BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239757639 PREDICTED: similar to collagen, type I, alpha 2 [Homo sapiens] (2378 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239757639 PREDICTED: similar to collagen, type I, alpha 2 [Ho... 4566 0.0 gi|239746652 PREDICTED: hypothetical protein [Homo sapiens] 2160 0.0 gi|239752511 PREDICTED: hypothetical protein, partial [Homo sapi... 694 0.0 gi|239746643 PREDICTED: hypothetical protein [Homo sapiens] 367 e-100 gi|239746650 PREDICTED: hypothetical protein [Homo sapiens] 362 2e-99 gi|239746623 PREDICTED: hypothetical protein [Homo sapiens] 359 2e-98 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 125 6e-28 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 125 6e-28 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 114 1e-24 gi|48762934 alpha 2 type I collagen [Homo sapiens] 100 2e-20 gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 100 2e-20 gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 100 3e-20 gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 100 3e-20 gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 100 3e-20 gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 99 6e-20 gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 99 6e-20 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 91 1e-17 gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens] 88 1e-16 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 87 3e-16 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 85 1e-15 gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 83 3e-15 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 81 1e-14 gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 77 2e-13 gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 69 5e-11 gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 64 2e-09 gi|5803080 macrophage receptor with collagenous structure [Homo ... 59 4e-08 gi|11386161 alpha 2 type IX collagen [Homo sapiens] 57 2e-07 gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] 57 2e-07 gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens] 57 3e-07 gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo ... 54 2e-06 >gi|239757639 PREDICTED: similar to collagen, type I, alpha 2 [Homo sapiens] Length = 2378 Score = 4566 bits (11843), Expect = 0.0 Identities = 2378/2378 (100%), Positives = 2378/2378 (100%) Query: 1 MITTKHKRNQILQATSSEESLVHKDRGDGERPVNVRVVQVAPLRHESTPYEDTVHDIANE 60 MITTKHKRNQILQATSSEESLVHKDRGDGERPVNVRVVQVAPLRHESTPYEDTVHDIANE Sbjct: 1 MITTKHKRNQILQATSSEESLVHKDRGDGERPVNVRVVQVAPLRHESTPYEDTVHDIANE 60 Query: 61 DADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQ 120 DADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQ Sbjct: 61 DADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQ 120 Query: 121 GVANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKED 180 GVANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKED Sbjct: 121 GVANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKED 180 Query: 181 AAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVA 240 AAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVA Sbjct: 181 AAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVA 240 Query: 241 NEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQ 300 NEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQ Sbjct: 241 NEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQ 300 Query: 301 GIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANED 360 GIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANED Sbjct: 301 GIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANED 360 Query: 361 AAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGI 420 AAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGI Sbjct: 361 AAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGI 420 Query: 421 ANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAV 480 ANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAV Sbjct: 421 ANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAV 480 Query: 481 HGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANE 540 HGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANE Sbjct: 481 HGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANE 540 Query: 541 VAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGV 600 VAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGV Sbjct: 541 VAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGV 600 Query: 601 AIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDA 660 AIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDA Sbjct: 601 AIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDA 660 Query: 661 AQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIAN 720 AQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIAN Sbjct: 661 AQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIAN 720 Query: 721 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQG 780 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQG Sbjct: 721 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQG 780 Query: 781 IAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDA 840 IAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDA Sbjct: 781 IAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDA 840 Query: 841 AQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVA 900 AQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVA Sbjct: 841 AQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVA 900 Query: 901 AQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANE 960 AQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANE Sbjct: 901 AQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANE 960 Query: 961 DAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGI 1020 DAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGI Sbjct: 961 DAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGI 1020 Query: 1021 ANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAA 1080 ANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAA Sbjct: 1021 ANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAA 1080 Query: 1081 QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHE 1140 QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHE Sbjct: 1081 QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHE 1140 Query: 1141 DAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1200 DAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV Sbjct: 1141 DAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1200 Query: 1201 AKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAA 1260 AKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAA Sbjct: 1201 AKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAA 1260 Query: 1261 HGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANE 1320 HGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANE Sbjct: 1261 HGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANE 1320 Query: 1321 VEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGI 1380 VEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGI Sbjct: 1321 VEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGI 1380 Query: 1381 ANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAA 1440 ANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAA Sbjct: 1381 ANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAA 1440 Query: 1441 HGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKP 1500 HGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKP Sbjct: 1441 HGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKP 1500 Query: 1501 DAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGV 1560 DAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGV Sbjct: 1501 DAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGV 1560 Query: 1561 VKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDA 1620 VKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDA Sbjct: 1561 VKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDA 1620 Query: 1621 AQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIAN 1680 AQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIAN Sbjct: 1621 AQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIAN 1680 Query: 1681 EDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHG 1740 EDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHG Sbjct: 1681 EDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHG 1740 Query: 1741 ITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDA 1800 ITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDA Sbjct: 1741 ITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDA 1800 Query: 1801 ARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAK 1860 ARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAK Sbjct: 1801 ARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAK 1860 Query: 1861 EDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQG 1920 EDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQG Sbjct: 1861 EDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQG 1920 Query: 1921 ISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDA 1980 ISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDA Sbjct: 1921 ISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDA 1980 Query: 1981 AQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIAN 2040 AQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIAN Sbjct: 1981 AQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIAN 2040 Query: 2041 EDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQD 2100 EDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQD Sbjct: 2041 EDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQD 2100 Query: 2101 AAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVA 2160 AAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVA Sbjct: 2101 AAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVA 2160 Query: 2161 NEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQ 2220 NEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQ Sbjct: 2161 NEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQ 2220 Query: 2221 GVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVHGIANED 2280 GVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVHGIANED Sbjct: 2221 GVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVHGIANED 2280 Query: 2281 AVYDIANDTVQGTLTRTLYRTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLM 2340 AVYDIANDTVQGTLTRTLYRTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLM Sbjct: 2281 AVYDIANDTVQGTLTRTLYRTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLM 2340 Query: 2341 RAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDTV 2378 RAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDTV Sbjct: 2341 RAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDTV 2378 >gi|239746652 PREDICTED: hypothetical protein [Homo sapiens] Length = 1513 Score = 2160 bits (5596), Expect = 0.0 Identities = 1166/1407 (82%), Positives = 1203/1407 (85%), Gaps = 129/1407 (9%) Query: 1085 HEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQ 1144 +ED V IANEDA D G+ NEDAVQGVANEV QGVA+EDA Sbjct: 123 YEDTVHDIANEDA----------------DAAHGITNEDAVQGVANEVAAQGVANEDAAH 166 Query: 1145 GIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEV 1204 G+ANE AAHG+ANE AA G+ANE AAQG+ANEDAAQG+A+EDAVQG+ANEDA HG+A EV Sbjct: 167 GVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEDAVQGVANEDAAHGIANEV 226 Query: 1205 AAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGIS 1264 AAHGVANEDAA +A DAA+G+ANE A G+A ED A G+A E AHGV NE A G+ Sbjct: 227 AAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVV 286 Query: 1265 KEDAVQGI-ANEDAAQGIAK-------------------------------EDAVQGIAN 1292 ++A+ G+ ANEDAAQ IAK EDA GI N Sbjct: 287 NQEALHGVVANEDAAQAIAKPDSAHGIANEGVANEVAAQGIATEDVADGIAEDAAHGITN 346 Query: 1293 EDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQG 1352 E+AAQ IAK+D + NED +QGVANE GVA+EDA QGIANE A HGI+ EDA QG Sbjct: 347 EEAAQAIAKQDAAHSITNEDAVQGVANEDAAHGVANEDAAQGIANEVATHGISKEDAVQG 406 Query: 1353 IANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKE---------DPVQGVANEDA 1403 IANEDAAQ IANEDAAQGI+ EDAVQGIANEDA G+AKE DPVQGVANEDA Sbjct: 407 IANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDA 466 Query: 1404 VQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAH 1463 VQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAH Sbjct: 467 VQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAH 526 Query: 1464 EDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADG 1523 EDAVQGIANEDAVHG+AKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIAT+DVADG Sbjct: 527 EDAVQGIANEDAVHGIAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATQDVADG 586 Query: 1524 IANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDA 1583 IANEDAAHGVANEVAA GIANEVAVH VAIEDA QGV KEVTAHGVANEDAVQGVVNE A Sbjct: 587 IANEDAAHGVANEVAAHGIANEVAVHCVAIEDAAQGVAKEVTAHGVANEDAVQGVVNEYA 646 Query: 1584 LHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGIS 1643 LHSVVANEDAAQAIAKPDAAHGIANEVAAHSIAN+DAAQGIAN+DAAQGIANEVAAHGIS Sbjct: 647 LHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANEDAAQGIANEDAAQGIANEVAAHGIS 706 Query: 1644 KEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQ 1703 KEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQ Sbjct: 707 KEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQ 766 Query: 1704 GVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAH---------GIANED 1754 GVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAH GIANED Sbjct: 767 GVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANED 826 Query: 1755 AAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIA 1814 AAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIA Sbjct: 827 AAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIA 886 Query: 1815 TEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQ 1874 TEDVADGI NEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQ Sbjct: 887 TEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQ 946 Query: 1875 GVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQD 1934 GVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGI+KED VQG+AN+D Sbjct: 947 GVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGIAKEDPVQGVANED 1006 Query: 1935 AAQGIAK------------------EDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIA 1976 QG+A EDAVQGIANEDAA GIANEVAAHGIANEDAAQGIA Sbjct: 1007 PVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIA 1066 Query: 1977 NEDAAQGIAHEDAVQGIANEDAV---------HGVANEDAAHAIAKPDAARGIANEVAAQ 2027 NEDAAQGIAHEDAVQGIANEDAV HGVANEDAAHAIAKPDAARGIANEVAAQ Sbjct: 1067 NEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQ 1126 Query: 2028 GIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANE---------GIATEDVADG 2078 GIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANE GIATEDVADG Sbjct: 1127 GIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADG 1186 Query: 2079 IAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAA 2138 IAEDAVQGITNEEAAQAIAKQDAAHGIT EDAAQGVTNEVAAQGVANEDAAHGVANEVAA Sbjct: 1187 IAEDAVQGITNEEAAQAIAKQDAAHGITNEDAAQGVTNEVAAQGVANEDAAHGVANEVAA 1246 Query: 2139 HGVANEDAAQGVANEVAAQ---------GVANEDAVQGVANEVEVQGIAHKDAIQGI--- 2186 HGVANEDAAQGVANEVAAQ GVANEDAVQGVANEVEVQGIAHKDAIQGI Sbjct: 1247 HGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANE 1306 Query: 2187 ------ANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGV 2240 ANEDAAQGVANEVAAHGVANEDAA GVANEVAAQGVANEDAAQGVANEVAVHGV Sbjct: 1307 DAAQGVANEDAAQGVANEVAAHGVANEDAAHGVANEVAAQGVANEDAAQGVANEVAVHGV 1366 Query: 2241 ANEDAARHMAKEDAAQGIANEDAAHGIANEDAVH---------GIANEDAVYDIANDTVQ 2291 ANEDAARHMAKEDAAQ IANEDAAHGIANEDAVH GIANEDAVYDIANDTVQ Sbjct: 1367 ANEDAARHMAKEDAAQDIANEDAAHGIANEDAVHGIANEDSVYGIANEDAVYDIANDTVQ 1426 Query: 2292 GTLTRTLYRTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMRAPYKTSPMRA 2351 GTLTRTLYRTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMRAPYKTSPMRA Sbjct: 1427 GTLTRTLYRTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMRAPYKTSPMRA 1486 Query: 2352 LYTTLLMIPTRHANADTVHDIANEDTV 2378 LYTTLLMIPTRHANADTVHDIANEDTV Sbjct: 1487 LYTTLLMIPTRHANADTVHDIANEDTV 1513 Score = 1807 bits (4680), Expect = 0.0 Identities = 971/1330 (73%), Positives = 1047/1330 (78%), Gaps = 54/1330 (4%) Query: 467 HEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVAD 526 +ED V IANEDA DAAH I DA +G+ANEVAAQG+A ED A Sbjct: 123 YEDTVHDIANEDA----------------DAAHGITNEDAVQGVANEVAAQGVANEDAAH 166 Query: 527 GIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANED 586 G+ANE A HGVANE AA GVANE AA +A DAA G+ANE A QG+A ED A GIANE Sbjct: 167 GVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEDAVQGVANEDAAHGIANEV 226 Query: 587 AAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVV 646 AAHGVANE A GVA EDA QGVANEDAVHGVANEDAAQG+AKEVTAHGV NEDAVQGVV Sbjct: 227 AAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVV 286 Query: 647 NEDALHGVVANEDAAQAIAKPDAAHGIANE-----VAAHGIANEDAAQGIANEDAAQGIA 701 N++ALHGVVANEDAAQAIAKPD+AHGIANE VAA GIA ED A GIA EDAA GI Sbjct: 287 NQEALHGVVANEDAAQAIAKPDSAHGIANEGVANEVAAQGIATEDVADGIA-EDAAHGIT 345 Query: 702 NEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQ 761 NE AA I+K+DA I NEDA QG+A+EDA G+ANEDA G+A EVA HG++ ED VQ Sbjct: 346 NEEAAQAIAKQDAAHSITNEDAVQGVANEDAAHGVANEDAAQGIANEVATHGISKEDAVQ 405 Query: 762 GVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANED 821 G+ANED QG+ANE QGIAHEDAVQGIANEDA HG+A EVAAHGVANED QGVANED Sbjct: 406 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANED 465 Query: 822 AAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAI 881 A QGVANE V GVA+EDA QG+A E AHG+ NE A G+ NE+A G+ ANEDAAQ I Sbjct: 466 AVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGI-ANEDAAQGI 524 Query: 882 AKPDAAHGIANE----GVANEVAAQGIATEDVADGIAK-DAAHGITKEEAAQAIAKQDAA 936 A DA GIANE G+A EVAA G+A ED A IAK DAA GI E A Q IA QD A Sbjct: 525 AHEDAVQGIANEDAVHGIAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATQDVA 584 Query: 937 HSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANE 996 I NEDAA GVANE AAHG+ANE A VA E AAQGVA E HGVANEDAVQGV NE Sbjct: 585 DGIANEDAAHGVANEVAAHGIANEVAVHCVAIEDAAQGVAKEVTAHGVANEDAVQGVVNE 644 Query: 997 VEVQGI-AHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHG 1055 + + A++DA Q IA DAAHGIANEVAAH IANEDAAQGIANEDAAQGIANEVAAHG Sbjct: 645 YALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANEDAAQGIANEDAAQGIANEVAAHG 704 Query: 1056 ISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDP 1115 ISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDP Sbjct: 705 ISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDP 764 Query: 1116 VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIAN 1175 VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGI NEVAAHGIANEDAAQGIAN Sbjct: 765 VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAN 824 Query: 1176 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQG 1235 EDAAQGIAHEDAVQGIANEDAVH VAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQG Sbjct: 825 EDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQG 884 Query: 1236 IATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDA 1295 IATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKED +QG+ANE Sbjct: 885 IATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVE 944 Query: 1296 AQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIAN 1355 QG+A ED VQG+ANED G+ANE QG+A+EDA Q IANEDAA GIA ED QG+AN Sbjct: 945 VQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGIAKEDPVQGVAN 1004 Query: 1356 EDAAQDIANEDAAQGISK---------EDAVQGIANEDAAQGIAKEDPVQGVANEDAVQG 1406 ED Q +ANEDA QG++ EDAVQGIANEDAA GIA E G+ANEDA QG Sbjct: 1005 EDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQG 1064 Query: 1407 VANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDA 1466 +ANE QG+AHEDAVQGIANEDA HG+A EVAAHG+ANEDAA IA DAA+GIA+E A Sbjct: 1065 IANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVA 1124 Query: 1467 VQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGI-----ANEVATQGIATEDVA 1521 QGIA ED G+A E AAHGVANEDAA AIAKPDAA GI ANEVA QGIATEDVA Sbjct: 1125 AQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVA 1184 Query: 1522 DGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNE 1581 DGIA EDA G+ NE AAQ IA + A HG+ EDA QGV EV A GVANEDA GV NE Sbjct: 1185 DGIA-EDAVQGITNEEAAQAIAKQDAAHGITNEDAAQGVTNEVAAQGVANEDAAHGVANE 1243 Query: 1582 DALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHG 1641 A H VANEDAAQ G+ANEVAA +AN+DA G+AN+DA QG+ANEV G Sbjct: 1244 VAAHG-VANEDAAQ---------GVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQG 1293 Query: 1642 ISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDP 1701 I+ +DA+QGIANEDAAQG+ANEDAAQG+A+E A G+ANEDA HGVA EVAA GVANED Sbjct: 1294 IAHKDAIQGIANEDAAQGVANEDAAQGVANEVAAHGVANEDAAHGVANEVAAQGVANEDA 1353 Query: 1702 VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAH 1761 QGVANE AV GVANE + +A EDA Q IANEDAAHGI NE A HGIANED+ GIA+ Sbjct: 1354 AQGVANEVAVHGVANEDAARHMAKEDAAQDIANEDAAHGIANEDAVHGIANEDSVYGIAN 1413 Query: 1762 EDAVQGIANE 1771 EDAV IAN+ Sbjct: 1414 EDAVYDIAND 1423 Score = 1613 bits (4177), Expect = 0.0 Identities = 896/1341 (66%), Positives = 966/1341 (72%), Gaps = 222/1341 (16%) Query: 16 SSEESLVHKDRGDGERPVNVRVVQVAPLRHESTPYEDTVHDIANEDADAAHGITNEDAVQ 75 +SEESLVHKDRGDGERPVNVRVVQVAPLRHESTPYEDTVHDIANEDADAAHGITNEDAVQ Sbjct: 89 ASEESLVHKDRGDGERPVNVRVVQVAPLRHESTPYEDTVHDIANEDADAAHGITNEDAVQ 148 Query: 76 GVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANED 135 GVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDA QGVANED Sbjct: 149 GVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANED 208 Query: 136 AVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQGIS 195 AVQGVANEDA GIANE AAHG+ANEDAAQG+ANEDAAQ +A EDA +ANEDAAQG++ Sbjct: 209 AVQGVANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVA 268 Query: 196 K---------EDAVQG----------IANEDAAQGIAKEDPVQGVANE------------ 224 K EDAVQG +ANEDAAQ IAK D G+ANE Sbjct: 269 KEVTAHGVTNEDAVQGVVNQEALHGVVANEDAAQAIAKPDSAHGIANEGVANEVAAQGIA 328 Query: 225 ----------------------------DPVQGVANEDAVQGVANEVEVQGVAHEDAVQG 256 D + NEDAVQGVANE GVA+EDA QG Sbjct: 329 TEDVADGIAEDAAHGITNEEAAQAIAKQDAAHSITNEDAVQGVANEDAAHGVANEDAAQG 388 Query: 257 IANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVA 316 IANE A HGI+ E A GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVA Sbjct: 389 IANEVATHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVA 448 Query: 317 AHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKEVTAHGVAN 376 AHGVANED +A DA G+ANEV QG+A ED GIANEDAAHG+A EV AHG+AN Sbjct: 449 AHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIAN 508 Query: 377 ------------------EDAVQGVVNEDALHGV--------VANEDAAQAIAKPDAAHG 410 EDAVQG+ NEDA+HG+ VANEDAA AIAKPDAA G Sbjct: 509 EDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGIAKEVAAHGVANEDAAHAIAKPDAARG 568 Query: 411 IANEVA---------AHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDA 461 IANEVA A GIANEDAA G+ANEVAAHGI+ E AV +A EDAAQG+A E Sbjct: 569 IANEVATQGIATQDVADGIANEDAAHGVANEVAAHGIANEVAVHCVAIEDAAQGVAKEVT 628 Query: 462 AQGIAHEDAVQGIANE-------------------DAVHGVAKEVAAHGVANKDAAHAIA 502 A G+A+EDAVQG+ NE DA HG+A EVAAH +AN+DAA IA Sbjct: 629 AHGVANEDAVQGVVNEYALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANEDAAQGIA 688 Query: 503 KPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAH 562 DAA+GIANEVAA GI+ ED GIANEDA G+ANE AA G+A+EDA IA DA H Sbjct: 689 NEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVH 748 Query: 563 GIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANED--------- 613 G+A EVA G+A ED G+ANEDA GVANEV V GVA EDAVQG+ANED Sbjct: 749 GVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEV 808 Query: 614 AVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGV--------VANEDAAQAIA 665 A HG+ANEDAAQGIA E A G+A+EDAVQG+ NEDA+H V VANEDAA AIA Sbjct: 809 AAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIA 868 Query: 666 KPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQ 725 KPDAA GIANEVAA GIA ED A GIANEDAA G+ANEVAAHGISKEDAVQGIANEDAAQ Sbjct: 869 KPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQ 928 Query: 726 GI------------------AHEDAVQGIANEDAVHGVAKEVAA---------------- 751 GI AHEDAVQGIANEDA HG+A E AA Sbjct: 929 GIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANED 988 Query: 752 -----------HGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIA 800 GVANEDPVQGVANED VQGVANEVEVQG+AHEDAVQGIANEDAAHGIA Sbjct: 989 AAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIA 1048 Query: 801 NEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDA-- 858 NEVAAHG+ANEDAAQG+ANEDAAQG+A+EDAV G+ANEDA GVAKEV AHGV NEDA Sbjct: 1049 NEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAH 1108 Query: 859 -------------------------VQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANE 893 G+ NE+A HG VANEDAAQAIAKPDAAHGIANE Sbjct: 1109 AIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHG-VANEDAAQAIAKPDAAHGIANE 1167 Query: 894 GVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQ------- 946 GVANEVAAQGIATEDVADGIA+DA GIT EEAAQAIAKQDAAH ITNEDAAQ Sbjct: 1168 GVANEVAAQGIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITNEDAAQGVTNEVA 1227 Query: 947 -----------GVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVAN 995 GVANE AAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVAN Sbjct: 1228 AQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVAN 1287 Query: 996 EVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHG 1055 EVEVQGIAHKDAIQGIANEDAA G+ANE AA G+ANE AA G+ANEDAA G+ANEVAA G Sbjct: 1288 EVEVQGIAHKDAIQGIANEDAAQGVANEDAAQGVANEVAAHGVANEDAAHGVANEVAAQG 1347 Query: 1056 ISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDP 1115 ++ EDA QG+ANE A G+ANEDAA+ +A EDA Q IANEDA HG+A E A HG+ANED Sbjct: 1348 VANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQDIANEDAAHGIANEDAVHGIANEDS 1407 Query: 1116 VQGVANEDAVQGVANEVEVQG 1136 V G+ANEDAV +AN+ VQG Sbjct: 1408 VYGIANEDAVYDIANDT-VQG 1427 Score = 1278 bits (3308), Expect = 0.0 Identities = 698/1055 (66%), Positives = 774/1055 (73%), Gaps = 114/1055 (10%) Query: 1324 QGVAHEDAVQGIANE--DAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIA 1381 + +ED V IANE DAAHGI NEDA QG+ANE AAQ +ANEDAA G++ E A G+A Sbjct: 119 ESTPYEDTVHDIANEDADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVA 178 Query: 1382 NEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAH 1441 NEDAAQG+A E QGVANEDA QGVAN EDAVQG+ANEDAAHGIANEVAAH Sbjct: 179 NEDAAQGVANEVAAQGVANEDAAQGVAN---------EDAVQGVANEDAAHGIANEVAAH 229 Query: 1442 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHG-------------- 1487 G+ANEDAAQG+ANEDAAQG+A+EDAV G+ANEDA GVAKEV AHG Sbjct: 230 GVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNQE 289 Query: 1488 -----VANEDAAHAIAKPDAARGI-----ANEVATQGIATEDVADGIANEDAAHGVANEV 1537 VANEDAA AIAKPD+A GI ANEVA QGIATEDVADGIA EDAAHG+ NE Sbjct: 290 ALHGVVANEDAAQAIAKPDSAHGIANEGVANEVAAQGIATEDVADGIA-EDAAHGITNEE 348 Query: 1538 AA------------------QGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVV 1579 AA QG+ANE A HGVA EDA QG+ EV HG++ EDAVQG+ Sbjct: 349 AAQAIAKQDAAHSITNEDAVQGVANEDAAHGVANEDAAQGIANEVATHGISKEDAVQGIA 408 Query: 1580 NEDALHSV--------VANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQ 1631 NEDA + +A+EDA Q IA DA HG+A EVAAH +AN+D QG+AN+DA Q Sbjct: 409 NEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQ 468 Query: 1632 GIANEV------------------AAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHED 1673 G+ANEV AAHGI+ E A GIANEDAAQGIANEDAAQGIAHED Sbjct: 469 GVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHED 528 Query: 1674 AVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIA 1733 AVQGIANEDAVHG+AKEVAAHGVANED +A DA +G+ANEV QG+A +D GIA Sbjct: 529 AVQGIANEDAVHGIAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATQDVADGIA 588 Query: 1734 NEDAAHGITNEVAAHGIAN---------EDAAQGIAHEDAVQGIANEDAVHSVAKEVAAH 1784 NEDAAHG+ NEVAAHGIAN EDAAQG+A E G+ANEDAV V E A H Sbjct: 589 NEDAAHGVANEVAAHGIANEVAVHCVAIEDAAQGVAKEVTAHGVANEDAVQGVVNEYALH 648 Query: 1785 G-VANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKE 1843 VANEDAA AIAKPDAA GIANEVAA IA ED A GI NEDAA G+ANEVAAHGISKE Sbjct: 649 SVVANEDAAQAIAKPDAAHGIANEVAAHSIANEDAAQGIANEDAAQGIANEVAAHGISKE 708 Query: 1844 DAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGI 1903 DAVQGIANEDAAQGIA ED QG+AHEDAVQGIANEDA HG+A E AA G+ Sbjct: 709 DAVQGIANEDAAQGIANED---------AAQGIAHEDAVQGIANEDAVHGVAKEVAAHGV 759 Query: 1904 ANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAA 1963 ANED Q +ANEDA QG++ E VQG+A++DA QGIA EDA GI NE AA GIANE AA Sbjct: 760 ANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAA 819 Query: 1964 HGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANE 2023 GIANEDAAQGIA+EDA QGIA+EDAV +A E A HGVANEDAAHAIAKPDAARGIANE Sbjct: 820 QGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANE 879 Query: 2024 VAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIA-ED 2082 VAAQGIATEDVADGIANEDAAHGVANE AA I+K DA GIAN ED A GIA ED Sbjct: 880 VAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIAN-----EDAAQGIAKED 934 Query: 2083 AVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVA 2142 +QG+ NE Q +A +DA GI EDAA G+ NE AAQG+ANEDAA +ANE AA G+A Sbjct: 935 PIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGIA 994 Query: 2143 NEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAH 2202 ED QGVANE QGVANEDAVQGVANEVEVQG+AH+DA+QGIANEDAA G+ANEVAAH Sbjct: 995 KEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAH 1054 Query: 2203 GVANEDAAQGVANEVAAQGVANEDAAQGVAN---------EVAVHGVANEDAARHMAKED 2253 G+ANEDAAQG+ANE AAQG+A+EDA QG+AN EVA HGVANEDAA +AK D Sbjct: 1055 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPD 1114 Query: 2254 AAQGIANEDAAHGIANEDAVHGIANEDAVYDIAND 2288 AA+GIANE AA GIA ED GIANEDA + +AN+ Sbjct: 1115 AARGIANEVAAQGIATEDVADGIANEDAAHGVANE 1149 Score = 1120 bits (2896), Expect = 0.0 Identities = 620/900 (68%), Positives = 673/900 (74%), Gaps = 102/900 (11%) Query: 51 EDTVHDIANEDA-------DAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHG 103 E H +ANEDA DAA GI NE A QG+A + A G+ANEDAAHGVANEVAAHG Sbjct: 545 EVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATQDVADGIANEDAAHGVANEVAAHG 604 Query: 104 VANE---------DAAQGVANEVAAQGVANEDAVQGV----------ANEDAVQGVANED 144 +ANE DAAQGVA EV A GVANEDAVQGV ANEDA Q +A D Sbjct: 605 IANEVAVHCVAIEDAAQGVAKEVTAHGVANEDAVQGVVNEYALHSVVANEDAAQAIAKPD 664 Query: 145 AVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKE------------------DAAQDIA 186 A GIANE AAH IANEDAAQGIANEDAAQ IA E DAAQ IA Sbjct: 665 AAHGIANEVAAHSIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIA 724 Query: 187 NEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQ 246 NEDAAQGI+ EDAVQGIANEDA G+AKE GVANEDPVQGVANEDAVQGVANEVEVQ Sbjct: 725 NEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQ 784 Query: 247 GVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 306 GVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED Sbjct: 785 GVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 844 Query: 307 AVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVA 366 AVH VAKEVAAHGVANEDAAHAIAKPDAA GIANEVA QGIATEDVADGIANEDAAHGVA Sbjct: 845 AVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVA 904 Query: 367 KEVTAHGVANEDAVQGVVNEDALHGV-----------------VANEDAAQAIAKPDAAH 409 EV AHG++ EDAVQG+ NEDA G+ VA+EDA Q IA DAAH Sbjct: 905 NEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAH 964 Query: 410 GIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHED 469 GIANE AA GIANEDAAQ IANE AA GI+KED VQG+ANED QG+A+EDA QG+A+E Sbjct: 965 GIANEDAAQGIANEDAAQDIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEV 1024 Query: 470 AVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIA 529 VQG+A+EDAV G+A E AAHG+AN+ AAH IA DAA+GIANE AAQGIA ED GIA Sbjct: 1025 EVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIA 1084 Query: 530 NEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAH 589 NEDAVHGVA EVAAHGVANEDAAHAIAKPDAA GIANEVA QGIATEDVADGIANEDAAH Sbjct: 1085 NEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAH 1144 Query: 590 GVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNE- 648 GVANE A +A DA G+ANE GVANE AAQGIA E A G+A EDAVQG+ NE Sbjct: 1145 GVANEDAAQAIAKPDAAHGIANE----GVANEVAAQGIATEDVADGIA-EDAVQGITNEE 1199 Query: 649 --------DALHGV--------VANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIA 692 DA HG+ V NE AAQ +A DAAHG+ANEVAAHG+ANEDAAQG+A Sbjct: 1200 AAQAIAKQDAAHGITNEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVA 1259 Query: 693 NEDAAQGIANEVAAHGISKEDAVQGIANE---------DAAQGIAHEDAVQGIANEDAVH 743 NE AAQG+ANE A HG++ EDAVQG+ANE DA QGIA+EDA QG+ANEDA Sbjct: 1260 NEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEDAAQ 1319 Query: 744 GVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEV 803 GVA EVAAHG VANED GVANEV QG+A+EDA QG+ANE A HG+ANE Sbjct: 1320 GVANEVAAHG---------VANEDAAHGVANEVAAQGVANEDAAQGVANEVAVHGVANED 1370 Query: 804 AAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVV 863 AA +A EDAAQ +ANEDAA G+ANEDAVHG+ANED+ G+A E + + N D VQG + Sbjct: 1371 AARHMAKEDAAQDIANEDAAHGIANEDAVHGIANEDSVYGIANEDAVYDIAN-DTVQGTL 1429 Score = 299 bits (766), Expect = 2e-80 Identities = 162/242 (66%), Positives = 180/242 (74%), Gaps = 25/242 (10%) Query: 51 EDTVHDIANEDA-------DAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHG 103 ED V I NE+A DAAHGITNEDA QGV NEVAAQGVANEDAAHGVANEVAAHG Sbjct: 1189 EDAVQGITNEEAAQAIAKQDAAHGITNEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHG 1248 Query: 104 VANEDAAQGVANEVAAQGVANEDAVQGVANEDAVQGV------------------ANEDA 145 VANEDAAQGVANEVAAQGVANEDAV GVANEDAVQGV ANEDA Sbjct: 1249 VANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDA 1308 Query: 146 VQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQGISKEDAVQGIAN 205 QG+ANEDAA G+ANE AA G+ANEDAA +A E AAQ +ANEDAAQG++ E AV G+AN Sbjct: 1309 AQGVANEDAAQGVANEVAAHGVANEDAAHGVANEVAAQGVANEDAAQGVANEVAVHGVAN 1368 Query: 206 EDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHG 265 EDAA+ +AKED Q +ANED G+ANEDAV G+ANE V G+A+EDAV IAN+ Sbjct: 1369 EDAARHMAKEDAAQDIANEDAAHGIANEDAVHGIANEDSVYGIANEDAVYDIANDTVQGT 1428 Query: 266 IT 267 +T Sbjct: 1429 LT 1430 Score = 191 bits (485), Expect = 7e-48 Identities = 123/245 (50%), Positives = 136/245 (55%), Gaps = 60/245 (24%) Query: 51 EDTVHDIANEDADAA-------HGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHG 103 ED VH +ANEDA GI ++DA+QG+ANE AAQGVANEDAA GVANEVAAHG Sbjct: 1270 EDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEDAAQGVANEVAAHG 1329 Query: 104 VANEDAAQGVANEVAAQGVANEDAVQGVANEDAVQGVANEDAV---------QGIANEDA 154 VANEDAA GVANEVAAQGVANEDA QGVANE AV GVANEDA Q IANEDA Sbjct: 1330 VANEDAAHGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQDIANEDA 1389 Query: 155 AHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQGIS------------------- 195 AHGIANEDA GIANED+ IA EDA DIAN D QG Sbjct: 1390 AHGIANEDAVHGIANEDSVYGIANEDAVYDIAN-DTVQGTLTRTLYRTSLMRTPYKASVM 1448 Query: 196 -------------KEDAVQGIANEDAAQGIAKEDPVQGV-----------ANEDPVQGVA 231 K + + + K P++ + AN D V +A Sbjct: 1449 RTLYTTSLTRTPYKPSLTRTLYTTSLMRAPYKTSPMRALYTTLLMIPTRHANADTVHDIA 1508 Query: 232 NEDAV 236 NED V Sbjct: 1509 NEDTV 1513 >gi|239752511 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 609 Score = 694 bits (1792), Expect = 0.0 Identities = 383/616 (62%), Positives = 425/616 (68%), Gaps = 30/616 (4%) Query: 1212 EDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQG 1271 ED H IA DA IA E A IA ED GIA EDAA G+ANE A H I+ EDA Sbjct: 13 EDTVHDIANEDAVYDIATEDAIYDIANEDAVQGIAKEDAAQGIANEEAVHDIANEDAAHV 72 Query: 1272 IANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDA 1331 IANEDAAQ IA EDAV IANEDA QGI ED +ANED GVANEV A Sbjct: 73 IANEDAAQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEV---------A 123 Query: 1332 VQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAK 1391 QG+ANEDA H IANEDAAQGIANEDAA IANEDAAQ I+ EDA Q IANEDAAQGI+K Sbjct: 124 AQGVANEDAVHCIANEDAAQGIANEDAAHGIANEDAAQDIANEDAAQDIANEDAAQGISK 183 Query: 1392 EDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQG 1451 ED VQG+ANEDA QG+A E VQGVA+ED VQG+ANEDA GIA E D QG Sbjct: 184 EDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGIAKE---------DPVQG 234 Query: 1452 IANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVA 1511 +ANED QG+A+EDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVA Sbjct: 235 VANEDPVQGVANEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVA 294 Query: 1512 TQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVAN 1571 QGIATEDVADGIANEDAAHGVANEVAAQG+ANE AV GVA EDA QGV KEVTAHGVAN Sbjct: 295 AQGIATEDVADGIANEDAAHGVANEVAAQGVANEDAVEGVANEDAAQGVAKEVTAHGVAN 354 Query: 1572 EDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQ 1631 EDAVQGVVNEDALH VVANEDAAQAIAKPDAAHGIANEV A IAN+ A IA +D Sbjct: 355 EDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVTAQGIANEVAIHSIAIEDTTP 414 Query: 1632 GIA-----------NEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIAN 1680 A ++ + + + ++ + + + Sbjct: 415 SRAWLTRSLPRASLPRMSPTASLRTPPMASLTRRPPRPSLSRMPPTASLTRTPSRASLTR 474 Query: 1681 EDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHG 1740 + + + P + +GVANEVEVQG+AH+DA+QGIANEDAAHG Sbjct: 475 SPPRASLTRTPPTASLTRSPPTASLTRTPP-RGVANEVEVQGIAHKDAIQGIANEDAAHG 533 Query: 1741 ITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDA 1800 I NEVAAHGIANEDAAQGIA+EDA QGIANE A H ++KE G+ANEDAA IAK + Sbjct: 534 IANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDTVQGIANEDAAQGIAKENP 593 Query: 1801 ARGIANEVAAQGIATE 1816 +G+ANE QG+A E Sbjct: 594 VQGVANEDPVQGVANE 609 Score = 681 bits (1758), Expect = 0.0 Identities = 380/617 (61%), Positives = 421/617 (68%), Gaps = 39/617 (6%) Query: 278 EDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHG 337 ED IANEDA IA EDA+ IANEDAV G+AKE AA G+ANE+A H IA DAAH Sbjct: 13 EDTVHDIANEDAVYDIATEDAIYDIANEDAVQGIAKEDAAQGIANEEAVHDIANEDAAHV 72 Query: 338 IANEVATQGIATEDVADGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANED 397 IANE A Q IA ED IANEDA G+ E AH +ANEDA GV NE A GV ANED Sbjct: 73 IANEDAAQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVAAQGV-ANED 131 Query: 398 AAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIA 457 A IA DAA GIANE AAHGIANEDAAQ IANE AA I+ EDA QGI+ EDA QGIA Sbjct: 132 AVHCIANEDAAQGIANEDAAHGIANEDAAQDIANEDAAQDIANEDAAQGISKEDAVQGIA 191 Query: 458 HEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQ 517 +EDAAQGIA ED VQG+ANED V GVA N+DA IAK D +G+ANE Q Sbjct: 192 NEDAAQGIAKEDPVQGVANEDPVQGVA---------NEDAVQGIAKEDPVQGVANEDPVQ 242 Query: 518 GIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATED 577 G+A ED GIANEDAVHGVA EVAAHGVANEDAAHAIAKPDAA GIANEVA QGIATED Sbjct: 243 GVANEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATED 302 Query: 578 VADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVA 637 VADGIANEDAAHGVANEVA QGVANEDAV GVANEDAAQG+AKEVTAHGVA Sbjct: 303 VADGIANEDAAHGVANEVAA---------QGVANEDAVEGVANEDAAQGVAKEVTAHGVA 353 Query: 638 NEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAA 697 NEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEV A GIANE A IA ED Sbjct: 354 NEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVTAQGIANEVAIHSIAIEDTT 413 Query: 698 QGIA-----------NEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVA 746 A ++ + + + ++ + + + Sbjct: 414 PSRAWLTRSLPRASLPRMSPTASLRTPPMASLTRRPPRPSLSRMPPTASLTRTPSRASLT 473 Query: 747 KEVAAHGVANEDPVQGVANEDVV--------QGVANEVEVQGIAHEDAVQGIANEDAAHG 798 + + P + +GVANEVEVQGIAH+DA+QGIANEDAAHG Sbjct: 474 RSPPRASLTRTPPTASLTRSPPTASLTRTPPRGVANEVEVQGIAHKDAIQGIANEDAAHG 533 Query: 799 IANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDA 858 IANEVAAHG+ANEDAAQG+ANEDAAQG+ANE A HG++ ED QG+A E A G+ E+ Sbjct: 534 IANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDTVQGIANEDAAQGIAKENP 593 Query: 859 VQGVVNEEALHGVVANE 875 VQGV NE+ + G VANE Sbjct: 594 VQGVANEDPVQG-VANE 609 Score = 647 bits (1668), Expect = 0.0 Identities = 361/632 (57%), Positives = 414/632 (65%), Gaps = 63/632 (9%) Query: 933 QDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQG 992 +D H I NEDA +A EDA + +ANEDA QG+A E AAQG+ANE+AVH +ANEDA Sbjct: 13 EDTVHDIANEDAVYDIATEDAIYDIANEDAVQGIAKEDAAQGIANEEAVHDIANEDAAHV 72 Query: 993 VANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVA 1052 +ANE DA Q IANEDA H IANE A GI NEDAA IANEDAA G+ANEVA Sbjct: 73 IANE---------DAAQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVA 123 Query: 1053 AHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVAN 1112 A G++ EDAV IANEDAAQGIANEDAA GIA+EDA Q IANEDA +A E AA G++ Sbjct: 124 AQGVANEDAVHCIANEDAAQGIANEDAAHGIANEDAAQDIANEDAAQDIANEDAAQGISK 183 Query: 1113 EDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQG 1172 ED VQG+ANEDA QG+A E VQGVA+ED VQG+ANEDA GIA E D QG Sbjct: 184 EDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGIAKE---------DPVQG 234 Query: 1173 IANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVA 1232 +ANED QG+A+EDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVA Sbjct: 235 VANEDPVQGVANEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVA 294 Query: 1233 AQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIAN 1292 AQGIATEDVADGIANEDAAHGVANEVAA G++ EDAV+G+ANEDAAQG+AKE G+AN Sbjct: 295 AQGIATEDVADGIANEDAAHGVANEVAAQGVANEDAVEGVANEDAAQGVAKEVTAHGVAN 354 Query: 1293 EDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQG 1352 EDA VQGV NED + GV VA+EDA Q IA DAAHGIANE AQG Sbjct: 355 EDA---------VQGVVNEDALHGV--------VANEDAAQAIAKPDAAHGIANEVTAQG 397 Query: 1353 IANEDAAQDIANEDAAQGIS--------------------KEDAVQGIANEDAAQGIAKE 1392 IANE A IA ED + + + + +++ Sbjct: 398 IANEVAIHSIAIEDTTPSRAWLTRSLPRASLPRMSPTASLRTPPMASLTRRPPRPSLSRM 457 Query: 1393 DPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAA--------HGIANEVAAHGIA 1444 P + + + + + G+ANEV GIA Sbjct: 458 PPTASLTRTPSRASLTRSPPRASLTRTPPTASLTRSPPTASLTRTPPRGVANEVEVQGIA 517 Query: 1445 NEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAR 1504 ++DA QGIANEDAA GIA+E A GIANEDA G+A E AA G+ANE AAH I+K D + Sbjct: 518 HKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDTVQ 577 Query: 1505 GIANEVATQGIATEDVADGIANEDAAHGVANE 1536 GIANE A QGIA E+ G+ANED GVANE Sbjct: 578 GIANEDAAQGIAKENPVQGVANEDPVQGVANE 609 Score = 642 bits (1657), Expect = 0.0 Identities = 360/621 (57%), Positives = 408/621 (65%), Gaps = 59/621 (9%) Query: 48 TPYEDTVHDIANEDADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANE 107 +PYEDTVHDIANEDA + I EDA+ +ANE A QG+A EDAA G+ANE A H +ANE Sbjct: 10 SPYEDTVHDIANEDA--VYDIATEDAIYDIANEDAVQGIAKEDAAQGIANEEAVHDIANE 67 Query: 108 DAAQGVANEVAAQGVANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGI 167 DAA +ANE AAQ +ANEDAV +ANEDA QG+ NEDA IANEDAAHG+ANE AAQG+ Sbjct: 68 DAAHVIANEDAAQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVAAQGV 127 Query: 168 ANEDAAQDIAKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPV 227 ANEDA IA EDAAQ IANEDAA GI+ EDA Q IANEDAAQ IA ED QG++ ED V Sbjct: 128 ANEDAVHCIANEDAAQGIANEDAAHGIANEDAAQDIANEDAAQDIANEDAAQGISKEDAV 187 Query: 228 QGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANE 287 QG+ANEDA QG+A E VQGVA+ED VQG+ANEDA GI A ED QG+ANE Sbjct: 188 QGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGI---------AKEDPVQGVANE 238 Query: 288 DAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGI 347 D QG+A+EDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAA GIANEVA QGI Sbjct: 239 DPVQGVANEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGI 298 Query: 348 ATEDVADGIANEDAAHGVA---------------------------KEVTAHGVANEDAV 380 ATEDVADGIANEDAAHGVA KEVTAHGVANEDAV Sbjct: 299 ATEDVADGIANEDAAHGVANEVAAQGVANEDAVEGVANEDAAQGVAKEVTAHGVANEDAV 358 Query: 381 QGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISK 440 QGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEV AQGIANEVA H I+ Sbjct: 359 QGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEV---------TAQGIANEVAIHSIAI 409 Query: 441 EDAVQGIA-----------NEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAA 489 ED A + + ++ + + + Sbjct: 410 EDTTPSRAWLTRSLPRASLPRMSPTASLRTPPMASLTRRPPRPSLSRMPPTASLTRTPSR 469 Query: 490 HGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANE 549 + ++ + + + T G+ANE V G+A++ A G+ANE Sbjct: 470 ASLTRSPPRASLTRTPPTASLTRSPPTASL-TRTPPRGVANEVEVQGIAHKDAIQGIANE 528 Query: 550 DAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGV 609 DAAH IA AAHGIANE A QGIA ED A GIANE AAHG++ E V G+A EDA QG+ Sbjct: 529 DAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDTVQGIANEDAAQGI 588 Query: 610 ANEDAVHGVANEDAAQGIAKE 630 A E+ V GVANED QG+A E Sbjct: 589 AKENPVQGVANEDPVQGVANE 609 Score = 634 bits (1636), Expect = 0.0 Identities = 358/607 (58%), Positives = 403/607 (66%), Gaps = 61/607 (10%) Query: 522 EDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADG 581 ED IANEDAV+ +A E A + +ANEDA IAK DAA GIANE A IA ED A Sbjct: 13 EDTVHDIANEDAVYDIATEDAIYDIANEDAVQGIAKEDAAQGIANEEAVHDIANEDAAHV 72 Query: 582 IANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDA 641 IANEDAA +ANE AVH +A EDA QG+ NEDA H +ANEDAA G+A EV A GVANEDA Sbjct: 73 IANEDAAQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVAAQGVANEDA 132 Query: 642 VQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIA 701 V + NEDA G+ ANEDAA IA DAA IANE AA IANEDAAQGI+ EDA QGIA Sbjct: 133 VHCIANEDAAQGI-ANEDAAHGIANEDAAQDIANEDAAQDIANEDAAQGISKEDAVQGIA 191 Query: 702 NEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQ 761 NE AA GI+KED VQG+ANED QG+A+EDAVQGIA ED V GVA E GVANED VQ Sbjct: 192 NEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGIAKEDPVQGVANEDPVQGVANEDAVQ 251 Query: 762 GVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVA---------NED 812 G+ANED V GVA EV G+A+EDA IA DAA GIANEVAA G+A NED Sbjct: 252 GIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANED 311 Query: 813 AAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVV 872 AA GVANE AAQGVANEDAV GVANEDAAQGVAKEVTAHGV NEDAVQGVVNE+ALHGVV Sbjct: 312 AAHGVANEVAAQGVANEDAVEGVANEDAAQGVAKEVTAHGVANEDAVQGVVNEDALHGVV 371 Query: 873 ANEDAAQAIAKPDAAHGIANE----GVANEVAAQGIATEDVADGIA-------------- 914 ANEDAAQAIAKPDAAHGIANE G+ANEVA IA ED A Sbjct: 372 ANEDAAQAIAKPDAAHGIANEVTAQGIANEVAIHSIAIEDTTPSRAWLTRSLPRASLPRM 431 Query: 915 -------KDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAA---- 963 +T+ ++++ S+T + + + Sbjct: 432 SPTASLRTPPMASLTRRPPRPSLSRMPPTASLTRTPSRASLTRSPPRASLTRTPPTASLT 491 Query: 964 -------------QGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQG 1010 +GVANEV QG+A++DA+ G+ANEDA G+ANEV GIA++DA QG Sbjct: 492 RSPPTASLTRTPPRGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQG 551 Query: 1011 IANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDA 1070 IANEDAA GIANEVAAHGI+ ED QGIANEDAAQGIA KE+ VQG+ANED Sbjct: 552 IANEDAAQGIANEVAAHGISKEDTVQGIANEDAAQGIA---------KENPVQGVANEDP 602 Query: 1071 AQGIANE 1077 QG+ANE Sbjct: 603 VQGVANE 609 Score = 632 bits (1630), Expect = e-180 Identities = 342/624 (54%), Positives = 404/624 (64%), Gaps = 47/624 (7%) Query: 915 KDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQG 974 +D H I E+A IA +DA + I NEDA QG+A EDAA G+ANE+A +ANE AA Sbjct: 13 EDTVHDIANEDAVYDIATEDAIYDIANEDAVQGIAKEDAAQGIANEEAVHDIANEDAAHV 72 Query: 975 VANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDA 1034 +ANEDA +ANEDAV +ANE QGI ++DA IANEDAAHG+ANEVAA G+ANEDA Sbjct: 73 IANEDAAQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVAAQGVANEDA 132 Query: 1035 AQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIAN 1094 IANEDAAQGIANE AAHGI+ EDA Q IANEDAAQ IANEDAAQGI+ EDAVQGIAN Sbjct: 133 VHCIANEDAAQGIANEDAAHGIANEDAAQDIANEDAAQDIANEDAAQGISKEDAVQGIAN 192 Query: 1095 EDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHG 1154 EDA G+AKE DPVQGVANED VQGVANE VQG+A ED VQG+ANED G Sbjct: 193 EDAAQGIAKE---------DPVQGVANEDPVQGVANEDAVQGIAKEDPVQGVANEDPVQG 243 Query: 1155 IANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDA 1214 +ANE A GIANEDA G+A E AA G+A+EDA IA DA G+A EVAA G+A ED Sbjct: 244 VANEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDV 303 Query: 1215 AHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIAN 1274 A IA DAA G+ANEVAAQG+A ED +G+ANEDAA GVA EV AHG++ EDAVQG+ N Sbjct: 304 ADGIANEDAAHGVANEVAAQGVANEDAVEGVANEDAAQGVAKEVTAHGVANEDAVQGVVN 363 Query: 1275 EDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQG 1334 EDA G+ +ANEDAAQ IAK D G+ANE QG+ANEV + +A ED Sbjct: 364 EDALHGV--------VANEDAAQAIAKPDAAHGIANEVTAQGIANEVAIHSIAIEDTTPS 415 Query: 1335 IA--------------------NEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKE 1374 A + ++ + + +++ Sbjct: 416 RAWLTRSLPRASLPRMSPTASLRTPPMASLTRRPPRPSLSRMPPTASLTRTPSRASLTRS 475 Query: 1375 DAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGI 1434 + + + P + +GVANEVEVQG+AH+DA+QGIANEDAAHGI Sbjct: 476 PPRASLTRTPPTASLTRSPPTASLTRTPP-RGVANEVEVQGIAHKDAIQGIANEDAAHGI 534 Query: 1435 ANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAA 1494 ANEVAAHGIANEDAAQGIANEDAA QGIANE A HG++KE G+ANEDAA Sbjct: 535 ANEVAAHGIANEDAAQGIANEDAA---------QGIANEVAAHGISKEDTVQGIANEDAA 585 Query: 1495 HAIAKPDAARGIANEVATQGIATE 1518 IAK + +G+ANE QG+A E Sbjct: 586 QGIAKENPVQGVANEDPVQGVANE 609 Score = 627 bits (1618), Expect = e-179 Identities = 345/608 (56%), Positives = 405/608 (66%), Gaps = 38/608 (6%) Query: 1636 EVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHG 1695 E H I+ EDAV IA EDA IANEDA QGIA EDA QGIANE+AVH +A E AAH Sbjct: 13 EDTVHDIANEDAVYDIATEDAIYDIANEDAVQGIAKEDAAQGIANEEAVHDIANEDAAHV 72 Query: 1696 VANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDA 1755 +ANED Q +ANEDAV +ANE QG+ +EDA IANEDAAHG+ NEVAA G+ANEDA Sbjct: 73 IANEDAAQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVAAQGVANEDA 132 Query: 1756 AQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIAT 1815 IA+EDA QGIANEDA AHG+ANEDAA IA DAA+ IANE AAQGI+ Sbjct: 133 VHCIANEDAAQGIANEDA---------AHGIANEDAAQDIANEDAAQDIANEDAAQGISK 183 Query: 1816 EDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQG 1875 ED GI NEDAA G+A E G++ ED VQG+ANEDA QGIAKEDP+QGVANE VQG Sbjct: 184 EDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGIAKEDPVQGVANEDPVQG 243 Query: 1876 VAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDA 1935 VA+EDAVQGIANEDA HG+A E AA G+ANEDAA IA DAA+GI+ E A QGIA +D Sbjct: 244 VANEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDV 303 Query: 1936 AQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIAN 1995 A GIA EDA G+ANE AAQG+ANE A G+ANEDAAQG+A E A G+A+EDAVQG+ N Sbjct: 304 ADGIANEDAAHGVANEVAAQGVANEDAVEGVANEDAAQGVAKEVTAHGVANEDAVQGVVN 363 Query: 1996 EDAVHG-VANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQ 2054 EDA+HG VANEDAA AIAKPDAA GIANEV AQGIA E IA ED A + Sbjct: 364 EDALHGVVANEDAAQAIAKPDAAHGIANEVTAQGIANEVAIHSIAIEDTTPSRA--WLTR 421 Query: 2055 AIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITK------- 2107 ++ + + T +A ++ ++ + + +T+ Sbjct: 422 SLPRASLPRMSPTASLRTPPMASLTRRPPRPSLSRMPPTASLTRTPSRASLTRSPPRASL 481 Query: 2108 -------------------EDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQ 2148 +GV NEV QG+A++DA G+ANE AAHG+ANE AA Sbjct: 482 TRTPPTASLTRSPPTASLTRTPPRGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAH 541 Query: 2149 GVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANED 2208 G+ANE AAQG+ANEDA QG+ANEV GI+ +D +QGIANEDAAQG+A E GVANED Sbjct: 542 GIANEDAAQGIANEDAAQGIANEVAAHGISKEDTVQGIANEDAAQGIAKENPVQGVANED 601 Query: 2209 AAQGVANE 2216 QGVANE Sbjct: 602 PVQGVANE 609 Score = 619 bits (1595), Expect = e-176 Identities = 347/614 (56%), Positives = 405/614 (65%), Gaps = 31/614 (5%) Query: 1527 EDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHS 1586 ED H +ANE A IA E A++ +A EDAVQG+ KE A G+ANE+AV + NEDA H Sbjct: 13 EDTVHDIANEDAVYDIATEDAIYDIANEDAVQGIAKEDAAQGIANEEAVHDIANEDAAH- 71 Query: 1587 VVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKED 1646 V+ANEDAAQ+IA DA H IANE A I N+DAA IAN+DAA G+ANEVAA G++ ED Sbjct: 72 VIANEDAAQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVAAQGVANED 131 Query: 1647 AVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVA 1706 AV IANEDAAQGIANEDAA GIA+EDA Q IANEDA +A E AA G++ ED VQG+A Sbjct: 132 AVHCIANEDAAQGIANEDAAHGIANEDAAQDIANEDAAQDIANEDAAQGISKEDAVQGIA 191 Query: 1707 NEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQ 1766 NEDA QG+A E VQGVA+ED VQG+ANEDA GI E G+ANED QG+A+EDAVQ Sbjct: 192 NEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGIAKEDPVQGVANEDPVQGVANEDAVQ 251 Query: 1767 GIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNED 1826 GIANEDAVH VAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGI NED Sbjct: 252 GIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANED 311 Query: 1827 AAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIA 1886 AAHGVANEVAA G++ EDAV+G+ANEDAAQG+AK EV GVA+EDAVQG+ Sbjct: 312 AAHGVANEVAAQGVANEDAVEGVANEDAAQGVAK---------EVTAHGVANEDAVQGVV 362 Query: 1887 NEDAAHG-IANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAA--------- 1936 NEDA HG +ANEDAAQ IA DAA IANE AQGI+ E A+ IA +D Sbjct: 363 NEDALHGVVANEDAAQAIAKPDAAHGIANEVTAQGIANEVAIHSIAIEDTTPSRAWLTRS 422 Query: 1937 ---QGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGI 1993 + + + A + ++ + + + + Sbjct: 423 LPRASLPRMSPTASLRTPPMA-SLTRRPPRPSLSRMPPTASLTRTPSRASLTRSPPRASL 481 Query: 1994 ANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAA 2053 + ++ + RG+ANEV QGIA +D GIANEDAAHG+ANE AA Sbjct: 482 TRTPPTASLTRSPPTASLTR-TPPRGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAA 540 Query: 2054 QAIAKPDAAHGIANEGIATEDVADGIA-EDAVQGITNEEAAQAIAKQDAAHGITKEDAAQ 2112 IA DAA GIAN ED A GIA E A GI+ E+ Q IA +DAA GI KE+ Q Sbjct: 541 HGIANEDAAQGIAN-----EDAAQGIANEVAAHGISKEDTVQGIANEDAAQGIAKENPVQ 595 Query: 2113 GVTNEVAAQGVANE 2126 GV NE QGVANE Sbjct: 596 GVANEDPVQGVANE 609 Score = 610 bits (1573), Expect = e-174 Identities = 344/615 (55%), Positives = 387/615 (62%), Gaps = 46/615 (7%) Query: 1203 EVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHG 1262 E H +ANEDA + IA DA IANE A QGIA ED A GIANE+A H +ANE AAH Sbjct: 13 EDTVHDIANEDAVYDIATEDAIYDIANEDAVQGIAKEDAAQGIANEEAVHDIANEDAAHV 72 Query: 1263 ISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVE 1322 I+ EDA Q IANEDA IA EDA QGI NEDAA IA ED GVANE QGVANE Sbjct: 73 IANEDAAQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVAAQGVANEDA 132 Query: 1323 VQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIAN 1382 V +A+EDA QGIANEDAAHGIANEDAAQ IANEDAAQDIANEDAAQGISKEDAVQGIAN Sbjct: 133 VHCIANEDAAQGIANEDAAHGIANEDAAQDIANEDAAQDIANEDAAQGISKEDAVQGIAN 192 Query: 1383 EDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHG 1442 EDAAQGIAKEDPVQGVANED VQGVANE VQG+A ED VQG+ANED G+ANE A G Sbjct: 193 EDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGIAKEDPVQGVANEDPVQGVANEDAVQG 252 Query: 1443 IANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDA 1502 IANEDA G+A E AA G+A+EDA IA DA G+A EVAA G+A ED A IA DA Sbjct: 253 IANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDA 312 Query: 1503 ARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVK 1562 A G+ANEVA QG+A ED +G+ANEDAA GVA EV A G+ANE AV GV EDA+ GV Sbjct: 313 AHGVANEVAAQGVANEDAVEGVANEDAAQGVAKEVTAHGVANEDAVQGVVNEDALHGV-- 370 Query: 1563 EVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQ 1622 VANEDA Q + DA H +ANE AQ GIANEVA HSIA +D Sbjct: 371 ------VANEDAAQAIAKPDAAHG-IANEVTAQ---------GIANEVAIHSIAIEDTTP 414 Query: 1623 GIA--------------------NQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAN 1662 A + +S+ + + + Sbjct: 415 SRAWLTRSLPRASLPRMSPTASLRTPPMASLTRRPPRPSLSRMPPTASLTRTPSRASLTR 474 Query: 1663 EDAAQGIAHEDAVQGIANEDAV--------HGVAKEVAAHGVANEDPVQGVANEDAVQGV 1714 + + GVA EV G+A++D +QG+ANEDA G+ Sbjct: 475 SPPRASLTRTPPTASLTRSPPTASLTRTPPRGVANEVEVQGIAHKDAIQGIANEDAAHGI 534 Query: 1715 ANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAV 1774 ANEV G+A+EDA QGIANEDAA GI NEVAAHGI+ ED QGIA+EDA QGIA E+ V Sbjct: 535 ANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDTVQGIANEDAAQGIAKENPV 594 Query: 1775 HSVAKEVAAHGVANE 1789 VA E GVANE Sbjct: 595 QGVANEDPVQGVANE 609 Score = 607 bits (1565), Expect = e-173 Identities = 339/617 (54%), Positives = 394/617 (63%), Gaps = 48/617 (7%) Query: 1328 HEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQ 1387 +ED V IANEDA + IA EDA IANEDA Q IA EDAAQGI+ E+AV IANEDAA Sbjct: 12 YEDTVHDIANEDAVYDIATEDAIYDIANEDAVQGIAKEDAAQGIANEEAVHDIANEDAAH 71 Query: 1388 GIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANED 1447 IA ED Q +ANEDAV +ANE QG+ +EDA IANEDAAHG+ANEVAA G+ANED Sbjct: 72 VIANEDAAQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVAAQGVANED 131 Query: 1448 AAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIA 1507 A IANEDAAQGIA+EDA GIANEDA +A E AA +ANEDAA I+K DA +GIA Sbjct: 132 AVHCIANEDAAQGIANEDAAHGIANEDAAQDIANEDAAQDIANEDAAQGISKEDAVQGIA 191 Query: 1508 NEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAH 1567 NE A QGIA ED G+ANED GVANE A QGIA E V GVA ED VQGV E Sbjct: 192 NEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGIAKEDPVQGVANEDPVQGVANEDAVQ 251 Query: 1568 GVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQ 1627 G+ANEDAV GV E A H VANEDAA AIAKPDAA GIANEVAA IA +D A GIAN+ Sbjct: 252 GIANEDAVHGVAKEVAAHG-VANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANE 310 Query: 1628 DAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1687 DAA G+ANEVAA G++ EDAV+G+ANEDAAQG+A E A G+A+EDAVQG+ NEDA+HGV Sbjct: 311 DAAHGVANEVAAQGVANEDAVEGVANEDAAQGVAKEVTAHGVANEDAVQGVVNEDALHGV 370 Query: 1688 AKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAA--------- 1738 VANED Q +A DA G+ANEV QG+A+E A+ IA ED Sbjct: 371 --------VANEDAAQAIAKPDAAHGIANEVTAQGIANEVAIHSIAIEDTTPSRAWLTRS 422 Query: 1739 --------------------HGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVA 1778 +T ++ + + + S+ Sbjct: 423 LPRASLPRMSPTASLRTPPMASLTRRPPRPSLSRMPPTASLTRTPSRASLTRSPPRASLT 482 Query: 1779 KEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAH 1838 + + ++ + RG+ANEV QGIA +D GI NEDAAHG+ANEVAAH Sbjct: 483 RTPPTASLTRSPPTASLTR-TPPRGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAH 541 Query: 1839 GISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANED 1898 GI+ EDA QGIANEDAAQGI ANEV G++ ED VQGIANEDAA GIA E+ Sbjct: 542 GIANEDAAQGIANEDAAQGI---------ANEVAAHGISKEDTVQGIANEDAAQGIAKEN 592 Query: 1899 AAQGIANEDAAQDIANE 1915 QG+ANED Q +ANE Sbjct: 593 PVQGVANEDPVQGVANE 609 Score = 598 bits (1541), Expect = e-170 Identities = 323/598 (54%), Positives = 382/598 (63%), Gaps = 24/598 (4%) Query: 729 HEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQ 788 +ED V IANEDAV+ +A E A + +ANED VQG+A ED QG+ANE V IA+EDA Sbjct: 12 YEDTVHDIANEDAVYDIATEDAIYDIANEDAVQGIAKEDAAQGIANEEAVHDIANEDAAH 71 Query: 789 GIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEV 848 IANEDAA IANE A H +ANEDA QG+ NEDAA +ANEDA HGVANE AAQGVA E Sbjct: 72 VIANEDAAQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVAAQGVANED 131 Query: 849 TAHGVTNEDAVQGVVNEEALHGV--------VANEDAAQAIAKPDAAHGIANE----GVA 896 H + NEDA QG+ NE+A HG+ +ANEDAAQ IA DAA GI+ E G+A Sbjct: 132 AVHCIANEDAAQGIANEDAAHGIANEDAAQDIANEDAAQDIANEDAAQGISKEDAVQGIA 191 Query: 897 NEVAAQGIATEDVADGIA-KDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAH 955 NE AAQGIA ED G+A +D G+ E+A Q IAK+D + NED QGVANEDA Sbjct: 192 NEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGIAKEDPVQGVANEDPVQGVANEDAVQ 251 Query: 956 GVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANED 1015 G+ANEDA GVA EVAA GVANEDA H +A DA +G+ANEV QGIA +D GIANED Sbjct: 252 GIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANED 311 Query: 1016 AAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG-I 1074 AAHG+ANEVAA G+ANEDA +G+ANEDAAQG+A EV AHG++ EDAVQG+ NEDA G + Sbjct: 312 AAHGVANEVAAQGVANEDAVEGVANEDAAQGVAKEVTAHGVANEDAVQGVVNEDALHGVV 371 Query: 1075 ANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANED--PVQGVANEDAVQGVANEV 1132 ANEDAAQ IA DA GIANE G+A EVA H +A ED P + + + Sbjct: 372 ANEDAAQAIAKPDAAHGIANEVTAQGIANEVAIHSIAIEDTTPSRAWLTRSLPRASLPRM 431 Query: 1133 EVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIA 1192 + + ++ + + + + + Sbjct: 432 SPTASLRTPPMASLTRRPPRPSLSRMPPTASLTRTPSRASLTRSPPRASLTRTPPTASLT 491 Query: 1193 NEDAV--------HGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADG 1244 GVA EV G+A++DA IA DAA GIANEVAA GIA ED A G Sbjct: 492 RSPPTASLTRTPPRGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQG 551 Query: 1245 IANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKE 1302 IANEDAA G+ANEVAAHGISKED VQGIANEDAAQGIAKE+ VQG+ANED QG+A E Sbjct: 552 IANEDAAQGIANEVAAHGISKEDTVQGIANEDAAQGIAKENPVQGVANEDPVQGVANE 609 Score = 594 bits (1532), Expect = e-169 Identities = 330/616 (53%), Positives = 387/616 (62%), Gaps = 28/616 (4%) Query: 1004 HKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQ 1063 ++D + IANEDA + IA E A + IANEDA QGIA EDAAQGIANE A H I+ EDA Sbjct: 12 YEDTVHDIANEDAVYDIATEDAIYDIANEDAVQGIAKEDAAQGIANEEAVHDIANEDAAH 71 Query: 1064 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANED 1123 IANEDAAQ IANEDA IA+EDA QGI NEDA H +A E AAHGVANE QGVANED Sbjct: 72 VIANEDAAQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVAAQGVANED 131 Query: 1124 AVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIA 1183 AV +ANE QG+A+EDA GIANEDAA IANE AA IANEDAAQGI+ EDA QGIA Sbjct: 132 AVHCIANEDAAQGIANEDAAHGIANEDAAQDIANEDAAQDIANEDAAQGISKEDAVQGIA 191 Query: 1184 HEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVAD 1243 +EDA QGIA ED V GVA E GVANEDA IAK D +G+ANE QG+A ED Sbjct: 192 NEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGIAKEDPVQGVANEDPVQGVANEDAVQ 251 Query: 1244 GIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKED 1303 GIANEDA HGVA EVAAH G+ANEDAA IAK DA +GIANE AAQGIA ED Sbjct: 252 GIANEDAVHGVAKEVAAH---------GVANEDAAHAIAKPDAARGIANEVAAQGIATED 302 Query: 1304 PVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIA 1363 G+ANED GVANEV QGVA+EDAV+G+ANEDAA G+A E A G+ANEDA Q + Sbjct: 303 VADGIANEDAAHGVANEVAAQGVANEDAVEGVANEDAAQGVAKEVTAHGVANEDAVQGVV 362 Query: 1364 NEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQ 1423 NEDA G+ +ANEDAAQ IAK D G+ANE QG+ANEV + +A ED Sbjct: 363 NEDALHGV--------VANEDAAQAIAKPDAAHGIANEVTAQGIANEVAIHSIAIEDTTP 414 Query: 1424 GIA--NEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAK 1481 A ++ + ++ + + + + Sbjct: 415 SRAWLTRSLPRASLPRMSPTASLRTPPMASLTRRPPRPSLSRMPPTASLTRTPSRASLTR 474 Query: 1482 EVAAHGVANEDAAHAIAK--PDAA------RGIANEVATQGIATEDVADGIANEDAAHGV 1533 + ++ + P A+ RG+ANEV QGIA +D GIANEDAAHG+ Sbjct: 475 SPPRASLTRTPPTASLTRSPPTASLTRTPPRGVANEVEVQGIAHKDAIQGIANEDAAHGI 534 Query: 1534 ANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDA 1593 ANEVAA GIANE A G+A EDA QG+ EV AHG++ ED VQG+ NEDA +A E+ Sbjct: 535 ANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDTVQGIANEDAAQG-IAKENP 593 Query: 1594 AQAIAKPDAAHGIANE 1609 Q +A D G+ANE Sbjct: 594 VQGVANEDPVQGVANE 609 Score = 592 bits (1525), Expect = e-168 Identities = 330/592 (55%), Positives = 382/592 (64%), Gaps = 50/592 (8%) Query: 895 VANEVAAQGIATEDVADGIA-KDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDA 953 +ANE A IATED IA +DA GI KE+AAQ IA ++A H I NEDAA +ANEDA Sbjct: 19 IANEDAVYDIATEDAIYDIANEDAVQGIAKEDAAQGIANEEAVHDIANEDAAHVIANEDA 78 Query: 954 AHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIAN 1013 A +ANEDA +ANE A QG+ NEDA H +ANEDA GVANEV QG+A++DA+ IAN Sbjct: 79 AQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVAAQGVANEDAVHCIAN 138 Query: 1014 EDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG 1073 EDAA GIANE AAHGIANEDAAQ IANEDAAQ IANE AA GISKEDAVQGIANEDAAQG Sbjct: 139 EDAAQGIANEDAAHGIANEDAAQDIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQG 198 Query: 1074 IANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVE 1133 IA ED QG+A+ED VQG+ANEDAV G+AKE GVANEDPVQGVANEDAVQG+ANE Sbjct: 199 IAKEDPVQGVANEDPVQGVANEDAVQGIAKEDPVQGVANEDPVQGVANEDAVQGIANEDA 258 Query: 1134 VQGVAHEDAVQGIANEDAAH---------GIANEVAAHGIANEDAAQGIANEDAAQGIAH 1184 V GVA E A G+ANEDAAH GIANEVAA GIA ED A GIANEDAA G+A+ Sbjct: 259 VHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVAN 318 Query: 1185 EDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGI-ATEDVAD 1243 E A QG+ANEDAV GVA E AA GVA E AH +A DA +G+ NE A G+ A ED A Sbjct: 319 EVAAQGVANEDAVEGVANEDAAQGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQ 378 Query: 1244 GIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQG----------------------- 1280 IA DAAHG+ANEV A GI+ E A+ IA ED Sbjct: 379 AIAKPDAAHGIANEVTAQGIANEVAIHSIAIEDTTPSRAWLTRSLPRASLPRMSPTASLR 438 Query: 1281 ---------------IAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQG 1325 +++ + + + + P + P + Sbjct: 439 TPPMASLTRRPPRPSLSRMPPTASLTRTPSRASLTRSPPRASLTRTPPTASLTRSPPTAS 498 Query: 1326 VAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDA 1385 + +G+ANE GIA++DA QGIANEDAA IANE AA GI+ EDA QGIANEDA Sbjct: 499 LTRTPP-RGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDA 557 Query: 1386 AQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANE 1437 AQGIA E G++ ED VQG+ANE QG+A E+ VQG+ANED G+ANE Sbjct: 558 AQGIANEVAAHGISKEDTVQGIANEDAAQGIAKENPVQGVANEDPVQGVANE 609 Score = 565 bits (1455), Expect = e-160 Identities = 335/607 (55%), Positives = 377/607 (62%), Gaps = 90/607 (14%) Query: 1744 EVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARG 1803 E H IANEDA IA EDA+ IANEDAV +AKE AA G+ANE+A H IA DAA Sbjct: 13 EDTVHDIANEDAVYDIATEDAIYDIANEDAVQGIAKEDAAQGIANEEAVHDIANEDAAHV 72 Query: 1804 IANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDP 1863 IANE AAQ IA ED I NEDA G+ NE AAH I+ EDA G+ANE AAQG+A ED Sbjct: 73 IANEDAAQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVAAQGVANEDA 132 Query: 1864 IQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISK 1923 + +ANE DA QGIANEDAAHGIANEDAAQ IANEDAAQDIANEDAAQGISK Sbjct: 133 VHCIANE---------DAAQGIANEDAAHGIANEDAAQDIANEDAAQDIANEDAAQGISK 183 Query: 1924 EDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQG 1983 EDAVQGIAN+DAAQGIAKED VQG+ANED QG+ANE A GIA ED QG+ANED QG Sbjct: 184 EDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGIAKEDPVQGVANEDPVQG 243 Query: 1984 IAHEDAVQGIANEDAVHGVA---------NEDAAHAIAKPDAARGIANEVAAQGIATEDV 2034 +A+EDAVQGIANEDAVHGVA NEDAAHAIAKPDAARGIANEVAAQGIATEDV Sbjct: 244 VANEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDV 303 Query: 2035 ADGIANEDA------------------------------------AHGVANEDA------ 2052 ADGIANEDA AHGVANEDA Sbjct: 304 ADGIANEDAAHGVANEVAAQGVANEDAVEGVANEDAAQGVAKEVTAHGVANEDAVQGVVN 363 Query: 2053 -------------AQAIAKPDAAHGIANE----GIATEDVADGIA-EDAVQG---ITNEE 2091 AQAIAKPDAAHGIANE GIA E IA ED +T Sbjct: 364 EDALHGVVANEDAAQAIAKPDAAHGIANEVTAQGIANEVAIHSIAIEDTTPSRAWLTRSL 423 Query: 2092 AAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVA 2151 ++ + + A +T ++ + + + + Sbjct: 424 PRASLPRMSPTASLRTPPMAS-LTRRPPRPSLSRMPPTASLTRTPSRASLTRSPPRASLT 482 Query: 2152 NEVAAQGVANEDAV--------QGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHG 2203 + +GVANEVEVQGIAHKDAIQGIANEDAA G+ANEVAAHG Sbjct: 483 RTPPTASLTRSPPTASLTRTPPRGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHG 542 Query: 2204 VANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDA 2263 +ANEDAAQG+ANE AAQG+ANE AA G++ E V G+ANEDAA+ +AKE+ QG+ANED Sbjct: 543 IANEDAAQGIANEDAAQGIANEVAAHGISKEDTVQGIANEDAAQGIAKENPVQGVANEDP 602 Query: 2264 AHGIANE 2270 G+ANE Sbjct: 603 VQGVANE 609 Score = 528 bits (1360), Expect = e-149 Identities = 287/529 (54%), Positives = 340/529 (64%), Gaps = 19/529 (3%) Query: 46 ESTPYEDTVHDIANEDA-------DAAHGITNEDAVQGVANEVAAQGVANEDAAH----- 93 +S ED VHDIANEDA DAAH I NEDA GVANEVAAQGVANEDA H Sbjct: 80 QSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVAAQGVANEDAVHCIANE 139 Query: 94 ----GVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEDAVQGVANEDAVQGI 149 G+ANE AAHG+ANEDAAQ +ANE AAQ +ANEDA QG++ EDAVQG+ANEDA QGI Sbjct: 140 DAAQGIANEDAAHGIANEDAAQDIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGI 199 Query: 150 ANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQGISKEDAVQGIANEDAA 209 A ED G+ANED QG+ANEDA Q IAKED Q +ANED QG++ EDAVQGIANEDA Sbjct: 200 AKEDPVQGVANEDPVQGVANEDAVQGIAKEDPVQGVANEDPVQGVANEDAVQGIANEDAV 259 Query: 210 QGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNE 269 G+AKE GVANED +A DA +G+ANEV QG+A ED GIANEDAAHG+ NE Sbjct: 260 HGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANE 319 Query: 270 VAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHG-VANEDAAHA 328 VAA G+ANEDA +G+ANEDAAQG+A E G+ANEDAV GV E A HG VANEDAA A Sbjct: 320 VAAQGVANEDAVEGVANEDAAQGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQA 379 Query: 329 IAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKEVTAHGVANEDAVQGVVN-ED 387 IAKPDAAHGIANEV QGIA E IA ED A + A+ + + Sbjct: 380 IAKPDAAHGIANEVTAQGIANEVAIHSIAIEDTTPSRAWLTRSLPRASLPRMSPTASLRT 439 Query: 388 ALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGI 447 + ++++ + + + + +++ + Sbjct: 440 PPMASLTRRPPRPSLSRMPPTASLTRTPSRASLTRSPPRASLTRTPPTASLTRSPPTASL 499 Query: 448 ANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAA 507 +G+A+E QGIAH+DA+QGIANEDA HG+A EVAAHG+AN+DAA IA DAA Sbjct: 500 -TRTPPRGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAA 558 Query: 508 RGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIA 556 +GIANEVAA GI+ ED GIANEDA G+A E GVANED +A Sbjct: 559 QGIANEVAAHGISKEDTVQGIANEDAAQGIAKENPVQGVANEDPVQGVA 607 Score = 525 bits (1352), Expect = e-148 Identities = 309/538 (57%), Positives = 347/538 (64%), Gaps = 45/538 (8%) Query: 1870 EVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQG 1929 E V +A+EDAV IA EDA + IANEDA QGIA EDAAQ IANE+A I+ EDA Sbjct: 13 EDTVHDIANEDAVYDIATEDAIYDIANEDAVQGIAKEDAAQGIANEEAVHDIANEDAAHV 72 Query: 1930 IANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDA 1989 IAN+DAAQ IA EDAV IANEDA QGI NE AAH IANEDAA G+ANE AAQG+A+EDA Sbjct: 73 IANEDAAQSIANEDAVHDIANEDATQGIVNEDAAHNIANEDAAHGVANEVAAQGVANEDA 132 Query: 1990 VQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVAN 2049 V IANEDA G+ANEDAAH IA DAA+ IANE AAQ IA ED A GI+ EDA G+AN Sbjct: 133 VHCIANEDAAQGIANEDAAHGIANEDAAQDIANEDAAQDIANEDAAQGISKEDAVQGIAN 192 Query: 2050 EDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKED 2109 EDAAQ IAK D G+ANE D VQG+ NE+A Q IAK+D G+ ED Sbjct: 193 EDAAQGIAKEDPVQGVANE-------------DPVQGVANEDAVQGIAKEDPVQGVANED 239 Query: 2110 AAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVA 2169 QGV NE A QG+ANEDA HGVA EVAAHGVANEDAA +A AA+G+ANE A QG+A Sbjct: 240 PVQGVANEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIA 299 Query: 2170 NEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQ 2229 E GIA++DA G+ANE AAQGVANE A GVANEDAAQGVA EV A GVANEDA Q Sbjct: 300 TEDVADGIANEDAAHGVANEVAAQGVANEDAVEGVANEDAAQGVAKEVTAHGVANEDAVQ 359 Query: 2230 GVANEVAVHGV-ANEDAARHMAKEDAAQGIANEDAAHGIANEDAVHGIANEDAVYDIA-- 2286 GV NE A+HGV ANEDAA+ +AK DAA GIANE A GIANE A+H IA ED A Sbjct: 360 GVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVTAQGIANEVAIHSIAIEDTTPSRAWL 419 Query: 2287 ------------------NDTVQGTLTRTLYRTSLMRTPYKASVMRTLYTTSLTRTPYKP 2328 +LTR R SL R P AS+ RT SLTR+P + Sbjct: 420 TRSLPRASLPRMSPTASLRTPPMASLTRRPPRPSLSRMPPTASLTRTPSRASLTRSPPRA 479 Query: 2329 SLTRTLYTTSLMRAPYKTS----PMRALYTTLLMIPTRH-------ANADTVHDIANE 2375 SLTRT T SL R+P S P R + + + H AN D H IANE Sbjct: 480 SLTRTPPTASLTRSPPTASLTRTPPRGVANEVEVQGIAHKDAIQGIANEDAAHGIANE 537 >gi|239746643 PREDICTED: hypothetical protein [Homo sapiens] Length = 454 Score = 367 bits (941), Expect = e-100 Identities = 204/341 (59%), Positives = 228/341 (66%), Gaps = 53/341 (15%) Query: 2081 EDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHG 2140 ED V ITNE DA+H IT EDA G+ NE A +G ANEDAA G+ANE AAHG Sbjct: 124 EDTVHNITNE---------DASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHG 174 Query: 2141 VANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVA 2200 +A+EDAAQG+ANEVAAQG+ANEDA QG+ANE VQGIA++DA GIANEDAA G+ANE A Sbjct: 175 IASEDAAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDA 234 Query: 2201 AHGVANEDAAQGVANEVAAQGVANEDAAQGVANE--------------VAVHGVANEDAA 2246 HG+ANED+ +ANE A +AN D QG + + + Sbjct: 235 VHGIANEDSVYDIANEDAIYDIAN-DTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLT 293 Query: 2247 RHMAKEDAAQGI-----------------------------ANEDAAHGIANEDAVHGIA 2277 R + K + + AN D H IANED+V+ IA Sbjct: 294 RTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIA 353 Query: 2278 NEDAVYDIANDTVQGTLTRTLYRTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTT 2337 NE AVYDIANDTVQGTLTRTLY TSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTT Sbjct: 354 NEGAVYDIANDTVQGTLTRTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTT 413 Query: 2338 SLMRAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDTV 2378 SLM APYKTSPMRALYTTLLMIPTRHAN D VHDIANEDTV Sbjct: 414 SLMTAPYKTSPMRALYTTLLMIPTRHANVDAVHDIANEDTV 454 Score = 353 bits (906), Expect = 1e-96 Identities = 181/236 (76%), Positives = 199/236 (84%), Gaps = 9/236 (3%) Query: 2143 NEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAH 2202 +ED + NE A+ + NEDAV G+ANE A +G ANEDAAQG+ANE AAH Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEA---------ADKGNANEDAAQGIANEDAAH 173 Query: 2203 GVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANED 2262 G+A+EDAAQG+ANEVAAQG+ANEDAAQG+ANE AV G+ANEDAA +A EDAA GIANED Sbjct: 174 GIASEDAAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANED 233 Query: 2263 AAHGIANEDAVHGIANEDAVYDIANDTVQGTLTRTLYRTSLMRTPYKASVMRTLYTTSLT 2322 A HGIANED+V+ IANEDA+YDIANDTVQGTL RTLY TSLMRTPYKA VMRTLY TSLT Sbjct: 234 AVHGIANEDSVYDIANEDAIYDIANDTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLT 293 Query: 2323 RTPYKPSLTRTLYTTSLMRAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDTV 2378 RT YKPSLTRTLYTTSLM APYKTSPMRALYTTLLMIPTRHANADTVHDIANED+V Sbjct: 294 RTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSV 349 Score = 285 bits (730), Expect = 3e-76 Identities = 162/284 (57%), Positives = 187/284 (65%), Gaps = 47/284 (16%) Query: 16 SSEESLVHKDRGDGERPVNVRVVQVAPLRHESTPYEDTVHDIANEDADAAHGITNEDAVQ 75 +SEESLVHKDRGDGERPVNVRVVQVAPLRHESTP+EDTVH+I NEDA +H ITNEDAV Sbjct: 89 ASEESLVHKDRGDGERPVNVRVVQVAPLRHESTPHEDTVHNITNEDA--SHDITNEDAVH 146 Query: 76 GVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANED 135 G+ANE A +G ANEDAA G+ANE AAHG+A+EDAAQG+ANEVAAQG+ANEDA QG+ANED Sbjct: 147 GIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQGIANEDAAQGIANED 206 Query: 136 AVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQG-- 193 AVQG+ANEDA GIANEDAAHGIANEDA GIANED+ DIA EDA DIAN D QG Sbjct: 207 AVQGIANEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIAN-DTVQGTL 265 Query: 194 ------------------------------ISKEDAVQGIANEDAAQGIAKEDPVQGV-- 221 + K + + K P++ + Sbjct: 266 KRTLYTTSLMRTPYKALVMRTLYMTSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRALYT 325 Query: 222 ---------ANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQG 256 AN D V +ANED+V +ANE V +A+ D VQG Sbjct: 326 TLLMIPTRHANADTVHDIANEDSVYHIANEGAVYDIAN-DTVQG 368 Score = 201 bits (510), Expect = 9e-51 Identities = 126/263 (47%), Positives = 147/263 (55%), Gaps = 36/263 (13%) Query: 1324 QGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANE 1383 + HED V I NEDA+H I NEDA GIANE A + ANEDAAQGI+ EDA GIA+E Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASE 178 Query: 1384 DAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGI 1443 DAAQGIA E QG+ANEDA QG+ANE DAVQGIANEDAAHGIANE AAHGI Sbjct: 179 DAAQGIANEVAAQGIANEDAAQGIANE---------DAVQGIANEDAAHGIANEDAAHGI 229 Query: 1444 ANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE--------------VAAHGVA 1489 ANEDA GIANED+ IA+EDA+ IAN D V G K + + Sbjct: 230 ANEDAVHGIANEDSVYDIANEDAIYDIAN-DTVQGTLKRTLYTTSLMRTPYKALVMRTLY 288 Query: 1490 NEDAAHAIAKPDAARGI-ANEVATQGIATED----------VADGIANEDAAHGVANEVA 1538 + KP R + + T T + AN D H +ANE + Sbjct: 289 MTSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDS 348 Query: 1539 AQGIANEVAVHGVAIEDAVQGVV 1561 IANE AV+ +A D VQG + Sbjct: 349 VYHIANEGAVYDIA-NDTVQGTL 370 Score = 196 bits (497), Expect = 3e-49 Identities = 100/142 (70%), Positives = 114/142 (80%), Gaps = 1/142 (0%) Query: 1004 HKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQ 1063 H+D + I NEDA+H I NE A HGIANE A +G ANEDAAQGIANE AAHGI+ EDA Q Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQ 182 Query: 1064 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANED 1123 GIANE AAQGIANEDAAQGIA+EDAVQGIANEDA HG+A E AAHG+ANED V G+ANED Sbjct: 183 GIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGIANED 242 Query: 1124 AVQGVANEVEVQGVAHEDAVQG 1145 +V +ANE + +A+ D VQG Sbjct: 243 SVYDIANEDAIYDIAN-DTVQG 263 Score = 195 bits (495), Expect = 5e-49 Identities = 115/247 (46%), Positives = 144/247 (58%), Gaps = 9/247 (3%) Query: 933 QDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQG 992 +D H+ITNEDA+ + NEDA HG+ANE A +G ANE AAQG+ANEDA HG+A+EDA QG Sbjct: 124 EDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQG 183 Query: 993 VANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVA 1052 +ANEV QGIA++DA QGIANEDA GIANE AAHGIANEDAA GIANEDA GIANE + Sbjct: 184 IANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGIANEDS 243 Query: 1053 AHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANE-----DAVHGVAKEVAA 1107 + I+ EDA+ IAN D QG + + + K Sbjct: 244 VYDIANEDAIYDIAN-DTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLTRTLYKPSLT 302 Query: 1108 HGVANEDPVQGVANEDAVQGVANEVEVQGVAH--EDAVQGIANEDAAHGIANEVAAHGIA 1165 + + ++ + + + H D V IANED+ + IANE A + IA Sbjct: 303 RTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIANEGAVYDIA 362 Query: 1166 NEDAAQG 1172 N D QG Sbjct: 363 N-DTVQG 368 Score = 193 bits (491), Expect = 1e-48 Identities = 123/268 (45%), Positives = 142/268 (52%), Gaps = 50/268 (18%) Query: 1135 QGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANE 1194 + HED V I NEDA+H I NE A HGIANE A +G ANEDAAQGIA+EDA GIA+E Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASE 178 Query: 1195 DAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGV 1254 DA G+A EVAA G+ANEDAA +GIANE A QGIA ED A GIANEDAAHG+ Sbjct: 179 DAAQGIANEVAAQGIANEDAA---------QGIANEDAVQGIANEDAAHGIANEDAAHGI 229 Query: 1255 ANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVA----- 1309 ANE A HGI+ ED+V IANEDA IA D VQG P + + Sbjct: 230 ANEDAVHGIANEDSVYDIANEDAIYDIA-NDTVQGTLKRTLYTTSLMRTPYKALVMRTLY 288 Query: 1310 ---------------------------NEDPIQGVANEVEVQGVAHEDAVQGIANEDAAH 1342 P++ + + + H AN D H Sbjct: 289 MTSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRH-------ANADTVH 341 Query: 1343 GIANEDAAQGIANEDAAQDIANEDAAQG 1370 IANED+ IANE A DIAN D QG Sbjct: 342 DIANEDSVYHIANEGAVYDIAN-DTVQG 368 Score = 192 bits (487), Expect = 4e-48 Identities = 115/248 (46%), Positives = 138/248 (55%), Gaps = 42/248 (16%) Query: 1865 QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKE 1924 + +E V + +EDA I NEDA HGIANE A +G ANEDAAQ IANEDAA GI+ E Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASE 178 Query: 1925 DAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGI 1984 DA QGIAN+ AAQGIA EDA QGIANEDA QGIANE AAHGIANEDAA GIANEDA GI Sbjct: 179 DAAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGI 238 Query: 1985 AHEDAVQGIANEDAVHGVANE-------------------------------DAAHAIAK 2013 A+ED+V IANEDA++ +AN+ + K Sbjct: 239 ANEDSVYDIANEDAIYDIANDTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLTRTLYK 298 Query: 2014 PDAARGI-----------ANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAA 2062 P R + + + A + AN D H +ANED+ IA A Sbjct: 299 PSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIANEGAV 358 Query: 2063 HGIANEGI 2070 + IAN+ + Sbjct: 359 YDIANDTV 366 Score = 191 bits (486), Expect = 6e-48 Identities = 120/257 (46%), Positives = 145/257 (56%), Gaps = 27/257 (10%) Query: 1040 NEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVH 1099 +ED I NE A+H I+ EDAV GIANE A +G ANEDAAQGIA+EDA GIA+EDA Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQ 182 Query: 1100 GVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEV 1159 G+A EVAA G+ANED QG+ANEDAVQG+AN EDA GIANEDAAHGIANE Sbjct: 183 GIANEVAAQGIANEDAAQGIANEDAVQGIAN---------EDAAHGIANEDAAHGIANED 233 Query: 1160 AAHGIANEDAAQGIANEDAAQGIAHEDAVQG-----IANEDAVHGVAKEVAAHGVANEDA 1214 A HGIANED+ IANEDA IA+ D VQG + + K + + Sbjct: 234 AVHGIANEDSVYDIANEDAIYDIAN-DTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSL 292 Query: 1215 AHAIAKPDAARGI-----------ANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGI 1263 + KP R + + + A + AN D H +ANE + + I Sbjct: 293 TRTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHI 352 Query: 1264 SKEDAVQGIANEDAAQG 1280 + E AV IAN D QG Sbjct: 353 ANEGAVYDIAN-DTVQG 368 Score = 191 bits (484), Expect = 1e-47 Identities = 116/253 (45%), Positives = 140/253 (55%), Gaps = 7/253 (2%) Query: 1874 QGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQ 1933 + HED V I NEDA+H I NEDA GIANE A + ANEDAAQGI+ EDA GIA++ Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASE 178 Query: 1934 DAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGI 1993 DAAQGIA E A QGIANEDAAQGIANE A GIANEDAA GIANEDAA GIA+EDAV GI Sbjct: 179 DAAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGI 238 Query: 1994 ANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAA 2053 ANED+V+ +ANEDA + IA D +G + T + + Sbjct: 239 ANEDSVYDIANEDAIYDIAN-DTVQGTLKRT----LYTTSLMRTPYKALVMRTLYMTSLT 293 Query: 2054 QAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQG 2113 + + KP + + T + A A D H I ED+ Sbjct: 294 RTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANA--DTVHDIANEDSVYH 351 Query: 2114 VTNEVAAQGVANE 2126 + NE A +AN+ Sbjct: 352 IANEGAVYDIAND 364 Score = 188 bits (477), Expect = 6e-47 Identities = 115/273 (42%), Positives = 143/273 (52%), Gaps = 27/273 (9%) Query: 693 NEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAH 752 +ED I NE A+H I+ EDAV GIANE A +G A+EDA QGIANEDA HG+A E AA Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQ 182 Query: 753 GVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANED 812 G+ANE QG+ANED QG+ANE DAVQGIANEDAAHGIANE AAHG+ANED Sbjct: 183 GIANEVAAQGIANEDAAQGIANE---------DAVQGIANEDAAHGIANEDAAHGIANED 233 Query: 813 AAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVV 872 A G+ANED+ +ANEDA++ +AN D QG K + +V + Sbjct: 234 AVHGIANEDSVYDIANEDAIYDIAN-DTVQGTLKRTLYTTSLMRTPYKALVMR-----TL 287 Query: 873 ANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAK 932 + + KP + + + H A Sbjct: 288 YMTSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRH-----------AN 336 Query: 933 QDAAHSITNEDAAQGVANEDAAHGVANEDAAQG 965 D H I NED+ +ANE A + +AN D QG Sbjct: 337 ADTVHDIANEDSVYHIANEGAVYDIAN-DTVQG 368 Score = 186 bits (471), Expect = 3e-46 Identities = 117/250 (46%), Positives = 143/250 (57%), Gaps = 12/250 (4%) Query: 385 NEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAV 444 +ED +H + NEDA+ I DA HGIANE A G ANEDAAQGIANE AAHGI+ EDA Sbjct: 123 HEDTVHNIT-NEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASEDAA 181 Query: 445 QGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKP 504 QGIANE AAQGIA+EDAAQGIA+EDAVQGIANEDA HG+A E AAHG+AN+DA H IA Sbjct: 182 QGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGIANE 241 Query: 505 DAARGIANEVAAQGIATEDVADGIA----NEDAVHGVANEVAAHGVANEDAAHAIAKPDA 560 D+ IANE A IA + V + + + + + KP Sbjct: 242 DSVYDIANEDAIYDIANDTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLTRTLYKPSL 301 Query: 561 AHGI-ANEVATQGIATEDVA---DGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVH 616 + + T T + + H AN VH +A ED+V +ANE AV+ Sbjct: 302 TRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRH--ANADTVHDIANEDSVYHIANEGAVY 359 Query: 617 GVANEDAAQG 626 +AN D QG Sbjct: 360 DIAN-DTVQG 368 Score = 186 bits (471), Expect = 3e-46 Identities = 114/247 (46%), Positives = 136/247 (55%), Gaps = 27/247 (10%) Query: 1239 EDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQG 1298 ED I NEDA+H + NE A HGI+ E A +G ANEDAAQGIA EDA GIA+EDAAQG Sbjct: 124 EDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQG 183 Query: 1299 IAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDA 1358 IA E QG+ANED QG+ANE VQG+A+EDA GIANEDAAHGIANEDA GIANED+ Sbjct: 184 IANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGIANEDS 243 Query: 1359 AQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVA-------------NEDAVQ 1405 DIANEDA I+ D VQG P + + + ++ Sbjct: 244 VYDIANEDAIYDIA-NDTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLTRTLYKPSLT 302 Query: 1406 GVANEVEVQGVAHEDAVQGI------------ANEDAAHGIANEVAAHGIANEDAAQGIA 1453 + ++ + AN D H IANE + + IANE A IA Sbjct: 303 RTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIANEGAVYDIA 362 Query: 1454 NEDAAQG 1460 N D QG Sbjct: 363 N-DTVQG 368 Score = 185 bits (469), Expect = 5e-46 Identities = 103/179 (57%), Positives = 125/179 (69%), Gaps = 1/179 (0%) Query: 940 TNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEV 999 T E + + + ++D G + + + +ED VH + NEDA + NE V Sbjct: 86 TLEASEESLVHKDRGDGERPVNVRVVQVAPLRHESTPHEDTVHNITNEDASHDITNEDAV 145 Query: 1000 QGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKE 1059 GIA++ A +G ANEDAA GIANE AAHGIA+EDAAQGIANE AAQGIANE AA GI+ E Sbjct: 146 HGIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQGIANEDAAQGIANE 205 Query: 1060 DAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQG 1118 DAVQGIANEDAA GIANEDAA GIA+EDAV GIANED+V+ +A E A + +AN D VQG Sbjct: 206 DAVQGIANEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIAN-DTVQG 263 Score = 185 bits (469), Expect = 5e-46 Identities = 96/147 (65%), Positives = 111/147 (75%), Gaps = 1/147 (0%) Query: 1585 HSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISK 1644 H +ED I DA+H I NE A H IAN+ A +G AN+DAAQGIANE AAHGI+ Sbjct: 118 HESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIAS 177 Query: 1645 EDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQG 1704 EDA QGIANE AAQGIANEDAAQGIA+EDAVQGIANEDA HG+A E AAHG+ANED V G Sbjct: 178 EDAAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHG 237 Query: 1705 VANEDAVQGVANEVEVQGVAHEDAVQG 1731 +ANED+V +ANE + +A+ D VQG Sbjct: 238 IANEDSVYDIANEDAIYDIAN-DTVQG 263 Score = 184 bits (468), Expect = 7e-46 Identities = 115/282 (40%), Positives = 146/282 (51%), Gaps = 34/282 (12%) Query: 1609 EVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQG 1668 E + S+ +KD G + + ED V I NEDA+ I NEDA G Sbjct: 88 EASEESLVHKDRGDGERPVNVRVVQVAPLRHESTPHEDTVHNITNEDASHDITNEDAVHG 147 Query: 1669 IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDA 1728 IA+E A +G ANEDA G+A E AAHG+A+ED QG+ANE A QG+ANE QG+A+EDA Sbjct: 148 IANEAADKGNANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQGIANEDAAQGIANEDA 207 Query: 1729 VQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVA---------- 1778 VQGIANEDAAHGI NE AAHGIANEDA GIA+ED+V IANEDA++ +A Sbjct: 208 VQGIANEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIANDTVQGTLKR 267 Query: 1779 ------------KEVAAHGVANEDAAHAIAKPDAARGI-----------ANEVAAQGIAT 1815 K + + + KP R + + + A Sbjct: 268 TLYTTSLMRTPYKALVMRTLYMTSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTL 327 Query: 1816 EDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQG 1857 + N D H +ANE + + I+ E AV IAN D QG Sbjct: 328 LMIPTRHANADTVHDIANEDSVYHIANEGAVYDIAN-DTVQG 368 Score = 184 bits (468), Expect = 7e-46 Identities = 109/243 (44%), Positives = 135/243 (55%), Gaps = 26/243 (10%) Query: 169 NEDAAQDIAKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQ 228 +ED +I EDA+ DI NEDA GI+ E A +G ANEDAAQGIA ED G+A+ED Q Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQ 182 Query: 229 GVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANED 288 G+ANE A QG+ANE QG+A+EDAVQGIANEDAAHGI NE AAHGIANEDA GIANED Sbjct: 183 GIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGIANED 242 Query: 289 AAQGIAHEDAVQGIANEDAVHGVAKE--------------VAAHGVANEDAAHAIAKPDA 334 + IA+EDA+ IAN D V G K + + + KP Sbjct: 243 SVYDIANEDAIYDIAN-DTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLTRTLYKPSL 301 Query: 335 AHGI-ANEVATQGIATED----------VADGIANEDAAHGVAKEVTAHGVANEDAVQGV 383 + + T T + AN D H +A E + + +ANE AV + Sbjct: 302 TRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIANEGAVYDI 361 Query: 384 VNE 386 N+ Sbjct: 362 AND 364 Score = 184 bits (467), Expect = 9e-46 Identities = 112/248 (45%), Positives = 137/248 (55%), Gaps = 27/248 (10%) Query: 1229 NEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQ 1288 +E I ED + I NEDA HG+ANE A G + EDA QGIANEDAA GIA EDA Q Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQ 182 Query: 1289 GIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANED 1348 GIANE AAQGIA ED QG+ANED +QG+ANE G+A+EDA GIANEDA HGIANED Sbjct: 183 GIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGIANED 242 Query: 1349 AAQGIANEDAAQDIANEDAAQGISKED--------------AVQGIANEDAAQGIAKEDP 1394 + IANEDA DIAN D QG K ++ + + + K Sbjct: 243 SVYDIANEDAIYDIAN-DTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLTRTLYKPSL 301 Query: 1395 VQGVANEDAVQGVANEVEVQGV-----------AHEDAVQGIANEDAAHGIANEVAAHGI 1443 + + + ++ + A+ D V IANED+ + IANE A + I Sbjct: 302 TRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIANEGAVYDI 361 Query: 1444 ANEDAAQG 1451 AN D QG Sbjct: 362 AN-DTVQG 368 Score = 183 bits (465), Expect = 2e-45 Identities = 114/252 (45%), Positives = 139/252 (55%), Gaps = 17/252 (6%) Query: 1414 QGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANE 1473 + HED V I NEDA+H I NE A HGIANE A +G ANEDAAQGIA+EDA GIA+E Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASE 178 Query: 1474 DAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGV 1533 DA G+A EVAA G+ANEDAA IA DA +GIANE A GIA ED A GIANEDA HG+ Sbjct: 179 DAAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGI 238 Query: 1534 ANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVV-------------N 1580 ANE + IANE A++ +A D VQG +K + +V Sbjct: 239 ANEDSVYDIANEDAIYDIA-NDTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLTRTLY 297 Query: 1581 EDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSI--ANKDAAQGIANQDAAQGIANEVA 1638 + +L + A K + + AN D IAN+D+ IANE A Sbjct: 298 KPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIANEGA 357 Query: 1639 AHGISKEDAVQG 1650 + I+ D VQG Sbjct: 358 VYDIA-NDTVQG 368 Score = 183 bits (464), Expect = 2e-45 Identities = 96/146 (65%), Positives = 109/146 (74%), Gaps = 1/146 (0%) Query: 991 QGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANE 1050 + +E V I ++DA I NEDA HGIANE A G ANEDAAQGIANEDAA GIA+E Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASE 178 Query: 1051 VAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGV 1110 AA GI+ E A QGIANEDAAQGIANEDA QGIA+EDA GIANEDA HG+A E A HG+ Sbjct: 179 DAAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGI 238 Query: 1111 ANEDPVQGVANEDAVQGVANEVEVQG 1136 ANED V +ANEDA+ +AN+ VQG Sbjct: 239 ANEDSVYDIANEDAIYDIANDT-VQG 263 Score = 181 bits (460), Expect = 6e-45 Identities = 109/252 (43%), Positives = 139/252 (55%), Gaps = 17/252 (6%) Query: 246 QGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANE 305 + HED V I NEDA+H ITNE A HGIANE A +G ANEDAAQGIA+EDA GIA+E Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASE 178 Query: 306 DAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGV 365 DA G+A EVAA G+ANEDAA IA DA GIANE A GIA ED A GIANEDA HG+ Sbjct: 179 DAAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGI 238 Query: 366 AKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDA 425 A E + + +ANEDA+ + N D + G + ++ + + + + Sbjct: 239 ANEDSVYDIANEDAIYDIAN-DTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLTRTLY 297 Query: 426 AQGIANEVAAHGIS----KEDAVQGI-----------ANEDAAQGIAHEDAAQGIAHEDA 470 + + + K ++ + AN D IA+ED+ IA+E A Sbjct: 298 KPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIANEGA 357 Query: 471 VQGIANEDAVHG 482 V IAN D V G Sbjct: 358 VYDIAN-DTVQG 368 Score = 181 bits (460), Expect = 6e-45 Identities = 111/251 (44%), Positives = 134/251 (53%), Gaps = 16/251 (6%) Query: 1721 QGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKE 1780 + HED V I NEDA+H ITNE A HGIANE A +G A+EDA QGIANEDA H +A E Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASE 178 Query: 1781 VAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGI 1840 AA G+ANE AA IA DAA+GIANE A QGIA ED A GI NEDAAHG+ANE A HGI Sbjct: 179 DAAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGI 238 Query: 1841 SKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAA 1900 + ED+V IANEDA IA D +QG + + + Sbjct: 239 ANEDSVYDIANEDAIYDIA-NDTVQGTLKRTLYTTSLMRTPYKAL----VMRTLYMTSLT 293 Query: 1901 QGIANEDAAQDIANEDAAQGISKEDAVQGI-----------ANQDAAQGIAKEDAVQGIA 1949 + + + + K ++ + AN D IA ED+V IA Sbjct: 294 RTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIA 353 Query: 1950 NEDAAQGIANE 1960 NE A IAN+ Sbjct: 354 NEGAVYDIAND 364 Score = 180 bits (457), Expect = 1e-44 Identities = 93/142 (65%), Positives = 105/142 (73%) Query: 652 HGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISK 711 H +ED I DA+H I NE A HGIANE A +G ANEDAAQGIANE AAHGI+ Sbjct: 118 HESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIAS 177 Query: 712 EDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQG 771 EDA QGIANE AAQGIA+EDA QGIANEDAV G+A E AAHG+ANED G+ANED V G Sbjct: 178 EDAAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHG 237 Query: 772 VANEVEVQGIAHEDAVQGIANE 793 +ANE V IA+EDA+ IAN+ Sbjct: 238 IANEDSVYDIANEDAIYDIAND 259 Score = 180 bits (457), Expect = 1e-44 Identities = 112/251 (44%), Positives = 133/251 (52%), Gaps = 27/251 (10%) Query: 1776 SVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEV 1835 S E H + NEDA+H I DA GIANE A +G A ED A GI NEDAAHG+A+E Sbjct: 120 STPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASED 179 Query: 1836 AAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIA 1895 AA GI+ E A QGIANEDAAQGIA ED +QG+ANE G+A+EDA GIANEDA HGIA Sbjct: 180 AAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGIA 239 Query: 1896 NEDAAQGIANEDAAQDIANEDAAQGISKED--------------AVQGIANQDAAQGIAK 1941 NED+ IANEDA DIAN D QG K ++ + + + K Sbjct: 240 NEDSVYDIANEDAIYDIAN-DTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLTRTLYK 298 Query: 1942 EDAVQGIANEDAAQGIANEVAAHGI-----------ANEDAAQGIANEDAAQGIAHEDAV 1990 + + + AN D IANED+ IA+E AV Sbjct: 299 PSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIANEGAV 358 Query: 1991 QGIANEDAVHG 2001 IAN D V G Sbjct: 359 YDIAN-DTVQG 368 Score = 180 bits (457), Expect = 1e-44 Identities = 119/256 (46%), Positives = 137/256 (53%), Gaps = 35/256 (13%) Query: 215 EDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHG 274 ED V + NED + NEDAV G+ANE +G A+EDA QGIANEDAAHGI +E AA G Sbjct: 124 EDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQG 183 Query: 275 IANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDA 334 IANE AAQGIANEDAAQGIA+EDAVQGIANEDA AHG+ANEDAAH IA DA Sbjct: 184 IANEVAAQGIANEDAAQGIANEDAVQGIANEDA---------AHGIANEDAAHGIANEDA 234 Query: 335 AHGIANEVATQGIATEDVADGIANEDAAHGVAKEVTAHGVANEDAVQGVV---------- 384 HGIANE + IA ED IAN D G K + +V Sbjct: 235 VHGIANEDSVYDIANEDAIYDIAN-DTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLT 293 Query: 385 ---NEDALHGVVANEDAAQAIAKPDAAHGI-----------ANEVAAHGIANEDAAQGIA 430 + +L + A K + AN H IANED+ IA Sbjct: 294 RTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIA 353 Query: 431 NEVAAHGISKEDAVQG 446 NE A + I+ D VQG Sbjct: 354 NEGAVYDIA-NDTVQG 368 Score = 180 bits (457), Expect = 1e-44 Identities = 112/255 (43%), Positives = 141/255 (55%), Gaps = 26/255 (10%) Query: 907 EDVADGIA-KDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQG 965 ED I +DA+H IT E+A IA + A NEDAAQG+ANEDAAHG+A+EDAAQG Sbjct: 124 EDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQG 183 Query: 966 VANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVA 1025 +ANEVAAQG+ANEDA G+ANEDAVQG+ANE DA GIANEDAAHGIANE A Sbjct: 184 IANEVAAQGIANEDAAQGIANEDAVQGIANE---------DAAHGIANEDAAHGIANEDA 234 Query: 1026 AHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANED----AAQGIANEDAAQ 1081 HGIANED+ IANEDA IAN+ + + + + + + Sbjct: 235 VHGIANEDSVYDIANEDAIYDIANDTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLTR 294 Query: 1082 GIAHEDAVQGIANEDAVHGVAKEVAAHGV-----------ANEDPVQGVANEDAVQGVAN 1130 + + + + K + AN D V +ANED+V +AN Sbjct: 295 TLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIAN 354 Query: 1131 EVEVQGVAHEDAVQG 1145 E V +A+ D VQG Sbjct: 355 EGAVYDIAN-DTVQG 368 Score = 179 bits (455), Expect = 2e-44 Identities = 116/282 (41%), Positives = 145/282 (51%), Gaps = 33/282 (11%) Query: 450 EDAAQGIAHEDAAQGIAHEDA----VQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPD 505 E + + + H+D G + V + +E H E H + N+DA+H I D Sbjct: 88 EASEESLVHKDRGDGERPVNVRVVQVAPLRHESTPH----EDTVHNITNEDASHDITNED 143 Query: 506 AARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIA 565 A GIANE A +G A ED A GIANEDA HG+A+E AA G+ANE AA IA DAA GIA Sbjct: 144 AVHGIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQGIANEDAAQGIA 203 Query: 566 NEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQ 625 NE A QGIA ED A GIANEDAAHG+ANE AVHG+A ED+V +ANEDA++ +AN D Q Sbjct: 204 NEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIAN-DTVQ 262 Query: 626 GIAKEVTAHGVANEDAVQGVV-------------NEDALHGVVANEDAAQAIAKPDAAHG 672 G K + +V + +L + A K Sbjct: 263 GTLKRTLYTTSLMRTPYKALVMRTLYMTSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRA 322 Query: 673 I-----------ANEVAAHGIANEDAAQGIANEDAAQGIANE 703 + AN H IANED+ IANE A IAN+ Sbjct: 323 LYTTLLMIPTRHANADTVHDIANEDSVYHIANEGAVYDIAND 364 Score = 178 bits (452), Expect = 5e-44 Identities = 107/248 (43%), Positives = 133/248 (53%), Gaps = 15/248 (6%) Query: 120 QGVANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKE 179 + +ED V + NEDA + NEDAV GIANE A G ANEDAAQGIANEDAA IA E Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASE 178 Query: 180 DAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGV 239 DAAQ IANE AAQGI+ EDA QGIANEDA QGIA ED G+ANED G+ANEDAV G+ Sbjct: 179 DAAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGI 238 Query: 240 ANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANED----AAQGIANEDAAQGIAH 295 ANE V +A+EDA+ IAN+ + + + + + + + Sbjct: 239 ANEDSVYDIANEDAIYDIANDTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLTRTLYK 298 Query: 296 EDAVQGIANEDAVHGVAKEVAAHGV-----------ANEDAAHAIAKPDAAHGIANEVAT 344 + + + K + AN D H IA D+ + IANE A Sbjct: 299 PSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIANEGAV 358 Query: 345 QGIATEDV 352 IA + V Sbjct: 359 YDIANDTV 366 Score = 178 bits (452), Expect = 5e-44 Identities = 95/142 (66%), Positives = 109/142 (76%), Gaps = 2/142 (1%) Query: 630 EVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQ 689 E T H + NEDA + NEDA+HG+ ANE A + A DAA GIANE AAHGIA+EDAAQ Sbjct: 124 EDTVHNITNEDASHDITNEDAVHGI-ANEAADKGNANEDAAQGIANEDAAHGIASEDAAQ 182 Query: 690 GIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEV 749 GIANE AAQGIANE AA GI+ EDAVQGIANEDAA GIA+EDA GIANEDAVHG+A E Sbjct: 183 GIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGIANED 242 Query: 750 AAHGVANEDPVQGVANEDVVQG 771 + + +ANED + +AN D VQG Sbjct: 243 SVYDIANEDAIYDIAN-DTVQG 263 Score = 177 bits (448), Expect = 1e-43 Identities = 91/142 (64%), Positives = 105/142 (73%), Gaps = 1/142 (0%) Query: 607 QGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAK 666 + +ED VH + NEDA+ I E HG+ANE A +G NEDA G +ANEDAA IA Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQG-IANEDAAHGIAS 177 Query: 667 PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG 726 DAA GIANEVAA GIANEDAAQGIANEDA QGIANE AAHGI+ EDA GIANEDA G Sbjct: 178 EDAAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHG 237 Query: 727 IAHEDAVQGIANEDAVHGVAKE 748 IA+ED+V IANEDA++ +A + Sbjct: 238 IANEDSVYDIANEDAIYDIAND 259 Score = 176 bits (445), Expect = 3e-43 Identities = 116/277 (41%), Positives = 144/277 (51%), Gaps = 30/277 (10%) Query: 1718 VEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSV 1777 V+V + HE +ED H ITNE A+H I NEDA GIA+E A +G ANEDA Sbjct: 111 VQVAPLRHEST----PHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDA---- 162 Query: 1778 AKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAA 1837 A G+ANEDAAH IA DAA+GIANEVAAQGIA ED A GI NEDA G+ANE AA Sbjct: 163 -----AQGIANEDAAHGIASEDAAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAA 217 Query: 1838 HGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANE 1897 HGI+ EDA GIANEDA GIA ED + +ANE + +A+ D VQG Sbjct: 218 HGIANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIAN-DTVQGTLKRTLYTTSLMR 276 Query: 1898 DAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGI--------- 1948 + + + + + + K + + K ++ + Sbjct: 277 TPYKAL----VMRTLYMTSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPT 332 Query: 1949 --ANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQG 1983 AN D IANE + + IANE A IAN D QG Sbjct: 333 RHANADTVHDIANEDSVYHIANEGAVYDIAN-DTVQG 368 Score = 172 bits (437), Expect = 3e-42 Identities = 88/142 (61%), Positives = 103/142 (72%), Gaps = 1/142 (0%) Query: 684 NEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVH 743 +ED I NEDA+ I NE A HGI+ E A +G ANEDAAQGIA+EDA GIA+EDA Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQ 182 Query: 744 GVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEV 803 G+A EVAA G+ANED QG+ANED VQG+ANE GIA+EDA GIANEDA HGIANE Sbjct: 183 GIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGIANED 242 Query: 804 AAHGVANEDAAQGVANEDAAQG 825 + + +ANEDA +AN D QG Sbjct: 243 SVYDIANEDAIYDIAN-DTVQG 263 Score = 171 bits (433), Expect = 8e-42 Identities = 110/248 (44%), Positives = 132/248 (53%), Gaps = 18/248 (7%) Query: 1761 HEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVAD 1820 HED V I NEDA H + E A HG+ANE A A DAA+GIANE AA GIA+ED A Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQ 182 Query: 1821 GIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHED 1880 GI NE AA G+ANE AA GI+ EDAVQGIANEDAA GIA ED G+ANE V G+A+ED Sbjct: 183 GIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGIANED 242 Query: 1881 AVQGIANEDAAHGIANEDAAQGIANED--------------AAQDIANEDAAQGISKEDA 1926 +V IANEDA + IAN D QG + + + + K Sbjct: 243 SVYDIANEDAIYDIAN-DTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLTRTLYKPSL 301 Query: 1927 VQGIANQDAAQGIAKEDAVQGIANE--DAAQGIANEVAAHGIANEDAAQGIANEDAAQGI 1984 + + K ++ + AN H IANED+ IANE A I Sbjct: 302 TRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIANEGAVYDI 361 Query: 1985 AHEDAVQG 1992 A+ D VQG Sbjct: 362 AN-DTVQG 368 Score = 168 bits (425), Expect = 7e-41 Identities = 107/246 (43%), Positives = 126/246 (51%), Gaps = 35/246 (14%) Query: 505 DAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGI 564 D I NE A+ I ED GIANE A G ANE AA G+ANEDAAH IA DAA GI Sbjct: 125 DTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQGI 184 Query: 565 ANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAA 624 ANEVA QGIA ED A GIANEDA G+ANE A HG+A EDA G+ANEDAVHG+ANED+ Sbjct: 185 ANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGIANEDSV 244 Query: 625 QGIAKEVTAHGVANEDAVQGVVNEDA-------------LHGVVANEDAAQAIAKPDAAH 671 IA E + +AN D VQG + + + + + KP Sbjct: 245 YDIANEDAIYDIAN-DTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLTRTLYKPSLTR 303 Query: 672 GIANE--------------------VAAHGIANEDAAQGIANEDAAQGIANEVAAHGISK 711 + + AN D IANED+ IANE A + I+ Sbjct: 304 TLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIANEGAVYDIA- 362 Query: 712 EDAVQG 717 D VQG Sbjct: 363 NDTVQG 368 Score = 166 bits (420), Expect = 3e-40 Identities = 104/247 (42%), Positives = 127/247 (51%), Gaps = 53/247 (21%) Query: 1712 QGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANE 1771 + +E V + +EDA I NEDA HGI NE A G ANEDAAQGIA+EDA GIA+E Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASE 178 Query: 1772 DAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGV 1831 DA +A EVAA G+ANEDAA IA DA +GIANE AA GIA ED A GI NEDA HG+ Sbjct: 179 DAAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHGI 238 Query: 1832 ANEVAAHGISKEDAVQGIANEDAAQGIAKE------------------------------ 1861 ANE + + I+ EDA+ IAN D QG K Sbjct: 239 ANEDSVYDIANEDAIYDIAN-DTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLTRTLY 297 Query: 1862 --------------------DPIQGVANEVEVQGVAHEDA--VQGIANEDAAHGIANEDA 1899 P++ + + + H +A V IANED+ + IANE A Sbjct: 298 KPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIANEGA 357 Query: 1900 AQGIANE 1906 IAN+ Sbjct: 358 VYDIAND 364 Score = 162 bits (411), Expect = 3e-39 Identities = 107/266 (40%), Positives = 135/266 (50%), Gaps = 32/266 (12%) Query: 761 QGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANE 820 + +ED V + NE I +EDAV GIANE A G ANE AA G+ANEDAA G+A+E Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASE 178 Query: 821 DAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQA 880 DAAQG+ANE A G+ANEDAAQG+A NEDAVQG+ NE+A HG +ANEDAA Sbjct: 179 DAAQGIANEVAAQGIANEDAAQGIA---------NEDAVQGIANEDAAHG-IANEDAAHG 228 Query: 881 IAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEE--------------A 926 IA DA HGIANE + IA ED IA D G K Sbjct: 229 IANEDAVHGIANED-----SVYDIANEDAIYDIANDTVQGTLKRTLYTTSLMRTPYKALV 283 Query: 927 AQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGV--ANEDAVHGV 984 + + ++ + + + + + AN D VH + Sbjct: 284 MRTLYMTSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDI 343 Query: 985 ANEDAVQGVANEVEVQGIAHKDAIQG 1010 ANED+V +ANE V IA+ D +QG Sbjct: 344 ANEDSVYHIANEGAVYDIAN-DTVQG 368 Score = 162 bits (409), Expect = 5e-39 Identities = 105/253 (41%), Positives = 134/253 (52%), Gaps = 23/253 (9%) Query: 869 HGVVANEDAAQAIAKPDAAHGIANE----GVANEVAAQGIATEDVADGIA-KDAAHGITK 923 H +ED I DA+H I NE G+ANE A +G A ED A GIA +DAAHGI Sbjct: 118 HESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIAS 177 Query: 924 EEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHG 983 E+AAQ IA + AA I NEDAAQG+ANEDA G+ANEDAA G+ANE AA G+ANEDAVHG Sbjct: 178 EDAAQGIANEVAAQGIANEDAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHG 237 Query: 984 VANEDAVQGVANEVEVQGIAHKDAIQG-----IANEDAAHGIANEVAAHGIANEDAAQGI 1038 +ANED+V +ANE + IA+ D +QG + + + + + Sbjct: 238 IANEDSVYDIANEDAIYDIAN-DTVQGTLKRTLYTTSLMRTPYKALVMRTLYMTSLTRTL 296 Query: 1039 ANEDAAQGIANEVAAHGISKEDAVQGI-----------ANEDAAQGIANEDAAQGIAHED 1087 + + K ++ + AN D IANED+ IA+E Sbjct: 297 YKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYHIANEG 356 Query: 1088 AVQGIANEDAVHG 1100 AV IAN D V G Sbjct: 357 AVYDIAN-DTVQG 368 Score = 161 bits (407), Expect = 8e-39 Identities = 85/142 (59%), Positives = 99/142 (69%), Gaps = 6/142 (4%) Query: 1995 NEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQ 2054 +ED VH + NEDA+H I DA GIANE A +G A ED A GIANEDAAHG+A+EDAAQ Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAADKGNANEDAAQGIANEDAAHGIASEDAAQ 182 Query: 2055 AIAKPDAAHGIANEGIATEDVADGIA-EDAVQGITNEEAAQAIAKQDAAHGITKEDAAQG 2113 IA AA GIANE D A GIA EDAVQGI NE+AA IA +DAAHGI EDA G Sbjct: 183 GIANEVAAQGIANE-----DAAQGIANEDAVQGIANEDAAHGIANEDAAHGIANEDAVHG 237 Query: 2114 VTNEVAAQGVANEDAAHGVANE 2135 + NE + +ANEDA + +AN+ Sbjct: 238 IANEDSVYDIANEDAIYDIAND 259 Score = 34.3 bits (77), Expect = 1.5 Identities = 16/37 (43%), Positives = 22/37 (59%), Gaps = 1/37 (2%) Query: 827 ANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVV 863 AN D VH +ANED+ +A E + + N D VQG + Sbjct: 335 ANADTVHDIANEDSVYHIANEGAVYDIAN-DTVQGTL 370 Score = 33.9 bits (76), Expect = 2.0 Identities = 18/38 (47%), Positives = 22/38 (57%), Gaps = 1/38 (2%) Query: 1994 ANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIAT 2031 AN D VH +ANED+ + IA A IAN+ QG T Sbjct: 335 ANADTVHDIANEDSVYHIANEGAVYDIAND-TVQGTLT 371 Score = 32.3 bits (72), Expect = 5.7 Identities = 14/37 (37%), Positives = 21/37 (56%) Query: 818 ANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVT 854 AN D +ANED+V+ +ANE A +A + +T Sbjct: 335 ANADTVHDIANEDSVYHIANEGAVYDIANDTVQGTLT 371 >gi|239746650 PREDICTED: hypothetical protein [Homo sapiens] Length = 486 Score = 362 bits (930), Expect = 2e-99 Identities = 191/305 (62%), Positives = 220/305 (72%), Gaps = 23/305 (7%) Query: 2088 TNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAA 2147 T E + +++ +D G + + + +ED H + NE A+H + NEDA Sbjct: 86 TLEASEESLVHKDRGDGERPVNVKVVQVAPLRRESTPHEDTVHNITNEDASHDITNEDAV 145 Query: 2148 QGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANE 2207 G+ANE A +G+ANEDA QG+ANE DA GIA+EDAAQG+ANEVAA G+ANE Sbjct: 146 HGIANEAADKGIANEDAAQGIANE---------DAAHGIASEDAAQGIANEVAAQGIANE 196 Query: 2208 DAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANE------ 2261 DAAQG+A E AA G+ANEDAA G+ANE AVHG+ANED+ +A EDA IAN+ Sbjct: 197 DAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIANDTVQGTL 256 Query: 2262 --------DAAHGIANEDAVHGIANEDAVYDIANDTVQGTLTRTLYRTSLMRTPYKASVM 2313 D H IANED+V+ IANE AVYDIANDTVQGTLTRTLY TSLMRTPYKASVM Sbjct: 257 TRTLHANVDTVHDIANEDSVYDIANEGAVYDIANDTVQGTLTRTLYTTSLMRTPYKASVM 316 Query: 2314 RTLYTTSLTRTPYKPSLTRTLYTTSLMRAPYKTSPMRALYTTLLMIPTRHANADTVHDIA 2373 RTLYTTSLTRTPYKPSLTRTLYTTSLM APYKTSPMRALYTTLLMIPTRHA D VHDIA Sbjct: 317 RTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALYTTLLMIPTRHAIVDAVHDIA 376 Query: 2374 NEDTV 2378 NED+V Sbjct: 377 NEDSV 381 Score = 359 bits (921), Expect = 2e-98 Identities = 201/377 (53%), Positives = 233/377 (61%), Gaps = 51/377 (13%) Query: 2040 NEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQ 2099 +ED H + NEDA+ I DA HGIANE A +GI NE+AAQ IA + Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEA-------------ADKGIANEDAAQGIANE 169 Query: 2100 DAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGV 2159 DAAHGI EDAAQG+ NEVAAQG+ANEDAA G+A E AAHG+ANEDAA G+ANE A G+ Sbjct: 170 DAAHGIASEDAAQGIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGI 229 Query: 2160 ANEDAVQGVANEVEVQGIAHK--------------DAIQGIANEDAAQGVANEVAAHGVA 2205 ANED+V +ANE + IA+ D + IANED+ +ANE A + +A Sbjct: 230 ANEDSVYDIANEDAIYDIANDTVQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYDIA 289 Query: 2206 NEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGI------- 2258 N+ + + + V + + + + + Sbjct: 290 NDTVQGTLTRTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKT 349 Query: 2259 -----------------ANEDAAHGIANEDAVHGIANEDAVYDIANDTVQGTLTRTLYRT 2301 A DA H IANED+V+ IANE AVYDIANDTVQGTLTRTLY T Sbjct: 350 SPMRALYTTLLMIPTRHAIVDAVHDIANEDSVYDIANEGAVYDIANDTVQGTLTRTLYTT 409 Query: 2302 SLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMRAPYKTSPMRALYTTLLMIPT 2361 SLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLM APYKTSPMRALYTTLLMIPT Sbjct: 410 SLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPT 469 Query: 2362 RHANADTVHDIANEDTV 2378 RHAN D VHDIANEDTV Sbjct: 470 RHANVDAVHDIANEDTV 486 Score = 273 bits (699), Expect = 1e-72 Identities = 166/318 (52%), Positives = 199/318 (62%), Gaps = 29/318 (9%) Query: 16 SSEESLVHKDRGDGERPVNVRVVQVAPLRHESTPYEDTVHDIANEDADAAHGITNEDAVQ 75 +SEESLVHKDRGDGERPVNV+VVQVAPLR ESTP+EDTVH+I NEDA +H ITNEDAV Sbjct: 89 ASEESLVHKDRGDGERPVNVKVVQVAPLRRESTPHEDTVHNITNEDA--SHDITNEDAVH 146 Query: 76 GVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANED 135 G+ANE A +G+ANEDAA G+ANE AAHG+A+EDAAQG+ANEVAAQG+ANEDA QG+A ED Sbjct: 147 GIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQGIANEDAAQGIAKED 206 Query: 136 AVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDI-----ANEDA 190 A G+ANEDA GIANEDA HGIANED+ IANEDA DIA + + AN D Sbjct: 207 AAHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIANDTVQGTLTRTLHANVDT 266 Query: 191 AQGISKEDAVQGIANEDAAQGIAKEDPVQGVANE----DPVQGVANEDAVQGVANEVEVQ 246 I+ ED+V IANE A IA D VQG + + +V + Sbjct: 267 VHDIANEDSVYDIANEGAVYDIA-NDTVQGTLTRTLYTTSLMRTPYKASVMRTLYTTSLT 325 Query: 247 GVAHEDAVQGIANEDA---AHGITNEVAA-----------HGIANEDAAQGIANEDAAQG 292 ++ ++ + A T+ + A H I DA IANED+ Sbjct: 326 RTPYKPSLTRTLYTTSLMMAPYKTSPMRALYTTLLMIPTRHAIV--DAVHDIANEDSVYD 383 Query: 293 IAHEDAVQGIANEDAVHG 310 IA+E AV IAN D V G Sbjct: 384 IANEGAVYDIAN-DTVQG 400 Score = 212 bits (540), Expect = 3e-54 Identities = 133/281 (47%), Positives = 161/281 (57%), Gaps = 16/281 (5%) Query: 1004 HKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQ 1063 H+D + I NEDA+H I NE A HGIANE A +GIANEDAAQGIANE AAHGI+ EDA Q Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQ 182 Query: 1064 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANED 1123 GIANE AAQGIANEDAAQGIA EDA GIANEDA HG+A E A HG+ANED V +ANED Sbjct: 183 GIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242 Query: 1124 AVQGVANEVEVQGV------AHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQG----- 1172 A+ +AN+ VQG A+ D V IANED+ + IANE A + IAN D QG Sbjct: 243 AIYDIANDT-VQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYDIAN-DTVQGTLTRT 300 Query: 1173 IANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANE-- 1230 + + ++ + K + A K R + Sbjct: 301 LYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALYTTLL 360 Query: 1231 VAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQG 1271 + A D IANED+ + +ANE A + I+ D VQG Sbjct: 361 MIPTRHAIVDAVHDIANEDSVYDIANEGAVYDIA-NDTVQG 400 Score = 204 bits (519), Expect = 8e-52 Identities = 130/282 (46%), Positives = 160/282 (56%), Gaps = 29/282 (10%) Query: 933 QDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQG 992 +D H+ITNEDA+ + NEDA HG+ANE A +G+ANE AAQG+ANEDA HG+A+EDA QG Sbjct: 124 EDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQG 183 Query: 993 VANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVA 1052 +ANEV QGIA++DA QGIA EDAAHGIANE AAHGIANEDA GIANED+ IANE A Sbjct: 184 IANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDA 243 Query: 1053 AHGISKEDAVQGI------ANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVA 1106 + I+ D VQG AN D IANED+ IA+E AV IAN D V G Sbjct: 244 IYDIA-NDTVQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYDIAN-DTVQGTLTRTL 301 Query: 1107 AHGVANEDP----VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDA----------- 1151 P V ++ + + + ++ + + Sbjct: 302 YTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALYTTLLM 361 Query: 1152 ---AHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQG 1190 H I + A H IANED+ IANE A IA+ D VQG Sbjct: 362 IPTRHAIVD--AVHDIANEDSVYDIANEGAVYDIAN-DTVQG 400 Score = 201 bits (511), Expect = 7e-51 Identities = 130/298 (43%), Positives = 161/298 (54%), Gaps = 20/298 (6%) Query: 1874 QGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQ 1933 + HED V I NEDA+H I NEDA GIANE A + IANEDAAQGI+ EDA GIA++ Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASE 178 Query: 1934 DAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGI 1993 DAAQGIA E A QGIANEDAAQGIA E AAHGIANEDAA GIANEDA GIA+ED+V I Sbjct: 179 DAAQGIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDI 238 Query: 1994 ANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAA 2053 ANEDA++ +AN D +G A D IANED+ + +ANE A Sbjct: 239 ANEDAIYDIAN----------DTVQGTLTRTLH---ANVDTVHDIANEDSVYDIANEGAV 285 Query: 2054 QAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGI--TKEDAA 2111 IA + T + ++ + + K + T A Sbjct: 286 YDIANDTVQGTLTRTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMA 345 Query: 2112 QGVTNEVAA--QGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQG 2167 T+ + A + H + + A H +ANED+ +ANE A +AN D VQG Sbjct: 346 PYKTSPMRALYTTLLMIPTRHAIVD--AVHDIANEDSVYDIANEGAVYDIAN-DTVQG 400 Score = 200 bits (509), Expect = 1e-50 Identities = 131/285 (45%), Positives = 158/285 (55%), Gaps = 24/285 (8%) Query: 1590 NEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQ 1649 +ED I DA+H I NE A H IAN+ A +GIAN+DAAQGIANE AAHGI+ EDA Q Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQ 182 Query: 1650 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANED 1709 GIANE AAQGIANEDAAQGIA EDA GIANEDA HG+A E A HG+ANED V +ANED Sbjct: 183 GIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242 Query: 1710 AVQGVANEVEVQGV------AHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHED 1763 A+ +AN+ VQG A+ D V IANED+ + I NE A + IAN D QG Sbjct: 243 AIYDIANDT-VQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYDIAN-DTVQG----T 296 Query: 1764 AVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGI-------ANEVAAQGIATE 1816 + + + + K + KP R + A + A Sbjct: 297 LTRTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALY 356 Query: 1817 DVADGIPNE----DAAHGVANEVAAHGISKEDAVQGIANEDAAQG 1857 IP DA H +ANE + + I+ E AV IAN D QG Sbjct: 357 TTLLMIPTRHAIVDAVHDIANEDSVYDIANEGAVYDIAN-DTVQG 400 Score = 197 bits (502), Expect = 8e-50 Identities = 127/287 (44%), Positives = 156/287 (54%), Gaps = 9/287 (3%) Query: 1346 NEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQ 1405 +ED I NEDA+ DI NEDA GI+ E A +GIANEDAAQGIA ED G+A+EDA Q Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQ 182 Query: 1406 GVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHED 1465 G+ANEV QG+A+EDA QGIA EDAAHGIANE AAHGIANEDA GIANED+ IA+ED Sbjct: 183 GIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242 Query: 1466 AVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIA 1525 A+ IAN D V G AN D H IA D+ IANE A IA + V + Sbjct: 243 AIYDIAN-DTVQGTLTRTLH---ANVDTVHDIANEDSVYDIANEGAVYDIANDTVQGTLT 298 Query: 1526 NEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALH 1585 + + + + + + T + + A AL+ Sbjct: 299 RTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTR--TLYTTSLMMAPYKTSPMRALY 356 Query: 1586 SVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQG 1632 + + AI DA H IANE + + IAN+ A IAN D QG Sbjct: 357 TTLLMIPTRHAIV--DAVHDIANEDSVYDIANEGAVYDIAN-DTVQG 400 Score = 197 bits (502), Expect = 8e-50 Identities = 125/276 (45%), Positives = 151/276 (54%), Gaps = 49/276 (17%) Query: 1843 EDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQG 1902 ED V I NEDA+ I ED + G+ANE +G+A+EDA QGIANEDAAHGIA+EDAAQG Sbjct: 124 EDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQG 183 Query: 1903 IANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVA 1962 IANE AAQ IANEDAAQGI+KEDA GIAN+DAA GIA EDAV GIANED+ IANE A Sbjct: 184 IANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDA 243 Query: 1963 AHGIANEDAAQGI------ANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIA---- 2012 + IAN D QG AN D IA+ED+V IANE AV+ +AN+ + Sbjct: 244 IYDIAN-DTVQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYDIANDTVQGTLTRTLY 302 Query: 2013 ---------------------------KPDAARGI-----------ANEVAAQGIATEDV 2034 KP R + + + A + Sbjct: 303 TTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALYTTLLMI 362 Query: 2035 ADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGI 2070 A DA H +ANED+ IA A + IAN+ + Sbjct: 363 PTRHAIVDAVHDIANEDSVYDIANEGAVYDIANDTV 398 Score = 195 bits (496), Expect = 4e-49 Identities = 126/287 (43%), Positives = 156/287 (54%), Gaps = 24/287 (8%) Query: 1292 NEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQ 1351 +ED I ED + NED + G+ANE +G+A+EDA QGIANEDAAHGIA+EDAAQ Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQ 182 Query: 1352 GIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEV 1411 GIANE AAQ IANEDAAQGI+KEDA GIANEDAA GIA ED V G+ANED+V +ANE Sbjct: 183 GIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242 Query: 1412 EVQGVAHEDAVQGI------ANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHED 1465 + +A+ D VQG AN D H IANE + + IANE A IAN D QG Sbjct: 243 AIYDIAN-DTVQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYDIAN-DTVQG----T 296 Query: 1466 AVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGI-----------ANEVATQG 1514 + + + K + KP R + + + Sbjct: 297 LTRTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALY 356 Query: 1515 IATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVV 1561 + A DA H +ANE + IANE AV+ +A D VQG + Sbjct: 357 TTLLMIPTRHAIVDAVHDIANEDSVYDIANEGAVYDIA-NDTVQGTL 402 Score = 194 bits (492), Expect = 1e-48 Identities = 124/286 (43%), Positives = 157/286 (54%), Gaps = 30/286 (10%) Query: 385 NEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAV 444 +ED +H + NEDA+ I DA HGIANE A GIANEDAAQGIANE AAHGI+ EDA Sbjct: 123 HEDTVHNIT-NEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAA 181 Query: 445 QGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKP 504 QGIANE AAQGIA+EDAAQGIA EDA GIANEDA HG+A E A HG+AN+D+ + IA Sbjct: 182 QGIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANE 241 Query: 505 DAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGI 564 DA IAN+ QG T + AN D VH +ANE + + +ANE A + IA + Sbjct: 242 DAIYDIANDTV-QGTLTRTLH---ANVDTVHDIANEDSVYDIANEGAVYDIANDTVQGTL 297 Query: 565 ANEVATQGIATEDVADGIANE----------------DAAHGVANEVAVHGVAIEDAVQG 608 + T + + + + +A + + A+ Sbjct: 298 TRTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALYT 357 Query: 609 V--------ANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVV 646 A DAVH +ANED+ IA E + +AN D VQG + Sbjct: 358 TLLMIPTRHAIVDAVHDIANEDSVYDIANEGAVYDIAN-DTVQGTL 402 Score = 193 bits (491), Expect = 1e-48 Identities = 110/211 (52%), Positives = 138/211 (65%), Gaps = 6/211 (2%) Query: 940 TNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEV 999 T E + + + ++D G + + + +ED VH + NEDA + NE V Sbjct: 86 TLEASEESLVHKDRGDGERPVNVKVVQVAPLRRESTPHEDTVHNITNEDASHDITNEDAV 145 Query: 1000 QGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKE 1059 GIA++ A +GIANEDAA GIANE AAHGIA+EDAAQGIANE AAQGIANE AA GI+KE Sbjct: 146 HGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQGIANEDAAQGIAKE 205 Query: 1060 DAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGV-----ANED 1114 DA GIANEDAA GIANEDA GIA+ED+V IANEDA++ +A + + AN D Sbjct: 206 DAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIANDTVQGTLTRTLHANVD 265 Query: 1115 PVQGVANEDAVQGVANEVEVQGVAHEDAVQG 1145 V +ANED+V +ANE V +A+ D VQG Sbjct: 266 TVHDIANEDSVYDIANEGAVYDIAN-DTVQG 295 Score = 192 bits (488), Expect = 3e-48 Identities = 133/384 (34%), Positives = 184/384 (47%), Gaps = 25/384 (6%) Query: 246 QGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANE 305 + HED V I NEDA+H ITNE A HGIANE A +GIANEDAAQGIA+EDA GIA+E Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASE 178 Query: 306 DAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGV 365 DA G+A EVAA G+ANEDAA IAK DAAHGIAN ED A GIANEDA HG+ Sbjct: 179 DAAQGIANEVAAQGIANEDAAQGIAKEDAAHGIAN---------EDAAHGIANEDAVHGI 229 Query: 366 AKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDA 425 A E + + +ANEDA+ + N D + G + A D H IANE + + IANE A Sbjct: 230 ANEDSVYDIANEDAIYDIAN-DTVQGTLTR----TLHANVDTVHDIANEDSVYDIANEGA 284 Query: 426 AQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAK 485 IAN+ +++ + + + + ++ + Sbjct: 285 VYDIANDTVQGTLTRTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTR--TLYTTSL 342 Query: 486 EVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHG 545 +A + + A + R + A IA ED IANE AV+ +AN+ Sbjct: 343 MMAPYKTSPMRALYTTLLMIPTRHAIVD-AVHDIANEDSVYDIANEGAVYDIANDTVQGT 401 Query: 546 VANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANE-------DAAHGVANEVAVH 598 + ++ + + + T + + A + + A++ Sbjct: 402 LTRTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMTAPYKTSPMRALY 461 Query: 599 GVAIEDAVQGVANEDAVHGVANED 622 + + AN DAVH +ANED Sbjct: 462 TTLLMIPTRH-ANVDAVHDIANED 484 Score = 192 bits (488), Expect = 3e-48 Identities = 123/280 (43%), Positives = 152/280 (54%), Gaps = 23/280 (8%) Query: 1166 NEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAR 1225 +ED I NEDA+ I +EDAV GIANE A G+A E AA G+ANEDAAH IA DAA+ Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQ 182 Query: 1226 GIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKED 1285 GIANEVAAQGIA ED A GIA EDAAHG+ANE AAHGI+ EDAV GIANED+ IA ED Sbjct: 183 GIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242 Query: 1286 AVQGIANEDAAQGI------AKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANED 1339 A+ IAN D QG A D V +ANED + +ANE V +A+ D VQG Sbjct: 243 AIYDIAN-DTVQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYDIAN-DTVQGTLTRT 300 Query: 1340 AAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGV- 1398 + + + + + K + + K P++ + Sbjct: 301 ----LYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALY 356 Query: 1399 ----------ANEDAVQGVANEVEVQGVAHEDAVQGIANE 1428 A DAV +ANE V +A+E AV IAN+ Sbjct: 357 TTLLMIPTRHAIVDAVHDIANEDSVYDIANEGAVYDIAND 396 Score = 191 bits (486), Expect = 6e-48 Identities = 106/175 (60%), Positives = 121/175 (69%), Gaps = 8/175 (4%) Query: 657 NEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQ 716 +ED I DA+H I NE A HGIANE A +GIANEDAAQGIANE AAHGI+ EDA Q Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQ 182 Query: 717 GIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEV 776 GIANE AAQGIA+EDA QGIA EDA HG+A E AAHG+ANED V G+ANED V +ANE Sbjct: 183 GIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242 Query: 777 EVQGIAHEDAVQGI------ANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQG 825 + IA+ D VQG AN D H IANE + + +ANE A +AN D QG Sbjct: 243 AIYDIAN-DTVQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYDIAN-DTVQG 295 Score = 191 bits (486), Expect = 6e-48 Identities = 122/284 (42%), Positives = 148/284 (52%), Gaps = 23/284 (8%) Query: 179 EDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQG 238 ED +I NEDA+ I+ EDAV GIANE A +GIA ED QG+ANED G+A+EDA QG Sbjct: 124 EDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQG 183 Query: 239 VANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDA 298 +ANEV QG+A+EDA QGIA EDAAHGI NE AAHGIANEDA GIANED+ IA+EDA Sbjct: 184 IANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDA 243 Query: 299 VQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIAN 358 + IAN D V G AN D H IA D+ + IANE A IA + V + Sbjct: 244 IYDIAN-DTVQGTLTRTLH---ANVDTVHDIANEDSVYDIANEGAVYDIANDTVQGTLTR 299 Query: 359 EDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKP------------- 405 + + V + + + P Sbjct: 300 TLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALYTTL 359 Query: 406 ---DAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQG 446 H I + A H IANED+ IANE A + I+ D VQG Sbjct: 360 LMIPTRHAIVD--AVHDIANEDSVYDIANEGAVYDIA-NDTVQG 400 Score = 191 bits (486), Expect = 6e-48 Identities = 118/280 (42%), Positives = 150/280 (53%), Gaps = 11/280 (3%) Query: 712 EDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQG 771 ED V I NEDA+ I +EDAV GIANE A G+A E AA G+ANED G+A+ED QG Sbjct: 124 EDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQG 183 Query: 772 VANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDA 831 +ANEV QGIA+EDA QGIA EDAAHGIANE AAHG+ANEDA G+ANED+ +ANEDA Sbjct: 184 IANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDA 243 Query: 832 VHGVANEDAAQGV------AKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPD 885 ++ +AN D QG A T H + NED+V + NE A++ +AN+ + + Sbjct: 244 IYDIAN-DTVQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYD-IANDTVQGTLTRTL 301 Query: 886 AAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSI--TNED 943 + V T + A K ++ T Sbjct: 302 YTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALYTTLLM 361 Query: 944 AAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHG 983 A DA H +ANED+ +ANE A +AN D V G Sbjct: 362 IPTRHAIVDAVHDIANEDSVYDIANEGAVYDIAN-DTVQG 400 Score = 191 bits (485), Expect = 7e-48 Identities = 106/176 (60%), Positives = 123/176 (69%), Gaps = 9/176 (5%) Query: 647 NEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAA 706 +ED +H + NEDA+ I DA HGIANE A GIANEDAAQGIANEDAA GIA+E AA Sbjct: 123 HEDTVHNIT-NEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAA 181 Query: 707 HGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANE 766 GI+ E A QGIANEDAAQGIA EDA GIANEDA HG+A E A HG+ANED V +ANE Sbjct: 182 QGIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANE 241 Query: 767 DVVQGVANEVEVQGI------AHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQG 816 D + +AN+ VQG A+ D V IANED+ + IANE A + +AN D QG Sbjct: 242 DAIYDIANDT-VQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYDIAN-DTVQG 295 Score = 190 bits (482), Expect = 2e-47 Identities = 122/281 (43%), Positives = 144/281 (51%), Gaps = 22/281 (7%) Query: 1865 QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKE 1924 + +E V + +EDA I NEDA HGIANE A +GIANEDAAQ IANEDAA GI+ E Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASE 178 Query: 1925 DAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGI 1984 DA QGIAN+ AAQGIA EDA QGIA EDAA GIANE AAHGIANEDA GIANED+ I Sbjct: 179 DAAQGIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDI 238 Query: 1985 AHEDAVQGIANEDAVHGV------ANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGI 2038 A+EDA+ IAN D V G AN D H IA D+ IANE A IA + V + Sbjct: 239 ANEDAIYDIAN-DTVQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYDIANDTVQGTL 297 Query: 2039 A-------------NEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQ 2085 + + KP + + Sbjct: 298 TRTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALYT 357 Query: 2086 GITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANE 2126 + AI DA H I ED+ + NE A +AN+ Sbjct: 358 TLLMIPTRHAIV--DAVHDIANEDSVYDIANEGAVYDIAND 396 Score = 189 bits (479), Expect = 4e-47 Identities = 117/282 (41%), Positives = 155/282 (54%), Gaps = 13/282 (4%) Query: 1324 QGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANE 1383 + HED V I NEDA+H I NEDA GIANE A + IANEDAAQGI+ EDA GIA+E Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASE 178 Query: 1384 DAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGI 1443 DAAQGIA E QG+ANEDA QG+A E G+A+EDA GIANEDA HGIANE + + I Sbjct: 179 DAAQGIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDI 238 Query: 1444 ANEDAAQGIANEDAAQGI------AHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAI 1497 ANEDA IAN D QG A+ D V IANED+V+ +A E A + +AN+ + Sbjct: 239 ANEDAIYDIAN-DTVQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYDIANDTVQGTL 297 Query: 1498 AKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAV 1557 + + + + + + + +A + + A+ Sbjct: 298 TRTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLM--MAPYKTSPMRAL 355 Query: 1558 QGVVKEV-TAHGVANEDAVQGVVNEDALHSVVANEDAAQAIA 1598 + + T H + DAV + NED+++ +ANE A IA Sbjct: 356 YTTLLMIPTRHAIV--DAVHDIANEDSVYD-IANEGAVYDIA 394 Score = 188 bits (478), Expect = 5e-47 Identities = 107/179 (59%), Positives = 120/179 (67%), Gaps = 8/179 (4%) Query: 1135 QGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANE 1194 + HED V I NEDA+H I NE A HGIANE A +GIANEDAAQGIA+EDA GIA+E Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASE 178 Query: 1195 DAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGV 1254 DA G+A EVAA G+ANEDAA IAK DAA GIANE AA GIA ED GIANED+ + + Sbjct: 179 DAAQGIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDI 238 Query: 1255 ANEVAAHGISKEDAVQGI------ANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQG 1307 ANE A + I+ D VQG AN D IA ED+V IANE A IA D VQG Sbjct: 239 ANEDAIYDIA-NDTVQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYDIA-NDTVQG 295 Score = 187 bits (475), Expect = 1e-46 Identities = 113/279 (40%), Positives = 152/279 (54%), Gaps = 12/279 (4%) Query: 219 QGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANE 278 + +ED V + NEDA + NE V G+A+E A +GIANEDAA GI NE AAHGIA+E Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASE 178 Query: 279 DAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGI 338 DAAQGIANE AAQGIA+EDA QGIA EDA HG+A E AAHG+ANEDA H IA D+ + I Sbjct: 179 DAAQGIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDI 238 Query: 339 ANEVATQGIATEDVADGI-----ANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVV 393 ANE A IA + V + AN D H +A E + + +ANE AV + N D + G + Sbjct: 239 ANEDAIYDIANDTVQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYDIAN-DTVQGTL 297 Query: 394 ANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGIS----KEDAVQGIAN 449 ++ + + + + + + + K ++ + Sbjct: 298 TRTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALYT 357 Query: 450 EDAAQGIAHE--DAAQGIAHEDAVQGIANEDAVHGVAKE 486 H DA IA+ED+V IANE AV+ +A + Sbjct: 358 TLLMIPTRHAIVDAVHDIANEDSVYDIANEGAVYDIAND 396 Score = 186 bits (473), Expect = 2e-46 Identities = 107/183 (58%), Positives = 122/183 (66%), Gaps = 6/183 (3%) Query: 607 QGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAK 666 + +ED VH + NEDA+ I E HG+ANE A +G+ NEDA G +ANEDAA IA Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQG-IANEDAAHGIAS 177 Query: 667 PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG 726 DAA GIANEVAA GIANEDAAQGIA EDAA GIANE AAHGI+ EDAV GIANED+ Sbjct: 178 EDAAQGIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYD 237 Query: 727 IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDA 786 IA+EDA+ IAN D V G AN D V +ANED V +ANE V IA+ D Sbjct: 238 IANEDAIYDIAN-DTVQGTLTRTLH---ANVDTVHDIANEDSVYDIANEGAVYDIAN-DT 292 Query: 787 VQG 789 VQG Sbjct: 293 VQG 295 Score = 185 bits (470), Expect = 4e-46 Identities = 123/288 (42%), Positives = 151/288 (52%), Gaps = 22/288 (7%) Query: 1721 QGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKE 1780 + HED V I NEDA+H ITNE A HGIANE A +GIA+EDA QGIANEDA H +A E Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASE 178 Query: 1781 VAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGI 1840 AA G+ANE AA IA DAA+GIA E AA GIA ED A GI NEDA HG+ANE + + I Sbjct: 179 DAAQGIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDI 238 Query: 1841 SKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAA 1900 + EDA+ IAN D QG AN V +A+ED+V IANE A + IAN D Sbjct: 239 ANEDAIYDIAN-DTVQGTLTRTL---HANVDTVHDIANEDSVYDIANEGAVYDIAN-DTV 293 Query: 1901 QGIANE--------------DAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQ 1946 QG + + + K + + K ++ Sbjct: 294 QGTLTRTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMR 353 Query: 1947 GIANEDAAQGIANEV--AAHGIANEDAAQGIANEDAAQGIAHEDAVQG 1992 + + + A H IANED+ IANE A IA+ D VQG Sbjct: 354 ALYTTLLMIPTRHAIVDAVHDIANEDSVYDIANEGAVYDIAN-DTVQG 400 Score = 185 bits (470), Expect = 4e-46 Identities = 120/285 (42%), Positives = 153/285 (53%), Gaps = 23/285 (8%) Query: 449 NEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAAR 508 +ED I +EDA+ I +EDAV GIANE A G+A E AA G+AN+DAAH IA DAA+ Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQ 182 Query: 509 GIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEV 568 GIANEVAAQGIA ED A GIA EDA HG+ANE AAHG+ANEDA H IA D+ + IANE Sbjct: 183 GIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242 Query: 569 ATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIA 628 A IA + V + H AN VH +A ED+V +ANE AV+ +AN+ + Sbjct: 243 AIYDIANDTVQGTLTR--TLH--ANVDTVHDIANEDSVYDIANEGAVYDIANDTVQGTLT 298 Query: 629 KEVTAHGVANEDAVQGVVN------------EDALHGVVANEDAAQAIAKPDAAHGIANE 676 + + + V+ + +L + A K + Sbjct: 299 RTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALYTT 358 Query: 677 V----AAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQG 717 + H I DA IANED+ IANE A + I+ D VQG Sbjct: 359 LLMIPTRHAIV--DAVHDIANEDSVYDIANEGAVYDIA-NDTVQG 400 Score = 185 bits (469), Expect = 5e-46 Identities = 128/318 (40%), Positives = 159/318 (50%), Gaps = 47/318 (14%) Query: 1176 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAA---HGVANEDAAHAIAKPDAARGIANEVA 1232 E + + + H+D G E V+ +VA +ED H I DA+ I NE A Sbjct: 88 EASEESLVHKDRGDG---ERPVNVKVVQVAPLRRESTPHEDTVHNITNEDASHDITNEDA 144 Query: 1233 AQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIAN 1292 GIA E GIANEDAA G+ANE AAHGI+ EDA QGIANE AAQGIA EDA QGIA Sbjct: 145 VHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQGIANEDAAQGIAK 204 Query: 1293 EDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANE-------------- 1338 EDAA GIA ED G+ANED + G+ANE V +A+EDA+ IAN+ Sbjct: 205 EDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIANDTVQGTLTRTLHANV 264 Query: 1339 DAAHGIANEDAAQGIANEDAAQDIANEDAAQGI--------------SKEDAVQGIANED 1384 D H IANED+ IANE A DIAN D QG K ++ + Sbjct: 265 DTVHDIANEDSVYDIANEGAVYDIAN-DTVQGTLTRTLYTTSLMRTPYKASVMRTLYTTS 323 Query: 1385 AAQGIAKEDPVQGVANEDAVQGVANEVEVQGV-----------AHEDAVQGIANEDAAHG 1433 + K + + + ++ + A DAV IANED+ + Sbjct: 324 LTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALYTTLLMIPTRHAIVDAVHDIANEDSVYD 383 Query: 1434 IANEVAAHGIANEDAAQG 1451 IANE A + IAN D QG Sbjct: 384 IANEGAVYDIAN-DTVQG 400 Score = 185 bits (469), Expect = 5e-46 Identities = 116/289 (40%), Positives = 148/289 (51%), Gaps = 27/289 (9%) Query: 693 NEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAH 752 +ED I NE A+H I+ EDAV GIANE A +GIA+EDA QGIANEDA AH Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDA---------AH 173 Query: 753 GVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANED 812 G+A+ED QG+ANE QG+ANE QGIA EDA GIANEDAAHGIANE A HG+ANED Sbjct: 174 GIASEDAAQGIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANED 233 Query: 813 AAQGVANEDAAQGVANE--------------DAVHGVANEDAAQGVAKEVTAHGVTNEDA 858 + +ANEDA +AN+ D VH +ANED+ +A E + + N D Sbjct: 234 SVYDIANEDAIYDIANDTVQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYDIAN-DT 292 Query: 859 VQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAA 918 VQG + + ++ + + + T + Sbjct: 293 VQGTLTRTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPM 352 Query: 919 HGI--TKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQG 965 + T A DA H I NED+ +ANE A + +AN D QG Sbjct: 353 RALYTTLLMIPTRHAIVDAVHDIANEDSVYDIANEGAVYDIAN-DTVQG 400 Score = 184 bits (466), Expect = 1e-45 Identities = 124/329 (37%), Positives = 167/329 (50%), Gaps = 32/329 (9%) Query: 450 EDAAQGIAHEDAAQGIAHEDA----VQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPD 505 E + + + H+D G + V + E H E H + N+DA+H I D Sbjct: 88 EASEESLVHKDRGDGERPVNVKVVQVAPLRRESTPH----EDTVHNITNEDASHDITNED 143 Query: 506 AARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIA 565 A GIANE A +GIA ED A GIANEDA HG+A+E AA G+ANE AA GIA Sbjct: 144 AVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQ---------GIA 194 Query: 566 NEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQ 625 NE A QGIA ED A GIANEDAAHG+ANE AVHG+A ED+V +ANEDA++ +AN D Q Sbjct: 195 NEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIAN-DTVQ 253 Query: 626 GI------AKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAA 679 G A T H +ANED+V + NE A++ +AN+ + + + Sbjct: 254 GTLTRTLHANVDTVHDIANEDSVYDIANEGAVYD-IANDTVQGTLTRTLYTTSLMRTPYK 312 Query: 680 HGIANEDAAQGIANEDAAQGIANEVAAHGIS----KEDAVQGIANEDAAQGIAHE--DAV 733 + + + + + K ++ + H DAV Sbjct: 313 ASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALYTTLLMIPTRHAIVDAV 372 Query: 734 QGIANEDAVHGVAKEVAAHGVANEDPVQG 762 IANED+V+ +A E A + +AN D VQG Sbjct: 373 HDIANEDSVYDIANEGAVYDIAN-DTVQG 400 Score = 182 bits (461), Expect = 4e-45 Identities = 116/283 (40%), Positives = 147/283 (51%), Gaps = 23/283 (8%) Query: 1770 NEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAH 1829 +ED VH++ E A+H + NEDA H IA A +GIANE AAQGIA ED A GI +EDAA Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQ 182 Query: 1830 GVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANED 1889 G+ANEVAA GI+ EDA QGIA EDAA GIA ED G+ANE V G+A+ED+V IANED Sbjct: 183 GIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242 Query: 1890 AAHGIANEDAAQGI------ANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKED 1943 A + IAN D QG AN D DIANED+ I+ E AV IAN + + Sbjct: 243 AIYDIAN-DTVQGTLTRTLHANVDTVHDIANEDSVYDIANEGAVYDIANDTVQGTLTRTL 301 Query: 1944 AVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIA----HEDAVQGI------ 1993 + + + + + + ++ + Sbjct: 302 YTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALYTTLLM 361 Query: 1994 -----ANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIAT 2031 A DAVH +ANED+ + IA A IAN+ QG T Sbjct: 362 IPTRHAIVDAVHDIANEDSVYDIANEGAVYDIAND-TVQGTLT 403 Score = 175 bits (443), Expect = 5e-43 Identities = 101/178 (56%), Positives = 118/178 (66%), Gaps = 6/178 (3%) Query: 1554 EDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAH 1613 ED V + E +H + NEDAV G+ NE A +ANEDAAQ IA DAAHGIA+E AA Sbjct: 124 EDTVHNITNEDASHDITNEDAVHGIANE-AADKGIANEDAAQGIANEDAAHGIASEDAAQ 182 Query: 1614 SIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHED 1673 IAN+ AAQGIAN+DAAQGIA E AAHGI+ EDA GIANEDA GIANED+ IA+ED Sbjct: 183 GIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242 Query: 1674 AVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQG 1731 A+ IAN D V G AN D V +ANED+V +ANE V +A+ D VQG Sbjct: 243 AIYDIAN-DTVQGTLTRTLH---ANVDTVHDIANEDSVYDIANEGAVYDIAN-DTVQG 295 Score = 174 bits (442), Expect = 7e-43 Identities = 116/308 (37%), Positives = 153/308 (49%), Gaps = 48/308 (15%) Query: 761 QGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANE 820 + +ED V + NE I +EDAV GIANE A GIANE AA G+ANEDAA G+A+E Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASE 178 Query: 821 DAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQA 880 DAAQG+ANE A G+ANEDAAQG+AKE AHG+ NEDA G+ NE+A+HG +ANED+ Sbjct: 179 DAAQGIANEVAAQGIANEDAAQGIAKEDAAHGIANEDAAHGIANEDAVHG-IANEDSVYD 237 Query: 881 IAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSIT 940 IA DA + IAN+ V QG T + A D H I Sbjct: 238 IANEDAIYDIANDTV------QGTLTRTLH--------------------ANVDTVHDIA 271 Query: 941 NEDAAQGVANEDAAHGVANEDAAQGVAN-------------EVAAQGVANEDAVHGVANE 987 NED+ +ANE A + +AN D QG + + ++ + Sbjct: 272 NEDSVYDIANEGAVYDIAN-DTVQGTLTRTLYTTSLMRTPYKASVMRTLYTTSLTRTPYK 330 Query: 988 DAVQGVANEVEVQGIAHKDA-----IQGIANEDAAHGIANEVAAHGIANEDAAQGIANED 1042 ++ + +K + + H I + A H IANED+ IANE Sbjct: 331 PSLTRTLYTTSLMMAPYKTSPMRALYTTLLMIPTRHAIVD--AVHDIANEDSVYDIANEG 388 Query: 1043 AAQGIANE 1050 A IAN+ Sbjct: 389 AVYDIAND 396 Score = 170 bits (431), Expect = 1e-41 Identities = 125/326 (38%), Positives = 157/326 (48%), Gaps = 35/326 (10%) Query: 1455 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQG 1514 E + + + H+D G E V+ +VA + E H D I NE A+ Sbjct: 88 EASEESLVHKDRGDG---ERPVNVKVVQVAP--LRRESTPHE----DTVHNITNEDASHD 138 Query: 1515 IATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDA 1574 I ED GIANE A G+ANE AAQGIANE A HG+A EDA QG+ EV A G+ANEDA Sbjct: 139 ITNEDAVHGIANEAADKGIANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQGIANEDA 198 Query: 1575 VQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGI- 1633 QG+ EDA H +ANEDAA IA DA HGIANE + + IAN+DA IAN D QG Sbjct: 199 AQGIAKEDAAHG-IANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIAN-DTVQGTL 256 Query: 1634 -----ANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIA--------------HEDA 1674 AN H I+ ED+V IANE A IAN D QG Sbjct: 257 TRTLHANVDTVHDIANEDSVYDIANEGAVYDIAN-DTVQGTLTRTLYTTSLMRTPYKASV 315 Query: 1675 VQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHE--DAVQGI 1732 ++ + K + + ++ + + + H DAV I Sbjct: 316 MRTLYTTSLTRTPYKPSLTRTLYTTSLMMAPYKTSPMRALYTTLLMIPTRHAIVDAVHDI 375 Query: 1733 ANEDAAHGITNEVAAHGIANEDAAQG 1758 ANED+ + I NE A + IAN D QG Sbjct: 376 ANEDSVYDIANEGAVYDIAN-DTVQG 400 Score = 32.7 bits (73), Expect = 4.4 Identities = 15/34 (44%), Positives = 21/34 (61%), Gaps = 1/34 (2%) Query: 830 DAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVV 863 DAVH +ANED+ +A E + + N D VQG + Sbjct: 370 DAVHDIANEDSVYDIANEGAVYDIAN-DTVQGTL 402 >gi|239746623 PREDICTED: hypothetical protein [Homo sapiens] Length = 445 Score = 359 bits (921), Expect = 2e-98 Identities = 201/341 (58%), Positives = 224/341 (65%), Gaps = 62/341 (18%) Query: 2081 EDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHG 2140 ED V ITNE DA+H IT EDA G+ NE AAQG+ANEDAA G+ANE AAHG Sbjct: 124 EDTVHNITNE---------DASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHG 174 Query: 2141 VANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVA 2200 +A+EDAAQG+ANEVAAQG+ANEDA QG+ANE DA+ GIANEDAA G+ANE A Sbjct: 175 IASEDAAQGIANEVAAQGIANEDAAQGIANE---------DAVHGIANEDAAHGIANEDA 225 Query: 2201 AHGVANEDAAQGVANEVAAQGVANEDAAQGVANEV--------------AVHGVANEDAA 2246 HG+ANED+ +ANE A +AN D QG + + + Sbjct: 226 VHGIANEDSVYDIANEDAIYDIAN-DTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLT 284 Query: 2247 RHMAKEDAAQGI-----------------------------ANEDAAHGIANEDAVHGIA 2277 R + K + + AN D H IANED+V+ IA Sbjct: 285 RTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIA 344 Query: 2278 NEDAVYDIANDTVQGTLTRTLYRTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTT 2337 NE AVYDIANDTVQGTLTRTLY TSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTT Sbjct: 345 NEGAVYDIANDTVQGTLTRTLYTTSLMRTPYKASVMRTLYTTSLTRTPYKPSLTRTLYTT 404 Query: 2338 SLMRAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDTV 2378 SLM APYKTSPMRALYTTLLMIPTRHAN D VHDIANEDTV Sbjct: 405 SLMTAPYKTSPMRALYTTLLMIPTRHANVDAVHDIANEDTV 445 Score = 347 bits (891), Expect = 6e-95 Identities = 180/236 (76%), Positives = 196/236 (83%), Gaps = 18/236 (7%) Query: 2143 NEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAH 2202 +ED + NE A+ + NEDAV G+ANE A QGIANEDAAQG+ANE AAH Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEA---------AAQGIANEDAAQGIANEDAAH 173 Query: 2203 GVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANED 2262 G+A+EDAAQG+ANEVAAQG+ANEDAAQG+ANE AVHG+AN EDAA GIANED Sbjct: 174 GIASEDAAQGIANEVAAQGIANEDAAQGIANEDAVHGIAN---------EDAAHGIANED 224 Query: 2263 AAHGIANEDAVHGIANEDAVYDIANDTVQGTLTRTLYRTSLMRTPYKASVMRTLYTTSLT 2322 A HGIANED+V+ IANEDA+YDIANDTVQGTLTR LY TSLMRTPYKASVMRTLY TSLT Sbjct: 225 AVHGIANEDSVYDIANEDAIYDIANDTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLT 284 Query: 2323 RTPYKPSLTRTLYTTSLMRAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDTV 2378 RT YKPSLTRTLYTTSLM APYKTSPMRALYTTLLMIPTRHANADTVHDIANED+V Sbjct: 285 RTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSV 340 Score = 270 bits (691), Expect = 1e-71 Identities = 151/274 (55%), Positives = 179/274 (65%), Gaps = 36/274 (13%) Query: 16 SSEESLVHKDRGDGERPVNVRVVQVAPLRHESTPYEDTVHDIANEDADAAHGITNEDAVQ 75 +SEESLVHKDRGDGERPVNVRVVQVAPLR ESTP+EDTVH+I NEDA +H ITNEDAV Sbjct: 89 ASEESLVHKDRGDGERPVNVRVVQVAPLRRESTPHEDTVHNITNEDA--SHDITNEDAVH 146 Query: 76 GVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANED 135 G+ANE AAQG+ANEDAA G+ANE AAHG+A+EDAAQG+ANEVAAQG+ANEDA QG+ANED Sbjct: 147 GIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQGIANEDAAQGIANED 206 Query: 136 AVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIA------------------ 177 AV G+ANEDA GIANEDA HGIANED+ IANEDA DIA Sbjct: 207 AVHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIANDTVQGTLTRMLYTTSLM 266 Query: 178 ----KEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGV-----------A 222 K + + + + K + + K P++ + A Sbjct: 267 RTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHA 326 Query: 223 NEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQG 256 N D V +ANED+V +ANE V +A+ D VQG Sbjct: 327 NADTVHDIANEDSVYDIANEGAVYDIAN-DTVQG 359 Score = 191 bits (485), Expect = 7e-48 Identities = 97/133 (72%), Positives = 108/133 (81%), Gaps = 1/133 (0%) Query: 1004 HKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQ 1063 H+D + I NEDA+H I NE A HGIANE AAQGIANEDAAQGIANE AAHGI+ EDA Q Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQ 182 Query: 1064 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANED 1123 GIANE AAQGIANEDAAQGIA+EDAV GIANEDA HG+A E A HG+ANED V +ANED Sbjct: 183 GIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242 Query: 1124 AVQGVANEVEVQG 1136 A+ +AN+ VQG Sbjct: 243 AIYDIANDT-VQG 254 Score = 191 bits (484), Expect = 1e-47 Identities = 121/254 (47%), Positives = 141/254 (55%), Gaps = 27/254 (10%) Query: 1324 QGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANE 1383 + HED V I NEDA+H I NEDA GIANE AAQ IANEDAAQGI+ EDA GIA+E Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASE 178 Query: 1384 DAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGI 1443 DAAQGIA E QG+ANEDA QG+ANE DAV GIANEDAAHGIANE A HGI Sbjct: 179 DAAQGIANEVAAQGIANEDAAQGIANE---------DAVHGIANEDAAHGIANEDAVHGI 229 Query: 1444 ANEDAAQGIANEDAAQGIAHEDAVQG-----IANEDAVHGVAKEVAAHGVANEDAAHAIA 1498 ANED+ IANEDA IA+ D VQG + + K + + Sbjct: 230 ANEDSVYDIANEDAIYDIAN-DTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLY 288 Query: 1499 KPDAARGI-ANEVATQGIATED----------VADGIANEDAAHGVANEVAAQGIANEVA 1547 KP R + + T T + AN D H +ANE + IANE A Sbjct: 289 KPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGA 348 Query: 1548 VHGVAIEDAVQGVV 1561 V+ +A D VQG + Sbjct: 349 VYDIA-NDTVQGTL 361 Score = 189 bits (481), Expect = 2e-47 Identities = 112/239 (46%), Positives = 133/239 (55%), Gaps = 42/239 (17%) Query: 1874 QGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQ 1933 + HED V I NEDA+H I NEDA GIANE AAQ IANEDAAQGI+ EDA GIA++ Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASE 178 Query: 1934 DAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGI 1993 DAAQGIA E A QGIANEDAAQGIANE A HGIANEDAA GIANEDA GIA+ED+V I Sbjct: 179 DAAQGIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDI 238 Query: 1994 ANEDAVHGVANE-------------------------------DAAHAIAKPDAARGI-- 2020 ANEDA++ +AN+ + KP R + Sbjct: 239 ANEDAIYDIANDTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYT 298 Query: 2021 ---------ANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGI 2070 + + A + AN D H +ANED+ IA A + IAN+ + Sbjct: 299 TSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIANDTV 357 Score = 189 bits (480), Expect = 3e-47 Identities = 111/242 (45%), Positives = 143/242 (59%), Gaps = 8/242 (3%) Query: 933 QDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQG 992 +D H+ITNEDA+ + NEDA HG+ANE AAQG+ANE AAQG+ANEDA HG+A+EDA QG Sbjct: 124 EDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQG 183 Query: 993 VANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVA 1052 +ANEV QGIA++DA QGIANEDA HGIANE AAHGIANEDA GIANED+ IANE A Sbjct: 184 IANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDA 243 Query: 1053 AHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVAN 1112 + I+ D VQG + + + ++ + + K + Sbjct: 244 IYDIA-NDTVQG----TLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYT 298 Query: 1113 EDPVQGVANEDAVQGVANEVEVQGVAH--EDAVQGIANEDAAHGIANEVAAHGIANEDAA 1170 + ++ + + + H D V IANED+ + IANE A + IAN D Sbjct: 299 TSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIAN-DTV 357 Query: 1171 QG 1172 QG Sbjct: 358 QG 359 Score = 179 bits (455), Expect = 2e-44 Identities = 110/238 (46%), Positives = 133/238 (55%), Gaps = 18/238 (7%) Query: 1059 EDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQG 1118 ED V I NEDA+ I NEDA GIA+E A QGIANEDA G+A E AAHG+A+ED QG Sbjct: 124 EDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQG 183 Query: 1119 VANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDA 1178 +ANE A QG+ANE QG+A+EDAV GIANEDAAHGIANE A HGIANED+ IANEDA Sbjct: 184 IANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDA 243 Query: 1179 AQGIAHEDAVQG-----IANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGI------ 1227 IA+ D VQG + + K + + KP R + Sbjct: 244 IYDIAN-DTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSLM 302 Query: 1228 -----ANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQG 1280 + + A + AN D H +ANE + + I+ E AV IAN D QG Sbjct: 303 TAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIAN-DTVQG 359 Score = 179 bits (453), Expect = 4e-44 Identities = 114/246 (46%), Positives = 140/246 (56%), Gaps = 13/246 (5%) Query: 385 NEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAV 444 +ED +H + NEDA+ I DA HGIANE AA GIANEDAAQGIANE AAHGI+ EDA Sbjct: 123 HEDTVHNIT-NEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAA 181 Query: 445 QGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKP 504 QGIANE AAQGIA+EDAAQGIA+EDAV GIANEDA HG+A E A HG+AN+D+ + IA Sbjct: 182 QGIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANE 241 Query: 505 DAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGI 564 DA IAN+ QG T + + + + KP + Sbjct: 242 DAIYDIAND-TVQGTLTR----MLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTL 296 Query: 565 -ANEVATQGIATEDVA---DGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVAN 620 + T T + + H AN VH +A ED+V +ANE AV+ +AN Sbjct: 297 YTTSLMTAPYKTSPMRALYTTLLMIPTRH--ANADTVHDIANEDSVYDIANEGAVYDIAN 354 Query: 621 EDAAQG 626 D QG Sbjct: 355 -DTVQG 359 Score = 179 bits (453), Expect = 4e-44 Identities = 109/238 (45%), Positives = 133/238 (55%), Gaps = 27/238 (11%) Query: 1239 EDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQG 1298 ED I NEDA+H + NE A HGI+ E A QGIANEDAAQGIA EDA GIA+EDAAQG Sbjct: 124 EDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQG 183 Query: 1299 IAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDA 1358 IA E QG+ANED QG+ANE V G+A+EDA GIANEDA HGIANED+ IANEDA Sbjct: 184 IANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDA 243 Query: 1359 AQDIANEDAAQGI--------------SKEDAVQGIANEDAAQGIAKEDPVQGVANEDAV 1404 DIAN D QG K ++ + + + K + + + Sbjct: 244 IYDIAN-DTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSLM 302 Query: 1405 QGVANEVEVQGV-----------AHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQG 1451 ++ + A+ D V IANED+ + IANE A + IAN D QG Sbjct: 303 TAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIAN-DTVQG 359 Score = 179 bits (453), Expect = 4e-44 Identities = 105/233 (45%), Positives = 128/233 (54%), Gaps = 26/233 (11%) Query: 179 EDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQG 238 ED +I NEDA+ I+ EDAV GIANE AAQGIA ED QG+ANED G+A+EDA QG Sbjct: 124 EDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQG 183 Query: 239 VANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDA 298 +ANEV QG+A+EDA QGIANEDA HGI NE AAHGIANEDA GIANED+ IA+EDA Sbjct: 184 IANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDA 243 Query: 299 VQGIANEDAVHGVA--------------KEVAAHGVANEDAAHAIAKPDAAHGI-ANEVA 343 + IAN D V G K + + KP + + Sbjct: 244 IYDIAN-DTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSLM 302 Query: 344 TQGIATED----------VADGIANEDAAHGVAKEVTAHGVANEDAVQGVVNE 386 T T + AN D H +A E + + +ANE AV + N+ Sbjct: 303 TAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIAND 355 Score = 178 bits (452), Expect = 5e-44 Identities = 92/133 (69%), Positives = 104/133 (78%), Gaps = 1/133 (0%) Query: 1590 NEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQ 1649 +ED I DA+H I NE A H IAN+ AAQGIAN+DAAQGIANE AAHGI+ EDA Q Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQ 182 Query: 1650 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANED 1709 GIANE AAQGIANEDAAQGIA+EDAV GIANEDA HG+A E A HG+ANED V +ANED Sbjct: 183 GIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242 Query: 1710 AVQGVANEVEVQG 1722 A+ +AN+ VQG Sbjct: 243 AIYDIANDT-VQG 254 Score = 177 bits (448), Expect = 1e-43 Identities = 93/133 (69%), Positives = 103/133 (77%), Gaps = 1/133 (0%) Query: 657 NEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQ 716 +ED I DA+H I NE A HGIANE AAQGIANEDAAQGIANE AAHGI+ EDA Q Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQ 182 Query: 717 GIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEV 776 GIANE AAQGIA+EDA QGIANEDAVHG+A E AAHG+ANED V G+ANED V +ANE Sbjct: 183 GIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242 Query: 777 EVQGIAHEDAVQG 789 + IA+ D VQG Sbjct: 243 AIYDIAN-DTVQG 254 Score = 177 bits (448), Expect = 1e-43 Identities = 104/254 (40%), Positives = 135/254 (53%), Gaps = 18/254 (7%) Query: 712 EDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQG 771 ED V I NEDA+ I +EDAV GIANE A G+A E AA G+ANED G+A+ED QG Sbjct: 124 EDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQG 183 Query: 772 VANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDA 831 +ANEV QGIA+EDA QGIANEDA HGIANE AAHG+ANEDA G+ANED+ +ANEDA Sbjct: 184 IANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDA 243 Query: 832 VHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIA 891 ++ +AN D QG T + ++ + ++ + + + KP + Sbjct: 244 IYDIAN-DTVQG-----TLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLY 297 Query: 892 NEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANE 951 + + H A D H I NED+ +ANE Sbjct: 298 TTSLMTAPYKTSPMRALYTTLLMIPTRH-----------ANADTVHDIANEDSVYDIANE 346 Query: 952 DAAHGVANEDAAQG 965 A + +AN D QG Sbjct: 347 GAVYDIAN-DTVQG 359 Score = 176 bits (446), Expect = 2e-43 Identities = 108/243 (44%), Positives = 130/243 (53%), Gaps = 44/243 (18%) Query: 246 QGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANE 305 + HED V I NEDA+H ITNE A HGIANE AAQGIANEDAAQGIA+EDA GIA+E Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASE 178 Query: 306 DAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGV 365 DA G+A EVAA G+ANEDAA IA DA HGIANE A GIA ED GIANED+ + + Sbjct: 179 DAAQGIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDI 238 Query: 366 AKEVTAHGVANEDAVQGVVN-------------EDALHGVVANEDAAQAIAKPDAAHGI- 411 A E + +AN D VQG + + ++ + + + KP + Sbjct: 239 ANEDAIYDIAN-DTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLY 297 Query: 412 ----------------------------ANEVAAHGIANEDAAQGIANEVAAHGISKEDA 443 AN H IANED+ IANE A + I+ D Sbjct: 298 TTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIA-NDT 356 Query: 444 VQG 446 VQG Sbjct: 357 VQG 359 Score = 176 bits (446), Expect = 2e-43 Identities = 104/237 (43%), Positives = 130/237 (54%), Gaps = 16/237 (6%) Query: 1104 EVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHG 1163 E H + NED + NEDAV G+ANE QG+A+EDA QGIANEDAAHGIA+E AA G Sbjct: 124 EDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQG 183 Query: 1164 IANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDA 1223 IANE AAQGIANEDAAQGIA+EDAV GIANEDA HG+A E A HG+ANED+ + IA DA Sbjct: 184 IANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDA 243 Query: 1224 ARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGIS----KEDAVQGIANEDAAQ 1279 IAN+ + + V + ++ K + + Sbjct: 244 IYDIANDTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSLMT 303 Query: 1280 GIAKEDAVQGI-----------ANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQG 1325 K ++ + AN D IA ED V +ANE + +AN+ VQG Sbjct: 304 APYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIANDT-VQG 359 Score = 176 bits (445), Expect = 3e-43 Identities = 108/273 (39%), Positives = 140/273 (51%), Gaps = 25/273 (9%) Query: 1609 EVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQG 1668 E + S+ +KD G + + ED V I NEDA+ I NEDA G Sbjct: 88 EASEESLVHKDRGDGERPVNVRVVQVAPLRRESTPHEDTVHNITNEDASHDITNEDAVHG 147 Query: 1669 IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDA 1728 IA+E A QGIANEDA G+A E AAHG+A+ED QG+ANE A QG+ANE QG+A+EDA Sbjct: 148 IANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQGIANEDAAQGIANEDA 207 Query: 1729 VQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVAN 1788 V GIANEDAAHGI NE A HGIANED+ IA+EDA+ IAN+ ++ + + + Sbjct: 208 VHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIANDTVQGTLTRMLYTTSLMR 267 Query: 1789 -------------EDAAHAIAKPDAARGI-----------ANEVAAQGIATEDVADGIPN 1824 + KP R + + + A + N Sbjct: 268 TPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHAN 327 Query: 1825 EDAAHGVANEVAAHGISKEDAVQGIANEDAAQG 1857 D H +ANE + + I+ E AV IAN D QG Sbjct: 328 ADTVHDIANEDSVYDIANEGAVYDIAN-DTVQG 359 Score = 176 bits (445), Expect = 3e-43 Identities = 113/256 (44%), Positives = 134/256 (52%), Gaps = 35/256 (13%) Query: 1721 QGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKE 1780 + HED V I NEDA+H ITNE A HGIANE AA QGIANEDA Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAAA---------QGIANEDA------- 162 Query: 1781 VAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGI 1840 A G+ANEDAAH IA DAA+GIANEVAAQGIA ED A GI NEDA HG+ANE AAHGI Sbjct: 163 --AQGIANEDAAHGIASEDAAQGIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGI 220 Query: 1841 SKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHE-----DAVQGIANEDAAHGIA 1895 + EDAV GIANED+ IA ED I +AN+ VQG ++ + Sbjct: 221 ANEDAVHGIANEDSVYDIANEDAIYDIANDT-VQGTLTRMLYTTSLMRTPYKASVMRTLY 279 Query: 1896 NEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGI-----------ANQDAAQGIAKEDA 1944 + + + + K ++ + AN D IA ED+ Sbjct: 280 MTSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDS 339 Query: 1945 VQGIANEDAAQGIANE 1960 V IANE A IAN+ Sbjct: 340 VYDIANEGAVYDIAND 355 Score = 175 bits (444), Expect = 4e-43 Identities = 113/276 (40%), Positives = 147/276 (53%), Gaps = 22/276 (7%) Query: 1077 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAA---HGVANEDPVQGVANEDAVQGVANEVE 1133 E + + + H+D G E V+ +VA +ED V + NEDA + NE Sbjct: 88 EASEESLVHKDRGDG---ERPVNVRVVQVAPLRRESTPHEDTVHNITNEDASHDITNEDA 144 Query: 1134 VQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIAN 1193 V G+A+E A QGIANEDAA GIANE AAHGIA+EDAAQGIANE AAQGIA+EDA QGIAN Sbjct: 145 VHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQGIANEDAAQGIAN 204 Query: 1194 EDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHG 1253 EDAVHG+A E AAHG+ANEDA H IA D+ IANE A IA + V + Sbjct: 205 EDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIANDTVQGTLTRM----- 259 Query: 1254 VANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGV----- 1308 + K ++ + + + K + + K P++ + Sbjct: 260 LYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLL 319 Query: 1309 ------ANEDPIQGVANEVEVQGVAHEDAVQGIANE 1338 AN D + +ANE V +A+E AV IAN+ Sbjct: 320 MIPTRHANADTVHDIANEDSVYDIANEGAVYDIAND 355 Score = 175 bits (444), Expect = 4e-43 Identities = 106/245 (43%), Positives = 135/245 (55%), Gaps = 12/245 (4%) Query: 607 QGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAK 666 + +ED VH + NEDA+ I E HG+ANE A QG+ NEDA G +ANEDAA IA Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQG-IANEDAAHGIAS 177 Query: 667 PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG 726 DAA GIANEVAA GIANEDAAQGIANEDA GIANE AAHGI+ EDAV GIANED+ Sbjct: 178 EDAAQGIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYD 237 Query: 727 IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDA 786 IA+EDA+ IAN+ + + + + V + + + + Sbjct: 238 IANEDAIYDIANDTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLY 297 Query: 787 VQGIANEDAAHGIANEVAAHGV--------ANEDAAQGVANEDAAQGVANEDAVHGVANE 838 + A + + A + AN D +ANED+ +ANE AV+ +AN Sbjct: 298 TTSLMT--APYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIAN- 354 Query: 839 DAAQG 843 D QG Sbjct: 355 DTVQG 359 Score = 175 bits (443), Expect = 5e-43 Identities = 104/239 (43%), Positives = 129/239 (53%), Gaps = 15/239 (6%) Query: 129 QGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANE 188 + +ED V + NEDA I NEDA HGIANE AAQGIANEDAAQ IA EDAA IA+E Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASE 178 Query: 189 DAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGV 248 DAAQGI+ E A QGIANEDAAQGIA ED V G+ANED G+ANEDAV G+ANE V + Sbjct: 179 DAAQGIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDI 238 Query: 249 AHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAN----EDAAQGIAHEDAVQGIAN 304 A+EDA+ IAN+ +T + + + + + + + Sbjct: 239 ANEDAIYDIANDTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYT 298 Query: 305 EDAVHGVAKEVAAHGV-----------ANEDAAHAIAKPDAAHGIANEVATQGIATEDV 352 + K + AN D H IA D+ + IANE A IA + V Sbjct: 299 TSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIANDTV 357 Score = 175 bits (443), Expect = 5e-43 Identities = 102/237 (43%), Positives = 135/237 (56%), Gaps = 16/237 (6%) Query: 924 EEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHG 983 E+ I +DA+H ITNEDA G+ANE AA G+ANEDAAQG+ANE AA G+A+EDA G Sbjct: 124 EDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQG 183 Query: 984 VANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDA 1043 +ANE A QG+ANE QGIA++DA+ GIANEDAAHGIANE A HGIANED+ IANEDA Sbjct: 184 IANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDA 243 Query: 1044 AQGIANEVAAHGISK----EDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVH 1099 IAN+ +++ ++ + + + + + + + Sbjct: 244 IYDIANDTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSLMT 303 Query: 1100 GVAKEVAAHGV-----------ANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQG 1145 K + AN D V +ANED+V +ANE V +A+ D VQG Sbjct: 304 APYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIAN-DTVQG 359 Score = 174 bits (441), Expect = 9e-43 Identities = 98/179 (54%), Positives = 118/179 (65%), Gaps = 10/179 (5%) Query: 940 TNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEV 999 T E + + + ++D G + + + +ED VH + NEDA + NE Sbjct: 86 TLEASEESLVHKDRGDGERPVNVRVVQVAPLRRESTPHEDTVHNITNEDASHDITNE--- 142 Query: 1000 QGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKE 1059 DA+ GIANE AA GIANE AA GIANEDAA GIA+EDAAQGIANEVAA GI+ E Sbjct: 143 ------DAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQGIANE 196 Query: 1060 DAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQG 1118 DA QGIANEDA GIANEDAA GIA+EDAV GIANED+V+ +A E A + +AN D VQG Sbjct: 197 DAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIAN-DTVQG 254 Score = 172 bits (436), Expect = 4e-42 Identities = 106/234 (45%), Positives = 127/234 (54%), Gaps = 44/234 (18%) Query: 1166 NEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAR 1225 +ED I NEDA+ I +EDAV GIANE A G+A E AA G+ANEDAAH IA DAA+ Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQ 182 Query: 1226 GIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKED 1285 GIANEVAAQGIA ED A GIANEDA HG+ANE AAHGI+ EDAV GIANED+ IA ED Sbjct: 183 GIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242 Query: 1286 AVQGIANEDAAQG-----------------------------------------IAKEDP 1304 A+ IAN D QG + Sbjct: 243 AIYDIAN-DTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSL 301 Query: 1305 VQGVANEDPIQGVANEVEVQGVAHEDA--VQGIANEDAAHGIANEDAAQGIANE 1356 + P++ + + + H +A V IANED+ + IANE A IAN+ Sbjct: 302 MTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIAND 355 Score = 172 bits (435), Expect = 5e-42 Identities = 90/137 (65%), Positives = 103/137 (75%), Gaps = 1/137 (0%) Query: 991 QGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANE 1050 + +E V I ++DA I NEDA HGIANE AA GIANEDAAQGIANEDAA GIA+E Sbjct: 119 ESTPHEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASE 178 Query: 1051 VAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGV 1110 AA GI+ E A QGIANEDAAQGIANEDA GIA+EDA GIANEDAVHG+A E + + + Sbjct: 179 DAAQGIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDI 238 Query: 1111 ANEDPVQGVANEDAVQG 1127 ANED + +AN D VQG Sbjct: 239 ANEDAIYDIAN-DTVQG 254 Score = 171 bits (432), Expect = 1e-41 Identities = 113/260 (43%), Positives = 136/260 (52%), Gaps = 36/260 (13%) Query: 1776 SVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEV 1835 S E H + NEDA+H I DA GIANE AAQGIA NEDAA G+ANE Sbjct: 120 STPHEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIA---------NEDAAQGIANED 170 Query: 1836 AAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIA 1895 AAHGI+ EDA QGIANE AAQGIA ED QG+ANE DAV GIANEDAAHGIA Sbjct: 171 AAHGIASEDAAQGIANEVAAQGIANEDAAQGIANE---------DAVHGIANEDAAHGIA 221 Query: 1896 NEDAAQGIANEDAAQDIANEDAAQGISKEDAVQG-----IANQDAAQGIAKEDAVQGIAN 1950 NEDA GIANED+ DIANEDA I+ D VQG + + K ++ + Sbjct: 222 NEDAVHGIANEDSVYDIANEDAIYDIA-NDTVQGTLTRMLYTTSLMRTPYKASVMRTLYM 280 Query: 1951 EDAAQGIANEVAAHGIANEDAAQGIANEDAAQGI-----------AHEDAVQGIANEDAV 1999 + + + + + A+ D V IANED+V Sbjct: 281 TSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSV 340 Query: 2000 HGVANEDAAHAIAKPDAARG 2019 + +ANE A + IA D +G Sbjct: 341 YDIANEGAVYDIAN-DTVQG 359 Score = 170 bits (431), Expect = 1e-41 Identities = 100/239 (41%), Positives = 132/239 (55%), Gaps = 8/239 (3%) Query: 530 NEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAH 589 +ED VH + NE A+H + NEDA H IA AA GIANE A QGIA ED A GIA+EDAA Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQ 182 Query: 590 GVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNED 649 G+ANEVA G+A EDA QG+ANEDAVHG+ANEDAA GIA E HG+ANED+V + NED Sbjct: 183 GIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242 Query: 650 ALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGI 709 A++ +AN+ + + + + + + + + Sbjct: 243 AIYD-IANDTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSL 301 Query: 710 S----KEDAVQGIANEDAAQGIAH--EDAVQGIANEDAVHGVAKEVAAHGVANEDPVQG 762 K ++ + H D V IANED+V+ +A E A + +AN D VQG Sbjct: 302 MTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIAN-DTVQG 359 Score = 169 bits (428), Expect = 3e-41 Identities = 108/286 (37%), Positives = 144/286 (50%), Gaps = 28/286 (9%) Query: 721 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAA---HGVANEDPVQGVANEDVVQGVANEVE 777 E + + + H+D G E V+ +VA +ED V + NED + NE Sbjct: 88 EASEESLVHKDRGDG---ERPVNVRVVQVAPLRRESTPHEDTVHNITNEDASHDITNEDA 144 Query: 778 VQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVAN 837 V GIA+E A QGIANEDAA GIANE AAHG+A+EDAAQG+ANE AAQG+ANEDA G+AN Sbjct: 145 VHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQGIANEDAAQGIAN 204 Query: 838 EDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVAN 897 EDA HG+ NEDA G+ NE+A+HG +ANED+ IA DA + IAN+ V Sbjct: 205 EDA---------VHGIANEDAAHGIANEDAVHG-IANEDSVYDIANEDAIYDIANDTVQG 254 Query: 898 EVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGV 957 + T + + + + K ++ + Sbjct: 255 TLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRAL 314 Query: 958 -----------ANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQG 992 AN D +ANE + +ANE AV+ +AN D VQG Sbjct: 315 YTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIAN-DTVQG 359 Score = 168 bits (425), Expect = 7e-41 Identities = 106/252 (42%), Positives = 133/252 (52%), Gaps = 17/252 (6%) Query: 1022 NEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQ 1081 +E H I NEDA+ I NEDA GIANE AA GI+ EDA QGIANEDAA GIA+EDAAQ Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQ 182 Query: 1082 GIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHED 1141 GIA+E A QGIANEDA G+A E A HG+ANED G+ANEDAV G+AN ED Sbjct: 183 GIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIAN---------ED 233 Query: 1142 AVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVA 1201 +V IANEDA + IAN+ + + + ++ + + Sbjct: 234 SVYDIANEDAIYDIANDTVQGTLTRMLYTTSLMRTPYKASV-----MRTLYMTSLTRTLY 288 Query: 1202 KEVAAHGVANEDAAHAIAKPDAARGIANE--VAAQGIATEDVADGIANEDAAHGVANEVA 1259 K + A K R + + A D IANED+ + +ANE A Sbjct: 289 KPSLTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGA 348 Query: 1260 AHGISKEDAVQG 1271 + I+ D VQG Sbjct: 349 VYDIA-NDTVQG 359 Score = 168 bits (425), Expect = 7e-41 Identities = 89/142 (62%), Positives = 101/142 (71%), Gaps = 10/142 (7%) Query: 1247 NEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQ 1306 +ED H + NE A+H I+ EDAV GIANE AAQGIA NEDAAQGIA ED Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIA---------NEDAAQGIANEDAAH 173 Query: 1307 GVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANED 1366 G+A+ED QG+ANEV QG+A+EDA QGIANEDA HGIANEDAA GIANEDA IANED Sbjct: 174 GIASEDAAQGIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANED 233 Query: 1367 AAQGISKEDAVQGIANEDAAQG 1388 + I+ EDA+ IAN D QG Sbjct: 234 SVYDIANEDAIYDIAN-DTVQG 254 Score = 167 bits (424), Expect = 9e-41 Identities = 109/281 (38%), Positives = 140/281 (49%), Gaps = 40/281 (14%) Query: 450 EDAAQGIAHEDAAQGIAHEDA----VQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPD 505 E + + + H+D G + V + E H E H + N+DA+H I D Sbjct: 88 EASEESLVHKDRGDGERPVNVRVVQVAPLRRESTPH----EDTVHNITNEDASHDITNED 143 Query: 506 AARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIA 565 A GIANE AAQGIA ED A GIANEDA HG+A+E AA G+ANE AA GIA Sbjct: 144 AVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQ---------GIA 194 Query: 566 NEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQ 625 NE A QGIA ED GIANEDAAHG+ANE AVHG+A ED+V +ANEDA++ +AN+ Sbjct: 195 NEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIANDTVQG 254 Query: 626 GIAKEVTAHGVANEDAVQGVVN------------EDALHGVVANEDAAQAIAKPDAAHGI 673 + + + + V+ + +L + A K + Sbjct: 255 TLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRAL 314 Query: 674 -----------ANEVAAHGIANEDAAQGIANEDAAQGIANE 703 AN H IANED+ IANE A IAN+ Sbjct: 315 YTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIAND 355 Score = 167 bits (423), Expect = 1e-40 Identities = 103/239 (43%), Positives = 130/239 (54%), Gaps = 8/239 (3%) Query: 1445 NEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAR 1504 +ED I NEDA+ I +EDAV GIANE A G+A E AA G+ANEDAAH IA DAA+ Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQ 182 Query: 1505 GIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEV 1564 GIANEVA QGIA ED A GIANEDA HG+ANE AA GIANE AVHG+A ED+V + E Sbjct: 183 GIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242 Query: 1565 TAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGI 1624 + +AN D VQG + + + ++ + + + S+ + Sbjct: 243 AIYDIAN-DTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSL 301 Query: 1625 ANQDAAQGIANEVAAHGI------SKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQG 1677 + + + D V IANED+ IANE A IA+ D VQG Sbjct: 302 MTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIAN-DTVQG 359 Score = 167 bits (423), Expect = 1e-40 Identities = 106/243 (43%), Positives = 129/243 (53%), Gaps = 31/243 (12%) Query: 1950 NEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAH 2009 +ED I NE A+H I NEDA GIANE AAQGIA+EDA QGIANEDA HG+A+EDAA Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQ 182 Query: 2010 AIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEG 2069 IA AA+GIANE AAQGIA ED GIANEDAAHG+ANEDA IA D+ + IAN Sbjct: 183 GIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIAN-- 240 Query: 2070 IATEDVADGIAEDAVQG-ITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDA 2128 ED IA D VQG +T ++ + + + +T + + Sbjct: 241 ---EDAIYDIANDTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLY 297 Query: 2129 AHGV------------------------ANEVAAHGVANEDAAQGVANEVAAQGVANEDA 2164 + AN H +ANED+ +ANE A +AN D Sbjct: 298 TTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIAN-DT 356 Query: 2165 VQG 2167 VQG Sbjct: 357 VQG 359 Score = 167 bits (423), Expect = 1e-40 Identities = 87/134 (64%), Positives = 103/134 (76%), Gaps = 2/134 (1%) Query: 1580 NEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAA 1639 +ED +H++ NEDA+ I DA HGIANE AA IAN+DAAQGIAN+DAA GIA+E AA Sbjct: 123 HEDTVHNIT-NEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAA 181 Query: 1640 HGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANE 1699 GI+ E A QGIANEDAAQGIANEDA GIA+EDA GIANEDAVHG+A E + + +ANE Sbjct: 182 QGIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANE 241 Query: 1700 DPVQGVANEDAVQG 1713 D + +AN D VQG Sbjct: 242 DAIYDIAN-DTVQG 254 Score = 166 bits (421), Expect = 2e-40 Identities = 103/241 (42%), Positives = 135/241 (56%), Gaps = 18/241 (7%) Query: 422 NEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVH 481 +ED I NE A+H I+ EDAV GIANE AAQGIA+EDAAQGIA+EDA GIA+EDA Sbjct: 123 HEDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQ 182 Query: 482 GVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEV 541 G+A EVAA G+AN+DAA IA DA GIANE AA GIA ED GIANED+V+ +ANE Sbjct: 183 GIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242 Query: 542 AAHGVANEDAAHAIA-------------KPDAAHGIANEVATQGIATEDVADGIANED-- 586 A + +AN+ + K + T+ + + + Sbjct: 243 AIYDIANDTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSLM 302 Query: 587 -AAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGV 645 A + + A++ + + AN D VH +ANED+ IA E + +AN D VQG Sbjct: 303 TAPYKTSPMRALYTTLLMIPTRH-ANADTVHDIANEDSVYDIANEGAVYDIAN-DTVQGT 360 Query: 646 V 646 + Sbjct: 361 L 361 Score = 159 bits (401), Expect = 4e-38 Identities = 102/234 (43%), Positives = 130/234 (55%), Gaps = 9/234 (3%) Query: 1554 EDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAH 1613 ED V + E +H + NEDAV G+ NE A + ANEDAAQ IA DAAHGIA+E AA Sbjct: 124 EDTVHNITNEDASHDITNEDAVHGIANEAAAQGI-ANEDAAQGIANEDAAHGIASEDAAQ 182 Query: 1614 SIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHED 1673 IAN+ AAQGIAN+DAAQGIANE A HGI+ EDA GIANEDA GIANED+ IA+ED Sbjct: 183 GIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242 Query: 1674 AVQGIANEDAVHGVAKEVAAHGVANEDP----VQGVANEDAVQGVANEVEVQGVAHEDAV 1729 A+ IAN D V G + P V ++ + + + ++ Sbjct: 243 AIYDIAN-DTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSL 301 Query: 1730 QGIANEDA---AHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKE 1780 + + A T + AN D IA+ED+V IANE AV+ +A + Sbjct: 302 MTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIAND 355 Score = 155 bits (393), Expect = 3e-37 Identities = 108/284 (38%), Positives = 143/284 (50%), Gaps = 19/284 (6%) Query: 1455 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQG 1514 E + + + H+D G E V+ +VA + E H D I NE A+ Sbjct: 88 EASEESLVHKDRGDG---ERPVNVRVVQVAP--LRRESTPHE----DTVHNITNEDASHD 138 Query: 1515 IATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDA 1574 I ED GIANE AA G+ANE AAQGIANE A HG+A EDA QG+ EV A G+ANEDA Sbjct: 139 ITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQGIANEVAAQGIANEDA 198 Query: 1575 VQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIA 1634 QG+ NEDA+H +ANEDAA IA DA HGIANE + + IAN+DA IAN D QG Sbjct: 199 AQGIANEDAVHG-IANEDAAHGIANEDAVHGIANEDSVYDIANEDAIYDIAN-DTVQGTL 256 Query: 1635 NEV-----AAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAK 1689 + K ++ + + + + + + + + Sbjct: 257 TRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSLMTAPYKTSPMRALYT 316 Query: 1690 EVAAHGV--ANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQG 1731 + AN D V +ANED+V +ANE V +A+ D VQG Sbjct: 317 TLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIAN-DTVQG 359 Score = 154 bits (389), Expect = 1e-36 Identities = 97/249 (38%), Positives = 131/249 (52%), Gaps = 29/249 (11%) Query: 885 DAAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDA 944 D H I NE +++ I ED GIA +A AAQ IA +DAA I NEDA Sbjct: 125 DTVHNITNEDASHD-----ITNEDAVHGIANEA--------AAQGIANEDAAQGIANEDA 171 Query: 945 AQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAH 1004 A G+A+EDAA G+ANE AAQG+ANE AAQG+ANEDAVHG+ANEDA G+ANE V GIA+ Sbjct: 172 AHGIASEDAAQGIANEVAAQGIANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIAN 231 Query: 1005 KDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGIS----KED 1060 +D++ IANEDA + IAN+ + + + + ++ K Sbjct: 232 EDSVYDIANEDAIYDIANDTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPS 291 Query: 1061 AVQGIANEDAAQGIANEDAAQGI-----------AHEDAVQGIANEDAVHGVAKEVAAHG 1109 + + + + A+ D V IANED+V+ +A E A + Sbjct: 292 LTRTLYTTSLMTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYD 351 Query: 1110 VANEDPVQG 1118 +AN D VQG Sbjct: 352 IAN-DTVQG 359 Score = 149 bits (375), Expect = 4e-35 Identities = 94/241 (39%), Positives = 122/241 (50%), Gaps = 18/241 (7%) Query: 1518 EDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQG 1577 ED I NEDA+H + NE A GIANE A G+A EDA QG+ E AHG+A+EDA QG Sbjct: 124 EDTVHNITNEDASHDITNEDAVHGIANEAAAQGIANEDAAQGIANEDAAHGIASEDAAQG 183 Query: 1578 VVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEV 1637 + NE A + ANEDAAQ IA DA HGIANE AAH IAN+DA GIAN+D+ IANE Sbjct: 184 IANEVAAQGI-ANEDAAQGIANEDAVHGIANEDAAHGIANEDAVHGIANEDSVYDIANED 242 Query: 1638 AAHGISKEDAVQG-----IANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVA 1692 A + I+ D VQG + + + + + + + Sbjct: 243 AIYDIAN-DTVQGTLTRMLYTTSLMRTPYKASVMRTLYMTSLTRTLYKPSLTRTLYTTSL 301 Query: 1693 AHGVANEDPVQGV-----------ANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGI 1741 P++ + AN D V +ANE V +A+E AV IAN+ + Sbjct: 302 MTAPYKTSPMRALYTTLLMIPTRHANADTVHDIANEDSVYDIANEGAVYDIANDTVQGTL 361 Query: 1742 T 1742 T Sbjct: 362 T 362 Score = 34.7 bits (78), Expect = 1.1 Identities = 16/37 (43%), Positives = 22/37 (59%), Gaps = 1/37 (2%) Query: 827 ANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVV 863 AN D VH +ANED+ +A E + + N D VQG + Sbjct: 326 ANADTVHDIANEDSVYDIANEGAVYDIAN-DTVQGTL 361 Score = 32.7 bits (73), Expect = 4.4 Identities = 14/37 (37%), Positives = 21/37 (56%) Query: 818 ANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVT 854 AN D +ANED+V+ +ANE A +A + +T Sbjct: 326 ANADTVHDIANEDSVYDIANEGAVYDIANDTVQGTLT 362 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 125 bits (313), Expect = 6e-28 Identities = 227/1121 (20%), Positives = 301/1121 (26%), Gaps = 74/1121 (6%) Query: 405 PDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQG 464 P G E A G D G G G+ AAQ D G Sbjct: 133 PRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAG 192 Query: 465 IAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDV 524 A +QG G A G P +G E G++ Sbjct: 193 GAQLGVMQGPMGPMGPRGPPGPAGAPG------------PQGFQGNPGEPGEPGVSGPMG 240 Query: 525 ADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIAN 584 G G E G A E P G T G+ G Sbjct: 241 PRGPPGPPGKPGDDGEAGKPGKAGERG------PPGPQGARGFPGTPGLPGVKGHRGYPG 294 Query: 585 EDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQG 644 D A G A V G + G G+ E G A A G D G Sbjct: 295 LDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARG---NDGQPG 351 Query: 645 VVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEV 704 G A G E G + AQG E G Sbjct: 352 PAGPPGPVGPAGGPGFP-------GAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPA 404 Query: 705 AAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVA 764 A G D + G A GIA G G + G E + G Sbjct: 405 GASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFK 464 Query: 765 NEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQ 824 E +G QG G A E+ G E G +G Sbjct: 465 GEQGPKGEPGPAGPQG------APGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFP 518 Query: 825 GVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKP 884 G G E G+A A+G G+ L G + Q P Sbjct: 519 GQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGR-PGDAGPQGKVGP 577 Query: 885 DAAHGIANEGVANEVAAQGIATEDVADGI-AKDAAHGITKEEAAQAIAKQDAAHSITNED 943 A G +G QG + G A+G + + + + +D Sbjct: 578 SGAPG--EDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKD 635 Query: 944 AAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIA 1003 G A G A E QG QG+ G + QGV E G+ Sbjct: 636 GETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLV 695 Query: 1004 HKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQ 1063 +G E + G A G+ G D +G + G +Q Sbjct: 696 GPRGERGFPGERGSPG------AQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQ 749 Query: 1064 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANED 1123 G+ E A GIA +G E +G +D G+ + G A Sbjct: 750 GMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPA------------ 797 Query: 1124 AVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIA 1183 G EV G A G A A G E G A G A A G Sbjct: 798 GANGEKGEVGPPGPA------GSAGARGAPGERGETGPPGPA------GFAGPPGADGQP 845 Query: 1184 HEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVAD 1243 QG A + G G + P ARG A G A Sbjct: 846 GAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPG---AA 902 Query: 1244 GIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKED 1303 G ++G G S +D +G + G A E +QG A +G +D Sbjct: 903 GRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDD 962 Query: 1304 PVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIA 1363 G QG+A + + G+ + +G G + A G + + Sbjct: 963 GPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPV 1022 Query: 1364 NEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQ 1423 G + E +G D G V+G E G G Sbjct: 1023 GPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPT 1082 Query: 1424 GIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEV 1483 G + G + G A QG +G A E +G+ G+ Sbjct: 1083 GKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLP 1142 Query: 1484 AAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGI 1524 G + + A A P RG V G +D A+GI Sbjct: 1143 GPPGPSGDQGASGPAGPSGPRGPPGPVGPSG---KDGANGI 1180 Score = 122 bits (307), Expect = 3e-27 Identities = 202/1045 (19%), Positives = 287/1045 (27%), Gaps = 51/1045 (4%) Query: 1221 PDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQG 1280 P G+ AAQ D G A G + G G G Sbjct: 169 PPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPG 228 Query: 1281 IAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDA 1340 E V G G + G A + G QG G+ Sbjct: 229 EPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKG 288 Query: 1341 AHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVAN 1400 G D A+G E A + E + G + G +G G Sbjct: 289 HRGYPGLDGAKG---EAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARG 345 Query: 1401 EDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQG 1460 D G A G A G A G E G + AQG E G Sbjct: 346 NDGQPGPAGPPGPVGPAGGPGFPG------APGAKGEAGPTGARGPEGAQGPRGEPGTPG 399 Query: 1461 IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDV 1520 G D + G A G+A P +G + +G E Sbjct: 400 SPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPG 459 Query: 1521 ADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVN 1580 G E G QG G G V + G +G Sbjct: 460 IAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPG 519 Query: 1581 EDALHSV--VANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVA 1638 +D L E +A P A+G + A+G+ + G +V Sbjct: 520 QDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG---ARGLTGRPGDAGPQGKVG 576 Query: 1639 AHGISKEDA---------------VQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDA 1683 G ED V G A G + +G+ ++G+ +D Sbjct: 577 PSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDG 636 Query: 1684 VHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITN 1743 G A G A E QG QG+ G + QG+ E A G+ Sbjct: 637 ETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVG 696 Query: 1744 EVAAHGIANE---DAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDA 1800 G E AQG+ + G D + G + Sbjct: 697 PRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERG 756 Query: 1801 ARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAK 1860 A GIA +G E +G P +D G+ + G + + +G G A Sbjct: 757 AAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAG 816 Query: 1861 EDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQG 1920 G E G A G + A G E +G A Q + QG Sbjct: 817 ARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQG 876 Query: 1921 ISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDA 1980 + +G G G + G G + +D +G + Sbjct: 877 PTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSG 936 Query: 1981 AQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIAN 2040 G A E +QG A G +D P +G+A + G+ + G Sbjct: 937 PPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPG 996 Query: 2041 EDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQD 2100 G + A P A+ G G A + G A +D Sbjct: 997 LPGPSGEPGKQGA-----PGASGDRGPPGPVGPPGLTGPAGE--PGREGSPGADGPPGRD 1049 Query: 2101 AAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQ------GVANEV 2154 A G+ + +G T V A G + G A G E AQ G A Sbjct: 1050 GAAGVKGD---RGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGAR 1106 Query: 2155 AAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVA 2214 QG +G A E +G+ G+ G + + A G A +G Sbjct: 1107 GIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPP 1166 Query: 2215 NEVAAQGVANEDAAQGVANEVAVHG 2239 V G + +D A G+ + G Sbjct: 1167 GPV---GPSGKDGANGIPGPIGPPG 1188 Score = 118 bits (295), Expect = 8e-26 Identities = 214/1061 (20%), Positives = 291/1061 (27%), Gaps = 74/1061 (6%) Query: 1231 VAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGI 1290 V I EDV D ++ E G + ++ G + G K+ + G Sbjct: 62 VLCDDIICEDVKDCLSPE-IPFGECCPICPTDLATASGQPGPKGQKGEPGDIKD--IVGP 118 Query: 1291 ANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAA 1350 QG A E +G +G E G D G G Sbjct: 119 KGPPGPQGPAGEQGPRGD------RGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGP 172 Query: 1351 QGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANE 1410 G+ AAQ D G ++ +QG +G G QG E Sbjct: 173 PGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRG---PPGPAGAPGPQGFQGNPGE 229 Query: 1411 VEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGI 1470 GV+ +G G E G A E G G V+G Sbjct: 230 PGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGH 289 Query: 1471 ANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAA 1530 + G E A GV E + G + +G+ E G A A Sbjct: 290 RGYPGLDGAKGEAGAPGVKGESGS------PGENGSPGPMGPRGLPGERGRTGPAGAAGA 343 Query: 1531 HGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVAN 1590 G + G V G G E G + QG E + Sbjct: 344 RGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPG---TPGS 400 Query: 1591 EDAAQAIAKP--DAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAV 1648 A A P D G A IA G QG + G + E + Sbjct: 401 PGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGI 460 Query: 1649 QGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANE 1708 G E +G QG G A E+ G E G +G Sbjct: 461 AGFKGEQGPKGEPGPAGPQG------APGPAGEEGKRGARGEPGGVGPIGPPGERGAPGN 514 Query: 1709 DAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGI 1768 G +G E G+A A+G G+ G + QG Sbjct: 515 RGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQG- 573 Query: 1769 ANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAA 1828 +V G ED P ARG + G P A Sbjct: 574 -----------KVGPSGAPGEDGRPGPPGPQGARGQPGVM------------GFPGPKGA 610 Query: 1829 HGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANE 1888 +G + G+ ++G+ +D G A G A E QG QG+ Sbjct: 611 NGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGP 670 Query: 1889 DAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGI 1948 G + QG+ E A + +G E G AQG+ + G Sbjct: 671 PGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPG------AQGLQGPRGLPGT 724 Query: 1949 ANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAA 2008 D +G + G QG+ E A GIA +G E G +D Sbjct: 725 PGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGG 784 Query: 2009 HAIAKP------DAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAA 2062 + P A G EV G A A G E G A P A Sbjct: 785 RGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGE---RGETGPPGPAGFAGPPGA 841 Query: 2063 HGIANEGIATEDVADGIAEDA----VQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEV 2118 G G E G DA QG + Q G G T Sbjct: 842 DG--QPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFP 899 Query: 2119 AAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIA 2178 A G ++G G + +D +G + G A E +QG A +G Sbjct: 900 GAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEP 959 Query: 2179 HKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVH 2238 D G QG+A + G+ + +G G + A G + + Sbjct: 960 GDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPP 1019 Query: 2239 GVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVHGIANE 2279 G A E +G D G V G E Sbjct: 1020 GPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGE 1060 Score = 115 bits (289), Expect = 4e-25 Identities = 218/1118 (19%), Positives = 299/1118 (26%), Gaps = 75/1118 (6%) Query: 667 PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG 726 P G E A G D G G G+ A Q D G Sbjct: 133 PRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAG 192 Query: 727 IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDA 786 A +QG G A G QG E GV+ + +G Sbjct: 193 GAQLGVMQGPMGPMGPRGPPGPAGAPGPQG---FQGNPGEPGEPGVSGPMGPRGPPGPPG 249 Query: 787 VQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAK 846 G E G A E G G +G + G E A GV Sbjct: 250 KPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKG 309 Query: 847 EVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIAT 906 E G E+ G + L G A AA N+G G Sbjct: 310 E---SGSPGENGSPGPMGPRGLPGERGRTGPA------GAAGARGNDGQPGPAGPPGPVG 360 Query: 907 EDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGV 966 A G A G E + A E G A G D G Sbjct: 361 P--AGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGA 418 Query: 967 ANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGI---ANE 1023 A G+A G QG + +G + I G E G A Sbjct: 419 KGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGP 478 Query: 1024 VAAHGIANEDAAQGIANEDAAQGIANEVAAHG------ISKEDAV---QGIANEDAAQGI 1074 A G A E+ +G E G G +D + +G E G+ Sbjct: 479 QGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGL 538 Query: 1075 ANEDAAQGIAHEDA------VQGIANEDAVHGVAKEVAAHGVANEDP------VQGVANE 1122 A A G +G+ G +V G ED QG + Sbjct: 539 AGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ 598 Query: 1123 DAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGI 1182 V G G + +G+ G+ + G A G A E QG Sbjct: 599 PGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGA 658 Query: 1183 AHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVA 1242 QG+ G + GV E A + P RG E + G A Sbjct: 659 PGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPG------A 712 Query: 1243 DGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKE 1302 G+ G G S G QG+ E GIA +G E Sbjct: 713 QGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGE 772 Query: 1303 DPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDI 1362 +G +D +G+ + G A + +G G A A G E Sbjct: 773 KGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGP 832 Query: 1363 ANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAV 1422 A G + +G E +G A QG + QG +G Sbjct: 833 AGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP 892 Query: 1423 QGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE 1482 G A G ++G G + +D +G + G A E + G A Sbjct: 893 PGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGP 952 Query: 1483 VAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGI 1542 G +D P +G+A + G+ + G G + A G Sbjct: 953 PGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGA 1012 Query: 1543 ANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDA 1602 + + G + G E G D G D V + A+ P A Sbjct: 1013 SGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPG---RDGAAGVKGDRGETGAVGAPGA 1069 Query: 1603 AHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAN 1662 + G A QG E A G G QG Sbjct: 1070 P-------------GPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRG 1116 Query: 1663 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQG 1722 + +G A E +G+ G+ G + + G A +G V Sbjct: 1117 D---KGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPV---- 1169 Query: 1723 VAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIA 1760 G + +D A+GI + G G A Sbjct: 1170 --------GPSGKDGANGIPGPIGPPGPRGRSGETGPA 1199 Score = 115 bits (287), Expect = 7e-25 Identities = 197/1028 (19%), Positives = 277/1028 (26%), Gaps = 61/1028 (5%) Query: 65 AHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVAN 124 A G + GV +G D A G A G + G + +G+ Sbjct: 274 ARGFPGTPGLPGVKGH---RGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPG 330 Query: 125 EDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQD 184 E G A +G + G G A G E + AQ Sbjct: 331 ERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQG 390 Query: 185 IANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVE 244 E G G D G G+A G QG + Sbjct: 391 PRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLG 450 Query: 245 VQGVAHEDAVQGIANEDAAHGITNEV---AAHGIANEDAAQGIANEDAAQGIAHEDAVQG 301 +G E + G E G A G A E+ +G E G +G Sbjct: 451 PKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERG 510 Query: 302 IANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDA 361 G G E +A P A+G G+ A G+ Sbjct: 511 APGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG---ARGLTGRPG 567 Query: 362 AHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIA 421 G +V G ED G G G A+G Sbjct: 568 DAGPQGKVGPSGAPGEDGRPGPPGPQGARG-------------QPGVMGFPGPKGANGEP 614 Query: 422 NEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVH 481 + +G+ G+ +D G A G A E QG QG+ Sbjct: 615 GKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPP 674 Query: 482 GVAKEVAAHGVANKDAAHAIAKPDAARGIANE---VAAQGIATEDVADGIANEDAVHGVA 538 G + GV + A + P RG E AQG+ G D G + Sbjct: 675 GEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGAS 734 Query: 539 NEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVH 598 G + A GIA +G E +G +D G+ + Sbjct: 735 GPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPP 794 Query: 599 GVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGV--VA 656 G A + +G G A A G E G A G + G A Sbjct: 795 GPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEA 854 Query: 657 NEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQ 716 + P G G+ A+G A G A G Sbjct: 855 GQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFP---GAAGRVGPPGSN 911 Query: 717 GIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEV 776 G G + +D +G + G A E G A +G +D G Sbjct: 912 GNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPP 971 Query: 777 EVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVA 836 QG+A + + G+ + G G + A G + + G + G A Sbjct: 972 GPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA 1031 Query: 837 NEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVA 896 E +G A G D GV + G V A P A +G Sbjct: 1032 GEPGREG---SPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDR 1088 Query: 897 NEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHG 956 E AQG G A GI + + +G A E G Sbjct: 1089 GEAGAQGPMGPSGPAG-----ARGIQGPQGPR---------------GDKGEAGEPGERG 1128 Query: 957 VANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDA 1016 + G+ G + + G A +G V G + KD GI Sbjct: 1129 LKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPV---GPSGKDGANGIPGPIG 1185 Query: 1017 AHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAH-GISKE----DAVQGIANEDAA 1071 G G A G G +++A G+ D +Q + + AA Sbjct: 1186 PPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAA 1245 Query: 1072 QGIANEDA 1079 G+ DA Sbjct: 1246 GGLRQHDA 1253 Score = 114 bits (284), Expect = 1e-24 Identities = 203/1050 (19%), Positives = 280/1050 (26%), Gaps = 75/1050 (7%) Query: 1253 GVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANED 1312 G E A G D G G G+ AAQ D G A Sbjct: 138 GDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLG 197 Query: 1313 PIQGVANEVEVQGV---AHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQ 1369 +QG + +G A QG G G +D Sbjct: 198 VMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEA 257 Query: 1370 GISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANED 1429 G + +G A+G + GV G+ +G A V+G + Sbjct: 258 GKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDG---AKGEAGAPGVKGESGSP 314 Query: 1430 AAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVA 1489 +G + G+ E G A A+G + G G A G Sbjct: 315 GENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAK 374 Query: 1490 NEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVH 1549 E P+ A+G E T G A G D G A GIA Sbjct: 375 GEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFP 434 Query: 1550 GVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVV--ANEDAAQAIAKPDAAHGIA 1607 G QG + G E + G E A A A + G Sbjct: 435 GPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGAR 494 Query: 1608 NEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQ 1667 E +G G G E G+A A G Sbjct: 495 GEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEP 554 Query: 1668 GIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDP---------------VQGVANEDAVQ 1712 G+ +G+ G +V G ED V G Sbjct: 555 GLP---GARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGAN 611 Query: 1713 GVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANED 1772 G + +G+ ++G+ +D G G A E QG QG+ Sbjct: 612 GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPP 671 Query: 1773 AVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANE---VAAQGIATEDVADGIPNEDAAH 1829 + GV E A + P RG E AQG+ G P D Sbjct: 672 GPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPK 731 Query: 1830 GVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANED 1889 G + G +QG+ E A GIA +G E +G +D +G+ Sbjct: 732 GASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPI 791 Query: 1890 AAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIA 1949 G A + +G A A G E G A G A G Sbjct: 792 GPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPA------GFAGPPGADG-- 843 Query: 1950 NEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAH 2009 + A+G E G A QG + QG +G G A Sbjct: 844 -QPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAA 902 Query: 2010 AIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEG 2069 P + G G + +D G + G A E Q A P G + Sbjct: 903 GRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGD- 961 Query: 2070 IATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAA 2129 D G Q +A Q G+ + +G G + A Sbjct: 962 ------------DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGA 1009 Query: 2130 HGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANE 2189 G + + G G A E +G D G +D G+ + Sbjct: 1010 PGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPG------------RDGAAGVKGD 1057 Query: 2190 DAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGV---ANEVAVHGVANEDAA 2246 +G V A G + G A QG E AQG + G+ Sbjct: 1058 ---RGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGP 1114 Query: 2247 RHMAKEDAAQGIANEDAAHGIANEDAVHGI 2276 R +G A E G+ G+ Sbjct: 1115 R------GDKGEAGEPGERGLKGHRGFTGL 1138 Score = 110 bits (274), Expect = 2e-23 Identities = 227/1147 (19%), Positives = 304/1147 (26%), Gaps = 102/1147 (8%) Query: 689 QGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE 748 QG A E +G G E G D G G G+ Sbjct: 125 QGPAGEQGPRG------DRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGN 178 Query: 749 VAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGV 808 AA D G A V+QG + +G G A G G Sbjct: 179 FAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRG------PPGPAGAPGPQGFQGNPGEPGE 232 Query: 809 ANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEAL 868 G G +D G + +G A G + GV Sbjct: 233 PGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGY 292 Query: 869 HGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQ 928 G+ +G E A G+ E + G +G + Sbjct: 293 PGL---------------------DGAKGEAGAPGVKGESGSPG-----ENGSPGPMGPR 326 Query: 929 AIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVA---AQGVANEDAVHGVA 985 + + T A G D G A G A A G E G Sbjct: 327 GLPGERGR---TGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGAR 383 Query: 986 NEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQ 1045 + QG E G G D G A GIA G Q Sbjct: 384 GPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQ 443 Query: 1046 GIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEV 1105 G + G + E + G E +G QG G A E+ G E Sbjct: 444 GATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQG------APGPAGEEGKRGARGEP 497 Query: 1106 AAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIA 1165 G +G G +G E G+A A+G G+ Sbjct: 498 GGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLP 557 Query: 1166 NEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAR 1225 G + QG +V G ED P AR Sbjct: 558 GARGLTGRPGDAGPQG---------------------KVGPSGAPGEDGRPGPPGPQGAR 596 Query: 1226 GIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKED 1285 G + G A+G + G+ G+ +D G A G A E Sbjct: 597 G---QPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGER 653 Query: 1286 AVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANE---DAAH 1342 QG QG+ G + QGV E G+ +G E A Sbjct: 654 GEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQ 713 Query: 1343 GIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANED 1402 G+ G D + + G +QG+ E A GIA +G E Sbjct: 714 GLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEK 773 Query: 1403 AVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIA 1462 +G + +G+ G A A+G EV G A A+G E G Sbjct: 774 GPEGAPGKDGGRGLTGPIGPPGPA---GANGEKGEVGPPGPAGSAGARGAPGERGETGPP 830 Query: 1463 HEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVAD 1522 G D G E G + A P A G G A Sbjct: 831 GPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQ 890 Query: 1523 GIANEDAAHGVANEV---AAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVV 1579 G G A V + G G + +D +G + G A E +QG Sbjct: 891 GPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPA 950 Query: 1580 NEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAA 1639 +D P G+A + + + +G G + A Sbjct: 951 GPPG-EKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGA 1009 Query: 1640 HGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE---VAAHGV 1696 G S + G G A E +G D G V G E V A G Sbjct: 1010 PGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGA 1069 Query: 1697 ANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAA 1756 G A QG E QG G + A GI G Sbjct: 1070 PGPPGSPGPAGPTGKQGDRGEAGAQG------PMGPSGPAGARGIQGPQGPRG------D 1117 Query: 1757 QGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATE 1816 +G A E +G+ + G + + A A P RG V G + Sbjct: 1118 KGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSG---K 1174 Query: 1817 DVADGIP 1823 D A+GIP Sbjct: 1175 DGANGIP 1181 Score = 108 bits (269), Expect = 8e-23 Identities = 222/1123 (19%), Positives = 299/1123 (26%), Gaps = 69/1123 (6%) Query: 75 QGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANE 134 +G E A G D G G G+ AAQ D G A Sbjct: 137 RGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQL 196 Query: 135 DAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQGI 194 +QG +G A G QG E ++ + G Sbjct: 197 GVMQGPMGPMGPRGPPGPAGAPG---PQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGD 253 Query: 195 SKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAV 254 E G A E G G V+G + G E GV E Sbjct: 254 DGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGS 313 Query: 255 QGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE 314 G +G + G+ E G A A+G + G G Sbjct: 314 PG------ENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGF 367 Query: 315 VAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKEVTAHGV 374 A G E P+ A G E T G A G D G A G+ Sbjct: 368 PGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGI 427 Query: 375 ANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVA 434 A G G P G E G E +G Sbjct: 428 AGAPGFPGPRGPPGPQGATG----------PLGPKGQTGEPGIAGFKGEQGPKGEPGPAG 477 Query: 435 AHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVAN 494 G G A E+ +G E G +G G G Sbjct: 478 PQG------APGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPG 531 Query: 495 KDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHA 554 + +A P A G G+ A G+ G +V G ED Sbjct: 532 ERGPSGLAGPKGANGDPGRPGEPGLPG---ARGLTGRPGDAGPQGKVGPSGAPGEDGRPG 588 Query: 555 IAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDA 614 P A G + G A+G + G+ + G+ +D G A Sbjct: 589 PPGPQGARG---QPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPG 645 Query: 615 VHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIA 674 G A E QG G+ G + GV E A + P G Sbjct: 646 PAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGV-PGEAGAPGLVGPRGERGFP 704 Query: 675 NE---VAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHED 731 E A G+ G D +G + G +QG+ E A GIA Sbjct: 705 GERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPK 764 Query: 732 AVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIA 791 +G E G + G+ G A + G EV G A G A Sbjct: 765 GDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGAN---GEKGEVGPPGPA------GSA 815 Query: 792 NEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAH 851 A G E G A G + A+G E G A QG + Sbjct: 816 GARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQ 875 Query: 852 GVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVAD 911 G T +G + G AA + P + G G + +D Sbjct: 876 GPTGVTGPKGARGAQGPPGATGFPGAAGRVGPP------GSNGNPGPPGPPGPSGKDGPK 929 Query: 912 GIAKDAAH-GITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEV 970 G D+ G E Q A +D G G+A + G+ + Sbjct: 930 GARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQR 989 Query: 971 AAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIA 1030 +G G + G + + G + G A E G A G Sbjct: 990 GERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREG---SPGADGPP 1046 Query: 1031 NEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGI------A 1084 D A G+ + +G V A G G A QG E AQG A Sbjct: 1047 GRDGAAGVKGD---RGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPA 1103 Query: 1085 HEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQ 1144 +QG G A E G+ G+ G + + G A + Sbjct: 1104 GARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPR 1163 Query: 1145 GI------ANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQG 1181 G + +D A+GI + G G A G Sbjct: 1164 GPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPG 1206 Score = 59.7 bits (143), Expect = 3e-08 Identities = 91/471 (19%), Positives = 129/471 (27%), Gaps = 25/471 (5%) Query: 63 DAAHGITNEDAVQGVANEVAAQGVANEDAAHGVA---------NEVAAHGVANEDAAQGV 113 D G + G QG+ E A G+A E G +D +G+ Sbjct: 728 DGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGL 787 Query: 114 ANEVAAQGVANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAA 173 + G A + +G G A G E G A G + A Sbjct: 788 TGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGA 847 Query: 174 QDIAKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANE 233 + E + A QG S QG +G G G Sbjct: 848 KGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGP 907 Query: 234 DAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGI 293 G G + +D +G + G E G A +G +D G Sbjct: 908 PGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGA 967 Query: 294 AHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVA 353 QG+A + + G+ + G A G + + G Sbjct: 968 EGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGL 1027 Query: 354 DGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIAN 413 G A E G A G D GV + G V A P + G A Sbjct: 1028 TGPAGEPGREG---SPGADGPPGRDGAAGVKGDRGETGAV----GAPGAPGPPGSPGPAG 1080 Query: 414 EVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQG 473 G E AQG + G + +QG +G A E +G+ G Sbjct: 1081 PTGKQGDRGEAGAQG---PMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTG 1137 Query: 474 IANEDAVHGVAKEVAAHGVANKDAAHAIAKP------DAARGIANEVAAQG 518 + G + + A G A P D A GI + G Sbjct: 1138 LQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPG 1188 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 125 bits (313), Expect = 6e-28 Identities = 227/1121 (20%), Positives = 301/1121 (26%), Gaps = 74/1121 (6%) Query: 405 PDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQG 464 P G E A G D G G G+ AAQ D G Sbjct: 64 PRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAG 123 Query: 465 IAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDV 524 A +QG G A G P +G E G++ Sbjct: 124 GAQLGVMQGPMGPMGPRGPPGPAGAPG------------PQGFQGNPGEPGEPGVSGPMG 171 Query: 525 ADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIAN 584 G G E G A E P G T G+ G Sbjct: 172 PRGPPGPPGKPGDDGEAGKPGKAGERG------PPGPQGARGFPGTPGLPGVKGHRGYPG 225 Query: 585 EDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQG 644 D A G A V G + G G+ E G A A G D G Sbjct: 226 LDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARG---NDGQPG 282 Query: 645 VVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEV 704 G A G E G + AQG E G Sbjct: 283 PAGPPGPVGPAGGPGFP-------GAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPA 335 Query: 705 AAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVA 764 A G D + G A GIA G G + G E + G Sbjct: 336 GASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFK 395 Query: 765 NEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQ 824 E +G QG G A E+ G E G +G Sbjct: 396 GEQGPKGEPGPAGPQG------APGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFP 449 Query: 825 GVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKP 884 G G E G+A A+G G+ L G + Q P Sbjct: 450 GQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGR-PGDAGPQGKVGP 508 Query: 885 DAAHGIANEGVANEVAAQGIATEDVADGI-AKDAAHGITKEEAAQAIAKQDAAHSITNED 943 A G +G QG + G A+G + + + + +D Sbjct: 509 SGAPG--EDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKD 566 Query: 944 AAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIA 1003 G A G A E QG QG+ G + QGV E G+ Sbjct: 567 GETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLV 626 Query: 1004 HKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQ 1063 +G E + G A G+ G D +G + G +Q Sbjct: 627 GPRGERGFPGERGSPG------AQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQ 680 Query: 1064 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANED 1123 G+ E A GIA +G E +G +D G+ + G A Sbjct: 681 GMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPA------------ 728 Query: 1124 AVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIA 1183 G EV G A G A A G E G A G A A G Sbjct: 729 GANGEKGEVGPPGPA------GSAGARGAPGERGETGPPGPA------GFAGPPGADGQP 776 Query: 1184 HEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVAD 1243 QG A + G G + P ARG A G A Sbjct: 777 GAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPG---AA 833 Query: 1244 GIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKED 1303 G ++G G S +D +G + G A E +QG A +G +D Sbjct: 834 GRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDD 893 Query: 1304 PVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIA 1363 G QG+A + + G+ + +G G + A G + + Sbjct: 894 GPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPV 953 Query: 1364 NEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQ 1423 G + E +G D G V+G E G G Sbjct: 954 GPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPT 1013 Query: 1424 GIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEV 1483 G + G + G A QG +G A E +G+ G+ Sbjct: 1014 GKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLP 1073 Query: 1484 AAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGI 1524 G + + A A P RG V G +D A+GI Sbjct: 1074 GPPGPSGDQGASGPAGPSGPRGPPGPVGPSG---KDGANGI 1111 Score = 122 bits (307), Expect = 3e-27 Identities = 202/1045 (19%), Positives = 287/1045 (27%), Gaps = 51/1045 (4%) Query: 1221 PDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQG 1280 P G+ AAQ D G A G + G G G Sbjct: 100 PPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPG 159 Query: 1281 IAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDA 1340 E V G G + G A + G QG G+ Sbjct: 160 EPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKG 219 Query: 1341 AHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVAN 1400 G D A+G E A + E + G + G +G G Sbjct: 220 HRGYPGLDGAKG---EAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARG 276 Query: 1401 EDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQG 1460 D G A G A G A G E G + AQG E G Sbjct: 277 NDGQPGPAGPPGPVGPAGGPGFPG------APGAKGEAGPTGARGPEGAQGPRGEPGTPG 330 Query: 1461 IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDV 1520 G D + G A G+A P +G + +G E Sbjct: 331 SPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPG 390 Query: 1521 ADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVN 1580 G E G QG G G V + G +G Sbjct: 391 IAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPG 450 Query: 1581 EDALHSV--VANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVA 1638 +D L E +A P A+G + A+G+ + G +V Sbjct: 451 QDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG---ARGLTGRPGDAGPQGKVG 507 Query: 1639 AHGISKEDA---------------VQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDA 1683 G ED V G A G + +G+ ++G+ +D Sbjct: 508 PSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDG 567 Query: 1684 VHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITN 1743 G A G A E QG QG+ G + QG+ E A G+ Sbjct: 568 ETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVG 627 Query: 1744 EVAAHGIANE---DAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDA 1800 G E AQG+ + G D + G + Sbjct: 628 PRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERG 687 Query: 1801 ARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAK 1860 A GIA +G E +G P +D G+ + G + + +G G A Sbjct: 688 AAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAG 747 Query: 1861 EDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQG 1920 G E G A G + A G E +G A Q + QG Sbjct: 748 ARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQG 807 Query: 1921 ISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDA 1980 + +G G G + G G + +D +G + Sbjct: 808 PTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSG 867 Query: 1981 AQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIAN 2040 G A E +QG A G +D P +G+A + G+ + G Sbjct: 868 PPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPG 927 Query: 2041 EDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQD 2100 G + A P A+ G G A + G A +D Sbjct: 928 LPGPSGEPGKQGA-----PGASGDRGPPGPVGPPGLTGPAGE--PGREGSPGADGPPGRD 980 Query: 2101 AAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQ------GVANEV 2154 A G+ + +G T V A G + G A G E AQ G A Sbjct: 981 GAAGVKGD---RGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGAR 1037 Query: 2155 AAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVA 2214 QG +G A E +G+ G+ G + + A G A +G Sbjct: 1038 GIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPP 1097 Query: 2215 NEVAAQGVANEDAAQGVANEVAVHG 2239 V G + +D A G+ + G Sbjct: 1098 GPV---GPSGKDGANGIPGPIGPPG 1119 Score = 116 bits (291), Expect = 2e-25 Identities = 197/977 (20%), Positives = 265/977 (27%), Gaps = 65/977 (6%) Query: 1315 QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKE 1374 +G E G D G G G+ AAQ D G ++ Sbjct: 68 RGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQL 127 Query: 1375 DAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGI 1434 +QG +G G QG E GV+ +G G Sbjct: 128 GVMQGPMGPMGPRG---PPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGD 184 Query: 1435 ANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAA 1494 E G A E G G V+G + G E A GV E + Sbjct: 185 DGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGS 244 Query: 1495 HAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIE 1554 G + +G+ E G A A G + G V G Sbjct: 245 ------PGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGF 298 Query: 1555 DAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKP--DAAHGIANEVAA 1612 G E G + QG E + A A P D G A Sbjct: 299 PGAPGAKGEAGPTGARGPEGAQGPRGEPG---TPGSPGPAGASGNPGTDGIPGAKGSAGA 355 Query: 1613 HSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHE 1672 IA G QG + G + E + G E +G QG Sbjct: 356 PGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQG---- 411 Query: 1673 DAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGI 1732 G A E+ G E G +G G +G E G+ Sbjct: 412 --APGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGL 469 Query: 1733 ANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAA 1792 A A+G G+ G + QG +V G ED Sbjct: 470 AGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQG------------KVGPSGAPGEDGR 517 Query: 1793 HAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANE 1852 P ARG + G P A+G + G+ ++G+ + Sbjct: 518 PGPPGPQGARGQPGVM------------GFPGPKGANGEPGKAGEKGLPGAPGLRGLPGK 565 Query: 1853 DAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDI 1912 D G A G A E QG QG+ G + QG+ E A + Sbjct: 566 DGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGL 625 Query: 1913 ANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAA 1972 +G E G AQG+ + G D +G + G Sbjct: 626 VGPRGERGFPGERGSPG------AQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGL 679 Query: 1973 QGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKP------DAARGIANEVAA 2026 QG+ E A GIA +G E G +D + P A G EV Sbjct: 680 QGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGP 739 Query: 2027 QGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDA--- 2083 G A A G E G A P A G G E G DA Sbjct: 740 PGPAGSAGARGAPGE---RGETGPPGPAGFAGPPGADG--QPGAKGEQGEAGQKGDAGAP 794 Query: 2084 -VQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVA 2142 QG + Q G G T A G ++G G + Sbjct: 795 GPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPS 854 Query: 2143 NEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAH 2202 +D +G + G A E +QG A +G D G QG+A + Sbjct: 855 GKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIV 914 Query: 2203 GVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANED 2262 G+ + +G G + A G + + G A E +G D Sbjct: 915 GLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGAD 974 Query: 2263 AAHGIANEDAVHGIANE 2279 G V G E Sbjct: 975 GPPGRDGAAGVKGDRGE 991 Score = 115 bits (289), Expect = 4e-25 Identities = 218/1118 (19%), Positives = 299/1118 (26%), Gaps = 75/1118 (6%) Query: 667 PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG 726 P G E A G D G G G+ A Q D G Sbjct: 64 PRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAG 123 Query: 727 IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDA 786 A +QG G A G QG E GV+ + +G Sbjct: 124 GAQLGVMQGPMGPMGPRGPPGPAGAPGPQG---FQGNPGEPGEPGVSGPMGPRGPPGPPG 180 Query: 787 VQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAK 846 G E G A E G G +G + G E A GV Sbjct: 181 KPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKG 240 Query: 847 EVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIAT 906 E G E+ G + L G A AA N+G G Sbjct: 241 E---SGSPGENGSPGPMGPRGLPGERGRTGPA------GAAGARGNDGQPGPAGPPGPVG 291 Query: 907 EDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGV 966 A G A G E + A E G A G D G Sbjct: 292 P--AGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGA 349 Query: 967 ANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGI---ANE 1023 A G+A G QG + +G + I G E G A Sbjct: 350 KGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGP 409 Query: 1024 VAAHGIANEDAAQGIANEDAAQGIANEVAAHG------ISKEDAV---QGIANEDAAQGI 1074 A G A E+ +G E G G +D + +G E G+ Sbjct: 410 QGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGL 469 Query: 1075 ANEDAAQGIAHEDA------VQGIANEDAVHGVAKEVAAHGVANEDP------VQGVANE 1122 A A G +G+ G +V G ED QG + Sbjct: 470 AGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQ 529 Query: 1123 DAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGI 1182 V G G + +G+ G+ + G A G A E QG Sbjct: 530 PGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGA 589 Query: 1183 AHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVA 1242 QG+ G + GV E A + P RG E + G A Sbjct: 590 PGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPG------A 643 Query: 1243 DGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKE 1302 G+ G G S G QG+ E GIA +G E Sbjct: 644 QGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGE 703 Query: 1303 DPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDI 1362 +G +D +G+ + G A + +G G A A G E Sbjct: 704 KGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGP 763 Query: 1363 ANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAV 1422 A G + +G E +G A QG + QG +G Sbjct: 764 AGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP 823 Query: 1423 QGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE 1482 G A G ++G G + +D +G + G A E + G A Sbjct: 824 PGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGP 883 Query: 1483 VAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGI 1542 G +D P +G+A + G+ + G G + A G Sbjct: 884 PGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGA 943 Query: 1543 ANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDA 1602 + + G + G E G D G D V + A+ P A Sbjct: 944 SGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPG---RDGAAGVKGDRGETGAVGAPGA 1000 Query: 1603 AHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAN 1662 + G A QG E A G G QG Sbjct: 1001 P-------------GPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRG 1047 Query: 1663 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQG 1722 + +G A E +G+ G+ G + + G A +G V Sbjct: 1048 D---KGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPV---- 1100 Query: 1723 VAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIA 1760 G + +D A+GI + G G A Sbjct: 1101 --------GPSGKDGANGIPGPIGPPGPRGRSGETGPA 1130 Score = 115 bits (287), Expect = 7e-25 Identities = 197/1028 (19%), Positives = 277/1028 (26%), Gaps = 61/1028 (5%) Query: 65 AHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVAN 124 A G + GV +G D A G A G + G + +G+ Sbjct: 205 ARGFPGTPGLPGVKGH---RGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPG 261 Query: 125 EDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQD 184 E G A +G + G G A G E + AQ Sbjct: 262 ERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQG 321 Query: 185 IANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVE 244 E G G D G G+A G QG + Sbjct: 322 PRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLG 381 Query: 245 VQGVAHEDAVQGIANEDAAHGITNEV---AAHGIANEDAAQGIANEDAAQGIAHEDAVQG 301 +G E + G E G A G A E+ +G E G +G Sbjct: 382 PKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERG 441 Query: 302 IANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDA 361 G G E +A P A+G G+ A G+ Sbjct: 442 APGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPG---ARGLTGRPG 498 Query: 362 AHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIA 421 G +V G ED G G G A+G Sbjct: 499 DAGPQGKVGPSGAPGEDGRPGPPGPQGARG-------------QPGVMGFPGPKGANGEP 545 Query: 422 NEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVH 481 + +G+ G+ +D G A G A E QG QG+ Sbjct: 546 GKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPP 605 Query: 482 GVAKEVAAHGVANKDAAHAIAKPDAARGIANE---VAAQGIATEDVADGIANEDAVHGVA 538 G + GV + A + P RG E AQG+ G D G + Sbjct: 606 GEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGAS 665 Query: 539 NEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVH 598 G + A GIA +G E +G +D G+ + Sbjct: 666 GPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPP 725 Query: 599 GVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGV--VA 656 G A + +G G A A G E G A G + G A Sbjct: 726 GPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEA 785 Query: 657 NEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQ 716 + P G G+ A+G A G A G Sbjct: 786 GQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFP---GAAGRVGPPGSN 842 Query: 717 GIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEV 776 G G + +D +G + G A E G A +G +D G Sbjct: 843 GNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPP 902 Query: 777 EVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVA 836 QG+A + + G+ + G G + A G + + G + G A Sbjct: 903 GPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPA 962 Query: 837 NEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVA 896 E +G A G D GV + G V A P A +G Sbjct: 963 GEPGREG---SPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDR 1019 Query: 897 NEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHG 956 E AQG G A GI + + +G A E G Sbjct: 1020 GEAGAQGPMGPSGPAG-----ARGIQGPQGPR---------------GDKGEAGEPGERG 1059 Query: 957 VANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDA 1016 + G+ G + + G A +G V G + KD GI Sbjct: 1060 LKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPV---GPSGKDGANGIPGPIG 1116 Query: 1017 AHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAH-GISKE----DAVQGIANEDAA 1071 G G A G G +++A G+ D +Q + + AA Sbjct: 1117 PPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAA 1176 Query: 1072 QGIANEDA 1079 G+ DA Sbjct: 1177 GGLRQHDA 1184 Score = 114 bits (284), Expect = 1e-24 Identities = 203/1050 (19%), Positives = 280/1050 (26%), Gaps = 75/1050 (7%) Query: 1253 GVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANED 1312 G E A G D G G G+ AAQ D G A Sbjct: 69 GDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLG 128 Query: 1313 PIQGVANEVEVQGV---AHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQ 1369 +QG + +G A QG G G +D Sbjct: 129 VMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEA 188 Query: 1370 GISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANED 1429 G + +G A+G + GV G+ +G A V+G + Sbjct: 189 GKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDG---AKGEAGAPGVKGESGSP 245 Query: 1430 AAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVA 1489 +G + G+ E G A A+G + G G A G Sbjct: 246 GENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAK 305 Query: 1490 NEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVH 1549 E P+ A+G E T G A G D G A GIA Sbjct: 306 GEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFP 365 Query: 1550 GVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVV--ANEDAAQAIAKPDAAHGIA 1607 G QG + G E + G E A A A + G Sbjct: 366 GPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGAR 425 Query: 1608 NEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQ 1667 E +G G G E G+A A G Sbjct: 426 GEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEP 485 Query: 1668 GIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDP---------------VQGVANEDAVQ 1712 G+ +G+ G +V G ED V G Sbjct: 486 GLP---GARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGAN 542 Query: 1713 GVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANED 1772 G + +G+ ++G+ +D G G A E QG QG+ Sbjct: 543 GEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPP 602 Query: 1773 AVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANE---VAAQGIATEDVADGIPNEDAAH 1829 + GV E A + P RG E AQG+ G P D Sbjct: 603 GPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPK 662 Query: 1830 GVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANED 1889 G + G +QG+ E A GIA +G E +G +D +G+ Sbjct: 663 GASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPI 722 Query: 1890 AAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIA 1949 G A + +G A A G E G A G A G Sbjct: 723 GPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPA------GFAGPPGADG-- 774 Query: 1950 NEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAH 2009 + A+G E G A QG + QG +G G A Sbjct: 775 -QPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAA 833 Query: 2010 AIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEG 2069 P + G G + +D G + G A E Q A P G + Sbjct: 834 GRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGD- 892 Query: 2070 IATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAA 2129 D G Q +A Q G+ + +G G + A Sbjct: 893 ------------DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGA 940 Query: 2130 HGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANE 2189 G + + G G A E +G D G +D G+ + Sbjct: 941 PGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPG------------RDGAAGVKGD 988 Query: 2190 DAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGV---ANEVAVHGVANEDAA 2246 +G V A G + G A QG E AQG + G+ Sbjct: 989 ---RGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGP 1045 Query: 2247 RHMAKEDAAQGIANEDAAHGIANEDAVHGI 2276 R +G A E G+ G+ Sbjct: 1046 R------GDKGEAGEPGERGLKGHRGFTGL 1069 Score = 110 bits (274), Expect = 2e-23 Identities = 227/1147 (19%), Positives = 304/1147 (26%), Gaps = 102/1147 (8%) Query: 689 QGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE 748 QG A E +G G E G D G G G+ Sbjct: 56 QGPAGEQGPRG------DRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGN 109 Query: 749 VAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGV 808 AA D G A V+QG + +G G A G G Sbjct: 110 FAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRG------PPGPAGAPGPQGFQGNPGEPGE 163 Query: 809 ANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEAL 868 G G +D G + +G A G + GV Sbjct: 164 PGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGY 223 Query: 869 HGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQ 928 G+ +G E A G+ E + G +G + Sbjct: 224 PGL---------------------DGAKGEAGAPGVKGESGSPG-----ENGSPGPMGPR 257 Query: 929 AIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVA---AQGVANEDAVHGVA 985 + + T A G D G A G A A G E G Sbjct: 258 GLPGERGR---TGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGAR 314 Query: 986 NEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQ 1045 + QG E G G D G A GIA G Q Sbjct: 315 GPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQ 374 Query: 1046 GIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEV 1105 G + G + E + G E +G QG G A E+ G E Sbjct: 375 GATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQG------APGPAGEEGKRGARGEP 428 Query: 1106 AAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIA 1165 G +G G +G E G+A A+G G+ Sbjct: 429 GGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLP 488 Query: 1166 NEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAR 1225 G + QG +V G ED P AR Sbjct: 489 GARGLTGRPGDAGPQG---------------------KVGPSGAPGEDGRPGPPGPQGAR 527 Query: 1226 GIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKED 1285 G + G A+G + G+ G+ +D G A G A E Sbjct: 528 G---QPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGER 584 Query: 1286 AVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANE---DAAH 1342 QG QG+ G + QGV E G+ +G E A Sbjct: 585 GEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQ 644 Query: 1343 GIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANED 1402 G+ G D + + G +QG+ E A GIA +G E Sbjct: 645 GLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEK 704 Query: 1403 AVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIA 1462 +G + +G+ G A A+G EV G A A+G E G Sbjct: 705 GPEGAPGKDGGRGLTGPIGPPGPA---GANGEKGEVGPPGPAGSAGARGAPGERGETGPP 761 Query: 1463 HEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVAD 1522 G D G E G + A P A G G A Sbjct: 762 GPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQ 821 Query: 1523 GIANEDAAHGVANEV---AAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVV 1579 G G A V + G G + +D +G + G A E +QG Sbjct: 822 GPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPA 881 Query: 1580 NEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAA 1639 +D P G+A + + + +G G + A Sbjct: 882 GPPG-EKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGA 940 Query: 1640 HGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE---VAAHGV 1696 G S + G G A E +G D G V G E V A G Sbjct: 941 PGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGA 1000 Query: 1697 ANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAA 1756 G A QG E QG G + A GI G Sbjct: 1001 PGPPGSPGPAGPTGKQGDRGEAGAQG------PMGPSGPAGARGIQGPQGPRG------D 1048 Query: 1757 QGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATE 1816 +G A E +G+ + G + + A A P RG V G + Sbjct: 1049 KGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSG---K 1105 Query: 1817 DVADGIP 1823 D A+GIP Sbjct: 1106 DGANGIP 1112 Score = 108 bits (269), Expect = 8e-23 Identities = 222/1123 (19%), Positives = 299/1123 (26%), Gaps = 69/1123 (6%) Query: 75 QGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANE 134 +G E A G D G G G+ AAQ D G A Sbjct: 68 RGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQL 127 Query: 135 DAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQGI 194 +QG +G A G QG E ++ + G Sbjct: 128 GVMQGPMGPMGPRGPPGPAGAPG---PQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGD 184 Query: 195 SKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAV 254 E G A E G G V+G + G E GV E Sbjct: 185 DGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGS 244 Query: 255 QGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE 314 G +G + G+ E G A A+G + G G Sbjct: 245 PG------ENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGF 298 Query: 315 VAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKEVTAHGV 374 A G E P+ A G E T G A G D G A G+ Sbjct: 299 PGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGI 358 Query: 375 ANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVA 434 A G G P G E G E +G Sbjct: 359 AGAPGFPGPRGPPGPQGATG----------PLGPKGQTGEPGIAGFKGEQGPKGEPGPAG 408 Query: 435 AHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVAN 494 G G A E+ +G E G +G G G Sbjct: 409 PQG------APGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPG 462 Query: 495 KDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHA 554 + +A P A G G+ A G+ G +V G ED Sbjct: 463 ERGPSGLAGPKGANGDPGRPGEPGLPG---ARGLTGRPGDAGPQGKVGPSGAPGEDGRPG 519 Query: 555 IAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDA 614 P A G + G A+G + G+ + G+ +D G A Sbjct: 520 PPGPQGARG---QPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPG 576 Query: 615 VHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIA 674 G A E QG G+ G + GV E A + P G Sbjct: 577 PAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGV-PGEAGAPGLVGPRGERGFP 635 Query: 675 NE---VAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHED 731 E A G+ G D +G + G +QG+ E A GIA Sbjct: 636 GERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPK 695 Query: 732 AVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIA 791 +G E G + G+ G A + G EV G A G A Sbjct: 696 GDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGAN---GEKGEVGPPGPA------GSA 746 Query: 792 NEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAH 851 A G E G A G + A+G E G A QG + Sbjct: 747 GARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQ 806 Query: 852 GVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVAD 911 G T +G + G AA + P + G G + +D Sbjct: 807 GPTGVTGPKGARGAQGPPGATGFPGAAGRVGPP------GSNGNPGPPGPPGPSGKDGPK 860 Query: 912 GIAKDAAH-GITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEV 970 G D+ G E Q A +D G G+A + G+ + Sbjct: 861 GARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQR 920 Query: 971 AAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIA 1030 +G G + G + + G + G A E G A G Sbjct: 921 GERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREG---SPGADGPP 977 Query: 1031 NEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGI------A 1084 D A G+ + +G V A G G A QG E AQG A Sbjct: 978 GRDGAAGVKGD---RGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPA 1034 Query: 1085 HEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQ 1144 +QG G A E G+ G+ G + + G A + Sbjct: 1035 GARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPR 1094 Query: 1145 GI------ANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQG 1181 G + +D A+GI + G G A G Sbjct: 1095 GPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPG 1137 Score = 59.7 bits (143), Expect = 3e-08 Identities = 91/471 (19%), Positives = 129/471 (27%), Gaps = 25/471 (5%) Query: 63 DAAHGITNEDAVQGVANEVAAQGVANEDAAHGVA---------NEVAAHGVANEDAAQGV 113 D G + G QG+ E A G+A E G +D +G+ Sbjct: 659 DGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGL 718 Query: 114 ANEVAAQGVANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAA 173 + G A + +G G A G E G A G + A Sbjct: 719 TGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGA 778 Query: 174 QDIAKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANE 233 + E + A QG S QG +G G G Sbjct: 779 KGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAGRVGP 838 Query: 234 DAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGI 293 G G + +D +G + G E G A +G +D G Sbjct: 839 PGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGA 898 Query: 294 AHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVA 353 QG+A + + G+ + G A G + + G Sbjct: 899 EGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGL 958 Query: 354 DGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIAN 413 G A E G A G D GV + G V A P + G A Sbjct: 959 TGPAGEPGREG---SPGADGPPGRDGAAGVKGDRGETGAV----GAPGAPGPPGSPGPAG 1011 Query: 414 EVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQG 473 G E AQG + G + +QG +G A E +G+ G Sbjct: 1012 PTGKQGDRGEAGAQG---PMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTG 1068 Query: 474 IANEDAVHGVAKEVAAHGVANKDAAHAIAKP------DAARGIANEVAAQG 518 + G + + A G A P D A GI + G Sbjct: 1069 LQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPG 1119 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 114 bits (285), Expect = 1e-24 Identities = 195/1014 (19%), Positives = 268/1014 (26%), Gaps = 27/1014 (2%) Query: 487 VAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGV 546 ++ G + P A G G E A G G + G Sbjct: 175 ISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGE 234 Query: 547 ANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAV 606 A + P G T G+ G + D A G A G Sbjct: 235 AGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGE 294 Query: 607 QGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAK 666 G + G+ E G A G D G G A+ Sbjct: 295 NGAPGQMGPRGLPGERGRPGAPGPAGARG---NDGATGAAGPPGPTGPAGPPGFPGAV-- 349 Query: 667 PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG 726 G E G + QG+ E G A G D G + A G Sbjct: 350 -----GAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPG 404 Query: 727 IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDA 786 IA G G G + E G + +G V VQG Sbjct: 405 IAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQG------ 458 Query: 787 VQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAK 846 G A E+ G E G+ +G G G A E + G A Sbjct: 459 PPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAG 518 Query: 847 EVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIAT 906 + G G+ + L G + P A G A+G A Sbjct: 519 PKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQA- 577 Query: 907 EDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGV 966 V A G + + + A +D G G A E QG Sbjct: 578 -GVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGP 636 Query: 967 ANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAA 1026 A QG+ G A + QGV ++ G + +G E G Sbjct: 637 AGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQG------P 690 Query: 1027 HGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHE 1086 G A A G D A+G A A G +QG+ E A G+ +G A Sbjct: 691 PGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGP 750 Query: 1087 DAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGI 1146 G +D V G+ + G A +G + G G E G Sbjct: 751 KGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGP 810 Query: 1147 ANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAA 1206 A G + A G + A+G A G A G G Sbjct: 811 AGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGP 870 Query: 1207 HGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKE 1266 G A P G A G A ++ G E G EV G Sbjct: 871 PGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGP 930 Query: 1267 DAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGV 1326 +G D G QGIA + G+ + +G + G + E QG Sbjct: 931 AGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPG---LPGPSGEPGKQGP 987 Query: 1327 AHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAA 1386 + +G G+A G A+ D + G + G A A Sbjct: 988 SGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGA 1047 Query: 1387 QGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANE 1446 G G A + +G G +G A G E G Sbjct: 1048 PGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGI 1107 Query: 1447 DAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKP 1500 +G + G QG + G + G +D + + P Sbjct: 1108 KGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGP 1161 Score = 104 bits (260), Expect = 9e-22 Identities = 168/807 (20%), Positives = 223/807 (27%), Gaps = 29/807 (3%) Query: 67 GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126 G+ E G A+G A G G A G E QG + Sbjct: 305 GLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSE 364 Query: 127 AVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIA 186 QGV E G A G D G + A GIA Q Sbjct: 365 GPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPG 424 Query: 187 NEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQ---GVANEDPVQGVANEDAVQGVANEV 243 +G S E G + A+G VQ G A E+ +G E G+ Sbjct: 425 GPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPP 484 Query: 244 EVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIA 303 +G +G D G G +G E G A +G+ Sbjct: 485 GERG---GPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLT 541 Query: 304 NEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAH 363 G + G A +D P A G + G A G + Sbjct: 542 GSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARG---QAGVMGFPGPKGAAGEPGKAGER 598 Query: 364 GVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANE 423 GV A G A +D G G A E Q A G+ G A + Sbjct: 599 GVPGPPGAVGPAGKDGEAGAQGPPGPAG-PAGERGEQGPAGSPGFQGLPGPAGPPGEAGK 657 Query: 424 DAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGV 483 QG+ ++ A G S +G E QG G A G D G Sbjct: 658 PGEQGVPGDLGAPGPSGARGERGFPGERGVQG------PPGPAGPRGANGAPGNDGAKGD 711 Query: 484 AKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAA 543 A A G + A G+ +G A ADG +D V G+ + Sbjct: 712 AGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGP 771 Query: 544 HGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIE 603 G A + P G A +G A G E G A G + Sbjct: 772 PGPAGAPGDKGESGPS---GPAGPTGARG------APGDRGEPGPPGPAGFAGPPGADGQ 822 Query: 604 DAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQA 663 +G + G A G A G +G G AA Sbjct: 823 PGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGR 882 Query: 664 IAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDA 723 + P + G A G A ++ +G E G EV G +G D Sbjct: 883 VGPPGPS-GNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADG 941 Query: 724 AQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAH 783 G QGIA + V G+ + G + G + E QG + +G Sbjct: 942 PAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPG---LPGPSGEPGKQGPSGASGERGPPG 998 Query: 784 EDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQG 843 G+A G A G D + G + G A G G Sbjct: 999 PMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVG 1058 Query: 844 VAKEVTAHGVTNEDAVQGVVNEEALHG 870 A + G T G V G Sbjct: 1059 PAGKSGDRGETGPAGPAGPVGPVGARG 1085 Score = 101 bits (252), Expect = 8e-21 Identities = 199/1033 (19%), Positives = 269/1033 (26%), Gaps = 63/1033 (6%) Query: 1221 PDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQG 1280 P RG+ A G G E A G G ++ G A + G Sbjct: 183 PSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPG 242 Query: 1281 IAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDA 1340 QG G+ +G + D +G A +G G + Sbjct: 243 ERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMG 302 Query: 1341 AHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVAN 1400 G+ E G A+ D A G + G A G Sbjct: 303 PRGLPGERGRPGAPGPAGAR---GNDGATGAAGPPGPTGPAGPPGFPGAV---------- 349 Query: 1401 EDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQG 1460 G E QG + QG+ E G A G D G + A G Sbjct: 350 -----GAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPG 404 Query: 1461 IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDV 1520 IA G G G + E A A+G V QG Sbjct: 405 IAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQG------ 458 Query: 1521 ADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVN 1580 G A E+ G E G+ G G G A E G Sbjct: 459 PPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAG 518 Query: 1581 EDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAH 1640 E A A G+ + K G A QD G A Sbjct: 519 PKGS----PGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGAR 574 Query: 1641 GISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANED 1700 G + V G A G + +G+ G A +D G G A E Sbjct: 575 G---QAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGER 631 Query: 1701 PVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIA 1760 QG A QG+ G A + QG+ + A G + G E QG Sbjct: 632 GEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPP 691 Query: 1761 HEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVAD 1820 +G A+G D A A A G QG+ E A Sbjct: 692 GPAGPRG---------------ANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAA 736 Query: 1821 GIPNEDAAHGVANEVAAHGISKEDAVQGIA------NEDAAQGIAKEDPIQGVANEVEVQ 1874 G+P G A A G +D V+G+ A G E G A + Sbjct: 737 GLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGAR 796 Query: 1875 GV---AHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIA 1931 G E G A G + A+G + A+ A G + G Sbjct: 797 GAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNV 856 Query: 1932 NQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQ 1991 A+G G A G G A G A ++ +G E Sbjct: 857 GAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPA 916 Query: 1992 GIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANED 2051 G E G D G QGIA + G+ + G Sbjct: 917 GRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLP 976 Query: 2052 AAQAIAKPDAAHGIANE-----GIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGIT 2106 G + E + +A E +G E + +D + G Sbjct: 977 GPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPG---RDGSPGAK 1033 Query: 2107 KEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQ 2166 + G A G G A + G G V A+G A + Sbjct: 1034 GDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPR 1093 Query: 2167 GVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANED 2226 G E QG +G + G G + G + G +D Sbjct: 1094 GDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKD 1153 Query: 2227 AAQGVANEVAVHG 2239 G+ + G Sbjct: 1154 GLNGLPGPIGPPG 1166 Score = 101 bits (252), Expect = 8e-21 Identities = 186/923 (20%), Positives = 244/923 (26%), Gaps = 33/923 (3%) Query: 406 DAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGI 465 D A G A G G ++ G+ E G A+G D A G Sbjct: 274 DGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARG---NDGATGA 330 Query: 466 AHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVA 525 A G A G V A G A P RG E G A Sbjct: 331 AGPPGPTGPAGPPGFPGA---VGAKGEAGPQGPRGSEGPQGVRG---EPGPPGPAGAAGP 384 Query: 526 DGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANE 585 G D G A G+A P G +G + E A G + Sbjct: 385 AGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGD 444 Query: 586 DAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGV 645 A G V V G G A E+ G E G+ G E G Sbjct: 445 TGAKGEPGPVGVQGPP------GPAGEEGKRGARGEPGPTGLP------GPPGERGGPGS 492 Query: 646 VNEDALHGVVANEDAAQAIAKPDAA--HGIANEVAAHGIANEDAAQGIANEDAAQGIANE 703 GV + A P A G E G A A+G+ + G + Sbjct: 493 RGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGK 552 Query: 704 VAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGV 763 G + +D G A+G A V G G + GV G Sbjct: 553 TGPPGPAGQDGRPGPPGPPGARGQA---GVMGFPGPKGAAGEPGKAGERGVPGPPGAVGP 609 Query: 764 ANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAA 823 A +D G G A E QG A G+ G A + QGV + A Sbjct: 610 AGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGA 669 Query: 824 QGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAK 883 G + G E QG G G + G ++ A Sbjct: 670 PGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGM 729 Query: 884 PDAAHGIANEGVANEVAAQGIATEDVADGI-AKDAAHGITKEEAAQAIAKQDAAHSITNE 942 P G A G+ +G A ADG KD G+T A + Sbjct: 730 P-GERGAA--GLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGP 786 Query: 943 DAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGI 1002 G A G E G A G + G + +G A G Sbjct: 787 SGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGP 846 Query: 1003 AHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAV 1062 A G A G G A G G A G + ++ Sbjct: 847 AGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGG 906 Query: 1063 QGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANE 1122 +G E G E G +G D G G+A + V G+ + Sbjct: 907 KGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQ 966 Query: 1123 DAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGI 1182 +G + G + E QG + G + G+A G A+G Sbjct: 967 RGERGFPG---LPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGS 1023 Query: 1183 AHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVA 1242 D G + G A A G A RG G A Sbjct: 1024 PGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGA 1083 Query: 1243 DGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKE 1302 G A G E G +G + G QG + G Sbjct: 1084 RGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGP 1143 Query: 1303 DPVQGVANEDPIQGVANEVEVQG 1325 G +D + G+ + G Sbjct: 1144 PGSAGAPGKDGLNGLPGPIGPPG 1166 Score = 101 bits (252), Expect = 8e-21 Identities = 187/884 (21%), Positives = 241/884 (27%), Gaps = 61/884 (6%) Query: 956 GVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANED 1015 G D A G A G A G G E QG + QG+ E Sbjct: 320 GARGNDGATGAAGPPGPTGPAGPPGFPGAV------GAKGEAGPQGPRGSEGPQGVRGEP 373 Query: 1016 AAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIA 1075 G A G D G + A GIA G QG +G + Sbjct: 374 GPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNS 433 Query: 1076 NEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQ 1135 E A G + +G V G G A E+ +G E G+ + Sbjct: 434 GEPGAPGSKGDTGAKGEPGPVGVQGPP------GPAGEEGKRGARGEPGPTGLPGPPGER 487 Query: 1136 GVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 1195 G G G A E + G A + G A G+ +G+ Sbjct: 488 GGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLP---GAKGLTGSP 544 Query: 1196 AVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVA 1255 G + G A +D P ARG A + G G A E G Sbjct: 545 GSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPP 604 Query: 1256 NEVAAHGISKEDAVQGI------ANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVA 1309 V G E QG A E QG A QG+ G A + QGV Sbjct: 605 GAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVP 664 Query: 1310 NEDPIQGVANEVEVQGVAHEDAVQGI---ANEDAAHGIANEDAAQGIANEDAAQDIANED 1366 + G + +G E VQG A A+G D A+G A A Sbjct: 665 GDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAP 724 Query: 1367 AAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIA 1426 QG+ E G+ +G A G +D V+G+ + G A G Sbjct: 725 GLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPA---GAPGDK 781 Query: 1427 NEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAH 1486 E G A A G A G E G A G + G + A Sbjct: 782 GESGPSGPAGPTGARG------APGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAK 835 Query: 1487 GVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEV 1546 G A A P G +G G A G G A Sbjct: 836 GDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPP 895 Query: 1547 AVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGI 1606 G A ++ +G E G E G A E + P A G Sbjct: 896 GPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGP-------AGEKGSPGADGPAGAPG- 947 Query: 1607 ANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAA 1666 QGIA Q G+ + G + G + E QG + Sbjct: 948 -----------TPGPQGIAGQRGVVGLPGQRGERGF---PGLPGPSGEPGKQGPSGASGE 993 Query: 1667 QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHE 1726 +G G+A G A G D G + G A G Sbjct: 994 RGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGA 1053 Query: 1727 DAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGV 1786 G A + G T G A+G A +G E E G+ Sbjct: 1054 PGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETG------EQGDRGI 1107 Query: 1787 ANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHG 1830 + P G E G + G P A G Sbjct: 1108 KGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPG 1151 Score = 98.6 bits (244), Expect = 6e-20 Identities = 191/952 (20%), Positives = 258/952 (27%), Gaps = 75/952 (7%) Query: 608 GVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKP 667 G +D G +G A G+ + G+ G+ D A+ A P Sbjct: 227 GKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGL----DGAKGDAGP 282 Query: 668 DAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGI 727 G +G + +G+ E G A G D G A G Sbjct: 283 AGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARG---NDGATGAAGPPGPTGP 339 Query: 728 AHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAV 787 A G G E G + QGV E G A G D Sbjct: 340 AGPPGFPGAV------GAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQ 393 Query: 788 QGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKE 847 G + A GIA G QG +G + E G + A+G Sbjct: 394 PGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGP 453 Query: 848 VTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATE 907 V G G EE G P G + G Sbjct: 454 VGVQGPP------GPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPG---------- 497 Query: 908 DVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVA 967 ADG+A G E + A +G E G A A+G+ Sbjct: 498 --ADGVA--GPKGPAGERGSPGPA------------GPKGSPGEAGRPGEAGLPGAKGLT 541 Query: 968 NEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAH 1027 + G + G A +D G +G A + G A G + Sbjct: 542 GSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQA---GVMGFPGPKGAAGEPGKAGER 598 Query: 1028 GIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHED 1087 G+ A G A +D G G + E QG A QG+ G A + Sbjct: 599 GVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKP 658 Query: 1088 AVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIA 1147 QG+ + G + G E VQG +G G D +G A Sbjct: 659 GEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGA------NGAPGNDGAKGDA 712 Query: 1148 NEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAH 1207 A G G+ E A G+ +G A G +D V G+ + Sbjct: 713 GAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPP 772 Query: 1208 GVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKED 1267 G A + P G A A+G A G E G A G + Sbjct: 773 GPAGAPGDKGESGPS---GPAGPTGARG------APGDRGEPGPPGPAGFAGPPGADGQP 823 Query: 1268 AVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVA 1327 +G + A+G A G A G +G G G Sbjct: 824 GAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRV 883 Query: 1328 HEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQ 1387 G A G A ++ +G E E G G A E + Sbjct: 884 GPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPG------PPGPAGEKGSP 937 Query: 1388 GIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANED 1447 G D G QG+A + V G+ + +G G + G + E Sbjct: 938 GA---DGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGER 994 Query: 1448 AAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIA 1507 G G E +G + G A G E A P A G Sbjct: 995 GPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGP---AGPPGAPGAP 1051 Query: 1508 NEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQG 1559 G A + G G V A+G A G E QG Sbjct: 1052 GAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQG 1103 Score = 98.2 bits (243), Expect = 8e-20 Identities = 206/1038 (19%), Positives = 278/1038 (26%), Gaps = 61/1038 (5%) Query: 75 QGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANE 134 +G+ A G G E A G G + G A + G Sbjct: 187 RGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGP 246 Query: 135 DAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQGI 194 QG G+ G + D A+G A + + +G+ Sbjct: 247 PGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGL 306 Query: 195 SKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVAN---EVEVQGVAHE 251 E G A+G D G A G A G E QG Sbjct: 307 PGERGRPGAPGPAGARG---NDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGS 363 Query: 252 DAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 311 + QG+ E G G D G + A GIA G G Sbjct: 364 EGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGP 423 Query: 312 AKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKEVTA 371 G + E A A G V QG G A E+ G E Sbjct: 424 GGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQG------PPGPAGEEGKRGARGEPGP 477 Query: 372 HGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIAN 431 G+ +G G A +A P G A E + G A + G A Sbjct: 478 TGLPGPPGERGGPGSRGFPG-------ADGVAGPK---GPAGERGSPGPAGPKGSPGEAG 527 Query: 432 EVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHG 491 G+ +G+ + G + G A +D G G A + G Sbjct: 528 RPGEAGLP---GAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPG 584 Query: 492 VANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDA 551 K AA K RG+ A G A +D G G A E G A Sbjct: 585 P--KGAAGEPGKA-GERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPG 641 Query: 552 AHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVAN 611 + P G A + QG+ + A G + G E V G G A Sbjct: 642 FQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPP------GPAG 695 Query: 612 EDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAH 671 +G D A+G A A G +QG+ E A + P Sbjct: 696 PRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGM----------PGERGAAGLPGPKGDR 745 Query: 672 GIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHED 731 G A A G +D +G+ G A A G E G A A+G Sbjct: 746 GDAGPKGADGSPGKDGVRGLTGPIGPPGPAG---APGDKGESGPSGPAGPTGARG----- 797 Query: 732 AVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIA 791 G E G A G + +G + +G A G A G Sbjct: 798 -APGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNV 856 Query: 792 NEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAH 851 A G G A G G A G A ++ +G E Sbjct: 857 GAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPA 916 Query: 852 GVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVAD 911 G E G G + A A P +G+A + G+ + Sbjct: 917 GRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGP------QGIAGQRGVVGLPGQRGER 970 Query: 912 GIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVA 971 G G + E Q + G+A G A+G Sbjct: 971 GFP--GLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDG 1028 Query: 972 AQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIAN 1031 + G + G A G G A K +G G V A G A Sbjct: 1029 SPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAG 1088 Query: 1032 EDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQG 1091 +G E QG G S G QG + G G Sbjct: 1089 PQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAG 1148 Query: 1092 IANEDAVHGVAKEVAAHG 1109 +D ++G+ + G Sbjct: 1149 APGKDGLNGLPGPIGPPG 1166 Score = 96.3 bits (238), Expect = 3e-19 Identities = 160/766 (20%), Positives = 209/766 (27%), Gaps = 15/766 (1%) Query: 65 AHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVAN 124 A G E QG QGV E G A G D G A G+A Sbjct: 348 AVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAG 407 Query: 125 EDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDI---AKEDA 181 G QG +G + E A G + A+G Q A E+ Sbjct: 408 APGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEG 467 Query: 182 AQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVAN 241 + E G+ +G ++G D V G +G +G Sbjct: 468 KRGARGEPGPTGLPGPPGERG---GPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPG 524 Query: 242 EVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQG 301 E G A +G+ + G + G A +D G A+G A V G Sbjct: 525 EAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQA---GVMG 581 Query: 302 IANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDA 361 G + GV A A D G G A E G A Sbjct: 582 FPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPG 641 Query: 362 AHGVAKEVTAHGVANEDAVQGVVNEDALHGV--VANEDAAQAIAKPDAAHGIANEVAAHG 419 G+ G A + QGV + G E G A A+G Sbjct: 642 FQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANG 701 Query: 420 IANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDA 479 D A+G A A G +QG+ E A G+ +G A G +D Sbjct: 702 APGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDG 761 Query: 480 VHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVAN 539 V G+ + G A + P G A G E G A G Sbjct: 762 VRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADG 821 Query: 540 EVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHG 599 + A G + A A P G A G A G G G Sbjct: 822 QPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAG 881 Query: 600 VAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANED 659 G A G A ++ +G E G E G G + Sbjct: 882 RVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADG 941 Query: 660 AAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIA 719 A A P GIA + G+ + +G G + G S E G Sbjct: 942 PAGAPGTP-GPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPM 1000 Query: 720 NEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQ 779 G E +G + G A G E G G V Sbjct: 1001 GPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPV--- 1057 Query: 780 GIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQG 825 G A + +G G V A G A +G E QG Sbjct: 1058 GPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQG 1103 Score = 92.8 bits (229), Expect = 4e-18 Identities = 145/670 (21%), Positives = 192/670 (28%), Gaps = 40/670 (5%) Query: 1619 DAAQGIANQDAAQGIANEVA---AHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAV 1675 D A G A G A A G E QG + QG+ E G A Sbjct: 325 DGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGP 384 Query: 1676 QGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANE 1735 G D G A G+A G QG +G + E G + Sbjct: 385 AGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGD 444 Query: 1736 DAAHGITNEVAAHGI---ANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAA 1792 A G V G A E+ +G E G+ E G A Sbjct: 445 TGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPG------ERGGPGSRGFPGA 498 Query: 1793 HAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANE 1852 +A P +G A E + G A G P E G A A G++ G + Sbjct: 499 DGVAGP---KGPAGERGSPGPAGPK---GSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGK 552 Query: 1853 DAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDI 1912 G A +D G +G A V G A G + +G+ A Sbjct: 553 TGPPGPAGQDGRPGPPGPPGARGQA---GVMGFPGPKGAAGEPGKAGERGVPGPPGAVGP 609 Query: 1913 ANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAA 1972 A +D G G A + QG A QG+ G A + G+ + A Sbjct: 610 AGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGA 669 Query: 1973 QGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATE 2032 G + +G E VQG G A A+ D A+G A A G Sbjct: 670 PGPSGARGERGFPGERGVQGPP------GPAGPRGANGAPGNDGAKGDAGAPGAPGSQGA 723 Query: 2033 DVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEA 2092 G+ E A G+ + A P A G + D V+G+T Sbjct: 724 PGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGK-------------DGVRGLTGPIG 770 Query: 2093 AQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVAN 2152 A G + G T A G E G A G + A+G Sbjct: 771 PPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPG 830 Query: 2153 EVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQG 2212 + A+G A G A G +G G A G G Sbjct: 831 DAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSG 890 Query: 2213 VANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDA 2272 A G A ++ +G E G E +G D G Sbjct: 891 NAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPG 950 Query: 2273 VHGIANEDAV 2282 GIA + V Sbjct: 951 PQGIAGQRGV 960 Score = 90.9 bits (224), Expect = 1e-17 Identities = 174/872 (19%), Positives = 237/872 (27%), Gaps = 58/872 (6%) Query: 1415 GVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 1474 G QG E G + + G G E G E G Sbjct: 194 GAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGAR 253 Query: 1475 AVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVA 1534 + G A G+ + D A+G A +G +G + G+ Sbjct: 254 GLPGTA------GLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLP 307 Query: 1535 NEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNE--DALHSVVANED 1592 E G G D G G A G V +A + Sbjct: 308 GERGRPGAPGPAGARG---NDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSE 364 Query: 1593 AAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIA 1652 Q + G A D G + A GIA G QG Sbjct: 365 GPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPG 424 Query: 1653 NEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV---AKEVAAHGVANEDPVQGVANED 1709 +G + E A G + +G V G A E G E G+ Sbjct: 425 GPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPP 484 Query: 1710 AVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIA 1769 +G +G D V G G G E G A +G+ Sbjct: 485 GERGGPGS---RGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLT 541 Query: 1770 NEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVA------AQGIATEDVADGIP 1823 + G A +D P ARG A + A G + G+P Sbjct: 542 GSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVP 601 Query: 1824 NEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQ 1883 A G A + G G A E QG A QG+ G A + Q Sbjct: 602 GPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQ 661 Query: 1884 GIANEDAAHGIANEDAAQGIANEDAAQDI---ANEDAAQGISKEDAVQGIANQDAAQGIA 1940 G+ + A G + +G E Q A A G D +G A A G Sbjct: 662 GVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQ 721 Query: 1941 KEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVH 2000 +QG+ E A G+ G A A G +D +G+ G A Sbjct: 722 GAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDK 781 Query: 2001 GVANEDAAHAIAKPDAARGIANE------VAAQGIATEDVADGIANEDAAHGVANEDAAQ 2054 G E A P ARG + G A ADG + A G + A+ Sbjct: 782 G---ESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADG---QPGAKGEPGDAGAK 835 Query: 2055 AIAKPDAAHG-------IANEGIATEDVADGIAED-------AVQGITNEEAAQAIAKQD 2100 A P G I N G A G A G A Sbjct: 836 GDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPP 895 Query: 2101 AAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVA 2160 G ++ +G E G E G G D G QG+A Sbjct: 896 GPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIA 955 Query: 2161 NEDAVQGVANEVEVQGI------AHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVA 2214 + V G+ + +G + + QG + +G + G+A G Sbjct: 956 GQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGRE 1015 Query: 2215 NEVAAQGVANEDAAQGVANEVAVHGVANEDAA 2246 A+G D + G + G A A Sbjct: 1016 GAPGAEGSPGRDGSPGAKGDRGETGPAGPPGA 1047 Score = 89.7 bits (221), Expect = 3e-17 Identities = 153/786 (19%), Positives = 215/786 (27%), Gaps = 47/786 (5%) Query: 1500 PDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQG 1559 P ARG+ G+ G + D A G A +G +G + +G Sbjct: 249 PQGARGLPGTAGLPGMKGHR---GFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRG 305 Query: 1560 VVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVA---AHSIA 1616 + E G +G D A A P G A A Sbjct: 306 LPGERGRPGAPGPAGARG-------------NDGATGAAGPPGPTGPAGPPGFPGAVGAK 352 Query: 1617 NKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQ 1676 + QG + QG+ E G + G D G + A GIA Sbjct: 353 GEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFP 412 Query: 1677 GIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGV---AHEDAVQGIA 1733 G G G + E G + +G V VQG A E+ +G Sbjct: 413 GARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGAR 472 Query: 1734 NEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAH 1793 E G+ G ++G D V G G E Sbjct: 473 GEPGPTGLPGPPGERG---GPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRP 529 Query: 1794 AIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANED 1853 A A+G+ + G + G +D G A G + V G Sbjct: 530 GEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARG---QAGVMGFPGPK 586 Query: 1854 AAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIA 1913 A G + +GV G A +D G G A E QG A Q + Sbjct: 587 GAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLP 646 Query: 1914 NEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQ 1973 G + + QG+ A G + +G E QG G A A Sbjct: 647 GPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQG------PPGPAGPRGAN 700 Query: 1974 GIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATED 2033 G D A+G A G + G+ E A + P RG A A G +D Sbjct: 701 GAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKD 760 Query: 2034 VADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAA 2093 G+ G A + + P G A D +G Sbjct: 761 GVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGD----------RGEPGPPGP 810 Query: 2094 QAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANE 2153 A A G + A+G + A+G A G A G A+G Sbjct: 811 AGFAGPPGADG---QPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGS 867 Query: 2154 VAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGV 2213 G G G A G A ++ +G E G E G Sbjct: 868 AGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGP 927 Query: 2214 ANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAV 2273 +G D G G+A + + + +G G + Sbjct: 928 PGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGP 987 Query: 2274 HGIANE 2279 G + E Sbjct: 988 SGASGE 993 Score = 79.0 bits (193), Expect = 5e-14 Identities = 113/504 (22%), Positives = 147/504 (29%), Gaps = 32/504 (6%) Query: 1802 RGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKE 1861 RG + A+G A G P +G ++ G+ E G A+G Sbjct: 268 RGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGA 327 Query: 1862 DPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGI 1921 G G G E G + QG+ E A G Sbjct: 328 TGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGN 387 Query: 1922 SKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAA 1981 D G + A GIA G QG G + E A G + A Sbjct: 388 PGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGA 447 Query: 1982 QGIAHEDAVQGI---ANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGI 2038 +G VQG A E+ G E + P RG G ADG+ Sbjct: 448 KGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPG------ADGV 501 Query: 2039 ANEDAAHGVANEDAAQAIAKPDAAHGIANE-GIATEDVADGIA-EDAVQGITNEEAAQAI 2096 A G A E + A P + G A G A A G+ G + Sbjct: 502 AGPK---GPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGP 558 Query: 2097 AKQDAAHGITKEDAAQGVTNEVA------AQGVANEDAAHGVANEVAAHGVANEDAAQGV 2150 A QD G A+G + A G + GV A G A +D G Sbjct: 559 AGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGA 618 Query: 2151 ANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAA 2210 G A E QG A QG+ G A + QGV ++ A G + Sbjct: 619 QGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGE 678 Query: 2211 QGVANEVAAQ------------GVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGI 2258 +G E Q G D A+G A G + M E A G+ Sbjct: 679 RGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGL 738 Query: 2259 ANEDAAHGIANEDAVHGIANEDAV 2282 G A G +D V Sbjct: 739 PGPKGDRGDAGPKGADGSPGKDGV 762 Score = 75.9 bits (185), Expect = 4e-13 Identities = 135/663 (20%), Positives = 182/663 (27%), Gaps = 45/663 (6%) Query: 1649 QGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANE 1708 +G+ A G G E G G + G A + G Sbjct: 187 RGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGP 246 Query: 1709 DAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGI 1768 QG G+ +G + D A G G G + +G+ Sbjct: 247 PGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGL 306 Query: 1769 ANEDAVHSVAKEVAAHGVANEDAAHAIAKPD-----------AARGIANEVAAQGIATED 1817 E A G N+ A A P A G E QG + Sbjct: 307 PGERGRPGAPGPAGARG--NDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSE 364 Query: 1818 VADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVA 1877 G+ E G A G D G + A GIA G QG Sbjct: 365 GPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPG 424 Query: 1878 HEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDI---ANEDAAQGISKEDAVQGIANQD 1934 +G + E A G + A+G Q A E+ +G E G+ Sbjct: 425 GPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPP 484 Query: 1935 A------AQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHED 1988 ++G D V G +G G E G A A+G+ Sbjct: 485 GERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSP 544 Query: 1989 AVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVA------AQGIATEDVADGIANED 2042 G + G A +D P ARG A + A G + G+ Sbjct: 545 GSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPP 604 Query: 2043 AAHGVANEDAAQAIAKPDAAHGIANE----GIATEDVADGIAEDA----------VQGIT 2088 A G A +D P G A E G A G+ A QG+ Sbjct: 605 GAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVP 664 Query: 2089 NEEAAQAIAKQDAAHGITKEDAAQGVTNEVA---AQGVANEDAAHGVANEVAAHGVANED 2145 + A + G E QG A G D A G A A G Sbjct: 665 GDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAP 724 Query: 2146 AAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVA 2205 QG+ E A G+ +G A G KD ++G+ G A G + Sbjct: 725 GLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGES 784 Query: 2206 NEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAH 2265 G A G E G A G + A+ + A+G A Sbjct: 785 GPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPA 844 Query: 2266 GIA 2268 G A Sbjct: 845 GPA 847 >gi|48762934 alpha 2 type I collagen [Homo sapiens] Length = 1366 Score = 100 bits (248), Expect = 2e-20 Identities = 211/1047 (20%), Positives = 282/1047 (26%), Gaps = 56/1047 (5%) Query: 65 AHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVAN 124 A G QG A E G A G A G A ED G +GV Sbjct: 104 AAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPP---GKAGEDGHPGKPGRPGERGVVG 160 Query: 125 EDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQD 184 +G + G +GI + G+ + A G+ E A Sbjct: 161 PQGARGFPGTPGLPG------FKGIRGHNGLDGLKGQPGAPGVKGEPGA------PGENG 208 Query: 185 IANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVE 244 + A+G+ E G A+G G A G G E+ Sbjct: 209 TPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIG 268 Query: 245 VQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIAN 304 G A G E G++ V G + G G+A + G Sbjct: 269 AVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRG 328 Query: 305 EDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHG 364 G A A G+ E P + G + G A G + E+ G Sbjct: 329 IPGPVGAAGATGARGLVGEPG------PAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRG 382 Query: 365 VAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANED 424 E + G ++G L G D + P + G + G + Sbjct: 383 PNGEAGSAGPPGPPGLRGSPGSRGLPGA----DGRAGVMGPPGSRGASGPAGVRGPNGDA 438 Query: 425 AAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVA 484 G + G+ G A ++ G+ D G +G G Sbjct: 439 GRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPK 498 Query: 485 KEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAH 544 G N D HA G+A A G + A G V G E Sbjct: 499 GPTGDPG-KNGDKGHA--------GLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPP 549 Query: 545 GVAN-------EDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAV 597 G A + KP G+ E G A G E A G + Sbjct: 550 GPPGFQGLPGPSGPAGEVGKP-GERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGS 608 Query: 598 HGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVAN 657 G + G E V G G + G A +G E L G + N Sbjct: 609 RGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGN 668 Query: 658 EDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQG 717 A P A G A G E A G A +G E G + + G Sbjct: 669 PGRDGARGAPGAV-GAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAG 727 Query: 718 IANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVA---NEDVVQGVAN 774 A G E +G E+ V G V A G A + G A + G+ Sbjct: 728 PAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTG 787 Query: 775 EVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAA---QGVANEDA 831 G GI+ G A + G + G E A G A E Sbjct: 788 FPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKG 847 Query: 832 VHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGV--VANEDAAQAIAKPDAAHG 889 G A G G + G E L GV E IA P A G Sbjct: 848 PSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARG 907 Query: 890 ----IANEGVANEVAAQGIATEDVADG-IAKDAAHGITKEEAAQAIAKQDAAHSITNEDA 944 + + GV G DG +D G E A Sbjct: 908 PPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHG 967 Query: 945 AQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAH 1004 G A + G G A V +G + + G E +G ++G Sbjct: 968 PVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNG 1027 Query: 1005 KDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQG 1064 + GIA G V G G A +D G V GI QG Sbjct: 1028 LQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQG 1087 Query: 1065 IANEDAAQGIANEDAAQGIAHEDAVQG 1091 A G G ++ G Sbjct: 1088 PAGPPGPPGPPGPPGVSGGGYDFGYDG 1114 Score = 99.8 bits (247), Expect = 3e-20 Identities = 218/1086 (20%), Positives = 288/1086 (26%), Gaps = 68/1086 (6%) Query: 76 GVANEVAAQ----GVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGV 131 G+ AAQ GV G+ G A QG G + G Sbjct: 72 GLGGNFAAQYDGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGA 131 Query: 132 ANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAA 191 G A ED G G+ A+G + I + Sbjct: 132 RGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGF------KGIRGHNGL 185 Query: 192 QGISKEDAVQGIANEDAA---QGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGV 248 G+ + G+ E A G + +G+ E G +G V G Sbjct: 186 DGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGP 245 Query: 249 AHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAV 308 A G A G E+ A G A G E G++ G + + Sbjct: 246 AGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGL 305 Query: 309 HGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKE 368 G GVA G A +G+ E G E G Sbjct: 306 TGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKG---- 361 Query: 369 VTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQG 428 G A G E+ G N +A A P G+ + G+ D G Sbjct: 362 --EPGSAGPQGPPGPSGEEGKRG--PNGEAGS--AGPPGPPGLRGSPGSRGLPGADGRAG 415 Query: 429 IANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVA 488 + + G S V+G N DA G E G +G+ G A + Sbjct: 416 VMGPPGSRGASGPAGVRG-PNGDA--GRPGEPGLMG------PRGLPGSPGNIGPAGKEG 466 Query: 489 AHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVAN 548 G+ D P ARG + G D N D H A A G Sbjct: 467 PVGLPGIDGRPGPIGPAGARGEPGNIGFPG-PKGPTGDPGKNGDKGH--AGLAGARGAPG 523 Query: 549 EDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQG 608 D + P G+ QG G+ G + G+ E + G Sbjct: 524 PDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPG 583 Query: 609 VANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPD 668 A G E A G + + G + G E + G V A P Sbjct: 584 PAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGT-------AGPS 636 Query: 669 AAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIA 728 G+ E A GI G E G+ E+ G D +G A G A Sbjct: 637 GPSGLPGERGAAGI------PGGKGEKGEPGLRGEIGNPG---RDGARGAPGAVGAPGPA 687 Query: 729 HEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQ 788 G E G A G E G A + G A G E + Sbjct: 688 ---GATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAK 744 Query: 789 GIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEV 848 G E+ G V A G A + G A G G A G + Sbjct: 745 GPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGIS 804 Query: 849 TAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATED 908 G +G+ G V A+ P A +G + E G Sbjct: 805 GPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFA---GEKGPSGEAGTAGPPGTP 861 Query: 909 VADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVAN 968 G+ A GI ++ E G+A A G + GV Sbjct: 862 GPQGLL--GAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVN- 918 Query: 969 EVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHG 1028 A G A D G G +G G A HG HG Sbjct: 919 --GAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHG 976 Query: 1029 IANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDA 1088 E G A G GI + G G+ + QG+ Sbjct: 977 NRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGL----- 1031 Query: 1089 VQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIAN 1148 GIA G V G G A +D G V G+ QG A Sbjct: 1032 -PGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAG 1090 Query: 1149 EDAAHG 1154 G Sbjct: 1091 PPGPPG 1096 Score = 99.0 bits (245), Expect = 5e-20 Identities = 218/1072 (20%), Positives = 294/1072 (27%), Gaps = 59/1072 (5%) Query: 419 GIANEDAAQ----GIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGI 474 G+ AAQ G+ G+ G A QG G + G Sbjct: 72 GLGGNFAAQYDGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGA 131 Query: 475 ANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAV 534 G A E G + + P ARG G GI + + Sbjct: 132 RGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFK------GIRGHNGL 185 Query: 535 HGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANE 594 G+ + A GV E A +G + +G+ E G A G Sbjct: 186 DGLKGQPGAPGVKGEPGA------PGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGS 239 Query: 595 VAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGV 654 V G A G G E A G A G A +G V L G Sbjct: 240 VGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNA------GPAGPAGPRGEVGLPGLSGP 293 Query: 655 VA--NEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQG---IANEDAAQGIANEVAAHGI 709 V A + A G+ A G+ G A A+G+ E G Sbjct: 294 VGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGS 353 Query: 710 SKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVV 769 E +G QG +G + G A G+ +G+ D Sbjct: 354 KGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGR 413 Query: 770 QGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANE 829 GV +G + V+G + G + G+ G A ++ G+ Sbjct: 414 AGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGI 473 Query: 830 DAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHG 889 D G A+G + G G ++ G+ A+ PD +G Sbjct: 474 DGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAG----ARGAPGPDGNNG 529 Query: 890 IANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVA 949 +G QG E G G+ + + E G A Sbjct: 530 A--QGPPGPQGVQGGKGEQGPPG--PPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPA 585 Query: 950 NEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQ 1009 G E A G + ++G + G E V G G A Sbjct: 586 GPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAV------GTAGPSGPS 639 Query: 1010 GIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANED 1069 G+ E A GI G G D A+G V A G + G E Sbjct: 640 GLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPA---GATGDRGEA 696 Query: 1070 AAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVA 1129 A G A +G E G A + G A G E +G E+ V G Sbjct: 697 GAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPT 756 Query: 1130 NEVEVQGVAHEDAVQGIAN---EDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHED 1186 V G A + G A + G+ A G GI+ G A ++ Sbjct: 757 GPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKE 816 Query: 1187 AVQGIANEDAVHGVAKEVAA---HGVANEDAAHA---IAKPDAARGIANEVAAQGIATED 1240 ++G + G EV A G A E A P G + A GI Sbjct: 817 GLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILG-- 874 Query: 1241 VADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIA 1300 G E GVA V G G A G + G A D G Sbjct: 875 -LPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGND 933 Query: 1301 KEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQ 1360 G +G + G A G HG E G A Sbjct: 934 GPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAV 993 Query: 1361 DIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQG---VANEDAVQGVANEVEVQGVA 1417 QGI + G G+ + +QG +A QG V G Sbjct: 994 GPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPR 1053 Query: 1418 HEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQG 1469 G A +D G V GI QG A G V G Sbjct: 1054 GPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSG 1105 Score = 97.4 bits (241), Expect = 1e-19 Identities = 197/1031 (19%), Positives = 278/1031 (26%), Gaps = 62/1031 (6%) Query: 1208 GVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKED 1267 G A E P ARG A G A ED G GV A G Sbjct: 115 GPAGEPGEPGQTGPAGARGPAGP---PGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTP 171 Query: 1268 AVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVA 1327 + G +GI + + G+ + A G+ E G G + +G+ Sbjct: 172 GLPGF------KGIRGHNGLDGLKGQPGAPGVKGEPGAPGE------NGTPGQTGARGLP 219 Query: 1328 HEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQ 1387 E G A G G A + A G E G A Sbjct: 220 GERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPA 279 Query: 1388 GIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANED 1447 G E + G++ G + G + G+A G G A Sbjct: 280 GPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGAT 339 Query: 1448 AAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIA 1507 A+G+ E G E +G G G + A P G+ Sbjct: 340 GARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLR 399 Query: 1508 NEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAH 1567 ++G+ D G+ + G + +G + G +G+ Sbjct: 400 GSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNI 459 Query: 1568 GVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQ 1627 G A ++ G+ D + A A +P G K+ +G A Sbjct: 460 GPAGKEGPVGLPGIDGRPGPIG---PAGARGEPGNI-GFPGPKGPTGDPGKNGDKGHAGL 515 Query: 1628 DAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1687 A+G +G QG+ QG QG+ G + G+ Sbjct: 516 AGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGL 575 Query: 1688 AKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAA 1747 E G A +G E G + +G + G E G Sbjct: 576 HGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGP 635 Query: 1748 HGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANE 1807 G + +G A +G E + G A P A G E Sbjct: 636 SGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGE 695 Query: 1808 VAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGV 1867 A G A G P E G A G + G E A+G E+ + G Sbjct: 696 AGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGP 755 Query: 1868 ANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAV 1927 V G A + G A G + G+ A GIS Sbjct: 756 TGPVGAAGPAGPNGPPGPA------GSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGP 809 Query: 1928 QGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHE 1987 G A ++ +G + G E A G G + E G QG+ Sbjct: 810 PGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGA 869 Query: 1988 DAVQGIANE------DAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANE 2041 + G+ V G E IA P ARG V + G+ + A G A Sbjct: 870 PGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGV---NGAPGEAGR 926 Query: 2042 DAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQDA 2101 D G N+G D G +G A Sbjct: 927 DGNPG--------------------NDGPPGRDGQPG--HKGERGYPGNIGPVGAAGAPG 964 Query: 2102 AHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVAN 2161 HG G E G A G G+ + G G+ Sbjct: 965 PHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKG 1024 Query: 2162 EDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQG 2221 + +QG + GIA QG G G A +D G V G Sbjct: 1025 HNGLQG------LPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAG 1078 Query: 2222 VANEDAAQGVA 2232 + QG A Sbjct: 1079 IRGPQGHQGPA 1089 Score = 91.3 bits (225), Expect = 1e-17 Identities = 207/1054 (19%), Positives = 274/1054 (25%), Gaps = 65/1054 (6%) Query: 247 GVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 306 G QG A E G T A G A G G E V G Sbjct: 106 GAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGAR 165 Query: 307 AVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVA 366 G G+ + + A G+ E G +G + A G+ Sbjct: 166 GFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPG------ENGTPGQTGARGLP 219 Query: 367 KEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPD--AAHGIANEVAAHGIANED 424 E G G D G V + P A G E+ A G A Sbjct: 220 GE---RGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPA 276 Query: 425 AAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVA 484 G EV G+S G A G+ A+G A V G G+ Sbjct: 277 GPAGPRGEVGLPGLS---GPVGPPGNPGANGLT---GAKGAAGLPGVAGAPGLPGPRGIP 330 Query: 485 KEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAH 544 V A G ARG+ E G E G G Sbjct: 331 GPVGAAGATG------------ARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEE 378 Query: 545 GVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIED 604 G + A P G+ ++G+ D G+ + G + V G + Sbjct: 379 GKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDA 438 Query: 605 AVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAI 664 G G+ G A + G+ D G + G E Sbjct: 439 GRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARG----EPGNIGF 494 Query: 665 AKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAA 724 P G + G A A+G D G G+ QG Sbjct: 495 PGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGF 554 Query: 725 QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHE 784 QG+ G + G+ E G A +G E G + +G Sbjct: 555 QGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRG---- 610 Query: 785 DAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGV 844 G D G V A G A G+ E A G+ G E G+ Sbjct: 611 --PSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIP------GGKGEKGEPGL 662 Query: 845 AKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGI 904 E+ G G V G + A A A + G EV G Sbjct: 663 RGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAG- 721 Query: 905 ATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQ 964 A G E A+ ++ T A G A + G A Sbjct: 722 -PNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDG 780 Query: 965 GVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEV 1024 G G A G + G++ G A K+ ++G + G EV Sbjct: 781 GPPGMTGFPGAAGRTGPPGPS------GISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEV 834 Query: 1025 AAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIA 1084 A G +G + E G G+ + G+ +G+ A G Sbjct: 835 GAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVG-- 892 Query: 1085 HEDAVQGIANEDAVHGVAKEVAAHGV------ANEDPVQGVANEDAVQGVANEVEVQGVA 1138 E GIA G V + GV A D G G +G Sbjct: 893 -EPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYP 951 Query: 1139 HEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVH 1198 G A HG HG E G A G QGI + Sbjct: 952 GNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEP 1011 Query: 1199 GVAKEVAAHGVANEDAAH---AIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVA 1255 G G+ + IA +G V G G A +D G Sbjct: 1012 GEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHP 1071 Query: 1256 NEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQG 1289 V GI QG A G V G Sbjct: 1072 GTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSG 1105 Score = 87.8 bits (216), Expect = 1e-16 Identities = 204/1084 (18%), Positives = 278/1084 (25%), Gaps = 68/1084 (6%) Query: 667 PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG 726 P A + G+ G+ G A G G + G Sbjct: 71 PGLGGNFAAQYDGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAG 130 Query: 727 IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDA 786 G A ED G GV +G + G +GI + Sbjct: 131 ARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGF------KGIRGHNG 184 Query: 787 VQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAK 846 + G+ + A G+ E A G G +G G D + G Sbjct: 185 LDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVG 244 Query: 847 EVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIAT 906 G G + G V N A A P G+ G++ V G Sbjct: 245 PAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGP-AGPRGEVGLP--GLSGPVGPPG--- 298 Query: 907 EDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGV 966 A+G+T + A + GVA G G Sbjct: 299 --------NPGANGLTGAKGAAGLP---------------GVAGAPGLPGPRGIPGPVGA 335 Query: 967 ANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAA 1026 A A+G+ E G E +G QG +G + G A Sbjct: 336 AGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGP 395 Query: 1027 HGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQ----------GIAN 1076 G+ ++G+ D G+ + G S V+G N DA + G+ Sbjct: 396 PGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRG-PNGDAGRPGEPGLMGPRGLPG 454 Query: 1077 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQG 1136 G A ++ G+ D G A G G G + G Sbjct: 455 SPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAG 514 Query: 1137 VAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDA 1196 +A +G D +G G+ QG QG+ G + Sbjct: 515 LA---GARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPG 571 Query: 1197 VHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVAN 1256 G+ E G A A G + ++G + DG E G Sbjct: 572 ERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVG 631 Query: 1257 EVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQG 1316 G S +G A +G E ++G G G G Sbjct: 632 TAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATG 691 Query: 1317 VANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDA 1376 E G A +G E G A + G A E A+G E+ Sbjct: 692 DRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENG 751 Query: 1377 VQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIAN 1436 V G A G A + G A G G A G + G Sbjct: 752 VVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPG 811 Query: 1437 EVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHA 1496 G+ QG G G G A G A Sbjct: 812 PAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPG 871 Query: 1497 IAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDA 1556 I +RG G E GIA A G V + G+ G A D Sbjct: 872 ILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVN---GAPGEAGRDG 928 Query: 1557 VQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIA 1616 G G D G E + AA A HG A Sbjct: 929 NPG------NDGPPGRDGQPGHKGERGYPGNIGPVGAAGA----PGPHGPVGP------A 972 Query: 1617 NKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQ 1676 K +G G A V G S ++G E +G +G + Sbjct: 973 GKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLP 1032 Query: 1677 GIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANED 1736 GIA G V G G A +D G V G+ QG A Sbjct: 1033 GIAGHHGDQGAPGSVGPAGPRGPAGPSGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPP 1092 Query: 1737 AAHG 1740 G Sbjct: 1093 GPPG 1096 Score = 84.7 bits (208), Expect = 1e-15 Identities = 212/1067 (19%), Positives = 289/1067 (27%), Gaps = 84/1067 (7%) Query: 1234 QGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANE 1293 Q + E V G A + G G ED G G G+ Sbjct: 23 QSLQEETVRKGPAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPG------PPGLGGN 76 Query: 1294 DAAQ----GIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDA 1349 AAQ G+ G+ G A QG QG A E G Sbjct: 77 FAAQYDGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGF------QGPAGEPGEPGQTGPAG 130 Query: 1350 AQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVAN 1409 A+G A A ED G +G+ A+G G +G+ Sbjct: 131 ARGPAGPPGK---AGEDGHPGKPGRPGERGVVGPQGARGFP------GTPGLPGFKGIRG 181 Query: 1410 EVEVQGVAHEDAVQGIANEDAA---HGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDA 1466 + G+ + G+ E A +G + A G+ E G A+G Sbjct: 182 HNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVG 241 Query: 1467 VQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIAT------EDV 1520 G A G A G E A A P G EV G++ Sbjct: 242 PVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPG 301 Query: 1521 ADGIANEDAAHGVANEVAAQGIANEVAVHG---VAIEDAVQGVVKEVTAHGVANEDAVQG 1577 A+G+ A G+ A G+ + G A +G+V E G E +G Sbjct: 302 ANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKG 361 Query: 1578 VVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEV 1637 + P+ G A + ++G+ D G+ Sbjct: 362 EPGSAGPQGP-PGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPP 420 Query: 1638 AAHGISKEDAVQGIANEDAAQ----------GIANEDAAQGIAHEDAVQGIANEDAVHGV 1687 + G S V+G N DA + G+ G A ++ G+ D G Sbjct: 421 GSRGASGPAGVRG-PNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGP 479 Query: 1688 AKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAA 1747 A G G G + G+A +G D +G Sbjct: 480 IGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLA---GARGAPGPDGNNGAQGPPGP 536 Query: 1748 HGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANE 1807 G+ QG QG+ + G+ E A P RG E Sbjct: 537 QGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGE 596 Query: 1808 VAAQGIATEDVAD----GIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDP 1863 A G T + G P D G V A G + G+ E A GI Sbjct: 597 SGAAG-PTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGG-- 653 Query: 1864 IQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISK 1923 +G E ++G G A G A G E A A +G Sbjct: 654 -KGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSPG 712 Query: 1924 EDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQG 1983 E G A + G A G E A+G E G A G A + G Sbjct: 713 ERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPG 772 Query: 1984 IAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDA 2043 A G + G+ A P GI+ G A ++ G + Sbjct: 773 PA------GSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGPRGDQG 826 Query: 2044 AHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDA----VQGITNEEAAQAIAKQ 2099 G E A + G A E G A A G A I Sbjct: 827 PVGRTGEVGA-----------VGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGL 875 Query: 2100 DAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGV 2159 + G G E G+A A G V + GV G G Sbjct: 876 PGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGP 935 Query: 2160 ANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAA 2219 D G E +G G A G HG E G A Sbjct: 936 PGRDGQPGHKGE---RGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGA 992 Query: 2220 QGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHG 2266 G QG+ + G + + QG+ HG Sbjct: 993 VGPRGPSGPQGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHG 1039 Score = 84.0 bits (206), Expect = 2e-15 Identities = 173/934 (18%), Positives = 245/934 (26%), Gaps = 36/934 (3%) Query: 1379 GIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEV 1438 G A QG G + G G A ED G G+ Sbjct: 103 GAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQ 162 Query: 1439 AAHGIANEDAA---QGIANEDAAQGIAHEDAVQGIANEDAV---HGVAKEVAAHGVANED 1492 A G +GI + G+ + G+ E +G + A G+ E Sbjct: 163 GARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGER 222 Query: 1493 AAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVA 1552 P ARG V G A + G A G E+ A G A G Sbjct: 223 GRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPR 282 Query: 1553 IEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAA 1612 E + G+ V G + + G L V P G A A Sbjct: 283 GEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPV-GAAGATGA 341 Query: 1613 HSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHE 1672 + + G + +G G +G + G A G+ Sbjct: 342 RGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGS 401 Query: 1673 DAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGI 1732 +G+ D GV + G + V+G + G + +G+ G Sbjct: 402 PGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGP 461 Query: 1733 ANEDAAHGITN------EVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGV 1786 A ++ G+ + G E G G ++ A A G Sbjct: 462 AGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGA 521 Query: 1787 ANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAV 1846 D + P +G+ QG G+P G + G+ E + Sbjct: 522 PGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGL 581 Query: 1847 QGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANE 1906 G A +G E G + +G + G E G G + Sbjct: 582 PGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGL 641 Query: 1907 DAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGI 1966 + A +G E ++G G G A G E A G Sbjct: 642 PGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGP 701 Query: 1967 ANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAA 2026 A +G E G A + G A G E A + G V A Sbjct: 702 AGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGA 761 Query: 2027 QGIATEDVADGIANE------------DAAHGVANEDAAQAIAKPDAAHGIAN-EGIATE 2073 G A + G A A G I+ P G A EG+ Sbjct: 762 AGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGP 821 Query: 2074 DVADG-------IAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANE 2126 G + G E+ A G G + G E Sbjct: 822 RGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGE 881 Query: 2127 DAAHGVANEVAAHG---VANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAI 2183 GVA V G +A A+G V + GV G G +D Sbjct: 882 RGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQ 941 Query: 2184 QGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANE 2243 G E G V A G G A + +G G A V G + Sbjct: 942 PGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGP 1001 Query: 2244 DAARHMAKEDAAQGIANEDAAHGIANEDAVHGIA 2277 R E +G G + GIA Sbjct: 1002 QGIRGDKGEPGEKGPRGLPGLKGHNGLQGLPGIA 1035 Score = 50.4 bits (119), Expect = 2e-05 Identities = 96/518 (18%), Positives = 139/518 (26%), Gaps = 26/518 (5%) Query: 1785 GVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKED 1844 G A E P ARG A G A ED G P GV A G Sbjct: 115 GPAGEPGEPGQTGPAGARGPAGP---PGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTP 171 Query: 1845 AVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIA 1904 + G G+ D ++G V+G G + A G+ E G Sbjct: 172 GLPGFKGIRGHNGL---DGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAP 228 Query: 1905 NEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAH 1964 A+ G + G A G E G A G EV Sbjct: 229 GPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLP 288 Query: 1965 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEV 2024 G++ G + G + G+A + G A ARG+ E Sbjct: 289 GLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEP 348 Query: 2025 AAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANE----GIATEDVADGI- 2079 G E G G + P+ G A G+ + G+ Sbjct: 349 GPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLP 408 Query: 2080 AEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAH 2139 D G+ ++ + G + G + +G+ G A + Sbjct: 409 GADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPV 468 Query: 2140 GVANEDAAQGVANEVAAQGVAN---------------EDAVQGVANEVEVQGIAHKDAIQ 2184 G+ D G A+G ++ +G A +G D Sbjct: 469 GLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNN 528 Query: 2185 GIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANED 2244 G QGV G QG+ G + +G+ E + G A Sbjct: 529 GAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPR 588 Query: 2245 AARHMAKEDAAQGIANEDAAHGIANEDAVHGIANEDAV 2282 R E A G + G + G E V Sbjct: 589 GERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGV 626 Score = 45.1 bits (105), Expect = 8e-04 Identities = 69/356 (19%), Positives = 96/356 (26%), Gaps = 6/356 (1%) Query: 1931 ANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAV 1990 A Q +G+ G+ G A G G + G Sbjct: 78 AAQYDGKGVGLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGP 137 Query: 1991 QGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAA---QGIATEDVADGIANEDAAHGV 2047 G A ED G + P ARG +GI + DG+ + A GV Sbjct: 138 PGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGV 197 Query: 2048 ANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDA-VQGITNEEAAQAIAKQDAAHGIT 2106 E A G G+ E G A +G A + G Sbjct: 198 KGEPGAPGENGTPGQTGA--RGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPP 255 Query: 2107 KEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQ 2166 A G E+ A G A G EV G++ G G + Sbjct: 256 GFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLP 315 Query: 2167 GVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANED 2226 GVA + G G A A+G+ E G E +G QG Sbjct: 316 GVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPS 375 Query: 2227 AAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVHGIANEDAV 2282 +G G A + ++G+ D G+ G + V Sbjct: 376 GEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGV 431 >gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo sapiens] Length = 1650 Score = 100 bits (248), Expect = 2e-20 Identities = 202/1083 (18%), Positives = 298/1083 (27%), Gaps = 68/1083 (6%) Query: 959 NEDAAQGVANEVAAQGVAN--EDAVHGVANEDAVQGVANEVE----VQGIAHKDAIQGIA 1012 ++D G E+ + E+A HG +G +E V+G + G+ Sbjct: 265 SQDPTPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLI 324 Query: 1013 NEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQ-GIANEDAA 1071 G V G G+ D A G G S + G D Sbjct: 325 GPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPG------PPGTSLMLPFRFGSGGGDKG 378 Query: 1072 QGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANE 1131 +A ++A + A + G G ++G + + QG Sbjct: 379 PVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGP 438 Query: 1132 VEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGI 1191 + G + +G A D A G+ + G D G+ E +G + G Sbjct: 439 QGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGP 498 Query: 1192 ANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAA 1251 ED G E+ G+ E + P GI +G+ G Sbjct: 499 PGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGE 558 Query: 1252 HGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQG-IAKEDPVQGVAN 1310 G + G QG +G + + G+ D G KE P N Sbjct: 559 PGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGN 618 Query: 1311 EDPI--QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAA 1368 + P QG +GV D ++G+ +G ED + Sbjct: 619 QGPSGPQGPLGYPGPRGVKGVDGIRGLKGH------------KGEKGEDGFPGFKGDIGV 666 Query: 1369 QGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANE 1428 +G E V G ED +G G + G ++ V G + G Sbjct: 667 KGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPG------LPGYPGR 720 Query: 1429 DAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGV 1488 G G + E A+G++ + +G E G + G + A G Sbjct: 721 QGPKGSLGFPGFPGASGEKGARGLSGKSGPRG---ERGPTGPRGQRGPRGATGKSGAKGT 777 Query: 1489 ANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAV 1548 + D H P RG+ G G +D G + G + Sbjct: 778 SGGDGPHG---PPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGP 834 Query: 1549 HGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIAN 1608 G QG E G G E L A ++ + P A G Sbjct: 835 PGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPG-TAGKEGTKGDPGPPGAPG--- 890 Query: 1609 EVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQ---GIANEDAAQGIANEDA 1665 KD G+ +G+ G+ + G A +G A Sbjct: 891 ---------KDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGG 941 Query: 1666 AQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAH 1725 G QG GV E G D VQG G+ GVA Sbjct: 942 PIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPV------GLPGPAGPPGVAG 995 Query: 1726 EDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHG 1785 ED +G + G HG G + G E A G Sbjct: 996 EDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKG 1055 Query: 1786 VANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDA 1845 + P +G+ +G + G P G A A G Sbjct: 1056 DEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPG 1115 Query: 1846 VQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIAN 1905 G +G E G+ E V+G E +G E G +G Sbjct: 1116 GVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGE---RGEKGESGQPGEPGPPGPKGPTG 1172 Query: 1906 EDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHG 1965 +D + G G QD A+G ED G + + G E G Sbjct: 1173 DDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG---QPGSPGPTGENGPPG 1229 Query: 1966 IANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVA 2025 + G + QG G G PD RG+ V Sbjct: 1230 PLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVG 1289 Query: 2026 AQG 2028 QG Sbjct: 1290 QQG 1292 Score = 94.7 bits (234), Expect = 9e-19 Identities = 191/1067 (17%), Positives = 289/1067 (27%), Gaps = 62/1067 (5%) Query: 923 KEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVH 982 +E AQAI +Q A ++ G G +G + ++ QG + Sbjct: 384 QEAQAQAILQQ-ARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLT 442 Query: 983 GVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANED 1042 G + +G A +G+ ++G D G+ E G G ED Sbjct: 443 GPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED 502 Query: 1043 AAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVA 1102 +G E+ G+ E +G+ GI +G+ +G G Sbjct: 503 GERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPP 562 Query: 1103 KEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAA- 1161 + G QG +G + + G+ D G ++ G Sbjct: 563 GQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPS 622 Query: 1162 -----------HGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVA 1210 G+ D +G+ +G ED G + V G EV G Sbjct: 623 GPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG---EDGFPGFKGDIGVKGDRGEVGVPGSR 679 Query: 1211 NEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQ 1270 ED P+ +G G G+ E GV + Sbjct: 680 GEDG------PEGPKGRTGPTGDPG------PPGLMGEKGKLGV------------PGLP 715 Query: 1271 GIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHED 1330 G +G G + E A+G++ + G E G + +G + Sbjct: 716 GYPGRQGPKGSLGFPGFPGASGEKGARGLSGK---SGPRGERGPTGPRGQRGPRGATGKS 772 Query: 1331 AVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIA 1390 +G + D HG E +G+ G +D + G + G Sbjct: 773 GAKGTSGGDGPHGPPGE---RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQ 829 Query: 1391 KEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQ 1450 + G QG A E G G E G A + G A Sbjct: 830 GKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAP 889 Query: 1451 GIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEV 1510 G +G E + G A + G G A A G Sbjct: 890 GKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP 949 Query: 1511 ATQGIATEDVADGIANEDAAHGVANEVAAQ---GIANEVAVHGVAIEDAVQGVVKEVTAH 1567 QG G+ E G Q G+ GVA ED +G V + Sbjct: 950 GPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQK 1009 Query: 1568 GVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQ 1627 G G V AA A +P A G A G Sbjct: 1010 GTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEP-GARGPQGHFGAKGDEGTRGFNGPPGP 1068 Query: 1628 DAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1687 QG+ G + + G +G A + A G G G Sbjct: 1069 IGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1128 Query: 1688 AKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAA 1747 E + G+ E V+G E +G + + G +G +D G V Sbjct: 1129 PGESGSPGIQGEPGVKGPRGERGEKGESGQ---PGEPGPPGPKGPTGDDGPKGNPGPVGF 1185 Query: 1748 HGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANE 1807 G G +D +G ED E G + P RG A Sbjct: 1186 PGDPGPPGEGGPRGQDGAKGDRGEDG------EPGQPGSPGPTGENGPPGPLGKRGPAGS 1239 Query: 1808 VAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGV 1867 ++G A G P A G V G + + G+ + G + G Sbjct: 1240 PGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVG---QQGRPGA 1296 Query: 1868 ANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAV 1927 + G + G+ + A G G+ Q + G Sbjct: 1297 TGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQ 1356 Query: 1928 QGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQG 1974 +G A G G+ +G G E QG Sbjct: 1357 KGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQG 1403 Score = 94.7 bits (234), Expect = 9e-19 Identities = 173/939 (18%), Positives = 255/939 (27%), Gaps = 28/939 (2%) Query: 62 ADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQG 121 AD A G+ + V+G G+ E G G ED +G E+ +G Sbjct: 456 ADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRG 515 Query: 122 VANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDA 181 + E +G+ G+ V+G+ G G + Sbjct: 516 LPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPG 575 Query: 182 AQDIANEDAAQGISKEDAVQGIANEDAAQG-IAKEDPVQGVANEDP--VQGVANEDAVQG 238 Q +G + + G+ D G KE P N+ P QG +G Sbjct: 576 PQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRG 635 Query: 239 VANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDA 298 V V G+ +G ED G ++ G E G ED +G Sbjct: 636 VKG---VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTG 692 Query: 299 VQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIAN 358 G + G ++ G+ G +G G Sbjct: 693 PTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG 752 Query: 359 EDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAH 418 E G + G + +G D HG + + P +G Sbjct: 753 ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHG----PPGERGLPGPQGPNGFPGPKGPP 808 Query: 419 GIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANED 478 G +D G + G + G QG A E G G E Sbjct: 809 GPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQ 868 Query: 479 AVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVA 538 + G A + G A P RG E G A G G A Sbjct: 869 GLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPA 928 Query: 539 NEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVH 598 G A G +G+ E G D GV V + Sbjct: 929 GSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRD---GVQGPVGLP 985 Query: 599 GVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANE 658 G A GVA ED G + +G HG G V + G E Sbjct: 986 GPA---GPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAG-ADGE 1041 Query: 659 DAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGI 718 A+ A G +G QG+ +G +V G +G Sbjct: 1042 PGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGP 1101 Query: 719 ANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEV 778 A + A G G G E + G+ E V+G E +G E Sbjct: 1102 AGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGE---RGEKGESGQ 1158 Query: 779 QGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANE 838 G +G +D G V G G +D A+G ED G + Sbjct: 1159 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGED---GEPGQ 1215 Query: 839 DAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANE 898 + G E G + G E G + AI P + G A + Sbjct: 1216 PGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1275 Query: 899 VAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVA 958 G+ + + + G T + + + A+G G+ Sbjct: 1276 PGPDGL--RGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLI 1333 Query: 959 NEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEV 997 QG E +G+ G E + G + + Sbjct: 1334 GPPGEQG---EKGDRGLPGPQGSPGQKGEMGIPGASGPI 1369 Score = 90.9 bits (224), Expect = 1e-17 Identities = 195/1042 (18%), Positives = 294/1042 (28%), Gaps = 72/1042 (6%) Query: 392 VVANEDAAQAIAK--------PDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDA 443 V A E AQAI + P G G +G + ++ G Sbjct: 381 VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQG 440 Query: 444 VQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAK 503 + G + +G A D A+G+ + V+G D + G+ E G Sbjct: 441 LTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 500 Query: 504 PDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHG 563 D RG E+ +G+ E G+ G+ G+ P G Sbjct: 501 EDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPG 560 Query: 564 IANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANE-- 621 + T G G G + + G+ D G ++ G Sbjct: 561 PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQG 620 Query: 622 -DAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAH 680 QG GV D ++G+ G ED G EV Sbjct: 621 PSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG----EDGFPGFKGDIGVKGDRGEVGVP 676 Query: 681 GIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANED 740 G ED +G G G + V G+ QG +G Sbjct: 677 GSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQG------PKGSLGFP 730 Query: 741 AVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIA 800 G + E A G++ + G E G + +G + +G + D HG Sbjct: 731 GFPGASGEKGARGLSGK---SGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPP 787 Query: 801 NEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQ 860 E G+ G G +D + G G EV G T Sbjct: 788 GE---RGLPGPQGPNGFPGPKGPPGPPGKDGLPG------HPGQRGEVGFQGKTGPPGPP 838 Query: 861 GVVNEEALHGVVA--NEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAA 918 GVV + G E P G+ G A + +G A G KD Sbjct: 839 GVVGPQGAAGETGPMGERGHPGPPGPPGEQGL--PGTAGKEGTKGDPGPPGAPG--KDGP 894 Query: 919 HGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANE 978 G+ + + + + G + G E A G + G Sbjct: 895 AGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPG---ERGAAGSGGPIGPPGRPGP 951 Query: 979 DAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGI 1038 G A E V G + G +D +QG G+ G+A ED +G Sbjct: 952 QGPPGAAGEKGVPGEKGPI---GPTGRDGVQGPV------GLPGPAGPPGVAGEDGDKGE 1002 Query: 1039 ANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAV 1098 + +G HG G + A G E A+G +G ++ Sbjct: 1003 VGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKG---DEGT 1059 Query: 1099 HGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANE 1158 G +G +QG+ +G +V G +G A + A G Sbjct: 1060 RGF------NGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGP 1113 Query: 1159 VAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAI 1218 G +G E + GI E V+G E G E G Sbjct: 1114 PGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGE---RGEKGESGQPGEPGPPGPKGP 1170 Query: 1219 AKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAA 1278 D +G V G G +D A G E G + G E+ Sbjct: 1171 TGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG---QPGSPGPTGENGP 1227 Query: 1279 QGIAKEDAVQGIANEDAAQG--IAKEDP-VQGVANEDPIQGVANEVEVQGVAHEDAVQGI 1335 G + G + QG AK DP G + G A G + G Sbjct: 1228 PGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGS 1287 Query: 1336 ANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPV 1395 + G + G + + A+G + G+ QG E Sbjct: 1288 VGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQG---EKGD 1344 Query: 1396 QGVANEDAVQGVANEVEVQGVA 1417 +G+ G E+ + G + Sbjct: 1345 RGLPGPQGSPGQKGEMGIPGAS 1366 Score = 90.5 bits (223), Expect = 2e-17 Identities = 190/1017 (18%), Positives = 273/1017 (26%), Gaps = 73/1017 (7%) Query: 916 DAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGV 975 D A G+ + + D + E +G G ED +G E+ +G+ Sbjct: 457 DGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGL 516 Query: 976 ANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAA 1035 E G+ G+ V+G+ +G G + G Sbjct: 517 PGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGP 576 Query: 1036 QGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANE 1095 QG +G + G+ D G ++ G G G Sbjct: 577 QGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGV 636 Query: 1096 DAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGI 1155 V G+ G ED G + V+G EV V G ED +G G Sbjct: 637 KGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEG---PKGRTGP 693 Query: 1156 ANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAA 1215 + G+ E G+ G +G G + E A G++ + Sbjct: 694 TGDPGPPGLMGEKGKLGV---PGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGP 750 Query: 1216 HAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANE 1275 P RG + +G + A G + D HG E G+ G Sbjct: 751 RGERGPTGPRG---QRGPRGATGKSGAKGTSGGDGPHGPPGE---RGLPGPQGPNGFPGP 804 Query: 1276 DAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGI 1335 G +D + G + G + G QG A E G G Sbjct: 805 KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGP 864 Query: 1336 ANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPV 1395 E G A ++ +G A +G E + G A +G Sbjct: 865 PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP 924 Query: 1396 QGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANE 1455 G A +G A G QG G+ E G D QG Sbjct: 925 PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQG---- 980 Query: 1456 DAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGI 1515 G+ G+A ED G + G H P G + G Sbjct: 981 --PVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAG- 1037 Query: 1516 ATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAV 1575 ADG E A G A+G +G +QG+ G + E Sbjct: 1038 -----ADG---EPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGL------PGPSGEKGE 1083 Query: 1576 QGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIAN 1635 G V P G A A G +G Sbjct: 1084 TGDV-------------GPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG 1130 Query: 1636 EVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHG 1695 E + GI E V+G E +G E G +G +D G V G Sbjct: 1131 ESGSPGIQGEPGVKGPRGERGEKG---ESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPG 1187 Query: 1696 VANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDA 1755 G +D +G +G E G +G + G A Sbjct: 1188 DPGPPGEGGPRGQDGAKG------DRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPG 1241 Query: 1756 AQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIAT 1815 ++G +G V G A + PD RG+ V QG Sbjct: 1242 SEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPG------PDGLRGLPGSVGQQGRPG 1295 Query: 1816 EDVADGIP---NEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVE 1872 G P G+ + A G + G+ QG + + G Sbjct: 1296 ATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPG------ 1349 Query: 1873 VQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQG 1929 QG + GI G G A A+ +G E VQG Sbjct: 1350 PQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKG---EKGVQG 1403 Score = 88.6 bits (218), Expect = 7e-17 Identities = 172/896 (19%), Positives = 247/896 (27%), Gaps = 79/896 (8%) Query: 654 VVANEDAAQAIAK--------PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVA 705 V A E AQAI + P G G +G + + QG Sbjct: 381 VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQG 440 Query: 706 AHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVAN 765 G + +G A D A+G+ + V+G D + G+ E G + G Sbjct: 441 LTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 500 Query: 766 EDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQG 825 ED +G E+ +G+ E +G+ GI GV D QG QG Sbjct: 501 EDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIP---GPPGVRGMDGPQGPKGSLGPQG 557 Query: 826 VANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPD 885 G G + HG E QG + L G+ ++ K Sbjct: 558 EPGPPGQQGTPGTQGLPGPQGAIGPHG---EKGPQG---KPGLPGMPGSDGPPGHPGKEG 611 Query: 886 AAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAA 945 N+G + G G+ Sbjct: 612 PPGTKGNQGPSGPQGPLGYPGPRGVKGV-------------------------------- 639 Query: 946 QGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHK 1005 G+ G ED G ++ +G E V G ED +G G Sbjct: 640 DGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGP 699 Query: 1006 DAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGI 1065 + G + G+ G +G G + E A G+S + +G Sbjct: 700 PGLMGEKGKLGVPGLP------GYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG- 752 Query: 1066 ANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAV 1125 E G + +G + +G + D HG E +G+ Sbjct: 753 --ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGE------------RGLPGPQGP 798 Query: 1126 QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHE 1185 G G +D + G + G + G QG A E G Sbjct: 799 NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 858 Query: 1186 DAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGI 1245 G E + G A + G A P RG E G A G Sbjct: 859 PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 918 Query: 1246 ANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPV 1305 G A G + G QG +G+ E G D V Sbjct: 919 EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGV 978 Query: 1306 QG-VANEDPI--QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDI 1362 QG V P GVA E +G + +G HG G + A Sbjct: 979 QGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGA 1038 Query: 1363 ANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAV 1422 E A+G +G G +QG+ +G +V G Sbjct: 1039 DGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGP 1098 Query: 1423 QGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE 1482 +G A + A G G +G E + GI E V+G E G + + Sbjct: 1099 RGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQ 1158 Query: 1483 ------VAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHG 1532 G +D P G G +D A G ED G Sbjct: 1159 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG 1214 Score = 87.4 bits (215), Expect = 1e-16 Identities = 177/965 (18%), Positives = 263/965 (27%), Gaps = 65/965 (6%) Query: 1306 QGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANE 1365 +G A D +G+ + V+G D + G+ E G G ED + E Sbjct: 451 RGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGE 510 Query: 1366 DAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGI 1425 +G+ E +G+ GI V+G+ D QG + QG QG Sbjct: 511 IGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGM---DGPQGPKGSLGPQGEPGPPGQQGT 567 Query: 1426 ANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAA 1485 G + HG G+ + G +G G + Sbjct: 568 PGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPS---GP 624 Query: 1486 HGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANE 1545 G + D RG+ +G ED G ++ +G E Sbjct: 625 QGPLGYPGPRGVKGVDGIRGLKGHKGEKG------------EDGFPGFKGDIGVKGDRGE 672 Query: 1546 VAVHGVAIEDAVQGVVKEVTAHGVANEDAV---QGVVNEDALHSVVANEDAAQAIAKPDA 1602 V V G ED +G G + +G + L + ++ P Sbjct: 673 VGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGF 732 Query: 1603 AHGIANEVAAHSIANKDAAQGIAN------QDAAQGIANEVAAHGISKEDAVQGIANEDA 1656 G + E A ++ K +G Q +G + A G S D G E Sbjct: 733 P-GASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGE-- 789 Query: 1657 AQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVAN 1716 +G+ G G +D + G G E QG GV Sbjct: 790 -RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHP------GQRGEVGFQGKTGPPGPPGV-- 840 Query: 1717 EVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHS 1776 V QG A E G G E G A ++ +G G + Sbjct: 841 -VGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRG 899 Query: 1777 VAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVA 1836 E G A P G A +G A G P G Sbjct: 900 FPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAG 959 Query: 1837 AHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIAN 1896 G+ E G D QG P+ G+ GVA ED +G + G Sbjct: 960 EKGVPGEKGPIGPTGRDGVQG-----PV-GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKG 1013 Query: 1897 EDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQG 1956 G + A G E +G A+G ++ +G G Sbjct: 1014 NKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKG---DEGTRGF------NG 1064 Query: 1957 IANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDA 2016 + G+ +G + G +G A + G P Sbjct: 1065 PPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPG 1124 Query: 2017 ARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVA 2076 +G E + GI E G E G + + P G ++G Sbjct: 1125 EKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTG--DDGPKGNPGP 1182 Query: 2077 DGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEV 2136 G D G E + QD A G ED G G G Sbjct: 1183 VGFPGDP--GPPGEGGPRG---QDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPA 1237 Query: 2137 AAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVA 2196 + G +G + A G + G A G + G + G Sbjct: 1238 GSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGAT 1297 Query: 2197 NEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQ 2256 + G G+ + A+G E G+ + G E R + + Sbjct: 1298 GQAGPPGPVGPPGLPGLRGDAGAKG---EKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSP 1354 Query: 2257 GIANE 2261 G E Sbjct: 1355 GQKGE 1359 Score = 86.3 bits (212), Expect = 3e-16 Identities = 217/1217 (17%), Positives = 330/1217 (27%), Gaps = 87/1217 (7%) Query: 16 SSEESLVHKDRGDGERPVNVRVVQVAPLRHESTPYEDT--VHDIANEDADAAHGITNEDA 73 S E+ + + G ERP N + P R + +P + +H N++ + +D Sbjct: 220 SCEQKELECEGGQRERPQNQQ-----PHRAQRSPQQQPSRLHRPQNQEPQS------QDP 268 Query: 74 VQGVANEVAAQGVAN--EDAAHGVANEVAAHG----------VANEDAAQGVANEVAAQG 121 G E+ + E+AAHG G V +G A + G Sbjct: 269 TPGEEEEILESSLLPPLEEAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPG 328 Query: 122 VANEDAVQGVANEDAVQGVANEDAVQGIANEDAAH-------GIANEDAAQGIANEDAAQ 174 + G E G A G G D +A ++A Sbjct: 329 IQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQA 388 Query: 175 DIAKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANED 234 + A + G + G +G + + QG + G + Sbjct: 389 QAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKA 448 Query: 235 AVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIA 294 +G A +G+ + V+G D G+ E G G ED +G Sbjct: 449 GRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDD 508 Query: 295 HEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVAD 354 E +G+ E G+ G+ + D G + QG Sbjct: 509 GEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGM---DGPQGPKGSLGPQGEPGPPGQQ 565 Query: 355 GIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANE 414 G G + HG E QG + L G+ ++ P G Sbjct: 566 GTPGTQGLPGPQGAIGPHG---EKGPQG---KPGLPGMPGSDG-------PPGHPGKEGP 612 Query: 415 VAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGI 474 G QG G+ D ++G+ +G ED G + V+G Sbjct: 613 PGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG---EDGFPGFKGDIGVKGD 669 Query: 475 ANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGI---ATEDVADGIANE 531 E V G E G + P G ++ G+ G Sbjct: 670 RGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGF 729 Query: 532 DAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGV 591 G + E A G++ + P G + +G + A G + D HG Sbjct: 730 PGFPGASGEKGARGLSGKSGPRGERGPTGPRG---QRGPRGATGKSGAKGTSGGDGPHGP 786 Query: 592 ANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDAL 651 E + G + G G G EV G GVV Sbjct: 787 PGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQG- 845 Query: 652 HGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISK 711 A E G E G A ++ +G A G G Sbjct: 846 ---AAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPG 902 Query: 712 EDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQG 771 E + G A +G G A G A G QG +G Sbjct: 903 ERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKG 962 Query: 772 VANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDA 831 V E G D VQG G+ GVA ED +G + +G Sbjct: 963 VPGEKGPIGPTGRDGVQGPV------GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKG 1016 Query: 832 VHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIA 891 HG G + A G E +G H ++ + P G+ Sbjct: 1017 EHGPPGPPGPIGPVGQPGAAGADGEPGARGPQG----HFGAKGDEGTRGFNGPPGPIGL- 1071 Query: 892 NEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANE 951 +G+ +G T DV G + A + A G Sbjct: 1072 -QGLPGPSGEKG-ETGDV-------GPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGP 1122 Query: 952 DAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGI 1011 G E + G+ E +G E G E G +G D +G Sbjct: 1123 PGEKGEPGESGSPGIQGEPGVKGPRGE---RGEKGESGQPGEPGPPGPKGPTGDDGPKGN 1179 Query: 1012 ANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAA 1071 G G +D A+G ED G G + G + Sbjct: 1180 PGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGS 1239 Query: 1072 QGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANE 1131 G +G + G + G A G + G + G + Sbjct: 1240 PGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQ 1299 Query: 1132 VEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGI 1191 G + G+ + A G G+ QG E +G+ G Sbjct: 1300 AGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQG---EKGDRGLPGPQGSPGQ 1356 Query: 1192 ANEDAVHGVAKEVAAHG 1208 E + G + + G Sbjct: 1357 KGEMGIPGASGPIGPGG 1373 Score = 85.5 bits (210), Expect = 6e-16 Identities = 192/1049 (18%), Positives = 293/1049 (27%), Gaps = 76/1049 (7%) Query: 67 GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126 G T G +G + + G G + +G A A+G+ + Sbjct: 407 GYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDP 466 Query: 127 AVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIA 186 V+G D + G+ E +G G ED +G E + + E + + Sbjct: 467 GVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLL 526 Query: 187 NEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQ 246 GI V+G+ +G G + G QG + Sbjct: 527 GPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEK 586 Query: 247 GVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 306 G + + G+ D G + G G QG +G+ D Sbjct: 587 GPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSG------PQGPLGYPGPRGVKGVD 640 Query: 307 AVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVA 366 + G+ G ED G EV G ED +G G Sbjct: 641 GIRGLK---GHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTG-- 695 Query: 367 KEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAA 426 + G+ E GV L G + ++ P G + E A G++ + Sbjct: 696 -DPGPPGLMGEKGKLGV---PGLPGYPGRQGPKGSLGFP-GFPGASGEKGARGLSGKSGP 750 Query: 427 QGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKE 486 +G G + +G + A+G + D G E +G+ +G Sbjct: 751 RGERGPTGPRG---QRGPRGATGKSGAKGTSGGDGPHGPPGE---RGLPGPQGPNGFPGP 804 Query: 487 VAAHGVANKDA--AHAIAKPDAA-------RGIANEVAAQGIATEDVADGIANEDAVHGV 537 G KD H + + G V QG A E G G Sbjct: 805 KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGP 864 Query: 538 ANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAV 597 E G A ++ P A G +G E G A G Sbjct: 865 PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP 924 Query: 598 HGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVAN 657 G A +G A G QG GV E G D + G V Sbjct: 925 PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPV-- 982 Query: 658 EDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQG 717 G+ G+A ED +G + +G HG G Sbjct: 983 --------------GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIG 1028 Query: 718 IANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVE 777 + A G E +G G +G +QG+ +G +V Sbjct: 1029 PVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVG 1088 Query: 778 VQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVAN 837 G +G A + A G G +G E + G+ E V G Sbjct: 1089 PMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRG 1148 Query: 838 EDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVAN 897 E +G + G E G G N + P G Sbjct: 1149 ERGEKGES------GQPGEPGPPGPKGPTGDDGPKGNPG---PVGFPGDPGPPGEGGPRG 1199 Query: 898 EVAAQGIATEDVADGIAKDAAHGITKEEAAQA-IAKQDAAHSITNE--DAAQGVANEDAA 954 + A+G ED G + + G T E + K+ A S +E +G + A Sbjct: 1200 QDGAKGDRGEDGEPG--QPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGA 1257 Query: 955 HGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANE 1014 G + G A G + G + G + G + G+ + Sbjct: 1258 IGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGD 1317 Query: 1015 DAAH------GIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGIS------KEDAV 1062 A G+ + G E +G+ + G E+ G S + Sbjct: 1318 AGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGL 1377 Query: 1063 QGIANEDAAQGIANEDAAQGIAHEDAVQG 1091 G A A+G +G E VQG Sbjct: 1378 PGPAGPKGAKGATGPGGPKG---EKGVQG 1403 Score = 75.5 bits (184), Expect = 6e-13 Identities = 153/878 (17%), Positives = 231/878 (26%), Gaps = 40/878 (4%) Query: 1413 VQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQ---- 1468 V+G + G+ G V G G+ D A G + Sbjct: 311 VEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRF 370 Query: 1469 GIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANED 1528 G D VA + A + A A+ P G G G + + Sbjct: 371 GSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDL 430 Query: 1529 AAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVV 1588 G G + G A D +G+ + G D + G+ E Sbjct: 431 GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRG-- 488 Query: 1589 ANEDAAQAIAKP---DAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKE 1645 + AQ + P D G E+ + + +G+ GI G+ Sbjct: 489 --DTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGP 546 Query: 1646 DAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGV 1705 +G G + G QG G + G+ D G Sbjct: 547 QGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH 606 Query: 1706 ANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAV 1765 ++ G G G GI G ED G + V Sbjct: 607 PGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGV 666 Query: 1766 QGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNE 1825 +G E V E G P G ++ G+ G P Sbjct: 667 KGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLP------GYPGR 720 Query: 1826 DAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGI 1885 G G S E +G++ + +G E G + +G + +G Sbjct: 721 QGPKGSLGFPGFPGASGEKGARGLSGKSGPRG---ERGPTGPRGQRGPRGATGKSGAKGT 777 Query: 1886 ANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAV 1945 + D HG E +G+ G +D + G Q G + Sbjct: 778 SGGDGPHGPPGE---RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGP 834 Query: 1946 QGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANE 2005 G QG A E G G E G A ++ +G + G + Sbjct: 835 PGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKG---DPGPPGAPGK 891 Query: 2006 DAAHAIAKPDAARGIANEVAAQGIATEDVADG------IANEDAAHGVANEDAAQAIAKP 2059 D + RG+ G+ + G E A G P Sbjct: 892 DGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGP 951 Query: 2060 DAAHGIANE-GIATEDVADG-IAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNE 2117 G A E G+ E G D VQG + G+ ED +G + Sbjct: 952 QGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVG------LPGPAGPPGVAGEDGDKGEVGD 1005 Query: 2118 VAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGI 2177 +G HG G + A G E A+G +G G Sbjct: 1006 PGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGP 1065 Query: 2178 AHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAV 2237 +QG+ +G +V G +G A A G G Sbjct: 1066 PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGE 1125 Query: 2238 HGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVHG 2275 G E + + E +G E G + + G Sbjct: 1126 KGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPG 1163 Score = 56.6 bits (135), Expect = 3e-07 Identities = 85/483 (17%), Positives = 132/483 (27%), Gaps = 13/483 (2%) Query: 1798 PDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQG 1857 P G + +G A D A G+P + G G+ E +G G Sbjct: 438 PQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPG 497 Query: 1858 IAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAN--- 1914 ED +G E+ +G+ E +G+ GI +G+ + Sbjct: 498 PPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQG 557 Query: 1915 EDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQG 1974 E G QG+ A G E QG G G +G Sbjct: 558 EPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKG 617 Query: 1975 IANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDV 2034 QG +G+ D + G+ D G ++ +G E Sbjct: 618 NQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG---EDGFPGFKGDIGVKGDRGEVG 674 Query: 2035 ADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQ 2094 G ED G P G + + + +G Sbjct: 675 VPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK-LGVPGLPGYPGRQGPKGSLGFPGFP 733 Query: 2095 AIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEV 2154 + + A G++ + +G E G + G + A G + D G E Sbjct: 734 GASGEKGARGLSGKSGPRG---ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGE- 789 Query: 2155 AAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVA 2214 +G+ G G KD + G + G + G QG A Sbjct: 790 --RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAA 847 Query: 2215 NEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVH 2274 E G G E + G A ++ + A G G E + Sbjct: 848 GETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLP 907 Query: 2275 GIA 2277 G A Sbjct: 908 GTA 910 Score = 37.7 bits (86), Expect = 0.14 Identities = 73/380 (19%), Positives = 103/380 (27%), Gaps = 34/380 (8%) Query: 1927 VQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQ---- 1982 V+G + G+ +QG G G+ D A G Sbjct: 311 VEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRF 370 Query: 1983 GIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANED 2042 G D +A ++A + A A+ P G G + + G+ E Sbjct: 371 GSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLG---QPGSPGLKGES 427 Query: 2043 AAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAED----------AVQGITNEEA 2092 G Q + P G G A D A G+ D + G+ E+ Sbjct: 428 GDLGPQGPRGPQGLTGPPGKAG--RRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKG 485 Query: 2093 AQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANE------DA 2146 + G ED +G E+ +G+ E G+ G+ D Sbjct: 486 HRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDG 545 Query: 2147 AQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVAN 2206 QG + QG QG QG+ G E QG G Sbjct: 546 PQGPKGSLGPQGEPGPPGQQGTPG---TQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG 602 Query: 2207 EDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAK------EDAAQGIAN 2260 G +G QG GV D R + ED G Sbjct: 603 PPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKG 662 Query: 2261 EDAAHGIANEDAVHGIANED 2280 + G E V G ED Sbjct: 663 DIGVKGDRGEVGVPGSRGED 682 >gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo sapiens] Length = 1818 Score = 99.8 bits (247), Expect = 3e-20 Identities = 204/1077 (18%), Positives = 301/1077 (27%), Gaps = 68/1077 (6%) Query: 923 KEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVH 982 +E AQAI +Q A ++ G+ G A+G + + QG Sbjct: 524 QEAQAQAILQQ-ARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPP 582 Query: 983 GVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANED 1042 G + +G +G+ + +G D G+ + G G +D Sbjct: 583 GPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDD 642 Query: 1043 AAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVA 1102 +G E+ G+ E +G+ G + G+A D G Sbjct: 643 GMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQ------------PGMAGVDGPPGPK 690 Query: 1103 KEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAH 1162 + G QG + G + G G+A A G Sbjct: 691 GNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKE 750 Query: 1163 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPD 1222 G + E A G QG +G+ D V G+ + G ED Sbjct: 751 GQSGEKGALG---PPGPQGPIGYPGPRGVKGADGVRGLK---GSKGEKGEDGFPGFKGDM 804 Query: 1223 AARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIA 1282 +G EV G ED +G G G + V G+ QG Sbjct: 805 GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 864 Query: 1283 KEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAH 1342 G + +G +GVA + +G +G +G + Sbjct: 865 GSTGFPGFPGANGEKG------ARGVAGKPGPRGQRGPTGPRG---SRGARGPTGKPGPK 915 Query: 1343 GIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANED 1402 G + D G E Q G G +D G + G + Sbjct: 916 GTSGGDGPPGPPGERGPQ---GPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKT 972 Query: 1403 AVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIA 1462 G V QG E G G E G A ++ A+G + QGI+ Sbjct: 973 GPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKG---DPGPQGIS 1029 Query: 1463 HEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVAD 1522 +D G+ G+ A G+ + P + G T G Sbjct: 1030 GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAG------PI 1083 Query: 1523 GIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVA---NEDAVQGVV 1579 G+ G +G E G A D VQG V G A ED +G + Sbjct: 1084 GLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEI 1143 Query: 1580 NEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAA 1639 E ++ P G+ V A IA D G Q G + A Sbjct: 1144 GEPGQKGSKGDKGE----NGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGA 1199 Query: 1640 HGISKEDAVQGIANEDAAQGIANED---------------AAQGIAHEDAVQG-IANEDA 1683 G G+ G E+ QG D QG + + Sbjct: 1200 RGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGS 1259 Query: 1684 VHGVAKEVAAHGVANEDP--VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGI 1741 V GV ++ N P GV +G E G A +G +D G Sbjct: 1260 VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1319 Query: 1742 TNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAA 1801 V G G A +D V G ED G A P A Sbjct: 1320 PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGA 1379 Query: 1802 RGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKE 1861 G +G E A+G P + G G + G E G A + Sbjct: 1380 AGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQ 1439 Query: 1862 DPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGI 1921 D G + G+ + +G G+ QG E + + + G Sbjct: 1440 DGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG---EKGDRGLPGTQGSPGA 1496 Query: 1922 SKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANE 1978 + + G A G QG + G A + G+ + G E Sbjct: 1497 KGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGE 1553 Score = 84.7 bits (208), Expect = 1e-15 Identities = 195/1024 (19%), Positives = 295/1024 (28%), Gaps = 72/1024 (7%) Query: 1262 GISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEV 1321 G++ G A+G + + QG G + +G D +G+ E Sbjct: 547 GLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEP 606 Query: 1322 EVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIA 1381 +G D + G+ + G G +D + E +G+ E +G+ Sbjct: 607 GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLL 666 Query: 1382 NEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAH 1441 G + G+A D G + QG QG G + Sbjct: 667 GPRGTPGAPGQP---GMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPP 723 Query: 1442 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPD 1501 G G+A A G +G + E G G + D Sbjct: 724 GEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPP---GPQGPIGYPGPRGVKGAD 780 Query: 1502 AARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVV 1561 RG+ +G ED G ++ +G EV G ED +G Sbjct: 781 GVRGLKGSKGEKG------------EDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPK 828 Query: 1562 KEVTAHG---VANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANK 1618 G + + +G + L + + P G E A +A K Sbjct: 829 GRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFP-GANGEKGARGVAGK 887 Query: 1619 DAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGI 1678 +G Q G A G + + +G + D G E QG G Sbjct: 888 PGPRG---QRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP 944 Query: 1679 ANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAA 1738 G G E QG GV V QG E G Sbjct: 945 KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGV---VGPQGPTGETGPIGERGHPGP 1001 Query: 1739 HGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKP 1798 G E G A ++ A+G + QGI+ +D + G+ A + Sbjct: 1002 PGPPGEQGLPGAAGKEGAKG---DPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1058 Query: 1799 DAARGIANEVAA---QGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAA 1855 + +G V + +G A G+P G G E QG A D Sbjct: 1059 EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGV 1118 Query: 1856 QGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANE 1915 QG P+ G+ G ED +G E G + G Sbjct: 1119 QG-----PV-GLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG------------P 1160 Query: 1916 DAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGI 1975 G+ GIA D G + + G ++ A+G G+ QG+ Sbjct: 1161 PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGL------QGL 1214 Query: 1976 ANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVA 2035 +G + G G + A P + G V +G E Sbjct: 1215 PGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGN 1274 Query: 2036 DGIANEDAAHGVANEDAAQAIAKPDAAHGIAN-EGIATEDVADGIAEDA-VQGITNEEAA 2093 G E G E + A P A G +G +D G G Sbjct: 1275 PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1334 Query: 2094 QAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANE 2153 A QD G ED G + G + E G + G A + QG E Sbjct: 1335 PGPAGQDGVGGDKGEDGDPG---QPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQG---E 1388 Query: 2154 VAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGV 2213 A+G A + G V QG A K +G+ G E G A +D G Sbjct: 1389 KGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLR---GIPGPVGEQGLPGAAGQDGPPGP 1445 Query: 2214 ANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAV 2273 G+ + ++G + G+ + E +G+ + G + + Sbjct: 1446 MGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQ---GEKGDRGLPGTQGSPGAKGDGGI 1502 Query: 2274 HGIA 2277 G A Sbjct: 1503 PGPA 1506 Score = 81.6 bits (200), Expect = 8e-15 Identities = 173/978 (17%), Positives = 260/978 (26%), Gaps = 58/978 (5%) Query: 1318 ANEVEVQGVAHEDAV--------QGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQ 1369 A E + Q + + + G+ G A+G + + Q Sbjct: 523 AQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPP 582 Query: 1370 GISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANED 1429 G + + +G D +G+ E +G D + G+ + +G G +D Sbjct: 583 GPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDD 642 Query: 1430 AAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVA 1489 G E+ G+ E +G+ G + + G+ D G + G Sbjct: 643 GMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGV---DGPPGPKGNMGPQGEP 699 Query: 1490 NEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVH 1549 P G + G G+A A G +G + E Sbjct: 700 GPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL 759 Query: 1550 GVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANE 1609 G QG + GV D V+G+ ED G E Sbjct: 760 G---PPGPQGPIGYPGPRGVKGADGVRGLKGSKG----EKGEDGFPGFKGDMGLKGDRGE 812 Query: 1610 VAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGI 1669 V +D +G +G A G S + +G G +G Sbjct: 813 VGQIGPRGEDGPEG------PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGS 866 Query: 1670 AHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAV 1729 G E GVA + G +G +G + +G + D Sbjct: 867 TGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRG---SRGARGPTGKPGPKGTSGGDGP 923 Query: 1730 QGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANE 1789 G E G V G G +D + G + E G Sbjct: 924 PGPPGERGPQGPQGPV---GFPGPKGPPGPPGKDGLPGHPGQRG------ETGFQGKTGP 974 Query: 1790 DAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGI 1849 + P G + +G G P E G A + A G + G Sbjct: 975 PGPGGVVGPQGPTGETGPIGERG---HPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 1031 Query: 1850 ANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAA 1909 +G E + G ++G G G A G+ Sbjct: 1032 DGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGP 1091 Query: 1910 QDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANE 1969 Q +G E QG A +D QG G A G E+ G Sbjct: 1092 QGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGS 1151 Query: 1970 DAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGI---ANEVAA 2026 +G G+ GIA D G + + ARG + Sbjct: 1152 KGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGL 1211 Query: 2027 QGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQG 2086 QG+ G + G + P+ A G + V G+ E G Sbjct: 1212 QGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVG-GVGEKGEPG 1270 Query: 2087 ITNE---EAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVAN 2143 + G E G A+G +D G V G Sbjct: 1271 EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPG 1330 Query: 2144 EDAAQGVANEVAAQGVANED------AVQGVANEVEVQGIAHKDAIQGIANEDAAQGVAN 2197 G A + G ED G + E G K G A + QG Sbjct: 1331 PPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQG--- 1387 Query: 2198 EVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQG 2257 E A G A + G V QG A + +G+ + G E A +D G Sbjct: 1388 EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLR---GIPGPVGEQGLPGAAGQDGPPG 1444 Query: 2258 IANEDAAHGIANEDAVHG 2275 G+ + G Sbjct: 1445 PMGPPGLPGLKGDPGSKG 1462 Score = 75.5 bits (184), Expect = 6e-13 Identities = 192/1044 (18%), Positives = 288/1044 (27%), Gaps = 76/1044 (7%) Query: 67 GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126 G+T G A+G + + G G + +G +G+ E Sbjct: 547 GLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEP 606 Query: 127 AVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIA 186 +G D + G+ + +G G +D +G E + + E + + Sbjct: 607 GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLL 666 Query: 187 NEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQ 246 G + G+A D G QG QG + G + Sbjct: 667 GPRGTPGAPGQ---PGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPP 723 Query: 247 GVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 306 G G+A A G G + E A G QG +G+ D Sbjct: 724 GEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALG---PPGPQGPIGYPGPRGVKGAD 780 Query: 307 AVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVA 366 V G+ + G ED G EV G ED +G G A Sbjct: 781 GVRGLK---GSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEG------PKGRA 831 Query: 367 KEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAA 426 G + + +G + L G + + P G E A G+A + Sbjct: 832 GPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP-GFPGANGEKGARGVAGKPGP 890 Query: 427 QGIANEV------AAHGISKEDAVQGIANEDAAQGIAHEDAAQ------GIAHEDAVQGI 474 +G A G + + +G + D G E Q G G Sbjct: 891 RGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGP 950 Query: 475 ANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAV 534 +D + G + G K +G E G G E + Sbjct: 951 PGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGL 1010 Query: 535 HGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANE 594 G A + A G + I+ D G+ +G+ A G+ + G Sbjct: 1011 PGAAGKEGAKG---DPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGP 1067 Query: 595 VAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGV 654 V G +G A G+ QG G E QG D + G Sbjct: 1068 VGSPG------ERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1121 Query: 655 VANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDA 714 V A P G E+ G +G G+ V A GI+ D Sbjct: 1122 VGLPGPAGPAGSP-GEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDG 1180 Query: 715 VQGIANEDAAQGIAHEDAVQGI---------------ANEDAVHGVAKEVAAHGVANEDP 759 G + G ++ +G E +G + G Sbjct: 1181 EPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRG 1240 Query: 760 VQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVAN 819 QG D QG V G E G A G A GV +G Sbjct: 1241 PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEA------GVGGPKGERGEKG 1294 Query: 820 EDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQ 879 E G A G +D +G V G G ++ + G ED Sbjct: 1295 EAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGG-DKGEDGDP 1353 Query: 880 AIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSI 939 P G + E G + G A A G E+ A+ A + Sbjct: 1354 GQPGP--------PGPSGEAGPPGPPGKRGPPGAA--GAEGRQGEKGAKGEAGAEGPPGK 1403 Query: 940 TNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEV 999 T QG A + G+ G E G A +D G + G+ + Sbjct: 1404 TGPVGPQGPAGKPGPEGLR---GIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGS 1460 Query: 1000 QGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKE 1059 +G + G+ G E G+ + G + G A + G Sbjct: 1461 KGEKGHPGLIGLIGPPGEQG---EKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL 1517 Query: 1060 DAVQGIANEDAAQGIANEDAAQGI 1083 QG + G A + G+ Sbjct: 1518 PGPQGPKGNKGSTGPAGQKGDSGL 1541 >gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo sapiens] Length = 1767 Score = 99.8 bits (247), Expect = 3e-20 Identities = 204/1077 (18%), Positives = 301/1077 (27%), Gaps = 68/1077 (6%) Query: 923 KEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVH 982 +E AQAI +Q A ++ G+ G A+G + + QG Sbjct: 473 QEAQAQAILQQ-ARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPP 531 Query: 983 GVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANED 1042 G + +G +G+ + +G D G+ + G G +D Sbjct: 532 GPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDD 591 Query: 1043 AAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVA 1102 +G E+ G+ E +G+ G + G+A D G Sbjct: 592 GMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQ------------PGMAGVDGPPGPK 639 Query: 1103 KEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAH 1162 + G QG + G + G G+A A G Sbjct: 640 GNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKE 699 Query: 1163 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPD 1222 G + E A G QG +G+ D V G+ + G ED Sbjct: 700 GQSGEKGALG---PPGPQGPIGYPGPRGVKGADGVRGLK---GSKGEKGEDGFPGFKGDM 753 Query: 1223 AARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIA 1282 +G EV G ED +G G G + V G+ QG Sbjct: 754 GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 813 Query: 1283 KEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAH 1342 G + +G +GVA + +G +G +G + Sbjct: 814 GSTGFPGFPGANGEKG------ARGVAGKPGPRGQRGPTGPRG---SRGARGPTGKPGPK 864 Query: 1343 GIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANED 1402 G + D G E Q G G +D G + G + Sbjct: 865 GTSGGDGPPGPPGERGPQ---GPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKT 921 Query: 1403 AVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIA 1462 G V QG E G G E G A ++ A+G + QGI+ Sbjct: 922 GPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKG---DPGPQGIS 978 Query: 1463 HEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVAD 1522 +D G+ G+ A G+ + P + G T G Sbjct: 979 GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAG------PI 1032 Query: 1523 GIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVA---NEDAVQGVV 1579 G+ G +G E G A D VQG V G A ED +G + Sbjct: 1033 GLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEI 1092 Query: 1580 NEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAA 1639 E ++ P G+ V A IA D G Q G + A Sbjct: 1093 GEPGQKGSKGDKGE----NGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGA 1148 Query: 1640 HGISKEDAVQGIANEDAAQGIANED---------------AAQGIAHEDAVQG-IANEDA 1683 G G+ G E+ QG D QG + + Sbjct: 1149 RGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGS 1208 Query: 1684 VHGVAKEVAAHGVANEDP--VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGI 1741 V GV ++ N P GV +G E G A +G +D G Sbjct: 1209 VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1268 Query: 1742 TNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAA 1801 V G G A +D V G ED G A P A Sbjct: 1269 PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGA 1328 Query: 1802 RGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKE 1861 G +G E A+G P + G G + G E G A + Sbjct: 1329 AGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQ 1388 Query: 1862 DPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGI 1921 D G + G+ + +G G+ QG E + + + G Sbjct: 1389 DGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG---EKGDRGLPGTQGSPGA 1445 Query: 1922 SKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANE 1978 + + G A G QG + G A + G+ + G E Sbjct: 1446 KGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGE 1502 Score = 84.7 bits (208), Expect = 1e-15 Identities = 195/1024 (19%), Positives = 295/1024 (28%), Gaps = 72/1024 (7%) Query: 1262 GISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEV 1321 G++ G A+G + + QG G + +G D +G+ E Sbjct: 496 GLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEP 555 Query: 1322 EVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIA 1381 +G D + G+ + G G +D + E +G+ E +G+ Sbjct: 556 GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLL 615 Query: 1382 NEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAH 1441 G + G+A D G + QG QG G + Sbjct: 616 GPRGTPGAPGQP---GMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPP 672 Query: 1442 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPD 1501 G G+A A G +G + E G G + D Sbjct: 673 GEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPP---GPQGPIGYPGPRGVKGAD 729 Query: 1502 AARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVV 1561 RG+ +G ED G ++ +G EV G ED +G Sbjct: 730 GVRGLKGSKGEKG------------EDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPK 777 Query: 1562 KEVTAHG---VANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANK 1618 G + + +G + L + + P G E A +A K Sbjct: 778 GRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFP-GANGEKGARGVAGK 836 Query: 1619 DAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGI 1678 +G Q G A G + + +G + D G E QG G Sbjct: 837 PGPRG---QRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP 893 Query: 1679 ANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAA 1738 G G E QG GV V QG E G Sbjct: 894 KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGV---VGPQGPTGETGPIGERGHPGP 950 Query: 1739 HGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKP 1798 G E G A ++ A+G + QGI+ +D + G+ A + Sbjct: 951 PGPPGEQGLPGAAGKEGAKG---DPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1007 Query: 1799 DAARGIANEVAA---QGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAA 1855 + +G V + +G A G+P G G E QG A D Sbjct: 1008 EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGV 1067 Query: 1856 QGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANE 1915 QG P+ G+ G ED +G E G + G Sbjct: 1068 QG-----PV-GLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG------------P 1109 Query: 1916 DAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGI 1975 G+ GIA D G + + G ++ A+G G+ QG+ Sbjct: 1110 PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGL------QGL 1163 Query: 1976 ANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVA 2035 +G + G G + A P + G V +G E Sbjct: 1164 PGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGN 1223 Query: 2036 DGIANEDAAHGVANEDAAQAIAKPDAAHGIAN-EGIATEDVADGIAEDA-VQGITNEEAA 2093 G E G E + A P A G +G +D G G Sbjct: 1224 PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1283 Query: 2094 QAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANE 2153 A QD G ED G + G + E G + G A + QG E Sbjct: 1284 PGPAGQDGVGGDKGEDGDPG---QPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQG---E 1337 Query: 2154 VAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGV 2213 A+G A + G V QG A K +G+ G E G A +D G Sbjct: 1338 KGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLR---GIPGPVGEQGLPGAAGQDGPPGP 1394 Query: 2214 ANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAV 2273 G+ + ++G + G+ + E +G+ + G + + Sbjct: 1395 MGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQ---GEKGDRGLPGTQGSPGAKGDGGI 1451 Query: 2274 HGIA 2277 G A Sbjct: 1452 PGPA 1455 Score = 81.6 bits (200), Expect = 8e-15 Identities = 173/978 (17%), Positives = 260/978 (26%), Gaps = 58/978 (5%) Query: 1318 ANEVEVQGVAHEDAV--------QGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQ 1369 A E + Q + + + G+ G A+G + + Q Sbjct: 472 AQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPP 531 Query: 1370 GISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANED 1429 G + + +G D +G+ E +G D + G+ + +G G +D Sbjct: 532 GPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDD 591 Query: 1430 AAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVA 1489 G E+ G+ E +G+ G + + G+ D G + G Sbjct: 592 GMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGV---DGPPGPKGNMGPQGEP 648 Query: 1490 NEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVH 1549 P G + G G+A A G +G + E Sbjct: 649 GPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL 708 Query: 1550 GVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANE 1609 G QG + GV D V+G+ ED G E Sbjct: 709 G---PPGPQGPIGYPGPRGVKGADGVRGLKGSKG----EKGEDGFPGFKGDMGLKGDRGE 761 Query: 1610 VAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGI 1669 V +D +G +G A G S + +G G +G Sbjct: 762 VGQIGPRGEDGPEG------PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGS 815 Query: 1670 AHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAV 1729 G E GVA + G +G +G + +G + D Sbjct: 816 TGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRG---SRGARGPTGKPGPKGTSGGDGP 872 Query: 1730 QGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANE 1789 G E G V G G +D + G + E G Sbjct: 873 PGPPGERGPQGPQGPV---GFPGPKGPPGPPGKDGLPGHPGQRG------ETGFQGKTGP 923 Query: 1790 DAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGI 1849 + P G + +G G P E G A + A G + G Sbjct: 924 PGPGGVVGPQGPTGETGPIGERG---HPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 980 Query: 1850 ANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAA 1909 +G E + G ++G G G A G+ Sbjct: 981 DGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGP 1040 Query: 1910 QDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANE 1969 Q +G E QG A +D QG G A G E+ G Sbjct: 1041 QGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGS 1100 Query: 1970 DAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGI---ANEVAA 2026 +G G+ GIA D G + + ARG + Sbjct: 1101 KGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGL 1160 Query: 2027 QGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQG 2086 QG+ G + G + P+ A G + V G+ E G Sbjct: 1161 QGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVG-GVGEKGEPG 1219 Query: 2087 ITNE---EAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVAN 2143 + G E G A+G +D G V G Sbjct: 1220 EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPG 1279 Query: 2144 EDAAQGVANEVAAQGVANED------AVQGVANEVEVQGIAHKDAIQGIANEDAAQGVAN 2197 G A + G ED G + E G K G A + QG Sbjct: 1280 PPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQG--- 1336 Query: 2198 EVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQG 2257 E A G A + G V QG A + +G+ + G E A +D G Sbjct: 1337 EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLR---GIPGPVGEQGLPGAAGQDGPPG 1393 Query: 2258 IANEDAAHGIANEDAVHG 2275 G+ + G Sbjct: 1394 PMGPPGLPGLKGDPGSKG 1411 Score = 75.5 bits (184), Expect = 6e-13 Identities = 192/1044 (18%), Positives = 288/1044 (27%), Gaps = 76/1044 (7%) Query: 67 GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126 G+T G A+G + + G G + +G +G+ E Sbjct: 496 GLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEP 555 Query: 127 AVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIA 186 +G D + G+ + +G G +D +G E + + E + + Sbjct: 556 GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLL 615 Query: 187 NEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQ 246 G + G+A D G QG QG + G + Sbjct: 616 GPRGTPGAPGQ---PGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPP 672 Query: 247 GVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 306 G G+A A G G + E A G QG +G+ D Sbjct: 673 GEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALG---PPGPQGPIGYPGPRGVKGAD 729 Query: 307 AVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVA 366 V G+ + G ED G EV G ED +G G A Sbjct: 730 GVRGLK---GSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEG------PKGRA 780 Query: 367 KEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAA 426 G + + +G + L G + + P G E A G+A + Sbjct: 781 GPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP-GFPGANGEKGARGVAGKPGP 839 Query: 427 QGIANEV------AAHGISKEDAVQGIANEDAAQGIAHEDAAQ------GIAHEDAVQGI 474 +G A G + + +G + D G E Q G G Sbjct: 840 RGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGP 899 Query: 475 ANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAV 534 +D + G + G K +G E G G E + Sbjct: 900 PGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGL 959 Query: 535 HGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANE 594 G A + A G + I+ D G+ +G+ A G+ + G Sbjct: 960 PGAAGKEGAKG---DPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGP 1016 Query: 595 VAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGV 654 V G +G A G+ QG G E QG D + G Sbjct: 1017 VGSPG------ERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1070 Query: 655 VANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDA 714 V A P G E+ G +G G+ V A GI+ D Sbjct: 1071 VGLPGPAGPAGSP-GEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDG 1129 Query: 715 VQGIANEDAAQGIAHEDAVQGI---------------ANEDAVHGVAKEVAAHGVANEDP 759 G + G ++ +G E +G + G Sbjct: 1130 EPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRG 1189 Query: 760 VQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVAN 819 QG D QG V G E G A G A GV +G Sbjct: 1190 PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEA------GVGGPKGERGEKG 1243 Query: 820 EDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQ 879 E G A G +D +G V G G ++ + G ED Sbjct: 1244 EAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGG-DKGEDGDP 1302 Query: 880 AIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSI 939 P G + E G + G A A G E+ A+ A + Sbjct: 1303 GQPGP--------PGPSGEAGPPGPPGKRGPPGAA--GAEGRQGEKGAKGEAGAEGPPGK 1352 Query: 940 TNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEV 999 T QG A + G+ G E G A +D G + G+ + Sbjct: 1353 TGPVGPQGPAGKPGPEGLR---GIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGS 1409 Query: 1000 QGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKE 1059 +G + G+ G E G+ + G + G A + G Sbjct: 1410 KGEKGHPGLIGLIGPPGEQG---EKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL 1466 Query: 1060 DAVQGIANEDAAQGIANEDAAQGI 1083 QG + G A + G+ Sbjct: 1467 PGPQGPKGNKGSTGPAGQKGDSGL 1490 >gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo sapiens] Length = 1806 Score = 99.8 bits (247), Expect = 3e-20 Identities = 204/1077 (18%), Positives = 301/1077 (27%), Gaps = 68/1077 (6%) Query: 923 KEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVH 982 +E AQAI +Q A ++ G+ G A+G + + QG Sbjct: 512 QEAQAQAILQQ-ARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPP 570 Query: 983 GVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANED 1042 G + +G +G+ + +G D G+ + G G +D Sbjct: 571 GPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDD 630 Query: 1043 AAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVA 1102 +G E+ G+ E +G+ G + G+A D G Sbjct: 631 GMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQ------------PGMAGVDGPPGPK 678 Query: 1103 KEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAH 1162 + G QG + G + G G+A A G Sbjct: 679 GNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKE 738 Query: 1163 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPD 1222 G + E A G QG +G+ D V G+ + G ED Sbjct: 739 GQSGEKGALG---PPGPQGPIGYPGPRGVKGADGVRGLK---GSKGEKGEDGFPGFKGDM 792 Query: 1223 AARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIA 1282 +G EV G ED +G G G + V G+ QG Sbjct: 793 GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPK 852 Query: 1283 KEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAH 1342 G + +G +GVA + +G +G +G + Sbjct: 853 GSTGFPGFPGANGEKG------ARGVAGKPGPRGQRGPTGPRG---SRGARGPTGKPGPK 903 Query: 1343 GIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANED 1402 G + D G E Q G G +D G + G + Sbjct: 904 GTSGGDGPPGPPGERGPQ---GPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKT 960 Query: 1403 AVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIA 1462 G V QG E G G E G A ++ A+G + QGI+ Sbjct: 961 GPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKG---DPGPQGIS 1017 Query: 1463 HEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVAD 1522 +D G+ G+ A G+ + P + G T G Sbjct: 1018 GKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAG------PI 1071 Query: 1523 GIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVA---NEDAVQGVV 1579 G+ G +G E G A D VQG V G A ED +G + Sbjct: 1072 GLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEI 1131 Query: 1580 NEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAA 1639 E ++ P G+ V A IA D G Q G + A Sbjct: 1132 GEPGQKGSKGDKGE----NGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGA 1187 Query: 1640 HGISKEDAVQGIANEDAAQGIANED---------------AAQGIAHEDAVQG-IANEDA 1683 G G+ G E+ QG D QG + + Sbjct: 1188 RGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGS 1247 Query: 1684 VHGVAKEVAAHGVANEDP--VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGI 1741 V GV ++ N P GV +G E G A +G +D G Sbjct: 1248 VGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN 1307 Query: 1742 TNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAA 1801 V G G A +D V G ED G A P A Sbjct: 1308 PGPVGFPGDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGA 1367 Query: 1802 RGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKE 1861 G +G E A+G P + G G + G E G A + Sbjct: 1368 AGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQ 1427 Query: 1862 DPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGI 1921 D G + G+ + +G G+ QG E + + + G Sbjct: 1428 DGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQG---EKGDRGLPGTQGSPGA 1484 Query: 1922 SKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANE 1978 + + G A G QG + G A + G+ + G E Sbjct: 1485 KGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGE 1541 Score = 84.7 bits (208), Expect = 1e-15 Identities = 195/1024 (19%), Positives = 295/1024 (28%), Gaps = 72/1024 (7%) Query: 1262 GISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEV 1321 G++ G A+G + + QG G + +G D +G+ E Sbjct: 535 GLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEP 594 Query: 1322 EVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIA 1381 +G D + G+ + G G +D + E +G+ E +G+ Sbjct: 595 GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLL 654 Query: 1382 NEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAH 1441 G + G+A D G + QG QG G + Sbjct: 655 GPRGTPGAPGQP---GMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPP 711 Query: 1442 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPD 1501 G G+A A G +G + E G G + D Sbjct: 712 GEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPP---GPQGPIGYPGPRGVKGAD 768 Query: 1502 AARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVV 1561 RG+ +G ED G ++ +G EV G ED +G Sbjct: 769 GVRGLKGSKGEKG------------EDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEGPK 816 Query: 1562 KEVTAHG---VANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANK 1618 G + + +G + L + + P G E A +A K Sbjct: 817 GRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFP-GANGEKGARGVAGK 875 Query: 1619 DAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGI 1678 +G Q G A G + + +G + D G E QG G Sbjct: 876 PGPRG---QRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGP 932 Query: 1679 ANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAA 1738 G G E QG GV V QG E G Sbjct: 933 KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGV---VGPQGPTGETGPIGERGHPGP 989 Query: 1739 HGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKP 1798 G E G A ++ A+G + QGI+ +D + G+ A + Sbjct: 990 PGPPGEQGLPGAAGKEGAKG---DPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGG 1046 Query: 1799 DAARGIANEVAA---QGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAA 1855 + +G V + +G A G+P G G E QG A D Sbjct: 1047 EGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGV 1106 Query: 1856 QGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANE 1915 QG P+ G+ G ED +G E G + G Sbjct: 1107 QG-----PV-GLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENG------------P 1148 Query: 1916 DAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGI 1975 G+ GIA D G + + G ++ A+G G+ QG+ Sbjct: 1149 PGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGL------QGL 1202 Query: 1976 ANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVA 2035 +G + G G + A P + G V +G E Sbjct: 1203 PGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGN 1262 Query: 2036 DGIANEDAAHGVANEDAAQAIAKPDAAHGIAN-EGIATEDVADGIAEDA-VQGITNEEAA 2093 G E G E + A P A G +G +D G G Sbjct: 1263 PGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGE 1322 Query: 2094 QAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANE 2153 A QD G ED G + G + E G + G A + QG E Sbjct: 1323 PGPAGQDGVGGDKGEDGDPG---QPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQG---E 1376 Query: 2154 VAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGV 2213 A+G A + G V QG A K +G+ G E G A +D G Sbjct: 1377 KGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLR---GIPGPVGEQGLPGAAGQDGPPGP 1433 Query: 2214 ANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAV 2273 G+ + ++G + G+ + E +G+ + G + + Sbjct: 1434 MGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQ---GEKGDRGLPGTQGSPGAKGDGGI 1490 Query: 2274 HGIA 2277 G A Sbjct: 1491 PGPA 1494 Score = 81.6 bits (200), Expect = 8e-15 Identities = 173/978 (17%), Positives = 260/978 (26%), Gaps = 58/978 (5%) Query: 1318 ANEVEVQGVAHEDAV--------QGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQ 1369 A E + Q + + + G+ G A+G + + Q Sbjct: 511 AQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPP 570 Query: 1370 GISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANED 1429 G + + +G D +G+ E +G D + G+ + +G G +D Sbjct: 571 GPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDD 630 Query: 1430 AAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVA 1489 G E+ G+ E +G+ G + + G+ D G + G Sbjct: 631 GMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGV---DGPPGPKGNMGPQGEP 687 Query: 1490 NEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVH 1549 P G + G G+A A G +G + E Sbjct: 688 GPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGAL 747 Query: 1550 GVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANE 1609 G QG + GV D V+G+ ED G E Sbjct: 748 G---PPGPQGPIGYPGPRGVKGADGVRGLKGSKG----EKGEDGFPGFKGDMGLKGDRGE 800 Query: 1610 VAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGI 1669 V +D +G +G A G S + +G G +G Sbjct: 801 VGQIGPRGEDGPEG------PKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGS 854 Query: 1670 AHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAV 1729 G E GVA + G +G +G + +G + D Sbjct: 855 TGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRG---SRGARGPTGKPGPKGTSGGDGP 911 Query: 1730 QGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANE 1789 G E G V G G +D + G + E G Sbjct: 912 PGPPGERGPQGPQGPV---GFPGPKGPPGPPGKDGLPGHPGQRG------ETGFQGKTGP 962 Query: 1790 DAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGI 1849 + P G + +G G P E G A + A G + G Sbjct: 963 PGPGGVVGPQGPTGETGPIGERG---HPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGK 1019 Query: 1850 ANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAA 1909 +G E + G ++G G G A G+ Sbjct: 1020 DGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGP 1079 Query: 1910 QDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANE 1969 Q +G E QG A +D QG G A G E+ G Sbjct: 1080 QGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGS 1139 Query: 1970 DAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGI---ANEVAA 2026 +G G+ GIA D G + + ARG + Sbjct: 1140 KGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGL 1199 Query: 2027 QGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQG 2086 QG+ G + G + P+ A G + V G+ E G Sbjct: 1200 QGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVG-GVGEKGEPG 1258 Query: 2087 ITNE---EAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVAN 2143 + G E G A+G +D G V G Sbjct: 1259 EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPG 1318 Query: 2144 EDAAQGVANEVAAQGVANED------AVQGVANEVEVQGIAHKDAIQGIANEDAAQGVAN 2197 G A + G ED G + E G K G A + QG Sbjct: 1319 PPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQG--- 1375 Query: 2198 EVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQG 2257 E A G A + G V QG A + +G+ + G E A +D G Sbjct: 1376 EKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLR---GIPGPVGEQGLPGAAGQDGPPG 1432 Query: 2258 IANEDAAHGIANEDAVHG 2275 G+ + G Sbjct: 1433 PMGPPGLPGLKGDPGSKG 1450 Score = 75.5 bits (184), Expect = 6e-13 Identities = 192/1044 (18%), Positives = 288/1044 (27%), Gaps = 76/1044 (7%) Query: 67 GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126 G+T G A+G + + G G + +G +G+ E Sbjct: 535 GLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEP 594 Query: 127 AVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIA 186 +G D + G+ + +G G +D +G E + + E + + Sbjct: 595 GAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLL 654 Query: 187 NEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQ 246 G + G+A D G QG QG + G + Sbjct: 655 GPRGTPGAPGQ---PGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPP 711 Query: 247 GVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 306 G G+A A G G + E A G QG +G+ D Sbjct: 712 GEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALG---PPGPQGPIGYPGPRGVKGAD 768 Query: 307 AVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVA 366 V G+ + G ED G EV G ED +G G A Sbjct: 769 GVRGLK---GSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPEG------PKGRA 819 Query: 367 KEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAA 426 G + + +G + L G + + P G E A G+A + Sbjct: 820 GPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFP-GFPGANGEKGARGVAGKPGP 878 Query: 427 QGIANEV------AAHGISKEDAVQGIANEDAAQGIAHEDAAQ------GIAHEDAVQGI 474 +G A G + + +G + D G E Q G G Sbjct: 879 RGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGP 938 Query: 475 ANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAV 534 +D + G + G K +G E G G E + Sbjct: 939 PGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGL 998 Query: 535 HGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANE 594 G A + A G + I+ D G+ +G+ A G+ + G Sbjct: 999 PGAAGKEGAKG---DPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGP 1055 Query: 595 VAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGV 654 V G +G A G+ QG G E QG D + G Sbjct: 1056 VGSPG------ERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGP 1109 Query: 655 VANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDA 714 V A P G E+ G +G G+ V A GI+ D Sbjct: 1110 VGLPGPAGPAGSP-GEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDG 1168 Query: 715 VQGIANEDAAQGIAHEDAVQGI---------------ANEDAVHGVAKEVAAHGVANEDP 759 G + G ++ +G E +G + G Sbjct: 1169 EPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRG 1228 Query: 760 VQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVAN 819 QG D QG V G E G A G A GV +G Sbjct: 1229 PQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEA------GVGGPKGERGEKG 1282 Query: 820 EDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQ 879 E G A G +D +G V G G ++ + G ED Sbjct: 1283 EAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPGEPGPAGQDGVGG-DKGEDGDP 1341 Query: 880 AIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSI 939 P G + E G + G A A G E+ A+ A + Sbjct: 1342 GQPGP--------PGPSGEAGPPGPPGKRGPPGAA--GAEGRQGEKGAKGEAGAEGPPGK 1391 Query: 940 TNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEV 999 T QG A + G+ G E G A +D G + G+ + Sbjct: 1392 TGPVGPQGPAGKPGPEGLR---GIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGS 1448 Query: 1000 QGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKE 1059 +G + G+ G E G+ + G + G A + G Sbjct: 1449 KGEKGHPGLIGLIGPPGEQG---EKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGL 1505 Query: 1060 DAVQGIANEDAAQGIANEDAAQGI 1083 QG + G A + G+ Sbjct: 1506 PGPQGPKGNKGSTGPAGQKGDSGL 1529 >gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo sapiens] Length = 1629 Score = 98.6 bits (244), Expect = 6e-20 Identities = 174/919 (18%), Positives = 253/919 (27%), Gaps = 55/919 (5%) Query: 1116 VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIAN 1175 ++G + + QG + G + +G A D A G+ + G D G+ Sbjct: 402 LKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPG 461 Query: 1176 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQG 1235 E +G + G ED G E+ G+ E + P GI +G Sbjct: 462 EKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRG 521 Query: 1236 IATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDA 1295 + G G + G QG +G + + G+ D Sbjct: 522 MDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG 581 Query: 1296 AQG-IAKEDPVQGVANEDPI--QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQG 1352 G KE P N+ P QG +GV D ++G+ +G Sbjct: 582 PPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH------------KG 629 Query: 1353 IANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVE 1412 ED + +G E V G ED +G G + G ++ Sbjct: 630 EKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLG 689 Query: 1413 VQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIAN 1472 V G + G G G + E A+G++ + +G E G Sbjct: 690 VPG------LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG---ERGPTGPRG 740 Query: 1473 EDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHG 1532 + G + A G + D H P RG+ G G +D G Sbjct: 741 QRGPRGATGKSGAKGTSGGDGPHG---PPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPG 797 Query: 1533 VANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANED 1592 + G + G QG E G G E L A ++ Sbjct: 798 HPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPG-TAGKE 856 Query: 1593 AAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQ--- 1649 + P A G KD G+ +G+ G+ + Sbjct: 857 GTKGDPGPPGAPG------------KDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPP 904 Query: 1650 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANED 1709 G A +G A G QG GV E G D VQG Sbjct: 905 GPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPV--- 961 Query: 1710 AVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIA 1769 G+ GVA ED +G + G HG G + G Sbjct: 962 ---GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGAD 1018 Query: 1770 NEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAH 1829 E A G + P +G+ +G + G P Sbjct: 1019 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1078 Query: 1830 GVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANED 1889 G A A G G +G E G+ E V+G E +G E Sbjct: 1079 GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGE---RGEKGES 1135 Query: 1890 AAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIA 1949 G +G +D + G G QD A+G ED G Sbjct: 1136 GQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG-- 1193 Query: 1950 NEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAH 2009 + + G E G + G + QG G G Sbjct: 1194 -QPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPA 1252 Query: 2010 AIAKPDAARGIANEVAAQG 2028 PD RG+ V QG Sbjct: 1253 GKPGPDGLRGLPGSVGQQG 1271 Score = 94.7 bits (234), Expect = 9e-19 Identities = 191/1067 (17%), Positives = 289/1067 (27%), Gaps = 62/1067 (5%) Query: 923 KEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVH 982 +E AQAI +Q A ++ G G +G + ++ QG + Sbjct: 363 QEAQAQAILQQ-ARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLT 421 Query: 983 GVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANED 1042 G + +G A +G+ ++G D G+ E G G ED Sbjct: 422 GPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED 481 Query: 1043 AAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVA 1102 +G E+ G+ E +G+ GI +G+ +G G Sbjct: 482 GERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPP 541 Query: 1103 KEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAA- 1161 + G QG +G + + G+ D G ++ G Sbjct: 542 GQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPS 601 Query: 1162 -----------HGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVA 1210 G+ D +G+ +G ED G + V G EV G Sbjct: 602 GPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG---EDGFPGFKGDIGVKGDRGEVGVPGSR 658 Query: 1211 NEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQ 1270 ED P+ +G G G+ E GV + Sbjct: 659 GEDG------PEGPKGRTGPTGDPG------PPGLMGEKGKLGV------------PGLP 694 Query: 1271 GIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHED 1330 G +G G + E A+G++ + G E G + +G + Sbjct: 695 GYPGRQGPKGSLGFPGFPGASGEKGARGLSGK---SGPRGERGPTGPRGQRGPRGATGKS 751 Query: 1331 AVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIA 1390 +G + D HG E +G+ G +D + G + G Sbjct: 752 GAKGTSGGDGPHGPPGE---RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQ 808 Query: 1391 KEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQ 1450 + G QG A E G G E G A + G A Sbjct: 809 GKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAP 868 Query: 1451 GIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEV 1510 G +G E + G A + G G A A G Sbjct: 869 GKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP 928 Query: 1511 ATQGIATEDVADGIANEDAAHGVANEVAAQ---GIANEVAVHGVAIEDAVQGVVKEVTAH 1567 QG G+ E G Q G+ GVA ED +G V + Sbjct: 929 GPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQK 988 Query: 1568 GVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQ 1627 G G V AA A +P A G A G Sbjct: 989 GTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEP-GARGPQGHFGAKGDEGTRGFNGPPGP 1047 Query: 1628 DAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1687 QG+ G + + G +G A + A G G G Sbjct: 1048 IGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1107 Query: 1688 AKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAA 1747 E + G+ E V+G E +G + + G +G +D G V Sbjct: 1108 PGESGSPGIQGEPGVKGPRGERGEKGESGQ---PGEPGPPGPKGPTGDDGPKGNPGPVGF 1164 Query: 1748 HGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANE 1807 G G +D +G ED E G + P RG A Sbjct: 1165 PGDPGPPGEGGPRGQDGAKGDRGEDG------EPGQPGSPGPTGENGPPGPLGKRGPAGS 1218 Query: 1808 VAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGV 1867 ++G A G P A G V G + + G+ + G + G Sbjct: 1219 PGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVG---QQGRPGA 1275 Query: 1868 ANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAV 1927 + G + G+ + A G G+ Q + G Sbjct: 1276 TGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQ 1335 Query: 1928 QGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQG 1974 +G A G G+ +G G E QG Sbjct: 1336 KGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQG 1382 Score = 94.7 bits (234), Expect = 9e-19 Identities = 173/939 (18%), Positives = 255/939 (27%), Gaps = 28/939 (2%) Query: 62 ADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQG 121 AD A G+ + V+G G+ E G G ED +G E+ +G Sbjct: 435 ADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRG 494 Query: 122 VANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDA 181 + E +G+ G+ V+G+ G G + Sbjct: 495 LPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPG 554 Query: 182 AQDIANEDAAQGISKEDAVQGIANEDAAQG-IAKEDPVQGVANEDP--VQGVANEDAVQG 238 Q +G + + G+ D G KE P N+ P QG +G Sbjct: 555 PQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRG 614 Query: 239 VANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDA 298 V V G+ +G ED G ++ G E G ED +G Sbjct: 615 VKG---VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTG 671 Query: 299 VQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIAN 358 G + G ++ G+ G +G G Sbjct: 672 PTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG 731 Query: 359 EDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAH 418 E G + G + +G D HG + + P +G Sbjct: 732 ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHG----PPGERGLPGPQGPNGFPGPKGPP 787 Query: 419 GIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANED 478 G +D G + G + G QG A E G G E Sbjct: 788 GPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQ 847 Query: 479 AVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVA 538 + G A + G A P RG E G A G G A Sbjct: 848 GLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPA 907 Query: 539 NEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVH 598 G A G +G+ E G D GV V + Sbjct: 908 GSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRD---GVQGPVGLP 964 Query: 599 GVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANE 658 G A GVA ED G + +G HG G V + G E Sbjct: 965 GPA---GPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAG-ADGE 1020 Query: 659 DAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGI 718 A+ A G +G QG+ +G +V G +G Sbjct: 1021 PGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGP 1080 Query: 719 ANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEV 778 A + A G G G E + G+ E V+G E +G E Sbjct: 1081 AGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGE---RGEKGESGQ 1137 Query: 779 QGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANE 838 G +G +D G V G G +D A+G ED G + Sbjct: 1138 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGED---GEPGQ 1194 Query: 839 DAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANE 898 + G E G + G E G + AI P + G A + Sbjct: 1195 PGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1254 Query: 899 VAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVA 958 G+ + + + G T + + + A+G G+ Sbjct: 1255 PGPDGL--RGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLI 1312 Query: 959 NEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEV 997 QG E +G+ G E + G + + Sbjct: 1313 GPPGEQG---EKGDRGLPGPQGSPGQKGEMGIPGASGPI 1348 Score = 90.9 bits (224), Expect = 1e-17 Identities = 195/1042 (18%), Positives = 294/1042 (28%), Gaps = 72/1042 (6%) Query: 392 VVANEDAAQAIAK--------PDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDA 443 V A E AQAI + P G G +G + ++ G Sbjct: 360 VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQG 419 Query: 444 VQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAK 503 + G + +G A D A+G+ + V+G D + G+ E G Sbjct: 420 LTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 479 Query: 504 PDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHG 563 D RG E+ +G+ E G+ G+ G+ P G Sbjct: 480 EDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPG 539 Query: 564 IANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANE-- 621 + T G G G + + G+ D G ++ G Sbjct: 540 PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQG 599 Query: 622 -DAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAH 680 QG GV D ++G+ G ED G EV Sbjct: 600 PSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG----EDGFPGFKGDIGVKGDRGEVGVP 655 Query: 681 GIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANED 740 G ED +G G G + V G+ QG +G Sbjct: 656 GSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQG------PKGSLGFP 709 Query: 741 AVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIA 800 G + E A G++ + G E G + +G + +G + D HG Sbjct: 710 GFPGASGEKGARGLSGK---SGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPP 766 Query: 801 NEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQ 860 E G+ G G +D + G G EV G T Sbjct: 767 GE---RGLPGPQGPNGFPGPKGPPGPPGKDGLPG------HPGQRGEVGFQGKTGPPGPP 817 Query: 861 GVVNEEALHGVVA--NEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAA 918 GVV + G E P G+ G A + +G A G KD Sbjct: 818 GVVGPQGAAGETGPMGERGHPGPPGPPGEQGL--PGTAGKEGTKGDPGPPGAPG--KDGP 873 Query: 919 HGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANE 978 G+ + + + + G + G E A G + G Sbjct: 874 AGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPG---ERGAAGSGGPIGPPGRPGP 930 Query: 979 DAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGI 1038 G A E V G + G +D +QG G+ G+A ED +G Sbjct: 931 QGPPGAAGEKGVPGEKGPI---GPTGRDGVQGPV------GLPGPAGPPGVAGEDGDKGE 981 Query: 1039 ANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAV 1098 + +G HG G + A G E A+G +G ++ Sbjct: 982 VGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKG---DEGT 1038 Query: 1099 HGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANE 1158 G +G +QG+ +G +V G +G A + A G Sbjct: 1039 RGF------NGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGP 1092 Query: 1159 VAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAI 1218 G +G E + GI E V+G E G E G Sbjct: 1093 PGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGE---RGEKGESGQPGEPGPPGPKGP 1149 Query: 1219 AKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAA 1278 D +G V G G +D A G E G + G E+ Sbjct: 1150 TGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG---QPGSPGPTGENGP 1206 Query: 1279 QGIAKEDAVQGIANEDAAQG--IAKEDP-VQGVANEDPIQGVANEVEVQGVAHEDAVQGI 1335 G + G + QG AK DP G + G A G + G Sbjct: 1207 PGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGS 1266 Query: 1336 ANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPV 1395 + G + G + + A+G + G+ QG E Sbjct: 1267 VGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQG---EKGD 1323 Query: 1396 QGVANEDAVQGVANEVEVQGVA 1417 +G+ G E+ + G + Sbjct: 1324 RGLPGPQGSPGQKGEMGIPGAS 1345 Score = 90.5 bits (223), Expect = 2e-17 Identities = 190/1017 (18%), Positives = 273/1017 (26%), Gaps = 73/1017 (7%) Query: 916 DAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGV 975 D A G+ + + D + E +G G ED +G E+ +G+ Sbjct: 436 DGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGL 495 Query: 976 ANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAA 1035 E G+ G+ V+G+ +G G + G Sbjct: 496 PGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGP 555 Query: 1036 QGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANE 1095 QG +G + G+ D G ++ G G G Sbjct: 556 QGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGV 615 Query: 1096 DAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGI 1155 V G+ G ED G + V+G EV V G ED +G G Sbjct: 616 KGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEG---PKGRTGP 672 Query: 1156 ANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAA 1215 + G+ E G+ G +G G + E A G++ + Sbjct: 673 TGDPGPPGLMGEKGKLGV---PGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGP 729 Query: 1216 HAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANE 1275 P RG + +G + A G + D HG E G+ G Sbjct: 730 RGERGPTGPRG---QRGPRGATGKSGAKGTSGGDGPHGPPGE---RGLPGPQGPNGFPGP 783 Query: 1276 DAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGI 1335 G +D + G + G + G QG A E G G Sbjct: 784 KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGP 843 Query: 1336 ANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPV 1395 E G A ++ +G A +G E + G A +G Sbjct: 844 PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP 903 Query: 1396 QGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANE 1455 G A +G A G QG G+ E G D QG Sbjct: 904 PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQG---- 959 Query: 1456 DAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGI 1515 G+ G+A ED G + G H P G + G Sbjct: 960 --PVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAG- 1016 Query: 1516 ATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAV 1575 ADG E A G A+G +G +QG+ G + E Sbjct: 1017 -----ADG---EPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGL------PGPSGEKGE 1062 Query: 1576 QGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIAN 1635 G V P G A A G +G Sbjct: 1063 TGDV-------------GPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG 1109 Query: 1636 EVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHG 1695 E + GI E V+G E +G E G +G +D G V G Sbjct: 1110 ESGSPGIQGEPGVKGPRGERGEKG---ESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPG 1166 Query: 1696 VANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDA 1755 G +D +G +G E G +G + G A Sbjct: 1167 DPGPPGEGGPRGQDGAKG------DRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPG 1220 Query: 1756 AQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIAT 1815 ++G +G V G A + PD RG+ V QG Sbjct: 1221 SEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPG------PDGLRGLPGSVGQQGRPG 1274 Query: 1816 EDVADGIP---NEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVE 1872 G P G+ + A G + G+ QG + + G Sbjct: 1275 ATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPG------ 1328 Query: 1873 VQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQG 1929 QG + GI G G A A+ +G E VQG Sbjct: 1329 PQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKG---EKGVQG 1382 Score = 88.6 bits (218), Expect = 7e-17 Identities = 172/896 (19%), Positives = 247/896 (27%), Gaps = 79/896 (8%) Query: 654 VVANEDAAQAIAK--------PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVA 705 V A E AQAI + P G G +G + + QG Sbjct: 360 VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQG 419 Query: 706 AHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVAN 765 G + +G A D A+G+ + V+G D + G+ E G + G Sbjct: 420 LTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 479 Query: 766 EDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQG 825 ED +G E+ +G+ E +G+ GI GV D QG QG Sbjct: 480 EDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIP---GPPGVRGMDGPQGPKGSLGPQG 536 Query: 826 VANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPD 885 G G + HG E QG + L G+ ++ K Sbjct: 537 EPGPPGQQGTPGTQGLPGPQGAIGPHG---EKGPQG---KPGLPGMPGSDGPPGHPGKEG 590 Query: 886 AAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAA 945 N+G + G G+ Sbjct: 591 PPGTKGNQGPSGPQGPLGYPGPRGVKGV-------------------------------- 618 Query: 946 QGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHK 1005 G+ G ED G ++ +G E V G ED +G G Sbjct: 619 DGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGP 678 Query: 1006 DAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGI 1065 + G + G+ G +G G + E A G+S + +G Sbjct: 679 PGLMGEKGKLGVPGLP------GYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG- 731 Query: 1066 ANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAV 1125 E G + +G + +G + D HG E +G+ Sbjct: 732 --ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGE------------RGLPGPQGP 777 Query: 1126 QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHE 1185 G G +D + G + G + G QG A E G Sbjct: 778 NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 837 Query: 1186 DAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGI 1245 G E + G A + G A P RG E G A G Sbjct: 838 PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 897 Query: 1246 ANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPV 1305 G A G + G QG +G+ E G D V Sbjct: 898 EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGV 957 Query: 1306 QG-VANEDPI--QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDI 1362 QG V P GVA E +G + +G HG G + A Sbjct: 958 QGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGA 1017 Query: 1363 ANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAV 1422 E A+G +G G +QG+ +G +V G Sbjct: 1018 DGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGP 1077 Query: 1423 QGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE 1482 +G A + A G G +G E + GI E V+G E G + + Sbjct: 1078 RGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQ 1137 Query: 1483 ------VAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHG 1532 G +D P G G +D A G ED G Sbjct: 1138 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG 1193 Score = 87.4 bits (215), Expect = 1e-16 Identities = 177/965 (18%), Positives = 263/965 (27%), Gaps = 65/965 (6%) Query: 1306 QGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANE 1365 +G A D +G+ + V+G D + G+ E G G ED + E Sbjct: 430 RGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGE 489 Query: 1366 DAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGI 1425 +G+ E +G+ GI V+G+ D QG + QG QG Sbjct: 490 IGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGM---DGPQGPKGSLGPQGEPGPPGQQGT 546 Query: 1426 ANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAA 1485 G + HG G+ + G +G G + Sbjct: 547 PGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPS---GP 603 Query: 1486 HGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANE 1545 G + D RG+ +G ED G ++ +G E Sbjct: 604 QGPLGYPGPRGVKGVDGIRGLKGHKGEKG------------EDGFPGFKGDIGVKGDRGE 651 Query: 1546 VAVHGVAIEDAVQGVVKEVTAHGVANEDAV---QGVVNEDALHSVVANEDAAQAIAKPDA 1602 V V G ED +G G + +G + L + ++ P Sbjct: 652 VGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGF 711 Query: 1603 AHGIANEVAAHSIANKDAAQGIAN------QDAAQGIANEVAAHGISKEDAVQGIANEDA 1656 G + E A ++ K +G Q +G + A G S D G E Sbjct: 712 P-GASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGE-- 768 Query: 1657 AQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVAN 1716 +G+ G G +D + G G E QG GV Sbjct: 769 -RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHP------GQRGEVGFQGKTGPPGPPGV-- 819 Query: 1717 EVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHS 1776 V QG A E G G E G A ++ +G G + Sbjct: 820 -VGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRG 878 Query: 1777 VAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVA 1836 E G A P G A +G A G P G Sbjct: 879 FPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAG 938 Query: 1837 AHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIAN 1896 G+ E G D QG P+ G+ GVA ED +G + G Sbjct: 939 EKGVPGEKGPIGPTGRDGVQG-----PV-GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKG 992 Query: 1897 EDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQG 1956 G + A G E +G A+G ++ +G G Sbjct: 993 NKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKG---DEGTRGF------NG 1043 Query: 1957 IANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDA 2016 + G+ +G + G +G A + G P Sbjct: 1044 PPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPG 1103 Query: 2017 ARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVA 2076 +G E + GI E G E G + + P G ++G Sbjct: 1104 EKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTG--DDGPKGNPGP 1161 Query: 2077 DGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEV 2136 G D G E + QD A G ED G G G Sbjct: 1162 VGFPGDP--GPPGEGGPRG---QDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPA 1216 Query: 2137 AAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVA 2196 + G +G + A G + G A G + G + G Sbjct: 1217 GSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGAT 1276 Query: 2197 NEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQ 2256 + G G+ + A+G E G+ + G E R + + Sbjct: 1277 GQAGPPGPVGPPGLPGLRGDAGAKG---EKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSP 1333 Query: 2257 GIANE 2261 G E Sbjct: 1334 GQKGE 1338 Score = 85.5 bits (210), Expect = 6e-16 Identities = 215/1201 (17%), Positives = 326/1201 (27%), Gaps = 76/1201 (6%) Query: 16 SSEESLVHKDRGDGERPVNVRVVQVAPLRHESTPYEDT--VHDIANED--ADAAHGITNE 71 S E+ + + G ERP N + P R + +P + +H N++ + AAHG Sbjct: 220 SCEQKELECEGGQRERPQNQQ-----PHRAQRSPQQQPSRLHRPQNQEPQSQAAHG---- 270 Query: 72 DAVQGVANEVAAQGVANEDA-AHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQG 130 +G+ E V G G+ QG V G G Sbjct: 271 --PRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAG 328 Query: 131 VANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDA 190 + D G + G D +A ++A + A + Sbjct: 329 LPGSDGAPGPPGTSLMLPFR-----FGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPG 383 Query: 191 AQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAH 250 G + G +G + + QG + G + +G A +G+ Sbjct: 384 PMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPG 443 Query: 251 EDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHG 310 + V+G D G+ E G G ED +G E +G+ E G Sbjct: 444 DPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRG 503 Query: 311 VAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKEVT 370 + G+ + D G + QG G G + Sbjct: 504 LLGPKGPPGIPGPPGVRGM---DGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIG 560 Query: 371 AHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIA 430 HG E QG + L G+ ++ P G G QG Sbjct: 561 PHG---EKGPQG---KPGLPGMPGSDG-------PPGHPGKEGPPGTKGNQGPSGPQGPL 607 Query: 431 NEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAH 490 G+ D ++G+ +G ED G + V+G E V G E Sbjct: 608 GYPGPRGVKGVDGIRGLKGHKGEKG---EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPE 664 Query: 491 GVANKDAAHAIAKPDAARGIANEVAAQGI---ATEDVADGIANEDAVHGVANEVAAHGVA 547 G + P G ++ G+ G G + E A G++ Sbjct: 665 GPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLS 724 Query: 548 NEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQ 607 + P G + +G + A G + D HG E + G + Sbjct: 725 GKSGPRGERGPTGPRG---QRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 781 Query: 608 GVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKP 667 G G G EV G GVV A E Sbjct: 782 GPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQG----AAGETGPMGERGH 837 Query: 668 DAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGI 727 G E G A ++ +G A G G E + G A +G Sbjct: 838 PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 897 Query: 728 AHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAV 787 G A G A G QG +GV E G D V Sbjct: 898 EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGV 957 Query: 788 QGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKE 847 QG G+ GVA ED +G + +G HG G + Sbjct: 958 QGPV------GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQ 1011 Query: 848 VTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATE 907 A G E +G H ++ + P G+ +G+ +G T Sbjct: 1012 PGAAGADGEPGARGPQG----HFGAKGDEGTRGFNGPPGPIGL--QGLPGPSGEKG-ETG 1064 Query: 908 DVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVA 967 DV G + A + A G G E + G+ Sbjct: 1065 DV-------GPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQ 1117 Query: 968 NEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAH 1027 E +G E G E G +G D +G G Sbjct: 1118 GEPGVKGPRGE---RGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEG 1174 Query: 1028 GIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHED 1087 G +D A+G ED G G + G + G +G + Sbjct: 1175 GPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDP 1234 Query: 1088 AVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIA 1147 G + G A G + G + G + G + G+ Sbjct: 1235 GAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLR 1294 Query: 1148 NEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAH 1207 + A G G+ QG E +G+ G E + G + + Sbjct: 1295 GDAGAKGEKGHPGLIGLIGPPGEQG---EKGDRGLPGPQGSPGQKGEMGIPGASGPIGPG 1351 Query: 1208 G 1208 G Sbjct: 1352 G 1352 Score = 85.5 bits (210), Expect = 6e-16 Identities = 192/1049 (18%), Positives = 293/1049 (27%), Gaps = 76/1049 (7%) Query: 67 GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126 G T G +G + + G G + +G A A+G+ + Sbjct: 386 GYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDP 445 Query: 127 AVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIA 186 V+G D + G+ E +G G ED +G E + + E + + Sbjct: 446 GVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLL 505 Query: 187 NEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQ 246 GI V+G+ +G G + G QG + Sbjct: 506 GPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEK 565 Query: 247 GVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 306 G + + G+ D G + G G QG +G+ D Sbjct: 566 GPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSG------PQGPLGYPGPRGVKGVD 619 Query: 307 AVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVA 366 + G+ G ED G EV G ED +G G Sbjct: 620 GIRGLK---GHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTG-- 674 Query: 367 KEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAA 426 + G+ E GV L G + ++ P G + E A G++ + Sbjct: 675 -DPGPPGLMGEKGKLGV---PGLPGYPGRQGPKGSLGFP-GFPGASGEKGARGLSGKSGP 729 Query: 427 QGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKE 486 +G G + +G + A+G + D G E +G+ +G Sbjct: 730 RGERGPTGPRG---QRGPRGATGKSGAKGTSGGDGPHGPPGE---RGLPGPQGPNGFPGP 783 Query: 487 VAAHGVANKDA--AHAIAKPDAA-------RGIANEVAAQGIATEDVADGIANEDAVHGV 537 G KD H + + G V QG A E G G Sbjct: 784 KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGP 843 Query: 538 ANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAV 597 E G A ++ P A G +G E G A G Sbjct: 844 PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP 903 Query: 598 HGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVAN 657 G A +G A G QG GV E G D + G V Sbjct: 904 PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPV-- 961 Query: 658 EDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQG 717 G+ G+A ED +G + +G HG G Sbjct: 962 --------------GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIG 1007 Query: 718 IANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVE 777 + A G E +G G +G +QG+ +G +V Sbjct: 1008 PVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVG 1067 Query: 778 VQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVAN 837 G +G A + A G G +G E + G+ E V G Sbjct: 1068 PMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRG 1127 Query: 838 EDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVAN 897 E +G + G E G G N + P G Sbjct: 1128 ERGEKGES------GQPGEPGPPGPKGPTGDDGPKGNPG---PVGFPGDPGPPGEGGPRG 1178 Query: 898 EVAAQGIATEDVADGIAKDAAHGITKEEAAQA-IAKQDAAHSITNE--DAAQGVANEDAA 954 + A+G ED G + + G T E + K+ A S +E +G + A Sbjct: 1179 QDGAKGDRGEDGEPG--QPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGA 1236 Query: 955 HGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANE 1014 G + G A G + G + G + G + G+ + Sbjct: 1237 IGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGD 1296 Query: 1015 DAAH------GIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGIS------KEDAV 1062 A G+ + G E +G+ + G E+ G S + Sbjct: 1297 AGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGL 1356 Query: 1063 QGIANEDAAQGIANEDAAQGIAHEDAVQG 1091 G A A+G +G E VQG Sbjct: 1357 PGPAGPKGAKGATGPGGPKG---EKGVQG 1382 Score = 75.5 bits (184), Expect = 6e-13 Identities = 153/878 (17%), Positives = 231/878 (26%), Gaps = 40/878 (4%) Query: 1413 VQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQ---- 1468 V+G + G+ G V G G+ D A G + Sbjct: 290 VEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRF 349 Query: 1469 GIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANED 1528 G D VA + A + A A+ P G G G + + Sbjct: 350 GSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDL 409 Query: 1529 AAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVV 1588 G G + G A D +G+ + G D + G+ E Sbjct: 410 GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRG-- 467 Query: 1589 ANEDAAQAIAKP---DAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKE 1645 + AQ + P D G E+ + + +G+ GI G+ Sbjct: 468 --DTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGP 525 Query: 1646 DAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGV 1705 +G G + G QG G + G+ D G Sbjct: 526 QGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGH 585 Query: 1706 ANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAV 1765 ++ G G G GI G ED G + V Sbjct: 586 PGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGV 645 Query: 1766 QGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNE 1825 +G E V E G P G ++ G+ G P Sbjct: 646 KGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLP------GYPGR 699 Query: 1826 DAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGI 1885 G G S E +G++ + +G E G + +G + +G Sbjct: 700 QGPKGSLGFPGFPGASGEKGARGLSGKSGPRG---ERGPTGPRGQRGPRGATGKSGAKGT 756 Query: 1886 ANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAV 1945 + D HG E +G+ G +D + G Q G + Sbjct: 757 SGGDGPHGPPGE---RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGP 813 Query: 1946 QGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANE 2005 G QG A E G G E G A ++ +G + G + Sbjct: 814 PGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKG---DPGPPGAPGK 870 Query: 2006 DAAHAIAKPDAARGIANEVAAQGIATEDVADG------IANEDAAHGVANEDAAQAIAKP 2059 D + RG+ G+ + G E A G P Sbjct: 871 DGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGP 930 Query: 2060 DAAHGIANE-GIATEDVADG-IAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNE 2117 G A E G+ E G D VQG + G+ ED +G + Sbjct: 931 QGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVG------LPGPAGPPGVAGEDGDKGEVGD 984 Query: 2118 VAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGI 2177 +G HG G + A G E A+G +G G Sbjct: 985 PGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGP 1044 Query: 2178 AHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAV 2237 +QG+ +G +V G +G A A G G Sbjct: 1045 PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGE 1104 Query: 2238 HGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVHG 2275 G E + + E +G E G + + G Sbjct: 1105 KGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPG 1142 Score = 75.5 bits (184), Expect = 6e-13 Identities = 165/933 (17%), Positives = 241/933 (25%), Gaps = 98/933 (10%) Query: 1343 GIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANED 1402 G D +A ++A + A + G G ++G + + Sbjct: 350 GSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDL 409 Query: 1403 AVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIA 1462 QG + G + +G A D A G+ + G D G+ E +G Sbjct: 410 GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDT 469 Query: 1463 HEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHA---------IAKPDAARGIANEVATQ 1513 + G ED G E+ G+ E I P RG+ + Sbjct: 470 GAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPK 529 Query: 1514 GIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANED 1573 G + G E G QG+ G E QG + G+ D Sbjct: 530 G------SLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQG---KPGLPGMPGSD 580 Query: 1574 AVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGI 1633 G ++ N+ P G + D +G+ +G Sbjct: 581 GPPGHPGKEGPPGTKGNQG-------PSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG- 632 Query: 1634 ANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAA 1693 ED G + +G E V G ED G Sbjct: 633 --------------------EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGP 672 Query: 1694 HGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANE 1753 G + G + V G + G +G G + E A G++ + Sbjct: 673 TGDPGPPGLMGEKGKLGVPG------LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGK 726 Query: 1754 DAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGI 1813 +G E G + + A G + D H P RG+ G Sbjct: 727 SGPRG---ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHG---PPGERGLPGPQGPNGF 780 Query: 1814 ATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEV 1873 G P +D G G E QG G+ QG A E Sbjct: 781 PGPKGPPGPPGKDGLPG------HPGQRGEVGFQGKTGPPGPPGVVGP---QGAAGETGP 831 Query: 1874 QGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQ 1933 G G E G A ++ +G A +G E + G A Sbjct: 832 MGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGG 891 Query: 1934 DAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGI 1993 +G G A +G A G QG +G+ E G Sbjct: 892 PGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP 951 Query: 1994 ANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAA 2053 D V G G+ G+A ED G + G Sbjct: 952 TGRDGVQGPV---------------GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGE 996 Query: 2054 QAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQG 2113 P G + + G E A+ A G G Sbjct: 997 HGPPGPPGPIG-------------PVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNG 1043 Query: 2114 VTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVE 2173 + QG+ G +V G +G A A G G Sbjct: 1044 PPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPG 1103 Query: 2174 VQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVAN 2233 +G + GI E +G E G E G +G +D +G Sbjct: 1104 EKGEPGESGSPGIQGEPGVKGPRGE---RGEKGESGQPGEPGPPGPKGPTGDDGPKGNPG 1160 Query: 2234 EVAVHGVANEDAARHMAKEDAAQGIANEDAAHG 2266 V G +D A+G ED G Sbjct: 1161 PVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG 1193 Score = 56.6 bits (135), Expect = 3e-07 Identities = 85/483 (17%), Positives = 132/483 (27%), Gaps = 13/483 (2%) Query: 1798 PDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQG 1857 P G + +G A D A G+P + G G+ E +G G Sbjct: 417 PQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPG 476 Query: 1858 IAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAN--- 1914 ED +G E+ +G+ E +G+ GI +G+ + Sbjct: 477 PPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQG 536 Query: 1915 EDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQG 1974 E G QG+ A G E QG G G +G Sbjct: 537 EPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKG 596 Query: 1975 IANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDV 2034 QG +G+ D + G+ D G ++ +G E Sbjct: 597 NQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG---EDGFPGFKGDIGVKGDRGEVG 653 Query: 2035 ADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQ 2094 G ED G P G + + + +G Sbjct: 654 VPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK-LGVPGLPGYPGRQGPKGSLGFPGFP 712 Query: 2095 AIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEV 2154 + + A G++ + +G E G + G + A G + D G E Sbjct: 713 GASGEKGARGLSGKSGPRG---ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGE- 768 Query: 2155 AAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVA 2214 +G+ G G KD + G + G + G QG A Sbjct: 769 --RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAA 826 Query: 2215 NEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVH 2274 E G G E + G A ++ + A G G E + Sbjct: 827 GETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLP 886 Query: 2275 GIA 2277 G A Sbjct: 887 GTA 889 Score = 37.7 bits (86), Expect = 0.14 Identities = 73/380 (19%), Positives = 103/380 (27%), Gaps = 34/380 (8%) Query: 1927 VQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQ---- 1982 V+G + G+ +QG G G+ D A G Sbjct: 290 VEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRF 349 Query: 1983 GIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANED 2042 G D +A ++A + A A+ P G G + + G+ E Sbjct: 350 GSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLG---QPGSPGLKGES 406 Query: 2043 AAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAED----------AVQGITNEEA 2092 G Q + P G G A D A G+ D + G+ E+ Sbjct: 407 GDLGPQGPRGPQGLTGPPGKAG--RRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKG 464 Query: 2093 AQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANE------DA 2146 + G ED +G E+ +G+ E G+ G+ D Sbjct: 465 HRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDG 524 Query: 2147 AQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVAN 2206 QG + QG QG QG+ G E QG G Sbjct: 525 PQGPKGSLGPQGEPGPPGQQGTPG---TQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG 581 Query: 2207 EDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAK------EDAAQGIAN 2260 G +G QG GV D R + ED G Sbjct: 582 PPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKG 641 Query: 2261 EDAAHGIANEDAVHGIANED 2280 + G E V G ED Sbjct: 642 DIGVKGDRGEVGVPGSRGED 661 >gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo sapiens] Length = 1736 Score = 98.6 bits (244), Expect = 6e-20 Identities = 174/919 (18%), Positives = 253/919 (27%), Gaps = 55/919 (5%) Query: 1116 VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIAN 1175 ++G + + QG + G + +G A D A G+ + G D G+ Sbjct: 509 LKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPG 568 Query: 1176 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQG 1235 E +G + G ED G E+ G+ E + P GI +G Sbjct: 569 EKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRG 628 Query: 1236 IATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDA 1295 + G G + G QG +G + + G+ D Sbjct: 629 MDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG 688 Query: 1296 AQG-IAKEDPVQGVANEDPI--QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQG 1352 G KE P N+ P QG +GV D ++G+ +G Sbjct: 689 PPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGH------------KG 736 Query: 1353 IANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVE 1412 ED + +G E V G ED +G G + G ++ Sbjct: 737 EKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLG 796 Query: 1413 VQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIAN 1472 V G + G G G + E A+G++ + +G E G Sbjct: 797 VPG------LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG---ERGPTGPRG 847 Query: 1473 EDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHG 1532 + G + A G + D H P RG+ G G +D G Sbjct: 848 QRGPRGATGKSGAKGTSGGDGPHG---PPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPG 904 Query: 1533 VANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANED 1592 + G + G QG E G G E L A ++ Sbjct: 905 HPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPG-TAGKE 963 Query: 1593 AAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQ--- 1649 + P A G KD G+ +G+ G+ + Sbjct: 964 GTKGDPGPPGAPG------------KDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPP 1011 Query: 1650 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANED 1709 G A +G A G QG GV E G D VQG Sbjct: 1012 GPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPV--- 1068 Query: 1710 AVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIA 1769 G+ GVA ED +G + G HG G + G Sbjct: 1069 ---GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGAD 1125 Query: 1770 NEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAH 1829 E A G + P +G+ +G + G P Sbjct: 1126 GEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPR 1185 Query: 1830 GVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANED 1889 G A A G G +G E G+ E V+G E +G E Sbjct: 1186 GPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGE---RGEKGES 1242 Query: 1890 AAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIA 1949 G +G +D + G G QD A+G ED G Sbjct: 1243 GQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG-- 1300 Query: 1950 NEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAH 2009 + + G E G + G + QG G G Sbjct: 1301 -QPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPA 1359 Query: 2010 AIAKPDAARGIANEVAAQG 2028 PD RG+ V QG Sbjct: 1360 GKPGPDGLRGLPGSVGQQG 1378 Score = 94.7 bits (234), Expect = 9e-19 Identities = 191/1067 (17%), Positives = 289/1067 (27%), Gaps = 62/1067 (5%) Query: 923 KEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVH 982 +E AQAI +Q A ++ G G +G + ++ QG + Sbjct: 470 QEAQAQAILQQ-ARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLT 528 Query: 983 GVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANED 1042 G + +G A +G+ ++G D G+ E G G ED Sbjct: 529 GPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED 588 Query: 1043 AAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVA 1102 +G E+ G+ E +G+ GI +G+ +G G Sbjct: 589 GERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPP 648 Query: 1103 KEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAA- 1161 + G QG +G + + G+ D G ++ G Sbjct: 649 GQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPS 708 Query: 1162 -----------HGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVA 1210 G+ D +G+ +G ED G + V G EV G Sbjct: 709 GPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG---EDGFPGFKGDIGVKGDRGEVGVPGSR 765 Query: 1211 NEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQ 1270 ED P+ +G G G+ E GV + Sbjct: 766 GEDG------PEGPKGRTGPTGDPG------PPGLMGEKGKLGV------------PGLP 801 Query: 1271 GIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHED 1330 G +G G + E A+G++ + G E G + +G + Sbjct: 802 GYPGRQGPKGSLGFPGFPGASGEKGARGLSGK---SGPRGERGPTGPRGQRGPRGATGKS 858 Query: 1331 AVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIA 1390 +G + D HG E +G+ G +D + G + G Sbjct: 859 GAKGTSGGDGPHGPPGE---RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQ 915 Query: 1391 KEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQ 1450 + G QG A E G G E G A + G A Sbjct: 916 GKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAP 975 Query: 1451 GIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEV 1510 G +G E + G A + G G A A G Sbjct: 976 GKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP 1035 Query: 1511 ATQGIATEDVADGIANEDAAHGVANEVAAQ---GIANEVAVHGVAIEDAVQGVVKEVTAH 1567 QG G+ E G Q G+ GVA ED +G V + Sbjct: 1036 GPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQK 1095 Query: 1568 GVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQ 1627 G G V AA A +P A G A G Sbjct: 1096 GTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEP-GARGPQGHFGAKGDEGTRGFNGPPGP 1154 Query: 1628 DAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1687 QG+ G + + G +G A + A G G G Sbjct: 1155 IGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGE 1214 Query: 1688 AKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAA 1747 E + G+ E V+G E +G + + G +G +D G V Sbjct: 1215 PGESGSPGIQGEPGVKGPRGERGEKGESGQ---PGEPGPPGPKGPTGDDGPKGNPGPVGF 1271 Query: 1748 HGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANE 1807 G G +D +G ED E G + P RG A Sbjct: 1272 PGDPGPPGEGGPRGQDGAKGDRGEDG------EPGQPGSPGPTGENGPPGPLGKRGPAGS 1325 Query: 1808 VAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGV 1867 ++G A G P A G V G + + G+ + G + G Sbjct: 1326 PGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVG---QQGRPGA 1382 Query: 1868 ANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAV 1927 + G + G+ + A G G+ Q + G Sbjct: 1383 TGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQ 1442 Query: 1928 QGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQG 1974 +G A G G+ +G G E QG Sbjct: 1443 KGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQG 1489 Score = 94.7 bits (234), Expect = 9e-19 Identities = 173/939 (18%), Positives = 255/939 (27%), Gaps = 28/939 (2%) Query: 62 ADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQG 121 AD A G+ + V+G G+ E G G ED +G E+ +G Sbjct: 542 ADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRG 601 Query: 122 VANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDA 181 + E +G+ G+ V+G+ G G + Sbjct: 602 LPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPG 661 Query: 182 AQDIANEDAAQGISKEDAVQGIANEDAAQG-IAKEDPVQGVANEDP--VQGVANEDAVQG 238 Q +G + + G+ D G KE P N+ P QG +G Sbjct: 662 PQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRG 721 Query: 239 VANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDA 298 V V G+ +G ED G ++ G E G ED +G Sbjct: 722 VKG---VDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTG 778 Query: 299 VQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIAN 358 G + G ++ G+ G +G G Sbjct: 779 PTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG 838 Query: 359 EDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAH 418 E G + G + +G D HG + + P +G Sbjct: 839 ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHG----PPGERGLPGPQGPNGFPGPKGPP 894 Query: 419 GIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANED 478 G +D G + G + G QG A E G G E Sbjct: 895 GPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQ 954 Query: 479 AVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVA 538 + G A + G A P RG E G A G G A Sbjct: 955 GLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPA 1014 Query: 539 NEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVH 598 G A G +G+ E G D GV V + Sbjct: 1015 GSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRD---GVQGPVGLP 1071 Query: 599 GVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANE 658 G A GVA ED G + +G HG G V + G E Sbjct: 1072 GPA---GPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAG-ADGE 1127 Query: 659 DAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGI 718 A+ A G +G QG+ +G +V G +G Sbjct: 1128 PGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGP 1187 Query: 719 ANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEV 778 A + A G G G E + G+ E V+G E +G E Sbjct: 1188 AGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGE---RGEKGESGQ 1244 Query: 779 QGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANE 838 G +G +D G V G G +D A+G ED G + Sbjct: 1245 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGED---GEPGQ 1301 Query: 839 DAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANE 898 + G E G + G E G + AI P + G A + Sbjct: 1302 PGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK 1361 Query: 899 VAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVA 958 G+ + + + G T + + + A+G G+ Sbjct: 1362 PGPDGL--RGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLI 1419 Query: 959 NEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEV 997 QG E +G+ G E + G + + Sbjct: 1420 GPPGEQG---EKGDRGLPGPQGSPGQKGEMGIPGASGPI 1455 Score = 90.9 bits (224), Expect = 1e-17 Identities = 195/1042 (18%), Positives = 294/1042 (28%), Gaps = 72/1042 (6%) Query: 392 VVANEDAAQAIAK--------PDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDA 443 V A E AQAI + P G G +G + ++ G Sbjct: 467 VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQG 526 Query: 444 VQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAK 503 + G + +G A D A+G+ + V+G D + G+ E G Sbjct: 527 LTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 586 Query: 504 PDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHG 563 D RG E+ +G+ E G+ G+ G+ P G Sbjct: 587 EDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPG 646 Query: 564 IANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANE-- 621 + T G G G + + G+ D G ++ G Sbjct: 647 PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQG 706 Query: 622 -DAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAH 680 QG GV D ++G+ G ED G EV Sbjct: 707 PSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG----EDGFPGFKGDIGVKGDRGEVGVP 762 Query: 681 GIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANED 740 G ED +G G G + V G+ QG +G Sbjct: 763 GSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQG------PKGSLGFP 816 Query: 741 AVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIA 800 G + E A G++ + G E G + +G + +G + D HG Sbjct: 817 GFPGASGEKGARGLSGK---SGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPP 873 Query: 801 NEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQ 860 E G+ G G +D + G G EV G T Sbjct: 874 GE---RGLPGPQGPNGFPGPKGPPGPPGKDGLPG------HPGQRGEVGFQGKTGPPGPP 924 Query: 861 GVVNEEALHGVVA--NEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAA 918 GVV + G E P G+ G A + +G A G KD Sbjct: 925 GVVGPQGAAGETGPMGERGHPGPPGPPGEQGL--PGTAGKEGTKGDPGPPGAPG--KDGP 980 Query: 919 HGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANE 978 G+ + + + + G + G E A G + G Sbjct: 981 AGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPG---ERGAAGSGGPIGPPGRPGP 1037 Query: 979 DAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGI 1038 G A E V G + G +D +QG G+ G+A ED +G Sbjct: 1038 QGPPGAAGEKGVPGEKGPI---GPTGRDGVQGPV------GLPGPAGPPGVAGEDGDKGE 1088 Query: 1039 ANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAV 1098 + +G HG G + A G E A+G +G ++ Sbjct: 1089 VGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKG---DEGT 1145 Query: 1099 HGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANE 1158 G +G +QG+ +G +V G +G A + A G Sbjct: 1146 RGF------NGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGP 1199 Query: 1159 VAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAI 1218 G +G E + GI E V+G E G E G Sbjct: 1200 PGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGE---RGEKGESGQPGEPGPPGPKGP 1256 Query: 1219 AKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAA 1278 D +G V G G +D A G E G + G E+ Sbjct: 1257 TGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG---QPGSPGPTGENGP 1313 Query: 1279 QGIAKEDAVQGIANEDAAQG--IAKEDP-VQGVANEDPIQGVANEVEVQGVAHEDAVQGI 1335 G + G + QG AK DP G + G A G + G Sbjct: 1314 PGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGS 1373 Query: 1336 ANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPV 1395 + G + G + + A+G + G+ QG E Sbjct: 1374 VGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQG---EKGD 1430 Query: 1396 QGVANEDAVQGVANEVEVQGVA 1417 +G+ G E+ + G + Sbjct: 1431 RGLPGPQGSPGQKGEMGIPGAS 1452 Score = 90.5 bits (223), Expect = 2e-17 Identities = 190/1017 (18%), Positives = 273/1017 (26%), Gaps = 73/1017 (7%) Query: 916 DAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGV 975 D A G+ + + D + E +G G ED +G E+ +G+ Sbjct: 543 DGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGL 602 Query: 976 ANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAA 1035 E G+ G+ V+G+ +G G + G Sbjct: 603 PGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGP 662 Query: 1036 QGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANE 1095 QG +G + G+ D G ++ G G G Sbjct: 663 QGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGV 722 Query: 1096 DAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGI 1155 V G+ G ED G + V+G EV V G ED +G G Sbjct: 723 KGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEG---PKGRTGP 779 Query: 1156 ANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAA 1215 + G+ E G+ G +G G + E A G++ + Sbjct: 780 TGDPGPPGLMGEKGKLGV---PGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGP 836 Query: 1216 HAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANE 1275 P RG + +G + A G + D HG E G+ G Sbjct: 837 RGERGPTGPRG---QRGPRGATGKSGAKGTSGGDGPHGPPGE---RGLPGPQGPNGFPGP 890 Query: 1276 DAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGI 1335 G +D + G + G + G QG A E G G Sbjct: 891 KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGP 950 Query: 1336 ANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPV 1395 E G A ++ +G A +G E + G A +G Sbjct: 951 PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP 1010 Query: 1396 QGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANE 1455 G A +G A G QG G+ E G D QG Sbjct: 1011 PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQG---- 1066 Query: 1456 DAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGI 1515 G+ G+A ED G + G H P G + G Sbjct: 1067 --PVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAG- 1123 Query: 1516 ATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAV 1575 ADG E A G A+G +G +QG+ G + E Sbjct: 1124 -----ADG---EPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGL------PGPSGEKGE 1169 Query: 1576 QGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIAN 1635 G V P G A A G +G Sbjct: 1170 TGDV-------------GPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG 1216 Query: 1636 EVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHG 1695 E + GI E V+G E +G E G +G +D G V G Sbjct: 1217 ESGSPGIQGEPGVKGPRGERGEKG---ESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPG 1273 Query: 1696 VANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDA 1755 G +D +G +G E G +G + G A Sbjct: 1274 DPGPPGEGGPRGQDGAKG------DRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPG 1327 Query: 1756 AQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIAT 1815 ++G +G V G A + PD RG+ V QG Sbjct: 1328 SEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPG------PDGLRGLPGSVGQQGRPG 1381 Query: 1816 EDVADGIP---NEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVE 1872 G P G+ + A G + G+ QG + + G Sbjct: 1382 ATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPG------ 1435 Query: 1873 VQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQG 1929 QG + GI G G A A+ +G E VQG Sbjct: 1436 PQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKG---EKGVQG 1489 Score = 88.6 bits (218), Expect = 7e-17 Identities = 172/896 (19%), Positives = 247/896 (27%), Gaps = 79/896 (8%) Query: 654 VVANEDAAQAIAK--------PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVA 705 V A E AQAI + P G G +G + + QG Sbjct: 467 VAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQG 526 Query: 706 AHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVAN 765 G + +G A D A+G+ + V+G D + G+ E G + G Sbjct: 527 LTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPG 586 Query: 766 EDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQG 825 ED +G E+ +G+ E +G+ GI GV D QG QG Sbjct: 587 EDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIP---GPPGVRGMDGPQGPKGSLGPQG 643 Query: 826 VANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPD 885 G G + HG E QG + L G+ ++ K Sbjct: 644 EPGPPGQQGTPGTQGLPGPQGAIGPHG---EKGPQG---KPGLPGMPGSDGPPGHPGKEG 697 Query: 886 AAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAA 945 N+G + G G+ Sbjct: 698 PPGTKGNQGPSGPQGPLGYPGPRGVKGV-------------------------------- 725 Query: 946 QGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHK 1005 G+ G ED G ++ +G E V G ED +G G Sbjct: 726 DGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGP 785 Query: 1006 DAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGI 1065 + G + G+ G +G G + E A G+S + +G Sbjct: 786 PGLMGEKGKLGVPGLP------GYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRG- 838 Query: 1066 ANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAV 1125 E G + +G + +G + D HG E +G+ Sbjct: 839 --ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGE------------RGLPGPQGP 884 Query: 1126 QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHE 1185 G G +D + G + G + G QG A E G Sbjct: 885 NGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 944 Query: 1186 DAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGI 1245 G E + G A + G A P RG E G A G Sbjct: 945 PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGN 1004 Query: 1246 ANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPV 1305 G A G + G QG +G+ E G D V Sbjct: 1005 EGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGV 1064 Query: 1306 QG-VANEDPI--QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDI 1362 QG V P GVA E +G + +G HG G + A Sbjct: 1065 QGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGA 1124 Query: 1363 ANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAV 1422 E A+G +G G +QG+ +G +V G Sbjct: 1125 DGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGP 1184 Query: 1423 QGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE 1482 +G A + A G G +G E + GI E V+G E G + + Sbjct: 1185 RGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQ 1244 Query: 1483 ------VAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHG 1532 G +D P G G +D A G ED G Sbjct: 1245 PGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG 1300 Score = 87.4 bits (215), Expect = 1e-16 Identities = 177/965 (18%), Positives = 263/965 (27%), Gaps = 65/965 (6%) Query: 1306 QGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANE 1365 +G A D +G+ + V+G D + G+ E G G ED + E Sbjct: 537 RGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGE 596 Query: 1366 DAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGI 1425 +G+ E +G+ GI V+G+ D QG + QG QG Sbjct: 597 IGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGM---DGPQGPKGSLGPQGEPGPPGQQGT 653 Query: 1426 ANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAA 1485 G + HG G+ + G +G G + Sbjct: 654 PGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPS---GP 710 Query: 1486 HGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANE 1545 G + D RG+ +G ED G ++ +G E Sbjct: 711 QGPLGYPGPRGVKGVDGIRGLKGHKGEKG------------EDGFPGFKGDIGVKGDRGE 758 Query: 1546 VAVHGVAIEDAVQGVVKEVTAHGVANEDAV---QGVVNEDALHSVVANEDAAQAIAKPDA 1602 V V G ED +G G + +G + L + ++ P Sbjct: 759 VGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGF 818 Query: 1603 AHGIANEVAAHSIANKDAAQGIAN------QDAAQGIANEVAAHGISKEDAVQGIANEDA 1656 G + E A ++ K +G Q +G + A G S D G E Sbjct: 819 P-GASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGE-- 875 Query: 1657 AQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVAN 1716 +G+ G G +D + G G E QG GV Sbjct: 876 -RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHP------GQRGEVGFQGKTGPPGPPGV-- 926 Query: 1717 EVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHS 1776 V QG A E G G E G A ++ +G G + Sbjct: 927 -VGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRG 985 Query: 1777 VAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVA 1836 E G A P G A +G A G P G Sbjct: 986 FPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAG 1045 Query: 1837 AHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIAN 1896 G+ E G D QG P+ G+ GVA ED +G + G Sbjct: 1046 EKGVPGEKGPIGPTGRDGVQG-----PV-GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKG 1099 Query: 1897 EDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQG 1956 G + A G E +G A+G ++ +G G Sbjct: 1100 NKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKG---DEGTRGF------NG 1150 Query: 1957 IANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDA 2016 + G+ +G + G +G A + G P Sbjct: 1151 PPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPG 1210 Query: 2017 ARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVA 2076 +G E + GI E G E G + + P G ++G Sbjct: 1211 EKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTG--DDGPKGNPGP 1268 Query: 2077 DGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEV 2136 G D G E + QD A G ED G G G Sbjct: 1269 VGFPGDP--GPPGEGGPRG---QDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPA 1323 Query: 2137 AAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVA 2196 + G +G + A G + G A G + G + G Sbjct: 1324 GSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGAT 1383 Query: 2197 NEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQ 2256 + G G+ + A+G E G+ + G E R + + Sbjct: 1384 GQAGPPGPVGPPGLPGLRGDAGAKG---EKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSP 1440 Query: 2257 GIANE 2261 G E Sbjct: 1441 GQKGE 1445 Score = 85.5 bits (210), Expect = 6e-16 Identities = 192/1049 (18%), Positives = 293/1049 (27%), Gaps = 76/1049 (7%) Query: 67 GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126 G T G +G + + G G + +G A A+G+ + Sbjct: 493 GYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDP 552 Query: 127 AVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIA 186 V+G D + G+ E +G G ED +G E + + E + + Sbjct: 553 GVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLL 612 Query: 187 NEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQ 246 GI V+G+ +G G + G QG + Sbjct: 613 GPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEK 672 Query: 247 GVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 306 G + + G+ D G + G G QG +G+ D Sbjct: 673 GPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSG------PQGPLGYPGPRGVKGVD 726 Query: 307 AVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVA 366 + G+ G ED G EV G ED +G G Sbjct: 727 GIRGLK---GHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTG-- 781 Query: 367 KEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAA 426 + G+ E GV L G + ++ P G + E A G++ + Sbjct: 782 -DPGPPGLMGEKGKLGV---PGLPGYPGRQGPKGSLGFP-GFPGASGEKGARGLSGKSGP 836 Query: 427 QGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKE 486 +G G + +G + A+G + D G E +G+ +G Sbjct: 837 RGERGPTGPRG---QRGPRGATGKSGAKGTSGGDGPHGPPGE---RGLPGPQGPNGFPGP 890 Query: 487 VAAHGVANKDA--AHAIAKPDAA-------RGIANEVAAQGIATEDVADGIANEDAVHGV 537 G KD H + + G V QG A E G G Sbjct: 891 KGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGP 950 Query: 538 ANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAV 597 E G A ++ P A G +G E G A G Sbjct: 951 PGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGP 1010 Query: 598 HGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVAN 657 G A +G A G QG GV E G D + G V Sbjct: 1011 PGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPV-- 1068 Query: 658 EDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQG 717 G+ G+A ED +G + +G HG G Sbjct: 1069 --------------GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIG 1114 Query: 718 IANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVE 777 + A G E +G G +G +QG+ +G +V Sbjct: 1115 PVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVG 1174 Query: 778 VQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVAN 837 G +G A + A G G +G E + G+ E V G Sbjct: 1175 PMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRG 1234 Query: 838 EDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVAN 897 E +G + G E G G N + P G Sbjct: 1235 ERGEKGES------GQPGEPGPPGPKGPTGDDGPKGNPG---PVGFPGDPGPPGEGGPRG 1285 Query: 898 EVAAQGIATEDVADGIAKDAAHGITKEEAAQA-IAKQDAAHSITNE--DAAQGVANEDAA 954 + A+G ED G + + G T E + K+ A S +E +G + A Sbjct: 1286 QDGAKGDRGEDGEPG--QPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGA 1343 Query: 955 HGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANE 1014 G + G A G + G + G + G + G+ + Sbjct: 1344 IGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGD 1403 Query: 1015 DAAH------GIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGIS------KEDAV 1062 A G+ + G E +G+ + G E+ G S + Sbjct: 1404 AGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPPGL 1463 Query: 1063 QGIANEDAAQGIANEDAAQGIAHEDAVQG 1091 G A A+G +G E VQG Sbjct: 1464 PGPAGPKGAKGATGPGGPKG---EKGVQG 1489 Score = 82.0 bits (201), Expect = 6e-15 Identities = 207/1170 (17%), Positives = 313/1170 (26%), Gaps = 63/1170 (5%) Query: 49 PYEDTVH--DIANEDADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANE-VAAHGVA 105 PY+ T D E+ + ++ E A G A +G+ E V + G Sbjct: 343 PYDYTYGYGDDYREETELGPALSAETAHSGAAAH-GPRGLKGEKGEPAVLEPGMLVEGPP 401 Query: 106 NEDAAQGVANEVAAQGVANEDAVQGVANEDAVQGVANEDAVQGIANEDAA----HGIANE 161 + G+ QG G G+ D G G Sbjct: 402 GPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGG 461 Query: 162 DAAQGIANEDAAQDIAKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGV 221 D +A ++A + A + G + G +G + + QG Sbjct: 462 DKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGP 521 Query: 222 ANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAA 281 + G + +G A +G+ + V+G D G+ E G Sbjct: 522 RGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGL 581 Query: 282 QGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANE 341 G ED +G E +G+ E G+ G+ + D G Sbjct: 582 PGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGM---DGPQGPKGS 638 Query: 342 VATQGIATEDVADGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQA 401 + QG G G + HG E QG + L G+ ++ Sbjct: 639 LGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHG---EKGPQG---KPGLPGMPGSDG---- 688 Query: 402 IAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDA 461 P G G QG G+ D ++G+ +G ED Sbjct: 689 ---PPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG---EDG 742 Query: 462 AQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGI-- 519 G + V+G E V G E G + P G ++ G+ Sbjct: 743 FPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPG 802 Query: 520 -ATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDV 578 G G + E A G++ + P G + +G + Sbjct: 803 YPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGERGPTGPRG---QRGPRGATGKSG 859 Query: 579 ADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVAN 638 A G + D HG E + G + G G G EV G Sbjct: 860 AKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTG 919 Query: 639 EDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQ 698 GVV A E G E G A ++ +G A Sbjct: 920 PPGPPGVVGPQG----AAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAP 975 Query: 699 GIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANED 758 G G E + G A +G G A G A G Sbjct: 976 GKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP 1035 Query: 759 PVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVA 818 QG +GV E G D VQG G+ GVA ED +G Sbjct: 1036 GPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPV------GLPGPAGPPGVAGEDGDKGEV 1089 Query: 819 NEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAA 878 + +G HG G + A G E +G H ++ Sbjct: 1090 GDPGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQG----HFGAKGDEGT 1145 Query: 879 QAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHS 938 + P G+ +G+ +G T DV G + A + A Sbjct: 1146 RGFNGPPGPIGL--QGLPGPSGEKG-ETGDV-------GPMGPPGPPGPRGPAGPNGADG 1195 Query: 939 ITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVE 998 G G E + G+ E +G E G E G Sbjct: 1196 PQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGE---RGEKGESGQPGEPGPPG 1252 Query: 999 VQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISK 1058 +G D +G G G +D A+G ED G G + Sbjct: 1253 PKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENG 1312 Query: 1059 EDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQG 1118 G + G +G + G + G A G + G Sbjct: 1313 PPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPG 1372 Query: 1119 VANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDA 1178 + G + G + G+ + A G G+ QG E Sbjct: 1373 SVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQG---EKG 1429 Query: 1179 AQGIAHEDAVQGIANEDAVHGVAKEVAAHG 1208 +G+ G E + G + + G Sbjct: 1430 DRGLPGPQGSPGQKGEMGIPGASGPIGPGG 1459 Score = 77.8 bits (190), Expect = 1e-13 Identities = 162/913 (17%), Positives = 246/913 (26%), Gaps = 44/913 (4%) Query: 1380 IANEDAAQGIAKEDP--VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANE 1437 ++ E A G A P ++G E AV + + V+G + G+ G Sbjct: 364 LSAETAHSGAAAHGPRGLKGEKGEPAV--LEPGMLVEGPPGPEGPAGLIGPPGIQGNPGP 421 Query: 1438 VAAHGIANEDAAQGIANEDAAQGIAHEDAVQ----GIANEDAVHGVAKEVAAHGVANEDA 1493 V G G+ D A G + G D VA + A + A Sbjct: 422 VGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQA 481 Query: 1494 AHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAI 1553 A+ P G G G + + G G + G A Sbjct: 482 RLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAG 541 Query: 1554 EDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKP---DAAHGIANEV 1610 D +G+ + G D + G+ E + AQ + P D G E+ Sbjct: 542 ADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRG----DTGAQGLPGPPGEDGERGDDGEI 597 Query: 1611 AAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIA 1670 + + +G+ GI G+ +G G + G Sbjct: 598 GPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQ 657 Query: 1671 HEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQ 1730 QG G + G+ D G ++ G G Sbjct: 658 GLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYP 717 Query: 1731 GIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANED 1790 G GI G ED G + V+G E V E G Sbjct: 718 GPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRT 777 Query: 1791 AAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIA 1850 P G ++ G+ G P G G S E +G++ Sbjct: 778 GPTGDPGPPGLMGEKGKLGVPGLP------GYPGRQGPKGSLGFPGFPGASGEKGARGLS 831 Query: 1851 NEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQ 1910 + +G E G + +G + +G + D HG E +G+ Sbjct: 832 GKSGPRG---ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGE---RGLPGPQGPN 885 Query: 1911 DIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANED 1970 G +D + G Q G + G QG A E G Sbjct: 886 GFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHP 945 Query: 1971 AAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIA 2030 G E G A ++ +G + G +D + RG+ G+ Sbjct: 946 GPPGPPGEQGLPGTAGKEGTKG---DPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLK 1002 Query: 2031 TEDVADG------IANEDAAHGVANEDAAQAIAKPDAAHGIANE-GIATEDVADG-IAED 2082 + G E A G P G A E G+ E G D Sbjct: 1003 GNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRD 1062 Query: 2083 AVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVA 2142 VQG + G+ ED +G + +G HG G Sbjct: 1063 GVQGPVG------LPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPV 1116 Query: 2143 NEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAH 2202 + A G E A+G +G G +QG+ +G +V Sbjct: 1117 GQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPM 1176 Query: 2203 GVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANED 2262 G +G A A G G G E + + E +G E Sbjct: 1177 GPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGER 1236 Query: 2263 AAHGIANEDAVHG 2275 G + + G Sbjct: 1237 GEKGESGQPGEPG 1249 Score = 75.5 bits (184), Expect = 6e-13 Identities = 165/933 (17%), Positives = 241/933 (25%), Gaps = 98/933 (10%) Query: 1343 GIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANED 1402 G D +A ++A + A + G G ++G + + Sbjct: 457 GSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDL 516 Query: 1403 AVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIA 1462 QG + G + +G A D A G+ + G D G+ E +G Sbjct: 517 GPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDT 576 Query: 1463 HEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHA---------IAKPDAARGIANEVATQ 1513 + G ED G E+ G+ E I P RG+ + Sbjct: 577 GAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPK 636 Query: 1514 GIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANED 1573 G + G E G QG+ G E QG + G+ D Sbjct: 637 G------SLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQG---KPGLPGMPGSD 687 Query: 1574 AVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGI 1633 G ++ N+ P G + D +G+ +G Sbjct: 688 GPPGHPGKEGPPGTKGNQG-------PSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG- 739 Query: 1634 ANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAA 1693 ED G + +G E V G ED G Sbjct: 740 --------------------EDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGP 779 Query: 1694 HGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANE 1753 G + G + V G + G +G G + E A G++ + Sbjct: 780 TGDPGPPGLMGEKGKLGVPG------LPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGK 833 Query: 1754 DAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGI 1813 +G E G + + A G + D H P RG+ G Sbjct: 834 SGPRG---ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHG---PPGERGLPGPQGPNGF 887 Query: 1814 ATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEV 1873 G P +D G G E QG G+ QG A E Sbjct: 888 PGPKGPPGPPGKDGLPG------HPGQRGEVGFQGKTGPPGPPGVVGP---QGAAGETGP 938 Query: 1874 QGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQ 1933 G G E G A ++ +G A +G E + G A Sbjct: 939 MGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGG 998 Query: 1934 DAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGI 1993 +G G A +G A G QG +G+ E G Sbjct: 999 PGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP 1058 Query: 1994 ANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAA 2053 D V G G+ G+A ED G + G Sbjct: 1059 TGRDGVQGPV---------------GLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGE 1103 Query: 2054 QAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQG 2113 P G + + G E A+ A G G Sbjct: 1104 HGPPGPPGPIG-------------PVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNG 1150 Query: 2114 VTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVE 2173 + QG+ G +V G +G A A G G Sbjct: 1151 PPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPG 1210 Query: 2174 VQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVAN 2233 +G + GI E +G E G E G +G +D +G Sbjct: 1211 EKGEPGESGSPGIQGEPGVKGPRGE---RGEKGESGQPGEPGPPGPKGPTGDDGPKGNPG 1267 Query: 2234 EVAVHGVANEDAARHMAKEDAAQGIANEDAAHG 2266 V G +D A+G ED G Sbjct: 1268 PVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPG 1300 Score = 56.6 bits (135), Expect = 3e-07 Identities = 85/483 (17%), Positives = 132/483 (27%), Gaps = 13/483 (2%) Query: 1798 PDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQG 1857 P G + +G A D A G+P + G G+ E +G G Sbjct: 524 PQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPG 583 Query: 1858 IAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAN--- 1914 ED +G E+ +G+ E +G+ GI +G+ + Sbjct: 584 PPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQG 643 Query: 1915 EDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQG 1974 E G QG+ A G E QG G G +G Sbjct: 644 EPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKG 703 Query: 1975 IANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDV 2034 QG +G+ D + G+ D G ++ +G E Sbjct: 704 NQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKG---EDGFPGFKGDIGVKGDRGEVG 760 Query: 2035 ADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQ 2094 G ED G P G + + + +G Sbjct: 761 VPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGK-LGVPGLPGYPGRQGPKGSLGFPGFP 819 Query: 2095 AIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEV 2154 + + A G++ + +G E G + G + A G + D G E Sbjct: 820 GASGEKGARGLSGKSGPRG---ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGE- 875 Query: 2155 AAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVA 2214 +G+ G G KD + G + G + G QG A Sbjct: 876 --RGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAA 933 Query: 2215 NEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVH 2274 E G G E + G A ++ + A G G E + Sbjct: 934 GETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLP 993 Query: 2275 GIA 2277 G A Sbjct: 994 GTA 996 Score = 37.7 bits (86), Expect = 0.14 Identities = 73/380 (19%), Positives = 103/380 (27%), Gaps = 34/380 (8%) Query: 1927 VQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQ---- 1982 V+G + G+ +QG G G+ D A G Sbjct: 397 VEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRF 456 Query: 1983 GIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANED 2042 G D +A ++A + A A+ P G G + + G+ E Sbjct: 457 GSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLG---QPGSPGLKGES 513 Query: 2043 AAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAED----------AVQGITNEEA 2092 G Q + P G G A D A G+ D + G+ E+ Sbjct: 514 GDLGPQGPRGPQGLTGPPGKAG--RRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKG 571 Query: 2093 AQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANE------DA 2146 + G ED +G E+ +G+ E G+ G+ D Sbjct: 572 HRGDTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDG 631 Query: 2147 AQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVAN 2206 QG + QG QG QG+ G E QG G Sbjct: 632 PQGPKGSLGPQGEPGPPGQQGTPG---TQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG 688 Query: 2207 EDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAK------EDAAQGIAN 2260 G +G QG GV D R + ED G Sbjct: 689 PPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKG 748 Query: 2261 EDAAHGIANEDAVHGIANED 2280 + G E V G ED Sbjct: 749 DIGVKGDRGEVGVPGSRGED 768 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 91.3 bits (225), Expect = 1e-17 Identities = 248/1404 (17%), Positives = 395/1404 (28%), Gaps = 137/1404 (9%) Query: 784 EDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQG 843 ED G+ + + G G +G G E G A G Sbjct: 1451 EDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPG 1510 Query: 844 VAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAA-QAIAKPDAAHGIANEGVANEVAAQ 902 VA A G G E+ G + A+A P G + G A A Sbjct: 1511 VAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKG--DVGPAGPRGAT 1568 Query: 903 GIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDA 962 G+ E G+ G + + + G + G Sbjct: 1569 GVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVG 1628 Query: 963 AQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIAN 1022 +G EV +G G+ + +G+ V+G + QG ED +G Sbjct: 1629 PRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPG 1688 Query: 1023 EVAAHGI-------------------ANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQ 1063 G A E G ++ +G + G E ++ Sbjct: 1689 SSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIE 1748 Query: 1064 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANE- 1122 G QG + +G A E +G D G+ + A G + + G A + Sbjct: 1749 GFRGPPGPQG---DPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDP 1805 Query: 1123 --DAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQ 1180 D + G+ E + G + + G ED G+ + G ED +G + A Sbjct: 1806 GRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGAS 1865 Query: 1181 GIAHEDAVQGIANEDAV--------------------HGVAKEVAAHGVANEDAAHAIAK 1220 G D +G + GV G E + Sbjct: 1866 GREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQG 1925 Query: 1221 PDAARGIANE----------VAAQGIATEDVADGIANEDAAHGVANEV--AAHGISKEDA 1268 RG+ E + GI + + + D + G V G + Sbjct: 1926 LPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSG 1985 Query: 1269 VQGIANEDAAQGIAKEDAVQGIANEDAAQG-----IAKEDP-----VQGVANEDPIQGVA 1318 QG ++ G E ++G + QG + + P + G + I G+ Sbjct: 1986 EQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLP 2045 Query: 1319 NEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDA-----AQDIANEDAAQGISK 1373 G A +G E G D G+ ++ ++ G+S Sbjct: 2046 GRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSG 2105 Query: 1374 EDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANE----- 1428 E G+ A+G + QG + V G+ + G +D G+ E Sbjct: 2106 EQGPPGL---KGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAG 2162 Query: 1429 -------DAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAK 1481 G V HG A G+A QG + G G+ Sbjct: 2163 PEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPG-RGLTG 2221 Query: 1482 EVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQG 1541 A G+ + P + G+ +V G DG + +D G + G Sbjct: 2222 PTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPG 2281 Query: 1542 IANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPD 1601 + V G G V G E G + D + A D + + P Sbjct: 2282 LPGPVGPKGEPGPTGAPGQA-VVGLPGAKGEKGAPGGLAGDLVGEPGAKGD--RGLPGPR 2338 Query: 1602 AAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIA 1661 G A +D +G +G V G G+ Sbjct: 2339 GEKGEAGRAGEPGDPGEDGQKGAPGPKGFKG----------DPGVGVPGSPGPPGPPGVK 2388 Query: 1662 NEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQ 1721 + G+ V G + G E+ G + E + G + + G Sbjct: 2389 GDLGLPGLPGAPGVVGFPGQTGPRG---EMGQPGPSGERGLAGPPGREGIPGPLGPPGPP 2445 Query: 1722 GVAHEDAVQGIANEDAAHGI-----TNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHS 1776 G G+ + G+ E GI ED G + G Sbjct: 2446 GSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERG 2505 Query: 1777 VAKEVAAHGVANEDAAHA-IAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEV 1835 +V + G+ + A I P RG ++ +G G+ + G + Sbjct: 2506 EKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERG------PRGLDGDKGPRGDNGDP 2559 Query: 1836 AAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIA 1895 G E +G A +G+ G A G +D V GI E G Sbjct: 2560 GDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFM 2619 Query: 1896 NEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQ 1955 +G A + E +G + G+A G E V G + + Sbjct: 2620 GPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMG---EPGVPGQSGAPGKE 2676 Query: 1956 GIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPD 2015 G+ G + +G E +G G + D G A P Sbjct: 2677 GLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGND---GSAGPPGPPGSVGPR 2733 Query: 2016 AARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDV 2075 G+ + +G E V G A G E A P G A Sbjct: 2734 GPEGLQGQKGERGPPGERVV-GAPGVPGAPGERGEQGRPGPAGPRGEKGEA--------- 2783 Query: 2076 ADGIAEDAVQGITNEEAAQAIAKQ 2099 + ED ++G +E +Q A Q Sbjct: 2784 --ALTEDDIRGFVRQEMSQHCACQ 2805 Score = 89.4 bits (220), Expect = 4e-17 Identities = 229/1274 (17%), Positives = 371/1274 (29%), Gaps = 105/1274 (8%) Query: 1013 NEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQ 1072 +ED A G+ + + G G +G + G E G A Sbjct: 1450 SEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLP 1509 Query: 1073 GIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEV 1132 G+A A+G G E G + A G A P +G + G Sbjct: 1510 GVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGP-KGEKGDVGPAGPRGAT 1568 Query: 1133 EVQG--------VAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAH 1184 VQG + + +G + G+ G + +G G Sbjct: 1569 GVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVG 1628 Query: 1185 EDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADG 1244 G E G + G A E + RG E QG ED +G Sbjct: 1629 PRGRDGEVGEKGDEGPPGDPGLPGKAGE---RGLRGAPGVRGPVGEKGDQGDPGEDGRNG 1685 Query: 1245 IANEDAAHGVANEVAAHGI----------SKEDAVQGIANEDAAQGIAKEDAVQGIANED 1294 G E G ++E G ++ +G + + G E Sbjct: 1686 SPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGER 1745 Query: 1295 AAQGIAKEDPVQGVANEDP-IQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGI 1353 +G QG DP ++G A E +G D G+ + A G + + A G Sbjct: 1746 GIEGFRGPPGPQG----DPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGK 1801 Query: 1354 ANE---DAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANE 1410 A + D + E G S + G ED G+ ++ G ED +G + Sbjct: 1802 AGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGD 1861 Query: 1411 VEVQGVAHED------AVQGIANEDAAHGIANEVAA-----HGIANEDAAQGIANEDAAQ 1459 G D GI G+ V G+ +G E ++ Sbjct: 1862 SGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSK 1921 Query: 1460 GIAHEDAVQGIANE-DAVHGVAKEVAAHGVA-----------NEDAAHAIAKPDAARGIA 1507 G +G+ E +V V + + G+ +E + + P+ RG Sbjct: 1922 GEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPK 1981 Query: 1508 NEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAH 1567 + QG ++ G E G + QG G+A+ + Sbjct: 1982 GDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQG------PPGLALGE-----------R 2024 Query: 1568 GVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQ 1627 G + G + + + +P G E +D G+ Sbjct: 2025 GPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRP-GERGERGEKGERGEQGRDGPPGLPGT 2083 Query: 1628 DAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1687 G +S ++ G++ E G+ A+G + QG + V G+ Sbjct: 2084 PGPPG----PPGPKVSVDEPGPGLSGEQGPPGL---KGAKGEPGSNGDQGPKGDRGVPGI 2136 Query: 1688 AKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAA 1747 + G +D G+ E + G + +QG +G HG A Sbjct: 2137 KGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQG------PRGPPGPVGGHGDPGPPGA 2190 Query: 1748 HGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANE 1807 G+A QG + G + A G+ + P + G+ + Sbjct: 2191 PGLAGPAGPQGPSGLKGEPGETGPPG-RGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQ 2249 Query: 1808 VAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGV 1867 V G DG +D G + G+ +G A G A + G Sbjct: 2250 VGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVG-LPGA 2308 Query: 1868 ANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAV 1927 E G D V G G+ +G A ED +G Sbjct: 2309 KGEKGAPGGLAGDLV-GEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGF 2367 Query: 1928 QGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHE 1987 +G D G+ G G+ A G+ G E G + E Sbjct: 2368 KG----DPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGE 2423 Query: 1988 DAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIAT-----EDVADGIANED 2042 + G + + G P A G+ + G+ E GI ED Sbjct: 2424 RGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGED 2483 Query: 2043 AAHGVANEDAAQAIAKPDAAHGIANE--GIATEDVADGIAEDAV-QGITNEEAAQAIAKQ 2099 G ++ + + P + G E + + + + AV G A+ + Sbjct: 2484 GRPG---QEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGE 2540 Query: 2100 DAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGV 2159 G+ + +G + +G E G A G+ G A G Sbjct: 2541 RGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGS 2600 Query: 2160 ANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVA---NE 2216 +D V G+ E G ++G A G+ E G A G+A E Sbjct: 2601 PGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGE 2660 Query: 2217 VAAQGVANEDAAQG 2230 + GV + A G Sbjct: 2661 MGEPGVPGQSGAPG 2674 Score = 87.4 bits (215), Expect = 1e-16 Identities = 260/1449 (17%), Positives = 399/1449 (27%), Gaps = 130/1449 (8%) Query: 75 QGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANE 134 +G + G E G A GVA A+G G E G + Sbjct: 1482 RGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGD 1541 Query: 135 DAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQGI 194 AV G AV G E G A A G+ E + + + +G Sbjct: 1542 PAVVG----PAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLV-------LPGDPGPKGD 1590 Query: 195 SKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAV 254 + G+ G + +G G G E +G + + Sbjct: 1591 PGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGL 1650 Query: 255 QGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE 314 G A E G+ G E QG ED G +G E G Sbjct: 1651 PGKAGE---RGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGR 1707 Query: 315 VAAHGV-ANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKEVTAHG 373 + G A E + G + G E +G G + G Sbjct: 1708 LVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQG---DPGVRG 1764 Query: 374 VANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEV 433 A E +G D G+ D A P +G A + G D G+ E Sbjct: 1765 PAGEKGDRGPPGLDGRSGL----DGKPGAAGPSGPNGAAGKA---GDPGRDGLPGLRGEQ 1817 Query: 434 AAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVA 493 G S + G ED G+ ++ G ED +G E G + G Sbjct: 1818 GLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKG---EKGDSGASGREGRDGPK 1874 Query: 494 NKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAH 553 + A I P G+ V G V G G G+ E Sbjct: 1875 GERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGG-TGPKGDRGETGSKGEQGLPGERGLR 1933 Query: 554 AIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANED 613 +P + + + T GI + + + D + G + + + +G + Sbjct: 1934 --GEPGSVPNVDRLLETAGIKASALREIVETWDESSG-------SFLPVPERRRGPKGDS 1984 Query: 614 AVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGI 673 G ++ G E G + QG P A G Sbjct: 1985 GEQGPPGKEGPIGFPGERGLKGDRGDPGPQG---------------------PPGLALGE 2023 Query: 674 ANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAV 733 G+A E GI G+ G + +G E +G D Sbjct: 2024 RGPPGPSGLAGEPGKPGI------PGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGP 2077 Query: 734 QGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANE 793 G+ G V+ ++P G++ E QG +G + QG + Sbjct: 2078 PGLPGTPGPPG----PPGPKVSVDEPGPGLSGE---QGPPGLKGAKGEPGSNGDQGPKGD 2130 Query: 794 DAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGV 853 GI + G +D G+ E G + + G +G V HG Sbjct: 2131 RGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQG------PRGPPGPVGGHGD 2184 Query: 854 TNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGI 913 G+ A P G+ E +G+ A G+ Sbjct: 2185 PGPPGAPGLAGP----------------AGPQGPSGLKGEPGETGPPGRGLTGPTGAVGL 2228 Query: 914 -AKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAA 972 G+ + + + Q G + +D G + G+ V Sbjct: 2229 PGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGP 2288 Query: 973 QGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANE 1032 +G G A + G E G D + G G+ G A Sbjct: 2289 KGEPGPTGAPGQA-VVGLPGAKGEKGAPGGLAGDLV-GEPGAKGDRGLPGPRGEKGEAGR 2346 Query: 1033 DAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGI 1092 G ED +G G V G G+ + G+ V G Sbjct: 2347 AGEPGDPGEDGQKGAPGPKGFKG-DPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGF 2405 Query: 1093 ANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAA 1152 + G E+ G + E + G + + G G G+ + Sbjct: 2406 PGQTGPRG---EMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGD 2462 Query: 1153 HGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANE 1212 G V G E GI ED G + G G +V + G+ + Sbjct: 2463 PG----VGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGD 2518 Query: 1213 DAAHA-IAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQG 1271 A I P RG A G E G+ + G + + +G Sbjct: 2519 KGDSAVILGPPGPRG---------------AKGDMGERGPRGLDGDKGPRGDNGDPGDKG 2563 Query: 1272 IANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDA 1331 E +G A ++G+ G A G +D + G+ E G Sbjct: 2564 SKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRG 2623 Query: 1332 VQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAK 1391 ++G A G+ E +G A +A G E V G + +G+ Sbjct: 2624 LKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMG---EPGVPGQSGAPGKEGLIG 2680 Query: 1392 EDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQG 1451 +G + +G E +G G + D + G + G + QG Sbjct: 2681 PKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQG 2740 Query: 1452 IANEDAAQG--IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANE 1509 E G + V G E G G E A D RG + Sbjct: 2741 QKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGE----AALTEDDIRGFVRQ 2796 Query: 1510 VATQGIATE 1518 +Q A + Sbjct: 2797 EMSQHCACQ 2805 Score = 86.7 bits (213), Expect = 3e-16 Identities = 263/1476 (17%), Positives = 424/1476 (28%), Gaps = 145/1476 (9%) Query: 419 GIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANED 478 G A E +G + G+ G+A A+G G E G + Sbjct: 1489 GEAGEKGERGPPGPAGSRGLP------GVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDP 1542 Query: 479 AVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVA 538 AV G A G + A P A G+ E G+ + + G Sbjct: 1543 AVVGPA----VAGPKGEKGDVGPAGPRGATGVQGERGPPGLV-------LPGDPGPKGDP 1591 Query: 539 NEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVH 598 + G+ + P G G DG E G + + Sbjct: 1592 GDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLP 1651 Query: 599 GVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANE 658 G A E ++G V G E QG E +G +G E G Sbjct: 1652 GKAGERGLRGAPG---VRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRL 1708 Query: 659 DAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGI 718 A+ G + G + G E +G G + V+G Sbjct: 1709 VDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQG---DPGVRGP 1765 Query: 719 ANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANE---DPVQGVANEDVVQGVANE 775 A E +G D G+ + G + A G A + D + G+ E + G + Sbjct: 1766 AGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGP 1825 Query: 776 VEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGV 835 + G ED G+ ++ G E G + A G D +G E G+ Sbjct: 1826 PGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKG---ERGAPGI 1882 Query: 836 ANEDAAQGVAKEVTA-----------------HGVTNEDAVQGVVNEEALHGVVANEDAA 878 G+ V G T QG+ E L G Sbjct: 1883 LGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRG-------- 1934 Query: 879 QAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHS 938 + + P+ + G+ + + T D E + + + Sbjct: 1935 EPGSVPNVDRLLETAGIKASALREIVETWD---------------ESSGSFLPVPERRRG 1979 Query: 939 ITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVE 998 + QG ++ G E +G + QG G G+A E Sbjct: 1980 PKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPG--LALGERGPPGPSGLAGE-- 2035 Query: 999 VQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHG--- 1055 K I G+ G A G E +G D G+ G Sbjct: 2036 ----PGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPG 2091 Query: 1056 --ISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANE 1113 +S ++ G++ E G+ A+G + QG + V G+ + G + Sbjct: 2092 PKVSVDEPGPGLSGEQGPPGL---KGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQ 2148 Query: 1114 DPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGI 1173 D G+ E + G + +QG G V HG A G+ Sbjct: 2149 DGNPGLPGERGMAGPEGKPGLQG---------------PRGPPGPVGGHGDPGPPGAPGL 2193 Query: 1174 ANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAA 1233 A QG + G G+ A G+ + P + G+ +V Sbjct: 2194 AGPAGPQGPSGLKGEPGETGPPG-RGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGE 2252 Query: 1234 QGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIA---------KE 1284 G DG + +D G + G+ +G A G A ++ Sbjct: 2253 TGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEK 2312 Query: 1285 DAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGI 1344 A G+A + + AK D +G+ +G A G ED +G G Sbjct: 2313 GAPGGLAGDLVGEPGAKGD--RGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKG- 2369 Query: 1345 ANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAV 1404 D G+ G+ G+ G E G + E + Sbjct: 2370 ---DPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGL 2426 Query: 1405 QGVANEVEVQGVAHEDAVQGIANEDAAHGIANE-----VAAHGIANEDAAQGIANEDAAQ 1459 G + G G A G+ + V G E GI ED Sbjct: 2427 AGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRP 2486 Query: 1460 GIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHA-IAKPDAARGIANEVATQGIATE 1518 G + G G +V + G+ + A I P RG ++ +G Sbjct: 2487 GQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERG---- 2542 Query: 1519 DVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGV 1578 G+ + G + +G E G A ++G++ G A G Sbjct: 2543 --PRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGS 2600 Query: 1579 VNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVA 1638 +D + + E P G A + + +G A G+A Sbjct: 2601 PGKDGVPG-IRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKG 2659 Query: 1639 AHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVAN 1698 G E V G + +G+ +G + +G E G G + Sbjct: 2660 EMG---EPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSG 2716 Query: 1699 EDPVQGVANEDAVQGVANEVEVQGVAHE-----DAVQGIANEDAAHGITNEVAAHGIANE 1753 D G G +QG E + V G A G E G A Sbjct: 2717 NDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGP 2776 Query: 1754 DAAQGIA--HEDAVQGIANEDAVHSVAKEVAAHG--VANEDAAHAIAKPDAARGIANEVA 1809 +G A ED ++G ++ +++ A G +A+ D A + V Sbjct: 2777 RGEKGEAALTEDDIRGFVRQE----MSQHCACQGQFIASGSRPLPSYAADTAGSQLHAVP 2832 Query: 1810 AQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDA 1845 ++ + + +P ED + +E + +A Sbjct: 2833 VLRVSHAEEEERVPPEDDEYSEYSEYSVEEYQDPEA 2868 Score = 83.2 bits (204), Expect = 3e-15 Identities = 229/1245 (18%), Positives = 362/1245 (29%), Gaps = 145/1245 (11%) Query: 67 GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126 G+T G + +G G G E +G + G A E Sbjct: 1598 GLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGER 1657 Query: 127 AVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDI---------- 176 ++G V+G E QG ED +G +G E Sbjct: 1658 GLRGAPG---VRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPG 1714 Query: 177 AKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGI-----AKEDP-VQGVANEDPVQGV 230 A+E ++ +G + + G E +G + DP V+G A E +G Sbjct: 1715 AREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGP 1774 Query: 231 ANEDAVQGVANEVEVQGVAHEDAVQGIANE---DAAHGITNEVAAHGIANEDAAQGIANE 287 D G+ + G + + G A + D G+ E G + G E Sbjct: 1775 PGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGE 1834 Query: 288 DAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANED------AAHAIAKPDAAHGIANE 341 D G+ ++ G ED G + A G D A I P G+ Sbjct: 1835 DGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGLPGP 1894 Query: 342 VATQGIATEDVADGIANEDAAHGVAKEVTAHGVANEDAVQG----VVNEDAL---HGVVA 394 V G V G G G+ E ++G V N D L G+ A Sbjct: 1895 VGPPGQGFPGVPGG-TGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKA 1953 Query: 395 ----------NEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAV 444 +E + + P+ G + G ++ G E G + Sbjct: 1954 SALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGP 2013 Query: 445 QGIANEDAAQGIAHEDAAQGIAHE---DAVQGIANEDAVHGVAKEVAAHGVANKDAAHAI 501 QG A G G+A E + G+ G A G + Sbjct: 2014 QG--PPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGE 2071 Query: 502 AKPDAARGIANEVAAQG-----IATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIA 556 D G+ G ++ ++ G++ E G+ G E ++ Sbjct: 2072 QGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGL------KGAKGEPGSNGDQ 2125 Query: 557 KPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAV- 615 P G+ GI + G +D G+ E + G + +QG Sbjct: 2126 GPKGDRGV------PGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPGPV 2179 Query: 616 --HGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGI 673 HG A G+A G A G+ E G + + P A G+ Sbjct: 2180 GGHGDPGPPGAPGLA------GPAGPQGPSGLKGEPGETG-----PPGRGLTGPTGAVGL 2228 Query: 674 ANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGI------ 727 G+ + G+ + G G S +D +G + G+ Sbjct: 2229 PGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGP 2288 Query: 728 --------AHEDAVQGI----ANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANE 775 A AV G+ + A G+A ++ A D +G+ +G A Sbjct: 2289 KGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGD--RGLPGPRGEKGEAGR 2346 Query: 776 VEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGV 835 G ED +G G V G GV + G+ V G Sbjct: 2347 AGEPGDPGEDGQKGAPGPKGFKGDPG-VGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGF 2405 Query: 836 ANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAA-------- 887 + +G E+ G + E + G E + G + ++ P A+ Sbjct: 2406 PGQTGPRG---EMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGD 2462 Query: 888 HGIANEGVANEVAAQGIATEDVADGIAKDAAHGIT-----------KEEAAQAIAKQDAA 936 G+ G E GI ED G ++ G+T K + A K D Sbjct: 2463 PGVGLPGPRGERGEPGIRGEDGRPG--QEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKG 2520 Query: 937 HSIT--------------NEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVH 982 S E +G+ + G + +G E +G A + Sbjct: 2521 DSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLR 2580 Query: 983 GVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANED 1042 G+ G A G KD + GI E G + G+ E +G D Sbjct: 2581 GLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGF---MGPRGLKGERGVKGACGLD 2637 Query: 1043 AAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVA 1102 +G E G +G E G + +G+ +G + G Sbjct: 2638 GEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQ 2697 Query: 1103 KEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAH 1162 E G G + D G G + +QG E G V A Sbjct: 2698 GEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPG-ERVVGAP 2756 Query: 1163 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAH 1207 G+ +G G E + +D V +E++ H Sbjct: 2757 GVPGAPGERGEQGRPGPAGPRGEKGEAALTEDDIRGFVRQEMSQH 2801 Score = 72.4 bits (176), Expect = 5e-12 Identities = 203/1124 (18%), Positives = 323/1124 (28%), Gaps = 94/1124 (8%) Query: 67 GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126 G E ++G QG + G A E G D G+ + A G + + Sbjct: 1740 GAPGERGIEGFRGPPGPQG---DPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPN 1796 Query: 127 AVQGVANE---DAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQ 183 G A + D + G+ E + G + G ED G+ ++ ED + Sbjct: 1797 GAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRK 1856 Query: 184 DIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANE--------DPVQGVANEDA 235 + A G D +G E A GI G+ V G Sbjct: 1857 GEKGDSGASGREGRDGPKG---ERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKG 1913 Query: 236 VQGVANEVEVQGVAHEDAVQG----IANED---AAHGITNEVAAHGIANEDAAQG--IAN 286 +G QG+ E ++G + N D GI + D + G + Sbjct: 1914 DRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPV 1973 Query: 287 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQG 346 + +G + QG ++ G E G + P A G G Sbjct: 1974 PERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQ--GPPGLALGERGPPGPSG 2031 Query: 347 IATEDVADGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDA-------A 399 +A E GI G E G E +G E G Sbjct: 2032 LAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPG 2091 Query: 400 QAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHE 459 ++ + G++ E G+ A+G G + V GI + G + Sbjct: 2092 PKVSVDEPGPGLSGEQGPPGL---KGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQ 2148 Query: 460 DAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGI 519 D G+ E + G + + G G H P A G+A QG Sbjct: 2149 DGNPGLPGERGMAGPEGKPGLQG------PRGPPGPVGGHGDPGPPGAPGLAGPAGPQGP 2202 Query: 520 ATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVA 579 + G G+ A G+ + P + G+ +V G Sbjct: 2203 SGLKGEPGETGPPG-RGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGR 2261 Query: 580 DGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANE 639 DG + +D G G+ +G G A V G E Sbjct: 2262 DGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQA----------VVGLPGAKGE 2311 Query: 640 DAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQG 699 G + D + A D + + P G A G ED +G +G Sbjct: 2312 KGAPGGLAGDLVGEPGAKGD--RGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKG 2369 Query: 700 IANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDP 759 V G G+ + G+ V G + G E+ G + E Sbjct: 2370 DPG-VGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRG---EMGQPGPSGERG 2425 Query: 760 VQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVAN 819 + G + + G G G+ + G V G E G+ Sbjct: 2426 LAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPG----VGLPGPRGERGEPGIRG 2481 Query: 820 EDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQ 879 ED G ++ G+ ++G E +G V L G ++ + Sbjct: 2482 EDGRPG---QEGPRGLTGPPGSRG------------ERGEKGDVGSAGLKG---DKGDSA 2523 Query: 880 AIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAA-HGITKEEAAQAIAKQDAAHS 938 I P G +G E +G+ + G D G E + A Sbjct: 2524 VILGPPGPRGA--KGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRG 2581 Query: 939 ITNEDAAQGVANEDAAHGVANEDAAQGVANE------VAAQGVANEDAVHGVANEDAVQG 992 + G A G +D G+ E + +G+ E V G D +G Sbjct: 2582 LLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKG 2641 Query: 993 VANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVA 1052 E G +G E G + G+ +G + +G E Sbjct: 2642 DKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKG 2701 Query: 1053 AHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVAN 1112 G G + D + G + G + +QG E G + V A GV Sbjct: 2702 ERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPG-ERVVGAPGVPG 2760 Query: 1113 EDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIA 1156 +G G E + + ED ++G ++ + A Sbjct: 2761 APGERGEQGRPGPAGPRGE-KGEAALTEDDIRGFVRQEMSQHCA 2803 Score = 58.5 bits (140), Expect = 7e-08 Identities = 186/1046 (17%), Positives = 305/1046 (29%), Gaps = 110/1046 (10%) Query: 63 DAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGV 122 D G+ E + G + G ED G+ + G ED +G + A G Sbjct: 1808 DGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSGASGR 1867 Query: 123 ANEDAVQGVANEDAVQGVANEDAV-----------------------QGIANEDAAHGIA 159 D +G + G + +G G+ Sbjct: 1868 EGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLP 1927 Query: 160 NEDAAQG----IANEDAAQDIA--KEDAAQDIA---NEDAAQGISKEDAVQGIANEDAAQ 210 E +G + N D + A K A ++I +E + + + +G + Q Sbjct: 1928 GERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQ 1987 Query: 211 G-IAKEDPVQGVANEDPVQGVANEDAVQGVAN-EVEVQGVAHEDAVQGIANEDAAHGITN 268 G KE P+ G E ++G + QG + +G + G + G+ Sbjct: 1988 GPPGKEGPI-GFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPG 2046 Query: 269 EVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHG-----VAKEVAAHGVANE 323 G A +G E +G D G+ G V+ + G++ E Sbjct: 2047 RAGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGE 2106 Query: 324 DAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKEVTAHGVANEDAVQGV 383 + A G QG + GI + G + G+ E + G Sbjct: 2107 QGPPGL---KGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGP 2163 Query: 384 VNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDA 443 + L G + P HG A G+A QG + G + Sbjct: 2164 EGKPGLQG-------PRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPG 2216 Query: 444 VQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKD------- 496 +G+ A G+ G+ G+ + G G + KD Sbjct: 2217 -RGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPG 2275 Query: 497 --AAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHA 554 + + P +G A G A + + A G+A ++ A D Sbjct: 2276 VPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGD--RG 2333 Query: 555 IAKPDAAHGIANEVATQGIATEDVADGIANE-----DAAHGVANEVAVHGVAIEDAVQGV 609 + P G A G ED G D GV G G+ Sbjct: 2334 LPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGL 2393 Query: 610 ANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDA 669 GV G E+ G + E + G + + G + ++ P A Sbjct: 2394 PGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGA 2453 Query: 670 AHGIANE-----VAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAA 724 + G+ + V G E GI ED G ++ +G+ + Sbjct: 2454 S-GLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPG------------QEGPRGLTGPPGS 2500 Query: 725 QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHE 784 +G E G A G + + G +G E +G+ + +G + Sbjct: 2501 RGERGEKGDVGSAGLKGDKGDSAVIL--GPPGPRGAKGDMGERGPRGLDGDKGPRGDNGD 2558 Query: 785 DAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGV 844 +G E G A G+ G A G +D V G+ E G Sbjct: 2559 PGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGF 2618 Query: 845 AKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGI 904 + G+ E V+G + E + A P G+A G E+ G+ Sbjct: 2619 ---MGPRGLKGERGVKGACG-------LDGEKGDKGEAGPPGRPGLA--GHKGEMGEPGV 2666 Query: 905 ATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQ 964 + A G G+ + + Q E +G G + D + Sbjct: 2667 PGQSGAPG-----KEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSA 2721 Query: 965 GVANEVAAQGVANEDAVHGVANEDAVQG--VANEVEVQGIAHKDAIQGIANEDAAHGIAN 1022 G + G + + G E G V V G + QG G Sbjct: 2722 GPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKG 2781 Query: 1023 EVAAHGIANEDAAQGIANEDAAQGIA 1048 E A ED +G ++ +Q A Sbjct: 2782 EAA----LTEDDIRGFVRQEMSQHCA 2803 Score = 43.9 bits (102), Expect = 0.002 Identities = 86/461 (18%), Positives = 124/461 (26%), Gaps = 27/461 (5%) Query: 1815 TEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQ 1874 +ED A G+P + + G G +G G E G A + Sbjct: 1450 SEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLP 1509 Query: 1875 GVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQD 1934 GVA +G G E G + A A G E G A Sbjct: 1510 GVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVG----PAVAGPKGEKGDVGPAGPR 1565 Query: 1935 AAQGIAKEDAVQGIA--NEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQG 1992 A G+ E G+ + +G + G+ G + +G G Sbjct: 1566 GATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPG 1625 Query: 1993 IANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDA 2052 G E P G+ + +G+ G E G ED Sbjct: 1626 PVGPRGRDGEVGEKGDEG---PPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDG 1682 Query: 2053 AQAIAKPDAAHGIANEGIATE------DVADGIAEDAVQGITNEEAAQAIAKQDAAHGIT 2106 G E D G E G +E + G Sbjct: 1683 RNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAP 1742 Query: 2107 KEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQ 2166 E +G QG + G A E G D G+ + A G + + Sbjct: 1743 GERGIEGFRGPPGPQG---DPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAA 1799 Query: 2167 GVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANED 2226 G A G +D + G+ E G + G ED G+ + G ED Sbjct: 1800 GKA------GDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGED 1853 Query: 2227 AAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGI 2267 +G + G D + E A GI G+ Sbjct: 1854 GRKGEKGDSGASGREGRDGPK---GERGAPGILGPQGPPGL 1891 Score = 38.1 bits (87), Expect = 0.10 Identities = 86/462 (18%), Positives = 129/462 (27%), Gaps = 35/462 (7%) Query: 1821 GIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHED 1880 G+P + G V G E +ED A G+ + G G Sbjct: 1424 GLPGLPGSPGPQGPVGPPGKKGEKG----DSEDGAPGLPGQPGSPGEQGPRGPPGAIGPK 1479 Query: 1881 AVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIA 1940 +G G E G A +A A+G G + G Sbjct: 1480 GDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRP 1539 Query: 1941 KEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIA--HEDAVQGIANEDA 1998 + AV G A G E G A A G+ E G+ + +G + Sbjct: 1540 GDPAVVG----PAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRG 1595 Query: 1999 VHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAK 2058 G+ + P +G G DG E G + A Sbjct: 1596 PIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAG 1655 Query: 2059 PDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEV 2118 G V+G E+ Q +D +G +G E Sbjct: 1656 ERGLRGAPG----------------VRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEP 1699 Query: 2119 AAQGVANE--DAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQG 2176 G D G A E G ++ +G + G E ++G QG Sbjct: 1700 GPPGPPGRLVDTGPG-AREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQG 1758 Query: 2177 IAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANE---DAAQGVAN 2233 ++G A E +G G+ + A G + A G A + D G+ Sbjct: 1759 ---DPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRG 1815 Query: 2234 EVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVHG 2275 E + G + ED G+ ++ G ED G Sbjct: 1816 EQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKG 1857 Score = 37.0 bits (84), Expect = 0.23 Identities = 81/413 (19%), Positives = 115/413 (27%), Gaps = 37/413 (8%) Query: 1896 NEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQ 1955 +ED A G+ + + G +G G E G A Sbjct: 1450 SEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLP 1509 Query: 1956 GIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPD 2015 G+A A G G E G + AV G AV G E A P Sbjct: 1510 GVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVG----PAVAGPKGEKGDVGPAGPR 1565 Query: 2016 AARGIANEVAAQGIATE-------DVAD-------GIANEDAAHGVANEDAAQAIAKPDA 2061 A G+ E G+ D D G A G E P Sbjct: 1566 GATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPG 1625 Query: 2062 AHGI-ANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAA 2120 G +G E +G D G+ + + + G E QG E Sbjct: 1626 PVGPRGRDGEVGEKGDEGPPGDP--GLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGR 1683 Query: 2121 QGVANEDAAHGVANEVAAHGV----------ANEDAAQGVANEVAAQGVANEDAVQGVAN 2170 G G E G A E G + +G + + G Sbjct: 1684 NGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPG 1743 Query: 2171 EVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQG 2230 E ++G QG + +G A E G D G+ + A G + + A G Sbjct: 1744 ERGIEGFRGPPGPQG---DPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAG 1800 Query: 2231 VANEVA---VHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVHGIANED 2280 A + + G+ E + G ED G+ ++ G ED Sbjct: 1801 KAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGED 1853 >gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens] Length = 1714 Score = 87.8 bits (216), Expect = 1e-16 Identities = 167/949 (17%), Positives = 266/949 (28%), Gaps = 79/949 (8%) Query: 606 VQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAA---- 661 V G + + G+ QG G+ + G+ E + G N + Sbjct: 547 VPGEKGDQGLSGLMGPPGMQG------DKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPG 600 Query: 662 -QAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIAN 720 Q +A P+ G A G G + +GI G G Sbjct: 601 RQGLAGPEGNPG---PKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFG 657 Query: 721 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQG 780 + G+ + G G+ V G + G G++ + G Sbjct: 658 DRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGP------MGLSGNKGLPG 711 Query: 781 IAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDA 840 I + QG A E G + A G+ +G + G + + G + Sbjct: 712 IKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRG---KSGPSGQTGDPGLQGPSGPPG 768 Query: 841 AQGVAKEVTAHGVTNEDAVQGVVNEEA------LHGVVANEDAAQAIAKPDAAHGIANEG 894 +G ++ G + +G++ L G E A + +G Sbjct: 769 PEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKG 828 Query: 895 VANEVAAQGIATEDVADG----IAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVAN 950 A E +G+ E G I + G+ E + E + G Sbjct: 829 YAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKG------ERGSPGPLG 882 Query: 951 EDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQG 1010 GV GV + G+ G +G G+ + IQG Sbjct: 883 PQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQG 942 Query: 1011 IANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDA 1070 E G G +G + QG+ G+ E ++G+ + Sbjct: 943 AKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVG 1002 Query: 1071 AQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVAN 1130 G + G E +QG G A V G G E+ +QG Sbjct: 1003 PPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQG--- 1059 Query: 1131 EVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQG 1190 G+ +G+ ED G G G+ + GI + G Sbjct: 1060 ---KDGLKGVPGGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPG 1116 Query: 1191 IANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGI----- 1245 + G EV + G + + P ARG V G+ D GI Sbjct: 1117 KKGDKGQIGPTGEVGSRGPPGKIGK---SGPKGARGTRGAVGHLGLMGPDGEPGIPGYRG 1173 Query: 1246 -ANEDAAHGVANEVAAHGISKEDAV----------------QGIANEDAAQGIAKEDAVQ 1288 + G+ G ED+ QG E A+G V Sbjct: 1174 HQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVP 1233 Query: 1289 GIANEDAAQGIAKE---DPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIA 1345 G+ QG E QG+ E +G + G + + + G+ GI Sbjct: 1234 GLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQ 1293 Query: 1346 NEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQ 1405 A GI+ + GI G+A G+ G+ +Q Sbjct: 1294 GYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGS---SGLPGSPGIQ 1350 Query: 1406 GVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHED 1465 G E QG+ + +QG A G G+ + G+ QG Sbjct: 1351 GPKGE---QGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPK 1407 Query: 1466 AVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQG 1514 +G A + G + G I P G E +G Sbjct: 1408 GPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRG 1456 Score = 83.6 bits (205), Expect = 2e-15 Identities = 174/998 (17%), Positives = 285/998 (28%), Gaps = 101/998 (10%) Query: 1298 GIAKEDPVQGVANEDPIQGVANEVEVQG---VAHEDAVQGIANEDAAHGIANEDAAQGIA 1354 G + PV G + + G+ +QG + + G+ E G A + G Sbjct: 540 GFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYP 599 Query: 1355 NEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAV---QGVANEV 1411 Q +A + G G E G E + G+ + QG + Sbjct: 600 GR---QGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDF 656 Query: 1412 EVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIA 1471 +G A D G+ G + G GI G++ + GI Sbjct: 657 GDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIPGP---MGLSGNKGLPGIK 713 Query: 1472 NEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAH 1531 + G A E+ G + A + P RG + G + Sbjct: 714 GDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGP------------SGQTGDPGLQ 761 Query: 1532 GVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVA-- 1589 G + +G ++ + G + +G++ G QG + Sbjct: 762 GPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPR 821 Query: 1590 NEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQ 1649 + + A G+ EV K G G+ EV G E + Sbjct: 822 GKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPV------GLPGEVGMTGSIGEKGER 875 Query: 1650 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANED 1709 G QG +G+ G+ G+ V A G +G Sbjct: 876 GSPGPLGPQG------EKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSR 929 Query: 1710 AVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIA 1769 G+ E +QG E QG G T G + QG+ +G+ Sbjct: 930 GPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLP 989 Query: 1770 NEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAH 1829 E + + +V G E+ +G + G+ E A Sbjct: 990 GEPGLRGLQGDVGPPG---------------------EMGMEGPPGTEGESGLQGEPGAK 1028 Query: 1830 GVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANED 1889 G + G + E ++G +G+ +D ++GV +G+ ED +G Sbjct: 1029 GDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVPGG---RGLPGEDGEKGEMGLP 1085 Query: 1890 AAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIA 1949 G G+ + I + G + G + ++G G + Sbjct: 1086 GIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRG---PPGKIGKS 1142 Query: 1950 NEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAH 2009 A+G V G+ D GI QG + G+ G ED+ Sbjct: 1143 GPKGARGTRGAVGHLGLMGPDGEPGIPGYRGHQG---QPGPSGLPGPKGEKGYPGEDST- 1198 Query: 2010 AIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEG 2069 + P RG V QG E A+G G+ Q P G E Sbjct: 1199 -VLGPPGPRGEPGPVGDQGERGEPGAEGYKGHVGVPGLRGATGQQG---PPGEPGDQGE- 1253 Query: 2070 IATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAA 2129 QG+ E ++ + A G + + G+ + +G+ A Sbjct: 1254 ---------------QGLKGERGSEGNKGKKGAPGPSGKPGIPGLQGLLGPKGIQGYHGA 1298 Query: 2130 HGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQG---IAHKDAIQGI 2186 G++ G + G+ G+A GV + G I QG+ Sbjct: 1299 DGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGL 1358 Query: 2187 ANEDAAQGVANEVAAH---------GVANEDAAQGVANEVAAQGVANEDAAQGVANEVAV 2237 + QG A G+ + GV QG +G A V + Sbjct: 1359 PGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGI 1418 Query: 2238 HGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVHG 2275 G R +GI G E G Sbjct: 1419 SGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRG 1456 Score = 82.0 bits (201), Expect = 6e-15 Identities = 204/1212 (16%), Positives = 359/1212 (29%), Gaps = 90/1212 (7%) Query: 1021 ANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAA 1080 A ++ HGI A + I ED + V H IS +A + ++ +++ Sbjct: 324 AVDLTNHGI---QAKEMITEEDTQTNFSLSVTTHRIS--EAKMNTKEKFSSLLNMSDNIT 378 Query: 1081 QGIAHEDAVQGIA------------NEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGV 1128 Q H+D V G++ +D + + K + A+ NE ++ V Sbjct: 379 Q---HDDRVTGLSLFKKMPSILPQIKQDTITNLKKAITANLHTNELMEMQPILNTSLHRV 435 Query: 1129 ANEVEVQGVAHEDA-VQGIANEDAAHGIAN--EVAAHGIANEDAAQGIANEDAAQGIAHE 1185 NE V H D +G DA + I N E + + + + +G + Sbjct: 436 TNEPSVDN--HLDLRKEGEFYPDATYPIENSYETELYDYYYYEDLNTMLEMEYLRGPKGD 493 Query: 1186 DAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGI 1245 G + G + + G+ + G+ +G + Sbjct: 494 TGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLP------GLPGPKGPKGDPGFSPGQPV 547 Query: 1246 ANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPV 1305 E G++ + G+ + +G+ G+ E + G A + G + Sbjct: 548 PGEKGDQGLSGLMGPPGMQGD---KGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGRQGL 604 Query: 1306 QGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANE 1365 G +G + G A + +G G QG + + A Sbjct: 605 AGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDRGPAGL 664 Query: 1366 DAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGI 1425 D + G+ G + G P+ G A G++ + G+ + QG Sbjct: 665 DGSPGLVGGTGPPGFPGLRGSVGPV--GPI-GPAGIPGPMGLSGNKGLPGIKGDKGEQGT 721 Query: 1426 ANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAA 1485 A E G + A G+ +G + G + +QG + G ++ Sbjct: 722 AGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTG---DPGLQGPSGPPGPEGFPGDIGI 778 Query: 1486 HGVANEDAAHAIAK---PDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGI 1542 G + + P G+ +G G + G A E +G+ Sbjct: 779 PGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRGKPGQKGYAGEPGPEGL 838 Query: 1543 ANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVA--NEDAAQAIAKP 1600 EV G G + E G+ E + G + E + + Sbjct: 839 KGEVGDQGNI------GKIGETGPVGLPGEVGMTGSIGEKGERGSPGPLGPQGEKGVMGY 892 Query: 1601 DAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGI 1660 G+ + + A+G +G G+ E +QG E QG Sbjct: 893 PGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQGK 952 Query: 1661 ANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEV 1720 G +G + + G+ G+ E ++G+ + G E+ + Sbjct: 953 RGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGD---VGPPGEMGM 1009 Query: 1721 QGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKE 1780 +G + G+ E A G + G E +G +G+ +D + V Sbjct: 1010 EGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGLRGEPGAPGEEGLQGKDGLKGVP-- 1067 Query: 1781 VAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGI 1840 G+ ED G G+ + GIP + G + G Sbjct: 1068 -GGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGPEGIVGIPGQRGRPGKKGDKGQIGP 1126 Query: 1841 SKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAA 1900 + E +G + G +G + + G E + G G + Sbjct: 1127 TGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGPDGEPGIPGY------RGHQGQPGP 1180 Query: 1901 QGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANE 1960 G+ + ED+ + +G QG E A+G Sbjct: 1181 SGLPGPKGEKGYPGEDST-----------VLGPPGPRGEPGPVGDQGERGEPGAEGYKGH 1229 Query: 1961 VAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGI 2020 V G+ QG E QG QG+ E G + A + G+ Sbjct: 1230 VGVPGLRGATGQQGPPGEPGDQG------EQGLKGERGSEGNKGKKGAPGPSGKPGIPGL 1283 Query: 2021 ANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIA 2080 + +GI ADGI+ G + I G+A A G Sbjct: 1284 QGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGLAG--------APG-- 1333 Query: 2081 EDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHG 2140 V+G + + I G+ + QG AQG G+ + +G Sbjct: 1334 PPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYG 1393 Query: 2141 VANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVA 2200 V QG +G A + G + +G +GI G E Sbjct: 1394 VQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKG 1453 Query: 2201 AHGVANEDAAQG 2212 G +G Sbjct: 1454 FRGETGPQGPRG 1465 Score = 82.0 bits (201), Expect = 6e-15 Identities = 192/1127 (17%), Positives = 320/1127 (28%), Gaps = 108/1127 (9%) Query: 66 HGITNEDAVQGVANEVAAQGVANEDAAHGVAN--EVAAHGVANEDAAQGVANEVAAQGVA 123 H +TNE +V ++ +G DA + + N E + + + +G Sbjct: 433 HRVTNEPSVDNHL-DLRKEGEFYPDATYPIENSYETELYDYYYYEDLNTMLEMEYLRGPK 491 Query: 124 NEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQ 183 + G + G + + +GI G+ +G + Q Sbjct: 492 GDTGPPGPPGPAGIPGPSGKRGPRGIPGPHGNPGLPGLPGPKGPKGDPGFSP------GQ 545 Query: 184 DIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEV 243 + E QG+S + G +G+ + G+ E + G A G Sbjct: 546 PVPGEKGDQGLS---GLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYPGR- 601 Query: 244 EVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDA---AQGIAHEDAVQ 300 QG+A + G G E G E GI + QG + + Sbjct: 602 --QGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKGRQGFPGDFGDR 659 Query: 301 GIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANED 360 G A D G+ V G P G A G++ GI + Sbjct: 660 GPAGLDGSPGL---VGGTGPPGFPGLRGSVGPVGPIGPAGIPGPMGLSGNKGLPGIKGDK 716 Query: 361 AAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVA-----NEDAAQAIAKPDAAHGIANEV 415 G A E+ G + G+ + G + Q + P G ++ Sbjct: 717 GEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGPSGQTGDPGLQGPSGPPGPEGFPGDI 776 Query: 416 AAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIA 475 GI ++ +G + G ++G E+ G E +G + +G A Sbjct: 777 ---GIPGQNGPEGPKGLLGNRGPPGPPGLKGTQGEEGPIGAFGELGPRG---KPGQKGYA 830 Query: 476 NEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVH 535 E G+ EV G K G+ EV G + G E Sbjct: 831 GEPGPEGLKGEVGDQGNIGKIGETGPV------GLPGEVGMTG------SIGEKGERGSP 878 Query: 536 GVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEV 595 G GV + P G+ V +G G G+ E Sbjct: 879 GPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQ 938 Query: 596 AVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVV 655 + G E QG + G +G + G+ +G+ E L G+ Sbjct: 939 GIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQ 998 Query: 656 ANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAV 715 + G E+ G + G+ E A+G + G + E + Sbjct: 999 GDV-------------GPPGEMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGL 1045 Query: 716 QGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANE 775 +G +G+ +D ++G+ + G E G+ + G G+ Sbjct: 1046 RGEPGAPGEEGLQGKDGLKGVPGGRGLPGEDGEKGEMGLPG---IIGPLGRSGQTGLPGP 1102 Query: 776 VEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGV 835 + GI + G + G EV + G + G +G + G Sbjct: 1103 EGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGP 1162 Query: 836 ANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHG-IANEG 894 E G G + G+ + G + P G + ++G Sbjct: 1163 DGEPGIPGY------RGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQG 1216 Query: 895 VANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAA 954 E A+G G+ +G + Sbjct: 1217 ERGEPGAEGYKGHVGVPGL--------------------------------RGATGQQGP 1244 Query: 955 HGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANE 1014 G + QG+ E ++G + G + + + G+ QG+ IQG Sbjct: 1245 PGEPGDQGEQGLKGERGSEGNKGKKGAPGPSGKPGIPGL------QGLLGPKGIQGYHGA 1298 Query: 1015 DAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGI 1074 D G ++ G +G G G S GI QG+ Sbjct: 1299 DGISGNPGKIGPPGKQGLPGIRGGPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGL 1358 Query: 1075 ANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEV 1134 + QG QG G+ + +GV QG +G A V + Sbjct: 1359 PGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLTGFQGFPGPKGPEGDAGIVGI 1418 Query: 1135 QGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQG 1181 G +G GI G E +G E QG Sbjct: 1419 SGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGE---KGFRGETGPQG 1462 Score = 79.7 bits (195), Expect = 3e-14 Identities = 162/918 (17%), Positives = 263/918 (28%), Gaps = 63/918 (6%) Query: 563 GIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANED 622 G A + + G G G + G A + +G + G Sbjct: 588 GFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFK 647 Query: 623 AAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGI 682 QG + G A D G+V G + + P GI + G+ Sbjct: 648 GRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVG-PIGPAGIPGPM---GL 703 Query: 683 ANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAV 742 + GI + QG A E+ G + G+ +G + G + + Sbjct: 704 SGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRG---KSGPSGQTGDPGL 760 Query: 743 HGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANE 802 G + G + + G + +G+ +G ++G E+ G E Sbjct: 761 QGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGN---RGPPGPPGLKGTQGEEGPIGAFGE 817 Query: 803 VAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGV 862 + G + G + +G + G E G+ EV G E +G Sbjct: 818 LGPRGKPGQKGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGSIGEKGERGS 877 Query: 863 VNEEALHGVVANEDAAQAIAKPDAAHG-IANEGVANEVAAQGIATEDVADGIAKDAAHGI 921 G E P G I G+ V A+G G Sbjct: 878 PGPLGPQG----EKGVMGYPGPPGVPGPIGPLGLPGHVGARGPP--------GSQGPKGQ 925 Query: 922 TKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAV 981 + + E QG G +G + QG+ Sbjct: 926 RGSRGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGD 985 Query: 982 HGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANE 1041 G+ E ++G+ +V G + ++G + G+ E A G + G E Sbjct: 986 RGLPGEPGLRGLQGDVGPPG---EMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGE 1042 Query: 1042 DAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1101 +G G+ +D ++G+ +G+ ED +G + G G+ Sbjct: 1043 PGLRGEPGAPGEEGLQGKDGLKGVPG---GRGLPGEDGEKGEMGLPGIIGPLGRSGQTGL 1099 Query: 1102 AKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAA 1161 G+ + G + G EV +G + G A G V Sbjct: 1100 PGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSG---PKGARGTRGAVGH 1156 Query: 1162 HGIANEDAAQGIAN------EDAAQGIAHEDAVQGIANEDAV-------HGVAKEVAAHG 1208 G+ D GI + G+ +G ED+ G V G Sbjct: 1157 LGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQG 1216 Query: 1209 VANEDAAHAIAKPDAARGIANEVAAQGIATE---DVADGIANEDAAHGVANEVAAHGISK 1265 E A G+ QG E G+ E + G + A G S Sbjct: 1217 ERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQGEQGLKGERGSEGNKGKKGAPGPSG 1276 Query: 1266 EDAV---QGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVE 1322 + + QG+ QG D + G + G QG+ I+G Sbjct: 1277 KPGIPGLQGLLGPKGIQGYHGADGISGNPGKIGPPG------KQGLPG---IRGGPGRTG 1327 Query: 1323 VQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIAN 1382 + G V+G + + GI QG+ + Q AQG G+ Sbjct: 1328 LAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKG 1387 Query: 1383 EDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHG 1442 + G+ QG +G A V + G +G GI G Sbjct: 1388 QPGEYGVQGLTGFQGFPGPKGPEGDAGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTG 1447 Query: 1443 IANEDAAQGIANEDAAQG 1460 E +G E QG Sbjct: 1448 PRGE---KGFRGETGPQG 1462 Score = 75.9 bits (185), Expect = 4e-13 Identities = 154/913 (16%), Positives = 258/913 (28%), Gaps = 73/913 (7%) Query: 1388 GIAKEDPVQGVANEDAVQGVANEVEVQG---VAHEDAVQGIANEDAAHGIANEVAAHGIA 1444 G + PV G + + G+ +QG + + G+ E G A + + G Sbjct: 540 GFSPGQPVPGEKGDQGLSGLMGPPGMQGDKGLKGHPGLPGLPGEQGIPGFAGNIGSPGYP 599 Query: 1445 NEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAR 1504 QG+A + G G E G E G+ + + Sbjct: 600 GR---QGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIPGIRGKKGFKG------RQ 650 Query: 1505 GIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEV 1564 G + +G A D + G+ G + G + G+ G+ Sbjct: 651 GFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIP---GPMGLSGNK 707 Query: 1565 TAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGI 1624 G+ + QG E ++ A P + K G Sbjct: 708 GLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPP-------------GMRGKSGPSGQ 754 Query: 1625 ANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAV 1684 QG + G + + G + +G+ G ++G E+ Sbjct: 755 TGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPG---PPGLKGTQGEEGP 811 Query: 1685 HGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNE 1744 G E+ G + +G A E +G+ EV QG + G G+T Sbjct: 812 IGAFGELGPRGKPGQ---KGYAGEPGPEGLKGEVGDQGNIGKIGETGPVGLPGEVGMTGS 868 Query: 1745 VAAHGIANEDAAQGIAHEDAVQGIANEDAVHS------VAKEVAAHGVANEDAAHAIAKP 1798 + G G E V G V + V A G Sbjct: 869 IGEKGERGSPGPLGPQGEKGVMGYPGPPGVPGPIGPLGLPGHVGARGPPGSQGPKGQRGS 928 Query: 1799 DAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGI 1858 G+ E QG E G G G + +QG+ +G+ Sbjct: 929 RGPDGLLGEQGIQGAKGEKGDQGKRGPHGLIGKTGNPGERGFQGKPGLQGLPGSTGDRGL 988 Query: 1859 AKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAA 1918 E ++G+ +V G E ++G + G+ E A+G + E Sbjct: 989 PGEPGLRGLQGDVGPPG---EMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGL 1045 Query: 1919 QGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANE 1978 +G +G+ +D +G+ +G+ ED +G G G+ Sbjct: 1046 RGEPGAPGEEGLQGKDGLKGVP---GGRGLPGEDGEKGEMGLPGIIGPLGRSGQTGLPGP 1102 Query: 1979 DAAQGIAHEDAVQGIANEDAVHGVANEDAAHA----IAK--PDAARGIANEVAAQGIATE 2032 + GI + G + G E + I K P ARG V G+ Sbjct: 1103 EGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGLMGP 1162 Query: 2033 DVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEA 2092 D GI G + + P G E + +G Sbjct: 1163 DGEPGIPGYRGHQG---QPGPSGLPGPKGEKGYPGEDSTV------LGPPGPRGEPGPVG 1213 Query: 2093 AQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVAN 2152 Q + A G G+ QG E G G+ E ++G Sbjct: 1214 DQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQG------EQGLKGERGSEGNKG 1267 Query: 2153 EVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQG 2212 + A G + + + G+ QG+ IQG D G ++ G +G Sbjct: 1268 KKGAPGPSGKPGIPGL------QGLLGPKGIQGYHGADGISGNPGKIGPPGKQGLPGIRG 1321 Query: 2213 VANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDA 2272 G +G + G+ + + + QG A G Sbjct: 1322 GPGRTGLAGAPGPPGVKGSSGLPGSPGIQGPKGEQGLPGQPGIQGKRGHRGAQGDQGPCG 1381 Query: 2273 VHGIANEDAVYDI 2285 G+ + Y + Sbjct: 1382 DPGLKGQPGEYGV 1394 Score = 73.6 bits (179), Expect = 2e-12 Identities = 174/1013 (17%), Positives = 282/1013 (27%), Gaps = 132/1013 (13%) Query: 67 GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126 G+ E + G A + + G G G + G A ++ +G Sbjct: 579 GLPGEQGIPGFAGNIGSPGYPGRQGLAGPEGNPGPKGAQGFIGSPGEAGQLGPEGERGIP 638 Query: 127 AVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIA 186 ++G QG + +G A D + G+ G + I Sbjct: 639 GIRGKKGFKGRQGFPGDFGDRGPAGLDGSPGLVGGTGPPGFPGLRGSVGPVGPIGPAGIP 698 Query: 187 NEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQ 246 G+S + GI + QG A E G + G+ ++G + Sbjct: 699 GP---MGLSGNKGLPGIKGDKGEQGTAGELGEPGYPGDKGAVGLPGPPGMRGKSGP---S 752 Query: 247 GVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 306 G + +QG + G ++ G + +G+ G ++G E+ Sbjct: 753 GQTGDPGLQGPSGPPGPEGFPGDIGIPGQNGPEGPKGLLGNRGPPG---PPGLKGTQGEE 809 Query: 307 AVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVA 366 G E+ G + P+ G+ EV QG G Sbjct: 810 GPIGAFGELGPRGKPGQKGYAGEPGPE---GLKGEVGDQGNI---------------GKI 851 Query: 367 KEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAA 426 E G+ E + G + E G + P G+ G+ Sbjct: 852 GETGPVGLPGEVGMTGSIGEKGERG-------SPGPLGPQGEKGVMGYPGPPGVPGPIGP 904 Query: 427 QGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKE 486 G+ V A G +G G+ E QG E QG + Sbjct: 905 LGLPGHVGARGPPGSQGPKGQRGSRGPDGLLGEQGIQGAKGEKGDQG------------K 952 Query: 487 VAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGV 546 HG+ K RG + QG+ G+ E + G+ +V G Sbjct: 953 RGPHGLIGKTGN------PGERGFQGKPGLQGLPGSTGDRGLPGEPGLRGLQGDVGPPG- 1005 Query: 547 ANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAV 606 E+ +G + G+ E A G G E + Sbjct: 1006 --------------------EMGMEGPPGTEGESGLQGEPGAKGDVGTAGSVGGTGEPGL 1045 Query: 607 QGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVA--NEDAAQAI 664 +G G+ +D +G+ G+ ED +G E L G++ + Sbjct: 1046 RGEPGAPGEEGLQGKDGLKGVPG---GRGLPGEDGEKG---EMGLPGIIGPLGRSGQTGL 1099 Query: 665 AKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAA 724 P+ GI + G + G E ++G ++ G +G Sbjct: 1100 PGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGHLGL 1159 Query: 725 QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHE 784 G E + G G + G+ +G ED V +G Sbjct: 1160 MGPDGEPGIPGYRGHQGQPGPS------GLPGPKGEKGYPGEDST--VLGPPGPRGEPGP 1211 Query: 785 DAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGV 844 QG E A G V G+ QG E QG E + G + +G Sbjct: 1212 VGDQGERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGDQG---EQGLKGERGSEGNKGK 1268 Query: 845 AKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIA-NEGVANEVAAQG 903 G +QG++ + + G A GI+ N G QG Sbjct: 1269 KGAPGPSGKPGIPGLQGLLGPKGIQGY-------------HGADGISGNPGKIGPPGKQG 1315 Query: 904 IATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAA 963 + GI +A + G + G+ Sbjct: 1316 LP--------------GIRGGPGRTGLAGAPGPPGVKGSSGLPG------SPGIQGPKGE 1355 Query: 964 QGVANEVAAQGVANEDAV---HGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGI 1020 QG+ + QG G + ++G E VQG+ QG G Sbjct: 1356 QGLPGQPGIQGKRGHRGAQGDQGPCGDPGLKGQPGEYGVQGLT---GFQGFPGPKGPEGD 1412 Query: 1021 ANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG 1073 A V G +G +GI G E +G +G Sbjct: 1413 AGIVGISGPKGPIGHRGNTGPLGREGIIGPTGRTGPRGEKGFRGETGPQGPRG 1465 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 86.7 bits (213), Expect = 3e-16 Identities = 204/1095 (18%), Positives = 292/1095 (26%), Gaps = 88/1095 (8%) Query: 968 NEVAAQGVANEDAVH----GVANEDAVQGVANEVE----VQGIAHKDAIQGIANEDAAHG 1019 +E+ AN+D ++ G E +G +E ++G + G+ G Sbjct: 428 SEIGPGMPANQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPGTMG 487 Query: 1020 IANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDA 1079 +V G G+ D G + + G A A E Sbjct: 488 PTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLM--LPFRFGGGGDAGSKGPMVSAQESQ 545 Query: 1080 AQGIAHED--AVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGV 1137 AQ I + A++G A + G V G ++G + QG G Sbjct: 546 AQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGG---LKGEPGDVGPQGPRGVQGPPGP 602 Query: 1138 AHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAV 1197 A + +G A D A G+ + G D G+ E +G G +D Sbjct: 603 AGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGE 662 Query: 1198 HGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANE 1257 G EV G+ E + P G G+ + G G + Sbjct: 663 RGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQ 722 Query: 1258 VAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQG-IAKEDPVQGVANEDP--I 1314 G QG +G + + G+ D G KE P + P Sbjct: 723 QGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGP 782 Query: 1315 QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKE 1374 QG +GV D ++G+ G ED G + Sbjct: 783 QGPIGYPGPRGVKGADGIRGLKGTKGEKG---------------------EDGFPGFKGD 821 Query: 1375 DAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGI 1434 ++G E G ED +G G + G + V G+ G Sbjct: 822 MGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGP 881 Query: 1435 ANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAA 1494 + G + +G G + G E G+ + G + D Sbjct: 882 KGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGP 941 Query: 1495 HAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIE 1554 A P RG G G +D G + G + G Sbjct: 942 ---AGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGV 998 Query: 1555 DAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHS 1614 QG E G G E L + E G + Sbjct: 999 VGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKE-------------GTKGDPGPAG 1045 Query: 1615 IANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDA 1674 + KD G+ +G+ V A G+ + G G A +G A Sbjct: 1046 LPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPG------PPGPAGSPGERGPAGAAG 1099 Query: 1675 VQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIAN 1734 GI G G E QG A D +QG G+ G Sbjct: 1100 PIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPV------GLPGPAGPVGPPG 1153 Query: 1735 EDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHA 1794 ED G E G + QG QG + E G Sbjct: 1154 EDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKG 1213 Query: 1795 IAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDA 1854 P G V QG+ G P E G ++ G G D Sbjct: 1214 DEGPRGFPGPPGPVGLQGL------PGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADG 1267 Query: 1855 AQGIAKEDPIQGVANEVEVQGVAHEDAV------------QGIANEDAAHGIANEDAAQG 1902 QG G E G A E + +G E G A +G Sbjct: 1268 PQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKG 1327 Query: 1903 IANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVA 1962 +D + G G A QD G +D G + + G E Sbjct: 1328 PPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPG---QTGSPGPTGEPG 1384 Query: 1963 AHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIAN 2022 G + G A + QG G+ G A PD RGI Sbjct: 1385 PSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPG 1444 Query: 2023 EVAAQGIATEDVADG 2037 V QG+ DG Sbjct: 1445 PVGEQGLPGSPGPDG 1459 Score = 75.9 bits (185), Expect = 4e-13 Identities = 190/1062 (17%), Positives = 290/1062 (27%), Gaps = 85/1062 (8%) Query: 1210 ANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAV 1269 A E A AI + A + G+ G G +V G Sbjct: 541 AQESQAQAILQ-QARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGP 599 Query: 1270 QGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHE 1329 G A + +G A D +G+ + +G D + G+ E +G G + Sbjct: 600 PGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGD 659 Query: 1330 DAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGI 1389 D +G E G+ E +G+ G+ + +G G Sbjct: 660 DGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGP 719 Query: 1390 AKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAA 1449 + G QG +G + + G+ D G + G E Sbjct: 720 PGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGK---EGPPGEKGG 776 Query: 1450 QGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANE 1509 QG QG +G+ D + G+ G ED +G E Sbjct: 777 QG---PPGPQGPIGYPGPRGVKGADGIRGLK---GTKGEKGEDGFPGFKGDMGIKGDRGE 830 Query: 1510 VATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGV 1569 + G ED +G +G + G ++ V G+ QG + G Sbjct: 831 IGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGF 890 Query: 1570 ANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDA 1629 + +G + + P G E I K +G + D Sbjct: 891 PGANGEKGGRG-------TPGKPGPRGQRGPTGPRG---ERGPRGITGKPGPKGNSGGDG 940 Query: 1630 AQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAK 1689 G E +G G G +D + G + G Sbjct: 941 PAGPPGERGPNG------------PQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQG 988 Query: 1690 EVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHG 1749 + G QG E G G E + G+A ++ G Sbjct: 989 KTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKG--------- 1039 Query: 1750 IANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVA 1809 + G+ +D G+ + V A G+ + P G A Sbjct: 1040 ---DPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEG------PPGPPGPAGSPG 1090 Query: 1810 AQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVAN 1869 +G A GIP G G E QG A D QG P+ G+ Sbjct: 1091 ERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQG-----PV-GLPG 1144 Query: 1870 EVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQG 1929 G ED +G E G + QG Q + G E +G Sbjct: 1145 PAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRG 1204 Query: 1930 IANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDA 1989 + + G ++ +G G+ QG+ +G + Sbjct: 1205 ------------QQGLFGQKGDEGPRGFPGPPGPVGL------QGLPGPPGEKGETGDVG 1246 Query: 1990 VQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVAN 2049 G G + A P G V +G E G+ E G Sbjct: 1247 QMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKG 1306 Query: 2050 EDAAQAIAKPDAAHGIAN-EGIATEDVADGIAEDA-VQGITNEEAAQAIAKQDAAHGITK 2107 E + + P A G +G +D G G A QD G Sbjct: 1307 ERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKG 1366 Query: 2108 EDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQG 2167 +D G T + G E G + G A + QG E A+G A + G Sbjct: 1367 DDGEPGQTG---SPGPTGEPGPSGPPGKRGPPGPAGPEGRQG---EKGAKGEAGLEGPPG 1420 Query: 2168 VANEVEVQGIAHK---DAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVAN 2224 + QG K D ++GI QG+ G G+ G Sbjct: 1421 KTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKG 1480 Query: 2225 EDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHG 2266 E G+ + G E R + + G E G Sbjct: 1481 EKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITG 1522 Score = 71.2 bits (173), Expect = 1e-11 Identities = 196/1059 (18%), Positives = 277/1059 (26%), Gaps = 83/1059 (7%) Query: 654 VVANEDAAQAIAK--------PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVA 705 V A E AQAI + P G+ G +G + QG Sbjct: 539 VSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQG 598 Query: 706 AHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVAN 765 G + + +G A D A+G+ + +G D + G+ E G G Sbjct: 599 PPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPG 658 Query: 766 EDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQG 825 +D +G EV +G+ E +G+ G GV D G QG Sbjct: 659 DDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPG---PPGPPGVTGMDGQPGPKGNVGPQG 715 Query: 826 VANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPD 885 E G AQG+ A G E +G + + L G+ + P Sbjct: 716 ---EPGPPGQQGNPGAQGLPGPQGAIGPPGE---KGPLGKPGLPGMPGADG-------PP 762 Query: 886 AAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAA 945 G EG E QG I G+ A I Sbjct: 763 GHPG--KEGPPGEKGGQG--PPGPQGPIGYPGPRGVK------------GADGIRGLKGT 806 Query: 946 QGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHK 1005 +G ED G + +G E+ G ED G G + G K Sbjct: 807 KGEKGEDGFPGFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGK 866 Query: 1006 DAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGI 1065 + G+ G + G + +G G + G E +GI Sbjct: 867 LGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGI 926 Query: 1066 ANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAV 1125 + +G + D G E G G G G E Sbjct: 927 TGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGF 986 Query: 1126 QGVANE------VEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAA 1179 QG V QG E G G E G+A ++ +G + Sbjct: 987 QGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKG---DPGP 1043 Query: 1180 QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATE 1239 G+ +D G+ G+ V A G+ + P G A +G A Sbjct: 1044 AGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEG------PPGPPGPAGSPGERGPAGA 1097 Query: 1240 DVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGI 1299 GI G G E QG A D QG G+ G Sbjct: 1098 AGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPV------GLPGPAGPVGP 1151 Query: 1300 AKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAA 1359 ED +G E +G + QG QG + G E +G Sbjct: 1152 PGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRG------- 1204 Query: 1360 QDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHE 1419 QG+ + +G G + G E G ++ G Sbjct: 1205 --------QQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGP 1256 Query: 1420 DAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIA---HEDAVQGIANEDAV 1476 G D G + G E G A E G +G E Sbjct: 1257 RGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGP 1316 Query: 1477 HGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANE 1536 G A G +D P G G A +D G +D G Sbjct: 1317 SGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGS 1376 Query: 1537 VAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQA 1596 G G G G E ++G + A Sbjct: 1377 PGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTG----PIGPQGAPG 1432 Query: 1597 IAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDA 1656 PD GI V + G G+ G E G+ Sbjct: 1433 KPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIG 1492 Query: 1657 AQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHG 1695 G E +G+ G E + G + + G Sbjct: 1493 PPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPG 1531 Score = 69.7 bits (169), Expect = 3e-11 Identities = 197/1070 (18%), Positives = 288/1070 (26%), Gaps = 100/1070 (9%) Query: 692 ANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAA 751 A E AQ I + A + G+ G ++G + G Sbjct: 541 AQESQAQAILQQ-ARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGP 599 Query: 752 HGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANE 811 G A + +G A D +G+ + +G D + G+ E G G + Sbjct: 600 PGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGPPGD 659 Query: 812 DAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGV 871 D +G E +G+ E G+ G G+ + +G V + G Sbjct: 660 DGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGP 719 Query: 872 VANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGI-AKDAAHGITKEEAAQAI 930 + A P I G + G+ ADG G E+ Q Sbjct: 720 PGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQG- 778 Query: 931 AKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAV 990 QG GV D +G+ +G ED G + + Sbjct: 779 -----------PPGPQGPIGYPGPRGVKGADGIRGLKG---TKGEKGEDGFPGFKGDMGI 824 Query: 991 QGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANE 1050 +G E+ G +D +G +G + G + G+ QG Sbjct: 825 KGDRGEIGPPGPRGEDGPEGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGS 884 Query: 1051 VAAHGISKEDAVQG---------IANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1101 + G + +G + G E +GI + +G + D G Sbjct: 885 IGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGP 944 Query: 1102 AKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAA 1161 E +G G G G E QG G+ V Sbjct: 945 PGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGV---VGP 1001 Query: 1162 HGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKP 1221 G E G G E + G+A ++ G + G+ +D + Sbjct: 1002 QGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKG---DPGPAGLPGKDGPPGLRGF 1058 Query: 1222 DAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGI 1281 RG+ V A G+ + G + G A G GI QG Sbjct: 1059 PGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAGAAGPI------GIPGRPGPQGP 1112 Query: 1282 AKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAA 1341 +G E QG A D +QG + G A V G ED +G E Sbjct: 1113 PGPAGEKGAPGEKGPQGPAGRDGLQGPVG---LPGPAGPVGPPG---EDGDKGEIGEPGQ 1166 Query: 1342 HGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANE 1401 G + QG Q + G E +G QG+ + +G Sbjct: 1167 KGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGPRG------QQGLFGQ---KGDEGP 1217 Query: 1402 DAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGI 1461 G V +QG+ G E G ++ G G D QG Sbjct: 1218 RGFPGPPGPVGLQGLP------GPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQG- 1270 Query: 1462 AHEDAVQGIANEDAV--HGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATED 1519 GI N AV G E G+ E P RG E G A Sbjct: 1271 ----PPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPG---PKGERGEKGESGPSGAAGPP 1323 Query: 1520 VADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVV 1579 G +D G V G G A +D G +D G Sbjct: 1324 GPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGD---------KGDDGEPGQT 1374 Query: 1580 NEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAA 1639 G E K G A + QG Sbjct: 1375 GSP----------------------GPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGE 1412 Query: 1640 HGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANE 1699 G+ G A G D +GI QG+ G + G+ Sbjct: 1413 AGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGL 1472 Query: 1700 DPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHG 1749 G E G+ + G E +G+ + G E G Sbjct: 1473 KGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITG 1522 Score = 62.4 bits (150), Expect = 5e-09 Identities = 178/1027 (17%), Positives = 268/1027 (26%), Gaps = 89/1027 (8%) Query: 67 GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126 G ++G +V QG G A + G A D A+G+ + +G D Sbjct: 574 GPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFD 633 Query: 127 AVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIA 186 + G+ E +G G +D G E +G+ E + + Sbjct: 634 GLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPP 693 Query: 187 NEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQ 246 G+ + +G G + G QG +G + + Sbjct: 694 GPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLP 753 Query: 247 GVAHEDAVQGIANEDAAHGITN---------EVAAHGIANEDAAQGIANEDAAQGIAHED 297 G+ D G ++ G + G A GI +G ED Sbjct: 754 GMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGED 813 Query: 298 AVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIA 357 G + + G E+ G ED P+ G G G Sbjct: 814 GFPGFKGDMGIKGDRGEIGPPGPRGEDG------PEGPKGRGGPNGDPGPL------GPP 861 Query: 358 NEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAA 417 E GV G +G + G + KP G + Sbjct: 862 GEKGKLGVP---GLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKP----GPRGQRGP 914 Query: 418 HGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANE 477 G E +GI + G S D G E G G G + Sbjct: 915 TGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNG---PQGPTGFPGPKGPPGPPGK 971 Query: 478 DAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGV 537 D + G + G K +G E G G E + G+ Sbjct: 972 DGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGL 1031 Query: 538 ANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAV 597 A + G + + D G+ +G+ A G+ + G Sbjct: 1032 AGK---EGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPP----- 1083 Query: 598 HGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVAN 657 G A +G A G+ QG G E QG D L G V Sbjct: 1084 -GPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGL 1142 Query: 658 EDAAQAIAKP--DAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAV 715 A + P D G E G + QG QG + G E Sbjct: 1143 PGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGP 1202 Query: 716 QGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANE 775 +G QG+ + G G + G E G + Sbjct: 1203 RG---------------QQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQ 1247 Query: 776 VEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGV 835 + G G D G + G E G A E G G Sbjct: 1248 MGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGE 1307 Query: 836 ANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGV 895 E G + G +G ++ G + + P G Sbjct: 1308 RGEKGESGPS------GAAGPPGPKGPPGDDGPKG------SPGPVGFPGDPGPPGEPGP 1355 Query: 896 ANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAH 955 A + G +D G + + G T E + + QG E A Sbjct: 1356 AGQDGPPGDKGDDGEPG--QTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQG---EKGAK 1410 Query: 956 GVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANED 1015 G A + G + QG G D ++G+ V QG + G D Sbjct: 1411 GEAGLEGPPGKTGPIGPQGAP------GKPGPDGLRGIPGPVGEQG------LPGSPGPD 1458 Query: 1016 AAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIA 1075 G G+ + +G E G+ + G E +G+ + G Sbjct: 1459 GPPGPMGPPGLPGLKGDSGPKG---EKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPK 1515 Query: 1076 NEDAAQG 1082 E G Sbjct: 1516 GEQGITG 1522 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 84.7 bits (208), Expect = 1e-15 Identities = 193/1085 (17%), Positives = 287/1085 (26%), Gaps = 100/1085 (9%) Query: 112 GVANEVAAQGVANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANED 171 G A +QG E +G QG+ E V G G + G++ Sbjct: 132 GPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPF 191 Query: 172 AAQDIAKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVA 231 +AQ +A D G+ + + + G QG+ + G Sbjct: 192 SAQ----------MAGLDEKSGLGSQVGLM-----PGSVGPVGPRGPQGLQGQQGGAGPT 236 Query: 232 NEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQ 291 G + G + G ED G G A A+G Sbjct: 237 GPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLP 296 Query: 292 GIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATED 351 G+ +G + G EV A G E A P G + +G+ E Sbjct: 297 GL------KGHRGHKGLEGPKGEVGAPGSKGE------AGPTGPMGAMGPLGPRGMPGER 344 Query: 352 VADGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGI 411 G G AHG+ + G + G N Sbjct: 345 GRLGPQGAPGQRG------AHGMPGKPGPMGPLGIPGSSGFPGNP--------------- 383 Query: 412 ANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAV 471 G+ E G + QG E G G D Sbjct: 384 ----------------GMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGT 427 Query: 472 QGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANE 531 G G + + G P RG + G E G E Sbjct: 428 PGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEA---GPKGE 484 Query: 532 DAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGV 591 HG+ + G + G E G +DG+ A G Sbjct: 485 PGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGE 544 Query: 592 ANEVAVHGVAIEDAVQGVANEDAV---HGVANEDAAQGIAKEVTAHGVANEDAVQGVVNE 648 V G G E + G+ QG ++ G ED G Sbjct: 545 RGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGS 604 Query: 649 DALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHG 708 + G + + + P + G + G A +G +D G + V G Sbjct: 605 IGIRG----QPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPG 660 Query: 709 ISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE---VAAHGVANEDPVQGVAN 765 ++ E QG QG+ G + GV + V G E G Sbjct: 661 LAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERG 720 Query: 766 EDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQG 825 E + G+ E + G D +G G G+ E G +G Sbjct: 721 EPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRG 780 Query: 826 VANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPD 885 E G A D A+G+ + G +G L G P Sbjct: 781 GIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVG------------PPG 828 Query: 886 AAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAA 945 + + G A G A DG G+ K E + K DA Sbjct: 829 SRGNPGSRGENGPTGAVGFAGPQGPDG-----QPGV-KGEPGEPGQKGDAG-----SPGP 877 Query: 946 QGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHK 1005 QG+A HG +G G G G G K Sbjct: 878 QGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGK 937 Query: 1006 DAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGI 1065 + G+ + +HG + G +G ED G G + + + G+ Sbjct: 938 EGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGM 997 Query: 1066 ANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAV 1125 + +G+ G + G + G ++G E +G A D Sbjct: 998 PGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGT 1057 Query: 1126 QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHE 1185 G V +G + G+ A G V A G A + G G A + Sbjct: 1058 PGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGK 1117 Query: 1186 DAVQG 1190 + G Sbjct: 1118 RGLPG 1122 Score = 82.8 bits (203), Expect = 4e-15 Identities = 201/1131 (17%), Positives = 298/1131 (26%), Gaps = 51/1131 (4%) Query: 1118 GVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANED 1177 G A QG E +G QGI E G G + G++ Sbjct: 132 GPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPF 191 Query: 1178 AAQGIAHEDAVQGIANE-DAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGI 1236 +AQ +A D G+ ++ + G V G A P G + G Sbjct: 192 SAQ-MAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGP 250 Query: 1237 ATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAA 1296 G + G E G + G A A+G + G+ Sbjct: 251 I------GSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGH 304 Query: 1297 QGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANE 1356 +G+ G G + G + G G + A G+ + Sbjct: 305 KGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGK 364 Query: 1357 DAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGV 1416 + G ++G A A+G E P QG E G + G Sbjct: 365 PGPMGPLGIPGSSGFPGNPGMKGEAGPTGARG--PEGP-QGQRGETGPPGPVGSPGLPGA 421 Query: 1417 AHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAV 1476 D G + G + + G QG +G + V G E Sbjct: 422 IGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGP 481 Query: 1477 HGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANE 1536 G E HG+ RG V G E A G + G+ Sbjct: 482 KG---EPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGP 538 Query: 1537 VAAQGIANEVAVHGVAIEDAVQGVVKEVT---AHGVANEDAVQGVVNEDALHSVVA-NED 1592 AQG V G G E A G+ VQG E L + A ED Sbjct: 539 KGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGP--EGKLGPLGAPGED 596 Query: 1593 AAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIA 1652 P + GI + + + + G + G A G +D G + Sbjct: 597 GRPG---PPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPS 653 Query: 1653 NEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQ 1712 G+A E QG QG+ G + GV + G + Sbjct: 654 GPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGER 713 Query: 1713 GVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANED 1772 G E G+ +G+A G G + G+ QG+ E Sbjct: 714 GNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGL------QGMPGER 767 Query: 1773 AVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVA 1832 + G E A A D ARG+ + G A G P G Sbjct: 768 GIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPP 827 Query: 1833 NEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAH 1892 G E+ G QG + ++G E +G A QG+A H Sbjct: 828 GSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPH 887 Query: 1893 GIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANED 1952 G +G + G G G ++ G+ + Sbjct: 888 GPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDP 947 Query: 1953 AAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIA 2012 + G + G +G ED G G + + G+ + + Sbjct: 948 GSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMP 1007 Query: 2013 KPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIAT 2072 G +V G + G ++G E + A N+G Sbjct: 1008 GLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPA--------GNDGTPG 1059 Query: 2073 EDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGV 2132 D A G D G+ A G V A G A + G Sbjct: 1060 RDGAVGERGD--------------RGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGS 1105 Query: 2133 ANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAA 2192 + G A + G +G + +G G+ G E + Sbjct: 1106 RGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGS 1165 Query: 2193 QGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANE 2243 G+ G G G +G E G E Sbjct: 1166 AGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGE 1216 Score = 80.9 bits (198), Expect = 1e-14 Identities = 169/952 (17%), Positives = 262/952 (27%), Gaps = 49/952 (5%) Query: 1306 QGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANE 1365 QG E +G QG+ E V G G + G++ +AQ +A Sbjct: 140 QGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQ-MAGL 198 Query: 1366 DAAQGISKEDAVQ----GIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDA 1421 D G+ + + G QG+ + G G + G + Sbjct: 199 DEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEG 258 Query: 1422 VQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAK 1481 G ED G G A A+G G+ +G + G Sbjct: 259 PPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGL------KGHRGHKGLEGPKG 312 Query: 1482 EVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVA---DGIANEDAAHGVANEVA 1538 EV A G E A P G + +G+ E G + AHG+ + Sbjct: 313 EVGAPGSKGE------AGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPG 366 Query: 1539 AQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIA 1598 G + + G + G+ E G + QG E V + AI Sbjct: 367 PMG---PLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIG 423 Query: 1599 KPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQ 1658 D G + + + G QG G + V G E + Sbjct: 424 T-DGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPK 482 Query: 1659 GIANEDAAQGIAH---EDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVA 1715 G QG E+ +G + G V G +G D + G Sbjct: 483 GEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGN---RGFPGSDGLPGPK 539 Query: 1716 NEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVH 1775 +G +G + G A G+ QG + G ED Sbjct: 540 GAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRP 599 Query: 1776 SVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEV 1835 + G+ + + + P + G + G A G P +D G + V Sbjct: 600 GPPGSI---GIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPV 656 Query: 1836 AAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIA 1895 G++ E QG QG+ G + QGV + G G Sbjct: 657 GPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNP 716 Query: 1896 NEDAAQGIANEDAAQDIAN---EDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANED 1952 E GI + +A D +G G QG+ E + G Sbjct: 717 GERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPK 776 Query: 1953 AAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIA 2012 +G E A G A D A+G+ G A +G + G Sbjct: 777 GDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSR 836 Query: 2013 KPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIAT 2072 + G QG + G E G A Q +A HG Sbjct: 837 GENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHG-------- 888 Query: 2073 EDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGV 2132 +G+ ++G + + G G G ++ G+ Sbjct: 889 ---PNGVP--GLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGL 943 Query: 2133 ANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAA 2192 + +HG + G +G ED G G + I G+ + Sbjct: 944 RGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGE 1003 Query: 2193 QGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANED 2244 +G+ G + G + G + G E G A D Sbjct: 1004 RGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGND 1055 Score = 79.3 bits (194), Expect = 4e-14 Identities = 142/797 (17%), Positives = 215/797 (26%), Gaps = 41/797 (5%) Query: 65 AHGITNEDAVQGVANEVAAQGVANEDAAHGVANE------VAAHGVANEDAAQGVANEVA 118 A G + G + QG + AHG+ + + G + G+ E Sbjct: 331 AMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAG 390 Query: 119 AQGVANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAK 178 G + QG E G + G D G + G + + Sbjct: 391 PTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPG 450 Query: 179 EDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQG 238 Q +G + V G E +G +QG +G G Sbjct: 451 SPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPG 510 Query: 239 VANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDA 298 G +G D G G +G + G Sbjct: 511 TVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPG 570 Query: 299 VQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIAN 358 +G+ V G ++ G ED P + GI + + G+ + G Sbjct: 571 ARGLTGNPGVQGPEGKLGPLGAPGEDGRPG---PPGSIGIRGQPGSMGLPGPKGSSGDPG 627 Query: 359 EDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAH 418 + G A G +D G G +A E Q P G+ Sbjct: 628 KPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPG-LAGERGEQGPPGPTGFQGLPGPPGPP 686 Query: 419 GIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANED 478 G + QG+ + A G +G E GI +G+A G Sbjct: 687 GEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSP 746 Query: 479 AVHGVAKEVAAHGVANKDAAHAIA---KPDAARGIANEVAAQGIATEDVADGIANEDAVH 535 G + G+ IA P RG E A+G A D A G+ Sbjct: 747 GPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPP 806 Query: 536 GVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEV 595 G A G E + P + G G E+ G Sbjct: 807 GPAGPTGEKG---EPGPRGLVGPPGSRG---------------NPGSRGENGPTGAVGFA 848 Query: 596 AVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVV 655 G + V+G E G A QG+A HG ++G G Sbjct: 849 GPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGAT 908 Query: 656 ANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAV 715 +A + P A G G ++ G+ + + G + G Sbjct: 909 GFPGSAGRVGPPGPA-GAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGD 967 Query: 716 QGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANE 775 +G ED G D G A G+ G+ + +G+ G + Sbjct: 968 KGDPGEDGQPG---PDGPPGPAGTTGQRGIV------GMPGQRGERGMPGLPGPAGTPGK 1018 Query: 776 VEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGV 835 V G + G ++G E G A D G +G + G+ Sbjct: 1019 VGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGL 1078 Query: 836 ANEDAAQGVAKEVTAHG 852 A G V A G Sbjct: 1079 PGSQGAPGTPGPVGAPG 1095 Score = 78.6 bits (192), Expect = 7e-14 Identities = 169/976 (17%), Positives = 249/976 (25%), Gaps = 19/976 (1%) Query: 581 GIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANED 640 G A + G E G QG+ E V G G G++ Sbjct: 132 GPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPF 191 Query: 641 AVQ--GVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQ 698 + Q G+ + L V + P G+ + G G Sbjct: 192 SAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPI 251 Query: 699 GIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANED 758 G G ED G G A +G + G+ G+ Sbjct: 252 GSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPK 311 Query: 759 PVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVA 818 G G + G + G G + AHG+ + G Sbjct: 312 GEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPL 371 Query: 819 NEDAAQGVANEDAVHGVANEDAA------QGVAKEVTAHGVTNEDAVQGVVNEEALHGVV 872 + G + G A A QG E G + G + + G Sbjct: 372 GIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAK 431 Query: 873 ANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAK 932 + P +A + G QGI + G+ G E + Sbjct: 432 GPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVP-----GFKGEAGPKG--- 483 Query: 933 QDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQG 992 + H I G + G G E A G G+ QG Sbjct: 484 EPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQG 543 Query: 993 VANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVA 1052 V G G E G G+ + G G Sbjct: 544 ERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPG 603 Query: 1053 AHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVAN 1112 + GI + G+ + G + G A +G +D G + V G+A Sbjct: 604 SIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAG 663 Query: 1113 EDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQG 1172 E QG QG+ G + QG+ + A G G E G Sbjct: 664 ERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPG 723 Query: 1173 IANEDAAQGIA---HEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIAN 1229 I +G+A D +G G G+ E P RG Sbjct: 724 ITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIG 783 Query: 1230 EVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQG 1289 E A+G A D A G+ G A G + G G E+ G Sbjct: 784 EKGAEGTAGNDGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTG 843 Query: 1290 IANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDA 1349 QG + V+G E +G A QG+A G G Sbjct: 844 AVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQG 903 Query: 1350 AQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVAN 1409 G + G G ++ G+ + G + G Sbjct: 904 PPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPG 963 Query: 1410 EVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQG 1469 +G ED G G + G+ + +G+ G + G Sbjct: 964 GPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTG 1023 Query: 1470 IANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDA 1529 + G ++G E A D G V +G + G+ Sbjct: 1024 ATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQG 1083 Query: 1530 AHGVANEVAAQGIANE 1545 A G V A G A + Sbjct: 1084 APGTPGPVGAPGDAGQ 1099 Score = 71.2 bits (173), Expect = 1e-11 Identities = 123/669 (18%), Positives = 175/669 (26%), Gaps = 44/669 (6%) Query: 1605 GIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANED 1664 G + AH + K G + G G+ E G + QG E Sbjct: 351 GAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNP---GMKGEAGPTGARGPEGPQGQRGET 407 Query: 1665 AAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVA 1724 G + G D G + G + G QG ++G Sbjct: 408 GPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQP 467 Query: 1725 HEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAH 1784 + V G E G E HGI G + +G E A Sbjct: 468 GDPGVPGFKGEAGPKG---EPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAP 524 Query: 1785 GVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKED 1844 G + + P A+G V + G G P E G A G++ Sbjct: 525 GNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPG------ARGLTGNP 578 Query: 1845 AVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIA 1904 VQG + G ED G + ++G + G+ + G + G A Sbjct: 579 GVQGPEGKLGPLGAPGEDGRPGPPGSIGIRG---QPGSMGLPGPKGSSGDPGKPGEAGNA 635 Query: 1905 NEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAH 1964 + +D G S G+A + QG QG+ G + Sbjct: 636 GVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQ 695 Query: 1965 GIANEDAAQGIAN---EDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIA 2021 G+ + A G E G E + G+ E + G D P G Sbjct: 696 GVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDT 755 Query: 2022 NEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANE----------GIA 2071 QG+ E G G E A+ A D A G+ G Sbjct: 756 GPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEK 815 Query: 2072 TEDVADGIA-------------EDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEV 2118 E G+ E+ G Q Q G E +G Sbjct: 816 GEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSP 875 Query: 2119 AAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIA 2178 QG+A HG G G + G G G Sbjct: 876 GPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEP 935 Query: 2179 HKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVH 2238 K+ G+ + + G V G A G + G D G A Sbjct: 936 GKEGPPGLRGDPGSHG---RVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQR 992 Query: 2239 GVANEDAAR 2247 G+ R Sbjct: 993 GIVGMPGQR 1001 Score = 62.8 bits (151), Expect = 4e-09 Identities = 131/686 (19%), Positives = 190/686 (27%), Gaps = 54/686 (7%) Query: 1616 ANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAV 1675 A +QG + +G GI E V G G + G++ + Sbjct: 134 AGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSA 193 Query: 1676 QGIANEDAVHGVAKEVAA-------------HGVANEDPVQGVANEDAVQGVANEVEVQG 1722 Q +A D G+ +V G+ + G G + G Sbjct: 194 Q-MAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIG 252 Query: 1723 VAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANE---DAVHSVAK 1779 + G ED G G A A+G + G+ + Sbjct: 253 SRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKG 312 Query: 1780 EVAAHGVANE---DAAHAIAKPDAARGIANE---VAAQGIATEDVADGIPNEDAAHGVAN 1833 EV A G E P RG+ E + QG + A G+P + G Sbjct: 313 EVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLG 372 Query: 1834 EVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHG 1893 + G ++G A A+G E P QG E G + G D G Sbjct: 373 IPGSSGFPGNPGMKGEAGPTGARG--PEGP-QGQRGETGPPGPVGSPGLPGAIGTDGTPG 429 Query: 1894 IANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDA 1953 + G + + QG + QGI Q G V G E Sbjct: 430 AKGPTGSPGTSGPPGSAGPPGSPGPQGST---GPQGIRGQPGDPG------VPGFKGEAG 480 Query: 1954 AQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAK 2013 +G E HGI G + +G G E G + + Sbjct: 481 PKG---EPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPG 537 Query: 2014 PDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATE 2073 P A+G V + G G E G + P+ G G E Sbjct: 538 PKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPL--GAPGE 595 Query: 2074 DVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVA 2133 D G GI + + + + G + G +G +D G + Sbjct: 596 DGRPGPPGSI--GIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPS 653 Query: 2134 NEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAI---------- 2183 V G+A E QG QG+ G + QG+ Sbjct: 654 GPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGER 713 Query: 2184 --QGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVA 2241 G E G+ E G D +G G QG+ E + G Sbjct: 714 GNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTP 773 Query: 2242 NEDAARHMAKEDAAQGIANEDAAHGI 2267 R E A+G A D A G+ Sbjct: 774 GPKGDRGGIGEKGAEGTAGNDGARGL 799 Score = 61.6 bits (148), Expect = 9e-09 Identities = 117/654 (17%), Positives = 174/654 (26%), Gaps = 45/654 (6%) Query: 1623 GIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 1682 G A A+G G+ +G+ G G G Sbjct: 279 GFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPR 338 Query: 1683 AVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIT 1742 + G + G + G+ + G G ++G A A G Sbjct: 339 GMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPE 398 Query: 1743 NEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAAR 1802 G E G + G D + G + + A P + Sbjct: 399 GPQGQRG---ETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGS---AGPPGSP 452 Query: 1803 GIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKED 1862 G QGI + G+P G E HGI G E+ +G + Sbjct: 453 GPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPG---EEGKRGPRGDP 509 Query: 1863 PIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGIS 1922 G V +G G G E G + +Q G+ Sbjct: 510 GTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLP 569 Query: 1923 KEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQ 1982 +G+ QG + G ED G + GI + + G+ + Sbjct: 570 ---GARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSI---GIRGQPGSMGLPGPKGSS 623 Query: 1983 GIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANED 2042 G + G A G +D + P G+A E QG G+ Sbjct: 624 GDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPP 683 Query: 2043 AAHGVANEDAAQAI-AKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQDA 2101 G + Q + P A + G G E + G+ E+ D Sbjct: 684 GPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERG--EPGITGLPGEKGMAGGHGPDG 741 Query: 2102 AHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVAN 2161 G G T QG+ E G+A G +G E A+G A Sbjct: 742 PKGSPGPSGTPGDTGPPGLQGMPGE---RGIA------GTPGPKGDRGGIGEKGAEGTAG 792 Query: 2162 EDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQG 2221 D +G+ + G A +G E +G+ + G G V G Sbjct: 793 NDGARGLPGPLGPPGPAGPTGEKG---EPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAG 849 Query: 2222 VANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVHG 2275 D GV E E +G A G+A HG Sbjct: 850 PQGPDGQPGVKGEPG---------------EPGQKGDAGSPGPQGLAGSPGPHG 888 Score = 60.1 bits (144), Expect = 3e-08 Identities = 141/778 (18%), Positives = 208/778 (26%), Gaps = 71/778 (9%) Query: 75 QGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANE 134 +G V G E A G + G+ AQG V + G G E Sbjct: 506 RGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGE 565 Query: 135 DAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQGI 194 + G G+ + G G + I + + + + G Sbjct: 566 PGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGD 625 Query: 195 SKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAV 254 + G A +G +D G + G+A E QG QG+ Sbjct: 626 PGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGP 685 Query: 255 QGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE 314 G + G+ + A G +G E GI +G+A G Sbjct: 686 PGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGS 745 Query: 315 VAAHGVANEDAAHAIAKPDAAHGIANEVATQGI---ATEDVADGIANEDAAHGVAKEVTA 371 G + + GIA +G E A+G A D A G+ + Sbjct: 746 PGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGP 805 Query: 372 HGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIAN 431 G A +G E + + P + G + G A G A Sbjct: 806 PGPAGPTGEKG-------------EPGPRGLVGPPGSRG---NPGSRGENGPTGAVGFAG 849 Query: 432 EVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHG 491 QG + +G E +G A QG+A HG +G Sbjct: 850 P------------QGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHG------PNG 891 Query: 492 VANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIA------NEDAVHGVANEVAAHG 545 V P A G G A G A ++ G+ + +HG Sbjct: 892 VPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHG 951 Query: 546 VANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDA 605 + G A G + DG D G A G+ Sbjct: 952 RVGD------------RGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIV---- 995 Query: 606 VQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIA 665 G+ + G+ G +V G + G V +G V E + A Sbjct: 996 --GMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPV-GEPGPEGPA 1052 Query: 666 KPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQ 725 D G V G + G+ A G V A G + + G Sbjct: 1053 GNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPP 1112 Query: 726 GIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHED 785 G A + + G G + HG + +G +QG+ G E Sbjct: 1113 GRAGKRGLPG------PQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNG---EQ 1163 Query: 786 AVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQG 843 GI G V G G +G E G E G Sbjct: 1164 GSAGIPGPFGPRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPG 1221 Score = 56.6 bits (135), Expect = 3e-07 Identities = 107/558 (19%), Positives = 149/558 (26%), Gaps = 22/558 (3%) Query: 57 IANEDADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANE 116 + A G D + G +G G + G A+G+ Sbjct: 518 VGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGN 577 Query: 117 VAAQGVANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDI 176 QG + G ED G ++G + + G+ + G + Sbjct: 578 PGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRG---QPGSMGLPGPKGSSGDPGKPGEAGN 634 Query: 177 AKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAV 236 A + +D G S G+A E QG QG+ G + Sbjct: 635 AGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGD 694 Query: 237 QGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIA---NEDAAQGIANEDAAQGI 293 QGV + G +G E GIT G+A D +G G Sbjct: 695 QGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSGTPGD 754 Query: 294 AHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVA 353 +QG+ E + G G E A A D A G+ + G A Sbjct: 755 TGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPA----- 809 Query: 354 DGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIAN 413 G E G V G +G E+ G V +P G Sbjct: 810 -GPTGEKGEPGPRGLVGPPGSRGNPGSRG---ENGPTGAVGFAGPQGPDGQP-GVKGEPG 864 Query: 414 EVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQG 473 E G A QG+A HG + V G+ QG G A G Sbjct: 865 EPGQKGDAGSPGPQGLAGSPGPHG---PNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPG 921 Query: 474 IANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDA 533 A G E G RG A G + DG D Sbjct: 922 PAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDG 981 Query: 534 VHGVANEVAAHGVA---NEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHG 590 G A G+ + + G +V G + G ++G Sbjct: 982 PPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNG 1041 Query: 591 VANEVAVHGVAIEDAVQG 608 E G A D G Sbjct: 1042 PVGEPGPEGPAGNDGTPG 1059 Score = 53.9 bits (128), Expect = 2e-06 Identities = 87/474 (18%), Positives = 126/474 (26%), Gaps = 16/474 (3%) Query: 56 DIANEDADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVAN 115 + N G +D G + V G+A E G G+ G Sbjct: 631 EAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGG 690 Query: 116 EVAAQGVANEDAV---QGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDA 172 + QGV + G E G E + G+ E G D +G Sbjct: 691 KPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKGSPGPSG 750 Query: 173 AQDIAKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVAN 232 Q + E G +G E A+G A D +G+ G A Sbjct: 751 TPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAG 810 Query: 233 EDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQG 292 +G + G G E+ G G + +G E +G Sbjct: 811 PTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKG 870 Query: 293 IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDV 352 A QG+A HG +GV P A G G Sbjct: 871 DAGSPGPQGLAGSPGPHG------PNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAG 924 Query: 353 ADGIA------NEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPD 406 A G A ++ G+ + +HG + G G ED P Sbjct: 925 APGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKG-DPGEDGQPGPDGPP 983 Query: 407 AAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIA 466 G + G+ + +G+ G + G + G + G Sbjct: 984 GPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPV 1043 Query: 467 HEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIA 520 E +G A D G V G + A G V A G A Sbjct: 1044 GEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDA 1097 Score = 35.8 bits (81), Expect = 0.52 Identities = 59/315 (18%), Positives = 85/315 (26%), Gaps = 9/315 (2%) Query: 63 DAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGV 122 D A G+ G A +G G G E+ G QG Sbjct: 794 DGARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGP 853 Query: 123 ANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAA 182 + V+G E +G A QG+A HG G+ + A Sbjct: 854 DGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHG------PNGVPGLKGGRGTQGPPGA 907 Query: 183 QDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANE 242 G G A G KE P G+ + G + G Sbjct: 908 TGFPGSAGRVGPPGPAGAPGPAGPLGEPG--KEGP-PGLRGDPGSHGRVGDRGPAGPPGG 964 Query: 243 VEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGI 302 +G ED G G T + G+ + +G+ G + G Sbjct: 965 PGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGA 1024 Query: 303 ANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAA 362 + G ++G E A D G V +G + G+ A Sbjct: 1025 TGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGA 1084 Query: 363 HGVAKEVTAHGVANE 377 G V A G A + Sbjct: 1085 PGTPGPVGAPGDAGQ 1099 >gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] Length = 1745 Score = 83.2 bits (204), Expect = 3e-15 Identities = 163/918 (17%), Positives = 243/918 (26%), Gaps = 49/918 (5%) Query: 1118 GVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANED 1177 G+ G+ ++G + QG HG V G D A+G+ + Sbjct: 485 GLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDT 544 Query: 1178 AAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIA 1237 +G D + G+ E G V G ED P G A E +G+ Sbjct: 545 GPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLL 604 Query: 1238 TEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQ 1297 + G G+ A G G + G QG+ + Sbjct: 605 GPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEK 664 Query: 1298 GIAKEDPVQGVANED-PI-----QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQ 1351 G + G+ D P+ +G E QG G G + Q Sbjct: 665 GPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQ 724 Query: 1352 GIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEV 1411 G E ED G + ++G + A G ED +G + G Sbjct: 725 GEKGE------KGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPP 778 Query: 1412 EVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIA 1471 G + V G+ G + G +G + + G+ E G Sbjct: 779 GSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSR 838 Query: 1472 NEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAH 1531 E G + G +D A I +G+ G G +D Sbjct: 839 GERGQPGATGQPGPKGDVGQDGAPGI---PGEKGLPGLQGPPGFPGPKGPPGHQGKDGRP 895 Query: 1532 GVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANE 1591 G + G + G A QG EV G G E L + E Sbjct: 896 GHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGRE 955 Query: 1592 DAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGI 1651 A + P G G +G G + +G Sbjct: 956 GAKGELGPPGPL-GKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGP 1014 Query: 1652 ANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAV 1711 G+ + ++G +G E G + G G A Sbjct: 1015 LGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGE 1074 Query: 1712 QGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANE 1771 +G +V G +G A GI G D AQG + G + Sbjct: 1075 EGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGD 1134 Query: 1772 DAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGV 1831 D V GV + P +G +V + G HG Sbjct: 1135 DGVRGFV------GVIGPPGLQGLPGPPGEKGEVGDVGSMG---------------PHGA 1173 Query: 1832 ANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAA 1891 G + + G+ G E +G A + G GI Sbjct: 1174 PGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPG------APGIPGPKGD 1227 Query: 1892 HGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANE 1951 G + G A + ED A+G + G G + V GI Sbjct: 1228 IGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPG------DLGPPGDPGVSGIDGS 1281 Query: 1952 DAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAI 2011 +G +V G G +G + +G E G D Sbjct: 1282 PGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGR 1341 Query: 2012 AKPDAARGIANEVAAQGI 2029 P ARG V +G+ Sbjct: 1342 TGPMGARGPPGRVGPEGL 1359 Score = 82.4 bits (202), Expect = 5e-15 Identities = 158/903 (17%), Positives = 242/903 (26%), Gaps = 41/903 (4%) Query: 667 PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG 726 P G+ G+ +G + QG HG G D A+G Sbjct: 480 PPGPVGLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARG 539 Query: 727 IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDA 786 + + +G D + G+ E G G ED +G G A E Sbjct: 540 LPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPG 599 Query: 787 VQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAK 846 +G+ + G G+ A+G G + HG QG+ Sbjct: 600 PRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIG 659 Query: 847 EVTAHGVTNEDAVQGVVNEEALHGVVANE--DAAQAIAKPDAAHGIAN----EGVANEVA 900 G + G+ + G +E + P + G GV Sbjct: 660 TPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSG 719 Query: 901 AQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANE 960 +G+ E G +D G + + + A ED +G + G Sbjct: 720 NRGLQGEKGEKG--EDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGP 777 Query: 961 DAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGI 1020 + G ++ G+ G G + +G + K G+ E G Sbjct: 778 PGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGS 837 Query: 1021 ANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAA 1080 E G + +G +D A GI E G+ G QG +D Sbjct: 838 RGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQG---KDGR 894 Query: 1081 QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHE 1140 G + G + G A + G E G G E + G+ Sbjct: 895 PGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGR 954 Query: 1141 DAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1200 + +G G G G +G G G Sbjct: 955 EGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGP 1014 Query: 1201 AKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATED---------VADGIANEDAA 1251 G+ + + P +G E G +D G A Sbjct: 1015 LGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGE 1074 Query: 1252 HGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANE 1311 G +V A G +G A GI G D AQG + G + Sbjct: 1075 EGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGD 1134 Query: 1312 DPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGI 1371 D ++G GV +QG+ G + + G QG Sbjct: 1135 DGVRGFV------GVIGPPGLQGLPGPPGEKGEVGDVGSMG------PHGAPGPRGPQGP 1182 Query: 1372 SKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAA 1431 + + G+ G E +G A + G G+ G + Sbjct: 1183 TGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPG------APGIPGPKGDIGEKGDSGP 1236 Query: 1432 HGIANEVAAHGIANEDAAQGIANEDAAQ---GIAHEDAVQGIANEDAVHGVAKEVAAHGV 1488 G A G ED A+G G + V GI G +V G Sbjct: 1237 SGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGP 1296 Query: 1489 ANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAV 1548 P RG + + +G E A G D G + A+G V Sbjct: 1297 PGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGP 1356 Query: 1549 HGV 1551 G+ Sbjct: 1357 EGL 1359 Score = 79.7 bits (195), Expect = 3e-14 Identities = 172/968 (17%), Positives = 260/968 (26%), Gaps = 57/968 (5%) Query: 1289 GIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANED 1348 G+ E+ A+G +QG G V G D +G+ + G D Sbjct: 500 GLKGEEGAEGPQGPRGLQGP------HGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFD 553 Query: 1349 AAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVA 1408 G+ E + G ED +G G A E +G+ G Sbjct: 554 GLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPT 613 Query: 1409 NEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQ 1468 V G+ +G G + HG QG+ +G + Sbjct: 614 GRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIP 673 Query: 1469 GIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANED 1528 G+ D G G A P G T G G ED Sbjct: 674 GLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGED 733 Query: 1529 AAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNE------D 1582 G +V +G + G ED +G + G A E+ G E Sbjct: 734 GFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQA---GQAGEEGPPGSAGEKGKLGVP 790 Query: 1583 ALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGI 1642 L +I P G + + K G+ + G E G Sbjct: 791 GLPGYPGRPGPKGSIGFP----GPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGA 846 Query: 1643 SKEDAVQGIANEDAAQGIANEDAAQGIAHEDAV------QGIANEDAVHGVAKEVAAHGV 1696 + + +G +D A GI E G+ G +D G + G Sbjct: 847 TGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGF 906 Query: 1697 ANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAA 1756 + G A QG EV G G E G+ A G Sbjct: 907 QGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGP 966 Query: 1757 QGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATE 1816 G ++G G RG G+ + Sbjct: 967 LGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQ 1026 Query: 1817 DVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGV 1876 ++G G E G + +D + G G A +G +V G Sbjct: 1027 SGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGH 1086 Query: 1877 AHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAA 1936 +G A GI G D AQ G +D V+G Sbjct: 1087 KGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFV----- 1141 Query: 1937 QGIAKEDAVQGIANEDAAQGIANEVAA---HGIANEDAAQGIANEDAAQGIAHEDAVQGI 1993 G+ +QG+ +G +V + HG QG + G+ G Sbjct: 1142 -GVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGA 1200 Query: 1994 ANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAA 2053 E G A + P A GI G + G A G ED A Sbjct: 1201 VGEKGERGDAGDPG------PPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGA 1254 Query: 2054 QAIAKPDAAHG----IANEGIATEDVADG-------IAEDAVQGITNEEAAQAIAKQDAA 2102 + P G + G++ D + G + G + E A + Sbjct: 1255 KGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGP 1314 Query: 2103 HGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANE 2162 G + +G E A+G D G + A G +G+ G E Sbjct: 1315 SGHMGREGREG---EKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLR---GIPGPVGE 1368 Query: 2163 DAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGV 2222 + G ++ G + G+ + +G + G+ G + GV Sbjct: 1369 PGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGV 1428 Query: 2223 ANEDAAQG 2230 +G Sbjct: 1429 QGPPGPKG 1436 Score = 79.3 bits (194), Expect = 4e-14 Identities = 181/997 (18%), Positives = 264/997 (26%), Gaps = 73/997 (7%) Query: 939 ITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVE 998 +T G+ G + QG G G D +G+ + Sbjct: 486 LTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTG 545 Query: 999 VQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISK 1058 +G D + G+ E G V G ED +G G A E G+ Sbjct: 546 PKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLG 605 Query: 1059 EDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQG 1118 G GI A+G G + HG G+ +G Sbjct: 606 PRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKG 665 Query: 1119 VANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDA 1178 + G+ G +G E A G G +G + Sbjct: 666 PPGNPGIPGLPGS---DGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRG 722 Query: 1179 AQ---GIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQG 1235 Q G ED G + + G + A G ED P G A E G Sbjct: 723 LQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEG---PKGQAGQAGEEGPPG 779 Query: 1236 IATEDVADGI------------ANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAK 1283 A E G+ G + G S + G+ E G Sbjct: 780 SAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRG 839 Query: 1284 EDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHG 1343 E G + +G +D G+ E + G+ G QG +D G Sbjct: 840 ERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQG---KDGRPG 896 Query: 1344 IANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDA 1403 + G + A QG + E G G E QG+ + Sbjct: 897 HPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGE---QGLPGLEG 953 Query: 1404 VQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQ---- 1459 +G E+ G ++ G+ G + G+ + G + + Sbjct: 954 REGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERG 1013 Query: 1460 --------GIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVA 1511 G+ + +G G E G +D P G A Sbjct: 1014 PLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSG 1073 Query: 1512 TQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVAN 1571 +G + A G G A GI G D QG G Sbjct: 1074 EEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKG 1133 Query: 1572 EDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAA---HSIANKDAAQGIANQD 1628 +D V+G V V Q + P G +V + H QG + Sbjct: 1134 DDGVRGFVG-------VIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSE 1186 Query: 1629 AAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVA 1688 G+ V G E +G A + G A GI G + G A Sbjct: 1187 GTPGLPGGVGQPGAVGEKGERGDAGDPGPPG------APGIPGPKGDIGEKGDSGPSGAA 1240 Query: 1689 KEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAH 1748 G ED +G + G G + V GI G +V Sbjct: 1241 GPPGKKGPPGEDGAKGSVGPTGLPGDL------GPPGDPGVSGIDGSPGEKGDPGDVGGP 1294 Query: 1749 GIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEV 1808 G G +G + E A G D P ARG V Sbjct: 1295 GPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRV 1354 Query: 1809 AAQGIATEDVADGIP---NEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQ 1865 +G+ GIP E G ++ G + G+ + +G E Sbjct: 1355 GPEGLR------GIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKG---EKGHI 1405 Query: 1866 GVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQG 1902 G+ + G A E QG+ G + G Sbjct: 1406 GLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPG 1442 Score = 78.6 bits (192), Expect = 7e-14 Identities = 185/1021 (18%), Positives = 274/1021 (26%), Gaps = 56/1021 (5%) Query: 67 GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126 G+ ++G QG HG V G D A+G+ + +G D Sbjct: 494 GLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGPKGDRGFD 553 Query: 127 AVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIA 186 + G+ E +G G ED G G A E + + + Sbjct: 554 GLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPT 613 Query: 187 NEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQ 246 GI +G G + G QG+ +G + Sbjct: 614 GRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGIP 673 Query: 247 GVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 306 G+ D G + G T E A G G +G + +QG E Sbjct: 674 GLPGSDGPLGHPGHE---GPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEK 730 Query: 307 AVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVA 366 G G+ + P G G A E+ G A E GV Sbjct: 731 GEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVP 790 Query: 367 KEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAA 426 G +G + G + + + +P G+ E G E Sbjct: 791 ---GLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQP----GLEGERGPPGSRGERGQ 843 Query: 427 QGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKE 486 G + G +D GI E G+ G QG G E Sbjct: 844 PGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGE 903 Query: 487 VAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGV 546 + G + P +G EV G G E + G+ A G Sbjct: 904 LGFQGQTGPPGPAGVLGP---QGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGE 960 Query: 547 ANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAV 606 P G G G G V +G E Sbjct: 961 LGPPGPLGKEGPAGLRGFPGPKGGPG------DPGPTGLKGDKGPPGPVGANGSPGERGP 1014 Query: 607 QGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAK 666 G A + G + + G A + + G E G +D + G + A A Sbjct: 1015 LGPAGGIGLPGQSGSEGPVGPAGKKGSRG---ERGPPGPTGKDGIPGPLGPLGPPGA-AG 1070 Query: 667 PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG 726 P G +V A G +G A GI A H G D AQG Sbjct: 1071 PSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGP-AGH--------PGPPGADGAQG 1121 Query: 727 IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDA 786 + G +D V G + G+ + G E G + G Sbjct: 1122 RRGPPGLFGQKGDDGVRGFVGVIGPPGLQG---LPGPPGEKGEVGDVGSMGPHGAPGPRG 1178 Query: 787 VQGIANEDAAHGIANEVAAHGVANEDAAQGVANE---DAAQGVANEDAVHGVANEDAAQG 843 QG + G+ V G E +G A + A G+ G + G Sbjct: 1179 PQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSG 1238 Query: 844 VAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANE-GVANEVAAQ 902 A G ED +G V L G + ++ D + G + G Sbjct: 1239 AAGPPGKKGPPGEDGAKGSVGPTGLPGDL-GPPGDPGVSGIDGSPGEKGDPGDVGGPGPP 1297 Query: 903 GIATEDVADG-IAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANED 961 G + E A G K G E + E A+G D G Sbjct: 1298 GASGEPGAPGPPGKRGPSGHMGREGRE------------GEKGAKGEPGPDGPPGRTGPM 1345 Query: 962 AAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIA 1021 A+G V +G+ + G E + G ++ G + G+ + G Sbjct: 1346 GARGPPGRVGPEGLR---GIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGLKGDTGPKGEK 1402 Query: 1022 NEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQ 1081 + G+ G + G+ G G G+A + Sbjct: 1403 GHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQK 1462 Query: 1082 G 1082 G Sbjct: 1463 G 1463 Score = 75.1 bits (183), Expect = 8e-13 Identities = 155/835 (18%), Positives = 217/835 (25%), Gaps = 51/835 (6%) Query: 63 DAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGV 122 D G+ E +G V G ED G G A E +G+ + G Sbjct: 553 DGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGP 612 Query: 123 ANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAA 182 V G+ +G G + HG QG+ + Sbjct: 613 TGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPPGNPGI 672 Query: 183 QDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANE 242 + D G +G E AQG G V+G + +QG Sbjct: 673 PGLPGSDGPLG---HPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQG---- 725 Query: 243 VEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGI 302 +G ED G + G + A G ED +G + G A E+ G Sbjct: 726 --EKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQ---AGQAGEEGPPGS 780 Query: 303 ANED---AVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANE 359 A E V G+ G P G + + G+ E G E Sbjct: 781 AGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGE 840 Query: 360 DAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVA--------------NEDAAQAIAKP 405 G + G +D G+ E L G+ +D Sbjct: 841 RGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQ 900 Query: 406 DAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGI 465 G + G A QG EV G G E G+ + A+G Sbjct: 901 RGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGE 960 Query: 466 AHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVA 525 G + G G P G +G Sbjct: 961 LGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGG 1020 Query: 526 DGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANE 585 G+ + G G E D G + G A +G + Sbjct: 1021 IGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGD 1080 Query: 586 DAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGV 645 A G G A G+ G D AQG G +D V+G Sbjct: 1081 VGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGF 1140 Query: 646 VNEDALHGVVANEDAAQAIAKPDAAHGIANEVAA---HGIANEDAAQGIANEDAAQGIAN 702 V V Q + P G +V + HG QG + G+ Sbjct: 1141 VG-------VIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPG 1193 Query: 703 EVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQG 762 V G E +G A + G GI G + G A +G Sbjct: 1194 GVGQPGAVGEKGERGDAGDPGPPG------APGIPGPKGDIGEKGDSGPSGAAGPPGKKG 1247 Query: 763 VANEDVVQGVANEVEVQ---GIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVAN 819 ED +G + G + V GI G +V G G Sbjct: 1248 PPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPG 1307 Query: 820 EDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGV---VNEEALHGV 871 +G + G E A+G G T +G V E L G+ Sbjct: 1308 PPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGI 1362 Score = 68.6 bits (166), Expect = 7e-11 Identities = 149/840 (17%), Positives = 219/840 (26%), Gaps = 52/840 (6%) Query: 1397 GVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANED 1456 G+ G+ ++G + QG HG V G D A+G+ + Sbjct: 485 GLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDT 544 Query: 1457 AAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIA 1516 +G D + G+ E G V G ED P G A E +G+ Sbjct: 545 GPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLL 604 Query: 1517 TEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQ 1576 + G G+ A+G V G QG HG Q Sbjct: 605 GPRGSPGPTGRPGVTGIDGAPGAKG---NVGPPGEPGPPGQQG------NHGSQGLPGPQ 655 Query: 1577 GVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANE 1636 G++ P GI + +G + AQG Sbjct: 656 GLIGTPGEKG-------------PPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGS 702 Query: 1637 VAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGV 1696 G V+G + QG E ED G + + G + A G Sbjct: 703 AGPPGYPGPRGVKGTSGNRGLQGEKGEKG------EDGFPGFKGDVGLKGDQGKPGAPGP 756 Query: 1697 ANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAA 1756 ED +G + G G + V G+ G + G Sbjct: 757 RGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGE 816 Query: 1757 QGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATE 1816 +G + + G+ E E G + D A GI E G+ Sbjct: 817 KGKSGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGP 876 Query: 1817 DVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGV 1876 G P G + G + G + G A QG EV G Sbjct: 877 P---GFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGE 933 Query: 1877 AHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAA 1936 G E G+ + A+G +G G Sbjct: 934 RGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGL 993 Query: 1937 QGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANE 1996 +G G +G G+ + ++G +G E G + Sbjct: 994 KGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGK 1053 Query: 1997 DAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAI 2056 D + G A P G +V A G G A G+ Sbjct: 1054 DGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGP 1113 Query: 2057 AKPDAAHGIANE-GIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVT 2115 D A G G+ + DG+ G+ Q G+ +G Sbjct: 1114 PGADGAQGRRGPPGLFGQKGDDGVR--GFVGVIGPPGLQ---------GLPGPPGEKGEV 1162 Query: 2116 NEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVE-- 2173 +V + G HG G + G+ V G E +G A + Sbjct: 1163 GDVGSMG------PHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPP 1216 Query: 2174 -VQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVA 2232 GI G + G A G ED A+G G GV+ Sbjct: 1217 GAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVS 1276 Score = 63.2 bits (152), Expect = 3e-09 Identities = 137/750 (18%), Positives = 208/750 (27%), Gaps = 47/750 (6%) Query: 1523 GIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNED 1582 G D A G+ + +G + G+ E +G V G ED +G Sbjct: 530 GRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPP 589 Query: 1583 ALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGI 1642 + A E + + P + G I A+G G + HG Sbjct: 590 G-PTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGS 648 Query: 1643 SKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPV 1702 QG+ +G G+ D G + G E A G Sbjct: 649 QGLPGPQGLIGTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTG---EKGAQGPPGSAGP 705 Query: 1703 QGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHE 1762 G V+G + +QG +G ED G +V G + A G E Sbjct: 706 PGYPGPRGVKGTSGNRGLQGE------KGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGE 759 Query: 1763 DAVQGI------ANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANE---VAAQGI 1813 D +G A E+ A E GV P + G + +G Sbjct: 760 DGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGK 819 Query: 1814 ATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEV 1873 + + G+ E G E G + + +G +D A GI E + G+ Sbjct: 820 SGKTGQPGLEGERGPPGSRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGF 879 Query: 1874 QGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQ 1933 G QG +D G + G + A QG + E G Sbjct: 880 PGPKGPPGHQG---KDGRPGHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGP 936 Query: 1934 DAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGI 1993 G E + G+ + A+G G +G G ++G Sbjct: 937 PGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGD 996 Query: 1994 ANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAA 2053 G P G+ + ++G G E G +D Sbjct: 997 KGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGI 1056 Query: 2054 QAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEA-----AQAIAKQDAAH-GITK 2107 P G A D D + +G ++ Q + A H G Sbjct: 1057 PGPLGPLGPPGAAGPSGEEGDKGD-VGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPG 1115 Query: 2108 EDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVA------------ 2155 D AQG G +D G + G+ G EV Sbjct: 1116 ADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPG 1175 Query: 2156 ---AQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDA---AQGVANEVAAHGVANEDA 2209 QG + G+ V G + +G A + A G+ G + Sbjct: 1176 PRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSG 1235 Query: 2210 AQGVANEVAAQGVANEDAAQGVANEVAVHG 2239 G A +G ED A+G + G Sbjct: 1236 PSGAAGPPGKKGPPGEDGAKGSVGPTGLPG 1265 Score = 53.9 bits (128), Expect = 2e-06 Identities = 73/389 (18%), Positives = 108/389 (27%), Gaps = 5/389 (1%) Query: 1884 GIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKED 1943 G+ G+ +G + Q G G D A+G+ + Sbjct: 485 GLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDT 544 Query: 1944 AVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVA 2003 +G D G+ E G G ED +G G A E G+ Sbjct: 545 GPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLL 604 Query: 2004 NEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQA-IAKPDAA 2062 + GI A+G G + HG Q I P Sbjct: 605 GPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEK 664 Query: 2063 HGIANEGIATEDVADG-IAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQ 2121 N GI +DG + +G T E+ AQ G +G + Q Sbjct: 665 GPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQ 724 Query: 2122 ---GVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIA 2178 G ED G +V G + A G E +G + G G Sbjct: 725 GEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEK 784 Query: 2179 HKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVH 2238 K + G+ G + G +G + + G+ E G E Sbjct: 785 GKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQP 844 Query: 2239 GVANEDAARHMAKEDAAQGIANEDAAHGI 2267 G + + +D A GI E G+ Sbjct: 845 GATGQPGPKGDVGQDGAPGIPGEKGLPGL 873 Score = 35.8 bits (81), Expect = 0.52 Identities = 30/163 (18%), Positives = 45/163 (27%) Query: 2113 GVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEV 2172 G+T G+ G G G V G D +G+ + Sbjct: 485 GLTGRPGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDT 544 Query: 2173 EVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVA 2232 +G D + G+ E +G V G ED +G G A E +G+ Sbjct: 545 GPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLL 604 Query: 2233 NEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVHG 2275 G + A+G G + HG Sbjct: 605 GPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHG 647 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 81.3 bits (199), Expect = 1e-14 Identities = 187/919 (20%), Positives = 250/919 (27%), Gaps = 59/919 (6%) Query: 1370 GISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANED 1429 G + +D G +G+ ++G A G+ G E G Sbjct: 225 GPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLK 284 Query: 1430 AAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVA 1489 +G+ E A G A G G A G D G G Sbjct: 285 GENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFP 344 Query: 1490 NEDAAHAIAKP------DAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIA 1543 A P + A G E QG A G + + G E+ GI Sbjct: 345 GSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIP 404 Query: 1544 NEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAA 1603 + G G G A E G E E I A Sbjct: 405 GAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRG----ERGEAGIPGVPGA 460 Query: 1604 HGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANE 1663 G + + + G A + A G +GI E +G A E A G A Sbjct: 461 KGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGE---KGPAGERGAPGPAGP 517 Query: 1664 DAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGV 1723 A G D V G + G + G QG + G + GV Sbjct: 518 RGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGV 577 Query: 1724 AHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAA 1783 G D A G E G G E QG + Sbjct: 578 M---GFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGP 634 Query: 1784 HGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKE 1843 G P G E +G A A G P G E G++ Sbjct: 635 PGPQGLQGLPGTGGPPGENGKPGEPGPKGDAG---APGAPGGKGDAGAPGERGPPGLAGA 691 Query: 1844 DAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGI 1903 ++G A +G +G A G A +QG+ E G +G Sbjct: 692 PGLRGGAGPPGPEGG------KGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGE 745 Query: 1904 ANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAA 1963 A + +D +G + G A Q +G + GIA + G E Sbjct: 746 PGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGP 805 Query: 1964 HGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANE 2023 G A A G E +G E G E GVA A P +G+ E Sbjct: 806 PGPAGFPGAPGQNGEPGGKG---ERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGE 862 Query: 2024 VAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDA 2083 + G G A A G+ + P G + DG A Sbjct: 863 RGSPG------GPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGK--------DGPPGPA 908 Query: 2084 VQGITNEEAAQAIA--KQDAAH-GITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHG 2140 G T + ++ K DA G AQG G+A A G+A G Sbjct: 909 --GNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPG 966 Query: 2141 VANEDAAQGVANE---VAAQGVANE---------DAVQGVANEVEVQGIAHKDAIQGIAN 2188 QGV E A G++ E + G A E G D + G Sbjct: 967 PRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDG 1026 Query: 2189 EDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARH 2248 +G E + G G V G + + G A G A A Sbjct: 1027 SPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPG 1086 Query: 2249 MAKEDAAQGIANEDAAHGI 2267 +G E A GI Sbjct: 1087 PQGPRGDKGETGERGAAGI 1105 Score = 80.1 bits (196), Expect = 2e-14 Identities = 199/1002 (19%), Positives = 259/1002 (25%), Gaps = 59/1002 (5%) Query: 1190 GIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANE- 1248 G A G + G A +D RG+ +G A G+ Sbjct: 207 GQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHR 266 Query: 1249 --DAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQ 1306 D +G E A G+ E+ G+ E+ A G G G A Sbjct: 267 GFDGRNGEKGETGAPGLKGEN---GLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGND 323 Query: 1307 GVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANED 1366 G D G G A G E G + A G E Q A Sbjct: 324 GARGSDGQPGPPGP---PGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQ 380 Query: 1367 AAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIA 1426 G + G E GI + G G ++G A E G Sbjct: 381 GPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAK 440 Query: 1427 NEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAH 1486 E G E GI A+G +D + G + + G A E G + Sbjct: 441 GEPGPRGERGEA---GIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPN 497 Query: 1487 GVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEV 1546 G+ E P RG +G A E DG+ G+ G + Sbjct: 498 GIPGEKG------PAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKP 551 Query: 1547 AVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGI 1606 G E G G G D E P G Sbjct: 552 GPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGK-NGERGGPGGPGPQGPPGK 610 Query: 1607 ANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAA 1666 E G G G G E +G A A Sbjct: 611 NGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGA 670 Query: 1667 QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHE 1726 G DA G E G+A G A G + +G A G A Sbjct: 671 PG-GKGDA--GAPGERGPPGLAGAPGLRGGA------GPPGPEGGKGAAGPPGPPGAAGT 721 Query: 1727 DAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGV 1786 +QG+ E G G A G+ +D +G A + G Sbjct: 722 PGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGE 781 Query: 1787 ANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAV 1846 IA P + G E G A G P ++ G E A G E Sbjct: 782 GGAPGLPGIAGPRGSPGERGETGPPGPAG---FPGAPGQNGEPGGKGERGAPGEKGEGGP 838 Query: 1847 QGIANEDAAQGIAKEDPIQGVANEVEVQG---VAHEDAVQGIANEDAAHGIANEDAAQGI 1903 G+A G A QGV E G A +G+ ++G G Sbjct: 839 PGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGS 898 Query: 1904 ANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAA 1963 +D A A G +G A Q +G AQG Sbjct: 899 PGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKG------------SPGAQGPPGAPGP 946 Query: 1964 HGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANE 2023 GIA A+G+A G QG+ E G P G+A Sbjct: 947 LGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGT 1006 Query: 2024 VAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDA 2083 G +DG+ D + G + P A + G G A Sbjct: 1007 AGEPGRDGNPGSDGLPGRDGSPGGKGDRGENG--SPGAPGAPGHPG------PPGPVGPA 1058 Query: 2084 VQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVAN 2143 G + + A A G A G +G E A G+ G Sbjct: 1059 --GKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGH---RGFPG 1113 Query: 2144 EDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQG 2185 A G QG G V G KD G Sbjct: 1114 NPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSG 1155 Score = 79.7 bits (195), Expect = 3e-14 Identities = 201/1041 (19%), Positives = 280/1041 (26%), Gaps = 73/1041 (7%) Query: 1073 GIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEV 1132 G A +D G +G+ + G A G+ ++G D G E Sbjct: 225 GPAGKDGESGRPGRPGERGLPGPPGIKGPA------GIPGFPGMKGHRGFDGRNGEKGET 278 Query: 1133 EVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIA 1192 G+ E+ + G +G + G E G+ A+G G Sbjct: 279 GAPGLKGENGLPG------ENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQP 332 Query: 1193 NEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAH 1252 G A + G E + A G E QG A G + + Sbjct: 333 GPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSP 392 Query: 1253 GVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANED 1312 G E+ GI + G G ++G A E G E +G E Sbjct: 393 GGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEA 452 Query: 1313 PIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGIS 1372 I GV G ED G E A+G+ G A E A GI Sbjct: 453 GIPGVP------GAKGEDGKDGSPGEPGANGLP------GAAGERGAPGFRGPAGPNGIP 500 Query: 1373 KEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAH 1432 E +G A E A G A +G A E GV ++G+ G + Sbjct: 501 GE---KGPAGERGAPGPAGP---RGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPP 554 Query: 1433 GIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANED 1492 G E G +G G D G E G G E Sbjct: 555 GSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGET 614 Query: 1493 AAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVA 1552 P G + G G +G E +G A G Sbjct: 615 GPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGK 674 Query: 1553 IEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAA 1612 + G E G+A ++G + + A P G A Sbjct: 675 GDAGAPG---ERGPPGLAGAPGLRGGAGPPG-------PEGGKGAAGPPGPPGAAGTPGL 724 Query: 1613 HSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHE 1672 + + G +G A G+ +D +G G A + +G Sbjct: 725 QGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGA 784 Query: 1673 DAVQGIANEDAVHGVAKEVAAHGVA--------NEDP-------VQGVANEDAVQGVANE 1717 + GIA G E G A N +P G E GVA Sbjct: 785 PGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGP 844 Query: 1718 VEVQGVAHEDAVQGIANE---DAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAV 1774 G A QG+ E G A G+ + G G +D Sbjct: 845 PGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGP 904 Query: 1775 HSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANE 1834 A A G + ++ P G E + G A G P G+A Sbjct: 905 PGPAGNTGAPG------SPGVSGPKGDAGQPGEKGSPG------AQGPPGAPGPLGIAGI 952 Query: 1835 VAAHGISKEDAVQGIANEDAAQGIAKED---PIQGVANEVEVQGVAHEDAVQGIANEDAA 1891 A G++ + G QG+ E G++ E G + G A E Sbjct: 953 TGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGR 1012 Query: 1892 HGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANE 1951 G D G + E+ + G G G + + G A Sbjct: 1013 DGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGP 1072 Query: 1952 DAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAI 2011 A G A A G +G E A GI G G A + A Sbjct: 1073 AGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGS 1132 Query: 2012 AKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIA 2071 P RG G G G E ++ G A Sbjct: 1133 PGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGA 1192 Query: 2072 TEDVADGIAEDAVQGITNEEA 2092 G+ A+ GI E+A Sbjct: 1193 PGPCCGGVGAAAIAGIGGEKA 1213 Score = 78.2 bits (191), Expect = 9e-14 Identities = 186/962 (19%), Positives = 262/962 (27%), Gaps = 54/962 (5%) Query: 403 AKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAA 462 A P G + G A +D G G+ ++G A GI Sbjct: 209 AGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPA------GIPGFPGM 262 Query: 463 QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATE 522 +G D G E G+ E +G+ ++ A P A G G A Sbjct: 263 KGHRGFDGRNGEKGETGAPGLKGE---NGLPGENGAPGPMGPRGAPGERGRPGLPGAAGA 319 Query: 523 DVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKP------DAAHGIANEVATQGIATE 576 DG D G G A P + A G E QG A Sbjct: 320 RGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGA 379 Query: 577 DVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGV 636 G + + G E+ G+ + G G +G A E +G Sbjct: 380 QGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGA 439 Query: 637 ANEDAVQGVVNEDALHGV--VANEDAAQAIAKPDAAHGI---ANEVAAHGIANEDAAQGI 691 E +G E + GV ED A+G+ A E A G GI Sbjct: 440 KGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGI 499 Query: 692 ANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAA 751 E +G A E A G + +G A E G+ ++G+ G + Sbjct: 500 PGE---KGPAGERGAPGPA---GPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGP 553 Query: 752 HGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANE 811 G E G +G + G D G E G G E Sbjct: 554 PGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGE 613 Query: 812 DAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGV 871 QG G + G G +G E +G G Sbjct: 614 TGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGG 673 Query: 872 VANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIA-KDAAHGITKEEAAQAI 930 + A P A G A +G G A G Q + Sbjct: 674 KGDAGAPGERGPPGLAGAPGLRGGAGPPGPEG------GKGAAGPPGPPGAAGTPGLQGM 727 Query: 931 AKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAV 990 + +G A GV +D +G + G A + G + Sbjct: 728 PGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGL 787 Query: 991 QGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANE 1050 G+A G + G A A G E G E A G E G+A Sbjct: 788 PGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKG---ERGAPGEKGEGGPPGVAGP 844 Query: 1051 VAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGV 1110 G + QG+ E + G G A +G+ +G G Sbjct: 845 PGGSGPAGPPGPQGVKGERGSPG------GPGAAGFPGARGLPGPPGSNGNPGPPGPSGS 898 Query: 1111 ANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAA 1170 +D G A G V G + G A G GIA A Sbjct: 899 PGKDGPPGPAGNTGAPGSPG---VSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGA 955 Query: 1171 QGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANE 1230 +G+A G QG+ E G A+G++ E P G+A Sbjct: 956 RGLAGPPGMPGPRGSPGPQGVKGESGKPG------ANGLSGERGPPG---PQGLPGLAGT 1006 Query: 1231 VAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGI 1290 G +DG+ D + G + +G G G A + +G Sbjct: 1007 AGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGE 1066 Query: 1291 ANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAA 1350 + G +G +G E +G A +G A G Sbjct: 1067 SGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQ 1126 Query: 1351 QG 1352 QG Sbjct: 1127 QG 1128 Score = 76.6 bits (187), Expect = 3e-13 Identities = 193/998 (19%), Positives = 265/998 (26%), Gaps = 46/998 (4%) Query: 256 GIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEV 315 G A G + G A +D G +G+ ++G A G+ Sbjct: 207 GQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMK--- 263 Query: 316 AAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKEVTAHGVA 375 G D + A G+ E G+ E+ A G A G G A Sbjct: 264 ---GHRGFDGRNGEKGETGAPGLKGE---NGLPGENGAPGPMGPRGAPGERGRPGLPGAA 317 Query: 376 NEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAH--GIANEVAAHGIANEDAAQGIANEV 433 G D G A P A G A ++G + G Sbjct: 318 GARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHA 377 Query: 434 AAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVA 493 A G + G G A A G+ G A + G+ G Sbjct: 378 GAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLR---GGAGEP 434 Query: 494 NKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAH 553 K+ A P RG A G ED DG E +G+ G A E A Sbjct: 435 GKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLP------GAAGERGAP 488 Query: 554 AIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANED 613 P +GI E +G A E A G A G A E GV ++G+ Sbjct: 489 GFRGPAGPNGIPGE---KGPAGERGAPGPAGP---RGAAGEPGRDGVPGGPGMRGMPGSP 542 Query: 614 AVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGI 673 G + G E G +G G N+ A + G Sbjct: 543 GGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGP 602 Query: 674 ANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAV 733 + G E QG G + G + G G E Sbjct: 603 GPQ-GPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGP 661 Query: 734 QGIANEDAVHGVAKEVAAHG------VANEDPVQGVANE---DVVQGVANEVEVQGIAHE 784 +G A G + A G +A ++G A + +G A G A Sbjct: 662 KGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGT 721 Query: 785 DAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGV 844 +QG+ E G G A GV +D +G G A + +G Sbjct: 722 PGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGE 781 Query: 845 AKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGI 904 G+ G E G A +P G E G+ Sbjct: 782 GGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGV 841 Query: 905 ATEDVADGIA-KDAAHGITKEEAAQA---IAKQDAAHSITNEDAAQGVANEDAAHGVANE 960 A G A G+ E + A A + + G G + Sbjct: 842 AGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGK 901 Query: 961 DAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGI 1020 D G A A G G A + +G QG GIA A G+ Sbjct: 902 DGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPG---AQGPPGAPGPLGIAGITGARGL 958 Query: 1021 ANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAA 1080 A G QG+ E G G + G+A G + Sbjct: 959 AGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGS 1018 Query: 1081 QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHE 1140 G+ D G + +G A G G A + +G + G Sbjct: 1019 DGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGP 1078 Query: 1141 DAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1200 +G G E G A +G A G QG G Sbjct: 1079 AGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGP 1138 Query: 1201 AKEVAAHGVANEDAAH---AIAKPDAARGIANEVAAQG 1235 V G +D P RG E ++G Sbjct: 1139 RGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEG 1176 Score = 76.3 bits (186), Expect = 3e-13 Identities = 173/880 (19%), Positives = 236/880 (26%), Gaps = 68/880 (7%) Query: 668 DAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGI 727 D +G E A G+ E+ G+ E+ A G A G + G A G Sbjct: 269 DGRNGEKGETGAPGLKGEN---GLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGA 325 Query: 728 AHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAV 787 D G G A G E G + G E QG A Sbjct: 326 RGSDGQPGPPGPPGTAGFPGSPGAKG---EVGPAGSPGSNGAPGQRGEPGPQGHAGAQGP 382 Query: 788 QGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKE 847 G + + G E+ G+ G G + G A E G E Sbjct: 383 PGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGE 442 Query: 848 VTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATE 907 G E + GV + ED A+G+ G A E A G Sbjct: 443 PGPRGERGEAGIPGVPGAKG-------EDGKDGSPGEPGANGLP--GAAGERGAPGFRGP 493 Query: 908 DVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVA 967 +GI + +G A E A G A +G A Sbjct: 494 AGPNGIPGE-----------------------------KGPAGERGAPGPAGP---RGAA 521 Query: 968 NEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAH 1027 E GV + G+ G + G + G G + Sbjct: 522 GEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFP 581 Query: 1028 GIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHED 1087 G D A G E G G + E QG G + G Sbjct: 582 GPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPG---PQ 638 Query: 1088 AVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIA 1147 +QG+ G + G + G G E G+A ++G A Sbjct: 639 GLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGA 698 Query: 1148 NEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAH 1207 G G A G A QG+ E G G A Sbjct: 699 GPPGPEG------GKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGAD 752 Query: 1208 GVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKED 1267 GV +D P G A + +G GIA + G E G + Sbjct: 753 GVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFP 812 Query: 1268 AVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANE---VEVQ 1324 G E +G E G E G+A G A QGV E Sbjct: 813 GAPGQNGEPGGKG---ERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGP 869 Query: 1325 GVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANED 1384 G A +G+ ++G G +D A A G +G A + Sbjct: 870 GAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQP 929 Query: 1385 AAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANE---VAAH 1441 +G QG G+A +G+A + G G+ E A+ Sbjct: 930 GEKG---SPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGAN 986 Query: 1442 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPD 1501 G++ E G G A E G D + G G E+ + Sbjct: 987 GLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAP 1046 Query: 1502 AARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQG 1541 G V G + + G A A G A A G Sbjct: 1047 GHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPG 1086 Score = 73.9 bits (180), Expect = 2e-12 Identities = 180/895 (20%), Positives = 231/895 (25%), Gaps = 52/895 (5%) Query: 406 DAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGI 465 D +G E A G+ E+ G G +G A G D A+G Sbjct: 269 DGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARG- 327 Query: 466 AHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVA 525 D G G A G + + A G E QG A Sbjct: 328 --SDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPG---SNGAPGQRGEPGPQGHAGAQGP 382 Query: 526 DGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANE 585 G + G E+ G+ P G +G A E +G E Sbjct: 383 PGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGE 442 Query: 586 DAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGV 645 G E + GV G ED G E A G+ G A E G Sbjct: 443 PGPRGERGEAGIPGVP------GAKGEDGKDGSPGEPGANGLP------GAAGERGAPGF 490 Query: 646 VNEDALHGVVANEDAAQAIAKPDAA--HGIANEVAAHGIANEDAAQGIANEDAAQGIANE 703 +G+ + A P A G A E G+ +G+ G + Sbjct: 491 RGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGK 550 Query: 704 VAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGV 763 G E G +G G D G E G G Sbjct: 551 PGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGK 610 Query: 764 ANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAA 823 E QG G + G G +G E +G A A Sbjct: 611 NGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGA 670 Query: 824 QGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAK 883 G DA G E G+A G +G G Sbjct: 671 PG-GKGDA--GAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGM 727 Query: 884 PDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNED 943 P G+ + G + G D G KD G T A Q Sbjct: 728 PGERGGLGSPGPKGDKGEPGGPGADGVPG--KDGPRGPTGPIGPPGPAGQPGDKGEGGAP 785 Query: 944 AAQGVANEDAAHGVANEDAAQGVAN---------------EVAAQGVANEDAVHGVANED 988 G+A + G E G A E A G E GVA Sbjct: 786 GLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPP 845 Query: 989 AVQGVANEVEVQGIAHKDAIQG---IANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQ 1045 G A QG+ + G A A G+ ++G G +D Sbjct: 846 GGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPP 905 Query: 1046 GIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEV 1105 G A A G +G A + +G AQG GIA G+A Sbjct: 906 GPAGNTGAPGSPGVSGPKGDAGQPGEKG---SPGAQGPPGAPGPLGIAGITGARGLAGPP 962 Query: 1106 AAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIA 1165 G QGV E G +G + G+A G A E G Sbjct: 963 GMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLA------GTAGEPGRDGNP 1016 Query: 1166 NEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAR 1225 D G +G E+ G G V G + + A P A Sbjct: 1017 GSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAP 1076 Query: 1226 GIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQG 1280 G A A G G E A G+ G G A + A G Sbjct: 1077 GPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIG 1131 Score = 73.2 bits (178), Expect = 3e-12 Identities = 165/800 (20%), Positives = 213/800 (26%), Gaps = 47/800 (5%) Query: 67 GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126 GI +G G A G A+G G + A+G Sbjct: 387 GINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPR 446 Query: 127 AVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIA 186 +G A V G ED G E A+G+ G A E A I Sbjct: 447 GERGEAGIPGVPGAKGEDGKDGSPGEPGANGL------PGAAGERGAPGFRGPAGPNGIP 500 Query: 187 NEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQ 246 E G +G +G A E GV ++G+ G + Sbjct: 501 GEKGPAG------ERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPP 554 Query: 247 GVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 306 G E G G + G D A G E G G E Sbjct: 555 GSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGET 614 Query: 307 AVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVA 366 G G + P G+ T G E +G E G A Sbjct: 615 GPQGPPGPTGPGGDKGDTG------PPGPQGLQGLPGTGGPPGE---NGKPGEPGPKGDA 665 Query: 367 KEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAA 426 A G + G L G A P+ G A G A Sbjct: 666 GAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGA-GPPGPEGGKGAAGPPGPPGAAGTPGL 724 Query: 427 QGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKE 486 QG+ E G +G E G A G+ +D +G G A + Sbjct: 725 QGMPGERGGLG---SPGPKGDKGEPGGPG------ADGVPGKDGPRGPTGPIGPPGPAGQ 775 Query: 487 VAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGV 546 G IA P + G E G A A G ++ G E A G Sbjct: 776 PGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPG---QNGEPGGKGERGAPGE 832 Query: 547 ANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAV 606 E +A P G A QG+ E + G G A G+ Sbjct: 833 KGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPG------GPGAAGFPGARGLPGPPGS 886 Query: 607 QGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAK 666 G G +D G A A G +G + G AQ Sbjct: 887 NGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKG----SPGAQGPPG 942 Query: 667 PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANE---VAAHGISKEDAVQGIANEDA 723 GIA A G+A G QG+ E A+G+S E G Sbjct: 943 APGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPG 1002 Query: 724 AQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAH 783 G A E G D + G G E+ G G V G + Sbjct: 1003 LAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSG 1062 Query: 784 EDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQG 843 + G A A G A A G +G E A G+ G + G Sbjct: 1063 DRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPG 1122 Query: 844 VAKEVTAHGVTNEDAVQGVV 863 A + A G +G V Sbjct: 1123 PAGQQGAIGSPGPAGPRGPV 1142 Score = 70.1 bits (170), Expect = 2e-11 Identities = 171/866 (19%), Positives = 227/866 (26%), Gaps = 74/866 (8%) Query: 1424 GIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEV 1483 G A +D G G+ +G A G+ G E G Sbjct: 225 GPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLK 284 Query: 1484 AAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIA 1543 +G+ E+ A P A G G A DG D G G Sbjct: 285 GENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFP 344 Query: 1544 NEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAA 1603 G E G A G E QG AQ P Sbjct: 345 GSPGAKG---EVGPAGSPGSNGAPGQRGEPGPQG-------------HAGAQGPPGPPGI 388 Query: 1604 HGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANE 1663 +G A A G+ G A A G+ +G A E G E Sbjct: 389 NGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGL------RGGAGEPGKNGAKGE 442 Query: 1664 DAAQGIAHEDAVQGIAN---EDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEV 1720 +G E + G+ ED G E A+G+ G A E G Sbjct: 443 PGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLP------GAAGERGAPGFRGPAGP 496 Query: 1721 QGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKE 1780 G+ E +G A E A G G A E G+ ++G+ + Sbjct: 497 NGIPGE---KGPAGERGAPG---PAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGK 550 Query: 1781 VAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGI 1840 G E P RG + G DG P ++ G G Sbjct: 551 PGPPGSQGESGRPGPPGPSGPRG---QPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGP 607 Query: 1841 SKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAA 1900 ++ G G + G +QG+ G +G E Sbjct: 608 PGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLP------GTGGPPGENGKPGEPGP 661 Query: 1901 QGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANE 1960 +G A A + A G E G+A +G A G + +G A Sbjct: 662 KGDAGAPGAPGGKGDAGAPG---ERGPPGLAGAPGLRGGA------GPPGPEGGKGAAGP 712 Query: 1961 VAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGI 2020 G A QG+ E G +G GV +D P G Sbjct: 713 PGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGP 772 Query: 2021 ANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIA 2080 A + +G GIA + G E A A G E G Sbjct: 773 AGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGE-------PGGKG 825 Query: 2081 EDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHG 2140 E G E +A G QGV E + G G A A G Sbjct: 826 ERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPG------GPGAAGFPGARG 879 Query: 2141 VANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDA------AQG 2194 + + G G +D G A G +G A + AQG Sbjct: 880 LPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQG 939 Query: 2195 VANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDA 2254 G+A A+G+A G QGV E G R Sbjct: 940 PPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQG 999 Query: 2255 AQGIANEDAAHGIANEDAVHGIANED 2280 G+A G G+ D Sbjct: 1000 LPGLAGTAGEPGRDGNPGSDGLPGRD 1025 Score = 58.5 bits (140), Expect = 7e-08 Identities = 142/717 (19%), Positives = 181/717 (25%), Gaps = 51/717 (7%) Query: 66 HGITNEDAVQGVANEVAAQGVAN---EDAAHGVANEVAAHGV---ANEDAAQGVANEVAA 119 +G E +G E GV ED G E A+G+ A E A G Sbjct: 437 NGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGP 496 Query: 120 QGVANED---AVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDI 176 G+ E +G +G A E G+ G+ G + Sbjct: 497 NGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGS 556 Query: 177 AKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAV 236 E +G G D A G E G G E Sbjct: 557 QGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGP 616 Query: 237 QGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHE 296 QG G + G G +G E +G A A G + Sbjct: 617 QGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGD 676 Query: 297 DAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATE------ 350 G + G G + A P G A QG+ E Sbjct: 677 AGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGS 736 Query: 351 ------------DVADGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDA 398 ADG+ +D G + G A + +G L G Sbjct: 737 PGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPG------- 789 Query: 399 AQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAH 458 IA P + G E G A A G E G E G E G+A Sbjct: 790 ---IAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKG---ERGAPGEKGEGGPPGVAG 843 Query: 459 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQG 518 G A QG+ E G G A A + P + G G Sbjct: 844 PPGGSGPAGPPGPQGVKGERGSPG------GPGAAGFPGARGLPGPPGSNGNPGPPGPSG 897 Query: 519 IATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDV 578 +D G A G G A + A G GIA Sbjct: 898 SPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKG---SPGAQGPPGAPGPLGIAGITG 954 Query: 579 ADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVAN 638 A G+A G GV E G G G+A G Sbjct: 955 ARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDG 1014 Query: 639 EDAVQGVVNEDALHGVVANEDAAQAIAKPDAA--HGIANEVAAHGIANEDAAQGIANEDA 696 G+ D G + + P A G V G + + G A Sbjct: 1015 NPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAG 1074 Query: 697 AQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHG 753 A G A A G +G E A GI G G A + A G Sbjct: 1075 APGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIG 1131 Score = 45.1 bits (105), Expect = 8e-04 Identities = 94/465 (20%), Positives = 121/465 (26%), Gaps = 30/465 (6%) Query: 1798 PDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANE--DAA 1855 P A N QG + GIP + G+ + + G GI Sbjct: 92 PTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPG---SPGPPGICESCPTGP 148 Query: 1856 QGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANE 1915 Q + + V + V V G+A G A G G Q E Sbjct: 149 QNYSPQYDSYDVKSGVAVGGLA---GYPGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGE 205 Query: 1916 DAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGI 1975 G S G G E G E G GI +G Sbjct: 206 PGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGH 265 Query: 1976 ANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVA 2035 D G E G+ E+ G+ E+ A P A G G A Sbjct: 266 RGFDGRNGEKGETGAPGLKGEN---GLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGN 322 Query: 2036 DGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQA 2095 DG D G A G A + G E Q Sbjct: 323 DGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGP-------AGSPGSNGAPGQRGEPGPQG 375 Query: 2096 IAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVA 2155 A G + + G E+ G+ G G +G A E Sbjct: 376 HAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPG 435 Query: 2156 AQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGV---ANEDAAQG 2212 G E +G E + G+ G ED G E A+G+ A E A G Sbjct: 436 KNGAKGEPGPRGERGEAGIPGVP------GAKGEDGKDGSPGEPGANGLPGAAGERGAPG 489 Query: 2213 VANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQG 2257 G+ E +G A E G A A D G Sbjct: 490 FRGPAGPNGIPGE---KGPAGERGAPGPAGPRGAAGEPGRDGVPG 531 >gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] Length = 1860 Score = 77.0 bits (188), Expect = 2e-13 Identities = 157/875 (17%), Positives = 251/875 (28%), Gaps = 70/875 (8%) Query: 581 GIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANED 640 G++ A G ++ + G++ G G A QG G Sbjct: 679 GLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQG------QPGPEGSP 732 Query: 641 AVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGI 700 +G L G V + P + G G+ D +G+ +G Sbjct: 733 GAKGYPGRQGLPGPVGDPG-------PKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGK 785 Query: 701 ANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPV 760 G+ E G+ G+ V G+ + GV + G + Sbjct: 786 MGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGD---LGVLGPIGYPGPKGMKGL 842 Query: 761 QGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANE 820 G E ++G E V G++ + QG G G + +G Sbjct: 843 MGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGF 902 Query: 821 DAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQA 880 G G ++ +G+ + A G+ G +E G Sbjct: 903 PGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMG---------- 952 Query: 881 IAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAH-GITKEEAAQAIAKQDAAHSI 939 P A G+ EG G D G D G E+ I Sbjct: 953 ---PPGAPGL--EGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGI 1007 Query: 940 TNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEV 999 E +G+ GV + G G E G G+ Sbjct: 1008 VGEKGDRGMMGPP---GVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGR 1064 Query: 1000 QGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKE 1059 +G D G A E + G+ G QG+A E G G S Sbjct: 1065 RGPRGPD---GPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGP 1121 Query: 1060 DAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVA---KEVAAHGVANEDPV 1116 +G+ E QG G G E + G A ++ G E + Sbjct: 1122 PGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGL 1181 Query: 1117 QGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANE 1176 G E ++G + + G+ + +G D HG + G G+ Sbjct: 1182 IGQRGEPGLEGDSGPMGPDGLKGD---RGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGV 1238 Query: 1177 DAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGI 1236 +G + + +G G ++ GV + P +RG A G Sbjct: 1239 RGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGR 1298 Query: 1237 ATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAA 1296 G+A D G+ + G E QG + A+G +G + Sbjct: 1299 MGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQG--EDGKAEGPPGPPGDRGPVGDRGD 1356 Query: 1297 QGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANE 1356 +G E G ++ +QG+ + QG +G + G QG A Sbjct: 1357 RG---EPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKA-- 1411 Query: 1357 DAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGV 1416 G VQG+ +G+ ++G+A D + G G Sbjct: 1412 -------------GAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPG------RDGQ 1452 Query: 1417 AHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQG 1451 A + QG + G A + G+A AQG Sbjct: 1453 AGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQG 1487 Score = 72.8 bits (177), Expect = 4e-12 Identities = 156/869 (17%), Positives = 249/869 (28%), Gaps = 62/869 (7%) Query: 1379 GIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEV 1438 G+ A+G K DP G++ A G ++ + G++ G G A Sbjct: 664 GLPGPPGAKG-QKGDP--GLSPGKAHDGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHP 720 Query: 1439 AAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIA 1498 G + + G QG+ G G+ G+ D + Sbjct: 721 GEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLP---GLFGLPGSDGERGLP 777 Query: 1499 KPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQ 1558 RG G+ E G+ G+ G+ ++ V G + Sbjct: 778 GVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPK 837 Query: 1559 GV------VKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAA 1612 G+ V E G E V GV + + +Q + A G + Sbjct: 838 GMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQG----DKGSQGLPGFPGARGKPGPLG- 892 Query: 1613 HSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHE 1672 + +K + G +G ++ G ++ +G+ + A+G+ G + Sbjct: 893 -KVGDKGSI-GFPGPPGPEGFPGDIGPPG---DNGPEGMKGKPGARGLPGPRGQLGPEGD 947 Query: 1673 DAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGI 1732 + G + G G D V+G + G E G GI Sbjct: 948 EGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGI 1007 Query: 1733 ANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAA 1792 E G+ + G+ + G G E G+ Sbjct: 1008 VGEKGDRGM---MGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGR 1064 Query: 1793 HAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANE 1852 PD G A E ++G+ G P GVA E G + G + Sbjct: 1065 RGPRGPD---GPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGP 1121 Query: 1853 DAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDI 1912 +G+ E QG + G G E G A G Q + Sbjct: 1122 PGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGL 1181 Query: 1913 ANEDAAQGISKE------DAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGI 1966 + G+ + D ++G G E +G+ ED G G Sbjct: 1182 IGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGP 1241 Query: 1967 ANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAA 2026 + QG A+G +G + GV + P +RG A Sbjct: 1242 EGKSGKQGEKGRTGAKG------AKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGA 1295 Query: 2027 QGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAE--DAV 2084 G G+A D G+ + P +G E DG AE Sbjct: 1296 PGRMGAQGEPGLAGYDGHKGIVG-----PLGPP------GPKGEKGEQGEDGKAEGPPGP 1344 Query: 2085 QGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANE 2144 G + + G ++ QG+ + QG G + G Sbjct: 1345 PGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGP 1404 Query: 2145 DAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGV 2204 QG A G VQG+ +G+ + ++GIA D G + G Sbjct: 1405 KGKQGKA------GAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGE 1458 Query: 2205 ANED---AAQGVANEVAAQGVANEDAAQG 2230 +D G A + GVA AQG Sbjct: 1459 QGDDGDPGPMGPAGKRGNPGVAGLPGAQG 1487 Score = 70.5 bits (171), Expect = 2e-11 Identities = 146/875 (16%), Positives = 244/875 (27%), Gaps = 59/875 (6%) Query: 607 QGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAK 666 +G + G+ D +G+ G GV E G+ N + Sbjct: 756 RGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGEL-GLPG 814 Query: 667 PDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG 726 P G+ ++ G +G+ +G+ V G+ + QG+ G Sbjct: 815 PPGVPGLIGDLGVLGPIGYPGPKGM------KGLMGSVGEPGLKGDKGEQGVPGVSGDPG 868 Query: 727 IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDA 786 + QG+ G + G + G +G ++ G ++ Sbjct: 869 FQGDKGSQGLPGFPGARGKPGPL---GKVGDKGSIGFPGPPGPEGFPGDIGPPG---DNG 922 Query: 787 VQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAK 846 +G+ + A G+ G ++ G +G G D +G Sbjct: 923 PEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPG 982 Query: 847 EVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIAT 906 + G E G + G+V + + P + G G Sbjct: 983 DPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPG 1042 Query: 907 EDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGV 966 E G + G A+ E ++G+ G QGV Sbjct: 1043 EPGPQG--PPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGV 1100 Query: 967 ANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAA 1026 A E G + G + +G+ E QG G G E Sbjct: 1101 AGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGL 1160 Query: 1027 HGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHE 1086 G A G QG+ + G+ + G D +G + G E Sbjct: 1161 PGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMG---PDGLKGDRGDPGPDGEHGE 1217 Query: 1087 DAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGI 1146 +G+ ED G G + QG +G +G + G+ Sbjct: 1218 KGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGA------KGYQGQLGEMGV 1271 Query: 1147 ANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAA 1206 + G + G A G G+A D +GI G E Sbjct: 1272 PGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGE 1331 Query: 1207 HGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKE 1266 G + A P RG + +G E G + Sbjct: 1332 QG--EDGKAEGPPGPPGDRGPVGDRGDRG---------------------EPGDPGYPGQ 1368 Query: 1267 DAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVA---NEDPIQGVANEVEV 1323 + VQG+ + QG +G ++G QG A +QG+ Sbjct: 1369 EGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGP 1428 Query: 1324 QGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANE 1383 +GV ++GIA D G + QG +D +G V G+ Sbjct: 1429 RGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRG---NPGVAGLPGA 1485 Query: 1384 DAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGI 1443 G E + G +G + G QG G + E+ G+ Sbjct: 1486 QGPPGFKGESGLPGQLGPPGKRGTEGRTGLPG------NQGEPGSKGQPGDSGEMGFPGM 1539 Query: 1444 ANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHG 1478 A +G + +GI G+ ++ + G Sbjct: 1540 AGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVG 1574 Score = 61.6 bits (148), Expect = 9e-09 Identities = 120/706 (16%), Positives = 192/706 (27%), Gaps = 57/706 (8%) Query: 1623 GIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 1682 G+ D +G+ G G+ E G+ G+ V G+ + Sbjct: 766 GLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDL 825 Query: 1683 AVHGVAKEVAAHGV------ANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANED 1736 V G G+ E ++G E V GV+ + QG + G Sbjct: 826 GVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGAR 885 Query: 1737 AAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANE------D 1790 G +V G G G ++ + + A G+ + Sbjct: 886 GKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPE 945 Query: 1791 AAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIA 1850 P A G+ + +G DG+ E G V G G+ Sbjct: 946 GDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGPVGEQGFM---GFIGLV 1002 Query: 1851 NEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQ 1910 E G + + G +G + G G ++G A+ Sbjct: 1003 GEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAK 1062 Query: 1911 DIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANED 1970 G + E +G+ QG QG+A E G G + Sbjct: 1063 GRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPP 1122 Query: 1971 AAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIA 2030 +G+ E QG G G E A G QG+ Sbjct: 1123 GTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLI 1182 Query: 2031 TEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGI-ANEGIATEDVADG----------- 2078 + G+ + G + PD HG EG+ ED G Sbjct: 1183 GQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPE 1242 Query: 2079 --IAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEV 2136 + +G T + A+ Q G+ + G ++G A G Sbjct: 1243 GKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQ 1302 Query: 2137 AAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQ--------------------- 2175 G+A D +G+ + G E QG + E Sbjct: 1303 GEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGD 1362 Query: 2176 -GIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANE 2234 G ++ +QG+ + QG G ++G QG A +GV Sbjct: 1363 PGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGV--- 1419 Query: 2235 VAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAVHGIANED 2280 G+ R + +GIA D G + G +D Sbjct: 1420 ---QGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDD 1462 Score = 61.2 bits (147), Expect = 1e-08 Identities = 149/871 (17%), Positives = 244/871 (28%), Gaps = 79/871 (9%) Query: 355 GIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANE 414 G+ D G+ G GV E G+ N + P G+ + Sbjct: 766 GLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGEL-GLPGPPGVPGLIGD 824 Query: 415 VAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGI 474 + G +G+ + + G E ++G E G++ + QG + G Sbjct: 825 LGVLGPIGYPGPKGMKGLMGSVG---EPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGF 881 Query: 475 ANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAV 534 G +V G + P G ++ G ++ +G+ + Sbjct: 882 PGARGKPGPLGKVGDKG------SIGFPGPPGPEGFPGDIGPPG---DNGPEGMKGKPGA 932 Query: 535 HGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANE 594 G+ G ++ P A G+ + +G DG+ E G Sbjct: 933 RGLPGPRGQLGPEGDEGPMG---PPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPGP 989 Query: 595 VAVHG------VAIEDAVQGVANEDAVHG---VANEDAAQGIAKEVTAHGVANEDAVQGV 645 V G + E + G + + G V + G G E QG Sbjct: 990 VGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGP 1049 Query: 646 VNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVA 705 G+ A+ P G A E + G+ QG QG+A E Sbjct: 1050 PGSRGPPGM----RGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERG 1105 Query: 706 AHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVAN 765 G + G + +G+ E QG G G E + G A Sbjct: 1106 HLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAG 1165 Query: 766 EDVVQGVANEVEVQGIAHEDAVQGIANE------DAAHGIANEVAAHGVANEDAAQGVAN 819 G QG+ + G+ + D G + G E +G+ Sbjct: 1166 MKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMG 1225 Query: 820 EDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTN------EDAVQGVVNEEALHGVVA 873 ED G V G + QG A G E V G G Sbjct: 1226 EDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKG 1285 Query: 874 NEDAAQAIAKPDAAHGIANEGVANEVAAQGIAT------------EDVADGIAKDAA--- 918 + + P G+A +GI E DG A+ Sbjct: 1286 SRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPP 1345 Query: 919 --------HGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEV 970 G E Q+ + + QG G ++G Sbjct: 1346 GDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPK 1405 Query: 971 AAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIA 1030 QG A G VQG+ +G+ + ++GIA D G G A Sbjct: 1406 GKQGKA------GAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPG------RDGQA 1453 Query: 1031 NEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQ 1090 + QG + G A + G++ QG G+ + G + Sbjct: 1454 GQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRT 1513 Query: 1091 GIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANED 1150 G+ G G + E G+A +G ++ +G+ G+ ++ Sbjct: 1514 GLPGNQGEPG---SKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKE 1570 Query: 1151 AAHGIANEVAAHGIANEDAAQGIANEDAAQG 1181 G + G+ +G + QG Sbjct: 1571 GIVGPLGILGPSGLPGPKGDKGSRGDWGLQG 1601 Score = 61.2 bits (147), Expect = 1e-08 Identities = 108/583 (18%), Positives = 157/583 (26%), Gaps = 41/583 (7%) Query: 72 DAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGV 131 D V+G + G E G V G+ E +G+ + GV G Sbjct: 975 DGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGM---MGPPGVPGPKGSMGH 1031 Query: 132 ANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAA 191 G E QG G+ +G D A E ++ + Sbjct: 1032 PGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGP---AGEQGSRGLKGPPGP 1088 Query: 192 QGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHE 251 QG QG+A E G + G + +G+ E QG + G Sbjct: 1089 QGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGP 1148 Query: 252 DAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHE------DAVQGIANE 305 G E G G QG+ + G+ + D ++G + Sbjct: 1149 KGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGD 1208 Query: 306 DAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGV 365 G E G+ ED P G+ +G + + G A G Sbjct: 1209 PGPDGEHGEKGQEGLMGEDG------PPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGY 1262 Query: 366 AKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDA 425 ++ GV + G G + P A G G+A D Sbjct: 1263 QGQLGEMGVPGDPGPPGTPGPKGSRGSLG----------PTGAPGRMGAQGEPGLAGYDG 1312 Query: 426 AQGIANEVAAHGISKEDAVQG----IANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVH 481 +GI + G E QG G +G E G ++ V Sbjct: 1313 HKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQ 1372 Query: 482 GVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEV 541 G+ + G P ++G QG A G V G+ Sbjct: 1373 GLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKA------GAPGRRGVQGLQGLP 1426 Query: 542 AAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVA 601 GV IA PD G + QG E DG G V G+ Sbjct: 1427 GPRGVVGRQGLEGIAGPDGLPGRDGQAGQQG---EQGDDGDPGPMGPAGKRGNPGVAGLP 1483 Query: 602 IEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQG 644 G E + G +G G E +G Sbjct: 1484 GAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKG 1526 Score = 58.9 bits (141), Expect = 6e-08 Identities = 141/827 (17%), Positives = 228/827 (27%), Gaps = 68/827 (8%) Query: 67 GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHG---VANEDAAQGVANEVAAQGVA 123 G+ E G+ G+ G+ ++ G +G+ V G+ Sbjct: 793 GVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLK 852 Query: 124 NEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQ 183 + QGV G + QG+ A G + G + + + Sbjct: 853 GDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARG---KPGPLGKVGDKGSIGFPGPPGPE 909 Query: 184 DIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEV 243 + G ++ +G+ + A+G+ G ++ G ++G Sbjct: 910 GFPGDIGPPG---DNGPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRK 966 Query: 244 EVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIA 303 G D V+G + G E G GI E +G+ V G Sbjct: 967 GFPGRPGLDGVKGEPGDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPK 1026 Query: 304 NEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAH 363 G+ + G P G +G DG A E + Sbjct: 1027 GSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRG------PDGPAGEQGSR 1080 Query: 364 GVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANE 423 G+ G QGV E G I P G G+ E Sbjct: 1081 GLKGPPGPQGRPGRPGQQGVAGERGHLG----SRGFPGIPGPSGPPG------TKGLPGE 1130 Query: 424 DAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGV 483 QG + G G E G A G QG+ + G+ Sbjct: 1131 PGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGL 1190 Query: 484 AKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAA 543 + G PD G E +G+ ED G V G + Sbjct: 1191 EGDSGPMGPDGLKGDRGDPGPDGEHG---EKGQEGLMGEDGPPGPPGVTGVRGPEGKSGK 1247 Query: 544 HGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIE 603 G A A G ++ G+ + G + G G Sbjct: 1248 QGEKGRTGA------KGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGA 1301 Query: 604 DAVQGVANEDAVHGVA---------NEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGV 654 G+A D G+ E QG ++ A G +G V + G Sbjct: 1302 QGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQG--EDGKAEGPPGPPGDRGPVGDRGDRGE 1359 Query: 655 VAN-----EDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGI 709 + ++ Q + G G ++G QG A G Sbjct: 1360 PGDPGYPGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRG- 1418 Query: 710 SKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVV 769 VQG+ +G+ ++GIA D + G G A + QG + Sbjct: 1419 -----VQGLQGLPGPRGVVGRQGLEGIAGPDGLPG------RDGQAGQQGEQGDDGDPGP 1467 Query: 770 QGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAA------QGVANEDAA 823 G A + G+A QG G+ ++ G + QG Sbjct: 1468 MGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQ 1527 Query: 824 QGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHG 870 G + E G+A +G ++ G+ G++ +E + G Sbjct: 1528 PGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVG 1574 Score = 46.2 bits (108), Expect = 4e-04 Identities = 82/495 (16%), Positives = 139/495 (28%), Gaps = 33/495 (6%) Query: 1798 PDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQG 1857 P +RG G+ D G+P G G+ E G+ G Sbjct: 752 PKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELG 811 Query: 1858 IAKEDPIQGVANEVEVQG---VAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAN 1914 + + G+ ++ V G ++G+ G+ + QG+ Sbjct: 812 LPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQG 871 Query: 1915 EDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQG 1974 + +QG+ G + G + G +G ++ G ++ +G Sbjct: 872 DKGSQGLP---GFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPG---DNGPEG 925 Query: 1975 IANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDV 2034 + + A+G+ G ++ G P A G+ + +G Sbjct: 926 MKGKPGARGLPGPRGQLGPEGDEGPMG------------PPGAPGLEGQPGRKGFPGRPG 973 Query: 2035 ADGIANEDAAHGVANEDAAQAIAKPDAAHGIANE-GIATEDVADGIAEDAVQGITNEEAA 2093 DG+ E G Q G+ E GI E G+ G+ + + Sbjct: 974 LDGVKGEPGDPGRPGPVGEQGFM---GFIGLVGEPGIVGEKGDRGMM--GPPGVPGPKGS 1028 Query: 2094 QAIAKQDAAHGITKEDAAQGVTNEVA------AQGVANEDAAHGVANEVAAHGVANEDAA 2147 G E QG A+G G A E + G+ Sbjct: 1029 MGHPGMPGGMGTPGEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGP 1088 Query: 2148 QGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANE 2207 QG QGVA E G + G + +G+ E QG + G Sbjct: 1089 QGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGP 1148 Query: 2208 DAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGI 2267 G E G A G G+ + + + G G Sbjct: 1149 KGPPGAVGEPGLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGD 1208 Query: 2268 ANEDAVHGIANEDAV 2282 D HG ++ + Sbjct: 1209 PGPDGEHGEKGQEGL 1223 Score = 45.8 bits (107), Expect = 5e-04 Identities = 69/400 (17%), Positives = 120/400 (30%), Gaps = 30/400 (7%) Query: 56 DIANEDADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVAN 115 D + D HG ++ + G GV G + + G A+G Sbjct: 1205 DRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQG 1264 Query: 116 EVAAQGVANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQD 175 ++ GV + G +G G G+A D +GI Sbjct: 1265 QLGEMGVPGDPGPPGTPGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPG 1324 Query: 176 IAKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDA 235 E Q + A+G +G + +G E G ++ VQG+ + Sbjct: 1325 PKGEKGEQ--GEDGKAEGPPGPPGDRGPVGDRGDRG---EPGDPGYPGQEGVQGLRGKPG 1379 Query: 236 VQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAH 295 QG +G G A G + G QG+ +G+ Sbjct: 1380 QQGQPGHPGPRG------WPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVG 1433 Query: 296 EDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADG 355 ++GIA D + G + G +D + G A + G Sbjct: 1434 RQGLEGIAGPDGLPGRDGQAGQQGEQGDD---------------GDPGPMGPAGKRGNPG 1478 Query: 356 IANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEV 415 +A A G G+ + G + G+ N+ + +P G + E+ Sbjct: 1479 VAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGRTGLPGNQGEPGSKGQP----GDSGEM 1534 Query: 416 AAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG 455 G+A +G ++ GI G+ ++ G Sbjct: 1535 GFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVG 1574 >gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] Length = 1669 Score = 68.9 bits (167), Expect = 5e-11 Identities = 109/585 (18%), Positives = 166/585 (28%), Gaps = 19/585 (3%) Query: 956 GVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEV-----QGIAHKDAIQG 1010 G G+ ++ G +G+ VQG E V +G+ I G Sbjct: 693 GPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPG 752 Query: 1011 IANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDA 1070 E + G+ HG QGI E G+ V + G+ G Sbjct: 753 TPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGV-PGIGPPGARGPPG 811 Query: 1071 AQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVAN 1130 QG GI E G D + G + A G+ G+ QG Sbjct: 812 GQGPPGLSGPPGIKGEKGFPGFPGLD-MPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPG 870 Query: 1131 EVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQG 1190 G E V G + + G V A G+ E G +G +G Sbjct: 871 IPGFPGSKGEMGVMGTPGQPGSPG---PVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKG 927 Query: 1191 IANEDAVHGVAKEV---AAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIAN 1247 G +V + G + P +G + G+ +D G Sbjct: 928 DVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPG 987 Query: 1248 EDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQG 1307 + G G +G G E V GI + G+ + +G Sbjct: 988 QPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKG 1047 Query: 1308 VANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDA 1367 + G+ + G+ E QGIA + G E + GI + + Sbjct: 1048 EKGQAGPPGIG----IPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPG 1103 Query: 1368 AQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIAN 1427 + G + G + G+ V+G A G +G D + G A Sbjct: 1104 SVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAG 1163 Query: 1428 EDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHG 1487 E G+ G +G E G+A + G E G G Sbjct: 1164 EKGEPGLPGR-GFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPG 1222 Query: 1488 VANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHG 1532 + HA P RG + G+ G+ D G Sbjct: 1223 LPG-SPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKG 1266 Score = 64.3 bits (155), Expect = 1e-09 Identities = 143/803 (17%), Positives = 227/803 (28%), Gaps = 84/803 (10%) Query: 742 VHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEV-----QGIAHEDAVQGIANEDAA 796 V G+ ++ G G+ VQG E V +G+ + G E + Sbjct: 700 VDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGS 759 Query: 797 HGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNE 856 G+ HG QG+ E G+ GV G G Sbjct: 760 IGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPG-IGPPGARGPPGGQGPPGL 818 Query: 857 DAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKD 916 G+ E+ G G+ G + AQG+ Sbjct: 819 SGPPGIKGEKGFPGF----------------PGLDMPGPKGDKGAQGLP----------- 851 Query: 917 AAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVA 976 GIT + + Q A I ++G GV G V A G+ Sbjct: 852 ---GITGQSGLPGLPGQQGAPGIPGFPGSKG------EMGVMGTPGQPGSPGPVGAPGLP 902 Query: 977 NEDAVHGV------ANEDAVQGVANEVEVQG------IAHKDAIQGIANEDAAHGIANEV 1024 E HG + ++G +V + G +++G + G + Sbjct: 903 GEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPI 962 Query: 1025 AAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIA 1084 G + G+ +D G + G G +G G Sbjct: 963 GEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTP 1022 Query: 1085 HEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQ 1144 E V GI G+ + A G + G+ + G+ E QG+A Sbjct: 1023 GEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGI----GIPGLRGEKGDQGIAGFPGSP 1078 Query: 1145 GIANEDAAHGIANEVAAHGIANE------DAAQGIANEDAAQGIAHEDAVQGIANEDAVH 1198 G E + GI + G+ + G+ E +G+ D + G+ E + Sbjct: 1079 GEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLP 1138 Query: 1199 GVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEV 1258 G G E + D G A E G+ G G EV Sbjct: 1139 GTPGPTGPAGQKGEPGS------DGIPGSAGEKGEPGLPGRGF-PGFPGAKGDKGSKGEV 1191 Query: 1259 AAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPV--QGVANEDPIQG 1316 G++ + G E QG QG + G A E P +G + + G Sbjct: 1192 GFPGLAGSPGIPGSKGE---QGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPG 1248 Query: 1317 VANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDA 1376 + + G+ D V+G + G G + Q + + GI+ Sbjct: 1249 LPGPMGPPGLPGIDGVKG---DKGNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKG 1305 Query: 1377 VQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIAN 1436 G QG +QG+ + QGV + G I + G+ Sbjct: 1306 DMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEP--GLPG 1363 Query: 1437 EVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHA 1496 G+ G + G+ GI D G E+ G A Sbjct: 1364 PEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEM---GPAGPTGPRG 1420 Query: 1497 IAKPDAARGIANEVATQGIATED 1519 P G+ + G + D Sbjct: 1421 FPGPPGPDGLPGSMGPPGTPSVD 1443 Score = 63.2 bits (152), Expect = 3e-09 Identities = 136/764 (17%), Positives = 218/764 (28%), Gaps = 62/764 (8%) Query: 690 GIANEDAAQGIANEVAAHGISKEDAVQGIANEDAA-----QGIAHEDAVQGIANEDAVHG 744 G+ + G +G+ VQG E +G+ + G E G Sbjct: 702 GLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIG 761 Query: 745 VAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVA 804 V HG +QG+ E G+ V G V GI G Sbjct: 762 VPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPG------VPGI----GPPGARGPPG 811 Query: 805 AHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVN 864 G G+ E G D + G + AQG+ G+T + + G+ Sbjct: 812 GQGPPGLSGPPGIKGEKGFPGFPGLD-MPGPKGDKGAQGLP------GITGQSGLPGLPG 864 Query: 865 EEALHGV---VANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAA--- 918 ++ G+ ++ + P G V A G+ E G + Sbjct: 865 QQGAPGIPGFPGSKGEMGVMGTP------GQPGSPGPVGAPGLPGEKGDHGFPGSSGPRG 918 Query: 919 -HGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVAN 977 G+ ++ + + + + + +G + G +G + GV Sbjct: 919 DPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPG 978 Query: 978 EDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQG 1037 +D G + +G G +G G E GI + G Sbjct: 979 KDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPG 1038 Query: 1038 IANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHED---AVQGIAN 1094 + + A+G + GI + G+ E QGIA + G E + G+ Sbjct: 1039 LPGDKGAKGEKGQAGPPGI----GIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPG 1094 Query: 1095 EDAVHGVAKEV---AAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDA 1151 + G V + G+ E +G+ D + GV E + G G E Sbjct: 1095 SPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPG 1154 Query: 1152 AHGIANEVAAH-----------GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1200 + GI G +G E G+A + G E G Sbjct: 1155 SDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGP 1214 Query: 1201 AKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAA 1260 G+ HA P RG + G+ G+ D GV + Sbjct: 1215 PGPQGQPGLPG-SPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGID---GVKGDKGN 1270 Query: 1261 HGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANE 1320 G V G + QG+ GI G QG +QG+ + Sbjct: 1271 PGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGD 1330 Query: 1321 VEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGI 1380 QGV + G + I + G+ + + G + V G+ Sbjct: 1331 QGDQGVPGAKGLPGPPGPPGPYDIIKGE--PGLPGPEGPPGLKGLQGLPGPKGQQGVTGL 1388 Query: 1381 ANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQG 1424 GI D G E G G D + G Sbjct: 1389 VGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPG 1432 Score = 57.4 bits (137), Expect = 2e-07 Identities = 119/688 (17%), Positives = 198/688 (28%), Gaps = 42/688 (6%) Query: 672 GIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHED 731 G+ HG QGI E G+ V + G V GI A+G Sbjct: 761 GVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPG------VPGI-GPPGARGPPGGQ 813 Query: 732 AVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIA 791 G++ + G G+ P +G + G+ + + G+ + GI Sbjct: 814 GPPGLSGPPGIKGEKGFPGFPGLDMPGP-KGDKGAQGLPGITGQSGLPGLPGQQGAPGIP 872 Query: 792 NEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAH 851 + G E+ G + + G A G+ E HG +G Sbjct: 873 GFPGSKG---EMGVMGTPGQPGSPGPV---GAPGLPGEKGDHGFPGSSGPRG-------- 918 Query: 852 GVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVAD 911 + ++G + L G + D + +G + +G + Sbjct: 919 ----DPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTP 974 Query: 912 GI-AKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEV 970 G+ KD G + + +G G E G+ Sbjct: 975 GVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQ 1034 Query: 971 AAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIA 1030 + G+ + G + G+ + G+ + QGIA + G E + GI Sbjct: 1035 GSPGLPGDKGAKGEKGQAGPPGIG----IPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIP 1090 Query: 1031 NEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQ 1090 + G+ + G G + + G+ +G A G + Sbjct: 1091 GMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQK 1150 Query: 1091 GIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANED 1150 G D + G A E G+ G +G EV G+A + G E Sbjct: 1151 GEPGSDGIPGSAGEKGEPGLPGRG-FPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQ 1209 Query: 1151 AAHGIANEVAAHGIANE--DAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHG 1208 G G+ A +G + QG + G + G+ G Sbjct: 1210 GFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKG 1269 Query: 1209 VANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDA 1268 A + P G QG+ + GI G G Sbjct: 1270 NPGWPGAPGVPGPKGDPGF------QGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPG 1323 Query: 1269 VQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAH 1328 +QGI + QG+ + G I K +P G+ + G+ + G Sbjct: 1324 LQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGEP--GLPGPEGPPGLKGLQGLPGPKG 1381 Query: 1329 EDAVQGIANEDAAHGIANEDAAQGIANE 1356 + V G+ GI D A G E Sbjct: 1382 QQGVTGLVGIPGPPGIPGFDGAPGQKGE 1409 Score = 53.9 bits (128), Expect = 2e-06 Identities = 80/423 (18%), Positives = 131/423 (30%), Gaps = 30/423 (7%) Query: 1821 GIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHED 1880 G P E + GV HG +QGI E G+ GV + G Sbjct: 752 GTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPG-IGPPGARGPP 810 Query: 1881 AVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDA--AQGISKEDAVQGIANQDAAQG 1938 QG GI E G D ++ A GI+ + + G+ Q A G Sbjct: 811 GGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPG 870 Query: 1939 I------AKEDAVQGIANED------AAQGIANEVAAHGIANEDAAQ---GIANEDAAQG 1983 I E V G + A G+ E HG + G+ + G Sbjct: 871 IPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVG 930 Query: 1984 IAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDA 2043 + + + ++ G + P +G + G+ +D G + Sbjct: 931 LPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPG 990 Query: 2044 AH---GVANEDAAQAIAKP-DAAHGIANEGIATEDVADGI-AEDAVQGITNEEAAQAIAK 2098 G++ A + P + G+ G E GI G+ ++ A+ Sbjct: 991 PKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKG 1050 Query: 2099 QDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQG 2158 Q GI G+ E QG+A + G E + G+ + G+ + G Sbjct: 1051 QAGPPGI----GIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVG 1106 Query: 2159 VANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVA 2218 + G + +G+ D I G+ E G G E + G+ Sbjct: 1107 YPGSPGLPGEKGD---KGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAG 1163 Query: 2219 AQG 2221 +G Sbjct: 1164 EKG 1166 Score = 52.0 bits (123), Expect = 7e-06 Identities = 122/672 (18%), Positives = 184/672 (27%), Gaps = 56/672 (8%) Query: 1600 PDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAA-----HGISKEDAVQGIANE 1654 P G+ ++ + G+ QG E G+ + G E Sbjct: 697 PKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGE 756 Query: 1655 DAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPV--------QGVA 1706 + G+ G +QGI E G+ V + GV P QG Sbjct: 757 KGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPP 816 Query: 1707 NEDAVQGVANEVEVQGVAHED--AVQGIANEDAAHGITNEVAAHGIANEDAAQGIAH--- 1761 G+ E G D +G GIT + G+ + A GI Sbjct: 817 GLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPG 876 Query: 1762 EDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADG 1821 G+ V A G+ E H RG + +G + G Sbjct: 877 SKGEMGVMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRG---DPGLKGDKGDVGLPG 933 Query: 1822 IPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDA 1881 P + + G E G E ++G + G + G Sbjct: 934 KPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKG 993 Query: 1882 VQGIANEDAAHGIANEDAA------QGIANEDAAQDIANEDAAQGISKEDAVQGIANQDA 1935 GI+ A G+ + G E I + G+ + +G Q Sbjct: 994 DPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAG 1053 Query: 1936 AQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIAN 1995 GI + G+ E QGIA + G E + GI + G+ G Sbjct: 1054 PPGIG----IPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPG 1109 Query: 1996 EDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQA 2055 G+ E + D G+ E G G E + G+ Sbjct: 1110 SP---GLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGS----- 1161 Query: 2056 IAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVT 2115 A G+ G A G +G E +A + GI QG Sbjct: 1162 -AGEKGEPGLPGRGFPGFPGAKGD-----KGSKGEVGFPGLA---GSPGIPGSKGEQGFM 1212 Query: 2116 NEVAAQGVANEDAAHGVANE--VAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVE 2173 QG + G A E G + G+ + G+ D V+G Sbjct: 1213 GPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPG 1272 Query: 2174 ------VQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDA 2227 V G QG+ + G+ G QG QG+ + Sbjct: 1273 WPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQG 1332 Query: 2228 AQGVANEVAVHG 2239 QGV + G Sbjct: 1333 DQGVPGAKGLPG 1344 Score = 49.3 bits (116), Expect = 5e-05 Identities = 109/628 (17%), Positives = 167/628 (26%), Gaps = 60/628 (9%) Query: 1623 GIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 1682 GI Q G+ + A GI G G+ G G+ E Sbjct: 852 GITGQSGLPGLPGQQGAPGIP------GFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEK 905 Query: 1683 AVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIT 1742 HG G DP G+ + G+ + +++G + G Sbjct: 906 GDHGFPGSSGPRG----DP--GLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQI 959 Query: 1743 NEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAA- 1801 + G + G+ +D G + G++ A + P + Sbjct: 960 GPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDP------GISGTPGAPGLPGPKGSV 1013 Query: 1802 -----RGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQ 1856 G E GI + G+P + A G + GI + G+ E Q Sbjct: 1014 GGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIG----IPGLRGEKGDQ 1069 Query: 1857 GIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANED 1916 GIA G E G+ G+ + G + G+ E + + D Sbjct: 1070 GIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPG---SPGLPGEKGDKGLPGLD 1126 Query: 1917 AAQGISKEDAVQGIANQDAAQGIAKE---DAVQGIANEDAAQGIANEVAAHGIANEDAAQ 1973 G+ E + G G E D + G A E G+ G + Sbjct: 1127 GIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGR-GFPGFPGAKGDK 1185 Query: 1974 GIANEDAAQGIAHEDAVQGIANEDAVHGVANEDA--------AHAIAKPDAARGIANEVA 2025 G E G+A + G E G HA P RG + Sbjct: 1186 GSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGDRGPQGQPG 1245 Query: 2026 AQGIATEDVADGIANEDAAHGVANEDA---AQAIAKPDAAHGIANEGIATEDVADGIAED 2082 G+ G+ D G A + P G GI Sbjct: 1246 LPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQG--------MPGIGGS 1297 Query: 2083 AVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVA 2142 GIT + G QG+ + QGV G + + Sbjct: 1298 P--GITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDII 1355 Query: 2143 NEDAA----QGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANE 2198 + +G QG+ QGV V + G G + G A Sbjct: 1356 KGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGP 1415 Query: 2199 VAAHGVANEDAAQGVANEVAAQGVANED 2226 G G+ + G + D Sbjct: 1416 TGPRGFPGPPGPDGLPGSMGPPGTPSVD 1443 Score = 46.6 bits (109), Expect = 3e-04 Identities = 138/791 (17%), Positives = 211/791 (26%), Gaps = 81/791 (10%) Query: 74 VQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVAN 133 ++G+ G E + GV HG QG+ E G+ GV Sbjct: 741 LKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPG 800 Query: 134 EDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQG 193 G QG GI E G D + A G Sbjct: 801 -IGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGA-------QGLPG 852 Query: 194 ISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDA 253 I+ + + G+ + A GI G GV G V G+ E Sbjct: 853 ITGQSGLPGLPGQQGAPGI------PGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKG 906 Query: 254 VQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAK 313 G G G+ + G+ + + +++G + G Sbjct: 907 DHGFPGSSGPRG------DPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIG 960 Query: 314 EVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKEVTAHG 373 + G + + D G + +G GI+ A G+ Sbjct: 961 PIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKG------DPGISGTPGAPGL-------- 1006 Query: 374 VANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEV 433 +G V L G E I P + G+ + A G + GI Sbjct: 1007 ----PGPKGSVGGMGLPG-TPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGI---- 1057 Query: 434 AAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVA 493 + G+ E QGIA + G E GI G+ Sbjct: 1058 ---------GIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGL---------- 1098 Query: 494 NKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAH 553 K + ++ P + G+ E +G+ D G+ E + G G E + Sbjct: 1099 -KGSPGSVGYP-GSPGLPGEKGDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGS- 1155 Query: 554 AIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANED 613 D G A E G+ G G EV G+A + G E Sbjct: 1156 -----DGIPGSAGEKGEPGLPGRGF-PGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQ 1209 Query: 614 AVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVA-----NEDAAQAIAKPD 668 G G+ H +G + L G+ + Sbjct: 1210 GFMGPPGPQGQPGLPGS-PGHATEGPKGDRGPQGQPGLPGLPGPMGPPGLPGIDGVKGDK 1268 Query: 669 AAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIA 728 G G + QG+ + GI G QG QGI Sbjct: 1269 GNPGWPGAPGVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIK 1328 Query: 729 HEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQ 788 + QG+ + G + + +P G+ + G+ + G + V Sbjct: 1329 GDQGDQGVPGAKGLPGPPGPPGPYDIIKGEP--GLPGPEGPPGLKGLQGLPGPKGQQGVT 1386 Query: 789 GIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKE- 847 G+ GI A G E G G D + G V Sbjct: 1387 GLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGLPGSMGPPGTPSVDHGF 1446 Query: 848 -VTAHGVTNED 857 VT H T +D Sbjct: 1447 LVTRHSQTIDD 1457 Score = 46.2 bits (108), Expect = 4e-04 Identities = 196/1099 (17%), Positives = 297/1099 (27%), Gaps = 100/1099 (9%) Query: 946 QGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVAN-----EVEVQ 1000 QG + GV+ G A +V +G G E QG+ E Sbjct: 225 QGPKGDKGDQGVSGPPGVPGQA-QVQEKGDFATKGEKGQKGEPGFQGMPGVGEKGEPGKP 283 Query: 1001 GIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKED 1060 G K G E + G E G+ QG E G V G E Sbjct: 284 GPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLGEK 343 Query: 1061 AVQGIANEDAAQGIANEDAAQGIAHEDA-----VQGIANEDAVHGVAKEVAAHGVANEDP 1115 +G +G G+ + V G A G E G Sbjct: 344 GERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTS- 402 Query: 1116 VQGVANEDAVQGVANEVEVQGVAHE-----DAVQGIANEDAAHGIANEVAAHGIANEDAA 1170 + G + D + G G + G + GI + G E Sbjct: 403 LPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQ 462 Query: 1171 QG----IANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARG 1226 +G I + D +G QG E G G+ D + P G Sbjct: 463 KGESCLICDIDGYRG---PPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPG 519 Query: 1227 IANEVAAQGIATEDVAD-------GIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQ 1279 + + A+G E D G G+ + G + G + Sbjct: 520 LIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSV 579 Query: 1280 GIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANED 1339 G+ E G ++G G PI G + G + G E Sbjct: 580 GLKGERGPPGGVGFPGSRGDTGPPGPPGYGPAGPI-GDKGQAGFPGGPGSPGLPGPKGEP 638 Query: 1340 AAH-GIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDP---- 1394 + A+G+ + G + G GI P Sbjct: 639 GKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPK 698 Query: 1395 -VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAA-----HGIANEVAAHGIANEDA 1448 V G+ + G G+ VQG E G+ G E Sbjct: 699 GVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGEKG 758 Query: 1449 AQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIAN 1508 + G+ G +QGI E G+ V + GV A P +G Sbjct: 759 SIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGIGPPGARGPP-GGQGPPG 817 Query: 1509 EVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHG 1568 GI E G D G + AQG+ G+ + + G+ + A G Sbjct: 818 LSGPPGIKGEKGFPGFPGLDMP-GPKGDKGAQGLP------GITGQSGLPGLPGQQGAPG 870 Query: 1569 VANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQD 1628 + +G + V P A G+ E H +G Sbjct: 871 IPGFPGSKGEMG-------VMGTPGQPGSPGPVGAPGLPGEKGDHGFPGSSGPRGDPGLK 923 Query: 1629 AAQGIANEVAAHG-ISKED--AVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVH 1685 +G G + K D +++G + +G +G + G+ +D Sbjct: 924 GDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQA 983 Query: 1686 GVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEV 1745 G + G G +G + + G E V GI + G+ + Sbjct: 984 GQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDK 1043 Query: 1746 AAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIA 1805 A G + GI + G+ E K D +GIA Sbjct: 1044 GAKGEKGQAGPPGIG----IPGLRGE-------------------------KGD--QGIA 1072 Query: 1806 NEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQ 1865 + G E + GIP + G+ + G G+ E +G+ D I Sbjct: 1073 GFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGY---PGSPGLPGEKGDKGLPGLDGIP 1129 Query: 1866 GVANEVEVQGVAHEDAVQGIANEDAAHGI---ANEDAAQGIANEDAAQDIANEDAAQGIS 1922 GV E + G G E + GI A E G+ +G Sbjct: 1130 GVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGR-GFPGFPGAKGDKGSK 1188 Query: 1923 KEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQ 1982 E G+A G E G G+ H +G + Sbjct: 1189 GEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGS-PGHATEGPKGDRGPQGQPGLP 1247 Query: 1983 GIAHEDAVQGIANEDAVHG 2001 G+ G+ D V G Sbjct: 1248 GLPGPMGPPGLPGIDGVKG 1266 Score = 35.0 bits (79), Expect = 0.88 Identities = 82/429 (19%), Positives = 115/429 (26%), Gaps = 73/429 (17%) Query: 67 GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126 G+ E QG+A + G E + G+ + G+ + G + G+ E Sbjct: 1061 GLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPG---SPGLPGEK 1117 Query: 127 AVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGI---ANEDAAQDI------- 176 +G+ D + GV E + G G E + GI A E + Sbjct: 1118 GDKGLPGLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPG 1177 Query: 177 ---AKED-------------AAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPV-- 218 AK D + I QG QG + G A E P Sbjct: 1178 FPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGHATEGPKGD 1237 Query: 219 ---------------QGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAA 263 G + GV + G V G + QG+ + Sbjct: 1238 RGPQGQPGLPGLPGPMGPPGLPGIDGVKGDKGNPGWPGAPGVPGPKGDPGFQGMPGIGGS 1297 Query: 264 HGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANE-------------DAVHG 310 GIT G QG QGI + QG+ D + G Sbjct: 1298 PGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKG 1357 Query: 311 VAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKEVT 370 G + P G+ V G GI D A G E+ Sbjct: 1358 EPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPG------PPGIPGFDGAPGQKGEMG 1411 Query: 371 AHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIA 430 G G D L G + P HG V H +D Sbjct: 1412 PAGPTGPRGFPGPPGPDGLPGSMGPP------GTPSVDHGFL--VTRHSQTIDDPQCPSG 1463 Query: 431 NEVAAHGIS 439 ++ HG S Sbjct: 1464 TKILYHGYS 1472 >gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] Length = 1626 Score = 63.9 bits (154), Expect = 2e-09 Identities = 179/1031 (17%), Positives = 288/1031 (27%), Gaps = 57/1031 (5%) Query: 1225 RGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKE 1284 RG E+ G+ E G G V A G+ E +G E +G+ Sbjct: 550 RGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGL--- 606 Query: 1285 DAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGI 1344 D G + QG V G E G A V G + +G+ E A G Sbjct: 607 DGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQ--EGLKGEQGAPGP 664 Query: 1345 ANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAV 1404 A G D G+ ++G + GI +QG V Sbjct: 665 RGHQGAPGPPGARGPIGPEGRDGPPGLQ---GLRGKKGDMGPPGIPGLLGLQGPPGPPGV 721 Query: 1405 QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHE 1464 G G+ E G G + +G +G E G+ + Sbjct: 722 PGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGK 781 Query: 1465 DAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGI 1524 ++G E + G E G+ + +G E+ G+ + G Sbjct: 782 PGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGE 841 Query: 1525 ANEDAAHGVANEVAA----------QGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDA 1574 A G+ + QG E G+ E +QG E+ G Sbjct: 842 AGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPG 901 Query: 1575 VQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIA 1634 +G N A + P + G V A + G + A G Sbjct: 902 AKGQEGAHGAPGAAGNPGAPGHVGAPGPS-GPPGSVGAPGLRGTPGKDGERGEKGAAGEE 960 Query: 1635 NEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAK--EVA 1692 G + G+ +D G+ + G A G + E Sbjct: 961 GSPGPVGPRGDPGAPGLPGPPGK----GKDGEPGLRGSPGLPGPLGTKAACGKVRGSENC 1016 Query: 1693 AHG---VANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHG 1749 A G V + G+ +G + V G G + G+ G Sbjct: 1017 ALGGQCVKGDRGAPGIPGSPGSRGDPG-IGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQG 1075 Query: 1750 IANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVA 1809 A D A G E +G + + S+ + +A + P G+ Sbjct: 1076 PAGRDGAPGNPGE---RGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKG 1132 Query: 1810 AQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVAN 1869 +G+ G P + G E G+ GIA +QG +G Sbjct: 1133 DKGVP------GKPGREGTEGKKGEAGPPGLP---GPPGIAGPQGSQG------ERGADG 1177 Query: 1870 EVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQG 1929 EV +G V G G D G A Q ++ G + G Sbjct: 1178 EVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPG 1237 Query: 1930 IANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDA 1989 I ++ +G D G E G G +G + A G E Sbjct: 1238 IPGEEGKEG---RDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESG 1294 Query: 1990 VQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVAN 2049 G+ ++ + G + P RG + + G E G + + G Sbjct: 1295 AMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENG 1354 Query: 2050 EDAAQAIAKPDAAHGIANE-GIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKE 2108 P G E G+ ++ G + G E I G + Sbjct: 1355 SPGLPGFLGPRGPPGEPGEKGVPGKEGVPG--KPGEPGFKGERGDPGIKGDKGPPGGKGQ 1412 Query: 2109 DAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGV 2168 G+ G+ G V G + G+ E + + + Sbjct: 1413 PGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEEL 1472 Query: 2169 ANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAA 2228 ++E + +A+ A A ++QG G +D G A + G + Sbjct: 1473 GKQLETR-LAYLLAQMPPAYMKSSQG---RPGPPGPPGKDGLPGRAGPMGEPGRPGQGGL 1528 Query: 2229 QGVANEVAVHG 2239 +G + + G Sbjct: 1529 EGPSGPIGPKG 1539 Score = 62.4 bits (150), Expect = 5e-09 Identities = 142/794 (17%), Positives = 224/794 (28%), Gaps = 58/794 (7%) Query: 946 QGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHK 1005 QG G A+G G + G + G+ + +QG Sbjct: 659 QGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGP 718 Query: 1006 DAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGI 1065 + G + G+ E+ G G +D G G E G+ Sbjct: 719 PGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGL 778 Query: 1066 ANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAV 1125 + +G E G E G+ GV E G E + G+ + Sbjct: 779 PGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGE 838 Query: 1126 QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHE 1185 +G A G A + G + H G E G+ E QG E Sbjct: 839 KGEA------GPAGPPGLPGTTSLFTPH--PRMPGEQGPKGEKGDPGLPGEPGLQGRPGE 890 Query: 1186 DAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGI 1245 QG G A G A A G V A G+ DG Sbjct: 891 LGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGE 950 Query: 1246 ANEDAAHGVANEVAAHGISKEDAVQGI-----ANEDAAQGIAKEDAVQGIANEDAAQGIA 1300 E A G G + G+ +D G+ + G AA G Sbjct: 951 RGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKV 1010 Query: 1301 KEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQ 1360 + + Q V + G+ +G D G+A G + + Sbjct: 1011 RGSENCALGG----QCVKGDRGAPGIPGSPGSRG----DPGIGVAGPPGPSGPPGDKGS- 1061 Query: 1361 DIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHE- 1419 ++G+ QG A D A G E +G + + + + ++ +A + Sbjct: 1062 -----PGSRGLPGFPGPQGPAGRDGAPGNPGE---RGPPGKPGLSSLLSPGDINLLAKDV 1113 Query: 1420 --DAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVH 1477 D G G + G + +G E G+ + G Sbjct: 1114 CNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGER 1173 Query: 1478 GVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEV 1537 G EV G D H G+ + G ADGIA G A Sbjct: 1174 GADGEVGQKG----DQGHP--------GVPGFMGPPGNPGPPGADGIA------GAAGPP 1215 Query: 1538 AAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAI 1597 QG + G + G+ E G + G + + E A Sbjct: 1216 GIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGA---- 1271 Query: 1598 AKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAA 1657 P G + A + A G+ Q+ G + G +G ++ + Sbjct: 1272 RGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGS 1331 Query: 1658 QGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANE 1717 G E G + +G E+ G+ + G E +GV ++ V G E Sbjct: 1332 PGSPGEPGPSGTPGQ---KGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGE 1388 Query: 1718 VEVQGVAHEDAVQG 1731 +G + ++G Sbjct: 1389 PGFKGERGDPGIKG 1402 Score = 61.6 bits (148), Expect = 9e-09 Identities = 159/876 (18%), Positives = 234/876 (26%), Gaps = 83/876 (9%) Query: 410 GIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHED 469 G+ EV G G V A G+ E +G E +G+ D G + Sbjct: 560 GLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGL---DGFPGKPGDT 616 Query: 470 AVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQ-GIATEDVADGI 528 QG V G E G P G+ V Q G+ E A G Sbjct: 617 GQQGRPGPSGVAGPQGEKGDVG------------PAGPPGVPGSVVQQEGLKGEQGAPGP 664 Query: 529 ANEDAVHGVANEVAAHGVANEDAAHAIA-----KPDAAH-GIANEVATQGIATEDVADGI 582 G G D + K D GI + QG G Sbjct: 665 RGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGP 724 Query: 583 ANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAV 642 + G+ E+ G G +D +G +G E G+ + + Sbjct: 725 PGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGL 784 Query: 643 QGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAN 702 +G + E L G + A P G+ E G E G+ + +G A Sbjct: 785 RGEIGEQGLAGRPGEKGEAGLPGAPGFP-GVRGEKGDQGEKGELGLPGLKGDRGEKGEAG 843 Query: 703 EVAAHGI-------------------SKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVH 743 G+ E G+ E QG E QG Sbjct: 844 PAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAK 903 Query: 744 GVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEV 803 G A G A G G V G+ G E A G Sbjct: 904 GQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSP 963 Query: 804 AAHGVANEDAAQGVAN-----EDAAQGVANEDAVHGVANEDAAQGVAK--EVTAHG---V 853 G + A G+ +D G+ + G AA G + E A G V Sbjct: 964 GPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCV 1023 Query: 854 TNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANE-------GVANEVAAQGIAT 906 + G+ G D +A P G + G+ QG A Sbjct: 1024 KGDRGAPGIPGSPGSRG-----DPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAG 1078 Query: 907 EDVADGI-------AKDAAHGITKEEAAQAIAKQ---DAAHSITNEDAAQGVANEDAAHG 956 D A G K + +AK D G + G Sbjct: 1079 RDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPG 1138 Query: 957 VANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDA 1016 + +G E G+ + G +G EV +G + G Sbjct: 1139 KPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPG 1198 Query: 1017 ------AHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDA 1070 A GIA GI +G G+ G D G E Sbjct: 1199 NPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPG 1258 Query: 1071 AQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVAN 1130 G +G +G + G E A G+ ++ + G + G Sbjct: 1259 KAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQG 1318 Query: 1131 EVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQG 1190 +G ++ G E G + + G E+ + G+ +G E +G Sbjct: 1319 PQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKG---ENGSPGLPGFLGPRGPPGEPGEKG 1375 Query: 1191 IANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARG 1226 + ++ V G E G + P +G Sbjct: 1376 VPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKG 1411 Score = 58.9 bits (141), Expect = 6e-08 Identities = 155/813 (19%), Positives = 231/813 (28%), Gaps = 84/813 (10%) Query: 76 GVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANED 135 G+ EV +G G V A G+ E +G E +G+ D G + Sbjct: 560 GLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGL---DGFPGKPGDT 616 Query: 136 AVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQGIS 195 QG V G E G A G + +++ + QG Sbjct: 617 GQQGRPGPSGVAGPQGEKGDVGPAGPPGVPG--------SVVQQEGLK------GEQGAP 662 Query: 196 KEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQ 255 QG A+G + G ++G + G+ + +QG V Sbjct: 663 GPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVP 722 Query: 256 GIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEV 315 G + G+ E+ G G +D G +G E G+ Sbjct: 723 GPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLP--- 779 Query: 316 AAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKEVTAHGVA 375 KP G+ E+ QG+A G A A G GV Sbjct: 780 --------------GKP----GLRGEIGEQGLAGRPGEKGEAGLPGAPGFP------GVR 815 Query: 376 NEDAVQGVVNEDALHGVVAN--EDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEV 433 E QG E L G+ + E A P G + H QG E Sbjct: 816 GEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPH--PRMPGEQGPKGEK 873 Query: 434 AAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVA 493 G+ E +QG E QG A+G G A G V A G + Sbjct: 874 GDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPG---HVGAPGPS 930 Query: 494 NKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAH 553 + G E +G A E+ + G G G + Sbjct: 931 GPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPG 990 Query: 554 AIAKPDAAHGIANEVATQGI-ATEDVADG---IANEDAAHGVANEVAVHGVAIEDAVQGV 609 P + + A + +E+ A G + + A G+ G D GV Sbjct: 991 LRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRG----DPGIGV 1046 Query: 610 ANEDAVHGVANEDAA---QGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAK 666 A G + + +G+ G A D G E G + ++ Sbjct: 1047 AGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPG----KPGLSSLLS 1102 Query: 667 PDAAHGIANEVAAH---------GIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQG 717 P + +A +V G+ +G+ + +G + G G Sbjct: 1103 PGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPG 1162 Query: 718 IANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVE 777 IA +QG D G + GV + G G+A G A Sbjct: 1163 IAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIA------GAAGPPG 1216 Query: 778 VQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVAN 837 +QG ++ G GI E G D G E G G Sbjct: 1217 IQGSPGKEGPPGPQGPSGLPGIPGE---EGKEGRDGKPGPPGEPGKAGEPGLPGPEGARG 1273 Query: 838 EDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHG 870 +G + A G E G+ +E L G Sbjct: 1274 PPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPG 1306 Score = 58.2 bits (139), Expect = 1e-07 Identities = 139/779 (17%), Positives = 205/779 (26%), Gaps = 36/779 (4%) Query: 75 QGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANE 134 QG QG A G G +G ++ G+ +QG Sbjct: 659 QGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGP 718 Query: 135 DAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQGI 194 V G G+ E G G +D + E G+ Sbjct: 719 PGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGL 778 Query: 195 SKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAV 254 + ++G E G E G+ GV E QG E+ + G+ + Sbjct: 779 PGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGE 838 Query: 255 QGIANEDAAHGITNEVA----------AHGIANEDAAQGIANEDAAQGIAHEDAVQGIAN 304 +G A G+ + G E G+ E QG E QG Sbjct: 839 KGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTG 898 Query: 305 EDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHG 364 G A G A A G V G+ DG E A G Sbjct: 899 PPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAG 958 Query: 365 VAKEVTAHGVANEDAVQGVV--------NEDALHGVVANEDAAQAIAKPDAAHGIAN-EV 415 G + G+ E L G A G N + Sbjct: 959 EEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCAL 1018 Query: 416 AAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIA 475 + + A GI + G V G G ++G+ QG A Sbjct: 1019 GGQCVKGDRGAPGIPGSPGSRG-DPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPA 1077 Query: 476 NEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVH 535 D G E G K ++ P +A +V G+ Sbjct: 1078 GRDGAPGNPGE---RGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDK 1134 Query: 536 GVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEV 595 GV + G + A P G QG E ADG E G Sbjct: 1135 GVPGKPGREGTEGKKGE---AGPPGLPGPPGIAGPQGSQGERGADG---EVGQKGDQGHP 1188 Query: 596 AVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVV 655 V G G D + G A QG + G + G+ E+ G Sbjct: 1189 GVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEG-- 1246 Query: 656 ANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAV 715 D G G +G + A G E A G+ + Sbjct: 1247 --RDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQ--- 1301 Query: 716 QGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANE 775 +G+ +D G QG +G G + +G E+ G+ Sbjct: 1302 EGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGF 1361 Query: 776 VEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHG 834 + +G E +G+ ++ G E G + +G +G + + G Sbjct: 1362 LGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPG 1420 Score = 55.1 bits (131), Expect = 8e-07 Identities = 161/878 (18%), Positives = 238/878 (27%), Gaps = 70/878 (7%) Query: 1408 ANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIA----NEDAAQGIAH 1463 A E GVA + G + A G V A G E GI E +G Sbjct: 480 AGEKGEMGVAGPMGLPGPKGDIGAIG---PVGAPGPKGEKGDVGIGPFGQGEKGEKGSLG 536 Query: 1464 EDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADG 1523 G + G E+ G+ E P G V G+ E G Sbjct: 537 LPGPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKG 596 Query: 1524 IANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQG-VVNED 1582 E G+ G + G + QG +V G A V G VV ++ Sbjct: 597 TRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDV---GPAGPPGVPGSVVQQE 653 Query: 1583 ALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGI 1642 L Q P G A + G +G ++ GI Sbjct: 654 GLKG-------EQGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGI 706 Query: 1643 SKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPV 1702 +QG G + G+ E G G + +G Sbjct: 707 PGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGT 766 Query: 1703 QGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHE 1762 +G E G+ + ++G E + G E G+ G+ E QG E Sbjct: 767 KGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGE 826 Query: 1763 DAVQGIANEDAVHSVAKEVAAHGVANEDAAHAI-AKPDAARGIANEVAAQGIATEDVADG 1821 + G+ + A G+ + + +G E G+ E G Sbjct: 827 LGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQG 886 Query: 1822 IPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDA 1881 P E G A G G A A G G V G+ Sbjct: 887 RPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPG 946 Query: 1882 VQGIANEDAAHGIANEDAAQGIANEDAAQDIAN-----EDAAQGISKEDAVQGIANQDAA 1936 G E A G G + A + +D G+ + G AA Sbjct: 947 KDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAA 1006 Query: 1937 QGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANE 1996 G + +E+ A G + + A GI ++G D G+A Sbjct: 1007 CGKVR-------GSENCALG------GQCVKGDRGAPGIPGSPGSRG----DPGIGVAGP 1049 Query: 1997 DAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAI 2056 G + + +RG+ QG A D A G E G + ++ Sbjct: 1050 PGPSGPPGDKGS------PGSRGLPGFPGPQGPAGRDGAPGNPGE---RGPPGKPGLSSL 1100 Query: 2057 AKPD----AAHGIANEGIATEDVADGI----AEDAVQGITNEEAAQAIAKQDAAHGITKE 2108 P A + N+ G+ + V G E + + G+ Sbjct: 1101 LSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLP-- 1158 Query: 2109 DAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGV 2168 G+ +QG G EV G G G D + G Sbjct: 1159 -GPPGIAGPQGSQG------ERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGA 1211 Query: 2169 ANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAA 2228 A +QG K+ G G+ E G D G E G Sbjct: 1212 AGPPGIQGSPGKEGPPGPQGPSGLPGIPGE---EGKEGRDGKPGPPGEPGKAGEPGLPGP 1268 Query: 2229 QGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHG 2266 +G G + A E A G+ ++ G Sbjct: 1269 EGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPG 1306 Score = 53.5 bits (127), Expect = 2e-06 Identities = 170/937 (18%), Positives = 262/937 (27%), Gaps = 75/937 (8%) Query: 274 GIANEDAAQGIANEDAA---QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIA 330 G D ++G+ E G+ E ++G + G V A G+ E Sbjct: 539 GPPGRDGSKGMRGEPGELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGE------- 591 Query: 331 KPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALH 390 E T+G E DG + G GVA +G V Sbjct: 592 --------RGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVAGPQGEKGDVGPAGPP 643 Query: 391 GVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANE 450 GV + + + A G A G A+G G ++G + Sbjct: 644 GVPGSVVQQEGLKGEQGAPGPRGHQGAPG---PPGARGPIGPEGRDGPPGLQGLRGKKGD 700 Query: 451 DAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGI 510 GI QG V G G+ E+ G D G Sbjct: 701 MGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGP 760 Query: 511 ANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVAT 570 +G E DG+ + + G E G E + G+ E Sbjct: 761 PGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGD 820 Query: 571 QGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAV----------QGVANEDAVHGVAN 620 QG E G+ + G A G+ ++ QG E G+ Sbjct: 821 QGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPG 880 Query: 621 EDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAH 680 E QG E+ G +G G N A + P + G V A Sbjct: 881 EPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPS-GPPGSVGAP 939 Query: 681 GIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANED 740 G+ G E A G G + G+ +D G+ Sbjct: 940 GLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKG----KDGEPGLRGSP 995 Query: 741 AVHGVAKEVAAHGVANEDPVQGVANEDVV-QGVANEVEVQGIAHEDAVQGIANEDAAHGI 799 + G AA G V+G N + Q V + GI +G D G+ Sbjct: 996 GLPGPLGTKAACG-----KVRGSENCALGGQCVKGDRGAPGIPGSPGSRG----DPGIGV 1046 Query: 800 ANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNEDAV 859 A G + + G ++G+ G A D A G E G ++ Sbjct: 1047 AGPPGPSGPPGDKGSPG------SRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSL 1100 Query: 860 QGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAH 919 + L V N+ P ++GV + +G TE K Sbjct: 1101 LSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREG--TE------GKKGEA 1152 Query: 920 GITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANED 979 G IA + D G + GV G A G+A Sbjct: 1153 GPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIA--- 1209 Query: 980 AVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIA 1039 G A +QG + G + GI E+ G + G + G+ Sbjct: 1210 ---GAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLP 1266 Query: 1040 NEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANE------DAAQGIAHEDAVQGIA 1093 + A+G G + + G E A G+ + D G QG Sbjct: 1267 GPEGARG---PPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPR 1323 Query: 1094 NEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAH 1153 +G G + +G E+ G+ + +G E +G+ ++ Sbjct: 1324 GPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVP 1383 Query: 1154 GIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQG 1190 G E G + +G +G + + G Sbjct: 1384 GKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPG 1420 >gi|5803080 macrophage receptor with collagenous structure [Homo sapiens] Length = 520 Score = 59.3 bits (142), Expect = 4e-08 Identities = 58/290 (20%), Positives = 84/290 (28%), Gaps = 6/290 (2%) Query: 1243 DGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKE 1302 D + E A G+ G+ G E +G D A G + Sbjct: 135 DNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGP 194 Query: 1303 DPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDI 1362 GV E +QG QG QG G+ G E + Sbjct: 195 QGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGL 254 Query: 1363 ANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAV 1422 +G+ + V G ++G G+A +G + +QGV Sbjct: 255 PGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGA 314 Query: 1423 QGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE 1482 G G A G+ + G ++G QG E V G A Sbjct: 315 VGHPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPA-- 372 Query: 1483 VAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHG 1532 GV E + +A P A G A + QG+ G+ E G Sbjct: 373 ----GVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERG 418 Score = 58.5 bits (140), Expect = 7e-08 Identities = 67/324 (20%), Positives = 100/324 (30%), Gaps = 30/324 (9%) Query: 1723 VAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVA 1782 V+HE +Q + N T I E A G+ G+ E Sbjct: 125 VSHEHLLQRVDN------FTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKG 178 Query: 1783 AHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISK 1842 A G D A + P G+ E QG G P + A G G Sbjct: 179 AKGAMGRDGATGPSGPQGPPGVKGEAGLQG------PQGAPGKQGATGTPGPQGEKGSKG 232 Query: 1843 EDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQG 1902 + + G E +G + + G + ++G A G+ A G ++G Sbjct: 233 DGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKGDA------GVMGPPGAQG------SKG 280 Query: 1903 IANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVA 1962 +A A+G + +QG+ A G G A G+ Sbjct: 281 DFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPG 340 Query: 1963 AHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIAN 2022 + G ++G QG E V G A GV E + +A P A G A Sbjct: 341 SPGATGLKGSKGDTGLQGQQGRKGESGVPGPA------GVKGEQGSPGLAGPKGAPGQAG 394 Query: 2023 EVAAQGIATEDVADGIANEDAAHG 2046 + QG+ G+ E G Sbjct: 395 QKGDQGVKGSSGEQGVKGEKGERG 418 Score = 58.2 bits (139), Expect = 1e-07 Identities = 54/273 (19%), Positives = 79/273 (28%), Gaps = 3/273 (1%) Query: 939 ITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVE 998 I E A G+ A G+ G E A+G D G + GV E Sbjct: 146 IKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAG 205 Query: 999 VQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISK 1058 +QG QG G G+ G E G+ G+ Sbjct: 206 LQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKG 265 Query: 1059 EDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV---AKEVAAHGVANEDP 1115 + V G ++G G+A +G + + GV V G E Sbjct: 266 DAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPG 325 Query: 1116 VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIAN 1175 G + G G+ G+ + G + G+ E + G+A Sbjct: 326 SAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPAGVKGEQGSPGLAG 385 Query: 1176 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHG 1208 A G A + QG+ GV E G Sbjct: 386 PKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERG 418 Score = 56.6 bits (135), Expect = 3e-07 Identities = 80/378 (21%), Positives = 120/378 (31%), Gaps = 26/378 (6%) Query: 1936 AQGIAKEDAVQG------IANEDAAQGIANEVAAHG---IANEDAAQGIANEDAAQGIAH 1986 AQG ++ +Q +++E Q + N G I E A G+ A G+ Sbjct: 107 AQGASRLQVLQAQLTWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPG 166 Query: 1987 EDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHG 2046 G E G D A + P G+ E QG G G Sbjct: 167 APGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQG 226 Query: 2047 VANEDAAQAIAKPDAAHGIANE----GIATEDVADGIAEDA-VQGITNEEAAQAIAKQDA 2101 + P G E G+ G+ DA V G + ++ + Sbjct: 227 EKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPG 286 Query: 2102 AHGITKEDAAQGVTNEVAAQGVANEDAA---HGVANEVAAHGVANEDAAQGVANEVAAQG 2158 G+ A+G + QGV A G E + G G A G Sbjct: 287 PPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPGATG 346 Query: 2159 VANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVA 2218 + G+ + +G + G+ E + G+A A G A + QGV Sbjct: 347 LKGSKGDTGLQGQQGRKGESGVPGPAGVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSG 406 Query: 2219 AQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHGIANEDAV----- 2273 QGV E +G N V+V V + + R G +D N DA+ Sbjct: 407 EQGVKGEKGERG-ENSVSVRIVGSSNRGRAEVYYSGTWGTICDDEWQ---NSDAIVFCRM 462 Query: 2274 HGIANEDAVYDIANDTVQ 2291 G + A+Y + T Q Sbjct: 463 LGYSKGRALYKVGAGTGQ 480 Score = 56.2 bits (134), Expect = 4e-07 Identities = 68/321 (21%), Positives = 97/321 (30%), Gaps = 15/321 (4%) Query: 1167 EDAAQGIANEDAAQG------IAHEDAVQGIANEDAVHGVAK---EVAAHGVANEDAAHA 1217 E AQG + Q ++HE +Q + N G+ + E A G+ A Sbjct: 104 EHLAQGASRLQVLQAQLTWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMG 163 Query: 1218 IAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDA 1277 + G E A+G D A G + GV E G QG Sbjct: 164 MPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPG 223 Query: 1278 AQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIAN 1337 QG G+ G E G+ +G+ + V G +G Sbjct: 224 PQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFG 283 Query: 1338 EDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQG 1397 G+A A+G + Q + A G G A G+ G Sbjct: 284 RPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPG 343 Query: 1398 VANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDA 1457 +G QG E V G A G+ E + G+A A G A + Sbjct: 344 ATGLKGSKGDTGLQGQQGRKGESGVPGPA------GVKGEQGSPGLAGPKGAPGQAGQKG 397 Query: 1458 AQGIAHEDAVQGIANEDAVHG 1478 QG+ QG+ E G Sbjct: 398 DQGVKGSSGEQGVKGEKGERG 418 Score = 54.3 bits (129), Expect = 1e-06 Identities = 67/324 (20%), Positives = 93/324 (28%), Gaps = 12/324 (3%) Query: 1032 EDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQG---IANEDAAQGIAHEDA 1088 E AQG + Q V +S E +Q + N G I E A G+ Sbjct: 104 EHLAQGASRLQVLQAQLTWVR---VSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKG 160 Query: 1089 VQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIAN 1148 G+ G E A G D G + GV E +QG QG Sbjct: 161 AMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATG 220 Query: 1149 EDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHG 1208 G G+ G E G+ +G+ + V G + G Sbjct: 221 TPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKG 280 Query: 1209 VANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDA 1268 +A A+G + QG+ A G G A G+ Sbjct: 281 DFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPG 340 Query: 1269 VQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAH 1328 G ++G QG E G A GV E G+A G A Sbjct: 341 SPGATGLKGSKGDTGLQGQQGRKGESGVPGPA------GVKGEQGSPGLAGPKGAPGQAG 394 Query: 1329 EDAVQGIANEDAAHGIANEDAAQG 1352 + QG+ G+ E +G Sbjct: 395 QKGDQGVKGSSGEQGVKGEKGERG 418 Score = 54.3 bits (129), Expect = 1e-06 Identities = 57/279 (20%), Positives = 80/279 (28%), Gaps = 6/279 (2%) Query: 921 ITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDA 980 I E+ A + A + G E A G D A G + GV E Sbjct: 146 IKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAG 205 Query: 981 VHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIAN 1040 + G QG QG G+ G E G+ +G+ Sbjct: 206 LQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKG 265 Query: 1041 EDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHG 1100 + G + G G+A A+G + QG+ G G Sbjct: 266 DAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPG 325 Query: 1101 VAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVA 1160 A G+ G +G QG E V G A G+ E Sbjct: 326 SAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPA------GVKGEQG 379 Query: 1161 AHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHG 1199 + G+A A G A + QG+ QG+ E G Sbjct: 380 SPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERG 418 Score = 53.9 bits (128), Expect = 2e-06 Identities = 61/297 (20%), Positives = 86/297 (28%), Gaps = 24/297 (8%) Query: 68 ITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDA 127 I E G+ A G+ G E A G D A G + GV E Sbjct: 146 IKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAG 205 Query: 128 VQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIAN 187 +QG QG QG G+ G E D+ + D Sbjct: 206 LQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKG--DLGLPGSKGD--- 260 Query: 188 EDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQG 247 +G+ + V G ++G G+A +G + +QGV G Sbjct: 261 ----RGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVG 316 Query: 248 VAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDA 307 G A G+ + G ++G QG E V G A Sbjct: 317 HPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPA---- 372 Query: 308 VHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHG 364 GV E + +A P A G A + QG+ G+ E G Sbjct: 373 -----------GVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERG 418 Score = 53.1 bits (126), Expect = 3e-06 Identities = 58/279 (20%), Positives = 82/279 (29%), Gaps = 6/279 (2%) Query: 1651 IANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDA 1710 I E A G+ A G+ G E G A G + GV E Sbjct: 146 IKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAG 205 Query: 1711 VQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIAN 1770 +QG QG QG G+ G E G+ +G+ Sbjct: 206 LQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKG 265 Query: 1771 EDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHG 1830 + V + G +A A+G + QG+ A G P G Sbjct: 266 DAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPG 325 Query: 1831 VANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDA 1890 A G+ G ++G QG E V G A G+ E Sbjct: 326 SAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPA------GVKGEQG 379 Query: 1891 AHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQG 1929 + G+A A G A + Q + QG+ E +G Sbjct: 380 SPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERG 418 Score = 52.8 bits (125), Expect = 4e-06 Identities = 57/300 (19%), Positives = 89/300 (29%), Gaps = 9/300 (3%) Query: 1002 IAHKDAIQGIANEDAAHG---IANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISK 1058 ++H+ +Q + N G I E A G+ A G+ G E A G Sbjct: 125 VSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMG 184 Query: 1059 EDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQG 1118 D G + G+ E QG QG G G+ G Sbjct: 185 RDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETG 244 Query: 1119 VANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDA 1178 E G+ +G+ + V G + G G+A A+G + Sbjct: 245 TKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPG 304 Query: 1179 AQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIAT 1238 QG+ G G A G+ + A G+ G+ Sbjct: 305 LQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGS------PGATGLKGSKGDTGLQG 358 Query: 1239 EDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQG 1298 + G + GV E + G++ G A + QG+ QG+ E +G Sbjct: 359 QQGRKGESGVPGPAGVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERG 418 Score = 52.4 bits (124), Expect = 5e-06 Identities = 68/343 (19%), Positives = 101/343 (29%), Gaps = 13/343 (3%) Query: 1137 VAHEDAVQGIANEDAAHG---IANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIAN 1193 V+HE +Q + N G I E A G+ A G+ G E +G Sbjct: 125 VSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMG 184 Query: 1194 EDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHG 1253 D G + GV E +G QG G+ G Sbjct: 185 RDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETG 244 Query: 1254 VANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDP 1313 E G+ +G+ + G +G G+A +G + Sbjct: 245 TKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPG 304 Query: 1314 IQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISK 1373 +QGV G G A G+ + G ++ QG Sbjct: 305 LQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKG 364 Query: 1374 EDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHG 1433 E V G A G+ E G+A G A + QGV QG+ E G Sbjct: 365 ESGVPGPA------GVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERG 418 Query: 1434 IANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAV 1476 N V+ + + + + G +D Q N DA+ Sbjct: 419 -ENSVSVRIVGSSNRGRAEVYYSGTWGTICDDEWQ---NSDAI 457 Score = 51.6 bits (122), Expect = 9e-06 Identities = 89/411 (21%), Positives = 136/411 (33%), Gaps = 34/411 (8%) Query: 528 IANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADG------ 581 I ED + + A H +A E + KP +G+ +A I + G Sbjct: 6 ILKEDELLSETQQAAFHQIAMEPFEINVPKPKRRNGVNFSLAVVVIYLILLTAGAGLLVV 65 Query: 582 -IANEDAAHGVANEVAVHG-VAIEDAVQGVANEDAVHGVANEDAAQGIAK------EVTA 633 + N A V ++ +A ED+ + A G E AQG ++ ++T Sbjct: 66 QVLNLQARLRVLEMYFLNDTLAAEDSPSFSLLQSAHPG---EHLAQGASRLQVLQAQLTW 122 Query: 634 HGVANEDAVQGVVNEDALHGV--VANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGI 691 V++E +Q V N G+ + E A + A G+ G E A+G Sbjct: 123 VRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGA 182 Query: 692 ANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAA 751 D A G + G+ E +QG QG QG G+ Sbjct: 183 MGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGE 242 Query: 752 HGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANE 811 G E G+ +G+ + V G +G G+A A G + Sbjct: 243 TGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQ 302 Query: 812 DAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVT------NEDAVQGVVNE 865 QGV A G G A G+ + G T + +QG Sbjct: 303 PGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGR 362 Query: 866 EALHGV-----VANEDAAQAIAKPDAAHGIA----NEGVANEVAAQGIATE 907 + GV V E + +A P A G A ++GV QG+ E Sbjct: 363 KGESGVPGPAGVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGE 413 Score = 51.2 bits (121), Expect = 1e-05 Identities = 50/268 (18%), Positives = 78/268 (29%), Gaps = 3/268 (1%) Query: 1804 IANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDP 1863 I E A G+ A G+P G E A G D G + G+ E Sbjct: 146 IKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAG 205 Query: 1864 IQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISK 1923 +QG QG QG G+ G E + +G+ Sbjct: 206 LQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKG 265 Query: 1924 EDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAA---QGIANEDA 1980 + V G ++G G+A A+G + G+ A G E Sbjct: 266 DAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPG 325 Query: 1981 AQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIAN 2040 + G + G G+ + +G + G+ E + G+A Sbjct: 326 SAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPAGVKGEQGSPGLAG 385 Query: 2041 EDAAHGVANEDAAQAIAKPDAAHGIANE 2068 A G A + Q + G+ E Sbjct: 386 PKGAPGQAGQKGDQGVKGSSGEQGVKGE 413 Score = 50.8 bits (120), Expect = 2e-05 Identities = 58/300 (19%), Positives = 89/300 (29%), Gaps = 9/300 (3%) Query: 1705 VANEDAVQGVANEVEVQG---VAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAH 1761 V++E +Q V N + G + E G+ A G+ G E A+G Sbjct: 125 VSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMG 184 Query: 1762 EDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADG 1821 D G + V E G +G G+ G Sbjct: 185 RDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETG 244 Query: 1822 IPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDA 1881 E G+ G+ + V G ++G G+A +G + Sbjct: 245 TKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPG 304 Query: 1882 VQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAK 1941 +QG+ A G G A + + G + +G QG Sbjct: 305 LQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKG 364 Query: 1942 EDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHG 2001 E V G A G+ E + G+A A G A + QG+ QG+ E G Sbjct: 365 ESGVPGPA------GVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERG 418 Score = 50.1 bits (118), Expect = 3e-05 Identities = 61/316 (19%), Positives = 93/316 (29%), Gaps = 6/316 (1%) Query: 167 IANEDAAQDIAKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDP 226 I E A + A + G E +G D A G + GV E Sbjct: 146 IKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAG 205 Query: 227 VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAN 286 +QG QG QG G+ G E G+ +G+ Sbjct: 206 LQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKG 265 Query: 287 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQG 346 + G +G G+A A G + + P A G G Sbjct: 266 DAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPG 325 Query: 347 IATEDVADGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGV--VANEDAAQAIAK 404 A G+ + G + G QG E + G V E + +A Sbjct: 326 SAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPAGVKGEQGSPGLAG 385 Query: 405 PDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQG 464 P A G A + G+ QG+ E G +V+ + + + + + G Sbjct: 386 PKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERG-ENSVSVRIVGSSNRGRAEVYYSGTWG 444 Query: 465 IAHEDAVQGIANEDAV 480 +D Q N DA+ Sbjct: 445 TICDDEWQ---NSDAI 457 Score = 49.7 bits (117), Expect = 3e-05 Identities = 55/280 (19%), Positives = 80/280 (28%), Gaps = 7/280 (2%) Query: 573 IATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVT 632 I E A G+ A G+ G E +G D G + G+ E Sbjct: 146 IKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAG 205 Query: 633 AHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIA 692 G QG G ++ I P G E G+ +G+ Sbjct: 206 LQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIG-PKGETGTKGEKGDLGLPGSKGDRGMK 264 Query: 693 NEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAH 752 + G + G G+A A+G + +QG+ G V Sbjct: 265 GDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVP------GPPGAVGHP 318 Query: 753 GVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANED 812 G E G + G G+ G+ + G + GV E Sbjct: 319 GAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPAGVKGEQ 378 Query: 813 AAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHG 852 + G+A A G A + GV QGV E G Sbjct: 379 GSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERG 418 Score = 48.9 bits (115), Expect = 6e-05 Identities = 61/289 (21%), Positives = 84/289 (29%), Gaps = 16/289 (5%) Query: 546 VANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDA 605 + E A + A G+ G E A G D A G + GV E Sbjct: 146 IKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAG 205 Query: 606 VQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIA 665 +QG G QG G + + G E G E + Sbjct: 206 LQGPQGAPGKQGATGTPGPQG------EKGSKGDGGLIGPKGETGTKG----EKGDLGLP 255 Query: 666 KPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQ 725 G+ + G ++G G+A A G + +QG+ A Sbjct: 256 GSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAV 315 Query: 726 GIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHED 785 G G A G+ + G +G QG E V G A Sbjct: 316 GHPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPA--- 372 Query: 786 AVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHG 834 G+ E + G+A A G A + QGV QGV E G Sbjct: 373 ---GVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERG 418 Score = 48.5 bits (114), Expect = 8e-05 Identities = 59/306 (19%), Positives = 85/306 (27%), Gaps = 16/306 (5%) Query: 1633 IANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVA 1692 I E A G+ G+ G E A+G D G + GV E Sbjct: 146 IKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAG 205 Query: 1693 AHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIAN 1752 G QG QG G+ G E G+ G+ Sbjct: 206 LQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKG 265 Query: 1753 EDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQG 1812 + G +G +A A G + + P A G G Sbjct: 266 DAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPG 325 Query: 1813 IATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVE 1872 A G+P + G + G + QG E G A Sbjct: 326 SAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPA------------- 372 Query: 1873 VQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDA-VQGIA 1931 GV E G+A A G A + QG+ Q + E +G + + G + Sbjct: 373 --GVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERGENSVSVRIVGSS 430 Query: 1932 NQDAAQ 1937 N+ A+ Sbjct: 431 NRGRAE 436 Score = 47.8 bits (112), Expect = 1e-04 Identities = 53/262 (20%), Positives = 77/262 (29%), Gaps = 15/262 (5%) Query: 920 GITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANED 979 G E+ A+ +D A + GV E G QG QG Sbjct: 172 GPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQG----- 226 Query: 980 AVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIA 1039 G + + G E +G + G+ G+ + G ++G Sbjct: 227 -EKGSKGDGGLIGPKGETGTKG---EKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDF 282 Query: 1040 NEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVH 1099 G+A A G + +QG+ A G G A G+ Sbjct: 283 GRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSP 342 Query: 1100 GVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEV 1159 G + G QG E V G A GV E G+A A G A + Sbjct: 343 GATGLKGSKGDTGLQGQQGRKGESGVPGPA------GVKGEQGSPGLAGPKGAPGQAGQK 396 Query: 1160 AAHGIANEDAAQGIANEDAAQG 1181 G+ QG+ E +G Sbjct: 397 GDQGVKGSSGEQGVKGEKGERG 418 Score = 47.4 bits (111), Expect = 2e-04 Identities = 61/315 (19%), Positives = 91/315 (28%), Gaps = 11/315 (3%) Query: 188 EDAAQGISKEDAVQG------IANEDAAQGIAKEDPVQG---VANEDPVQGVANEDAVQG 238 E AQG S+ +Q +++E Q + G + E G+ G Sbjct: 104 EHLAQGASRLQVLQAQLTWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMG 163 Query: 239 VANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDA 298 + G E +G D A G + G+ E QG QG Sbjct: 164 MPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPG 223 Query: 299 VQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIAN 358 QG G+ G E + G+ + G + G Sbjct: 224 PQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFG 283 Query: 359 EDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAH--GIANEVA 416 G+A A G + +QGV G + + P A G Sbjct: 284 RPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPG 343 Query: 417 AHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIAN 476 A G+ G+ + G S G+ E + G+A A G A + QG+ Sbjct: 344 ATGLKGSKGDTGLQGQQGRKGESGVPGPAGVKGEQGSPGLAGPKGAPGQAGQKGDQGVKG 403 Query: 477 EDAVHGVAKEVAAHG 491 GV E G Sbjct: 404 SSGEQGVKGEKGERG 418 Score = 47.4 bits (111), Expect = 2e-04 Identities = 55/279 (19%), Positives = 79/279 (28%), Gaps = 6/279 (2%) Query: 1606 IANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDA 1665 I E A + A G+ G E A G D G + G+ E Sbjct: 146 IKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAG 205 Query: 1666 AQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAH 1725 QG QG G G+ G E G+ +G+ Sbjct: 206 LQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKG 265 Query: 1726 EDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHG 1785 + V G + G G+A A+G + +QG+ V G Sbjct: 266 DAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGA------VGHPG 319 Query: 1786 VANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDA 1845 E + G A G+ G+ + G + G+ E Sbjct: 320 AKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPAGVKGEQG 379 Query: 1846 VQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQG 1884 G+A A G A + QGV QGV E +G Sbjct: 380 SPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERG 418 Score = 47.4 bits (111), Expect = 2e-04 Identities = 48/262 (18%), Positives = 71/262 (27%), Gaps = 3/262 (1%) Query: 65 AHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVAN 124 A G+ G+ G E A G A G + GV E QG Sbjct: 152 APGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAGLQGPQG 211 Query: 125 EDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQD 184 QG QG G+ G E G+ + + + Sbjct: 212 APGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKGDAGVMG 271 Query: 185 IANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPV---QGVANEDAVQGVAN 241 ++G G+A A+G + +QGV G E G Sbjct: 272 PPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPG 331 Query: 242 EVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQG 301 + G G+ G+ + G + G+ E + G+A G Sbjct: 332 RAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPAGVKGEQGSPGLAGPKGAPG 391 Query: 302 IANEDAVHGVAKEVAAHGVANE 323 A + GV GV E Sbjct: 392 QAGQKGDQGVKGSSGEQGVKGE 413 Score = 47.0 bits (110), Expect = 2e-04 Identities = 73/372 (19%), Positives = 115/372 (30%), Gaps = 30/372 (8%) Query: 838 EDAAQGVAK------EVTAHGVTNEDAVQGVVNEEALHGV--VANEDAAQAIAKPDAAHG 889 E AQG ++ ++T V++E +Q V N G+ + E A + A G Sbjct: 104 EHLAQGASRLQVLQAQLTWVRVSHEHLLQRVDNFTQNPGMFRIKGEQGAPGLQGHKGAMG 163 Query: 890 IANE----GVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAA 945 + G E A+G + +D A G + + + + Sbjct: 164 MPGAPGPPGPPAEKGAKG--------AMGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGK 215 Query: 946 QGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHK 1005 QG G G+ G E G+ +G+ + V G Sbjct: 216 QGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGA 275 Query: 1006 DAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGI 1065 +G G+A A G + QG+ A G G + G+ Sbjct: 276 QGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGL 335 Query: 1066 ANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAV 1125 + G ++G QG E V G A GV E G+A Sbjct: 336 PGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPA------GVKGEQGSPGLAGPKGA 389 Query: 1126 QGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHE 1185 G A + QGV QG+ E G N V+ + + + + G + Sbjct: 390 PGQAGQKGDQGVKGSSGEQGVKGEKGERG-ENSVSVRIVGSSNRGRAEVYYSGTWGTICD 448 Query: 1186 DAVQGIANEDAV 1197 D Q N DA+ Sbjct: 449 DEWQ---NSDAI 457 Score = 45.1 bits (105), Expect = 8e-04 Identities = 70/367 (19%), Positives = 109/367 (29%), Gaps = 40/367 (10%) Query: 1272 IANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQG------VANEDPIQGVANEVEVQG 1325 +A ED+ + A G E AQG ++ +Q V++E +Q V N + G Sbjct: 86 LAAEDSPSFSLLQSAHPG---EHLAQGASRLQVLQAQLTWVRVSHEHLLQRVDNFTQNPG 142 Query: 1326 VAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDA 1385 + I E A G+ A G+ E A+G D G + Sbjct: 143 MFR------IKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQG 196 Query: 1386 AQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIAN 1445 G+ E +QG QG QG G+ G E G+ Sbjct: 197 PPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPG 256 Query: 1446 EDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARG 1505 +G+ + G +G G+A A G + + P A G Sbjct: 257 SKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVG 316 Query: 1506 IANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVT 1565 G A G+ + G ++G + +QG Sbjct: 317 HPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKG------------DTGLQG------ 358 Query: 1566 AHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIA 1625 G E V G V E + +A P A G A + + QG+ Sbjct: 359 QQGRKGESGVPGPAG-------VKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVK 411 Query: 1626 NQDAAQG 1632 + +G Sbjct: 412 GEKGERG 418 Score = 44.7 bits (104), Expect = 0.001 Identities = 65/342 (19%), Positives = 102/342 (29%), Gaps = 25/342 (7%) Query: 1446 EDAAQGIANEDAAQG------IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAK 1499 E AQG + Q ++HE +Q + N G+ + + E A + Sbjct: 104 EHLAQGASRLQVLQAQLTWVRVSHEHLLQRVDNFTQNPGMFR------IKGEQGAPGLQG 157 Query: 1500 PDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQG 1559 A G+ G E A G D A G + G+ E + G QG Sbjct: 158 HKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQG 217 Query: 1560 VVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKD 1619 G G++ + E + G+ + Sbjct: 218 ATGTPGPQGEKGSKGDGGLIGPKG-ETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQ 276 Query: 1620 AAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIA 1679 ++G + G+A A G + +QG+ A G G A G+ Sbjct: 277 GSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLP 336 Query: 1680 NEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAH 1739 G + G QG E V G A GV E G+A A Sbjct: 337 GSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPA------GVKGEQGSPGLAGPKGAP 390 Query: 1740 GITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEV 1781 G + G+ +G + E V+G E +SV+ + Sbjct: 391 GQAGQKGDQGV------KGSSGEQGVKGEKGERGENSVSVRI 426 Score = 43.9 bits (102), Expect = 0.002 Identities = 48/245 (19%), Positives = 72/245 (29%), Gaps = 9/245 (3%) Query: 57 IANEDADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANE 116 + + A G V+G A QG + A G G + G E Sbjct: 183 MGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGE 242 Query: 117 VAAQGVANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDI 176 +G E G+ +G+ + V G + G G+A A+ Sbjct: 243 TGTKG---EKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGD 299 Query: 177 AKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAV 236 + Q + A G G A G+ G +G Sbjct: 300 QGQPGLQGVPGPPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQ 359 Query: 237 QGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHE 296 QG E V G A G+ E + G+ A G A + QG+ QG+ E Sbjct: 360 QGRKGESGVPGPA------GVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGE 413 Query: 297 DAVQG 301 +G Sbjct: 414 KGERG 418 Score = 42.4 bits (98), Expect = 0.006 Identities = 53/287 (18%), Positives = 85/287 (29%), Gaps = 7/287 (2%) Query: 1588 VANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDA 1647 + E A + A G+ + A+G +D A G + G+ E Sbjct: 146 IKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAG 205 Query: 1648 VQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVAN 1707 +QG QG QG G+ G E G+ +G+ Sbjct: 206 LQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKG 265 Query: 1708 EDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQG 1767 + V G +G G+A A G + G+ A G G Sbjct: 266 DAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEPG 325 Query: 1768 IANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDA 1827 A G A + G+ + +G + G+ E Sbjct: 326 SAGSPG------RAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPAGVKGEQG 379 Query: 1828 AHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQ 1874 + G+A A G + + QG+ QG+ E +G N V V+ Sbjct: 380 SPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERG-ENSVSVR 425 Score = 41.6 bits (96), Expect = 0.009 Identities = 52/274 (18%), Positives = 78/274 (28%), Gaps = 4/274 (1%) Query: 356 IANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEV 415 I E A G+ A G+ G E G + D A + P G+ E Sbjct: 146 IKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGR-DGATGPSGPQGPPGVKGEA 204 Query: 416 AAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIA 475 G QG G G+ G E G+ +G+ Sbjct: 205 GLQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMK 264 Query: 476 NEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVA---DGIANED 532 + V G + G + +A A+G + QG+ A G E Sbjct: 265 GDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPGPPGAVGHPGAKGEP 324 Query: 533 AVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVA 592 G G A + G+ + +G + G+ E + G+A Sbjct: 325 GSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPAGVKGEQGSPGLA 384 Query: 593 NEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQG 626 G A + QGV GV E +G Sbjct: 385 GPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERG 418 Score = 39.7 bits (91), Expect = 0.036 Identities = 61/306 (19%), Positives = 90/306 (29%), Gaps = 15/306 (4%) Query: 510 IANEVAAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVA 569 I E A G+ A G+ G E A G D A + P G+ E Sbjct: 146 IKGEQGAPGLQGHKGAMGMPGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAG 205 Query: 570 TQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAK 629 QG G G G+ G E G+ +G+ Sbjct: 206 LQGPQGAPGKQGATGTPGPQGEKGSKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKG 265 Query: 630 EVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQ 689 + G +G G+ A +P G+ A G Sbjct: 266 DAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQP-GLQGVPGPPGAVGHPGAKGEP 324 Query: 690 GIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEV 749 G A G+ + G + +G QG E V G A GV E Sbjct: 325 GSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPGPA------GVKGEQ 378 Query: 750 AAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVA 809 + G+A G A + QGV +G + E V+G E + ++ + G + Sbjct: 379 GSPGLAGPKGAPGQAGQKGDQGV------KGSSGEQGVKGEKGERGENSVSVRIV--GSS 430 Query: 810 NEDAAQ 815 N A+ Sbjct: 431 NRGRAE 436 Score = 35.0 bits (79), Expect = 0.88 Identities = 30/168 (17%), Positives = 52/168 (30%), Gaps = 3/168 (1%) Query: 56 DIANEDADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVAN 115 D+ + G+ + V G ++G G+A A G + QGV Sbjct: 251 DLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGRPGPPGLAGFPGAKGDQGQPGLQGVPG 310 Query: 116 E---VAAQGVANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDA 172 V G E G + G G+ G+ + +G + Sbjct: 311 PPGAVGHPGAKGEPGSAGSPGRAGLPGSPGSPGATGLKGSKGDTGLQGQQGRKGESGVPG 370 Query: 173 AQDIAKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQG 220 + E + +A A G + + QG+ QG+ E +G Sbjct: 371 PAGVKGEQGSPGLAGPKGAPGQAGQKGDQGVKGSSGEQGVKGEKGERG 418 >gi|11386161 alpha 2 type IX collagen [Homo sapiens] Length = 689 Score = 57.4 bits (137), Expect = 2e-07 Identities = 110/566 (19%), Positives = 161/566 (28%), Gaps = 31/566 (5%) Query: 1001 GIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKED 1060 G+ D I G G G A D G D G E GI Sbjct: 42 GVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVK 101 Query: 1061 AVQGIANEDAAQGIA-----NEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANED- 1114 G+ G G+ E ++G + G + G Sbjct: 102 GQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPG 161 Query: 1115 PVQGVANE-------DAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANE 1167 +QG+ + G+ +QGV +GI + G G + E Sbjct: 162 TIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGE 221 Query: 1168 DAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGI 1227 QGI QGI + G E HG V A G P G Sbjct: 222 ---QGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGE 278 Query: 1228 ANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAV 1287 + + GI GI A G G ++G A + G + Sbjct: 279 KGDEGSPGIRG---PQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGL 335 Query: 1288 QGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANE 1347 G+ + +G + G G + G E QGI + G E Sbjct: 336 AGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQG---E 392 Query: 1348 DAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGV 1407 G Q E GI + G+ + + G K P +G + V G+ Sbjct: 393 RGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPG--KTGP-RGKVGDPGVAGL 449 Query: 1408 ANEVEVQGVAHE---DAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHE 1464 E +G + E QG+ E G + + A G+ G +G+ + Sbjct: 450 PGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQ 509 Query: 1465 DAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGI 1524 QG+ DA +VA + + A A++ A R V G G Sbjct: 510 PGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVS---AKREALGAVGMMGPPGPPGPPGY 566 Query: 1525 ANEDAAHGVANEVAAQGIANEVAVHG 1550 + HG GI V G Sbjct: 567 PGKQGPHGHPGPRGVPGIVGAVGQIG 592 Score = 55.1 bits (131), Expect = 8e-07 Identities = 98/499 (19%), Positives = 144/499 (28%), Gaps = 40/499 (8%) Query: 1785 GVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKED 1844 GV D P G G A D DG P D G E GI Sbjct: 42 GVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVK 101 Query: 1845 AVQGIANEDAAQGIAKEDPIQ-----GVANEVEVQGVAHEDAVQGIANEDAAHGIANEDA 1899 G+ G P G+ E+ ++G + G + G Sbjct: 102 GQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPG 161 Query: 1900 A-QGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIA 1958 QG+ E +A + + G+ +QG+ +GI + QG G Sbjct: 162 TIQGL--EGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQG------KPGPK 213 Query: 1959 NEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAAR 2018 +V A G QGI QGI + G E HG A P Sbjct: 214 GDVGASG------EQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEE 267 Query: 2019 GIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGI----ANEGIATED 2074 G G ++ + GI G I D G + G A + Sbjct: 268 GPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQP 327 Query: 2075 VADGI-------AEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANED 2127 + G + +G ++ G ++ G E+ QG+ + Sbjct: 328 GSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQK 387 Query: 2128 AAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIA 2187 G V G QG E G+ + GV + +G K +G Sbjct: 388 GDQGERGPV---GQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGD---KGSPGKTGPRGKV 441 Query: 2188 NEDAAQGVANEVAAHGVANE---DAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANED 2244 + G+ E G + E QGV E G + + A GV G Sbjct: 442 GDPGVAGLPGEKGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLA 501 Query: 2245 AARHMAKEDAAQGIANEDA 2263 R + + QG+ DA Sbjct: 502 GNRGVPGQPGRQGVEGRDA 520 Score = 53.1 bits (126), Expect = 3e-06 Identities = 95/513 (18%), Positives = 144/513 (28%), Gaps = 22/513 (4%) Query: 1713 GVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANED 1772 G+ +QGV +GI + G G + E QGI QGI Sbjct: 181 GMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGE---QGIPGPPGPQGIRGYP 237 Query: 1773 AVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVA 1832 + E HG A P G G ++ + GI G Sbjct: 238 GMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPK 297 Query: 1833 NEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAH 1892 GI+ +D G + G A + G QG+A V G Sbjct: 298 GATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPG------HQGLA---GVPGQPGTKGGP 348 Query: 1893 GIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANED 1952 G E QG+ E +G + G +G + QG Sbjct: 349 GDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPK 408 Query: 1953 AAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIA 2012 QG G+ +G + +G + V G+ E G + E Sbjct: 409 GEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPG----- 463 Query: 2013 KPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIAT 2072 P +G+ E G + + A G+ G + + G+ Sbjct: 464 -PKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATD 522 Query: 2073 EDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGV 2132 + + D +A +Q E A A + A G+ G QG GV Sbjct: 523 QHIVD-VALKMLQEQLAEVAVSAKREALGAVGMMGPPGPPGPPGYPGKQGPHGHPGPRGV 581 Query: 2133 ANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHK--DAIQGIANED 2190 V A G +G E G G+ + G+ + AI G + Sbjct: 582 PGIVGAVGQIGNTGPKGKRGEKGDPGEVGR-GHPGMPGPPGIPGLPGRPGQAINGKDGDR 640 Query: 2191 AAQGVANEVAAHGVANEDAAQGVANEVAAQGVA 2223 + G E G+ G A G + Sbjct: 641 GSPGAPGEAGRPGLPGPVGLPGFCEPAACLGAS 673 Score = 51.6 bits (122), Expect = 9e-06 Identities = 117/671 (17%), Positives = 191/671 (28%), Gaps = 59/671 (8%) Query: 579 ADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVAN 638 +DGI ++ G A G G A D G D G E G+ Sbjct: 46 SDGIDGDNGPPGKAGPPGPKGEP------GKAGPDGPDGKPGIDGLTGAKGEPGPMGIPG 99 Query: 639 EDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQ 698 G+ L G P G+ E+ G + G + Sbjct: 100 VKGQPGLPGPPGLPG-----PGFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPP 154 Query: 699 GIANEVAA-HGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANE 757 G G+ E + + + G+ +QG+ G+ + G Sbjct: 155 GKPGRPGTIQGL--EGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGP 212 Query: 758 DPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGV 817 G + E QG+ QGI + G E HG V A G +G Sbjct: 213 KGDVGASGE---QGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGP 269 Query: 818 ANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGVTNED------AVQGVVNEEALHGV 871 G ++ G+ G G+ +D ++G + G Sbjct: 270 RGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGS 329 Query: 872 VANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIA 931 ++ A +P G ++G E QG+ G K+ G E Q I Sbjct: 330 PGHQGLAGVPGQPGTKGGPGDQG---EPGPQGLPGFSGPPG--KEGEPGPRGEIGPQGIM 384 Query: 932 KQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQ 991 Q +G E G QG E G+ + GV + + Sbjct: 385 GQ------------KGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGD---K 429 Query: 992 GVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEV 1051 G + +G + G+ E G + E G QG+ E G + + Sbjct: 430 GSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKG------QQGVRGEPGYPGPSGDA 483 Query: 1052 AAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVA 1111 A G+ G +G+ + QG+ DA + A+ + +++A V+ Sbjct: 484 GAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVS 543 Query: 1112 NEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQ 1171 + G + G G + G GI V G + Sbjct: 544 AKREALGAV---GMMGPPGPPGPPGYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKR 600 Query: 1172 GIANEDAAQGIAH-----EDAVQGIANE--DAVHGVAKEVAAHGVANEDAAHAIAKPDAA 1224 G + G H + G+ A++G + + G E + P Sbjct: 601 GEKGDPGEVGRGHPGMPGPPGIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGL 660 Query: 1225 RGIANEVAAQG 1235 G A G Sbjct: 661 PGFCEPAACLG 671 Score = 50.4 bits (119), Expect = 2e-05 Identities = 80/423 (18%), Positives = 122/423 (28%), Gaps = 17/423 (4%) Query: 1821 GIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGI-AKEDPIQGVANEVEVQGVAHE 1879 G P G+ E+ G + G + G + IQG+ + + Sbjct: 119 GPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPGTIQGLEGSADF--LCPT 176 Query: 1880 DAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGI 1939 + G+ G+ +GI + Q G S E QGI QGI Sbjct: 177 NCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGE---QGIPGPPGPQGI 233 Query: 1940 AKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAV 1999 + G E G V A G +G G ++ GI + Sbjct: 234 RGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGI 293 Query: 2000 HGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVA---DGIANEDAAHGVANEDAAQAI 2056 G I D G + G A + + G+A G Q Sbjct: 294 TGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGE 353 Query: 2057 AKPDAAHGIANE-GIATEDVADG-IAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGV 2114 P G + G E G I + G ++ + Q G QG Sbjct: 354 PGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGP 413 Query: 2115 TNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEV 2174 QG+ G + G + G+ E +G + E +G Sbjct: 414 PGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKGQ------ 467 Query: 2175 QGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANE 2234 QG+ + G + + A GV G +GV + QGV DA + Sbjct: 468 QGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDATDQHIVD 527 Query: 2235 VAV 2237 VA+ Sbjct: 528 VAL 530 Score = 49.3 bits (116), Expect = 5e-05 Identities = 84/445 (18%), Positives = 128/445 (28%), Gaps = 40/445 (8%) Query: 419 GIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANED 478 G+ QG+ GI + QG G + E QGI QGI Sbjct: 181 GMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASGE---QGIPGPPGPQGIRGYP 237 Query: 479 AVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAVHGVA 538 + G E HG A P G G ++ + GI + G Sbjct: 238 GMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPK 297 Query: 539 NEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVH 598 G+ +D G +G A + G GV + Sbjct: 298 GATGPPGINGKD------------GTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTK 345 Query: 599 GVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANE 658 G + G G ++ G E+ G+ + QG E Sbjct: 346 GGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQG-------------E 392 Query: 659 DAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGI 718 P G E GI G+ + + G + G + V G+ Sbjct: 393 RGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPG---KTGPRGKVGDPGVAGL 449 Query: 719 ANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEV 778 E +G + E +G + V G G A VQG +G+A Sbjct: 450 PGEKGEKGESGEPGPKG---QQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGN--- 503 Query: 779 QGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANE 838 +G+ + QG+ DA +VA + + A V+ + A G + G Sbjct: 504 RGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALGAV---GMMGPPGP 560 Query: 839 DAAQGVAKEVTAHGVTNEDAVQGVV 863 G + HG V G+V Sbjct: 561 PGPPGYPGKQGPHGHPGPRGVPGIV 585 Score = 49.3 bits (116), Expect = 5e-05 Identities = 81/471 (17%), Positives = 130/471 (27%), Gaps = 31/471 (6%) Query: 62 ADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQG 121 A GI QG+ G E HG V A G +G G Sbjct: 218 ASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAG 277 Query: 122 VANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAA---QDIA- 177 ++ G+ + G GI +D G + G A + + Q +A Sbjct: 278 EKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAG 337 Query: 178 -----KEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVAN 232 E QG+ G E +G + G + +G Sbjct: 338 VPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVG 397 Query: 233 EDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQG 292 + QG QG QG+ G + G + G+ E +G Sbjct: 398 QPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKG 457 Query: 293 IAHE---DAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIAT 349 + E QG+ E G + + A GV G+ + QG+ Sbjct: 458 ESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQGVEG 517 Query: 350 EDVADGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAH 409 D D + A + +++ V+ + G V G P Sbjct: 518 RDATDQHIVDVALKMLQEQLAEVAVSAKREALGAVGMMGPPG-------------PPGPP 564 Query: 410 GIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHED 469 G + HG GI V G + +G + G H G+ Sbjct: 565 GYPGKQGPHGHPGPRGVPGIVGAVGQIGNTGPKGKRGEKGDPGEVGRGH----PGMPGPP 620 Query: 470 AVQGIANE--DAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQG 518 + G+ A++G + + G + + P G A G Sbjct: 621 GIPGLPGRPGQAINGKDGDRGSPGAPGEAGRPGLPGPVGLPGFCEPAACLG 671 Score = 48.9 bits (115), Expect = 6e-05 Identities = 83/488 (17%), Positives = 138/488 (28%), Gaps = 35/488 (7%) Query: 67 GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126 G+ D + G G G A G D G E G+ Sbjct: 42 GVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVK 101 Query: 127 AVQGVANEDAVQG--------------VANEDAVQGIANEDAAHGIANEDAAQGIANEDA 172 G+ + G + E ++G + G + G Sbjct: 102 GQPGLPGPPGLPGPGFAGPPGPPGPVGLPGEIGIRGPKGDPGPDGPSGPPGPPGKPGRPG 161 Query: 173 AQDIAKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVAN 232 E +A + + G+ +QG+ +GI + QG G + Sbjct: 162 TIQ-GLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVGASG 220 Query: 233 EDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQG 292 E QG+ QG+ + G E HG V A G +G G Sbjct: 221 E---QGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAG 277 Query: 293 IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVAT---QGIA- 348 ++ GI + G G+ +D + G A + + QG+A Sbjct: 278 EKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAG 337 Query: 349 -----TEDVADGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIA 403 G E G+ G E +G + + G ++ + Sbjct: 338 VPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVG 397 Query: 404 K--PDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDA 461 + P G E GI G+ + + G + +G + G+ E Sbjct: 398 QPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPG---KTGPRGKVGDPGVAGLPGEKG 454 Query: 462 AQGIAHE---DAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQG 518 +G + E QG+ E G + + A GV RG+ + QG Sbjct: 455 EKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGRQG 514 Query: 519 IATEDVAD 526 + D D Sbjct: 515 VEGRDATD 522 Score = 45.4 bits (106), Expect = 7e-04 Identities = 94/532 (17%), Positives = 144/532 (27%), Gaps = 31/532 (5%) Query: 1136 GVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 1195 GV D + G G G A D G D G E GI Sbjct: 42 GVPGSDGIDGDNGPPGKAGPPGPKGEPGKAGPDGPDGKPGIDGLTGAKGEPGPMGIPGVK 101 Query: 1196 AVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVA 1255 G+ G+ A P G+ E+ +G + DG + G Sbjct: 102 GQPGLP---GPPGLPGPGFAGPPGPPGPV-GLPGEIGIRGPKGDPGPDGPSGPPGPPGKP 157 Query: 1256 N--------EVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQG 1307 E +A + + G+ QG+ +GI + QG G Sbjct: 158 GRPGTIQGLEGSADFLCPTNCPPGMKGPPGLQGVKGHAGKRGILGDPGHQGKPGPKGDVG 217 Query: 1308 VANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDA 1367 + E QG+ QG+ + G E HG A G + Sbjct: 218 ASGE---QGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPG 274 Query: 1368 AQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIAN 1427 G ++ GI G G+ +D G G A + G Sbjct: 275 RAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQG 334 Query: 1428 EDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHG 1487 G G E QG+ G E +G + G + G Sbjct: 335 LAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERG 394 Query: 1488 VANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVA 1547 + P +G QG+ G + G + G+ E Sbjct: 395 PVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKG 454 Query: 1548 VHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIA 1607 G + E +G GV E G + A Q P G+A Sbjct: 455 EKGESGEPGPKG------QQGVRGEPGYPGPSGD-------AGAPGVQGYPGPPGPRGLA 501 Query: 1608 NEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQG 1659 + + QG+ +DA +VA + ++ A ++ + A G Sbjct: 502 GN---RGVPGQPGRQGVEGRDATDQHIVDVALKMLQEQLAEVAVSAKREALG 550 Score = 45.4 bits (106), Expect = 7e-04 Identities = 61/333 (18%), Positives = 91/333 (27%), Gaps = 15/333 (4%) Query: 56 DIANEDADAAHGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVAN 115 D ++ G QG+ QG+ G E HG A G Sbjct: 203 DPGHQGKPGPKGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATG 262 Query: 116 EVAAQGVANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQD 175 +G G ++ G+ + G GI +D G Sbjct: 263 PPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPG------ 316 Query: 176 IAKEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDA 235 K A Q A + + G V G G E QG+ G E Sbjct: 317 -MKGSAGQ--AGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPG 373 Query: 236 VQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAH 295 +G + G + +G + G G QG+ +G Sbjct: 374 PRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPG 433 Query: 296 EDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADG 355 + +G + V G+ E G + E P G+ E G + + A G Sbjct: 434 KTGPRGKVGDPGVAGLPGEKGEKGESGEPG------PKGQQGVRGEPGYPGPSGDAGAPG 487 Query: 356 IANEDAAHGVAKEVTAHGVANEDAVQGVVNEDA 388 + G GV + QGV DA Sbjct: 488 VQGYPGPPGPRGLAGNRGVPGQPGRQGVEGRDA 520 Score = 44.7 bits (104), Expect = 0.001 Identities = 67/382 (17%), Positives = 109/382 (28%), Gaps = 11/382 (2%) Query: 1568 GVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQ 1627 G+ +QGV ++ + Q P G + E I QGI Sbjct: 181 GMKGPPGLQGVKGHAGKRGILG-DPGHQGKPGPKGDVGASGE---QGIPGPPGPQGIRGY 236 Query: 1628 DAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGV 1687 G E HG G +G G ++ GI + G Sbjct: 237 PGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGPPGRAGEKGDEGSPGIRGPQGITGP 296 Query: 1688 AKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAA 1747 G+ +D G G A + G V G G E Sbjct: 297 KGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGHQGLAGVPGQPGTKGGPGDQGEPGP 356 Query: 1748 HGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANE 1807 G+ G E +G + + G + P +G Sbjct: 357 QGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGERGPVGQPGPQGRQGPKGEQGPPGI 416 Query: 1808 VAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGV 1867 QG+ G P + G + G+ E +G + E +G + ++G Sbjct: 417 PGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGEKGEKGESGEPGPKG---QQGVRGE 473 Query: 1868 ANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAV 1927 G A VQG G+A +G+ + Q + DA + A+ Sbjct: 474 PGYPGPSGDAGAPGVQGYPGPPGPRGLAGN---RGVPGQPGRQGVEGRDATDQHIVDVAL 530 Query: 1928 QGIANQDAAQGI-AKEDAVQGI 1948 + + Q A + AK +A+ + Sbjct: 531 KMLQEQLAEVAVSAKREALGAV 552 Score = 44.3 bits (103), Expect = 0.001 Identities = 54/310 (17%), Positives = 87/310 (28%), Gaps = 12/310 (3%) Query: 946 QGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHK 1005 +G G+ QG+ G E HG G +G Sbjct: 213 KGDVGASGEQGIPGPPGPQGIRGYPGMAGPKGETGPHGYKGMVGAIGATGPPGEEGPRGP 272 Query: 1006 DAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAA------QGIANEVAAHGISKE 1059 G ++ + GI G GI +D +G A + G Sbjct: 273 PGRAGEKGDEGSPGIRGPQGITGPKGATGPPGINGKDGTPGTPGMKGSAGQAGQPGSPGH 332 Query: 1060 DAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQ-- 1117 + G+ + +G + G G ++ G E+ G+ + Q Sbjct: 333 QGLAGVPGQPGTKGGPGDQGEPGPQGLPGFSGPPGKEGEPGPRGEIGPQGIMGQKGDQGE 392 Query: 1118 -GVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANE 1176 G + QG QG QG+ G + G + G+ E Sbjct: 393 RGPVGQPGPQGRQGPKGEQGPPGIPGPQGLPGVKGDKGSPGKTGPRGKVGDPGVAGLPGE 452 Query: 1177 DAAQGIAHE---DAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAA 1233 +G + E QG+ E G + + A GV RG+ + Sbjct: 453 KGEKGESGEPGPKGQQGVRGEPGYPGPSGDAGAPGVQGYPGPPGPRGLAGNRGVPGQPGR 512 Query: 1234 QGIATEDVAD 1243 QG+ D D Sbjct: 513 QGVEGRDATD 522 >gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] Length = 1073 Score = 57.0 bits (136), Expect = 2e-07 Identities = 121/679 (17%), Positives = 191/679 (28%), Gaps = 59/679 (8%) Query: 893 EGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANED 952 +G +E +A + T+ AD A A I + A + + + ED G+ + Sbjct: 209 KGTGHEFSA-ALGTQGPADQRADARASCILAAKTAPGLKQLNGEPGERGED---GLPGKP 264 Query: 953 AAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIA 1012 G E G E G+ GV E QG E+ + G+ +G A Sbjct: 265 GLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEA 324 Query: 1013 NEDAAHGIANEVAA----------HGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAV 1062 G+ + G E G+ E QG E+ G + Sbjct: 325 GPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGA 384 Query: 1063 QGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANE 1122 +G A G A A G G G+ G E G Sbjct: 385 KGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGS 444 Query: 1123 DAVQGVANEVEVQGVAH--------EDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIA 1174 G + G+ E ++G G + A GI ++G Sbjct: 445 PGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRG-- 502 Query: 1175 NEDAAQGIAHEDAVQGIANEDAV---HGVAKEVAAHGVANEDAAHAIAKPDAARGIANEV 1231 D G+A G + G+ G A D ++ P +A +V Sbjct: 503 --DPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDV 560 Query: 1232 AAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIA 1291 D G G + G + +G E G+ GIA Sbjct: 561 C------NDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLP---GPPGIA 611 Query: 1292 NEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQ 1351 +QG +G EV +G V G G D Sbjct: 612 GPQGSQG---------------ERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIA 656 Query: 1352 GIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEV 1411 G A Q ++ G + GI E+ +G D G E G Sbjct: 657 GAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEG---RDGKPGPPGEPGKAGEPGLP 713 Query: 1412 EVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIA 1471 +G +G + A G E A G+ + +G+ +D G QG Sbjct: 714 GPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQ---EGLPGKDGDTGPTGPQGPQGPR 770 Query: 1472 NEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAH 1531 +G G + + + G+ + +G E G+ ++ Sbjct: 771 GPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVP 830 Query: 1532 GVANEVAAQGIANEVAVHG 1550 G E +G + + G Sbjct: 831 GKPGEPGFKGERGDPGIKG 849 Score = 56.6 bits (135), Expect = 3e-07 Identities = 118/648 (18%), Positives = 199/648 (30%), Gaps = 47/648 (7%) Query: 769 VQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVAN 828 + G E G+ + ++G E G E G+ GV E QG Sbjct: 248 LNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKG 307 Query: 829 EDAVHGVANEDAAQGVAKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAH 888 E + G+ + +G A G + G + H + E + Sbjct: 308 ELGLPGLKGDRGEKGEA------GPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLP 361 Query: 889 GIAN-EGVANEVAAQGIATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQG 947 G +G E+ QG A G ++ AHG A A A G Sbjct: 362 GEPGLQGRPGELGPQGPTGPPGAKG--QEGAHG------APGAAGNPGAPGHVGAPGPSG 413 Query: 948 VANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDA 1007 A G+ G E A G G + G+ +G + Sbjct: 414 PPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPG 472 Query: 1008 IQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIAN 1067 ++G G + A GI ++G D G+A G + G Sbjct: 473 LRGSPGLPGPLGTKGDRGAPGIPGSPGSRG----DPGIGVAGPPGPSGPPGDKGSPG--- 525 Query: 1068 EDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQG 1127 ++G+ QG A D + + + ++ +AK+V D G + G Sbjct: 526 ---SRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVC------NDCPPGPPGLPGLPG 576 Query: 1128 VANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDA 1187 + V G + +G E G+ GIA +QG E A G + Sbjct: 577 FKGDKGVPGKPGREGTEGKKGEAGPPGLP---GPPGIAGPQGSQG---ERGADGEVGQKG 630 Query: 1188 VQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIAN 1247 QG V G G D A P +G + G GI Sbjct: 631 DQG---HPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPG 687 Query: 1248 EDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQG 1307 E+ G + G + G+ + A+G +G + A G E G Sbjct: 688 EEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARG---PPGFKGHTGDSGAPGPRGESGAMG 744 Query: 1308 VANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDA 1367 + ++ + G + G +G ++ + G E G + ++ E+ Sbjct: 745 LPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSK---GENG 801 Query: 1368 AQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQG 1415 + G+ +G E +G+ ++ V G E +G + ++G Sbjct: 802 SPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKG 849 Score = 55.8 bits (133), Expect = 5e-07 Identities = 118/682 (17%), Positives = 197/682 (28%), Gaps = 42/682 (6%) Query: 924 EEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHG 983 ++ AQ + + + A Q + H + QG A++ A + A Sbjct: 182 DQGAQGACGRGNTSVLPSSVAPQCSMPKGTGHEFSAALGTQGPADQRADARASCILAAKT 241 Query: 984 VANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDA 1043 + G E G+ K ++G E G E G+ G+ E Sbjct: 242 APGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKG 301 Query: 1044 AQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAA----------QGIAHEDAVQGIA 1093 QG E+ G+ + +G A G+ + QG E G+ Sbjct: 302 DQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLP 361 Query: 1094 NEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAH 1153 E + G E+ G +G G A G G A Sbjct: 362 GEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAP 421 Query: 1154 GIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANED 1213 G+ G E A G G + G+ G E G Sbjct: 422 GLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPGLRGSPGLP 480 Query: 1214 AAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIA 1273 A GI ++G D G+A G + + G +G+ Sbjct: 481 GPLGTKGDRGAPGIPGSPGSRG----DPGIGVAGPPGPSGPPGDKGSPGS------RGLP 530 Query: 1274 NEDAAQGIAKEDAVQGIANEDAAQGIAKE---DPVQGVANEDPIQGVANEVEVQGVAHED 1330 QG A D + + + +AK+ D G + G + V G + Sbjct: 531 GFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGRE 590 Query: 1331 AVQGIANE------DAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANED 1384 +G E GIA +QG D + G+ G Sbjct: 591 GTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPP 650 Query: 1385 AAQGI---AKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAH 1441 A GI A +QG ++ G + G+ E+ +G + G + Sbjct: 651 GADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEP 710 Query: 1442 GIANEDAA------QGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAH 1495 G+ + A +G + A G E G+ ++ + G + G Sbjct: 711 GLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPR 770 Query: 1496 AIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIED 1555 + + G E G + G E+ + G+ + +G E GV ++ Sbjct: 771 GPPGKNGSPGSPGEPGPSGTPGQ---KGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKE 827 Query: 1556 AVQGVVKEVTAHGVANEDAVQG 1577 V G E G + ++G Sbjct: 828 GVPGKPGEPGFKGERGDPGIKG 849 Score = 53.5 bits (127), Expect = 2e-06 Identities = 153/866 (17%), Positives = 238/866 (27%), Gaps = 70/866 (8%) Query: 1391 KEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDA-- 1448 + DP + V + QG + A Q + H + + G A++ A Sbjct: 174 RTDPWENV--DQGAQGACGRGNTSVLPSSVAPQCSMPKGTGHEFSAALGTQGPADQRADA 231 Query: 1449 -AQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIA 1507 A I A G+ + G ED + G G+ E +A +G A Sbjct: 232 RASCILAAKTAPGLKQLNGEPGERGEDGLPGKP------GLRGEIGEQGLAGRPGEKGEA 285 Query: 1508 NEVATQGIATEDVADGIANEDAAHGVANEVAAQGIAN---EVAVHGVAIEDAVQGVVKEV 1564 G G+ E G E+ G+ E G A + G Sbjct: 286 GLPGAPGFP------GVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLF 339 Query: 1565 TAH-------GVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIAN 1617 T H G E G+ E L E Q P A G A A Sbjct: 340 TPHPRMPGEQGPKGEKGDPGLPGEPGLQGR-PGELGPQGPTGPPGAKGQEGAHGAPGAAG 398 Query: 1618 KDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQG 1677 A G G V A G+ G E A G G + G Sbjct: 399 NPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPG 458 Query: 1678 IANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDA 1737 + G E G G + G+ +G D G+A Sbjct: 459 LPGPPG-KGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRG----DPGIGVAGPPG 513 Query: 1738 AHGITNEVAA---HGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHA 1794 G + + G+ QG A D + + + ++ +AK+V Sbjct: 514 PSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCN----------- 562 Query: 1795 IAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDA 1854 D G G + G P + G E G+ GIA Sbjct: 563 ----DCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLP---GPPGIAGPQG 615 Query: 1855 AQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAN 1914 +QG +G EV +G V G G D G A Q Sbjct: 616 SQG------ERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPG 669 Query: 1915 EDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQG 1974 ++ G + GI ++ +G D G E G G +G Sbjct: 670 KEGPPGPQGPSGLPGIPGEEGKEG---RDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKG 726 Query: 1975 IANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDV 2034 + A G E G+ ++ + G + P RG + + G E Sbjct: 727 HTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPG 786 Query: 2035 ADGIANEDAAHGVANEDAAQAIAKPDAAHGIANE-GIATEDVADGIAEDAVQGITNEEAA 2093 G + + G P G E G+ ++ G + G E Sbjct: 787 PSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPG--KPGEPGFKGERGD 844 Query: 2094 QAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANE 2153 I G + G+ G+ G V G + G+ E Sbjct: 845 PGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGE 904 Query: 2154 VAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGV 2213 + + + ++E + +A+ A A ++QG G +D G Sbjct: 905 SPSMETLRRLIQEELGKQLETR-LAYLLAQMPPAYMKSSQG---RPGPPGPPGKDGLPGR 960 Query: 2214 ANEVAAQGVANEDAAQGVANEVAVHG 2239 A + G + +G + + G Sbjct: 961 AGPMGEPGRPGQGGLEGPSGPIGPKG 986 Score = 50.1 bits (118), Expect = 3e-05 Identities = 124/691 (17%), Positives = 202/691 (29%), Gaps = 49/691 (7%) Query: 125 EDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQD 184 + QG + + A Q + H + QG A++ A + AA+ Sbjct: 182 DQGAQGACGRGNTSVLPSSVAPQCSMPKGTGHEFSAALGTQGPADQRADARASCILAAKT 241 Query: 185 IANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVE 244 G E G+ + +G E + G E G+ GV E Sbjct: 242 APGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKG 301 Query: 245 VQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAA-QGIANEDAAQGIAHEDAVQGIA 303 QG E + G+ + G G+ + QG E G+ Sbjct: 302 DQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLP 361 Query: 304 NEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAH 363 E + G E+ G A + AHG G A G + + Sbjct: 362 GEPGLQGRPGELGPQGPTGPPGAKG---QEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSV 418 Query: 364 GVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKP-DAAHGIANEVAAHGIAN 422 G G E +G E+ G V A P G E G Sbjct: 419 GAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPG 478 Query: 423 EDAAQGIANEVAAHGI-----SKEDAVQGIA------------NEDAAQGIAHEDAAQGI 465 G + A GI S+ D G+A ++G+ QG Sbjct: 479 LPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGP 538 Query: 466 AHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVA 525 A D + + + ++ +AK+V + +G+ + +G + Sbjct: 539 AGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGE 598 Query: 526 DGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAH-GIANEVATQGIATEDVADGIAN 584 G G+A + G D K D H G+ + G ADGIA Sbjct: 599 AGPPGLPGPPGIAGPQGSQGERGAD-GEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIA- 656 Query: 585 EDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQG 644 G A + G ++ G + G+ E+ +G G G Sbjct: 657 -----GAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEG------RDGKPGPPGEPG 705 Query: 645 VVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEV 704 E L G + P G + A G E A G+ ++ G + Sbjct: 706 KAGEPGLPG-------PEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDT 758 Query: 705 AAHGISKEDAVQGIANEDAAQGIAHE------DAVQGIANEDAVHGVAKEVAAHGVANED 758 G +G ++ + G E +G E+ G+ + G E Sbjct: 759 GPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEP 818 Query: 759 PVQGVANEDVVQGVANEVEVQGIAHEDAVQG 789 +GV ++ V G E +G + ++G Sbjct: 819 GEKGVPGKEGVPGKPGEPGFKGERGDPGIKG 849 Score = 48.1 bits (113), Expect = 1e-04 Identities = 124/678 (18%), Positives = 186/678 (27%), Gaps = 65/678 (9%) Query: 337 GIANEVATQGIATEDVADGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVAN- 395 G+ E+ QG+A G A A G GV E QG E L G+ + Sbjct: 265 GLRGEIGEQGLAGRPGEKGEAGLPGAPGFP------GVRGEKGDQGEKGELGLPGLKGDR 318 Query: 396 -EDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQ 454 E A P G + H QG E G+ E +QG E Q Sbjct: 319 GEKGEAGPAGPPGLPGTTSLFTPH--PRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQ 376 Query: 455 GIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEV 514 G A+G ++ HG A G A A G V Sbjct: 377 GPTGPPGAKG------------QEGAHG------APGAAGNPGAPGHVGAPGPSGPPGSV 418 Query: 515 AAQGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDA-----------AHG 563 A G+ DG E G G + A + P + G Sbjct: 419 GAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPG 478 Query: 564 IANEVATQGI-----------ATEDVADGIANEDAAHGVANEVAV---HGVAIEDAVQGV 609 + + T+G + D G+A G + G+ QG Sbjct: 479 LPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGP 538 Query: 610 ANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDA 669 A D + + + +AK+V + G+ GV K Sbjct: 539 AGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGE 598 Query: 670 AHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAH 729 A G GIA +QG +G EV G V G G Sbjct: 599 A-GPPGLPGPPGIAGPQGSQG------ERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPG 651 Query: 730 EDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQG 789 D + G A + G + G + G+ E+ +G + G + G Sbjct: 652 ADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPG 711 Query: 790 IANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVT 849 + + A G G + A G E A G+ ++ + G + G Sbjct: 712 LPGPEGARG---PPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQG 768 Query: 850 AHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDV 909 G ++ G E G + + P + G E +G+ ++ Sbjct: 769 PRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEG 828 Query: 910 ADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANE 969 G K G E I + G+ G+ G Sbjct: 829 VPG--KPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGP 886 Query: 970 VAAQGVANEDAVHGVANE 987 V G + G+ E Sbjct: 887 VGPPGPPGQPGFPGLRGE 904 Score = 46.6 bits (109), Expect = 3e-04 Identities = 102/568 (17%), Positives = 153/568 (26%), Gaps = 45/568 (7%) Query: 1721 QGVAHEDAV----QGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHS 1776 +G HE + QG A++ A + +AA G E G+ + + Sbjct: 209 KGTGHEFSAALGTQGPADQRADARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRG 268 Query: 1777 VAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVA 1836 E G E + G+ E QG E G+ + G A Sbjct: 269 EIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAG 328 Query: 1837 AHGISKEDAV----------QGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIA 1886 G+ ++ QG E G+ E +QG E+ QG +G Sbjct: 329 PPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQE 388 Query: 1887 NEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQ 1946 A G A A G A G+ G + A G Sbjct: 389 GAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPV 448 Query: 1947 GIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANED 2006 G + A G+ G E +G G + GI G D Sbjct: 449 GPRGDPGAPGLPGP-PGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRG----D 503 Query: 2007 AAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPD----AA 2062 +A P G + + G + G+ G A D ++ P A Sbjct: 504 PGIGVAGPPGPSGPPGDKGSPG------SRGLPGFPGPQGPAGRDGLSSLLSPGDINLLA 557 Query: 2063 HGIANEGIATEDVADGI----AEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEV 2118 + N+ G+ + V G E + + G+ G+ Sbjct: 558 KDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLP---GPPGIAGPQ 614 Query: 2119 AAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIA 2178 +QG G EV G G G D + G A +QG Sbjct: 615 GSQG------ERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSP 668 Query: 2179 HKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVH 2238 K+ G G+ E G D G E G +G Sbjct: 669 GKEGPPGPQGPSGLPGIPGE---EGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFK 725 Query: 2239 GVANEDAARHMAKEDAAQGIANEDAAHG 2266 G + A E A G+ ++ G Sbjct: 726 GHTGDSGAPGPRGESGAMGLPGQEGLPG 753 Score = 43.5 bits (101), Expect = 0.002 Identities = 91/531 (17%), Positives = 144/531 (27%), Gaps = 33/531 (6%) Query: 1719 EVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVA 1778 ++ G E G+ + G E G E G+ G+ E Sbjct: 247 QLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEK 306 Query: 1779 KEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAH 1838 E+ G+ + A P G+ T + P G E Sbjct: 307 GELGLPGLKGDRGEKGEAGPAGPPGLPG--------TTSLFTPHPRMPGEQGPKGEKGDP 358 Query: 1839 GISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANED 1898 G+ E +QG E QG +G G A G G Sbjct: 359 GLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSV 418 Query: 1899 AAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIA 1958 A G+ E A G G A G+ +G E +G Sbjct: 419 GAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPG-KGKDGEPGLRGSP 477 Query: 1959 NEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAAR 2018 G + A GI ++G D G+A G + + +R Sbjct: 478 GLPGPLGTKGDRGAPGIPGSPGSRG----DPGIGVAGPPGPSGPPGDKGS------PGSR 527 Query: 2019 GIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGI----ANEGIATED 2074 G+ QG A D + + + +A + P G+ ++G+ + Sbjct: 528 GLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKP 587 Query: 2075 VADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAH-GVA 2133 +G +G E + G +G EV +G D H GV Sbjct: 588 GREG-----TEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKG----DQGHPGVP 638 Query: 2134 NEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQ 2193 + G A G+A G+ +G G+ +G D Sbjct: 639 GFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKP 698 Query: 2194 GVANEVAAHGVANEDAAQGVANEVAAQGVANEDAAQGVANEVAVHGVANED 2244 G E G +G +G + A G E G+ ++ Sbjct: 699 GPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQE 749 Score = 38.9 bits (89), Expect = 0.061 Identities = 45/262 (17%), Positives = 79/262 (30%), Gaps = 12/262 (4%) Query: 76 GVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANED 135 G+A +QG G EV G G G D + G A Sbjct: 609 GIAGPQGSQG------ERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPP 662 Query: 136 AVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQGIS 195 +QG ++ G GI E+ +G + + + + A+G Sbjct: 663 GIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARG-- 720 Query: 196 KEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQ 255 +G + A G E G+ ++ + G + G +G ++ Sbjct: 721 -PPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSP 779 Query: 256 GIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEV 315 G E G + + G E+ + G+ +G E +G+ ++ V G E Sbjct: 780 GSPGEPGPSGTPGQKGSKG---ENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEP 836 Query: 316 AAHGVANEDAAHAIAKPDAAHG 337 G + P G Sbjct: 837 GFKGERGDPGIKGDKGPPGGKG 858 Score = 33.9 bits (76), Expect = 2.0 Identities = 51/308 (16%), Positives = 81/308 (26%), Gaps = 6/308 (1%) Query: 84 QGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEDAVQGVANE 143 +GV + G + G G+A +QG D G + GV Sbjct: 581 KGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGF 640 Query: 144 DAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIANEDAAQGISKEDAVQGI 203 G A GIA GI + + +G D G Sbjct: 641 MGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGP 700 Query: 204 ANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAA 263 E G +G +G + G E G+ + +G+ +D Sbjct: 701 PGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQ---EGLPGKDGD 757 Query: 264 HGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANE 323 G T G G G + +G E+ G+ + G E Sbjct: 758 TGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGE 817 Query: 324 DAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAKEVTAHGVANEDAVQGV 383 + G+ + G E GI + G + G+ G+ Sbjct: 818 PGEKGV---PGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGL 874 Query: 384 VNEDALHG 391 + L G Sbjct: 875 MGPQGLPG 882 Score = 33.5 bits (75), Expect = 2.6 Identities = 45/261 (17%), Positives = 78/261 (29%), Gaps = 18/261 (6%) Query: 75 QGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQ---GVANEVAAQGVANEDAVQGV 131 +GV + +G + G G+A +Q G EV +G V G Sbjct: 581 KGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGF 640 Query: 132 ---------ANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAA 182 D + G A +QG ++ G GI E+ + D Sbjct: 641 MGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEG---RDGK 697 Query: 183 QDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANE 242 E G +G +G + G E G+ ++ + G + Sbjct: 698 PGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGD 757 Query: 243 VEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGI 302 G +G ++ + G E G + ++G E+ + G+ +G Sbjct: 758 TGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKG---ENGSPGLPGFLGPRGP 814 Query: 303 ANEDAVHGVAKEVAAHGVANE 323 E GV + G E Sbjct: 815 PGEPGEKGVPGKEGVPGKPGE 835 >gi|18780273 collagen, type XXI, alpha 1 precursor [Homo sapiens] Length = 957 Score = 56.6 bits (135), Expect = 3e-07 Identities = 66/331 (19%), Positives = 106/331 (32%), Gaps = 21/331 (6%) Query: 1028 GIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHED 1087 G+ G +D G G+ +QG A+G+ G + Sbjct: 461 GLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQG------ARGLPGYKGEPGRDGDK 514 Query: 1088 AVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIA 1147 +G+ +HG+ G + G + +G +G A + G A Sbjct: 515 GDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKG------EKGNAGFPGLPGPA 568 Query: 1148 NEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAH 1207 E HG + + G E + G +D +G E + G + G E+ Sbjct: 569 GEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRG---EPGIPGFPGNRGLMGQKGEIGPP 625 Query: 1208 GVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKED 1267 G + A + + G + G GI A G+ E A G E Sbjct: 626 GQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEP 685 Query: 1268 ---AVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQ 1324 + GI + +G E +QG E+ QGI + +QG +G E V+ Sbjct: 686 GYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVR 745 Query: 1325 GV---AHEDAVQGIANEDAAHGIANEDAAQG 1352 G E V G+ G + QG Sbjct: 746 GAIGSKGESGVDGLMGPAGPKGQPGDPGPQG 776 Score = 47.4 bits (111), Expect = 2e-04 Identities = 65/345 (18%), Positives = 100/345 (28%), Gaps = 42/345 (12%) Query: 1005 KDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQG 1064 K QGIA G A G+ G + +G+ HG+ G Sbjct: 477 KPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMG 536 Query: 1065 IANEDAAQGIANEDAAQGIAHEDAVQGI---ANEDAVHGVAKEVAAHGVANEDPVQGVAN 1121 + + G + A+G G+ A E HG + + G E G Sbjct: 537 AKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPG 596 Query: 1122 EDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQG 1181 +D +G E + G G E+ G + A G+ + G Sbjct: 597 QDGTRG------------EPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNG 644 Query: 1182 IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDV 1241 + G G+ A G+ E A G E G+ Sbjct: 645 SPGQPGTPGSKGSKGEPGIQGMPGASGLKGE---------PGATGSPGEPGYMGLP---- 691 Query: 1242 ADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAK 1301 G+ + G E +QG E+ QGI + +QG +G Sbjct: 692 -----------GIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKG 740 Query: 1302 EDPVQGV---ANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHG 1343 E V+G E + G+ +G + QG D G Sbjct: 741 EPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPG 785 Score = 47.4 bits (111), Expect = 2e-04 Identities = 75/384 (19%), Positives = 117/384 (30%), Gaps = 30/384 (7%) Query: 942 EDAAQGVANEDAAHGVANEDAAQGVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQG 1001 E A+G +G +G A G A E HG G E G Sbjct: 534 EMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPG 593 Query: 1002 IAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDA 1061 +D +G E G G E G + A G+ + ++G + Sbjct: 594 APGQDGTRG---EPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPG 650 Query: 1062 VQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDA---VHGVAKEVAAHGVANEDPVQG 1118 G GI A G+ E G E + G+ + G E +QG Sbjct: 651 TPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQG 710 Query: 1119 VANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDA 1178 E+ QG+ + QG+ +G E G+ + + G + D G A Sbjct: 711 QKGENGRQGIPGQ---QGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKG 767 Query: 1179 AQGIAHEDAVQGI-------ANEDAVHGVAKEV---------AAHGVANEDAAHAIAKPD 1222 G G+ +E + V +V + + N D H +++ Sbjct: 768 QPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCD--HCLSQ-H 824 Query: 1223 AARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIA 1282 + GI G G+ D G+ G+ + G E +QG Sbjct: 825 GSPGIPGPPGPIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFG 884 Query: 1283 --KEDAVQGIANEDAAQGIAKEDP 1304 E G + GI+KE P Sbjct: 885 YPGEQGPPGPPGPEGPPGISKEGP 908 Score = 46.6 bits (109), Expect = 3e-04 Identities = 68/337 (20%), Positives = 100/337 (29%), Gaps = 24/337 (7%) Query: 1623 GIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 1682 G QD G G+ +QG +G D +G + + G Sbjct: 470 GQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKG---DRGLPGFPGLH 526 Query: 1683 AVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIT 1742 + G E+ A G G +G A + G A E G + G Sbjct: 527 GMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFK 586 Query: 1743 NEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAAR 1802 E + G +D +G E + G + E+ G + A + + Sbjct: 587 GEAGSPGAPGQDGTRG---EPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSN 643 Query: 1803 GIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDA---VQGIANEDAAQGIA 1859 G + G GI A G+ E A G E + GI + +G Sbjct: 644 GSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQ 703 Query: 1860 KEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQ 1919 E IQG E QG+ + +QG A G E G+ A Sbjct: 704 GEKGIQGQKGENGRQGIPGQQGIQG---HHGAKGERGEKGEPGVR------------GAI 748 Query: 1920 GISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQG 1956 G E V G+ +G + QG D G Sbjct: 749 GSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPG 785 Score = 45.4 bits (106), Expect = 7e-04 Identities = 60/312 (19%), Positives = 91/312 (29%), Gaps = 25/312 (8%) Query: 517 QGIATEDVADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATE 576 QGIA G G+ G + + HG+ G + Sbjct: 481 QGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGD 540 Query: 577 DVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGV 636 + G + A G G+ G A E HG + G E + G Sbjct: 541 KGSPGFYGKKGAKGEKGNAGFPGLP------GPAGEPGRHGKDGLMGSPGFKGEAGSPGA 594 Query: 637 ANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDA 696 +D +G E + G N G E+ G + A G+ Sbjct: 595 PGQDGTRG---EPGIPGFPGNRGLM----------GQKGEIGPPGQQGKKGAPGMPGLMG 641 Query: 697 AQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDA---VHGVAKEVAAHG 753 + G + G GI A G+ E G E + G+ + G Sbjct: 642 SNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKG 701 Query: 754 VANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDA 813 E +QG E+ QG+ + QGI +G E G+ + + G + D Sbjct: 702 NQGEKGIQGQKGENGRQGIPGQ---QGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDG 758 Query: 814 AQGVANEDAAQG 825 G A G Sbjct: 759 LMGPAGPKGQPG 770 Score = 43.9 bits (102), Expect = 0.002 Identities = 57/307 (18%), Positives = 83/307 (27%), Gaps = 9/307 (2%) Query: 974 GVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANED 1033 G + G+A V G +G+ G + G+ HG+ Sbjct: 473 GQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSK 532 Query: 1034 AAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIA 1093 G + + G + A G +G A G A E G +D + G Sbjct: 533 GEMGAKGDKGSPGFYGKKGAKG------EKGNAGFPGLPGPAGEPGRHG---KDGLMGSP 583 Query: 1094 NEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAH 1153 G G E + G + G E+ G + G+ ++ Sbjct: 584 GFKGEAGSPGAPGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSN 643 Query: 1154 GIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANED 1213 G + G GI A G+ E G E G+ G Sbjct: 644 GSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQ 703 Query: 1214 AAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIA 1273 I G QGI A G E GV + + G S D + G A Sbjct: 704 GEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPA 763 Query: 1274 NEDAAQG 1280 G Sbjct: 764 GPKGQPG 770 Score = 43.5 bits (101), Expect = 0.002 Identities = 55/302 (18%), Positives = 84/302 (27%), Gaps = 18/302 (5%) Query: 946 QGVANEDAAHGVANEDAAQGVA---------NEVAAQGVANEDAVHGVANEDAVQGVANE 996 QG+A G A+G+ + +G+ +HG+ G + Sbjct: 481 QGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGD 540 Query: 997 VEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGI 1056 G K +G G+ G +D G G G Sbjct: 541 KGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGT 600 Query: 1057 SKEDAVQGIANEDAAQGIANE---DAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANE 1113 E + G G E QG + G+ + G + G E Sbjct: 601 RGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGE 660 Query: 1114 DPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGI 1173 +QG+ ++G G + GI + G E G E+ QGI Sbjct: 661 PGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGI 720 Query: 1174 ANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAA 1233 + QG +G E V G A G E + P +G + Sbjct: 721 PGQQGIQGHHGAKGERGEKGEPGVRG------AIGSKGESGVDGLMGPAGPKGQPGDPGP 774 Query: 1234 QG 1235 QG Sbjct: 775 QG 776 Score = 43.1 bits (100), Expect = 0.003 Identities = 55/321 (17%), Positives = 91/321 (28%), Gaps = 6/321 (1%) Query: 1702 VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAH 1761 +QG + + G G + QGIA G A G+ G Sbjct: 453 LQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDG 512 Query: 1762 EDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADG 1821 + +G+ +H + G + + A+G G+ G Sbjct: 513 DKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPG 572 Query: 1822 IPNEDA---AHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAH 1878 +D + G E + G +D +G E G + G E+ G Sbjct: 573 RHGKDGLMGSPGFKGEAGSPGAPGQDGTRG---EPGIPGFPGNRGLMGQKGEIGPPGQQG 629 Query: 1879 EDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQG 1938 + G+ ++G + G I A G+ E G + G Sbjct: 630 KKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMG 689 Query: 1939 IAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDA 1998 + +G +GI + +G QGI A+G E G+ Sbjct: 690 LPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIG 749 Query: 1999 VHGVANEDAAHAIAKPDAARG 2019 G + D A P G Sbjct: 750 SKGESGVDGLMGPAGPKGQPG 770 Score = 42.4 bits (98), Expect = 0.006 Identities = 90/517 (17%), Positives = 150/517 (29%), Gaps = 42/517 (8%) Query: 1305 VQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAN 1364 +QG + + G G + QGIA G A+G+ Sbjct: 453 LQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDG 512 Query: 1365 EDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQG 1424 + +G+ + G+ G + G + +G +G A + G Sbjct: 513 DKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKG------EKGNAGFPGLPG 566 Query: 1425 IANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVA 1484 A E HG + + G E + G +D +G E + G + G E+ Sbjct: 567 PAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRG---EPGIPGFPGNRGLMGQKGEIG 623 Query: 1485 AHGVANEDAAHAIAKPDAARGIANEVATQGIATEDVADGIANEDAAHGVANEVAAQGIAN 1544 G + A + + G + T G GI A G+ E A G Sbjct: 624 PPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPG 683 Query: 1545 EVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAH 1604 E G + G+ + G E +QG E+ + + H Sbjct: 684 EPGYMG------LPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQQGI-------QGHH 730 Query: 1605 GIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANED 1664 G E A G + G+ G + QG D G + Sbjct: 731 GAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGREFSE 790 Query: 1665 AAQGIAHEDAVQG----IANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEV 1720 D ++ + + ++ HG G + +G + Sbjct: 791 QFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEGPRG------L 844 Query: 1721 QGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAH--EDAVQGIANEDAVHSVA 1778 G+ D V G+ G+ G E +QG + E G + ++ Sbjct: 845 PGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGIS 904 Query: 1779 KE--VAAHGVANEDAAHAIAKPDAARGIANEVAAQGI 1813 KE G+ +D H KP GI + GI Sbjct: 905 KEGPPGDPGLPGKDGDH--GKP----GIQGQPGPPGI 935 Score = 42.4 bits (98), Expect = 0.006 Identities = 79/474 (16%), Positives = 131/474 (27%), Gaps = 17/474 (3%) Query: 1279 QGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANE 1338 QGIA V G A+G+ G + +G+ + G+ G + Sbjct: 481 QGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGD 540 Query: 1339 DAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGV 1398 + G + A+G + G +D + G G G Sbjct: 541 KGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGT 600 Query: 1399 ANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAA 1458 E + G + G E G + A G+ + ++G + G Sbjct: 601 RGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGE 660 Query: 1459 QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATE 1518 GI G+ E G E G+ +GI + G Sbjct: 661 PGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGI 720 Query: 1519 DVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGV 1578 GI A G E G+ + G E V G++ G + QG Sbjct: 721 PGQQGIQGHHGAKGERGEKGEPGVRGAIGSKG---ESGVDGLMGPAGPKGQPGDPGPQGP 777 Query: 1579 VNEDALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVA 1638 D +E + + + + + I N D +Q + GI Sbjct: 778 PGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHC---LSQHGSPGIPGPPG 834 Query: 1639 AHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVAN 1698 G + G+ D G+ G+ + G E G G Sbjct: 835 PIGPEGPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQG-------FGYPG 887 Query: 1699 EDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIAN 1752 E G + G++ E G + + G + GI + GI + Sbjct: 888 EQGPPGPPGPEGPPGISKE----GPPGDPGLPGKDGDHGKPGIQGQPGPPGICD 937 Score = 42.4 bits (98), Expect = 0.006 Identities = 54/292 (18%), Positives = 86/292 (29%), Gaps = 9/292 (3%) Query: 1117 QGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANE 1176 QG+A V G +G+ G + G+ HG+ G + Sbjct: 481 QGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGD 540 Query: 1177 DAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGI 1236 + G + +G G+ G A E H + G E + G Sbjct: 541 KGSPGFYGKKGAKGEKGNAGFPGLP------GPAGEPGRHGKDGLMGSPGFKGEAGSPGA 594 Query: 1237 ATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAA 1296 +D G G + G QG G+ + G + Sbjct: 595 PGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGS 654 Query: 1297 QGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANE 1356 +G E +QG+ ++G G + GI + G E QG E Sbjct: 655 KGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGE 714 Query: 1357 DAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVA 1408 + Q I + QGI +G E G+ +G + D + G A Sbjct: 715 NGRQGIPGQ---QGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPA 763 Score = 42.4 bits (98), Expect = 0.006 Identities = 60/317 (18%), Positives = 100/317 (31%), Gaps = 37/317 (11%) Query: 1919 QGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANE 1978 QGI+ V G A+G+ G + +G+ HG+ G + Sbjct: 481 QGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGD 540 Query: 1979 DAAQGIAHEDAVQGI---ANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVA 2035 + G + +G A + G A E H G + + G E + Sbjct: 541 KGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRH---------GKDGLMGSPGFKGEAGS 591 Query: 2036 DGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQA 2095 G +D G +P N G+ + E G ++ A Sbjct: 592 PGAPGQDGTRG-----------EPGIPGFPGNRGLMGQK-----GEIGPPGQQGKKGAPG 635 Query: 2096 IAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVA 2155 + ++G + G G+ A G+ E A G E G+ Sbjct: 636 MPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLP---- 691 Query: 2156 AQGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVAN 2215 G+ + +G E +QG ++ QGI + QG+ A G E GV Sbjct: 692 --GIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQ---QGIQGHHGAKGERGEKGEPGVRG 746 Query: 2216 EVAAQGVANEDAAQGVA 2232 + ++G + D G A Sbjct: 747 AIGSKGESGVDGLMGPA 763 Score = 42.0 bits (97), Expect = 0.007 Identities = 100/517 (19%), Positives = 152/517 (29%), Gaps = 76/517 (14%) Query: 734 QGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANE 793 QGIA V G + G+ + G E G + + G + G E Sbjct: 481 QGIAGTPGVPG------SPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGE 534 Query: 794 DAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVAKEVTAHGV 853 A G +G +G A G A E HG + G E + G Sbjct: 535 MGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGA 594 Query: 854 TNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGIATEDVADGI 913 +D +G E + G N + +G QG Sbjct: 595 PGQDGTRG---EPGIPGFPGNRGL------------MGQKGEIGPPGQQG---------- 629 Query: 914 AKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQGVANEVAAQ 973 K A G+ + Q G+ A G+ E A G E Sbjct: 630 -KKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYM 688 Query: 974 GVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEVAAHGIANED 1033 G+ +QG + QG + IQG E+ GI + GI Sbjct: 689 GLPG------------IQGKKGDKGNQG---EKGIQGQKGENGRQGIPGQ---QGIQGHH 730 Query: 1034 AAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIA 1093 A+G E G+ + + G E V G+ +G + QG D G Sbjct: 731 GAKGERGEKGEPGVRGAIGSKG---ESGVDGLMGPAGPKGQPGDPGPQGPPGLDGKPGRE 787 Query: 1094 -NEDAVHGVAKEV---------AAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAV 1143 +E + V +V + + N D + G + +G + Sbjct: 788 FSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPEG---PRGL 844 Query: 1144 QGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAH--EDAVQGIANEDAVHGVA 1201 G+ D G+ G+ G E +QG + E G + G++ Sbjct: 845 PGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGFGYPGEQGPPGPPGPEGPPGIS 904 Query: 1202 KE--VAAHGVANEDAAHAIAKPDAARGIANEVAAQGI 1236 KE G+ +D H KP GI + GI Sbjct: 905 KEGPPGDPGLPGKDGDH--GKP----GIQGQPGPPGI 935 Score = 42.0 bits (97), Expect = 0.007 Identities = 88/469 (18%), Positives = 139/469 (29%), Gaps = 37/469 (7%) Query: 67 GITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANED 126 G+ +QG +G D G G+ ++G E+ A+G Sbjct: 488 GVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKG---EMGAKGDKGSP 544 Query: 127 AVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQDIA 186 G +G A + G A E HG + G E + +D + Sbjct: 545 GFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTR--- 601 Query: 187 NEDAAQGISKEDAVQGIANE---DAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEV 243 E G + G E QG + G+ + G +G E Sbjct: 602 GEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEP 661 Query: 244 EVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIA 303 +QG+ ++G + G + GI + +G E QG E+ QGI Sbjct: 662 GIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENGRQGIP 721 Query: 304 NEDAV---HGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANED 360 + + HG E G A G+ +G + G D Sbjct: 722 GQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGPQGPPGLD 781 Query: 361 AAHGVAKEVTAHGVAN--EDAVQGVVNEDALHGVVANED------AAQAIAKPDAAHGIA 412 G +E + + D ++ + G + N D + I P G Sbjct: 782 GKPG--REFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCDHCLSQHGSPGIPGPPGPIGPE 839 Query: 413 NEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQ 472 G+ D G+ G+ + G E +QG G E Sbjct: 840 GPRGLPGLPGRDGVPGLVGVPGRPGVRGLKGLPGRNGEKGSQGF-------GYPGEQGPP 892 Query: 473 GIANEDAVHGVAKE--VAAHGVANKDAAHAIAKPDAARGIANEVAAQGI 519 G + G++KE G+ KD H KP GI + GI Sbjct: 893 GPPGPEGPPGISKEGPPGDPGLPGKDGDH--GKP----GIQGQPGPPGI 935 Score = 41.6 bits (96), Expect = 0.009 Identities = 68/334 (20%), Positives = 96/334 (28%), Gaps = 15/334 (4%) Query: 1073 GIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEV 1132 G+ G+ G +D G GV +QG + G E Sbjct: 452 GLQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARG---LPGYKGEP 508 Query: 1133 EVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIA 1192 G + + G G E+ A G G +G A + G A Sbjct: 509 GRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPA 568 Query: 1193 NEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAH 1252 E HG + + G E + D RG E G G E Sbjct: 569 GEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRG---EPGIPGFPGNRGLMGQKGEIGPP 625 Query: 1253 GVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANED 1312 G + A G+ G + G GI A G+ E G E Sbjct: 626 GQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEP 685 Query: 1313 PIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGIS 1372 G+ +QG + QG E G E+ QGI + Q I A+G Sbjct: 686 GYMGLPG---IQGKKGDKGNQG---EKGIQGQKGENGRQGIPGQ---QGIQGHHGAKGER 736 Query: 1373 KEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQG 1406 E G+ ++G + D + G A G Sbjct: 737 GEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPG 770 Score = 40.8 bits (94), Expect = 0.016 Identities = 50/250 (20%), Positives = 76/250 (30%), Gaps = 15/250 (6%) Query: 66 HGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGV---ANEDAAQGVANEVAAQGV 122 HG+ G + + G + A G G+ A E G + + G Sbjct: 526 HGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGF 585 Query: 123 ANEDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAA 182 E G +D +G E + G G E G + A + + Sbjct: 586 KGEAGSPGAPGQDGTRG---EPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGS 642 Query: 183 QDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANE 242 + G GI A G+ E G E G+ +QG + Sbjct: 643 NGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPG---IQGKKGD 699 Query: 243 VEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGI 302 QG E +QG E+ GI + GI A+G E G+ +G Sbjct: 700 KGNQG---EKGIQGQKGENGRQGIPGQ---QGIQGHHGAKGERGEKGEPGVRGAIGSKGE 753 Query: 303 ANEDAVHGVA 312 + D + G A Sbjct: 754 SGVDGLMGPA 763 Score = 40.4 bits (93), Expect = 0.021 Identities = 42/203 (20%), Positives = 60/203 (29%), Gaps = 9/203 (4%) Query: 66 HGITNEDAVQGVANEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANE 125 HG G E + G +D G E G G E+ G + Sbjct: 574 HGKDGLMGSPGFKGEAGSPGAPGQDGTRG---EPGIPGFPGNRGLMGQKGEIGPPGQQGK 630 Query: 126 DAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKED---AA 182 G+ G + G GI A G+ E A E Sbjct: 631 KGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGL 690 Query: 183 QDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANE 242 I + +G E +QG E+ QGI + QG+ +G E GV Sbjct: 691 PGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQ---QGIQGHHGAKGERGEKGEPGVRGA 747 Query: 243 VEVQGVAHEDAVQGIANEDAAHG 265 + +G + D + G A G Sbjct: 748 IGSKGESGVDGLMGPAGPKGQPG 770 Score = 39.7 bits (91), Expect = 0.036 Identities = 61/348 (17%), Positives = 97/348 (27%), Gaps = 31/348 (8%) Query: 1919 QGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANE 1978 QG + + G G + QGIA G A G+ G + Sbjct: 454 QGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGD 513 Query: 1979 DAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGI 2038 +G+ + G+ G + + A+G G+ G Sbjct: 514 KGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLP------GP 567 Query: 2039 ANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAK 2098 A E HG + P + G +D G E + G Sbjct: 568 AGEPGRHGKDG-----LMGSPGFKGEAGSPGAPGQDGTRG--EPGIPGFPGNRGLMGQKG 620 Query: 2099 QDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQG 2158 + G + A G+ + + G + G G+ A G+ E A G Sbjct: 621 EIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATG 680 Query: 2159 VANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVA 2218 E G + GI + +G E G E+ QG+ + Sbjct: 681 SPGEPGYMG---------------LPGIQGKKGDKGNQGEKGIQGQKGENGRQGIPGQ-- 723 Query: 2219 AQGVANEDAAQGVANEVAVHGVANEDAARHMAKEDAAQGIANEDAAHG 2266 QG+ A+G E GV ++ + D G A G Sbjct: 724 -QGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPG 770 Score = 38.9 bits (89), Expect = 0.061 Identities = 61/297 (20%), Positives = 91/297 (30%), Gaps = 13/297 (4%) Query: 219 QGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANE 278 QG+A V G +G+ G + +G+ HG+ G + Sbjct: 481 QGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGD 540 Query: 279 DAAQGIANEDAAQGIAHEDAVQGI---ANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAA 335 + G + A+G G+ A E HG + + G E + D Sbjct: 541 KGSPGFYGKKGAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGT 600 Query: 336 HGIANEVATQGIATEDVADGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVAN 395 G E G G E G + A G+ G + G + Sbjct: 601 RG---EPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGS 657 Query: 396 EDAAQAIAKPDAAHGIANEVAAHGIANEDAAQG---IANEVAAHGISKEDAVQGIANEDA 452 + P A+ G+ E A G E G I + G E +QG E+ Sbjct: 658 KGEPGIQGMPGAS-GLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGENG 716 Query: 453 AQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARG 509 QGI + QGI +G E GV + + G + D A P G Sbjct: 717 RQGIPGQ---QGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPG 770 Score = 38.5 bits (88), Expect = 0.080 Identities = 56/302 (18%), Positives = 88/302 (29%), Gaps = 17/302 (5%) Query: 228 QGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANE 287 QG+A V G +G+ G + G+ HG+ G + Sbjct: 481 QGIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGD 540 Query: 288 DAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGI 347 + G + +G G+ G A E H + G E + G Sbjct: 541 KGSPGFYGKKGAKGEKGNAGFPGLP------GPAGEPGRHGKDGLMGSPGFKGEAGSPGA 594 Query: 348 ATEDVADGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDA 407 +D G G + G QG + G++ + + P + Sbjct: 595 PGQDGTRGEPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGS 654 Query: 408 AH-----GIANEVAAHGIANEDAAQGIANE---VAAHGISKEDAVQGIANEDAAQGIAHE 459 GI A G+ E A G E + GI + +G E QG E Sbjct: 655 KGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKGE 714 Query: 460 DAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGV---ANKDAAHAIAKPDAARGIANEVAA 516 + QGI + +QG G E G + + P +G + Sbjct: 715 NGRQGIPGQQGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPGDPGP 774 Query: 517 QG 518 QG Sbjct: 775 QG 776 Score = 38.1 bits (87), Expect = 0.10 Identities = 85/454 (18%), Positives = 135/454 (29%), Gaps = 51/454 (11%) Query: 1785 GVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKED 1844 G+A ARG+ G + G+P HG+ G + Sbjct: 482 GIAGTPGVPGSPGIQGARGLPGYKGEPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDK 541 Query: 1845 AVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIA 1904 G + A+G +G A + G A E HG + G Sbjct: 542 GSPGFYGKKGAKG---------------EKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFK 586 Query: 1905 NEDAAQDIANEDAAQGISKEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAH 1964 E + +D +G E + G G E G + A G+ + ++ Sbjct: 587 GEAGSPGAPGQDGTRG---EPGIPGFPGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSN 643 Query: 1965 GIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANED---AAHAIAKPDAARGIA 2021 G + G GI G+ E G E I +G Sbjct: 644 GSPGQPGTPGSKGSKGEPGIQGMPGASGLKGEPGATGSPGEPGYMGLPGIQGKKGDKGNQ 703 Query: 2022 NEVAAQGIATEDVADGIANEDAA---HGVANEDAAQAIAKPDAAHGIANEGIATEDVADG 2078 E QG E+ GI + HG E + +P I ++G E DG Sbjct: 704 GEKGIQGQKGENGRQGIPGQQGIQGHHGAKGERGEK--GEPGVRGAIGSKG---ESGVDG 758 Query: 2079 IAEDA-VQGITNEEAAQAIAKQDAAHG--ITKEDAAQGVTNEVAAQ--------GVANED 2127 + A +G + Q D G +++ Q T+ + AQ + N D Sbjct: 759 LMGPAGPKGQPGDPGPQGPPGLDGKPGREFSEQFIRQVCTDVIRAQLPVLLQSGRIRNCD 818 Query: 2128 ---AAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVANEVEVQGIAHKDAIQ 2184 + HG G + +G+ G+ D V G+ G+ + Sbjct: 819 HCLSQHGSPGIPGPPGPIGPEGPRGL------PGLPGRDGVPGLVGVPGRPGVRGLKGLP 872 Query: 2185 GIANEDAAQGVA--NEVAAHGVANEDAAQGVANE 2216 G E +QG E G + G++ E Sbjct: 873 GRNGEKGSQGFGYPGEQGPPGPPGPEGPPGISKE 906 Score = 37.4 bits (85), Expect = 0.18 Identities = 58/283 (20%), Positives = 82/283 (28%), Gaps = 13/283 (4%) Query: 563 GIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDAVHGVANED 622 GI G E DG + G+ +HG+ G + G + Sbjct: 494 GIQGARGLPGYKGEPGRDG---DKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKK 550 Query: 623 AAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGI 682 A+G G+ G +D L G + A + P G E G Sbjct: 551 GAKGEKGNAGFPGLPGPAGEPGRHGKDGLMGSPGFKGEAGSPGAP-GQDGTRGEPGIPGF 609 Query: 683 ANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAVQGIANEDAV 742 G E G + A G+ G + G GI Sbjct: 610 PGNRGLMGQKGEIGPPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMPGA 669 Query: 743 HGVAKEVAAHGVANEDPVQGVANEDVVQGVANEVEVQGIAHEDAVQGIANEDAAHGIANE 802 G+ E A G E G+ +QG + QG E +QG E+ GI + Sbjct: 670 SGLKGEPGATGSPGEPGYMGLPG---IQGKKGDKGNQG---EKGIQGQKGENGRQGIPGQ 723 Query: 803 VAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGVA 845 G+ A+G E GV G + D G A Sbjct: 724 ---QGIQGHHGAKGERGEKGEPGVRGAIGSKGESGVDGLMGPA 763 Score = 33.5 bits (75), Expect = 2.6 Identities = 65/339 (19%), Positives = 97/339 (28%), Gaps = 23/339 (6%) Query: 227 VQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAN 286 +QG + + G G + QGIA G A G+ G Sbjct: 453 LQGPKGDPGLPGNPGYPGQPGQDGKPGYQGIAGTPGVPGSPGIQGARGLP------GYKG 506 Query: 287 EDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQG 346 E G + + G + G E+ A G + G A G Sbjct: 507 EPGRDGDKGDRGLPGFPGLHGMPGSKGEMGAKGDKGSPGFYGKKGAKGEKGNAGFPGLPG 566 Query: 347 IATEDVADGIANEDAAHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANED--AAQAIAK 404 A E G + G E + G +D +G E + G N + Sbjct: 567 PAGEPGRHGKDGLMGSPGFKGEAGSPGAPGQDGTRG---EPGIPGFPGNRGLMGQKGEIG 623 Query: 405 PDAAHGIANEVAAHGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQG 464 P G G+ + + G + G E +QG+ A G+ E A G Sbjct: 624 PPGQQGKKGAPGMPGLMGSNGSPGQPGTPGSKGSKGEPGIQGMP---GASGLKGEPGATG 680 Query: 465 IAHEDAVQGIANEDAVHGVAKEVAAHGVANKDAAHAIAKPDAARGIANEVAAQGIATEDV 524 E G+ G G+ + + +GI + QGI Sbjct: 681 SPGEPGYMGLPGIQGKKGDKGNQGEKGIQGQKG------ENGRQGIPGQ---QGIQGHHG 731 Query: 525 ADGIANEDAVHGVANEVAAHGVANEDAAHAIAKPDAAHG 563 A G E GV + + G + D A P G Sbjct: 732 AKGERGEKGEPGVRGAIGSKGESGVDGLMGPAGPKGQPG 770 >gi|148536823 type IV alpha 6 collagen isoform A precursor [Homo sapiens] Length = 1691 Score = 53.9 bits (128), Expect = 2e-06 Identities = 236/1432 (16%), Positives = 390/1432 (27%), Gaps = 103/1432 (7%) Query: 202 GIANEDAAQGIAKEDPVQGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANED 261 GI QG + G+ E G+ +G + V G + GI Sbjct: 56 GIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFL---GINGIPGHP 112 Query: 262 AAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANE--DAVHGVAKEVAAHG 319 G G A G D G+ + G D V G Sbjct: 113 GQPGPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKGMKG 172 Query: 320 VANEDAAHAIAKPDAAHGIANEVATQG---IATEDVADGIANEDAAHGVAKEVTAHGVAN 376 I P A G V G + G D G+ G Sbjct: 173 DPGLPGLDGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGL-------GFQG 225 Query: 377 EDAVQGVVNEDALHGVVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEVAAH 436 E V+G V G + + + P G E G G + Sbjct: 226 EKGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGPPGFPG-LGTT 284 Query: 437 GISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANKD 496 G E +GI +G + QG + +G ++G G+ + Sbjct: 285 GEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGF------QGIEGQK 338 Query: 497 AAHAIAKPDAARGIANEVAAQGIATEDVAD--GIANEDAVHGVANEVAAHGVANEDAAHA 554 + PD I V + V G+ ++ + G+ G+ Sbjct: 339 GDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPG 398 Query: 555 IAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVANEVAVHGVAIEDAVQGVANEDA 614 P G+ + G T A G+ D G E + Sbjct: 399 ALGPQGFPGLKGDQGNPGRTTIGAA-GLPGRDGLPGPPGPPGPPSPEFET--------ET 449 Query: 615 VHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKPD--AAHG 672 +H E G+ E G ++G A G V N P G Sbjct: 450 LHN--KESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIG 507 Query: 673 IANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDA 732 + A G AQG A G G E + I +G + Sbjct: 508 LPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQG 567 Query: 733 VQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVANE--------VEVQGIAHE 784 +G+ E GV G+ D QG E + G+ E + G+ Sbjct: 568 FRGVIGEPGKDGVPGLPGLPGLPG-DGGQGFPGEKGLPGLPGEKGHPGPPGLPGNGLPGL 626 Query: 785 DAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVHGVANEDAAQGV 844 +G+ + G+ + G + G G G Sbjct: 627 PGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGT 686 Query: 845 AKEVTAHGVTNEDAVQGVVNEEALHGVVANEDAAQAIAKPDAAHGIANEGVANEVAAQGI 904 + + G E G+V+ L G P +G+ + + G+ Sbjct: 687 PGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLP---GKDGLPGMIGSPGL 743 Query: 905 ATEDVADGIAKDAAHGITKEEAAQAIAKQDAAHSITNEDAAQGVANEDAAHGVANEDAAQ 964 A G A +G E+ Q + + +GV + G E + Sbjct: 744 PGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSP 803 Query: 965 GVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHK------------------D 1006 G +V G +G+ + + G + G K Sbjct: 804 GTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLP 863 Query: 1007 AIQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIA 1066 ++G+ G+ + G+A A G E + G G+ +G+ Sbjct: 864 GLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLK 923 Query: 1067 NEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQ 1126 + G G E +G + + ++ + + QG A + Sbjct: 924 GIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDKGSQGSAGSNGFP 983 Query: 1127 GVANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAH-------GIANEDAAQGIANEDAA 1179 G + +G A G+ GI V+ GI +G + Sbjct: 984 GPRGD---KGEAGRPGPPGLPGAPGLPGIIKGVSGKPGPPGFMGIRGLPGLKGSSGITGF 1040 Query: 1180 QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATE 1239 G+ E QGI + G + G + I+ +G E +G Sbjct: 1041 PGMPGESGSQGIRGSPGLPGASGLPGLKG--DNGQTVEISGSPGPKGQPGESGFKGTKGR 1098 Query: 1240 DVA------DGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANE 1293 D G ED GV+ +V G+ G+A G+ QG Sbjct: 1099 DGLIGNIGFPGNKGEDGKVGVSGDV---GLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGP 1155 Query: 1294 DAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGI 1353 + G+ G + G+ G ++ G+ G E GI Sbjct: 1156 LGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTP-GPSITGVPGPAGLPGPKGEKGYPGI 1214 Query: 1354 A-NEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEVE 1412 + + +G +QG A A GI+ + G + G+ E Sbjct: 1215 GIGAPGKPGLRGQKGDRGF---PGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERG 1271 Query: 1413 VQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIAN 1472 G A G ++ G + GI +G G+ E ++G+ Sbjct: 1272 RPGPAGPPGPPGPSSN---QGDTGDPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRG 1328 Query: 1473 EDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANE----VATQGIATEDVADGIANED 1528 E G +V G A P + G+ + + + G+ D Sbjct: 1329 EPGFMGTPGKVGPPGDPGFPGMKGKAGPRGSSGLQGDPGQTPTAEAVQVPPGPLGLPGID 1388 Query: 1529 AAHGVANEVAAQ---GIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQG 1577 G+ + AQ G+ + G+ +D G+ A G +QG Sbjct: 1389 GIPGLTGDPGAQGPVGLQGSKGLPGIPGKDGPSGLPGPPGALGDPGLPGLQG 1440 Score = 44.3 bits (103), Expect = 0.001 Identities = 184/1160 (15%), Positives = 328/1160 (28%), Gaps = 94/1160 (8%) Query: 1118 GVANEDAVQGVANEVEVQGVAHEDAVQGIAN------EDAAHGIANEVAAHGIANEDAAQ 1171 G+ QG + G+ E G+ + G+ + +GI Sbjct: 56 GIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGHPGQP 115 Query: 1172 GIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEV 1231 G G G D G+ G +A P + +G+ + Sbjct: 116 GPRGPPGLDGCNGTQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLA-PGSFKGMKGDP 174 Query: 1232 AAQGIATEDVADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIA 1291 G+ DGI A G V G G+ G D G+ Sbjct: 175 GLPGL------DGITGPQGAPGFPGAVGPAG------PPGLQGPPGPPGPLGPDGNMGLG 222 Query: 1292 NEDAAQGIAKEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQ 1351 + +G+ + + G A P G E++ + +G E G Sbjct: 223 FQ-GEKGVKGDVGLPGPAGPPPSTG-----ELEFMGFPKGKKGSKGEPGPKGFPGISGPP 276 Query: 1352 GIANEDAAQDIANEDAAQGISKEDAVQGIANEDAAQGIAKEDPVQGVANEDAVQGVANEV 1411 G + E +GI +G + QG + +G + G Sbjct: 277 GFPGLGTTGE-KGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGF---- 331 Query: 1412 EVQGVAHEDAVQGIANEDAAHGIANEVAAH--GIANEDAAQGIANEDAAQGIAHEDAVQG 1469 QG+ + G+ D I V + G G+ ++ QG+ V G Sbjct: 332 --QGIEGQKGDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPG 389 Query: 1470 IANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAR-----GIANEVATQGIATEDV-ADG 1523 + V G G+ + AA G+ G + + + Sbjct: 390 LPALSGVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETET 449 Query: 1524 IANEDAAH-GVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGVVNED 1582 + N+++ G+ E +G + G + A G V G G++ Sbjct: 450 LHNKESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLP 509 Query: 1583 ALHSVVANEDAAQAIAKPDAAHGIANEVAAHSIANKDAAQGIANQDAAQGIANEVAAHGI 1642 L + + A P A G+ + K +G QG+ + G Sbjct: 510 GLKGARGDRGSGGAQG-PAGAPGLVGPLGPSGPKGK---KGEPILSTIQGMPGD---RGD 562 Query: 1643 SKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPV 1702 S +G+ E G+ G+ D QG E + G+ E G P Sbjct: 563 SGSQGFRGVIGEPGKDGVPGLPGLPGLPG-DGGQGFPGEKGLPGLPGEKGHPGPPGL-PG 620 Query: 1703 QGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIAHE 1762 G+ +G+ + G+ + + G I G G Sbjct: 621 NGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGS 680 Query: 1763 DAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGI 1822 + G + E + G+ + P +G+ G G Sbjct: 681 RGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIGS 740 Query: 1823 PNEDAAHGVANEV--AAHGISKEDAVQGIANEDAAQGIAKEDPIQGVANEVEVQGVAHED 1880 P + G ++ A +G E +QG+ G + ++GV + + G E Sbjct: 741 PGLPGSKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGER 800 Query: 1881 AVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIANQDAAQG-I 1939 G + G GI + + GIS +G + G I Sbjct: 801 GSPGTPGQVGQPGTPGSSGPYGIKGKSG---LPGAPGFPGISGHPGKKGTRGKKGPPGSI 857 Query: 1940 AKED--AVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANED 1997 K+ ++G+ G+ + G+A A G E + G + G+ Sbjct: 858 VKKGLPGLKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIPGLPGIP 917 Query: 1998 AVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEDAAQAIA 2057 G+ + P G E +G + Sbjct: 918 GTRGLKGIPGSTGKMGPSGRAGTPGEKGDRG-----------------------NPGPVG 954 Query: 2058 KPDAAHGIANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHGITKEDAAQGVTNE 2117 P ++N + + + G A G + A + G+ G+ Sbjct: 955 IPSPRRPMSNLWLKGDKGSQGSAGS--NGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKG 1012 Query: 2118 VAAQ-------GVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDAVQGVAN 2170 V+ + G+ G + G+ E +QG+ G + ++G Sbjct: 1013 VSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNG 1072 Query: 2171 E-VEVQGIAH---KDAIQGIANEDAAQGVANEVAAHGVANEDAAQGVANEVAAQGVANED 2226 + VE+ G + G G+ + G ED GV+ +V G Sbjct: 1073 QTVEISGSPGPKGQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFP 1132 Query: 2227 AAQGVANEVAVHGVANEDAA 2246 G+ E + G + A Sbjct: 1133 GVAGMRGEPGLPGSSGHQGA 1152 Score = 37.7 bits (86), Expect = 0.14 Identities = 205/1275 (16%), Positives = 357/1275 (28%), Gaps = 106/1275 (8%) Query: 1010 GIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKEDAVQGIANED 1069 GI G G+ E G+ +G + G + + G + Sbjct: 56 GIQGPTGPQGFTGSTGLSGLKGERGFPGLLGPYGPKGDKGPMGVPGFLGINGIPGHPGQP 115 Query: 1070 AAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQG--VANEDAVQG 1127 +G D G QG G + G+ + +G V + +G Sbjct: 116 GPRGPPGLDGCNG------TQGAVGFPGPDGYPGLLGPPGLPGQKGSKGDPVLAPGSFKG 169 Query: 1128 VANEVEVQGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDA 1187 + + + G+ D + G G G+ G D G+ + Sbjct: 170 MKGDPGLPGL---DGITGPQGAPGFPGAVGPAGPPGLQGPPGPPGPLGPDGNMGLGFQGE 226 Query: 1188 VQGIANEDAVHGVAKEVAAHGVAN-------EDAAHAIAKPDAARGIANEVAAQGIATED 1240 +G+ + + G A + G + + P GI+ G+ T Sbjct: 227 -KGVKGDVGLPGPAGPPPSTGELEFMGFPKGKKGSKGEPGPKGFPGISGPPGFPGLGTT- 284 Query: 1241 VADGIANEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIA 1300 G E G+ G + VQG + +G + G QGI Sbjct: 285 ---GEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQQGKKGTLGFPGLNGF------QGIE 335 Query: 1301 KEDPVQGVANEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQ 1360 + G+ D + V + G + V G+ GI G+ A Sbjct: 336 GQKGDIGLPGPDVFIDIDGAV-ISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALS 394 Query: 1361 DIANEDAAQGISKEDAVQGIANEDA--AQGIAKEDPVQGVANEDAVQGVANEVEV----- 1413 + QG QG A G+ D + G E E Sbjct: 395 GVPGALGPQGFPGLKGDQGNPGRTTIGAAGLPGRDGLPGPPGPPGPPSPEFETETLHNKE 454 Query: 1414 ---------QGVAHEDAVQGIANEDAAHGIANEVAAHGIANEDAAQG------IANEDAA 1458 QG ++GI + V G E G + A Sbjct: 455 SGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIGLPGLKGA 514 Query: 1459 QGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAARGIANEVATQGIATE 1518 +G QG A + G G E I RG + +G+ E Sbjct: 515 RGDRGSGGAQGPAGAPGLVGPLGPSGPKGKKGEPILSTIQGMPGDRGDSGSQGFRGVIGE 574 Query: 1519 DVADGIANEDAAHGVANEVAAQGIANEVAVHGVAIEDAVQGVVKEVTAHGVANEDAVQGV 1578 DG+ G+ + QG E + G+ E G + +G+ +G+ Sbjct: 575 PGKDGVPGLPGLPGLPGD-GGQGFPGEKGLPGLPGEKGHPGP-PGLPGNGLPGLPGPRGL 632 Query: 1579 VNEDALHSVVANED--AAQAIAKP---DAAHGIANEVAAHSIANKDAAQGIAN---QDAA 1630 + + + ++ I P ++G + ++G+ Q + Sbjct: 633 PGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKGSRGLPGTPGQPGS 692 Query: 1631 QGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKE 1690 G E + G+ + G +G+ G+ +D + G+ + G Sbjct: 693 SGSKGEPGSPGLVHLPELPGFPGPRGEKGLPG---FPGLPGKDGLPGMIGSPGLPGSKGA 749 Query: 1691 V-----AAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQGIANEDAAHGITNEV 1745 A +G E +QG+ G + ++GV + + G E + G +V Sbjct: 750 TGDIFGAENGAPGEQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGPKGERGSPGTPGQV 809 Query: 1746 AAHGIANEDAAQGIAHEDAVQGIANEDAVHSVAKEVAAHGVANEDAAHAIAKPDAARGIA 1805 G GI + + G + + G +G Sbjct: 810 GQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRG---------------KKGPP 854 Query: 1806 NEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQGIANEDAAQGIAKEDPIQ 1865 + +G+ G+P G+ + G++ A+ G E + G I Sbjct: 855 GSIVKKGLPG---LKGLPGNPGLVGLKGSPGSPGVAGLPALSGPKGEKGSVGFVGFPGIP 911 Query: 1866 GVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKED 1925 G+ +G+ G G E +G + + + Sbjct: 912 GLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLWLKGDK 971 Query: 1926 AVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGIANEDAAQGIANEDAAQGIA 1985 QG A + G + +G A G+ GI G GI Sbjct: 972 GSQGSAGSNGFPGPRGD---KGEAGRPGPPGLPGAPGLPGIIK--GVSGKPGPPGFMGIR 1026 Query: 1986 HEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAH 2045 ++G + G+ E + I G + +G + V I+ Sbjct: 1027 GLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVE--ISGSPGPK 1084 Query: 2046 GVANEDAAQAIAKPDAAHG-IANEGIATEDVADGIAEDAVQGITNEEAAQAIAKQDAAHG 2104 G E + D G I G ED G++ D G+ +A G Sbjct: 1085 GQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDV--GLPGAPGFPGVAGMRGEPG 1142 Query: 2105 ITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDAAQGVANEVAAQGVANEDA 2164 + QG + + G+ G +G+ G + GV Sbjct: 1143 LPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHGLNGLPGTKGTHGTPGP-SITGVPGPAG 1201 Query: 2165 VQGVANEVEVQGIA----HKDAIQGIANE---DAAQGVANEVAAHGVANEDAAQGVANEV 2217 + G E GI K ++G + QG A A G++ G + Sbjct: 1202 LPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFPGLQGPAGLPGAPGISLPSLIAGQPGDP 1261 Query: 2218 AAQGVANEDAAQGVA 2232 G+ E G A Sbjct: 1262 GRPGLDGERGRPGPA 1276 Score = 37.0 bits (84), Expect = 0.23 Identities = 198/1221 (16%), Positives = 328/1221 (26%), Gaps = 83/1221 (6%) Query: 965 GVANEVAAQGVANEDAVHGVANEDAVQGVANEVEVQGIAHKDAIQGIANEDAAHGIANEV 1024 G E +G+ G + VQG + QG K G + GI + Sbjct: 285 GEKGEKGEKGIPGLPGPRGPMGSEGVQGPPGQ---QG---KKGTLGFPGLNGFQGIEGQK 338 Query: 1025 AAHGIANEDAAQGI--ANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQG 1082 G+ D I A G G+ ++ +QG+ G+ G Sbjct: 339 GDIGLPGPDVFIDIDGAVISGNPGDPGVPGLPGLKGDEGIQGLRGPSGVPGLPALSGVPG 398 Query: 1083 IAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDA 1142 G+ + G + A G+ D + G E E H Sbjct: 399 ALGPQGFPGLKGDQGNPG-RTTIGAAGLPGRDGLPGPPGPPGPPSPEFETET---LHN-- 452 Query: 1143 VQGIANEDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVAK 1202 E G+ E G +G + A G G G+ Sbjct: 453 -----KESGFPGLRGEQGPKGNLGLKGIKGDSGFCACDGGVPNTGPPGEPGPPGPWGLIG 507 Query: 1203 EVAAHGVANEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDAAHGVANEVAAHG 1262 G + + P A G+ + G G E + G Sbjct: 508 LPGLKGARGDRGSGGAQGPAGAPGLVGPLGPSG------PKGKKGEPILSTIQGMPGDRG 561 Query: 1263 ISKEDAVQGIANEDAAQGIAKEDAVQGIANEDAAQGIAKEDPVQGVANEDPIQGVANEVE 1322 S +G+ E G+ + G+ D QG E + G+ E G + Sbjct: 562 DSGSQGFRGVIGEPGKDGVPGLPGLPGLPG-DGGQGFPGEKGLPGLPGEKGHPGPPG-LP 619 Query: 1323 VQGVAHEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIANEDAAQGISKEDAVQGIAN 1382 G+ +G+ + G+ + G I G G Sbjct: 620 GNGLPGLPGPRGLPGDKGKDGLPGQQGLPGSKGITLPCIIPGSYGPSGFPGTPGFPGPKG 679 Query: 1383 EDAAQGIAKEDPVQGVANEDAVQGVANEVEVQGVAH---EDAVQGIANEDAAHGIANEVA 1439 G + G E G+ + E+ G E + G G+ + Sbjct: 680 SRGLPGTPGQPGSSGSKGEPGSPGLVHLPELPGFPGPRGEKGLPGFPGLPGKDGLPGMIG 739 Query: 1440 AHGIANEDAAQG--IANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDAAHAI 1497 + G+ A G E+ A G E +QG+ G + GV + Sbjct: 740 SPGLPGSKGATGDIFGAENGAPG---EQGLQGLTGHKGFLGDSGLPGLKGVHGKPGLLGP 796 Query: 1498 AKPDAARGIANEVATQGIATEDVADGIANEDAAHG------VANEVAAQGIANEVAVHGV 1551 + G +V G GI + G ++ +G + G Sbjct: 797 KGERGSPGTPGQVGQPGTPGSSGPYGIKGKSGLPGAPGFPGISGHPGKKGTRGKKGPPGS 856 Query: 1552 AIEDAVQGVVKEVTAHGVANEDAVQGVVNEDALHSVVANEDAAQAIAKPDAAHGIANEVA 1611 ++ + G+ G+ + G+ V A++ P G V Sbjct: 857 IVKKGLPGL------KGLPGNPGLVGLKGSPGSPGVAG----LPALSGPKGEKGSVGFVG 906 Query: 1612 AHSIANKDAAQGIANQDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIANEDAAQGIAH 1671 I G G ++ G + +G GI + Sbjct: 907 FPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRGNPGPVGIPSPRRPMSNLW 966 Query: 1672 EDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDAVQGVANEVEVQGVAHEDAVQG 1731 +G +G G A G+ + G+ V G G Sbjct: 967 LKGDKGSQGSAGSNGFPGPRGDKGEAGRPGPPGLPGAPGLPGIIKGVS--GKPGPPGFMG 1024 Query: 1732 IANEDAAHGITNEVAAHGIANEDAAQGIAHEDAVQGIANEDAVHS----VAKEVAAHGVA 1787 I G + G+ E +QGI + G + + + + G Sbjct: 1025 IRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPGASGLPGLKGDNGQTVEISGSPGPK 1084 Query: 1788 NEDAAHAIAKPDAARGIANEVAAQGIATEDVADGIPNEDAAHGVANEVAAHGISKEDAVQ 1847 + G+ + G ED G+ + G G+ E + Sbjct: 1085 GQPGESGFKGTKGRDGLIGNIGFPGNKGEDGKVGVSGDVGLPGAPGFPGVAGMRGEPGLP 1144 Query: 1848 GIANEDAAQGIAKEDPIQGVANEVEVQGVAHEDAVQGIANEDAAHGIANEDAAQGIANED 1907 G + A G + G G+ + G+ HG G+ Sbjct: 1145 GSSGHQGAIGPLGSPGLIGPKGFPGFPGL---HGLNGLPGTKGTHGTPGPSIT-GVPGPA 1200 Query: 1908 AAQDIANEDAAQGIS-KEDAVQGIANQDAAQGIAKEDAVQGIANEDAAQGIANEVAAHGI 1966 E GI G+ Q +G +QG A A GI+ G Sbjct: 1201 GLPGPKGEKGYPGIGIGAPGKPGLRGQKGDRGFP---GLQGPAGLPGAPGISLPSLIAGQ 1257 Query: 1967 ANEDAAQGIANEDAAQGIAHEDAVQGIANEDAVHGVANEDAAHAIAKPDAARGIANEVAA 2026 + G+ E G A G ++ G + I P +G Sbjct: 1258 PGDPGRPGLDGERGRPGPAGPPGPPGPSSNQ---GDTGDPGFPGIPGPKGPKGDQGIPGF 1314 Query: 2027 QGIATEDVADGIANEDAAHGVANEDAAQAIAKPDAAHGIANEGIATEDVADGIAEDAVQG 2086 G+ E G+ E G + + P +G A + G+ D Q Sbjct: 1315 SGLPGELGLKGMRGEPGFMGTPGK-----VGPPGDPGFPGMKGKAGPRGSSGLQGDPGQT 1369 Query: 2087 ITNEEAAQAIAKQDAAHGITKEDAAQGVTNEVAAQGVANEDAAHGVANEVAAHGVANEDA 2146 T A+A+ G+ D G+T + AQG + G+ G+ +D Sbjct: 1370 PT----AEAVQVPPGPLGLPGIDGIPGLTGDPGAQGPVGLQGSKGLP------GIPGKDG 1419 Query: 2147 AQGVANEVAAQGVANEDAVQG 2167 G+ A G +QG Sbjct: 1420 PSGLPGPPGALGDPGLPGLQG 1440 Score = 36.2 bits (82), Expect = 0.39 Identities = 129/790 (16%), Positives = 223/790 (28%), Gaps = 62/790 (7%) Query: 67 GITNEDAVQGVANEVAAQGVANEDAAHGVANEV--AAHGVANEDAAQGVANEVAAQGVAN 124 G+ +D + G+ G + G ++ A +G E QG+ G + Sbjct: 727 GLPGKDGLPGMIGSPGLPG------SKGATGDIFGAENGAPGEQGLQGLTGHKGFLGDSG 780 Query: 125 EDAVQGVANEDAVQGVANEDAVQGIANEDAAHGIANEDAAQGIANEDAAQDIAKEDAAQD 184 ++GV + + G E G + G GI + Sbjct: 781 LPGLKGVHGKPGLLGPKGERGSPGTPGQVGQPGTPGSSGPYGIKGKSG------------ 828 Query: 185 IANEDAAQGISKEDAVQGIANEDAAQG--IAKEDP-VQGVANEDPVQGVANEDAVQGVAN 241 + GIS +G + G + K P ++G+ + G+ GVA Sbjct: 829 LPGAPGFPGISGHPGKKGTRGKKGPPGSIVKKGLPGLKGLPGNPGLVGLKGSPGSPGVAG 888 Query: 242 EVEVQGVAHEDAVQGIANEDAAHGITNEVAAHGIANEDAAQGIANEDAAQGIAHEDAVQG 301 + G E G G+ G+ + G G E +G Sbjct: 889 LPALSGPKGEKGSVGFVGFPGIPGLPGIPGTRGLKGIPGSTGKMGPSGRAGTPGEKGDRG 948 Query: 302 IANEDAVHGVAKEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDA 361 + + ++ + + + A ++G +G A G+ Sbjct: 949 NPGPVGIPSPRRPMSNLWLKGDKGSQGSA---GSNGFPGPRGDKGEAGRPGPPGLPGAPG 1005 Query: 362 AHGVAKEVTAHGVANEDAVQGVVNEDALHGVVANEDAAQAIAKP--DAAHGIANEVAAHG 419 G+ K GV+ + G + L G+ + P + GI G Sbjct: 1006 LPGIIK-----GVSGKPGPPGFMGIRGLPGLKGSSGITGFPGMPGESGSQGIRGSPGLPG 1060 Query: 420 IANEDAAQGIANEVAAHGISKEDAVQGIANEDAAQGIAHEDAAQGIAHEDAVQGIANEDA 479 + +G + IS +G E +G D G+ G ED Sbjct: 1061 ASGLPGLKGDNGQTVE--ISGSPGPKGQPGESGFKGTKGRD---GLIGNIGFPGNKGEDG 1115 Query: 480 VHGVAKEVAA------HGVANKDAAHAIAKPDAARGIANEVAAQGIATEDVADGIANEDA 533 GV+ +V GVA + +G + + G+ G Sbjct: 1116 KVGVSGDVGLPGAPGFPGVAGMRGEPGLPGSSGHQGAIGPLGSPGLIGPKGFPGFPGLHG 1175 Query: 534 VHGVANEVAAHGVANEDAAHAIAKPDAAHGIANEVATQGIATEDVADGIANEDAAHGVAN 593 ++G+ HG + P G E GI A G G Sbjct: 1176 LNGLPGTKGTHGTPGPSIT-GVPGPAGLPGPKGEKGYPGIGIG--APGKPGLRGQKGDRG 1232 Query: 594 EVAVHGVAIEDAVQGVANEDAVHGVANEDAAQGIAKEVTAHGVANEDAVQGVVNEDALHG 653 + G A G++ + G + G+ E G A G + G Sbjct: 1233 FPGLQGPAGLPGAPGISLPSLIAGQPGDPGRPGLDGERGRPGPAGPPGPPGPSSNQGDTG 1292 Query: 654 VVANEDAAQAIAKPDAAHGIANEVAAHGIANEDAAQGIANEDAAQGIANEVAAHGISKED 713 + I P G G+ E +G+ E G +V G Sbjct: 1293 ----DPGFPGIPGPKGPKGDQGIPGFSGLPGELGLKGMRGEPGFMGTPGKVGPPGDPGFP 1348 Query: 714 AVQGIANEDAAQGIAHEDAVQGIANEDAVHGVAKEVAAHGVANEDPVQGVANEDVVQGVA 773 ++G A + G+ + V G+ D + G+ + QG Sbjct: 1349 GMKGKAGPRGSSGLQGDP-----GQTPTAEAVQVPPGPLGLPGIDGIPGLTGDPGAQGPV 1403 Query: 774 NEVEVQGIAHEDAVQGIANEDAAHGIANEVAAHGVANEDAAQGVANEDAAQGVANEDAVH 833 G+ + GI +D G+ A G QG + A G + Sbjct: 1404 ------GLQGSKGLPGIPGKDGPSGLPGPPGALGDPGLPGLQGPPGFEGAPGQQGPFGMP 1457 Query: 834 GVANEDAAQG 843 G+ + G Sbjct: 1458 GMPGQSMRVG 1467 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.305 0.122 0.325 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 71,364,975 Number of Sequences: 37866 Number of extensions: 2848421 Number of successful extensions: 23601 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 48 Number of HSP's successfully gapped in prelim test: 79 Number of HSP's that attempted gapping in prelim test: 5861 Number of HSP's gapped (non-prelim): 3069 length of query: 2378 length of database: 18,247,518 effective HSP length: 119 effective length of query: 2259 effective length of database: 13,741,464 effective search space: 31041967176 effective search space used: 31041967176 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 43 (22.0 bits) S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.