Guide to the Human Genome
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Name: HCN2 Sequence: fasta or formatted (889aa) NCBI GI: 156071470
Description:

hyperpolarization activated cyclic nucleotide-gated potassium channel 2

Referenced in:

Potassium Channels

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.6         85           3
 C cysteine            1.6         14           1
 D aspartate           3.9         35           1
 E glutamate           4.9         44           2
 F phenylalanine       4.5         40           2
 G glycine             8.2         73           4
 H histidine           1.7         15           1
 I isoleucine          4.9         44           3
 K lysine              3.5         31           3
 L leucine             8.2         73           3
 M methionine          3.1         28           2
 N asparagine          2.7         24           2
 P proline            11.8        105           7
 Q glutamine           4.0         36           3
 R arginine            7.2         64           2
 S serine              7.8         69           3
 T threonine           3.6         32           2
 V valine              4.9         44           2
 W tryptophan          1.0          9           1
 Y tyrosine            2.7         24           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   hyperpolarization activated cyclic nucleotide-gated... 
HCN4                  0.581   hyperpolarization activated cyclic nucleotide-gated p...
HCN1                  0.543   hyperpolarization activated cyclic nucleotide-gated...
HCN3                  0.492   hyperpolarization activated cyclic nucleotide-gated ...
CNGA3                 0.087   cyclic nucleotide gated channel alpha 3 isoform 2 [...
KCNH6                 0.086   potassium voltage-gated channel, subfamily H, member...
CNGA3                 0.086   cyclic nucleotide gated channel alpha 3 isoform 1 [Ho...
KCNH7                 0.082   potassium voltage-gated channel, subfamily H, member...
KCNH2                 0.082   voltage-gated potassium channel, subfamily H, member...
KCNH2                 0.082   voltage-gated potassium channel, subfamily H, member ...
KCNH1                 0.082   potassium voltage-gated channel, subfamily H, member ...
KCNH4                 0.080   potassium voltage-gated channel, subfamily H, member ...
CNGA4                 0.080   cyclic nucleotide gated channel alpha 4 
KCNH5                 0.080   potassium voltage-gated channel, subfamily H, member...
KCNH5                 0.080   potassium voltage-gated channel, subfamily H, member...
KCNH6                 0.080   potassium voltage-gated channel, subfamily H, member...
CNGA2                 0.079   cyclic nucleotide gated channel alpha 2 
CNGA1                 0.079   cyclic nucleotide gated channel alpha 1 isoform 1 [...
CNGA1                 0.079   cyclic nucleotide gated channel alpha 1 isoform 2 [H...
KCNH1                 0.078   potassium voltage-gated channel, subfamily H, member...
KCNH8                 0.075   potassium voltage-gated channel, subfamily H, member...
CNGB1                 0.074   cyclic nucleotide gated channel beta 1 isoform a [H...
KCNH3                 0.072   potassium voltage-gated channel, subfamily H (eag-re...
KCNH2                 0.070   voltage-gated potassium channel, subfamily H, member...
KCNH5                 0.069   potassium voltage-gated channel, subfamily H, member...
CNGB3                 0.061   cyclic nucleotide gated channel beta 3 
KCNH7                 0.060   potassium voltage-gated channel, subfamily H, member...
SFPQ                  0.031   splicing factor proline/glutamine rich (polypyrimidin...
PRB1                  0.026   proline-rich protein BstNI subfamily 1 isoform 1 pre...
FOXG1                 0.026   forkhead box G1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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