Guide to the Human Genome
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Search of human proteins with 239757043

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239757043 PREDICTED: functional smad suppressing element 18
[Homo sapiens]
         (996 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239757043 PREDICTED: functional smad suppressing element 18 [...  2086   0.0  
gi|239751555 PREDICTED: functional smad suppressing element 18 [...  2035   0.0  
gi|239746067 PREDICTED: functional smad suppressing element 18 [...  2035   0.0  
gi|73476377 LBXCOR1 homolog [Homo sapiens]                            458   e-128
gi|4506967 v-ski sarcoma viral oncogene homolog [Homo sapiens]        132   2e-30
gi|223029422 SKI-like isoform 3 [Homo sapiens]                        121   3e-27
gi|223029420 SKI-like isoform 2 [Homo sapiens]                        121   3e-27
gi|223029418 SKI-like isoform 1 [Homo sapiens]                        121   3e-27
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]     99   3e-20
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]     99   3e-20
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    93   1e-18
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    93   1e-18
gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens]    86   1e-16
gi|40288197 GATA binding protein 6 [Homo sapiens]                      86   2e-16
gi|148762982 hypothetical protein LOC387640 [Homo sapiens]             85   4e-16
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      83   1e-15
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    81   4e-15
gi|5453936 POU class 3 homeobox 3 [Homo sapiens]                       80   1e-14
gi|61966923 forkhead box B2 [Homo sapiens]                             79   2e-14
gi|32307177 forkhead box G1 [Homo sapiens]                             79   2e-14
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ...    77   1e-13
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ...    77   1e-13
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ...    76   1e-13
gi|48762934 alpha 2 type I collagen [Homo sapiens]                     76   2e-13
gi|122937424 one cut homeobox 3 [Homo sapiens]                         74   5e-13
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    74   7e-13
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    74   9e-13
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    73   2e-12
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    73   2e-12
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      70   1e-11

>gi|239757043 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 996

 Score = 2086 bits (5404), Expect = 0.0
 Identities = 996/996 (100%), Positives = 996/996 (100%)

Query: 1   MASSPLPGPNDILLASPSSAFQPDTLSQPRPGHANLKPNQVGQVILYGIPIVSLVIDGQE 60
           MASSPLPGPNDILLASPSSAFQPDTLSQPRPGHANLKPNQVGQVILYGIPIVSLVIDGQE
Sbjct: 1   MASSPLPGPNDILLASPSSAFQPDTLSQPRPGHANLKPNQVGQVILYGIPIVSLVIDGQE 60

Query: 61  RLCLAQISNTLLKNFSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITK 120
           RLCLAQISNTLLKNFSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITK
Sbjct: 61  RLCLAQISNTLLKNFSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITK 120

Query: 121 REAERLCKSFLGENRPPKLPDNFAFDVSHECAWGCRGSFIPARYNSSRAKCIKCSYCNMY 180
           REAERLCKSFLGENRPPKLPDNFAFDVSHECAWGCRGSFIPARYNSSRAKCIKCSYCNMY
Sbjct: 121 REAERLCKSFLGENRPPKLPDNFAFDVSHECAWGCRGSFIPARYNSSRAKCIKCSYCNMY 180

Query: 181 FSPNKFIFHSHRTPDAKYTQPDAANFNSWRRHLKLTDKSPQDELVFAWEDVKAMFNGGSR 240
           FSPNKFIFHSHRTPDAKYTQPDAANFNSWRRHLKLTDKSPQDELVFAWEDVKAMFNGGSR
Sbjct: 181 FSPNKFIFHSHRTPDAKYTQPDAANFNSWRRHLKLTDKSPQDELVFAWEDVKAMFNGGSR 240

Query: 241 KRALPQPGAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPPPLAELAG 300
           KRALPQPGAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPPPLAELAG
Sbjct: 241 KRALPQPGAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPPPLAELAG 300

Query: 301 APHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGV 360
           APHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGV
Sbjct: 301 APHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGV 360

Query: 361 GVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSL 420
           GVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSL
Sbjct: 361 GVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSL 420

Query: 421 CHKKEDAGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLP 480
           CHKKEDAGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLP
Sbjct: 421 CHKKEDAGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLP 480

Query: 481 VPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGP 540
           VPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGP
Sbjct: 481 VPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGP 540

Query: 541 GSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVP 600
           GSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVP
Sbjct: 541 GSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVP 600

Query: 601 APHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTHPHHHHHP 660
           APHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTHPHHHHHP
Sbjct: 601 APHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTHPHHHHHP 660

Query: 661 HHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQHPHHRGLLSPG 720
           HHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQHPHHRGLLSPG
Sbjct: 661 HHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQHPHHRGLLSPG 720

Query: 721 GTSCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPDDDEEEDEETEVLLGDP 780
           GTSCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPDDDEEEDEETEVLLGDP
Sbjct: 721 GTSCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPDDDEEEDEETEVLLGDP 780

Query: 781 LVGGGRFLQGRGPSEKGSSRDRAPAVAGAFPLGLNSSRLLQEDGKLGDPGSDLPPPPPPP 840
           LVGGGRFLQGRGPSEKGSSRDRAPAVAGAFPLGLNSSRLLQEDGKLGDPGSDLPPPPPPP
Sbjct: 781 LVGGGRFLQGRGPSEKGSSRDRAPAVAGAFPLGLNSSRLLQEDGKLGDPGSDLPPPPPPP 840

Query: 841 LAPQKASGGGSSSPGSPVHHPSLEEQPSYKDSQKTKENNQVIVSTKDDNSFSDKNKEHSF 900
           LAPQKASGGGSSSPGSPVHHPSLEEQPSYKDSQKTKENNQVIVSTKDDNSFSDKNKEHSF
Sbjct: 841 LAPQKASGGGSSSPGSPVHHPSLEEQPSYKDSQKTKENNQVIVSTKDDNSFSDKNKEHSF 900

Query: 901 FITDSDASGGDFWRERSGEHTQETNSPHSLKKDVENMGKEELQKVLFEQIDLRRRLEQEF 960
           FITDSDASGGDFWRERSGEHTQETNSPHSLKKDVENMGKEELQKVLFEQIDLRRRLEQEF
Sbjct: 901 FITDSDASGGDFWRERSGEHTQETNSPHSLKKDVENMGKEELQKVLFEQIDLRRRLEQEF 960

Query: 961 QVLKGNTSFPVFKITKLKLAIPVPDDSCISIWKIFK 996
           QVLKGNTSFPVFKITKLKLAIPVPDDSCISIWKIFK
Sbjct: 961 QVLKGNTSFPVFKITKLKLAIPVPDDSCISIWKIFK 996


>gi|239751555 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 1252

 Score = 2035 bits (5273), Expect = 0.0
 Identities = 971/972 (99%), Positives = 971/972 (99%)

Query: 1   MASSPLPGPNDILLASPSSAFQPDTLSQPRPGHANLKPNQVGQVILYGIPIVSLVIDGQE 60
           MASSPLPGPNDILLASPSSAFQPDTLSQPRPGHANLKPNQVGQVILYGIPIVSLVIDGQE
Sbjct: 1   MASSPLPGPNDILLASPSSAFQPDTLSQPRPGHANLKPNQVGQVILYGIPIVSLVIDGQE 60

Query: 61  RLCLAQISNTLLKNFSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITK 120
           RLCLAQISNTLLKNFSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITK
Sbjct: 61  RLCLAQISNTLLKNFSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITK 120

Query: 121 REAERLCKSFLGENRPPKLPDNFAFDVSHECAWGCRGSFIPARYNSSRAKCIKCSYCNMY 180
           REAERLCKSFLGENRPPKLPDNFAFDVSHECAWGCRGSFIPARYNSSRAKCIKCSYCNMY
Sbjct: 121 REAERLCKSFLGENRPPKLPDNFAFDVSHECAWGCRGSFIPARYNSSRAKCIKCSYCNMY 180

Query: 181 FSPNKFIFHSHRTPDAKYTQPDAANFNSWRRHLKLTDKSPQDELVFAWEDVKAMFNGGSR 240
           FSPNKFIFHSHRTPDAKYTQPDAANFNSWRRHLKLTDKSPQDELVFAWEDVKAMFNGGSR
Sbjct: 181 FSPNKFIFHSHRTPDAKYTQPDAANFNSWRRHLKLTDKSPQDELVFAWEDVKAMFNGGSR 240

Query: 241 KRALPQPGAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPPPLAELAG 300
           KRALPQPGAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPPPLAELAG
Sbjct: 241 KRALPQPGAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPPPLAELAG 300

Query: 301 APHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGV 360
           APHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGV
Sbjct: 301 APHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGV 360

Query: 361 GVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSL 420
           GVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSL
Sbjct: 361 GVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSL 420

Query: 421 CHKKEDAGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLP 480
           CHKKEDAGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLP
Sbjct: 421 CHKKEDAGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLP 480

Query: 481 VPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGP 540
           VPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGP
Sbjct: 481 VPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGP 540

Query: 541 GSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVP 600
           GSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVP
Sbjct: 541 GSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVP 600

Query: 601 APHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTHPHHHHHP 660
           APHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTHPHHHHHP
Sbjct: 601 APHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTHPHHHHHP 660

Query: 661 HHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQHPHHRGLLSPG 720
           HHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQHPHHRGLLSPG
Sbjct: 661 HHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQHPHHRGLLSPG 720

Query: 721 GTSCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPDDDEEEDEETEVLLGDP 780
           GTSC YPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPDDDEEEDEETEVLLGDP
Sbjct: 721 GTSCCYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPDDDEEEDEETEVLLGDP 780

Query: 781 LVGGGRFLQGRGPSEKGSSRDRAPAVAGAFPLGLNSSRLLQEDGKLGDPGSDLPPPPPPP 840
           LVGGGRFLQGRGPSEKGSSRDRAPAVAGAFPLGLNSSRLLQEDGKLGDPGSDLPPPPPPP
Sbjct: 781 LVGGGRFLQGRGPSEKGSSRDRAPAVAGAFPLGLNSSRLLQEDGKLGDPGSDLPPPPPPP 840

Query: 841 LAPQKASGGGSSSPGSPVHHPSLEEQPSYKDSQKTKENNQVIVSTKDDNSFSDKNKEHSF 900
           LAPQKASGGGSSSPGSPVHHPSLEEQPSYKDSQKTKENNQVIVSTKDDNSFSDKNKEHSF
Sbjct: 841 LAPQKASGGGSSSPGSPVHHPSLEEQPSYKDSQKTKENNQVIVSTKDDNSFSDKNKEHSF 900

Query: 901 FITDSDASGGDFWRERSGEHTQETNSPHSLKKDVENMGKEELQKVLFEQIDLRRRLEQEF 960
           FITDSDASGGDFWRERSGEHTQETNSPHSLKKDVENMGKEELQKVLFEQIDLRRRLEQEF
Sbjct: 901 FITDSDASGGDFWRERSGEHTQETNSPHSLKKDVENMGKEELQKVLFEQIDLRRRLEQEF 960

Query: 961 QVLKGNTSFPVF 972
           QVLKGNTSFPVF
Sbjct: 961 QVLKGNTSFPVF 972


>gi|239746067 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 1252

 Score = 2035 bits (5273), Expect = 0.0
 Identities = 971/972 (99%), Positives = 971/972 (99%)

Query: 1   MASSPLPGPNDILLASPSSAFQPDTLSQPRPGHANLKPNQVGQVILYGIPIVSLVIDGQE 60
           MASSPLPGPNDILLASPSSAFQPDTLSQPRPGHANLKPNQVGQVILYGIPIVSLVIDGQE
Sbjct: 1   MASSPLPGPNDILLASPSSAFQPDTLSQPRPGHANLKPNQVGQVILYGIPIVSLVIDGQE 60

Query: 61  RLCLAQISNTLLKNFSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITK 120
           RLCLAQISNTLLKNFSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITK
Sbjct: 61  RLCLAQISNTLLKNFSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITK 120

Query: 121 REAERLCKSFLGENRPPKLPDNFAFDVSHECAWGCRGSFIPARYNSSRAKCIKCSYCNMY 180
           REAERLCKSFLGENRPPKLPDNFAFDVSHECAWGCRGSFIPARYNSSRAKCIKCSYCNMY
Sbjct: 121 REAERLCKSFLGENRPPKLPDNFAFDVSHECAWGCRGSFIPARYNSSRAKCIKCSYCNMY 180

Query: 181 FSPNKFIFHSHRTPDAKYTQPDAANFNSWRRHLKLTDKSPQDELVFAWEDVKAMFNGGSR 240
           FSPNKFIFHSHRTPDAKYTQPDAANFNSWRRHLKLTDKSPQDELVFAWEDVKAMFNGGSR
Sbjct: 181 FSPNKFIFHSHRTPDAKYTQPDAANFNSWRRHLKLTDKSPQDELVFAWEDVKAMFNGGSR 240

Query: 241 KRALPQPGAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPPPLAELAG 300
           KRALPQPGAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPPPLAELAG
Sbjct: 241 KRALPQPGAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPPPLAELAG 300

Query: 301 APHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGV 360
           APHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGV
Sbjct: 301 APHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGV 360

Query: 361 GVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSL 420
           GVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSL
Sbjct: 361 GVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSL 420

Query: 421 CHKKEDAGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLP 480
           CHKKEDAGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLP
Sbjct: 421 CHKKEDAGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLP 480

Query: 481 VPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGP 540
           VPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGP
Sbjct: 481 VPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGP 540

Query: 541 GSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVP 600
           GSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVP
Sbjct: 541 GSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVP 600

Query: 601 APHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTHPHHHHHP 660
           APHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTHPHHHHHP
Sbjct: 601 APHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTHPHHHHHP 660

Query: 661 HHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQHPHHRGLLSPG 720
           HHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQHPHHRGLLSPG
Sbjct: 661 HHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQHPHHRGLLSPG 720

Query: 721 GTSCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPDDDEEEDEETEVLLGDP 780
           GTSC YPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPDDDEEEDEETEVLLGDP
Sbjct: 721 GTSCCYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPDDDEEEDEETEVLLGDP 780

Query: 781 LVGGGRFLQGRGPSEKGSSRDRAPAVAGAFPLGLNSSRLLQEDGKLGDPGSDLPPPPPPP 840
           LVGGGRFLQGRGPSEKGSSRDRAPAVAGAFPLGLNSSRLLQEDGKLGDPGSDLPPPPPPP
Sbjct: 781 LVGGGRFLQGRGPSEKGSSRDRAPAVAGAFPLGLNSSRLLQEDGKLGDPGSDLPPPPPPP 840

Query: 841 LAPQKASGGGSSSPGSPVHHPSLEEQPSYKDSQKTKENNQVIVSTKDDNSFSDKNKEHSF 900
           LAPQKASGGGSSSPGSPVHHPSLEEQPSYKDSQKTKENNQVIVSTKDDNSFSDKNKEHSF
Sbjct: 841 LAPQKASGGGSSSPGSPVHHPSLEEQPSYKDSQKTKENNQVIVSTKDDNSFSDKNKEHSF 900

Query: 901 FITDSDASGGDFWRERSGEHTQETNSPHSLKKDVENMGKEELQKVLFEQIDLRRRLEQEF 960
           FITDSDASGGDFWRERSGEHTQETNSPHSLKKDVENMGKEELQKVLFEQIDLRRRLEQEF
Sbjct: 901 FITDSDASGGDFWRERSGEHTQETNSPHSLKKDVENMGKEELQKVLFEQIDLRRRLEQEF 960

Query: 961 QVLKGNTSFPVF 972
           QVLKGNTSFPVF
Sbjct: 961 QVLKGNTSFPVF 972


>gi|73476377 LBXCOR1 homolog [Homo sapiens]
          Length = 921

 Score =  458 bits (1179), Expect = e-128
 Identities = 337/807 (41%), Positives = 385/807 (47%), Gaps = 104/807 (12%)

Query: 28  QPRPGHANLKPNQVGQVILYGIPIVSLVIDGQERLCLAQISNTLLKNFSYNEIHNRRVAL 87
           QP  G + LKPNQVG+  LYG+PIVSLVIDGQERLCLAQISNTLLKN+SYNEIHNRRVAL
Sbjct: 55  QPYSGSSALKPNQVGETSLYGVPIVSLVIDGQERLCLAQISNTLLKNYSYNEIHNRRVAL 114

Query: 88  GITCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERLCKSFLGENRPPKLPDNFAFDV 147
           GITCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERLCKSFLGE++PPKLP+NFAFDV
Sbjct: 115 GITCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERLCKSFLGEHKPPKLPENFAFDV 174

Query: 148 SHECAWGCRGSFIPARYNSSRAKCIKCSYCNMYFSPNKFIFHSHRTPDAKYTQPDAANFN 207
            HECAWG RGSFIPARYNSSRAKCIKC YC+MYFSPNKFIFHSHRTPDAKYTQPDAANFN
Sbjct: 175 VHECAWGSRGSFIPARYNSSRAKCIKCGYCSMYFSPNKFIFHSHRTPDAKYTQPDAANFN 234

Query: 208 SWRRHLKLTDKSPQDELVFAWEDVKAMFNGGSRKRALPQPG------------------A 249
           SWRRHLKL+DKS  DEL  AWEDVKAMFNGG+R  A   PG                   
Sbjct: 235 SWRRHLKLSDKSATDELSHAWEDVKAMFNGGTRCGAEMAPGPPPHKSLRCGEDEAAGPPG 294

Query: 250 HPACHPLSSVKAAAVAAAAAVAGG-GGLLGPHLLGAPPPPPP--------PPPPLAELAG 300
            P  HP   +  A  A+  A  GG GG  G       P P          PPP      G
Sbjct: 295 PPPPHPQRGLGLATGASGPAGPGGPGGGAGVRSYPVIPVPSKGFGLLQKLPPPLFPHPYG 354

Query: 301 APHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTG-GGGAGGGCVAG 359
            P A    P+ DD               L A          SGG G G GGGAGG   + 
Sbjct: 355 FPTAFGLCPKKDD-------------PVLGAGEPKGGPGTGSGGGGAGTGGGAGGPGASH 401

Query: 360 VGVGAGAGAGAGAGAKGPR----SYPVIPVPSKGSFGGVLQKFP---GCGGLFPHPYTFP 412
           +  GAGAG G GA   G +    +     V +  +   V   FP      G  P P ++P
Sbjct: 402 LPPGAGAGPGGGAMFWGHQPSGAAKDAAAVAAAAAAATVYPTFPMFWPAAGSLPVP-SYP 460

Query: 413 AA-AAAFSLCHKKEDAGAAAEALGGAGA----GGAGAAPKAGLSGLFWPAGRKDAFYPPF 467
           AA + A ++      A AAA A  G+GA     GA  A ++GL       G ++    P 
Sbjct: 461 AAQSQAKAVAAAVAAAAAAAAAAAGSGAPEPLDGAEPAKESGL-------GAEERC--PS 511

Query: 468 CMFWPPRTPGG----LPVPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSA 523
            +   P    G    LP P    PPP PP A     G   +  R    D        GSA
Sbjct: 512 ALSRGPLDEDGTDEALPPPLAPLPPPPPPPA---RKGSYVSAFRPVVKDTESIAKLYGSA 568

Query: 524 EAAPPPGQPPQVVANGPGSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAA 583
             A            GP  GP P AG  G     + SP   S G  S  S  P    A  
Sbjct: 569 REA---------YGAGPARGPGPGAGSGG-----YVSPDFLSEGSSSYNSASPDVDTADE 614

Query: 584 GAGAAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGAS 643
                 +   P          P       AGGG         P G +      A   GA 
Sbjct: 615 PEVDVESNRFPDDEDAQEETEP---SAPSAGGG---------PDGEQPTGPPSATSSGAD 662

Query: 644 --AGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPPPPP 701
             A +P      P     P               L+  P +    G   +    P  P  
Sbjct: 663 GPANSPDGGSPRPRRRLGPPPAGRPAFGDLAAEDLVRRPERSPPSGGGGYELREPCGPLG 722

Query: 702 PPPPPLAQHP----HHRGLLSPGGTSCSYPSEDSSEDEDDEEEEQEV-DVEGHKP-PEGE 755
            P P     P    H +      G + SY     + + D E+      D+E  K  P+  
Sbjct: 723 GPAPAKVFAPERDEHVKSAAVALGPAASYVCTPEAHEPDKEDNHSPADDLETRKSYPDQR 782

Query: 756 EEEEGRDPDDDEEEDEETEVLLGDPLV 782
              +    + D  ED  T  + G  LV
Sbjct: 783 SISQPSPANTDRGEDGLTLDVTGTHLV 809



 Score =  115 bits (287), Expect = 3e-25
 Identities = 166/628 (26%), Positives = 225/628 (35%), Gaps = 164/628 (26%)

Query: 422 HKKEDAGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPV 481
           H +   G A  A G AG GG G    AG+             YP       P    G  +
Sbjct: 299 HPQRGLGLATGASGPAGPGGPGGG--AGVRS-----------YPVI-----PVPSKGFGL 340

Query: 482 PTYLQPP--PQP---PSALG-CALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQV 535
              L PP  P P   P+A G C   + P L         EP G  G+       G     
Sbjct: 341 LQKLPPPLFPHPYGFPTAFGLCPKKDDPVL------GAGEPKGGPGTGSGGGGAGTGGG- 393

Query: 536 VANGPGSGPPPPAGGAGSRDALFESPPGGSG---GDCSAGSTPPADSVAAAGAGAAAAGS 592
            A GPG+   PP  GAG         PGG     G   +G+   A +VAAA A A    +
Sbjct: 394 -AGGPGASHLPPGAGAG---------PGGGAMFWGHQPSGAAKDAAAVAAAAAAATVYPT 443

Query: 593 ----GPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPH 648
                PA   +P P +P      KA                   A ++A    A+A A  
Sbjct: 444 FPMFWPAAGSLPVPSYPAAQSQAKAV------------------AAAVAAAAAAAAAAAG 485

Query: 649 SAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPL- 707
           S    P     P          + PS L   P   DE G++   P P  P PPPPPPP  
Sbjct: 486 SGAPEPLDGAEPAKESGLGAEERCPSALSRGPL--DEDGTDEALPPPLAPLPPPPPPPAR 543

Query: 708 ------------------------AQHPHHRGLL---SPGGTSCSYPSED---------- 730
                                   A+  +  G      PG  S  Y S D          
Sbjct: 544 KGSYVSAFRPVVKDTESIAKLYGSAREAYGAGPARGPGPGAGSGGYVSPDFLSEGSSSYN 603

Query: 731 SSEDEDDEEEEQEVDVEGHKPPEGEEEEE---------GRDPDDDEEEDEETEVLLG--- 778
           S+  + D  +E EVDVE ++ P+ E+ +E         G  PD ++     +    G   
Sbjct: 604 SASPDVDTADEPEVDVESNRFPDDEDAQEETEPSAPSAGGGPDGEQPTGPPSATSSGADG 663

Query: 779 ---DPLVGGGRFLQGRGPSEKG-------SSRDRAPAVAGAFPLGLNSSRLLQEDGKLGD 828
               P  G  R  +  GP   G       ++ D       + P G     L +  G LG 
Sbjct: 664 PANSPDGGSPRPRRRLGPPPAGRPAFGDLAAEDLVRRPERSPPSGGGGYELREPCGPLGG 723

Query: 829 PGSDLPPPPPPPLAPQK---------ASGGGSSSPGSP-VHHPSLEEQPSYKDSQKTKEN 878
           P       P    AP++         A G  +S   +P  H P  E+  S  D  +T++ 
Sbjct: 724 PA------PAKVFAPERDEHVKSAAVALGPAASYVCTPEAHEPDKEDNHSPADDLETRK- 776

Query: 879 NQVIVSTKDDNSFSDKNKEHSFFITDSDASGGDFWRERSGEHTQETNSPHSLKKDVENMG 938
                S  D  S S  +  +    TD    G           T +    H ++KD+EN+ 
Sbjct: 777 -----SYPDQRSISQPSPAN----TDRGEDG----------LTLDVTGTHLVEKDIENLA 817

Query: 939 KEELQKVLFEQIDLRRRLEQEFQVLKGN 966
           +EELQK+L EQ++LR++LE+EFQ LK N
Sbjct: 818 REELQKLLLEQMELRKKLEREFQSLKDN 845


>gi|4506967 v-ski sarcoma viral oncogene homolog [Homo sapiens]
          Length = 728

 Score =  132 bits (332), Expect = 2e-30
 Identities = 83/230 (36%), Positives = 123/230 (53%), Gaps = 24/230 (10%)

Query: 43  QVILYGIPIVSLVIDGQERLCLAQISNTLLKNFSYNEIHNRRVALGITCVQCTPVQLEIL 102
           + +L G  I   V+ G++RLCL QI N++L++FS  +I+     L I C +CT  QLEIL
Sbjct: 102 ETVLEGETISCFVVGGEKRLCLPQILNSVLRDFSLQQINAVCDELHIYCSRCTADQLEIL 161

Query: 103 RRAGAMPISSRRCGMITKREAERLCKSFL-GENRPPKLPDNFAFD-------------VS 148
           +  G +P S+  CG+ITK +AERLC + L G   PP      A               V 
Sbjct: 162 KVMGILPFSAPSCGLITKTDAERLCNALLYGGAYPPPCKKELAASLALGLELSERSVRVY 221

Query: 149 HECAWGCRGSFIPARYNSSRAKCIKCSYCNMYFSPNKFIFHSHRTPDAK--YTQPDAANF 206
           HEC   C+G  +P  Y+S  A CI+C  C + + P+KF+ HSH+  + +  +   D+AN 
Sbjct: 222 HECFGKCKGLLVPELYSSPSAACIQCLDCRLMYPPHKFVVHSHKALENRTCHWGFDSAN- 280

Query: 207 NSWRRHLKL----TDKSPQDELVFAWEDVKAMFNGGSR-KRALPQPGAHP 251
             WR ++ L    T K  Q  L    +DVK  F+ G++ KR +P+  + P
Sbjct: 281 --WRAYILLSQDYTGKEEQARLGRCLDDVKEKFDYGNKYKRRVPRVSSEP 328


>gi|223029422 SKI-like isoform 3 [Homo sapiens]
          Length = 664

 Score =  121 bits (304), Expect = 3e-27
 Identities = 83/252 (32%), Positives = 119/252 (47%), Gaps = 30/252 (11%)

Query: 12  ILLASPSSAFQPDTLSQPRPGHANLKPNQVGQVILYGIPIVSLVIDGQERLCLAQISNTL 71
           + L  PS    P  L  P      L      Q +L G  I    + G++RLCL Q+ N++
Sbjct: 100 VFLPLPSPQVLPGPLLIPSDSSTELT-----QTVLEGESISCFQVGGEKRLCLPQVLNSV 154

Query: 72  LKNFSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERLCKSFL 131
           L+ F+  +I+     L I C +CT  QL IL+  G +P ++  CG+IT  +A+RLC + L
Sbjct: 155 LREFTLQQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALL 214

Query: 132 GENRPPKLPDN-----------------FAFDVSHECAWGCRGSFIPARYNSSRAKCIKC 174
              RP   P N                  AF+V HEC   C+G F P  Y    A CI+C
Sbjct: 215 ---RPRTFPQNGSVLPAKSSLAQLKETGSAFEVEHECLGKCQGLFAPQFYVQPDAPCIQC 271

Query: 175 SYCNMYFSPNKFIFHSHRTPDAKYTQPDAANFNSWRRHLKLTDK---SPQD-ELVFAWED 230
             C   F+P  F+ HSHR+PD K T         W  +L +  K   +P++ +L    E+
Sbjct: 272 LECCGMFAPQTFVMHSHRSPD-KRTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEE 330

Query: 231 VKAMFNGGSRKR 242
           +K  F+  S KR
Sbjct: 331 MKEKFSMRSGKR 342


>gi|223029420 SKI-like isoform 2 [Homo sapiens]
          Length = 638

 Score =  121 bits (304), Expect = 3e-27
 Identities = 83/252 (32%), Positives = 119/252 (47%), Gaps = 30/252 (11%)

Query: 12  ILLASPSSAFQPDTLSQPRPGHANLKPNQVGQVILYGIPIVSLVIDGQERLCLAQISNTL 71
           + L  PS    P  L  P      L      Q +L G  I    + G++RLCL Q+ N++
Sbjct: 120 VFLPLPSPQVLPGPLLIPSDSSTELT-----QTVLEGESISCFQVGGEKRLCLPQVLNSV 174

Query: 72  LKNFSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERLCKSFL 131
           L+ F+  +I+     L I C +CT  QL IL+  G +P ++  CG+IT  +A+RLC + L
Sbjct: 175 LREFTLQQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALL 234

Query: 132 GENRPPKLPDN-----------------FAFDVSHECAWGCRGSFIPARYNSSRAKCIKC 174
              RP   P N                  AF+V HEC   C+G F P  Y    A CI+C
Sbjct: 235 ---RPRTFPQNGSVLPAKSSLAQLKETGSAFEVEHECLGKCQGLFAPQFYVQPDAPCIQC 291

Query: 175 SYCNMYFSPNKFIFHSHRTPDAKYTQPDAANFNSWRRHLKLTDK---SPQD-ELVFAWED 230
             C   F+P  F+ HSHR+PD K T         W  +L +  K   +P++ +L    E+
Sbjct: 292 LECCGMFAPQTFVMHSHRSPD-KRTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEE 350

Query: 231 VKAMFNGGSRKR 242
           +K  F+  S KR
Sbjct: 351 MKEKFSMRSGKR 362


>gi|223029418 SKI-like isoform 1 [Homo sapiens]
          Length = 684

 Score =  121 bits (304), Expect = 3e-27
 Identities = 83/252 (32%), Positives = 119/252 (47%), Gaps = 30/252 (11%)

Query: 12  ILLASPSSAFQPDTLSQPRPGHANLKPNQVGQVILYGIPIVSLVIDGQERLCLAQISNTL 71
           + L  PS    P  L  P      L      Q +L G  I    + G++RLCL Q+ N++
Sbjct: 120 VFLPLPSPQVLPGPLLIPSDSSTELT-----QTVLEGESISCFQVGGEKRLCLPQVLNSV 174

Query: 72  LKNFSYNEIHNRRVALGITCVQCTPVQLEILRRAGAMPISSRRCGMITKREAERLCKSFL 131
           L+ F+  +I+     L I C +CT  QL IL+  G +P ++  CG+IT  +A+RLC + L
Sbjct: 175 LREFTLQQINTVCDELYIYCSRCTSDQLHILKVLGILPFNAPSCGLITLTDAQRLCNALL 234

Query: 132 GENRPPKLPDN-----------------FAFDVSHECAWGCRGSFIPARYNSSRAKCIKC 174
              RP   P N                  AF+V HEC   C+G F P  Y    A CI+C
Sbjct: 235 ---RPRTFPQNGSVLPAKSSLAQLKETGSAFEVEHECLGKCQGLFAPQFYVQPDAPCIQC 291

Query: 175 SYCNMYFSPNKFIFHSHRTPDAKYTQPDAANFNSWRRHLKLTDK---SPQD-ELVFAWED 230
             C   F+P  F+ HSHR+PD K T         W  +L +  K   +P++ +L    E+
Sbjct: 292 LECCGMFAPQTFVMHSHRSPD-KRTCHWGFESAKWHCYLHVNQKYLGTPEEKKLKIILEE 350

Query: 231 VKAMFNGGSRKR 242
           +K  F+  S KR
Sbjct: 351 MKEKFSMRSGKR 362


>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
          Length = 2285

 Score = 98.6 bits (244), Expect = 3e-20
 Identities = 178/746 (23%), Positives = 247/746 (33%), Gaps = 227/746 (30%)

Query: 261 AAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPPPLAELAGAPHAHHKRPRFDDDDDSLQE 320
           AA VA AAA +          LG PPPPPP     +EL        K+      +++  E
Sbjct: 2   AAQVAPAAASS----------LGNPPPPPP-----SEL--------KKAEQQQREEAGGE 38

Query: 321 AAVVAAAS---LSAAAASLSVAAASG-----------GAGTGGGGAGGGCVAGVGVGA-- 364
           AA  AAA    + AAA   S   A G           GA + GGG GGG  +G G GA  
Sbjct: 39  AAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEP 98

Query: 365 --------------------------GAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKF 398
                                     G G+  G GA    +   +P P+ G FG    + 
Sbjct: 99  DLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYG-FGQPYGRS 157

Query: 399 PGCGGLFPHPYTFPAAAAAFSLCH-KKEDAGAAAEALGGAGAGGAGAAPKAGLSGLFWPA 457
           P             AAAA F   H  ++  G AA   GG G     A P+       +P 
Sbjct: 158 PSA--------VAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPN 209

Query: 458 GRKDAFYPPFCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPG 517
            + +++YP    +                PPP P  AL    G +P              
Sbjct: 210 HQYNSYYPNRSAY----------------PPPAPAYALSSPRGGTPG------------S 241

Query: 518 GAAGSAEAAPPPGQPPQVVANGP----------GSGPPPPAGGAGSR-------DALFES 560
           GAA +A + PPP       ++            G G P  AGG   +       + L  S
Sbjct: 242 GAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTS 301

Query: 561 P------PGGSGGDCSAG------STPPADSV-----AAAGAGAAAAGSGPAGSRVPAPH 603
           P       G  GGD S G         PAD       AAA A AAAA SG A  R    H
Sbjct: 302 PSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQR---SH 358

Query: 604 HPHLLEGRKAGGG----------------------------------------SYHHSSA 623
           H  +  G   GGG                                           H   
Sbjct: 359 HAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYP 418

Query: 624 FRPVGGKDDAESLAKLHG----ASAGAPHSAQTHPHHHHHPHHHHHHHHPP----QPPSP 675
            +P G +        + G    A  G  ++ Q  P+    P  +      P    Q P P
Sbjct: 419 GQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHP 478

Query: 676 LLLLPPQPDEPGSERHHPAP---PPPPPPPPPPPLAQHPHHRGLLSP--GGTSCSYPSED 730
               PP   +P S+  H  P     P   PP    +Q P+ +    P    +   YPS+ 
Sbjct: 479 QQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQ 538

Query: 731 SSEDEDDEEEEQEVDVEGHKPPEGEE---------EEEGRDPDDDEEEDEETEVLLGDPL 781
           S+  +  + +      +   P + ++          ++   P    ++ ++T        
Sbjct: 539 STTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQT-------- 590

Query: 782 VGGGRFLQGRGPSEKGSSRDRAPAVAGAFPLGLNSSRLLQEDGKL---GDPGS------- 831
                + Q R P  +  S+D   + A + P  + SS+  QED  L     P S       
Sbjct: 591 ----AYSQQRFPPPQELSQDSFGSQASSAP-SMTSSKGGQEDMNLSLQSRPSSLPDLSGS 645

Query: 832 --DLPPPPPPPLAPQKASGGGSSSPG 855
             DLP      L+P  ++ G SSS G
Sbjct: 646 IDDLPMGTEGALSPGVSTSGISSSQG 671



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 114/491 (23%), Positives = 162/491 (32%), Gaps = 47/491 (9%)

Query: 255 PLSSVKAAAVAAAAAV----AGGGGLLGPHLLGAPPPPPPPPPPLAELAGAP---HAHHK 307
           P SS  A++ +++ A     A GGG  GP   G   P P   P L +L  +P     +  
Sbjct: 253 PSSSASASSSSSSFAQQRFGAMGGG--GPSAAGGGTPQPTATPTLNQLLTSPSSARGYQG 310

Query: 308 RPRFD-----DDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGV 362
            P  D      D  + +  A +A+    AAAA+ + AAASGGA            A +  
Sbjct: 311 YPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHH------APMSP 364

Query: 363 GAGAGAGAGAGAKGPRSYP------VIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAA 416
           G+  G G         S P      + P P  G+     Q+ P  G    H Y      +
Sbjct: 365 GSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGS 424

Query: 417 AFSLCHKKEDAGAAAEALGGA---------GAGGAGAAPKAGLSGLF-WPAGRKDAFYPP 466
                +     G A  A+GG          G  G     + G +  +   +       PP
Sbjct: 425 QTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPP 484

Query: 467 FCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAA 526
           +    P +TP   P     QP  QPP         S    +        P  +  S    
Sbjct: 485 YSQQPPSQTPHAQP-SYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQ 543

Query: 527 PPPGQPP--QVVANGP--GSGPPPPAGGAGSRDALFESPPGGSGGDC--SAGSTPPADSV 580
            P  QPP  Q  A  P     P  PA    S+ A +  P          S    PP   +
Sbjct: 544 HPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQEL 603

Query: 581 AAAGAGAAAAGSGPAGSRVPAPHHPHL-LEGRKAGGGSYHHSSAFRPVGGKDDAESLAKL 639
           +    G+ A+ +    S        +L L+ R +       S    P+G +         
Sbjct: 604 SQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVST 663

Query: 640 HGASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLL-LPPQPDEPGSERHHPAPPPP 698
            G S+      Q++P       H   H    + PSP  +  P    +  S    PA  P 
Sbjct: 664 SGISSS--QGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPG 721

Query: 699 PPPPPPPPLAQ 709
              PP PP  Q
Sbjct: 722 NQMPPRPPSGQ 732



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 64/283 (22%), Positives = 94/283 (33%), Gaps = 31/283 (10%)

Query: 486  QPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQ-PPQVVANGPGSGP 544
            QP  QPPS  G    + P   +     +AE G       A+ P  Q PP    +   S  
Sbjct: 1127 QPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVG 1186

Query: 545  PPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHH 604
               A   GS D+ F+     +    + G  P  ++    G  +      P GS       
Sbjct: 1187 IQDAFNDGS-DSTFQK---RNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSM------ 1236

Query: 605  PHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTHPHHHHHPHHHH 664
                  RKA G     SS   P GG  D  S A   G    A    Q +P+   +     
Sbjct: 1237 ------RKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRT 1290

Query: 665  HHHHPPQ------PPSPLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQHPHHRGLLS 718
                 P+       P P L+    P  P S  + P+  PP          +H  +    S
Sbjct: 1291 EPGIGPEGNMSTGAPQPNLM----PSNPDSGMYSPSRYPPQQQQQQQ--QRHDSYGNQFS 1344

Query: 719  PGGT--SCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEE 759
              GT     +PS+ ++  +  ++  +      + PP    E E
Sbjct: 1345 TQGTPSGSPFPSQQTTMYQQQQQNYKRPMDGTYGPPAKRHEGE 1387



 Score = 31.6 bits (70), Expect = 3.9
 Identities = 39/153 (25%), Positives = 55/153 (35%), Gaps = 17/153 (11%)

Query: 446 PKAGLSGLFWPAGRKDAFY-----PPFCMFWPPR----TPGGLPV-PTYLQPPPQPPSAL 495
           P AG++G   P G     +     PP+    P R    + G  P  P     PPQ    +
Sbjct: 824 PSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQ----V 879

Query: 496 GCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPPPAGGAGSRD 555
           G  +   P  + +   + A     A ++    PPG P        G+G PP   G  S  
Sbjct: 880 GSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTG-PPYGQGINSMA 938

Query: 556 ALF--ESPPGGSGGDCSAGSTPPADSVAAAGAG 586
            +   + PP   GG  +  S   A S    G G
Sbjct: 939 GMINPQGPPYSMGGTMANNSAGMAASPEMMGLG 971


>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
          Length = 2068

 Score = 98.6 bits (244), Expect = 3e-20
 Identities = 178/746 (23%), Positives = 247/746 (33%), Gaps = 227/746 (30%)

Query: 261 AAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPPPLAELAGAPHAHHKRPRFDDDDDSLQE 320
           AA VA AAA +          LG PPPPPP     +EL        K+      +++  E
Sbjct: 2   AAQVAPAAASS----------LGNPPPPPP-----SEL--------KKAEQQQREEAGGE 38

Query: 321 AAVVAAAS---LSAAAASLSVAAASG-----------GAGTGGGGAGGGCVAGVGVGA-- 364
           AA  AAA    + AAA   S   A G           GA + GGG GGG  +G G GA  
Sbjct: 39  AAAAAAAERGEMKAAAGQESEGPAVGPPQPLGKELQDGAESNGGGGGGGAGSGGGPGAEP 98

Query: 365 --------------------------GAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKF 398
                                     G G+  G GA    +   +P P+ G FG    + 
Sbjct: 99  DLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYG-FGQPYGRS 157

Query: 399 PGCGGLFPHPYTFPAAAAAFSLCH-KKEDAGAAAEALGGAGAGGAGAAPKAGLSGLFWPA 457
           P             AAAA F   H  ++  G AA   GG G     A P+       +P 
Sbjct: 158 PSA--------VAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYAGPQQNSHDHGFPN 209

Query: 458 GRKDAFYPPFCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPG 517
            + +++YP    +                PPP P  AL    G +P              
Sbjct: 210 HQYNSYYPNRSAY----------------PPPAPAYALSSPRGGTPG------------S 241

Query: 518 GAAGSAEAAPPPGQPPQVVANGP----------GSGPPPPAGGAGSR-------DALFES 560
           GAA +A + PPP       ++            G G P  AGG   +       + L  S
Sbjct: 242 GAAAAAGSKPPPSSSASASSSSSSFAQQRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTS 301

Query: 561 P------PGGSGGDCSAG------STPPADSV-----AAAGAGAAAAGSGPAGSRVPAPH 603
           P       G  GGD S G         PAD       AAA A AAAA SG A  R    H
Sbjct: 302 PSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQR---SH 358

Query: 604 HPHLLEGRKAGGG----------------------------------------SYHHSSA 623
           H  +  G   GGG                                           H   
Sbjct: 359 HAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYP 418

Query: 624 FRPVGGKDDAESLAKLHG----ASAGAPHSAQTHPHHHHHPHHHHHHHHPP----QPPSP 675
            +P G +        + G    A  G  ++ Q  P+    P  +      P    Q P P
Sbjct: 419 GQPYGSQTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHP 478

Query: 676 LLLLPPQPDEPGSERHHPAP---PPPPPPPPPPPLAQHPHHRGLLSP--GGTSCSYPSED 730
               PP   +P S+  H  P     P   PP    +Q P+ +    P    +   YPS+ 
Sbjct: 479 QQQQPPYSQQPPSQTPHAQPSYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQ 538

Query: 731 SSEDEDDEEEEQEVDVEGHKPPEGEE---------EEEGRDPDDDEEEDEETEVLLGDPL 781
           S+  +  + +      +   P + ++          ++   P    ++ ++T        
Sbjct: 539 STTQQHPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQT-------- 590

Query: 782 VGGGRFLQGRGPSEKGSSRDRAPAVAGAFPLGLNSSRLLQEDGKL---GDPGS------- 831
                + Q R P  +  S+D   + A + P  + SS+  QED  L     P S       
Sbjct: 591 ----AYSQQRFPPPQELSQDSFGSQASSAP-SMTSSKGGQEDMNLSLQSRPSSLPDLSGS 645

Query: 832 --DLPPPPPPPLAPQKASGGGSSSPG 855
             DLP      L+P  ++ G SSS G
Sbjct: 646 IDDLPMGTEGALSPGVSTSGISSSQG 671



 Score = 47.8 bits (112), Expect = 5e-05
 Identities = 114/491 (23%), Positives = 162/491 (32%), Gaps = 47/491 (9%)

Query: 255 PLSSVKAAAVAAAAAV----AGGGGLLGPHLLGAPPPPPPPPPPLAELAGAP---HAHHK 307
           P SS  A++ +++ A     A GGG  GP   G   P P   P L +L  +P     +  
Sbjct: 253 PSSSASASSSSSSFAQQRFGAMGGG--GPSAAGGGTPQPTATPTLNQLLTSPSSARGYQG 310

Query: 308 RPRFD-----DDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGV 362
            P  D      D  + +  A +A+    AAAA+ + AAASGGA            A +  
Sbjct: 311 YPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASGGAQQRSHH------APMSP 364

Query: 363 GAGAGAGAGAGAKGPRSYP------VIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAA 416
           G+  G G         S P      + P P  G+     Q+ P  G    H Y      +
Sbjct: 365 GSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGS 424

Query: 417 AFSLCHKKEDAGAAAEALGGA---------GAGGAGAAPKAGLSGLF-WPAGRKDAFYPP 466
                +     G A  A+GG          G  G     + G +  +   +       PP
Sbjct: 425 QTPQRYPMTMQGRAQSAMGGLSYTQQIPPYGQQGPSGYGQQGQTPYYNQQSPHPQQQQPP 484

Query: 467 FCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAA 526
           +    P +TP   P     QP  QPP         S    +        P  +  S    
Sbjct: 485 YSQQPPSQTPHAQP-SYQQQPQSQPPQLQSSQPPYSQQPSQPPHQQSPAPYPSQQSTTQQ 543

Query: 527 PPPGQPP--QVVANGP--GSGPPPPAGGAGSRDALFESPPGGSGGDC--SAGSTPPADSV 580
            P  QPP  Q  A  P     P  PA    S+ A +  P          S    PP   +
Sbjct: 544 HPQSQPPYSQPQAQSPYQQQQPQQPAPSTLSQQAAYPQPQSQQSQQTAYSQQRFPPPQEL 603

Query: 581 AAAGAGAAAAGSGPAGSRVPAPHHPHL-LEGRKAGGGSYHHSSAFRPVGGKDDAESLAKL 639
           +    G+ A+ +    S        +L L+ R +       S    P+G +         
Sbjct: 604 SQDSFGSQASSAPSMTSSKGGQEDMNLSLQSRPSSLPDLSGSIDDLPMGTEGALSPGVST 663

Query: 640 HGASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLL-LPPQPDEPGSERHHPAPPPP 698
            G S+      Q++P       H   H    + PSP  +  P    +  S    PA  P 
Sbjct: 664 SGISSS--QGEQSNPAQSPFSPHTSPHLPGIRGPSPSPVGSPASVAQSRSGPLSPAAVPG 721

Query: 699 PPPPPPPPLAQ 709
              PP PP  Q
Sbjct: 722 NQMPPRPPSGQ 732



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 64/282 (22%), Positives = 98/282 (34%), Gaps = 48/282 (17%)

Query: 671  QPPSPL---LLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQHPHHRGLLSPGGTSCSYP 727
            QPPSP     +  PQ  +  S          PP P   P +Q P   G+           
Sbjct: 1131 QPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVGIQDA 1190

Query: 728  SEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGR---DPDDDEEEDEETEVLLGDPLVGG 784
              D S D   ++        G++P     +  GR   +P+ D       +    DP +  
Sbjct: 1191 FNDGS-DSTFQKRNSMTPNPGYQPSMNTSDMMGRMSYEPNKD-PYGSMRKAPGSDPFMSS 1248

Query: 785  GRFLQG-RGPSEKGSSRDRAPAVAGA-------FPLGLNSSRLLQEDGKLGDPGSDLPPP 836
            G   QG  G      SR   P +          +P G    R+  E G +G  G+     
Sbjct: 1249 G---QGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRTEPG-IGPEGNMSTGA 1304

Query: 837  PPPPLAPQKASGGGSSSPGSPVHHPSLEEQPSYKDSQKTKENNQVIVSTKDDNSFSDKNK 896
            P P L P        S+P S ++ PS    P  +  Q+ + ++         N FS    
Sbjct: 1305 PQPNLMP--------SNPDSGMYSPS-RYPPQQQQQQQQRHDSY-------GNQFS---- 1344

Query: 897  EHSFFITDSDASGGDFWRERSG--EHTQETNSPHSLKKDVEN 936
                  T    SG  F  +++   +  Q+ +SP  L + +EN
Sbjct: 1345 ------TQGTPSGSPFPSQQTTMYQQQQQVSSPAPLPRPMEN 1380



 Score = 31.6 bits (70), Expect = 3.9
 Identities = 39/153 (25%), Positives = 55/153 (35%), Gaps = 17/153 (11%)

Query: 446 PKAGLSGLFWPAGRKDAFY-----PPFCMFWPPR----TPGGLPV-PTYLQPPPQPPSAL 495
           P AG++G   P G     +     PP+    P R    + G  P  P     PPQ    +
Sbjct: 824 PSAGMAGGINPMGAGGQMHGQPGIPPYGTLPPGRMSHASMGNRPYGPNMANMPPQ----V 879

Query: 496 GCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPPPAGGAGSRD 555
           G  +   P  + +   + A     A ++    PPG P        G+G PP   G  S  
Sbjct: 880 GSGMCPPPGGMNRKTQETAVAMHVAANSIQNRPPGYPNMNQGGMMGTG-PPYGQGINSMA 938

Query: 556 ALF--ESPPGGSGGDCSAGSTPPADSVAAAGAG 586
            +   + PP   GG  +  S   A S    G G
Sbjct: 939 GMINPQGPPYSMGGTMANNSAGMAASPEMMGLG 971



 Score = 31.2 bits (69), Expect = 5.1
 Identities = 54/220 (24%), Positives = 73/220 (33%), Gaps = 27/220 (12%)

Query: 486  QPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQ-PPQVVANGPGSGP 544
            QP  QPPS  G    + P   +     +AE G       A+ P  Q PP    +   S  
Sbjct: 1127 QPKIQPPSPAGSGSMQGPQTPQSTSSSMAEGGDLKPPTPASTPHSQIPPLPGMSRSNSVG 1186

Query: 545  PPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHH 604
               A   GS D+ F+     +    + G  P  ++    G  +      P GS       
Sbjct: 1187 IQDAFNDGS-DSTFQK---RNSMTPNPGYQPSMNTSDMMGRMSYEPNKDPYGSM------ 1236

Query: 605  PHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTHPHHHHHPHHHH 664
                  RKA G     SS   P GG  D  S A   G    A    Q +P+   +     
Sbjct: 1237 ------RKAPGSDPFMSSGQGPNGGMGDPYSRAAGPGLGNVAMGPRQHYPYGGPYDRVRT 1290

Query: 665  HHHHPPQ------PPSPLLLLPPQPDEPGSERHHPAPPPP 698
                 P+       P P L+    P  P S  + P+  PP
Sbjct: 1291 EPGIGPEGNMSTGAPQPNLM----PSNPDSGMYSPSRYPP 1326


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 92.8 bits (229), Expect = 1e-18
 Identities = 136/570 (23%), Positives = 172/570 (30%), Gaps = 155/570 (27%)

Query: 285 PPPPPPPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAA---VVAAASLSAAAA---SLSV 338
           PPPP PPPPP   LA       ++P  +  + + + A    +     L        S  +
Sbjct: 4   PPPPAPPPPPTFALANT-----EKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPI 58

Query: 339 AAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKF 398
                GAG GGGG G G   G G G G G G   G  GP                     
Sbjct: 59  LDKPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGP--------------------- 97

Query: 399 PGCGGLFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGAGGAGAAPKAGLSGLFWPAG 458
           PG GGLF             S  ++  D+G              G+ P      L  P G
Sbjct: 98  PGLGGLFQ-----AGMPKLRSTANRDNDSG--------------GSRPP-----LLPPGG 133

Query: 459 RKDAFYPPFCMFWPPRTPGGLPVPT--YLQPPPQPPSALGCALGESPALLRQAFLDLAEP 516
           R  +  P    F PP  PG  PVP+  +   PP+P                     +  P
Sbjct: 134 RSTSAKP----FSPPSGPGRFPVPSPGHRSGPPEPQRN-----------------RMPPP 172

Query: 517 GGAAGSAEAAPPPGQP--PQVVANGPGSGPPPPAGGAGSRDALFESPPGGSGGDCSAGST 574
               GS   + PP  P  P+ + + P +   PP              PGG        + 
Sbjct: 173 RPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPV-------------PGGPRQPSPGPTP 219

Query: 575 PPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAE 634
           PP         G  +    P  S  P  + P L                  P    DD  
Sbjct: 220 PPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPP---------------TPSRALDD-- 262

Query: 635 SLAKLHGASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPA 694
                              P   + P  H     PP P +     PP P  P       A
Sbjct: 263 -------------KPPPPPPPVGNRPSIHREAVPPPPPQNN---KPPVPSTPRPSASSQA 306

Query: 695 PPPPPPP--PPPPPLAQHPHHRGLLSPGGTSCSYPSEDSSEDEDDEEEEQEVDVEGHKPP 752
           PPPPPPP  P PPPL                   P   S  DE     ++ + +    PP
Sbjct: 307 PPPPPPPSRPGPPPL-------------------PPSSSGNDETPRLPQRNLSLSSSTPP 347

Query: 753 EGEEEEEGRDPDDDEEEDEETEVLLGDPLVGGGRFLQGRGPSEKGSSRDRAPAVAGAFP- 811
                  G  P    E        + DP  G    L    P  +  S  RA       P 
Sbjct: 348 LPSPGRSGPLPPPPSERPPPP---VRDP-PGRSGPLPPPPPVSRNGSTSRALPATPQLPS 403

Query: 812 -LGLNSSRLLQEDGKLGD-PGSDLPPPPPP 839
             G++S R         D P +  PPPPPP
Sbjct: 404 RSGVDSPRSGPRPPLPPDRPSAGAPPPPPP 433



 Score = 33.9 bits (76), Expect = 0.78
 Identities = 29/96 (30%), Positives = 38/96 (39%), Gaps = 8/96 (8%)

Query: 473 PRTPGGLPVPTYLQPPP---QPPSALGCALGESPALLRQAFLDLAEPGGA---AGSAEAA 526
           P   G LP P   +PPP    PP   G  L   P + R      A P      + S   +
Sbjct: 351 PGRSGPLPPPPSERPPPPVRDPPGRSG-PLPPPPPVSRNGSTSRALPATPQLPSRSGVDS 409

Query: 527 PPPGQPPQVVANGPGSG-PPPPAGGAGSRDALFESP 561
           P  G  P +  + P +G PPPP      R+   +SP
Sbjct: 410 PRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSP 445



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 44/175 (25%), Positives = 59/175 (33%), Gaps = 36/175 (20%)

Query: 693 PAPPPPPPPPPPPPLAQHPHHRGLLSPGGTSCSYPSEDSSEDEDDEEEEQEVDVEGHKP- 751
           P PPPP PPPPP     +     L     T  +  +   S+    ++ ++ V  +   P 
Sbjct: 2   PVPPPPAPPPPPTFALANTEKPTL---NKTEQAGRNALLSDISKGKKLKKTVTNDRSAPI 58

Query: 752 ---PEGEEEEEGRDPDDDEEEDEETEVLLGDPLVGGGRFLQGRGPSEKGS-SRDRAPAVA 807
              P+G     G                 G    GGG F  G G    GS      P + 
Sbjct: 59  LDKPKGAGAGGG-----------------GGGFGGGGGFGGGGGGGGGGSFGGGGPPGLG 101

Query: 808 GAFPLGLNSSRLLQEDGKLGDPGSDLPPPPPPPLAPQKASGGGSSSPGSPVHHPS 862
           G F  G+   +L     +  D G   PP  PP         GG S+   P   PS
Sbjct: 102 GLFQAGM--PKLRSTANRDNDSGGSRPPLLPP---------GGRSTSAKPFSPPS 145


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 92.8 bits (229), Expect = 1e-18
 Identities = 136/570 (23%), Positives = 172/570 (30%), Gaps = 155/570 (27%)

Query: 285 PPPPPPPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAA---VVAAASLSAAAA---SLSV 338
           PPPP PPPPP   LA       ++P  +  + + + A    +     L        S  +
Sbjct: 4   PPPPAPPPPPTFALANT-----EKPTLNKTEQAGRNALLSDISKGKKLKKTVTNDRSAPI 58

Query: 339 AAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKF 398
                GAG GGGG G G   G G G G G G   G  GP                     
Sbjct: 59  LDKPKGAGAGGGGGGFGGGGGFGGGGGGGGGGSFGGGGP--------------------- 97

Query: 399 PGCGGLFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGAGGAGAAPKAGLSGLFWPAG 458
           PG GGLF             S  ++  D+G              G+ P      L  P G
Sbjct: 98  PGLGGLFQ-----AGMPKLRSTANRDNDSG--------------GSRPP-----LLPPGG 133

Query: 459 RKDAFYPPFCMFWPPRTPGGLPVPT--YLQPPPQPPSALGCALGESPALLRQAFLDLAEP 516
           R  +  P    F PP  PG  PVP+  +   PP+P                     +  P
Sbjct: 134 RSTSAKP----FSPPSGPGRFPVPSPGHRSGPPEPQRN-----------------RMPPP 172

Query: 517 GGAAGSAEAAPPPGQP--PQVVANGPGSGPPPPAGGAGSRDALFESPPGGSGGDCSAGST 574
               GS   + PP  P  P+ + + P +   PP              PGG        + 
Sbjct: 173 RPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPV-------------PGGPRQPSPGPTP 219

Query: 575 PPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAE 634
           PP         G  +    P  S  P  + P L                  P    DD  
Sbjct: 220 PPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPP---------------TPSRALDD-- 262

Query: 635 SLAKLHGASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPA 694
                              P   + P  H     PP P +     PP P  P       A
Sbjct: 263 -------------KPPPPPPPVGNRPSIHREAVPPPPPQNN---KPPVPSTPRPSASSQA 306

Query: 695 PPPPPPP--PPPPPLAQHPHHRGLLSPGGTSCSYPSEDSSEDEDDEEEEQEVDVEGHKPP 752
           PPPPPPP  P PPPL                   P   S  DE     ++ + +    PP
Sbjct: 307 PPPPPPPSRPGPPPL-------------------PPSSSGNDETPRLPQRNLSLSSSTPP 347

Query: 753 EGEEEEEGRDPDDDEEEDEETEVLLGDPLVGGGRFLQGRGPSEKGSSRDRAPAVAGAFP- 811
                  G  P    E        + DP  G    L    P  +  S  RA       P 
Sbjct: 348 LPSPGRSGPLPPPPSERPPPP---VRDP-PGRSGPLPPPPPVSRNGSTSRALPATPQLPS 403

Query: 812 -LGLNSSRLLQEDGKLGD-PGSDLPPPPPP 839
             G++S R         D P +  PPPPPP
Sbjct: 404 RSGVDSPRSGPRPPLPPDRPSAGAPPPPPP 433



 Score = 33.9 bits (76), Expect = 0.78
 Identities = 29/96 (30%), Positives = 38/96 (39%), Gaps = 8/96 (8%)

Query: 473 PRTPGGLPVPTYLQPPP---QPPSALGCALGESPALLRQAFLDLAEPGGA---AGSAEAA 526
           P   G LP P   +PPP    PP   G  L   P + R      A P      + S   +
Sbjct: 351 PGRSGPLPPPPSERPPPPVRDPPGRSG-PLPPPPPVSRNGSTSRALPATPQLPSRSGVDS 409

Query: 527 PPPGQPPQVVANGPGSG-PPPPAGGAGSRDALFESP 561
           P  G  P +  + P +G PPPP      R+   +SP
Sbjct: 410 PRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSP 445



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 44/175 (25%), Positives = 59/175 (33%), Gaps = 36/175 (20%)

Query: 693 PAPPPPPPPPPPPPLAQHPHHRGLLSPGGTSCSYPSEDSSEDEDDEEEEQEVDVEGHKP- 751
           P PPPP PPPPP     +     L     T  +  +   S+    ++ ++ V  +   P 
Sbjct: 2   PVPPPPAPPPPPTFALANTEKPTL---NKTEQAGRNALLSDISKGKKLKKTVTNDRSAPI 58

Query: 752 ---PEGEEEEEGRDPDDDEEEDEETEVLLGDPLVGGGRFLQGRGPSEKGS-SRDRAPAVA 807
              P+G     G                 G    GGG F  G G    GS      P + 
Sbjct: 59  LDKPKGAGAGGG-----------------GGGFGGGGGFGGGGGGGGGGSFGGGGPPGLG 101

Query: 808 GAFPLGLNSSRLLQEDGKLGDPGSDLPPPPPPPLAPQKASGGGSSSPGSPVHHPS 862
           G F  G+   +L     +  D G   PP  PP         GG S+   P   PS
Sbjct: 102 GLFQAGM--PKLRSTANRDNDSGGSRPPLLPP---------GGRSTSAKPFSPPS 145


>gi|118766337 zinc finger protein of the cerebellum 5 [Homo sapiens]
          Length = 663

 Score = 86.3 bits (212), Expect = 1e-16
 Identities = 91/320 (28%), Positives = 117/320 (36%), Gaps = 102/320 (31%)

Query: 491 PPSALGCALGESPALLRQAFLDLAEPG--------GAAGSAEAAPPPGQPPQVVANGPGS 542
           PPS    A  E+PA   +A   +A PG        G++G+  +APPP  PP      P  
Sbjct: 106 PPSQAFPAHPEAPAAAARAAALVAHPGAGSYPCGGGSSGAQPSAPPPPAPPLPPTPSPPP 165

Query: 543 GPPPP------------AGGAG------SRD--------------ALFESPPGGSGGDCS 570
            PPPP            +GG G      SRD              A+  +P GG     +
Sbjct: 166 PPPPPPPPALSGYTTTNSGGGGSSGKGHSRDFVLRRDLSATAPAAAMHGAPLGGEQRSGT 225

Query: 571 AGSTPPADSVAAAGAGAAAAG--SGPAGSRVPA------------PHHPHLLEGRKAGGG 616
                PA    +AG   +A+G  +GP GS  PA              HPH L G+   G 
Sbjct: 226 GSPQHPAPPPHSAGMFISASGTYAGPDGSGGPALFPALHDTPGAPGGHPHPLNGQMRLGL 285

Query: 617 SYHHSSAFRPVGGKDD----------------AESLAKLHG----------ASAGAPHSA 650
           +   ++A   + G+ +                A + A LHG          A+A A  +A
Sbjct: 286 AAAAAAAAAELYGRAEPPFAPRSGDAHYGAVAAAAAAALHGYGAVNLNLNLAAAAAAAAA 345

Query: 651 QTHPHHHHH-------------PHHHHHHHHPPQPPSPLLLLPPQP---------DEPGS 688
              PH  HH              H H HH H P      L    QP          +P  
Sbjct: 346 GPGPHLQHHAPPPAPPPPPAPAQHPHQHHPHLPGAAGAFLRYMRQPIKQELICKWIDPDE 405

Query: 689 ERHHPAPPPPPPPPPPPPLA 708
               P PPPPPPPPPPPP A
Sbjct: 406 LAGLPPPPPPPPPPPPPPPA 425



 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 102/352 (28%), Positives = 126/352 (35%), Gaps = 85/352 (24%)

Query: 249 AHPACHPLSSVKAAAVAA---AAAVAGGGGLLG----------PHL--LGAPPPPPPPPP 293
           AHP   P ++ +AAA+ A   A +   GGG  G          P L    +PPPPPPPPP
Sbjct: 113 AHPEA-PAAAARAAALVAHPGAGSYPCGGGSSGAQPSAPPPPAPPLPPTPSPPPPPPPPP 171

Query: 294 PLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGG-- 351
           P A L+G    +           S ++  +    S +A AA++  A   G   +G G   
Sbjct: 172 PPA-LSGYTTTNSGGGGSSGKGHS-RDFVLRRDLSATAPAAAMHGAPLGGEQRSGTGSPQ 229

Query: 352 --AGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHP- 408
             A     AG+ + A        G+ GP  +P             L   PG  G  PHP 
Sbjct: 230 HPAPPPHSAGMFISASGTYAGPDGSGGPALFP------------ALHDTPGAPGGHPHPL 277

Query: 409 -------YTFPAAAAAFSLCHKKED--------------AGAAAEALGGAGA-------G 440
                      AAAAA  L  + E               A AAA AL G GA        
Sbjct: 278 NGQMRLGLAAAAAAAAAELYGRAEPPFAPRSGDAHYGAVAAAAAAALHGYGAVNLNLNLA 337

Query: 441 GAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALG 500
            A AA  AG      P        PP     P   P   P     Q  P  P A G  L 
Sbjct: 338 AAAAAAAAG------PGPHLQHHAPP-----PAPPPPPAPAQHPHQHHPHLPGAAGAFLR 386

Query: 501 ESPALLRQAFL-DLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPPPAGGA 551
                ++Q  +    +P   AG     PPP  PP          PPPPAGGA
Sbjct: 387 YMRQPIKQELICKWIDPDELAGLPPPPPPPPPPP----------PPPPAGGA 428



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 41/116 (35%), Positives = 46/116 (39%), Gaps = 5/116 (4%)

Query: 191 HRTPDAKYTQPDAANFNSWRRHLKLTDKSPQDELVFAWEDVKAMFNGGSRKRALPQPGAH 250
           H TP A    P   N    R  L     +   EL    E   A  +G +   A+    A 
Sbjct: 264 HDTPGAPGGHPHPLN-GQMRLGLAAAAAAAAAELYGRAEPPFAPRSGDAHYGAVAAAAA- 321

Query: 251 PACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPPPLAELAGAPHAHH 306
            A H   +V      AAAA A   G  GPHL    PPP PPPPP    A  PH HH
Sbjct: 322 AALHGYGAVNLNLNLAAAAAAAAAGP-GPHLQHHAPPPAPPPPPAP--AQHPHQHH 374



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 47/176 (26%), Positives = 58/176 (32%), Gaps = 15/176 (8%)

Query: 669 PPQPPSPLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQHPHHRGLLSPGGTSCSYPS 728
           P  PP P    PP P         P P PPPPPPPPPP A   +       GG+S    S
Sbjct: 147 PSAPPPPA---PPLP---------PTPSPPPPPPPPPPPALSGYTTTNSGGGGSSGKGHS 194

Query: 729 EDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPDDDEEEDEETEVLLGDPLVGGGRFL 788
            D     D         + G  P  GE+      P           + +       G   
Sbjct: 195 RDFVLRRDLSATAPAAAMHG-APLGGEQRSGTGSPQHPAPPPHSAGMFISASGTYAGPDG 253

Query: 789 QGRGPSEKGSSRDRAPAVAGAFPLGLNSSRLLQEDGKLGDPGSDLPPPPPPPLAPQ 844
            G GP+   +  D  P   G  P  LN    L          ++L     PP AP+
Sbjct: 254 SG-GPALFPALHD-TPGAPGGHPHPLNGQMRLGLAAAAAAAAAELYGRAEPPFAPR 307



 Score = 36.2 bits (82), Expect = 0.16
 Identities = 45/193 (23%), Positives = 57/193 (29%), Gaps = 26/193 (13%)

Query: 511 LDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPPPAGGAGSRDALFESPPGGSGGDCS 570
           L L+ P  A  +   AP        +   PG+G  P  GG+         PP        
Sbjct: 102 LGLSPPSQAFPAHPEAPAAAARAAALVAHPGAGSYPCGGGSSGAQPSAPPPPAPPLPPTP 161

Query: 571 AGSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGK 630
           +   PP      A +G     SG  GS               +G G   HS  F      
Sbjct: 162 SPPPPPPPPPPPALSGYTTTNSGGGGS---------------SGKG---HSRDFVLRRDL 203

Query: 631 DDAESLAKLHGASAGAPHSAQTHPHHHHHPHHH--------HHHHHPPQPPSPLLLLPPQ 682
                 A +HGA  G    + T    H  P  H           +  P       L P  
Sbjct: 204 SATAPAAAMHGAPLGGEQRSGTGSPQHPAPPPHSAGMFISASGTYAGPDGSGGPALFPAL 263

Query: 683 PDEPGSERHHPAP 695
            D PG+   HP P
Sbjct: 264 HDTPGAPGGHPHP 276



 Score = 31.2 bits (69), Expect = 5.1
 Identities = 20/55 (36%), Positives = 24/55 (43%), Gaps = 2/55 (3%)

Query: 804 PAVAGAFPLGLNSSRLLQEDGKLGDPG--SDLPPPPPPPLAPQKASGGGSSSPGS 856
           P  AGAF   +      +   K  DP   + LPPPPPPP  P      G + P S
Sbjct: 378 PGAAGAFLRYMRQPIKQELICKWIDPDELAGLPPPPPPPPPPPPPPPAGGAKPCS 432



 Score = 30.8 bits (68), Expect = 6.6
 Identities = 16/35 (45%), Positives = 17/35 (48%), Gaps = 8/35 (22%)

Query: 829 PGSDLPPPPPPPLAPQKAS--------GGGSSSPG 855
           P +  PPPPPPP  P   S        GGGSS  G
Sbjct: 158 PPTPSPPPPPPPPPPPALSGYTTTNSGGGGSSGKG 192


>gi|40288197 GATA binding protein 6 [Homo sapiens]
          Length = 595

 Score = 85.5 bits (210), Expect = 2e-16
 Identities = 75/262 (28%), Positives = 98/262 (37%), Gaps = 40/262 (15%)

Query: 469 MFWPPRTPGGLPVPTYLQPPPQPPSALGCALGESPALLRQA---FLDLAEPGGAAGSAEA 525
           + W  R  G    P   + P +    L     + PA    A   F+  A    AA +A +
Sbjct: 127 LLWSSR--GAKLSPFAPEQPEEMYQTLAALSSQGPAAYDGAPGGFVHSAAAAAAAAAAAS 184

Query: 526 APP-----------PGQPPQVVANGPGSGPPPPAGGAGSR----DALFESPPGGSGGDCS 570
           +P            PG P  +   G GSGP   AGGAG+      A  +SPP GSGG  +
Sbjct: 185 SPVYVPTTRVGSMLPGLPYHL--QGSGSGPANHAGGAGAHPGWPQASADSPPYGSGGGAA 242

Query: 571 AGSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGK 630
            G         AAG G A + +    +R P    P +  G     G Y  + +    G  
Sbjct: 243 GGG--------AAGPGGAGSAAAHVSARFPYSPSPPMANGAAREPGGYAAAGSGGAGGVS 294

Query: 631 DDAESLAKLHGASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSER 690
               SLA + G        +   P +  + HHHHHHHH P P SP +  P  P  P    
Sbjct: 295 GGGSSLAAMGGREPQYSSLSAARPLNGTYHHHHHHHHHHPSPYSPYVGAPLTPAWPAGPF 354

Query: 691 HHP----------APPPPPPPP 702
             P          AP P P  P
Sbjct: 355 ETPVLHSLQSRAGAPLPVPRGP 376



 Score = 35.8 bits (81), Expect = 0.21
 Identities = 52/184 (28%), Positives = 66/184 (35%), Gaps = 32/184 (17%)

Query: 280 HLLGAPPPPPPPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLS-- 337
           H  GAP  P  P   +A   G   +      F D    L +AA  +    S+  A LS  
Sbjct: 86  HPFGAPHGPSAPG--VAGPGGNLSSWEDLLLFTD----LDQAATASKLLWSSRGAKLSPF 139

Query: 338 -----------VAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRS-----YP 381
                      +AA S        GA GG V      A A A A +    P +      P
Sbjct: 140 APEQPEEMYQTLAALSSQGPAAYDGAPGGFVHSAAAAAAAAAAASSPVYVPTTRVGSMLP 199

Query: 382 VIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGAGG 441
            +P   +GS  G      G G    HP  +P A+A          +G  A   G AG GG
Sbjct: 200 GLPYHLQGSGSGPANHAGGAGA---HP-GWPQASAD----SPPYGSGGGAAGGGAAGPGG 251

Query: 442 AGAA 445
           AG+A
Sbjct: 252 AGSA 255



 Score = 31.6 bits (70), Expect = 3.9
 Identities = 41/130 (31%), Positives = 54/130 (41%), Gaps = 11/130 (8%)

Query: 518 GAAGSAEAAPPPGQPPQVVANGPGSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPA 577
           GAAG A+A+     P    A  P + P P +  + S     E  PGG+  +C    TP  
Sbjct: 15  GAAG-ADASDSRAFP----AREPSTPPSPISSSSSSCSRGGERGPGGAS-NCG---TPQL 65

Query: 578 DSVAAAGAGAAAAG-SGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESL 636
           D+ AAAG  A +   S  A     APH P    G    GG+             D A + 
Sbjct: 66  DTEAAAGPPARSLLLSSYASHPFGAPHGPS-APGVAGPGGNLSSWEDLLLFTDLDQAATA 124

Query: 637 AKLHGASAGA 646
           +KL  +S GA
Sbjct: 125 SKLLWSSRGA 134



 Score = 30.4 bits (67), Expect = 8.6
 Identities = 44/173 (25%), Positives = 54/173 (31%), Gaps = 35/173 (20%)

Query: 255 PLSSVKAAAVAAAAAVAGGGGLLGP-------------HLLGAPPPPPPPPPPLAELAGA 301
           P   V +AA AAAAA A    +  P             HL G+   P       A  AG 
Sbjct: 166 PGGFVHSAAAAAAAAAAASSPVYVPTTRVGSMLPGLPYHLQGSGSGP-------ANHAGG 218

Query: 302 PHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGVG 361
             AH   P+   D               S    S   AA  G AG GG G+    V+   
Sbjct: 219 AGAHPGWPQASAD---------------SPPYGSGGGAAGGGAAGPGGAGSAAAHVSARF 263

Query: 362 VGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAA 414
             + +   A   A+ P  Y        G   G        GG  P   +  AA
Sbjct: 264 PYSPSPPMANGAAREPGGYAAAGSGGAGGVSGGGSSLAAMGGREPQYSSLSAA 316


>gi|148762982 hypothetical protein LOC387640 [Homo sapiens]
          Length = 908

 Score = 84.7 bits (208), Expect = 4e-16
 Identities = 104/358 (29%), Positives = 124/358 (34%), Gaps = 90/358 (25%)

Query: 440 GGAGAAPKAGLSGLF--WPAGRKDAFYPPFCMFWPPRTPGGLPVP-TYLQPPPQPPSALG 496
           G A A P A L  +F  +P           C   PP      P+   Y+  P  P     
Sbjct: 159 GAAAARPAAHLPQIFSKYPGSHYPEIVRSPCK--PPLNYETAPLQGNYVAFPSDPAYFRS 216

Query: 497 CALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPPPAGGAGSRDA 556
               + PA    A         AA +A AA       QV A GP       AGG GS   
Sbjct: 217 LLCSKHPAAAAAA-------AAAAAAAAAAAAAAAYYQVSAAGPQPKAAAGAGGPGSLSY 269

Query: 557 LFESPPGGSGGDC----SAGST-----PPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHL 607
             +   GG+  DC     AG+      P +    AA A AAAA +  A +        HL
Sbjct: 270 RCKRKRGGAK-DCLLAPHAGARRLLLLPRSYKAKAAAAAAAAAAAAAAAAGATCLERFHL 328

Query: 608 LEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTHPHHHHHPHHHHHHH 667
           + G             F P                    PH      HHHHH HHHHHHH
Sbjct: 329 VNG-------------FCP-------------------PPH------HHHHHHHHHHHHH 350

Query: 668 HPPQPPSPLLLLPPQPDEPGSERHHPAPPP-----PPPPPPPPPLAQHPHHRGLLSPGGT 722
           H  QPP        Q   P    HH  P P     P         + +  H    S  G+
Sbjct: 351 HRAQPPQ-------QSHHP---PHHHRPQPHLGSFPESCSSDSESSSYSDHAANDSDFGS 400

Query: 723 SCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPDDD------EEEDEETE 774
           S S  S   S +E++EE E+E         E EEEEEG     D      EEED  TE
Sbjct: 401 SLSSSSNSVSSEEEEEEGEEE---------EEEEEEEGGSGASDSSEVSSEEEDSSTE 449



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 21/82 (25%), Positives = 40/82 (48%)

Query: 48  GIPIVSLVIDGQERLCLAQISNTLLKNFSYNEIHNRRVALGITCVQCTPVQLEILRRAGA 107
           G+ +  L+I G++   L+Q+   LLKN     +H R   L +    C   +L  L+   +
Sbjct: 13  GVRLGYLIIKGKQMFALSQVFTDLLKNIPRTTVHKRMDHLKVKKHHCDLEELRKLKAINS 72

Query: 108 MPISSRRCGMITKREAERLCKS 129
           +   + +C +I++ + E L  S
Sbjct: 73  IAFHAAKCTLISREDVEALYTS 94



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 42/121 (34%), Positives = 47/121 (38%), Gaps = 30/121 (24%)

Query: 325 AAASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIP 384
           AAA+ +AAAA+ + AAA+  A      A          G    A AGAG  G  SY    
Sbjct: 224 AAAAAAAAAAAAAAAAAAAAAYYQVSAA----------GPQPKAAAGAGGPGSLSY---- 269

Query: 385 VPSKGSFGGVLQKF--PGCGG----LFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAG 438
              K   GG       P  G     L P  Y   AAAAA         A AAA A   AG
Sbjct: 270 -RCKRKRGGAKDCLLAPHAGARRLLLLPRSYKAKAAAAA---------AAAAAAAAAAAG 319

Query: 439 A 439
           A
Sbjct: 320 A 320


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 82.8 bits (203), Expect = 1e-15
 Identities = 179/663 (26%), Positives = 210/663 (31%), Gaps = 101/663 (15%)

Query: 262  AAVAAAAAVAGGGGLLGPHLLGAPPPP--------PPPPPPLAELAGA-----PHAHHKR 308
            A +  A  + G  G  GP     PP P        PP PP     AG      P      
Sbjct: 532  AGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGE 591

Query: 309  PRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGA 368
            P    +         V  A     A +      +G AG  G     G     G+   AG 
Sbjct: 592  PGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGP 651

Query: 369  GAGAGAKGPRSYPV---IPVPSKGSFGGVLQKFPGCGGLF--PHPYTFPAAAAAFSLCHK 423
               AG  G +  P     P PS G+ G   + FPG  G+   P P     A  A      
Sbjct: 652  PGEAGKPGEQGVPGDLGAPGPS-GARGE--RGFPGERGVQGPPGPAGPRGANGAPGNDGA 708

Query: 424  KEDAGAAAEALGGAGAGGAGAAP-KAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVP 482
            K DAGA   A G  GA G    P + G +GL  P G +    P         +PG   V 
Sbjct: 709  KGDAGAPG-APGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGA----DGSPGKDGVR 763

Query: 483  TYLQP--PPQPPSALGCALGES-------PALLRQAFLDLAEPGGAAGSAEAAPPPGQPP 533
                P  PP P  A G   GES       P   R A  D  EPG   G A  A PPG   
Sbjct: 764  GLTGPIGPPGPAGAPGDK-GESGPSGPAGPTGARGAPGDRGEPG-PPGPAGFAGPPGADG 821

Query: 534  QVVANG-PG-------SGPPPPAGGAGSRDALFE-SPPGGSGGDCSAGSTPPADSVAAAG 584
            Q  A G PG       +GPP PAG AG    +     PG  G   SAG   P  +    G
Sbjct: 822  QPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAG---PPGATGFPG 878

Query: 585  AGAAAAGSGPAGSR-VPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGAS 643
            A       GP+G+   P P  P   EG K   G    +     VG         +     
Sbjct: 879  AAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPG 938

Query: 644  AGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLL-LPPQPDEPGSERHHPAPPPPPPPP 702
            A  P  A   P              P Q        LP    EPG +    A     PP 
Sbjct: 939  ADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPG 998

Query: 703  PPPPLAQHPHHRGLLSPGGTSCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRD 762
            P  P        GL  P G S                        G +   G E   GRD
Sbjct: 999  PMGP-------PGLAGPPGES------------------------GREGAPGAEGSPGRD 1027

Query: 763  PDDDEEEDEETEVLLGDPLVGGGRFLQGR-GPSEKGSSRDRAPAVAGAFPLGLNSSRLLQ 821
                 + D       G P   G     G  GP+ K   R        A P+G   +R   
Sbjct: 1028 GSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPA 1087

Query: 822  ----------EDGKLGDPG-------SDLPPPPPPPLAPQKASGGGSSSPGSPVHHPSLE 864
                      E G+ GD G       S L  PP PP +P +    G+S P  P   P   
Sbjct: 1088 GPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSA 1147

Query: 865  EQP 867
              P
Sbjct: 1148 GAP 1150



 Score = 77.0 bits (188), Expect = 8e-14
 Identities = 172/681 (25%), Positives = 205/681 (30%), Gaps = 119/681 (17%)

Query: 247  PGAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPPPLAELAGAPHAHH 306
            PGA        +  A  +A A    G  G  GP   G PP P          +G P A  
Sbjct: 388  PGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGN-------SGEPGA-- 438

Query: 307  KRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGA 366
              P    D  +  E   V        A       A G  G  G     G   G G     
Sbjct: 439  --PGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFP 496

Query: 367  GAGAGAGAKGPRSYPVIPVPS--KGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSLCHKK 424
            GA   AG KGP      P P+  KGS G   +  PG  GL P       +  +     K 
Sbjct: 497  GADGVAGPKGPAGERGSPGPAGPKGSPGEAGR--PGEAGL-PGAKGLTGSPGSPGPDGKT 553

Query: 425  EDAGAAAEALGGAGAGGAGAAPKAGLSGLFWP---------AGRKDAFYPPFCMFWPPRT 475
               G A +       G  GA  +AG+ G   P         AG +    PP  +      
Sbjct: 554  GPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAV-----G 608

Query: 476  PGGLPVPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQV 535
            P G       Q PP P    G   GE        F  L  P G  G A      G P  +
Sbjct: 609  PAGKDGEAGAQGPPGPAGPAG-ERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDL 667

Query: 536  VANGPG--------------SGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVA 581
             A GP                GPP PAG  G+  A     PG  G    AG+     S  
Sbjct: 668  GAPGPSGARGERGFPGERGVQGPPGPAGPRGANGA-----PGNDGAKGDAGAPGAPGSQG 722

Query: 582  AAGAGAAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHG 641
            A G        G AG  +P P       G K   GS           GKD    L    G
Sbjct: 723  APGLQGMPGERGAAG--LPGPKGDRGDAGPKGADGS----------PGKDGVRGLTGPIG 770

Query: 642  --ASAGAP----HSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPP-----------QPD 684
                AGAP     S  + P               P PP P     P           +P 
Sbjct: 771  PPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPG 830

Query: 685  EPGSERHHPAPPPPPPPPPPPPLAQ-----HPHHRGLLSPGGTSCSYPS-------EDSS 732
            + G++     P P  P  PP P+           RG   P G +  +P           S
Sbjct: 831  DAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGAT-GFPGAAGRVGPPGPS 889

Query: 733  EDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPDDDEEEDEETEVLLGDPLVGGGRFLQGRG 792
             +            EG K P GE    GR  +            +G P   G        
Sbjct: 890  GNAGPPGPPGPAGKEGGKGPRGETGPAGRPGE------------VGPPGPPG-------P 930

Query: 793  PSEKGSSRDRAPAVAGAF--PLGLNSSR----LLQEDGKLGDPGSDLPPPPPPPLAPQKA 846
              EKGS     PA A     P G+   R    L  + G+ G PG  LP P   P     +
Sbjct: 931  AGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPG--LPGPSGEPGKQGPS 988

Query: 847  SGGGSSSPGSPVHHPSLEEQP 867
               G   P  P+  P L   P
Sbjct: 989  GASGERGPPGPMGPPGLAGPP 1009



 Score = 63.5 bits (153), Expect = 9e-10
 Identities = 165/650 (25%), Positives = 196/650 (30%), Gaps = 95/650 (14%)

Query: 268 AAVAGGGGLLGPHLLGAPPPPPPPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAA 327
           A   G  G+ G   L  PP PP PP P     G   A      +D+              
Sbjct: 126 AGPPGRDGIPGQPGLPGPPGPPGPPGPPG--LGGNFAPQLSYGYDE-------------- 169

Query: 328 SLSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIP-VP 386
               +   +SV    G +G  G     G     G     G     GA GP      P  P
Sbjct: 170 ---KSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPP 226

Query: 387 SKGSFGGVLQKFPGCGGLFPHP-----YTFPAAAA--------AFS-LCHKKEDAGAAAE 432
            K    G   K PG  G    P        P  A          FS L   K DAG A  
Sbjct: 227 GKNGDDGEAGK-PGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGP 285

Query: 433 ALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRT-PGGLPVPTYLQPPPQP 491
                  G  GA  + G  GL    GR  A  P         T   G P PT    PP  
Sbjct: 286 KGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGF 345

Query: 492 PSALGCALGESPALLR-----QAFLDLAEPGGAAGSAEAAPPP---GQPPQVVANG-PG- 541
           P A+G      P   R     Q       P G AG+A  A  P   GQP    ANG PG 
Sbjct: 346 PGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGI 405

Query: 542 ------------SGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAA 589
                       SGP  P G  G +    E    GS GD  A   P    V   G    A
Sbjct: 406 AGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEP--GPVGVQGPPGPA 463

Query: 590 AGSGPAGSR-VPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPH 648
              G  G+R  P P       G + G GS     A    G K  A        A      
Sbjct: 464 GEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSP 523

Query: 649 SAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLA 708
                P     P        P  P       PP    P  +   P PP PP       + 
Sbjct: 524 GEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPP---GPAGQDGRPGPPGPPGARGQAGVM 580

Query: 709 QHPHHRGLLSPGGTSCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPDDDEE 768
             P  +G     G +                ++ E   +G   P G   E G      E+
Sbjct: 581 GFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERG------EQ 634

Query: 769 EDEETEVLLGDPLVGGGRFLQGRGPSEKGSSRD-RAPAVAGAFPLGLNSSRLLQEDGKLG 827
               +    G P   G     G+ P E+G   D  AP  +GA              G+ G
Sbjct: 635 GPAGSPGFQGLPGPAGPPGEAGK-PGEQGVPGDLGAPGPSGA-------------RGERG 680

Query: 828 DPGSDLPPPPPPPLAPQKASG--------GGSSSPGSPVHH--PSLEEQP 867
            PG      PP P  P+ A+G        G + +PG+P     P L+  P
Sbjct: 681 FPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMP 730



 Score = 58.5 bits (140), Expect = 3e-08
 Identities = 150/624 (24%), Positives = 186/624 (29%), Gaps = 143/624 (22%)

Query: 267 AAAVAGGGGLLGPHLLGAPPPPPPP--PPPLAELAGAP-HAHHKRPRFDDDDDSLQEAAV 323
           A   AG  G  G      PP P  P  PP      GA   A  + PR  +    ++    
Sbjct: 315 APGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVR---- 370

Query: 324 VAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPR--SYP 381
                          A A+G AG  G     G     G    AGA    GA+GP     P
Sbjct: 371 -------GEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGP 423

Query: 382 VIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSLCHKKEDAGAAAE--------A 433
             P   KG+ G      PG  G                    K D GA  E         
Sbjct: 424 GGPPGPKGNSGE-----PGAPG-------------------SKGDTGAKGEPGPVGVQGP 459

Query: 434 LGGAG-AGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPG--GLPVPTYLQPPPQ 490
            G AG  G  GA  + G +GL  P G +               PG  G P    +  P  
Sbjct: 460 PGPAGEEGKRGARGEPGPTGLPGPPGERGG-------------PGSRGFPGADGVAGPKG 506

Query: 491 PPSALGCALGESPALLRQAFLDLAEPG--------GAAGSAEAAPPPGQ--PPQVVANGP 540
           P    G      PA  + +  +   PG        G  GS  +  P G+  PP       
Sbjct: 507 PAGERG---SPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDG 563

Query: 541 GSGPPPPAGGAGSRDAL-FESPPGGSGGDCSAGS---TPPADSVAAAGAGAAAAGSGPAG 596
             GPP P G  G    + F  P G +G    AG      P  +V  AG    A   GP G
Sbjct: 564 RPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPG 623

Query: 597 SRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTHPHH 656
              PA        G +   G    S  F+ + G              AG P  A      
Sbjct: 624 PAGPAGE-----RGEQGPAG----SPGFQGLPG-------------PAGPPGEA------ 655

Query: 657 HHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAP---PPPPPPPPPPPLAQHPHH 713
                       P +   P  L  P P     ER  P       PP P  P      P +
Sbjct: 656 ----------GKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGN 705

Query: 714 RGLLSPGGTSCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPDDDEEEDEET 773
            G     G   +  S+ +   +    E     + G K   G+   +G D    ++     
Sbjct: 706 DGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGL 765

Query: 774 EVLLGDPLVGGGRFLQGRGPSEKGSSRDRAPAVAGAFPLGLNSSRLLQEDGKLGDPGSDL 833
              +G P   G        P +KG S    PA       G   +R     G  GD G   
Sbjct: 766 TGPIGPPGPAG-------APGDKGESGPSGPA-------GPTGAR-----GAPGDRGEPG 806

Query: 834 PPPPPPPLAPQKASG--GGSSSPG 855
           PP P     P  A G  G    PG
Sbjct: 807 PPGPAGFAGPPGADGQPGAKGEPG 830



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 125/518 (24%), Positives = 157/518 (30%), Gaps = 119/518 (22%)

Query: 271  AGGGGLLGPHLLGAPPPPPPPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLS 330
            AG  G  GP     P  P  PP P+  + GAP A   R            A    A    
Sbjct: 832  AGAKGDAGPP---GPAGPAGPPGPIGNV-GAPGAKGARG----------SAGPPGATGFP 877

Query: 331  AAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGS 390
             AA  +     SG AG  G     G   G G     G     G  GP   P  P   KGS
Sbjct: 878  GAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPG-PAGEKGS 936

Query: 391  FGGVLQKFPGCGGLFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGAGGAGAAPKAGL 450
                    PG  G        PA A                        G  G A + G+
Sbjct: 937  --------PGADG--------PAGAPGTP--------------------GPQGIAGQRGV 960

Query: 451  SGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGESPALLRQAF 510
             GL  P  R +  +P            GLP P+  +P  Q PS      G          
Sbjct: 961  VGL--PGQRGERGFP------------GLPGPSG-EPGKQGPSGASGERG---------- 995

Query: 511  LDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPPPAGGAGSRDALFES----PPGGSG 566
                 P G  G    A PPG+  +  A G   G P   G  G++    E+    PPG  G
Sbjct: 996  -----PPGPMGPPGLAGPPGESGREGAPG-AEGSPGRDGSPGAKGDRGETGPAGPPGAPG 1049

Query: 567  GDCSAGSTPPADSV---AAAGAGAAAAGSGPAGSRVPA----PHHPHLLEGRKAGGGSYH 619
               + G   PA         G    A   GP G+R PA    P       G +   G   
Sbjct: 1050 APGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKG 1109

Query: 620  HSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLL 679
            H       G      S  +   + A  P   +  P     P     +  P        + 
Sbjct: 1110 HRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGP------IG 1163

Query: 680  PPQPDEPGSERHHPAPPPPPPPPPPPP----------LAQHPHHRGLLSPGGTSCSYPSE 729
            PP P     +     PP PP PP PP           L Q P  +     GG    Y ++
Sbjct: 1164 PPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKA--HDGGR--YYRAD 1219

Query: 730  DSSEDEDDEEEEQEV------DVEGHKPPEGEEEEEGR 761
            D++   D + E           +E  + PEG  +   R
Sbjct: 1220 DANVVRDRDLEVDTTLKSLSQQIENIRSPEGSRKNPAR 1257



 Score = 30.8 bits (68), Expect = 6.6
 Identities = 86/381 (22%), Positives = 115/381 (30%), Gaps = 65/381 (17%)

Query: 518 GAAGSAEAAPPPGQ---PPQVVANGPGSGPPPPAGGAGSRDALFESPPGGSGGDCSAGST 574
           G  G    A PPG+   P Q    GP   P PP              P G GG+ +   +
Sbjct: 118 GPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPG-------------PPGLGGNFAPQLS 164

Query: 575 PPADSVAAAGAGAAAAGSGPAGSR-VPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGK--- 630
              D  +  G  +     GP+G R +P P      +G +   G      A  P+G +   
Sbjct: 165 YGYDEKSTGGI-SVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPP 223

Query: 631 -------DDAESLAKLHGASAG--APHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPP 681
                  DD E+         G   P  A+  P     P    H        +     P 
Sbjct: 224 GPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPA 283

Query: 682 QP-DEPGSERHHPAPPPPPP---------PPPPPP-----------LAQHPHHRGLLSPG 720
            P  EPGS   + AP    P         P  P P            A  P   G   P 
Sbjct: 284 GPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPP 343

Query: 721 GTSCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPDDDEEEDEETEVLLGDP 780
           G   +  ++  +  +     E    V G   P G     G   +   +     +   G P
Sbjct: 344 GFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAP 403

Query: 781 -LVGGGRFLQGRGPSEKGSSRDRAPAVAGAFPLGLNSSRLLQEDGKLGDPGSDLPPPP-- 837
            + G   F   RGPS         P   G  P    +S      G  GD G+   P P  
Sbjct: 404 GIAGAPGFPGARGPS--------GPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVG 455

Query: 838 ---PPPLAPQKASGGGSSSPG 855
              PP  A ++   G    PG
Sbjct: 456 VQGPPGPAGEEGKRGARGEPG 476


>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
            sapiens]
          Length = 1130

 Score = 81.3 bits (199), Expect = 4e-15
 Identities = 120/448 (26%), Positives = 156/448 (34%), Gaps = 84/448 (18%)

Query: 485  LQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAA-----PPPGQPPQVVANG 539
            L P P+ P  L CAL       R+  L+++     A    AA      PP QP       
Sbjct: 588  LAPSPRCPPPLACALQAFSLGQREDSLEVSSFCSEALVTCAALTHPRVPPLQPMGPTCPT 647

Query: 540  PGSGPPPPAGGAGSRDALFESPPGGSGGDC-SAGSTPPADSVAAAGAGAAAAGSGPAGSR 598
            P   PPP A       + F +PP    G   S GS P A  + +AG   +A   GP  S 
Sbjct: 648  PAPVPPPEA------PSPFRAPPFHPPGPMPSVGSMPSAGPMPSAGPMPSA---GPVPSA 698

Query: 599  VPAP----HH------------PHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGA 642
             P P    +H            P LL G +      +      P G         +  G 
Sbjct: 699  RPGPPTTANHLGLSVPGLVSVPPRLLPGPENHRAGSNEDPILAPSGTPPPTIPPDETFGG 758

Query: 643  SAGAPHSAQTHPHHHHHPHHHHHHHH----------------PPQPPS-----------P 675
                P  A  H                               PP PPS           P
Sbjct: 759  R--VPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGP 816

Query: 676  LLLLPPQP--DEPGSERHHPAPPPPPPPPPPP---PLAQHPHH---RGLLSPGGTSCSYP 727
                PP P  +EP      P P PPPPPPPPP   P+   P      G  +PGG      
Sbjct: 817  PTASPPVPAKEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEG--TPGGGGPPAL 874

Query: 728  SED-------SSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPDDDEEEDEETEVLLGDP 780
             ED       SS++E++EEEE+E + E  +  E + EEE  D ++  EE+EE E    + 
Sbjct: 875  EEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEE 934

Query: 781  LVGGGRFLQGRGPSEKGSSRDRAPAVAGAFPLGLNSSRLLQEDGKLGDPGSDLPPPPPPP 840
                   L+     E     +    V     L   ++    E+G    P   LPP  PPP
Sbjct: 935  FEEEEGELEEEEEEEDEEEEEELEEVE---DLEFGTAGGEVEEG--APPPPTLPPALPPP 989

Query: 841  LAPQKASGGGSSSPG--SPVHHPSLEEQ 866
             +P K        PG    V  P  EE+
Sbjct: 990  ESPPKVQPEPEPEPGLLLEVEEPGTEEE 1017



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 69/309 (22%), Positives = 112/309 (36%), Gaps = 45/309 (14%)

Query: 668 HPPQPPSPLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQHPHHRGLLSPGGTSCSYP 727
           HPP P   +  +P     P +     A P P   P PP  A   +H GL  PG  S    
Sbjct: 666 HPPGPMPSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTA---NHLGLSVPGLVSVPPR 722

Query: 728 SEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEE---GRDPDD-----DEEEDEETEVLL-- 777
                E+      E  +      PP     +E   GR P       D+EE  + E+ L  
Sbjct: 723 LLPGPENHRAGSNEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLES 782

Query: 778 --GDPLVGGGRFLQGRGPSEKGSSRDRAPAVAGAFPLGLNSSRLLQEDGKLGDPGSDLPP 835
              D +V     L    P     +     A  G  P         +E  +L      LPP
Sbjct: 783 DSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGP-PTASPPVPAKEEPEELPAAPGPLPP 841

Query: 836 PPPPP--------LAPQKASGGGSSSPGSPVHHPSLEE--------QPSYKDSQKTKENN 879
           PPPPP        L P +    G+   G P   P+LEE            ++ ++ +E  
Sbjct: 842 PPPPPPPVPGPVTLPPPQLVPEGTPGGGGP---PALEEDLTVININSSDEEEEEEEEEEE 898

Query: 880 QVIVSTKDDNSFSDKNKEHSFFITDSDASGGDF---WRERSGEHTQETNSPHSLKKDVEN 936
           +     +++  F ++ ++   +  + +    +F   + E  GE  +E       +++ + 
Sbjct: 899 EEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEEEGELEEE-------EEEEDE 951

Query: 937 MGKEELQKV 945
             +EEL++V
Sbjct: 952 EEEEELEEV 960



 Score = 36.2 bits (82), Expect = 0.16
 Identities = 34/121 (28%), Positives = 49/121 (40%), Gaps = 17/121 (14%)

Query: 670  PQP-PSPLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQHPHHRGLLSPGGTSCSYPS 728
            P+P P P LLL  + +EPG+E    A   P   P   P        G     G     P 
Sbjct: 997  PEPEPEPGLLL--EVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGP----PP 1050

Query: 729  EDSSEDEDD------EEEEQEVDVEGHKPPEGEEEEEGRDPDD----DEEEDEETEVLLG 778
            ++  E+E        EEE ++   +   PPE   EEE     +     E+E ++T  +L 
Sbjct: 1051 QELVEEEPSAPPTLLEEETEDGSDKVQPPPETPAEEEMETETEAEALQEKEQDDTAAMLA 1110

Query: 779  D 779
            D
Sbjct: 1111 D 1111



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 30/101 (29%), Positives = 37/101 (36%), Gaps = 14/101 (13%)

Query: 680  PPQPDEPGSERHHPAPPPP-------PPPPPPPPLAQHPHHRGLLSP-GGTSCSYPSEDS 731
            PP P  P      PA PPP       P P P P L       G     G  +    + ++
Sbjct: 977  PPPPTLP------PALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEA 1030

Query: 732  SEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPDDDEEEDEE 772
               + + E E E    G  P E  EEE    P   EEE E+
Sbjct: 1031 LPSQGEVEREGESPAAGPPPQELVEEEPSAPPTLLEEETED 1071



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 30/95 (31%), Positives = 35/95 (36%), Gaps = 20/95 (21%)

Query: 472 PPRTPGGLPVPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQ 531
           PP  P   P P+   PPP  P+    A    PA          EP     +    PPP  
Sbjct: 796 PPLPP---PPPSGATPPPIAPTGPPTASPPVPAK--------EEPEELPAAPGPLPPPPP 844

Query: 532 PPQVVANGPGSGPPPPAGGAGSRDALFESPPGGSG 566
           PP  V  GP + PPP          + E  PGG G
Sbjct: 845 PPPPVP-GPVTLPPP--------QLVPEGTPGGGG 870



 Score = 30.4 bits (67), Expect = 8.6
 Identities = 11/17 (64%), Positives = 12/17 (70%)

Query: 279 PHLLGAPPPPPPPPPPL 295
           P   G  PPPPPPPPP+
Sbjct: 833 PAAPGPLPPPPPPPPPV 849


>gi|5453936 POU class 3 homeobox 3 [Homo sapiens]
          Length = 500

 Score = 79.7 bits (195), Expect = 1e-14
 Identities = 117/421 (27%), Positives = 140/421 (33%), Gaps = 134/421 (31%)

Query: 329 LSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGA---GAGAKGPRSYPVIPV 385
           L+A +   S AA +GG G GGGG GGG   G G G   G+ A   GA    P S  ++  
Sbjct: 16  LAAGSIVHSDAAGAGGGGGGGGGGGGGGAGGGGGGMQPGSAAVTSGAYRGDPSSVKMV-- 73

Query: 386 PSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGAGGAGAA 445
                  G +    G G +  H + +  A     L H    A AAA A   A +  +G+A
Sbjct: 74  -QSDFMQGAMAASNG-GHMLSHAHQWVTA-----LPHAAAAAAAAAAAAVEASSPWSGSA 126

Query: 446 PKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGESPAL 505
              G++G                   P + P         QPPP PP        + P +
Sbjct: 127 --VGMAGS------------------PQQPP---------QPPPPPP--------QGPDV 149

Query: 506 LRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPPPAGGAGSRDALFESPPGGS 565
              A  D    G A       PP   PP          PPPP  G           PGG 
Sbjct: 150 KGGAGRDDLHAGTAL--HHRGPPHLGPP----------PPPPHQG----------HPGGW 187

Query: 566 GGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFR 625
           G   +A       + AAA A AAA     AG + P P    LL  +  G       SA  
Sbjct: 188 GAAAAA-------AAAAAAAAAAAHLPSMAGGQQPPPQ--SLLYSQPGGFTVNGMLSAPP 238

Query: 626 PVGGKDDAESLAKLHGASAGAPHSAQTHP----------HHHHHPHHHHHHHHPPQPPSP 675
             GG           G  AG    +  HP            HHH HHHH H HPP P   
Sbjct: 239 GPGG----------GGGGAGGGAQSLVHPGLVRGDTPELAEHHHHHHHHAHPHPPHP--- 285

Query: 676 LLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQHPHHRGLLSPGGTSCSYPSEDSSEDE 735
                          HH   P              PHH G    GG      S D   DE
Sbjct: 286 ---------------HHAQGP--------------PHHGG--GGGGAGPGLNSHDPHSDE 314

Query: 736 D 736
           D
Sbjct: 315 D 315



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 49/154 (31%), Positives = 62/154 (40%), Gaps = 36/154 (23%)

Query: 255 PLSSVKAAAVAAAAAVAGG---GGLLGPHLLGAP--PPPPPPPPP--------------- 294
           P ++  AAA AAAA  A     G  +G  + G+P  PP PPPPPP               
Sbjct: 102 PHAAAAAAAAAAAAVEASSPWSGSAVG--MAGSPQQPPQPPPPPPQGPDVKGGAGRDDLH 159

Query: 295 ---LAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGG------- 344
                   G PH     P           AA  AAA+ +AAAA+  + + +GG       
Sbjct: 160 AGTALHHRGPPHLGPPPPPPHQGHPGGWGAAAAAAAAAAAAAAAAHLPSMAGGQQPPPQS 219

Query: 345 ---AGTGGGGAGGGCVAGVGVGAGAGAGAGAGAK 375
              +  GG    G   A  G G G G GAG GA+
Sbjct: 220 LLYSQPGGFTVNGMLSAPPGPG-GGGGGAGGGAQ 252



 Score = 33.5 bits (75), Expect = 1.0
 Identities = 20/60 (33%), Positives = 24/60 (40%), Gaps = 2/60 (3%)

Query: 803 APAVAGAFPLGLNSSRLLQEDGKLGDPGSDLPPPPPPPLAPQKASGGGSSS--PGSPVHH 860
           A A A A  +  +S       G  G P     PPPPPP  P    G G      G+ +HH
Sbjct: 107 AAAAAAAAAVEASSPWSGSAVGMAGSPQQPPQPPPPPPQGPDVKGGAGRDDLHAGTALHH 166


>gi|61966923 forkhead box B2 [Homo sapiens]
          Length = 432

 Score = 79.3 bits (194), Expect = 2e-14
 Identities = 36/79 (45%), Positives = 39/79 (49%), Gaps = 15/79 (18%)

Query: 642 ASAGAPHSAQTHPHHHHHPHHHHHHH---------HPPQPPSPLLLLPPQPDEPGSERHH 692
           ++ GA      HPHHHHHPHHHHHHH         HPPQPP      PP P  P    H+
Sbjct: 126 SAPGAGPGGHLHPHHHHHPHHHHHHHAAAHHHHHHHPPQPP------PPPPPPPPHMVHY 179

Query: 693 PAPPPPPPPPPPPPLAQHP 711
               PP  P PPP L   P
Sbjct: 180 FHQQPPTAPQPPPHLPSQP 198



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 72/264 (27%), Positives = 90/264 (34%), Gaps = 61/264 (23%)

Query: 285 PPPPPPPPPP--------LAELAGAPHAH-----------HKRPRFDDDDDSLQEAAVVA 325
           PPPPPPPPPP            A  P  H             +P+       +QEAA VA
Sbjct: 165 PPPPPPPPPPHMVHYFHQQPPTAPQPPPHLPSQPPQQPPQQSQPQQPSHPGKMQEAAAVA 224

Query: 326 AASLSAAAASL-SVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAG------AGAGAKGPR 378
           AA+ +AAAA++ SV   S     G G A     A     +G           G   KG  
Sbjct: 225 AAAAAAAAAAVGSVGRLSQFPPYGLGSAAAAAAAAAASTSGFKHPFAIENIIGRDYKGVL 284

Query: 379 SYPVIPV---------PSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSLCHKKEDAGA 429
               +P+         P  G  G V+        ++PH     + AAA +       A A
Sbjct: 285 QAGGLPLASVMHHLGYPVPGQLGNVV------SSVWPHVGVMDSVAAAAA-------AAA 331

Query: 430 AAEALGGAGAGGAGAAPKA-------GLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVP 482
           AA    G   G  G   K+        L  +  P     A  PP     P     GL VP
Sbjct: 332 AAGVPVGPEYGAFGVPVKSLCHSASQSLPAMPVPIKPTPAL-PPVSALQP-----GLTVP 385

Query: 483 TYLQPPPQPPSALGCALGESPALL 506
              Q PP P +    A     A L
Sbjct: 386 AASQQPPAPSTVCSAAAASPVASL 409



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 53/241 (21%), Positives = 74/241 (30%), Gaps = 65/241 (26%)

Query: 386 PSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGAGGAGAA 445
           P KGSF  +    P CG +F +           S   +++             AG   +A
Sbjct: 81  PGKGSFWAL---HPDCGDMFENG----------SFLRRRKRFKVLRADHTHLHAGSTKSA 127

Query: 446 PKAGLSGLFWP---------------AGRKDAFYPPFCMFWPPRTPGGLPVPTYLQPP-- 488
           P AG  G   P               A      +PP     PP  P  +    + QPP  
Sbjct: 128 PGAGPGGHLHPHHHHHPHHHHHHHAAAHHHHHHHPPQPPPPPPPPPPHMVHYFHQQPPTA 187

Query: 489 PQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPPPA 548
           PQPP  L                              + PP QPPQ       S P  P+
Sbjct: 188 PQPPPHL-----------------------------PSQPPQQPPQQ------SQPQQPS 212

Query: 549 GGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLL 608
                ++A   +    +    + GS          G G+AAA +  A +      HP  +
Sbjct: 213 HPGKMQEAAAVAAAAAAAAAAAVGSVGRLSQFPPYGLGSAAAAAAAAAASTSGFKHPFAI 272

Query: 609 E 609
           E
Sbjct: 273 E 273



 Score = 33.1 bits (74), Expect = 1.3
 Identities = 15/43 (34%), Positives = 20/43 (46%)

Query: 834 PPPPPPPLAPQKASGGGSSSPGSPVHHPSLEEQPSYKDSQKTK 876
           PPPPPPP  P          P +P   P L  QP  +  Q+++
Sbjct: 165 PPPPPPPPPPHMVHYFHQQPPTAPQPPPHLPSQPPQQPPQQSQ 207


>gi|32307177 forkhead box G1 [Homo sapiens]
          Length = 489

 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 56/159 (35%), Positives = 67/159 (42%), Gaps = 51/159 (32%)

Query: 640 HGASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPP- 698
           H AS G  H    HP HHHH  HHHHHHHPP P        PQP  P  ++  P PPPP 
Sbjct: 33  HHASHG--HHNSHHPQHHHH--HHHHHHHPPPP-------APQPPPPPQQQQPPPPPPPA 81

Query: 699 -----------------------PPPPPPPPLAQHPHHR-----GLLSPGGTSCSYPSED 730
                                  PPPPPPPP A     +     G   PGG     P E 
Sbjct: 82  PQPPQTRGAPAADDDKGPQQLLLPPPPPPPPAAALDGAKADGLGGKGEPGGG----PGEL 137

Query: 731 SSEDEDDEE-------EEQEVDVEGHKPPEGEEEEEGRD 762
           +    D++E       EE++   EG K  EG +E E ++
Sbjct: 138 APVGPDEKEKGAGAGGEEKKGAGEGGKDGEGGKEGEKKN 176



 Score = 48.1 bits (113), Expect = 4e-05
 Identities = 41/105 (39%), Positives = 45/105 (42%), Gaps = 15/105 (14%)

Query: 284 APPPPPPP----PPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVA 339
           AP PPPPP    PPP    A  P      P  DDD    Q   ++        AA+L  A
Sbjct: 62  APQPPPPPQQQQPPPPPPPAPQPPQTRGAPAADDDKGPQQ--LLLPPPPPPPPAAALDGA 119

Query: 340 AASGGAGTGGGGAGGGCVAGVG-----VGAGAGA----GAGAGAK 375
            A G  G G  G G G +A VG      GAGAG     GAG G K
Sbjct: 120 KADGLGGKGEPGGGPGELAPVGPDEKEKGAGAGGEEKKGAGEGGK 164



 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 37/119 (31%), Positives = 42/119 (35%), Gaps = 28/119 (23%)

Query: 285 PPPPPPPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGG 344
           PPPPPPP P   +  GAP A         DDD   +  ++        AA+L  A A G 
Sbjct: 74  PPPPPPPAPQPPQTRGAPAA---------DDDKGPQQLLLPPPPPPPPAAALDGAKADGL 124

Query: 345 AGTG-------------------GGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIP 384
            G G                   G GAGG    G G G   G G   G K    Y   P
Sbjct: 125 GGKGEPGGGPGELAPVGPDEKEKGAGAGGEEKKGAGEGGKDGEGGKEGEKKNGKYEKPP 183



 Score = 38.5 bits (88), Expect = 0.032
 Identities = 38/128 (29%), Positives = 47/128 (36%), Gaps = 26/128 (20%)

Query: 472 PPRTPGGLPVPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQ 531
           PP  P   P P   QPPP PP A                    +P    G A AA     
Sbjct: 59  PPPAPQPPPPPQQQQPPPPPPPA-------------------PQPPQTRG-APAADDDKG 98

Query: 532 PPQVVANGPGSGPPPPAG---GAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAA 588
           P Q++   P   PPPPA    GA +     +  PGG  G+ +       +  A AG G  
Sbjct: 99  PQQLLL--PPPPPPPPAAALDGAKADGLGGKGEPGGGPGELAPVGPDEKEKGAGAG-GEE 155

Query: 589 AAGSGPAG 596
             G+G  G
Sbjct: 156 KKGAGEGG 163


>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
           [Homo sapiens]
          Length = 2231

 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 141/560 (25%), Positives = 181/560 (32%), Gaps = 127/560 (22%)

Query: 342 SGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFPGC 401
           +GG G GGGG GGG   G G G GAGAG GAGA    +       + G  GG      G 
Sbjct: 248 AGGGGGGGGGGGGGS-GGGGGGGGAGAG-GAGAGAVAAAAAAAAAAAGGGGG-----GGY 300

Query: 402 GGLFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGAGGAGAAPKAGLSGLF------- 454
           GG         ++A    L   ++  G      GG GA     A     +G F       
Sbjct: 301 GG---------SSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQN 351

Query: 455 -WPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQP--PPQPPSALGCALGESPALLRQAFL 511
             P+G             P     G   P Y  P  PP PPS              Q   
Sbjct: 352 QHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPS--------------QPQS 397

Query: 512 DLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPPPAGGAGSRDALFESPPGGSGGDCSA 571
             A  G AAG  +AA   G    + A    + P   A    S  A+    PG + G  S 
Sbjct: 398 QAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGR-SQ 456

Query: 572 GSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFR-PVGGK 630
           GS  P D +          GS P      +  +P         GGSY      R P+G +
Sbjct: 457 GS--PMDPMVMKRPQLYGMGSNPHSQPQQSSPYP---------GGSYGPPGPQRYPIGIQ 505

Query: 631 DDAESLAKLHGASAGAPHSAQTHPHHHH--------HPHHHHHHHHPPQPPSPLLLLPPQ 682
                  +  GA AG  +  Q  P  +               ++   PQPP     LPPQ
Sbjct: 506 ------GRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPH----LPPQ 555

Query: 683 PD---EPGSERHHPAPPPPPP---PPPPPPLAQ-HPHHRGL-LSPGGTSCSYPSEDSSED 734
                    +R+ P              PPLA   P+H  L L       S P    S D
Sbjct: 556 AQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSID 615

Query: 735 E----DDEEEEQEVDVEGHKPPEGEEEEEGRDPDDDEEEDEETEVLLGDPLVGGGRFLQG 790
           +     +      V   G    +G++    + P         + +              G
Sbjct: 616 DLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSI------------PGG 663

Query: 791 RGPSEKGSSRDRAPAVAGAFPLGLNSSRLLQEDGKLGD---PGSDLPPPPPPPLAPQKAS 847
             PS  GS            P+G N SR     G +     PGS +PP PP         
Sbjct: 664 PSPSPVGS------------PVGSNQSR----SGPISPASIPGSQMPPQPP--------- 698

Query: 848 GGGSSSPGSPVHHPSLEEQP 867
             GS S  S   HP+L + P
Sbjct: 699 --GSQSESS--SHPALSQSP 714



 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 160/664 (24%), Positives = 206/664 (31%), Gaps = 135/664 (20%)

Query: 243 ALPQPGAHPACHPLSSVKAAAVAAAAAVAGGGGLLGP----HLLGAPPPPPPPPPPLAEL 298
           A+P  G  PA  P         +AA A  G GG  GP    H     P         A  
Sbjct: 158 AVPGGGGGPAAVP--EFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAA 215

Query: 299 AGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVA 358
           AGAP +           D LQ +      S        S   A GG G GGGG GG    
Sbjct: 216 AGAPGSM----------DPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGG 265

Query: 359 GVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAF 418
           G G GAGAG GAGAGA    +         G  GG        GG         ++A   
Sbjct: 266 GGGGGAGAG-GAGAGAVAAAAAAAAAAAGGGGGGGY-------GG---------SSAGYG 308

Query: 419 SLCHKKEDAGAAAEALGGAGAGGAGAAPKAGLSGLFW--------PAGRKDAFYPPFCMF 470
            L   ++  G      GG GA     A     +G F         P+G            
Sbjct: 309 VLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSP 368

Query: 471 WPPRTPGGLPVPTYLQP--PPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPP 528
            P     G   P Y  P  PP PPS              Q     A  G AAG  +AA  
Sbjct: 369 SPMMRSYGGSYPEYSSPSAPPPPPS--------------QPQSQAAAAGAAAGGQQAAAG 414

Query: 529 PGQPPQVVANGPGSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAA 588
            G    + A    + P   A    S  A+    PG + G  S GS  P D +        
Sbjct: 415 MGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGR-SQGS--PMDPMVMKRPQLY 471

Query: 589 AAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFR-PVGGKDDAESLAKLHGASAGAP 647
             GS P      +  +P         GGSY      R P+G          + G + GA 
Sbjct: 472 GMGSNPHSQPQQSSPYP---------GGSYGPPGPQRYPIG----------IQGRTPGAM 512

Query: 648 HSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPG-----SERHHPAPPPPPPPP 702
              Q                +P Q       +PPQ  + G      +   P     P PP
Sbjct: 513 AGMQ----------------YPQQQ------MPPQYGQQGVSGYCQQGQQPYYSQQPQPP 550

Query: 703 PPPPLAQHPHHRGLLSPGGTSCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRD 762
             PP AQ+                PS+     +  ++  QE      +PP    +    D
Sbjct: 551 HLPPQAQY---------------LPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHED 595

Query: 763 PDDDEEEDEETEVLLG---DPLVGGGRFLQGRGPSEKGSSRDRAPAVAGA-FPLGLNSSR 818
            +  ++E   +   L    D L  G         S  GS+  +      A  P   ++S 
Sbjct: 596 LNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASP 655

Query: 819 LLQEDGKLGDPGSDLPPPPPPPLAPQKASGGGSSSPGSPVHHPSLEEQPSYKDSQKTKEN 878
            L        PG     P P P+     S    S P SP   P  +  P    SQ    +
Sbjct: 656 HLSSI-----PGG----PSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSS 706

Query: 879 NQVI 882
           +  +
Sbjct: 707 HPAL 710



 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 96/353 (27%), Positives = 115/353 (32%), Gaps = 59/353 (16%)

Query: 371 GAGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSLCHKKEDAGAA 430
           GAG   P+  P +  P  G       K    GG    P           L  K  D   A
Sbjct: 84  GAGGGAPQPGPDMEQPQHGG-----AKDSAAGGQADPPGP--------PLLSKPGDEDDA 130

Query: 431 AEALGGAGAGGAGAAPKAGLSGLFWP------AGRKDAFYPPFCMFWPPRTP-----GGL 479
              +G   AGG    P  G  G   P       G   A  P F  ++    P     GG 
Sbjct: 131 PPKMGEP-AGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGR 189

Query: 480 PVPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPP--GQPPQVVA 537
             P + Q   Q    +G     S A             GA GS +       G P     
Sbjct: 190 AGPCFDQHGGQQSPGMGMMHSASAAA-----------AGAPGSMDPLQNSHEGYPNSQCN 238

Query: 538 NGPGSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAA--GSGPA 595
           + PG   P   GG G          GG GG  +      A +VAAA A AAAA  G G  
Sbjct: 239 HYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGG 298

Query: 596 GSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTHPH 655
           G    +  +  L   R+ GGG         P GG   A SL+K   A+  A    Q    
Sbjct: 299 GYGGSSAGYGVLSSPRQQGGG-----MMMGPGGG--GAASLSK--AAAGSAAGGFQRFAG 349

Query: 656 HHHHPHHHHHHHHPPQPPSPLLLLPPQP---DEPGSERHHPAPPPPPPPPPPP 705
            + HP           P    LL  P P      GS   + +P  PPPPP  P
Sbjct: 350 QNQHP-------SGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQP 395



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 36/139 (25%), Positives = 44/139 (31%), Gaps = 24/139 (17%)

Query: 638 KLHGASAGAPHSAQTHPHHHHHPHHHH----HHHHPPQPPSPLLLLPPQPDEPGSERHHP 693
           K  G +  AP   Q H HHH H HHHH    HHHH  Q          Q  +   ++   
Sbjct: 12  KTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQ 71

Query: 694 APPP-----------PPPPPPPPPLAQHPHHRGLLSPGGTSCSYPSEDSSEDEDDEEEEQ 742
              P              P P P + Q  H     S  G     P         DE++  
Sbjct: 72  QQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDD-- 129

Query: 743 EVDVEGHKPPEGEEEEEGR 761
                   PP+  E   GR
Sbjct: 130 -------APPKMGEPAGGR 141



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 17/54 (31%), Positives = 26/54 (48%)

Query: 721  GTSCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPDDDEEEDEETE 774
            G    Y   D S+   D    ++ D +      G+EEE+    DDDEE++E+ E
Sbjct: 1678 GILMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECIDDDEEDEEDEE 1731


>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
           [Homo sapiens]
          Length = 2178

 Score = 76.6 bits (187), Expect = 1e-13
 Identities = 141/560 (25%), Positives = 181/560 (32%), Gaps = 127/560 (22%)

Query: 342 SGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFPGC 401
           +GG G GGGG GGG   G G G GAGAG GAGA    +       + G  GG      G 
Sbjct: 248 AGGGGGGGGGGGGGS-GGGGGGGGAGAG-GAGAGAVAAAAAAAAAAAGGGGG-----GGY 300

Query: 402 GGLFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGAGGAGAAPKAGLSGLF------- 454
           GG         ++A    L   ++  G      GG GA     A     +G F       
Sbjct: 301 GG---------SSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQN 351

Query: 455 -WPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQP--PPQPPSALGCALGESPALLRQAFL 511
             P+G             P     G   P Y  P  PP PPS              Q   
Sbjct: 352 QHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPS--------------QPQS 397

Query: 512 DLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPPPAGGAGSRDALFESPPGGSGGDCSA 571
             A  G AAG  +AA   G    + A    + P   A    S  A+    PG + G  S 
Sbjct: 398 QAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGR-SQ 456

Query: 572 GSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFR-PVGGK 630
           GS  P D +          GS P      +  +P         GGSY      R P+G +
Sbjct: 457 GS--PMDPMVMKRPQLYGMGSNPHSQPQQSSPYP---------GGSYGPPGPQRYPIGIQ 505

Query: 631 DDAESLAKLHGASAGAPHSAQTHPHHHH--------HPHHHHHHHHPPQPPSPLLLLPPQ 682
                  +  GA AG  +  Q  P  +               ++   PQPP     LPPQ
Sbjct: 506 ------GRTPGAMAGMQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPH----LPPQ 555

Query: 683 PD---EPGSERHHPAPPPPPP---PPPPPPLAQ-HPHHRGL-LSPGGTSCSYPSEDSSED 734
                    +R+ P              PPLA   P+H  L L       S P    S D
Sbjct: 556 AQYLPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSID 615

Query: 735 E----DDEEEEQEVDVEGHKPPEGEEEEEGRDPDDDEEEDEETEVLLGDPLVGGGRFLQG 790
           +     +      V   G    +G++    + P         + +              G
Sbjct: 616 DLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSI------------PGG 663

Query: 791 RGPSEKGSSRDRAPAVAGAFPLGLNSSRLLQEDGKLGD---PGSDLPPPPPPPLAPQKAS 847
             PS  GS            P+G N SR     G +     PGS +PP PP         
Sbjct: 664 PSPSPVGS------------PVGSNQSR----SGPISPASIPGSQMPPQPP--------- 698

Query: 848 GGGSSSPGSPVHHPSLEEQP 867
             GS S  S   HP+L + P
Sbjct: 699 --GSQSESS--SHPALSQSP 714



 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 160/664 (24%), Positives = 206/664 (31%), Gaps = 135/664 (20%)

Query: 243 ALPQPGAHPACHPLSSVKAAAVAAAAAVAGGGGLLGP----HLLGAPPPPPPPPPPLAEL 298
           A+P  G  PA  P         +AA A  G GG  GP    H     P         A  
Sbjct: 158 AVPGGGGGPAAVP--EFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAA 215

Query: 299 AGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVA 358
           AGAP +           D LQ +      S        S   A GG G GGGG GG    
Sbjct: 216 AGAPGSM----------DPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGG 265

Query: 359 GVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAF 418
           G G GAGAG GAGAGA    +         G  GG        GG         ++A   
Sbjct: 266 GGGGGAGAG-GAGAGAVAAAAAAAAAAAGGGGGGGY-------GG---------SSAGYG 308

Query: 419 SLCHKKEDAGAAAEALGGAGAGGAGAAPKAGLSGLFW--------PAGRKDAFYPPFCMF 470
            L   ++  G      GG GA     A     +G F         P+G            
Sbjct: 309 VLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSP 368

Query: 471 WPPRTPGGLPVPTYLQP--PPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPP 528
            P     G   P Y  P  PP PPS              Q     A  G AAG  +AA  
Sbjct: 369 SPMMRSYGGSYPEYSSPSAPPPPPS--------------QPQSQAAAAGAAAGGQQAAAG 414

Query: 529 PGQPPQVVANGPGSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAA 588
            G    + A    + P   A    S  A+    PG + G  S GS  P D +        
Sbjct: 415 MGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGR-SQGS--PMDPMVMKRPQLY 471

Query: 589 AAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFR-PVGGKDDAESLAKLHGASAGAP 647
             GS P      +  +P         GGSY      R P+G          + G + GA 
Sbjct: 472 GMGSNPHSQPQQSSPYP---------GGSYGPPGPQRYPIG----------IQGRTPGAM 512

Query: 648 HSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPG-----SERHHPAPPPPPPPP 702
              Q                +P Q       +PPQ  + G      +   P     P PP
Sbjct: 513 AGMQ----------------YPQQQ------MPPQYGQQGVSGYCQQGQQPYYSQQPQPP 550

Query: 703 PPPPLAQHPHHRGLLSPGGTSCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRD 762
             PP AQ+                PS+     +  ++  QE      +PP    +    D
Sbjct: 551 HLPPQAQY---------------LPSQSQQRYQPQQDMSQEGYGTRSQPPLAPGKPNHED 595

Query: 763 PDDDEEEDEETEVLLG---DPLVGGGRFLQGRGPSEKGSSRDRAPAVAGA-FPLGLNSSR 818
            +  ++E   +   L    D L  G         S  GS+  +      A  P   ++S 
Sbjct: 596 LNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASP 655

Query: 819 LLQEDGKLGDPGSDLPPPPPPPLAPQKASGGGSSSPGSPVHHPSLEEQPSYKDSQKTKEN 878
            L        PG     P P P+     S    S P SP   P  +  P    SQ    +
Sbjct: 656 HLSSI-----PGG----PSPSPVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQSESSS 706

Query: 879 NQVI 882
           +  +
Sbjct: 707 HPAL 710



 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 96/353 (27%), Positives = 115/353 (32%), Gaps = 59/353 (16%)

Query: 371 GAGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSLCHKKEDAGAA 430
           GAG   P+  P +  P  G       K    GG    P           L  K  D   A
Sbjct: 84  GAGGGAPQPGPDMEQPQHGG-----AKDSAAGGQADPPGP--------PLLSKPGDEDDA 130

Query: 431 AEALGGAGAGGAGAAPKAGLSGLFWP------AGRKDAFYPPFCMFWPPRTP-----GGL 479
              +G   AGG    P  G  G   P       G   A  P F  ++    P     GG 
Sbjct: 131 PPKMGEP-AGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGR 189

Query: 480 PVPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPP--GQPPQVVA 537
             P + Q   Q    +G     S A             GA GS +       G P     
Sbjct: 190 AGPCFDQHGGQQSPGMGMMHSASAAA-----------AGAPGSMDPLQNSHEGYPNSQCN 238

Query: 538 NGPGSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAA--GSGPA 595
           + PG   P   GG G          GG GG  +      A +VAAA A AAAA  G G  
Sbjct: 239 HYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGG 298

Query: 596 GSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTHPH 655
           G    +  +  L   R+ GGG         P GG   A SL+K   A+  A    Q    
Sbjct: 299 GYGGSSAGYGVLSSPRQQGGG-----MMMGPGGG--GAASLSK--AAAGSAAGGFQRFAG 349

Query: 656 HHHHPHHHHHHHHPPQPPSPLLLLPPQP---DEPGSERHHPAPPPPPPPPPPP 705
            + HP           P    LL  P P      GS   + +P  PPPPP  P
Sbjct: 350 QNQHP-------SGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQP 395



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 36/139 (25%), Positives = 44/139 (31%), Gaps = 24/139 (17%)

Query: 638 KLHGASAGAPHSAQTHPHHHHHPHHHH----HHHHPPQPPSPLLLLPPQPDEPGSERHHP 693
           K  G +  AP   Q H HHH H HHHH    HHHH  Q          Q  +   ++   
Sbjct: 12  KTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQ 71

Query: 694 APPP-----------PPPPPPPPPLAQHPHHRGLLSPGGTSCSYPSEDSSEDEDDEEEEQ 742
              P              P P P + Q  H     S  G     P         DE++  
Sbjct: 72  QQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDD-- 129

Query: 743 EVDVEGHKPPEGEEEEEGR 761
                   PP+  E   GR
Sbjct: 130 -------APPKMGEPAGGR 141



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 17/54 (31%), Positives = 26/54 (48%)

Query: 721  GTSCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPDDDEEEDEETE 774
            G    Y   D S+   D    ++ D +      G+EEE+    DDDEE++E+ E
Sbjct: 1625 GILMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECIDDDEEDEEDEE 1678


>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
           [Homo sapiens]
          Length = 2191

 Score = 76.3 bits (186), Expect = 1e-13
 Identities = 169/683 (24%), Positives = 215/683 (31%), Gaps = 171/683 (25%)

Query: 243 ALPQPGAHPACHPLSSVKAAAVAAAAAVAGGGGLLGP----HLLGAPPPPPPPPPPLAEL 298
           A+P  G  PA  P         +AA A  G GG  GP    H     P         A  
Sbjct: 158 AVPGGGGGPAAVP--EFNNYYGSAAPASGGPGGRAGPCFDQHGGQQSPGMGMMHSASAAA 215

Query: 299 AGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVA 358
           AGAP +           D LQ +      S        S   A GG G GGGG GG    
Sbjct: 216 AGAPGSM----------DPLQNSHEGYPNSQCNHYPGYSRPGAGGGGGGGGGGGGGSGGG 265

Query: 359 GVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAF 418
           G G GAGAG GAGAGA    +         G  GG        GG         ++A   
Sbjct: 266 GGGGGAGAG-GAGAGAVAAAAAAAAAAAGGGGGGGY-------GG---------SSAGYG 308

Query: 419 SLCHKKEDAGAAAEALGGAGAGGAGAAPKAGLSGLFW--------PAGRKDAFYPPFCMF 470
            L   ++  G      GG GA     A     +G F         P+G            
Sbjct: 309 VLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSP 368

Query: 471 WPPRTPGGLPVPTYLQP--PPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPP 528
            P     G   P Y  P  PP PPS              Q     A  G AAG  +AA  
Sbjct: 369 SPMMRSYGGSYPEYSSPSAPPPPPS--------------QPQSQAAAAGAAAGGQQAAAG 414

Query: 529 PGQPPQVVANGPGSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAA 588
            G    + A    + P   A    S  A+    PG + G  S GS  P D +        
Sbjct: 415 MGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGR-SQGS--PMDPMVMKRPQLY 471

Query: 589 AAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFR-PVGGKDDAESLAKLHGASAGAP 647
             GS P      +  +P         GGSY      R P+G          + G + GA 
Sbjct: 472 GMGSNPHSQPQQSSPYP---------GGSYGPPGPQRYPIG----------IQGRTPGAM 512

Query: 648 HSAQTHPHHHHHPHHHHHHHHPPQPPS-------PLLLLPPQPDEPG-----SERHHPAP 695
              Q                +P Q  S          L+PPQ  + G      +   P  
Sbjct: 513 AGMQ----------------YPQQQDSGDATWKETFWLMPPQYGQQGVSGYCQQGQQPYY 556

Query: 696 PPPPPPPPPPPLAQHPHHRGLLSPGGTSCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEG- 754
              P PP  PP AQ+                PS+     +  ++  QE      +PP   
Sbjct: 557 SQQPQPPHLPPQAQY---------------LPSQSQQRYQPQQDMSQEGYGTRSQPPLAP 601

Query: 755 -----------EEEEEGRDPDDDEEEDE---ETEVLLGDPL-VGGGRFLQG--RGPSEKG 797
                      ++E     PD     D+    TE  L   +   G    QG    P++  
Sbjct: 602 GKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSP 661

Query: 798 SSRDRAPAVAG----------AFPLGLNSSRLLQEDGKLGD---PGSDLPPPPPPPLAPQ 844
            S   +P ++             P+G N SR     G +     PGS +PP PP      
Sbjct: 662 FSPHASPHLSSIPGGPSPSPVGSPVGSNQSR----SGPISPASIPGSQMPPQPP------ 711

Query: 845 KASGGGSSSPGSPVHHPSLEEQP 867
                GS S  S   HP+L + P
Sbjct: 712 -----GSQSESS--SHPALSQSP 727



 Score = 57.0 bits (136), Expect = 9e-08
 Identities = 96/353 (27%), Positives = 115/353 (32%), Gaps = 59/353 (16%)

Query: 371 GAGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSLCHKKEDAGAA 430
           GAG   P+  P +  P  G       K    GG    P           L  K  D   A
Sbjct: 84  GAGGGAPQPGPDMEQPQHGG-----AKDSAAGGQADPPGP--------PLLSKPGDEDDA 130

Query: 431 AEALGGAGAGGAGAAPKAGLSGLFWP------AGRKDAFYPPFCMFWPPRTP-----GGL 479
              +G   AGG    P  G  G   P       G   A  P F  ++    P     GG 
Sbjct: 131 PPKMGEP-AGGRYEHPGLGALGTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPGGR 189

Query: 480 PVPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPP--GQPPQVVA 537
             P + Q   Q    +G     S A             GA GS +       G P     
Sbjct: 190 AGPCFDQHGGQQSPGMGMMHSASAAA-----------AGAPGSMDPLQNSHEGYPNSQCN 238

Query: 538 NGPGSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAA--GSGPA 595
           + PG   P   GG G          GG GG  +      A +VAAA A AAAA  G G  
Sbjct: 239 HYPGYSRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGAGAGAVAAAAAAAAAAAGGGGGG 298

Query: 596 GSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTHPH 655
           G    +  +  L   R+ GGG         P GG   A SL+K   A+  A    Q    
Sbjct: 299 GYGGSSAGYGVLSSPRQQGGG-----MMMGPGGG--GAASLSK--AAAGSAAGGFQRFAG 349

Query: 656 HHHHPHHHHHHHHPPQPPSPLLLLPPQP---DEPGSERHHPAPPPPPPPPPPP 705
            + HP           P    LL  P P      GS   + +P  PPPPP  P
Sbjct: 350 QNQHP-------SGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPPSQP 395



 Score = 44.3 bits (103), Expect = 6e-04
 Identities = 36/139 (25%), Positives = 44/139 (31%), Gaps = 24/139 (17%)

Query: 638 KLHGASAGAPHSAQTHPHHHHHPHHHH----HHHHPPQPPSPLLLLPPQPDEPGSERHHP 693
           K  G +  AP   Q H HHH H HHHH    HHHH  Q          Q  +   ++   
Sbjct: 12  KTVGEAPAAPPHQQHHHHHHAHHHHHHAHHLHHHHALQQQLNQFQQQQQQQQQQQQQQQQ 71

Query: 694 APPP-----------PPPPPPPPPLAQHPHHRGLLSPGGTSCSYPSEDSSEDEDDEEEEQ 742
              P              P P P + Q  H     S  G     P         DE++  
Sbjct: 72  QQHPISNNNSLGGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPGPPLLSKPGDEDD-- 129

Query: 743 EVDVEGHKPPEGEEEEEGR 761
                   PP+  E   GR
Sbjct: 130 -------APPKMGEPAGGR 141



 Score = 32.7 bits (73), Expect = 1.7
 Identities = 17/54 (31%), Positives = 26/54 (48%)

Query: 721  GTSCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPDDDEEEDEETE 774
            G    Y   D S+   D    ++ D +      G+EEE+    DDDEE++E+ E
Sbjct: 1638 GILMEYEVGDPSQKALDHNAARKDDSQSLADDSGKEEEDAECIDDDEEDEEDEE 1691


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score = 75.9 bits (185), Expect = 2e-13
 Identities = 161/672 (23%), Positives = 196/672 (29%), Gaps = 183/672 (27%)

Query: 271  AGGGGLLGPHLLGAPPPPPPPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLS 330
            +G  G  GP  +G+  P  PP P                     D +  E  VV A   +
Sbjct: 597  SGAAGPTGP--IGSRGPSGPPGP---------------------DGNKGEPGVVGAVGTA 633

Query: 331  AAAASLSVAAASGGAGTGGG-------------------GAGG--GCVAGVGVGAGAGAG 369
              +    +    G AG  GG                   GA G  G V   G     G  
Sbjct: 634  GPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDR 693

Query: 370  AGAGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSLCHKKEDAGA 429
              AGA GP   P  P  S G  G V       G   P+ +  PA AA       +  A  
Sbjct: 694  GEAGAAGPAG-PAGPRGSPGERGEV-------GPAGPNGFAGPAGAAGQPGAKGERGAKG 745

Query: 430  AAEALGGAG-AGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPG-GLPVPTYLQP 487
                 G  G  G  GAA  AG +G   PAG +    PP    +P      G P P+ +  
Sbjct: 746  PKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISG 805

Query: 488  PPQPPSALGCA--------------LGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQP- 532
            PP PP   G                 GE  A+    F     P G AG+A    PPG P 
Sbjct: 806  PPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAG---PPGTPG 862

Query: 533  PQVVANGPG----------SGPPPPAGGAGSRDAL-FESPPGGSGGDCSAGSTPPADSVA 581
            PQ +   PG           G P  AG  G    L    PPG  G   + GS     +  
Sbjct: 863  PQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPG 922

Query: 582  AAGAGAAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHG 641
             AG        GP G            +G+    G   +     PVG             
Sbjct: 923  EAGRDGNPGNDGPPGR-----------DGQPGHKGERGYPGNIGPVG------------- 958

Query: 642  ASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPL----LLLPPQPDEPGSERHHPAPPP 697
             +AGAP      PH    P   H +     P  P+     + P  P  P   R     P 
Sbjct: 959  -AAGAPG-----PHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQGIRGDKGEPG 1012

Query: 698  PPPPPPPPPLAQHPHHRGLLSPGGTSCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEE 757
               P   P L  H   +GL    G               D+     V   G + P G   
Sbjct: 1013 EKGPRGLPGLKGHNGLQGLPGIAG------------HHGDQGAPGSVGPAGPRGPAGPSG 1060

Query: 758  EEGRDPDDDEEEDEETEVLLGDPLVGGGRFLQGRGPSEKGSSRDRAPAVAGAFPLGLNSS 817
              G+D                                     R   P   G  P G+   
Sbjct: 1061 PAGKD------------------------------------GRTGHPGTVG--PAGIR-- 1080

Query: 818  RLLQEDGKLGDPGSDLPPPPPPPLAPQKASGGGSS--------SPGSPVHHPSLEEQPSY 869
                  G  G  G   PP PP P  P   SGGG              P   PSL  +   
Sbjct: 1081 ------GPQGHQGPAGPPGPPGPPGPPGVSGGGYDFGYDGDFYRADQPRSAPSLRPKDYE 1134

Query: 870  KDSQKTKENNQV 881
             D+     NNQ+
Sbjct: 1135 VDATLKSLNNQI 1146



 Score = 59.3 bits (142), Expect = 2e-08
 Identities = 152/571 (26%), Positives = 186/571 (32%), Gaps = 123/571 (21%)

Query: 341 ASGGAGTGGG-GAGG--GCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQK 397
           A G  GT G  GA G  G    VG    AGA    G+ GP   P  P+ S G  G     
Sbjct: 203 APGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVG-PAGPIGSAGPPG----- 256

Query: 398 FPGCGGLFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAG-AGGAGAAPKAGLSGLFWP 456
           FPG  G                    K + GA    +G AG AG AG   + GL GL  P
Sbjct: 257 FPGAPG-------------------PKGEIGA----VGNAGPAGPAGPRGEVGLPGLSGP 293

Query: 457 AGRKDAFYPPFCMFWPPRTPG-----------GLPVPTYLQPPPQPPSALGCALGESPAL 505
            G             PP  PG           GLP        P P    G  +G + A 
Sbjct: 294 VG-------------PPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPG-PVGAAGAT 339

Query: 506 LRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPPPAGGAGSR----DALFESP 561
             +  +    P G+ G +     PG        GP  GPP P+G  G R    +A    P
Sbjct: 340 GARGLVGEPGPAGSKGESGNKGEPGSA------GP-QGPPGPSGEEGKRGPNGEAGSAGP 392

Query: 562 PGGSGGDCSAGS--TPPADSVAAA-GAGAAAAGSGPAGSRVP-----APHHPHLLEGRKA 613
           PG  G   S GS   P AD  A   G   +   SGPAG R P      P  P L+  R  
Sbjct: 393 PGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGL 452

Query: 614 GGGSYHHSSAFRPVGGKDDAESLAKLHGASAG-APHSAQTHPHHHHHPHHHHHHHHP-PQ 671
            G   +   A     GK+    L  + G      P  A+  P +   P        P   
Sbjct: 453 PGSPGNIGPA-----GKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKN 507

Query: 672 PPSPLLLLPPQPDEPGSERHHPAPPPPPPP----------PPPPPLAQHPHHRGLLSPGG 721
                  L      PG + ++ A  PP P           PP PP  Q     GL  P G
Sbjct: 508 GDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQ-----GLPGPSG 562

Query: 722 TSCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEG-------RDPDDDEEEDEETE 774
            +             +          G + P GE    G       R P      D    
Sbjct: 563 PAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNK- 621

Query: 775 VLLGDPLVGGGRFLQG-RGPSEKGSSRDRAPAVAGAFPLGLNSSRLLQEDGKLGDPGSDL 833
              G+P V G     G  GPS     R  A    G    G    R     G++G+PG D 
Sbjct: 622 ---GEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLR-----GEIGNPGRDG 673

Query: 834 PPPPPPPL---APQKASG----GGSSSPGSP 857
               P  +    P  A+G     G++ P  P
Sbjct: 674 ARGAPGAVGAPGPAGATGDRGEAGAAGPAGP 704



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 79/298 (26%), Positives = 100/298 (33%), Gaps = 50/298 (16%)

Query: 338 VAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQK 397
           +A A G  G  G     G     GV  G G     G  GP  +  +P PS G  G V + 
Sbjct: 515 LAGARGAPGPDGNNGAQGPPGPQGVQGGKGE---QGPPGPPGFQGLPGPS-GPAGEVGK- 569

Query: 398 FPGCGGLFPHPYTFPAAAAAFSLCHKKEDAGAAAEA--LGGAGAGGA----GAAPKAGLS 451
            PG  GL    +  P  A          ++GAA     +G  G  G     G   + G+ 
Sbjct: 570 -PGERGLHGE-FGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVV 627

Query: 452 GLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGESPALLRQAFL 511
           G    AG              P  P GLP        P      G      P L      
Sbjct: 628 GAVGTAG--------------PSGPSGLPGERGAAGIPGGKGEKG-----EPGLRG---- 664

Query: 512 DLAEPG--------GAAGSAEAAPPPGQPPQVVANGPGSGPPPPAGGAGSRDALFESPPG 563
           ++  PG        GA G+   A   G   +  A GP +GP  P G  G R  +  + P 
Sbjct: 665 EIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGP-AGPAGPRGSPGERGEVGPAGPN 723

Query: 564 GSGGDCSAGSTPPADSVAAA----GAGAAAAGSGPAGSRVPA-PHHPHLLEGRKAGGG 616
           G  G   A   P A     A    G       +GP G+  PA P+ P    G +  GG
Sbjct: 724 GFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGG 781



 Score = 40.4 bits (93), Expect = 0.008
 Identities = 92/349 (26%), Positives = 105/349 (30%), Gaps = 67/349 (19%)

Query: 272 GGGGLLGPHLLGAPPPPPPPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSA 331
           G  G  GP   G P PP PP PP   L G                    AA      +  
Sbjct: 51  GRDGEDGP--TGPPGPPGPPGPP--GLGG------------------NFAAQYDGKGVGL 88

Query: 332 AAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIP------- 384
               + +    G  G  G     G     G     G    AGA+GP   P          
Sbjct: 89  GPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPG 148

Query: 385 VPSKGSFGGVL-----QKFPGCGGLFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGA 439
            P +    GV+     + FPG  GL      F        L   K   GA     G  GA
Sbjct: 149 KPGRPGERGVVGPQGARGFPGTPGL----PGFKGIRGHNGLDGLKGQPGAPG-VKGEPGA 203

Query: 440 GGAGAAP-KAGLSGLFWPAGRKDAFYPPFCMFWPPRT-PGGLPVPTYLQPPPQPPSALGC 497
            G    P + G  GL    GR  A  P           P G   P     PP  P A G 
Sbjct: 204 PGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPG- 262

Query: 498 ALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPG-SGPPPPAGGAGSRDA 556
             GE                GA G+A  A P G  P+     PG SGP  P G  G+   
Sbjct: 263 PKGEI---------------GAVGNAGPAGPAG--PRGEVGLPGLSGPVGPPGNPGANGL 305

Query: 557 LFESPPGGSGGDCSAGSTP-------PADSVAAAGAGAAAAGSGPAGSR 598
                  G  G   A   P       P  +  A GA       GPAGS+
Sbjct: 306 TGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSK 354



 Score = 37.4 bits (85), Expect = 0.071
 Identities = 30/102 (29%), Positives = 39/102 (38%), Gaps = 16/102 (15%)

Query: 516 PGGAAGSAEAAPPPGQPPQVVANGPGS-----GPPPPAGGAGSRDALFESPP-------- 562
           P G  G      PPG P +   +GP       GPP P G  G+  A ++           
Sbjct: 34  PAGDRGPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPM 93

Query: 563 ---GGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPA 601
              G  G   +AG+  P      AG       +GPAG+R PA
Sbjct: 94  GLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPA 135



 Score = 35.8 bits (81), Expect = 0.21
 Identities = 56/217 (25%), Positives = 73/217 (33%), Gaps = 40/217 (18%)

Query: 680 PPQPDEPGSERHHPAPPPPPPPPPPPPL-----AQH--------PHHRGLLSPGGT--SC 724
           PP P     E     PP PP PP PP L     AQ+        P   GL+ P G   + 
Sbjct: 46  PPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPRGPPGAA 105

Query: 725 SYPSEDSSEDEDDEE-EEQEVDVEGHKPPEGEEEEEGRD--PDDDEEEDEETEV------ 775
             P     +    E  E  +    G + P G   + G D  P       E   V      
Sbjct: 106 GAPGPQGFQGPAGEPGEPGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGAR 165

Query: 776 -LLGDPLVGGGRFLQGRGPSEKGSSRDRAPAVAG--------AFPLGLNSSRLLQEDGKL 826
              G P + G + ++G    +    +  AP V G          P    +  L  E G++
Sbjct: 166 GFPGTPGLPGFKGIRGHNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRV 225

Query: 827 GDP------GSDLPPPPPPPLAPQKASGGGSSSPGSP 857
           G P      GSD    P  P  P   S G    PG+P
Sbjct: 226 GAPGPAGARGSDGSVGPVGPAGP-IGSAGPPGFPGAP 261


>gi|122937424 one cut homeobox 3 [Homo sapiens]
          Length = 494

 Score = 74.3 bits (181), Expect = 5e-13
 Identities = 94/319 (29%), Positives = 107/319 (33%), Gaps = 106/319 (33%)

Query: 329 LSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSK 388
           L A  ASL      GG G GGGGAG       G G    AG GA  +G  + P+ P    
Sbjct: 46  LVAGMASL----LDGGGGGGGGGAG-------GAGGAGSAGGGADFRGELAGPLHPAM-- 92

Query: 389 GSFGGVLQKFPGCGG----LFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGAGGAGA 444
               G+  + PG GG    L P  +  P AA A      K    AAA A+ GA  G    
Sbjct: 93  ----GMACEAPGLGGTYTTLTPLQHLPPLAAVA-----DKFHQHAAAAAVAGAHGG---- 139

Query: 445 APKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGESPA 504
                                          P   P P    PPP PP  L  ++  S  
Sbjct: 140 ------------------------------HPHAHPHPAAAPPPPPPPQRLAASVSGSFT 169

Query: 505 LLRQAFLDLAEPGGAAG-------------------------SAEAAPPPGQPPQVVANG 539
           L+R     LA  G   G                          A   PPP  PP + A G
Sbjct: 170 LMRDERAALASVGHLYGPYGKELPAMGSPLSPLPNALPPALHGAPQPPPPPPPPPLAAYG 229

Query: 540 P-----GSGPPPPAGG-------AGSRDALFESPPGGSGGDCS--------AGSTPPADS 579
           P     G    PPA           + DAL    PGG GG  S        AG   P   
Sbjct: 230 PPGHLAGDKLLPPAAFEPHAALLGRAEDALARGLPGGGGGTGSGGAGSGSAAGLLAPLGG 289

Query: 580 VAAAGA-GAAAAGSGPAGS 597
           +AAAGA G    G GP GS
Sbjct: 290 LAAAGAHGPHGGGGGPGGS 308



 Score = 67.8 bits (164), Expect = 5e-11
 Identities = 61/170 (35%), Positives = 70/170 (41%), Gaps = 39/170 (22%)

Query: 238 GSRKRALPQPGAHPACHPLSSVKAAAVAAA--------AAVAGGGGLLGPH--------- 280
           G    A P P A P   P     AA+V+ +        AA+A  G L GP+         
Sbjct: 138 GGHPHAHPHPAAAPPPPPPPQRLAASVSGSFTLMRDERAALASVGHLYGPYGKELPAMGS 197

Query: 281 ------------LLGAPPPPPPPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVA-AA 327
                       L GAP PPPPPPPP       P A +  P     D  L  AA    AA
Sbjct: 198 PLSPLPNALPPALHGAPQPPPPPPPP-------PLAAYGPPGHLAGDKLLPPAAFEPHAA 250

Query: 328 SLSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGP 377
            L  A  +L+     GG GTG GGAG G  A  G+ A  G  A AGA GP
Sbjct: 251 LLGRAEDALARGLPGGGGGTGSGGAGSGSAA--GLLAPLGGLAAAGAHGP 298



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 63/245 (25%), Positives = 77/245 (31%), Gaps = 61/245 (24%)

Query: 511 LDLAEPGGAAGSAEAAP----PPGQPPQVVANGPGSGPPPPAGGAGSRDALFESPPGGSG 566
           L L   GG    A A       PG      A   G   P   G      +L +   GG G
Sbjct: 3   LSLESLGGLHSVAHAQAGELLSPGHARSAAAQHRGLVAPGRPGLVAGMASLLDGGGGGGG 62

Query: 567 GDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLLEGRKAGG--GSYHHSSAF 624
           G              A GAG+A  G+   G  +  P HP +    +A G  G+Y   +  
Sbjct: 63  GGAGG----------AGGAGSAGGGADFRGE-LAGPLHPAMGMACEAPGLGGTYTTLTPL 111

Query: 625 RPVGGKDDAESLAKLHGASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLL------ 678
           + +            H A+A    +   HPH H HP        PP PP P  L      
Sbjct: 112 QHLPPLAAVADKFHQHAAAAAVAGAHGGHPHAHPHPAAA-----PPPPPPPQRLAASVSG 166

Query: 679 --------------------------------LPPQPDEPGSERHHPAPPPPPPPPPPPP 706
                                           L P P+      H  AP PPPPPPPPP 
Sbjct: 167 SFTLMRDERAALASVGHLYGPYGKELPAMGSPLSPLPNALPPALHG-APQPPPPPPPPPL 225

Query: 707 LAQHP 711
            A  P
Sbjct: 226 AAYGP 230


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 73.9 bits (180), Expect = 7e-13
 Identities = 114/473 (24%), Positives = 154/473 (32%), Gaps = 116/473 (24%)

Query: 482  PTYLQPPPQPPS--------ALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPP 533
            P+Y +P   PP         ++G A  + P L   A +  +      GS +  PPP   P
Sbjct: 870  PSYERPSFLPPGPGLMLRQKSIGAAEDDRPYLAPPA-MKFSRSLSVPGSEDIPPPPTTSP 928

Query: 534  QVVANGPGSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSG 593
                  P S PP P+    S   L  SP GG     S G  P       A + A+  G  
Sbjct: 929  P---EPPYSTPPVPS----SSGRLTPSPRGGPFNPGSGGPLP-------ASSPASFDGPS 974

Query: 594  PAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTH 653
            P  +RV +               S +HS    P                           
Sbjct: 975  PPDTRVGSREK------------SLYHSGPLPPA-------------------------- 996

Query: 654  PHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAPPP-----PPPP------- 701
               HHHP HHHHHH PP  P      PP P E  +      PPP     P P        
Sbjct: 997  ---HHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGG 1053

Query: 702  -PPPPPLAQHPHHRGLLSPGGTSCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEG 760
             P P P A  P H G    GG S   P+         +   +      + P       +G
Sbjct: 1054 GPSPTPGAPSPSHHGSAGGGGGSSQGPAL-----RYFQLPPRAASAAMYVPARSGRGRKG 1108

Query: 761  RDPDDDEEEDEETEVLLGDPLVGGGRFLQGRGPSEKGSSRDRAPAVAG-------AFPLG 813
                  + E        G+P  GGG  L         +S    PAVA          P  
Sbjct: 1109 PLVKQTKVE--------GEPQKGGG--LPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTI 1158

Query: 814  LNSSRLLQEDGKLGDPGSDLPPPPPPPLAPQKASGGGSSSPG------------SPVHHP 861
            +  +      G+    GS     PP    P    GGG SSP             SPV  P
Sbjct: 1159 IIKAPSTSSSGR-SSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPSPVPTP 1217

Query: 862  SLEEQPSYKDSQKTKENNQVIVSTKDDNSFSDKNKEHS--FFITDS-DASGGD 911
            +    P+  D   ++    ++ + + +  + ++ +  S  F  TD+ D  GGD
Sbjct: 1218 ASPSGPATLDF-TSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDEDGGD 1269



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 89/365 (24%), Positives = 125/365 (34%), Gaps = 72/365 (19%)

Query: 428  GAAAEALGGAGAGGAGAA-----------PKAGLSGLFWPA----GRKDAFYPPFCMFWP 472
            GA + +  G+  GG G++           P+A  + ++ PA    GRK        +   
Sbjct: 1060 GAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKVEGE 1119

Query: 473  PRTPGGLP-VPTYLQPP-PQPPSALGCALGES----PALLRQAFLDLAEPGGAAGSAEAA 526
            P+  GGLP  P+   P  PQPP A+     ++    P ++ +A    +    + GS+  A
Sbjct: 1120 PQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEA 1179

Query: 527  PPPGQPPQVVANGPGSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPA--DSVAAAG 584
             PP QP      G G   P PA       A+   PP  S     A  + PA  D  +  G
Sbjct: 1180 EPPTQPEPTGGGGGGGSSPSPA------PAMSPVPPSPSPVPTPASPSGPATLDFTSQFG 1233

Query: 585  AGAAAAGSGPAGSRVPAPHHPHLLEGRKAG---------------GGSYHHSSAFRPVGG 629
            A    A     G +  A     L     AG               G    HS +     G
Sbjct: 1234 AALVGAARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSIDE--G 1291

Query: 630  KDDAESLAKLHGASAGAPHSAQTHPHHHH---------------HPHHHHHHHHPPQPPS 674
               AE   +L  A +GA +         +                P  H        P S
Sbjct: 1292 MFSAEPYLRLESAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPAS 1351

Query: 675  PLLL--------LPPQPDEPGSERHHPAPPPP---PPPPPPPPLAQHPHHRGLLSPGGTS 723
            PL L        L    +  G+ +  P PP P    PPP P   + H HH  +L   G S
Sbjct: 1352 PLGLALAARERALKESSEGGGAPQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGAS 1411

Query: 724  CSYPS 728
               P+
Sbjct: 1412 PPDPA 1416



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 89/336 (26%), Positives = 112/336 (33%), Gaps = 46/336 (13%)

Query: 245  PQPGAHPACHPLSSVKAAAVAAAAAVAGGGG-----------LLGPHLLGAPPPPPPPPP 293
            P P       PL  V   AVAAA                    L      AP  P PP P
Sbjct: 1591 PLPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGP 1650

Query: 294  PLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAG 353
            P A  A AP A    P      DS  E     ++S        S +  S  +  GGG AG
Sbjct: 1651 P-APAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAG 1709

Query: 354  GGCVAGVGVGAG------------AGAGAGAGAKGPRSYPVIPVPSK------GSFGGVL 395
            GG  AG GV +G              A  G+   GP   P +  PSK      G+ GG+ 
Sbjct: 1710 GGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLR 1769

Query: 396  QKFPGCGGLFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGAGGAGAAPKAGLSGLFW 455
               PG  G    P T    +   S+     D   A  A  G    G    P A +     
Sbjct: 1770 ---PGPSGGLRDPVT--PTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVA-VEPEVP 1823

Query: 456  PAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGESPALLRQAFLDLAE 515
            P     A   P  +   P   G  P P  L  P   P A   A  ++ +++ +    L +
Sbjct: 1824 PVPLPTASSLPRKLL--PWEEGPGPPPPPLPGPLAQPQASALATVKA-SIISELSSKLQQ 1880

Query: 516  PGGAAGSAEAAPPPGQPPQVVANGPGSGPPPPAGGA 551
             GG++ +  A P           G G G     GGA
Sbjct: 1881 FGGSSAAGGALP-------WARGGSGGGGDSHHGGA 1909



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 160/687 (23%), Positives = 197/687 (28%), Gaps = 183/687 (26%)

Query: 272  GGGGLLGPHLLGAPPPPPPPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSA 331
            GGG    P    +P PP P P P       P       +F         AA+V AA    
Sbjct: 1193 GGGSSPSPAPAMSPVPPSPSPVPTPASPSGPATLDFTSQFG--------AALVGAARREG 1244

Query: 332  A-------AASLSVAAASGGAGTGGGGAGGGCVAGVGV--------------------GA 364
                     ++L ++  +G    G GG G G   G  +                     A
Sbjct: 1245 GWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLESA 1304

Query: 365  GAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSLCHKK 424
            G+GAG G    G R+Y           GG    F     L P P   P    A       
Sbjct: 1305 GSGAGYGGYGAGSRAY---------GGGGGSSAFTSF--LPPRPLVHPLTGKALDPASPL 1353

Query: 425  EDAGAAAE-ALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPT 483
              A AA E AL  +  GG    P                         PPR P     P 
Sbjct: 1354 GLALAARERALKESSEGGGAPQP-------------------------PPRPPS----PR 1384

Query: 484  YLQPPPQP----PSA-------LGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQ- 531
            Y  PPP P    P A       L  A    PA  R+     A  G    S  A+PP  + 
Sbjct: 1385 YEAPPPTPHHHSPHAHHEPVLRLWGASPPDPA--RRELGYRAGLGSQEKSLPASPPAARR 1442

Query: 532  ------PPQVVANGP-----GSGPPPPAGGAGS--RDALFESPPG-----------GSGG 567
                  PP     GP     G+ PP P  G     R A  E P                 
Sbjct: 1443 SLLHRLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPRA 1502

Query: 568  DCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPV 627
              ++G  PP++       G       P  S  P+P  P   E                P 
Sbjct: 1503 PVTSGRGPPSED------GPGVPPPSPRRSVPPSPTSPRASEENGLP------LLVLPPP 1550

Query: 628  GGKDDAESLAKLHGASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPG 687
                D E    L       P            P         P PP PL      PD P 
Sbjct: 1551 APSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPL-------TPGPPHPL------PDTP- 1596

Query: 688  SERHHPAPPPPPPPPPPPPLAQHPHHRGLLSPGGTSCSYPSEDSSEDEDDEEEEQEVDVE 747
                  AP  P PP PPP +A  P    L S   +  SY SE ++  +       +    
Sbjct: 1597 ------APATPLPPVPPPAVAAAP--PTLDSTASSLTSYDSEVATLTQGASAAPGDPHPP 1648

Query: 748  GHKPP-------------------EGEEEEEGRDPDDDEEEDEETEVLLGDPLVGGGRFL 788
            G   P                    G EE + R   D   E   +   L      GG   
Sbjct: 1649 GPPAPAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSA 1708

Query: 789  QGRGPSEKGSSRDRAPAVAGAFPLGLNSSRLLQEDGKLGDPGSDLPPPPPPPLAPQK--- 845
             G G +  G+     P +   +   L+     Q  G    PG   PP PP  + P K   
Sbjct: 1709 GGGGGA--GAGVASGPELLDTYVAYLDG----QAFGGSSTPG---PPYPPQLMTPSKLRG 1759

Query: 846  ----ASGGGSSSPGSPVHHPSLEEQPS 868
                ASGG    P   +  P     P+
Sbjct: 1760 RALGASGGLRPGPSGGLRDPVTPTSPT 1786



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 127/485 (26%), Positives = 153/485 (31%), Gaps = 94/485 (19%)

Query: 278  GPHLLGAPPPPP--------PPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAA-S 328
            G  L   P PPP         P  PL    G PH     P        +   AV AA  +
Sbjct: 1559 GEFLFVEPLPPPLEFSNSFEKPESPLTP--GPPHPLPDTPAPATPLPPVPPPAVAAAPPT 1616

Query: 329  LSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSK 388
            L + A+SL+   +     T G  A  G     G  A A     A   GP        P  
Sbjct: 1617 LDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPD-------PPP 1669

Query: 389  GSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGAGGAGAAPKA 448
            G+  G+ +          HP    ++A+  S     E  G+A    GG G  GAG A   
Sbjct: 1670 GTDSGIEEVDSRSSS--DHPLETISSASTLSSL-SAEGGGSA----GGGGGAGAGVASGP 1722

Query: 449  GLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQPPPQ---PPSALGCALGESPAL 505
             L   +         Y     F    TPG    P Y   PPQ   P    G ALG S  L
Sbjct: 1723 ELLDTY-------VAYLDGQAFGGSSTPG----PPY---PPQLMTPSKLRGRALGASGGL 1768

Query: 506  LRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGS---------GPPPPAGGAGSRDA 556
                      PG + G  +   P    P V   G G+           PP AG AG   A
Sbjct: 1769 ---------RPGPSGGLRDPVTPTS--PTVSVTGAGTDGLLALRACSGPPTAGVAGGPVA 1817

Query: 557  LF-ESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAP---HHPHLLEGRK 612
            +  E PP            P A S+          G GP    +P P        L   K
Sbjct: 1818 VEPEVPPV---------PLPTASSLPRKLL-PWEEGPGPPPPPLPGPLAQPQASALATVK 1867

Query: 613  AGGGSYHHSSAFRPVGGKDDAE-SLAKLHGASAGAPHSAQTHPHHHHHPHHHHHHHHPPQ 671
            A   S   SS  +  GG   A  +L    G S G   S            HH    + P+
Sbjct: 1868 ASIIS-ELSSKLQQFGGSSAAGGALPWARGGSGGGGDS------------HHGGASYVPE 1914

Query: 672  PPSPLLLLPPQPDEPGSERHHPAPPP----PPPPPPPPPLAQHPHHRGLLSPGGTSCSYP 727
              S L       D   S    P        P PP PP P           +PG TS S  
Sbjct: 1915 RTSSLQRQRLSDDSQSSLLSKPVSSLFQNWPKPPLPPLPTGTGVSPTAAAAPGATSPSAS 1974

Query: 728  SEDSS 732
            S  +S
Sbjct: 1975 SSSTS 1979



 Score = 38.9 bits (89), Expect = 0.024
 Identities = 45/160 (28%), Positives = 53/160 (33%), Gaps = 31/160 (19%)

Query: 477  GGLPVPTYLQPPPQPPSALGCALGES--PALL------RQAFLDLAEPG----GAAG--- 521
            GG P PT   P P    + G   G S  PAL       R A   +  P     G  G   
Sbjct: 1052 GGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLV 1111

Query: 522  -----SAEAAPPPGQPPQVVANGPGSGPPPPAGGAGSR-------DALFESPPGGSGGDC 569
                   E     G PP      P S  PPPA  A S          + ++P   S G  
Sbjct: 1112 KQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRS 1171

Query: 570  SAGST----PPADSVAAAGAGAAAAGSGPAGSRVPAPHHP 605
            S GS+    PP       G G   +   PA +  P P  P
Sbjct: 1172 SQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSP 1211



 Score = 35.8 bits (81), Expect = 0.21
 Identities = 27/75 (36%), Positives = 33/75 (44%), Gaps = 19/75 (25%)

Query: 245  PQPGAHP----ACHPLSSVKAAAVAAAAAV--AGGGGLLGPHLLGAPPPPPPPP------ 292
            P+P  HP    A  P S +  A  A   A+  +  GG       GAP PPP PP      
Sbjct: 1335 PRPLVHPLTGKALDPASPLGLALAARERALKESSEGG-------GAPQPPPRPPSPRYEA 1387

Query: 293  PPLAELAGAPHAHHK 307
            PP      +PHAHH+
Sbjct: 1388 PPPTPHHHSPHAHHE 1402


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 73.6 bits (179), Expect = 9e-13
 Identities = 122/493 (24%), Positives = 160/493 (32%), Gaps = 71/493 (14%)

Query: 248 GAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPP--PLAELAGAPHAH 305
           GA PA     +  AA     A  A  GG       G P  P PP P  PL     AP A 
Sbjct: 72  GAGPAAPAEGAPGAAPEPPPAGRARPGG-------GGPQRPGPPSPRRPLVPAGPAPPAA 124

Query: 306 HKRPRFDDDDDS---LQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGV 362
             RP  +    S   +  AA VAA    A A     A  +  A   G G G G   G G 
Sbjct: 125 KLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPG--PGPGP 182

Query: 363 GAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKF-PGCGGLFPHPYTFPAAAAAFSLC 421
           G G G  AG GA    +     + S  +    +     G   L P     P  AA  ++ 
Sbjct: 183 GPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLP----LPKPAAPGTVI 238

Query: 422 HKKEDAGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYP-PFCMFWPPRTPGGLP 480
                 GAAA     A +  A  AP A       PA       P P  +  PP  P G P
Sbjct: 239 QTPPFVGAAAPPAPAAPSPPAAPAPAA-------PAAAPPPPPPAPATLARPPGHPAGPP 291

Query: 481 VPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGP 540
                 PPP                        A+ GG+AG+A A  P    P  V+  P
Sbjct: 292 TAAPAVPPPA----------------------AAQNGGSAGAAPAPAPAAGGPAGVSGQP 329

Query: 541 GSG-----PPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPA 595
           G G     P P       +  +  +PP       +  ++ PA + A+   G    G+ P+
Sbjct: 330 GPGAAAAAPAPGVKAESPKRVVQAAPPAAQ----TLAASGPASTAASMVIGPTMQGALPS 385

Query: 596 GSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTHPH 655
            + VP P         K   G+   S +  P               A+      A   P 
Sbjct: 386 PAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIR-------ATLTPTVLAPRLPQ 438

Query: 656 HHHHPHHHHHHHHPP------QPPSPLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQ 709
              +P +  +   PP           LL++P Q       + H  P     P P  P + 
Sbjct: 439 PPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSA 498

Query: 710 HPHHRGLLSPGGT 722
            P     +   GT
Sbjct: 499 PPVQISTVQAPGT 511



 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 98/381 (25%), Positives = 126/381 (33%), Gaps = 88/381 (23%)

Query: 516 PGGAAGSAEAAPPPG------QPPQVVANGPGSG----PPPPA-------GGAGSRDALF 558
           P GAAG+  AAP  G      +PP      PG G    P PP+        G     A  
Sbjct: 67  PAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKL 126

Query: 559 ESPPGGSGGDC---------SAGSTP-PADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLL 608
             PP GS G C         +AG  P PA     AG  A AA +GP     P P  P   
Sbjct: 127 RPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGP-GPGPG 185

Query: 609 EGRKAGGG------------SYHHSSAFRPVGGKDDAESLAKLHGASAGAPHSA-QTHPH 655
            G+ AG G            + HH++A  P     +    A L      AP +  QT P 
Sbjct: 186 PGKPAGPGAAQTLNGSAALLNSHHAAA--PAVSLVNNGPAALLPLPKPAAPGTVIQTPP- 242

Query: 656 HHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQHPHHRG 715
                           PP+P    PP    P +    PA  PPPPPP P  LA+ P H  
Sbjct: 243 ----------FVGAAAPPAPAAPSPPAAPAPAA----PAAAPPPPPPAPATLARPPGH-- 286

Query: 716 LLSPGGTSCSYPS--EDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEG-----RDPDDDEE 768
              P G   + P+    ++                   P G   + G       P    +
Sbjct: 287 ---PAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVK 343

Query: 769 EDEETEVLLGDPLVGGGRFLQGRGPSEKGSSRDRAPAVAGAFPLGLNSSRLLQEDGKLGD 828
            +    V+   P     + L   GP+   +S    P + GA P                 
Sbjct: 344 AESPKRVVQAAP--PAAQTLAASGPASTAASMVIGPTMQGALP----------------S 385

Query: 829 PGSDLPPPPPPPLAPQKASGG 849
           P +  PP P  P    K + G
Sbjct: 386 PAAVPPPAPGTPTGLPKGAAG 406



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 78/310 (25%), Positives = 94/310 (30%), Gaps = 37/310 (11%)

Query: 231 VKAMFNGGSRKRALPQPGAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPP 290
           V  + NG +    LP+P A            AA   A A         P    A PPPPP
Sbjct: 215 VSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPP 274

Query: 291 PPP-----PLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGA 345
           P P     P    AG P A    P               A    SA AA     AA G A
Sbjct: 275 PAPATLARPPGHPAGPPTAAPAVP-----------PPAAAQNGGSAGAAPAPAPAAGGPA 323

Query: 346 GTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLF 405
           G  G    G   A    G  A +        P +   +      S    +   P   G  
Sbjct: 324 GVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGAL 383

Query: 406 PHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYP 465
           P P   P  A        K  AGA  ++L           P A  SG+        A   
Sbjct: 384 PSPAAVPPPAPGTPTGLPKGAAGAVTQSL--------SRTPTATTSGI-------RATLT 428

Query: 466 PFCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGESPALL---RQAFLDLAEPGGAAGS 522
           P  +   PR P     PT +Q    PP  +     E+  LL   +QA   +     A   
Sbjct: 429 PTVL--APRLPQPPQNPTNIQNFQLPPGMV-LVRSENGQLLMIPQQALAQMQAQAHAQPQ 485

Query: 523 AEAAPPPGQP 532
              AP P  P
Sbjct: 486 TTMAPRPATP 495



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 92/358 (25%), Positives = 118/358 (32%), Gaps = 89/358 (24%)

Query: 245 PQPGAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGA---PPPPPPPPPPLAELAGA 301
           P  G+  +C P+ +  A A     A AG     GP  L A   P P P P P      G 
Sbjct: 129 PPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGK 188

Query: 302 PHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGVG 361
           P                  A   AA +L+ +AA L+   A+  A           V+ V 
Sbjct: 189 P------------------AGPGAAQTLNGSAALLNSHHAAAPA-----------VSLVN 219

Query: 362 VGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSLC 421
            G  A               ++P+P   + G V+Q  P  G   P     P+  AA    
Sbjct: 220 NGPAA---------------LLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAA---- 260

Query: 422 HKKEDAGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPV 481
                          A A  A A P         PA        P  +  PP  P G P 
Sbjct: 261 --------------PAPAAPAAAPPPPP------PA--------PATLARPPGHPAGPPT 292

Query: 482 PTYLQPPP---QPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPG----QPPQ 534
                PPP   Q   + G A   +PA    A +   +PG   G+A AAP PG     P +
Sbjct: 293 AAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVS-GQPG--PGAAAAAPAPGVKAESPKR 349

Query: 535 VVANGPGSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGS 592
           VV   P +     A G  S  A     P   G   S  + PP       G    AAG+
Sbjct: 350 VVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGA 407



 Score = 33.9 bits (76), Expect = 0.78
 Identities = 66/289 (22%), Positives = 87/289 (30%), Gaps = 34/289 (11%)

Query: 579 SVAAAGAGAAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHS--SAFRPVGGKDDAESL 636
           S + AGA  A   +   G+   AP  P     R  GGG       S  RP+     A   
Sbjct: 64  SGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPA 123

Query: 637 AKLHGASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPG--SERHHPA 694
           AKL     G+  S    P                  P P    P +P  P   + R  P 
Sbjct: 124 AKLRPPPEGSAGSCAPVP----------AAAAVAAGPEPAPAGPAKPAGPAALAARAGPG 173

Query: 695 PPPPPPPPPPPPLAQHPHHRGLLSPGGTSCSYPSEDSSE-DEDDEEEEQEVDVEGHKPPE 753
           P P P P P P         G   P G   +     S+            V +  + P  
Sbjct: 174 PGPGPGPGPGP---------GPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAA 224

Query: 754 GEEEEEGRDPDDDEEEDEETEVLLGDPLVGGGRFLQGRGPSEKGSSRDRAPAVAGAFPLG 813
                +   P           V+   P VG         PS   +    APA A   P  
Sbjct: 225 LLPLPKPAAPG---------TVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPP 275

Query: 814 LNSSRLLQEDGKLGDPGSDLPPPPPPPLAPQKASGGGSSSPGSPVHHPS 862
             ++ L +  G    P +  P  PPP  A    S G + +P      P+
Sbjct: 276 APAT-LARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPA 323


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 168/642 (26%), Positives = 194/642 (30%), Gaps = 100/642 (15%)

Query: 271  AGGGGLLGPHLLGAPPPPPPPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLS 330
            AG  G +GP   GAP     P PP       P     +P        +       A    
Sbjct: 569  AGPQGKVGPS--GAPGEDGRPGPP------GPQGARGQPGV------MGFPGPKGANGEP 614

Query: 331  AAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGS 390
              A    +  A G  G  G     G     G    AG     GA GP  +  +P P    
Sbjct: 615  GKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGP- 673

Query: 391  FGGVLQKFPGCGGLFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGAGGAGAAPKAGL 450
                    PG GG  P     P  A A  L   + + G   E       G  G     G 
Sbjct: 674  --------PGEGGK-PGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGT 724

Query: 451  SGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGESPALLRQAF 510
             G   P G              P  P G   P  LQ  P    A G A    P   R   
Sbjct: 725  PGTDGPKGASG-----------PAGPPGAQGPPGLQGMPGERGAAGIA---GPKGDRG-- 768

Query: 511  LDLAEPG-----GAAGSAEAAPPPGQPPQVVANGPGS--GPPPPAGGAGSRDALFE---- 559
             D+ E G     G  G      P G P    ANG     GPP PAG AG+R A  E    
Sbjct: 769  -DVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGET 827

Query: 560  SPPGGSG--GDCSAGSTPPA-DSVAAAGAGAAAAGSGPAG-SRVPAPHHPHLLEGRKAGG 615
             PPG +G  G   A   P A      AG    A   GP G S  P P  P  + G K   
Sbjct: 828  GPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGAR 887

Query: 616  GSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTHPHHHHHPHHHHHHHHPP-QPPS 674
            G+     A     G   A       G++          P     P        PP +   
Sbjct: 888  GAQGPPGA----TGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE 943

Query: 675  PLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQH------PHHRGLLS-PG--GTSCS 725
            P L  P  P     E     P     PP P  LA        P  RG    PG  G S  
Sbjct: 944  PGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGE 1003

Query: 726  YPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEE---------GRDPDDDEEEDEETEVL 776
               + +     D      V   G   P GE   E         GRD     + D      
Sbjct: 1004 PGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGA 1063

Query: 777  LGDPLVGGGRFLQG-RGPSEKGSSRDRAPAVAGAFPLGLNSSRLLQ-------EDGKLGD 828
            +G P   G     G  GP+ K   R  A A     P G   +R +Q       + G+ G+
Sbjct: 1064 VGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGE 1123

Query: 829  PGS------------DLPPPPPPPLAPQKASG-GGSSSPGSP 857
            PG                P PP P   Q ASG  G S P  P
Sbjct: 1124 PGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGP 1165



 Score = 67.0 bits (162), Expect = 8e-11
 Identities = 161/634 (25%), Positives = 199/634 (31%), Gaps = 119/634 (18%)

Query: 265  AAAAAVAGGGGLLGPHLLGAPPPPPPPP--------PPLAELAGAPHAHHKRPR--FDDD 314
            A  A   G  G  GP      P PP PP          +   AGAP     R    F  +
Sbjct: 647  AGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGE 706

Query: 315  DDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGG-------------GAGG------- 354
              S     +     L     +     ASG AG  G              GA G       
Sbjct: 707  RGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGD 766

Query: 355  -GCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFP-GCGGLF------- 405
             G V   G     G   G G  GP   P  P  + G  G V    P G  G         
Sbjct: 767  RGDVGEKGPEGAPGKDGGRGLTGPIG-PPGPAGANGEKGEVGPPGPAGSAGARGAPGERG 825

Query: 406  ----PHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGA----GGAGAAPKAGLSGLFWPA 457
                P P  F     A      K + G A +  G AGA    G +GA    G +G+  P 
Sbjct: 826  ETGPPGPAGFAGPPGADGQPGAKGEQGEAGQK-GDAGAPGPQGPSGAPGPQGPTGVTGPK 884

Query: 458  GRKDAFYPPFCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPG 517
            G + A  PP    +P     G   P      P PP   G +  + P   + A  D   PG
Sbjct: 885  GARGAQGPPGATGFP--GAAGRVGPPGSNGNPGPPGPPGPSGKDGP---KGARGDSGPPG 939

Query: 518  --GAAGSAEAAPPPGQPPQVVANGP--GSGPPPPAGGAGSRDALFESPPGGSGGDCSAGS 573
              G  G    A PPG+  +   +GP    GPP P G AG R  +    PG  G     G 
Sbjct: 940  RAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIV--GLPGQRGERGFPGL 997

Query: 574  TPPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDA 633
              P+      GA  A+   GP     P P  P  L G     G      A  P  G+D A
Sbjct: 998  PGPSGEPGKQGAPGASGDRGP-----PGPVGPPGLTGPAGEPGREGSPGADGP-PGRDGA 1051

Query: 634  ESLAKLHG--ASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSERH 691
              +    G   + GAP +                   PP  P P      Q D   +   
Sbjct: 1052 AGVKGDRGETGAVGAPGAP-----------------GPPGSPGPAGPTGKQGDRGEAGAQ 1094

Query: 692  HPAPPPPPPPPPPPPLAQHPHHRGLLSPGGTSCSYPSEDSSEDEDDEEEEQEVDVEGHKP 751
             P  P  P              RG+  P G            D+ +  E  E  ++GH+ 
Sbjct: 1095 GPMGPSGPAGA-----------RGIQGPQG---------PRGDKGEAGEPGERGLKGHRG 1134

Query: 752  PEGEEEEEG-RDPDDDEEEDEETEVLLGDPLVGGGRFLQGR-GPSEKGSSRDRAPAVAGA 809
              G +   G   P  D+          G     G R   G  GPS K  +      +   
Sbjct: 1135 FTGLQGLPGPPGPSGDQGAS-------GPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPP 1187

Query: 810  FPLGLNSSRLLQEDGKLGDPGSDLPPPPPPPLAP 843
             P G +      E G  G PG+  PP PP P  P
Sbjct: 1188 GPRGRSG-----ETGPAGPPGNPGPPGPPGPPGP 1216



 Score = 57.4 bits (137), Expect = 7e-08
 Identities = 148/590 (25%), Positives = 177/590 (30%), Gaps = 120/590 (20%)

Query: 339 AAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIP-------------- 384
           A   G  G  GG    G     G     GA    GA+GPR  P  P              
Sbjct: 353 AGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGT 412

Query: 385 --VP-SKGSFGGVLQKFPGCGGL--FPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGA 439
             +P +KGS G      PG  G   FP P   P    A      K   G    A      
Sbjct: 413 DGIPGAKGSAGA-----PGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQ 467

Query: 440 GGAGAAPKAGLSGLFWPA---GRKDAFYPPFCM--FWPPRTPG-----GLPVPTYLQPPP 489
           G  G    AG  G   PA   G++ A   P  +    PP   G     G P    L  P 
Sbjct: 468 GPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPK 527

Query: 490 QPPSALGCALGESPALLRQAFLDLAEPG-----GAAGSAEAAPPPGQPPQVVANG-PGS- 542
             P   G +    P   + A  D   PG     GA G        G   +V  +G PG  
Sbjct: 528 GAPGERGPSGLAGP---KGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGED 584

Query: 543 ---GPPPPAGGAGSRDAL-FESPPGGSGGDCSAG--STPPADSV-------AAAGAGAAA 589
              GPP P G  G    + F  P G +G    AG    P A  +          GA    
Sbjct: 585 GRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPP 644

Query: 590 AGSGPAGSR----VPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAG 645
             +GPAG R     P P     L G     G           GGK   + +       AG
Sbjct: 645 GPAGPAGERGEQGAPGPSGFQGLPGPPGPPGE----------GGKPGDQGVP----GEAG 690

Query: 646 APHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSE--RHHPAPPPPPPPPP 703
           AP                       Q P  L      P  PG++  +    P  PP    
Sbjct: 691 APGLVGPRGERGFPGERGSPGAQGLQGPRGL------PGTPGTDGPKGASGPAGPPGAQG 744

Query: 704 PPPLAQHPHHRGLLSPGGTSCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEG--- 760
           PP L   P  RG     G     P  D  +              G K PEG   ++G   
Sbjct: 745 PPGLQGMPGERGAAGIAG-----PKGDRGD-------------VGEKGPEGAPGKDGGRG 786

Query: 761 -----RDPDDDEEEDEETEVLLGDPLVGGGRFLQGRGPSEKGSSRDRAPA------VAGA 809
                  P       E+ EV  G P   G    +G  P E+G +    PA       A  
Sbjct: 787 LTGPIGPPGPAGANGEKGEV--GPPGPAGSAGARG-APGERGETGPPGPAGFAGPPGADG 843

Query: 810 FPLGLNSSRLLQEDGKLGDPGSDLPPPPPPPLAPQKASG--GGSSSPGSP 857
            P          + G  G PG   P   P P  P   +G  G   + G P
Sbjct: 844 QPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPP 893



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 158/654 (24%), Positives = 193/654 (29%), Gaps = 101/654 (15%)

Query: 270  VAGGGGLLG-PHLLGAPPPPPPPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAAS 328
            + G  G  G P + GAP  P P  PP  + A  P      P+    +  +  A       
Sbjct: 415  IPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLG----PKGQTGEPGI--AGFKGEQG 468

Query: 329  LSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYP-----VI 383
                        A G AG  G     G   GVG     G     GA G R +P       
Sbjct: 469  PKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVG---PIGPPGERGAPGNRGFPGQDGLAG 525

Query: 384  PVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGAGGAG 443
            P  + G  G      P      P     P    A  L  +  DAG   + +G +GA G  
Sbjct: 526  PKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGK-VGPSGAPGED 584

Query: 444  AAPKAGLSGLFWPAGRKDAFYPPFCMFWP-----------------PRTPG--GLP---V 481
              P         P G + A   P  M +P                 P  PG  GLP    
Sbjct: 585  GRP--------GPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDG 636

Query: 482  PTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANG-- 539
             T    PP P    G   GE  A     F  L  P G  G        G P +  A G  
Sbjct: 637  ETGAAGPPGPAGPAG-ERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLV 695

Query: 540  --------PGSGPPPPAGGAGSRDAL-----FESPPGGSGGDCSAGSTPPADSVAAAGAG 586
                    PG    P A G      L      + P G SG     G+  P       G  
Sbjct: 696  GPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGER 755

Query: 587  AAAAGSGPAGSRVPAPHH-PHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAG 645
             AA  +GP G R       P    G+  G G         P G   +   +     A + 
Sbjct: 756  GAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSA 815

Query: 646  APHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPD-EPGSE-------RHHPAPPP 697
                A                  PP P       PP  D +PG++       +   A  P
Sbjct: 816  GARGAP----------GERGETGPPGPAG--FAGPPGADGQPGAKGEQGEAGQKGDAGAP 863

Query: 698  PPPPPPPPPLAQHPHHRGLLSPGGTSCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEE 757
             P  P   P  Q P   G+  P G   +     ++               G+  P G   
Sbjct: 864  GPQGPSGAPGPQGP--TGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG 921

Query: 758  EEGRDPDDDEEEDEETEVLLGDPLVGGGRFLQGRG--PSEKGSSRDRAPAVAGA--FPLG 813
              G+D       D       G P   G   LQG    P EKG   D  P+ A     P G
Sbjct: 922  PSGKDGPKGARGDS------GPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQG 975

Query: 814  LNSSR----LLQEDGKLGDPGSDLPPPPPPPLAPQKASGGGSSSPGSPVHHPSL 863
            L   R    L  + G+ G PG  LP P   P         G   P  PV  P L
Sbjct: 976  LAGQRGIVGLPGQRGERGFPG--LPGPSGEPGKQGAPGASGDRGPPGPVGPPGL 1027



 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 144/633 (22%), Positives = 178/633 (28%), Gaps = 90/633 (14%)

Query: 279 PHLLGAPPPPPPPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSV 338
           P   G P PP PP PP     G   A      FD+             A L      +  
Sbjct: 155 PGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEK---------AGGAQLGVMQGPMGP 205

Query: 339 AAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIP-------VPSKGSF 391
               G  G  G     G     G     G     G +GP   P  P        P K   
Sbjct: 206 MGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGE 265

Query: 392 GGV-----LQKFPGCGGL--------FPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAG 438
            G       + FPG  GL        +P        A A  +   K ++G+  E      
Sbjct: 266 RGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGV---KGESGSPGENGSPGP 322

Query: 439 AGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQPPPQPPSALGCA 498
            G  G   + G +G    AG +     P         P G P P      P  P A G A
Sbjct: 323 MGPRGLPGERGRTGPAGAAGARGNDGQP--------GPAGPPGPVGPAGGPGFPGAPG-A 373

Query: 499 LGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQP-------PQVVANGPGSGPPPPAGGA 551
            GE            A P GA G   A  P G+P       P   +  PG+   P A G+
Sbjct: 374 KGE------------AGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGS 421

Query: 552 GSRDAL-----FESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPA-PHHP 605
                +     F  P G  G   + G   P       G        GP G   PA P   
Sbjct: 422 AGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGA 481

Query: 606 HLLEGRKAGGGSYHHSSAFRPVG-----------GKDDAESLAKLHGA-------SAGAP 647
               G +   G+        P+G           G    + LA   GA           P
Sbjct: 482 PGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGP 541

Query: 648 HSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPL 707
             A   P     P          +P          P     E   P PP P      P +
Sbjct: 542 KGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGV 601

Query: 708 AQHPHHRGLLSPGGTSCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPDDDE 767
              P  +G     G +       +        ++ E    G   P G   E G       
Sbjct: 602 MGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGP 661

Query: 768 EEDEETEVLLGDPLVGGGRFLQGRGPSEKGSSRDRAPAVAGAFP--LGLNSSRLLQ-EDG 824
              +      G P  GG    QG  P E G+     P     FP   G   ++ LQ   G
Sbjct: 662 SGFQGLPGPPGPPGEGGKPGDQG-VPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRG 720

Query: 825 KLGDPGSDLPPPPPPPLAPQKASG--GGSSSPG 855
             G PG+D P     P  P  A G  G    PG
Sbjct: 721 LPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPG 753



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 96/402 (23%), Positives = 119/402 (29%), Gaps = 65/402 (16%)

Query: 255  PLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPPPLAELAGAPHAHHKRPRFDDD 314
            P  +  A     A    G  G +GP      P PP PP P  +              D  
Sbjct: 883  PKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGK--------------DGP 928

Query: 315  DDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGA 374
              +  ++     A               G  G  G     G     G+    G     G 
Sbjct: 929  KGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQ 988

Query: 375  KGPRSYPVIPVPSKGSFGGVLQKFPGCGGLF--PHPYTFPAAAAAFSLCHKKEDAGAAAE 432
            +G R +P +P PS G  G   Q  PG  G    P P   P               G A E
Sbjct: 989  RGERGFPGLPGPS-GEPG--KQGAPGASGDRGPPGPVGPPGL------------TGPAGE 1033

Query: 433  ALGGAGAGGAGAAP-KAGLSGLFWPAGRKDAFYPPFCMFWPPRTPG--------GLPVPT 483
              G  G+ GA   P + G +G+    G   A   P     PP +PG        G     
Sbjct: 1034 P-GREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAP-GPPGSPGPAGPTGKQGDRGEA 1091

Query: 484  YLQPPPQPPSALGCALGESPALLRQAFLDLAEPG--------GAAGSAEAAPPPGQPPQV 535
              Q P  P    G    + P   R    +  EPG        G  G      PPG     
Sbjct: 1092 GAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQ 1151

Query: 536  VANGPGS-----GPPPPAGGAGSRDAL-FESPPGGSGGDCSAGSTPPADSVAAAGAGAAA 589
             A+GP       GPP P G +G   A     P G  G    +G T PA      G     
Sbjct: 1152 GASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPP 1211

Query: 590  AGSGPA---------GSRVPAPHHPHLLEGRKAGGGSYHHSS 622
               GP          G R   P     +   +A GG   H +
Sbjct: 1212 GPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAAGGLRQHDA 1253



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 85/350 (24%), Positives = 110/350 (31%), Gaps = 74/350 (21%)

Query: 512 DLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPPPAGGAGSRDALFESPPGGSGGDCSA 571
           DLA   G  G       PG    +V      GP  PAG  G        P G  G     
Sbjct: 92  DLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQG--------PRGDRGDKGEK 143

Query: 572 GSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKD 631
           G+  P       G        GP G     P  P L       GG++    A +  GG D
Sbjct: 144 GAPGPRGRDGEPGTPGNPGPPGPPG----PPGPPGL-------GGNF----AAQMAGGFD 188

Query: 632 DAESLAKLHGASAG--APHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSE 689
           +    A+L G   G   P   +  P     P       +P +P  P +  P  P      
Sbjct: 189 EKAGGAQL-GVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGP------ 241

Query: 690 RHHPAPPPPPPPPPPPPLAQHPHHRGLLSPGGT--SCSYPSEDSSEDEDDEEEEQEVDVE 747
                PP PP  P     A  P   G   P G   +  +P                  V+
Sbjct: 242 ---RGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLP-----------GVK 287

Query: 748 GHKPPEGEEEEEGRDPDDDEEEDEETEVLLGDPLVGGGRFLQGRGPSEKGSSRDRAPAVA 807
           GH+   G +  +G       + +  +    G P   G R L    P E+G +        
Sbjct: 288 GHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGL----PGERGRTG------- 336

Query: 808 GAFPLGLNSSRLLQEDGKLGDPGSDLPPPPPPPLAPQKASGGGSSSPGSP 857
              P G   +R     G  G PG   P  PP P+ P     GG   PG+P
Sbjct: 337 ---PAGAAGAR-----GNDGQPG---PAGPPGPVGP----AGGPGFPGAP 371


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score = 72.8 bits (177), Expect = 2e-12
 Identities = 168/642 (26%), Positives = 194/642 (30%), Gaps = 100/642 (15%)

Query: 271  AGGGGLLGPHLLGAPPPPPPPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLS 330
            AG  G +GP   GAP     P PP       P     +P        +       A    
Sbjct: 500  AGPQGKVGPS--GAPGEDGRPGPP------GPQGARGQPGV------MGFPGPKGANGEP 545

Query: 331  AAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGS 390
              A    +  A G  G  G     G     G    AG     GA GP  +  +P P    
Sbjct: 546  GKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGP- 604

Query: 391  FGGVLQKFPGCGGLFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGAGGAGAAPKAGL 450
                    PG GG  P     P  A A  L   + + G   E       G  G     G 
Sbjct: 605  --------PGEGGK-PGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGT 655

Query: 451  SGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGESPALLRQAF 510
             G   P G              P  P G   P  LQ  P    A G A    P   R   
Sbjct: 656  PGTDGPKGASG-----------PAGPPGAQGPPGLQGMPGERGAAGIA---GPKGDRG-- 699

Query: 511  LDLAEPG-----GAAGSAEAAPPPGQPPQVVANGPGS--GPPPPAGGAGSRDALFE---- 559
             D+ E G     G  G      P G P    ANG     GPP PAG AG+R A  E    
Sbjct: 700  -DVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGET 758

Query: 560  SPPGGSG--GDCSAGSTPPA-DSVAAAGAGAAAAGSGPAG-SRVPAPHHPHLLEGRKAGG 615
             PPG +G  G   A   P A      AG    A   GP G S  P P  P  + G K   
Sbjct: 759  GPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGAR 818

Query: 616  GSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTHPHHHHHPHHHHHHHHPP-QPPS 674
            G+     A     G   A       G++          P     P        PP +   
Sbjct: 819  GAQGPPGA----TGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE 874

Query: 675  PLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQH------PHHRGLLS-PG--GTSCS 725
            P L  P  P     E     P     PP P  LA        P  RG    PG  G S  
Sbjct: 875  PGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGE 934

Query: 726  YPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEE---------GRDPDDDEEEDEETEVL 776
               + +     D      V   G   P GE   E         GRD     + D      
Sbjct: 935  PGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGA 994

Query: 777  LGDPLVGGGRFLQG-RGPSEKGSSRDRAPAVAGAFPLGLNSSRLLQ-------EDGKLGD 828
            +G P   G     G  GP+ K   R  A A     P G   +R +Q       + G+ G+
Sbjct: 995  VGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGE 1054

Query: 829  PGS------------DLPPPPPPPLAPQKASG-GGSSSPGSP 857
            PG                P PP P   Q ASG  G S P  P
Sbjct: 1055 PGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGP 1096



 Score = 67.0 bits (162), Expect = 8e-11
 Identities = 161/634 (25%), Positives = 199/634 (31%), Gaps = 119/634 (18%)

Query: 265  AAAAAVAGGGGLLGPHLLGAPPPPPPPP--------PPLAELAGAPHAHHKRPR--FDDD 314
            A  A   G  G  GP      P PP PP          +   AGAP     R    F  +
Sbjct: 578  AGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGE 637

Query: 315  DDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGG-------------GAGG------- 354
              S     +     L     +     ASG AG  G              GA G       
Sbjct: 638  RGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGD 697

Query: 355  -GCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFP-GCGGLF------- 405
             G V   G     G   G G  GP   P  P  + G  G V    P G  G         
Sbjct: 698  RGDVGEKGPEGAPGKDGGRGLTGPIG-PPGPAGANGEKGEVGPPGPAGSAGARGAPGERG 756

Query: 406  ----PHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGA----GGAGAAPKAGLSGLFWPA 457
                P P  F     A      K + G A +  G AGA    G +GA    G +G+  P 
Sbjct: 757  ETGPPGPAGFAGPPGADGQPGAKGEQGEAGQK-GDAGAPGPQGPSGAPGPQGPTGVTGPK 815

Query: 458  GRKDAFYPPFCMFWPPRTPGGLPVPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPG 517
            G + A  PP    +P     G   P      P PP   G +  + P   + A  D   PG
Sbjct: 816  GARGAQGPPGATGFP--GAAGRVGPPGSNGNPGPPGPPGPSGKDGP---KGARGDSGPPG 870

Query: 518  --GAAGSAEAAPPPGQPPQVVANGP--GSGPPPPAGGAGSRDALFESPPGGSGGDCSAGS 573
              G  G    A PPG+  +   +GP    GPP P G AG R  +    PG  G     G 
Sbjct: 871  RAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIV--GLPGQRGERGFPGL 928

Query: 574  TPPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDA 633
              P+      GA  A+   GP     P P  P  L G     G      A  P  G+D A
Sbjct: 929  PGPSGEPGKQGAPGASGDRGP-----PGPVGPPGLTGPAGEPGREGSPGADGP-PGRDGA 982

Query: 634  ESLAKLHG--ASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSERH 691
              +    G   + GAP +                   PP  P P      Q D   +   
Sbjct: 983  AGVKGDRGETGAVGAPGAP-----------------GPPGSPGPAGPTGKQGDRGEAGAQ 1025

Query: 692  HPAPPPPPPPPPPPPLAQHPHHRGLLSPGGTSCSYPSEDSSEDEDDEEEEQEVDVEGHKP 751
             P  P  P              RG+  P G            D+ +  E  E  ++GH+ 
Sbjct: 1026 GPMGPSGPAGA-----------RGIQGPQG---------PRGDKGEAGEPGERGLKGHRG 1065

Query: 752  PEGEEEEEG-RDPDDDEEEDEETEVLLGDPLVGGGRFLQGR-GPSEKGSSRDRAPAVAGA 809
              G +   G   P  D+          G     G R   G  GPS K  +      +   
Sbjct: 1066 FTGLQGLPGPPGPSGDQGAS-------GPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPP 1118

Query: 810  FPLGLNSSRLLQEDGKLGDPGSDLPPPPPPPLAP 843
             P G +      E G  G PG+  PP PP P  P
Sbjct: 1119 GPRGRSG-----ETGPAGPPGNPGPPGPPGPPGP 1147



 Score = 57.4 bits (137), Expect = 7e-08
 Identities = 148/590 (25%), Positives = 177/590 (30%), Gaps = 120/590 (20%)

Query: 339 AAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIP-------------- 384
           A   G  G  GG    G     G     GA    GA+GPR  P  P              
Sbjct: 284 AGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGT 343

Query: 385 --VP-SKGSFGGVLQKFPGCGGL--FPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGA 439
             +P +KGS G      PG  G   FP P   P    A      K   G    A      
Sbjct: 344 DGIPGAKGSAGA-----PGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQ 398

Query: 440 GGAGAAPKAGLSGLFWPA---GRKDAFYPPFCM--FWPPRTPG-----GLPVPTYLQPPP 489
           G  G    AG  G   PA   G++ A   P  +    PP   G     G P    L  P 
Sbjct: 399 GPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPK 458

Query: 490 QPPSALGCALGESPALLRQAFLDLAEPG-----GAAGSAEAAPPPGQPPQVVANG-PGS- 542
             P   G +    P   + A  D   PG     GA G        G   +V  +G PG  
Sbjct: 459 GAPGERGPSGLAGP---KGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGED 515

Query: 543 ---GPPPPAGGAGSRDAL-FESPPGGSGGDCSAG--STPPADSV-------AAAGAGAAA 589
              GPP P G  G    + F  P G +G    AG    P A  +          GA    
Sbjct: 516 GRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPP 575

Query: 590 AGSGPAGSR----VPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAG 645
             +GPAG R     P P     L G     G           GGK   + +       AG
Sbjct: 576 GPAGPAGERGEQGAPGPSGFQGLPGPPGPPGE----------GGKPGDQGVP----GEAG 621

Query: 646 APHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSE--RHHPAPPPPPPPPP 703
           AP                       Q P  L      P  PG++  +    P  PP    
Sbjct: 622 APGLVGPRGERGFPGERGSPGAQGLQGPRGL------PGTPGTDGPKGASGPAGPPGAQG 675

Query: 704 PPPLAQHPHHRGLLSPGGTSCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEG--- 760
           PP L   P  RG     G     P  D  +              G K PEG   ++G   
Sbjct: 676 PPGLQGMPGERGAAGIAG-----PKGDRGD-------------VGEKGPEGAPGKDGGRG 717

Query: 761 -----RDPDDDEEEDEETEVLLGDPLVGGGRFLQGRGPSEKGSSRDRAPA------VAGA 809
                  P       E+ EV  G P   G    +G  P E+G +    PA       A  
Sbjct: 718 LTGPIGPPGPAGANGEKGEV--GPPGPAGSAGARG-APGERGETGPPGPAGFAGPPGADG 774

Query: 810 FPLGLNSSRLLQEDGKLGDPGSDLPPPPPPPLAPQKASG--GGSSSPGSP 857
            P          + G  G PG   P   P P  P   +G  G   + G P
Sbjct: 775 QPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPP 824



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 158/654 (24%), Positives = 193/654 (29%), Gaps = 101/654 (15%)

Query: 270 VAGGGGLLG-PHLLGAPPPPPPPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAAS 328
           + G  G  G P + GAP  P P  PP  + A  P      P+    +  +  A       
Sbjct: 346 IPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLG----PKGQTGEPGI--AGFKGEQG 399

Query: 329 LSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYP-----VI 383
                       A G AG  G     G   GVG     G     GA G R +P       
Sbjct: 400 PKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVG---PIGPPGERGAPGNRGFPGQDGLAG 456

Query: 384 PVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGAGGAG 443
           P  + G  G      P      P     P    A  L  +  DAG   + +G +GA G  
Sbjct: 457 PKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGK-VGPSGAPGED 515

Query: 444 AAPKAGLSGLFWPAGRKDAFYPPFCMFWP-----------------PRTPG--GLP---V 481
             P         P G + A   P  M +P                 P  PG  GLP    
Sbjct: 516 GRP--------GPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDG 567

Query: 482 PTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANG-- 539
            T    PP P    G   GE  A     F  L  P G  G        G P +  A G  
Sbjct: 568 ETGAAGPPGPAGPAG-ERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLV 626

Query: 540 --------PGSGPPPPAGGAGSRDAL-----FESPPGGSGGDCSAGSTPPADSVAAAGAG 586
                   PG    P A G      L      + P G SG     G+  P       G  
Sbjct: 627 GPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGER 686

Query: 587 AAAAGSGPAGSRVPAPHH-PHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAG 645
            AA  +GP G R       P    G+  G G         P G   +   +     A + 
Sbjct: 687 GAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSA 746

Query: 646 APHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPD-EPGSE-------RHHPAPPP 697
               A                  PP P       PP  D +PG++       +   A  P
Sbjct: 747 GARGAP----------GERGETGPPGPAG--FAGPPGADGQPGAKGEQGEAGQKGDAGAP 794

Query: 698 PPPPPPPPPLAQHPHHRGLLSPGGTSCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEE 757
            P  P   P  Q P   G+  P G   +     ++               G+  P G   
Sbjct: 795 GPQGPSGAPGPQGP--TGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPG 852

Query: 758 EEGRDPDDDEEEDEETEVLLGDPLVGGGRFLQGRG--PSEKGSSRDRAPAVAGA--FPLG 813
             G+D       D       G P   G   LQG    P EKG   D  P+ A     P G
Sbjct: 853 PSGKDGPKGARGDS------GPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQG 906

Query: 814 LNSSR----LLQEDGKLGDPGSDLPPPPPPPLAPQKASGGGSSSPGSPVHHPSL 863
           L   R    L  + G+ G PG  LP P   P         G   P  PV  P L
Sbjct: 907 LAGQRGIVGLPGQRGERGFPG--LPGPSGEPGKQGAPGASGDRGPPGPVGPPGL 958



 Score = 50.8 bits (120), Expect = 6e-06
 Identities = 144/633 (22%), Positives = 178/633 (28%), Gaps = 90/633 (14%)

Query: 279 PHLLGAPPPPPPPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSV 338
           P   G P PP PP PP     G   A      FD+             A L      +  
Sbjct: 86  PGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEK---------AGGAQLGVMQGPMGP 136

Query: 339 AAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIP-------VPSKGSF 391
               G  G  G     G     G     G     G +GP   P  P        P K   
Sbjct: 137 MGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGE 196

Query: 392 GGV-----LQKFPGCGGL--------FPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAG 438
            G       + FPG  GL        +P        A A  +   K ++G+  E      
Sbjct: 197 RGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGV---KGESGSPGENGSPGP 253

Query: 439 AGGAGAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQPPPQPPSALGCA 498
            G  G   + G +G    AG +     P         P G P P      P  P A G A
Sbjct: 254 MGPRGLPGERGRTGPAGAAGARGNDGQP--------GPAGPPGPVGPAGGPGFPGAPG-A 304

Query: 499 LGESPALLRQAFLDLAEPGGAAGSAEAAPPPGQP-------PQVVANGPGSGPPPPAGGA 551
            GE            A P GA G   A  P G+P       P   +  PG+   P A G+
Sbjct: 305 KGE------------AGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGS 352

Query: 552 GSRDAL-----FESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPA-PHHP 605
                +     F  P G  G   + G   P       G        GP G   PA P   
Sbjct: 353 AGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGA 412

Query: 606 HLLEGRKAGGGSYHHSSAFRPVG-----------GKDDAESLAKLHGA-------SAGAP 647
               G +   G+        P+G           G    + LA   GA           P
Sbjct: 413 PGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGP 472

Query: 648 HSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPL 707
             A   P     P          +P          P     E   P PP P      P +
Sbjct: 473 KGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGV 532

Query: 708 AQHPHHRGLLSPGGTSCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPDDDE 767
              P  +G     G +       +        ++ E    G   P G   E G       
Sbjct: 533 MGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGP 592

Query: 768 EEDEETEVLLGDPLVGGGRFLQGRGPSEKGSSRDRAPAVAGAFP--LGLNSSRLLQ-EDG 824
              +      G P  GG    QG  P E G+     P     FP   G   ++ LQ   G
Sbjct: 593 SGFQGLPGPPGPPGEGGKPGDQG-VPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRG 651

Query: 825 KLGDPGSDLPPPPPPPLAPQKASG--GGSSSPG 855
             G PG+D P     P  P  A G  G    PG
Sbjct: 652 LPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPG 684



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 96/402 (23%), Positives = 119/402 (29%), Gaps = 65/402 (16%)

Query: 255  PLSSVKAAAVAAAAAVAGGGGLLGPHLLGAPPPPPPPPPPLAELAGAPHAHHKRPRFDDD 314
            P  +  A     A    G  G +GP      P PP PP P  +              D  
Sbjct: 814  PKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGK--------------DGP 859

Query: 315  DDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGA 374
              +  ++     A               G  G  G     G     G+    G     G 
Sbjct: 860  KGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQ 919

Query: 375  KGPRSYPVIPVPSKGSFGGVLQKFPGCGGLF--PHPYTFPAAAAAFSLCHKKEDAGAAAE 432
            +G R +P +P PS G  G   Q  PG  G    P P   P               G A E
Sbjct: 920  RGERGFPGLPGPS-GEPG--KQGAPGASGDRGPPGPVGPPGL------------TGPAGE 964

Query: 433  ALGGAGAGGAGAAP-KAGLSGLFWPAGRKDAFYPPFCMFWPPRTPG--------GLPVPT 483
              G  G+ GA   P + G +G+    G   A   P     PP +PG        G     
Sbjct: 965  P-GREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAP-GPPGSPGPAGPTGKQGDRGEA 1022

Query: 484  YLQPPPQPPSALGCALGESPALLRQAFLDLAEPG--------GAAGSAEAAPPPGQPPQV 535
              Q P  P    G    + P   R    +  EPG        G  G      PPG     
Sbjct: 1023 GAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQ 1082

Query: 536  VANGPGS-----GPPPPAGGAGSRDAL-FESPPGGSGGDCSAGSTPPADSVAAAGAGAAA 589
             A+GP       GPP P G +G   A     P G  G    +G T PA      G     
Sbjct: 1083 GASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPP 1142

Query: 590  AGSGPA---------GSRVPAPHHPHLLEGRKAGGGSYHHSS 622
               GP          G R   P     +   +A GG   H +
Sbjct: 1143 GPPGPGIDMSAFAGLGPREKGPDPLQYMRADQAAGGLRQHDA 1184



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 94/365 (25%), Positives = 119/365 (32%), Gaps = 92/365 (25%)

Query: 504 ALLRQAFLDLAEPGGAAGSAEAAPPPGQPPQVVANGPGSGPPPPAGGAGSRDALFESPPG 563
           A+LR    D+ +PG      E    PG    +V  GP  GPP P G AG      + P G
Sbjct: 19  AVLRCQGQDVRQPGPKGQKGE----PGDIKDIV--GP-KGPPGPQGPAGE-----QGPRG 66

Query: 564 GSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSA 623
             G     G+  P       G        GP G     P  P L       GG++    A
Sbjct: 67  DRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGP----PGPPGL-------GGNF----A 111

Query: 624 FRPVGGKDDAESLAKLHGASAGAPHSAQTHPHHHHHPHHHHHHHHPPQP-----PSPLLL 678
            +  GG D+     K  GA  G              P        PP P     P     
Sbjct: 112 AQMAGGFDE-----KAGGAQLGVMQG----------PMGPMGPRGPPGPAGAPGPQGFQG 156

Query: 679 LPPQPDEPGSERHHPAPPPPPPPPPPPP----LAQHPHHRGLLSPGGT--SCSYPSEDSS 732
            P +P EPG     P  P  PP PP  P     A  P   G   P G   +  +P     
Sbjct: 157 NPGEPGEPGVS--GPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGL 214

Query: 733 EDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPDDDEEEDEETEVLLGDPLVGGGRFLQGRG 792
                        V+GH+   G +  +G       + +  +    G P   G R L    
Sbjct: 215 P-----------GVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGL---- 259

Query: 793 PSEKGSSRDRAPAVAGAFPLGLNSSRLLQEDGKLGDPGSDLPPPPPPPLAPQKASGGGSS 852
           P E+G +           P G   +R     G  G PG   P  PP P+ P     GG  
Sbjct: 260 PGERGRTG----------PAGAAGAR-----GNDGQPG---PAGPPGPVGP----AGGPG 297

Query: 853 SPGSP 857
            PG+P
Sbjct: 298 FPGAP 302



 Score = 37.0 bits (84), Expect = 0.092
 Identities = 115/476 (24%), Positives = 146/476 (30%), Gaps = 99/476 (20%)

Query: 423 KKEDAGAAAEALGGAGAGGA-GAAPKAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPV 481
           +K + G   + +G  G  G  G A + G  G     G K A   P      P TPG  P 
Sbjct: 36  QKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGA-PGPRGRDGEPGTPGN-PG 93

Query: 482 PTYLQPPPQPPSALGC-----------ALGESPALLRQAFLDLAEPGGAAGSAEAAPP-- 528
           P     PP PP   G              G +   + Q  +    P G  G A A  P  
Sbjct: 94  PPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQG 153

Query: 529 ----PGQPPQVVANGPGSGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAG 584
               PG+P +   +GP  GP  P G           PPG  G D  AG    A      G
Sbjct: 154 FQGNPGEPGEPGVSGP-MGPRGPPG-----------PPGKPGDDGEAGKPGKAGERGPPG 201

Query: 585 AGAAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHG--A 642
              A    G  G           L G K            R   G D A+  A   G   
Sbjct: 202 PQGARGFPGTPG-----------LPGVK----------GHRGYPGLDGAKGEAGAPGVKG 240

Query: 643 SAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQ----PDEPGSERHHPAPPPP 698
            +G+P                   +  P P  P  L   +    P      R +   P P
Sbjct: 241 ESGSP-----------------GENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGP 283

Query: 699 PPPPPPPPLAQHPHHRGLLSPGGTSCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEE 758
             PP P   A  P   G  +PG    + P+  +   E  +    E    G   P G    
Sbjct: 284 AGPPGPVGPAGGPGFPG--APGAKGEAGPT-GARGPEGAQGPRGEPGTPGSPGPAGASGN 340

Query: 759 EGRDPDDDEEEDEETEVLLGDPLVGGGRFLQG----RGP-SEKGSSRDRAPAVAGAFPLG 813
            G D     +       + G P   G R   G     GP   KG + +  P +AG     
Sbjct: 341 PGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGE--PGIAG----- 393

Query: 814 LNSSRLLQEDGKLGDPGSDLPPPPPPPLAPQKASGGGSSSPG--SPVHHPSLEEQP 867
                   E G  G+PG   P   P P A ++   G    PG   P+  P     P
Sbjct: 394 -----FKGEQGPKGEPGPAGPQGAPGP-AGEEGKRGARGEPGGVGPIGPPGERGAP 443


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 151/548 (27%), Positives = 175/548 (31%), Gaps = 85/548 (15%)

Query: 343  GGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGV----LQKF 398
            G  G  G     G   G G     G     G +GP   P  P   KG  G      LQ  
Sbjct: 585  GNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPG-PTGPGGDKGDTGPPGPQGLQGL 643

Query: 399  PGCGGLFPHPYTFPAA------AAAFSLCHKKEDAGAAAEA--LGGAGA----GGAGAAP 446
            PG GG  P     P        A A      K DAGA  E    G AGA    GGAG   
Sbjct: 644  PGTGGP-PGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPG 702

Query: 447  KAGLSGLFWPAGRKDAFYPPFCMFWPPRTPG-GLPVPTYLQPPPQPPSALGCALGESPAL 505
              G  G   P G   A   P     P    G G P P   +  P  P A G    + P  
Sbjct: 703  PEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGP-- 760

Query: 506  LRQAFLDLAEPG--GAAGSAEAAPPPGQPPQVVANG-PG----SGPPPPAGGAGSRDALF 558
             R     +  PG  G  G       PG P      G PG    +GPP PAG  G+     
Sbjct: 761  -RGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNG 819

Query: 559  ESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSY 618
            E  PGG G   + G          AG      GSGPAG   P P       G   G G+ 
Sbjct: 820  E--PGGKGERGAPGEKGEGGPPGVAGP---PGGSGPAGP--PGPQGVKGERGSPGGPGAA 872

Query: 619  HHSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLL 678
                A R + G   +       G S          P  +              P SP + 
Sbjct: 873  GFPGA-RGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGN-----------TGAPGSPGVS 920

Query: 679  LPP----QPDEPGSERHHPAPPPPPPPPPPPPLAQHPHHRGLLSPGGTSCSYPSEDSSED 734
             P     QP E GS    P    PP  P P  +A     RGL  P G      S      
Sbjct: 921  GPKGDAGQPGEKGS----PGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGV 976

Query: 735  EDDEEEEQEVDVEGHKPPEGEEEEEGRDPDDDEEEDEETEVLLGDPLVGGGRFLQGRGPS 794
            + +  +     + G + P G +   G      E   +      G+P   G   L GR  S
Sbjct: 977  KGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRD------GNP---GSDGLPGRDGS 1027

Query: 795  EKGSSRDRAPAVAGAFPLGLNSSRLLQEDGKLGDPGSDLPPPPPPPLAPQKASGG-GSSS 853
              G   DR                   E+G  G PG+   P PP P+ P   SG  G S 
Sbjct: 1028 PGGKG-DRG------------------ENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESG 1068

Query: 854  PGSPVHHP 861
            P  P   P
Sbjct: 1069 PAGPAGAP 1076



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 160/630 (25%), Positives = 194/630 (30%), Gaps = 118/630 (18%)

Query: 272  GGGGLLGPHLLGAPPPP---PPPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAAS 328
            G  GL G    G PP     P  P P  + AGAP A    P    D  +  E      A 
Sbjct: 636  GPQGLQGLPGTGGPPGENGKPGEPGPKGD-AGAPGA----PGGKGDAGAPGERGPPGLAG 690

Query: 329  LSAAAASLSVAAASGGAGTGG-----GGAGGGCVAGV-----GVGA-----------GAG 367
                          GG G  G     G AG   + G+     G+G+           G G
Sbjct: 691  APGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPG 750

Query: 368  AGAGAGAKGPRSYPVIPVPSKGSFGGVLQK----FPGCGGLF--------------PHPY 409
            A    G  GPR  P  P+   G  G    K     PG  G+               P P 
Sbjct: 751  ADGVPGKDGPRG-PTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPA 809

Query: 410  TFPAAAAAFSLCHKKEDAGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFCM 469
             FP A         K + GA  E   G   G AG    +G +G   P G K     P   
Sbjct: 810  GFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSP--- 866

Query: 470  FWPPRTPG-----GLPVPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPG--GAAGS 522
               P   G     GLP P      P PP   G    + P        +   PG  G +G 
Sbjct: 867  -GGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPP---GPAGNTGAPGSPGVSGP 922

Query: 523  AEAAPPPGQPPQVVANGPGSGPPPPAGGAGSRDAL-FESPPGGSGGDCSAGSTPPADSVA 581
               A  PG+     A GP  G P P G AG   A     PPG  G   S G         
Sbjct: 923  KGDAGQPGEKGSPGAQGP-PGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESG 981

Query: 582  AAGAGAAAAGSGPAGSR-VPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLH 640
              GA   +   GP G + +P         GR    GS          GGK D     +  
Sbjct: 982  KPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGD-----RGE 1036

Query: 641  GASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPPPP 700
              S GAP +          P H       P PP P+      P     +R    P  P  
Sbjct: 1037 NGSPGAPGA----------PGH-------PGPPGPV-----GPAGKSGDRGESGPAGPAG 1074

Query: 701  PPPPPPLAQHPHHRGLLSPGGTSCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEG 760
             P P      P  +G   P G            D+ +  E     ++GH+   G     G
Sbjct: 1075 APGPAGSRGAPGPQG---PRG------------DKGETGERGAAGIKGHRGFPGNPGAPG 1119

Query: 761  RDPDDDEEEDEETEVLLGDPLVGGGRFLQG-RGPSEKGSSRDRAPAVAGAFPLGLNSSRL 819
                  ++        +G P   G R   G  GP  K  +      +    P G    R 
Sbjct: 1120 SPGPAGQQG------AIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGER- 1172

Query: 820  LQEDGKLGDPGSDLPPPPPPPLAPQKASGG 849
               +G  G PG   PP PP   AP    GG
Sbjct: 1173 -GSEGSPGHPGQPGPPGPPG--APGPCCGG 1199



 Score = 63.5 bits (153), Expect = 9e-10
 Identities = 160/634 (25%), Positives = 192/634 (30%), Gaps = 97/634 (15%)

Query: 264 VAAAAAVAGGGGLLGPHLLGAPPPPPPPPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAV 323
           V +  AV G  G  GP    A PP PP PP  +   G+P +    P +        +A  
Sbjct: 160 VKSGVAVGGLAGYPGP----AGPPGPPGPPGTSGHPGSPGS----PGYQGPPGEPGQAGP 211

Query: 324 VAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVI 383
                   A      A   G +G  G     G     G+   AG     G KG R +   
Sbjct: 212 SGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDG- 270

Query: 384 PVPSKGSFGGVLQK----FPGCGGLFPHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGA 439
               KG  G    K     PG  G  P P     A         +     AA A G  GA
Sbjct: 271 RNGEKGETGAPGLKGENGLPGENGA-PGPMGPRGAPGE----RGRPGLPGAAGARGNDGA 325

Query: 440 GGAGAAP-------------KAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQ 486
            G+   P               G  G   PAG   +   P       R   G       Q
Sbjct: 326 RGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAP-----GQRGEPGPQGHAGAQ 380

Query: 487 PPPQPPSALGCALGE---SPALLRQA--FLDLAEPGGAAGSAEAAPPPGQPPQVVANGPG 541
            PP PP   G   G+    PA +  A   +    P G AG+  A    G   +   NG  
Sbjct: 381 GPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNG-A 439

Query: 542 SGPPPPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPA 601
            G P P G  G  +A     PG  G D   GS  P +   A G   AA   G  G R PA
Sbjct: 440 KGEPGPRGERG--EAGIPGVPGAKGEDGKDGS--PGEP-GANGLPGAAGERGAPGFRGPA 494

Query: 602 PHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKLHGASAGAPHSAQTHPHHHHHPH 661
              P+ + G K   G      A  P G                  P  A   P     P 
Sbjct: 495 --GPNGIPGEKGPAG---ERGAPGPAG------------------PRGAAGEPGRDGVPG 531

Query: 662 HHHHHHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPPPPPPPPPPLAQHPHHRGLLSPGG 721
                  P  P  P      +P  PGS+     P PP P  P       P   G   P G
Sbjct: 532 GPGMRGMPGSPGGP--GSDGKPGPPGSQGESGRPGPPGPSGP----RGQPGVMGFPGPKG 585

Query: 722 TSCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPDDDEEEDEETEVLLGDPL 781
              +               +      G   P+G     G   D  +      + L G P 
Sbjct: 586 NDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPG 645

Query: 782 VGGGRFLQGRGPSEKGSSRDR-APAVAGA----------FPLGLNSSRLLQ----EDGKL 826
            GG     G+ P E G   D  AP   G            P GL  +  L+      G  
Sbjct: 646 TGGPPGENGK-PGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPE 704

Query: 827 GDPGSDLPPPPP-----PPLAPQKASGGGSSSPG 855
           G  G+  PP PP     P L       GG  SPG
Sbjct: 705 GGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPG 738



 Score = 62.4 bits (150), Expect = 2e-09
 Identities = 164/654 (25%), Positives = 201/654 (30%), Gaps = 117/654 (17%)

Query: 247 PGAHPACHPLSSVKAAAVAAAAAVAGGGGLLGPHLLGAP----PPPPPPPPPLAELAGAP 302
           PG + A  P+    A        + G  G  G    GA      P PP PP  A   G+P
Sbjct: 290 PGENGAPGPMGPRGAPGERGRPGLPGAAGARGND--GARGSDGQPGPPGPPGTAGFPGSP 347

Query: 303 HAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGGGAGGGCVAGVGV 362
            A  +         +        A            A A G  G  G     G    +G 
Sbjct: 348 GAKGEVGPAGSPGSN-------GAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGP 400

Query: 363 GAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLFPHPYTFPAAAAAFSLCH 422
               GA    GA+GP   P     + G  GG  +  PG  G    P              
Sbjct: 401 AGIPGAPGLMGARGPPG-PAGANGAPGLRGGAGE--PGKNGAKGEPGP------------ 445

Query: 423 KKEDAGAAAEALGGA-GAGGAGAAP-KAGLSGLFWPAGRKDAFYPPFCMFWPPRTPGGLP 480
           + E   A    + GA G  G   +P + G +GL   AG + A       F  P  P G+P
Sbjct: 446 RGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGA-----PGFRGPAGPNGIP 500

Query: 481 ---VPTYLQPPPQPPSALGCALGESPALLRQAFLDLAEPG--GAAGSAEAAPPPGQPPQV 535
               P   +  P P    G A                EPG  G  G       PG P   
Sbjct: 501 GEKGPAGERGAPGPAGPRGAA---------------GEPGRDGVPGGPGMRGMPGSPGGP 545

Query: 536 VANG----PGS-------GPPPPAGGAGSRDAL-FESPPGGS---------GGDCSAGST 574
            ++G    PGS       GPP P+G  G    + F  P G           GG    G  
Sbjct: 546 GSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQ 605

Query: 575 PPADSVAAAGAGAAAAGSGPAGSR-VPAPHHPHLLEGRKAGGGSYHHSSAFRPVGGKDDA 633
            P       G       +GP G +    P  P  L+G    GG    +      G K DA
Sbjct: 606 GPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDA 665

Query: 634 ESLAKLHG-ASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPGSERHH 692
            +     G   AGAP   +  P              P    +P L     P  P   +  
Sbjct: 666 GAPGAPGGKGDAGAP--GERGP--------------PGLAGAPGLRGGAGPPGPEGGKGA 709

Query: 693 PAPPPPPPPPPPPPLAQHPHHR-GLLSPGGTSCSYPSEDSSEDEDDEEEEQEVDVEGHKP 751
             PP PP     P L   P  R GL SPG      P  D  E      +     V G   
Sbjct: 710 AGPPGPPGAAGTPGLQGMPGERGGLGSPG------PKGDKGEPGGPGAD----GVPGKDG 759

Query: 752 PEGEEEEEGRDPDDDEEEDEETEVLLGDPLVGGGRFLQGRGPSEKGSSRDRAPA-VAGA- 809
           P G     G      +  D+      G P + G R      P E+G +    PA   GA 
Sbjct: 760 PRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPR----GSPGERGETGPPGPAGFPGAP 815

Query: 810 ----FPLGLNSSRLLQEDGKLGDPGSDLPPPPPPPLAPQKASG--GGSSSPGSP 857
                P G        E G+ G PG   PP    P  P    G  G   SPG P
Sbjct: 816 GQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGP 869



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 167/705 (23%), Positives = 207/705 (29%), Gaps = 140/705 (19%)

Query: 236  NGGSRKRALPQPGAHPACH-PLSSVKAAAVAAAAAVAGGGGLLG-PHLLGAPPPPPPP-- 291
            NG   +R  P P  H     P                G  G+ G P L+GA  PP P   
Sbjct: 362  NGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGA 421

Query: 292  --PPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGG 349
               P L   AG P  +  +     +     E        +  A        + G  G  G
Sbjct: 422  NGAPGLRGGAGEPGKNGAK----GEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANG 477

Query: 350  GGAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPS--KGSFGGVLQKFPGCGGL--F 405
                 G     G    AG     G KGP      P P+  +G+ G      PG  G+   
Sbjct: 478  LPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGE-----PGRDGVPGG 532

Query: 406  PHPYTFPAAAAAFSLCHKKEDAGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYP 465
            P     P +        K    G+  E+      G +G   + G+ G   P G   A   
Sbjct: 533  PGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGA--- 589

Query: 466  PFCMFWPPRT-----PGGLPVPTYLQPPPQ-PPSALGCALGESPALLRQAFLDLAEPGGA 519
                  P +      PGG        P PQ PP   G    + P            P G 
Sbjct: 590  ------PGKNGERGGPGG--------PGPQGPPGKNGETGPQGPP----------GPTGP 625

Query: 520  AGSAEAAPPPGQPPQVVANGPGSGPPPPAGGAGSR-----DALFESPPGGSGGDCSAGST 574
             G      PPG  PQ +   PG+G PP   G         DA     PGG G   + G  
Sbjct: 626  GGDKGDTGPPG--PQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGER 683

Query: 575  PPADSVAAAGAGAAAAGSGPAGSRVPA--PHHPHL--------LEGRKAGGGS------- 617
             P     A G    A   GP G +  A  P  P          + G + G GS       
Sbjct: 684  GPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDK 743

Query: 618  -YHHSSAFRPVGGKDDAESLA--------------KLHGASAGAPHSAQTHPHHHHHPHH 662
                      V GKD                    K  G + G P  A         P  
Sbjct: 744  GEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIA--------GPRG 795

Query: 663  HHHHHHPPQPPSPLLL--LPPQPDEPGSERHHPAP-------PPPPPPPP-------PPP 706
                     PP P      P Q  EPG +    AP       PP    PP       PP 
Sbjct: 796  SPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPG 855

Query: 707  LAQHPHHRGLLSPGGT-SCSYPSEDSSEDEDDEEEEQEVDVEGHKPPEGEEEEEGRDPDD 765
                   RG  SPGG  +  +P                    G+  P G     G+D   
Sbjct: 856  PQGVKGERG--SPGGPGAAGFPGARGLPGPPGS--------NGNPGPPGPSGSPGKDGPP 905

Query: 766  DEEEDEETEVLLGDPLVGGGRFLQGRGPSEKGSSRDRAPAVAGAFPLGLNSSRLLQEDGK 825
                +       G P V G +   G+ P EKGS   + P  A   PLG+  + +    G 
Sbjct: 906  GPAGNTGAP---GSPGVSGPKGDAGQ-PGEKGSPGAQGPPGAPG-PLGI--AGITGARGL 958

Query: 826  LGDPGSDLPPPPPPPLAPQKASG-------GGSSSPGSPVHHPSL 863
             G PG   P   P P   +  SG        G   P  P   P L
Sbjct: 959  AGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGL 1003



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 105/413 (25%), Positives = 122/413 (29%), Gaps = 73/413 (17%)

Query: 237  GGSRKRALPQPGAHPACHPLSSVKAAAVAAAAAVAGGGGLLG-PHLLGAPPPP-----PP 290
            GG    A P  G+ PA  P        V       GG G  G P   G P PP     P 
Sbjct: 836  GGPPGVAGPPGGSGPAGPP----GPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPG 891

Query: 291  PPPPLAELAGAPHAHHKRPRFDDDDDSLQEAAVVAAASLSAAAASLSVAAASGGAGTGGG 350
            PP P    +G+P         D             +  +S            G  G  G 
Sbjct: 892  PPGP----SGSPGK-------DGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGP 940

Query: 351  GAGGGCVAGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGGVLQKFPGCGGLF----- 405
                G +   G+    G     G  GPR  P  P   KG  G      PG  GL      
Sbjct: 941  PGAPGPLGIAGITGARGLAGPPGMPGPRGSPG-PQGVKGESGK-----PGANGLSGERGP 994

Query: 406  PHPYTFPAAAAAFSLCHKKEDAGAAAEAL-------GGAGAGGAGAAPKA-------GLS 451
            P P   P  A          D    ++ L       GG G  G   +P A       G  
Sbjct: 995  PGPQGLPGLAGTAG--EPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPP 1052

Query: 452  GLFWPAGRKDAFYPPFCMFWPPRTPGGLPVPTYLQ--PPPQPPSALGCALGESPALLRQA 509
            G   PAG+             P  P G P P   +  P PQ P       GE  A   + 
Sbjct: 1053 GPVGPAGKSGDRGES-----GPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKG 1107

Query: 510  FLDL-------AEPG-----GAAGSAEAAPP-----PGQPPQVVANGPGSGPPPPAGGAG 552
                         PG     GA GS   A P     P  PP         GP  P G  G
Sbjct: 1108 HRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRG 1167

Query: 553  SRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAA-AGSGPAGSRVPAPHH 604
            +R         G  G       P A      G GAAA AG G   +   AP++
Sbjct: 1168 NRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGVGAAAIAGIGGEKAGGFAPYY 1220



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 114/471 (24%), Positives = 141/471 (29%), Gaps = 102/471 (21%)

Query: 472 PPRTPG-----GLPVPTYLQPPPQPPSAL-GCALGE---SPALLRQAFLDLAEPGGAAGS 522
           PP  PG     G+P        P PP     C  G    SP             GG AG 
Sbjct: 113 PPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGY 172

Query: 523 AEAAPPPGQP-PQVVANGPGS-------GPPPPAGGAGSRDALFESPPGGSGGDCSAGST 574
              A PPG P P   +  PGS       GPP   G AG        PPG  G    +G  
Sbjct: 173 PGPAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGP-----SGPPGPPGAIGPSGPA 227

Query: 575 PPADSVAAAGAGAAAAGSGPAGSRVPA--PHHPHLLEGRKAGGGSYHHSSAFRP------ 626
                    G        GP G + PA  P  P +   R   G +        P      
Sbjct: 228 GKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGEN 287

Query: 627 -VGGKDDAESLAKLHGASA-----GAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLL-- 678
            + G++ A       GA       G P +A      +           PP PP       
Sbjct: 288 GLPGENGAPGPMGPRGAPGERGRPGLPGAAGA--RGNDGARGSDGQPGPPGPPGTAGFPG 345

Query: 679 ------------------LPPQPDEPGSERHHPAPPPPPPP-----------PPPPPLAQ 709
                              P Q  EPG + H  A  PP PP             P  +  
Sbjct: 346 SPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPG 405

Query: 710 HPHHRGLLSPGGTS-----------CSYPSEDSSEDEDDEEEEQ-EVDVEGHKPPEGEEE 757
            P   G   P G +              P ++ ++ E     E+ E  + G     G + 
Sbjct: 406 APGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPG---VPGAKG 462

Query: 758 EEGRDPDDDEEEDEETEVLLGDPLVGGGRFLQGRG--PSEKGSSRDR-APAVAGAFPLGL 814
           E+G+D    E          G+    G R   G    P EKG + +R AP  AG      
Sbjct: 463 EDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAG 522

Query: 815 NSSR--------LLQEDGKLGDPGSDLPPPPPPPLAPQKASGGGSSSPGSP 857
              R        +    G  G PGSD  P PP        S G S  PG P
Sbjct: 523 EPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPP-------GSQGESGRPGPP 566



 Score = 37.4 bits (85), Expect = 0.071
 Identities = 92/364 (25%), Positives = 103/364 (28%), Gaps = 66/364 (18%)

Query: 511 LDLAEPGGAAGSAEAAPPPGQPPQVVANGP-GSGPPPPAGGAGSRDALFESPPG--GSGG 567
           LD   P    G   A  P  QPP      P G GP  P G  G        PPG  G  G
Sbjct: 72  LDCPNPEIPFGECCAVCP--QPPTAPTRPPNGQGPQGPKGDPG--------PPGIPGRNG 121

Query: 568 DCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLLEGRKAGGGSYHHSSAFRPV 627
           D      P                 G  GS    P  P + E    G  +Y       P 
Sbjct: 122 DPGIPGQP-----------------GSPGS----PGPPGICESCPTGPQNYS------PQ 154

Query: 628 GGKDDAESLAKLHGASAGAPHSAQTHPHHHHHPHHHHHHHHPPQPPSPLLLLPPQPDEPG 687
               D +S   + G +     +    P     P       HP  P SP    P  P EPG
Sbjct: 155 YDSYDVKSGVAVGGLAGYPGPAGPPGP-----PGPPGTSGHPGSPGSPGYQGP--PGEPG 207

Query: 688 SERHHPAPPPPPPPPPPPPLAQ--------HPHHRGLLSPGGTS-----CSYPSEDSSED 734
                  P PP    P  P  +         P  RGL  P G         +P       
Sbjct: 208 QAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRG 267

Query: 735 EDDEE-EEQEVDVEGHKPPEGEEEEEGRDPDDDEEEDEETEVLLGDPLVGGGRFLQGRGP 793
            D    E+ E    G K   G   E G                 G P   G R   G   
Sbjct: 268 FDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARG 327

Query: 794 SEKGSSRDRAPAVAGAFPLGLNSSRLLQEDGKLGDPGSDLPPPPPPPLAPQKASGGGSSS 853
           S+        P  AG FP    S     E G  G PGS+  P       PQ    G    
Sbjct: 328 SDGQPGPPGPPGTAG-FP---GSPGAKGEVGPAGSPGSNGAPGQRGEPGPQ-GHAGAQGP 382

Query: 854 PGSP 857
           PG P
Sbjct: 383 PGPP 386


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.135    0.422 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,662,789
Number of Sequences: 37866
Number of extensions: 4635900
Number of successful extensions: 130569
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1524
Number of HSP's successfully gapped in prelim test: 1938
Number of HSP's that attempted gapping in prelim test: 37206
Number of HSP's gapped (non-prelim): 51140
length of query: 996
length of database: 18,247,518
effective HSP length: 112
effective length of query: 884
effective length of database: 14,006,526
effective search space: 12381768984
effective search space used: 12381768984
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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