Guide to the Human Genome
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Search of human proteins with 239747320

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239747320 PREDICTED: forkhead box protein O6 [Homo sapiens]
         (589 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239747320 PREDICTED: forkhead box protein O6 [Homo sapiens]       1233   0.0  
gi|239741142 PREDICTED: forkhead box protein O6 [Homo sapiens]        337   1e-92
gi|239752748 PREDICTED: similar to forkhead box O6 [Homo sapiens]     279   4e-75
gi|103472003 forkhead box O4 [Homo sapiens]                           190   4e-48
gi|42519916 forkhead box O3A [Homo sapiens]                           145   1e-34
gi|4503739 forkhead box O3A [Homo sapiens]                            145   1e-34
gi|9257222 forkhead box O1 [Homo sapiens]                             141   2e-33
gi|24497501 forkhead box A1 [Homo sapiens]                             57   6e-08
gi|195947376 forkhead box I2 [Homo sapiens]                            54   5e-07
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...    51   3e-06
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    51   3e-06
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    51   3e-06
gi|22779860 forkhead box L1 [Homo sapiens]                             51   3e-06
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    50   4e-06
gi|50345831 forkhead box J3 [Homo sapiens]                             50   6e-06
gi|119508426 alpha 3 type IX collagen [Homo sapiens]                   49   1e-05
gi|8923842 forkhead box J2 [Homo sapiens]                              49   1e-05
gi|39812378 RAN binding protein 9 [Homo sapiens]                       48   2e-05
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]         48   2e-05
gi|134142824 forkhead box D2 [Homo sapiens]                            48   2e-05
gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens]     47   4e-05
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      47   6e-05
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    47   6e-05
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    47   6e-05
gi|160707881 formin 2 [Homo sapiens]                                   47   6e-05
gi|155030232 proline, glutamic acid and leucine rich protein 1 [...    47   6e-05
gi|24497506 forkhead box A3 [Homo sapiens]                             47   6e-05
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    46   8e-05
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    46   8e-05
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    46   8e-05

>gi|239747320 PREDICTED: forkhead box protein O6 [Homo sapiens]
          Length = 589

 Score = 1233 bits (3189), Expect = 0.0
 Identities = 589/589 (100%), Positives = 589/589 (100%)

Query: 1   MAAKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRAT 60
           MAAKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRAT
Sbjct: 1   MAAKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRAT 60

Query: 61  APAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVR 120
           APAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVR
Sbjct: 61  APAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVR 120

Query: 121 YVPYFKDKGDSNSSAGWKVGASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTE 180
           YVPYFKDKGDSNSSAGWKVGASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTE
Sbjct: 121 YVPYFKDKGDSNSSAGWKVGASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTE 180

Query: 181 SCSSRAPSSSFVLRGSPAPRADGGGEVTFPEVATCEVVDLGIGPQARAFSVPLGASLQGW 240
           SCSSRAPSSSFVLRGSPAPRADGGGEVTFPEVATCEVVDLGIGPQARAFSVPLGASLQGW
Sbjct: 181 SCSSRAPSSSFVLRGSPAPRADGGGEVTFPEVATCEVVDLGIGPQARAFSVPLGASLQGW 240

Query: 241 GTAAGPSPELGSGQGWLPFYPFSTADPSAEDLHMASGPWHHPGHIFCQEEAWTENLNFTP 300
           GTAAGPSPELGSGQGWLPFYPFSTADPSAEDLHMASGPWHHPGHIFCQEEAWTENLNFTP
Sbjct: 241 GTAAGPSPELGSGQGWLPFYPFSTADPSAEDLHMASGPWHHPGHIFCQEEAWTENLNFTP 300

Query: 301 DGRANGLPRALNQGLQRTRQGKAGKSQLLPSKARKCQRQGAWGPEESDQCLELGQYLDQE 360
           DGRANGLPRALNQGLQRTRQGKAGKSQLLPSKARKCQRQGAWGPEESDQCLELGQYLDQE
Sbjct: 301 DGRANGLPRALNQGLQRTRQGKAGKSQLLPSKARKCQRQGAWGPEESDQCLELGQYLDQE 360

Query: 361 VEATRTGLAKAGSDMGSTGDWHSRIKKRMYGEMAEVFWRVNGDFATHCGDFEKAPTARGL 420
           VEATRTGLAKAGSDMGSTGDWHSRIKKRMYGEMAEVFWRVNGDFATHCGDFEKAPTARGL
Sbjct: 361 VEATRTGLAKAGSDMGSTGDWHSRIKKRMYGEMAEVFWRVNGDFATHCGDFEKAPTARGL 420

Query: 421 EGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMT 480
           EGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMT
Sbjct: 421 EGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMT 480

Query: 481 LPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRFPADLDLDMFS 540
           LPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRFPADLDLDMFS
Sbjct: 481 LPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRFPADLDLDMFS 540

Query: 541 GSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPPNQSWVPG 589
           GSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPPNQSWVPG
Sbjct: 541 GSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPPNQSWVPG 589


>gi|239741142 PREDICTED: forkhead box protein O6 [Homo sapiens]
          Length = 492

 Score =  337 bits (865), Expect = 1e-92
 Identities = 163/170 (95%), Positives = 164/170 (96%)

Query: 420 LEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLM 479
           L+G Q    P PAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLM
Sbjct: 323 LDGAQDAYGPRPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLM 382

Query: 480 TLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRFPADLDLDMF 539
           TLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRFPADLDLDMF
Sbjct: 383 TLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRFPADLDLDMF 442

Query: 540 SGSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPPNQSWVPG 589
           SGSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPPNQSWVPG
Sbjct: 443 SGSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPPNQSWVPG 492



 Score =  289 bits (739), Expect = 6e-78
 Identities = 138/138 (100%), Positives = 138/138 (100%)

Query: 1   MAAKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRAT 60
           MAAKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRAT
Sbjct: 1   MAAKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRAT 60

Query: 61  APAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVR 120
           APAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVR
Sbjct: 61  APAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVR 120

Query: 121 YVPYFKDKGDSNSSAGWK 138
           YVPYFKDKGDSNSSAGWK
Sbjct: 121 YVPYFKDKGDSNSSAGWK 138


>gi|239752748 PREDICTED: similar to forkhead box O6 [Homo sapiens]
          Length = 562

 Score =  279 bits (714), Expect = 4e-75
 Identities = 134/137 (97%), Positives = 134/137 (97%)

Query: 2   AAKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRATA 61
           AAKLRAH VDVDPDFAPQSRP S TWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRATA
Sbjct: 179 AAKLRAHHVDVDPDFAPQSRPHSSTWPLPQPDLAGDEDGALGAGVAEGAEDCGPERRATA 238

Query: 62  PAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVRY 121
           PAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVRY
Sbjct: 239 PAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVRY 298

Query: 122 VPYFKDKGDSNSSAGWK 138
           VPYFKDKGDSNSSAGWK
Sbjct: 299 VPYFKDKGDSNSSAGWK 315



 Score =  114 bits (285), Expect = 3e-25
 Identities = 83/180 (46%), Positives = 90/180 (50%), Gaps = 30/180 (16%)

Query: 430 PPAPRPGPVLGAPGELALAGAAAA-------------YPGKGAAPYAPPAPSRSALAHPI 476
           P AP PGPV  A    A   + A+              P  G A       +  ALA P 
Sbjct: 393 PSAPAPGPVPAAAKWAASPASHASDDYEAWADFRGGGRPLLGEAAELEDDEALEALA-PS 451

Query: 477 SLMTLPGEAGAA----GLAPPGHA---AAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDR 529
           S +  P  A A     G   PG     A  GGP G        G  A    G L  A D 
Sbjct: 452 SPLMYPSPASALSPALGSRCPGELPRLAELGGPLG-----LHGGGGAGLPEGLLDGAQDA 506

Query: 530 FPADLDLDMFSGSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPPNQSWVPG 589
           +         +G+LECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPPNQSWVPG
Sbjct: 507 YGPRAR----AGTLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPPNQSWVPG 562


>gi|103472003 forkhead box O4 [Homo sapiens]
          Length = 505

 Score =  190 bits (482), Expect = 4e-48
 Identities = 185/588 (31%), Positives = 253/588 (43%), Gaps = 132/588 (22%)

Query: 10  VDVDPDFAPQSRPRSCTWPLPQPDLAGD--EDGALGAGVAEGAEDCGPERRATAPAMAPA 67
           +D+DPDF PQSRPRSCTWPLP+P++A    E   +   + E     G       P+  P 
Sbjct: 16  IDLDPDFEPQSRPRSCTWPLPRPEIANQPSEPPEVEPDLGEKVHTEGRSEPILLPSRLPE 75

Query: 68  PP-------LGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVR 120
           P        LGA  GP  +   SRRNAWGN SYA+LI++AIESAP+KRLTL+QIY+WMVR
Sbjct: 76  PAGGPQPGILGAVTGP--RKGGSRRNAWGNQSYAELISQAIESAPEKRLTLAQIYEWMVR 133

Query: 121 YVPYFKDKGDSNSSAGWKVGASGWGGGWGRRLGLPGAARCVGLQE---GRQKEGFLAPPG 177
            VPYFKDKGDSNSSAGWK            R  L   ++ + +     G+     L P G
Sbjct: 134 TVPYFKDKGDSNSSAGWKNSI---------RHNLSLHSKFIKVHNEATGKSSWWMLNPEG 184

Query: 178 VTESCSSRAP--------SSSFVLRG-SPAPRADGGGEVTFPEVATCEVVDLGIGPQARA 228
                S +AP        SSS +LRG S AP+         P V       L   P+   
Sbjct: 185 ---GKSGKAPRRRAASMDSSSKLLRGRSKAPKKK-------PSV-------LPAPPEGAT 227

Query: 229 FSVPLGASLQGWGTAAGPSPELGSGQGWLPFYPFSTADPSAEDLHMASGPWHHPGHIFCQ 288
            + P+G   +  G+    + E      W  F P S+++ S+    ++         +  +
Sbjct: 228 PTSPVGHFAKWSGSPCSRNRE--EADMWTTFRPRSSSNASSVSTRLSP--------LRPE 277

Query: 289 EEAWTENLNFTPDGRANGLPRALNQGLQRTRQGKAGKSQLLPSKARKCQRQGAWGPEESD 348
            E   E +  +    A G+P  LN+GL+         S  L S                 
Sbjct: 278 SEVLAEEIPASVSSYAGGVPPTLNEGLELLDGLNLTSSHSLLS----------------- 320

Query: 349 QCLELGQYLDQEVEATRTGLAKAG-SDMGSTGDWHSRIKKRMYGEMAEVFWRVNGDFATH 407
                           R+GL+       G TG  H+          + +F    G  +  
Sbjct: 321 ----------------RSGLSGFSLQHPGVTGPLHT--------YSSSLFSPAEGPLSAG 356

Query: 408 CGDFEKAPTARGLEGRQVVPPPPPA----PRPGPVLG-APGELALAG---AAAAYPGKGA 459
            G F  +     L       PPPPA     +  P+L  AP  L L G   ++    G G 
Sbjct: 357 EGCFSSSQALEALLTSDT--PPPPADVLMTQVDPILSQAPTLLLLGGLPSSSKLATGVGL 414

Query: 460 APYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAA 519
            P    AP  S+L   +S++  P    +A +            P  L    L  P  A  
Sbjct: 415 CPKPLEAPGPSSLVPTLSMIAPPPVMASAPI------------PKALGTPVLTPPTEA-- 460

Query: 520 AGPLGAAPDRFPADLDLDMFSGSLECDVESIILNDFMDSDE-MDFNFD 566
                A+ DR P DLDLDM+  +LECD+++II +D MD  E +DFNF+
Sbjct: 461 -----ASQDRMPQDLDLDMYMENLECDMDNII-SDLMDEGEGLDFNFE 502


>gi|42519916 forkhead box O3A [Homo sapiens]
          Length = 673

 Score =  145 bits (365), Expect = 1e-34
 Identities = 91/199 (45%), Positives = 106/199 (53%), Gaps = 63/199 (31%)

Query: 3   AKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAG-----------------------DED 39
           A L   +V++DP+F PQSRPRSCTWPL +P+L                         DED
Sbjct: 9   APLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEEEDDEDDED 68

Query: 40  G--------ALGAG------------------VAEGAEDCGPERRATAPAMA-------- 65
           G        A+G G                  +A G +D G      A  ++        
Sbjct: 69  GGGRAGSAMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLSGGTQALLQ 128

Query: 66  -----PAPPLGAEVGPLRKAK-SSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMV 119
                P P  GA  G  +  K SSRRNAWGNLSYADLIT+AIES+PDKRLTLSQIY+WMV
Sbjct: 129 PQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMV 188

Query: 120 RYVPYFKDKGDSNSSAGWK 138
           R VPYFKDKGDSNSSAGWK
Sbjct: 189 RCVPYFKDKGDSNSSAGWK 207



 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 43/92 (46%), Positives = 58/92 (63%), Gaps = 10/92 (10%)

Query: 507 LLDALPGP--YAAAAAGPLGAAPDRFPADLDLDMFSGSLECDVESIILNDFMDSDEMDFN 564
           L D+L G   Y+ +A  P+    ++FP+DLDLDMF+GSLECD+ESII ++ MD+D +DFN
Sbjct: 583 LSDSLSGSSLYSTSANLPV-MGHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFN 641

Query: 565 FDSALPPP------PPGLAGA-PPPNQSWVPG 589
           FDS +              GA    +QSWVPG
Sbjct: 642 FDSLISTQNVVGLNVGNFTGAKQASSQSWVPG 673


>gi|4503739 forkhead box O3A [Homo sapiens]
          Length = 673

 Score =  145 bits (365), Expect = 1e-34
 Identities = 91/199 (45%), Positives = 106/199 (53%), Gaps = 63/199 (31%)

Query: 3   AKLRAHQVDVDPDFAPQSRPRSCTWPLPQPDLAG-----------------------DED 39
           A L   +V++DP+F PQSRPRSCTWPL +P+L                         DED
Sbjct: 9   APLSPLEVELDPEFEPQSRPRSCTWPLQRPELQASPAKPSGETAADSMIPEEEDDEDDED 68

Query: 40  G--------ALGAG------------------VAEGAEDCGPERRATAPAMA-------- 65
           G        A+G G                  +A G +D G      A  ++        
Sbjct: 69  GGGRAGSAMAIGGGGGSGTLGSGLLLEDSARVLAPGGQDPGSGPATAAGGLSGGTQALLQ 128

Query: 66  -----PAPPLGAEVGPLRKAK-SSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMV 119
                P P  GA  G  +  K SSRRNAWGNLSYADLIT+AIES+PDKRLTLSQIY+WMV
Sbjct: 129 PQQPLPPPQPGAAGGSGQPRKCSSRRNAWGNLSYADLITRAIESSPDKRLTLSQIYEWMV 188

Query: 120 RYVPYFKDKGDSNSSAGWK 138
           R VPYFKDKGDSNSSAGWK
Sbjct: 189 RCVPYFKDKGDSNSSAGWK 207



 Score = 72.0 bits (175), Expect = 1e-12
 Identities = 43/92 (46%), Positives = 58/92 (63%), Gaps = 10/92 (10%)

Query: 507 LLDALPGP--YAAAAAGPLGAAPDRFPADLDLDMFSGSLECDVESIILNDFMDSDEMDFN 564
           L D+L G   Y+ +A  P+    ++FP+DLDLDMF+GSLECD+ESII ++ MD+D +DFN
Sbjct: 583 LSDSLSGSSLYSTSANLPV-MGHEKFPSDLDLDMFNGSLECDMESIIRSELMDADGLDFN 641

Query: 565 FDSALPPP------PPGLAGA-PPPNQSWVPG 589
           FDS +              GA    +QSWVPG
Sbjct: 642 FDSLISTQNVVGLNVGNFTGAKQASSQSWVPG 673


>gi|9257222 forkhead box O1 [Homo sapiens]
          Length = 655

 Score =  141 bits (355), Expect = 2e-33
 Identities = 88/203 (43%), Positives = 100/203 (49%), Gaps = 74/203 (36%)

Query: 10  VDVDPDFAPQSRPRSCTWPLPQPDL----------------AGDEDGALGAGVAEGA--- 50
           V++DPDF P  RPRSCTWPLP+P+                 A + D A G   A  A   
Sbjct: 8   VEIDPDFEPLPRPRSCTWPLPRPEFSQSNSATSSPAPSGSAAANPDAAAGLPSASAAAVS 67

Query: 51  -------------ED------------------------CGPERRATAPAMAPAPPLGAE 73
                        ED                        CG  +   A  + PAPP    
Sbjct: 68  ADFMSNLSLLEESEDFPQAPGSVAAAVAAAAAAAATGGLCGDFQGPEAGCLHPAPPQPPP 127

Query: 74  VGPL------------------RKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIY 115
            GPL                  RK+ SSRRNAWGNLSYADLITKAIES+ +KRLTLSQIY
Sbjct: 128 PGPLSQHPPVPPAAAGPLAGQPRKSSSSRRNAWGNLSYADLITKAIESSAEKRLTLSQIY 187

Query: 116 DWMVRYVPYFKDKGDSNSSAGWK 138
           +WMV+ VPYFKDKGDSNSSAGWK
Sbjct: 188 EWMVKSVPYFKDKGDSNSSAGWK 210



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 25/43 (58%), Positives = 32/43 (74%), Gaps = 1/43 (2%)

Query: 528 DRFPADLDLDMFSGSLECDVESIILNDFMDSDEMDFNFDSALP 570
           ++ P+DLD  MF   L+CD+ESII ND MD D +DFNFD+ LP
Sbjct: 596 EKLPSDLD-GMFIERLDCDMESIIRNDLMDGDTLDFNFDNVLP 637



 Score = 33.1 bits (74), Expect = 0.73
 Identities = 43/143 (30%), Positives = 48/143 (33%), Gaps = 31/143 (21%)

Query: 410 DFEKAPTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAA-PYAPPAPS 468
           DFE  P  R          P P P       A    A +G+AAA P   A  P A  A  
Sbjct: 13  DFEPLPRPRSCTW------PLPRPEFSQSNSATSSPAPSGSAAANPDAAAGLPSASAAAV 66

Query: 469 RSALAHPISLMT-------LPGE------AGAAGLAPPGHAAAFGGPPGGLLLDALP--- 512
            +     +SL+         PG       A AA  A  G    F GP  G L  A P   
Sbjct: 67  SADFMSNLSLLEESEDFPQAPGSVAAAVAAAAAAAATGGLCGDFQGPEAGCLHPAPPQPP 126

Query: 513 --------GPYAAAAAGPLGAAP 527
                    P   AAAGPL   P
Sbjct: 127 PPGPLSQHPPVPPAAAGPLAGQP 149


>gi|24497501 forkhead box A1 [Homo sapiens]
          Length = 472

 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 35/95 (36%), Positives = 46/95 (48%), Gaps = 8/95 (8%)

Query: 40  GALGAGVAEGAEDCGPERRATAPAMAPAPPLGAEVGPLRKA--------KSSRRNAWGNL 91
           GA+GA  A      GP   A  P M+P     + +G  R          K S  +A    
Sbjct: 114 GAMGAQQAASMNGLGPYAAAMNPCMSPMAYAPSNLGRSRAGGGGDAKTFKRSYPHAKPPY 173

Query: 92  SYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFK 126
           SY  LIT AI+ AP K LTLS+IY W++   PY++
Sbjct: 174 SYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYR 208


>gi|195947376 forkhead box I2 [Homo sapiens]
          Length = 318

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 49/150 (32%), Positives = 68/150 (45%), Gaps = 31/150 (20%)

Query: 11  DVDPDFAPQSRPRSCTWPLPQPDLAGDEDGALGAG--VAEGAEDCGPERRATAPAMAP-- 66
           D+ P  AP  + ++   P   P     + GA+G G  +   A    P+  A+ P  AP  
Sbjct: 7   DLGPSSAPPGQAQATAHP---PGYEPGDLGAVGGGPLLWVNAPALSPKSYASGPGPAPPY 63

Query: 67  -APPLGAEVGPLRKAKSSRRNA---WGNLS--------------YADLITKAIESAPDKR 108
            AP  GA  GPL  A      A   W +LS              Y+ LI  AI+SAP ++
Sbjct: 64  AAPSYGAP-GPLLGAPGGLAGADLAWLSLSGQQELLRLVRPPYSYSALIAMAIQSAPLRK 122

Query: 109 LTLSQIYDWMVRYVPYFKDKGDSNSSAGWK 138
           LTLSQIY ++    P++K      S AGW+
Sbjct: 123 LTLSQIYQYVAGNFPFYK-----RSKAGWQ 147


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein
           [Homo sapiens]
          Length = 1650

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 43/118 (36%), Positives = 49/118 (41%), Gaps = 25/118 (21%)

Query: 415 PTARGLEGRQVVPPPPPAP---RPGPVLGAPGELALAGAAAAYPGKG-AAPYAPPAPSRS 470
           P   G EG +  P PP AP    P  + G PGE  L G A     KG   P  PP P+ S
Sbjct: 871 PGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGS 930

Query: 471 ALAHPISLMTLPGEAGAAG----LAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLG 524
                      PGE GAAG    + PPG      GPPG      +PG       GP+G
Sbjct: 931 -----------PGERGAAGSGGPIGPPGRPGP-QGPPGAAGEKGVPG-----EKGPIG 971



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 42/127 (33%), Positives = 50/127 (39%), Gaps = 24/127 (18%)

Query: 415  PTAR-GLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALA 473
            PT R G++G   +P P   P      G  GE+   G       KG   + PP P      
Sbjct: 972  PTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGE--HGPPGPPG---- 1025

Query: 474  HPISLMTLPGEAGAAG----LAPPGHAAA--------FGGPPGGLLLDALPGPYA----A 517
             PI  +  PG AGA G      P GH  A        F GPPG + L  LPGP       
Sbjct: 1026 -PIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGET 1084

Query: 518  AAAGPLG 524
               GP+G
Sbjct: 1085 GDVGPMG 1091



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 38/94 (40%), Positives = 41/94 (43%), Gaps = 12/94 (12%)

Query: 435 PGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEAGAAGLA-PP 493
           PGP  G PGE  L G A     KG  P  P AP +     P  L   PGE G  G A  P
Sbjct: 859 PGPP-GPPGEQGLPGTAGKEGTKGD-PGPPGAPGKDG---PAGLRGFPGERGLPGTAGGP 913

Query: 494 GHAAAFG--GPPGGLLLDALPGPY-AAAAAGPLG 524
           G     G  GPPG       PG   AA + GP+G
Sbjct: 914 GLKGNEGPSGPPGPA---GSPGERGAAGSGGPIG 944



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 46/143 (32%), Positives = 55/143 (38%), Gaps = 43/143 (30%)

Query: 415  PTARGLEGRQ-VVPPPPPAPRPGP--VLGAPGELALAGAAAAYPGKGA-APYAPP----- 465
            P A G  G+   V P  PA +PGP  + G PG +   G   A    G   P  PP     
Sbjct: 1255 PGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGL 1314

Query: 466  ---APSRSALAHP--ISLMTLPGEAGAAG----------------LAPPGHAAAF--GGP 502
               A ++    HP  I L+  PGE G  G                +  PG +     GGP
Sbjct: 1315 RGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGP 1374

Query: 503  PGGLLLDALPGPYAAAAAGPLGA 525
            PG      LPGP     AGP GA
Sbjct: 1375 PG------LPGP-----AGPKGA 1386



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 39/118 (33%), Positives = 45/118 (38%), Gaps = 14/118 (11%)

Query: 417  ARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAA------YPGKGAA--PYAPPAPS 468
            A+G  G    P  P +P P    G PG L   G A +        GKGA   P A  AP 
Sbjct: 1203 AKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPG 1262

Query: 469  RSALAHPISLMTLPGEAGAAGL----APPGHAAAFG--GPPGGLLLDALPGPYAAAAA 520
            ++    P      PG  G  GL       G   A G  GPPG +    LPG    A A
Sbjct: 1263 KTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGA 1320



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 35/112 (31%), Positives = 41/112 (36%), Gaps = 20/112 (17%)

Query: 415  PTARGLEGRQVVPPPPPAPRP-GPV-----LGAPGELALAGAAAAYPGKGA-------AP 461
            P  +G +G +    PP  P P GPV      GA GE    G    +  KG         P
Sbjct: 1006 PGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGP 1065

Query: 462  YAP------PAPS-RSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGL 506
              P      P PS        +  M  PG  G  G A P  A    GPPGG+
Sbjct: 1066 PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGV 1117



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 27/85 (31%), Positives = 30/85 (35%), Gaps = 6/85 (7%)

Query: 440 GAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAF 499
           G PGE    G   A       P  P           I    LPGE+G  GL  P      
Sbjct: 479 GLPGEKGHRGDTGAQ----GLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGI 534

Query: 500 GGPPGGLLLDALPGPYAAAAAGPLG 524
            GPPG   +D   GP    + GP G
Sbjct: 535 PGPPGVRGMDGPQGP--KGSLGPQG 557



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 35/105 (33%), Positives = 37/105 (35%), Gaps = 23/105 (21%)

Query: 430 PPAP-----RPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGE 484
           PP P     RPGP LG PG   L G +         P  P  P          L   PG+
Sbjct: 402 PPGPMGYTGRPGP-LGQPGSPGLKGESG-----DLGPQGPRGPQ--------GLTGPPGK 447

Query: 485 AGAAGLAPPGHAAAFGGPP---GGLLLDALPG-PYAAAAAGPLGA 525
           AG  G A    A    G P   G    D LPG P      G  GA
Sbjct: 448 AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGA 492



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 35/137 (25%), Positives = 46/137 (33%), Gaps = 22/137 (16%)

Query: 420 LEGRQVVPPPPPAPRPGPVLGAPGELALAGAAA-----AYPGKGAAPYA--PPAPSRSAL 472
           LE   +V  PP    P  ++G PG     G          PG+   P +   P P  ++L
Sbjct: 305 LEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSL 364

Query: 473 AHPISLMTLPGEAGAAGLAPPGHA--------AAFGGPPGGLLLDALPGPYA-------A 517
             P    +  G+ G    A    A         A  GPPG +     PGP          
Sbjct: 365 MLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLK 424

Query: 518 AAAGPLGAAPDRFPADL 534
             +G LG    R P  L
Sbjct: 425 GESGDLGPQGPRGPQGL 441



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 41/129 (31%), Positives = 47/129 (36%), Gaps = 27/129 (20%)

Query: 415 PTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPG-KGAAPY----APPAPSR 469
           P  RGL G Q  P   P P+  P  G PG+  L G    +PG +G   +     PP P  
Sbjct: 787 PGERGLPGPQG-PNGFPGPKGPP--GPPGKDGLPG----HPGQRGEVGFQGKTGPPGPPG 839

Query: 470 SALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAA----GPLGA 525
                      + G  GAAG   P       GPPG      LPG           GP GA
Sbjct: 840 -----------VVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGA 888

Query: 526 APDRFPADL 534
                PA L
Sbjct: 889 PGKDGPAGL 897



 Score = 30.8 bits (68), Expect = 3.6
 Identities = 22/65 (33%), Positives = 26/65 (40%), Gaps = 1/65 (1%)

Query: 140 GASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRAPSSSFVLRGSPAP 199
           G  G  G  G R GLPG +   GL   +   G   PPGV      + P  S   +G P P
Sbjct: 503 GERGDDGEIGPR-GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP 561

Query: 200 RADGG 204
               G
Sbjct: 562 PGQQG 566



 Score = 30.0 bits (66), Expect = 6.2
 Identities = 38/135 (28%), Positives = 43/135 (31%), Gaps = 43/135 (31%)

Query: 417 ARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAA----PYAPPAPSRSAL 472
           ARGL G+       P    GP  G  G+    GA      KG +    P+ PP       
Sbjct: 741 ARGLSGKS-----GPRGERGPT-GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG--- 791

Query: 473 AHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPG----------------PYA 516
                   LPG  G  G   P       GPPG    D LPG                P  
Sbjct: 792 --------LPGPQGPNGFPGPK------GPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP 837

Query: 517 AAAAGPLGAAPDRFP 531
               GP GAA +  P
Sbjct: 838 PGVVGPQGAAGETGP 852


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein
           [Homo sapiens]
          Length = 1629

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 43/118 (36%), Positives = 49/118 (41%), Gaps = 25/118 (21%)

Query: 415 PTARGLEGRQVVPPPPPAP---RPGPVLGAPGELALAGAAAAYPGKG-AAPYAPPAPSRS 470
           P   G EG +  P PP AP    P  + G PGE  L G A     KG   P  PP P+ S
Sbjct: 850 PGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGS 909

Query: 471 ALAHPISLMTLPGEAGAAG----LAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLG 524
                      PGE GAAG    + PPG      GPPG      +PG       GP+G
Sbjct: 910 -----------PGERGAAGSGGPIGPPGRPGP-QGPPGAAGEKGVPG-----EKGPIG 950



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 42/127 (33%), Positives = 50/127 (39%), Gaps = 24/127 (18%)

Query: 415  PTAR-GLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALA 473
            PT R G++G   +P P   P      G  GE+   G       KG   + PP P      
Sbjct: 951  PTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGE--HGPPGPPG---- 1004

Query: 474  HPISLMTLPGEAGAAG----LAPPGHAAA--------FGGPPGGLLLDALPGPYA----A 517
             PI  +  PG AGA G      P GH  A        F GPPG + L  LPGP       
Sbjct: 1005 -PIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGET 1063

Query: 518  AAAGPLG 524
               GP+G
Sbjct: 1064 GDVGPMG 1070



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 38/94 (40%), Positives = 41/94 (43%), Gaps = 12/94 (12%)

Query: 435 PGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEAGAAGLA-PP 493
           PGP  G PGE  L G A     KG  P  P AP +     P  L   PGE G  G A  P
Sbjct: 838 PGPP-GPPGEQGLPGTAGKEGTKGD-PGPPGAPGKDG---PAGLRGFPGERGLPGTAGGP 892

Query: 494 GHAAAFG--GPPGGLLLDALPGPY-AAAAAGPLG 524
           G     G  GPPG       PG   AA + GP+G
Sbjct: 893 GLKGNEGPSGPPGPA---GSPGERGAAGSGGPIG 923



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 46/143 (32%), Positives = 55/143 (38%), Gaps = 43/143 (30%)

Query: 415  PTARGLEGRQ-VVPPPPPAPRPGP--VLGAPGELALAGAAAAYPGKGA-APYAPP----- 465
            P A G  G+   V P  PA +PGP  + G PG +   G   A    G   P  PP     
Sbjct: 1234 PGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGL 1293

Query: 466  ---APSRSALAHP--ISLMTLPGEAGAAG----------------LAPPGHAAAF--GGP 502
               A ++    HP  I L+  PGE G  G                +  PG +     GGP
Sbjct: 1294 RGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGP 1353

Query: 503  PGGLLLDALPGPYAAAAAGPLGA 525
            PG      LPGP     AGP GA
Sbjct: 1354 PG------LPGP-----AGPKGA 1365



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 39/118 (33%), Positives = 45/118 (38%), Gaps = 14/118 (11%)

Query: 417  ARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAA------YPGKGAA--PYAPPAPS 468
            A+G  G    P  P +P P    G PG L   G A +        GKGA   P A  AP 
Sbjct: 1182 AKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPG 1241

Query: 469  RSALAHPISLMTLPGEAGAAGL----APPGHAAAFG--GPPGGLLLDALPGPYAAAAA 520
            ++    P      PG  G  GL       G   A G  GPPG +    LPG    A A
Sbjct: 1242 KTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGA 1299



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 35/112 (31%), Positives = 41/112 (36%), Gaps = 20/112 (17%)

Query: 415  PTARGLEGRQVVPPPPPAPRP-GPV-----LGAPGELALAGAAAAYPGKGA-------AP 461
            P  +G +G +    PP  P P GPV      GA GE    G    +  KG         P
Sbjct: 985  PGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGP 1044

Query: 462  YAP------PAPS-RSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGL 506
              P      P PS        +  M  PG  G  G A P  A    GPPGG+
Sbjct: 1045 PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGV 1096



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 27/85 (31%), Positives = 30/85 (35%), Gaps = 6/85 (7%)

Query: 440 GAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAF 499
           G PGE    G   A       P  P           I    LPGE+G  GL  P      
Sbjct: 458 GLPGEKGHRGDTGAQ----GLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGI 513

Query: 500 GGPPGGLLLDALPGPYAAAAAGPLG 524
            GPPG   +D   GP    + GP G
Sbjct: 514 PGPPGVRGMDGPQGP--KGSLGPQG 536



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 35/105 (33%), Positives = 37/105 (35%), Gaps = 23/105 (21%)

Query: 430 PPAP-----RPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGE 484
           PP P     RPGP LG PG   L G +         P  P  P          L   PG+
Sbjct: 381 PPGPMGYTGRPGP-LGQPGSPGLKGESG-----DLGPQGPRGPQ--------GLTGPPGK 426

Query: 485 AGAAGLAPPGHAAAFGGPP---GGLLLDALPG-PYAAAAAGPLGA 525
           AG  G A    A    G P   G    D LPG P      G  GA
Sbjct: 427 AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGA 471



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 35/137 (25%), Positives = 46/137 (33%), Gaps = 22/137 (16%)

Query: 420 LEGRQVVPPPPPAPRPGPVLGAPGELALAGAAA-----AYPGKGAAPYA--PPAPSRSAL 472
           LE   +V  PP    P  ++G PG     G          PG+   P +   P P  ++L
Sbjct: 284 LEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSL 343

Query: 473 AHPISLMTLPGEAGAAGLAPPGHA--------AAFGGPPGGLLLDALPGPYA-------A 517
             P    +  G+ G    A    A         A  GPPG +     PGP          
Sbjct: 344 MLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLK 403

Query: 518 AAAGPLGAAPDRFPADL 534
             +G LG    R P  L
Sbjct: 404 GESGDLGPQGPRGPQGL 420



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 41/129 (31%), Positives = 47/129 (36%), Gaps = 27/129 (20%)

Query: 415 PTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPG-KGAAPY----APPAPSR 469
           P  RGL G Q  P   P P+  P  G PG+  L G    +PG +G   +     PP P  
Sbjct: 766 PGERGLPGPQG-PNGFPGPKGPP--GPPGKDGLPG----HPGQRGEVGFQGKTGPPGPPG 818

Query: 470 SALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAA----GPLGA 525
                      + G  GAAG   P       GPPG      LPG           GP GA
Sbjct: 819 -----------VVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGA 867

Query: 526 APDRFPADL 534
                PA L
Sbjct: 868 PGKDGPAGL 876



 Score = 30.8 bits (68), Expect = 3.6
 Identities = 22/65 (33%), Positives = 26/65 (40%), Gaps = 1/65 (1%)

Query: 140 GASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRAPSSSFVLRGSPAP 199
           G  G  G  G R GLPG +   GL   +   G   PPGV      + P  S   +G P P
Sbjct: 482 GERGDDGEIGPR-GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP 540

Query: 200 RADGG 204
               G
Sbjct: 541 PGQQG 545



 Score = 30.0 bits (66), Expect = 6.2
 Identities = 38/135 (28%), Positives = 43/135 (31%), Gaps = 43/135 (31%)

Query: 417 ARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAA----PYAPPAPSRSAL 472
           ARGL G+       P    GP  G  G+    GA      KG +    P+ PP       
Sbjct: 720 ARGLSGKS-----GPRGERGPT-GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG--- 770

Query: 473 AHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPG----------------PYA 516
                   LPG  G  G   P       GPPG    D LPG                P  
Sbjct: 771 --------LPGPQGPNGFPGPK------GPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP 816

Query: 517 AAAAGPLGAAPDRFP 531
               GP GAA +  P
Sbjct: 817 PGVVGPQGAAGETGP 831


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 43/118 (36%), Positives = 49/118 (41%), Gaps = 25/118 (21%)

Query: 415  PTARGLEGRQVVPPPPPAP---RPGPVLGAPGELALAGAAAAYPGKG-AAPYAPPAPSRS 470
            P   G EG +  P PP AP    P  + G PGE  L G A     KG   P  PP P+ S
Sbjct: 957  PGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGS 1016

Query: 471  ALAHPISLMTLPGEAGAAG----LAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLG 524
                       PGE GAAG    + PPG      GPPG      +PG       GP+G
Sbjct: 1017 -----------PGERGAAGSGGPIGPPGRPGP-QGPPGAAGEKGVPG-----EKGPIG 1057



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 42/127 (33%), Positives = 50/127 (39%), Gaps = 24/127 (18%)

Query: 415  PTAR-GLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALA 473
            PT R G++G   +P P   P      G  GE+   G       KG   + PP P      
Sbjct: 1058 PTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGE--HGPPGPPG---- 1111

Query: 474  HPISLMTLPGEAGAAG----LAPPGHAAA--------FGGPPGGLLLDALPGPYA----A 517
             PI  +  PG AGA G      P GH  A        F GPPG + L  LPGP       
Sbjct: 1112 -PIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGET 1170

Query: 518  AAAGPLG 524
               GP+G
Sbjct: 1171 GDVGPMG 1177



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 38/94 (40%), Positives = 41/94 (43%), Gaps = 12/94 (12%)

Query: 435  PGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEAGAAGLA-PP 493
            PGP  G PGE  L G A     KG  P  P AP +     P  L   PGE G  G A  P
Sbjct: 945  PGPP-GPPGEQGLPGTAGKEGTKGD-PGPPGAPGKDG---PAGLRGFPGERGLPGTAGGP 999

Query: 494  GHAAAFG--GPPGGLLLDALPGPY-AAAAAGPLG 524
            G     G  GPPG       PG   AA + GP+G
Sbjct: 1000 GLKGNEGPSGPPGPA---GSPGERGAAGSGGPIG 1030



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 46/143 (32%), Positives = 55/143 (38%), Gaps = 43/143 (30%)

Query: 415  PTARGLEGRQ-VVPPPPPAPRPGP--VLGAPGELALAGAAAAYPGKGA-APYAPP----- 465
            P A G  G+   V P  PA +PGP  + G PG +   G   A    G   P  PP     
Sbjct: 1341 PGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGL 1400

Query: 466  ---APSRSALAHP--ISLMTLPGEAGAAG----------------LAPPGHAAAF--GGP 502
               A ++    HP  I L+  PGE G  G                +  PG +     GGP
Sbjct: 1401 RGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGP 1460

Query: 503  PGGLLLDALPGPYAAAAAGPLGA 525
            PG      LPGP     AGP GA
Sbjct: 1461 PG------LPGP-----AGPKGA 1472



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 39/118 (33%), Positives = 45/118 (38%), Gaps = 14/118 (11%)

Query: 417  ARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAA------YPGKGAA--PYAPPAPS 468
            A+G  G    P  P +P P    G PG L   G A +        GKGA   P A  AP 
Sbjct: 1289 AKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPG 1348

Query: 469  RSALAHPISLMTLPGEAGAAGL----APPGHAAAFG--GPPGGLLLDALPGPYAAAAA 520
            ++    P      PG  G  GL       G   A G  GPPG +    LPG    A A
Sbjct: 1349 KTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGA 1406



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 35/112 (31%), Positives = 41/112 (36%), Gaps = 20/112 (17%)

Query: 415  PTARGLEGRQVVPPPPPAPRP-GPV-----LGAPGELALAGAAAAYPGKGA-------AP 461
            P  +G +G +    PP  P P GPV      GA GE    G    +  KG         P
Sbjct: 1092 PGQKGTKGNKGEHGPPGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGP 1151

Query: 462  YAP------PAPS-RSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGL 506
              P      P PS        +  M  PG  G  G A P  A    GPPGG+
Sbjct: 1152 PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGV 1203



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 27/85 (31%), Positives = 30/85 (35%), Gaps = 6/85 (7%)

Query: 440 GAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAF 499
           G PGE    G   A       P  P           I    LPGE+G  GL  P      
Sbjct: 565 GLPGEKGHRGDTGAQ----GLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGI 620

Query: 500 GGPPGGLLLDALPGPYAAAAAGPLG 524
            GPPG   +D   GP    + GP G
Sbjct: 621 PGPPGVRGMDGPQGP--KGSLGPQG 643



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 35/105 (33%), Positives = 37/105 (35%), Gaps = 23/105 (21%)

Query: 430 PPAP-----RPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGE 484
           PP P     RPGP LG PG   L G +         P  P  P          L   PG+
Sbjct: 488 PPGPMGYTGRPGP-LGQPGSPGLKGESG-----DLGPQGPRGPQ--------GLTGPPGK 533

Query: 485 AGAAGLAPPGHAAAFGGPP---GGLLLDALPG-PYAAAAAGPLGA 525
           AG  G A    A    G P   G    D LPG P      G  GA
Sbjct: 534 AGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGA 578



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 35/137 (25%), Positives = 46/137 (33%), Gaps = 22/137 (16%)

Query: 420 LEGRQVVPPPPPAPRPGPVLGAPGELALAGAAA-----AYPGKGAAPYA--PPAPSRSAL 472
           LE   +V  PP    P  ++G PG     G          PG+   P +   P P  ++L
Sbjct: 391 LEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSL 450

Query: 473 AHPISLMTLPGEAGAAGLAPPGHA--------AAFGGPPGGLLLDALPGPYA-------A 517
             P    +  G+ G    A    A         A  GPPG +     PGP          
Sbjct: 451 MLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGRPGPLGQPGSPGLK 510

Query: 518 AAAGPLGAAPDRFPADL 534
             +G LG    R P  L
Sbjct: 511 GESGDLGPQGPRGPQGL 527



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 41/129 (31%), Positives = 47/129 (36%), Gaps = 27/129 (20%)

Query: 415 PTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPG-KGAAPY----APPAPSR 469
           P  RGL G Q  P   P P+  P  G PG+  L G    +PG +G   +     PP P  
Sbjct: 873 PGERGLPGPQG-PNGFPGPKGPP--GPPGKDGLPG----HPGQRGEVGFQGKTGPPGPPG 925

Query: 470 SALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAA----GPLGA 525
                      + G  GAAG   P       GPPG      LPG           GP GA
Sbjct: 926 -----------VVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGA 974

Query: 526 APDRFPADL 534
                PA L
Sbjct: 975 PGKDGPAGL 983



 Score = 30.8 bits (68), Expect = 3.6
 Identities = 22/65 (33%), Positives = 26/65 (40%), Gaps = 1/65 (1%)

Query: 140 GASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRAPSSSFVLRGSPAP 199
           G  G  G  G R GLPG +   GL   +   G   PPGV      + P  S   +G P P
Sbjct: 589 GERGDDGEIGPR-GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGP 647

Query: 200 RADGG 204
               G
Sbjct: 648 PGQQG 652



 Score = 30.0 bits (66), Expect = 6.2
 Identities = 38/135 (28%), Positives = 43/135 (31%), Gaps = 43/135 (31%)

Query: 417 ARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAA----PYAPPAPSRSAL 472
           ARGL G+       P    GP  G  G+    GA      KG +    P+ PP       
Sbjct: 827 ARGLSGKS-----GPRGERGPT-GPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG--- 877

Query: 473 AHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPG----------------PYA 516
                   LPG  G  G   P       GPPG    D LPG                P  
Sbjct: 878 --------LPGPQGPNGFPGPK------GPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGP 923

Query: 517 AAAAGPLGAAPDRFP 531
               GP GAA +  P
Sbjct: 924 PGVVGPQGAAGETGP 938


>gi|22779860 forkhead box L1 [Homo sapiens]
          Length = 345

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 62/245 (25%), Positives = 95/245 (38%), Gaps = 37/245 (15%)

Query: 54  GPERRATAPAMAPAPPLGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQ 113
           GPER     A APA  L A      +A++ ++  +   SY  LI  AI+ AP++R+TL+ 
Sbjct: 22  GPERPGLPLAFAPAAALAAS----GRAETPQKPPY---SYIALIAMAIQDAPEQRVTLNG 74

Query: 114 IYDWMVRYVPYFKDKGDS-NSSAGWKVGASGWGGGWGRRLGLPGAA-------RCVGLQE 165
           IY +++   P++ D      +S    +  +       R  G PG         RC+ + E
Sbjct: 75  IYQFIMDRFPFYHDNRQGWQNSIRHNLSLNDCFVKVPREKGRPGKGSYWTLDPRCLDMFE 134

Query: 166 G----RQKEGFLAPPGVTESCSSRAPSSSFVLRGSPAPRADGGGEVTFPEVATCEVVDLG 221
                R+K      PG  E+   RA +        P   +  GG  + P ++  +    G
Sbjct: 135 NGNYRRRKRKPKPGPGAPEAKRPRAETHQRSAEAQPEAGSGAGG--SGPAISRLQAAPAG 192

Query: 222 IGPQARAFSVP--------------LGASLQG-WGTAAGPSPELGSGQGWLPFYPFSTAD 266
             P     S P               G + QG    A G +   G G G  P  P S + 
Sbjct: 193 PSPLLDGPSPPAPLHWPGTASPNEDAGDAAQGAAAVAVGQAARTGDGPG-SPLRPASRSS 251

Query: 267 PSAED 271
           P + D
Sbjct: 252 PKSSD 256



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 37/126 (29%), Positives = 46/126 (36%), Gaps = 26/126 (20%)

Query: 428 PPPPAPRPGPVLGAP----GELALAGAAAAY---------PGKGAAPYAPPAPSRSALAH 474
           P PPAP   P   +P    G+ A   AA A          PG    P +  +P  S  + 
Sbjct: 200 PSPPAPLHWPGTASPNEDAGDAAQGAAAVAVGQAARTGDGPGSPLRPASRSSPKSSDKSK 259

Query: 475 PISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPD---RFP 531
             S+ ++   AG  G  PP      GG        A PGP     A  L A+      F 
Sbjct: 260 SFSIDSI--LAGKQGQKPPSGDELLGG--------AKPGPGGRLGASLLAASSSLRPPFN 309

Query: 532 ADLDLD 537
           A L LD
Sbjct: 310 ASLMLD 315


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 43/108 (39%), Positives = 49/108 (45%), Gaps = 14/108 (12%)

Query: 425 VVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGE 484
           ++P P PA  PG V+  P      GAAA       AP AP  P+  A A P +    P  
Sbjct: 225 LLPLPKPA-APGTVIQTP---PFVGAAAP-----PAPAAPSPPAAPAPAAPAAAPPPPPP 275

Query: 485 AGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRFPA 532
           A A    PPGH A   GPP      A+P P AA   G  GAAP   PA
Sbjct: 276 APATLARPPGHPA---GPP--TAAPAVPPPAAAQNGGSAGAAPAPAPA 318



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 41/123 (33%), Positives = 47/123 (38%), Gaps = 10/123 (8%)

Query: 414 APTARGLEGRQVVPPPP-PAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSR--- 469
           AP A         P P  PA  P P   AP  LA      A P   A    PPA ++   
Sbjct: 248 APPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGG 307

Query: 470 SALAHPISLMTLPGEAGAAGLAPPGHAAAFGGP------PGGLLLDALPGPYAAAAAGPL 523
           SA A P       G AG +G   PG AAA   P      P  ++  A P     AA+GP 
Sbjct: 308 SAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPA 367

Query: 524 GAA 526
             A
Sbjct: 368 STA 370



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 43/114 (37%), Positives = 46/114 (40%), Gaps = 15/114 (13%)

Query: 425 VVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGE 484
           V   P PAP  GP   A G  ALA  A A PG G  P   P P     A P +  TL G 
Sbjct: 146 VAAGPEPAPA-GPAKPA-GPAALA--ARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGS 201

Query: 485 AGAAG---LAPPGHAAAFGGPPGGLLL--DALPG------PYAAAAAGPLGAAP 527
           A        A P  +    GP   L L   A PG      P+  AAA P  AAP
Sbjct: 202 AALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAP 255



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 46/141 (32%), Positives = 54/141 (38%), Gaps = 22/141 (15%)

Query: 400 VNGDFATHCGDFEKAPTARGLEGRQVVPPPPPAPRPG--------------PVLGAPGEL 445
           V+G  A   G    AP A G  G    PPP    RPG              P++  P   
Sbjct: 63  VSGSPAGAAGAGPAAP-AEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLV--PAGP 119

Query: 446 ALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGG 505
           A   A    P +G+A    P P+ +A+A        P  AG A  A P   AA  GP  G
Sbjct: 120 APPAAKLRPPPEGSAGSCAPVPAAAAVAAGPE----PAPAGPAKPAGPAALAARAGPGPG 175

Query: 506 LLLDALPGPYAAAAAGPLGAA 526
                 PGP     AGP GAA
Sbjct: 176 PGPGPGPGPGPGKPAGP-GAA 195



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 35/115 (30%), Positives = 40/115 (34%), Gaps = 19/115 (16%)

Query: 426 VPPPPPA---------PRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPI 476
           VPPP  A         P P P  G P         +  PG GAA  A PAP   A +   
Sbjct: 297 VPPPAAAQNGGSAGAAPAPAPAAGGP------AGVSGQPGPGAAA-AAPAPGVKAESPKR 349

Query: 477 SLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRFP 531
            +   P  A     + P   AA     G  +  ALP P  AA   P    P   P
Sbjct: 350 VVQAAPPAAQTLAASGPASTAA-SMVIGPTMQGALPSP--AAVPPPAPGTPTGLP 401



 Score = 30.0 bits (66), Expect = 6.2
 Identities = 32/88 (36%), Positives = 36/88 (40%), Gaps = 11/88 (12%)

Query: 443 GELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGE-AGAAGLAPPGHAAAFGG 501
           G L    AA+A      AP  P    R+A A  +    + G  AGAAG  P   AA   G
Sbjct: 27  GSLESQLAASAAHHHHLAPRTPEV--RAAAAGALGNHVVSGSPAGAAGAGP---AAPAEG 81

Query: 502 PPGGLLLDALPGPYAAAAAGPLGAAPDR 529
            PG     A P P  A  A P G  P R
Sbjct: 82  APG-----AAPEPPPAGRARPGGGGPQR 104


>gi|50345831 forkhead box J3 [Homo sapiens]
          Length = 622

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 23/47 (48%), Positives = 32/47 (68%), Gaps = 5/47 (10%)

Query: 92  SYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKGDSNSSAGWK 138
           SYA LIT AI S+P K++TLS+IY W+    PY+++ G     +GWK
Sbjct: 82  SYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAG-----SGWK 123


>gi|119508426 alpha 3 type IX collagen [Homo sapiens]
          Length = 684

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 52/176 (29%), Positives = 61/176 (34%), Gaps = 39/176 (22%)

Query: 415 PTARGLEGRQVVP--PPPPAPRPGPVL-GAPGELALAGAAAA--YPGKGAAPYAPPAPS- 468
           P   G++G    P  P PP P+  P   G PGE  L G        G+   P    AP  
Sbjct: 43  PGQDGIDGEAGPPGLPGPPGPKGAPGKPGKPGEAGLPGLPGVDGLTGRDGPPGPKGAPGE 102

Query: 469 RSALAHP----ISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLG 524
           R +L  P    +    LPG  G AG++ P       GPPG   L  LPGP      GP G
Sbjct: 103 RGSLGPPGPPGLGGKGLPGPPGEAGVSGPPGGIGLRGPPGPSGLPGLPGP-----PGPPG 157

Query: 525 AAPDRFPADLDLDMFSGSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAP 580
             P   P                        +     D    S  PP PPG  G P
Sbjct: 158 --PPGHPG----------------------VLPEGATDLQCPSICPPGPPGPPGMP 189



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 34/109 (31%), Positives = 45/109 (41%), Gaps = 10/109 (9%)

Query: 414 APTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALA 473
           AP  RG +G++     P  P P  + G  G+    GAA     +G A  +   P      
Sbjct: 398 APGVRGFQGQKGSMGDPGLPGPQGLRGDVGDRGPGGAAGPKGDQGIAG-SDGLPGDKGEL 456

Query: 474 HPISLMTLPGEAGAAG-LAPPGHAAAFG--------GPPGGLLLDALPG 513
            P  L+   GE+G+ G L P G     G        GPPG L L  +PG
Sbjct: 457 GPSGLVGPKGESGSRGELGPKGTQGPNGTSGVQGVPGPPGPLGLQGVPG 505



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 48/168 (28%), Positives = 54/168 (32%), Gaps = 49/168 (29%)

Query: 430 PPAPRPGPVLGAPGELALAGAA--AAYPGKGAAPYAPPAPSRSAL---AHPISLMTLPGE 484
           P A  P  +L   GEL  A  A     PG    P  P  P +  +   A P  L   PG 
Sbjct: 4   PRACAPLLLLLLLGELLAAAGAQRVGLPGPPGPPGPPGKPGQDGIDGEAGPPGLPGPPGP 63

Query: 485 AGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRFPADLDLDMFSGSLE 544
            GA G       A   G PG   L    GP      GP GA  +R           GSL 
Sbjct: 64  KGAPGKPGKPGEAGLPGLPGVDGLTGRDGP-----PGPKGAPGER-----------GSLG 107

Query: 545 CDVESIILNDFMDSDEMDFNFDSALPPPPPGLAG---APPPNQSWVPG 589
                                    PP PPGL G     PP ++ V G
Sbjct: 108 -------------------------PPGPPGLGGKGLPGPPGEAGVSG 130


>gi|8923842 forkhead box J2 [Homo sapiens]
          Length = 574

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 24/47 (51%), Positives = 31/47 (65%), Gaps = 5/47 (10%)

Query: 92  SYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKGDSNSSAGWK 138
           SYA LIT AI S+P K++TLS+IY W+    PY+K     N+  GWK
Sbjct: 70  SYATLITYAINSSPAKKMTLSEIYRWICDNFPYYK-----NAGIGWK 111


>gi|39812378 RAN binding protein 9 [Homo sapiens]
          Length = 729

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 42/128 (32%), Positives = 52/128 (40%), Gaps = 18/128 (14%)

Query: 415 PTARGLEGRQVVPPPPPAPRP--GPVLGAPGELALAGAAAAYPGKGAA------------ 460
           P  +  + +Q+ PPPP A  P  G VL AP  ++   + A  PG GA             
Sbjct: 9   PPQQQQQQQQLSPPPPAALAPVSGVVLPAPPAVSAGSSPAGSPGGGAGGEGLGAAAAALL 68

Query: 461 --PYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPG--HAAAFGGPPGGLLLDALPGPYA 516
             P  PP P+ +A   P      P  A A    PP     AA  GP GG    AL    +
Sbjct: 69  LHPPPPPPPATAAPPPPPPPPPPPASAAAPASGPPAPPGLAAGPGPAGGAPTPALVAGSS 128

Query: 517 AAAAGPLG 524
           AAA  P G
Sbjct: 129 AAAPFPHG 136


>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
          Length = 1682

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 51/168 (30%), Positives = 58/168 (34%), Gaps = 32/168 (19%)

Query: 427 PPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAP----YAPP--APSRSALAHPISLMT 480
           PPPPP P PG     P +L   G  +   G    P     APP     R +L HP     
Sbjct: 258 PPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHP----- 312

Query: 481 LPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRFPADLDLDMFS 540
            P  A A    PPGH      PPG       PGP    A    G  P   P   DL    
Sbjct: 313 YPYPAPAYTAHPPGHRLVPAAPPG-------PGPRPPGAESH-GCLPATRPPGSDLR--- 361

Query: 541 GSLECDVESIILNDFMDSDEMDFNFDSAL---PPPPPGLAGAPPPNQS 585
                  ES +    MDS        + +   P  PPGL G    + S
Sbjct: 362 -------ESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSS 402



 Score = 37.0 bits (84), Expect = 0.051
 Identities = 28/89 (31%), Positives = 36/89 (40%), Gaps = 7/89 (7%)

Query: 415 PTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAH 474
           P A+     Q  PPPPP P P  +L +   + L G    Y G GAA    P P       
Sbjct: 780 PLAKFPPPSQPQPPPPPPPSPASLLKSLASV-LEGQKYCYRGTGAAVSTRPGPL------ 832

Query: 475 PISLMTLPGEAGAAGLAPPGHAAAFGGPP 503
           P +  +    +GA  L P   A +  G P
Sbjct: 833 PTTQYSPGPPSGATALPPTSAAPSAQGSP 861



 Score = 30.0 bits (66), Expect = 6.2
 Identities = 32/119 (26%), Positives = 43/119 (36%), Gaps = 19/119 (15%)

Query: 423 RQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKG-AAPYAPPAPSRSA-LAHPISLMT 480
           R + PPPPPA   GP   A  E         +  +G   P  PP P R   L  P S  +
Sbjct: 475 RLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFS 534

Query: 481 LPGEAGAAGLAPP------------GHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAP 527
           +  +       PP             H+++  GP     +   P PY A +  PL   P
Sbjct: 535 VGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGP-----VSFPPPPYLARSIDPLPRPP 588


>gi|134142824 forkhead box D2 [Homo sapiens]
          Length = 495

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 44/144 (30%), Positives = 55/144 (38%), Gaps = 36/144 (25%)

Query: 423 RQVVPPPPPAPRPGPVLGAPGELALAGAAAAY-----------------------PGKGA 459
           RQ +PPP P P P P L   G  A AG   A+                       P  G 
Sbjct: 225 RQPLPPPHPHPHPHPELLLRGGAAAAGDPGAFLPGFAAYGAYGYGYGLALPAYGAPPPGP 284

Query: 460 APYAPPAP-----SRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGP 514
           AP+  P P     + +A A P  L   PG A A    PP  A+ F G        + P P
Sbjct: 285 APHPHPHPHAFAFAAAAAAAPCQLSVPPGRAAAPPPGPP-TASVFAG------AGSAPAP 337

Query: 515 YAAAAAGPLGAAPDRFPADLDLDM 538
             A+ +GP G  P   PA L  ++
Sbjct: 338 APASGSGP-GPGPAGLPAFLGAEL 360



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 92/365 (25%), Positives = 122/365 (33%), Gaps = 99/365 (27%)

Query: 31  QPDLAGDED-------------GALGAGVAEGAEDCGPERRATAPAMAPAPPLG--AEVG 75
           + DLA DE+              + GA  A G+   G      A    P PP G  A   
Sbjct: 64  EADLAEDEEESGGCSDGEPRALASRGAAAAAGSPGPGAAAARGAAGPGPGPPSGGAATRS 123

Query: 76  PLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKDKGDS-NSS 134
           PL K            SY  LIT AI  +P KRLTLS+I +++    PY+++K  +  +S
Sbjct: 124 PLVKPP---------YSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNS 174

Query: 135 AGWKVGASGWGGGWGRRLGLPGAARCVGLQEG-----------RQKEGFLAPPGVTESCS 183
               +  +       R  G PG      L              R+++ F   P +     
Sbjct: 175 IRHNLSLNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRKRFKRQP-LPPPHP 233

Query: 184 SRAPSSSFVLRGSPAPRADGGGEVTFPEVATCEVVDLGIG-------------------- 223
              P    +LRG  A   D G     P  A       G G                    
Sbjct: 234 HPHPHPELLLRGGAAAAGDPG--AFLPGFAAYGAYGYGYGLALPAYGAPPPGPAPHPHPH 291

Query: 224 PQARAF-----------SVPLGAS------------LQGWGTAAGPSPELGSGQGWLPFY 260
           P A AF           SVP G +              G G+A  P+P  GSG G  P  
Sbjct: 292 PHAFAFAAAAAAAPCQLSVPPGRAAAPPPGPPTASVFAGAGSAPAPAPASGSGPGPGP-- 349

Query: 261 PFSTADPSAEDLHMASGPWHHPGHIFCQEEAWTENLNFTPDGRANGLPRA-LNQGLQRTR 319
                         A  P      + C +  +  +L+    G A GLP A L QGL+   
Sbjct: 350 --------------AGLPAFLGAELGCAKAFYAASLSPPAAGTAAGLPTALLRQGLKTDA 395

Query: 320 QGKAG 324
            G AG
Sbjct: 396 GGGAG 400



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 48/131 (36%), Positives = 50/131 (38%), Gaps = 23/131 (17%)

Query: 415 PTARGLEGRQVVPPPPPA----PRPGPVLGAPGEL-ALAGAAAAY-------PGKGAAPY 462
           PTA    G    P P PA    P PGP  G P  L A  G A A+       P  G A  
Sbjct: 323 PTASVFAGAGSAPAPAPASGSGPGPGPA-GLPAFLGAELGCAKAFYAASLSPPAAGTAAG 381

Query: 463 APPAPSRSALAHPISLMTLPGEAGAAGLAPP-------GHAAAFGGPPGGLLLDALPGPY 515
            P A  R  L          G AG AG  P        GH      PPG    +  PGP 
Sbjct: 382 LPTALLRQGLKTDAGGGAGGGGAG-AGQRPSFSIDHIMGHGGGGAAPPGA--GEGSPGPP 438

Query: 516 AAAAAGPLGAA 526
            AAAAGP G A
Sbjct: 439 FAAAAGPGGQA 449


>gi|116256354 alpha 2 type IV collagen preproprotein [Homo sapiens]
          Length = 1712

 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 45/120 (37%), Positives = 51/120 (42%), Gaps = 12/120 (10%)

Query: 418 RGLEGRQVVPPPP--PAPRPGPVL--GAPGELALAGAAAAYPGKGAAPYAP--PAPSRSA 471
           RG +G    P PP  PA  P P L  GA G+    GA    PG    P  P  P P   +
Sbjct: 334 RGPKGEAGDPGPPGLPAYSPHPSLAKGARGDPGFPGAQGE-PGSQGEPGDPGLPGPPGLS 392

Query: 472 LAHPISLMTLPGEAGAAG-LAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRF 530
           +        LPGE G  G +  PG  A +GGPPG       PGP      GP G  PD F
Sbjct: 393 IGDGDQRRGLPGEMGPKGFIGDPGIPALYGGPPGPDGKRGPPGP--PGLPGPPG--PDGF 448



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 38/120 (31%), Positives = 47/120 (39%), Gaps = 24/120 (20%)

Query: 428  PPPPAPR---------PGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISL 478
            P PP  R         PGPV G PG+    GA    PG+   P +P       +  P ++
Sbjct: 1222 PGPPGERGDPGEANTLPGPV-GVPGQKGDQGA----PGERGPPGSPGLQGFPGITPPSNI 1276

Query: 479  MTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPG-------PYAAAAAGPLGAAPDRFP 531
               PG+ GA G+        + GPPG     ALPG       P A    G  G A D  P
Sbjct: 1277 SGAPGDKGAPGIF---GLKGYRGPPGPPGSAALPGSKGDTGNPGAPGTPGTKGWAGDSGP 1333



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 43/142 (30%), Positives = 50/142 (35%), Gaps = 36/142 (25%)

Query: 418 RGLEGRQVVPPPPPAPRPGPVLGAPGEL--------ALAG--AAAAYPGKGAAPYAPPAP 467
           RG  G   +P PP    P    G PG++        A+ G    A  PG    P   P  
Sbjct: 632 RGFPGDAGLPGPPGFLGPPGPAGTPGQIDCDTDVKRAVGGDRQEAIQPGCIGGPKGLP-- 689

Query: 468 SRSALAHPISLMTLPGEAGAAGL-APPGHAAAFGGP-----PGGLLLDALPGPYAAAAAG 521
                     L   PG  GA GL   PG A A GGP     PG    +  PGP      G
Sbjct: 690 ---------GLPGPPGPTGAKGLRGIPGFAGADGGPGPRGLPGDAGREGFPGP--PGFIG 738

Query: 522 PLGA-------APDRFPADLDL 536
           P G+        PD  P  + L
Sbjct: 739 PRGSKGAVGLPGPDGSPGPIGL 760



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 43/132 (32%), Positives = 48/132 (36%), Gaps = 25/132 (18%)

Query: 414 APTARGLEGRQVVPPPPPAPR--PGPVLGA-PGELALAGAAAAYPGKGAAPYAPPAPSRS 470
           +P   GL G    P  PP  R  PG VLGA PG    AG       KG      P   R 
Sbjct: 754 SPGPIGLPG----PDGPPGERGLPGEVLGAQPGPRGDAGVPGQPGLKGLPGDRGPPGFRG 809

Query: 471 ALAHP-----ISLMTLPGEAGAAGLAPPGHAAAFGGPP---GGLLLDALPG--------- 513
           +   P          LPG +G  GL  P     F G P   G L L  +PG         
Sbjct: 810 SQGMPGMPGLKGQPGLPGPSGQPGLYGPPGLHGFPGAPGQEGPLGLPGIPGREGLPGDRG 869

Query: 514 -PYAAAAAGPLG 524
            P    A GP+G
Sbjct: 870 DPGDTGAPGPVG 881



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 34/106 (32%), Positives = 44/106 (41%), Gaps = 12/106 (11%)

Query: 128  KGDS-NSSAGWKVGASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRA 186
            KGD+ N  A    G  GW G  G + G PG     G +  R ++GF+   G T +   R 
Sbjct: 1310 KGDTGNPGAPGTPGTKGWAGDSGPQ-GRPGVFGLPGEKGPRGEQGFMGNTGPTGAVGDRG 1368

Query: 187  PSSSFVLRGSPA-PRADGGGEVTFPEVA----TCEVVDLGIGPQAR 227
            P      +G P  P A   G V  P +A       V    +GPQ R
Sbjct: 1369 PKGP---KGDPGFPGAP--GTVGAPGIAGIPQKIAVQPGTVGPQGR 1409



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 36/125 (28%), Positives = 45/125 (36%), Gaps = 16/125 (12%)

Query: 419 GLEGRQVVPPPPPAP-RPGP------VLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSA 471
           G +G++  P PP  P  PGP      + GA G     G   +   +G   +   A     
Sbjct: 426 GPDGKRGPPGPPGLPGPPGPDGFLFGLKGAKGRAGFPGLPGSPGARGPKGWKGDAGECRC 485

Query: 472 LAHPISLMTLPGEAGAAGLA----PPGHAAAFGGPPGGLLLDALPG----PYAAAAAGPL 523
                ++  LPG  G  G A     PG      G PG   L   PG    P    A GP 
Sbjct: 486 TEGDEAIKGLPGLPGPKGFAGINGEPGRKGD-RGDPGQHGLPGFPGLKGVPGNIGAPGPK 544

Query: 524 GAAPD 528
           GA  D
Sbjct: 545 GAKGD 549



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 33/122 (27%), Positives = 38/122 (31%), Gaps = 11/122 (9%)

Query: 414 APTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAG--------AAAAYPGKGAAPYAPP 465
           A   R  EG + +   P  P P    G  GE    G            +PG    P    
Sbjct: 480 AGECRCTEGDEAIKGLPGLPGPKGFAGINGEPGRKGDRGDPGQHGLPGFPGLKGVPGNIG 539

Query: 466 APSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLD---ALPGPYAAAAAGP 522
           AP           +T  GE G  G+          G PG   LD    LPGP      GP
Sbjct: 540 APGPKGAKGDSRTITTKGERGQPGVPGVPGMKGDDGSPGRDGLDGFPGLPGPPGDGIKGP 599

Query: 523 LG 524
            G
Sbjct: 600 PG 601



 Score = 30.0 bits (66), Expect = 6.2
 Identities = 29/95 (30%), Positives = 35/95 (36%), Gaps = 6/95 (6%)

Query: 412  EKAPTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGA--AAAYPGKGAAPYAPP-APS 468
            +K     G  G Q    PP AP      G PGE    GA   A   G+G     P     
Sbjct: 1395 QKIAVQPGTVGPQGRRGPPGAPGEMGPQGPPGEPGFRGAPGKAGPQGRGGVSAVPGFRGD 1454

Query: 469  RSALAH--PISLMTLPGEAGAAGL-APPGHAAAFG 500
               + H  PI     PG  G+ GL   PG + + G
Sbjct: 1455 EGPIGHQGPIGQEGAPGRPGSPGLPGMPGRSVSIG 1489


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 43/117 (36%), Positives = 45/117 (38%), Gaps = 22/117 (18%)

Query: 415 PTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAH 474
           P   G +GR   P PP A     V+G PG    AG     PGK      P  P     A 
Sbjct: 556 PGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGE----PGKAGERGVPGPPGAVGPAG 611

Query: 475 PISLMTLPGEAGAAGLAPPGHAAAFG-----GPPGGLLLDALPGPYAAAAAGPLGAA 526
                   GEAGA G  PPG A   G     GP G      LPGP     AGP G A
Sbjct: 612 K------DGEAGAQG--PPGPAGPAGERGEQGPAGSPGFQGLPGP-----AGPPGEA 655



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 109/402 (27%), Positives = 134/402 (33%), Gaps = 93/402 (23%)

Query: 140 GASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRAPSSSFVLRGSPAP 199
           G +G  G  G R G PG     G    R   G    PG       + P+     RGSP P
Sbjct: 461 GPAGEEGKRGAR-GEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGE---RGSPGP 516

Query: 200 RADGG--GEVTFPEVATCEVVDLGIGPQARAFSVPLGASLQGWGTAAGPSPELG----SG 253
               G  GE   P  A                 +P    L G   + GP  + G    +G
Sbjct: 517 AGPKGSPGEAGRPGEA----------------GLPGAKGLTGSPGSPGPDGKTGPPGPAG 560

Query: 254 QGWLPFYPFSTADPSAEDLHMASGPWHHPGHIFCQEEAWTENLNFTPDGRANGLPRALNQ 313
           Q   P  P     P A      +G    PG      E         P     G P A+  
Sbjct: 561 QDGRPGPP---GPPGARG---QAGVMGFPGPKGAAGEPGKAGERGVP-----GPPGAVGP 609

Query: 314 GLQRTRQGKAGKSQLLPSKARKCQRQGAWGPEESDQCLELGQYLDQEVEATRTGLAKAGS 373
                + G+AG +Q  P  A     +G  GP  S     L        EA + G      
Sbjct: 610 A---GKDGEAG-AQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPG 665

Query: 374 DMGSTGDWHSRIKKRMYGEMAEVFWRVNGDFATHCGDFEKAPTARGLEGRQVVPPPPPAP 433
           D+G+ G   +R ++   GE                         RG++G    PP P  P
Sbjct: 666 DLGAPGPSGARGERGFPGE-------------------------RGVQG----PPGPAGP 696

Query: 434 RPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEAGAAGLAPP 493
           R     GAPG     G A A PG   AP +  AP          L  +PGE GAAGL  P
Sbjct: 697 RGAN--GAPGNDGAKGDAGA-PG---APGSQGAPG---------LQGMPGERGAAGLPGP 741

Query: 494 ----GHAAAFG--GPPGGLLLDALPGPYAAAAAGPLGAAPDR 529
               G A   G  G PG   +  L GP      GP GA  D+
Sbjct: 742 KGDRGDAGPKGADGSPGKDGVRGLTGP--IGPPGPAGAPGDK 781



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 44/116 (37%), Positives = 49/116 (42%), Gaps = 13/116 (11%)

Query: 418 RGLEGRQVVPPPPPAPRPGPV--LGAPGELALAGAAAAYPGKGAAPYAPPAPSR-----S 470
           RGL G   + PP PA  PG     G  G     GA  A PG    P  PP P+       
Sbjct: 763 RGLTGP--IGPPGPAGAPGDKGESGPSGPAGPTGARGA-PGDRGEP-GPPGPAGFAGPPG 818

Query: 471 ALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAA-AAAGPLGA 525
           A   P      PG+AGA G A P   A   GPPG +     PG   A  +AGP GA
Sbjct: 819 ADGQP-GAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGA 873



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 43/125 (34%), Positives = 45/125 (36%), Gaps = 19/125 (15%)

Query: 417 ARGLEGRQVVPPPP-PAPRPGPV-----LGAPGELALAGAAA-AYPGKGAAPYAPPAP-- 467
           ARG  G +  P PP PA   GP       GA GE   AGA   A P   A P  PP P  
Sbjct: 795 ARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIG 854

Query: 468 --------SRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAA 519
                        A P      PG AG  G   P   A   GPPG    +   GP     
Sbjct: 855 NVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGP--RGE 912

Query: 520 AGPLG 524
            GP G
Sbjct: 913 TGPAG 917



 Score = 38.1 bits (87), Expect = 0.023
 Identities = 31/96 (32%), Positives = 38/96 (39%), Gaps = 14/96 (14%)

Query: 431  PAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEAGAAGL 490
            PA RPG V G PG    AG   + PG      AP  P    +A    ++ LPG+ G  G 
Sbjct: 915  PAGRPGEV-GPPGPPGPAGEKGS-PGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGF 972

Query: 491  AP------------PGHAAAFGGPPGGLLLDALPGP 514
                          P  A+   GPPG +    L GP
Sbjct: 973  PGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGP 1008



 Score = 37.7 bits (86), Expect = 0.030
 Identities = 37/118 (31%), Positives = 40/118 (33%), Gaps = 16/118 (13%)

Query: 415 PTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAY--------PGKGAAPYAPPA 466
           P   G  G + +P PP AP P    G PGE    GA+           PGK         
Sbjct: 178 PGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGK 237

Query: 467 PSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLG 524
           P R     P      PG  GA GL          G  G   LD   G   A  AGP G
Sbjct: 238 PGRPGERGP------PGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGD--AGPAGPKG 287



 Score = 37.7 bits (86), Expect = 0.030
 Identities = 44/125 (35%), Positives = 49/125 (39%), Gaps = 13/125 (10%)

Query: 418 RGLEGRQVVP----PPPPAPRPGPV--LGAPGELALAGAAAAYPGKGAAPYAPPAPSRSA 471
           RG EG Q V     PP PA   GP    GA G+    GA  A PG   AP  P A   S 
Sbjct: 361 RGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGA-PGIAGAPGFPGARGPSG 419

Query: 472 LAHPISLMTLPGEAGAAGLAPPGHAAAFG--GPPGGLLLDALPGPYAAAAAGPLGAAPDR 529
              P       G +G  G   PG     G  G PG + +   PGP  A   G  GA  + 
Sbjct: 420 PQGPGGPPGPKGNSGEPG--APGSKGDTGAKGEPGPVGVQGPPGP--AGEEGKRGARGEP 475

Query: 530 FPADL 534
            P  L
Sbjct: 476 GPTGL 480



 Score = 37.7 bits (86), Expect = 0.030
 Identities = 112/443 (25%), Positives = 138/443 (31%), Gaps = 84/443 (18%)

Query: 127  DKGDSNSSA-GWKVGASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSR 185
            DKG+S  S      GA G  G  G   G PG A            GF  PPG      ++
Sbjct: 780  DKGESGPSGPAGPTGARGAPGDRGEP-GPPGPA------------GFAGPPGADGQPGAK 826

Query: 186  APSSSFVLRGSPAPRADGGGEVTFPEVATCEVVDLGI--GPQARAFSVPLGASLQGWGTA 243
                    +G   P    G     P      + ++G      AR  + P GA+  G+  A
Sbjct: 827  GEPGDAGAKGDAGPPGPAG-----PAGPPGPIGNVGAPGAKGARGSAGPPGAT--GFPGA 879

Query: 244  AGP-SPELGSGQGWLPFYPFSTADPSAEDLHMASGPWHHPGHIFCQEEAWTENLNFTP-- 300
            AG   P   SG    P  P        +     +GP   PG +             +P  
Sbjct: 880  AGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGA 939

Query: 301  DGRANGLPRALNQGLQRTRQGKAGKSQLLPSKARKCQRQGAWGPEESDQCLELGQYLDQE 360
            DG A        QG+   R G  G    LP +  +    G  GP                
Sbjct: 940  DGPAGAPGTPGPQGIAGQR-GVVG----LPGQRGERGFPGLPGPSG-------------- 980

Query: 361  VEATRTGLAKAGSDMGSTGDWHSRIKKRMYGEMAEVFWRVNGDFATHCGDFEKAPTARGL 420
             E  + G + A  + G  G           GE      R     A      + +P A+G 
Sbjct: 981  -EPGKQGPSGASGERGPPGPMGPPGLAGPPGESG----REGAPGAEGSPGRDGSPGAKGD 1035

Query: 421  EGRQVVPPPPPAP----RPGPV-----LGAPGELALAGAAAAYPGKGAAPYAPPAPSR-- 469
             G      PP AP     PGPV      G  GE   AG A      GA   A P   R  
Sbjct: 1036 RGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGD 1095

Query: 470  ------------------SALAHPISLMTLPGE---AGAAGLAPPGHAAAFGGPPGGLLL 508
                              S L  P      PGE   +GA+G A P       G PG   L
Sbjct: 1096 KGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGL 1155

Query: 509  DALPGPYAAAAAGPLGAAPDRFP 531
            + LPGP      GP G   D  P
Sbjct: 1156 NGLPGP--IGPPGPRGRTGDAGP 1176



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 37/107 (34%), Positives = 42/107 (39%), Gaps = 17/107 (15%)

Query: 428  PPPPAPRPGPVLGAPGELALAGA--AAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEA 485
            PP P   PG + G PGE    GA  A   PG+  +P A      +  A P      PG  
Sbjct: 996  PPGPMGPPG-LAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGP------PGAP 1048

Query: 486  GAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRFPA 532
            GA G   P   A   G  G        GP  A  AGP+G    R PA
Sbjct: 1049 GAPGAPGPVGPAGKSGDRGE------TGP--AGPAGPVGPVGARGPA 1087



 Score = 36.6 bits (83), Expect = 0.066
 Identities = 44/147 (29%), Positives = 53/147 (36%), Gaps = 26/147 (17%)

Query: 418  RGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAA--AAYPGKGAAPYAPPAPSRSALAHP 475
            RG  G Q  P PP         G+PGE   +GA+  A   G   +  AP     + L  P
Sbjct: 1111 RGFSGLQGPPGPP---------GSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGLPGP 1161

Query: 476  ISLMTLPGEAGAAG----LAPPGHAAAFGGPPGGLLLDALPGPYAAAA--------AGPL 523
            I      G  G AG      PPG     G P  G     LP P    A        A   
Sbjct: 1162 IGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHDGGRYYRADDA 1221

Query: 524  GAAPDRFPADLDLDMFSGSLECDVESI 550
                DR   DL++D    SL   +E+I
Sbjct: 1222 NVVRDR---DLEVDTTLKSLSQQIENI 1245



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 36/111 (32%), Positives = 40/111 (36%), Gaps = 24/111 (21%)

Query: 419 GLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAA-----AYPGKGAAPYAPPAPSRSALA 473
           G  GR  +P  P  P P    G PG   L G  A      Y  K     + P P      
Sbjct: 127 GPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGP-----M 181

Query: 474 HPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLG 524
            P     LPG  GA G  P G    F GPPG         P    A+GP+G
Sbjct: 182 GPSGPRGLPGPPGAPG--PQG----FQGPPG--------EPGEPGASGPMG 218



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 36/111 (32%), Positives = 38/111 (34%), Gaps = 6/111 (5%)

Query: 418 RGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPIS 477
           RGL G +     P AP P    G  G    AG      G    P  P A      A P  
Sbjct: 304 RGLPGER---GRPGAPGPAGARGNDGATGAAGPPGP-TGPAGPPGFPGAVGAKGEAGPQG 359

Query: 478 LMTLPGEAGAAGL-APPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAP 527
                G  G  G   PPG A A  GP G    D  PG   A  A  +  AP
Sbjct: 360 PRGSEGPQGVRGEPGPPGPAGA-AGPAGNPGADGQPGAKGANGAPGIAGAP 409



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 39/119 (32%), Positives = 44/119 (36%), Gaps = 13/119 (10%)

Query: 415 PTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAA--AAYPGKGAAPYAPPAPSRSAL 472
           P A G +G      P  +  P  V G PG    AGAA  A  PG    P A  A     +
Sbjct: 346 PGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGI 405

Query: 473 AHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDRFP 531
           A        PG  GA G   P      GGPPG       PG  A  + G  GA  +  P
Sbjct: 406 A------GAPGFPGARG---PSGPQGPGGPPGPKGNSGEPG--APGSKGDTGAKGEPGP 453



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 31/112 (27%), Positives = 37/112 (33%), Gaps = 17/112 (15%)

Query: 417 ARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPI 476
           ARG +G      PP    P    G PG +   G A     +G+               P 
Sbjct: 321 ARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGS-------------EGPQ 367

Query: 477 SLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPG----PYAAAAAGPLG 524
            +   PG  G AG A P       G PG    +  PG    P    A GP G
Sbjct: 368 GVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSG 419



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 37/113 (32%), Positives = 41/113 (36%), Gaps = 17/113 (15%)

Query: 427 PPPPPAPRPGP-VLGAPGELALAGAAAAYPGKGAAPYAPP-----APSRSALAHPISLMT 480
           PP P   R  P   G PG     G +     KG A  A P     +P  +     +    
Sbjct: 246 PPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRG 305

Query: 481 LPGEAGAAGLAPPGHAAAFG--------GPPGGLLLDALPG-PYAAAAAGPLG 524
           LPGE G  G   PG A A G        GPPG       PG P A  A G  G
Sbjct: 306 LPGERGRPG--APGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAG 356



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 39/111 (35%), Positives = 45/111 (40%), Gaps = 28/111 (25%)

Query: 419 GLEGRQV-VPPPPPAPRPGPV--LGAPGELALAGAAAAYPGKGAAPYAP-PAPSRSALAH 474
           GL+G +    P  P   PG     GAPG++   G     PG+   P AP PA +R     
Sbjct: 272 GLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGL----PGERGRPGAPGPAGARGN--- 324

Query: 475 PISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAA-AAAGPLG 524
                   G  GAAG  PPG      GPPG       PG   A   AGP G
Sbjct: 325 -------DGATGAAG--PPGPTGP-AGPPG------FPGAVGAKGEAGPQG 359


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 40/118 (33%), Positives = 47/118 (39%), Gaps = 12/118 (10%)

Query: 417 ARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYP-----GKGAAPYAPPAPSRSA 471
           A G  G Q +P PP  P  G   G PG+  + G A A       G+   P    +P    
Sbjct: 658 APGPSGFQGLPGPPGPPGEG---GKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQG 714

Query: 472 LAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAA-AGPLGAAPD 528
           L  P  L   PG  G  G + P       GPPG   L  +PG   AA  AGP G   D
Sbjct: 715 LQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPG---LQGMPGERGAAGIAGPKGDRGD 769



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 110/404 (27%), Positives = 134/404 (33%), Gaps = 68/404 (16%)

Query: 138 KVGASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRAPSSSFVLRGSP 197
           K GA G  GG G  +G PG     G +    ++G   P G       R PS    L G  
Sbjct: 490 KRGARGEPGGVGP-IGPPGERGAPGNRGFPGQDGLAGPKGAP---GERGPSG---LAGPK 542

Query: 198 APRADGG--GEVTFPEVATCEVVDLGIGPQARAFSVPLGASLQGWGTAAGPSPELGSGQG 255
               D G  GE   P            GPQ +    P GA  +  G    P P+   GQ 
Sbjct: 543 GANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVG--PSGAPGED-GRPGPPGPQGARGQP 599

Query: 256 WLPFYPFSTADPSAEDLHMASGPWHHPGHIFCQEEAWTENLNFTP--DGR--ANGLPRAL 311
            +  +P             A+G    PG    +       L   P  DG   A G P   
Sbjct: 600 GVMGFPGPKG---------ANG---EPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPA 647

Query: 312 NQGLQRTRQGKAGKSQLLPSKARKCQRQGAWGPEESDQCLELGQYLDQEV--EATRTGLA 369
               +R  QG  G S            QG  GP       E G+  DQ V  EA   GL 
Sbjct: 648 GPAGERGEQGAPGPSGF----------QGLPGPPGPPG--EGGKPGDQGVPGEAGAPGLV 695

Query: 370 KAGSDMGSTGDWHSRIKKRMYGEMAEVFWRVNGDFATHCGDFEKAPTARGLEGRQVVPPP 429
               + G  G+  S   + + G                       P   G +G      P
Sbjct: 696 GPRGERGFPGERGSPGAQGLQGPRG----------------LPGTPGTDGPKGASGPAGP 739

Query: 430 PPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPP--APSRSALAHPISLMTLPGEAGA 487
           P A  P  + G PGE   AG A     +G      P  AP +         +  PG AGA
Sbjct: 740 PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGA 799

Query: 488 AG----LAPPGHAAAFG--GPPGGLLLDALPGPYAAAAAGPLGA 525
            G    + PPG A + G  G PG       PGP  A  AGP GA
Sbjct: 800 NGEKGEVGPPGPAGSAGARGAPGERGETGPPGP--AGFAGPPGA 841



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 41/119 (34%), Positives = 49/119 (41%), Gaps = 16/119 (13%)

Query: 414 APTARGLEGRQ--VVPPPPPAPRPGPVL-GAPGELALAGAAAAYPGKGAA-----PYAPP 465
           A  ARG +G+     PP P  P  GP   GAPG    AG   A   +GA      P  P 
Sbjct: 340 AAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPG 399

Query: 466 APSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLG 524
           +P  +  +       +PG  G+AG      A  F GP G       PGP    A GPLG
Sbjct: 400 SPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP------PGP--QGATGPLG 450



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 42/126 (33%), Positives = 45/126 (35%), Gaps = 26/126 (20%)

Query: 415 PTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAG--AAAAYPGKGAAPYAPPA------ 466
           P   G +G Q    P   P P    GAPG     G   A   PG G  P  PP       
Sbjct: 458 PGIAGFKGEQ---GPKGEPGPAGPQGAPGPAGEEGKRGARGEPG-GVGPIGPPGERGAPG 513

Query: 467 ----PSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAA--- 519
               P +  LA P      PGE G +GLA P  A    G PG      LPG         
Sbjct: 514 NRGFPGQDGLAGPKGA---PGERGPSGLAGPKGANGDPGRPGE---PGLPGARGLTGRPG 567

Query: 520 -AGPLG 524
            AGP G
Sbjct: 568 DAGPQG 573



 Score = 38.1 bits (87), Expect = 0.023
 Identities = 42/133 (31%), Positives = 46/133 (34%), Gaps = 29/133 (21%)

Query: 414 APTARGLEGRQVVP--PPPPAPRPGPVLGAPGELALAGAAAAYPGKG------------- 458
           AP  RG +G    P  P PP P PGP    PG   L G  AA    G             
Sbjct: 145 APGPRGRDGEPGTPGNPGPPGP-PGP----PGPPGLGGNFAAQMAGGFDEKAGGAQLGVM 199

Query: 459 ------AAPYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALP 512
                   P  PP P  +    P      PGE G  G++ P       GPPG    D   
Sbjct: 200 QGPMGPMGPRGPPGP--AGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEA 257

Query: 513 G-PYAAAAAGPLG 524
           G P  A   GP G
Sbjct: 258 GKPGKAGERGPPG 270



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 42/136 (30%), Positives = 48/136 (35%), Gaps = 30/136 (22%)

Query: 414 APTARGLEGRQ--------VVPPPPPAPRPGPV-LGAPGELALAGAAAAYPGKGAAPYAP 464
           AP   G EG++        V P  PP  R  P   G PG+  LAG   A   +G +  A 
Sbjct: 481 APGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAG 540

Query: 465 PA--------PSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYA 516
           P         P    L     L   PG+AG  G   P  A    G PG       PGP  
Sbjct: 541 PKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGP------PGPQG 594

Query: 517 AAA-------AGPLGA 525
           A          GP GA
Sbjct: 595 ARGQPGVMGFPGPKGA 610



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 38/117 (32%), Positives = 41/117 (35%), Gaps = 11/117 (9%)

Query: 414 APTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALA 473
           AP  RGL G+        A  PGP  G  GE    GA    PG       P  P      
Sbjct: 625 APGLRGLPGKD--GETGAAGPPGPA-GPAGERGEQGA----PGPSGFQGLPGPPGPPGEG 677

Query: 474 HPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAA----GPLGAA 526
                  +PGEAGA GL  P     F G  G      L GP          GP GA+
Sbjct: 678 GKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGAS 734



 Score = 37.0 bits (84), Expect = 0.051
 Identities = 36/114 (31%), Positives = 42/114 (36%), Gaps = 14/114 (12%)

Query: 417 ARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKG----AAPYAPPAPSRSAL 472
           A G++G    P    +P P    G PGE    G A A   +G      P  PP P     
Sbjct: 304 APGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGP----- 358

Query: 473 AHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAA 526
             P      PG  GA G A P  A    GP G       PG     + GP GA+
Sbjct: 359 VGPAGGPGFPGAPGAKGEAGPTGAR---GPEGAQGPRGEPG--TPGSPGPAGAS 407



 Score = 37.0 bits (84), Expect = 0.051
 Identities = 113/446 (25%), Positives = 143/446 (32%), Gaps = 90/446 (20%)

Query: 140  GASGWGGGWGRR--LGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRA------PSSSF 191
            GA+G  G  G R  +G  G     G   GR   G + PPG   +   +       P+ S 
Sbjct: 756  GAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSA 815

Query: 192  VLRGSPAPRADGG--GEVTFPEVATCEVVDLGIGPQARAFSVPLGASLQGWGTAAGPSPE 249
              RG+P  R + G  G   F      +      G Q  A       +    G +  P P+
Sbjct: 816  GARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQ 875

Query: 250  LGSGQGWLPFYPFSTADPSAEDLHMASGPWHHPGHIFCQEEAWTENLNFTPDGRANGLPR 309
              +G         +   P A     A+G    PG           N N  P G     P 
Sbjct: 876  GPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPG----------SNGNPGPPGP----PG 921

Query: 310  ALNQGLQRTRQGKAGKSQLLPSKARKCQRQGAWGPEESDQCLELGQYLDQEVEATR---- 365
               +   +  +G +G     P +A +   QG  GP       E G+  D           
Sbjct: 922  PSGKDGPKGARGDSGP----PGRAGEPGLQGPAGPPG-----EKGEPGDDGPSGAEGPPG 972

Query: 366  -TGLAKAGSDMGSTGDWHSRIKKRMYGEMAEVFWRVNGDFATHCGDFEKAPTARGLEGRQ 424
              GLA     +G  G    R    + G   E                + AP A G  G  
Sbjct: 973  PQGLAGQRGIVGLPGQRGERGFPGLPGPSGEP-------------GKQGAPGASGDRGPP 1019

Query: 425  VVPPPP----PAPRPGPV--LGAPGELALAGAAAAYPGKG-----AAPYAPPAPSRSALA 473
                PP    PA  PG     GA G     GAA     +G      AP AP  P     A
Sbjct: 1020 GPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPA 1079

Query: 474  HPISLMTLPGEAGAAG-LAPPGHAAAFG--GPPG--------------GLL-------LD 509
             P       GEAGA G + P G A A G  GP G              GL        L 
Sbjct: 1080 GPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQ 1139

Query: 510  ALPGPYAAA----AAGPLGAAPDRFP 531
             LPGP   +    A+GP G +  R P
Sbjct: 1140 GLPGPPGPSGDQGASGPAGPSGPRGP 1165



 Score = 36.6 bits (83), Expect = 0.066
 Identities = 34/115 (29%), Positives = 40/115 (34%), Gaps = 3/115 (2%)

Query: 415 PTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAH 474
           P   G  G +  P PP  P      G PG+    G       +G  P  P  P       
Sbjct: 233 PGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGF-PGTPGLPGVKGHRG 291

Query: 475 PISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDR 529
              L    GEAGA G+     +    G PG +    LPG       GP GAA  R
Sbjct: 292 YPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPG--ERGRTGPAGAAGAR 344



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 47/155 (30%), Positives = 55/155 (35%), Gaps = 41/155 (26%)

Query: 415 PTARGLEGR--------QVVP---------PPPPAPR-----------PGPV-----LGA 441
           P ARGL GR        +V P         P PP P+           PGP       G 
Sbjct: 557 PGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGK 616

Query: 442 PGELALAGAAA--AYPGKGAAPYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAF 499
            GE  L GA      PGK     A   P  +  A        PG +G  GL  P      
Sbjct: 617 AGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGE 676

Query: 500 GGPPGGLLLDALPGPYAAAAAGPLGAAPDR-FPAD 533
           GG PG      +PG   A A G +G   +R FP +
Sbjct: 677 GGKPGD---QGVPG--EAGAPGLVGPRGERGFPGE 706



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 28/79 (35%), Positives = 31/79 (39%), Gaps = 9/79 (11%)

Query: 428 PPPPAPRPGP--VLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEA 485
           PP PA  PGP    G PGE    G +     +G  P  P  P     A        PG+A
Sbjct: 211 PPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGP-PGPPGKPGDDGEAGK------PGKA 263

Query: 486 GAAGLAPPGHAAAFGGPPG 504
           G  G   P  A  F G PG
Sbjct: 264 GERGPPGPQGARGFPGTPG 282



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 45/132 (34%), Positives = 50/132 (37%), Gaps = 28/132 (21%)

Query: 417 ARGLEGRQVVPPP--PPAPR--PGPV--LGAPGELALAGAAAAYPGKG----AAPYAPPA 466
           A G+ G    P P  PP P+   GP+   G  GE  +AG       KG    A P   P 
Sbjct: 424 APGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPG 483

Query: 467 PSRSALAHPISLMTLPGEAGAAG-LAPPGHAAAFG--GPPGGLLLDALPGPYAA------ 517
           P     A         GE G  G + PPG   A G  G PG    D L GP  A      
Sbjct: 484 P-----AGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPG---QDGLAGPKGAPGERGP 535

Query: 518 -AAAGPLGAAPD 528
              AGP GA  D
Sbjct: 536 SGLAGPKGANGD 547



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 36/116 (31%), Positives = 42/116 (36%), Gaps = 19/116 (16%)

Query: 418  RGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPI- 476
            RG  G Q +P PP         G  G+   +G A   P     P  P  PS    A+ I 
Sbjct: 1133 RGFTGLQGLPGPP---------GPSGDQGASGPAG--PSGPRGPPGPVGPSGKDGANGIP 1181

Query: 477  SLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGP----YAAAAAGPLGAAPD 528
              +  PG  G +G   P       GPPG       PGP     A A  GP    PD
Sbjct: 1182 GPIGPPGPRGRSGETGPAGPPGNPGPPGP---PGPPGPGIDMSAFAGLGPREKGPD 1234


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 40/118 (33%), Positives = 47/118 (39%), Gaps = 12/118 (10%)

Query: 417 ARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYP-----GKGAAPYAPPAPSRSA 471
           A G  G Q +P PP  P  G   G PG+  + G A A       G+   P    +P    
Sbjct: 589 APGPSGFQGLPGPPGPPGEG---GKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQG 645

Query: 472 LAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAA-AGPLGAAPD 528
           L  P  L   PG  G  G + P       GPPG   L  +PG   AA  AGP G   D
Sbjct: 646 LQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPG---LQGMPGERGAAGIAGPKGDRGD 700



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 110/404 (27%), Positives = 134/404 (33%), Gaps = 68/404 (16%)

Query: 138 KVGASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRAPSSSFVLRGSP 197
           K GA G  GG G  +G PG     G +    ++G   P G       R PS    L G  
Sbjct: 421 KRGARGEPGGVGP-IGPPGERGAPGNRGFPGQDGLAGPKGAP---GERGPSG---LAGPK 473

Query: 198 APRADGG--GEVTFPEVATCEVVDLGIGPQARAFSVPLGASLQGWGTAAGPSPELGSGQG 255
               D G  GE   P            GPQ +    P GA  +  G    P P+   GQ 
Sbjct: 474 GANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVG--PSGAPGED-GRPGPPGPQGARGQP 530

Query: 256 WLPFYPFSTADPSAEDLHMASGPWHHPGHIFCQEEAWTENLNFTP--DGR--ANGLPRAL 311
            +  +P             A+G    PG    +       L   P  DG   A G P   
Sbjct: 531 GVMGFPGPKG---------ANG---EPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPA 578

Query: 312 NQGLQRTRQGKAGKSQLLPSKARKCQRQGAWGPEESDQCLELGQYLDQEV--EATRTGLA 369
               +R  QG  G S            QG  GP       E G+  DQ V  EA   GL 
Sbjct: 579 GPAGERGEQGAPGPSGF----------QGLPGPPGPPG--EGGKPGDQGVPGEAGAPGLV 626

Query: 370 KAGSDMGSTGDWHSRIKKRMYGEMAEVFWRVNGDFATHCGDFEKAPTARGLEGRQVVPPP 429
               + G  G+  S   + + G                       P   G +G      P
Sbjct: 627 GPRGERGFPGERGSPGAQGLQGPRG----------------LPGTPGTDGPKGASGPAGP 670

Query: 430 PPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPP--APSRSALAHPISLMTLPGEAGA 487
           P A  P  + G PGE   AG A     +G      P  AP +         +  PG AGA
Sbjct: 671 PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGA 730

Query: 488 AG----LAPPGHAAAFG--GPPGGLLLDALPGPYAAAAAGPLGA 525
            G    + PPG A + G  G PG       PGP  A  AGP GA
Sbjct: 731 NGEKGEVGPPGPAGSAGARGAPGERGETGPPGP--AGFAGPPGA 772



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 41/119 (34%), Positives = 49/119 (41%), Gaps = 16/119 (13%)

Query: 414 APTARGLEGRQ--VVPPPPPAPRPGPVL-GAPGELALAGAAAAYPGKGAA-----PYAPP 465
           A  ARG +G+     PP P  P  GP   GAPG    AG   A   +GA      P  P 
Sbjct: 271 AAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPG 330

Query: 466 APSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLG 524
           +P  +  +       +PG  G+AG      A  F GP G       PGP    A GPLG
Sbjct: 331 SPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP------PGP--QGATGPLG 381



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 42/126 (33%), Positives = 45/126 (35%), Gaps = 26/126 (20%)

Query: 415 PTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAG--AAAAYPGKGAAPYAPPA------ 466
           P   G +G Q    P   P P    GAPG     G   A   PG G  P  PP       
Sbjct: 389 PGIAGFKGEQ---GPKGEPGPAGPQGAPGPAGEEGKRGARGEPG-GVGPIGPPGERGAPG 444

Query: 467 ----PSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAA--- 519
               P +  LA P      PGE G +GLA P  A    G PG      LPG         
Sbjct: 445 NRGFPGQDGLAGPKGA---PGERGPSGLAGPKGANGDPGRPGE---PGLPGARGLTGRPG 498

Query: 520 -AGPLG 524
            AGP G
Sbjct: 499 DAGPQG 504



 Score = 38.1 bits (87), Expect = 0.023
 Identities = 42/133 (31%), Positives = 46/133 (34%), Gaps = 29/133 (21%)

Query: 414 APTARGLEGRQVVP--PPPPAPRPGPVLGAPGELALAGAAAAYPGKG------------- 458
           AP  RG +G    P  P PP P PGP    PG   L G  AA    G             
Sbjct: 76  APGPRGRDGEPGTPGNPGPPGP-PGP----PGPPGLGGNFAAQMAGGFDEKAGGAQLGVM 130

Query: 459 ------AAPYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALP 512
                   P  PP P  +    P      PGE G  G++ P       GPPG    D   
Sbjct: 131 QGPMGPMGPRGPPGP--AGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEA 188

Query: 513 G-PYAAAAAGPLG 524
           G P  A   GP G
Sbjct: 189 GKPGKAGERGPPG 201



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 42/136 (30%), Positives = 48/136 (35%), Gaps = 30/136 (22%)

Query: 414 APTARGLEGRQ--------VVPPPPPAPRPGPV-LGAPGELALAGAAAAYPGKGAAPYAP 464
           AP   G EG++        V P  PP  R  P   G PG+  LAG   A   +G +  A 
Sbjct: 412 APGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAG 471

Query: 465 PA--------PSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYA 516
           P         P    L     L   PG+AG  G   P  A    G PG       PGP  
Sbjct: 472 PKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGP------PGPQG 525

Query: 517 AAA-------AGPLGA 525
           A          GP GA
Sbjct: 526 ARGQPGVMGFPGPKGA 541



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 38/117 (32%), Positives = 41/117 (35%), Gaps = 11/117 (9%)

Query: 414 APTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALA 473
           AP  RGL G+        A  PGP  G  GE    GA    PG       P  P      
Sbjct: 556 APGLRGLPGKD--GETGAAGPPGPA-GPAGERGEQGA----PGPSGFQGLPGPPGPPGEG 608

Query: 474 HPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAA----GPLGAA 526
                  +PGEAGA GL  P     F G  G      L GP          GP GA+
Sbjct: 609 GKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGAS 665



 Score = 37.0 bits (84), Expect = 0.051
 Identities = 36/114 (31%), Positives = 42/114 (36%), Gaps = 14/114 (12%)

Query: 417 ARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKG----AAPYAPPAPSRSAL 472
           A G++G    P    +P P    G PGE    G A A   +G      P  PP P     
Sbjct: 235 APGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGP----- 289

Query: 473 AHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAA 526
             P      PG  GA G A P  A    GP G       PG     + GP GA+
Sbjct: 290 VGPAGGPGFPGAPGAKGEAGPTGAR---GPEGAQGPRGEPG--TPGSPGPAGAS 338



 Score = 37.0 bits (84), Expect = 0.051
 Identities = 113/446 (25%), Positives = 143/446 (32%), Gaps = 90/446 (20%)

Query: 140  GASGWGGGWGRR--LGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRA------PSSSF 191
            GA+G  G  G R  +G  G     G   GR   G + PPG   +   +       P+ S 
Sbjct: 687  GAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSA 746

Query: 192  VLRGSPAPRADGG--GEVTFPEVATCEVVDLGIGPQARAFSVPLGASLQGWGTAAGPSPE 249
              RG+P  R + G  G   F      +      G Q  A       +    G +  P P+
Sbjct: 747  GARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQ 806

Query: 250  LGSGQGWLPFYPFSTADPSAEDLHMASGPWHHPGHIFCQEEAWTENLNFTPDGRANGLPR 309
              +G         +   P A     A+G    PG           N N  P G     P 
Sbjct: 807  GPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPG----------SNGNPGPPGP----PG 852

Query: 310  ALNQGLQRTRQGKAGKSQLLPSKARKCQRQGAWGPEESDQCLELGQYLDQEVEATR---- 365
               +   +  +G +G     P +A +   QG  GP       E G+  D           
Sbjct: 853  PSGKDGPKGARGDSGP----PGRAGEPGLQGPAGPPG-----EKGEPGDDGPSGAEGPPG 903

Query: 366  -TGLAKAGSDMGSTGDWHSRIKKRMYGEMAEVFWRVNGDFATHCGDFEKAPTARGLEGRQ 424
              GLA     +G  G    R    + G   E                + AP A G  G  
Sbjct: 904  PQGLAGQRGIVGLPGQRGERGFPGLPGPSGEP-------------GKQGAPGASGDRGPP 950

Query: 425  VVPPPP----PAPRPGPV--LGAPGELALAGAAAAYPGKG-----AAPYAPPAPSRSALA 473
                PP    PA  PG     GA G     GAA     +G      AP AP  P     A
Sbjct: 951  GPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPA 1010

Query: 474  HPISLMTLPGEAGAAG-LAPPGHAAAFG--GPPG--------------GLL-------LD 509
             P       GEAGA G + P G A A G  GP G              GL        L 
Sbjct: 1011 GPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQ 1070

Query: 510  ALPGPYAAA----AAGPLGAAPDRFP 531
             LPGP   +    A+GP G +  R P
Sbjct: 1071 GLPGPPGPSGDQGASGPAGPSGPRGP 1096



 Score = 36.6 bits (83), Expect = 0.066
 Identities = 34/115 (29%), Positives = 40/115 (34%), Gaps = 3/115 (2%)

Query: 415 PTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAH 474
           P   G  G +  P PP  P      G PG+    G       +G  P  P  P       
Sbjct: 164 PGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGF-PGTPGLPGVKGHRG 222

Query: 475 PISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLGAAPDR 529
              L    GEAGA G+     +    G PG +    LPG       GP GAA  R
Sbjct: 223 YPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPG--ERGRTGPAGAAGAR 275



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 47/155 (30%), Positives = 55/155 (35%), Gaps = 41/155 (26%)

Query: 415 PTARGLEGR--------QVVP---------PPPPAPR-----------PGPV-----LGA 441
           P ARGL GR        +V P         P PP P+           PGP       G 
Sbjct: 488 PGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGK 547

Query: 442 PGELALAGAAA--AYPGKGAAPYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAF 499
            GE  L GA      PGK     A   P  +  A        PG +G  GL  P      
Sbjct: 548 AGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGE 607

Query: 500 GGPPGGLLLDALPGPYAAAAAGPLGAAPDR-FPAD 533
           GG PG      +PG   A A G +G   +R FP +
Sbjct: 608 GGKPGD---QGVPG--EAGAPGLVGPRGERGFPGE 637



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 28/79 (35%), Positives = 31/79 (39%), Gaps = 9/79 (11%)

Query: 428 PPPPAPRPGP--VLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEA 485
           PP PA  PGP    G PGE    G +     +G  P  P  P     A        PG+A
Sbjct: 142 PPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGP-PGPPGKPGDDGEAGK------PGKA 194

Query: 486 GAAGLAPPGHAAAFGGPPG 504
           G  G   P  A  F G PG
Sbjct: 195 GERGPPGPQGARGFPGTPG 213



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 45/132 (34%), Positives = 50/132 (37%), Gaps = 28/132 (21%)

Query: 417 ARGLEGRQVVPPP--PPAPR--PGPV--LGAPGELALAGAAAAYPGKG----AAPYAPPA 466
           A G+ G    P P  PP P+   GP+   G  GE  +AG       KG    A P   P 
Sbjct: 355 APGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPG 414

Query: 467 PSRSALAHPISLMTLPGEAGAAG-LAPPGHAAAFG--GPPGGLLLDALPGPYAA------ 517
           P     A         GE G  G + PPG   A G  G PG    D L GP  A      
Sbjct: 415 P-----AGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPG---QDGLAGPKGAPGERGP 466

Query: 518 -AAAGPLGAAPD 528
              AGP GA  D
Sbjct: 467 SGLAGPKGANGD 478



 Score = 33.5 bits (75), Expect = 0.56
 Identities = 36/116 (31%), Positives = 42/116 (36%), Gaps = 19/116 (16%)

Query: 418  RGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPI- 476
            RG  G Q +P PP         G  G+   +G A   P     P  P  PS    A+ I 
Sbjct: 1064 RGFTGLQGLPGPP---------GPSGDQGASGPAG--PSGPRGPPGPVGPSGKDGANGIP 1112

Query: 477  SLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGP----YAAAAAGPLGAAPD 528
              +  PG  G +G   P       GPPG       PGP     A A  GP    PD
Sbjct: 1113 GPIGPPGPRGRSGETGPAGPPGNPGPPGP---PGPPGPGIDMSAFAGLGPREKGPD 1165


>gi|160707881 formin 2 [Homo sapiens]
          Length = 1722

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 53/179 (29%), Positives = 65/179 (36%), Gaps = 42/179 (23%)

Query: 415  PTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAH 474
            P    L+G +++PPPPP P PG  +  P  L  AG     P  GA    PP    +A+  
Sbjct: 897  PQPPPLQGTEMLPPPPP-PLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPP 955

Query: 475  PISL----MTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDA-LPGPYAAAAAG-----PLG 524
            P  L    + LP     AG+ PP      G PP   L  A +P P     AG     PL 
Sbjct: 956  PPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP 1015

Query: 525  AAPDRFPADLDLDMFSGSLECDVESIILNDFMDSDEMDFNFDSALPPPPP-GLAGAPPP 582
             A    P  L                                + +PPPPP   AG PPP
Sbjct: 1016 GAGIPPPPPLP------------------------------GAGIPPPPPLPGAGIPPP 1044



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 49/162 (30%), Positives = 54/162 (33%), Gaps = 46/162 (28%)

Query: 429  PPPAPRPGPVLGAPGELALAGAAAAYPGKGAA-PYAPPAPSRSALAHPISLMTLPGEAGA 487
            PPP P PG  +  P  L  AG     P  GA  P  PP P       P     LPG    
Sbjct: 976  PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP----PLPG---- 1027

Query: 488  AGLAPPGHAAAFGGPPGGLLLDA-LPGPYAAAAAG-----PLGAAPDRFPADLDLDMFSG 541
            AG+ PP      G PP   L  A +P P     AG     PL  A    P  L       
Sbjct: 1028 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLP------ 1081

Query: 542  SLECDVESIILNDFMDSDEMDFNFDSALPPPPP-GLAGAPPP 582
                                     + +PPPPP   AG PPP
Sbjct: 1082 ------------------------GAGIPPPPPLPGAGIPPP 1099



 Score = 36.6 bits (83), Expect = 0.066
 Identities = 35/98 (35%), Positives = 39/98 (39%), Gaps = 12/98 (12%)

Query: 426  VPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAA-PYAPPAPSRSALAHPISLMTLPGE 484
            +PPPPP P  G  +  P  L  AG     P  GA  P  PP P       P     LPG 
Sbjct: 1008 IPPPPPLPGAG--IPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP----PLPG- 1060

Query: 485  AGAAGLAPPGHAAAFGGPPGGLLLDA-LPGPYAAAAAG 521
               AG+ PP      G PP   L  A +P P     AG
Sbjct: 1061 ---AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1095



 Score = 36.6 bits (83), Expect = 0.066
 Identities = 33/98 (33%), Positives = 36/98 (36%), Gaps = 17/98 (17%)

Query: 415  PTARGLEGRQVVPPPP--------PAPRPGPVLGAPGELALAGAAAAYPGKGAA-PYAPP 465
            P    L G  + PPPP        P P PG  +  P  L  AG     P  GA  P  PP
Sbjct: 1009 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1068

Query: 466  APSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPP 503
             P       P     LPG    AG+ PP      G PP
Sbjct: 1069 LPGAGIPPPP----PLPG----AGIPPPPPLPGAGIPP 1098



 Score = 36.6 bits (83), Expect = 0.066
 Identities = 32/97 (32%), Positives = 36/97 (37%), Gaps = 15/97 (15%)

Query: 415  PTARGLEGRQVVPPPP--------PAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPA 466
            P    L G  + PPPP        P P PG  +  P  L  AG     P  GA    PP 
Sbjct: 1086 PPPPPLPGAGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1145

Query: 467  PSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPP 503
              R  +  P     LPG    AG+ PP      G PP
Sbjct: 1146 LPRVGIPPP---PPLPG----AGIPPPPPLPGAGIPP 1175



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 33/98 (33%), Positives = 36/98 (36%), Gaps = 17/98 (17%)

Query: 415  PTARGLEGRQVVPPPP--------PAPRPGPVLGAPGELALAGAAAAYPGKGAA-PYAPP 465
            P    L G  + PPPP        P P PG  +  P  L  AG     P  GA  P  PP
Sbjct: 1042 PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPP 1101

Query: 466  APSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPP 503
             P       P     LPG    AG+ PP      G PP
Sbjct: 1102 LPGVGIPPPP----PLPG----AGIPPPPPLPGAGIPP 1131



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 35/108 (32%), Positives = 38/108 (35%), Gaps = 20/108 (18%)

Query: 426  VPPPPPAPR---------PGPVLGAPGELALAGAAAAYPGKGAA-PYAPPAPSRSALAHP 475
            +PPPPP PR         PG  +  P  L  AG     P  G   P  PP P       P
Sbjct: 1140 IPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPP 1199

Query: 476  ISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPL 523
                 LPG    AG+ PP      G PP       LP P       PL
Sbjct: 1200 ----PLPG----AGIPPPPPLPGMGIPPAP--APPLPPPGTGIPPPPL 1237



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 51/183 (27%), Positives = 58/183 (31%), Gaps = 64/183 (34%)

Query: 416  TARGLEGRQVVPPPPPAPRPG------PVLGAPGELALAGA------AAAYPGKGAAPYA 463
            ++  + G  +VPPPPP P PG      P    P    L G           PG G  P  
Sbjct: 866  SSSSMPGLGMVPPPPP-PLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPLPGAGIPP-P 923

Query: 464  PPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDA---LPGPYAAAAA 520
            PP P    L  P     LPG    AG+ PP        PP   L  A   LP P   A  
Sbjct: 924  PPLPGAGILPLP----PLPG----AGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPGAGI 975

Query: 521  GPLGAAPDRFPADLDLDMFSGSLECDVESIILNDFMDSDEMDFNFDSALPPPPP-GLAGA 579
             P    P   P                                   + +PPPPP   AG 
Sbjct: 976  PP----PPPLPG----------------------------------AGIPPPPPLPGAGI 997

Query: 580  PPP 582
            PPP
Sbjct: 998  PPP 1000



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 27/91 (29%), Positives = 32/91 (35%), Gaps = 10/91 (10%)

Query: 415 PTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAH 474
           P +   E R+  P  PP+P   PV  AP   A   AA   P   A P+    P   A   
Sbjct: 280 PESLAAEPRE--PQQPPSPGGLPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGPGEEAAGA 337

Query: 475 PISLMTLPGEAGAAGLAPPGHAAAFGGPPGG 505
           P+         GA      G   AF   P G
Sbjct: 338 PV--------RGAGDTDEEGEEDAFEDAPRG 360



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 32/105 (30%), Positives = 39/105 (37%), Gaps = 17/105 (16%)

Query: 415  PTARGLEGRQVVPPPP--------PAPRPGPVLGAPGELALAG--AAAAYPGKGAAPY-A 463
            P    L G  + PPPP        P P PG  +  P  L  AG       PG G  P  A
Sbjct: 1163 PPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPA 1222

Query: 464  PPAPSRSALAHPISLMTLPG-----EAGAAGLAPPGHAAAFGGPP 503
            PP P       P  L+ + G     + G++ L  P     F  PP
Sbjct: 1223 PPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTP-QVCGFLPPP 1266


>gi|155030232 proline, glutamic acid and leucine rich protein 1
           [Homo sapiens]
          Length = 1130

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 50/175 (28%), Positives = 66/175 (37%), Gaps = 33/175 (18%)

Query: 425 VVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGE 484
           V PP  P+P   P    PG +   G   + P  G  P A P PS   +  P +    P  
Sbjct: 651 VPPPEAPSPFRAPPFHPPGPMPSVG---SMPSAGPMPSAGPMPSAGPV--PSARPGPPTT 705

Query: 485 AGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAA-------GPLGAAPDRFPADLDLD 537
           A   GL+ PG  +    PP       LPGP    A         P G  P   P D   +
Sbjct: 706 ANHLGLSVPGLVSV---PP-----RLLPGPENHRAGSNEDPILAPSGTPPPTIPPD---E 754

Query: 538 MFSGSL---------ECDVESIILNDFMDSDEMDFNFDSALPP-PPPGLAGAPPP 582
            F G +         + +   + ++   DSD+        LPP PPP  +GA PP
Sbjct: 755 TFGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPP 809



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 53/175 (30%), Positives = 64/175 (36%), Gaps = 37/175 (21%)

Query: 428 PPPPAPRP--GPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEA 485
           PPP AP P   P    PG +   G+    P  G  P A P PS   +  P +    P  A
Sbjct: 652 PPPEAPSPFRAPPFHPPGPMPSVGSM---PSAGPMPSAGPMPSAGPV--PSARPGPPTTA 706

Query: 486 GAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAG-------PLGAAPDRFPADLDLDM 538
              GL+ PG  +    PP       LPGP    A         P G  P   P D   + 
Sbjct: 707 NHLGLSVPGLVSV---PPR-----LLPGPENHRAGSNEDPILAPSGTPPPTIPPD---ET 755

Query: 539 FSGSLE------------CDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPP 581
           F G +              DVE  + +D  DS  +       LPPPPP  A  PP
Sbjct: 756 FGGRVPRPAFVHYDKEEASDVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPP 810



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 17/35 (48%), Positives = 18/35 (51%), Gaps = 4/35 (11%)

Query: 427 PPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAP 461
           PPPPP P PGPV   P +L   G     PG G  P
Sbjct: 842 PPPPPPPVPGPVTLPPPQLVPEGT----PGGGGPP 872


>gi|24497506 forkhead box A3 [Homo sapiens]
          Length = 350

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 39/118 (33%), Positives = 49/118 (41%), Gaps = 17/118 (14%)

Query: 16  FAPQSRPRSCTWPLPQPDLAGDEDGAL------GAGVAEGAEDCGPERRATAPAMAPAPP 69
           + P   P S   PLP   LA     A       G GV+ G+   G              P
Sbjct: 50  YPPGGLPAS---PLPSGPLAPPAPAAPLGPTFPGLGVSGGSSSSGYGAPGPGLVHGKEMP 106

Query: 70  LGAEVGPLRKAKSSRRNAWGNLSYADLITKAIESAPDKRLTLSQIYDWMVRYVPYFKD 127
            G    PL  AK          SY  LIT AI+ AP K LTLS+IY W++   PY+++
Sbjct: 107 KGYR-RPLAHAKPP-------YSYISLITMAIQQAPGKMLTLSEIYQWIMDLFPYYRE 156


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 45/124 (36%), Positives = 51/124 (41%), Gaps = 14/124 (11%)

Query: 415  PTARGLEGRQVVPPPPP-APRPGP--VLGAPGELALAGAAAAYPGK--GAAPYAPPAPSR 469
            P A G EG +  P P   + + GP  + G PGE  L GA  A PG   G  P  PP P  
Sbjct: 1011 PGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA-PGLKGGEGPQGPPGPVG 1069

Query: 470  S-------ALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYA-AAAAG 521
            S         A PI L   PG  G  G A    A    GP G    D + GP      AG
Sbjct: 1070 SPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAG 1129

Query: 522  PLGA 525
            P G+
Sbjct: 1130 PAGS 1133



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 41/132 (31%), Positives = 48/132 (36%), Gaps = 25/132 (18%)

Query: 412  EKAPTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGA----APYAPPAP 467
            EK P  +G  GR  V  P   P P    G+PGE    G       KG+        PP P
Sbjct: 1106 EKGP--QGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGP 1163

Query: 468  SRSALAHPISLMTLPGEAGAAGLAPPGHAAAFG-----------GPPGGLLLDALPGPYA 516
                L  P+    + G  G  G  P G    FG           GPPG + L  LPGP  
Sbjct: 1164 P--GLQGPVGAPGIAGGDGEPG--PRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1219

Query: 517  AAA----AGPLG 524
                    GP+G
Sbjct: 1220 EKGENGDVGPMG 1231



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 40/112 (35%), Positives = 44/112 (39%), Gaps = 19/112 (16%)

Query: 425  VVPPPPPAPRPGPV--------LGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPI 476
            VV P  P    GP+         G PGE  L GAA    GK  A   P     S    P 
Sbjct: 980  VVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA----GKEGAKGDPGPQGISGKDGPA 1035

Query: 477  SLMTLPGEAGAAGL-APPGHAAAFG--GPPGGLLLDALPGPY-AAAAAGPLG 524
             L   PGE G  G    PG     G  GPPG +     PG   +A  AGP+G
Sbjct: 1036 GLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPV---GSPGERGSAGTAGPIG 1084



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 38/119 (31%), Positives = 42/119 (35%), Gaps = 27/119 (22%)

Query: 418 RGLEGRQVVPPPPPAPRPGPV--------LGAPGELALAG-----AAAAYPG-KG----A 459
           RG++G     PP P  +PG           G PGE    G          PG KG     
Sbjct: 576 RGVQG-----PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGER 630

Query: 460 APYAPPAP----SRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGP 514
            P  PP P            I    LPGEAG  GL  P       G PG   +D  PGP
Sbjct: 631 GPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGP 689



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 50/173 (28%), Positives = 61/173 (35%), Gaps = 40/173 (23%)

Query: 427 PPPPPAPRPGPVLGAPGELALAGAA----AAYPGKGAAPYAPPAPSRSALAHPISLMT-L 481
           P  PP    GP  G P E  +   +     AY  KG            A+  P  L+   
Sbjct: 405 PTSPPNEEFGP--GVPAETDITETSINGHGAYGEKGQK-------GEPAVVEPGMLVEGP 455

Query: 482 PGEAGAAG-LAPPGHAAAFG--------GPPG--GLL-LDALPGPYAAAAAGPLGAAPDR 529
           PG AG AG + PPG     G        GPPG  GL   D LPGP      G +   P R
Sbjct: 456 PGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGP-----PGTMLMLPFR 510

Query: 530 FPADLDLDMFSGSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPP 582
           +  D        + E   ++I+                  PP P GL G P P
Sbjct: 511 YGGDGSKGPTISAQEAQAQAIL---------QQARIALRGPPGPMGLTGRPGP 554



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 51/170 (30%), Positives = 57/170 (33%), Gaps = 64/170 (37%)

Query: 415  PTARGLEGRQ-------------------VVPPPPPAPRPGP-----VLGAPGELALAGA 450
            P A G EGRQ                    V P  PA +PGP     + G  GE  L GA
Sbjct: 1377 PGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGA 1436

Query: 451  AAAYPGKGAAPYAPPA--------PSRSALAHP--ISLMT------------LPGEAGAA 488
            A      G  P  PP          S+    HP  I L+             LPG  G+ 
Sbjct: 1437 AGQDGPPG--PMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSP 1494

Query: 489  GL----APPGHAAAFG--GPPGGLLLDALPGPYA----AAAAGPLGAAPD 528
            G       PG A   G  GPPG      LPGP        + GP G   D
Sbjct: 1495 GAKGDGGIPGPAGPLGPPGPPG------LPGPQGPKGNKGSTGPAGQKGD 1538



 Score = 33.1 bits (74), Expect = 0.73
 Identities = 35/121 (28%), Positives = 38/121 (31%), Gaps = 22/121 (18%)

Query: 418 RGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPIS 477
           RGL G +  P  P  P    V G PG     G      G+   P     P    L  P  
Sbjct: 663 RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQ----GEPGPPGQQGNPGPQGLPGPQG 718

Query: 478 LMTLPGEAGAAGL----------APPGHAAAFG--------GPPGGLLLDALPGPYAAAA 519
            +  PGE G  G            PPGH    G        GPPG       PGP     
Sbjct: 719 PIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKG 778

Query: 520 A 520
           A
Sbjct: 779 A 779



 Score = 33.1 bits (74), Expect = 0.73
 Identities = 51/177 (28%), Positives = 57/177 (32%), Gaps = 44/177 (24%)

Query: 427  PPPPPAPR-PGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEA 485
            PP PP PR P    GA G     G+  +  G G                        GE 
Sbjct: 1232 PPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK----------------------GEP 1269

Query: 486  GAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAA----AAGPLG-------AAPDRFPADL 534
            G AG   P   A  GGP G        GP  AA    A GP G         P  FP D 
Sbjct: 1270 GEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDP 1329

Query: 535  DLDMFSGSLECDVESIILNDFMDSDE-MDFNFDSALPPPPPGLAGAP-PPNQSWVPG 589
                  G            D +  D+  D +     PP P G AG P PP +   PG
Sbjct: 1330 GPPGEPGPAG--------QDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPG 1378



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 106/414 (25%), Positives = 134/414 (32%), Gaps = 80/414 (19%)

Query: 138 KVGASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRAPSSSFVLRGSP 197
           K G  G  G  G R G+PG     G +  R  +G    PG       R P      +G P
Sbjct: 587 KPGKRGRPGADGGR-GMPGEP---GAKGDRGFDGLPGLPGDKGHRGERGP------QGPP 636

Query: 198 APRADGG-----GEVTFPEVATCEVVDLGI-GPQARAFSVPLGASLQGWGTAAGPSPELG 251
            P  D G     GE+  P     E    G+ GP+      P    + G     GP   +G
Sbjct: 637 GPPGDDGMRGEDGEIG-PRGLPGEAGPRGLLGPRGTP-GAPGQPGMAGVDGPPGPKGNMG 694

Query: 252 SGQGWLPFYPFSTADPSAEDLHMASGPWHHPGHIFCQEEAWTENLNFTPDGRAN--GLPR 309
             QG  P  P    +P  + L    GP   PG                P G+    GLP 
Sbjct: 695 P-QGE-PGPPGQQGNPGPQGLPGPQGPIGPPGEK-------------GPQGKPGLAGLPG 739

Query: 310 ALNQGLQRTRQGKAGKSQLL--PSKARKCQRQGAWGPEESDQCLELGQYLDQEVEATRTG 367
           A        ++G++G+   L  P         G  G + +D    L      + E    G
Sbjct: 740 ADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLK---GSKGEKGEDG 796

Query: 368 LAKAGSDMGSTGDWHSRIKKRMYGEMAEVFWRVNGDFATHCGDFEKAPTA-------RGL 420
                 DMG  GD          GE+ ++  R  G+           PT         G 
Sbjct: 797 FPGFKGDMGLKGD---------RGEVGQIGPR--GEDGPEGPKGRAGPTGDPGPSGQAGE 845

Query: 421 EGRQVVPPPPPAP-RPGP--------VLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSA 471
           +G+  VP  P  P R GP          GA GE    G A     +G      P  SR A
Sbjct: 846 KGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGA 905

Query: 472 LAHPISLMTLPGEAGAAGL-APPGHAAAFG-----------GPPGGLLLDALPG 513
              P       G +G  G   PPG     G           GPPG    D LPG
Sbjct: 906 RG-PTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPG 958



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 26/78 (33%), Positives = 31/78 (39%), Gaps = 2/78 (2%)

Query: 128  KGDSNSSA-GWKVGASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRA 186
            KGD        K G +G  G  G R GLPGA    GL+ G   +G   P G      S  
Sbjct: 1020 KGDPGPQGISGKDGPAGLRGFPGER-GLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAG 1078

Query: 187  PSSSFVLRGSPAPRADGG 204
             +    L G P P+   G
Sbjct: 1079 TAGPIGLPGRPGPQGPPG 1096



 Score = 30.4 bits (67), Expect = 4.8
 Identities = 43/166 (25%), Positives = 55/166 (33%), Gaps = 24/166 (14%)

Query: 415  PTARGLEGRQVVPPPPPAPRPGPVL----------GAPGELALAGAAAAYPGKG-----A 459
            P A G +G    PP P  P   P L          G PG + L G       KG      
Sbjct: 1434 PGAAGQDG----PPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1489

Query: 460  APYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAA 519
               +P A     +  P   +  PG  G  G   P       GP G      LPGP    +
Sbjct: 1490 TQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP--PGS 1547

Query: 520  AGPLGAAPDRFP--ADLDLDMFSGSLECDVESIILNDFMDSDEMDF 563
             GP G      P  +       +  ++ D +  IL D+ D  E  F
Sbjct: 1548 PGPPGEVIQPLPILSSKKTRRHTEGMQADADDNIL-DYSDGMEEIF 1592



 Score = 30.0 bits (66), Expect = 6.2
 Identities = 32/107 (29%), Positives = 37/107 (34%), Gaps = 6/107 (5%)

Query: 418  RGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPIS 477
            +G  G +    PP A  P    G PG+    G     PG    P  P  P     A    
Sbjct: 1287 KGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN----PGPVGFPGDPGPPGEPGPAGQDG 1342

Query: 478  LMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLG 524
            +    GE G  G   P   +   GPPG       PG  AA A G  G
Sbjct: 1343 VGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPG--AAGAEGRQG 1387


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 45/124 (36%), Positives = 51/124 (41%), Gaps = 14/124 (11%)

Query: 415  PTARGLEGRQVVPPPPP-APRPGP--VLGAPGELALAGAAAAYPGK--GAAPYAPPAPSR 469
            P A G EG +  P P   + + GP  + G PGE  L GA  A PG   G  P  PP P  
Sbjct: 960  PGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA-PGLKGGEGPQGPPGPVG 1018

Query: 470  S-------ALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYA-AAAAG 521
            S         A PI L   PG  G  G A    A    GP G    D + GP      AG
Sbjct: 1019 SPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAG 1078

Query: 522  PLGA 525
            P G+
Sbjct: 1079 PAGS 1082



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 41/132 (31%), Positives = 48/132 (36%), Gaps = 25/132 (18%)

Query: 412  EKAPTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGA----APYAPPAP 467
            EK P  +G  GR  V  P   P P    G+PGE    G       KG+        PP P
Sbjct: 1055 EKGP--QGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGP 1112

Query: 468  SRSALAHPISLMTLPGEAGAAGLAPPGHAAAFG-----------GPPGGLLLDALPGPYA 516
                L  P+    + G  G  G  P G    FG           GPPG + L  LPGP  
Sbjct: 1113 P--GLQGPVGAPGIAGGDGEPG--PRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1168

Query: 517  AAA----AGPLG 524
                    GP+G
Sbjct: 1169 EKGENGDVGPMG 1180



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 40/112 (35%), Positives = 44/112 (39%), Gaps = 19/112 (16%)

Query: 425  VVPPPPPAPRPGPV--------LGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPI 476
            VV P  P    GP+         G PGE  L GAA    GK  A   P     S    P 
Sbjct: 929  VVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA----GKEGAKGDPGPQGISGKDGPA 984

Query: 477  SLMTLPGEAGAAGL-APPGHAAAFG--GPPGGLLLDALPGPY-AAAAAGPLG 524
             L   PGE G  G    PG     G  GPPG +     PG   +A  AGP+G
Sbjct: 985  GLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPV---GSPGERGSAGTAGPIG 1033



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 38/119 (31%), Positives = 42/119 (35%), Gaps = 27/119 (22%)

Query: 418 RGLEGRQVVPPPPPAPRPGPV--------LGAPGELALAG-----AAAAYPG-KG----A 459
           RG++G     PP P  +PG           G PGE    G          PG KG     
Sbjct: 525 RGVQG-----PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGER 579

Query: 460 APYAPPAP----SRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGP 514
            P  PP P            I    LPGEAG  GL  P       G PG   +D  PGP
Sbjct: 580 GPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGP 638



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 50/173 (28%), Positives = 61/173 (35%), Gaps = 40/173 (23%)

Query: 427 PPPPPAPRPGPVLGAPGELALAGAA----AAYPGKGAAPYAPPAPSRSALAHPISLMT-L 481
           P  PP    GP  G P E  +   +     AY  KG            A+  P  L+   
Sbjct: 354 PTSPPNEEFGP--GVPAETDITETSINGHGAYGEKGQK-------GEPAVVEPGMLVEGP 404

Query: 482 PGEAGAAG-LAPPGHAAAFG--------GPPG--GLL-LDALPGPYAAAAAGPLGAAPDR 529
           PG AG AG + PPG     G        GPPG  GL   D LPGP      G +   P R
Sbjct: 405 PGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGP-----PGTMLMLPFR 459

Query: 530 FPADLDLDMFSGSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPP 582
           +  D        + E   ++I+                  PP P GL G P P
Sbjct: 460 YGGDGSKGPTISAQEAQAQAIL---------QQARIALRGPPGPMGLTGRPGP 503



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 51/170 (30%), Positives = 57/170 (33%), Gaps = 64/170 (37%)

Query: 415  PTARGLEGRQ-------------------VVPPPPPAPRPGP-----VLGAPGELALAGA 450
            P A G EGRQ                    V P  PA +PGP     + G  GE  L GA
Sbjct: 1326 PGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGA 1385

Query: 451  AAAYPGKGAAPYAPPA--------PSRSALAHP--ISLMT------------LPGEAGAA 488
            A      G  P  PP          S+    HP  I L+             LPG  G+ 
Sbjct: 1386 AGQDGPPG--PMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSP 1443

Query: 489  GL----APPGHAAAFG--GPPGGLLLDALPGPYA----AAAAGPLGAAPD 528
            G       PG A   G  GPPG      LPGP        + GP G   D
Sbjct: 1444 GAKGDGGIPGPAGPLGPPGPPG------LPGPQGPKGNKGSTGPAGQKGD 1487



 Score = 33.1 bits (74), Expect = 0.73
 Identities = 35/121 (28%), Positives = 38/121 (31%), Gaps = 22/121 (18%)

Query: 418 RGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPIS 477
           RGL G +  P  P  P    V G PG     G      G+   P     P    L  P  
Sbjct: 612 RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQ----GEPGPPGQQGNPGPQGLPGPQG 667

Query: 478 LMTLPGEAGAAGL----------APPGHAAAFG--------GPPGGLLLDALPGPYAAAA 519
            +  PGE G  G            PPGH    G        GPPG       PGP     
Sbjct: 668 PIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKG 727

Query: 520 A 520
           A
Sbjct: 728 A 728



 Score = 33.1 bits (74), Expect = 0.73
 Identities = 51/177 (28%), Positives = 57/177 (32%), Gaps = 44/177 (24%)

Query: 427  PPPPPAPR-PGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEA 485
            PP PP PR P    GA G     G+  +  G G                        GE 
Sbjct: 1181 PPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK----------------------GEP 1218

Query: 486  GAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAA----AAGPLG-------AAPDRFPADL 534
            G AG   P   A  GGP G        GP  AA    A GP G         P  FP D 
Sbjct: 1219 GEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDP 1278

Query: 535  DLDMFSGSLECDVESIILNDFMDSDE-MDFNFDSALPPPPPGLAGAP-PPNQSWVPG 589
                  G            D +  D+  D +     PP P G AG P PP +   PG
Sbjct: 1279 GPPGEPGPAG--------QDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPG 1327



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 106/414 (25%), Positives = 134/414 (32%), Gaps = 80/414 (19%)

Query: 138 KVGASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRAPSSSFVLRGSP 197
           K G  G  G  G R G+PG     G +  R  +G    PG       R P      +G P
Sbjct: 536 KPGKRGRPGADGGR-GMPGEP---GAKGDRGFDGLPGLPGDKGHRGERGP------QGPP 585

Query: 198 APRADGG-----GEVTFPEVATCEVVDLGI-GPQARAFSVPLGASLQGWGTAAGPSPELG 251
            P  D G     GE+  P     E    G+ GP+      P    + G     GP   +G
Sbjct: 586 GPPGDDGMRGEDGEIG-PRGLPGEAGPRGLLGPRGTP-GAPGQPGMAGVDGPPGPKGNMG 643

Query: 252 SGQGWLPFYPFSTADPSAEDLHMASGPWHHPGHIFCQEEAWTENLNFTPDGRAN--GLPR 309
             QG  P  P    +P  + L    GP   PG                P G+    GLP 
Sbjct: 644 P-QGE-PGPPGQQGNPGPQGLPGPQGPIGPPGEK-------------GPQGKPGLAGLPG 688

Query: 310 ALNQGLQRTRQGKAGKSQLL--PSKARKCQRQGAWGPEESDQCLELGQYLDQEVEATRTG 367
           A        ++G++G+   L  P         G  G + +D    L      + E    G
Sbjct: 689 ADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLK---GSKGEKGEDG 745

Query: 368 LAKAGSDMGSTGDWHSRIKKRMYGEMAEVFWRVNGDFATHCGDFEKAPTA-------RGL 420
                 DMG  GD          GE+ ++  R  G+           PT         G 
Sbjct: 746 FPGFKGDMGLKGD---------RGEVGQIGPR--GEDGPEGPKGRAGPTGDPGPSGQAGE 794

Query: 421 EGRQVVPPPPPAP-RPGP--------VLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSA 471
           +G+  VP  P  P R GP          GA GE    G A     +G      P  SR A
Sbjct: 795 KGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGA 854

Query: 472 LAHPISLMTLPGEAGAAGL-APPGHAAAFG-----------GPPGGLLLDALPG 513
              P       G +G  G   PPG     G           GPPG    D LPG
Sbjct: 855 RG-PTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPG 907



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 26/78 (33%), Positives = 31/78 (39%), Gaps = 2/78 (2%)

Query: 128  KGDSNSSA-GWKVGASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRA 186
            KGD        K G +G  G  G R GLPGA    GL+ G   +G   P G      S  
Sbjct: 969  KGDPGPQGISGKDGPAGLRGFPGER-GLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAG 1027

Query: 187  PSSSFVLRGSPAPRADGG 204
             +    L G P P+   G
Sbjct: 1028 TAGPIGLPGRPGPQGPPG 1045



 Score = 30.4 bits (67), Expect = 4.8
 Identities = 43/166 (25%), Positives = 55/166 (33%), Gaps = 24/166 (14%)

Query: 415  PTARGLEGRQVVPPPPPAPRPGPVL----------GAPGELALAGAAAAYPGKG-----A 459
            P A G +G    PP P  P   P L          G PG + L G       KG      
Sbjct: 1383 PGAAGQDG----PPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1438

Query: 460  APYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAA 519
               +P A     +  P   +  PG  G  G   P       GP G      LPGP    +
Sbjct: 1439 TQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP--PGS 1496

Query: 520  AGPLGAAPDRFP--ADLDLDMFSGSLECDVESIILNDFMDSDEMDF 563
             GP G      P  +       +  ++ D +  IL D+ D  E  F
Sbjct: 1497 PGPPGEVIQPLPILSSKKTRRHTEGMQADADDNIL-DYSDGMEEIF 1541



 Score = 30.0 bits (66), Expect = 6.2
 Identities = 32/107 (29%), Positives = 37/107 (34%), Gaps = 6/107 (5%)

Query: 418  RGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPIS 477
            +G  G +    PP A  P    G PG+    G     PG    P  P  P     A    
Sbjct: 1236 KGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN----PGPVGFPGDPGPPGEPGPAGQDG 1291

Query: 478  LMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLG 524
            +    GE G  G   P   +   GPPG       PG  AA A G  G
Sbjct: 1292 VGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPG--AAGAEGRQG 1336


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 45/124 (36%), Positives = 51/124 (41%), Gaps = 14/124 (11%)

Query: 415  PTARGLEGRQVVPPPPP-APRPGP--VLGAPGELALAGAAAAYPGK--GAAPYAPPAPSR 469
            P A G EG +  P P   + + GP  + G PGE  L GA  A PG   G  P  PP P  
Sbjct: 999  PGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGA-PGLKGGEGPQGPPGPVG 1057

Query: 470  S-------ALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYA-AAAAG 521
            S         A PI L   PG  G  G A    A    GP G    D + GP      AG
Sbjct: 1058 SPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAG 1117

Query: 522  PLGA 525
            P G+
Sbjct: 1118 PAGS 1121



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 41/132 (31%), Positives = 48/132 (36%), Gaps = 25/132 (18%)

Query: 412  EKAPTARGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGA----APYAPPAP 467
            EK P  +G  GR  V  P   P P    G+PGE    G       KG+        PP P
Sbjct: 1094 EKGP--QGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGP 1151

Query: 468  SRSALAHPISLMTLPGEAGAAGLAPPGHAAAFG-----------GPPGGLLLDALPGPYA 516
                L  P+    + G  G  G  P G    FG           GPPG + L  LPGP  
Sbjct: 1152 P--GLQGPVGAPGIAGGDGEPG--PRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPG 1207

Query: 517  AAA----AGPLG 524
                    GP+G
Sbjct: 1208 EKGENGDVGPMG 1219



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 40/112 (35%), Positives = 44/112 (39%), Gaps = 19/112 (16%)

Query: 425  VVPPPPPAPRPGPV--------LGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPI 476
            VV P  P    GP+         G PGE  L GAA    GK  A   P     S    P 
Sbjct: 968  VVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAA----GKEGAKGDPGPQGISGKDGPA 1023

Query: 477  SLMTLPGEAGAAGL-APPGHAAAFG--GPPGGLLLDALPGPY-AAAAAGPLG 524
             L   PGE G  G    PG     G  GPPG +     PG   +A  AGP+G
Sbjct: 1024 GLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPV---GSPGERGSAGTAGPIG 1072



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 38/119 (31%), Positives = 42/119 (35%), Gaps = 27/119 (22%)

Query: 418 RGLEGRQVVPPPPPAPRPGPV--------LGAPGELALAG-----AAAAYPG-KG----A 459
           RG++G     PP P  +PG           G PGE    G          PG KG     
Sbjct: 564 RGVQG-----PPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGER 618

Query: 460 APYAPPAP----SRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGP 514
            P  PP P            I    LPGEAG  GL  P       G PG   +D  PGP
Sbjct: 619 GPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGP 677



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 50/173 (28%), Positives = 61/173 (35%), Gaps = 40/173 (23%)

Query: 427 PPPPPAPRPGPVLGAPGELALAGAA----AAYPGKGAAPYAPPAPSRSALAHPISLMT-L 481
           P  PP    GP  G P E  +   +     AY  KG            A+  P  L+   
Sbjct: 393 PTSPPNEEFGP--GVPAETDITETSINGHGAYGEKGQK-------GEPAVVEPGMLVEGP 443

Query: 482 PGEAGAAG-LAPPGHAAAFG--------GPPG--GLL-LDALPGPYAAAAAGPLGAAPDR 529
           PG AG AG + PPG     G        GPPG  GL   D LPGP      G +   P R
Sbjct: 444 PGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGP-----PGTMLMLPFR 498

Query: 530 FPADLDLDMFSGSLECDVESIILNDFMDSDEMDFNFDSALPPPPPGLAGAPPP 582
           +  D        + E   ++I+                  PP P GL G P P
Sbjct: 499 YGGDGSKGPTISAQEAQAQAIL---------QQARIALRGPPGPMGLTGRPGP 542



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 51/170 (30%), Positives = 57/170 (33%), Gaps = 64/170 (37%)

Query: 415  PTARGLEGRQ-------------------VVPPPPPAPRPGP-----VLGAPGELALAGA 450
            P A G EGRQ                    V P  PA +PGP     + G  GE  L GA
Sbjct: 1365 PGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGA 1424

Query: 451  AAAYPGKGAAPYAPPA--------PSRSALAHP--ISLMT------------LPGEAGAA 488
            A      G  P  PP          S+    HP  I L+             LPG  G+ 
Sbjct: 1425 AGQDGPPG--PMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSP 1482

Query: 489  GL----APPGHAAAFG--GPPGGLLLDALPGPYA----AAAAGPLGAAPD 528
            G       PG A   G  GPPG      LPGP        + GP G   D
Sbjct: 1483 GAKGDGGIPGPAGPLGPPGPPG------LPGPQGPKGNKGSTGPAGQKGD 1526



 Score = 33.1 bits (74), Expect = 0.73
 Identities = 35/121 (28%), Positives = 38/121 (31%), Gaps = 22/121 (18%)

Query: 418 RGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPIS 477
           RGL G +  P  P  P    V G PG     G      G+   P     P    L  P  
Sbjct: 651 RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQ----GEPGPPGQQGNPGPQGLPGPQG 706

Query: 478 LMTLPGEAGAAGL----------APPGHAAAFG--------GPPGGLLLDALPGPYAAAA 519
            +  PGE G  G            PPGH    G        GPPG       PGP     
Sbjct: 707 PIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKG 766

Query: 520 A 520
           A
Sbjct: 767 A 767



 Score = 33.1 bits (74), Expect = 0.73
 Identities = 51/177 (28%), Positives = 57/177 (32%), Gaps = 44/177 (24%)

Query: 427  PPPPPAPR-PGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPISLMTLPGEA 485
            PP PP PR P    GA G     G+  +  G G                        GE 
Sbjct: 1220 PPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK----------------------GEP 1257

Query: 486  GAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAA----AAGPLG-------AAPDRFPADL 534
            G AG   P   A  GGP G        GP  AA    A GP G         P  FP D 
Sbjct: 1258 GEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDP 1317

Query: 535  DLDMFSGSLECDVESIILNDFMDSDE-MDFNFDSALPPPPPGLAGAP-PPNQSWVPG 589
                  G            D +  D+  D +     PP P G AG P PP +   PG
Sbjct: 1318 GPPGEPGPAG--------QDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPG 1366



 Score = 32.3 bits (72), Expect = 1.3
 Identities = 106/414 (25%), Positives = 134/414 (32%), Gaps = 80/414 (19%)

Query: 138 KVGASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRAPSSSFVLRGSP 197
           K G  G  G  G R G+PG     G +  R  +G    PG       R P      +G P
Sbjct: 575 KPGKRGRPGADGGR-GMPGEP---GAKGDRGFDGLPGLPGDKGHRGERGP------QGPP 624

Query: 198 APRADGG-----GEVTFPEVATCEVVDLGI-GPQARAFSVPLGASLQGWGTAAGPSPELG 251
            P  D G     GE+  P     E    G+ GP+      P    + G     GP   +G
Sbjct: 625 GPPGDDGMRGEDGEIG-PRGLPGEAGPRGLLGPRGTP-GAPGQPGMAGVDGPPGPKGNMG 682

Query: 252 SGQGWLPFYPFSTADPSAEDLHMASGPWHHPGHIFCQEEAWTENLNFTPDGRAN--GLPR 309
             QG  P  P    +P  + L    GP   PG                P G+    GLP 
Sbjct: 683 P-QGE-PGPPGQQGNPGPQGLPGPQGPIGPPGEK-------------GPQGKPGLAGLPG 727

Query: 310 ALNQGLQRTRQGKAGKSQLL--PSKARKCQRQGAWGPEESDQCLELGQYLDQEVEATRTG 367
           A        ++G++G+   L  P         G  G + +D    L      + E    G
Sbjct: 728 ADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLK---GSKGEKGEDG 784

Query: 368 LAKAGSDMGSTGDWHSRIKKRMYGEMAEVFWRVNGDFATHCGDFEKAPTA-------RGL 420
                 DMG  GD          GE+ ++  R  G+           PT         G 
Sbjct: 785 FPGFKGDMGLKGD---------RGEVGQIGPR--GEDGPEGPKGRAGPTGDPGPSGQAGE 833

Query: 421 EGRQVVPPPPPAP-RPGP--------VLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSA 471
           +G+  VP  P  P R GP          GA GE    G A     +G      P  SR A
Sbjct: 834 KGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGA 893

Query: 472 LAHPISLMTLPGEAGAAGL-APPGHAAAFG-----------GPPGGLLLDALPG 513
              P       G +G  G   PPG     G           GPPG    D LPG
Sbjct: 894 RG-PTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPG 946



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 26/78 (33%), Positives = 31/78 (39%), Gaps = 2/78 (2%)

Query: 128  KGDSNSSA-GWKVGASGWGGGWGRRLGLPGAARCVGLQEGRQKEGFLAPPGVTESCSSRA 186
            KGD        K G +G  G  G R GLPGA    GL+ G   +G   P G      S  
Sbjct: 1008 KGDPGPQGISGKDGPAGLRGFPGER-GLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAG 1066

Query: 187  PSSSFVLRGSPAPRADGG 204
             +    L G P P+   G
Sbjct: 1067 TAGPIGLPGRPGPQGPPG 1084



 Score = 30.4 bits (67), Expect = 4.8
 Identities = 43/166 (25%), Positives = 55/166 (33%), Gaps = 24/166 (14%)

Query: 415  PTARGLEGRQVVPPPPPAPRPGPVL----------GAPGELALAGAAAAYPGKG-----A 459
            P A G +G    PP P  P   P L          G PG + L G       KG      
Sbjct: 1422 PGAAGQDG----PPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPG 1477

Query: 460  APYAPPAPSRSALAHPISLMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAA 519
               +P A     +  P   +  PG  G  G   P       GP G      LPGP    +
Sbjct: 1478 TQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGP--PGS 1535

Query: 520  AGPLGAAPDRFP--ADLDLDMFSGSLECDVESIILNDFMDSDEMDF 563
             GP G      P  +       +  ++ D +  IL D+ D  E  F
Sbjct: 1536 PGPPGEVIQPLPILSSKKTRRHTEGMQADADDNIL-DYSDGMEEIF 1580



 Score = 30.0 bits (66), Expect = 6.2
 Identities = 32/107 (29%), Positives = 37/107 (34%), Gaps = 6/107 (5%)

Query: 418  RGLEGRQVVPPPPPAPRPGPVLGAPGELALAGAAAAYPGKGAAPYAPPAPSRSALAHPIS 477
            +G  G +    PP A  P    G PG+    G     PG    P  P  P     A    
Sbjct: 1275 KGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGN----PGPVGFPGDPGPPGEPGPAGQDG 1330

Query: 478  LMTLPGEAGAAGLAPPGHAAAFGGPPGGLLLDALPGPYAAAAAGPLG 524
            +    GE G  G   P   +   GPPG       PG  AA A G  G
Sbjct: 1331 VGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPG--AAGAEGRQG 1375


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.135    0.434 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,381,065
Number of Sequences: 37866
Number of extensions: 1981270
Number of successful extensions: 18383
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 279
Number of HSP's successfully gapped in prelim test: 786
Number of HSP's that attempted gapping in prelim test: 11210
Number of HSP's gapped (non-prelim): 6094
length of query: 589
length of database: 18,247,518
effective HSP length: 108
effective length of query: 481
effective length of database: 14,157,990
effective search space: 6809993190
effective search space used: 6809993190
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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