Guide to the Human Genome
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Search of human proteins with 239757639

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239757639 PREDICTED: similar to collagen, type I, alpha 2
[Homo sapiens]
         (2378 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239757639 PREDICTED: similar to collagen, type I, alpha 2 [Ho...  4566   0.0  
gi|239746652 PREDICTED: hypothetical protein [Homo sapiens]          2160   0.0  
gi|239752511 PREDICTED: hypothetical protein, partial [Homo sapi...   694   0.0  
gi|239746643 PREDICTED: hypothetical protein [Homo sapiens]           367   e-100
gi|239746650 PREDICTED: hypothetical protein [Homo sapiens]           362   2e-99
gi|239746623 PREDICTED: hypothetical protein [Homo sapiens]           359   2e-98
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...   125   6e-28
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...   125   6e-28
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]     114   1e-24
gi|48762934 alpha 2 type I collagen [Homo sapiens]                    100   2e-20
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...   100   2e-20
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...   100   3e-20
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...   100   3e-20
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...   100   3e-20
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    99   6e-20
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    99   6e-20
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          91   1e-17
gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]               88   1e-16
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       87   3e-16
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       85   1e-15
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]    83   3e-15
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      81   1e-14
gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]               77   2e-13
gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]     69   5e-11
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]                64   2e-09
gi|5803080 macrophage receptor with collagenous structure [Homo ...    59   4e-08
gi|11386161 alpha 2 type IX collagen [Homo sapiens]                    57   2e-07
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]      57   2e-07
gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]       57   3e-07
gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo ...    54   2e-06

>gi|239757639 PREDICTED: similar to collagen, type I, alpha 2 [Homo
            sapiens]
          Length = 2378

 Score = 4566 bits (11843), Expect = 0.0
 Identities = 2378/2378 (100%), Positives = 2378/2378 (100%)

Query: 1    MITTKHKRNQILQATSSEESLVHKDRGDGERPVNVRVVQVAPLRHESTPYEDTVHDIANE 60
            MITTKHKRNQILQATSSEESLVHKDRGDGERPVNVRVVQVAPLRHESTPYEDTVHDIANE
Sbjct: 1    MITTKHKRNQILQATSSEESLVHKDRGDGERPVNVRVVQVAPLRHESTPYEDTVHDIANE 60

Query: 61   DADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQ 120
            DADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQ
Sbjct: 61   DADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQ 120

Query: 121  GVANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKED 180
            GVANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKED
Sbjct: 121  GVANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKED 180

Query: 181  AAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVA 240
            AAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVA
Sbjct: 181  AAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVA 240

Query: 241  NEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQ 300
            NEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQ
Sbjct: 241  NEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQ 300

Query: 301  GIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANED 360
            GIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANED
Sbjct: 301  GIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANED 360

Query: 361  AAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGI 420
            AAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGI
Sbjct: 361  AAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGI 420

Query: 421  ANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAV 480
            ANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAV
Sbjct: 421  ANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAV 480

Query: 481  HGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANE 540
            HGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANE
Sbjct: 481  HGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANE 540

Query: 541  VAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGV 600
            VAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGV
Sbjct: 541  VAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGV 600

Query: 601  AIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDA 660
            AIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDA
Sbjct: 601  AIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDA 660

Query: 661  AQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIAN 720
            AQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIAN
Sbjct: 661  AQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIAN 720

Query: 721  EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQG 780
            EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQG
Sbjct: 721  EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQG 780

Query: 781  IAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDA 840
            IAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDA
Sbjct: 781  IAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDA 840

Query: 841  AQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVA 900
            AQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVA
Sbjct: 841  AQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVA 900

Query: 901  AQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANE 960
            AQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANE
Sbjct: 901  AQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANE 960

Query: 961  DAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGI 1020
            DAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGI
Sbjct: 961  DAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGI 1020

Query: 1021 ANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAA 1080
            ANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAA
Sbjct: 1021 ANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAA 1080

Query: 1081 QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHE 1140
            QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHE
Sbjct: 1081 QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHE 1140

Query: 1141 DAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1200
            DAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV
Sbjct: 1141 DAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1200

Query: 1201 AKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAA 1260
            AKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAA
Sbjct: 1201 AKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAA 1260

Query: 1261 HGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANE 1320
            HGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANE
Sbjct: 1261 HGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANE 1320

Query: 1321 VEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGI 1380
            VEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGI
Sbjct: 1321 VEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGI 1380

Query: 1381 ANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAA 1440
            ANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAA
Sbjct: 1381 ANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAA 1440

Query: 1441 HGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKP 1500
            HGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKP
Sbjct: 1441 HGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKP 1500

Query: 1501 DAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGV 1560
            DAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGV
Sbjct: 1501 DAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGV 1560

Query: 1561 VKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDA 1620
            VKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDA
Sbjct: 1561 VKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDA 1620

Query: 1621 AQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIAN 1680
            AQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIAN
Sbjct: 1621 AQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIAN 1680

Query: 1681 EDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHG 1740
            EDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHG
Sbjct: 1681 EDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHG 1740

Query: 1741 ITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDA 1800
            ITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDA
Sbjct: 1741 ITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDA 1800

Query: 1801 ARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAK 1860
            ARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAK
Sbjct: 1801 ARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAK 1860

Query: 1861 EDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQG 1920
            EDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQG
Sbjct: 1861 EDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQG 1920

Query: 1921 ISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDA 1980
            ISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDA
Sbjct: 1921 ISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDA 1980

Query: 1981 AQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIAN 2040
            AQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIAN
Sbjct: 1981 AQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIAN 2040

Query: 2041 EDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQD 2100
            EDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQD
Sbjct: 2041 EDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQD 2100

Query: 2101 AAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVA 2160
            AAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVA
Sbjct: 2101 AAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVA 2160

Query: 2161 NEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQ 2220
            NEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQ
Sbjct: 2161 NEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQ 2220

Query: 2221 GVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVHGIANED 2280
            GVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVHGIANED
Sbjct: 2221 GVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVHGIANED 2280

Query: 2281 AVYDIANDTVQGTLTRTLYRTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLM 2340
            AVYDIANDTVQGTLTRTLYRTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLM
Sbjct: 2281 AVYDIANDTVQGTLTRTLYRTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLM 2340

Query: 2341 RAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDTV 2378
            RAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDTV
Sbjct: 2341 RAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDTV 2378


>gi|239746652 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1513

 Score = 2160 bits (5596), Expect = 0.0
 Identities = 1166/1407 (82%), Positives = 1203/1407 (85%), Gaps = 129/1407 (9%)

Query: 1085 HEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQ 1144
            +ED V  IANEDA                D   G+ NEDAVQGVANEV  QGVA+EDA  
Sbjct: 123  YEDTVHDIANEDA----------------DAAHGITNEDAVQGVANEVAAQGVANEDAAH 166

Query: 1145 GIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEV 1204
            G+ANE AAHG+ANE AA G+ANE AAQG+ANEDAAQG+A+EDAVQG+ANEDA HG+A EV
Sbjct: 167  GVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEDAVQGVANEDAAHGIANEV 226

Query: 1205 AAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGIS 1264
            AAHGVANEDAA  +A  DAA+G+ANE A  G+A ED A G+A E  AHGV NE A  G+ 
Sbjct: 227  AAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVV 286

Query: 1265 KEDAVQGI-ANEDAAQGIAK-------------------------------EDAVQGIAN 1292
             ++A+ G+ ANEDAAQ IAK                               EDA  GI N
Sbjct: 287  NQEALHGVVANEDAAQAIAKPDSAHGIANEGVANEVAAQGIATEDVADGIAEDAAHGITN 346

Query: 1293 EDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQG 1352
            E+AAQ IAK+D    + NED +QGVANE    GVA+EDA QGIANE A HGI+ EDA QG
Sbjct: 347  EEAAQAIAKQDAAHSITNEDAVQGVANEDAAHGVANEDAAQGIANEVATHGISKEDAVQG 406

Query: 1353 IANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKE---------DPVQGVANEDA 1403
            IANEDAAQ IANEDAAQGI+ EDAVQGIANEDA  G+AKE         DPVQGVANEDA
Sbjct: 407  IANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDA 466

Query: 1404 VQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAH 1463
            VQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAH
Sbjct: 467  VQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAH 526

Query: 1464 EDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADG 1523
            EDAVQGIANEDAVHG+AKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIAT+DVADG
Sbjct: 527  EDAVQGIANEDAVHGIAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATQDVADG 586

Query: 1524 IANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDA 1583
            IANEDAAHGVANEVAA GIANEVAVH VAIEDA QGV KEVTAHGVANEDAVQGVVNE A
Sbjct: 587  IANEDAAHGVANEVAAHGIANEVAVHCVAIEDAAQGVAKEVTAHGVANEDAVQGVVNEYA 646

Query: 1584 LHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGIS 1643
            LHSVVANEDAAQAIAKPDAAHGIANEVAAHSIAN+DAAQGIAN+DAAQGIANEVAAHGIS
Sbjct: 647  LHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANEDAAQGIANEDAAQGIANEVAAHGIS 706

Query: 1644 KEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQ 1703
            KEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQ
Sbjct: 707  KEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQ 766

Query: 1704 GVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAH---------GIANED 1754
            GVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAH         GIANED
Sbjct: 767  GVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANED 826

Query: 1755 AAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIA 1814
            AAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIA
Sbjct: 827  AAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIA 886

Query: 1815 TEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQ 1874
            TEDVADGI NEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQ
Sbjct: 887  TEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQ 946

Query: 1875 GVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQD 1934
            GVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGI+KED VQG+AN+D
Sbjct: 947  GVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGIAKEDPVQGVANED 1006

Query: 1935 AAQGIAK------------------EDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIA 1976
              QG+A                   EDAVQGIANEDAA GIANEVAAHGIANEDAAQGIA
Sbjct: 1007 PVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIA 1066

Query: 1977 NEDAAQGIAHEDAVQGIANEDAV---------HGVANEDAAHAIAKPDAARGIANEVAAQ 2027
            NEDAAQGIAHEDAVQGIANEDAV         HGVANEDAAHAIAKPDAARGIANEVAAQ
Sbjct: 1067 NEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQ 1126

Query: 2028 GIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANE---------GIATEDVADG 2078
            GIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANE         GIATEDVADG
Sbjct: 1127 GIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADG 1186

Query: 2079 IAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAA 2138
            IAEDAVQGITNEEAAQAIAKQDAAHGIT EDAAQGVTNEVAAQGVANEDAAHGVANEVAA
Sbjct: 1187 IAEDAVQGITNEEAAQAIAKQDAAHGITNEDAAQGVTNEVAAQGVANEDAAHGVANEVAA 1246

Query: 2139 HGVANEDAAQGVANEVAAQ---------GVANEDAVQGVANEVEVQGIAHKDAIQGI--- 2186
            HGVANEDAAQGVANEVAAQ         GVANEDAVQGVANEVEVQGIAHKDAIQGI   
Sbjct: 1247 HGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANE 1306

Query: 2187 ------ANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGV 2240
                  ANEDAAQGVANEVAAHGVANEDAA GVANEVAAQGVANEDAAQGVANEVAVHGV
Sbjct: 1307 DAAQGVANEDAAQGVANEVAAHGVANEDAAHGVANEVAAQGVANEDAAQGVANEVAVHGV 1366

Query: 2241 ANEDAARHMAKEDAAQGIANEDAAHGIANEDAVH---------GIANEDAVYDIANDTVQ 2291
            ANEDAARHMAKEDAAQ IANEDAAHGIANEDAVH         GIANEDAVYDIANDTVQ
Sbjct: 1367 ANEDAARHMAKEDAAQDIANEDAAHGIANEDAVHGIANEDSVYGIANEDAVYDIANDTVQ 1426

Query: 2292 GTLTRTLYRTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMRAPYKTSPMRA 2351
            GTLTRTLYRTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMRAPYKTSPMRA
Sbjct: 1427 GTLTRTLYRTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMRAPYKTSPMRA 1486

Query: 2352 LYTTLLMIPTRHANADTVHDIANEDTV 2378
            LYTTLLMIPTRHANADTVHDIANEDTV
Sbjct: 1487 LYTTLLMIPTRHANADTVHDIANEDTV 1513



 Score = 1807 bits (4680), Expect = 0.0
 Identities = 971/1330 (73%), Positives = 1047/1330 (78%), Gaps = 54/1330 (4%)

Query: 467  HEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVAD 526
            +ED V  IANEDA                DAAH I   DA +G+ANEVAAQG+A ED A 
Sbjct: 123  YEDTVHDIANEDA----------------DAAHGITNEDAVQGVANEVAAQGVANEDAAH 166

Query: 527  GIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANED 586
            G+ANE A HGVANE AA GVANE AA  +A  DAA G+ANE A QG+A ED A GIANE 
Sbjct: 167  GVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEDAVQGVANEDAAHGIANEV 226

Query: 587  AAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVV 646
            AAHGVANE A  GVA EDA QGVANEDAVHGVANEDAAQG+AKEVTAHGV NEDAVQGVV
Sbjct: 227  AAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVV 286

Query: 647  NEDALHGVVANEDAAQAIAKPDAAHGIANE-----VAAHGIANEDAAQGIANEDAAQGIA 701
            N++ALHGVVANEDAAQAIAKPD+AHGIANE     VAA GIA ED A GIA EDAA GI 
Sbjct: 287  NQEALHGVVANEDAAQAIAKPDSAHGIANEGVANEVAAQGIATEDVADGIA-EDAAHGIT 345

Query: 702  NEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQ 761
            NE AA  I+K+DA   I NEDA QG+A+EDA  G+ANEDA  G+A EVA HG++ ED VQ
Sbjct: 346  NEEAAQAIAKQDAAHSITNEDAVQGVANEDAAHGVANEDAAQGIANEVATHGISKEDAVQ 405

Query: 762  GVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANED 821
            G+ANED  QG+ANE   QGIAHEDAVQGIANEDA HG+A EVAAHGVANED  QGVANED
Sbjct: 406  GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANED 465

Query: 822  AAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAI 881
            A QGVANE  V GVA+EDA QG+A E  AHG+ NE A  G+ NE+A  G+ ANEDAAQ I
Sbjct: 466  AVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGI-ANEDAAQGI 524

Query: 882  AKPDAAHGIANE----GVANEVAAQGIATEDVADGIAK-DAAHGITKEEAAQAIAKQDAA 936
            A  DA  GIANE    G+A EVAA G+A ED A  IAK DAA GI  E A Q IA QD A
Sbjct: 525  AHEDAVQGIANEDAVHGIAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATQDVA 584

Query: 937  HSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANE 996
              I NEDAA GVANE AAHG+ANE A   VA E AAQGVA E   HGVANEDAVQGV NE
Sbjct: 585  DGIANEDAAHGVANEVAAHGIANEVAVHCVAIEDAAQGVAKEVTAHGVANEDAVQGVVNE 644

Query: 997  VEVQGI-AHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHG 1055
              +  + A++DA Q IA  DAAHGIANEVAAH IANEDAAQGIANEDAAQGIANEVAAHG
Sbjct: 645  YALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANEDAAQGIANEDAAQGIANEVAAHG 704

Query: 1056 ISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDP 1115
            ISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDP
Sbjct: 705  ISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDP 764

Query: 1116 VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIAN 1175
            VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGI NEVAAHGIANEDAAQGIAN
Sbjct: 765  VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAN 824

Query: 1176 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQG 1235
            EDAAQGIAHEDAVQGIANEDAVH VAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQG
Sbjct: 825  EDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQG 884

Query: 1236 IATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDA 1295
            IATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKED +QG+ANE  
Sbjct: 885  IATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVE 944

Query: 1296 AQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIAN 1355
             QG+A ED VQG+ANED   G+ANE   QG+A+EDA Q IANEDAA GIA ED  QG+AN
Sbjct: 945  VQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGIAKEDPVQGVAN 1004

Query: 1356 EDAAQDIANEDAAQGISK---------EDAVQGIANEDAAQGIAKEDPVQGVANEDAVQG 1406
            ED  Q +ANEDA QG++          EDAVQGIANEDAA GIA E    G+ANEDA QG
Sbjct: 1005 EDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQG 1064

Query: 1407 VANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDA 1466
            +ANE   QG+AHEDAVQGIANEDA HG+A EVAAHG+ANEDAA  IA  DAA+GIA+E A
Sbjct: 1065 IANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVA 1124

Query: 1467 VQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGI-----ANEVATQGIATEDVA 1521
             QGIA ED   G+A E AAHGVANEDAA AIAKPDAA GI     ANEVA QGIATEDVA
Sbjct: 1125 AQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVA 1184

Query: 1522 DGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNE 1581
            DGIA EDA  G+ NE AAQ IA + A HG+  EDA QGV  EV A GVANEDA  GV NE
Sbjct: 1185 DGIA-EDAVQGITNEEAAQAIAKQDAAHGITNEDAAQGVTNEVAAQGVANEDAAHGVANE 1243

Query: 1582 DALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHG 1641
             A H  VANEDAAQ         G+ANEVAA  +AN+DA  G+AN+DA QG+ANEV   G
Sbjct: 1244 VAAHG-VANEDAAQ---------GVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQG 1293

Query: 1642 ISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDP 1701
            I+ +DA+QGIANEDAAQG+ANEDAAQG+A+E A  G+ANEDA HGVA EVAA GVANED 
Sbjct: 1294 IAHKDAIQGIANEDAAQGVANEDAAQGVANEVAAHGVANEDAAHGVANEVAAQGVANEDA 1353

Query: 1702 VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAH 1761
             QGVANE AV GVANE   + +A EDA Q IANEDAAHGI NE A HGIANED+  GIA+
Sbjct: 1354 AQGVANEVAVHGVANEDAARHMAKEDAAQDIANEDAAHGIANEDAVHGIANEDSVYGIAN 1413

Query: 1762 EDAVQGIANE 1771
            EDAV  IAN+
Sbjct: 1414 EDAVYDIAND 1423



 Score = 1613 bits (4177), Expect = 0.0
 Identities = 896/1341 (66%), Positives = 966/1341 (72%), Gaps = 222/1341 (16%)

Query: 16   SSEESLVHKDRGDGERPVNVRVVQVAPLRHESTPYEDTVHDIANEDADAAHGITNEDAVQ 75
            +SEESLVHKDRGDGERPVNVRVVQVAPLRHESTPYEDTVHDIANEDADAAHGITNEDAVQ
Sbjct: 89   ASEESLVHKDRGDGERPVNVRVVQVAPLRHESTPYEDTVHDIANEDADAAHGITNEDAVQ 148

Query: 76   GVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANED 135
            GVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDA QGVANED
Sbjct: 149  GVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANED 208

Query: 136  AVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQGIS 195
            AVQGVANEDA  GIANE AAHG+ANEDAAQG+ANEDAAQ +A EDA   +ANEDAAQG++
Sbjct: 209  AVQGVANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVA 268

Query: 196  K---------EDAVQG----------IANEDAAQGIAKEDPVQGVANE------------ 224
            K         EDAVQG          +ANEDAAQ IAK D   G+ANE            
Sbjct: 269  KEVTAHGVTNEDAVQGVVNQEALHGVVANEDAAQAIAKPDSAHGIANEGVANEVAAQGIA 328

Query: 225  ----------------------------DPVQGVANEDAVQGVANEVEVQGVAHEDAVQG 256
                                        D    + NEDAVQGVANE    GVA+EDA QG
Sbjct: 329  TEDVADGIAEDAAHGITNEEAAQAIAKQDAAHSITNEDAVQGVANEDAAHGVANEDAAQG 388

Query: 257  IANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVA 316
            IANE A HGI+ E A  GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVA
Sbjct: 389  IANEVATHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVA 448

Query: 317  AHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKEVTAHGVAN 376
            AHGVANED    +A  DA  G+ANEV  QG+A ED   GIANEDAAHG+A EV AHG+AN
Sbjct: 449  AHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIAN 508

Query: 377  ------------------EDAVQGVVNEDALHGV--------VANEDAAQAIAKPDAAHG 410
                              EDAVQG+ NEDA+HG+        VANEDAA AIAKPDAA G
Sbjct: 509  EDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGIAKEVAAHGVANEDAAHAIAKPDAARG 568

Query: 411  IANEVA---------AHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDA 461
            IANEVA         A GIANEDAA G+ANEVAAHGI+ E AV  +A EDAAQG+A E  
Sbjct: 569  IANEVATQGIATQDVADGIANEDAAHGVANEVAAHGIANEVAVHCVAIEDAAQGVAKEVT 628

Query: 462  AQGIAHEDAVQGIANE-------------------DAVHGVAKEVAAHGVANKDAAHAIA 502
            A G+A+EDAVQG+ NE                   DA HG+A EVAAH +AN+DAA  IA
Sbjct: 629  AHGVANEDAVQGVVNEYALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANEDAAQGIA 688

Query: 503  KPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAH 562
              DAA+GIANEVAA GI+ ED   GIANEDA  G+ANE AA G+A+EDA   IA  DA H
Sbjct: 689  NEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVH 748

Query: 563  GIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANED--------- 613
            G+A EVA  G+A ED   G+ANEDA  GVANEV V GVA EDAVQG+ANED         
Sbjct: 749  GVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEV 808

Query: 614  AVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGV--------VANEDAAQAIA 665
            A HG+ANEDAAQGIA E  A G+A+EDAVQG+ NEDA+H V        VANEDAA AIA
Sbjct: 809  AAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIA 868

Query: 666  KPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQ 725
            KPDAA GIANEVAA GIA ED A GIANEDAA G+ANEVAAHGISKEDAVQGIANEDAAQ
Sbjct: 869  KPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQ 928

Query: 726  GI------------------AHEDAVQGIANEDAVHGVAKEVAA---------------- 751
            GI                  AHEDAVQGIANEDA HG+A E AA                
Sbjct: 929  GIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANED 988

Query: 752  -----------HGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIA 800
                        GVANEDPVQGVANED VQGVANEVEVQG+AHEDAVQGIANEDAAHGIA
Sbjct: 989  AAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIA 1048

Query: 801  NEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDA-- 858
            NEVAAHG+ANEDAAQG+ANEDAAQG+A+EDAV G+ANEDA  GVAKEV AHGV NEDA  
Sbjct: 1049 NEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAH 1108

Query: 859  -------------------------VQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANE 893
                                       G+ NE+A HG VANEDAAQAIAKPDAAHGIANE
Sbjct: 1109 AIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHG-VANEDAAQAIAKPDAAHGIANE 1167

Query: 894  GVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQ------- 946
            GVANEVAAQGIATEDVADGIA+DA  GIT EEAAQAIAKQDAAH ITNEDAAQ       
Sbjct: 1168 GVANEVAAQGIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITNEDAAQGVTNEVA 1227

Query: 947  -----------GVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVAN 995
                       GVANE AAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVAN
Sbjct: 1228 AQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVAN 1287

Query: 996  EVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHG 1055
            EVEVQGIAHKDAIQGIANEDAA G+ANE AA G+ANE AA G+ANEDAA G+ANEVAA G
Sbjct: 1288 EVEVQGIAHKDAIQGIANEDAAQGVANEDAAQGVANEVAAHGVANEDAAHGVANEVAAQG 1347

Query: 1056 ISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDP 1115
            ++ EDA QG+ANE A  G+ANEDAA+ +A EDA Q IANEDA HG+A E A HG+ANED 
Sbjct: 1348 VANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQDIANEDAAHGIANEDAVHGIANEDS 1407

Query: 1116 VQGVANEDAVQGVANEVEVQG 1136
            V G+ANEDAV  +AN+  VQG
Sbjct: 1408 VYGIANEDAVYDIANDT-VQG 1427



 Score = 1278 bits (3308), Expect = 0.0
 Identities = 698/1055 (66%), Positives = 774/1055 (73%), Gaps = 114/1055 (10%)

Query: 1324 QGVAHEDAVQGIANE--DAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIA 1381
            +   +ED V  IANE  DAAHGI NEDA QG+ANE AAQ +ANEDAA G++ E A  G+A
Sbjct: 119  ESTPYEDTVHDIANEDADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVA 178

Query: 1382 NEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAH 1441
            NEDAAQG+A E   QGVANEDA QGVAN         EDAVQG+ANEDAAHGIANEVAAH
Sbjct: 179  NEDAAQGVANEVAAQGVANEDAAQGVAN---------EDAVQGVANEDAAHGIANEVAAH 229

Query: 1442 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHG-------------- 1487
            G+ANEDAAQG+ANEDAAQG+A+EDAV G+ANEDA  GVAKEV AHG              
Sbjct: 230  GVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNQE 289

Query: 1488 -----VANEDAAHAIAKPDAARGI-----ANEVATQGIATEDVADGIANEDAAHGVANEV 1537
                 VANEDAA AIAKPD+A GI     ANEVA QGIATEDVADGIA EDAAHG+ NE 
Sbjct: 290  ALHGVVANEDAAQAIAKPDSAHGIANEGVANEVAAQGIATEDVADGIA-EDAAHGITNEE 348

Query: 1538 AA------------------QGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVV 1579
            AA                  QG+ANE A HGVA EDA QG+  EV  HG++ EDAVQG+ 
Sbjct: 349  AAQAIAKQDAAHSITNEDAVQGVANEDAAHGVANEDAAQGIANEVATHGISKEDAVQGIA 408

Query: 1580 NEDALHSV--------VANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQ 1631
            NEDA   +        +A+EDA Q IA  DA HG+A EVAAH +AN+D  QG+AN+DA Q
Sbjct: 409  NEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQ 468

Query: 1632 GIANEV------------------AAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHED 1673
            G+ANEV                  AAHGI+ E A  GIANEDAAQGIANEDAAQGIAHED
Sbjct: 469  GVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHED 528

Query: 1674 AVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIA 1733
            AVQGIANEDAVHG+AKEVAAHGVANED    +A  DA +G+ANEV  QG+A +D   GIA
Sbjct: 529  AVQGIANEDAVHGIAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATQDVADGIA 588

Query: 1734 NEDAAHGITNEVAAHGIAN---------EDAAQGIAHEDAVQGIANEDAVHSVAKEVAAH 1784
            NEDAAHG+ NEVAAHGIAN         EDAAQG+A E    G+ANEDAV  V  E A H
Sbjct: 589  NEDAAHGVANEVAAHGIANEVAVHCVAIEDAAQGVAKEVTAHGVANEDAVQGVVNEYALH 648

Query: 1785 G-VANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKE 1843
              VANEDAA AIAKPDAA GIANEVAA  IA ED A GI NEDAA G+ANEVAAHGISKE
Sbjct: 649  SVVANEDAAQAIAKPDAAHGIANEVAAHSIANEDAAQGIANEDAAQGIANEVAAHGISKE 708

Query: 1844 DAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGI 1903
            DAVQGIANEDAAQGIA ED           QG+AHEDAVQGIANEDA HG+A E AA G+
Sbjct: 709  DAVQGIANEDAAQGIANED---------AAQGIAHEDAVQGIANEDAVHGVAKEVAAHGV 759

Query: 1904 ANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAA 1963
            ANED  Q +ANEDA QG++ E  VQG+A++DA QGIA EDA  GI NE AA GIANE AA
Sbjct: 760  ANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAA 819

Query: 1964 HGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANE 2023
             GIANEDAAQGIA+EDA QGIA+EDAV  +A E A HGVANEDAAHAIAKPDAARGIANE
Sbjct: 820  QGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANE 879

Query: 2024 VAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIA-ED 2082
            VAAQGIATEDVADGIANEDAAHGVANE AA  I+K DA  GIAN     ED A GIA ED
Sbjct: 880  VAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIAN-----EDAAQGIAKED 934

Query: 2083 AVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVA 2142
             +QG+ NE   Q +A +DA  GI  EDAA G+ NE AAQG+ANEDAA  +ANE AA G+A
Sbjct: 935  PIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGIA 994

Query: 2143 NEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAH 2202
             ED  QGVANE   QGVANEDAVQGVANEVEVQG+AH+DA+QGIANEDAA G+ANEVAAH
Sbjct: 995  KEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAH 1054

Query: 2203 GVANEDAAQGVANEVAAQGVANEDAAQGVAN---------EVAVHGVANEDAARHMAKED 2253
            G+ANEDAAQG+ANE AAQG+A+EDA QG+AN         EVA HGVANEDAA  +AK D
Sbjct: 1055 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPD 1114

Query: 2254 AAQGIANEDAAHGIANEDAVHGIANEDAVYDIAND 2288
            AA+GIANE AA GIA ED   GIANEDA + +AN+
Sbjct: 1115 AARGIANEVAAQGIATEDVADGIANEDAAHGVANE 1149



 Score = 1120 bits (2896), Expect = 0.0
 Identities = 620/900 (68%), Positives = 673/900 (74%), Gaps = 102/900 (11%)

Query: 51   EDTVHDIANEDA-------DAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHG 103
            E   H +ANEDA       DAA GI NE A QG+A +  A G+ANEDAAHGVANEVAAHG
Sbjct: 545  EVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATQDVADGIANEDAAHGVANEVAAHG 604

Query: 104  VANE---------DAAQGVANEVAAQGVANEDAVQGV----------ANEDAVQGVANED 144
            +ANE         DAAQGVA EV A GVANEDAVQGV          ANEDA Q +A  D
Sbjct: 605  IANEVAVHCVAIEDAAQGVAKEVTAHGVANEDAVQGVVNEYALHSVVANEDAAQAIAKPD 664

Query: 145  AVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKE------------------DAAQDIA 186
            A  GIANE AAH IANEDAAQGIANEDAAQ IA E                  DAAQ IA
Sbjct: 665  AAHGIANEVAAHSIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIA 724

Query: 187  NEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQ 246
            NEDAAQGI+ EDAVQGIANEDA  G+AKE    GVANEDPVQGVANEDAVQGVANEVEVQ
Sbjct: 725  NEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQ 784

Query: 247  GVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 306
            GVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED
Sbjct: 785  GVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 844

Query: 307  AVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVA 366
            AVH VAKEVAAHGVANEDAAHAIAKPDAA GIANEVA QGIATEDVADGIANEDAAHGVA
Sbjct: 845  AVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVA 904

Query: 367  KEVTAHGVANEDAVQGVVNEDALHGV-----------------VANEDAAQAIAKPDAAH 409
             EV AHG++ EDAVQG+ NEDA  G+                 VA+EDA Q IA  DAAH
Sbjct: 905  NEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAH 964

Query: 410  GIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHED 469
            GIANE AA GIANEDAAQ IANE AA GI+KED VQG+ANED  QG+A+EDA QG+A+E 
Sbjct: 965  GIANEDAAQGIANEDAAQDIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEV 1024

Query: 470  AVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIA 529
             VQG+A+EDAV G+A E AAHG+AN+ AAH IA  DAA+GIANE AAQGIA ED   GIA
Sbjct: 1025 EVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIA 1084

Query: 530  NEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAH 589
            NEDAVHGVA EVAAHGVANEDAAHAIAKPDAA GIANEVA QGIATEDVADGIANEDAAH
Sbjct: 1085 NEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAH 1144

Query: 590  GVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNE- 648
            GVANE A   +A  DA  G+ANE    GVANE AAQGIA E  A G+A EDAVQG+ NE 
Sbjct: 1145 GVANEDAAQAIAKPDAAHGIANE----GVANEVAAQGIATEDVADGIA-EDAVQGITNEE 1199

Query: 649  --------DALHGV--------VANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIA 692
                    DA HG+        V NE AAQ +A  DAAHG+ANEVAAHG+ANEDAAQG+A
Sbjct: 1200 AAQAIAKQDAAHGITNEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVA 1259

Query: 693  NEDAAQGIANEVAAHGISKEDAVQGIANE---------DAAQGIAHEDAVQGIANEDAVH 743
            NE AAQG+ANE A HG++ EDAVQG+ANE         DA QGIA+EDA QG+ANEDA  
Sbjct: 1260 NEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEDAAQ 1319

Query: 744  GVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEV 803
            GVA EVAAHG         VANED   GVANEV  QG+A+EDA QG+ANE A HG+ANE 
Sbjct: 1320 GVANEVAAHG---------VANEDAAHGVANEVAAQGVANEDAAQGVANEVAVHGVANED 1370

Query: 804  AAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVV 863
            AA  +A EDAAQ +ANEDAA G+ANEDAVHG+ANED+  G+A E   + + N D VQG +
Sbjct: 1371 AARHMAKEDAAQDIANEDAAHGIANEDAVHGIANEDSVYGIANEDAVYDIAN-DTVQGTL 1429



 Score =  299 bits (766), Expect = 2e-80
 Identities = 162/242 (66%), Positives = 180/242 (74%), Gaps = 25/242 (10%)

Query: 51   EDTVHDIANEDA-------DAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHG 103
            ED V  I NE+A       DAAHGITNEDA QGV NEVAAQGVANEDAAHGVANEVAAHG
Sbjct: 1189 EDAVQGITNEEAAQAIAKQDAAHGITNEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHG 1248

Query: 104  VANEDAAQGVANEVAAQGVANEDAVQGVANEDAVQGV------------------ANEDA 145
            VANEDAAQGVANEVAAQGVANEDAV GVANEDAVQGV                  ANEDA
Sbjct: 1249 VANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDA 1308

Query: 146  VQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQGISKEDAVQGIAN 205
             QG+ANEDAA G+ANE AA G+ANEDAA  +A E AAQ +ANEDAAQG++ E AV G+AN
Sbjct: 1309 AQGVANEDAAQGVANEVAAHGVANEDAAHGVANEVAAQGVANEDAAQGVANEVAVHGVAN 1368

Query: 206  EDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHG 265
            EDAA+ +AKED  Q +ANED   G+ANEDAV G+ANE  V G+A+EDAV  IAN+     
Sbjct: 1369 EDAARHMAKEDAAQDIANEDAAHGIANEDAVHGIANEDSVYGIANEDAVYDIANDTVQGT 1428

Query: 266  IT 267
            +T
Sbjct: 1429 LT 1430



 Score =  191 bits (485), Expect = 7e-48
 Identities = 123/245 (50%), Positives = 136/245 (55%), Gaps = 60/245 (24%)

Query: 51   EDTVHDIANEDADAA-------HGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHG 103
            ED VH +ANEDA           GI ++DA+QG+ANE AAQGVANEDAA GVANEVAAHG
Sbjct: 1270 EDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEDAAQGVANEVAAHG 1329

Query: 104  VANEDAAQGVANEVAAQGVANEDAVQGVANEDAVQGVANEDAV---------QGIANEDA 154
            VANEDAA GVANEVAAQGVANEDA QGVANE AV GVANEDA          Q IANEDA
Sbjct: 1330 VANEDAAHGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQDIANEDA 1389

Query: 155  AHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQGIS------------------- 195
            AHGIANEDA  GIANED+   IA EDA  DIAN D  QG                     
Sbjct: 1390 AHGIANEDAVHGIANEDSVYGIANEDAVYDIAN-DTVQGTLTRTLYRTSLMRTPYKASVM 1448

Query: 196  -------------KEDAVQGIANEDAAQGIAKEDPVQGV-----------ANEDPVQGVA 231
                         K    + +      +   K  P++ +           AN D V  +A
Sbjct: 1449 RTLYTTSLTRTPYKPSLTRTLYTTSLMRAPYKTSPMRALYTTLLMIPTRHANADTVHDIA 1508

Query: 232  NEDAV 236
            NED V
Sbjct: 1509 NEDTV 1513


>gi|239752511 PREDICTED: hypothetical protein, partial [Homo sapiens]
          Length = 609

 Score =  694 bits (1792), Expect = 0.0
 Identities = 383/616 (62%), Positives = 425/616 (68%), Gaps = 30/616 (4%)

Query: 1212 EDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQG 1271
            ED  H IA  DA   IA E A   IA ED   GIA EDAA G+ANE A H I+ EDA   
Sbjct: 13   EDTVHDIANEDAVYDIATEDAIYDIANEDAVQGIAKEDAAQGIANEEAVHDIANEDAAHV 72

Query: 1272 IANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDA 1331
            IANEDAAQ IA EDAV  IANEDA QGI  ED    +ANED   GVANEV         A
Sbjct: 73   IANEDAAQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEV---------A 123

Query: 1332 VQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAK 1391
             QG+ANEDA H IANEDAAQGIANEDAA  IANEDAAQ I+ EDA Q IANEDAAQGI+K
Sbjct: 124  AQGVANEDAVHCIANEDAAQGIANEDAAHGIANEDAAQDIANEDAAQDIANEDAAQGISK 183

Query: 1392 EDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQG 1451
            ED VQG+ANEDA QG+A E  VQGVA+ED VQG+ANEDA  GIA E         D  QG
Sbjct: 184  EDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGIAKE---------DPVQG 234

Query: 1452 IANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVA 1511
            +ANED  QG+A+EDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVA
Sbjct: 235  VANEDPVQGVANEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVA 294

Query: 1512 TQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVAN 1571
             QGIATEDVADGIANEDAAHGVANEVAAQG+ANE AV GVA EDA QGV KEVTAHGVAN
Sbjct: 295  AQGIATEDVADGIANEDAAHGVANEVAAQGVANEDAVEGVANEDAAQGVAKEVTAHGVAN 354

Query: 1572 EDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQ 1631
            EDAVQGVVNEDALH VVANEDAAQAIAKPDAAHGIANEV A  IAN+ A   IA +D   
Sbjct: 355  EDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVTAQGIANEVAIHSIAIEDTTP 414

Query: 1632 GIA-----------NEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIAN 1680
              A             ++     +   +  +        ++       +    +   +  
Sbjct: 415  SRAWLTRSLPRASLPRMSPTASLRTPPMASLTRRPPRPSLSRMPPTASLTRTPSRASLTR 474

Query: 1681 EDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHG 1740
                  + +      +    P   +      +GVANEVEVQG+AH+DA+QGIANEDAAHG
Sbjct: 475  SPPRASLTRTPPTASLTRSPPTASLTRTPP-RGVANEVEVQGIAHKDAIQGIANEDAAHG 533

Query: 1741 ITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDA 1800
            I NEVAAHGIANEDAAQGIA+EDA QGIANE A H ++KE    G+ANEDAA  IAK + 
Sbjct: 534  IANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDTVQGIANEDAAQGIAKENP 593

Query: 1801 ARGIANEVAAQGIATE 1816
             +G+ANE   QG+A E
Sbjct: 594  VQGVANEDPVQGVANE 609



 Score =  681 bits (1758), Expect = 0.0
 Identities = 380/617 (61%), Positives = 421/617 (68%), Gaps = 39/617 (6%)

Query: 278 EDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHG 337
           ED    IANEDA   IA EDA+  IANEDAV G+AKE AA G+ANE+A H IA  DAAH 
Sbjct: 13  EDTVHDIANEDAVYDIATEDAIYDIANEDAVQGIAKEDAAQGIANEEAVHDIANEDAAHV 72

Query: 338 IANEVATQGIATEDVADGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANED 397
           IANE A Q IA ED    IANEDA  G+  E  AH +ANEDA  GV NE A  GV ANED
Sbjct: 73  IANEDAAQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVAAQGV-ANED 131

Query: 398 AAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIA 457
           A   IA  DAA GIANE AAHGIANEDAAQ IANE AA  I+ EDA QGI+ EDA QGIA
Sbjct: 132 AVHCIANEDAAQGIANEDAAHGIANEDAAQDIANEDAAQDIANEDAAQGISKEDAVQGIA 191

Query: 458 HEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQ 517
           +EDAAQGIA ED VQG+ANED V GVA         N+DA   IAK D  +G+ANE   Q
Sbjct: 192 NEDAAQGIAKEDPVQGVANEDPVQGVA---------NEDAVQGIAKEDPVQGVANEDPVQ 242

Query: 518 GIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATED 577
           G+A ED   GIANEDAVHGVA EVAAHGVANEDAAHAIAKPDAA GIANEVA QGIATED
Sbjct: 243 GVANEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATED 302

Query: 578 VADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVA 637
           VADGIANEDAAHGVANEVA          QGVANEDAV GVANEDAAQG+AKEVTAHGVA
Sbjct: 303 VADGIANEDAAHGVANEVAA---------QGVANEDAVEGVANEDAAQGVAKEVTAHGVA 353

Query: 638 NEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAA 697
           NEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEV A GIANE A   IA ED  
Sbjct: 354 NEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVTAQGIANEVAIHSIAIEDTT 413

Query: 698 QGIA-----------NEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVA 746
              A             ++     +   +  +        ++       +    +   + 
Sbjct: 414 PSRAWLTRSLPRASLPRMSPTASLRTPPMASLTRRPPRPSLSRMPPTASLTRTPSRASLT 473

Query: 747 KEVAAHGVANEDPVQGVANEDVV--------QGVANEVEVQGIAHEDAVQGIANEDAAHG 798
           +      +    P   +              +GVANEVEVQGIAH+DA+QGIANEDAAHG
Sbjct: 474 RSPPRASLTRTPPTASLTRSPPTASLTRTPPRGVANEVEVQGIAHKDAIQGIANEDAAHG 533

Query: 799 IANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDA 858
           IANEVAAHG+ANEDAAQG+ANEDAAQG+ANE A HG++ ED  QG+A E  A G+  E+ 
Sbjct: 534 IANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDTVQGIANEDAAQGIAKENP 593

Query: 859 VQGVVNEEALHGVVANE 875
           VQGV NE+ + G VANE
Sbjct: 594 VQGVANEDPVQG-VANE 609



 Score =  647 bits (1668), Expect = 0.0
 Identities = 361/632 (57%), Positives = 414/632 (65%), Gaps = 63/632 (9%)

Query: 933  QDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQG 992
            +D  H I NEDA   +A EDA + +ANEDA QG+A E AAQG+ANE+AVH +ANEDA   
Sbjct: 13   EDTVHDIANEDAVYDIATEDAIYDIANEDAVQGIAKEDAAQGIANEEAVHDIANEDAAHV 72

Query: 993  VANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVA 1052
            +ANE         DA Q IANEDA H IANE A  GI NEDAA  IANEDAA G+ANEVA
Sbjct: 73   IANE---------DAAQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVA 123

Query: 1053 AHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVAN 1112
            A G++ EDAV  IANEDAAQGIANEDAA GIA+EDA Q IANEDA   +A E AA G++ 
Sbjct: 124  AQGVANEDAVHCIANEDAAQGIANEDAAHGIANEDAAQDIANEDAAQDIANEDAAQGISK 183

Query: 1113 EDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQG 1172
            ED VQG+ANEDA QG+A E  VQGVA+ED VQG+ANEDA  GIA E         D  QG
Sbjct: 184  EDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGIAKE---------DPVQG 234

Query: 1173 IANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVA 1232
            +ANED  QG+A+EDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVA
Sbjct: 235  VANEDPVQGVANEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVA 294

Query: 1233 AQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIAN 1292
            AQGIATEDVADGIANEDAAHGVANEVAA G++ EDAV+G+ANEDAAQG+AKE    G+AN
Sbjct: 295  AQGIATEDVADGIANEDAAHGVANEVAAQGVANEDAVEGVANEDAAQGVAKEVTAHGVAN 354

Query: 1293 EDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQG 1352
            EDA         VQGV NED + GV        VA+EDA Q IA  DAAHGIANE  AQG
Sbjct: 355  EDA---------VQGVVNEDALHGV--------VANEDAAQAIAKPDAAHGIANEVTAQG 397

Query: 1353 IANEDAAQDIANEDAAQGIS--------------------KEDAVQGIANEDAAQGIAKE 1392
            IANE A   IA ED     +                    +   +  +        +++ 
Sbjct: 398  IANEVAIHSIAIEDTTPSRAWLTRSLPRASLPRMSPTASLRTPPMASLTRRPPRPSLSRM 457

Query: 1393 DPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAA--------HGIANEVAAHGIA 1444
             P   +    +   +        +        +               G+ANEV   GIA
Sbjct: 458  PPTASLTRTPSRASLTRSPPRASLTRTPPTASLTRSPPTASLTRTPPRGVANEVEVQGIA 517

Query: 1445 NEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAR 1504
            ++DA QGIANEDAA GIA+E A  GIANEDA  G+A E AA G+ANE AAH I+K D  +
Sbjct: 518  HKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDTVQ 577

Query: 1505 GIANEVATQGIATEDVADGIANEDAAHGVANE 1536
            GIANE A QGIA E+   G+ANED   GVANE
Sbjct: 578  GIANEDAAQGIAKENPVQGVANEDPVQGVANE 609



 Score =  642 bits (1657), Expect = 0.0
 Identities = 360/621 (57%), Positives = 408/621 (65%), Gaps = 59/621 (9%)

Query: 48  TPYEDTVHDIANEDADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANE 107
           +PYEDTVHDIANEDA   + I  EDA+  +ANE A QG+A EDAA G+ANE A H +ANE
Sbjct: 10  SPYEDTVHDIANEDA--VYDIATEDAIYDIANEDAVQGIAKEDAAQGIANEEAVHDIANE 67

Query: 108 DAAQGVANEVAAQGVANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGI 167
           DAA  +ANE AAQ +ANEDAV  +ANEDA QG+ NEDA   IANEDAAHG+ANE AAQG+
Sbjct: 68  DAAHVIANEDAAQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVAAQGV 127

Query: 168 ANEDAAQDIAKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPV 227
           ANEDA   IA EDAAQ IANEDAA GI+ EDA Q IANEDAAQ IA ED  QG++ ED V
Sbjct: 128 ANEDAVHCIANEDAAQGIANEDAAHGIANEDAAQDIANEDAAQDIANEDAAQGISKEDAV 187

Query: 228 QGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANE 287
           QG+ANEDA QG+A E  VQGVA+ED VQG+ANEDA  GI         A ED  QG+ANE
Sbjct: 188 QGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGI---------AKEDPVQGVANE 238

Query: 288 DAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGI 347
           D  QG+A+EDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAA GIANEVA QGI
Sbjct: 239 DPVQGVANEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGI 298

Query: 348 ATEDVADGIANEDAAHGVA---------------------------KEVTAHGVANEDAV 380
           ATEDVADGIANEDAAHGVA                           KEVTAHGVANEDAV
Sbjct: 299 ATEDVADGIANEDAAHGVANEVAAQGVANEDAVEGVANEDAAQGVAKEVTAHGVANEDAV 358

Query: 381 QGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISK 440
           QGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEV          AQGIANEVA H I+ 
Sbjct: 359 QGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEV---------TAQGIANEVAIHSIAI 409

Query: 441 EDAVQGIA-----------NEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAA 489
           ED     A              +            +        ++       + +  + 
Sbjct: 410 EDTTPSRAWLTRSLPRASLPRMSPTASLRTPPMASLTRRPPRPSLSRMPPTASLTRTPSR 469

Query: 490 HGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANE 549
             +       ++ +      +        + T     G+ANE  V G+A++ A  G+ANE
Sbjct: 470 ASLTRSPPRASLTRTPPTASLTRSPPTASL-TRTPPRGVANEVEVQGIAHKDAIQGIANE 528

Query: 550 DAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGV 609
           DAAH IA   AAHGIANE A QGIA ED A GIANE AAHG++ E  V G+A EDA QG+
Sbjct: 529 DAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDTVQGIANEDAAQGI 588

Query: 610 ANEDAVHGVANEDAAQGIAKE 630
           A E+ V GVANED  QG+A E
Sbjct: 589 AKENPVQGVANEDPVQGVANE 609



 Score =  634 bits (1636), Expect = 0.0
 Identities = 358/607 (58%), Positives = 403/607 (66%), Gaps = 61/607 (10%)

Query: 522  EDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADG 581
            ED    IANEDAV+ +A E A + +ANEDA   IAK DAA GIANE A   IA ED A  
Sbjct: 13   EDTVHDIANEDAVYDIATEDAIYDIANEDAVQGIAKEDAAQGIANEEAVHDIANEDAAHV 72

Query: 582  IANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDA 641
            IANEDAA  +ANE AVH +A EDA QG+ NEDA H +ANEDAA G+A EV A GVANEDA
Sbjct: 73   IANEDAAQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVAAQGVANEDA 132

Query: 642  VQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIA 701
            V  + NEDA  G+ ANEDAA  IA  DAA  IANE AA  IANEDAAQGI+ EDA QGIA
Sbjct: 133  VHCIANEDAAQGI-ANEDAAHGIANEDAAQDIANEDAAQDIANEDAAQGISKEDAVQGIA 191

Query: 702  NEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQ 761
            NE AA GI+KED VQG+ANED  QG+A+EDAVQGIA ED V GVA E    GVANED VQ
Sbjct: 192  NEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGIAKEDPVQGVANEDPVQGVANEDAVQ 251

Query: 762  GVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVA---------NED 812
            G+ANED V GVA EV   G+A+EDA   IA  DAA GIANEVAA G+A         NED
Sbjct: 252  GIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANED 311

Query: 813  AAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVV 872
            AA GVANE AAQGVANEDAV GVANEDAAQGVAKEVTAHGV NEDAVQGVVNE+ALHGVV
Sbjct: 312  AAHGVANEVAAQGVANEDAVEGVANEDAAQGVAKEVTAHGVANEDAVQGVVNEDALHGVV 371

Query: 873  ANEDAAQAIAKPDAAHGIANE----GVANEVAAQGIATEDVADGIA-------------- 914
            ANEDAAQAIAKPDAAHGIANE    G+ANEVA   IA ED     A              
Sbjct: 372  ANEDAAQAIAKPDAAHGIANEVTAQGIANEVAIHSIAIEDTTPSRAWLTRSLPRASLPRM 431

Query: 915  -------KDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAA---- 963
                         +T+     ++++     S+T   +   +        +          
Sbjct: 432  SPTASLRTPPMASLTRRPPRPSLSRMPPTASLTRTPSRASLTRSPPRASLTRTPPTASLT 491

Query: 964  -------------QGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQG 1010
                         +GVANEV  QG+A++DA+ G+ANEDA  G+ANEV   GIA++DA QG
Sbjct: 492  RSPPTASLTRTPPRGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQG 551

Query: 1011 IANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDA 1070
            IANEDAA GIANEVAAHGI+ ED  QGIANEDAAQGIA         KE+ VQG+ANED 
Sbjct: 552  IANEDAAQGIANEVAAHGISKEDTVQGIANEDAAQGIA---------KENPVQGVANEDP 602

Query: 1071 AQGIANE 1077
             QG+ANE
Sbjct: 603  VQGVANE 609



 Score =  632 bits (1630), Expect = e-180
 Identities = 342/624 (54%), Positives = 404/624 (64%), Gaps = 47/624 (7%)

Query: 915  KDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQG 974
            +D  H I  E+A   IA +DA + I NEDA QG+A EDAA G+ANE+A   +ANE AA  
Sbjct: 13   EDTVHDIANEDAVYDIATEDAIYDIANEDAVQGIAKEDAAQGIANEEAVHDIANEDAAHV 72

Query: 975  VANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDA 1034
            +ANEDA   +ANEDAV  +ANE   QGI ++DA   IANEDAAHG+ANEVAA G+ANEDA
Sbjct: 73   IANEDAAQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVAAQGVANEDA 132

Query: 1035 AQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIAN 1094
               IANEDAAQGIANE AAHGI+ EDA Q IANEDAAQ IANEDAAQGI+ EDAVQGIAN
Sbjct: 133  VHCIANEDAAQGIANEDAAHGIANEDAAQDIANEDAAQDIANEDAAQGISKEDAVQGIAN 192

Query: 1095 EDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHG 1154
            EDA  G+AKE         DPVQGVANED VQGVANE  VQG+A ED VQG+ANED   G
Sbjct: 193  EDAAQGIAKE---------DPVQGVANEDPVQGVANEDAVQGIAKEDPVQGVANEDPVQG 243

Query: 1155 IANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDA 1214
            +ANE A  GIANEDA  G+A E AA G+A+EDA   IA  DA  G+A EVAA G+A ED 
Sbjct: 244  VANEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDV 303

Query: 1215 AHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIAN 1274
            A  IA  DAA G+ANEVAAQG+A ED  +G+ANEDAA GVA EV AHG++ EDAVQG+ N
Sbjct: 304  ADGIANEDAAHGVANEVAAQGVANEDAVEGVANEDAAQGVAKEVTAHGVANEDAVQGVVN 363

Query: 1275 EDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQG 1334
            EDA  G+        +ANEDAAQ IAK D   G+ANE   QG+ANEV +  +A ED    
Sbjct: 364  EDALHGV--------VANEDAAQAIAKPDAAHGIANEVTAQGIANEVAIHSIAIEDTTPS 415

Query: 1335 IA--------------------NEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKE 1374
             A                           +        ++       +    +   +++ 
Sbjct: 416  RAWLTRSLPRASLPRMSPTASLRTPPMASLTRRPPRPSLSRMPPTASLTRTPSRASLTRS 475

Query: 1375 DAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGI 1434
                 +        + +  P   +      +GVANEVEVQG+AH+DA+QGIANEDAAHGI
Sbjct: 476  PPRASLTRTPPTASLTRSPPTASLTRTPP-RGVANEVEVQGIAHKDAIQGIANEDAAHGI 534

Query: 1435 ANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAA 1494
            ANEVAAHGIANEDAAQGIANEDAA         QGIANE A HG++KE    G+ANEDAA
Sbjct: 535  ANEVAAHGIANEDAAQGIANEDAA---------QGIANEVAAHGISKEDTVQGIANEDAA 585

Query: 1495 HAIAKPDAARGIANEVATQGIATE 1518
              IAK +  +G+ANE   QG+A E
Sbjct: 586  QGIAKENPVQGVANEDPVQGVANE 609



 Score =  627 bits (1618), Expect = e-179
 Identities = 345/608 (56%), Positives = 405/608 (66%), Gaps = 38/608 (6%)

Query: 1636 EVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHG 1695
            E   H I+ EDAV  IA EDA   IANEDA QGIA EDA QGIANE+AVH +A E AAH 
Sbjct: 13   EDTVHDIANEDAVYDIATEDAIYDIANEDAVQGIAKEDAAQGIANEEAVHDIANEDAAHV 72

Query: 1696 VANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDA 1755
            +ANED  Q +ANEDAV  +ANE   QG+ +EDA   IANEDAAHG+ NEVAA G+ANEDA
Sbjct: 73   IANEDAAQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVAAQGVANEDA 132

Query: 1756 AQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIAT 1815
               IA+EDA QGIANEDA         AHG+ANEDAA  IA  DAA+ IANE AAQGI+ 
Sbjct: 133  VHCIANEDAAQGIANEDA---------AHGIANEDAAQDIANEDAAQDIANEDAAQGISK 183

Query: 1816 EDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQG 1875
            ED   GI NEDAA G+A E    G++ ED VQG+ANEDA QGIAKEDP+QGVANE  VQG
Sbjct: 184  EDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGIAKEDPVQGVANEDPVQG 243

Query: 1876 VAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDA 1935
            VA+EDAVQGIANEDA HG+A E AA G+ANEDAA  IA  DAA+GI+ E A QGIA +D 
Sbjct: 244  VANEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDV 303

Query: 1936 AQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIAN 1995
            A GIA EDA  G+ANE AAQG+ANE A  G+ANEDAAQG+A E  A G+A+EDAVQG+ N
Sbjct: 304  ADGIANEDAAHGVANEVAAQGVANEDAVEGVANEDAAQGVAKEVTAHGVANEDAVQGVVN 363

Query: 1996 EDAVHG-VANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQ 2054
            EDA+HG VANEDAA AIAKPDAA GIANEV AQGIA E     IA ED     A     +
Sbjct: 364  EDALHGVVANEDAAQAIAKPDAAHGIANEVTAQGIANEVAIHSIAIEDTTPSRA--WLTR 421

Query: 2055 AIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITK------- 2107
            ++ +           + T  +A          ++      ++ +  +   +T+       
Sbjct: 422  SLPRASLPRMSPTASLRTPPMASLTRRPPRPSLSRMPPTASLTRTPSRASLTRSPPRASL 481

Query: 2108 -------------------EDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQ 2148
                                   +GV NEV  QG+A++DA  G+ANE AAHG+ANE AA 
Sbjct: 482  TRTPPTASLTRSPPTASLTRTPPRGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAH 541

Query: 2149 GVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANED 2208
            G+ANE AAQG+ANEDA QG+ANEV   GI+ +D +QGIANEDAAQG+A E    GVANED
Sbjct: 542  GIANEDAAQGIANEDAAQGIANEVAAHGISKEDTVQGIANEDAAQGIAKENPVQGVANED 601

Query: 2209 AAQGVANE 2216
              QGVANE
Sbjct: 602  PVQGVANE 609



 Score =  619 bits (1595), Expect = e-176
 Identities = 347/614 (56%), Positives = 405/614 (65%), Gaps = 31/614 (5%)

Query: 1527 EDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHS 1586
            ED  H +ANE A   IA E A++ +A EDAVQG+ KE  A G+ANE+AV  + NEDA H 
Sbjct: 13   EDTVHDIANEDAVYDIATEDAIYDIANEDAVQGIAKEDAAQGIANEEAVHDIANEDAAH- 71

Query: 1587 VVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKED 1646
            V+ANEDAAQ+IA  DA H IANE A   I N+DAA  IAN+DAA G+ANEVAA G++ ED
Sbjct: 72   VIANEDAAQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVAAQGVANED 131

Query: 1647 AVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVA 1706
            AV  IANEDAAQGIANEDAA GIA+EDA Q IANEDA   +A E AA G++ ED VQG+A
Sbjct: 132  AVHCIANEDAAQGIANEDAAHGIANEDAAQDIANEDAAQDIANEDAAQGISKEDAVQGIA 191

Query: 1707 NEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQ 1766
            NEDA QG+A E  VQGVA+ED VQG+ANEDA  GI  E    G+ANED  QG+A+EDAVQ
Sbjct: 192  NEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGIAKEDPVQGVANEDPVQGVANEDAVQ 251

Query: 1767 GIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNED 1826
            GIANEDAVH VAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGI NED
Sbjct: 252  GIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANED 311

Query: 1827 AAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIA 1886
            AAHGVANEVAA G++ EDAV+G+ANEDAAQG+AK         EV   GVA+EDAVQG+ 
Sbjct: 312  AAHGVANEVAAQGVANEDAVEGVANEDAAQGVAK---------EVTAHGVANEDAVQGVV 362

Query: 1887 NEDAAHG-IANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAA--------- 1936
            NEDA HG +ANEDAAQ IA  DAA  IANE  AQGI+ E A+  IA +D           
Sbjct: 363  NEDALHGVVANEDAAQAIAKPDAAHGIANEVTAQGIANEVAIHSIAIEDTTPSRAWLTRS 422

Query: 1937 ---QGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGI 1993
                 + +      +     A  +        ++       +    +   +        +
Sbjct: 423  LPRASLPRMSPTASLRTPPMA-SLTRRPPRPSLSRMPPTASLTRTPSRASLTRSPPRASL 481

Query: 1994 ANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAA 2053
                    +       ++ +    RG+ANEV  QGIA +D   GIANEDAAHG+ANE AA
Sbjct: 482  TRTPPTASLTRSPPTASLTR-TPPRGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAA 540

Query: 2054 QAIAKPDAAHGIANEGIATEDVADGIA-EDAVQGITNEEAAQAIAKQDAAHGITKEDAAQ 2112
              IA  DAA GIAN     ED A GIA E A  GI+ E+  Q IA +DAA GI KE+  Q
Sbjct: 541  HGIANEDAAQGIAN-----EDAAQGIANEVAAHGISKEDTVQGIANEDAAQGIAKENPVQ 595

Query: 2113 GVTNEVAAQGVANE 2126
            GV NE   QGVANE
Sbjct: 596  GVANEDPVQGVANE 609



 Score =  610 bits (1573), Expect = e-174
 Identities = 344/615 (55%), Positives = 387/615 (62%), Gaps = 46/615 (7%)

Query: 1203 EVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHG 1262
            E   H +ANEDA + IA  DA   IANE A QGIA ED A GIANE+A H +ANE AAH 
Sbjct: 13   EDTVHDIANEDAVYDIATEDAIYDIANEDAVQGIAKEDAAQGIANEEAVHDIANEDAAHV 72

Query: 1263 ISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVE 1322
            I+ EDA Q IANEDA   IA EDA QGI NEDAA  IA ED   GVANE   QGVANE  
Sbjct: 73   IANEDAAQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVAAQGVANEDA 132

Query: 1323 VQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIAN 1382
            V  +A+EDA QGIANEDAAHGIANEDAAQ IANEDAAQDIANEDAAQGISKEDAVQGIAN
Sbjct: 133  VHCIANEDAAQGIANEDAAHGIANEDAAQDIANEDAAQDIANEDAAQGISKEDAVQGIAN 192

Query: 1383 EDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHG 1442
            EDAAQGIAKEDPVQGVANED VQGVANE  VQG+A ED VQG+ANED   G+ANE A  G
Sbjct: 193  EDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGIAKEDPVQGVANEDPVQGVANEDAVQG 252

Query: 1443 IANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDA 1502
            IANEDA  G+A E AA G+A+EDA   IA  DA  G+A EVAA G+A ED A  IA  DA
Sbjct: 253  IANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDA 312

Query: 1503 ARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVK 1562
            A G+ANEVA QG+A ED  +G+ANEDAA GVA EV A G+ANE AV GV  EDA+ GV  
Sbjct: 313  AHGVANEVAAQGVANEDAVEGVANEDAAQGVAKEVTAHGVANEDAVQGVVNEDALHGV-- 370

Query: 1563 EVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQ 1622
                  VANEDA Q +   DA H  +ANE  AQ         GIANEVA HSIA +D   
Sbjct: 371  ------VANEDAAQAIAKPDAAHG-IANEVTAQ---------GIANEVAIHSIAIEDTTP 414

Query: 1623 GIA--------------------NQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAN 1662
              A                           +        +S+      +    +   +  
Sbjct: 415  SRAWLTRSLPRASLPRMSPTASLRTPPMASLTRRPPRPSLSRMPPTASLTRTPSRASLTR 474

Query: 1663 EDAAQGIAHEDAVQGIANEDAV--------HGVAKEVAAHGVANEDPVQGVANEDAVQGV 1714
                  +        +               GVA EV   G+A++D +QG+ANEDA  G+
Sbjct: 475  SPPRASLTRTPPTASLTRSPPTASLTRTPPRGVANEVEVQGIAHKDAIQGIANEDAAHGI 534

Query: 1715 ANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAV 1774
            ANEV   G+A+EDA QGIANEDAA GI NEVAAHGI+ ED  QGIA+EDA QGIA E+ V
Sbjct: 535  ANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDTVQGIANEDAAQGIAKENPV 594

Query: 1775 HSVAKEVAAHGVANE 1789
              VA E    GVANE
Sbjct: 595  QGVANEDPVQGVANE 609



 Score =  607 bits (1565), Expect = e-173
 Identities = 339/617 (54%), Positives = 394/617 (63%), Gaps = 48/617 (7%)

Query: 1328 HEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQ 1387
            +ED V  IANEDA + IA EDA   IANEDA Q IA EDAAQGI+ E+AV  IANEDAA 
Sbjct: 12   YEDTVHDIANEDAVYDIATEDAIYDIANEDAVQGIAKEDAAQGIANEEAVHDIANEDAAH 71

Query: 1388 GIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANED 1447
             IA ED  Q +ANEDAV  +ANE   QG+ +EDA   IANEDAAHG+ANEVAA G+ANED
Sbjct: 72   VIANEDAAQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVAAQGVANED 131

Query: 1448 AAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIA 1507
            A   IANEDAAQGIA+EDA  GIANEDA   +A E AA  +ANEDAA  I+K DA +GIA
Sbjct: 132  AVHCIANEDAAQGIANEDAAHGIANEDAAQDIANEDAAQDIANEDAAQGISKEDAVQGIA 191

Query: 1508 NEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAH 1567
            NE A QGIA ED   G+ANED   GVANE A QGIA E  V GVA ED VQGV  E    
Sbjct: 192  NEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGIAKEDPVQGVANEDPVQGVANEDAVQ 251

Query: 1568 GVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQ 1627
            G+ANEDAV GV  E A H  VANEDAA AIAKPDAA GIANEVAA  IA +D A GIAN+
Sbjct: 252  GIANEDAVHGVAKEVAAHG-VANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANE 310

Query: 1628 DAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1687
            DAA G+ANEVAA G++ EDAV+G+ANEDAAQG+A E  A G+A+EDAVQG+ NEDA+HGV
Sbjct: 311  DAAHGVANEVAAQGVANEDAVEGVANEDAAQGVAKEVTAHGVANEDAVQGVVNEDALHGV 370

Query: 1688 AKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAA--------- 1738
                    VANED  Q +A  DA  G+ANEV  QG+A+E A+  IA ED           
Sbjct: 371  --------VANEDAAQAIAKPDAAHGIANEVTAQGIANEVAIHSIAIEDTTPSRAWLTRS 422

Query: 1739 --------------------HGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVA 1778
                                  +T       ++       +    +   +       S+ 
Sbjct: 423  LPRASLPRMSPTASLRTPPMASLTRRPPRPSLSRMPPTASLTRTPSRASLTRSPPRASLT 482

Query: 1779 KEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAH 1838
            +      +       ++ +    RG+ANEV  QGIA +D   GI NEDAAHG+ANEVAAH
Sbjct: 483  RTPPTASLTRSPPTASLTR-TPPRGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAH 541

Query: 1839 GISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANED 1898
            GI+ EDA QGIANEDAAQGI         ANEV   G++ ED VQGIANEDAA GIA E+
Sbjct: 542  GIANEDAAQGIANEDAAQGI---------ANEVAAHGISKEDTVQGIANEDAAQGIAKEN 592

Query: 1899 AAQGIANEDAAQDIANE 1915
              QG+ANED  Q +ANE
Sbjct: 593  PVQGVANEDPVQGVANE 609



 Score =  598 bits (1541), Expect = e-170
 Identities = 323/598 (54%), Positives = 382/598 (63%), Gaps = 24/598 (4%)

Query: 729  HEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQ 788
            +ED V  IANEDAV+ +A E A + +ANED VQG+A ED  QG+ANE  V  IA+EDA  
Sbjct: 12   YEDTVHDIANEDAVYDIATEDAIYDIANEDAVQGIAKEDAAQGIANEEAVHDIANEDAAH 71

Query: 789  GIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEV 848
             IANEDAA  IANE A H +ANEDA QG+ NEDAA  +ANEDA HGVANE AAQGVA E 
Sbjct: 72   VIANEDAAQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVAAQGVANED 131

Query: 849  TAHGVTNEDAVQGVVNEEALHGV--------VANEDAAQAIAKPDAAHGIANE----GVA 896
              H + NEDA QG+ NE+A HG+        +ANEDAAQ IA  DAA GI+ E    G+A
Sbjct: 132  AVHCIANEDAAQGIANEDAAHGIANEDAAQDIANEDAAQDIANEDAAQGISKEDAVQGIA 191

Query: 897  NEVAAQGIATEDVADGIA-KDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAH 955
            NE AAQGIA ED   G+A +D   G+  E+A Q IAK+D    + NED  QGVANEDA  
Sbjct: 192  NEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGIAKEDPVQGVANEDPVQGVANEDAVQ 251

Query: 956  GVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANED 1015
            G+ANEDA  GVA EVAA GVANEDA H +A  DA +G+ANEV  QGIA +D   GIANED
Sbjct: 252  GIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANED 311

Query: 1016 AAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG-I 1074
            AAHG+ANEVAA G+ANEDA +G+ANEDAAQG+A EV AHG++ EDAVQG+ NEDA  G +
Sbjct: 312  AAHGVANEVAAQGVANEDAVEGVANEDAAQGVAKEVTAHGVANEDAVQGVVNEDALHGVV 371

Query: 1075 ANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANED--PVQGVANEDAVQGVANEV 1132
            ANEDAAQ IA  DA  GIANE    G+A EVA H +A ED  P +        +     +
Sbjct: 372  ANEDAAQAIAKPDAAHGIANEVTAQGIANEVAIHSIAIEDTTPSRAWLTRSLPRASLPRM 431

Query: 1133 EVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIA 1192
                      +  +        ++       +    +   +        +        + 
Sbjct: 432  SPTASLRTPPMASLTRRPPRPSLSRMPPTASLTRTPSRASLTRSPPRASLTRTPPTASLT 491

Query: 1193 NEDAV--------HGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADG 1244
                          GVA EV   G+A++DA   IA  DAA GIANEVAA GIA ED A G
Sbjct: 492  RSPPTASLTRTPPRGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQG 551

Query: 1245 IANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKE 1302
            IANEDAA G+ANEVAAHGISKED VQGIANEDAAQGIAKE+ VQG+ANED  QG+A E
Sbjct: 552  IANEDAAQGIANEVAAHGISKEDTVQGIANEDAAQGIAKENPVQGVANEDPVQGVANE 609



 Score =  594 bits (1532), Expect = e-169
 Identities = 330/616 (53%), Positives = 387/616 (62%), Gaps = 28/616 (4%)

Query: 1004 HKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQ 1063
            ++D +  IANEDA + IA E A + IANEDA QGIA EDAAQGIANE A H I+ EDA  
Sbjct: 12   YEDTVHDIANEDAVYDIATEDAIYDIANEDAVQGIAKEDAAQGIANEEAVHDIANEDAAH 71

Query: 1064 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANED 1123
             IANEDAAQ IANEDA   IA+EDA QGI NEDA H +A E AAHGVANE   QGVANED
Sbjct: 72   VIANEDAAQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVAAQGVANED 131

Query: 1124 AVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIA 1183
            AV  +ANE   QG+A+EDA  GIANEDAA  IANE AA  IANEDAAQGI+ EDA QGIA
Sbjct: 132  AVHCIANEDAAQGIANEDAAHGIANEDAAQDIANEDAAQDIANEDAAQGISKEDAVQGIA 191

Query: 1184 HEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVAD 1243
            +EDA QGIA ED V GVA E    GVANEDA   IAK D  +G+ANE   QG+A ED   
Sbjct: 192  NEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGIAKEDPVQGVANEDPVQGVANEDAVQ 251

Query: 1244 GIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKED 1303
            GIANEDA HGVA EVAAH         G+ANEDAA  IAK DA +GIANE AAQGIA ED
Sbjct: 252  GIANEDAVHGVAKEVAAH---------GVANEDAAHAIAKPDAARGIANEVAAQGIATED 302

Query: 1304 PVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIA 1363
               G+ANED   GVANEV  QGVA+EDAV+G+ANEDAA G+A E  A G+ANEDA Q + 
Sbjct: 303  VADGIANEDAAHGVANEVAAQGVANEDAVEGVANEDAAQGVAKEVTAHGVANEDAVQGVV 362

Query: 1364 NEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQ 1423
            NEDA  G+        +ANEDAAQ IAK D   G+ANE   QG+ANEV +  +A ED   
Sbjct: 363  NEDALHGV--------VANEDAAQAIAKPDAAHGIANEVTAQGIANEVAIHSIAIEDTTP 414

Query: 1424 GIA--NEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAK 1481
              A             ++            +        ++       +    +   + +
Sbjct: 415  SRAWLTRSLPRASLPRMSPTASLRTPPMASLTRRPPRPSLSRMPPTASLTRTPSRASLTR 474

Query: 1482 EVAAHGVANEDAAHAIAK--PDAA------RGIANEVATQGIATEDVADGIANEDAAHGV 1533
                  +       ++ +  P A+      RG+ANEV  QGIA +D   GIANEDAAHG+
Sbjct: 475  SPPRASLTRTPPTASLTRSPPTASLTRTPPRGVANEVEVQGIAHKDAIQGIANEDAAHGI 534

Query: 1534 ANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDA 1593
            ANEVAA GIANE A  G+A EDA QG+  EV AHG++ ED VQG+ NEDA    +A E+ 
Sbjct: 535  ANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDTVQGIANEDAAQG-IAKENP 593

Query: 1594 AQAIAKPDAAHGIANE 1609
             Q +A  D   G+ANE
Sbjct: 594  VQGVANEDPVQGVANE 609



 Score =  592 bits (1525), Expect = e-168
 Identities = 330/592 (55%), Positives = 382/592 (64%), Gaps = 50/592 (8%)

Query: 895  VANEVAAQGIATEDVADGIA-KDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDA 953
            +ANE A   IATED    IA +DA  GI KE+AAQ IA ++A H I NEDAA  +ANEDA
Sbjct: 19   IANEDAVYDIATEDAIYDIANEDAVQGIAKEDAAQGIANEEAVHDIANEDAAHVIANEDA 78

Query: 954  AHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIAN 1013
            A  +ANEDA   +ANE A QG+ NEDA H +ANEDA  GVANEV  QG+A++DA+  IAN
Sbjct: 79   AQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVAAQGVANEDAVHCIAN 138

Query: 1014 EDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG 1073
            EDAA GIANE AAHGIANEDAAQ IANEDAAQ IANE AA GISKEDAVQGIANEDAAQG
Sbjct: 139  EDAAQGIANEDAAHGIANEDAAQDIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQG 198

Query: 1074 IANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVE 1133
            IA ED  QG+A+ED VQG+ANEDAV G+AKE    GVANEDPVQGVANEDAVQG+ANE  
Sbjct: 199  IAKEDPVQGVANEDPVQGVANEDAVQGIAKEDPVQGVANEDPVQGVANEDAVQGIANEDA 258

Query: 1134 VQGVAHEDAVQGIANEDAAH---------GIANEVAAHGIANEDAAQGIANEDAAQGIAH 1184
            V GVA E A  G+ANEDAAH         GIANEVAA GIA ED A GIANEDAA G+A+
Sbjct: 259  VHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVAN 318

Query: 1185 EDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGI-ATEDVAD 1243
            E A QG+ANEDAV GVA E AA GVA E  AH +A  DA +G+ NE A  G+ A ED A 
Sbjct: 319  EVAAQGVANEDAVEGVANEDAAQGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQ 378

Query: 1244 GIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQG----------------------- 1280
             IA  DAAHG+ANEV A GI+ E A+  IA ED                           
Sbjct: 379  AIAKPDAAHGIANEVTAQGIANEVAIHSIAIEDTTPSRAWLTRSLPRASLPRMSPTASLR 438

Query: 1281 ---------------IAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQG 1325
                           +++      +    +   + +  P   +    P   +        
Sbjct: 439  TPPMASLTRRPPRPSLSRMPPTASLTRTPSRASLTRSPPRASLTRTPPTASLTRSPPTAS 498

Query: 1326 VAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDA 1385
            +      +G+ANE    GIA++DA QGIANEDAA  IANE AA GI+ EDA QGIANEDA
Sbjct: 499  LTRTPP-RGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDA 557

Query: 1386 AQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANE 1437
            AQGIA E    G++ ED VQG+ANE   QG+A E+ VQG+ANED   G+ANE
Sbjct: 558  AQGIANEVAAHGISKEDTVQGIANEDAAQGIAKENPVQGVANEDPVQGVANE 609



 Score =  565 bits (1455), Expect = e-160
 Identities = 335/607 (55%), Positives = 377/607 (62%), Gaps = 90/607 (14%)

Query: 1744 EVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARG 1803
            E   H IANEDA   IA EDA+  IANEDAV  +AKE AA G+ANE+A H IA  DAA  
Sbjct: 13   EDTVHDIANEDAVYDIATEDAIYDIANEDAVQGIAKEDAAQGIANEEAVHDIANEDAAHV 72

Query: 1804 IANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDP 1863
            IANE AAQ IA ED    I NEDA  G+ NE AAH I+ EDA  G+ANE AAQG+A ED 
Sbjct: 73   IANEDAAQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVAAQGVANEDA 132

Query: 1864 IQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISK 1923
            +  +ANE         DA QGIANEDAAHGIANEDAAQ IANEDAAQDIANEDAAQGISK
Sbjct: 133  VHCIANE---------DAAQGIANEDAAHGIANEDAAQDIANEDAAQDIANEDAAQGISK 183

Query: 1924 EDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQG 1983
            EDAVQGIAN+DAAQGIAKED VQG+ANED  QG+ANE A  GIA ED  QG+ANED  QG
Sbjct: 184  EDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGIAKEDPVQGVANEDPVQG 243

Query: 1984 IAHEDAVQGIANEDAVHGVA---------NEDAAHAIAKPDAARGIANEVAAQGIATEDV 2034
            +A+EDAVQGIANEDAVHGVA         NEDAAHAIAKPDAARGIANEVAAQGIATEDV
Sbjct: 244  VANEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDV 303

Query: 2035 ADGIANEDA------------------------------------AHGVANEDA------ 2052
            ADGIANEDA                                    AHGVANEDA      
Sbjct: 304  ADGIANEDAAHGVANEVAAQGVANEDAVEGVANEDAAQGVAKEVTAHGVANEDAVQGVVN 363

Query: 2053 -------------AQAIAKPDAAHGIANE----GIATEDVADGIA-EDAVQG---ITNEE 2091
                         AQAIAKPDAAHGIANE    GIA E     IA ED       +T   
Sbjct: 364  EDALHGVVANEDAAQAIAKPDAAHGIANEVTAQGIANEVAIHSIAIEDTTPSRAWLTRSL 423

Query: 2092 AAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVA 2151
               ++ +      +     A  +T       ++       +    +   +        + 
Sbjct: 424  PRASLPRMSPTASLRTPPMAS-LTRRPPRPSLSRMPPTASLTRTPSRASLTRSPPRASLT 482

Query: 2152 NEVAAQGVANEDAV--------QGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHG 2203
                   +              +GVANEVEVQGIAHKDAIQGIANEDAA G+ANEVAAHG
Sbjct: 483  RTPPTASLTRSPPTASLTRTPPRGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHG 542

Query: 2204 VANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDA 2263
            +ANEDAAQG+ANE AAQG+ANE AA G++ E  V G+ANEDAA+ +AKE+  QG+ANED 
Sbjct: 543  IANEDAAQGIANEDAAQGIANEVAAHGISKEDTVQGIANEDAAQGIAKENPVQGVANEDP 602

Query: 2264 AHGIANE 2270
              G+ANE
Sbjct: 603  VQGVANE 609



 Score =  528 bits (1360), Expect = e-149
 Identities = 287/529 (54%), Positives = 340/529 (64%), Gaps = 19/529 (3%)

Query: 46  ESTPYEDTVHDIANEDA-------DAAHGITNEDAVQGVANEVAAQGVANEDAAH----- 93
           +S   ED VHDIANEDA       DAAH I NEDA  GVANEVAAQGVANEDA H     
Sbjct: 80  QSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVAAQGVANEDAVHCIANE 139

Query: 94  ----GVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEDAVQGVANEDAVQGI 149
               G+ANE AAHG+ANEDAAQ +ANE AAQ +ANEDA QG++ EDAVQG+ANEDA QGI
Sbjct: 140 DAAQGIANEDAAHGIANEDAAQDIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGI 199

Query: 150 ANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQGISKEDAVQGIANEDAA 209
           A ED   G+ANED  QG+ANEDA Q IAKED  Q +ANED  QG++ EDAVQGIANEDA 
Sbjct: 200 AKEDPVQGVANEDPVQGVANEDAVQGIAKEDPVQGVANEDPVQGVANEDAVQGIANEDAV 259

Query: 210 QGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNE 269
            G+AKE    GVANED    +A  DA +G+ANEV  QG+A ED   GIANEDAAHG+ NE
Sbjct: 260 HGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANE 319

Query: 270 VAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHG-VANEDAAHA 328
           VAA G+ANEDA +G+ANEDAAQG+A E    G+ANEDAV GV  E A HG VANEDAA A
Sbjct: 320 VAAQGVANEDAVEGVANEDAAQGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQA 379

Query: 329 IAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKEVTAHGVANEDAVQGVVN-ED 387
           IAKPDAAHGIANEV  QGIA E     IA ED     A    +   A+   +    +   
Sbjct: 380 IAKPDAAHGIANEVTAQGIANEVAIHSIAIEDTTPSRAWLTRSLPRASLPRMSPTASLRT 439

Query: 388 ALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGI 447
                +       ++++      +    +   +        +        +++      +
Sbjct: 440 PPMASLTRRPPRPSLSRMPPTASLTRTPSRASLTRSPPRASLTRTPPTASLTRSPPTASL 499

Query: 448 ANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAA 507
                 +G+A+E   QGIAH+DA+QGIANEDA HG+A EVAAHG+AN+DAA  IA  DAA
Sbjct: 500 -TRTPPRGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAA 558

Query: 508 RGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIA 556
           +GIANEVAA GI+ ED   GIANEDA  G+A E    GVANED    +A
Sbjct: 559 QGIANEVAAHGISKEDTVQGIANEDAAQGIAKENPVQGVANEDPVQGVA 607



 Score =  525 bits (1352), Expect = e-148
 Identities = 309/538 (57%), Positives = 347/538 (64%), Gaps = 45/538 (8%)

Query: 1870 EVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQG 1929
            E  V  +A+EDAV  IA EDA + IANEDA QGIA EDAAQ IANE+A   I+ EDA   
Sbjct: 13   EDTVHDIANEDAVYDIATEDAIYDIANEDAVQGIAKEDAAQGIANEEAVHDIANEDAAHV 72

Query: 1930 IANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDA 1989
            IAN+DAAQ IA EDAV  IANEDA QGI NE AAH IANEDAA G+ANE AAQG+A+EDA
Sbjct: 73   IANEDAAQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVAAQGVANEDA 132

Query: 1990 VQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVAN 2049
            V  IANEDA  G+ANEDAAH IA  DAA+ IANE AAQ IA ED A GI+ EDA  G+AN
Sbjct: 133  VHCIANEDAAQGIANEDAAHGIANEDAAQDIANEDAAQDIANEDAAQGISKEDAVQGIAN 192

Query: 2050 EDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKED 2109
            EDAAQ IAK D   G+ANE             D VQG+ NE+A Q IAK+D   G+  ED
Sbjct: 193  EDAAQGIAKEDPVQGVANE-------------DPVQGVANEDAVQGIAKEDPVQGVANED 239

Query: 2110 AAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVA 2169
              QGV NE A QG+ANEDA HGVA EVAAHGVANEDAA  +A   AA+G+ANE A QG+A
Sbjct: 240  PVQGVANEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIA 299

Query: 2170 NEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQ 2229
             E    GIA++DA  G+ANE AAQGVANE A  GVANEDAAQGVA EV A GVANEDA Q
Sbjct: 300  TEDVADGIANEDAAHGVANEVAAQGVANEDAVEGVANEDAAQGVAKEVTAHGVANEDAVQ 359

Query: 2230 GVANEVAVHGV-ANEDAARHMAKEDAAQGIANEDAAHGIANEDAVHGIANEDAVYDIA-- 2286
            GV NE A+HGV ANEDAA+ +AK DAA GIANE  A GIANE A+H IA ED     A  
Sbjct: 360  GVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVTAQGIANEVAIHSIAIEDTTPSRAWL 419

Query: 2287 ------------------NDTVQGTLTRTLYRTSLMRTPYKASVMRTLYTTSLTRTPYKP 2328
                                    +LTR   R SL R P  AS+ RT    SLTR+P + 
Sbjct: 420  TRSLPRASLPRMSPTASLRTPPMASLTRRPPRPSLSRMPPTASLTRTPSRASLTRSPPRA 479

Query: 2329 SLTRTLYTTSLMRAPYKTS----PMRALYTTLLMIPTRH-------ANADTVHDIANE 2375
            SLTRT  T SL R+P   S    P R +   + +    H       AN D  H IANE
Sbjct: 480  SLTRTPPTASLTRSPPTASLTRTPPRGVANEVEVQGIAHKDAIQGIANEDAAHGIANE 537


>gi|239746643 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 454

 Score =  367 bits (941), Expect = e-100
 Identities = 204/341 (59%), Positives = 228/341 (66%), Gaps = 53/341 (15%)

Query: 2081 EDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHG 2140
            ED V  ITNE         DA+H IT EDA  G+ NE A +G ANEDAA G+ANE AAHG
Sbjct: 124  EDTVHNITNE---------DASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHG 174

Query: 2141 VANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVA 2200
            +A+EDAAQG+ANEVAAQG+ANEDA QG+ANE  VQGIA++DA  GIANEDAA G+ANE A
Sbjct: 175  IASEDAAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDA 234

Query: 2201 AHGVANEDAAQGVANEVAAQGVANEDAAQGVANE--------------VAVHGVANEDAA 2246
             HG+ANED+   +ANE A   +AN D  QG                  + +  +      
Sbjct: 235  VHGIANEDSVYDIANEDAIYDIAN-DTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLT 293

Query: 2247 RHMAKEDAAQGI-----------------------------ANEDAAHGIANEDAVHGIA 2277
            R + K    + +                             AN D  H IANED+V+ IA
Sbjct: 294  RTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIA 353

Query: 2278 NEDAVYDIANDTVQGTLTRTLYRTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTT 2337
            NE AVYDIANDTVQGTLTRTLY TSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTT
Sbjct: 354  NEGAVYDIANDTVQGTLTRTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTT 413

Query: 2338 SLMRAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDTV 2378
            SLM APYKTSPMRALYTTLLMIPTRHAN D VHDIANEDTV
Sbjct: 414  SLMTAPYKTSPMRALYTTLLMIPTRHANVDAVHDIANEDTV 454



 Score =  353 bits (906), Expect = 1e-96
 Identities = 181/236 (76%), Positives = 199/236 (84%), Gaps = 9/236 (3%)

Query: 2143 NEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAH 2202
            +ED    + NE A+  + NEDAV G+ANE          A +G ANEDAAQG+ANE AAH
Sbjct: 123  HEDTVHNITNEDASHDITNEDAVHGIANEA---------ADKGNANEDAAQGIANEDAAH 173

Query: 2203 GVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANED 2262
            G+A+EDAAQG+ANEVAAQG+ANEDAAQG+ANE AV G+ANEDAA  +A EDAA GIANED
Sbjct: 174  GIASEDAAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANED 233

Query: 2263 AAHGIANEDAVHGIANEDAVYDIANDTVQGTLTRTLYRTSLMRTPYKASVMRTLYTTSLT 2322
            A HGIANED+V+ IANEDA+YDIANDTVQGTL RTLY TSLMRTPYKA VMRTLY TSLT
Sbjct: 234  AVHGIANEDSVYDIANEDAIYDIANDTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLT 293

Query: 2323 RTPYKPSLTRTLYTTSLMRAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDTV 2378
            RT YKPSLTRTLYTTSLM APYKTSPMRALYTTLLMIPTRHANADTVHDIANED+V
Sbjct: 294  RTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSV 349



 Score =  285 bits (730), Expect = 3e-76
 Identities = 162/284 (57%), Positives = 187/284 (65%), Gaps = 47/284 (16%)

Query: 16  SSEESLVHKDRGDGERPVNVRVVQVAPLRHESTPYEDTVHDIANEDADAAHGITNEDAVQ 75
           +SEESLVHKDRGDGERPVNVRVVQVAPLRHESTP+EDTVH+I NEDA  +H ITNEDAV 
Sbjct: 89  ASEESLVHKDRGDGERPVNVRVVQVAPLRHESTPHEDTVHNITNEDA--SHDITNEDAVH 146

Query: 76  GVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANED 135
           G+ANE A +G ANEDAA G+ANE AAHG+A+EDAAQG+ANEVAAQG+ANEDA QG+ANED
Sbjct: 147 GIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQGIANEDAAQGIANED 206

Query: 136 AVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQG-- 193
           AVQG+ANEDA  GIANEDAAHGIANEDA  GIANED+  DIA EDA  DIAN D  QG  
Sbjct: 207 AVQGIANEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIAN-DTVQGTL 265

Query: 194 ------------------------------ISKEDAVQGIANEDAAQGIAKEDPVQGV-- 221
                                         + K    + +          K  P++ +  
Sbjct: 266 KRTLYTTSLMRTPYKALVMRTLYMTSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRALYT 325

Query: 222 ---------ANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQG 256
                    AN D V  +ANED+V  +ANE  V  +A+ D VQG
Sbjct: 326 TLLMIPTRHANADTVHDIANEDSVYHIANEGAVYDIAN-DTVQG 368



 Score =  201 bits (510), Expect = 9e-51
 Identities = 126/263 (47%), Positives = 147/263 (55%), Gaps = 36/263 (13%)

Query: 1324 QGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANE 1383
            +   HED V  I NEDA+H I NEDA  GIANE A +  ANEDAAQGI+ EDA  GIA+E
Sbjct: 119  ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASE 178

Query: 1384 DAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGI 1443
            DAAQGIA E   QG+ANEDA QG+ANE         DAVQGIANEDAAHGIANE AAHGI
Sbjct: 179  DAAQGIANEVAAQGIANEDAAQGIANE---------DAVQGIANEDAAHGIANEDAAHGI 229

Query: 1444 ANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE--------------VAAHGVA 1489
            ANEDA  GIANED+   IA+EDA+  IAN D V G  K               +    + 
Sbjct: 230  ANEDAVHGIANEDSVYDIANEDAIYDIAN-DTVQGTLKRTLYTTSLMRTPYKALVMRTLY 288

Query: 1490 NEDAAHAIAKPDAARGI-ANEVATQGIATED----------VADGIANEDAAHGVANEVA 1538
                   + KP   R +    + T    T            +    AN D  H +ANE +
Sbjct: 289  MTSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDS 348

Query: 1539 AQGIANEVAVHGVAIEDAVQGVV 1561
               IANE AV+ +A  D VQG +
Sbjct: 349  VYHIANEGAVYDIA-NDTVQGTL 370



 Score =  196 bits (497), Expect = 3e-49
 Identities = 100/142 (70%), Positives = 114/142 (80%), Gaps = 1/142 (0%)

Query: 1004 HKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQ 1063
            H+D +  I NEDA+H I NE A HGIANE A +G ANEDAAQGIANE AAHGI+ EDA Q
Sbjct: 123  HEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQ 182

Query: 1064 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANED 1123
            GIANE AAQGIANEDAAQGIA+EDAVQGIANEDA HG+A E AAHG+ANED V G+ANED
Sbjct: 183  GIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGIANED 242

Query: 1124 AVQGVANEVEVQGVAHEDAVQG 1145
            +V  +ANE  +  +A+ D VQG
Sbjct: 243  SVYDIANEDAIYDIAN-DTVQG 263



 Score =  195 bits (495), Expect = 5e-49
 Identities = 115/247 (46%), Positives = 144/247 (58%), Gaps = 9/247 (3%)

Query: 933  QDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQG 992
            +D  H+ITNEDA+  + NEDA HG+ANE A +G ANE AAQG+ANEDA HG+A+EDA QG
Sbjct: 124  EDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQG 183

Query: 993  VANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVA 1052
            +ANEV  QGIA++DA QGIANEDA  GIANE AAHGIANEDAA GIANEDA  GIANE +
Sbjct: 184  IANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGIANEDS 243

Query: 1053 AHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANE-----DAVHGVAKEVAA 1107
             + I+ EDA+  IAN D  QG                + +             + K    
Sbjct: 244  VYDIANEDAIYDIAN-DTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLTRTLYKPSLT 302

Query: 1108 HGVANEDPVQGVANEDAVQGVANEVEVQGVAH--EDAVQGIANEDAAHGIANEVAAHGIA 1165
              +     +        ++ +   + +    H   D V  IANED+ + IANE A + IA
Sbjct: 303  RTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIANEGAVYDIA 362

Query: 1166 NEDAAQG 1172
            N D  QG
Sbjct: 363  N-DTVQG 368



 Score =  193 bits (491), Expect = 1e-48
 Identities = 123/268 (45%), Positives = 142/268 (52%), Gaps = 50/268 (18%)

Query: 1135 QGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANE 1194
            +   HED V  I NEDA+H I NE A HGIANE A +G ANEDAAQGIA+EDA  GIA+E
Sbjct: 119  ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASE 178

Query: 1195 DAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGV 1254
            DA  G+A EVAA G+ANEDAA         +GIANE A QGIA ED A GIANEDAAHG+
Sbjct: 179  DAAQGIANEVAAQGIANEDAA---------QGIANEDAVQGIANEDAAHGIANEDAAHGI 229

Query: 1255 ANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVA----- 1309
            ANE A HGI+ ED+V  IANEDA   IA  D VQG              P + +      
Sbjct: 230  ANEDAVHGIANEDSVYDIANEDAIYDIA-NDTVQGTLKRTLYTTSLMRTPYKALVMRTLY 288

Query: 1310 ---------------------------NEDPIQGVANEVEVQGVAHEDAVQGIANEDAAH 1342
                                          P++ +   + +    H       AN D  H
Sbjct: 289  MTSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRH-------ANADTVH 341

Query: 1343 GIANEDAAQGIANEDAAQDIANEDAAQG 1370
             IANED+   IANE A  DIAN D  QG
Sbjct: 342  DIANEDSVYHIANEGAVYDIAN-DTVQG 368



 Score =  192 bits (487), Expect = 4e-48
 Identities = 115/248 (46%), Positives = 138/248 (55%), Gaps = 42/248 (16%)

Query: 1865 QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKE 1924
            +   +E  V  + +EDA   I NEDA HGIANE A +G ANEDAAQ IANEDAA GI+ E
Sbjct: 119  ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASE 178

Query: 1925 DAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGI 1984
            DA QGIAN+ AAQGIA EDA QGIANEDA QGIANE AAHGIANEDAA GIANEDA  GI
Sbjct: 179  DAAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGI 238

Query: 1985 AHEDAVQGIANEDAVHGVANE-------------------------------DAAHAIAK 2013
            A+ED+V  IANEDA++ +AN+                                    + K
Sbjct: 239  ANEDSVYDIANEDAIYDIANDTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLTRTLYK 298

Query: 2014 PDAARGI-----------ANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAA 2062
            P   R +            + + A       +    AN D  H +ANED+   IA   A 
Sbjct: 299  PSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIANEGAV 358

Query: 2063 HGIANEGI 2070
            + IAN+ +
Sbjct: 359  YDIANDTV 366



 Score =  191 bits (486), Expect = 6e-48
 Identities = 120/257 (46%), Positives = 145/257 (56%), Gaps = 27/257 (10%)

Query: 1040 NEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVH 1099
            +ED    I NE A+H I+ EDAV GIANE A +G ANEDAAQGIA+EDA  GIA+EDA  
Sbjct: 123  HEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQ 182

Query: 1100 GVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEV 1159
            G+A EVAA G+ANED  QG+ANEDAVQG+AN         EDA  GIANEDAAHGIANE 
Sbjct: 183  GIANEVAAQGIANEDAAQGIANEDAVQGIAN---------EDAAHGIANEDAAHGIANED 233

Query: 1160 AAHGIANEDAAQGIANEDAAQGIAHEDAVQG-----IANEDAVHGVAKEVAAHGVANEDA 1214
            A HGIANED+   IANEDA   IA+ D VQG     +     +    K +    +     
Sbjct: 234  AVHGIANEDSVYDIANEDAIYDIAN-DTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSL 292

Query: 1215 AHAIAKPDAARGI-----------ANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGI 1263
               + KP   R +            + + A       +    AN D  H +ANE + + I
Sbjct: 293  TRTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHI 352

Query: 1264 SKEDAVQGIANEDAAQG 1280
            + E AV  IAN D  QG
Sbjct: 353  ANEGAVYDIAN-DTVQG 368



 Score =  191 bits (484), Expect = 1e-47
 Identities = 116/253 (45%), Positives = 140/253 (55%), Gaps = 7/253 (2%)

Query: 1874 QGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQ 1933
            +   HED V  I NEDA+H I NEDA  GIANE A +  ANEDAAQGI+ EDA  GIA++
Sbjct: 119  ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASE 178

Query: 1934 DAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGI 1993
            DAAQGIA E A QGIANEDAAQGIANE A  GIANEDAA GIANEDAA GIA+EDAV GI
Sbjct: 179  DAAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGI 238

Query: 1994 ANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAA 2053
            ANED+V+ +ANEDA + IA  D  +G         + T  +            +      
Sbjct: 239  ANEDSVYDIANEDAIYDIAN-DTVQGTLKRT----LYTTSLMRTPYKALVMRTLYMTSLT 293

Query: 2054 QAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQG 2113
            + + KP     +    + T              +       A A  D  H I  ED+   
Sbjct: 294  RTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANA--DTVHDIANEDSVYH 351

Query: 2114 VTNEVAAQGVANE 2126
            + NE A   +AN+
Sbjct: 352  IANEGAVYDIAND 364



 Score =  188 bits (477), Expect = 6e-47
 Identities = 115/273 (42%), Positives = 143/273 (52%), Gaps = 27/273 (9%)

Query: 693 NEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAH 752
           +ED    I NE A+H I+ EDAV GIANE A +G A+EDA QGIANEDA HG+A E AA 
Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQ 182

Query: 753 GVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANED 812
           G+ANE   QG+ANED  QG+ANE         DAVQGIANEDAAHGIANE AAHG+ANED
Sbjct: 183 GIANEVAAQGIANEDAAQGIANE---------DAVQGIANEDAAHGIANEDAAHGIANED 233

Query: 813 AAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVV 872
           A  G+ANED+   +ANEDA++ +AN D  QG  K             + +V        +
Sbjct: 234 AVHGIANEDSVYDIANEDAIYDIAN-DTVQGTLKRTLYTTSLMRTPYKALVMR-----TL 287

Query: 873 ANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAK 932
                 + + KP     +    +                 +     H           A 
Sbjct: 288 YMTSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRH-----------AN 336

Query: 933 QDAAHSITNEDAAQGVANEDAAHGVANEDAAQG 965
            D  H I NED+   +ANE A + +AN D  QG
Sbjct: 337 ADTVHDIANEDSVYHIANEGAVYDIAN-DTVQG 368



 Score =  186 bits (471), Expect = 3e-46
 Identities = 117/250 (46%), Positives = 143/250 (57%), Gaps = 12/250 (4%)

Query: 385 NEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAV 444
           +ED +H +  NEDA+  I   DA HGIANE A  G ANEDAAQGIANE AAHGI+ EDA 
Sbjct: 123 HEDTVHNIT-NEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASEDAA 181

Query: 445 QGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKP 504
           QGIANE AAQGIA+EDAAQGIA+EDAVQGIANEDA HG+A E AAHG+AN+DA H IA  
Sbjct: 182 QGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGIANE 241

Query: 505 DAARGIANEVAAQGIATEDVADGIA----NEDAVHGVANEVAAHGVANEDAAHAIAKPDA 560
           D+   IANE A   IA + V   +         +      +    +        + KP  
Sbjct: 242 DSVYDIANEDAIYDIANDTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLTRTLYKPSL 301

Query: 561 AHGI-ANEVATQGIATEDVA---DGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVH 616
              +    + T    T  +      +      H  AN   VH +A ED+V  +ANE AV+
Sbjct: 302 TRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRH--ANADTVHDIANEDSVYHIANEGAVY 359

Query: 617 GVANEDAAQG 626
            +AN D  QG
Sbjct: 360 DIAN-DTVQG 368



 Score =  186 bits (471), Expect = 3e-46
 Identities = 114/247 (46%), Positives = 136/247 (55%), Gaps = 27/247 (10%)

Query: 1239 EDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQG 1298
            ED    I NEDA+H + NE A HGI+ E A +G ANEDAAQGIA EDA  GIA+EDAAQG
Sbjct: 124  EDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQG 183

Query: 1299 IAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDA 1358
            IA E   QG+ANED  QG+ANE  VQG+A+EDA  GIANEDAAHGIANEDA  GIANED+
Sbjct: 184  IANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGIANEDS 243

Query: 1359 AQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVA-------------NEDAVQ 1405
              DIANEDA   I+  D VQG              P + +               + ++ 
Sbjct: 244  VYDIANEDAIYDIA-NDTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLTRTLYKPSLT 302

Query: 1406 GVANEVEVQGVAHEDAVQGI------------ANEDAAHGIANEVAAHGIANEDAAQGIA 1453
                   +    ++ +                AN D  H IANE + + IANE A   IA
Sbjct: 303  RTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIANEGAVYDIA 362

Query: 1454 NEDAAQG 1460
            N D  QG
Sbjct: 363  N-DTVQG 368



 Score =  185 bits (469), Expect = 5e-46
 Identities = 103/179 (57%), Positives = 125/179 (69%), Gaps = 1/179 (0%)

Query: 940  TNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEV 999
            T E + + + ++D   G    +        +  +   +ED VH + NEDA   + NE  V
Sbjct: 86   TLEASEESLVHKDRGDGERPVNVRVVQVAPLRHESTPHEDTVHNITNEDASHDITNEDAV 145

Query: 1000 QGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKE 1059
             GIA++ A +G ANEDAA GIANE AAHGIA+EDAAQGIANE AAQGIANE AA GI+ E
Sbjct: 146  HGIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQGIANEDAAQGIANE 205

Query: 1060 DAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQG 1118
            DAVQGIANEDAA GIANEDAA GIA+EDAV GIANED+V+ +A E A + +AN D VQG
Sbjct: 206  DAVQGIANEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIAN-DTVQG 263



 Score =  185 bits (469), Expect = 5e-46
 Identities = 96/147 (65%), Positives = 111/147 (75%), Gaps = 1/147 (0%)

Query: 1585 HSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISK 1644
            H    +ED    I   DA+H I NE A H IAN+ A +G AN+DAAQGIANE AAHGI+ 
Sbjct: 118  HESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIAS 177

Query: 1645 EDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQG 1704
            EDA QGIANE AAQGIANEDAAQGIA+EDAVQGIANEDA HG+A E AAHG+ANED V G
Sbjct: 178  EDAAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHG 237

Query: 1705 VANEDAVQGVANEVEVQGVAHEDAVQG 1731
            +ANED+V  +ANE  +  +A+ D VQG
Sbjct: 238  IANEDSVYDIANEDAIYDIAN-DTVQG 263



 Score =  184 bits (468), Expect = 7e-46
 Identities = 115/282 (40%), Positives = 146/282 (51%), Gaps = 34/282 (12%)

Query: 1609 EVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQG 1668
            E +  S+ +KD   G    +        +       ED V  I NEDA+  I NEDA  G
Sbjct: 88   EASEESLVHKDRGDGERPVNVRVVQVAPLRHESTPHEDTVHNITNEDASHDITNEDAVHG 147

Query: 1669 IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDA 1728
            IA+E A +G ANEDA  G+A E AAHG+A+ED  QG+ANE A QG+ANE   QG+A+EDA
Sbjct: 148  IANEAADKGNANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQGIANEDAAQGIANEDA 207

Query: 1729 VQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVA---------- 1778
            VQGIANEDAAHGI NE AAHGIANEDA  GIA+ED+V  IANEDA++ +A          
Sbjct: 208  VQGIANEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIANDTVQGTLKR 267

Query: 1779 ------------KEVAAHGVANEDAAHAIAKPDAARGI-----------ANEVAAQGIAT 1815
                        K +    +        + KP   R +            + + A     
Sbjct: 268  TLYTTSLMRTPYKALVMRTLYMTSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTL 327

Query: 1816 EDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQG 1857
              +     N D  H +ANE + + I+ E AV  IAN D  QG
Sbjct: 328  LMIPTRHANADTVHDIANEDSVYHIANEGAVYDIAN-DTVQG 368



 Score =  184 bits (468), Expect = 7e-46
 Identities = 109/243 (44%), Positives = 135/243 (55%), Gaps = 26/243 (10%)

Query: 169 NEDAAQDIAKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQ 228
           +ED   +I  EDA+ DI NEDA  GI+ E A +G ANEDAAQGIA ED   G+A+ED  Q
Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQ 182

Query: 229 GVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANED 288
           G+ANE A QG+ANE   QG+A+EDAVQGIANEDAAHGI NE AAHGIANEDA  GIANED
Sbjct: 183 GIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGIANED 242

Query: 289 AAQGIAHEDAVQGIANEDAVHGVAKE--------------VAAHGVANEDAAHAIAKPDA 334
           +   IA+EDA+  IAN D V G  K               +    +        + KP  
Sbjct: 243 SVYDIANEDAIYDIAN-DTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLTRTLYKPSL 301

Query: 335 AHGI-ANEVATQGIATED----------VADGIANEDAAHGVAKEVTAHGVANEDAVQGV 383
              +    + T    T            +    AN D  H +A E + + +ANE AV  +
Sbjct: 302 TRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIANEGAVYDI 361

Query: 384 VNE 386
            N+
Sbjct: 362 AND 364



 Score =  184 bits (467), Expect = 9e-46
 Identities = 112/248 (45%), Positives = 137/248 (55%), Gaps = 27/248 (10%)

Query: 1229 NEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQ 1288
            +E     I  ED +  I NEDA HG+ANE A  G + EDA QGIANEDAA GIA EDA Q
Sbjct: 123  HEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQ 182

Query: 1289 GIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANED 1348
            GIANE AAQGIA ED  QG+ANED +QG+ANE    G+A+EDA  GIANEDA HGIANED
Sbjct: 183  GIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGIANED 242

Query: 1349 AAQGIANEDAAQDIANEDAAQGISKED--------------AVQGIANEDAAQGIAKEDP 1394
            +   IANEDA  DIAN D  QG  K                 ++ +      + + K   
Sbjct: 243  SVYDIANEDAIYDIAN-DTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLTRTLYKPSL 301

Query: 1395 VQGVANEDAVQGVANEVEVQGV-----------AHEDAVQGIANEDAAHGIANEVAAHGI 1443
             + +     +        ++ +           A+ D V  IANED+ + IANE A + I
Sbjct: 302  TRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIANEGAVYDI 361

Query: 1444 ANEDAAQG 1451
            AN D  QG
Sbjct: 362  AN-DTVQG 368



 Score =  183 bits (465), Expect = 2e-45
 Identities = 114/252 (45%), Positives = 139/252 (55%), Gaps = 17/252 (6%)

Query: 1414 QGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANE 1473
            +   HED V  I NEDA+H I NE A HGIANE A +G ANEDAAQGIA+EDA  GIA+E
Sbjct: 119  ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASE 178

Query: 1474 DAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGV 1533
            DA  G+A EVAA G+ANEDAA  IA  DA +GIANE A  GIA ED A GIANEDA HG+
Sbjct: 179  DAAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGI 238

Query: 1534 ANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVV-------------N 1580
            ANE +   IANE A++ +A  D VQG +K             + +V              
Sbjct: 239  ANEDSVYDIANEDAIYDIA-NDTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLTRTLY 297

Query: 1581 EDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSI--ANKDAAQGIANQDAAQGIANEVA 1638
            + +L   +       A  K      +   +       AN D    IAN+D+   IANE A
Sbjct: 298  KPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIANEGA 357

Query: 1639 AHGISKEDAVQG 1650
             + I+  D VQG
Sbjct: 358  VYDIA-NDTVQG 368



 Score =  183 bits (464), Expect = 2e-45
 Identities = 96/146 (65%), Positives = 109/146 (74%), Gaps = 1/146 (0%)

Query: 991  QGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANE 1050
            +   +E  V  I ++DA   I NEDA HGIANE A  G ANEDAAQGIANEDAA GIA+E
Sbjct: 119  ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASE 178

Query: 1051 VAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGV 1110
             AA GI+ E A QGIANEDAAQGIANEDA QGIA+EDA  GIANEDA HG+A E A HG+
Sbjct: 179  DAAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGI 238

Query: 1111 ANEDPVQGVANEDAVQGVANEVEVQG 1136
            ANED V  +ANEDA+  +AN+  VQG
Sbjct: 239  ANEDSVYDIANEDAIYDIANDT-VQG 263



 Score =  181 bits (460), Expect = 6e-45
 Identities = 109/252 (43%), Positives = 139/252 (55%), Gaps = 17/252 (6%)

Query: 246 QGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANE 305
           +   HED V  I NEDA+H ITNE A HGIANE A +G ANEDAAQGIA+EDA  GIA+E
Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASE 178

Query: 306 DAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGV 365
           DA  G+A EVAA G+ANEDAA  IA  DA  GIANE A  GIA ED A GIANEDA HG+
Sbjct: 179 DAAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGI 238

Query: 366 AKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDA 425
           A E + + +ANEDA+  + N D + G +       ++ +      +   +    +     
Sbjct: 239 ANEDSVYDIANEDAIYDIAN-DTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLTRTLY 297

Query: 426 AQGIANEVAAHGIS----KEDAVQGI-----------ANEDAAQGIAHEDAAQGIAHEDA 470
              +   +    +     K   ++ +           AN D    IA+ED+   IA+E A
Sbjct: 298 KPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIANEGA 357

Query: 471 VQGIANEDAVHG 482
           V  IAN D V G
Sbjct: 358 VYDIAN-DTVQG 368



 Score =  181 bits (460), Expect = 6e-45
 Identities = 111/251 (44%), Positives = 134/251 (53%), Gaps = 16/251 (6%)

Query: 1721 QGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKE 1780
            +   HED V  I NEDA+H ITNE A HGIANE A +G A+EDA QGIANEDA H +A E
Sbjct: 119  ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASE 178

Query: 1781 VAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGI 1840
             AA G+ANE AA  IA  DAA+GIANE A QGIA ED A GI NEDAAHG+ANE A HGI
Sbjct: 179  DAAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGI 238

Query: 1841 SKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAA 1900
            + ED+V  IANEDA   IA  D +QG                + +        +      
Sbjct: 239  ANEDSVYDIANEDAIYDIA-NDTVQGTLKRTLYTTSLMRTPYKAL----VMRTLYMTSLT 293

Query: 1901 QGIANEDAAQDIANEDAAQGISKEDAVQGI-----------ANQDAAQGIAKEDAVQGIA 1949
            + +      + +          K   ++ +           AN D    IA ED+V  IA
Sbjct: 294  RTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIA 353

Query: 1950 NEDAAQGIANE 1960
            NE A   IAN+
Sbjct: 354  NEGAVYDIAND 364



 Score =  180 bits (457), Expect = 1e-44
 Identities = 93/142 (65%), Positives = 105/142 (73%)

Query: 652 HGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISK 711
           H    +ED    I   DA+H I NE A HGIANE A +G ANEDAAQGIANE AAHGI+ 
Sbjct: 118 HESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIAS 177

Query: 712 EDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQG 771
           EDA QGIANE AAQGIA+EDA QGIANEDAV G+A E AAHG+ANED   G+ANED V G
Sbjct: 178 EDAAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHG 237

Query: 772 VANEVEVQGIAHEDAVQGIANE 793
           +ANE  V  IA+EDA+  IAN+
Sbjct: 238 IANEDSVYDIANEDAIYDIAND 259



 Score =  180 bits (457), Expect = 1e-44
 Identities = 112/251 (44%), Positives = 133/251 (52%), Gaps = 27/251 (10%)

Query: 1776 SVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEV 1835
            S   E   H + NEDA+H I   DA  GIANE A +G A ED A GI NEDAAHG+A+E 
Sbjct: 120  STPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASED 179

Query: 1836 AAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIA 1895
            AA GI+ E A QGIANEDAAQGIA ED +QG+ANE    G+A+EDA  GIANEDA HGIA
Sbjct: 180  AAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGIA 239

Query: 1896 NEDAAQGIANEDAAQDIANEDAAQGISKED--------------AVQGIANQDAAQGIAK 1941
            NED+   IANEDA  DIAN D  QG  K                 ++ +      + + K
Sbjct: 240  NEDSVYDIANEDAIYDIAN-DTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLTRTLYK 298

Query: 1942 EDAVQGIANEDAAQGIANEVAAHGI-----------ANEDAAQGIANEDAAQGIAHEDAV 1990
                + +                 +           AN D    IANED+   IA+E AV
Sbjct: 299  PSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIANEGAV 358

Query: 1991 QGIANEDAVHG 2001
              IAN D V G
Sbjct: 359  YDIAN-DTVQG 368



 Score =  180 bits (457), Expect = 1e-44
 Identities = 119/256 (46%), Positives = 137/256 (53%), Gaps = 35/256 (13%)

Query: 215 EDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHG 274
           ED V  + NED    + NEDAV G+ANE   +G A+EDA QGIANEDAAHGI +E AA G
Sbjct: 124 EDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQG 183

Query: 275 IANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDA 334
           IANE AAQGIANEDAAQGIA+EDAVQGIANEDA         AHG+ANEDAAH IA  DA
Sbjct: 184 IANEVAAQGIANEDAAQGIANEDAVQGIANEDA---------AHGIANEDAAHGIANEDA 234

Query: 335 AHGIANEVATQGIATEDVADGIANEDAAHGVAKEVTAHGVANEDAVQGVV---------- 384
            HGIANE +   IA ED    IAN D   G  K             + +V          
Sbjct: 235 VHGIANEDSVYDIANEDAIYDIAN-DTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLT 293

Query: 385 ---NEDALHGVVANEDAAQAIAKPDAAHGI-----------ANEVAAHGIANEDAAQGIA 430
               + +L   +       A  K      +           AN    H IANED+   IA
Sbjct: 294 RTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIA 353

Query: 431 NEVAAHGISKEDAVQG 446
           NE A + I+  D VQG
Sbjct: 354 NEGAVYDIA-NDTVQG 368



 Score =  180 bits (457), Expect = 1e-44
 Identities = 112/255 (43%), Positives = 141/255 (55%), Gaps = 26/255 (10%)

Query: 907  EDVADGIA-KDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQG 965
            ED    I  +DA+H IT E+A   IA + A     NEDAAQG+ANEDAAHG+A+EDAAQG
Sbjct: 124  EDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQG 183

Query: 966  VANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVA 1025
            +ANEVAAQG+ANEDA  G+ANEDAVQG+ANE         DA  GIANEDAAHGIANE A
Sbjct: 184  IANEVAAQGIANEDAAQGIANEDAVQGIANE---------DAAHGIANEDAAHGIANEDA 234

Query: 1026 AHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANED----AAQGIANEDAAQ 1081
             HGIANED+   IANEDA   IAN+     + +      +          + +      +
Sbjct: 235  VHGIANEDSVYDIANEDAIYDIANDTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLTR 294

Query: 1082 GIAHEDAVQGIANEDAVHGVAKEVAAHGV-----------ANEDPVQGVANEDAVQGVAN 1130
             +      + +     +    K      +           AN D V  +ANED+V  +AN
Sbjct: 295  TLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIAN 354

Query: 1131 EVEVQGVAHEDAVQG 1145
            E  V  +A+ D VQG
Sbjct: 355  EGAVYDIAN-DTVQG 368



 Score =  179 bits (455), Expect = 2e-44
 Identities = 116/282 (41%), Positives = 145/282 (51%), Gaps = 33/282 (11%)

Query: 450 EDAAQGIAHEDAAQGIAHEDA----VQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPD 505
           E + + + H+D   G    +     V  + +E   H    E   H + N+DA+H I   D
Sbjct: 88  EASEESLVHKDRGDGERPVNVRVVQVAPLRHESTPH----EDTVHNITNEDASHDITNED 143

Query: 506 AARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIA 565
           A  GIANE A +G A ED A GIANEDA HG+A+E AA G+ANE AA  IA  DAA GIA
Sbjct: 144 AVHGIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQGIANEDAAQGIA 203

Query: 566 NEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQ 625
           NE A QGIA ED A GIANEDAAHG+ANE AVHG+A ED+V  +ANEDA++ +AN D  Q
Sbjct: 204 NEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIAN-DTVQ 262

Query: 626 GIAKEVTAHGVANEDAVQGVV-------------NEDALHGVVANEDAAQAIAKPDAAHG 672
           G  K             + +V              + +L   +       A  K      
Sbjct: 263 GTLKRTLYTTSLMRTPYKALVMRTLYMTSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRA 322

Query: 673 I-----------ANEVAAHGIANEDAAQGIANEDAAQGIANE 703
           +           AN    H IANED+   IANE A   IAN+
Sbjct: 323 LYTTLLMIPTRHANADTVHDIANEDSVYHIANEGAVYDIAND 364



 Score =  178 bits (452), Expect = 5e-44
 Identities = 107/248 (43%), Positives = 133/248 (53%), Gaps = 15/248 (6%)

Query: 120 QGVANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKE 179
           +   +ED V  + NEDA   + NEDAV GIANE A  G ANEDAAQGIANEDAA  IA E
Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASE 178

Query: 180 DAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGV 239
           DAAQ IANE AAQGI+ EDA QGIANEDA QGIA ED   G+ANED   G+ANEDAV G+
Sbjct: 179 DAAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGI 238

Query: 240 ANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANED----AAQGIANEDAAQGIAH 295
           ANE  V  +A+EDA+  IAN+     +   +    +          + +      + +  
Sbjct: 239 ANEDSVYDIANEDAIYDIANDTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLTRTLYK 298

Query: 296 EDAVQGIANEDAVHGVAKEVAAHGV-----------ANEDAAHAIAKPDAAHGIANEVAT 344
               + +     +    K      +           AN D  H IA  D+ + IANE A 
Sbjct: 299 PSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIANEGAV 358

Query: 345 QGIATEDV 352
             IA + V
Sbjct: 359 YDIANDTV 366



 Score =  178 bits (452), Expect = 5e-44
 Identities = 95/142 (66%), Positives = 109/142 (76%), Gaps = 2/142 (1%)

Query: 630 EVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQ 689
           E T H + NEDA   + NEDA+HG+ ANE A +  A  DAA GIANE AAHGIA+EDAAQ
Sbjct: 124 EDTVHNITNEDASHDITNEDAVHGI-ANEAADKGNANEDAAQGIANEDAAHGIASEDAAQ 182

Query: 690 GIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEV 749
           GIANE AAQGIANE AA GI+ EDAVQGIANEDAA GIA+EDA  GIANEDAVHG+A E 
Sbjct: 183 GIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGIANED 242

Query: 750 AAHGVANEDPVQGVANEDVVQG 771
           + + +ANED +  +AN D VQG
Sbjct: 243 SVYDIANEDAIYDIAN-DTVQG 263



 Score =  177 bits (448), Expect = 1e-43
 Identities = 91/142 (64%), Positives = 105/142 (73%), Gaps = 1/142 (0%)

Query: 607 QGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAK 666
           +   +ED VH + NEDA+  I  E   HG+ANE A +G  NEDA  G +ANEDAA  IA 
Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQG-IANEDAAHGIAS 177

Query: 667 PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG 726
            DAA GIANEVAA GIANEDAAQGIANEDA QGIANE AAHGI+ EDA  GIANEDA  G
Sbjct: 178 EDAAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHG 237

Query: 727 IAHEDAVQGIANEDAVHGVAKE 748
           IA+ED+V  IANEDA++ +A +
Sbjct: 238 IANEDSVYDIANEDAIYDIAND 259



 Score =  176 bits (445), Expect = 3e-43
 Identities = 116/277 (41%), Positives = 144/277 (51%), Gaps = 30/277 (10%)

Query: 1718 VEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSV 1777
            V+V  + HE       +ED  H ITNE A+H I NEDA  GIA+E A +G ANEDA    
Sbjct: 111  VQVAPLRHEST----PHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDA---- 162

Query: 1778 AKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAA 1837
                 A G+ANEDAAH IA  DAA+GIANEVAAQGIA ED A GI NEDA  G+ANE AA
Sbjct: 163  -----AQGIANEDAAHGIASEDAAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAA 217

Query: 1838 HGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANE 1897
            HGI+ EDA  GIANEDA  GIA ED +  +ANE  +  +A+ D VQG             
Sbjct: 218  HGIANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIAN-DTVQGTLKRTLYTTSLMR 276

Query: 1898 DAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGI--------- 1948
               + +      + +      + + K    + +          K   ++ +         
Sbjct: 277  TPYKAL----VMRTLYMTSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPT 332

Query: 1949 --ANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQG 1983
              AN D    IANE + + IANE A   IAN D  QG
Sbjct: 333  RHANADTVHDIANEDSVYHIANEGAVYDIAN-DTVQG 368



 Score =  172 bits (437), Expect = 3e-42
 Identities = 88/142 (61%), Positives = 103/142 (72%), Gaps = 1/142 (0%)

Query: 684 NEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVH 743
           +ED    I NEDA+  I NE A HGI+ E A +G ANEDAAQGIA+EDA  GIA+EDA  
Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQ 182

Query: 744 GVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEV 803
           G+A EVAA G+ANED  QG+ANED VQG+ANE    GIA+EDA  GIANEDA HGIANE 
Sbjct: 183 GIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGIANED 242

Query: 804 AAHGVANEDAAQGVANEDAAQG 825
           + + +ANEDA   +AN D  QG
Sbjct: 243 SVYDIANEDAIYDIAN-DTVQG 263



 Score =  171 bits (433), Expect = 8e-42
 Identities = 110/248 (44%), Positives = 132/248 (53%), Gaps = 18/248 (7%)

Query: 1761 HEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVAD 1820
            HED V  I NEDA H +  E A HG+ANE A    A  DAA+GIANE AA GIA+ED A 
Sbjct: 123  HEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQ 182

Query: 1821 GIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHED 1880
            GI NE AA G+ANE AA GI+ EDAVQGIANEDAA GIA ED   G+ANE  V G+A+ED
Sbjct: 183  GIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGIANED 242

Query: 1881 AVQGIANEDAAHGIANEDAAQGIANED--------------AAQDIANEDAAQGISKEDA 1926
            +V  IANEDA + IAN D  QG                     + +      + + K   
Sbjct: 243  SVYDIANEDAIYDIAN-DTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLTRTLYKPSL 301

Query: 1927 VQGIANQDAAQGIAKEDAVQGIANE--DAAQGIANEVAAHGIANEDAAQGIANEDAAQGI 1984
             + +          K   ++ +           AN    H IANED+   IANE A   I
Sbjct: 302  TRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIANEGAVYDI 361

Query: 1985 AHEDAVQG 1992
            A+ D VQG
Sbjct: 362  AN-DTVQG 368



 Score =  168 bits (425), Expect = 7e-41
 Identities = 107/246 (43%), Positives = 126/246 (51%), Gaps = 35/246 (14%)

Query: 505 DAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGI 564
           D    I NE A+  I  ED   GIANE A  G ANE AA G+ANEDAAH IA  DAA GI
Sbjct: 125 DTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQGI 184

Query: 565 ANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAA 624
           ANEVA QGIA ED A GIANEDA  G+ANE A HG+A EDA  G+ANEDAVHG+ANED+ 
Sbjct: 185 ANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGIANEDSV 244

Query: 625 QGIAKEVTAHGVANEDAVQGVVNEDA-------------LHGVVANEDAAQAIAKPDAAH 671
             IA E   + +AN D VQG +                 +   +      + + KP    
Sbjct: 245 YDIANEDAIYDIAN-DTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLTRTLYKPSLTR 303

Query: 672 GIANE--------------------VAAHGIANEDAAQGIANEDAAQGIANEVAAHGISK 711
            +                       +     AN D    IANED+   IANE A + I+ 
Sbjct: 304 TLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIANEGAVYDIA- 362

Query: 712 EDAVQG 717
            D VQG
Sbjct: 363 NDTVQG 368



 Score =  166 bits (420), Expect = 3e-40
 Identities = 104/247 (42%), Positives = 127/247 (51%), Gaps = 53/247 (21%)

Query: 1712 QGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANE 1771
            +   +E  V  + +EDA   I NEDA HGI NE A  G ANEDAAQGIA+EDA  GIA+E
Sbjct: 119  ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASE 178

Query: 1772 DAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGV 1831
            DA   +A EVAA G+ANEDAA  IA  DA +GIANE AA GIA ED A GI NEDA HG+
Sbjct: 179  DAAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGI 238

Query: 1832 ANEVAAHGISKEDAVQGIANEDAAQGIAKE------------------------------ 1861
            ANE + + I+ EDA+  IAN D  QG  K                               
Sbjct: 239  ANEDSVYDIANEDAIYDIAN-DTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLTRTLY 297

Query: 1862 --------------------DPIQGVANEVEVQGVAHEDA--VQGIANEDAAHGIANEDA 1899
                                 P++ +   + +    H +A  V  IANED+ + IANE A
Sbjct: 298  KPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIANEGA 357

Query: 1900 AQGIANE 1906
               IAN+
Sbjct: 358  VYDIAND 364



 Score =  162 bits (411), Expect = 3e-39
 Identities = 107/266 (40%), Positives = 135/266 (50%), Gaps = 32/266 (12%)

Query: 761  QGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANE 820
            +   +ED V  + NE     I +EDAV GIANE A  G ANE AA G+ANEDAA G+A+E
Sbjct: 119  ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASE 178

Query: 821  DAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQA 880
            DAAQG+ANE A  G+ANEDAAQG+A         NEDAVQG+ NE+A HG +ANEDAA  
Sbjct: 179  DAAQGIANEVAAQGIANEDAAQGIA---------NEDAVQGIANEDAAHG-IANEDAAHG 228

Query: 881  IAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEE--------------A 926
            IA  DA HGIANE      +   IA ED    IA D   G  K                 
Sbjct: 229  IANEDAVHGIANED-----SVYDIANEDAIYDIANDTVQGTLKRTLYTTSLMRTPYKALV 283

Query: 927  AQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGV--ANEDAVHGV 984
             + +       ++      + +               + +   +       AN D VH +
Sbjct: 284  MRTLYMTSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDI 343

Query: 985  ANEDAVQGVANEVEVQGIAHKDAIQG 1010
            ANED+V  +ANE  V  IA+ D +QG
Sbjct: 344  ANEDSVYHIANEGAVYDIAN-DTVQG 368



 Score =  162 bits (409), Expect = 5e-39
 Identities = 105/253 (41%), Positives = 134/253 (52%), Gaps = 23/253 (9%)

Query: 869  HGVVANEDAAQAIAKPDAAHGIANE----GVANEVAAQGIATEDVADGIA-KDAAHGITK 923
            H    +ED    I   DA+H I NE    G+ANE A +G A ED A GIA +DAAHGI  
Sbjct: 118  HESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIAS 177

Query: 924  EEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHG 983
            E+AAQ IA + AA  I NEDAAQG+ANEDA  G+ANEDAA G+ANE AA G+ANEDAVHG
Sbjct: 178  EDAAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHG 237

Query: 984  VANEDAVQGVANEVEVQGIAHKDAIQG-----IANEDAAHGIANEVAAHGIANEDAAQGI 1038
            +ANED+V  +ANE  +  IA+ D +QG     +            +    +      + +
Sbjct: 238  IANEDSVYDIANEDAIYDIAN-DTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLTRTL 296

Query: 1039 ANEDAAQGIANEVAAHGISKEDAVQGI-----------ANEDAAQGIANEDAAQGIAHED 1087
                  + +          K   ++ +           AN D    IANED+   IA+E 
Sbjct: 297  YKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIANEG 356

Query: 1088 AVQGIANEDAVHG 1100
            AV  IAN D V G
Sbjct: 357  AVYDIAN-DTVQG 368



 Score =  161 bits (407), Expect = 8e-39
 Identities = 85/142 (59%), Positives = 99/142 (69%), Gaps = 6/142 (4%)

Query: 1995 NEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQ 2054
            +ED VH + NEDA+H I   DA  GIANE A +G A ED A GIANEDAAHG+A+EDAAQ
Sbjct: 123  HEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQ 182

Query: 2055 AIAKPDAAHGIANEGIATEDVADGIA-EDAVQGITNEEAAQAIAKQDAAHGITKEDAAQG 2113
             IA   AA GIANE     D A GIA EDAVQGI NE+AA  IA +DAAHGI  EDA  G
Sbjct: 183  GIANEVAAQGIANE-----DAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHG 237

Query: 2114 VTNEVAAQGVANEDAAHGVANE 2135
            + NE +   +ANEDA + +AN+
Sbjct: 238  IANEDSVYDIANEDAIYDIAND 259



 Score = 34.3 bits (77), Expect = 1.5
 Identities = 16/37 (43%), Positives = 22/37 (59%), Gaps = 1/37 (2%)

Query: 827 ANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVV 863
           AN D VH +ANED+   +A E   + + N D VQG +
Sbjct: 335 ANADTVHDIANEDSVYHIANEGAVYDIAN-DTVQGTL 370



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 18/38 (47%), Positives = 22/38 (57%), Gaps = 1/38 (2%)

Query: 1994 ANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIAT 2031
            AN D VH +ANED+ + IA   A   IAN+   QG  T
Sbjct: 335  ANADTVHDIANEDSVYHIANEGAVYDIAND-TVQGTLT 371



 Score = 32.3 bits (72), Expect = 5.7
 Identities = 14/37 (37%), Positives = 21/37 (56%)

Query: 818 ANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVT 854
           AN D    +ANED+V+ +ANE A   +A +     +T
Sbjct: 335 ANADTVHDIANEDSVYHIANEGAVYDIANDTVQGTLT 371


>gi|239746650 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 486

 Score =  362 bits (930), Expect = 2e-99
 Identities = 191/305 (62%), Positives = 220/305 (72%), Gaps = 23/305 (7%)

Query: 2088 TNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAA 2147
            T E + +++  +D   G    +        +  +   +ED  H + NE A+H + NEDA 
Sbjct: 86   TLEASEESLVHKDRGDGERPVNVKVVQVAPLRRESTPHEDTVHNITNEDASHDITNEDAV 145

Query: 2148 QGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANE 2207
             G+ANE A +G+ANEDA QG+ANE         DA  GIA+EDAAQG+ANEVAA G+ANE
Sbjct: 146  HGIANEAADKGIANEDAAQGIANE---------DAAHGIASEDAAQGIANEVAAQGIANE 196

Query: 2208 DAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANE------ 2261
            DAAQG+A E AA G+ANEDAA G+ANE AVHG+ANED+   +A EDA   IAN+      
Sbjct: 197  DAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIANDTVQGTL 256

Query: 2262 --------DAAHGIANEDAVHGIANEDAVYDIANDTVQGTLTRTLYRTSLMRTPYKASVM 2313
                    D  H IANED+V+ IANE AVYDIANDTVQGTLTRTLY TSLMRTPYKASVM
Sbjct: 257  TRTLHANVDTVHDIANEDSVYDIANEGAVYDIANDTVQGTLTRTLYTTSLMRTPYKASVM 316

Query: 2314 RTLYTTSLTRTPYKPSLTRTLYTTSLMRAPYKTSPMRALYTTLLMIPTRHANADTVHDIA 2373
            RTLYTTSLTRTPYKPSLTRTLYTTSLM APYKTSPMRALYTTLLMIPTRHA  D VHDIA
Sbjct: 317  RTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALYTTLLMIPTRHAIVDAVHDIA 376

Query: 2374 NEDTV 2378
            NED+V
Sbjct: 377  NEDSV 381



 Score =  359 bits (921), Expect = 2e-98
 Identities = 201/377 (53%), Positives = 233/377 (61%), Gaps = 51/377 (13%)

Query: 2040 NEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQ 2099
            +ED  H + NEDA+  I   DA HGIANE              A +GI NE+AAQ IA +
Sbjct: 123  HEDTVHNITNEDASHDITNEDAVHGIANEA-------------ADKGIANEDAAQGIANE 169

Query: 2100 DAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGV 2159
            DAAHGI  EDAAQG+ NEVAAQG+ANEDAA G+A E AAHG+ANEDAA G+ANE A  G+
Sbjct: 170  DAAHGIASEDAAQGIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGI 229

Query: 2160 ANEDAVQGVANEVEVQGIAHK--------------DAIQGIANEDAAQGVANEVAAHGVA 2205
            ANED+V  +ANE  +  IA+               D +  IANED+   +ANE A + +A
Sbjct: 230  ANEDSVYDIANEDAIYDIANDTVQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYDIA 289

Query: 2206 NEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGI------- 2258
            N+     +   +    +        V   +    +        + +      +       
Sbjct: 290  NDTVQGTLTRTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKT 349

Query: 2259 -----------------ANEDAAHGIANEDAVHGIANEDAVYDIANDTVQGTLTRTLYRT 2301
                             A  DA H IANED+V+ IANE AVYDIANDTVQGTLTRTLY T
Sbjct: 350  SPMRALYTTLLMIPTRHAIVDAVHDIANEDSVYDIANEGAVYDIANDTVQGTLTRTLYTT 409

Query: 2302 SLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMRAPYKTSPMRALYTTLLMIPT 2361
            SLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLM APYKTSPMRALYTTLLMIPT
Sbjct: 410  SLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPT 469

Query: 2362 RHANADTVHDIANEDTV 2378
            RHAN D VHDIANEDTV
Sbjct: 470  RHANVDAVHDIANEDTV 486



 Score =  273 bits (699), Expect = 1e-72
 Identities = 166/318 (52%), Positives = 199/318 (62%), Gaps = 29/318 (9%)

Query: 16  SSEESLVHKDRGDGERPVNVRVVQVAPLRHESTPYEDTVHDIANEDADAAHGITNEDAVQ 75
           +SEESLVHKDRGDGERPVNV+VVQVAPLR ESTP+EDTVH+I NEDA  +H ITNEDAV 
Sbjct: 89  ASEESLVHKDRGDGERPVNVKVVQVAPLRRESTPHEDTVHNITNEDA--SHDITNEDAVH 146

Query: 76  GVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANED 135
           G+ANE A +G+ANEDAA G+ANE AAHG+A+EDAAQG+ANEVAAQG+ANEDA QG+A ED
Sbjct: 147 GIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQGIANEDAAQGIAKED 206

Query: 136 AVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDI-----ANEDA 190
           A  G+ANEDA  GIANEDA HGIANED+   IANEDA  DIA +     +     AN D 
Sbjct: 207 AAHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIANDTVQGTLTRTLHANVDT 266

Query: 191 AQGISKEDAVQGIANEDAAQGIAKEDPVQGVANE----DPVQGVANEDAVQGVANEVEVQ 246
              I+ ED+V  IANE A   IA  D VQG          +     + +V        + 
Sbjct: 267 VHDIANEDSVYDIANEGAVYDIA-NDTVQGTLTRTLYTTSLMRTPYKASVMRTLYTTSLT 325

Query: 247 GVAHEDAVQGIANEDA---AHGITNEVAA-----------HGIANEDAAQGIANEDAAQG 292
              ++ ++       +   A   T+ + A           H I   DA   IANED+   
Sbjct: 326 RTPYKPSLTRTLYTTSLMMAPYKTSPMRALYTTLLMIPTRHAIV--DAVHDIANEDSVYD 383

Query: 293 IAHEDAVQGIANEDAVHG 310
           IA+E AV  IAN D V G
Sbjct: 384 IANEGAVYDIAN-DTVQG 400



 Score =  212 bits (540), Expect = 3e-54
 Identities = 133/281 (47%), Positives = 161/281 (57%), Gaps = 16/281 (5%)

Query: 1004 HKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQ 1063
            H+D +  I NEDA+H I NE A HGIANE A +GIANEDAAQGIANE AAHGI+ EDA Q
Sbjct: 123  HEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQ 182

Query: 1064 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANED 1123
            GIANE AAQGIANEDAAQGIA EDA  GIANEDA HG+A E A HG+ANED V  +ANED
Sbjct: 183  GIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242

Query: 1124 AVQGVANEVEVQGV------AHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQG----- 1172
            A+  +AN+  VQG       A+ D V  IANED+ + IANE A + IAN D  QG     
Sbjct: 243  AIYDIANDT-VQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYDIAN-DTVQGTLTRT 300

Query: 1173 IANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANE-- 1230
            +      +       ++ +          K      +       A  K    R +     
Sbjct: 301  LYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALYTTLL 360

Query: 1231 VAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQG 1271
            +     A  D    IANED+ + +ANE A + I+  D VQG
Sbjct: 361  MIPTRHAIVDAVHDIANEDSVYDIANEGAVYDIA-NDTVQG 400



 Score =  204 bits (519), Expect = 8e-52
 Identities = 130/282 (46%), Positives = 160/282 (56%), Gaps = 29/282 (10%)

Query: 933  QDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQG 992
            +D  H+ITNEDA+  + NEDA HG+ANE A +G+ANE AAQG+ANEDA HG+A+EDA QG
Sbjct: 124  EDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQG 183

Query: 993  VANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVA 1052
            +ANEV  QGIA++DA QGIA EDAAHGIANE AAHGIANEDA  GIANED+   IANE A
Sbjct: 184  IANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDA 243

Query: 1053 AHGISKEDAVQGI------ANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVA 1106
             + I+  D VQG       AN D    IANED+   IA+E AV  IAN D V G      
Sbjct: 244  IYDIA-NDTVQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYDIAN-DTVQGTLTRTL 301

Query: 1107 AHGVANEDP----VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDA----------- 1151
                    P    V       ++     +  +    +  ++     + +           
Sbjct: 302  YTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALYTTLLM 361

Query: 1152 ---AHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQG 1190
                H I +  A H IANED+   IANE A   IA+ D VQG
Sbjct: 362  IPTRHAIVD--AVHDIANEDSVYDIANEGAVYDIAN-DTVQG 400



 Score =  201 bits (511), Expect = 7e-51
 Identities = 130/298 (43%), Positives = 161/298 (54%), Gaps = 20/298 (6%)

Query: 1874 QGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQ 1933
            +   HED V  I NEDA+H I NEDA  GIANE A + IANEDAAQGI+ EDA  GIA++
Sbjct: 119  ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASE 178

Query: 1934 DAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGI 1993
            DAAQGIA E A QGIANEDAAQGIA E AAHGIANEDAA GIANEDA  GIA+ED+V  I
Sbjct: 179  DAAQGIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDI 238

Query: 1994 ANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAA 2053
            ANEDA++ +AN          D  +G          A  D    IANED+ + +ANE A 
Sbjct: 239  ANEDAIYDIAN----------DTVQGTLTRTLH---ANVDTVHDIANEDSVYDIANEGAV 285

Query: 2054 QAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGI--TKEDAA 2111
              IA       +      T  +        ++ +      +   K      +  T    A
Sbjct: 286  YDIANDTVQGTLTRTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMA 345

Query: 2112 QGVTNEVAA--QGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQG 2167
               T+ + A    +      H + +  A H +ANED+   +ANE A   +AN D VQG
Sbjct: 346  PYKTSPMRALYTTLLMIPTRHAIVD--AVHDIANEDSVYDIANEGAVYDIAN-DTVQG 400



 Score =  200 bits (509), Expect = 1e-50
 Identities = 131/285 (45%), Positives = 158/285 (55%), Gaps = 24/285 (8%)

Query: 1590 NEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQ 1649
            +ED    I   DA+H I NE A H IAN+ A +GIAN+DAAQGIANE AAHGI+ EDA Q
Sbjct: 123  HEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQ 182

Query: 1650 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANED 1709
            GIANE AAQGIANEDAAQGIA EDA  GIANEDA HG+A E A HG+ANED V  +ANED
Sbjct: 183  GIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242

Query: 1710 AVQGVANEVEVQGV------AHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHED 1763
            A+  +AN+  VQG       A+ D V  IANED+ + I NE A + IAN D  QG     
Sbjct: 243  AIYDIANDT-VQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYDIAN-DTVQG----T 296

Query: 1764 AVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGI-------ANEVAAQGIATE 1816
              + +     + +  K      +          KP   R +       A    +   A  
Sbjct: 297  LTRTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALY 356

Query: 1817 DVADGIPNE----DAAHGVANEVAAHGISKEDAVQGIANEDAAQG 1857
                 IP      DA H +ANE + + I+ E AV  IAN D  QG
Sbjct: 357  TTLLMIPTRHAIVDAVHDIANEDSVYDIANEGAVYDIAN-DTVQG 400



 Score =  197 bits (502), Expect = 8e-50
 Identities = 127/287 (44%), Positives = 156/287 (54%), Gaps = 9/287 (3%)

Query: 1346 NEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQ 1405
            +ED    I NEDA+ DI NEDA  GI+ E A +GIANEDAAQGIA ED   G+A+EDA Q
Sbjct: 123  HEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQ 182

Query: 1406 GVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHED 1465
            G+ANEV  QG+A+EDA QGIA EDAAHGIANE AAHGIANEDA  GIANED+   IA+ED
Sbjct: 183  GIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242

Query: 1466 AVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIA 1525
            A+  IAN D V G          AN D  H IA  D+   IANE A   IA + V   + 
Sbjct: 243  AIYDIAN-DTVQGTLTRTLH---ANVDTVHDIANEDSVYDIANEGAVYDIANDTVQGTLT 298

Query: 1526 NEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALH 1585
                   +        +   +    +        + +  T +  +   A        AL+
Sbjct: 299  RTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTR--TLYTTSLMMAPYKTSPMRALY 356

Query: 1586 SVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQG 1632
            + +       AI   DA H IANE + + IAN+ A   IAN D  QG
Sbjct: 357  TTLLMIPTRHAIV--DAVHDIANEDSVYDIANEGAVYDIAN-DTVQG 400



 Score =  197 bits (502), Expect = 8e-50
 Identities = 125/276 (45%), Positives = 151/276 (54%), Gaps = 49/276 (17%)

Query: 1843 EDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQG 1902
            ED V  I NEDA+  I  ED + G+ANE   +G+A+EDA QGIANEDAAHGIA+EDAAQG
Sbjct: 124  EDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQG 183

Query: 1903 IANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVA 1962
            IANE AAQ IANEDAAQGI+KEDA  GIAN+DAA GIA EDAV GIANED+   IANE A
Sbjct: 184  IANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDA 243

Query: 1963 AHGIANEDAAQGI------ANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIA---- 2012
             + IAN D  QG       AN D    IA+ED+V  IANE AV+ +AN+     +     
Sbjct: 244  IYDIAN-DTVQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYDIANDTVQGTLTRTLY 302

Query: 2013 ---------------------------KPDAARGI-----------ANEVAAQGIATEDV 2034
                                       KP   R +            + + A       +
Sbjct: 303  TTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALYTTLLMI 362

Query: 2035 ADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGI 2070
                A  DA H +ANED+   IA   A + IAN+ +
Sbjct: 363  PTRHAIVDAVHDIANEDSVYDIANEGAVYDIANDTV 398



 Score =  195 bits (496), Expect = 4e-49
 Identities = 126/287 (43%), Positives = 156/287 (54%), Gaps = 24/287 (8%)

Query: 1292 NEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQ 1351
            +ED    I  ED    + NED + G+ANE   +G+A+EDA QGIANEDAAHGIA+EDAAQ
Sbjct: 123  HEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQ 182

Query: 1352 GIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEV 1411
            GIANE AAQ IANEDAAQGI+KEDA  GIANEDAA GIA ED V G+ANED+V  +ANE 
Sbjct: 183  GIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242

Query: 1412 EVQGVAHEDAVQGI------ANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHED 1465
             +  +A+ D VQG       AN D  H IANE + + IANE A   IAN D  QG     
Sbjct: 243  AIYDIAN-DTVQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYDIAN-DTVQG----T 296

Query: 1466 AVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGI-----------ANEVATQG 1514
              + +     +    K      +          KP   R +            + +    
Sbjct: 297  LTRTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALY 356

Query: 1515 IATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVV 1561
                 +    A  DA H +ANE +   IANE AV+ +A  D VQG +
Sbjct: 357  TTLLMIPTRHAIVDAVHDIANEDSVYDIANEGAVYDIA-NDTVQGTL 402



 Score =  194 bits (492), Expect = 1e-48
 Identities = 124/286 (43%), Positives = 157/286 (54%), Gaps = 30/286 (10%)

Query: 385 NEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAV 444
           +ED +H +  NEDA+  I   DA HGIANE A  GIANEDAAQGIANE AAHGI+ EDA 
Sbjct: 123 HEDTVHNIT-NEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAA 181

Query: 445 QGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKP 504
           QGIANE AAQGIA+EDAAQGIA EDA  GIANEDA HG+A E A HG+AN+D+ + IA  
Sbjct: 182 QGIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANE 241

Query: 505 DAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGI 564
           DA   IAN+   QG  T  +    AN D VH +ANE + + +ANE A + IA       +
Sbjct: 242 DAIYDIANDTV-QGTLTRTLH---ANVDTVHDIANEDSVYDIANEGAVYDIANDTVQGTL 297

Query: 565 ANEVATQGIATEDVADGIANE----------------DAAHGVANEVAVHGVAIEDAVQG 608
              + T  +        +                      +  +  +A +  +   A+  
Sbjct: 298 TRTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALYT 357

Query: 609 V--------ANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVV 646
                    A  DAVH +ANED+   IA E   + +AN D VQG +
Sbjct: 358 TLLMIPTRHAIVDAVHDIANEDSVYDIANEGAVYDIAN-DTVQGTL 402



 Score =  193 bits (491), Expect = 1e-48
 Identities = 110/211 (52%), Positives = 138/211 (65%), Gaps = 6/211 (2%)

Query: 940  TNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEV 999
            T E + + + ++D   G    +        +  +   +ED VH + NEDA   + NE  V
Sbjct: 86   TLEASEESLVHKDRGDGERPVNVKVVQVAPLRRESTPHEDTVHNITNEDASHDITNEDAV 145

Query: 1000 QGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKE 1059
             GIA++ A +GIANEDAA GIANE AAHGIA+EDAAQGIANE AAQGIANE AA GI+KE
Sbjct: 146  HGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQGIANEDAAQGIAKE 205

Query: 1060 DAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGV-----ANED 1114
            DA  GIANEDAA GIANEDA  GIA+ED+V  IANEDA++ +A +     +     AN D
Sbjct: 206  DAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIANDTVQGTLTRTLHANVD 265

Query: 1115 PVQGVANEDAVQGVANEVEVQGVAHEDAVQG 1145
             V  +ANED+V  +ANE  V  +A+ D VQG
Sbjct: 266  TVHDIANEDSVYDIANEGAVYDIAN-DTVQG 295



 Score =  192 bits (488), Expect = 3e-48
 Identities = 133/384 (34%), Positives = 184/384 (47%), Gaps = 25/384 (6%)

Query: 246 QGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANE 305
           +   HED V  I NEDA+H ITNE A HGIANE A +GIANEDAAQGIA+EDA  GIA+E
Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASE 178

Query: 306 DAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGV 365
           DA  G+A EVAA G+ANEDAA  IAK DAAHGIAN         ED A GIANEDA HG+
Sbjct: 179 DAAQGIANEVAAQGIANEDAAQGIAKEDAAHGIAN---------EDAAHGIANEDAVHGI 229

Query: 366 AKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDA 425
           A E + + +ANEDA+  + N D + G +         A  D  H IANE + + IANE A
Sbjct: 230 ANEDSVYDIANEDAIYDIAN-DTVQGTLTR----TLHANVDTVHDIANEDSVYDIANEGA 284

Query: 426 AQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAK 485
              IAN+     +++      +        +        +        +     ++  + 
Sbjct: 285 VYDIANDTVQGTLTRTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTR--TLYTTSL 342

Query: 486 EVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHG 545
            +A +  +   A +        R    + A   IA ED    IANE AV+ +AN+     
Sbjct: 343 MMAPYKTSPMRALYTTLLMIPTRHAIVD-AVHDIANEDSVYDIANEGAVYDIANDTVQGT 401

Query: 546 VANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANE-------DAAHGVANEVAVH 598
           +       ++ +      +   + T  +        +           A +  +   A++
Sbjct: 402 LTRTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMTAPYKTSPMRALY 461

Query: 599 GVAIEDAVQGVANEDAVHGVANED 622
              +    +  AN DAVH +ANED
Sbjct: 462 TTLLMIPTRH-ANVDAVHDIANED 484



 Score =  192 bits (488), Expect = 3e-48
 Identities = 123/280 (43%), Positives = 152/280 (54%), Gaps = 23/280 (8%)

Query: 1166 NEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAR 1225
            +ED    I NEDA+  I +EDAV GIANE A  G+A E AA G+ANEDAAH IA  DAA+
Sbjct: 123  HEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQ 182

Query: 1226 GIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKED 1285
            GIANEVAAQGIA ED A GIA EDAAHG+ANE AAHGI+ EDAV GIANED+   IA ED
Sbjct: 183  GIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242

Query: 1286 AVQGIANEDAAQGI------AKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANED 1339
            A+  IAN D  QG       A  D V  +ANED +  +ANE  V  +A+ D VQG     
Sbjct: 243  AIYDIAN-DTVQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYDIAN-DTVQGTLTRT 300

Query: 1340 AAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGV- 1398
                +      +        + +      +   K    + +          K  P++ + 
Sbjct: 301  ----LYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALY 356

Query: 1399 ----------ANEDAVQGVANEVEVQGVAHEDAVQGIANE 1428
                      A  DAV  +ANE  V  +A+E AV  IAN+
Sbjct: 357  TTLLMIPTRHAIVDAVHDIANEDSVYDIANEGAVYDIAND 396



 Score =  191 bits (486), Expect = 6e-48
 Identities = 106/175 (60%), Positives = 121/175 (69%), Gaps = 8/175 (4%)

Query: 657 NEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQ 716
           +ED    I   DA+H I NE A HGIANE A +GIANEDAAQGIANE AAHGI+ EDA Q
Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQ 182

Query: 717 GIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEV 776
           GIANE AAQGIA+EDA QGIA EDA HG+A E AAHG+ANED V G+ANED V  +ANE 
Sbjct: 183 GIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242

Query: 777 EVQGIAHEDAVQGI------ANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQG 825
            +  IA+ D VQG       AN D  H IANE + + +ANE A   +AN D  QG
Sbjct: 243 AIYDIAN-DTVQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYDIAN-DTVQG 295



 Score =  191 bits (486), Expect = 6e-48
 Identities = 122/284 (42%), Positives = 148/284 (52%), Gaps = 23/284 (8%)

Query: 179 EDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQG 238
           ED   +I NEDA+  I+ EDAV GIANE A +GIA ED  QG+ANED   G+A+EDA QG
Sbjct: 124 EDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQG 183

Query: 239 VANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDA 298
           +ANEV  QG+A+EDA QGIA EDAAHGI NE AAHGIANEDA  GIANED+   IA+EDA
Sbjct: 184 IANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDA 243

Query: 299 VQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIAN 358
           +  IAN D V G          AN D  H IA  D+ + IANE A   IA + V   +  
Sbjct: 244 IYDIAN-DTVQGTLTRTLH---ANVDTVHDIANEDSVYDIANEGAVYDIANDTVQGTLTR 299

Query: 359 EDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKP------------- 405
                 + +      V        +        +         +  P             
Sbjct: 300 TLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALYTTL 359

Query: 406 ---DAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQG 446
                 H I +  A H IANED+   IANE A + I+  D VQG
Sbjct: 360 LMIPTRHAIVD--AVHDIANEDSVYDIANEGAVYDIA-NDTVQG 400



 Score =  191 bits (486), Expect = 6e-48
 Identities = 118/280 (42%), Positives = 150/280 (53%), Gaps = 11/280 (3%)

Query: 712 EDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQG 771
           ED V  I NEDA+  I +EDAV GIANE A  G+A E AA G+ANED   G+A+ED  QG
Sbjct: 124 EDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQG 183

Query: 772 VANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDA 831
           +ANEV  QGIA+EDA QGIA EDAAHGIANE AAHG+ANEDA  G+ANED+   +ANEDA
Sbjct: 184 IANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDA 243

Query: 832 VHGVANEDAAQGV------AKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPD 885
           ++ +AN D  QG       A   T H + NED+V  + NE A++  +AN+     + +  
Sbjct: 244 IYDIAN-DTVQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYD-IANDTVQGTLTRTL 301

Query: 886 AAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSI--TNED 943
               +        V      T              +       A  K     ++  T   
Sbjct: 302 YTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALYTTLLM 361

Query: 944 AAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHG 983
                A  DA H +ANED+   +ANE A   +AN D V G
Sbjct: 362 IPTRHAIVDAVHDIANEDSVYDIANEGAVYDIAN-DTVQG 400



 Score =  191 bits (485), Expect = 7e-48
 Identities = 106/176 (60%), Positives = 123/176 (69%), Gaps = 9/176 (5%)

Query: 647 NEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAA 706
           +ED +H +  NEDA+  I   DA HGIANE A  GIANEDAAQGIANEDAA GIA+E AA
Sbjct: 123 HEDTVHNIT-NEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAA 181

Query: 707 HGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANE 766
            GI+ E A QGIANEDAAQGIA EDA  GIANEDA HG+A E A HG+ANED V  +ANE
Sbjct: 182 QGIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANE 241

Query: 767 DVVQGVANEVEVQGI------AHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQG 816
           D +  +AN+  VQG       A+ D V  IANED+ + IANE A + +AN D  QG
Sbjct: 242 DAIYDIANDT-VQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYDIAN-DTVQG 295



 Score =  190 bits (482), Expect = 2e-47
 Identities = 122/281 (43%), Positives = 144/281 (51%), Gaps = 22/281 (7%)

Query: 1865 QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKE 1924
            +   +E  V  + +EDA   I NEDA HGIANE A +GIANEDAAQ IANEDAA GI+ E
Sbjct: 119  ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASE 178

Query: 1925 DAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGI 1984
            DA QGIAN+ AAQGIA EDA QGIA EDAA GIANE AAHGIANEDA  GIANED+   I
Sbjct: 179  DAAQGIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDI 238

Query: 1985 AHEDAVQGIANEDAVHGV------ANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGI 2038
            A+EDA+  IAN D V G       AN D  H IA  D+   IANE A   IA + V   +
Sbjct: 239  ANEDAIYDIAN-DTVQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYDIANDTVQGTL 297

Query: 2039 A-------------NEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQ 2085
                                 +      +   KP     +    +               
Sbjct: 298  TRTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALYT 357

Query: 2086 GITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANE 2126
             +       AI   DA H I  ED+   + NE A   +AN+
Sbjct: 358  TLLMIPTRHAIV--DAVHDIANEDSVYDIANEGAVYDIAND 396



 Score =  189 bits (479), Expect = 4e-47
 Identities = 117/282 (41%), Positives = 155/282 (54%), Gaps = 13/282 (4%)

Query: 1324 QGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANE 1383
            +   HED V  I NEDA+H I NEDA  GIANE A + IANEDAAQGI+ EDA  GIA+E
Sbjct: 119  ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASE 178

Query: 1384 DAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGI 1443
            DAAQGIA E   QG+ANEDA QG+A E    G+A+EDA  GIANEDA HGIANE + + I
Sbjct: 179  DAAQGIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDI 238

Query: 1444 ANEDAAQGIANEDAAQGI------AHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAI 1497
            ANEDA   IAN D  QG       A+ D V  IANED+V+ +A E A + +AN+     +
Sbjct: 239  ANEDAIYDIAN-DTVQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYDIANDTVQGTL 297

Query: 1498 AKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAV 1557
             +      +        +        +        +   +    +   +A +  +   A+
Sbjct: 298  TRTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLM--MAPYKTSPMRAL 355

Query: 1558 QGVVKEV-TAHGVANEDAVQGVVNEDALHSVVANEDAAQAIA 1598
               +  + T H +   DAV  + NED+++  +ANE A   IA
Sbjct: 356  YTTLLMIPTRHAIV--DAVHDIANEDSVYD-IANEGAVYDIA 394



 Score =  188 bits (478), Expect = 5e-47
 Identities = 107/179 (59%), Positives = 120/179 (67%), Gaps = 8/179 (4%)

Query: 1135 QGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANE 1194
            +   HED V  I NEDA+H I NE A HGIANE A +GIANEDAAQGIA+EDA  GIA+E
Sbjct: 119  ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASE 178

Query: 1195 DAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGV 1254
            DA  G+A EVAA G+ANEDAA  IAK DAA GIANE AA GIA ED   GIANED+ + +
Sbjct: 179  DAAQGIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDI 238

Query: 1255 ANEVAAHGISKEDAVQGI------ANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQG 1307
            ANE A + I+  D VQG       AN D    IA ED+V  IANE A   IA  D VQG
Sbjct: 239  ANEDAIYDIA-NDTVQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYDIA-NDTVQG 295



 Score =  187 bits (475), Expect = 1e-46
 Identities = 113/279 (40%), Positives = 152/279 (54%), Gaps = 12/279 (4%)

Query: 219 QGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANE 278
           +   +ED V  + NEDA   + NE  V G+A+E A +GIANEDAA GI NE AAHGIA+E
Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASE 178

Query: 279 DAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGI 338
           DAAQGIANE AAQGIA+EDA QGIA EDA HG+A E AAHG+ANEDA H IA  D+ + I
Sbjct: 179 DAAQGIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDI 238

Query: 339 ANEVATQGIATEDVADGI-----ANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVV 393
           ANE A   IA + V   +     AN D  H +A E + + +ANE AV  + N D + G +
Sbjct: 239 ANEDAIYDIANDTVQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYDIAN-DTVQGTL 297

Query: 394 ANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGIS----KEDAVQGIAN 449
                  ++ +      +   +    +        +   +    +     K   ++ +  
Sbjct: 298 TRTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALYT 357

Query: 450 EDAAQGIAHE--DAAQGIAHEDAVQGIANEDAVHGVAKE 486
                   H   DA   IA+ED+V  IANE AV+ +A +
Sbjct: 358 TLLMIPTRHAIVDAVHDIANEDSVYDIANEGAVYDIAND 396



 Score =  186 bits (473), Expect = 2e-46
 Identities = 107/183 (58%), Positives = 122/183 (66%), Gaps = 6/183 (3%)

Query: 607 QGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAK 666
           +   +ED VH + NEDA+  I  E   HG+ANE A +G+ NEDA  G +ANEDAA  IA 
Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQG-IANEDAAHGIAS 177

Query: 667 PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG 726
            DAA GIANEVAA GIANEDAAQGIA EDAA GIANE AAHGI+ EDAV GIANED+   
Sbjct: 178 EDAAQGIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYD 237

Query: 727 IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDA 786
           IA+EDA+  IAN D V G          AN D V  +ANED V  +ANE  V  IA+ D 
Sbjct: 238 IANEDAIYDIAN-DTVQGTLTRTLH---ANVDTVHDIANEDSVYDIANEGAVYDIAN-DT 292

Query: 787 VQG 789
           VQG
Sbjct: 293 VQG 295



 Score =  185 bits (470), Expect = 4e-46
 Identities = 123/288 (42%), Positives = 151/288 (52%), Gaps = 22/288 (7%)

Query: 1721 QGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKE 1780
            +   HED V  I NEDA+H ITNE A HGIANE A +GIA+EDA QGIANEDA H +A E
Sbjct: 119  ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASE 178

Query: 1781 VAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGI 1840
             AA G+ANE AA  IA  DAA+GIA E AA GIA ED A GI NEDA HG+ANE + + I
Sbjct: 179  DAAQGIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDI 238

Query: 1841 SKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAA 1900
            + EDA+  IAN D  QG          AN   V  +A+ED+V  IANE A + IAN D  
Sbjct: 239  ANEDAIYDIAN-DTVQGTLTRTL---HANVDTVHDIANEDSVYDIANEGAVYDIAN-DTV 293

Query: 1901 QGIANE--------------DAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQ 1946
            QG                     + +      +   K    + +          K   ++
Sbjct: 294  QGTLTRTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMR 353

Query: 1947 GIANEDAAQGIANEV--AAHGIANEDAAQGIANEDAAQGIAHEDAVQG 1992
             +          + +  A H IANED+   IANE A   IA+ D VQG
Sbjct: 354  ALYTTLLMIPTRHAIVDAVHDIANEDSVYDIANEGAVYDIAN-DTVQG 400



 Score =  185 bits (470), Expect = 4e-46
 Identities = 120/285 (42%), Positives = 153/285 (53%), Gaps = 23/285 (8%)

Query: 449 NEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAAR 508
           +ED    I +EDA+  I +EDAV GIANE A  G+A E AA G+AN+DAAH IA  DAA+
Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQ 182

Query: 509 GIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEV 568
           GIANEVAAQGIA ED A GIA EDA HG+ANE AAHG+ANEDA H IA  D+ + IANE 
Sbjct: 183 GIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242

Query: 569 ATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIA 628
           A   IA + V   +      H  AN   VH +A ED+V  +ANE AV+ +AN+     + 
Sbjct: 243 AIYDIANDTVQGTLTR--TLH--ANVDTVHDIANEDSVYDIANEGAVYDIANDTVQGTLT 298

Query: 629 KEVTAHGVANEDAVQGVVN------------EDALHGVVANEDAAQAIAKPDAAHGIANE 676
           + +    +        V+             + +L   +       A  K      +   
Sbjct: 299 RTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALYTT 358

Query: 677 V----AAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQG 717
           +      H I   DA   IANED+   IANE A + I+  D VQG
Sbjct: 359 LLMIPTRHAIV--DAVHDIANEDSVYDIANEGAVYDIA-NDTVQG 400



 Score =  185 bits (469), Expect = 5e-46
 Identities = 128/318 (40%), Positives = 159/318 (50%), Gaps = 47/318 (14%)

Query: 1176 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAA---HGVANEDAAHAIAKPDAARGIANEVA 1232
            E + + + H+D   G   E  V+    +VA        +ED  H I   DA+  I NE A
Sbjct: 88   EASEESLVHKDRGDG---ERPVNVKVVQVAPLRRESTPHEDTVHNITNEDASHDITNEDA 144

Query: 1233 AQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIAN 1292
              GIA E    GIANEDAA G+ANE AAHGI+ EDA QGIANE AAQGIA EDA QGIA 
Sbjct: 145  VHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQGIANEDAAQGIAK 204

Query: 1293 EDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANE-------------- 1338
            EDAA GIA ED   G+ANED + G+ANE  V  +A+EDA+  IAN+              
Sbjct: 205  EDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIANDTVQGTLTRTLHANV 264

Query: 1339 DAAHGIANEDAAQGIANEDAAQDIANEDAAQGI--------------SKEDAVQGIANED 1384
            D  H IANED+   IANE A  DIAN D  QG                K   ++ +    
Sbjct: 265  DTVHDIANEDSVYDIANEGAVYDIAN-DTVQGTLTRTLYTTSLMRTPYKASVMRTLYTTS 323

Query: 1385 AAQGIAKEDPVQGVANEDAVQGVANEVEVQGV-----------AHEDAVQGIANEDAAHG 1433
              +   K    + +     +        ++ +           A  DAV  IANED+ + 
Sbjct: 324  LTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALYTTLLMIPTRHAIVDAVHDIANEDSVYD 383

Query: 1434 IANEVAAHGIANEDAAQG 1451
            IANE A + IAN D  QG
Sbjct: 384  IANEGAVYDIAN-DTVQG 400



 Score =  185 bits (469), Expect = 5e-46
 Identities = 116/289 (40%), Positives = 148/289 (51%), Gaps = 27/289 (9%)

Query: 693 NEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAH 752
           +ED    I NE A+H I+ EDAV GIANE A +GIA+EDA QGIANEDA         AH
Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDA---------AH 173

Query: 753 GVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANED 812
           G+A+ED  QG+ANE   QG+ANE   QGIA EDA  GIANEDAAHGIANE A HG+ANED
Sbjct: 174 GIASEDAAQGIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANED 233

Query: 813 AAQGVANEDAAQGVANE--------------DAVHGVANEDAAQGVAKEVTAHGVTNEDA 858
           +   +ANEDA   +AN+              D VH +ANED+   +A E   + + N D 
Sbjct: 234 SVYDIANEDAIYDIANDTVQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYDIAN-DT 292

Query: 859 VQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAA 918
           VQG +        +       ++ +      +        +      T  +         
Sbjct: 293 VQGTLTRTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPM 352

Query: 919 HGI--TKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQG 965
             +  T        A  DA H I NED+   +ANE A + +AN D  QG
Sbjct: 353 RALYTTLLMIPTRHAIVDAVHDIANEDSVYDIANEGAVYDIAN-DTVQG 400



 Score =  184 bits (466), Expect = 1e-45
 Identities = 124/329 (37%), Positives = 167/329 (50%), Gaps = 32/329 (9%)

Query: 450 EDAAQGIAHEDAAQGIAHEDA----VQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPD 505
           E + + + H+D   G    +     V  +  E   H    E   H + N+DA+H I   D
Sbjct: 88  EASEESLVHKDRGDGERPVNVKVVQVAPLRRESTPH----EDTVHNITNEDASHDITNED 143

Query: 506 AARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIA 565
           A  GIANE A +GIA ED A GIANEDA HG+A+E AA G+ANE AA          GIA
Sbjct: 144 AVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQ---------GIA 194

Query: 566 NEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQ 625
           NE A QGIA ED A GIANEDAAHG+ANE AVHG+A ED+V  +ANEDA++ +AN D  Q
Sbjct: 195 NEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIAN-DTVQ 253

Query: 626 GI------AKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAA 679
           G       A   T H +ANED+V  + NE A++  +AN+     + +      +      
Sbjct: 254 GTLTRTLHANVDTVHDIANEDSVYDIANEGAVYD-IANDTVQGTLTRTLYTTSLMRTPYK 312

Query: 680 HGIANEDAAQGIANEDAAQGIANEVAAHGIS----KEDAVQGIANEDAAQGIAHE--DAV 733
             +        +        +   +    +     K   ++ +          H   DAV
Sbjct: 313 ASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALYTTLLMIPTRHAIVDAV 372

Query: 734 QGIANEDAVHGVAKEVAAHGVANEDPVQG 762
             IANED+V+ +A E A + +AN D VQG
Sbjct: 373 HDIANEDSVYDIANEGAVYDIAN-DTVQG 400



 Score =  182 bits (461), Expect = 4e-45
 Identities = 116/283 (40%), Positives = 147/283 (51%), Gaps = 23/283 (8%)

Query: 1770 NEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAH 1829
            +ED VH++  E A+H + NEDA H IA   A +GIANE AAQGIA ED A GI +EDAA 
Sbjct: 123  HEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQ 182

Query: 1830 GVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANED 1889
            G+ANEVAA GI+ EDA QGIA EDAA GIA ED   G+ANE  V G+A+ED+V  IANED
Sbjct: 183  GIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242

Query: 1890 AAHGIANEDAAQGI------ANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKED 1943
            A + IAN D  QG       AN D   DIANED+   I+ E AV  IAN      + +  
Sbjct: 243  AIYDIAN-DTVQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYDIANDTVQGTLTRTL 301

Query: 1944 AVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIA----HEDAVQGI------ 1993
                +        +   +    +        +        +         ++ +      
Sbjct: 302  YTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALYTTLLM 361

Query: 1994 -----ANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIAT 2031
                 A  DAVH +ANED+ + IA   A   IAN+   QG  T
Sbjct: 362  IPTRHAIVDAVHDIANEDSVYDIANEGAVYDIAND-TVQGTLT 403



 Score =  175 bits (443), Expect = 5e-43
 Identities = 101/178 (56%), Positives = 118/178 (66%), Gaps = 6/178 (3%)

Query: 1554 EDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAH 1613
            ED V  +  E  +H + NEDAV G+ NE A    +ANEDAAQ IA  DAAHGIA+E AA 
Sbjct: 124  EDTVHNITNEDASHDITNEDAVHGIANE-AADKGIANEDAAQGIANEDAAHGIASEDAAQ 182

Query: 1614 SIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHED 1673
             IAN+ AAQGIAN+DAAQGIA E AAHGI+ EDA  GIANEDA  GIANED+   IA+ED
Sbjct: 183  GIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242

Query: 1674 AVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQG 1731
            A+  IAN D V G          AN D V  +ANED+V  +ANE  V  +A+ D VQG
Sbjct: 243  AIYDIAN-DTVQGTLTRTLH---ANVDTVHDIANEDSVYDIANEGAVYDIAN-DTVQG 295



 Score =  174 bits (442), Expect = 7e-43
 Identities = 116/308 (37%), Positives = 153/308 (49%), Gaps = 48/308 (15%)

Query: 761  QGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANE 820
            +   +ED V  + NE     I +EDAV GIANE A  GIANE AA G+ANEDAA G+A+E
Sbjct: 119  ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASE 178

Query: 821  DAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQA 880
            DAAQG+ANE A  G+ANEDAAQG+AKE  AHG+ NEDA  G+ NE+A+HG +ANED+   
Sbjct: 179  DAAQGIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHG-IANEDSVYD 237

Query: 881  IAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSIT 940
            IA  DA + IAN+ V      QG  T  +                     A  D  H I 
Sbjct: 238  IANEDAIYDIANDTV------QGTLTRTLH--------------------ANVDTVHDIA 271

Query: 941  NEDAAQGVANEDAAHGVANEDAAQGVAN-------------EVAAQGVANEDAVHGVANE 987
            NED+   +ANE A + +AN D  QG                + +        ++     +
Sbjct: 272  NEDSVYDIANEGAVYDIAN-DTVQGTLTRTLYTTSLMRTPYKASVMRTLYTTSLTRTPYK 330

Query: 988  DAVQGVANEVEVQGIAHKDA-----IQGIANEDAAHGIANEVAAHGIANEDAAQGIANED 1042
             ++        +    +K +        +      H I +  A H IANED+   IANE 
Sbjct: 331  PSLTRTLYTTSLMMAPYKTSPMRALYTTLLMIPTRHAIVD--AVHDIANEDSVYDIANEG 388

Query: 1043 AAQGIANE 1050
            A   IAN+
Sbjct: 389  AVYDIAND 396



 Score =  170 bits (431), Expect = 1e-41
 Identities = 125/326 (38%), Positives = 157/326 (48%), Gaps = 35/326 (10%)

Query: 1455 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQG 1514
            E + + + H+D   G   E  V+    +VA   +  E   H     D    I NE A+  
Sbjct: 88   EASEESLVHKDRGDG---ERPVNVKVVQVAP--LRRESTPHE----DTVHNITNEDASHD 138

Query: 1515 IATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDA 1574
            I  ED   GIANE A  G+ANE AAQGIANE A HG+A EDA QG+  EV A G+ANEDA
Sbjct: 139  ITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQGIANEDA 198

Query: 1575 VQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGI- 1633
             QG+  EDA H  +ANEDAA  IA  DA HGIANE + + IAN+DA   IAN D  QG  
Sbjct: 199  AQGIAKEDAAHG-IANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIAN-DTVQGTL 256

Query: 1634 -----ANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIA--------------HEDA 1674
                 AN    H I+ ED+V  IANE A   IAN D  QG                    
Sbjct: 257  TRTLHANVDTVHDIANEDSVYDIANEGAVYDIAN-DTVQGTLTRTLYTTSLMRTPYKASV 315

Query: 1675 VQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHE--DAVQGI 1732
            ++ +          K      +     +        ++ +   + +    H   DAV  I
Sbjct: 316  MRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALYTTLLMIPTRHAIVDAVHDI 375

Query: 1733 ANEDAAHGITNEVAAHGIANEDAAQG 1758
            ANED+ + I NE A + IAN D  QG
Sbjct: 376  ANEDSVYDIANEGAVYDIAN-DTVQG 400



 Score = 32.7 bits (73), Expect = 4.4
 Identities = 15/34 (44%), Positives = 21/34 (61%), Gaps = 1/34 (2%)

Query: 830 DAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVV 863
           DAVH +ANED+   +A E   + + N D VQG +
Sbjct: 370 DAVHDIANEDSVYDIANEGAVYDIAN-DTVQGTL 402


>gi|239746623 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 445

 Score =  359 bits (921), Expect = 2e-98
 Identities = 201/341 (58%), Positives = 224/341 (65%), Gaps = 62/341 (18%)

Query: 2081 EDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHG 2140
            ED V  ITNE         DA+H IT EDA  G+ NE AAQG+ANEDAA G+ANE AAHG
Sbjct: 124  EDTVHNITNE---------DASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHG 174

Query: 2141 VANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVA 2200
            +A+EDAAQG+ANEVAAQG+ANEDA QG+ANE         DA+ GIANEDAA G+ANE A
Sbjct: 175  IASEDAAQGIANEVAAQGIANEDAAQGIANE---------DAVHGIANEDAAHGIANEDA 225

Query: 2201 AHGVANEDAAQGVANEVAAQGVANEDAAQGVANEV--------------AVHGVANEDAA 2246
             HG+ANED+   +ANE A   +AN D  QG    +               +  +      
Sbjct: 226  VHGIANEDSVYDIANEDAIYDIAN-DTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLT 284

Query: 2247 RHMAKEDAAQGI-----------------------------ANEDAAHGIANEDAVHGIA 2277
            R + K    + +                             AN D  H IANED+V+ IA
Sbjct: 285  RTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIA 344

Query: 2278 NEDAVYDIANDTVQGTLTRTLYRTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTT 2337
            NE AVYDIANDTVQGTLTRTLY TSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTT
Sbjct: 345  NEGAVYDIANDTVQGTLTRTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTT 404

Query: 2338 SLMRAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDTV 2378
            SLM APYKTSPMRALYTTLLMIPTRHAN D VHDIANEDTV
Sbjct: 405  SLMTAPYKTSPMRALYTTLLMIPTRHANVDAVHDIANEDTV 445



 Score =  347 bits (891), Expect = 6e-95
 Identities = 180/236 (76%), Positives = 196/236 (83%), Gaps = 18/236 (7%)

Query: 2143 NEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAH 2202
            +ED    + NE A+  + NEDAV G+ANE          A QGIANEDAAQG+ANE AAH
Sbjct: 123  HEDTVHNITNEDASHDITNEDAVHGIANEA---------AAQGIANEDAAQGIANEDAAH 173

Query: 2203 GVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANED 2262
            G+A+EDAAQG+ANEVAAQG+ANEDAAQG+ANE AVHG+AN         EDAA GIANED
Sbjct: 174  GIASEDAAQGIANEVAAQGIANEDAAQGIANEDAVHGIAN---------EDAAHGIANED 224

Query: 2263 AAHGIANEDAVHGIANEDAVYDIANDTVQGTLTRTLYRTSLMRTPYKASVMRTLYTTSLT 2322
            A HGIANED+V+ IANEDA+YDIANDTVQGTLTR LY TSLMRTPYKASVMRTLY TSLT
Sbjct: 225  AVHGIANEDSVYDIANEDAIYDIANDTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLT 284

Query: 2323 RTPYKPSLTRTLYTTSLMRAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDTV 2378
            RT YKPSLTRTLYTTSLM APYKTSPMRALYTTLLMIPTRHANADTVHDIANED+V
Sbjct: 285  RTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSV 340



 Score =  270 bits (691), Expect = 1e-71
 Identities = 151/274 (55%), Positives = 179/274 (65%), Gaps = 36/274 (13%)

Query: 16  SSEESLVHKDRGDGERPVNVRVVQVAPLRHESTPYEDTVHDIANEDADAAHGITNEDAVQ 75
           +SEESLVHKDRGDGERPVNVRVVQVAPLR ESTP+EDTVH+I NEDA  +H ITNEDAV 
Sbjct: 89  ASEESLVHKDRGDGERPVNVRVVQVAPLRRESTPHEDTVHNITNEDA--SHDITNEDAVH 146

Query: 76  GVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANED 135
           G+ANE AAQG+ANEDAA G+ANE AAHG+A+EDAAQG+ANEVAAQG+ANEDA QG+ANED
Sbjct: 147 GIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQGIANEDAAQGIANED 206

Query: 136 AVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIA------------------ 177
           AV G+ANEDA  GIANEDA HGIANED+   IANEDA  DIA                  
Sbjct: 207 AVHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIANDTVQGTLTRMLYTTSLM 266

Query: 178 ----KEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGV-----------A 222
               K    + +      + + K    + +          K  P++ +           A
Sbjct: 267 RTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHA 326

Query: 223 NEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQG 256
           N D V  +ANED+V  +ANE  V  +A+ D VQG
Sbjct: 327 NADTVHDIANEDSVYDIANEGAVYDIAN-DTVQG 359



 Score =  191 bits (485), Expect = 7e-48
 Identities = 97/133 (72%), Positives = 108/133 (81%), Gaps = 1/133 (0%)

Query: 1004 HKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQ 1063
            H+D +  I NEDA+H I NE A HGIANE AAQGIANEDAAQGIANE AAHGI+ EDA Q
Sbjct: 123  HEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQ 182

Query: 1064 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANED 1123
            GIANE AAQGIANEDAAQGIA+EDAV GIANEDA HG+A E A HG+ANED V  +ANED
Sbjct: 183  GIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242

Query: 1124 AVQGVANEVEVQG 1136
            A+  +AN+  VQG
Sbjct: 243  AIYDIANDT-VQG 254



 Score =  191 bits (484), Expect = 1e-47
 Identities = 121/254 (47%), Positives = 141/254 (55%), Gaps = 27/254 (10%)

Query: 1324 QGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANE 1383
            +   HED V  I NEDA+H I NEDA  GIANE AAQ IANEDAAQGI+ EDA  GIA+E
Sbjct: 119  ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASE 178

Query: 1384 DAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGI 1443
            DAAQGIA E   QG+ANEDA QG+ANE         DAV GIANEDAAHGIANE A HGI
Sbjct: 179  DAAQGIANEVAAQGIANEDAAQGIANE---------DAVHGIANEDAAHGIANEDAVHGI 229

Query: 1444 ANEDAAQGIANEDAAQGIAHEDAVQG-----IANEDAVHGVAKEVAAHGVANEDAAHAIA 1498
            ANED+   IANEDA   IA+ D VQG     +     +    K      +        + 
Sbjct: 230  ANEDSVYDIANEDAIYDIAN-DTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLY 288

Query: 1499 KPDAARGI-ANEVATQGIATED----------VADGIANEDAAHGVANEVAAQGIANEVA 1547
            KP   R +    + T    T            +    AN D  H +ANE +   IANE A
Sbjct: 289  KPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGA 348

Query: 1548 VHGVAIEDAVQGVV 1561
            V+ +A  D VQG +
Sbjct: 349  VYDIA-NDTVQGTL 361



 Score =  189 bits (481), Expect = 2e-47
 Identities = 112/239 (46%), Positives = 133/239 (55%), Gaps = 42/239 (17%)

Query: 1874 QGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQ 1933
            +   HED V  I NEDA+H I NEDA  GIANE AAQ IANEDAAQGI+ EDA  GIA++
Sbjct: 119  ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASE 178

Query: 1934 DAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGI 1993
            DAAQGIA E A QGIANEDAAQGIANE A HGIANEDAA GIANEDA  GIA+ED+V  I
Sbjct: 179  DAAQGIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDI 238

Query: 1994 ANEDAVHGVANE-------------------------------DAAHAIAKPDAARGI-- 2020
            ANEDA++ +AN+                                    + KP   R +  
Sbjct: 239  ANEDAIYDIANDTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYT 298

Query: 2021 ---------ANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGI 2070
                      + + A       +    AN D  H +ANED+   IA   A + IAN+ +
Sbjct: 299  TSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIANDTV 357



 Score =  189 bits (480), Expect = 3e-47
 Identities = 111/242 (45%), Positives = 143/242 (59%), Gaps = 8/242 (3%)

Query: 933  QDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQG 992
            +D  H+ITNEDA+  + NEDA HG+ANE AAQG+ANE AAQG+ANEDA HG+A+EDA QG
Sbjct: 124  EDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQG 183

Query: 993  VANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVA 1052
            +ANEV  QGIA++DA QGIANEDA HGIANE AAHGIANEDA  GIANED+   IANE A
Sbjct: 184  IANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDA 243

Query: 1053 AHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVAN 1112
             + I+  D VQG       + +      +       ++ +        + K      +  
Sbjct: 244  IYDIA-NDTVQG----TLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYT 298

Query: 1113 EDPVQGVANEDAVQGVANEVEVQGVAH--EDAVQGIANEDAAHGIANEVAAHGIANEDAA 1170
               +        ++ +   + +    H   D V  IANED+ + IANE A + IAN D  
Sbjct: 299  TSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIAN-DTV 357

Query: 1171 QG 1172
            QG
Sbjct: 358  QG 359



 Score =  179 bits (455), Expect = 2e-44
 Identities = 110/238 (46%), Positives = 133/238 (55%), Gaps = 18/238 (7%)

Query: 1059 EDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQG 1118
            ED V  I NEDA+  I NEDA  GIA+E A QGIANEDA  G+A E AAHG+A+ED  QG
Sbjct: 124  EDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQG 183

Query: 1119 VANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDA 1178
            +ANE A QG+ANE   QG+A+EDAV GIANEDAAHGIANE A HGIANED+   IANEDA
Sbjct: 184  IANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDA 243

Query: 1179 AQGIAHEDAVQG-----IANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGI------ 1227
               IA+ D VQG     +     +    K      +        + KP   R +      
Sbjct: 244  IYDIAN-DTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSLM 302

Query: 1228 -----ANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQG 1280
                  + + A       +    AN D  H +ANE + + I+ E AV  IAN D  QG
Sbjct: 303  TAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIAN-DTVQG 359



 Score =  179 bits (453), Expect = 4e-44
 Identities = 114/246 (46%), Positives = 140/246 (56%), Gaps = 13/246 (5%)

Query: 385 NEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAV 444
           +ED +H +  NEDA+  I   DA HGIANE AA GIANEDAAQGIANE AAHGI+ EDA 
Sbjct: 123 HEDTVHNIT-NEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAA 181

Query: 445 QGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKP 504
           QGIANE AAQGIA+EDAAQGIA+EDAV GIANEDA HG+A E A HG+AN+D+ + IA  
Sbjct: 182 QGIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANE 241

Query: 505 DAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGI 564
           DA   IAN+   QG  T      +     +           +        + KP     +
Sbjct: 242 DAIYDIAND-TVQGTLTR----MLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTL 296

Query: 565 -ANEVATQGIATEDVA---DGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVAN 620
               + T    T  +      +      H  AN   VH +A ED+V  +ANE AV+ +AN
Sbjct: 297 YTTSLMTAPYKTSPMRALYTTLLMIPTRH--ANADTVHDIANEDSVYDIANEGAVYDIAN 354

Query: 621 EDAAQG 626
            D  QG
Sbjct: 355 -DTVQG 359



 Score =  179 bits (453), Expect = 4e-44
 Identities = 109/238 (45%), Positives = 133/238 (55%), Gaps = 27/238 (11%)

Query: 1239 EDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQG 1298
            ED    I NEDA+H + NE A HGI+ E A QGIANEDAAQGIA EDA  GIA+EDAAQG
Sbjct: 124  EDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQG 183

Query: 1299 IAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDA 1358
            IA E   QG+ANED  QG+ANE  V G+A+EDA  GIANEDA HGIANED+   IANEDA
Sbjct: 184  IANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDA 243

Query: 1359 AQDIANEDAAQGI--------------SKEDAVQGIANEDAAQGIAKEDPVQGVANEDAV 1404
              DIAN D  QG                K   ++ +      + + K    + +     +
Sbjct: 244  IYDIAN-DTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSLM 302

Query: 1405 QGVANEVEVQGV-----------AHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQG 1451
                    ++ +           A+ D V  IANED+ + IANE A + IAN D  QG
Sbjct: 303  TAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIAN-DTVQG 359



 Score =  179 bits (453), Expect = 4e-44
 Identities = 105/233 (45%), Positives = 128/233 (54%), Gaps = 26/233 (11%)

Query: 179 EDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQG 238
           ED   +I NEDA+  I+ EDAV GIANE AAQGIA ED  QG+ANED   G+A+EDA QG
Sbjct: 124 EDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQG 183

Query: 239 VANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDA 298
           +ANEV  QG+A+EDA QGIANEDA HGI NE AAHGIANEDA  GIANED+   IA+EDA
Sbjct: 184 IANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDA 243

Query: 299 VQGIANEDAVHGVA--------------KEVAAHGVANEDAAHAIAKPDAAHGI-ANEVA 343
           +  IAN D V G                K      +        + KP     +    + 
Sbjct: 244 IYDIAN-DTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSLM 302

Query: 344 TQGIATED----------VADGIANEDAAHGVAKEVTAHGVANEDAVQGVVNE 386
           T    T            +    AN D  H +A E + + +ANE AV  + N+
Sbjct: 303 TAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIAND 355



 Score =  178 bits (452), Expect = 5e-44
 Identities = 92/133 (69%), Positives = 104/133 (78%), Gaps = 1/133 (0%)

Query: 1590 NEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQ 1649
            +ED    I   DA+H I NE A H IAN+ AAQGIAN+DAAQGIANE AAHGI+ EDA Q
Sbjct: 123  HEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQ 182

Query: 1650 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANED 1709
            GIANE AAQGIANEDAAQGIA+EDAV GIANEDA HG+A E A HG+ANED V  +ANED
Sbjct: 183  GIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242

Query: 1710 AVQGVANEVEVQG 1722
            A+  +AN+  VQG
Sbjct: 243  AIYDIANDT-VQG 254



 Score =  177 bits (448), Expect = 1e-43
 Identities = 93/133 (69%), Positives = 103/133 (77%), Gaps = 1/133 (0%)

Query: 657 NEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQ 716
           +ED    I   DA+H I NE A HGIANE AAQGIANEDAAQGIANE AAHGI+ EDA Q
Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQ 182

Query: 717 GIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEV 776
           GIANE AAQGIA+EDA QGIANEDAVHG+A E AAHG+ANED V G+ANED V  +ANE 
Sbjct: 183 GIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242

Query: 777 EVQGIAHEDAVQG 789
            +  IA+ D VQG
Sbjct: 243 AIYDIAN-DTVQG 254



 Score =  177 bits (448), Expect = 1e-43
 Identities = 104/254 (40%), Positives = 135/254 (53%), Gaps = 18/254 (7%)

Query: 712 EDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQG 771
           ED V  I NEDA+  I +EDAV GIANE A  G+A E AA G+ANED   G+A+ED  QG
Sbjct: 124 EDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQG 183

Query: 772 VANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDA 831
           +ANEV  QGIA+EDA QGIANEDA HGIANE AAHG+ANEDA  G+ANED+   +ANEDA
Sbjct: 184 IANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDA 243

Query: 832 VHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIA 891
           ++ +AN D  QG     T   +    ++     + ++   +      + + KP     + 
Sbjct: 244 IYDIAN-DTVQG-----TLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLY 297

Query: 892 NEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANE 951
              +                 +     H           A  D  H I NED+   +ANE
Sbjct: 298 TTSLMTAPYKTSPMRALYTTLLMIPTRH-----------ANADTVHDIANEDSVYDIANE 346

Query: 952 DAAHGVANEDAAQG 965
            A + +AN D  QG
Sbjct: 347 GAVYDIAN-DTVQG 359



 Score =  176 bits (446), Expect = 2e-43
 Identities = 108/243 (44%), Positives = 130/243 (53%), Gaps = 44/243 (18%)

Query: 246 QGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANE 305
           +   HED V  I NEDA+H ITNE A HGIANE AAQGIANEDAAQGIA+EDA  GIA+E
Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASE 178

Query: 306 DAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGV 365
           DA  G+A EVAA G+ANEDAA  IA  DA HGIANE A  GIA ED   GIANED+ + +
Sbjct: 179 DAAQGIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDI 238

Query: 366 AKEVTAHGVANEDAVQGVVN-------------EDALHGVVANEDAAQAIAKPDAAHGI- 411
           A E   + +AN D VQG +              + ++   +      + + KP     + 
Sbjct: 239 ANEDAIYDIAN-DTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLY 297

Query: 412 ----------------------------ANEVAAHGIANEDAAQGIANEVAAHGISKEDA 443
                                       AN    H IANED+   IANE A + I+  D 
Sbjct: 298 TTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIA-NDT 356

Query: 444 VQG 446
           VQG
Sbjct: 357 VQG 359



 Score =  176 bits (446), Expect = 2e-43
 Identities = 104/237 (43%), Positives = 130/237 (54%), Gaps = 16/237 (6%)

Query: 1104 EVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHG 1163
            E   H + NED    + NEDAV G+ANE   QG+A+EDA QGIANEDAAHGIA+E AA G
Sbjct: 124  EDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQG 183

Query: 1164 IANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDA 1223
            IANE AAQGIANEDAAQGIA+EDAV GIANEDA HG+A E A HG+ANED+ + IA  DA
Sbjct: 184  IANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDA 243

Query: 1224 ARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGIS----KEDAVQGIANEDAAQ 1279
               IAN+     +        +        V   +    ++    K    + +       
Sbjct: 244  IYDIANDTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSLMT 303

Query: 1280 GIAKEDAVQGI-----------ANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQG 1325
               K   ++ +           AN D    IA ED V  +ANE  +  +AN+  VQG
Sbjct: 304  APYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIANDT-VQG 359



 Score =  176 bits (445), Expect = 3e-43
 Identities = 108/273 (39%), Positives = 140/273 (51%), Gaps = 25/273 (9%)

Query: 1609 EVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQG 1668
            E +  S+ +KD   G    +        +       ED V  I NEDA+  I NEDA  G
Sbjct: 88   EASEESLVHKDRGDGERPVNVRVVQVAPLRRESTPHEDTVHNITNEDASHDITNEDAVHG 147

Query: 1669 IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDA 1728
            IA+E A QGIANEDA  G+A E AAHG+A+ED  QG+ANE A QG+ANE   QG+A+EDA
Sbjct: 148  IANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQGIANEDAAQGIANEDA 207

Query: 1729 VQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVAN 1788
            V GIANEDAAHGI NE A HGIANED+   IA+EDA+  IAN+    ++ + +    +  
Sbjct: 208  VHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIANDTVQGTLTRMLYTTSLMR 267

Query: 1789 -------------EDAAHAIAKPDAARGI-----------ANEVAAQGIATEDVADGIPN 1824
                               + KP   R +            + + A       +     N
Sbjct: 268  TPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHAN 327

Query: 1825 EDAAHGVANEVAAHGISKEDAVQGIANEDAAQG 1857
             D  H +ANE + + I+ E AV  IAN D  QG
Sbjct: 328  ADTVHDIANEDSVYDIANEGAVYDIAN-DTVQG 359



 Score =  176 bits (445), Expect = 3e-43
 Identities = 113/256 (44%), Positives = 134/256 (52%), Gaps = 35/256 (13%)

Query: 1721 QGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKE 1780
            +   HED V  I NEDA+H ITNE A HGIANE AA         QGIANEDA       
Sbjct: 119  ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAAA---------QGIANEDA------- 162

Query: 1781 VAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGI 1840
              A G+ANEDAAH IA  DAA+GIANEVAAQGIA ED A GI NEDA HG+ANE AAHGI
Sbjct: 163  --AQGIANEDAAHGIASEDAAQGIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGI 220

Query: 1841 SKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHE-----DAVQGIANEDAAHGIA 1895
            + EDAV GIANED+   IA ED I  +AN+  VQG           ++          + 
Sbjct: 221  ANEDAVHGIANEDSVYDIANEDAIYDIANDT-VQGTLTRMLYTTSLMRTPYKASVMRTLY 279

Query: 1896 NEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGI-----------ANQDAAQGIAKEDA 1944
                 + +      + +          K   ++ +           AN D    IA ED+
Sbjct: 280  MTSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDS 339

Query: 1945 VQGIANEDAAQGIANE 1960
            V  IANE A   IAN+
Sbjct: 340  VYDIANEGAVYDIAND 355



 Score =  175 bits (444), Expect = 4e-43
 Identities = 113/276 (40%), Positives = 147/276 (53%), Gaps = 22/276 (7%)

Query: 1077 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAA---HGVANEDPVQGVANEDAVQGVANEVE 1133
            E + + + H+D   G   E  V+    +VA        +ED V  + NEDA   + NE  
Sbjct: 88   EASEESLVHKDRGDG---ERPVNVRVVQVAPLRRESTPHEDTVHNITNEDASHDITNEDA 144

Query: 1134 VQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIAN 1193
            V G+A+E A QGIANEDAA GIANE AAHGIA+EDAAQGIANE AAQGIA+EDA QGIAN
Sbjct: 145  VHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQGIANEDAAQGIAN 204

Query: 1194 EDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHG 1253
            EDAVHG+A E AAHG+ANEDA H IA  D+   IANE A   IA + V   +        
Sbjct: 205  EDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIANDTVQGTLTRM----- 259

Query: 1254 VANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGV----- 1308
            +          K   ++ +      + + K    + +          K  P++ +     
Sbjct: 260  LYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLL 319

Query: 1309 ------ANEDPIQGVANEVEVQGVAHEDAVQGIANE 1338
                  AN D +  +ANE  V  +A+E AV  IAN+
Sbjct: 320  MIPTRHANADTVHDIANEDSVYDIANEGAVYDIAND 355



 Score =  175 bits (444), Expect = 4e-43
 Identities = 106/245 (43%), Positives = 135/245 (55%), Gaps = 12/245 (4%)

Query: 607 QGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAK 666
           +   +ED VH + NEDA+  I  E   HG+ANE A QG+ NEDA  G +ANEDAA  IA 
Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQG-IANEDAAHGIAS 177

Query: 667 PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG 726
            DAA GIANEVAA GIANEDAAQGIANEDA  GIANE AAHGI+ EDAV GIANED+   
Sbjct: 178 EDAAQGIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYD 237

Query: 727 IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDA 786
           IA+EDA+  IAN+     + + +    +        V     +  +   +    +     
Sbjct: 238 IANEDAIYDIANDTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLY 297

Query: 787 VQGIANEDAAHGIANEVAAHGV--------ANEDAAQGVANEDAAQGVANEDAVHGVANE 838
              +    A +  +   A +          AN D    +ANED+   +ANE AV+ +AN 
Sbjct: 298 TTSLMT--APYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIAN- 354

Query: 839 DAAQG 843
           D  QG
Sbjct: 355 DTVQG 359



 Score =  175 bits (443), Expect = 5e-43
 Identities = 104/239 (43%), Positives = 129/239 (53%), Gaps = 15/239 (6%)

Query: 129 QGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANE 188
           +   +ED V  + NEDA   I NEDA HGIANE AAQGIANEDAAQ IA EDAA  IA+E
Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASE 178

Query: 189 DAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGV 248
           DAAQGI+ E A QGIANEDAAQGIA ED V G+ANED   G+ANEDAV G+ANE  V  +
Sbjct: 179 DAAQGIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDI 238

Query: 249 AHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAN----EDAAQGIAHEDAVQGIAN 304
           A+EDA+  IAN+     +T  +    +        +          + +      + +  
Sbjct: 239 ANEDAIYDIANDTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYT 298

Query: 305 EDAVHGVAKEVAAHGV-----------ANEDAAHAIAKPDAAHGIANEVATQGIATEDV 352
              +    K      +           AN D  H IA  D+ + IANE A   IA + V
Sbjct: 299 TSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIANDTV 357



 Score =  175 bits (443), Expect = 5e-43
 Identities = 102/237 (43%), Positives = 135/237 (56%), Gaps = 16/237 (6%)

Query: 924  EEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHG 983
            E+    I  +DA+H ITNEDA  G+ANE AA G+ANEDAAQG+ANE AA G+A+EDA  G
Sbjct: 124  EDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQG 183

Query: 984  VANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDA 1043
            +ANE A QG+ANE   QGIA++DA+ GIANEDAAHGIANE A HGIANED+   IANEDA
Sbjct: 184  IANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDA 243

Query: 1044 AQGIANEVAAHGISK----EDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVH 1099
               IAN+     +++       ++        + +      + +      + +     + 
Sbjct: 244  IYDIANDTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSLMT 303

Query: 1100 GVAKEVAAHGV-----------ANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQG 1145
               K      +           AN D V  +ANED+V  +ANE  V  +A+ D VQG
Sbjct: 304  APYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIAN-DTVQG 359



 Score =  174 bits (441), Expect = 9e-43
 Identities = 98/179 (54%), Positives = 118/179 (65%), Gaps = 10/179 (5%)

Query: 940  TNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEV 999
            T E + + + ++D   G    +        +  +   +ED VH + NEDA   + NE   
Sbjct: 86   TLEASEESLVHKDRGDGERPVNVRVVQVAPLRRESTPHEDTVHNITNEDASHDITNE--- 142

Query: 1000 QGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKE 1059
                  DA+ GIANE AA GIANE AA GIANEDAA GIA+EDAAQGIANEVAA GI+ E
Sbjct: 143  ------DAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQGIANE 196

Query: 1060 DAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQG 1118
            DA QGIANEDA  GIANEDAA GIA+EDAV GIANED+V+ +A E A + +AN D VQG
Sbjct: 197  DAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIAN-DTVQG 254



 Score =  172 bits (436), Expect = 4e-42
 Identities = 106/234 (45%), Positives = 127/234 (54%), Gaps = 44/234 (18%)

Query: 1166 NEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAR 1225
            +ED    I NEDA+  I +EDAV GIANE A  G+A E AA G+ANEDAAH IA  DAA+
Sbjct: 123  HEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQ 182

Query: 1226 GIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKED 1285
            GIANEVAAQGIA ED A GIANEDA HG+ANE AAHGI+ EDAV GIANED+   IA ED
Sbjct: 183  GIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242

Query: 1286 AVQGIANEDAAQG-----------------------------------------IAKEDP 1304
            A+  IAN D  QG                                         +     
Sbjct: 243  AIYDIAN-DTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSL 301

Query: 1305 VQGVANEDPIQGVANEVEVQGVAHEDA--VQGIANEDAAHGIANEDAAQGIANE 1356
            +       P++ +   + +    H +A  V  IANED+ + IANE A   IAN+
Sbjct: 302  MTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIAND 355



 Score =  172 bits (435), Expect = 5e-42
 Identities = 90/137 (65%), Positives = 103/137 (75%), Gaps = 1/137 (0%)

Query: 991  QGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANE 1050
            +   +E  V  I ++DA   I NEDA HGIANE AA GIANEDAAQGIANEDAA GIA+E
Sbjct: 119  ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASE 178

Query: 1051 VAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGV 1110
             AA GI+ E A QGIANEDAAQGIANEDA  GIA+EDA  GIANEDAVHG+A E + + +
Sbjct: 179  DAAQGIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDI 238

Query: 1111 ANEDPVQGVANEDAVQG 1127
            ANED +  +AN D VQG
Sbjct: 239  ANEDAIYDIAN-DTVQG 254



 Score =  171 bits (432), Expect = 1e-41
 Identities = 113/260 (43%), Positives = 136/260 (52%), Gaps = 36/260 (13%)

Query: 1776 SVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEV 1835
            S   E   H + NEDA+H I   DA  GIANE AAQGIA         NEDAA G+ANE 
Sbjct: 120  STPHEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIA---------NEDAAQGIANED 170

Query: 1836 AAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIA 1895
            AAHGI+ EDA QGIANE AAQGIA ED  QG+ANE         DAV GIANEDAAHGIA
Sbjct: 171  AAHGIASEDAAQGIANEVAAQGIANEDAAQGIANE---------DAVHGIANEDAAHGIA 221

Query: 1896 NEDAAQGIANEDAAQDIANEDAAQGISKEDAVQG-----IANQDAAQGIAKEDAVQGIAN 1950
            NEDA  GIANED+  DIANEDA   I+  D VQG     +      +   K   ++ +  
Sbjct: 222  NEDAVHGIANEDSVYDIANEDAIYDIA-NDTVQGTLTRMLYTTSLMRTPYKASVMRTLYM 280

Query: 1951 EDAAQGIANEVAAHGIANEDAAQGIANEDAAQGI-----------AHEDAVQGIANEDAV 1999
                + +        +               + +           A+ D V  IANED+V
Sbjct: 281  TSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSV 340

Query: 2000 HGVANEDAAHAIAKPDAARG 2019
            + +ANE A + IA  D  +G
Sbjct: 341  YDIANEGAVYDIAN-DTVQG 359



 Score =  170 bits (431), Expect = 1e-41
 Identities = 100/239 (41%), Positives = 132/239 (55%), Gaps = 8/239 (3%)

Query: 530 NEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAH 589
           +ED VH + NE A+H + NEDA H IA   AA GIANE A QGIA ED A GIA+EDAA 
Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQ 182

Query: 590 GVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNED 649
           G+ANEVA  G+A EDA QG+ANEDAVHG+ANEDAA GIA E   HG+ANED+V  + NED
Sbjct: 183 GIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242

Query: 650 ALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGI 709
           A++  +AN+     + +      +        +        +        +   +    +
Sbjct: 243 AIYD-IANDTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSL 301

Query: 710 S----KEDAVQGIANEDAAQGIAH--EDAVQGIANEDAVHGVAKEVAAHGVANEDPVQG 762
                K   ++ +          H   D V  IANED+V+ +A E A + +AN D VQG
Sbjct: 302 MTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIAN-DTVQG 359



 Score =  169 bits (428), Expect = 3e-41
 Identities = 108/286 (37%), Positives = 144/286 (50%), Gaps = 28/286 (9%)

Query: 721 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAA---HGVANEDPVQGVANEDVVQGVANEVE 777
           E + + + H+D   G   E  V+    +VA        +ED V  + NED    + NE  
Sbjct: 88  EASEESLVHKDRGDG---ERPVNVRVVQVAPLRRESTPHEDTVHNITNEDASHDITNEDA 144

Query: 778 VQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVAN 837
           V GIA+E A QGIANEDAA GIANE AAHG+A+EDAAQG+ANE AAQG+ANEDA  G+AN
Sbjct: 145 VHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQGIANEDAAQGIAN 204

Query: 838 EDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVAN 897
           EDA          HG+ NEDA  G+ NE+A+HG +ANED+   IA  DA + IAN+ V  
Sbjct: 205 EDA---------VHGIANEDAAHGIANEDAVHG-IANEDSVYDIANEDAIYDIANDTVQG 254

Query: 898 EVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGV 957
            +      T  +           +      + + K     ++                 +
Sbjct: 255 TLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRAL 314

Query: 958 -----------ANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQG 992
                      AN D    +ANE +   +ANE AV+ +AN D VQG
Sbjct: 315 YTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIAN-DTVQG 359



 Score =  168 bits (425), Expect = 7e-41
 Identities = 106/252 (42%), Positives = 133/252 (52%), Gaps = 17/252 (6%)

Query: 1022 NEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQ 1081
            +E   H I NEDA+  I NEDA  GIANE AA GI+ EDA QGIANEDAA GIA+EDAAQ
Sbjct: 123  HEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQ 182

Query: 1082 GIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHED 1141
            GIA+E A QGIANEDA  G+A E A HG+ANED   G+ANEDAV G+AN         ED
Sbjct: 183  GIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIAN---------ED 233

Query: 1142 AVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVA 1201
            +V  IANEDA + IAN+     +        +        +     ++ +        + 
Sbjct: 234  SVYDIANEDAIYDIANDTVQGTLTRMLYTTSLMRTPYKASV-----MRTLYMTSLTRTLY 288

Query: 1202 KEVAAHGVANEDAAHAIAKPDAARGIANE--VAAQGIATEDVADGIANEDAAHGVANEVA 1259
            K      +       A  K    R +     +     A  D    IANED+ + +ANE A
Sbjct: 289  KPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGA 348

Query: 1260 AHGISKEDAVQG 1271
             + I+  D VQG
Sbjct: 349  VYDIA-NDTVQG 359



 Score =  168 bits (425), Expect = 7e-41
 Identities = 89/142 (62%), Positives = 101/142 (71%), Gaps = 10/142 (7%)

Query: 1247 NEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQ 1306
            +ED  H + NE A+H I+ EDAV GIANE AAQGIA         NEDAAQGIA ED   
Sbjct: 123  HEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIA---------NEDAAQGIANEDAAH 173

Query: 1307 GVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANED 1366
            G+A+ED  QG+ANEV  QG+A+EDA QGIANEDA HGIANEDAA GIANEDA   IANED
Sbjct: 174  GIASEDAAQGIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANED 233

Query: 1367 AAQGISKEDAVQGIANEDAAQG 1388
            +   I+ EDA+  IAN D  QG
Sbjct: 234  SVYDIANEDAIYDIAN-DTVQG 254



 Score =  167 bits (424), Expect = 9e-41
 Identities = 109/281 (38%), Positives = 140/281 (49%), Gaps = 40/281 (14%)

Query: 450 EDAAQGIAHEDAAQGIAHEDA----VQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPD 505
           E + + + H+D   G    +     V  +  E   H    E   H + N+DA+H I   D
Sbjct: 88  EASEESLVHKDRGDGERPVNVRVVQVAPLRRESTPH----EDTVHNITNEDASHDITNED 143

Query: 506 AARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIA 565
           A  GIANE AAQGIA ED A GIANEDA HG+A+E AA G+ANE AA          GIA
Sbjct: 144 AVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQ---------GIA 194

Query: 566 NEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQ 625
           NE A QGIA ED   GIANEDAAHG+ANE AVHG+A ED+V  +ANEDA++ +AN+    
Sbjct: 195 NEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIANDTVQG 254

Query: 626 GIAKEVTAHGVANEDAVQGVVN------------EDALHGVVANEDAAQAIAKPDAAHGI 673
            + + +    +        V+             + +L   +       A  K      +
Sbjct: 255 TLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRAL 314

Query: 674 -----------ANEVAAHGIANEDAAQGIANEDAAQGIANE 703
                      AN    H IANED+   IANE A   IAN+
Sbjct: 315 YTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIAND 355



 Score =  167 bits (423), Expect = 1e-40
 Identities = 103/239 (43%), Positives = 130/239 (54%), Gaps = 8/239 (3%)

Query: 1445 NEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAR 1504
            +ED    I NEDA+  I +EDAV GIANE A  G+A E AA G+ANEDAAH IA  DAA+
Sbjct: 123  HEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQ 182

Query: 1505 GIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEV 1564
            GIANEVA QGIA ED A GIANEDA HG+ANE AA GIANE AVHG+A ED+V  +  E 
Sbjct: 183  GIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242

Query: 1565 TAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGI 1624
              + +AN D VQG +      + +       ++ +      +   +   S+        +
Sbjct: 243  AIYDIAN-DTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSL 301

Query: 1625 ANQDAAQGIANEVAAHGI------SKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQG 1677
                        +    +      +  D V  IANED+   IANE A   IA+ D VQG
Sbjct: 302  MTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIAN-DTVQG 359



 Score =  167 bits (423), Expect = 1e-40
 Identities = 106/243 (43%), Positives = 129/243 (53%), Gaps = 31/243 (12%)

Query: 1950 NEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAH 2009
            +ED    I NE A+H I NEDA  GIANE AAQGIA+EDA QGIANEDA HG+A+EDAA 
Sbjct: 123  HEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQ 182

Query: 2010 AIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEG 2069
             IA   AA+GIANE AAQGIA ED   GIANEDAAHG+ANEDA   IA  D+ + IAN  
Sbjct: 183  GIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIAN-- 240

Query: 2070 IATEDVADGIAEDAVQG-ITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDA 2128
               ED    IA D VQG +T      ++ +      + +      +T  +    +     
Sbjct: 241  ---EDAIYDIANDTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLY 297

Query: 2129 AHGV------------------------ANEVAAHGVANEDAAQGVANEVAAQGVANEDA 2164
               +                        AN    H +ANED+   +ANE A   +AN D 
Sbjct: 298  TTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIAN-DT 356

Query: 2165 VQG 2167
            VQG
Sbjct: 357  VQG 359



 Score =  167 bits (423), Expect = 1e-40
 Identities = 87/134 (64%), Positives = 103/134 (76%), Gaps = 2/134 (1%)

Query: 1580 NEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAA 1639
            +ED +H++  NEDA+  I   DA HGIANE AA  IAN+DAAQGIAN+DAA GIA+E AA
Sbjct: 123  HEDTVHNIT-NEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAA 181

Query: 1640 HGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANE 1699
             GI+ E A QGIANEDAAQGIANEDA  GIA+EDA  GIANEDAVHG+A E + + +ANE
Sbjct: 182  QGIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANE 241

Query: 1700 DPVQGVANEDAVQG 1713
            D +  +AN D VQG
Sbjct: 242  DAIYDIAN-DTVQG 254



 Score =  166 bits (421), Expect = 2e-40
 Identities = 103/241 (42%), Positives = 135/241 (56%), Gaps = 18/241 (7%)

Query: 422 NEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVH 481
           +ED    I NE A+H I+ EDAV GIANE AAQGIA+EDAAQGIA+EDA  GIA+EDA  
Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQ 182

Query: 482 GVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEV 541
           G+A EVAA G+AN+DAA  IA  DA  GIANE AA GIA ED   GIANED+V+ +ANE 
Sbjct: 183 GIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242

Query: 542 AAHGVANEDAAHAIA-------------KPDAAHGIANEVATQGIATEDVADGIANED-- 586
           A + +AN+     +              K      +     T+ +    +   +      
Sbjct: 243 AIYDIANDTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSLM 302

Query: 587 -AAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGV 645
            A +  +   A++   +    +  AN D VH +ANED+   IA E   + +AN D VQG 
Sbjct: 303 TAPYKTSPMRALYTTLLMIPTRH-ANADTVHDIANEDSVYDIANEGAVYDIAN-DTVQGT 360

Query: 646 V 646
           +
Sbjct: 361 L 361



 Score =  159 bits (401), Expect = 4e-38
 Identities = 102/234 (43%), Positives = 130/234 (55%), Gaps = 9/234 (3%)

Query: 1554 EDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAH 1613
            ED V  +  E  +H + NEDAV G+ NE A   + ANEDAAQ IA  DAAHGIA+E AA 
Sbjct: 124  EDTVHNITNEDASHDITNEDAVHGIANEAAAQGI-ANEDAAQGIANEDAAHGIASEDAAQ 182

Query: 1614 SIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHED 1673
             IAN+ AAQGIAN+DAAQGIANE A HGI+ EDA  GIANEDA  GIANED+   IA+ED
Sbjct: 183  GIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242

Query: 1674 AVQGIANEDAVHGVAKEVAAHGVANEDP----VQGVANEDAVQGVANEVEVQGVAHEDAV 1729
            A+  IAN D V G    +         P    V       ++     +  +    +  ++
Sbjct: 243  AIYDIAN-DTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSL 301

Query: 1730 QGIANEDA---AHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKE 1780
                 + +   A   T  +     AN D    IA+ED+V  IANE AV+ +A +
Sbjct: 302  MTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIAND 355



 Score =  155 bits (393), Expect = 3e-37
 Identities = 108/284 (38%), Positives = 143/284 (50%), Gaps = 19/284 (6%)

Query: 1455 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQG 1514
            E + + + H+D   G   E  V+    +VA   +  E   H     D    I NE A+  
Sbjct: 88   EASEESLVHKDRGDG---ERPVNVRVVQVAP--LRRESTPHE----DTVHNITNEDASHD 138

Query: 1515 IATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDA 1574
            I  ED   GIANE AA G+ANE AAQGIANE A HG+A EDA QG+  EV A G+ANEDA
Sbjct: 139  ITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQGIANEDA 198

Query: 1575 VQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIA 1634
             QG+ NEDA+H  +ANEDAA  IA  DA HGIANE + + IAN+DA   IAN D  QG  
Sbjct: 199  AQGIANEDAVHG-IANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIAN-DTVQGTL 256

Query: 1635 NEV-----AAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAK 1689
              +           K   ++ +      + +      + +     +        +  +  
Sbjct: 257  TRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRALYT 316

Query: 1690 EVAAHGV--ANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQG 1731
             +       AN D V  +ANED+V  +ANE  V  +A+ D VQG
Sbjct: 317  TLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIAN-DTVQG 359



 Score =  154 bits (389), Expect = 1e-36
 Identities = 97/249 (38%), Positives = 131/249 (52%), Gaps = 29/249 (11%)

Query: 885  DAAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDA 944
            D  H I NE  +++     I  ED   GIA +A        AAQ IA +DAA  I NEDA
Sbjct: 125  DTVHNITNEDASHD-----ITNEDAVHGIANEA--------AAQGIANEDAAQGIANEDA 171

Query: 945  AQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAH 1004
            A G+A+EDAA G+ANE AAQG+ANE AAQG+ANEDAVHG+ANEDA  G+ANE  V GIA+
Sbjct: 172  AHGIASEDAAQGIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIAN 231

Query: 1005 KDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGIS----KED 1060
            +D++  IANEDA + IAN+     +        +        +   +    ++    K  
Sbjct: 232  EDSVYDIANEDAIYDIANDTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPS 291

Query: 1061 AVQGIANEDAAQGIANEDAAQGI-----------AHEDAVQGIANEDAVHGVAKEVAAHG 1109
              + +               + +           A+ D V  IANED+V+ +A E A + 
Sbjct: 292  LTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYD 351

Query: 1110 VANEDPVQG 1118
            +AN D VQG
Sbjct: 352  IAN-DTVQG 359



 Score =  149 bits (375), Expect = 4e-35
 Identities = 94/241 (39%), Positives = 122/241 (50%), Gaps = 18/241 (7%)

Query: 1518 EDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQG 1577
            ED    I NEDA+H + NE A  GIANE A  G+A EDA QG+  E  AHG+A+EDA QG
Sbjct: 124  EDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQG 183

Query: 1578 VVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEV 1637
            + NE A   + ANEDAAQ IA  DA HGIANE AAH IAN+DA  GIAN+D+   IANE 
Sbjct: 184  IANEVAAQGI-ANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242

Query: 1638 AAHGISKEDAVQG-----IANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVA 1692
            A + I+  D VQG     +      +        + +      + +        +     
Sbjct: 243  AIYDIAN-DTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSL 301

Query: 1693 AHGVANEDPVQGV-----------ANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGI 1741
                    P++ +           AN D V  +ANE  V  +A+E AV  IAN+     +
Sbjct: 302  MTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIANDTVQGTL 361

Query: 1742 T 1742
            T
Sbjct: 362  T 362



 Score = 34.7 bits (78), Expect = 1.1
 Identities = 16/37 (43%), Positives = 22/37 (59%), Gaps = 1/37 (2%)

Query: 827 ANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVV 863
           AN D VH +ANED+   +A E   + + N D VQG +
Sbjct: 326 ANADTVHDIANEDSVYDIANEGAVYDIAN-DTVQGTL 361



 Score = 32.7 bits (73), Expect = 4.4
 Identities = 14/37 (37%), Positives = 21/37 (56%)

Query: 818 ANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVT 854
           AN D    +ANED+V+ +ANE A   +A +     +T
Sbjct: 326 ANADTVHDIANEDSVYDIANEGAVYDIANDTVQGTLT 362


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score =  125 bits (313), Expect = 6e-28
 Identities = 227/1121 (20%), Positives = 301/1121 (26%), Gaps = 74/1121 (6%)

Query: 405  PDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQG 464
            P    G   E  A G    D   G        G        G+    AAQ     D   G
Sbjct: 133  PRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAG 192

Query: 465  IAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDV 524
             A    +QG        G      A G            P   +G   E    G++    
Sbjct: 193  GAQLGVMQGPMGPMGPRGPPGPAGAPG------------PQGFQGNPGEPGEPGVSGPMG 240

Query: 525  ADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIAN 584
              G        G   E    G A E        P    G      T G+       G   
Sbjct: 241  PRGPPGPPGKPGDDGEAGKPGKAGERG------PPGPQGARGFPGTPGLPGVKGHRGYPG 294

Query: 585  EDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQG 644
             D A G A    V G +      G        G+  E    G A    A G    D   G
Sbjct: 295  LDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARG---NDGQPG 351

Query: 645  VVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEV 704
                    G                A G   E    G    + AQG   E    G     
Sbjct: 352  PAGPPGPVGPAGGPGFP-------GAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPA 404

Query: 705  AAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVA 764
             A G    D + G      A GIA      G        G    +   G   E  + G  
Sbjct: 405  GASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFK 464

Query: 765  NEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQ 824
             E   +G       QG        G A E+   G   E    G       +G        
Sbjct: 465  GEQGPKGEPGPAGPQG------APGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFP 518

Query: 825  GVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKP 884
            G        G   E    G+A    A+G        G+     L G    +   Q    P
Sbjct: 519  GQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGR-PGDAGPQGKVGP 577

Query: 885  DAAHGIANEGVANEVAAQGIATEDVADGI-AKDAAHGITKEEAAQAIAKQDAAHSITNED 943
              A G   +G       QG   +    G      A+G   +   + +        +  +D
Sbjct: 578  SGAPG--EDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKD 635

Query: 944  AAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIA 1003
               G A      G A E   QG       QG+       G   +   QGV  E    G+ 
Sbjct: 636  GETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLV 695

Query: 1004 HKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQ 1063
                 +G   E  + G      A G+       G    D  +G +      G      +Q
Sbjct: 696  GPRGERGFPGERGSPG------AQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQ 749

Query: 1064 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANED 1123
            G+  E  A GIA     +G   E   +G   +D   G+   +   G A            
Sbjct: 750  GMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPA------------ 797

Query: 1124 AVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIA 1183
               G   EV   G A      G A    A G   E    G A      G A    A G  
Sbjct: 798  GANGEKGEVGPPGPA------GSAGARGAPGERGETGPPGPA------GFAGPPGADGQP 845

Query: 1184 HEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVAD 1243
                 QG A +    G        G         +  P  ARG      A G      A 
Sbjct: 846  GAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPG---AA 902

Query: 1244 GIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKED 1303
            G      ++G        G S +D  +G   +    G A E  +QG A     +G   +D
Sbjct: 903  GRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDD 962

Query: 1304 PVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIA 1363
               G       QG+A +  + G+  +   +G        G   +  A G + +       
Sbjct: 963  GPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPV 1022

Query: 1364 NEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQ 1423
                  G + E   +G    D   G      V+G   E    G        G        
Sbjct: 1023 GPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPT 1082

Query: 1424 GIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEV 1483
            G   +    G    +   G A     QG       +G A E   +G+       G+    
Sbjct: 1083 GKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLP 1142

Query: 1484 AAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGI 1524
               G + +  A   A P   RG    V   G   +D A+GI
Sbjct: 1143 GPPGPSGDQGASGPAGPSGPRGPPGPVGPSG---KDGANGI 1180



 Score =  122 bits (307), Expect = 3e-27
 Identities = 202/1045 (19%), Positives = 287/1045 (27%), Gaps = 51/1045 (4%)

Query: 1221 PDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQG 1280
            P    G+    AAQ     D   G A      G    +   G        G        G
Sbjct: 169  PPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPG 228

Query: 1281 IAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDA 1340
               E  V G        G   +    G A +    G       QG        G+     
Sbjct: 229  EPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKG 288

Query: 1341 AHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVAN 1400
              G    D A+G   E  A  +  E  + G +      G       +G        G   
Sbjct: 289  HRGYPGLDGAKG---EAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARG 345

Query: 1401 EDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQG 1460
             D   G A      G A      G      A G   E    G    + AQG   E    G
Sbjct: 346  NDGQPGPAGPPGPVGPAGGPGFPG------APGAKGEAGPTGARGPEGAQGPRGEPGTPG 399

Query: 1461 IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDV 1520
                    G    D + G      A G+A          P   +G    +  +G   E  
Sbjct: 400  SPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPG 459

Query: 1521 ADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVN 1580
              G   E    G       QG        G        G V  +   G       +G   
Sbjct: 460  IAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPG 519

Query: 1581 EDALHSV--VANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVA 1638
            +D L        E     +A P  A+G         +     A+G+  +    G   +V 
Sbjct: 520  QDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG---ARGLTGRPGDAGPQGKVG 576

Query: 1639 AHGISKEDA---------------VQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDA 1683
              G   ED                V G      A G   +   +G+     ++G+  +D 
Sbjct: 577  PSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDG 636

Query: 1684 VHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITN 1743
              G A      G A E   QG       QG+       G   +   QG+  E  A G+  
Sbjct: 637  ETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVG 696

Query: 1744 EVAAHGIANE---DAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDA 1800
                 G   E     AQG+     + G    D     +      G         +     
Sbjct: 697  PRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERG 756

Query: 1801 ARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAK 1860
            A GIA     +G   E   +G P +D   G+   +   G +  +  +G        G A 
Sbjct: 757  AAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAG 816

Query: 1861 EDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQG 1920
                 G   E    G A      G   +  A G   E   +G A     Q  +     QG
Sbjct: 817  ARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQG 876

Query: 1921 ISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDA 1980
             +     +G        G        G      + G        G + +D  +G   +  
Sbjct: 877  PTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSG 936

Query: 1981 AQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIAN 2040
              G A E  +QG A      G   +D       P   +G+A +    G+  +    G   
Sbjct: 937  PPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPG 996

Query: 2041 EDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQD 2100
                 G   +  A     P A+      G        G A +   G      A     +D
Sbjct: 997  LPGPSGEPGKQGA-----PGASGDRGPPGPVGPPGLTGPAGE--PGREGSPGADGPPGRD 1049

Query: 2101 AAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQ------GVANEV 2154
             A G+  +   +G T  V A G      + G A      G   E  AQ      G A   
Sbjct: 1050 GAAGVKGD---RGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGAR 1106

Query: 2155 AAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVA 2214
              QG       +G A E   +G+       G+       G + +  A G A     +G  
Sbjct: 1107 GIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPP 1166

Query: 2215 NEVAAQGVANEDAAQGVANEVAVHG 2239
              V   G + +D A G+   +   G
Sbjct: 1167 GPV---GPSGKDGANGIPGPIGPPG 1188



 Score =  118 bits (295), Expect = 8e-26
 Identities = 214/1061 (20%), Positives = 291/1061 (27%), Gaps = 74/1061 (6%)

Query: 1231 VAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGI 1290
            V    I  EDV D ++ E    G    +    ++      G   +    G  K+  + G 
Sbjct: 62   VLCDDIICEDVKDCLSPE-IPFGECCPICPTDLATASGQPGPKGQKGEPGDIKD--IVGP 118

Query: 1291 ANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAA 1350
                  QG A E   +G       +G   E    G    D   G        G       
Sbjct: 119  KGPPGPQGPAGEQGPRGD------RGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGP 172

Query: 1351 QGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANE 1410
             G+    AAQ     D   G ++   +QG       +G        G       QG   E
Sbjct: 173  PGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRG---PPGPAGAPGPQGFQGNPGE 229

Query: 1411 VEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGI 1470
                GV+     +G        G   E    G A E    G        G      V+G 
Sbjct: 230  PGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGH 289

Query: 1471 ANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAA 1530
                 + G   E  A GV  E  +          G    +  +G+  E    G A    A
Sbjct: 290  RGYPGLDGAKGEAGAPGVKGESGS------PGENGSPGPMGPRGLPGERGRTGPAGAAGA 343

Query: 1531 HGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVAN 1590
             G   +    G    V   G        G   E    G    +  QG   E        +
Sbjct: 344  RGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPG---TPGS 400

Query: 1591 EDAAQAIAKP--DAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAV 1648
               A A   P  D   G      A  IA      G       QG    +   G + E  +
Sbjct: 401  PGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGI 460

Query: 1649 QGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANE 1708
             G   E   +G       QG        G A E+   G   E    G       +G    
Sbjct: 461  AGFKGEQGPKGEPGPAGPQG------APGPAGEEGKRGARGEPGGVGPIGPPGERGAPGN 514

Query: 1709 DAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGI 1768
                G       +G   E    G+A    A+G        G+       G   +   QG 
Sbjct: 515  RGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQG- 573

Query: 1769 ANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAA 1828
                       +V   G   ED       P  ARG    +            G P    A
Sbjct: 574  -----------KVGPSGAPGEDGRPGPPGPQGARGQPGVM------------GFPGPKGA 610

Query: 1829 HGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANE 1888
            +G   +    G+     ++G+  +D   G A      G A E   QG       QG+   
Sbjct: 611  NGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGP 670

Query: 1889 DAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGI 1948
                G   +   QG+  E  A  +      +G   E    G      AQG+     + G 
Sbjct: 671  PGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPG------AQGLQGPRGLPGT 724

Query: 1949 ANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAA 2008
               D  +G +      G       QG+  E  A GIA     +G   E    G   +D  
Sbjct: 725  PGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGG 784

Query: 2009 HAIAKP------DAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAA 2062
              +  P        A G   EV   G A    A G   E    G          A P  A
Sbjct: 785  RGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGE---RGETGPPGPAGFAGPPGA 841

Query: 2063 HGIANEGIATEDVADGIAEDA----VQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEV 2118
             G    G   E    G   DA     QG +     Q         G        G T   
Sbjct: 842  DG--QPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFP 899

Query: 2119 AAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIA 2178
             A G      ++G        G + +D  +G   +    G A E  +QG A     +G  
Sbjct: 900  GAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEP 959

Query: 2179 HKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVH 2238
              D   G       QG+A +    G+  +   +G        G   +  A G + +    
Sbjct: 960  GDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPP 1019

Query: 2239 GVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVHGIANE 2279
            G          A E   +G    D   G      V G   E
Sbjct: 1020 GPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGE 1060



 Score =  115 bits (289), Expect = 4e-25
 Identities = 218/1118 (19%), Positives = 299/1118 (26%), Gaps = 75/1118 (6%)

Query: 667  PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG 726
            P    G   E  A G    D   G        G        G+    A Q     D   G
Sbjct: 133  PRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAG 192

Query: 727  IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDA 786
             A    +QG        G      A G       QG   E    GV+  +  +G      
Sbjct: 193  GAQLGVMQGPMGPMGPRGPPGPAGAPGPQG---FQGNPGEPGEPGVSGPMGPRGPPGPPG 249

Query: 787  VQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAK 846
              G   E    G A E    G        G       +G      + G   E  A GV  
Sbjct: 250  KPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKG 309

Query: 847  EVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIAT 906
            E    G   E+   G +    L G       A       AA    N+G        G   
Sbjct: 310  E---SGSPGENGSPGPMGPRGLPGERGRTGPA------GAAGARGNDGQPGPAGPPGPVG 360

Query: 907  EDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGV 966
               A G     A G   E         + A     E    G      A G    D   G 
Sbjct: 361  P--AGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGA 418

Query: 967  ANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGI---ANE 1023
                 A G+A      G       QG    +  +G   +  I G   E    G    A  
Sbjct: 419  KGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGP 478

Query: 1024 VAAHGIANEDAAQGIANEDAAQGIANEVAAHG------ISKEDAV---QGIANEDAAQGI 1074
              A G A E+  +G   E    G        G         +D +   +G   E    G+
Sbjct: 479  QGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGL 538

Query: 1075 ANEDAAQGIAHEDA------VQGIANEDAVHGVAKEVAAHGVANEDP------VQGVANE 1122
            A    A G             +G+       G   +V   G   ED        QG   +
Sbjct: 539  AGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ 598

Query: 1123 DAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGI 1182
              V G        G   +   +G+       G+  +    G A      G A E   QG 
Sbjct: 599  PGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGA 658

Query: 1183 AHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVA 1242
                  QG+       G   +    GV  E  A  +  P   RG   E  + G      A
Sbjct: 659  PGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPG------A 712

Query: 1243 DGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKE 1302
             G+       G        G S      G       QG+  E    GIA     +G   E
Sbjct: 713  QGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGE 772

Query: 1303 DPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDI 1362
               +G   +D  +G+   +   G A  +  +G        G A    A G   E      
Sbjct: 773  KGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGP 832

Query: 1363 ANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAV 1422
            A      G   +   +G   E   +G A     QG +     QG       +G       
Sbjct: 833  AGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP 892

Query: 1423 QGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE 1482
             G      A G      ++G        G + +D  +G   +    G A E  + G A  
Sbjct: 893  PGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGP 952

Query: 1483 VAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGI 1542
                G   +D       P   +G+A +    G+  +    G        G   +  A G 
Sbjct: 953  PGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGA 1012

Query: 1543 ANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDA 1602
            + +    G      + G   E    G    D   G    D    V  +     A+  P A
Sbjct: 1013 SGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPG---RDGAAGVKGDRGETGAVGAPGA 1069

Query: 1603 AHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAN 1662
                              + G A     QG   E  A G        G       QG   
Sbjct: 1070 P-------------GPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRG 1116

Query: 1663 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQG 1722
            +   +G A E   +G+       G+       G + +    G A     +G    V    
Sbjct: 1117 D---KGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPV---- 1169

Query: 1723 VAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIA 1760
                    G + +D A+GI   +   G        G A
Sbjct: 1170 --------GPSGKDGANGIPGPIGPPGPRGRSGETGPA 1199



 Score =  115 bits (287), Expect = 7e-25
 Identities = 197/1028 (19%), Positives = 277/1028 (26%), Gaps = 61/1028 (5%)

Query: 65   AHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVAN 124
            A G      + GV      +G    D A G A      G +      G    +  +G+  
Sbjct: 274  ARGFPGTPGLPGVKGH---RGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPG 330

Query: 125  EDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQD 184
            E    G A     +G   +    G        G      A G   E         + AQ 
Sbjct: 331  ERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQG 390

Query: 185  IANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVE 244
               E    G        G    D   G        G+A      G       QG    + 
Sbjct: 391  PRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLG 450

Query: 245  VQGVAHEDAVQGIANEDAAHGITNEV---AAHGIANEDAAQGIANEDAAQGIAHEDAVQG 301
             +G   E  + G   E    G         A G A E+  +G   E    G       +G
Sbjct: 451  PKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERG 510

Query: 302  IANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDA 361
                    G        G   E     +A P  A+G        G+     A G+     
Sbjct: 511  APGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG---ARGLTGRPG 567

Query: 362  AHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIA 421
              G   +V   G   ED   G        G                  G      A+G  
Sbjct: 568  DAGPQGKVGPSGAPGEDGRPGPPGPQGARG-------------QPGVMGFPGPKGANGEP 614

Query: 422  NEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVH 481
             +   +G+       G+  +D   G A      G A E   QG       QG+       
Sbjct: 615  GKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPP 674

Query: 482  GVAKEVAAHGVANKDAAHAIAKPDAARGIANE---VAAQGIATEDVADGIANEDAVHGVA 538
            G   +    GV  +  A  +  P   RG   E     AQG+       G    D   G +
Sbjct: 675  GEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGAS 734

Query: 539  NEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVH 598
                  G         +     A GIA     +G   E   +G   +D   G+   +   
Sbjct: 735  GPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPP 794

Query: 599  GVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGV--VA 656
            G A  +  +G        G A    A G   E    G A      G   +    G    A
Sbjct: 795  GPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEA 854

Query: 657  NEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQ 716
             +        P    G        G+     A+G      A G      A G        
Sbjct: 855  GQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFP---GAAGRVGPPGSN 911

Query: 717  GIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEV 776
            G        G + +D  +G   +    G A E    G A     +G   +D   G     
Sbjct: 912  GNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPP 971

Query: 777  EVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVA 836
              QG+A +  + G+  +    G        G   +  A G + +    G      + G A
Sbjct: 972  GPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA 1031

Query: 837  NEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVA 896
             E   +G      A G    D   GV  +    G V    A      P  A     +G  
Sbjct: 1032 GEPGREG---SPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDR 1088

Query: 897  NEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHG 956
             E  AQG        G     A GI   +  +                 +G A E    G
Sbjct: 1089 GEAGAQGPMGPSGPAG-----ARGIQGPQGPR---------------GDKGEAGEPGERG 1128

Query: 957  VANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDA 1016
            +       G+       G + +    G A     +G    V   G + KD   GI     
Sbjct: 1129 LKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPV---GPSGKDGANGIPGPIG 1185

Query: 1017 AHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAH-GISKE----DAVQGIANEDAA 1071
              G        G A      G        G   +++A  G+       D +Q +  + AA
Sbjct: 1186 PPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAA 1245

Query: 1072 QGIANEDA 1079
             G+   DA
Sbjct: 1246 GGLRQHDA 1253



 Score =  114 bits (284), Expect = 1e-24
 Identities = 203/1050 (19%), Positives = 280/1050 (26%), Gaps = 75/1050 (7%)

Query: 1253 GVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANED 1312
            G   E  A G    D   G        G        G+    AAQ     D   G A   
Sbjct: 138  GDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLG 197

Query: 1313 PIQGVANEVEVQGV---AHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQ 1369
             +QG    +  +G    A     QG        G        G            +D   
Sbjct: 198  VMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEA 257

Query: 1370 GISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANED 1429
            G   +   +G      A+G      + GV       G+      +G A    V+G +   
Sbjct: 258  GKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDG---AKGEAGAPGVKGESGSP 314

Query: 1430 AAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVA 1489
              +G    +   G+  E    G A    A+G   +    G        G      A G  
Sbjct: 315  GENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAK 374

Query: 1490 NEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVH 1549
             E        P+ A+G   E  T G      A G    D   G      A GIA      
Sbjct: 375  GEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFP 434

Query: 1550 GVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVV--ANEDAAQAIAKPDAAHGIA 1607
            G       QG    +   G   E  + G   E         A    A   A  +   G  
Sbjct: 435  GPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGAR 494

Query: 1608 NEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQ 1667
             E            +G        G        G   E    G+A    A G        
Sbjct: 495  GEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEP 554

Query: 1668 GIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDP---------------VQGVANEDAVQ 1712
            G+      +G+       G   +V   G   ED                V G        
Sbjct: 555  GLP---GARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGAN 611

Query: 1713 GVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANED 1772
            G   +   +G+     ++G+  +D   G        G A E   QG       QG+    
Sbjct: 612  GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPP 671

Query: 1773 AVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANE---VAAQGIATEDVADGIPNEDAAH 1829
                   +    GV  E  A  +  P   RG   E     AQG+       G P  D   
Sbjct: 672  GPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPK 731

Query: 1830 GVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANED 1889
            G +      G      +QG+  E  A GIA     +G   E   +G   +D  +G+    
Sbjct: 732  GASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPI 791

Query: 1890 AAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIA 1949
               G A  +  +G          A    A G   E    G A      G A      G  
Sbjct: 792  GPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPA------GFAGPPGADG-- 843

Query: 1950 NEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAH 2009
             +  A+G   E    G A     QG +     QG       +G        G      A 
Sbjct: 844  -QPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAA 902

Query: 2010 AIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEG 2069
                P  + G        G + +D   G   +    G A E   Q  A P    G   + 
Sbjct: 903  GRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGD- 961

Query: 2070 IATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAA 2129
                        D   G       Q +A Q    G+  +   +G        G   +  A
Sbjct: 962  ------------DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGA 1009

Query: 2130 HGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANE 2189
             G + +    G        G A E   +G    D   G            +D   G+  +
Sbjct: 1010 PGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPG------------RDGAAGVKGD 1057

Query: 2190 DAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGV---ANEVAVHGVANEDAA 2246
               +G    V A G      + G A     QG   E  AQG    +      G+      
Sbjct: 1058 ---RGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGP 1114

Query: 2247 RHMAKEDAAQGIANEDAAHGIANEDAVHGI 2276
            R        +G A E    G+       G+
Sbjct: 1115 R------GDKGEAGEPGERGLKGHRGFTGL 1138



 Score =  110 bits (274), Expect = 2e-23
 Identities = 227/1147 (19%), Positives = 304/1147 (26%), Gaps = 102/1147 (8%)

Query: 689  QGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE 748
            QG A E   +G        G   E    G    D   G        G        G+   
Sbjct: 125  QGPAGEQGPRG------DRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGN 178

Query: 749  VAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGV 808
             AA      D   G A   V+QG    +  +G        G A      G        G 
Sbjct: 179  FAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRG------PPGPAGAPGPQGFQGNPGEPGE 232

Query: 809  ANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEAL 868
                   G        G   +D   G   +   +G      A G      + GV      
Sbjct: 233  PGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGY 292

Query: 869  HGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQ 928
             G+                     +G   E  A G+  E  + G      +G       +
Sbjct: 293  PGL---------------------DGAKGEAGAPGVKGESGSPG-----ENGSPGPMGPR 326

Query: 929  AIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVA---AQGVANEDAVHGVA 985
             +  +      T    A G    D   G A      G A       A G   E    G  
Sbjct: 327  GLPGERGR---TGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGAR 383

Query: 986  NEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQ 1045
              +  QG   E    G        G    D   G      A GIA      G       Q
Sbjct: 384  GPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQ 443

Query: 1046 GIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEV 1105
            G    +   G + E  + G   E   +G       QG        G A E+   G   E 
Sbjct: 444  GATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQG------APGPAGEEGKRGARGEP 497

Query: 1106 AAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIA 1165
               G       +G        G       +G   E    G+A    A+G        G+ 
Sbjct: 498  GGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLP 557

Query: 1166 NEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAR 1225
                  G   +   QG                     +V   G   ED       P  AR
Sbjct: 558  GARGLTGRPGDAGPQG---------------------KVGPSGAPGEDGRPGPPGPQGAR 596

Query: 1226 GIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKED 1285
            G   +    G      A+G   +    G+       G+  +D   G A      G A E 
Sbjct: 597  G---QPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGER 653

Query: 1286 AVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANE---DAAH 1342
              QG       QG+       G   +   QGV  E    G+      +G   E     A 
Sbjct: 654  GEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQ 713

Query: 1343 GIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANED 1402
            G+       G    D  +  +      G      +QG+  E  A GIA     +G   E 
Sbjct: 714  GLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEK 773

Query: 1403 AVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIA 1462
              +G   +   +G+       G A    A+G   EV   G A    A+G   E    G  
Sbjct: 774  GPEGAPGKDGGRGLTGPIGPPGPA---GANGEKGEVGPPGPAGSAGARGAPGERGETGPP 830

Query: 1463 HEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVAD 1522
                  G    D   G   E    G   +  A     P  A G        G      A 
Sbjct: 831  GPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQ 890

Query: 1523 GIANEDAAHGVANEV---AAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVV 1579
            G        G A  V    + G        G + +D  +G   +    G A E  +QG  
Sbjct: 891  GPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPA 950

Query: 1580 NEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAA 1639
                       +D       P    G+A +     +  +   +G        G   +  A
Sbjct: 951  GPPG-EKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGA 1009

Query: 1640 HGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE---VAAHGV 1696
             G S +    G        G A E   +G    D   G      V G   E   V A G 
Sbjct: 1010 PGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGA 1069

Query: 1697 ANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAA 1756
                   G A     QG   E   QG        G +    A GI       G       
Sbjct: 1070 PGPPGSPGPAGPTGKQGDRGEAGAQG------PMGPSGPAGARGIQGPQGPRG------D 1117

Query: 1757 QGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATE 1816
            +G A E   +G+        +       G + +  A   A P   RG    V   G   +
Sbjct: 1118 KGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSG---K 1174

Query: 1817 DVADGIP 1823
            D A+GIP
Sbjct: 1175 DGANGIP 1181



 Score =  108 bits (269), Expect = 8e-23
 Identities = 222/1123 (19%), Positives = 299/1123 (26%), Gaps = 69/1123 (6%)

Query: 75   QGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANE 134
            +G   E  A G    D   G        G        G+    AAQ     D   G A  
Sbjct: 137  RGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQL 196

Query: 135  DAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQGI 194
              +QG       +G      A G       QG   E     ++     +         G 
Sbjct: 197  GVMQGPMGPMGPRGPPGPAGAPG---PQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGD 253

Query: 195  SKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAV 254
              E    G A E    G        G      V+G      + G   E    GV  E   
Sbjct: 254  DGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGS 313

Query: 255  QGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE 314
             G       +G    +   G+  E    G A    A+G   +    G        G    
Sbjct: 314  PG------ENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGF 367

Query: 315  VAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKEVTAHGV 374
              A G   E        P+ A G   E  T G      A G    D   G      A G+
Sbjct: 368  PGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGI 427

Query: 375  ANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVA 434
            A      G        G             P    G   E    G   E   +G      
Sbjct: 428  AGAPGFPGPRGPPGPQGATG----------PLGPKGQTGEPGIAGFKGEQGPKGEPGPAG 477

Query: 435  AHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVAN 494
              G        G A E+  +G   E    G       +G        G        G   
Sbjct: 478  PQG------APGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPG 531

Query: 495  KDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHA 554
            +     +A P  A G        G+     A G+       G   +V   G   ED    
Sbjct: 532  ERGPSGLAGPKGANGDPGRPGEPGLPG---ARGLTGRPGDAGPQGKVGPSGAPGEDGRPG 588

Query: 555  IAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDA 614
               P  A G   +    G      A+G   +    G+     + G+  +D   G A    
Sbjct: 589  PPGPQGARG---QPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPG 645

Query: 615  VHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIA 674
              G A E   QG        G+       G   +    GV   E  A  +  P    G  
Sbjct: 646  PAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGV-PGEAGAPGLVGPRGERGFP 704

Query: 675  NE---VAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHED 731
             E     A G+       G    D  +G +      G      +QG+  E  A GIA   
Sbjct: 705  GERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPK 764

Query: 732  AVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIA 791
              +G   E    G   +    G+       G A  +   G   EV   G A      G A
Sbjct: 765  GDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGAN---GEKGEVGPPGPA------GSA 815

Query: 792  NEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAH 851
                A G   E    G A      G   +  A+G   E    G A     QG +      
Sbjct: 816  GARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQ 875

Query: 852  GVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVAD 911
            G T     +G    +   G      AA  +  P       + G        G + +D   
Sbjct: 876  GPTGVTGPKGARGAQGPPGATGFPGAAGRVGPP------GSNGNPGPPGPPGPSGKDGPK 929

Query: 912  GIAKDAAH-GITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEV 970
            G   D+   G   E   Q  A          +D   G        G+A +    G+  + 
Sbjct: 930  GARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQR 989

Query: 971  AAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIA 1030
              +G        G   +    G + +    G      + G A E    G      A G  
Sbjct: 990  GERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREG---SPGADGPP 1046

Query: 1031 NEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGI------A 1084
              D A G+  +   +G    V A G        G A     QG   E  AQG       A
Sbjct: 1047 GRDGAAGVKGD---RGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPA 1103

Query: 1085 HEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQ 1144
                +QG        G A E    G+       G+       G + +    G A     +
Sbjct: 1104 GARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPR 1163

Query: 1145 GI------ANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQG 1181
            G       + +D A+GI   +   G        G A      G
Sbjct: 1164 GPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPG 1206



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 91/471 (19%), Positives = 129/471 (27%), Gaps = 25/471 (5%)

Query: 63   DAAHGITNEDAVQGVANEVAAQGVANEDAAHGVA---------NEVAAHGVANEDAAQGV 113
            D   G +      G       QG+  E  A G+A          E    G   +D  +G+
Sbjct: 728  DGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGL 787

Query: 114  ANEVAAQGVANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAA 173
               +   G A  +  +G        G A      G   E    G A      G   +  A
Sbjct: 788  TGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGA 847

Query: 174  QDIAKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANE 233
            +    E   +  A     QG S     QG       +G        G        G    
Sbjct: 848  KGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGP 907

Query: 234  DAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGI 293
                G        G + +D  +G   +    G   E    G A     +G   +D   G 
Sbjct: 908  PGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGA 967

Query: 294  AHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVA 353
                  QG+A +  + G+  +    G               A G + +    G       
Sbjct: 968  EGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGL 1027

Query: 354  DGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIAN 413
             G A E    G      A G    D   GV  +    G V     A     P  + G A 
Sbjct: 1028 TGPAGEPGREG---SPGADGPPGRDGAAGVKGDRGETGAV----GAPGAPGPPGSPGPAG 1080

Query: 414  EVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQG 473
                 G   E  AQG    +   G +    +QG       +G A E   +G+       G
Sbjct: 1081 PTGKQGDRGEAGAQG---PMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTG 1137

Query: 474  IANEDAVHGVAKEVAAHGVANKDAAHAIAKP------DAARGIANEVAAQG 518
            +       G + +  A G A          P      D A GI   +   G
Sbjct: 1138 LQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPG 1188


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score =  125 bits (313), Expect = 6e-28
 Identities = 227/1121 (20%), Positives = 301/1121 (26%), Gaps = 74/1121 (6%)

Query: 405  PDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQG 464
            P    G   E  A G    D   G        G        G+    AAQ     D   G
Sbjct: 64   PRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAG 123

Query: 465  IAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDV 524
             A    +QG        G      A G            P   +G   E    G++    
Sbjct: 124  GAQLGVMQGPMGPMGPRGPPGPAGAPG------------PQGFQGNPGEPGEPGVSGPMG 171

Query: 525  ADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIAN 584
              G        G   E    G A E        P    G      T G+       G   
Sbjct: 172  PRGPPGPPGKPGDDGEAGKPGKAGERG------PPGPQGARGFPGTPGLPGVKGHRGYPG 225

Query: 585  EDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQG 644
             D A G A    V G +      G        G+  E    G A    A G    D   G
Sbjct: 226  LDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARG---NDGQPG 282

Query: 645  VVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEV 704
                    G                A G   E    G    + AQG   E    G     
Sbjct: 283  PAGPPGPVGPAGGPGFP-------GAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPA 335

Query: 705  AAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVA 764
             A G    D + G      A GIA      G        G    +   G   E  + G  
Sbjct: 336  GASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFK 395

Query: 765  NEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQ 824
             E   +G       QG        G A E+   G   E    G       +G        
Sbjct: 396  GEQGPKGEPGPAGPQG------APGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFP 449

Query: 825  GVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKP 884
            G        G   E    G+A    A+G        G+     L G    +   Q    P
Sbjct: 450  GQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGR-PGDAGPQGKVGP 508

Query: 885  DAAHGIANEGVANEVAAQGIATEDVADGI-AKDAAHGITKEEAAQAIAKQDAAHSITNED 943
              A G   +G       QG   +    G      A+G   +   + +        +  +D
Sbjct: 509  SGAPG--EDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKD 566

Query: 944  AAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIA 1003
               G A      G A E   QG       QG+       G   +   QGV  E    G+ 
Sbjct: 567  GETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLV 626

Query: 1004 HKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQ 1063
                 +G   E  + G      A G+       G    D  +G +      G      +Q
Sbjct: 627  GPRGERGFPGERGSPG------AQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQ 680

Query: 1064 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANED 1123
            G+  E  A GIA     +G   E   +G   +D   G+   +   G A            
Sbjct: 681  GMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPA------------ 728

Query: 1124 AVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIA 1183
               G   EV   G A      G A    A G   E    G A      G A    A G  
Sbjct: 729  GANGEKGEVGPPGPA------GSAGARGAPGERGETGPPGPA------GFAGPPGADGQP 776

Query: 1184 HEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVAD 1243
                 QG A +    G        G         +  P  ARG      A G      A 
Sbjct: 777  GAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPG---AA 833

Query: 1244 GIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKED 1303
            G      ++G        G S +D  +G   +    G A E  +QG A     +G   +D
Sbjct: 834  GRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDD 893

Query: 1304 PVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIA 1363
               G       QG+A +  + G+  +   +G        G   +  A G + +       
Sbjct: 894  GPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPV 953

Query: 1364 NEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQ 1423
                  G + E   +G    D   G      V+G   E    G        G        
Sbjct: 954  GPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPT 1013

Query: 1424 GIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEV 1483
            G   +    G    +   G A     QG       +G A E   +G+       G+    
Sbjct: 1014 GKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLP 1073

Query: 1484 AAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGI 1524
               G + +  A   A P   RG    V   G   +D A+GI
Sbjct: 1074 GPPGPSGDQGASGPAGPSGPRGPPGPVGPSG---KDGANGI 1111



 Score =  122 bits (307), Expect = 3e-27
 Identities = 202/1045 (19%), Positives = 287/1045 (27%), Gaps = 51/1045 (4%)

Query: 1221 PDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQG 1280
            P    G+    AAQ     D   G A      G    +   G        G        G
Sbjct: 100  PPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPG 159

Query: 1281 IAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDA 1340
               E  V G        G   +    G A +    G       QG        G+     
Sbjct: 160  EPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKG 219

Query: 1341 AHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVAN 1400
              G    D A+G   E  A  +  E  + G +      G       +G        G   
Sbjct: 220  HRGYPGLDGAKG---EAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARG 276

Query: 1401 EDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQG 1460
             D   G A      G A      G      A G   E    G    + AQG   E    G
Sbjct: 277  NDGQPGPAGPPGPVGPAGGPGFPG------APGAKGEAGPTGARGPEGAQGPRGEPGTPG 330

Query: 1461 IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDV 1520
                    G    D + G      A G+A          P   +G    +  +G   E  
Sbjct: 331  SPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPG 390

Query: 1521 ADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVN 1580
              G   E    G       QG        G        G V  +   G       +G   
Sbjct: 391  IAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPG 450

Query: 1581 EDALHSV--VANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVA 1638
            +D L        E     +A P  A+G         +     A+G+  +    G   +V 
Sbjct: 451  QDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG---ARGLTGRPGDAGPQGKVG 507

Query: 1639 AHGISKEDA---------------VQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDA 1683
              G   ED                V G      A G   +   +G+     ++G+  +D 
Sbjct: 508  PSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDG 567

Query: 1684 VHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITN 1743
              G A      G A E   QG       QG+       G   +   QG+  E  A G+  
Sbjct: 568  ETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVG 627

Query: 1744 EVAAHGIANE---DAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDA 1800
                 G   E     AQG+     + G    D     +      G         +     
Sbjct: 628  PRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERG 687

Query: 1801 ARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAK 1860
            A GIA     +G   E   +G P +D   G+   +   G +  +  +G        G A 
Sbjct: 688  AAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAG 747

Query: 1861 EDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQG 1920
                 G   E    G A      G   +  A G   E   +G A     Q  +     QG
Sbjct: 748  ARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQG 807

Query: 1921 ISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDA 1980
             +     +G        G        G      + G        G + +D  +G   +  
Sbjct: 808  PTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSG 867

Query: 1981 AQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIAN 2040
              G A E  +QG A      G   +D       P   +G+A +    G+  +    G   
Sbjct: 868  PPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPG 927

Query: 2041 EDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQD 2100
                 G   +  A     P A+      G        G A +   G      A     +D
Sbjct: 928  LPGPSGEPGKQGA-----PGASGDRGPPGPVGPPGLTGPAGE--PGREGSPGADGPPGRD 980

Query: 2101 AAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQ------GVANEV 2154
             A G+  +   +G T  V A G      + G A      G   E  AQ      G A   
Sbjct: 981  GAAGVKGD---RGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGAR 1037

Query: 2155 AAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVA 2214
              QG       +G A E   +G+       G+       G + +  A G A     +G  
Sbjct: 1038 GIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPP 1097

Query: 2215 NEVAAQGVANEDAAQGVANEVAVHG 2239
              V   G + +D A G+   +   G
Sbjct: 1098 GPV---GPSGKDGANGIPGPIGPPG 1119



 Score =  116 bits (291), Expect = 2e-25
 Identities = 197/977 (20%), Positives = 265/977 (27%), Gaps = 65/977 (6%)

Query: 1315 QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKE 1374
            +G   E    G    D   G        G        G+    AAQ     D   G ++ 
Sbjct: 68   RGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQL 127

Query: 1375 DAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGI 1434
              +QG       +G        G       QG   E    GV+     +G        G 
Sbjct: 128  GVMQGPMGPMGPRG---PPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGD 184

Query: 1435 ANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAA 1494
              E    G A E    G        G      V+G      + G   E  A GV  E  +
Sbjct: 185  DGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGS 244

Query: 1495 HAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIE 1554
                      G    +  +G+  E    G A    A G   +    G    V   G    
Sbjct: 245  ------PGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGF 298

Query: 1555 DAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKP--DAAHGIANEVAA 1612
                G   E    G    +  QG   E        +   A A   P  D   G      A
Sbjct: 299  PGAPGAKGEAGPTGARGPEGAQGPRGEPG---TPGSPGPAGASGNPGTDGIPGAKGSAGA 355

Query: 1613 HSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHE 1672
              IA      G       QG    +   G + E  + G   E   +G       QG    
Sbjct: 356  PGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQG---- 411

Query: 1673 DAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGI 1732
                G A E+   G   E    G       +G        G       +G   E    G+
Sbjct: 412  --APGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGL 469

Query: 1733 ANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAA 1792
            A    A+G        G+       G   +   QG            +V   G   ED  
Sbjct: 470  AGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQG------------KVGPSGAPGEDGR 517

Query: 1793 HAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANE 1852
                 P  ARG    +            G P    A+G   +    G+     ++G+  +
Sbjct: 518  PGPPGPQGARGQPGVM------------GFPGPKGANGEPGKAGEKGLPGAPGLRGLPGK 565

Query: 1853 DAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDI 1912
            D   G A      G A E   QG       QG+       G   +   QG+  E  A  +
Sbjct: 566  DGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGL 625

Query: 1913 ANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAA 1972
                  +G   E    G      AQG+     + G    D  +G +      G       
Sbjct: 626  VGPRGERGFPGERGSPG------AQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGL 679

Query: 1973 QGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKP------DAARGIANEVAA 2026
            QG+  E  A GIA     +G   E    G   +D    +  P        A G   EV  
Sbjct: 680  QGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGP 739

Query: 2027 QGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDA--- 2083
             G A    A G   E    G          A P  A G    G   E    G   DA   
Sbjct: 740  PGPAGSAGARGAPGE---RGETGPPGPAGFAGPPGADG--QPGAKGEQGEAGQKGDAGAP 794

Query: 2084 -VQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVA 2142
              QG +     Q         G        G T    A G      ++G        G +
Sbjct: 795  GPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPS 854

Query: 2143 NEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAH 2202
             +D  +G   +    G A E  +QG A     +G    D   G       QG+A +    
Sbjct: 855  GKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIV 914

Query: 2203 GVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANED 2262
            G+  +   +G        G   +  A G + +    G          A E   +G    D
Sbjct: 915  GLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGAD 974

Query: 2263 AAHGIANEDAVHGIANE 2279
               G      V G   E
Sbjct: 975  GPPGRDGAAGVKGDRGE 991



 Score =  115 bits (289), Expect = 4e-25
 Identities = 218/1118 (19%), Positives = 299/1118 (26%), Gaps = 75/1118 (6%)

Query: 667  PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG 726
            P    G   E  A G    D   G        G        G+    A Q     D   G
Sbjct: 64   PRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAG 123

Query: 727  IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDA 786
             A    +QG        G      A G       QG   E    GV+  +  +G      
Sbjct: 124  GAQLGVMQGPMGPMGPRGPPGPAGAPGPQG---FQGNPGEPGEPGVSGPMGPRGPPGPPG 180

Query: 787  VQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAK 846
              G   E    G A E    G        G       +G      + G   E  A GV  
Sbjct: 181  KPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKG 240

Query: 847  EVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIAT 906
            E    G   E+   G +    L G       A       AA    N+G        G   
Sbjct: 241  E---SGSPGENGSPGPMGPRGLPGERGRTGPA------GAAGARGNDGQPGPAGPPGPVG 291

Query: 907  EDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGV 966
               A G     A G   E         + A     E    G      A G    D   G 
Sbjct: 292  P--AGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGA 349

Query: 967  ANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGI---ANE 1023
                 A G+A      G       QG    +  +G   +  I G   E    G    A  
Sbjct: 350  KGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGP 409

Query: 1024 VAAHGIANEDAAQGIANEDAAQGIANEVAAHG------ISKEDAV---QGIANEDAAQGI 1074
              A G A E+  +G   E    G        G         +D +   +G   E    G+
Sbjct: 410  QGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGL 469

Query: 1075 ANEDAAQGIAHEDA------VQGIANEDAVHGVAKEVAAHGVANEDP------VQGVANE 1122
            A    A G             +G+       G   +V   G   ED        QG   +
Sbjct: 470  AGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ 529

Query: 1123 DAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGI 1182
              V G        G   +   +G+       G+  +    G A      G A E   QG 
Sbjct: 530  PGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGA 589

Query: 1183 AHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVA 1242
                  QG+       G   +    GV  E  A  +  P   RG   E  + G      A
Sbjct: 590  PGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPG------A 643

Query: 1243 DGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKE 1302
             G+       G        G S      G       QG+  E    GIA     +G   E
Sbjct: 644  QGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGE 703

Query: 1303 DPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDI 1362
               +G   +D  +G+   +   G A  +  +G        G A    A G   E      
Sbjct: 704  KGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGP 763

Query: 1363 ANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAV 1422
            A      G   +   +G   E   +G A     QG +     QG       +G       
Sbjct: 764  AGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP 823

Query: 1423 QGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE 1482
             G      A G      ++G        G + +D  +G   +    G A E  + G A  
Sbjct: 824  PGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGP 883

Query: 1483 VAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGI 1542
                G   +D       P   +G+A +    G+  +    G        G   +  A G 
Sbjct: 884  PGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGA 943

Query: 1543 ANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDA 1602
            + +    G      + G   E    G    D   G    D    V  +     A+  P A
Sbjct: 944  SGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPG---RDGAAGVKGDRGETGAVGAPGA 1000

Query: 1603 AHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAN 1662
                              + G A     QG   E  A G        G       QG   
Sbjct: 1001 P-------------GPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRG 1047

Query: 1663 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQG 1722
            +   +G A E   +G+       G+       G + +    G A     +G    V    
Sbjct: 1048 D---KGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPV---- 1100

Query: 1723 VAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIA 1760
                    G + +D A+GI   +   G        G A
Sbjct: 1101 --------GPSGKDGANGIPGPIGPPGPRGRSGETGPA 1130



 Score =  115 bits (287), Expect = 7e-25
 Identities = 197/1028 (19%), Positives = 277/1028 (26%), Gaps = 61/1028 (5%)

Query: 65   AHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVAN 124
            A G      + GV      +G    D A G A      G +      G    +  +G+  
Sbjct: 205  ARGFPGTPGLPGVKGH---RGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPG 261

Query: 125  EDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQD 184
            E    G A     +G   +    G        G      A G   E         + AQ 
Sbjct: 262  ERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQG 321

Query: 185  IANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVE 244
               E    G        G    D   G        G+A      G       QG    + 
Sbjct: 322  PRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLG 381

Query: 245  VQGVAHEDAVQGIANEDAAHGITNEV---AAHGIANEDAAQGIANEDAAQGIAHEDAVQG 301
             +G   E  + G   E    G         A G A E+  +G   E    G       +G
Sbjct: 382  PKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERG 441

Query: 302  IANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDA 361
                    G        G   E     +A P  A+G        G+     A G+     
Sbjct: 442  APGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG---ARGLTGRPG 498

Query: 362  AHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIA 421
              G   +V   G   ED   G        G                  G      A+G  
Sbjct: 499  DAGPQGKVGPSGAPGEDGRPGPPGPQGARG-------------QPGVMGFPGPKGANGEP 545

Query: 422  NEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVH 481
             +   +G+       G+  +D   G A      G A E   QG       QG+       
Sbjct: 546  GKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPP 605

Query: 482  GVAKEVAAHGVANKDAAHAIAKPDAARGIANE---VAAQGIATEDVADGIANEDAVHGVA 538
            G   +    GV  +  A  +  P   RG   E     AQG+       G    D   G +
Sbjct: 606  GEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGAS 665

Query: 539  NEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVH 598
                  G         +     A GIA     +G   E   +G   +D   G+   +   
Sbjct: 666  GPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPP 725

Query: 599  GVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGV--VA 656
            G A  +  +G        G A    A G   E    G A      G   +    G    A
Sbjct: 726  GPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEA 785

Query: 657  NEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQ 716
             +        P    G        G+     A+G      A G      A G        
Sbjct: 786  GQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFP---GAAGRVGPPGSN 842

Query: 717  GIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEV 776
            G        G + +D  +G   +    G A E    G A     +G   +D   G     
Sbjct: 843  GNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPP 902

Query: 777  EVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVA 836
              QG+A +  + G+  +    G        G   +  A G + +    G      + G A
Sbjct: 903  GPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA 962

Query: 837  NEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVA 896
             E   +G      A G    D   GV  +    G V    A      P  A     +G  
Sbjct: 963  GEPGREG---SPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDR 1019

Query: 897  NEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHG 956
             E  AQG        G     A GI   +  +                 +G A E    G
Sbjct: 1020 GEAGAQGPMGPSGPAG-----ARGIQGPQGPR---------------GDKGEAGEPGERG 1059

Query: 957  VANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDA 1016
            +       G+       G + +    G A     +G    V   G + KD   GI     
Sbjct: 1060 LKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPV---GPSGKDGANGIPGPIG 1116

Query: 1017 AHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAH-GISKE----DAVQGIANEDAA 1071
              G        G A      G        G   +++A  G+       D +Q +  + AA
Sbjct: 1117 PPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAA 1176

Query: 1072 QGIANEDA 1079
             G+   DA
Sbjct: 1177 GGLRQHDA 1184



 Score =  114 bits (284), Expect = 1e-24
 Identities = 203/1050 (19%), Positives = 280/1050 (26%), Gaps = 75/1050 (7%)

Query: 1253 GVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANED 1312
            G   E  A G    D   G        G        G+    AAQ     D   G A   
Sbjct: 69   GDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLG 128

Query: 1313 PIQGVANEVEVQGV---AHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQ 1369
             +QG    +  +G    A     QG        G        G            +D   
Sbjct: 129  VMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEA 188

Query: 1370 GISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANED 1429
            G   +   +G      A+G      + GV       G+      +G A    V+G +   
Sbjct: 189  GKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDG---AKGEAGAPGVKGESGSP 245

Query: 1430 AAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVA 1489
              +G    +   G+  E    G A    A+G   +    G        G      A G  
Sbjct: 246  GENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAK 305

Query: 1490 NEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVH 1549
             E        P+ A+G   E  T G      A G    D   G      A GIA      
Sbjct: 306  GEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFP 365

Query: 1550 GVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVV--ANEDAAQAIAKPDAAHGIA 1607
            G       QG    +   G   E  + G   E         A    A   A  +   G  
Sbjct: 366  GPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGAR 425

Query: 1608 NEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQ 1667
             E            +G        G        G   E    G+A    A G        
Sbjct: 426  GEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEP 485

Query: 1668 GIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDP---------------VQGVANEDAVQ 1712
            G+      +G+       G   +V   G   ED                V G        
Sbjct: 486  GLP---GARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGAN 542

Query: 1713 GVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANED 1772
            G   +   +G+     ++G+  +D   G        G A E   QG       QG+    
Sbjct: 543  GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPP 602

Query: 1773 AVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANE---VAAQGIATEDVADGIPNEDAAH 1829
                   +    GV  E  A  +  P   RG   E     AQG+       G P  D   
Sbjct: 603  GPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPK 662

Query: 1830 GVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANED 1889
            G +      G      +QG+  E  A GIA     +G   E   +G   +D  +G+    
Sbjct: 663  GASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPI 722

Query: 1890 AAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIA 1949
               G A  +  +G          A    A G   E    G A      G A      G  
Sbjct: 723  GPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPA------GFAGPPGADG-- 774

Query: 1950 NEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAH 2009
             +  A+G   E    G A     QG +     QG       +G        G      A 
Sbjct: 775  -QPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAA 833

Query: 2010 AIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEG 2069
                P  + G        G + +D   G   +    G A E   Q  A P    G   + 
Sbjct: 834  GRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGD- 892

Query: 2070 IATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAA 2129
                        D   G       Q +A Q    G+  +   +G        G   +  A
Sbjct: 893  ------------DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGA 940

Query: 2130 HGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANE 2189
             G + +    G        G A E   +G    D   G            +D   G+  +
Sbjct: 941  PGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPG------------RDGAAGVKGD 988

Query: 2190 DAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGV---ANEVAVHGVANEDAA 2246
               +G    V A G      + G A     QG   E  AQG    +      G+      
Sbjct: 989  ---RGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGP 1045

Query: 2247 RHMAKEDAAQGIANEDAAHGIANEDAVHGI 2276
            R        +G A E    G+       G+
Sbjct: 1046 R------GDKGEAGEPGERGLKGHRGFTGL 1069



 Score =  110 bits (274), Expect = 2e-23
 Identities = 227/1147 (19%), Positives = 304/1147 (26%), Gaps = 102/1147 (8%)

Query: 689  QGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE 748
            QG A E   +G        G   E    G    D   G        G        G+   
Sbjct: 56   QGPAGEQGPRG------DRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGN 109

Query: 749  VAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGV 808
             AA      D   G A   V+QG    +  +G        G A      G        G 
Sbjct: 110  FAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRG------PPGPAGAPGPQGFQGNPGEPGE 163

Query: 809  ANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEAL 868
                   G        G   +D   G   +   +G      A G      + GV      
Sbjct: 164  PGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGY 223

Query: 869  HGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQ 928
             G+                     +G   E  A G+  E  + G      +G       +
Sbjct: 224  PGL---------------------DGAKGEAGAPGVKGESGSPG-----ENGSPGPMGPR 257

Query: 929  AIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVA---AQGVANEDAVHGVA 985
             +  +      T    A G    D   G A      G A       A G   E    G  
Sbjct: 258  GLPGERGR---TGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGAR 314

Query: 986  NEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQ 1045
              +  QG   E    G        G    D   G      A GIA      G       Q
Sbjct: 315  GPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQ 374

Query: 1046 GIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEV 1105
            G    +   G + E  + G   E   +G       QG        G A E+   G   E 
Sbjct: 375  GATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQG------APGPAGEEGKRGARGEP 428

Query: 1106 AAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIA 1165
               G       +G        G       +G   E    G+A    A+G        G+ 
Sbjct: 429  GGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLP 488

Query: 1166 NEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAR 1225
                  G   +   QG                     +V   G   ED       P  AR
Sbjct: 489  GARGLTGRPGDAGPQG---------------------KVGPSGAPGEDGRPGPPGPQGAR 527

Query: 1226 GIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKED 1285
            G   +    G      A+G   +    G+       G+  +D   G A      G A E 
Sbjct: 528  G---QPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGER 584

Query: 1286 AVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANE---DAAH 1342
              QG       QG+       G   +   QGV  E    G+      +G   E     A 
Sbjct: 585  GEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQ 644

Query: 1343 GIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANED 1402
            G+       G    D  +  +      G      +QG+  E  A GIA     +G   E 
Sbjct: 645  GLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEK 704

Query: 1403 AVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIA 1462
              +G   +   +G+       G A    A+G   EV   G A    A+G   E    G  
Sbjct: 705  GPEGAPGKDGGRGLTGPIGPPGPA---GANGEKGEVGPPGPAGSAGARGAPGERGETGPP 761

Query: 1463 HEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVAD 1522
                  G    D   G   E    G   +  A     P  A G        G      A 
Sbjct: 762  GPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQ 821

Query: 1523 GIANEDAAHGVANEV---AAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVV 1579
            G        G A  V    + G        G + +D  +G   +    G A E  +QG  
Sbjct: 822  GPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPA 881

Query: 1580 NEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAA 1639
                       +D       P    G+A +     +  +   +G        G   +  A
Sbjct: 882  GPPG-EKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGA 940

Query: 1640 HGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE---VAAHGV 1696
             G S +    G        G A E   +G    D   G      V G   E   V A G 
Sbjct: 941  PGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGA 1000

Query: 1697 ANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAA 1756
                   G A     QG   E   QG        G +    A GI       G       
Sbjct: 1001 PGPPGSPGPAGPTGKQGDRGEAGAQG------PMGPSGPAGARGIQGPQGPRG------D 1048

Query: 1757 QGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATE 1816
            +G A E   +G+        +       G + +  A   A P   RG    V   G   +
Sbjct: 1049 KGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSG---K 1105

Query: 1817 DVADGIP 1823
            D A+GIP
Sbjct: 1106 DGANGIP 1112



 Score =  108 bits (269), Expect = 8e-23
 Identities = 222/1123 (19%), Positives = 299/1123 (26%), Gaps = 69/1123 (6%)

Query: 75   QGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANE 134
            +G   E  A G    D   G        G        G+    AAQ     D   G A  
Sbjct: 68   RGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQL 127

Query: 135  DAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQGI 194
              +QG       +G      A G       QG   E     ++     +         G 
Sbjct: 128  GVMQGPMGPMGPRGPPGPAGAPG---PQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGD 184

Query: 195  SKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAV 254
              E    G A E    G        G      V+G      + G   E    GV  E   
Sbjct: 185  DGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGS 244

Query: 255  QGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE 314
             G       +G    +   G+  E    G A    A+G   +    G        G    
Sbjct: 245  PG------ENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGF 298

Query: 315  VAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKEVTAHGV 374
              A G   E        P+ A G   E  T G      A G    D   G      A G+
Sbjct: 299  PGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGI 358

Query: 375  ANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVA 434
            A      G        G             P    G   E    G   E   +G      
Sbjct: 359  AGAPGFPGPRGPPGPQGATG----------PLGPKGQTGEPGIAGFKGEQGPKGEPGPAG 408

Query: 435  AHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVAN 494
              G        G A E+  +G   E    G       +G        G        G   
Sbjct: 409  PQG------APGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPG 462

Query: 495  KDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHA 554
            +     +A P  A G        G+     A G+       G   +V   G   ED    
Sbjct: 463  ERGPSGLAGPKGANGDPGRPGEPGLPG---ARGLTGRPGDAGPQGKVGPSGAPGEDGRPG 519

Query: 555  IAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDA 614
               P  A G   +    G      A+G   +    G+     + G+  +D   G A    
Sbjct: 520  PPGPQGARG---QPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPG 576

Query: 615  VHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIA 674
              G A E   QG        G+       G   +    GV   E  A  +  P    G  
Sbjct: 577  PAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGV-PGEAGAPGLVGPRGERGFP 635

Query: 675  NE---VAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHED 731
             E     A G+       G    D  +G +      G      +QG+  E  A GIA   
Sbjct: 636  GERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPK 695

Query: 732  AVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIA 791
              +G   E    G   +    G+       G A  +   G   EV   G A      G A
Sbjct: 696  GDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGAN---GEKGEVGPPGPA------GSA 746

Query: 792  NEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAH 851
                A G   E    G A      G   +  A+G   E    G A     QG +      
Sbjct: 747  GARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQ 806

Query: 852  GVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVAD 911
            G T     +G    +   G      AA  +  P       + G        G + +D   
Sbjct: 807  GPTGVTGPKGARGAQGPPGATGFPGAAGRVGPP------GSNGNPGPPGPPGPSGKDGPK 860

Query: 912  GIAKDAAH-GITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEV 970
            G   D+   G   E   Q  A          +D   G        G+A +    G+  + 
Sbjct: 861  GARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQR 920

Query: 971  AAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIA 1030
              +G        G   +    G + +    G      + G A E    G      A G  
Sbjct: 921  GERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREG---SPGADGPP 977

Query: 1031 NEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGI------A 1084
              D A G+  +   +G    V A G        G A     QG   E  AQG       A
Sbjct: 978  GRDGAAGVKGD---RGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPA 1034

Query: 1085 HEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQ 1144
                +QG        G A E    G+       G+       G + +    G A     +
Sbjct: 1035 GARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPR 1094

Query: 1145 GI------ANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQG 1181
            G       + +D A+GI   +   G        G A      G
Sbjct: 1095 GPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPG 1137



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 91/471 (19%), Positives = 129/471 (27%), Gaps = 25/471 (5%)

Query: 63   DAAHGITNEDAVQGVANEVAAQGVANEDAAHGVA---------NEVAAHGVANEDAAQGV 113
            D   G +      G       QG+  E  A G+A          E    G   +D  +G+
Sbjct: 659  DGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGL 718

Query: 114  ANEVAAQGVANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAA 173
               +   G A  +  +G        G A      G   E    G A      G   +  A
Sbjct: 719  TGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGA 778

Query: 174  QDIAKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANE 233
            +    E   +  A     QG S     QG       +G        G        G    
Sbjct: 779  KGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGP 838

Query: 234  DAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGI 293
                G        G + +D  +G   +    G   E    G A     +G   +D   G 
Sbjct: 839  PGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGA 898

Query: 294  AHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVA 353
                  QG+A +  + G+  +    G               A G + +    G       
Sbjct: 899  EGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGL 958

Query: 354  DGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIAN 413
             G A E    G      A G    D   GV  +    G V     A     P  + G A 
Sbjct: 959  TGPAGEPGREG---SPGADGPPGRDGAAGVKGDRGETGAV----GAPGAPGPPGSPGPAG 1011

Query: 414  EVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQG 473
                 G   E  AQG    +   G +    +QG       +G A E   +G+       G
Sbjct: 1012 PTGKQGDRGEAGAQG---PMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTG 1068

Query: 474  IANEDAVHGVAKEVAAHGVANKDAAHAIAKP------DAARGIANEVAAQG 518
            +       G + +  A G A          P      D A GI   +   G
Sbjct: 1069 LQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPG 1119


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score =  114 bits (285), Expect = 1e-24
 Identities = 195/1014 (19%), Positives = 268/1014 (26%), Gaps = 27/1014 (2%)

Query: 487  VAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGV 546
            ++  G         +  P  A G        G   E  A G        G   +    G 
Sbjct: 175  ISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGE 234

Query: 547  ANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAV 606
            A +        P    G      T G+       G +  D A G A      G       
Sbjct: 235  AGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGE 294

Query: 607  QGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAK 666
             G   +    G+  E    G      A G    D   G        G         A+  
Sbjct: 295  NGAPGQMGPRGLPGERGRPGAPGPAGARG---NDGATGAAGPPGPTGPAGPPGFPGAV-- 349

Query: 667  PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG 726
                 G   E    G    +  QG+  E    G A      G    D   G    + A G
Sbjct: 350  -----GAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPG 404

Query: 727  IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDA 786
            IA      G        G        G + E    G   +   +G    V VQG      
Sbjct: 405  IAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQG------ 458

Query: 787  VQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAK 846
              G A E+   G   E    G+      +G        G        G A E  + G A 
Sbjct: 459  PPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAG 518

Query: 847  EVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIAT 906
               + G        G+   + L G   +         P  A      G      A+G A 
Sbjct: 519  PKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQA- 577

Query: 907  EDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGV 966
              V        A G   +   + +     A     +D   G        G A E   QG 
Sbjct: 578  -GVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGP 636

Query: 967  ANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAA 1026
            A     QG+       G A +   QGV  ++   G +     +G   E    G       
Sbjct: 637  AGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQG------P 690

Query: 1027 HGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHE 1086
             G A    A G    D A+G A    A G      +QG+  E  A G+      +G A  
Sbjct: 691  PGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGP 750

Query: 1087 DAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGI 1146
                G   +D V G+   +   G A     +G +      G        G   E    G 
Sbjct: 751  KGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGP 810

Query: 1147 ANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAA 1206
            A      G   +  A G   +  A+G A      G A      G        G       
Sbjct: 811  AGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGP 870

Query: 1207 HGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKE 1266
             G      A     P    G A      G A ++   G   E    G   EV   G    
Sbjct: 871  PGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGP 930

Query: 1267 DAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGV 1326
               +G    D   G       QGIA +    G+  +   +G      + G + E   QG 
Sbjct: 931  AGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPG---LPGPSGEPGKQGP 987

Query: 1327 AHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAA 1386
            +     +G        G+A      G      A+     D + G   +    G A    A
Sbjct: 988  SGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGA 1047

Query: 1387 QGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANE 1446
             G        G A +   +G        G       +G A      G   E    G    
Sbjct: 1048 PGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGI 1107

Query: 1447 DAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKP 1500
               +G +      G       QG +      G      + G   +D  + +  P
Sbjct: 1108 KGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGP 1161



 Score =  104 bits (260), Expect = 9e-22
 Identities = 168/807 (20%), Positives = 223/807 (27%), Gaps = 29/807 (3%)

Query: 67   GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126
            G+  E    G      A+G      A G        G      A G   E   QG    +
Sbjct: 305  GLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSE 364

Query: 127  AVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIA 186
              QGV  E    G A      G    D   G    + A GIA              Q   
Sbjct: 365  GPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPG 424

Query: 187  NEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQ---GVANEDPVQGVANEDAVQGVANEV 243
                 +G S E    G   +  A+G      VQ   G A E+  +G   E    G+    
Sbjct: 425  GPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPP 484

Query: 244  EVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIA 303
              +G       +G    D   G        G       +G   E    G A     +G+ 
Sbjct: 485  GERG---GPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLT 541

Query: 304  NEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAH 363
                  G   +    G A +D       P  A G   +    G      A G   +    
Sbjct: 542  GSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARG---QAGVMGFPGPKGAAGEPGKAGER 598

Query: 364  GVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANE 423
            GV     A G A +D   G        G  A E   Q  A      G+       G A +
Sbjct: 599  GVPGPPGAVGPAGKDGEAGAQGPPGPAG-PAGERGEQGPAGSPGFQGLPGPAGPPGEAGK 657

Query: 424  DAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGV 483
               QG+  ++ A G S     +G   E   QG        G A      G    D   G 
Sbjct: 658  PGEQGVPGDLGAPGPSGARGERGFPGERGVQG------PPGPAGPRGANGAPGNDGAKGD 711

Query: 484  AKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAA 543
            A    A G         +     A G+      +G A    ADG   +D V G+   +  
Sbjct: 712  AGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGP 771

Query: 544  HGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIE 603
             G A        + P    G A     +G      A G   E    G A      G   +
Sbjct: 772  PGPAGAPGDKGESGPS---GPAGPTGARG------APGDRGEPGPPGPAGFAGPPGADGQ 822

Query: 604  DAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQA 663
               +G   +    G A      G A      G       +G        G      AA  
Sbjct: 823  PGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGR 882

Query: 664  IAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDA 723
            +  P  + G A      G A ++  +G   E    G   EV   G       +G    D 
Sbjct: 883  VGPPGPS-GNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADG 941

Query: 724  AQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAH 783
              G       QGIA +  V G+  +    G      + G + E   QG +     +G   
Sbjct: 942  PAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPG---LPGPSGEPGKQGPSGASGERGPPG 998

Query: 784  EDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQG 843
                 G+A      G      A G    D + G   +    G A      G        G
Sbjct: 999  PMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVG 1058

Query: 844  VAKEVTAHGVTNEDAVQGVVNEEALHG 870
             A +    G T      G V      G
Sbjct: 1059 PAGKSGDRGETGPAGPAGPVGPVGARG 1085



 Score =  101 bits (252), Expect = 8e-21
 Identities = 199/1033 (19%), Positives = 269/1033 (26%), Gaps = 63/1033 (6%)

Query: 1221 PDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQG 1280
            P   RG+     A G        G   E  A G        G   ++   G A +    G
Sbjct: 183  PSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPG 242

Query: 1281 IAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDA 1340
                   QG        G+      +G +  D  +G A     +G        G   +  
Sbjct: 243  ERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMG 302

Query: 1341 AHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVAN 1400
              G+  E    G      A+     D A G +      G A      G            
Sbjct: 303  PRGLPGERGRPGAPGPAGAR---GNDGATGAAGPPGPTGPAGPPGFPGAV---------- 349

Query: 1401 EDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQG 1460
                 G   E   QG    +  QG+  E    G A      G    D   G    + A G
Sbjct: 350  -----GAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPG 404

Query: 1461 IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDV 1520
            IA      G        G        G + E  A        A+G    V  QG      
Sbjct: 405  IAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQG------ 458

Query: 1521 ADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVN 1580
              G A E+   G   E    G+       G        G        G A E    G   
Sbjct: 459  PPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAG 518

Query: 1581 EDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAH 1640
                      E      A    A G+     +     K    G A QD   G      A 
Sbjct: 519  PKGS----PGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGAR 574

Query: 1641 GISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANED 1700
            G   +  V G      A G   +   +G+       G A +D   G        G A E 
Sbjct: 575  G---QAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGER 631

Query: 1701 PVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIA 1760
              QG A     QG+       G A +   QG+  +  A G +      G   E   QG  
Sbjct: 632  GEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPP 691

Query: 1761 HEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVAD 1820
                 +G               A+G    D A   A    A G       QG+  E  A 
Sbjct: 692  GPAGPRG---------------ANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAA 736

Query: 1821 GIPNEDAAHGVANEVAAHGISKEDAVQGIA------NEDAAQGIAKEDPIQGVANEVEVQ 1874
            G+P      G A    A G   +D V+G+           A G   E    G A     +
Sbjct: 737  GLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGAR 796

Query: 1875 GV---AHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIA 1931
            G      E    G A      G   +  A+G   +  A+  A      G +      G  
Sbjct: 797  GAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNV 856

Query: 1932 NQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQ 1991
                A+G        G      A G        G A      G A ++  +G   E    
Sbjct: 857  GAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPA 916

Query: 1992 GIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANED 2051
            G   E    G             D   G       QGIA +    G+  +    G     
Sbjct: 917  GRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLP 976

Query: 2052 AAQAIAKPDAAHGIANE-----GIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGIT 2106
                        G + E      +    +A    E   +G    E +     +D + G  
Sbjct: 977  GPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPG---RDGSPGAK 1033

Query: 2107 KEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQ 2166
             +    G      A G        G A +    G        G    V A+G A     +
Sbjct: 1034 GDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPR 1093

Query: 2167 GVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANED 2226
            G   E   QG       +G +      G        G +      G      + G   +D
Sbjct: 1094 GDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKD 1153

Query: 2227 AAQGVANEVAVHG 2239
               G+   +   G
Sbjct: 1154 GLNGLPGPIGPPG 1166



 Score =  101 bits (252), Expect = 8e-21
 Identities = 186/923 (20%), Positives = 244/923 (26%), Gaps = 33/923 (3%)

Query: 406  DAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGI 465
            D A G A      G        G   ++   G+  E    G      A+G    D A G 
Sbjct: 274  DGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARG---NDGATGA 330

Query: 466  AHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVA 525
            A      G A      G    V A G A          P   RG   E    G A     
Sbjct: 331  AGPPGPTGPAGPPGFPGA---VGAKGEAGPQGPRGSEGPQGVRG---EPGPPGPAGAAGP 384

Query: 526  DGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANE 585
             G    D   G      A G+A          P    G       +G + E  A G   +
Sbjct: 385  AGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGD 444

Query: 586  DAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGV 645
              A G    V V G        G A E+   G   E    G+       G   E    G 
Sbjct: 445  TGAKGEPGPVGVQGPP------GPAGEEGKRGARGEPGPTGLP------GPPGERGGPGS 492

Query: 646  VNEDALHGVVANEDAAQAIAKPDAA--HGIANEVAAHGIANEDAAQGIANEDAAQGIANE 703
                   GV   +  A     P  A   G   E    G A    A+G+     + G   +
Sbjct: 493  RGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGK 552

Query: 704  VAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGV 763
                G + +D   G      A+G A    V G        G   +    GV       G 
Sbjct: 553  TGPPGPAGQDGRPGPPGPPGARGQA---GVMGFPGPKGAAGEPGKAGERGVPGPPGAVGP 609

Query: 764  ANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAA 823
            A +D   G        G A E   QG A      G+       G A +   QGV  +  A
Sbjct: 610  AGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGA 669

Query: 824  QGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAK 883
             G +      G   E   QG        G        G   +    G   ++ A      
Sbjct: 670  PGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGM 729

Query: 884  PDAAHGIANEGVANEVAAQGIATEDVADGI-AKDAAHGITKEEAAQAIAKQDAAHSITNE 942
            P    G A  G+      +G A    ADG   KD   G+T        A        +  
Sbjct: 730  P-GERGAA--GLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGP 786

Query: 943  DAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGI 1002
                G      A G   E    G A      G   +    G   +   +G A      G 
Sbjct: 787  SGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGP 846

Query: 1003 AHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAV 1062
            A      G      A G        G      A G        G A      G + ++  
Sbjct: 847  AGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGG 906

Query: 1063 QGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANE 1122
            +G   E    G   E    G       +G    D   G        G+A +  V G+  +
Sbjct: 907  KGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQ 966

Query: 1123 DAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGI 1182
               +G      + G + E   QG +      G    +   G+A      G      A+G 
Sbjct: 967  RGERGFPG---LPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGS 1023

Query: 1183 AHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVA 1242
               D   G   +    G A    A G          A     RG        G      A
Sbjct: 1024 PGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGA 1083

Query: 1243 DGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKE 1302
             G A      G   E    G       +G +      G       QG +      G    
Sbjct: 1084 RGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGP 1143

Query: 1303 DPVQGVANEDPIQGVANEVEVQG 1325
                G   +D + G+   +   G
Sbjct: 1144 PGSAGAPGKDGLNGLPGPIGPPG 1166



 Score =  101 bits (252), Expect = 8e-21
 Identities = 187/884 (21%), Positives = 241/884 (27%), Gaps = 61/884 (6%)

Query: 956  GVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANED 1015
            G    D A G A      G A      G        G   E   QG    +  QG+  E 
Sbjct: 320  GARGNDGATGAAGPPGPTGPAGPPGFPGAV------GAKGEAGPQGPRGSEGPQGVRGEP 373

Query: 1016 AAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIA 1075
               G A      G    D   G    + A GIA      G       QG       +G +
Sbjct: 374  GPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNS 433

Query: 1076 NEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQ 1135
             E  A G   +   +G      V G        G A E+  +G   E    G+      +
Sbjct: 434  GEPGAPGSKGDTGAKGEPGPVGVQGPP------GPAGEEGKRGARGEPGPTGLPGPPGER 487

Query: 1136 GVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 1195
            G        G        G A E  + G A    + G A      G+      +G+    
Sbjct: 488  GGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLP---GAKGLTGSP 544

Query: 1196 AVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVA 1255
               G   +    G A +D       P  ARG A  +   G        G A E    G  
Sbjct: 545  GSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPP 604

Query: 1256 NEVAAHGISKEDAVQGI------ANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVA 1309
              V   G   E   QG       A E   QG A     QG+       G A +   QGV 
Sbjct: 605  GAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVP 664

Query: 1310 NEDPIQGVANEVEVQGVAHEDAVQGI---ANEDAAHGIANEDAAQGIANEDAAQDIANED 1366
             +    G +     +G   E  VQG    A    A+G    D A+G A    A       
Sbjct: 665  GDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAP 724

Query: 1367 AAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIA 1426
              QG+  E    G+      +G A      G   +D V+G+   +   G A      G  
Sbjct: 725  GLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPA---GAPGDK 781

Query: 1427 NEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAH 1486
             E    G A    A G      A G   E    G A      G   +    G   +  A 
Sbjct: 782  GESGPSGPAGPTGARG------APGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAK 835

Query: 1487 GVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEV 1546
            G A        A P    G       +G        G      A G        G A   
Sbjct: 836  GDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPP 895

Query: 1547 AVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGI 1606
               G A ++  +G   E    G   E    G           A E  +     P  A G 
Sbjct: 896  GPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGP-------AGEKGSPGADGPAGAPG- 947

Query: 1607 ANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAA 1666
                           QGIA Q    G+  +    G      + G + E   QG +     
Sbjct: 948  -----------TPGPQGIAGQRGVVGLPGQRGERGF---PGLPGPSGEPGKQGPSGASGE 993

Query: 1667 QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHE 1726
            +G        G+A      G      A G    D   G   +    G A      G    
Sbjct: 994  RGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGA 1053

Query: 1727 DAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGV 1786
                G A +    G T      G      A+G A     +G   E        E    G+
Sbjct: 1054 PGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETG------EQGDRGI 1107

Query: 1787 ANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHG 1830
                    +  P    G   E    G +      G P    A G
Sbjct: 1108 KGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPG 1151



 Score = 98.6 bits (244), Expect = 6e-20
 Identities = 191/952 (20%), Positives = 258/952 (27%), Gaps = 75/952 (7%)

Query: 608  GVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKP 667
            G   +D   G       +G      A G+     + G+       G+    D A+  A P
Sbjct: 227  GKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGL----DGAKGDAGP 282

Query: 668  DAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGI 727
                G       +G   +   +G+  E    G      A G    D   G A      G 
Sbjct: 283  AGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARG---NDGATGAAGPPGPTGP 339

Query: 728  AHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAV 787
            A      G        G   E    G    +  QGV  E    G A      G    D  
Sbjct: 340  AGPPGFPGAV------GAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQ 393

Query: 788  QGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKE 847
             G    + A GIA      G       QG       +G + E    G   +  A+G    
Sbjct: 394  PGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGP 453

Query: 848  VTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATE 907
            V   G        G   EE   G             P    G  + G             
Sbjct: 454  VGVQGPP------GPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPG---------- 497

Query: 908  DVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVA 967
              ADG+A     G   E  +   A              +G   E    G A    A+G+ 
Sbjct: 498  --ADGVA--GPKGPAGERGSPGPA------------GPKGSPGEAGRPGEAGLPGAKGLT 541

Query: 968  NEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAH 1027
                + G   +    G A +D   G       +G A    + G      A G   +    
Sbjct: 542  GSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQA---GVMGFPGPKGAAGEPGKAGER 598

Query: 1028 GIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHED 1087
            G+     A G A +D   G        G + E   QG A     QG+       G A + 
Sbjct: 599  GVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKP 658

Query: 1088 AVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIA 1147
              QG+  +    G +      G   E  VQG       +G        G    D  +G A
Sbjct: 659  GEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGA------NGAPGNDGAKGDA 712

Query: 1148 NEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAH 1207
                A G        G+  E  A G+      +G A      G   +D V G+   +   
Sbjct: 713  GAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPP 772

Query: 1208 GVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKED 1267
            G A        + P    G A    A+G      A G   E    G A      G   + 
Sbjct: 773  GPAGAPGDKGESGPS---GPAGPTGARG------APGDRGEPGPPGPAGFAGPPGADGQP 823

Query: 1268 AVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVA 1327
              +G   +  A+G A      G A      G       +G        G        G  
Sbjct: 824  GAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRV 883

Query: 1328 HEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQ 1387
                  G A      G A ++  +G   E        E    G        G A E  + 
Sbjct: 884  GPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPG------PPGPAGEKGSP 937

Query: 1388 GIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANED 1447
            G    D   G       QG+A +  V G+  +   +G        G   +    G + E 
Sbjct: 938  GA---DGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGER 994

Query: 1448 AAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIA 1507
               G        G   E   +G    +   G      A G   E      A P  A G  
Sbjct: 995  GPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGP---AGPPGAPGAP 1051

Query: 1508 NEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQG 1559
                  G A +    G        G    V A+G A      G   E   QG
Sbjct: 1052 GAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQG 1103



 Score = 98.2 bits (243), Expect = 8e-20
 Identities = 206/1038 (19%), Positives = 278/1038 (26%), Gaps = 61/1038 (5%)

Query: 75   QGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANE 134
            +G+     A G        G   E  A G        G   +    G A +    G    
Sbjct: 187  RGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGP 246

Query: 135  DAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQGI 194
               QG        G+       G +  D A+G A     +             +   +G+
Sbjct: 247  PGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGL 306

Query: 195  SKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVAN---EVEVQGVAHE 251
              E    G      A+G    D   G A      G A      G      E   QG    
Sbjct: 307  PGERGRPGAPGPAGARG---NDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGS 363

Query: 252  DAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 311
            +  QG+  E    G        G    D   G    + A GIA      G        G 
Sbjct: 364  EGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGP 423

Query: 312  AKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKEVTA 371
                   G + E  A        A G    V  QG        G A E+   G   E   
Sbjct: 424  GGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQG------PPGPAGEEGKRGARGEPGP 477

Query: 372  HGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIAN 431
             G+      +G        G       A  +A P    G A E  + G A    + G A 
Sbjct: 478  TGLPGPPGERGGPGSRGFPG-------ADGVAGPK---GPAGERGSPGPAGPKGSPGEAG 527

Query: 432  EVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHG 491
                 G+      +G+     + G   +    G A +D   G        G A  +   G
Sbjct: 528  RPGEAGLP---GAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPG 584

Query: 492  VANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDA 551
               K AA    K    RG+     A G A +D   G        G A E    G A    
Sbjct: 585  P--KGAAGEPGKA-GERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPG 641

Query: 552  AHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVAN 611
               +  P    G A +   QG+  +  A G +      G   E  V G        G A 
Sbjct: 642  FQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPP------GPAG 695

Query: 612  EDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAH 671
                +G    D A+G A    A G      +QG+            E  A  +  P    
Sbjct: 696  PRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGM----------PGERGAAGLPGPKGDR 745

Query: 672  GIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHED 731
            G A    A G   +D  +G+       G A    A G   E    G A    A+G     
Sbjct: 746  GDAGPKGADGSPGKDGVRGLTGPIGPPGPAG---APGDKGESGPSGPAGPTGARG----- 797

Query: 732  AVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIA 791
               G   E    G A      G   +   +G   +   +G A      G A      G  
Sbjct: 798  -APGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNV 856

Query: 792  NEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAH 851
                A G        G      A G        G A      G A ++  +G   E    
Sbjct: 857  GAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPA 916

Query: 852  GVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVAD 911
            G   E    G        G    +  A A   P        +G+A +    G+  +    
Sbjct: 917  GRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGP------QGIAGQRGVVGLPGQRGER 970

Query: 912  GIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVA 971
            G       G + E   Q  +               G+A      G      A+G      
Sbjct: 971  GFP--GLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDG 1028

Query: 972  AQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIAN 1031
            + G   +    G A      G        G A K   +G        G    V A G A 
Sbjct: 1029 SPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAG 1088

Query: 1032 EDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQG 1091
                +G   E   QG        G S      G       QG +      G        G
Sbjct: 1089 PQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAG 1148

Query: 1092 IANEDAVHGVAKEVAAHG 1109
               +D ++G+   +   G
Sbjct: 1149 APGKDGLNGLPGPIGPPG 1166



 Score = 96.3 bits (238), Expect = 3e-19
 Identities = 160/766 (20%), Positives = 209/766 (27%), Gaps = 15/766 (1%)

Query: 65   AHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVAN 124
            A G   E   QG       QGV  E    G A      G    D   G      A G+A 
Sbjct: 348  AVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAG 407

Query: 125  EDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDI---AKEDA 181
                 G       QG       +G + E  A G   +  A+G       Q     A E+ 
Sbjct: 408  APGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEG 467

Query: 182  AQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVAN 241
             +    E    G+      +G      ++G    D V G       +G       +G   
Sbjct: 468  KRGARGEPGPTGLPGPPGERG---GPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPG 524

Query: 242  EVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQG 301
            E    G A     +G+     + G   +    G A +D   G      A+G A    V G
Sbjct: 525  EAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQA---GVMG 581

Query: 302  IANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDA 361
                    G   +    GV     A   A  D   G        G A E    G A    
Sbjct: 582  FPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPG 641

Query: 362  AHGVAKEVTAHGVANEDAVQGVVNEDALHGV--VANEDAAQAIAKPDAAHGIANEVAAHG 419
              G+       G A +   QGV  +    G      E             G A    A+G
Sbjct: 642  FQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANG 701

Query: 420  IANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDA 479
                D A+G A    A G      +QG+  E  A G+      +G A      G   +D 
Sbjct: 702  APGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDG 761

Query: 480  VHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVAN 539
            V G+   +   G A        + P    G      A G   E    G A      G   
Sbjct: 762  VRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADG 821

Query: 540  EVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHG 599
            +  A G   +  A   A P    G A      G      A G        G        G
Sbjct: 822  QPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAG 881

Query: 600  VAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANED 659
                    G A      G A ++  +G   E    G   E    G        G    + 
Sbjct: 882  RVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADG 941

Query: 660  AAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIA 719
             A A   P    GIA +    G+  +   +G        G   +    G S E    G  
Sbjct: 942  PAGAPGTP-GPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPM 1000

Query: 720  NEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQ 779
                  G   E   +G    +   G      A G   E    G        G    V   
Sbjct: 1001 GPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPV--- 1057

Query: 780  GIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQG 825
            G A +   +G        G    V A G A     +G   E   QG
Sbjct: 1058 GPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQG 1103



 Score = 92.8 bits (229), Expect = 4e-18
 Identities = 145/670 (21%), Positives = 192/670 (28%), Gaps = 40/670 (5%)

Query: 1619 DAAQGIANQDAAQGIANEVA---AHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAV 1675
            D A G A      G A       A G   E   QG    +  QG+  E    G A     
Sbjct: 325  DGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGP 384

Query: 1676 QGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANE 1735
             G    D   G      A G+A      G       QG       +G + E    G   +
Sbjct: 385  AGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGD 444

Query: 1736 DAAHGITNEVAAHGI---ANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAA 1792
              A G    V   G    A E+  +G   E    G+           E    G      A
Sbjct: 445  TGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPG------ERGGPGSRGFPGA 498

Query: 1793 HAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANE 1852
              +A P   +G A E  + G A      G P E    G A    A G++      G   +
Sbjct: 499  DGVAGP---KGPAGERGSPGPAGPK---GSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGK 552

Query: 1853 DAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDI 1912
                G A +D   G       +G A    V G      A G   +   +G+     A   
Sbjct: 553  TGPPGPAGQDGRPGPPGPPGARGQA---GVMGFPGPKGAAGEPGKAGERGVPGPPGAVGP 609

Query: 1913 ANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAA 1972
            A +D   G        G A +   QG A     QG+       G A +    G+  +  A
Sbjct: 610  AGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGA 669

Query: 1973 QGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATE 2032
             G +     +G   E  VQG        G A    A+     D A+G A    A G    
Sbjct: 670  PGPSGARGERGFPGERGVQGPP------GPAGPRGANGAPGNDGAKGDAGAPGAPGSQGA 723

Query: 2033 DVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEA 2092
                G+  E  A G+      +  A P  A G   +             D V+G+T    
Sbjct: 724  PGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGK-------------DGVRGLTGPIG 770

Query: 2093 AQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVAN 2152
                A      G +      G T    A G   E    G A      G   +  A+G   
Sbjct: 771  PPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPG 830

Query: 2153 EVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQG 2212
            +  A+G A      G A      G       +G        G      A G        G
Sbjct: 831  DAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSG 890

Query: 2213 VANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDA 2272
             A      G A ++  +G   E    G   E            +G    D   G      
Sbjct: 891  NAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPG 950

Query: 2273 VHGIANEDAV 2282
              GIA +  V
Sbjct: 951  PQGIAGQRGV 960



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 174/872 (19%), Positives = 237/872 (27%), Gaps = 58/872 (6%)

Query: 1415 GVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 1474
            G       QG   E    G +  +   G        G   E    G   E    G     
Sbjct: 194  GAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGAR 253

Query: 1475 AVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVA 1534
             + G A      G+         +  D A+G A     +G       +G   +    G+ 
Sbjct: 254  GLPGTA------GLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLP 307

Query: 1535 NEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNE--DALHSVVANED 1592
             E    G        G    D   G        G A      G V    +A        +
Sbjct: 308  GERGRPGAPGPAGARG---NDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSE 364

Query: 1593 AAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIA 1652
              Q +       G A           D   G    + A GIA      G       QG  
Sbjct: 365  GPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPG 424

Query: 1653 NEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV---AKEVAAHGVANEDPVQGVANED 1709
                 +G + E  A G   +   +G      V G    A E    G   E    G+    
Sbjct: 425  GPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPP 484

Query: 1710 AVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIA 1769
              +G       +G    D V G        G        G   E    G A     +G+ 
Sbjct: 485  GERGGPGS---RGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLT 541

Query: 1770 NEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVA------AQGIATEDVADGIP 1823
                      +    G A +D       P  ARG A  +       A G   +    G+P
Sbjct: 542  GSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVP 601

Query: 1824 NEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQ 1883
                A G A +    G        G A E   QG A     QG+       G A +   Q
Sbjct: 602  GPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQ 661

Query: 1884 GIANEDAAHGIANEDAAQGIANEDAAQDI---ANEDAAQGISKEDAVQGIANQDAAQGIA 1940
            G+  +  A G +     +G   E   Q     A    A G    D  +G A    A G  
Sbjct: 662  GVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQ 721

Query: 1941 KEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVH 2000
                +QG+  E  A G+       G A    A G   +D  +G+       G A      
Sbjct: 722  GAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDK 781

Query: 2001 GVANEDAAHAIAKPDAARGIANE------VAAQGIATEDVADGIANEDAAHGVANEDAAQ 2054
            G   E      A P  ARG   +          G A    ADG   +  A G   +  A+
Sbjct: 782  G---ESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADG---QPGAKGEPGDAGAK 835

Query: 2055 AIAKPDAAHG-------IANEGIATEDVADGIAED-------AVQGITNEEAAQAIAKQD 2100
              A P    G       I N G      A G A            G          A   
Sbjct: 836  GDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPP 895

Query: 2101 AAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVA 2160
               G   ++  +G   E    G   E    G        G    D   G       QG+A
Sbjct: 896  GPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIA 955

Query: 2161 NEDAVQGVANEVEVQGI------AHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVA 2214
             +  V G+  +   +G       + +   QG +     +G    +   G+A      G  
Sbjct: 956  GQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGRE 1015

Query: 2215 NEVAAQGVANEDAAQGVANEVAVHGVANEDAA 2246
                A+G    D + G   +    G A    A
Sbjct: 1016 GAPGAEGSPGRDGSPGAKGDRGETGPAGPPGA 1047



 Score = 89.7 bits (221), Expect = 3e-17
 Identities = 153/786 (19%), Positives = 215/786 (27%), Gaps = 47/786 (5%)

Query: 1500 PDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQG 1559
            P  ARG+       G+       G +  D A G A     +G       +G   +   +G
Sbjct: 249  PQGARGLPGTAGLPGMKGHR---GFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRG 305

Query: 1560 VVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVA---AHSIA 1616
            +  E    G       +G              D A   A P    G A       A    
Sbjct: 306  LPGERGRPGAPGPAGARG-------------NDGATGAAGPPGPTGPAGPPGFPGAVGAK 352

Query: 1617 NKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQ 1676
             +   QG    +  QG+  E    G +      G    D   G    + A GIA      
Sbjct: 353  GEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFP 412

Query: 1677 GIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGV---AHEDAVQGIA 1733
            G        G        G + E    G   +   +G    V VQG    A E+  +G  
Sbjct: 413  GARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGAR 472

Query: 1734 NEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAH 1793
             E    G+       G      ++G    D V G                 G   E    
Sbjct: 473  GEPGPTGLPGPPGERG---GPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRP 529

Query: 1794 AIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANED 1853
              A    A+G+     + G   +    G   +D   G      A G   +  V G     
Sbjct: 530  GEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARG---QAGVMGFPGPK 586

Query: 1854 AAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIA 1913
             A G   +   +GV       G A +D   G        G A E   QG A     Q + 
Sbjct: 587  GAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLP 646

Query: 1914 NEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQ 1973
                  G + +   QG+     A G +     +G   E   QG        G A    A 
Sbjct: 647  GPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQG------PPGPAGPRGAN 700

Query: 1974 GIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATED 2033
            G    D A+G A      G      + G+  E  A  +  P   RG A    A G   +D
Sbjct: 701  GAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKD 760

Query: 2034 VADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAA 2093
               G+       G A     +  + P    G      A  D          +G       
Sbjct: 761  GVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGD----------RGEPGPPGP 810

Query: 2094 QAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANE 2153
               A    A G   +  A+G   +  A+G A      G A      G      A+G    
Sbjct: 811  AGFAGPPGADG---QPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGS 867

Query: 2154 VAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGV 2213
                G        G        G A      G A ++  +G   E    G   E    G 
Sbjct: 868  AGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGP 927

Query: 2214 ANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAV 2273
                  +G    D   G        G+A +     +  +   +G        G   +   
Sbjct: 928  PGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGP 987

Query: 2274 HGIANE 2279
             G + E
Sbjct: 988  SGASGE 993



 Score = 79.0 bits (193), Expect = 5e-14
 Identities = 113/504 (22%), Positives = 147/504 (29%), Gaps = 32/504 (6%)

Query: 1802 RGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKE 1861
            RG +    A+G A      G P     +G   ++   G+  E    G      A+G    
Sbjct: 268  RGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGA 327

Query: 1862 DPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGI 1921
                G        G        G   E    G    +  QG+  E      A      G 
Sbjct: 328  TGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGN 387

Query: 1922 SKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAA 1981
               D   G    + A GIA      G       QG        G + E  A G   +  A
Sbjct: 388  PGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGA 447

Query: 1982 QGIAHEDAVQGI---ANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGI 2038
            +G      VQG    A E+   G   E     +  P   RG        G      ADG+
Sbjct: 448  KGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPG------ADGV 501

Query: 2039 ANEDAAHGVANEDAAQAIAKPDAAHGIANE-GIATEDVADGIA-EDAVQGITNEEAAQAI 2096
            A      G A E  +   A P  + G A   G A    A G+       G   +      
Sbjct: 502  AGPK---GPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGP 558

Query: 2097 AKQDAAHGITKEDAAQGVTNEVA------AQGVANEDAAHGVANEVAAHGVANEDAAQGV 2150
            A QD   G      A+G    +       A G   +    GV     A G A +D   G 
Sbjct: 559  AGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGA 618

Query: 2151 ANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAA 2210
                   G A E   QG A     QG+       G A +   QGV  ++ A G +     
Sbjct: 619  QGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGE 678

Query: 2211 QGVANEVAAQ------------GVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGI 2258
            +G   E   Q            G    D A+G A      G       + M  E  A G+
Sbjct: 679  RGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGL 738

Query: 2259 ANEDAAHGIANEDAVHGIANEDAV 2282
                   G A      G   +D V
Sbjct: 739  PGPKGDRGDAGPKGADGSPGKDGV 762



 Score = 75.9 bits (185), Expect = 4e-13
 Identities = 135/663 (20%), Positives = 182/663 (27%), Gaps = 45/663 (6%)

Query: 1649 QGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANE 1708
            +G+     A G        G   E    G        G   +    G A +    G    
Sbjct: 187  RGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGP 246

Query: 1709 DAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGI 1768
               QG        G+      +G +  D A G        G        G   +   +G+
Sbjct: 247  PGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGL 306

Query: 1769 ANEDAVHSVAKEVAAHGVANEDAAHAIAKPD-----------AARGIANEVAAQGIATED 1817
              E           A G  N+ A  A   P             A G   E   QG    +
Sbjct: 307  PGERGRPGAPGPAGARG--NDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSE 364

Query: 1818 VADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVA 1877
               G+  E    G A      G    D   G    + A GIA      G       QG  
Sbjct: 365  GPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPG 424

Query: 1878 HEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDI---ANEDAAQGISKEDAVQGIANQD 1934
                 +G + E  A G   +  A+G       Q     A E+  +G   E    G+    
Sbjct: 425  GPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPP 484

Query: 1935 A------AQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHED 1988
                   ++G    D V G       +G        G   E    G A    A+G+    
Sbjct: 485  GERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSP 544

Query: 1989 AVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVA------AQGIATEDVADGIANED 2042
               G   +    G A +D       P  ARG A  +       A G   +    G+    
Sbjct: 545  GSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPP 604

Query: 2043 AAHGVANEDAAQAIAKPDAAHGIANE----GIATEDVADGIAEDA----------VQGIT 2088
             A G A +D       P    G A E    G A      G+   A           QG+ 
Sbjct: 605  GAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVP 664

Query: 2089 NEEAAQAIAKQDAAHGITKEDAAQGVTNEVA---AQGVANEDAAHGVANEVAAHGVANED 2145
             +  A   +      G   E   QG         A G    D A G A    A G     
Sbjct: 665  GDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAP 724

Query: 2146 AAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVA 2205
              QG+  E  A G+      +G A      G   KD ++G+       G A      G +
Sbjct: 725  GLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGES 784

Query: 2206 NEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAH 2265
                  G      A G   E    G A      G   +  A+    +  A+G A      
Sbjct: 785  GPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPA 844

Query: 2266 GIA 2268
            G A
Sbjct: 845  GPA 847


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score =  100 bits (248), Expect = 2e-20
 Identities = 211/1047 (20%), Positives = 282/1047 (26%), Gaps = 56/1047 (5%)

Query: 65   AHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVAN 124
            A G       QG A E    G      A G A      G A ED   G       +GV  
Sbjct: 104  AAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPP---GKAGEDGHPGKPGRPGERGVVG 160

Query: 125  EDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQD 184
                +G      + G       +GI   +   G+  +  A G+  E  A           
Sbjct: 161  PQGARGFPGTPGLPG------FKGIRGHNGLDGLKGQPGAPGVKGEPGA------PGENG 208

Query: 185  IANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVE 244
               +  A+G+  E    G      A+G        G A      G        G   E+ 
Sbjct: 209  TPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIG 268

Query: 245  VQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIAN 304
              G A      G   E    G++  V   G    +   G        G+A    + G   
Sbjct: 269  AVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRG 328

Query: 305  EDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHG 364
                 G A    A G+  E        P  + G +      G A      G + E+   G
Sbjct: 329  IPGPVGAAGATGARGLVGEPG------PAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRG 382

Query: 365  VAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANED 424
               E  + G      ++G      L G     D    +  P  + G +      G   + 
Sbjct: 383  PNGEAGSAGPPGPPGLRGSPGSRGLPGA----DGRAGVMGPPGSRGASGPAGVRGPNGDA 438

Query: 425  AAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVA 484
               G    +   G+       G A ++   G+   D   G       +G        G  
Sbjct: 439  GRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPK 498

Query: 485  KEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAH 544
                  G  N D  HA        G+A    A G    + A G      V G   E    
Sbjct: 499  GPTGDPG-KNGDKGHA--------GLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPP 549

Query: 545  GVAN-------EDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAV 597
            G             A  + KP    G+  E    G A      G   E  A G    +  
Sbjct: 550  GPPGFQGLPGPSGPAGEVGKP-GERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGS 608

Query: 598  HGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVAN 657
             G +      G   E  V G        G +      G A     +G   E  L G + N
Sbjct: 609  RGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGN 668

Query: 658  EDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQG 717
                 A   P A  G      A G   E  A G A     +G   E    G +  +   G
Sbjct: 669  PGRDGARGAPGAV-GAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAG 727

Query: 718  IANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVA---NEDVVQGVAN 774
             A      G   E   +G   E+ V G    V A G A  +   G A    +    G+  
Sbjct: 728  PAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTG 787

Query: 775  EVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAA---QGVANEDA 831
                 G        GI+      G A +    G   +    G   E  A    G A E  
Sbjct: 788  FPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKG 847

Query: 832  VHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGV--VANEDAAQAIAKPDAAHG 889
              G A      G        G      + G   E  L GV     E     IA P  A G
Sbjct: 848  PSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARG 907

Query: 890  ----IANEGVANEVAAQGIATEDVADG-IAKDAAHGITKEEAAQAIAKQDAAHSITNEDA 944
                + + GV       G       DG   +D   G   E           A        
Sbjct: 908  PPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHG 967

Query: 945  AQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAH 1004
              G A +    G        G A  V  +G +    + G   E   +G      ++G   
Sbjct: 968  PVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNG 1027

Query: 1005 KDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQG 1064
               + GIA      G    V   G        G A +D   G    V   GI      QG
Sbjct: 1028 LQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQG 1087

Query: 1065 IANEDAAQGIANEDAAQGIAHEDAVQG 1091
             A      G        G  ++    G
Sbjct: 1088 PAGPPGPPGPPGPPGVSGGGYDFGYDG 1114



 Score = 99.8 bits (247), Expect = 3e-20
 Identities = 218/1086 (20%), Positives = 288/1086 (26%), Gaps = 68/1086 (6%)

Query: 76   GVANEVAAQ----GVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGV 131
            G+    AAQ    GV       G+       G A     QG        G   +    G 
Sbjct: 72   GLGGNFAAQYDGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGA 131

Query: 132  ANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAA 191
                   G A ED   G        G+     A+G                + I   +  
Sbjct: 132  RGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGF------KGIRGHNGL 185

Query: 192  QGISKEDAVQGIANEDAA---QGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGV 248
             G+  +    G+  E  A    G   +   +G+  E    G       +G    V   G 
Sbjct: 186  DGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGP 245

Query: 249  AHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAV 308
            A      G      A G   E+ A G A      G   E    G++      G    + +
Sbjct: 246  AGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGL 305

Query: 309  HGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKE 368
             G        GVA               G A     +G+  E    G   E    G    
Sbjct: 306  TGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKG---- 361

Query: 369  VTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQG 428
                G A      G   E+   G   N +A    A P    G+     + G+   D   G
Sbjct: 362  --EPGSAGPQGPPGPSGEEGKRG--PNGEAGS--AGPPGPPGLRGSPGSRGLPGADGRAG 415

Query: 429  IANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVA 488
            +     + G S    V+G  N DA  G   E    G       +G+       G A +  
Sbjct: 416  VMGPPGSRGASGPAGVRG-PNGDA--GRPGEPGLMG------PRGLPGSPGNIGPAGKEG 466

Query: 489  AHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVAN 548
              G+   D       P  ARG    +   G       D   N D  H  A    A G   
Sbjct: 467  PVGLPGIDGRPGPIGPAGARGEPGNIGFPG-PKGPTGDPGKNGDKGH--AGLAGARGAPG 523

Query: 549  EDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQG 608
             D  +    P    G+      QG        G+       G   +    G+  E  + G
Sbjct: 524  PDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPG 583

Query: 609  VANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPD 668
             A      G   E  A G    + + G +      G   E  + G V         A P 
Sbjct: 584  PAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGT-------AGPS 636

Query: 669  AAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIA 728
               G+  E  A GI       G   E    G+  E+   G    D  +G      A G A
Sbjct: 637  GPSGLPGERGAAGI------PGGKGEKGEPGLRGEIGNPG---RDGARGAPGAVGAPGPA 687

Query: 729  HEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQ 788
                  G   E    G A      G   E    G A  +   G A      G   E   +
Sbjct: 688  ---GATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAK 744

Query: 789  GIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEV 848
            G   E+   G    V A G A  +   G A      G        G A      G +   
Sbjct: 745  GPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGIS 804

Query: 849  TAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATED 908
               G       +G+       G V       A+  P  A     +G + E    G     
Sbjct: 805  GPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFA---GEKGPSGEAGTAGPPGTP 861

Query: 909  VADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVAN 968
               G+    A GI     ++             E    G+A    A G      + GV  
Sbjct: 862  GPQGLL--GAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVN- 918

Query: 969  EVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHG 1028
               A G A  D   G        G       +G        G A     HG       HG
Sbjct: 919  --GAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHG 976

Query: 1029 IANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDA 1088
               E    G      A G        GI  +    G        G+   +  QG+     
Sbjct: 977  NRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGL----- 1031

Query: 1089 VQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIAN 1148
              GIA      G    V   G        G A +D   G    V   G+      QG A 
Sbjct: 1032 -PGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAG 1090

Query: 1149 EDAAHG 1154
                 G
Sbjct: 1091 PPGPPG 1096



 Score = 99.0 bits (245), Expect = 5e-20
 Identities = 218/1072 (20%), Positives = 294/1072 (27%), Gaps = 59/1072 (5%)

Query: 419  GIANEDAAQ----GIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGI 474
            G+    AAQ    G+       G+       G A     QG        G   +    G 
Sbjct: 72   GLGGNFAAQYDGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGA 131

Query: 475  ANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAV 534
                   G A E    G   +     +  P  ARG        G        GI   + +
Sbjct: 132  RGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFK------GIRGHNGL 185

Query: 535  HGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANE 594
             G+  +  A GV  E  A         +G   +   +G+  E    G      A G    
Sbjct: 186  DGLKGQPGAPGVKGEPGA------PGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGS 239

Query: 595  VAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGV 654
            V   G A      G        G   E  A G A      G A     +G V    L G 
Sbjct: 240  VGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNA------GPAGPAGPRGEVGLPGLSGP 293

Query: 655  VA--NEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQG---IANEDAAQGIANEVAAHGI 709
            V       A  +     A G+     A G+       G    A    A+G+  E    G 
Sbjct: 294  VGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGS 353

Query: 710  SKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVV 769
              E   +G       QG       +G    +   G A      G+      +G+   D  
Sbjct: 354  KGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGR 413

Query: 770  QGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANE 829
             GV      +G +    V+G   +    G    +   G+       G A ++   G+   
Sbjct: 414  AGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGI 473

Query: 830  DAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHG 889
            D   G      A+G    +   G        G   ++   G+      A+    PD  +G
Sbjct: 474  DGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAG----ARGAPGPDGNNG 529

Query: 890  IANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVA 949
               +G       QG   E    G       G+           +     +  E    G A
Sbjct: 530  A--QGPPGPQGVQGGKGEQGPPG--PPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPA 585

Query: 950  NEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQ 1009
                  G   E  A G    + ++G +      G   E  V G        G A      
Sbjct: 586  GPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAV------GTAGPSGPS 639

Query: 1010 GIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANED 1069
            G+  E  A GI       G        G    D A+G    V A G +      G   E 
Sbjct: 640  GLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPA---GATGDRGEA 696

Query: 1070 AAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVA 1129
             A G A     +G   E    G A  +   G A      G   E   +G   E+ V G  
Sbjct: 697  GAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPT 756

Query: 1130 NEVEVQGVAHEDAVQGIAN---EDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHED 1186
              V   G A  +   G A    +    G+     A G        GI+      G A ++
Sbjct: 757  GPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKE 816

Query: 1187 AVQGIANEDAVHGVAKEVAA---HGVANEDAAHA---IAKPDAARGIANEVAAQGIATED 1240
             ++G   +    G   EV A    G A E         A P    G    + A GI    
Sbjct: 817  GLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILG-- 874

Query: 1241 VADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIA 1300
               G   E    GVA  V   G        G      A G    +   G A  D   G  
Sbjct: 875  -LPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGND 933

Query: 1301 KEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQ 1360
                  G       +G    +   G A      G       HG   E    G      A 
Sbjct: 934  GPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAV 993

Query: 1361 DIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQG---VANEDAVQGVANEVEVQGVA 1417
                    QGI  +    G        G+   + +QG   +A     QG    V   G  
Sbjct: 994  GPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPR 1053

Query: 1418 HEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQG 1469
                  G A +D   G    V   GI      QG A      G      V G
Sbjct: 1054 GPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSG 1105



 Score = 97.4 bits (241), Expect = 1e-19
 Identities = 197/1031 (19%), Positives = 278/1031 (26%), Gaps = 62/1031 (6%)

Query: 1208 GVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKED 1267
            G A E        P  ARG A      G A ED   G        GV     A G     
Sbjct: 115  GPAGEPGEPGQTGPAGARGPAGP---PGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTP 171

Query: 1268 AVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVA 1327
             + G       +GI   + + G+  +  A G+  E    G        G   +   +G+ 
Sbjct: 172  GLPGF------KGIRGHNGLDGLKGQPGAPGVKGEPGAPGE------NGTPGQTGARGLP 219

Query: 1328 HEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQ 1387
             E    G      A G        G A    +        A G   E    G A      
Sbjct: 220  GERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPA 279

Query: 1388 GIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANED 1447
            G   E  + G++      G      + G      + G+A      G        G A   
Sbjct: 280  GPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGAT 339

Query: 1448 AAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIA 1507
             A+G+  E    G   E   +G        G        G    +     A P    G+ 
Sbjct: 340  GARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLR 399

Query: 1508 NEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAH 1567
                ++G+   D   G+     + G +     +G   +    G       +G+       
Sbjct: 400  GSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNI 459

Query: 1568 GVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQ 1627
            G A ++   G+   D     +     A A  +P    G            K+  +G A  
Sbjct: 460  GPAGKEGPVGLPGIDGRPGPIG---PAGARGEPGNI-GFPGPKGPTGDPGKNGDKGHAGL 515

Query: 1628 DAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1687
              A+G       +G       QG+      QG       QG+       G   +    G+
Sbjct: 516  AGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGL 575

Query: 1688 AKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAA 1747
              E    G A     +G   E    G    +  +G +      G   E    G       
Sbjct: 576  HGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGP 635

Query: 1748 HGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANE 1807
             G +     +G A     +G   E  +          G      A     P  A G   E
Sbjct: 636  SGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGE 695

Query: 1808 VAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGV 1867
              A G A      G P E    G A      G +      G   E  A+G   E+ + G 
Sbjct: 696  AGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGP 755

Query: 1868 ANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAV 1927
               V   G A  +   G A      G   +    G+     A          GIS     
Sbjct: 756  TGPVGAAGPAGPNGPPGPA------GSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGP 809

Query: 1928 QGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHE 1987
             G A ++  +G   +    G   E  A G        G + E    G       QG+   
Sbjct: 810  PGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGA 869

Query: 1988 DAVQGIANE------DAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANE 2041
              + G+           V G   E     IA P  ARG    V + G+   + A G A  
Sbjct: 870  PGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGV---NGAPGEAGR 926

Query: 2042 DAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQDA 2101
            D   G                    N+G    D   G      +G          A    
Sbjct: 927  DGNPG--------------------NDGPPGRDGQPG--HKGERGYPGNIGPVGAAGAPG 964

Query: 2102 AHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVAN 2161
             HG        G   E    G      A G        G+  +    G        G+  
Sbjct: 965  PHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKG 1024

Query: 2162 EDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQG 2221
             + +QG      + GIA     QG        G        G A +D   G    V   G
Sbjct: 1025 HNGLQG------LPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAG 1078

Query: 2222 VANEDAAQGVA 2232
            +      QG A
Sbjct: 1079 IRGPQGHQGPA 1089



 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 207/1054 (19%), Positives = 274/1054 (25%), Gaps = 65/1054 (6%)

Query: 247  GVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 306
            G       QG A E    G T    A G A      G        G   E  V G     
Sbjct: 106  GAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGAR 165

Query: 307  AVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVA 366
               G        G+   +    +     A G+  E    G       +G   +  A G+ 
Sbjct: 166  GFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPG------ENGTPGQTGARGLP 219

Query: 367  KEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPD--AAHGIANEVAAHGIANED 424
             E    G        G    D   G V       +   P    A G   E+ A G A   
Sbjct: 220  GE---RGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPA 276

Query: 425  AAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVA 484
               G   EV   G+S      G      A G+     A+G A    V G        G+ 
Sbjct: 277  GPAGPRGEVGLPGLS---GPVGPPGNPGANGLT---GAKGAAGLPGVAGAPGLPGPRGIP 330

Query: 485  KEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAH 544
              V A G               ARG+  E    G   E    G        G        
Sbjct: 331  GPVGAAGATG------------ARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEE 378

Query: 545  GVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIED 604
            G    +     A P    G+     ++G+   D   G+     + G +    V G   + 
Sbjct: 379  GKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDA 438

Query: 605  AVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAI 664
               G        G+       G A +    G+   D   G +      G    E      
Sbjct: 439  GRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARG----EPGNIGF 494

Query: 665  AKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAA 724
              P    G   +    G A    A+G    D   G        G+      QG       
Sbjct: 495  PGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGF 554

Query: 725  QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHE 784
            QG+       G   +    G+  E    G A     +G   E    G    +  +G    
Sbjct: 555  QGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRG---- 610

Query: 785  DAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGV 844
                G    D   G    V A G A      G+  E  A G+       G   E    G+
Sbjct: 611  --PSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIP------GGKGEKGEPGL 662

Query: 845  AKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGI 904
              E+   G        G V      G   +   A A      A    + G   EV   G 
Sbjct: 663  RGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAG- 721

Query: 905  ATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQ 964
                 A         G   E  A+    ++     T    A G A  +   G A      
Sbjct: 722  -PNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDG 780

Query: 965  GVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEV 1024
            G        G A      G +      G++      G A K+ ++G   +    G   EV
Sbjct: 781  GPPGMTGFPGAAGRTGPPGPS------GISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEV 834

Query: 1025 AAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIA 1084
             A G       +G + E    G        G+     + G+      +G+     A G  
Sbjct: 835  GAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVG-- 892

Query: 1085 HEDAVQGIANEDAVHGVAKEVAAHGV------ANEDPVQGVANEDAVQGVANEVEVQGVA 1138
             E    GIA      G    V + GV      A  D   G        G       +G  
Sbjct: 893  -EPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYP 951

Query: 1139 HEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVH 1198
                  G A     HG       HG   E    G      A G       QGI  +    
Sbjct: 952  GNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEP 1011

Query: 1199 GVAKEVAAHGVANEDAAH---AIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVA 1255
            G        G+   +       IA     +G    V   G        G A +D   G  
Sbjct: 1012 GEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHP 1071

Query: 1256 NEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQG 1289
              V   GI      QG A      G      V G
Sbjct: 1072 GTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSG 1105



 Score = 87.8 bits (216), Expect = 1e-16
 Identities = 204/1084 (18%), Positives = 278/1084 (25%), Gaps = 68/1084 (6%)

Query: 667  PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG 726
            P      A +    G+       G+       G A      G        G   +    G
Sbjct: 71   PGLGGNFAAQYDGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAG 130

Query: 727  IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDA 786
                    G A ED   G        GV      +G      + G       +GI   + 
Sbjct: 131  ARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGF------KGIRGHNG 184

Query: 787  VQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAK 846
            + G+  +  A G+  E  A G        G       +G        G    D + G   
Sbjct: 185  LDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVG 244

Query: 847  EVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIAT 906
                 G        G    +   G V N   A   A P    G+   G++  V   G   
Sbjct: 245  PAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGP-AGPRGEVGLP--GLSGPVGPPG--- 298

Query: 907  EDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGV 966
                       A+G+T  + A  +                GVA      G        G 
Sbjct: 299  --------NPGANGLTGAKGAAGLP---------------GVAGAPGLPGPRGIPGPVGA 335

Query: 967  ANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAA 1026
            A    A+G+  E    G   E   +G       QG       +G    +   G A     
Sbjct: 336  AGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGP 395

Query: 1027 HGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQ----------GIAN 1076
             G+     ++G+   D   G+     + G S    V+G  N DA +          G+  
Sbjct: 396  PGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRG-PNGDAGRPGEPGLMGPRGLPG 454

Query: 1077 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQG 1136
                 G A ++   G+   D   G      A G        G        G   +    G
Sbjct: 455  SPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAG 514

Query: 1137 VAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDA 1196
            +A     +G    D  +G        G+      QG       QG+       G   +  
Sbjct: 515  LA---GARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPG 571

Query: 1197 VHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVAN 1256
              G+  E    G A             A G    + ++G +     DG   E    G   
Sbjct: 572  ERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVG 631

Query: 1257 EVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQG 1316
                 G S     +G A     +G   E  ++G        G        G        G
Sbjct: 632  TAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATG 691

Query: 1317 VANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDA 1376
               E    G A     +G   E    G A  +   G A          E  A+G   E+ 
Sbjct: 692  DRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENG 751

Query: 1377 VQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIAN 1436
            V G      A G A  +   G A      G        G A      G +      G   
Sbjct: 752  VVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPG 811

Query: 1437 EVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHA 1496
                 G+      QG        G        G        G A      G      A  
Sbjct: 812  PAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPG 871

Query: 1497 IAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDA 1556
            I     +RG        G   E    GIA    A G    V + G+       G A  D 
Sbjct: 872  ILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVN---GAPGEAGRDG 928

Query: 1557 VQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIA 1616
              G        G    D   G   E      +    AA A       HG          A
Sbjct: 929  NPG------NDGPPGRDGQPGHKGERGYPGNIGPVGAAGA----PGPHGPVGP------A 972

Query: 1617 NKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQ 1676
             K   +G        G A  V   G S    ++G   E   +G       +G      + 
Sbjct: 973  GKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLP 1032

Query: 1677 GIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANED 1736
            GIA      G    V   G        G A +D   G    V   G+      QG A   
Sbjct: 1033 GIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPP 1092

Query: 1737 AAHG 1740
               G
Sbjct: 1093 GPPG 1096



 Score = 84.7 bits (208), Expect = 1e-15
 Identities = 212/1067 (19%), Positives = 289/1067 (27%), Gaps = 84/1067 (7%)

Query: 1234 QGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANE 1293
            Q +  E V  G A +    G        G   ED   G        G        G+   
Sbjct: 23   QSLQEETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPG------PPGLGGN 76

Query: 1294 DAAQ----GIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDA 1349
             AAQ    G+       G+       G A     QG       QG A E    G      
Sbjct: 77   FAAQYDGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGF------QGPAGEPGEPGQTGPAG 130

Query: 1350 AQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVAN 1409
            A+G A        A ED   G       +G+     A+G        G       +G+  
Sbjct: 131  ARGPAGPPGK---AGEDGHPGKPGRPGERGVVGPQGARGFP------GTPGLPGFKGIRG 181

Query: 1410 EVEVQGVAHEDAVQGIANEDAA---HGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDA 1466
               + G+  +    G+  E  A   +G   +  A G+  E    G      A+G      
Sbjct: 182  HNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVG 241

Query: 1467 VQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIAT------EDV 1520
              G A      G      A G   E  A   A P    G   EV   G++          
Sbjct: 242  PVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPG 301

Query: 1521 ADGIANEDAAHGVANEVAAQGIANEVAVHG---VAIEDAVQGVVKEVTAHGVANEDAVQG 1577
            A+G+     A G+     A G+     + G    A     +G+V E    G   E   +G
Sbjct: 302  ANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKG 361

Query: 1578 VVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEV 1637
                             +    P+   G A       +     ++G+   D   G+    
Sbjct: 362  EPGSAGPQGP-PGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPP 420

Query: 1638 AAHGISKEDAVQGIANEDAAQ----------GIANEDAAQGIAHEDAVQGIANEDAVHGV 1687
             + G S    V+G  N DA +          G+       G A ++   G+   D   G 
Sbjct: 421  GSRGASGPAGVRG-PNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGP 479

Query: 1688 AKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAA 1747
                 A G        G        G   +    G+A     +G    D  +G       
Sbjct: 480  IGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLA---GARGAPGPDGNNGAQGPPGP 536

Query: 1748 HGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANE 1807
             G+      QG       QG+           +    G+  E      A P   RG   E
Sbjct: 537  QGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGE 596

Query: 1808 VAAQGIATEDVAD----GIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDP 1863
              A G  T  +      G P  D   G    V A G +      G+  E  A GI     
Sbjct: 597  SGAAG-PTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGG-- 653

Query: 1864 IQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISK 1923
             +G   E  ++G        G      A G      A G   E  A   A     +G   
Sbjct: 654  -KGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPG 712

Query: 1924 EDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQG 1983
            E    G A  +   G A      G   E  A+G   E    G      A G A  +   G
Sbjct: 713  ERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPG 772

Query: 1984 IAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDA 2043
             A      G   +    G+     A     P    GI+      G A ++   G   +  
Sbjct: 773  PA------GSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQG 826

Query: 2044 AHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDA----VQGITNEEAAQAIAKQ 2099
              G   E  A           +   G A E    G A  A      G      A  I   
Sbjct: 827  PVGRTGEVGA-----------VGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGL 875

Query: 2100 DAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGV 2159
              + G        G   E    G+A    A G    V + GV       G        G 
Sbjct: 876  PGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGP 935

Query: 2160 ANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAA 2219
               D   G   E   +G        G A      G       HG   E    G      A
Sbjct: 936  PGRDGQPGHKGE---RGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGA 992

Query: 2220 QGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHG 2266
             G       QG+  +    G         +   +  QG+      HG
Sbjct: 993  VGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHG 1039



 Score = 84.0 bits (206), Expect = 2e-15
 Identities = 173/934 (18%), Positives = 245/934 (26%), Gaps = 36/934 (3%)

Query: 1379 GIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEV 1438
            G A     QG        G   +    G        G A ED   G        G+    
Sbjct: 103  GAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQ 162

Query: 1439 AAHGIANEDAA---QGIANEDAAQGIAHEDAVQGIANEDAV---HGVAKEVAAHGVANED 1492
             A G          +GI   +   G+  +    G+  E      +G   +  A G+  E 
Sbjct: 163  GARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGER 222

Query: 1493 AAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVA 1552
                   P  ARG    V   G A    + G      A G   E+ A G A      G  
Sbjct: 223  GRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPR 282

Query: 1553 IEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAA 1612
             E  + G+   V   G    + + G      L  V            P    G A    A
Sbjct: 283  GEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPV-GAAGATGA 341

Query: 1613 HSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHE 1672
              +  +    G   +   +G        G       +G    +   G A      G+   
Sbjct: 342  RGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGS 401

Query: 1673 DAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGI 1732
               +G+   D   GV     + G +    V+G   +    G    +  +G+       G 
Sbjct: 402  PGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGP 461

Query: 1733 ANEDAAHGITN------EVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGV 1786
            A ++   G+         +   G   E    G        G   ++     A    A G 
Sbjct: 462  AGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGA 521

Query: 1787 ANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAV 1846
               D  +    P   +G+      QG        G+P      G   +    G+  E  +
Sbjct: 522  PGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGL 581

Query: 1847 QGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANE 1906
             G A     +G   E    G    +  +G +      G   E    G        G +  
Sbjct: 582  PGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGL 641

Query: 1907 DAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGI 1966
               +  A     +G   E  ++G        G        G      A G   E  A G 
Sbjct: 642  PGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGP 701

Query: 1967 ANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAA 2026
            A     +G   E    G A  +   G A      G   E  A      +   G    V A
Sbjct: 702  AGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGA 761

Query: 2027 QGIATEDVADGIANE------------DAAHGVANEDAAQAIAKPDAAHGIAN-EGIATE 2073
             G A  +   G A                A G         I+ P    G A  EG+   
Sbjct: 762  AGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGP 821

Query: 2074 DVADG-------IAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANE 2126
                G       +      G   E+     A      G        G    +   G   E
Sbjct: 822  RGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGE 881

Query: 2127 DAAHGVANEVAAHG---VANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAI 2183
                GVA  V   G   +A    A+G    V + GV       G        G   +D  
Sbjct: 882  RGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQ 941

Query: 2184 QGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANE 2243
             G   E    G    V A G        G A +   +G        G A  V   G +  
Sbjct: 942  PGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGP 1001

Query: 2244 DAARHMAKEDAAQGIANEDAAHGIANEDAVHGIA 2277
               R    E   +G        G      + GIA
Sbjct: 1002 QGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIA 1035



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 96/518 (18%), Positives = 139/518 (26%), Gaps = 26/518 (5%)

Query: 1785 GVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKED 1844
            G A E        P  ARG A      G A ED   G P      GV     A G     
Sbjct: 115  GPAGEPGEPGQTGPAGARGPAGP---PGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTP 171

Query: 1845 AVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIA 1904
             + G        G+   D ++G      V+G        G   +  A G+  E    G  
Sbjct: 172  GLPGFKGIRGHNGL---DGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAP 228

Query: 1905 NEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAH 1964
                A+         G +      G      A G   E    G A      G   EV   
Sbjct: 229  GPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLP 288

Query: 1965 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEV 2024
            G++      G    +   G      + G+A    + G          A    ARG+  E 
Sbjct: 289  GLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEP 348

Query: 2025 AAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANE----GIATEDVADGI- 2079
               G   E    G        G       +    P+   G A      G+     + G+ 
Sbjct: 349  GPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLP 408

Query: 2080 AEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAH 2139
              D   G+     ++  +      G   +    G    +  +G+       G A +    
Sbjct: 409  GADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPV 468

Query: 2140 GVANEDAAQGVANEVAAQGVAN---------------EDAVQGVANEVEVQGIAHKDAIQ 2184
            G+   D   G      A+G                  ++  +G A     +G    D   
Sbjct: 469  GLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNN 528

Query: 2185 GIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANED 2244
            G       QGV       G       QG+       G   +   +G+  E  + G A   
Sbjct: 529  GAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPR 588

Query: 2245 AARHMAKEDAAQGIANEDAAHGIANEDAVHGIANEDAV 2282
              R    E  A G      + G +      G   E  V
Sbjct: 589  GERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGV 626



 Score = 45.1 bits (105), Expect = 8e-04
 Identities = 69/356 (19%), Positives = 96/356 (26%), Gaps = 6/356 (1%)

Query: 1931 ANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAV 1990
            A Q   +G+       G+       G A      G        G   +    G       
Sbjct: 78   AAQYDGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGP 137

Query: 1991 QGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAA---QGIATEDVADGIANEDAAHGV 2047
             G A ED   G         +  P  ARG          +GI   +  DG+  +  A GV
Sbjct: 138  PGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGV 197

Query: 2048 ANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDA-VQGITNEEAAQAIAKQDAAHGIT 2106
              E  A          G    G+  E    G    A  +G          A    + G  
Sbjct: 198  KGEPGAPGENGTPGQTGA--RGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPP 255

Query: 2107 KEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQ 2166
                A G   E+ A G A      G   EV   G++      G        G      + 
Sbjct: 256  GFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLP 315

Query: 2167 GVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANED 2226
            GVA    + G        G A    A+G+  E    G   E   +G       QG     
Sbjct: 316  GVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPS 375

Query: 2227 AAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVHGIANEDAV 2282
              +G        G A       +     ++G+   D   G+       G +    V
Sbjct: 376  GEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGV 431


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score =  100 bits (248), Expect = 2e-20
 Identities = 202/1083 (18%), Positives = 298/1083 (27%), Gaps = 68/1083 (6%)

Query: 959  NEDAAQGVANEVAAQGVAN--EDAVHGVANEDAVQGVANEVE----VQGIAHKDAIQGIA 1012
            ++D   G   E+    +    E+A HG       +G    +E    V+G    +   G+ 
Sbjct: 265  SQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLI 324

Query: 1013 NEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQ-GIANEDAA 1071
                  G    V   G        G+   D A G        G S     + G    D  
Sbjct: 325  GPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPG------PPGTSLMLPFRFGSGGGDKG 378

Query: 1072 QGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANE 1131
              +A ++A      + A   +       G        G      ++G + +   QG    
Sbjct: 379  PVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGP 438

Query: 1132 VEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGI 1191
              + G   +   +G A  D A G+  +    G    D   G+  E   +G      + G 
Sbjct: 439  QGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGP 498

Query: 1192 ANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAA 1251
              ED   G   E+   G+  E     +  P    GI      +G+       G       
Sbjct: 499  PGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGE 558

Query: 1252 HGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQG-IAKEDPVQGVAN 1310
             G   +    G       QG       +G   +  + G+   D   G   KE P     N
Sbjct: 559  PGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGN 618

Query: 1311 EDPI--QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAA 1368
            + P   QG       +GV   D ++G+               +G   ED       +   
Sbjct: 619  QGPSGPQGPLGYPGPRGVKGVDGIRGLKGH------------KGEKGEDGFPGFKGDIGV 666

Query: 1369 QGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANE 1428
            +G   E  V G   ED  +G        G      + G   ++ V G      + G    
Sbjct: 667  KGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG------LPGYPGR 720

Query: 1429 DAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGV 1488
                G        G + E  A+G++ +   +G   E    G   +    G   +  A G 
Sbjct: 721  QGPKGSLGFPGFPGASGEKGARGLSGKSGPRG---ERGPTGPRGQRGPRGATGKSGAKGT 777

Query: 1489 ANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAV 1548
            +  D  H    P   RG+       G        G   +D   G   +    G   +   
Sbjct: 778  SGGDGPHG---PPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGP 834

Query: 1549 HGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIAN 1608
             G       QG   E    G        G   E  L    A ++  +    P  A G   
Sbjct: 835  PGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPG-TAGKEGTKGDPGPPGAPG--- 890

Query: 1609 EVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQ---GIANEDAAQGIANEDA 1665
                     KD   G+      +G+       G+   +      G A     +G A    
Sbjct: 891  ---------KDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGG 941

Query: 1666 AQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAH 1725
              G       QG        GV  E    G    D VQG        G+       GVA 
Sbjct: 942  PIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPV------GLPGPAGPPGVAG 995

Query: 1726 EDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHG 1785
            ED  +G   +    G       HG        G   +    G   E           A G
Sbjct: 996  EDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKG 1055

Query: 1786 VANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDA 1845
                   +    P   +G+      +G   +    G P      G A    A G      
Sbjct: 1056 DEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPG 1115

Query: 1846 VQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIAN 1905
              G       +G   E    G+  E  V+G   E   +G   E    G       +G   
Sbjct: 1116 GVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGE---RGEKGESGQPGEPGPPGPKGPTG 1172

Query: 1906 EDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHG 1965
            +D  +         G        G   QD A+G   ED   G   +  + G   E    G
Sbjct: 1173 DDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG---QPGSPGPTGENGPPG 1229

Query: 1966 IANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVA 2025
               +    G    +  QG        G        G            PD  RG+   V 
Sbjct: 1230 PLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVG 1289

Query: 2026 AQG 2028
             QG
Sbjct: 1290 QQG 1292



 Score = 94.7 bits (234), Expect = 9e-19
 Identities = 191/1067 (17%), Positives = 289/1067 (27%), Gaps = 62/1067 (5%)

Query: 923  KEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVH 982
            +E  AQAI +Q A  ++       G        G       +G + ++  QG      + 
Sbjct: 384  QEAQAQAILQQ-ARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLT 442

Query: 983  GVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANED 1042
            G   +   +G A     +G+     ++G    D   G+  E    G        G   ED
Sbjct: 443  GPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED 502

Query: 1043 AAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVA 1102
              +G   E+   G+  E   +G+       GI      +G+      +G        G  
Sbjct: 503  GERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPP 562

Query: 1103 KEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAA- 1161
             +    G       QG       +G   +  + G+   D   G   ++   G        
Sbjct: 563  GQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPS 622

Query: 1162 -----------HGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVA 1210
                        G+   D  +G+      +G   ED   G   +  V G   EV   G  
Sbjct: 623  GPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG---EDGFPGFKGDIGVKGDRGEVGVPGSR 679

Query: 1211 NEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQ 1270
             ED       P+  +G        G        G+  E    GV              + 
Sbjct: 680  GEDG------PEGPKGRTGPTGDPG------PPGLMGEKGKLGV------------PGLP 715

Query: 1271 GIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHED 1330
            G       +G        G + E  A+G++ +    G   E    G   +   +G   + 
Sbjct: 716  GYPGRQGPKGSLGFPGFPGASGEKGARGLSGK---SGPRGERGPTGPRGQRGPRGATGKS 772

Query: 1331 AVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIA 1390
              +G +  D  HG   E   +G+                G   +D + G   +    G  
Sbjct: 773  GAKGTSGGDGPHGPPGE---RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQ 829

Query: 1391 KEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQ 1450
             +    G       QG A E    G        G   E    G A +    G      A 
Sbjct: 830  GKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAP 889

Query: 1451 GIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEV 1510
            G       +G   E  + G A    + G        G A        A      G     
Sbjct: 890  GKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP 949

Query: 1511 ATQGIATEDVADGIANEDAAHGVANEVAAQ---GIANEVAVHGVAIEDAVQGVVKEVTAH 1567
              QG        G+  E    G       Q   G+       GVA ED  +G V +    
Sbjct: 950  GPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQK 1009

Query: 1568 GVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQ 1627
            G        G          V    AA A  +P  A G      A          G    
Sbjct: 1010 GTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEP-GARGPQGHFGAKGDEGTRGFNGPPGP 1068

Query: 1628 DAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1687
               QG+       G + +    G       +G A  + A G        G        G 
Sbjct: 1069 IGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1128

Query: 1688 AKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAA 1747
              E  + G+  E  V+G   E   +G + +    G       +G   +D   G    V  
Sbjct: 1129 PGESGSPGIQGEPGVKGPRGERGEKGESGQ---PGEPGPPGPKGPTGDDGPKGNPGPVGF 1185

Query: 1748 HGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANE 1807
             G        G   +D  +G   ED       E    G       +    P   RG A  
Sbjct: 1186 PGDPGPPGEGGPRGQDGAKGDRGEDG------EPGQPGSPGPTGENGPPGPLGKRGPAGS 1239

Query: 1808 VAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGV 1867
              ++G      A G P    A G    V   G + +    G+     + G   +    G 
Sbjct: 1240 PGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVG---QQGRPGA 1296

Query: 1868 ANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAV 1927
              +    G      + G+  +  A G        G+      Q    +    G       
Sbjct: 1297 TGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQ 1356

Query: 1928 QGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQG 1974
            +G      A G        G+      +G        G   E   QG
Sbjct: 1357 KGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQG 1403



 Score = 94.7 bits (234), Expect = 9e-19
 Identities = 173/939 (18%), Positives = 255/939 (27%), Gaps = 28/939 (2%)

Query: 62   ADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQG 121
            AD A G+  +  V+G        G+  E    G        G   ED  +G   E+  +G
Sbjct: 456  ADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRG 515

Query: 122  VANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDA 181
            +  E   +G+       G+     V+G+       G        G   +           
Sbjct: 516  LPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPG 575

Query: 182  AQDIANEDAAQGISKEDAVQGIANEDAAQG-IAKEDPVQGVANEDP--VQGVANEDAVQG 238
             Q        +G   +  + G+   D   G   KE P     N+ P   QG       +G
Sbjct: 576  PQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRG 635

Query: 239  VANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDA 298
            V     V G+      +G   ED   G   ++   G   E    G   ED  +G      
Sbjct: 636  VKG---VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTG 692

Query: 299  VQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIAN 358
              G      + G   ++   G+                G       +G        G   
Sbjct: 693  PTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG 752

Query: 359  EDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAH 418
            E    G   +    G   +   +G    D  HG        + +  P   +G        
Sbjct: 753  ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHG----PPGERGLPGPQGPNGFPGPKGPP 808

Query: 419  GIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANED 478
            G   +D   G   +    G   +    G       QG A E    G        G   E 
Sbjct: 809  GPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQ 868

Query: 479  AVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVA 538
             + G A +    G      A     P   RG   E    G A      G        G A
Sbjct: 869  GLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPA 928

Query: 539  NEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVH 598
                  G A               G       +G+  E    G    D   GV   V + 
Sbjct: 929  GSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRD---GVQGPVGLP 985

Query: 599  GVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANE 658
            G A      GVA ED   G   +   +G       HG        G V +    G    E
Sbjct: 986  GPA---GPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAG-ADGE 1041

Query: 659  DAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGI 718
              A+       A G       +G       QG+      +G   +V   G       +G 
Sbjct: 1042 PGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGP 1101

Query: 719  ANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEV 778
            A  + A G        G        G   E  + G+  E  V+G   E   +G   E   
Sbjct: 1102 AGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGE---RGEKGESGQ 1158

Query: 779  QGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANE 838
             G       +G   +D   G    V   G        G   +D A+G   ED   G   +
Sbjct: 1159 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGED---GEPGQ 1215

Query: 839  DAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANE 898
              + G   E    G   +    G    E   G    +    AI  P     +   G A +
Sbjct: 1216 PGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1275

Query: 899  VAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVA 958
                G+    +   + +    G T +              +  +  A+G        G+ 
Sbjct: 1276 PGPDGL--RGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLI 1333

Query: 959  NEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEV 997
                 QG   E   +G+       G   E  + G +  +
Sbjct: 1334 GPPGEQG---EKGDRGLPGPQGSPGQKGEMGIPGASGPI 1369



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 195/1042 (18%), Positives = 294/1042 (28%), Gaps = 72/1042 (6%)

Query: 392  VVANEDAAQAIAK--------PDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDA 443
            V A E  AQAI +        P    G        G       +G + ++   G      
Sbjct: 381  VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQG 440

Query: 444  VQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAK 503
            + G   +   +G A  D A+G+  +  V+G    D + G+  E    G            
Sbjct: 441  LTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 500

Query: 504  PDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHG 563
             D  RG   E+  +G+  E    G+       G+       G+           P    G
Sbjct: 501  EDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPG 560

Query: 564  IANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANE-- 621
               +  T G        G        G   +  + G+   D   G   ++   G      
Sbjct: 561  PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQG 620

Query: 622  -DAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAH 680
                QG        GV   D ++G+       G    ED            G   EV   
Sbjct: 621  PSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG----EDGFPGFKGDIGVKGDRGEVGVP 676

Query: 681  GIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANED 740
            G   ED  +G        G        G   +  V G+      QG       +G     
Sbjct: 677  GSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQG------PKGSLGFP 730

Query: 741  AVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIA 800
               G + E  A G++ +    G   E    G   +   +G   +   +G +  D  HG  
Sbjct: 731  GFPGASGEKGARGLSGK---SGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPP 787

Query: 801  NEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQ 860
             E    G+       G        G   +D + G        G   EV   G T      
Sbjct: 788  GE---RGLPGPQGPNGFPGPKGPPGPPGKDGLPG------HPGQRGEVGFQGKTGPPGPP 838

Query: 861  GVVNEEALHGVVA--NEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAA 918
            GVV  +   G      E        P    G+   G A +   +G      A G  KD  
Sbjct: 839  GVVGPQGAAGETGPMGERGHPGPPGPPGEQGL--PGTAGKEGTKGDPGPPGAPG--KDGP 894

Query: 919  HGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANE 978
             G+      + +        +   +   G      + G   E  A G    +   G    
Sbjct: 895  AGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPG---ERGAAGSGGPIGPPGRPGP 951

Query: 979  DAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGI 1038
                G A E  V G    +   G   +D +QG        G+       G+A ED  +G 
Sbjct: 952  QGPPGAAGEKGVPGEKGPI---GPTGRDGVQGPV------GLPGPAGPPGVAGEDGDKGE 1002

Query: 1039 ANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAV 1098
              +   +G       HG        G   +  A G   E  A+G       +G   ++  
Sbjct: 1003 VGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKG---DEGT 1059

Query: 1099 HGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANE 1158
             G       +G      +QG+      +G   +V   G       +G A  + A G    
Sbjct: 1060 RGF------NGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGP 1113

Query: 1159 VAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAI 1218
                G       +G   E  + GI  E  V+G   E    G   E    G          
Sbjct: 1114 PGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGE---RGEKGESGQPGEPGPPGPKGP 1170

Query: 1219 AKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAA 1278
               D  +G    V   G        G   +D A G   E    G   +    G   E+  
Sbjct: 1171 TGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG---QPGSPGPTGENGP 1227

Query: 1279 QGIAKEDAVQGIANEDAAQG--IAKEDP-VQGVANEDPIQGVANEVEVQGVAHEDAVQGI 1335
             G   +    G    +  QG   AK DP   G   +    G A      G      + G 
Sbjct: 1228 PGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGS 1287

Query: 1336 ANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPV 1395
              +    G   +    G         +  +  A+G      + G+      QG   E   
Sbjct: 1288 VGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQG---EKGD 1344

Query: 1396 QGVANEDAVQGVANEVEVQGVA 1417
            +G+       G   E+ + G +
Sbjct: 1345 RGLPGPQGSPGQKGEMGIPGAS 1366



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 190/1017 (18%), Positives = 273/1017 (26%), Gaps = 73/1017 (7%)

Query: 916  DAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGV 975
            D A G+  +   +     D    +  E   +G        G   ED  +G   E+  +G+
Sbjct: 457  DGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGL 516

Query: 976  ANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAA 1035
              E    G+       G+     V+G+      +G        G   +    G       
Sbjct: 517  PGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGP 576

Query: 1036 QGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANE 1095
            QG       +G   +    G+   D   G   ++   G        G        G    
Sbjct: 577  QGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGV 636

Query: 1096 DAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGI 1155
              V G+       G   ED   G   +  V+G   EV V G   ED  +G        G 
Sbjct: 637  KGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEG---PKGRTGP 693

Query: 1156 ANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAA 1215
              +    G+  E    G+       G       +G        G + E  A G++ +   
Sbjct: 694  TGDPGPPGLMGEKGKLGV---PGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGP 750

Query: 1216 HAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANE 1275
                 P   RG   +   +G   +  A G +  D  HG   E    G+       G    
Sbjct: 751  RGERGPTGPRG---QRGPRGATGKSGAKGTSGGDGPHGPPGE---RGLPGPQGPNGFPGP 804

Query: 1276 DAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGI 1335
                G   +D + G   +    G   +    G       QG A E    G        G 
Sbjct: 805  KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGP 864

Query: 1336 ANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPV 1395
              E    G A ++  +G      A         +G   E  + G A     +G       
Sbjct: 865  PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP 924

Query: 1396 QGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANE 1455
             G A     +G A      G       QG        G+  E    G    D  QG    
Sbjct: 925  PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQG---- 980

Query: 1456 DAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGI 1515
                G+       G+A ED   G   +    G       H    P    G   +    G 
Sbjct: 981  --PVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAG- 1037

Query: 1516 ATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAV 1575
                 ADG   E  A G      A+G       +G      +QG+       G + E   
Sbjct: 1038 -----ADG---EPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGL------PGPSGEKGE 1083

Query: 1576 QGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIAN 1635
             G V                    P    G A    A          G       +G   
Sbjct: 1084 TGDV-------------GPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG 1130

Query: 1636 EVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHG 1695
            E  + GI  E  V+G   E   +G   E    G       +G   +D   G    V   G
Sbjct: 1131 ESGSPGIQGEPGVKGPRGERGEKG---ESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPG 1187

Query: 1696 VANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDA 1755
                    G   +D  +G       +G   E    G       +G    +   G A    
Sbjct: 1188 DPGPPGEGGPRGQDGAKG------DRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPG 1241

Query: 1756 AQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIAT 1815
            ++G       +G             V   G A +        PD  RG+   V  QG   
Sbjct: 1242 SEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPG------PDGLRGLPGSVGQQGRPG 1295

Query: 1816 EDVADGIP---NEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVE 1872
                 G P         G+  +  A G      + G+      QG   +  + G      
Sbjct: 1296 ATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPG------ 1349

Query: 1873 VQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQG 1929
             QG   +    GI       G        G A    A+        +G   E  VQG
Sbjct: 1350 PQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKG---EKGVQG 1403



 Score = 88.6 bits (218), Expect = 7e-17
 Identities = 172/896 (19%), Positives = 247/896 (27%), Gaps = 79/896 (8%)

Query: 654  VVANEDAAQAIAK--------PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVA 705
            V A E  AQAI +        P    G        G       +G + +   QG      
Sbjct: 381  VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQG 440

Query: 706  AHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVAN 765
              G   +   +G A  D A+G+  +  V+G    D + G+  E    G      + G   
Sbjct: 441  LTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 500

Query: 766  EDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQG 825
            ED  +G   E+  +G+  E   +G+       GI       GV   D  QG       QG
Sbjct: 501  EDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIP---GPPGVRGMDGPQGPKGSLGPQG 557

Query: 826  VANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPD 885
                    G        G    +  HG   E   QG   +  L G+  ++       K  
Sbjct: 558  EPGPPGQQGTPGTQGLPGPQGAIGPHG---EKGPQG---KPGLPGMPGSDGPPGHPGKEG 611

Query: 886  AAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAA 945
                  N+G +      G        G+                                
Sbjct: 612  PPGTKGNQGPSGPQGPLGYPGPRGVKGV-------------------------------- 639

Query: 946  QGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHK 1005
             G+       G   ED   G   ++  +G   E  V G   ED  +G        G    
Sbjct: 640  DGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGP 699

Query: 1006 DAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGI 1065
              + G   +    G+       G       +G        G + E  A G+S +   +G 
Sbjct: 700  PGLMGEKGKLGVPGLP------GYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG- 752

Query: 1066 ANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAV 1125
              E    G   +   +G   +   +G +  D  HG   E            +G+      
Sbjct: 753  --ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGE------------RGLPGPQGP 798

Query: 1126 QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHE 1185
             G        G   +D + G   +    G   +    G       QG A E    G    
Sbjct: 799  NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 858

Query: 1186 DAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGI 1245
                G   E  + G A +    G      A     P   RG   E    G A      G 
Sbjct: 859  PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 918

Query: 1246 ANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPV 1305
                   G A      G +      G       QG       +G+  E    G    D V
Sbjct: 919  EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGV 978

Query: 1306 QG-VANEDPI--QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDI 1362
            QG V    P    GVA E   +G   +   +G       HG        G   +  A   
Sbjct: 979  QGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGA 1038

Query: 1363 ANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAV 1422
              E  A+G       +G        G      +QG+      +G   +V   G       
Sbjct: 1039 DGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGP 1098

Query: 1423 QGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE 1482
            +G A  + A G        G       +G   E  + GI  E  V+G   E    G + +
Sbjct: 1099 RGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQ 1158

Query: 1483 ------VAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHG 1532
                      G   +D       P    G        G   +D A G   ED   G
Sbjct: 1159 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG 1214



 Score = 87.4 bits (215), Expect = 1e-16
 Identities = 177/965 (18%), Positives = 263/965 (27%), Gaps = 65/965 (6%)

Query: 1306 QGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANE 1365
            +G A  D  +G+  +  V+G    D + G+  E    G        G   ED  +    E
Sbjct: 451  RGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGE 510

Query: 1366 DAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGI 1425
               +G+  E   +G+       GI     V+G+   D  QG    +  QG       QG 
Sbjct: 511  IGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGM---DGPQGPKGSLGPQGEPGPPGQQGT 567

Query: 1426 ANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAA 1485
                   G    +  HG        G+     + G       +G        G +     
Sbjct: 568  PGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPS---GP 624

Query: 1486 HGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANE 1545
             G         +   D  RG+      +G            ED   G   ++  +G   E
Sbjct: 625  QGPLGYPGPRGVKGVDGIRGLKGHKGEKG------------EDGFPGFKGDIGVKGDRGE 672

Query: 1546 VAVHGVAIEDAVQGVVKEVTAHGVANEDAV---QGVVNEDALHSVVANEDAAQAIAKPDA 1602
            V V G   ED  +G        G      +   +G +    L      +    ++  P  
Sbjct: 673  VGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGF 732

Query: 1603 AHGIANEVAAHSIANKDAAQGIAN------QDAAQGIANEVAAHGISKEDAVQGIANEDA 1656
              G + E  A  ++ K   +G         Q   +G   +  A G S  D   G   E  
Sbjct: 733  P-GASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGE-- 789

Query: 1657 AQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVAN 1716
             +G+       G        G   +D + G        G   E   QG        GV  
Sbjct: 790  -RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHP------GQRGEVGFQGKTGPPGPPGV-- 840

Query: 1717 EVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHS 1776
             V  QG A E    G        G   E    G A ++  +G        G      +  
Sbjct: 841  -VGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRG 899

Query: 1777 VAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVA 1836
               E    G A          P    G A     +G A      G P      G      
Sbjct: 900  FPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAG 959

Query: 1837 AHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIAN 1896
              G+  E    G    D  QG     P+ G+       GVA ED  +G   +    G   
Sbjct: 960  EKGVPGEKGPIGPTGRDGVQG-----PV-GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKG 1013

Query: 1897 EDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQG 1956
                 G            +  A G   E   +G      A+G   ++  +G        G
Sbjct: 1014 NKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKG---DEGTRGF------NG 1064

Query: 1957 IANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDA 2016
                +   G+      +G   +    G       +G A  +   G            P  
Sbjct: 1065 PPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPG 1124

Query: 2017 ARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVA 2076
             +G   E  + GI  E    G   E    G + +        P    G  ++G       
Sbjct: 1125 EKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTG--DDGPKGNPGP 1182

Query: 2077 DGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEV 2136
             G   D   G   E   +    QD A G   ED   G        G        G     
Sbjct: 1183 VGFPGDP--GPPGEGGPRG---QDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPA 1237

Query: 2137 AAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVA 2196
             + G       +G   +  A G   +    G A      G      + G   +    G  
Sbjct: 1238 GSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGAT 1297

Query: 2197 NEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQ 2256
             +    G        G+  +  A+G   E    G+   +   G   E   R +     + 
Sbjct: 1298 GQAGPPGPVGPPGLPGLRGDAGAKG---EKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSP 1354

Query: 2257 GIANE 2261
            G   E
Sbjct: 1355 GQKGE 1359



 Score = 86.3 bits (212), Expect = 3e-16
 Identities = 217/1217 (17%), Positives = 330/1217 (27%), Gaps = 87/1217 (7%)

Query: 16   SSEESLVHKDRGDGERPVNVRVVQVAPLRHESTPYEDT--VHDIANEDADAAHGITNEDA 73
            S E+  +  + G  ERP N +     P R + +P +    +H   N++  +      +D 
Sbjct: 220  SCEQKELECEGGQRERPQNQQ-----PHRAQRSPQQQPSRLHRPQNQEPQS------QDP 268

Query: 74   VQGVANEVAAQGVAN--EDAAHGVANEVAAHG----------VANEDAAQGVANEVAAQG 121
              G   E+    +    E+AAHG        G          V      +G A  +   G
Sbjct: 269  TPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPG 328

Query: 122  VANEDAVQGVANEDAVQGVANEDAVQGIANEDAAH-------GIANEDAAQGIANEDAAQ 174
            +       G   E    G A      G               G    D    +A ++A  
Sbjct: 329  IQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQA 388

Query: 175  DIAKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANED 234
                + A   +       G +      G       +G + +   QG      + G   + 
Sbjct: 389  QAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKA 448

Query: 235  AVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIA 294
              +G A     +G+  +  V+G    D   G+  E    G        G   ED  +G  
Sbjct: 449  GRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDD 508

Query: 295  HEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVAD 354
             E   +G+  E    G+       G+        +   D   G    +  QG        
Sbjct: 509  GEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGM---DGPQGPKGSLGPQGEPGPPGQQ 565

Query: 355  GIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANE 414
            G        G    +  HG   E   QG   +  L G+  ++        P    G    
Sbjct: 566  GTPGTQGLPGPQGAIGPHG---EKGPQG---KPGLPGMPGSDG-------PPGHPGKEGP 612

Query: 415  VAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGI 474
                G       QG        G+   D ++G+      +G   ED   G   +  V+G 
Sbjct: 613  PGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG---EDGFPGFKGDIGVKGD 669

Query: 475  ANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGI---ATEDVADGIANE 531
              E  V G   E    G   +        P    G   ++   G+          G    
Sbjct: 670  RGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGF 729

Query: 532  DAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGV 591
                G + E  A G++ +        P    G   +   +G   +  A G +  D  HG 
Sbjct: 730  PGFPGASGEKGARGLSGKSGPRGERGPTGPRG---QRGPRGATGKSGAKGTSGGDGPHGP 786

Query: 592  ANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDAL 651
              E  + G    +   G        G        G   EV   G        GVV     
Sbjct: 787  PGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQG- 845

Query: 652  HGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISK 711
                A E             G   E    G A ++  +G      A G        G   
Sbjct: 846  ---AAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPG 902

Query: 712  EDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQG 771
            E  + G A     +G        G A      G A      G       QG       +G
Sbjct: 903  ERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKG 962

Query: 772  VANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDA 831
            V  E    G    D VQG        G+       GVA ED  +G   +   +G      
Sbjct: 963  VPGEKGPIGPTGRDGVQGPV------GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKG 1016

Query: 832  VHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIA 891
             HG        G   +  A G   E   +G       H     ++  +    P    G+ 
Sbjct: 1017 EHGPPGPPGPIGPVGQPGAAGADGEPGARGPQG----HFGAKGDEGTRGFNGPPGPIGL- 1071

Query: 892  NEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANE 951
             +G+      +G  T DV          G       +  A  + A          G    
Sbjct: 1072 -QGLPGPSGEKG-ETGDV-------GPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGP 1122

Query: 952  DAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGI 1011
                G   E  + G+  E   +G   E    G   E    G       +G    D  +G 
Sbjct: 1123 PGEKGEPGESGSPGIQGEPGVKGPRGE---RGEKGESGQPGEPGPPGPKGPTGDDGPKGN 1179

Query: 1012 ANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAA 1071
                   G        G   +D A+G   ED   G        G +      G      +
Sbjct: 1180 PGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS 1239

Query: 1072 QGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANE 1131
             G       +G   +    G   +    G A      G      + G   +    G   +
Sbjct: 1240 PGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQ 1299

Query: 1132 VEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGI 1191
                G      + G+  +  A G        G+      QG   E   +G+       G 
Sbjct: 1300 AGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQG---EKGDRGLPGPQGSPGQ 1356

Query: 1192 ANEDAVHGVAKEVAAHG 1208
              E  + G +  +   G
Sbjct: 1357 KGEMGIPGASGPIGPGG 1373



 Score = 85.5 bits (210), Expect = 6e-16
 Identities = 192/1049 (18%), Positives = 293/1049 (27%), Gaps = 76/1049 (7%)

Query: 67   GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126
            G T      G       +G + +    G        G   +   +G A    A+G+  + 
Sbjct: 407  GYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDP 466

Query: 127  AVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIA 186
             V+G    D + G+  E   +G        G   ED  +G   E   + +  E   + + 
Sbjct: 467  GVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLL 526

Query: 187  NEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQ 246
                  GI     V+G+      +G        G   +    G       QG       +
Sbjct: 527  GPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEK 586

Query: 247  GVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 306
            G   +  + G+   D   G   +    G        G       QG       +G+   D
Sbjct: 587  GPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSG------PQGPLGYPGPRGVKGVD 640

Query: 307  AVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVA 366
             + G+       G   ED            G   EV   G   ED  +G        G  
Sbjct: 641  GIRGLK---GHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTG-- 695

Query: 367  KEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAA 426
             +    G+  E    GV     L G    +    ++  P    G + E  A G++ +   
Sbjct: 696  -DPGPPGLMGEKGKLGV---PGLPGYPGRQGPKGSLGFP-GFPGASGEKGARGLSGKSGP 750

Query: 427  QGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKE 486
            +G        G   +   +G   +  A+G +  D   G   E   +G+      +G    
Sbjct: 751  RGERGPTGPRG---QRGPRGATGKSGAKGTSGGDGPHGPPGE---RGLPGPQGPNGFPGP 804

Query: 487  VAAHGVANKDA--AHAIAKPDAA-------RGIANEVAAQGIATEDVADGIANEDAVHGV 537
                G   KD    H   + +          G    V  QG A E    G        G 
Sbjct: 805  KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGP 864

Query: 538  ANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAV 597
              E    G A ++       P  A G       +G   E    G A      G       
Sbjct: 865  PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP 924

Query: 598  HGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVAN 657
             G A     +G A      G       QG        GV  E    G    D + G V  
Sbjct: 925  PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPV-- 982

Query: 658  EDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQG 717
                          G+       G+A ED  +G   +   +G       HG        G
Sbjct: 983  --------------GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIG 1028

Query: 718  IANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVE 777
               +  A G   E   +G        G       +G      +QG+      +G   +V 
Sbjct: 1029 PVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVG 1088

Query: 778  VQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVAN 837
              G       +G A  + A G        G       +G   E  + G+  E  V G   
Sbjct: 1089 PMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRG 1148

Query: 838  EDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVAN 897
            E   +G +      G   E    G        G   N      +  P         G   
Sbjct: 1149 ERGEKGES------GQPGEPGPPGPKGPTGDDGPKGNPG---PVGFPGDPGPPGEGGPRG 1199

Query: 898  EVAAQGIATEDVADGIAKDAAHGITKEEAAQA-IAKQDAAHSITNE--DAAQGVANEDAA 954
            +  A+G   ED   G  +  + G T E      + K+  A S  +E     +G   +  A
Sbjct: 1200 QDGAKGDRGEDGEPG--QPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGA 1257

Query: 955  HGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANE 1014
             G   +    G A      G      + G   +    G   +    G      + G+  +
Sbjct: 1258 IGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGD 1317

Query: 1015 DAAH------GIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGIS------KEDAV 1062
              A       G+   +   G   E   +G+     + G   E+   G S          +
Sbjct: 1318 AGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGL 1377

Query: 1063 QGIANEDAAQGIANEDAAQGIAHEDAVQG 1091
             G A    A+G       +G   E  VQG
Sbjct: 1378 PGPAGPKGAKGATGPGGPKG---EKGVQG 1403



 Score = 75.5 bits (184), Expect = 6e-13
 Identities = 153/878 (17%), Positives = 231/878 (26%), Gaps = 40/878 (4%)

Query: 1413 VQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQ---- 1468
            V+G    +   G+       G    V   G        G+   D A G      +     
Sbjct: 311  VEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRF 370

Query: 1469 GIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANED 1528
            G    D    VA + A      + A  A+  P    G        G        G + + 
Sbjct: 371  GSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDL 430

Query: 1529 AAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVV 1588
               G        G   +    G A  D  +G+  +    G    D + G+  E       
Sbjct: 431  GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRG-- 488

Query: 1589 ANEDAAQAIAKP---DAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKE 1645
              +  AQ +  P   D   G   E+    +  +   +G+       GI       G+   
Sbjct: 489  --DTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGP 546

Query: 1646 DAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGV 1705
               +G        G   +    G       QG        G   +    G+   D   G 
Sbjct: 547  QGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH 606

Query: 1706 ANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAV 1765
              ++   G        G        G        GI       G   ED   G   +  V
Sbjct: 607  PGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGV 666

Query: 1766 QGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNE 1825
            +G   E  V     E    G            P    G   ++   G+       G P  
Sbjct: 667  KGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLP------GYPGR 720

Query: 1826 DAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGI 1885
                G        G S E   +G++ +   +G   E    G   +   +G   +   +G 
Sbjct: 721  QGPKGSLGFPGFPGASGEKGARGLSGKSGPRG---ERGPTGPRGQRGPRGATGKSGAKGT 777

Query: 1886 ANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAV 1945
            +  D  HG   E   +G+                G   +D + G   Q    G   +   
Sbjct: 778  SGGDGPHGPPGE---RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGP 834

Query: 1946 QGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANE 2005
             G       QG A E    G        G   E    G A ++  +G   +    G   +
Sbjct: 835  PGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKG---DPGPPGAPGK 891

Query: 2006 DAAHAIAKPDAARGIANEVAAQGIATEDVADG------IANEDAAHGVANEDAAQAIAKP 2059
            D    +      RG+       G+   +   G         E  A G            P
Sbjct: 892  DGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGP 951

Query: 2060 DAAHGIANE-GIATEDVADG-IAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNE 2117
                G A E G+  E    G    D VQG         +       G+  ED  +G   +
Sbjct: 952  QGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVG------LPGPAGPPGVAGEDGDKGEVGD 1005

Query: 2118 VAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGI 2177
               +G       HG        G   +  A G   E  A+G       +G        G 
Sbjct: 1006 PGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGP 1065

Query: 2178 AHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAV 2237
                 +QG+      +G   +V   G       +G A    A G        G       
Sbjct: 1066 PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGE 1125

Query: 2238 HGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVHG 2275
             G   E  +  +  E   +G   E    G + +    G
Sbjct: 1126 KGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPG 1163



 Score = 56.6 bits (135), Expect = 3e-07
 Identities = 85/483 (17%), Positives = 132/483 (27%), Gaps = 13/483 (2%)

Query: 1798 PDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQG 1857
            P    G   +   +G A  D A G+P +    G        G+  E   +G        G
Sbjct: 438  PQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPG 497

Query: 1858 IAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAN--- 1914
               ED  +G   E+  +G+  E   +G+       GI      +G+      +       
Sbjct: 498  PPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQG 557

Query: 1915 EDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQG 1974
            E    G       QG+     A G   E   QG        G        G       +G
Sbjct: 558  EPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKG 617

Query: 1975 IANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDV 2034
                   QG       +G+   D + G+            D   G   ++  +G   E  
Sbjct: 618  NQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG---EDGFPGFKGDIGVKGDRGEVG 674

Query: 2035 ADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQ 2094
              G   ED   G            P    G   + +    +         +G        
Sbjct: 675  VPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK-LGVPGLPGYPGRQGPKGSLGFPGFP 733

Query: 2095 AIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEV 2154
              + +  A G++ +   +G   E    G   +    G   +  A G +  D   G   E 
Sbjct: 734  GASGEKGARGLSGKSGPRG---ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGE- 789

Query: 2155 AAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVA 2214
              +G+       G        G   KD + G   +    G   +    G       QG A
Sbjct: 790  --RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAA 847

Query: 2215 NEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVH 2274
             E    G        G   E  + G A ++  +       A G        G   E  + 
Sbjct: 848  GETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLP 907

Query: 2275 GIA 2277
            G A
Sbjct: 908  GTA 910



 Score = 37.7 bits (86), Expect = 0.14
 Identities = 73/380 (19%), Positives = 103/380 (27%), Gaps = 34/380 (8%)

Query: 1927 VQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQ---- 1982
            V+G    +   G+     +QG        G        G+   D A G            
Sbjct: 311  VEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRF 370

Query: 1983 GIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANED 2042
            G    D    +A ++A      + A  A+  P    G        G   +  + G+  E 
Sbjct: 371  GSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLG---QPGSPGLKGES 427

Query: 2043 AAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAED----------AVQGITNEEA 2092
               G       Q +  P    G    G A  D A G+  D           + G+  E+ 
Sbjct: 428  GDLGPQGPRGPQGLTGPPGKAG--RRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKG 485

Query: 2093 AQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANE------DA 2146
             +         G   ED  +G   E+  +G+  E    G+       G+         D 
Sbjct: 486  HRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDG 545

Query: 2147 AQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVAN 2206
             QG    +  QG       QG       QG+       G   E   QG        G   
Sbjct: 546  PQGPKGSLGPQGEPGPPGQQGTPG---TQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG 602

Query: 2207 EDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAK------EDAAQGIAN 2260
                 G       +G       QG        GV   D  R +        ED   G   
Sbjct: 603  PPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKG 662

Query: 2261 EDAAHGIANEDAVHGIANED 2280
            +    G   E  V G   ED
Sbjct: 663  DIGVKGDRGEVGVPGSRGED 682


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 99.8 bits (247), Expect = 3e-20
 Identities = 204/1077 (18%), Positives = 301/1077 (27%), Gaps = 68/1077 (6%)

Query: 923  KEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVH 982
            +E  AQAI +Q A  ++       G+       G      A+G + +   QG        
Sbjct: 524  QEAQAQAILQQ-ARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPP 582

Query: 983  GVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANED 1042
            G   +   +G       +G+  +   +G    D   G+  +    G        G   +D
Sbjct: 583  GPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDD 642

Query: 1043 AAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVA 1102
              +G   E+   G+  E   +G+       G   +             G+A  D   G  
Sbjct: 643  GMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQ------------PGMAGVDGPPGPK 690

Query: 1103 KEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAH 1162
              +   G       QG      + G    +   G        G+A    A G        
Sbjct: 691  GNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKE 750

Query: 1163 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPD 1222
            G + E  A G       QG       +G+   D V G+     + G   ED         
Sbjct: 751  GQSGEKGALG---PPGPQGPIGYPGPRGVKGADGVRGLK---GSKGEKGEDGFPGFKGDM 804

Query: 1223 AARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIA 1282
              +G   EV   G   ED  +G        G        G   +  V G+      QG  
Sbjct: 805  GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 864

Query: 1283 KEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAH 1342
                  G    +  +G       +GVA +   +G       +G       +G   +    
Sbjct: 865  GSTGFPGFPGANGEKG------ARGVAGKPGPRGQRGPTGPRG---SRGARGPTGKPGPK 915

Query: 1343 GIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANED 1402
            G +  D   G   E   Q         G        G   +D   G   +    G   + 
Sbjct: 916  GTSGGDGPPGPPGERGPQ---GPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKT 972

Query: 1403 AVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIA 1462
               G    V  QG   E    G        G   E    G A ++ A+G   +   QGI+
Sbjct: 973  GPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKG---DPGPQGIS 1029

Query: 1463 HEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVAD 1522
             +D   G+       G+     A G+   +       P  + G      T G        
Sbjct: 1030 GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAG------PI 1083

Query: 1523 GIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVA---NEDAVQGVV 1579
            G+       G       +G   E    G A  D VQG V      G A    ED  +G +
Sbjct: 1084 GLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEI 1143

Query: 1580 NEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAA 1639
             E        ++        P    G+   V A  IA  D   G   Q    G   +  A
Sbjct: 1144 GEPGQKGSKGDKGE----NGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGA 1199

Query: 1640 HGISKEDAVQGIANEDAAQGIANED---------------AAQGIAHEDAVQG-IANEDA 1683
             G        G+       G   E+                 QG    D  QG   +  +
Sbjct: 1200 RGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGS 1259

Query: 1684 VHGVAKEVAAHGVANEDP--VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGI 1741
            V GV ++       N  P    GV      +G   E    G A     +G   +D   G 
Sbjct: 1260 VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1319

Query: 1742 TNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAA 1801
               V   G        G A +D V G   ED            G A          P  A
Sbjct: 1320 PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGA 1379

Query: 1802 RGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKE 1861
             G       +G   E  A+G P +    G        G      + G   E    G A +
Sbjct: 1380 AGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQ 1439

Query: 1862 DPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGI 1921
            D   G      + G+  +   +G        G+      QG   E   + +     + G 
Sbjct: 1440 DGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG---EKGDRGLPGTQGSPGA 1496

Query: 1922 SKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANE 1978
              +  + G A      G       QG      + G A +    G+     + G   E
Sbjct: 1497 KGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGE 1553



 Score = 84.7 bits (208), Expect = 1e-15
 Identities = 195/1024 (19%), Positives = 295/1024 (28%), Gaps = 72/1024 (7%)

Query: 1262 GISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEV 1321
            G++      G      A+G + +   QG        G   +   +G    D  +G+  E 
Sbjct: 547  GLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEP 606

Query: 1322 EVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIA 1381
              +G    D + G+  +    G        G   +D  +    E   +G+  E   +G+ 
Sbjct: 607  GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLL 666

Query: 1382 NEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAH 1441
                  G   +    G+A  D   G    +  QG       QG        G    +   
Sbjct: 667  GPRGTPGAPGQP---GMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPP 723

Query: 1442 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPD 1501
            G        G+A    A G       +G + E    G        G         +   D
Sbjct: 724  GEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPP---GPQGPIGYPGPRGVKGAD 780

Query: 1502 AARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVV 1561
              RG+      +G            ED   G   ++  +G   EV   G   ED  +G  
Sbjct: 781  GVRGLKGSKGEKG------------EDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPK 828

Query: 1562 KEVTAHG---VANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANK 1618
                  G    + +   +G +    L      +    +   P    G   E  A  +A K
Sbjct: 829  GRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFP-GANGEKGARGVAGK 887

Query: 1619 DAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGI 1678
               +G   Q    G      A G + +   +G +  D   G   E   QG        G 
Sbjct: 888  PGPRG---QRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP 944

Query: 1679 ANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAA 1738
                   G        G   E   QG        GV   V  QG   E    G       
Sbjct: 945  KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGV---VGPQGPTGETGPIGERGHPGP 1001

Query: 1739 HGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKP 1798
             G   E    G A ++ A+G   +   QGI+ +D    +       G+     A  +   
Sbjct: 1002 PGPPGEQGLPGAAGKEGAKG---DPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1058

Query: 1799 DAARGIANEVAA---QGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAA 1855
            +  +G    V +   +G A      G+P      G        G   E   QG A  D  
Sbjct: 1059 EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGV 1118

Query: 1856 QGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANE 1915
            QG     P+ G+       G   ED  +G   E    G   +    G             
Sbjct: 1119 QG-----PV-GLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG------------P 1160

Query: 1916 DAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGI 1975
                G+       GIA  D   G   +  + G   ++ A+G        G+      QG+
Sbjct: 1161 PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGL------QGL 1214

Query: 1976 ANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVA 2035
                  +G   +    G        G    + A     P  + G    V  +G   E   
Sbjct: 1215 PGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGN 1274

Query: 2036 DGIANEDAAHGVANEDAAQAIAKPDAAHGIAN-EGIATEDVADGIAEDA-VQGITNEEAA 2093
             G   E    G   E   +  A P  A G    +G   +D   G        G       
Sbjct: 1275 PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1334

Query: 2094 QAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANE 2153
               A QD   G   ED   G   +    G + E    G   +    G A  +  QG   E
Sbjct: 1335 PGPAGQDGVGGDKGEDGDPG---QPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQG---E 1388

Query: 2154 VAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGV 2213
              A+G A  +   G    V  QG A K   +G+       G   E    G A +D   G 
Sbjct: 1389 KGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLR---GIPGPVGEQGLPGAAGQDGPPGP 1445

Query: 2214 ANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAV 2273
                   G+  +  ++G      + G+      +    E   +G+     + G   +  +
Sbjct: 1446 MGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQ---GEKGDRGLPGTQGSPGAKGDGGI 1502

Query: 2274 HGIA 2277
             G A
Sbjct: 1503 PGPA 1506



 Score = 81.6 bits (200), Expect = 8e-15
 Identities = 173/978 (17%), Positives = 260/978 (26%), Gaps = 58/978 (5%)

Query: 1318 ANEVEVQGVAHEDAV--------QGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQ 1369
            A E + Q +  +  +         G+       G      A+G + +   Q         
Sbjct: 523  AQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPP 582

Query: 1370 GISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANED 1429
            G + +   +G    D  +G+  E   +G    D + G+  +   +G        G   +D
Sbjct: 583  GPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDD 642

Query: 1430 AAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVA 1489
               G   E+   G+  E   +G+       G   +  + G+   D   G    +   G  
Sbjct: 643  GMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGV---DGPPGPKGNMGPQGEP 699

Query: 1490 NEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVH 1549
                      P    G    +   G        G+A    A G       +G + E    
Sbjct: 700  GPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL 759

Query: 1550 GVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANE 1609
            G       QG +      GV   D V+G+            ED            G   E
Sbjct: 760  G---PPGPQGPIGYPGPRGVKGADGVRGLKGSKG----EKGEDGFPGFKGDMGLKGDRGE 812

Query: 1610 VAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGI 1669
            V       +D  +G       +G A      G S +   +G        G       +G 
Sbjct: 813  VGQIGPRGEDGPEG------PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGS 866

Query: 1670 AHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAV 1729
                   G   E    GVA +    G       +G       +G   +   +G +  D  
Sbjct: 867  TGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRG---SRGARGPTGKPGPKGTSGGDGP 923

Query: 1730 QGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANE 1789
             G   E    G    V   G        G   +D + G   +        E    G    
Sbjct: 924  PGPPGERGPQGPQGPV---GFPGPKGPPGPPGKDGLPGHPGQRG------ETGFQGKTGP 974

Query: 1790 DAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGI 1849
                 +  P    G    +  +G        G P E    G A +  A G      + G 
Sbjct: 975  PGPGGVVGPQGPTGETGPIGERG---HPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 1031

Query: 1850 ANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAA 1909
                  +G   E  + G      ++G        G        G A      G+      
Sbjct: 1032 DGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGP 1091

Query: 1910 QDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANE 1969
            Q        +G   E   QG A +D  QG        G A      G   E+   G    
Sbjct: 1092 QGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGS 1151

Query: 1970 DAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGI---ANEVAA 2026
               +G        G+       GIA  D   G   +         + ARG       +  
Sbjct: 1152 KGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGL 1211

Query: 2027 QGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQG 2086
            QG+       G   +    G       +    P+ A G      +   V  G+ E    G
Sbjct: 1212 QGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVG-GVGEKGEPG 1270

Query: 2087 ITNE---EAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVAN 2143
                        +       G   E    G      A+G   +D   G    V   G   
Sbjct: 1271 EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPG 1330

Query: 2144 EDAAQGVANEVAAQGVANED------AVQGVANEVEVQGIAHKDAIQGIANEDAAQGVAN 2197
                 G A +    G   ED         G + E    G   K    G A  +  QG   
Sbjct: 1331 PPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQG--- 1387

Query: 2198 EVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQG 2257
            E  A G A  +   G    V  QG A +   +G+     + G   E      A +D   G
Sbjct: 1388 EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLR---GIPGPVGEQGLPGAAGQDGPPG 1444

Query: 2258 IANEDAAHGIANEDAVHG 2275
                    G+  +    G
Sbjct: 1445 PMGPPGLPGLKGDPGSKG 1462



 Score = 75.5 bits (184), Expect = 6e-13
 Identities = 192/1044 (18%), Positives = 288/1044 (27%), Gaps = 76/1044 (7%)

Query: 67   GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126
            G+T      G      A+G + +    G        G   +   +G       +G+  E 
Sbjct: 547  GLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEP 606

Query: 127  AVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIA 186
              +G    D + G+  +   +G        G   +D  +G   E   + +  E   + + 
Sbjct: 607  GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLL 666

Query: 187  NEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQ 246
                  G   +    G+A  D   G       QG       QG      + G    +   
Sbjct: 667  GPRGTPGAPGQ---PGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPP 723

Query: 247  GVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 306
            G        G+A    A G        G + E  A G       QG       +G+   D
Sbjct: 724  GEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALG---PPGPQGPIGYPGPRGVKGAD 780

Query: 307  AVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVA 366
             V G+     + G   ED            G   EV   G   ED  +G        G A
Sbjct: 781  GVRGLK---GSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEG------PKGRA 831

Query: 367  KEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAA 426
                  G + +   +G +    L G    +    +   P    G   E  A G+A +   
Sbjct: 832  GPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP-GFPGANGEKGARGVAGKPGP 890

Query: 427  QGIANEV------AAHGISKEDAVQGIANEDAAQGIAHEDAAQ------GIAHEDAVQGI 474
            +G            A G + +   +G +  D   G   E   Q      G        G 
Sbjct: 891  RGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGP 950

Query: 475  ANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAV 534
              +D + G   +    G   K            +G   E    G        G   E  +
Sbjct: 951  PGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGL 1010

Query: 535  HGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANE 594
             G A +  A G   +     I+  D   G+      +G+     A G+   +   G    
Sbjct: 1011 PGAAGKEGAKG---DPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGP 1067

Query: 595  VAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGV 654
            V   G       +G A      G+      QG        G   E   QG    D + G 
Sbjct: 1068 VGSPG------ERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1121

Query: 655  VANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDA 714
            V     A     P    G   E+   G       +G        G+   V A GI+  D 
Sbjct: 1122 VGLPGPAGPAGSP-GEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDG 1180

Query: 715  VQGIANEDAAQGIAHEDAVQGI---------------ANEDAVHGVAKEVAAHGVANEDP 759
              G   +    G   ++  +G                  E   +G    +   G      
Sbjct: 1181 EPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRG 1240

Query: 760  VQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVAN 819
             QG    D  QG    V   G   E    G A      G A      GV      +G   
Sbjct: 1241 PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEA------GVGGPKGERGEKG 1294

Query: 820  EDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQ 879
            E    G A      G   +D  +G    V   G        G   ++ + G    ED   
Sbjct: 1295 EAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGG-DKGEDGDP 1353

Query: 880  AIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSI 939
                P         G + E    G   +    G A   A G   E+ A+  A  +     
Sbjct: 1354 GQPGP--------PGPSGEAGPPGPPGKRGPPGAA--GAEGRQGEKGAKGEAGAEGPPGK 1403

Query: 940  TNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEV 999
            T     QG A +    G+       G   E    G A +D   G      + G+  +   
Sbjct: 1404 TGPVGPQGPAGKPGPEGLR---GIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGS 1460

Query: 1000 QGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKE 1059
            +G      + G+       G   E    G+     + G   +    G A  +   G    
Sbjct: 1461 KGEKGHPGLIGLIGPPGEQG---EKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL 1517

Query: 1060 DAVQGIANEDAAQGIANEDAAQGI 1083
               QG      + G A +    G+
Sbjct: 1518 PGPQGPKGNKGSTGPAGQKGDSGL 1541


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score = 99.8 bits (247), Expect = 3e-20
 Identities = 204/1077 (18%), Positives = 301/1077 (27%), Gaps = 68/1077 (6%)

Query: 923  KEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVH 982
            +E  AQAI +Q A  ++       G+       G      A+G + +   QG        
Sbjct: 473  QEAQAQAILQQ-ARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPP 531

Query: 983  GVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANED 1042
            G   +   +G       +G+  +   +G    D   G+  +    G        G   +D
Sbjct: 532  GPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDD 591

Query: 1043 AAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVA 1102
              +G   E+   G+  E   +G+       G   +             G+A  D   G  
Sbjct: 592  GMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQ------------PGMAGVDGPPGPK 639

Query: 1103 KEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAH 1162
              +   G       QG      + G    +   G        G+A    A G        
Sbjct: 640  GNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKE 699

Query: 1163 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPD 1222
            G + E  A G       QG       +G+   D V G+     + G   ED         
Sbjct: 700  GQSGEKGALG---PPGPQGPIGYPGPRGVKGADGVRGLK---GSKGEKGEDGFPGFKGDM 753

Query: 1223 AARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIA 1282
              +G   EV   G   ED  +G        G        G   +  V G+      QG  
Sbjct: 754  GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 813

Query: 1283 KEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAH 1342
                  G    +  +G       +GVA +   +G       +G       +G   +    
Sbjct: 814  GSTGFPGFPGANGEKG------ARGVAGKPGPRGQRGPTGPRG---SRGARGPTGKPGPK 864

Query: 1343 GIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANED 1402
            G +  D   G   E   Q         G        G   +D   G   +    G   + 
Sbjct: 865  GTSGGDGPPGPPGERGPQ---GPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKT 921

Query: 1403 AVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIA 1462
               G    V  QG   E    G        G   E    G A ++ A+G   +   QGI+
Sbjct: 922  GPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKG---DPGPQGIS 978

Query: 1463 HEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVAD 1522
             +D   G+       G+     A G+   +       P  + G      T G        
Sbjct: 979  GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAG------PI 1032

Query: 1523 GIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVA---NEDAVQGVV 1579
            G+       G       +G   E    G A  D VQG V      G A    ED  +G +
Sbjct: 1033 GLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEI 1092

Query: 1580 NEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAA 1639
             E        ++        P    G+   V A  IA  D   G   Q    G   +  A
Sbjct: 1093 GEPGQKGSKGDKGE----NGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGA 1148

Query: 1640 HGISKEDAVQGIANEDAAQGIANED---------------AAQGIAHEDAVQG-IANEDA 1683
             G        G+       G   E+                 QG    D  QG   +  +
Sbjct: 1149 RGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGS 1208

Query: 1684 VHGVAKEVAAHGVANEDP--VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGI 1741
            V GV ++       N  P    GV      +G   E    G A     +G   +D   G 
Sbjct: 1209 VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1268

Query: 1742 TNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAA 1801
               V   G        G A +D V G   ED            G A          P  A
Sbjct: 1269 PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGA 1328

Query: 1802 RGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKE 1861
             G       +G   E  A+G P +    G        G      + G   E    G A +
Sbjct: 1329 AGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQ 1388

Query: 1862 DPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGI 1921
            D   G      + G+  +   +G        G+      QG   E   + +     + G 
Sbjct: 1389 DGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG---EKGDRGLPGTQGSPGA 1445

Query: 1922 SKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANE 1978
              +  + G A      G       QG      + G A +    G+     + G   E
Sbjct: 1446 KGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGE 1502



 Score = 84.7 bits (208), Expect = 1e-15
 Identities = 195/1024 (19%), Positives = 295/1024 (28%), Gaps = 72/1024 (7%)

Query: 1262 GISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEV 1321
            G++      G      A+G + +   QG        G   +   +G    D  +G+  E 
Sbjct: 496  GLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEP 555

Query: 1322 EVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIA 1381
              +G    D + G+  +    G        G   +D  +    E   +G+  E   +G+ 
Sbjct: 556  GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLL 615

Query: 1382 NEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAH 1441
                  G   +    G+A  D   G    +  QG       QG        G    +   
Sbjct: 616  GPRGTPGAPGQP---GMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPP 672

Query: 1442 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPD 1501
            G        G+A    A G       +G + E    G        G         +   D
Sbjct: 673  GEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPP---GPQGPIGYPGPRGVKGAD 729

Query: 1502 AARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVV 1561
              RG+      +G            ED   G   ++  +G   EV   G   ED  +G  
Sbjct: 730  GVRGLKGSKGEKG------------EDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPK 777

Query: 1562 KEVTAHG---VANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANK 1618
                  G    + +   +G +    L      +    +   P    G   E  A  +A K
Sbjct: 778  GRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFP-GANGEKGARGVAGK 836

Query: 1619 DAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGI 1678
               +G   Q    G      A G + +   +G +  D   G   E   QG        G 
Sbjct: 837  PGPRG---QRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP 893

Query: 1679 ANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAA 1738
                   G        G   E   QG        GV   V  QG   E    G       
Sbjct: 894  KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGV---VGPQGPTGETGPIGERGHPGP 950

Query: 1739 HGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKP 1798
             G   E    G A ++ A+G   +   QGI+ +D    +       G+     A  +   
Sbjct: 951  PGPPGEQGLPGAAGKEGAKG---DPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1007

Query: 1799 DAARGIANEVAA---QGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAA 1855
            +  +G    V +   +G A      G+P      G        G   E   QG A  D  
Sbjct: 1008 EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGV 1067

Query: 1856 QGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANE 1915
            QG     P+ G+       G   ED  +G   E    G   +    G             
Sbjct: 1068 QG-----PV-GLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG------------P 1109

Query: 1916 DAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGI 1975
                G+       GIA  D   G   +  + G   ++ A+G        G+      QG+
Sbjct: 1110 PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGL------QGL 1163

Query: 1976 ANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVA 2035
                  +G   +    G        G    + A     P  + G    V  +G   E   
Sbjct: 1164 PGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGN 1223

Query: 2036 DGIANEDAAHGVANEDAAQAIAKPDAAHGIAN-EGIATEDVADGIAEDA-VQGITNEEAA 2093
             G   E    G   E   +  A P  A G    +G   +D   G        G       
Sbjct: 1224 PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1283

Query: 2094 QAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANE 2153
               A QD   G   ED   G   +    G + E    G   +    G A  +  QG   E
Sbjct: 1284 PGPAGQDGVGGDKGEDGDPG---QPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQG---E 1337

Query: 2154 VAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGV 2213
              A+G A  +   G    V  QG A K   +G+       G   E    G A +D   G 
Sbjct: 1338 KGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLR---GIPGPVGEQGLPGAAGQDGPPGP 1394

Query: 2214 ANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAV 2273
                   G+  +  ++G      + G+      +    E   +G+     + G   +  +
Sbjct: 1395 MGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQ---GEKGDRGLPGTQGSPGAKGDGGI 1451

Query: 2274 HGIA 2277
             G A
Sbjct: 1452 PGPA 1455



 Score = 81.6 bits (200), Expect = 8e-15
 Identities = 173/978 (17%), Positives = 260/978 (26%), Gaps = 58/978 (5%)

Query: 1318 ANEVEVQGVAHEDAV--------QGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQ 1369
            A E + Q +  +  +         G+       G      A+G + +   Q         
Sbjct: 472  AQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPP 531

Query: 1370 GISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANED 1429
            G + +   +G    D  +G+  E   +G    D + G+  +   +G        G   +D
Sbjct: 532  GPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDD 591

Query: 1430 AAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVA 1489
               G   E+   G+  E   +G+       G   +  + G+   D   G    +   G  
Sbjct: 592  GMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGV---DGPPGPKGNMGPQGEP 648

Query: 1490 NEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVH 1549
                      P    G    +   G        G+A    A G       +G + E    
Sbjct: 649  GPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL 708

Query: 1550 GVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANE 1609
            G       QG +      GV   D V+G+            ED            G   E
Sbjct: 709  G---PPGPQGPIGYPGPRGVKGADGVRGLKGSKG----EKGEDGFPGFKGDMGLKGDRGE 761

Query: 1610 VAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGI 1669
            V       +D  +G       +G A      G S +   +G        G       +G 
Sbjct: 762  VGQIGPRGEDGPEG------PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGS 815

Query: 1670 AHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAV 1729
                   G   E    GVA +    G       +G       +G   +   +G +  D  
Sbjct: 816  TGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRG---SRGARGPTGKPGPKGTSGGDGP 872

Query: 1730 QGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANE 1789
             G   E    G    V   G        G   +D + G   +        E    G    
Sbjct: 873  PGPPGERGPQGPQGPV---GFPGPKGPPGPPGKDGLPGHPGQRG------ETGFQGKTGP 923

Query: 1790 DAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGI 1849
                 +  P    G    +  +G        G P E    G A +  A G      + G 
Sbjct: 924  PGPGGVVGPQGPTGETGPIGERG---HPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 980

Query: 1850 ANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAA 1909
                  +G   E  + G      ++G        G        G A      G+      
Sbjct: 981  DGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGP 1040

Query: 1910 QDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANE 1969
            Q        +G   E   QG A +D  QG        G A      G   E+   G    
Sbjct: 1041 QGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGS 1100

Query: 1970 DAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGI---ANEVAA 2026
               +G        G+       GIA  D   G   +         + ARG       +  
Sbjct: 1101 KGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGL 1160

Query: 2027 QGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQG 2086
            QG+       G   +    G       +    P+ A G      +   V  G+ E    G
Sbjct: 1161 QGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVG-GVGEKGEPG 1219

Query: 2087 ITNE---EAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVAN 2143
                        +       G   E    G      A+G   +D   G    V   G   
Sbjct: 1220 EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPG 1279

Query: 2144 EDAAQGVANEVAAQGVANED------AVQGVANEVEVQGIAHKDAIQGIANEDAAQGVAN 2197
                 G A +    G   ED         G + E    G   K    G A  +  QG   
Sbjct: 1280 PPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQG--- 1336

Query: 2198 EVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQG 2257
            E  A G A  +   G    V  QG A +   +G+     + G   E      A +D   G
Sbjct: 1337 EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLR---GIPGPVGEQGLPGAAGQDGPPG 1393

Query: 2258 IANEDAAHGIANEDAVHG 2275
                    G+  +    G
Sbjct: 1394 PMGPPGLPGLKGDPGSKG 1411



 Score = 75.5 bits (184), Expect = 6e-13
 Identities = 192/1044 (18%), Positives = 288/1044 (27%), Gaps = 76/1044 (7%)

Query: 67   GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126
            G+T      G      A+G + +    G        G   +   +G       +G+  E 
Sbjct: 496  GLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEP 555

Query: 127  AVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIA 186
              +G    D + G+  +   +G        G   +D  +G   E   + +  E   + + 
Sbjct: 556  GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLL 615

Query: 187  NEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQ 246
                  G   +    G+A  D   G       QG       QG      + G    +   
Sbjct: 616  GPRGTPGAPGQ---PGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPP 672

Query: 247  GVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 306
            G        G+A    A G        G + E  A G       QG       +G+   D
Sbjct: 673  GEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALG---PPGPQGPIGYPGPRGVKGAD 729

Query: 307  AVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVA 366
             V G+     + G   ED            G   EV   G   ED  +G        G A
Sbjct: 730  GVRGLK---GSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEG------PKGRA 780

Query: 367  KEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAA 426
                  G + +   +G +    L G    +    +   P    G   E  A G+A +   
Sbjct: 781  GPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP-GFPGANGEKGARGVAGKPGP 839

Query: 427  QGIANEV------AAHGISKEDAVQGIANEDAAQGIAHEDAAQ------GIAHEDAVQGI 474
            +G            A G + +   +G +  D   G   E   Q      G        G 
Sbjct: 840  RGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGP 899

Query: 475  ANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAV 534
              +D + G   +    G   K            +G   E    G        G   E  +
Sbjct: 900  PGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGL 959

Query: 535  HGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANE 594
             G A +  A G   +     I+  D   G+      +G+     A G+   +   G    
Sbjct: 960  PGAAGKEGAKG---DPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGP 1016

Query: 595  VAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGV 654
            V   G       +G A      G+      QG        G   E   QG    D + G 
Sbjct: 1017 VGSPG------ERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1070

Query: 655  VANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDA 714
            V     A     P    G   E+   G       +G        G+   V A GI+  D 
Sbjct: 1071 VGLPGPAGPAGSP-GEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDG 1129

Query: 715  VQGIANEDAAQGIAHEDAVQGI---------------ANEDAVHGVAKEVAAHGVANEDP 759
              G   +    G   ++  +G                  E   +G    +   G      
Sbjct: 1130 EPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRG 1189

Query: 760  VQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVAN 819
             QG    D  QG    V   G   E    G A      G A      GV      +G   
Sbjct: 1190 PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEA------GVGGPKGERGEKG 1243

Query: 820  EDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQ 879
            E    G A      G   +D  +G    V   G        G   ++ + G    ED   
Sbjct: 1244 EAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGG-DKGEDGDP 1302

Query: 880  AIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSI 939
                P         G + E    G   +    G A   A G   E+ A+  A  +     
Sbjct: 1303 GQPGP--------PGPSGEAGPPGPPGKRGPPGAA--GAEGRQGEKGAKGEAGAEGPPGK 1352

Query: 940  TNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEV 999
            T     QG A +    G+       G   E    G A +D   G      + G+  +   
Sbjct: 1353 TGPVGPQGPAGKPGPEGLR---GIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGS 1409

Query: 1000 QGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKE 1059
            +G      + G+       G   E    G+     + G   +    G A  +   G    
Sbjct: 1410 KGEKGHPGLIGLIGPPGEQG---EKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL 1466

Query: 1060 DAVQGIANEDAAQGIANEDAAQGI 1083
               QG      + G A +    G+
Sbjct: 1467 PGPQGPKGNKGSTGPAGQKGDSGL 1490


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 99.8 bits (247), Expect = 3e-20
 Identities = 204/1077 (18%), Positives = 301/1077 (27%), Gaps = 68/1077 (6%)

Query: 923  KEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVH 982
            +E  AQAI +Q A  ++       G+       G      A+G + +   QG        
Sbjct: 512  QEAQAQAILQQ-ARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPP 570

Query: 983  GVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANED 1042
            G   +   +G       +G+  +   +G    D   G+  +    G        G   +D
Sbjct: 571  GPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDD 630

Query: 1043 AAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVA 1102
              +G   E+   G+  E   +G+       G   +             G+A  D   G  
Sbjct: 631  GMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQ------------PGMAGVDGPPGPK 678

Query: 1103 KEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAH 1162
              +   G       QG      + G    +   G        G+A    A G        
Sbjct: 679  GNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKE 738

Query: 1163 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPD 1222
            G + E  A G       QG       +G+   D V G+     + G   ED         
Sbjct: 739  GQSGEKGALG---PPGPQGPIGYPGPRGVKGADGVRGLK---GSKGEKGEDGFPGFKGDM 792

Query: 1223 AARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIA 1282
              +G   EV   G   ED  +G        G        G   +  V G+      QG  
Sbjct: 793  GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 852

Query: 1283 KEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAH 1342
                  G    +  +G       +GVA +   +G       +G       +G   +    
Sbjct: 853  GSTGFPGFPGANGEKG------ARGVAGKPGPRGQRGPTGPRG---SRGARGPTGKPGPK 903

Query: 1343 GIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANED 1402
            G +  D   G   E   Q         G        G   +D   G   +    G   + 
Sbjct: 904  GTSGGDGPPGPPGERGPQ---GPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKT 960

Query: 1403 AVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIA 1462
               G    V  QG   E    G        G   E    G A ++ A+G   +   QGI+
Sbjct: 961  GPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKG---DPGPQGIS 1017

Query: 1463 HEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVAD 1522
             +D   G+       G+     A G+   +       P  + G      T G        
Sbjct: 1018 GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAG------PI 1071

Query: 1523 GIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVA---NEDAVQGVV 1579
            G+       G       +G   E    G A  D VQG V      G A    ED  +G +
Sbjct: 1072 GLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEI 1131

Query: 1580 NEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAA 1639
             E        ++        P    G+   V A  IA  D   G   Q    G   +  A
Sbjct: 1132 GEPGQKGSKGDKGE----NGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGA 1187

Query: 1640 HGISKEDAVQGIANEDAAQGIANED---------------AAQGIAHEDAVQG-IANEDA 1683
             G        G+       G   E+                 QG    D  QG   +  +
Sbjct: 1188 RGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGS 1247

Query: 1684 VHGVAKEVAAHGVANEDP--VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGI 1741
            V GV ++       N  P    GV      +G   E    G A     +G   +D   G 
Sbjct: 1248 VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1307

Query: 1742 TNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAA 1801
               V   G        G A +D V G   ED            G A          P  A
Sbjct: 1308 PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGA 1367

Query: 1802 RGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKE 1861
             G       +G   E  A+G P +    G        G      + G   E    G A +
Sbjct: 1368 AGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQ 1427

Query: 1862 DPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGI 1921
            D   G      + G+  +   +G        G+      QG   E   + +     + G 
Sbjct: 1428 DGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG---EKGDRGLPGTQGSPGA 1484

Query: 1922 SKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANE 1978
              +  + G A      G       QG      + G A +    G+     + G   E
Sbjct: 1485 KGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGE 1541



 Score = 84.7 bits (208), Expect = 1e-15
 Identities = 195/1024 (19%), Positives = 295/1024 (28%), Gaps = 72/1024 (7%)

Query: 1262 GISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEV 1321
            G++      G      A+G + +   QG        G   +   +G    D  +G+  E 
Sbjct: 535  GLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEP 594

Query: 1322 EVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIA 1381
              +G    D + G+  +    G        G   +D  +    E   +G+  E   +G+ 
Sbjct: 595  GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLL 654

Query: 1382 NEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAH 1441
                  G   +    G+A  D   G    +  QG       QG        G    +   
Sbjct: 655  GPRGTPGAPGQP---GMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPP 711

Query: 1442 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPD 1501
            G        G+A    A G       +G + E    G        G         +   D
Sbjct: 712  GEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPP---GPQGPIGYPGPRGVKGAD 768

Query: 1502 AARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVV 1561
              RG+      +G            ED   G   ++  +G   EV   G   ED  +G  
Sbjct: 769  GVRGLKGSKGEKG------------EDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPK 816

Query: 1562 KEVTAHG---VANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANK 1618
                  G    + +   +G +    L      +    +   P    G   E  A  +A K
Sbjct: 817  GRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFP-GANGEKGARGVAGK 875

Query: 1619 DAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGI 1678
               +G   Q    G      A G + +   +G +  D   G   E   QG        G 
Sbjct: 876  PGPRG---QRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP 932

Query: 1679 ANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAA 1738
                   G        G   E   QG        GV   V  QG   E    G       
Sbjct: 933  KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGV---VGPQGPTGETGPIGERGHPGP 989

Query: 1739 HGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKP 1798
             G   E    G A ++ A+G   +   QGI+ +D    +       G+     A  +   
Sbjct: 990  PGPPGEQGLPGAAGKEGAKG---DPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1046

Query: 1799 DAARGIANEVAA---QGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAA 1855
            +  +G    V +   +G A      G+P      G        G   E   QG A  D  
Sbjct: 1047 EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGV 1106

Query: 1856 QGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANE 1915
            QG     P+ G+       G   ED  +G   E    G   +    G             
Sbjct: 1107 QG-----PV-GLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG------------P 1148

Query: 1916 DAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGI 1975
                G+       GIA  D   G   +  + G   ++ A+G        G+      QG+
Sbjct: 1149 PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGL------QGL 1202

Query: 1976 ANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVA 2035
                  +G   +    G        G    + A     P  + G    V  +G   E   
Sbjct: 1203 PGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGN 1262

Query: 2036 DGIANEDAAHGVANEDAAQAIAKPDAAHGIAN-EGIATEDVADGIAEDA-VQGITNEEAA 2093
             G   E    G   E   +  A P  A G    +G   +D   G        G       
Sbjct: 1263 PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1322

Query: 2094 QAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANE 2153
               A QD   G   ED   G   +    G + E    G   +    G A  +  QG   E
Sbjct: 1323 PGPAGQDGVGGDKGEDGDPG---QPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQG---E 1376

Query: 2154 VAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGV 2213
              A+G A  +   G    V  QG A K   +G+       G   E    G A +D   G 
Sbjct: 1377 KGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLR---GIPGPVGEQGLPGAAGQDGPPGP 1433

Query: 2214 ANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAV 2273
                   G+  +  ++G      + G+      +    E   +G+     + G   +  +
Sbjct: 1434 MGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQ---GEKGDRGLPGTQGSPGAKGDGGI 1490

Query: 2274 HGIA 2277
             G A
Sbjct: 1491 PGPA 1494



 Score = 81.6 bits (200), Expect = 8e-15
 Identities = 173/978 (17%), Positives = 260/978 (26%), Gaps = 58/978 (5%)

Query: 1318 ANEVEVQGVAHEDAV--------QGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQ 1369
            A E + Q +  +  +         G+       G      A+G + +   Q         
Sbjct: 511  AQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPP 570

Query: 1370 GISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANED 1429
            G + +   +G    D  +G+  E   +G    D + G+  +   +G        G   +D
Sbjct: 571  GPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDD 630

Query: 1430 AAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVA 1489
               G   E+   G+  E   +G+       G   +  + G+   D   G    +   G  
Sbjct: 631  GMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGV---DGPPGPKGNMGPQGEP 687

Query: 1490 NEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVH 1549
                      P    G    +   G        G+A    A G       +G + E    
Sbjct: 688  GPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL 747

Query: 1550 GVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANE 1609
            G       QG +      GV   D V+G+            ED            G   E
Sbjct: 748  G---PPGPQGPIGYPGPRGVKGADGVRGLKGSKG----EKGEDGFPGFKGDMGLKGDRGE 800

Query: 1610 VAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGI 1669
            V       +D  +G       +G A      G S +   +G        G       +G 
Sbjct: 801  VGQIGPRGEDGPEG------PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGS 854

Query: 1670 AHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAV 1729
                   G   E    GVA +    G       +G       +G   +   +G +  D  
Sbjct: 855  TGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRG---SRGARGPTGKPGPKGTSGGDGP 911

Query: 1730 QGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANE 1789
             G   E    G    V   G        G   +D + G   +        E    G    
Sbjct: 912  PGPPGERGPQGPQGPV---GFPGPKGPPGPPGKDGLPGHPGQRG------ETGFQGKTGP 962

Query: 1790 DAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGI 1849
                 +  P    G    +  +G        G P E    G A +  A G      + G 
Sbjct: 963  PGPGGVVGPQGPTGETGPIGERG---HPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 1019

Query: 1850 ANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAA 1909
                  +G   E  + G      ++G        G        G A      G+      
Sbjct: 1020 DGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGP 1079

Query: 1910 QDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANE 1969
            Q        +G   E   QG A +D  QG        G A      G   E+   G    
Sbjct: 1080 QGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGS 1139

Query: 1970 DAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGI---ANEVAA 2026
               +G        G+       GIA  D   G   +         + ARG       +  
Sbjct: 1140 KGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGL 1199

Query: 2027 QGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQG 2086
            QG+       G   +    G       +    P+ A G      +   V  G+ E    G
Sbjct: 1200 QGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVG-GVGEKGEPG 1258

Query: 2087 ITNE---EAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVAN 2143
                        +       G   E    G      A+G   +D   G    V   G   
Sbjct: 1259 EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPG 1318

Query: 2144 EDAAQGVANEVAAQGVANED------AVQGVANEVEVQGIAHKDAIQGIANEDAAQGVAN 2197
                 G A +    G   ED         G + E    G   K    G A  +  QG   
Sbjct: 1319 PPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQG--- 1375

Query: 2198 EVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQG 2257
            E  A G A  +   G    V  QG A +   +G+     + G   E      A +D   G
Sbjct: 1376 EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLR---GIPGPVGEQGLPGAAGQDGPPG 1432

Query: 2258 IANEDAAHGIANEDAVHG 2275
                    G+  +    G
Sbjct: 1433 PMGPPGLPGLKGDPGSKG 1450



 Score = 75.5 bits (184), Expect = 6e-13
 Identities = 192/1044 (18%), Positives = 288/1044 (27%), Gaps = 76/1044 (7%)

Query: 67   GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126
            G+T      G      A+G + +    G        G   +   +G       +G+  E 
Sbjct: 535  GLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEP 594

Query: 127  AVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIA 186
              +G    D + G+  +   +G        G   +D  +G   E   + +  E   + + 
Sbjct: 595  GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLL 654

Query: 187  NEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQ 246
                  G   +    G+A  D   G       QG       QG      + G    +   
Sbjct: 655  GPRGTPGAPGQ---PGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPP 711

Query: 247  GVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 306
            G        G+A    A G        G + E  A G       QG       +G+   D
Sbjct: 712  GEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALG---PPGPQGPIGYPGPRGVKGAD 768

Query: 307  AVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVA 366
             V G+     + G   ED            G   EV   G   ED  +G        G A
Sbjct: 769  GVRGLK---GSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEG------PKGRA 819

Query: 367  KEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAA 426
                  G + +   +G +    L G    +    +   P    G   E  A G+A +   
Sbjct: 820  GPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP-GFPGANGEKGARGVAGKPGP 878

Query: 427  QGIANEV------AAHGISKEDAVQGIANEDAAQGIAHEDAAQ------GIAHEDAVQGI 474
            +G            A G + +   +G +  D   G   E   Q      G        G 
Sbjct: 879  RGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGP 938

Query: 475  ANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAV 534
              +D + G   +    G   K            +G   E    G        G   E  +
Sbjct: 939  PGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGL 998

Query: 535  HGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANE 594
             G A +  A G   +     I+  D   G+      +G+     A G+   +   G    
Sbjct: 999  PGAAGKEGAKG---DPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGP 1055

Query: 595  VAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGV 654
            V   G       +G A      G+      QG        G   E   QG    D + G 
Sbjct: 1056 VGSPG------ERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1109

Query: 655  VANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDA 714
            V     A     P    G   E+   G       +G        G+   V A GI+  D 
Sbjct: 1110 VGLPGPAGPAGSP-GEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDG 1168

Query: 715  VQGIANEDAAQGIAHEDAVQGI---------------ANEDAVHGVAKEVAAHGVANEDP 759
              G   +    G   ++  +G                  E   +G    +   G      
Sbjct: 1169 EPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRG 1228

Query: 760  VQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVAN 819
             QG    D  QG    V   G   E    G A      G A      GV      +G   
Sbjct: 1229 PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEA------GVGGPKGERGEKG 1282

Query: 820  EDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQ 879
            E    G A      G   +D  +G    V   G        G   ++ + G    ED   
Sbjct: 1283 EAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGG-DKGEDGDP 1341

Query: 880  AIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSI 939
                P         G + E    G   +    G A   A G   E+ A+  A  +     
Sbjct: 1342 GQPGP--------PGPSGEAGPPGPPGKRGPPGAA--GAEGRQGEKGAKGEAGAEGPPGK 1391

Query: 940  TNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEV 999
            T     QG A +    G+       G   E    G A +D   G      + G+  +   
Sbjct: 1392 TGPVGPQGPAGKPGPEGLR---GIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGS 1448

Query: 1000 QGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKE 1059
            +G      + G+       G   E    G+     + G   +    G A  +   G    
Sbjct: 1449 KGEKGHPGLIGLIGPPGEQG---EKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL 1505

Query: 1060 DAVQGIANEDAAQGIANEDAAQGI 1083
               QG      + G A +    G+
Sbjct: 1506 PGPQGPKGNKGSTGPAGQKGDSGL 1529


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score = 98.6 bits (244), Expect = 6e-20
 Identities = 174/919 (18%), Positives = 253/919 (27%), Gaps = 55/919 (5%)

Query: 1116 VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIAN 1175
            ++G + +   QG      + G   +   +G A  D A G+  +    G    D   G+  
Sbjct: 402  LKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPG 461

Query: 1176 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQG 1235
            E   +G      + G   ED   G   E+   G+  E     +  P    GI      +G
Sbjct: 462  EKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRG 521

Query: 1236 IATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDA 1295
            +       G        G   +    G       QG       +G   +  + G+   D 
Sbjct: 522  MDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG 581

Query: 1296 AQG-IAKEDPVQGVANEDPI--QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQG 1352
              G   KE P     N+ P   QG       +GV   D ++G+               +G
Sbjct: 582  PPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH------------KG 629

Query: 1353 IANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVE 1412
               ED       +   +G   E  V G   ED  +G        G      + G   ++ 
Sbjct: 630  EKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLG 689

Query: 1413 VQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIAN 1472
            V G      + G        G        G + E  A+G++ +   +G   E    G   
Sbjct: 690  VPG------LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG---ERGPTGPRG 740

Query: 1473 EDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHG 1532
            +    G   +  A G +  D  H    P   RG+       G        G   +D   G
Sbjct: 741  QRGPRGATGKSGAKGTSGGDGPHG---PPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPG 797

Query: 1533 VANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANED 1592
               +    G   +    G       QG   E    G        G   E  L    A ++
Sbjct: 798  HPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPG-TAGKE 856

Query: 1593 AAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQ--- 1649
              +    P  A G            KD   G+      +G+       G+   +      
Sbjct: 857  GTKGDPGPPGAPG------------KDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPP 904

Query: 1650 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANED 1709
            G A     +G A      G       QG        GV  E    G    D VQG     
Sbjct: 905  GPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPV--- 961

Query: 1710 AVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIA 1769
               G+       GVA ED  +G   +    G       HG        G   +    G  
Sbjct: 962  ---GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGAD 1018

Query: 1770 NEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAH 1829
             E           A G       +    P   +G+      +G   +    G P      
Sbjct: 1019 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1078

Query: 1830 GVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANED 1889
            G A    A G        G       +G   E    G+  E  V+G   E   +G   E 
Sbjct: 1079 GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGE---RGEKGES 1135

Query: 1890 AAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIA 1949
               G       +G   +D  +         G        G   QD A+G   ED   G  
Sbjct: 1136 GQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG-- 1193

Query: 1950 NEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAH 2009
             +  + G   E    G   +    G    +  QG        G        G        
Sbjct: 1194 -QPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPA 1252

Query: 2010 AIAKPDAARGIANEVAAQG 2028
                PD  RG+   V  QG
Sbjct: 1253 GKPGPDGLRGLPGSVGQQG 1271



 Score = 94.7 bits (234), Expect = 9e-19
 Identities = 191/1067 (17%), Positives = 289/1067 (27%), Gaps = 62/1067 (5%)

Query: 923  KEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVH 982
            +E  AQAI +Q A  ++       G        G       +G + ++  QG      + 
Sbjct: 363  QEAQAQAILQQ-ARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLT 421

Query: 983  GVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANED 1042
            G   +   +G A     +G+     ++G    D   G+  E    G        G   ED
Sbjct: 422  GPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED 481

Query: 1043 AAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVA 1102
              +G   E+   G+  E   +G+       GI      +G+      +G        G  
Sbjct: 482  GERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPP 541

Query: 1103 KEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAA- 1161
             +    G       QG       +G   +  + G+   D   G   ++   G        
Sbjct: 542  GQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPS 601

Query: 1162 -----------HGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVA 1210
                        G+   D  +G+      +G   ED   G   +  V G   EV   G  
Sbjct: 602  GPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG---EDGFPGFKGDIGVKGDRGEVGVPGSR 658

Query: 1211 NEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQ 1270
             ED       P+  +G        G        G+  E    GV              + 
Sbjct: 659  GEDG------PEGPKGRTGPTGDPG------PPGLMGEKGKLGV------------PGLP 694

Query: 1271 GIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHED 1330
            G       +G        G + E  A+G++ +    G   E    G   +   +G   + 
Sbjct: 695  GYPGRQGPKGSLGFPGFPGASGEKGARGLSGK---SGPRGERGPTGPRGQRGPRGATGKS 751

Query: 1331 AVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIA 1390
              +G +  D  HG   E   +G+                G   +D + G   +    G  
Sbjct: 752  GAKGTSGGDGPHGPPGE---RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQ 808

Query: 1391 KEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQ 1450
             +    G       QG A E    G        G   E    G A +    G      A 
Sbjct: 809  GKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAP 868

Query: 1451 GIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEV 1510
            G       +G   E  + G A    + G        G A        A      G     
Sbjct: 869  GKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP 928

Query: 1511 ATQGIATEDVADGIANEDAAHGVANEVAAQ---GIANEVAVHGVAIEDAVQGVVKEVTAH 1567
              QG        G+  E    G       Q   G+       GVA ED  +G V +    
Sbjct: 929  GPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQK 988

Query: 1568 GVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQ 1627
            G        G          V    AA A  +P  A G      A          G    
Sbjct: 989  GTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEP-GARGPQGHFGAKGDEGTRGFNGPPGP 1047

Query: 1628 DAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1687
               QG+       G + +    G       +G A  + A G        G        G 
Sbjct: 1048 IGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1107

Query: 1688 AKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAA 1747
              E  + G+  E  V+G   E   +G + +    G       +G   +D   G    V  
Sbjct: 1108 PGESGSPGIQGEPGVKGPRGERGEKGESGQ---PGEPGPPGPKGPTGDDGPKGNPGPVGF 1164

Query: 1748 HGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANE 1807
             G        G   +D  +G   ED       E    G       +    P   RG A  
Sbjct: 1165 PGDPGPPGEGGPRGQDGAKGDRGEDG------EPGQPGSPGPTGENGPPGPLGKRGPAGS 1218

Query: 1808 VAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGV 1867
              ++G      A G P    A G    V   G + +    G+     + G   +    G 
Sbjct: 1219 PGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVG---QQGRPGA 1275

Query: 1868 ANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAV 1927
              +    G      + G+  +  A G        G+      Q    +    G       
Sbjct: 1276 TGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQ 1335

Query: 1928 QGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQG 1974
            +G      A G        G+      +G        G   E   QG
Sbjct: 1336 KGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQG 1382



 Score = 94.7 bits (234), Expect = 9e-19
 Identities = 173/939 (18%), Positives = 255/939 (27%), Gaps = 28/939 (2%)

Query: 62   ADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQG 121
            AD A G+  +  V+G        G+  E    G        G   ED  +G   E+  +G
Sbjct: 435  ADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRG 494

Query: 122  VANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDA 181
            +  E   +G+       G+     V+G+       G        G   +           
Sbjct: 495  LPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPG 554

Query: 182  AQDIANEDAAQGISKEDAVQGIANEDAAQG-IAKEDPVQGVANEDP--VQGVANEDAVQG 238
             Q        +G   +  + G+   D   G   KE P     N+ P   QG       +G
Sbjct: 555  PQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRG 614

Query: 239  VANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDA 298
            V     V G+      +G   ED   G   ++   G   E    G   ED  +G      
Sbjct: 615  VKG---VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTG 671

Query: 299  VQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIAN 358
              G      + G   ++   G+                G       +G        G   
Sbjct: 672  PTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG 731

Query: 359  EDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAH 418
            E    G   +    G   +   +G    D  HG        + +  P   +G        
Sbjct: 732  ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHG----PPGERGLPGPQGPNGFPGPKGPP 787

Query: 419  GIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANED 478
            G   +D   G   +    G   +    G       QG A E    G        G   E 
Sbjct: 788  GPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQ 847

Query: 479  AVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVA 538
             + G A +    G      A     P   RG   E    G A      G        G A
Sbjct: 848  GLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPA 907

Query: 539  NEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVH 598
                  G A               G       +G+  E    G    D   GV   V + 
Sbjct: 908  GSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRD---GVQGPVGLP 964

Query: 599  GVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANE 658
            G A      GVA ED   G   +   +G       HG        G V +    G    E
Sbjct: 965  GPA---GPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAG-ADGE 1020

Query: 659  DAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGI 718
              A+       A G       +G       QG+      +G   +V   G       +G 
Sbjct: 1021 PGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGP 1080

Query: 719  ANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEV 778
            A  + A G        G        G   E  + G+  E  V+G   E   +G   E   
Sbjct: 1081 AGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGE---RGEKGESGQ 1137

Query: 779  QGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANE 838
             G       +G   +D   G    V   G        G   +D A+G   ED   G   +
Sbjct: 1138 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGED---GEPGQ 1194

Query: 839  DAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANE 898
              + G   E    G   +    G    E   G    +    AI  P     +   G A +
Sbjct: 1195 PGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1254

Query: 899  VAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVA 958
                G+    +   + +    G T +              +  +  A+G        G+ 
Sbjct: 1255 PGPDGL--RGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLI 1312

Query: 959  NEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEV 997
                 QG   E   +G+       G   E  + G +  +
Sbjct: 1313 GPPGEQG---EKGDRGLPGPQGSPGQKGEMGIPGASGPI 1348



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 195/1042 (18%), Positives = 294/1042 (28%), Gaps = 72/1042 (6%)

Query: 392  VVANEDAAQAIAK--------PDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDA 443
            V A E  AQAI +        P    G        G       +G + ++   G      
Sbjct: 360  VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQG 419

Query: 444  VQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAK 503
            + G   +   +G A  D A+G+  +  V+G    D + G+  E    G            
Sbjct: 420  LTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 479

Query: 504  PDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHG 563
             D  RG   E+  +G+  E    G+       G+       G+           P    G
Sbjct: 480  EDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPG 539

Query: 564  IANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANE-- 621
               +  T G        G        G   +  + G+   D   G   ++   G      
Sbjct: 540  PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQG 599

Query: 622  -DAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAH 680
                QG        GV   D ++G+       G    ED            G   EV   
Sbjct: 600  PSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG----EDGFPGFKGDIGVKGDRGEVGVP 655

Query: 681  GIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANED 740
            G   ED  +G        G        G   +  V G+      QG       +G     
Sbjct: 656  GSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQG------PKGSLGFP 709

Query: 741  AVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIA 800
               G + E  A G++ +    G   E    G   +   +G   +   +G +  D  HG  
Sbjct: 710  GFPGASGEKGARGLSGK---SGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPP 766

Query: 801  NEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQ 860
             E    G+       G        G   +D + G        G   EV   G T      
Sbjct: 767  GE---RGLPGPQGPNGFPGPKGPPGPPGKDGLPG------HPGQRGEVGFQGKTGPPGPP 817

Query: 861  GVVNEEALHGVVA--NEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAA 918
            GVV  +   G      E        P    G+   G A +   +G      A G  KD  
Sbjct: 818  GVVGPQGAAGETGPMGERGHPGPPGPPGEQGL--PGTAGKEGTKGDPGPPGAPG--KDGP 873

Query: 919  HGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANE 978
             G+      + +        +   +   G      + G   E  A G    +   G    
Sbjct: 874  AGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPG---ERGAAGSGGPIGPPGRPGP 930

Query: 979  DAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGI 1038
                G A E  V G    +   G   +D +QG        G+       G+A ED  +G 
Sbjct: 931  QGPPGAAGEKGVPGEKGPI---GPTGRDGVQGPV------GLPGPAGPPGVAGEDGDKGE 981

Query: 1039 ANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAV 1098
              +   +G       HG        G   +  A G   E  A+G       +G   ++  
Sbjct: 982  VGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKG---DEGT 1038

Query: 1099 HGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANE 1158
             G       +G      +QG+      +G   +V   G       +G A  + A G    
Sbjct: 1039 RGF------NGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGP 1092

Query: 1159 VAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAI 1218
                G       +G   E  + GI  E  V+G   E    G   E    G          
Sbjct: 1093 PGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGE---RGEKGESGQPGEPGPPGPKGP 1149

Query: 1219 AKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAA 1278
               D  +G    V   G        G   +D A G   E    G   +    G   E+  
Sbjct: 1150 TGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG---QPGSPGPTGENGP 1206

Query: 1279 QGIAKEDAVQGIANEDAAQG--IAKEDP-VQGVANEDPIQGVANEVEVQGVAHEDAVQGI 1335
             G   +    G    +  QG   AK DP   G   +    G A      G      + G 
Sbjct: 1207 PGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGS 1266

Query: 1336 ANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPV 1395
              +    G   +    G         +  +  A+G      + G+      QG   E   
Sbjct: 1267 VGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQG---EKGD 1323

Query: 1396 QGVANEDAVQGVANEVEVQGVA 1417
            +G+       G   E+ + G +
Sbjct: 1324 RGLPGPQGSPGQKGEMGIPGAS 1345



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 190/1017 (18%), Positives = 273/1017 (26%), Gaps = 73/1017 (7%)

Query: 916  DAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGV 975
            D A G+  +   +     D    +  E   +G        G   ED  +G   E+  +G+
Sbjct: 436  DGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGL 495

Query: 976  ANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAA 1035
              E    G+       G+     V+G+      +G        G   +    G       
Sbjct: 496  PGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGP 555

Query: 1036 QGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANE 1095
            QG       +G   +    G+   D   G   ++   G        G        G    
Sbjct: 556  QGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGV 615

Query: 1096 DAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGI 1155
              V G+       G   ED   G   +  V+G   EV V G   ED  +G        G 
Sbjct: 616  KGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEG---PKGRTGP 672

Query: 1156 ANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAA 1215
              +    G+  E    G+       G       +G        G + E  A G++ +   
Sbjct: 673  TGDPGPPGLMGEKGKLGV---PGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGP 729

Query: 1216 HAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANE 1275
                 P   RG   +   +G   +  A G +  D  HG   E    G+       G    
Sbjct: 730  RGERGPTGPRG---QRGPRGATGKSGAKGTSGGDGPHGPPGE---RGLPGPQGPNGFPGP 783

Query: 1276 DAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGI 1335
                G   +D + G   +    G   +    G       QG A E    G        G 
Sbjct: 784  KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGP 843

Query: 1336 ANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPV 1395
              E    G A ++  +G      A         +G   E  + G A     +G       
Sbjct: 844  PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP 903

Query: 1396 QGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANE 1455
             G A     +G A      G       QG        G+  E    G    D  QG    
Sbjct: 904  PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQG---- 959

Query: 1456 DAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGI 1515
                G+       G+A ED   G   +    G       H    P    G   +    G 
Sbjct: 960  --PVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAG- 1016

Query: 1516 ATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAV 1575
                 ADG   E  A G      A+G       +G      +QG+       G + E   
Sbjct: 1017 -----ADG---EPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGL------PGPSGEKGE 1062

Query: 1576 QGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIAN 1635
             G V                    P    G A    A          G       +G   
Sbjct: 1063 TGDV-------------GPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG 1109

Query: 1636 EVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHG 1695
            E  + GI  E  V+G   E   +G   E    G       +G   +D   G    V   G
Sbjct: 1110 ESGSPGIQGEPGVKGPRGERGEKG---ESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPG 1166

Query: 1696 VANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDA 1755
                    G   +D  +G       +G   E    G       +G    +   G A    
Sbjct: 1167 DPGPPGEGGPRGQDGAKG------DRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPG 1220

Query: 1756 AQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIAT 1815
            ++G       +G             V   G A +        PD  RG+   V  QG   
Sbjct: 1221 SEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPG------PDGLRGLPGSVGQQGRPG 1274

Query: 1816 EDVADGIP---NEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVE 1872
                 G P         G+  +  A G      + G+      QG   +  + G      
Sbjct: 1275 ATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPG------ 1328

Query: 1873 VQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQG 1929
             QG   +    GI       G        G A    A+        +G   E  VQG
Sbjct: 1329 PQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKG---EKGVQG 1382



 Score = 88.6 bits (218), Expect = 7e-17
 Identities = 172/896 (19%), Positives = 247/896 (27%), Gaps = 79/896 (8%)

Query: 654  VVANEDAAQAIAK--------PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVA 705
            V A E  AQAI +        P    G        G       +G + +   QG      
Sbjct: 360  VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQG 419

Query: 706  AHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVAN 765
              G   +   +G A  D A+G+  +  V+G    D + G+  E    G      + G   
Sbjct: 420  LTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 479

Query: 766  EDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQG 825
            ED  +G   E+  +G+  E   +G+       GI       GV   D  QG       QG
Sbjct: 480  EDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIP---GPPGVRGMDGPQGPKGSLGPQG 536

Query: 826  VANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPD 885
                    G        G    +  HG   E   QG   +  L G+  ++       K  
Sbjct: 537  EPGPPGQQGTPGTQGLPGPQGAIGPHG---EKGPQG---KPGLPGMPGSDGPPGHPGKEG 590

Query: 886  AAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAA 945
                  N+G +      G        G+                                
Sbjct: 591  PPGTKGNQGPSGPQGPLGYPGPRGVKGV-------------------------------- 618

Query: 946  QGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHK 1005
             G+       G   ED   G   ++  +G   E  V G   ED  +G        G    
Sbjct: 619  DGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGP 678

Query: 1006 DAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGI 1065
              + G   +    G+       G       +G        G + E  A G+S +   +G 
Sbjct: 679  PGLMGEKGKLGVPGLP------GYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG- 731

Query: 1066 ANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAV 1125
              E    G   +   +G   +   +G +  D  HG   E            +G+      
Sbjct: 732  --ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGE------------RGLPGPQGP 777

Query: 1126 QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHE 1185
             G        G   +D + G   +    G   +    G       QG A E    G    
Sbjct: 778  NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 837

Query: 1186 DAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGI 1245
                G   E  + G A +    G      A     P   RG   E    G A      G 
Sbjct: 838  PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 897

Query: 1246 ANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPV 1305
                   G A      G +      G       QG       +G+  E    G    D V
Sbjct: 898  EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGV 957

Query: 1306 QG-VANEDPI--QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDI 1362
            QG V    P    GVA E   +G   +   +G       HG        G   +  A   
Sbjct: 958  QGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGA 1017

Query: 1363 ANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAV 1422
              E  A+G       +G        G      +QG+      +G   +V   G       
Sbjct: 1018 DGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGP 1077

Query: 1423 QGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE 1482
            +G A  + A G        G       +G   E  + GI  E  V+G   E    G + +
Sbjct: 1078 RGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQ 1137

Query: 1483 ------VAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHG 1532
                      G   +D       P    G        G   +D A G   ED   G
Sbjct: 1138 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG 1193



 Score = 87.4 bits (215), Expect = 1e-16
 Identities = 177/965 (18%), Positives = 263/965 (27%), Gaps = 65/965 (6%)

Query: 1306 QGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANE 1365
            +G A  D  +G+  +  V+G    D + G+  E    G        G   ED  +    E
Sbjct: 430  RGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGE 489

Query: 1366 DAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGI 1425
               +G+  E   +G+       GI     V+G+   D  QG    +  QG       QG 
Sbjct: 490  IGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGM---DGPQGPKGSLGPQGEPGPPGQQGT 546

Query: 1426 ANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAA 1485
                   G    +  HG        G+     + G       +G        G +     
Sbjct: 547  PGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPS---GP 603

Query: 1486 HGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANE 1545
             G         +   D  RG+      +G            ED   G   ++  +G   E
Sbjct: 604  QGPLGYPGPRGVKGVDGIRGLKGHKGEKG------------EDGFPGFKGDIGVKGDRGE 651

Query: 1546 VAVHGVAIEDAVQGVVKEVTAHGVANEDAV---QGVVNEDALHSVVANEDAAQAIAKPDA 1602
            V V G   ED  +G        G      +   +G +    L      +    ++  P  
Sbjct: 652  VGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGF 711

Query: 1603 AHGIANEVAAHSIANKDAAQGIAN------QDAAQGIANEVAAHGISKEDAVQGIANEDA 1656
              G + E  A  ++ K   +G         Q   +G   +  A G S  D   G   E  
Sbjct: 712  P-GASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGE-- 768

Query: 1657 AQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVAN 1716
             +G+       G        G   +D + G        G   E   QG        GV  
Sbjct: 769  -RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHP------GQRGEVGFQGKTGPPGPPGV-- 819

Query: 1717 EVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHS 1776
             V  QG A E    G        G   E    G A ++  +G        G      +  
Sbjct: 820  -VGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRG 878

Query: 1777 VAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVA 1836
               E    G A          P    G A     +G A      G P      G      
Sbjct: 879  FPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAG 938

Query: 1837 AHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIAN 1896
              G+  E    G    D  QG     P+ G+       GVA ED  +G   +    G   
Sbjct: 939  EKGVPGEKGPIGPTGRDGVQG-----PV-GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKG 992

Query: 1897 EDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQG 1956
                 G            +  A G   E   +G      A+G   ++  +G        G
Sbjct: 993  NKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKG---DEGTRGF------NG 1043

Query: 1957 IANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDA 2016
                +   G+      +G   +    G       +G A  +   G            P  
Sbjct: 1044 PPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPG 1103

Query: 2017 ARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVA 2076
             +G   E  + GI  E    G   E    G + +        P    G  ++G       
Sbjct: 1104 EKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTG--DDGPKGNPGP 1161

Query: 2077 DGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEV 2136
             G   D   G   E   +    QD A G   ED   G        G        G     
Sbjct: 1162 VGFPGDP--GPPGEGGPRG---QDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPA 1216

Query: 2137 AAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVA 2196
             + G       +G   +  A G   +    G A      G      + G   +    G  
Sbjct: 1217 GSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGAT 1276

Query: 2197 NEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQ 2256
             +    G        G+  +  A+G   E    G+   +   G   E   R +     + 
Sbjct: 1277 GQAGPPGPVGPPGLPGLRGDAGAKG---EKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSP 1333

Query: 2257 GIANE 2261
            G   E
Sbjct: 1334 GQKGE 1338



 Score = 85.5 bits (210), Expect = 6e-16
 Identities = 215/1201 (17%), Positives = 326/1201 (27%), Gaps = 76/1201 (6%)

Query: 16   SSEESLVHKDRGDGERPVNVRVVQVAPLRHESTPYEDT--VHDIANED--ADAAHGITNE 71
            S E+  +  + G  ERP N +     P R + +P +    +H   N++  + AAHG    
Sbjct: 220  SCEQKELECEGGQRERPQNQQ-----PHRAQRSPQQQPSRLHRPQNQEPQSQAAHG---- 270

Query: 72   DAVQGVANEVAAQGVANEDA-AHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQG 130
               +G+  E     V        G        G+      QG    V   G        G
Sbjct: 271  --PRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAG 328

Query: 131  VANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDA 190
            +   D   G      +          G    D    +A ++A      + A   +     
Sbjct: 329  LPGSDGAPGPPGTSLMLPFR-----FGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPG 383

Query: 191  AQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAH 250
              G +      G       +G + +   QG      + G   +   +G A     +G+  
Sbjct: 384  PMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPG 443

Query: 251  EDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHG 310
            +  V+G    D   G+  E    G        G   ED  +G   E   +G+  E    G
Sbjct: 444  DPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRG 503

Query: 311  VAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKEVT 370
            +       G+        +   D   G    +  QG        G        G    + 
Sbjct: 504  LLGPKGPPGIPGPPGVRGM---DGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIG 560

Query: 371  AHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIA 430
             HG   E   QG   +  L G+  ++        P    G        G       QG  
Sbjct: 561  PHG---EKGPQG---KPGLPGMPGSDG-------PPGHPGKEGPPGTKGNQGPSGPQGPL 607

Query: 431  NEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAH 490
                  G+   D ++G+      +G   ED   G   +  V+G   E  V G   E    
Sbjct: 608  GYPGPRGVKGVDGIRGLKGHKGEKG---EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPE 664

Query: 491  GVANKDAAHAIAKPDAARGIANEVAAQGI---ATEDVADGIANEDAVHGVANEVAAHGVA 547
            G   +        P    G   ++   G+          G        G + E  A G++
Sbjct: 665  GPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLS 724

Query: 548  NEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQ 607
             +        P    G   +   +G   +  A G +  D  HG   E  + G    +   
Sbjct: 725  GKSGPRGERGPTGPRG---QRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 781

Query: 608  GVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKP 667
            G        G        G   EV   G        GVV         A E         
Sbjct: 782  GPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQG----AAGETGPMGERGH 837

Query: 668  DAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGI 727
                G   E    G A ++  +G      A G        G   E  + G A     +G 
Sbjct: 838  PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 897

Query: 728  AHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAV 787
                   G A      G A      G       QG       +GV  E    G    D V
Sbjct: 898  EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGV 957

Query: 788  QGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKE 847
            QG        G+       GVA ED  +G   +   +G       HG        G   +
Sbjct: 958  QGPV------GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQ 1011

Query: 848  VTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATE 907
              A G   E   +G       H     ++  +    P    G+  +G+      +G  T 
Sbjct: 1012 PGAAGADGEPGARGPQG----HFGAKGDEGTRGFNGPPGPIGL--QGLPGPSGEKG-ETG 1064

Query: 908  DVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVA 967
            DV          G       +  A  + A          G        G   E  + G+ 
Sbjct: 1065 DV-------GPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQ 1117

Query: 968  NEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAH 1027
             E   +G   E    G   E    G       +G    D  +G        G        
Sbjct: 1118 GEPGVKGPRGE---RGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEG 1174

Query: 1028 GIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHED 1087
            G   +D A+G   ED   G        G +      G      + G       +G   + 
Sbjct: 1175 GPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDP 1234

Query: 1088 AVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIA 1147
               G   +    G A      G      + G   +    G   +    G      + G+ 
Sbjct: 1235 GAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLR 1294

Query: 1148 NEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAH 1207
             +  A G        G+      QG   E   +G+       G   E  + G +  +   
Sbjct: 1295 GDAGAKGEKGHPGLIGLIGPPGEQG---EKGDRGLPGPQGSPGQKGEMGIPGASGPIGPG 1351

Query: 1208 G 1208
            G
Sbjct: 1352 G 1352



 Score = 85.5 bits (210), Expect = 6e-16
 Identities = 192/1049 (18%), Positives = 293/1049 (27%), Gaps = 76/1049 (7%)

Query: 67   GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126
            G T      G       +G + +    G        G   +   +G A    A+G+  + 
Sbjct: 386  GYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDP 445

Query: 127  AVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIA 186
             V+G    D + G+  E   +G        G   ED  +G   E   + +  E   + + 
Sbjct: 446  GVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLL 505

Query: 187  NEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQ 246
                  GI     V+G+      +G        G   +    G       QG       +
Sbjct: 506  GPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEK 565

Query: 247  GVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 306
            G   +  + G+   D   G   +    G        G       QG       +G+   D
Sbjct: 566  GPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSG------PQGPLGYPGPRGVKGVD 619

Query: 307  AVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVA 366
             + G+       G   ED            G   EV   G   ED  +G        G  
Sbjct: 620  GIRGLK---GHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTG-- 674

Query: 367  KEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAA 426
             +    G+  E    GV     L G    +    ++  P    G + E  A G++ +   
Sbjct: 675  -DPGPPGLMGEKGKLGV---PGLPGYPGRQGPKGSLGFP-GFPGASGEKGARGLSGKSGP 729

Query: 427  QGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKE 486
            +G        G   +   +G   +  A+G +  D   G   E   +G+      +G    
Sbjct: 730  RGERGPTGPRG---QRGPRGATGKSGAKGTSGGDGPHGPPGE---RGLPGPQGPNGFPGP 783

Query: 487  VAAHGVANKDA--AHAIAKPDAA-------RGIANEVAAQGIATEDVADGIANEDAVHGV 537
                G   KD    H   + +          G    V  QG A E    G        G 
Sbjct: 784  KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGP 843

Query: 538  ANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAV 597
              E    G A ++       P  A G       +G   E    G A      G       
Sbjct: 844  PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP 903

Query: 598  HGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVAN 657
             G A     +G A      G       QG        GV  E    G    D + G V  
Sbjct: 904  PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPV-- 961

Query: 658  EDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQG 717
                          G+       G+A ED  +G   +   +G       HG        G
Sbjct: 962  --------------GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIG 1007

Query: 718  IANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVE 777
               +  A G   E   +G        G       +G      +QG+      +G   +V 
Sbjct: 1008 PVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVG 1067

Query: 778  VQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVAN 837
              G       +G A  + A G        G       +G   E  + G+  E  V G   
Sbjct: 1068 PMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRG 1127

Query: 838  EDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVAN 897
            E   +G +      G   E    G        G   N      +  P         G   
Sbjct: 1128 ERGEKGES------GQPGEPGPPGPKGPTGDDGPKGNPG---PVGFPGDPGPPGEGGPRG 1178

Query: 898  EVAAQGIATEDVADGIAKDAAHGITKEEAAQA-IAKQDAAHSITNE--DAAQGVANEDAA 954
            +  A+G   ED   G  +  + G T E      + K+  A S  +E     +G   +  A
Sbjct: 1179 QDGAKGDRGEDGEPG--QPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGA 1236

Query: 955  HGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANE 1014
             G   +    G A      G      + G   +    G   +    G      + G+  +
Sbjct: 1237 IGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGD 1296

Query: 1015 DAAH------GIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGIS------KEDAV 1062
              A       G+   +   G   E   +G+     + G   E+   G S          +
Sbjct: 1297 AGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGL 1356

Query: 1063 QGIANEDAAQGIANEDAAQGIAHEDAVQG 1091
             G A    A+G       +G   E  VQG
Sbjct: 1357 PGPAGPKGAKGATGPGGPKG---EKGVQG 1382



 Score = 75.5 bits (184), Expect = 6e-13
 Identities = 153/878 (17%), Positives = 231/878 (26%), Gaps = 40/878 (4%)

Query: 1413 VQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQ---- 1468
            V+G    +   G+       G    V   G        G+   D A G      +     
Sbjct: 290  VEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRF 349

Query: 1469 GIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANED 1528
            G    D    VA + A      + A  A+  P    G        G        G + + 
Sbjct: 350  GSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDL 409

Query: 1529 AAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVV 1588
               G        G   +    G A  D  +G+  +    G    D + G+  E       
Sbjct: 410  GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRG-- 467

Query: 1589 ANEDAAQAIAKP---DAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKE 1645
              +  AQ +  P   D   G   E+    +  +   +G+       GI       G+   
Sbjct: 468  --DTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGP 525

Query: 1646 DAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGV 1705
               +G        G   +    G       QG        G   +    G+   D   G 
Sbjct: 526  QGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH 585

Query: 1706 ANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAV 1765
              ++   G        G        G        GI       G   ED   G   +  V
Sbjct: 586  PGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGV 645

Query: 1766 QGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNE 1825
            +G   E  V     E    G            P    G   ++   G+       G P  
Sbjct: 646  KGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLP------GYPGR 699

Query: 1826 DAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGI 1885
                G        G S E   +G++ +   +G   E    G   +   +G   +   +G 
Sbjct: 700  QGPKGSLGFPGFPGASGEKGARGLSGKSGPRG---ERGPTGPRGQRGPRGATGKSGAKGT 756

Query: 1886 ANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAV 1945
            +  D  HG   E   +G+                G   +D + G   Q    G   +   
Sbjct: 757  SGGDGPHGPPGE---RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGP 813

Query: 1946 QGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANE 2005
             G       QG A E    G        G   E    G A ++  +G   +    G   +
Sbjct: 814  PGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKG---DPGPPGAPGK 870

Query: 2006 DAAHAIAKPDAARGIANEVAAQGIATEDVADG------IANEDAAHGVANEDAAQAIAKP 2059
            D    +      RG+       G+   +   G         E  A G            P
Sbjct: 871  DGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGP 930

Query: 2060 DAAHGIANE-GIATEDVADG-IAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNE 2117
                G A E G+  E    G    D VQG         +       G+  ED  +G   +
Sbjct: 931  QGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVG------LPGPAGPPGVAGEDGDKGEVGD 984

Query: 2118 VAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGI 2177
               +G       HG        G   +  A G   E  A+G       +G        G 
Sbjct: 985  PGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGP 1044

Query: 2178 AHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAV 2237
                 +QG+      +G   +V   G       +G A    A G        G       
Sbjct: 1045 PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGE 1104

Query: 2238 HGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVHG 2275
             G   E  +  +  E   +G   E    G + +    G
Sbjct: 1105 KGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPG 1142



 Score = 75.5 bits (184), Expect = 6e-13
 Identities = 165/933 (17%), Positives = 241/933 (25%), Gaps = 98/933 (10%)

Query: 1343 GIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANED 1402
            G    D    +A ++A      + A   +       G        G      ++G + + 
Sbjct: 350  GSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDL 409

Query: 1403 AVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIA 1462
              QG      + G   +   +G A  D A G+  +    G    D   G+  E   +G  
Sbjct: 410  GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDT 469

Query: 1463 HEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHA---------IAKPDAARGIANEVATQ 1513
                + G   ED   G   E+   G+  E              I  P   RG+      +
Sbjct: 470  GAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPK 529

Query: 1514 GIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANED 1573
            G      + G   E    G       QG+       G   E   QG   +    G+   D
Sbjct: 530  G------SLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQG---KPGLPGMPGSD 580

Query: 1574 AVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGI 1633
               G   ++       N+        P    G         +   D  +G+      +G 
Sbjct: 581  GPPGHPGKEGPPGTKGNQG-------PSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG- 632

Query: 1634 ANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAA 1693
                                ED   G   +   +G   E  V G   ED   G       
Sbjct: 633  --------------------EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGP 672

Query: 1694 HGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANE 1753
             G      + G   +  V G      + G       +G        G + E  A G++ +
Sbjct: 673  TGDPGPPGLMGEKGKLGVPG------LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGK 726

Query: 1754 DAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGI 1813
               +G   E    G   +        +  A G +  D  H    P   RG+       G 
Sbjct: 727  SGPRG---ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHG---PPGERGLPGPQGPNGF 780

Query: 1814 ATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEV 1873
                   G P +D   G        G   E   QG        G+      QG A E   
Sbjct: 781  PGPKGPPGPPGKDGLPG------HPGQRGEVGFQGKTGPPGPPGVVGP---QGAAGETGP 831

Query: 1874 QGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQ 1933
             G        G   E    G A ++  +G      A         +G   E  + G A  
Sbjct: 832  MGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGG 891

Query: 1934 DAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGI 1993
               +G        G A     +G A      G       QG       +G+  E    G 
Sbjct: 892  PGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP 951

Query: 1994 ANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAA 2053
               D V G                 G+       G+A ED   G   +    G       
Sbjct: 952  TGRDGVQGPV---------------GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGE 996

Query: 2054 QAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQG 2113
                 P    G              + +    G   E  A+       A G        G
Sbjct: 997  HGPPGPPGPIG-------------PVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNG 1043

Query: 2114 VTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVE 2173
                +  QG+       G   +V   G       +G A    A G        G      
Sbjct: 1044 PPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPG 1103

Query: 2174 VQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVAN 2233
             +G   +    GI  E   +G   E    G   E    G       +G   +D  +G   
Sbjct: 1104 EKGEPGESGSPGIQGEPGVKGPRGE---RGEKGESGQPGEPGPPGPKGPTGDDGPKGNPG 1160

Query: 2234 EVAVHGVANEDAARHMAKEDAAQGIANEDAAHG 2266
             V   G            +D A+G   ED   G
Sbjct: 1161 PVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG 1193



 Score = 56.6 bits (135), Expect = 3e-07
 Identities = 85/483 (17%), Positives = 132/483 (27%), Gaps = 13/483 (2%)

Query: 1798 PDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQG 1857
            P    G   +   +G A  D A G+P +    G        G+  E   +G        G
Sbjct: 417  PQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPG 476

Query: 1858 IAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAN--- 1914
               ED  +G   E+  +G+  E   +G+       GI      +G+      +       
Sbjct: 477  PPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQG 536

Query: 1915 EDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQG 1974
            E    G       QG+     A G   E   QG        G        G       +G
Sbjct: 537  EPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKG 596

Query: 1975 IANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDV 2034
                   QG       +G+   D + G+            D   G   ++  +G   E  
Sbjct: 597  NQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG---EDGFPGFKGDIGVKGDRGEVG 653

Query: 2035 ADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQ 2094
              G   ED   G            P    G   + +    +         +G        
Sbjct: 654  VPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK-LGVPGLPGYPGRQGPKGSLGFPGFP 712

Query: 2095 AIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEV 2154
              + +  A G++ +   +G   E    G   +    G   +  A G +  D   G   E 
Sbjct: 713  GASGEKGARGLSGKSGPRG---ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGE- 768

Query: 2155 AAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVA 2214
              +G+       G        G   KD + G   +    G   +    G       QG A
Sbjct: 769  --RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAA 826

Query: 2215 NEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVH 2274
             E    G        G   E  + G A ++  +       A G        G   E  + 
Sbjct: 827  GETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLP 886

Query: 2275 GIA 2277
            G A
Sbjct: 887  GTA 889



 Score = 37.7 bits (86), Expect = 0.14
 Identities = 73/380 (19%), Positives = 103/380 (27%), Gaps = 34/380 (8%)

Query: 1927 VQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQ---- 1982
            V+G    +   G+     +QG        G        G+   D A G            
Sbjct: 290  VEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRF 349

Query: 1983 GIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANED 2042
            G    D    +A ++A      + A  A+  P    G        G   +  + G+  E 
Sbjct: 350  GSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLG---QPGSPGLKGES 406

Query: 2043 AAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAED----------AVQGITNEEA 2092
               G       Q +  P    G    G A  D A G+  D           + G+  E+ 
Sbjct: 407  GDLGPQGPRGPQGLTGPPGKAG--RRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKG 464

Query: 2093 AQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANE------DA 2146
             +         G   ED  +G   E+  +G+  E    G+       G+         D 
Sbjct: 465  HRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDG 524

Query: 2147 AQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVAN 2206
             QG    +  QG       QG       QG+       G   E   QG        G   
Sbjct: 525  PQGPKGSLGPQGEPGPPGQQGTPG---TQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG 581

Query: 2207 EDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAK------EDAAQGIAN 2260
                 G       +G       QG        GV   D  R +        ED   G   
Sbjct: 582  PPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKG 641

Query: 2261 EDAAHGIANEDAVHGIANED 2280
            +    G   E  V G   ED
Sbjct: 642  DIGVKGDRGEVGVPGSRGED 661


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score = 98.6 bits (244), Expect = 6e-20
 Identities = 174/919 (18%), Positives = 253/919 (27%), Gaps = 55/919 (5%)

Query: 1116 VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIAN 1175
            ++G + +   QG      + G   +   +G A  D A G+  +    G    D   G+  
Sbjct: 509  LKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPG 568

Query: 1176 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQG 1235
            E   +G      + G   ED   G   E+   G+  E     +  P    GI      +G
Sbjct: 569  EKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRG 628

Query: 1236 IATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDA 1295
            +       G        G   +    G       QG       +G   +  + G+   D 
Sbjct: 629  MDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG 688

Query: 1296 AQG-IAKEDPVQGVANEDPI--QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQG 1352
              G   KE P     N+ P   QG       +GV   D ++G+               +G
Sbjct: 689  PPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH------------KG 736

Query: 1353 IANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVE 1412
               ED       +   +G   E  V G   ED  +G        G      + G   ++ 
Sbjct: 737  EKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLG 796

Query: 1413 VQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIAN 1472
            V G      + G        G        G + E  A+G++ +   +G   E    G   
Sbjct: 797  VPG------LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG---ERGPTGPRG 847

Query: 1473 EDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHG 1532
            +    G   +  A G +  D  H    P   RG+       G        G   +D   G
Sbjct: 848  QRGPRGATGKSGAKGTSGGDGPHG---PPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPG 904

Query: 1533 VANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANED 1592
               +    G   +    G       QG   E    G        G   E  L    A ++
Sbjct: 905  HPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPG-TAGKE 963

Query: 1593 AAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQ--- 1649
              +    P  A G            KD   G+      +G+       G+   +      
Sbjct: 964  GTKGDPGPPGAPG------------KDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPP 1011

Query: 1650 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANED 1709
            G A     +G A      G       QG        GV  E    G    D VQG     
Sbjct: 1012 GPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPV--- 1068

Query: 1710 AVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIA 1769
               G+       GVA ED  +G   +    G       HG        G   +    G  
Sbjct: 1069 ---GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGAD 1125

Query: 1770 NEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAH 1829
             E           A G       +    P   +G+      +G   +    G P      
Sbjct: 1126 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1185

Query: 1830 GVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANED 1889
            G A    A G        G       +G   E    G+  E  V+G   E   +G   E 
Sbjct: 1186 GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGE---RGEKGES 1242

Query: 1890 AAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIA 1949
               G       +G   +D  +         G        G   QD A+G   ED   G  
Sbjct: 1243 GQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG-- 1300

Query: 1950 NEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAH 2009
             +  + G   E    G   +    G    +  QG        G        G        
Sbjct: 1301 -QPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPA 1359

Query: 2010 AIAKPDAARGIANEVAAQG 2028
                PD  RG+   V  QG
Sbjct: 1360 GKPGPDGLRGLPGSVGQQG 1378



 Score = 94.7 bits (234), Expect = 9e-19
 Identities = 191/1067 (17%), Positives = 289/1067 (27%), Gaps = 62/1067 (5%)

Query: 923  KEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVH 982
            +E  AQAI +Q A  ++       G        G       +G + ++  QG      + 
Sbjct: 470  QEAQAQAILQQ-ARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLT 528

Query: 983  GVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANED 1042
            G   +   +G A     +G+     ++G    D   G+  E    G        G   ED
Sbjct: 529  GPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED 588

Query: 1043 AAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVA 1102
              +G   E+   G+  E   +G+       GI      +G+      +G        G  
Sbjct: 589  GERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPP 648

Query: 1103 KEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAA- 1161
             +    G       QG       +G   +  + G+   D   G   ++   G        
Sbjct: 649  GQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPS 708

Query: 1162 -----------HGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVA 1210
                        G+   D  +G+      +G   ED   G   +  V G   EV   G  
Sbjct: 709  GPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG---EDGFPGFKGDIGVKGDRGEVGVPGSR 765

Query: 1211 NEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQ 1270
             ED       P+  +G        G        G+  E    GV              + 
Sbjct: 766  GEDG------PEGPKGRTGPTGDPG------PPGLMGEKGKLGV------------PGLP 801

Query: 1271 GIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHED 1330
            G       +G        G + E  A+G++ +    G   E    G   +   +G   + 
Sbjct: 802  GYPGRQGPKGSLGFPGFPGASGEKGARGLSGK---SGPRGERGPTGPRGQRGPRGATGKS 858

Query: 1331 AVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIA 1390
              +G +  D  HG   E   +G+                G   +D + G   +    G  
Sbjct: 859  GAKGTSGGDGPHGPPGE---RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQ 915

Query: 1391 KEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQ 1450
             +    G       QG A E    G        G   E    G A +    G      A 
Sbjct: 916  GKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAP 975

Query: 1451 GIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEV 1510
            G       +G   E  + G A    + G        G A        A      G     
Sbjct: 976  GKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP 1035

Query: 1511 ATQGIATEDVADGIANEDAAHGVANEVAAQ---GIANEVAVHGVAIEDAVQGVVKEVTAH 1567
              QG        G+  E    G       Q   G+       GVA ED  +G V +    
Sbjct: 1036 GPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQK 1095

Query: 1568 GVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQ 1627
            G        G          V    AA A  +P  A G      A          G    
Sbjct: 1096 GTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEP-GARGPQGHFGAKGDEGTRGFNGPPGP 1154

Query: 1628 DAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1687
               QG+       G + +    G       +G A  + A G        G        G 
Sbjct: 1155 IGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1214

Query: 1688 AKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAA 1747
              E  + G+  E  V+G   E   +G + +    G       +G   +D   G    V  
Sbjct: 1215 PGESGSPGIQGEPGVKGPRGERGEKGESGQ---PGEPGPPGPKGPTGDDGPKGNPGPVGF 1271

Query: 1748 HGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANE 1807
             G        G   +D  +G   ED       E    G       +    P   RG A  
Sbjct: 1272 PGDPGPPGEGGPRGQDGAKGDRGEDG------EPGQPGSPGPTGENGPPGPLGKRGPAGS 1325

Query: 1808 VAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGV 1867
              ++G      A G P    A G    V   G + +    G+     + G   +    G 
Sbjct: 1326 PGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVG---QQGRPGA 1382

Query: 1868 ANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAV 1927
              +    G      + G+  +  A G        G+      Q    +    G       
Sbjct: 1383 TGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQ 1442

Query: 1928 QGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQG 1974
            +G      A G        G+      +G        G   E   QG
Sbjct: 1443 KGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQG 1489



 Score = 94.7 bits (234), Expect = 9e-19
 Identities = 173/939 (18%), Positives = 255/939 (27%), Gaps = 28/939 (2%)

Query: 62   ADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQG 121
            AD A G+  +  V+G        G+  E    G        G   ED  +G   E+  +G
Sbjct: 542  ADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRG 601

Query: 122  VANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDA 181
            +  E   +G+       G+     V+G+       G        G   +           
Sbjct: 602  LPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPG 661

Query: 182  AQDIANEDAAQGISKEDAVQGIANEDAAQG-IAKEDPVQGVANEDP--VQGVANEDAVQG 238
             Q        +G   +  + G+   D   G   KE P     N+ P   QG       +G
Sbjct: 662  PQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRG 721

Query: 239  VANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDA 298
            V     V G+      +G   ED   G   ++   G   E    G   ED  +G      
Sbjct: 722  VKG---VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTG 778

Query: 299  VQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIAN 358
              G      + G   ++   G+                G       +G        G   
Sbjct: 779  PTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG 838

Query: 359  EDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAH 418
            E    G   +    G   +   +G    D  HG        + +  P   +G        
Sbjct: 839  ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHG----PPGERGLPGPQGPNGFPGPKGPP 894

Query: 419  GIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANED 478
            G   +D   G   +    G   +    G       QG A E    G        G   E 
Sbjct: 895  GPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQ 954

Query: 479  AVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVA 538
             + G A +    G      A     P   RG   E    G A      G        G A
Sbjct: 955  GLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPA 1014

Query: 539  NEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVH 598
                  G A               G       +G+  E    G    D   GV   V + 
Sbjct: 1015 GSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRD---GVQGPVGLP 1071

Query: 599  GVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANE 658
            G A      GVA ED   G   +   +G       HG        G V +    G    E
Sbjct: 1072 GPA---GPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAG-ADGE 1127

Query: 659  DAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGI 718
              A+       A G       +G       QG+      +G   +V   G       +G 
Sbjct: 1128 PGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGP 1187

Query: 719  ANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEV 778
            A  + A G        G        G   E  + G+  E  V+G   E   +G   E   
Sbjct: 1188 AGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGE---RGEKGESGQ 1244

Query: 779  QGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANE 838
             G       +G   +D   G    V   G        G   +D A+G   ED   G   +
Sbjct: 1245 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGED---GEPGQ 1301

Query: 839  DAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANE 898
              + G   E    G   +    G    E   G    +    AI  P     +   G A +
Sbjct: 1302 PGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1361

Query: 899  VAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVA 958
                G+    +   + +    G T +              +  +  A+G        G+ 
Sbjct: 1362 PGPDGL--RGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLI 1419

Query: 959  NEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEV 997
                 QG   E   +G+       G   E  + G +  +
Sbjct: 1420 GPPGEQG---EKGDRGLPGPQGSPGQKGEMGIPGASGPI 1455



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 195/1042 (18%), Positives = 294/1042 (28%), Gaps = 72/1042 (6%)

Query: 392  VVANEDAAQAIAK--------PDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDA 443
            V A E  AQAI +        P    G        G       +G + ++   G      
Sbjct: 467  VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQG 526

Query: 444  VQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAK 503
            + G   +   +G A  D A+G+  +  V+G    D + G+  E    G            
Sbjct: 527  LTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 586

Query: 504  PDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHG 563
             D  RG   E+  +G+  E    G+       G+       G+           P    G
Sbjct: 587  EDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPG 646

Query: 564  IANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANE-- 621
               +  T G        G        G   +  + G+   D   G   ++   G      
Sbjct: 647  PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQG 706

Query: 622  -DAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAH 680
                QG        GV   D ++G+       G    ED            G   EV   
Sbjct: 707  PSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG----EDGFPGFKGDIGVKGDRGEVGVP 762

Query: 681  GIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANED 740
            G   ED  +G        G        G   +  V G+      QG       +G     
Sbjct: 763  GSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQG------PKGSLGFP 816

Query: 741  AVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIA 800
               G + E  A G++ +    G   E    G   +   +G   +   +G +  D  HG  
Sbjct: 817  GFPGASGEKGARGLSGK---SGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPP 873

Query: 801  NEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQ 860
             E    G+       G        G   +D + G        G   EV   G T      
Sbjct: 874  GE---RGLPGPQGPNGFPGPKGPPGPPGKDGLPG------HPGQRGEVGFQGKTGPPGPP 924

Query: 861  GVVNEEALHGVVA--NEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAA 918
            GVV  +   G      E        P    G+   G A +   +G      A G  KD  
Sbjct: 925  GVVGPQGAAGETGPMGERGHPGPPGPPGEQGL--PGTAGKEGTKGDPGPPGAPG--KDGP 980

Query: 919  HGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANE 978
             G+      + +        +   +   G      + G   E  A G    +   G    
Sbjct: 981  AGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPG---ERGAAGSGGPIGPPGRPGP 1037

Query: 979  DAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGI 1038
                G A E  V G    +   G   +D +QG        G+       G+A ED  +G 
Sbjct: 1038 QGPPGAAGEKGVPGEKGPI---GPTGRDGVQGPV------GLPGPAGPPGVAGEDGDKGE 1088

Query: 1039 ANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAV 1098
              +   +G       HG        G   +  A G   E  A+G       +G   ++  
Sbjct: 1089 VGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKG---DEGT 1145

Query: 1099 HGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANE 1158
             G       +G      +QG+      +G   +V   G       +G A  + A G    
Sbjct: 1146 RGF------NGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGP 1199

Query: 1159 VAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAI 1218
                G       +G   E  + GI  E  V+G   E    G   E    G          
Sbjct: 1200 PGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGE---RGEKGESGQPGEPGPPGPKGP 1256

Query: 1219 AKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAA 1278
               D  +G    V   G        G   +D A G   E    G   +    G   E+  
Sbjct: 1257 TGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG---QPGSPGPTGENGP 1313

Query: 1279 QGIAKEDAVQGIANEDAAQG--IAKEDP-VQGVANEDPIQGVANEVEVQGVAHEDAVQGI 1335
             G   +    G    +  QG   AK DP   G   +    G A      G      + G 
Sbjct: 1314 PGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGS 1373

Query: 1336 ANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPV 1395
              +    G   +    G         +  +  A+G      + G+      QG   E   
Sbjct: 1374 VGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQG---EKGD 1430

Query: 1396 QGVANEDAVQGVANEVEVQGVA 1417
            +G+       G   E+ + G +
Sbjct: 1431 RGLPGPQGSPGQKGEMGIPGAS 1452



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 190/1017 (18%), Positives = 273/1017 (26%), Gaps = 73/1017 (7%)

Query: 916  DAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGV 975
            D A G+  +   +     D    +  E   +G        G   ED  +G   E+  +G+
Sbjct: 543  DGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGL 602

Query: 976  ANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAA 1035
              E    G+       G+     V+G+      +G        G   +    G       
Sbjct: 603  PGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGP 662

Query: 1036 QGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANE 1095
            QG       +G   +    G+   D   G   ++   G        G        G    
Sbjct: 663  QGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGV 722

Query: 1096 DAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGI 1155
              V G+       G   ED   G   +  V+G   EV V G   ED  +G        G 
Sbjct: 723  KGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEG---PKGRTGP 779

Query: 1156 ANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAA 1215
              +    G+  E    G+       G       +G        G + E  A G++ +   
Sbjct: 780  TGDPGPPGLMGEKGKLGV---PGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGP 836

Query: 1216 HAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANE 1275
                 P   RG   +   +G   +  A G +  D  HG   E    G+       G    
Sbjct: 837  RGERGPTGPRG---QRGPRGATGKSGAKGTSGGDGPHGPPGE---RGLPGPQGPNGFPGP 890

Query: 1276 DAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGI 1335
                G   +D + G   +    G   +    G       QG A E    G        G 
Sbjct: 891  KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGP 950

Query: 1336 ANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPV 1395
              E    G A ++  +G      A         +G   E  + G A     +G       
Sbjct: 951  PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP 1010

Query: 1396 QGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANE 1455
             G A     +G A      G       QG        G+  E    G    D  QG    
Sbjct: 1011 PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQG---- 1066

Query: 1456 DAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGI 1515
                G+       G+A ED   G   +    G       H    P    G   +    G 
Sbjct: 1067 --PVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAG- 1123

Query: 1516 ATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAV 1575
                 ADG   E  A G      A+G       +G      +QG+       G + E   
Sbjct: 1124 -----ADG---EPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGL------PGPSGEKGE 1169

Query: 1576 QGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIAN 1635
             G V                    P    G A    A          G       +G   
Sbjct: 1170 TGDV-------------GPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG 1216

Query: 1636 EVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHG 1695
            E  + GI  E  V+G   E   +G   E    G       +G   +D   G    V   G
Sbjct: 1217 ESGSPGIQGEPGVKGPRGERGEKG---ESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPG 1273

Query: 1696 VANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDA 1755
                    G   +D  +G       +G   E    G       +G    +   G A    
Sbjct: 1274 DPGPPGEGGPRGQDGAKG------DRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPG 1327

Query: 1756 AQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIAT 1815
            ++G       +G             V   G A +        PD  RG+   V  QG   
Sbjct: 1328 SEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPG------PDGLRGLPGSVGQQGRPG 1381

Query: 1816 EDVADGIP---NEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVE 1872
                 G P         G+  +  A G      + G+      QG   +  + G      
Sbjct: 1382 ATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPG------ 1435

Query: 1873 VQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQG 1929
             QG   +    GI       G        G A    A+        +G   E  VQG
Sbjct: 1436 PQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKG---EKGVQG 1489



 Score = 88.6 bits (218), Expect = 7e-17
 Identities = 172/896 (19%), Positives = 247/896 (27%), Gaps = 79/896 (8%)

Query: 654  VVANEDAAQAIAK--------PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVA 705
            V A E  AQAI +        P    G        G       +G + +   QG      
Sbjct: 467  VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQG 526

Query: 706  AHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVAN 765
              G   +   +G A  D A+G+  +  V+G    D + G+  E    G      + G   
Sbjct: 527  LTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 586

Query: 766  EDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQG 825
            ED  +G   E+  +G+  E   +G+       GI       GV   D  QG       QG
Sbjct: 587  EDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIP---GPPGVRGMDGPQGPKGSLGPQG 643

Query: 826  VANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPD 885
                    G        G    +  HG   E   QG   +  L G+  ++       K  
Sbjct: 644  EPGPPGQQGTPGTQGLPGPQGAIGPHG---EKGPQG---KPGLPGMPGSDGPPGHPGKEG 697

Query: 886  AAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAA 945
                  N+G +      G        G+                                
Sbjct: 698  PPGTKGNQGPSGPQGPLGYPGPRGVKGV-------------------------------- 725

Query: 946  QGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHK 1005
             G+       G   ED   G   ++  +G   E  V G   ED  +G        G    
Sbjct: 726  DGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGP 785

Query: 1006 DAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGI 1065
              + G   +    G+       G       +G        G + E  A G+S +   +G 
Sbjct: 786  PGLMGEKGKLGVPGLP------GYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG- 838

Query: 1066 ANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAV 1125
              E    G   +   +G   +   +G +  D  HG   E            +G+      
Sbjct: 839  --ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGE------------RGLPGPQGP 884

Query: 1126 QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHE 1185
             G        G   +D + G   +    G   +    G       QG A E    G    
Sbjct: 885  NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 944

Query: 1186 DAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGI 1245
                G   E  + G A +    G      A     P   RG   E    G A      G 
Sbjct: 945  PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 1004

Query: 1246 ANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPV 1305
                   G A      G +      G       QG       +G+  E    G    D V
Sbjct: 1005 EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGV 1064

Query: 1306 QG-VANEDPI--QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDI 1362
            QG V    P    GVA E   +G   +   +G       HG        G   +  A   
Sbjct: 1065 QGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGA 1124

Query: 1363 ANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAV 1422
              E  A+G       +G        G      +QG+      +G   +V   G       
Sbjct: 1125 DGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGP 1184

Query: 1423 QGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE 1482
            +G A  + A G        G       +G   E  + GI  E  V+G   E    G + +
Sbjct: 1185 RGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQ 1244

Query: 1483 ------VAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHG 1532
                      G   +D       P    G        G   +D A G   ED   G
Sbjct: 1245 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG 1300



 Score = 87.4 bits (215), Expect = 1e-16
 Identities = 177/965 (18%), Positives = 263/965 (27%), Gaps = 65/965 (6%)

Query: 1306 QGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANE 1365
            +G A  D  +G+  +  V+G    D + G+  E    G        G   ED  +    E
Sbjct: 537  RGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGE 596

Query: 1366 DAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGI 1425
               +G+  E   +G+       GI     V+G+   D  QG    +  QG       QG 
Sbjct: 597  IGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGM---DGPQGPKGSLGPQGEPGPPGQQGT 653

Query: 1426 ANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAA 1485
                   G    +  HG        G+     + G       +G        G +     
Sbjct: 654  PGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPS---GP 710

Query: 1486 HGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANE 1545
             G         +   D  RG+      +G            ED   G   ++  +G   E
Sbjct: 711  QGPLGYPGPRGVKGVDGIRGLKGHKGEKG------------EDGFPGFKGDIGVKGDRGE 758

Query: 1546 VAVHGVAIEDAVQGVVKEVTAHGVANEDAV---QGVVNEDALHSVVANEDAAQAIAKPDA 1602
            V V G   ED  +G        G      +   +G +    L      +    ++  P  
Sbjct: 759  VGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGF 818

Query: 1603 AHGIANEVAAHSIANKDAAQGIAN------QDAAQGIANEVAAHGISKEDAVQGIANEDA 1656
              G + E  A  ++ K   +G         Q   +G   +  A G S  D   G   E  
Sbjct: 819  P-GASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGE-- 875

Query: 1657 AQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVAN 1716
             +G+       G        G   +D + G        G   E   QG        GV  
Sbjct: 876  -RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHP------GQRGEVGFQGKTGPPGPPGV-- 926

Query: 1717 EVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHS 1776
             V  QG A E    G        G   E    G A ++  +G        G      +  
Sbjct: 927  -VGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRG 985

Query: 1777 VAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVA 1836
               E    G A          P    G A     +G A      G P      G      
Sbjct: 986  FPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAG 1045

Query: 1837 AHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIAN 1896
              G+  E    G    D  QG     P+ G+       GVA ED  +G   +    G   
Sbjct: 1046 EKGVPGEKGPIGPTGRDGVQG-----PV-GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKG 1099

Query: 1897 EDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQG 1956
                 G            +  A G   E   +G      A+G   ++  +G        G
Sbjct: 1100 NKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKG---DEGTRGF------NG 1150

Query: 1957 IANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDA 2016
                +   G+      +G   +    G       +G A  +   G            P  
Sbjct: 1151 PPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPG 1210

Query: 2017 ARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVA 2076
             +G   E  + GI  E    G   E    G + +        P    G  ++G       
Sbjct: 1211 EKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTG--DDGPKGNPGP 1268

Query: 2077 DGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEV 2136
             G   D   G   E   +    QD A G   ED   G        G        G     
Sbjct: 1269 VGFPGDP--GPPGEGGPRG---QDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPA 1323

Query: 2137 AAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVA 2196
             + G       +G   +  A G   +    G A      G      + G   +    G  
Sbjct: 1324 GSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGAT 1383

Query: 2197 NEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQ 2256
             +    G        G+  +  A+G   E    G+   +   G   E   R +     + 
Sbjct: 1384 GQAGPPGPVGPPGLPGLRGDAGAKG---EKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSP 1440

Query: 2257 GIANE 2261
            G   E
Sbjct: 1441 GQKGE 1445



 Score = 85.5 bits (210), Expect = 6e-16
 Identities = 192/1049 (18%), Positives = 293/1049 (27%), Gaps = 76/1049 (7%)

Query: 67   GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126
            G T      G       +G + +    G        G   +   +G A    A+G+  + 
Sbjct: 493  GYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDP 552

Query: 127  AVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIA 186
             V+G    D + G+  E   +G        G   ED  +G   E   + +  E   + + 
Sbjct: 553  GVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLL 612

Query: 187  NEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQ 246
                  GI     V+G+      +G        G   +    G       QG       +
Sbjct: 613  GPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEK 672

Query: 247  GVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 306
            G   +  + G+   D   G   +    G        G       QG       +G+   D
Sbjct: 673  GPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSG------PQGPLGYPGPRGVKGVD 726

Query: 307  AVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVA 366
             + G+       G   ED            G   EV   G   ED  +G        G  
Sbjct: 727  GIRGLK---GHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTG-- 781

Query: 367  KEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAA 426
             +    G+  E    GV     L G    +    ++  P    G + E  A G++ +   
Sbjct: 782  -DPGPPGLMGEKGKLGV---PGLPGYPGRQGPKGSLGFP-GFPGASGEKGARGLSGKSGP 836

Query: 427  QGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKE 486
            +G        G   +   +G   +  A+G +  D   G   E   +G+      +G    
Sbjct: 837  RGERGPTGPRG---QRGPRGATGKSGAKGTSGGDGPHGPPGE---RGLPGPQGPNGFPGP 890

Query: 487  VAAHGVANKDA--AHAIAKPDAA-------RGIANEVAAQGIATEDVADGIANEDAVHGV 537
                G   KD    H   + +          G    V  QG A E    G        G 
Sbjct: 891  KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGP 950

Query: 538  ANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAV 597
              E    G A ++       P  A G       +G   E    G A      G       
Sbjct: 951  PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP 1010

Query: 598  HGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVAN 657
             G A     +G A      G       QG        GV  E    G    D + G V  
Sbjct: 1011 PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPV-- 1068

Query: 658  EDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQG 717
                          G+       G+A ED  +G   +   +G       HG        G
Sbjct: 1069 --------------GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIG 1114

Query: 718  IANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVE 777
               +  A G   E   +G        G       +G      +QG+      +G   +V 
Sbjct: 1115 PVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVG 1174

Query: 778  VQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVAN 837
              G       +G A  + A G        G       +G   E  + G+  E  V G   
Sbjct: 1175 PMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRG 1234

Query: 838  EDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVAN 897
            E   +G +      G   E    G        G   N      +  P         G   
Sbjct: 1235 ERGEKGES------GQPGEPGPPGPKGPTGDDGPKGNPG---PVGFPGDPGPPGEGGPRG 1285

Query: 898  EVAAQGIATEDVADGIAKDAAHGITKEEAAQA-IAKQDAAHSITNE--DAAQGVANEDAA 954
            +  A+G   ED   G  +  + G T E      + K+  A S  +E     +G   +  A
Sbjct: 1286 QDGAKGDRGEDGEPG--QPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGA 1343

Query: 955  HGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANE 1014
             G   +    G A      G      + G   +    G   +    G      + G+  +
Sbjct: 1344 IGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGD 1403

Query: 1015 DAAH------GIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGIS------KEDAV 1062
              A       G+   +   G   E   +G+     + G   E+   G S          +
Sbjct: 1404 AGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGL 1463

Query: 1063 QGIANEDAAQGIANEDAAQGIAHEDAVQG 1091
             G A    A+G       +G   E  VQG
Sbjct: 1464 PGPAGPKGAKGATGPGGPKG---EKGVQG 1489



 Score = 82.0 bits (201), Expect = 6e-15
 Identities = 207/1170 (17%), Positives = 313/1170 (26%), Gaps = 63/1170 (5%)

Query: 49   PYEDTVH--DIANEDADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANE-VAAHGVA 105
            PY+ T    D   E+ +    ++ E A  G A     +G+  E     V    +   G  
Sbjct: 343  PYDYTYGYGDDYREETELGPALSAETAHSGAAAH-GPRGLKGEKGEPAVLEPGMLVEGPP 401

Query: 106  NEDAAQGVANEVAAQGVANEDAVQGVANEDAVQGVANEDAVQGIANEDAA----HGIANE 161
              +   G+      QG        G        G+   D   G            G    
Sbjct: 402  GPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGG 461

Query: 162  DAAQGIANEDAAQDIAKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGV 221
            D    +A ++A      + A   +       G +      G       +G + +   QG 
Sbjct: 462  DKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGP 521

Query: 222  ANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAA 281
                 + G   +   +G A     +G+  +  V+G    D   G+  E    G       
Sbjct: 522  RGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGL 581

Query: 282  QGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANE 341
             G   ED  +G   E   +G+  E    G+       G+        +   D   G    
Sbjct: 582  PGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGM---DGPQGPKGS 638

Query: 342  VATQGIATEDVADGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQA 401
            +  QG        G        G    +  HG   E   QG   +  L G+  ++     
Sbjct: 639  LGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHG---EKGPQG---KPGLPGMPGSDG---- 688

Query: 402  IAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDA 461
               P    G        G       QG        G+   D ++G+      +G   ED 
Sbjct: 689  ---PPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG---EDG 742

Query: 462  AQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGI-- 519
              G   +  V+G   E  V G   E    G   +        P    G   ++   G+  
Sbjct: 743  FPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPG 802

Query: 520  -ATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDV 578
                    G        G + E  A G++ +        P    G   +   +G   +  
Sbjct: 803  YPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRG---QRGPRGATGKSG 859

Query: 579  ADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVAN 638
            A G +  D  HG   E  + G    +   G        G        G   EV   G   
Sbjct: 860  AKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTG 919

Query: 639  EDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQ 698
                 GVV         A E             G   E    G A ++  +G      A 
Sbjct: 920  PPGPPGVVGPQG----AAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAP 975

Query: 699  GIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANED 758
            G        G   E  + G A     +G        G A      G A      G     
Sbjct: 976  GKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP 1035

Query: 759  PVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVA 818
              QG       +GV  E    G    D VQG        G+       GVA ED  +G  
Sbjct: 1036 GPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPV------GLPGPAGPPGVAGEDGDKGEV 1089

Query: 819  NEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAA 878
             +   +G       HG        G   +  A G   E   +G       H     ++  
Sbjct: 1090 GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQG----HFGAKGDEGT 1145

Query: 879  QAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHS 938
            +    P    G+  +G+      +G  T DV          G       +  A  + A  
Sbjct: 1146 RGFNGPPGPIGL--QGLPGPSGEKG-ETGDV-------GPMGPPGPPGPRGPAGPNGADG 1195

Query: 939  ITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVE 998
                    G        G   E  + G+  E   +G   E    G   E    G      
Sbjct: 1196 PQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGE---RGEKGESGQPGEPGPPG 1252

Query: 999  VQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISK 1058
             +G    D  +G        G        G   +D A+G   ED   G        G + 
Sbjct: 1253 PKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENG 1312

Query: 1059 EDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQG 1118
                 G      + G       +G   +    G   +    G A      G      + G
Sbjct: 1313 PPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPG 1372

Query: 1119 VANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDA 1178
               +    G   +    G      + G+  +  A G        G+      QG   E  
Sbjct: 1373 SVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQG---EKG 1429

Query: 1179 AQGIAHEDAVQGIANEDAVHGVAKEVAAHG 1208
             +G+       G   E  + G +  +   G
Sbjct: 1430 DRGLPGPQGSPGQKGEMGIPGASGPIGPGG 1459



 Score = 77.8 bits (190), Expect = 1e-13
 Identities = 162/913 (17%), Positives = 246/913 (26%), Gaps = 44/913 (4%)

Query: 1380 IANEDAAQGIAKEDP--VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANE 1437
            ++ E A  G A   P  ++G   E AV  +   + V+G    +   G+       G    
Sbjct: 364  LSAETAHSGAAAHGPRGLKGEKGEPAV--LEPGMLVEGPPGPEGPAGLIGPPGIQGNPGP 421

Query: 1438 VAAHGIANEDAAQGIANEDAAQGIAHEDAVQ----GIANEDAVHGVAKEVAAHGVANEDA 1493
            V   G        G+   D A G      +     G    D    VA + A      + A
Sbjct: 422  VGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQA 481

Query: 1494 AHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAI 1553
              A+  P    G        G        G + +    G        G   +    G A 
Sbjct: 482  RLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAG 541

Query: 1554 EDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKP---DAAHGIANEV 1610
             D  +G+  +    G    D + G+  E         +  AQ +  P   D   G   E+
Sbjct: 542  ADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRG----DTGAQGLPGPPGEDGERGDDGEI 597

Query: 1611 AAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIA 1670
                +  +   +G+       GI       G+      +G        G   +    G  
Sbjct: 598  GPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQ 657

Query: 1671 HEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQ 1730
                 QG        G   +    G+   D   G   ++   G        G        
Sbjct: 658  GLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYP 717

Query: 1731 GIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANED 1790
            G        GI       G   ED   G   +  V+G   E  V     E    G     
Sbjct: 718  GPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRT 777

Query: 1791 AAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIA 1850
                   P    G   ++   G+       G P      G        G S E   +G++
Sbjct: 778  GPTGDPGPPGLMGEKGKLGVPGLP------GYPGRQGPKGSLGFPGFPGASGEKGARGLS 831

Query: 1851 NEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQ 1910
             +   +G   E    G   +   +G   +   +G +  D  HG   E   +G+       
Sbjct: 832  GKSGPRG---ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGE---RGLPGPQGPN 885

Query: 1911 DIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANED 1970
                     G   +D + G   Q    G   +    G       QG A E    G     
Sbjct: 886  GFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHP 945

Query: 1971 AAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIA 2030
               G   E    G A ++  +G   +    G   +D    +      RG+       G+ 
Sbjct: 946  GPPGPPGEQGLPGTAGKEGTKG---DPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLK 1002

Query: 2031 TEDVADG------IANEDAAHGVANEDAAQAIAKPDAAHGIANE-GIATEDVADG-IAED 2082
              +   G         E  A G            P    G A E G+  E    G    D
Sbjct: 1003 GNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRD 1062

Query: 2083 AVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVA 2142
             VQG         +       G+  ED  +G   +   +G       HG        G  
Sbjct: 1063 GVQGPVG------LPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPV 1116

Query: 2143 NEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAH 2202
             +  A G   E  A+G       +G        G      +QG+      +G   +V   
Sbjct: 1117 GQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPM 1176

Query: 2203 GVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANED 2262
            G       +G A    A G        G        G   E  +  +  E   +G   E 
Sbjct: 1177 GPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGER 1236

Query: 2263 AAHGIANEDAVHG 2275
               G + +    G
Sbjct: 1237 GEKGESGQPGEPG 1249



 Score = 75.5 bits (184), Expect = 6e-13
 Identities = 165/933 (17%), Positives = 241/933 (25%), Gaps = 98/933 (10%)

Query: 1343 GIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANED 1402
            G    D    +A ++A      + A   +       G        G      ++G + + 
Sbjct: 457  GSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDL 516

Query: 1403 AVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIA 1462
              QG      + G   +   +G A  D A G+  +    G    D   G+  E   +G  
Sbjct: 517  GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDT 576

Query: 1463 HEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHA---------IAKPDAARGIANEVATQ 1513
                + G   ED   G   E+   G+  E              I  P   RG+      +
Sbjct: 577  GAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPK 636

Query: 1514 GIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANED 1573
            G      + G   E    G       QG+       G   E   QG   +    G+   D
Sbjct: 637  G------SLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQG---KPGLPGMPGSD 687

Query: 1574 AVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGI 1633
               G   ++       N+        P    G         +   D  +G+      +G 
Sbjct: 688  GPPGHPGKEGPPGTKGNQG-------PSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG- 739

Query: 1634 ANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAA 1693
                                ED   G   +   +G   E  V G   ED   G       
Sbjct: 740  --------------------EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGP 779

Query: 1694 HGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANE 1753
             G      + G   +  V G      + G       +G        G + E  A G++ +
Sbjct: 780  TGDPGPPGLMGEKGKLGVPG------LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGK 833

Query: 1754 DAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGI 1813
               +G   E    G   +        +  A G +  D  H    P   RG+       G 
Sbjct: 834  SGPRG---ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHG---PPGERGLPGPQGPNGF 887

Query: 1814 ATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEV 1873
                   G P +D   G        G   E   QG        G+      QG A E   
Sbjct: 888  PGPKGPPGPPGKDGLPG------HPGQRGEVGFQGKTGPPGPPGVVGP---QGAAGETGP 938

Query: 1874 QGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQ 1933
             G        G   E    G A ++  +G      A         +G   E  + G A  
Sbjct: 939  MGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGG 998

Query: 1934 DAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGI 1993
               +G        G A     +G A      G       QG       +G+  E    G 
Sbjct: 999  PGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP 1058

Query: 1994 ANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAA 2053
               D V G                 G+       G+A ED   G   +    G       
Sbjct: 1059 TGRDGVQGPV---------------GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGE 1103

Query: 2054 QAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQG 2113
                 P    G              + +    G   E  A+       A G        G
Sbjct: 1104 HGPPGPPGPIG-------------PVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNG 1150

Query: 2114 VTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVE 2173
                +  QG+       G   +V   G       +G A    A G        G      
Sbjct: 1151 PPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPG 1210

Query: 2174 VQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVAN 2233
             +G   +    GI  E   +G   E    G   E    G       +G   +D  +G   
Sbjct: 1211 EKGEPGESGSPGIQGEPGVKGPRGE---RGEKGESGQPGEPGPPGPKGPTGDDGPKGNPG 1267

Query: 2234 EVAVHGVANEDAARHMAKEDAAQGIANEDAAHG 2266
             V   G            +D A+G   ED   G
Sbjct: 1268 PVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG 1300



 Score = 56.6 bits (135), Expect = 3e-07
 Identities = 85/483 (17%), Positives = 132/483 (27%), Gaps = 13/483 (2%)

Query: 1798 PDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQG 1857
            P    G   +   +G A  D A G+P +    G        G+  E   +G        G
Sbjct: 524  PQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPG 583

Query: 1858 IAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAN--- 1914
               ED  +G   E+  +G+  E   +G+       GI      +G+      +       
Sbjct: 584  PPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQG 643

Query: 1915 EDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQG 1974
            E    G       QG+     A G   E   QG        G        G       +G
Sbjct: 644  EPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKG 703

Query: 1975 IANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDV 2034
                   QG       +G+   D + G+            D   G   ++  +G   E  
Sbjct: 704  NQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG---EDGFPGFKGDIGVKGDRGEVG 760

Query: 2035 ADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQ 2094
              G   ED   G            P    G   + +    +         +G        
Sbjct: 761  VPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK-LGVPGLPGYPGRQGPKGSLGFPGFP 819

Query: 2095 AIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEV 2154
              + +  A G++ +   +G   E    G   +    G   +  A G +  D   G   E 
Sbjct: 820  GASGEKGARGLSGKSGPRG---ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGE- 875

Query: 2155 AAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVA 2214
              +G+       G        G   KD + G   +    G   +    G       QG A
Sbjct: 876  --RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAA 933

Query: 2215 NEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVH 2274
             E    G        G   E  + G A ++  +       A G        G   E  + 
Sbjct: 934  GETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLP 993

Query: 2275 GIA 2277
            G A
Sbjct: 994  GTA 996



 Score = 37.7 bits (86), Expect = 0.14
 Identities = 73/380 (19%), Positives = 103/380 (27%), Gaps = 34/380 (8%)

Query: 1927 VQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQ---- 1982
            V+G    +   G+     +QG        G        G+   D A G            
Sbjct: 397  VEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRF 456

Query: 1983 GIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANED 2042
            G    D    +A ++A      + A  A+  P    G        G   +  + G+  E 
Sbjct: 457  GSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLG---QPGSPGLKGES 513

Query: 2043 AAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAED----------AVQGITNEEA 2092
               G       Q +  P    G    G A  D A G+  D           + G+  E+ 
Sbjct: 514  GDLGPQGPRGPQGLTGPPGKAG--RRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKG 571

Query: 2093 AQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANE------DA 2146
             +         G   ED  +G   E+  +G+  E    G+       G+         D 
Sbjct: 572  HRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDG 631

Query: 2147 AQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVAN 2206
             QG    +  QG       QG       QG+       G   E   QG        G   
Sbjct: 632  PQGPKGSLGPQGEPGPPGQQGTPG---TQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG 688

Query: 2207 EDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAK------EDAAQGIAN 2260
                 G       +G       QG        GV   D  R +        ED   G   
Sbjct: 689  PPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKG 748

Query: 2261 EDAAHGIANEDAVHGIANED 2280
            +    G   E  V G   ED
Sbjct: 749  DIGVKGDRGEVGVPGSRGED 768


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 248/1404 (17%), Positives = 395/1404 (28%), Gaps = 137/1404 (9%)

Query: 784  EDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQG 843
            ED   G+  +  + G        G       +G        G   E    G A      G
Sbjct: 1451 EDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPG 1510

Query: 844  VAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAA-QAIAKPDAAHGIANEGVANEVAAQ 902
            VA    A G        G   E+   G   +      A+A P    G  + G A    A 
Sbjct: 1511 VAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKG--DVGPAGPRGAT 1568

Query: 903  GIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDA 962
            G+  E    G+      G   +   +             +    G   +    G      
Sbjct: 1569 GVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVG 1628

Query: 963  AQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIAN 1022
             +G   EV  +G        G+  +   +G+     V+G   +   QG   ED  +G   
Sbjct: 1629 PRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPG 1688

Query: 1023 EVAAHGI-------------------ANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQ 1063
                 G                    A E    G   ++  +G   +    G   E  ++
Sbjct: 1689 SSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIE 1748

Query: 1064 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANE- 1122
            G       QG   +   +G A E   +G    D   G+  +  A G +  +   G A + 
Sbjct: 1749 GFRGPPGPQG---DPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDP 1805

Query: 1123 --DAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQ 1180
              D + G+  E  + G +    + G   ED   G+  +    G   ED  +G   +  A 
Sbjct: 1806 GRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGAS 1865

Query: 1181 GIAHEDAVQGIANEDAV--------------------HGVAKEVAAHGVANEDAAHAIAK 1220
            G    D  +G      +                     GV       G   E  +     
Sbjct: 1866 GREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQG 1925

Query: 1221 PDAARGIANE----------VAAQGIATEDVADGIANEDAAHGVANEV--AAHGISKEDA 1268
                RG+  E          +   GI    + + +   D + G    V     G   +  
Sbjct: 1926 LPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSG 1985

Query: 1269 VQGIANEDAAQGIAKEDAVQGIANEDAAQG-----IAKEDP-----VQGVANEDPIQGVA 1318
             QG   ++   G   E  ++G   +   QG     + +  P     + G   +  I G+ 
Sbjct: 1986 EQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLP 2045

Query: 1319 NEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDA-----AQDIANEDAAQGISK 1373
                  G A     +G   E    G    D   G+             ++ ++   G+S 
Sbjct: 2046 GRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSG 2105

Query: 1374 EDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANE----- 1428
            E    G+     A+G    +  QG   +  V G+  +    G   +D   G+  E     
Sbjct: 2106 EQGPPGL---KGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAG 2162

Query: 1429 -------DAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAK 1481
                       G    V  HG      A G+A     QG +      G        G+  
Sbjct: 2163 PEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPG-RGLTG 2221

Query: 1482 EVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQG 1541
               A G+        +  P  + G+  +V   G       DG + +D   G      + G
Sbjct: 2222 PTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPG 2281

Query: 1542 IANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPD 1601
            +   V   G        G    V   G   E    G +  D +    A  D  + +  P 
Sbjct: 2282 LPGPVGPKGEPGPTGAPGQA-VVGLPGAKGEKGAPGGLAGDLVGEPGAKGD--RGLPGPR 2338

Query: 1602 AAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIA 1661
               G A          +D  +G       +G               V G        G+ 
Sbjct: 2339 GEKGEAGRAGEPGDPGEDGQKGAPGPKGFKG----------DPGVGVPGSPGPPGPPGVK 2388

Query: 1662 NEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQ 1721
             +    G+     V G   +    G   E+   G + E  + G    + + G        
Sbjct: 2389 GDLGLPGLPGAPGVVGFPGQTGPRG---EMGQPGPSGERGLAGPPGREGIPGPLGPPGPP 2445

Query: 1722 GVAHEDAVQGIANEDAAHGI-----TNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHS 1776
            G        G+  +    G+       E    GI  ED   G      + G         
Sbjct: 2446 GSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERG 2505

Query: 1777 VAKEVAAHGVANEDAAHA-IAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEV 1835
               +V + G+  +    A I  P   RG   ++  +G        G+  +    G   + 
Sbjct: 2506 EKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERG------PRGLDGDKGPRGDNGDP 2559

Query: 1836 AAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIA 1895
               G   E   +G A     +G+       G A      G   +D V GI  E    G  
Sbjct: 2560 GDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFM 2619

Query: 1896 NEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQ 1955
                 +G      A  +  E   +G +      G+A      G   E  V G +     +
Sbjct: 2620 GPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMG---EPGVPGQSGAPGKE 2676

Query: 1956 GIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPD 2015
            G+       G   +   +G   E   +G        G +  D   G A          P 
Sbjct: 2677 GLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGND---GSAGPPGPPGSVGPR 2733

Query: 2016 AARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDV 2075
               G+  +   +G   E V  G      A G   E      A P    G A         
Sbjct: 2734 GPEGLQGQKGERGPPGERVV-GAPGVPGAPGERGEQGRPGPAGPRGEKGEA--------- 2783

Query: 2076 ADGIAEDAVQGITNEEAAQAIAKQ 2099
               + ED ++G   +E +Q  A Q
Sbjct: 2784 --ALTEDDIRGFVRQEMSQHCACQ 2805



 Score = 89.4 bits (220), Expect = 4e-17
 Identities = 229/1274 (17%), Positives = 371/1274 (29%), Gaps = 105/1274 (8%)

Query: 1013 NEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQ 1072
            +ED A G+  +  + G        G       +G    +   G   E    G A      
Sbjct: 1450 SEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLP 1509

Query: 1073 GIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEV 1132
            G+A    A+G        G   E    G   + A  G A   P +G   +    G     
Sbjct: 1510 GVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGP-KGEKGDVGPAGPRGAT 1568

Query: 1133 EVQG--------VAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAH 1184
             VQG        +  +   +G   +    G+       G +     +G        G   
Sbjct: 1569 GVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVG 1628

Query: 1185 EDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADG 1244
                 G   E    G   +    G A E     +      RG   E   QG   ED  +G
Sbjct: 1629 PRGRDGEVGEKGDEGPPGDPGLPGKAGE---RGLRGAPGVRGPVGEKGDQGDPGEDGRNG 1685

Query: 1245 IANEDAAHGVANEVAAHGI----------SKEDAVQGIANEDAAQGIAKEDAVQGIANED 1294
                    G   E    G           ++E    G   ++  +G   +  + G   E 
Sbjct: 1686 SPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGER 1745

Query: 1295 AAQGIAKEDPVQGVANEDP-IQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGI 1353
              +G       QG    DP ++G A E   +G    D   G+  +  A G +  + A G 
Sbjct: 1746 GIEGFRGPPGPQG----DPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGK 1801

Query: 1354 ANE---DAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANE 1410
            A +   D    +  E    G S    + G   ED   G+  ++   G   ED  +G   +
Sbjct: 1802 AGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGD 1861

Query: 1411 VEVQGVAHED------AVQGIANEDAAHGIANEVAA-----HGIANEDAAQGIANEDAAQ 1459
                G    D         GI       G+   V        G+      +G   E  ++
Sbjct: 1862 SGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSK 1921

Query: 1460 GIAHEDAVQGIANE-DAVHGVAKEVAAHGVA-----------NEDAAHAIAKPDAARGIA 1507
            G       +G+  E  +V  V + +   G+            +E +   +  P+  RG  
Sbjct: 1922 GEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPK 1981

Query: 1508 NEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAH 1567
             +   QG   ++   G   E    G   +   QG        G+A+ +            
Sbjct: 1982 GDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQG------PPGLALGE-----------R 2024

Query: 1568 GVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQ 1627
            G      + G   +  +  +           +P    G   E        +D   G+   
Sbjct: 2025 GPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRP-GERGERGEKGERGEQGRDGPPGLPGT 2083

Query: 1628 DAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1687
                G         +S ++   G++ E    G+     A+G    +  QG   +  V G+
Sbjct: 2084 PGPPG----PPGPKVSVDEPGPGLSGEQGPPGL---KGAKGEPGSNGDQGPKGDRGVPGI 2136

Query: 1688 AKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAA 1747
              +    G   +D   G+  E  + G   +  +QG       +G       HG      A
Sbjct: 2137 KGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQG------PRGPPGPVGGHGDPGPPGA 2190

Query: 1748 HGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANE 1807
             G+A     QG +      G         +     A G+        +  P  + G+  +
Sbjct: 2191 PGLAGPAGPQGPSGLKGEPGETGPPG-RGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQ 2249

Query: 1808 VAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGV 1867
            V   G       DG   +D   G      + G+      +G      A G A    + G 
Sbjct: 2250 VGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVG-LPGA 2308

Query: 1868 ANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAV 1927
              E    G    D V G        G+      +G A          ED  +G       
Sbjct: 2309 KGEKGAPGGLAGDLV-GEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGF 2367

Query: 1928 QGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHE 1987
            +G    D   G+       G        G+     A G+       G   E    G + E
Sbjct: 2368 KG----DPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGE 2423

Query: 1988 DAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIAT-----EDVADGIANED 2042
              + G    + + G            P  A G+  +    G+       E    GI  ED
Sbjct: 2424 RGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGED 2483

Query: 2043 AAHGVANEDAAQAIAKPDAAHGIANE--GIATEDVADGIAEDAV-QGITNEEAAQAIAKQ 2099
               G   ++  + +  P  + G   E   + +  +     + AV  G      A+    +
Sbjct: 2484 GRPG---QEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGE 2540

Query: 2100 DAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGV 2159
                G+  +   +G   +   +G   E    G A      G+       G A      G 
Sbjct: 2541 RGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGS 2600

Query: 2160 ANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVA---NE 2216
              +D V G+  E    G      ++G      A G+  E    G A      G+A    E
Sbjct: 2601 PGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGE 2660

Query: 2217 VAAQGVANEDAAQG 2230
            +   GV  +  A G
Sbjct: 2661 MGEPGVPGQSGAPG 2674



 Score = 87.4 bits (215), Expect = 1e-16
 Identities = 260/1449 (17%), Positives = 399/1449 (27%), Gaps = 130/1449 (8%)

Query: 75   QGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANE 134
            +G    +   G   E    G A      GVA    A+G        G   E    G   +
Sbjct: 1482 RGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGD 1541

Query: 135  DAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQGI 194
             AV G     AV G   E    G A    A G+  E     +        +  +   +G 
Sbjct: 1542 PAVVG----PAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLV-------LPGDPGPKGD 1590

Query: 195  SKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAV 254
              +    G+       G +     +G        G        G   E   +G   +  +
Sbjct: 1591 PGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGL 1650

Query: 255  QGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE 314
             G A E    G+       G   E   QG   ED   G       +G   E    G    
Sbjct: 1651 PGKAGE---RGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGR 1707

Query: 315  VAAHGV-ANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKEVTAHG 373
            +   G  A E         +   G   +    G   E   +G        G   +    G
Sbjct: 1708 LVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQG---DPGVRG 1764

Query: 374  VANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEV 433
             A E   +G    D   G+    D     A P   +G A +    G    D   G+  E 
Sbjct: 1765 PAGEKGDRGPPGLDGRSGL----DGKPGAAGPSGPNGAAGKA---GDPGRDGLPGLRGEQ 1817

Query: 434  AAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVA 493
               G S    + G   ED   G+  ++   G   ED  +G   E    G +      G  
Sbjct: 1818 GLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKG---EKGDSGASGREGRDGPK 1874

Query: 494  NKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAH 553
             +  A  I  P    G+   V   G     V  G        G        G+  E    
Sbjct: 1875 GERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGG-TGPKGDRGETGSKGEQGLPGERGLR 1933

Query: 554  AIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANED 613
               +P +   +   + T GI    + + +   D + G         + + +  +G   + 
Sbjct: 1934 --GEPGSVPNVDRLLETAGIKASALREIVETWDESSG-------SFLPVPERRRGPKGDS 1984

Query: 614  AVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGI 673
               G   ++   G   E    G   +   QG                      P  A G 
Sbjct: 1985 GEQGPPGKEGPIGFPGERGLKGDRGDPGPQG---------------------PPGLALGE 2023

Query: 674  ANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAV 733
                   G+A E    GI       G+       G +     +G   E   +G    D  
Sbjct: 2024 RGPPGPSGLAGEPGKPGI------PGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGP 2077

Query: 734  QGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANE 793
             G+       G         V+ ++P  G++ E   QG       +G    +  QG   +
Sbjct: 2078 PGLPGTPGPPG----PPGPKVSVDEPGPGLSGE---QGPPGLKGAKGEPGSNGDQGPKGD 2130

Query: 794  DAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGV 853
                GI  +    G   +D   G+  E    G   +  + G       +G    V  HG 
Sbjct: 2131 RGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQG------PRGPPGPVGGHGD 2184

Query: 854  TNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGI 913
                   G+                   A P    G+  E        +G+     A G+
Sbjct: 2185 PGPPGAPGLAGP----------------AGPQGPSGLKGEPGETGPPGRGLTGPTGAVGL 2228

Query: 914  -AKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAA 972
                   G+   + +  +  Q             G + +D   G      + G+   V  
Sbjct: 2229 PGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGP 2288

Query: 973  QGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANE 1032
            +G        G A    + G   E    G    D + G        G+       G A  
Sbjct: 2289 KGEPGPTGAPGQA-VVGLPGAKGEKGAPGGLAGDLV-GEPGAKGDRGLPGPRGEKGEAGR 2346

Query: 1033 DAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGI 1092
                G   ED  +G        G      V G        G+  +    G+     V G 
Sbjct: 2347 AGEPGDPGEDGQKGAPGPKGFKG-DPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGF 2405

Query: 1093 ANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAA 1152
              +    G   E+   G + E  + G    + + G        G        G+  +   
Sbjct: 2406 PGQTGPRG---EMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGD 2462

Query: 1153 HGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANE 1212
             G    V   G   E    GI  ED   G      + G        G   +V + G+  +
Sbjct: 2463 PG----VGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGD 2518

Query: 1213 DAAHA-IAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQG 1271
                A I  P   RG               A G   E    G+  +    G + +   +G
Sbjct: 2519 KGDSAVILGPPGPRG---------------AKGDMGERGPRGLDGDKGPRGDNGDPGDKG 2563

Query: 1272 IANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDA 1331
               E   +G A    ++G+       G A      G   +D + G+  E    G      
Sbjct: 2564 SKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRG 2623

Query: 1332 VQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAK 1391
            ++G      A G+  E   +G A       +A      G   E  V G +     +G+  
Sbjct: 2624 LKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMG---EPGVPGQSGAPGKEGLIG 2680

Query: 1392 EDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQG 1451
                +G   +   +G   E   +G        G +  D + G      + G    +  QG
Sbjct: 2681 PKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQG 2740

Query: 1452 IANEDAAQG--IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANE 1509
               E    G  +     V G   E    G        G   E    A    D  RG   +
Sbjct: 2741 QKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGE----AALTEDDIRGFVRQ 2796

Query: 1510 VATQGIATE 1518
              +Q  A +
Sbjct: 2797 EMSQHCACQ 2805



 Score = 86.7 bits (213), Expect = 3e-16
 Identities = 263/1476 (17%), Positives = 424/1476 (28%), Gaps = 145/1476 (9%)

Query: 419  GIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANED 478
            G A E   +G      + G+       G+A    A+G        G   E    G   + 
Sbjct: 1489 GEAGEKGERGPPGPAGSRGLP------GVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDP 1542

Query: 479  AVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVA 538
            AV G A      G   +      A P  A G+  E    G+        +  +    G  
Sbjct: 1543 AVVGPA----VAGPKGEKGDVGPAGPRGATGVQGERGPPGLV-------LPGDPGPKGDP 1591

Query: 539  NEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVH 598
             +    G+         + P    G        G       DG   E    G   +  + 
Sbjct: 1592 GDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLP 1651

Query: 599  GVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANE 658
            G A E  ++G      V G   E   QG   E   +G       +G   E    G     
Sbjct: 1652 GKAGERGLRGAPG---VRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRL 1708

Query: 659  DAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGI 718
                  A+     G   +    G   +    G   E   +G        G   +  V+G 
Sbjct: 1709 VDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQG---DPGVRGP 1765

Query: 719  ANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANE---DPVQGVANEDVVQGVANE 775
            A E   +G    D   G+  +    G +    A G A +   D + G+  E  + G +  
Sbjct: 1766 AGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGP 1825

Query: 776  VEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGV 835
              + G   ED   G+  ++   G   E    G   +  A G    D  +G   E    G+
Sbjct: 1826 PGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKG---ERGAPGI 1882

Query: 836  ANEDAAQGVAKEVTA-----------------HGVTNEDAVQGVVNEEALHGVVANEDAA 878
                   G+   V                    G T     QG+  E  L G        
Sbjct: 1883 LGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRG-------- 1934

Query: 879  QAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHS 938
            +  + P+    +   G+      + + T D               E +   +   +    
Sbjct: 1935 EPGSVPNVDRLLETAGIKASALREIVETWD---------------ESSGSFLPVPERRRG 1979

Query: 939  ITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVE 998
               +   QG   ++   G   E   +G   +   QG        G        G+A E  
Sbjct: 1980 PKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPG--LALGERGPPGPSGLAGE-- 2035

Query: 999  VQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHG--- 1055
                  K  I G+       G A      G   E   +G    D   G+       G   
Sbjct: 2036 ----PGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPG 2091

Query: 1056 --ISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANE 1113
              +S ++   G++ E    G+     A+G    +  QG   +  V G+  +    G   +
Sbjct: 2092 PKVSVDEPGPGLSGEQGPPGL---KGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQ 2148

Query: 1114 DPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGI 1173
            D   G+  E  + G   +  +QG                 G    V  HG      A G+
Sbjct: 2149 DGNPGLPGERGMAGPEGKPGLQG---------------PRGPPGPVGGHGDPGPPGAPGL 2193

Query: 1174 ANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAA 1233
            A     QG +      G        G+     A G+        +  P  + G+  +V  
Sbjct: 2194 AGPAGPQGPSGLKGEPGETGPPG-RGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGE 2252

Query: 1234 QGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIA---------KE 1284
             G       DG + +D   G      + G+      +G      A G A         ++
Sbjct: 2253 TGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEK 2312

Query: 1285 DAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGI 1344
             A  G+A +   +  AK D  +G+      +G A      G   ED  +G        G 
Sbjct: 2313 GAPGGLAGDLVGEPGAKGD--RGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKG- 2369

Query: 1345 ANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAV 1404
               D   G+                G+       G+       G   E    G + E  +
Sbjct: 2370 ---DPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGL 2426

Query: 1405 QGVANEVEVQGVAHEDAVQGIANEDAAHGIANE-----VAAHGIANEDAAQGIANEDAAQ 1459
             G      + G        G      A G+  +     V   G   E    GI  ED   
Sbjct: 2427 AGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRP 2486

Query: 1460 GIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHA-IAKPDAARGIANEVATQGIATE 1518
            G      + G        G   +V + G+  +    A I  P   RG   ++  +G    
Sbjct: 2487 GQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERG---- 2542

Query: 1519 DVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGV 1578
                G+  +    G   +   +G   E    G A    ++G++      G A      G 
Sbjct: 2543 --PRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGS 2600

Query: 1579 VNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVA 1638
              +D +   +  E        P    G      A  +  +   +G A      G+A    
Sbjct: 2601 PGKDGVPG-IRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKG 2659

Query: 1639 AHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVAN 1698
              G   E  V G +     +G+      +G   +   +G   E    G        G + 
Sbjct: 2660 EMG---EPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSG 2716

Query: 1699 EDPVQGVANEDAVQGVANEVEVQGVAHE-----DAVQGIANEDAAHGITNEVAAHGIANE 1753
             D   G        G      +QG   E     + V G      A G   E    G A  
Sbjct: 2717 NDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGP 2776

Query: 1754 DAAQGIA--HEDAVQGIANEDAVHSVAKEVAAHG--VANEDAAHAIAKPDAARGIANEVA 1809
               +G A   ED ++G   ++    +++  A  G  +A+          D A    + V 
Sbjct: 2777 RGEKGEAALTEDDIRGFVRQE----MSQHCACQGQFIASGSRPLPSYAADTAGSQLHAVP 2832

Query: 1810 AQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDA 1845
               ++  +  + +P ED  +   +E +       +A
Sbjct: 2833 VLRVSHAEEEERVPPEDDEYSEYSEYSVEEYQDPEA 2868



 Score = 83.2 bits (204), Expect = 3e-15
 Identities = 229/1245 (18%), Positives = 362/1245 (29%), Gaps = 145/1245 (11%)

Query: 67   GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126
            G+T      G +     +G        G        G   E   +G   +    G A E 
Sbjct: 1598 GLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGER 1657

Query: 127  AVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDI---------- 176
             ++G      V+G   E   QG   ED  +G       +G   E                
Sbjct: 1658 GLRGAPG---VRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPG 1714

Query: 177  AKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGI-----AKEDP-VQGVANEDPVQGV 230
            A+E        ++  +G   +  + G   E   +G       + DP V+G A E   +G 
Sbjct: 1715 AREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGP 1774

Query: 231  ANEDAVQGVANEVEVQGVAHEDAVQGIANE---DAAHGITNEVAAHGIANEDAAQGIANE 287
               D   G+  +    G +  +   G A +   D   G+  E    G +      G   E
Sbjct: 1775 PGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGE 1834

Query: 288  DAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANED------AAHAIAKPDAAHGIANE 341
            D   G+  ++   G   ED   G   +  A G    D       A  I  P    G+   
Sbjct: 1835 DGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGP 1894

Query: 342  VATQGIATEDVADGIANEDAAHGVAKEVTAHGVANEDAVQG----VVNEDAL---HGVVA 394
            V   G     V  G        G        G+  E  ++G    V N D L    G+ A
Sbjct: 1895 VGPPGQGFPGVPGG-TGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKA 1953

Query: 395  ----------NEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAV 444
                      +E +   +  P+   G   +    G   ++   G   E    G   +   
Sbjct: 1954 SALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGP 2013

Query: 445  QGIANEDAAQGIAHEDAAQGIAHE---DAVQGIANEDAVHGVAKEVAAHGVANKDAAHAI 501
            QG      A G        G+A E     + G+       G A      G   +      
Sbjct: 2014 QG--PPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGE 2071

Query: 502  AKPDAARGIANEVAAQG-----IATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIA 556
               D   G+       G     ++ ++   G++ E    G+       G   E  ++   
Sbjct: 2072 QGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGL------KGAKGEPGSNGDQ 2125

Query: 557  KPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAV- 615
             P    G+       GI  +    G   +D   G+  E  + G   +  +QG        
Sbjct: 2126 GPKGDRGV------PGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPV 2179

Query: 616  --HGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGI 673
              HG      A G+A      G A      G+  E    G        + +  P  A G+
Sbjct: 2180 GGHGDPGPPGAPGLA------GPAGPQGPSGLKGEPGETG-----PPGRGLTGPTGAVGL 2228

Query: 674  ANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGI------ 727
                   G+     + G+  +    G        G S +D  +G      + G+      
Sbjct: 2229 PGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGP 2288

Query: 728  --------AHEDAVQGI----ANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANE 775
                    A   AV G+      + A  G+A ++     A  D  +G+      +G A  
Sbjct: 2289 KGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGD--RGLPGPRGEKGEAGR 2346

Query: 776  VEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGV 835
                G   ED  +G        G    V   G        GV  +    G+     V G 
Sbjct: 2347 AGEPGDPGEDGQKGAPGPKGFKGDPG-VGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGF 2405

Query: 836  ANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAA-------- 887
              +   +G   E+   G + E  + G    E + G +       ++  P A+        
Sbjct: 2406 PGQTGPRG---EMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGD 2462

Query: 888  HGIANEGVANEVAAQGIATEDVADGIAKDAAHGIT-----------KEEAAQAIAKQDAA 936
             G+   G   E    GI  ED   G  ++   G+T           K +   A  K D  
Sbjct: 2463 PGVGLPGPRGERGEPGIRGEDGRPG--QEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKG 2520

Query: 937  HSIT--------------NEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVH 982
             S                 E   +G+  +    G   +   +G   E   +G A    + 
Sbjct: 2521 DSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLR 2580

Query: 983  GVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANED 1042
            G+       G A      G   KD + GI  E    G    +   G+  E   +G    D
Sbjct: 2581 GLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGF---MGPRGLKGERGVKGACGLD 2637

Query: 1043 AAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVA 1102
              +G   E    G       +G   E    G +     +G+      +G   +    G  
Sbjct: 2638 GEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQ 2697

Query: 1103 KEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAH 1162
             E    G        G +  D   G        G    + +QG   E    G    V A 
Sbjct: 2698 GEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPG-ERVVGAP 2756

Query: 1163 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAH 1207
            G+      +G        G   E     +  +D    V +E++ H
Sbjct: 2757 GVPGAPGERGEQGRPGPAGPRGEKGEAALTEDDIRGFVRQEMSQH 2801



 Score = 72.4 bits (176), Expect = 5e-12
 Identities = 203/1124 (18%), Positives = 323/1124 (28%), Gaps = 94/1124 (8%)

Query: 67   GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126
            G   E  ++G       QG   +    G A E    G    D   G+  +  A G +  +
Sbjct: 1740 GAPGERGIEGFRGPPGPQG---DPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPN 1796

Query: 127  AVQGVANE---DAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQ 183
               G A +   D + G+  E  + G +      G   ED   G+  ++       ED  +
Sbjct: 1797 GAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRK 1856

Query: 184  DIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANE--------DPVQGVANEDA 235
                +  A G    D  +G   E  A GI       G+             V G      
Sbjct: 1857 GEKGDSGASGREGRDGPKG---ERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKG 1913

Query: 236  VQGVANEVEVQGVAHEDAVQG----IANED---AAHGITNEVAAHGIANEDAAQG--IAN 286
             +G       QG+  E  ++G    + N D      GI        +   D + G  +  
Sbjct: 1914 DRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPV 1973

Query: 287  EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQG 346
             +  +G   +   QG   ++   G   E    G   +        P  A G        G
Sbjct: 1974 PERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQ--GPPGLALGERGPPGPSG 2031

Query: 347  IATEDVADGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDA-------A 399
            +A E    GI       G   E    G   E   +G   E    G               
Sbjct: 2032 LAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPG 2091

Query: 400  QAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHE 459
              ++  +   G++ E    G+     A+G        G   +  V GI  +    G   +
Sbjct: 2092 PKVSVDEPGPGLSGEQGPPGL---KGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQ 2148

Query: 460  DAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGI 519
            D   G+  E  + G   +  + G        G       H    P  A G+A     QG 
Sbjct: 2149 DGNPGLPGERGMAGPEGKPGLQG------PRGPPGPVGGHGDPGPPGAPGLAGPAGPQGP 2202

Query: 520  ATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVA 579
            +      G        G+     A G+        +  P  + G+  +V   G       
Sbjct: 2203 SGLKGEPGETGPPG-RGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGR 2261

Query: 580  DGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANE 639
            DG + +D   G        G+      +G        G A           V   G   E
Sbjct: 2262 DGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQA----------VVGLPGAKGE 2311

Query: 640  DAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQG 699
                G +  D +    A  D  + +  P    G A      G   ED  +G       +G
Sbjct: 2312 KGAPGGLAGDLVGEPGAKGD--RGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKG 2369

Query: 700  IANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDP 759
                V   G        G+  +    G+     V G   +    G   E+   G + E  
Sbjct: 2370 DPG-VGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRG---EMGQPGPSGERG 2425

Query: 760  VQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVAN 819
            + G    + + G        G        G+  +    G    V   G   E    G+  
Sbjct: 2426 LAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPG----VGLPGPRGERGEPGIRG 2481

Query: 820  EDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQ 879
            ED   G   ++   G+     ++G            E   +G V    L G   ++  + 
Sbjct: 2482 EDGRPG---QEGPRGLTGPPGSRG------------ERGEKGDVGSAGLKG---DKGDSA 2523

Query: 880  AIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAA-HGITKEEAAQAIAKQDAAHS 938
             I  P    G   +G   E   +G+  +    G   D    G   E   +  A       
Sbjct: 2524 VILGPPGPRGA--KGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRG 2581

Query: 939  ITNEDAAQGVANEDAAHGVANEDAAQGVANE------VAAQGVANEDAVHGVANEDAVQG 992
            +       G A      G   +D   G+  E      +  +G+  E  V G    D  +G
Sbjct: 2582 LLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKG 2641

Query: 993  VANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVA 1052
               E    G       +G   E    G +      G+      +G   +   +G   E  
Sbjct: 2642 DKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKG 2701

Query: 1053 AHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVAN 1112
              G        G +  D + G      + G    + +QG   E    G  + V A GV  
Sbjct: 2702 ERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPG-ERVVGAPGVPG 2760

Query: 1113 EDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIA 1156
                +G        G   E + +    ED ++G   ++ +   A
Sbjct: 2761 APGERGEQGRPGPAGPRGE-KGEAALTEDDIRGFVRQEMSQHCA 2803



 Score = 58.5 bits (140), Expect = 7e-08
 Identities = 186/1046 (17%), Positives = 305/1046 (29%), Gaps = 110/1046 (10%)

Query: 63   DAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGV 122
            D   G+  E  + G +      G   ED   G+  +    G   ED  +G   +  A G 
Sbjct: 1808 DGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGR 1867

Query: 123  ANEDAVQGVANEDAVQGVANEDAV-----------------------QGIANEDAAHGIA 159
               D  +G      + G      +                       +G        G+ 
Sbjct: 1868 EGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLP 1927

Query: 160  NEDAAQG----IANEDAAQDIA--KEDAAQDIA---NEDAAQGISKEDAVQGIANEDAAQ 210
             E   +G    + N D   + A  K  A ++I    +E +   +   +  +G   +   Q
Sbjct: 1928 GERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQ 1987

Query: 211  G-IAKEDPVQGVANEDPVQGVANEDAVQGVAN-EVEVQGVAHEDAVQGIANEDAAHGITN 268
            G   KE P+ G   E  ++G   +   QG     +  +G      + G   +    G+  
Sbjct: 1988 GPPGKEGPI-GFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPG 2046

Query: 269  EVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHG-----VAKEVAAHGVANE 323
                 G A     +G   E   +G    D   G+       G     V+ +    G++ E
Sbjct: 2047 RAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGE 2106

Query: 324  DAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKEVTAHGVANEDAVQGV 383
                 +     A G       QG   +    GI  +    G   +    G+  E  + G 
Sbjct: 2107 QGPPGL---KGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGP 2163

Query: 384  VNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDA 443
              +  L G        +    P   HG      A G+A     QG +      G +    
Sbjct: 2164 EGKPGLQG-------PRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPG 2216

Query: 444  VQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKD------- 496
             +G+     A G+       G+       G+  +    G        G + KD       
Sbjct: 2217 -RGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPG 2275

Query: 497  --AAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHA 554
               +  +  P   +G      A G A   +      + A  G+A ++     A  D    
Sbjct: 2276 VPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGD--RG 2333

Query: 555  IAKPDAAHGIANEVATQGIATEDVADGIANE-----DAAHGVANEVAVHGVAIEDAVQGV 609
            +  P    G A      G   ED   G         D   GV       G        G+
Sbjct: 2334 LPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGL 2393

Query: 610  ANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDA 669
                   GV       G   E+   G + E  + G    + + G +       ++  P A
Sbjct: 2394 PGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGA 2453

Query: 670  AHGIANE-----VAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAA 724
            + G+  +     V   G   E    GI  ED   G            ++  +G+     +
Sbjct: 2454 S-GLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPG------------QEGPRGLTGPPGS 2500

Query: 725  QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHE 784
            +G   E    G A      G +  +   G       +G   E   +G+  +   +G   +
Sbjct: 2501 RGERGEKGDVGSAGLKGDKGDSAVIL--GPPGPRGAKGDMGERGPRGLDGDKGPRGDNGD 2558

Query: 785  DAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGV 844
               +G   E    G A      G+       G A      G   +D V G+  E    G 
Sbjct: 2559 PGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGF 2618

Query: 845  AKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGI 904
               +   G+  E  V+G          +  E   +  A P    G+A  G   E+   G+
Sbjct: 2619 ---MGPRGLKGERGVKGACG-------LDGEKGDKGEAGPPGRPGLA--GHKGEMGEPGV 2666

Query: 905  ATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQ 964
              +  A G       G+   +  +    Q        E   +G        G +  D + 
Sbjct: 2667 PGQSGAPG-----KEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSA 2721

Query: 965  GVANEVAAQGVANEDAVHGVANEDAVQG--VANEVEVQGIAHKDAIQGIANEDAAHGIAN 1022
            G      + G    + + G   E    G  V     V G   +   QG        G   
Sbjct: 2722 GPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKG 2781

Query: 1023 EVAAHGIANEDAAQGIANEDAAQGIA 1048
            E A      ED  +G   ++ +Q  A
Sbjct: 2782 EAA----LTEDDIRGFVRQEMSQHCA 2803



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 86/461 (18%), Positives = 124/461 (26%), Gaps = 27/461 (5%)

Query: 1815 TEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQ 1874
            +ED A G+P +  + G        G       +G        G   E    G A    + 
Sbjct: 1450 SEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLP 1509

Query: 1875 GVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQD 1934
            GVA     +G        G   E    G   + A        A  G   E    G A   
Sbjct: 1510 GVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVG----PAVAGPKGEKGDVGPAGPR 1565

Query: 1935 AAQGIAKEDAVQGIA--NEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQG 1992
             A G+  E    G+    +   +G   +    G+       G +     +G        G
Sbjct: 1566 GATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPG 1625

Query: 1993 IANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDA 2052
                    G   E        P    G+  +   +G+       G   E    G   ED 
Sbjct: 1626 PVGPRGRDGEVGEKGDEG---PPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDG 1682

Query: 2053 AQAIAKPDAAHGIANEGIATE------DVADGIAEDAVQGITNEEAAQAIAKQDAAHGIT 2106
                       G   E           D   G  E    G   +E  +         G  
Sbjct: 1683 RNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAP 1742

Query: 2107 KEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQ 2166
             E   +G       QG   +    G A E    G    D   G+  +  A G +  +   
Sbjct: 1743 GERGIEGFRGPPGPQG---DPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAA 1799

Query: 2167 GVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANED 2226
            G A      G   +D + G+  E    G +      G   ED   G+  +    G   ED
Sbjct: 1800 GKA------GDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGED 1853

Query: 2227 AAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGI 2267
              +G   +    G    D  +    E  A GI       G+
Sbjct: 1854 GRKGEKGDSGASGREGRDGPK---GERGAPGILGPQGPPGL 1891



 Score = 38.1 bits (87), Expect = 0.10
 Identities = 86/462 (18%), Positives = 129/462 (27%), Gaps = 35/462 (7%)

Query: 1821 GIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHED 1880
            G+P    + G    V   G   E       +ED A G+  +    G        G     
Sbjct: 1424 GLPGLPGSPGPQGPVGPPGKKGEKG----DSEDGAPGLPGQPGSPGEQGPRGPPGAIGPK 1479

Query: 1881 AVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIA 1940
              +G        G   E    G A       +A    A+G        G   +    G  
Sbjct: 1480 GDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRP 1539

Query: 1941 KEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIA--HEDAVQGIANEDA 1998
             + AV G     A  G   E    G A    A G+  E    G+    +   +G   +  
Sbjct: 1540 GDPAVVG----PAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRG 1595

Query: 1999 VHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAK 2058
              G+         + P   +G        G       DG   E    G   +      A 
Sbjct: 1596 PIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAG 1655

Query: 2059 PDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEV 2118
                 G                   V+G   E+  Q    +D  +G       +G   E 
Sbjct: 1656 ERGLRGAPG----------------VRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEP 1699

Query: 2119 AAQGVANE--DAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQG 2176
               G      D   G A E    G   ++  +G   +    G   E  ++G       QG
Sbjct: 1700 GPPGPPGRLVDTGPG-AREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQG 1758

Query: 2177 IAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANE---DAAQGVAN 2233
                  ++G A E   +G        G+  +  A G +    A G A +   D   G+  
Sbjct: 1759 ---DPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRG 1815

Query: 2234 EVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVHG 2275
            E  + G +          ED   G+  ++   G   ED   G
Sbjct: 1816 EQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKG 1857



 Score = 37.0 bits (84), Expect = 0.23
 Identities = 81/413 (19%), Positives = 115/413 (27%), Gaps = 37/413 (8%)

Query: 1896 NEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQ 1955
            +ED A G+  +  +          G       +G        G   E    G A      
Sbjct: 1450 SEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLP 1509

Query: 1956 GIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPD 2015
            G+A    A G        G   E    G   + AV G     AV G   E      A P 
Sbjct: 1510 GVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVG----PAVAGPKGEKGDVGPAGPR 1565

Query: 2016 AARGIANEVAAQGIATE-------DVAD-------GIANEDAAHGVANEDAAQAIAKPDA 2061
             A G+  E    G+          D  D       G A      G   E        P  
Sbjct: 1566 GATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPG 1625

Query: 2062 AHGI-ANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAA 2120
              G    +G   E   +G   D   G+  +   + +       G   E   QG   E   
Sbjct: 1626 PVGPRGRDGEVGEKGDEGPPGDP--GLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGR 1683

Query: 2121 QGVANEDAAHGVANEVAAHGV----------ANEDAAQGVANEVAAQGVANEDAVQGVAN 2170
             G        G   E    G           A E    G   +   +G   +  + G   
Sbjct: 1684 NGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPG 1743

Query: 2171 EVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQG 2230
            E  ++G       QG   +   +G A E    G    D   G+  +  A G +  + A G
Sbjct: 1744 ERGIEGFRGPPGPQG---DPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAG 1800

Query: 2231 VANEVA---VHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVHGIANED 2280
             A +     + G+  E      +      G   ED   G+  ++   G   ED
Sbjct: 1801 KAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGED 1853


>gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]
          Length = 1714

 Score = 87.8 bits (216), Expect = 1e-16
 Identities = 167/949 (17%), Positives = 266/949 (28%), Gaps = 79/949 (8%)

Query: 606  VQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAA---- 661
            V G   +  + G+      QG        G+     + G+  E  + G   N  +     
Sbjct: 547  VPGEKGDQGLSGLMGPPGMQG------DKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPG 600

Query: 662  -QAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIAN 720
             Q +A P+   G      A G        G    +  +GI       G        G   
Sbjct: 601  RQGLAGPEGNPG---PKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFG 657

Query: 721  EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQG 780
            +    G+     + G        G+   V   G      + G        G++    + G
Sbjct: 658  DRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGP------MGLSGNKGLPG 711

Query: 781  IAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDA 840
            I  +   QG A E    G   +  A G+      +G   +    G   +  + G +    
Sbjct: 712  IKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRG---KSGPSGQTGDPGLQGPSGPPG 768

Query: 841  AQGVAKEVTAHGVTNEDAVQGVVNEEA------LHGVVANEDAAQAIAKPDAAHGIANEG 894
             +G   ++   G    +  +G++          L G    E    A  +         +G
Sbjct: 769  PEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKG 828

Query: 895  VANEVAAQGIATEDVADG----IAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVAN 950
             A E   +G+  E    G    I +    G+  E        +        E  + G   
Sbjct: 829  YAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKG------ERGSPGPLG 882

Query: 951  EDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQG 1010
                 GV       GV   +   G+       G       +G        G+  +  IQG
Sbjct: 883  PQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQG 942

Query: 1011 IANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDA 1070
               E    G        G       +G   +   QG+       G+  E  ++G+  +  
Sbjct: 943  AKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVG 1002

Query: 1071 AQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVAN 1130
              G    +   G   E  +QG        G A  V   G        G   E+ +QG   
Sbjct: 1003 PPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQG--- 1059

Query: 1131 EVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQG 1190
                 G+      +G+  ED   G        G        G+   +   GI  +    G
Sbjct: 1060 ---KDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPG 1116

Query: 1191 IANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGI----- 1245
               +    G   EV + G   +      + P  ARG    V   G+   D   GI     
Sbjct: 1117 KKGDKGQIGPTGEVGSRGPPGKIGK---SGPKGARGTRGAVGHLGLMGPDGEPGIPGYRG 1173

Query: 1246 -ANEDAAHGVANEVAAHGISKEDAV----------------QGIANEDAAQGIAKEDAVQ 1288
               +    G+       G   ED+                 QG   E  A+G      V 
Sbjct: 1174 HQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVP 1233

Query: 1289 GIANEDAAQGIAKE---DPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIA 1345
            G+      QG   E      QG+  E   +G   +    G + +  + G+       GI 
Sbjct: 1234 GLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQ 1293

Query: 1346 NEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQ 1405
                A GI+          +    GI       G+A      G+       G+     +Q
Sbjct: 1294 GYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGS---SGLPGSPGIQ 1350

Query: 1406 GVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHED 1465
            G   E   QG+  +  +QG      A G        G+  +    G+      QG     
Sbjct: 1351 GPKGE---QGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPK 1407

Query: 1466 AVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQG 1514
              +G A    + G    +   G         I  P    G   E   +G
Sbjct: 1408 GPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRG 1456



 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 174/998 (17%), Positives = 285/998 (28%), Gaps = 101/998 (10%)

Query: 1298 GIAKEDPVQGVANEDPIQGVANEVEVQG---VAHEDAVQGIANEDAAHGIANEDAAQGIA 1354
            G +   PV G   +  + G+     +QG   +     + G+  E    G A    + G  
Sbjct: 540  GFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYP 599

Query: 1355 NEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAV---QGVANEV 1411
                 Q +A  +   G        G   E    G   E  + G+  +      QG   + 
Sbjct: 600  GR---QGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDF 656

Query: 1412 EVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIA 1471
              +G A  D   G+       G      + G        GI       G++    + GI 
Sbjct: 657  GDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGP---MGLSGNKGLPGIK 713

Query: 1472 NEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAH 1531
             +    G A E+   G   +  A  +  P   RG +               G   +    
Sbjct: 714  GDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGP------------SGQTGDPGLQ 761

Query: 1532 GVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVA-- 1589
            G +     +G   ++ + G    +  +G++      G       QG          +   
Sbjct: 762  GPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPR 821

Query: 1590 NEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQ 1649
             +   +  A      G+  EV       K    G        G+  EV   G   E   +
Sbjct: 822  GKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPV------GLPGEVGMTGSIGEKGER 875

Query: 1650 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANED 1709
            G       QG       +G+       G+       G+   V A G       +G     
Sbjct: 876  GSPGPLGPQG------EKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSR 929

Query: 1710 AVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIA 1769
               G+  E  +QG   E   QG        G T      G   +   QG+      +G+ 
Sbjct: 930  GPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLP 989

Query: 1770 NEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAH 1829
             E  +  +  +V   G                     E+  +G    +   G+  E  A 
Sbjct: 990  GEPGLRGLQGDVGPPG---------------------EMGMEGPPGTEGESGLQGEPGAK 1028

Query: 1830 GVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANED 1889
            G      + G + E  ++G       +G+  +D ++GV      +G+  ED  +G     
Sbjct: 1029 GDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGG---RGLPGEDGEKGEMGLP 1085

Query: 1890 AAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIA 1949
               G        G+   +    I  +    G   +    G   +  ++G        G +
Sbjct: 1086 GIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRG---PPGKIGKS 1142

Query: 1950 NEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAH 2009
                A+G    V   G+   D   GI      QG   +    G+       G   ED+  
Sbjct: 1143 GPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQG---QPGPSGLPGPKGEKGYPGEDST- 1198

Query: 2010 AIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEG 2069
             +  P   RG    V  QG   E  A+G        G+      Q    P    G   E 
Sbjct: 1199 -VLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQG---PPGEPGDQGE- 1253

Query: 2070 IATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAA 2129
                           QG+  E  ++    +  A G + +    G+   +  +G+     A
Sbjct: 1254 ---------------QGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGA 1298

Query: 2130 HGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQG---IAHKDAIQGI 2186
             G++      G   +    G+       G+A      GV     + G   I      QG+
Sbjct: 1299 DGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGL 1358

Query: 2187 ANEDAAQGVANEVAAH---------GVANEDAAQGVANEVAAQGVANEDAAQGVANEVAV 2237
              +   QG      A          G+  +    GV      QG       +G A  V +
Sbjct: 1359 PGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGI 1418

Query: 2238 HGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVHG 2275
             G       R        +GI       G   E    G
Sbjct: 1419 SGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRG 1456



 Score = 82.0 bits (201), Expect = 6e-15
 Identities = 204/1212 (16%), Positives = 359/1212 (29%), Gaps = 90/1212 (7%)

Query: 1021 ANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAA 1080
            A ++  HGI    A + I  ED     +  V  H IS  +A      + ++    +++  
Sbjct: 324  AVDLTNHGI---QAKEMITEEDTQTNFSLSVTTHRIS--EAKMNTKEKFSSLLNMSDNIT 378

Query: 1081 QGIAHEDAVQGIA------------NEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGV 1128
            Q   H+D V G++             +D +  + K + A+   NE          ++  V
Sbjct: 379  Q---HDDRVTGLSLFKKMPSILPQIKQDTITNLKKAITANLHTNELMEMQPILNTSLHRV 435

Query: 1129 ANEVEVQGVAHEDA-VQGIANEDAAHGIAN--EVAAHGIANEDAAQGIANEDAAQGIAHE 1185
             NE  V    H D   +G    DA + I N  E   +     +    +   +  +G   +
Sbjct: 436  TNEPSVDN--HLDLRKEGEFYPDATYPIENSYETELYDYYYYEDLNTMLEMEYLRGPKGD 493

Query: 1186 DAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGI 1245
                G      + G + +    G+        +       G+      +G         +
Sbjct: 494  TGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLP------GLPGPKGPKGDPGFSPGQPV 547

Query: 1246 ANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPV 1305
              E    G++  +   G+  +   +G+       G+  E  + G A    + G      +
Sbjct: 548  PGEKGDQGLSGLMGPPGMQGD---KGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGL 604

Query: 1306 QGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANE 1365
             G       +G    +   G A +   +G        G       QG   +   +  A  
Sbjct: 605  AGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGL 664

Query: 1366 DAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGI 1425
            D + G+       G      + G     P+ G A      G++    + G+  +   QG 
Sbjct: 665  DGSPGLVGGTGPPGFPGLRGSVGPV--GPI-GPAGIPGPMGLSGNKGLPGIKGDKGEQGT 721

Query: 1426 ANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAA 1485
            A E    G   +  A G+      +G +      G   +  +QG +      G   ++  
Sbjct: 722  AGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTG---DPGLQGPSGPPGPEGFPGDIGI 778

Query: 1486 HGVANEDAAHAIAK---PDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGI 1542
             G    +    +     P    G+      +G        G   +    G A E   +G+
Sbjct: 779  PGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGL 838

Query: 1543 ANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVA--NEDAAQAIAKP 1600
              EV   G        G + E    G+  E  + G + E               + +   
Sbjct: 839  KGEVGDQGNI------GKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGY 892

Query: 1601 DAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGI 1660
                G+   +    +     A+G       +G        G+  E  +QG   E   QG 
Sbjct: 893  PGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGK 952

Query: 1661 ANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEV 1720
                   G       +G   +  + G+       G+  E  ++G+  +    G   E+ +
Sbjct: 953  RGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGD---VGPPGEMGM 1009

Query: 1721 QGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKE 1780
            +G    +   G+  E  A G      + G   E   +G       +G+  +D +  V   
Sbjct: 1010 EGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVP-- 1067

Query: 1781 VAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGI 1840
                G+  ED            G        G+   +   GIP +    G   +    G 
Sbjct: 1068 -GGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGP 1126

Query: 1841 SKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAA 1900
            + E   +G   +    G       +G    + + G   E  + G        G   +   
Sbjct: 1127 TGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGY------RGHQGQPGP 1180

Query: 1901 QGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANE 1960
             G+      +    ED+            +      +G       QG   E  A+G    
Sbjct: 1181 SGLPGPKGEKGYPGEDST-----------VLGPPGPRGEPGPVGDQGERGEPGAEGYKGH 1229

Query: 1961 VAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGI 2020
            V   G+      QG   E   QG       QG+  E    G   +  A   +      G+
Sbjct: 1230 VGVPGLRGATGQQGPPGEPGDQG------EQGLKGERGSEGNKGKKGAPGPSGKPGIPGL 1283

Query: 2021 ANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIA 2080
               +  +GI     ADGI+      G   +     I       G+A         A G  
Sbjct: 1284 QGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAG--------APG-- 1333

Query: 2081 EDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHG 2140
               V+G +    +  I       G+  +   QG      AQG        G+  +   +G
Sbjct: 1334 PPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYG 1393

Query: 2141 VANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVA 2200
            V      QG       +G A    + G    +  +G       +GI       G   E  
Sbjct: 1394 VQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKG 1453

Query: 2201 AHGVANEDAAQG 2212
              G       +G
Sbjct: 1454 FRGETGPQGPRG 1465



 Score = 82.0 bits (201), Expect = 6e-15
 Identities = 192/1127 (17%), Positives = 320/1127 (28%), Gaps = 108/1127 (9%)

Query: 66   HGITNEDAVQGVANEVAAQGVANEDAAHGVAN--EVAAHGVANEDAAQGVANEVAAQGVA 123
            H +TNE +V     ++  +G    DA + + N  E   +     +    +      +G  
Sbjct: 433  HRVTNEPSVDNHL-DLRKEGEFYPDATYPIENSYETELYDYYYYEDLNTMLEMEYLRGPK 491

Query: 124  NEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQ 183
             +    G      + G + +   +GI       G+      +G   +            Q
Sbjct: 492  GDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSP------GQ 545

Query: 184  DIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEV 243
             +  E   QG+S    + G       +G+     + G+  E  + G A      G     
Sbjct: 546  PVPGEKGDQGLS---GLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGR- 601

Query: 244  EVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDA---AQGIAHEDAVQ 300
              QG+A  +   G        G   E    G   E    GI  +      QG   +   +
Sbjct: 602  --QGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDR 659

Query: 301  GIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANED 360
            G A  D   G+   V   G            P    G A      G++      GI  + 
Sbjct: 660  GPAGLDGSPGL---VGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDK 716

Query: 361  AAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVA-----NEDAAQAIAKPDAAHGIANEV 415
               G A E+   G   +    G+     + G         +   Q  + P    G   ++
Sbjct: 717  GEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDI 776

Query: 416  AAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIA 475
               GI  ++  +G    +   G      ++G   E+   G   E   +G   +   +G A
Sbjct: 777  ---GIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRG---KPGQKGYA 830

Query: 476  NEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVH 535
             E    G+  EV   G   K             G+  EV   G      + G   E    
Sbjct: 831  GEPGPEGLKGEVGDQGNIGKIGETGPV------GLPGEVGMTG------SIGEKGERGSP 878

Query: 536  GVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEV 595
            G        GV        +  P    G+   V  +G        G        G+  E 
Sbjct: 879  GPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQ 938

Query: 596  AVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVV 655
             + G   E   QG      + G       +G   +    G+      +G+  E  L G+ 
Sbjct: 939  GIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQ 998

Query: 656  ANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAV 715
             +              G   E+   G    +   G+  E  A+G      + G + E  +
Sbjct: 999  GDV-------------GPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGL 1045

Query: 716  QGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANE 775
            +G       +G+  +D ++G+     + G   E    G+     + G        G+   
Sbjct: 1046 RGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPG---IIGPLGRSGQTGLPGP 1102

Query: 776  VEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGV 835
              + GI  +    G   +    G   EV + G   +    G       +G      + G 
Sbjct: 1103 EGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGP 1162

Query: 836  ANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHG-IANEG 894
              E    G        G   +    G+   +   G    +        P    G + ++G
Sbjct: 1163 DGEPGIPGY------RGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQG 1216

Query: 895  VANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAA 954
               E  A+G        G+                                +G   +   
Sbjct: 1217 ERGEPGAEGYKGHVGVPGL--------------------------------RGATGQQGP 1244

Query: 955  HGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANE 1014
             G   +   QG+  E  ++G   +    G + +  + G+      QG+     IQG    
Sbjct: 1245 PGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGL------QGLLGPKGIQGYHGA 1298

Query: 1015 DAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGI 1074
            D   G   ++   G       +G        G        G S      GI      QG+
Sbjct: 1299 DGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGL 1358

Query: 1075 ANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEV 1134
              +   QG       QG        G+  +   +GV      QG       +G A  V +
Sbjct: 1359 PGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGI 1418

Query: 1135 QGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQG 1181
             G       +G        GI       G   E   +G   E   QG
Sbjct: 1419 SGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGE---KGFRGETGPQG 1462



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 162/918 (17%), Positives = 263/918 (28%), Gaps = 63/918 (6%)

Query: 563  GIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANED 622
            G A  + + G        G        G    +   G A +   +G      + G     
Sbjct: 588  GFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFK 647

Query: 623  AAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGI 682
              QG   +    G A  D   G+V      G      +   +  P    GI   +   G+
Sbjct: 648  GRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVG-PIGPAGIPGPM---GL 703

Query: 683  ANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAV 742
            +      GI  +   QG A E+   G   +    G+      +G   +    G   +  +
Sbjct: 704  SGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRG---KSGPSGQTGDPGL 760

Query: 743  HGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANE 802
             G +      G   +  + G    +  +G+      +G      ++G   E+   G   E
Sbjct: 761  QGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGN---RGPPGPPGLKGTQGEEGPIGAFGE 817

Query: 803  VAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGV 862
            +   G   +    G    +  +G   +    G   E    G+  EV   G   E   +G 
Sbjct: 818  LGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGS 877

Query: 863  VNEEALHGVVANEDAAQAIAKPDAAHG-IANEGVANEVAAQGIATEDVADGIAKDAAHGI 921
                   G    E        P    G I   G+   V A+G                G 
Sbjct: 878  PGPLGPQG----EKGVMGYPGPPGVPGPIGPLGLPGHVGARGPP--------GSQGPKGQ 925

Query: 922  TKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAV 981
                    +  +        E   QG        G       +G   +   QG+      
Sbjct: 926  RGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGD 985

Query: 982  HGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANE 1041
             G+  E  ++G+  +V   G   +  ++G    +   G+  E  A G      + G   E
Sbjct: 986  RGLPGEPGLRGLQGDVGPPG---EMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGE 1042

Query: 1042 DAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1101
               +G        G+  +D ++G+      +G+  ED  +G      + G        G+
Sbjct: 1043 PGLRGEPGAPGEEGLQGKDGLKGVPG---GRGLPGEDGEKGEMGLPGIIGPLGRSGQTGL 1099

Query: 1102 AKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAA 1161
                   G+  +    G   +    G   EV  +G   +    G      A G    V  
Sbjct: 1100 PGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSG---PKGARGTRGAVGH 1156

Query: 1162 HGIANEDAAQGIAN------EDAAQGIAHEDAVQGIANEDAV-------HGVAKEVAAHG 1208
             G+   D   GI        +    G+      +G   ED+         G    V   G
Sbjct: 1157 LGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQG 1216

Query: 1209 VANEDAAHAIAKPDAARGIANEVAAQGIATE---DVADGIANEDAAHGVANEVAAHGISK 1265
               E  A          G+      QG   E       G+  E  + G   +  A G S 
Sbjct: 1217 ERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSG 1276

Query: 1266 EDAV---QGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVE 1322
            +  +   QG+      QG    D + G   +    G       QG+     I+G      
Sbjct: 1277 KPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPG------KQGLPG---IRGGPGRTG 1327

Query: 1323 VQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIAN 1382
            + G      V+G +    + GI      QG+  +   Q       AQG        G+  
Sbjct: 1328 LAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKG 1387

Query: 1383 EDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHG 1442
            +    G+      QG       +G A  V + G       +G        GI       G
Sbjct: 1388 QPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTG 1447

Query: 1443 IANEDAAQGIANEDAAQG 1460
               E   +G   E   QG
Sbjct: 1448 PRGE---KGFRGETGPQG 1462



 Score = 75.9 bits (185), Expect = 4e-13
 Identities = 154/913 (16%), Positives = 258/913 (28%), Gaps = 73/913 (7%)

Query: 1388 GIAKEDPVQGVANEDAVQGVANEVEVQG---VAHEDAVQGIANEDAAHGIANEVAAHGIA 1444
            G +   PV G   +  + G+     +QG   +     + G+  E    G A  + + G  
Sbjct: 540  GFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYP 599

Query: 1445 NEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAR 1504
                 QG+A  +   G        G   E    G   E    G+  +            +
Sbjct: 600  GR---QGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKG------RQ 650

Query: 1505 GIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEV 1564
            G   +   +G A  D + G+       G      + G    +   G+       G+    
Sbjct: 651  GFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIP---GPMGLSGNK 707

Query: 1565 TAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGI 1624
               G+  +   QG   E        ++ A      P              +  K    G 
Sbjct: 708  GLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPP-------------GMRGKSGPSGQ 754

Query: 1625 ANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAV 1684
                  QG +      G   +  + G    +  +G+       G      ++G   E+  
Sbjct: 755  TGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPG---PPGLKGTQGEEGP 811

Query: 1685 HGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNE 1744
             G   E+   G   +   +G A E   +G+  EV  QG   +    G        G+T  
Sbjct: 812  IGAFGELGPRGKPGQ---KGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGS 868

Query: 1745 VAAHGIANEDAAQGIAHEDAVQGIANEDAVHS------VAKEVAAHGVANEDAAHAIAKP 1798
            +   G        G   E  V G      V        +   V A G             
Sbjct: 869  IGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGS 928

Query: 1799 DAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGI 1858
                G+  E   QG   E    G        G        G   +  +QG+      +G+
Sbjct: 929  RGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGL 988

Query: 1859 AKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAA 1918
              E  ++G+  +V   G   E  ++G    +   G+  E  A+G      +     E   
Sbjct: 989  PGEPGLRGLQGDVGPPG---EMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGL 1045

Query: 1919 QGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANE 1978
            +G       +G+  +D  +G+      +G+  ED  +G        G        G+   
Sbjct: 1046 RGEPGAPGEEGLQGKDGLKGVP---GGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGP 1102

Query: 1979 DAAQGIAHEDAVQGIANEDAVHGVANEDAAHA----IAK--PDAARGIANEVAAQGIATE 2032
            +   GI  +    G   +    G   E  +      I K  P  ARG    V   G+   
Sbjct: 1103 EGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGP 1162

Query: 2033 DVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEA 2092
            D   GI       G   +     +  P    G   E          +     +G      
Sbjct: 1163 DGEPGIPGYRGHQG---QPGPSGLPGPKGEKGYPGEDSTV------LGPPGPRGEPGPVG 1213

Query: 2093 AQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVAN 2152
             Q    +  A G        G+      QG   E    G        G+  E  ++G   
Sbjct: 1214 DQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQG------EQGLKGERGSEGNKG 1267

Query: 2153 EVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQG 2212
            +  A G + +  + G+      QG+     IQG    D   G   ++   G       +G
Sbjct: 1268 KKGAPGPSGKPGIPGL------QGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRG 1321

Query: 2213 VANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDA 2272
                    G       +G +      G+      + +  +   QG      A G      
Sbjct: 1322 GPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCG 1381

Query: 2273 VHGIANEDAVYDI 2285
              G+  +   Y +
Sbjct: 1382 DPGLKGQPGEYGV 1394



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 174/1013 (17%), Positives = 282/1013 (27%), Gaps = 132/1013 (13%)

Query: 67   GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126
            G+  E  + G A  + + G        G        G      + G A ++  +G     
Sbjct: 579  GLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIP 638

Query: 127  AVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIA 186
             ++G       QG   +   +G A  D + G+       G      +           I 
Sbjct: 639  GIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIP 698

Query: 187  NEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQ 246
                  G+S    + GI  +   QG A E    G   +    G+     ++G +      
Sbjct: 699  GP---MGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGP---S 752

Query: 247  GVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 306
            G   +  +QG +      G   ++   G    +  +G+       G      ++G   E+
Sbjct: 753  GQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPG---PPGLKGTQGEE 809

Query: 307  AVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVA 366
               G   E+   G   +        P+   G+  EV  QG                 G  
Sbjct: 810  GPIGAFGELGPRGKPGQKGYAGEPGPE---GLKGEVGDQGNI---------------GKI 851

Query: 367  KEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAA 426
             E    G+  E  + G + E    G       +     P    G+       G+      
Sbjct: 852  GETGPVGLPGEVGMTGSIGEKGERG-------SPGPLGPQGEKGVMGYPGPPGVPGPIGP 904

Query: 427  QGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKE 486
             G+   V A G       +G        G+  E   QG   E   QG            +
Sbjct: 905  LGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQG------------K 952

Query: 487  VAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGV 546
               HG+  K            RG   +   QG+       G+  E  + G+  +V   G 
Sbjct: 953  RGPHGLIGKTGN------PGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPG- 1005

Query: 547  ANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAV 606
                                E+  +G    +   G+  E  A G        G   E  +
Sbjct: 1006 --------------------EMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGL 1045

Query: 607  QGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVA--NEDAAQAI 664
            +G        G+  +D  +G+       G+  ED  +G   E  L G++          +
Sbjct: 1046 RGEPGAPGEEGLQGKDGLKGVPG---GRGLPGEDGEKG---EMGLPGIIGPLGRSGQTGL 1099

Query: 665  AKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAA 724
              P+   GI  +    G   +    G   E  ++G   ++   G       +G       
Sbjct: 1100 PGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGL 1159

Query: 725  QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHE 784
             G   E  + G        G +      G+      +G   ED    V      +G    
Sbjct: 1160 MGPDGEPGIPGYRGHQGQPGPS------GLPGPKGEKGYPGEDST--VLGPPGPRGEPGP 1211

Query: 785  DAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGV 844
               QG   E  A G    V   G+      QG   E   QG   E  + G    +  +G 
Sbjct: 1212 VGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQG---EQGLKGERGSEGNKGK 1268

Query: 845  AKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIA-NEGVANEVAAQG 903
                   G      +QG++  + + G                A GI+ N G       QG
Sbjct: 1269 KGAPGPSGKPGIPGLQGLLGPKGIQGY-------------HGADGISGNPGKIGPPGKQG 1315

Query: 904  IATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAA 963
            +               GI        +A       +       G      + G+      
Sbjct: 1316 LP--------------GIRGGPGRTGLAGAPGPPGVKGSSGLPG------SPGIQGPKGE 1355

Query: 964  QGVANEVAAQGVANEDAV---HGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGI 1020
            QG+  +   QG           G   +  ++G   E  VQG+      QG        G 
Sbjct: 1356 QGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLT---GFQGFPGPKGPEGD 1412

Query: 1021 ANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG 1073
            A  V   G       +G       +GI       G   E   +G       +G
Sbjct: 1413 AGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRG 1465


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 86.7 bits (213), Expect = 3e-16
 Identities = 204/1095 (18%), Positives = 292/1095 (26%), Gaps = 88/1095 (8%)

Query: 968  NEVAAQGVANEDAVH----GVANEDAVQGVANEVE----VQGIAHKDAIQGIANEDAAHG 1019
            +E+     AN+D ++    G   E   +G    +E    ++G    +   G+       G
Sbjct: 428  SEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMG 487

Query: 1020 IANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDA 1079
               +V   G        G+   D   G    +    +       G A        A E  
Sbjct: 488  PTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLM--LPFRFGGGGDAGSKGPMVSAQESQ 545

Query: 1080 AQGIAHED--AVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGV 1137
            AQ I  +   A++G A    + G    V   G      ++G   +   QG        G 
Sbjct: 546  AQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGG---LKGEPGDVGPQGPRGVQGPPGP 602

Query: 1138 AHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAV 1197
            A +   +G A  D A G+  +    G    D   G+  E   +G        G   +D  
Sbjct: 603  AGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGE 662

Query: 1198 HGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANE 1257
             G   EV   G+  E     +  P    G        G+  +    G        G   +
Sbjct: 663  RGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQ 722

Query: 1258 VAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQG-IAKEDPVQGVANEDP--I 1314
                G       QG       +G   +  + G+   D   G   KE P      + P   
Sbjct: 723  QGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGP 782

Query: 1315 QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKE 1374
            QG       +GV   D ++G+       G                     ED   G   +
Sbjct: 783  QGPIGYPGPRGVKGADGIRGLKGTKGEKG---------------------EDGFPGFKGD 821

Query: 1375 DAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGI 1434
              ++G   E    G   ED  +G        G    +   G   +  V G+       G 
Sbjct: 822  MGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGP 881

Query: 1435 ANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAA 1494
               +   G    +  +G        G   +    G   E    G+  +    G +  D  
Sbjct: 882  KGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGP 941

Query: 1495 HAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIE 1554
               A P   RG        G        G   +D   G   +    G   +    G    
Sbjct: 942  ---AGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGV 998

Query: 1555 DAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHS 1614
               QG   E    G        G   E  L  +   E             G   +     
Sbjct: 999  VGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKE-------------GTKGDPGPAG 1045

Query: 1615 IANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDA 1674
            +  KD   G+      +G+   V A G+   +   G        G A     +G A    
Sbjct: 1046 LPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPG------PPGPAGSPGERGPAGAAG 1099

Query: 1675 VQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIAN 1734
              GI       G        G   E   QG A  D +QG        G+       G   
Sbjct: 1100 PIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPV------GLPGPAGPVGPPG 1153

Query: 1735 EDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHA 1794
            ED   G   E    G   +   QG       QG   +        E    G         
Sbjct: 1154 EDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKG 1213

Query: 1795 IAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDA 1854
               P    G    V  QG+       G P E    G   ++   G        G    D 
Sbjct: 1214 DEGPRGFPGPPGPVGLQGL------PGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADG 1267

Query: 1855 AQGIAKEDPIQGVANEVEVQGVAHEDAV------------QGIANEDAAHGIANEDAAQG 1902
             QG        G   E    G A E  +            +G   E    G A     +G
Sbjct: 1268 PQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKG 1327

Query: 1903 IANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVA 1962
               +D  +         G        G A QD   G   +D   G   +  + G   E  
Sbjct: 1328 PPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPG---QTGSPGPTGEPG 1384

Query: 1963 AHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIAN 2022
              G   +    G A  +  QG        G+       G      A     PD  RGI  
Sbjct: 1385 PSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPG 1444

Query: 2023 EVAAQGIATEDVADG 2037
             V  QG+      DG
Sbjct: 1445 PVGEQGLPGSPGPDG 1459



 Score = 75.9 bits (185), Expect = 4e-13
 Identities = 190/1062 (17%), Positives = 290/1062 (27%), Gaps = 85/1062 (8%)

Query: 1210 ANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAV 1269
            A E  A AI +  A   +       G+       G        G   +V   G       
Sbjct: 541  AQESQAQAILQ-QARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGP 599

Query: 1270 QGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHE 1329
             G A +   +G A  D  +G+  +   +G    D + G+  E   +G        G   +
Sbjct: 600  PGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGD 659

Query: 1330 DAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGI 1389
            D  +G   E    G+  E   +G+                G+  +   +G        G 
Sbjct: 660  DGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGP 719

Query: 1390 AKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAA 1449
              +    G       QG       +G   +  + G+   D   G   +    G   E   
Sbjct: 720  PGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGK---EGPPGEKGG 776

Query: 1450 QGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANE 1509
            QG       QG       +G+   D + G+       G   ED           +G   E
Sbjct: 777  QG---PPGPQGPIGYPGPRGVKGADGIRGLK---GTKGEKGEDGFPGFKGDMGIKGDRGE 830

Query: 1510 VATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGV 1569
            +   G   ED  +G       +G    +   G   ++ V G+      QG    +   G 
Sbjct: 831  IGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGF 890

Query: 1570 ANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDA 1629
               +  +G             +   +    P    G   E     I  K   +G +  D 
Sbjct: 891  PGANGEKGGRG-------TPGKPGPRGQRGPTGPRG---ERGPRGITGKPGPKGNSGGDG 940

Query: 1630 AQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAK 1689
              G   E   +G                 G        G   +D + G   +    G   
Sbjct: 941  PAGPPGERGPNG------------PQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQG 988

Query: 1690 EVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHG 1749
            +    G       QG   E    G        G   E  + G+A ++   G         
Sbjct: 989  KTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKG--------- 1039

Query: 1750 IANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVA 1809
               +    G+  +D   G+        +   V A G+   +       P    G A    
Sbjct: 1040 ---DPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEG------PPGPPGPAGSPG 1090

Query: 1810 AQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVAN 1869
             +G A      GIP      G        G   E   QG A  D  QG     P+ G+  
Sbjct: 1091 ERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQG-----PV-GLPG 1144

Query: 1870 EVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQG 1929
                 G   ED  +G   E    G   +   QG       Q    +    G   E   +G
Sbjct: 1145 PAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRG 1204

Query: 1930 IANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDA 1989
                        +  + G   ++  +G        G+      QG+      +G   +  
Sbjct: 1205 ------------QQGLFGQKGDEGPRGFPGPPGPVGL------QGLPGPPGEKGETGDVG 1246

Query: 1990 VQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVAN 2049
              G        G +    A     P    G    V  +G   E    G+  E    G   
Sbjct: 1247 QMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKG 1306

Query: 2050 EDAAQAIAKPDAAHGIAN-EGIATEDVADGIAEDA-VQGITNEEAAQAIAKQDAAHGITK 2107
            E   +  + P  A G    +G   +D   G        G          A QD   G   
Sbjct: 1307 ERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKG 1366

Query: 2108 EDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQG 2167
            +D   G T    + G   E    G   +    G A  +  QG   E  A+G A  +   G
Sbjct: 1367 DDGEPGQTG---SPGPTGEPGPSGPPGKRGPPGPAGPEGRQG---EKGAKGEAGLEGPPG 1420

Query: 2168 VANEVEVQGIAHK---DAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVAN 2224
                +  QG   K   D ++GI      QG+       G        G+       G   
Sbjct: 1421 KTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKG 1480

Query: 2225 EDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHG 2266
            E    G+   +   G   E   R +     + G   E    G
Sbjct: 1481 EKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITG 1522



 Score = 71.2 bits (173), Expect = 1e-11
 Identities = 196/1059 (18%), Positives = 277/1059 (26%), Gaps = 83/1059 (7%)

Query: 654  VVANEDAAQAIAK--------PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVA 705
            V A E  AQAI +        P    G+       G       +G   +   QG      
Sbjct: 539  VSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQG 598

Query: 706  AHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVAN 765
              G + +   +G A  D A+G+  +   +G    D + G+  E    G        G   
Sbjct: 599  PPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPG 658

Query: 766  EDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQG 825
            +D  +G   EV  +G+  E   +G+       G        GV   D   G       QG
Sbjct: 659  DDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPG---PPGPPGVTGMDGQPGPKGNVGPQG 715

Query: 826  VANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPD 885
               E    G      AQG+     A G   E   +G + +  L G+   +        P 
Sbjct: 716  ---EPGPPGQQGNPGAQGLPGPQGAIGPPGE---KGPLGKPGLPGMPGADG-------PP 762

Query: 886  AAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAA 945
               G   EG   E   QG         I      G+              A  I      
Sbjct: 763  GHPG--KEGPPGEKGGQG--PPGPQGPIGYPGPRGVK------------GADGIRGLKGT 806

Query: 946  QGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHK 1005
            +G   ED   G   +   +G   E+   G   ED   G        G    +   G   K
Sbjct: 807  KGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGK 866

Query: 1006 DAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGI 1065
              + G+       G    +   G    +  +G        G   +    G   E   +GI
Sbjct: 867  LGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGI 926

Query: 1066 ANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAV 1125
              +   +G +  D   G   E    G        G        G        G   E   
Sbjct: 927  TGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGF 986

Query: 1126 QGVANE------VEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAA 1179
            QG          V  QG   E    G        G   E    G+A ++  +G   +   
Sbjct: 987  QGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKG---DPGP 1043

Query: 1180 QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATE 1239
             G+  +D   G+       G+   V A G+   +       P    G A     +G A  
Sbjct: 1044 AGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEG------PPGPPGPAGSPGERGPAGA 1097

Query: 1240 DVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGI 1299
                GI       G        G   E   QG A  D  QG        G+       G 
Sbjct: 1098 AGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPV------GLPGPAGPVGP 1151

Query: 1300 AKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAA 1359
              ED  +G   E   +G   +   QG       QG   +    G   E   +G       
Sbjct: 1152 PGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRG------- 1204

Query: 1360 QDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHE 1419
                     QG+  +   +G        G      + G   E    G   ++   G    
Sbjct: 1205 --------QQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGP 1256

Query: 1420 DAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIA---HEDAVQGIANEDAV 1476
                G    D   G    +   G   E    G A E    G          +G   E   
Sbjct: 1257 RGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGP 1316

Query: 1477 HGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANE 1536
             G A      G   +D       P    G        G A +D   G   +D   G    
Sbjct: 1317 SGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGS 1376

Query: 1537 VAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQA 1596
                G        G        G        G   E  ++G   +            A  
Sbjct: 1377 PGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTG----PIGPQGAPG 1432

Query: 1597 IAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDA 1656
               PD   GI   V    +       G        G+       G   E    G+     
Sbjct: 1433 KPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIG 1492

Query: 1657 AQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHG 1695
              G   E   +G+       G   E  + G +  +   G
Sbjct: 1493 PPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPG 1531



 Score = 69.7 bits (169), Expect = 3e-11
 Identities = 197/1070 (18%), Positives = 288/1070 (26%), Gaps = 100/1070 (9%)

Query: 692  ANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAA 751
            A E  AQ I  + A   +       G+       G      ++G   +    G       
Sbjct: 541  AQESQAQAILQQ-ARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGP 599

Query: 752  HGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANE 811
             G A +   +G A  D  +G+  +   +G    D + G+  E    G        G   +
Sbjct: 600  PGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGD 659

Query: 812  DAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGV 871
            D  +G   E   +G+  E    G+       G        G+  +   +G V  +   G 
Sbjct: 660  DGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGP 719

Query: 872  VANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGI-AKDAAHGITKEEAAQAI 930
               +    A   P     I   G    +   G+     ADG        G   E+  Q  
Sbjct: 720  PGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQG- 778

Query: 931  AKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAV 990
                           QG        GV   D  +G+      +G   ED   G   +  +
Sbjct: 779  -----------PPGPQGPIGYPGPRGVKGADGIRGLKG---TKGEKGEDGFPGFKGDMGI 824

Query: 991  QGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANE 1050
            +G   E+   G   +D  +G       +G    +   G   +    G+      QG    
Sbjct: 825  KGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGS 884

Query: 1051 VAAHGISKEDAVQG---------IANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1101
            +   G    +  +G            +    G   E   +GI  +   +G +  D   G 
Sbjct: 885  IGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGP 944

Query: 1102 AKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAA 1161
              E   +G        G        G        G   E   QG        G+   V  
Sbjct: 945  PGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGV---VGP 1001

Query: 1162 HGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKP 1221
             G   E    G        G   E  + G+A ++   G   +    G+  +D    +   
Sbjct: 1002 QGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKG---DPGPAGLPGKDGPPGLRGF 1058

Query: 1222 DAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGI 1281
               RG+   V A G+   +   G      + G      A G        GI      QG 
Sbjct: 1059 PGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPI------GIPGRPGPQGP 1112

Query: 1282 AKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAA 1341
                  +G   E   QG A  D +QG      + G A  V   G   ED  +G   E   
Sbjct: 1113 PGPAGEKGAPGEKGPQGPAGRDGLQGPVG---LPGPAGPVGPPG---EDGDKGEIGEPGQ 1166

Query: 1342 HGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANE 1401
             G   +   QG       Q    +    G   E   +G       QG+  +   +G    
Sbjct: 1167 KGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRG------QQGLFGQ---KGDEGP 1217

Query: 1402 DAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGI 1461
                G    V +QG+       G   E    G   ++   G        G    D  QG 
Sbjct: 1218 RGFPGPPGPVGLQGLP------GPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQG- 1270

Query: 1462 AHEDAVQGIANEDAV--HGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATED 1519
                   GI N  AV   G   E    G+  E        P   RG   E    G A   
Sbjct: 1271 ----PPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPG---PKGERGEKGESGPSGAAGPP 1323

Query: 1520 VADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVV 1579
               G   +D   G    V   G        G A +D   G            +D   G  
Sbjct: 1324 GPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGD---------KGDDGEPGQT 1374

Query: 1580 NEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAA 1639
                                     G   E        K    G A  +  QG       
Sbjct: 1375 GSP----------------------GPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGE 1412

Query: 1640 HGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANE 1699
             G+       G      A G    D  +GI      QG+       G    +   G+   
Sbjct: 1413 AGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGL 1472

Query: 1700 DPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHG 1749
                G   E    G+   +   G   E   +G+     + G   E    G
Sbjct: 1473 KGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITG 1522



 Score = 62.4 bits (150), Expect = 5e-09
 Identities = 178/1027 (17%), Positives = 268/1027 (26%), Gaps = 89/1027 (8%)

Query: 67   GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126
            G      ++G   +V  QG        G A +    G A  D A+G+  +   +G    D
Sbjct: 574  GPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFD 633

Query: 127  AVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIA 186
             + G+  E   +G        G   +D   G   E   +G+  E   + +          
Sbjct: 634  GLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPP 693

Query: 187  NEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQ 246
                  G+  +   +G        G   +    G       QG       +G   +  + 
Sbjct: 694  GPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLP 753

Query: 247  GVAHEDAVQGIANEDAAHGITN---------EVAAHGIANEDAAQGIANEDAAQGIAHED 297
            G+   D   G   ++   G             +   G      A GI      +G   ED
Sbjct: 754  GMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGED 813

Query: 298  AVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIA 357
               G   +  + G   E+   G   ED       P+   G        G        G  
Sbjct: 814  GFPGFKGDMGIKGDRGEIGPPGPRGEDG------PEGPKGRGGPNGDPGPL------GPP 861

Query: 358  NEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAA 417
             E    GV       G       +G +      G    +       KP    G   +   
Sbjct: 862  GEKGKLGVP---GLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKP----GPRGQRGP 914

Query: 418  HGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANE 477
             G   E   +GI  +    G S  D   G   E    G        G        G   +
Sbjct: 915  TGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNG---PQGPTGFPGPKGPPGPPGK 971

Query: 478  DAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGV 537
            D + G   +    G   K            +G   E    G        G   E  + G+
Sbjct: 972  DGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGL 1031

Query: 538  ANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAV 597
            A +    G   +     +   D   G+      +G+     A G+   +   G       
Sbjct: 1032 AGK---EGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPP----- 1083

Query: 598  HGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVAN 657
             G A     +G A      G+      QG        G   E   QG    D L G V  
Sbjct: 1084 -GPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGL 1142

Query: 658  EDAAQAIAKP--DAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAV 715
               A  +  P  D   G   E    G   +   QG       QG   +    G   E   
Sbjct: 1143 PGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGP 1202

Query: 716  QGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANE 775
            +G                QG+  +    G        G      + G   E    G   +
Sbjct: 1203 RG---------------QQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQ 1247

Query: 776  VEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGV 835
            +   G        G    D   G    +   G   E    G A E    G        G 
Sbjct: 1248 MGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGE 1307

Query: 836  ANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGV 895
              E    G +      G       +G   ++   G      +   +  P         G 
Sbjct: 1308 RGEKGESGPS------GAAGPPGPKGPPGDDGPKG------SPGPVGFPGDPGPPGEPGP 1355

Query: 896  ANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAH 955
            A +    G   +D   G  +  + G T E        +         +  QG   E  A 
Sbjct: 1356 AGQDGPPGDKGDDGEPG--QTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQG---EKGAK 1410

Query: 956  GVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANED 1015
            G A  +   G    +  QG        G    D ++G+   V  QG      + G    D
Sbjct: 1411 GEAGLEGPPGKTGPIGPQGAP------GKPGPDGLRGIPGPVGEQG------LPGSPGPD 1458

Query: 1016 AAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIA 1075
               G        G+  +   +G   E    G+   +   G   E   +G+     + G  
Sbjct: 1459 GPPGPMGPPGLPGLKGDSGPKG---EKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPK 1515

Query: 1076 NEDAAQG 1082
             E    G
Sbjct: 1516 GEQGITG 1522


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 84.7 bits (208), Expect = 1e-15
 Identities = 193/1085 (17%), Positives = 287/1085 (26%), Gaps = 100/1085 (9%)

Query: 112  GVANEVAAQGVANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANED 171
            G A    +QG   E   +G       QG+  E  V G        G  +     G++   
Sbjct: 132  GPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPF 191

Query: 172  AAQDIAKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVA 231
            +AQ          +A  D   G+  +  +        + G       QG+  +    G  
Sbjct: 192  SAQ----------MAGLDEKSGLGSQVGLM-----PGSVGPVGPRGPQGLQGQQGGAGPT 236

Query: 232  NEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQ 291
                  G    +   G    +   G   ED   G        G A    A+G        
Sbjct: 237  GPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLP 296

Query: 292  GIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATED 351
            G+      +G      + G   EV A G   E      A P    G    +  +G+  E 
Sbjct: 297  GL------KGHRGHKGLEGPKGEVGAPGSKGE------AGPTGPMGAMGPLGPRGMPGER 344

Query: 352  VADGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGI 411
               G        G      AHG+  +    G +      G   N                
Sbjct: 345  GRLGPQGAPGQRG------AHGMPGKPGPMGPLGIPGSSGFPGNP--------------- 383

Query: 412  ANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAV 471
                            G+  E    G    +  QG   E    G        G    D  
Sbjct: 384  ----------------GMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGT 427

Query: 472  QGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANE 531
             G        G +    + G            P   RG   +    G   E    G   E
Sbjct: 428  PGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEA---GPKGE 484

Query: 532  DAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGV 591
               HG+   +   G   +             G   E    G      +DG+     A G 
Sbjct: 485  PGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGE 544

Query: 592  ANEVAVHGVAIEDAVQGVANEDAV---HGVANEDAAQGIAKEVTAHGVANEDAVQGVVNE 648
               V   G        G   E  +    G+      QG   ++   G   ED   G    
Sbjct: 545  RGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGS 604

Query: 649  DALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHG 708
              + G    +  +  +  P  + G   +    G A     +G   +D   G +  V   G
Sbjct: 605  IGIRG----QPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPG 660

Query: 709  ISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE---VAAHGVANEDPVQGVAN 765
            ++ E   QG       QG+       G   +    GV  +   V   G   E    G   
Sbjct: 661  LAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERG 720

Query: 766  EDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQG 825
            E  + G+  E  + G    D  +G        G        G+  E    G       +G
Sbjct: 721  EPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRG 780

Query: 826  VANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPD 885
               E    G A  D A+G+   +   G       +G      L G             P 
Sbjct: 781  GIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVG------------PPG 828

Query: 886  AAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAA 945
            +     + G      A G A     DG       G+ K E  +   K DA          
Sbjct: 829  SRGNPGSRGENGPTGAVGFAGPQGPDG-----QPGV-KGEPGEPGQKGDAG-----SPGP 877

Query: 946  QGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHK 1005
            QG+A     HG       +G        G        G        G        G   K
Sbjct: 878  QGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGK 937

Query: 1006 DAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGI 1065
            +   G+  +  +HG   +    G       +G   ED   G        G + +  + G+
Sbjct: 938  EGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGM 997

Query: 1066 ANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAV 1125
              +   +G+       G   +    G   +    G      ++G   E   +G A  D  
Sbjct: 998  PGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGT 1057

Query: 1126 QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHE 1185
             G    V  +G   +    G+     A G    V A G A +    G        G A +
Sbjct: 1058 PGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGK 1117

Query: 1186 DAVQG 1190
              + G
Sbjct: 1118 RGLPG 1122



 Score = 82.8 bits (203), Expect = 4e-15
 Identities = 201/1131 (17%), Positives = 298/1131 (26%), Gaps = 51/1131 (4%)

Query: 1118 GVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANED 1177
            G A     QG   E   +G       QGI  E    G        G  +     G++   
Sbjct: 132  GPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPF 191

Query: 1178 AAQGIAHEDAVQGIANE-DAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGI 1236
            +AQ +A  D   G+ ++   + G    V   G          A P    G   +    G 
Sbjct: 192  SAQ-MAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGP 250

Query: 1237 ATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAA 1296
                   G    +   G   E    G +      G A    A+G      + G+      
Sbjct: 251  I------GSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGH 304

Query: 1297 QGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANE 1356
            +G+       G        G    +   G      + G        G   +  A G+  +
Sbjct: 305  KGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGK 364

Query: 1357 DAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGV 1416
                       + G      ++G A    A+G   E P QG   E    G      + G 
Sbjct: 365  PGPMGPLGIPGSSGFPGNPGMKGEAGPTGARG--PEGP-QGQRGETGPPGPVGSPGLPGA 421

Query: 1417 AHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAV 1476
               D   G      + G +    + G       QG       +G   +  V G   E   
Sbjct: 422  IGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGP 481

Query: 1477 HGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANE 1536
             G   E   HG+               RG    V   G   E  A G      + G+   
Sbjct: 482  KG---EPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGP 538

Query: 1537 VAAQGIANEVAVHGVAIEDAVQGVVKEVT---AHGVANEDAVQGVVNEDALHSVVA-NED 1592
              AQG    V   G        G   E     A G+     VQG   E  L  + A  ED
Sbjct: 539  KGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGP--EGKLGPLGAPGED 596

Query: 1593 AAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIA 1652
                   P  + GI  +  +  +     + G   +    G A      G   +D   G +
Sbjct: 597  GRPG---PPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPS 653

Query: 1653 NEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQ 1712
                  G+A E   QG       QG+       G   +    GV  +    G       +
Sbjct: 654  GPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGER 713

Query: 1713 GVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANED 1772
            G   E    G+      +G+A      G        G   +    G+      QG+  E 
Sbjct: 714  GNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGL------QGMPGER 767

Query: 1773 AVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVA 1832
             +          G   E  A   A  D ARG+   +   G A      G P      G  
Sbjct: 768  GIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPP 827

Query: 1833 NEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAH 1892
                  G   E+   G       QG   +  ++G   E   +G A     QG+A     H
Sbjct: 828  GSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPH 887

Query: 1893 GIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANED 1952
            G       +G               + G        G        G   ++   G+  + 
Sbjct: 888  GPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDP 947

Query: 1953 AAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIA 2012
             + G   +    G       +G   ED   G        G   +  + G+  +     + 
Sbjct: 948  GSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMP 1007

Query: 2013 KPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIAT 2072
                  G   +V   G   +    G      ++G   E   +  A         N+G   
Sbjct: 1008 GLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPA--------GNDGTPG 1059

Query: 2073 EDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGV 2132
             D A G   D                     G+     A G    V A G A +    G 
Sbjct: 1060 RDGAVGERGD--------------RGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGS 1105

Query: 2133 ANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAA 2192
               +   G A +    G       +G   +   +G        G+       G   E  +
Sbjct: 1106 RGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGS 1165

Query: 2193 QGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANE 2243
             G+       G        G        G       +G   E    G   E
Sbjct: 1166 AGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGE 1216



 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 169/952 (17%), Positives = 262/952 (27%), Gaps = 49/952 (5%)

Query: 1306 QGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANE 1365
            QG   E   +G       QG+  E  V G        G  +     G++   +AQ +A  
Sbjct: 140  QGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQ-MAGL 198

Query: 1366 DAAQGISKEDAVQ----GIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDA 1421
            D   G+  +  +     G       QG+  +    G        G    +   G    + 
Sbjct: 199  DEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEG 258

Query: 1422 VQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAK 1481
              G   ED   G        G A    A+G        G+      +G      + G   
Sbjct: 259  PPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGL------KGHRGHKGLEGPKG 312

Query: 1482 EVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVA---DGIANEDAAHGVANEVA 1538
            EV A G   E      A P    G    +  +G+  E       G   +  AHG+  +  
Sbjct: 313  EVGAPGSKGE------AGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPG 366

Query: 1539 AQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIA 1598
              G    + + G +      G+  E    G    +  QG   E      V +     AI 
Sbjct: 367  PMG---PLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIG 423

Query: 1599 KPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQ 1658
              D   G      +   +    + G       QG        G   +  V G   E   +
Sbjct: 424  T-DGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPK 482

Query: 1659 GIANEDAAQGIAH---EDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVA 1715
            G       QG      E+  +G   +    G    V   G       +G    D + G  
Sbjct: 483  GEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGN---RGFPGSDGLPGPK 539

Query: 1716 NEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVH 1775
                 +G       +G   +    G      A G+      QG   +    G   ED   
Sbjct: 540  GAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRP 599

Query: 1776 SVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEV 1835
                 +   G+  +  +  +  P  + G   +    G A      G P +D   G +  V
Sbjct: 600  GPPGSI---GIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPV 656

Query: 1836 AAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIA 1895
               G++ E   QG       QG+       G   +   QGV  +    G        G  
Sbjct: 657  GPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNP 716

Query: 1896 NEDAAQGIANEDAAQDIAN---EDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANED 1952
             E    GI      + +A     D  +G        G       QG+  E  + G     
Sbjct: 717  GERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPK 776

Query: 1953 AAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIA 2012
              +G   E  A G A  D A+G+       G A     +G      + G           
Sbjct: 777  GDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSR 836

Query: 2013 KPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIAT 2072
              +   G       QG   +    G   E    G A     Q +A     HG        
Sbjct: 837  GENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHG-------- 888

Query: 2073 EDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGV 2132
                +G+    ++G    +          + G        G        G   ++   G+
Sbjct: 889  ---PNGVP--GLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGL 943

Query: 2133 ANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAA 2192
              +  +HG   +    G       +G   ED   G        G   +  I G+  +   
Sbjct: 944  RGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGE 1003

Query: 2193 QGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANED 2244
            +G+       G   +    G   +    G      + G   E    G A  D
Sbjct: 1004 RGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGND 1055



 Score = 79.3 bits (194), Expect = 4e-14
 Identities = 142/797 (17%), Positives = 215/797 (26%), Gaps = 41/797 (5%)

Query: 65   AHGITNEDAVQGVANEVAAQGVANEDAAHGVANE------VAAHGVANEDAAQGVANEVA 118
            A G      + G    +  QG   +  AHG+  +      +   G +      G+  E  
Sbjct: 331  AMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAG 390

Query: 119  AQGVANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAK 178
              G    +  QG   E    G      + G    D   G      + G +    +     
Sbjct: 391  PTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPG 450

Query: 179  EDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQG 238
                Q        +G   +  V G   E   +G      +QG       +G        G
Sbjct: 451  SPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPG 510

Query: 239  VANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDA 298
                    G       +G    D   G        G       +G   +    G      
Sbjct: 511  TVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPG 570

Query: 299  VQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIAN 358
             +G+     V G   ++   G   ED       P  + GI  +  + G+     + G   
Sbjct: 571  ARGLTGNPGVQGPEGKLGPLGAPGEDGRPG---PPGSIGIRGQPGSMGLPGPKGSSGDPG 627

Query: 359  EDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAH 418
            +    G A      G   +D   G        G +A E   Q    P    G+       
Sbjct: 628  KPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPG-LAGERGEQGPPGPTGFQGLPGPPGPP 686

Query: 419  GIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANED 478
            G   +   QG+  +  A G       +G   E    GI      +G+A      G     
Sbjct: 687  GEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSP 746

Query: 479  AVHGVAKEVAAHGVANKDAAHAIA---KPDAARGIANEVAAQGIATEDVADGIANEDAVH 535
               G   +    G+        IA    P   RG   E  A+G A  D A G+       
Sbjct: 747  GPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPP 806

Query: 536  GVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEV 595
            G A      G   E     +  P  + G                 G   E+   G     
Sbjct: 807  GPAGPTGEKG---EPGPRGLVGPPGSRG---------------NPGSRGENGPTGAVGFA 848

Query: 596  AVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVV 655
               G   +  V+G   E    G A     QG+A     HG      ++G        G  
Sbjct: 849  GPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGAT 908

Query: 656  ANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAV 715
                +A  +  P  A G        G   ++   G+  +  + G   +    G       
Sbjct: 909  GFPGSAGRVGPPGPA-GAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGD 967

Query: 716  QGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANE 775
            +G   ED   G    D   G A      G+       G+  +   +G+       G   +
Sbjct: 968  KGDPGEDGQPG---PDGPPGPAGTTGQRGIV------GMPGQRGERGMPGLPGPAGTPGK 1018

Query: 776  VEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGV 835
            V   G   +    G      ++G   E    G A  D   G       +G   +    G+
Sbjct: 1019 VGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGL 1078

Query: 836  ANEDAAQGVAKEVTAHG 852
                 A G    V A G
Sbjct: 1079 PGSQGAPGTPGPVGAPG 1095



 Score = 78.6 bits (192), Expect = 7e-14
 Identities = 169/976 (17%), Positives = 249/976 (25%), Gaps = 19/976 (1%)

Query: 581  GIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANED 640
            G A    + G   E    G       QG+  E  V G        G        G++   
Sbjct: 132  GPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPF 191

Query: 641  AVQ--GVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQ 698
            + Q  G+  +  L   V     +     P    G+  +    G        G        
Sbjct: 192  SAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPI 251

Query: 699  GIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANED 758
            G        G   ED   G        G A     +G      + G+       G+    
Sbjct: 252  GSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPK 311

Query: 759  PVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVA 818
               G        G    +   G      + G        G   +  AHG+  +    G  
Sbjct: 312  GEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPL 371

Query: 819  NEDAAQGVANEDAVHGVANEDAA------QGVAKEVTAHGVTNEDAVQGVVNEEALHGVV 872
                + G      + G A    A      QG   E    G      + G +  +   G  
Sbjct: 372  GIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAK 431

Query: 873  ANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAK 932
                +      P +A    + G       QGI  +    G+      G   E   +    
Sbjct: 432  GPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVP-----GFKGEAGPKG--- 483

Query: 933  QDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQG 992
            +   H I       G   +    G        G   E  A G        G+      QG
Sbjct: 484  EPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQG 543

Query: 993  VANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVA 1052
                V   G        G   E    G        G+   +   G        G      
Sbjct: 544  ERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPG 603

Query: 1053 AHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVAN 1112
            + GI  +    G+     + G   +    G A     +G   +D   G +  V   G+A 
Sbjct: 604  SIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAG 663

Query: 1113 EDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQG 1172
            E   QG       QG+       G   +   QG+  +  A G        G   E    G
Sbjct: 664  ERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPG 723

Query: 1173 IANEDAAQGIA---HEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIAN 1229
            I      +G+A     D  +G        G        G+  E        P   RG   
Sbjct: 724  ITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIG 783

Query: 1230 EVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQG 1289
            E  A+G A  D A G+       G A      G      + G        G   E+   G
Sbjct: 784  EKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTG 843

Query: 1290 IANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDA 1349
                   QG   +  V+G   E   +G A     QG+A      G        G      
Sbjct: 844  AVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQG 903

Query: 1350 AQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVAN 1409
              G      +          G        G   ++   G+  +    G   +    G   
Sbjct: 904  PPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPG 963

Query: 1410 EVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQG 1469
                +G   ED   G        G   +    G+  +   +G+       G   +    G
Sbjct: 964  GPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTG 1023

Query: 1470 IANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDA 1529
               +    G      ++G   E      A  D   G    V  +G   +    G+     
Sbjct: 1024 ATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQG 1083

Query: 1530 AHGVANEVAAQGIANE 1545
            A G    V A G A +
Sbjct: 1084 APGTPGPVGAPGDAGQ 1099



 Score = 71.2 bits (173), Expect = 1e-11
 Identities = 123/669 (18%), Positives = 175/669 (26%), Gaps = 44/669 (6%)

Query: 1605 GIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANED 1664
            G   +  AH +  K    G      + G        G+  E    G    +  QG   E 
Sbjct: 351  GAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNP---GMKGEAGPTGARGPEGPQGQRGET 407

Query: 1665 AAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVA 1724
               G      + G    D   G      + G +      G       QG      ++G  
Sbjct: 408  GPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQP 467

Query: 1725 HEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAH 1784
             +  V G   E    G   E   HGI       G   +   +G            E  A 
Sbjct: 468  GDPGVPGFKGEAGPKG---EPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAP 524

Query: 1785 GVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKED 1844
            G      +  +  P  A+G    V + G        G P E    G      A G++   
Sbjct: 525  GNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPG------ARGLTGNP 578

Query: 1845 AVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIA 1904
             VQG   +    G   ED   G    + ++G   +    G+     + G   +    G A
Sbjct: 579  GVQGPEGKLGPLGAPGEDGRPGPPGSIGIRG---QPGSMGLPGPKGSSGDPGKPGEAGNA 635

Query: 1905 NEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAH 1964
                 +    +D   G S      G+A +   QG       QG+       G   +    
Sbjct: 636  GVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQ 695

Query: 1965 GIANEDAAQGIAN---EDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIA 2021
            G+  +  A G      E    G   E  + G+  E  + G    D       P    G  
Sbjct: 696  GVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDT 755

Query: 2022 NEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANE----------GIA 2071
                 QG+  E    G        G   E  A+  A  D A G+             G  
Sbjct: 756  GPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEK 815

Query: 2072 TEDVADGIA-------------EDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEV 2118
             E    G+              E+   G       Q    Q    G   E   +G     
Sbjct: 816  GEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSP 875

Query: 2119 AAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIA 2178
              QG+A     HG        G        G      + G        G        G  
Sbjct: 876  GPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEP 935

Query: 2179 HKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVH 2238
             K+   G+  +  + G    V   G A      G   +    G    D   G A      
Sbjct: 936  GKEGPPGLRGDPGSHG---RVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQR 992

Query: 2239 GVANEDAAR 2247
            G+      R
Sbjct: 993  GIVGMPGQR 1001



 Score = 62.8 bits (151), Expect = 4e-09
 Identities = 131/686 (19%), Positives = 190/686 (27%), Gaps = 54/686 (7%)

Query: 1616 ANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAV 1675
            A    +QG   +   +G        GI  E  V G        G  +     G++   + 
Sbjct: 134  AGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSA 193

Query: 1676 QGIANEDAVHGVAKEVAA-------------HGVANEDPVQGVANEDAVQGVANEVEVQG 1722
            Q +A  D   G+  +V                G+  +    G        G    +   G
Sbjct: 194  Q-MAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIG 252

Query: 1723 VAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANE---DAVHSVAK 1779
                +   G   ED   G        G A    A+G      + G+        +     
Sbjct: 253  SRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKG 312

Query: 1780 EVAAHGVANE---DAAHAIAKPDAARGIANE---VAAQGIATEDVADGIPNEDAAHGVAN 1833
            EV A G   E           P   RG+  E   +  QG   +  A G+P +    G   
Sbjct: 313  EVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLG 372

Query: 1834 EVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHG 1893
               + G      ++G A    A+G   E P QG   E    G      + G    D   G
Sbjct: 373  IPGSSGFPGNPGMKGEAGPTGARG--PEGP-QGQRGETGPPGPVGSPGLPGAIGTDGTPG 429

Query: 1894 IANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDA 1953
                  + G +    +         QG +     QGI  Q    G      V G   E  
Sbjct: 430  AKGPTGSPGTSGPPGSAGPPGSPGPQGST---GPQGIRGQPGDPG------VPGFKGEAG 480

Query: 1954 AQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAK 2013
             +G   E   HGI       G   +   +G        G   E    G      +  +  
Sbjct: 481  PKG---EPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPG 537

Query: 2014 PDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATE 2073
            P  A+G    V + G        G   E    G         +  P+   G    G   E
Sbjct: 538  PKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPL--GAPGE 595

Query: 2074 DVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVA 2133
            D   G       GI  +  +  +     + G   +    G       +G   +D   G +
Sbjct: 596  DGRPGPPGSI--GIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPS 653

Query: 2134 NEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAI---------- 2183
              V   G+A E   QG       QG+       G   +   QG+                
Sbjct: 654  GPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGER 713

Query: 2184 --QGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVA 2241
               G   E    G+  E    G    D  +G        G       QG+  E  + G  
Sbjct: 714  GNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTP 773

Query: 2242 NEDAARHMAKEDAAQGIANEDAAHGI 2267
                 R    E  A+G A  D A G+
Sbjct: 774  GPKGDRGGIGEKGAEGTAGNDGARGL 799



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 117/654 (17%), Positives = 174/654 (26%), Gaps = 45/654 (6%)

Query: 1623 GIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 1682
            G A    A+G        G+      +G+       G        G        G     
Sbjct: 279  GFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPR 338

Query: 1683 AVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIT 1742
             + G    +   G   +    G+  +    G        G      ++G A    A G  
Sbjct: 339  GMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPE 398

Query: 1743 NEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAAR 1802
                  G   E    G      + G    D          + G +    +   A P  + 
Sbjct: 399  GPQGQRG---ETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGS---AGPPGSP 452

Query: 1803 GIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKED 1862
            G       QGI  +    G+P      G   E   HGI       G   E+  +G   + 
Sbjct: 453  GPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPG---EEGKRGPRGDP 509

Query: 1863 PIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGIS 1922
               G    V  +G        G        G   E    G +    +Q         G+ 
Sbjct: 510  GTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLP 569

Query: 1923 KEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQ 1982
                 +G+      QG   +    G   ED   G    +   GI  +  + G+     + 
Sbjct: 570  ---GARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSI---GIRGQPGSMGLPGPKGSS 623

Query: 1983 GIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANED 2042
            G   +    G A      G   +D     + P    G+A E   QG        G+    
Sbjct: 624  GDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPP 683

Query: 2043 AAHGVANEDAAQAI-AKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQDA 2101
               G   +   Q +   P A   +   G        G  E  + G+  E+        D 
Sbjct: 684  GPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERG--EPGITGLPGEKGMAGGHGPDG 741

Query: 2102 AHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVAN 2161
              G        G T     QG+  E    G+A      G       +G   E  A+G A 
Sbjct: 742  PKGSPGPSGTPGDTGPPGLQGMPGE---RGIA------GTPGPKGDRGGIGEKGAEGTAG 792

Query: 2162 EDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQG 2221
             D  +G+   +   G A     +G   E   +G+     + G        G    V   G
Sbjct: 793  NDGARGLPGPLGPPGPAGPTGEKG---EPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAG 849

Query: 2222 VANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVHG 2275
                D   GV  E                 E   +G A      G+A     HG
Sbjct: 850  PQGPDGQPGVKGEPG---------------EPGQKGDAGSPGPQGLAGSPGPHG 888



 Score = 60.1 bits (144), Expect = 3e-08
 Identities = 141/778 (18%), Positives = 208/778 (26%), Gaps = 71/778 (9%)

Query: 75   QGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANE 134
            +G    V   G   E  A G      + G+     AQG    V + G        G   E
Sbjct: 506  RGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGE 565

Query: 135  DAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQGI 194
              + G        G+   +   G        G      +  I  +  +  +     + G 
Sbjct: 566  PGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGD 625

Query: 195  SKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAV 254
              +    G A     +G   +D   G +      G+A E   QG       QG+      
Sbjct: 626  PGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGP 685

Query: 255  QGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE 314
             G   +    G+  +  A G       +G   E    GI      +G+A      G    
Sbjct: 686  PGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGS 745

Query: 315  VAAHGVANEDAAHAIAKPDAAHGIANEVATQGI---ATEDVADGIANEDAAHGVAKEVTA 371
                G   +     +       GIA     +G      E  A+G A  D A G+   +  
Sbjct: 746  PGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGP 805

Query: 372  HGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIAN 431
             G A     +G             E   + +  P  + G      + G      A G A 
Sbjct: 806  PGPAGPTGEKG-------------EPGPRGLVGPPGSRG---NPGSRGENGPTGAVGFAG 849

Query: 432  EVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHG 491
                         QG   +   +G   E   +G A     QG+A     HG       +G
Sbjct: 850  P------------QGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHG------PNG 891

Query: 492  VANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIA------NEDAVHGVANEVAAHG 545
            V           P  A G        G      A G A       ++   G+  +  +HG
Sbjct: 892  VPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHG 951

Query: 546  VANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDA 605
               +             G A      G   +   DG    D   G A      G+     
Sbjct: 952  RVGD------------RGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIV---- 995

Query: 606  VQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIA 665
              G+  +    G+       G   +V   G   +    G V     +G V  E   +  A
Sbjct: 996  --GMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPV-GEPGPEGPA 1052

Query: 666  KPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQ 725
              D   G    V   G   +    G+     A G    V A G + +    G        
Sbjct: 1053 GNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPP 1112

Query: 726  GIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHED 785
            G A +  + G        G   +   HG   +   +G      +QG+       G   E 
Sbjct: 1113 GRAGKRGLPG------PQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNG---EQ 1163

Query: 786  AVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQG 843
               GI       G    V   G        G       +G   E    G   E    G
Sbjct: 1164 GSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPG 1221



 Score = 56.6 bits (135), Expect = 3e-07
 Identities = 107/558 (19%), Positives = 149/558 (26%), Gaps = 22/558 (3%)

Query: 57   IANEDADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANE 116
            +    A    G    D + G       +G        G   +    G      A+G+   
Sbjct: 518  VGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGN 577

Query: 117  VAAQGVANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDI 176
               QG   +    G   ED   G      ++G   +  + G+     + G   +      
Sbjct: 578  PGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRG---QPGSMGLPGPKGSSGDPGKPGEAGN 634

Query: 177  AKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAV 236
            A     +    +D   G S      G+A E   QG       QG+       G   +   
Sbjct: 635  AGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGD 694

Query: 237  QGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIA---NEDAAQGIANEDAAQGI 293
            QGV  +    G       +G   E    GIT      G+A     D  +G        G 
Sbjct: 695  QGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGD 754

Query: 294  AHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVA 353
                 +QG+  E  + G        G   E  A   A  D A G+   +   G A     
Sbjct: 755  TGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPA----- 809

Query: 354  DGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIAN 413
             G   E    G    V   G       +G   E+   G V          +P    G   
Sbjct: 810  -GPTGEKGEPGPRGLVGPPGSRGNPGSRG---ENGPTGAVGFAGPQGPDGQP-GVKGEPG 864

Query: 414  EVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQG 473
            E    G A     QG+A     HG    + V G+      QG        G A      G
Sbjct: 865  EPGQKGDAGSPGPQGLAGSPGPHG---PNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPG 921

Query: 474  IANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDA 533
             A      G   E    G                RG A      G   +   DG    D 
Sbjct: 922  PAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDG 981

Query: 534  VHGVANEVAAHGVA---NEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHG 590
              G A      G+     +     +       G   +V   G   +    G      ++G
Sbjct: 982  PPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNG 1041

Query: 591  VANEVAVHGVAIEDAVQG 608
               E    G A  D   G
Sbjct: 1042 PVGEPGPEGPAGNDGTPG 1059



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 87/474 (18%), Positives = 126/474 (26%), Gaps = 16/474 (3%)

Query: 56   DIANEDADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVAN 115
            +  N       G   +D   G +  V   G+A E    G        G+       G   
Sbjct: 631  EAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGG 690

Query: 116  EVAAQGVANEDAV---QGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDA 172
            +   QGV  +       G   E    G   E  + G+  E    G    D  +G      
Sbjct: 691  KPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSG 750

Query: 173  AQDIAKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVAN 232
                      Q +  E    G       +G   E  A+G A  D  +G+       G A 
Sbjct: 751  TPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAG 810

Query: 233  EDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQG 292
                +G      + G        G   E+   G        G   +   +G   E   +G
Sbjct: 811  PTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKG 870

Query: 293  IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDV 352
             A     QG+A     HG       +GV           P  A G        G      
Sbjct: 871  DAGSPGPQGLAGSPGPHG------PNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAG 924

Query: 353  ADGIA------NEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPD 406
            A G A       ++   G+  +  +HG   +    G        G    ED       P 
Sbjct: 925  APGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKG-DPGEDGQPGPDGPP 983

Query: 407  AAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIA 466
               G   +    G+  +   +G+       G   +    G   +    G      + G  
Sbjct: 984  GPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPV 1043

Query: 467  HEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIA 520
             E   +G A  D   G    V   G         +     A G    V A G A
Sbjct: 1044 GEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDA 1097



 Score = 35.8 bits (81), Expect = 0.52
 Identities = 59/315 (18%), Positives = 85/315 (26%), Gaps = 9/315 (2%)

Query: 63   DAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGV 122
            D A G+       G A     +G        G        G   E+   G       QG 
Sbjct: 794  DGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGP 853

Query: 123  ANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAA 182
              +  V+G   E   +G A     QG+A     HG        G+      +       A
Sbjct: 854  DGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHG------PNGVPGLKGGRGTQGPPGA 907

Query: 183  QDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANE 242
                      G        G A      G  KE P  G+  +    G   +    G    
Sbjct: 908  TGFPGSAGRVGPPGPAGAPGPAGPLGEPG--KEGP-PGLRGDPGSHGRVGDRGPAGPPGG 964

Query: 243  VEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGI 302
               +G   ED   G        G T +    G+  +   +G+       G   +    G 
Sbjct: 965  PGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGA 1024

Query: 303  ANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAA 362
              +    G      ++G   E      A  D   G    V  +G   +    G+     A
Sbjct: 1025 TGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGA 1084

Query: 363  HGVAKEVTAHGVANE 377
             G    V A G A +
Sbjct: 1085 PGTPGPVGAPGDAGQ 1099


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score = 83.2 bits (204), Expect = 3e-15
 Identities = 163/918 (17%), Positives = 243/918 (26%), Gaps = 49/918 (5%)

Query: 1118 GVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANED 1177
            G+       G+     ++G    +  QG       HG    V   G    D A+G+  + 
Sbjct: 485  GLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDT 544

Query: 1178 AAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIA 1237
              +G    D + G+  E    G    V   G   ED       P    G A E   +G+ 
Sbjct: 545  GPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLL 604

Query: 1238 TEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQ 1297
                + G        G+     A G        G   +    G       QG+      +
Sbjct: 605  GPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEK 664

Query: 1298 GIAKEDPVQGVANED-PI-----QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQ 1351
            G      + G+   D P+     +G   E   QG        G        G +     Q
Sbjct: 665  GPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQ 724

Query: 1352 GIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEV 1411
            G   E        ED   G   +  ++G   +  A G   ED  +G   +    G     
Sbjct: 725  GEKGE------KGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPP 778

Query: 1412 EVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIA 1471
               G   +  V G+       G    +   G       +G + +    G+  E    G  
Sbjct: 779  GSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSR 838

Query: 1472 NEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAH 1531
             E    G   +    G   +D A  I      +G+       G        G   +D   
Sbjct: 839  GERGQPGATGQPGPKGDVGQDGAPGI---PGEKGLPGLQGPPGFPGPKGPPGHQGKDGRP 895

Query: 1532 GVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANE 1591
            G   +    G   +    G A     QG   EV   G        G   E  L  +   E
Sbjct: 896  GHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGRE 955

Query: 1592 DAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGI 1651
             A   +  P    G                 G       +G        G +     +G 
Sbjct: 956  GAKGELGPPGPL-GKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGP 1014

Query: 1652 ANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAV 1711
                   G+  +  ++G       +G   E    G   +    G        G A     
Sbjct: 1015 LGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGE 1074

Query: 1712 QGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANE 1771
            +G   +V   G       +G A      GI       G    D AQG      + G   +
Sbjct: 1075 EGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGD 1134

Query: 1772 DAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGV 1831
            D V          GV        +  P   +G   +V + G                HG 
Sbjct: 1135 DGVRGFV------GVIGPPGLQGLPGPPGEKGEVGDVGSMG---------------PHGA 1173

Query: 1832 ANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAA 1891
                   G +  +   G+       G   E   +G A +    G        GI      
Sbjct: 1174 PGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPG------APGIPGPKGD 1227

Query: 1892 HGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANE 1951
             G   +    G A     +    ED A+G      + G        G   +  V GI   
Sbjct: 1228 IGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPG------DLGPPGDPGVSGIDGS 1281

Query: 1952 DAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAI 2011
               +G   +V   G        G       +G +     +G   E    G    D     
Sbjct: 1282 PGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGR 1341

Query: 2012 AKPDAARGIANEVAAQGI 2029
              P  ARG    V  +G+
Sbjct: 1342 TGPMGARGPPGRVGPEGL 1359



 Score = 82.4 bits (202), Expect = 5e-15
 Identities = 158/903 (17%), Positives = 242/903 (26%), Gaps = 41/903 (4%)

Query: 667  PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG 726
            P    G+       G+      +G    +  QG       HG        G    D A+G
Sbjct: 480  PPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARG 539

Query: 727  IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDA 786
            +  +   +G    D + G+  E    G        G   ED  +G        G A E  
Sbjct: 540  LPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPG 599

Query: 787  VQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAK 846
             +G+     + G        G+     A+G        G   +   HG       QG+  
Sbjct: 600  PRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIG 659

Query: 847  EVTAHGVTNEDAVQGVVNEEALHGVVANE--DAAQAIAKPDAAHGIAN----EGVANEVA 900
                 G      + G+   +   G   +E     +    P  + G        GV     
Sbjct: 660  TPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSG 719

Query: 901  AQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANE 960
             +G+  E    G  +D   G   +   +    +  A     ED  +G   +    G    
Sbjct: 720  NRGLQGEKGEKG--EDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGP 777

Query: 961  DAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGI 1020
              + G   ++   G+       G        G    +  +G + K    G+  E    G 
Sbjct: 778  PGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGS 837

Query: 1021 ANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAA 1080
              E    G   +   +G   +D A GI  E    G+       G       QG   +D  
Sbjct: 838  RGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQG---KDGR 894

Query: 1081 QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHE 1140
             G   +    G   +    G A  +   G   E    G        G   E  + G+   
Sbjct: 895  PGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGR 954

Query: 1141 DAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1200
            +  +G        G        G        G       +G        G        G 
Sbjct: 955  EGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGP 1014

Query: 1201 AKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATED---------VADGIANEDAA 1251
                   G+  +  +     P   +G   E    G   +D            G A     
Sbjct: 1015 LGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGE 1074

Query: 1252 HGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANE 1311
             G   +V A G       +G A      GI       G    D AQG      + G   +
Sbjct: 1075 EGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGD 1134

Query: 1312 DPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGI 1371
            D ++G        GV     +QG+       G   +  + G                QG 
Sbjct: 1135 DGVRGFV------GVIGPPGLQGLPGPPGEKGEVGDVGSMG------PHGAPGPRGPQGP 1182

Query: 1372 SKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAA 1431
            +  +   G+       G   E   +G A +    G        G+       G   +   
Sbjct: 1183 TGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPG------APGIPGPKGDIGEKGDSGP 1236

Query: 1432 HGIANEVAAHGIANEDAAQGIANEDAAQ---GIAHEDAVQGIANEDAVHGVAKEVAAHGV 1488
             G A      G   ED A+G           G   +  V GI       G   +V   G 
Sbjct: 1237 SGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGP 1296

Query: 1489 ANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAV 1548
                       P   RG +  +  +G   E  A G    D   G    + A+G    V  
Sbjct: 1297 PGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGP 1356

Query: 1549 HGV 1551
             G+
Sbjct: 1357 EGL 1359



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 172/968 (17%), Positives = 260/968 (26%), Gaps = 57/968 (5%)

Query: 1289 GIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANED 1348
            G+  E+ A+G      +QG        G    V   G    D  +G+  +    G    D
Sbjct: 500  GLKGEEGAEGPQGPRGLQGP------HGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFD 553

Query: 1349 AAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVA 1408
               G+  E   +         G   ED  +G        G A E   +G+       G  
Sbjct: 554  GLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPT 613

Query: 1409 NEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQ 1468
                V G+      +G        G   +   HG       QG+      +G      + 
Sbjct: 614  GRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIP 673

Query: 1469 GIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANED 1528
            G+   D   G        G          A P    G      T G        G   ED
Sbjct: 674  GLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGED 733

Query: 1529 AAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNE------D 1582
               G   +V  +G   +    G   ED  +G   +    G A E+   G   E       
Sbjct: 734  GFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQA---GQAGEEGPPGSAGEKGKLGVP 790

Query: 1583 ALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGI 1642
             L           +I  P    G    +     + K    G+  +    G   E    G 
Sbjct: 791  GLPGYPGRPGPKGSIGFP----GPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGA 846

Query: 1643 SKEDAVQGIANEDAAQGIANEDAAQGIAHEDAV------QGIANEDAVHGVAKEVAAHGV 1696
            + +   +G   +D A GI  E    G+             G   +D   G   +    G 
Sbjct: 847  TGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGF 906

Query: 1697 ANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAA 1756
              +    G A     QG   EV   G        G   E    G+     A G       
Sbjct: 907  QGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGP 966

Query: 1757 QGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATE 1816
             G      ++G                 G                RG        G+  +
Sbjct: 967  LGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQ 1026

Query: 1817 DVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGV 1876
              ++G        G   E    G + +D + G        G A     +G   +V   G 
Sbjct: 1027 SGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGH 1086

Query: 1877 AHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAA 1936
                  +G A      GI       G    D AQ         G   +D V+G       
Sbjct: 1087 KGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFV----- 1141

Query: 1937 QGIAKEDAVQGIANEDAAQGIANEVAA---HGIANEDAAQGIANEDAAQGIAHEDAVQGI 1993
             G+     +QG+      +G   +V +   HG       QG    +   G+       G 
Sbjct: 1142 -GVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGA 1200

Query: 1994 ANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAA 2053
              E    G A +        P  A GI       G   +    G A      G   ED A
Sbjct: 1201 VGEKGERGDAGDPG------PPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGA 1254

Query: 2054 QAIAKPDAAHG----IANEGIATEDVADG-------IAEDAVQGITNEEAAQAIAKQDAA 2102
            +    P    G      + G++  D + G       +      G + E  A     +   
Sbjct: 1255 KGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGP 1314

Query: 2103 HGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANE 2162
             G    +  +G   E  A+G    D   G    + A G       +G+       G   E
Sbjct: 1315 SGHMGREGREG---EKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLR---GIPGPVGE 1368

Query: 2163 DAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGV 2222
              + G   ++   G      + G+  +   +G    +   G+       G   +    GV
Sbjct: 1369 PGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGV 1428

Query: 2223 ANEDAAQG 2230
                  +G
Sbjct: 1429 QGPPGPKG 1436



 Score = 79.3 bits (194), Expect = 4e-14
 Identities = 181/997 (18%), Positives = 264/997 (26%), Gaps = 73/997 (7%)

Query: 939  ITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVE 998
            +T      G+       G    +  QG        G        G    D  +G+  +  
Sbjct: 486  LTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTG 545

Query: 999  VQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISK 1058
             +G    D + G+  E    G    V   G   ED  +G        G A E    G+  
Sbjct: 546  PKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLG 605

Query: 1059 EDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQG 1118
                 G        GI     A+G        G   +   HG        G+      +G
Sbjct: 606  PRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKG 665

Query: 1119 VANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDA 1178
                  + G+       G       +G   E  A G        G       +G +    
Sbjct: 666  PPGNPGIPGLPGS---DGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRG 722

Query: 1179 AQ---GIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQG 1235
             Q   G   ED   G   +  + G   +  A G   ED       P    G A E    G
Sbjct: 723  LQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEG---PKGQAGQAGEEGPPG 779

Query: 1236 IATEDVADGI------------ANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAK 1283
             A E    G+                   G    +   G S +    G+  E    G   
Sbjct: 780  SAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRG 839

Query: 1284 EDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHG 1343
            E    G   +   +G   +D   G+  E  + G+       G       QG   +D   G
Sbjct: 840  ERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQG---KDGRPG 896

Query: 1344 IANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDA 1403
               +    G   +      A     QG + E    G        G   E   QG+   + 
Sbjct: 897  HPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGE---QGLPGLEG 953

Query: 1404 VQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQ---- 1459
             +G   E+   G   ++   G+       G   +    G+  +    G    + +     
Sbjct: 954  REGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERG 1013

Query: 1460 --------GIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVA 1511
                    G+  +   +G        G   E    G   +D       P    G A    
Sbjct: 1014 PLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSG 1073

Query: 1512 TQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVAN 1571
             +G   +  A G        G A      GI       G    D  QG        G   
Sbjct: 1074 EEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKG 1133

Query: 1572 EDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAA---HSIANKDAAQGIANQD 1628
            +D V+G V        V      Q +  P    G   +V +   H        QG    +
Sbjct: 1134 DDGVRGFVG-------VIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSE 1186

Query: 1629 AAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVA 1688
               G+   V   G   E   +G A +    G      A GI       G   +    G A
Sbjct: 1187 GTPGLPGGVGQPGAVGEKGERGDAGDPGPPG------APGIPGPKGDIGEKGDSGPSGAA 1240

Query: 1689 KEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAH 1748
                  G   ED  +G      + G        G   +  V GI       G   +V   
Sbjct: 1241 GPPGKKGPPGEDGAKGSVGPTGLPGDL------GPPGDPGVSGIDGSPGEKGDPGDVGGP 1294

Query: 1749 GIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEV 1808
            G        G       +G +          E  A G    D       P  ARG    V
Sbjct: 1295 GPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRV 1354

Query: 1809 AAQGIATEDVADGIP---NEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQ 1865
              +G+       GIP    E    G   ++   G      + G+  +   +G   E    
Sbjct: 1355 GPEGLR------GIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKG---EKGHI 1405

Query: 1866 GVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQG 1902
            G+   +   G A E   QG+       G   +    G
Sbjct: 1406 GLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPG 1442



 Score = 78.6 bits (192), Expect = 7e-14
 Identities = 185/1021 (18%), Positives = 274/1021 (26%), Gaps = 56/1021 (5%)

Query: 67   GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126
            G+     ++G       QG       HG    V   G    D A+G+  +   +G    D
Sbjct: 494  GLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFD 553

Query: 127  AVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIA 186
             + G+  E   +G        G   ED   G        G A E   + +     +    
Sbjct: 554  GLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPT 613

Query: 187  NEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQ 246
                  GI      +G        G   +    G       QG+      +G      + 
Sbjct: 614  GRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIP 673

Query: 247  GVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 306
            G+   D   G    +   G T E  A G        G       +G +    +QG   E 
Sbjct: 674  GLPGSDGPLGHPGHE---GPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEK 730

Query: 307  AVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVA 366
               G        G+  +        P    G        G A E+   G A E    GV 
Sbjct: 731  GEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVP 790

Query: 367  KEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAA 426
                  G       +G +      G +  +  +    +P    G+  E    G   E   
Sbjct: 791  ---GLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQP----GLEGERGPPGSRGERGQ 843

Query: 427  QGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKE 486
             G   +    G   +D   GI  E    G+       G       QG        G   E
Sbjct: 844  PGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGE 903

Query: 487  VAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGV 546
            +   G         +  P   +G   EV   G        G   E  + G+     A G 
Sbjct: 904  LGFQGQTGPPGPAGVLGP---QGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGE 960

Query: 547  ANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAV 606
                       P    G        G        G        G    V  +G   E   
Sbjct: 961  LGPPGPLGKEGPAGLRGFPGPKGGPG------DPGPTGLKGDKGPPGPVGANGSPGERGP 1014

Query: 607  QGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAK 666
             G A    + G +  +   G A +  + G   E    G   +D + G +       A A 
Sbjct: 1015 LGPAGGIGLPGQSGSEGPVGPAGKKGSRG---ERGPPGPTGKDGIPGPLGPLGPPGA-AG 1070

Query: 667  PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG 726
            P    G   +V A G       +G A      GI    A H         G    D AQG
Sbjct: 1071 PSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGP-AGH--------PGPPGADGAQG 1121

Query: 727  IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDA 786
                  + G   +D V G    +   G+     + G   E    G    +   G      
Sbjct: 1122 RRGPPGLFGQKGDDGVRGFVGVIGPPGLQG---LPGPPGEKGEVGDVGSMGPHGAPGPRG 1178

Query: 787  VQGIANEDAAHGIANEVAAHGVANEDAAQGVANE---DAAQGVANEDAVHGVANEDAAQG 843
             QG    +   G+   V   G   E   +G A +     A G+       G   +    G
Sbjct: 1179 PQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSG 1238

Query: 844  VAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANE-GVANEVAAQ 902
             A      G   ED  +G V    L G +        ++  D + G   + G        
Sbjct: 1239 AAGPPGKKGPPGEDGAKGSVGPTGLPGDL-GPPGDPGVSGIDGSPGEKGDPGDVGGPGPP 1297

Query: 903  GIATEDVADG-IAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANED 961
            G + E  A G   K    G    E  +             E  A+G    D   G     
Sbjct: 1298 GASGEPGAPGPPGKRGPSGHMGREGRE------------GEKGAKGEPGPDGPPGRTGPM 1345

Query: 962  AAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIA 1021
             A+G    V  +G+     + G   E  + G   ++   G      + G+  +    G  
Sbjct: 1346 GARGPPGRVGPEGLR---GIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEK 1402

Query: 1022 NEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQ 1081
              +   G+       G   +    G+       G        G        G+A     +
Sbjct: 1403 GHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQK 1462

Query: 1082 G 1082
            G
Sbjct: 1463 G 1463



 Score = 75.1 bits (183), Expect = 8e-13
 Identities = 155/835 (18%), Positives = 217/835 (25%), Gaps = 51/835 (6%)

Query: 63   DAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGV 122
            D   G+  E   +G    V   G   ED   G        G A E   +G+     + G 
Sbjct: 553  DGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGP 612

Query: 123  ANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAA 182
                 V G+      +G        G   +   HG       QG+      +        
Sbjct: 613  TGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGI 672

Query: 183  QDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANE 242
              +   D   G       +G   E  AQG        G      V+G +    +QG    
Sbjct: 673  PGLPGSDGPLG---HPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQG---- 725

Query: 243  VEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGI 302
               +G   ED   G   +    G   +  A G   ED  +G   +    G A E+   G 
Sbjct: 726  --EKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQ---AGQAGEEGPPGS 780

Query: 303  ANED---AVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANE 359
            A E     V G+       G            P    G + +    G+  E    G   E
Sbjct: 781  AGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGE 840

Query: 360  DAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVA--------------NEDAAQAIAKP 405
                G   +    G   +D   G+  E  L G+                 +D        
Sbjct: 841  RGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQ 900

Query: 406  DAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGI 465
                G   +    G A     QG   EV   G        G   E    G+   + A+G 
Sbjct: 901  RGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGE 960

Query: 466  AHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVA 525
                   G      + G        G            P    G       +G       
Sbjct: 961  LGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGG 1020

Query: 526  DGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANE 585
             G+  +    G        G   E         D   G    +   G A     +G   +
Sbjct: 1021 IGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGD 1080

Query: 586  DAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGV 645
              A G        G A      G+       G    D AQG        G   +D V+G 
Sbjct: 1081 VGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGF 1140

Query: 646  VNEDALHGVVANEDAAQAIAKPDAAHGIANEVAA---HGIANEDAAQGIANEDAAQGIAN 702
            V        V      Q +  P    G   +V +   HG       QG    +   G+  
Sbjct: 1141 VG-------VIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPG 1193

Query: 703  EVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQG 762
             V   G   E   +G A +    G        GI       G   +    G A     +G
Sbjct: 1194 GVGQPGAVGEKGERGDAGDPGPPG------APGIPGPKGDIGEKGDSGPSGAAGPPGKKG 1247

Query: 763  VANEDVVQGVANEVEVQ---GIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVAN 819
               ED  +G      +    G   +  V GI       G   +V   G        G   
Sbjct: 1248 PPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPG 1307

Query: 820  EDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGV---VNEEALHGV 871
                +G +      G   E  A+G        G T     +G    V  E L G+
Sbjct: 1308 PPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGI 1362



 Score = 68.6 bits (166), Expect = 7e-11
 Identities = 149/840 (17%), Positives = 219/840 (26%), Gaps = 52/840 (6%)

Query: 1397 GVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANED 1456
            G+       G+     ++G    +  QG       HG    V   G    D A+G+  + 
Sbjct: 485  GLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDT 544

Query: 1457 AAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIA 1516
              +G    D + G+  E    G    V   G   ED       P    G A E   +G+ 
Sbjct: 545  GPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLL 604

Query: 1517 TEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQ 1576
                + G        G+     A+G    V   G       QG       HG       Q
Sbjct: 605  GPRGSPGPTGRPGVTGIDGAPGAKG---NVGPPGEPGPPGQQG------NHGSQGLPGPQ 655

Query: 1577 GVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANE 1636
            G++                    P    GI     +         +G   +  AQG    
Sbjct: 656  GLIGTPGEKG-------------PPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGS 702

Query: 1637 VAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGV 1696
                G      V+G +     QG   E        ED   G   +  + G   +  A G 
Sbjct: 703  AGPPGYPGPRGVKGTSGNRGLQGEKGEKG------EDGFPGFKGDVGLKGDQGKPGAPGP 756

Query: 1697 ANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAA 1756
              ED  +G   +    G        G   +  V G+       G    +   G       
Sbjct: 757  RGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGE 816

Query: 1757 QGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATE 1816
            +G + +    G+  E        E    G   +         D A GI  E    G+   
Sbjct: 817  KGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGP 876

Query: 1817 DVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGV 1876
                G P      G   +    G   +    G   +    G A     QG   EV   G 
Sbjct: 877  P---GFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGE 933

Query: 1877 AHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAA 1936
                   G   E    G+   + A+G                +G        G       
Sbjct: 934  RGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGL 993

Query: 1937 QGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANE 1996
            +G        G       +G        G+  +  ++G       +G   E    G   +
Sbjct: 994  KGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGK 1053

Query: 1997 DAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAI 2056
            D + G          A P    G   +V A G        G A      G+         
Sbjct: 1054 DGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGP 1113

Query: 2057 AKPDAAHGIANE-GIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVT 2115
               D A G     G+  +   DG+      G+      Q         G+      +G  
Sbjct: 1114 PGADGAQGRRGPPGLFGQKGDDGVR--GFVGVIGPPGLQ---------GLPGPPGEKGEV 1162

Query: 2116 NEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVE-- 2173
             +V + G       HG        G    +   G+   V   G   E   +G A +    
Sbjct: 1163 GDVGSMG------PHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPP 1216

Query: 2174 -VQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVA 2232
               GI       G   +    G A      G   ED A+G        G        GV+
Sbjct: 1217 GAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVS 1276



 Score = 63.2 bits (152), Expect = 3e-09
 Identities = 137/750 (18%), Positives = 208/750 (27%), Gaps = 47/750 (6%)

Query: 1523 GIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNED 1582
            G    D A G+  +   +G      + G+  E   +G    V   G   ED  +G     
Sbjct: 530  GRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPP 589

Query: 1583 ALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGI 1642
               +  A E   + +  P  + G         I     A+G        G   +   HG 
Sbjct: 590  G-PTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGS 648

Query: 1643 SKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPV 1702
                  QG+      +G        G+   D   G    +   G   E  A G       
Sbjct: 649  QGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTG---EKGAQGPPGSAGP 705

Query: 1703 QGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHE 1762
             G      V+G +    +QG       +G   ED   G   +V   G   +  A G   E
Sbjct: 706  PGYPGPRGVKGTSGNRGLQGE------KGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGE 759

Query: 1763 DAVQGI------ANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANE---VAAQGI 1813
            D  +G       A E+     A E    GV           P  + G       +  +G 
Sbjct: 760  DGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGK 819

Query: 1814 ATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEV 1873
            + +    G+  E    G   E    G + +   +G   +D A GI  E  + G+      
Sbjct: 820  SGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGF 879

Query: 1874 QGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQ 1933
             G       QG   +D   G   +    G   +      A     QG + E    G    
Sbjct: 880  PGPKGPPGHQG---KDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGP 936

Query: 1934 DAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGI 1993
                G   E  + G+   + A+G        G       +G        G      ++G 
Sbjct: 937  PGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGD 996

Query: 1994 ANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAA 2053
                   G            P    G+  +  ++G        G   E    G   +D  
Sbjct: 997  KGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGI 1056

Query: 2054 QAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEA-----AQAIAKQDAAH-GITK 2107
                 P    G A       D  D +     +G   ++       Q   +  A H G   
Sbjct: 1057 PGPLGPLGPPGAAGPSGEEGDKGD-VGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPG 1115

Query: 2108 EDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVA------------ 2155
             D AQG        G   +D   G    +   G+       G   EV             
Sbjct: 1116 ADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPG 1175

Query: 2156 ---AQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDA---AQGVANEVAAHGVANEDA 2209
                QG    +   G+   V   G   +   +G A +     A G+       G   +  
Sbjct: 1176 PRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSG 1235

Query: 2210 AQGVANEVAAQGVANEDAAQGVANEVAVHG 2239
              G A     +G   ED A+G      + G
Sbjct: 1236 PSGAAGPPGKKGPPGEDGAKGSVGPTGLPG 1265



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 73/389 (18%), Positives = 108/389 (27%), Gaps = 5/389 (1%)

Query: 1884 GIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKED 1943
            G+       G+      +G    +  Q         G        G    D A+G+  + 
Sbjct: 485  GLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDT 544

Query: 1944 AVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVA 2003
              +G    D   G+  E    G        G   ED  +G        G A E    G+ 
Sbjct: 545  GPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLL 604

Query: 2004 NEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQA-IAKPDAA 2062
                +          GI     A+G        G   +   HG       Q  I  P   
Sbjct: 605  GPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEK 664

Query: 2063 HGIANEGIATEDVADG-IAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQ 2121
                N GI     +DG +     +G T E+ AQ         G       +G +     Q
Sbjct: 665  GPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQ 724

Query: 2122 ---GVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIA 2178
               G   ED   G   +V   G   +  A G   E   +G   +    G        G  
Sbjct: 725  GEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEK 784

Query: 2179 HKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVH 2238
             K  + G+       G    +   G       +G + +    G+  E    G   E    
Sbjct: 785  GKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQP 844

Query: 2239 GVANEDAARHMAKEDAAQGIANEDAAHGI 2267
            G   +   +    +D A GI  E    G+
Sbjct: 845  GATGQPGPKGDVGQDGAPGIPGEKGLPGL 873



 Score = 35.8 bits (81), Expect = 0.52
 Identities = 30/163 (18%), Positives = 45/163 (27%)

Query: 2113 GVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEV 2172
            G+T      G+       G        G        G    V   G    D  +G+  + 
Sbjct: 485  GLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDT 544

Query: 2173 EVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVA 2232
              +G    D + G+  E   +G    V   G   ED  +G        G A E   +G+ 
Sbjct: 545  GPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLL 604

Query: 2233 NEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVHG 2275
                  G         +     A+G        G   +   HG
Sbjct: 605  GPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHG 647


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 81.3 bits (199), Expect = 1e-14
 Identities = 187/919 (20%), Positives = 250/919 (27%), Gaps = 59/919 (6%)

Query: 1370 GISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANED 1429
            G + +D   G       +G+     ++G A      G+       G   E    G     
Sbjct: 225  GPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLK 284

Query: 1430 AAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVA 1489
              +G+  E  A G      A G        G A      G    D   G        G  
Sbjct: 285  GENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFP 344

Query: 1490 NEDAAHAIAKP------DAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIA 1543
                A     P      + A G   E   QG A      G    + + G   E+   GI 
Sbjct: 345  GSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIP 404

Query: 1544 NEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAA 1603
                + G        G        G A E    G   E         E     I     A
Sbjct: 405  GAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRG----ERGEAGIPGVPGA 460

Query: 1604 HGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANE 1663
             G   +  +      +   G A +  A G       +GI  E   +G A E  A G A  
Sbjct: 461  KGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGE---KGPAGERGAPGPAGP 517

Query: 1664 DAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGV 1723
              A G    D V G      + G      + G       QG +      G +      GV
Sbjct: 518  RGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGV 577

Query: 1724 AHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAA 1783
                   G    D A G   E    G        G   E   QG            +   
Sbjct: 578  M---GFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGP 634

Query: 1784 HGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKE 1843
             G            P    G   E   +G A    A G P      G   E    G++  
Sbjct: 635  PGPQGLQGLPGTGGPPGENGKPGEPGPKGDAG---APGAPGGKGDAGAPGERGPPGLAGA 691

Query: 1844 DAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGI 1903
              ++G A     +G       +G A      G A    +QG+  E    G       +G 
Sbjct: 692  PGLRGGAGPPGPEGG------KGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGE 745

Query: 1904 ANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAA 1963
                 A  +  +D  +G +      G A Q   +G      + GIA    + G   E   
Sbjct: 746  PGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGP 805

Query: 1964 HGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANE 2023
             G A    A G   E   +G   E    G   E    GVA        A P   +G+  E
Sbjct: 806  PGPAGFPGAPGQNGEPGGKG---ERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGE 862

Query: 2024 VAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDA 2083
              + G        G A    A G+     +     P    G   +        DG    A
Sbjct: 863  RGSPG------GPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGK--------DGPPGPA 908

Query: 2084 VQGITNEEAAQAIA--KQDAAH-GITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHG 2140
              G T    +  ++  K DA   G      AQG        G+A    A G+A      G
Sbjct: 909  --GNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPG 966

Query: 2141 VANEDAAQGVANE---VAAQGVANE---------DAVQGVANEVEVQGIAHKDAIQGIAN 2188
                   QGV  E     A G++ E           + G A E    G    D + G   
Sbjct: 967  PRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDG 1026

Query: 2189 EDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARH 2248
                +G   E  + G        G    V   G + +    G A      G A    A  
Sbjct: 1027 SPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPG 1086

Query: 2249 MAKEDAAQGIANEDAAHGI 2267
                   +G   E  A GI
Sbjct: 1087 PQGPRGDKGETGERGAAGI 1105



 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 199/1002 (19%), Positives = 259/1002 (25%), Gaps = 59/1002 (5%)

Query: 1190 GIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANE- 1248
            G A      G    +   G A +D           RG+      +G A      G+    
Sbjct: 207  GQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHR 266

Query: 1249 --DAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQ 1306
              D  +G   E  A G+  E+   G+  E+ A G        G        G A      
Sbjct: 267  GFDGRNGEKGETGAPGLKGEN---GLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGND 323

Query: 1307 GVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANED 1366
            G    D   G        G A      G   E    G    + A G   E   Q  A   
Sbjct: 324  GARGSDGQPGPPGP---PGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQ 380

Query: 1367 AAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIA 1426
               G    +   G   E    GI     + G        G      ++G A E    G  
Sbjct: 381  GPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAK 440

Query: 1427 NEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAH 1486
             E    G   E    GI     A+G   +D + G    + + G A E    G       +
Sbjct: 441  GEPGPRGERGEA---GIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPN 497

Query: 1487 GVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEV 1546
            G+  E        P   RG       +G A E   DG+       G+       G   + 
Sbjct: 498  GIPGEKG------PAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKP 551

Query: 1547 AVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGI 1606
               G   E    G        G        G    D        E        P    G 
Sbjct: 552  GPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGK-NGERGGPGGPGPQGPPGK 610

Query: 1607 ANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAA 1666
              E             G        G        G        G   E   +G A    A
Sbjct: 611  NGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGA 670

Query: 1667 QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHE 1726
             G    DA  G   E    G+A      G A      G    +  +G A      G A  
Sbjct: 671  PG-GKGDA--GAPGERGPPGLAGAPGLRGGA------GPPGPEGGKGAAGPPGPPGAAGT 721

Query: 1727 DAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGV 1786
              +QG+  E    G        G      A G+  +D  +G          A +    G 
Sbjct: 722  PGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGE 781

Query: 1787 ANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAV 1846
                    IA P  + G   E    G A      G P ++   G   E  A G   E   
Sbjct: 782  GGAPGLPGIAGPRGSPGERGETGPPGPAG---FPGAPGQNGEPGGKGERGAPGEKGEGGP 838

Query: 1847 QGIANEDAAQGIAKEDPIQGVANEVEVQG---VAHEDAVQGIANEDAAHGIANEDAAQGI 1903
             G+A      G A     QGV  E    G    A     +G+     ++G        G 
Sbjct: 839  PGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGS 898

Query: 1904 ANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAA 1963
              +D     A    A G       +G A Q   +G               AQG       
Sbjct: 899  PGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKG------------SPGAQGPPGAPGP 946

Query: 1964 HGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANE 2023
             GIA    A+G+A      G       QG+  E    G            P    G+A  
Sbjct: 947  LGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGT 1006

Query: 2024 VAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDA 2083
                G      +DG+   D + G   +        P A     + G        G    A
Sbjct: 1007 AGEPGRDGNPGSDGLPGRDGSPGGKGDRGENG--SPGAPGAPGHPG------PPGPVGPA 1058

Query: 2084 VQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVAN 2143
              G + +      A    A G      A G       +G   E  A G+       G   
Sbjct: 1059 --GKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGH---RGFPG 1113

Query: 2144 EDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQG 2185
               A G       QG        G    V   G   KD   G
Sbjct: 1114 NPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSG 1155



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 201/1041 (19%), Positives = 280/1041 (26%), Gaps = 73/1041 (7%)

Query: 1073 GIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEV 1132
            G A +D   G       +G+     + G A      G+     ++G    D   G   E 
Sbjct: 225  GPAGKDGESGRPGRPGERGLPGPPGIKGPA------GIPGFPGMKGHRGFDGRNGEKGET 278

Query: 1133 EVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIA 1192
               G+  E+ + G       +G    +   G   E    G+     A+G        G  
Sbjct: 279  GAPGLKGENGLPG------ENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQP 332

Query: 1193 NEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAH 1252
                  G A    + G   E         + A G   E   QG A      G    + + 
Sbjct: 333  GPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSP 392

Query: 1253 GVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANED 1312
            G   E+   GI     + G        G      ++G A E    G   E   +G   E 
Sbjct: 393  GGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEA 452

Query: 1313 PIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGIS 1372
             I GV       G   ED   G   E  A+G+       G A E  A          GI 
Sbjct: 453  GIPGVP------GAKGEDGKDGSPGEPGANGLP------GAAGERGAPGFRGPAGPNGIP 500

Query: 1373 KEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAH 1432
             E   +G A E  A G A     +G A E    GV     ++G+       G   +    
Sbjct: 501  GE---KGPAGERGAPGPAGP---RGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPP 554

Query: 1433 GIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANED 1492
            G   E    G       +G        G    D   G   E    G        G   E 
Sbjct: 555  GSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGET 614

Query: 1493 AAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVA 1552
                   P    G   +    G        G       +G   E   +G A      G  
Sbjct: 615  GPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGK 674

Query: 1553 IEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAA 1612
             +    G   E    G+A    ++G              +  +  A P    G A     
Sbjct: 675  GDAGAPG---ERGPPGLAGAPGLRGGAGPPG-------PEGGKGAAGPPGPPGAAGTPGL 724

Query: 1613 HSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHE 1672
              +  +    G       +G      A G+  +D  +G        G A +   +G    
Sbjct: 725  QGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGA 784

Query: 1673 DAVQGIANEDAVHGVAKEVAAHGVA--------NEDP-------VQGVANEDAVQGVANE 1717
              + GIA      G   E    G A        N +P         G   E    GVA  
Sbjct: 785  PGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGP 844

Query: 1718 VEVQGVAHEDAVQGIANE---DAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAV 1774
                G A     QG+  E       G      A G+     + G        G   +D  
Sbjct: 845  PGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGP 904

Query: 1775 HSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANE 1834
               A    A G      +  ++ P    G   E  + G      A G P      G+A  
Sbjct: 905  PGPAGNTGAPG------SPGVSGPKGDAGQPGEKGSPG------AQGPPGAPGPLGIAGI 952

Query: 1835 VAAHGISKEDAVQGIANEDAAQGIAKED---PIQGVANEVEVQGVAHEDAVQGIANEDAA 1891
              A G++    + G       QG+  E       G++ E    G      + G A E   
Sbjct: 953  TGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGR 1012

Query: 1892 HGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANE 1951
             G    D   G       +    E+ + G        G        G + +    G A  
Sbjct: 1013 DGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGP 1072

Query: 1952 DAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAI 2011
              A G A    A G       +G   E  A GI       G        G A +  A   
Sbjct: 1073 AGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGS 1132

Query: 2012 AKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIA 2071
              P   RG        G        G        G   E  ++         G      A
Sbjct: 1133 PGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGA 1192

Query: 2072 TEDVADGIAEDAVQGITNEEA 2092
                  G+   A+ GI  E+A
Sbjct: 1193 PGPCCGGVGAAAIAGIGGEKA 1213



 Score = 78.2 bits (191), Expect = 9e-14
 Identities = 186/962 (19%), Positives = 262/962 (27%), Gaps = 54/962 (5%)

Query: 403  AKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAA 462
            A P    G    +   G A +D   G        G+     ++G A      GI      
Sbjct: 209  AGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPA------GIPGFPGM 262

Query: 463  QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATE 522
            +G    D   G   E    G+  E   +G+  ++ A     P  A G        G A  
Sbjct: 263  KGHRGFDGRNGEKGETGAPGLKGE---NGLPGENGAPGPMGPRGAPGERGRPGLPGAAGA 319

Query: 523  DVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKP------DAAHGIANEVATQGIATE 576
               DG    D   G        G      A     P      + A G   E   QG A  
Sbjct: 320  RGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGA 379

Query: 577  DVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGV 636
                G    + + G   E+   G+     + G        G       +G A E   +G 
Sbjct: 380  QGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGA 439

Query: 637  ANEDAVQGVVNEDALHGV--VANEDAAQAIAKPDAAHGI---ANEVAAHGIANEDAAQGI 691
              E   +G   E  + GV     ED          A+G+   A E  A G        GI
Sbjct: 440  KGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGI 499

Query: 692  ANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAA 751
              E   +G A E  A G +     +G A E    G+     ++G+       G   +   
Sbjct: 500  PGE---KGPAGERGAPGPA---GPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGP 553

Query: 752  HGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANE 811
             G   E    G       +G    +   G    D   G   E    G        G   E
Sbjct: 554  PGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGE 613

Query: 812  DAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGV 871
               QG        G   +    G        G       +G   E   +G        G 
Sbjct: 614  TGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGG 673

Query: 872  VANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIA-KDAAHGITKEEAAQAI 930
              +  A      P  A      G A     +G        G A      G       Q +
Sbjct: 674  KGDAGAPGERGPPGLAGAPGLRGGAGPPGPEG------GKGAAGPPGPPGAAGTPGLQGM 727

Query: 931  AKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAV 990
              +            +G      A GV  +D  +G    +   G A +    G      +
Sbjct: 728  PGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGL 787

Query: 991  QGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANE 1050
             G+A      G   +    G A    A G   E    G   E  A G   E    G+A  
Sbjct: 788  PGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKG---ERGAPGEKGEGGPPGVAGP 844

Query: 1051 VAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGV 1110
                G +     QG+  E  + G        G A     +G+      +G        G 
Sbjct: 845  PGGSGPAGPPGPQGVKGERGSPG------GPGAAGFPGARGLPGPPGSNGNPGPPGPSGS 898

Query: 1111 ANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAA 1170
              +D   G A      G      V G   +    G      A G        GIA    A
Sbjct: 899  PGKDGPPGPAGNTGAPGSPG---VSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGA 955

Query: 1171 QGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANE 1230
            +G+A      G       QG+  E    G      A+G++ E        P    G+A  
Sbjct: 956  RGLAGPPGMPGPRGSPGPQGVKGESGKPG------ANGLSGERGPPG---PQGLPGLAGT 1006

Query: 1231 VAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGI 1290
                G      +DG+   D + G   +   +G        G        G A +   +G 
Sbjct: 1007 AGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGE 1066

Query: 1291 ANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAA 1350
            +      G       +G       +G   E   +G A     +G      A G       
Sbjct: 1067 SGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQ 1126

Query: 1351 QG 1352
            QG
Sbjct: 1127 QG 1128



 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 193/998 (19%), Positives = 265/998 (26%), Gaps = 46/998 (4%)

Query: 256  GIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEV 315
            G A      G    +   G A +D   G       +G+     ++G A      G+    
Sbjct: 207  GQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMK--- 263

Query: 316  AAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKEVTAHGVA 375
               G    D  +       A G+  E    G+  E+ A G      A G        G A
Sbjct: 264  ---GHRGFDGRNGEKGETGAPGLKGE---NGLPGENGAPGPMGPRGAPGERGRPGLPGAA 317

Query: 376  NEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAH--GIANEVAAHGIANEDAAQGIANEV 433
                  G    D   G       A     P A    G A    ++G   +    G     
Sbjct: 318  GARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHA 377

Query: 434  AAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVA 493
             A G      + G        G A    A G+       G A  +   G+       G  
Sbjct: 378  GAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLR---GGAGEP 434

Query: 494  NKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAH 553
             K+ A     P   RG A      G   ED  DG   E   +G+       G A E  A 
Sbjct: 435  GKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLP------GAAGERGAP 488

Query: 554  AIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANED 613
                P   +GI  E   +G A E  A G A      G A E    GV     ++G+    
Sbjct: 489  GFRGPAGPNGIPGE---KGPAGERGAPGPAGP---RGAAGEPGRDGVPGGPGMRGMPGSP 542

Query: 614  AVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGI 673
               G   +    G   E    G       +G        G   N+ A     +     G 
Sbjct: 543  GGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGP 602

Query: 674  ANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAV 733
              +    G   E   QG        G   +    G      + G        G   E   
Sbjct: 603  GPQ-GPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGP 661

Query: 734  QGIANEDAVHGVAKEVAAHG------VANEDPVQGVANE---DVVQGVANEVEVQGIAHE 784
            +G A      G   +  A G      +A    ++G A     +  +G A      G A  
Sbjct: 662  KGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGT 721

Query: 785  DAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGV 844
              +QG+  E    G        G      A GV  +D  +G        G A +   +G 
Sbjct: 722  PGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGE 781

Query: 845  AKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGI 904
                   G+       G   E    G      A     +P         G   E    G+
Sbjct: 782  GGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGV 841

Query: 905  ATEDVADGIA-KDAAHGITKEEAAQA---IAKQDAAHSITNEDAAQGVANEDAAHGVANE 960
            A      G A      G+  E  +      A    A  +     + G        G   +
Sbjct: 842  AGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGK 901

Query: 961  DAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGI 1020
            D   G A    A G        G A +   +G       QG        GIA    A G+
Sbjct: 902  DGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPG---AQGPPGAPGPLGIAGITGARGL 958

Query: 1021 ANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAA 1080
            A      G       QG+  E    G        G      + G+A      G      +
Sbjct: 959  AGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGS 1018

Query: 1081 QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHE 1140
             G+   D   G   +   +G      A G        G A +   +G +      G    
Sbjct: 1019 DGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGP 1078

Query: 1141 DAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1200
               +G        G   E    G A     +G      A G       QG        G 
Sbjct: 1079 AGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGP 1138

Query: 1201 AKEVAAHGVANEDAAH---AIAKPDAARGIANEVAAQG 1235
               V   G   +D          P   RG   E  ++G
Sbjct: 1139 RGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEG 1176



 Score = 76.3 bits (186), Expect = 3e-13
 Identities = 173/880 (19%), Positives = 236/880 (26%), Gaps = 68/880 (7%)

Query: 668  DAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGI 727
            D  +G   E  A G+  E+   G+  E+ A G      A G      + G A      G 
Sbjct: 269  DGRNGEKGETGAPGLKGEN---GLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGA 325

Query: 728  AHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAV 787
               D   G        G      A G   E    G    +   G   E   QG A     
Sbjct: 326  RGSDGQPGPPGPPGTAGFPGSPGAKG---EVGPAGSPGSNGAPGQRGEPGPQGHAGAQGP 382

Query: 788  QGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKE 847
             G    + + G   E+   G+       G        G      + G A E    G   E
Sbjct: 383  PGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGE 442

Query: 848  VTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATE 907
                G   E  + GV   +        ED          A+G+   G A E  A G    
Sbjct: 443  PGPRGERGEAGIPGVPGAKG-------EDGKDGSPGEPGANGLP--GAAGERGAPGFRGP 493

Query: 908  DVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVA 967
               +GI  +                             +G A E  A G A     +G A
Sbjct: 494  AGPNGIPGE-----------------------------KGPAGERGAPGPAGP---RGAA 521

Query: 968  NEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAH 1027
             E    GV     + G+       G   +    G   +    G        G    +   
Sbjct: 522  GEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFP 581

Query: 1028 GIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHED 1087
            G    D A G   E    G        G + E   QG        G   +    G     
Sbjct: 582  GPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPG---PQ 638

Query: 1088 AVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIA 1147
             +QG+       G   +    G   +    G        G   E    G+A    ++G A
Sbjct: 639  GLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGA 698

Query: 1148 NEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAH 1207
                  G        G A      G A     QG+  E    G        G      A 
Sbjct: 699  GPPGPEG------GKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGAD 752

Query: 1208 GVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKED 1267
            GV  +D       P    G A +   +G        GIA    + G   E    G +   
Sbjct: 753  GVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFP 812

Query: 1268 AVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANE---VEVQ 1324
               G   E   +G   E    G   E    G+A      G A     QGV  E       
Sbjct: 813  GAPGQNGEPGGKG---ERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGP 869

Query: 1325 GVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANED 1384
            G A     +G+     ++G        G   +D     A    A G       +G A + 
Sbjct: 870  GAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQP 929

Query: 1385 AAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANE---VAAH 1441
              +G       QG        G+A     +G+A    + G        G+  E     A+
Sbjct: 930  GEKG---SPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGAN 986

Query: 1442 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPD 1501
            G++ E    G        G A E    G    D + G        G   E+ +       
Sbjct: 987  GLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAP 1046

Query: 1502 AARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQG 1541
               G    V   G + +    G A    A G A    A G
Sbjct: 1047 GHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPG 1086



 Score = 73.9 bits (180), Expect = 2e-12
 Identities = 180/895 (20%), Positives = 231/895 (25%), Gaps = 52/895 (5%)

Query: 406  DAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGI 465
            D  +G   E  A G+  E+   G        G       +G      A G    D A+G 
Sbjct: 269  DGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARG- 327

Query: 466  AHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVA 525
               D   G        G      A G      +      + A G   E   QG A     
Sbjct: 328  --SDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPG---SNGAPGQRGEPGPQGHAGAQGP 382

Query: 526  DGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANE 585
             G    +   G   E+   G+           P    G       +G A E   +G   E
Sbjct: 383  PGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGE 442

Query: 586  DAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGV 645
                G   E  + GV       G   ED   G   E  A G+       G A E    G 
Sbjct: 443  PGPRGERGEAGIPGVP------GAKGEDGKDGSPGEPGANGLP------GAAGERGAPGF 490

Query: 646  VNEDALHGVVANEDAAQAIAKPDAA--HGIANEVAAHGIANEDAAQGIANEDAAQGIANE 703
                  +G+   +  A     P  A   G A E    G+      +G+       G   +
Sbjct: 491  RGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGK 550

Query: 704  VAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGV 763
                G   E    G       +G        G    D   G   E    G        G 
Sbjct: 551  PGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGK 610

Query: 764  ANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAA 823
              E   QG        G   +    G        G       +G   E   +G A    A
Sbjct: 611  NGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGA 670

Query: 824  QGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAK 883
             G    DA  G   E    G+A      G       +G        G             
Sbjct: 671  PG-GKGDA--GAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGM 727

Query: 884  PDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNED 943
            P    G+ + G   +    G    D   G  KD   G T        A Q          
Sbjct: 728  PGERGGLGSPGPKGDKGEPGGPGADGVPG--KDGPRGPTGPIGPPGPAGQPGDKGEGGAP 785

Query: 944  AAQGVANEDAAHGVANEDAAQGVAN---------------EVAAQGVANEDAVHGVANED 988
               G+A    + G   E    G A                E  A G   E    GVA   
Sbjct: 786  GLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPP 845

Query: 989  AVQGVANEVEVQGIAHKDAIQG---IANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQ 1045
               G A     QG+  +    G    A    A G+     ++G        G   +D   
Sbjct: 846  GGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPP 905

Query: 1046 GIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEV 1105
            G A    A G       +G A +   +G      AQG        GIA      G+A   
Sbjct: 906  GPAGNTGAPGSPGVSGPKGDAGQPGEKG---SPGAQGPPGAPGPLGIAGITGARGLAGPP 962

Query: 1106 AAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIA 1165
               G       QGV  E    G       +G      + G+A      G A E    G  
Sbjct: 963  GMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLA------GTAGEPGRDGNP 1016

Query: 1166 NEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAR 1225
              D   G       +G   E+   G        G    V   G + +      A P  A 
Sbjct: 1017 GSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAP 1076

Query: 1226 GIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQG 1280
            G A    A G        G   E  A G+       G        G A +  A G
Sbjct: 1077 GPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIG 1131



 Score = 73.2 bits (178), Expect = 3e-12
 Identities = 165/800 (20%), Positives = 213/800 (26%), Gaps = 47/800 (5%)

Query: 67   GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126
            GI      +G        G      A G      A+G        G   +  A+G     
Sbjct: 387  GINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPR 446

Query: 127  AVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIA 186
              +G A    V G   ED   G   E  A+G+       G A E  A           I 
Sbjct: 447  GERGEAGIPGVPGAKGEDGKDGSPGEPGANGL------PGAAGERGAPGFRGPAGPNGIP 500

Query: 187  NEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQ 246
             E    G       +G       +G A E    GV     ++G+       G   +    
Sbjct: 501  GEKGPAG------ERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPP 554

Query: 247  GVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 306
            G   E    G        G    +   G    D A G   E    G        G   E 
Sbjct: 555  GSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGET 614

Query: 307  AVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVA 366
               G        G   +        P    G+     T G   E   +G   E    G A
Sbjct: 615  GPQGPPGPTGPGGDKGDTG------PPGPQGLQGLPGTGGPPGE---NGKPGEPGPKGDA 665

Query: 367  KEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAA 426
                A G   +    G      L G       A     P+   G A      G A     
Sbjct: 666  GAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGA-GPPGPEGGKGAAGPPGPPGAAGTPGL 724

Query: 427  QGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKE 486
            QG+  E    G       +G   E    G      A G+  +D  +G        G A +
Sbjct: 725  QGMPGERGGLG---SPGPKGDKGEPGGPG------ADGVPGKDGPRGPTGPIGPPGPAGQ 775

Query: 487  VAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGV 546
                G         IA P  + G   E    G A    A G   ++   G   E  A G 
Sbjct: 776  PGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPG---QNGEPGGKGERGAPGE 832

Query: 547  ANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAV 606
              E     +A P    G A     QG+  E  + G        G A      G+      
Sbjct: 833  KGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPG------GPGAAGFPGARGLPGPPGS 886

Query: 607  QGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAK 666
             G        G   +D   G A    A G       +G   +    G       AQ    
Sbjct: 887  NGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKG----SPGAQGPPG 942

Query: 667  PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANE---VAAHGISKEDAVQGIANEDA 723
                 GIA    A G+A      G       QG+  E     A+G+S E    G      
Sbjct: 943  APGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPG 1002

Query: 724  AQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAH 783
              G A E    G    D + G        G   E+   G        G    V   G + 
Sbjct: 1003 LAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSG 1062

Query: 784  EDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQG 843
            +    G A    A G A    A G       +G   E  A G+       G      + G
Sbjct: 1063 DRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPG 1122

Query: 844  VAKEVTAHGVTNEDAVQGVV 863
             A +  A G       +G V
Sbjct: 1123 PAGQQGAIGSPGPAGPRGPV 1142



 Score = 70.1 bits (170), Expect = 2e-11
 Identities = 171/866 (19%), Positives = 227/866 (26%), Gaps = 74/866 (8%)

Query: 1424 GIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEV 1483
            G A +D   G        G+      +G A      G+       G   E    G     
Sbjct: 225  GPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLK 284

Query: 1484 AAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIA 1543
              +G+  E+ A     P  A G        G A     DG    D   G        G  
Sbjct: 285  GENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFP 344

Query: 1544 NEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAA 1603
                  G   E    G      A G   E   QG                AQ    P   
Sbjct: 345  GSPGAKG---EVGPAGSPGSNGAPGQRGEPGPQG-------------HAGAQGPPGPPGI 388

Query: 1604 HGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANE 1663
            +G          A    A G+       G A    A G+      +G A E    G   E
Sbjct: 389  NGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGL------RGGAGEPGKNGAKGE 442

Query: 1664 DAAQGIAHEDAVQGIAN---EDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEV 1720
               +G   E  + G+     ED   G   E  A+G+       G A E    G       
Sbjct: 443  PGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLP------GAAGERGAPGFRGPAGP 496

Query: 1721 QGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKE 1780
             G+  E   +G A E  A G        G A E    G+     ++G+           +
Sbjct: 497  NGIPGE---KGPAGERGAPG---PAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGK 550

Query: 1781 VAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGI 1840
                G   E        P   RG   +    G       DG P ++   G        G 
Sbjct: 551  PGPPGSQGESGRPGPPGPSGPRG---QPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGP 607

Query: 1841 SKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAA 1900
              ++   G        G   +    G      +QG+       G       +G   E   
Sbjct: 608  PGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLP------GTGGPPGENGKPGEPGP 661

Query: 1901 QGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANE 1960
            +G A    A     +  A G   E    G+A     +G A      G    +  +G A  
Sbjct: 662  KGDAGAPGAPGGKGDAGAPG---ERGPPGLAGAPGLRGGA------GPPGPEGGKGAAGP 712

Query: 1961 VAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGI 2020
                G A     QG+  E    G       +G        GV  +D       P    G 
Sbjct: 713  PGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGP 772

Query: 2021 ANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIA 2080
            A +   +G        GIA    + G   E      A    A G   E         G  
Sbjct: 773  AGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGE-------PGGKG 825

Query: 2081 EDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHG 2140
            E    G   E     +A      G       QGV  E  + G        G A    A G
Sbjct: 826  ERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPG------GPGAAGFPGARG 879

Query: 2141 VANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDA------AQG 2194
            +     + G        G   +D   G A      G       +G A +        AQG
Sbjct: 880  LPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQG 939

Query: 2195 VANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDA 2254
                    G+A    A+G+A      G       QGV  E    G       R       
Sbjct: 940  PPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQG 999

Query: 2255 AQGIANEDAAHGIANEDAVHGIANED 2280
              G+A      G        G+   D
Sbjct: 1000 LPGLAGTAGEPGRDGNPGSDGLPGRD 1025



 Score = 58.5 bits (140), Expect = 7e-08
 Identities = 142/717 (19%), Positives = 181/717 (25%), Gaps = 51/717 (7%)

Query: 66   HGITNEDAVQGVANEVAAQGVAN---EDAAHGVANEVAAHGV---ANEDAAQGVANEVAA 119
            +G   E   +G   E    GV     ED   G   E  A+G+   A E  A G       
Sbjct: 437  NGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGP 496

Query: 120  QGVANED---AVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDI 176
             G+  E      +G       +G A E    G+       G+       G   +      
Sbjct: 497  NGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGS 556

Query: 177  AKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAV 236
              E            +G        G    D A G   E    G        G   E   
Sbjct: 557  QGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGP 616

Query: 237  QGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHE 296
            QG        G   +    G        G       +G   E   +G A    A G   +
Sbjct: 617  QGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGD 676

Query: 297  DAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATE------ 350
                G      + G        G    +     A P    G A     QG+  E      
Sbjct: 677  AGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGS 736

Query: 351  ------------DVADGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDA 398
                          ADG+  +D   G    +   G A +   +G      L G       
Sbjct: 737  PGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPG------- 789

Query: 399  AQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAH 458
               IA P  + G   E    G A    A G   E    G   E    G   E    G+A 
Sbjct: 790  ---IAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKG---ERGAPGEKGEGGPPGVAG 843

Query: 459  EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQG 518
                 G A     QG+  E    G        G A    A  +  P  + G        G
Sbjct: 844  PPGGSGPAGPPGPQGVKGERGSPG------GPGAAGFPGARGLPGPPGSNGNPGPPGPSG 897

Query: 519  IATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDV 578
               +D   G A      G        G A +           A G        GIA    
Sbjct: 898  SPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKG---SPGAQGPPGAPGPLGIAGITG 954

Query: 579  ADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVAN 638
            A G+A      G        GV  E    G        G        G+A      G   
Sbjct: 955  ARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDG 1014

Query: 639  EDAVQGVVNEDALHGVVANEDAAQAIAKPDAA--HGIANEVAAHGIANEDAAQGIANEDA 696
                 G+   D   G   +     +   P A    G    V   G + +    G A    
Sbjct: 1015 NPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAG 1074

Query: 697  AQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHG 753
            A G A    A G       +G   E  A GI       G        G A +  A G
Sbjct: 1075 APGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIG 1131



 Score = 45.1 bits (105), Expect = 8e-04
 Identities = 94/465 (20%), Positives = 121/465 (26%), Gaps = 30/465 (6%)

Query: 1798 PDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANE--DAA 1855
            P A     N    QG   +    GIP  +   G+  +  + G        GI        
Sbjct: 92   PTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPG---SPGPPGICESCPTGP 148

Query: 1856 QGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANE 1915
            Q  + +     V + V V G+A      G A      G        G       Q    E
Sbjct: 149  QNYSPQYDSYDVKSGVAVGGLA---GYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGE 205

Query: 1916 DAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGI 1975
                G S      G        G   E    G   E    G        GI      +G 
Sbjct: 206  PGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGH 265

Query: 1976 ANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVA 2035
               D   G   E    G+  E+   G+  E+ A     P  A G        G A     
Sbjct: 266  RGFDGRNGEKGETGAPGLKGEN---GLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGN 322

Query: 2036 DGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQA 2095
            DG    D   G               A G           A     +   G   E   Q 
Sbjct: 323  DGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGP-------AGSPGSNGAPGQRGEPGPQG 375

Query: 2096 IAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVA 2155
             A      G    + + G   E+   G+       G        G       +G A E  
Sbjct: 376  HAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPG 435

Query: 2156 AQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGV---ANEDAAQG 2212
              G   E   +G   E  + G+       G   ED   G   E  A+G+   A E  A G
Sbjct: 436  KNGAKGEPGPRGERGEAGIPGVP------GAKGEDGKDGSPGEPGANGLPGAAGERGAPG 489

Query: 2213 VANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQG 2257
                    G+  E   +G A E    G A    A      D   G
Sbjct: 490  FRGPAGPNGIPGE---KGPAGERGAPGPAGPRGAAGEPGRDGVPG 531


>gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens]
          Length = 1860

 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 157/875 (17%), Positives = 251/875 (28%), Gaps = 70/875 (8%)

Query: 581  GIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANED 640
            G++   A  G   ++ + G++      G        G A     QG        G     
Sbjct: 679  GLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQG------QPGPEGSP 732

Query: 641  AVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGI 700
              +G      L G V +         P  + G        G+   D  +G+      +G 
Sbjct: 733  GAKGYPGRQGLPGPVGDPG-------PKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGK 785

Query: 701  ANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPV 760
                   G+  E    G+       G+     V G+  +    GV   +   G      +
Sbjct: 786  MGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGD---LGVLGPIGYPGPKGMKGL 842

Query: 761  QGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANE 820
             G   E  ++G   E  V G++ +   QG        G        G   +   +G    
Sbjct: 843  MGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGF 902

Query: 821  DAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQA 880
                G        G   ++  +G+  +  A G+       G   +E   G          
Sbjct: 903  PGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMG---------- 952

Query: 881  IAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAH-GITKEEAAQAIAKQDAAHSI 939
               P  A G+  EG        G    D   G   D    G   E+             I
Sbjct: 953  ---PPGAPGL--EGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGI 1007

Query: 940  TNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEV 999
              E   +G+       GV     + G        G   E    G        G+      
Sbjct: 1008 VGEKGDRGMMGPP---GVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGR 1064

Query: 1000 QGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKE 1059
            +G    D   G A E  + G+       G       QG+A E    G        G S  
Sbjct: 1065 RGPRGPD---GPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGP 1121

Query: 1060 DAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVA---KEVAAHGVANEDPV 1116
               +G+  E   QG        G        G   E  + G A    ++   G   E  +
Sbjct: 1122 PGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGL 1181

Query: 1117 QGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANE 1176
             G   E  ++G +  +   G+  +   +G    D  HG   +    G        G+   
Sbjct: 1182 IGQRGEPGLEGDSGPMGPDGLKGD---RGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGV 1238

Query: 1177 DAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGI 1236
               +G + +   +G        G   ++   GV  +        P  +RG      A G 
Sbjct: 1239 RGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGR 1298

Query: 1237 ATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAA 1296
                   G+A  D   G+   +   G   E   QG   +  A+G       +G   +   
Sbjct: 1299 MGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQG--EDGKAEGPPGPPGDRGPVGDRGD 1356

Query: 1297 QGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANE 1356
            +G   E    G   ++ +QG+  +   QG       +G      + G       QG A  
Sbjct: 1357 RG---EPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKA-- 1411

Query: 1357 DAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGV 1416
                         G      VQG+      +G+     ++G+A  D + G        G 
Sbjct: 1412 -------------GAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPG------RDGQ 1452

Query: 1417 AHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQG 1451
            A +   QG   +    G A +    G+A    AQG
Sbjct: 1453 AGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQG 1487



 Score = 72.8 bits (177), Expect = 4e-12
 Identities = 156/869 (17%), Positives = 249/869 (28%), Gaps = 62/869 (7%)

Query: 1379 GIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEV 1438
            G+     A+G  K DP  G++   A  G   ++ + G++      G        G A   
Sbjct: 664  GLPGPPGAKG-QKGDP--GLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHP 720

Query: 1439 AAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIA 1498
               G    + + G       QG+       G        G+       G+   D    + 
Sbjct: 721  GEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLP---GLFGLPGSDGERGLP 777

Query: 1499 KPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQ 1558
                 RG        G+  E    G+       G+       G+  ++ V G       +
Sbjct: 778  GVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPK 837

Query: 1559 GV------VKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAA 1612
            G+      V E    G   E  V GV  +         +  +Q +     A G    +  
Sbjct: 838  GMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQG----DKGSQGLPGFPGARGKPGPLG- 892

Query: 1613 HSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHE 1672
              + +K +  G       +G   ++   G   ++  +G+  +  A+G+       G   +
Sbjct: 893  -KVGDKGSI-GFPGPPGPEGFPGDIGPPG---DNGPEGMKGKPGARGLPGPRGQLGPEGD 947

Query: 1673 DAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGI 1732
            +   G      + G        G    D V+G   +    G   E    G        GI
Sbjct: 948  EGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGI 1007

Query: 1733 ANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAA 1792
              E    G+   +   G+     + G        G   E             G+      
Sbjct: 1008 VGEKGDRGM---MGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGR 1064

Query: 1793 HAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANE 1852
                 PD   G A E  ++G+       G P      GVA E    G      + G +  
Sbjct: 1065 RGPRGPD---GPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGP 1121

Query: 1853 DAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDI 1912
               +G+  E   QG    +   G        G   E    G A      G       Q +
Sbjct: 1122 PGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGL 1181

Query: 1913 ANEDAAQGISKE------DAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGI 1966
              +    G+  +      D ++G        G   E   +G+  ED   G        G 
Sbjct: 1182 IGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGP 1241

Query: 1967 ANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAA 2026
              +   QG      A+G       +G   +    GV  +        P  +RG      A
Sbjct: 1242 EGKSGKQGEKGRTGAKG------AKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGA 1295

Query: 2027 QGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAE--DAV 2084
             G        G+A  D   G+        +  P        +G   E   DG AE     
Sbjct: 1296 PGRMGAQGEPGLAGYDGHKGIVG-----PLGPP------GPKGEKGEQGEDGKAEGPPGP 1344

Query: 2085 QGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANE 2144
             G       +    +    G   ++  QG+  +   QG        G      + G    
Sbjct: 1345 PGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGP 1404

Query: 2145 DAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGV 2204
               QG A      G      VQG+      +G+  +  ++GIA  D   G   +    G 
Sbjct: 1405 KGKQGKA------GAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGE 1458

Query: 2205 ANED---AAQGVANEVAAQGVANEDAAQG 2230
              +D      G A +    GVA    AQG
Sbjct: 1459 QGDDGDPGPMGPAGKRGNPGVAGLPGAQG 1487



 Score = 70.5 bits (171), Expect = 2e-11
 Identities = 146/875 (16%), Positives = 244/875 (27%), Gaps = 59/875 (6%)

Query: 607  QGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAK 666
            +G      + G+   D  +G+       G        GV  E    G+  N      +  
Sbjct: 756  RGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGEL-GLPG 814

Query: 667  PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG 726
            P    G+  ++   G       +G+      +G+   V   G+  +   QG+       G
Sbjct: 815  PPGVPGLIGDLGVLGPIGYPGPKGM------KGLMGSVGEPGLKGDKGEQGVPGVSGDPG 868

Query: 727  IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDA 786
               +   QG+       G    +   G   +    G       +G   ++   G   ++ 
Sbjct: 869  FQGDKGSQGLPGFPGARGKPGPL---GKVGDKGSIGFPGPPGPEGFPGDIGPPG---DNG 922

Query: 787  VQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAK 846
             +G+  +  A G+       G   ++   G       +G        G    D  +G   
Sbjct: 923  PEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPG 982

Query: 847  EVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIAT 906
            +    G   E    G +      G+V  +     +  P       + G        G   
Sbjct: 983  DPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPG 1042

Query: 907  EDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGV 966
            E    G     + G      A+             E  ++G+       G       QGV
Sbjct: 1043 EPGPQG--PPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGV 1100

Query: 967  ANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAA 1026
            A E    G      + G +     +G+  E   QG        G        G   E   
Sbjct: 1101 AGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGL 1160

Query: 1027 HGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHE 1086
             G A      G       QG+  +    G+  +    G    D  +G   +    G   E
Sbjct: 1161 PGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMG---PDGLKGDRGDPGPDGEHGE 1217

Query: 1087 DAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGI 1146
               +G+  ED   G        G   +   QG       +G       +G   +    G+
Sbjct: 1218 KGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGA------KGYQGQLGEMGV 1271

Query: 1147 ANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAA 1206
              +    G      + G      A G        G+A  D  +GI       G   E   
Sbjct: 1272 PGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGE 1331

Query: 1207 HGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKE 1266
             G   +  A     P   RG   +   +G                     E    G   +
Sbjct: 1332 QG--EDGKAEGPPGPPGDRGPVGDRGDRG---------------------EPGDPGYPGQ 1368

Query: 1267 DAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVA---NEDPIQGVANEVEV 1323
            + VQG+  +   QG       +G      ++G       QG A       +QG+      
Sbjct: 1369 EGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGP 1428

Query: 1324 QGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANE 1383
            +GV     ++GIA  D   G   +   QG   +D           +G      V G+   
Sbjct: 1429 RGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRG---NPGVAGLPGA 1485

Query: 1384 DAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGI 1443
                G   E  + G       +G      + G       QG        G + E+   G+
Sbjct: 1486 QGPPGFKGESGLPGQLGPPGKRGTEGRTGLPG------NQGEPGSKGQPGDSGEMGFPGM 1539

Query: 1444 ANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHG 1478
            A     +G   +   +GI       G+  ++ + G
Sbjct: 1540 AGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVG 1574



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 120/706 (16%), Positives = 192/706 (27%), Gaps = 57/706 (8%)

Query: 1623 GIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 1682
            G+   D  +G+       G        G+  E    G+       G+     V G+  + 
Sbjct: 766  GLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDL 825

Query: 1683 AVHGVAKEVAAHGV------ANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANED 1736
             V G        G+        E  ++G   E  V GV+ +   QG      + G     
Sbjct: 826  GVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGAR 885

Query: 1737 AAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANE------D 1790
               G   +V   G        G        G   ++    +  +  A G+         +
Sbjct: 886  GKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPE 945

Query: 1791 AAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIA 1850
                   P  A G+  +   +G       DG+  E    G    V   G        G+ 
Sbjct: 946  GDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFM---GFIGLV 1002

Query: 1851 NEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQ 1910
             E    G   +  + G       +G      + G        G      ++G      A+
Sbjct: 1003 GEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAK 1062

Query: 1911 DIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANED 1970
                     G + E   +G+      QG       QG+A E    G        G +   
Sbjct: 1063 GRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPP 1122

Query: 1971 AAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIA 2030
              +G+  E   QG        G        G   E      A      G       QG+ 
Sbjct: 1123 GTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLI 1182

Query: 2031 TEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGI-ANEGIATEDVADG----------- 2078
             +    G+  +    G       +    PD  HG    EG+  ED   G           
Sbjct: 1183 GQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPE 1242

Query: 2079 --IAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEV 2136
                +   +G T  + A+    Q    G+  +    G      ++G      A G     
Sbjct: 1243 GKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQ 1302

Query: 2137 AAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQ--------------------- 2175
               G+A  D  +G+   +   G   E   QG   + E                       
Sbjct: 1303 GEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGD 1362

Query: 2176 -GIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANE 2234
             G   ++ +QG+  +   QG        G      ++G       QG A     +GV   
Sbjct: 1363 PGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGV--- 1419

Query: 2235 VAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVHGIANED 2280
                G+      R +      +GIA  D   G   +    G   +D
Sbjct: 1420 ---QGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDD 1462



 Score = 61.2 bits (147), Expect = 1e-08
 Identities = 149/871 (17%), Positives = 244/871 (28%), Gaps = 79/871 (9%)

Query: 355  GIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANE 414
            G+   D   G+       G        GV  E    G+  N      +  P    G+  +
Sbjct: 766  GLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGEL-GLPGPPGVPGLIGD 824

Query: 415  VAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGI 474
            +   G       +G+   + + G   E  ++G   E    G++ +   QG      + G 
Sbjct: 825  LGVLGPIGYPGPKGMKGLMGSVG---EPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGF 881

Query: 475  ANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAV 534
                   G   +V   G      +     P    G   ++   G   ++  +G+  +   
Sbjct: 882  PGARGKPGPLGKVGDKG------SIGFPGPPGPEGFPGDIGPPG---DNGPEGMKGKPGA 932

Query: 535  HGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANE 594
             G+       G   ++       P  A G+  +   +G       DG+  E    G    
Sbjct: 933  RGLPGPRGQLGPEGDEGPMG---PPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGP 989

Query: 595  VAVHG------VAIEDAVQGVANEDAVHG---VANEDAAQGIAKEVTAHGVANEDAVQGV 645
            V   G      +  E  + G   +  + G   V     + G        G   E   QG 
Sbjct: 990  VGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGP 1049

Query: 646  VNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVA 705
                   G+      A+    P    G A E  + G+      QG       QG+A E  
Sbjct: 1050 PGSRGPPGM----RGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERG 1105

Query: 706  AHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVAN 765
              G      + G +     +G+  E   QG        G        G   E  + G A 
Sbjct: 1106 HLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAG 1165

Query: 766  EDVVQGVANEVEVQGIAHEDAVQGIANE------DAAHGIANEVAAHGVANEDAAQGVAN 819
                 G       QG+  +    G+  +      D   G   +    G   E   +G+  
Sbjct: 1166 MKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMG 1225

Query: 820  EDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTN------EDAVQGVVNEEALHGVVA 873
            ED   G      V G   +   QG      A G         E  V G        G   
Sbjct: 1226 EDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKG 1285

Query: 874  NEDAAQAIAKPDAAHGIANEGVANEVAAQGIAT------------EDVADGIAKDAA--- 918
            +  +      P         G+A     +GI              E   DG A+      
Sbjct: 1286 SRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPP 1345

Query: 919  --------HGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEV 970
                     G   E        Q+    +  +   QG        G      ++G     
Sbjct: 1346 GDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPK 1405

Query: 971  AAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIA 1030
              QG A      G      VQG+      +G+  +  ++GIA  D   G        G A
Sbjct: 1406 GKQGKA------GAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPG------RDGQA 1453

Query: 1031 NEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQ 1090
             +   QG   +    G A +    G++     QG        G+  +    G    +   
Sbjct: 1454 GQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRT 1513

Query: 1091 GIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANED 1150
            G+       G        G + E    G+A     +G   ++  +G+       G+  ++
Sbjct: 1514 GLPGNQGEPG---SKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKE 1570

Query: 1151 AAHGIANEVAAHGIANEDAAQGIANEDAAQG 1181
               G    +   G+      +G   +   QG
Sbjct: 1571 GIVGPLGILGPSGLPGPKGDKGSRGDWGLQG 1601



 Score = 61.2 bits (147), Expect = 1e-08
 Identities = 108/583 (18%), Positives = 157/583 (26%), Gaps = 41/583 (7%)

Query: 72   DAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGV 131
            D V+G   +    G   E    G    V   G+  E   +G+   +   GV       G 
Sbjct: 975  DGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGM---MGPPGVPGPKGSMGH 1031

Query: 132  ANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAA 191
                   G   E   QG        G+      +G    D     A E  ++ +      
Sbjct: 1032 PGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGP---AGEQGSRGLKGPPGP 1088

Query: 192  QGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHE 251
            QG       QG+A E    G      + G +     +G+  E   QG    +   G    
Sbjct: 1089 QGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGP 1148

Query: 252  DAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHE------DAVQGIANE 305
                G   E    G        G       QG+  +    G+  +      D ++G   +
Sbjct: 1149 KGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGD 1208

Query: 306  DAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGV 365
                G   E    G+  ED       P    G+      +G + +    G      A G 
Sbjct: 1209 PGPDGEHGEKGQEGLMGEDG------PPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGY 1262

Query: 366  AKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDA 425
              ++   GV  +    G        G +           P  A G        G+A  D 
Sbjct: 1263 QGQLGEMGVPGDPGPPGTPGPKGSRGSLG----------PTGAPGRMGAQGEPGLAGYDG 1312

Query: 426  AQGIANEVAAHGISKEDAVQG----IANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVH 481
             +GI   +   G   E   QG            G       +G   E    G   ++ V 
Sbjct: 1313 HKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQ 1372

Query: 482  GVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEV 541
            G+  +    G            P  ++G       QG A      G      V G+    
Sbjct: 1373 GLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKA------GAPGRRGVQGLQGLP 1426

Query: 542  AAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVA 601
               GV        IA PD   G   +   QG   E   DG        G      V G+ 
Sbjct: 1427 GPRGVVGRQGLEGIAGPDGLPGRDGQAGQQG---EQGDDGDPGPMGPAGKRGNPGVAGLP 1483

Query: 602  IEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQG 644
                  G   E  + G       +G        G   E   +G
Sbjct: 1484 GAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKG 1526



 Score = 58.9 bits (141), Expect = 6e-08
 Identities = 141/827 (17%), Positives = 228/827 (27%), Gaps = 68/827 (8%)

Query: 67   GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHG---VANEDAAQGVANEVAAQGVA 123
            G+  E    G+       G+       G+  ++   G          +G+   V   G+ 
Sbjct: 793  GVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLK 852

Query: 124  NEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQ 183
             +   QGV       G   +   QG+     A G   +    G   +  +         +
Sbjct: 853  GDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARG---KPGPLGKVGDKGSIGFPGPPGPE 909

Query: 184  DIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEV 243
                +    G   ++  +G+  +  A+G+       G   ++   G      ++G     
Sbjct: 910  GFPGDIGPPG---DNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRK 966

Query: 244  EVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIA 303
               G    D V+G   +    G   E    G        GI  E   +G+     V G  
Sbjct: 967  GFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPK 1026

Query: 304  NEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAH 363
                  G+   +   G            P    G       +G       DG A E  + 
Sbjct: 1027 GSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRG------PDGPAGEQGSR 1080

Query: 364  GVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANE 423
            G+       G       QGV  E    G          I  P    G        G+  E
Sbjct: 1081 GLKGPPGPQGRPGRPGQQGVAGERGHLG----SRGFPGIPGPSGPPG------TKGLPGE 1130

Query: 424  DAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGV 483
               QG    +   G        G   E    G A      G       QG+  +    G+
Sbjct: 1131 PGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGL 1190

Query: 484  AKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAA 543
              +    G            PD   G   E   +G+  ED   G      V G   +   
Sbjct: 1191 EGDSGPMGPDGLKGDRGDPGPDGEHG---EKGQEGLMGEDGPPGPPGVTGVRGPEGKSGK 1247

Query: 544  HGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIE 603
             G      A        A G   ++   G+  +    G      + G        G    
Sbjct: 1248 QGEKGRTGA------KGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGA 1301

Query: 604  DAVQGVANEDAVHGVA---------NEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGV 654
                G+A  D   G+           E   QG  ++  A G       +G V +    G 
Sbjct: 1302 QGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQG--EDGKAEGPPGPPGDRGPVGDRGDRGE 1359

Query: 655  VAN-----EDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGI 709
              +     ++  Q +       G        G      ++G       QG A      G 
Sbjct: 1360 PGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRG- 1418

Query: 710  SKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVV 769
                 VQG+      +G+     ++GIA  D + G        G A +   QG   +   
Sbjct: 1419 -----VQGLQGLPGPRGVVGRQGLEGIAGPDGLPG------RDGQAGQQGEQGDDGDPGP 1467

Query: 770  QGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAA------QGVANEDAA 823
             G A +    G+A     QG        G+  ++   G    +        QG       
Sbjct: 1468 MGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQ 1527

Query: 824  QGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHG 870
             G + E    G+A     +G   ++   G+       G++ +E + G
Sbjct: 1528 PGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVG 1574



 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 82/495 (16%), Positives = 139/495 (28%), Gaps = 33/495 (6%)

Query: 1798 PDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQG 1857
            P  +RG        G+   D   G+P      G        G+  E    G+       G
Sbjct: 752  PKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELG 811

Query: 1858 IAKEDPIQGVANEVEVQG---VAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAN 1914
            +     + G+  ++ V G         ++G+       G+  +   QG+           
Sbjct: 812  LPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQG 871

Query: 1915 EDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQG 1974
            +  +QG+       G   +    G   +    G       +G   ++   G   ++  +G
Sbjct: 872  DKGSQGLP---GFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPG---DNGPEG 925

Query: 1975 IANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDV 2034
            +  +  A+G+       G   ++   G            P  A G+  +   +G      
Sbjct: 926  MKGKPGARGLPGPRGQLGPEGDEGPMG------------PPGAPGLEGQPGRKGFPGRPG 973

Query: 2035 ADGIANEDAAHGVANEDAAQAIAKPDAAHGIANE-GIATEDVADGIAEDAVQGITNEEAA 2093
             DG+  E    G       Q         G+  E GI  E    G+      G+   + +
Sbjct: 974  LDGVKGEPGDPGRPGPVGEQGFM---GFIGLVGEPGIVGEKGDRGMM--GPPGVPGPKGS 1028

Query: 2094 QAIAKQDAAHGITKEDAAQGVTNEVA------AQGVANEDAAHGVANEVAAHGVANEDAA 2147
                      G   E   QG            A+G        G A E  + G+      
Sbjct: 1029 MGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGP 1088

Query: 2148 QGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANE 2207
            QG       QGVA E    G      + G +     +G+  E   QG    +   G    
Sbjct: 1089 QGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGP 1148

Query: 2208 DAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGI 2267
                G   E    G A      G        G+  +     +  +    G        G 
Sbjct: 1149 KGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGD 1208

Query: 2268 ANEDAVHGIANEDAV 2282
               D  HG   ++ +
Sbjct: 1209 PGPDGEHGEKGQEGL 1223



 Score = 45.8 bits (107), Expect = 5e-04
 Identities = 69/400 (17%), Positives = 120/400 (30%), Gaps = 30/400 (7%)

Query: 56   DIANEDADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVAN 115
            D  +   D  HG   ++ + G        GV       G + +    G      A+G   
Sbjct: 1205 DRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQG 1264

Query: 116  EVAAQGVANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQD 175
            ++   GV  +    G       +G        G        G+A  D  +GI        
Sbjct: 1265 QLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPG 1324

Query: 176  IAKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDA 235
               E   Q    +  A+G       +G   +   +G   E    G   ++ VQG+  +  
Sbjct: 1325 PKGEKGEQ--GEDGKAEGPPGPPGDRGPVGDRGDRG---EPGDPGYPGQEGVQGLRGKPG 1379

Query: 236  VQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAH 295
             QG       +G        G      A G   +    G       QG+      +G+  
Sbjct: 1380 QQGQPGHPGPRG------WPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVG 1433

Query: 296  EDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADG 355
               ++GIA  D + G   +    G   +D                +    G A +    G
Sbjct: 1434 RQGLEGIAGPDGLPGRDGQAGQQGEQGDD---------------GDPGPMGPAGKRGNPG 1478

Query: 356  IANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEV 415
            +A    A G        G+  +    G    +   G+  N+    +  +P    G + E+
Sbjct: 1479 VAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQP----GDSGEM 1534

Query: 416  AAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG 455
               G+A     +G   ++   GI       G+  ++   G
Sbjct: 1535 GFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVG 1574


>gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens]
          Length = 1669

 Score = 68.9 bits (167), Expect = 5e-11
 Identities = 109/585 (18%), Positives = 166/585 (28%), Gaps = 19/585 (3%)

Query: 956  GVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEV-----QGIAHKDAIQG 1010
            G        G+  ++   G       +G+     VQG   E  V     +G+     I G
Sbjct: 693  GPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPG 752

Query: 1011 IANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDA 1070
               E  + G+      HG       QGI  E    G+   V + G+       G      
Sbjct: 753  TPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGV-PGIGPPGARGPPG 811

Query: 1071 AQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVAN 1130
             QG        GI  E    G    D + G   +  A G+       G+      QG   
Sbjct: 812  GQGPPGLSGPPGIKGEKGFPGFPGLD-MPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPG 870

Query: 1131 EVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQG 1190
                 G   E  V G   +  + G    V A G+  E    G       +G       +G
Sbjct: 871  IPGFPGSKGEMGVMGTPGQPGSPG---PVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKG 927

Query: 1191 IANEDAVHGVAKEV---AAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIAN 1247
                    G   +V   +  G   +        P   +G   +    G+  +D   G   
Sbjct: 928  DVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPG 987

Query: 1248 EDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQG 1307
            +    G        G       +G        G   E  V GI     + G+  +   +G
Sbjct: 988  QPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKG 1047

Query: 1308 VANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDA 1367
               +    G+     + G+  E   QGIA    + G   E  + GI     +  +     
Sbjct: 1048 EKGQAGPPGIG----IPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPG 1103

Query: 1368 AQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIAN 1427
            + G      + G   +    G+     V+G A      G       +G    D + G A 
Sbjct: 1104 SVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAG 1163

Query: 1428 EDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHG 1487
            E    G+       G       +G   E    G+A    + G   E    G        G
Sbjct: 1164 EKGEPGLPGR-GFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPG 1222

Query: 1488 VANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHG 1532
            +      HA   P   RG   +    G+       G+   D   G
Sbjct: 1223 LPG-SPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKG 1266



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 143/803 (17%), Positives = 227/803 (28%), Gaps = 84/803 (10%)

Query: 742  VHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEV-----QGIAHEDAVQGIANEDAA 796
            V G+  ++   G        G+     VQG   E  V     +G+     + G   E  +
Sbjct: 700  VDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGS 759

Query: 797  HGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNE 856
             G+      HG       QG+  E    G+       GV       G        G    
Sbjct: 760  IGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPG-IGPPGARGPPGGQGPPGL 818

Query: 857  DAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKD 916
                G+  E+   G                  G+   G   +  AQG+            
Sbjct: 819  SGPPGIKGEKGFPGF----------------PGLDMPGPKGDKGAQGLP----------- 851

Query: 917  AAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVA 976
               GIT +     +  Q  A  I     ++G        GV       G    V A G+ 
Sbjct: 852  ---GITGQSGLPGLPGQQGAPGIPGFPGSKG------EMGVMGTPGQPGSPGPVGAPGLP 902

Query: 977  NEDAVHGV------ANEDAVQGVANEVEVQG------IAHKDAIQGIANEDAAHGIANEV 1024
             E   HG         +  ++G   +V + G           +++G   +    G    +
Sbjct: 903  GEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPI 962

Query: 1025 AAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIA 1084
               G   +    G+  +D   G   +    G        G       +G        G  
Sbjct: 963  GEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTP 1022

Query: 1085 HEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQ 1144
             E  V GI       G+  +  A G   +    G+     + G+  E   QG+A      
Sbjct: 1023 GEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGI----GIPGLRGEKGDQGIAGFPGSP 1078

Query: 1145 GIANEDAAHGIANEVAAHGIANE------DAAQGIANEDAAQGIAHEDAVQGIANEDAVH 1198
            G   E  + GI     + G+           + G+  E   +G+   D + G+  E  + 
Sbjct: 1079 GEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLP 1138

Query: 1199 GVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEV 1258
            G        G   E  +      D   G A E    G+       G        G   EV
Sbjct: 1139 GTPGPTGPAGQKGEPGS------DGIPGSAGEKGEPGLPGRGF-PGFPGAKGDKGSKGEV 1191

Query: 1259 AAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPV--QGVANEDPIQG 1316
               G++    + G   E   QG       QG      + G A E P   +G   +  + G
Sbjct: 1192 GFPGLAGSPGIPGSKGE---QGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPG 1248

Query: 1317 VANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDA 1376
            +   +   G+   D V+G   +    G        G   +   Q +     + GI+    
Sbjct: 1249 LPGPMGPPGLPGIDGVKG---DKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKG 1305

Query: 1377 VQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIAN 1436
              G       QG      +QG+  +   QGV     + G         I   +   G+  
Sbjct: 1306 DMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEP--GLPG 1363

Query: 1437 EVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHA 1496
                 G+       G   +    G+       GI   D   G   E+   G A       
Sbjct: 1364 PEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEM---GPAGPTGPRG 1420

Query: 1497 IAKPDAARGIANEVATQGIATED 1519
               P    G+   +   G  + D
Sbjct: 1421 FPGPPGPDGLPGSMGPPGTPSVD 1443



 Score = 63.2 bits (152), Expect = 3e-09
 Identities = 136/764 (17%), Positives = 218/764 (28%), Gaps = 62/764 (8%)

Query: 690  GIANEDAAQGIANEVAAHGISKEDAVQGIANEDAA-----QGIAHEDAVQGIANEDAVHG 744
            G+  +    G       +G+     VQG   E        +G+     + G   E    G
Sbjct: 702  GLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIG 761

Query: 745  VAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVA 804
            V      HG      +QG+  E    G+   V   G      V GI       G      
Sbjct: 762  VPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPG------VPGI----GPPGARGPPG 811

Query: 805  AHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVN 864
              G        G+  E    G    D + G   +  AQG+       G+T +  + G+  
Sbjct: 812  GQGPPGLSGPPGIKGEKGFPGFPGLD-MPGPKGDKGAQGLP------GITGQSGLPGLPG 864

Query: 865  EEALHGV---VANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAA--- 918
            ++   G+     ++     +  P         G    V A G+  E    G    +    
Sbjct: 865  QQGAPGIPGFPGSKGEMGVMGTP------GQPGSPGPVGAPGLPGEKGDHGFPGSSGPRG 918

Query: 919  -HGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVAN 977
              G+  ++    +  +  +    +  + +G   +    G       +G   +    GV  
Sbjct: 919  DPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPG 978

Query: 978  EDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQG 1037
            +D   G   +   +G        G       +G        G   E    GI     + G
Sbjct: 979  KDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPG 1038

Query: 1038 IANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHED---AVQGIAN 1094
            +  +  A+G   +    GI     + G+  E   QGIA    + G   E     + G+  
Sbjct: 1039 LPGDKGAKGEKGQAGPPGI----GIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPG 1094

Query: 1095 EDAVHGVAKEV---AAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDA 1151
               + G    V    + G+  E   +G+   D + GV  E  + G        G   E  
Sbjct: 1095 SPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPG 1154

Query: 1152 AHGIANEVAAH-----------GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1200
            + GI                  G       +G   E    G+A    + G   E    G 
Sbjct: 1155 SDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGP 1214

Query: 1201 AKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAA 1260
                   G+      HA   P   RG   +    G+       G+   D   GV  +   
Sbjct: 1215 PGPQGQPGLPG-SPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGID---GVKGDKGN 1270

Query: 1261 HGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANE 1320
             G      V G   +   QG+       GI       G       QG      +QG+  +
Sbjct: 1271 PGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGD 1330

Query: 1321 VEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGI 1380
               QGV     + G       + I   +   G+   +    +       G   +  V G+
Sbjct: 1331 QGDQGVPGAKGLPGPPGPPGPYDIIKGE--PGLPGPEGPPGLKGLQGLPGPKGQQGVTGL 1388

Query: 1381 ANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQG 1424
                   GI   D   G   E    G        G    D + G
Sbjct: 1389 VGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPG 1432



 Score = 57.4 bits (137), Expect = 2e-07
 Identities = 119/688 (17%), Positives = 198/688 (28%), Gaps = 42/688 (6%)

Query: 672  GIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHED 731
            G+      HG       QGI  E    G+   V + G      V GI     A+G     
Sbjct: 761  GVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPG------VPGI-GPPGARGPPGGQ 813

Query: 732  AVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIA 791
               G++    + G        G+    P +G      + G+  +  + G+  +    GI 
Sbjct: 814  GPPGLSGPPGIKGEKGFPGFPGLDMPGP-KGDKGAQGLPGITGQSGLPGLPGQQGAPGIP 872

Query: 792  NEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAH 851
                + G   E+   G   +  + G      A G+  E   HG       +G        
Sbjct: 873  GFPGSKG---EMGVMGTPGQPGSPGPV---GAPGLPGEKGDHGFPGSSGPRG-------- 918

Query: 852  GVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVAD 911
                +  ++G   +  L G   + D     +          +G    +  +G   +    
Sbjct: 919  ----DPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTP 974

Query: 912  GI-AKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEV 970
            G+  KD   G   +   +                 +G        G   E    G+    
Sbjct: 975  GVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQ 1034

Query: 971  AAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIA 1030
             + G+  +    G   +    G+     + G+  +   QGIA    + G   E  + GI 
Sbjct: 1035 GSPGLPGDKGAKGEKGQAGPPGIG----IPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIP 1090

Query: 1031 NEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQ 1090
                + G+     + G        G   +  + G+      +G A      G       +
Sbjct: 1091 GMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQK 1150

Query: 1091 GIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANED 1150
            G    D + G A E    G+       G       +G   EV   G+A    + G   E 
Sbjct: 1151 GEPGSDGIPGSAGEKGEPGLPGRG-FPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQ 1209

Query: 1151 AAHGIANEVAAHGIANE--DAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHG 1208
               G        G+      A +G   +   QG      + G      + G+       G
Sbjct: 1210 GFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKG 1269

Query: 1209 VANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDA 1268
                  A  +  P    G       QG+     + GI       G        G      
Sbjct: 1270 NPGWPGAPGVPGPKGDPGF------QGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPG 1323

Query: 1269 VQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAH 1328
            +QGI  +   QG+     + G         I K +P  G+   +   G+     + G   
Sbjct: 1324 LQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEP--GLPGPEGPPGLKGLQGLPGPKG 1381

Query: 1329 EDAVQGIANEDAAHGIANEDAAQGIANE 1356
            +  V G+       GI   D A G   E
Sbjct: 1382 QQGVTGLVGIPGPPGIPGFDGAPGQKGE 1409



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 80/423 (18%), Positives = 131/423 (30%), Gaps = 30/423 (7%)

Query: 1821 GIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHED 1880
            G P E  + GV      HG      +QGI  E    G+       GV   +   G     
Sbjct: 752  GTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPG-IGPPGARGPP 810

Query: 1881 AVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDA--AQGISKEDAVQGIANQDAAQG 1938
              QG        GI  E    G    D      ++ A    GI+ +  + G+  Q  A G
Sbjct: 811  GGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPG 870

Query: 1939 I------AKEDAVQGIANED------AAQGIANEVAAHGIANEDAAQ---GIANEDAAQG 1983
            I        E  V G   +        A G+  E   HG       +   G+  +    G
Sbjct: 871  IPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVG 930

Query: 1984 IAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDA 2043
            +  +       +  ++ G   +        P   +G   +    G+  +D   G   +  
Sbjct: 931  LPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPG 990

Query: 2044 AH---GVANEDAAQAIAKP-DAAHGIANEGIATEDVADGI-AEDAVQGITNEEAAQAIAK 2098
                 G++    A  +  P  +  G+   G   E    GI       G+  ++ A+    
Sbjct: 991  PKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKG 1050

Query: 2099 QDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQG 2158
            Q    GI       G+  E   QG+A    + G   E  + G+     + G+     + G
Sbjct: 1051 QAGPPGI----GIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVG 1106

Query: 2159 VANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVA 2218
                  + G   +   +G+   D I G+  E    G        G   E  + G+     
Sbjct: 1107 YPGSPGLPGEKGD---KGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAG 1163

Query: 2219 AQG 2221
             +G
Sbjct: 1164 EKG 1166



 Score = 52.0 bits (123), Expect = 7e-06
 Identities = 122/672 (18%), Positives = 184/672 (27%), Gaps = 56/672 (8%)

Query: 1600 PDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAA-----HGISKEDAVQGIANE 1654
            P    G+  ++       +    G+      QG   E         G+     + G   E
Sbjct: 697  PKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGE 756

Query: 1655 DAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPV--------QGVA 1706
              + G+       G      +QGI  E    G+   V + GV    P         QG  
Sbjct: 757  KGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPP 816

Query: 1707 NEDAVQGVANEVEVQGVAHED--AVQGIANEDAAHGITNEVAAHGIANEDAAQGIAH--- 1761
                  G+  E    G    D    +G        GIT +    G+  +  A GI     
Sbjct: 817  GLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPG 876

Query: 1762 EDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADG 1821
                 G+            V A G+  E   H        RG   +   +G   +    G
Sbjct: 877  SKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRG---DPGLKGDKGDVGLPG 933

Query: 1822 IPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDA 1881
             P       + +     G   E    G   E  ++G      + G   +    G      
Sbjct: 934  KPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKG 993

Query: 1882 VQGIANEDAAHGIANEDAA------QGIANEDAAQDIANEDAAQGISKEDAVQGIANQDA 1935
              GI+    A G+     +       G   E     I     + G+  +   +G   Q  
Sbjct: 994  DPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAG 1053

Query: 1936 AQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIAN 1995
              GI     + G+  E   QGIA    + G   E  + GI     + G+       G   
Sbjct: 1054 PPGIG----IPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPG 1109

Query: 1996 EDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQA 2055
                 G+  E     +   D   G+  E    G        G   E  + G+        
Sbjct: 1110 SP---GLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGS----- 1161

Query: 2056 IAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVT 2115
             A      G+   G      A G      +G   E     +A    + GI      QG  
Sbjct: 1162 -AGEKGEPGLPGRGFPGFPGAKGD-----KGSKGEVGFPGLA---GSPGIPGSKGEQGFM 1212

Query: 2116 NEVAAQGVANEDAAHGVANE--VAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVE 2173
                 QG      + G A E      G   +    G+   +   G+   D V+G      
Sbjct: 1213 GPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPG 1272

Query: 2174 ------VQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDA 2227
                  V G       QG+     + G+       G       QG       QG+  +  
Sbjct: 1273 WPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQG 1332

Query: 2228 AQGVANEVAVHG 2239
             QGV     + G
Sbjct: 1333 DQGVPGAKGLPG 1344



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 109/628 (17%), Positives = 167/628 (26%), Gaps = 60/628 (9%)

Query: 1623 GIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 1682
            GI  Q    G+  +  A GI       G        G+       G        G+  E 
Sbjct: 852  GITGQSGLPGLPGQQGAPGIP------GFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEK 905

Query: 1683 AVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIT 1742
              HG        G    DP  G+  +    G+  +          +++G   +    G  
Sbjct: 906  GDHGFPGSSGPRG----DP--GLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQI 959

Query: 1743 NEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAA- 1801
              +   G   +    G+  +D   G   +             G++    A  +  P  + 
Sbjct: 960  GPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDP------GISGTPGAPGLPGPKGSV 1013

Query: 1802 -----RGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQ 1856
                  G   E    GI     + G+P +  A G   +    GI     + G+  E   Q
Sbjct: 1014 GGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIG----IPGLRGEKGDQ 1069

Query: 1857 GIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANED 1916
            GIA      G   E    G+       G+     + G      + G+  E   + +   D
Sbjct: 1070 GIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPG---SPGLPGEKGDKGLPGLD 1126

Query: 1917 AAQGISKEDAVQGIANQDAAQGIAKE---DAVQGIANEDAAQGIANEVAAHGIANEDAAQ 1973
               G+  E  + G        G   E   D + G A E    G+       G       +
Sbjct: 1127 GIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGR-GFPGFPGAKGDK 1185

Query: 1974 GIANEDAAQGIAHEDAVQGIANEDAVHGVANEDA--------AHAIAKPDAARGIANEVA 2025
            G   E    G+A    + G   E    G               HA   P   RG   +  
Sbjct: 1186 GSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPG 1245

Query: 2026 AQGIATEDVADGIANEDAAHGVANEDA---AQAIAKPDAAHGIANEGIATEDVADGIAED 2082
              G+       G+   D   G         A  +  P    G             GI   
Sbjct: 1246 LPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQG--------MPGIGGS 1297

Query: 2083 AVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVA 2142
               GIT  +            G       QG+  +   QGV       G       + + 
Sbjct: 1298 P--GITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDII 1355

Query: 2143 NEDAA----QGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANE 2198
              +      +G       QG+      QGV   V + G        G   +    G A  
Sbjct: 1356 KGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGP 1415

Query: 2199 VAAHGVANEDAAQGVANEVAAQGVANED 2226
                G        G+   +   G  + D
Sbjct: 1416 TGPRGFPGPPGPDGLPGSMGPPGTPSVD 1443



 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 138/791 (17%), Positives = 211/791 (26%), Gaps = 81/791 (10%)

Query: 74   VQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVAN 133
            ++G+       G   E  + GV      HG       QG+  E    G+       GV  
Sbjct: 741  LKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPG 800

Query: 134  EDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQG 193
                 G       QG        GI  E    G    D       + A           G
Sbjct: 801  -IGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGA-------QGLPG 852

Query: 194  ISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDA 253
            I+ +  + G+  +  A GI       G        GV       G    V   G+  E  
Sbjct: 853  ITGQSGLPGLPGQQGAPGI------PGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKG 906

Query: 254  VQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAK 313
              G        G        G+  +    G+  +  +       +++G   +    G   
Sbjct: 907  DHGFPGSSGPRG------DPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIG 960

Query: 314  EVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKEVTAHG 373
             +   G   +     +   D   G   +   +G        GI+    A G+        
Sbjct: 961  PIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKG------DPGISGTPGAPGL-------- 1006

Query: 374  VANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEV 433
                   +G V    L G    E     I  P  + G+  +  A G   +    GI    
Sbjct: 1007 ----PGPKGSVGGMGLPG-TPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGI---- 1057

Query: 434  AAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVA 493
                      + G+  E   QGIA    + G   E    GI       G+          
Sbjct: 1058 ---------GIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGL---------- 1098

Query: 494  NKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAH 553
             K +  ++  P  + G+  E   +G+   D   G+  E  + G        G   E  + 
Sbjct: 1099 -KGSPGSVGYP-GSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGS- 1155

Query: 554  AIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANED 613
                 D   G A E    G+       G        G   EV   G+A    + G   E 
Sbjct: 1156 -----DGIPGSAGEKGEPGLPGRGF-PGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQ 1209

Query: 614  AVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVA-----NEDAAQAIAKPD 668
               G        G+      H        +G   +  L G+              +    
Sbjct: 1210 GFMGPPGPQGQPGLPGS-PGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDK 1268

Query: 669  AAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIA 728
               G        G   +   QG+     + GI       G       QG       QGI 
Sbjct: 1269 GNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIK 1328

Query: 729  HEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQ 788
             +   QG+     + G       + +   +P  G+   +   G+     + G   +  V 
Sbjct: 1329 GDQGDQGVPGAKGLPGPPGPPGPYDIIKGEP--GLPGPEGPPGLKGLQGLPGPKGQQGVT 1386

Query: 789  GIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKE- 847
            G+       GI     A G   E    G        G    D + G         V    
Sbjct: 1387 GLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTPSVDHGF 1446

Query: 848  -VTAHGVTNED 857
             VT H  T +D
Sbjct: 1447 LVTRHSQTIDD 1457



 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 196/1099 (17%), Positives = 297/1099 (27%), Gaps = 100/1099 (9%)

Query: 946  QGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVAN-----EVEVQ 1000
            QG   +    GV+      G A +V  +G        G   E   QG+       E    
Sbjct: 225  QGPKGDKGDQGVSGPPGVPGQA-QVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKP 283

Query: 1001 GIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKED 1060
            G   K    G   E  + G   E    G+      QG   E    G    V   G   E 
Sbjct: 284  GPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEK 343

Query: 1061 AVQGIANEDAAQGIANEDAAQGIAHEDA-----VQGIANEDAVHGVAKEVAAHGVANEDP 1115
              +G       +G        G+  +       V G A      G   E    G      
Sbjct: 344  GERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTS- 402

Query: 1116 VQGVANEDAVQGVANEVEVQGVAHE-----DAVQGIANEDAAHGIANEVAAHGIANEDAA 1170
            + G +  D + G        G         +   G   +    GI  +    G   E   
Sbjct: 403  LPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQ 462

Query: 1171 QG----IANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARG 1226
            +G    I + D  +G       QG   E    G        G+   D    +  P    G
Sbjct: 463  KGESCLICDIDGYRG---PPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPG 519

Query: 1227 IANEVAAQGIATEDVAD-------GIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQ 1279
            +  +  A+G   E   D       G        G+     + G      + G      + 
Sbjct: 520  LIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSV 579

Query: 1280 GIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANED 1339
            G+  E    G      ++G        G     PI G   +    G      + G   E 
Sbjct: 580  GLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPI-GDKGQAGFPGGPGSPGLPGPKGEP 638

Query: 1340 AAH-GIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDP---- 1394
                 +     A+G+           +    G      + G        GI    P    
Sbjct: 639  GKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPK 698

Query: 1395 -VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAA-----HGIANEVAAHGIANEDA 1448
             V G+  +    G        G+     VQG   E         G+       G   E  
Sbjct: 699  GVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKG 758

Query: 1449 AQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIAN 1508
            + G+       G      +QGI  E    G+   V + GV       A   P   +G   
Sbjct: 759  SIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPP-GGQGPPG 817

Query: 1509 EVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHG 1568
                 GI  E    G    D   G   +  AQG+       G+  +  + G+  +  A G
Sbjct: 818  LSGPPGIKGEKGFPGFPGLDMP-GPKGDKGAQGLP------GITGQSGLPGLPGQQGAPG 870

Query: 1569 VANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQD 1628
            +      +G +        V           P  A G+  E   H        +G     
Sbjct: 871  IPGFPGSKGEMG-------VMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLK 923

Query: 1629 AAQGIANEVAAHG-ISKED--AVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVH 1685
              +G        G + K D  +++G   +   +G       +G   +    G+  +D   
Sbjct: 924  GDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQA 983

Query: 1686 GVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEV 1745
            G   +    G        G       +G    + + G   E  V GI     + G+  + 
Sbjct: 984  GQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDK 1043

Query: 1746 AAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIA 1805
             A G   +    GI     + G+  E                         K D  +GIA
Sbjct: 1044 GAKGEKGQAGPPGIG----IPGLRGE-------------------------KGD--QGIA 1072

Query: 1806 NEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQ 1865
                + G   E  + GIP    + G+     + G        G+  E   +G+   D I 
Sbjct: 1073 GFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGY---PGSPGLPGEKGDKGLPGLDGIP 1129

Query: 1866 GVANEVEVQGVAHEDAVQGIANEDAAHGI---ANEDAAQGIANEDAAQDIANEDAAQGIS 1922
            GV  E  + G        G   E  + GI   A E    G+               +G  
Sbjct: 1130 GVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGR-GFPGFPGAKGDKGSK 1188

Query: 1923 KEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQ 1982
             E    G+A      G   E    G        G+      H        +G   +    
Sbjct: 1189 GEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGS-PGHATEGPKGDRGPQGQPGLP 1247

Query: 1983 GIAHEDAVQGIANEDAVHG 2001
            G+       G+   D V G
Sbjct: 1248 GLPGPMGPPGLPGIDGVKG 1266



 Score = 35.0 bits (79), Expect = 0.88
 Identities = 82/429 (19%), Positives = 115/429 (26%), Gaps = 73/429 (17%)

Query: 67   GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126
            G+  E   QG+A    + G   E  + G+     + G+     + G      + G+  E 
Sbjct: 1061 GLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPG---SPGLPGEK 1117

Query: 127  AVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGI---ANEDAAQDI------- 176
              +G+   D + GV  E  + G        G   E  + GI   A E     +       
Sbjct: 1118 GDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPG 1177

Query: 177  ---AKED-------------AAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPV-- 218
               AK D              +  I      QG       QG      + G A E P   
Sbjct: 1178 FPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGD 1237

Query: 219  ---------------QGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAA 263
                            G      + GV  +    G      V G   +   QG+     +
Sbjct: 1238 RGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGS 1297

Query: 264  HGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANE-------------DAVHG 310
             GIT      G       QG       QGI  +   QG+                D + G
Sbjct: 1298 PGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKG 1357

Query: 311  VAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKEVT 370
                    G         +  P    G+   V   G        GI   D A G   E+ 
Sbjct: 1358 EPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPG------PPGIPGFDGAPGQKGEMG 1411

Query: 371  AHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIA 430
              G        G    D L G +           P   HG    V  H    +D      
Sbjct: 1412 PAGPTGPRGFPGPPGPDGLPGSMGPP------GTPSVDHGFL--VTRHSQTIDDPQCPSG 1463

Query: 431  NEVAAHGIS 439
             ++  HG S
Sbjct: 1464 TKILYHGYS 1472


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score = 63.9 bits (154), Expect = 2e-09
 Identities = 179/1031 (17%), Positives = 288/1031 (27%), Gaps = 57/1031 (5%)

Query: 1225 RGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKE 1284
            RG   E+   G+  E    G        G    V A G+  E   +G   E   +G+   
Sbjct: 550  RGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGL--- 606

Query: 1285 DAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGI 1344
            D   G   +   QG      V G   E    G A    V G   +   +G+  E  A G 
Sbjct: 607  DGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQ--EGLKGEQGAPGP 664

Query: 1345 ANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAV 1404
                 A G             D   G+     ++G   +    GI     +QG      V
Sbjct: 665  RGHQGAPGPPGARGPIGPEGRDGPPGLQ---GLRGKKGDMGPPGIPGLLGLQGPPGPPGV 721

Query: 1405 QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHE 1464
             G        G+  E    G        G   +   +G       +G   E    G+  +
Sbjct: 722  PGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGK 781

Query: 1465 DAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGI 1524
              ++G   E  + G   E    G+        +      +G   E+   G+  +    G 
Sbjct: 782  PGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGE 841

Query: 1525 ANEDAAHGVANEVAA----------QGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDA 1574
            A      G+    +           QG   E    G+  E  +QG   E+   G      
Sbjct: 842  AGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPG 901

Query: 1575 VQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIA 1634
             +G            N  A   +  P  + G    V A  +       G   +  A G  
Sbjct: 902  AKGQEGAHGAPGAAGNPGAPGHVGAPGPS-GPPGSVGAPGLRGTPGKDGERGEKGAAGEE 960

Query: 1635 NEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAK--EVA 1692
                  G   +    G+           +D   G+     + G     A  G  +  E  
Sbjct: 961  GSPGPVGPRGDPGAPGLPGPPGK----GKDGEPGLRGSPGLPGPLGTKAACGKVRGSENC 1016

Query: 1693 AHG---VANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHG 1749
            A G   V  +    G+      +G    + V G        G      + G+       G
Sbjct: 1017 ALGGQCVKGDRGAPGIPGSPGSRGDPG-IGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQG 1075

Query: 1750 IANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVA 1809
             A  D A G   E   +G   +  + S+      + +A +        P    G+     
Sbjct: 1076 PAGRDGAPGNPGE---RGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKG 1132

Query: 1810 AQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVAN 1869
             +G+       G P  +   G   E    G+       GIA    +QG       +G   
Sbjct: 1133 DKGVP------GKPGREGTEGKKGEAGPPGLP---GPPGIAGPQGSQG------ERGADG 1177

Query: 1870 EVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQG 1929
            EV  +G      V G        G    D   G A     Q    ++   G      + G
Sbjct: 1178 EVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPG 1237

Query: 1930 IANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDA 1989
            I  ++  +G    D   G   E    G        G       +G   +  A G   E  
Sbjct: 1238 IPGEEGKEG---RDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESG 1294

Query: 1990 VQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVAN 2049
              G+  ++ + G   +        P   RG   +  + G   E    G   +  + G   
Sbjct: 1295 AMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENG 1354

Query: 2050 EDAAQAIAKPDAAHGIANE-GIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKE 2108
                     P    G   E G+  ++   G  +    G   E     I       G   +
Sbjct: 1355 SPGLPGFLGPRGPPGEPGEKGVPGKEGVPG--KPGEPGFKGERGDPGIKGDKGPPGGKGQ 1412

Query: 2109 DAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGV 2168
                G+       G+       G    V   G   +    G+  E  +         + +
Sbjct: 1413 PGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEEL 1472

Query: 2169 ANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAA 2228
              ++E + +A+  A    A   ++QG        G   +D   G A  +   G   +   
Sbjct: 1473 GKQLETR-LAYLLAQMPPAYMKSSQG---RPGPPGPPGKDGLPGRAGPMGEPGRPGQGGL 1528

Query: 2229 QGVANEVAVHG 2239
            +G +  +   G
Sbjct: 1529 EGPSGPIGPKG 1539



 Score = 62.4 bits (150), Expect = 5e-09
 Identities = 142/794 (17%), Positives = 224/794 (28%), Gaps = 58/794 (7%)

Query: 946  QGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHK 1005
            QG        G      A+G        G      + G   +    G+   + +QG    
Sbjct: 659  QGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGP 718

Query: 1006 DAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGI 1065
              + G      + G+  E+   G        G   +D   G        G   E    G+
Sbjct: 719  PGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGL 778

Query: 1066 ANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAV 1125
              +   +G   E    G   E    G+       GV  E    G   E  + G+  +   
Sbjct: 779  PGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGE 838

Query: 1126 QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHE 1185
            +G A      G A    + G  +    H         G   E    G+  E   QG   E
Sbjct: 839  KGEA------GPAGPPGLPGTTSLFTPH--PRMPGEQGPKGEKGDPGLPGEPGLQGRPGE 890

Query: 1186 DAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGI 1245
               QG        G      A G A    A          G    V A G+      DG 
Sbjct: 891  LGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGE 950

Query: 1246 ANEDAAHGVANEVAAHGISKEDAVQGI-----ANEDAAQGIAKEDAVQGIANEDAAQGIA 1300
              E  A G        G   +    G+       +D   G+     + G     AA G  
Sbjct: 951  RGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKV 1010

Query: 1301 KEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQ 1360
            +      +      Q V  +    G+      +G    D   G+A      G   +  + 
Sbjct: 1011 RGSENCALGG----QCVKGDRGAPGIPGSPGSRG----DPGIGVAGPPGPSGPPGDKGS- 1061

Query: 1361 DIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHE- 1419
                   ++G+      QG A  D A G   E   +G   +  +  + +  ++  +A + 
Sbjct: 1062 -----PGSRGLPGFPGPQGPAGRDGAPGNPGE---RGPPGKPGLSSLLSPGDINLLAKDV 1113

Query: 1420 --DAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVH 1477
              D   G        G   +    G    +  +G   E    G+     + G        
Sbjct: 1114 CNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGER 1173

Query: 1478 GVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEV 1537
            G   EV   G    D  H         G+   +   G      ADGIA      G A   
Sbjct: 1174 GADGEVGQKG----DQGHP--------GVPGFMGPPGNPGPPGADGIA------GAAGPP 1215

Query: 1538 AAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAI 1597
              QG   +    G      + G+  E    G   +    G   +     +   E A    
Sbjct: 1216 GIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGA---- 1271

Query: 1598 AKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAA 1657
              P    G   +  A     +  A G+  Q+   G   +    G       +G   ++ +
Sbjct: 1272 RGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGS 1331

Query: 1658 QGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANE 1717
             G   E    G   +   +G   E+   G+   +   G   E   +GV  ++ V G   E
Sbjct: 1332 PGSPGEPGPSGTPGQ---KGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGE 1388

Query: 1718 VEVQGVAHEDAVQG 1731
               +G   +  ++G
Sbjct: 1389 PGFKGERGDPGIKG 1402



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 159/876 (18%), Positives = 234/876 (26%), Gaps = 83/876 (9%)

Query: 410  GIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHED 469
            G+  EV   G        G    V A G+  E   +G   E   +G+   D   G   + 
Sbjct: 560  GLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGL---DGFPGKPGDT 616

Query: 470  AVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQ-GIATEDVADGI 528
              QG      V G   E    G            P    G+   V  Q G+  E  A G 
Sbjct: 617  GQQGRPGPSGVAGPQGEKGDVG------------PAGPPGVPGSVVQQEGLKGEQGAPGP 664

Query: 529  ANEDAVHGVANEVAAHGVANEDAAHAIA-----KPDAAH-GIANEVATQGIATEDVADGI 582
                   G        G    D    +      K D    GI   +  QG        G 
Sbjct: 665  RGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGP 724

Query: 583  ANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAV 642
                 + G+  E+   G        G   +D  +G       +G   E    G+  +  +
Sbjct: 725  PGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGL 784

Query: 643  QGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAN 702
            +G + E  L G    +  A     P    G+  E    G   E    G+  +   +G A 
Sbjct: 785  RGEIGEQGLAGRPGEKGEAGLPGAPGFP-GVRGEKGDQGEKGELGLPGLKGDRGEKGEAG 843

Query: 703  EVAAHGI-------------------SKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVH 743
                 G+                     E    G+  E   QG   E   QG        
Sbjct: 844  PAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAK 903

Query: 744  GVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEV 803
            G      A G A      G        G    V   G+       G   E  A G     
Sbjct: 904  GQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSP 963

Query: 804  AAHGVANEDAAQGVAN-----EDAAQGVANEDAVHGVANEDAAQGVAK--EVTAHG---V 853
               G   +  A G+       +D   G+     + G     AA G  +  E  A G   V
Sbjct: 964  GPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCV 1023

Query: 854  TNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANE-------GVANEVAAQGIAT 906
              +    G+       G     D    +A P    G   +       G+      QG A 
Sbjct: 1024 KGDRGAPGIPGSPGSRG-----DPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAG 1078

Query: 907  EDVADGI-------AKDAAHGITKEEAAQAIAKQ---DAAHSITNEDAAQGVANEDAAHG 956
             D A G         K     +        +AK    D            G   +    G
Sbjct: 1079 RDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPG 1138

Query: 957  VANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDA 1016
                +  +G   E    G+     + G       +G   EV  +G      + G      
Sbjct: 1139 KPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPG 1198

Query: 1017 ------AHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDA 1070
                  A GIA      GI      +G        G+       G    D   G   E  
Sbjct: 1199 NPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPG 1258

Query: 1071 AQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVAN 1130
              G       +G       +G   +    G   E  A G+  ++ + G   +    G   
Sbjct: 1259 KAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQG 1318

Query: 1131 EVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQG 1190
                +G   ++   G   E    G   +  + G   E+ + G+      +G   E   +G
Sbjct: 1319 PQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKG---ENGSPGLPGFLGPRGPPGEPGEKG 1375

Query: 1191 IANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARG 1226
            +  ++ V G   E    G   +        P   +G
Sbjct: 1376 VPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKG 1411



 Score = 58.9 bits (141), Expect = 6e-08
 Identities = 155/813 (19%), Positives = 231/813 (28%), Gaps = 84/813 (10%)

Query: 76   GVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANED 135
            G+  EV  +G        G    V A G+  E   +G   E   +G+   D   G   + 
Sbjct: 560  GLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGL---DGFPGKPGDT 616

Query: 136  AVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQGIS 195
              QG      V G   E    G A      G         + +++  +        QG  
Sbjct: 617  GQQGRPGPSGVAGPQGEKGDVGPAGPPGVPG--------SVVQQEGLK------GEQGAP 662

Query: 196  KEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQ 255
                 QG      A+G    +   G      ++G   +    G+   + +QG      V 
Sbjct: 663  GPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVP 722

Query: 256  GIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEV 315
            G      + G+  E+   G        G   +D   G       +G   E    G+    
Sbjct: 723  GPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLP--- 779

Query: 316  AAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKEVTAHGVA 375
                           KP    G+  E+  QG+A      G A    A G        GV 
Sbjct: 780  --------------GKP----GLRGEIGEQGLAGRPGEKGEAGLPGAPGFP------GVR 815

Query: 376  NEDAVQGVVNEDALHGVVAN--EDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEV 433
             E   QG   E  L G+  +  E      A P    G  +    H        QG   E 
Sbjct: 816  GEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPH--PRMPGEQGPKGEK 873

Query: 434  AAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVA 493
               G+  E  +QG   E   QG      A+G        G A      G    V A G +
Sbjct: 874  GDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPG---HVGAPGPS 930

Query: 494  NKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAH 553
                +          G   E   +G A E+ + G        G        G   +    
Sbjct: 931  GPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPG 990

Query: 554  AIAKPDAAHGIANEVATQGI-ATEDVADG---IANEDAAHGVANEVAVHGVAIEDAVQGV 609
                P     +  + A   +  +E+ A G   +  +  A G+       G    D   GV
Sbjct: 991  LRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRG----DPGIGV 1046

Query: 610  ANEDAVHGVANEDAA---QGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAK 666
            A      G   +  +   +G+       G A  D   G   E    G    +    ++  
Sbjct: 1047 AGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPG----KPGLSSLLS 1102

Query: 667  PDAAHGIANEVAAH---------GIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQG 717
            P   + +A +V            G+      +G+  +   +G   +    G        G
Sbjct: 1103 PGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPG 1162

Query: 718  IANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVE 777
            IA    +QG    D   G   +    GV   +   G        G+A      G A    
Sbjct: 1163 IAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIA------GAAGPPG 1216

Query: 778  VQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVAN 837
            +QG   ++   G        GI  E    G    D   G   E    G        G   
Sbjct: 1217 IQGSPGKEGPPGPQGPSGLPGIPGE---EGKEGRDGKPGPPGEPGKAGEPGLPGPEGARG 1273

Query: 838  EDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHG 870
                +G   +  A G   E    G+  +E L G
Sbjct: 1274 PPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPG 1306



 Score = 58.2 bits (139), Expect = 1e-07
 Identities = 139/779 (17%), Positives = 205/779 (26%), Gaps = 36/779 (4%)

Query: 75   QGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANE 134
            QG       QG      A G        G       +G   ++   G+     +QG    
Sbjct: 659  QGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGP 718

Query: 135  DAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQGI 194
              V G        G+  E    G        G   +D           +    E    G+
Sbjct: 719  PGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGL 778

Query: 195  SKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAV 254
              +  ++G   E    G   E    G+       GV  E   QG   E+ + G+  +   
Sbjct: 779  PGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGE 838

Query: 255  QGIANEDAAHGITNEVA----------AHGIANEDAAQGIANEDAAQGIAHEDAVQGIAN 304
            +G A      G+    +            G   E    G+  E   QG   E   QG   
Sbjct: 839  KGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTG 898

Query: 305  EDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHG 364
                 G      A G A    A          G    V   G+      DG   E  A G
Sbjct: 899  PPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAG 958

Query: 365  VAKEVTAHGVANEDAVQGVV--------NEDALHGVVANEDAAQAIAKPDAAHGIAN-EV 415
                    G   +    G+          E  L G           A      G  N  +
Sbjct: 959  EEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCAL 1018

Query: 416  AAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIA 475
                +  +  A GI     + G      V G        G      ++G+      QG A
Sbjct: 1019 GGQCVKGDRGAPGIPGSPGSRG-DPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPA 1077

Query: 476  NEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVH 535
              D   G   E    G   K    ++  P     +A +V            G+       
Sbjct: 1078 GRDGAPGNPGE---RGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDK 1134

Query: 536  GVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEV 595
            GV  +    G   +      A P    G       QG   E  ADG   E    G     
Sbjct: 1135 GVPGKPGREGTEGKKGE---AGPPGLPGPPGIAGPQGSQGERGADG---EVGQKGDQGHP 1188

Query: 596  AVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVV 655
             V G        G    D + G A     QG   +    G      + G+  E+   G  
Sbjct: 1189 GVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEG-- 1246

Query: 656  ANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAV 715
               D            G        G       +G   +  A G   E  A G+  +   
Sbjct: 1247 --RDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQ--- 1301

Query: 716  QGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANE 775
            +G+  +D   G       QG       +G        G +     +G   E+   G+   
Sbjct: 1302 EGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGF 1361

Query: 776  VEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHG 834
            +  +G   E   +G+  ++   G   E    G   +   +G       +G   +  + G
Sbjct: 1362 LGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPG 1420



 Score = 55.1 bits (131), Expect = 8e-07
 Identities = 161/878 (18%), Positives = 238/878 (27%), Gaps = 70/878 (7%)

Query: 1408 ANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIA----NEDAAQGIAH 1463
            A E    GVA    + G   +  A G    V A G   E    GI      E   +G   
Sbjct: 480  AGEKGEMGVAGPMGLPGPKGDIGAIG---PVGAPGPKGEKGDVGIGPFGQGEKGEKGSLG 536

Query: 1464 EDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADG 1523
                 G      + G   E+   G+  E        P    G    V   G+  E    G
Sbjct: 537  LPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKG 596

Query: 1524 IANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQG-VVNED 1582
               E    G+       G   +    G +     QG   +V   G A    V G VV ++
Sbjct: 597  TRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDV---GPAGPPGVPGSVVQQE 653

Query: 1583 ALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGI 1642
             L          Q    P    G      A      +   G       +G   ++   GI
Sbjct: 654  GLKG-------EQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGI 706

Query: 1643 SKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPV 1702
                 +QG        G      + G+  E    G        G   +   +G       
Sbjct: 707  PGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGT 766

Query: 1703 QGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHE 1762
            +G   E    G+  +  ++G   E  + G   E    G+       G+  E   QG   E
Sbjct: 767  KGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGE 826

Query: 1763 DAVQGIANEDAVHSVAKEVAAHGVANEDAAHAI-AKPDAARGIANEVAAQGIATEDVADG 1821
              + G+  +      A      G+    +      +    +G   E    G+  E    G
Sbjct: 827  LGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQG 886

Query: 1822 IPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDA 1881
             P E    G      A G        G A    A G        G    V   G+     
Sbjct: 887  RPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPG 946

Query: 1882 VQGIANEDAAHGIANEDAAQGIANEDAAQDIAN-----EDAAQGISKEDAVQGIANQDAA 1936
              G   E  A G        G   +  A  +       +D   G+     + G     AA
Sbjct: 947  KDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAA 1006

Query: 1937 QGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANE 1996
             G  +        +E+ A G         +  +  A GI     ++G    D   G+A  
Sbjct: 1007 CGKVR-------GSENCALG------GQCVKGDRGAPGIPGSPGSRG----DPGIGVAGP 1049

Query: 1997 DAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAI 2056
                G   +  +        +RG+      QG A  D A G   E    G   +    ++
Sbjct: 1050 PGPSGPPGDKGS------PGSRGLPGFPGPQGPAGRDGAPGNPGE---RGPPGKPGLSSL 1100

Query: 2057 AKPD----AAHGIANEGIATEDVADGI----AEDAVQGITNEEAAQAIAKQDAAHGITKE 2108
              P      A  + N+         G+     +  V G    E  +    +    G+   
Sbjct: 1101 LSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLP-- 1158

Query: 2109 DAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGV 2168
                G+     +QG        G   EV   G        G        G    D + G 
Sbjct: 1159 -GPPGIAGPQGSQG------ERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGA 1211

Query: 2169 ANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAA 2228
            A    +QG   K+   G        G+  E    G    D   G   E    G       
Sbjct: 1212 AGPPGIQGSPGKEGPPGPQGPSGLPGIPGE---EGKEGRDGKPGPPGEPGKAGEPGLPGP 1268

Query: 2229 QGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHG 2266
            +G        G   +  A     E  A G+  ++   G
Sbjct: 1269 EGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPG 1306



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 170/937 (18%), Positives = 262/937 (27%), Gaps = 75/937 (8%)

Query: 274  GIANEDAAQGIANEDAA---QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIA 330
            G    D ++G+  E       G+  E  ++G      + G    V A G+  E       
Sbjct: 539  GPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGE------- 591

Query: 331  KPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALH 390
                      E  T+G   E   DG   +    G        GVA     +G V      
Sbjct: 592  --------RGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPP 643

Query: 391  GVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANE 450
            GV  +    + +     A G      A G      A+G        G      ++G   +
Sbjct: 644  GVPGSVVQQEGLKGEQGAPGPRGHQGAPG---PPGARGPIGPEGRDGPPGLQGLRGKKGD 700

Query: 451  DAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGI 510
                GI      QG      V G        G+  E+   G             D   G 
Sbjct: 701  MGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGP 760

Query: 511  ANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVAT 570
                  +G   E   DG+  +  + G   E    G   E     +       G+  E   
Sbjct: 761  PGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGD 820

Query: 571  QGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAV----------QGVANEDAVHGVAN 620
            QG   E    G+  +    G A      G+    ++          QG   E    G+  
Sbjct: 821  QGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPG 880

Query: 621  EDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAH 680
            E   QG   E+   G       +G        G   N  A   +  P  + G    V A 
Sbjct: 881  EPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPS-GPPGSVGAP 939

Query: 681  GIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANED 740
            G+       G   E  A G        G   +    G+           +D   G+    
Sbjct: 940  GLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKG----KDGEPGLRGSP 995

Query: 741  AVHGVAKEVAAHGVANEDPVQGVANEDVV-QGVANEVEVQGIAHEDAVQGIANEDAAHGI 799
             + G     AA G      V+G  N  +  Q V  +    GI      +G    D   G+
Sbjct: 996  GLPGPLGTKAACG-----KVRGSENCALGGQCVKGDRGAPGIPGSPGSRG----DPGIGV 1046

Query: 800  ANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAV 859
            A      G   +  + G      ++G+       G A  D A G   E    G     ++
Sbjct: 1047 AGPPGPSGPPGDKGSPG------SRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSL 1100

Query: 860  QGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAH 919
                +   L   V N+        P       ++GV  +   +G  TE       K    
Sbjct: 1101 LSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREG--TE------GKKGEA 1152

Query: 920  GITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANED 979
            G         IA    +      D   G   +    GV       G      A G+A   
Sbjct: 1153 GPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIA--- 1209

Query: 980  AVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIA 1039
               G A    +QG   +    G      + GI  E+   G   +    G   +    G+ 
Sbjct: 1210 ---GAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLP 1266

Query: 1040 NEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANE------DAAQGIAHEDAVQGIA 1093
              + A+G        G + +    G   E  A G+  +      D   G       QG  
Sbjct: 1267 GPEGARG---PPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPR 1323

Query: 1094 NEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAH 1153
                 +G        G +     +G   E+   G+   +  +G   E   +G+  ++   
Sbjct: 1324 GPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVP 1383

Query: 1154 GIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQG 1190
            G   E    G   +   +G       +G   +  + G
Sbjct: 1384 GKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPG 1420


>gi|5803080 macrophage receptor with collagenous structure [Homo
            sapiens]
          Length = 520

 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 58/290 (20%), Positives = 84/290 (28%), Gaps = 6/290 (2%)

Query: 1243 DGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKE 1302
            D          +  E  A G+       G+       G   E   +G    D A G +  
Sbjct: 135  DNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGP 194

Query: 1303 DPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDI 1362
                GV  E  +QG       QG       QG        G+       G   E     +
Sbjct: 195  QGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGL 254

Query: 1363 ANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAV 1422
                  +G+  +  V G      ++G        G+A     +G   +  +QGV      
Sbjct: 255  PGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGA 314

Query: 1423 QGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE 1482
             G        G A      G+     + G      ++G       QG   E  V G A  
Sbjct: 315  VGHPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPA-- 372

Query: 1483 VAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHG 1532
                GV  E  +  +A P  A G A +   QG+       G+  E    G
Sbjct: 373  ----GVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERG 418



 Score = 58.5 bits (140), Expect = 7e-08
 Identities = 67/324 (20%), Positives = 100/324 (30%), Gaps = 30/324 (9%)

Query: 1723 VAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVA 1782
            V+HE  +Q + N       T       I  E  A G+       G+           E  
Sbjct: 125  VSHEHLLQRVDN------FTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKG 178

Query: 1783 AHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISK 1842
            A G    D A   + P    G+  E   QG        G P +  A G        G   
Sbjct: 179  AKGAMGRDGATGPSGPQGPPGVKGEAGLQG------PQGAPGKQGATGTPGPQGEKGSKG 232

Query: 1843 EDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQG 1902
            +  + G   E   +G   +  + G   +  ++G A      G+     A G      ++G
Sbjct: 233  DGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKGDA------GVMGPPGAQG------SKG 280

Query: 1903 IANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVA 1962
                     +A    A+G   +  +QG+     A G        G A      G+     
Sbjct: 281  DFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPG 340

Query: 1963 AHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIAN 2022
            + G      ++G       QG   E  V G A      GV  E  +  +A P  A G A 
Sbjct: 341  SPGATGLKGSKGDTGLQGQQGRKGESGVPGPA------GVKGEQGSPGLAGPKGAPGQAG 394

Query: 2023 EVAAQGIATEDVADGIANEDAAHG 2046
            +   QG+       G+  E    G
Sbjct: 395  QKGDQGVKGSSGEQGVKGEKGERG 418



 Score = 58.2 bits (139), Expect = 1e-07
 Identities = 54/273 (19%), Positives = 79/273 (28%), Gaps = 3/273 (1%)

Query: 939  ITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVE 998
            I  E  A G+     A G+       G   E  A+G    D   G +      GV  E  
Sbjct: 146  IKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAG 205

Query: 999  VQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISK 1058
            +QG       QG        G        G+       G   E    G+       G+  
Sbjct: 206  LQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKG 265

Query: 1059 EDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV---AKEVAAHGVANEDP 1115
            +  V G      ++G        G+A     +G   +  + GV      V   G   E  
Sbjct: 266  DAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPG 325

Query: 1116 VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIAN 1175
              G      + G        G+       G+  +    G +      G+  E  + G+A 
Sbjct: 326  SAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPAGVKGEQGSPGLAG 385

Query: 1176 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHG 1208
               A G A +   QG+       GV  E    G
Sbjct: 386  PKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERG 418



 Score = 56.6 bits (135), Expect = 3e-07
 Identities = 80/378 (21%), Positives = 120/378 (31%), Gaps = 26/378 (6%)

Query: 1936 AQGIAKEDAVQG------IANEDAAQGIANEVAAHG---IANEDAAQGIANEDAAQGIAH 1986
            AQG ++   +Q       +++E   Q + N     G   I  E  A G+     A G+  
Sbjct: 107  AQGASRLQVLQAQLTWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPG 166

Query: 1987 EDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHG 2046
                 G   E    G    D A   + P    G+  E   QG        G        G
Sbjct: 167  APGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQG 226

Query: 2047 VANEDAAQAIAKPDAAHGIANE----GIATEDVADGIAEDA-VQGITNEEAAQAIAKQDA 2101
                     +  P    G   E    G+       G+  DA V G    + ++    +  
Sbjct: 227  EKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPG 286

Query: 2102 AHGITKEDAAQGVTNEVAAQGVANEDAA---HGVANEVAAHGVANEDAAQGVANEVAAQG 2158
              G+     A+G   +   QGV     A    G   E  + G        G      A G
Sbjct: 287  PPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPGATG 346

Query: 2159 VANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVA 2218
            +       G+  +   +G +      G+  E  + G+A    A G A +   QGV     
Sbjct: 347  LKGSKGDTGLQGQQGRKGESGVPGPAGVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSG 406

Query: 2219 AQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAV----- 2273
             QGV  E   +G  N V+V  V + +  R         G   +D      N DA+     
Sbjct: 407  EQGVKGEKGERG-ENSVSVRIVGSSNRGRAEVYYSGTWGTICDDEWQ---NSDAIVFCRM 462

Query: 2274 HGIANEDAVYDIANDTVQ 2291
             G +   A+Y +   T Q
Sbjct: 463  LGYSKGRALYKVGAGTGQ 480



 Score = 56.2 bits (134), Expect = 4e-07
 Identities = 68/321 (21%), Positives = 97/321 (30%), Gaps = 15/321 (4%)

Query: 1167 EDAAQGIANEDAAQG------IAHEDAVQGIANEDAVHGVAK---EVAAHGVANEDAAHA 1217
            E  AQG +     Q       ++HE  +Q + N     G+ +   E  A G+     A  
Sbjct: 104  EHLAQGASRLQVLQAQLTWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMG 163

Query: 1218 IAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDA 1277
            +       G   E  A+G    D A G +      GV  E    G       QG      
Sbjct: 164  MPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPG 223

Query: 1278 AQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIAN 1337
             QG        G+       G   E    G+      +G+  +  V G       +G   
Sbjct: 224  PQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFG 283

Query: 1338 EDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQG 1397
                 G+A    A+G   +   Q +     A G        G A      G+       G
Sbjct: 284  RPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPG 343

Query: 1398 VANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDA 1457
                   +G       QG   E  V G A      G+  E  + G+A    A G A +  
Sbjct: 344  ATGLKGSKGDTGLQGQQGRKGESGVPGPA------GVKGEQGSPGLAGPKGAPGQAGQKG 397

Query: 1458 AQGIAHEDAVQGIANEDAVHG 1478
             QG+      QG+  E    G
Sbjct: 398  DQGVKGSSGEQGVKGEKGERG 418



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 67/324 (20%), Positives = 93/324 (28%), Gaps = 12/324 (3%)

Query: 1032 EDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG---IANEDAAQGIAHEDA 1088
            E  AQG +     Q     V    +S E  +Q + N     G   I  E  A G+     
Sbjct: 104  EHLAQGASRLQVLQAQLTWVR---VSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKG 160

Query: 1089 VQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIAN 1148
              G+       G   E  A G    D   G +      GV  E  +QG       QG   
Sbjct: 161  AMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATG 220

Query: 1149 EDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHG 1208
                 G        G+       G   E    G+      +G+  +  V G      + G
Sbjct: 221  TPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKG 280

Query: 1209 VANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDA 1268
                     +A    A+G   +   QG+     A G        G A      G+     
Sbjct: 281  DFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPG 340

Query: 1269 VQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAH 1328
              G      ++G       QG   E    G A      GV  E    G+A      G A 
Sbjct: 341  SPGATGLKGSKGDTGLQGQQGRKGESGVPGPA------GVKGEQGSPGLAGPKGAPGQAG 394

Query: 1329 EDAVQGIANEDAAHGIANEDAAQG 1352
            +   QG+       G+  E   +G
Sbjct: 395  QKGDQGVKGSSGEQGVKGEKGERG 418



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 57/279 (20%), Positives = 80/279 (28%), Gaps = 6/279 (2%)

Query: 921  ITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDA 980
            I  E+ A  +     A  +       G   E  A G    D A G +      GV  E  
Sbjct: 146  IKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAG 205

Query: 981  VHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIAN 1040
            + G       QG       QG        G+       G   E    G+      +G+  
Sbjct: 206  LQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKG 265

Query: 1041 EDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHG 1100
            +    G      + G        G+A    A+G   +   QG+       G        G
Sbjct: 266  DAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPG 325

Query: 1101 VAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVA 1160
             A      G+       G       +G       QG   E  V G A      G+  E  
Sbjct: 326  SAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPA------GVKGEQG 379

Query: 1161 AHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHG 1199
            + G+A    A G A +   QG+      QG+  E    G
Sbjct: 380  SPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERG 418



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 61/297 (20%), Positives = 86/297 (28%), Gaps = 24/297 (8%)

Query: 68  ITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDA 127
           I  E    G+     A G+       G   E  A G    D A G +      GV  E  
Sbjct: 146 IKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAG 205

Query: 128 VQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIAN 187
           +QG       QG       QG        G+       G   E    D+    +  D   
Sbjct: 206 LQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKG--DLGLPGSKGD--- 260

Query: 188 EDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQG 247
               +G+  +  V G      ++G        G+A     +G   +  +QGV       G
Sbjct: 261 ----RGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVG 316

Query: 248 VAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDA 307
                   G A      G+     + G      ++G       QG   E  V G A    
Sbjct: 317 HPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPA---- 372

Query: 308 VHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHG 364
                      GV  E  +  +A P  A G A +   QG+       G+  E    G
Sbjct: 373 -----------GVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERG 418



 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 58/279 (20%), Positives = 82/279 (29%), Gaps = 6/279 (2%)

Query: 1651 IANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDA 1710
            I  E  A G+     A G+       G   E    G      A G +      GV  E  
Sbjct: 146  IKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAG 205

Query: 1711 VQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIAN 1770
            +QG       QG       QG        G+       G   E    G+      +G+  
Sbjct: 206  LQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKG 265

Query: 1771 EDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHG 1830
            +  V        + G         +A    A+G   +   QG+     A G P      G
Sbjct: 266  DAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPG 325

Query: 1831 VANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDA 1890
             A      G+       G      ++G       QG   E  V G A      G+  E  
Sbjct: 326  SAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPA------GVKGEQG 379

Query: 1891 AHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQG 1929
            + G+A    A G A +   Q +      QG+  E   +G
Sbjct: 380  SPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERG 418



 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 57/300 (19%), Positives = 89/300 (29%), Gaps = 9/300 (3%)

Query: 1002 IAHKDAIQGIANEDAAHG---IANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISK 1058
            ++H+  +Q + N     G   I  E  A G+     A G+       G   E  A G   
Sbjct: 125  VSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMG 184

Query: 1059 EDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQG 1118
             D   G +      G+  E   QG       QG        G        G+       G
Sbjct: 185  RDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETG 244

Query: 1119 VANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDA 1178
               E    G+      +G+  +  V G      + G        G+A    A+G   +  
Sbjct: 245  TKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPG 304

Query: 1179 AQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIAT 1238
             QG+       G        G A      G+     +        A G+       G+  
Sbjct: 305  LQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGS------PGATGLKGSKGDTGLQG 358

Query: 1239 EDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQG 1298
            +    G +      GV  E  + G++      G A +   QG+      QG+  E   +G
Sbjct: 359  QQGRKGESGVPGPAGVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERG 418



 Score = 52.4 bits (124), Expect = 5e-06
 Identities = 68/343 (19%), Positives = 101/343 (29%), Gaps = 13/343 (3%)

Query: 1137 VAHEDAVQGIANEDAAHG---IANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIAN 1193
            V+HE  +Q + N     G   I  E  A G+     A G+       G   E   +G   
Sbjct: 125  VSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMG 184

Query: 1194 EDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHG 1253
             D   G +      GV  E            +G       QG        G+       G
Sbjct: 185  RDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETG 244

Query: 1254 VANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDP 1313
               E    G+      +G+  +    G       +G        G+A     +G   +  
Sbjct: 245  TKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPG 304

Query: 1314 IQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISK 1373
            +QGV       G        G A      G+     + G      ++        QG   
Sbjct: 305  LQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKG 364

Query: 1374 EDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHG 1433
            E  V G A      G+  E    G+A      G A +   QGV      QG+  E    G
Sbjct: 365  ESGVPGPA------GVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERG 418

Query: 1434 IANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAV 1476
              N V+   + + +  +         G   +D  Q   N DA+
Sbjct: 419  -ENSVSVRIVGSSNRGRAEVYYSGTWGTICDDEWQ---NSDAI 457



 Score = 51.6 bits (122), Expect = 9e-06
 Identities = 89/411 (21%), Positives = 136/411 (33%), Gaps = 34/411 (8%)

Query: 528 IANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADG------ 581
           I  ED +     + A H +A E     + KP   +G+   +A   I    +  G      
Sbjct: 6   ILKEDELLSETQQAAFHQIAMEPFEINVPKPKRRNGVNFSLAVVVIYLILLTAGAGLLVV 65

Query: 582 -IANEDAAHGVANEVAVHG-VAIEDAVQGVANEDAVHGVANEDAAQGIAK------EVTA 633
            + N  A   V     ++  +A ED+      + A  G   E  AQG ++      ++T 
Sbjct: 66  QVLNLQARLRVLEMYFLNDTLAAEDSPSFSLLQSAHPG---EHLAQGASRLQVLQAQLTW 122

Query: 634 HGVANEDAVQGVVNEDALHGV--VANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGI 691
             V++E  +Q V N     G+  +  E  A  +     A G+       G   E  A+G 
Sbjct: 123 VRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGA 182

Query: 692 ANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAA 751
              D A G +      G+  E  +QG       QG       QG        G+      
Sbjct: 183 MGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGE 242

Query: 752 HGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANE 811
            G   E    G+      +G+  +  V G       +G        G+A    A G   +
Sbjct: 243 TGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQ 302

Query: 812 DAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVT------NEDAVQGVVNE 865
              QGV     A G        G A      G+     + G T       +  +QG    
Sbjct: 303 PGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGR 362

Query: 866 EALHGV-----VANEDAAQAIAKPDAAHGIA----NEGVANEVAAQGIATE 907
           +   GV     V  E  +  +A P  A G A    ++GV      QG+  E
Sbjct: 363 KGESGVPGPAGVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGE 413



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 50/268 (18%), Positives = 78/268 (29%), Gaps = 3/268 (1%)

Query: 1804 IANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDP 1863
            I  E  A G+     A G+P      G   E  A G    D   G +      G+  E  
Sbjct: 146  IKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAG 205

Query: 1864 IQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISK 1923
            +QG       QG       QG        G+       G   E     +      +G+  
Sbjct: 206  LQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKG 265

Query: 1924 EDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAA---QGIANEDA 1980
            +  V G      ++G        G+A    A+G   +    G+     A    G   E  
Sbjct: 266  DAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPG 325

Query: 1981 AQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIAN 2040
            + G      + G        G+        +      +G +      G+  E  + G+A 
Sbjct: 326  SAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPAGVKGEQGSPGLAG 385

Query: 2041 EDAAHGVANEDAAQAIAKPDAAHGIANE 2068
               A G A +   Q +       G+  E
Sbjct: 386  PKGAPGQAGQKGDQGVKGSSGEQGVKGE 413



 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 58/300 (19%), Positives = 89/300 (29%), Gaps = 9/300 (3%)

Query: 1705 VANEDAVQGVANEVEVQG---VAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAH 1761
            V++E  +Q V N  +  G   +  E    G+     A G+       G   E  A+G   
Sbjct: 125  VSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMG 184

Query: 1762 EDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADG 1821
             D   G +       V  E    G                +G        G+       G
Sbjct: 185  RDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETG 244

Query: 1822 IPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDA 1881
               E    G+       G+  +  V G      ++G        G+A     +G   +  
Sbjct: 245  TKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPG 304

Query: 1882 VQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAK 1941
            +QG+     A G        G A       +     + G +     +G       QG   
Sbjct: 305  LQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKG 364

Query: 1942 EDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHG 2001
            E  V G A      G+  E  + G+A    A G A +   QG+      QG+  E    G
Sbjct: 365  ESGVPGPA------GVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERG 418



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 61/316 (19%), Positives = 93/316 (29%), Gaps = 6/316 (1%)

Query: 167 IANEDAAQDIAKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDP 226
           I  E  A  +     A  +       G   E   +G    D A G +      GV  E  
Sbjct: 146 IKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAG 205

Query: 227 VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAN 286
           +QG       QG       QG        G+       G   E    G+      +G+  
Sbjct: 206 LQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKG 265

Query: 287 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQG 346
           +    G       +G        G+A    A G   +     +  P  A G        G
Sbjct: 266 DAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPG 325

Query: 347 IATEDVADGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGV--VANEDAAQAIAK 404
            A      G+     + G      + G       QG   E  + G   V  E  +  +A 
Sbjct: 326 SAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPAGVKGEQGSPGLAG 385

Query: 405 PDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQG 464
           P  A G A +    G+      QG+  E    G     +V+ + + +  +   +     G
Sbjct: 386 PKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERG-ENSVSVRIVGSSNRGRAEVYYSGTWG 444

Query: 465 IAHEDAVQGIANEDAV 480
              +D  Q   N DA+
Sbjct: 445 TICDDEWQ---NSDAI 457



 Score = 49.7 bits (117), Expect = 3e-05
 Identities = 55/280 (19%), Positives = 80/280 (28%), Gaps = 7/280 (2%)

Query: 573 IATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVT 632
           I  E  A G+     A G+       G   E   +G    D   G +      G+  E  
Sbjct: 146 IKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAG 205

Query: 633 AHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIA 692
             G       QG        G   ++     I  P    G   E    G+      +G+ 
Sbjct: 206 LQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIG-PKGETGTKGEKGDLGLPGSKGDRGMK 264

Query: 693 NEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAH 752
            +    G      + G        G+A    A+G   +  +QG+       G    V   
Sbjct: 265 GDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVP------GPPGAVGHP 318

Query: 753 GVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANED 812
           G   E    G      + G        G+       G+  +    G +      GV  E 
Sbjct: 319 GAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPAGVKGEQ 378

Query: 813 AAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHG 852
            + G+A    A G A +    GV      QGV  E    G
Sbjct: 379 GSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERG 418



 Score = 48.9 bits (115), Expect = 6e-05
 Identities = 61/289 (21%), Positives = 84/289 (29%), Gaps = 16/289 (5%)

Query: 546 VANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDA 605
           +  E  A  +     A G+       G   E  A G    D A G +      GV  E  
Sbjct: 146 IKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAG 205

Query: 606 VQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIA 665
           +QG        G       QG        G   +  + G   E    G    E     + 
Sbjct: 206 LQGPQGAPGKQGATGTPGPQG------EKGSKGDGGLIGPKGETGTKG----EKGDLGLP 255

Query: 666 KPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQ 725
                 G+  +    G      ++G        G+A    A G   +  +QG+     A 
Sbjct: 256 GSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAV 315

Query: 726 GIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHED 785
           G        G A      G+     + G       +G       QG   E  V G A   
Sbjct: 316 GHPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPA--- 372

Query: 786 AVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHG 834
              G+  E  + G+A    A G A +   QGV      QGV  E    G
Sbjct: 373 ---GVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERG 418



 Score = 48.5 bits (114), Expect = 8e-05
 Identities = 59/306 (19%), Positives = 85/306 (27%), Gaps = 16/306 (5%)

Query: 1633 IANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVA 1692
            I  E  A G+       G+       G   E  A+G    D   G +      GV  E  
Sbjct: 146  IKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAG 205

Query: 1693 AHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIAN 1752
              G       QG       QG        G+       G   E    G+       G+  
Sbjct: 206  LQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKG 265

Query: 1753 EDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQG 1812
            +    G       +G         +A    A G   +     +  P  A G        G
Sbjct: 266  DAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPG 325

Query: 1813 IATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVE 1872
             A      G+P    + G      + G +     QG   E    G A             
Sbjct: 326  SAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPA------------- 372

Query: 1873 VQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDA-VQGIA 1931
              GV  E    G+A    A G A +   QG+      Q +  E   +G +     + G +
Sbjct: 373  --GVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERGENSVSVRIVGSS 430

Query: 1932 NQDAAQ 1937
            N+  A+
Sbjct: 431  NRGRAE 436



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 53/262 (20%), Positives = 77/262 (29%), Gaps = 15/262 (5%)

Query: 920  GITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANED 979
            G   E+ A+    +D A   +      GV  E    G       QG       QG     
Sbjct: 172  GPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQG----- 226

Query: 980  AVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIA 1039
               G   +  + G   E   +G   +    G+       G+  +    G      ++G  
Sbjct: 227  -EKGSKGDGGLIGPKGETGTKG---EKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDF 282

Query: 1040 NEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVH 1099
                  G+A    A G   +  +QG+     A G        G A      G+       
Sbjct: 283  GRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSP 342

Query: 1100 GVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEV 1159
            G      + G       QG   E  V G A      GV  E    G+A    A G A + 
Sbjct: 343  GATGLKGSKGDTGLQGQQGRKGESGVPGPA------GVKGEQGSPGLAGPKGAPGQAGQK 396

Query: 1160 AAHGIANEDAAQGIANEDAAQG 1181
               G+      QG+  E   +G
Sbjct: 397  GDQGVKGSSGEQGVKGEKGERG 418



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 61/315 (19%), Positives = 91/315 (28%), Gaps = 11/315 (3%)

Query: 188 EDAAQGISKEDAVQG------IANEDAAQGIAKEDPVQG---VANEDPVQGVANEDAVQG 238
           E  AQG S+   +Q       +++E   Q +       G   +  E    G+       G
Sbjct: 104 EHLAQGASRLQVLQAQLTWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMG 163

Query: 239 VANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDA 298
           +       G   E   +G    D A G +      G+  E   QG       QG      
Sbjct: 164 MPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPG 223

Query: 299 VQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIAN 358
            QG        G+       G   E     +       G+  +    G      + G   
Sbjct: 224 PQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFG 283

Query: 359 EDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAH--GIANEVA 416
                G+A    A G   +  +QGV       G    +    +   P  A   G      
Sbjct: 284 RPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPG 343

Query: 417 AHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIAN 476
           A G+       G+  +    G S      G+  E  + G+A    A G A +   QG+  
Sbjct: 344 ATGLKGSKGDTGLQGQQGRKGESGVPGPAGVKGEQGSPGLAGPKGAPGQAGQKGDQGVKG 403

Query: 477 EDAVHGVAKEVAAHG 491
                GV  E    G
Sbjct: 404 SSGEQGVKGEKGERG 418



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 55/279 (19%), Positives = 79/279 (28%), Gaps = 6/279 (2%)

Query: 1606 IANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDA 1665
            I  E  A  +     A G+       G   E  A G    D   G +      G+  E  
Sbjct: 146  IKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAG 205

Query: 1666 AQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAH 1725
             QG       QG        G        G+       G   E    G+      +G+  
Sbjct: 206  LQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKG 265

Query: 1726 EDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHG 1785
            +  V G      + G        G+A    A+G   +  +QG+            V   G
Sbjct: 266  DAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGA------VGHPG 319

Query: 1786 VANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDA 1845
               E  +          G      A G+       G+  +    G +      G+  E  
Sbjct: 320  AKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPAGVKGEQG 379

Query: 1846 VQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQG 1884
              G+A    A G A +   QGV      QGV  E   +G
Sbjct: 380  SPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERG 418



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 48/262 (18%), Positives = 71/262 (27%), Gaps = 3/262 (1%)

Query: 65  AHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVAN 124
           A G+       G+       G   E  A G      A G +      GV  E   QG   
Sbjct: 152 APGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAGLQGPQG 211

Query: 125 EDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQD 184
               QG       QG        G+       G   E    G+      + +  +     
Sbjct: 212 APGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKGDAGVMG 271

Query: 185 IANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPV---QGVANEDAVQGVAN 241
                 ++G        G+A    A+G   +  +QGV          G   E    G   
Sbjct: 272 PPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPG 331

Query: 242 EVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQG 301
              + G        G+       G+  +    G +      G+  E  + G+A      G
Sbjct: 332 RAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPAGVKGEQGSPGLAGPKGAPG 391

Query: 302 IANEDAVHGVAKEVAAHGVANE 323
            A +    GV       GV  E
Sbjct: 392 QAGQKGDQGVKGSSGEQGVKGE 413



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 73/372 (19%), Positives = 115/372 (30%), Gaps = 30/372 (8%)

Query: 838  EDAAQGVAK------EVTAHGVTNEDAVQGVVNEEALHGV--VANEDAAQAIAKPDAAHG 889
            E  AQG ++      ++T   V++E  +Q V N     G+  +  E  A  +     A G
Sbjct: 104  EHLAQGASRLQVLQAQLTWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMG 163

Query: 890  IANE----GVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAA 945
            +       G   E  A+G         + +D A G +  +    +  +            
Sbjct: 164  MPGAPGPPGPPAEKGAKG--------AMGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGK 215

Query: 946  QGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHK 1005
            QG        G        G+       G   E    G+      +G+  +  V G    
Sbjct: 216  QGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGA 275

Query: 1006 DAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGI 1065
               +G        G+A    A G   +   QG+     A G        G +      G+
Sbjct: 276  QGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGL 335

Query: 1066 ANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAV 1125
                 + G      ++G       QG   E  V G A      GV  E    G+A     
Sbjct: 336  PGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPA------GVKGEQGSPGLAGPKGA 389

Query: 1126 QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHE 1185
             G A +   QGV      QG+  E    G  N V+   + + +  +         G   +
Sbjct: 390  PGQAGQKGDQGVKGSSGEQGVKGEKGERG-ENSVSVRIVGSSNRGRAEVYYSGTWGTICD 448

Query: 1186 DAVQGIANEDAV 1197
            D  Q   N DA+
Sbjct: 449  DEWQ---NSDAI 457



 Score = 45.1 bits (105), Expect = 8e-04
 Identities = 70/367 (19%), Positives = 109/367 (29%), Gaps = 40/367 (10%)

Query: 1272 IANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQG------VANEDPIQGVANEVEVQG 1325
            +A ED+      + A  G   E  AQG ++   +Q       V++E  +Q V N  +  G
Sbjct: 86   LAAEDSPSFSLLQSAHPG---EHLAQGASRLQVLQAQLTWVRVSHEHLLQRVDNFTQNPG 142

Query: 1326 VAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDA 1385
            +        I  E  A G+     A G+           E  A+G    D   G +    
Sbjct: 143  MFR------IKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQG 196

Query: 1386 AQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIAN 1445
              G+  E  +QG       QG       QG        G+       G   E    G+  
Sbjct: 197  PPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPG 256

Query: 1446 EDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARG 1505
                +G+  +    G       +G        G+A    A G   +     +  P  A G
Sbjct: 257  SKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVG 316

Query: 1506 IANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVT 1565
                    G A      G+     + G      ++G            +  +QG      
Sbjct: 317  HPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKG------------DTGLQG------ 358

Query: 1566 AHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIA 1625
              G   E  V G          V  E  +  +A P  A G A +     +      QG+ 
Sbjct: 359  QQGRKGESGVPGPAG-------VKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVK 411

Query: 1626 NQDAAQG 1632
             +   +G
Sbjct: 412  GEKGERG 418



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 65/342 (19%), Positives = 102/342 (29%), Gaps = 25/342 (7%)

Query: 1446 EDAAQGIANEDAAQG------IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAK 1499
            E  AQG +     Q       ++HE  +Q + N     G+ +      +  E  A  +  
Sbjct: 104  EHLAQGASRLQVLQAQLTWVRVSHEHLLQRVDNFTQNPGMFR------IKGEQGAPGLQG 157

Query: 1500 PDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQG 1559
               A G+       G   E  A G    D A G +      G+  E  + G       QG
Sbjct: 158  HKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQG 217

Query: 1560 VVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKD 1619
                    G        G++      +    E     +       G+  +          
Sbjct: 218  ATGTPGPQGEKGSKGDGGLIGPKG-ETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQ 276

Query: 1620 AAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIA 1679
             ++G   +    G+A    A G   +  +QG+     A G        G A      G+ 
Sbjct: 277  GSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLP 336

Query: 1680 NEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAH 1739
                  G      + G       QG   E  V G A      GV  E    G+A    A 
Sbjct: 337  GSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPA------GVKGEQGSPGLAGPKGAP 390

Query: 1740 GITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEV 1781
            G   +    G+      +G + E  V+G   E   +SV+  +
Sbjct: 391  GQAGQKGDQGV------KGSSGEQGVKGEKGERGENSVSVRI 426



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 48/245 (19%), Positives = 72/245 (29%), Gaps = 9/245 (3%)

Query: 57  IANEDADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANE 116
           +  + A    G      V+G A     QG   +  A G        G   +    G   E
Sbjct: 183 MGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGE 242

Query: 117 VAAQGVANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDI 176
              +G   E    G+      +G+  +  V G      + G        G+A    A+  
Sbjct: 243 TGTKG---EKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGD 299

Query: 177 AKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAV 236
             +   Q +     A G        G A      G+       G       +G       
Sbjct: 300 QGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQ 359

Query: 237 QGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHE 296
           QG   E  V G A      G+  E  + G+     A G A +   QG+      QG+  E
Sbjct: 360 QGRKGESGVPGPA------GVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGE 413

Query: 297 DAVQG 301
              +G
Sbjct: 414 KGERG 418



 Score = 42.4 bits (98), Expect = 0.006
 Identities = 53/287 (18%), Positives = 85/287 (29%), Gaps = 7/287 (2%)

Query: 1588 VANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDA 1647
            +  E  A  +     A G+           +  A+G   +D A G +      G+  E  
Sbjct: 146  IKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAG 205

Query: 1648 VQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVAN 1707
            +QG       QG       QG        G+       G   E    G+      +G+  
Sbjct: 206  LQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKG 265

Query: 1708 EDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQG 1767
            +  V G       +G        G+A    A G   +    G+     A G        G
Sbjct: 266  DAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPG 325

Query: 1768 IANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDA 1827
             A               G      A  +       G+  +   +G +      G+  E  
Sbjct: 326  SAGSPG------RAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPAGVKGEQG 379

Query: 1828 AHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQ 1874
            + G+A    A G + +   QG+      QG+  E   +G  N V V+
Sbjct: 380  SPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERG-ENSVSVR 425



 Score = 41.6 bits (96), Expect = 0.009
 Identities = 52/274 (18%), Positives = 78/274 (28%), Gaps = 4/274 (1%)

Query: 356 IANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEV 415
           I  E  A G+     A G+       G   E    G +   D A   + P    G+  E 
Sbjct: 146 IKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGR-DGATGPSGPQGPPGVKGEA 204

Query: 416 AAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIA 475
              G       QG        G        G+       G   E    G+      +G+ 
Sbjct: 205 GLQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMK 264

Query: 476 NEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVA---DGIANED 532
            +  V G      + G   +     +A    A+G   +   QG+     A    G   E 
Sbjct: 265 GDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEP 324

Query: 533 AVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVA 592
              G        G      A  +       G+  +   +G +      G+  E  + G+A
Sbjct: 325 GSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPAGVKGEQGSPGLA 384

Query: 593 NEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQG 626
                 G A +   QGV       GV  E   +G
Sbjct: 385 GPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERG 418



 Score = 39.7 bits (91), Expect = 0.036
 Identities = 61/306 (19%), Positives = 90/306 (29%), Gaps = 15/306 (4%)

Query: 510 IANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVA 569
           I  E  A G+     A G+       G   E  A G    D A   + P    G+  E  
Sbjct: 146 IKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAG 205

Query: 570 TQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAK 629
            QG        G        G        G+       G   E    G+      +G+  
Sbjct: 206 LQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKG 265

Query: 630 EVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQ 689
           +    G       +G        G+     A     +P    G+     A G        
Sbjct: 266 DAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQP-GLQGVPGPPGAVGHPGAKGEP 324

Query: 690 GIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEV 749
           G A      G+     + G +     +G       QG   E  V G A      GV  E 
Sbjct: 325 GSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPA------GVKGEQ 378

Query: 750 AAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVA 809
            + G+A      G A +   QGV      +G + E  V+G   E   + ++  +   G +
Sbjct: 379 GSPGLAGPKGAPGQAGQKGDQGV------KGSSGEQGVKGEKGERGENSVSVRIV--GSS 430

Query: 810 NEDAAQ 815
           N   A+
Sbjct: 431 NRGRAE 436



 Score = 35.0 bits (79), Expect = 0.88
 Identities = 30/168 (17%), Positives = 52/168 (30%), Gaps = 3/168 (1%)

Query: 56  DIANEDADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVAN 115
           D+    +    G+  +  V G      ++G        G+A    A G   +   QGV  
Sbjct: 251 DLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPG 310

Query: 116 E---VAAQGVANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDA 172
               V   G   E    G      + G        G+       G+  +   +G +    
Sbjct: 311 PPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPG 370

Query: 173 AQDIAKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQG 220
              +  E  +  +A    A G + +   QG+      QG+  E   +G
Sbjct: 371 PAGVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERG 418


>gi|11386161 alpha 2 type IX collagen [Homo sapiens]
          Length = 689

 Score = 57.4 bits (137), Expect = 2e-07
 Identities = 110/566 (19%), Positives = 161/566 (28%), Gaps = 31/566 (5%)

Query: 1001 GIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKED 1060
            G+   D I G        G        G A  D   G    D   G   E    GI    
Sbjct: 42   GVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVK 101

Query: 1061 AVQGIANEDAAQGIA-----NEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANED- 1114
               G+       G             G+  E  ++G   +    G +      G      
Sbjct: 102  GQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPG 161

Query: 1115 PVQGVANE-------DAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANE 1167
             +QG+          +   G+     +QGV      +GI  +    G        G + E
Sbjct: 162  TIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGE 221

Query: 1168 DAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGI 1227
               QGI      QGI     + G   E   HG    V A G            P    G 
Sbjct: 222  ---QGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGE 278

Query: 1228 ANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAV 1287
              +  + GI       GI     A G        G      ++G A +    G      +
Sbjct: 279  KGDEGSPGIRG---PQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGL 335

Query: 1288 QGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANE 1347
             G+  +   +G   +    G        G   +    G   E   QGI  +    G   E
Sbjct: 336  AGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQG---E 392

Query: 1348 DAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGV 1407
                G       Q    E    GI     + G+  +  + G  K  P +G   +  V G+
Sbjct: 393  RGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPG--KTGP-RGKVGDPGVAGL 449

Query: 1408 ANEVEVQGVAHE---DAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHE 1464
              E   +G + E      QG+  E    G + +  A G+       G       +G+  +
Sbjct: 450  PGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQ 509

Query: 1465 DAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGI 1524
               QG+   DA      +VA   +  + A  A++   A R     V   G        G 
Sbjct: 510  PGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVS---AKREALGAVGMMGPPGPPGPPGY 566

Query: 1525 ANEDAAHGVANEVAAQGIANEVAVHG 1550
              +   HG        GI   V   G
Sbjct: 567  PGKQGPHGHPGPRGVPGIVGAVGQIG 592



 Score = 55.1 bits (131), Expect = 8e-07
 Identities = 98/499 (19%), Positives = 144/499 (28%), Gaps = 40/499 (8%)

Query: 1785 GVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKED 1844
            GV   D       P    G        G A  D  DG P  D   G   E    GI    
Sbjct: 42   GVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVK 101

Query: 1845 AVQGIANEDAAQGIAKEDPIQ-----GVANEVEVQGVAHEDAVQGIANEDAAHGIANEDA 1899
               G+       G     P       G+  E+ ++G   +    G +      G      
Sbjct: 102  GQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPG 161

Query: 1900 A-QGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIA 1958
              QG+  E +A  +   +   G+     +QG+      +GI  +   QG        G  
Sbjct: 162  TIQGL--EGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQG------KPGPK 213

Query: 1959 NEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAAR 2018
             +V A G       QGI      QGI     + G   E   HG      A     P    
Sbjct: 214  GDVGASG------EQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEE 267

Query: 2019 GIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGI----ANEGIATED 2074
            G        G   ++ + GI       G         I   D   G      + G A + 
Sbjct: 268  GPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQP 327

Query: 2075 VADGI-------AEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANED 2127
             + G         +   +G   ++            G   ++   G   E+  QG+  + 
Sbjct: 328  GSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQK 387

Query: 2128 AAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIA 2187
               G    V   G       QG   E    G+     + GV  +   +G   K   +G  
Sbjct: 388  GDQGERGPV---GQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGD---KGSPGKTGPRGKV 441

Query: 2188 NEDAAQGVANEVAAHGVANE---DAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANED 2244
             +    G+  E    G + E      QGV  E    G + +  A GV       G     
Sbjct: 442  GDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLA 501

Query: 2245 AARHMAKEDAAQGIANEDA 2263
              R +  +   QG+   DA
Sbjct: 502  GNRGVPGQPGRQGVEGRDA 520



 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 95/513 (18%), Positives = 144/513 (28%), Gaps = 22/513 (4%)

Query: 1713 GVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANED 1772
            G+     +QGV      +GI  +    G        G + E   QGI      QGI    
Sbjct: 181  GMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGE---QGIPGPPGPQGIRGYP 237

Query: 1773 AVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVA 1832
             +     E   HG      A     P    G        G   ++ + GI       G  
Sbjct: 238  GMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPK 297

Query: 1833 NEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAH 1892
                  GI+ +D   G      + G A +    G       QG+A    V G        
Sbjct: 298  GATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPG------HQGLA---GVPGQPGTKGGP 348

Query: 1893 GIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANED 1952
            G   E   QG+           E   +G      + G       +G   +   QG     
Sbjct: 349  GDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPK 408

Query: 1953 AAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIA 2012
              QG        G+      +G   +   +G   +  V G+  E    G + E       
Sbjct: 409  GEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPG----- 463

Query: 2013 KPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIAT 2072
             P   +G+  E    G + +  A G+       G       + +       G+       
Sbjct: 464  -PKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATD 522

Query: 2073 EDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGV 2132
            + + D +A   +Q    E A  A  +   A G+       G       QG        GV
Sbjct: 523  QHIVD-VALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGV 581

Query: 2133 ANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHK--DAIQGIANED 2190
               V A G       +G   E    G        G+     + G+  +   AI G   + 
Sbjct: 582  PGIVGAVGQIGNTGPKGKRGEKGDPGEVGR-GHPGMPGPPGIPGLPGRPGQAINGKDGDR 640

Query: 2191 AAQGVANEVAAHGVANEDAAQGVANEVAAQGVA 2223
             + G   E    G+       G     A  G +
Sbjct: 641  GSPGAPGEAGRPGLPGPVGLPGFCEPAACLGAS 673



 Score = 51.6 bits (122), Expect = 9e-06
 Identities = 117/671 (17%), Positives = 191/671 (28%), Gaps = 59/671 (8%)

Query: 579  ADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVAN 638
            +DGI  ++   G A      G        G A  D   G    D   G   E    G+  
Sbjct: 46   SDGIDGDNGPPGKAGPPGPKGEP------GKAGPDGPDGKPGIDGLTGAKGEPGPMGIPG 99

Query: 639  EDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQ 698
                 G+     L G             P    G+  E+   G   +    G +      
Sbjct: 100  VKGQPGLPGPPGLPG-----PGFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPP 154

Query: 699  GIANEVAA-HGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANE 757
            G         G+  E +   +   +   G+     +QG+       G+  +    G    
Sbjct: 155  GKPGRPGTIQGL--EGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGP 212

Query: 758  DPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGV 817
                G + E   QG+      QGI     + G   E   HG    V A G       +G 
Sbjct: 213  KGDVGASGE---QGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGP 269

Query: 818  ANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNED------AVQGVVNEEALHGV 871
                   G   ++   G+       G        G+  +D       ++G   +    G 
Sbjct: 270  RGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGS 329

Query: 872  VANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIA 931
              ++  A    +P    G  ++G   E   QG+       G  K+   G   E   Q I 
Sbjct: 330  PGHQGLAGVPGQPGTKGGPGDQG---EPGPQGLPGFSGPPG--KEGEPGPRGEIGPQGIM 384

Query: 932  KQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQ 991
             Q            +G   E    G       QG   E    G+     + GV  +   +
Sbjct: 385  GQ------------KGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGD---K 429

Query: 992  GVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEV 1051
            G   +   +G      + G+  E    G + E    G       QG+  E    G + + 
Sbjct: 430  GSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKG------QQGVRGEPGYPGPSGDA 483

Query: 1052 AAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVA 1111
             A G+       G       +G+  +   QG+   DA      + A+  + +++A   V+
Sbjct: 484  GAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVS 543

Query: 1112 NEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQ 1171
             +    G      + G        G   +    G        GI   V   G       +
Sbjct: 544  AKREALGAV---GMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKR 600

Query: 1172 GIANEDAAQGIAH-----EDAVQGIANE--DAVHGVAKEVAAHGVANEDAAHAIAKPDAA 1224
            G   +    G  H        + G+      A++G   +  + G   E     +  P   
Sbjct: 601  GEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGL 660

Query: 1225 RGIANEVAAQG 1235
             G     A  G
Sbjct: 661  PGFCEPAACLG 671



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 80/423 (18%), Positives = 122/423 (28%), Gaps = 17/423 (4%)

Query: 1821 GIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGI-AKEDPIQGVANEVEVQGVAHE 1879
            G P      G+  E+   G   +    G +      G   +   IQG+    +   +   
Sbjct: 119  GPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADF--LCPT 176

Query: 1880 DAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGI 1939
            +   G+       G+      +GI  +   Q         G S E   QGI      QGI
Sbjct: 177  NCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGE---QGIPGPPGPQGI 233

Query: 1940 AKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAV 1999
                 + G   E    G    V A G       +G        G   ++   GI     +
Sbjct: 234  RGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGI 293

Query: 2000 HGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVA---DGIANEDAAHGVANEDAAQAI 2056
             G         I   D   G      + G A +  +    G+A      G       Q  
Sbjct: 294  TGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGE 353

Query: 2057 AKPDAAHGIANE-GIATEDVADG-IAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGV 2114
              P    G +   G   E    G I    + G   ++  +    Q    G       QG 
Sbjct: 354  PGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGP 413

Query: 2115 TNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEV 2174
                  QG+       G   +    G   +    G+  E   +G + E   +G       
Sbjct: 414  PGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQ------ 467

Query: 2175 QGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANE 2234
            QG+  +    G + +  A GV       G       +GV  +   QGV   DA      +
Sbjct: 468  QGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVD 527

Query: 2235 VAV 2237
            VA+
Sbjct: 528  VAL 530



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 84/445 (18%), Positives = 128/445 (28%), Gaps = 40/445 (8%)

Query: 419 GIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANED 478
           G+      QG+       GI  +   QG        G + E   QGI      QGI    
Sbjct: 181 GMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGE---QGIPGPPGPQGIRGYP 237

Query: 479 AVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVA 538
            + G   E   HG      A     P    G        G   ++ + GI     + G  
Sbjct: 238 GMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPK 297

Query: 539 NEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVH 598
                 G+  +D            G       +G A +    G        GV  +    
Sbjct: 298 GATGPPGINGKD------------GTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTK 345

Query: 599 GVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANE 658
           G   +    G        G   ++   G   E+   G+  +   QG             E
Sbjct: 346 GGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQG-------------E 392

Query: 659 DAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGI 718
                   P    G   E    GI       G+  +  + G   +    G   +  V G+
Sbjct: 393 RGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPG---KTGPRGKVGDPGVAGL 449

Query: 719 ANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEV 778
             E   +G + E   +G   +  V G        G A    VQG       +G+A     
Sbjct: 450 PGEKGEKGESGEPGPKG---QQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGN--- 503

Query: 779 QGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANE 838
           +G+  +   QG+   DA      +VA   +  + A   V+ +  A G      + G    
Sbjct: 504 RGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAV---GMMGPPGP 560

Query: 839 DAAQGVAKEVTAHGVTNEDAVQGVV 863
               G   +   HG      V G+V
Sbjct: 561 PGPPGYPGKQGPHGHPGPRGVPGIV 585



 Score = 49.3 bits (116), Expect = 5e-05
 Identities = 81/471 (17%), Positives = 130/471 (27%), Gaps = 31/471 (6%)

Query: 62  ADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQG 121
           A    GI      QG+       G   E   HG    V A G       +G        G
Sbjct: 218 ASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAG 277

Query: 122 VANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAA---QDIA- 177
              ++   G+     + G        GI  +D   G      + G A +  +   Q +A 
Sbjct: 278 EKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAG 337

Query: 178 -----KEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVAN 232
                          E   QG+       G   E   +G      + G   +   +G   
Sbjct: 338 VPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVG 397

Query: 233 EDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQG 292
           +   QG       QG       QG+       G   +    G   +    G+  E   +G
Sbjct: 398 QPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKG 457

Query: 293 IAHE---DAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIAT 349
            + E      QG+  E    G + +  A GV                G+  +   QG+  
Sbjct: 458 ESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEG 517

Query: 350 EDVADGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAH 409
            D  D    + A   + +++    V+ +    G V      G             P    
Sbjct: 518 RDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPG-------------PPGPP 564

Query: 410 GIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHED 469
           G   +   HG        GI   V   G +     +G   +    G  H     G+    
Sbjct: 565 GYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGH----PGMPGPP 620

Query: 470 AVQGIANE--DAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQG 518
            + G+      A++G   +  + G   +     +  P    G     A  G
Sbjct: 621 GIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLG 671



 Score = 48.9 bits (115), Expect = 6e-05
 Identities = 83/488 (17%), Positives = 138/488 (28%), Gaps = 35/488 (7%)

Query: 67  GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126
           G+   D + G        G        G A      G    D   G   E    G+    
Sbjct: 42  GVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVK 101

Query: 127 AVQGVANEDAVQG--------------VANEDAVQGIANEDAAHGIANEDAAQGIANEDA 172
              G+     + G              +  E  ++G   +    G +      G      
Sbjct: 102 GQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPG 161

Query: 173 AQDIAKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVAN 232
                 E +A  +   +   G+     +QG+      +GI  +   QG        G + 
Sbjct: 162 TIQ-GLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASG 220

Query: 233 EDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQG 292
           E   QG+      QG+     + G   E   HG    V A G       +G        G
Sbjct: 221 E---QGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAG 277

Query: 293 IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVAT---QGIA- 348
              ++   GI     + G        G+  +D          + G A +  +   QG+A 
Sbjct: 278 EKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAG 337

Query: 349 -----TEDVADGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIA 403
                      G   E    G+       G   E   +G +    + G   ++     + 
Sbjct: 338 VPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVG 397

Query: 404 K--PDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDA 461
           +  P    G   E    GI       G+  +  + G   +   +G   +    G+  E  
Sbjct: 398 QPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPG---KTGPRGKVGDPGVAGLPGEKG 454

Query: 462 AQGIAHE---DAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQG 518
            +G + E      QG+  E    G + +  A GV               RG+  +   QG
Sbjct: 455 EKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQG 514

Query: 519 IATEDVAD 526
           +   D  D
Sbjct: 515 VEGRDATD 522



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 94/532 (17%), Positives = 144/532 (27%), Gaps = 31/532 (5%)

Query: 1136 GVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 1195
            GV   D + G        G        G A  D   G    D   G   E    GI    
Sbjct: 42   GVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVK 101

Query: 1196 AVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVA 1255
               G+       G+     A     P    G+  E+  +G   +   DG +      G  
Sbjct: 102  GQPGLP---GPPGLPGPGFAGPPGPPGPV-GLPGEIGIRGPKGDPGPDGPSGPPGPPGKP 157

Query: 1256 N--------EVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQG 1307
                     E +A  +   +   G+      QG+      +GI  +   QG        G
Sbjct: 158  GRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVG 217

Query: 1308 VANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDA 1367
             + E   QG+      QG+     + G   E   HG      A G       +       
Sbjct: 218  ASGE---QGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPG 274

Query: 1368 AQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIAN 1427
              G   ++   GI       G        G+  +D   G        G A +    G   
Sbjct: 275  RAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQG 334

Query: 1428 EDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHG 1487
                 G        G   E   QG+       G   E   +G      + G   +    G
Sbjct: 335  LAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERG 394

Query: 1488 VANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVA 1547
               +        P   +G       QG+       G   +    G   +    G+  E  
Sbjct: 395  PVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKG 454

Query: 1548 VHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIA 1607
              G + E   +G        GV  E    G   +       A     Q    P    G+A
Sbjct: 455  EKGESGEPGPKG------QQGVRGEPGYPGPSGD-------AGAPGVQGYPGPPGPRGLA 501

Query: 1608 NEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQG 1659
                   +  +   QG+  +DA      +VA   + ++ A   ++ +  A G
Sbjct: 502  GN---RGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALG 550



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 61/333 (18%), Positives = 91/333 (27%), Gaps = 15/333 (4%)

Query: 56  DIANEDADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVAN 115
           D  ++      G       QG+      QG+       G   E   HG      A G   
Sbjct: 203 DPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATG 262

Query: 116 EVAAQGVANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQD 175
               +G        G   ++   G+     + G        GI  +D   G         
Sbjct: 263 PPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPG------ 316

Query: 176 IAKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDA 235
             K  A Q  A +  + G      V G        G   E   QG+       G   E  
Sbjct: 317 -MKGSAGQ--AGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPG 373

Query: 236 VQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAH 295
            +G      + G   +   +G   +    G        G       QG+      +G   
Sbjct: 374 PRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPG 433

Query: 296 EDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADG 355
           +   +G   +  V G+  E    G + E        P    G+  E    G + +  A G
Sbjct: 434 KTGPRGKVGDPGVAGLPGEKGEKGESGEPG------PKGQQGVRGEPGYPGPSGDAGAPG 487

Query: 356 IANEDAAHGVAKEVTAHGVANEDAVQGVVNEDA 388
           +       G        GV  +   QGV   DA
Sbjct: 488 VQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDA 520



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 67/382 (17%), Positives = 109/382 (28%), Gaps = 11/382 (2%)

Query: 1568 GVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQ 1627
            G+     +QGV        ++  +   Q    P    G + E     I      QGI   
Sbjct: 181  GMKGPPGLQGVKGHAGKRGILG-DPGHQGKPGPKGDVGASGE---QGIPGPPGPQGIRGY 236

Query: 1628 DAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1687
                G   E   HG        G       +G        G   ++   GI     + G 
Sbjct: 237  PGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGP 296

Query: 1688 AKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAA 1747
                   G+  +D   G        G A +    G      V G        G   E   
Sbjct: 297  KGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGP 356

Query: 1748 HGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANE 1807
             G+       G   E   +G      +     +    G   +        P   +G    
Sbjct: 357  QGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGI 416

Query: 1808 VAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGV 1867
               QG+       G P +    G   +    G+  E   +G + E   +G   +  ++G 
Sbjct: 417  PGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKG---QQGVRGE 473

Query: 1868 ANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAV 1927
                   G A    VQG        G+A     +G+  +   Q +   DA      + A+
Sbjct: 474  PGYPGPSGDAGAPGVQGYPGPPGPRGLAGN---RGVPGQPGRQGVEGRDATDQHIVDVAL 530

Query: 1928 QGIANQDAAQGI-AKEDAVQGI 1948
            + +  Q A   + AK +A+  +
Sbjct: 531  KMLQEQLAEVAVSAKREALGAV 552



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 54/310 (17%), Positives = 87/310 (28%), Gaps = 12/310 (3%)

Query: 946  QGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHK 1005
            +G        G+      QG+       G   E   HG        G       +G    
Sbjct: 213  KGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGP 272

Query: 1006 DAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAA------QGIANEVAAHGISKE 1059
                G   ++ + GI       G        GI  +D        +G A +    G    
Sbjct: 273  PGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGH 332

Query: 1060 DAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQ-- 1117
              + G+  +   +G   +    G        G   ++   G   E+   G+  +   Q  
Sbjct: 333  QGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGE 392

Query: 1118 -GVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANE 1176
             G   +   QG       QG       QG+       G   +    G   +    G+  E
Sbjct: 393  RGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGE 452

Query: 1177 DAAQGIAHE---DAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAA 1233
               +G + E      QG+  E    G + +  A GV               RG+  +   
Sbjct: 453  KGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGR 512

Query: 1234 QGIATEDVAD 1243
            QG+   D  D
Sbjct: 513  QGVEGRDATD 522


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score = 57.0 bits (136), Expect = 2e-07
 Identities = 121/679 (17%), Positives = 191/679 (28%), Gaps = 59/679 (8%)

Query: 893  EGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANED 952
            +G  +E +A  + T+  AD  A   A  I   + A  + + +       ED   G+  + 
Sbjct: 209  KGTGHEFSA-ALGTQGPADQRADARASCILAAKTAPGLKQLNGEPGERGED---GLPGKP 264

Query: 953  AAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIA 1012
               G   E    G   E    G+       GV  E   QG   E+ + G+      +G A
Sbjct: 265  GLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEA 324

Query: 1013 NEDAAHGIANEVAA----------HGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAV 1062
                  G+    +            G   E    G+  E   QG   E+   G +     
Sbjct: 325  GPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGA 384

Query: 1063 QGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANE 1122
            +G      A G A    A G        G        G+       G   E    G    
Sbjct: 385  KGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGS 444

Query: 1123 DAVQGVANEVEVQGVAH--------EDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIA 1174
                G   +    G+          E  ++G        G   +  A GI     ++G  
Sbjct: 445  PGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRG-- 502

Query: 1175 NEDAAQGIAHEDAVQGIANEDAV---HGVAKEVAAHGVANEDAAHAIAKPDAARGIANEV 1231
              D   G+A      G   +       G+       G A  D   ++  P     +A +V
Sbjct: 503  --DPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDV 560

Query: 1232 AAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIA 1291
                    D   G        G   +    G    +  +G   E    G+       GIA
Sbjct: 561  C------NDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLP---GPPGIA 611

Query: 1292 NEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQ 1351
                +QG                +G   EV  +G      V G        G    D   
Sbjct: 612  GPQGSQG---------------ERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIA 656

Query: 1352 GIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEV 1411
            G A     Q    ++   G      + GI  E+  +G    D   G   E    G     
Sbjct: 657  GAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEG---RDGKPGPPGEPGKAGEPGLP 713

Query: 1412 EVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIA 1471
              +G       +G   +  A G   E  A G+  +   +G+  +D   G       QG  
Sbjct: 714  GPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQ---EGLPGKDGDTGPTGPQGPQGPR 770

Query: 1472 NEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAH 1531
                 +G        G +           + + G+   +  +G   E    G+  ++   
Sbjct: 771  GPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVP 830

Query: 1532 GVANEVAAQGIANEVAVHG 1550
            G   E   +G   +  + G
Sbjct: 831  GKPGEPGFKGERGDPGIKG 849



 Score = 56.6 bits (135), Expect = 3e-07
 Identities = 118/648 (18%), Positives = 199/648 (30%), Gaps = 47/648 (7%)

Query: 769  VQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVAN 828
            + G   E    G+  +  ++G   E    G   E    G+       GV  E   QG   
Sbjct: 248  LNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKG 307

Query: 829  EDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAH 888
            E  + G+  +   +G A      G      + G  +    H  +  E   +         
Sbjct: 308  ELGLPGLKGDRGEKGEA------GPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLP 361

Query: 889  GIAN-EGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQG 947
            G    +G   E+  QG      A G  ++ AHG      A   A    A          G
Sbjct: 362  GEPGLQGRPGELGPQGPTGPPGAKG--QEGAHG------APGAAGNPGAPGHVGAPGPSG 413

Query: 948  VANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDA 1007
                  A G+       G   E  A G        G   +    G+      +G   +  
Sbjct: 414  PPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPG 472

Query: 1008 IQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIAN 1067
            ++G        G   +  A GI     ++G    D   G+A      G   +    G   
Sbjct: 473  LRGSPGLPGPLGTKGDRGAPGIPGSPGSRG----DPGIGVAGPPGPSGPPGDKGSPG--- 525

Query: 1068 EDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQG 1127
               ++G+      QG A  D +  + +   ++ +AK+V        D   G      + G
Sbjct: 526  ---SRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVC------NDCPPGPPGLPGLPG 576

Query: 1128 VANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDA 1187
               +  V G    +  +G   E    G+       GIA    +QG   E  A G   +  
Sbjct: 577  FKGDKGVPGKPGREGTEGKKGEAGPPGLP---GPPGIAGPQGSQG---ERGADGEVGQKG 630

Query: 1188 VQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIAN 1247
             QG      V G        G    D     A P   +G   +    G        GI  
Sbjct: 631  DQG---HPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPG 687

Query: 1248 EDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQG 1307
            E+   G   +    G   +    G+   + A+G       +G   +  A G   E    G
Sbjct: 688  EEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARG---PPGFKGHTGDSGAPGPRGESGAMG 744

Query: 1308 VANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDA 1367
            +  ++ + G   +    G       +G   ++ + G   E    G   +  ++    E+ 
Sbjct: 745  LPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSK---GENG 801

Query: 1368 AQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQG 1415
            + G+      +G   E   +G+  ++ V G   E   +G   +  ++G
Sbjct: 802  SPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKG 849



 Score = 55.8 bits (133), Expect = 5e-07
 Identities = 118/682 (17%), Positives = 197/682 (28%), Gaps = 42/682 (6%)

Query: 924  EEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHG 983
            ++ AQ    +     + +  A Q    +   H  +     QG A++ A    +   A   
Sbjct: 182  DQGAQGACGRGNTSVLPSSVAPQCSMPKGTGHEFSAALGTQGPADQRADARASCILAAKT 241

Query: 984  VANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDA 1043
                  + G   E    G+  K  ++G   E    G   E    G+       G+  E  
Sbjct: 242  APGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKG 301

Query: 1044 AQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAA----------QGIAHEDAVQGIA 1093
             QG   E+   G+  +   +G A      G+    +           QG   E    G+ 
Sbjct: 302  DQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLP 361

Query: 1094 NEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAH 1153
             E  + G   E+   G       +G        G A      G        G      A 
Sbjct: 362  GEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAP 421

Query: 1154 GIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANED 1213
            G+       G   E  A G        G   +    G+       G   E    G     
Sbjct: 422  GLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPGLRGSPGLP 480

Query: 1214 AAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIA 1273
                      A GI     ++G    D   G+A      G   +  + G       +G+ 
Sbjct: 481  GPLGTKGDRGAPGIPGSPGSRG----DPGIGVAGPPGPSGPPGDKGSPGS------RGLP 530

Query: 1274 NEDAAQGIAKEDAVQGIANEDAAQGIAKE---DPVQGVANEDPIQGVANEVEVQGVAHED 1330
                 QG A  D +  + +      +AK+   D   G      + G   +  V G    +
Sbjct: 531  GFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGRE 590

Query: 1331 AVQGIANE------DAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANED 1384
              +G   E          GIA    +QG    D       +    G+       G     
Sbjct: 591  GTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPP 650

Query: 1385 AAQGI---AKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAH 1441
             A GI   A    +QG   ++   G      + G+  E+  +G   +    G   +    
Sbjct: 651  GADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEP 710

Query: 1442 GIANEDAA------QGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAH 1495
            G+   + A      +G   +  A G   E    G+  ++ + G   +    G        
Sbjct: 711  GLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPR 770

Query: 1496 AIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIED 1555
                 + + G   E    G   +    G   E+ + G+   +  +G   E    GV  ++
Sbjct: 771  GPPGKNGSPGSPGEPGPSGTPGQ---KGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKE 827

Query: 1556 AVQGVVKEVTAHGVANEDAVQG 1577
             V G   E    G   +  ++G
Sbjct: 828  GVPGKPGEPGFKGERGDPGIKG 849



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 153/866 (17%), Positives = 238/866 (27%), Gaps = 70/866 (8%)

Query: 1391 KEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDA-- 1448
            + DP + V  +   QG         +    A Q    +   H  +  +   G A++ A  
Sbjct: 174  RTDPWENV--DQGAQGACGRGNTSVLPSSVAPQCSMPKGTGHEFSAALGTQGPADQRADA 231

Query: 1449 -AQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIA 1507
             A  I     A G+   +   G   ED + G        G+  E     +A     +G A
Sbjct: 232  RASCILAAKTAPGLKQLNGEPGERGEDGLPGKP------GLRGEIGEQGLAGRPGEKGEA 285

Query: 1508 NEVATQGIATEDVADGIANEDAAHGVANEVAAQGIAN---EVAVHGVAIEDAVQGVVKEV 1564
                  G        G+  E    G   E+   G+     E    G A    + G     
Sbjct: 286  GLPGAPGFP------GVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLF 339

Query: 1565 TAH-------GVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIAN 1617
            T H       G   E    G+  E  L      E   Q    P  A G      A   A 
Sbjct: 340  TPHPRMPGEQGPKGEKGDPGLPGEPGLQGR-PGELGPQGPTGPPGAKGQEGAHGAPGAAG 398

Query: 1618 KDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQG 1677
               A G        G    V A G+       G   E  A G        G   +    G
Sbjct: 399  NPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPG 458

Query: 1678 IANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDA 1737
            +       G   E    G        G   +    G+      +G    D   G+A    
Sbjct: 459  LPGPPG-KGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRG----DPGIGVAGPPG 513

Query: 1738 AHGITNEVAA---HGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHA 1794
              G   +  +    G+      QG A  D +  + +   ++ +AK+V             
Sbjct: 514  PSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCN----------- 562

Query: 1795 IAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDA 1854
                D   G        G   +    G P  +   G   E    G+       GIA    
Sbjct: 563  ----DCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLP---GPPGIAGPQG 615

Query: 1855 AQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAN 1914
            +QG       +G   EV  +G      V G        G    D   G A     Q    
Sbjct: 616  SQG------ERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPG 669

Query: 1915 EDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQG 1974
            ++   G      + GI  ++  +G    D   G   E    G        G       +G
Sbjct: 670  KEGPPGPQGPSGLPGIPGEEGKEG---RDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKG 726

Query: 1975 IANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDV 2034
               +  A G   E    G+  ++ + G   +        P   RG   +  + G   E  
Sbjct: 727  HTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPG 786

Query: 2035 ADGIANEDAAHGVANEDAAQAIAKPDAAHGIANE-GIATEDVADGIAEDAVQGITNEEAA 2093
              G   +  + G            P    G   E G+  ++   G  +    G   E   
Sbjct: 787  PSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPG--KPGEPGFKGERGD 844

Query: 2094 QAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANE 2153
              I       G   +    G+       G+       G    V   G   +    G+  E
Sbjct: 845  PGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGE 904

Query: 2154 VAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGV 2213
              +         + +  ++E + +A+  A    A   ++QG        G   +D   G 
Sbjct: 905  SPSMETLRRLIQEELGKQLETR-LAYLLAQMPPAYMKSSQG---RPGPPGPPGKDGLPGR 960

Query: 2214 ANEVAAQGVANEDAAQGVANEVAVHG 2239
            A  +   G   +   +G +  +   G
Sbjct: 961  AGPMGEPGRPGQGGLEGPSGPIGPKG 986



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 124/691 (17%), Positives = 202/691 (29%), Gaps = 49/691 (7%)

Query: 125 EDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQD 184
           +   QG         + +  A Q    +   H  +     QG A++ A    +   AA+ 
Sbjct: 182 DQGAQGACGRGNTSVLPSSVAPQCSMPKGTGHEFSAALGTQGPADQRADARASCILAAKT 241

Query: 185 IANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVE 244
                   G   E    G+  +   +G   E  + G   E    G+       GV  E  
Sbjct: 242 APGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKG 301

Query: 245 VQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAA-QGIANEDAAQGIAHEDAVQGIA 303
            QG   E  + G+  +    G        G+    +           QG   E    G+ 
Sbjct: 302 DQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLP 361

Query: 304 NEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAH 363
            E  + G   E+   G      A      + AHG        G      A G +    + 
Sbjct: 362 GEPGLQGRPGELGPQGPTGPPGAKG---QEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSV 418

Query: 364 GVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKP-DAAHGIANEVAAHGIAN 422
           G        G   E   +G   E+   G V       A   P     G   E    G   
Sbjct: 419 GAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPG 478

Query: 423 EDAAQGIANEVAAHGI-----SKEDAVQGIA------------NEDAAQGIAHEDAAQGI 465
                G   +  A GI     S+ D   G+A                ++G+      QG 
Sbjct: 479 LPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGP 538

Query: 466 AHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVA 525
           A  D +  + +   ++ +AK+V             +      +G+  +   +G   +   
Sbjct: 539 AGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGE 598

Query: 526 DGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAH-GIANEVATQGIATEDVADGIAN 584
            G        G+A    + G    D      K D  H G+   +   G      ADGIA 
Sbjct: 599 AGPPGLPGPPGIAGPQGSQGERGAD-GEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIA- 656

Query: 585 EDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQG 644
                G A    + G   ++   G      + G+  E+  +G        G        G
Sbjct: 657 -----GAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEG------RDGKPGPPGEPG 705

Query: 645 VVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEV 704
              E  L G        +    P    G   +  A G   E  A G+  ++   G   + 
Sbjct: 706 KAGEPGLPG-------PEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDT 758

Query: 705 AAHGISKEDAVQGIANEDAAQGIAHE------DAVQGIANEDAVHGVAKEVAAHGVANED 758
              G       +G   ++ + G   E         +G   E+   G+   +   G   E 
Sbjct: 759 GPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEP 818

Query: 759 PVQGVANEDVVQGVANEVEVQGIAHEDAVQG 789
             +GV  ++ V G   E   +G   +  ++G
Sbjct: 819 GEKGVPGKEGVPGKPGEPGFKGERGDPGIKG 849



 Score = 48.1 bits (113), Expect = 1e-04
 Identities = 124/678 (18%), Positives = 186/678 (27%), Gaps = 65/678 (9%)

Query: 337 GIANEVATQGIATEDVADGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVAN- 395
           G+  E+  QG+A      G A    A G        GV  E   QG   E  L G+  + 
Sbjct: 265 GLRGEIGEQGLAGRPGEKGEAGLPGAPGFP------GVRGEKGDQGEKGELGLPGLKGDR 318

Query: 396 -EDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQ 454
            E      A P    G  +    H        QG   E    G+  E  +QG   E   Q
Sbjct: 319 GEKGEAGPAGPPGLPGTTSLFTPH--PRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQ 376

Query: 455 GIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEV 514
           G      A+G            ++  HG      A G A    A          G    V
Sbjct: 377 GPTGPPGAKG------------QEGAHG------APGAAGNPGAPGHVGAPGPSGPPGSV 418

Query: 515 AAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDA-----------AHG 563
            A G+      DG   E    G        G   +  A  +  P             + G
Sbjct: 419 GAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPG 478

Query: 564 IANEVATQGI-----------ATEDVADGIANEDAAHGVANEVAV---HGVAIEDAVQGV 609
           +   + T+G            +  D   G+A      G   +       G+      QG 
Sbjct: 479 LPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGP 538

Query: 610 ANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDA 669
           A  D +  + +      +AK+V          + G+       GV           K   
Sbjct: 539 AGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGE 598

Query: 670 AHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAH 729
           A G        GIA    +QG       +G   EV   G      V G        G   
Sbjct: 599 A-GPPGLPGPPGIAGPQGSQG------ERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPG 651

Query: 730 EDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQG 789
            D + G A    + G   +    G      + G+  E+  +G   +    G   +    G
Sbjct: 652 ADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPG 711

Query: 790 IANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVT 849
           +   + A G        G   +  A G   E  A G+  ++ + G   +    G      
Sbjct: 712 LPGPEGARG---PPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQG 768

Query: 850 AHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDV 909
             G   ++   G   E    G    + +      P     +   G   E   +G+  ++ 
Sbjct: 769 PRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEG 828

Query: 910 ADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANE 969
             G  K    G   E     I           +    G+       G+       G    
Sbjct: 829 VPG--KPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGP 886

Query: 970 VAAQGVANEDAVHGVANE 987
           V   G   +    G+  E
Sbjct: 887 VGPPGPPGQPGFPGLRGE 904



 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 102/568 (17%), Positives = 153/568 (26%), Gaps = 45/568 (7%)

Query: 1721 QGVAHEDAV----QGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHS 1776
            +G  HE +     QG A++ A    +  +AA          G   E    G+  +  +  
Sbjct: 209  KGTGHEFSAALGTQGPADQRADARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRG 268

Query: 1777 VAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVA 1836
               E    G   E     +       G+  E   QG   E    G+  +    G A    
Sbjct: 269  EIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAG 328

Query: 1837 AHGISKEDAV----------QGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIA 1886
              G+    ++          QG   E    G+  E  +QG   E+  QG       +G  
Sbjct: 329  PPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQE 388

Query: 1887 NEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQ 1946
                A G A    A G               A G+       G   +  A G        
Sbjct: 389  GAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPV 448

Query: 1947 GIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANED 2006
            G   +  A G+       G   E   +G        G   +    GI       G    D
Sbjct: 449  GPRGDPGAPGLPGP-PGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRG----D 503

Query: 2007 AAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPD----AA 2062
                +A P    G   +  + G      + G+       G A  D   ++  P      A
Sbjct: 504  PGIGVAGPPGPSGPPGDKGSPG------SRGLPGFPGPQGPAGRDGLSSLLSPGDINLLA 557

Query: 2063 HGIANEGIATEDVADGI----AEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEV 2118
              + N+         G+     +  V G    E  +    +    G+       G+    
Sbjct: 558  KDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLP---GPPGIAGPQ 614

Query: 2119 AAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIA 2178
             +QG        G   EV   G        G        G    D + G A    +QG  
Sbjct: 615  GSQG------ERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSP 668

Query: 2179 HKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVH 2238
             K+   G        G+  E    G    D   G   E    G       +G        
Sbjct: 669  GKEGPPGPQGPSGLPGIPGE---EGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFK 725

Query: 2239 GVANEDAARHMAKEDAAQGIANEDAAHG 2266
            G   +  A     E  A G+  ++   G
Sbjct: 726  GHTGDSGAPGPRGESGAMGLPGQEGLPG 753



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 91/531 (17%), Positives = 144/531 (27%), Gaps = 33/531 (6%)

Query: 1719 EVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVA 1778
            ++ G   E    G+  +    G   E    G   E    G+       G+  E       
Sbjct: 247  QLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEK 306

Query: 1779 KEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAH 1838
             E+   G+  +      A P    G+          T  +    P      G   E    
Sbjct: 307  GELGLPGLKGDRGEKGEAGPAGPPGLPG--------TTSLFTPHPRMPGEQGPKGEKGDP 358

Query: 1839 GISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANED 1898
            G+  E  +QG   E   QG       +G        G A      G        G     
Sbjct: 359  GLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSV 418

Query: 1899 AAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIA 1958
             A G+           E  A G        G      A G+      +G   E   +G  
Sbjct: 419  GAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPGLRGSP 477

Query: 1959 NEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAAR 2018
                  G   +  A GI     ++G    D   G+A      G   +  +        +R
Sbjct: 478  GLPGPLGTKGDRGAPGIPGSPGSRG----DPGIGVAGPPGPSGPPGDKGS------PGSR 527

Query: 2019 GIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGI----ANEGIATED 2074
            G+      QG A  D    + +    + +A +        P    G+     ++G+  + 
Sbjct: 528  GLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKP 587

Query: 2075 VADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAH-GVA 2133
              +G      +G   E     +       G       +G   EV  +G    D  H GV 
Sbjct: 588  GREG-----TEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKG----DQGHPGVP 638

Query: 2134 NEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQ 2193
              +   G      A G+A      G+      +G        G+      +G    D   
Sbjct: 639  GFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKP 698

Query: 2194 GVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANED 2244
            G   E    G       +G       +G   +  A G   E    G+  ++
Sbjct: 699  GPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQE 749



 Score = 38.9 bits (89), Expect = 0.061
 Identities = 45/262 (17%), Positives = 79/262 (30%), Gaps = 12/262 (4%)

Query: 76  GVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANED 135
           G+A    +QG        G   EV   G        G        G    D + G A   
Sbjct: 609 GIAGPQGSQG------ERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPP 662

Query: 136 AVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQGIS 195
            +QG   ++   G        GI  E+  +G   +        +     +   + A+G  
Sbjct: 663 GIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARG-- 720

Query: 196 KEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQ 255
                +G   +  A G   E    G+  ++ + G   +    G       +G   ++   
Sbjct: 721 -PPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSP 779

Query: 256 GIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEV 315
           G   E    G   +  + G   E+ + G+      +G   E   +G+  ++ V G   E 
Sbjct: 780 GSPGEPGPSGTPGQKGSKG---ENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEP 836

Query: 316 AAHGVANEDAAHAIAKPDAAHG 337
              G   +        P    G
Sbjct: 837 GFKGERGDPGIKGDKGPPGGKG 858



 Score = 33.9 bits (76), Expect = 2.0
 Identities = 51/308 (16%), Positives = 81/308 (26%), Gaps = 6/308 (1%)

Query: 84  QGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEDAVQGVANE 143
           +GV  +    G   +    G        G+A    +QG    D   G   +    GV   
Sbjct: 581 KGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGF 640

Query: 144 DAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQGISKEDAVQGI 203
               G      A GIA      GI      +          +      +G    D   G 
Sbjct: 641 MGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGP 700

Query: 204 ANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAA 263
             E    G       +G       +G   +    G   E    G+  +   +G+  +D  
Sbjct: 701 PGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQ---EGLPGKDGD 757

Query: 264 HGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANE 323
            G T      G        G        G +     +G   E+   G+   +   G   E
Sbjct: 758 TGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGE 817

Query: 324 DAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKEVTAHGVANEDAVQGV 383
                +       G+  +    G   E    GI  +    G   +    G+       G+
Sbjct: 818 PGEKGV---PGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGL 874

Query: 384 VNEDALHG 391
           +    L G
Sbjct: 875 MGPQGLPG 882



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 45/261 (17%), Positives = 78/261 (29%), Gaps = 18/261 (6%)

Query: 75  QGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQ---GVANEVAAQGVANEDAVQGV 131
           +GV  +   +G   +    G        G+A    +Q   G   EV  +G      V G 
Sbjct: 581 KGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGF 640

Query: 132 ---------ANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAA 182
                       D + G A    +QG   ++   G        GI  E+  +     D  
Sbjct: 641 MGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEG---RDGK 697

Query: 183 QDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANE 242
                E    G       +G       +G   +    G   E    G+  ++ + G   +
Sbjct: 698 PGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGD 757

Query: 243 VEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGI 302
               G       +G   ++ + G   E    G   +  ++G   E+ + G+      +G 
Sbjct: 758 TGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKG---ENGSPGLPGFLGPRGP 814

Query: 303 ANEDAVHGVAKEVAAHGVANE 323
             E    GV  +    G   E
Sbjct: 815 PGEPGEKGVPGKEGVPGKPGE 835


>gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens]
          Length = 957

 Score = 56.6 bits (135), Expect = 3e-07
 Identities = 66/331 (19%), Positives = 106/331 (32%), Gaps = 21/331 (6%)

Query: 1028 GIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHED 1087
            G+       G   +D   G        G+     +QG      A+G+       G   + 
Sbjct: 461  GLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQG------ARGLPGYKGEPGRDGDK 514

Query: 1088 AVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIA 1147
              +G+     +HG+       G   +    G   +   +G       +G A    + G A
Sbjct: 515  GDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKG------EKGNAGFPGLPGPA 568

Query: 1148 NEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAH 1207
             E   HG    + + G   E  + G   +D  +G   E  + G      + G   E+   
Sbjct: 569  GEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRG---EPGIPGFPGNRGLMGQKGEIGPP 625

Query: 1208 GVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKED 1267
            G   +  A  +     + G   +    G        GI     A G+  E  A G   E 
Sbjct: 626  GQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEP 685

Query: 1268 ---AVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQ 1324
                + GI  +   +G   E  +QG   E+  QGI  +  +QG       +G   E  V+
Sbjct: 686  GYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVR 745

Query: 1325 GV---AHEDAVQGIANEDAAHGIANEDAAQG 1352
            G      E  V G+       G   +   QG
Sbjct: 746  GAIGSKGESGVDGLMGPAGPKGQPGDPGPQG 776



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 65/345 (18%), Positives = 100/345 (28%), Gaps = 42/345 (12%)

Query: 1005 KDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQG 1064
            K   QGIA      G      A G+       G   +   +G+      HG+       G
Sbjct: 477  KPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMG 536

Query: 1065 IANEDAAQGIANEDAAQGIAHEDAVQGI---ANEDAVHGVAKEVAAHGVANEDPVQGVAN 1121
               +  + G   +  A+G        G+   A E   HG    + + G   E    G   
Sbjct: 537  AKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPG 596

Query: 1122 EDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQG 1181
            +D  +G            E  + G        G   E+   G   +  A G+     + G
Sbjct: 597  QDGTRG------------EPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNG 644

Query: 1182 IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDV 1241
               +    G        G+     A G+  E           A G   E    G+     
Sbjct: 645  SPGQPGTPGSKGSKGEPGIQGMPGASGLKGE---------PGATGSPGEPGYMGLP---- 691

Query: 1242 ADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAK 1301
                       G+  +    G   E  +QG   E+  QGI  +  +QG       +G   
Sbjct: 692  -----------GIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKG 740

Query: 1302 EDPVQGV---ANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHG 1343
            E  V+G      E  + G+      +G   +   QG    D   G
Sbjct: 741  EPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPG 785



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 75/384 (19%), Positives = 117/384 (30%), Gaps = 30/384 (7%)

Query: 942  EDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQG 1001
            E  A+G       +G       +G A      G A E   HG        G   E    G
Sbjct: 534  EMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPG 593

Query: 1002 IAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDA 1061
               +D  +G   E    G        G   E    G   +  A G+   + ++G   +  
Sbjct: 594  APGQDGTRG---EPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPG 650

Query: 1062 VQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDA---VHGVAKEVAAHGVANEDPVQG 1118
              G        GI     A G+  E    G   E     + G+  +    G   E  +QG
Sbjct: 651  TPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQG 710

Query: 1119 VANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDA 1178
               E+  QG+  +   QG+      +G   E    G+   + + G +  D   G A    
Sbjct: 711  QKGENGRQGIPGQ---QGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKG 767

Query: 1179 AQGIAHEDAVQGI-------ANEDAVHGVAKEV---------AAHGVANEDAAHAIAKPD 1222
              G        G+        +E  +  V  +V          +  + N D  H +++  
Sbjct: 768  QPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCD--HCLSQ-H 824

Query: 1223 AARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIA 1282
             + GI       G        G+   D   G+       G+     + G   E  +QG  
Sbjct: 825  GSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFG 884

Query: 1283 --KEDAVQGIANEDAAQGIAKEDP 1304
               E    G    +   GI+KE P
Sbjct: 885  YPGEQGPPGPPGPEGPPGISKEGP 908



 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 68/337 (20%), Positives = 100/337 (29%), Gaps = 24/337 (7%)

Query: 1623 GIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 1682
            G   QD   G        G+     +QG       +G    D  +G   +  + G     
Sbjct: 470  GQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKG---DRGLPGFPGLH 526

Query: 1683 AVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIT 1742
             + G   E+ A G        G       +G A    + G A E    G      + G  
Sbjct: 527  GMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFK 586

Query: 1743 NEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAAR 1802
             E  + G   +D  +G   E  + G      +     E+   G   +  A  +     + 
Sbjct: 587  GEAGSPGAPGQDGTRG---EPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSN 643

Query: 1803 GIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDA---VQGIANEDAAQGIA 1859
            G   +    G        GI     A G+  E  A G   E     + GI  +   +G  
Sbjct: 644  GSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQ 703

Query: 1860 KEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQ 1919
             E  IQG   E   QG+  +  +QG      A G   E    G+              A 
Sbjct: 704  GEKGIQGQKGENGRQGIPGQQGIQG---HHGAKGERGEKGEPGVR------------GAI 748

Query: 1920 GISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQG 1956
            G   E  V G+      +G   +   QG    D   G
Sbjct: 749  GSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPG 785



 Score = 45.4 bits (106), Expect = 7e-04
 Identities = 60/312 (19%), Positives = 91/312 (29%), Gaps = 25/312 (8%)

Query: 517 QGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATE 576
           QGIA      G        G+       G   +     +      HG+       G   +
Sbjct: 481 QGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGD 540

Query: 577 DVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGV 636
             + G   +  A G        G+       G A E   HG      + G   E  + G 
Sbjct: 541 KGSPGFYGKKGAKGEKGNAGFPGLP------GPAGEPGRHGKDGLMGSPGFKGEAGSPGA 594

Query: 637 ANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDA 696
             +D  +G   E  + G   N              G   E+   G   +  A G+     
Sbjct: 595 PGQDGTRG---EPGIPGFPGNRGLM----------GQKGEIGPPGQQGKKGAPGMPGLMG 641

Query: 697 AQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDA---VHGVAKEVAAHG 753
           + G   +    G        GI     A G+  E    G   E     + G+  +    G
Sbjct: 642 SNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKG 701

Query: 754 VANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDA 813
              E  +QG   E+  QG+  +   QGI      +G   E    G+   + + G +  D 
Sbjct: 702 NQGEKGIQGQKGENGRQGIPGQ---QGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDG 758

Query: 814 AQGVANEDAAQG 825
             G A      G
Sbjct: 759 LMGPAGPKGQPG 770



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 57/307 (18%), Positives = 83/307 (27%), Gaps = 9/307 (2%)

Query: 974  GVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANED 1033
            G   +    G+A    V G       +G+       G   +    G+      HG+    
Sbjct: 473  GQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSK 532

Query: 1034 AAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIA 1093
               G   +  + G   +  A G       +G A      G A E    G   +D + G  
Sbjct: 533  GEMGAKGDKGSPGFYGKKGAKG------EKGNAGFPGLPGPAGEPGRHG---KDGLMGSP 583

Query: 1094 NEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAH 1153
                  G        G   E  + G      + G   E+   G   +    G+     ++
Sbjct: 584  GFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSN 643

Query: 1154 GIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANED 1213
            G   +    G        GI     A G+  E    G   E    G+       G     
Sbjct: 644  GSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQ 703

Query: 1214 AAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIA 1273
                I       G       QGI     A G   E    GV   + + G S  D + G A
Sbjct: 704  GEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPA 763

Query: 1274 NEDAAQG 1280
                  G
Sbjct: 764  GPKGQPG 770



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 55/302 (18%), Positives = 84/302 (27%), Gaps = 18/302 (5%)

Query: 946  QGVANEDAAHGVANEDAAQGVA---------NEVAAQGVANEDAVHGVANEDAVQGVANE 996
            QG+A      G      A+G+           +   +G+     +HG+       G   +
Sbjct: 481  QGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGD 540

Query: 997  VEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGI 1056
                G   K   +G        G+       G   +D   G        G        G 
Sbjct: 541  KGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGT 600

Query: 1057 SKEDAVQGIANEDAAQGIANE---DAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANE 1113
              E  + G        G   E      QG      + G+   +   G      + G   E
Sbjct: 601  RGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGE 660

Query: 1114 DPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGI 1173
              +QG+     ++G        G      + GI  +    G   E    G   E+  QGI
Sbjct: 661  PGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGI 720

Query: 1174 ANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAA 1233
              +   QG       +G   E  V G      A G   E     +  P   +G   +   
Sbjct: 721  PGQQGIQGHHGAKGERGEKGEPGVRG------AIGSKGESGVDGLMGPAGPKGQPGDPGP 774

Query: 1234 QG 1235
            QG
Sbjct: 775  QG 776



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 55/321 (17%), Positives = 91/321 (28%), Gaps = 6/321 (1%)

Query: 1702 VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAH 1761
            +QG   +  + G        G   +   QGIA      G      A G+       G   
Sbjct: 453  LQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDG 512

Query: 1762 EDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADG 1821
            +   +G+     +H +       G   +  +        A+G        G+       G
Sbjct: 513  DKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPG 572

Query: 1822 IPNEDA---AHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAH 1878
               +D    + G   E  + G   +D  +G   E    G      + G   E+   G   
Sbjct: 573  RHGKDGLMGSPGFKGEAGSPGAPGQDGTRG---EPGIPGFPGNRGLMGQKGEIGPPGQQG 629

Query: 1879 EDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQG 1938
            +    G+     ++G   +    G         I     A G+  E    G   +    G
Sbjct: 630  KKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMG 689

Query: 1939 IAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDA 1998
            +      +G       +GI  +   +G       QGI     A+G   E    G+     
Sbjct: 690  LPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIG 749

Query: 1999 VHGVANEDAAHAIAKPDAARG 2019
              G +  D     A P    G
Sbjct: 750  SKGESGVDGLMGPAGPKGQPG 770



 Score = 42.4 bits (98), Expect = 0.006
 Identities = 90/517 (17%), Positives = 150/517 (29%), Gaps = 42/517 (8%)

Query: 1305 VQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAN 1364
            +QG   +  + G        G   +   QGIA      G      A+G+           
Sbjct: 453  LQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDG 512

Query: 1365 EDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQG 1424
            +   +G+     + G+       G   +    G   +   +G       +G A    + G
Sbjct: 513  DKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKG------EKGNAGFPGLPG 566

Query: 1425 IANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVA 1484
             A E   HG    + + G   E  + G   +D  +G   E  + G      + G   E+ 
Sbjct: 567  PAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRG---EPGIPGFPGNRGLMGQKGEIG 623

Query: 1485 AHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIAN 1544
              G   +  A  +     + G   +  T G        GI     A G+  E  A G   
Sbjct: 624  PPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPG 683

Query: 1545 EVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAH 1604
            E    G      + G+  +    G   E  +QG   E+    +   +            H
Sbjct: 684  EPGYMG------LPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGI-------QGHH 730

Query: 1605 GIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANED 1664
            G   E           A G   +    G+       G   +   QG    D   G    +
Sbjct: 731  GAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSE 790

Query: 1665 AAQGIAHEDAVQG----IANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEV 1720
                    D ++     +     +      ++ HG        G    +  +G      +
Sbjct: 791  QFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRG------L 844

Query: 1721 QGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAH--EDAVQGIANEDAVHSVA 1778
             G+   D V G+       G+       G   E  +QG  +  E    G    +    ++
Sbjct: 845  PGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGIS 904

Query: 1779 KE--VAAHGVANEDAAHAIAKPDAARGIANEVAAQGI 1813
            KE      G+  +D  H   KP    GI  +    GI
Sbjct: 905  KEGPPGDPGLPGKDGDH--GKP----GIQGQPGPPGI 935



 Score = 42.4 bits (98), Expect = 0.006
 Identities = 79/474 (16%), Positives = 131/474 (27%), Gaps = 17/474 (3%)

Query: 1279 QGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANE 1338
            QGIA    V G      A+G+       G   +   +G+     + G+       G   +
Sbjct: 481  QGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGD 540

Query: 1339 DAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGV 1398
              + G   +  A+G         +       G   +D + G        G        G 
Sbjct: 541  KGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGT 600

Query: 1399 ANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAA 1458
              E  + G      + G   E    G   +  A G+   + ++G   +    G       
Sbjct: 601  RGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGE 660

Query: 1459 QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATE 1518
             GI       G+  E    G   E    G+               +GI  +    G    
Sbjct: 661  PGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGI 720

Query: 1519 DVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGV 1578
                GI     A G   E    G+   +   G   E  V G++      G   +   QG 
Sbjct: 721  PGQQGIQGHHGAKGERGEKGEPGVRGAIGSKG---ESGVDGLMGPAGPKGQPGDPGPQGP 777

Query: 1579 VNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVA 1638
               D       +E   + +        +   + +  I N D      +Q  + GI     
Sbjct: 778  PGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHC---LSQHGSPGIPGPPG 834

Query: 1639 AHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVAN 1698
              G      + G+   D   G+       G+     + G   E    G        G   
Sbjct: 835  PIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG-------FGYPG 887

Query: 1699 EDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIAN 1752
            E    G    +   G++ E    G   +  + G   +    GI  +    GI +
Sbjct: 888  EQGPPGPPGPEGPPGISKE----GPPGDPGLPGKDGDHGKPGIQGQPGPPGICD 937



 Score = 42.4 bits (98), Expect = 0.006
 Identities = 54/292 (18%), Positives = 86/292 (29%), Gaps = 9/292 (3%)

Query: 1117 QGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANE 1176
            QG+A    V G       +G+       G   +    G+      HG+       G   +
Sbjct: 481  QGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGD 540

Query: 1177 DAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGI 1236
              + G   +   +G        G+       G A E   H       + G   E  + G 
Sbjct: 541  KGSPGFYGKKGAKGEKGNAGFPGLP------GPAGEPGRHGKDGLMGSPGFKGEAGSPGA 594

Query: 1237 ATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAA 1296
              +D   G        G    +   G       QG        G+   +   G      +
Sbjct: 595  PGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGS 654

Query: 1297 QGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANE 1356
            +G   E  +QG+     ++G        G      + GI  +    G   E   QG   E
Sbjct: 655  KGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGE 714

Query: 1357 DAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVA 1408
            +  Q I  +   QGI      +G   E    G+      +G +  D + G A
Sbjct: 715  NGRQGIPGQ---QGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPA 763



 Score = 42.4 bits (98), Expect = 0.006
 Identities = 60/317 (18%), Positives = 100/317 (31%), Gaps = 37/317 (11%)

Query: 1919 QGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANE 1978
            QGI+    V G      A+G+       G   +   +G+      HG+       G   +
Sbjct: 481  QGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGD 540

Query: 1979 DAAQGIAHEDAVQGI---ANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVA 2035
              + G   +   +G    A    + G A E   H         G    + + G   E  +
Sbjct: 541  KGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRH---------GKDGLMGSPGFKGEAGS 591

Query: 2036 DGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQA 2095
             G   +D   G           +P       N G+  +       E    G   ++ A  
Sbjct: 592  PGAPGQDGTRG-----------EPGIPGFPGNRGLMGQK-----GEIGPPGQQGKKGAPG 635

Query: 2096 IAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVA 2155
            +     ++G   +    G        G+     A G+  E  A G   E    G+     
Sbjct: 636  MPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLP---- 691

Query: 2156 AQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVAN 2215
              G+  +   +G   E  +QG   ++  QGI  +   QG+     A G   E    GV  
Sbjct: 692  --GIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQ---QGIQGHHGAKGERGEKGEPGVRG 746

Query: 2216 EVAAQGVANEDAAQGVA 2232
             + ++G +  D   G A
Sbjct: 747  AIGSKGESGVDGLMGPA 763



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 100/517 (19%), Positives = 152/517 (29%), Gaps = 76/517 (14%)

Query: 734  QGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANE 793
            QGIA    V G      + G+     + G   E    G   +  + G      + G   E
Sbjct: 481  QGIAGTPGVPG------SPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGE 534

Query: 794  DAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGV 853
              A G       +G       +G A      G A E   HG      + G   E  + G 
Sbjct: 535  MGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGA 594

Query: 854  TNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGI 913
              +D  +G   E  + G   N               +  +G       QG          
Sbjct: 595  PGQDGTRG---EPGIPGFPGNRGL------------MGQKGEIGPPGQQG---------- 629

Query: 914  AKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQ 973
             K  A G+     +     Q             G+     A G+  E  A G   E    
Sbjct: 630  -KKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYM 688

Query: 974  GVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANED 1033
            G+              +QG   +   QG   +  IQG   E+   GI  +    GI    
Sbjct: 689  GLPG------------IQGKKGDKGNQG---EKGIQGQKGENGRQGIPGQ---QGIQGHH 730

Query: 1034 AAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIA 1093
             A+G   E    G+   + + G   E  V G+      +G   +   QG    D   G  
Sbjct: 731  GAKGERGEKGEPGVRGAIGSKG---ESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGRE 787

Query: 1094 -NEDAVHGVAKEV---------AAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAV 1143
             +E  +  V  +V          +  + N D          + G    +  +G      +
Sbjct: 788  FSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEG---PRGL 844

Query: 1144 QGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAH--EDAVQGIANEDAVHGVA 1201
             G+   D   G+       G+       G   E  +QG  +  E    G    +   G++
Sbjct: 845  PGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGIS 904

Query: 1202 KE--VAAHGVANEDAAHAIAKPDAARGIANEVAAQGI 1236
            KE      G+  +D  H   KP    GI  +    GI
Sbjct: 905  KEGPPGDPGLPGKDGDH--GKP----GIQGQPGPPGI 935



 Score = 42.0 bits (97), Expect = 0.007
 Identities = 88/469 (18%), Positives = 139/469 (29%), Gaps = 37/469 (7%)

Query: 67  GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126
           G+     +QG       +G    D   G        G+     ++G   E+ A+G     
Sbjct: 488 GVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKG---EMGAKGDKGSP 544

Query: 127 AVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIA 186
              G       +G A    + G A E   HG      + G   E  +     +D  +   
Sbjct: 545 GFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTR--- 601

Query: 187 NEDAAQGISKEDAVQGIANE---DAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEV 243
            E    G      + G   E      QG      + G+   +   G       +G   E 
Sbjct: 602 GEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEP 661

Query: 244 EVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIA 303
            +QG+     ++G      + G    +   GI  +   +G   E   QG   E+  QGI 
Sbjct: 662 GIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIP 721

Query: 304 NEDAV---HGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANED 360
            +  +   HG   E    G      A          G+      +G   +    G    D
Sbjct: 722 GQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLD 781

Query: 361 AAHGVAKEVTAHGVAN--EDAVQGVVNEDALHGVVANED------AAQAIAKPDAAHGIA 412
              G  +E +   +     D ++  +      G + N D       +  I  P    G  
Sbjct: 782 GKPG--REFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPE 839

Query: 413 NEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQ 472
                 G+   D   G+       G+     + G   E  +QG        G   E    
Sbjct: 840 GPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGF-------GYPGEQGPP 892

Query: 473 GIANEDAVHGVAKE--VAAHGVANKDAAHAIAKPDAARGIANEVAAQGI 519
           G    +   G++KE      G+  KD  H   KP    GI  +    GI
Sbjct: 893 GPPGPEGPPGISKEGPPGDPGLPGKDGDH--GKP----GIQGQPGPPGI 935



 Score = 41.6 bits (96), Expect = 0.009
 Identities = 68/334 (20%), Positives = 96/334 (28%), Gaps = 15/334 (4%)

Query: 1073 GIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEV 1132
            G+       G+       G   +D   G        GV     +QG      + G   E 
Sbjct: 452  GLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARG---LPGYKGEP 508

Query: 1133 EVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIA 1192
               G   +  + G        G   E+ A G        G       +G A    + G A
Sbjct: 509  GRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPA 568

Query: 1193 NEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAH 1252
             E   HG    + + G   E  +      D  RG   E    G        G   E    
Sbjct: 569  GEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRG---EPGIPGFPGNRGLMGQKGEIGPP 625

Query: 1253 GVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANED 1312
            G   +  A G+       G   +    G        GI     A G+  E    G   E 
Sbjct: 626  GQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEP 685

Query: 1313 PIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGIS 1372
               G+     +QG   +   QG   E    G   E+  QGI  +   Q I     A+G  
Sbjct: 686  GYMGLPG---IQGKKGDKGNQG---EKGIQGQKGENGRQGIPGQ---QGIQGHHGAKGER 736

Query: 1373 KEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQG 1406
             E    G+     ++G +  D + G A      G
Sbjct: 737  GEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPG 770



 Score = 40.8 bits (94), Expect = 0.016
 Identities = 50/250 (20%), Positives = 76/250 (30%), Gaps = 15/250 (6%)

Query: 66  HGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGV---ANEDAAQGVANEVAAQGV 122
           HG+       G   +  + G   +  A G        G+   A E    G    + + G 
Sbjct: 526 HGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGF 585

Query: 123 ANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAA 182
             E    G   +D  +G   E  + G        G   E    G   +  A  +     +
Sbjct: 586 KGEAGSPGAPGQDGTRG---EPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGS 642

Query: 183 QDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANE 242
                +    G        GI     A G+  E    G   E    G+     +QG   +
Sbjct: 643 NGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPG---IQGKKGD 699

Query: 243 VEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGI 302
              QG   E  +QG   E+   GI  +    GI     A+G   E    G+      +G 
Sbjct: 700 KGNQG---EKGIQGQKGENGRQGIPGQ---QGIQGHHGAKGERGEKGEPGVRGAIGSKGE 753

Query: 303 ANEDAVHGVA 312
           +  D + G A
Sbjct: 754 SGVDGLMGPA 763



 Score = 40.4 bits (93), Expect = 0.021
 Identities = 42/203 (20%), Positives = 60/203 (29%), Gaps = 9/203 (4%)

Query: 66  HGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANE 125
           HG        G   E  + G   +D   G   E    G        G   E+   G   +
Sbjct: 574 HGKDGLMGSPGFKGEAGSPGAPGQDGTRG---EPGIPGFPGNRGLMGQKGEIGPPGQQGK 630

Query: 126 DAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKED---AA 182
               G+       G   +    G        GI     A G+  E  A     E      
Sbjct: 631 KGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGL 690

Query: 183 QDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANE 242
             I  +   +G   E  +QG   E+  QGI  +   QG+      +G   E    GV   
Sbjct: 691 PGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQ---QGIQGHHGAKGERGEKGEPGVRGA 747

Query: 243 VEVQGVAHEDAVQGIANEDAAHG 265
           +  +G +  D + G A      G
Sbjct: 748 IGSKGESGVDGLMGPAGPKGQPG 770



 Score = 39.7 bits (91), Expect = 0.036
 Identities = 61/348 (17%), Positives = 97/348 (27%), Gaps = 31/348 (8%)

Query: 1919 QGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANE 1978
            QG   +  + G        G   +   QGIA      G      A G+       G   +
Sbjct: 454  QGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGD 513

Query: 1979 DAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGI 2038
               +G+     + G+       G   +  +        A+G        G+       G 
Sbjct: 514  KGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLP------GP 567

Query: 2039 ANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAK 2098
            A E   HG         +  P       + G   +D   G  E  + G            
Sbjct: 568  AGEPGRHGKDG-----LMGSPGFKGEAGSPGAPGQDGTRG--EPGIPGFPGNRGLMGQKG 620

Query: 2099 QDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQG 2158
            +    G   +  A G+   + + G   +    G        G+     A G+  E  A G
Sbjct: 621  EIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATG 680

Query: 2159 VANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVA 2218
               E    G               + GI  +   +G   E    G   E+  QG+  +  
Sbjct: 681  SPGEPGYMG---------------LPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQ-- 723

Query: 2219 AQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHG 2266
             QG+     A+G   E    GV     ++  +  D   G A      G
Sbjct: 724  -QGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPG 770



 Score = 38.9 bits (89), Expect = 0.061
 Identities = 61/297 (20%), Positives = 91/297 (30%), Gaps = 13/297 (4%)

Query: 219 QGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANE 278
           QG+A    V G       +G+       G   +   +G+      HG+       G   +
Sbjct: 481 QGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGD 540

Query: 279 DAAQGIANEDAAQGIAHEDAVQGI---ANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAA 335
             + G   +  A+G        G+   A E   HG    + + G   E  +      D  
Sbjct: 541 KGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGT 600

Query: 336 HGIANEVATQGIATEDVADGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVAN 395
            G   E    G        G   E    G   +  A G+       G   +    G   +
Sbjct: 601 RG---EPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGS 657

Query: 396 EDAAQAIAKPDAAHGIANEVAAHGIANEDAAQG---IANEVAAHGISKEDAVQGIANEDA 452
           +        P A+ G+  E  A G   E    G   I  +    G   E  +QG   E+ 
Sbjct: 658 KGEPGIQGMPGAS-GLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENG 716

Query: 453 AQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARG 509
            QGI  +   QGI      +G   E    GV   + + G +  D     A P    G
Sbjct: 717 RQGIPGQ---QGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPG 770



 Score = 38.5 bits (88), Expect = 0.080
 Identities = 56/302 (18%), Positives = 88/302 (29%), Gaps = 17/302 (5%)

Query: 228 QGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANE 287
           QG+A    V G       +G+       G   +    G+      HG+       G   +
Sbjct: 481 QGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGD 540

Query: 288 DAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGI 347
             + G   +   +G        G+       G A E   H       + G   E  + G 
Sbjct: 541 KGSPGFYGKKGAKGEKGNAGFPGLP------GPAGEPGRHGKDGLMGSPGFKGEAGSPGA 594

Query: 348 ATEDVADGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDA 407
             +D   G        G    +   G       QG      + G++ +  +      P +
Sbjct: 595 PGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGS 654

Query: 408 AH-----GIANEVAAHGIANEDAAQGIANE---VAAHGISKEDAVQGIANEDAAQGIAHE 459
                  GI     A G+  E  A G   E   +   GI  +   +G   E   QG   E
Sbjct: 655 KGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGE 714

Query: 460 DAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGV---ANKDAAHAIAKPDAARGIANEVAA 516
           +  QGI  +  +QG        G   E    G      +     +  P   +G   +   
Sbjct: 715 NGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGP 774

Query: 517 QG 518
           QG
Sbjct: 775 QG 776



 Score = 38.1 bits (87), Expect = 0.10
 Identities = 85/454 (18%), Positives = 135/454 (29%), Gaps = 51/454 (11%)

Query: 1785 GVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKED 1844
            G+A             ARG+       G   +    G+P     HG+       G   + 
Sbjct: 482  GIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDK 541

Query: 1845 AVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIA 1904
               G   +  A+G                +G A    + G A E   HG      + G  
Sbjct: 542  GSPGFYGKKGAKG---------------EKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFK 586

Query: 1905 NEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAH 1964
             E  +     +D  +G   E  + G        G   E    G   +  A G+   + ++
Sbjct: 587  GEAGSPGAPGQDGTRG---EPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSN 643

Query: 1965 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANED---AAHAIAKPDAARGIA 2021
            G   +    G        GI       G+  E    G   E        I      +G  
Sbjct: 644  GSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQ 703

Query: 2022 NEVAAQGIATEDVADGIANEDAA---HGVANEDAAQAIAKPDAAHGIANEGIATEDVADG 2078
             E   QG   E+   GI  +      HG   E   +   +P     I ++G   E   DG
Sbjct: 704  GEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEK--GEPGVRGAIGSKG---ESGVDG 758

Query: 2079 IAEDA-VQGITNEEAAQAIAKQDAAHG--ITKEDAAQGVTNEVAAQ--------GVANED 2127
            +   A  +G   +   Q     D   G   +++   Q  T+ + AQ         + N D
Sbjct: 759  LMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCD 818

Query: 2128 ---AAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQ 2184
               + HG        G    +  +G+       G+   D V G+       G+     + 
Sbjct: 819  HCLSQHGSPGIPGPPGPIGPEGPRGL------PGLPGRDGVPGLVGVPGRPGVRGLKGLP 872

Query: 2185 GIANEDAAQGVA--NEVAAHGVANEDAAQGVANE 2216
            G   E  +QG     E    G    +   G++ E
Sbjct: 873  GRNGEKGSQGFGYPGEQGPPGPPGPEGPPGISKE 906



 Score = 37.4 bits (85), Expect = 0.18
 Identities = 58/283 (20%), Positives = 82/283 (28%), Gaps = 13/283 (4%)

Query: 563 GIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANED 622
           GI       G   E   DG   +    G+     +HG+       G   +    G   + 
Sbjct: 494 GIQGARGLPGYKGEPGRDG---DKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKK 550

Query: 623 AAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGI 682
            A+G        G+       G   +D L G    +  A +   P    G   E    G 
Sbjct: 551 GAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAP-GQDGTRGEPGIPGF 609

Query: 683 ANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAV 742
                  G   E    G   +  A G+       G   +    G        GI      
Sbjct: 610 PGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGA 669

Query: 743 HGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANE 802
            G+  E  A G   E    G+     +QG   +   QG   E  +QG   E+   GI  +
Sbjct: 670 SGLKGEPGATGSPGEPGYMGLPG---IQGKKGDKGNQG---EKGIQGQKGENGRQGIPGQ 723

Query: 803 VAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVA 845
               G+     A+G   E    GV       G +  D   G A
Sbjct: 724 ---QGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPA 763



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 65/339 (19%), Positives = 97/339 (28%), Gaps = 23/339 (6%)

Query: 227 VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAN 286
           +QG   +  + G        G   +   QGIA      G      A G+       G   
Sbjct: 453 LQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLP------GYKG 506

Query: 287 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQG 346
           E    G   +  + G      + G   E+ A G       +         G A      G
Sbjct: 507 EPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPG 566

Query: 347 IATEDVADGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANED--AAQAIAK 404
            A E    G      + G   E  + G   +D  +G   E  + G   N      +    
Sbjct: 567 PAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRG---EPGIPGFPGNRGLMGQKGEIG 623

Query: 405 PDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQG 464
           P    G        G+   + + G      + G   E  +QG+     A G+  E  A G
Sbjct: 624 PPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMP---GASGLKGEPGATG 680

Query: 465 IAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDV 524
              E    G+       G        G+  +         +  +GI  +   QGI     
Sbjct: 681 SPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKG------ENGRQGIPGQ---QGIQGHHG 731

Query: 525 ADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHG 563
           A G   E    GV   + + G +  D     A P    G
Sbjct: 732 AKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPG 770


>gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo
            sapiens]
          Length = 1691

 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 236/1432 (16%), Positives = 390/1432 (27%), Gaps = 103/1432 (7%)

Query: 202  GIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANED 261
            GI      QG      + G+  E    G+      +G    + V G      + GI    
Sbjct: 56   GIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFL---GINGIPGHP 112

Query: 262  AAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANE--DAVHGVAKEVAAHG 319
               G        G      A G    D   G+     + G      D V          G
Sbjct: 113  GQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKG 172

Query: 320  VANEDAAHAIAKPDAAHGIANEVATQG---IATEDVADGIANEDAAHGVAKEVTAHGVAN 376
                     I  P  A G    V   G   +       G    D   G+       G   
Sbjct: 173  DPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGL-------GFQG 225

Query: 377  EDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAH 436
            E  V+G V      G   +    + +  P    G   E    G        G    +   
Sbjct: 226  EKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGPPGFPG-LGTT 284

Query: 437  GISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKD 496
            G   E   +GI      +G    +  QG   +   +G      ++G        G+  + 
Sbjct: 285  GEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGF------QGIEGQK 338

Query: 497  AAHAIAKPDAARGIANEVAAQGIATEDVAD--GIANEDAVHGVANEVAAHGVANEDAAHA 554
                +  PD    I   V +       V    G+  ++ + G+       G+        
Sbjct: 339  GDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPG 398

Query: 555  IAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDA 614
               P    G+  +    G  T   A G+   D   G            E         + 
Sbjct: 399  ALGPQGFPGLKGDQGNPGRTTIGAA-GLPGRDGLPGPPGPPGPPSPEFET--------ET 449

Query: 615  VHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPD--AAHG 672
            +H    E    G+  E    G      ++G     A  G V N         P      G
Sbjct: 450  LHN--KESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIG 507

Query: 673  IANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDA 732
            +     A G      AQG A      G        G   E  +  I      +G +    
Sbjct: 508  LPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQG 567

Query: 733  VQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANE--------VEVQGIAHE 784
             +G+  E    GV       G+   D  QG   E  + G+  E        +   G+   
Sbjct: 568  FRGVIGEPGKDGVPGLPGLPGLPG-DGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGL 626

Query: 785  DAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGV 844
               +G+  +    G+  +    G         +       G        G        G 
Sbjct: 627  PGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGT 686

Query: 845  AKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGI 904
              +  + G   E    G+V+   L G             P        +G+   + + G+
Sbjct: 687  PGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLP---GKDGLPGMIGSPGL 743

Query: 905  ATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQ 964
                 A G    A +G   E+  Q +         +     +GV  +    G   E  + 
Sbjct: 744  PGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSP 803

Query: 965  GVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHK------------------D 1006
            G   +V   G       +G+  +  + G      + G   K                   
Sbjct: 804  GTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLP 863

Query: 1007 AIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIA 1066
             ++G+       G+     + G+A   A  G   E  + G        G+      +G+ 
Sbjct: 864  GLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLK 923

Query: 1067 NEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQ 1126
                + G        G   E   +G      +    + ++   +  +   QG A  +   
Sbjct: 924  GIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFP 983

Query: 1127 GVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAH-------GIANEDAAQGIANEDAA 1179
            G   +   +G A      G+       GI   V+         GI      +G +     
Sbjct: 984  GPRGD---KGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGF 1040

Query: 1180 QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATE 1239
             G+  E   QGI     + G +      G  +      I+     +G   E   +G    
Sbjct: 1041 PGMPGESGSQGIRGSPGLPGASGLPGLKG--DNGQTVEISGSPGPKGQPGESGFKGTKGR 1098

Query: 1240 DVA------DGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANE 1293
            D         G   ED   GV+ +V   G+       G+A      G+      QG    
Sbjct: 1099 DGLIGNIGFPGNKGEDGKVGVSGDV---GLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGP 1155

Query: 1294 DAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGI 1353
              + G+       G      + G+       G     ++ G+       G   E    GI
Sbjct: 1156 LGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTP-GPSITGVPGPAGLPGPKGEKGYPGI 1214

Query: 1354 A-NEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVE 1412
                     +  +   +G      +QG A    A GI+    + G   +    G+  E  
Sbjct: 1215 GIGAPGKPGLRGQKGDRGF---PGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERG 1271

Query: 1413 VQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIAN 1472
              G A      G ++     G   +    GI      +G        G+  E  ++G+  
Sbjct: 1272 RPGPAGPPGPPGPSSN---QGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRG 1328

Query: 1473 EDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANE----VATQGIATEDVADGIANED 1528
            E    G   +V   G          A P  + G+  +       + +       G+   D
Sbjct: 1329 EPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGID 1388

Query: 1529 AAHGVANEVAAQ---GIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQG 1577
               G+  +  AQ   G+     + G+  +D   G+     A G      +QG
Sbjct: 1389 GIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDPGLPGLQG 1440



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 184/1160 (15%), Positives = 328/1160 (28%), Gaps = 94/1160 (8%)

Query: 1118 GVANEDAVQGVANEVEVQGVAHEDAVQGIAN------EDAAHGIANEVAAHGIANEDAAQ 1171
            G+      QG      + G+  E    G+        +    G+   +  +GI       
Sbjct: 56   GIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGHPGQP 115

Query: 1172 GIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEV 1231
            G        G        G    D   G+       G         +A P + +G+  + 
Sbjct: 116  GPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLA-PGSFKGMKGDP 174

Query: 1232 AAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIA 1291
               G+      DGI     A G    V   G        G+       G    D   G+ 
Sbjct: 175  GLPGL------DGITGPQGAPGFPGAVGPAG------PPGLQGPPGPPGPLGPDGNMGLG 222

Query: 1292 NEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQ 1351
             +   +G+  +  + G A   P  G     E++ +      +G   E    G        
Sbjct: 223  FQ-GEKGVKGDVGLPGPAGPPPSTG-----ELEFMGFPKGKKGSKGEPGPKGFPGISGPP 276

Query: 1352 GIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEV 1411
            G        +   E   +GI      +G    +  QG   +   +G      + G     
Sbjct: 277  GFPGLGTTGE-KGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGF---- 331

Query: 1412 EVQGVAHEDAVQGIANEDAAHGIANEVAAH--GIANEDAAQGIANEDAAQGIAHEDAVQG 1469
              QG+  +    G+   D    I   V +   G        G+  ++  QG+     V G
Sbjct: 332  --QGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPG 389

Query: 1470 IANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAR-----GIANEVATQGIATEDV-ADG 1523
            +     V G        G+  +          AA      G+       G  + +   + 
Sbjct: 390  LPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETET 449

Query: 1524 IANEDAAH-GVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNED 1582
            + N+++   G+  E   +G      + G +   A  G V      G        G++   
Sbjct: 450  LHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLP 509

Query: 1583 ALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGI 1642
             L     +  +  A   P  A G+   +       K   +G       QG+  +    G 
Sbjct: 510  GLKGARGDRGSGGAQG-PAGAPGLVGPLGPSGPKGK---KGEPILSTIQGMPGD---RGD 562

Query: 1643 SKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPV 1702
            S     +G+  E    G+       G+   D  QG   E  + G+  E    G     P 
Sbjct: 563  SGSQGFRGVIGEPGKDGVPGLPGLPGLPG-DGGQGFPGEKGLPGLPGEKGHPGPPGL-PG 620

Query: 1703 QGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHE 1762
             G+      +G+  +    G+  +  + G         I       G        G    
Sbjct: 621  NGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGS 680

Query: 1763 DAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGI 1822
              + G   +        E  + G+ +         P   +G+       G        G 
Sbjct: 681  RGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGS 740

Query: 1823 PNEDAAHGVANEV--AAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHED 1880
            P    + G   ++  A +G   E  +QG+       G +    ++GV  +  + G   E 
Sbjct: 741  PGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGER 800

Query: 1881 AVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQG-I 1939
               G   +    G        GI  +     +       GIS     +G   +    G I
Sbjct: 801  GSPGTPGQVGQPGTPGSSGPYGIKGKSG---LPGAPGFPGISGHPGKKGTRGKKGPPGSI 857

Query: 1940 AKED--AVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 1997
             K+    ++G+       G+     + G+A   A  G   E  + G      + G+    
Sbjct: 858  VKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIP 917

Query: 1998 AVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIA 2057
               G+     +     P    G   E   +G                           + 
Sbjct: 918  GTRGLKGIPGSTGKMGPSGRAGTPGEKGDRG-----------------------NPGPVG 954

Query: 2058 KPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNE 2117
             P     ++N  +  +  + G A     G       +  A +    G+       G+   
Sbjct: 955  IPSPRRPMSNLWLKGDKGSQGSAGS--NGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKG 1012

Query: 2118 VAAQ-------GVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVAN 2170
            V+ +       G+       G +      G+  E  +QG+       G +    ++G   
Sbjct: 1013 VSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNG 1072

Query: 2171 E-VEVQGIAH---KDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANED 2226
            + VE+ G      +    G        G+   +   G   ED   GV+ +V   G     
Sbjct: 1073 QTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFP 1132

Query: 2227 AAQGVANEVAVHGVANEDAA 2246
               G+  E  + G +    A
Sbjct: 1133 GVAGMRGEPGLPGSSGHQGA 1152



 Score = 37.7 bits (86), Expect = 0.14
 Identities = 205/1275 (16%), Positives = 357/1275 (28%), Gaps = 106/1275 (8%)

Query: 1010 GIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANED 1069
            GI       G        G+  E    G+      +G    +   G    + + G   + 
Sbjct: 56   GIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGHPGQP 115

Query: 1070 AAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQG--VANEDAVQG 1127
              +G    D   G       QG        G    +   G+  +   +G  V    + +G
Sbjct: 116  GPRGPPGLDGCNG------TQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKG 169

Query: 1128 VANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDA 1187
            +  +  + G+   D + G        G        G+       G    D   G+  +  
Sbjct: 170  MKGDPGLPGL---DGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGE 226

Query: 1188 VQGIANEDAVHGVAKEVAAHGVAN-------EDAAHAIAKPDAARGIANEVAAQGIATED 1240
             +G+  +  + G A    + G          +  +     P    GI+      G+ T  
Sbjct: 227  -KGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGPPGFPGLGTT- 284

Query: 1241 VADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIA 1300
               G   E    G+       G    + VQG   +   +G      + G       QGI 
Sbjct: 285  ---GEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGF------QGIE 335

Query: 1301 KEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQ 1360
             +    G+   D    +   V + G   +  V G+       GI       G+    A  
Sbjct: 336  GQKGDIGLPGPDVFIDIDGAV-ISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALS 394

Query: 1361 DIANEDAAQGISKEDAVQGIANEDA--AQGIAKEDPVQGVANEDAVQGVANEVEV----- 1413
             +      QG       QG        A G+   D + G            E E      
Sbjct: 395  GVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKE 454

Query: 1414 ---------QGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQG------IANEDAA 1458
                     QG      ++GI  +         V   G   E    G      +     A
Sbjct: 455  SGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGA 514

Query: 1459 QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATE 1518
            +G       QG A    + G        G   E     I      RG +     +G+  E
Sbjct: 515  RGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGE 574

Query: 1519 DVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGV 1578
               DG+       G+  +   QG   E  + G+  E    G    +  +G+      +G+
Sbjct: 575  PGKDGVPGLPGLPGLPGD-GGQGFPGEKGLPGLPGEKGHPGP-PGLPGNGLPGLPGPRGL 632

Query: 1579 VNEDALHSVVANED--AAQAIAKP---DAAHGIANEVAAHSIANKDAAQGIAN---QDAA 1630
              +     +   +    ++ I  P     ++G +             ++G+     Q  +
Sbjct: 633  PGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGS 692

Query: 1631 QGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE 1690
             G   E  + G+     + G       +G+       G+  +D + G+     + G    
Sbjct: 693  SGSKGEPGSPGLVHLPELPGFPGPRGEKGLPG---FPGLPGKDGLPGMIGSPGLPGSKGA 749

Query: 1691 V-----AAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEV 1745
                  A +G   E  +QG+       G +    ++GV  +  + G   E  + G   +V
Sbjct: 750  TGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQV 809

Query: 1746 AAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIA 1805
               G        GI  +  + G      +     +    G                +G  
Sbjct: 810  GQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRG---------------KKGPP 854

Query: 1806 NEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQ 1865
              +  +G+       G+P      G+     + G++   A+ G   E  + G      I 
Sbjct: 855  GSIVKKGLPG---LKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIP 911

Query: 1866 GVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKED 1925
            G+      +G+       G        G   E   +G              +   +  + 
Sbjct: 912  GLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDK 971

Query: 1926 AVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIA 1985
              QG A  +   G   +   +G A      G+       GI       G        GI 
Sbjct: 972  GSQGSAGSNGFPGPRGD---KGEAGRPGPPGLPGAPGLPGIIK--GVSGKPGPPGFMGIR 1026

Query: 1986 HEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAH 2045
                ++G +      G+  E  +  I       G +     +G   + V   I+      
Sbjct: 1027 GLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVE--ISGSPGPK 1084

Query: 2046 GVANEDAAQAIAKPDAAHG-IANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHG 2104
            G   E   +     D   G I   G   ED   G++ D   G+        +A      G
Sbjct: 1085 GQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDV--GLPGAPGFPGVAGMRGEPG 1142

Query: 2105 ITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDA 2164
            +      QG    + + G+       G       +G+       G     +  GV     
Sbjct: 1143 LPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGP-SITGVPGPAG 1201

Query: 2165 VQGVANEVEVQGIA----HKDAIQGIANE---DAAQGVANEVAAHGVANEDAAQGVANEV 2217
            + G   E    GI      K  ++G   +      QG A    A G++      G   + 
Sbjct: 1202 LPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDP 1261

Query: 2218 AAQGVANEDAAQGVA 2232
               G+  E    G A
Sbjct: 1262 GRPGLDGERGRPGPA 1276



 Score = 37.0 bits (84), Expect = 0.23
 Identities = 198/1221 (16%), Positives = 328/1221 (26%), Gaps = 83/1221 (6%)

Query: 965  GVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEV 1024
            G   E   +G+       G    + VQG   +   QG   K    G    +   GI  + 
Sbjct: 285  GEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQ---QG---KKGTLGFPGLNGFQGIEGQK 338

Query: 1025 AAHGIANEDAAQGI--ANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQG 1082
               G+   D    I  A      G        G+  ++ +QG+       G+       G
Sbjct: 339  GDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPG 398

Query: 1083 IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDA 1142
                    G+  +    G    + A G+   D + G            E E     H   
Sbjct: 399  ALGPQGFPGLKGDQGNPG-RTTIGAAGLPGRDGLPGPPGPPGPPSPEFETET---LHN-- 452

Query: 1143 VQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAK 1202
                  E    G+  E    G       +G +   A  G        G        G+  
Sbjct: 453  -----KESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIG 507

Query: 1203 EVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHG 1262
                 G   +  +     P  A G+   +   G        G   E     +       G
Sbjct: 508  LPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSG------PKGKKGEPILSTIQGMPGDRG 561

Query: 1263 ISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVE 1322
             S     +G+  E    G+     + G+   D  QG   E  + G+  E    G    + 
Sbjct: 562  DSGSQGFRGVIGEPGKDGVPGLPGLPGLPG-DGGQGFPGEKGLPGLPGEKGHPGPPG-LP 619

Query: 1323 VQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIAN 1382
              G+      +G+  +    G+  +    G         I       G        G   
Sbjct: 620  GNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKG 679

Query: 1383 EDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAH---EDAVQGIANEDAAHGIANEVA 1439
                 G   +    G   E    G+ +  E+ G      E  + G        G+   + 
Sbjct: 680  SRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIG 739

Query: 1440 AHGIANEDAAQG--IANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAI 1497
            + G+     A G     E+ A G   E  +QG+       G +      GV  +      
Sbjct: 740  SPGLPGSKGATGDIFGAENGAPG---EQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGP 796

Query: 1498 AKPDAARGIANEVATQGIATEDVADGIANEDAAHG------VANEVAAQGIANEVAVHGV 1551
                 + G   +V   G        GI  +    G      ++     +G   +    G 
Sbjct: 797  KGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGS 856

Query: 1552 AIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVA 1611
             ++  + G+       G+     + G+        V        A++ P    G    V 
Sbjct: 857  IVKKGLPGL------KGLPGNPGLVGLKGSPGSPGVAG----LPALSGPKGEKGSVGFVG 906

Query: 1612 AHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAH 1671
               I       G        G   ++   G +     +G        GI +         
Sbjct: 907  FPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLW 966

Query: 1672 EDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQG 1731
                +G       +G        G A      G+     + G+   V   G        G
Sbjct: 967  LKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVS--GKPGPPGFMG 1024

Query: 1732 IANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHS----VAKEVAAHGVA 1787
            I       G +      G+  E  +QGI     + G +    +        +   + G  
Sbjct: 1025 IRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPK 1084

Query: 1788 NEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQ 1847
             +             G+   +   G   ED   G+  +    G        G+  E  + 
Sbjct: 1085 GQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLP 1144

Query: 1848 GIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANED 1907
            G +    A G      + G        G+     + G+      HG        G+    
Sbjct: 1145 GSSGHQGAIGPLGSPGLIGPKGFPGFPGL---HGLNGLPGTKGTHGTPGPSIT-GVPGPA 1200

Query: 1908 AAQDIANEDAAQGIS-KEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGI 1966
                   E    GI        G+  Q   +G      +QG A    A GI+      G 
Sbjct: 1201 GLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFP---GLQGPAGLPGAPGISLPSLIAGQ 1257

Query: 1967 ANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAA 2026
              +    G+  E    G A      G ++     G   +     I  P   +G       
Sbjct: 1258 PGDPGRPGLDGERGRPGPAGPPGPPGPSSNQ---GDTGDPGFPGIPGPKGPKGDQGIPGF 1314

Query: 2027 QGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQG 2086
             G+  E    G+  E    G   +     +  P        +G A    + G+  D  Q 
Sbjct: 1315 SGLPGELGLKGMRGEPGFMGTPGK-----VGPPGDPGFPGMKGKAGPRGSSGLQGDPGQT 1369

Query: 2087 ITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDA 2146
             T    A+A+       G+   D   G+T +  AQG      + G+       G+  +D 
Sbjct: 1370 PT----AEAVQVPPGPLGLPGIDGIPGLTGDPGAQGPVGLQGSKGLP------GIPGKDG 1419

Query: 2147 AQGVANEVAAQGVANEDAVQG 2167
              G+     A G      +QG
Sbjct: 1420 PSGLPGPPGALGDPGLPGLQG 1440



 Score = 36.2 bits (82), Expect = 0.39
 Identities = 129/790 (16%), Positives = 223/790 (28%), Gaps = 62/790 (7%)

Query: 67   GITNEDAVQGVANEVAAQGVANEDAAHGVANEV--AAHGVANEDAAQGVANEVAAQGVAN 124
            G+  +D + G+       G      + G   ++  A +G   E   QG+       G + 
Sbjct: 727  GLPGKDGLPGMIGSPGLPG------SKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSG 780

Query: 125  EDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQD 184
               ++GV  +  + G   E    G   +    G        GI  +              
Sbjct: 781  LPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSG------------ 828

Query: 185  IANEDAAQGISKEDAVQGIANEDAAQG--IAKEDP-VQGVANEDPVQGVANEDAVQGVAN 241
            +       GIS     +G   +    G  + K  P ++G+     + G+       GVA 
Sbjct: 829  LPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAG 888

Query: 242  EVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQG 301
               + G   E    G        G+       G+     + G        G   E   +G
Sbjct: 889  LPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRG 948

Query: 302  IANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDA 361
                  +    + ++   +  +  +   A    ++G       +G A      G+     
Sbjct: 949  NPGPVGIPSPRRPMSNLWLKGDKGSQGSA---GSNGFPGPRGDKGEAGRPGPPGLPGAPG 1005

Query: 362  AHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKP--DAAHGIANEVAAHG 419
              G+ K     GV+ +    G +    L G+  +         P    + GI       G
Sbjct: 1006 LPGIIK-----GVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPG 1060

Query: 420  IANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDA 479
             +     +G   +     IS     +G   E   +G    D   G+       G   ED 
Sbjct: 1061 ASGLPGLKGDNGQTVE--ISGSPGPKGQPGESGFKGTKGRD---GLIGNIGFPGNKGEDG 1115

Query: 480  VHGVAKEVAA------HGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDA 533
              GV+ +V         GVA       +      +G    + + G+       G      
Sbjct: 1116 KVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHG 1175

Query: 534  VHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAN 593
            ++G+      HG         +  P    G   E    GI     A G        G   
Sbjct: 1176 LNGLPGTKGTHGTPGPSIT-GVPGPAGLPGPKGEKGYPGIGIG--APGKPGLRGQKGDRG 1232

Query: 594  EVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHG 653
               + G A      G++    + G   +    G+  E    G A      G  +     G
Sbjct: 1233 FPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTG 1292

Query: 654  VVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKED 713
                +     I  P    G        G+  E   +G+  E    G   +V   G     
Sbjct: 1293 ----DPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFP 1348

Query: 714  AVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVA 773
             ++G A    + G+  +              V       G+   D + G+  +   QG  
Sbjct: 1349 GMKGKAGPRGSSGLQGDP-----GQTPTAEAVQVPPGPLGLPGIDGIPGLTGDPGAQGPV 1403

Query: 774  NEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVH 833
                  G+     + GI  +D   G+     A G       QG    + A G      + 
Sbjct: 1404 ------GLQGSKGLPGIPGKDGPSGLPGPPGALGDPGLPGLQGPPGFEGAPGQQGPFGMP 1457

Query: 834  GVANEDAAQG 843
            G+  +    G
Sbjct: 1458 GMPGQSMRVG 1467


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.305    0.122    0.325 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 71,364,975
Number of Sequences: 37866
Number of extensions: 2848421
Number of successful extensions: 23601
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 79
Number of HSP's that attempted gapping in prelim test: 5861
Number of HSP's gapped (non-prelim): 3069
length of query: 2378
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2259
effective length of database: 13,741,464
effective search space: 31041967176
effective search space used: 31041967176
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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