Search of human proteins with 239742549

Search of human proteins with 239742549

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239742549 PREDICTED: hypothetical protein LOC345645 [Homo
sapiens]
         (415 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|169167838 PREDICTED: similar to hCG2002932 [Homo sapiens]          817   0.0  
gi|239748566 PREDICTED: similar to hCG2002932 [Homo sapiens]          817   0.0  
gi|239742549 PREDICTED: hypothetical protein LOC345645 [Homo sap...   817   0.0  
gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]            669   0.0  
gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit ...   317   1e-86
gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens]   317   1e-86
gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo sapi...   309   3e-84
gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens]            281   6e-76
gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens]            280   1e-75
gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens]             252   4e-67
gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens]           241   7e-64
gi|157671927 spermatogenesis associated 5 [Homo sapiens]              168   7e-42
gi|6005942 valosin-containing protein [Homo sapiens]                  156   3e-38
gi|5802970 AFG3 ATPase family gene 3-like 2 [Homo sapiens]            151   1e-36
gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens]   145   7e-35
gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens]       144   2e-34
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]     138   1e-32
gi|4505725 peroxin1 [Homo sapiens]                                    131   1e-30
gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]                 129   5e-30
gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]                 129   5e-30
gi|4507173 spastic paraplegia 7 isoform 1 [Homo sapiens]              125   9e-29
gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]           114   1e-25
gi|21327685 YME1-like 1 isoform 1 [Homo sapiens]                      113   3e-25
gi|7657689 YME1-like 1 isoform 3 [Homo sapiens]                       113   3e-25
gi|113426932 PREDICTED: similar to N-ethylmaleimide-sensitive fa...   112   6e-25
gi|5901990 katanin p60 subunit A 1 [Homo sapiens]                     112   6e-25
gi|156564401 vesicle-fusing ATPase [Homo sapiens]                     112   8e-25
gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens]               108   1e-23
gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens]               108   1e-23
gi|226371754 katanin p60 subunit A-like 2 [Homo sapiens]              105   6e-23

>gi|169167838 PREDICTED: similar to hCG2002932 [Homo sapiens]
          Length = 415

 Score =  817 bits (2110), Expect = 0.0
 Identities = 415/415 (100%), Positives = 415/415 (100%)

Query: 1   MIVEVEELPAVAAQVAKTRVAEKEEKTKGQDVASKLPLVTLHTQCRLKLLKLERIKDYLL 60
           MIVEVEELPAVAAQVAKTRVAEKEEKTKGQDVASKLPLVTLHTQCRLKLLKLERIKDYLL
Sbjct: 1   MIVEVEELPAVAAQVAKTRVAEKEEKTKGQDVASKLPLVTLHTQCRLKLLKLERIKDYLL 60

Query: 61  MVEEFIRNQEQIKLLEEKQEEGRSKVDDLRGTPMSVGNLEEIIDDNHAIVSTSVGSEHYD 120
           MVEEFIRNQEQIKLLEEKQEEGRSKVDDLRGTPMSVGNLEEIIDDNHAIVSTSVGSEHYD
Sbjct: 61  MVEEFIRNQEQIKLLEEKQEEGRSKVDDLRGTPMSVGNLEEIIDDNHAIVSTSVGSEHYD 120

Query: 121 SIISFVEKDLLEPGCSILLRHKVHAVIGVLMDDTGPLVTMMKVEKAPQETYVNTGGLDNQ 180
           SIISFVEKDLLEPGCSILLRHKVHAVIGVLMDDTGPLVTMMKVEKAPQETYVNTGGLDNQ
Sbjct: 121 SIISFVEKDLLEPGCSILLRHKVHAVIGVLMDDTGPLVTMMKVEKAPQETYVNTGGLDNQ 180

Query: 181 IQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTATFLRVVGSELIQKYLGDGPKLV 240
           IQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTATFLRVVGSELIQKYLGDGPKLV
Sbjct: 181 IQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTATFLRVVGSELIQKYLGDGPKLV 240

Query: 241 RQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGEREIQQTMLELELLNQLGGFDSREDV 300
           RQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGEREIQQTMLELELLNQLGGFDSREDV
Sbjct: 241 RQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGEREIQQTMLELELLNQLGGFDSREDV 300

Query: 301 KVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKTKKHIFQIHTSRMTLANDVTLDDLIM 360
           KVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKTKKHIFQIHTSRMTLANDVTLDDLIM
Sbjct: 301 KVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKTKKHIFQIHTSRMTLANDVTLDDLIM 360

Query: 361 AKDDFSGADIKAICTEAGLMALREHRMKATNEDFKKSIESVLYKKHEGIPEGLYL 415
           AKDDFSGADIKAICTEAGLMALREHRMKATNEDFKKSIESVLYKKHEGIPEGLYL
Sbjct: 361 AKDDFSGADIKAICTEAGLMALREHRMKATNEDFKKSIESVLYKKHEGIPEGLYL 415


>gi|239748566 PREDICTED: similar to hCG2002932 [Homo sapiens]
          Length = 415

 Score =  817 bits (2110), Expect = 0.0
 Identities = 415/415 (100%), Positives = 415/415 (100%)

Query: 1   MIVEVEELPAVAAQVAKTRVAEKEEKTKGQDVASKLPLVTLHTQCRLKLLKLERIKDYLL 60
           MIVEVEELPAVAAQVAKTRVAEKEEKTKGQDVASKLPLVTLHTQCRLKLLKLERIKDYLL
Sbjct: 1   MIVEVEELPAVAAQVAKTRVAEKEEKTKGQDVASKLPLVTLHTQCRLKLLKLERIKDYLL 60

Query: 61  MVEEFIRNQEQIKLLEEKQEEGRSKVDDLRGTPMSVGNLEEIIDDNHAIVSTSVGSEHYD 120
           MVEEFIRNQEQIKLLEEKQEEGRSKVDDLRGTPMSVGNLEEIIDDNHAIVSTSVGSEHYD
Sbjct: 61  MVEEFIRNQEQIKLLEEKQEEGRSKVDDLRGTPMSVGNLEEIIDDNHAIVSTSVGSEHYD 120

Query: 121 SIISFVEKDLLEPGCSILLRHKVHAVIGVLMDDTGPLVTMMKVEKAPQETYVNTGGLDNQ 180
           SIISFVEKDLLEPGCSILLRHKVHAVIGVLMDDTGPLVTMMKVEKAPQETYVNTGGLDNQ
Sbjct: 121 SIISFVEKDLLEPGCSILLRHKVHAVIGVLMDDTGPLVTMMKVEKAPQETYVNTGGLDNQ 180

Query: 181 IQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTATFLRVVGSELIQKYLGDGPKLV 240
           IQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTATFLRVVGSELIQKYLGDGPKLV
Sbjct: 181 IQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTATFLRVVGSELIQKYLGDGPKLV 240

Query: 241 RQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGEREIQQTMLELELLNQLGGFDSREDV 300
           RQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGEREIQQTMLELELLNQLGGFDSREDV
Sbjct: 241 RQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGEREIQQTMLELELLNQLGGFDSREDV 300

Query: 301 KVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKTKKHIFQIHTSRMTLANDVTLDDLIM 360
           KVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKTKKHIFQIHTSRMTLANDVTLDDLIM
Sbjct: 301 KVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKTKKHIFQIHTSRMTLANDVTLDDLIM 360

Query: 361 AKDDFSGADIKAICTEAGLMALREHRMKATNEDFKKSIESVLYKKHEGIPEGLYL 415
           AKDDFSGADIKAICTEAGLMALREHRMKATNEDFKKSIESVLYKKHEGIPEGLYL
Sbjct: 361 AKDDFSGADIKAICTEAGLMALREHRMKATNEDFKKSIESVLYKKHEGIPEGLYL 415


>gi|239742549 PREDICTED: hypothetical protein LOC345645 [Homo
           sapiens]
          Length = 415

 Score =  817 bits (2110), Expect = 0.0
 Identities = 415/415 (100%), Positives = 415/415 (100%)

Query: 1   MIVEVEELPAVAAQVAKTRVAEKEEKTKGQDVASKLPLVTLHTQCRLKLLKLERIKDYLL 60
           MIVEVEELPAVAAQVAKTRVAEKEEKTKGQDVASKLPLVTLHTQCRLKLLKLERIKDYLL
Sbjct: 1   MIVEVEELPAVAAQVAKTRVAEKEEKTKGQDVASKLPLVTLHTQCRLKLLKLERIKDYLL 60

Query: 61  MVEEFIRNQEQIKLLEEKQEEGRSKVDDLRGTPMSVGNLEEIIDDNHAIVSTSVGSEHYD 120
           MVEEFIRNQEQIKLLEEKQEEGRSKVDDLRGTPMSVGNLEEIIDDNHAIVSTSVGSEHYD
Sbjct: 61  MVEEFIRNQEQIKLLEEKQEEGRSKVDDLRGTPMSVGNLEEIIDDNHAIVSTSVGSEHYD 120

Query: 121 SIISFVEKDLLEPGCSILLRHKVHAVIGVLMDDTGPLVTMMKVEKAPQETYVNTGGLDNQ 180
           SIISFVEKDLLEPGCSILLRHKVHAVIGVLMDDTGPLVTMMKVEKAPQETYVNTGGLDNQ
Sbjct: 121 SIISFVEKDLLEPGCSILLRHKVHAVIGVLMDDTGPLVTMMKVEKAPQETYVNTGGLDNQ 180

Query: 181 IQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTATFLRVVGSELIQKYLGDGPKLV 240
           IQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTATFLRVVGSELIQKYLGDGPKLV
Sbjct: 181 IQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTATFLRVVGSELIQKYLGDGPKLV 240

Query: 241 RQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGEREIQQTMLELELLNQLGGFDSREDV 300
           RQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGEREIQQTMLELELLNQLGGFDSREDV
Sbjct: 241 RQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGEREIQQTMLELELLNQLGGFDSREDV 300

Query: 301 KVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKTKKHIFQIHTSRMTLANDVTLDDLIM 360
           KVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKTKKHIFQIHTSRMTLANDVTLDDLIM
Sbjct: 301 KVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKTKKHIFQIHTSRMTLANDVTLDDLIM 360

Query: 361 AKDDFSGADIKAICTEAGLMALREHRMKATNEDFKKSIESVLYKKHEGIPEGLYL 415
           AKDDFSGADIKAICTEAGLMALREHRMKATNEDFKKSIESVLYKKHEGIPEGLYL
Sbjct: 361 AKDDFSGADIKAICTEAGLMALREHRMKATNEDFKKSIESVLYKKHEGIPEGLYL 415


>gi|24430151 proteasome 26S ATPase subunit 1 [Homo sapiens]
          Length = 440

 Score =  669 bits (1726), Expect = 0.0
 Identities = 346/412 (83%), Positives = 367/412 (89%), Gaps = 16/412 (3%)

Query: 18  TRVAEKEEKTKGQDVASKLPLVTLHTQCRLKLLKLERIKDYLLMVEEFIRNQEQIKLLEE 77
           TRV +K++KTKG D ASKLPLVT HTQCRLKLLKLERIKDYLLM EEFIRNQEQ+K LEE
Sbjct: 31  TRVGKKKKKTKGPDAASKLPLVTPHTQCRLKLLKLERIKDYLLMEEEFIRNQEQMKPLEE 90

Query: 78  KQEEGRSKVDDLRGTPMSVGNLEEIIDDNHAIVSTSVGSEHYDSIISFVEKDLLEPGCSI 137
           KQEE RSKVDDLRGTPMSVG LEEIIDDNHAIVSTSVGSEHY SI+SFV+KDLLEPGCS+
Sbjct: 91  KQEEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSV 150

Query: 138 LLRHKVHAVIGVLMDDTGPLVTMMKVEKAPQETYVNTGGLDNQIQEIKESMELPLPHPEY 197
           LL HKVHAVIGVLMDDT PLVT+MKVEKAPQETY + GGLDNQIQEIKES+ELPL HPEY
Sbjct: 151 LLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEY 210

Query: 198 YEEMGTKPPKGVILCGPPGT--------------ATFLRVVGSELIQKYLGDGPKLVRQV 243
           YEEMG KPPKGVIL GPPGT              ATFLRVVGSELIQKYLGDGPKLVR++
Sbjct: 211 YEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVREL 270

Query: 244 FQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGEREIQQTMLELELLNQLGGFDSREDVKVI 303
           F+VAEEHAPSI+F DEI+AIGTKRYDSNSGGEREIQ+TM  LELLNQL GFDSR DVKVI
Sbjct: 271 FRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTM--LELLNQLDGFDSRGDVKVI 328

Query: 304 MATKQVETLDPVLIRPGRIDKKIEFHLPDEKTKKHIFQIHTSRMTLANDVTLDDLIMAKD 363
           MAT ++ETLDP LIRPGRID+KIEF LPDEKTKK IFQIHTSRMTLA+DVTLDDLIMAKD
Sbjct: 329 MATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKD 388

Query: 364 DFSGADIKAICTEAGLMALREHRMKATNEDFKKSIESVLYKKHEGIPEGLYL 415
           D SGADIKAICTEAGLMALRE RMK TNEDFKKS E+VLYKK EG PEGLYL
Sbjct: 389 DLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYKKQEGTPEGLYL 440


>gi|89064750 PREDICTED: similar to proteasome 26S ATPase subunit 4
           [Homo sapiens]
          Length = 414

 Score =  317 bits (812), Expect = 1e-86
 Identities = 157/371 (42%), Positives = 253/371 (68%), Gaps = 18/371 (4%)

Query: 51  KLERIKDYLLMVEEFIRNQEQIKLLEEKQEEGRSKVDDLRGTPMSVGNLEEIIDDNHAIV 110
           KL++  ++L + EE+I++++  K L+++    + +V  ++  P+ +G   E +D N AIV
Sbjct: 42  KLQQELEFLEVQEEYIKDEQ--KNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIV 99

Query: 111 STSVGSEHYDSIISFVEKDLLEPGCSILLRHKVHAVIGVLMDDTGPLVTMMKVEKAPQET 170
            ++ GS +Y  I+S ++++LL+P  S+ L    +A++ VL  +    + M+  ++ P   
Sbjct: 100 GSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVM 159

Query: 171 YVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPG-------------- 216
           Y + GG+D Q QE++E++ELPL H E Y+++G  PP+GV++ GPPG              
Sbjct: 160 YADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHT 219

Query: 217 TATFLRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGER 276
           TA F+RVVGSE +QKYLG+GP++VR VF++A+E+AP+I+F DEI+AI TKR+D+ +G +R
Sbjct: 220 TAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADR 279

Query: 277 EIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKTK 336
           E+Q+ +LEL  LNQ+ GFD   +VKVIMAT + +TLDP L+RPGR+D+KIEF LPD + K
Sbjct: 280 EVQRILLEL--LNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQK 337

Query: 337 KHIFQIHTSRMTLANDVTLDDLIMAKDDFSGADIKAICTEAGLMALREHRMKATNEDFKK 396
           + IF   TS+M L+ +V L+D +   D  SGADI +IC E+G++A+RE+R     +DF+K
Sbjct: 338 RLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEK 397

Query: 397 SIESVLYKKHE 407
           + ++V+ K  +
Sbjct: 398 AYKTVIKKDEQ 408


>gi|5729991 proteasome 26S ATPase subunit 4 isoform 1 [Homo sapiens]
          Length = 418

 Score =  317 bits (812), Expect = 1e-86
 Identities = 157/371 (42%), Positives = 253/371 (68%), Gaps = 18/371 (4%)

Query: 51  KLERIKDYLLMVEEFIRNQEQIKLLEEKQEEGRSKVDDLRGTPMSVGNLEEIIDDNHAIV 110
           KL++  ++L + EE+I++++  K L+++    + +V  ++  P+ +G   E +D N AIV
Sbjct: 46  KLQQELEFLEVQEEYIKDEQ--KNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIV 103

Query: 111 STSVGSEHYDSIISFVEKDLLEPGCSILLRHKVHAVIGVLMDDTGPLVTMMKVEKAPQET 170
            ++ GS +Y  I+S ++++LL+P  S+ L    +A++ VL  +    + M+  ++ P   
Sbjct: 104 GSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVM 163

Query: 171 YVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPG-------------- 216
           Y + GG+D Q QE++E++ELPL H E Y+++G  PP+GV++ GPPG              
Sbjct: 164 YADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHT 223

Query: 217 TATFLRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGER 276
           TA F+RVVGSE +QKYLG+GP++VR VF++A+E+AP+I+F DEI+AI TKR+D+ +G +R
Sbjct: 224 TAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADR 283

Query: 277 EIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKTK 336
           E+Q+ +LEL  LNQ+ GFD   +VKVIMAT + +TLDP L+RPGR+D+KIEF LPD + K
Sbjct: 284 EVQRILLEL--LNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQK 341

Query: 337 KHIFQIHTSRMTLANDVTLDDLIMAKDDFSGADIKAICTEAGLMALREHRMKATNEDFKK 396
           + IF   TS+M L+ +V L+D +   D  SGADI +IC E+G++A+RE+R     +DF+K
Sbjct: 342 RLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEK 401

Query: 397 SIESVLYKKHE 407
           + ++V+ K  +
Sbjct: 402 AYKTVIKKDEQ 412


>gi|24430155 proteasome 26S ATPase subunit 4 isoform 2 [Homo
           sapiens]
          Length = 387

 Score =  309 bits (792), Expect = 3e-84
 Identities = 151/347 (43%), Positives = 235/347 (67%), Gaps = 16/347 (4%)

Query: 75  LEEKQEEGRSKVDDLRGTPMSVGNLEEIIDDNHAIVSTSVGSEHYDSIISFVEKDLLEPG 134
           LE+     + +V  ++  P+ +G   E +D N AIV ++ GS +Y  I+S ++++LL+P 
Sbjct: 37  LEDLYSRYKEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPN 96

Query: 135 CSILLRHKVHAVIGVLMDDTGPLVTMMKVEKAPQETYVNTGGLDNQIQEIKESMELPLPH 194
            S+ L    +A++ VL  +    + M+  ++ P   Y + GG+D Q QE++E++ELPL H
Sbjct: 97  ASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTH 156

Query: 195 PEYYEEMGTKPPKGVILCGPPG--------------TATFLRVVGSELIQKYLGDGPKLV 240
            E Y+++G  PP+GV++ GPPG              TA F+RVVGSE +QKYLG+GP++V
Sbjct: 157 FELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMV 216

Query: 241 RQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGEREIQQTMLELELLNQLGGFDSREDV 300
           R VF++A+E+AP+I+F DEI+AI TKR+D+ +G +RE+Q+ +LEL  LNQ+ GFD   +V
Sbjct: 217 RDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLEL--LNQMDGFDQNVNV 274

Query: 301 KVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKTKKHIFQIHTSRMTLANDVTLDDLIM 360
           KVIMAT + +TLDP L+RPGR+D+KIEF LPD + K+ IF   TS+M L+ +V L+D + 
Sbjct: 275 KVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVA 334

Query: 361 AKDDFSGADIKAICTEAGLMALREHRMKATNEDFKKSIESVLYKKHE 407
             D  SGADI +IC E+G++A+RE+R     +DF+K+ ++V+ K  +
Sbjct: 335 RPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQ 381


>gi|24497435 proteasome 26S ATPase subunit 5 [Homo sapiens]
          Length = 406

 Score =  281 bits (720), Expect = 6e-76
 Identities = 152/379 (40%), Positives = 230/379 (60%), Gaps = 20/379 (5%)

Query: 47  LKLLKLERIKDYLLMVEEFIRN----QEQIKLLEEKQEEGRSKVDDLRGTPMSVGNLEEI 102
           L+   L +I++  L+V +  +N    Q Q   L  K    R ++  L+     VG +   
Sbjct: 20  LRQYYLSKIEELQLIVNDKSQNLRRLQAQRNELNAKVRLLREELQLLQEQGSYVGEVVRA 79

Query: 103 IDDNHAIVSTSVGSEHYDSIISFVEKDLLEPGCSILLRHKVHAVIGVLMDDTGPLVTMMK 162
           +D    +V      +    +   ++ + + P C + LR+  + +  +L +   PLV++M 
Sbjct: 80  MDKKKVLVKVHPEGKFVVDVDKNIDINDVTPNCRVALRNDSYTLHKILPNKVDPLVSLMM 139

Query: 163 VEKAPQETYVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTA---- 218
           VEK P  TY   GGLD QI+EIKE +ELP+ HPE +E +G   PKGV+L GPPGT     
Sbjct: 140 VEKVPDSTYEMIGGLDKQIKEIKEVIELPVKHPELFEALGIAQPKGVLLYGPPGTGKTLL 199

Query: 219 ----------TFLRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRY 268
                     TF+RV GSEL+QK++G+G ++VR++F +A EHAPSI+F DEI++IG+ R 
Sbjct: 200 ARAVAHHTDCTFIRVSGSELVQKFIGEGARMVRELFVMAREHAPSIIFMDEIDSIGSSRL 259

Query: 269 DSNSGGEREIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEF 328
           +  SGG+ E+Q+TMLEL  LNQL GF++ +++KVIMAT +++ LD  L+RPGRID+KIEF
Sbjct: 260 EGGSGGDSEVQRTMLEL--LNQLDGFEATKNIKVIMATNRIDILDSALLRPGRIDRKIEF 317

Query: 329 HLPDEKTKKHIFQIHTSRMTLANDVTLDDLIMAKDDFSGADIKAICTEAGLMALREHRMK 388
             P+E+ +  I +IH+ +M L   + L  +       SGA++K +CTEAG+ ALRE R+ 
Sbjct: 318 PPPNEEARLDILKIHSRKMNLTRGINLRKIAELMPGASGAEVKGVCTEAGMYALRERRVH 377

Query: 389 ATNEDFKKSIESVLYKKHE 407
            T EDF+ ++  V+ K  E
Sbjct: 378 VTQEDFEMAVAKVMQKDSE 396


>gi|21361144 proteasome 26S ATPase subunit 3 [Homo sapiens]
          Length = 439

 Score =  280 bits (717), Expect = 1e-75
 Identities = 163/433 (37%), Positives = 249/433 (57%), Gaps = 43/433 (9%)

Query: 7   ELPAVAAQVAKTRVAEKEEKTKGQDVASKLPLVTLHTQCRLKLLKLERIKDYLLMVEEFI 66
           E P    +   T   E E+   G++V   L + T     R +LL  E IK   +M  E +
Sbjct: 8   ESPVTRQEKMATVWDEAEQDGIGEEV---LKMSTEEIIQRTRLLDSE-IK---IMKSEVL 60

Query: 67  RNQEQIKLLEEKQEEGRSKVDDLRGTPMSVGNLEEIIDDNH------------------- 107
           R   +++ +++K +E   K+   +  P  V N+ E++D +                    
Sbjct: 61  RVTHELQAMKDKIKENSEKIKVNKTLPYLVSNVIELLDVDPNDQEEDGANIDLDSQRKGK 120

Query: 108 -AIVSTSVGSEHYDSIISFVEKDLLEPGCSILLRHKVHAVIGVLMDDTGPLVTMMKVEKA 166
            A++ TS    ++  +I  V+ + L+PG  + +    + ++  L  +    V  M+V++ 
Sbjct: 121 CAVIKTSTRQTYFLPVIGLVDAEKLKPGDLVGVNKDSYLILETLPTEYDSRVKAMEVDER 180

Query: 167 PQETYVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGT--------- 217
           P E Y + GGLD QIQE+ E++ LP+ H E +E +G +PPKGV++ GPPGT         
Sbjct: 181 PTEQYSDIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMYGPPGTGKTLLARAC 240

Query: 218 -----ATFLRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNS 272
                ATFL++ G +L+Q ++GDG KLVR  F +A+E APSI+F DE++AIGTKR+DS  
Sbjct: 241 AAQTKATFLKLAGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFIDELDAIGTKRFDSEK 300

Query: 273 GGEREIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEFHLPD 332
            G+RE+Q+TMLEL  LNQL GF     VKVI AT +V+ LDP L+R GR+D+KIEF +P+
Sbjct: 301 AGDREVQRTMLEL--LNQLDGFQPNTQVKVIAATNRVDILDPALLRSGRLDRKIEFPMPN 358

Query: 333 EKTKKHIFQIHTSRMTLANDVTLDDLIMAKDDFSGADIKAICTEAGLMALREHRMKATNE 392
           E+ +  I QIH+ +M ++ DV  ++L    DDF+GA  KA+C EAG++ALR    + T+E
Sbjct: 359 EEARARIMQIHSRKMNVSPDVNYEELARCTDDFNGAQCKAVCVEAGMIALRRGATELTHE 418

Query: 393 DFKKSIESVLYKK 405
           D+ + I  V  KK
Sbjct: 419 DYMEGILEVQAKK 431


>gi|4506209 proteasome 26S ATPase subunit 2 [Homo sapiens]
          Length = 433

 Score =  252 bits (644), Expect = 4e-67
 Identities = 126/287 (43%), Positives = 192/287 (66%), Gaps = 21/287 (7%)

Query: 140 RHKVHAVIGVLMDDTGPLVTMMKVEKAPQETYVNTGGLDNQIQEIKESMELPLPHPEYYE 199
           ++++H  +   +D   P VTMM+VE+ P  TY + GG   QI++++E +E PL HPE + 
Sbjct: 146 KYQIHIPLPPKID---PTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFV 202

Query: 200 EMGTKPPKGVILCGPPGT--------------ATFLRVVGSELIQKYLGDGPKLVRQVFQ 245
            +G +PPKGV+L GPPGT              A F+RV+GSEL+QKY+G+G ++VR++F+
Sbjct: 203 NLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFE 262

Query: 246 VAEEHAPSIMFTDEIEAIGTKRYDSNSGGEREIQQTMLELELLNQLGGFDSREDVKVIMA 305
           +A      ++F DEI+AIG  R+D  +GG+ E+Q+TMLEL  +NQL GFD R ++KV+MA
Sbjct: 263 MARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLEL--INQLDGFDPRGNIKVLMA 320

Query: 306 TKQVETLDPVLIRPGRIDKKIEFHLPDEKTKKHIFQIHTSRMTLANDVTLDDLIMAKDDF 365
           T + +TLDP L+RPGR+D+KIEF LPD + + HIF+IH   M++  D+  + L     + 
Sbjct: 321 TNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNS 380

Query: 366 SGADIKAICTEAGLMALREHRMKATNEDFKKSIESVL--YKKHEGIP 410
           +GA+I+++CTEAG+ A+R  R  AT +DF +++  V+  Y K    P
Sbjct: 381 TGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYAKFSATP 427


>gi|195539395 proteasome 26S ATPase subunit 6 [Homo sapiens]
          Length = 403

 Score =  241 bits (616), Expect = 7e-64
 Identities = 126/351 (35%), Positives = 202/351 (57%), Gaps = 16/351 (4%)

Query: 69  QEQIKLLEEKQEEGRSKVDDLRGTPMSVGNLEEIIDDNHAIVSTSVGSEHYDSIISFVEK 128
           +EQ+K L ++ E+  + +  L+     VG + + + +   IV  + G  +       ++K
Sbjct: 44  REQLKELTKQYEKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDK 103

Query: 129 DLLEPGCSILLRHKVHAVIGVLMDDTGPLVTMMKVEKAPQETYVNTGGLDNQIQEIKESM 188
             L+PG  + L      ++  L  +  PLV  M  E     +Y   GGL  QI+E++E +
Sbjct: 104 SKLKPGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVI 163

Query: 189 ELPLPHPEYYEEMGTKPPKGVILCGPPGTA--------------TFLRVVGSELIQKYLG 234
           ELPL +PE ++ +G  PPKG +L GPPGT                FL+VV S ++ KY+G
Sbjct: 164 ELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIG 223

Query: 235 DGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGEREIQQTMLELELLNQLGGF 294
           +  +L+R++F  A +H P I+F DEI+AIG +R+   +  +REIQ+T++EL  LNQ+ GF
Sbjct: 224 ESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMEL--LNQMDGF 281

Query: 295 DSREDVKVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKTKKHIFQIHTSRMTLANDVT 354
           D+   VK+IMAT + +TLDP L+RPGR+D+KI   LP+E+ +  I +IH   +T   ++ 
Sbjct: 282 DTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHGEID 341

Query: 355 LDDLIMAKDDFSGADIKAICTEAGLMALREHRMKATNEDFKKSIESVLYKK 405
            + ++   D F+GAD++ +CTEAG+ A+R        EDF K++  V   K
Sbjct: 342 YEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAVRKVADSK 392


>gi|157671927 spermatogenesis associated 5 [Homo sapiens]
          Length = 893

 Score =  168 bits (426), Expect = 7e-42
 Identities = 98/277 (35%), Positives = 154/277 (55%), Gaps = 19/277 (6%)

Query: 151 MDDTGPLVTMMKVEKAPQETYVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVI 210
           M+D  P          P  ++ + GGL++   ++++++E PL HPE +  MG +PPKGV+
Sbjct: 606 MNDIRPSAMREIAIDVPNVSWSDIGGLESIKLKLEQAVEWPLKHPESFIRMGIQPPKGVL 665

Query: 211 LCGPPGTA--------------TFLRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMF 256
           L GPPG +               FL + G EL+ KY+G+  + VR+ F+ A   APSI+F
Sbjct: 666 LYGPPGCSKTMIAKALANESGLNFLAIKGPELMNKYVGESERAVRETFRKARAVAPSIIF 725

Query: 257 TDEIEAIGTKRYDSNSGGEREIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVL 316
            DE++A+  +R  S   G   +   +L  +LL ++ G +  +DV ++ AT + + +D  L
Sbjct: 726 FDELDALAVERGSSLGAGN--VADRVLA-QLLTEMDGIEQLKDVTILAATNRPDRIDKAL 782

Query: 317 IRPGRIDKKIEFHLPDEKTKKHIFQIHTSRMTLANDVTLDDLIMAKDDFSGADIKAICTE 376
           +RPGRID+ I   LPD  T++ IF++    M ++N+V LD+LI+  D +SGA+I A+C E
Sbjct: 783 MRPGRIDRIIYVPLPDAATRREIFKLQFHSMPVSNEVDLDELILQTDAYSGAEIVAVCRE 842

Query: 377 AGLMALREHRMKATNEDFKKSIESVLYKKHEGIPEGL 413
           A L+AL E      N   K+     L      IPE L
Sbjct: 843 AALLALEEDIQ--ANLIMKRHFTQALSTVTPRIPESL 877



 Score =  132 bits (333), Expect = 4e-31
 Identities = 84/237 (35%), Positives = 127/237 (53%), Gaps = 17/237 (7%)

Query: 170 TYVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGT------------ 217
           TY   GGL +Q++ I+E +ELPL  PE ++  G   P+GV+L GPPGT            
Sbjct: 351 TYDMIGGLSSQLKAIREIIELPLKQPELFKSYGIPAPRGVLLYGPPGTGKTMIARAVANE 410

Query: 218 -ATFLRVV-GSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGE 275
              ++ V+ G E+I K+ G+    +RQ+F  A    PSI+F DE++A+  KR  + +  E
Sbjct: 411 VGAYVSVINGPEIISKFYGETEAKLRQIFAEATLRHPSIIFIDELDALCPKREGAQNEVE 470

Query: 276 REIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKT 335
           + +  ++  L L++ +G   S   V V+ AT +   LD  L RPGR DK+IE  +P+ + 
Sbjct: 471 KRVVASL--LTLMDGIGSEVSEGQVLVLGATNRPHALDAALRRPGRFDKEIEIGVPNAQD 528

Query: 336 KKHIFQIHTSRMT-LANDVTLDDLIMAKDDFSGADIKAICTEAGLMALREHRMKATN 391
           +  I Q    R+  L  +  L  L  +   + GAD+K +C EAGL ALR    K  N
Sbjct: 529 RLDILQKLLRRVPHLLTEAELLQLANSAHGYVGADLKVLCNEAGLCALRRILKKQPN 585


>gi|6005942 valosin-containing protein [Homo sapiens]
          Length = 806

 Score =  156 bits (395), Expect = 3e-38
 Identities = 85/228 (37%), Positives = 130/228 (57%), Gaps = 19/228 (8%)

Query: 171 YVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGT------------- 217
           Y + GG   Q+ +IKE +ELPL HP  ++ +G KPP+G++L GPPGT             
Sbjct: 203 YDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRGILLYGPPGTGKTLIARAVANET 262

Query: 218 -ATFLRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGER 276
            A F  + G E++ K  G+    +R+ F+ AE++AP+I+F DE++AI  KR  ++   ER
Sbjct: 263 GAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAIIFIDELDAIAPKREKTHGEVER 322

Query: 277 EIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKTK 336
            I   +L L     + G   R  V V+ AT +  ++DP L R GR D++++  +PD   +
Sbjct: 323 RIVSQLLTL-----MDGLKQRAHVIVMAATNRPNSIDPALRRFGRFDREVDIGIPDATGR 377

Query: 337 KHIFQIHTSRMTLANDVTLDDLIMAKDDFSGADIKAICTEAGLMALRE 384
             I QIHT  M LA+DV L+ +        GAD+ A+C+EA L A+R+
Sbjct: 378 LEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAALQAIRK 425



 Score =  147 bits (371), Expect = 2e-35
 Identities = 90/314 (28%), Positives = 164/314 (52%), Gaps = 34/314 (10%)

Query: 98  NLEEIIDDNHAIVSTSVGSEHYDSIISFVEK--DLLEPGCSILLRHKVHAVIGVLMDD-- 153
           +LE++ ++ H  V   + +   ++ +  + K  DL++     +    +++ + V MDD  
Sbjct: 395 DLEQVANETHGHVGADLAALCSEAALQAIRKKMDLIDLEDETIDAEVMNS-LAVTMDDFR 453

Query: 154 -----TGPLVTMMKVEKAPQETYVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKG 208
                + P      V + PQ T+ + GGL++  +E++E ++ P+ HP+ + + G  P KG
Sbjct: 454 WALSQSNPSALRETVVEVPQVTWEDIGGLEDVKRELQELVQYPVEHPDKFLKFGMTPSKG 513

Query: 209 VILCGPPGT--------------ATFLRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSI 254
           V+  GPPG               A F+ + G EL+  + G+    VR++F  A + AP +
Sbjct: 514 VLFYGPPGCGKTLLAKAIANECQANFISIKGPELLTMWFGESEANVREIFDKARQAAPCV 573

Query: 255 MFTDEIEAIGTKRY----DSNSGGEREIQQTMLELELLNQLGGFDSREDVKVIMATKQVE 310
           +F DE+++I   R     D     +R I Q + E++      G  ++++V +I AT + +
Sbjct: 574 LFFDELDSIAKARGGNIGDGGGAADRVINQILTEMD------GMSTKKNVFIIGATNRPD 627

Query: 311 TLDPVLIRPGRIDKKIEFHLPDEKTKKHIFQIHTSRMTLANDVTLDDLIMAKDDFSGADI 370
            +DP ++RPGR+D+ I   LPDEK++  I + +  +  +A DV L+ L    + FSGAD+
Sbjct: 628 IIDPAILRPGRLDQLIYIPLPDEKSRVAILKANLRKSPVAKDVDLEFLAKMTNGFSGADL 687

Query: 371 KAICTEAGLMALRE 384
             IC  A  +A+RE
Sbjct: 688 TEICQRACKLAIRE 701


>gi|5802970 AFG3 ATPase family gene 3-like 2 [Homo sapiens]
          Length = 797

 Score =  151 bits (381), Expect = 1e-36
 Identities = 88/250 (35%), Positives = 137/250 (54%), Gaps = 21/250 (8%)

Query: 171 YVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTAT----------- 219
           + +  G +    EI E +   L +P+ Y+++G K PKG IL GPPGT             
Sbjct: 307 FKDVAGCEEAKLEIMEFVNF-LKNPKQYQDLGAKIPKGAILTGPPGTGKTLLAKATAGEA 365

Query: 220 ---FLRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGER 276
              F+ V GSE ++ ++G GP  VR +F +A ++AP I+F DEI+A+G KR   N GG+ 
Sbjct: 366 NVPFITVSGSEFLEMFVGVGPARVRDLFALARKNAPCILFIDEIDAVGRKRGRGNFGGQS 425

Query: 277 EIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKTK 336
           E + T+   +LL ++ GF++  +V ++  T + + LDP L+RPGR D++I    PD K +
Sbjct: 426 EQENTL--NQLLVEMDGFNTTTNVVILAGTNRPDILDPALLRPGRFDRQIFIGPPDIKGR 483

Query: 337 KHIFQIHTSRM----TLANDVTLDDLIMAKDDFSGADIKAICTEAGLMALREHRMKATNE 392
             IF++H   +    TL  D     L      FSGAD+  +C EA L+A R        +
Sbjct: 484 ASIFKVHLRPLKLDSTLEKDKLARKLASLTPGFSGADVANVCNEAALIAARHLSDSINQK 543

Query: 393 DFKKSIESVL 402
            F+++IE V+
Sbjct: 544 HFEQAIERVI 553


>gi|153792536 ATPase family, AAA domain containing 2B [Homo sapiens]
          Length = 1458

 Score =  145 bits (366), Expect = 7e-35
 Identities = 92/287 (32%), Positives = 151/287 (52%), Gaps = 35/287 (12%)

Query: 138 LLRHKVHAVIGVLMDDTGPLVTMMKVEKAPQETYVNTGGLDNQIQEIKESMELPLPHPEY 197
           +LR +V   +G  + D  P    M ++K+ +  + + GGL + I  +KE +  PL +PE 
Sbjct: 374 ILRERVK--VGASLADVDP----MNIDKSVR--FDSIGGLSHHIHALKEMVVFPLLYPEI 425

Query: 198 YEEMGTKPPKGVILCGPPGTA-------------------TFLRVVGSELIQKYLGDGPK 238
           +E+   +PP+G +  GPPGT                     F    G++ + K++G+  +
Sbjct: 426 FEKFKIQPPRGCLFYGPPGTGKTLVARALANECSQGDKKVAFFMRKGADCLSKWVGESER 485

Query: 239 LVRQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGEREIQQTMLELELLNQLGGFDSRE 298
            +R +F  A    PSI+F DEI+ +   R          I  T+L L     + G D+R 
Sbjct: 486 QLRLLFDQAYLMRPSIIFFDEIDGLAPVRSSRQDQIHSSIVSTLLAL-----MDGLDNRG 540

Query: 299 DVKVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKTKKHIFQIHTSRMT-LANDVTLDD 357
           ++ VI AT +++++DP L RPGR D++  F+LPD+K +KHI QIHT       +D  L +
Sbjct: 541 EIVVIGATNRLDSIDPALRRPGRFDREFLFNLPDQKARKHILQIHTRDWNPKLSDAFLGE 600

Query: 358 LIMAKDDFSGADIKAICTEAGLMALREH--RMKATNEDFKKSIESVL 402
           L      + GADIKA+CTEA L+ALR    ++ A++   +  + S++
Sbjct: 601 LAEKCVGYCGADIKALCTEAALIALRRRYPQIYASSHKLQLDVSSIV 647


>gi|229577436 spermatogenesis associated 5-like 1 [Homo sapiens]
          Length = 753

 Score =  144 bits (362), Expect = 2e-34
 Identities = 92/263 (34%), Positives = 144/263 (54%), Gaps = 39/263 (14%)

Query: 175 GGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTA--------------TF 220
           GGL++   ++K+S+E PL  P  +  MG   PKGV+L GPPG A              +F
Sbjct: 467 GGLEDVKLKLKQSIEWPLKFPWEFVRMGLTQPKGVLLYGPPGCAKTTLVRALATSCHCSF 526

Query: 221 LRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGEREIQQ 280
           + V G++L   ++GD  K++ Q+F+ A    P+I+F DEI++I   R  S +G +  +Q+
Sbjct: 527 VSVSGADLFSPFVGDSEKVLSQIFRQARASTPAILFLDEIDSILGARSASKTGCD--VQE 584

Query: 281 TMLELELLNQLGGFDSR-------------------EDVKVIMATKQVETLDPVLIRPGR 321
            +L + LLN+L G   +                     V +I AT + + LD  L+RPGR
Sbjct: 585 RVLSV-LLNELDGVGLKTIERRGSKSSQQEFQEVFNRSVMIIAATNRPDVLDTALLRPGR 643

Query: 322 IDKKIEFHLPDEKTKKHIFQIHTSRMTLANDVTLDDLIMAKDDFSGADIKAICTEAGLMA 381
           +DK I    PD K +  I ++ T  M +  DV+L++L      FSGAD++ +CTEA L+A
Sbjct: 644 LDKIIYIPPPDHKGRLSILKVCTKTMPIGPDVSLENLAAETCFFSGADLRNLCTEAALLA 703

Query: 382 LREHRMKAT---NEDFKKSIESV 401
           L+E+ + AT    E F KS+++V
Sbjct: 704 LQENGLDATTVKQEHFLKSLKTV 726



 Score =  112 bits (281), Expect = 5e-25
 Identities = 77/235 (32%), Positives = 119/235 (50%), Gaps = 24/235 (10%)

Query: 165 KAPQETYVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTA------ 218
           +A  +  V  GGL      ++E + LPL +P     +G   P+GV+L GPPG        
Sbjct: 193 EAQPQPEVPLGGLSEAADSLRELLRLPLRYPRALTALGLAVPRGVLLAGPPGVGKTQLVR 252

Query: 219 TFLRVVGSELIQKYL--------GDGPKLVRQVFQVAEEHA---PSIMFTDEIEAIGTKR 267
              R  G+EL+            G+  + VR+VFQ A E A   PS++F DE++A+  +R
Sbjct: 253 AVAREAGAELLAVSAPALQGSRPGETEENVRRVFQRARELASRGPSLLFLDEMDALCPQR 312

Query: 268 YDSNSGGEREIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIE 327
                 G R  +  ++  ++L  L G     +V V+ AT + + LDP L RPGR D+++ 
Sbjct: 313 ------GSRAPESRVVA-QVLTLLDGASGDREVVVVGATNRPDALDPALRRPGRFDREVV 365

Query: 328 FHLPDEKTKKHIFQIHTSRMTLANDVTLDDLIMAKDDFSGADIKAICTEAGLMAL 382
              P  K +K I Q+ TS+M +++ V L  L      + GAD+ A+C EA + AL
Sbjct: 366 IGTPTLKQRKEILQVITSKMPISSHVDLGLLAEMTVGYVGADLTALCREAAMHAL 420


>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
          Length = 1390

 Score =  138 bits (347), Expect = 1e-32
 Identities = 89/283 (31%), Positives = 140/283 (49%), Gaps = 33/283 (11%)

Query: 141 HKVHAVIGVLMDDTGPLVTMMKVEKAPQETYVNTGGLDNQIQEIKESMELPLPHPEYYEE 200
           +K    IG  + D  P+     V       + + GGL N I  +KE +  PL +PE +E+
Sbjct: 401 YKDRMKIGASLADVDPMQLDSSVR------FDSVGGLSNHIAALKEMVVFPLLYPEVFEK 454

Query: 201 MGTKPPKGVILCGPPGTA-------------------TFLRVVGSELIQKYLGDGPKLVR 241
              +PP+G +  GPPGT                     F    G++ + K++G+  + +R
Sbjct: 455 FKIQPPRGCLFYGPPGTGKTLVARALANECSQGDKRVAFFMRKGADCLSKWVGESERQLR 514

Query: 242 QVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGEREIQQTMLELELLNQLGGFDSREDVK 301
            +F  A +  PSI+F DEI+ +   R          I  T+L L     + G DSR ++ 
Sbjct: 515 LLFDQAYQMRPSIIFFDEIDGLAPVRSSRQDQIHSSIVSTLLAL-----MDGLDSRGEIV 569

Query: 302 VIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKTKKHIFQIHTSRMT-LANDVTLDDLIM 360
           VI AT +++++DP L RPGR D++  F LPD++ +K I +IHT        D  L++L  
Sbjct: 570 VIGATNRLDSIDPALRRPGRFDREFLFSLPDKEARKEILKIHTRDWNPKPLDTFLEELAE 629

Query: 361 AKDDFSGADIKAICTEAGLMALREH--RMKATNEDFKKSIESV 401
               + GADIK+IC EA L ALR    ++  T+E  +  + S+
Sbjct: 630 NCVGYCGADIKSICAEAALCALRRRYPQIYTTSEKLQLDLSSI 672


>gi|4505725 peroxin1 [Homo sapiens]
          Length = 1283

 Score =  131 bits (330), Expect = 1e-30
 Identities = 80/243 (32%), Positives = 127/243 (52%), Gaps = 21/243 (8%)

Query: 175  GGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTA--------------TF 220
            GGL    Q + ++++LP  +PE +  +  +   G++L GPPGT                F
Sbjct: 843  GGLHEVRQILMDTIQLPAKYPELFANLPIRQRTGILLYGPPGTGKTLLAGVIARESRMNF 902

Query: 221  LRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSG-GEREIQ 279
            + V G EL+ KY+G   + VR +F  A+   P I+F DE E+I  +R   N+G  +R + 
Sbjct: 903  ISVKGPELLSKYIGASEQAVRDIFIRAQAAKPCILFFDEFESIAPRRGHDNTGVTDRVVN 962

Query: 280  QTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKTKKHI 339
            Q      LL QL G +  + V V+ AT + + +DP L+RPGR+DK +    PD+ ++  I
Sbjct: 963  Q------LLTQLDGVEGLQGVYVLAATSRPDLIDPALLRPGRLDKCVYCPPPDQVSRLEI 1016

Query: 340  FQIHTSRMTLANDVTLDDLIMAKDDFSGADIKAICTEAGLMALREHRMKATNEDFKKSIE 399
              + +  + LA+DV L  +    D F+GAD+KA+   A L AL    + +  +D   S +
Sbjct: 1017 LNVLSDSLPLADDVDLQHVASVTDSFTGADLKALLYNAQLEALHGMLLSSGLQDGSSSSD 1076

Query: 400  SVL 402
            S L
Sbjct: 1077 SDL 1079


>gi|45643125 nuclear VCP-like isoform 2 [Homo sapiens]
          Length = 750

 Score =  129 bits (324), Expect = 5e-30
 Identities = 77/247 (31%), Positives = 133/247 (53%), Gaps = 26/247 (10%)

Query: 167 PQETYVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTA-------- 218
           P  T+ + G L++  +E+  ++  P+ +P+ ++ +G   P GV+L GPPG          
Sbjct: 470 PNVTWADIGALEDIREELTMAILAPVRNPDQFKALGLVTPAGVLLAGPPGCGKTLLAKAV 529

Query: 219 ------TFLRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNS 272
                  F+ V G EL+  Y+G+  + VRQVFQ A+  AP ++F DE++A+  +R D  +
Sbjct: 530 ANESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDALCPRRSDRET 589

Query: 273 GGEREIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEFHLPD 332
           G    +       +LL ++ G ++R+ V ++ AT + + +DP ++RPGR+DK +   LP 
Sbjct: 590 GASVRVVN-----QLLTEMDGLEARQQVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPP 644

Query: 333 EKTKKHIFQIHTSRMT---LANDVTLDDLI--MAKDDFSGADIKAICTEAGLMALREH-- 385
              +  I +  T   T   L  DV L+ +   +  D ++GAD+ A+  EA + ALR+   
Sbjct: 645 PADRLAILKTITKNGTKPPLDADVNLEAIAGDLRCDCYTGADLSALVREASICALRQEMA 704

Query: 386 RMKATNE 392
           R K+ NE
Sbjct: 705 RQKSGNE 711



 Score =  117 bits (294), Expect = 1e-26
 Identities = 75/239 (31%), Positives = 120/239 (50%), Gaps = 17/239 (7%)

Query: 171 YVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTAT----------- 219
           + + GG D  ++E+ + M + + HPE Y  +G  PP+GV+L GPPG              
Sbjct: 158 FEDVGGNDMTLKEVCK-MLIHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHAIAGEL 216

Query: 220 ---FLRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGER 276
               L+V   E++    G+  + +R++F+ A  +AP I+F DEI+AI  KR  ++   ER
Sbjct: 217 DLPILKVAAPEIVSGVSGESEQKLRELFEQAVSNAPCIIFIDEIDAITPKREVASKDMER 276

Query: 277 EIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKTK 336
            I   +L    ++ L    +   V VI AT + ++LDP L R GR D++I   +PDE ++
Sbjct: 277 RIVAQLLTC--MDDLNNVAATARVLVIGATNRPDSLDPALRRAGRFDREICLGIPDEASR 334

Query: 337 KHIFQIHTSRMTLANDVTLDDLIMAKDDFSGADIKAICTEAGLMALREHRMKATNEDFK 395
           + I Q    ++ L        L      F GAD+ A+C EA + A+    MK   +  K
Sbjct: 335 ERILQTLCRKLRLPQAFDFCHLAHLTPGFVGADLMALCREAAMCAVNRVLMKLQEQQKK 393


>gi|45643123 nuclear VCP-like isoform 1 [Homo sapiens]
          Length = 856

 Score =  129 bits (324), Expect = 5e-30
 Identities = 77/247 (31%), Positives = 133/247 (53%), Gaps = 26/247 (10%)

Query: 167 PQETYVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTA-------- 218
           P  T+ + G L++  +E+  ++  P+ +P+ ++ +G   P GV+L GPPG          
Sbjct: 576 PNVTWADIGALEDIREELTMAILAPVRNPDQFKALGLVTPAGVLLAGPPGCGKTLLAKAV 635

Query: 219 ------TFLRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNS 272
                  F+ V G EL+  Y+G+  + VRQVFQ A+  AP ++F DE++A+  +R D  +
Sbjct: 636 ANESGLNFISVKGPELLNMYVGESERAVRQVFQRAKNSAPCVIFFDEVDALCPRRSDRET 695

Query: 273 GGEREIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEFHLPD 332
           G    +       +LL ++ G ++R+ V ++ AT + + +DP ++RPGR+DK +   LP 
Sbjct: 696 GASVRVVN-----QLLTEMDGLEARQQVFIMAATNRPDIIDPAILRPGRLDKTLFVGLPP 750

Query: 333 EKTKKHIFQIHTSRMT---LANDVTLDDLI--MAKDDFSGADIKAICTEAGLMALREH-- 385
              +  I +  T   T   L  DV L+ +   +  D ++GAD+ A+  EA + ALR+   
Sbjct: 751 PADRLAILKTITKNGTKPPLDADVNLEAIAGDLRCDCYTGADLSALVREASICALRQEMA 810

Query: 386 RMKATNE 392
           R K+ NE
Sbjct: 811 RQKSGNE 817



 Score =  117 bits (294), Expect = 1e-26
 Identities = 75/239 (31%), Positives = 120/239 (50%), Gaps = 17/239 (7%)

Query: 171 YVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTAT----------- 219
           + + GG D  ++E+ + M + + HPE Y  +G  PP+GV+L GPPG              
Sbjct: 264 FEDVGGNDMTLKEVCK-MLIHMRHPEVYHHLGVVPPRGVLLHGPPGCGKTLLAHAIAGEL 322

Query: 220 ---FLRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGER 276
               L+V   E++    G+  + +R++F+ A  +AP I+F DEI+AI  KR  ++   ER
Sbjct: 323 DLPILKVAAPEIVSGVSGESEQKLRELFEQAVSNAPCIIFIDEIDAITPKREVASKDMER 382

Query: 277 EIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKTK 336
            I   +L    ++ L    +   V VI AT + ++LDP L R GR D++I   +PDE ++
Sbjct: 383 RIVAQLLTC--MDDLNNVAATARVLVIGATNRPDSLDPALRRAGRFDREICLGIPDEASR 440

Query: 337 KHIFQIHTSRMTLANDVTLDDLIMAKDDFSGADIKAICTEAGLMALREHRMKATNEDFK 395
           + I Q    ++ L        L      F GAD+ A+C EA + A+    MK   +  K
Sbjct: 441 ERILQTLCRKLRLPQAFDFCHLAHLTPGFVGADLMALCREAAMCAVNRVLMKLQEQQKK 499


>gi|4507173 spastic paraplegia 7 isoform 1 [Homo sapiens]
          Length = 795

 Score =  125 bits (313), Expect = 9e-29
 Identities = 79/249 (31%), Positives = 127/249 (51%), Gaps = 18/249 (7%)

Query: 170 TYVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTAT---------- 219
           ++ +  G+     E++E ++  L  PE + ++G K PKG +L GPPG             
Sbjct: 307 SFKDVAGMHEAKLEVREFVDY-LKSPERFLQLGAKVPKGALLLGPPGCGKTLLAKAVATE 365

Query: 220 ----FLRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGE 275
               FL + G E ++   G G   VR +F+ A   AP I++ DEI+A+G KR  + SG  
Sbjct: 366 AQVPFLAMAGPEFVEVIGGLGAARVRSLFKEARARAPCIVYIDEIDAVGKKRSTTMSGFS 425

Query: 276 REIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKT 335
              ++  L  +LL ++ G  + + V V+ +T + + LD  L+RPGR+D+ +   LP  + 
Sbjct: 426 NTEEEQTLN-QLLVEMDGMGTTDHVIVLASTNRADILDGALMRPGRLDRHVFIDLPTLQE 484

Query: 336 KKHIFQIHTSRMTLANDVTLDDLIMAK--DDFSGADIKAICTEAGLMALREHRMKATNED 393
           ++ IF+ H   + L    T     +A+    FSGADI  IC EA L A RE        +
Sbjct: 485 RREIFEQHLKSLKLTQSSTFYSQRLAELTPGFSGADIANICNEAALHAAREGHTSVHTLN 544

Query: 394 FKKSIESVL 402
           F+ ++E VL
Sbjct: 545 FEYAVERVL 553


>gi|194018488 peroxisomal biogenesis factor 6 [Homo sapiens]
          Length = 980

 Score =  114 bits (286), Expect = 1e-25
 Identities = 80/238 (33%), Positives = 124/238 (52%), Gaps = 27/238 (11%)

Query: 165 KAPQETYVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTA------ 218
           K P  ++ + GGL    +EI E+++LPL HPE    +G +   G++L GPPGT       
Sbjct: 698 KIPSVSWHDVGGLQEVKKEILETIQLPLEHPELLS-LGLRR-SGLLLHGPPGTGKTLLAK 755

Query: 219 --------TFLRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRYDS 270
                   TFL V G ELI  Y+G   + VR+VF  A   AP I+F DE++++   R  S
Sbjct: 756 AVATECSLTFLSVKGPELINMYVGQSEENVREVFARARAAAPCIIFFDELDSLAPSRGRS 815

Query: 271 NSGG---EREIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIE 327
              G   +R + Q      LL +L G  S +DV VI AT + + LDP L+RPGR DK + 
Sbjct: 816 GDSGGVMDRVVSQ------LLAELDGLHSTQDVFVIGATNRPDLLDPALLRPGRFDKLVF 869

Query: 328 FHLPDEKTKK-HIFQIHTSRMTLANDVTLDDLI-MAKDDFSGADIKAICTEAGLMALR 383
               +++  +  +    T +  L   V+L +++       +GAD+ ++C++A   AL+
Sbjct: 870 VGANEDRASQLRVLSAITRKFKLEPSVSLVNVLDCCPPQLTGADLYSLCSDAMTAALK 927


>gi|21327685 YME1-like 1 isoform 1 [Homo sapiens]
          Length = 773

 Score =  113 bits (283), Expect = 3e-25
 Identities = 73/247 (29%), Positives = 129/247 (52%), Gaps = 19/247 (7%)

Query: 170 TYVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTAT---------- 219
           T+ +  G++   QE++E +E  L +P+ +  +G K PKG++L GPPGT            
Sbjct: 337 TFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGE 395

Query: 220 ----FLRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGE 275
               F    GSE  + ++G G   +R +F+ A+ +AP ++F DE++++G KR +S     
Sbjct: 396 ADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPM--H 453

Query: 276 REIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKT 335
              +QT+ +L  L ++ GF   E V +I AT   E LD  LIRPGR D ++    PD K 
Sbjct: 454 PYSRQTINQL--LAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKG 511

Query: 336 KKHIFQIHTSRMTLANDVTLDDLIMAKDDFSGADIKAICTEAGLMALREHRMKATNEDFK 395
           +  I + + +++     V  + +      FSGA+++ +  +A L A  + +   T ++ +
Sbjct: 512 RTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKELE 571

Query: 396 KSIESVL 402
            S + +L
Sbjct: 572 FSKDKIL 578


>gi|7657689 YME1-like 1 isoform 3 [Homo sapiens]
          Length = 716

 Score =  113 bits (283), Expect = 3e-25
 Identities = 73/247 (29%), Positives = 129/247 (52%), Gaps = 19/247 (7%)

Query: 170 TYVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTAT---------- 219
           T+ +  G++   QE++E +E  L +P+ +  +G K PKG++L GPPGT            
Sbjct: 280 TFEHVKGVEEAKQELQEVVEF-LKNPQKFTILGGKLPKGILLVGPPGTGKTLLARAVAGE 338

Query: 220 ----FLRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGE 275
               F    GSE  + ++G G   +R +F+ A+ +AP ++F DE++++G KR +S     
Sbjct: 339 ADVPFYYASGSEFDEMFVGVGASRIRNLFREAKANAPCVIFIDELDSVGGKRIESPM--H 396

Query: 276 REIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKT 335
              +QT+ +L  L ++ GF   E V +I AT   E LD  LIRPGR D ++    PD K 
Sbjct: 397 PYSRQTINQL--LAEMDGFKPNEGVIIIGATNFPEALDNALIRPGRFDMQVTVPRPDVKG 454

Query: 336 KKHIFQIHTSRMTLANDVTLDDLIMAKDDFSGADIKAICTEAGLMALREHRMKATNEDFK 395
           +  I + + +++     V  + +      FSGA+++ +  +A L A  + +   T ++ +
Sbjct: 455 RTEILKWYLNKIKFDQSVDPEIIARGTVGFSGAELENLVNQAALKAAVDGKEMVTMKELE 514

Query: 396 KSIESVL 402
            S + +L
Sbjct: 515 FSKDKIL 521


>gi|113426932 PREDICTED: similar to N-ethylmaleimide-sensitive
           factor [Homo sapiens]
          Length = 563

 Score =  112 bits (280), Expect = 6e-25
 Identities = 76/244 (31%), Positives = 125/244 (51%), Gaps = 31/244 (12%)

Query: 175 GGLDNQIQEI-KESMELPLPHPEYYEEMGTKPPKGVILCGPPGTATFLR----------- 222
           GGLD +  +I + +    +  PE  E+MG K  KG++L GPPG    L            
Sbjct: 294 GGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAR 353

Query: 223 ----VVGSELIQKYLGDGPKLVRQVFQVAEEHAPS--------IMFTDEIEAIGTKRYDS 270
               V G E++ KY+G+    +R++F  AEE            I+  DEI+AI  +R   
Sbjct: 354 EPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQR--G 411

Query: 271 NSGGEREIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEFHL 330
           +  G   +  T++  +LL+++ G +   ++ VI  T + + +D  L+RPGR++ K+E  L
Sbjct: 412 SMAGSTGVHDTVVN-QLLSKIDGMEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGL 470

Query: 331 PDEKTKKHIFQIHTSRM----TLANDVTLDDLIMAKDDFSGADIKAICTEAGLMALREHR 386
           PDEK +  I  IHT+RM     L+ DV + +L +   +FSGA+++ +   A   A+  H 
Sbjct: 471 PDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHI 530

Query: 387 MKAT 390
             +T
Sbjct: 531 KAST 534


>gi|5901990 katanin p60 subunit A 1 [Homo sapiens]
          Length = 491

 Score =  112 bits (280), Expect = 6e-25
 Identities = 82/256 (32%), Positives = 130/256 (50%), Gaps = 45/256 (17%)

Query: 184 IKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTA--------------TFLRVVGSELI 229
           +KE++ LP+  PE+++ +  +P KGV++ GPPGT               TF  V  S L 
Sbjct: 221 LKEAVVLPMWMPEFFKGI-RRPWKGVLMVGPPGTGKTLLAKAVATECKTTFFNVSSSTLT 279

Query: 230 QKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGEREIQQTMLELELLN 289
            KY G+  KLVR +F++A  ++P+ +F DEI++I ++R  S    E       ++ ELL 
Sbjct: 280 SKYRGESEKLVRLLFEMARFYSPATIFIDEIDSICSRRGTS----EEHEASRRVKAELLV 335

Query: 290 QL---GGFDSRED----VKVIMATKQVETLDPVLIRPGRIDKKIEFHLPDEKTKKHIFQI 342
           Q+   GG    +D    V V+ AT     +D  L R  R++K+I   LP  K ++ + +I
Sbjct: 336 QMDGVGGTSENDDPSKMVMVLAATNFPWDIDEALRR--RLEKRIYIPLPSAKGREELLRI 393

Query: 343 HTSRMTLANDVTLDDLIMAKDDFSGADIKAICTEAGLMALR-----------------EH 385
               + LA+DV L  +    + +SGADI  +C +A LMA+R                 E 
Sbjct: 394 SLRELELADDVDLASIAENMEGYSGADITNVCRDASLMAMRRRIEGLTPEEIRNLSKEEM 453

Query: 386 RMKATNEDFKKSIESV 401
            M  T EDF+ +++ V
Sbjct: 454 HMPTTMEDFEMALKKV 469


>gi|156564401 vesicle-fusing ATPase [Homo sapiens]
          Length = 744

 Score =  112 bits (279), Expect = 8e-25
 Identities = 76/244 (31%), Positives = 125/244 (51%), Gaps = 31/244 (12%)

Query: 175 GGLDNQIQEI-KESMELPLPHPEYYEEMGTKPPKGVILCGPPGTATFLR----------- 222
           GGLD +  +I + +    +  PE  E+MG K  KG++L GPPG    L            
Sbjct: 221 GGLDKEFSDIFRRAFASRVFPPEIVEQMGCKHVKGILLYGPPGCGKTLLARQIGKMLNAR 280

Query: 223 ----VVGSELIQKYLGDGPKLVRQVFQVAEEHAPS--------IMFTDEIEAIGTKRYDS 270
               V G E++ KY+G+    +R++F  AEE            I+  DEI+AI  +R   
Sbjct: 281 EPKVVNGPEILNKYVGESEANIRKLFADAEEEQRRLGANSGLHIIIFDEIDAICKQR--G 338

Query: 271 NSGGEREIQQTMLELELLNQLGGFDSREDVKVIMATKQVETLDPVLIRPGRIDKKIEFHL 330
           +  G   +  T++  +LL+++ G +   ++ VI  T + + +D  L+RPGR++ K+E  L
Sbjct: 339 SMAGSTGVHDTVVN-QLLSKIDGVEQLNNILVIGMTNRPDLIDEALLRPGRLEVKMEIGL 397

Query: 331 PDEKTKKHIFQIHTSRM----TLANDVTLDDLIMAKDDFSGADIKAICTEAGLMALREHR 386
           PDEK +  I  IHT+RM     L+ DV + +L +   +FSGA+++ +   A   A+  H 
Sbjct: 398 PDEKGRLQILHIHTARMRGHQLLSADVDIKELAVETKNFSGAELEGLVRAAQSTAMNRHI 457

Query: 387 MKAT 390
             +T
Sbjct: 458 KAST 461


>gi|62177112 katanin p60 subunit A-like 1 [Homo sapiens]
          Length = 490

 Score =  108 bits (269), Expect = 1e-23
 Identities = 76/242 (31%), Positives = 129/242 (53%), Gaps = 28/242 (11%)

Query: 163 VEKAPQETYVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTA---- 218
           V + P   + +   L+   + ++E++ LP+  P++++ +  +P KGV++ GPPGT     
Sbjct: 199 VSRNPSIHWDDIADLEEAKKLLREAVVLPMWMPDFFKGI-RRPWKGVLMVGPPGTGKTML 257

Query: 219 ----------TFLRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRY 268
                     TF  V  S L  KY G+  KLVR +F++A  +AP+ +F DEI++I ++R 
Sbjct: 258 AKAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRRG 317

Query: 269 DSNSGGEREIQQTMLELELLNQLGGF-------DSREDVKVIMATKQVETLDPVLIRPGR 321
            S+   E E  +  ++ ELL Q+ G        D  + V V+ AT     +D  L R  R
Sbjct: 318 TSD---EHEASR-RVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDEALRR--R 371

Query: 322 IDKKIEFHLPDEKTKKHIFQIHTSRMTLANDVTLDDLIMAKDDFSGADIKAICTEAGLMA 381
           ++K+I   LP  K +  + +I+   + L  D+ L+D+    + +SGADI  +C +A LMA
Sbjct: 372 LEKRIYIPLPTAKGRAELLKINLREVELDPDIQLEDIAEKIEGYSGADITNVCRDASLMA 431

Query: 382 LR 383
           +R
Sbjct: 432 MR 433


>gi|14149767 katanin p60 subunit A-like 1 [Homo sapiens]
          Length = 490

 Score =  108 bits (269), Expect = 1e-23
 Identities = 76/242 (31%), Positives = 129/242 (53%), Gaps = 28/242 (11%)

Query: 163 VEKAPQETYVNTGGLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTA---- 218
           V + P   + +   L+   + ++E++ LP+  P++++ +  +P KGV++ GPPGT     
Sbjct: 199 VSRNPSIHWDDIADLEEAKKLLREAVVLPMWMPDFFKGI-RRPWKGVLMVGPPGTGKTML 257

Query: 219 ----------TFLRVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRY 268
                     TF  V  S L  KY G+  KLVR +F++A  +AP+ +F DEI++I ++R 
Sbjct: 258 AKAVATECGTTFFNVSSSTLTSKYRGESEKLVRLLFEMARFYAPTTIFIDEIDSICSRRG 317

Query: 269 DSNSGGEREIQQTMLELELLNQLGGF-------DSREDVKVIMATKQVETLDPVLIRPGR 321
            S+   E E  +  ++ ELL Q+ G        D  + V V+ AT     +D  L R  R
Sbjct: 318 TSD---EHEASR-RVKSELLIQMDGVGGALENDDPSKMVMVLAATNFPWDIDEALRR--R 371

Query: 322 IDKKIEFHLPDEKTKKHIFQIHTSRMTLANDVTLDDLIMAKDDFSGADIKAICTEAGLMA 381
           ++K+I   LP  K +  + +I+   + L  D+ L+D+    + +SGADI  +C +A LMA
Sbjct: 372 LEKRIYIPLPTAKGRAELLKINLREVELDPDIQLEDIAEKIEGYSGADITNVCRDASLMA 431

Query: 382 LR 383
           +R
Sbjct: 432 MR 433


>gi|226371754 katanin p60 subunit A-like 2 [Homo sapiens]
          Length = 466

 Score =  105 bits (263), Expect = 6e-23
 Identities = 72/230 (31%), Positives = 123/230 (53%), Gaps = 26/230 (11%)

Query: 176 GLDNQIQEIKESMELPLPHPEYYEEMGTKPPKGVILCGPPGTA--------------TFL 221
           GLD   Q +KE++  P+ +P+ +  +   P KG++L GPPGT               TF 
Sbjct: 186 GLDAAKQLVKEAVVYPIRYPQLFTGI-LSPWKGLLLYGPPGTGKTLLAKAVATECKTTFF 244

Query: 222 RVVGSELIQKYLGDGPKLVRQVFQVAEEHAPSIMFTDEIEAIGTKRYDSNSGGEREIQQT 281
            +  S ++ K+ GD  KLVR +F++A  HAPS +F DE+E++ ++R  + SGGE E    
Sbjct: 245 NISASTIVSKWRGDSEKLVRVLFELARYHAPSTIFLDELESVMSQR-GTASGGEHE-GSL 302

Query: 282 MLELELLNQLGGFDSREDVKVIMATKQVE-TLDPVLIRPGRIDKKIEFHLPDEKTKKHIF 340
            ++ ELL Q+ G    ED+  ++A   +   LD  ++R  R++K+I   LP  + ++ + 
Sbjct: 303 RMKTELLVQMDGLARSEDLVFVLAASNLPWELDCAMLR--RLEKRILVDLPSREARQAMI 360

Query: 341 -----QIHTSR-MTLANDVTLDDLIMAKDDFSGADIKAICTEAGLMALRE 384
                 +  SR + L  ++    L    + +SG+DIK +C EA +  +R+
Sbjct: 361 YHWLPPVSKSRALELHTELEYSVLSQETEGYSGSDIKLVCREAAMRPVRK 410


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.135    0.375 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,715,948
Number of Sequences: 37866
Number of extensions: 733837
Number of successful extensions: 2355
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 47
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 2196
Number of HSP's gapped (non-prelim): 78
length of query: 415
length of database: 18,247,518
effective HSP length: 105
effective length of query: 310
effective length of database: 14,271,588
effective search space: 4424192280
effective search space used: 4424192280
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.