BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239747320 PREDICTED: forkhead box protein O6 [Homo sapiens] (589 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239747320 PREDICTED: forkhead box protein O6 [Homo sapiens] 1233 0.0 gi|239741142 PREDICTED: forkhead box protein O6 [Homo sapiens] 337 1e-92 gi|239752748 PREDICTED: similar to forkhead box O6 [Homo sapiens] 279 4e-75 gi|103472003 forkhead box O4 [Homo sapiens] 190 4e-48 gi|42519916 forkhead box O3A [Homo sapiens] 145 1e-34 gi|4503739 forkhead box O3A [Homo sapiens] 145 1e-34 gi|9257222 forkhead box O1 [Homo sapiens] 141 2e-33 gi|24497501 forkhead box A1 [Homo sapiens] 57 6e-08 gi|195947376 forkhead box I2 [Homo sapiens] 54 5e-07 gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 51 3e-06 gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 51 3e-06 gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 51 3e-06 gi|22779860 forkhead box L1 [Homo sapiens] 51 3e-06 gi|110832843 TBP-associated factor 4 [Homo sapiens] 50 4e-06 gi|50345831 forkhead box J3 [Homo sapiens] 50 6e-06 gi|119508426 alpha 3 type IX collagen [Homo sapiens] 49 1e-05 gi|8923842 forkhead box J2 [Homo sapiens] 49 1e-05 gi|39812378 RAN binding protein 9 [Homo sapiens] 48 2e-05 gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 48 2e-05 gi|134142824 forkhead box D2 [Homo sapiens] 48 2e-05 gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens] 47 4e-05 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 47 6e-05 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 47 6e-05 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 47 6e-05 gi|160707881 formin 2 [Homo sapiens] 47 6e-05 gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 47 6e-05 gi|24497506 forkhead box A3 [Homo sapiens] 47 6e-05 gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 46 8e-05 gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 46 8e-05 gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 46 8e-05 >gi|239747320 PREDICTED: forkhead box protein O6 [Homo sapiens] Length = 589 Score = 1233 bits (3189), Expect = 0.0 Identities = 589/589 (100%), Positives = 589/589 (100%) Query: 1 MAAKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRAT 60 MAAKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRAT Sbjct: 1 MAAKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRAT 60 Query: 61 APAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVR 120 APAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVR Sbjct: 61 APAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVR 120 Query: 121 YVPYFKDKGDSNSSAGWKVGASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTE 180 YVPYFKDKGDSNSSAGWKVGASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTE Sbjct: 121 YVPYFKDKGDSNSSAGWKVGASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTE 180 Query: 181 SCSSRAPSSSFVLRGSPAPRADGGGEVTFPEVATCEVVDLGIGPQARAFSVPLGASLQGW 240 SCSSRAPSSSFVLRGSPAPRADGGGEVTFPEVATCEVVDLGIGPQARAFSVPLGASLQGW Sbjct: 181 SCSSRAPSSSFVLRGSPAPRADGGGEVTFPEVATCEVVDLGIGPQARAFSVPLGASLQGW 240 Query: 241 GTAAGPSPELGSGQGWLPFYPFSTADPSAEDLHMASGPWHHPGHIFCQEEAWTENLNFTP 300 GTAAGPSPELGSGQGWLPFYPFSTADPSAEDLHMASGPWHHPGHIFCQEEAWTENLNFTP Sbjct: 241 GTAAGPSPELGSGQGWLPFYPFSTADPSAEDLHMASGPWHHPGHIFCQEEAWTENLNFTP 300 Query: 301 DGRANGLPRALNQGLQRTRQGKAGKSQLLPSKARKCQRQGAWGPEESDQCLELGQYLDQE 360 DGRANGLPRALNQGLQRTRQGKAGKSQLLPSKARKCQRQGAWGPEESDQCLELGQYLDQE Sbjct: 301 DGRANGLPRALNQGLQRTRQGKAGKSQLLPSKARKCQRQGAWGPEESDQCLELGQYLDQE 360 Query: 361 VEATRTGLAKAGSDMGSTGDWHSRIKKRMYGEMAEVFWRVNGDFATHCGDFEKAPTARGL 420 VEATRTGLAKAGSDMGSTGDWHSRIKKRMYGEMAEVFWRVNGDFATHCGDFEKAPTARGL Sbjct: 361 VEATRTGLAKAGSDMGSTGDWHSRIKKRMYGEMAEVFWRVNGDFATHCGDFEKAPTARGL 420 Query: 421 EGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMT 480 EGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMT Sbjct: 421 EGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMT 480 Query: 481 LPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRFPADLDLDMFS 540 LPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRFPADLDLDMFS Sbjct: 481 LPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRFPADLDLDMFS 540 Query: 541 GSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPPNQSWVPG 589 GSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPPNQSWVPG Sbjct: 541 GSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPPNQSWVPG 589 >gi|239741142 PREDICTED: forkhead box protein O6 [Homo sapiens] Length = 492 Score = 337 bits (865), Expect = 1e-92 Identities = 163/170 (95%), Positives = 164/170 (96%) Query: 420 LEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLM 479 L+G Q P PAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLM Sbjct: 323 LDGAQDAYGPRPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLM 382 Query: 480 TLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRFPADLDLDMF 539 TLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRFPADLDLDMF Sbjct: 383 TLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRFPADLDLDMF 442 Query: 540 SGSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPPNQSWVPG 589 SGSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPPNQSWVPG Sbjct: 443 SGSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPPNQSWVPG 492 Score = 289 bits (739), Expect = 6e-78 Identities = 138/138 (100%), Positives = 138/138 (100%) Query: 1 MAAKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRAT 60 MAAKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRAT Sbjct: 1 MAAKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRAT 60 Query: 61 APAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVR 120 APAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVR Sbjct: 61 APAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVR 120 Query: 121 YVPYFKDKGDSNSSAGWK 138 YVPYFKDKGDSNSSAGWK Sbjct: 121 YVPYFKDKGDSNSSAGWK 138 >gi|239752748 PREDICTED: similar to forkhead box O6 [Homo sapiens] Length = 562 Score = 279 bits (714), Expect = 4e-75 Identities = 134/137 (97%), Positives = 134/137 (97%) Query: 2 AAKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRATA 61 AAKLRAH VDVDPDFAPQSRP S TWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRATA Sbjct: 179 AAKLRAHHVDVDPDFAPQSRPHSSTWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRATA 238 Query: 62 PAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVRY 121 PAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVRY Sbjct: 239 PAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVRY 298 Query: 122 VPYFKDKGDSNSSAGWK 138 VPYFKDKGDSNSSAGWK Sbjct: 299 VPYFKDKGDSNSSAGWK 315 Score = 114 bits (285), Expect = 3e-25 Identities = 83/180 (46%), Positives = 90/180 (50%), Gaps = 30/180 (16%) Query: 430 PPAPRPGPVLGAPGELALAGAAAA-------------YPGKGAAPYAPPAPSRSALAHPI 476 P AP PGPV A A + A+ P G A + ALA P Sbjct: 393 PSAPAPGPVPAAAKWAASPASHASDDYEAWADFRGGGRPLLGEAAELEDDEALEALA-PS 451 Query: 477 SLMTLPGEAGAA----GLAPPGHA---AAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDR 529 S + P A A G PG A GGP G G A G L A D Sbjct: 452 SPLMYPSPASALSPALGSRCPGELPRLAELGGPLG-----LHGGGGAGLPEGLLDGAQDA 506 Query: 530 FPADLDLDMFSGSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPPNQSWVPG 589 + +G+LECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPPNQSWVPG Sbjct: 507 YGPRAR----AGTLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPPNQSWVPG 562 >gi|103472003 forkhead box O4 [Homo sapiens] Length = 505 Score = 190 bits (482), Expect = 4e-48 Identities = 185/588 (31%), Positives = 253/588 (43%), Gaps = 132/588 (22%) Query: 10 VDVDPDFAPQSRPRSCTWPLPQPDLAGD--EDGALGAGVAEGAEDCGPERRATAPAMAPA 67 +D+DPDF PQSRPRSCTWPLP+P++A E + + E G P+ P Sbjct: 16 IDLDPDFEPQSRPRSCTWPLPRPEIANQPSEPPEVEPDLGEKVHTEGRSEPILLPSRLPE 75 Query: 68 PP-------LGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVR 120 P LGA GP + SRRNAWGN SYA+LI++AIESAP+KRLTL+QIY+WMVR Sbjct: 76 PAGGPQPGILGAVTGP--RKGGSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVR 133 Query: 121 YVPYFKDKGDSNSSAGWKVGASGWGGGWGRRLGLPGAARCVGLQE---GRQKEGFLAPPG 177 VPYFKDKGDSNSSAGWK R L ++ + + G+ L P G Sbjct: 134 TVPYFKDKGDSNSSAGWKNSI---------RHNLSLHSKFIKVHNEATGKSSWWMLNPEG 184 Query: 178 VTESCSSRAP--------SSSFVLRG-SPAPRADGGGEVTFPEVATCEVVDLGIGPQARA 228 S +AP SSS +LRG S AP+ P V L P+ Sbjct: 185 ---GKSGKAPRRRAASMDSSSKLLRGRSKAPKKK-------PSV-------LPAPPEGAT 227 Query: 229 FSVPLGASLQGWGTAAGPSPELGSGQGWLPFYPFSTADPSAEDLHMASGPWHHPGHIFCQ 288 + P+G + G+ + E W F P S+++ S+ ++ + + Sbjct: 228 PTSPVGHFAKWSGSPCSRNRE--EADMWTTFRPRSSSNASSVSTRLSP--------LRPE 277 Query: 289 EEAWTENLNFTPDGRANGLPRALNQGLQRTRQGKAGKSQLLPSKARKCQRQGAWGPEESD 348 E E + + A G+P LN+GL+ S L S Sbjct: 278 SEVLAEEIPASVSSYAGGVPPTLNEGLELLDGLNLTSSHSLLS----------------- 320 Query: 349 QCLELGQYLDQEVEATRTGLAKAG-SDMGSTGDWHSRIKKRMYGEMAEVFWRVNGDFATH 407 R+GL+ G TG H+ + +F G + Sbjct: 321 ----------------RSGLSGFSLQHPGVTGPLHT--------YSSSLFSPAEGPLSAG 356 Query: 408 CGDFEKAPTARGLEGRQVVPPPPPA----PRPGPVLG-APGELALAG---AAAAYPGKGA 459 G F + L PPPPA + P+L AP L L G ++ G G Sbjct: 357 EGCFSSSQALEALLTSDT--PPPPADVLMTQVDPILSQAPTLLLLGGLPSSSKLATGVGL 414 Query: 460 APYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAA 519 P AP S+L +S++ P +A + P L L P A Sbjct: 415 CPKPLEAPGPSSLVPTLSMIAPPPVMASAPI------------PKALGTPVLTPPTEA-- 460 Query: 520 AGPLGAAPDRFPADLDLDMFSGSLECDVESIILNDFMDSDE-MDFNFD 566 A+ DR P DLDLDM+ +LECD+++II +D MD E +DFNF+ Sbjct: 461 -----ASQDRMPQDLDLDMYMENLECDMDNII-SDLMDEGEGLDFNFE 502 >gi|42519916 forkhead box O3A [Homo sapiens] Length = 673 Score = 145 bits (365), Expect = 1e-34 Identities = 91/199 (45%), Positives = 106/199 (53%), Gaps = 63/199 (31%) Query: 3 AKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAG-----------------------DED 39 A L +V++DP+F PQSRPRSCTWPL +P+L DED Sbjct: 9 APLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEEEDDEDDED 68 Query: 40 G--------ALGAG------------------VAEGAEDCGPERRATAPAMA-------- 65 G A+G G +A G +D G A ++ Sbjct: 69 GGGRAGSAMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLSGGTQALLQ 128 Query: 66 -----PAPPLGAEVGPLRKAK-SSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMV 119 P P GA G + K SSRRNAWGNLSYADLIT+AIES+PDKRLTLSQIY+WMV Sbjct: 129 PQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMV 188 Query: 120 RYVPYFKDKGDSNSSAGWK 138 R VPYFKDKGDSNSSAGWK Sbjct: 189 RCVPYFKDKGDSNSSAGWK 207 Score = 72.0 bits (175), Expect = 1e-12 Identities = 43/92 (46%), Positives = 58/92 (63%), Gaps = 10/92 (10%) Query: 507 LLDALPGP--YAAAAAGPLGAAPDRFPADLDLDMFSGSLECDVESIILNDFMDSDEMDFN 564 L D+L G Y+ +A P+ ++FP+DLDLDMF+GSLECD+ESII ++ MD+D +DFN Sbjct: 583 LSDSLSGSSLYSTSANLPV-MGHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFN 641 Query: 565 FDSALPPP------PPGLAGA-PPPNQSWVPG 589 FDS + GA +QSWVPG Sbjct: 642 FDSLISTQNVVGLNVGNFTGAKQASSQSWVPG 673 >gi|4503739 forkhead box O3A [Homo sapiens] Length = 673 Score = 145 bits (365), Expect = 1e-34 Identities = 91/199 (45%), Positives = 106/199 (53%), Gaps = 63/199 (31%) Query: 3 AKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAG-----------------------DED 39 A L +V++DP+F PQSRPRSCTWPL +P+L DED Sbjct: 9 APLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEEEDDEDDED 68 Query: 40 G--------ALGAG------------------VAEGAEDCGPERRATAPAMA-------- 65 G A+G G +A G +D G A ++ Sbjct: 69 GGGRAGSAMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLSGGTQALLQ 128 Query: 66 -----PAPPLGAEVGPLRKAK-SSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMV 119 P P GA G + K SSRRNAWGNLSYADLIT+AIES+PDKRLTLSQIY+WMV Sbjct: 129 PQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMV 188 Query: 120 RYVPYFKDKGDSNSSAGWK 138 R VPYFKDKGDSNSSAGWK Sbjct: 189 RCVPYFKDKGDSNSSAGWK 207 Score = 72.0 bits (175), Expect = 1e-12 Identities = 43/92 (46%), Positives = 58/92 (63%), Gaps = 10/92 (10%) Query: 507 LLDALPGP--YAAAAAGPLGAAPDRFPADLDLDMFSGSLECDVESIILNDFMDSDEMDFN 564 L D+L G Y+ +A P+ ++FP+DLDLDMF+GSLECD+ESII ++ MD+D +DFN Sbjct: 583 LSDSLSGSSLYSTSANLPV-MGHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFN 641 Query: 565 FDSALPPP------PPGLAGA-PPPNQSWVPG 589 FDS + GA +QSWVPG Sbjct: 642 FDSLISTQNVVGLNVGNFTGAKQASSQSWVPG 673 >gi|9257222 forkhead box O1 [Homo sapiens] Length = 655 Score = 141 bits (355), Expect = 2e-33 Identities = 88/203 (43%), Positives = 100/203 (49%), Gaps = 74/203 (36%) Query: 10 VDVDPDFAPQSRPRSCTWPLPQPDL----------------AGDEDGALGAGVAEGA--- 50 V++DPDF P RPRSCTWPLP+P+ A + D A G A A Sbjct: 8 VEIDPDFEPLPRPRSCTWPLPRPEFSQSNSATSSPAPSGSAAANPDAAAGLPSASAAAVS 67 Query: 51 -------------ED------------------------CGPERRATAPAMAPAPPLGAE 73 ED CG + A + PAPP Sbjct: 68 ADFMSNLSLLEESEDFPQAPGSVAAAVAAAAAAAATGGLCGDFQGPEAGCLHPAPPQPPP 127 Query: 74 VGPL------------------RKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIY 115 GPL RK+ SSRRNAWGNLSYADLITKAIES+ +KRLTLSQIY Sbjct: 128 PGPLSQHPPVPPAAAGPLAGQPRKSSSSRRNAWGNLSYADLITKAIESSAEKRLTLSQIY 187 Query: 116 DWMVRYVPYFKDKGDSNSSAGWK 138 +WMV+ VPYFKDKGDSNSSAGWK Sbjct: 188 EWMVKSVPYFKDKGDSNSSAGWK 210 Score = 54.7 bits (130), Expect = 2e-07 Identities = 25/43 (58%), Positives = 32/43 (74%), Gaps = 1/43 (2%) Query: 528 DRFPADLDLDMFSGSLECDVESIILNDFMDSDEMDFNFDSALP 570 ++ P+DLD MF L+CD+ESII ND MD D +DFNFD+ LP Sbjct: 596 EKLPSDLD-GMFIERLDCDMESIIRNDLMDGDTLDFNFDNVLP 637 Score = 33.1 bits (74), Expect = 0.73 Identities = 43/143 (30%), Positives = 48/143 (33%), Gaps = 31/143 (21%) Query: 410 DFEKAPTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAA-PYAPPAPS 468 DFE P R P P P A A +G+AAA P A P A A Sbjct: 13 DFEPLPRPRSCTW------PLPRPEFSQSNSATSSPAPSGSAAANPDAAAGLPSASAAAV 66 Query: 469 RSALAHPISLMT-------LPGE------AGAAGLAPPGHAAAFGGPPGGLLLDALP--- 512 + +SL+ PG A AA A G F GP G L A P Sbjct: 67 SADFMSNLSLLEESEDFPQAPGSVAAAVAAAAAAAATGGLCGDFQGPEAGCLHPAPPQPP 126 Query: 513 --------GPYAAAAAGPLGAAP 527 P AAAGPL P Sbjct: 127 PPGPLSQHPPVPPAAAGPLAGQP 149 >gi|24497501 forkhead box A1 [Homo sapiens] Length = 472 Score = 56.6 bits (135), Expect = 6e-08 Identities = 35/95 (36%), Positives = 46/95 (48%), Gaps = 8/95 (8%) Query: 40 GALGAGVAEGAEDCGPERRATAPAMAPAPPLGAEVGPLRKA--------KSSRRNAWGNL 91 GA+GA A GP A P M+P + +G R K S +A Sbjct: 114 GAMGAQQAASMNGLGPYAAAMNPCMSPMAYAPSNLGRSRAGGGGDAKTFKRSYPHAKPPY 173 Query: 92 SYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFK 126 SY LIT AI+ AP K LTLS+IY W++ PY++ Sbjct: 174 SYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYR 208 >gi|195947376 forkhead box I2 [Homo sapiens] Length = 318 Score = 53.5 bits (127), Expect = 5e-07 Identities = 49/150 (32%), Positives = 68/150 (45%), Gaps = 31/150 (20%) Query: 11 DVDPDFAPQSRPRSCTWPLPQPDLAGDEDGALGAG--VAEGAEDCGPERRATAPAMAP-- 66 D+ P AP + ++ P P + GA+G G + A P+ A+ P AP Sbjct: 7 DLGPSSAPPGQAQATAHP---PGYEPGDLGAVGGGPLLWVNAPALSPKSYASGPGPAPPY 63 Query: 67 -APPLGAEVGPLRKAKSSRRNA---WGNLS--------------YADLITKAIESAPDKR 108 AP GA GPL A A W +LS Y+ LI AI+SAP ++ Sbjct: 64 AAPSYGAP-GPLLGAPGGLAGADLAWLSLSGQQELLRLVRPPYSYSALIAMAIQSAPLRK 122 Query: 109 LTLSQIYDWMVRYVPYFKDKGDSNSSAGWK 138 LTLSQIY ++ P++K S AGW+ Sbjct: 123 LTLSQIYQYVAGNFPFYK-----RSKAGWQ 147 >gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo sapiens] Length = 1650 Score = 50.8 bits (120), Expect = 3e-06 Identities = 43/118 (36%), Positives = 49/118 (41%), Gaps = 25/118 (21%) Query: 415 PTARGLEGRQVVPPPPPAP---RPGPVLGAPGELALAGAAAAYPGKG-AAPYAPPAPSRS 470 P G EG + P PP AP P + G PGE L G A KG P PP P+ S Sbjct: 871 PGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGS 930 Query: 471 ALAHPISLMTLPGEAGAAG----LAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLG 524 PGE GAAG + PPG GPPG +PG GP+G Sbjct: 931 -----------PGERGAAGSGGPIGPPGRPGP-QGPPGAAGEKGVPG-----EKGPIG 971 Score = 45.8 bits (107), Expect = 1e-04 Identities = 42/127 (33%), Positives = 50/127 (39%), Gaps = 24/127 (18%) Query: 415 PTAR-GLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALA 473 PT R G++G +P P P G GE+ G KG + PP P Sbjct: 972 PTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGE--HGPPGPPG---- 1025 Query: 474 HPISLMTLPGEAGAAG----LAPPGHAAA--------FGGPPGGLLLDALPGPYA----A 517 PI + PG AGA G P GH A F GPPG + L LPGP Sbjct: 1026 -PIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGET 1084 Query: 518 AAAGPLG 524 GP+G Sbjct: 1085 GDVGPMG 1091 Score = 40.0 bits (92), Expect = 0.006 Identities = 38/94 (40%), Positives = 41/94 (43%), Gaps = 12/94 (12%) Query: 435 PGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEAGAAGLA-PP 493 PGP G PGE L G A KG P P AP + P L PGE G G A P Sbjct: 859 PGPP-GPPGEQGLPGTAGKEGTKGD-PGPPGAPGKDG---PAGLRGFPGERGLPGTAGGP 913 Query: 494 GHAAAFG--GPPGGLLLDALPGPY-AAAAAGPLG 524 G G GPPG PG AA + GP+G Sbjct: 914 GLKGNEGPSGPPGPA---GSPGERGAAGSGGPIG 944 Score = 39.3 bits (90), Expect = 0.010 Identities = 46/143 (32%), Positives = 55/143 (38%), Gaps = 43/143 (30%) Query: 415 PTARGLEGRQ-VVPPPPPAPRPGP--VLGAPGELALAGAAAAYPGKGA-APYAPP----- 465 P A G G+ V P PA +PGP + G PG + G A G P PP Sbjct: 1255 PGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGL 1314 Query: 466 ---APSRSALAHP--ISLMTLPGEAGAAG----------------LAPPGHAAAF--GGP 502 A ++ HP I L+ PGE G G + PG + GGP Sbjct: 1315 RGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGP 1374 Query: 503 PGGLLLDALPGPYAAAAAGPLGA 525 PG LPGP AGP GA Sbjct: 1375 PG------LPGP-----AGPKGA 1386 Score = 38.9 bits (89), Expect = 0.013 Identities = 39/118 (33%), Positives = 45/118 (38%), Gaps = 14/118 (11%) Query: 417 ARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAA------YPGKGAA--PYAPPAPS 468 A+G G P P +P P G PG L G A + GKGA P A AP Sbjct: 1203 AKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPG 1262 Query: 469 RSALAHPISLMTLPGEAGAAGL----APPGHAAAFG--GPPGGLLLDALPGPYAAAAA 520 ++ P PG G GL G A G GPPG + LPG A A Sbjct: 1263 KTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGA 1320 Score = 34.7 bits (78), Expect = 0.25 Identities = 35/112 (31%), Positives = 41/112 (36%), Gaps = 20/112 (17%) Query: 415 PTARGLEGRQVVPPPPPAPRP-GPV-----LGAPGELALAGAAAAYPGKGA-------AP 461 P +G +G + PP P P GPV GA GE G + KG P Sbjct: 1006 PGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGP 1065 Query: 462 YAP------PAPS-RSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGL 506 P P PS + M PG G G A P A GPPGG+ Sbjct: 1066 PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGV 1117 Score = 32.3 bits (72), Expect = 1.3 Identities = 27/85 (31%), Positives = 30/85 (35%), Gaps = 6/85 (7%) Query: 440 GAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAF 499 G PGE G A P P I LPGE+G GL P Sbjct: 479 GLPGEKGHRGDTGAQ----GLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGI 534 Query: 500 GGPPGGLLLDALPGPYAAAAAGPLG 524 GPPG +D GP + GP G Sbjct: 535 PGPPGVRGMDGPQGP--KGSLGPQG 557 Score = 32.0 bits (71), Expect = 1.6 Identities = 35/105 (33%), Positives = 37/105 (35%), Gaps = 23/105 (21%) Query: 430 PPAP-----RPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGE 484 PP P RPGP LG PG L G + P P P L PG+ Sbjct: 402 PPGPMGYTGRPGP-LGQPGSPGLKGESG-----DLGPQGPRGPQ--------GLTGPPGK 447 Query: 485 AGAAGLAPPGHAAAFGGPP---GGLLLDALPG-PYAAAAAGPLGA 525 AG G A A G P G D LPG P G GA Sbjct: 448 AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGA 492 Score = 31.2 bits (69), Expect = 2.8 Identities = 35/137 (25%), Positives = 46/137 (33%), Gaps = 22/137 (16%) Query: 420 LEGRQVVPPPPPAPRPGPVLGAPGELALAGAAA-----AYPGKGAAPYA--PPAPSRSAL 472 LE +V PP P ++G PG G PG+ P + P P ++L Sbjct: 305 LEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSL 364 Query: 473 AHPISLMTLPGEAGAAGLAPPGHA--------AAFGGPPGGLLLDALPGPYA-------A 517 P + G+ G A A A GPPG + PGP Sbjct: 365 MLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLK 424 Query: 518 AAAGPLGAAPDRFPADL 534 +G LG R P L Sbjct: 425 GESGDLGPQGPRGPQGL 441 Score = 31.2 bits (69), Expect = 2.8 Identities = 41/129 (31%), Positives = 47/129 (36%), Gaps = 27/129 (20%) Query: 415 PTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPG-KGAAPY----APPAPSR 469 P RGL G Q P P P+ P G PG+ L G +PG +G + PP P Sbjct: 787 PGERGLPGPQG-PNGFPGPKGPP--GPPGKDGLPG----HPGQRGEVGFQGKTGPPGPPG 839 Query: 470 SALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAA----GPLGA 525 + G GAAG P GPPG LPG GP GA Sbjct: 840 -----------VVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGA 888 Query: 526 APDRFPADL 534 PA L Sbjct: 889 PGKDGPAGL 897 Score = 30.8 bits (68), Expect = 3.6 Identities = 22/65 (33%), Positives = 26/65 (40%), Gaps = 1/65 (1%) Query: 140 GASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRAPSSSFVLRGSPAP 199 G G G G R GLPG + GL + G PPGV + P S +G P P Sbjct: 503 GERGDDGEIGPR-GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP 561 Query: 200 RADGG 204 G Sbjct: 562 PGQQG 566 Score = 30.0 bits (66), Expect = 6.2 Identities = 38/135 (28%), Positives = 43/135 (31%), Gaps = 43/135 (31%) Query: 417 ARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAA----PYAPPAPSRSAL 472 ARGL G+ P GP G G+ GA KG + P+ PP Sbjct: 741 ARGLSGKS-----GPRGERGPT-GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG--- 791 Query: 473 AHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPG----------------PYA 516 LPG G G P GPPG D LPG P Sbjct: 792 --------LPGPQGPNGFPGPK------GPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP 837 Query: 517 AAAAGPLGAAPDRFP 531 GP GAA + P Sbjct: 838 PGVVGPQGAAGETGP 852 >gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo sapiens] Length = 1629 Score = 50.8 bits (120), Expect = 3e-06 Identities = 43/118 (36%), Positives = 49/118 (41%), Gaps = 25/118 (21%) Query: 415 PTARGLEGRQVVPPPPPAP---RPGPVLGAPGELALAGAAAAYPGKG-AAPYAPPAPSRS 470 P G EG + P PP AP P + G PGE L G A KG P PP P+ S Sbjct: 850 PGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGS 909 Query: 471 ALAHPISLMTLPGEAGAAG----LAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLG 524 PGE GAAG + PPG GPPG +PG GP+G Sbjct: 910 -----------PGERGAAGSGGPIGPPGRPGP-QGPPGAAGEKGVPG-----EKGPIG 950 Score = 45.8 bits (107), Expect = 1e-04 Identities = 42/127 (33%), Positives = 50/127 (39%), Gaps = 24/127 (18%) Query: 415 PTAR-GLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALA 473 PT R G++G +P P P G GE+ G KG + PP P Sbjct: 951 PTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGE--HGPPGPPG---- 1004 Query: 474 HPISLMTLPGEAGAAG----LAPPGHAAA--------FGGPPGGLLLDALPGPYA----A 517 PI + PG AGA G P GH A F GPPG + L LPGP Sbjct: 1005 -PIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGET 1063 Query: 518 AAAGPLG 524 GP+G Sbjct: 1064 GDVGPMG 1070 Score = 40.0 bits (92), Expect = 0.006 Identities = 38/94 (40%), Positives = 41/94 (43%), Gaps = 12/94 (12%) Query: 435 PGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEAGAAGLA-PP 493 PGP G PGE L G A KG P P AP + P L PGE G G A P Sbjct: 838 PGPP-GPPGEQGLPGTAGKEGTKGD-PGPPGAPGKDG---PAGLRGFPGERGLPGTAGGP 892 Query: 494 GHAAAFG--GPPGGLLLDALPGPY-AAAAAGPLG 524 G G GPPG PG AA + GP+G Sbjct: 893 GLKGNEGPSGPPGPA---GSPGERGAAGSGGPIG 923 Score = 39.3 bits (90), Expect = 0.010 Identities = 46/143 (32%), Positives = 55/143 (38%), Gaps = 43/143 (30%) Query: 415 PTARGLEGRQ-VVPPPPPAPRPGP--VLGAPGELALAGAAAAYPGKGA-APYAPP----- 465 P A G G+ V P PA +PGP + G PG + G A G P PP Sbjct: 1234 PGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGL 1293 Query: 466 ---APSRSALAHP--ISLMTLPGEAGAAG----------------LAPPGHAAAF--GGP 502 A ++ HP I L+ PGE G G + PG + GGP Sbjct: 1294 RGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGP 1353 Query: 503 PGGLLLDALPGPYAAAAAGPLGA 525 PG LPGP AGP GA Sbjct: 1354 PG------LPGP-----AGPKGA 1365 Score = 38.9 bits (89), Expect = 0.013 Identities = 39/118 (33%), Positives = 45/118 (38%), Gaps = 14/118 (11%) Query: 417 ARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAA------YPGKGAA--PYAPPAPS 468 A+G G P P +P P G PG L G A + GKGA P A AP Sbjct: 1182 AKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPG 1241 Query: 469 RSALAHPISLMTLPGEAGAAGL----APPGHAAAFG--GPPGGLLLDALPGPYAAAAA 520 ++ P PG G GL G A G GPPG + LPG A A Sbjct: 1242 KTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGA 1299 Score = 34.7 bits (78), Expect = 0.25 Identities = 35/112 (31%), Positives = 41/112 (36%), Gaps = 20/112 (17%) Query: 415 PTARGLEGRQVVPPPPPAPRP-GPV-----LGAPGELALAGAAAAYPGKGA-------AP 461 P +G +G + PP P P GPV GA GE G + KG P Sbjct: 985 PGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGP 1044 Query: 462 YAP------PAPS-RSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGL 506 P P PS + M PG G G A P A GPPGG+ Sbjct: 1045 PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGV 1096 Score = 32.3 bits (72), Expect = 1.3 Identities = 27/85 (31%), Positives = 30/85 (35%), Gaps = 6/85 (7%) Query: 440 GAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAF 499 G PGE G A P P I LPGE+G GL P Sbjct: 458 GLPGEKGHRGDTGAQ----GLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGI 513 Query: 500 GGPPGGLLLDALPGPYAAAAAGPLG 524 GPPG +D GP + GP G Sbjct: 514 PGPPGVRGMDGPQGP--KGSLGPQG 536 Score = 32.0 bits (71), Expect = 1.6 Identities = 35/105 (33%), Positives = 37/105 (35%), Gaps = 23/105 (21%) Query: 430 PPAP-----RPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGE 484 PP P RPGP LG PG L G + P P P L PG+ Sbjct: 381 PPGPMGYTGRPGP-LGQPGSPGLKGESG-----DLGPQGPRGPQ--------GLTGPPGK 426 Query: 485 AGAAGLAPPGHAAAFGGPP---GGLLLDALPG-PYAAAAAGPLGA 525 AG G A A G P G D LPG P G GA Sbjct: 427 AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGA 471 Score = 31.2 bits (69), Expect = 2.8 Identities = 35/137 (25%), Positives = 46/137 (33%), Gaps = 22/137 (16%) Query: 420 LEGRQVVPPPPPAPRPGPVLGAPGELALAGAAA-----AYPGKGAAPYA--PPAPSRSAL 472 LE +V PP P ++G PG G PG+ P + P P ++L Sbjct: 284 LEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSL 343 Query: 473 AHPISLMTLPGEAGAAGLAPPGHA--------AAFGGPPGGLLLDALPGPYA-------A 517 P + G+ G A A A GPPG + PGP Sbjct: 344 MLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLK 403 Query: 518 AAAGPLGAAPDRFPADL 534 +G LG R P L Sbjct: 404 GESGDLGPQGPRGPQGL 420 Score = 31.2 bits (69), Expect = 2.8 Identities = 41/129 (31%), Positives = 47/129 (36%), Gaps = 27/129 (20%) Query: 415 PTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPG-KGAAPY----APPAPSR 469 P RGL G Q P P P+ P G PG+ L G +PG +G + PP P Sbjct: 766 PGERGLPGPQG-PNGFPGPKGPP--GPPGKDGLPG----HPGQRGEVGFQGKTGPPGPPG 818 Query: 470 SALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAA----GPLGA 525 + G GAAG P GPPG LPG GP GA Sbjct: 819 -----------VVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGA 867 Query: 526 APDRFPADL 534 PA L Sbjct: 868 PGKDGPAGL 876 Score = 30.8 bits (68), Expect = 3.6 Identities = 22/65 (33%), Positives = 26/65 (40%), Gaps = 1/65 (1%) Query: 140 GASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRAPSSSFVLRGSPAP 199 G G G G R GLPG + GL + G PPGV + P S +G P P Sbjct: 482 GERGDDGEIGPR-GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP 540 Query: 200 RADGG 204 G Sbjct: 541 PGQQG 545 Score = 30.0 bits (66), Expect = 6.2 Identities = 38/135 (28%), Positives = 43/135 (31%), Gaps = 43/135 (31%) Query: 417 ARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAA----PYAPPAPSRSAL 472 ARGL G+ P GP G G+ GA KG + P+ PP Sbjct: 720 ARGLSGKS-----GPRGERGPT-GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG--- 770 Query: 473 AHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPG----------------PYA 516 LPG G G P GPPG D LPG P Sbjct: 771 --------LPGPQGPNGFPGPK------GPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP 816 Query: 517 AAAAGPLGAAPDRFP 531 GP GAA + P Sbjct: 817 PGVVGPQGAAGETGP 831 >gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo sapiens] Length = 1736 Score = 50.8 bits (120), Expect = 3e-06 Identities = 43/118 (36%), Positives = 49/118 (41%), Gaps = 25/118 (21%) Query: 415 PTARGLEGRQVVPPPPPAP---RPGPVLGAPGELALAGAAAAYPGKG-AAPYAPPAPSRS 470 P G EG + P PP AP P + G PGE L G A KG P PP P+ S Sbjct: 957 PGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGS 1016 Query: 471 ALAHPISLMTLPGEAGAAG----LAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLG 524 PGE GAAG + PPG GPPG +PG GP+G Sbjct: 1017 -----------PGERGAAGSGGPIGPPGRPGP-QGPPGAAGEKGVPG-----EKGPIG 1057 Score = 45.8 bits (107), Expect = 1e-04 Identities = 42/127 (33%), Positives = 50/127 (39%), Gaps = 24/127 (18%) Query: 415 PTAR-GLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALA 473 PT R G++G +P P P G GE+ G KG + PP P Sbjct: 1058 PTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGE--HGPPGPPG---- 1111 Query: 474 HPISLMTLPGEAGAAG----LAPPGHAAA--------FGGPPGGLLLDALPGPYA----A 517 PI + PG AGA G P GH A F GPPG + L LPGP Sbjct: 1112 -PIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGET 1170 Query: 518 AAAGPLG 524 GP+G Sbjct: 1171 GDVGPMG 1177 Score = 40.0 bits (92), Expect = 0.006 Identities = 38/94 (40%), Positives = 41/94 (43%), Gaps = 12/94 (12%) Query: 435 PGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEAGAAGLA-PP 493 PGP G PGE L G A KG P P AP + P L PGE G G A P Sbjct: 945 PGPP-GPPGEQGLPGTAGKEGTKGD-PGPPGAPGKDG---PAGLRGFPGERGLPGTAGGP 999 Query: 494 GHAAAFG--GPPGGLLLDALPGPY-AAAAAGPLG 524 G G GPPG PG AA + GP+G Sbjct: 1000 GLKGNEGPSGPPGPA---GSPGERGAAGSGGPIG 1030 Score = 39.3 bits (90), Expect = 0.010 Identities = 46/143 (32%), Positives = 55/143 (38%), Gaps = 43/143 (30%) Query: 415 PTARGLEGRQ-VVPPPPPAPRPGP--VLGAPGELALAGAAAAYPGKGA-APYAPP----- 465 P A G G+ V P PA +PGP + G PG + G A G P PP Sbjct: 1341 PGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGL 1400 Query: 466 ---APSRSALAHP--ISLMTLPGEAGAAG----------------LAPPGHAAAF--GGP 502 A ++ HP I L+ PGE G G + PG + GGP Sbjct: 1401 RGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGP 1460 Query: 503 PGGLLLDALPGPYAAAAAGPLGA 525 PG LPGP AGP GA Sbjct: 1461 PG------LPGP-----AGPKGA 1472 Score = 38.9 bits (89), Expect = 0.013 Identities = 39/118 (33%), Positives = 45/118 (38%), Gaps = 14/118 (11%) Query: 417 ARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAA------YPGKGAA--PYAPPAPS 468 A+G G P P +P P G PG L G A + GKGA P A AP Sbjct: 1289 AKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPG 1348 Query: 469 RSALAHPISLMTLPGEAGAAGL----APPGHAAAFG--GPPGGLLLDALPGPYAAAAA 520 ++ P PG G GL G A G GPPG + LPG A A Sbjct: 1349 KTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGA 1406 Score = 34.7 bits (78), Expect = 0.25 Identities = 35/112 (31%), Positives = 41/112 (36%), Gaps = 20/112 (17%) Query: 415 PTARGLEGRQVVPPPPPAPRP-GPV-----LGAPGELALAGAAAAYPGKGA-------AP 461 P +G +G + PP P P GPV GA GE G + KG P Sbjct: 1092 PGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGP 1151 Query: 462 YAP------PAPS-RSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGL 506 P P PS + M PG G G A P A GPPGG+ Sbjct: 1152 PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGV 1203 Score = 32.3 bits (72), Expect = 1.3 Identities = 27/85 (31%), Positives = 30/85 (35%), Gaps = 6/85 (7%) Query: 440 GAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAF 499 G PGE G A P P I LPGE+G GL P Sbjct: 565 GLPGEKGHRGDTGAQ----GLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGI 620 Query: 500 GGPPGGLLLDALPGPYAAAAAGPLG 524 GPPG +D GP + GP G Sbjct: 621 PGPPGVRGMDGPQGP--KGSLGPQG 643 Score = 32.0 bits (71), Expect = 1.6 Identities = 35/105 (33%), Positives = 37/105 (35%), Gaps = 23/105 (21%) Query: 430 PPAP-----RPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGE 484 PP P RPGP LG PG L G + P P P L PG+ Sbjct: 488 PPGPMGYTGRPGP-LGQPGSPGLKGESG-----DLGPQGPRGPQ--------GLTGPPGK 533 Query: 485 AGAAGLAPPGHAAAFGGPP---GGLLLDALPG-PYAAAAAGPLGA 525 AG G A A G P G D LPG P G GA Sbjct: 534 AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGA 578 Score = 31.2 bits (69), Expect = 2.8 Identities = 35/137 (25%), Positives = 46/137 (33%), Gaps = 22/137 (16%) Query: 420 LEGRQVVPPPPPAPRPGPVLGAPGELALAGAAA-----AYPGKGAAPYA--PPAPSRSAL 472 LE +V PP P ++G PG G PG+ P + P P ++L Sbjct: 391 LEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSL 450 Query: 473 AHPISLMTLPGEAGAAGLAPPGHA--------AAFGGPPGGLLLDALPGPYA-------A 517 P + G+ G A A A GPPG + PGP Sbjct: 451 MLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLK 510 Query: 518 AAAGPLGAAPDRFPADL 534 +G LG R P L Sbjct: 511 GESGDLGPQGPRGPQGL 527 Score = 31.2 bits (69), Expect = 2.8 Identities = 41/129 (31%), Positives = 47/129 (36%), Gaps = 27/129 (20%) Query: 415 PTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPG-KGAAPY----APPAPSR 469 P RGL G Q P P P+ P G PG+ L G +PG +G + PP P Sbjct: 873 PGERGLPGPQG-PNGFPGPKGPP--GPPGKDGLPG----HPGQRGEVGFQGKTGPPGPPG 925 Query: 470 SALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAA----GPLGA 525 + G GAAG P GPPG LPG GP GA Sbjct: 926 -----------VVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGA 974 Query: 526 APDRFPADL 534 PA L Sbjct: 975 PGKDGPAGL 983 Score = 30.8 bits (68), Expect = 3.6 Identities = 22/65 (33%), Positives = 26/65 (40%), Gaps = 1/65 (1%) Query: 140 GASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRAPSSSFVLRGSPAP 199 G G G G R GLPG + GL + G PPGV + P S +G P P Sbjct: 589 GERGDDGEIGPR-GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP 647 Query: 200 RADGG 204 G Sbjct: 648 PGQQG 652 Score = 30.0 bits (66), Expect = 6.2 Identities = 38/135 (28%), Positives = 43/135 (31%), Gaps = 43/135 (31%) Query: 417 ARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAA----PYAPPAPSRSAL 472 ARGL G+ P GP G G+ GA KG + P+ PP Sbjct: 827 ARGLSGKS-----GPRGERGPT-GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG--- 877 Query: 473 AHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPG----------------PYA 516 LPG G G P GPPG D LPG P Sbjct: 878 --------LPGPQGPNGFPGPK------GPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP 923 Query: 517 AAAAGPLGAAPDRFP 531 GP GAA + P Sbjct: 924 PGVVGPQGAAGETGP 938 >gi|22779860 forkhead box L1 [Homo sapiens] Length = 345 Score = 50.8 bits (120), Expect = 3e-06 Identities = 62/245 (25%), Positives = 95/245 (38%), Gaps = 37/245 (15%) Query: 54 GPERRATAPAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQ 113 GPER A APA L A +A++ ++ + SY LI AI+ AP++R+TL+ Sbjct: 22 GPERPGLPLAFAPAAALAAS----GRAETPQKPPY---SYIALIAMAIQDAPEQRVTLNG 74 Query: 114 IYDWMVRYVPYFKDKGDS-NSSAGWKVGASGWGGGWGRRLGLPGAA-------RCVGLQE 165 IY +++ P++ D +S + + R G PG RC+ + E Sbjct: 75 IYQFIMDRFPFYHDNRQGWQNSIRHNLSLNDCFVKVPREKGRPGKGSYWTLDPRCLDMFE 134 Query: 166 G----RQKEGFLAPPGVTESCSSRAPSSSFVLRGSPAPRADGGGEVTFPEVATCEVVDLG 221 R+K PG E+ RA + P + GG + P ++ + G Sbjct: 135 NGNYRRRKRKPKPGPGAPEAKRPRAETHQRSAEAQPEAGSGAGG--SGPAISRLQAAPAG 192 Query: 222 IGPQARAFSVP--------------LGASLQG-WGTAAGPSPELGSGQGWLPFYPFSTAD 266 P S P G + QG A G + G G G P P S + Sbjct: 193 PSPLLDGPSPPAPLHWPGTASPNEDAGDAAQGAAAVAVGQAARTGDGPG-SPLRPASRSS 251 Query: 267 PSAED 271 P + D Sbjct: 252 PKSSD 256 Score = 31.6 bits (70), Expect = 2.1 Identities = 37/126 (29%), Positives = 46/126 (36%), Gaps = 26/126 (20%) Query: 428 PPPPAPRPGPVLGAP----GELALAGAAAAY---------PGKGAAPYAPPAPSRSALAH 474 P PPAP P +P G+ A AA A PG P + +P S + Sbjct: 200 PSPPAPLHWPGTASPNEDAGDAAQGAAAVAVGQAARTGDGPGSPLRPASRSSPKSSDKSK 259 Query: 475 PISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPD---RFP 531 S+ ++ AG G PP GG A PGP A L A+ F Sbjct: 260 SFSIDSI--LAGKQGQKPPSGDELLGG--------AKPGPGGRLGASLLAASSSLRPPFN 309 Query: 532 ADLDLD 537 A L LD Sbjct: 310 ASLMLD 315 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 50.4 bits (119), Expect = 4e-06 Identities = 43/108 (39%), Positives = 49/108 (45%), Gaps = 14/108 (12%) Query: 425 VVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGE 484 ++P P PA PG V+ P GAAA AP AP P+ A A P + P Sbjct: 225 LLPLPKPA-APGTVIQTP---PFVGAAAP-----PAPAAPSPPAAPAPAAPAAAPPPPPP 275 Query: 485 AGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRFPA 532 A A PPGH A GPP A+P P AA G GAAP PA Sbjct: 276 APATLARPPGHPA---GPP--TAAPAVPPPAAAQNGGSAGAAPAPAPA 318 Score = 44.3 bits (103), Expect = 3e-04 Identities = 41/123 (33%), Positives = 47/123 (38%), Gaps = 10/123 (8%) Query: 414 APTARGLEGRQVVPPPP-PAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSR--- 469 AP A P P PA P P AP LA A P A PPA ++ Sbjct: 248 APPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGG 307 Query: 470 SALAHPISLMTLPGEAGAAGLAPPGHAAAFGGP------PGGLLLDALPGPYAAAAAGPL 523 SA A P G AG +G PG AAA P P ++ A P AA+GP Sbjct: 308 SAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPA 367 Query: 524 GAA 526 A Sbjct: 368 STA 370 Score = 40.0 bits (92), Expect = 0.006 Identities = 43/114 (37%), Positives = 46/114 (40%), Gaps = 15/114 (13%) Query: 425 VVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGE 484 V P PAP GP A G ALA A A PG G P P P A P + TL G Sbjct: 146 VAAGPEPAPA-GPAKPA-GPAALA--ARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGS 201 Query: 485 AGAAG---LAPPGHAAAFGGPPGGLLL--DALPG------PYAAAAAGPLGAAP 527 A A P + GP L L A PG P+ AAA P AAP Sbjct: 202 AALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAP 255 Score = 38.9 bits (89), Expect = 0.013 Identities = 46/141 (32%), Positives = 54/141 (38%), Gaps = 22/141 (15%) Query: 400 VNGDFATHCGDFEKAPTARGLEGRQVVPPPPPAPRPG--------------PVLGAPGEL 445 V+G A G AP A G G PPP RPG P++ P Sbjct: 63 VSGSPAGAAGAGPAAP-AEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLV--PAGP 119 Query: 446 ALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGG 505 A A P +G+A P P+ +A+A P AG A A P AA GP G Sbjct: 120 APPAAKLRPPPEGSAGSCAPVPAAAAVAAGPE----PAPAGPAKPAGPAALAARAGPGPG 175 Query: 506 LLLDALPGPYAAAAAGPLGAA 526 PGP AGP GAA Sbjct: 176 PGPGPGPGPGPGKPAGP-GAA 195 Score = 33.5 bits (75), Expect = 0.56 Identities = 35/115 (30%), Positives = 40/115 (34%), Gaps = 19/115 (16%) Query: 426 VPPPPPA---------PRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPI 476 VPPP A P P P G P + PG GAA A PAP A + Sbjct: 297 VPPPAAAQNGGSAGAAPAPAPAAGGP------AGVSGQPGPGAAA-AAPAPGVKAESPKR 349 Query: 477 SLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRFP 531 + P A + P AA G + ALP P AA P P P Sbjct: 350 VVQAAPPAAQTLAASGPASTAA-SMVIGPTMQGALPSP--AAVPPPAPGTPTGLP 401 Score = 30.0 bits (66), Expect = 6.2 Identities = 32/88 (36%), Positives = 36/88 (40%), Gaps = 11/88 (12%) Query: 443 GELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGE-AGAAGLAPPGHAAAFGG 501 G L AA+A AP P R+A A + + G AGAAG P AA G Sbjct: 27 GSLESQLAASAAHHHHLAPRTPEV--RAAAAGALGNHVVSGSPAGAAGAGP---AAPAEG 81 Query: 502 PPGGLLLDALPGPYAAAAAGPLGAAPDR 529 PG A P P A A P G P R Sbjct: 82 APG-----AAPEPPPAGRARPGGGGPQR 104 >gi|50345831 forkhead box J3 [Homo sapiens] Length = 622 Score = 50.1 bits (118), Expect = 6e-06 Identities = 23/47 (48%), Positives = 32/47 (68%), Gaps = 5/47 (10%) Query: 92 SYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKGDSNSSAGWK 138 SYA LIT AI S+P K++TLS+IY W+ PY+++ G +GWK Sbjct: 82 SYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAG-----SGWK 123 >gi|119508426 alpha 3 type IX collagen [Homo sapiens] Length = 684 Score = 49.3 bits (116), Expect = 1e-05 Identities = 52/176 (29%), Positives = 61/176 (34%), Gaps = 39/176 (22%) Query: 415 PTARGLEGRQVVP--PPPPAPRPGPVL-GAPGELALAGAAAA--YPGKGAAPYAPPAPS- 468 P G++G P P PP P+ P G PGE L G G+ P AP Sbjct: 43 PGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGE 102 Query: 469 RSALAHP----ISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLG 524 R +L P + LPG G AG++ P GPPG L LPGP GP G Sbjct: 103 RGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGP-----PGPPG 157 Query: 525 AAPDRFPADLDLDMFSGSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAP 580 P P + D S PP PPG G P Sbjct: 158 --PPGHPG----------------------VLPEGATDLQCPSICPPGPPGPPGMP 189 Score = 39.3 bits (90), Expect = 0.010 Identities = 34/109 (31%), Positives = 45/109 (41%), Gaps = 10/109 (9%) Query: 414 APTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALA 473 AP RG +G++ P P P + G G+ GAA +G A + P Sbjct: 398 APGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAG-SDGLPGDKGEL 456 Query: 474 HPISLMTLPGEAGAAG-LAPPGHAAAFG--------GPPGGLLLDALPG 513 P L+ GE+G+ G L P G G GPPG L L +PG Sbjct: 457 GPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPG 505 Score = 31.6 bits (70), Expect = 2.1 Identities = 48/168 (28%), Positives = 54/168 (32%), Gaps = 49/168 (29%) Query: 430 PPAPRPGPVLGAPGELALAGAA--AAYPGKGAAPYAPPAPSRSAL---AHPISLMTLPGE 484 P A P +L GEL A A PG P P P + + A P L PG Sbjct: 4 PRACAPLLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGP 63 Query: 485 AGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRFPADLDLDMFSGSLE 544 GA G A G PG L GP GP GA +R GSL Sbjct: 64 KGAPGKPGKPGEAGLPGLPGVDGLTGRDGP-----PGPKGAPGER-----------GSLG 107 Query: 545 CDVESIILNDFMDSDEMDFNFDSALPPPPPGLAG---APPPNQSWVPG 589 PP PPGL G PP ++ V G Sbjct: 108 -------------------------PPGPPGLGGKGLPGPPGEAGVSG 130 >gi|8923842 forkhead box J2 [Homo sapiens] Length = 574 Score = 49.3 bits (116), Expect = 1e-05 Identities = 24/47 (51%), Positives = 31/47 (65%), Gaps = 5/47 (10%) Query: 92 SYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKGDSNSSAGWK 138 SYA LIT AI S+P K++TLS+IY W+ PY+K N+ GWK Sbjct: 70 SYATLITYAINSSPAKKMTLSEIYRWICDNFPYYK-----NAGIGWK 111 >gi|39812378 RAN binding protein 9 [Homo sapiens] Length = 729 Score = 48.1 bits (113), Expect = 2e-05 Identities = 42/128 (32%), Positives = 52/128 (40%), Gaps = 18/128 (14%) Query: 415 PTARGLEGRQVVPPPPPAPRP--GPVLGAPGELALAGAAAAYPGKGAA------------ 460 P + + +Q+ PPPP A P G VL AP ++ + A PG GA Sbjct: 9 PPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAALL 68 Query: 461 --PYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPG--HAAAFGGPPGGLLLDALPGPYA 516 P PP P+ +A P P A A PP AA GP GG AL + Sbjct: 69 LHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTPALVAGSS 128 Query: 517 AAAAGPLG 524 AAA P G Sbjct: 129 AAAPFPHG 136 >gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] Length = 1682 Score = 48.1 bits (113), Expect = 2e-05 Identities = 51/168 (30%), Positives = 58/168 (34%), Gaps = 32/168 (19%) Query: 427 PPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAP----YAPP--APSRSALAHPISLMT 480 PPPPP P PG P +L G + G P APP R +L HP Sbjct: 258 PPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHP----- 312 Query: 481 LPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRFPADLDLDMFS 540 P A A PPGH PPG PGP A G P P DL Sbjct: 313 YPYPAPAYTAHPPGHRLVPAAPPG-------PGPRPPGAESH-GCLPATRPPGSDLR--- 361 Query: 541 GSLECDVESIILNDFMDSDEMDFNFDSAL---PPPPPGLAGAPPPNQS 585 ES + MDS + + P PPGL G + S Sbjct: 362 -------ESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSS 402 Score = 37.0 bits (84), Expect = 0.051 Identities = 28/89 (31%), Positives = 36/89 (40%), Gaps = 7/89 (7%) Query: 415 PTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAH 474 P A+ Q PPPPP P P +L + + L G Y G GAA P P Sbjct: 780 PLAKFPPPSQPQPPPPPPPSPASLLKSLASV-LEGQKYCYRGTGAAVSTRPGPL------ 832 Query: 475 PISLMTLPGEAGAAGLAPPGHAAAFGGPP 503 P + + +GA L P A + G P Sbjct: 833 PTTQYSPGPPSGATALPPTSAAPSAQGSP 861 Score = 30.0 bits (66), Expect = 6.2 Identities = 32/119 (26%), Positives = 43/119 (36%), Gaps = 19/119 (15%) Query: 423 RQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKG-AAPYAPPAPSRSA-LAHPISLMT 480 R + PPPPPA GP A E + +G P PP P R L P S + Sbjct: 475 RLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFS 534 Query: 481 LPGEAGAAGLAPP------------GHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAP 527 + + PP H+++ GP + P PY A + PL P Sbjct: 535 VGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGP-----VSFPPPPYLARSIDPLPRPP 588 >gi|134142824 forkhead box D2 [Homo sapiens] Length = 495 Score = 48.1 bits (113), Expect = 2e-05 Identities = 44/144 (30%), Positives = 55/144 (38%), Gaps = 36/144 (25%) Query: 423 RQVVPPPPPAPRPGPVLGAPGELALAGAAAAY-----------------------PGKGA 459 RQ +PPP P P P P L G A AG A+ P G Sbjct: 225 RQPLPPPHPHPHPHPELLLRGGAAAAGDPGAFLPGFAAYGAYGYGYGLALPAYGAPPPGP 284 Query: 460 APYAPPAP-----SRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGP 514 AP+ P P + +A A P L PG A A PP A+ F G + P P Sbjct: 285 APHPHPHPHAFAFAAAAAAAPCQLSVPPGRAAAPPPGPP-TASVFAG------AGSAPAP 337 Query: 515 YAAAAAGPLGAAPDRFPADLDLDM 538 A+ +GP G P PA L ++ Sbjct: 338 APASGSGP-GPGPAGLPAFLGAEL 360 Score = 46.2 bits (108), Expect = 8e-05 Identities = 92/365 (25%), Positives = 122/365 (33%), Gaps = 99/365 (27%) Query: 31 QPDLAGDED-------------GALGAGVAEGAEDCGPERRATAPAMAPAPPLG--AEVG 75 + DLA DE+ + GA A G+ G A P PP G A Sbjct: 64 EADLAEDEEESGGCSDGEPRALASRGAAAAAGSPGPGAAAARGAAGPGPGPPSGGAATRS 123 Query: 76 PLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKGDS-NSS 134 PL K SY LIT AI +P KRLTLS+I +++ PY+++K + +S Sbjct: 124 PLVKPP---------YSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNS 174 Query: 135 AGWKVGASGWGGGWGRRLGLPGAARCVGLQEG-----------RQKEGFLAPPGVTESCS 183 + + R G PG L R+++ F P + Sbjct: 175 IRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKRQP-LPPPHP 233 Query: 184 SRAPSSSFVLRGSPAPRADGGGEVTFPEVATCEVVDLGIG-------------------- 223 P +LRG A D G P A G G Sbjct: 234 HPHPHPELLLRGGAAAAGDPG--AFLPGFAAYGAYGYGYGLALPAYGAPPPGPAPHPHPH 291 Query: 224 PQARAF-----------SVPLGAS------------LQGWGTAAGPSPELGSGQGWLPFY 260 P A AF SVP G + G G+A P+P GSG G P Sbjct: 292 PHAFAFAAAAAAAPCQLSVPPGRAAAPPPGPPTASVFAGAGSAPAPAPASGSGPGPGP-- 349 Query: 261 PFSTADPSAEDLHMASGPWHHPGHIFCQEEAWTENLNFTPDGRANGLPRA-LNQGLQRTR 319 A P + C + + +L+ G A GLP A L QGL+ Sbjct: 350 --------------AGLPAFLGAELGCAKAFYAASLSPPAAGTAAGLPTALLRQGLKTDA 395 Query: 320 QGKAG 324 G AG Sbjct: 396 GGGAG 400 Score = 42.7 bits (99), Expect = 0.001 Identities = 48/131 (36%), Positives = 50/131 (38%), Gaps = 23/131 (17%) Query: 415 PTARGLEGRQVVPPPPPA----PRPGPVLGAPGEL-ALAGAAAAY-------PGKGAAPY 462 PTA G P P PA P PGP G P L A G A A+ P G A Sbjct: 323 PTASVFAGAGSAPAPAPASGSGPGPGPA-GLPAFLGAELGCAKAFYAASLSPPAAGTAAG 381 Query: 463 APPAPSRSALAHPISLMTLPGEAGAAGLAPP-------GHAAAFGGPPGGLLLDALPGPY 515 P A R L G AG AG P GH PPG + PGP Sbjct: 382 LPTALLRQGLKTDAGGGAGGGGAG-AGQRPSFSIDHIMGHGGGGAAPPGA--GEGSPGPP 438 Query: 516 AAAAAGPLGAA 526 AAAAGP G A Sbjct: 439 FAAAAGPGGQA 449 >gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens] Length = 1712 Score = 47.4 bits (111), Expect = 4e-05 Identities = 45/120 (37%), Positives = 51/120 (42%), Gaps = 12/120 (10%) Query: 418 RGLEGRQVVPPPP--PAPRPGPVL--GAPGELALAGAAAAYPGKGAAPYAP--PAPSRSA 471 RG +G P PP PA P P L GA G+ GA PG P P P P + Sbjct: 334 RGPKGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGE-PGSQGEPGDPGLPGPPGLS 392 Query: 472 LAHPISLMTLPGEAGAAG-LAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRF 530 + LPGE G G + PG A +GGPPG PGP GP G PD F Sbjct: 393 IGDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGP--PGLPGPPG--PDGF 448 Score = 40.8 bits (94), Expect = 0.004 Identities = 38/120 (31%), Positives = 47/120 (39%), Gaps = 24/120 (20%) Query: 428 PPPPAPR---------PGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISL 478 P PP R PGPV G PG+ GA PG+ P +P + P ++ Sbjct: 1222 PGPPGERGDPGEANTLPGPV-GVPGQKGDQGA----PGERGPPGSPGLQGFPGITPPSNI 1276 Query: 479 MTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPG-------PYAAAAAGPLGAAPDRFP 531 PG+ GA G+ + GPPG ALPG P A G G A D P Sbjct: 1277 SGAPGDKGAPGIF---GLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGP 1333 Score = 35.0 bits (79), Expect = 0.19 Identities = 43/142 (30%), Positives = 50/142 (35%), Gaps = 36/142 (25%) Query: 418 RGLEGRQVVPPPPPAPRPGPVLGAPGEL--------ALAG--AAAAYPGKGAAPYAPPAP 467 RG G +P PP P G PG++ A+ G A PG P P Sbjct: 632 RGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLP-- 689 Query: 468 SRSALAHPISLMTLPGEAGAAGL-APPGHAAAFGGP-----PGGLLLDALPGPYAAAAAG 521 L PG GA GL PG A A GGP PG + PGP G Sbjct: 690 ---------GLPGPPGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGP--PGFIG 738 Query: 522 PLGA-------APDRFPADLDL 536 P G+ PD P + L Sbjct: 739 PRGSKGAVGLPGPDGSPGPIGL 760 Score = 33.9 bits (76), Expect = 0.43 Identities = 43/132 (32%), Positives = 48/132 (36%), Gaps = 25/132 (18%) Query: 414 APTARGLEGRQVVPPPPPAPR--PGPVLGA-PGELALAGAAAAYPGKGAAPYAPPAPSRS 470 +P GL G P PP R PG VLGA PG AG KG P R Sbjct: 754 SPGPIGLPG----PDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRG 809 Query: 471 ALAHP-----ISLMTLPGEAGAAGLAPPGHAAAFGGPP---GGLLLDALPG--------- 513 + P LPG +G GL P F G P G L L +PG Sbjct: 810 SQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRG 869 Query: 514 -PYAAAAAGPLG 524 P A GP+G Sbjct: 870 DPGDTGAPGPVG 881 Score = 33.5 bits (75), Expect = 0.56 Identities = 34/106 (32%), Positives = 44/106 (41%), Gaps = 12/106 (11%) Query: 128 KGDS-NSSAGWKVGASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRA 186 KGD+ N A G GW G G + G PG G + R ++GF+ G T + R Sbjct: 1310 KGDTGNPGAPGTPGTKGWAGDSGPQ-GRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRG 1368 Query: 187 PSSSFVLRGSPA-PRADGGGEVTFPEVA----TCEVVDLGIGPQAR 227 P +G P P A G V P +A V +GPQ R Sbjct: 1369 PKGP---KGDPGFPGAP--GTVGAPGIAGIPQKIAVQPGTVGPQGR 1409 Score = 31.6 bits (70), Expect = 2.1 Identities = 36/125 (28%), Positives = 45/125 (36%), Gaps = 16/125 (12%) Query: 419 GLEGRQVVPPPPPAP-RPGP------VLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSA 471 G +G++ P PP P PGP + GA G G + +G + A Sbjct: 426 GPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRC 485 Query: 472 LAHPISLMTLPGEAGAAGLA----PPGHAAAFGGPPGGLLLDALPG----PYAAAAAGPL 523 ++ LPG G G A PG G PG L PG P A GP Sbjct: 486 TEGDEAIKGLPGLPGPKGFAGINGEPGRKGD-RGDPGQHGLPGFPGLKGVPGNIGAPGPK 544 Query: 524 GAAPD 528 GA D Sbjct: 545 GAKGD 549 Score = 31.2 bits (69), Expect = 2.8 Identities = 33/122 (27%), Positives = 38/122 (31%), Gaps = 11/122 (9%) Query: 414 APTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAG--------AAAAYPGKGAAPYAPP 465 A R EG + + P P P G GE G +PG P Sbjct: 480 AGECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIG 539 Query: 466 APSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLD---ALPGPYAAAAAGP 522 AP +T GE G G+ G PG LD LPGP GP Sbjct: 540 APGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGP 599 Query: 523 LG 524 G Sbjct: 600 PG 601 Score = 30.0 bits (66), Expect = 6.2 Identities = 29/95 (30%), Positives = 35/95 (36%), Gaps = 6/95 (6%) Query: 412 EKAPTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGA--AAAYPGKGAAPYAPP-APS 468 +K G G Q PP AP G PGE GA A G+G P Sbjct: 1395 QKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGD 1454 Query: 469 RSALAH--PISLMTLPGEAGAAGL-APPGHAAAFG 500 + H PI PG G+ GL PG + + G Sbjct: 1455 EGPIGHQGPIGQEGAPGRPGSPGLPGMPGRSVSIG 1489 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 46.6 bits (109), Expect = 6e-05 Identities = 43/117 (36%), Positives = 45/117 (38%), Gaps = 22/117 (18%) Query: 415 PTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAH 474 P G +GR P PP A V+G PG AG PGK P P A Sbjct: 556 PGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGE----PGKAGERGVPGPPGAVGPAG 611 Query: 475 PISLMTLPGEAGAAGLAPPGHAAAFG-----GPPGGLLLDALPGPYAAAAAGPLGAA 526 GEAGA G PPG A G GP G LPGP AGP G A Sbjct: 612 K------DGEAGAQG--PPGPAGPAGERGEQGPAGSPGFQGLPGP-----AGPPGEA 655 Score = 45.8 bits (107), Expect = 1e-04 Identities = 109/402 (27%), Positives = 134/402 (33%), Gaps = 93/402 (23%) Query: 140 GASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRAPSSSFVLRGSPAP 199 G +G G G R G PG G R G PG + P+ RGSP P Sbjct: 461 GPAGEEGKRGAR-GEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGE---RGSPGP 516 Query: 200 RADGG--GEVTFPEVATCEVVDLGIGPQARAFSVPLGASLQGWGTAAGPSPELG----SG 253 G GE P A +P L G + GP + G +G Sbjct: 517 AGPKGSPGEAGRPGEA----------------GLPGAKGLTGSPGSPGPDGKTGPPGPAG 560 Query: 254 QGWLPFYPFSTADPSAEDLHMASGPWHHPGHIFCQEEAWTENLNFTPDGRANGLPRALNQ 313 Q P P P A +G PG E P G P A+ Sbjct: 561 QDGRPGPP---GPPGARG---QAGVMGFPGPKGAAGEPGKAGERGVP-----GPPGAVGP 609 Query: 314 GLQRTRQGKAGKSQLLPSKARKCQRQGAWGPEESDQCLELGQYLDQEVEATRTGLAKAGS 373 + G+AG +Q P A +G GP S L EA + G Sbjct: 610 A---GKDGEAG-AQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPG 665 Query: 374 DMGSTGDWHSRIKKRMYGEMAEVFWRVNGDFATHCGDFEKAPTARGLEGRQVVPPPPPAP 433 D+G+ G +R ++ GE RG++G PP P P Sbjct: 666 DLGAPGPSGARGERGFPGE-------------------------RGVQG----PPGPAGP 696 Query: 434 RPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEAGAAGLAPP 493 R GAPG G A A PG AP + AP L +PGE GAAGL P Sbjct: 697 RGAN--GAPGNDGAKGDAGA-PG---APGSQGAPG---------LQGMPGERGAAGLPGP 741 Query: 494 ----GHAAAFG--GPPGGLLLDALPGPYAAAAAGPLGAAPDR 529 G A G G PG + L GP GP GA D+ Sbjct: 742 KGDRGDAGPKGADGSPGKDGVRGLTGP--IGPPGPAGAPGDK 781 Score = 42.7 bits (99), Expect = 0.001 Identities = 44/116 (37%), Positives = 49/116 (42%), Gaps = 13/116 (11%) Query: 418 RGLEGRQVVPPPPPAPRPGPV--LGAPGELALAGAAAAYPGKGAAPYAPPAPSR-----S 470 RGL G + PP PA PG G G GA A PG P PP P+ Sbjct: 763 RGLTGP--IGPPGPAGAPGDKGESGPSGPAGPTGARGA-PGDRGEP-GPPGPAGFAGPPG 818 Query: 471 ALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAA-AAAGPLGA 525 A P PG+AGA G A P A GPPG + PG A +AGP GA Sbjct: 819 ADGQP-GAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGA 873 Score = 40.0 bits (92), Expect = 0.006 Identities = 43/125 (34%), Positives = 45/125 (36%), Gaps = 19/125 (15%) Query: 417 ARGLEGRQVVPPPP-PAPRPGPV-----LGAPGELALAGAAA-AYPGKGAAPYAPPAP-- 467 ARG G + P PP PA GP GA GE AGA A P A P PP P Sbjct: 795 ARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIG 854 Query: 468 --------SRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAA 519 A P PG AG G P A GPPG + GP Sbjct: 855 NVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGP--RGE 912 Query: 520 AGPLG 524 GP G Sbjct: 913 TGPAG 917 Score = 38.1 bits (87), Expect = 0.023 Identities = 31/96 (32%), Positives = 38/96 (39%), Gaps = 14/96 (14%) Query: 431 PAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEAGAAGL 490 PA RPG V G PG AG + PG AP P +A ++ LPG+ G G Sbjct: 915 PAGRPGEV-GPPGPPGPAGEKGS-PGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGF 972 Query: 491 AP------------PGHAAAFGGPPGGLLLDALPGP 514 P A+ GPPG + L GP Sbjct: 973 PGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGP 1008 Score = 37.7 bits (86), Expect = 0.030 Identities = 37/118 (31%), Positives = 40/118 (33%), Gaps = 16/118 (13%) Query: 415 PTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAY--------PGKGAAPYAPPA 466 P G G + +P PP AP P G PGE GA+ PGK Sbjct: 178 PGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGK 237 Query: 467 PSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLG 524 P R P PG GA GL G G LD G A AGP G Sbjct: 238 PGRPGERGP------PGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGD--AGPAGPKG 287 Score = 37.7 bits (86), Expect = 0.030 Identities = 44/125 (35%), Positives = 49/125 (39%), Gaps = 13/125 (10%) Query: 418 RGLEGRQVVP----PPPPAPRPGPV--LGAPGELALAGAAAAYPGKGAAPYAPPAPSRSA 471 RG EG Q V PP PA GP GA G+ GA A PG AP P A S Sbjct: 361 RGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGA-PGIAGAPGFPGARGPSG 419 Query: 472 LAHPISLMTLPGEAGAAGLAPPGHAAAFG--GPPGGLLLDALPGPYAAAAAGPLGAAPDR 529 P G +G G PG G G PG + + PGP A G GA + Sbjct: 420 PQGPGGPPGPKGNSGEPG--APGSKGDTGAKGEPGPVGVQGPPGP--AGEEGKRGARGEP 475 Query: 530 FPADL 534 P L Sbjct: 476 GPTGL 480 Score = 37.7 bits (86), Expect = 0.030 Identities = 112/443 (25%), Positives = 138/443 (31%), Gaps = 84/443 (18%) Query: 127 DKGDSNSSA-GWKVGASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSR 185 DKG+S S GA G G G G PG A GF PPG ++ Sbjct: 780 DKGESGPSGPAGPTGARGAPGDRGEP-GPPGPA------------GFAGPPGADGQPGAK 826 Query: 186 APSSSFVLRGSPAPRADGGGEVTFPEVATCEVVDLGI--GPQARAFSVPLGASLQGWGTA 243 +G P G P + ++G AR + P GA+ G+ A Sbjct: 827 GEPGDAGAKGDAGPPGPAG-----PAGPPGPIGNVGAPGAKGARGSAGPPGAT--GFPGA 879 Query: 244 AGP-SPELGSGQGWLPFYPFSTADPSAEDLHMASGPWHHPGHIFCQEEAWTENLNFTP-- 300 AG P SG P P + +GP PG + +P Sbjct: 880 AGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGA 939 Query: 301 DGRANGLPRALNQGLQRTRQGKAGKSQLLPSKARKCQRQGAWGPEESDQCLELGQYLDQE 360 DG A QG+ R G G LP + + G GP Sbjct: 940 DGPAGAPGTPGPQGIAGQR-GVVG----LPGQRGERGFPGLPGPSG-------------- 980 Query: 361 VEATRTGLAKAGSDMGSTGDWHSRIKKRMYGEMAEVFWRVNGDFATHCGDFEKAPTARGL 420 E + G + A + G G GE R A + +P A+G Sbjct: 981 -EPGKQGPSGASGERGPPGPMGPPGLAGPPGESG----REGAPGAEGSPGRDGSPGAKGD 1035 Query: 421 EGRQVVPPPPPAP----RPGPV-----LGAPGELALAGAAAAYPGKGAAPYAPPAPSR-- 469 G PP AP PGPV G GE AG A GA A P R Sbjct: 1036 RGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGD 1095 Query: 470 ------------------SALAHPISLMTLPGE---AGAAGLAPPGHAAAFGGPPGGLLL 508 S L P PGE +GA+G A P G PG L Sbjct: 1096 KGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGL 1155 Query: 509 DALPGPYAAAAAGPLGAAPDRFP 531 + LPGP GP G D P Sbjct: 1156 NGLPGP--IGPPGPRGRTGDAGP 1176 Score = 37.4 bits (85), Expect = 0.039 Identities = 37/107 (34%), Positives = 42/107 (39%), Gaps = 17/107 (15%) Query: 428 PPPPAPRPGPVLGAPGELALAGA--AAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEA 485 PP P PG + G PGE GA A PG+ +P A + A P PG Sbjct: 996 PPGPMGPPG-LAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGP------PGAP 1048 Query: 486 GAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRFPA 532 GA G P A G G GP A AGP+G R PA Sbjct: 1049 GAPGAPGPVGPAGKSGDRGE------TGP--AGPAGPVGPVGARGPA 1087 Score = 36.6 bits (83), Expect = 0.066 Identities = 44/147 (29%), Positives = 53/147 (36%), Gaps = 26/147 (17%) Query: 418 RGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAA--AAYPGKGAAPYAPPAPSRSALAHP 475 RG G Q P PP G+PGE +GA+ A G + AP + L P Sbjct: 1111 RGFSGLQGPPGPP---------GSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGP 1161 Query: 476 ISLMTLPGEAGAAG----LAPPGHAAAFGGPPGGLLLDALPGPYAAAA--------AGPL 523 I G G AG PPG G P G LP P A A Sbjct: 1162 IGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGGRYYRADDA 1221 Query: 524 GAAPDRFPADLDLDMFSGSLECDVESI 550 DR DL++D SL +E+I Sbjct: 1222 NVVRDR---DLEVDTTLKSLSQQIENI 1245 Score = 36.2 bits (82), Expect = 0.087 Identities = 36/111 (32%), Positives = 40/111 (36%), Gaps = 24/111 (21%) Query: 419 GLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAA-----AYPGKGAAPYAPPAPSRSALA 473 G GR +P P P P G PG L G A Y K + P P Sbjct: 127 GPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGP-----M 181 Query: 474 HPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLG 524 P LPG GA G P G F GPPG P A+GP+G Sbjct: 182 GPSGPRGLPGPPGAPG--PQG----FQGPPG--------EPGEPGASGPMG 218 Score = 35.0 bits (79), Expect = 0.19 Identities = 36/111 (32%), Positives = 38/111 (34%), Gaps = 6/111 (5%) Query: 418 RGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPIS 477 RGL G + P AP P G G AG G P P A A P Sbjct: 304 RGLPGER---GRPGAPGPAGARGNDGATGAAGPPGP-TGPAGPPGFPGAVGAKGEAGPQG 359 Query: 478 LMTLPGEAGAAGL-APPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAP 527 G G G PPG A A GP G D PG A A + AP Sbjct: 360 PRGSEGPQGVRGEPGPPGPAGA-AGPAGNPGADGQPGAKGANGAPGIAGAP 409 Score = 35.0 bits (79), Expect = 0.19 Identities = 39/119 (32%), Positives = 44/119 (36%), Gaps = 13/119 (10%) Query: 415 PTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAA--AAYPGKGAAPYAPPAPSRSAL 472 P A G +G P + P V G PG AGAA A PG P A A + Sbjct: 346 PGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGI 405 Query: 473 AHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRFP 531 A PG GA G P GGPPG PG A + G GA + P Sbjct: 406 A------GAPGFPGARG---PSGPQGPGGPPGPKGNSGEPG--APGSKGDTGAKGEPGP 453 Score = 33.5 bits (75), Expect = 0.56 Identities = 31/112 (27%), Positives = 37/112 (33%), Gaps = 17/112 (15%) Query: 417 ARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPI 476 ARG +G PP P G PG + G A +G+ P Sbjct: 321 ARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGS-------------EGPQ 367 Query: 477 SLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPG----PYAAAAAGPLG 524 + PG G AG A P G PG + PG P A GP G Sbjct: 368 GVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSG 419 Score = 32.3 bits (72), Expect = 1.3 Identities = 37/113 (32%), Positives = 41/113 (36%), Gaps = 17/113 (15%) Query: 427 PPPPPAPRPGP-VLGAPGELALAGAAAAYPGKGAAPYAPP-----APSRSALAHPISLMT 480 PP P R P G PG G + KG A A P +P + + Sbjct: 246 PPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRG 305 Query: 481 LPGEAGAAGLAPPGHAAAFG--------GPPGGLLLDALPG-PYAAAAAGPLG 524 LPGE G G PG A A G GPPG PG P A A G G Sbjct: 306 LPGERGRPG--APGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAG 356 Score = 31.6 bits (70), Expect = 2.1 Identities = 39/111 (35%), Positives = 45/111 (40%), Gaps = 28/111 (25%) Query: 419 GLEGRQV-VPPPPPAPRPGPV--LGAPGELALAGAAAAYPGKGAAPYAP-PAPSRSALAH 474 GL+G + P P PG GAPG++ G PG+ P AP PA +R Sbjct: 272 GLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGL----PGERGRPGAPGPAGARGN--- 324 Query: 475 PISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAA-AAAGPLG 524 G GAAG PPG GPPG PG A AGP G Sbjct: 325 -------DGATGAAG--PPGPTGP-AGPPG------FPGAVGAKGEAGPQG 359 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 46.6 bits (109), Expect = 6e-05 Identities = 40/118 (33%), Positives = 47/118 (39%), Gaps = 12/118 (10%) Query: 417 ARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYP-----GKGAAPYAPPAPSRSA 471 A G G Q +P PP P G G PG+ + G A A G+ P +P Sbjct: 658 APGPSGFQGLPGPPGPPGEG---GKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQG 714 Query: 472 LAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAA-AGPLGAAPD 528 L P L PG G G + P GPPG L +PG AA AGP G D Sbjct: 715 LQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPG---LQGMPGERGAAGIAGPKGDRGD 769 Score = 45.1 bits (105), Expect = 2e-04 Identities = 110/404 (27%), Positives = 134/404 (33%), Gaps = 68/404 (16%) Query: 138 KVGASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRAPSSSFVLRGSP 197 K GA G GG G +G PG G + ++G P G R PS L G Sbjct: 490 KRGARGEPGGVGP-IGPPGERGAPGNRGFPGQDGLAGPKGAP---GERGPSG---LAGPK 542 Query: 198 APRADGG--GEVTFPEVATCEVVDLGIGPQARAFSVPLGASLQGWGTAAGPSPELGSGQG 255 D G GE P GPQ + P GA + G P P+ GQ Sbjct: 543 GANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVG--PSGAPGED-GRPGPPGPQGARGQP 599 Query: 256 WLPFYPFSTADPSAEDLHMASGPWHHPGHIFCQEEAWTENLNFTP--DGR--ANGLPRAL 311 + +P A+G PG + L P DG A G P Sbjct: 600 GVMGFPGPKG---------ANG---EPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPA 647 Query: 312 NQGLQRTRQGKAGKSQLLPSKARKCQRQGAWGPEESDQCLELGQYLDQEV--EATRTGLA 369 +R QG G S QG GP E G+ DQ V EA GL Sbjct: 648 GPAGERGEQGAPGPSGF----------QGLPGPPGPPG--EGGKPGDQGVPGEAGAPGLV 695 Query: 370 KAGSDMGSTGDWHSRIKKRMYGEMAEVFWRVNGDFATHCGDFEKAPTARGLEGRQVVPPP 429 + G G+ S + + G P G +G P Sbjct: 696 GPRGERGFPGERGSPGAQGLQGPRG----------------LPGTPGTDGPKGASGPAGP 739 Query: 430 PPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPP--APSRSALAHPISLMTLPGEAGA 487 P A P + G PGE AG A +G P AP + + PG AGA Sbjct: 740 PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGA 799 Query: 488 AG----LAPPGHAAAFG--GPPGGLLLDALPGPYAAAAAGPLGA 525 G + PPG A + G G PG PGP A AGP GA Sbjct: 800 NGEKGEVGPPGPAGSAGARGAPGERGETGPPGP--AGFAGPPGA 841 Score = 44.7 bits (104), Expect = 2e-04 Identities = 41/119 (34%), Positives = 49/119 (41%), Gaps = 16/119 (13%) Query: 414 APTARGLEGRQ--VVPPPPPAPRPGPVL-GAPGELALAGAAAAYPGKGAA-----PYAPP 465 A ARG +G+ PP P P GP GAPG AG A +GA P P Sbjct: 340 AAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPG 399 Query: 466 APSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLG 524 +P + + +PG G+AG A F GP G PGP A GPLG Sbjct: 400 SPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP------PGP--QGATGPLG 450 Score = 38.5 bits (88), Expect = 0.017 Identities = 42/126 (33%), Positives = 45/126 (35%), Gaps = 26/126 (20%) Query: 415 PTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAG--AAAAYPGKGAAPYAPPA------ 466 P G +G Q P P P GAPG G A PG G P PP Sbjct: 458 PGIAGFKGEQ---GPKGEPGPAGPQGAPGPAGEEGKRGARGEPG-GVGPIGPPGERGAPG 513 Query: 467 ----PSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAA--- 519 P + LA P PGE G +GLA P A G PG LPG Sbjct: 514 NRGFPGQDGLAGPKGA---PGERGPSGLAGPKGANGDPGRPGE---PGLPGARGLTGRPG 567 Query: 520 -AGPLG 524 AGP G Sbjct: 568 DAGPQG 573 Score = 38.1 bits (87), Expect = 0.023 Identities = 42/133 (31%), Positives = 46/133 (34%), Gaps = 29/133 (21%) Query: 414 APTARGLEGRQVVP--PPPPAPRPGPVLGAPGELALAGAAAAYPGKG------------- 458 AP RG +G P P PP P PGP PG L G AA G Sbjct: 145 APGPRGRDGEPGTPGNPGPPGP-PGP----PGPPGLGGNFAAQMAGGFDEKAGGAQLGVM 199 Query: 459 ------AAPYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALP 512 P PP P + P PGE G G++ P GPPG D Sbjct: 200 QGPMGPMGPRGPPGP--AGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEA 257 Query: 513 G-PYAAAAAGPLG 524 G P A GP G Sbjct: 258 GKPGKAGERGPPG 270 Score = 37.4 bits (85), Expect = 0.039 Identities = 42/136 (30%), Positives = 48/136 (35%), Gaps = 30/136 (22%) Query: 414 APTARGLEGRQ--------VVPPPPPAPRPGPV-LGAPGELALAGAAAAYPGKGAAPYAP 464 AP G EG++ V P PP R P G PG+ LAG A +G + A Sbjct: 481 APGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAG 540 Query: 465 PA--------PSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYA 516 P P L L PG+AG G P A G PG PGP Sbjct: 541 PKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGP------PGPQG 594 Query: 517 AAA-------AGPLGA 525 A GP GA Sbjct: 595 ARGQPGVMGFPGPKGA 610 Score = 37.4 bits (85), Expect = 0.039 Identities = 38/117 (32%), Positives = 41/117 (35%), Gaps = 11/117 (9%) Query: 414 APTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALA 473 AP RGL G+ A PGP G GE GA PG P P Sbjct: 625 APGLRGLPGKD--GETGAAGPPGPA-GPAGERGEQGA----PGPSGFQGLPGPPGPPGEG 677 Query: 474 HPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAA----GPLGAA 526 +PGEAGA GL P F G G L GP GP GA+ Sbjct: 678 GKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGAS 734 Score = 37.0 bits (84), Expect = 0.051 Identities = 36/114 (31%), Positives = 42/114 (36%), Gaps = 14/114 (12%) Query: 417 ARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKG----AAPYAPPAPSRSAL 472 A G++G P +P P G PGE G A A +G P PP P Sbjct: 304 APGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGP----- 358 Query: 473 AHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAA 526 P PG GA G A P A GP G PG + GP GA+ Sbjct: 359 VGPAGGPGFPGAPGAKGEAGPTGAR---GPEGAQGPRGEPG--TPGSPGPAGAS 407 Score = 37.0 bits (84), Expect = 0.051 Identities = 113/446 (25%), Positives = 143/446 (32%), Gaps = 90/446 (20%) Query: 140 GASGWGGGWGRR--LGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRA------PSSSF 191 GA+G G G R +G G G GR G + PPG + + P+ S Sbjct: 756 GAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSA 815 Query: 192 VLRGSPAPRADGG--GEVTFPEVATCEVVDLGIGPQARAFSVPLGASLQGWGTAAGPSPE 249 RG+P R + G G F + G Q A + G + P P+ Sbjct: 816 GARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQ 875 Query: 250 LGSGQGWLPFYPFSTADPSAEDLHMASGPWHHPGHIFCQEEAWTENLNFTPDGRANGLPR 309 +G + P A A+G PG N N P G P Sbjct: 876 GPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPG----------SNGNPGPPGP----PG 921 Query: 310 ALNQGLQRTRQGKAGKSQLLPSKARKCQRQGAWGPEESDQCLELGQYLDQEVEATR---- 365 + + +G +G P +A + QG GP E G+ D Sbjct: 922 PSGKDGPKGARGDSGP----PGRAGEPGLQGPAGPPG-----EKGEPGDDGPSGAEGPPG 972 Query: 366 -TGLAKAGSDMGSTGDWHSRIKKRMYGEMAEVFWRVNGDFATHCGDFEKAPTARGLEGRQ 424 GLA +G G R + G E + AP A G G Sbjct: 973 PQGLAGQRGIVGLPGQRGERGFPGLPGPSGEP-------------GKQGAPGASGDRGPP 1019 Query: 425 VVPPPP----PAPRPGPV--LGAPGELALAGAAAAYPGKG-----AAPYAPPAPSRSALA 473 PP PA PG GA G GAA +G AP AP P A Sbjct: 1020 GPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPA 1079 Query: 474 HPISLMTLPGEAGAAG-LAPPGHAAAFG--GPPG--------------GLL-------LD 509 P GEAGA G + P G A A G GP G GL L Sbjct: 1080 GPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQ 1139 Query: 510 ALPGPYAAA----AAGPLGAAPDRFP 531 LPGP + A+GP G + R P Sbjct: 1140 GLPGPPGPSGDQGASGPAGPSGPRGP 1165 Score = 36.6 bits (83), Expect = 0.066 Identities = 34/115 (29%), Positives = 40/115 (34%), Gaps = 3/115 (2%) Query: 415 PTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAH 474 P G G + P PP P G PG+ G +G P P P Sbjct: 233 PGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGF-PGTPGLPGVKGHRG 291 Query: 475 PISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDR 529 L GEAGA G+ + G PG + LPG GP GAA R Sbjct: 292 YPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPG--ERGRTGPAGAAGAR 344 Score = 35.0 bits (79), Expect = 0.19 Identities = 47/155 (30%), Positives = 55/155 (35%), Gaps = 41/155 (26%) Query: 415 PTARGLEGR--------QVVP---------PPPPAPR-----------PGPV-----LGA 441 P ARGL GR +V P P PP P+ PGP G Sbjct: 557 PGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGK 616 Query: 442 PGELALAGAAA--AYPGKGAAPYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAF 499 GE L GA PGK A P + A PG +G GL P Sbjct: 617 AGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGE 676 Query: 500 GGPPGGLLLDALPGPYAAAAAGPLGAAPDR-FPAD 533 GG PG +PG A A G +G +R FP + Sbjct: 677 GGKPGD---QGVPG--EAGAPGLVGPRGERGFPGE 706 Score = 34.7 bits (78), Expect = 0.25 Identities = 28/79 (35%), Positives = 31/79 (39%), Gaps = 9/79 (11%) Query: 428 PPPPAPRPGP--VLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEA 485 PP PA PGP G PGE G + +G P P P A PG+A Sbjct: 211 PPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGP-PGPPGKPGDDGEAGK------PGKA 263 Query: 486 GAAGLAPPGHAAAFGGPPG 504 G G P A F G PG Sbjct: 264 GERGPPGPQGARGFPGTPG 282 Score = 34.7 bits (78), Expect = 0.25 Identities = 45/132 (34%), Positives = 50/132 (37%), Gaps = 28/132 (21%) Query: 417 ARGLEGRQVVPPP--PPAPR--PGPV--LGAPGELALAGAAAAYPGKG----AAPYAPPA 466 A G+ G P P PP P+ GP+ G GE +AG KG A P P Sbjct: 424 APGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPG 483 Query: 467 PSRSALAHPISLMTLPGEAGAAG-LAPPGHAAAFG--GPPGGLLLDALPGPYAA------ 517 P A GE G G + PPG A G G PG D L GP A Sbjct: 484 P-----AGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPG---QDGLAGPKGAPGERGP 535 Query: 518 -AAAGPLGAAPD 528 AGP GA D Sbjct: 536 SGLAGPKGANGD 547 Score = 33.5 bits (75), Expect = 0.56 Identities = 36/116 (31%), Positives = 42/116 (36%), Gaps = 19/116 (16%) Query: 418 RGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPI- 476 RG G Q +P PP G G+ +G A P P P PS A+ I Sbjct: 1133 RGFTGLQGLPGPP---------GPSGDQGASGPAG--PSGPRGPPGPVGPSGKDGANGIP 1181 Query: 477 SLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGP----YAAAAAGPLGAAPD 528 + PG G +G P GPPG PGP A A GP PD Sbjct: 1182 GPIGPPGPRGRSGETGPAGPPGNPGPPGP---PGPPGPGIDMSAFAGLGPREKGPD 1234 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 46.6 bits (109), Expect = 6e-05 Identities = 40/118 (33%), Positives = 47/118 (39%), Gaps = 12/118 (10%) Query: 417 ARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYP-----GKGAAPYAPPAPSRSA 471 A G G Q +P PP P G G PG+ + G A A G+ P +P Sbjct: 589 APGPSGFQGLPGPPGPPGEG---GKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQG 645 Query: 472 LAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAA-AGPLGAAPD 528 L P L PG G G + P GPPG L +PG AA AGP G D Sbjct: 646 LQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPG---LQGMPGERGAAGIAGPKGDRGD 700 Score = 45.1 bits (105), Expect = 2e-04 Identities = 110/404 (27%), Positives = 134/404 (33%), Gaps = 68/404 (16%) Query: 138 KVGASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRAPSSSFVLRGSP 197 K GA G GG G +G PG G + ++G P G R PS L G Sbjct: 421 KRGARGEPGGVGP-IGPPGERGAPGNRGFPGQDGLAGPKGAP---GERGPSG---LAGPK 473 Query: 198 APRADGG--GEVTFPEVATCEVVDLGIGPQARAFSVPLGASLQGWGTAAGPSPELGSGQG 255 D G GE P GPQ + P GA + G P P+ GQ Sbjct: 474 GANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVG--PSGAPGED-GRPGPPGPQGARGQP 530 Query: 256 WLPFYPFSTADPSAEDLHMASGPWHHPGHIFCQEEAWTENLNFTP--DGR--ANGLPRAL 311 + +P A+G PG + L P DG A G P Sbjct: 531 GVMGFPGPKG---------ANG---EPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPA 578 Query: 312 NQGLQRTRQGKAGKSQLLPSKARKCQRQGAWGPEESDQCLELGQYLDQEV--EATRTGLA 369 +R QG G S QG GP E G+ DQ V EA GL Sbjct: 579 GPAGERGEQGAPGPSGF----------QGLPGPPGPPG--EGGKPGDQGVPGEAGAPGLV 626 Query: 370 KAGSDMGSTGDWHSRIKKRMYGEMAEVFWRVNGDFATHCGDFEKAPTARGLEGRQVVPPP 429 + G G+ S + + G P G +G P Sbjct: 627 GPRGERGFPGERGSPGAQGLQGPRG----------------LPGTPGTDGPKGASGPAGP 670 Query: 430 PPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPP--APSRSALAHPISLMTLPGEAGA 487 P A P + G PGE AG A +G P AP + + PG AGA Sbjct: 671 PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGA 730 Query: 488 AG----LAPPGHAAAFG--GPPGGLLLDALPGPYAAAAAGPLGA 525 G + PPG A + G G PG PGP A AGP GA Sbjct: 731 NGEKGEVGPPGPAGSAGARGAPGERGETGPPGP--AGFAGPPGA 772 Score = 44.7 bits (104), Expect = 2e-04 Identities = 41/119 (34%), Positives = 49/119 (41%), Gaps = 16/119 (13%) Query: 414 APTARGLEGRQ--VVPPPPPAPRPGPVL-GAPGELALAGAAAAYPGKGAA-----PYAPP 465 A ARG +G+ PP P P GP GAPG AG A +GA P P Sbjct: 271 AAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPG 330 Query: 466 APSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLG 524 +P + + +PG G+AG A F GP G PGP A GPLG Sbjct: 331 SPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP------PGP--QGATGPLG 381 Score = 38.5 bits (88), Expect = 0.017 Identities = 42/126 (33%), Positives = 45/126 (35%), Gaps = 26/126 (20%) Query: 415 PTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAG--AAAAYPGKGAAPYAPPA------ 466 P G +G Q P P P GAPG G A PG G P PP Sbjct: 389 PGIAGFKGEQ---GPKGEPGPAGPQGAPGPAGEEGKRGARGEPG-GVGPIGPPGERGAPG 444 Query: 467 ----PSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAA--- 519 P + LA P PGE G +GLA P A G PG LPG Sbjct: 445 NRGFPGQDGLAGPKGA---PGERGPSGLAGPKGANGDPGRPGE---PGLPGARGLTGRPG 498 Query: 520 -AGPLG 524 AGP G Sbjct: 499 DAGPQG 504 Score = 38.1 bits (87), Expect = 0.023 Identities = 42/133 (31%), Positives = 46/133 (34%), Gaps = 29/133 (21%) Query: 414 APTARGLEGRQVVP--PPPPAPRPGPVLGAPGELALAGAAAAYPGKG------------- 458 AP RG +G P P PP P PGP PG L G AA G Sbjct: 76 APGPRGRDGEPGTPGNPGPPGP-PGP----PGPPGLGGNFAAQMAGGFDEKAGGAQLGVM 130 Query: 459 ------AAPYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALP 512 P PP P + P PGE G G++ P GPPG D Sbjct: 131 QGPMGPMGPRGPPGP--AGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEA 188 Query: 513 G-PYAAAAAGPLG 524 G P A GP G Sbjct: 189 GKPGKAGERGPPG 201 Score = 37.4 bits (85), Expect = 0.039 Identities = 42/136 (30%), Positives = 48/136 (35%), Gaps = 30/136 (22%) Query: 414 APTARGLEGRQ--------VVPPPPPAPRPGPV-LGAPGELALAGAAAAYPGKGAAPYAP 464 AP G EG++ V P PP R P G PG+ LAG A +G + A Sbjct: 412 APGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAG 471 Query: 465 PA--------PSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYA 516 P P L L PG+AG G P A G PG PGP Sbjct: 472 PKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGP------PGPQG 525 Query: 517 AAA-------AGPLGA 525 A GP GA Sbjct: 526 ARGQPGVMGFPGPKGA 541 Score = 37.4 bits (85), Expect = 0.039 Identities = 38/117 (32%), Positives = 41/117 (35%), Gaps = 11/117 (9%) Query: 414 APTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALA 473 AP RGL G+ A PGP G GE GA PG P P Sbjct: 556 APGLRGLPGKD--GETGAAGPPGPA-GPAGERGEQGA----PGPSGFQGLPGPPGPPGEG 608 Query: 474 HPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAA----GPLGAA 526 +PGEAGA GL P F G G L GP GP GA+ Sbjct: 609 GKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGAS 665 Score = 37.0 bits (84), Expect = 0.051 Identities = 36/114 (31%), Positives = 42/114 (36%), Gaps = 14/114 (12%) Query: 417 ARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKG----AAPYAPPAPSRSAL 472 A G++G P +P P G PGE G A A +G P PP P Sbjct: 235 APGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGP----- 289 Query: 473 AHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAA 526 P PG GA G A P A GP G PG + GP GA+ Sbjct: 290 VGPAGGPGFPGAPGAKGEAGPTGAR---GPEGAQGPRGEPG--TPGSPGPAGAS 338 Score = 37.0 bits (84), Expect = 0.051 Identities = 113/446 (25%), Positives = 143/446 (32%), Gaps = 90/446 (20%) Query: 140 GASGWGGGWGRR--LGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRA------PSSSF 191 GA+G G G R +G G G GR G + PPG + + P+ S Sbjct: 687 GAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSA 746 Query: 192 VLRGSPAPRADGG--GEVTFPEVATCEVVDLGIGPQARAFSVPLGASLQGWGTAAGPSPE 249 RG+P R + G G F + G Q A + G + P P+ Sbjct: 747 GARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQ 806 Query: 250 LGSGQGWLPFYPFSTADPSAEDLHMASGPWHHPGHIFCQEEAWTENLNFTPDGRANGLPR 309 +G + P A A+G PG N N P G P Sbjct: 807 GPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPG----------SNGNPGPPGP----PG 852 Query: 310 ALNQGLQRTRQGKAGKSQLLPSKARKCQRQGAWGPEESDQCLELGQYLDQEVEATR---- 365 + + +G +G P +A + QG GP E G+ D Sbjct: 853 PSGKDGPKGARGDSGP----PGRAGEPGLQGPAGPPG-----EKGEPGDDGPSGAEGPPG 903 Query: 366 -TGLAKAGSDMGSTGDWHSRIKKRMYGEMAEVFWRVNGDFATHCGDFEKAPTARGLEGRQ 424 GLA +G G R + G E + AP A G G Sbjct: 904 PQGLAGQRGIVGLPGQRGERGFPGLPGPSGEP-------------GKQGAPGASGDRGPP 950 Query: 425 VVPPPP----PAPRPGPV--LGAPGELALAGAAAAYPGKG-----AAPYAPPAPSRSALA 473 PP PA PG GA G GAA +G AP AP P A Sbjct: 951 GPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPA 1010 Query: 474 HPISLMTLPGEAGAAG-LAPPGHAAAFG--GPPG--------------GLL-------LD 509 P GEAGA G + P G A A G GP G GL L Sbjct: 1011 GPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQ 1070 Query: 510 ALPGPYAAA----AAGPLGAAPDRFP 531 LPGP + A+GP G + R P Sbjct: 1071 GLPGPPGPSGDQGASGPAGPSGPRGP 1096 Score = 36.6 bits (83), Expect = 0.066 Identities = 34/115 (29%), Positives = 40/115 (34%), Gaps = 3/115 (2%) Query: 415 PTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAH 474 P G G + P PP P G PG+ G +G P P P Sbjct: 164 PGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGF-PGTPGLPGVKGHRG 222 Query: 475 PISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDR 529 L GEAGA G+ + G PG + LPG GP GAA R Sbjct: 223 YPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPG--ERGRTGPAGAAGAR 275 Score = 35.0 bits (79), Expect = 0.19 Identities = 47/155 (30%), Positives = 55/155 (35%), Gaps = 41/155 (26%) Query: 415 PTARGLEGR--------QVVP---------PPPPAPR-----------PGPV-----LGA 441 P ARGL GR +V P P PP P+ PGP G Sbjct: 488 PGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGK 547 Query: 442 PGELALAGAAA--AYPGKGAAPYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAF 499 GE L GA PGK A P + A PG +G GL P Sbjct: 548 AGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGE 607 Query: 500 GGPPGGLLLDALPGPYAAAAAGPLGAAPDR-FPAD 533 GG PG +PG A A G +G +R FP + Sbjct: 608 GGKPGD---QGVPG--EAGAPGLVGPRGERGFPGE 637 Score = 34.7 bits (78), Expect = 0.25 Identities = 28/79 (35%), Positives = 31/79 (39%), Gaps = 9/79 (11%) Query: 428 PPPPAPRPGP--VLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEA 485 PP PA PGP G PGE G + +G P P P A PG+A Sbjct: 142 PPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGP-PGPPGKPGDDGEAGK------PGKA 194 Query: 486 GAAGLAPPGHAAAFGGPPG 504 G G P A F G PG Sbjct: 195 GERGPPGPQGARGFPGTPG 213 Score = 34.7 bits (78), Expect = 0.25 Identities = 45/132 (34%), Positives = 50/132 (37%), Gaps = 28/132 (21%) Query: 417 ARGLEGRQVVPPP--PPAPR--PGPV--LGAPGELALAGAAAAYPGKG----AAPYAPPA 466 A G+ G P P PP P+ GP+ G GE +AG KG A P P Sbjct: 355 APGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPG 414 Query: 467 PSRSALAHPISLMTLPGEAGAAG-LAPPGHAAAFG--GPPGGLLLDALPGPYAA------ 517 P A GE G G + PPG A G G PG D L GP A Sbjct: 415 P-----AGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPG---QDGLAGPKGAPGERGP 466 Query: 518 -AAAGPLGAAPD 528 AGP GA D Sbjct: 467 SGLAGPKGANGD 478 Score = 33.5 bits (75), Expect = 0.56 Identities = 36/116 (31%), Positives = 42/116 (36%), Gaps = 19/116 (16%) Query: 418 RGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPI- 476 RG G Q +P PP G G+ +G A P P P PS A+ I Sbjct: 1064 RGFTGLQGLPGPP---------GPSGDQGASGPAG--PSGPRGPPGPVGPSGKDGANGIP 1112 Query: 477 SLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGP----YAAAAAGPLGAAPD 528 + PG G +G P GPPG PGP A A GP PD Sbjct: 1113 GPIGPPGPRGRSGETGPAGPPGNPGPPGP---PGPPGPGIDMSAFAGLGPREKGPD 1165 >gi|160707881 formin 2 [Homo sapiens] Length = 1722 Score = 46.6 bits (109), Expect = 6e-05 Identities = 53/179 (29%), Positives = 65/179 (36%), Gaps = 42/179 (23%) Query: 415 PTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAH 474 P L+G +++PPPPP P PG + P L AG P GA PP +A+ Sbjct: 897 PQPPPLQGTEMLPPPPP-PLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPP 955 Query: 475 PISL----MTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDA-LPGPYAAAAAG-----PLG 524 P L + LP AG+ PP G PP L A +P P AG PL Sbjct: 956 PPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1015 Query: 525 AAPDRFPADLDLDMFSGSLECDVESIILNDFMDSDEMDFNFDSALPPPPP-GLAGAPPP 582 A P L + +PPPPP AG PPP Sbjct: 1016 GAGIPPPPPLP------------------------------GAGIPPPPPLPGAGIPPP 1044 Score = 37.4 bits (85), Expect = 0.039 Identities = 49/162 (30%), Positives = 54/162 (33%), Gaps = 46/162 (28%) Query: 429 PPPAPRPGPVLGAPGELALAGAAAAYPGKGAA-PYAPPAPSRSALAHPISLMTLPGEAGA 487 PPP P PG + P L AG P GA P PP P P LPG Sbjct: 976 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP----PLPG---- 1027 Query: 488 AGLAPPGHAAAFGGPPGGLLLDA-LPGPYAAAAAG-----PLGAAPDRFPADLDLDMFSG 541 AG+ PP G PP L A +P P AG PL A P L Sbjct: 1028 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP------ 1081 Query: 542 SLECDVESIILNDFMDSDEMDFNFDSALPPPPP-GLAGAPPP 582 + +PPPPP AG PPP Sbjct: 1082 ------------------------GAGIPPPPPLPGAGIPPP 1099 Score = 36.6 bits (83), Expect = 0.066 Identities = 35/98 (35%), Positives = 39/98 (39%), Gaps = 12/98 (12%) Query: 426 VPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAA-PYAPPAPSRSALAHPISLMTLPGE 484 +PPPPP P G + P L AG P GA P PP P P LPG Sbjct: 1008 IPPPPPLPGAG--IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP----PLPG- 1060 Query: 485 AGAAGLAPPGHAAAFGGPPGGLLLDA-LPGPYAAAAAG 521 AG+ PP G PP L A +P P AG Sbjct: 1061 ---AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1095 Score = 36.6 bits (83), Expect = 0.066 Identities = 33/98 (33%), Positives = 36/98 (36%), Gaps = 17/98 (17%) Query: 415 PTARGLEGRQVVPPPP--------PAPRPGPVLGAPGELALAGAAAAYPGKGAA-PYAPP 465 P L G + PPPP P P PG + P L AG P GA P PP Sbjct: 1009 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1068 Query: 466 APSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPP 503 P P LPG AG+ PP G PP Sbjct: 1069 LPGAGIPPPP----PLPG----AGIPPPPPLPGAGIPP 1098 Score = 36.6 bits (83), Expect = 0.066 Identities = 32/97 (32%), Positives = 36/97 (37%), Gaps = 15/97 (15%) Query: 415 PTARGLEGRQVVPPPP--------PAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPA 466 P L G + PPPP P P PG + P L AG P GA PP Sbjct: 1086 PPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1145 Query: 467 PSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPP 503 R + P LPG AG+ PP G PP Sbjct: 1146 LPRVGIPPP---PPLPG----AGIPPPPPLPGAGIPP 1175 Score = 35.8 bits (81), Expect = 0.11 Identities = 33/98 (33%), Positives = 36/98 (36%), Gaps = 17/98 (17%) Query: 415 PTARGLEGRQVVPPPP--------PAPRPGPVLGAPGELALAGAAAAYPGKGAA-PYAPP 465 P L G + PPPP P P PG + P L AG P GA P PP Sbjct: 1042 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1101 Query: 466 APSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPP 503 P P LPG AG+ PP G PP Sbjct: 1102 LPGVGIPPPP----PLPG----AGIPPPPPLPGAGIPP 1131 Score = 35.8 bits (81), Expect = 0.11 Identities = 35/108 (32%), Positives = 38/108 (35%), Gaps = 20/108 (18%) Query: 426 VPPPPPAPR---------PGPVLGAPGELALAGAAAAYPGKGAA-PYAPPAPSRSALAHP 475 +PPPPP PR PG + P L AG P G P PP P P Sbjct: 1140 IPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPP 1199 Query: 476 ISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPL 523 LPG AG+ PP G PP LP P PL Sbjct: 1200 ----PLPG----AGIPPPPPLPGMGIPPAP--APPLPPPGTGIPPPPL 1237 Score = 34.7 bits (78), Expect = 0.25 Identities = 51/183 (27%), Positives = 58/183 (31%), Gaps = 64/183 (34%) Query: 416 TARGLEGRQVVPPPPPAPRPG------PVLGAPGELALAGA------AAAYPGKGAAPYA 463 ++ + G +VPPPPP P PG P P L G PG G P Sbjct: 866 SSSSMPGLGMVPPPPP-PLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPP-P 923 Query: 464 PPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDA---LPGPYAAAAA 520 PP P L P LPG AG+ PP PP L A LP P A Sbjct: 924 PPLPGAGILPLP----PLPG----AGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGI 975 Query: 521 GPLGAAPDRFPADLDLDMFSGSLECDVESIILNDFMDSDEMDFNFDSALPPPPP-GLAGA 579 P P P + +PPPPP AG Sbjct: 976 PP----PPPLPG----------------------------------AGIPPPPPLPGAGI 997 Query: 580 PPP 582 PPP Sbjct: 998 PPP 1000 Score = 32.0 bits (71), Expect = 1.6 Identities = 27/91 (29%), Positives = 32/91 (35%), Gaps = 10/91 (10%) Query: 415 PTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAH 474 P + E R+ P PP+P PV AP A AA P A P+ P A Sbjct: 280 PESLAAEPRE--PQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGA 337 Query: 475 PISLMTLPGEAGAAGLAPPGHAAAFGGPPGG 505 P+ GA G AF P G Sbjct: 338 PV--------RGAGDTDEEGEEDAFEDAPRG 360 Score = 31.6 bits (70), Expect = 2.1 Identities = 32/105 (30%), Positives = 39/105 (37%), Gaps = 17/105 (16%) Query: 415 PTARGLEGRQVVPPPP--------PAPRPGPVLGAPGELALAG--AAAAYPGKGAAPY-A 463 P L G + PPPP P P PG + P L AG PG G P A Sbjct: 1163 PPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPA 1222 Query: 464 PPAPSRSALAHPISLMTLPG-----EAGAAGLAPPGHAAAFGGPP 503 PP P P L+ + G + G++ L P F PP Sbjct: 1223 PPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTP-QVCGFLPPP 1266 >gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo sapiens] Length = 1130 Score = 46.6 bits (109), Expect = 6e-05 Identities = 50/175 (28%), Positives = 66/175 (37%), Gaps = 33/175 (18%) Query: 425 VVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGE 484 V PP P+P P PG + G + P G P A P PS + P + P Sbjct: 651 VPPPEAPSPFRAPPFHPPGPMPSVG---SMPSAGPMPSAGPMPSAGPV--PSARPGPPTT 705 Query: 485 AGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAA-------GPLGAAPDRFPADLDLD 537 A GL+ PG + PP LPGP A P G P P D + Sbjct: 706 ANHLGLSVPGLVSV---PP-----RLLPGPENHRAGSNEDPILAPSGTPPPTIPPD---E 754 Query: 538 MFSGSL---------ECDVESIILNDFMDSDEMDFNFDSALPP-PPPGLAGAPPP 582 F G + + + + ++ DSD+ LPP PPP +GA PP Sbjct: 755 TFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPP 809 Score = 46.2 bits (108), Expect = 8e-05 Identities = 53/175 (30%), Positives = 64/175 (36%), Gaps = 37/175 (21%) Query: 428 PPPPAPRP--GPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEA 485 PPP AP P P PG + G+ P G P A P PS + P + P A Sbjct: 652 PPPEAPSPFRAPPFHPPGPMPSVGSM---PSAGPMPSAGPMPSAGPV--PSARPGPPTTA 706 Query: 486 GAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAG-------PLGAAPDRFPADLDLDM 538 GL+ PG + PP LPGP A P G P P D + Sbjct: 707 NHLGLSVPGLVSV---PPR-----LLPGPENHRAGSNEDPILAPSGTPPPTIPPD---ET 755 Query: 539 FSGSLE------------CDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPP 581 F G + DVE + +D DS + LPPPPP A PP Sbjct: 756 FGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPP 810 Score = 34.3 bits (77), Expect = 0.33 Identities = 17/35 (48%), Positives = 18/35 (51%), Gaps = 4/35 (11%) Query: 427 PPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAP 461 PPPPP P PGPV P +L G PG G P Sbjct: 842 PPPPPPPVPGPVTLPPPQLVPEGT----PGGGGPP 872 >gi|24497506 forkhead box A3 [Homo sapiens] Length = 350 Score = 46.6 bits (109), Expect = 6e-05 Identities = 39/118 (33%), Positives = 49/118 (41%), Gaps = 17/118 (14%) Query: 16 FAPQSRPRSCTWPLPQPDLAGDEDGAL------GAGVAEGAEDCGPERRATAPAMAPAPP 69 + P P S PLP LA A G GV+ G+ G P Sbjct: 50 YPPGGLPAS---PLPSGPLAPPAPAAPLGPTFPGLGVSGGSSSSGYGAPGPGLVHGKEMP 106 Query: 70 LGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKD 127 G PL AK SY LIT AI+ AP K LTLS+IY W++ PY+++ Sbjct: 107 KGYR-RPLAHAKPP-------YSYISLITMAIQQAPGKMLTLSEIYQWIMDLFPYYRE 156 >gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo sapiens] Length = 1818 Score = 46.2 bits (108), Expect = 8e-05 Identities = 45/124 (36%), Positives = 51/124 (41%), Gaps = 14/124 (11%) Query: 415 PTARGLEGRQVVPPPPP-APRPGP--VLGAPGELALAGAAAAYPGK--GAAPYAPPAPSR 469 P A G EG + P P + + GP + G PGE L GA A PG G P PP P Sbjct: 1011 PGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA-PGLKGGEGPQGPPGPVG 1069 Query: 470 S-------ALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYA-AAAAG 521 S A PI L PG G G A A GP G D + GP AG Sbjct: 1070 SPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAG 1129 Query: 522 PLGA 525 P G+ Sbjct: 1130 PAGS 1133 Score = 40.8 bits (94), Expect = 0.004 Identities = 41/132 (31%), Positives = 48/132 (36%), Gaps = 25/132 (18%) Query: 412 EKAPTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGA----APYAPPAP 467 EK P +G GR V P P P G+PGE G KG+ PP P Sbjct: 1106 EKGP--QGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGP 1163 Query: 468 SRSALAHPISLMTLPGEAGAAGLAPPGHAAAFG-----------GPPGGLLLDALPGPYA 516 L P+ + G G G P G FG GPPG + L LPGP Sbjct: 1164 P--GLQGPVGAPGIAGGDGEPG--PRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1219 Query: 517 AAA----AGPLG 524 GP+G Sbjct: 1220 EKGENGDVGPMG 1231 Score = 40.0 bits (92), Expect = 0.006 Identities = 40/112 (35%), Positives = 44/112 (39%), Gaps = 19/112 (16%) Query: 425 VVPPPPPAPRPGPV--------LGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPI 476 VV P P GP+ G PGE L GAA GK A P S P Sbjct: 980 VVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA----GKEGAKGDPGPQGISGKDGPA 1035 Query: 477 SLMTLPGEAGAAGL-APPGHAAAFG--GPPGGLLLDALPGPY-AAAAAGPLG 524 L PGE G G PG G GPPG + PG +A AGP+G Sbjct: 1036 GLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPV---GSPGERGSAGTAGPIG 1084 Score = 35.8 bits (81), Expect = 0.11 Identities = 38/119 (31%), Positives = 42/119 (35%), Gaps = 27/119 (22%) Query: 418 RGLEGRQVVPPPPPAPRPGPV--------LGAPGELALAG-----AAAAYPG-KG----A 459 RG++G PP P +PG G PGE G PG KG Sbjct: 576 RGVQG-----PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGER 630 Query: 460 APYAPPAP----SRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGP 514 P PP P I LPGEAG GL P G PG +D PGP Sbjct: 631 GPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGP 689 Score = 34.3 bits (77), Expect = 0.33 Identities = 50/173 (28%), Positives = 61/173 (35%), Gaps = 40/173 (23%) Query: 427 PPPPPAPRPGPVLGAPGELALAGAA----AAYPGKGAAPYAPPAPSRSALAHPISLMT-L 481 P PP GP G P E + + AY KG A+ P L+ Sbjct: 405 PTSPPNEEFGP--GVPAETDITETSINGHGAYGEKGQK-------GEPAVVEPGMLVEGP 455 Query: 482 PGEAGAAG-LAPPGHAAAFG--------GPPG--GLL-LDALPGPYAAAAAGPLGAAPDR 529 PG AG AG + PPG G GPPG GL D LPGP G + P R Sbjct: 456 PGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGP-----PGTMLMLPFR 510 Query: 530 FPADLDLDMFSGSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPP 582 + D + E ++I+ PP P GL G P P Sbjct: 511 YGGDGSKGPTISAQEAQAQAIL---------QQARIALRGPPGPMGLTGRPGP 554 Score = 33.9 bits (76), Expect = 0.43 Identities = 51/170 (30%), Positives = 57/170 (33%), Gaps = 64/170 (37%) Query: 415 PTARGLEGRQ-------------------VVPPPPPAPRPGP-----VLGAPGELALAGA 450 P A G EGRQ V P PA +PGP + G GE L GA Sbjct: 1377 PGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGA 1436 Query: 451 AAAYPGKGAAPYAPPA--------PSRSALAHP--ISLMT------------LPGEAGAA 488 A G P PP S+ HP I L+ LPG G+ Sbjct: 1437 AGQDGPPG--PMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSP 1494 Query: 489 GL----APPGHAAAFG--GPPGGLLLDALPGPYA----AAAAGPLGAAPD 528 G PG A G GPPG LPGP + GP G D Sbjct: 1495 GAKGDGGIPGPAGPLGPPGPPG------LPGPQGPKGNKGSTGPAGQKGD 1538 Score = 33.1 bits (74), Expect = 0.73 Identities = 35/121 (28%), Positives = 38/121 (31%), Gaps = 22/121 (18%) Query: 418 RGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPIS 477 RGL G + P P P V G PG G G+ P P L P Sbjct: 663 RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQ----GEPGPPGQQGNPGPQGLPGPQG 718 Query: 478 LMTLPGEAGAAGL----------APPGHAAAFG--------GPPGGLLLDALPGPYAAAA 519 + PGE G G PPGH G GPPG PGP Sbjct: 719 PIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKG 778 Query: 520 A 520 A Sbjct: 779 A 779 Score = 33.1 bits (74), Expect = 0.73 Identities = 51/177 (28%), Positives = 57/177 (32%), Gaps = 44/177 (24%) Query: 427 PPPPPAPR-PGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEA 485 PP PP PR P GA G G+ + G G GE Sbjct: 1232 PPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK----------------------GEP 1269 Query: 486 GAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAA----AAGPLG-------AAPDRFPADL 534 G AG P A GGP G GP AA A GP G P FP D Sbjct: 1270 GEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDP 1329 Query: 535 DLDMFSGSLECDVESIILNDFMDSDE-MDFNFDSALPPPPPGLAGAP-PPNQSWVPG 589 G D + D+ D + PP P G AG P PP + PG Sbjct: 1330 GPPGEPGPAG--------QDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPG 1378 Score = 32.3 bits (72), Expect = 1.3 Identities = 106/414 (25%), Positives = 134/414 (32%), Gaps = 80/414 (19%) Query: 138 KVGASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRAPSSSFVLRGSP 197 K G G G G R G+PG G + R +G PG R P +G P Sbjct: 587 KPGKRGRPGADGGR-GMPGEP---GAKGDRGFDGLPGLPGDKGHRGERGP------QGPP 636 Query: 198 APRADGG-----GEVTFPEVATCEVVDLGI-GPQARAFSVPLGASLQGWGTAAGPSPELG 251 P D G GE+ P E G+ GP+ P + G GP +G Sbjct: 637 GPPGDDGMRGEDGEIG-PRGLPGEAGPRGLLGPRGTP-GAPGQPGMAGVDGPPGPKGNMG 694 Query: 252 SGQGWLPFYPFSTADPSAEDLHMASGPWHHPGHIFCQEEAWTENLNFTPDGRAN--GLPR 309 QG P P +P + L GP PG P G+ GLP Sbjct: 695 P-QGE-PGPPGQQGNPGPQGLPGPQGPIGPPGEK-------------GPQGKPGLAGLPG 739 Query: 310 ALNQGLQRTRQGKAGKSQLL--PSKARKCQRQGAWGPEESDQCLELGQYLDQEVEATRTG 367 A ++G++G+ L P G G + +D L + E G Sbjct: 740 ADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLK---GSKGEKGEDG 796 Query: 368 LAKAGSDMGSTGDWHSRIKKRMYGEMAEVFWRVNGDFATHCGDFEKAPTA-------RGL 420 DMG GD GE+ ++ R G+ PT G Sbjct: 797 FPGFKGDMGLKGD---------RGEVGQIGPR--GEDGPEGPKGRAGPTGDPGPSGQAGE 845 Query: 421 EGRQVVPPPPPAP-RPGP--------VLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSA 471 +G+ VP P P R GP GA GE G A +G P SR A Sbjct: 846 KGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGA 905 Query: 472 LAHPISLMTLPGEAGAAGL-APPGHAAAFG-----------GPPGGLLLDALPG 513 P G +G G PPG G GPPG D LPG Sbjct: 906 RG-PTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPG 958 Score = 32.0 bits (71), Expect = 1.6 Identities = 26/78 (33%), Positives = 31/78 (39%), Gaps = 2/78 (2%) Query: 128 KGDSNSSA-GWKVGASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRA 186 KGD K G +G G G R GLPGA GL+ G +G P G S Sbjct: 1020 KGDPGPQGISGKDGPAGLRGFPGER-GLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAG 1078 Query: 187 PSSSFVLRGSPAPRADGG 204 + L G P P+ G Sbjct: 1079 TAGPIGLPGRPGPQGPPG 1096 Score = 30.4 bits (67), Expect = 4.8 Identities = 43/166 (25%), Positives = 55/166 (33%), Gaps = 24/166 (14%) Query: 415 PTARGLEGRQVVPPPPPAPRPGPVL----------GAPGELALAGAAAAYPGKG-----A 459 P A G +G PP P P P L G PG + L G KG Sbjct: 1434 PGAAGQDG----PPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1489 Query: 460 APYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAA 519 +P A + P + PG G G P GP G LPGP + Sbjct: 1490 TQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP--PGS 1547 Query: 520 AGPLGAAPDRFP--ADLDLDMFSGSLECDVESIILNDFMDSDEMDF 563 GP G P + + ++ D + IL D+ D E F Sbjct: 1548 PGPPGEVIQPLPILSSKKTRRHTEGMQADADDNIL-DYSDGMEEIF 1592 Score = 30.0 bits (66), Expect = 6.2 Identities = 32/107 (29%), Positives = 37/107 (34%), Gaps = 6/107 (5%) Query: 418 RGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPIS 477 +G G + PP A P G PG+ G PG P P P A Sbjct: 1287 KGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN----PGPVGFPGDPGPPGEPGPAGQDG 1342 Query: 478 LMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLG 524 + GE G G P + GPPG PG AA A G G Sbjct: 1343 VGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPG--AAGAEGRQG 1387 >gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo sapiens] Length = 1767 Score = 46.2 bits (108), Expect = 8e-05 Identities = 45/124 (36%), Positives = 51/124 (41%), Gaps = 14/124 (11%) Query: 415 PTARGLEGRQVVPPPPP-APRPGP--VLGAPGELALAGAAAAYPGK--GAAPYAPPAPSR 469 P A G EG + P P + + GP + G PGE L GA A PG G P PP P Sbjct: 960 PGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA-PGLKGGEGPQGPPGPVG 1018 Query: 470 S-------ALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYA-AAAAG 521 S A PI L PG G G A A GP G D + GP AG Sbjct: 1019 SPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAG 1078 Query: 522 PLGA 525 P G+ Sbjct: 1079 PAGS 1082 Score = 40.8 bits (94), Expect = 0.004 Identities = 41/132 (31%), Positives = 48/132 (36%), Gaps = 25/132 (18%) Query: 412 EKAPTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGA----APYAPPAP 467 EK P +G GR V P P P G+PGE G KG+ PP P Sbjct: 1055 EKGP--QGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGP 1112 Query: 468 SRSALAHPISLMTLPGEAGAAGLAPPGHAAAFG-----------GPPGGLLLDALPGPYA 516 L P+ + G G G P G FG GPPG + L LPGP Sbjct: 1113 P--GLQGPVGAPGIAGGDGEPG--PRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1168 Query: 517 AAA----AGPLG 524 GP+G Sbjct: 1169 EKGENGDVGPMG 1180 Score = 40.0 bits (92), Expect = 0.006 Identities = 40/112 (35%), Positives = 44/112 (39%), Gaps = 19/112 (16%) Query: 425 VVPPPPPAPRPGPV--------LGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPI 476 VV P P GP+ G PGE L GAA GK A P S P Sbjct: 929 VVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA----GKEGAKGDPGPQGISGKDGPA 984 Query: 477 SLMTLPGEAGAAGL-APPGHAAAFG--GPPGGLLLDALPGPY-AAAAAGPLG 524 L PGE G G PG G GPPG + PG +A AGP+G Sbjct: 985 GLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPV---GSPGERGSAGTAGPIG 1033 Score = 35.8 bits (81), Expect = 0.11 Identities = 38/119 (31%), Positives = 42/119 (35%), Gaps = 27/119 (22%) Query: 418 RGLEGRQVVPPPPPAPRPGPV--------LGAPGELALAG-----AAAAYPG-KG----A 459 RG++G PP P +PG G PGE G PG KG Sbjct: 525 RGVQG-----PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGER 579 Query: 460 APYAPPAP----SRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGP 514 P PP P I LPGEAG GL P G PG +D PGP Sbjct: 580 GPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGP 638 Score = 34.3 bits (77), Expect = 0.33 Identities = 50/173 (28%), Positives = 61/173 (35%), Gaps = 40/173 (23%) Query: 427 PPPPPAPRPGPVLGAPGELALAGAA----AAYPGKGAAPYAPPAPSRSALAHPISLMT-L 481 P PP GP G P E + + AY KG A+ P L+ Sbjct: 354 PTSPPNEEFGP--GVPAETDITETSINGHGAYGEKGQK-------GEPAVVEPGMLVEGP 404 Query: 482 PGEAGAAG-LAPPGHAAAFG--------GPPG--GLL-LDALPGPYAAAAAGPLGAAPDR 529 PG AG AG + PPG G GPPG GL D LPGP G + P R Sbjct: 405 PGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGP-----PGTMLMLPFR 459 Query: 530 FPADLDLDMFSGSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPP 582 + D + E ++I+ PP P GL G P P Sbjct: 460 YGGDGSKGPTISAQEAQAQAIL---------QQARIALRGPPGPMGLTGRPGP 503 Score = 33.9 bits (76), Expect = 0.43 Identities = 51/170 (30%), Positives = 57/170 (33%), Gaps = 64/170 (37%) Query: 415 PTARGLEGRQ-------------------VVPPPPPAPRPGP-----VLGAPGELALAGA 450 P A G EGRQ V P PA +PGP + G GE L GA Sbjct: 1326 PGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGA 1385 Query: 451 AAAYPGKGAAPYAPPA--------PSRSALAHP--ISLMT------------LPGEAGAA 488 A G P PP S+ HP I L+ LPG G+ Sbjct: 1386 AGQDGPPG--PMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSP 1443 Query: 489 GL----APPGHAAAFG--GPPGGLLLDALPGPYA----AAAAGPLGAAPD 528 G PG A G GPPG LPGP + GP G D Sbjct: 1444 GAKGDGGIPGPAGPLGPPGPPG------LPGPQGPKGNKGSTGPAGQKGD 1487 Score = 33.1 bits (74), Expect = 0.73 Identities = 35/121 (28%), Positives = 38/121 (31%), Gaps = 22/121 (18%) Query: 418 RGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPIS 477 RGL G + P P P V G PG G G+ P P L P Sbjct: 612 RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQ----GEPGPPGQQGNPGPQGLPGPQG 667 Query: 478 LMTLPGEAGAAGL----------APPGHAAAFG--------GPPGGLLLDALPGPYAAAA 519 + PGE G G PPGH G GPPG PGP Sbjct: 668 PIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKG 727 Query: 520 A 520 A Sbjct: 728 A 728 Score = 33.1 bits (74), Expect = 0.73 Identities = 51/177 (28%), Positives = 57/177 (32%), Gaps = 44/177 (24%) Query: 427 PPPPPAPR-PGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEA 485 PP PP PR P GA G G+ + G G GE Sbjct: 1181 PPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK----------------------GEP 1218 Query: 486 GAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAA----AAGPLG-------AAPDRFPADL 534 G AG P A GGP G GP AA A GP G P FP D Sbjct: 1219 GEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDP 1278 Query: 535 DLDMFSGSLECDVESIILNDFMDSDE-MDFNFDSALPPPPPGLAGAP-PPNQSWVPG 589 G D + D+ D + PP P G AG P PP + PG Sbjct: 1279 GPPGEPGPAG--------QDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPG 1327 Score = 32.3 bits (72), Expect = 1.3 Identities = 106/414 (25%), Positives = 134/414 (32%), Gaps = 80/414 (19%) Query: 138 KVGASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRAPSSSFVLRGSP 197 K G G G G R G+PG G + R +G PG R P +G P Sbjct: 536 KPGKRGRPGADGGR-GMPGEP---GAKGDRGFDGLPGLPGDKGHRGERGP------QGPP 585 Query: 198 APRADGG-----GEVTFPEVATCEVVDLGI-GPQARAFSVPLGASLQGWGTAAGPSPELG 251 P D G GE+ P E G+ GP+ P + G GP +G Sbjct: 586 GPPGDDGMRGEDGEIG-PRGLPGEAGPRGLLGPRGTP-GAPGQPGMAGVDGPPGPKGNMG 643 Query: 252 SGQGWLPFYPFSTADPSAEDLHMASGPWHHPGHIFCQEEAWTENLNFTPDGRAN--GLPR 309 QG P P +P + L GP PG P G+ GLP Sbjct: 644 P-QGE-PGPPGQQGNPGPQGLPGPQGPIGPPGEK-------------GPQGKPGLAGLPG 688 Query: 310 ALNQGLQRTRQGKAGKSQLL--PSKARKCQRQGAWGPEESDQCLELGQYLDQEVEATRTG 367 A ++G++G+ L P G G + +D L + E G Sbjct: 689 ADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLK---GSKGEKGEDG 745 Query: 368 LAKAGSDMGSTGDWHSRIKKRMYGEMAEVFWRVNGDFATHCGDFEKAPTA-------RGL 420 DMG GD GE+ ++ R G+ PT G Sbjct: 746 FPGFKGDMGLKGD---------RGEVGQIGPR--GEDGPEGPKGRAGPTGDPGPSGQAGE 794 Query: 421 EGRQVVPPPPPAP-RPGP--------VLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSA 471 +G+ VP P P R GP GA GE G A +G P SR A Sbjct: 795 KGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGA 854 Query: 472 LAHPISLMTLPGEAGAAGL-APPGHAAAFG-----------GPPGGLLLDALPG 513 P G +G G PPG G GPPG D LPG Sbjct: 855 RG-PTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPG 907 Score = 32.0 bits (71), Expect = 1.6 Identities = 26/78 (33%), Positives = 31/78 (39%), Gaps = 2/78 (2%) Query: 128 KGDSNSSA-GWKVGASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRA 186 KGD K G +G G G R GLPGA GL+ G +G P G S Sbjct: 969 KGDPGPQGISGKDGPAGLRGFPGER-GLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAG 1027 Query: 187 PSSSFVLRGSPAPRADGG 204 + L G P P+ G Sbjct: 1028 TAGPIGLPGRPGPQGPPG 1045 Score = 30.4 bits (67), Expect = 4.8 Identities = 43/166 (25%), Positives = 55/166 (33%), Gaps = 24/166 (14%) Query: 415 PTARGLEGRQVVPPPPPAPRPGPVL----------GAPGELALAGAAAAYPGKG-----A 459 P A G +G PP P P P L G PG + L G KG Sbjct: 1383 PGAAGQDG----PPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1438 Query: 460 APYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAA 519 +P A + P + PG G G P GP G LPGP + Sbjct: 1439 TQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP--PGS 1496 Query: 520 AGPLGAAPDRFP--ADLDLDMFSGSLECDVESIILNDFMDSDEMDF 563 GP G P + + ++ D + IL D+ D E F Sbjct: 1497 PGPPGEVIQPLPILSSKKTRRHTEGMQADADDNIL-DYSDGMEEIF 1541 Score = 30.0 bits (66), Expect = 6.2 Identities = 32/107 (29%), Positives = 37/107 (34%), Gaps = 6/107 (5%) Query: 418 RGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPIS 477 +G G + PP A P G PG+ G PG P P P A Sbjct: 1236 KGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN----PGPVGFPGDPGPPGEPGPAGQDG 1291 Query: 478 LMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLG 524 + GE G G P + GPPG PG AA A G G Sbjct: 1292 VGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPG--AAGAEGRQG 1336 >gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo sapiens] Length = 1806 Score = 46.2 bits (108), Expect = 8e-05 Identities = 45/124 (36%), Positives = 51/124 (41%), Gaps = 14/124 (11%) Query: 415 PTARGLEGRQVVPPPPP-APRPGP--VLGAPGELALAGAAAAYPGK--GAAPYAPPAPSR 469 P A G EG + P P + + GP + G PGE L GA A PG G P PP P Sbjct: 999 PGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA-PGLKGGEGPQGPPGPVG 1057 Query: 470 S-------ALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYA-AAAAG 521 S A PI L PG G G A A GP G D + GP AG Sbjct: 1058 SPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAG 1117 Query: 522 PLGA 525 P G+ Sbjct: 1118 PAGS 1121 Score = 40.8 bits (94), Expect = 0.004 Identities = 41/132 (31%), Positives = 48/132 (36%), Gaps = 25/132 (18%) Query: 412 EKAPTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGA----APYAPPAP 467 EK P +G GR V P P P G+PGE G KG+ PP P Sbjct: 1094 EKGP--QGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGP 1151 Query: 468 SRSALAHPISLMTLPGEAGAAGLAPPGHAAAFG-----------GPPGGLLLDALPGPYA 516 L P+ + G G G P G FG GPPG + L LPGP Sbjct: 1152 P--GLQGPVGAPGIAGGDGEPG--PRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1207 Query: 517 AAA----AGPLG 524 GP+G Sbjct: 1208 EKGENGDVGPMG 1219 Score = 40.0 bits (92), Expect = 0.006 Identities = 40/112 (35%), Positives = 44/112 (39%), Gaps = 19/112 (16%) Query: 425 VVPPPPPAPRPGPV--------LGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPI 476 VV P P GP+ G PGE L GAA GK A P S P Sbjct: 968 VVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA----GKEGAKGDPGPQGISGKDGPA 1023 Query: 477 SLMTLPGEAGAAGL-APPGHAAAFG--GPPGGLLLDALPGPY-AAAAAGPLG 524 L PGE G G PG G GPPG + PG +A AGP+G Sbjct: 1024 GLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPV---GSPGERGSAGTAGPIG 1072 Score = 35.8 bits (81), Expect = 0.11 Identities = 38/119 (31%), Positives = 42/119 (35%), Gaps = 27/119 (22%) Query: 418 RGLEGRQVVPPPPPAPRPGPV--------LGAPGELALAG-----AAAAYPG-KG----A 459 RG++G PP P +PG G PGE G PG KG Sbjct: 564 RGVQG-----PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGER 618 Query: 460 APYAPPAP----SRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGP 514 P PP P I LPGEAG GL P G PG +D PGP Sbjct: 619 GPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGP 677 Score = 34.3 bits (77), Expect = 0.33 Identities = 50/173 (28%), Positives = 61/173 (35%), Gaps = 40/173 (23%) Query: 427 PPPPPAPRPGPVLGAPGELALAGAA----AAYPGKGAAPYAPPAPSRSALAHPISLMT-L 481 P PP GP G P E + + AY KG A+ P L+ Sbjct: 393 PTSPPNEEFGP--GVPAETDITETSINGHGAYGEKGQK-------GEPAVVEPGMLVEGP 443 Query: 482 PGEAGAAG-LAPPGHAAAFG--------GPPG--GLL-LDALPGPYAAAAAGPLGAAPDR 529 PG AG AG + PPG G GPPG GL D LPGP G + P R Sbjct: 444 PGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGP-----PGTMLMLPFR 498 Query: 530 FPADLDLDMFSGSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPP 582 + D + E ++I+ PP P GL G P P Sbjct: 499 YGGDGSKGPTISAQEAQAQAIL---------QQARIALRGPPGPMGLTGRPGP 542 Score = 33.9 bits (76), Expect = 0.43 Identities = 51/170 (30%), Positives = 57/170 (33%), Gaps = 64/170 (37%) Query: 415 PTARGLEGRQ-------------------VVPPPPPAPRPGP-----VLGAPGELALAGA 450 P A G EGRQ V P PA +PGP + G GE L GA Sbjct: 1365 PGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGA 1424 Query: 451 AAAYPGKGAAPYAPPA--------PSRSALAHP--ISLMT------------LPGEAGAA 488 A G P PP S+ HP I L+ LPG G+ Sbjct: 1425 AGQDGPPG--PMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSP 1482 Query: 489 GL----APPGHAAAFG--GPPGGLLLDALPGPYA----AAAAGPLGAAPD 528 G PG A G GPPG LPGP + GP G D Sbjct: 1483 GAKGDGGIPGPAGPLGPPGPPG------LPGPQGPKGNKGSTGPAGQKGD 1526 Score = 33.1 bits (74), Expect = 0.73 Identities = 35/121 (28%), Positives = 38/121 (31%), Gaps = 22/121 (18%) Query: 418 RGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPIS 477 RGL G + P P P V G PG G G+ P P L P Sbjct: 651 RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQ----GEPGPPGQQGNPGPQGLPGPQG 706 Query: 478 LMTLPGEAGAAGL----------APPGHAAAFG--------GPPGGLLLDALPGPYAAAA 519 + PGE G G PPGH G GPPG PGP Sbjct: 707 PIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKG 766 Query: 520 A 520 A Sbjct: 767 A 767 Score = 33.1 bits (74), Expect = 0.73 Identities = 51/177 (28%), Positives = 57/177 (32%), Gaps = 44/177 (24%) Query: 427 PPPPPAPR-PGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEA 485 PP PP PR P GA G G+ + G G GE Sbjct: 1220 PPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK----------------------GEP 1257 Query: 486 GAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAA----AAGPLG-------AAPDRFPADL 534 G AG P A GGP G GP AA A GP G P FP D Sbjct: 1258 GEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDP 1317 Query: 535 DLDMFSGSLECDVESIILNDFMDSDE-MDFNFDSALPPPPPGLAGAP-PPNQSWVPG 589 G D + D+ D + PP P G AG P PP + PG Sbjct: 1318 GPPGEPGPAG--------QDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPG 1366 Score = 32.3 bits (72), Expect = 1.3 Identities = 106/414 (25%), Positives = 134/414 (32%), Gaps = 80/414 (19%) Query: 138 KVGASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRAPSSSFVLRGSP 197 K G G G G R G+PG G + R +G PG R P +G P Sbjct: 575 KPGKRGRPGADGGR-GMPGEP---GAKGDRGFDGLPGLPGDKGHRGERGP------QGPP 624 Query: 198 APRADGG-----GEVTFPEVATCEVVDLGI-GPQARAFSVPLGASLQGWGTAAGPSPELG 251 P D G GE+ P E G+ GP+ P + G GP +G Sbjct: 625 GPPGDDGMRGEDGEIG-PRGLPGEAGPRGLLGPRGTP-GAPGQPGMAGVDGPPGPKGNMG 682 Query: 252 SGQGWLPFYPFSTADPSAEDLHMASGPWHHPGHIFCQEEAWTENLNFTPDGRAN--GLPR 309 QG P P +P + L GP PG P G+ GLP Sbjct: 683 P-QGE-PGPPGQQGNPGPQGLPGPQGPIGPPGEK-------------GPQGKPGLAGLPG 727 Query: 310 ALNQGLQRTRQGKAGKSQLL--PSKARKCQRQGAWGPEESDQCLELGQYLDQEVEATRTG 367 A ++G++G+ L P G G + +D L + E G Sbjct: 728 ADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLK---GSKGEKGEDG 784 Query: 368 LAKAGSDMGSTGDWHSRIKKRMYGEMAEVFWRVNGDFATHCGDFEKAPTA-------RGL 420 DMG GD GE+ ++ R G+ PT G Sbjct: 785 FPGFKGDMGLKGD---------RGEVGQIGPR--GEDGPEGPKGRAGPTGDPGPSGQAGE 833 Query: 421 EGRQVVPPPPPAP-RPGP--------VLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSA 471 +G+ VP P P R GP GA GE G A +G P SR A Sbjct: 834 KGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGA 893 Query: 472 LAHPISLMTLPGEAGAAGL-APPGHAAAFG-----------GPPGGLLLDALPG 513 P G +G G PPG G GPPG D LPG Sbjct: 894 RG-PTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPG 946 Score = 32.0 bits (71), Expect = 1.6 Identities = 26/78 (33%), Positives = 31/78 (39%), Gaps = 2/78 (2%) Query: 128 KGDSNSSA-GWKVGASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRA 186 KGD K G +G G G R GLPGA GL+ G +G P G S Sbjct: 1008 KGDPGPQGISGKDGPAGLRGFPGER-GLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAG 1066 Query: 187 PSSSFVLRGSPAPRADGG 204 + L G P P+ G Sbjct: 1067 TAGPIGLPGRPGPQGPPG 1084 Score = 30.4 bits (67), Expect = 4.8 Identities = 43/166 (25%), Positives = 55/166 (33%), Gaps = 24/166 (14%) Query: 415 PTARGLEGRQVVPPPPPAPRPGPVL----------GAPGELALAGAAAAYPGKG-----A 459 P A G +G PP P P P L G PG + L G KG Sbjct: 1422 PGAAGQDG----PPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1477 Query: 460 APYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAA 519 +P A + P + PG G G P GP G LPGP + Sbjct: 1478 TQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP--PGS 1535 Query: 520 AGPLGAAPDRFP--ADLDLDMFSGSLECDVESIILNDFMDSDEMDF 563 GP G P + + ++ D + IL D+ D E F Sbjct: 1536 PGPPGEVIQPLPILSSKKTRRHTEGMQADADDNIL-DYSDGMEEIF 1580 Score = 30.0 bits (66), Expect = 6.2 Identities = 32/107 (29%), Positives = 37/107 (34%), Gaps = 6/107 (5%) Query: 418 RGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPIS 477 +G G + PP A P G PG+ G PG P P P A Sbjct: 1275 KGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN----PGPVGFPGDPGPPGEPGPAGQDG 1330 Query: 478 LMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLG 524 + GE G G P + GPPG PG AA A G G Sbjct: 1331 VGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPG--AAGAEGRQG 1375 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.135 0.434 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 31,381,065 Number of Sequences: 37866 Number of extensions: 1981270 Number of successful extensions: 18383 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 279 Number of HSP's successfully gapped in prelim test: 786 Number of HSP's that attempted gapping in prelim test: 11210 Number of HSP's gapped (non-prelim): 6094 length of query: 589 length of database: 18,247,518 effective HSP length: 108 effective length of query: 481 effective length of database: 14,157,990 effective search space: 6809993190 effective search space used: 6809993190 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.