Guide to the Human Genome
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Search of human proteins with 239747300

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239747300 PREDICTED: hypothetical protein XP_002346414 [Homo
sapiens]
         (470 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239747300 PREDICTED: hypothetical protein XP_002346414 [Homo ...   966   0.0  
gi|239741124 PREDICTED: hypothetical protein XP_002342114 [Homo ...   966   0.0  
gi|239752764 PREDICTED: hypothetical protein [Homo sapiens]           480   e-135
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       55   1e-07
gi|19924097 synapsin I isoform Ib [Homo sapiens]                       55   1e-07
gi|118402590 myosin XV [Homo sapiens]                                  53   7e-07
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      52   1e-06
gi|169194607 PREDICTED: hypothetical protein [Homo sapiens]            52   2e-06
gi|169201944 PREDICTED: hypothetical protein [Homo sapiens]            52   2e-06
gi|169192119 PREDICTED: hypothetical protein [Homo sapiens]            52   2e-06
gi|156071470 hyperpolarization activated cyclic nucleotide-gated...    50   4e-06
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    47   3e-05
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    47   3e-05
gi|169206489 PREDICTED: hypothetical protein [Homo sapiens]            47   3e-05
gi|169205942 PREDICTED: hypothetical protein [Homo sapiens]            47   3e-05
gi|239757331 PREDICTED: hypothetical protein [Homo sapiens]            46   6e-05
gi|239751841 PREDICTED: hypothetical protein [Homo sapiens]            46   6e-05
gi|239746332 PREDICTED: hypothetical protein XP_002343733 [Homo ...    46   6e-05
gi|169168202 PREDICTED: hypothetical protein [Homo sapiens]            45   1e-04
gi|169167967 PREDICTED: hypothetical protein [Homo sapiens]            45   1e-04
gi|169167681 PREDICTED: hypothetical protein [Homo sapiens]            45   1e-04
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]       45   2e-04
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]       45   2e-04
gi|23510413 sorting nexin 26 [Homo sapiens]                            45   2e-04
gi|239757110 PREDICTED: hypothetical protein [Homo sapiens]            44   3e-04
gi|239751535 PREDICTED: hypothetical protein [Homo sapiens]            44   3e-04
gi|239746046 PREDICTED: hypothetical protein XP_002343643 [Homo ...    44   3e-04
gi|169162152 PREDICTED: hypothetical protein [Homo sapiens]            44   4e-04
gi|239746104 PREDICTED: hypothetical protein XP_002344198 [Homo ...    44   4e-04
gi|169161145 PREDICTED: hypothetical protein [Homo sapiens]            44   4e-04

>gi|239747300 PREDICTED: hypothetical protein XP_002346414 [Homo
           sapiens]
          Length = 470

 Score =  966 bits (2498), Expect = 0.0
 Identities = 470/470 (100%), Positives = 470/470 (100%)

Query: 1   MMLAENRKACSSAFMTWALGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTR 60
           MMLAENRKACSSAFMTWALGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTR
Sbjct: 1   MMLAENRKACSSAFMTWALGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTR 60

Query: 61  LRRRRQGAVIVGRRRACPGRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPR 120
           LRRRRQGAVIVGRRRACPGRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPR
Sbjct: 61  LRRRRQGAVIVGRRRACPGRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPR 120

Query: 121 RRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAG 180
           RRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAG
Sbjct: 121 RRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAG 180

Query: 181 LWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDPGPIVGGRPE 240
           LWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDPGPIVGGRPE
Sbjct: 181 LWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDPGPIVGGRPE 240

Query: 241 NEDSPRFPDVPTRPAGPSPFYCEGTEPGSQAWSARAGTASWETAAAQRPDQLEETRPPGA 300
           NEDSPRFPDVPTRPAGPSPFYCEGTEPGSQAWSARAGTASWETAAAQRPDQLEETRPPGA
Sbjct: 241 NEDSPRFPDVPTRPAGPSPFYCEGTEPGSQAWSARAGTASWETAAAQRPDQLEETRPPGA 300

Query: 301 ARPGARRLRSLASRLPRGGRWLDGGGSGRLTREPASLPNPIPPGSRVGAGGSERQNSKRI 360
           ARPGARRLRSLASRLPRGGRWLDGGGSGRLTREPASLPNPIPPGSRVGAGGSERQNSKRI
Sbjct: 301 ARPGARRLRSLASRLPRGGRWLDGGGSGRLTREPASLPNPIPPGSRVGAGGSERQNSKRI 360

Query: 361 VYAGPGELRELVEVGEPKSDPLLWEAGLDRAQVLGLRRRKTAHALDAAPPPAGTRAGTIS 420
           VYAGPGELRELVEVGEPKSDPLLWEAGLDRAQVLGLRRRKTAHALDAAPPPAGTRAGTIS
Sbjct: 361 VYAGPGELRELVEVGEPKSDPLLWEAGLDRAQVLGLRRRKTAHALDAAPPPAGTRAGTIS 420

Query: 421 SRISSGHWEPPILAFRIVGKQVYPPARPRLPAPPRGSQRRIYEASKPHSD 470
           SRISSGHWEPPILAFRIVGKQVYPPARPRLPAPPRGSQRRIYEASKPHSD
Sbjct: 421 SRISSGHWEPPILAFRIVGKQVYPPARPRLPAPPRGSQRRIYEASKPHSD 470


>gi|239741124 PREDICTED: hypothetical protein XP_002342114 [Homo
           sapiens]
          Length = 470

 Score =  966 bits (2498), Expect = 0.0
 Identities = 470/470 (100%), Positives = 470/470 (100%)

Query: 1   MMLAENRKACSSAFMTWALGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTR 60
           MMLAENRKACSSAFMTWALGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTR
Sbjct: 1   MMLAENRKACSSAFMTWALGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTR 60

Query: 61  LRRRRQGAVIVGRRRACPGRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPR 120
           LRRRRQGAVIVGRRRACPGRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPR
Sbjct: 61  LRRRRQGAVIVGRRRACPGRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPR 120

Query: 121 RRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAG 180
           RRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAG
Sbjct: 121 RRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAG 180

Query: 181 LWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDPGPIVGGRPE 240
           LWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDPGPIVGGRPE
Sbjct: 181 LWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDPGPIVGGRPE 240

Query: 241 NEDSPRFPDVPTRPAGPSPFYCEGTEPGSQAWSARAGTASWETAAAQRPDQLEETRPPGA 300
           NEDSPRFPDVPTRPAGPSPFYCEGTEPGSQAWSARAGTASWETAAAQRPDQLEETRPPGA
Sbjct: 241 NEDSPRFPDVPTRPAGPSPFYCEGTEPGSQAWSARAGTASWETAAAQRPDQLEETRPPGA 300

Query: 301 ARPGARRLRSLASRLPRGGRWLDGGGSGRLTREPASLPNPIPPGSRVGAGGSERQNSKRI 360
           ARPGARRLRSLASRLPRGGRWLDGGGSGRLTREPASLPNPIPPGSRVGAGGSERQNSKRI
Sbjct: 301 ARPGARRLRSLASRLPRGGRWLDGGGSGRLTREPASLPNPIPPGSRVGAGGSERQNSKRI 360

Query: 361 VYAGPGELRELVEVGEPKSDPLLWEAGLDRAQVLGLRRRKTAHALDAAPPPAGTRAGTIS 420
           VYAGPGELRELVEVGEPKSDPLLWEAGLDRAQVLGLRRRKTAHALDAAPPPAGTRAGTIS
Sbjct: 361 VYAGPGELRELVEVGEPKSDPLLWEAGLDRAQVLGLRRRKTAHALDAAPPPAGTRAGTIS 420

Query: 421 SRISSGHWEPPILAFRIVGKQVYPPARPRLPAPPRGSQRRIYEASKPHSD 470
           SRISSGHWEPPILAFRIVGKQVYPPARPRLPAPPRGSQRRIYEASKPHSD
Sbjct: 421 SRISSGHWEPPILAFRIVGKQVYPPARPRLPAPPRGSQRRIYEASKPHSD 470


>gi|239752764 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 370

 Score =  480 bits (1235), Expect = e-135
 Identities = 261/367 (71%), Positives = 264/367 (71%), Gaps = 47/367 (12%)

Query: 1   MMLAENRKACSSAFMTWALGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTR 60
           MMLAENRKACSSAFMTWALGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTR
Sbjct: 1   MMLAENRKACSSAFMTWALGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTR 60

Query: 61  LRRRRQGAVIVGRRRACPGRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPR 120
           LRRRRQGAVIVGRRRACPGRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPR
Sbjct: 61  LRRRRQGAVIVGRRRACPGRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPR 120

Query: 121 RRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAG 180
           RRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAG
Sbjct: 121 RRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAG 180

Query: 181 LWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHAR------------------------- 215
           LWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHAR                         
Sbjct: 181 LWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARTLSLPAPSPAPCLPPPAPPAARTPS 240

Query: 216 AHSRAHT----------------CAGGGEGDPGPIVGGRPENEDSPRFPDVPTRPAGPSP 259
           AHS AHT                  GGGEGDPGPIVGGRPENEDS      P  P  P P
Sbjct: 241 AHSPAHTHFTLTLAEAHTRALTPARGGGEGDPGPIVGGRPENEDSLASQTSPPAPPAPVP 300

Query: 260 FYCEGTEPGSQAWSARAGTASWETAAAQRPDQLEETRPPGAARPGAR-RLRSLASRLPRG 318
                  PG     AR G       A +R      T     AR   R R  ++    PRG
Sbjct: 301 STARARSPG-----ARRGARELAPRAGRRRQPSGRTSWRRRARREQRDREPAVCGAWPRG 355

Query: 319 GRWLDGG 325
                 G
Sbjct: 356 SHAAGAG 362


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 82/295 (27%), Positives = 102/295 (34%), Gaps = 79/295 (26%)

Query: 73  RRRACPGRGRGG---LPGAAALGAGAQQPRRRRLAQ--PPGSRAPLQVGGAPRRRAHLTG 127
           +R A PGRG  G    PGA  LG    Q      AQ  PP    P Q G  P+R+    G
Sbjct: 423 QRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQ----G 478

Query: 128 GPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCT 187
            P ++RPP     H        GL P           A + LP+ LP   +A        
Sbjct: 479 PPLQQRPPPQGQQH------LSGLGPP----------AGSPLPQRLPSPTSA-------- 514

Query: 188 RLRPLLLQPPPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDP---GPIVGGRPENEDS 244
             +P     PP    G    P                 GG G P    P     P+ +  
Sbjct: 515 PQQPASQAAPPTQGQGRQSRP---------------VAGGPGAPPAARPPASPSPQRQAG 559

Query: 245 PRFPDVPTRPAGPSPFYCEGTEPGSQAWSARAGTASWETAAAQRPDQLEETRPPGAARPG 304
           P      T  +GP+P    G  PG Q                Q P Q    +PPG A  G
Sbjct: 560 PPQATRQTSVSGPAPPKASGAPPGGQ--------------QRQGPPQ----KPPGPA--G 599

Query: 305 ARRLRSLASRLPRGG-------RWLDGGGSGRLTREPASLPN-PIPPGSRVGAGG 351
             R  S A  +PR G       R    G +GR   + A  P+  +PP +   AGG
Sbjct: 600 PTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGG 654



 Score = 37.0 bits (84), Expect = 0.039
 Identities = 50/181 (27%), Positives = 62/181 (34%), Gaps = 38/181 (20%)

Query: 19  LGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTRLRRRRQGAVIVGRRRACP 78
           LGP A S +P RLP       P  +  Q A   +P    Q R  R              P
Sbjct: 496 LGPPAGSPLPQRLP------SPTSAPQQPASQAAPPTQGQGRQSR--------------P 535

Query: 79  GRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGG--APRRRAHLTGGPPRRRPPR 136
             G  G P AA   A    P  +R A PP +     V G   P+      GG  R+ PP+
Sbjct: 536 VAGGPGAPPAARPPA---SPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQ 592

Query: 137 LAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQP 196
                  P    P  +   A    R    + + PR   P PA         R +P L Q 
Sbjct: 593 KP-----PGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAG--------RPKPQLAQK 639

Query: 197 P 197
           P
Sbjct: 640 P 640


>gi|19924097 synapsin I isoform Ib [Homo sapiens]
          Length = 669

 Score = 55.1 bits (131), Expect = 1e-07
 Identities = 82/295 (27%), Positives = 102/295 (34%), Gaps = 79/295 (26%)

Query: 73  RRRACPGRGRGG---LPGAAALGAGAQQPRRRRLAQ--PPGSRAPLQVGGAPRRRAHLTG 127
           +R A PGRG  G    PGA  LG    Q      AQ  PP    P Q G  P+R+    G
Sbjct: 423 QRDASPGRGSHGQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQ----G 478

Query: 128 GPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCT 187
            P ++RPP     H        GL P           A + LP+ LP   +A        
Sbjct: 479 PPLQQRPPPQGQQH------LSGLGPP----------AGSPLPQRLPSPTSA-------- 514

Query: 188 RLRPLLLQPPPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDP---GPIVGGRPENEDS 244
             +P     PP    G    P                 GG G P    P     P+ +  
Sbjct: 515 PQQPASQAAPPTQGQGRQSRP---------------VAGGPGAPPAARPPASPSPQRQAG 559

Query: 245 PRFPDVPTRPAGPSPFYCEGTEPGSQAWSARAGTASWETAAAQRPDQLEETRPPGAARPG 304
           P      T  +GP+P    G  PG Q                Q P Q    +PPG A  G
Sbjct: 560 PPQATRQTSVSGPAPPKASGAPPGGQ--------------QRQGPPQ----KPPGPA--G 599

Query: 305 ARRLRSLASRLPRGG-------RWLDGGGSGRLTREPASLPN-PIPPGSRVGAGG 351
             R  S A  +PR G       R    G +GR   + A  P+  +PP +   AGG
Sbjct: 600 PTRQASQAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQKPSQDVPPPATAAAGG 654



 Score = 37.0 bits (84), Expect = 0.039
 Identities = 50/181 (27%), Positives = 62/181 (34%), Gaps = 38/181 (20%)

Query: 19  LGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTRLRRRRQGAVIVGRRRACP 78
           LGP A S +P RLP       P  +  Q A   +P    Q R  R              P
Sbjct: 496 LGPPAGSPLPQRLP------SPTSAPQQPASQAAPPTQGQGRQSR--------------P 535

Query: 79  GRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGG--APRRRAHLTGGPPRRRPPR 136
             G  G P AA   A    P  +R A PP +     V G   P+      GG  R+ PP+
Sbjct: 536 VAGGPGAPPAARPPA---SPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQ 592

Query: 137 LAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQP 196
                  P    P  +   A    R    + + PR   P PA         R +P L Q 
Sbjct: 593 KP-----PGPAGPTRQASQAGPVPRTGPPTTQQPRPSGPGPAG--------RPKPQLAQK 639

Query: 197 P 197
           P
Sbjct: 640 P 640


>gi|118402590 myosin XV [Homo sapiens]
          Length = 3530

 Score = 52.8 bits (125), Expect = 7e-07
 Identities = 96/355 (27%), Positives = 116/355 (32%), Gaps = 63/355 (17%)

Query: 39  IPRESGIQKAHTRSPAQYSQTRLRRRRQGAVIVGRRRACPGRGRGGLPGAAALGAGAQQP 98
           I R  G QKA    PA         +R G  + G     PG           +     QP
Sbjct: 586 IARLRGSQKARAGGPAVREAAY---KRFGYKLAGMDPEKPG---------TPIVLRRAQP 633

Query: 99  RRRRLAQPPGSRAPLQVGGAPRRRAH---LTGGPPRRRPPRLAAAHGLPASEA-PGL-RP 153
           R R       +R P     APR  +H   L   P   RPP        P S A  GL RP
Sbjct: 634 RAR---SSNDARRPPAPQPAPRTLSHWSALLSPPVPPRPPSSGPPPAPPLSPALSGLPRP 690

Query: 154 DSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQPP---PMLSPGLAQSPGV 210
            S    LR        P  +PPAP A  W           ++PP   P + P L   PG 
Sbjct: 691 ASPYGSLRRHPPPWAAPAHVPPAPQASWWA---------FVEPPAVSPEVPPDLLAFPGP 741

Query: 211 ELHARAHSRAHTCAGGGEGDPGPIVGGRPENEDSPRFPDVPTRPAGPSPFYCEGTEPGSQ 270
               R   R     G   G PG           SP     P+  + P   YC    P S 
Sbjct: 742 RPSFRGSRRR----GAAFGFPGASPRASRRRAWSPLASPQPSLRSSPGLGYCSPLAPPSP 797

Query: 271 AWSARAGTASWE-TAAAQRPDQLEET----------RPPGAARPGARRLRS--------- 310
             S R G         A+RP  L+E+           PPG+  PG+ R  S         
Sbjct: 798 QLSLRTGPFQPPFLPPARRPRSLQESPAPRRAAGRLGPPGSPLPGSPRPPSPPLGLCHSP 857

Query: 311 ------LASRLPRGGRWLDGGGSGRLTREPASLPNPIPPGSRVGAGGSERQNSKR 359
                 L SRLP   R L    + R  +    LP   PP +       E + S R
Sbjct: 858 RRSSLNLPSRLPHTWRRLSEPPT-RAVKPQVRLPFHRPPRAGAWRAPLEHRESPR 911


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 103/408 (25%), Positives = 133/408 (32%), Gaps = 101/408 (24%)

Query: 78  PG-RGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPR 136
           PG +G  GLPG          P        PG +      GAP  +    G P  R PP 
Sbjct: 635 PGPQGLQGLPGTGG------PPGENGKPGEPGPKGDAGAPGAPGGKGD-AGAPGERGPPG 687

Query: 137 LAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQP 196
           LA A        PGLR  +                  PP P  G   AG           
Sbjct: 688 LAGA--------PGLRGGAG-----------------PPGPEGGKGAAG----------- 711

Query: 197 PPMLSPGLAQSPGVE-LHARAHSRAHTCAGGGEGDPG-PIVGGRPENEDSPRFPDVPTRP 254
            P   PG A +PG++ +             G +G+PG P   G P  +D PR P  P  P
Sbjct: 712 -PPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVP-GKDGPRGPTGPIGP 769

Query: 255 AGPSPFYCEGTE---------------PGSQAWSARAGTASWETAAAQR----------- 288
            GP+    +  E               PG +  +   G A +  A  Q            
Sbjct: 770 PGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGA 829

Query: 289 PDQLEETRPPGAARP--GARRLRSLASRLPRGGRWLDGG-------GSGRLTREPASLPN 339
           P +  E  PPG A P  G+        +  +G R   GG       G+  L   P S  N
Sbjct: 830 PGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGN 889

Query: 340 PIPPG--------------SRVGAGGSERQNSKRIVYAGPGELRELVEVGEPKSDPLLWE 385
           P PPG                 GA GS   +  +     PGE       G P +   L  
Sbjct: 890 PGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGI 949

Query: 386 AGLDRAQVLGLRRRKTAHALDAAPPPAGTR--AGTISSRISSGHWEPP 431
           AG+  A+  GL           +P P G +  +G   +   SG   PP
Sbjct: 950 AGITGAR--GLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPP 995



 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 89/332 (26%), Positives = 109/332 (32%), Gaps = 78/332 (23%)

Query: 78  PGR-GRGGLPGAAA-LGA-------------GAQQPRRRRLAQPPGSRAPLQVGGAPRRR 122
           PG  G  GLPGAA   GA             G + P   R A  PG   P    G P R 
Sbjct: 470 PGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGA--PGPAGPRGAAGEPGRD 527

Query: 123 AHLTGGPPRRRPPRLAAAHGLPASEA----PGLRPDSARTRLRLRLASARLPRGLPPAPA 178
             + GGP  R  P    + G P S+     PG + +S R                PP P+
Sbjct: 528 G-VPGGPGMRGMP---GSPGGPGSDGKPGPPGSQGESGRPG--------------PPGPS 569

Query: 179 AGLWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDPGPIVGGR 238
                              P   PG+   PG + +  A  +      GG G PGP     
Sbjct: 570 G------------------PRGQPGVMGFPGPKGNDGAPGK--NGERGGPGGPGPQGPPG 609

Query: 239 PENEDSPRFPDVPTRPAGPSPFYCEGTEPGSQAWSARAGTAS--WETAAAQRPDQLEETR 296
              E  P+ P  PT P G      +   PG Q      GT     E      P    +  
Sbjct: 610 KNGETGPQGPPGPTGPGGDKG---DTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAG 666

Query: 297 PPG-------AARPGARRLRSLASRLP-RGGRWLDGGGSGRLTREPASLPNPIPPGSRVG 348
            PG       A  PG R    LA     RGG    G   G+    P     P PPG+  G
Sbjct: 667 APGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGP-----PGPPGA-AG 720

Query: 349 AGGSERQNSKRIVYAGPGELRELVEVGEPKSD 380
             G +    +R     PG   +  E G P +D
Sbjct: 721 TPGLQGMPGERGGLGSPGPKGDKGEPGGPGAD 752



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 79/281 (28%), Positives = 99/281 (35%), Gaps = 25/281 (8%)

Query: 81   GRGGLPGAAALGAGAQQPRRRRL--AQ-PPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRL 137
            G  G PG +     A QP  +    AQ PPG+  PL + G       +TG      PP +
Sbjct: 912  GAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAG-------ITGARGLAGPPGM 964

Query: 138  AAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQPP 197
                G P  +  G++ +S +      L+  R P G  P    GL  AG          P 
Sbjct: 965  PGPRGSPGPQ--GVKGESGKPGAN-GLSGERGPPG--PQGLPGL--AGTAGEPGRDGNPG 1017

Query: 198  PMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDPGPIVGGRPENEDSPRFPDVPTRPAG- 256
                PG   SPG +            A G  G PGP     P  +   R    P  PAG 
Sbjct: 1018 SDGLPGRDGSPGGK--GDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGA 1075

Query: 257  PSPFYCEGTEPGSQAWSARAGTASWETAAAQRPDQLEETRPPGAARPG-ARRLRSLASRL 315
            P P    G  PG Q      G      AA  +  +     P     PG A +  ++ S  
Sbjct: 1076 PGPAGSRGA-PGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPG 1134

Query: 316  PRGGRWLDGGGSGRLTREPASLPNPI-PPGSRVGAG--GSE 353
            P G R   G          +  P PI PPG R   G  GSE
Sbjct: 1135 PAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSE 1175



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 69/244 (28%), Positives = 79/244 (32%), Gaps = 34/244 (13%)

Query: 81  GRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAH-----LTGGPPRRRPP 135
           G  G PG         +P  R L  PPG + P  + G P  + H       G       P
Sbjct: 231 GESGRPG---------RPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAP 281

Query: 136 RLAAAHGLPASE-APGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLL 194
            L   +GLP    APG  P   R         A   RG P  P A   R G    R    
Sbjct: 282 GLKGENGLPGENGAPG--PMGPR--------GAPGERGRPGLPGAAGAR-GNDGARGSDG 330

Query: 195 QPPPMLSPGLA---QSPGVELH-ARAHSRAHTCAGGGEGDPGPIVGGRPENEDSPRFPDV 250
           QP P   PG A    SPG +     A S     A G  G+PGP   G    +  P  P +
Sbjct: 331 QPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGP--QGHAGAQGPPGPPGI 388

Query: 251 PTRPAGPSPFYCEGT--EPGSQAWSARAGTASWETAAAQRPDQLEETRPPGAARPGARRL 308
              P G       G    PG        G A    A   R    E  +      PG R  
Sbjct: 389 NGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGE 448

Query: 309 RSLA 312
           R  A
Sbjct: 449 RGEA 452



 Score = 40.4 bits (93), Expect = 0.003
 Identities = 78/295 (26%), Positives = 101/295 (34%), Gaps = 42/295 (14%)

Query: 70   IVGRRRACPGRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGP 129
            + G R +  G G  G PGA            R L  PPGS       G        +G P
Sbjct: 859  VKGERGSPGGPGAAGFPGA------------RGLPGPPGSNGNPGPPGP-------SGSP 899

Query: 130  PRRRPPRLAAAHGLPASE-APGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTR 188
             +  PP  A   G P S    G + D+ +   +     +   +G P AP   L  AG T 
Sbjct: 900  GKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEK----GSPGAQGPPGAPGP-LGIAGITG 954

Query: 189  LRPLLLQPPPMLSPGLAQSPGVE-LHARAHSRAHTCAGGGEGDPGPI-------VGGRPE 240
             R  L  PP M  PG   SPG + +   +         G  G PGP          G P 
Sbjct: 955  ARG-LAGPPGM--PGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPG 1011

Query: 241  NEDSPRFPDVPTRPAGPSPFYCEGT--EPGSQAWSARAGTASWETAAAQRPDQLEE--TR 296
             + +P    +P R   P      G    PG+       G       A +  D+ E     
Sbjct: 1012 RDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAG 1071

Query: 297  PPGAARPGARRLRSLASRLPRGGRWLDGGGSGRLTREPASLP-NPIPPGSRVGAG 350
            P GA  P   R  +   + PRG +   G       +     P NP  PGS   AG
Sbjct: 1072 PAGAPGPAGSR-GAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAG 1125



 Score = 36.2 bits (82), Expect = 0.066
 Identities = 83/323 (25%), Positives = 112/323 (34%), Gaps = 53/323 (16%)

Query: 46  QKAHTRSPAQYSQTRLRRRRQGAVIVGRRRACPGRGRGGLPGAAALGAGAQQPRRRRLAQ 105
           +K  T +P    +  L         +G R A   RGR GLPGAA  GA      R    Q
Sbjct: 274 EKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAA--GARGNDGARGSDGQ 331

Query: 106 PPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLA 165
            PG   P    G P       G P  +     A + G  ++ APG R +          A
Sbjct: 332 -PGPPGPPGTAGFP-------GSPGAKGEVGPAGSPG--SNGAPGQRGEPGPQ----GHA 377

Query: 166 SARLPRGLP-----PAPAAGLWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARAHSRA 220
            A+ P G P     P     +  AG      L+    P    G   +PG+   A    + 
Sbjct: 378 GAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGK- 436

Query: 221 HTCAGGGEGDPGPIVGGRPENEDSPRFPDVPTRPAGPSPFYCEGTEPGSQAWSARAGTAS 280
                G +G+PGP    R E  ++     +P  P        +G+ PG    +   G A 
Sbjct: 437 ----NGAKGEPGP----RGERGEA----GIPGVPGAKGEDGKDGS-PGEPGANGLPGAAG 483

Query: 281 WETAAAQR----PDQLEETRPPGAAR--PGARRLRSLASRLPRGG-------RWLDGGGS 327
              A   R    P+ +   + P   R  PG    R  A    R G       R + G   
Sbjct: 484 ERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPG 543

Query: 328 GRLTREPASLPNPIPPGSRVGAG 350
           G     P S   P PPGS+  +G
Sbjct: 544 G-----PGSDGKPGPPGSQGESG 561


>gi|169194607 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 436

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 86/304 (28%), Positives = 110/304 (36%), Gaps = 54/304 (17%)

Query: 21  PSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTRLRRRRQGAVIVGRRRACPGR 80
           PS  +K     P      IP   G + + +R      ++RL RR    +I          
Sbjct: 120 PSPRAKAHAHAPTHSLLSIP---GAKTSRSRCSPSPGRSRLARRPLAHLIQAVDFL---- 172

Query: 81  GRGGLPGAAALGA------GAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRP 134
             GG+   +A GA      G++  RRRRL              APR R  +    PRR P
Sbjct: 173 --GGIHDFSATGALGVHDRGSRGRRRRRLL-------------APRSRCDI----PRRAP 213

Query: 135 PRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCT--RLRPL 192
            RL A      +   G R  S R   R  +  AR  R L P P     RAG T  R R  
Sbjct: 214 HRLLAGG---RAAGGGRRVGSRR---RATVTRARPSRSLAPPPRRRR-RAGQTHRRARTE 266

Query: 193 LLQPPPMLSPG----LAQSPGVELHARAHSRAHTCAGGGEG-DPGPIVGGRPEN-EDSPR 246
           +     +  PG      +  G +  + A  R   CA  G    P P+  G P      PR
Sbjct: 267 VAGNVHVGHPGREGAAGEGAGRDPESSADRRGCDCAAWGVSLAPPPLQAGEPSRGHPHPR 326

Query: 247 FPDVP-------TRPAGPSPFYCEGTEPGSQAWSARAGTASWETAAAQRPDQLEETRPPG 299
             DVP        R  G      +  +PG+ A S RA   S   + A RP   E    PG
Sbjct: 327 LTDVPGTQMSRGVRGQGAPSLLLQPVKPGTAAPSPRAEAVSAARSDAPRPKGREIRGEPG 386

Query: 300 AARP 303
             RP
Sbjct: 387 DLRP 390



 Score = 30.4 bits (67), Expect = 3.6
 Identities = 56/199 (28%), Positives = 69/199 (34%), Gaps = 34/199 (17%)

Query: 19  LGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTR---------LRRRRQGAV 69
           L P +   IP R P R+  G     G ++  +R  A  ++ R          RRRR G  
Sbjct: 200 LAPRSRCDIPRRAPHRLLAGGRAAGGGRRVGSRRRATVTRARPSRSLAPPPRRRRRAGQT 259

Query: 70  IVGRRRACPGR---GRGGLPGAAALGAG--AQQPRRRR----------LAQPPGSRAPLQ 114
               R    G    G  G  GAA  GAG   +    RR          LA P     PLQ
Sbjct: 260 HRRARTEVAGNVHVGHPGREGAAGEGAGRDPESSADRRGCDCAAWGVSLAPP-----PLQ 314

Query: 115 VGGAPRRRAH--LTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRG 172
            G   R   H  LT   P  +  R     G P+     ++P +A    R    SA   R 
Sbjct: 315 AGEPSRGHPHPRLT-DVPGTQMSRGVRGQGAPSLLLQPVKPGTAAPSPRAEAVSA--ARS 371

Query: 173 LPPAPAAGLWRAGCTRLRP 191
             P P     R     LRP
Sbjct: 372 DAPRPKGREIRGEPGDLRP 390


>gi|169201944 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 436

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 86/304 (28%), Positives = 110/304 (36%), Gaps = 54/304 (17%)

Query: 21  PSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTRLRRRRQGAVIVGRRRACPGR 80
           PS  +K     P      IP   G + + +R      ++RL RR    +I          
Sbjct: 120 PSPRAKAHAHAPTHSLLSIP---GAKTSRSRCSPSPGRSRLARRPLAHLIQAVDFL---- 172

Query: 81  GRGGLPGAAALGA------GAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRP 134
             GG+   +A GA      G++  RRRRL              APR R  +    PRR P
Sbjct: 173 --GGIHDFSATGALGVHDRGSRGRRRRRLL-------------APRSRCDI----PRRAP 213

Query: 135 PRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCT--RLRPL 192
            RL A      +   G R  S R   R  +  AR  R L P P     RAG T  R R  
Sbjct: 214 HRLLAGG---RAAGGGRRVGSRR---RATVTRARPSRSLAPPPRRRR-RAGQTHRRARTE 266

Query: 193 LLQPPPMLSPG----LAQSPGVELHARAHSRAHTCAGGGEG-DPGPIVGGRPEN-EDSPR 246
           +     +  PG      +  G +  + A  R   CA  G    P P+  G P      PR
Sbjct: 267 VAGNVHVGHPGREGAAGEGAGRDPESSADRRGCDCAAWGVSLAPPPLQAGEPSRGHPHPR 326

Query: 247 FPDVP-------TRPAGPSPFYCEGTEPGSQAWSARAGTASWETAAAQRPDQLEETRPPG 299
             DVP        R  G      +  +PG+ A S RA   S   + A RP   E    PG
Sbjct: 327 LTDVPGTQMSRGVRGQGAPSLLLQPVKPGTAAPSPRAEAVSAARSDAPRPKGREIRGEPG 386

Query: 300 AARP 303
             RP
Sbjct: 387 DLRP 390



 Score = 30.4 bits (67), Expect = 3.6
 Identities = 56/199 (28%), Positives = 69/199 (34%), Gaps = 34/199 (17%)

Query: 19  LGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTR---------LRRRRQGAV 69
           L P +   IP R P R+  G     G ++  +R  A  ++ R          RRRR G  
Sbjct: 200 LAPRSRCDIPRRAPHRLLAGGRAAGGGRRVGSRRRATVTRARPSRSLAPPPRRRRRAGQT 259

Query: 70  IVGRRRACPGR---GRGGLPGAAALGAG--AQQPRRRR----------LAQPPGSRAPLQ 114
               R    G    G  G  GAA  GAG   +    RR          LA P     PLQ
Sbjct: 260 HRRARTEVAGNVHVGHPGREGAAGEGAGRDPESSADRRGCDCAAWGVSLAPP-----PLQ 314

Query: 115 VGGAPRRRAH--LTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRG 172
            G   R   H  LT   P  +  R     G P+     ++P +A    R    SA   R 
Sbjct: 315 AGEPSRGHPHPRLT-DVPGTQMSRGVRGQGAPSLLLQPVKPGTAAPSPRAEAVSA--ARS 371

Query: 173 LPPAPAAGLWRAGCTRLRP 191
             P P     R     LRP
Sbjct: 372 DAPRPKGREIRGEPGDLRP 390


>gi|169192119 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 436

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 86/304 (28%), Positives = 110/304 (36%), Gaps = 54/304 (17%)

Query: 21  PSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTRLRRRRQGAVIVGRRRACPGR 80
           PS  +K     P      IP   G + + +R      ++RL RR    +I          
Sbjct: 120 PSPRAKAHAHAPTHSLLSIP---GAKTSRSRCSPSPGRSRLARRPLAHLIQAVDFL---- 172

Query: 81  GRGGLPGAAALGA------GAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRP 134
             GG+   +A GA      G++  RRRRL              APR R  +    PRR P
Sbjct: 173 --GGIHDFSATGALGVHDRGSRGRRRRRLL-------------APRSRCDI----PRRAP 213

Query: 135 PRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCT--RLRPL 192
            RL A      +   G R  S R   R  +  AR  R L P P     RAG T  R R  
Sbjct: 214 HRLLAGG---RAAGGGRRVGSRR---RATVTRARPSRSLAPPPRRRR-RAGQTHRRARTE 266

Query: 193 LLQPPPMLSPG----LAQSPGVELHARAHSRAHTCAGGGEG-DPGPIVGGRPEN-EDSPR 246
           +     +  PG      +  G +  + A  R   CA  G    P P+  G P      PR
Sbjct: 267 VAGNVHVGHPGREGAAGEGAGRDPESSADRRGCDCAAWGVSLAPPPLQAGEPSRGHPHPR 326

Query: 247 FPDVP-------TRPAGPSPFYCEGTEPGSQAWSARAGTASWETAAAQRPDQLEETRPPG 299
             DVP        R  G      +  +PG+ A S RA   S   + A RP   E    PG
Sbjct: 327 LTDVPGTQMSRGVRGQGAPSLLLQPVKPGTAAPSPRAEAVSAARSDAPRPKGREIRGEPG 386

Query: 300 AARP 303
             RP
Sbjct: 387 DLRP 390



 Score = 30.4 bits (67), Expect = 3.6
 Identities = 56/199 (28%), Positives = 69/199 (34%), Gaps = 34/199 (17%)

Query: 19  LGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTR---------LRRRRQGAV 69
           L P +   IP R P R+  G     G ++  +R  A  ++ R          RRRR G  
Sbjct: 200 LAPRSRCDIPRRAPHRLLAGGRAAGGGRRVGSRRRATVTRARPSRSLAPPPRRRRRAGQT 259

Query: 70  IVGRRRACPGR---GRGGLPGAAALGAG--AQQPRRRR----------LAQPPGSRAPLQ 114
               R    G    G  G  GAA  GAG   +    RR          LA P     PLQ
Sbjct: 260 HRRARTEVAGNVHVGHPGREGAAGEGAGRDPESSADRRGCDCAAWGVSLAPP-----PLQ 314

Query: 115 VGGAPRRRAH--LTGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRG 172
            G   R   H  LT   P  +  R     G P+     ++P +A    R    SA   R 
Sbjct: 315 AGEPSRGHPHPRLT-DVPGTQMSRGVRGQGAPSLLLQPVKPGTAAPSPRAEAVSA--ARS 371

Query: 173 LPPAPAAGLWRAGCTRLRP 191
             P P     R     LRP
Sbjct: 372 DAPRPKGREIRGEPGDLRP 390


>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
           potassium channel 2 [Homo sapiens]
          Length = 889

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 51/166 (30%), Positives = 61/166 (36%), Gaps = 34/166 (20%)

Query: 129 PPRRRPPRLAAAHG-LPASEAPGLRPDSARTRLR-LRLASARLPRGLPPAPAAGLWRAGC 186
           PP   PP++ +A   L  + A    P  AR  +  L L S RL R  PP PA      G 
Sbjct: 715 PPPPPPPQVTSAIATLQQAAAMSFCPQVARPLVGPLALGSPRLVRRPPPGPAPAAASPG- 773

Query: 187 TRLRPLLLQPPPMLSPGLAQSP-----------------GVELHARAHSRAHTCAGGGE- 228
                    PPP   PG   SP                 G  L AR  SRA       + 
Sbjct: 774 --------PPPPASPPGAPASPRAPRTSPYGGLPAAPLAGPALPARRLSRASRPLSASQP 825

Query: 229 ----GDPGPIVGGRPENEDSPRFPDVP-TRPAGPSPFYCEGTEPGS 269
               G PGP    RP +  +PR    P  R A PSP   +   PG+
Sbjct: 826 SLPHGAPGPAASTRPASSSTPRLGPTPAARAAAPSPDRRDSASPGA 871



 Score = 32.7 bits (73), Expect = 0.73
 Identities = 29/98 (29%), Positives = 31/98 (31%), Gaps = 3/98 (3%)

Query: 224 AGGGEGDPGPIVGGRPENEDSPRFPDVPTR---PAGPSPFYCEGTEPGSQAWSARAGTAS 280
           A GG G PG   G  P     P  P  P +   P  P P    G  P       RA    
Sbjct: 3   ARGGGGRPGESPGATPAPGPPPPPPPAPPQQQPPPPPPPAPPPGPGPAPPQHPPRAEALP 62

Query: 281 WETAAAQRPDQLEETRPPGAARPGARRLRSLASRLPRG 318
            E A    P     +R     RPG     S A   P G
Sbjct: 63  PEAADEGGPRGRLRSRDSSCGRPGTPGAASTAKGSPNG 100


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 86/301 (28%), Positives = 101/301 (33%), Gaps = 54/301 (17%)

Query: 78  PGR-GRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPL-----QVGGAPRRRAHLTG--GP 129
           PG+ G  GLPGA  L     +      A PPG   P      Q    P     L G  GP
Sbjct: 614 PGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGP 673

Query: 130 PRR--RP-----PRLAAAHGL--PASEA--PGLRPDSARTRLRLRLASARLPRGLPPAPA 178
           P    +P     P  A A GL  P  E   PG R       L       + PRGLP  P 
Sbjct: 674 PGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGL-------QGPRGLPGTPG 726

Query: 179 AGLWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDPGPIVGGR 238
               +       P   Q P    PGL   PG         R      G +GD G +    
Sbjct: 727 TDGPKGASGPAGPPGAQGP----PGLQGMPG--------ERGAAGIAGPKGDRGDVGEKG 774

Query: 239 PE---NEDSPRFPDVPTRPAGPSPFYCEGTEPGSQAWSARAGTASWETAAAQRPDQLEET 295
           PE    +D  R    P  P GP+    E  E G    +  AG       A   P +  ET
Sbjct: 775 PEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAG-------ARGAPGERGET 827

Query: 296 RPPG----AARPGARRLRSLASRLPRGGRWLDGGGSGRLTREPASLPNPIPPGSRVGAGG 351
            PPG    A  PGA             G+  D G  G   + P+  P P  P    G  G
Sbjct: 828 GPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPG--PQGPSGAPGPQGPTGVTGPKG 885

Query: 352 S 352
           +
Sbjct: 886 A 886



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 77/323 (23%), Positives = 93/323 (28%), Gaps = 49/323 (15%)

Query: 81  GRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAP--RRRAHLTGGPPRRRPPRLA 138
           G  G PG         +P    ++ P G R P    G P     A   G    R PP   
Sbjct: 213 GPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQ 272

Query: 139 AAHGLPASE----------------------APGLRPDSARTRLRLRLASARLPRGLPPA 176
            A G P +                       APG++ +S              PRGL P 
Sbjct: 273 GARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPG-ENGSPGPMGPRGL-PG 330

Query: 177 PAAGLWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDPGPIVG 236
                  AG    R    QP P   PG     G              A G +G+ GP   
Sbjct: 331 ERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAG--------GPGFPGAPGAKGEAGPTGA 382

Query: 237 GRPENEDSPRFPDVPTRPAGPSPFYCEGTEPGSQAWSARAGTASWE--TAAAQRPDQLEE 294
             PE    PR    P  P  P P    G  PG+       G+A       A   P     
Sbjct: 383 RGPEGAQGPR--GEPGTPGSPGPAGASG-NPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP 439

Query: 295 TRPPGAARPGARRLRSLASRLPRGGRWLDGGGSGRLTREPASLPNPIPPGSRVGAGGSER 354
             P GA  P            P+G     G    +  + P   P P  P    G  G E 
Sbjct: 440 PGPQGATGPLG----------PKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEG 489

Query: 355 QNSKRIVYAGPGELRELVEVGEP 377
           +   R    G G +    E G P
Sbjct: 490 KRGARGEPGGVGPIGPPGERGAP 512



 Score = 32.3 bits (72), Expect = 0.95
 Identities = 69/246 (28%), Positives = 83/246 (33%), Gaps = 33/246 (13%)

Query: 78   PG-RGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPR 136
            PG RG  G PG   L   + +P ++      G R P    G P       G P R   P 
Sbjct: 986  PGQRGERGFPG---LPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGP-AGEPGREGSP- 1040

Query: 137  LAAAHGLPASE-APGLRPDSARTRLRLRLASARLPRGLP-PAPAAG-------------L 181
               A G P  + A G++ D   T   +    A  P G P PA   G             +
Sbjct: 1041 --GADGPPGRDGAAGVKGDRGETGA-VGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPM 1097

Query: 182  WRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDPGPIVGGRPEN 241
              +G    R +     P    G A  PG E   + H R  T   G  G PGP      + 
Sbjct: 1098 GPSGPAGARGIQGPQGPRGDKGEAGEPG-ERGLKGH-RGFTGLQGLPGPPGP---SGDQG 1152

Query: 242  EDSPRFPDVPTRPAGP-SPFYCEGTE--PGSQAWSARAGTASWETAAAQRPDQLEETRPP 298
               P  P  P  P GP  P   +G    PG        G  S ET  A  P       PP
Sbjct: 1153 ASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRG-RSGETGPAGPPGNPGPPGPP 1211

Query: 299  GAARPG 304
            G   PG
Sbjct: 1212 GPPGPG 1217



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 79/316 (25%), Positives = 102/316 (32%), Gaps = 43/316 (13%)

Query: 78   PGRGRG-GLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPR 136
            PG+  G GL G       A     +    PPG        GAP  R   TG      PP 
Sbjct: 779  PGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGE-TG------PPG 831

Query: 137  LAAAHGLPASEA-PGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQ 195
             A   G P ++  PG + +      +   A A  P+G   AP       G T +      
Sbjct: 832  PAGFAGPPGADGQPGAKGEQGEAGQKGD-AGAPGPQGPSGAPGP----QGPTGVTG---- 882

Query: 196  PPPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDPGPIVGGRPENEDSPRFPDVPTRP- 254
              P  + G    PG      A  R      G  G+PGP     P  +D P+     + P 
Sbjct: 883  --PKGARGAQGPPGATGFPGAAGRVGP--PGSNGNPGPPGPPGPSGKDGPKGARGDSGPP 938

Query: 255  --------AGPSPFYCEGTEPGSQAWSARAGTASWETAAAQR-----PDQLEETRPPGAA 301
                     GP+    E  EPG    S   G    +  A QR     P Q  E   PG  
Sbjct: 939  GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLP 998

Query: 302  RPGARRLRSLASRLPRGGRWLDGGGSGRLTREPASLPNPIPPGSRVGAGGSERQNSKRIV 361
             P     +  A      G   D G  G +   P  L  P     R G+ G++    +   
Sbjct: 999  GPSGEPGKQGAP-----GASGDRGPPGPV--GPPGLTGPAGEPGREGSPGADGPPGRDGA 1051

Query: 362  YAGPGELRELVEVGEP 377
                G+  E   VG P
Sbjct: 1052 AGVKGDRGETGAVGAP 1067



 Score = 30.8 bits (68), Expect = 2.8
 Identities = 57/232 (24%), Positives = 75/232 (32%), Gaps = 32/232 (13%)

Query: 80  RGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAA 139
           RG  G PG+      +  P    +    GS     + GAP       G P  R PP    
Sbjct: 392 RGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAP-------GFPGPRGPPGPQG 444

Query: 140 AHGLPASEAPGLRPDSARTRLRLRLASARLPRGLP-PA-PAAGLWRAGCTRLRPLLLQP- 196
           A G    +     P  A  +        + P+G P PA P      AG    R    +P 
Sbjct: 445 ATGPLGPKGQTGEPGIAGFK------GEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPG 498

Query: 197 --PPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDPGPIVGGRPENEDSPRFPDVPTRP 254
              P+  PG   +PG          A      GE  P  + G +  N D       P RP
Sbjct: 499 GVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGD-------PGRP 551

Query: 255 AGPSPFYCEGTEPGSQAWSARAGTASWETAAAQRPDQLEETRPPGAARPGAR 306
             P         PG++  + R G A  +          E+ RP      GAR
Sbjct: 552 GEPG-------LPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGAR 596



 Score = 29.6 bits (65), Expect = 6.2
 Identities = 73/295 (24%), Positives = 95/295 (32%), Gaps = 43/295 (14%)

Query: 196 PPPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDPGPIVGGRPENEDSPRFPDVPTRPA 255
           P P   PG    PG+  +  A          G    G + G  P     PR P  P    
Sbjct: 161 PGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQG--PMGPMGPRGPPGPAGAP 218

Query: 256 GPSPFYCEGTEPGSQAWSARAGTAS--------WETAAAQRPDQLEETRPPG--AAR--P 303
           GP  F     EPG    S   G            +   A +P +  E  PPG   AR  P
Sbjct: 219 GPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFP 278

Query: 304 GARRLRSLASRLPRGGRWLDGG-------GSGRLTREPASLPNPIPPGSR---------- 346
           G   L  +     RG   LDG        G    +  P    +P P G R          
Sbjct: 279 GTPGLPGVKGH--RGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTG 336

Query: 347 -VGAGGSERQNSKRIVYAGPGELRELVEVGEPKSDPLLWEAGLDRAQ-VLGLRRRKTAHA 404
             GA G+   + +      PG +      G P +     EAG   A+   G +  +    
Sbjct: 337 PAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPG 396

Query: 405 LDAAPPPAGT--RAGTISSRISSGHWEPPILAFRIVGKQVYPPARPRLPAPPRGS 457
              +P PAG     GT     + G    P     I G   +P   PR P  P+G+
Sbjct: 397 TPGSPGPAGASGNPGTDGIPGAKGSAGAP----GIAGAPGFP--GPRGPPGPQGA 445


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 86/301 (28%), Positives = 101/301 (33%), Gaps = 54/301 (17%)

Query: 78  PGR-GRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPL-----QVGGAPRRRAHLTG--GP 129
           PG+ G  GLPGA  L     +      A PPG   P      Q    P     L G  GP
Sbjct: 545 PGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGP 604

Query: 130 PRR--RP-----PRLAAAHGL--PASEA--PGLRPDSARTRLRLRLASARLPRGLPPAPA 178
           P    +P     P  A A GL  P  E   PG R       L       + PRGLP  P 
Sbjct: 605 PGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGL-------QGPRGLPGTPG 657

Query: 179 AGLWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDPGPIVGGR 238
               +       P   Q P    PGL   PG         R      G +GD G +    
Sbjct: 658 TDGPKGASGPAGPPGAQGP----PGLQGMPG--------ERGAAGIAGPKGDRGDVGEKG 705

Query: 239 PE---NEDSPRFPDVPTRPAGPSPFYCEGTEPGSQAWSARAGTASWETAAAQRPDQLEET 295
           PE    +D  R    P  P GP+    E  E G    +  AG       A   P +  ET
Sbjct: 706 PEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAG-------ARGAPGERGET 758

Query: 296 RPPG----AARPGARRLRSLASRLPRGGRWLDGGGSGRLTREPASLPNPIPPGSRVGAGG 351
            PPG    A  PGA             G+  D G  G   + P+  P P  P    G  G
Sbjct: 759 GPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPG--PQGPSGAPGPQGPTGVTGPKG 816

Query: 352 S 352
           +
Sbjct: 817 A 817



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 77/323 (23%), Positives = 93/323 (28%), Gaps = 49/323 (15%)

Query: 81  GRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAP--RRRAHLTGGPPRRRPPRLA 138
           G  G PG         +P    ++ P G R P    G P     A   G    R PP   
Sbjct: 144 GPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQ 203

Query: 139 AAHGLPASE----------------------APGLRPDSARTRLRLRLASARLPRGLPPA 176
            A G P +                       APG++ +S              PRGL P 
Sbjct: 204 GARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPG-ENGSPGPMGPRGL-PG 261

Query: 177 PAAGLWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDPGPIVG 236
                  AG    R    QP P   PG     G              A G +G+ GP   
Sbjct: 262 ERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAG--------GPGFPGAPGAKGEAGPTGA 313

Query: 237 GRPENEDSPRFPDVPTRPAGPSPFYCEGTEPGSQAWSARAGTASWE--TAAAQRPDQLEE 294
             PE    PR    P  P  P P    G  PG+       G+A       A   P     
Sbjct: 314 RGPEGAQGPR--GEPGTPGSPGPAGASG-NPGTDGIPGAKGSAGAPGIAGAPGFPGPRGP 370

Query: 295 TRPPGAARPGARRLRSLASRLPRGGRWLDGGGSGRLTREPASLPNPIPPGSRVGAGGSER 354
             P GA  P            P+G     G    +  + P   P P  P    G  G E 
Sbjct: 371 PGPQGATGPLG----------PKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEG 420

Query: 355 QNSKRIVYAGPGELRELVEVGEP 377
           +   R    G G +    E G P
Sbjct: 421 KRGARGEPGGVGPIGPPGERGAP 443



 Score = 32.3 bits (72), Expect = 0.95
 Identities = 69/246 (28%), Positives = 83/246 (33%), Gaps = 33/246 (13%)

Query: 78   PG-RGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPR 136
            PG RG  G PG   L   + +P ++      G R P    G P       G P R   P 
Sbjct: 917  PGQRGERGFPG---LPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGP-AGEPGREGSP- 971

Query: 137  LAAAHGLPASE-APGLRPDSARTRLRLRLASARLPRGLP-PAPAAG-------------L 181
               A G P  + A G++ D   T   +    A  P G P PA   G             +
Sbjct: 972  --GADGPPGRDGAAGVKGDRGETGA-VGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPM 1028

Query: 182  WRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDPGPIVGGRPEN 241
              +G    R +     P    G A  PG E   + H R  T   G  G PGP      + 
Sbjct: 1029 GPSGPAGARGIQGPQGPRGDKGEAGEPG-ERGLKGH-RGFTGLQGLPGPPGP---SGDQG 1083

Query: 242  EDSPRFPDVPTRPAGP-SPFYCEGTE--PGSQAWSARAGTASWETAAAQRPDQLEETRPP 298
               P  P  P  P GP  P   +G    PG        G  S ET  A  P       PP
Sbjct: 1084 ASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRG-RSGETGPAGPPGNPGPPGPP 1142

Query: 299  GAARPG 304
            G   PG
Sbjct: 1143 GPPGPG 1148



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 79/316 (25%), Positives = 102/316 (32%), Gaps = 43/316 (13%)

Query: 78  PGRGRG-GLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPR 136
           PG+  G GL G       A     +    PPG        GAP  R   TG      PP 
Sbjct: 710 PGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGE-TG------PPG 762

Query: 137 LAAAHGLPASEA-PGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQ 195
            A   G P ++  PG + +      +   A A  P+G   AP       G T +      
Sbjct: 763 PAGFAGPPGADGQPGAKGEQGEAGQKGD-AGAPGPQGPSGAPGP----QGPTGVTG---- 813

Query: 196 PPPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDPGPIVGGRPENEDSPRFPDVPTRP- 254
             P  + G    PG      A  R      G  G+PGP     P  +D P+     + P 
Sbjct: 814 --PKGARGAQGPPGATGFPGAAGRVGP--PGSNGNPGPPGPPGPSGKDGPKGARGDSGPP 869

Query: 255 --------AGPSPFYCEGTEPGSQAWSARAGTASWETAAAQR-----PDQLEETRPPGAA 301
                    GP+    E  EPG    S   G    +  A QR     P Q  E   PG  
Sbjct: 870 GRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLP 929

Query: 302 RPGARRLRSLASRLPRGGRWLDGGGSGRLTREPASLPNPIPPGSRVGAGGSERQNSKRIV 361
            P     +  A      G   D G  G +   P  L  P     R G+ G++    +   
Sbjct: 930 GPSGEPGKQGAP-----GASGDRGPPGPV--GPPGLTGPAGEPGREGSPGADGPPGRDGA 982

Query: 362 YAGPGELRELVEVGEP 377
               G+  E   VG P
Sbjct: 983 AGVKGDRGETGAVGAP 998



 Score = 30.8 bits (68), Expect = 2.8
 Identities = 57/232 (24%), Positives = 75/232 (32%), Gaps = 32/232 (13%)

Query: 80  RGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAA 139
           RG  G PG+      +  P    +    GS     + GAP       G P  R PP    
Sbjct: 323 RGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAP-------GFPGPRGPPGPQG 375

Query: 140 AHGLPASEAPGLRPDSARTRLRLRLASARLPRGLP-PA-PAAGLWRAGCTRLRPLLLQP- 196
           A G    +     P  A  +        + P+G P PA P      AG    R    +P 
Sbjct: 376 ATGPLGPKGQTGEPGIAGFK------GEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPG 429

Query: 197 --PPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDPGPIVGGRPENEDSPRFPDVPTRP 254
              P+  PG   +PG          A      GE  P  + G +  N D       P RP
Sbjct: 430 GVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGD-------PGRP 482

Query: 255 AGPSPFYCEGTEPGSQAWSARAGTASWETAAAQRPDQLEETRPPGAARPGAR 306
             P         PG++  + R G A  +          E+ RP      GAR
Sbjct: 483 GEPG-------LPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGAR 527



 Score = 29.6 bits (65), Expect = 6.2
 Identities = 73/295 (24%), Positives = 95/295 (32%), Gaps = 43/295 (14%)

Query: 196 PPPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDPGPIVGGRPENEDSPRFPDVPTRPA 255
           P P   PG    PG+  +  A          G    G + G  P     PR P  P    
Sbjct: 92  PGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQG--PMGPMGPRGPPGPAGAP 149

Query: 256 GPSPFYCEGTEPGSQAWSARAGTAS--------WETAAAQRPDQLEETRPPG--AAR--P 303
           GP  F     EPG    S   G            +   A +P +  E  PPG   AR  P
Sbjct: 150 GPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFP 209

Query: 304 GARRLRSLASRLPRGGRWLDGG-------GSGRLTREPASLPNPIPPGSR---------- 346
           G   L  +     RG   LDG        G    +  P    +P P G R          
Sbjct: 210 GTPGLPGVKGH--RGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTG 267

Query: 347 -VGAGGSERQNSKRIVYAGPGELRELVEVGEPKSDPLLWEAGLDRAQ-VLGLRRRKTAHA 404
             GA G+   + +      PG +      G P +     EAG   A+   G +  +    
Sbjct: 268 PAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPG 327

Query: 405 LDAAPPPAGT--RAGTISSRISSGHWEPPILAFRIVGKQVYPPARPRLPAPPRGS 457
              +P PAG     GT     + G    P     I G   +P   PR P  P+G+
Sbjct: 328 TPGSPGPAGASGNPGTDGIPGAKGSAGAP----GIAGAPGFP--GPRGPPGPQGA 376


>gi|169206489 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 564

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 85/339 (25%), Positives = 114/339 (33%), Gaps = 71/339 (20%)

Query: 48  AHTRSPAQYSQTRLRRRRQGAVIVGRRRACPGRGRG----GLPG---------AAALGAG 94
           A  ++P      +LR+        G  R C G G      G P            A GA 
Sbjct: 178 ARRKTPLSLCPLKLRK--------GSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGAR 229

Query: 95  AQQPRRRRLAQPPGSRAPLQV-GGAPRRRAHLTGGPPRRR---PPRLAAAHGLPASEAPG 150
           AQ     + A P  +  P  V  G    RA   GG  R+R   P   + + G P  E   
Sbjct: 230 AQVRGSEKRACPGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGERSS 289

Query: 151 LRP--DSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLL------------QP 196
             P  D ++      L +AR+    PP+ AA  WR G  + +P +L            + 
Sbjct: 290 REPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEE 349

Query: 197 PPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDPGPIVGGRPENEDSPRFPDVPTRPAG 256
            P     L  + G EL ARA    H  + G    P P                   RP  
Sbjct: 350 DPRSGRALEPAQGSELWARA--ERHGGSSGARTLPTP----------------SRARPGK 391

Query: 257 PSPFYCEGTEPGSQAWSARAGTASWETAAAQRPDQLEETRPPGAARPGARRLRSLASRLP 316
           P+P    G+ P ++      G+   +   + R   +  T   G      RR     SR P
Sbjct: 392 PAP---RGSAPPARLRGGGGGSGLTQLVGSGRGSGV--THSVGTHALATRR----GSRAP 442

Query: 317 RGGRWLDGGGSGRLTREPASLPNPIPP-----GSRVGAG 350
           R    L G    R    PA    P  P     G R+GAG
Sbjct: 443 RPVGVLRGVPHFRPLSSPAPQSPPRSPSVRAFGPRLGAG 481



 Score = 33.5 bits (75), Expect = 0.43
 Identities = 59/236 (25%), Positives = 72/236 (30%), Gaps = 29/236 (12%)

Query: 11  SSAFMTWALGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTRLRRRRQGAVI 70
           S A   W LG         +  +R       E   +      PAQ S+   R  R G   
Sbjct: 317 SLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEEDPRSGRALEPAQGSELWARAERHGGSS 376

Query: 71  VGRRRACPGRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPP 130
             R    P R R G P               R + PP   A L+ GG       L G   
Sbjct: 377 GARTLPTPSRARPGKPAP-------------RGSAPP---ARLRGGGGGSGLTQLVGSGR 420

Query: 131 RRRPPRLAAAHGLP---ASEAPGLRPDSA-RTRLRLRLASARLPRGLPPAPAAGLW--RA 184
                     H L     S AP  RP    R     R  S+  P+  P +P+   +  R 
Sbjct: 421 GSGVTHSVGTHALATRRGSRAP--RPVGVLRGVPHFRPLSSPAPQSPPRSPSVRAFGPRL 478

Query: 185 GCTRLRPLLLQPPPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDPGPIVGGRPE 240
           G  RL      P     PG+A       H     R   C GG +    P  G R E
Sbjct: 479 GAGRL-SCPQAPRAAALPGIAVLAPSPAHDWGGQRCEGCGGGSQ----PFAGRRAE 529


>gi|169205942 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 564

 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 85/339 (25%), Positives = 114/339 (33%), Gaps = 71/339 (20%)

Query: 48  AHTRSPAQYSQTRLRRRRQGAVIVGRRRACPGRGRG----GLPG---------AAALGAG 94
           A  ++P      +LR+        G  R C G G      G P            A GA 
Sbjct: 178 ARRKTPLSLCPLKLRK--------GSSRRCQGLGSSWGGSGTPPPPRALWNRHGGAAGAR 229

Query: 95  AQQPRRRRLAQPPGSRAPLQV-GGAPRRRAHLTGGPPRRR---PPRLAAAHGLPASEAPG 150
           AQ     + A P  +  P  V  G    RA   GG  R+R   P   + + G P  E   
Sbjct: 230 AQVRGSEKRACPGSTLPPSSVLAGCVGTRARGHGGVQRQRFSAPSSHSTSGGRPTGERSS 289

Query: 151 LRP--DSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLL------------QP 196
             P  D ++      L +AR+    PP+ AA  WR G  + +P +L            + 
Sbjct: 290 REPLLDPSKAARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEE 349

Query: 197 PPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDPGPIVGGRPENEDSPRFPDVPTRPAG 256
            P     L  + G EL ARA    H  + G    P P                   RP  
Sbjct: 350 DPRSGRALEPAQGSELWARA--ERHGGSSGARTLPTP----------------SRARPGK 391

Query: 257 PSPFYCEGTEPGSQAWSARAGTASWETAAAQRPDQLEETRPPGAARPGARRLRSLASRLP 316
           P+P    G+ P ++      G+   +   + R   +  T   G      RR     SR P
Sbjct: 392 PAP---RGSAPPARLRGGGGGSGLTQLVGSGRGSGV--THSVGTHALATRR----GSRAP 442

Query: 317 RGGRWLDGGGSGRLTREPASLPNPIPP-----GSRVGAG 350
           R    L G    R    PA    P  P     G R+GAG
Sbjct: 443 RPVGVLRGVPHFRPLSSPAPQSPPRSPSVRAFGPRLGAG 481



 Score = 33.5 bits (75), Expect = 0.43
 Identities = 59/236 (25%), Positives = 72/236 (30%), Gaps = 29/236 (12%)

Query: 11  SSAFMTWALGPSAYSKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTRLRRRRQGAVI 70
           S A   W LG         +  +R       E   +      PAQ S+   R  R G   
Sbjct: 317 SLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEEDPRSGRALEPAQGSELWARAERHGGSS 376

Query: 71  VGRRRACPGRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPP 130
             R    P R R G P               R + PP   A L+ GG       L G   
Sbjct: 377 GARTLPTPSRARPGKPAP-------------RGSAPP---ARLRGGGGGSGLTQLVGSGR 420

Query: 131 RRRPPRLAAAHGLP---ASEAPGLRPDSA-RTRLRLRLASARLPRGLPPAPAAGLW--RA 184
                     H L     S AP  RP    R     R  S+  P+  P +P+   +  R 
Sbjct: 421 GSGVTHSVGTHALATRRGSRAP--RPVGVLRGVPHFRPLSSPAPQSPPRSPSVRAFGPRL 478

Query: 185 GCTRLRPLLLQPPPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDPGPIVGGRPE 240
           G  RL      P     PG+A       H     R   C GG +    P  G R E
Sbjct: 479 GAGRL-SCPQAPRAAALPGIAVLAPSPAHDWGGQRCEGCGGGSQ----PFAGRRAE 529


>gi|239757331 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 231

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 63/221 (28%), Positives = 84/221 (38%), Gaps = 27/221 (12%)

Query: 29  PRLPIRMTWGIPRESGIQKAHTRSPAQYSQTRLRRRRQGAVIVGRRRACPGRGRGGLPGA 88
           P  P+      PR S + ++  RSP   S++R R R +      RRR+   R        
Sbjct: 11  PSSPLSWPPPPPRASSLPRSLPRSPRLCSRSRSRSRSRS-----RRRSRSLRWLR----- 60

Query: 89  AALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPASEA 148
                     RR R    P S  P    G        +GG     P    +A   P   +
Sbjct: 61  ----------RRSRSRSRPFSSGPSGPSGPSSPGGPSSGGAS---PASEGSAMSPPPPRS 107

Query: 149 PGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLL---LQPPPMLSPGLA 205
             LR  S R R RLRL      R L    +    R+  +RLR  L    +     S  L+
Sbjct: 108 SSLRSRSRRARSRLRLLRRFRSRSLSLLRSLERLRSSLSRLRERLRRSRERERRRSRSLS 167

Query: 206 QSPGVELHARAHSRAHTCAGGGEGDPGPIVGGRPENEDSPR 246
           +S    L +R+ SR+ +  G GEG PG    GRP    SPR
Sbjct: 168 RSRLRSLRSRSRSRSRSLCGSGEG-PGLDEVGRPVWLGSPR 207


>gi|239751841 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 231

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 63/221 (28%), Positives = 84/221 (38%), Gaps = 27/221 (12%)

Query: 29  PRLPIRMTWGIPRESGIQKAHTRSPAQYSQTRLRRRRQGAVIVGRRRACPGRGRGGLPGA 88
           P  P+      PR S + ++  RSP   S++R R R +      RRR+   R        
Sbjct: 11  PSSPLSWPPPPPRASSLPRSLPRSPRLCSRSRSRSRSRS-----RRRSRSLRWLR----- 60

Query: 89  AALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPASEA 148
                     RR R    P S  P    G        +GG     P    +A   P   +
Sbjct: 61  ----------RRSRSRSRPFSSGPSGPSGPSSPGGPSSGGAS---PASEGSAMSPPPPRS 107

Query: 149 PGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLL---LQPPPMLSPGLA 205
             LR  S R R RLRL      R L    +    R+  +RLR  L    +     S  L+
Sbjct: 108 SSLRSRSRRARSRLRLLRRFRSRSLSLLRSLERLRSSLSRLRERLRRSRERERRRSRSLS 167

Query: 206 QSPGVELHARAHSRAHTCAGGGEGDPGPIVGGRPENEDSPR 246
           +S    L +R+ SR+ +  G GEG PG    GRP    SPR
Sbjct: 168 RSRLRSLRSRSRSRSRSLCGSGEG-PGLDEVGRPVWLGSPR 207


>gi|239746332 PREDICTED: hypothetical protein XP_002343733 [Homo
           sapiens]
          Length = 231

 Score = 46.2 bits (108), Expect = 6e-05
 Identities = 63/221 (28%), Positives = 84/221 (38%), Gaps = 27/221 (12%)

Query: 29  PRLPIRMTWGIPRESGIQKAHTRSPAQYSQTRLRRRRQGAVIVGRRRACPGRGRGGLPGA 88
           P  P+      PR S + ++  RSP   S++R R R +      RRR+   R        
Sbjct: 11  PSSPLSWPPPPPRASSLPRSLPRSPRLCSRSRSRSRSRS-----RRRSRSLRWLR----- 60

Query: 89  AALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPASEA 148
                     RR R    P S  P    G        +GG     P    +A   P   +
Sbjct: 61  ----------RRSRSRSRPFSSGPSGPSGPSSPGGPSSGGAS---PASEGSAMSPPPPRS 107

Query: 149 PGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLL---LQPPPMLSPGLA 205
             LR  S R R RLRL      R L    +    R+  +RLR  L    +     S  L+
Sbjct: 108 SSLRSRSRRARSRLRLLRRFRSRSLSLLRSLERLRSSLSRLRERLRRSRERERRRSRSLS 167

Query: 206 QSPGVELHARAHSRAHTCAGGGEGDPGPIVGGRPENEDSPR 246
           +S    L +R+ SR+ +  G GEG PG    GRP    SPR
Sbjct: 168 RSRLRSLRSRSRSRSRSLCGSGEG-PGLDEVGRPVWLGSPR 207


>gi|169168202 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 460

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 105/359 (29%), Positives = 125/359 (34%), Gaps = 58/359 (16%)

Query: 72  GRRRACPGRGRGGL--PGAAALGAGAQQ----PRRRRLAQPPGSRAPLQVGGAPRRRAHL 125
           GR RA P +G GG     AAA   G Q     PRR  L     SR     G  P      
Sbjct: 59  GRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLR----SRTDPAFGAGPLPLVSR 114

Query: 126 TGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAG 185
            G    R  P     + + AS  PG RPD       L L +   P G   AP       G
Sbjct: 115 LGHAGERGSPGAGDVNPVSASSPPG-RPDP------LLLTTFVFPPGKTSAPRPS---PG 164

Query: 186 CTRLRPLLLQPPPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDPGPIVGGRPENEDSP 245
             R RPL       L+PGL  SP ++      S   T      G        R  N  +P
Sbjct: 165 GRRGRPLGAARGTGLNPGL--SPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAP 222

Query: 246 RFPDVPTRPAGPSPFYCEGTEPGSQAWSARAGTASWETAAAQRPDQLEETRPPGAARPGA 305
           R        AG  P    G   G +A  A     +     ++ P       PPG +R  A
Sbjct: 223 RGSRRLRPDAGKFPEASGG--KGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRERA 280

Query: 306 -RRLRSLASRLPRGGRWLDGGGSGRLTRE---PA--SLPNPIPPGSRVGAGGSERQNSKR 359
              L   + ++PR G W       R  RE   PA  +L +P PP S   A    R     
Sbjct: 281 GAGLSRDSPQVPRSGSW------ARPCREQGHPAVLALQSPAPP-SLARAAARRR----- 328

Query: 360 IVYAGPGELRE--LVEVGEPKSDPLLWEAGLD------RAQVLGLRRRKTAHALDAAPP 410
               GPG   E   V +      PLL   G +      RA   GLR R     L AAPP
Sbjct: 329 ----GPGGATEPGFVTLAFRSRLPLLRSPGPEGTSDAARAPAPGLRDRD----LRAAPP 379



 Score = 37.0 bits (84), Expect = 0.039
 Identities = 70/268 (26%), Positives = 81/268 (30%), Gaps = 55/268 (20%)

Query: 75  RACPGRGRGGLPGAAALGAGAQQPRRRRLAQPPG----------SRAPLQVGGAPRRRAH 124
           R  PG GR G P  AA G G       RL +P G          SRA      AP RR +
Sbjct: 160 RPSPG-GRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRN 218

Query: 125 LTG--GPPRRRP-----PRLAAAHGL--------------PASEAPGLRPDSARTRLRLR 163
                G  R RP     P  +   G               P S  PGL            
Sbjct: 219 FGAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLNNGRGPRSRLPGLAGGVEPPGWSRE 278

Query: 164 LASARLPRGLPPAPAAGLWRAGCTR-----LRPLLLQPPPMLS--------PGLAQSPGV 210
            A A L R  P  P +G W   C       +  L    PP L+        PG A  PG 
Sbjct: 279 RAGAGLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGF 338

Query: 211 ELHARAHSRAHTCAGGGEGD------PGPIVGGRPENEDSPRFPDVPTRPAG---PSPFY 261
              A         + G EG       P P +  R      PR P    RP        F+
Sbjct: 339 VTLAFRSRLPLLRSPGPEGTSDAARAPAPGLRDRDLRAAPPR-PRPSQRPVSGLFKVKFF 397

Query: 262 CEGTEPGSQAWSARAGTASWETAAAQRP 289
              + PGS A      T +        P
Sbjct: 398 VPQSGPGSSACEVAVPTTAGRELLGSEP 425


>gi|169167967 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 460

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 105/359 (29%), Positives = 125/359 (34%), Gaps = 58/359 (16%)

Query: 72  GRRRACPGRGRGGL--PGAAALGAGAQQ----PRRRRLAQPPGSRAPLQVGGAPRRRAHL 125
           GR RA P +G GG     AAA   G Q     PRR  L     SR     G  P      
Sbjct: 59  GRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLR----SRTDPAFGAGPLPLVSR 114

Query: 126 TGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAG 185
            G    R  P     + + AS  PG RPD       L L +   P G   AP       G
Sbjct: 115 LGHAGERGSPGAGDVNPVSASSPPG-RPDP------LLLTTFVFPPGKTSAPRPS---PG 164

Query: 186 CTRLRPLLLQPPPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDPGPIVGGRPENEDSP 245
             R RPL       L+PGL  SP ++      S   T      G        R  N  +P
Sbjct: 165 GRRGRPLGAARGTGLNPGL--SPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAP 222

Query: 246 RFPDVPTRPAGPSPFYCEGTEPGSQAWSARAGTASWETAAAQRPDQLEETRPPGAARPGA 305
           R        AG  P    G   G +A  A     +     ++ P       PPG +R  A
Sbjct: 223 RGSRRLRPDAGKFPEASGG--KGQRAAGAERVLDNGRGPRSRLPGLAGGVEPPGWSRERA 280

Query: 306 -RRLRSLASRLPRGGRWLDGGGSGRLTRE---PA--SLPNPIPPGSRVGAGGSERQNSKR 359
              L   + ++PR G W       R  RE   PA  +L +P PP S   A    R     
Sbjct: 281 GAGLSRDSPQVPRSGSW------ARPCREQGHPAVLALQSPAPP-SLARAAARRR----- 328

Query: 360 IVYAGPGELRE--LVEVGEPKSDPLLWEAGLD------RAQVLGLRRRKTAHALDAAPP 410
               GPG   E   V +      PLL   G +      RA   GLR R     L AAPP
Sbjct: 329 ----GPGGATEPGFVTLAFRSRLPLLRSPGPEGTSDAARAPAPGLRDRD----LRAAPP 379



 Score = 37.0 bits (84), Expect = 0.039
 Identities = 70/268 (26%), Positives = 81/268 (30%), Gaps = 55/268 (20%)

Query: 75  RACPGRGRGGLPGAAALGAGAQQPRRRRLAQPPG----------SRAPLQVGGAPRRRAH 124
           R  PG GR G P  AA G G       RL +P G          SRA      AP RR +
Sbjct: 160 RPSPG-GRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRN 218

Query: 125 LTG--GPPRRRP-----PRLAAAHGL--------------PASEAPGLRPDSARTRLRLR 163
                G  R RP     P  +   G               P S  PGL            
Sbjct: 219 FGAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLDNGRGPRSRLPGLAGGVEPPGWSRE 278

Query: 164 LASARLPRGLPPAPAAGLWRAGCTR-----LRPLLLQPPPMLS--------PGLAQSPGV 210
            A A L R  P  P +G W   C       +  L    PP L+        PG A  PG 
Sbjct: 279 RAGAGLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGF 338

Query: 211 ELHARAHSRAHTCAGGGEGD------PGPIVGGRPENEDSPRFPDVPTRPAG---PSPFY 261
              A         + G EG       P P +  R      PR P    RP        F+
Sbjct: 339 VTLAFRSRLPLLRSPGPEGTSDAARAPAPGLRDRDLRAAPPR-PRPSQRPVSGLFKVKFF 397

Query: 262 CEGTEPGSQAWSARAGTASWETAAAQRP 289
              + PGS A      T +        P
Sbjct: 398 VPQSGPGSSACEVAVPTTAGRELLGSEP 425


>gi|169167681 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 460

 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 105/359 (29%), Positives = 125/359 (34%), Gaps = 58/359 (16%)

Query: 72  GRRRACPGRGRGGL--PGAAALGAGAQQ----PRRRRLAQPPGSRAPLQVGGAPRRRAHL 125
           GR RA P +G GG     AAA   G Q     PRR  L     SR     G  P      
Sbjct: 59  GRARAAPQQGDGGARRERAAAESLGTQSATLGPRRGGLR----SRTDPAFGAGPLPLVSR 114

Query: 126 TGGPPRRRPPRLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAG 185
            G    R  P     + + AS  PG RPD       L L +   P G   AP       G
Sbjct: 115 LGHAGERGSPGAGDVNPVSASSPPG-RPDP------LLLTTFVFPPGKTSAPRPS---PG 164

Query: 186 CTRLRPLLLQPPPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDPGPIVGGRPENEDSP 245
             R RPL       L+PGL  SP ++      S   T      G        R  N  +P
Sbjct: 165 GRRGRPLGAARGTGLNPGL--SPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRNFGAP 222

Query: 246 RFPDVPTRPAGPSPFYCEGTEPGSQAWSARAGTASWETAAAQRPDQLEETRPPGAARPGA 305
           R        AG  P    G   G +A  A     +     ++ P       PPG +R  A
Sbjct: 223 RGSRRLRPDAGKFPEASGG--KGQRAAGAERVLDNGRGPRSRLPGLAGGVEPPGWSRERA 280

Query: 306 -RRLRSLASRLPRGGRWLDGGGSGRLTRE---PA--SLPNPIPPGSRVGAGGSERQNSKR 359
              L   + ++PR G W       R  RE   PA  +L +P PP S   A    R     
Sbjct: 281 GAGLSRDSPQVPRSGSW------ARPCREQGHPAVLALQSPAPP-SLARAAARRR----- 328

Query: 360 IVYAGPGELRE--LVEVGEPKSDPLLWEAGLD------RAQVLGLRRRKTAHALDAAPP 410
               GPG   E   V +      PLL   G +      RA   GLR R     L AAPP
Sbjct: 329 ----GPGGATEPGFVTLAFRSRLPLLRSPGPEGTSDAARAPAPGLRDRD----LRAAPP 379



 Score = 37.0 bits (84), Expect = 0.039
 Identities = 70/268 (26%), Positives = 81/268 (30%), Gaps = 55/268 (20%)

Query: 75  RACPGRGRGGLPGAAALGAGAQQPRRRRLAQPPG----------SRAPLQVGGAPRRRAH 124
           R  PG GR G P  AA G G       RL +P G          SRA      AP RR +
Sbjct: 160 RPSPG-GRRGRPLGAARGTGLNPGLSPRLQEPRGHQSARRTDTASRAGWATRRAPSRRRN 218

Query: 125 LTG--GPPRRRP-----PRLAAAHGL--------------PASEAPGLRPDSARTRLRLR 163
                G  R RP     P  +   G               P S  PGL            
Sbjct: 219 FGAPRGSRRLRPDAGKFPEASGGKGQRAAGAERVLDNGRGPRSRLPGLAGGVEPPGWSRE 278

Query: 164 LASARLPRGLPPAPAAGLWRAGCTR-----LRPLLLQPPPMLS--------PGLAQSPGV 210
            A A L R  P  P +G W   C       +  L    PP L+        PG A  PG 
Sbjct: 279 RAGAGLSRDSPQVPRSGSWARPCREQGHPAVLALQSPAPPSLARAAARRRGPGGATEPGF 338

Query: 211 ELHARAHSRAHTCAGGGEGD------PGPIVGGRPENEDSPRFPDVPTRPAG---PSPFY 261
              A         + G EG       P P +  R      PR P    RP        F+
Sbjct: 339 VTLAFRSRLPLLRSPGPEGTSDAARAPAPGLRDRDLRAAPPR-PRPSQRPVSGLFKVKFF 397

Query: 262 CEGTEPGSQAWSARAGTASWETAAAQRP 289
              + PGS A      T +        P
Sbjct: 398 VPQSGPGSSACEVAVPTTAGRELLGSEP 425


>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
          Length = 1120

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 121/497 (24%), Positives = 169/497 (34%), Gaps = 70/497 (14%)

Query: 25   SKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTRLRRRRQGAVIVGRRRAC-PGRGRG 83
            S++ P L   M  G P    +  A  RSP+Q S   +  R +G+     + A  P  G  
Sbjct: 588  SELSPELQAAMAGGGPEPLPLPPA--RSPSQES---IGARSRGSGHSQEQPAPQPSGGDP 642

Query: 84   GLPGAAALGAGAQQPRRRRLAQP---------------PGSRAPLQVGGAPRRRAHLTGG 128
              P    L  G ++P +   + P               P S AP    GAP   ++L G 
Sbjct: 643  SPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGP 702

Query: 129  P--------PRRRPPRLAA---AHGLPASEAPG-----LRPDSARTRLRLRLASARLPRG 172
            P        P+RR   L+      G    EA G     L   +  TR   R A  R    
Sbjct: 703  PATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPS 762

Query: 173  LPPAPAAGLWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDPG 232
            + P PA G  R+    LR     PPP     L+   G          +    G  EG  G
Sbjct: 763  VTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDES---PGPKEGATG 819

Query: 233  PIVGGRPENEDS-PRFPDVPTRPAGPSPFYCEGTEPGSQAWSARAGTASWETAAAQRPDQ 291
            P    R  +E + P  P  P  PAGP+    E  EPG +      G++      A+  + 
Sbjct: 820  P--RRRTLSEPAGPSEPPGPPAPAGPAS-DTEEEEPGPEGTPPSRGSSGEGLPFAEEGNL 876

Query: 292  LEETRPPGAARP------------------GARRLRSLASRLPRGGRWLDGGGSGRLTRE 333
              + RP  A  P                    +R      R P     L  G +      
Sbjct: 877  TIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGP 936

Query: 334  PASLPNPIPPGSRVGAGGSERQNSKRIVYAGPGELRELVEVGEPKSDPLLWEAGLDRAQV 393
             A LP+P P  S   +   + + S       P  L     +  P   P     GL+ +  
Sbjct: 937  AAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPV--PPCPGPGLESSAA 994

Query: 394  LGLRRRKTAHALDAA---PPPAGTRAGTISSRISSGHWEPPILAFRIVGKQVYPPARPRL 450
                      A  AA    P AGT    +S   +   +  P LA R+ G +  PP RP  
Sbjct: 995  SRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAPRL-GPRPVPPPRPES 1053

Query: 451  PAP--PRGSQRRIYEAS 465
                 P  +Q+R+ + S
Sbjct: 1054 TGTVGPGQAQQRLEQTS 1070


>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
          Length = 1202

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 121/497 (24%), Positives = 169/497 (34%), Gaps = 70/497 (14%)

Query: 25   SKIPPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTRLRRRRQGAVIVGRRRAC-PGRGRG 83
            S++ P L   M  G P    +  A  RSP+Q S   +  R +G+     + A  P  G  
Sbjct: 670  SELSPELQAAMAGGGPEPLPLPPA--RSPSQES---IGARSRGSGHSQEQPAPQPSGGDP 724

Query: 84   GLPGAAALGAGAQQPRRRRLAQP---------------PGSRAPLQVGGAPRRRAHLTGG 128
              P    L  G ++P +   + P               P S AP    GAP   ++L G 
Sbjct: 725  SPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGP 784

Query: 129  P--------PRRRPPRLAA---AHGLPASEAPG-----LRPDSARTRLRLRLASARLPRG 172
            P        P+RR   L+      G    EA G     L   +  TR   R A  R    
Sbjct: 785  PATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPS 844

Query: 173  LPPAPAAGLWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDPG 232
            + P PA G  R+    LR     PPP     L+   G          +    G  EG  G
Sbjct: 845  VTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDES---PGPKEGATG 901

Query: 233  PIVGGRPENEDS-PRFPDVPTRPAGPSPFYCEGTEPGSQAWSARAGTASWETAAAQRPDQ 291
            P    R  +E + P  P  P  PAGP+    E  EPG +      G++      A+  + 
Sbjct: 902  P--RRRTLSEPAGPSEPPGPPAPAGPAS-DTEEEEPGPEGTPPSRGSSGEGLPFAEEGNL 958

Query: 292  LEETRPPGAARP------------------GARRLRSLASRLPRGGRWLDGGGSGRLTRE 333
              + RP  A  P                    +R      R P     L  G +      
Sbjct: 959  TIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGP 1018

Query: 334  PASLPNPIPPGSRVGAGGSERQNSKRIVYAGPGELRELVEVGEPKSDPLLWEAGLDRAQV 393
             A LP+P P  S   +   + + S       P  L     +  P   P     GL+ +  
Sbjct: 1019 AAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPV--PPCPGPGLESSAA 1076

Query: 394  LGLRRRKTAHALDAA---PPPAGTRAGTISSRISSGHWEPPILAFRIVGKQVYPPARPRL 450
                      A  AA    P AGT    +S   +   +  P LA R+ G +  PP RP  
Sbjct: 1077 SRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAPRL-GPRPVPPPRPES 1135

Query: 451  PAP--PRGSQRRIYEAS 465
                 P  +Q+R+ + S
Sbjct: 1136 TGTVGPGQAQQRLEQTS 1152


>gi|23510413 sorting nexin 26 [Homo sapiens]
          Length = 1126

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 77/282 (27%), Positives = 102/282 (36%), Gaps = 34/282 (12%)

Query: 90  ALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGG------PPRRRPPRLAAAHGL 143
           ALG G   PR++ L    G+RAP Q  G+      L           +     L  A G 
Sbjct: 596 ALGRGPSVPRKKPLPWLGGTRAPPQPSGSRPDTVTLRSAKSEESLSSQASGAELLGAGGA 655

Query: 144 PASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLR----PL------L 193
           PAS  P       R+ LR  L    L RG          +  C++LR    PL       
Sbjct: 656 PASATPTPALSPGRS-LRPHLIPLLL-RGAEAPLTDACQQEMCSKLRGAQGPLGPDMESP 713

Query: 194 LQPPP--MLSPGLAQSPGVELHAR--AHSRAHTCAGGGEGDPGPIVGGRPENEDSPRFPD 249
           L PPP  +L PG A  P  +  AR  A + A       E       GG P    SP F  
Sbjct: 714 LPPPPLSLLRPGGAPPPPPKNPARLMALALAERAQQVAEQQSQQECGGTPPASQSP-FHR 772

Query: 250 VPTRPAGPSPFYCEGTEPGSQ------AWSARAGTASWETAAAQRPDQLEETRPPGAARP 303
             +   G  P    G+ P         AW    G   +          L   RP G +R 
Sbjct: 773 SLSLEVGGEPLGTSGSGPPPNSLAHPGAWV--PGPPPYLPRQQSDGSLLRSQRPMGTSRR 830

Query: 304 GARRLRSLASRLPRGGRWLDGGGSGRLTREPASLPNPIP-PG 344
           G R    ++++L  GG   D   +    + P S+P+ +P PG
Sbjct: 831 GLRGPAQVSAQLRAGGGGRDAPEAA--AQSPCSVPSQVPTPG 870



 Score = 34.3 bits (77), Expect = 0.25
 Identities = 70/273 (25%), Positives = 84/273 (30%), Gaps = 67/273 (24%)

Query: 86   PGAAALGAGAQQPRR-----RRLAQPPGSRAPLQVG-----------GAPRRRAHLTGGP 129
            PG   LG  + QP       R    PP   APL  G           G+P      +  P
Sbjct: 889  PGLYPLGPPSFQPSSPAPVWRSSLGPP---APLDRGENLYYEIGASEGSPYSGPTRSWSP 945

Query: 130  PRRRPP-RLAAAHGLPASEAPGLR-PDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCT 187
             R  PP RL A++G+     P  R PD         L+    P   PP    G       
Sbjct: 946  FRSMPPDRLNASYGMLGQSPPLHRSPD-------FLLSYPPAPSCFPP-DHLGYSAPQHP 997

Query: 188  RLRPLLLQPPPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDPGPIVGGRPENEDSPRF 247
              RP    PP  L   LA  P     A + S +         DPGP V   P+ + +P  
Sbjct: 998  ARRPT---PPEPLYVNLALGPRGPSPASSSSSSPPAHPRSRSDPGPPVPRLPQKQRAPWG 1054

Query: 248  PDVPTRPAGPSPFYCEGTEPGSQAWSARAGTASWETAAAQRPDQLEETRPPGAARPGARR 307
            P  P R  GP              W                P  L    PP   R G   
Sbjct: 1055 PRTPHRVPGP--------------W------------GPPEPLLLYRAAPPAYGRGG--- 1085

Query: 308  LRSLASRLPRGGRWLDGGGSGRLTREPASLPNP 340
                   L RG  + +GG  G     P   P P
Sbjct: 1086 ------ELHRGSLYRNGGQRGEGAGPPPPYPTP 1112


>gi|239757110 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 192

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 54/186 (29%), Positives = 67/186 (36%), Gaps = 15/186 (8%)

Query: 103 LAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPASEA--PGLRPDSARTRL 160
           LA+   +  P   G A  RRAH +G P + R  R  AA GLP      P     S+    
Sbjct: 3   LAEESAAGHPTPGGPASARRAH-SGRPHQAR--RHPAAWGLPVRRPSHPPRPTTSSWANG 59

Query: 161 RLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQPPPMLSPGLAQSPGVELHARAHSRA 220
             R   A L   LP  P  GL   GC R        P +  P      G + H R     
Sbjct: 60  SNRQHPAELSVQLPANPPPGL-NQGCIRAASAPRWVPTLTVPQATLPGGSQGHRR----- 113

Query: 221 HTCAGGGEGDPGPIVGGRPENEDSP--RFPDVPTRPAGPSPFYCEGTEPGSQAWSARAGT 278
             C G GEG     V  +P    +P      +   P  P P +      G++A    A T
Sbjct: 114 --CRGEGEGQRRGCVEKQPRPTPTPACELTGLAPAPPTPPPAWWRWARTGTRAMGGAAST 171

Query: 279 ASWETA 284
            S  TA
Sbjct: 172 GSAPTA 177


>gi|239751535 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 255

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 51/157 (32%), Positives = 58/157 (36%), Gaps = 30/157 (19%)

Query: 28  PPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTRLRRRRQGAVIVGRRRACPGRGRGGLPG 87
           PPRLP   T               S +  +QTRLRRR   A+   R   CP R   G   
Sbjct: 115 PPRLPRPFT---------------SASFSNQTRLRRRSASALPAPR--LCPQRASPGCSS 157

Query: 88  AAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPASE 147
               G G     R R      + A  Q  G  R R+    G    R   LA A  LP   
Sbjct: 158 PGVRGPGGGASPRARGGNAAAALAARQAAGGGRSRSAFVAG----RDAALACAQ-LPRRP 212

Query: 148 APGLRPDSARTRLRLRLAS----ARLPRGLPPAPAAG 180
               R   AR  +R RL +    A  PRG P APA G
Sbjct: 213 ----RGAGARRGMRRRLGAGERPAPRPRGPPRAPARG 245


>gi|239746046 PREDICTED: hypothetical protein XP_002343643 [Homo
           sapiens]
          Length = 255

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 51/157 (32%), Positives = 58/157 (36%), Gaps = 30/157 (19%)

Query: 28  PPRLPIRMTWGIPRESGIQKAHTRSPAQYSQTRLRRRRQGAVIVGRRRACPGRGRGGLPG 87
           PPRLP   T               S +  +QTRLRRR   A+   R   CP R   G   
Sbjct: 115 PPRLPRPFT---------------SASFSNQTRLRRRSASALPAPR--LCPQRASPGCSS 157

Query: 88  AAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPPRLAAAHGLPASE 147
               G G     R R      + A  Q  G  R R+    G    R   LA A  LP   
Sbjct: 158 PGVRGPGGGASPRARGGNAAAALAARQAAGGGRSRSAFVAG----RDAALACAQ-LPRRP 212

Query: 148 APGLRPDSARTRLRLRLAS----ARLPRGLPPAPAAG 180
               R   AR  +R RL +    A  PRG P APA G
Sbjct: 213 ----RGAGARRGMRRRLGAGERPAPRPRGPPRAPARG 245


>gi|169162152 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 520

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 84/308 (27%), Positives = 100/308 (32%), Gaps = 61/308 (19%)

Query: 76  ACPGRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPP 135
           A   RGRGG    AA G+  Q P  R L     S A       P  +  L        PP
Sbjct: 236 AAGSRGRGGAERPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSA----SPP 291

Query: 136 RLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQ 195
           RLAA   L  S AP L P   R R R   + A     LP + + G    G  R R     
Sbjct: 292 RLAAP--LAGSRAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRR----- 344

Query: 196 PPPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDP-GPIVGGRPENEDSPR-------F 247
                        G E   R   R   CA G    P GP   GR     + R        
Sbjct: 345 -------------GGE-ERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRKRGGG 390

Query: 248 PDVPTRPAGPSPFYCEGTEPGSQAWSA--RAGTASWETAAAQR-----------PDQLEE 294
           P V  R          G  P ++  S   R   A+W+  A  R           P    E
Sbjct: 391 PGVSPREGAQGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGPRLSAPSAEAE 450

Query: 295 TRPPG--AARPGARRLRSLASRLPRGGR-----------WLD-GGGSGRLTREPASLP-N 339
             P G  A+ P    L S  ++ P  GR           +LD   G G +   P+  P N
Sbjct: 451 EVPGGHTASNPTYEPLSSRRTKAPSEGRDSPSSPATSTHYLDRESGLGSVNSHPSRSPYN 510

Query: 340 PIPPGSRV 347
             PP   V
Sbjct: 511 WSPPSPSV 518



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 43/153 (28%), Positives = 50/153 (32%), Gaps = 25/153 (16%)

Query: 19  LGPSAYSKIPPRLPIRMTWG-----IPRESGIQKAHTRSPAQYSQTRLRRRRQGAVIVGR 73
           L P   S  PPRL   +         P     ++   RSPA +     R   +G  +VG 
Sbjct: 281 LQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGA 340

Query: 74  RRACPG---RGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRA----HLT 126
           RR   G   R RG   G A             L  PP    P   G A  RRA       
Sbjct: 341 RRRRGGEERRVRGRRQGCA-------------LGSPPIPAGPAAPGRAGERRAARQWRKR 387

Query: 127 GGPPRRRPPRLAAAHGLPASEAPGLRPDSARTR 159
           GG P   P   A   G+     P  R  S   R
Sbjct: 388 GGGPGVSPREGAQGEGVRGGVTPRARGSSTCLR 420


>gi|239746104 PREDICTED: hypothetical protein XP_002344198 [Homo
           sapiens]
          Length = 398

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 63/234 (26%), Positives = 85/234 (36%), Gaps = 44/234 (18%)

Query: 233 PIVGGRPENEDSPR--------FPDVPTRPAGPSPFYCEGTEPGSQAWSARAGTASWETA 284
           P+   R EN D+ R        F  +   P   SP       PG  + +   G       
Sbjct: 3   PVGRSRSENADTARLFGTAVYTFEVLGALPPDRSPTPRSRVSPGVTSLAVGPGN------ 56

Query: 285 AAQRPDQLEETRPP--GAARPGARRLRSLASRLPRGGRWLDGGGSGRLTREPASLPNPIP 342
               P + + +  P  G   PG ++LR   +RLPR  +  +  G GR  R+PA  P  + 
Sbjct: 57  ----PTRCQRSGVPYEGPGAPGGQQLRKSRARLPRTRQGREDAGVGRRNRDPAE-PGSLR 111

Query: 343 PGSRVGAGGSERQNSKRIVYAGPG-ELRELVEVGEPKSDPLLWEAGLDRAQVLGLRRRKT 401
           P S    G   R    R+  A PG +LR     GEPK+ P        R+   G  R   
Sbjct: 112 PTS---LGFPARAGQGRVQGAAPGRKLR-----GEPKTPP-------GRSGPSGGVRSGA 156

Query: 402 AHALDAAPPPAGTRAGTISSRISSGHWEPPILAFRIVGKQVYP--PARPRLPAP 453
            H   AA    G         + +G   P  L     G  + P  P RP  P P
Sbjct: 157 GHRAAAAEHQLGA-----GFSVRNGPGPPARLPPAPPGPLLRPARPPRPYFPRP 205


>gi|169161145 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 520

 Score = 43.5 bits (101), Expect = 4e-04
 Identities = 84/308 (27%), Positives = 100/308 (32%), Gaps = 61/308 (19%)

Query: 76  ACPGRGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRAHLTGGPPRRRPP 135
           A   RGRGG    AA G+  Q P  R L     S A       P  +  L        PP
Sbjct: 236 AAGSRGRGGAERPAARGSAQQPPLARLLLASAVSLAASLARSPPPLQPRLGSA----SPP 291

Query: 136 RLAAAHGLPASEAPGLRPDSARTRLRLRLASARLPRGLPPAPAAGLWRAGCTRLRPLLLQ 195
           RLAA   L  S AP L P   R R R   + A     LP + + G    G  R R     
Sbjct: 292 RLAAP--LAGSRAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGARRRR----- 344

Query: 196 PPPMLSPGLAQSPGVELHARAHSRAHTCAGGGEGDP-GPIVGGRPENEDSPR-------F 247
                        G E   R   R   CA G    P GP   GR     + R        
Sbjct: 345 -------------GGE-ERRVRGRRQGCALGSPPIPAGPAAPGRAGERRAARQWRKRGGG 390

Query: 248 PDVPTRPAGPSPFYCEGTEPGSQAWSA--RAGTASWETAAAQR-----------PDQLEE 294
           P V  R          G  P ++  S   R   A+W+  A  R           P    E
Sbjct: 391 PGVSPREGAQGEGVRGGVTPRARGSSTCLRPSPATWQGGAPYRAIFAAGPRLSAPSAEAE 450

Query: 295 TRPPG--AARPGARRLRSLASRLPRGGR-----------WLD-GGGSGRLTREPASLP-N 339
             P G  A+ P    L S  ++ P  GR           +LD   G G +   P+  P N
Sbjct: 451 EVPGGHTASNPTYEPLSSRRTKAPSEGRDSPSSPATSTHYLDRESGLGSVNSHPSRSPYN 510

Query: 340 PIPPGSRV 347
             PP   V
Sbjct: 511 WSPPSPSV 518



 Score = 32.0 bits (71), Expect = 1.2
 Identities = 43/153 (28%), Positives = 50/153 (32%), Gaps = 25/153 (16%)

Query: 19  LGPSAYSKIPPRLPIRMTWG-----IPRESGIQKAHTRSPAQYSQTRLRRRRQGAVIVGR 73
           L P   S  PPRL   +         P     ++   RSPA +     R   +G  +VG 
Sbjct: 281 LQPRLGSASPPRLAAPLAGSRAPSLSPFPRRCRRRAERSPAGHGLPLPRSLSRGGEVVGA 340

Query: 74  RRACPG---RGRGGLPGAAALGAGAQQPRRRRLAQPPGSRAPLQVGGAPRRRA----HLT 126
           RR   G   R RG   G A             L  PP    P   G A  RRA       
Sbjct: 341 RRRRGGEERRVRGRRQGCA-------------LGSPPIPAGPAAPGRAGERRAARQWRKR 387

Query: 127 GGPPRRRPPRLAAAHGLPASEAPGLRPDSARTR 159
           GG P   P   A   G+     P  R  S   R
Sbjct: 388 GGGPGVSPREGAQGEGVRGGVTPRARGSSTCLR 420


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.136    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,597,079
Number of Sequences: 37866
Number of extensions: 1793454
Number of successful extensions: 11227
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 61
Number of HSP's successfully gapped in prelim test: 995
Number of HSP's that attempted gapping in prelim test: 9277
Number of HSP's gapped (non-prelim): 2763
length of query: 470
length of database: 18,247,518
effective HSP length: 106
effective length of query: 364
effective length of database: 14,233,722
effective search space: 5181074808
effective search space used: 5181074808
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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