sbjct: 731 AAGQPGAKG--ERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAG----SRGDGGPPG 784
Query: 396 NSMRGGLPPREGRGMPPPLRG--GPGGPGGPGGPMGRMGGRG--------GDRGGFPPRG 445
+ G P GR PP G GP GP GP G G G RG G+ G P G
Sbjct: 785 MT---GFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPG 841
Query: 446 PRGSRGNPSGGGNVQHRAGDWQCPNP--------------GCGNQNFAWRTECNQCKAPK 491
G +G PSG AG P P G + P
Sbjct: 842 FAGEKG-PSGEAGT---AGPPGTPGPQGLLGAPGILGLPGSRGERGLPG--VAGAVGEPG 895
Query: 492 PEGFLPPPFP--PPG-----------------GDRGRGGPGGMRGGRGGLMDRGGPGGMF 532
P G PP PPG G+ G GP G G G +RG PG +
Sbjct: 896 PLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIG 955
Query: 533 RGGRGGDRG--------GFRGGRGM--DRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGG 582
G G G G G RG G G GP GP GP G RG +G
Sbjct: 956 PVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGP-----QGIRGDKGE 1010
Query: 583 PGK 585
PG+
Sbjct: 1011 PGE 1013
Score = 67.8 bits (164), Expect = 3e-11
Identities = 123/444 (27%), Positives = 157/444 (35%), Gaps = 82/444 (18%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
GQP + G++ + G + G PT P + P+ + S G P
Sbjct: 733 GQPGAKGERGAKGPKGENGVVGPTG--PVGAAGPAGPNGPPGPAGSRGDGGP-----PGM 785
Query: 219 MGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFN 278
G G + G +GP +SGP G + G+ RG RG +G +G GE G
Sbjct: 786 TGFPG--AAGRTGPPGPSGISGPPGPPGPAG---KEGL-RGPRGD-QGPVGRTGEVGAVG 838
Query: 279 KPGGPMDEGPDLDLG---PPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNK 335
PG ++GP + G PP P QGL + + L + G+ +
Sbjct: 839 PPGFAGEKGPSGEAGTAGPPGTPGP---------QGLLGAPGILGLPGSRGERGLPGVAG 889
Query: 336 RTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPM 395
G+P P G A PP A+ G+ + R P
Sbjct: 890 AVGEP-----------GPLGIA-----GPPGARGPPGAVGSPGVNGAPGEAG--RDGNPG 931
Query: 396 NSM---RGGLPPREG-RGMP----PPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPR 447
N R G P +G RG P P G GP GP GP G+ G R G+ G P GP
Sbjct: 932 NDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNR-GETGPSGPVGPA 990
Query: 448 GSRGNPSGGGNVQHRAGDWQCPN-------PGCGNQNFAWRTECNQCKAPKPEGFLPPPF 500
G+ G P G Q GD P PG N +G P
Sbjct: 991 GAVG-PRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGL-------------QGL--PGI 1034
Query: 501 PPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMDRGGFGGGR 558
GD+G G G G RG G G R G G G G RG +G G
Sbjct: 1035 AGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQ----GPAG 1090
Query: 559 RGGPGGPPGPLMEQMGGRRGGRGG 582
GP GPPGP GG G G
Sbjct: 1091 PPGPPGPPGPPGVSGGGYDFGYDG 1114
Score = 65.5 bits (158), Expect = 1e-10
Identities = 96/373 (25%), Positives = 116/373 (31%), Gaps = 75/373 (20%)
Query: 242 DNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGP------- 294
D +G G G G M G G G G G +G +PG P GP GP
Sbjct: 82 DGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKA 141
Query: 295 -----PVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKE 349
P P + + QG L F G ++ GQP
Sbjct: 142 GEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQP--------- 192
Query: 350 TGKP--KGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREG 407
G P KG+ E+ + G+ + + AR G P
Sbjct: 193 -GAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGS 251
Query: 408 RGMPPPLRGGPG-----------GPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGG 456
G PP G PG GP GP GP G +G G GP G GNP
Sbjct: 252 AG-PPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPG-------LSGPVGPPGNPGAN 303
Query: 457 GNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRG-----G 511
G + PG P P G +P P G RG G
Sbjct: 304 GLTGAKGA---AGLPGVAGAP----------GLPGPRG-IPGPVGAAGATGARGLVGEPG 349
Query: 512 PGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLME 571
P G +G G + G G G G+ G RG G GP GPPG
Sbjct: 350 PAGSKGESGNKGEPGSAGPQGPPGPSGEEG--------KRGPNGEAGSAGPPGPPG---- 397
Query: 572 QMGGRRGGRGGPG 584
+ G G RG PG
Sbjct: 398 -LRGSPGSRGLPG 409
Score = 62.4 bits (150), Expect = 1e-09
Identities = 124/472 (26%), Positives = 151/472 (31%), Gaps = 130/472 (27%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQA-PSQYSQQSSSYGQQSSFRQDHPS 217
G + G + G G P P + G A P+ ++ + + GQ
Sbjct: 685 GPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQP--------- 735
Query: 218 SMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGF 277
G G+ G GP + GP G + G G G G AG RG
Sbjct: 736 --GAKGER--GAKGPKGENGVVGPT-----------GPVGAAGPAGPNGPPGPAGSRGDG 780
Query: 278 NKPG-----------GPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFK 326
PG GP GP GPP P +G V
Sbjct: 781 GPPGMTGFPGAAGRTGP--PGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTG------ 832
Query: 327 QCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKV 386
+ G V G+ P G+A + PP G L
Sbjct: 833 EVGAVGPPGFAGEK-----------GPSGEAGTA--GPPGTPGPQGLLGAPGILG--LPG 877
Query: 387 SLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG-----GPMGRMGGRGGD---- 437
S + P + G P G PP RG PG G PG G GR G G D
Sbjct: 878 SRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPG 937
Query: 438 RGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLP 497
R G P G +G RG P G V AP P G
Sbjct: 938 RDGQP--GHKGERGYPGNIGPV-------------------------GAAGAPGPHG--- 967
Query: 498 PPFPPPG--GDRGRGGPGGMRGGRGGLMDRG--GPGGMFRGGRG-----GDRG--GFRGG 546
P P G G+RG GP G G G + RG GP G+ RG +G G RG G +G
Sbjct: 968 -PVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGI-RGDKGEPGEKGPRGLPGLKGH 1025
Query: 547 RGM-----------DRGGFGG-GRRG--GPGGPPGPLMEQMGGRRGGRGGPG 584
G+ D+G G G G GP GP GP G+ G G PG
Sbjct: 1026 NGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGP-----AGKDGRTGHPG 1072
Score = 34.7 bits (78), Expect = 0.26
Identities = 70/315 (22%), Positives = 95/315 (30%), Gaps = 51/315 (16%)
Query: 125 PAYGQQPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY 184
P + + + + T Q G P S G++ G + G+ P
Sbjct: 840 PGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGI 899
Query: 185 PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNR 244
G+ P + + R +P + G G++ PG P N
Sbjct: 900 AGPPGARGP-PGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQ----PGHKGERGYPGNI 954
Query: 245 GR-GRGGFD--RGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDED 301
G G G G + G+ G RG G +G G G GP G +P E
Sbjct: 955 GPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEK 1014
Query: 302 SDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSY 361
++G N L +A G G P+G A
Sbjct: 1015 GPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAG--------------PRGPA---- 1056
Query: 362 EDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGP 421
P+ A GKD R P G + P RG P GP GP
Sbjct: 1057 --GPSGPA------GKD----------GRTGHP-----GTVGPAGIRG--PQGHQGPAGP 1091
Query: 422 GGPGGPMGRMGGRGG 436
GP GP G G GG
Sbjct: 1092 PGPPGPPGPPGVSGG 1106
>gi|153252068 testes-specific heterogenous nuclear ribonucleoprotein
G-T [Homo sapiens]
Length = 392
Score = 82.0 bits (201), Expect = 1e-15
Identities = 96/316 (30%), Positives = 117/316 (37%), Gaps = 73/316 (23%)
Query: 347 DKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPRE 406
D+ET K +G A V++E P AKAA +GK G +KV+ A KP S R G PP
Sbjct: 42 DRETNKSRGFAFVTFESPADAKAAARDMNGKSLDGKAIKVAQA-TKPAFESSRRGPPPPR 100
Query: 407 GRGMPPPLRGGPGGPGGPGGPMGRMGGRGG--DRGGF-------------------PPR- 444
RG P LRG GG GGP R RGG D GG+ PPR
Sbjct: 101 SRGRPRFLRGTRGGGGGP----RRSPSRGGPDDDGGYTADFDLRPSRAPMPMKRGPPPRR 156
Query: 445 -GPRGSRGNPSG-----GGNVQHRA------------------GDWQCPNPGCGNQNFAW 480
GP R PSG GG ++ RA + P G ++ ++
Sbjct: 157 VGPPPKRAAPSGPARSSGGGMRGRALAVRGRDGYSGPPRREPLPPRRDPYLGPRDEGYSS 216
Query: 481 RTECNQCKAPKPEGFLPPPFP---------------PPGGDRGRGGPGGMRGGRGGLMDR 525
R + +P GF P P P G R G GG G + R
Sbjct: 217 RDGYSSRDYREPRGFAPSPGEYTHRDYGHSSVRDDCPLRGYSDRDGYGGRDRDYGDHLSR 276
Query: 526 GGPGGMFRGGRGGDRGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGK 585
G F G+ G GRG GGGR G GGR G+
Sbjct: 277 GSHREPFES--YGELRGAAPGRGTPPSYGGGGRYEEYRGYSPDAYS--GGRDSYSSSYGR 332
Query: 586 MD---KGEHRQERRDR 598
D +G HR R DR
Sbjct: 333 SDRYSRGRHRVGRPDR 348
Score = 29.6 bits (65), Expect = 8.3
Identities = 34/184 (18%), Positives = 61/184 (33%), Gaps = 32/184 (17%)
Query: 13 AAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTATYGQTAYATSYGQ 72
+++ GYS+ + +G+A + Y + YG ++ + + YG
Sbjct: 215 SSRDGYSSRDYREPRGFAPSPGEYTHRDYG---------HSSVRDDCPLRGYSDRDGYGG 265
Query: 73 PPTGYTTPTAPQAYSQPVQGYGTGAYDTTTATVTTTQASYAAQSAYGTQPAYPAYGQQPA 132
Y + ++ +P + YG A GT P+Y G+
Sbjct: 266 RDRDYGDHLSRGSHREPFESYG---------------ELRGAAPGRGTPPSYGGGGRY-- 308
Query: 133 ATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSY--GQQSSYGQQSSYGQQPPTSYPPQTGS 190
Y P +Y S ++YG+ Y G+ PPQ S
Sbjct: 309 ----EEYRGYSPDAYSGGRDSYSSSYGRSDRYSRGRHRVGRPDRGLSLSMERGCPPQRDS 364
Query: 191 YSQA 194
YS++
Sbjct: 365 YSRS 368
>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
Length = 1669
Score = 81.3 bits (199), Expect = 2e-15
Identities = 132/468 (28%), Positives = 171/468 (36%), Gaps = 70/468 (14%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G P G G + G+ P PP +P Q + R P
Sbjct: 621 GFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGE 680
Query: 219 MGVYGQESGGFSGPGENRSMSG-PDNRGR----GRGGFDRGGMSRGGRGG-GRGGMGSAG 272
G GQ GF GP + + G P + G GR GF+ + G +G G G+G G
Sbjct: 681 KGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPG 740
Query: 273 ERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVK 332
+G PG P G +G P P E +QG+ L GV
Sbjct: 741 LKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPG 800
Query: 333 MNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKA--AVEWFDGKDFQGSKLKVSLAR 390
+ G P G P G PP K F G D G K A+
Sbjct: 801 I----GPP-------GARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKG-AQ 848
Query: 391 KKPPMNSMRG--GLPPREGR-GMP--------PPLRGGPGGPGGPGGPMGRMG--GRGGD 437
P + G GLP ++G G+P + G PG PG P GP+G G G GD
Sbjct: 849 GLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSP-GPVGAPGLPGEKGD 907
Query: 438 RGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLP 497
GFP G G RG+P G+ GD P G + + K K +
Sbjct: 908 H-GFP--GSSGPRGDPGLKGD----KGDVGLP----GKPGSMDKVDMGSMKGQKGD---- 952
Query: 498 PPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRGMD----R 551
G++G+ GP G +G RG D G PG + G+ G G G +G G+
Sbjct: 953 ------QGEKGQIGPIGEKGSRG---DPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGA 1003
Query: 552 GGFGG--GRRGGPGGPPGPLMEQMGGRRGGRGGPG----KMDKGEHRQ 593
G G G GG G P P + + G G +G PG K KGE Q
Sbjct: 1004 PGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQ 1051
Score = 72.4 bits (176), Expect = 1e-12
Identities = 132/513 (25%), Positives = 171/513 (33%), Gaps = 90/513 (17%)
Query: 130 QPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTG 189
QP + P D G P G + G G G
Sbjct: 889 QPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKG 948
Query: 190 SYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESG----GFSGPGENRSMSG-PDNR 244
+ Q G++ S + P + GV G++ G GP + +SG P
Sbjct: 949 QKGDQGEK--GQIGPIGEKGS--RGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAP 1004
Query: 245 GRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGP---------- 294
G GGM G G +G G G +G PG +G GP
Sbjct: 1005 GLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLRG 1064
Query: 295 ----------PVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHI 344
P P E + +I + G+ S L G + G +
Sbjct: 1065 EKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLP- 1123
Query: 345 YLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPP 404
LD G KG+A + PT A + G D + S K P GLP
Sbjct: 1124 GLDGIPG-VKGEAGLPGTPGPTGPAGQKGEPGSD----GIPGSAGEKGEP------GLPG 1172
Query: 405 REGRGMP--------------PPLRGGPGGPG--------GPGGPMGRMGGRGGDRGGFP 442
R G P P L G PG PG GP GP G+ G G G
Sbjct: 1173 RGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSP--GHA 1230
Query: 443 PRGPRGSRGNPSGGGNVQHRAGDWQCPN-PGC-----GNQNFAWRTECNQCKAPKPEGFL 496
GP+G RG P G + G P PG N W P G +
Sbjct: 1231 TEGPKGDRG-PQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGW---------PGAPG-V 1279
Query: 497 PPPFPPPG--GDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRG-GDRGGFRGGRGMDRGG 553
P P PG G G GG G+ G +G + G PG F+G +G G +G +G D+G
Sbjct: 1280 PGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPG--FQGPKGLPGLQGIKGDQG-DQGV 1336
Query: 554 FGGGRRGGPGGPPGP--LMEQMGGRRGGRGGPG 584
G GP GPPGP +++ G G G PG
Sbjct: 1337 PGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPG 1369
Score = 70.9 bits (172), Expect = 3e-12
Identities = 130/474 (27%), Positives = 164/474 (34%), Gaps = 97/474 (20%)
Query: 154 QQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQ--APSQYSQQSSSYGQQSSF 211
Q G P G G S G+ P Q GS AP ++ SS
Sbjct: 856 QSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSG 915
Query: 212 RQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRG--GGRGGMG 269
+ P G + G PG+ SM D G +G +G G +G +G
Sbjct: 916 PRGDPGLKG----DKGDVGLPGKPGSMDKVDM-----------GSMKGQKGDQGEKGQIG 960
Query: 270 SAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSD------NSAIYVQGLNDSVTLDDLAD 323
GE+G PG P G D G P P D A + G SV L
Sbjct: 961 PIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPG 1020
Query: 324 FFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSK 383
+ GV + G P + DK KG A P + K QG
Sbjct: 1021 TPGEKGVPGIPGPQGSP--GLPGDKGAKGEKGQAGPPGIGIPGLRGE------KGDQGIA 1072
Query: 384 LKVSLARKKPPMNSMRGGLPPREGRGMP--PPLRGGPGGPGGPGGPMGRMGGRGGDRG-- 439
+K S+ G+P GMP P L+G PG G PG P + G GD+G
Sbjct: 1073 GFPGSPGEKGEKGSI--GIP-----GMPGSPGLKGSPGSVGYPGSP--GLPGEKGDKGLP 1123
Query: 440 ---GFP-------------PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTE 483
G P P GP G +G P G + AG + PG + F
Sbjct: 1124 GLDGIPGVKGEAGLPGTPGPTGPAGQKGEP-GSDGIPGSAG--EKGEPGLPGRGF----- 1175
Query: 484 CNQCKAPKPEGFLPPPFPPPGGDRGRGG----PG-----GMRGGRGGLMDRGGPGGMFRG 534
P FP GD+G G PG G+ G +G G PG +
Sbjct: 1176 --------------PGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQP 1221
Query: 535 GRGGDRGGFRGGRGMDRGGFG-GGRRG--GPGGPPG-PLMEQMGGRRGGRGGPG 584
G G G G DRG G G G GP GPPG P ++ + G +G G PG
Sbjct: 1222 GLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPG 1275
Score = 69.7 bits (169), Expect = 7e-12
Identities = 135/489 (27%), Positives = 166/489 (33%), Gaps = 80/489 (16%)
Query: 155 QNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQS--SFR 212
Q G+P G S G G PP + P G Q P S G++ F
Sbjct: 778 QGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGG---QGPPGLSGPPGIKGEKGFPGFP 834
Query: 213 Q-DHPSSMGVYGQESGGFSGPGENRSMSG-PDNRGR-GRGGFDRGGMSRGGRGGGRGGMG 269
D P G G + G G + G P +G G GF G G G G G
Sbjct: 835 GLDMPGPKGDKGAQ--GLPGITGQSGLPGLPGQQGAPGIPGFP-GSKGEMGVMGTPGQPG 891
Query: 270 SAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADF----- 324
S G G PG D G GP DP D + + G S+ D+
Sbjct: 892 SPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKG 951
Query: 325 ----FKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQ 380
Q G + G P G P D P K
Sbjct: 952 DQGEKGQIGPIGEKGSRGDP-------GTPGVPGKDGQAGQPGQPGPKG------DPGIS 998
Query: 381 GSKLKVSLARKKPPMNSMRGGLPPREG-RGMP--PPLRGGPGGPG--------GPGGPMG 429
G+ L K + M GLP G +G+P P +G PG PG G GP G
Sbjct: 999 GTPGAPGLPGPKGSVGGM--GLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPG 1056
Query: 430 ----RMGGRGGDRG--GFP----PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGC----GN 475
+ G GD+G GFP +G +GS G P G+ + PG G
Sbjct: 1057 IGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGE 1116
Query: 476 QNFAWRTECNQCKAPKPEGFLP--PPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFR 533
+ + K E LP P P G +G G G+ G G + G PG F
Sbjct: 1117 KGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFP 1176
Query: 534 G--GRGGDRG-----GFRGGRG-------MDRGGFGG--GRRGGPG--GPPGPLMEQMGG 575
G G GD+G GF G G GF G G +G PG G PG E G
Sbjct: 1177 GFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKG 1236
Query: 576 RRGGRGGPG 584
RG +G PG
Sbjct: 1237 DRGPQGQPG 1245
Score = 67.4 bits (163), Expect = 4e-11
Identities = 132/487 (27%), Positives = 171/487 (35%), Gaps = 79/487 (16%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQ-YSQQSSSYGQQSSFRQDHPS 217
G P G+Q G++ G P TG + + Y G+ + P
Sbjct: 308 GYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGP--KGFPG 365
Query: 218 SMGVYGQESGGFSGPGENRSMSGPDNRG-RGRGGFDRGGM-SRGGRGGGRGGMGSAGERG 275
G G G PG+ + P RG +G GF + GR G G GS G G
Sbjct: 366 LPGQPGPP--GLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPG 423
Query: 276 --GFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLN-DSVTLDDLADFFKQCGVVK 332
G+ GP D GPP P + I +G +S + D+ + G
Sbjct: 424 QPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQG 483
Query: 333 MNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGS---KLKVSLA 389
G P + G P D P + K G L++
Sbjct: 484 PPGEIGFPG-QPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGD 542
Query: 390 RKKP-----PMNSMRGGLPPREGR-GMPPPLRGGPGGPG--GPGGPMGRMG--GRGGDRG 439
+ P P + R G P R+G G+P P +G PG G G GP G +G G GD G
Sbjct: 543 KGDPGFPGQPGMTGRAGSPGRDGHPGLPGP-KGSPGSVGLKGERGPPGGVGFPGSRGDTG 601
Query: 440 -----GFPPRGPRGSRGN---PSGGGNVQHRAGDWQ----CPNPGCGNQNFAWRTECNQC 487
G+ P GP G +G P G G+ + P PG
Sbjct: 602 PPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPG--------------- 646
Query: 488 KAPKPEGFLP--PPFPPPGGDRGRGGPGGMRG--------GRGGLMDRGGPGGMFRGGRG 537
P EG LP P FP P GDRG G G G G+ G+ G PG G
Sbjct: 647 -PPGAEG-LPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLP 704
Query: 538 GDRG-----GFRGGRGMDRGGFGGGRRGGPG-GPPG-------PLMEQMGGRRGGRGGPG 584
GD G G G G+ G++G PG G PG P + G +G G PG
Sbjct: 705 GDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPG 764
Query: 585 KMDKGEH 591
GEH
Sbjct: 765 V--PGEH 769
Score = 67.0 bits (162), Expect = 5e-11
Identities = 75/218 (34%), Positives = 90/218 (41%), Gaps = 33/218 (15%)
Query: 401 GLPPREGRGMPPPLRGGPGGPG--------GPGGPMGRMG--GRGGDRGGFPPRGPRGSR 450
GLP +G PP G PG PG GP GP G G G G+RG P G G
Sbjct: 85 GLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFA 144
Query: 451 GNPSGGG--NVQHRAGDWQCPNPGC---GNQNFAWRTECNQCKAPKPEGF--LPPPFPPP 503
GNP G ++ G+ PG G + F P P G L P PP
Sbjct: 145 GNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFP-----GIPGTPGPPGLPGLQGPVGPP 199
Query: 504 G--GDRGRGGPGGMRGGRG--GLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFG---- 555
G G G GP G G +G GL +G G G G G + ++G F
Sbjct: 200 GFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGE 259
Query: 556 GGRRGGPG--GPPGPLMEQMGGRRGGRGGPGK-MDKGE 590
G++G PG G PG + G+ G RG PGK DKGE
Sbjct: 260 KGQKGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGE 297
Score = 62.4 bits (150), Expect = 1e-09
Identities = 64/194 (32%), Positives = 80/194 (41%), Gaps = 38/194 (19%)
Query: 401 GLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRG--GFPPRGPRGSRGNPSGGGN 458
GLP +G PP G PG PG PG P G++G G +GP+G +G+ G
Sbjct: 188 GLPGLQGPVGPPGFTGPPGPPGPPGPP--------GEKGQMGLSFQGPKGDKGD-QGVSG 238
Query: 459 VQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGG 518
G Q G +FA + E Q P GF P G+ G+ GP G G
Sbjct: 239 PPGVPGQAQVQEKG----DFATKGEKGQKGEP---GFQGMPGVGEKGEPGKPGPRGKPGK 291
Query: 519 RGGLMDRGGPGGMFRGGRGG--DRGGFRGGRGMDRGGFGGGRRGGPGGPP------GPLM 570
G ++G PG G G R G +G +G GP GPP GPL
Sbjct: 292 DGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKG----------EAGPPGPPGIVIGTGPLG 341
Query: 571 EQMGGRRGGRGGPG 584
E+ G RG G PG
Sbjct: 342 EK--GERGYPGTPG 353
Score = 62.0 bits (149), Expect = 2e-09
Identities = 127/468 (27%), Positives = 157/468 (33%), Gaps = 73/468 (15%)
Query: 165 GQQSSYGQQSSYGQQPPTSYPPQTGSY-SQAPSQYSQQSSSYGQQSSFRQDHPSSM-GVY 222
G Q G Q GQ+ T P G+ ++ P S + G QD P G+
Sbjct: 64 GMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIP 123
Query: 223 G-----QESGGFSGPGENRSMSGPDNRG----RGRGGFDRGGMSRGGRGGGRGGMGSAGE 273
G E G PG P G +G G G + G RG G G
Sbjct: 124 GCNGTKGERGPLGPPGLPGFAGNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGT 183
Query: 274 RGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKM 333
G PG GP GPP P GL+ D D GV
Sbjct: 184 PGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGD----QGVSGP 239
Query: 334 NKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKP 393
GQ + + KGD E + + G +G K R KP
Sbjct: 240 PGVPGQAQV---------QEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKPG-PRGKP 289
Query: 394 PMNSMRG-----------GLPPREGRGMPPPLRGGPGGPGGPG-----GPMGRMGGRGGD 437
+ +G G P GR P +G G PG PG GP+G G RG
Sbjct: 290 GKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERG-- 347
Query: 438 RGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPG-CGNQNFAWRTECNQCKAPKPEGFL 496
G P GPRG G P G + + G P PG G F + GF
Sbjct: 348 YPGTP--GPRGEPG-PKGFPGLPGQPGPPGLPVPGQAGAPGFP-----GERGEKGDRGFP 399
Query: 497 PPPFPPPGGDRGRGGPGGMRGGRG------GLMD--RGGPGGMFRGGRGGDRG-----GF 543
P P G G GP G G G G+++ G PG G G G G
Sbjct: 400 GTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGE 459
Query: 544 RGGRG-----MDRGGFGGGRRGGPGGPPGPL-MEQMGGRRGGRGGPGK 585
+G +G D G+ G GP GPPG + G +G RG PG+
Sbjct: 460 KGQKGESCLICDIDGYRG--PPGPQGPPGEIGFPGQPGAKGDRGLPGR 505
Score = 60.1 bits (144), Expect = 6e-09
Identities = 129/486 (26%), Positives = 160/486 (32%), Gaps = 99/486 (20%)
Query: 157 TYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQS-SFRQDH 215
T G P G Q G G P P G Q + G Q S
Sbjct: 183 TPGPPGLPGLQGPVGPPGFTGPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGV 242
Query: 216 PSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERG 275
P V QE G F+ GE +G GF G G+G GE G
Sbjct: 243 PGQAQV--QEKGDFATKGEKGQ--------KGEPGFQ-----------GMPGVGEKGEPG 281
Query: 276 GFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNK 335
G P +G + G P P E I QG A G+V
Sbjct: 282 KPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGE---KGEAGPPGPPGIVIGTG 338
Query: 336 RTGQPMIHIYLDKETGKPKGD-------ATVSYEDPP----TAKAAVEWFDGKDFQGSKL 384
G+ Y T P+G+ PP +A F G+ +G K
Sbjct: 339 PLGEKGERGY--PGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGE--RGEKG 394
Query: 385 KVSLARKKPPMNSMRGGLPPREG-----------------RGMPPPLRGGPGGPGGPG-- 425
P S R GLP G + PP +G PG PG PG
Sbjct: 395 DRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFI 454
Query: 426 GPMGRMGGRG---------GDRGGFPPRGPRGSRGNP-----SGGGNVQHRAGDWQCP-- 469
G +G G +G G RG P+GP G G P G + R G P
Sbjct: 455 GEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGP 514
Query: 470 --------NPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGG 521
PG + + + + K K + P FP G GR G G G G
Sbjct: 515 QGTPGLIGQPGAKGEPGEFYFDL-RLKGDKGD----PGFPGQPGMTGRAGSPGRDGHPGL 569
Query: 522 LMDRGGPGGM-FRGGRGGDRG-GFRGGRGMDRGGFGGGRRGGPG-GPPGPLMEQMGGRRG 578
+G PG + +G RG G GF G RG G G PG GP GP+ ++ G+ G
Sbjct: 570 PGPKGSPGSVGLKGERGPPGGVGFPGSRG------DTGPPGPPGYGPAGPIGDK--GQAG 621
Query: 579 GRGGPG 584
GGPG
Sbjct: 622 FPGGPG 627
Score = 58.9 bits (141), Expect = 1e-08
Identities = 70/206 (33%), Positives = 87/206 (42%), Gaps = 35/206 (16%)
Query: 401 GLPPREGRGMPPPLRG-----GPGGPGGPGGPMGRMG--GRGGDRGGFPPRGPRGSRGNP 453
G+ ++G P L+G G GP GP GP G+ G G G G RGP G+ G P
Sbjct: 43 GVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEPGLPGTKGTRGPPGASGYP 102
Query: 454 SGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPK-PEGFLPPPFPPPGGDRGRGGP 512
G D PG CN K + P G PP P G+ G G
Sbjct: 103 GNPGLPGIPGQDGPPGPPGIPG--------CNGTKGERGPLG--PPGLPGFAGNPGPPGL 152
Query: 513 GGMRGGRGGLMDRGGPGGMFRGGRG-----GDRG--GFRGGRG-MDRGGFGGGRRGGPGG 564
GM+G G ++ PG + +G RG G G G G +G + GF G GP G
Sbjct: 153 PGMKGDPGEILGH-VPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTG--PPGPPG 209
Query: 565 PPGPLME--QMG----GRRGGRGGPG 584
PPGP E QMG G +G +G G
Sbjct: 210 PPGPPGEKGQMGLSFQGPKGDKGDQG 235
Score = 43.1 bits (100), Expect = 7e-04
Identities = 91/356 (25%), Positives = 108/356 (30%), Gaps = 78/356 (21%)
Query: 216 PSSMGVYGQ--ESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRG--------GGR 265
P G GQ E G PG P GRG GF +G +G G
Sbjct: 1141 PGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSP 1200
Query: 266 GGMGSAGERGGFNKPG-----------GPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLND 314
G GS GE+G PG G EGP D GP P + GL
Sbjct: 1201 GIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLP- 1259
Query: 315 SVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWF 374
G+ + G P G P + P +
Sbjct: 1260 --------------GIDGVKGDKGNP----------GWPGAPGVPGPKGDPGFQGMPGIG 1295
Query: 375 DGKDFQGSKLKVSLARKKPPMNSMRG--GLPPREGRGMPPPLRGGPG-----GPGGPGGP 427
GSK + P + +G GLP +G +G PG GP GP GP
Sbjct: 1296 GSPGITGSKGDMG----PPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGP 1351
Query: 428 MGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQC 487
+ G G G P G +G +G P G Q G P P
Sbjct: 1352 YDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQ-QGVTGLVGIPGP---------------- 1394
Query: 488 KAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGF 543
P GF P G+ G GP G RG G G PG M G GF
Sbjct: 1395 --PGIPGF--DGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTPSVDHGF 1446
Score = 40.4 bits (93), Expect = 0.005
Identities = 79/307 (25%), Positives = 96/307 (31%), Gaps = 49/307 (15%)
Query: 148 DQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQ 207
D+ S + G S G S G+Q G P P GS A GQ
Sbjct: 1184 DKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQ 1243
Query: 208 QSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGG 267
G GP + G D G G D+G G G G
Sbjct: 1244 PGL----------------PGLPGPMGPPGLPGID----GVKG-DKGNPGWPGAPGVPGP 1282
Query: 268 MGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQ 327
G G +G G P G D+GPP P +QG+ +
Sbjct: 1283 KGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVP----- 1337
Query: 328 CGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVS 387
G + G P + + E G P E PP K K QG V
Sbjct: 1338 -GAKGLPGPPGPPGPYDIIKGEPGLP------GPEGPPGLKGLQGLPGPKGQQGVTGLVG 1390
Query: 388 LARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPR 447
+ PP G+P +G P + G GP GP GP G G G D G P G
Sbjct: 1391 I--PGPP------GIPGFDG----APGQKGEMGPAGPTGPRGFPGPPGPD--GLP--GSM 1434
Query: 448 GSRGNPS 454
G G PS
Sbjct: 1435 GPPGTPS 1441
>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
sapiens]
Length = 1424
Score = 81.3 bits (199), Expect = 2e-15
Identities = 127/464 (27%), Positives = 174/464 (37%), Gaps = 63/464 (13%)
Query: 148 DQSSY-SQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQA--PSQYSQQSSS 204
D+S + + + G P G+ GQ+ G P + G P
Sbjct: 847 DRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPP 906
Query: 205 YGQQSSFRQDHPSSMGVYGQE-SGGFSGPGENRSMSGPDNRG-----RGRGGFDRGGMSR 258
+ ++ P GV GQ + G G ++ GP +G G +G
Sbjct: 907 GNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGL-KGFAGN 965
Query: 259 GGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTL 318
G G RG G G +G PG GP DLG +P E ++G+ S+
Sbjct: 966 PGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG------LRGIPGSMGN 1019
Query: 319 DDLADFFKQCGVVKMNKRTGQPM---IHIYLDKETGKPK-GDATVSYEDPPTAKAAVEWF 374
+ + G + R G+P IH L + G+P + T PT +
Sbjct: 1020 MGMPGSKGKRGTLGFPGRAGRPGLPGIH-GLQGDKGEPGYSEGTRPGPPGPTGDPGLPGD 1078
Query: 375 DGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG--GPMGRMG 432
GK K + + PP G L P G P G PG PG PG GP G +G
Sbjct: 1079 MGK-------KGEMGQPGPP-----GHLGPAGPEGAP----GSPGSPGLPGKPGPHGDLG 1122
Query: 433 GRGGDRGGFPP--RGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAP 490
+G PP RGP G G P G + R + PG + + E +AP
Sbjct: 1123 FKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGE----KGETGLLRAP 1178
Query: 491 KPEGFLPPPFPPPG-----GDRGRGGPGGMRGGRGGLMDRG--GPGGMFR-GGRGGDRGG 542
P P PG GDRG G G+ G +G + D G GP G+ G G G
Sbjct: 1179 ------PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGA 1232
Query: 543 FRGGRGMDRGGFGGGRRGGPG--GPPGPLMEQMGGRRGGRGGPG 584
G+ +RG G RG PG GPPGP + G +G +G G
Sbjct: 1233 IIPGQTGNRGP--PGSRGSPGAPGPPGPPGSHVIGIKGDKGSMG 1274
Score = 69.7 bits (169), Expect = 7e-12
Identities = 139/521 (26%), Positives = 181/521 (34%), Gaps = 88/521 (16%)
Query: 131 PAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGS 190
P+ SY S + D + G P G + G + G Q G
Sbjct: 275 PSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGD 334
Query: 191 YS----QAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRG- 245
+ P++Y G + + P G G + G SGP G G
Sbjct: 335 IGPPGFRGPTEYYDTYQEKGDEGT--PGPPGPRGARGPQ--GPSGPPGVPGSPGSSRPGL 390
Query: 246 RGRGGFDRGGMSRGGRGG-GRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN 304
RG G+ S+G RG G+ MG+ G G PG P GP GPP D
Sbjct: 391 RGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPP---GPPGD------- 440
Query: 305 SAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHI----YLDKETGKPKGDATVS 360
++ +G L + G+ ++ G+P + Y+ G P
Sbjct: 441 -IVFRKGPPGD---HGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHG 496
Query: 361 YEDPPTAKAAVEWFDGKDFQGSKLKVSL--------ARKKPPMNSMRGGLPPREGR-GMP 411
+ P + A K GS L A+ P + +G EG+ G+P
Sbjct: 497 VKGIPGRQGAAGL---KGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVP 553
Query: 412 --PPLRGGPGG------PGGPG-----GPMGRMG--GRGGDRG--------GFP-PRGPR 447
P LRG PG PG PG GP G + G GD+G G P P GP
Sbjct: 554 GDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPA 613
Query: 448 GSRG-NPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGD 506
G G P G +Q G P P R E + P P PP P P G
Sbjct: 614 GPPGYGPQGEPGLQGTQGVPGAPGPP---GEAGPRGELS-VSTPVPG---PPGPPGPPGH 666
Query: 507 RGRGGPGGMRGGRGGLMDRGGPG--------GMFRGGRGGDRG--GFRGGRGMDRGGFGG 556
G GP G+ G G D G PG G+ G G +G GF G +G
Sbjct: 667 PGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKM 726
Query: 557 GRRGGPGGP--PGPLMEQMGGRRGGRGGPG----KMDKGEH 591
G G PG P PG E GG G PG + + GEH
Sbjct: 727 GEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEH 767
Score = 65.9 bits (159), Expect = 1e-10
Identities = 112/408 (27%), Positives = 142/408 (34%), Gaps = 63/408 (15%)
Query: 212 RQDHPSSMGVYG-QESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGS 270
R P G++G Q G G E P G D G G+ G G +G
Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGP 1096
Query: 271 AGERGGFNKPGGPM---DEGPDLDL---------------GPPVDPDEDSDNSAIYVQGL 312
AG G PG P GP DL GPP P + ++G
Sbjct: 1097 AGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGD 1156
Query: 313 NDSVTLDDLADFFKQCGVVKMNKRT-GQPMIHIYLDKETGKP-----KGDATVSYEDPPT 366
+ A + G+++ G P + G P G + P
Sbjct: 1157 QGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQ-GAKGDRGAPGFPGLPGRKGAMGDAGPR 1215
Query: 367 AKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGL-PPREGRGMPPPLRGGPGGPGGPG 425
+E F G PP + G + P + G PP RG PG PG PG
Sbjct: 1216 GPTGIEGFPG----------------PP--GLPGAIIPGQTGNRGPPGSRGSPGAPGPPG 1257
Query: 426 GPMGRMGGRGGDRG--GFP-PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRT 482
P + G GD+G G P P+GP G+ G+ G + G P P G+ F
Sbjct: 1258 PPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRL-GAPGTPGLPGPR-GDPGFQGFP 1315
Query: 483 ECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG- 541
K GFL PP G G GP G+RG G L PG G G+ G
Sbjct: 1316 GVKGEKG--NPGFLGSIGPP--GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGM 1371
Query: 542 -GFRGGRGMDRGGFGGGRRGGPG-----GPPGPLMEQMGGRRGGRGGP 583
G G G G RG PG G PGP E+ G +G +G P
Sbjct: 1372 QGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEK--GNKGSKGEP 1417
Score = 62.4 bits (150), Expect = 1e-09
Identities = 131/512 (25%), Positives = 159/512 (31%), Gaps = 79/512 (15%)
Query: 122 PAYPAYGQQPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPP 181
P P P P P Q Q T G P + G G + P
Sbjct: 598 PGDPGSPGSPGPAGPAGPPGYGP----QGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTP 653
Query: 182 TSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGP 241
PP P P G G GF GP GP
Sbjct: 654 VPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGP------PGP 707
Query: 242 DNRGRGRGGFD--RGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPD 299
+G GF +G + G+ G G G G G +P M GP G P P
Sbjct: 708 ----KGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP----GTPGFPG 759
Query: 300 EDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKP--KGDA 357
E ++ G + + L L G ++ G P + G P +G
Sbjct: 760 ERGNS------GEHGEIGLPGLPGLPGTPGNEGLDGPRGDP-------GQPGPPGEQGPP 806
Query: 358 TVSYEDPPTAKAAVEWFDGKDFQGSKLKVS---------LARKKPPMNSMRGGLPPREGR 408
E P A+ K QG + K L R P + G+P +G
Sbjct: 807 GRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGE 866
Query: 409 GMPPPLRGGPGGPG--GPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDW 466
P RG PG PG GP G G +G G G P GP G+ G P G+
Sbjct: 867 MGPLGQRGYPGNPGILGPPGEDGVIGMMGFP-GAIGPPGPPGNPGTPGQRGSPGIPGVKG 925
Query: 467 QCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRG 526
Q PG + Q P P GD+G G G G G +RG
Sbjct: 926 QRGTPGAKGE---------QGDKGNPG---PSEISHVIGDKGEPGLKGFAGNPGEKGNRG 973
Query: 527 GPGGMFRGGRGGDRG--GFRGGRGMDRGGFGG----GRRGGPGGPPGPLMEQMGGRRGGR 580
PG G G G G G RG D G G G RG PG M G+RG
Sbjct: 974 VPGMPGLKGLKGLPGPAGPPGPRG-DLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTL 1032
Query: 581 GGPGKM-------------DKGEHRQERRDRP 599
G PG+ DKGE RP
Sbjct: 1033 GFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRP 1064
Score = 62.0 bits (149), Expect = 2e-09
Identities = 107/374 (28%), Positives = 137/374 (36%), Gaps = 92/374 (24%)
Query: 237 SMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPV 296
+++GPDNR G G +G MG G G PG E + G P
Sbjct: 247 TLTGPDNR-----------TDLKGEKGDKGAMGEPGPPGPSGLPG----ESYGSEKGAPG 291
Query: 297 DPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGD 356
DP GL D + F GV K N+ G P + + D G+ KGD
Sbjct: 292 DP------------GLQGKPGKDGVPGFPGSEGV-KGNR--GFPGL-MGEDGIKGQ-KGD 334
Query: 357 ATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRG 416
PP + E++D +G + PP PR RG P G
Sbjct: 335 I-----GPPGFRGPTEYYDTYQEKGDE-----GTPGPP--------GPRGARGPQGP-SG 375
Query: 417 GPGGPGGPGGPMGRMGGRGGDRGGFPP-RGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGN 475
PG PG PG R G RG G+P +G +G RG P G + G +PGC
Sbjct: 376 PPGVPGSPGS--SRPGLRGAP--GWPGLKGSKGERGRP--GKDAMGTPG-----SPGCAG 424
Query: 476 QNFAWRTECNQCKAPKPEGFLPPPFPP--------PGGDRGRGGPGGMRGGRGGLMDRGG 527
+P G PP PP P GD G G G G G +G
Sbjct: 425 -------------SPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGE 471
Query: 528 PGGM-----FRGGRGGDRG--GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGR 580
PG + + G G G G G +G+ G +G PG P + G G +
Sbjct: 472 PGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQ 531
Query: 581 GGPG-KMDKGEHRQ 593
G PG K +KGE Q
Sbjct: 532 GDPGLKGEKGETLQ 545
Score = 60.8 bits (146), Expect = 3e-09
Identities = 101/379 (26%), Positives = 132/379 (34%), Gaps = 98/379 (25%)
Query: 228 GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRG-------GGRGGMGSAGERGGFNKP 280
G GP ++SG + +G G S G G G +G G G +G P
Sbjct: 578 GLPGPKGELALSG-EKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAP 636
Query: 281 GGPMDEGPDLDL-------GPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKM 333
G P + GP +L GPP P G+ S+ +CG +
Sbjct: 637 GPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSL---------GKCGDPGL 687
Query: 334 NKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK- 392
G+P G + + PP K + F G+K + K
Sbjct: 688 PGPDGEP--------------GIPGIGFPGPPGPKG------DQGFPGTKGSLGCPGKMG 727
Query: 393 PPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGN 452
P + GLP +G P PGGPG PG P G+RG G G G
Sbjct: 728 EPGLPGKPGLPGAKGE----PAVAMPGGPGTPGFP--------GERGNSGEHGEIGLPGL 775
Query: 453 PSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPP---FPPPGGDRGR 509
P G + D +PG P P G PP P G +G
Sbjct: 776 PGLPGTPGNEGLDGPRGDPG----------------QPGPPGEQGPPGRCIEGPRGAQGL 819
Query: 510 GGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGG--GRRGGPG--GP 565
G G++G +G R G+ G +G G G+DR GF G G G PG G
Sbjct: 820 PGLNGLKGQQG------------RRGKTGPKGD-PGIPGLDRSGFPGETGSPGIPGHQGE 866
Query: 566 PGPLMEQMGGRRGGRGGPG 584
GPL G+RG G PG
Sbjct: 867 MGPL-----GQRGYPGNPG 880
Score = 55.8 bits (133), Expect = 1e-07
Identities = 74/234 (31%), Positives = 91/234 (38%), Gaps = 63/234 (26%)
Query: 401 GLPPREG----RGMP--PPLRGGPGGPGGPG--GPMGRMG--GRGGDRG--GFP------ 442
GLP G RG+ P G PG PG PG GP G +G G G +G GFP
Sbjct: 82 GLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTL 141
Query: 443 -------PRGPRGSRGNPSGGGNVQHRA-GDWQCPNPGCGNQNFAWRTECNQCKAPKPEG 494
G +G +G P+ +++ A GD P G Q P P G
Sbjct: 142 GYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAP-GPQGL-----------PGPPG 189
Query: 495 FLPPPFPPPGGDRGRGGPGGM--RGGRGGLMDR-----------------GGPGGMFRGG 535
F P P PPG G PG M RG +G + +R G PG +
Sbjct: 190 F-PGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTL 248
Query: 536 RGGD-RGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDK 588
G D R +G +G D+G G GP G PG E G +G G PG K
Sbjct: 249 TGPDNRTDLKGEKG-DKGAMGEPGPPGPSGLPG---ESYGSEKGAPGDPGLQGK 298
Score = 46.2 bits (108), Expect = 9e-05
Identities = 61/190 (32%), Positives = 76/190 (40%), Gaps = 27/190 (14%)
Query: 415 RGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNP--SGGGNVQHRAG-DWQCPNP 471
+G PG PG PG G G G P+GP+G G P +G V+ +G +P
Sbjct: 51 KGFPGPPGSPG-----QKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSP 105
Query: 472 GC----GNQNFAWRTECNQCKAPKPE-GFLPPPFPPPGGDRGRGGPGGMRGGRGG----- 521
G GN C K E GF P P G G G G++G +G
Sbjct: 106 GLPGTPGNTGPYGLVGVPGCSGSKGEQGF--PGLPGTLGYPGIPGAAGLKGQKGAPAKEE 163
Query: 522 ---LMDRGGPGGMFRGGRGGDRG--GFRG--GRGMDRGGFGGGRRGGPGGPPGPLMEQMG 574
L +G PG G G G GF G G G FG GP GP G + E++
Sbjct: 164 DIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVI 223
Query: 575 GRRGGRGGPG 584
G +G RG G
Sbjct: 224 GHKGERGVKG 233
Score = 39.3 bits (90), Expect = 0.010
Identities = 81/318 (25%), Positives = 100/318 (31%), Gaps = 66/318 (20%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G P S G G Q G P +TG P + + P
Sbjct: 1143 GFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGL 1202
Query: 219 MGVYGQ--ESG--------GFSGP---------GENRSMSGPDNRGRGRGGFDRG--GMS 257
G G ++G GF GP G+ + P +RG G G
Sbjct: 1203 PGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSH 1262
Query: 258 RGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVT 317
G G +G MG G +G PG D GP LG P P QG
Sbjct: 1263 VIGIKGDKGSMGHPGPKG---PPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPG--- 1316
Query: 318 LDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGK 377
VK K + I G PKG V DP T K
Sbjct: 1317 -------------VKGEKGNPGFLGSIGPPGPIG-PKGPPGVR-GDPGTLKI-------- 1353
Query: 378 DFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG--GRG 435
+SL P + G P +G PP GP G GP GP G+ G G+
Sbjct: 1354 --------ISLPGSPGPPGT--PGEPGMQGEPGPP----GPPGNLGPCGPRGKPGKDGKP 1399
Query: 436 GDRGGFPPRGPRGSRGNP 453
G G +G +GS+G P
Sbjct: 1400 GTPGPAGEKGNKGSKGEP 1417
Score = 32.3 bits (72), Expect = 1.3
Identities = 38/125 (30%), Positives = 48/125 (38%), Gaps = 27/125 (21%)
Query: 484 CNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-- 541
C+ K K E FP P G G+ G G G G +G PG G G RG
Sbjct: 41 CDGAKGEKGE----KGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGIS 96
Query: 542 ---GFRGGRGM-----DRGGFG-------GGRRGGPGGP--PG----PLMEQMGGRRGGR 580
GF G G+ + G +G G +G G P PG P + G +G +
Sbjct: 97 GLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQK 156
Query: 581 GGPGK 585
G P K
Sbjct: 157 GAPAK 161
>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
sapiens]
Length = 1494
Score = 81.3 bits (199), Expect = 2e-15
Identities = 127/464 (27%), Positives = 174/464 (37%), Gaps = 63/464 (13%)
Query: 148 DQSSY-SQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQA--PSQYSQQSSS 204
D+S + + + G P G+ GQ+ G P + G P
Sbjct: 847 DRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPP 906
Query: 205 YGQQSSFRQDHPSSMGVYGQE-SGGFSGPGENRSMSGPDNRG-----RGRGGFDRGGMSR 258
+ ++ P GV GQ + G G ++ GP +G G +G
Sbjct: 907 GNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGL-KGFAGN 965
Query: 259 GGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTL 318
G G RG G G +G PG GP DLG +P E ++G+ S+
Sbjct: 966 PGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG------LRGIPGSMGN 1019
Query: 319 DDLADFFKQCGVVKMNKRTGQPM---IHIYLDKETGKPK-GDATVSYEDPPTAKAAVEWF 374
+ + G + R G+P IH L + G+P + T PT +
Sbjct: 1020 MGMPGSKGKRGTLGFPGRAGRPGLPGIH-GLQGDKGEPGYSEGTRPGPPGPTGDPGLPGD 1078
Query: 375 DGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG--GPMGRMG 432
GK K + + PP G L P G P G PG PG PG GP G +G
Sbjct: 1079 MGK-------KGEMGQPGPP-----GHLGPAGPEGAP----GSPGSPGLPGKPGPHGDLG 1122
Query: 433 GRGGDRGGFPP--RGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAP 490
+G PP RGP G G P G + R + PG + + E +AP
Sbjct: 1123 FKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGE----KGETGLLRAP 1178
Query: 491 KPEGFLPPPFPPPG-----GDRGRGGPGGMRGGRGGLMDRG--GPGGMFR-GGRGGDRGG 542
P P PG GDRG G G+ G +G + D G GP G+ G G G
Sbjct: 1179 ------PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGA 1232
Query: 543 FRGGRGMDRGGFGGGRRGGPG--GPPGPLMEQMGGRRGGRGGPG 584
G+ +RG G RG PG GPPGP + G +G +G G
Sbjct: 1233 IIPGQTGNRGP--PGSRGSPGAPGPPGPPGSHVIGIKGDKGSMG 1274
Score = 69.7 bits (169), Expect = 7e-12
Identities = 139/521 (26%), Positives = 181/521 (34%), Gaps = 88/521 (16%)
Query: 131 PAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGS 190
P+ SY S + D + G P G + G + G Q G
Sbjct: 275 PSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGD 334
Query: 191 YS----QAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRG- 245
+ P++Y G + + P G G + G SGP G G
Sbjct: 335 IGPPGFRGPTEYYDTYQEKGDEGT--PGPPGPRGARGPQ--GPSGPPGVPGSPGSSRPGL 390
Query: 246 RGRGGFDRGGMSRGGRGG-GRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN 304
RG G+ S+G RG G+ MG+ G G PG P GP GPP D
Sbjct: 391 RGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPP---GPPGD------- 440
Query: 305 SAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHI----YLDKETGKPKGDATVS 360
++ +G L + G+ ++ G+P + Y+ G P
Sbjct: 441 -IVFRKGPPGD---HGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHG 496
Query: 361 YEDPPTAKAAVEWFDGKDFQGSKLKVSL--------ARKKPPMNSMRGGLPPREGR-GMP 411
+ P + A K GS L A+ P + +G EG+ G+P
Sbjct: 497 VKGIPGRQGAAGL---KGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVP 553
Query: 412 --PPLRGGPGG------PGGPG-----GPMGRMG--GRGGDRG--------GFP-PRGPR 447
P LRG PG PG PG GP G + G GD+G G P P GP
Sbjct: 554 GDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPA 613
Query: 448 GSRG-NPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGD 506
G G P G +Q G P P R E + P P PP P P G
Sbjct: 614 GPPGYGPQGEPGLQGTQGVPGAPGPP---GEAGPRGELS-VSTPVPG---PPGPPGPPGH 666
Query: 507 RGRGGPGGMRGGRGGLMDRGGPG--------GMFRGGRGGDRG--GFRGGRGMDRGGFGG 556
G GP G+ G G D G PG G+ G G +G GF G +G
Sbjct: 667 PGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKM 726
Query: 557 GRRGGPGGP--PGPLMEQMGGRRGGRGGPG----KMDKGEH 591
G G PG P PG E GG G PG + + GEH
Sbjct: 727 GEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEH 767
Score = 68.2 bits (165), Expect = 2e-11
Identities = 113/409 (27%), Positives = 143/409 (34%), Gaps = 63/409 (15%)
Query: 212 RQDHPSSMGVYG-QESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGS 270
R P G++G Q G G E P G D G G+ G G +G
Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGP 1096
Query: 271 AGERGGFNKPGGPM---DEGPDLDL---------------GPPVDPDEDSDNSAIYVQGL 312
AG G PG P GP DL GPP P + ++G
Sbjct: 1097 AGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGD 1156
Query: 313 NDSVTLDDLADFFKQCGVVKMNKRT-GQPMIHIYLDKETGKP-----KGDATVSYEDPPT 366
+ A + G+++ G P + G P G + P
Sbjct: 1157 QGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQ-GAKGDRGAPGFPGLPGRKGAMGDAGPR 1215
Query: 367 AKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGL-PPREGRGMPPPLRGGPGGPGGPG 425
+E F G PP + G + P + G PP RG PG PG PG
Sbjct: 1216 GPTGIEGFPG----------------PP--GLPGAIIPGQTGNRGPPGSRGSPGAPGPPG 1257
Query: 426 GPMGRMGGRGGDRG--GFP-PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRT 482
P + G GD+G G P P+GP G+ G+ G + G P P G+ F
Sbjct: 1258 PPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRL-GAPGTPGLPGPR-GDPGFQGFP 1315
Query: 483 ECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG- 541
K GFL PP G G GP G+RG G L PG G G+ G
Sbjct: 1316 GVKGEKG--NPGFLGSIGPP--GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGM 1371
Query: 542 -GFRGGRGMDRGGFGGGRRGGPG-----GPPGPLMEQMGGRRGGRGGPG 584
G G G G RG PG G PGP E+ G +G +G PG
Sbjct: 1372 QGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEK--GNKGSKGEPG 1418
Score = 62.4 bits (150), Expect = 1e-09
Identities = 131/512 (25%), Positives = 159/512 (31%), Gaps = 79/512 (15%)
Query: 122 PAYPAYGQQPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPP 181
P P P P P Q Q T G P + G G + P
Sbjct: 598 PGDPGSPGSPGPAGPAGPPGYGP----QGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTP 653
Query: 182 TSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGP 241
PP P P G G GF GP GP
Sbjct: 654 VPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGP------PGP 707
Query: 242 DNRGRGRGGFD--RGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPD 299
+G GF +G + G+ G G G G G +P M GP G P P
Sbjct: 708 ----KGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP----GTPGFPG 759
Query: 300 EDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKP--KGDA 357
E ++ G + + L L G ++ G P + G P +G
Sbjct: 760 ERGNS------GEHGEIGLPGLPGLPGTPGNEGLDGPRGDP-------GQPGPPGEQGPP 806
Query: 358 TVSYEDPPTAKAAVEWFDGKDFQGSKLKVS---------LARKKPPMNSMRGGLPPREGR 408
E P A+ K QG + K L R P + G+P +G
Sbjct: 807 GRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGE 866
Query: 409 GMPPPLRGGPGGPG--GPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDW 466
P RG PG PG GP G G +G G G P GP G+ G P G+
Sbjct: 867 MGPLGQRGYPGNPGILGPPGEDGVIGMMGFP-GAIGPPGPPGNPGTPGQRGSPGIPGVKG 925
Query: 467 QCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRG 526
Q PG + Q P P GD+G G G G G +RG
Sbjct: 926 QRGTPGAKGE---------QGDKGNPG---PSEISHVIGDKGEPGLKGFAGNPGEKGNRG 973
Query: 527 GPGGMFRGGRGGDRG--GFRGGRGMDRGGFGG----GRRGGPGGPPGPLMEQMGGRRGGR 580
PG G G G G G RG D G G G RG PG M G+RG
Sbjct: 974 VPGMPGLKGLKGLPGPAGPPGPRG-DLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTL 1032
Query: 581 GGPGKM-------------DKGEHRQERRDRP 599
G PG+ DKGE RP
Sbjct: 1033 GFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRP 1064
Score = 62.0 bits (149), Expect = 2e-09
Identities = 107/374 (28%), Positives = 137/374 (36%), Gaps = 92/374 (24%)
Query: 237 SMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPV 296
+++GPDNR G G +G MG G G PG E + G P
Sbjct: 247 TLTGPDNR-----------TDLKGEKGDKGAMGEPGPPGPSGLPG----ESYGSEKGAPG 291
Query: 297 DPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGD 356
DP GL D + F GV K N+ G P + + D G+ KGD
Sbjct: 292 DP------------GLQGKPGKDGVPGFPGSEGV-KGNR--GFPGL-MGEDGIKGQ-KGD 334
Query: 357 ATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRG 416
PP + E++D +G + PP PR RG P G
Sbjct: 335 I-----GPPGFRGPTEYYDTYQEKGDE-----GTPGPP--------GPRGARGPQGP-SG 375
Query: 417 GPGGPGGPGGPMGRMGGRGGDRGGFPP-RGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGN 475
PG PG PG R G RG G+P +G +G RG P G + G +PGC
Sbjct: 376 PPGVPGSPGS--SRPGLRGAP--GWPGLKGSKGERGRP--GKDAMGTPG-----SPGCAG 424
Query: 476 QNFAWRTECNQCKAPKPEGFLPPPFPP--------PGGDRGRGGPGGMRGGRGGLMDRGG 527
+P G PP PP P GD G G G G G +G
Sbjct: 425 -------------SPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGE 471
Query: 528 PGGM-----FRGGRGGDRG--GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGR 580
PG + + G G G G G +G+ G +G PG P + G G +
Sbjct: 472 PGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQ 531
Query: 581 GGPG-KMDKGEHRQ 593
G PG K +KGE Q
Sbjct: 532 GDPGLKGEKGETLQ 545
Score = 60.8 bits (146), Expect = 3e-09
Identities = 101/379 (26%), Positives = 132/379 (34%), Gaps = 98/379 (25%)
Query: 228 GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRG-------GGRGGMGSAGERGGFNKP 280
G GP ++SG + +G G S G G G +G G G +G P
Sbjct: 578 GLPGPKGELALSG-EKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAP 636
Query: 281 GGPMDEGPDLDL-------GPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKM 333
G P + GP +L GPP P G+ S+ +CG +
Sbjct: 637 GPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSL---------GKCGDPGL 687
Query: 334 NKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK- 392
G+P G + + PP K + F G+K + K
Sbjct: 688 PGPDGEP--------------GIPGIGFPGPPGPKG------DQGFPGTKGSLGCPGKMG 727
Query: 393 PPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGN 452
P + GLP +G P PGGPG PG P G+RG G G G
Sbjct: 728 EPGLPGKPGLPGAKGE----PAVAMPGGPGTPGFP--------GERGNSGEHGEIGLPGL 775
Query: 453 PSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPP---FPPPGGDRGR 509
P G + D +PG P P G PP P G +G
Sbjct: 776 PGLPGTPGNEGLDGPRGDPG----------------QPGPPGEQGPPGRCIEGPRGAQGL 819
Query: 510 GGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGG--GRRGGPG--GP 565
G G++G +G R G+ G +G G G+DR GF G G G PG G
Sbjct: 820 PGLNGLKGQQG------------RRGKTGPKGD-PGIPGLDRSGFPGETGSPGIPGHQGE 866
Query: 566 PGPLMEQMGGRRGGRGGPG 584
GPL G+RG G PG
Sbjct: 867 MGPL-----GQRGYPGNPG 880
Score = 55.8 bits (133), Expect = 1e-07
Identities = 74/234 (31%), Positives = 91/234 (38%), Gaps = 63/234 (26%)
Query: 401 GLPPREG----RGMP--PPLRGGPGGPGGPG--GPMGRMG--GRGGDRG--GFP------ 442
GLP G RG+ P G PG PG PG GP G +G G G +G GFP
Sbjct: 82 GLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTL 141
Query: 443 -------PRGPRGSRGNPSGGGNVQHRA-GDWQCPNPGCGNQNFAWRTECNQCKAPKPEG 494
G +G +G P+ +++ A GD P G Q P P G
Sbjct: 142 GYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAP-GPQGL-----------PGPPG 189
Query: 495 FLPPPFPPPGGDRGRGGPGGM--RGGRGGLMDR-----------------GGPGGMFRGG 535
F P P PPG G PG M RG +G + +R G PG +
Sbjct: 190 F-PGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTL 248
Query: 536 RGGD-RGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDK 588
G D R +G +G D+G G GP G PG E G +G G PG K
Sbjct: 249 TGPDNRTDLKGEKG-DKGAMGEPGPPGPSGLPG---ESYGSEKGAPGDPGLQGK 298
Score = 52.8 bits (125), Expect = 9e-07
Identities = 55/172 (31%), Positives = 65/172 (37%), Gaps = 31/172 (18%)
Query: 391 KKPPMNSMRGGLPPREGR----GMPPPLRGGPGGPGGPG--GPMGRMGGRG--GDRGGFP 442
K PP + G P R G G+P P RG PG G PG G G G G G G
Sbjct: 1279 KGPPGTAGDMGPPGRLGAPGTPGLPGP-RGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIG 1337
Query: 443 PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPP 502
P+GP G RG+P + PG P +G PP PP
Sbjct: 1338 PKGPPGVRGDPGTLKIISLPGSPGPPGTPG----------------EPGMQGEPGPPGPP 1381
Query: 503 ----PGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRG 548
P G RG+ G G G G ++G G G G G G +G RG
Sbjct: 1382 GNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRG 1433
Score = 46.2 bits (108), Expect = 9e-05
Identities = 61/190 (32%), Positives = 76/190 (40%), Gaps = 27/190 (14%)
Query: 415 RGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNP--SGGGNVQHRAG-DWQCPNP 471
+G PG PG PG G G G P+GP+G G P +G V+ +G +P
Sbjct: 51 KGFPGPPGSPG-----QKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSP 105
Query: 472 GC----GNQNFAWRTECNQCKAPKPE-GFLPPPFPPPGGDRGRGGPGGMRGGRGG----- 521
G GN C K E GF P P G G G G++G +G
Sbjct: 106 GLPGTPGNTGPYGLVGVPGCSGSKGEQGF--PGLPGTLGYPGIPGAAGLKGQKGAPAKEE 163
Query: 522 ---LMDRGGPGGMFRGGRGGDRG--GFRG--GRGMDRGGFGGGRRGGPGGPPGPLMEQMG 574
L +G PG G G G GF G G G FG GP GP G + E++
Sbjct: 164 DIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVI 223
Query: 575 GRRGGRGGPG 584
G +G RG G
Sbjct: 224 GHKGERGVKG 233
Score = 41.2 bits (95), Expect = 0.003
Identities = 82/323 (25%), Positives = 102/323 (31%), Gaps = 66/323 (20%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G P S G G Q G P +TG P + + P
Sbjct: 1143 GFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGL 1202
Query: 219 MGVYGQ--ESG--------GFSGP---------GENRSMSGPDNRGRGRGGFDRG--GMS 257
G G ++G GF GP G+ + P +RG G G
Sbjct: 1203 PGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSH 1262
Query: 258 RGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVT 317
G G +G MG G +G PG D GP LG P P QG
Sbjct: 1263 VIGIKGDKGSMGHPGPKG---PPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPG--- 1316
Query: 318 LDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGK 377
VK K + I G PKG V DP T K
Sbjct: 1317 -------------VKGEKGNPGFLGSIGPPGPIG-PKGPPGVR-GDPGTLKI-------- 1353
Query: 378 DFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG--GRG 435
+SL P + G P +G PP GP G GP GP G+ G G+
Sbjct: 1354 --------ISLPGSPGPPGT--PGEPGMQGEPGPP----GPPGNLGPCGPRGKPGKDGKP 1399
Query: 436 GDRGGFPPRGPRGSRGNPSGGGN 458
G G +G +GS+G P G+
Sbjct: 1400 GTPGPAGEKGNKGSKGEPGPAGS 1422
Score = 32.3 bits (72), Expect = 1.3
Identities = 38/125 (30%), Positives = 48/125 (38%), Gaps = 27/125 (21%)
Query: 484 CNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-- 541
C+ K K E FP P G G+ G G G G +G PG G G RG
Sbjct: 41 CDGAKGEKGE----KGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGIS 96
Query: 542 ---GFRGGRGM-----DRGGFG-------GGRRGGPGGP--PG----PLMEQMGGRRGGR 580
GF G G+ + G +G G +G G P PG P + G +G +
Sbjct: 97 GLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQK 156
Query: 581 GGPGK 585
G P K
Sbjct: 157 GAPAK 161
>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
sapiens]
Length = 1637
Score = 81.3 bits (199), Expect = 2e-15
Identities = 127/464 (27%), Positives = 174/464 (37%), Gaps = 63/464 (13%)
Query: 148 DQSSY-SQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQA--PSQYSQQSSS 204
D+S + + + G P G+ GQ+ G P + G P
Sbjct: 847 DRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPP 906
Query: 205 YGQQSSFRQDHPSSMGVYGQE-SGGFSGPGENRSMSGPDNRG-----RGRGGFDRGGMSR 258
+ ++ P GV GQ + G G ++ GP +G G +G
Sbjct: 907 GNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIGDKGEPGL-KGFAGN 965
Query: 259 GGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVTL 318
G G RG G G +G PG GP DLG +P E ++G+ S+
Sbjct: 966 PGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG------LRGIPGSMGN 1019
Query: 319 DDLADFFKQCGVVKMNKRTGQPM---IHIYLDKETGKPK-GDATVSYEDPPTAKAAVEWF 374
+ + G + R G+P IH L + G+P + T PT +
Sbjct: 1020 MGMPGSKGKRGTLGFPGRAGRPGLPGIH-GLQGDKGEPGYSEGTRPGPPGPTGDPGLPGD 1078
Query: 375 DGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPG--GPMGRMG 432
GK K + + PP G L P G P G PG PG PG GP G +G
Sbjct: 1079 MGK-------KGEMGQPGPP-----GHLGPAGPEGAP----GSPGSPGLPGKPGPHGDLG 1122
Query: 433 GRGGDRGGFPP--RGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAP 490
+G PP RGP G G P G + R + PG + + E +AP
Sbjct: 1123 FKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGE----KGETGLLRAP 1178
Query: 491 KPEGFLPPPFPPPG-----GDRGRGGPGGMRGGRGGLMDRG--GPGGMFR-GGRGGDRGG 542
P P PG GDRG G G+ G +G + D G GP G+ G G G
Sbjct: 1179 ------PGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGA 1232
Query: 543 FRGGRGMDRGGFGGGRRGGPG--GPPGPLMEQMGGRRGGRGGPG 584
G+ +RG G RG PG GPPGP + G +G +G G
Sbjct: 1233 IIPGQTGNRGP--PGSRGSPGAPGPPGPPGSHVIGIKGDKGSMG 1274
Score = 69.7 bits (169), Expect = 7e-12
Identities = 139/521 (26%), Positives = 181/521 (34%), Gaps = 88/521 (16%)
Query: 131 PAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGS 190
P+ SY S + D + G P G + G + G Q G
Sbjct: 275 PSGLPGESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGD 334
Query: 191 YS----QAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRG- 245
+ P++Y G + + P G G + G SGP G G
Sbjct: 335 IGPPGFRGPTEYYDTYQEKGDEGT--PGPPGPRGARGPQ--GPSGPPGVPGSPGSSRPGL 390
Query: 246 RGRGGFDRGGMSRGGRGG-GRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDN 304
RG G+ S+G RG G+ MG+ G G PG P GP GPP D
Sbjct: 391 RGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGSPGLPGSPGPP---GPPGD------- 440
Query: 305 SAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHI----YLDKETGKPKGDATVS 360
++ +G L + G+ ++ G+P + Y+ G P
Sbjct: 441 -IVFRKGPPGD---HGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHG 496
Query: 361 YEDPPTAKAAVEWFDGKDFQGSKLKVSL--------ARKKPPMNSMRGGLPPREGR-GMP 411
+ P + A K GS L A+ P + +G EG+ G+P
Sbjct: 497 VKGIPGRQGAAGL---KGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVP 553
Query: 412 --PPLRGGPGG------PGGPG-----GPMGRMG--GRGGDRG--------GFP-PRGPR 447
P LRG PG PG PG GP G + G GD+G G P P GP
Sbjct: 554 GDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPA 613
Query: 448 GSRG-NPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGD 506
G G P G +Q G P P R E + P P PP P P G
Sbjct: 614 GPPGYGPQGEPGLQGTQGVPGAPGPP---GEAGPRGELS-VSTPVPG---PPGPPGPPGH 666
Query: 507 RGRGGPGGMRGGRGGLMDRGGPG--------GMFRGGRGGDRG--GFRGGRGMDRGGFGG 556
G GP G+ G G D G PG G+ G G +G GF G +G
Sbjct: 667 PGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKM 726
Query: 557 GRRGGPGGP--PGPLMEQMGGRRGGRGGPG----KMDKGEH 591
G G PG P PG E GG G PG + + GEH
Sbjct: 727 GEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEH 767
Score = 68.2 bits (165), Expect = 2e-11
Identities = 113/409 (27%), Positives = 143/409 (34%), Gaps = 63/409 (15%)
Query: 212 RQDHPSSMGVYG-QESGGFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGS 270
R P G++G Q G G E P G D G G+ G G +G
Sbjct: 1037 RAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGP 1096
Query: 271 AGERGGFNKPGGPM---DEGPDLDL---------------GPPVDPDEDSDNSAIYVQGL 312
AG G PG P GP DL GPP P + ++G
Sbjct: 1097 AGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGD 1156
Query: 313 NDSVTLDDLADFFKQCGVVKMNKRT-GQPMIHIYLDKETGKP-----KGDATVSYEDPPT 366
+ A + G+++ G P + G P G + P
Sbjct: 1157 QGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQ-GAKGDRGAPGFPGLPGRKGAMGDAGPR 1215
Query: 367 AKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGL-PPREGRGMPPPLRGGPGGPGGPG 425
+E F G PP + G + P + G PP RG PG PG PG
Sbjct: 1216 GPTGIEGFPG----------------PP--GLPGAIIPGQTGNRGPPGSRGSPGAPGPPG 1257
Query: 426 GPMGRMGGRGGDRG--GFP-PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRT 482
P + G GD+G G P P+GP G+ G+ G + G P P G+ F
Sbjct: 1258 PPGSHVIGIKGDKGSMGHPGPKGPPGTAGDMGPPGRL-GAPGTPGLPGPR-GDPGFQGFP 1315
Query: 483 ECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG- 541
K GFL PP G G GP G+RG G L PG G G+ G
Sbjct: 1316 GVKGEKG--NPGFLGSIGPP--GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGM 1371
Query: 542 -GFRGGRGMDRGGFGGGRRGGPG-----GPPGPLMEQMGGRRGGRGGPG 584
G G G G RG PG G PGP E+ G +G +G PG
Sbjct: 1372 QGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEK--GNKGSKGEPG 1418
Score = 62.4 bits (150), Expect = 1e-09
Identities = 131/512 (25%), Positives = 159/512 (31%), Gaps = 79/512 (15%)
Query: 122 PAYPAYGQQPAATAPTSYSSTQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPP 181
P P P P P Q Q T G P + G G + P
Sbjct: 598 PGDPGSPGSPGPAGPAGPPGYGP----QGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTP 653
Query: 182 TSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGP 241
PP P P G G GF GP GP
Sbjct: 654 VPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGP------PGP 707
Query: 242 DNRGRGRGGFD--RGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPD 299
+G GF +G + G+ G G G G G +P M GP G P P
Sbjct: 708 ----KGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP----GTPGFPG 759
Query: 300 EDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKP--KGDA 357
E ++ G + + L L G ++ G P + G P +G
Sbjct: 760 ERGNS------GEHGEIGLPGLPGLPGTPGNEGLDGPRGDP-------GQPGPPGEQGPP 806
Query: 358 TVSYEDPPTAKAAVEWFDGKDFQGSKLKVS---------LARKKPPMNSMRGGLPPREGR 408
E P A+ K QG + K L R P + G+P +G
Sbjct: 807 GRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGE 866
Query: 409 GMPPPLRGGPGGPG--GPGGPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDW 466
P RG PG PG GP G G +G G G P GP G+ G P G+
Sbjct: 867 MGPLGQRGYPGNPGILGPPGEDGVIGMMGFP-GAIGPPGPPGNPGTPGQRGSPGIPGVKG 925
Query: 467 QCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRG 526
Q PG + Q P P GD+G G G G G +RG
Sbjct: 926 QRGTPGAKGE---------QGDKGNPG---PSEISHVIGDKGEPGLKGFAGNPGEKGNRG 973
Query: 527 GPGGMFRGGRGGDRG--GFRGGRGMDRGGFGG----GRRGGPGGPPGPLMEQMGGRRGGR 580
PG G G G G G RG D G G G RG PG M G+RG
Sbjct: 974 VPGMPGLKGLKGLPGPAGPPGPRG-DLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTL 1032
Query: 581 GGPGKM-------------DKGEHRQERRDRP 599
G PG+ DKGE RP
Sbjct: 1033 GFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRP 1064
Score = 62.0 bits (149), Expect = 2e-09
Identities = 107/374 (28%), Positives = 137/374 (36%), Gaps = 92/374 (24%)
Query: 237 SMSGPDNRGRGRGGFDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPV 296
+++GPDNR G G +G MG G G PG E + G P
Sbjct: 247 TLTGPDNR-----------TDLKGEKGDKGAMGEPGPPGPSGLPG----ESYGSEKGAPG 291
Query: 297 DPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGD 356
DP GL D + F GV K N+ G P + + D G+ KGD
Sbjct: 292 DP------------GLQGKPGKDGVPGFPGSEGV-KGNR--GFPGL-MGEDGIKGQ-KGD 334
Query: 357 ATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRG 416
PP + E++D +G + PP PR RG P G
Sbjct: 335 I-----GPPGFRGPTEYYDTYQEKGDE-----GTPGPP--------GPRGARGPQGP-SG 375
Query: 417 GPGGPGGPGGPMGRMGGRGGDRGGFPP-RGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGN 475
PG PG PG R G RG G+P +G +G RG P G + G +PGC
Sbjct: 376 PPGVPGSPGS--SRPGLRGAP--GWPGLKGSKGERGRP--GKDAMGTPG-----SPGCAG 424
Query: 476 QNFAWRTECNQCKAPKPEGFLPPPFPP--------PGGDRGRGGPGGMRGGRGGLMDRGG 527
+P G PP PP P GD G G G G G +G
Sbjct: 425 -------------SPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGE 471
Query: 528 PGGM-----FRGGRGGDRG--GFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGR 580
PG + + G G G G G +G+ G +G PG P + G G +
Sbjct: 472 PGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQ 531
Query: 581 GGPG-KMDKGEHRQ 593
G PG K +KGE Q
Sbjct: 532 GDPGLKGEKGETLQ 545
Score = 60.8 bits (146), Expect = 3e-09
Identities = 101/379 (26%), Positives = 132/379 (34%), Gaps = 98/379 (25%)
Query: 228 GFSGPGENRSMSGPDNRGRGRGGFDRGGMSRGGRG-------GGRGGMGSAGERGGFNKP 280
G GP ++SG + +G G S G G G +G G G +G P
Sbjct: 578 GLPGPKGELALSG-EKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAP 636
Query: 281 GGPMDEGPDLDL-------GPPVDPDEDSDNSAIYVQGLNDSVTLDDLADFFKQCGVVKM 333
G P + GP +L GPP P G+ S+ +CG +
Sbjct: 637 GPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSL---------GKCGDPGL 687
Query: 334 NKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLARKK- 392
G+P G + + PP K + F G+K + K
Sbjct: 688 PGPDGEP--------------GIPGIGFPGPPGPKG------DQGFPGTKGSLGCPGKMG 727
Query: 393 PPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGN 452
P + GLP +G P PGGPG PG P G+RG G G G
Sbjct: 728 EPGLPGKPGLPGAKGE----PAVAMPGGPGTPGFP--------GERGNSGEHGEIGLPGL 775
Query: 453 PSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPP---FPPPGGDRGR 509
P G + D +PG P P G PP P G +G
Sbjct: 776 PGLPGTPGNEGLDGPRGDPG----------------QPGPPGEQGPPGRCIEGPRGAQGL 819
Query: 510 GGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRGGRGMDRGGFGG--GRRGGPG--GP 565
G G++G +G R G+ G +G G G+DR GF G G G PG G
Sbjct: 820 PGLNGLKGQQG------------RRGKTGPKGD-PGIPGLDRSGFPGETGSPGIPGHQGE 866
Query: 566 PGPLMEQMGGRRGGRGGPG 584
GPL G+RG G PG
Sbjct: 867 MGPL-----GQRGYPGNPG 880
Score = 55.8 bits (133), Expect = 1e-07
Identities = 74/234 (31%), Positives = 91/234 (38%), Gaps = 63/234 (26%)
Query: 401 GLPPREG----RGMP--PPLRGGPGGPGGPG--GPMGRMG--GRGGDRG--GFP------ 442
GLP G RG+ P G PG PG PG GP G +G G G +G GFP
Sbjct: 82 GLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTL 141
Query: 443 -------PRGPRGSRGNPSGGGNVQHRA-GDWQCPNPGCGNQNFAWRTECNQCKAPKPEG 494
G +G +G P+ +++ A GD P G Q P P G
Sbjct: 142 GYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAP-GPQGL-----------PGPPG 189
Query: 495 FLPPPFPPPGGDRGRGGPGGM--RGGRGGLMDR-----------------GGPGGMFRGG 535
F P P PPG G PG M RG +G + +R G PG +
Sbjct: 190 F-PGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTL 248
Query: 536 RGGD-RGGFRGGRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDK 588
G D R +G +G D+G G GP G PG E G +G G PG K
Sbjct: 249 TGPDNRTDLKGEKG-DKGAMGEPGPPGPSGLPG---ESYGSEKGAPGDPGLQGK 298
Score = 52.8 bits (125), Expect = 9e-07
Identities = 55/172 (31%), Positives = 65/172 (37%), Gaps = 31/172 (18%)
Query: 391 KKPPMNSMRGGLPPREGR----GMPPPLRGGPGGPGGPG--GPMGRMGGRG--GDRGGFP 442
K PP + G P R G G+P P RG PG G PG G G G G G G
Sbjct: 1279 KGPPGTAGDMGPPGRLGAPGTPGLPGP-RGDPGFQGFPGVKGEKGNPGFLGSIGPPGPIG 1337
Query: 443 PRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPP 502
P+GP G RG+P + PG P +G PP PP
Sbjct: 1338 PKGPPGVRGDPGTLKIISLPGSPGPPGTPG----------------EPGMQGEPGPPGPP 1381
Query: 503 ----PGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG--GFRGGRG 548
P G RG+ G G G G ++G G G G G G +G RG
Sbjct: 1382 GNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRG 1433
Score = 46.2 bits (108), Expect = 9e-05
Identities = 61/190 (32%), Positives = 76/190 (40%), Gaps = 27/190 (14%)
Query: 415 RGGPGGPGGPGGPMGRMGGRGGDRGGFPPRGPRGSRGNP--SGGGNVQHRAG-DWQCPNP 471
+G PG PG PG G G G P+GP+G G P +G V+ +G +P
Sbjct: 51 KGFPGPPGSPG-----QKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSP 105
Query: 472 GC----GNQNFAWRTECNQCKAPKPE-GFLPPPFPPPGGDRGRGGPGGMRGGRGG----- 521
G GN C K E GF P P G G G G++G +G
Sbjct: 106 GLPGTPGNTGPYGLVGVPGCSGSKGEQGF--PGLPGTLGYPGIPGAAGLKGQKGAPAKEE 163
Query: 522 ---LMDRGGPGGMFRGGRGGDRG--GFRG--GRGMDRGGFGGGRRGGPGGPPGPLMEQMG 574
L +G PG G G G GF G G G FG GP GP G + E++
Sbjct: 164 DIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVI 223
Query: 575 GRRGGRGGPG 584
G +G RG G
Sbjct: 224 GHKGERGVKG 233
Score = 41.2 bits (95), Expect = 0.003
Identities = 82/323 (25%), Positives = 102/323 (31%), Gaps = 66/323 (20%)
Query: 159 GQPSSYGQQSSYGQQSSYGQQPPTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSS 218
G P S G G Q G P +TG P + + P
Sbjct: 1143 GFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGL 1202
Query: 219 MGVYGQ--ESG--------GFSGP---------GENRSMSGPDNRGRGRGGFDRG--GMS 257
G G ++G GF GP G+ + P +RG G G
Sbjct: 1203 PGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSH 1262
Query: 258 RGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDLGPPVDPDEDSDNSAIYVQGLNDSVT 317
G G +G MG G +G PG D GP LG P P QG
Sbjct: 1263 VIGIKGDKGSMGHPGPKG---PPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPG--- 1316
Query: 318 LDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGK 377
VK K + I G PKG V DP T K
Sbjct: 1317 -------------VKGEKGNPGFLGSIGPPGPIG-PKGPPGVR-GDPGTLKI-------- 1353
Query: 378 DFQGSKLKVSLARKKPPMNSMRGGLPPREGRGMPPPLRGGPGGPGGPGGPMGRMG--GRG 435
+SL P + G P +G PP GP G GP GP G+ G G+
Sbjct: 1354 --------ISLPGSPGPPGT--PGEPGMQGEPGPP----GPPGNLGPCGPRGKPGKDGKP 1399
Query: 436 GDRGGFPPRGPRGSRGNPSGGGN 458
G G +G +GS+G P G+
Sbjct: 1400 GTPGPAGEKGNKGSKGEPGPAGS 1422
Score = 32.3 bits (72), Expect = 1.3
Identities = 38/125 (30%), Positives = 48/125 (38%), Gaps = 27/125 (21%)
Query: 484 CNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRG-- 541
C+ K K E FP P G G+ G G G G +G PG G G RG
Sbjct: 41 CDGAKGEKGE----KGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGIS 96
Query: 542 ---GFRGGRGM-----DRGGFG-------GGRRGGPGGP--PG----PLMEQMGGRRGGR 580
GF G G+ + G +G G +G G P PG P + G +G +
Sbjct: 97 GLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQK 156
Query: 581 GGPGK 585
G P K
Sbjct: 157 GAPAK 161
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.135 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,967,005
Number of Sequences: 37866
Number of extensions: 2820260
Number of successful extensions: 56996
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 576
Number of HSP's successfully gapped in prelim test: 1141
Number of HSP's that attempted gapping in prelim test: 13213
Number of HSP's gapped (non-prelim): 14809
length of query: 600
length of database: 18,247,518
effective HSP length: 108
effective length of query: 492
effective length of database: 14,157,990
effective search space: 6965731080
effective search space used: 6965731080
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.