BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens] (1388 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens] 2873 0.0 gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Ho... 691 0.0 gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Ho... 691 0.0 gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Ho... 691 0.0 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 413 e-115 gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 411 e-114 gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 408 e-113 gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 407 e-113 gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 406 e-113 gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 406 e-113 gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s... 398 e-110 gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s... 395 e-109 gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa... 392 e-108 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 376 e-104 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 376 e-104 gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 374 e-103 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 367 e-101 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 367 e-101 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 366 e-101 gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] 365 e-100 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 363 e-100 gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 361 2e-99 gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] 359 9e-99 gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] 358 2e-98 gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 357 6e-98 gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 352 1e-96 gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s... 350 7e-96 gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s... 350 7e-96 gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s... 350 7e-96 gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s... 350 7e-96 >gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens] Length = 1388 Score = 2873 bits (7447), Expect = 0.0 Identities = 1388/1388 (100%), Positives = 1388/1388 (100%) Query: 1 MAPRRNNGQCWCLLMLLSVSTPLPAVTQTRGATETASQGHLDLTQLIGVPLPSSVSFVTG 60 MAPRRNNGQCWCLLMLLSVSTPLPAVTQTRGATETASQGHLDLTQLIGVPLPSSVSFVTG Sbjct: 1 MAPRRNNGQCWCLLMLLSVSTPLPAVTQTRGATETASQGHLDLTQLIGVPLPSSVSFVTG 60 Query: 61 YGGFPAYSFGPGANVGRPARTLIPSTFFRDFAISVVVKPSSTRGGVLFAITDAFQKVIYL 120 YGGFPAYSFGPGANVGRPARTLIPSTFFRDFAISVVVKPSSTRGGVLFAITDAFQKVIYL Sbjct: 61 YGGFPAYSFGPGANVGRPARTLIPSTFFRDFAISVVVKPSSTRGGVLFAITDAFQKVIYL 120 Query: 121 GLRLSGVEDGHQRIILYYTEPGSHVSQEAAAFSVPVMTHRWNRFAMIVQGEEVTLLVNCE 180 GLRLSGVEDGHQRIILYYTEPGSHVSQEAAAFSVPVMTHRWNRFAMIVQGEEVTLLVNCE Sbjct: 121 GLRLSGVEDGHQRIILYYTEPGSHVSQEAAAFSVPVMTHRWNRFAMIVQGEEVTLLVNCE 180 Query: 181 EHSRIPFQRSSQALAFESSAGIFMGNAGATGLERFTGSLQQLTVHPDPRTPEELCDPEES 240 EHSRIPFQRSSQALAFESSAGIFMGNAGATGLERFTGSLQQLTVHPDPRTPEELCDPEES Sbjct: 181 EHSRIPFQRSSQALAFESSAGIFMGNAGATGLERFTGSLQQLTVHPDPRTPEELCDPEES 240 Query: 241 SASGETSGLQEADGVAEILEAVTYTQASPKEAKVEPINTPPTPSSPFEDMELSGEPVPEG 300 SASGETSGLQEADGVAEILEAVTYTQASPKEAKVEPINTPPTPSSPFEDMELSGEPVPEG Sbjct: 241 SASGETSGLQEADGVAEILEAVTYTQASPKEAKVEPINTPPTPSSPFEDMELSGEPVPEG 300 Query: 301 TLETTNMSIIQHSSPKQGSGEILNDTLEGVHSVDGDPITDSGSGAGAFLDIAEEKNLAAT 360 TLETTNMSIIQHSSPKQGSGEILNDTLEGVHSVDGDPITDSGSGAGAFLDIAEEKNLAAT Sbjct: 301 TLETTNMSIIQHSSPKQGSGEILNDTLEGVHSVDGDPITDSGSGAGAFLDIAEEKNLAAT 360 Query: 361 AAGLAEVPISTAGEAEASSVPTGGPTLSMSTENPEEGVTPGPDNEERLAATAAGEAEALA 420 AAGLAEVPISTAGEAEASSVPTGGPTLSMSTENPEEGVTPGPDNEERLAATAAGEAEALA Sbjct: 361 AAGLAEVPISTAGEAEASSVPTGGPTLSMSTENPEEGVTPGPDNEERLAATAAGEAEALA 420 Query: 421 SMPGEVEASGVAPGELDLSMSAQSLGEEATVGPSSEDSLTTAAAATEVSLSTFEDEEASG 480 SMPGEVEASGVAPGELDLSMSAQSLGEEATVGPSSEDSLTTAAAATEVSLSTFEDEEASG Sbjct: 421 SMPGEVEASGVAPGELDLSMSAQSLGEEATVGPSSEDSLTTAAAATEVSLSTFEDEEASG 480 Query: 481 VPTDGLAPLTATMAPERAVTSGPGDEEDLAAATTEEPLITAGGEESGSPPPDGPPLPLPT 540 VPTDGLAPLTATMAPERAVTSGPGDEEDLAAATTEEPLITAGGEESGSPPPDGPPLPLPT Sbjct: 481 VPTDGLAPLTATMAPERAVTSGPGDEEDLAAATTEEPLITAGGEESGSPPPDGPPLPLPT 540 Query: 541 VAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWG 600 VAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWG Sbjct: 541 VAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWG 600 Query: 601 SDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPP 660 SDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPP Sbjct: 601 SDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPP 660 Query: 661 GPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPP 720 GPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPP Sbjct: 661 GPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPP 720 Query: 721 GPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGM 780 GPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGM Sbjct: 721 GPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGM 780 Query: 781 DGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPR 840 DGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPR Sbjct: 781 DGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPR 840 Query: 841 GPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPG 900 GPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPG Sbjct: 841 GPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPG 900 Query: 901 HKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIP 960 HKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIP Sbjct: 901 HKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIP 960 Query: 961 VRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLR 1020 VRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLR Sbjct: 961 VRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLR 1020 Query: 1021 HFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGA 1080 HFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGA Sbjct: 1021 HFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGA 1080 Query: 1081 PGLPGPPGFGRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNLVTAFSN 1140 PGLPGPPGFGRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNLVTAFSN Sbjct: 1081 PGLPGPPGFGRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNLVTAFSN 1140 Query: 1141 MDDMLQKAHLVIEGTFIYLRDSTEFFIRVRDGWKKLQLGELIPIPADSPPPPALSSNPHQ 1200 MDDMLQKAHLVIEGTFIYLRDSTEFFIRVRDGWKKLQLGELIPIPADSPPPPALSSNPHQ Sbjct: 1141 MDDMLQKAHLVIEGTFIYLRDSTEFFIRVRDGWKKLQLGELIPIPADSPPPPALSSNPHQ 1200 Query: 1201 LLPPPNPISSANYEKPALHLAALNMPFSGDIRADFQCFKQARAAGLLSTYRAFLSSHLQD 1260 LLPPPNPISSANYEKPALHLAALNMPFSGDIRADFQCFKQARAAGLLSTYRAFLSSHLQD Sbjct: 1201 LLPPPNPISSANYEKPALHLAALNMPFSGDIRADFQCFKQARAAGLLSTYRAFLSSHLQD 1260 Query: 1261 LSTIVRKAERYSLPIVNLKGQVLFNNWDSIFSGHGGQFNMHIPIYSFDGRDIMTDPSWPQ 1320 LSTIVRKAERYSLPIVNLKGQVLFNNWDSIFSGHGGQFNMHIPIYSFDGRDIMTDPSWPQ Sbjct: 1261 LSTIVRKAERYSLPIVNLKGQVLFNNWDSIFSGHGGQFNMHIPIYSFDGRDIMTDPSWPQ 1320 Query: 1321 KVIWHGSSPHGVRLVDNYCEAWRTADTAVTGLASPLSTGKILDQKAYSCANRLIVLCIEN 1380 KVIWHGSSPHGVRLVDNYCEAWRTADTAVTGLASPLSTGKILDQKAYSCANRLIVLCIEN Sbjct: 1321 KVIWHGSSPHGVRLVDNYCEAWRTADTAVTGLASPLSTGKILDQKAYSCANRLIVLCIEN 1380 Query: 1381 SFMTDARK 1388 SFMTDARK Sbjct: 1381 SFMTDARK 1388 >gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Homo sapiens] Length = 1751 Score = 691 bits (1784), Expect = 0.0 Identities = 425/1020 (41%), Positives = 522/1020 (51%), Gaps = 206/1020 (20%) Query: 517 PLITAGGEESGSPPPDGPPLPLPTVAPERWITPAQ------------------REHVGMK 558 PL AG P P GPP P P R TP + + G Sbjct: 789 PLGPAGPALQTVPGPQGPPGP-----PGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTP 843 Query: 559 GQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLR 618 G GPKG+KGD G GPP P GP GP G L + GSG G G + LR Sbjct: 844 GDVGPKGDKGDPGVGERGPPGPQGPPGPP-GPSFRHDKLTFIDMEGSGFG---GDLEALR 899 Query: 619 GP---PGPPGPPGLPGIPGKPG------TDVF--MGPPGSPGEDGPAGEPGPPGPEGQPG 667 GP PGPPGPPG+PG+PG+PG +DV G PG PG +GP G PG PGP G PG Sbjct: 900 GPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPG 959 Query: 668 VDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPG 727 +G PG G+KG+ G G+ G KG G G G G+ G AG PG GPPGPPGPPG Sbjct: 960 REGP---PGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPG 1016 Query: 728 PPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGL---------------------- 765 PPGPG + GF+D EGSG P GL Sbjct: 1017 PPGPG--LPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGAD 1074 Query: 766 --------------------KGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSL 805 KG++G RG KG+ G DG G PGP GPPG + +S Sbjct: 1075 GVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQD 1134 Query: 806 INITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPG 865 ++ + PGP+G PG GFPGP GPKG+ G G G G +GEKGEPG Sbjct: 1135 GSV-------------LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPG 1181 Query: 866 AILTEDI----PLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKG 921 +I + D P ++ G KGEPG G PGP G PG+KGE G PGRPGRPG+NGLKG Sbjct: 1182 SIFSPDGGALGPAQK--GAKGEPGFRGPPGPYGR---PGYKGEIGFPGRPGRPGMNGLKG 1236 Query: 922 TKGDPGVI-----MQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGS 976 KG+PG M+G PG PGPPGPPGPPG + +++ PG Sbjct: 1237 EKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVF------------AESSRPGP 1284 Query: 977 PELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGP-PLDLAYLRHFLNNLKGENGDKGF 1035 P G G+ G PG KG KG+ G GPPG P D L + KG+ GD G Sbjct: 1285 P---------GLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQ 1335 Query: 1036 KGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGP-----PGAPGLPGPPGFG 1090 KGE+GE G G F S PG PG PGP G G + GP+G PG PG GPPG G Sbjct: 1336 KGERGEPG--GGGFFGSSLPGPPGPPGPRGYPG--IPGPKGESIRGQPGPPGPQGPPGIG 1391 Query: 1091 RPGDPGPPGPPGPPGPPAILG------AAVALPGPPGPPGQPGLPGSRNLVTAFSNMDDM 1144 G GPPGPPGPPGPP+ G + PGPPGPPG PG G+ + V ++ M Sbjct: 1392 YEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAM 1451 Query: 1145 LQKAHLVIEGTFIYLRDSTEFFIRVRDGWKKLQLGELIPIP--------ADSPPPPAL-S 1195 L + H V EG I++ + E ++RV++G++K+QL P+P A PP L Sbjct: 1452 LGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHD 1511 Query: 1196 SNPH----------------------QLLPPPNPISSANYE------------------- 1214 SNP+ LP P P A + Sbjct: 1512 SNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHSH 1571 Query: 1215 ---KPALHLAALNMPFSGDIR----ADFQCFKQARAAGLLSTYRAFLSSHLQDLSTIVRK 1267 +P LHL ALN P SG +R ADFQCF+QARA GL T+RAFLSS LQDL +IVR+ Sbjct: 1572 RDFQPVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRR 1631 Query: 1268 AERYSLPIVNLKGQVLFNNWDSIFSGHGGQFNMHIPIYSFDGRDIMTDPSWPQKVIWHGS 1327 A+R ++PIVNLK ++LF +W+++FSG G I+SFDG+D++ P+WPQK +WHGS Sbjct: 1632 ADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKDVLRHPTWPQKSVWHGS 1691 Query: 1328 SPHGVRLVDNYCEAWRTADTAVTGLASPLSTGKILDQKAYSCANRLIVLCIENSFMTDAR 1387 P+G RL ++YCE WRT + TG AS L G++L Q A SC + IVLCIENSFMT ++ Sbjct: 1692 DPNGRRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHHAYIVLCIENSFMTASK 1751 Score = 414 bits (1063), Expect = e-115 Identities = 350/1047 (33%), Positives = 444/1047 (42%), Gaps = 166/1047 (15%) Query: 32 ATETASQGHLDLTQLIGVPLPSSVSFVTGYGGFPAYSFGPGANVGRPARTLIPSTFFRDF 91 A E S+ + L QL+G P P V+ AY FGP AN G+ AR PS FFRDF Sbjct: 449 AAERISE-EVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDANSGQVARYHFPSLFFRDF 507 Query: 92 AISVVVKPSSTRGGVLFAITDAFQKVIYLGLRLSGVEDGHQRIILYYTEPGSHVSQEAAA 151 ++ ++P++ GVLFAITD+ Q ++ LG++LSGV+DGHQ I L YTEPG+ + AA+ Sbjct: 508 SLLFHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQDISLLYTEPGAGQTHTAAS 567 Query: 152 FSVPVMTHRWNRFAMIVQGEEVTLLVNCEEHSRIPFQRSSQALAFESSAGIFMGNAGATG 211 F +P +W A+ V G V L V+CEE R+P RSS+ L E AG+F+ AG Sbjct: 568 FRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRGLELEPGAGLFVAQAGGAD 627 Query: 212 LERFTGSLQQLTVHPDPRTPEELCDPEE----SSASGET-SGLQEADGVAEILEAVTYTQ 266 ++F G + +L V DP+ C EE ASG++ SGL +A E+L T Sbjct: 628 PDKFQGVIAELKVRRDPQVSPMHCLDEEGDDSDGASGDSGSGLGDA---RELLREETGAA 684 Query: 267 ASPKEAKVEPINTPP------TPSSPFEDMELSGEPVPEG--TLETTNMSIIQHSSPKQG 318 P+ P+ TPP T S E++E G TL ++ S + Sbjct: 685 LKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDGSVRTP 744 Query: 319 SGEILNDTLEGVHSVDGDPITDSGSGAGAFLDIAEEKNLAATAAGLAEVPISTAGEA-EA 377 G + L+G G P +G + L + P+ AG A + Sbjct: 745 GGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVS-----PLGPAGPALQT 799 Query: 378 SSVPTGGPTLSMSTENPEEGVTPGPDNEERLAATAAGEAEALASMPGEVEASGVAPGELD 437 P G P P PG E+ + PG+V G Sbjct: 800 VPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG--PQGFPGTPGDVGPKG------- 850 Query: 438 LSMSAQSLGEEATVGPSSEDSLTTAAAATEVSLSTFEDEEASGVPTDGLAPLTATMAPE- 496 +GE GP + TF D E SG D L A P Sbjct: 851 -DKGDPGVGERGPPGPQGPPG--PPGPSFRHDKLTFIDMEGSGFGGD----LEALRGPRG 903 Query: 497 -------RAVTSGPGDEEDLAAATTEEPLITAG--GEESGSPPPDGPPLPLPTVAPERWI 547 V PG+ +++ P AG G PP P LP P P R Sbjct: 904 FPGPPGPPGVPGLPGEPGRFGVNSSDVP-GPAGLPGVPGREGPPGFPGLPGPPGPPGREG 962 Query: 548 TPAQR------------EHVGMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGS 595 P + H G KG GP G +G++G L G P P+GP GP G Sbjct: 963 PPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESG--LAGAPGPAGPPGPPGPPGPPGP 1020 Query: 596 GLGWGSDVGSGS-GDLVGSEQLLRGPPGPPGPPGL---PGIPGKP------GTDVFMGPP 645 GL G D GS G + + GP GPPG PGL PG+PG P G D G P Sbjct: 1021 GLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFP 1080 Query: 646 GSPGEDGPAGEPGPP------GPEGQPGVDGATGLPGMKGEKGARGP-------NGSV-- 690 G PG +G AG GP G +G PG DG G PG+ G G GP +GSV Sbjct: 1081 GLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVYVSEQDGSVLS 1139 Query: 691 --GEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPG-----PGCTMGLGFEDTE 743 G +G PG G PGP G KG G G G PGP G G PG G +G + + Sbjct: 1140 VPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAK 1199 Query: 744 GS-------------GSTQLLNEPKLSRPTAAIGLKGEKGDRGPK----GERGMDGASIV 786 G G + P GLKGEKG+ G G RGM G Sbjct: 1200 GEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPP-- 1257 Query: 787 GPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDT 846 GPPGP GPPG SN + PGP GLPG G PGP+G KG+ Sbjct: 1258 GPPGPPGPPGTPVYDSNVFAESSR--------------PGPPGLPGNQGPPGPKGAKGEV 1303 Query: 847 GLPGFPG------------LKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPM- 893 G PG PG +KGE+G++G+ G G++GEPG G G Sbjct: 1304 GPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQ-----------KGERGEPGGGGFFGSSL 1352 Query: 894 -GPKGPPGHKGEFGLPGRPGRP--GLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVI 950 GP GPPG +G G+PG G G G G +G PG+ +G G PGPPGPPGPP Sbjct: 1353 PGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPS--- 1409 Query: 951 NIKGAIFPIPVRPHCKMPVDTAHPGSP 977 FP P R +P PG P Sbjct: 1410 ------FPGPHRQTISVPGPPGPPGPP 1430 Score = 110 bits (274), Expect = 1e-23 Identities = 71/176 (40%), Positives = 82/176 (46%), Gaps = 38/176 (21%) Query: 984 GVKGEKGSWGLPGSKGEKGDQGA---QGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKG 1040 G+KG+KG G+PG G G G+ GPPG P ++ L L+ G +G G G Sbjct: 752 GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPG 811 Query: 1041 EKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGP------PGFGRPGD 1094 G G G PG+PG G+ G+T GPQG PG PG GP PG G G Sbjct: 812 RDG-------TPGRDGEPGDPGEDGKPGDT--GPQGFPGTPGDVGPKGDKGDPGVGERGP 862 Query: 1095 PGPPGPPGPPGPP--------------------AILGAAVALPGPPGPPGQPGLPG 1130 PGP GPPGPPGP L PGPPGPPG PGLPG Sbjct: 863 PGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPG 918 Score = 86.3 bits (212), Expect = 2e-16 Identities = 64/161 (39%), Positives = 70/161 (43%), Gaps = 31/161 (19%) Query: 990 GSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSF 1049 G+ LPGS G+ PG R LKG+ G+ G G G G GS Sbjct: 724 GAQTLPGSDSVSTWDGSVRTPGG-------RVKEGGLKGQKGEPGVPGPPGRAGP-PGSP 775 Query: 1050 LMSGPPGLP---GNPGPAGQKGETVVGPQGPPGAPGLPGPPGF----GRPGDPGPPGPPG 1102 + GPPGLP GPAG +TV GPQGP PG PG G G PGDPG G PG Sbjct: 776 CLPGPPGLPCPVSPLGPAGPALQTVPGPQGP---PGPPGRDGTPGRDGEPGDPGEDGKPG 832 Query: 1103 PPGPPAILGA-------------AVALPGPPGPPGQPGLPG 1130 GP G V GPPGP G PG PG Sbjct: 833 DTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPG 873 Score = 36.2 bits (82), Expect = 0.22 Identities = 32/109 (29%), Positives = 42/109 (38%), Gaps = 18/109 (16%) Query: 1053 GPPGLPGNPGPAGQKGETVVGPQGPPGAPG------------LPGPPGFGRPGDP--GPP 1098 GP L G + G T+ +G P +PG P PP GRP P GP Sbjct: 150 GPLALAGPSSTPQENGTTLWPSRGIPSSPGAHTTEAGTLPAPTPSPPSLGRPWAPLTGPS 209 Query: 1099 GPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNLVTAFSNMDDMLQK 1147 PP G ++ +L G P G P S+ L A + LQ+ Sbjct: 210 VPPPSSGRASL----SSLLGGAPPWGSLQDPDSQGLSPAAAAPSQQLQR 254 Score = 35.0 bits (79), Expect = 0.50 Identities = 30/104 (28%), Positives = 40/104 (38%), Gaps = 22/104 (21%) Query: 1031 GDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPGFG 1090 G + + E+ + + G LPG+ + G +V P G GL G Sbjct: 702 GGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDG-SVRTPGGRVKEGGLKG----- 755 Query: 1091 RPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNL 1134 + G+PG PGPPG GPP G P LPG L Sbjct: 756 QKGEPGVPGPPGRAGPP----------------GSPCLPGPPGL 783 >gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Homo sapiens] Length = 1336 Score = 691 bits (1784), Expect = 0.0 Identities = 425/1020 (41%), Positives = 522/1020 (51%), Gaps = 206/1020 (20%) Query: 517 PLITAGGEESGSPPPDGPPLPLPTVAPERWITPAQ------------------REHVGMK 558 PL AG P P GPP P P R TP + + G Sbjct: 374 PLGPAGPALQTVPGPQGPPGP-----PGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTP 428 Query: 559 GQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLR 618 G GPKG+KGD G GPP P GP GP G L + GSG G G + LR Sbjct: 429 GDVGPKGDKGDPGVGERGPPGPQGPPGPP-GPSFRHDKLTFIDMEGSGFG---GDLEALR 484 Query: 619 GP---PGPPGPPGLPGIPGKPG------TDVF--MGPPGSPGEDGPAGEPGPPGPEGQPG 667 GP PGPPGPPG+PG+PG+PG +DV G PG PG +GP G PG PGP G PG Sbjct: 485 GPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPG 544 Query: 668 VDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPG 727 +G PG G+KG+ G G+ G KG G G G G+ G AG PG GPPGPPGPPG Sbjct: 545 REGP---PGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPG 601 Query: 728 PPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGL---------------------- 765 PPGPG + GF+D EGSG P GL Sbjct: 602 PPGPG--LPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGAD 659 Query: 766 --------------------KGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSL 805 KG++G RG KG+ G DG G PGP GPPG + +S Sbjct: 660 GVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQD 719 Query: 806 INITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPG 865 ++ + PGP+G PG GFPGP GPKG+ G G G G +GEKGEPG Sbjct: 720 GSV-------------LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPG 766 Query: 866 AILTEDI----PLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKG 921 +I + D P ++ G KGEPG G PGP G PG+KGE G PGRPGRPG+NGLKG Sbjct: 767 SIFSPDGGALGPAQK--GAKGEPGFRGPPGPYGR---PGYKGEIGFPGRPGRPGMNGLKG 821 Query: 922 TKGDPGVI-----MQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGS 976 KG+PG M+G PG PGPPGPPGPPG + +++ PG Sbjct: 822 EKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVF------------AESSRPGP 869 Query: 977 PELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGP-PLDLAYLRHFLNNLKGENGDKGF 1035 P G G+ G PG KG KG+ G GPPG P D L + KG+ GD G Sbjct: 870 P---------GLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQ 920 Query: 1036 KGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGP-----PGAPGLPGPPGFG 1090 KGE+GE G G F S PG PG PGP G G + GP+G PG PG GPPG G Sbjct: 921 KGERGEPG--GGGFFGSSLPGPPGPPGPRGYPG--IPGPKGESIRGQPGPPGPQGPPGIG 976 Query: 1091 RPGDPGPPGPPGPPGPPAILG------AAVALPGPPGPPGQPGLPGSRNLVTAFSNMDDM 1144 G GPPGPPGPPGPP+ G + PGPPGPPG PG G+ + V ++ M Sbjct: 977 YEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAM 1036 Query: 1145 LQKAHLVIEGTFIYLRDSTEFFIRVRDGWKKLQLGELIPIP--------ADSPPPPAL-S 1195 L + H V EG I++ + E ++RV++G++K+QL P+P A PP L Sbjct: 1037 LGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHD 1096 Query: 1196 SNPH----------------------QLLPPPNPISSANYE------------------- 1214 SNP+ LP P P A + Sbjct: 1097 SNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHSH 1156 Query: 1215 ---KPALHLAALNMPFSGDIR----ADFQCFKQARAAGLLSTYRAFLSSHLQDLSTIVRK 1267 +P LHL ALN P SG +R ADFQCF+QARA GL T+RAFLSS LQDL +IVR+ Sbjct: 1157 RDFQPVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRR 1216 Query: 1268 AERYSLPIVNLKGQVLFNNWDSIFSGHGGQFNMHIPIYSFDGRDIMTDPSWPQKVIWHGS 1327 A+R ++PIVNLK ++LF +W+++FSG G I+SFDG+D++ P+WPQK +WHGS Sbjct: 1217 ADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKDVLRHPTWPQKSVWHGS 1276 Query: 1328 SPHGVRLVDNYCEAWRTADTAVTGLASPLSTGKILDQKAYSCANRLIVLCIENSFMTDAR 1387 P+G RL ++YCE WRT + TG AS L G++L Q A SC + IVLCIENSFMT ++ Sbjct: 1277 DPNGRRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHHAYIVLCIENSFMTASK 1336 Score = 417 bits (1071), Expect = e-116 Identities = 354/1065 (33%), Positives = 450/1065 (42%), Gaps = 167/1065 (15%) Query: 16 LLSVSTPLPAVTQTRGATETASQ--GHLDLTQLIGVPLPSSVSFVTGYGGFPAYSFGPGA 73 LL V PL + R A+ + + L QL+G P P V+ AY FGP A Sbjct: 15 LLDVLAPLVLLLGVRAASAEPERISEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDA 74 Query: 74 NVGRPARTLIPSTFFRDFAISVVVKPSSTRGGVLFAITDAFQKVIYLGLRLSGVEDGHQR 133 N G+ AR PS FFRDF++ ++P++ GVLFAITD+ Q ++ LG++LSGV+DGHQ Sbjct: 75 NSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQD 134 Query: 134 IILYYTEPGSHVSQEAAAFSVPVMTHRWNRFAMIVQGEEVTLLVNCEEHSRIPFQRSSQA 193 I L YTEPG+ + AA+F +P +W A+ V G V L V+CEE R+P RSS+ Sbjct: 135 ISLLYTEPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRG 194 Query: 194 LAFESSAGIFMGNAGATGLERFTGSLQQLTVHPDPRTPEELCDPEE----SSASGET-SG 248 L E AG+F+ AG ++F G + +L V DP+ C EE ASG++ SG Sbjct: 195 LELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDSDGASGDSGSG 254 Query: 249 LQEADGVAEILEAVTYTQASPKEAKVEPINTPP------TPSSPFEDMELSGEPVPEG-- 300 L +A E+L T P+ P+ TPP T S E++E G Sbjct: 255 LGDA---RELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQ 311 Query: 301 TLETTNMSIIQHSSPKQGSGEILNDTLEGVHSVDGDPITDSGSGAGAFLDIAEEKNLAAT 360 TL ++ S + G + L+G G P +G + L Sbjct: 312 TLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCP 371 Query: 361 AAGLAEVPISTAGEA-EASSVPTGGPTLSMSTENPEEGVTPGPDNEERLAATAAGEAEAL 419 + P+ AG A + P G P P PG E+ + Sbjct: 372 VS-----PLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG--PQGF 424 Query: 420 ASMPGEVEASGVAPGELDLSMSAQSLGEEATVGPSSEDSLTTAAAATEVSLSTFEDEEAS 479 PG+V G +GE GP + TF D E S Sbjct: 425 PGTPGDVGPKG--------DKGDPGVGERGPPGPQGPPG--PPGPSFRHDKLTFIDMEGS 474 Query: 480 GVPTDGLAPLTATMAPE--------RAVTSGPGDEEDLAAATTEEPLITAG--GEESGSP 529 G D L A P V PG+ +++ P AG G Sbjct: 475 GFGGD----LEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVP-GPAGLPGVPGREG 529 Query: 530 PPDGPPLPLPTVAPERWITPAQR------------EHVGMKGQAGPKGEKGDAGEELPGP 577 PP P LP P P R P + H G KG GP G +G++G L G Sbjct: 530 PPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESG--LAGA 587 Query: 578 PEPSGPVGPTAGAEAEGSGLGWGSDVGSGS-GDLVGSEQLLRGPPGPPGPPGL---PGIP 633 P P+GP GP G GL G D GS G + + GP GPPG PGL PG+P Sbjct: 588 PGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVP 647 Query: 634 GKP------GTDVFMGPPGSPGEDGPAGEPGPP------GPEGQPGVDGATGLPGMKGEK 681 G P G D G PG PG +G AG GP G +G PG DG G PG+ G Sbjct: 648 GLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPP 706 Query: 682 GARGP-------NGSV----GEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPG 730 G GP +GSV G +G PG G PGP G KG G G G PGP G G PG Sbjct: 707 GPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPG 766 Query: 731 -----PGCTMGLGFEDTEGS-------------GSTQLLNEPKLSRPTAAIGLKGEKGDR 772 G +G + +G G + P GLKGEKG+ Sbjct: 767 SIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEP 826 Query: 773 GPK----GERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPD 828 G G RGM G GPPGP GPPG SN + PGP Sbjct: 827 GDASLGFGMRGMPGPP--GPPGPPGPPGTPVYDSNVFAESSR--------------PGPP 870 Query: 829 GLPGLPGFPGPRGPKGDTGLPGFPG------------LKGEQGEKGEPGAILTEDIPLER 876 GLPG G PGP+G KG+ G PG PG +KGE+G++G+ G Sbjct: 871 GLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQ---------- 920 Query: 877 LMGKKGEPGMHGAPGPM--GPKGPPGHKGEFGLPGRPGRP--GLNGLKGTKGDPGVIMQG 932 G++GEPG G G GP GPPG +G G+PG G G G G +G PG+ +G Sbjct: 921 -KGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEG 979 Query: 933 PPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSP 977 G PGPPGPPGPP FP P R +P PG P Sbjct: 980 RQGPPGPPGPPGPPS---------FPGPHRQTISVPGPPGPPGPP 1015 Score = 110 bits (274), Expect = 1e-23 Identities = 71/176 (40%), Positives = 82/176 (46%), Gaps = 38/176 (21%) Query: 984 GVKGEKGSWGLPGSKGEKGDQGA---QGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKG 1040 G+KG+KG G+PG G G G+ GPPG P ++ L L+ G +G G G Sbjct: 337 GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPG 396 Query: 1041 EKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGP------PGFGRPGD 1094 G G G PG+PG G+ G+T GPQG PG PG GP PG G G Sbjct: 397 RDG-------TPGRDGEPGDPGEDGKPGDT--GPQGFPGTPGDVGPKGDKGDPGVGERGP 447 Query: 1095 PGPPGPPGPPGPP--------------------AILGAAVALPGPPGPPGQPGLPG 1130 PGP GPPGPPGP L PGPPGPPG PGLPG Sbjct: 448 PGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPG 503 Score = 86.3 bits (212), Expect = 2e-16 Identities = 64/161 (39%), Positives = 70/161 (43%), Gaps = 31/161 (19%) Query: 990 GSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSF 1049 G+ LPGS G+ PG R LKG+ G+ G G G G GS Sbjct: 309 GAQTLPGSDSVSTWDGSVRTPGG-------RVKEGGLKGQKGEPGVPGPPGRAGP-PGSP 360 Query: 1050 LMSGPPGLP---GNPGPAGQKGETVVGPQGPPGAPGLPGPPGF----GRPGDPGPPGPPG 1102 + GPPGLP GPAG +TV GPQGP PG PG G G PGDPG G PG Sbjct: 361 CLPGPPGLPCPVSPLGPAGPALQTVPGPQGP---PGPPGRDGTPGRDGEPGDPGEDGKPG 417 Query: 1103 PPGPPAILGA-------------AVALPGPPGPPGQPGLPG 1130 GP G V GPPGP G PG PG Sbjct: 418 DTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPG 458 Score = 35.0 bits (79), Expect = 0.50 Identities = 30/104 (28%), Positives = 40/104 (38%), Gaps = 22/104 (21%) Query: 1031 GDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPGFG 1090 G + + E+ + + G LPG+ + G +V P G GL G Sbjct: 287 GGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDG-SVRTPGGRVKEGGLKG----- 340 Query: 1091 RPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNL 1134 + G+PG PGPPG GPP G P LPG L Sbjct: 341 QKGEPGVPGPPGRAGPP----------------GSPCLPGPPGL 368 >gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Homo sapiens] Length = 1516 Score = 691 bits (1784), Expect = 0.0 Identities = 425/1020 (41%), Positives = 522/1020 (51%), Gaps = 206/1020 (20%) Query: 517 PLITAGGEESGSPPPDGPPLPLPTVAPERWITPAQ------------------REHVGMK 558 PL AG P P GPP P P R TP + + G Sbjct: 554 PLGPAGPALQTVPGPQGPPGP-----PGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTP 608 Query: 559 GQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLR 618 G GPKG+KGD G GPP P GP GP G L + GSG G G + LR Sbjct: 609 GDVGPKGDKGDPGVGERGPPGPQGPPGPP-GPSFRHDKLTFIDMEGSGFG---GDLEALR 664 Query: 619 GP---PGPPGPPGLPGIPGKPG------TDVF--MGPPGSPGEDGPAGEPGPPGPEGQPG 667 GP PGPPGPPG+PG+PG+PG +DV G PG PG +GP G PG PGP G PG Sbjct: 665 GPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPG 724 Query: 668 VDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPG 727 +G PG G+KG+ G G+ G KG G G G G+ G AG PG GPPGPPGPPG Sbjct: 725 REGP---PGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPG 781 Query: 728 PPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGL---------------------- 765 PPGPG + GF+D EGSG P GL Sbjct: 782 PPGPG--LPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGAD 839 Query: 766 --------------------KGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSL 805 KG++G RG KG+ G DG G PGP GPPG + +S Sbjct: 840 GVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQD 899 Query: 806 INITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPG 865 ++ + PGP+G PG GFPGP GPKG+ G G G G +GEKGEPG Sbjct: 900 GSV-------------LSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPG 946 Query: 866 AILTEDI----PLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKG 921 +I + D P ++ G KGEPG G PGP G PG+KGE G PGRPGRPG+NGLKG Sbjct: 947 SIFSPDGGALGPAQK--GAKGEPGFRGPPGPYGR---PGYKGEIGFPGRPGRPGMNGLKG 1001 Query: 922 TKGDPGVI-----MQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGS 976 KG+PG M+G PG PGPPGPPGPPG + +++ PG Sbjct: 1002 EKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVF------------AESSRPGP 1049 Query: 977 PELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGP-PLDLAYLRHFLNNLKGENGDKGF 1035 P G G+ G PG KG KG+ G GPPG P D L + KG+ GD G Sbjct: 1050 P---------GLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQ 1100 Query: 1036 KGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGP-----PGAPGLPGPPGFG 1090 KGE+GE G G F S PG PG PGP G G + GP+G PG PG GPPG G Sbjct: 1101 KGERGEPG--GGGFFGSSLPGPPGPPGPRGYPG--IPGPKGESIRGQPGPPGPQGPPGIG 1156 Query: 1091 RPGDPGPPGPPGPPGPPAILG------AAVALPGPPGPPGQPGLPGSRNLVTAFSNMDDM 1144 G GPPGPPGPPGPP+ G + PGPPGPPG PG G+ + V ++ M Sbjct: 1157 YEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAM 1216 Query: 1145 LQKAHLVIEGTFIYLRDSTEFFIRVRDGWKKLQLGELIPIP--------ADSPPPPAL-S 1195 L + H V EG I++ + E ++RV++G++K+QL P+P A PP L Sbjct: 1217 LGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHD 1276 Query: 1196 SNPH----------------------QLLPPPNPISSANYE------------------- 1214 SNP+ LP P P A + Sbjct: 1277 SNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHSH 1336 Query: 1215 ---KPALHLAALNMPFSGDIR----ADFQCFKQARAAGLLSTYRAFLSSHLQDLSTIVRK 1267 +P LHL ALN P SG +R ADFQCF+QARA GL T+RAFLSS LQDL +IVR+ Sbjct: 1337 RDFQPVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRR 1396 Query: 1268 AERYSLPIVNLKGQVLFNNWDSIFSGHGGQFNMHIPIYSFDGRDIMTDPSWPQKVIWHGS 1327 A+R ++PIVNLK ++LF +W+++FSG G I+SFDG+D++ P+WPQK +WHGS Sbjct: 1397 ADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKDVLRHPTWPQKSVWHGS 1456 Query: 1328 SPHGVRLVDNYCEAWRTADTAVTGLASPLSTGKILDQKAYSCANRLIVLCIENSFMTDAR 1387 P+G RL ++YCE WRT + TG AS L G++L Q A SC + IVLCIENSFMT ++ Sbjct: 1457 DPNGRRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHHAYIVLCIENSFMTASK 1516 Score = 414 bits (1063), Expect = e-115 Identities = 351/1057 (33%), Positives = 448/1057 (42%), Gaps = 166/1057 (15%) Query: 22 PLPAVTQTRGATETASQGHLDLTQLIGVPLPSSVSFVTGYGGFPAYSFGPGANVGRPART 81 PL + ++E S+ + L QL+G P P V+ AY FGP AN G+ AR Sbjct: 204 PLTGPSVPPPSSERISE-EVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDANSGQVARY 262 Query: 82 LIPSTFFRDFAISVVVKPSSTRGGVLFAITDAFQKVIYLGLRLSGVEDGHQRIILYYTEP 141 PS FFRDF++ ++P++ GVLFAITD+ Q ++ LG++LSGV+DGHQ I L YTEP Sbjct: 263 HFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQDISLLYTEP 322 Query: 142 GSHVSQEAAAFSVPVMTHRWNRFAMIVQGEEVTLLVNCEEHSRIPFQRSSQALAFESSAG 201 G+ + AA+F +P +W A+ V G V L V+CEE R+P RSS+ L E AG Sbjct: 323 GAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRGLELEPGAG 382 Query: 202 IFMGNAGATGLERFTGSLQQLTVHPDPRTPEELCDPEE----SSASGET-SGLQEADGVA 256 +F+ AG ++F G + +L V DP+ C EE ASG++ SGL +A Sbjct: 383 LFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDSDGASGDSGSGLGDA---R 439 Query: 257 EILEAVTYTQASPKEAKVEPINTPP------TPSSPFEDMELSGEPVPEG--TLETTNMS 308 E+L T P+ P+ TPP T S E++E G TL ++ Sbjct: 440 ELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSV 499 Query: 309 IIQHSSPKQGSGEILNDTLEGVHSVDGDPITDSGSGAGAFLDIAEEKNLAATAAGLAEVP 368 S + G + L+G G P +G + L + P Sbjct: 500 STWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVS-----P 554 Query: 369 ISTAGEA-EASSVPTGGPTLSMSTENPEEGVTPGPDNEERLAATAAGEAEALASMPGEVE 427 + AG A + P G P P PG E+ + PG+V Sbjct: 555 LGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG--PQGFPGTPGDVG 612 Query: 428 ASGVAPGELDLSMSAQSLGEEATVGPSSEDSLTTAAAATEVSLSTFEDEEASGVPTDGLA 487 G +GE GP + TF D E SG D Sbjct: 613 PKG--------DKGDPGVGERGPPGPQGPPG--PPGPSFRHDKLTFIDMEGSGFGGD--- 659 Query: 488 PLTATMAPE--------RAVTSGPGDEEDLAAATTEEPLITAG--GEESGSPPPDGPPLP 537 L A P V PG+ +++ P AG G PP P LP Sbjct: 660 -LEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVP-GPAGLPGVPGREGPPGFPGLP 717 Query: 538 LPTVAPERWITPAQR------------EHVGMKGQAGPKGEKGDAGEELPGPPEPSGPVG 585 P P R P + H G KG GP G +G++G L G P P+GP G Sbjct: 718 GPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESG--LAGAPGPAGPPG 775 Query: 586 PTAGAEAEGSGLGWGSDVGSGS-GDLVGSEQLLRGPPGPPGPPGL---PGIPGKP----- 636 P G GL G D GS G + + GP GPPG PGL PG+PG P Sbjct: 776 PPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGE 835 Query: 637 -GTDVFMGPPGSPGEDGPAGEPGPP------GPEGQPGVDGATGLPGMKGEKGARGP--- 686 G D G PG PG +G AG GP G +G PG DG G PG+ G G GP Sbjct: 836 VGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDG-VGQPGLPGPPGPPGPVVY 894 Query: 687 ----NGSV----GEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPG-----PGC 733 +GSV G +G PG G PGP G KG G G G PGP G G PG G Sbjct: 895 VSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGG 954 Query: 734 TMGLGFEDTEGS-------------GSTQLLNEPKLSRPTAAIGLKGEKGDRGPK----G 776 +G + +G G + P GLKGEKG+ G G Sbjct: 955 ALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFG 1014 Query: 777 ERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGF 836 RGM G GPPGP GPPG SN + PGP GLPG G Sbjct: 1015 MRGMPGPP--GPPGPPGPPGTPVYDSNVFAESSR--------------PGPPGLPGNQGP 1058 Query: 837 PGPRGPKGDTGLPGFPG------------LKGEQGEKGEPGAILTEDIPLERLMGKKGEP 884 PGP+G KG+ G PG PG +KGE+G++G+ G G++GEP Sbjct: 1059 PGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQ-----------KGERGEP 1107 Query: 885 GMHGAPGPM--GPKGPPGHKGEFGLPGRPGRP--GLNGLKGTKGDPGVIMQGPPGLPGPP 940 G G G GP GPPG +G G+PG G G G G +G PG+ +G G PGPP Sbjct: 1108 GGGGFFGSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPP 1167 Query: 941 GPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSP 977 GPPGPP FP P R +P PG P Sbjct: 1168 GPPGPPS---------FPGPHRQTISVPGPPGPPGPP 1195 Score = 110 bits (274), Expect = 1e-23 Identities = 71/176 (40%), Positives = 82/176 (46%), Gaps = 38/176 (21%) Query: 984 GVKGEKGSWGLPGSKGEKGDQGA---QGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKG 1040 G+KG+KG G+PG G G G+ GPPG P ++ L L+ G +G G G Sbjct: 517 GLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPG 576 Query: 1041 EKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGP------PGFGRPGD 1094 G G G PG+PG G+ G+T GPQG PG PG GP PG G G Sbjct: 577 RDG-------TPGRDGEPGDPGEDGKPGDT--GPQGFPGTPGDVGPKGDKGDPGVGERGP 627 Query: 1095 PGPPGPPGPPGPP--------------------AILGAAVALPGPPGPPGQPGLPG 1130 PGP GPPGPPGP L PGPPGPPG PGLPG Sbjct: 628 PGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPG 683 Score = 86.3 bits (212), Expect = 2e-16 Identities = 64/161 (39%), Positives = 70/161 (43%), Gaps = 31/161 (19%) Query: 990 GSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSF 1049 G+ LPGS G+ PG R LKG+ G+ G G G G GS Sbjct: 489 GAQTLPGSDSVSTWDGSVRTPGG-------RVKEGGLKGQKGEPGVPGPPGRAGP-PGSP 540 Query: 1050 LMSGPPGLP---GNPGPAGQKGETVVGPQGPPGAPGLPGPPGF----GRPGDPGPPGPPG 1102 + GPPGLP GPAG +TV GPQGP PG PG G G PGDPG G PG Sbjct: 541 CLPGPPGLPCPVSPLGPAGPALQTVPGPQGP---PGPPGRDGTPGRDGEPGDPGEDGKPG 597 Query: 1103 PPGPPAILGA-------------AVALPGPPGPPGQPGLPG 1130 GP G V GPPGP G PG PG Sbjct: 598 DTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPG 638 Score = 35.0 bits (79), Expect = 0.50 Identities = 30/104 (28%), Positives = 40/104 (38%), Gaps = 22/104 (21%) Query: 1031 GDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPGFG 1090 G + + E+ + + G LPG+ + G +V P G GL G Sbjct: 467 GGSSTEDSRSEEVEEQTTVASLGAQTLPGSDSVSTWDG-SVRTPGGRVKEGGLKG----- 520 Query: 1091 RPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNL 1134 + G+PG PGPPG GPP G P LPG L Sbjct: 521 QKGEPGVPGPPGRAGPP----------------GSPCLPGPPGL 548 Score = 32.3 bits (72), Expect = 3.2 Identities = 21/63 (33%), Positives = 25/63 (39%), Gaps = 14/63 (22%) Query: 1053 GPPGLPGNPGPAGQKGETVVGPQGPPGAPG------------LPGPPGFGRPGDP--GPP 1098 GP L G + G T+ +G P +PG P PP GRP P GP Sbjct: 150 GPLALAGPSSTPQENGTTLWPSRGIPSSPGAHTTEAGTLPAPTPSPPSLGRPWAPLTGPS 209 Query: 1099 GPP 1101 PP Sbjct: 210 VPP 212 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 413 bits (1062), Expect = e-115 Identities = 382/1213 (31%), Positives = 494/1213 (40%), Gaps = 236/1213 (19%) Query: 51 LPSSVSFVTGY--------GGFPAYSFGPGANVGRPARTLIPSTFF-RDFAISVVVKPSS 101 LP ++ TG+ G AY A + P + L P++ F DF+I VK + Sbjct: 51 LPDGITKTTGFCATRRSSKGPDVAYRVTKDAQLSAPTKQLYPASAFPEDFSILTTVK--A 108 Query: 102 TRGGVLFAITDAFQKVIYLGLRLSGVEDGHQRIILYYTEPGSHVSQEAAAF-SVPVMTHR 160 +G F ++ ++ G++ G+E G + LY G ++ F + + + Sbjct: 109 KKGSQAFLVSIYNEQ----GIQQIGLELGRSPVFLYEDHTGKPGPEDYPLFRGINLSDGK 164 Query: 161 WNRFAMIVQGEEVTLLVNCEEHSRIPFQRSSQALAFESSAGIFMGNAGATGLERFTGSLQ 220 W+R A+ V + VTL+++C++ + RS + GI + E F G +Q Sbjct: 165 WHRIALSVHKKNVTLILDCKKKTTKFLDRSDHPMI--DINGIIVFGTRILDEEVFEGDIQ 222 Query: 221 QLTVHPDPRTPEELCD---PEESSASGETSGLQ---------EADGVAEILEAVTYTQAS 268 QL D R + C+ P+ +A +T Q E DG E TY Sbjct: 223 QLLFVSDHRAAYDYCEHYSPDCDTAVPDTPQSQDPNPDEYYTEGDG-----EGETYYYEY 277 Query: 269 PKEAKVEPINTPPTPS-SPFEDMELSGEPVPEGTLETTNMSIIQHSSPKQGSGEIL---- 323 P E + PTPS P E + + E E T T + + +S G E + Sbjct: 278 PYYEDPEDLGKEPTPSKKPVEAAKETTEVPEELTPTPTEAAPMPETSEGAGKEEDVGIGD 337 Query: 324 ---------------NDTLEGVHSVDGDPITDSGSGAGAFLDIAEEKNLAATAAGLAEVP 368 +D G + D TD G+GA A+ N + A E Sbjct: 338 YDYVPSEDYYTPSPYDDLTYGEGEENPDQPTDPGAGAEIPTSTADTSNSSNPAPPPGEGA 397 Query: 369 ISTAGEAEASSV-------------PTG-----GPTLSMSTENPEEGVTPGPDNEE-RLA 409 GE ++ PT GP + + + EG+ GP E+ + Sbjct: 398 DDLEGEFTEETIRNLDENYYDPYYDPTSSPSEIGPGMPANQDTIYEGI-GGPRGEKGQKG 456 Query: 410 ATAAGEAEALASMPGEVEASGVAPGELDLSMSAQSLGEEATVGPSSEDSLTTAAAATEVS 469 A E L P E PG +G+ GP L Sbjct: 457 EPAIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGL---------- 506 Query: 470 LSTFEDEEASGVPTDGLAPLTATMAPER------AVTSGP--GDEEDLAAATTEEPLITA 521 A G+P P T M P R A + GP +E A A ++ + Sbjct: 507 ------PGADGLPG---PPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLAL 557 Query: 522 GGEE-----SGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELP- 575 G +G P P GPP G G KGE GD G + P Sbjct: 558 RGPAGPMGLTGRPGPVGPP-----------------------GSGGLKGEPGDVGPQGPR 594 Query: 576 ---GPPEPSGPVGPTAGAEAEGSGLGWGSDVG----SGSGDLVG--SEQLLRGPPGPPGP 626 GPP P+G G A ++G+ G G G L G E+ RG PGP GP Sbjct: 595 GVQGPPGPAGKPGRRGRAGSDGA-RGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGP 653 Query: 627 PGLPGIPGKPGTDVFMGPPGSPGEDGP---AGEPGPPGPEGQPGVDGATGLPGMKGEKGA 683 PG PG G+ G D +GP G PGE GP G GPPGP G PGV G G PG KG G Sbjct: 654 PGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGP 713 Query: 684 RGPNGSVGEKGDPGNRGLP------GPPGKKGQAGPPGVMGPPGPPGPPGPPG----PGC 733 +G G G++G+PG +GLP GPPG+KG G PG+ G PG GPPG PG PG Sbjct: 714 QGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGE 773 Query: 734 TMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDG----------A 783 G G +G + P A G++G KG +G KGE G G Sbjct: 774 KGGQGPPGPQGP-----IGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIKGDR 828 Query: 784 SIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPD---GLPGLPGFPGPR 840 +GPPGPRG G G + P +GPPG G+PGLPG+PG + Sbjct: 829 GEIGPPGPRGEDGP---------EGPKGRGGPNGDPGPLGPPGEKGKLGVPGLPGYPGRQ 879 Query: 841 GPKGDTGLPGFPGLKGEQGEKGEPG-----------AILTEDIPLERLMGKKGEPGMHGA 889 GPKG G PGFPG GE+G +G PG E P + GK G G G Sbjct: 880 GPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPRGERGP-RGITGKPGPKGNSGG 938 Query: 890 PGPMGP---KGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPP 946 GP GP +GP G +G G PG G PG G G G PG +G G G GPPGPP Sbjct: 939 DGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGHPG--QRGETGFQGKTGPPGPP 996 Query: 947 GAV--INIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQ 1004 G V G P+ R HPG P G GE+G GL G +G KGD Sbjct: 997 GVVGPQGPTGETGPMGER---------GHPGPP------GPPGEQGLPGLAGKEGTKGDP 1041 Query: 1005 GAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPA 1064 G G PG G G +GF G++G G + G+ + G G PG PGPA Sbjct: 1042 GPAGLPGK--------------DGPPGLRGFPGDRGLPGPV-GALGLKGNEGPPGPPGPA 1086 Query: 1065 GQKGET----VVGPQGPPGAPGLPGPPG-FGRPGDPGPPGPPGPPGPPAILGAAVALPGP 1119 G GE GP G PG PG GPPG G G PG GP GP G + G V LPGP Sbjct: 1087 GSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQG-PVGLPGP 1145 Query: 1120 PGPPGQPGLPGSR 1132 GP G PG G + Sbjct: 1146 AGPVGPPGEDGDK 1158 Score = 371 bits (952), Expect = e-102 Identities = 256/658 (38%), Positives = 298/658 (45%), Gaps = 95/658 (14%) Query: 496 ERAVTSGPGDEEDLAAATTEEPLITAGGEESGSPP----PDGPPLPLPTVAPERWITPAQ 551 +R T G+ P +GG+ PP P+GP P P+ P Sbjct: 911 QRGPTGPRGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPG 970 Query: 552 REHVGMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLV 611 ++ G+ G G +GE G G+ GPP P G VGP G E +G Sbjct: 971 KD--GLPGHPGQRGETGFQGKT--GPPGPPGVVGPQ-GPTGETGPMG------------- 1012 Query: 612 GSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGA 671 E+ GPPGPPG GLPG+ GK GT GP G PG+DGP G G PG G PG GA Sbjct: 1013 --ERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGA 1070 Query: 672 TGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGP 731 GL G +G G GP GS GE+G G G G PG+ G GPPG G G PG GP GP Sbjct: 1071 LGLKGNEGPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGP 1130 Query: 732 GCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGAS----IVG 787 +G L L P +G GE GD+G GE G G+ G Sbjct: 1131 -------------AGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQG 1177 Query: 788 PPGPRGPPGHIKVLSNSLINITHGFMNFSDI---------PELVGPPGPDGLPGLPGFPG 838 PPGP GP G I S + G + GPPGP GL GLPG PG Sbjct: 1178 PPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPG 1237 Query: 839 PRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGP 898 +G GD G G PG G +G G PGA G +G PG G PG +G KG Sbjct: 1238 EKGETGDVGQMGPPGPPGPRGPSGAPGAD-----------GPQGPPGGIGNPGAVGEKGE 1286 Query: 899 PGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFP 958 PG GE GLPG G PG G +G KG+ GP G GPPGP GPPG KG+ P Sbjct: 1287 PGEAGEPGLPGEGGPPGPKGERGEKGE-----SGPSGAAGPPGPKGPPGDD-GPKGSPGP 1340 Query: 959 IPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAY 1018 + P D PG P G G+KG G PG G G G GP GPP Sbjct: 1341 VG------FPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPP----- 1389 Query: 1019 LRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPP 1078 +G G G +G +GEKG G + GPPG G GP G G+ GP Sbjct: 1390 ------GKRGPPGPAGPEGRQGEKG-AKGEAGLEGPPGKTGPIGPQGAPGKP-----GPD 1437 Query: 1079 GAPGLPGPPGF-GRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNLV 1135 G G+PGP G G PG PGP GPPGP GPP + G L G GP G+ G PG L+ Sbjct: 1438 GLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPG----LKGDSGPKGEKGHPGLIGLI 1491 Score = 307 bits (787), Expect = 4e-83 Identities = 229/577 (39%), Positives = 255/577 (44%), Gaps = 93/577 (16%) Query: 502 GPGDEEDLAAATTEEPLITAGGEESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQA 561 GP E+ L +E G +G P DGPP L +R + P +G+KG Sbjct: 1021 GPPGEQGLPGLAGKEGTKGDPGP-AGLPGKDGPP-GLRGFPGDRGL-PGPVGALGLKGNE 1077 Query: 562 GPKGEKGDAGEE-------------LPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSG 608 GP G G AG +PG P P GP GP A G G G Sbjct: 1078 GPPGPPGPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQ 1137 Query: 609 DLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGV 668 VG L GP GP GPPG G G+ G G G GE GP G GP GP GQPG Sbjct: 1138 GPVG----LPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGP 1193 Query: 669 DGATGLPGMKGE------KGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGP 722 GA G PG +G+ KG GP G G G G +GLPGPPG+KG+ G G MGPPGP Sbjct: 1194 SGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGP 1253 Query: 723 PGPPGPPG-PGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMD 781 PGP GP G PG G G G+ + E GL GE G GPKGERG Sbjct: 1254 PGPRGPSGAPGADGPQG--PPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEK 1311 Query: 782 GAS----IVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGP---------- 827 G S GPPGP+GPPG + G + F P G PGP Sbjct: 1312 GESGPSGAAGPPGPKGPPGDDGPKGSP------GPVGFPGDPGPPGEPGPAGQDGPPGDK 1365 Query: 828 --------DGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIP------ 873 G PG G PGP GP G G PG G +G QGEKG G E P Sbjct: 1366 GDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPI 1425 Query: 874 -LERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGT------KGDP 926 + GK G G+ G PGP+G +G PG G G PG G PGL GLKG KG P Sbjct: 1426 GPQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHP 1485 Query: 927 GVI-MQGPPG---------LPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGS 976 G+I + GPPG LPGP G GP G I G PI PG Sbjct: 1486 GLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQ-GITGPSGPI------------GPPGP 1532 Query: 977 PELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPP 1013 P L G KG KGS G G KGE G G GPPGPP Sbjct: 1533 PGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPP 1569 Score = 303 bits (776), Expect = 8e-82 Identities = 228/606 (37%), Positives = 271/606 (44%), Gaps = 89/606 (14%) Query: 400 PGPDNEERLAATAAGEAE----ALASMPGEVEASGVA--PGELDLSMSAQSLGEEATVGP 453 PGP E+ L A E A +PG+ G+ PG+ L +LG + GP Sbjct: 1020 PGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGP 1079 Query: 454 SSEDSLTTAAAATEVSLSTFEDEEASGVPTDGLAPLTATMAPERAVTSGPGDEEDLAAAT 513 A + E P P+ P GP E+ A Sbjct: 1080 PGPPG--PAGSPGERG------------PAGAAGPIGIPGRPGPQGPPGPAGEK--GAPG 1123 Query: 514 TEEPLITAGGEESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEE 573 + P AG + G P G P P V P P + G G+ G KG KGD GE+ Sbjct: 1124 EKGPQGPAGRD--GLQGPVGLPGPAGPVGP-----PGEDGDKGEIGEPGQKGSKGDKGEQ 1176 Query: 574 LPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGS--EQLLRGPPGPPGPPGLPG 631 GPP P+GP GP G+ G G L G ++ RG PGPPGP GL G Sbjct: 1177 --GPPGPTGPQGPIGQPGPSGAD---GEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQG 1231 Query: 632 IPGKPGT-----DVF-MGPPGSPGEDGPAGEPGPPGPEG--------------------- 664 +PG PG DV MGPPG PG GP+G PG GP+G Sbjct: 1232 LPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAG 1291 Query: 665 QPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPG 724 +PG+ G G PG KGE+G +G +G G G PG +G PG G KG GP G G PGPPG Sbjct: 1292 EPGLPGEGGPPGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPG 1351 Query: 725 PPGPPGPGCTMGLGFEDTE--GSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDG 782 PGP G G +D E +GS EP S P G G G G +GE+G G Sbjct: 1352 EPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKG 1411 Query: 783 -ASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRG 841 A + GPPG GP G G L G PGP G GLPG PGP G Sbjct: 1412 EAGLEGPPGKTGPIG------------PQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDG 1459 Query: 842 PKGDTGLPGFPGLKGE---QGEKGEPGAILTEDIPLER-LMGKKGEPGMHGAPGPMGPKG 897 P G G PG PGLKG+ +GEKG PG I P E+ G +G PG G+ GP G +G Sbjct: 1460 PPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQG 1519 Query: 898 PPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVI-MQGPPGLPGPPGPPGPPGAVINIKGAI 956 G G G PG PG PG G KG KG G +G G PGPPGPPGPPG VI Sbjct: 1520 ITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQ----- 1574 Query: 957 FPIPVR 962 P+P++ Sbjct: 1575 -PLPIQ 1579 Score = 208 bits (530), Expect = 3e-53 Identities = 202/621 (32%), Positives = 236/621 (38%), Gaps = 167/621 (26%) Query: 563 PKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGS-GLGWGSDVGSGSGDLVGSEQLLRGPP 621 P + +A +E PE P A E S G G DVG G D V SE P Sbjct: 292 PSKKPVEAAKETTEVPEELTPTPTEAAPMPETSEGAGKEEDVGIGDYDYVPSEDYYTPSP 351 Query: 622 GPPGPPGL----PGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGM 677 G P P PG + P S + + P PP PG +GA L G Sbjct: 352 YDDLTYGEGEENPDQPTDPGAGAEI--PTSTADTSNSSNPAPP-----PG-EGADDLEGE 403 Query: 678 KGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGL 737 E+ R + + DP P P GP P Sbjct: 404 FTEETIRNLDENYY---DP-------------------YYDPTSSPSEIGPGMPA----- 436 Query: 738 GFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGM--DGASIVGPPGPRGPP 795 ++ T G+ G +G++G KGE + G I GPPGP GP Sbjct: 437 -------------------NQDTIYEGIGGPRGEKGQKGEPAIIEPGMLIEGPPGPEGPA 477 Query: 796 GHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLK 855 G L GPPG G G G PG RGP PG PGL Sbjct: 478 G------------------------LPGPPGTMGPTGQVGDPGERGP------PGRPGLP 507 Query: 856 GEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPM-----------------GPKGP 898 G G G PG +L L + G G G+ GPM +GP Sbjct: 508 GADGLPGPPGTMLM-------LPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGP 560 Query: 899 PGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFP 958 G G G PG G PG GLKG GD G QGP G+ GPPGP G PG +G Sbjct: 561 AGPMGLTGRPGPVGPPGSGGLKGEPGDVGP--QGPRGVQGPPGPAGKPGR----RGRAGS 614 Query: 959 IPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAY 1018 R MP T G +G G GLPG KG +GD G GPPGPP D Sbjct: 615 DGARG---MPGQTGPKGD---------RGFDGLAGLPGEKGHRGDPGPSGPPGPPGD--- 659 Query: 1019 LRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETV----VGP 1074 + +G++G+ G +G GE G G GPPG PG PG G G+ VGP Sbjct: 660 -----DGERGDDGEVGPRGLPGEPGP-RGLLGPKGPPGPPGPPGVTGMDGQPGPKGNVGP 713 Query: 1075 QGPPGAPG---------LPGPPG----------FGRPGDPGPPGPPGPPGPPAILG--AA 1113 QG PG PG LPGP G G+PG PG PG GPPG P G Sbjct: 714 QGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGE 773 Query: 1114 VALPGPPGPPGQPGLPGSRNL 1134 GPPGP G G PG R + Sbjct: 774 KGGQGPPGPQGPIGYPGPRGV 794 Score = 178 bits (452), Expect = 3e-44 Identities = 160/508 (31%), Positives = 196/508 (38%), Gaps = 126/508 (24%) Query: 695 DPGNRGLPGPPGKKGQAGPPGVMGPPG---PPGPPGPPGPGCTMGLGFEDTEGSGSTQLL 751 DP + G P KK P P P P + G G E+ G G + Sbjct: 282 DPEDLGKEPTPSKKPVEAAKETTEVPEELTPTPTEAAPMPETSEGAGKEEDVGIGDYDYV 341 Query: 752 NEPKLSRPTAAIGLKGEKGDRGPK--------GERGMDGASIVGPPGPRGPPGHI----- 798 P+ L +G+ P E A P PPG Sbjct: 342 PSEDYYTPSPYDDLTYGEGEENPDQPTDPGAGAEIPTSTADTSNSSNPAPPPGEGADDLE 401 Query: 799 -KVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGE 857 + ++ N+ + + + P G PG+P DT G G +GE Sbjct: 402 GEFTEETIRNLDENY--YDPYYDPTSSPSEIG-PGMPA-------NQDTIYEGIGGPRGE 451 Query: 858 QGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLN 917 +G+KGEP AI+ + +E G +G G+ G PG MGP G G GE G PGRPG PG + Sbjct: 452 KGQKGEP-AIIEPGMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGAD 510 Query: 918 GLKGTKG-------------DPG--------------VIMQ----------GPPGLPGPP 940 GL G G D G I+Q GP GL G P Sbjct: 511 GLPGPPGTMLMLPFRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRP 570 Query: 941 GPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGE 1000 GP GPPG+ +KG P D G GV+G G G PG +G Sbjct: 571 GPVGPPGSG-GLKGE------------PGDVGPQGP------RGVQGPPGPAGKPGRRGR 611 Query: 1001 KGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKG------EKGEKGDINGSFLMSGP 1054 G GA+G PG G GD+GF G EKG +GD S GP Sbjct: 612 AGSDGARGMPGQT--------------GPKGDRGFDGLAGLPGEKGHRGDPGPS----GP 653 Query: 1055 PGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPGFGRPGDPGPPGPPGPPGPPAILG--- 1111 PG PG+ G G GE GP G PG PGP G GP GPPGPPGPP + G Sbjct: 654 PGPPGDDGERGDDGEV-----GPRGLPGEPGPRGL-----LGPKGPPGPPGPPGVTGMDG 703 Query: 1112 -----AAVALPGPPGPPGQPGLPGSRNL 1134 V G PGPPGQ G PG++ L Sbjct: 704 QPGPKGNVGPQGEPGPPGQQGNPGAQGL 731 >gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo sapiens] Length = 1767 Score = 411 bits (1056), Expect = e-114 Identities = 368/1186 (31%), Positives = 471/1186 (39%), Gaps = 178/1186 (15%) Query: 52 PSSVSFVTGY--------GGFPAYSFGPGANVGRPARTLIPS-TFFRDFAISVVVKPSST 102 P +S TG+ G AY A + P + L P TF DF+I VKP Sbjct: 51 PEGISKTTGFCTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKG 110 Query: 103 RGGVLFAITDAFQKVIYLGLRLSGVEDGHQRIILYYTEPGSHVSQEAAAF-SVPVMTHRW 161 L +I + G++ GVE G + L+ G ++ F +V + +W Sbjct: 111 IQSFLLSIYNEH------GIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKW 164 Query: 162 NRFAMIVQGEEVTLLVNCEEHSRIPFQRSSQALAFESSAGIFMGNAGATGLERFTGSLQQ 221 +R A+ V+ + VT++V+C++ + P RS +A+ + GI + E F G +QQ Sbjct: 165 HRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIV--DTNGITVFGTRILDEEVFEGDIQQ 222 Query: 222 LTVHPDPRTPEELCD--------PEESSASGETSGLQEADGVAEILE-----AVTYTQAS 268 + DP+ + C+ +A + + EA+ V + E +Y + Sbjct: 223 FLITGDPKAAYDYCEHYSPDCDSSAPKAAQAQEPQIDEANIVDDFQEYNYGTMESYQTEA 282 Query: 269 PKEAKVEPINTPPTPSSPFEDMELSGEPVPEGTLETTNMSIIQHSSPKQGSGEILNDTLE 328 P+ V N P F + L+GE + S ++ S + L + E Sbjct: 283 PRH--VSGTNEPNPVEEIFTEEYLTGE---------------DYDSQRKNSEDTLYENKE 325 Query: 329 GVHSVDGDPITDSGSGAGAFLDIAEEKNLAATAAGLAEVPISTAGEAEASSVPTGGPTLS 388 + D D + D G F + E + + P S E VP Sbjct: 326 -IDGRDSDLLVDGDLGEYDFYEYKEYE----------DKPTSPPNEEFGPGVPAETDI-- 372 Query: 389 MSTENPEEGVTPGPDNEERLAATAAGEAEALASMPGEVEASGVAPGELDLSMSAQSLGEE 448 TE G + ++ + PG +G+ G L G+ Sbjct: 373 --TETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGIM-GPPGLQGPTGPPGDP 429 Query: 449 ATVGPSSEDSLTTAAA-----ATEVSLSTFEDEEASGVPTDGL--APLTATMAPERAVTS 501 GP L A T + L + S PT A A + R Sbjct: 430 GDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAILQQARIALR 489 Query: 502 GPGDEEDLAA--ATTEEPLITAGGEESGSPPPDGPP----LPLPTVAPERWITPAQREHV 555 GP L P + ESG P P GP P PT P + P Sbjct: 490 GPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGR 549 Query: 556 GMKGQAGPKGEKG-DAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSE 614 GM G+ G KG++G D LPG G GP G G D G L G Sbjct: 550 GMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEA 609 Query: 615 QLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGL 674 GP G GP G PG PG+PG GPPG G GP GEPGPPG +G PG G G Sbjct: 610 ----GPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGP 665 Query: 675 PGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCT 734 G G G +GP G G G PG G PG PGK+GQ+G G +GPPGP GP G PGP Sbjct: 666 QGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGV 725 Query: 735 MGL-GFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRG 793 G G +GS + E +GLKG++G+ G G RG DG GP G G Sbjct: 726 KGADGVRGLKGSKGEK--GEDGFPGFKGDMGLKGDRGEVGQIGPRGEDGPE--GPKGRAG 781 Query: 794 PPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPG 853 P G + G G G+PGLPG+PG +GPKG TG PGFPG Sbjct: 782 PTGDPGPSGQA------------------GEKGKLGVPGLPGYPGRQGPKGSTGFPGFPG 823 Query: 854 LKGEQGEK---GEPGAILTEDIPLER----------LMGKKGEPGMHGAPGP-------- 892 GE+G + G+PG R G KG G G PGP Sbjct: 824 ANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQG 883 Query: 893 -------MGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPG----VIMQGPPGLPGP-- 939 GPKGPPG G+ GLPG PG+ G G +G G PG V QGP G GP Sbjct: 884 PQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIG 943 Query: 940 ----PGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLP 995 PGPPGPPG + GA + + G L F G +G G+ G P Sbjct: 944 ERGHPGPPGPPGEQ-GLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP 1002 Query: 996 GSKGEKGDQGAQGPPGPPLDLAYL----------RHFLNNLKGENGDKGFKGEKGEKGDI 1045 G KG +G QG GP G P + R G G+KG GEKG +G Sbjct: 1003 GLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPA 1062 Query: 1046 NGSFLMSGPPGLPGNPGPAGQKGET----------------VVGPQGPPGAPGLPGPPGF 1089 G + GP GLPG GPAG GE G GPPG PGL GP Sbjct: 1063 -GRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGP--V 1119 Query: 1090 GRPGDPGPPGPPGPPGPPAILG-----AAVALPGPPGPPGQPGLPG 1130 G PG G G PGP G + G A PGPPGP G GLPG Sbjct: 1120 GAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPG 1165 Score = 353 bits (907), Expect = 5e-97 Identities = 252/643 (39%), Positives = 293/643 (45%), Gaps = 107/643 (16%) Query: 517 PLITAGGEESGSPP----PDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGE 572 P T+GG+ PP P GP P+ P+ P ++ G+ G G +GE G G+ Sbjct: 863 PKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD--GLPGHPGQRGETGFQGK 920 Query: 573 ELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGI 632 GPP P G VGP G E +G E+ GPPGPPG GLPG Sbjct: 921 T--GPPGPGGVVGPQ-GPTGETGPIG---------------ERGHPGPPGPPGEQGLPGA 962 Query: 633 PGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGE 692 GK G GP G G+DGPAG G PG G PG GA GL G +G +G GP GS GE Sbjct: 963 AGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGE 1022 Query: 693 KGDPGNRG---LPGPPGKKGQAGPPGVMGPPGPPGPPGP------------PGPGCTMGL 737 +G G G LPG PG +G GP G G PG GP GP PGP G Sbjct: 1023 RGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS 1082 Query: 738 GFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGA----SIVGPPGPRG 793 ED G + EP G KG+KG+ GP G G+ G I G G G Sbjct: 1083 PGED----GDKGEIGEPGQK------GSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPG 1132 Query: 794 PPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPG 853 P G + GF GPPGP GL GLPG PG +G GD G G PG Sbjct: 1133 PRGQQGMFGQKGDEGARGFP---------GPPGPIGLQGLPGPPGEKGENGDVGPMGPPG 1183 Query: 854 LKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGR 913 G +G +G GA G +G PG G+ G +G KG PG E G PG PG Sbjct: 1184 PPGPRGPQGPNGAD-----------GPQGPPGSVGSVGGVGEKGEPG---EAGNPGPPGE 1229 Query: 914 PGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAH 973 G+ G KG +G+ G GPPG GPPG GPPG KG P+ P D Sbjct: 1230 AGVGGPKGERGEKGEA--GPPGAAGPPGAKGPPGDD-GPKGNPGPVG------FPGDPGP 1280 Query: 974 PGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDK 1033 PG P GV G+KG G PG G G G GPPGPP G G + Sbjct: 1281 PGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPP--------GKRGPPGAAGAE 1332 Query: 1034 GFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPG-FGRP 1092 G +GEKG KG+ +G G PG GP G +G G GP G G+PGP G G P Sbjct: 1333 GRQGEKGAKGE-------AGAEGPPGKTGPVGPQGP--AGKPGPEGLRGIPGPVGEQGLP 1383 Query: 1093 GDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNLV 1135 G G GPPGP GPP + G L G PG G+ G PG L+ Sbjct: 1384 GAAGQDGPPGPMGPPGLPG----LKGDPGSKGEKGHPGLIGLI 1422 Score = 337 bits (864), Expect = 5e-92 Identities = 245/635 (38%), Positives = 288/635 (45%), Gaps = 125/635 (19%) Query: 515 EEPLITAGGEES--GSPPPDG-----PPLPLPTVAPERWITPAQREHVGMKGQAGPKG-- 565 E+ L A G+E G P P G P L ER + AQ G+KG GP+G Sbjct: 956 EQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP-GLKGGEGPQGPP 1014 Query: 566 -------EKGDAGEE----LPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSE 614 E+G AG LPG P P GP GP A G G G Sbjct: 1015 GPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG-------- 1066 Query: 615 QLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGL 674 ++GP G PGP G G PG+ G +G PG G G GE GPPGP G G GA G+ Sbjct: 1067 --VQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGI 1124 Query: 675 PGMKGEKGARGPNGSVGEKGDPGNRG------------LPGPPGKKGQAGPPGVMGPPGP 722 G GE G RG G G+KGD G RG LPGPPG+KG+ G G MGPPGP Sbjct: 1125 AGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGP 1184 Query: 723 PGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDG 782 PGP GP GP G + +G + ++G GEKG+ G G G G Sbjct: 1185 PGPRGPQGPN-----GADGPQGPPGS-----------VGSVGGVGEKGEPGEAGNPGPPG 1228 Query: 783 -ASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRG 841 A + GP G RG G GPPG G PG G PG G Sbjct: 1229 EAGVGGPKGERGEKGE------------------------AGPPGAAGPPGAKGPPGDDG 1264 Query: 842 PKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGH 901 PKG+ G GFPG + G GEPG + + ++ G+ G+PG G PGP G GPPG Sbjct: 1265 PKGNPGPVGFPG---DPGPPGEPGPAGQDGVGGDK--GEDGDPGQPGPPGPSGEAGPPGP 1319 Query: 902 KGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPG--AVINIKGAIFPI 959 G+ G PG G G G KG KG+ G +GPPG GP GP GP G ++G P+ Sbjct: 1320 PGKRGPPGAAGAEGRQGEKGAKGEAGA--EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV 1377 Query: 960 PVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYL 1019 + +P G P + G+ G KG PGSKGEKG G G GPP + Sbjct: 1378 GEQG---LPGAAGQDGPPGPMGPPGLPGLKGD---PGSKGEKGHPGLIGLIGPPGE---- 1427 Query: 1020 RHFLNNLKGENGDKGFKGEKGE---KGDIN-----GSFLMSGPPGLPGNPGPAGQKGETV 1071 +GE GD+G G +G KGD G GPPGLPG GP G KG T Sbjct: 1428 -------QGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST- 1479 Query: 1072 VGPQGPPGAPGLPGPPGFGRPGDPGPPGPPGPPGP 1106 GP G G GLPGPPG PGPPG P P Sbjct: 1480 -GPAGQKGDSGLPGPPG-----SPGPPGEVIQPLP 1508 Score = 286 bits (731), Expect = 1e-76 Identities = 223/610 (36%), Positives = 259/610 (42%), Gaps = 99/610 (16%) Query: 400 PGPDNEERLAATAAGEA-------EALASMPGEVEASGVAPGELDLSMSAQSLGEEATVG 452 PGP E+ L A E + ++ G G PGE L + + G + G Sbjct: 951 PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGF-PGERGLPGAQGAPGLKGGEG 1009 Query: 453 PSSEDSLTTAAAATEVSLSTFEDEEASGVPTDGLAPLTATMAPERAVTSGPGDEEDLAAA 512 P + E T G L P+ PG + A Sbjct: 1010 PQGPPGPVGSPG------------ERGSAGTAGPIGLPGRPGPQ----GPPGPAGEKGAP 1053 Query: 513 TTEEPLITAGGEESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGE 572 + P AG + G P G P P +P + G G+ G KG KGD GE Sbjct: 1054 GEKGPQGPAGRD--GVQGPVGLPGPAGPAG-----SPGEDGDKGEIGEPGQKGSKGDKGE 1106 Query: 573 E-LPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGS--EQLLRGPPGPPGPPGL 629 PGPP GPVG A G G G G + G ++ RG PGPPGP GL Sbjct: 1107 NGPPGPPGLQGPVG------APGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGL 1160 Query: 630 PGIPGKPGT-----DVF-MGPPGSPGEDGPAGEPGPPGPEGQPGVDGATG---------- 673 G+PG PG DV MGPPG PG GP G G GP+G PG G+ G Sbjct: 1161 QGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGE 1220 Query: 674 --LPGMKGEKGARGPNGSVGEKGD---------PGNRGLPGPPGKKGQAGPPGVMGPPGP 722 PG GE G GP G GEKG+ PG +G PG G KG GP G G PGP Sbjct: 1221 AGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGP 1280 Query: 723 PGPPGPPGPGCTMGLGFEDTE--------GSGSTQLLNEPKLSRPTAAIGLKGEKGDRGP 774 PG PGP G G ED + SG P P A G +G +G++G Sbjct: 1281 PGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGA 1340 Query: 775 KGERGMDG-ASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGL 833 KGE G +G GP GP+GP G G IP GP G GLPG Sbjct: 1341 KGEAGAEGPPGKTGPVGPQGPAG------------KPGPEGLRGIP---GPVGEQGLPGA 1385 Query: 834 PGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLER-LMGKKGEPGMHGAPGP 892 G GP GP G GLPG G G +GEKG PG I P E+ G +G PG G+PG Sbjct: 1386 AGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGA 1445 Query: 893 MGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQ-GPPGLPGPPGPPGPPGAVIN 951 G G PG G G PG PG PG G KG KG G Q G GLPGPPG PGPPG VI Sbjct: 1446 KGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQ 1505 Query: 952 IKGAIFPIPV 961 P+P+ Sbjct: 1506 ------PLPI 1509 Score = 208 bits (529), Expect = 3e-53 Identities = 140/369 (37%), Positives = 162/369 (43%), Gaps = 69/369 (18%) Query: 555 VGMKGQAGPKGEKGDAGEE----LPGPPEPSGPVGPTA--------------------GA 590 +G++G GP GEKG+ G+ PGPP P GP GP G Sbjct: 1158 IGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGE 1217 Query: 591 EAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPG------KPGTDVFMGP 644 E G + G G E+ GPPG GPPG G PG PG F G Sbjct: 1218 PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGD 1277 Query: 645 PGSPGEDGPAGE------------PGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGE 692 PG PGE GPAG+ PG PGP G G G G PG +G GA G G GE Sbjct: 1278 PGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGE 1337 Query: 693 KGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLN 752 KG G G GPPGK G GP G G PGP G G PGP GL G+ Sbjct: 1338 KGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGL-------PGAAGQDG 1390 Query: 753 EPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGF 812 P P GLKG+ G +G KG G+ G ++GPPG +G G + T G Sbjct: 1391 PPGPMGPPGLPGLKGDPGSKGEKGHPGLIG--LIGPPGEQGEKGDRGLPG------TQGS 1442 Query: 813 MNFSDIPELVGPPGPDGLPGLPGFPGPRGPKG------------DTGLPGFPGLKGEQGE 860 + GP GP G PG PG PGP+GPKG D+GLPG PG G GE Sbjct: 1443 PGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGE 1502 Query: 861 KGEPGAILT 869 +P IL+ Sbjct: 1503 VIQPLPILS 1511 Score = 204 bits (520), Expect = 4e-52 Identities = 153/418 (36%), Positives = 180/418 (43%), Gaps = 123/418 (29%) Query: 767 GEKGDRGPKGERGM--DGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGP 824 G G++G KGE + G + GPPGP GP G ++GP Sbjct: 381 GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAG------------------------IMGP 416 Query: 825 PGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEP 884 PG G G PG PG RGP PG PGL G G G PG +L P Sbjct: 417 PGLQGPTGPPGDPGDRGP------PGRPGLPGADGLPGPPGTMLML-------------P 457 Query: 885 GMHGAPGPMGP--------------------KGPPGHKGEFGLPGRPGRPGLNGLKGTKG 924 +G G GP +GPPG G G PG G PG +G KG G Sbjct: 458 FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 517 Query: 925 DPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHG 984 DPG QGP G+ GPPGP G PG R PG P G Sbjct: 518 DPGP--QGPRGVQGPPGPTGKPGK-------------RGRPGADGGRGMPGEP------G 556 Query: 985 VKGEKGSWGLPG---SKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGE 1041 KG++G GLPG KG +G++G QGPPGPP D + ++GE+G+ G +G GE Sbjct: 557 AKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGD--------DGMRGEDGEIGPRGLPGE 608 Query: 1042 KGDINGSFLMSGPPGLPGNPGPAGQKG----ETVVGPQGPPGAPG---------LPGPPG 1088 G G G PG PG PG AG G + +GPQG PG PG LPGP G Sbjct: 609 AGP-RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 667 Query: 1089 -FGRPGDPGPPGPPG---------PPGPPAILGAA--VALPGPPGPPGQPGLPGSRNL 1134 G PG+ GP G PG PPG P G + GPPGP G G PG R + Sbjct: 668 PIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGV 725 Score = 155 bits (393), Expect = 2e-37 Identities = 133/397 (33%), Positives = 162/397 (40%), Gaps = 49/397 (12%) Query: 363 GLAEVPISTAGEAEASSVPTGGPTLSMSTENPE-EGVTPGPDNEERLAATAAGEAEALAS 421 GL +P + E V GP P+ GP + G E Sbjct: 1159 GLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK--G 1216 Query: 422 MPGEVEASGVAPGELDLSMSAQSLGEEATVGPSSEDSLTTAAAATEVSLSTFEDEEASGV 481 PGE G PGE + GE+ GP AA + D+ G Sbjct: 1217 EPGEAGNPG-PPGEAGVGGPKGERGEKGEAGPPG-------AAGPPGAKGPPGDDGPKGN 1268 Query: 482 PTDGLAPLTATMAPERAVTSGPGDEEDLAAATTEEPLITAGGE--ESGSPPPDGPPLPLP 539 P P+ P GP ++ + GG+ E G P GPP P Sbjct: 1269 P----GPVGFPGDPGPPGEPGPAGQDGV------------GGDKGEDGDPGQPGPPGPSG 1312 Query: 540 TVAPERWITPAQREH---VGMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEG-S 595 P P +R G +G+ G KG KG+AG E GPP +GPVGP A G Sbjct: 1313 EAGPPG--PPGKRGPPGAAGAEGRQGEKGAKGEAGAE--GPPGKTGPVGPQGPAGKPGPE 1368 Query: 596 GL-GWGSDVGS-GSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPG------S 647 GL G VG G G + GPPGP GPPGLPG+ G PG+ G PG Sbjct: 1369 GLRGIPGPVGEQGLPGAAGQD----GPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGP 1424 Query: 648 PGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGK 707 PGE G G+ G PG +G PG G G+PG G G GP G G +G GN+G GP G+ Sbjct: 1425 PGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQ 1484 Query: 708 KGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEG 744 KG +G PG G PGPPG P P + TEG Sbjct: 1485 KGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEG 1521 Score = 35.8 bits (81), Expect = 0.29 Identities = 21/66 (31%), Positives = 27/66 (40%), Gaps = 5/66 (7%) Query: 1074 PQGPPG---APGLPGPPGFGRPG--DPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGL 1128 P PP PG+P G G G G PA++ + + GPPGP G G+ Sbjct: 354 PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGI 413 Query: 1129 PGSRNL 1134 G L Sbjct: 414 MGPPGL 419 >gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo sapiens] Length = 1736 Score = 408 bits (1049), Expect = e-113 Identities = 377/1191 (31%), Positives = 474/1191 (39%), Gaps = 171/1191 (14%) Query: 9 QCWCLLMLLSVSTPLPAVTQTRGATETASQGHLDLTQLIGVP-LPSSVSFVTGY-GGFPA 66 +C LL+LL + L A GA +D+ + + P LP V G A Sbjct: 6 RCHRLLLLLPLVLGLSAAPGWAGAPP------VDVLRALRFPSLPDGVRRAKGICPADVA 59 Query: 67 YSFGPGANVGRPARTLIPSTFFRDFAISVVVKPSSTRGGVLFAITDAFQKVIYLGLRLSG 126 Y A + P R L P F +DF++ VV+ TR G+ + + G+R G Sbjct: 60 YRVARPAQLSAPTRQLFPGGFPKDFSLLTVVR---TRPGLQAPLLTLYSAQ---GVRQLG 113 Query: 127 VEDGHQRIILYYTEPGSHVSQEAAAF-SVPVMTHRWNRFAMIVQGEEVTLLVNCEEHSRI 185 +E G LY + G F + + +W+R A+ V+G+ VTL+V+C++ Sbjct: 114 LELGRPVRFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTR 173 Query: 186 PFQRSSQALAFESSAGIFMGNAGATGLERFTGSLQQLTVHPDPRTPEELCDPEESSASGE 245 P RS++ + + G+ + A E F G +Q+L + P + E C+ +E G Sbjct: 174 PLPRSARPVL--DTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEG- 230 Query: 246 TSGLQEADGVAEILEAVTYTQASPKEAKVEPINTPPTPSSPFEDMELSGEPVPEGTLETT 305 G +E + A Q P P N P S P E + EP + T Sbjct: 231 --GQRERPQNQQPHRAQRSPQQQPSRLH-RPQNQEPQ-SQPTESLYYDYEPPYYDVMTTG 286 Query: 306 NMSIIQHSSPKQGSGEILNDTL-----EGVHSVDGDPITDS------GSGA--------- 345 Q +P + EIL +L E + P D G G Sbjct: 287 TTPDYQDPTPGEEE-EILESSLLPPLEEEQTDLQVPPTADRFQAEEYGEGGTDPPEGPYD 345 Query: 346 ---GAFLDIAEEKNLA-------ATAAGLAEVPISTAGEAEASSVPTGGPTLSMSTENPE 395 G D EE L A + A P GE +V G M E P Sbjct: 346 YTYGYGDDYREETELGPALSAETAHSGAAAHGPRGLKGEKGEPAVLEPG----MLVEGP- 400 Query: 396 EGVTPGPDNEERLAATAAGEAEALASMPGEVEASGVAPGELDLSMSAQSLGEEATVGPSS 455 PGP+ L + PG V PGE A G + GP Sbjct: 401 ----PGPEGPAGLIGPPG-----IQGNPGPVGD----PGERGPPGRAGLPGSDGAPGPPG 447 Query: 456 EDSLTT----AAAATEVSLSTFEDEEASGVPTDGLAPLTATMAPERAVTSGPGDEEDLAA 511 + + + + ++ +A + L P T PG Sbjct: 448 TSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGPPGP-MGYTGRPG------- 499 Query: 512 ATTEEPLITAGGE----ESGSPPPDGPPLPLPTVAPERWITPAQREHV-GMKGQAGPKGE 566 PL G ESG P GP P P R G +G G G Sbjct: 500 -----PLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGV 554 Query: 567 KGDAG-EELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLL--RGPPGP 623 KGD G + LPG P G G T G G D G +G L GP G Sbjct: 555 KGDRGFDGLPGLPGEKGHRGDTGAQGLPGPP---GEDGERGDDGEIGPRGLPGESGPRGL 611 Query: 624 PGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGA 683 GP G PGIPG PG GP G G GP GEPGPPG +G PG G G G G G Sbjct: 612 LGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGE 671 Query: 684 RGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGL-GFEDT 742 +GP G G G PG+ G PG PGK+G G G GP GP GP G PGP G+ G Sbjct: 672 KGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGL 731 Query: 743 EGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLS 802 +G + E IG+KG++G+ G G RG DG GP G GP G Sbjct: 732 KGHKGEK--GEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPE--GPKGRTGPTGD----- 782 Query: 803 NSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKG 862 P L+G G G+PGLPG+PG +GPKG G PGFPG GE+G +G Sbjct: 783 -------------PGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARG 829 Query: 863 EPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGT 922 L GK G G G GP G +GP G G+ G G G G +G G Sbjct: 830 --------------LSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGE 875 Query: 923 KGDPGVIMQGPPGLPGPPGPPGPPG-----------AVINIKGAIFPIPVRPHCKMPVDT 971 +G PG QGP G PGP GPPGPPG + +G P P P P Sbjct: 876 RGLPG--PQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGP-PGPPGVVGPQGA 932 Query: 972 AHPGSPELITFH-GVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGEN 1030 A P H G G G GLPG+ G++G +G GPPG P G Sbjct: 933 AGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAP-----------GKDGPA 981 Query: 1031 GDKGFKGEKGEKGDINGSFLM-----SGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPG 1085 G +GF GE+G G G L SGPPG G+PG G G GP GPPG PG G Sbjct: 982 GLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSG--GPIGPPGRPGPQG 1039 Query: 1086 PPG-FGRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNLV 1135 PPG G G PG GP GP G + G V LPGP GPPG G G + V Sbjct: 1040 PPGAAGEKGVPGEKGPIGPTGRDGVQG-PVGLPGPAGPPGVAGEDGDKGEV 1089 Score = 360 bits (923), Expect = 7e-99 Identities = 258/644 (40%), Positives = 298/644 (46%), Gaps = 99/644 (15%) Query: 556 GMKGQAGPKGEKGDAGEE-LPGPPEP---SGPVGPTAGAEAEGSGLGWGSDVGSGSGDLV 611 G+ G++GP+G G G +PGPP GP GP +G G G+ L Sbjct: 601 GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLP 660 Query: 612 GSEQLL-----RGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGP---PGPE 663 G + + +GP G PG PG+PG G PG GPPG+ G GP+G GP PGP Sbjct: 661 GPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPR 720 Query: 664 GQPGVDGATGLPGMKGEKGARGP---NGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPP 720 G GVDG GL G KGEKG G G +G KGD G G+PG G+ G GP G GP Sbjct: 721 GVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPGSRGEDGPEGPKGRTGPT 780 Query: 721 GPPGPPGPPGPGCTMGL----GFEDTEG-SGSTQLLNEPKLSRPTAAIGL------KGEK 769 G PGPPG G +G+ G+ +G GS P S A GL +GE+ Sbjct: 781 GDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARGLSGKSGPRGER 840 Query: 770 GDRGPKGERGMDGAS-------IVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELV 822 G GP+G+RG GA+ G GP GPPG + G + P Sbjct: 841 GPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGL---------PGPQGPNGFPGPK 891 Query: 823 GPPGPDGLPGLPGFPGPRGP---KGDTGLPGFPGLKGEQGEKGEPGAILTEDIP------ 873 GPPGP G GLPG PG RG +G TG PG PG+ G QG GE G + P Sbjct: 892 GPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPP 951 Query: 874 ----LERLMGK---KGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDP 926 L GK KG+PG GAPG GP G G GE GLPG G PGL G +G G P Sbjct: 952 GEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPP 1011 Query: 927 GVIMQ-------------GPPGLPGPPGPPGPPG--AVINIKGAIFPIPVRPHCKMPVDT 971 G GPPG PGP GPPG G V KG I P R + PV Sbjct: 1012 GPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTG-RDGVQGPVGL 1070 Query: 972 AHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENG 1031 P P + G G+KG G PG KG KG++G GPPGPP + G G Sbjct: 1071 PGPAGPPGVA--GEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPI-----------GPVG 1117 Query: 1032 DKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPGF-G 1090 G G GE G GP G G G G +G GP GP G GLPGP G G Sbjct: 1118 QPGAAGADGEPG-------ARGPQGHFGAKGDEGTRGFN--GPPGPIGLQGLPGPSGEKG 1168 Query: 1091 RPGDPGPPGPPGPPGP--PAILGAAVALPGPPGPPGQPGLPGSR 1132 GD GP GPPGPPGP PA A GPPG G G PG + Sbjct: 1169 ETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEK 1212 Score = 352 bits (902), Expect = 2e-96 Identities = 265/678 (39%), Positives = 302/678 (44%), Gaps = 94/678 (13%) Query: 496 ERAVTSGPGDEEDLAAATTEEPLITAGGEESGSPPPD----GPPLPLPTVAPERWITPAQ 551 ER T G A T+GG+ PP + GP P P+ P Sbjct: 839 ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPG 898 Query: 552 REHVGMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLV 611 ++ G+ G G +GE G G+ GPP P G VGP GA E +G Sbjct: 899 KD--GLPGHPGQRGEVGFQGKT--GPPGPPGVVGPQ-GAAGETGPMG------------- 940 Query: 612 GSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGA 671 E+ GPPGPPG GLPG GK GT GPPG+PG+DGPAG G PG G PG G Sbjct: 941 --ERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGG 998 Query: 672 TGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGP--- 728 GL G +G G GP GS GE+G G+ G GPPG+ G GPPG G G PG GP Sbjct: 999 PGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP 1058 Query: 729 ------------PGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKG 776 PGP G+ ED G + +P G KG KG+ GP G Sbjct: 1059 TGRDGVQGPVGLPGPAGPPGVAGED----GDKGEVGDP------GQKGTKGNKGEHGPPG 1108 Query: 777 ERGMDG-------ASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDG 829 G G A G PG RGP GH + T GF GPPGP G Sbjct: 1109 PPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGD---EGTRGFN---------GPPGPIG 1156 Query: 830 LPGLPGFPGPRGPKGDTGLPGFP---------GLKGEQGEKGEPGAILTEDIPLER-LMG 879 L GLPG G +G GD G G P G G G +G PG + P E+ G Sbjct: 1157 LQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG 1216 Query: 880 KKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGP 939 + G PG+ G PG GP+G G KGE G PG PG PG G G G G GP G PG Sbjct: 1217 ESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKG--NPGPVGFPGD 1274 Query: 940 PGPPGP--PGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGS 997 PGPPG P KG P T G P + G G GS G G Sbjct: 1275 PGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGG 1334 Query: 998 KGEKGDQGAQGPPGP--PLDLA--YLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSG 1053 KG KGD GA G PG P+ A + + L+G G G +G G G G G Sbjct: 1335 KGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQA-GPPGPVG 1393 Query: 1054 PPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPG-FGRPGDPGPPGPPGPPGPPAILGA 1112 PPGLPG G AG KGE +G PG GL GPPG G GD G PGP G PG +G Sbjct: 1394 PPGLPGLRGDAGAKGE-----KGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGI 1448 Query: 1113 AVALPGPPGPPGQPGLPG 1130 A GP GP G PGLPG Sbjct: 1449 PGA-SGPIGPGGPPGLPG 1465 Score = 344 bits (883), Expect = 3e-94 Identities = 263/696 (37%), Positives = 309/696 (44%), Gaps = 141/696 (20%) Query: 502 GPGDEEDLAAATTEEPLITAGGEESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQA 561 GP E+ L +E G G+P DGP L ER + P G+KG Sbjct: 949 GPPGEQGLPGTAGKEGTKGDPGPP-GAPGKDGPA-GLRGFPGERGL-PGTAGGPGLKGNE 1005 Query: 562 GPKG---------EKGDAGEELP-GPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLV 611 GP G E+G AG P GPP GP GP GA E G +G D V Sbjct: 1006 GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPP-GAAGEKGVPGEKGPIGPTGRDGV 1064 Query: 612 GSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGA 671 +GP G PGP G PG+ G+ G +G PG G G GE GPPGP G G G Sbjct: 1065 ------QGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQ 1118 Query: 672 TGLPGMKGEKGARGPNGSVGEKGDPGNRG------------LPGPPGKKGQAGPPGVMGP 719 G G GE GARGP G G KGD G RG LPGP G+KG+ G G MGP Sbjct: 1119 PGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGP 1178 Query: 720 PGPPGPPGPPGPGCTMGLGFEDTEGS-GSTQLLNEP-KLSRP--TAAIGLKGEKGDRGPK 775 PGPPGP GP GP G + +G G L P + P + + G++GE G +GP+ Sbjct: 1179 PGPPGPRGPAGPN-----GADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPR 1233 Query: 776 GERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPG 835 GERG G S G PG GPPG P GP G G G Sbjct: 1234 GERGEKGES--GQPGEPGPPG---------------------------PKGPTGDDGPKG 1264 Query: 836 FPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGP 895 PGP G GD G PG G +G+ G KG+ G+ GEPG G+PGP G Sbjct: 1265 NPGPVGFPGDPGPPGEGGPRGQDGAKGD--------------RGEDGEPGQPGSPGPTGE 1310 Query: 896 KGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGP-----PGAVI 950 GPPG G+ G G PG G G KG KGDPG I G PG GP GP GP P + Sbjct: 1311 NGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAI--GAPGKTGPVGPAGPAGKPGPDGLR 1368 Query: 951 NIKGAIFPIPVRP----HCKMPVDTAHPGSPELITFHGVKGEKGSWGL------PGSKGE 1000 + G++ RP P PG P L G KGEKG GL PG +GE Sbjct: 1369 GLPGSVGQ-QGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGE 1427 Query: 1001 KGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGN 1060 KGD+G GP G P G+ G+ G G G G GPPGLPG Sbjct: 1428 KGDRGLPGPQGSP--------------GQKGEMGIPGASGPIGP-------GGPPGLPGP 1466 Query: 1061 PGPAGQKGETVVGPQGPPGAPGLPGPPGFGRPGDPGPPGPPGPPGP--------PAILGA 1112 GP G KG T GP GP G G+ GPPG PGPPG P P ++ G+ Sbjct: 1467 AGPKGAKGAT--GPGGPKGEKGVQGPPGH-----PGPPGEVIQPLPIQMPKKTRRSVDGS 1519 Query: 1113 AVALPGPPGPP-GQPGLPGSRNLVTAFSNMDDMLQK 1147 + P G PG PG L F ++D + ++ Sbjct: 1520 RLMQEDEAIPTGGAPGSPG--GLEEIFGSLDSLREE 1553 >gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo sapiens] Length = 1629 Score = 407 bits (1046), Expect = e-113 Identities = 387/1201 (32%), Positives = 490/1201 (40%), Gaps = 178/1201 (14%) Query: 9 QCWCLLMLLSVSTPLPAVTQTRGATETASQGHLDLTQLIGVP-LPSSVSFVTGY-GGFPA 66 +C LL+LL + L A GA +D+ + + P LP V G A Sbjct: 6 RCHRLLLLLPLVLGLSAAPGWAGAPP------VDVLRALRFPSLPDGVRRAKGICPADVA 59 Query: 67 YSFGPGANVGRPARTLIPSTFFRDFAISVVVKPSSTRGGVLFAITDAFQKVIYLGLRLSG 126 Y A + P R L P F +DF++ VV+ TR G+ + + G+R G Sbjct: 60 YRVARPAQLSAPTRQLFPGGFPKDFSLLTVVR---TRPGLQAPLLTLYSAQ---GVRQLG 113 Query: 127 VEDGHQRIILYYTEPGSHVSQEAAAF-SVPVMTHRWNRFAMIVQGEEVTLLVNCEEHSRI 185 +E G LY + G F + + +W+R A+ V+G+ VTL+V+C++ Sbjct: 114 LELGRPVRFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTR 173 Query: 186 PFQRSSQALAFESSAGIFMGNAGATGLERFTGSLQQLTVHPDPRTPEELCDPEESSASGE 245 P RS++ + + G+ + A E F G +Q+L + P + E C+ +E G Sbjct: 174 PLPRSARPVL--DTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEG- 230 Query: 246 TSGLQEADGVAEILEAVTYTQASPKEAKVEPINTPPTPSSPFEDMELSGEPVPEGTLETT 305 G +E + A Q P P N P + L GE LE Sbjct: 231 --GQRERPQNQQPHRAQRSPQQQPSRLH-RPQNQEPQSQAAHGPRGLKGEKGEPAVLEP- 286 Query: 306 NMSIIQHSSPKQGSGEILNDTLEGVHSVDGDPITDSGSGAGAFLDIAEEKNLAATAAGLA 365 M + P+ +G I ++G GDP G AGL Sbjct: 287 GMLVEGPPGPEGPAGLIGPPGIQGNPGPVGDPGERGPPGR----------------AGLP 330 Query: 366 EVPISTAGEAEASSVPTGGPTLSMSTENPEEGVTPGP---DNEERLAATAAGEAEALASM 422 G A P G +L + G GP E + A AL Sbjct: 331 -------GSDGAPGPP--GTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQARLALRGP 381 Query: 423 PGEVEASGVAPGELDLSMSAQSLGEEATVGPSSEDSLT--TAAAATEVSLSTFEDEEASG 480 PG + +G PG L S GE +GP T + A G Sbjct: 382 PGPMGYTG-RPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARG 440 Query: 481 VPTDGLAPLTATMAPERAVTSGPG--DEEDLAAATTEEPLITAGGEESGSPPPDGPPLPL 538 +P D + +R PG E+ T + L GE+ G DG Sbjct: 441 MPGD------PGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED-GERGDDGE---- 489 Query: 539 PTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEE-LPGPPEP---SGPVGPTAGAEAEG 594 + P G+ G++GP+G G G +PGPP GP GP +G Sbjct: 490 --IGPR-----------GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQG 536 Query: 595 SGLGWGSDVGSGSGDLVGSEQLL-----RGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPG 649 G G+ L G + + +GP G PG PG+PG G PG GPPG+ G Sbjct: 537 EPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKG 596 Query: 650 EDGPAGEPGP---PGPEGQPGVDGATGLPGMKGEKGARGP---NGSVGEKGDPGNRGLPG 703 GP+G GP PGP G GVDG GL G KGEKG G G +G KGD G G+PG Sbjct: 597 NQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRGEVGVPG 656 Query: 704 PPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGL----GFEDTEG-SGSTQLLNEPKLSR 758 G+ G GP G GP G PGPPG G +G+ G+ +G GS P S Sbjct: 657 SRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASG 716 Query: 759 PTAAIGL------KGEKGDRGPKGERGMDGAS-------IVGPPGPRGPPGHIKVLSNSL 805 A GL +GE+G GP+G+RG GA+ G GP GPPG + Sbjct: 717 EKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGL----- 771 Query: 806 INITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGP---KGDTGLPGFPGLKGEQGEKG 862 G + P GPPGP G GLPG PG RG +G TG PG PG+ G QG G Sbjct: 772 ----PGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAG 827 Query: 863 EPGAILTEDIP----------LERLMGK---KGEPGMHGAPGPMGPKGPPGHKGEFGLPG 909 E G + P L GK KG+PG GAPG GP G G GE GLPG Sbjct: 828 ETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPG 887 Query: 910 RPGRPGLNGLKGTKGDPGVIMQ-------------GPPGLPGPPGPPGPPG--AVINIKG 954 G PGL G +G G PG GPPG PGP GPPG G V KG Sbjct: 888 TAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKG 947 Query: 955 AIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPL 1014 I P R + PV P P + G G+KG G PG KG KG++G GPPGPP Sbjct: 948 PIGPTG-RDGVQGPVGLPGPAGPPGVA--GEDGDKGEVGDPGQKGTKGNKGEHGPPGPPG 1004 Query: 1015 DLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGP 1074 + G G G G GE G GP G G G G +G GP Sbjct: 1005 PI-----------GPVGQPGAAGADGEPG-------ARGPQGHFGAKGDEGTRGFN--GP 1044 Query: 1075 QGPPGAPGLPGPPGF-GRPGDPGPPGPPGPPGP--PAILGAAVALPGPPGPPGQPGLPGS 1131 GP G GLPGP G G GD GP GPPGPPGP PA A GPPG G G PG Sbjct: 1045 PGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGE 1104 Query: 1132 R 1132 + Sbjct: 1105 K 1105 Score = 362 bits (929), Expect = 1e-99 Identities = 250/634 (39%), Positives = 285/634 (44%), Gaps = 79/634 (12%) Query: 525 ESGSPPPDGPPLPLPTVAPERWITPAQREHV-GMKGQAGPKGEKGDAG-EELPGPPEPSG 582 ESG P GP P P R G +G G G KGD G + LPG P G Sbjct: 405 ESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKG 464 Query: 583 PVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLL--RGPPGPPGPPGLPGIPGKPGTDV 640 G T G G D G +G L GP G GP G PGIPG PG Sbjct: 465 HRGDTGAQGLPGPP---GEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRG 521 Query: 641 FMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRG 700 GP G G GP GEPGPPG +G PG G G G G G +GP G G G PG+ G Sbjct: 522 MDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG 581 Query: 701 LPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGL-GFEDTEGSGSTQLLNEPKLSRP 759 PG PGK+G G G GP GP GP G PGP G+ G +G + E Sbjct: 582 PPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEK--GEDGFPGF 639 Query: 760 TAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIP 819 IG+KG++G+ G G RG DG GP G GP G P Sbjct: 640 KGDIGVKGDRGEVGVPGSRGEDGPE--GPKGRTGPTGD------------------PGPP 679 Query: 820 ELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMG 879 L+G G G+PGLPG+PG +GPKG G PGFPG GE+G +G L G Sbjct: 680 GLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARG--------------LSG 725 Query: 880 KKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGP 939 K G G G GP G +GP G G+ G G G G +G G +G PG QGP G PGP Sbjct: 726 KSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPG--PQGPNGFPGP 783 Query: 940 PGPPGPPG-----------AVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFH-GVKG 987 GPPGPPG + +G P P P P A P H G G Sbjct: 784 KGPPGPPGKDGLPGHPGQRGEVGFQGKTGP-PGPPGVVGPQGAAGETGPMGERGHPGPPG 842 Query: 988 EKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDING 1047 G GLPG+ G++G +G GPPG P G G +GF GE+G G G Sbjct: 843 PPGEQGLPGTAGKEGTKGDPGPPGAP-----------GKDGPAGLRGFPGERGLPGTAGG 891 Query: 1048 SFLM-----SGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPG-FGRPGDPGPPGPP 1101 L SGPPG G+PG G G GP GPPG PG GPPG G G PG GP Sbjct: 892 PGLKGNEGPSGPPGPAGSPGERGAAGSG--GPIGPPGRPGPQGPPGAAGEKGVPGEKGPI 949 Query: 1102 GPPGPPAILGAAVALPGPPGPPGQPGLPGSRNLV 1135 GP G + G V LPGP GPPG G G + V Sbjct: 950 GPTGRDGVQG-PVGLPGPAGPPGVAGEDGDKGEV 982 Score = 352 bits (902), Expect = 2e-96 Identities = 265/678 (39%), Positives = 302/678 (44%), Gaps = 94/678 (13%) Query: 496 ERAVTSGPGDEEDLAAATTEEPLITAGGEESGSPPPD----GPPLPLPTVAPERWITPAQ 551 ER T G A T+GG+ PP + GP P P+ P Sbjct: 732 ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPG 791 Query: 552 REHVGMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLV 611 ++ G+ G G +GE G G+ GPP P G VGP GA E +G Sbjct: 792 KD--GLPGHPGQRGEVGFQGKT--GPPGPPGVVGPQ-GAAGETGPMG------------- 833 Query: 612 GSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGA 671 E+ GPPGPPG GLPG GK GT GPPG+PG+DGPAG G PG G PG G Sbjct: 834 --ERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGG 891 Query: 672 TGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGP--- 728 GL G +G G GP GS GE+G G+ G GPPG+ G GPPG G G PG GP Sbjct: 892 PGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP 951 Query: 729 ------------PGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKG 776 PGP G+ ED G + +P G KG KG+ GP G Sbjct: 952 TGRDGVQGPVGLPGPAGPPGVAGED----GDKGEVGDP------GQKGTKGNKGEHGPPG 1001 Query: 777 ERGMDG-------ASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDG 829 G G A G PG RGP GH + T GF GPPGP G Sbjct: 1002 PPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGD---EGTRGFN---------GPPGPIG 1049 Query: 830 LPGLPGFPGPRGPKGDTGLPGFP---------GLKGEQGEKGEPGAILTEDIPLER-LMG 879 L GLPG G +G GD G G P G G G +G PG + P E+ G Sbjct: 1050 LQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG 1109 Query: 880 KKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGP 939 + G PG+ G PG GP+G G KGE G PG PG PG G G G G GP G PG Sbjct: 1110 ESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKG--NPGPVGFPGD 1167 Query: 940 PGPPGP--PGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGS 997 PGPPG P KG P T G P + G G GS G G Sbjct: 1168 PGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGG 1227 Query: 998 KGEKGDQGAQGPPGP--PLDLA--YLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSG 1053 KG KGD GA G PG P+ A + + L+G G G +G G G G G Sbjct: 1228 KGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQA-GPPGPVG 1286 Query: 1054 PPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPG-FGRPGDPGPPGPPGPPGPPAILGA 1112 PPGLPG G AG KGE +G PG GL GPPG G GD G PGP G PG +G Sbjct: 1287 PPGLPGLRGDAGAKGE-----KGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGI 1341 Query: 1113 AVALPGPPGPPGQPGLPG 1130 A GP GP G PGLPG Sbjct: 1342 PGA-SGPIGPGGPPGLPG 1358 Score = 344 bits (883), Expect = 3e-94 Identities = 263/696 (37%), Positives = 309/696 (44%), Gaps = 141/696 (20%) Query: 502 GPGDEEDLAAATTEEPLITAGGEESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQA 561 GP E+ L +E G G+P DGP L ER + P G+KG Sbjct: 842 GPPGEQGLPGTAGKEGTKGDPGPP-GAPGKDGPA-GLRGFPGERGL-PGTAGGPGLKGNE 898 Query: 562 GPKG---------EKGDAGEELP-GPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLV 611 GP G E+G AG P GPP GP GP GA E G +G D V Sbjct: 899 GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPP-GAAGEKGVPGEKGPIGPTGRDGV 957 Query: 612 GSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGA 671 +GP G PGP G PG+ G+ G +G PG G G GE GPPGP G G G Sbjct: 958 ------QGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQ 1011 Query: 672 TGLPGMKGEKGARGPNGSVGEKGDPGNRG------------LPGPPGKKGQAGPPGVMGP 719 G G GE GARGP G G KGD G RG LPGP G+KG+ G G MGP Sbjct: 1012 PGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGP 1071 Query: 720 PGPPGPPGPPGPGCTMGLGFEDTEGS-GSTQLLNEP-KLSRP--TAAIGLKGEKGDRGPK 775 PGPPGP GP GP G + +G G L P + P + + G++GE G +GP+ Sbjct: 1072 PGPPGPRGPAGPN-----GADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPR 1126 Query: 776 GERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPG 835 GERG G S G PG GPPG P GP G G G Sbjct: 1127 GERGEKGES--GQPGEPGPPG---------------------------PKGPTGDDGPKG 1157 Query: 836 FPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGP 895 PGP G GD G PG G +G+ G KG+ G+ GEPG G+PGP G Sbjct: 1158 NPGPVGFPGDPGPPGEGGPRGQDGAKGD--------------RGEDGEPGQPGSPGPTGE 1203 Query: 896 KGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGP-----PGAVI 950 GPPG G+ G G PG G G KG KGDPG I G PG GP GP GP P + Sbjct: 1204 NGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAI--GAPGKTGPVGPAGPAGKPGPDGLR 1261 Query: 951 NIKGAIFPIPVRP----HCKMPVDTAHPGSPELITFHGVKGEKGSWGL------PGSKGE 1000 + G++ RP P PG P L G KGEKG GL PG +GE Sbjct: 1262 GLPGSVGQ-QGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGE 1320 Query: 1001 KGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGN 1060 KGD+G GP G P G+ G+ G G G G GPPGLPG Sbjct: 1321 KGDRGLPGPQGSP--------------GQKGEMGIPGASGPIGP-------GGPPGLPGP 1359 Query: 1061 PGPAGQKGETVVGPQGPPGAPGLPGPPGFGRPGDPGPPGPPGPPGP--------PAILGA 1112 GP G KG T GP GP G G+ GPPG PGPPG P P ++ G+ Sbjct: 1360 AGPKGAKGAT--GPGGPKGEKGVQGPPGH-----PGPPGEVIQPLPIQMPKKTRRSVDGS 1412 Query: 1113 AVALPGPPGPP-GQPGLPGSRNLVTAFSNMDDMLQK 1147 + P G PG PG L F ++D + ++ Sbjct: 1413 RLMQEDEAIPTGGAPGSPG--GLEEIFGSLDSLREE 1446 Score = 121 bits (304), Expect = 4e-27 Identities = 101/310 (32%), Positives = 125/310 (40%), Gaps = 89/310 (28%) Query: 901 HKGEFGLPGRPGRPGLNGLKGTKG-----DPGVIMQGPP--------------------- 934 H+ + P G GLKG KG +PG++++GPP Sbjct: 256 HRPQNQEPQSQAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGNPGPV 315 Query: 935 ------------GLPGPPGPPGPPGAVINIK-------GAIFPIPVRPHCK-----MPVD 970 GLPG G PGPPG + + G P+ + Sbjct: 316 GDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQAR 375 Query: 971 TAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGP-----PLDLAYLRHFLNN 1025 A G P + + G G G G PG KGE GD G QGP GP P A R Sbjct: 376 LALRGPPGPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRR----G 431 Query: 1026 LKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPG 1085 G +G +G G+ G KGD G GLPG PG G +G+T G QG PG PG G Sbjct: 432 RAGADGARGMPGDPGVKGD-------RGFDGLPGLPGEKGHRGDT--GAQGLPGPPGEDG 482 Query: 1086 PPG-------FGRPGDP------GPPGPPGPPGPPAILG--------AAVALPGPPGPPG 1124 G G PG+ GP GPPG PGPP + G ++ G PGPPG Sbjct: 483 ERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPPG 542 Query: 1125 QPGLPGSRNL 1134 Q G PG++ L Sbjct: 543 QQGTPGTQGL 552 >gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo sapiens] Length = 1650 Score = 406 bits (1044), Expect = e-113 Identities = 389/1207 (32%), Positives = 495/1207 (41%), Gaps = 169/1207 (14%) Query: 9 QCWCLLMLLSVSTPLPAVTQTRGATETASQGHLDLTQLIGVP-LPSSVSFVTGY-GGFPA 66 +C LL+LL + L A GA +D+ + + P LP V G A Sbjct: 6 RCHRLLLLLPLVLGLSAAPGWAGAPP------VDVLRALRFPSLPDGVRRAKGICPADVA 59 Query: 67 YSFGPGANVGRPARTLIPSTFFRDFAISVVVKPSSTRGGVLFAITDAFQKVIYLGLRLSG 126 Y A + P R L P F +DF++ VV+ TR G+ + + G+R G Sbjct: 60 YRVARPAQLSAPTRQLFPGGFPKDFSLLTVVR---TRPGLQAPLLTLYSAQ---GVRQLG 113 Query: 127 VEDGHQRIILYYTEPGSHVSQEAAAF-SVPVMTHRWNRFAMIVQGEEVTLLVNCEEHSRI 185 +E G LY + G F + + +W+R A+ V+G+ VTL+V+C++ Sbjct: 114 LELGRPVRFLYEDQTGRPQPPSQPVFRGLSLADGKWHRVAVAVKGQSVTLIVDCKKRVTR 173 Query: 186 PFQRSSQALAFESSAGIFMGNAGATGLERFTGSLQQLTVHPDPRTPEELCDPEESSASGE 245 P RS++ + + G+ + A E F G +Q+L + P + E C+ +E G Sbjct: 174 PLPRSARPVL--DTHGVIIFGARILDEEVFEGDVQELAIVPGVQAAYESCEQKELECEG- 230 Query: 246 TSGLQEADGVAEILEAVTYTQASP----KEAKVEPINTPPTPSSPFEDMELSGEPVPEGT 301 G +E + A Q P + EP + PTP E +E S P E Sbjct: 231 --GQRERPQNQQPHRAQRSPQQQPSRLHRPQNQEPQSQDPTPGEEEEILESSLLPPLEEA 288 Query: 302 LETTNMSIIQHSSPKQGSGEILNDT-LEGVHSVDGDPITDSGSGAGAFLDIAEEKNLAAT 360 P+ GE LE V+G P + +G I + N Sbjct: 289 AH----------GPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGI--QGNPGPV 336 Query: 361 AAGLAEVPISTAGEAEASSVP-TGGPTLSMSTENPEEGVTPGP---DNEERLAATAAGEA 416 P AG + P G +L + G GP E + A Sbjct: 337 GDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFGSGGGDKGPVVAAQEAQAQAILQQAR 396 Query: 417 EALASMPGEVEASGVAPGELDLSMSAQSLGEEATVGPSSEDSLT--TAAAATEVSLSTFE 474 AL PG + +G PG L S GE +GP T Sbjct: 397 LALRGPPGPMGYTG-RPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAG 455 Query: 475 DEEASGVPTDGLAPLTATMAPERAVTSGPG--DEEDLAAATTEEPLITAGGEESGSPPPD 532 + A G+P D + +R PG E+ T + L GE+ G D Sbjct: 456 ADGARGMPGD------PGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGED-GERGDD 508 Query: 533 GPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEE-LPGPPEP---SGPVGPTA 588 G + P G+ G++GP+G G G +PGPP GP GP Sbjct: 509 GE------IGPR-----------GLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKG 551 Query: 589 GAEAEGSGLGWGSDVGSGSGDLVGSEQLL-----RGPPGPPGPPGLPGIPGKPGTDVFMG 643 +G G G+ L G + + +GP G PG PG+PG G PG G Sbjct: 552 SLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEG 611 Query: 644 PPGSPGEDGPAGEPGP---PGPEGQPGVDGATGLPGMKGEKGARGP---NGSVGEKGDPG 697 PPG+ G GP+G GP PGP G GVDG GL G KGEKG G G +G KGD G Sbjct: 612 PPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEKGEDGFPGFKGDIGVKGDRG 671 Query: 698 NRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGL----GFEDTEG-SGSTQLLN 752 G+PG G+ G GP G GP G PGPPG G +G+ G+ +G GS Sbjct: 672 EVGVPGSRGEDGPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPG 731 Query: 753 EPKLSRPTAAIGL------KGEKGDRGPKGERGMDGAS-------IVGPPGPRGPPGHIK 799 P S A GL +GE+G GP+G+RG GA+ G GP GPPG Sbjct: 732 FPGASGEKGARGLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG 791 Query: 800 VLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGP---KGDTGLPGFPGLKG 856 + G + P GPPGP G GLPG PG RG +G TG PG PG+ G Sbjct: 792 L---------PGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVG 842 Query: 857 EQGEKGEPGAILTEDIP----------LERLMGK---KGEPGMHGAPGPMGPKGPPGHKG 903 QG GE G + P L GK KG+PG GAPG GP G G G Sbjct: 843 PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPG 902 Query: 904 EFGLPGRPGRPGLNGLKGTKGDPGVIMQ-------------GPPGLPGPPGPPGPPG--A 948 E GLPG G PGL G +G G PG GPPG PGP GPPG G Sbjct: 903 ERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKG 962 Query: 949 VINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQG 1008 V KG I P R + PV P P + G G+KG G PG KG KG++G G Sbjct: 963 VPGEKGPIGPTG-RDGVQGPVGLPGPAGPPGVA--GEDGDKGEVGDPGQKGTKGNKGEHG 1019 Query: 1009 PPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKG 1068 PPGPP + G G G G GE G GP G G G G +G Sbjct: 1020 PPGPPGPI-----------GPVGQPGAAGADGEPG-------ARGPQGHFGAKGDEGTRG 1061 Query: 1069 ETVVGPQGPPGAPGLPGPPGF-GRPGDPGPPGPPGPPGP--PAILGAAVALPGPPGPPGQ 1125 GP GP G GLPGP G G GD GP GPPGPPGP PA A GPPG G Sbjct: 1062 FN--GPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGN 1119 Query: 1126 PGLPGSR 1132 G PG + Sbjct: 1120 LGPPGEK 1126 Score = 362 bits (929), Expect = 1e-99 Identities = 250/634 (39%), Positives = 285/634 (44%), Gaps = 79/634 (12%) Query: 525 ESGSPPPDGPPLPLPTVAPERWITPAQREHV-GMKGQAGPKGEKGDAG-EELPGPPEPSG 582 ESG P GP P P R G +G G G KGD G + LPG P G Sbjct: 426 ESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKG 485 Query: 583 PVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLL--RGPPGPPGPPGLPGIPGKPGTDV 640 G T G G D G +G L GP G GP G PGIPG PG Sbjct: 486 HRGDTGAQGLPGPP---GEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRG 542 Query: 641 FMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRG 700 GP G G GP GEPGPPG +G PG G G G G G +GP G G G PG+ G Sbjct: 543 MDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDG 602 Query: 701 LPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGL-GFEDTEGSGSTQLLNEPKLSRP 759 PG PGK+G G G GP GP GP G PGP G+ G +G + E Sbjct: 603 PPGHPGKEGPPGTKGNQGPSGPQGPLGYPGPRGVKGVDGIRGLKGHKGEK--GEDGFPGF 660 Query: 760 TAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIP 819 IG+KG++G+ G G RG DG GP G GP G P Sbjct: 661 KGDIGVKGDRGEVGVPGSRGEDGPE--GPKGRTGPTGD------------------PGPP 700 Query: 820 ELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMG 879 L+G G G+PGLPG+PG +GPKG G PGFPG GE+G +G L G Sbjct: 701 GLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGARG--------------LSG 746 Query: 880 KKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGP 939 K G G G GP G +GP G G+ G G G G +G G +G PG QGP G PGP Sbjct: 747 KSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPG--PQGPNGFPGP 804 Query: 940 PGPPGPPG-----------AVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFH-GVKG 987 GPPGPPG + +G P P P P A P H G G Sbjct: 805 KGPPGPPGKDGLPGHPGQRGEVGFQGKTGP-PGPPGVVGPQGAAGETGPMGERGHPGPPG 863 Query: 988 EKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDING 1047 G GLPG+ G++G +G GPPG P G G +GF GE+G G G Sbjct: 864 PPGEQGLPGTAGKEGTKGDPGPPGAP-----------GKDGPAGLRGFPGERGLPGTAGG 912 Query: 1048 SFLM-----SGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPG-FGRPGDPGPPGPP 1101 L SGPPG G+PG G G GP GPPG PG GPPG G G PG GP Sbjct: 913 PGLKGNEGPSGPPGPAGSPGERGAAGSG--GPIGPPGRPGPQGPPGAAGEKGVPGEKGPI 970 Query: 1102 GPPGPPAILGAAVALPGPPGPPGQPGLPGSRNLV 1135 GP G + G V LPGP GPPG G G + V Sbjct: 971 GPTGRDGVQG-PVGLPGPAGPPGVAGEDGDKGEV 1003 Score = 352 bits (902), Expect = 2e-96 Identities = 265/678 (39%), Positives = 302/678 (44%), Gaps = 94/678 (13%) Query: 496 ERAVTSGPGDEEDLAAATTEEPLITAGGEESGSPPPD----GPPLPLPTVAPERWITPAQ 551 ER T G A T+GG+ PP + GP P P+ P Sbjct: 753 ERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGPPG 812 Query: 552 REHVGMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLV 611 ++ G+ G G +GE G G+ GPP P G VGP GA E +G Sbjct: 813 KD--GLPGHPGQRGEVGFQGKT--GPPGPPGVVGPQ-GAAGETGPMG------------- 854 Query: 612 GSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGA 671 E+ GPPGPPG GLPG GK GT GPPG+PG+DGPAG G PG G PG G Sbjct: 855 --ERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGG 912 Query: 672 TGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGP--- 728 GL G +G G GP GS GE+G G+ G GPPG+ G GPPG G G PG GP Sbjct: 913 PGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP 972 Query: 729 ------------PGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKG 776 PGP G+ ED G + +P G KG KG+ GP G Sbjct: 973 TGRDGVQGPVGLPGPAGPPGVAGED----GDKGEVGDP------GQKGTKGNKGEHGPPG 1022 Query: 777 ERGMDG-------ASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDG 829 G G A G PG RGP GH + T GF GPPGP G Sbjct: 1023 PPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGD---EGTRGFN---------GPPGPIG 1070 Query: 830 LPGLPGFPGPRGPKGDTGLPGFP---------GLKGEQGEKGEPGAILTEDIPLER-LMG 879 L GLPG G +G GD G G P G G G +G PG + P E+ G Sbjct: 1071 LQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGPPGGVGNLGPPGEKGEPG 1130 Query: 880 KKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGP 939 + G PG+ G PG GP+G G KGE G PG PG PG G G G G GP G PG Sbjct: 1131 ESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKG--NPGPVGFPGD 1188 Query: 940 PGPPGP--PGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGS 997 PGPPG P KG P T G P + G G GS G G Sbjct: 1189 PGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGG 1248 Query: 998 KGEKGDQGAQGPPGP--PLDLA--YLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSG 1053 KG KGD GA G PG P+ A + + L+G G G +G G G G G Sbjct: 1249 KGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSVGQQGRPGATGQA-GPPGPVG 1307 Query: 1054 PPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPG-FGRPGDPGPPGPPGPPGPPAILGA 1112 PPGLPG G AG KGE +G PG GL GPPG G GD G PGP G PG +G Sbjct: 1308 PPGLPGLRGDAGAKGE-----KGHPGLIGLIGPPGEQGEKGDRGLPGPQGSPGQKGEMGI 1362 Query: 1113 AVALPGPPGPPGQPGLPG 1130 A GP GP G PGLPG Sbjct: 1363 PGA-SGPIGPGGPPGLPG 1379 Score = 344 bits (883), Expect = 3e-94 Identities = 263/696 (37%), Positives = 309/696 (44%), Gaps = 141/696 (20%) Query: 502 GPGDEEDLAAATTEEPLITAGGEESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQA 561 GP E+ L +E G G+P DGP L ER + P G+KG Sbjct: 863 GPPGEQGLPGTAGKEGTKGDPGPP-GAPGKDGPA-GLRGFPGERGL-PGTAGGPGLKGNE 919 Query: 562 GPKG---------EKGDAGEELP-GPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLV 611 GP G E+G AG P GPP GP GP GA E G +G D V Sbjct: 920 GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPP-GAAGEKGVPGEKGPIGPTGRDGV 978 Query: 612 GSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGA 671 +GP G PGP G PG+ G+ G +G PG G G GE GPPGP G G G Sbjct: 979 ------QGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKGNKGEHGPPGPPGPIGPVGQ 1032 Query: 672 TGLPGMKGEKGARGPNGSVGEKGDPGNRG------------LPGPPGKKGQAGPPGVMGP 719 G G GE GARGP G G KGD G RG LPGP G+KG+ G G MGP Sbjct: 1033 PGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGP 1092 Query: 720 PGPPGPPGPPGPGCTMGLGFEDTEGS-GSTQLLNEP-KLSRP--TAAIGLKGEKGDRGPK 775 PGPPGP GP GP G + +G G L P + P + + G++GE G +GP+ Sbjct: 1093 PGPPGPRGPAGPN-----GADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPR 1147 Query: 776 GERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPG 835 GERG G S G PG GPPG P GP G G G Sbjct: 1148 GERGEKGES--GQPGEPGPPG---------------------------PKGPTGDDGPKG 1178 Query: 836 FPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGP 895 PGP G GD G PG G +G+ G KG+ G+ GEPG G+PGP G Sbjct: 1179 NPGPVGFPGDPGPPGEGGPRGQDGAKGD--------------RGEDGEPGQPGSPGPTGE 1224 Query: 896 KGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGP-----PGAVI 950 GPPG G+ G G PG G G KG KGDPG I G PG GP GP GP P + Sbjct: 1225 NGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAI--GAPGKTGPVGPAGPAGKPGPDGLR 1282 Query: 951 NIKGAIFPIPVRP----HCKMPVDTAHPGSPELITFHGVKGEKGSWGL------PGSKGE 1000 + G++ RP P PG P L G KGEKG GL PG +GE Sbjct: 1283 GLPGSVGQ-QGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGE 1341 Query: 1001 KGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGN 1060 KGD+G GP G P G+ G+ G G G G GPPGLPG Sbjct: 1342 KGDRGLPGPQGSP--------------GQKGEMGIPGASGPIGP-------GGPPGLPGP 1380 Query: 1061 PGPAGQKGETVVGPQGPPGAPGLPGPPGFGRPGDPGPPGPPGPPGP--------PAILGA 1112 GP G KG T GP GP G G+ GPPG PGPPG P P ++ G+ Sbjct: 1381 AGPKGAKGAT--GPGGPKGEKGVQGPPGH-----PGPPGEVIQPLPIQMPKKTRRSVDGS 1433 Query: 1113 AVALPGPPGPP-GQPGLPGSRNLVTAFSNMDDMLQK 1147 + P G PG PG L F ++D + ++ Sbjct: 1434 RLMQEDEAIPTGGAPGSPG--GLEEIFGSLDSLREE 1467 Score = 52.4 bits (124), Expect = 3e-06 Identities = 31/68 (45%), Positives = 33/68 (48%), Gaps = 6/68 (8%) Query: 1069 ETVVGPQGPPGAPGLPG--PPGFGRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQP 1126 E GP+G G G P PG G PGP GP G GPP I G PGP G PG+ Sbjct: 287 EAAHGPRGLKGEKGEPAVLEPGMLVEGPPGPEGPAGLIGPPGIQGN----PGPVGDPGER 342 Query: 1127 GLPGSRNL 1134 G PG L Sbjct: 343 GPPGRAGL 350 >gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo sapiens] Length = 1806 Score = 406 bits (1043), Expect = e-113 Identities = 374/1209 (30%), Positives = 478/1209 (39%), Gaps = 185/1209 (15%) Query: 52 PSSVSFVTGY--------GGFPAYSFGPGANVGRPARTLIPS-TFFRDFAISVVVKPSST 102 P +S TG+ G AY A + P + L P TF DF+I VKP Sbjct: 51 PEGISKTTGFCTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKG 110 Query: 103 RGGVLFAITDAFQKVIYLGLRLSGVEDGHQRIILYYTEPGSHVSQEAAAF-SVPVMTHRW 161 L +I + G++ GVE G + L+ G ++ F +V + +W Sbjct: 111 IQSFLLSIYNEH------GIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKW 164 Query: 162 NRFAMIVQGEEVTLLVNCEEHSRIPFQRSSQALAFESSAGIFMGNAGATGLERFTGSLQQ 221 +R A+ V+ + VT++V+C++ + P RS +A+ + GI + E F G +QQ Sbjct: 165 HRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIV--DTNGITVFGTRILDEEVFEGDIQQ 222 Query: 222 LTVHPDPRTPEELCD---PEESSASGETSGLQEAD----------------GVAEILEAV 262 + DP+ + C+ P+ S++ + + QE G AE EA Sbjct: 223 FLITGDPKAAYDYCEHYSPDCDSSAPKAAQAQEPQIDEYAPEDIIEYDYEYGEAEYKEAE 282 Query: 263 TYTQASPKEAKVEPINTPPTPSSPFED-----MELSGEPVPE---GTLETTNMSII---- 310 + T+ P + T F++ ME P GT E + I Sbjct: 283 SVTEG-PTVTEETIAQTEANIVDDFQEYNYGTMESYQTEAPRHVSGTNEPNPVEEIFTEE 341 Query: 311 -----QHSSPKQGSGEILNDTLEGVHSVDGDPITDSGSGAGAFLDIAEEKNLAATAAGLA 365 + S ++ S + L + E + D D + D G F + E + Sbjct: 342 YLTGEDYDSQRKNSEDTLYENKE-IDGRDSDLLVDGDLGEYDFYEYKEYE---------- 390 Query: 366 EVPISTAGEAEASSVPTGGPTLSMSTENPEEGVTPGPDNEERLAATAAGEAEALASMPGE 425 + P S E VP TE G + ++ + PG Sbjct: 391 DKPTSPPNEEFGPGVPAETDI----TETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGP 446 Query: 426 VEASGVAPGELDLSMSAQSLGEEATVGPSSEDSLTTAAA-----ATEVSLSTFEDEEASG 480 +G+ G L G+ GP L A T + L + S Sbjct: 447 AGPAGIM-GPPGLQGPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSK 505 Query: 481 VPTDGL--APLTATMAPERAVTSGPGDEEDLAA--ATTEEPLITAGGEESGSPPPDGPP- 535 PT A A + R GP L P + ESG P P GP Sbjct: 506 GPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESGDPGPQGPRG 565 Query: 536 ---LPLPTVAPERWITPAQREHVGMKGQAGPKGEKG-DAGEELPGPPEPSGPVGPTAGAE 591 P PT P + P GM G+ G KG++G D LPG G GP Sbjct: 566 VQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPG 625 Query: 592 AEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGED 651 G G D G L G GP G GP G PG PG+PG GPPG G Sbjct: 626 PPGDDGMRGEDGEIGPRGLPGEA----GPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNM 681 Query: 652 GPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQA 711 GP GEPGPPG +G PG G G G G G +GP G G G PG G PG PGK+GQ+ Sbjct: 682 GPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQS 741 Query: 712 GPPGVMGPPGPPGPPGPPGPGCTMGL-GFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKG 770 G G +GPPGP GP G PGP G G +GS + E +GLKG++G Sbjct: 742 GEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEK--GEDGFPGFKGDMGLKGDRG 799 Query: 771 DRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGL 830 + G G RG DG GP G GP G + G G G+ Sbjct: 800 EVGQIGPRGEDGPE--GPKGRAGPTGDPGPSGQA------------------GEKGKLGV 839 Query: 831 PGLPGFPGPRGPKGDTGLPGFPGLKGEQGEK---GEPGAILTEDIPLER----------L 877 PGLPG+PG +GPKG TG PGFPG GE+G + G+PG R Sbjct: 840 PGLPGYPGRQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGK 899 Query: 878 MGKKGEPGMHGAPGP---------------MGPKGPPGHKGEFGLPGRPGRPGLNGLKGT 922 G KG G G PGP GPKGPPG G+ GLPG PG+ G G +G Sbjct: 900 PGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGK 959 Query: 923 KGDPG----VIMQGPPGLPGP------PGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTA 972 G PG V QGP G GP PGPPGPPG + GA + + Sbjct: 960 TGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQ-GLPGAAGKEGAKGDPGPQGISG 1018 Query: 973 HPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYL----------RHF 1022 G L F G +G G+ G PG KG +G QG GP G P + R Sbjct: 1019 KDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPG 1078 Query: 1023 LNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGET------------ 1070 G G+KG GEKG +G G + GP GLPG GPAG GE Sbjct: 1079 PQGPPGPAGEKGAPGEKGPQGPA-GRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQK 1137 Query: 1071 ----VVGPQGPPGAPGLPGPPGFGRPGDPGPPGPPGPPGPPAILG-----AAVALPGPPG 1121 G GPPG PGL GP G PG G G PGP G + G A PGPPG Sbjct: 1138 GSKGDKGENGPPGPPGLQGP--VGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPG 1195 Query: 1122 PPGQPGLPG 1130 P G GLPG Sbjct: 1196 PIGLQGLPG 1204 Score = 355 bits (910), Expect = 2e-97 Identities = 271/709 (38%), Positives = 312/709 (44%), Gaps = 128/709 (18%) Query: 525 ESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEE----LPGPPEP 580 E G P GPP + I P G+ G+AGP+G G G PG Sbjct: 617 ERGPQGPPGPPGDDGMRGEDGEIGPR-----GLPGEAGPRGLLGPRGTPGAPGQPGMAGV 671 Query: 581 SGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDV 640 GP GP +G G G L G + + GPPG GP G PG+ G PG D Sbjct: 672 DGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPI-GPPGEKGPQGKPGLAGLPGAD- 729 Query: 641 FMGPPGSPGEDGPAGE------PGPPGPEGQPG---VDGATGLPGMKGEKGARGPNGSVG 691 GPPG PG++G +GE PGP GP G PG V GA G+ G+KG KG +G +G G Sbjct: 730 --GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG 787 Query: 692 EKGDPG------------NRGLPGPPGKKGQAGPPGVMGP------------PGPPGPPG 727 KGD G RG GP G KG+AGP G GP PG PG PG Sbjct: 788 FKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPG 847 Query: 728 PPGPGCTMGL-GFEDTEGS-GSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGAS- 784 GP + G GF G G+ + +P G +G +G RGP G+ G G S Sbjct: 848 RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG 907 Query: 785 ---IVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRG 841 GPPG RGP G G + F GPPG DGLPG PG G G Sbjct: 908 GDGPPGPPGERGPQG------------PQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETG 955 Query: 842 PKGDTGLPGFPGLKGEQGEKGEPGAILTEDIP----------LERLMGK---KGEPGMHG 888 +G TG PG G+ G QG GE G I P L GK KG+PG G Sbjct: 956 FQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQG 1015 Query: 889 APGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVI----------MQGPPGLPG 938 G GP G G GE GLPG G PGL G +G +G PG + GP GLPG Sbjct: 1016 ISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPG 1075 Query: 939 PPGPPGPPG-----AVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWG 993 PGP GPPG KG P R + PV P P G G+KG G Sbjct: 1076 RPGPQGPPGPAGEKGAPGEKGPQGPAG-RDGVQGPVGLPGPAGPA--GSPGEDGDKGEIG 1132 Query: 994 LPGSKGEKGDQGAQGPPGPP-LDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMS 1052 PG KG KGD+G GPPGPP L + GE G +G +G G+KGD G+ Sbjct: 1133 EPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGD-EGARGFP 1191 Query: 1053 GPP---GLPGNPGPAGQKGET-VVGPQGPPGAPGLPGPP-------------------GF 1089 GPP GL G PGP G+KGE VGP GPPG PG GP G Sbjct: 1192 GPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGV 1251 Query: 1090 GRPGDPGPPGPPGPPGPPAILG--------AAVALPGPPGPPGQPGLPG 1130 G G+PG G PGPPG + G PG GPPG G PG Sbjct: 1252 GEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPG 1300 Score = 353 bits (907), Expect = 5e-97 Identities = 252/643 (39%), Positives = 293/643 (45%), Gaps = 107/643 (16%) Query: 517 PLITAGGEESGSPP----PDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGE 572 P T+GG+ PP P GP P+ P+ P ++ G+ G G +GE G G+ Sbjct: 902 PKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD--GLPGHPGQRGETGFQGK 959 Query: 573 ELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGI 632 GPP P G VGP G E +G E+ GPPGPPG GLPG Sbjct: 960 T--GPPGPGGVVGPQ-GPTGETGPIG---------------ERGHPGPPGPPGEQGLPGA 1001 Query: 633 PGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGE 692 GK G GP G G+DGPAG G PG G PG GA GL G +G +G GP GS GE Sbjct: 1002 AGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGE 1061 Query: 693 KGDPGNRG---LPGPPGKKGQAGPPGVMGPPGPPGPPGP------------PGPGCTMGL 737 +G G G LPG PG +G GP G G PG GP GP PGP G Sbjct: 1062 RGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS 1121 Query: 738 GFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGA----SIVGPPGPRG 793 ED G + EP G KG+KG+ GP G G+ G I G G G Sbjct: 1122 PGED----GDKGEIGEPGQK------GSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPG 1171 Query: 794 PPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPG 853 P G + GF GPPGP GL GLPG PG +G GD G G PG Sbjct: 1172 PRGQQGMFGQKGDEGARGFP---------GPPGPIGLQGLPGPPGEKGENGDVGPMGPPG 1222 Query: 854 LKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGR 913 G +G +G GA G +G PG G+ G +G KG PG E G PG PG Sbjct: 1223 PPGPRGPQGPNGAD-----------GPQGPPGSVGSVGGVGEKGEPG---EAGNPGPPGE 1268 Query: 914 PGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAH 973 G+ G KG +G+ G GPPG GPPG GPPG KG P+ P D Sbjct: 1269 AGVGGPKGERGEKGEA--GPPGAAGPPGAKGPPGDD-GPKGNPGPVG------FPGDPGP 1319 Query: 974 PGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDK 1033 PG P GV G+KG G PG G G G GPPGPP G G + Sbjct: 1320 PGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPP--------GKRGPPGAAGAE 1371 Query: 1034 GFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPG-FGRP 1092 G +GEKG KG+ +G G PG GP G +G G GP G G+PGP G G P Sbjct: 1372 GRQGEKGAKGE-------AGAEGPPGKTGPVGPQGP--AGKPGPEGLRGIPGPVGEQGLP 1422 Query: 1093 GDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNLV 1135 G G GPPGP GPP + G L G PG G+ G PG L+ Sbjct: 1423 GAAGQDGPPGPMGPPGLPG----LKGDPGSKGEKGHPGLIGLI 1461 Score = 337 bits (864), Expect = 5e-92 Identities = 245/635 (38%), Positives = 288/635 (45%), Gaps = 125/635 (19%) Query: 515 EEPLITAGGEES--GSPPPDG-----PPLPLPTVAPERWITPAQREHVGMKGQAGPKG-- 565 E+ L A G+E G P P G P L ER + AQ G+KG GP+G Sbjct: 995 EQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP-GLKGGEGPQGPP 1053 Query: 566 -------EKGDAGEE----LPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSE 614 E+G AG LPG P P GP GP A G G G Sbjct: 1054 GPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG-------- 1105 Query: 615 QLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGL 674 ++GP G PGP G G PG+ G +G PG G G GE GPPGP G G GA G+ Sbjct: 1106 --VQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGI 1163 Query: 675 PGMKGEKGARGPNGSVGEKGDPGNRG------------LPGPPGKKGQAGPPGVMGPPGP 722 G GE G RG G G+KGD G RG LPGPPG+KG+ G G MGPPGP Sbjct: 1164 AGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGP 1223 Query: 723 PGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDG 782 PGP GP GP G + +G + ++G GEKG+ G G G G Sbjct: 1224 PGPRGPQGPN-----GADGPQGPPGS-----------VGSVGGVGEKGEPGEAGNPGPPG 1267 Query: 783 -ASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRG 841 A + GP G RG G GPPG G PG G PG G Sbjct: 1268 EAGVGGPKGERGEKGE------------------------AGPPGAAGPPGAKGPPGDDG 1303 Query: 842 PKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGH 901 PKG+ G GFPG + G GEPG + + ++ G+ G+PG G PGP G GPPG Sbjct: 1304 PKGNPGPVGFPG---DPGPPGEPGPAGQDGVGGDK--GEDGDPGQPGPPGPSGEAGPPGP 1358 Query: 902 KGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPG--AVINIKGAIFPI 959 G+ G PG G G G KG KG+ G +GPPG GP GP GP G ++G P+ Sbjct: 1359 PGKRGPPGAAGAEGRQGEKGAKGEAGA--EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV 1416 Query: 960 PVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYL 1019 + +P G P + G+ G KG PGSKGEKG G G GPP + Sbjct: 1417 GEQG---LPGAAGQDGPPGPMGPPGLPGLKGD---PGSKGEKGHPGLIGLIGPPGE---- 1466 Query: 1020 RHFLNNLKGENGDKGFKGEKGE---KGDIN-----GSFLMSGPPGLPGNPGPAGQKGETV 1071 +GE GD+G G +G KGD G GPPGLPG GP G KG T Sbjct: 1467 -------QGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST- 1518 Query: 1072 VGPQGPPGAPGLPGPPGFGRPGDPGPPGPPGPPGP 1106 GP G G GLPGPPG PGPPG P P Sbjct: 1519 -GPAGQKGDSGLPGPPG-----SPGPPGEVIQPLP 1547 Score = 286 bits (731), Expect = 1e-76 Identities = 223/610 (36%), Positives = 259/610 (42%), Gaps = 99/610 (16%) Query: 400 PGPDNEERLAATAAGEA-------EALASMPGEVEASGVAPGELDLSMSAQSLGEEATVG 452 PGP E+ L A E + ++ G G PGE L + + G + G Sbjct: 990 PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGF-PGERGLPGAQGAPGLKGGEG 1048 Query: 453 PSSEDSLTTAAAATEVSLSTFEDEEASGVPTDGLAPLTATMAPERAVTSGPGDEEDLAAA 512 P + E T G L P+ PG + A Sbjct: 1049 PQGPPGPVGSPG------------ERGSAGTAGPIGLPGRPGPQ----GPPGPAGEKGAP 1092 Query: 513 TTEEPLITAGGEESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGE 572 + P AG + G P G P P +P + G G+ G KG KGD GE Sbjct: 1093 GEKGPQGPAGRD--GVQGPVGLPGPAGPAG-----SPGEDGDKGEIGEPGQKGSKGDKGE 1145 Query: 573 E-LPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGS--EQLLRGPPGPPGPPGL 629 PGPP GPVG A G G G G + G ++ RG PGPPGP GL Sbjct: 1146 NGPPGPPGLQGPVG------APGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGL 1199 Query: 630 PGIPGKPGT-----DVF-MGPPGSPGEDGPAGEPGPPGPEGQPGVDGATG---------- 673 G+PG PG DV MGPPG PG GP G G GP+G PG G+ G Sbjct: 1200 QGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGE 1259 Query: 674 --LPGMKGEKGARGPNGSVGEKGD---------PGNRGLPGPPGKKGQAGPPGVMGPPGP 722 PG GE G GP G GEKG+ PG +G PG G KG GP G G PGP Sbjct: 1260 AGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGP 1319 Query: 723 PGPPGPPGPGCTMGLGFEDTE--------GSGSTQLLNEPKLSRPTAAIGLKGEKGDRGP 774 PG PGP G G ED + SG P P A G +G +G++G Sbjct: 1320 PGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGA 1379 Query: 775 KGERGMDG-ASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGL 833 KGE G +G GP GP+GP G G IP GP G GLPG Sbjct: 1380 KGEAGAEGPPGKTGPVGPQGPAG------------KPGPEGLRGIP---GPVGEQGLPGA 1424 Query: 834 PGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLER-LMGKKGEPGMHGAPGP 892 G GP GP G GLPG G G +GEKG PG I P E+ G +G PG G+PG Sbjct: 1425 AGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGA 1484 Query: 893 MGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQ-GPPGLPGPPGPPGPPGAVIN 951 G G PG G G PG PG PG G KG KG G Q G GLPGPPG PGPPG VI Sbjct: 1485 KGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQ 1544 Query: 952 IKGAIFPIPV 961 P+P+ Sbjct: 1545 ------PLPI 1548 Score = 208 bits (529), Expect = 3e-53 Identities = 140/369 (37%), Positives = 162/369 (43%), Gaps = 69/369 (18%) Query: 555 VGMKGQAGPKGEKGDAGEE----LPGPPEPSGPVGPTA--------------------GA 590 +G++G GP GEKG+ G+ PGPP P GP GP G Sbjct: 1197 IGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGE 1256 Query: 591 EAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPG------KPGTDVFMGP 644 E G + G G E+ GPPG GPPG G PG PG F G Sbjct: 1257 PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGD 1316 Query: 645 PGSPGEDGPAGE------------PGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGE 692 PG PGE GPAG+ PG PGP G G G G PG +G GA G G GE Sbjct: 1317 PGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGE 1376 Query: 693 KGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLN 752 KG G G GPPGK G GP G G PGP G G PGP GL G+ Sbjct: 1377 KGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGL-------PGAAGQDG 1429 Query: 753 EPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGF 812 P P GLKG+ G +G KG G+ G ++GPPG +G G + T G Sbjct: 1430 PPGPMGPPGLPGLKGDPGSKGEKGHPGLIG--LIGPPGEQGEKGDRGLPG------TQGS 1481 Query: 813 MNFSDIPELVGPPGPDGLPGLPGFPGPRGPKG------------DTGLPGFPGLKGEQGE 860 + GP GP G PG PG PGP+GPKG D+GLPG PG G GE Sbjct: 1482 PGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGE 1541 Query: 861 KGEPGAILT 869 +P IL+ Sbjct: 1542 VIQPLPILS 1550 Score = 204 bits (520), Expect = 4e-52 Identities = 153/418 (36%), Positives = 180/418 (43%), Gaps = 123/418 (29%) Query: 767 GEKGDRGPKGERGM--DGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGP 824 G G++G KGE + G + GPPGP GP G ++GP Sbjct: 420 GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAG------------------------IMGP 455 Query: 825 PGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEP 884 PG G G PG PG RGP PG PGL G G G PG +L P Sbjct: 456 PGLQGPTGPPGDPGDRGP------PGRPGLPGADGLPGPPGTMLML-------------P 496 Query: 885 GMHGAPGPMGP--------------------KGPPGHKGEFGLPGRPGRPGLNGLKGTKG 924 +G G GP +GPPG G G PG G PG +G KG G Sbjct: 497 FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 556 Query: 925 DPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHG 984 DPG QGP G+ GPPGP G PG R PG P G Sbjct: 557 DPGP--QGPRGVQGPPGPTGKPGK-------------RGRPGADGGRGMPGEP------G 595 Query: 985 VKGEKGSWGLPG---SKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGE 1041 KG++G GLPG KG +G++G QGPPGPP D + ++GE+G+ G +G GE Sbjct: 596 AKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGD--------DGMRGEDGEIGPRGLPGE 647 Query: 1042 KGDINGSFLMSGPPGLPGNPGPAGQKG----ETVVGPQGPPGAPG---------LPGPPG 1088 G G G PG PG PG AG G + +GPQG PG PG LPGP G Sbjct: 648 AGP-RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 706 Query: 1089 -FGRPGDPGPPGPPG---------PPGPPAILGAA--VALPGPPGPPGQPGLPGSRNL 1134 G PG+ GP G PG PPG P G + GPPGP G G PG R + Sbjct: 707 PIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGV 764 Score = 155 bits (393), Expect = 2e-37 Identities = 133/397 (33%), Positives = 162/397 (40%), Gaps = 49/397 (12%) Query: 363 GLAEVPISTAGEAEASSVPTGGPTLSMSTENPE-EGVTPGPDNEERLAATAAGEAEALAS 421 GL +P + E V GP P+ GP + G E Sbjct: 1198 GLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK--G 1255 Query: 422 MPGEVEASGVAPGELDLSMSAQSLGEEATVGPSSEDSLTTAAAATEVSLSTFEDEEASGV 481 PGE G PGE + GE+ GP AA + D+ G Sbjct: 1256 EPGEAGNPG-PPGEAGVGGPKGERGEKGEAGPPG-------AAGPPGAKGPPGDDGPKGN 1307 Query: 482 PTDGLAPLTATMAPERAVTSGPGDEEDLAAATTEEPLITAGGE--ESGSPPPDGPPLPLP 539 P P+ P GP ++ + GG+ E G P GPP P Sbjct: 1308 P----GPVGFPGDPGPPGEPGPAGQDGV------------GGDKGEDGDPGQPGPPGPSG 1351 Query: 540 TVAPERWITPAQREH---VGMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEG-S 595 P P +R G +G+ G KG KG+AG E GPP +GPVGP A G Sbjct: 1352 EAGPPG--PPGKRGPPGAAGAEGRQGEKGAKGEAGAE--GPPGKTGPVGPQGPAGKPGPE 1407 Query: 596 GL-GWGSDVGS-GSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPG------S 647 GL G VG G G + GPPGP GPPGLPG+ G PG+ G PG Sbjct: 1408 GLRGIPGPVGEQGLPGAAGQD----GPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGP 1463 Query: 648 PGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGK 707 PGE G G+ G PG +G PG G G+PG G G GP G G +G GN+G GP G+ Sbjct: 1464 PGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQ 1523 Query: 708 KGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEG 744 KG +G PG G PGPPG P P + TEG Sbjct: 1524 KGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEG 1560 Score = 35.8 bits (81), Expect = 0.29 Identities = 21/66 (31%), Positives = 27/66 (40%), Gaps = 5/66 (7%) Query: 1074 PQGPPG---APGLPGPPGFGRPG--DPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGL 1128 P PP PG+P G G G G PA++ + + GPPGP G G+ Sbjct: 393 PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGI 452 Query: 1129 PGSRNL 1134 G L Sbjct: 453 MGPPGL 458 >gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo sapiens] Length = 1691 Score = 398 bits (1022), Expect = e-110 Identities = 278/681 (40%), Positives = 319/681 (46%), Gaps = 110/681 (16%) Query: 525 ESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSGPV 584 + G P P GPP P + VG GQ GP G G G + GPP P G Sbjct: 776 DRGFPGPPGPPGRTGLDG-----LPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIP 830 Query: 585 GPTAGAEAEGSGLGWGSDVGSGSGDLVG-----SEQLLRGPPGPPGPPGLPGIPGKPGTD 639 GP G G D G D+ G + G PGP GPPG PG+PGK G Sbjct: 831 GPIGQPGLHGIP-GEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS 889 Query: 640 VF---------MGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARG----- 685 F MGPPG PG G G G PG +G G+ G GLPG GEKG++G Sbjct: 890 GFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLP 949 Query: 686 -------PN--GSVGEKGDPG------------NRGLPGPPGKKGQAGPPGVMGPPGPPG 724 PN GS GEKG+PG +GLPG PG+ G +G PG+ GPPGP G Sbjct: 950 GPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKG 1009 Query: 725 PPGPPG-PGCTMGLGFEDTEGS----GSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERG 779 PG PG PG G + T G G + P S G G G +G KG+ G Sbjct: 1010 NPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPG 1069 Query: 780 MDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGP 839 + + G PGP+G PG N I + G +P G G GLPG PG PGP Sbjct: 1070 ISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGP 1129 Query: 840 RGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPP 899 GPKG +G PG PGL GE G G G P G+KG+PG G PGP G KG P Sbjct: 1130 PGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPP-----GEKGKPGQDGIPGPAGQKGEP 1184 Query: 900 GHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPG------------PPGPPG 947 G G FG PG PG PGL+G KG G PG+ G PGLPGP G PPGPPG Sbjct: 1185 GQPG-FGNPGPPGLPGLSGQKGDGGLPGI--PGNPGLPGPKGEPGFHGFPGVQGPPGPPG 1241 Query: 948 AVINIKGAIFPIPVRPHCK-MPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGA 1006 + P P K P PG P F G+ G +G GLPG+ G KG++G Sbjct: 1242 S---------PGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGN 1292 Query: 1007 QGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQ 1066 G PG P L LKG+ G G +G G G +NG M G PGLPG PG G Sbjct: 1293 PGQPGLP--------GLPGLKGDQGPPGLQGNPGRPG-LNG---MKGDPGLPGVPGFPGM 1340 Query: 1067 KGETVV----GPQGPPGAPGLPGPPGFGRP--------GDPGPPGPPGPPGPPAILG--A 1112 KG + V GP+G PG G PGPPG P GD GPPG PG PG + G Sbjct: 1341 KGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQG 1400 Query: 1113 AVALPGPPGPPGQP---GLPG 1130 LPGP GPPG P GLPG Sbjct: 1401 PQGLPGPTGPPGDPGRNGLPG 1421 Score = 382 bits (980), Expect = e-105 Identities = 271/709 (38%), Positives = 309/709 (43%), Gaps = 195/709 (27%) Query: 549 PAQREHVGMKGQAGPKGEKGDAGEE----LPGPPEPSGPVGPTAGAEAEGSGLGWGSDVG 604 P H G+ G GP+G G G++ +PGPP P G Sbjct: 53 PGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKG---------------------- 90 Query: 605 SGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEG 664 +RGPPG PG PG PG+PG PG D GP G PG +G GE G PG G Sbjct: 91 ------------IRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPG 138 Query: 665 QPGVD---GATGLPGMKGEKGA------RGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPG 715 PG+ G G+PGMKGE G+ GP G+ G G PG +GLPGP G G GPPG Sbjct: 139 FPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPG 198 Query: 716 VMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEP-----KLSRPTAAIGLKGEKG 770 G GPPGPPG PGP MGL F+ +G Q L P ++S I ++ +KG Sbjct: 199 PPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKG 258 Query: 771 DRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPD-- 828 D+G G+RG GPPG RGPPG G P G PG D Sbjct: 259 DQGLPGDRGPP-----GPPGIRGPPGP--------PGGEKGEKGEQGEPGKRGKPGKDGE 305 Query: 829 -GLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTE-----------DIPLER 876 G PG+PG PG G G+ G G G KG+ G G PG ++ +I L Sbjct: 306 NGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPG 365 Query: 877 LMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGL 936 L G+KGE G G GP G GPPG G PG PG PG G KG +G PG+ + GPPGL Sbjct: 366 LPGEKGERGFPGIQGPPGLPGPPG-AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGL 424 Query: 937 PGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSP---------ELITFHGVKG 987 G PG PG PG P P PH + PG P L GVKG Sbjct: 425 DGQPGAPGLPGP---------PGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKG 475 Query: 988 EK----------------------------GSWGLPGSKGEKGDQGAQGPPGPPLDLAYL 1019 +K GS G PG KGEKG GA GP G P Sbjct: 476 DKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLP------ 529 Query: 1020 RHFLNNLKGENGDKGFKGEKGEKGDI---------NGSFLMSGPPGLPGNPGPAGQ---- 1066 + G G GF G KGE GDI G G PGLPG PG GQ Sbjct: 530 -----GIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLP 584 Query: 1067 -----KGE----TVVGPQGPPGAPGLP---------GPPGFGRP------------GDPG 1096 KGE T G +GPPG PGLP GPPGFG P G+PG Sbjct: 585 GLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPG 644 Query: 1097 PPGPPGP----------PGPPAILG-----AAVALPGPPGPPGQPGLPG 1130 PG PGP PG P + G V LPG PG PGQPGLPG Sbjct: 645 QPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPG 693 Score = 375 bits (963), Expect = e-103 Identities = 288/719 (40%), Positives = 326/719 (45%), Gaps = 161/719 (22%) Query: 527 GSPPPDG-PPLPLPTVAPERWITPAQREHVGMKGQAGPKG---EKGDAGEELPGPPEPSG 582 G P P G P +P P AP TP + +G++G GP G KG+ G LPGPP P G Sbjct: 710 GPPGPKGFPGIPGPPGAPG---TPGR---IGLEGPPGPPGFPGPKGEPGFALPGPPGPPG 763 Query: 583 PVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFM 642 G +G RG PGPPGPPG G+ G PG + Sbjct: 764 LPGFKGALGPKGD----------------------RGFPGPPGPPGRTGLDGLPGPKGDV 801 Query: 643 GPPGSPGEDGPAGEPG-----PPGPEGQPGVDGATGLPGMKGEKGARGPNG-----SVGE 692 GP G PG GP G PG PPGP G PG G GL G+ GEKG GP G GE Sbjct: 802 GPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGE 861 Query: 693 KGDPGNRGLPGP---------PGKKGQAGPPG------VMGPPGPPGPPGPPGPGCTMGL 737 +G PG G PGP PGK G +G PG +MGPPGPPGP G PG GL Sbjct: 862 RGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGL 921 Query: 738 GFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGP-----------KGERGMDGASIV 786 G L +P L PT G KGE G GP KGE+G G + Sbjct: 922 -------KGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPG--LP 972 Query: 787 GPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPG----------- 835 G PG GP G+ + + G S P L GPPGP G PGLPG Sbjct: 973 GIPGVSGPKGYQGLPGDP------GQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLK 1026 Query: 836 -------FPGPRG------PKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKG 882 FPGP+G P G G PG PGL G++G+KG+PG I L L G KG Sbjct: 1027 GTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGI---SSIGLPGLPGPKG 1083 Query: 883 EPGMHGAPGPMGPKGPPGHKGEFGLPGRPG---RPGLNGLKGTKGDPGVI-MQGPPG--- 935 EPG+ G PG G KG G G GLPG PG +PGL G GT G PG + GPPG Sbjct: 1084 EPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPG 1143 Query: 936 LPGPPGP---------PGPPG--AVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHG 984 LPG PGP PGPPG G P + P +PG P L G Sbjct: 1144 LPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQP-GFGNPGPPGLPGLSG 1202 Query: 985 VKGE------KGSWGLPGSKGEKGDQG---AQGPPGPPLDLAYLRHFLNNLKGENGDKGF 1035 KG+ G+ GLPG KGE G G QGPPGPP L KG G +G Sbjct: 1203 QKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPA---LEGPKGNPGPQGP 1259 Query: 1036 KGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGET----------VVGPQGPPGAPGLPG 1085 G G G G GPPGLPGN G G+KG + G QGPPG G PG Sbjct: 1260 PGRPGPTG-FQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPG 1318 Query: 1086 PPGF----GRPGDPGPPGPPGPPGPPAILGAA-----VALPGPPGPPGQPGLPGSRNLV 1135 PG G PG PG PG PG GP + G+A L GPPGPPG PG G ++ Sbjct: 1319 RPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIII 1377 Score = 374 bits (959), Expect = e-103 Identities = 279/701 (39%), Positives = 310/701 (44%), Gaps = 126/701 (17%) Query: 527 GSPPPDGPP----LPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEP-- 580 G+P GPP LP PT P P +G G G G KG+ G GP Sbjct: 171 GNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKG 230 Query: 581 ----SGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKP 636 GP GP + + DV GD Q L G GPPGPPG+ G PG P Sbjct: 231 EQGLQGPPGPPGQISEQKRPI----DVEFQKGD-----QGLPGDRGPPGPPGIRGPPGPP 281 Query: 637 GTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDP 696 G + G G GE G G+PG G GQPG+ G G PG GE G G G G+ G P Sbjct: 282 GGE--KGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPP 339 Query: 697 -------------------GNRGLPGPPGKKGQAGPPGVMGPPGPPGPP-----GPPG-P 731 GN GLPG PG+KG+ G PG+ GPPG PGPP GPPG P Sbjct: 340 GPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPP 399 Query: 732 GCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGP 791 G G + EG + P L A GL G G GP D GPPGP Sbjct: 400 GFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPS-DEICEPGPPGP 458 Query: 792 RGPPGHIKVLSNSLINITHGFMNFSDI-PELVGPPGPDGLPGLP------GFPGPR---- 840 G PG + + G F+ I + GPPG GLPGLP GFPG + Sbjct: 459 PGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKG 518 Query: 841 -----GPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGE------------ 883 GPKG G+PG PG G G KGEPG ILT + G KGE Sbjct: 519 QAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILT----FPGMKGDKGELGSPGAPGLPGL 574 Query: 884 ---PGMHGAPGPMGPKGPPG---HKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGP---- 933 PG G PG GPKG PG KGE G PG PG PGL G G G PG GP Sbjct: 575 PGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEK 634 Query: 934 --------PGLPGPPGPPGPPGAVINIKGAIFPIPVRP----HCKMPVDTAHPGSPELIT 981 PG PG PGP G PG I G +P P +P D PG P L Sbjct: 635 GIQGVAGNPGQPGIPGPKGDPGQTITQPGKP-GLPGNPGRDGDVGLPGDPGLPGQPGLPG 693 Query: 982 FHGVKGEKG--SWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEK 1039 G KGE G GLPG G KG G GPPG P + L+G G GF G K Sbjct: 694 IPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRI-----GLEGPPGPPGFPGPK 748 Query: 1040 GEKGDINGSFLMSGPPGLPGNP------GPAGQKGETVVGPQGPPGAPGLPGPPGFGRPG 1093 GE G F + GPPG PG P GP G +G GP GPPG GL G P G G Sbjct: 749 GEPG-----FALPGPPGPPGLPGFKGALGPKGDRG--FPGPPGPPGRTGLDGLP--GPKG 799 Query: 1094 DPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNL 1134 D GP G PGP GPP + G + + GPPGPPG PG G L Sbjct: 800 DVGPNGQPGPMGPPGLPG--IGVQGPPGPPGIPGPIGQPGL 838 Score = 364 bits (935), Expect = e-100 Identities = 299/837 (35%), Positives = 356/837 (42%), Gaps = 159/837 (18%) Query: 384 GPTLSMSTENPEEGVTPGPDNEERLAATAAGEAEALASMPGEVEASGVAPGELDLSMSAQ 443 GP E E+G P + + +PG+ G PG Sbjct: 276 GPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPG-EPGR------DG 328 Query: 444 SLGEEATVGPSSEDSLTTAAAATEVSLSTFEDEEASGVPTD-------GLAPLTATMAPE 496 G++ GP L T +++ + G+P + G+ P Sbjct: 329 EKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPP 388 Query: 497 RAVTSGP-------------GDEEDLAAATTEEPLITAGGEESGSPPPDGPPLPL-PTVA 542 A GP GDE + P + + G+P GPP P P + Sbjct: 389 GAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG---QPGAPGLPGPPGPAGPHIP 445 Query: 543 PERWIT-------PAQREHVGMKGQAGPKGEKGDA-----GEELPGPPEPSGPVGPTAGA 590 P I P G++G+ G KG+KGD G + GPP G G Sbjct: 446 PSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPG----LPGL 501 Query: 591 EAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGE 650 LG+ G + L G PG PG PG PG G+PG + PG G+ Sbjct: 502 PGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTF--PGMKGD 559 Query: 651 DGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQ 710 G G PG PG G PG G GLPG+ G KG G GE+G PGN GLPG PG G Sbjct: 560 KGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGP 619 Query: 711 AGPPGVMGPPGP------------PGPPGPPGPGCTMGL--------GFEDTEG-SGSTQ 749 GPPG GPPGP PG PG PGP G G G G Sbjct: 620 MGPPG-FGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVG 678 Query: 750 LLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINIT 809 L +P L G G G G KGE G+ G + GPPGP+G PG I Sbjct: 679 LPGDPGLP------GQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPG---------IPGP 723 Query: 810 HGFMNFSDIPELVGPPGPDGLPGLPGFPGPR--GPKGDTGLPGFPGLKGEQGEKGEPGAI 867 G L GPPGP G PG G PG GP G GLPGF G G +G++G PG Sbjct: 724 PGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPP 783 Query: 868 LTED-IPLERLMGKKGEPGMHGAPGPMGPKGPPG-----HKGEFGLPGRPGRPGLNGLKG 921 L+ L G KG+ G +G PGPMGP G PG G G+PG G+PGL+G+ G Sbjct: 784 GPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPG 843 Query: 922 TKGDPGVIMQGPPGL--PGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPEL 979 KGDPG PPGL PGPPG G PG I GA P P+ P PGSP Sbjct: 844 EKGDPG-----PPGLDVPGPPGERGSPG----IPGA--PGPIGP----------PGSP-- 880 Query: 980 ITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENG---DKGFK 1036 G+ G+ G+ G PG+KGE G G GPPGP L + R + LKG++G G Sbjct: 881 ----GLPGKAGASGFPGTKGEMGMMGPPGPPGP-LGIPG-RSGVPGLKGDDGLQGQPGLP 934 Query: 1037 GEKGEKGDINGSFLMSGPPGLPGNPGPA-----GQKGETVVGPQGPPGAPGLPGPPGF-G 1090 G GEKG G PGLPG PGP G KGE G G PG PG+ GP G+ G Sbjct: 935 GPTGEKGS-------KGEPGLPGPPGPMDPNLLGSKGEK--GEPGLPGIPGVSGPKGYQG 985 Query: 1091 RPGDPGPPGPPGPPGPPAILGAAVALPGPPGP------PGQPGLPGSRNLVTAFSNM 1141 PGDPG PG G PG LPGPPGP PGQPGL G L +M Sbjct: 986 LPGDPGQPGLSGQPG----------LPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDM 1032 Score = 360 bits (925), Expect = 4e-99 Identities = 257/654 (39%), Positives = 297/654 (45%), Gaps = 144/654 (22%) Query: 525 ESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAG---PKGEKGDAGEELPGPPEPS 581 E G P GPP PL P R P + G++GQ G P GEKG GE PG P P Sbjct: 897 EMGMMGPPGPPGPLGI--PGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGE--PGLPGPP 952 Query: 582 GPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVF 641 GP+ P L G G G PGLPGIPG G + Sbjct: 953 GPMDPN-----------------------------LLGSKGEKGEPGLPGIPGVSGPKGY 983 Query: 642 MGPPGSPGEDGPAGE---PGPPGPEGQPGVDGATGL---PGMKGE------KGARGPNGS 689 G PG PG+ G +G+ PGPPGP+G PG+ G GL PG+KG G +G G Sbjct: 984 QGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGP 1043 Query: 690 VGEKGDPGNRGLPGPPGKKGQAGPPGV--MGPPGPPGPPGPPG-PGCTMGLGFEDTEGS- 745 G G PG G PG PG+KG G PG+ +G PG PGP G PG PG G + + G Sbjct: 1044 PGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDP 1103 Query: 746 GSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDG-ASIVGPPGPRGPPGHIKVLSNS 804 G L P G G G GPKG G G + G PGP G GH Sbjct: 1104 GLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGH------- 1156 Query: 805 LINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGF--------PGLKG 856 P GPPG G PG G PGP G KG+ G PGF PGL G Sbjct: 1157 --------------PGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSG 1202 Query: 857 EQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPP-----------GHKGEF 905 ++G+ G PG +P G KGEPG HG PG GP GPP G+ G Sbjct: 1203 QKGDGGLPGIPGNPGLP-----GPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ 1257 Query: 906 GLPGRPGRPGLNGLKGTKGDPGVI----MQGPPGLPGPPGPPGPPGAVINIKGAIFPIPV 961 G PGRPG G GL G +G PG+ ++G G PG PG PG PG +KG P + Sbjct: 1258 GPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPG----LKGDQGPPGL 1313 Query: 962 RPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRH 1021 + + P G P L G G KG G+PGS G +G+ G GPPGPP Sbjct: 1314 QGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPP-------- 1365 Query: 1022 FLNNLKGENGDK-GFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGA 1080 L G +G KG+ G G + G PGL G PGP G +G + GP GPPG Sbjct: 1366 ---GLPGPSGQSIIIKGDAGPPG-------IPGQPGLKGLPGPQGPQG--LPGPTGPPGD 1413 Query: 1081 PGLPGPPGF----GRPGDPGPPGPP------GPPGPPAILGAAVALPGPPGPPG 1124 PG G PGF GR GDPG PG P GPPGP L GPPGPPG Sbjct: 1414 PGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPD-------GLQGPPGPPG 1460 Score = 357 bits (915), Expect = 6e-98 Identities = 277/752 (36%), Positives = 327/752 (43%), Gaps = 175/752 (23%) Query: 525 ESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSGPV 584 E G GPP P ++ Q+ + ++ Q G +G GD G PGPP GP Sbjct: 228 EKGEQGLQGPPGPPGQISE-------QKRPIDVEFQKGDQGLPGDRGP--PGPPGIRGPP 278 Query: 585 GPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGP 644 GP G + E G G D + + G PG PG PG PG G+ G GP Sbjct: 279 GPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGP 338 Query: 645 PGSPG-------------EDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGAR-----GP 686 PG PG E G G PG PG +G+ G G G PG+ G GA GP Sbjct: 339 PGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGP 398 Query: 687 NGSVGEKGDPGNRG-----LPGPPGKKGQAGPPGVMGPPGP-------------PGPPGP 728 G GE+G G+ G +PGPPG GQ G PG+ GPPGP PGPPGP Sbjct: 399 PGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGP 458 Query: 729 PGPGCTMGL----GFEDTEG-----------SGSTQLLNEPKLSRPTAAIGLKGEKGDRG 773 PG GL G + +G SG P L P ++G G+KG++G Sbjct: 459 PGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKG 518 Query: 774 ------PKGERGMDGA-SIVGPPGPRGPPGHIKVLSNSLINITH-GFMNFSDIPELVGPP 825 PKG G+ GA G PG +G PG I + G +P L G P Sbjct: 519 QAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTP 578 Query: 826 GPDGLPGLPG---------FPGPRGPKGDTGLPGFPGLKGEQGEKG--EPGAILTEDIPL 874 G DGLPGLPG F G RGP G+ GLPG PG G G G PG + + I Sbjct: 579 GQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGI-- 636 Query: 875 ERLMGKKGEPGMHGAPGPMGPKGP-------------PGHKGEFGLPGRPG---RPGLNG 918 G G PG G PGP G G PG G+ GLPG PG +PGL G Sbjct: 637 ---QGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPG 693 Query: 919 LKGTKGDPGVIMQGPPGLPGP---PGPPGPPGAV-----INIKGAIFPIPVRPHCKMPVD 970 + G+KG+PG+ G PG PGP PG PGPPGA I ++G P P P K Sbjct: 694 IPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGP-PGFPGPKGEPG 752 Query: 971 TAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGEN 1030 A PG P G G G G+ G KGD+G GPPGPP R L+ L G Sbjct: 753 FALPGPP---------GPPGLPGFKGALGPKGDRGFPGPPGPPG-----RTGLDGLPGPK 798 Query: 1031 GDKGFKGEKGEKGDINGSFL-MSGPPGLPGNPGPAGQKG-ETVVGPQGPPGAPGL--PGP 1086 GD G G+ G G + + GPPG PG PGP GQ G + G +G PG PGL PGP Sbjct: 799 GDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGP 858 Query: 1087 PGF-GRPGDPGPPGPPGPPGPPAILGAAVAL----------------------------- 1116 PG G PG PG PGP GPPG P + G A A Sbjct: 859 PGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGV 918 Query: 1117 ------------PGPPGP------PGQPGLPG 1130 PG PGP G+PGLPG Sbjct: 919 PGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPG 950 Score = 318 bits (815), Expect = 2e-86 Identities = 238/633 (37%), Positives = 273/633 (43%), Gaps = 167/633 (26%) Query: 577 PPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKP 636 P E + G + G++ + SG + E+ RG PG G PGLPG PG Sbjct: 23 PAEAAACYGCSPGSKCDCSG--------------IKGEKGERGFPGLEGHPGLPGFPGPE 68 Query: 637 GTDVFMGPPGSPGEDGPAGEPGPPG---PEGQPGVDGATGLPGMKGEKGARGPNGSVGEK 693 G GP G G+DG G PGP G P G PG G GLPGM G GA GP G G Sbjct: 69 GPP---GPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCN 125 Query: 694 GDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNE 753 G G RG PG PG PG+ GPPGPPG PG G E Sbjct: 126 GTKGERGFPGSPGF------PGLQGPPGPPGIPGMKG----------------------E 157 Query: 754 PKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFM 813 P ++ G KG G GP G +G+ G + G PGP GPPG Sbjct: 158 PGSIIMSSLPGPKGNPGYPGPPGIQGLPGPT--GIPGPIGPPGP---------------- 199 Query: 814 NFSDIPELVGPPGPDGLPGLPG-----FPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAIL 868 P L+GPPGP GLPG G F GP+G KG+ GL G PG G+ E+ P Sbjct: 200 -----PGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRP---- 250 Query: 869 TEDIPLERLMGKKGEPGMHGAPGPMGPKGPPG----HKGEFGLPGRPGRPGLNGLKGTKG 924 I +E G +G PG G PGP G +GPPG KGE G G PG+ G G G G Sbjct: 251 ---IDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENG 307 Query: 925 DPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFH- 983 PG+ PGLPG PG PG PG KG DT PG P L+ Sbjct: 308 QPGI-----PGLPGDPGYPGEPGRD-GEKG------------QKGDTGPPGPPGLVIPRP 349 Query: 984 ------GVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKG 1037 G KG G GLPG KGE+G G QGPPG P + G G GF G Sbjct: 350 GTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAA------VMGPPGPPGFPG 403 Query: 1038 EKGEKGD-------INGSFLMSGPPGLPGNPGPAGQKGETVV--------GPQGPPGAPG 1082 E+G+KGD I G + G PG PG PGP G G + GP GPPG+PG Sbjct: 404 ERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPG 463 Query: 1083 -------------------------LPGPPGF-GRPGDPGPPGPPGPPGPPAILGAAVA- 1115 + GPPG G PG PGPPG G PG G A A Sbjct: 464 DKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGAT 523 Query: 1116 -------LPGPPGPPGQPGLPGSRNLVTAFSNM 1141 +PG PG PG PG G + F M Sbjct: 524 GPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGM 556 Score = 163 bits (413), Expect = 9e-40 Identities = 128/374 (34%), Positives = 146/374 (39%), Gaps = 84/374 (22%) Query: 527 GSPPPDGPP-LPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEE-LPGPPEPSGPV 584 G+P P GP + P P P G GQ GP GEKG G++ +PGP G Sbjct: 1125 GTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEP 1184 Query: 585 GPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGP 644 G GL G G G L G + G PG PGP G PG G PG GP Sbjct: 1185 GQPGFGNPGPPGLP-GLSGQKGDGGLPG----IPGNPGLPGPKGEPGFHGFPGVQGPPGP 1239 Query: 645 PGSPGE--DGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLP 702 PGSPG +GP G PGP GP G+PG G GLPG +G G G G GEKG+PG GLP Sbjct: 1240 PGSPGPALEGPKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLP 1299 Query: 703 GPPGKKGQAGPPGVMGPPGPPG-------------------------------------- 724 G PG KG GPPG+ G PG PG Sbjct: 1300 GLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLI 1359 Query: 725 -PPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSR------PTAAIGLKGEKGDRGPKGE 777 PPGPPG G +G + +P L P G G GD G G Sbjct: 1360 GPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGL 1419 Query: 778 RGMDGAS----------------IVGPPGPR------GPPGHIKVLSNSLINITHGFMNF 815 G DGA + GPPGP GPPG ++ HGF+ Sbjct: 1420 PGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG--------TSSVAHGFLIT 1471 Query: 816 SDIPELVGPPGPDG 829 P P G Sbjct: 1472 RHSQTTDAPQCPQG 1485 Score = 136 bits (343), Expect = 1e-31 Identities = 106/293 (36%), Positives = 121/293 (41%), Gaps = 56/293 (19%) Query: 882 GEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPP------- 934 G+P A P G G G G PGL G G G PG +GPP Sbjct: 21 GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPG--PEGPPGPRGQKG 78 Query: 935 --GLPGPPGPP---GPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEK 989 G+PGPPGP GPPG + P P +P H G+P G G K Sbjct: 79 DDGIPGPPGPKGIRGPPG--------LPGFPGTP--GLPGMPGHDGAPGPQGIPGCNGTK 128 Query: 990 GSWGLPGSKGEKGDQGAQGPPG-PPLDLAYLRHFLNNLKGENGDKGFKGEKGEKG----- 1043 G G PGS G G QG GPPG P + +++L G G+ G+ G G +G Sbjct: 129 GERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPT 188 Query: 1044 DINGSFLMSGPPGL------PGNPGPAGQKGETVVGPQGPPGAPGLPGPPG--------- 1088 I G GPPGL PG PGP G G GP+G G GL GPPG Sbjct: 189 GIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQK 248 Query: 1089 -----------FGRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPG 1130 G PGD GPPGPPG GPP G G G PG+ G PG Sbjct: 249 RPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPG 301 Score = 70.1 bits (170), Expect = 1e-11 Identities = 58/177 (32%), Positives = 72/177 (40%), Gaps = 23/177 (12%) Query: 527 GSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAG-EELPGPPEPSGPVG 585 GS P+G P + P P+ + + +KG AGP G G G + LPGP P G G Sbjct: 1348 GSAGPEGEPGLIGPPGPPGLPGPSGQSII-IKGDAGPPGIPGQPGLKGLPGPQGPQGLPG 1406 Query: 586 PTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPP 645 PT G G D G +G PG PG PG G+ G PG D GPP Sbjct: 1407 PTGPPGDPGRNGLPGFDGAGGR----------KGDPGLPGQPGTRGLDGPPGPDGLQGPP 1456 Query: 646 GSPGEDGPA----------GEPGPPGPEGQPGVDGATGLPGMKGEKGARGPN-GSVG 691 G PG A P P+G V L ++G K A G + G+ G Sbjct: 1457 GPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQVYEGFSLLYVQGNKRAHGQDLGTAG 1513 >gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo sapiens] Length = 1688 Score = 395 bits (1014), Expect = e-109 Identities = 278/681 (40%), Positives = 319/681 (46%), Gaps = 113/681 (16%) Query: 525 ESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSGPV 584 + G P P GPP P + VG GQ GP G G G + GPP P G Sbjct: 776 DRGFPGPPGPPGRTGLDG-----LPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIP 830 Query: 585 GPTAGAEAEGSGLGWGSDVGSGSGDLVG-----SEQLLRGPPGPPGPPGLPGIPGKPGTD 639 GP G G D G D+ G + G PGP GPPG PG+PGK G Sbjct: 831 GPIGQPGLHGIP-GEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS 889 Query: 640 VF---------MGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARG----- 685 F MGPPG PG G G G PG +G G+ G GLPG GEKG++G Sbjct: 890 GFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLP 949 Query: 686 -------PN--GSVGEKGDPG------------NRGLPGPPGKKGQAGPPGVMGPPGPPG 724 PN GS GEKG+PG +GLPG PG+ G +G PG+ GPPGP G Sbjct: 950 GPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKG 1009 Query: 725 PPGPPG-PGCTMGLGFEDTEGS----GSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERG 779 PG PG PG G + T G G + P S G G G +G KG+ G Sbjct: 1010 NPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPG 1069 Query: 780 MDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGP 839 + + G PGP+G PG N I + G +P G G GLPG PG PGP Sbjct: 1070 ISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGP 1129 Query: 840 RGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPP 899 GPKG +G PG PGL GE G G G P G+KG+PG G PGP G KG P Sbjct: 1130 PGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPP-----GEKGKPGQDGIPGPAGQKGEP 1184 Query: 900 GHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPG------------PPGPPG 947 G G FG PG PG PGL+G KG G PG+ G PGLPGP G PPGPPG Sbjct: 1185 GQPG-FGNPGPPGLPGLSGQKGDGGLPGI--PGNPGLPGPKGEPGFHGFPGVQGPPGPPG 1241 Query: 948 AVINIKGAIFPIPVRPHCK-MPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGA 1006 + P P K P PG P F G+ G +G GLPG+ G KG++G Sbjct: 1242 S---------PGPALEGPKGNPGPQGPPGRPG---FQGLPGPEGPPGLPGNGGIKGEKGN 1289 Query: 1007 QGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQ 1066 G PG P L LKG+ G G +G G G +NG M G PGLPG PG G Sbjct: 1290 PGQPGLP--------GLPGLKGDQGPPGLQGNPGRPG-LNG---MKGDPGLPGVPGFPGM 1337 Query: 1067 KGETVV----GPQGPPGAPGLPGPPGFGRP--------GDPGPPGPPGPPGPPAILG--A 1112 KG + V GP+G PG G PGPPG P GD GPPG PG PG + G Sbjct: 1338 KGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQG 1397 Query: 1113 AVALPGPPGPPGQP---GLPG 1130 LPGP GPPG P GLPG Sbjct: 1398 PQGLPGPTGPPGDPGRNGLPG 1418 Score = 382 bits (980), Expect = e-105 Identities = 271/709 (38%), Positives = 309/709 (43%), Gaps = 195/709 (27%) Query: 549 PAQREHVGMKGQAGPKGEKGDAGEE----LPGPPEPSGPVGPTAGAEAEGSGLGWGSDVG 604 P H G+ G GP+G G G++ +PGPP P G Sbjct: 53 PGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKG---------------------- 90 Query: 605 SGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEG 664 +RGPPG PG PG PG+PG PG D GP G PG +G GE G PG G Sbjct: 91 ------------IRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPG 138 Query: 665 QPGVD---GATGLPGMKGEKGA------RGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPG 715 PG+ G G+PGMKGE G+ GP G+ G G PG +GLPGP G G GPPG Sbjct: 139 FPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPG 198 Query: 716 VMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEP-----KLSRPTAAIGLKGEKG 770 G GPPGPPG PGP MGL F+ +G Q L P ++S I ++ +KG Sbjct: 199 PPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKG 258 Query: 771 DRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPD-- 828 D+G G+RG GPPG RGPPG G P G PG D Sbjct: 259 DQGLPGDRGPP-----GPPGIRGPPGP--------PGGEKGEKGEQGEPGKRGKPGKDGE 305 Query: 829 -GLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTE-----------DIPLER 876 G PG+PG PG G G+ G G G KG+ G G PG ++ +I L Sbjct: 306 NGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPG 365 Query: 877 LMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGL 936 L G+KGE G G GP G GPPG G PG PG PG G KG +G PG+ + GPPGL Sbjct: 366 LPGEKGERGFPGIQGPPGLPGPPG-AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGL 424 Query: 937 PGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSP---------ELITFHGVKG 987 G PG PG PG P P PH + PG P L GVKG Sbjct: 425 DGQPGAPGLPGP---------PGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKG 475 Query: 988 EK----------------------------GSWGLPGSKGEKGDQGAQGPPGPPLDLAYL 1019 +K GS G PG KGEKG GA GP G P Sbjct: 476 DKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLP------ 529 Query: 1020 RHFLNNLKGENGDKGFKGEKGEKGDI---------NGSFLMSGPPGLPGNPGPAGQ---- 1066 + G G GF G KGE GDI G G PGLPG PG GQ Sbjct: 530 -----GIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLP 584 Query: 1067 -----KGE----TVVGPQGPPGAPGLP---------GPPGFGRP------------GDPG 1096 KGE T G +GPPG PGLP GPPGFG P G+PG Sbjct: 585 GLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPG 644 Query: 1097 PPGPPGP----------PGPPAILG-----AAVALPGPPGPPGQPGLPG 1130 PG PGP PG P + G V LPG PG PGQPGLPG Sbjct: 645 QPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPG 693 Score = 375 bits (962), Expect = e-103 Identities = 287/719 (39%), Positives = 327/719 (45%), Gaps = 164/719 (22%) Query: 527 GSPPPDG-PPLPLPTVAPERWITPAQREHVGMKGQAGPKG---EKGDAGEELPGPPEPSG 582 G P P G P +P P AP TP + +G++G GP G KG+ G LPGPP P G Sbjct: 710 GPPGPKGFPGIPGPPGAPG---TPGR---IGLEGPPGPPGFPGPKGEPGFALPGPPGPPG 763 Query: 583 PVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFM 642 G +G RG PGPPGPPG G+ G PG + Sbjct: 764 LPGFKGALGPKGD----------------------RGFPGPPGPPGRTGLDGLPGPKGDV 801 Query: 643 GPPGSPGEDGPAGEPG-----PPGPEGQPGVDGATGLPGMKGEKGARGPNG-----SVGE 692 GP G PG GP G PG PPGP G PG G GL G+ GEKG GP G GE Sbjct: 802 GPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGE 861 Query: 693 KGDPGNRGLPGP---------PGKKGQAGPPG------VMGPPGPPGPPGPPGPGCTMGL 737 +G PG G PGP PGK G +G PG +MGPPGPPGP G PG GL Sbjct: 862 RGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGL 921 Query: 738 GFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGP-----------KGERGMDGASIV 786 G L +P L PT G KGE G GP KGE+G G + Sbjct: 922 -------KGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPG--LP 972 Query: 787 GPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPG----------- 835 G PG GP G+ + + G S P L GPPGP G PGLPG Sbjct: 973 GIPGVSGPKGYQGLPGDP------GQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLK 1026 Query: 836 -------FPGPRG------PKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKG 882 FPGP+G P G G PG PGL G++G+KG+PG I L L G KG Sbjct: 1027 GTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGI---SSIGLPGLPGPKG 1083 Query: 883 EPGMHGAPGPMGPKGPPGHKGEFGLPGRPG---RPGLNGLKGTKGDPGVI-MQGPPG--- 935 EPG+ G PG G KG G G GLPG PG +PGL G GT G PG + GPPG Sbjct: 1084 EPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPG 1143 Query: 936 LPGPPGP---------PGPPG--AVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHG 984 LPG PGP PGPPG G P + P +PG P L G Sbjct: 1144 LPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQP-GFGNPGPPGLPGLSG 1202 Query: 985 VKGE------KGSWGLPGSKGEKGDQG---AQGPPGPPLDLAYLRHFLNNLKGENGDKGF 1035 KG+ G+ GLPG KGE G G QGPPGPP L+G G+ G Sbjct: 1203 QKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPA------LEGPKGNPGP 1256 Query: 1036 KGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGET----------VVGPQGPPGAPGLPG 1085 +G G G G GPPGLPGN G G+KG + G QGPPG G PG Sbjct: 1257 QGPPGRPG-FQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPG 1315 Query: 1086 PPGF----GRPGDPGPPGPPGPPGPPAILGAA-----VALPGPPGPPGQPGLPGSRNLV 1135 PG G PG PG PG PG GP + G+A L GPPGPPG PG G ++ Sbjct: 1316 RPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIII 1374 Score = 374 bits (959), Expect = e-103 Identities = 279/701 (39%), Positives = 310/701 (44%), Gaps = 126/701 (17%) Query: 527 GSPPPDGPP----LPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEP-- 580 G+P GPP LP PT P P +G G G G KG+ G GP Sbjct: 171 GNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKG 230 Query: 581 ----SGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKP 636 GP GP + + DV GD Q L G GPPGPPG+ G PG P Sbjct: 231 EQGLQGPPGPPGQISEQKRPI----DVEFQKGD-----QGLPGDRGPPGPPGIRGPPGPP 281 Query: 637 GTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDP 696 G + G G GE G G+PG G GQPG+ G G PG GE G G G G+ G P Sbjct: 282 GGE--KGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPP 339 Query: 697 -------------------GNRGLPGPPGKKGQAGPPGVMGPPGPPGPP-----GPPG-P 731 GN GLPG PG+KG+ G PG+ GPPG PGPP GPPG P Sbjct: 340 GPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPP 399 Query: 732 GCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGP 791 G G + EG + P L A GL G G GP D GPPGP Sbjct: 400 GFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPS-DEICEPGPPGP 458 Query: 792 RGPPGHIKVLSNSLINITHGFMNFSDI-PELVGPPGPDGLPGLP------GFPGPR---- 840 G PG + + G F+ I + GPPG GLPGLP GFPG + Sbjct: 459 PGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKG 518 Query: 841 -----GPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGE------------ 883 GPKG G+PG PG G G KGEPG ILT + G KGE Sbjct: 519 QAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILT----FPGMKGDKGELGSPGAPGLPGL 574 Query: 884 ---PGMHGAPGPMGPKGPPG---HKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGP---- 933 PG G PG GPKG PG KGE G PG PG PGL G G G PG GP Sbjct: 575 PGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEK 634 Query: 934 --------PGLPGPPGPPGPPGAVINIKGAIFPIPVRP----HCKMPVDTAHPGSPELIT 981 PG PG PGP G PG I G +P P +P D PG P L Sbjct: 635 GIQGVAGNPGQPGIPGPKGDPGQTITQPGKP-GLPGNPGRDGDVGLPGDPGLPGQPGLPG 693 Query: 982 FHGVKGEKG--SWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEK 1039 G KGE G GLPG G KG G GPPG P + L+G G GF G K Sbjct: 694 IPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRI-----GLEGPPGPPGFPGPK 748 Query: 1040 GEKGDINGSFLMSGPPGLPGNP------GPAGQKGETVVGPQGPPGAPGLPGPPGFGRPG 1093 GE G F + GPPG PG P GP G +G GP GPPG GL G P G G Sbjct: 749 GEPG-----FALPGPPGPPGLPGFKGALGPKGDRG--FPGPPGPPGRTGLDGLP--GPKG 799 Query: 1094 DPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNL 1134 D GP G PGP GPP + G + + GPPGPPG PG G L Sbjct: 800 DVGPNGQPGPMGPPGLPG--IGVQGPPGPPGIPGPIGQPGL 838 Score = 364 bits (935), Expect = e-100 Identities = 299/837 (35%), Positives = 356/837 (42%), Gaps = 159/837 (18%) Query: 384 GPTLSMSTENPEEGVTPGPDNEERLAATAAGEAEALASMPGEVEASGVAPGELDLSMSAQ 443 GP E E+G P + + +PG+ G PG Sbjct: 276 GPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPG-EPGR------DG 328 Query: 444 SLGEEATVGPSSEDSLTTAAAATEVSLSTFEDEEASGVPTD-------GLAPLTATMAPE 496 G++ GP L T +++ + G+P + G+ P Sbjct: 329 EKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPP 388 Query: 497 RAVTSGP-------------GDEEDLAAATTEEPLITAGGEESGSPPPDGPPLPL-PTVA 542 A GP GDE + P + + G+P GPP P P + Sbjct: 389 GAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG---QPGAPGLPGPPGPAGPHIP 445 Query: 543 PERWIT-------PAQREHVGMKGQAGPKGEKGDA-----GEELPGPPEPSGPVGPTAGA 590 P I P G++G+ G KG+KGD G + GPP G G Sbjct: 446 PSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPG----LPGL 501 Query: 591 EAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGE 650 LG+ G + L G PG PG PG PG G+PG + PG G+ Sbjct: 502 PGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTF--PGMKGD 559 Query: 651 DGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQ 710 G G PG PG G PG G GLPG+ G KG G GE+G PGN GLPG PG G Sbjct: 560 KGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGP 619 Query: 711 AGPPGVMGPPGP------------PGPPGPPGPGCTMGL--------GFEDTEG-SGSTQ 749 GPPG GPPGP PG PG PGP G G G G Sbjct: 620 MGPPG-FGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVG 678 Query: 750 LLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINIT 809 L +P L G G G G KGE G+ G + GPPGP+G PG I Sbjct: 679 LPGDPGLP------GQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPG---------IPGP 723 Query: 810 HGFMNFSDIPELVGPPGPDGLPGLPGFPGPR--GPKGDTGLPGFPGLKGEQGEKGEPGAI 867 G L GPPGP G PG G PG GP G GLPGF G G +G++G PG Sbjct: 724 PGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPP 783 Query: 868 LTED-IPLERLMGKKGEPGMHGAPGPMGPKGPPG-----HKGEFGLPGRPGRPGLNGLKG 921 L+ L G KG+ G +G PGPMGP G PG G G+PG G+PGL+G+ G Sbjct: 784 GPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPG 843 Query: 922 TKGDPGVIMQGPPGL--PGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPEL 979 KGDPG PPGL PGPPG G PG I GA P P+ P PGSP Sbjct: 844 EKGDPG-----PPGLDVPGPPGERGSPG----IPGA--PGPIGP----------PGSP-- 880 Query: 980 ITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENG---DKGFK 1036 G+ G+ G+ G PG+KGE G G GPPGP L + R + LKG++G G Sbjct: 881 ----GLPGKAGASGFPGTKGEMGMMGPPGPPGP-LGIPG-RSGVPGLKGDDGLQGQPGLP 934 Query: 1037 GEKGEKGDINGSFLMSGPPGLPGNPGPA-----GQKGETVVGPQGPPGAPGLPGPPGF-G 1090 G GEKG G PGLPG PGP G KGE G G PG PG+ GP G+ G Sbjct: 935 GPTGEKGS-------KGEPGLPGPPGPMDPNLLGSKGEK--GEPGLPGIPGVSGPKGYQG 985 Query: 1091 RPGDPGPPGPPGPPGPPAILGAAVALPGPPGP------PGQPGLPGSRNLVTAFSNM 1141 PGDPG PG G PG LPGPPGP PGQPGL G L +M Sbjct: 986 LPGDPGQPGLSGQPG----------LPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDM 1032 Score = 363 bits (932), Expect = e-100 Identities = 258/651 (39%), Positives = 297/651 (45%), Gaps = 141/651 (21%) Query: 525 ESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAG---PKGEKGDAGEELPGPPEPS 581 E G P GPP PL P R P + G++GQ G P GEKG GE PG P P Sbjct: 897 EMGMMGPPGPPGPLGI--PGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGE--PGLPGPP 952 Query: 582 GPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVF 641 GP+ P L G G G PGLPGIPG G + Sbjct: 953 GPMDPN-----------------------------LLGSKGEKGEPGLPGIPGVSGPKGY 983 Query: 642 MGPPGSPGEDGPAGE---PGPPGPEGQPGVDGATGL---PGMKGE------KGARGPNGS 689 G PG PG+ G +G+ PGPPGP+G PG+ G GL PG+KG G +G G Sbjct: 984 QGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGP 1043 Query: 690 VGEKGDPGNRGLPGPPGKKGQAGPPGV--MGPPGPPGPPGPPG-PGCTMGLGFEDTEGS- 745 G G PG G PG PG+KG G PG+ +G PG PGP G PG PG G + + G Sbjct: 1044 PGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDP 1103 Query: 746 GSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDG-ASIVGPPGPRGPPGHIKVLSNS 804 G L P G G G GPKG G G + G PGP G GH Sbjct: 1104 GLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGH------- 1156 Query: 805 LINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGF--------PGLKG 856 P GPPG G PG G PGP G KG+ G PGF PGL G Sbjct: 1157 --------------PGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSG 1202 Query: 857 EQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGH--------KGEFGLP 908 ++G+ G PG +P G KGEPG HG PG GP GPPG KG G Sbjct: 1203 QKGDGGLPGIPGNPGLP-----GPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQ 1257 Query: 909 GRPGRPGLNGLKGTKGDPGVI----MQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPH 964 G PGRPG GL G +G PG+ ++G G PG PG PG PG +KG P ++ + Sbjct: 1258 GPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPG----LKGDQGPPGLQGN 1313 Query: 965 CKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLN 1024 P G P L G G KG G+PGS G +G+ G GPPGPP Sbjct: 1314 PGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPP----------- 1362 Query: 1025 NLKGENGDK-GFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGL 1083 L G +G KG+ G G + G PGL G PGP G +G + GP GPPG PG Sbjct: 1363 GLPGPSGQSIIIKGDAGPPG-------IPGQPGLKGLPGPQGPQG--LPGPTGPPGDPGR 1413 Query: 1084 PGPPGF----GRPGDPGPPGPP------GPPGPPAILGAAVALPGPPGPPG 1124 G PGF GR GDPG PG P GPPGP L GPPGPPG Sbjct: 1414 NGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPD-------GLQGPPGPPG 1457 Score = 357 bits (915), Expect = 6e-98 Identities = 277/752 (36%), Positives = 327/752 (43%), Gaps = 175/752 (23%) Query: 525 ESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSGPV 584 E G GPP P ++ Q+ + ++ Q G +G GD G PGPP GP Sbjct: 228 EKGEQGLQGPPGPPGQISE-------QKRPIDVEFQKGDQGLPGDRGP--PGPPGIRGPP 278 Query: 585 GPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGP 644 GP G + E G G D + + G PG PG PG PG G+ G GP Sbjct: 279 GPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGP 338 Query: 645 PGSPG-------------EDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGAR-----GP 686 PG PG E G G PG PG +G+ G G G PG+ G GA GP Sbjct: 339 PGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGP 398 Query: 687 NGSVGEKGDPGNRG-----LPGPPGKKGQAGPPGVMGPPGP-------------PGPPGP 728 G GE+G G+ G +PGPPG GQ G PG+ GPPGP PGPPGP Sbjct: 399 PGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGP 458 Query: 729 PGPGCTMGL----GFEDTEG-----------SGSTQLLNEPKLSRPTAAIGLKGEKGDRG 773 PG GL G + +G SG P L P ++G G+KG++G Sbjct: 459 PGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKG 518 Query: 774 ------PKGERGMDGA-SIVGPPGPRGPPGHIKVLSNSLINITH-GFMNFSDIPELVGPP 825 PKG G+ GA G PG +G PG I + G +P L G P Sbjct: 519 QAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTP 578 Query: 826 GPDGLPGLPG---------FPGPRGPKGDTGLPGFPGLKGEQGEKG--EPGAILTEDIPL 874 G DGLPGLPG F G RGP G+ GLPG PG G G G PG + + I Sbjct: 579 GQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGI-- 636 Query: 875 ERLMGKKGEPGMHGAPGPMGPKGP-------------PGHKGEFGLPGRPG---RPGLNG 918 G G PG G PGP G G PG G+ GLPG PG +PGL G Sbjct: 637 ---QGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPG 693 Query: 919 LKGTKGDPGVIMQGPPGLPGP---PGPPGPPGAV-----INIKGAIFPIPVRPHCKMPVD 970 + G+KG+PG+ G PG PGP PG PGPPGA I ++G P P P K Sbjct: 694 IPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGP-PGFPGPKGEPG 752 Query: 971 TAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGEN 1030 A PG P G G G G+ G KGD+G GPPGPP R L+ L G Sbjct: 753 FALPGPP---------GPPGLPGFKGALGPKGDRGFPGPPGPPG-----RTGLDGLPGPK 798 Query: 1031 GDKGFKGEKGEKGDINGSFL-MSGPPGLPGNPGPAGQKG-ETVVGPQGPPGAPGL--PGP 1086 GD G G+ G G + + GPPG PG PGP GQ G + G +G PG PGL PGP Sbjct: 799 GDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGP 858 Query: 1087 PGF-GRPGDPGPPGPPGPPGPPAILGAAVAL----------------------------- 1116 PG G PG PG PGP GPPG P + G A A Sbjct: 859 PGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGV 918 Query: 1117 ------------PGPPGP------PGQPGLPG 1130 PG PGP G+PGLPG Sbjct: 919 PGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPG 950 Score = 318 bits (815), Expect = 2e-86 Identities = 238/633 (37%), Positives = 273/633 (43%), Gaps = 167/633 (26%) Query: 577 PPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKP 636 P E + G + G++ + SG + E+ RG PG G PGLPG PG Sbjct: 23 PAEAAACYGCSPGSKCDCSG--------------IKGEKGERGFPGLEGHPGLPGFPGPE 68 Query: 637 GTDVFMGPPGSPGEDGPAGEPGPPG---PEGQPGVDGATGLPGMKGEKGARGPNGSVGEK 693 G GP G G+DG G PGP G P G PG G GLPGM G GA GP G G Sbjct: 69 GPP---GPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCN 125 Query: 694 GDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNE 753 G G RG PG PG PG+ GPPGPPG PG G E Sbjct: 126 GTKGERGFPGSPGF------PGLQGPPGPPGIPGMKG----------------------E 157 Query: 754 PKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFM 813 P ++ G KG G GP G +G+ G + G PGP GPPG Sbjct: 158 PGSIIMSSLPGPKGNPGYPGPPGIQGLPGPT--GIPGPIGPPGP---------------- 199 Query: 814 NFSDIPELVGPPGPDGLPGLPG-----FPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAIL 868 P L+GPPGP GLPG G F GP+G KG+ GL G PG G+ E+ P Sbjct: 200 -----PGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRP---- 250 Query: 869 TEDIPLERLMGKKGEPGMHGAPGPMGPKGPPG----HKGEFGLPGRPGRPGLNGLKGTKG 924 I +E G +G PG G PGP G +GPPG KGE G G PG+ G G G G Sbjct: 251 ---IDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENG 307 Query: 925 DPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFH- 983 PG+ PGLPG PG PG PG KG DT PG P L+ Sbjct: 308 QPGI-----PGLPGDPGYPGEPGRD-GEKG------------QKGDTGPPGPPGLVIPRP 349 Query: 984 ------GVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKG 1037 G KG G GLPG KGE+G G QGPPG P + G G GF G Sbjct: 350 GTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAA------VMGPPGPPGFPG 403 Query: 1038 EKGEKGD-------INGSFLMSGPPGLPGNPGPAGQKGETVV--------GPQGPPGAPG 1082 E+G+KGD I G + G PG PG PGP G G + GP GPPG+PG Sbjct: 404 ERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPG 463 Query: 1083 -------------------------LPGPPGF-GRPGDPGPPGPPGPPGPPAILGAAVA- 1115 + GPPG G PG PGPPG G PG G A A Sbjct: 464 DKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGAT 523 Query: 1116 -------LPGPPGPPGQPGLPGSRNLVTAFSNM 1141 +PG PG PG PG G + F M Sbjct: 524 GPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGM 556 Score = 184 bits (467), Expect = 5e-46 Identities = 151/448 (33%), Positives = 178/448 (39%), Gaps = 126/448 (28%) Query: 478 ASGVPTDGLAPLTATMAPE--RAVTSGPGDEEDLAAATTEEPLITAGGEESGSPPPDGPP 535 A G P GL T P + ++ PG+ EP GG G P P Sbjct: 1114 AKGQP--GLPGFPGTPGPPGPKGISGPPGNP-----GLPGEPGPVGGGGHPGQPGP---- 1162 Query: 536 LPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGS 595 P ++ G G GP G+KG+ G+ G P P G G +G + +G Sbjct: 1163 -------------PGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPG-LSGQKGDGG 1208 Query: 596 GLGWGSDVG----------------SGSGDLVGSE-QLLRGPPGPPGPPGLPGIPGKPGT 638 G + G G GS L GP G PGP G PG PG G Sbjct: 1209 LPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQGL 1268 Query: 639 DVFMGPPGSPGEDGPAGE---PGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGD 695 GPPG PG G GE PG PG G PG+ G G PG++G G G NG KGD Sbjct: 1269 PGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGM---KGD 1325 Query: 696 PGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPK 755 PG G+PG PG KG +G PG GP G PG GPPGP G SG + ++ Sbjct: 1326 PGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPG-------PSGQSIII---- 1374 Query: 756 LSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNF 815 KGD GP G G G + G PGP+GP G Sbjct: 1375 -------------KGDAGPPGIPGQPG--LKGLPGPQGPQG------------------- 1400 Query: 816 SDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLE 875 +P GPPG G GLPGF G G KGD GLPG PG + Sbjct: 1401 --LPGPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTR-------------------- 1438 Query: 876 RLMGKKGEPGMHGAPGPMGPKGPPGHKG 903 G+ G PGP G +GPPG G Sbjct: 1439 ---------GLDGPPGPDGLQGPPGPPG 1457 Score = 159 bits (401), Expect = 2e-38 Identities = 134/373 (35%), Positives = 155/373 (41%), Gaps = 85/373 (22%) Query: 527 GSPPPDGPP-LPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEE-LPGPPEPSGPV 584 G+P P GP + P P P G GQ GP GEKG G++ +PGP G Sbjct: 1125 GTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEP 1184 Query: 585 GPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGP 644 G GL G G G L G + G PG PGP G PG G PG GP Sbjct: 1185 GQPGFGNPGPPGLP-GLSGQKGDGGLPG----IPGNPGLPGPKGEPGFHGFPGVQGPPGP 1239 Query: 645 PGSPGE--DGPAGEPGP------------PGPEGQPGVDG---------------ATGLP 675 PGSPG +GP G PGP PGPEG PG+ G GLP Sbjct: 1240 PGSPGPALEGPKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLP 1299 Query: 676 GMKGEKGARGPNGSVGE------KGDPGNRGLPGPPGKKG------QAGP---PGVMGPP 720 G+KG++G G G+ G KGDPG G+PG PG KG AGP PG++GPP Sbjct: 1300 GLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPP 1359 Query: 721 GPPGPPGPPG-----------PGCTMGLGFEDTEGSGSTQLLNEPK----------LSRP 759 GPPG PGP G PG G + G Q L P L Sbjct: 1360 GPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGF 1419 Query: 760 TAAIGLKGEKGDRGPKGERGMDGASIVGPPG---PRGPPGHIKVLSNSLINITHGFMNFS 816 A G KG+ G G G RG+DG GP G P GPPG ++ HGF+ Sbjct: 1420 DGAGGRKGDPGLPGQPGTRGLDGPP--GPDGLQGPPGPPG--------TSSVAHGFLITR 1469 Query: 817 DIPELVGPPGPDG 829 P P G Sbjct: 1470 HSQTTDAPQCPQG 1482 Score = 136 bits (343), Expect = 1e-31 Identities = 106/293 (36%), Positives = 121/293 (41%), Gaps = 56/293 (19%) Query: 882 GEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPP------- 934 G+P A P G G G G PGL G G G PG +GPP Sbjct: 21 GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPG--PEGPPGPRGQKG 78 Query: 935 --GLPGPPGPP---GPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEK 989 G+PGPPGP GPPG + P P +P H G+P G G K Sbjct: 79 DDGIPGPPGPKGIRGPPG--------LPGFPGTP--GLPGMPGHDGAPGPQGIPGCNGTK 128 Query: 990 GSWGLPGSKGEKGDQGAQGPPG-PPLDLAYLRHFLNNLKGENGDKGFKGEKGEKG----- 1043 G G PGS G G QG GPPG P + +++L G G+ G+ G G +G Sbjct: 129 GERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPT 188 Query: 1044 DINGSFLMSGPPGL------PGNPGPAGQKGETVVGPQGPPGAPGLPGPPG--------- 1088 I G GPPGL PG PGP G G GP+G G GL GPPG Sbjct: 189 GIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQK 248 Query: 1089 -----------FGRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPG 1130 G PGD GPPGPPG GPP G G G PG+ G PG Sbjct: 249 RPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPG 301 Score = 70.1 bits (170), Expect = 1e-11 Identities = 58/177 (32%), Positives = 72/177 (40%), Gaps = 23/177 (12%) Query: 527 GSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAG-EELPGPPEPSGPVG 585 GS P+G P + P P+ + + +KG AGP G G G + LPGP P G G Sbjct: 1345 GSAGPEGEPGLIGPPGPPGLPGPSGQSII-IKGDAGPPGIPGQPGLKGLPGPQGPQGLPG 1403 Query: 586 PTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPP 645 PT G G D G +G PG PG PG G+ G PG D GPP Sbjct: 1404 PTGPPGDPGRNGLPGFDGAGGR----------KGDPGLPGQPGTRGLDGPPGPDGLQGPP 1453 Query: 646 GSPGEDGPA----------GEPGPPGPEGQPGVDGATGLPGMKGEKGARGPN-GSVG 691 G PG A P P+G V L ++G K A G + G+ G Sbjct: 1454 GPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQVYEGFSLLYVQGNKRAHGQDLGTAG 1510 >gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sapiens] Length = 1685 Score = 392 bits (1007), Expect = e-108 Identities = 277/681 (40%), Positives = 318/681 (46%), Gaps = 116/681 (17%) Query: 525 ESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSGPV 584 + G P P GPP P + VG GQ GP G G G + GPP P G Sbjct: 776 DRGFPGPPGPPGRTGLDG-----LPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIP 830 Query: 585 GPTAGAEAEGSGLGWGSDVGSGSGDLVG-----SEQLLRGPPGPPGPPGLPGIPGKPGTD 639 GP G G D G D+ G + G PGP GPPG PG+PGK G Sbjct: 831 GPIGQPGLHGIP-GEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGAS 889 Query: 640 VF---------MGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARG----- 685 F MGPPG PG G G G PG +G G+ G GLPG GEKG++G Sbjct: 890 GFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLP 949 Query: 686 -------PN--GSVGEKGDPG------------NRGLPGPPGKKGQAGPPGVMGPPGPPG 724 PN GS GEKG+PG +GLPG PG+ G +G PG+ GPPGP G Sbjct: 950 GPPGPMDPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKG 1009 Query: 725 PPGPPG-PGCTMGLGFEDTEGS----GSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERG 779 PG PG PG G + T G G + P S G G G +G KG+ G Sbjct: 1010 NPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPG 1069 Query: 780 MDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGP 839 + + G PGP+G PG N I + G +P G G GLPG PG PGP Sbjct: 1070 ISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGP 1129 Query: 840 RGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPP 899 GPKG +G PG PGL GE G G G P G+KG+PG G PGP G KG P Sbjct: 1130 PGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPP-----GEKGKPGQDGIPGPAGQKGEP 1184 Query: 900 GHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPG------------PPGPPG 947 G G FG PG PG PGL+G KG G PG+ G PGLPGP G PPGPPG Sbjct: 1185 GQPG-FGNPGPPGLPGLSGQKGDGGLPGI--PGNPGLPGPKGEPGFHGFPGVQGPPGPPG 1241 Query: 948 AVINIKGAIFPIPVRPHCK-MPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGA 1006 + P P K P PG P G+ G +G GLPG+ G KG++G Sbjct: 1242 S---------PGPALEGPKGNPGPQGPPGRP------GLPGPEGPPGLPGNGGIKGEKGN 1286 Query: 1007 QGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQ 1066 G PG P L LKG+ G G +G G G +NG M G PGLPG PG G Sbjct: 1287 PGQPGLP--------GLPGLKGDQGPPGLQGNPGRPG-LNG---MKGDPGLPGVPGFPGM 1334 Query: 1067 KGETVV----GPQGPPGAPGLPGPPGFGRP--------GDPGPPGPPGPPGPPAILG--A 1112 KG + V GP+G PG G PGPPG P GD GPPG PG PG + G Sbjct: 1335 KGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQG 1394 Query: 1113 AVALPGPPGPPGQP---GLPG 1130 LPGP GPPG P GLPG Sbjct: 1395 PQGLPGPTGPPGDPGRNGLPG 1415 Score = 382 bits (980), Expect = e-105 Identities = 271/709 (38%), Positives = 309/709 (43%), Gaps = 195/709 (27%) Query: 549 PAQREHVGMKGQAGPKGEKGDAGEE----LPGPPEPSGPVGPTAGAEAEGSGLGWGSDVG 604 P H G+ G GP+G G G++ +PGPP P G Sbjct: 53 PGLEGHPGLPGFPGPEGPPGPRGQKGDDGIPGPPGPKG---------------------- 90 Query: 605 SGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEG 664 +RGPPG PG PG PG+PG PG D GP G PG +G GE G PG G Sbjct: 91 ------------IRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKGERGFPGSPG 138 Query: 665 QPGVD---GATGLPGMKGEKGA------RGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPG 715 PG+ G G+PGMKGE G+ GP G+ G G PG +GLPGP G G GPPG Sbjct: 139 FPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPG 198 Query: 716 VMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEP-----KLSRPTAAIGLKGEKG 770 G GPPGPPG PGP MGL F+ +G Q L P ++S I ++ +KG Sbjct: 199 PPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRPIDVEFQKG 258 Query: 771 DRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPD-- 828 D+G G+RG GPPG RGPPG G P G PG D Sbjct: 259 DQGLPGDRGPP-----GPPGIRGPPGP--------PGGEKGEKGEQGEPGKRGKPGKDGE 305 Query: 829 -GLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTE-----------DIPLER 876 G PG+PG PG G G+ G G G KG+ G G PG ++ +I L Sbjct: 306 NGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPG 365 Query: 877 LMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGL 936 L G+KGE G G GP G GPPG G PG PG PG G KG +G PG+ + GPPGL Sbjct: 366 LPGEKGERGFPGIQGPPGLPGPPG-AAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGL 424 Query: 937 PGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSP---------ELITFHGVKG 987 G PG PG PG P P PH + PG P L GVKG Sbjct: 425 DGQPGAPGLPGP---------PGPAGPHIPPSDEICEPGPPGPPGSPGDKGLQGEQGVKG 475 Query: 988 EK----------------------------GSWGLPGSKGEKGDQGAQGPPGPPLDLAYL 1019 +K GS G PG KGEKG GA GP G P Sbjct: 476 DKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGATGPKGLP------ 529 Query: 1020 RHFLNNLKGENGDKGFKGEKGEKGDI---------NGSFLMSGPPGLPGNPGPAGQ---- 1066 + G G GF G KGE GDI G G PGLPG PG GQ Sbjct: 530 -----GIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTPGQDGLP 584 Query: 1067 -----KGE----TVVGPQGPPGAPGLP---------GPPGFGRP------------GDPG 1096 KGE T G +GPPG PGLP GPPGFG P G+PG Sbjct: 585 GLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPG 644 Query: 1097 PPGPPGP----------PGPPAILG-----AAVALPGPPGPPGQPGLPG 1130 PG PGP PG P + G V LPG PG PGQPGLPG Sbjct: 645 QPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPG 693 Score = 374 bits (960), Expect = e-103 Identities = 287/719 (39%), Positives = 325/719 (45%), Gaps = 167/719 (23%) Query: 527 GSPPPDG-PPLPLPTVAPERWITPAQREHVGMKGQAGPKG---EKGDAGEELPGPPEPSG 582 G P P G P +P P AP TP + +G++G GP G KG+ G LPGPP P G Sbjct: 710 GPPGPKGFPGIPGPPGAPG---TPGR---IGLEGPPGPPGFPGPKGEPGFALPGPPGPPG 763 Query: 583 PVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFM 642 G +G RG PGPPGPPG G+ G PG + Sbjct: 764 LPGFKGALGPKGD----------------------RGFPGPPGPPGRTGLDGLPGPKGDV 801 Query: 643 GPPGSPGEDGPAGEPG-----PPGPEGQPGVDGATGLPGMKGEKGARGPNG-----SVGE 692 GP G PG GP G PG PPGP G PG G GL G+ GEKG GP G GE Sbjct: 802 GPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGE 861 Query: 693 KGDPGNRGLPGP---------PGKKGQAGPPG------VMGPPGPPGPPGPPGPGCTMGL 737 +G PG G PGP PGK G +G PG +MGPPGPPGP G PG GL Sbjct: 862 RGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGVPGL 921 Query: 738 GFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGP-----------KGERGMDGASIV 786 G L +P L PT G KGE G GP KGE+G G + Sbjct: 922 -------KGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPMDPNLLGSKGEKGEPG--LP 972 Query: 787 GPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPG----------- 835 G PG GP G+ + + G S P L GPPGP G PGLPG Sbjct: 973 GIPGVSGPKGYQGLPGDP------GQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLK 1026 Query: 836 -------FPGPRG------PKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKG 882 FPGP+G P G G PG PGL G++G+KG+PG I L L G KG Sbjct: 1027 GTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGI---SSIGLPGLPGPKG 1083 Query: 883 EPGMHGAPGPMGPKGPPGHKGEFGLPGRPG---RPGLNGLKGTKGDPGVI-MQGPPG--- 935 EPG+ G PG G KG G G GLPG PG +PGL G GT G PG + GPPG Sbjct: 1084 EPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPG 1143 Query: 936 LPGPPGP---------PGPPG--AVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHG 984 LPG PGP PGPPG G P + P +PG P L G Sbjct: 1144 LPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQP-GFGNPGPPGLPGLSG 1202 Query: 985 VKGE------KGSWGLPGSKGEKGDQG---AQGPPGPPLDLAYLRHFLNNLKGENGDKGF 1035 KG+ G+ GLPG KGE G G QGPPGPP L KG G +G Sbjct: 1203 QKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPA---LEGPKGNPGPQGP 1259 Query: 1036 KGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGET----------VVGPQGPPGAPGLPG 1085 G G G GPPGLPGN G G+KG + G QGPPG G PG Sbjct: 1260 PGRPGLPGP-------EGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPG 1312 Query: 1086 PPGF----GRPGDPGPPGPPGPPGPPAILGAA-----VALPGPPGPPGQPGLPGSRNLV 1135 PG G PG PG PG PG GP + G+A L GPPGPPG PG G ++ Sbjct: 1313 RPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIII 1371 Score = 374 bits (959), Expect = e-103 Identities = 279/701 (39%), Positives = 310/701 (44%), Gaps = 126/701 (17%) Query: 527 GSPPPDGPP----LPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEP-- 580 G+P GPP LP PT P P +G G G G KG+ G GP Sbjct: 171 GNPGYPGPPGIQGLPGPTGIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKG 230 Query: 581 ----SGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKP 636 GP GP + + DV GD Q L G GPPGPPG+ G PG P Sbjct: 231 EQGLQGPPGPPGQISEQKRPI----DVEFQKGD-----QGLPGDRGPPGPPGIRGPPGPP 281 Query: 637 GTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDP 696 G + G G GE G G+PG G GQPG+ G G PG GE G G G G+ G P Sbjct: 282 GGE--KGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPP 339 Query: 697 -------------------GNRGLPGPPGKKGQAGPPGVMGPPGPPGPP-----GPPG-P 731 GN GLPG PG+KG+ G PG+ GPPG PGPP GPPG P Sbjct: 340 GPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPP 399 Query: 732 GCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGP 791 G G + EG + P L A GL G G GP D GPPGP Sbjct: 400 GFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPS-DEICEPGPPGP 458 Query: 792 RGPPGHIKVLSNSLINITHGFMNFSDI-PELVGPPGPDGLPGLP------GFPGPR---- 840 G PG + + G F+ I + GPPG GLPGLP GFPG + Sbjct: 459 PGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKG 518 Query: 841 -----GPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGE------------ 883 GPKG G+PG PG G G KGEPG ILT + G KGE Sbjct: 519 QAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILT----FPGMKGDKGELGSPGAPGLPGL 574 Query: 884 ---PGMHGAPGPMGPKGPPG---HKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGP---- 933 PG G PG GPKG PG KGE G PG PG PGL G G G PG GP Sbjct: 575 PGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEK 634 Query: 934 --------PGLPGPPGPPGPPGAVINIKGAIFPIPVRP----HCKMPVDTAHPGSPELIT 981 PG PG PGP G PG I G +P P +P D PG P L Sbjct: 635 GIQGVAGNPGQPGIPGPKGDPGQTITQPGKP-GLPGNPGRDGDVGLPGDPGLPGQPGLPG 693 Query: 982 FHGVKGEKG--SWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEK 1039 G KGE G GLPG G KG G GPPG P + L+G G GF G K Sbjct: 694 IPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRI-----GLEGPPGPPGFPGPK 748 Query: 1040 GEKGDINGSFLMSGPPGLPGNP------GPAGQKGETVVGPQGPPGAPGLPGPPGFGRPG 1093 GE G F + GPPG PG P GP G +G GP GPPG GL G P G G Sbjct: 749 GEPG-----FALPGPPGPPGLPGFKGALGPKGDRG--FPGPPGPPGRTGLDGLP--GPKG 799 Query: 1094 DPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNL 1134 D GP G PGP GPP + G + + GPPGPPG PG G L Sbjct: 800 DVGPNGQPGPMGPPGLPG--IGVQGPPGPPGIPGPIGQPGL 838 Score = 364 bits (935), Expect = e-100 Identities = 299/837 (35%), Positives = 356/837 (42%), Gaps = 159/837 (18%) Query: 384 GPTLSMSTENPEEGVTPGPDNEERLAATAAGEAEALASMPGEVEASGVAPGELDLSMSAQ 443 GP E E+G P + + +PG+ G PG Sbjct: 276 GPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPG-EPGR------DG 328 Query: 444 SLGEEATVGPSSEDSLTTAAAATEVSLSTFEDEEASGVPTD-------GLAPLTATMAPE 496 G++ GP L T +++ + G+P + G+ P Sbjct: 329 EKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPP 388 Query: 497 RAVTSGP-------------GDEEDLAAATTEEPLITAGGEESGSPPPDGPPLPL-PTVA 542 A GP GDE + P + + G+P GPP P P + Sbjct: 389 GAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDG---QPGAPGLPGPPGPAGPHIP 445 Query: 543 PERWIT-------PAQREHVGMKGQAGPKGEKGDA-----GEELPGPPEPSGPVGPTAGA 590 P I P G++G+ G KG+KGD G + GPP G G Sbjct: 446 PSDEICEPGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPG----LPGL 501 Query: 591 EAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGE 650 LG+ G + L G PG PG PG PG G+PG + PG G+ Sbjct: 502 PGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTF--PGMKGD 559 Query: 651 DGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQ 710 G G PG PG G PG G GLPG+ G KG G GE+G PGN GLPG PG G Sbjct: 560 KGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGP 619 Query: 711 AGPPGVMGPPGP------------PGPPGPPGPGCTMGL--------GFEDTEG-SGSTQ 749 GPPG GPPGP PG PG PGP G G G G Sbjct: 620 MGPPG-FGPPGPVGEKGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVG 678 Query: 750 LLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINIT 809 L +P L G G G G KGE G+ G + GPPGP+G PG I Sbjct: 679 LPGDPGLP------GQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPG---------IPGP 723 Query: 810 HGFMNFSDIPELVGPPGPDGLPGLPGFPGPR--GPKGDTGLPGFPGLKGEQGEKGEPGAI 867 G L GPPGP G PG G PG GP G GLPGF G G +G++G PG Sbjct: 724 PGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPGPP 783 Query: 868 LTED-IPLERLMGKKGEPGMHGAPGPMGPKGPPG-----HKGEFGLPGRPGRPGLNGLKG 921 L+ L G KG+ G +G PGPMGP G PG G G+PG G+PGL+G+ G Sbjct: 784 GPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPG 843 Query: 922 TKGDPGVIMQGPPGL--PGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPEL 979 KGDPG PPGL PGPPG G PG I GA P P+ P PGSP Sbjct: 844 EKGDPG-----PPGLDVPGPPGERGSPG----IPGA--PGPIGP----------PGSP-- 880 Query: 980 ITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENG---DKGFK 1036 G+ G+ G+ G PG+KGE G G GPPGP L + R + LKG++G G Sbjct: 881 ----GLPGKAGASGFPGTKGEMGMMGPPGPPGP-LGIPG-RSGVPGLKGDDGLQGQPGLP 934 Query: 1037 GEKGEKGDINGSFLMSGPPGLPGNPGPA-----GQKGETVVGPQGPPGAPGLPGPPGF-G 1090 G GEKG G PGLPG PGP G KGE G G PG PG+ GP G+ G Sbjct: 935 GPTGEKGS-------KGEPGLPGPPGPMDPNLLGSKGEK--GEPGLPGIPGVSGPKGYQG 985 Query: 1091 RPGDPGPPGPPGPPGPPAILGAAVALPGPPGP------PGQPGLPGSRNLVTAFSNM 1141 PGDPG PG G PG LPGPPGP PGQPGL G L +M Sbjct: 986 LPGDPGQPGLSGQPG----------LPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDM 1032 Score = 362 bits (930), Expect = 1e-99 Identities = 263/653 (40%), Positives = 305/653 (46%), Gaps = 155/653 (23%) Query: 525 ESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAG---PKGEKGDAGEELPGPPEPS 581 E G P GPP PL P R P + G++GQ G P GEKG GE PG P P Sbjct: 897 EMGMMGPPGPPGPLGI--PGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGE--PGLPGPP 952 Query: 582 GPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVF 641 GP+ P L G G G PGLPGIPG G + Sbjct: 953 GPMDPN-----------------------------LLGSKGEKGEPGLPGIPGVSGPKGY 983 Query: 642 MGPPGSPGEDGPAGE---PGPPGPEGQPGVDGATGL---PGMKGE------KGARGPNGS 689 G PG PG+ G +G+ PGPPGP+G PG+ G GL PG+KG G +G G Sbjct: 984 QGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGPQGVEGP 1043 Query: 690 VGEKGDPGNRGLPGPPGKKGQAGPPGV--MGPPGPPGPPGPPG-PGCTMGLGFEDTEGSG 746 G G PG G PG PG+KG G PG+ +G PG PGP G PG PG G + + G Sbjct: 1044 PGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDP 1103 Query: 747 STQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDG-ASIVGPPGPR---GPPGHIKVLS 802 GL G G G KG+ G+ G GPPGP+ GPPG+ Sbjct: 1104 -----------------GLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGN----- 1141 Query: 803 NSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKG 862 P L G PGP G G PG PGP G KG G G PG G++GE G Sbjct: 1142 ----------------PGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPG 1185 Query: 863 EPGAILTEDIPLERLMGKKGE---PGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNG- 918 +PG L L G+KG+ PG+ G PG GPKG PG G G+ G PG PG G Sbjct: 1186 QPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGP 1245 Query: 919 -LKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVIN--IKGAIFPIPVRPHCKMPVDTAHPG 975 L+G KG+PG QGPPG PG PGP GPPG N IKG + +PG Sbjct: 1246 ALEGPKGNPG--PQGPPGRPGLPGPEGPPGLPGNGGIKG---------------EKGNPG 1288 Query: 976 SPELITFHGVKGEKGSWGL------PGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGE 1029 P L G+KG++G GL PG G KGD G G PG P +KG Sbjct: 1289 QPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFP-----------GMKGP 1337 Query: 1030 NGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQ----KGETVVGPQGPPGAPGLPG 1085 +G G G +GE G + GPPG PG PGP+GQ KG+ GP G PG PGL G Sbjct: 1338 SGVPGSAGPEGEPG-------LIGPPGPPGLPGPSGQSIIIKGD--AGPPGIPGQPGLKG 1388 Query: 1086 PPG----FGRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNL 1134 PG G PG GPPG PG G P GA G G PG PG PG+R L Sbjct: 1389 LPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAG----GRKGDPGLPGQPGTRGL 1437 Score = 357 bits (915), Expect = 6e-98 Identities = 277/752 (36%), Positives = 327/752 (43%), Gaps = 175/752 (23%) Query: 525 ESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSGPV 584 E G GPP P ++ Q+ + ++ Q G +G GD G PGPP GP Sbjct: 228 EKGEQGLQGPPGPPGQISE-------QKRPIDVEFQKGDQGLPGDRGP--PGPPGIRGPP 278 Query: 585 GPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGP 644 GP G + E G G D + + G PG PG PG PG G+ G GP Sbjct: 279 GPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPGRDGEKGQKGDTGP 338 Query: 645 PGSPG-------------EDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGAR-----GP 686 PG PG E G G PG PG +G+ G G G PG+ G GA GP Sbjct: 339 PGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGP 398 Query: 687 NGSVGEKGDPGNRG-----LPGPPGKKGQAGPPGVMGPPGP-------------PGPPGP 728 G GE+G G+ G +PGPPG GQ G PG+ GPPGP PGPPGP Sbjct: 399 PGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGP 458 Query: 729 PGPGCTMGL----GFEDTEG-----------SGSTQLLNEPKLSRPTAAIGLKGEKGDRG 773 PG GL G + +G SG P L P ++G G+KG++G Sbjct: 459 PGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKG 518 Query: 774 ------PKGERGMDGA-SIVGPPGPRGPPGHIKVLSNSLINITH-GFMNFSDIPELVGPP 825 PKG G+ GA G PG +G PG I + G +P L G P Sbjct: 519 QAGATGPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGMKGDKGELGSPGAPGLPGLPGTP 578 Query: 826 GPDGLPGLPG---------FPGPRGPKGDTGLPGFPGLKGEQGEKG--EPGAILTEDIPL 874 G DGLPGLPG F G RGP G+ GLPG PG G G G PG + + I Sbjct: 579 GQDGLPGLPGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGI-- 636 Query: 875 ERLMGKKGEPGMHGAPGPMGPKGP-------------PGHKGEFGLPGRPG---RPGLNG 918 G G PG G PGP G G PG G+ GLPG PG +PGL G Sbjct: 637 ---QGVAGNPGQPGIPGPKGDPGQTITQPGKPGLPGNPGRDGDVGLPGDPGLPGQPGLPG 693 Query: 919 LKGTKGDPGVIMQGPPGLPGP---PGPPGPPGAV-----INIKGAIFPIPVRPHCKMPVD 970 + G+KG+PG+ G PG PGP PG PGPPGA I ++G P P P K Sbjct: 694 IPGSKGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGP-PGFPGPKGEPG 752 Query: 971 TAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGEN 1030 A PG P G G G G+ G KGD+G GPPGPP R L+ L G Sbjct: 753 FALPGPP---------GPPGLPGFKGALGPKGDRGFPGPPGPPG-----RTGLDGLPGPK 798 Query: 1031 GDKGFKGEKGEKGDINGSFL-MSGPPGLPGNPGPAGQKG-ETVVGPQGPPGAPGL--PGP 1086 GD G G+ G G + + GPPG PG PGP GQ G + G +G PG PGL PGP Sbjct: 799 GDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIPGEKGDPGPPGLDVPGP 858 Query: 1087 PGF-GRPGDPGPPGPPGPPGPPAILGAAVAL----------------------------- 1116 PG G PG PG PGP GPPG P + G A A Sbjct: 859 PGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMGPPGPPGPLGIPGRSGV 918 Query: 1117 ------------PGPPGP------PGQPGLPG 1130 PG PGP G+PGLPG Sbjct: 919 PGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPG 950 Score = 318 bits (815), Expect = 2e-86 Identities = 238/633 (37%), Positives = 273/633 (43%), Gaps = 167/633 (26%) Query: 577 PPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKP 636 P E + G + G++ + SG + E+ RG PG G PGLPG PG Sbjct: 23 PAEAAACYGCSPGSKCDCSG--------------IKGEKGERGFPGLEGHPGLPGFPGPE 68 Query: 637 GTDVFMGPPGSPGEDGPAGEPGPPG---PEGQPGVDGATGLPGMKGEKGARGPNGSVGEK 693 G GP G G+DG G PGP G P G PG G GLPGM G GA GP G G Sbjct: 69 GPP---GPRGQKGDDGIPGPPGPKGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCN 125 Query: 694 GDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNE 753 G G RG PG PG PG+ GPPGPPG PG G E Sbjct: 126 GTKGERGFPGSPGF------PGLQGPPGPPGIPGMKG----------------------E 157 Query: 754 PKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFM 813 P ++ G KG G GP G +G+ G + G PGP GPPG Sbjct: 158 PGSIIMSSLPGPKGNPGYPGPPGIQGLPGPT--GIPGPIGPPGP---------------- 199 Query: 814 NFSDIPELVGPPGPDGLPGLPG-----FPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAIL 868 P L+GPPGP GLPG G F GP+G KG+ GL G PG G+ E+ P Sbjct: 200 -----PGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQKRP---- 250 Query: 869 TEDIPLERLMGKKGEPGMHGAPGPMGPKGPPG----HKGEFGLPGRPGRPGLNGLKGTKG 924 I +E G +G PG G PGP G +GPPG KGE G G PG+ G G G G Sbjct: 251 ---IDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENG 307 Query: 925 DPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFH- 983 PG+ PGLPG PG PG PG KG DT PG P L+ Sbjct: 308 QPGI-----PGLPGDPGYPGEPGRD-GEKG------------QKGDTGPPGPPGLVIPRP 349 Query: 984 ------GVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKG 1037 G KG G GLPG KGE+G G QGPPG P + G G GF G Sbjct: 350 GTGITIGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAA------VMGPPGPPGFPG 403 Query: 1038 EKGEKGD-------INGSFLMSGPPGLPGNPGPAGQKGETVV--------GPQGPPGAPG 1082 E+G+KGD I G + G PG PG PGP G G + GP GPPG+PG Sbjct: 404 ERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIPPSDEICEPGPPGPPGSPG 463 Query: 1083 -------------------------LPGPPGF-GRPGDPGPPGPPGPPGPPAILGAAVA- 1115 + GPPG G PG PGPPG G PG G A A Sbjct: 464 DKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGFPGQKGEKGQAGAT 523 Query: 1116 -------LPGPPGPPGQPGLPGSRNLVTAFSNM 1141 +PG PG PG PG G + F M Sbjct: 524 GPKGLPGIPGAPGAPGFPGSKGEPGDILTFPGM 556 Score = 238 bits (606), Expect = 4e-62 Identities = 182/467 (38%), Positives = 207/467 (44%), Gaps = 90/467 (19%) Query: 525 ESGSPPP---DGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPS 581 + G P P +GPP P P Q G+ GQ G KG+ G + LPG P P Sbjct: 1031 DMGFPGPQGVEGPPGPSGV--------PGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPK 1082 Query: 582 GPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVF 641 G G G GS G L G+ G G PG PG PG PG PG Sbjct: 1083 GEPGLPGYPGNPGIK---GSVGDPGLPGLPGTP----GAKGQPGLPGFPGTPGPPGPKGI 1135 Query: 642 MGPPGSPG---EDGPAG------EPGPPGPEGQPGVDGATGLPGMKGEKGARGPN----- 687 GPPG+PG E GP G +PGPPG +G+PG DG G G KGE G G Sbjct: 1136 SGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPP 1195 Query: 688 ---GSVGEKGD------PGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGP--------PG 730 G G+KGD PGN GLPGP G+ G G PGV GPPGPPG PGP PG Sbjct: 1196 GLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPG 1255 Query: 731 PGCTMGL-GFEDTEGS----GSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGA-- 783 P G G EG G+ + E GL G KGD+GP G +G G Sbjct: 1256 PQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPG 1315 Query: 784 --SIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPG----FP 837 + G PG G PG + S + G P L+GPPGP GLPG G Sbjct: 1316 LNGMKGDPGLPGVPGFPGMKGPSGVP---GSAGPEGEPGLIGPPGPPGLPGPSGQSIIIK 1372 Query: 838 GPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKG 897 G GP G G PG GL G QG +G PG P G+ G PG GA Sbjct: 1373 GDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDP-----GRNGLPGFDGA-------- 1419 Query: 898 PPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPG 944 G KG+ GLPG+PG GL+G GP GL GPPGPPG Sbjct: 1420 -GGRKGDPGLPGQPGTRGLDG-----------PPGPDGLQGPPGPPG 1454 Score = 160 bits (405), Expect = 8e-39 Identities = 129/365 (35%), Positives = 151/365 (41%), Gaps = 72/365 (19%) Query: 527 GSPPPDGPP-LPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEE-LPGPPEPSGPV 584 G+P P GP + P P P G GQ GP GEKG G++ +PGP G Sbjct: 1125 GTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEP 1184 Query: 585 GPTAGAEAEGSGL-GWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTD---- 639 G GL G G G + L GP G PG G PG+ G PG Sbjct: 1185 GQPGFGNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPG 1244 Query: 640 -VFMGPPGSPGEDGPAGEPGPPGPEGQPGVDG---------------ATGLPGMKGEKGA 683 GP G+PG GP G PG PGPEG PG+ G GLPG+KG++G Sbjct: 1245 PALEGPKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGP 1304 Query: 684 RGPNGSVGE------KGDPGNRGLPGPPGKKG------QAGP---PGVMGPPGPPGPPGP 728 G G+ G KGDPG G+PG PG KG AGP PG++GPPGPPG PGP Sbjct: 1305 PGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGP 1364 Query: 729 PG-----------PGCTMGLGFEDTEGSGSTQLLNEPK----------LSRPTAAIGLKG 767 G PG G + G Q L P L A G KG Sbjct: 1365 SGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKG 1424 Query: 768 EKGDRGPKGERGMDGASIVGPPG---PRGPPGHIKVLSNSLINITHGFMNFSDIPELVGP 824 + G G G RG+DG GP G P GPPG ++ HGF+ P Sbjct: 1425 DPGLPGQPGTRGLDGPP--GPDGLQGPPGPPG--------TSSVAHGFLITRHSQTTDAP 1474 Query: 825 PGPDG 829 P G Sbjct: 1475 QCPQG 1479 Score = 136 bits (343), Expect = 1e-31 Identities = 106/293 (36%), Positives = 121/293 (41%), Gaps = 56/293 (19%) Query: 882 GEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPP------- 934 G+P A P G G G G PGL G G G PG +GPP Sbjct: 21 GQPAEAAACYGCSPGSKCDCSGIKGEKGERGFPGLEGHPGLPGFPG--PEGPPGPRGQKG 78 Query: 935 --GLPGPPGPP---GPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEK 989 G+PGPPGP GPPG + P P +P H G+P G G K Sbjct: 79 DDGIPGPPGPKGIRGPPG--------LPGFPGTP--GLPGMPGHDGAPGPQGIPGCNGTK 128 Query: 990 GSWGLPGSKGEKGDQGAQGPPG-PPLDLAYLRHFLNNLKGENGDKGFKGEKGEKG----- 1043 G G PGS G G QG GPPG P + +++L G G+ G+ G G +G Sbjct: 129 GERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPT 188 Query: 1044 DINGSFLMSGPPGL------PGNPGPAGQKGETVVGPQGPPGAPGLPGPPG--------- 1088 I G GPPGL PG PGP G G GP+G G GL GPPG Sbjct: 189 GIPGPIGPPGPPGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGPPGPPGQISEQK 248 Query: 1089 -----------FGRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPG 1130 G PGD GPPGPPG GPP G G G PG+ G PG Sbjct: 249 RPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPG 301 Score = 70.1 bits (170), Expect = 1e-11 Identities = 58/177 (32%), Positives = 72/177 (40%), Gaps = 23/177 (12%) Query: 527 GSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAG-EELPGPPEPSGPVG 585 GS P+G P + P P+ + + +KG AGP G G G + LPGP P G G Sbjct: 1342 GSAGPEGEPGLIGPPGPPGLPGPSGQSII-IKGDAGPPGIPGQPGLKGLPGPQGPQGLPG 1400 Query: 586 PTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPP 645 PT G G D G +G PG PG PG G+ G PG D GPP Sbjct: 1401 PTGPPGDPGRNGLPGFDGAGGR----------KGDPGLPGQPGTRGLDGPPGPDGLQGPP 1450 Query: 646 GSPGEDGPA----------GEPGPPGPEGQPGVDGATGLPGMKGEKGARGPN-GSVG 691 G PG A P P+G V L ++G K A G + G+ G Sbjct: 1451 GPPGTSSVAHGFLITRHSQTTDAPQCPQGTLQVYEGFSLLYVQGNKRAHGQDLGTAG 1507 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 376 bits (965), Expect = e-104 Identities = 256/643 (39%), Positives = 295/643 (45%), Gaps = 89/643 (13%) Query: 527 GSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEE-LPGPPEPSGPVG 585 G P GP P P R G KG GP+G G+ G PGPP P GP G Sbjct: 117 GPKGPPGPQGPAGEQGPR-----GDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPG 171 Query: 586 PTAGAEAEGSGLGWGSDVGSGSGDLVGSEQL--LRGPPGPPGPPGLPGIPGKPGTDVFMG 643 P G G + + + G + G QL ++GP GP GP G PG G PG F G Sbjct: 172 PP------GLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQG 225 Query: 644 PPGSPGE---DGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDP---- 696 PG PGE GP G GPPGP G+PG DG G PG GE+G GP G+ G G P Sbjct: 226 NPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPG 285 Query: 697 --GNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFE-----DTEGSGSTQ 749 G+RG PG G KG+AG PGV G G PG G PGP GL E +G+ Sbjct: 286 VKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARG 345 Query: 750 LLNEPKLSRPTAAI---------GLKGEKGDRGPKGERGMDGA-SIVGPPGPRGPPGHIK 799 +P + P + G G KG+ GP G RG +GA G PG G PG Sbjct: 346 NDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAG 405 Query: 800 VLSNSLINITHGFMNFSDIPELVGP---PGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKG 856 N + G + P + G PGP G PG G GP GPKG TG PG G KG Sbjct: 406 ASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKG 465 Query: 857 EQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGL 916 EQG KGEPG + P G++G+ G G PG +GP GPP GE G PG G PG Sbjct: 466 EQGPKGEPGPAGPQGAP--GPAGEEGKRGARGEPGGVGPIGPP---GERGAPGNRGFPGQ 520 Query: 917 NGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGS 976 +GL G KG PG +GP GL GP G G PG RP PG Sbjct: 521 DGLAGPKGAPG--ERGPSGLAGPKGANGDPG--------------RP--------GEPGL 556 Query: 977 PELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFK 1036 P G G+ G G G G G+ G GPPGP +G+ G GF Sbjct: 557 PGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGP-----------QGARGQPGVMGFP 605 Query: 1037 GEKGEKGDIN--GSFLMSGPPGLPGNPGPAGQKGET----VVGPQGPPGAPGLPGPPGF- 1089 G KG G+ G + G PGL G PG G+ G GP G G G PGP GF Sbjct: 606 GPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQ 665 Query: 1090 GRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSR 1132 G PG PGPPG G PG + G A A PG GP G+ G PG R Sbjct: 666 GLPGPPGPPGEGGKPGDQGVPGEAGA-PGLVGPRGERGFPGER 707 Score = 366 bits (939), Expect = e-101 Identities = 261/690 (37%), Positives = 306/690 (44%), Gaps = 103/690 (14%) Query: 527 GSPPPDGPPLPLPTVAPERWI-------TPAQREHVGMKGQAGPKGEKGDAGEE-LPGPP 578 G P GPP P P+ + P +G +G GP G+ GD GE PG Sbjct: 204 GPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKA 263 Query: 579 EPSGPVGP--------TAGAEAEGSGLGW-GSDVGSGSGDLVGSEQLLRGP-----PGPP 624 GP GP T G G+ G D G G + P PGP Sbjct: 264 GERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPM 323 Query: 625 GPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGAR 684 GP GLPG G+ G G G+ G+ GPAG PGP GP G PG GA G G G GAR Sbjct: 324 GPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGAR 383 Query: 685 GPNGSVGEKGDPGNRGLPGP------------PGKKGQAGPPGVMGPPGPPGPPGPPGP- 731 GP G+ G +G+PG G PGP PG KG AG PG+ G PG PGP GPPGP Sbjct: 384 GPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQ 443 Query: 732 GCTMGLGFEDTEG-------SGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGAS 784 G T LG + G G EP + P A G GE+G RG +GE G G Sbjct: 444 GATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPG--GVG 501 Query: 785 IVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKG 844 +GPPG RG PG+ + G L GP G +G PG PG PG G +G Sbjct: 502 PIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARG 561 Query: 845 DTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGE 904 TG PG G +G+ G G PG P + G +G+PG+ G PGP G G PG GE Sbjct: 562 LTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQ--GARGQPGVMGFPGPKGANGEPGKAGE 619 Query: 905 FGLPGRP---GRPGLNGLKGTKGDPGVI----------MQGPPGLPGPPGPPGPPG---- 947 GLPG P G PG +G G G PG GP G G PGPPGPPG Sbjct: 620 KGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGK 679 Query: 948 ----AVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGD 1003 V GA + R P + PG+ L G+ G G+ G G+ G G Sbjct: 680 PGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGP 739 Query: 1004 QGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDI-----------NGSFLMS 1052 GAQGPPG L + GE G G G KG++GD+ +G ++ Sbjct: 740 PGAQGPPG-----------LQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLT 788 Query: 1053 GPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPG-FGRPGDPGPPGPPGPPGPPAILG 1111 GP G PG G G+KGE VGP GP G+ G G PG G G PGP G GPPG G Sbjct: 789 GPIGPPGPAGANGEKGE--VGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPG 846 Query: 1112 AA-----------VALPGPPGPPGQPGLPG 1130 A PGP GP G PG G Sbjct: 847 AKGEQGEAGQKGDAGAPGPQGPSGAPGPQG 876 Score = 358 bits (918), Expect = 3e-98 Identities = 330/1014 (32%), Positives = 398/1014 (39%), Gaps = 164/1014 (16%) Query: 205 GNAGATGLERFTGSLQQLTVHPDPRTPEELCDPEESSASGETSGLQEADGVAEILEAVTY 264 G AGA G++ +GS + P P P L + +G + DG Sbjct: 300 GEAGAPGVKGESGSPGE-NGSPGPMGPRGLPGERGRTGPAGAAGARGNDG---------- 348 Query: 265 TQASPKEAKVEPINTPPTPSSPFEDMELSGEPVPEGTLETTNMSIIQHSSPKQGS-GEIL 323 Q P PP P P G P +G T + QG GE Sbjct: 349 -QPGPAG--------PPGPVGPAGGPGFPGAPGAKGEAGPTGA---RGPEGAQGPRGEPG 396 Query: 324 NDTLEGVHSVDGDPITDSGSGAGAFLDIAEEKNLAATAAGLAEVPISTAGEAEASSVPTG 383 G G+P TD GA +A A G+A P Sbjct: 397 TPGSPGPAGASGNPGTDGIPGAKG----------SAGAPGIAGAPGFPGPRGPPGPQGAT 446 Query: 384 GPTLSMSTENPEEGVT-----------PGPDNEERLAATAAGEAEALA-SMPGEVEASGV 431 GP L + E G+ PGP + A E + A PG V G Sbjct: 447 GP-LGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIG- 504 Query: 432 APGELDLSMSAQSLGEEATVGPSSEDSLTTAAAATEVSLSTFEDEEASGVPTDGLAPLTA 491 PGE + G++ GP A E S + G D P Sbjct: 505 PPGERGAPGNRGFPGQDGLAGPKG--------APGERGPSGLAGPK--GANGDPGRPGEP 554 Query: 492 TMAPERAVTSGPGDEEDLAAATTEEPLITAGGEESGSPPPDGPPLPLPTVAPERWITPAQ 551 + R +T PGD P G SG+P DG P P P Q Sbjct: 555 GLPGARGLTGRPGDAG---------PQGKVG--PSGAPGEDGRPGP-----PGPQGARGQ 598 Query: 552 REHVGMKGQAGPKGEKGDAGEE-LPGPPEPSGPVGPTA--GAEAEGSGLGWGSDVGSGSG 608 +G G G GE G AGE+ LPG P G G GA G + G Sbjct: 599 PGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGA 658 Query: 609 DLVGSEQLLRGPPGPPGPPGLPG---IPGKPGTDVFMGP--------------------- 644 Q L GPPGPPG G PG +PG+ G +GP Sbjct: 659 PGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGP 718 Query: 645 ---PGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGL 701 PG+PG DGP G GP GP PG G GL GM GE+GA G G G++GD G +G Sbjct: 719 RGLPGTPGTDGPKGASGPAGP---PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGP 775 Query: 702 PGPPGKKGQAGPPGVMGPPGPPG---------PPGPPGPGCTMGLGFE--DTEGSGSTQL 750 G PGK G G G +GPPGP G PPGP G G E +T G Sbjct: 776 EGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGF 835 Query: 751 LNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITH 810 P A G +GE G +G G G G S G PGP+GP G Sbjct: 836 AGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPS--GAPGPQGPTGVTGPKGARGAQGPP 893 Query: 811 GFMNFSDIPELVGPPGPDGLPGLPGFPGP------RGPKGDTGLPGFPGLKGEQGEKGEP 864 G F VGPPG +G PG PG PGP +G +GD+G PG G G QG G P Sbjct: 894 GATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPP 953 Query: 865 GAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKG 924 G G+ G+ G GA GP GP+G G +G GLPG+ G G GL G G Sbjct: 954 GE-----------KGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSG 1002 Query: 925 DPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHG 984 +PG QG PG G GPPGP G G P P PG G Sbjct: 1003 EPG--KQGAPGASGDRGPPGPVGP----PGLTGPAGEPGREGSPGADGPPGRDGAAGVKG 1056 Query: 985 VKGEKGSWGLPGS---------------KGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGE 1029 +GE G+ G PG+ +G++G+ GAQGP GP + +G Sbjct: 1057 DRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAG--ARGIQGPQGP 1114 Query: 1030 NGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGET-VVGPQGPPGAPGLPGPPG 1088 GDKG GE GE+G + G +G GLPG PGP+G +G + GP GP G PG GP G Sbjct: 1115 RGDKGEAGEPGERG-LKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSG 1173 Query: 1089 F-GRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNLVTAFSNM 1141 G G PGP GPPGP G G A PG PGPPG PG PG ++AF+ + Sbjct: 1174 KDGANGIPGPIGPPGPRGRSGETGPA-GPPGNPGPPGPPGPPGPGIDMSAFAGL 1226 Score = 309 bits (791), Expect = 1e-83 Identities = 217/551 (39%), Positives = 242/551 (43%), Gaps = 124/551 (22%) Query: 622 GPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEK 681 G PGP G G PG +GP G PG GPAGE GP G G KGEK Sbjct: 98 GQPGPKGQKGEPGD--IKDIVGPKGPPGPQGPAGEQGPRGDRGD------------KGEK 143 Query: 682 GARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGV------------------------M 717 GA GP G GE G PGN PGPPG G GPPG+ Sbjct: 144 GAPGPRGRDGEPGTPGN---PGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQ 200 Query: 718 GPPGPPGPPGPPGPGCTMG-LGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKG 776 GP GP GP GPPGP G GF+ G EP +S P G G G G G Sbjct: 201 GPMGPMGPRGPPGPAGAPGPQGFQGNPGEP-----GEPGVSGPMGPRGPPGPPGKPGDDG 255 Query: 777 ERGMDG-ASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPG 835 E G G A GPPGP+G G G PG G+ G G Sbjct: 256 EAGKPGKAGERGPPGPQGARG------------------------FPGTPGLPGVKGHRG 291 Query: 836 FPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLER----LMGKKGEPGMHGAPG 891 +PG G KG+ G PG G G GE G PG + +P ER G G G G PG Sbjct: 292 YPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPG 351 Query: 892 PMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVIN 951 P GP GP G G G PG PG G G G +G G QGP G PG PG PGP GA Sbjct: 352 PAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGA--QGPRGEPGTPGSPGPAGA--- 406 Query: 952 IKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPG 1011 + +PG+ G+ G KGS G PG G G G +GPPG Sbjct: 407 -------------------SGNPGT------DGIPGAKGSAGAPGIAGAPGFPGPRGPPG 441 Query: 1012 PPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGET- 1070 P L GE G GFKGE+G KG+ GP G G PGPAG++G+ Sbjct: 442 PQGATGPLGP--KGQTGEPGIAGFKGEQGPKGE-------PGPAGPQGAPGPAGEEGKRG 492 Query: 1071 ------VVGPQGPPGAPGLPGPPGF-GRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPP 1123 VGP GPPG G PG GF G+ G GP G PG GP + G A G PG P Sbjct: 493 ARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGA-NGDPGRP 551 Query: 1124 GQPGLPGSRNL 1134 G+PGLPG+R L Sbjct: 552 GEPGLPGARGL 562 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 376 bits (965), Expect = e-104 Identities = 256/643 (39%), Positives = 295/643 (45%), Gaps = 89/643 (13%) Query: 527 GSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEE-LPGPPEPSGPVG 585 G P GP P P R G KG GP+G G+ G PGPP P GP G Sbjct: 48 GPKGPPGPQGPAGEQGPR-----GDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPG 102 Query: 586 PTAGAEAEGSGLGWGSDVGSGSGDLVGSEQL--LRGPPGPPGPPGLPGIPGKPGTDVFMG 643 P G G + + + G + G QL ++GP GP GP G PG G PG F G Sbjct: 103 PP------GLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQG 156 Query: 644 PPGSPGE---DGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDP---- 696 PG PGE GP G GPPGP G+PG DG G PG GE+G GP G+ G G P Sbjct: 157 NPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPG 216 Query: 697 --GNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFE-----DTEGSGSTQ 749 G+RG PG G KG+AG PGV G G PG G PGP GL E +G+ Sbjct: 217 VKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARG 276 Query: 750 LLNEPKLSRPTAAI---------GLKGEKGDRGPKGERGMDGA-SIVGPPGPRGPPGHIK 799 +P + P + G G KG+ GP G RG +GA G PG G PG Sbjct: 277 NDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAG 336 Query: 800 VLSNSLINITHGFMNFSDIPELVGP---PGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKG 856 N + G + P + G PGP G PG G GP GPKG TG PG G KG Sbjct: 337 ASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKG 396 Query: 857 EQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGL 916 EQG KGEPG + P G++G+ G G PG +GP GPP GE G PG G PG Sbjct: 397 EQGPKGEPGPAGPQGAP--GPAGEEGKRGARGEPGGVGPIGPP---GERGAPGNRGFPGQ 451 Query: 917 NGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGS 976 +GL G KG PG +GP GL GP G G PG RP PG Sbjct: 452 DGLAGPKGAPG--ERGPSGLAGPKGANGDPG--------------RP--------GEPGL 487 Query: 977 PELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFK 1036 P G G+ G G G G G+ G GPPGP +G+ G GF Sbjct: 488 PGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGP-----------QGARGQPGVMGFP 536 Query: 1037 GEKGEKGDIN--GSFLMSGPPGLPGNPGPAGQKGET----VVGPQGPPGAPGLPGPPGF- 1089 G KG G+ G + G PGL G PG G+ G GP G G G PGP GF Sbjct: 537 GPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQ 596 Query: 1090 GRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSR 1132 G PG PGPPG G PG + G A A PG GP G+ G PG R Sbjct: 597 GLPGPPGPPGEGGKPGDQGVPGEAGA-PGLVGPRGERGFPGER 638 Score = 366 bits (939), Expect = e-101 Identities = 261/690 (37%), Positives = 306/690 (44%), Gaps = 103/690 (14%) Query: 527 GSPPPDGPPLPLPTVAPERWI-------TPAQREHVGMKGQAGPKGEKGDAGEE-LPGPP 578 G P GPP P P+ + P +G +G GP G+ GD GE PG Sbjct: 135 GPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKA 194 Query: 579 EPSGPVGP--------TAGAEAEGSGLGW-GSDVGSGSGDLVGSEQLLRGP-----PGPP 624 GP GP T G G+ G D G G + P PGP Sbjct: 195 GERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPM 254 Query: 625 GPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGAR 684 GP GLPG G+ G G G+ G+ GPAG PGP GP G PG GA G G G GAR Sbjct: 255 GPRGLPGERGRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGAR 314 Query: 685 GPNGSVGEKGDPGNRGLPGP------------PGKKGQAGPPGVMGPPGPPGPPGPPGP- 731 GP G+ G +G+PG G PGP PG KG AG PG+ G PG PGP GPPGP Sbjct: 315 GPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQ 374 Query: 732 GCTMGLGFEDTEG-------SGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGAS 784 G T LG + G G EP + P A G GE+G RG +GE G G Sbjct: 375 GATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPG--GVG 432 Query: 785 IVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKG 844 +GPPG RG PG+ + G L GP G +G PG PG PG G +G Sbjct: 433 PIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARG 492 Query: 845 DTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGE 904 TG PG G +G+ G G PG P + G +G+PG+ G PGP G G PG GE Sbjct: 493 LTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQ--GARGQPGVMGFPGPKGANGEPGKAGE 550 Query: 905 FGLPGRP---GRPGLNGLKGTKGDPGVI----------MQGPPGLPGPPGPPGPPG---- 947 GLPG P G PG +G G G PG GP G G PGPPGPPG Sbjct: 551 KGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGK 610 Query: 948 ----AVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGD 1003 V GA + R P + PG+ L G+ G G+ G G+ G G Sbjct: 611 PGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGP 670 Query: 1004 QGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDI-----------NGSFLMS 1052 GAQGPPG L + GE G G G KG++GD+ +G ++ Sbjct: 671 PGAQGPPG-----------LQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLT 719 Query: 1053 GPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPG-FGRPGDPGPPGPPGPPGPPAILG 1111 GP G PG G G+KGE VGP GP G+ G G PG G G PGP G GPPG G Sbjct: 720 GPIGPPGPAGANGEKGE--VGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPG 777 Query: 1112 AA-----------VALPGPPGPPGQPGLPG 1130 A PGP GP G PG G Sbjct: 778 AKGEQGEAGQKGDAGAPGPQGPSGAPGPQG 807 Score = 358 bits (918), Expect = 3e-98 Identities = 330/1014 (32%), Positives = 398/1014 (39%), Gaps = 164/1014 (16%) Query: 205 GNAGATGLERFTGSLQQLTVHPDPRTPEELCDPEESSASGETSGLQEADGVAEILEAVTY 264 G AGA G++ +GS + P P P L + +G + DG Sbjct: 231 GEAGAPGVKGESGSPGE-NGSPGPMGPRGLPGERGRTGPAGAAGARGNDG---------- 279 Query: 265 TQASPKEAKVEPINTPPTPSSPFEDMELSGEPVPEGTLETTNMSIIQHSSPKQGS-GEIL 323 Q P PP P P G P +G T + QG GE Sbjct: 280 -QPGPAG--------PPGPVGPAGGPGFPGAPGAKGEAGPTGA---RGPEGAQGPRGEPG 327 Query: 324 NDTLEGVHSVDGDPITDSGSGAGAFLDIAEEKNLAATAAGLAEVPISTAGEAEASSVPTG 383 G G+P TD GA +A A G+A P Sbjct: 328 TPGSPGPAGASGNPGTDGIPGAKG----------SAGAPGIAGAPGFPGPRGPPGPQGAT 377 Query: 384 GPTLSMSTENPEEGVT-----------PGPDNEERLAATAAGEAEALA-SMPGEVEASGV 431 GP L + E G+ PGP + A E + A PG V G Sbjct: 378 GP-LGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIG- 435 Query: 432 APGELDLSMSAQSLGEEATVGPSSEDSLTTAAAATEVSLSTFEDEEASGVPTDGLAPLTA 491 PGE + G++ GP A E S + G D P Sbjct: 436 PPGERGAPGNRGFPGQDGLAGPKG--------APGERGPSGLAGPK--GANGDPGRPGEP 485 Query: 492 TMAPERAVTSGPGDEEDLAAATTEEPLITAGGEESGSPPPDGPPLPLPTVAPERWITPAQ 551 + R +T PGD P G SG+P DG P P P Q Sbjct: 486 GLPGARGLTGRPGDAG---------PQGKVG--PSGAPGEDGRPGP-----PGPQGARGQ 529 Query: 552 REHVGMKGQAGPKGEKGDAGEE-LPGPPEPSGPVGPTA--GAEAEGSGLGWGSDVGSGSG 608 +G G G GE G AGE+ LPG P G G GA G + G Sbjct: 530 PGVMGFPGPKGANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGA 589 Query: 609 DLVGSEQLLRGPPGPPGPPGLPG---IPGKPGTDVFMGP--------------------- 644 Q L GPPGPPG G PG +PG+ G +GP Sbjct: 590 PGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGP 649 Query: 645 ---PGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGL 701 PG+PG DGP G GP GP PG G GL GM GE+GA G G G++GD G +G Sbjct: 650 RGLPGTPGTDGPKGASGPAGP---PGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGP 706 Query: 702 PGPPGKKGQAGPPGVMGPPGPPG---------PPGPPGPGCTMGLGFE--DTEGSGSTQL 750 G PGK G G G +GPPGP G PPGP G G E +T G Sbjct: 707 EGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGF 766 Query: 751 LNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITH 810 P A G +GE G +G G G G S G PGP+GP G Sbjct: 767 AGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPS--GAPGPQGPTGVTGPKGARGAQGPP 824 Query: 811 GFMNFSDIPELVGPPGPDGLPGLPGFPGP------RGPKGDTGLPGFPGLKGEQGEKGEP 864 G F VGPPG +G PG PG PGP +G +GD+G PG G G QG G P Sbjct: 825 GATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPP 884 Query: 865 GAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKG 924 G G+ G+ G GA GP GP+G G +G GLPG+ G G GL G G Sbjct: 885 GE-----------KGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSG 933 Query: 925 DPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHG 984 +PG QG PG G GPPGP G G P P PG G Sbjct: 934 EPG--KQGAPGASGDRGPPGPVGP----PGLTGPAGEPGREGSPGADGPPGRDGAAGVKG 987 Query: 985 VKGEKGSWGLPGS---------------KGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGE 1029 +GE G+ G PG+ +G++G+ GAQGP GP + +G Sbjct: 988 DRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAG--ARGIQGPQGP 1045 Query: 1030 NGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGET-VVGPQGPPGAPGLPGPPG 1088 GDKG GE GE+G + G +G GLPG PGP+G +G + GP GP G PG GP G Sbjct: 1046 RGDKGEAGEPGERG-LKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSG 1104 Query: 1089 F-GRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNLVTAFSNM 1141 G G PGP GPPGP G G A PG PGPPG PG PG ++AF+ + Sbjct: 1105 KDGANGIPGPIGPPGPRGRSGETGPA-GPPGNPGPPGPPGPPGPGIDMSAFAGL 1157 Score = 308 bits (789), Expect = 2e-83 Identities = 216/551 (39%), Positives = 240/551 (43%), Gaps = 128/551 (23%) Query: 624 PGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGA 683 PGP G G PG +GP G PG GPAGE GP G G KGEKGA Sbjct: 31 PGPKGQKGEPGD--IKDIVGPKGPPGPQGPAGEQGPRGDRGD------------KGEKGA 76 Query: 684 RGPNGSVGEKGDPGNRGLPGPPGKKG---------------------------QAGPPGV 716 GP G GE G PGN G PGPPG G GP G Sbjct: 77 PGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGP 136 Query: 717 MGPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKG 776 MGP GPPGP G PGP GF+ G EP +S P G G G G G Sbjct: 137 MGPRGPPGPAGAPGP-----QGFQGNPGEP-----GEPGVSGPMGPRGPPGPPGKPGDDG 186 Query: 777 ERGMDG-ASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPG 835 E G G A GPPGP+G G G PG G+ G G Sbjct: 187 EAGKPGKAGERGPPGPQGARG------------------------FPGTPGLPGVKGHRG 222 Query: 836 FPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLER----LMGKKGEPGMHGAPG 891 +PG G KG+ G PG G G GE G PG + +P ER G G G G PG Sbjct: 223 YPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPG 282 Query: 892 PMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVIN 951 P GP GP G G G PG PG G G G +G G QGP G PG PG PGP GA Sbjct: 283 PAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGA--QGPRGEPGTPGSPGPAGA--- 337 Query: 952 IKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPG 1011 + +PG+ G+ G KGS G PG G G G +GPPG Sbjct: 338 -------------------SGNPGT------DGIPGAKGSAGAPGIAGAPGFPGPRGPPG 372 Query: 1012 PPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGET- 1070 P L GE G GFKGE+G KG+ GP G G PGPAG++G+ Sbjct: 373 PQGATGPLGP--KGQTGEPGIAGFKGEQGPKGE-------PGPAGPQGAPGPAGEEGKRG 423 Query: 1071 ------VVGPQGPPGAPGLPGPPGF-GRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPP 1123 VGP GPPG G PG GF G+ G GP G PG GP + G A G PG P Sbjct: 424 ARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGA-NGDPGRP 482 Query: 1124 GQPGLPGSRNL 1134 G+PGLPG+R L Sbjct: 483 GEPGLPGARGL 493 Score = 34.7 bits (78), Expect = 0.65 Identities = 17/39 (43%), Positives = 18/39 (46%) Query: 1094 DPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSR 1132 D PGP G G P + V GPPGP G G G R Sbjct: 27 DVRQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPR 65 >gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo sapiens] Length = 1818 Score = 374 bits (960), Expect = e-103 Identities = 372/1238 (30%), Positives = 481/1238 (38%), Gaps = 231/1238 (18%) Query: 52 PSSVSFVTGY--------GGFPAYSFGPGANVGRPARTLIPS-TFFRDFAISVVVKPSST 102 P +S TG+ G AY A + P + L P TF DF+I VKP Sbjct: 51 PEGISKTTGFCTNRKNSKGSDTAYRVSKQAQLSAPTKQLFPGGTFPEDFSILFTVKPKKG 110 Query: 103 RGGVLFAITDAFQKVIYLGLRLSGVEDGHQRIILYYTEPGSHVSQEAAAF-SVPVMTHRW 161 L +I + G++ GVE G + L+ G ++ F +V + +W Sbjct: 111 IQSFLLSIYNEH------GIQQIGVEVGRSPVFLFEDHTGKPAPEDYPLFRTVNIADGKW 164 Query: 162 NRFAMIVQGEEVTLLVNCEEHSRIPFQRSSQALAFESSAGIFMGNAGATGLERFTGSLQQ 221 +R A+ V+ + VT++V+C++ + P RS +A+ + GI + E F G +QQ Sbjct: 165 HRVAISVEKKTVTMIVDCKKKTTKPLDRSERAIV--DTNGITVFGTRILDEEVFEGDIQQ 222 Query: 222 LTVHPDPRTPEELCDPEESSASGETSGLQEADGVAEILEAVTYTQASPKEAKVEPINTPP 281 + DP+ + C E S ++S +PK A+ + Sbjct: 223 FLITGDPKAAYDYC--EHYSPDCDSS--------------------APKAAQAQEPQIDE 260 Query: 282 TPSSPF-EDMELSGEPVPEGTLETTNMSIIQHSSPKQGSGEILNDTLEGVHSVDGDPITD 340 S F + M E + + T + SS K+ S + GV + Sbjct: 261 KKKSNFKKKMRTVATKSKEKSKKFTPPKSEKFSSKKKKSYQASAKAKLGVKA-------- 312 Query: 341 SGSGAGAFLDIAEEKNLAATAAGLAEVPISTAGEAEASSVPTGGPTLSMSTENPEEGVTP 400 +D +E N + E P +G E + P + TE G Sbjct: 313 ------NIVDDFQEYNYGTMESYQTEAPRHVSGTNEPN------PVEEIFTEEYLTG--E 358 Query: 401 GPDNEERLAATAAGEAEALASMPGEVEASGVAPGELDLSMSAQSLGEEATVGPSSEDSLT 460 D++ + + E + + ++ G GE D + E+ P +E+ Sbjct: 359 DYDSQRKNSEDTLYENKEIDGRDSDLLVDGDL-GEYDFYEYKEY--EDKPTSPPNEEFGP 415 Query: 461 TAAAATEVSLSTFEDEEASGVPTDGLAPLTATMAPERAVTSGPGDEEDLAAATTEEPLIT 520 A T+++ ++ A G G A + P V PG A P + Sbjct: 416 GVPAETDITETSINGHGAYG--EKGQKGEPAVVEPGMLVEGPPGPAG--PAGIMGPPGLQ 471 Query: 521 AGGEESGSP----PPDGPPLP----LPTVAPERWITPAQREHVGMKG------QAGPKGE 566 G P PP P LP LP + P + G KG +A + Sbjct: 472 GPTGPPGDPGDRGPPGRPGLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEAQAQAI 531 Query: 567 KGDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGP 626 A L GPP P G G GS S SGD Q RG GPPGP Sbjct: 532 LQQARIALRGPPGPMGLTGRPGPVGGPGS-----SGAKGESGD--PGPQGPRGVQGPPGP 584 Query: 627 PGLPGIPGKPGTDVFMGPPGSP---------------------GEDGPAGEPGPPGPEGQ 665 G PG G+PG D G PG P GE GP G PGPPG +G Sbjct: 585 TGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGDDGM 644 Query: 666 PGVD---GATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGP 722 G D G GLPG G +G GP G+ G G PG G+ GPPG KG GP G GPPG Sbjct: 645 RGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQ 704 Query: 723 PGPPGPPG-PGCTMGLGFEDTEG-SGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGM 780 G PGP G PG +G +G G L P P G +G+ G++G G G Sbjct: 705 QGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGP 764 Query: 781 DGASIVGPPGPRGPPG--HIKVLSNSL-INITHGFMNF--------------------SD 817 G +G PGPRG G ++ L S GF F D Sbjct: 765 QGP--IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPGFKGDMGLKGDRGEVGQIGPRGED 822 Query: 818 IPE-------LVGPPGPD---------GLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEK 861 PE G PGP G+PGLPG+PG +GPKG TG PGFPG GE+G + Sbjct: 823 GPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPGRQGPKGSTGFPGFPGANGEKGAR 882 Query: 862 ---GEPGAILTEDIPLER----------LMGKKGEPGMHGAPGP---------------M 893 G+PG R G KG G G PGP Sbjct: 883 GVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFP 942 Query: 894 GPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPG----VIMQGPPGLPGP------PGPP 943 GPKGPPG G+ GLPG PG+ G G +G G PG V QGP G GP PGPP Sbjct: 943 GPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPP 1002 Query: 944 GPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGD 1003 GPPG + GA + + G L F G +G G+ G PG KG +G Sbjct: 1003 GPPGEQ-GLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGP 1061 Query: 1004 QGAQGPPGPPLDLAYL----------RHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSG 1053 QG GP G P + R G G+KG GEKG +G G + G Sbjct: 1062 QGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPA-GRDGVQG 1120 Query: 1054 PPGLPGNPGPAGQKGET----------------VVGPQGPPGAPGLPGPPGFGRPGDPGP 1097 P GLPG GPAG GE G GPPG PGL GP G PG G Sbjct: 1121 PVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGP--VGAPGIAGG 1178 Query: 1098 PGPPGPPGPPAILG-----AAVALPGPPGPPGQPGLPG 1130 G PGP G + G A PGPPGP G GLPG Sbjct: 1179 DGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPG 1216 Score = 355 bits (910), Expect = 2e-97 Identities = 271/709 (38%), Positives = 312/709 (44%), Gaps = 128/709 (18%) Query: 525 ESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEE----LPGPPEP 580 E G P GPP + I P G+ G+AGP+G G G PG Sbjct: 629 ERGPQGPPGPPGDDGMRGEDGEIGPR-----GLPGEAGPRGLLGPRGTPGAPGQPGMAGV 683 Query: 581 SGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDV 640 GP GP +G G G L G + + GPPG GP G PG+ G PG D Sbjct: 684 DGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPI-GPPGEKGPQGKPGLAGLPGAD- 741 Query: 641 FMGPPGSPGEDGPAGE------PGPPGPEGQPG---VDGATGLPGMKGEKGARGPNGSVG 691 GPPG PG++G +GE PGP GP G PG V GA G+ G+KG KG +G +G G Sbjct: 742 --GPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG 799 Query: 692 EKGDPG------------NRGLPGPPGKKGQAGPPGVMGP------------PGPPGPPG 727 KGD G RG GP G KG+AGP G GP PG PG PG Sbjct: 800 FKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYPG 859 Query: 728 PPGPGCTMGL-GFEDTEGS-GSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGAS- 784 GP + G GF G G+ + +P G +G +G RGP G+ G G S Sbjct: 860 RQGPKGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG 919 Query: 785 ---IVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRG 841 GPPG RGP G G + F GPPG DGLPG PG G G Sbjct: 920 GDGPPGPPGERGPQG------------PQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETG 967 Query: 842 PKGDTGLPGFPGLKGEQGEKGEPGAILTEDIP----------LERLMGK---KGEPGMHG 888 +G TG PG G+ G QG GE G I P L GK KG+PG G Sbjct: 968 FQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQG 1027 Query: 889 APGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVI----------MQGPPGLPG 938 G GP G G GE GLPG G PGL G +G +G PG + GP GLPG Sbjct: 1028 ISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPG 1087 Query: 939 PPGPPGPPG-----AVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWG 993 PGP GPPG KG P R + PV P P G G+KG G Sbjct: 1088 RPGPQGPPGPAGEKGAPGEKGPQGPAG-RDGVQGPVGLPGPAGPA--GSPGEDGDKGEIG 1144 Query: 994 LPGSKGEKGDQGAQGPPGPP-LDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMS 1052 PG KG KGD+G GPPGPP L + GE G +G +G G+KGD G+ Sbjct: 1145 EPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGD-EGARGFP 1203 Query: 1053 GPP---GLPGNPGPAGQKGET-VVGPQGPPGAPGLPGPP-------------------GF 1089 GPP GL G PGP G+KGE VGP GPPG PG GP G Sbjct: 1204 GPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGV 1263 Query: 1090 GRPGDPGPPGPPGPPGPPAILG--------AAVALPGPPGPPGQPGLPG 1130 G G+PG G PGPPG + G PG GPPG G PG Sbjct: 1264 GEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPG 1312 Score = 353 bits (907), Expect = 5e-97 Identities = 252/643 (39%), Positives = 293/643 (45%), Gaps = 107/643 (16%) Query: 517 PLITAGGEESGSPP----PDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGE 572 P T+GG+ PP P GP P+ P+ P ++ G+ G G +GE G G+ Sbjct: 914 PKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKD--GLPGHPGQRGETGFQGK 971 Query: 573 ELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGI 632 GPP P G VGP G E +G E+ GPPGPPG GLPG Sbjct: 972 T--GPPGPGGVVGPQ-GPTGETGPIG---------------ERGHPGPPGPPGEQGLPGA 1013 Query: 633 PGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGE 692 GK G GP G G+DGPAG G PG G PG GA GL G +G +G GP GS GE Sbjct: 1014 AGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGE 1073 Query: 693 KGDPGNRG---LPGPPGKKGQAGPPGVMGPPGPPGPPGP------------PGPGCTMGL 737 +G G G LPG PG +G GP G G PG GP GP PGP G Sbjct: 1074 RGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGS 1133 Query: 738 GFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGA----SIVGPPGPRG 793 ED G + EP G KG+KG+ GP G G+ G I G G G Sbjct: 1134 PGED----GDKGEIGEPGQK------GSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPG 1183 Query: 794 PPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPG 853 P G + GF GPPGP GL GLPG PG +G GD G G PG Sbjct: 1184 PRGQQGMFGQKGDEGARGFP---------GPPGPIGLQGLPGPPGEKGENGDVGPMGPPG 1234 Query: 854 LKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGR 913 G +G +G GA G +G PG G+ G +G KG PG E G PG PG Sbjct: 1235 PPGPRGPQGPNGAD-----------GPQGPPGSVGSVGGVGEKGEPG---EAGNPGPPGE 1280 Query: 914 PGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAH 973 G+ G KG +G+ G GPPG GPPG GPPG KG P+ P D Sbjct: 1281 AGVGGPKGERGEKGEA--GPPGAAGPPGAKGPPGDD-GPKGNPGPVG------FPGDPGP 1331 Query: 974 PGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDK 1033 PG P GV G+KG G PG G G G GPPGPP G G + Sbjct: 1332 PGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPP--------GKRGPPGAAGAE 1383 Query: 1034 GFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPG-FGRP 1092 G +GEKG KG+ +G G PG GP G +G G GP G G+PGP G G P Sbjct: 1384 GRQGEKGAKGE-------AGAEGPPGKTGPVGPQGP--AGKPGPEGLRGIPGPVGEQGLP 1434 Query: 1093 GDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNLV 1135 G G GPPGP GPP + G L G PG G+ G PG L+ Sbjct: 1435 GAAGQDGPPGPMGPPGLPG----LKGDPGSKGEKGHPGLIGLI 1473 Score = 337 bits (864), Expect = 5e-92 Identities = 245/635 (38%), Positives = 288/635 (45%), Gaps = 125/635 (19%) Query: 515 EEPLITAGGEES--GSPPPDG-----PPLPLPTVAPERWITPAQREHVGMKGQAGPKG-- 565 E+ L A G+E G P P G P L ER + AQ G+KG GP+G Sbjct: 1007 EQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAP-GLKGGEGPQGPP 1065 Query: 566 -------EKGDAGEE----LPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSE 614 E+G AG LPG P P GP GP A G G G Sbjct: 1066 GPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDG-------- 1117 Query: 615 QLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGL 674 ++GP G PGP G G PG+ G +G PG G G GE GPPGP G G GA G+ Sbjct: 1118 --VQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGI 1175 Query: 675 PGMKGEKGARGPNGSVGEKGDPGNRG------------LPGPPGKKGQAGPPGVMGPPGP 722 G GE G RG G G+KGD G RG LPGPPG+KG+ G G MGPPGP Sbjct: 1176 AGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGP 1235 Query: 723 PGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDG 782 PGP GP GP G + +G + ++G GEKG+ G G G G Sbjct: 1236 PGPRGPQGPN-----GADGPQGPPGS-----------VGSVGGVGEKGEPGEAGNPGPPG 1279 Query: 783 -ASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRG 841 A + GP G RG G GPPG G PG G PG G Sbjct: 1280 EAGVGGPKGERGEKGE------------------------AGPPGAAGPPGAKGPPGDDG 1315 Query: 842 PKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGH 901 PKG+ G GFPG + G GEPG + + ++ G+ G+PG G PGP G GPPG Sbjct: 1316 PKGNPGPVGFPG---DPGPPGEPGPAGQDGVGGDK--GEDGDPGQPGPPGPSGEAGPPGP 1370 Query: 902 KGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPG--AVINIKGAIFPI 959 G+ G PG G G G KG KG+ G +GPPG GP GP GP G ++G P+ Sbjct: 1371 PGKRGPPGAAGAEGRQGEKGAKGEAGA--EGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV 1428 Query: 960 PVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYL 1019 + +P G P + G+ G KG PGSKGEKG G G GPP + Sbjct: 1429 GEQG---LPGAAGQDGPPGPMGPPGLPGLKGD---PGSKGEKGHPGLIGLIGPPGE---- 1478 Query: 1020 RHFLNNLKGENGDKGFKGEKGE---KGDIN-----GSFLMSGPPGLPGNPGPAGQKGETV 1071 +GE GD+G G +G KGD G GPPGLPG GP G KG T Sbjct: 1479 -------QGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGST- 1530 Query: 1072 VGPQGPPGAPGLPGPPGFGRPGDPGPPGPPGPPGP 1106 GP G G GLPGPPG PGPPG P P Sbjct: 1531 -GPAGQKGDSGLPGPPG-----SPGPPGEVIQPLP 1559 Score = 286 bits (731), Expect = 1e-76 Identities = 223/610 (36%), Positives = 259/610 (42%), Gaps = 99/610 (16%) Query: 400 PGPDNEERLAATAAGEA-------EALASMPGEVEASGVAPGELDLSMSAQSLGEEATVG 452 PGP E+ L A E + ++ G G PGE L + + G + G Sbjct: 1002 PGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGF-PGERGLPGAQGAPGLKGGEG 1060 Query: 453 PSSEDSLTTAAAATEVSLSTFEDEEASGVPTDGLAPLTATMAPERAVTSGPGDEEDLAAA 512 P + E T G L P+ PG + A Sbjct: 1061 PQGPPGPVGSPG------------ERGSAGTAGPIGLPGRPGPQ----GPPGPAGEKGAP 1104 Query: 513 TTEEPLITAGGEESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGE 572 + P AG + G P G P P +P + G G+ G KG KGD GE Sbjct: 1105 GEKGPQGPAGRD--GVQGPVGLPGPAGPAG-----SPGEDGDKGEIGEPGQKGSKGDKGE 1157 Query: 573 E-LPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGS--EQLLRGPPGPPGPPGL 629 PGPP GPVG A G G G G + G ++ RG PGPPGP GL Sbjct: 1158 NGPPGPPGLQGPVG------APGIAGGDGEPGPRGQQGMFGQKGDEGARGFPGPPGPIGL 1211 Query: 630 PGIPGKPGT-----DVF-MGPPGSPGEDGPAGEPGPPGPEGQPGVDGATG---------- 673 G+PG PG DV MGPPG PG GP G G GP+G PG G+ G Sbjct: 1212 QGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGE 1271 Query: 674 --LPGMKGEKGARGPNGSVGEKGD---------PGNRGLPGPPGKKGQAGPPGVMGPPGP 722 PG GE G GP G GEKG+ PG +G PG G KG GP G G PGP Sbjct: 1272 AGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGP 1331 Query: 723 PGPPGPPGPGCTMGLGFEDTE--------GSGSTQLLNEPKLSRPTAAIGLKGEKGDRGP 774 PG PGP G G ED + SG P P A G +G +G++G Sbjct: 1332 PGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGA 1391 Query: 775 KGERGMDG-ASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGL 833 KGE G +G GP GP+GP G G IP GP G GLPG Sbjct: 1392 KGEAGAEGPPGKTGPVGPQGPAG------------KPGPEGLRGIP---GPVGEQGLPGA 1436 Query: 834 PGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLER-LMGKKGEPGMHGAPGP 892 G GP GP G GLPG G G +GEKG PG I P E+ G +G PG G+PG Sbjct: 1437 AGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGA 1496 Query: 893 MGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQ-GPPGLPGPPGPPGPPGAVIN 951 G G PG G G PG PG PG G KG KG G Q G GLPGPPG PGPPG VI Sbjct: 1497 KGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQ 1556 Query: 952 IKGAIFPIPV 961 P+P+ Sbjct: 1557 ------PLPI 1560 Score = 208 bits (529), Expect = 3e-53 Identities = 140/369 (37%), Positives = 162/369 (43%), Gaps = 69/369 (18%) Query: 555 VGMKGQAGPKGEKGDAGEE----LPGPPEPSGPVGPTA--------------------GA 590 +G++G GP GEKG+ G+ PGPP P GP GP G Sbjct: 1209 IGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGE 1268 Query: 591 EAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPG------KPGTDVFMGP 644 E G + G G E+ GPPG GPPG G PG PG F G Sbjct: 1269 PGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGD 1328 Query: 645 PGSPGEDGPAGE------------PGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGE 692 PG PGE GPAG+ PG PGP G G G G PG +G GA G G GE Sbjct: 1329 PGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGE 1388 Query: 693 KGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLN 752 KG G G GPPGK G GP G G PGP G G PGP GL G+ Sbjct: 1389 KGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGL-------PGAAGQDG 1441 Query: 753 EPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGF 812 P P GLKG+ G +G KG G+ G ++GPPG +G G + T G Sbjct: 1442 PPGPMGPPGLPGLKGDPGSKGEKGHPGLIG--LIGPPGEQGEKGDRGLPG------TQGS 1493 Query: 813 MNFSDIPELVGPPGPDGLPGLPGFPGPRGPKG------------DTGLPGFPGLKGEQGE 860 + GP GP G PG PG PGP+GPKG D+GLPG PG G GE Sbjct: 1494 PGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGE 1553 Query: 861 KGEPGAILT 869 +P IL+ Sbjct: 1554 VIQPLPILS 1562 Score = 204 bits (520), Expect = 4e-52 Identities = 153/418 (36%), Positives = 180/418 (43%), Gaps = 123/418 (29%) Query: 767 GEKGDRGPKGERGM--DGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGP 824 G G++G KGE + G + GPPGP GP G ++GP Sbjct: 432 GAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAG------------------------IMGP 467 Query: 825 PGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEP 884 PG G G PG PG RGP PG PGL G G G PG +L P Sbjct: 468 PGLQGPTGPPGDPGDRGP------PGRPGLPGADGLPGPPGTMLML-------------P 508 Query: 885 GMHGAPGPMGP--------------------KGPPGHKGEFGLPGRPGRPGLNGLKGTKG 924 +G G GP +GPPG G G PG G PG +G KG G Sbjct: 509 FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 568 Query: 925 DPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHG 984 DPG QGP G+ GPPGP G PG R PG P G Sbjct: 569 DPGP--QGPRGVQGPPGPTGKPGK-------------RGRPGADGGRGMPGEP------G 607 Query: 985 VKGEKGSWGLPG---SKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGE 1041 KG++G GLPG KG +G++G QGPPGPP D + ++GE+G+ G +G GE Sbjct: 608 AKGDRGFDGLPGLPGDKGHRGERGPQGPPGPPGD--------DGMRGEDGEIGPRGLPGE 659 Query: 1042 KGDINGSFLMSGPPGLPGNPGPAGQKG----ETVVGPQGPPGAPG---------LPGPPG 1088 G G G PG PG PG AG G + +GPQG PG PG LPGP G Sbjct: 660 AGP-RGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQG 718 Query: 1089 -FGRPGDPGPPGPPG---------PPGPPAILGAA--VALPGPPGPPGQPGLPGSRNL 1134 G PG+ GP G PG PPG P G + GPPGP G G PG R + Sbjct: 719 PIGPPGEKGPQGKPGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGV 776 Score = 155 bits (393), Expect = 2e-37 Identities = 133/397 (33%), Positives = 162/397 (40%), Gaps = 49/397 (12%) Query: 363 GLAEVPISTAGEAEASSVPTGGPTLSMSTENPE-EGVTPGPDNEERLAATAAGEAEALAS 421 GL +P + E V GP P+ GP + G E Sbjct: 1210 GLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEK--G 1267 Query: 422 MPGEVEASGVAPGELDLSMSAQSLGEEATVGPSSEDSLTTAAAATEVSLSTFEDEEASGV 481 PGE G PGE + GE+ GP AA + D+ G Sbjct: 1268 EPGEAGNPG-PPGEAGVGGPKGERGEKGEAGPPG-------AAGPPGAKGPPGDDGPKGN 1319 Query: 482 PTDGLAPLTATMAPERAVTSGPGDEEDLAAATTEEPLITAGGE--ESGSPPPDGPPLPLP 539 P P+ P GP ++ + GG+ E G P GPP P Sbjct: 1320 P----GPVGFPGDPGPPGEPGPAGQDGV------------GGDKGEDGDPGQPGPPGPSG 1363 Query: 540 TVAPERWITPAQREH---VGMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEG-S 595 P P +R G +G+ G KG KG+AG E GPP +GPVGP A G Sbjct: 1364 EAGPPG--PPGKRGPPGAAGAEGRQGEKGAKGEAGAE--GPPGKTGPVGPQGPAGKPGPE 1419 Query: 596 GL-GWGSDVGS-GSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPG------S 647 GL G VG G G + GPPGP GPPGLPG+ G PG+ G PG Sbjct: 1420 GLRGIPGPVGEQGLPGAAGQD----GPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGP 1475 Query: 648 PGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGK 707 PGE G G+ G PG +G PG G G+PG G G GP G G +G GN+G GP G+ Sbjct: 1476 PGEQGEKGDRGLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQ 1535 Query: 708 KGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEG 744 KG +G PG G PGPPG P P + TEG Sbjct: 1536 KGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRRHTEG 1572 Score = 35.8 bits (81), Expect = 0.29 Identities = 21/66 (31%), Positives = 27/66 (40%), Gaps = 5/66 (7%) Query: 1074 PQGPPG---APGLPGPPGFGRPG--DPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGL 1128 P PP PG+P G G G G PA++ + + GPPGP G G+ Sbjct: 405 PTSPPNEEFGPGVPAETDITETSINGHGAYGEKGQKGEPAVVEPGMLVEGPPGPAGPAGI 464 Query: 1129 PGSRNL 1134 G L Sbjct: 465 MGPPGL 470 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 367 bits (942), Expect = e-101 Identities = 259/701 (36%), Positives = 306/701 (43%), Gaps = 126/701 (17%) Query: 527 GSPPPDGPPLPLPTVAPERWITPAQREHVGM---KGQAGPKGEKGDAGEE---------- 573 G+ P+G P V P+ +P +E G+ KG GP+G +G AG Sbjct: 83 GAEVPEGECCP---VCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPG 139 Query: 574 LPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIP 633 LPGPP P GP GP L +G D S G V GP GP GP GLPG P Sbjct: 140 LPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVP------GPMGPSGPRGLPGPP 193 Query: 634 GKPGTDVFMGPPGSPGE---------------------DGPAGEP------GPPGPEGQP 666 G PG F GPPG PGE DG AG+P GPPGP+G Sbjct: 194 GAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGAR 253 Query: 667 GVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPP 726 G+ G GLPGMKG +G G +G+ G+ G G +G PG PG+ G G G G PG G P Sbjct: 254 GLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRP 313 Query: 727 GPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPT------AAIGLKGEKGDRGPKGERGM 780 G PGP G G+T P + P A+G KGE G +GP+G G Sbjct: 314 GAPGPAGARG-------NDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGP 366 Query: 781 DGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFP--- 837 G + G PGP GP G N + G + P + G PG G G P P Sbjct: 367 QG--VRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARG-PSGPQGP 423 Query: 838 -GPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIP----LERLMGKKGEPGMHGAPGP 892 GP GPKG++G PG PG KG+ G KGEPG + + P E G +GEPG G PGP Sbjct: 424 GGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGP 483 Query: 893 ------------------------------MGPKGPPGHKGEFGLPGRPGRPGLNGLKGT 922 GP GP G GE G PG G PG GL G+ Sbjct: 484 PGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGS 543 Query: 923 KGDPG----VIMQGPPGLPGPPGPPGPPGA--VINIKGAIFPIPVRPHCKMPVDTAHPGS 976 G PG GP G G PGPPGPPGA + G P + PG Sbjct: 544 PGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGP 603 Query: 977 PELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFK 1036 P + G GE G+ G PG G G++G QGP G P L G G G Sbjct: 604 PGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSP--------GFQGLPGPAGPPGEA 655 Query: 1037 GEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPG-FGRPGDP 1095 G+ GE+G + G GP G G G G++G V GP GP G G G PG G GD Sbjct: 656 GKPGEQG-VPGDLGAPGPSGARGERGFPGERG--VQGPPGPAGPRGANGAPGNDGAKGDA 712 Query: 1096 GPPGPPGPPGPPAILG-----AAVALPGPPGPPGQPGLPGS 1131 G PG PG G P + G A LPGP G G G G+ Sbjct: 713 GAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGA 753 Score = 357 bits (916), Expect = 4e-98 Identities = 259/695 (37%), Positives = 301/695 (43%), Gaps = 145/695 (20%) Query: 527 GSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEE----LPGPPEPSG 582 G+ GPP P P P VG KG+AGP+G +G G + PGPP P+G Sbjct: 326 GATGAAGPPGPTGPAGP-----PGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAG 380 Query: 583 PVGPTAGAEAEGSGLGWGSDVGSGSGDLVG--SEQLLRGPPGPPGPPGLPGIPGKPGTDV 640 GP A+G G++ G G + GP GP GPPG G G+PG Sbjct: 381 AAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPG 440 Query: 641 FMGPPGSPGEDGPAGEPGPPGPEGQPGVDGA------TGLPGMKGEKGA----------- 683 G G+ GE GP G GPPGP G+ G GA TGLPG GE+G Sbjct: 441 SKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADG 500 Query: 684 ----------------RGPNGSVGEKGDPGNRGLPGP---------PGKKGQAGPPGVMG 718 GP GS GE G PG GLPG PG G+ GPPG G Sbjct: 501 VAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAG 560 Query: 719 PPGPPGPPGPPGPGCTMG-LGFEDTEGS-GSTQLLNEPKLSRPTAAIGLKGEKGDRG--- 773 G PGPPGPPG G +GF +G+ G E + P A+G G+ G+ G Sbjct: 561 QDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQG 620 Query: 774 ------PKGERGMDGAS----IVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVG 823 P GERG G + G PGP GPPG G +P +G Sbjct: 621 PPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEA------------GKPGEQGVPGDLG 668 Query: 824 PPGPDGLPGLPGFPG------PRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERL 877 PGP G G GFPG P GP G G G PG G +G+ G PGA ++ P Sbjct: 669 APGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAP---- 724 Query: 878 MGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVI-MQGPPGL 936 G +G PG GA G GPKG G G G G PG+ G+ GL G G PG G G Sbjct: 725 -GLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGE 783 Query: 937 PGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPG 996 GP GP GP GA +GA P D PG P F G G G PG Sbjct: 784 SGPSGPAGPTGA----RGA------------PGDRGEPGPPGPAGFAGPPGADGQ---PG 824 Query: 997 SKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPG 1056 +KGE GD GA+G GPP G G+ G G KG +G +GPPG Sbjct: 825 AKGEPGDAGAKGDAGPPGPAGPA-----GPPGPIGNVGAPGAKGARGS-------AGPPG 872 Query: 1057 LPGNPGPAGQKGETVVGPQGPPGAPGLPGPPG----------------FGRPGDPGPPGP 1100 G PG AG+ VGP GP G G PGPPG GRPG+ GPPGP Sbjct: 873 ATGFPGAAGR-----VGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGP 927 Query: 1101 PGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNLV 1135 PGP G GA G PG PG G+ G R +V Sbjct: 928 PGPAGEKGSPGAD-GPAGAPGTPGPQGIAGQRGVV 961 Score = 353 bits (906), Expect = 6e-97 Identities = 294/848 (34%), Positives = 347/848 (40%), Gaps = 175/848 (20%) Query: 368 PISTAGE-----AEASSVPTGGPTLSMSTENPEEGVTPGPDNEERLAATAA-----GEAE 417 P AGE A PTG P P PG D A G A Sbjct: 459 PPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAG 518 Query: 418 ALASMPGEVEASGVA--PGELDLSMSAQSLGEEATVGP---SSEDSLT----TAAAATEV 468 S PGE G A PG L+ S S G + GP + +D A + Sbjct: 519 PKGS-PGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQA 577 Query: 469 SLSTFEDEE-ASGVPTDGLAPLTATMAPERAVTSGP-GDEEDLAAATTEEPLITAGGEES 526 + F + A+G P G A P AV GP G + + A P AG E Sbjct: 578 GVMGFPGPKGAAGEP--GKAGERGVPGPPGAV--GPAGKDGEAGAQGPPGPAGPAG--ER 631 Query: 527 GSPPPDGPP----LPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSG 582 G P G P LP P P P ++ G G GP G +G+ G PG G Sbjct: 632 GEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERG--FPGERGVQG 689 Query: 583 PVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFM 642 P GP A G+ G+D G G+ PG G PGL G+PG+ G Sbjct: 690 PPGPAGPRGANGAP---GNDGAKGDAGAPGA-------PGSQGAPGLQGMPGERGAAGLP 739 Query: 643 GPPGSPGEDGPAGEPGPPGPEGQPGVDGA------TGLPGMKGEKGARGPNGSVGEKGDP 696 GP G G+ GP G G PG +G G+ G G PG KGE G GP G G +G P Sbjct: 740 GPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAP 799 Query: 697 GNRGLPGPPGKKGQAGPPGV------------------MGPPGPPGPPGPPGPGCTMGL- 737 G+RG PGPPG G AGPPG GPPGP GP GPPGP +G Sbjct: 800 GDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAP 859 Query: 738 GFEDTEGS----------GSTQLLNEPKLSR---PTAAIGLKGEKGDRGPKGERGMDGA- 783 G + GS G+ + P S P G G++G +GP+GE G G Sbjct: 860 GAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRP 919 Query: 784 SIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPK 843 VGPPGP GP G G PG DG G PG PGP+G Sbjct: 920 GEVGPPGPPGPAGE------------------------KGSPGADGPAGAPGTPGPQGIA 955 Query: 844 GDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKG 903 G G+ G PG +GE+G G PG GK+G G G GP GP GPPG G Sbjct: 956 GQRGVVGLPGQRGERGFPGLPGP--------SGEPGKQGPSGASGERGPPGPMGPPGLAG 1007 Query: 904 EFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRP 963 G GR G PG G G G PG +G G GP GPPG PGA Sbjct: 1008 PPGESGREGAPGAEGSPGRDGSPGA--KGDRGETGPAGPPGAPGA--------------- 1050 Query: 964 HCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFL 1023 PG+P + G G++G G G G G GA+GP GP Sbjct: 1051 ----------PGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGP----------- 1089 Query: 1024 NNLKGENGDKGFKGEKGEKG--DINGSFLMSGPPGLPGNPGPAGQKGET-VVGPQGPPGA 1080 +G GDKG GE+G++G G + GPPG PG+PG G G + GP+GPPG+ Sbjct: 1090 ---QGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGS 1146 Query: 1081 PGLPG------------PPG-FGRPGDPGP---PGPPGPPGPPAILGAAVALPGPPGPPG 1124 G PG PPG GR GD GP PGPPGPPGPP A P PP Sbjct: 1147 AGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQ 1206 Query: 1125 QPGLPGSR 1132 + G R Sbjct: 1207 EKAHDGGR 1214 Score = 345 bits (884), Expect = 2e-94 Identities = 275/782 (35%), Positives = 319/782 (40%), Gaps = 133/782 (17%) Query: 400 PGPDNEE-RLAATAAGEAEALASMPGEVEASGVA--PGELDLSMSAQSLGEEATVGPSSE 456 PGP EE + A L PGE G PG ++ GE + GP+ Sbjct: 460 PGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGP 519 Query: 457 DSLTTAAAATEVSLSTFEDEEASGVPTDGLAPLTATMAPERAVTSGPGDEEDLAAATTEE 516 G P + P A + + +T PG Sbjct: 520 ----------------------KGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPG 557 Query: 517 PLITAGGEESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKG---EKGDAGEE 573 P AG + G P P GPP R G+ G GPKG E G AGE Sbjct: 558 P---AG--QDGRPGPPGPP--------------GARGQAGVMGFPGPKGAAGEPGKAGER 598 Query: 574 -LPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSE--QLLRGPPGPPGPPGLP 630 +PGPP GP G A A+G G G GS Q L GP GPPG G P Sbjct: 599 GVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKP 658 Query: 631 GIPGKPGTDVFMGPPGS------PGEDGPAGEPGPPGPEGQ------------------P 666 G G PG GP G+ PGE G G PGP GP G P Sbjct: 659 GEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAP 718 Query: 667 GVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPP 726 G GA GL GM GE+GA G G G++GD G +G G PGK G G G +GPPGP G P Sbjct: 719 GSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAP 778 Query: 727 GPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGAS-I 785 G G G T G+ EP P G G G G KGE G GA Sbjct: 779 GDKGESGPSGPA-GPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGD 837 Query: 786 VGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGD 845 GPPGP GP G + N G GPPG G PG G GP GP G+ Sbjct: 838 AGPPGPAGPAGPPGPIGNV------GAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGN 891 Query: 846 TGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEF 905 G PG PG G++G KG G E P G+ GE G G PGP G KG PG G Sbjct: 892 AGPPGPPGPAGKEGGKGPRG----ETGPA----GRPGEVGPPGPPGPAGEKGSPGADGPA 943 Query: 906 GLPGRPGRPGLNGLKGTKGDPGVIMQ-GPPGLPGPPGPPGP--PGAVINIKGAIFPIPVR 962 G PG PG G+ G +G G PG + G PGLPGP G PG P +G P+ Sbjct: 944 GAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPP 1003 Query: 963 PHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHF 1022 P ++ G+P G +G G G PG+KG++G+ G GPPG P Sbjct: 1004 GLAGPPGESGREGAP------GAEGSPGRDGSPGAKGDRGETGPAGPPGAP--------- 1048 Query: 1023 LNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPG 1082 G G G G+ G++G+ +GP G G GP G +G GPQGP G G Sbjct: 1049 --GAPGAPGPVGPAGKSGDRGE-------TGPAGPAGPVGPVGARGPA--GPQGPRGDKG 1097 Query: 1083 LPGPPG----------FGRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSR 1132 G G G G PGPPG PG GP G A GP GPPG G PG Sbjct: 1098 ETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPA----GPRGPPGSAGAPGKD 1153 Query: 1133 NL 1134 L Sbjct: 1154 GL 1155 Score = 311 bits (798), Expect = 2e-84 Identities = 219/577 (37%), Positives = 251/577 (43%), Gaps = 82/577 (14%) Query: 569 DAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPG 628 D + PG P G P +E + V GD RGP GP GPPG Sbjct: 76 DETKNCPGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGP-----RGPRGPAGPPG 130 Query: 629 LPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDG-ATGLPGMKGEKGARGPN 687 GIPG+PG GPPG PG GP G G P+ G D +TG + G G GP Sbjct: 131 RDGIPGQPGLP---GPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPR 187 Query: 688 GSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGS 747 G G G PG +G GPPG+ G+ G G MGP GPPGPPG G D +G Sbjct: 188 GLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNG----------DDGEAGK 237 Query: 748 TQLLNEPKLSRPTAAIGLKGEKGDRGPKGERG---MDGAS-IVGPPGPRGPPGHIKVLSN 803 E P A GL G G G KG RG +DGA GP GP+G PG Sbjct: 238 PGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGA 297 Query: 804 SLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGE 863 G P GP G G G G GP GP G G PGFPG G +GE G Sbjct: 298 PGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGP 357 Query: 864 PGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTK 923 G G +G G+ G PGP GP G G G G G+PG G NG G Sbjct: 358 QGP-----------RGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIA 406 Query: 924 GDPGVI-MQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITF 982 G PG +GP G GP GPPGP G ++ PG+P Sbjct: 407 GAPGFPGARGPSGPQGPGGPPGPKG----------------------NSGEPGAPGSKGD 444 Query: 983 HGVKGEKGSWGL---PGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEK 1039 G KGE G G+ PG GE+G +GA+G PGP L G G++G G + Sbjct: 445 TGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGP-----------TGLPGPPGERGGPGSR 493 Query: 1040 GEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPGF-GRPGDPGPP 1098 G G +G GP G G+PGPAG KG G G PG GLPG G G PG PGP Sbjct: 494 GFPG-ADGVAGPKGPAGERGSPGPAGPKGSP--GEAGRPGEAGLPGAKGLTGSPGSPGPD 550 Query: 1099 GPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNLV 1135 G GPPGP G PGPPG PG G ++ Sbjct: 551 GKTGPPGP-------AGQDGRPGPPGPPGARGQAGVM 580 Score = 189 bits (481), Expect = 1e-47 Identities = 140/390 (35%), Positives = 158/390 (40%), Gaps = 112/390 (28%) Query: 770 GDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDG 829 G GPKG+ GP GPRGP GPPG DG Sbjct: 109 GVEGPKGD--------TGPRGPRGP---------------------------AGPPGRDG 133 Query: 830 LPGLPGFPGPRGPKGDTGLPGF-----PGLKGEQGEKGEPGAILTEDIPLERLMGKKGEP 884 +PG PG PGP GP G G PG P L EK G + + G +G P Sbjct: 134 IPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPS---GPRGLP 190 Query: 885 GMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPG 944 G GAPGP G +GPPG GE G G G G G G GD G G PG PG GPPG Sbjct: 191 GPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEA--GKPGRPGERGPPG 248 Query: 945 PPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQ 1004 P GA G P G+KG +G GL G+KG+ G Sbjct: 249 PQGA-------------------------RGLPGTAGLPGMKGHRGFSGLDGAKGDAGPA 283 Query: 1005 GAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPA 1064 G +G PG P GENG G G +G + G G PG PGPA Sbjct: 284 GPKGEPGSP--------------GENGAPGQMGPRG----------LPGERGRPGAPGPA 319 Query: 1065 GQKG-ETVVGPQGPPGAPGLPGPPGF----GRPGDPGPPGP------------PGPPGPP 1107 G +G + G GPPG G GPPGF G G+ GP GP PGPPGP Sbjct: 320 GARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPA 379 Query: 1108 AILGAAVALPGPPGPPGQPGLPGSRNLVTA 1137 G A PG G PG G G+ + A Sbjct: 380 GAAGPA-GNPGADGQPGAKGANGAPGIAGA 408 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 367 bits (941), Expect = e-101 Identities = 260/662 (39%), Positives = 304/662 (45%), Gaps = 79/662 (11%) Query: 519 ITAGGEESGSPPPDGP------PLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGE 572 I +E P P+ P P P AP R P + G KG GP G G G+ Sbjct: 65 IICDDQELDCPNPEIPFGECCAVCPQPPTAPTR--PPNGQGPQGPKGDPGPPGIPGRNGD 122 Query: 573 E-LPGPPEPSGPVGPTAGAEAEGSGLGWGS------DVGSGS--GDLVGSEQLLRGPPGP 623 +PG P G GP E+ +G S DV SG G L G GPPGP Sbjct: 123 PGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPA-GPPGP 181 Query: 624 PGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPP---GPEGQPGVDGATGLPGMKGE 680 PGPPG G PG PG+ + GPPG PG+ GP+G PGPP GP G G DG +G PG GE Sbjct: 182 PGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGE 241 Query: 681 KGARGPNGSVGEKGDP---------------GNRGLPGPPGKKGQAGPPGVMGPPGPPGP 725 +G GP G G G P G +G G PG KG+ G PG G PGP GP Sbjct: 242 RGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGP 301 Query: 726 PGPPG----PGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMD 781 G PG PG G +G+ + +P P G G G +G G G Sbjct: 302 RGAPGERGRPGLPGAAGARGNDGARGSD--GQPGPPGPPGTAGFPGSPGAKGEVGPAGSP 359 Query: 782 GASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRG 841 G++ G PG RG PG ++ G + P G GP G+PG PG G RG Sbjct: 360 GSN--GAPGQRGEPG---PQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARG 414 Query: 842 PKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGH 901 P G G G PGL+G GE G+ GA KGEPG G G G G PG Sbjct: 415 PPGPAGANGAPGLRGGAGEPGKNGA--------------KGEPGPRGERGEAGIPGVPGA 460 Query: 902 KGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPG--AVINIKGAIFPI 959 KGE G G PG PG NGL G G+ +G PG GP GP G PG +GA P Sbjct: 461 KGEDGKDGSPGEPGANGLPGAAGE-----RGAPGFRGPAGPNGIPGEKGPAGERGAPGPA 515 Query: 960 PVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGP--PLDLA 1017 R P PG P + G G GS G PG G +G+ G GPPGP P Sbjct: 516 GPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQP 575 Query: 1018 YLRHF-----LNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGET-V 1071 + F + G+NG++G G G +G G +GP G PG GP G KG+T Sbjct: 576 GVMGFPGPKGNDGAPGKNGERGGPGGPGPQGP-PGKNGETGPQGPPGPTGPGGDKGDTGP 634 Query: 1072 VGPQGPPGAPGLPGPPG-FGRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPG 1130 GPQG G PG GPPG G+PG+PGP G G PG P G A A PG GPPG G PG Sbjct: 635 PGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGA-PGERGPPGLAGAPG 693 Query: 1131 SR 1132 R Sbjct: 694 LR 695 Score = 367 bits (941), Expect = e-101 Identities = 265/679 (39%), Positives = 299/679 (44%), Gaps = 116/679 (17%) Query: 525 ESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEEL----PGPPEP 580 ESG P P GP P R G+ G GPKG G G+ PG P P Sbjct: 559 ESGRPGPPGPSGP--------------RGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGP 604 Query: 581 SGPVGPTA--GAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGT 638 GP G G + G G D G Q L+G PG GPPG G PG+PG Sbjct: 605 QGPPGKNGETGPQGPPGPTGPGGDKGDTGPP---GPQGLQGLPGTGGPPGENGKPGEPGP 661 Query: 639 DVFMGPPGSPGEDGPAGEPG------------------PPGPEG---------QPGVDGA 671 G PG+PG G AG PG PPGPEG PG G Sbjct: 662 KGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGT 721 Query: 672 TGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGP 731 GL GM GE+G G G G+KG+PG G G PGK G GP G +GPPGP G PG G Sbjct: 722 PGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGE 781 Query: 732 GCTMGL-GFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGAS------ 784 G GL G GS + E P G G+ G+ G KGERG G Sbjct: 782 GGAPGLPGIAGPRGSPGER--GETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPP 839 Query: 785 -IVGPPG---PRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPG------LP 834 + GPPG P GPPG V G F L GPPG +G PG P Sbjct: 840 GVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSP 899 Query: 835 GFPGPRGPKGDTGLPGFPGLKG------EQGEKGEPGAILTEDIP----LERLMGKKGEP 884 G GP GP G+TG PG PG+ G + GEKG PGA P + + G +G Sbjct: 900 GKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLA 959 Query: 885 GMHGAPGPMGPKGPPGHKGEFGLPGR---------PGRPGLNGLKGTKGDPGVIMQGPPG 935 G G PGP G GP G KGE G PG PG GL GL GT G+PG G PG Sbjct: 960 GPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPG--RDGNPG 1017 Query: 936 LPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLP 995 G PG G PG + P P HPG P + G G++G G Sbjct: 1018 SDGLPGRDGSPGGKGDRGENGSP-------GAPGAPGHPGPPGPVGPAGKSGDRGESGPA 1070 Query: 996 GSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPP 1055 G G G G++G PGP +G GDKG GE+G G I G G P Sbjct: 1071 GPAGAPGPAGSRGAPGP--------------QGPRGDKGETGERGAAG-IKGHRGFPGNP 1115 Query: 1056 GLPGNPGPAGQKGET-VVGPQGPPGAPGLPGPPGF-GRPGDPGPPGPPGPPGPPAILGA- 1112 G PG+PGPAGQ+G GP GP G G GPPG G G PGP GPPGP G G+ Sbjct: 1116 GAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSE 1175 Query: 1113 -AVALPGPPGPPGQPGLPG 1130 + PG PGPPG PG PG Sbjct: 1176 GSPGHPGQPGPPGPPGAPG 1194 Score = 356 bits (914), Expect = 8e-98 Identities = 268/680 (39%), Positives = 304/680 (44%), Gaps = 105/680 (15%) Query: 527 GSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSGPVGP 586 G P P GPP +P + VG G G G G GE PGP +G GP Sbjct: 330 GQPGPPGPPGTAGFPG-----SPGAKGEVGPAGSPGSNGAPGQRGE--PGPQGHAGAQGP 382 Query: 587 TAGAEAEGSGLGWGSDVGSGSGDLVGSEQLL--RGPPGPPGPPGLPGI---PGKPGTDVF 641 GS G G G + G+ L+ RGPPGP G G PG+ G+PG + Sbjct: 383 PGPPGINGSPGGKGE---MGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGA 439 Query: 642 MGPPGSPGEDGPAGEPGPPGPEGQ------PGVDGATGLPGMKGEKGA------RGPNGS 689 G PG GE G AG PG PG +G+ PG GA GLPG GE+GA GPNG Sbjct: 440 KGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGI 499 Query: 690 VGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPG-PGCTMGLGFEDTEGS-GS 747 GEKG G RG PGP G +G AG PG G PG PG G PG PG G G + G GS Sbjct: 500 PGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPG---GPGSDGKPGPPGS 556 Query: 748 TQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIV----GPPGPRGPPG-HIKVLS 802 P P+ G G G GPKG G G + G PGP+GPPG + + Sbjct: 557 QGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGP 616 Query: 803 NSLINITHGFMNFSDIPELVGPPGPDGLPGLPGF---------PGPRGPKGDTGLPGFPG 853 T + D GPPGP GL GLPG PG GPKGD G PG PG Sbjct: 617 QGPPGPTGPGGDKGD----TGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPG 672 Query: 854 LKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGR 913 KG+ G GE G P L G G PG G G GP GPPG G GL G PG Sbjct: 673 GKGDAGAPGERGPPGLAGAP--GLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGE 730 Query: 914 ------PGLNGLKGTKGDPGVI-------MQGPPGLPGPPGPPGPPG--------AVINI 952 PG G KG G PG +GP G GPPGP G PG + I Sbjct: 731 RGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGI 790 Query: 953 KGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGP 1012 G R P PG+P +G G KG G PG KGE G G GPPG Sbjct: 791 AGPRGSPGERGETGPPGPAGFPGAPGQ---NGEPGGKGERGAPGEKGEGGPPGVAGPPGG 847 Query: 1013 PLDLAYLRHFLNNLKGENGDKGFKGEKGEKGD-----INGSFLMSGPPGLPGNPGPAGQK 1067 + G G +G KGE+G G G+ + GPPG GNPGP G Sbjct: 848 -----------SGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPS 896 Query: 1068 GETVV-GPQGP------PGAPGLPGPPG-FGRPGDPGPPGPPGPPGPPAILG-----AAV 1114 G GP GP PG+PG+ GP G G+PG+ G PG GPPG P LG A Sbjct: 897 GSPGKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGAR 956 Query: 1115 ALPGPPGPPGQPGLPGSRNL 1134 L GPPG PG G PG + + Sbjct: 957 GLAGPPGMPGPRGSPGPQGV 976 Score = 352 bits (903), Expect = 1e-96 Identities = 250/649 (38%), Positives = 283/649 (43%), Gaps = 107/649 (16%) Query: 556 GMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTA-----------GAEAEGSGLGWGSDVG 604 G KG+ GP+GE+G+AG +PG P G G GA E G+ G Sbjct: 438 GAKGEPGPRGERGEAG--IPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAG 495 Query: 605 SGSGDLVGSEQLLRGPPGPPGP---------------PGLPGIPGKPGTDVFMGPPGSPG 649 RG PGP GP PG+ G+PG PG G PG PG Sbjct: 496 PNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPG 555 Query: 650 EDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKG 709 G +G PGPPGP G G G G PG KG GA G N GE+G PG G GPPGK G Sbjct: 556 SQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKN---GERGGPGGPGPQGPPGKNG 612 Query: 710 QAGPPGVMGPPGPPGPPGPPGPGCTMGL-GFEDTEG-SGSTQLLNEPKLSRPTAAIGLKG 767 + GP G GP GP G G GP GL G T G G EP A G G Sbjct: 613 ETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPG 672 Query: 768 EKGDRGPKGERGMDGAS-------IVGPPGPR------GPPGHIKVLSNSLINITHGFMN 814 KGD G GERG G + GPPGP GPPG + G Sbjct: 673 GKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERG 732 Query: 815 FSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPL 874 P G G G PG G PG GP+G TG G PG G+ G+KGE GA L Sbjct: 733 GLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGA-----PGL 787 Query: 875 ERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPP 934 + G +G PG G GP GP G PG G+ G PG G G G KG G PGV GPP Sbjct: 788 PGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGV--AGPP 845 Query: 935 GLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITF---HGVKGEKGS 991 G GP GPPGP G +KG + PG P F G+ G GS Sbjct: 846 GGSGPAGPPGPQG----VKG---------------ERGSPGGPGAAGFPGARGLPGPPGS 886 Query: 992 WGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKG-------- 1043 G PG G G G GPPGP + + G GD G GEKG G Sbjct: 887 NGNPGPPGPSGSPGKDGPPGPAGNTG--APGSPGVSGPKGDAGQPGEKGSPGAQGPPGAP 944 Query: 1044 ------DINGSFLMSGPPGLP---GNPGPAGQKGET-------VVGPQGPPGAPGLPGPP 1087 I G+ ++GPPG+P G+PGP G KGE+ + G +GPPG GLPG Sbjct: 945 GPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLA 1004 Query: 1088 GF----GRPGDPGPPGPPGPPGPPAILG--AAVALPGPPGPPGQPGLPG 1130 G GR G+PG G PG G P G PG PG PG PG PG Sbjct: 1005 GTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPG 1053 Score = 352 bits (902), Expect = 2e-96 Identities = 269/693 (38%), Positives = 304/693 (43%), Gaps = 126/693 (18%) Query: 525 ESGSPPPDG--PPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEE----LPGPP 578 E G P P G P +P P + H G G+ G KGE G G + LPG Sbjct: 241 ERGLPGPPGIKGPAGIPGF-------PGMKGHRGFDGRNGEKGETGAPGLKGENGLPGEN 293 Query: 579 EPSGPVGPTAGAEAEGSGLGWGSDVGS-GSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPG 637 GP+GP GA E G G+ G+ GS+ G PGPPGPPG G PG PG Sbjct: 294 GAPGPMGPR-GAPGERGRPGLPGAAGARGNDGARGSD----GQPGPPGPPGTAGFPGSPG 348 Query: 638 TDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPG 697 +GP GSPG +G G+ G PGP+G G G G PG+ G G +G G G G PG Sbjct: 349 AKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPG 408 Query: 698 NRGLPGPPGKKGQAGPPGVMGPPGPP------GPPGPPG-------PGCTMGLGFEDTEG 744 G GPPG G G PG+ G G P G PGP G PG G + +G Sbjct: 409 LMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDG 468 Query: 745 SGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDG----ASIVGPPGPRGP------ 794 S EP + A G +G G RGP G G+ G A G PGP GP Sbjct: 469 SP-----GEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGE 523 Query: 795 PGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGL 854 PG V + G GPPG G G PG PGP GP+G G+ GFPG Sbjct: 524 PGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGP 583 Query: 855 K------GEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGP------KGPPGHK 902 K G+ GE+G PG + P GK GE G G PGP GP GPPG + Sbjct: 584 KGNDGAPGKNGERGGPGGPGPQGPP-----GKNGETGPQGPPGPTGPGGDKGDTGPPGPQ 638 Query: 903 GEFGLPGRPGRPGLNGL---KGTKGDPGVI-------------MQGPPGLPGPP------ 940 G GLPG G PG NG G KGD G +GPPGL G P Sbjct: 639 GLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGA 698 Query: 941 GPPGPPGAVINIKGAIFPIPVRPHCK-------MPVDTAHPGSPELITFHGVKGEKGSWG 993 GPPGP G KGA P P P MP + GSP G G G+ G Sbjct: 699 GPPGPEGG----KGAAGP-PGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADG 753 Query: 994 LPGSKGEKGDQGAQGPPGP---PLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFL 1050 +PG G +G G GPPGP P D KGE G G G G +G G Sbjct: 754 VPGKDGPRGPTGPIGPPGPAGQPGD-----------KGEGGAPGLPGIAGPRGS-PGERG 801 Query: 1051 MSGPPGLPGNPGPAGQKGET-VVGPQGPPGAPGLPGPPGF-GRPGDPGPPGPPGP----- 1103 +GPPG G PG GQ GE G +G PG G GPPG G PG GP GPPGP Sbjct: 802 ETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKG 861 Query: 1104 ----PGPPAILG--AAVALPGPPGPPGQPGLPG 1130 PG P G A LPGPPG G PG PG Sbjct: 862 ERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPG 894 Score = 350 bits (897), Expect = 7e-96 Identities = 255/670 (38%), Positives = 297/670 (44%), Gaps = 153/670 (22%) Query: 526 SGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSGPVG 585 +G P DG P P P G G+ GP G +G++G PGPP PSGP G Sbjct: 521 AGEPGRDGVP-----GGPGMRGMPGSPGGPGSDGKPGPPGSQGESGR--PGPPGPSGPRG 573 Query: 586 PTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPP 645 + +G+ G+ E RG PG PGP G PG G+ G GPP Sbjct: 574 -------QPGVMGFPGPKGNDGAPGKNGE---RGGPGGPGPQGPPGKNGETGPQ---GPP 620 Query: 646 GSPGEDGPAGEPGPPGPEG---------QPGVDGATGLPGMKGEKGARGPNGSVGEKGDP 696 G G G G+ GPPGP+G PG +G G PG KG+ GA G G G+ G P Sbjct: 621 GPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAP 680 Query: 697 GNRGLPG---PPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNE 753 G RG PG PG +G AGPPG G G GPPGPPG T GL E G Sbjct: 681 GERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGG------- 733 Query: 754 PKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFM 813 +G G KGD+G G G DG + G GPRGP G I Sbjct: 734 ---------LGSPGPKGDKGEPGGPGADG--VPGKDGPRGPTGPI--------------- 767 Query: 814 NFSDIPELVGPPGP---------DGLPGLPGFPGPRGP---KGDTGLPGFPGLKGEQGEK 861 GPPGP G PGLPG GPRG +G+TG PG G G G+ Sbjct: 768 ---------GPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQN 818 Query: 862 GEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKG 921 GEPG P E+ G+ G PG+ G PG GP GPPG +G G G PG PG G G Sbjct: 819 GEPGGKGERGAPGEK--GEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPG 876 Query: 922 TKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPV-DTAHPGSPELI 980 +G PG PPG G PGPPGP G+ P + P +T PGSP Sbjct: 877 ARGLPG-----PPGSNGNPGPPGPSGS-----------PGKDGPPGPAGNTGAPGSP--- 917 Query: 981 TFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHF--------LNNLKGENGD 1032 GV G KG G PG KG G QG G PGP L +A + + +G G Sbjct: 918 ---GVSGPKGDAGQPGEKGSPGAQGPPGAPGP-LGIAGITGARGLAGPPGMPGPRGSPGP 973 Query: 1033 KGFKGEKGEKG--DINGSFLMSGPPGLPG------------------------NPGPAGQ 1066 +G KGE G+ G ++G GP GLPG +PG G Sbjct: 974 QGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGD 1033 Query: 1067 KGETVVGPQGPPGAPGLPGPPG----FGRPGDPGPPGPPGPPGPPAILGAAVALPGPPGP 1122 +GE G G PGAPG PGPPG G+ GD G GP GP G P G+ A PGP GP Sbjct: 1034 RGEN--GSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGA-PGPQGP 1090 Query: 1123 PGQPGLPGSR 1132 G G G R Sbjct: 1091 RGDKGETGER 1100 Score = 278 bits (712), Expect = 2e-74 Identities = 208/566 (36%), Positives = 238/566 (42%), Gaps = 97/566 (17%) Query: 503 PGDEEDLAAATTEEP--LITAGGEESGSPPPD--------GPPLPLPTVA--PERWITPA 550 PG + D A P L A G G+ PP GPP P P A P P Sbjct: 671 PGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGP-PGAAGTPGLQGMPG 729 Query: 551 QREHVGMKGQAGPKGEKGDAGEE----LPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSG 606 +R +G G G KGE G G + GP P+GP+GP A G G+ G Sbjct: 730 ERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPG 789 Query: 607 SGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQP 666 GS RG GPPGP G PG PG+ G G G+PGE G E GPPG G P Sbjct: 790 IAGPRGSPGE-RGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKG---EGGPPGVAGPP 845 Query: 667 GVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPP 726 G G G PG +G KG RG G G G PG RGLPGPPG G GPPG G PG GPP Sbjct: 846 GGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPP 905 Query: 727 GPPG-------------------PGCTMGLGFEDTEGS----------GSTQLLNEPKLS 757 GP G PG G + G+ G+ L P + Sbjct: 906 GPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMP 965 Query: 758 RPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSD 817 P + G +G KG+ G G G+ G GPPGP+G PG + Sbjct: 966 GPRGSPGPQGVKGESGKPGANGLSGER--GPPGPQGLPG---------------LAGTAG 1008 Query: 818 IPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPG-AILTEDIPLER 876 P G PG DGLPG G PG +G +G+ G PG PG G G G G A + D Sbjct: 1009 EPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESG 1068 Query: 877 LMGKKGEPG---MHGAPGPMGPKGPPGHKGEFGLPGR------PGRPGLNGLKGTKGDPG 927 G G PG GAPGP GP+G G GE G G PG PG G G G G Sbjct: 1069 PAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQG 1128 Query: 928 VI-MQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVK 986 I GP G GP GP GPPG + HPG G + Sbjct: 1129 AIGSPGPAGPRGPVGPSGPPG-------------------KDGTSGHPGPIGPPGPRGNR 1169 Query: 987 GEKGSWGLPGSKGEKGDQGAQGPPGP 1012 GE+GS G PG G+ G G G PGP Sbjct: 1170 GERGSEGSPGHPGQPGPPGPPGAPGP 1195 Score = 260 bits (665), Expect = 6e-69 Identities = 212/606 (34%), Positives = 246/606 (40%), Gaps = 98/606 (16%) Query: 382 TGGPTLSMSTENPEEGVTPGPDNEERLAATAAGEAEALASMPGEVEASGVAPGELDLSMS 441 TGGP EN + G PGP + G+ +A A PGE G+A G L Sbjct: 646 TGGPP----GENGKPG-EPGPKGDAGAPGAPGGKGDAGA--PGERGPPGLA-GAPGLRGG 697 Query: 442 AQSLGEEATVGPSSEDSLTTAAAATEVSLSTFE-----------------DEEASGVP-T 483 A G E G + AA + E A GVP Sbjct: 698 AGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGK 757 Query: 484 DGLAPLTATMAPERAVTSGPGDEEDLAAATTEEPLITAGGEESGSPPPDGPPLPLPTVAP 543 DG T + P PGD+ + A P I G GPP P Sbjct: 758 DGPRGPTGPIGPP-GPAGQPGDKGEGGAPGL--PGIAGPRGSPGERGETGPPGPAGFPG- 813 Query: 544 ERWITPAQREHVGMKGQAGPKGEKGDAGEE-LPGPPEPSGPVGPTAGAEAEGSGLGWGSD 602 P Q G KG+ G GEKG+ G + GPP SGP GP +G GS Sbjct: 814 ----APGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGER---GSP 866 Query: 603 VGSGSGDLVGSEQL-----LRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEP 657 G G+ G+ L G PGPPGP G PG G PG G PGSPG GP G+ Sbjct: 867 GGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPGVSGPKGDA 926 Query: 658 GPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVM 717 G PG +G PG G G PG G G G G G G PG RG PGP G KG++G PG Sbjct: 927 GQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGAN 986 Query: 718 GPPGPPGPPGPPG-PGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKG 776 G G GPPGP G PG G +G+ + GL G G G KG Sbjct: 987 GLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSD--------------GLPGRDGSPGGKG 1032 Query: 777 ERGMDGA-SIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPG 835 +RG +G+ G PG GPPG + S G S G PGP G G PG Sbjct: 1033 DRGENGSPGAPGAPGHPGPPGPVGPAGKS------GDRGESGPAGPAGAPGPAGSRGAPG 1086 Query: 836 FPGPRGPKGDTG------------LPGFPGLKGEQGEKGEPGAILTEDIPLER----LMG 879 GPRG KG+TG PG PG G G G+ GAI + R G Sbjct: 1087 PQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSG 1146 Query: 880 KKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGP 939 G+ G G PGP+GP GP G++GE G G PG P G PG PGP Sbjct: 1147 PPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHP-----------------GQPGPPGP 1189 Query: 940 PGPPGP 945 PG PGP Sbjct: 1190 PGAPGP 1195 Score = 169 bits (427), Expect = 2e-41 Identities = 122/332 (36%), Positives = 135/332 (40%), Gaps = 92/332 (27%) Query: 819 PELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPL---- 874 P GP GP G PG PG PG G PG PG G G G PG + E P Sbjct: 99 PNGQGPQGPKGDPGPPGIPGRNGD------PGIPGQPGSPGSPGPPG--ICESCPTGPQN 150 Query: 875 -----ERLMGKKGEP--GMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPG 927 + K G G+ G PGP GP GPPG G G PG PG PG G Sbjct: 151 YSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQG--------- 201 Query: 928 VIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKG 987 G PG GP GPPGPPGA+ P P G G Sbjct: 202 --PPGEPGQAGPSGPPGPPGAI-----------------------GPSGPA-----GKDG 231 Query: 988 EKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDING 1047 E G G PG +G G G +GP G P G G +GF G GEKG+ Sbjct: 232 ESGRPGRPGERGLPGPPGIKGPAGIP-----------GFPGMKGHRGFDGRNGEKGE--- 277 Query: 1048 SFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPGF----GRPGDPGPPGPPGP 1103 +G PGL G G G+ G GP GP GAPG G PG G G+ G G G Sbjct: 278 ----TGAPGLKGENGLPGENGAP--GPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQ 331 Query: 1104 PGPPAILGAAVALPGPPGPPGQPGLPGSRNLV 1135 PGPP GPPG G PG PG++ V Sbjct: 332 PGPP----------GPPGTAGFPGSPGAKGEV 353 Score = 48.9 bits (115), Expect = 3e-05 Identities = 33/98 (33%), Positives = 42/98 (42%), Gaps = 11/98 (11%) Query: 527 GSPPPDGPPLPL-PTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEE-------LPGPP 578 GSP P GP P+ P+ P + T H G G GP+G +G+ G E PGPP Sbjct: 1131 GSPGPAGPRGPVGPSGPPGKDGTSG---HPGPIGPPGPRGNRGERGSEGSPGHPGQPGPP 1187 Query: 579 EPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQL 616 P G GP G + G G + G G E + Sbjct: 1188 GPPGAPGPCCGGVGAAAIAGIGGEKAGGFAPYYGDEPM 1225 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 366 bits (939), Expect = e-101 Identities = 249/640 (38%), Positives = 297/640 (46%), Gaps = 62/640 (9%) Query: 523 GEESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSG 582 G + S P P P + P + VG G GP G G+ GE+ GPP P+G Sbjct: 618 GPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQ--GPPGPTG 675 Query: 583 PVGPTAGAEAEGSGLGWGSDVGSGSGDLVG--SEQLLRGPPGPPGPPGLPGIPGKPGTDV 640 G G G G G VG + RG PG G PG+ G+PG+ G Sbjct: 676 FQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAG 735 Query: 641 FMGPPGSPGEDGPAGEPG---PPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPG 697 GP G G GP+G PG PPG +G PG G G PG KG++G G G+ G G+ G Sbjct: 736 GHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDG 795 Query: 698 NRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLS 757 RGLPGP G G AGP G G PGP G GPPG G E+ G T + Sbjct: 796 ARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGEN----GPTGAVGFAGPQ 851 Query: 758 RPTAAIGLKGEKGDRGPKGERGMDGAS-IVGPPGPRGPPGHIKVLSNSLINITHGFMNFS 816 P G+KGE G+ G KG+ G G + G PGP GP G + G F Sbjct: 852 GPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFP 911 Query: 817 DIPELVGPPGPDGLPGLPG---FPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIP 873 VGPPGP G PG G PG GP G G PG G G++G G PG Sbjct: 912 GSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGG------- 964 Query: 874 LERLMGKKGEPGMHGAPGPMGPKGP------------PGHKGEFGLPG------RPGRPG 915 G KG+PG G PGP GP GP PG +GE G+PG PG+ G Sbjct: 965 ----PGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVG 1020 Query: 916 LNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVIN--IKGAIFPIPVRPHCKMPVDTAH 973 G G KG PG + GPPG GP G PGP G N G + R D Sbjct: 1021 PTGATGDKGPPGPV--GPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERG------DRGD 1072 Query: 974 PGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDK 1033 PG L G G G G PG G++GD G++GP GPP + L +G GDK Sbjct: 1073 PGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAG--KRGLPGPQGPRGDK 1130 Query: 1034 GFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGET-VVGPQGPPGAPGLPGPPGFGRP 1092 G G++G++G G +G GLPG PGP G++G + GP GP G PG GP G + Sbjct: 1131 GDHGDRGDRGQ-KGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSG--KE 1187 Query: 1093 GDPGPPGPPGPPGPPAILGAA--VALPGPPGPPGQPGLPG 1130 G+PGP GP GPPG +G A PG PGPPG PG PG Sbjct: 1188 GNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPG 1227 Score = 350 bits (899), Expect = 4e-96 Identities = 281/776 (36%), Positives = 320/776 (41%), Gaps = 128/776 (16%) Query: 384 GPTLSMSTENPEEGVTPGPDNEERLAATAAGEAEALASMPGE--------VEASGVAPGE 435 GPT M P G P RL A MPG+ + S PG Sbjct: 324 GPTGPMGAMGPL-GPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGN 382 Query: 436 LDLSMSAQSLGEEATVGPSSEDSLTTAAAATEVSLSTFEDEEASGVPTDGLAPLTATMAP 495 + A G GP + T G P P+ + P Sbjct: 383 PGMKGEAGPTGARGPEGPQGQRGET-------------------GPP----GPVGSPGLP 419 Query: 496 ERAVTSG-PGDEEDLAAATTEEPLITAGGEESGSPPPDGPPLPLPTVAPERWITPAQREH 554 T G PG + + T P +AG GSP P G P P Sbjct: 420 GAIGTDGTPGAKGPTGSPGTSGPPGSAG--PPGSPGPQGSTGPQGIRGQ-----PGDPGV 472 Query: 555 VGMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSE 614 G KG+AGPKGE PGP GP+GP G E + G VG Sbjct: 473 PGFKGEAGPKGE--------PGPHGIQGPIGPP-GEEGKRGPRGDPGTVG---------- 513 Query: 615 QLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGL 674 PPGP G G PG G PG+D GP G+ GE GP G GP G +G PG G GL Sbjct: 514 -----PPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEPGL 568 Query: 675 PGMKG---EKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPG- 730 PG +G G +GP G +G G PG G PGPPG G G PG MG PGP G G PG Sbjct: 569 PGARGLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGK 628 Query: 731 PGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPG 790 PG G G+ E S P GL GE+G++GP G G G PG Sbjct: 629 PGEAGNAGVPGQRGAPGKD--GEVGPSGPVGPPGLAGERGEQGPPGPTGFQGL-----PG 681 Query: 791 PRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPG 850 P GPPG G PG G+PG PG GP GP+G+ G PG Sbjct: 682 PPGPPGE------------------------GGKPGDQGVPGDPGAVGPLGPRGERGNPG 717 Query: 851 F---PGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGL 907 PG+ G GEKG G + G KG PG G PG GP G G GE G+ Sbjct: 718 ERGEPGITGLPGEKGMAGGHGPD--------GPKGSPGPSGTPGDTGPPGLQGMPGERGI 769 Query: 908 PGRPGRPGLNGLKGTKGDPGVI-MQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCK 966 G PG G G G KG G G GLPGP GPPGP G KG P R Sbjct: 770 AGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPT-GEKGEPGP---RGLVG 825 Query: 967 MPVDTAHPGS------PELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPP-LDLAYL 1019 P +PGS + F G +G G G+ G GE G +G G PGP L + Sbjct: 826 PPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPG 885 Query: 1020 RHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPG 1079 H N + G G +G +G G G GS GPPG G PGPAG GE G +GPPG Sbjct: 886 PHGPNGVPGLKGGRGTQGPPGATG-FPGSAGRVGPPGPAGAPGPAGPLGEP--GKEGPPG 942 Query: 1080 APGLPGPPGFGRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNLV 1135 G PG GR GD GP GPPG PG G PGP GPPG G G R +V Sbjct: 943 LRGDPG--SHGRVGDRGPAGPPGGPGDKGDPGED-GQPGPDGPPGPAGTTGQRGIV 995 Score = 348 bits (892), Expect = 3e-95 Identities = 246/648 (37%), Positives = 299/648 (46%), Gaps = 108/648 (16%) Query: 527 GSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEE-LPGPPEPSGPVG 585 GS GP P+ + P R G +G+ GP+G G G +PG P P GP+G Sbjct: 318 GSKGEAGPTGPMGAMGPL-----GPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLG 372 Query: 586 PTAGAEAEGS-GL-GWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMG 643 + G+ G+ G G+ + ++ GPPGP G PGLPG G GT G Sbjct: 373 IPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAKG 432 Query: 644 PPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLP- 702 P GSPG GP G GPPG G G G G+ G G+ G G G G KG+PG G+ Sbjct: 433 PTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQG 492 Query: 703 --GPPGKKGQAGP---PGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLS 757 GPPG++G+ GP PG +GPPGP G G PG GF ++G L PK + Sbjct: 493 PIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPG-----NRGFPGSDG------LPGPKGA 541 Query: 758 R----PTAAIGLKGEKGDRGPKGERGMDGA-SIVGPPGPRGPPGHIKVLSNSLINITHGF 812 + P + G KG +GD G GE G+ GA + G PG +GP G + L Sbjct: 542 QGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPL----------- 590 Query: 813 MNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDI 872 G PG DG PG PG G RG G GL PG KG G+ G+PG + Sbjct: 591 ----------GAPGEDGRPGPPGSIGIRGQPGSMGL---PGPKGSSGDPGKPGEAGNAGV 637 Query: 873 PLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQG 932 P G++G PG G GP GP GPPG GE G G PG G GL G G P G Sbjct: 638 P-----GQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPP-----G 687 Query: 933 PPGLPGPPGPPGPPGAVINIKGAIFPIPVRPH---CKMPVDTAHPGSPELITFHGVKGEK 989 G PG G PG PGAV G + P R + P T PG + HG G K Sbjct: 688 EGGKPGDQGVPGDPGAV----GPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPK 743 Query: 990 GSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDI--NG 1047 GS G G+ G+ G G QG PG + G GD+G GEKG +G +G Sbjct: 744 GSPGPSGTPGDTGPPGLQGMPG--------ERGIAGTPGPKGDRGGIGEKGAEGTAGNDG 795 Query: 1048 SFLMSGPPGLPGNPGPAGQKGET----VVGP------------QGPPGAPGLPGPPG--- 1088 + + GP G PG GP G+KGE +VGP GP GA G GP G Sbjct: 796 ARGLPGPLGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDG 855 Query: 1089 ----FGRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSR 1132 G PG+PG G G PGP + G+ PGP GP G PGL G R Sbjct: 856 QPGVKGEPGEPGQKGDAGSPGPQGLAGS----PGPHGPNGVPGLKGGR 899 Score = 343 bits (881), Expect = 5e-94 Identities = 262/668 (39%), Positives = 312/668 (46%), Gaps = 123/668 (18%) Query: 527 GSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEE-------LPGPP- 578 G P P GPP + R G KG+ GP+G +G GE PGPP Sbjct: 129 GRPGPAGPPG-----------SQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPG 177 Query: 579 EPS--GPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKP 636 PS GP G + A+ +GL S +GS G + GS GP GP GP GL G G Sbjct: 178 HPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSV----GPVGPRGPQGLQGQQGGA 233 Query: 637 GTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDP 696 G GPPG PG+ GP G G GPEG PG G G PG G G G GS G +G P Sbjct: 234 GP---TGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFP 290 Query: 697 GNRGLP------------------GPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMG-L 737 G GLP G PG KG+AGP G MG GP GP G PG +G Sbjct: 291 GAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQ 350 Query: 738 GFEDTEGS-------GSTQLLNEPKLSRPTAAIGLKGEKGD---RGPKGERGMDGASIVG 787 G G+ G L P S G+KGE G RGP+G +G G + G Sbjct: 351 GAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGET--G 408 Query: 788 PPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPP---GPDGLPGLPGFPGPRGPKG 844 PPGP G PG + + T G + P GPP GP G PG G GP+G +G Sbjct: 409 PPGPVGSPGLPGAIGT---DGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRG 465 Query: 845 DTGLPGFPGLKGEQGEKGEPGAILTEDIPL-----ERLMGKKGEPGMHGAPGPMGPKGPP 899 G PG PG KGE G KGEPG + P+ E G +G+PG G PGP+G +G P Sbjct: 466 QPGDPGVPGFKGEAGPKGEPGPHGIQG-PIGPPGEEGKRGPRGDPGTVGPPGPVGERGAP 524 Query: 900 GHKGEFGLPGRPGRPGL---------NGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVI 950 G++G G G PG G +G KG++GDPG G PGLPG G G PG V Sbjct: 525 GNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPG--RPGEPGLPGARGLTGNPG-VQ 581 Query: 951 NIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPP 1010 +G + P+ P + PG P I G++G+ GS GLPG KG GD P Sbjct: 582 GPEGKLGPLGA------PGEDGRPGPPGSI---GIRGQPGSMGLPGPKGSSGD------P 626 Query: 1011 GPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGET 1070 G P GE G+ G G++G G +G GP G G PG AG++GE Sbjct: 627 GKP--------------GEAGNAGVPGQRGAPGK-DGEV---GPSGPVGPPGLAGERGEQ 668 Query: 1071 VVGPQGPPGAPGLPGPPG----FGRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQP 1126 GP GP G GLPGPPG G+PGD G PG PG GP G PG G PG Sbjct: 669 --GPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGER-GNPGERGEPGIT 725 Query: 1127 GLPGSRNL 1134 GLPG + + Sbjct: 726 GLPGEKGM 733 Score = 335 bits (858), Expect = 2e-91 Identities = 284/816 (34%), Positives = 339/816 (41%), Gaps = 111/816 (13%) Query: 369 ISTAGEAEASSVPTGGPTLSMSTENPEEGVTPGPDNEERLAATAAGEAE-ALASMPGEVE 427 I T G A PTG P S + +PGP + + GE Sbjct: 422 IGTDGTPGAKG-PTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAG 480 Query: 428 ASGVAPGELDLSMSAQSLGEEATVGPSSEDSLTTAAAATEVSLSTFEDEEASGVP-TDGL 486 G PG + GEE GP + T V G P +DGL Sbjct: 481 PKG-EPGPHGIQGPIGPPGEEGKRGPRGDPG--TVGPPGPVGERGAPGNR--GFPGSDGL 535 Query: 487 APLTATMAPERAV-TSGP-GDEEDLAAATTEEPLITAGGEESGSPPPDGPPLPL-PTVAP 543 V +SGP G + D EP + +G+P GP L P AP Sbjct: 536 PGPKGAQGERGPVGSSGPKGSQGD--PGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAP 593 Query: 544 ERWITPAQREHVGMKGQAG------PKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGSGL 597 P +G++GQ G PKG GD PG P +G G A G Sbjct: 594 GEDGRPGPPGSIGIRGQPGSMGLPGPKGSSGD-----PGKPGEAGNAGVPGQRGAPGKDG 648 Query: 598 GWGSDVGSGSGDLVGSEQLLRGPPGP------PGPPGLPGIPGKPGTDVFMGPPGSPGED 651 G G L G E+ +GPPGP PGPPG PG GKPG G PG+ G Sbjct: 649 EVGPSGPVGPPGLAG-ERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPL 707 Query: 652 GPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQA 711 GP GE G PG G+PG+ TGLPG KG G GP+G +G PGP G G Sbjct: 708 GPRGERGNPGERGEPGI---TGLPGEKGMAGGHGPDGP---------KGSPGPSGTPGDT 755 Query: 712 GPPGVMGPPGPPGPPGPPGP-GCTMGLGFEDTEGS-GSTQLLNEPKLSRPTAAIGLKGEK 769 GPPG+ G PG G G PGP G G+G + EG+ G+ P P G GEK Sbjct: 756 GPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPTGEK 815 Query: 770 GDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDG 829 G+ GP+G +VGPPG RG PG + G + GP GPDG Sbjct: 816 GEPGPRG--------LVGPPGSRGNPG------------SRGENGPTGAVGFAGPQGPDG 855 Query: 830 LPGLPGFPGPRGPKGDTGLPG---------------FPGLKGEQGEKGEPGAILTEDIPL 874 PG+ G PG G KGD G PG PGLKG +G +G PGA Sbjct: 856 QPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGAT-----GF 910 Query: 875 ERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIM-QGP 933 G+ G PG GAPGP GP G PG +G GL G PG G G +G G PG +G Sbjct: 911 PGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGD 970 Query: 934 PGLPGPPGPPGPPG--AVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGS 991 PG G PGP GPPG +G + R MP G+P + G G+KG Sbjct: 971 PGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGKVGPTGATGDKGP 1030 Query: 992 WGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLM 1051 G G G G G GP GP + G G G GE+G++GD G + Sbjct: 1031 PGPVGPPGSNGPVGEPGPEGPAGN-----------DGTPGRDGAVGERGDRGD-PGPAGL 1078 Query: 1052 SGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPG-FGRPGDPGPPGPPGPPGPPAIL 1110 G G PG PGP G G+ G +G PG+ G GPPG G+ G PGP GP G G Sbjct: 1079 PGSQGAPGTPGPVGAPGDA--GQRGDPGSRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDR 1136 Query: 1111 G--------AAVALPGPPGPPGQPGLPGSRNLVTAF 1138 G L G PGPPG G GS + F Sbjct: 1137 GDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPF 1172 Score = 306 bits (785), Expect = 7e-83 Identities = 231/643 (35%), Positives = 274/643 (42%), Gaps = 115/643 (17%) Query: 577 PPEPSGPVGPTAGAEAEG--SGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPG 634 P P G P G + G G G LV +RG PGP GPPG G G Sbjct: 85 PVTPPGECCPVCSQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRG 144 Query: 635 KPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATG--------------------- 673 + GP G PG GP G G PG GQPG G G Sbjct: 145 E------RGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGL 198 Query: 674 ------------LPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPG 721 +PG G G RGP G G++G G G PG PG G GP G GP G Sbjct: 199 DEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEG 258 Query: 722 PPGPPGPPGPGCTMG----LGFEDTEGS-GSTQLLNEPKLSRPTAAIGLKGEKGDRGPKG 776 PPG PG G G +GF + G+ G P L GL+G KG+ G G Sbjct: 259 PPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPG 318 Query: 777 ERGMDGAS----IVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPG 832 +G G + +GP GPRG PG L G +P GP GP G+PG Sbjct: 319 SKGEAGPTGPMGAMGPLGPRGMPGERGRLGP---QGAPGQRGAHGMPGKPGPMGPLGIPG 375 Query: 833 LPGFPGPRGPKGDTGLPGFPGLKGEQGEKGE------------PGAILTEDIPLERLMGK 880 GFPG G KG+ G G G +G QG++GE PGAI T+ P + G Sbjct: 376 SSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPGAK--GP 433 Query: 881 KGEPGMHGAPGPMGPKGPPGHKGEF------GLPGRPGRPGLNGLKGTKGDPGVI----M 930 G PG G PG GP G PG +G G PG PG PG G G KG+PG Sbjct: 434 TGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGP 493 Query: 931 QGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKG 990 GPPG G GP G PG V G P+ R P + PGS L G +GE+G Sbjct: 494 IGPPGEEGKRGPRGDPGTV----GPPGPVGER---GAPGNRGFPGSDGLPGPKGAQGERG 546 Query: 991 SWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFL 1050 G G KG +GD G G PG P +G G+ G +G +G+ G + G+ Sbjct: 547 PVGSSGPKGSQGDPGRPGEPGLP-----------GARGLTGNPGVQGPEGKLGPL-GAPG 594 Query: 1051 MSGPPGLPGNPGPAGQKGET-VVGPQGPPGAPGLPGPPG-------FGRPGDPGPPGPPG 1102 G PG PG+ G GQ G + GP+G G PG PG G G PG G GP G Sbjct: 595 EDGRPGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSG 654 Query: 1103 PPGPPAILG-----------AAVALPGPPGPPGQPGLPGSRNL 1134 P GPP + G LPGPPGPPG+ G PG + + Sbjct: 655 PVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPGDQGV 697 Score = 278 bits (712), Expect = 2e-74 Identities = 230/665 (34%), Positives = 270/665 (40%), Gaps = 84/665 (12%) Query: 362 AGLAEVPISTAGEAEASSVPTGGPT--LSMSTENPEEGVTPGPDNEERLAATAAGEAEAL 419 AG A VP + V GP ++ E E+G PGP + L E Sbjct: 632 AGNAGVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQG-PPGPTGFQGLPGPPGPPGEG- 689 Query: 420 ASMPGEVEASGVAPGELDLSMSAQSLGEEATVGPSSEDSLTTAAAATEVSLSTFEDEEA- 478 PG+ GV PG+ GE G E +T ++ D Sbjct: 690 -GKPGD---QGV-PGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGPDGPKG 744 Query: 479 ----SGVPTDGLAPLTATMAPERAVTSGPGDEEDLAAATTEEPLITAGGEES-GSPPPDG 533 SG P D P M ER + PG + D + TAG + + G P P G Sbjct: 745 SPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLG 804 Query: 534 PPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTA--GAE 591 PP P + P R VG G G G +G+ G G +GP GP G + Sbjct: 805 PPGPAGPTGEKG--EPGPRGLVGPPGSRGNPGSRGENGPT--GAVGFAGPQGPDGQPGVK 860 Query: 592 AEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGED 651 E G D GS Q L G PGP GP G+PG+ G GT GPPG+ G Sbjct: 861 GEPGEPGQKGDAGSPG------PQGLAGSPGPHGPNGVPGLKGGRGTQ---GPPGATGFP 911 Query: 652 GPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQA 711 G AG GPPGP G PG G G PG +G G RG GS G GD G G PG PG KG Sbjct: 912 GSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDP 971 Query: 712 GPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGD 771 G G GP GPPGP G G +G+ + G + P + +G G GD Sbjct: 972 GEDGQPGPDGPPGPAGTTGQRGIVGMPGQ----RGERGMPGLPGPAGTPGKVGPTGATGD 1027 Query: 772 RGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLP 831 +GP G VGPPG GP G P GP G DG P Sbjct: 1028 KGPPGP--------VGPPGSNGPVGE---------------------PGPEGPAGNDGTP 1058 Query: 832 GLPGFPGPRGPKGD---TGLPGFPGLKGEQGEKGEPGAILTEDIPLER-LMGKKGEPGMH 887 G G G RG +GD GLPG G G G G PG P R +G G G Sbjct: 1059 GRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKR 1118 Query: 888 GAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVI-MQGPPGLPGPPGPPGPP 946 G PGP GP+G G G+ G G+ G G GL+G G PG QG G+PGP GP GPP Sbjct: 1119 GLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPP 1178 Query: 947 GAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGA 1006 G PV P K +PG I GV+G G G G GE G G Sbjct: 1179 G------------PVGPSGK----EGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGP 1222 Query: 1007 QGPPG 1011 GPPG Sbjct: 1223 PGPPG 1227 Score = 190 bits (483), Expect = 7e-48 Identities = 121/308 (39%), Positives = 141/308 (45%), Gaps = 53/308 (17%) Query: 502 GPGDEEDLAAATTEEPLITAGGEESGSPPPDGPPLPLPTVAPERWI-TPAQREHVGMKGQ 560 GPGD+ D E G P PDGPP P T + P QR GM G Sbjct: 964 GPGDKGDPG--------------EDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGL 1009 Query: 561 AGPKGEKGDAGEELP----GPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQL 616 GP G G G GPP P GP G G G+D G VG Sbjct: 1010 PGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGE--- 1066 Query: 617 LRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPG 676 RG G PGP GLPG G PGT GP G+PG+ G G+PG GP G PG G GLPG Sbjct: 1067 -RGDRGDPGPAGLPGSQGAPGTP---GPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPG 1122 Query: 677 MKGEKGARGPNGSVGEKGDPGNRG------LPGPPGKKGQAGPPGVMGPPGPPGPPGPPG 730 +G +G +G +G G++G G+RG LPGPPG G+ G G+ GP GP GPPGP G Sbjct: 1123 PQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVG 1182 Query: 731 PGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPG 790 P G P P G++G G+ GP+G G GPPG Sbjct: 1183 PSGKEG----------------NPGPLGPIGPPGVRGSVGEAGPEGPPGEP-----GPPG 1221 Query: 791 PRGPPGHI 798 P GPPGH+ Sbjct: 1222 PPGPPGHL 1229 Score = 68.2 bits (165), Expect = 5e-11 Identities = 46/110 (41%), Positives = 50/110 (45%), Gaps = 23/110 (20%) Query: 1030 NGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPGF 1089 N +G KG+KGE G L+ G+ G PGPAG P G G G GP G Sbjct: 106 NFGRGRKGQKGEPG------LVPVVTGIRGRPGPAG--------PPGSQGPRGERGPKG- 150 Query: 1090 GRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNLVTAFS 1139 RPG GP G G PG P PG PGPPG P PG L FS Sbjct: 151 -RPGPRGPQGIDGEPGVPG-------QPGAPGPPGHPSHPGPDGLSRPFS 192 >gi|148536825 alpha 1 type IV collagen preproprotein [Homo sapiens] Length = 1669 Score = 365 bits (937), Expect = e-100 Identities = 261/672 (38%), Positives = 299/672 (44%), Gaps = 143/672 (21%) Query: 526 SGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSGPVG 585 +G P P GPP P P ++ +G+ Q GPKG+KGD G SGP G Sbjct: 202 TGPPGPPGPPGP-----------PGEKGQMGLSFQ-GPKGDKGDQGV--------SGPPG 241 Query: 586 PTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGI-----PGKPGTDV 640 A+ + G D + +G G PG G+PG+ PGKPG Sbjct: 242 VPGQAQVQEKG------------DFATKGE--KGQKGEPGFQGMPGVGEKGEPGKPG--- 284 Query: 641 FMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNG------SVGEKG 694 P G PG+DG GE G PG G+PG G G G +GEKG GP G G G Sbjct: 285 ---PRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGPQGEKGEAGPPGPPGIVIGTGPLG 341 Query: 695 DPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEP 754 + G RG PG PG +G+ GP G G PG PGPPG P PG GF G + Sbjct: 342 EKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGT 401 Query: 755 KLSRPTAAIGLKGEKGDRGPKGERGMDGASI---VGPPGPRGPPGHIKVLSNSLINITHG 811 L P+ GL G G GP G+ G + GPPG +GPPG I G Sbjct: 402 SLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQPGPPGDQGPPG---------IPGQPG 452 Query: 812 FMN-------------FSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLP--------- 849 F+ DI GPPGP G PG GFPG G KGD GLP Sbjct: 453 FIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVP 512 Query: 850 ---GFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFG 906 G PGL G+ G KGEPG + RL G KG+PG G PG G G PG G G Sbjct: 513 GPQGTPGLIGQPGAKGEPGEFYFD----LRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPG 568 Query: 907 LPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCK 966 LPG G PG GLKG +G PG + G PG G GPPGPPG G PI + Sbjct: 569 LPGPKGSPGSVGLKGERGPPGGV--GFPGSRGDTGPPGPPG-----YGPAGPIGDKGQAG 621 Query: 967 MPVDTAHPGSP-------ELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYL 1019 P PG P +++ G G +G G PG G +GD+G G PG P Sbjct: 622 FPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDRGFPGTPGRP------ 675 Query: 1020 RHFLNNLKGENG-----DKGFKGEKGEKGDINGSFLMSGPP---------GLPGNPGPAG 1065 L GE G GF G G KG ++G GPP GLPGNPG G Sbjct: 676 -----GLPGEKGAVGQPGIGFPGPPGPKG-VDGLPGDMGPPGTPGRPGFNGLPGNPGVQG 729 Query: 1066 QKGETVVGPQGPPGAPGLPGPPG-------FGRPGDPGPPGPPGPPGPPAILGAAVALPG 1118 QKGE VG G G PGLPG PG G PG PG G GPPG I G PG Sbjct: 730 QKGEPGVGLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGE----PG 785 Query: 1119 PPGPPGQPGLPG 1130 PPG PG G PG Sbjct: 786 PPGLPGSVGSPG 797 Score = 360 bits (924), Expect = 5e-99 Identities = 267/662 (40%), Positives = 304/662 (45%), Gaps = 134/662 (20%) Query: 556 GMKGQAGPKGEKGDAGE-ELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSE 614 G+KGQ G +G G G PG P GP GP G +G L G++ Sbjct: 43 GVKGQKGERGLPGLQGVIGFPGMQGPEGPQGPP------------GQKGDTGEPGLPGTK 90 Query: 615 QLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGL 674 RGPPG G PG PG+PG PG D GPPG PG +G GE GP GP G PG G G Sbjct: 91 GT-RGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFAGNPGP 149 Query: 675 PGMKGEKGARGPN-GSV------GEKGDPGNRGLPGPPGK---KGQAGPPGVMGPPGPPG 724 PG+ G KG G G V GE+G PG G PGPPG +G GPPG GPPGPPG Sbjct: 150 PGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGLPGLQGPVGPPGFTGPPGPPG 209 Query: 725 PPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGE---KGDRGPKGERGMD 781 PPGPPG MGL F+ +G Q ++ P A + KG+ KG++G KGE G Sbjct: 210 PPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPGVPGQAQVQEKGDFATKGEKGQKGEPGFQ 269 Query: 782 GASIVGP------PGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPG 835 G VG PGPRG PG G P G PG G PGL G Sbjct: 270 GMPGVGEKGEPGKPGPRGKPGK------------DGDKGEKGSP---GFPGEPGYPGLIG 314 Query: 836 FPGPRGPKGDTGLPGFPGLK------GEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGA 889 GP+G KG+ G PG PG+ GE+GE+G PG G +GEPG G Sbjct: 315 RQGPQGEKGEAGPPGPPGIVIGTGPLGEKGERGYPGT-----------PGPRGEPGPKGF 363 Query: 890 PGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPG---LPGPPGPPGPP 946 PG G GPPG G G PG PG G KG +G PG + GP G LPGPPG PGPP Sbjct: 364 PGLPGQPGPPGLPVP-GQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPP 422 Query: 947 GAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSW-------------- 992 G G + P P + P PG P I G KG+KG Sbjct: 423 GQPGYTNGIVECQPGPPGDQGPPGI--PGQPGFIGEIGEKGQKGESCLICDIDGYRGPPG 480 Query: 993 --------GLPGSKGEKGDQG------AQGPPGPPLDLAYLR-----------HFLNNLK 1027 G PG G KGD+G G PGP + +F LK Sbjct: 481 PQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLK 540 Query: 1028 GENGDKGFKGEKGEKGDINGSFLMSGPPGLPG---NPGPAGQKGETVVGPQGPPGAPGL- 1083 G+ GD GF G+ G G GS G PGLPG +PG G KGE GP G G PG Sbjct: 541 GDKGDPGFPGQPGMTGRA-GSPGRDGHPGLPGPKGSPGSVGLKGER--GPPGGVGFPGSR 597 Query: 1084 -----PGPPGFG---------RPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLP 1129 PGPPG+G + G PG PG PG PGP G V LPGPPG GLP Sbjct: 598 GDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGA---EGLP 654 Query: 1130 GS 1131 GS Sbjct: 655 GS 656 Score = 358 bits (920), Expect = 2e-98 Identities = 260/679 (38%), Positives = 307/679 (45%), Gaps = 152/679 (22%) Query: 556 GMKGQAGPKGEKGDAGEE---------LPGPPEPSGPVGPTA--GAEAEGSGLGW-GSDV 603 G++G+ GP G G G GPP GP G + G + E G+ G D+ Sbjct: 779 GIRGEPGPPGLPGSVGSPGVPGIGPPGARGPPGGQGPPGLSGPPGIKGEKGFPGFPGLDM 838 Query: 604 GSGSGDL-------VGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGE 656 GD + + L G PG G PG+PG PG G MG PG PG GP G Sbjct: 839 PGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGA 898 Query: 657 PGPPGPEGQ---PGVDGATGLPGMKGEKG---------------------------ARGP 686 PG PG +G PG G G PG+KG+KG +G Sbjct: 899 PGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQ 958 Query: 687 NGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPG------PPGPPGP-GCTMGLGF 739 G +GEKG G+ G PG PGK GQAG PG GP G PG PG PGP G G+G Sbjct: 959 IGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVGGMGL 1018 Query: 740 EDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIK 799 T G P + P + GL G+KG +G KG+ G G +G PG RG G Sbjct: 1019 PGTPGEKGV-----PGIPGPQGSPGLPGDKGAKGEKGQAGPPG---IGIPGLRGEKGD-- 1068 Query: 800 VLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQG 859 G F P G G G+PG+PG PG +G G G PG PGL GE+G Sbjct: 1069 ----------QGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKG 1118 Query: 860 EKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGP---KGPPG---------HKGEFGL 907 +KG PG L+ + G KGE G+ G PGP GP KG PG KGE GL Sbjct: 1119 DKGLPG--------LDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGL 1170 Query: 908 PGR--PGRPGLNGLKGTKGDPGVI-MQGPPGLPG---------PPGPPGPPGAVINIKGA 955 PGR PG PG G KG+KG+ G + G PG+PG PPGP G PG + G+ Sbjct: 1171 PGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPG----LPGS 1226 Query: 956 IFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLD 1015 P D G P L G+ G G GLPG G KGD+G G PG P Sbjct: 1227 PGHATEGPKG----DRGPQGQPGL---PGLPGPMGPPGLPGIDGVKGDKGNPGWPGAP-- 1277 Query: 1016 LAYLRHFLNNLKGENGDKGFKGEKGEKGD--INGSFLMSGPPGLPGNPGPAGQKGETVV- 1072 + G GD GF+G G G I GS GPPG+PG GP G G + Sbjct: 1278 ---------GVPGPKGDPGFQGMPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIK 1328 Query: 1073 ---GPQGPPGAPGLPGPPGFGRP-----GDPGPPGPPGPPGPPAILG-----------AA 1113 G QG PGA GLPGPPG P G+PG PGP GPPG + G Sbjct: 1329 GDQGDQGVPGAKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGL 1388 Query: 1114 VALPGPPGPPGQPGLPGSR 1132 V +PGPPG PG G PG + Sbjct: 1389 VGIPGPPGIPGFDGAPGQK 1407 Score = 358 bits (919), Expect = 2e-98 Identities = 281/704 (39%), Positives = 333/704 (47%), Gaps = 133/704 (18%) Query: 526 SGSPPPDGPP-LPLPTVAPERWITPAQREHVGMKGQAGPKG------EKGDAGEELPGPP 578 +GSP DG P LP P +P VG+KG+ GP G +GD G PGPP Sbjct: 558 AGSPGRDGHPGLPGPKGSPGS---------VGLKGERGPPGGVGFPGSRGDTGP--PGPP 606 Query: 579 E--PSGPVGPTAGAEAEGSGLGWGSDVGSGS-GDLV------GSEQLLRGP--PGPPGPP 627 P+GP+G A G G G G +V G+E L P PGP G Sbjct: 607 GYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPGFPGPQGDR 666 Query: 628 GLPGIPGKPGTDV-----------FMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPG 676 G PG PG+PG F GPPG G DG G+ GPPG G+PG +G G PG Sbjct: 667 GFPGTPGRPGLPGEKGAVGQPGIGFPGPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPG 726 Query: 677 MKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGV------MGPPG------PPG 724 ++G+KG G G G KG PG G+PG PG+KG G PGV +GPPG PG Sbjct: 727 VQGQKGEPGV-GLPGLKGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPG 785 Query: 725 PPGPPG----PGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRG------- 773 PPG PG PG G+G G Q P LS P G+KGEKG G Sbjct: 786 PPGLPGSVGSPGVP-GIGPPGARGPPGGQ--GPPGLSGPP---GIKGEKGFPGFPGLDMP 839 Query: 774 -PKGERGMDG-------ASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPP 825 PKG++G G + + G PG +G PG I S G M P G P Sbjct: 840 GPKGDKGAQGLPGITGQSGLPGLPGQQGAPG-IPGFPGS-----KGEMGVMGTPGQPGSP 893 Query: 826 GPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTED-IPLERLMGKKGEP 884 GP G PGLPG G G G +G G PGLKG++G+ G PG + D + + + G+KG+ Sbjct: 894 GPVGAPGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKPGSMDKVDMGSMKGQKGDQ 953 Query: 885 GMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPG 944 G G GP+G KG G G G+PG+ G+ G G G KGDPG+ G PG PG PGP G Sbjct: 954 GEKGQIGPIGEKGSRGDPGTPGVPGKDGQAGQPGQPGPKGDPGI--SGTPGAPGLPGPKG 1011 Query: 945 PPGAVINIKGAIFPIPVRPHCK-MPVDTAHPGSPELITFHGVKGEKGSWG-----LPGSK 998 G + +P P K +P GSP L G KGEKG G +PG + Sbjct: 1012 SVGGM--------GLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGPPGIGIPGLR 1063 Query: 999 GEKGDQGAQGPPGPPLDLAYLRHF-------LNNLKGENGDKGFKG------EKGEKG-- 1043 GEKGDQG G PG P + LKG G G+ G EKG+KG Sbjct: 1064 GEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLPGEKGDKGLP 1123 Query: 1044 ---DINGSFLMSGPPGLPGNPGPAGQKGET----VVGPQGPPGAPGLPGP--PGF----- 1089 I G +G PG PG GPAGQKGE + G G G PGLPG PGF Sbjct: 1124 GLDGIPGVKGEAGLPGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKG 1183 Query: 1090 --GRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGS 1131 G G+ G PG G PG P G GPPGP GQPGLPGS Sbjct: 1184 DKGSKGEVGFPGLAGSPGIPGSKGEQ-GFMGPPGPQGQPGLPGS 1226 Score = 355 bits (911), Expect = 2e-97 Identities = 260/665 (39%), Positives = 311/665 (46%), Gaps = 97/665 (14%) Query: 527 GSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEE-----------LP 575 GSP P G P + + P + G+ GQ G GE G+ G++ Sbjct: 417 GSPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYR 476 Query: 576 GPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGL---PGI 632 GPP P GP G +G+ G+ + + G PGP G PGL PG Sbjct: 477 GPPGPQGPPGE----------IGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGA 526 Query: 633 PGKPGTDVF-------MGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARG 685 G+PG F G PG PG+ G G G PG +G PG+ G G PG G KG RG Sbjct: 527 KGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERG 586 Query: 686 PNGSVGEKGDPGNRGLPGPPG--------KKGQAGPPGVMGPPGPPGP----------PG 727 P G VG G G+ G PGPPG KGQAG PG G PG PGP PG Sbjct: 587 PPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPG 646 Query: 728 PPGP-GCTMGLGFEDTEGS-GSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGA-S 784 PPG G GF +G G P L A+G G G GP G +G+DG Sbjct: 647 PPGAEGLPGSPGFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGI-GFPGPPGPKGVDGLPG 705 Query: 785 IVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKG 844 +GPPG G PG + N + G VG PG GLPGLPG PG G KG Sbjct: 706 DMGPPGTPGRPGFNGLPGNPGVQGQKGEPG-------VGLPGLKGLPGLPGIPGTPGEKG 758 Query: 845 DTGLPGFPG------------LKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGP 892 G+PG PG ++GE G G PG++ + +P +G G G G GP Sbjct: 759 SIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPG---IGPPGARGPPGGQGP 815 Query: 893 MGPKGPPGHKGEFGLPGRPG--RPGLNGLKGTKGDPGVIMQ-GPPGLPGPPGPPGPPGAV 949 G GPPG KGE G PG PG PG G KG +G PG+ Q G PGLPG G PG PG Sbjct: 816 PGLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLPGLPGQQGAPGIPGFP 875 Query: 950 INIKG--AIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQ 1007 KG + P +P PV PG P HG G G G PG KG+KGD G Sbjct: 876 -GSKGEMGVMGTPGQPGSPGPVGA--PGLPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLP 932 Query: 1008 GPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQK 1067 G PG +D + + ++KG+ GD+G KG+ G G+ GS G PG+PG G AGQ Sbjct: 933 GKPGS-MD----KVDMGSMKGQKGDQGEKGQIGPIGE-KGSRGDPGTPGVPGKDGQAGQP 986 Query: 1068 GETVVGPQGPPGAPGLPGPPGFGRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPG 1127 G+ GP+G PG G PG PG PG G G G PG P G +PG PGP G PG Sbjct: 987 GQP--GPKGDPGISGTPGAPGL--PGPKGSVGGMGLPGTPGEKG----VPGIPGPQGSPG 1038 Query: 1128 LPGSR 1132 LPG + Sbjct: 1039 LPGDK 1043 Score = 349 bits (896), Expect = 9e-96 Identities = 273/718 (38%), Positives = 314/718 (43%), Gaps = 149/718 (20%) Query: 527 GSPPPDGPPLP-----LP-TVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGP--- 577 G+P P G P P LP P P Q G G+ G KG++G G LPGP Sbjct: 350 GTPGPRGEPGPKGFPGLPGQPGPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGR 409 Query: 578 ---PEPSGPVGPTAGAEAEGSGL--------------------GWGSDVGS----GSGDL 610 P P G GP G +G+ G+ ++G G L Sbjct: 410 DGLPGPPGSPGPP-GQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCL 468 Query: 611 VGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGP---PGPEGQPG 667 + RGPPGP GPPG G PG+PG G G PG DG AG PGP PG GQPG Sbjct: 469 ICDIDGYRGPPGPQGPPGEIGFPGQPGAK---GDRGLPGRDGVAGVPGPQGTPGLIGQPG 525 Query: 668 VDGATG-------LPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPP 720 G G L G KG+ G G G G G PG G PG PG KG G G+ G Sbjct: 526 AKGEPGEFYFDLRLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGER 585 Query: 721 GPPG------------PPGPPGPGCTMGLGFEDTEG----SGSTQL---LNEP----KLS 757 GPPG PPGPPG G +G + G GS L EP L Sbjct: 586 GPPGGVGFPGSRGDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLP 645 Query: 758 RPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSD 817 P A GL G G GP+G+RG G PG G PG + I Sbjct: 646 GPPGAEGLPGSPGFPGPQGDRGFPGT-----PGRPGLPGEKGAVGQPGIGFP-------- 692 Query: 818 IPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERL 877 GPPGP G+ GLPG GP G G G G PG G QG+KGEPG + L L Sbjct: 693 -----GPPGPKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPG------VGLPGL 741 Query: 878 MGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRP------GRPGLNGLKGTKGDPGVIMQ 931 G G PG+ G PG G G PG GE G G P G PG GL G+ G PGV Sbjct: 742 KGLPGLPGIPGTPGEKGSIGVPGVPGEHGAIGPPGLQGIRGEPGPPGLPGSVGSPGVPGI 801 Query: 932 GPPGLPGPPGPPGPPG--AVINIKGAIFPIPVRPHCKMPVDTAHPGSPEL--IT----FH 983 GPPG GPPG GPPG IKG P P MP G+ L IT Sbjct: 802 GPPGARGPPGGQGPPGLSGPPGIKGE-KGFPGFPGLDMPGPKGDKGAQGLPGITGQSGLP 860 Query: 984 GVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKG 1043 G+ G++G+ G+PG G KG+ G G PG P + L GE GD GF G G +G Sbjct: 861 GLPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVG--APGLPGEKGDHGFPGSSGPRG 918 Query: 1044 D--INGSFLMSGPPGLPGNPGP---------AGQKGET----VVGP------QGPPGAPG 1082 D + G G GLPG PG GQKG+ +GP +G PG PG Sbjct: 919 DPGLKGD---KGDVGLPGKPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPG 975 Query: 1083 LPGPPG-FGRPGDPGP---------PGPPGPPGPPAILGAAVALPGPPGPPGQPGLPG 1130 +PG G G+PG PGP PG PG PGP +G + LPG PG G PG+PG Sbjct: 976 VPGKDGQAGQPGQPGPKGDPGISGTPGAPGLPGPKGSVG-GMGLPGTPGEKGVPGIPG 1032 Score = 343 bits (881), Expect = 5e-94 Identities = 260/680 (38%), Positives = 304/680 (44%), Gaps = 153/680 (22%) Query: 549 PAQREHVGMKGQAGPKGEKGDAGEELPGPPE---PSGPVGPTAGAEAEGSGLGWGSDVGS 605 P + + G+ G+ GP+GEKG+AG PGPP +GP+G G+ G Sbjct: 304 PGEPGYPGLIGRQGPQGEKGEAGP--PGPPGIVIGTGPLGEKGERGYPGTPGPRGEPGPK 361 Query: 606 GSGDLVGSEQLLRGPPGPP-----GPPGLPG--------------IPGKPGTDVFMGPPG 646 G L G GPPG P G PG PG +PG G D GPPG Sbjct: 362 GFPGLPGQP----GPPGLPVPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPG 417 Query: 647 SPGEDGPAG--------EPGPPGPEGQPGVDGATGLPGMKGEKGARGPN----------G 688 SPG G G +PGPPG +G PG+ G G G GEKG +G + G Sbjct: 418 SPGPPGQPGYTNGIVECQPGPPGDQGPPGIPGQPGFIGEIGEKGQKGESCLICDIDGYRG 477 Query: 689 SVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPG----PGCT-------MGL 737 G +G PG G PG PG KG G PG G G PGP G PG PG L Sbjct: 478 PPGPQGPPGEIGFPGQPGAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDL 537 Query: 738 GFEDTEG-------------SGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGA- 783 + +G +GS P L P + G G KG+RGP G G G+ Sbjct: 538 RLKGDKGDPGFPGQPGMTGRAGSPGRDGHPGLPGPKGSPGSVGLKGERGPPGGVGFPGSR 597 Query: 784 SIVGPPGP--RGPPGHIKVLSNSLINITHGFMNF-------SDIPELVGPPGPDGLPGLP 834 GPPGP GP G I + G I L GPPG +GLPG P Sbjct: 598 GDTGPPGPPGYGPAGPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSP 657 Query: 835 GFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMG 894 GFPGP+G +G G PG PGL GE+G G+PG G PGP G Sbjct: 658 GFPGPQGDRGFPGTPGRPGLPGEKGAVGQPGI---------------------GFPGPPG 696 Query: 895 PKGPPGHKGEFGLPGRPGRPGLNGL------KGTKGDPGVIMQGPPGLPGPPGPPGPPGA 948 PKG G G+ G PG PGRPG NGL +G KG+PGV + G GLPG PG PG PG Sbjct: 697 PKGVDGLPGDMGPPGTPGRPGFNGLPGNPGVQGQKGEPGVGLPGLKGLPGLPGIPGTPGE 756 Query: 949 VINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEK-----GD 1003 KG+I +P +P + G P L G++GE G GLPGS G G Sbjct: 757 ----KGSI-GVP-----GVPGEHGAIGPPGL---QGIRGEPGPPGLPGSVGSPGVPGIGP 803 Query: 1004 QGAQGPP---GPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKG----DINGSFLMSGPPG 1056 GA+GPP GPP G +G G KGEKG G D+ G G G Sbjct: 804 PGARGPPGGQGPP--------------GLSGPPGIKGEKGFPGFPGLDMPGPKGDKGAQG 849 Query: 1057 LPGNPGPAGQKGETVVGPQGPPGAPGLPGPPG----FGRPGDPGPPGPPGPPGPPAILGA 1112 LPG G +G G + G QG PG PG PG G G PG PG PGP G PG P G Sbjct: 850 LPGITGQSGLPG--LPGQQGAPGIPGFPGSKGEMGVMGTPGQPGSPGPVGAPGLPGEKGD 907 Query: 1113 AVALPGPPGPPGQPGLPGSR 1132 PG GP G PGL G + Sbjct: 908 H-GFPGSSGPRGDPGLKGDK 926 Score = 313 bits (802), Expect = 7e-85 Identities = 247/647 (38%), Positives = 282/647 (43%), Gaps = 133/647 (20%) Query: 600 GSDVGSGSG--DLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEP 657 G GSG G D G ++G G G PGL G+ G PG GP G PG+ G GEP Sbjct: 29 GGCAGSGCGKCDCHG----VKGQKGERGLPGLQGVIGFPGMQGPEGPQGPPGQKGDTGEP 84 Query: 658 GPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVM 717 G PG +G G GA+G PG G G G +G G G PG G G G G G PG Sbjct: 85 GLPGTKGTRGPPGASGYPGNPGLPGIPGQDGPPGPPGIPGCNGTKGERGPLGPPGLPGFA 144 Query: 718 GPPGPPGPPGPPG-PGCTMG----------LGFEDTEGSGSTQLLNEPKLSRPTAAIGL- 765 G PGPPG PG G PG +G GF G+ L P L P G Sbjct: 145 GNPGPPGLPGMKGDPGEILGHVPGMLLKGERGFPGIPGTPGPPGL--PGLQGPVGPPGFT 202 Query: 766 --KGEKGDRGPKGERGMDGASIVGPPGPR------GPPGHIKVLSNSLINITHGFMNFSD 817 G G GP GE+G G S GP G + GPPG V + + F + Sbjct: 203 GPPGPPGPPGPPGEKGQMGLSFQGPKGDKGDQGVSGPPG---VPGQAQVQEKGDFATKGE 259 Query: 818 IPELVGPPGPDGLPGL-----PGFPGPR------GPKGDTGLPGFP---------GLKGE 857 + G PG G+PG+ PG PGPR G KG+ G PGFP G +G Sbjct: 260 KGQ-KGEPGFQGMPGVGEKGEPGKPGPRGKPGKDGDKGEKGSPGFPGEPGYPGLIGRQGP 318 Query: 858 QGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGL- 916 QGEKGE G I + G GE G G PG GP+G PG KG GLPG+PG PGL Sbjct: 319 QGEKGEAGPPGPPGIVIG--TGPLGEKGERGYPGTPGPRGEPGPKGFPGLPGQPGPPGLP 376 Query: 917 -------------NGLKGTKGDPGVIMQGP---PGLPGPPGPPGPPGAVINIKGAIFPIP 960 G KG +G PG + GP GLPGPPG PGPPG G + P Sbjct: 377 VPGQAGAPGFPGERGEKGDRGFPGTSLPGPSGRDGLPGPPGSPGPPGQPGYTNGIVECQP 436 Query: 961 VRPHCKMPVDTAHPGSPELITFHGVKGEK----------------------GSWGLPGSK 998 P + P PG P I G KG+K G G PG Sbjct: 437 GPPGDQGP--PGIPGQPGFIGEIGEKGQKGESCLICDIDGYRGPPGPQGPPGEIGFPGQP 494 Query: 999 GEKGDQ------GAQGPPGPPLDLAYLR-----------HFLNNLKGENGDKGFKGEKGE 1041 G KGD+ G G PGP + +F LKG+ GD GF G+ G Sbjct: 495 GAKGDRGLPGRDGVAGVPGPQGTPGLIGQPGAKGEPGEFYFDLRLKGDKGDPGFPGQPGM 554 Query: 1042 KGDINGSFLMSGPPGLP---GNPGPAGQKGETVVGPQGPPGAPGL------PGPPGF--- 1089 G GS G PGLP G+PG G KGE GP G G PG PGPPG+ Sbjct: 555 TGRA-GSPGRDGHPGLPGPKGSPGSVGLKGER--GPPGGVGFPGSRGDTGPPGPPGYGPA 611 Query: 1090 ------GRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPG 1130 G+ G PG PG PG PGP G V LPGPPG G PG PG Sbjct: 612 GPIGDKGQAGFPGGPGSPGLPGPKGEPGKIVPLPGPPGAEGLPGSPG 658 Score = 271 bits (693), Expect = 3e-72 Identities = 210/585 (35%), Positives = 252/585 (43%), Gaps = 117/585 (20%) Query: 523 GEESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGE---KGDAGEE-LPGPP 578 GE P P P P AP P ++ G G +GP+G+ KGD G+ LPG P Sbjct: 879 GEMGVMGTPGQPGSPGPVGAPG---LPGEKGDHGFPGSSGPRGDPGLKGDKGDVGLPGKP 935 Query: 579 EPS-----GPVGPTAGAEAEGSGLGWGSDVGS----GSGDLVGSEQLLRGPPGPPGPPGL 629 G + G + E +G + GS G+ + G + G PG PGP G Sbjct: 936 GSMDKVDMGSMKGQKGDQGEKGQIGPIGEKGSRGDPGTPGVPGKDGQA-GQPGQPGPKGD 994 Query: 630 PGIPGKPGTDVFMGPPGS------PGEDGPAGEPGPPGPEGQPGVDG------------- 670 PGI G PG GP GS PG G G PG PGP+G PG+ G Sbjct: 995 PGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVPGIPGPQGSPGLPGDKGAKGEKGQAGP 1054 Query: 671 -ATGLPGMKGEKGARGPNG---SVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPP 726 G+PG++GEKG +G G S GEKG+ G+ G+PG PG G G PG +G PG PG P Sbjct: 1055 PGIGIPGLRGEKGDQGIAGFPGSPGEKGEKGSIGIPGMPGSPGLKGSPGSVGYPGSPGLP 1114 Query: 727 GPPGPGCTMGL-GFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGD------RGPKGERG 779 G G GL G +G P PT G KGE G G KGE G Sbjct: 1115 GEKGDKGLPGLDGIPGVKGEAGL-----PGTPGPTGPAGQKGEPGSDGIPGSAGEKGEPG 1169 Query: 780 MDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPG- 838 + G G PG +G G + + + G +GPPGP G PGLPG PG Sbjct: 1170 LPGRGFPGFPGAKGDKGSKGEVGFPGLAGSPGIPGSKGEQGFMGPPGPQGQPGLPGSPGH 1229 Query: 839 ----PRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMG 894 P+G +G G PG PGL G G G PG ++ + G KG PG GAPG G Sbjct: 1230 ATEGPKGDRGPQGQPGLPGLPGPMGPPGLPG--------IDGVKGDKGNPGWPGAPGVPG 1281 Query: 895 PKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVI-MQGPPGLPGP-------------- 939 PKG PG +G +PG G PG+ G KG G PGV QGP GLPG Sbjct: 1282 PKGDPGFQG---MPGIGGSPGITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPG 1338 Query: 940 ----PGPPGPPGAVINIKGAI-FPIPVRPHCKMPVD--------------TAHPGSPELI 980 PGPPGPPG IKG P P P + PG P + Sbjct: 1339 AKGLPGPPGPPGPYDIIKGEPGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIP 1398 Query: 981 TFHGVKGEKGSWGL------------PGSKGEKGDQGAQGPPGPP 1013 F G G+KG G PG G G+ GPPG P Sbjct: 1399 GFDGAPGQKGEMGPAGPTGPRGFPGPPGPDGL---PGSMGPPGTP 1440 Score = 228 bits (581), Expect = 3e-59 Identities = 202/564 (35%), Positives = 232/564 (41%), Gaps = 107/564 (18%) Query: 424 GEVEASGVAPGELDL----SMSAQS--LGEEATVGPSSEDSLTTAAAATEVSLSTFEDEE 477 G+V G PG +D SM Q GE+ +GP E + D Sbjct: 927 GDVGLPG-KPGSMDKVDMGSMKGQKGDQGEKGQIGPIGEKG-------------SRGDPG 972 Query: 478 ASGVP-TDGLAPLTATMAPERAVTSGPGDEEDLAAATTEEPLITAGGEE-SGSPPPDGPP 535 GVP DG A P+ PG A P + GG G+P G P Sbjct: 973 TPGVPGKDGQAGQPGQPGPK----GDPGISGTPGAPGLPGPKGSVGGMGLPGTPGEKGVP 1028 Query: 536 -LPLPTVAPERWITPAQREHVGMKGQAGP--------KGEKGDAG-EELPGPPEPSGPVG 585 +P P +P P + G KGQAGP +GEKGD G PG P G G Sbjct: 1029 GIPGPQGSPG---LPGDKGAKGEKGQAGPPGIGIPGLRGEKGDQGIAGFPGSPGEKGEKG 1085 Query: 586 PTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPP 645 GS G GS GS G PG G GLPG+ G PG G P Sbjct: 1086 SIGIPGMPGSP---GLKGSPGSVGYPGSP----GLPGEKGDKGLPGLDGIPGVKGEAGLP 1138 Query: 646 GSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGE-----KGARGPNGSVGEKGDPGNRG 700 G+PG GPAG+ G PG +G PG G G PG+ G GA+G GS GE G PG G Sbjct: 1139 GTPGPTGPAGQKGEPGSDGIPGSAGEKGEPGLPGRGFPGFPGAKGDKGSKGEVGFPGLAG 1198 Query: 701 LPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQ-LLNEPKLSRP 759 PG PG KG+ G MGPPGP G PG PG + G E +G Q P L P Sbjct: 1199 SPGIPGSKGEQG---FMGPPGPQGQPGLPG---SPGHATEGPKGDRGPQGQPGLPGLPGP 1252 Query: 760 TAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIP 819 GL G G +G KG G GA G PGP+G PG G P Sbjct: 1253 MGPPGLPGIDGVKGDKGNPGWPGAP--GVPGPKGDPGF------------QGMPGIGGSP 1298 Query: 820 ELVGPPGPDGLPGLPGFPGPRG---------PKGDTGLPGFPGLKGEQGE-------KGE 863 + G G G PG+PGF GP+G +GD G+PG GL G G KGE Sbjct: 1299 GITGSKGDMGPPGVPGFQGPKGLPGLQGIKGDQGDQGVPGAKGLPGPPGPPGPYDIIKGE 1358 Query: 864 PGAILTEDIP----LERLMGKKGE---------------PGMHGAPGPMGPKGPPGHKGE 904 PG E P L+ L G KG+ PG GAPG G GP G G Sbjct: 1359 PGLPGPEGPPGLKGLQGLPGPKGQQGVTGLVGIPGPPGIPGFDGAPGQKGEMGPAGPTGP 1418 Query: 905 FGLPGRPGRPGLNGLKGTKGDPGV 928 G PG PG GL G G G P V Sbjct: 1419 RGFPGPPGPDGLPGSMGPPGTPSV 1442 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 363 bits (933), Expect = e-100 Identities = 278/721 (38%), Positives = 322/721 (44%), Gaps = 115/721 (15%) Query: 495 PERAVTSGPGDEEDLAAATTEEPLITAGGEESGSPP----PDGPPLPLPTVAPERWITPA 550 P R GP A A E A G GSP P P P +P P Sbjct: 1277 PGRTGAPGPQGPPGSATAKGERGFPGADGRP-GSPGRAGNPGTPGAPGLKGSPG---LPG 1332 Query: 551 QREHVGMKGQAGPKGEKGDAGEEL-------------PGPPEPSGPVGPTAGAEAEGSGL 597 R G +G GPKGE G G+ + PGP P GP GP G Sbjct: 1333 PRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPG 1392 Query: 598 GWGSDVGSGSGDLVGSEQLLRGPPGP------PGPPGLPGIPGKPGTDVFMGPPGSPGED 651 G+ + GD + RGPPGP PG PGLPG+PG PG +GPPG GE Sbjct: 1393 LPGTAMKGDKGD-----RGERGPPGPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEK 1447 Query: 652 GPA--GEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKG 709 G + G PG PG G PG G G PG G KG RG G +GE G+ G RG PGP G +G Sbjct: 1448 GDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRG 1507 Query: 710 QAGPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEK 769 PGV G PG GP GPPGP G G +P + P A G KGEK Sbjct: 1508 L---PGVAGRPGAKGPEGPPGPTGRQG-------EKGEPGRPGDPAVVGPAVA-GPKGEK 1556 Query: 770 GDRGP---------KGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPE 820 GD GP +GERG G + G PGP+G PG + G + P Sbjct: 1557 GDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPI---------GLTGRAGPPG 1607 Query: 821 LVGPPGPDGLPGLPGFPGPRGP---------KGDTGLPGFPGLKGEQGEKGEPGAI-LTE 870 GPPG G PG PG PGP GP KGD G PG PGL G+ GE+G GA + Sbjct: 1608 DSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRG 1667 Query: 871 DIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGR-------------PGRPGLN 917 + + G GE G +G+PG GPKG G G G PGR PG G Sbjct: 1668 PVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQE 1727 Query: 918 GLKGTKGDPGVI----MQGPPGLPGPPGPPGPPG--AVINIKGAIFP--IPVRPHCKMPV 969 G +G KGDPG+ +G G GPPGP G PG KG P + R Sbjct: 1728 GPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKP 1787 Query: 970 DTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPG-PPLDLAYLRHFLNNLKG 1028 A P P G G+ G GLPG +GE+G G GPPG P + LN G Sbjct: 1788 GAAGPSGPNGAA--GKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNG 1845 Query: 1029 ENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGET-VVGPQGPPGAPGLPGPP 1087 E GD G G KGEKGD SG G G GP G++G ++GPQGPPG PG GPP Sbjct: 1846 EPGDPGEDGRKGEKGD-------SGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPP 1898 Query: 1088 GFGRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNLVTAFSNMDDMLQK 1147 G G PG PG GP G G G LPG G G+PG + N+D +L+ Sbjct: 1899 GQGFPGVPGGTGPKGDRGETGSKGEQ-GLPGERGLRGEPG---------SVPNVDRLLET 1948 Query: 1148 A 1148 A Sbjct: 1949 A 1949 Score = 363 bits (931), Expect = e-100 Identities = 318/971 (32%), Positives = 392/971 (40%), Gaps = 205/971 (21%) Query: 280 PPTPSSPFEDMELSGEPVPEGT-LETTNMSIIQHSSPKQGSGEILNDTLEGVHSVDGDPI 338 PP P P D G P GT ++ + P G G I G+ + G P Sbjct: 1375 PPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAPGE-PGLPGLPGSPG 1433 Query: 339 TDSGSGAGAFLDIAEEKNLAATAAGLAEVPISTAGEAEASSVPTGGPT--------LSMS 390 G E+ + A GL P S + GP L + Sbjct: 1434 PQGPVGPPG--KKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEA 1491 Query: 391 TENPEEGVTPGPDNEERLAATAAGE-AEALASMPGEVEASGVA-----PGELDLSMSAQS 444 E E G PGP L A A+ PG G PG+ + A + Sbjct: 1492 GEKGERG-PPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVA 1550 Query: 445 --LGEEATVGPSSEDSLTTAAAAT-EVSLSTFEDEEASGVPTD-GLAPLTATMAPERAVT 500 GE+ VGP+ T L D G P D G LT P + Sbjct: 1551 GPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPP-GDS 1609 Query: 501 SGPGDEEDLAAATTEEPLITAGGE----ESGSPPPDGPPLPLPTVAPERWITPAQREHVG 556 PG++ D P+ G + E G P G P LP A ER + A G Sbjct: 1610 GPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGDP-GLPGKAGERGLRGAP----G 1664 Query: 557 MKGQAGPKGEKGDAGEE-LPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDL-VGSE 614 ++G G KG++GD GE+ G P SGP G G G D G G+ + + Sbjct: 1665 VRGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPP-GRLVDTGPGAREKGEPGD 1723 Query: 615 QLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGL 674 + GP GP G PGLPG PG+ G + F GPPG G+ G G G G G PG+DG +GL Sbjct: 1724 RGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGL 1783 Query: 675 PGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCT 734 G G G GPNG+ G+ GDPG GLPG G++G GP G G PG PG G PG Sbjct: 1784 DGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGK 1843 Query: 735 MGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGP 794 G + E G KGEKGD G G G D GP G RG Sbjct: 1844 NGEPGDPGED-------------------GRKGEKGDSGASGREGRD-----GPKGERGA 1879 Query: 795 PGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGL 854 PG + G +P VGPPG G PG+PG GP+G +G+TG G GL Sbjct: 1880 PGIL------------GPQGPPGLPGPVGPPG-QGFPGVPGGTGPKGDRGETGSKGEQGL 1926 Query: 855 KGEQGEKGEPGAILTED---------------------------IPL-ERLMGKKGEPGM 886 GE+G +GEPG++ D +P+ ER G KG+ G Sbjct: 1927 PGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGE 1986 Query: 887 HGAPGPMGP----------------------------KGPPGHKGEFGLPGRPGRPGL-- 916 G PG GP +GPPG G G PG+PG PGL Sbjct: 1987 QGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPG 2046 Query: 917 ----------------NGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIP 960 G KG +G+ G GPPGLPG PGPPGPPG Sbjct: 2047 RAGGVGEAGRPGERGERGEKGERGEQG--RDGPPGLPGTPGPPGPPGP------------ 2092 Query: 961 VRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLR 1020 K+ VD P G+ GE+G GL G+KGE G G QGP G Sbjct: 2093 -----KVSVDEPGP---------GLSGEQGPPGLKGAKGEPGSNGDQGPKGD-------- 2130 Query: 1021 HFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGET-VVGPQGPPG 1079 + +KG+ G+ G +G+ G G + G M+GP G PG GP G G G GPPG Sbjct: 2131 RGVPGIKGDRGEPGPRGQDGNPG-LPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPG 2189 Query: 1080 APGLPGPPG-------FGRPGDPGPPGP-----------PGPPGPPAILG--AAVALPGP 1119 APGL GP G G PG+ GPPG PGPPGP ++G + LPG Sbjct: 2190 APGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLPGQ 2249 Query: 1120 PGPPGQPGLPG 1130 G G+PG PG Sbjct: 2250 VGETGKPGAPG 2260 Score = 348 bits (894), Expect = 2e-95 Identities = 265/693 (38%), Positives = 311/693 (44%), Gaps = 110/693 (15%) Query: 486 LAPLTATMAPERAVTSGPGDEEDLAAATTEEPLITAGGEESGSPPPDGPPLPLPTVAPER 545 LAP ++ AV GP ++ ++ L TA + S + P P P P P+ Sbjct: 1203 LAPGMDSVQTFFAVDDGPSLDQAVSG------LATALCQASFTTQPR--PEPCPVYCPKG 1254 Query: 546 WITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGS 605 + +G++GQ GP G+ G LPG GP GP A A+G G+D Sbjct: 1255 --QKGEPGEMGLRGQVGPPGDPG-----LPGRTGAPGPQGPPGSATAKGERGFPGADGRP 1307 Query: 606 GSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQ 665 GS G+ PG PG PGL G PG P GP G PGE GP G G PG GQ Sbjct: 1308 GSPGRAGN-------PGTPGAPGLKGSPGLP------GPRGDPGERGPRGPKGEPGAPGQ 1354 Query: 666 PGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPP--------GKKGQAGP---- 713 GLPG KG+ G GP G G GDPG RG PG P G +G+ GP Sbjct: 1355 VIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPG 1414 Query: 714 --------PGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGS----GSTQLLNEPKLSRPTA 761 PG+ G PG PGP GP GP G + +G+ G E P Sbjct: 1415 EGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPG 1474 Query: 762 AIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPEL 821 AIG KG++G GP GE G G GPPGP G G V G P Sbjct: 1475 AIGPKGDRGFPGPLGEAGEKGER--GPPGPAGSRGLPGVAGRP------GAKGPEGPPGP 1526 Query: 822 VGPPGPDGLPGLPGFP--------GPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIP 873 G G G PG PG P GP+G KGD G G G G QGE+G PG +L D Sbjct: 1527 TGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPG 1586 Query: 874 LERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGP 933 + G +G G+ G GP G GPPG KG+ G PG PG G G G G+ G +GP Sbjct: 1587 PKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKG--DEGP 1644 Query: 934 PGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPV-DTAHPGSPELITFHGVKGEKGSW 992 PG PG PG G G ++GA P + PV + G P GE G Sbjct: 1645 PGDPGLPGKAGERG----LRGA-------PGVRGPVGEKGDQGDP---------GEDGRN 1684 Query: 993 GLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGD-------- 1044 G PGS G KGD+G GPPGPP L KGE GD+G +G +G KGD Sbjct: 1685 GSPGSSGPKGDRGEPGPPGPPGRLVDTGPGARE-KGEPGDRGQEGPRGPKGDPGLPGAPG 1743 Query: 1045 ---INGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPGFGRPGDP----GP 1097 I G GP G PG GPAG+KG+ GP G G GL G PG P P G Sbjct: 1744 ERGIEGFRGPPGPQGDPGVRGPAGEKGDR--GPPGLDGRSGLDGKPGAAGPSGPNGAAGK 1801 Query: 1098 PGPPGPPGPPAILGAAVALPGPPGPPGQPGLPG 1130 G PG G P + G LPGP GPPG PG PG Sbjct: 1802 AGDPGRDGLPGLRGEQ-GLPGPSGPPGLPGKPG 1833 Score = 348 bits (894), Expect = 2e-95 Identities = 258/643 (40%), Positives = 297/643 (46%), Gaps = 95/643 (14%) Query: 525 ESGSPP---PDGPP-LPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEE----LPG 576 E G+P P GPP LP P + P + G+ G GPKG++G+ G + LPG Sbjct: 1876 ERGAPGILGPQGPPGLPGP-------VGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPG 1928 Query: 577 PPEPSGPVG--PTAGAEAEGSGLGWGS------DVGSGSGDLVGSEQLLRGPPGPPG--- 625 G G P E +G+ + SG + + RGP G G Sbjct: 1929 ERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQG 1988 Query: 626 PPGLPGIPGKPGTDVFMGPPGSPGEDGPAG----EPGPPGPEGQPGVDGATGLPGMKGEK 681 PPG G G PG G G PG GP G E GPPGP G G G G+PG+ G Sbjct: 1989 PPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRA 2048 Query: 682 GARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFED 741 G VGE G PG RG G G++G+ G G G PG PGPPGPPGP ++ D Sbjct: 2049 GG------VGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSV-----D 2097 Query: 742 TEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGAS-IVGPPGPRGPPGHIKV 800 G G + P L A G G GD+GPKG+RG+ G G PGPRG G Sbjct: 2098 EPGPGLSGEQGPPGLK---GAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDG---- 2150 Query: 801 LSNSLINITHGFMNFSDIPELVGP---PGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGE 857 N + G P L GP PGP G G PG PG G G G G GLKGE Sbjct: 2151 --NPGLPGERGMAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGE 2208 Query: 858 QGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLN 917 GE G PG LT +G G PG G GP G G PG GE G PG PGR G + Sbjct: 2209 PGETGPPGRGLTGPTGA---VGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGAS 2265 Query: 918 GLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSP 977 G G +G PGV G PGLPGP GP G PG GA P + +P G+P Sbjct: 2266 GKDGDRGSPGV--PGSPGLPGPVGPKGEPGPT----GA----PGQAVVGLPGAKGEKGAP 2315 Query: 978 ELIT--FHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGF 1035 + G G KG GLPG +GEKG+ G G PG P GE+G KG Sbjct: 2316 GGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDP--------------GEDGQKGA 2361 Query: 1036 KGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPGF----GR 1091 G KG KGD G PG PG PGP G KG+ +G G PGAPG+ G PG G Sbjct: 2362 PGPKGFKGDPG-----VGVPGSPGPPGPPGVKGD--LGLPGLPGAPGVVGFPGQTGPRGE 2414 Query: 1092 PGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNL 1134 G PGP G G GPP G L GPPGPPG G PG+ L Sbjct: 2415 MGQPGPSGERGLAGPPGREGIPGPL-GPPGPPGSVGPPGASGL 2456 Score = 341 bits (875), Expect = 3e-93 Identities = 267/751 (35%), Positives = 313/751 (41%), Gaps = 193/751 (25%) Query: 525 ESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAG----------EEL 574 + G P P GPP L P ++ G +GQ GP+G KGD G E Sbjct: 1695 DRGEPGPPGPPGRLVDTGPGA----REKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGF 1750 Query: 575 PGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPG 634 GPP P G G A +G G D SG L G PG GP G G G Sbjct: 1751 RGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSG----------LDGKPGAAGPSGPNGAAG 1800 Query: 635 KPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKG 694 K G G PG GE G G GPPG G+PG DG GL G GE G G +G GEKG Sbjct: 1801 KAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKGEKG 1860 Query: 695 DPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGP------GCTMGLGFEDTEGS--- 745 D G G G G KG+ G PG++GP GPPG PGP GP G G G + G Sbjct: 1861 DSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGS 1920 Query: 746 -------GSTQLLNEPK---------------------------------LSRPTAAIGL 765 G L EP L P G Sbjct: 1921 KGEQGLPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGP 1980 Query: 766 KGEKGDRGPKG---------ERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFS 816 KG+ G++GP G ERG+ G G PGP+GPPG + G Sbjct: 1981 KGDSGEQGPPGKEGPIGFPGERGLKGDR--GDPGPQGPPG-----------LALGER--- 2024 Query: 817 DIPELVGPPGPDGL------PGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGE------- 863 GPPGP GL PG+PG PG G G+ G PG G +GE+GE+GE Sbjct: 2025 ------GPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGRDGPP 2078 Query: 864 -----------PGAILTEDIPLERLMGK---------KGEPGMHGAPGPMGPKGPPGHKG 903 PG ++ D P L G+ KGEPG +G GP G +G PG KG Sbjct: 2079 GLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKG 2138 Query: 904 EFGLPG------RPGRPGLNGLKGTKGDPGVIMQGPPGLPGP------PGPPGPPGAVIN 951 + G PG PG PG G+ G +G PG +QGP G PGP PGPPG PG Sbjct: 2139 DRGEPGPRGQDGNPGLPGERGMAGPEGKPG--LQGPRGPPGPVGGHGDPGPPGAPG---- 2192 Query: 952 IKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPG 1011 + G P P +T PG G+ G G+ GLPG G G G QG PG Sbjct: 2193 LAGPAGPQGPSGLKGEPGETGPPG-------RGLTGPTGAVGLPGPPGPSGLVGPQGSPG 2245 Query: 1012 PPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETV 1071 P + G +G G G++G G + GS + GP G G PGP G G+ V Sbjct: 2246 LPGQVGETGK--PGAPGRDGASGKDGDRGSPG-VPGSPGLPGPVGPKGEPGPTGAPGQAV 2302 Query: 1072 VG---PQGPPGAPG-----------------LPGPPG-------FGRPGDPGPPGPPGPP 1104 VG +G GAPG LPGP G G PGDPG G G P Sbjct: 2303 VGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAP 2362 Query: 1105 GPPAILG-AAVALPGPPGPPGQPGLPGSRNL 1134 GP G V +PG PGPPG PG+ G L Sbjct: 2363 GPKGFKGDPGVGVPGSPGPPGPPGVKGDLGL 2393 Score = 338 bits (867), Expect = 2e-92 Identities = 297/878 (33%), Positives = 359/878 (40%), Gaps = 164/878 (18%) Query: 345 AGAFLDIAEEKNLAATAAGLA-----EVPISTAGEA-----EASSVPTGGPTLSMSTENP 394 +G+FL + E + +G E PI GE P G P L++ P Sbjct: 1967 SGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGP 2026 Query: 395 EEGVTPGPDNEERLAATAAGEA--EALASMPGEVEASGVA--PGELDLSMSAQSLGEEAT 450 PGP AGE + +PG G A PGE GE+ Sbjct: 2027 -----PGPSG-------LAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGERGEQGR 2074 Query: 451 VGPSSEDSLTTAAAATEVSLSTFEDEEASGVPTDGLAPLTATMAPERAVTSGPGDEEDLA 510 GP +S DE G+ + P E G + D Sbjct: 2075 DGPPGLPGTPGPPGPPGPKVSV--DEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRG 2132 Query: 511 AATTEEPLITAGGEESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDA 570 P I E G DG P + ER + + + G++G GP G G Sbjct: 2133 V-----PGIKGDRGEPGPRGQDGNP----GLPGERGMAGPEGKP-GLQGPRGPPGPVGGH 2182 Query: 571 GEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGL- 629 G+ PGPP G GP AG + G + G L G + G PGPPGP GL Sbjct: 2183 GD--PGPPGAPGLAGP-AGPQGPSGLKGEPGETGPPGRGLTGPTGAV-GLPGPPGPSGLV 2238 Query: 630 --PGIPGKPGTDVFMGPPGSPGEDGPAGE---------------PGPPGPEGQPGVDGA- 671 G PG PG G PG+PG DG +G+ PGP GP+G+PG GA Sbjct: 2239 GPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAP 2298 Query: 672 ----TGLPGMKGEKGARG--PNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGP--- 722 GLPG KGEKGA G VGE G G+RGLPGP G+KG+AG G G PG Sbjct: 2299 GQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQ 2358 Query: 723 -----------------PGPPGPPGPGCTMG-LGFEDTEGSGSTQLLNEPKLSRPTAAIG 764 PG PGPPGP G LG G+ P + G Sbjct: 2359 KGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGA--------PGVVGFPGQTG 2410 Query: 765 LKGEKGDRGPKGERGMDGA----SIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPE 820 +GE G GP GERG+ G I GP GP GPPG + S + G Sbjct: 2411 PRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVG---- 2466 Query: 821 LVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGA------------IL 868 L GP G G PG+ G G G +G GL G PG +GE+GEKG+ G+ IL Sbjct: 2467 LPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVIL 2526 Query: 869 TEDIP--LERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDP 926 P + MG++G G+ G GP G G PG KG G PG G GL GL+G G Sbjct: 2527 GPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQ 2586 Query: 927 GVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVK 986 G G G+PG PG PG G V I+G G + G+K Sbjct: 2587 G--QPGAAGIPGDPGSPGKDG-VPGIRG------------------EKGDVGFMGPRGLK 2625 Query: 987 GEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDIN 1046 GE+G G G GEKGD+G GPPG P L KGE G+ G G+ G G Sbjct: 2626 GERGVKGACGLDGEKGDKGEAGPPGRP--------GLAGHKGEMGEPGVPGQSGAPGK-E 2676 Query: 1047 GSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPGF-GRPGDPGPPGPPGPPG 1105 G G G G PGP G +GE G +G PG G PGP G G G PGPPG GP G Sbjct: 2677 GLIGPKGDRGFDGQPGPKGDQGEK--GERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRG 2734 Query: 1106 PPAILG-------------AAVALPGPPGPPGQPGLPG 1130 P + G A +PG PG G+ G PG Sbjct: 2735 PEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPG 2772 Score = 337 bits (863), Expect = 6e-92 Identities = 294/920 (31%), Positives = 354/920 (38%), Gaps = 226/920 (24%) Query: 401 GPDNEERLAATAAGEAEALASMPGEVEASGV-----APGELDLSMSAQSLGEEATVGPSS 455 GP L + +PG G + GE L GE +V P+ Sbjct: 1884 GPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSV-PNV 1942 Query: 456 EDSLTTA---AAATEVSLSTFEDEEASGVPTDGLAPLTATMAPERAVTSGP-GDEEDLAA 511 + L TA A+A + T+++ S +P PER GP GD + Sbjct: 1943 DRLLETAGIKASALREIVETWDESSGSFLPV-----------PERR--RGPKGDSGEQGP 1989 Query: 512 ATTEEPLITAGGE----ESGSPPPDGPP-LPLPTVAPERWI-------------TPAQRE 553 E P+ G + G P P GPP L L P P + Sbjct: 1990 PGKEGPIGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAG 2049 Query: 554 HVGMKGQAGPKGEKGDAGEE----------LPGPPEPSGPVGPTAGAEAEGSGL------ 597 VG G+ G +GE+G+ GE LPG P P GP GP + G GL Sbjct: 2050 GVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGP 2109 Query: 598 ----------GWGSDVGS----------------------------GSGDLVGSE----- 614 G D G G + G E Sbjct: 2110 PGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGL 2169 Query: 615 QLLRGPPGP------PGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGE-----------P 657 Q RGPPGP PGPPG PG+ G G G G PGE GP G P Sbjct: 2170 QGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLP 2229 Query: 658 GPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVM 717 GPPGP G G G+ GLPG GE G G G G G G+RG PG PG G GP G Sbjct: 2230 GPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPK 2289 Query: 718 GPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDR----- 772 G PGP G PG G G + G + L+ EP G +GEKG+ Sbjct: 2290 GEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGE 2349 Query: 773 -------------GPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIP 819 GPKG +G G + G PGP GPPG + G P Sbjct: 2350 PGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPG---------VKGDLGLPGLPGAP 2400 Query: 820 ELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMG 879 +VG PG G G G PGP G +G G PG G+ G G G PG++ L G Sbjct: 2401 GVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPG--ASGLKG 2458 Query: 880 KKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLN------------------GLKG 921 KG+PG+ G PGP G +G PG +GE G PG+ G GL GLKG Sbjct: 2459 DKGDPGV-GLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKG 2517 Query: 922 TKGDPGVIM--------------QGPPGLPGPPGPPGPPG-----------------AVI 950 KGD VI+ +GP GL G GP G G + Sbjct: 2518 DKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLP 2577 Query: 951 NIKGAIFPIPVRPHCKMPVDTAHPGSPEL---------ITF---HGVKGEKGSWGLPGSK 998 ++G + P +P D PG + + F G+KGE+G G G Sbjct: 2578 GLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLD 2637 Query: 999 GEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLP 1058 GEKGD+G GPPG P L KGE G+ G G+ G G G G G Sbjct: 2638 GEKGDKGEAGPPGRP--------GLAGHKGEMGEPGVPGQSGAPGK-EGLIGPKGDRGFD 2688 Query: 1059 GNPGPAGQKGETVVGPQGPPGAPGLPGPPG-FGRPGDPGPPGPPGPPGPPAILGAAVALP 1117 G PGP G +GE G +G PG G PGP G G G PGPPG GP GP + G Sbjct: 2689 GQPGPKGDQGEK--GERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQK-GER 2745 Query: 1118 GPP-----GPPGQPGLPGSR 1132 GPP G PG PG PG R Sbjct: 2746 GPPGERVVGAPGVPGAPGER 2765 Score = 316 bits (809), Expect = 1e-85 Identities = 229/621 (36%), Positives = 279/621 (44%), Gaps = 109/621 (17%) Query: 533 GPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEE-------------LPGPPE 579 GPP P V P+ +P VG G+ G G G +G++ LPGP Sbjct: 2230 GPPGPSGLVGPQG--SPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVG 2287 Query: 580 PSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTD 639 P G GPT GL G L G L G PG G GLPG G+ G Sbjct: 2288 PKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGD---LVGEPGAKGDRGLPGPRGEKGEA 2344 Query: 640 VFMGPPGSPGEDGPAGEPGP--------------PGPEGQPGVDGATGLPGMKGEKGA-- 683 G PG PGEDG G PGP PGP G PGV G GLPG+ G G Sbjct: 2345 GRAGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVG 2404 Query: 684 ----RGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGF 739 GP G +G+ G G RGL GPPG++G GP +GPPGPPG GPPG G Sbjct: 2405 FPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGP---LGPPGPPGSVGPPGAS-----GL 2456 Query: 740 EDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGA-------SIVGPPGPR 792 + +G +GL G +G+RG G RG DG + GPPG R Sbjct: 2457 KGDKGD---------------PGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSR 2501 Query: 793 GPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFP 852 G G + ++ + G D ++GPPGP G G G GPRG GD G G Sbjct: 2502 GERGEKGDVGSAGLKGDKG-----DSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDN 2556 Query: 853 GLKGEQGEKGEPGAILTEDIP-LERLMGKKGEPGMHGAPGPMGPKGP---PGHKGEFGLP 908 G G++G KGEPG + +P L L+G +G+PG G PG G G PG +GE G Sbjct: 2557 GDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDV 2616 Query: 909 GRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMP 968 G G GL G +G KG G + G G G GPPG PG + KG + V P Sbjct: 2617 GFMGPRGLKGERGVKGACG--LDGEKGDKGEAGPPGRPG-LAGHKGEMGEPGV------P 2667 Query: 969 VDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKG 1028 + PG LI G KG++G G PG KG++G++G +G PG + G Sbjct: 2668 GQSGAPGKEGLI---GPKGDRGFDGQPGPKGDQGEKGERGTPG-----------IGGFPG 2713 Query: 1029 ENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPG 1088 +G+ G G G G + GP GL G G G GE VVG G PGAPG Sbjct: 2714 PSGNDGSAGPPGPPGSVGPR----GPEGLQGQKGERGPPGERVVGAPGVPGAPG-----E 2764 Query: 1089 FGRPGDPGPPGPPGPPGPPAI 1109 G G PGP GP G G A+ Sbjct: 2765 RGEQGRPGPAGPRGEKGEAAL 2785 Score = 305 bits (781), Expect = 2e-82 Identities = 222/556 (39%), Positives = 249/556 (44%), Gaps = 116/556 (20%) Query: 626 PPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARG 685 P G G PG+ G +GPPG PG G G PGP GP G G G PG G G+ G Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPG 1311 Query: 686 PNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGS 745 G+ G G PG +G PG PG +G PG GP GP G PG PG + G Sbjct: 1312 RAGNPGTPGAPGLKGSPGLPGPRGD---PGERGPRGPKGEPGAPG---------QVIGGE 1359 Query: 746 GSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSL 805 G GL G KGD GP G G G +G PGPRGPPG L + Sbjct: 1360 GP----------------GLPGRKGDPGPSGPPGPRGP--LGDPGPRGPPG----LPGTA 1397 Query: 806 INITHGFMNFSDIPELVGP------PGPDGLPGLPGFPGPRGP---------KGDT---- 846 + G P GP PG GLPGLPG PGP+GP KGD+ Sbjct: 1398 MKGDKGDRGERGPP---GPGEGGIAPGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGA 1454 Query: 847 -GLPGFPGLKGEQGEKGEPGAILTE-DIPLERLMGKKGEPGMHGAPGPMGPKG------P 898 GLPG PG GEQG +G PGAI + D +G+ GE G G PGP G +G Sbjct: 1455 PGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGR 1514 Query: 899 PGHKGEFGLPGRPGRPGLNGLKGTKGDPGVI---MQGPPGLPGPPGPPGPPGAVINIKGA 955 PG KG G PG GR G G G GDP V+ + GP G G GP GP GA ++G Sbjct: 1515 PGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGAT-GVQGE 1573 Query: 956 IFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLD 1015 P P +P D G P G+ G G G G GEKGD G GPPGP Sbjct: 1574 RGP----PGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPV-- 1627 Query: 1016 LAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKG----ETV 1071 G +G GE GEKGD GPPG PG PG AG++G V Sbjct: 1628 ---------------GPRGRDGEVGEKGD-------EGPPGDPGLPGKAGERGLRGAPGV 1665 Query: 1072 VGP------QGPPGAPGLPGPPGFGRP-GDPGPPGPPGPPGPPAILGAAV---------A 1115 GP QG PG G G PG P GD G PGPPGPPG G Sbjct: 1666 RGPVGEKGDQGDPGEDGRNGSPGSSGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRG 1725 Query: 1116 LPGPPGPPGQPGLPGS 1131 GP GP G PGLPG+ Sbjct: 1726 QEGPRGPKGDPGLPGA 1741 Score = 266 bits (679), Expect = 1e-70 Identities = 196/493 (39%), Positives = 222/493 (45%), Gaps = 96/493 (19%) Query: 653 PAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAG 712 P G+ G PG G G G G PG+ G GA GP G G G RG PG G+ G Sbjct: 1252 PKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGS-- 1309 Query: 713 PPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDR 772 PG G PG PG PG G P L P G GE+G R Sbjct: 1310 -PGRAGNPGTPGAPGLKG----------------------SPGLPGPR---GDPGERGPR 1343 Query: 773 GPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPG 832 GPKGE G G ++G GP G PG G PGP G PG Sbjct: 1344 GPKGEPGAPG-QVIGGEGP-GLPGR------------------------KGDPGPSGPPG 1377 Query: 833 LPGFPGPRGPKGDTGLPG--FPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAP 890 G G GP+G GLPG G KG++GE+G PG P G+ G PG+ G+P Sbjct: 1378 PRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIAP-----GEPGLPGLPGSP 1432 Query: 891 GPMGPKGPPGHKGEFG-----LPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGP 945 GP GP GPPG KGE G PG PG+PG G +G +G PG I GP G G PGP G Sbjct: 1433 GPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAI--GPKGDRGFPGPLGE 1490 Query: 946 PGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQG 1005 G KG P PG GV G G+ G G G G QG Sbjct: 1491 AGE----KGERGP---------------PGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQG 1531 Query: 1006 AQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGL--PGNPGP 1063 +G PG P D A + + KGE GD G G +G G + G GPPGL PG+PGP Sbjct: 1532 EKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATG-VQGE---RGPPGLVLPGDPGP 1587 Query: 1064 AGQKGET-VVGPQGPPGAPGLPGPPGF-GRPGDPGPPGPPGPPGPPAILGAAVALPGPPG 1121 G G+ +G G G PG GPPG G PG PGPPGP GP G +G GPPG Sbjct: 1588 KGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEK-GDEGPPG 1646 Query: 1122 PPGQPGLPGSRNL 1134 PG PG G R L Sbjct: 1647 DPGLPGKAGERGL 1659 Score = 208 bits (530), Expect = 3e-53 Identities = 181/547 (33%), Positives = 218/547 (39%), Gaps = 88/547 (16%) Query: 400 PGPDNEERLAATAAGEAEALASMPGEVEASGVAPGEL--DLSMSAQSLGEEATVGPSSED 457 PGP + +A+ +PG G APG L DL + G+ GP E Sbjct: 2283 PGPVGPKGEPGPTGAPGQAVVGLPGAKGEKG-APGGLAGDLVGEPGAKGDRGLPGPRGEK 2341 Query: 458 SLTTAAAATEVSLSTFEDEEASGVPTDGLAPLTATMAPERAVTSGPGDEEDLAAATTEEP 517 + +G P D PG++ A + Sbjct: 2342 G----------------EAGRAGEPGD------------------PGEDGQKGAPGPKGF 2367 Query: 518 LITAGGEESGSPPPDGPP-----LPLPTV--APERWITPAQREHVGMKGQAGPKGEKGDA 570 G GSP P GPP L LP + AP P Q G GQ GP GE+G A Sbjct: 2368 KGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLA 2427 Query: 571 G----EELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGP 626 G E +PGP P GP G A G G D G G L GP G G Sbjct: 2428 GPPGREGIPGPLGPPGPPGSVGPPGASGLK-GDKGDPGVG----------LPGPRGERGE 2476 Query: 627 PGLPGIPGKPGTDV---FMGPPGSPGEDGPAGEPG----------------PPGPEGQPG 667 PG+ G G+PG + GPPGS GE G G+ G PPGP G G Sbjct: 2477 PGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKG 2536 Query: 668 VDGATGLPGMKGEKGARGPNGSVGEKG---DPGNRGLPGPPGKKGQAGPPGVMGPPGPPG 724 G G G+ G+KG RG NG G+KG +PG++G G PG +G GP G G G PG Sbjct: 2537 DMGERGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGSAGLPGLRGLLGPQGQPGAAGIPG 2596 Query: 725 PPGPPGPGCTMGLGFE--DTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDG 782 PG PG G+ E D G L E + G KG+KG+ GP G G+ G Sbjct: 2597 DPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAG 2656 Query: 783 ASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDG---LPGLPGFPGP 839 G G G PG + G F P G G G PG+ GFPGP Sbjct: 2657 HK--GEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGP 2714 Query: 840 RGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPP 899 G G G PG PG G +G +G G P ER++G G PG G G G GP Sbjct: 2715 SGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPA 2774 Query: 900 GHKGEFG 906 G +GE G Sbjct: 2775 GPRGEKG 2781 Score = 166 bits (420), Expect = 1e-40 Identities = 132/339 (38%), Positives = 154/339 (45%), Gaps = 85/339 (25%) Query: 870 EDIPLERLMGKKGE------------------PGMHGAPGPMGPKGPPGHKGEFGLPGRP 911 E P+ G+KGE PG GAPGP GP G KGE G PG Sbjct: 1245 EPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGAD 1304 Query: 912 GRPGLNGLKGTKGDPGVI-MQGPPGLP---------GPPGPPGPPGAVINIKGAIFP-IP 960 GRPG G G G PG ++G PGLP GP GP G PGA + G P +P Sbjct: 1305 GRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLP 1364 Query: 961 VRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGS--KGEKGDQGAQGPPGP-PLDLA 1017 R P P P G G +G GLPG+ KG+KGD+G +GPPGP +A Sbjct: 1365 GRKGDPGPSGPPGPRGP-----LGDPGPRGPPGLPGTAMKGDKGDRGERGPPGPGEGGIA 1419 Query: 1018 YLRHFLNNLKGENGDK---GFKGEKGEKGDI-NGSFLMSGPPGLPGNPGP---------- 1063 L L G G + G G+KGEKGD +G+ + G PG PG GP Sbjct: 1420 PGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPK 1479 Query: 1064 -----------AGQKGETVVGPQGPPGAPGLPGPPGFGRPGDPGPPGPPGP--------- 1103 AG+KGE GP GP G+ GLPG GRPG GP GPPGP Sbjct: 1480 GDRGFPGPLGEAGEKGER--GPPGPAGSRGLPGVA--GRPGAKGPEGPPGPTGRQGEKGE 1535 Query: 1104 ---PGPPAILGAAVALP-------GPPGPPGQPGLPGSR 1132 PG PA++G AVA P GP GP G G+ G R Sbjct: 1536 PGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGER 1574 Score = 116 bits (291), Expect = 1e-25 Identities = 120/415 (28%), Positives = 134/415 (32%), Gaps = 123/415 (29%) Query: 432 APGELDLSMSAQSLGEEATVGPSSEDSLTTAAAATEVSLSTFEDEEASGVPTDGLAPLTA 491 APG + GE GPS E L + V G + L Sbjct: 2399 APGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKG 2458 Query: 492 TMAPERAVTSGPGDEEDLAAATTEEPLITAGGEESGSPPPDGPPLPLPTVAPERWIT--P 549 GP E EP I E G P +GP R +T P Sbjct: 2459 DKGDPGVGLPGPRGERG-------EPGIRG---EDGRPGQEGP----------RGLTGPP 2498 Query: 550 AQREHVGMKGQAGPKGEKGDAGEE--LPGPPEPSGPVGPTA-----GAEAEGSGLGWGSD 602 R G KG G G KGD G+ + GPP P G G G + + G D Sbjct: 2499 GSRGERGEKGDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLDGDKGPRGDNGD 2558 Query: 603 VGS----------GSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDV------------ 640 G GS L G LL GP G PG G+PG PG PG D Sbjct: 2559 PGDKGSKGEPGDKGSAGLPGLRGLL-GPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVG 2617 Query: 641 FMGP------------------------------PGSPGEDGPAGEPGPPGPEGQPGVDG 670 FMGP PG G G GEPG PG G PG +G Sbjct: 2618 FMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEG 2677 Query: 671 ATGLPGMKGEKGARGPNGSVGEKGD---PGNRGLPGPPGKKGQAGPPGVMGPPGP----- 722 G G +G G GP G GEKG+ PG G PGP G G AGPPG G GP Sbjct: 2678 LIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEG 2737 Query: 723 ---------------------------------PGPPGPPGPGCTMGLGFEDTEG 744 PGP GP G L +D G Sbjct: 2738 LQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRGEKGEAALTEDDIRG 2792 Score = 32.0 bits (71), Expect = 4.2 Identities = 19/48 (39%), Positives = 20/48 (41%), Gaps = 10/48 (20%) Query: 1090 GRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNLVTA 1137 G PG+ G G GPPG P G PG G PG G TA Sbjct: 1257 GEPGEMGLRGQVGPPGDP----------GLPGRTGAPGPQGPPGSATA 1294 >gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] Length = 1745 Score = 361 bits (927), Expect = 2e-99 Identities = 268/707 (37%), Positives = 317/707 (44%), Gaps = 123/707 (17%) Query: 525 ESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSGPV 584 E G +GPP P P R +G +G GP G G G + G P G V Sbjct: 579 EDGERGAEGPPGPTGQAGE-----PGPRGLLGPRGSPGPTGRPGVTG--IDGAPGAKGNV 631 Query: 585 GPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGP 644 GP G G GS L G + L+ G PG GPPG PGIPG PG+D GP Sbjct: 632 GPP------GEPGPPGQQGNHGSQGLPGPQGLI-GTPGEKGPPGNPGIPGLPGSD---GP 681 Query: 645 PGSPGEDGPAGEPG---------PPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGD 695 G PG +GP GE G PPG G GV G +G G++GEKG +G +G G KGD Sbjct: 682 LGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGD 741 Query: 696 ------------PGNRGLPGPPGKKGQAGPPGVMGPPGP---------PGPPGPPG-PGC 733 PG RG GP G KGQAG G GPPG PG PG PG PG Sbjct: 742 VGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGP 801 Query: 734 TMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRG 793 +GF G + E S T GL+GE+G G +GERG GA+ G PGP+G Sbjct: 802 KGSIGFPGPLGP-----IGEKGKSGKTGQPGLEGERGPPGSRGERGQPGAT--GQPGPKG 854 Query: 794 PPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGP---KGDTGLPG 850 G G P GPPG G G PG PG RG +G TG PG Sbjct: 855 DVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQTGPPG 914 Query: 851 FPGLKGEQGEKGEPGAILTEDIP----------LERLMGKKGEPGMHGAPGPMGPKGPPG 900 G+ G QG+ GE G + P L L G++G G G PGP+G +GP G Sbjct: 915 PAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAG 974 Query: 901 HKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAV-----INIKGA 955 +G G G PG PG GLKG KG PG + G G PG GP GP G + +G Sbjct: 975 LRGFPGPKGGPGDPGPTGLKGDKGPPGPV--GANGSPGERGPLGPAGGIGLPGQSGSEGP 1032 Query: 956 IFPI----------PVRPHCK--MPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGD 1003 + P P P K +P G P G +G+KG G PG KG KGD Sbjct: 1033 VGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGD 1092 Query: 1004 QGAQGPPGPPLDLAYLRH----FLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPG 1059 +G GPPG P H + +G G G G+KG+ G + G + GPPGL G Sbjct: 1093 KGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDG-VRGFVGVIGPPGLQG 1151 Query: 1060 NPGPAGQKGET-------------VVGPQGPPGAPGLPG-PPGFGRPG------------ 1093 PGP G+KGE GPQGP G+ G PG P G G+PG Sbjct: 1152 LPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAG 1211 Query: 1094 DPGPPGPPGPPGPPAILG-----AAVALPGPPGPPGQPGLPGSRNLV 1135 DPGPPG PG PGP +G GPPG G PG G++ V Sbjct: 1212 DPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSV 1258 Score = 356 bits (913), Expect = 1e-97 Identities = 370/1230 (30%), Positives = 480/1230 (39%), Gaps = 225/1230 (18%) Query: 63 GFPAYSFGPGANVGRPARTLIPSTFF-RDFAISVVVKPSSTRGGVLFAITDAFQKVIYLG 121 G A+ G + +G P L P F +F++ + ++ VL +I D G Sbjct: 61 GDRAFRIGQASTLGIPTWELFPEGHFPENFSLLITLRGQPANQSVLLSIYDE------RG 114 Query: 122 LRLSGVEDGHQRIILYYTEPGSHVSQEAAAFSVPVMTHRWNRFAMIVQGEEVTLLVNCEE 181 R G+ G +L +P + Q+ V + RW+R A+ + GE VTL+ +CE Sbjct: 115 ARQLGLALGPALGLL--GDPFRPLPQQ-----VNLTDGRWHRVAVSIDGEMVTLVADCEA 167 Query: 182 HSRIPFQRSSQALAFESSAGIFMGNAGATGLERFTGSLQQLTVHPDPRTPEELCD---PE 238 + F S AG+ + G + F G +Q+L + PDP+ + C+ P+ Sbjct: 168 QPPV----LGHGPRFISIAGLTVLGTQDLGEKTFEGDIQELLISPDPQAAFQACERYLPD 223 Query: 239 -ESSASGETSGLQ----------EADGVAEILEAVTYTQASPKEAKVEPINTPPTPSSPF 287 ++ A T Q + G + K ++ + PP + Sbjct: 224 CDNLAPAATVAPQGEPETPRPRRKGKGKGRKKGRGRKGKGRKKNKEIWTSSPPPDSAENQ 283 Query: 288 EDMELSGEPVPEGTLETTNMSIIQHSSPKQGSGEILNDTLEGVHSVDGDPITDSGS--GA 345 ++ P L T ++ S+ G LN T+ S+D D T+ G+ Sbjct: 284 TSTDIPKTETPAPNLPPTPTPLVVTSTVTTG----LNATILE-RSLDPDSGTELGTLETK 338 Query: 346 GAFLDIAEEKNLAATAAGLAEVPIST-------AGEAEASSVPT--------GGPTLSMS 390 A D + + AE P T AGE A P GP Sbjct: 339 AAREDEEGDDSTMGPDFRAAEYPSRTQFQIFPGAGEKGAKGEPAVIEKGQQFEGPP---G 395 Query: 391 TENPEEGVTP-GPDNEERLAATAAGEAEA-LASMPGEVEASGVAPGELDLSMSAQSLGEE 448 P+ V P GP A L +PG ++ PG + + M Q G Sbjct: 396 APGPQGVVGPSGPPGPPGFPGDPGPPGPAGLPGIPG-IDGIRGPPGTV-IMMPFQFAGGS 453 Query: 449 ATVGPSSEDSLTTAAAATEVSLSTFEDEEASGVPTDGLAPLTATMAPERAVTSGPGDEED 508 P S A + LS G P G LT P + PG + + Sbjct: 454 FKGPPVSFQQAQAQAVLQQTQLSM------KGPP--GPVGLTGRPGPV-GLPGHPGLKGE 504 Query: 509 LAAATTEEPLITAGGEESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKG 568 A + P G P GPP + + P G+ G GPKG++G Sbjct: 505 EGAEGPQGP--------RGLQGPHGPPGRVGKMG-----RPGADGARGLPGDTGPKGDRG 551 Query: 569 -DAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPP 627 D LPG G G G G++ G G GP G GP Sbjct: 552 FDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEP----GPRGLLGPR 607 Query: 628 GLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPN 687 G PG G+PG G PG+ G GP GEPGPPG +G G G G G+ G G +GP Sbjct: 608 GSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTPGEKGPP 667 Query: 688 GSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGS-- 745 G+ G G PG+ G G PG +G G G GPPG GPPG PGP G + T G+ Sbjct: 668 GNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGP-----RGVKGTSGNRG 722 Query: 746 --GSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSN 803 G E +GLKG++G G G RG D GP GP+G G Sbjct: 723 LQGEKGEKGEDGFPGFKGDVGLKGDQGKPGAPGPRGED-----GPEGPKGQAGQAGEEGP 777 Query: 804 SLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGE------ 857 G + +P G PGP G G PG GP G KG +G G PGL+GE Sbjct: 778 PGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGS 837 Query: 858 QGEKGEPGA---------ILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLP 908 +GE+G+PGA + + P + G+KG PG+ G PG GPKGPPGH+G+ G P Sbjct: 838 RGERGQPGATGQPGPKGDVGQDGAP--GIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRP 895 Query: 909 GRPGRPGLNGLKGTKGDPGVI----------MQGPPGLPGPPGPPGPPG-----AVINIK 953 G PG+ G G +G G PG GP G GPPGPPGPPG + + Sbjct: 896 GHPGQRGELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGRE 955 Query: 954 GAIFPI-PVRPHCK--------MPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGE---- 1000 GA + P P K P PG P G KG G G GS GE Sbjct: 956 GAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPL 1015 Query: 1001 -----------------------KGDQGAQGPPGP------PLDLAYL-RHFLNNLKGEN 1030 KG +G +GPPGP P L L GE Sbjct: 1016 GPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEE 1075 Query: 1031 GDK------GFKGEKGEKGD--------INGSFLMSGPPGLP------GNPGPAGQKGET 1070 GDK G KG KG+KGD I G GPPG G PG GQKG+ Sbjct: 1076 GDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDD 1135 Query: 1071 ----VVGPQGPPGAPGLPGPPG----------FGRPGDPGPPGPPGP------PGPPAIL 1110 VG GPPG GLPGPPG G G PGP GP GP PG P + Sbjct: 1136 GVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGV 1195 Query: 1111 GAAVAL--------PGPPGPPGQPGLPGSR 1132 G A+ G PGPPG PG+PG + Sbjct: 1196 GQPGAVGEKGERGDAGDPGPPGAPGIPGPK 1225 Score = 355 bits (912), Expect = 1e-97 Identities = 267/686 (38%), Positives = 317/686 (46%), Gaps = 144/686 (20%) Query: 525 ESGSPPPDGPP-LPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAG-EELPGPPEPSG 582 E G P GPP P P P H G G+ G G++G+ G + GPP P+G Sbjct: 867 EKGLPGLQGPPGFPGPKGPPG---------HQGKDGRPGHPGQRGELGFQGQTGPPGPAG 917 Query: 583 PVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPG---LPGIPGKPGTD 639 +GP G E LG RGPPGPPGPPG LPG+ G+ G Sbjct: 918 VLGPQ-GKTGEVGPLGE------------------RGPPGPPGPPGEQGLPGLEGREGAK 958 Query: 640 VFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGD---P 696 +GPPG G++GPAG G PGP+G PG G TGL G KG G G NGS GE+G Sbjct: 959 GELGPPGPLGKEGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPA 1018 Query: 697 GNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPG----PGCTMGLGFEDTEGSGSTQLLN 752 G GLPG G +G GP G G G GPPGP G PG LG G + + Sbjct: 1019 GGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEG-D 1077 Query: 753 EPKLSRPTAAIGLKGEKGDRGPKGERGMDG-ASIVGPPGP------RGPPGHIKVLSNSL 805 + + P G KG+KGD GP G+ G+ G A GPPG RGPPG + Sbjct: 1078 KGDVGAPGHK-GSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDG 1136 Query: 806 INITHGFMNFSDIPELVGPPGPDGLPGLPG---------------FPGPRGPKGDTGLPG 850 + GF+ ++GPPG GLPG PG PGPRGP+G TG G Sbjct: 1137 VR---GFVG------VIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEG 1187 Query: 851 FPGL------------KGEQGEKGEPGAILTEDIPLERL-MGKKGEPGMHGAPGPMGPKG 897 PGL KGE+G+ G+PG IP + +G+KG+ G GA GP G KG Sbjct: 1188 TPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKG 1247 Query: 898 PPGHKG------------EFGLPGRPGRPGLNGLKGTKGDPGVIM-QGPPGLPGPPGPPG 944 PPG G + G PG PG G++G G KGDPG + GPPG G PG PG Sbjct: 1248 PPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPG 1307 Query: 945 PPG--------------AVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKG 990 PPG KG P P P + A G P + G++G G Sbjct: 1308 PPGKRGPSGHMGREGREGEKGAKGE--PGPDGPPGRTGPMGAR-GPPGRVGPEGLRGIPG 1364 Query: 991 SWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFL 1050 G PG G G G GP GP + L G GD G KGEKG G I Sbjct: 1365 PVGEPGLLGAPGQMGPPGPLGP-----------SGLPGLKGDTGPKGEKGHIGLI----- 1408 Query: 1051 MSGPPGLPGNPGPAGQKGET-VVGPQGPPGAPGLPGPPG-FGRPGDPGPPGPPGPPGPPA 1108 GL G PG AG+KG+ + G QGPPG G PGPPG G G PGPPG GP G Sbjct: 1409 -----GLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKG 1463 Query: 1109 ILGAAVAL-----PGPPGPPGQPGLP 1129 G+ ++ GP GPPG PG P Sbjct: 1464 SKGSPGSMGPRGDTGPAGPPGPPGAP 1489 Score = 338 bits (868), Expect = 2e-92 Identities = 264/695 (37%), Positives = 305/695 (43%), Gaps = 121/695 (17%) Query: 503 PGDEEDLAAATTEEPLITAGGE-ESGSPPPDGPPLP--LPTVAPERWITPAQREH----- 554 PG + L E P G + GS P G P P + + R + + E Sbjct: 676 PGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGVKGTSGNRGLQGEKGEKGEDGF 735 Query: 555 VGMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSE 614 G KG G KG++G G PGP GP GP A G GS G + G Sbjct: 736 PGFKGDVGLKGDQGKPGA--PGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKGKLGVPG-- 791 Query: 615 QLLRGPPGPPGPPGLPGIPG---------------KPGTDVFMGPPGSPGEDGPAGEPGP 659 L G PG PGP G G PG +PG + GPPGS GE G G G Sbjct: 792 --LPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGERGQPGATGQ 849 Query: 660 PGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGP 719 PGP+G G DGA G+PG KG G +GP G G KG PG++G G PG GQ G G G Sbjct: 850 PGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRGELGFQGQ 909 Query: 720 PGPPGPP---------------------GPPGPGCTMGL-GFEDTEGS------------ 745 GPPGP GPPGP GL G E EG+ Sbjct: 910 TGPPGPAGVLGPQGKTGEVGPLGERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGK 969 Query: 746 -GSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNS 804 G L P G G KGD+GP G G +G+ G GP GP G I + S Sbjct: 970 EGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSP--GERGPLGPAGGIGLPGQS 1027 Query: 805 LINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEP 864 G GPPGP G G+PG GP GP PG G GE+G+KG+ Sbjct: 1028 GSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGPLGP------PGAAGPSGEEGDKGDV 1081 Query: 865 GAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKG 924 GA P + G KG+ G G PG G +GP GH G G G GR G GL G KG Sbjct: 1082 GA------PGHK--GSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKG 1133 Query: 925 DPGVI----MQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELI 980 D GV + GPPGL G PGPPG G V ++ + PH P P+ Sbjct: 1134 DDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGS------MGPH-----GAPGPRGPQGP 1182 Query: 981 T-FHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEK 1039 T G G G G PG+ GEKG++G G PGPP G G G KG+ Sbjct: 1183 TGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPP--------------GAPGIPGPKGDI 1228 Query: 1040 GEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPGF----GRPGDP 1095 GEKGD +G +GPPG G PG G KG VGP G PG G PG PG G PG+ Sbjct: 1229 GEKGD-SGPSGAAGPPGKKGPPGEDGAKGS--VGPTGLPGDLGPPGDPGVSGIDGSPGEK 1285 Query: 1096 GPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPG 1130 G PG G PGPP G PG PGPPG+ G G Sbjct: 1286 GDPGDVGGPGPPGASGE----PGAPGPPGKRGPSG 1316 Score = 298 bits (764), Expect = 2e-80 Identities = 216/572 (37%), Positives = 260/572 (45%), Gaps = 121/572 (21%) Query: 533 GPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEE-LPGPPEPSGPVGPTAGAE 591 GPP PL P G++G GPKG GD G L G P GPVG G+ Sbjct: 962 GPPGPLGKEGP-----------AGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGAN-GSP 1009 Query: 592 AEGSGLGWGSDVG----SGSGDLVG--SEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPP 645 E LG +G SGS VG ++ RG GPPGP G GIPG G +GPP Sbjct: 1010 GERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLGP---LGPP 1066 Query: 646 GS---------------PGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGA---RGPN 687 G+ PG G G+ G GP GQPG+ G G PG G GA RGP Sbjct: 1067 GAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPP 1126 Query: 688 GSVGEKGD------------PGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGP---- 731 G G+KGD PG +GLPGPPG+KG+ G G MGP G PGP GP GP Sbjct: 1127 GLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSE 1186 Query: 732 ---GCTMGLGFEDTEGS-GSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVG 787 G G+G G G +P P A G+ G KGD G KG+ G GA+ G Sbjct: 1187 GTPGLPGGVGQPGAVGEKGERGDAGDPG---PPGAPGIPGPKGDIGEKGDSGPSGAA--G 1241 Query: 788 PPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTG 847 PPG +GPPG + G + + +P +GPPG G+ G+ G PG +G GD G Sbjct: 1242 PPGKKGPPGE---------DGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVG 1292 Query: 848 LPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGL 907 PG PG GE G G PG MG++G G GA G GP GPPG G G Sbjct: 1293 GPGPPGASGEPGAPGPPGKRGPSGH-----MGREGREGEKGAKGEPGPDGPPGRTGPMGA 1347 Query: 908 PGRPGR---PGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPH 964 G PGR GL G+ G G+PG++ G PG GPPGP GP G + +KG P + H Sbjct: 1348 RGPPGRVGPEGLRGIPGPVGEPGLL--GAPGQMGPPGPLGPSG-LPGLKGDTGPKGEKGH 1404 Query: 965 CKM-----------------------------------PVDT-AHPGSPELITFHGVKGE 988 + P+ + HPG P + G KG Sbjct: 1405 IGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGS 1464 Query: 989 KGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLR 1020 KGS G G +G+ G G GPPG P +L LR Sbjct: 1465 KGSPGSMGPRGDTGPAGPPGPPGAPAELHGLR 1496 Score = 281 bits (719), Expect = 3e-75 Identities = 206/524 (39%), Positives = 238/524 (45%), Gaps = 88/524 (16%) Query: 488 PLTATMAPERAVTSGPGDEEDLAAATTEEPLITAGGE-----ESGSPPP---DGPPLPLP 539 P+ A +P GP L + E + G+ E G P P DG P PL Sbjct: 1002 PVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTGKDGIPGPLG 1061 Query: 540 TVAPERWITPAQRE----HVGMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGS 595 + P P+ E VG G G KG+KGDAG PG P GP G A+G+ Sbjct: 1062 PLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGP--PGQPGIRGPAGHPGPPGADGA 1119 Query: 596 -------GLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSP 648 GL +G G VG + GPPG G PG PG G+ G MGP G+P Sbjct: 1120 QGRRGPPGL-FGQKGDDGVRGFVG----VIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAP 1174 Query: 649 GEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARG---------------PNGSVGEK 693 G P G GP G EG PG+ G G PG GEKG RG P G +GEK Sbjct: 1175 G---PRGPQGPTGSEGTPGLPGGVGQPGAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEK 1231 Query: 694 GDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGL-GFEDTEG-------- 744 GD G G GPPGKKG G G G GP G PG GP G+ G + + G Sbjct: 1232 GDSGPSGAAGPPGKKGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDV 1291 Query: 745 --------SGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGA-SIVGPPGPRGPP 795 SG P P+ +G +G +G++G KGE G DG GP G RGPP Sbjct: 1292 GGPGPPGASGEPGAPGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPP 1351 Query: 796 GHIKVLSNSLINITHGFMNFSDIPE-LVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGL 854 G + PE L G PGP G PGL G PG GP G G G PGL Sbjct: 1352 GRVG-------------------PEGLRGIPGPVGEPGLLGAPGQMGPPGPLGPSGLPGL 1392 Query: 855 KGEQGEKGEPGAI-LTEDIPLERLMGKKGE---PGMHGAPGPMGPKGPPGHKGEFGLPGR 910 KG+ G KGE G I L I G+KG+ PG+ G PGP G GPPG G G PG Sbjct: 1393 KGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGP 1452 Query: 911 PGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKG 954 PG G G KG+KG PG GP G GP GPPGPPGA + G Sbjct: 1453 PGVAGPLGQKGSKGSPG--SMGPRGDTGPAGPPGPPGAPAELHG 1494 Score = 198 bits (504), Expect = 3e-50 Identities = 169/536 (31%), Positives = 203/536 (37%), Gaps = 119/536 (22%) Query: 662 PEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAG---PPGVMG 718 P+G+P KG K RG G +K P P + Q P Sbjct: 235 PQGEPETPRPRRKGKGKGRKKGRGRKGKGRKKNKEIWTSSPPPDSAENQTSTDIPKTETP 294 Query: 719 PPGPPGPPGP---------------------PGPGCTMGL-----GFEDTEGSGSTQLLN 752 P P P P P G +G ED EG ST + Sbjct: 295 APNLPPTPTPLVVTSTVTTGLNATILERSLDPDSGTELGTLETKAAREDEEGDDSTMGPD 354 Query: 753 EPKLSRPTAA-IGLKGEKGDRGPKGERGM--DGASIVGPPGPRGPPGHIKVLSNSLINIT 809 P+ + G++G KGE + G GPPG GP G Sbjct: 355 FRAAEYPSRTQFQIFPGAGEKGAKGEPAVIEKGQQFEGPPGAPGPQG------------- 401 Query: 810 HGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGE--------- 860 +VGP GP G PG PG PGP GP G G+PG G++G G Sbjct: 402 -----------VVGPSGPPGPPGFPGDPGPPGPAGLPGIPGIDGIRGPPGTVIMMPFQFA 450 Query: 861 ----KGEPGAIL---TEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGR 913 KG P + + + + + KG PG G G GP G PGH G G G G Sbjct: 451 GGSFKGPPVSFQQAQAQAVLQQTQLSMKGPPGPVGLTGRPGPVGLPGHPGLKGEEGAEGP 510 Query: 914 PGLNGLKGTKGDPGVI-MQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTA 972 G GL+G G PG + G PG G G PG G KG D Sbjct: 511 QGPRGLQGPHGPPGRVGKMGRPGADGARGLPGDTGP----KG---------------DRG 551 Query: 973 HPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGD 1032 G P L G +G+ G G PG GE G++GA+GPPGP GE G Sbjct: 552 FDGLPGLPGEKGQRGDFGHVGQPGPPGEDGERGAEGPPGP-----------TGQAGEPGP 600 Query: 1033 KGFKGEKGEKGDIN--GSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPGF- 1089 +G G +G G G + G PG GN GP G+ G G QG G+ GLPGP G Sbjct: 601 RGLLGPRGSPGPTGRPGVTGIDGAPGAKGNVGPPGEPGPP--GQQGNHGSQGLPGPQGLI 658 Query: 1090 GRPGDPGPPGPPGPPGPPAILG-----------AAVALPGPPGPPGQPGLPGSRNL 1134 G PG+ GPPG PG PG P G GPPG G PG PG R + Sbjct: 659 GTPGEKGPPGNPGIPGLPGSDGPLGHPGHEGPTGEKGAQGPPGSAGPPGYPGPRGV 714 Score = 142 bits (359), Expect = 2e-33 Identities = 120/380 (31%), Positives = 154/380 (40%), Gaps = 53/380 (13%) Query: 363 GLAEVPISTAGEAEASSVPTGGPTLSMSTENPE-----EGVTPG-PDNEERLAATAAGEA 416 GL +P + E V + GP + P+ EG TPG P + A Sbjct: 1148 GLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEG-TPGLPGGVGQPGAVGEKGE 1206 Query: 417 EALASMPGEVEASGVAPGELDLSMSAQS-----LGEEATVGPSSEDSLTTAAAATEVSLS 471 A PG A G+ + D+ S G GP ED + T Sbjct: 1207 RGDAGDPGPPGAPGIPGPKGDIGEKGDSGPSGAAGPPGKKGPPGEDGAKGSVGPT----- 1261 Query: 472 TFEDEEASGVPTDGLAPLTATMAPERAVTSGPGDEEDLAAATTEEPLITAGGEESGSPPP 531 G+P D P ++ + PG++ D P +G E G+P P Sbjct: 1262 --------GLPGDLGPPGDPGVS---GIDGSPGEKGDPGDVGGPGPPGASG--EPGAPGP 1308 Query: 532 DGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAE 591 G P H+G +G+ G KG KG+ G + GPP +GP+G Sbjct: 1309 PGKRGP--------------SGHMGREGREGEKGAKGEPGPD--GPPGRTGPMGARGPPG 1352 Query: 592 AEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGED 651 G G G L+G+ + GPPGP GP GLPG+ G G P G G Sbjct: 1353 RVGPEGLRGIPGPVGEPGLLGAPGQM-GPPGPLGPSGLPGLKGDTG------PKGEKGHI 1405 Query: 652 GPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQA 711 G G GPPG G+ G G G+ G G KG GP G +G G PG G+ GP G+KG Sbjct: 1406 GLIGLIGPPGEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGHPGPPGVAGPLGQKGSK 1465 Query: 712 GPPGVMGPPGPPGPPGPPGP 731 G PG MGP G GP GPPGP Sbjct: 1466 GSPGSMGPRGDTGPAGPPGP 1485 >gi|116256356 alpha 4 type IV collagen precursor [Homo sapiens] Length = 1690 Score = 359 bits (922), Expect = 9e-99 Identities = 263/697 (37%), Positives = 306/697 (43%), Gaps = 166/697 (23%) Query: 522 GGEESGSPP-PDGPPLPLPTVAPERWIT----------PAQREHVGMKGQAGPKGEKGDA 570 GGE+ SP P GPP P V ++ I P +R G+ G GP+G+ G Sbjct: 733 GGEKGSSPVGPPGPP-GSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCP 791 Query: 571 GEE----LPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLL--------- 617 G E +PG GP G A G G G+ + G L Sbjct: 792 GAEGPAGIPGFLGLKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAP 851 Query: 618 --RGPPG---PPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGAT 672 +G PG PPGP G+ G+PG PG GPPG PG GP G+ G PGP G G G Sbjct: 852 GGKGQPGDVGPPGPAGMKGLPGLPGRPGAHGPPGLPGIPGPFGDDGLPGPPGPKGPRGLP 911 Query: 673 GLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPP------------ 720 G PG GE+G G G G KG+PG +G+ G PG +G G G +GPP Sbjct: 912 GFPGFPGERGKPGAEGCPGAKGEPGEKGMSGLPGDRGLRGAKGAIGPPGDEGEMAIISQK 971 Query: 721 GPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGP----KG 776 G PG PGPPG GF G T + G +GE G GP +G Sbjct: 972 GTPGEPGPPGDD-----GFPGERGDKGTPGMQ-----------GRRGEPGRYGPPGFHRG 1015 Query: 777 ERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGF 836 E G G GPPGP GPPG + GF+ F +P G PG G PG G Sbjct: 1016 EPGEKGQP--GPPGPPGPPGSTGL---------RGFIGFPGLPGDQGEPGSPGPPGFSGI 1064 Query: 837 PGPRGPKGDTGLP----GFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGP 892 G RGPKG+ G P G PG KGE G G PG G++G PG+ G G Sbjct: 1065 DGARGPKGNKGDPASHFGPPGPKGEPGSPGCPGHF--------GASGEQGLPGIQGPRGS 1116 Query: 893 MGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINI 952 G GPPG G G PG G PGL G G GDP GP GL G PG PGPPG I Sbjct: 1117 PGRPGPPGSSGPPGCPGDHGMPGLRGQPGEMGDP-----GPRGLQGDPGIPGPPG----I 1167 Query: 953 KGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGS--------------WGLPGSK 998 KG GSP L HG+KG+KG+ G+PG K Sbjct: 1168 KGP------------------SGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIPGLK 1209 Query: 999 GEKGDQGAQG--PPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPG 1056 GE+GD G+ G PPGP +G+ G G G G G + P Sbjct: 1210 GERGDPGSPGISPPGP--------------RGKKGPPGPPGSSGPPGPAGAT--GRAPKD 1253 Query: 1057 LPGNPGPAGQKGETVVGPQGPPGAPGLPGPPGF-----GRPGD---PGPPGPPGPPGPPA 1108 +P +PGP G +G GP GP GAPG PG PG G PGD PGPPGPPGPPGPP Sbjct: 1254 IP-DPGPPGDQGPP--GPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPG 1310 Query: 1109 ILG-----------AAVALPGPPGPPGQPGLPGSRNL 1134 G V PGP GP G PG PG + L Sbjct: 1311 YKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGL 1347 Score = 351 bits (901), Expect = 2e-96 Identities = 267/691 (38%), Positives = 313/691 (45%), Gaps = 125/691 (18%) Query: 527 GSPPPDGPPLPLPTVAPERWI------TPAQREHVGMKGQAGPKGEKGDAGEEL------ 574 G P P G P LP + E I P + G G G G +G G + Sbjct: 405 GPPGPQGFP-GLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVG 463 Query: 575 -PGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIP 633 PGP G VGP G +G G+E L PGP GPPG PG+P Sbjct: 464 NPGPQGIKGKVGPPGGRGPKGEK---------------GNEGLCACEPGPMGPPGPPGLP 508 Query: 634 GKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPG------------MKGEK 681 G+ G+ +G PG G G G PG GP G PG GA+G PG +KG K Sbjct: 509 GRQGSKGDLGLPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHK 568 Query: 682 GARGPNGSVGEKGDPGNRGLPGPPGKKGQAGP--------PGVMGPPGPPGPPGPPGPGC 733 G RGP+G G G PG+ G G G+KG GP PG G PGP GPPG GP Sbjct: 569 GERGPDGPPGFPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVG 628 Query: 734 TMGLGFEDTEGS-GSTQLLNEPKLSRPTAAIGLKGEKGDR--------GPKGERGMDG-A 783 GLGF G G + P + P GLKG+KGD G G G DG Sbjct: 629 PPGLGFPGPPGERGHPGVPGHPGVRGPD---GLKGQKGDTISCNVTYPGRHGPPGFDGPP 685 Query: 784 SIVGPPGPRGPP---------GHIKVLSNSLINITHGFMNFSDIPEL--------VGPPG 826 G PGP+G P G + I GF P VGPPG Sbjct: 686 GPKGFPGPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPG 745 Query: 827 PDGLP------GLPGFP--GPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIP----L 874 P G P G+PG P G GP G GL G PG+KG +G+ G PGA IP L Sbjct: 746 PPGSPGVNGQKGIPGDPAFGHLGPPGKRGLSGVPGIKGPRGDPGCPGAEGPAGIPGFLGL 805 Query: 875 ERLMGKKGEPGMHGAPGPMG---PKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPG---- 927 + G++G G G PGP G +G PG G+ GLPG PG PG G KG GD G Sbjct: 806 KGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGSPGAPGGKGQPGDVGPPGP 865 Query: 928 VIMQGPPGLPGPPGPPGPPGAVINIKGAIFP--IPVRPHCKMPVDTAHPGSPELITFHGV 985 M+G PGLPG PG GPPG + I G +P P K P G P F G Sbjct: 866 AGMKGLPGLPGRPGAHGPPG-LPGIPGPFGDDGLPGPPGPKGP-----RGLPGFPGFPGE 919 Query: 986 KGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDI 1045 +G+ G+ G PG+KGE G++G G PG L+G G G G++GE I Sbjct: 920 RGKPGAEGCPGAKGEPGEKGMSGLPGD-----------RGLRGAKGAIGPPGDEGEMAII 968 Query: 1046 N--GSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPGF--GRPGDPGPPGPP 1101 + G+ GPPG G PG G KG G QG G PG GPPGF G PG+ G PGPP Sbjct: 969 SQKGTPGEPGPPGDDGFPGERGDKG--TPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPP 1026 Query: 1102 GPPGPPAILG--AAVALPGPPGPPGQPGLPG 1130 GPPGPP G + PG PG G+PG PG Sbjct: 1027 GPPGPPGSTGLRGFIGFPGLPGDQGEPGSPG 1057 Score = 335 bits (859), Expect = 2e-91 Identities = 251/668 (37%), Positives = 289/668 (43%), Gaps = 182/668 (27%) Query: 566 EKGDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPG 625 EKG G PGPP P GP+GP LG +G + E+ +RG GPPG Sbjct: 60 EKGSRGP--PGPPGPQGPIGP----------LGAPGPIG------LSGEKGMRGDRGPPG 101 Query: 626 PPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGV---DGATGLPGMKGEKG 682 G G G G PG PG DG G PGPPGP G+PG+ +G+ G PG G +G Sbjct: 102 AAGDKGDKGPTGV------PGFPGLDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRG 155 Query: 683 ARGPNGSV---GEKGDPGNR-----------------GLPGPPGKKGQAGPPGVMGPPGP 722 A GP G + GEKG+ GN GLPG PG G GP G G PG Sbjct: 156 ALGPGGPLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGE 215 Query: 723 PGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDG 782 PG GPPG GL + +G+KG+ GD G G++G G Sbjct: 216 PGLVGPPGQPGRPGL--------------------KGNPGVGVKGQMGDPGEVGQQGSPG 255 Query: 783 AS-IVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGL----------- 830 + +V PP + G IP +VG PGP G Sbjct: 256 PTLLVEPPD---------------FCLYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGE 300 Query: 831 PGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAP 890 G+PGFPGPRG G G PGFPGLKGE G G+PG L L+G KG+PG G P Sbjct: 301 KGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPG--------LFGLIGPKGDPGNRGHP 352 Query: 891 GP-----------MGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGP 939 GP GP G PG G +G G G PG GL G G+ M GPPG G Sbjct: 353 GPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQGF 412 Query: 940 PGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITF---------------HG 984 PG PG PG I G P +P P PG+P L G Sbjct: 413 PGLPGLPGEA-GIPGRPDSAPGKP--GKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQG 469 Query: 985 VKGEKGSWGLPGSKGEKGDQ-------GAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKG 1037 +KG+ G G G KGEKG++ G GPPGPP L +G GD G G Sbjct: 470 IKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPP--------GLPGRQGSKGDLGLPG 521 Query: 1038 EKGEKGDINGSFLMSGPPGLPGN------PGPAGQKGETVV----------GPQGPPGAP 1081 G KGD G GPPGLPG PG G KG+ VV GP GPPG P Sbjct: 522 WLGTKGD-PGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPGFP 580 Query: 1082 GLPGPPG----FGRPGDPGPPGP-----------PGPPGPPAILG----AAVALPGPPGP 1122 G PG G G GDPGPPG PGP GPP G + PGPPG Sbjct: 581 GQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGE 640 Query: 1123 PGQPGLPG 1130 G PG+PG Sbjct: 641 RGHPGVPG 648 Score = 333 bits (853), Expect = 9e-91 Identities = 263/673 (39%), Positives = 304/673 (45%), Gaps = 137/673 (20%) Query: 556 GMKGQAGPKGEKGDAG------EELPGPPEPSGPVGP--TAGAEAEGSGLGWGSDVG--- 604 GM G GP G KG++G + +PG P P G G + G LG D G Sbjct: 279 GMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSYGSPGFPGLKGELGLVGDPGLFG 338 Query: 605 --------------SGSGDLVGSEQLLRGPP---------------GPPGPPGLPGIPGK 635 G LV L+GPP GPPGPPGL G PG+ Sbjct: 339 LIGPKGDPGNRGHPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGE 398 Query: 636 --------PGTDVFMGPPGSPGEDG----PAGEPGPPGPEGQPGVDGATGLPGMKGEK-- 681 PG F G PG PGE G P PG PG G PG+ GA GL G+ G Sbjct: 399 ACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVI 458 Query: 682 ----GARGPNGSVGEKGDPGNRGLPGPPGKKGQ-AGPPGVMGPPGPPGPPGPPGPGCTMG 736 G GP G G+ G PG RG G G +G A PG MGPPGPPG PG G +G Sbjct: 459 YCSVGNPGPQGIKGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLG 518 Query: 737 L-GFEDTEGS----GSTQLLNEPKLSRPTAAIGLKGEKGD------RGPKGERGMDG-AS 784 L G+ T+G G+ P + G KG KGD +G KGERG DG Sbjct: 519 LPGWLGTKGDPGPPGAEGPPGLPGKHGASGPPGNKGAKGDMVVSRVKGHKGERGPDGPPG 578 Query: 785 IVGPPGPRGPPGHIKVLSN-----SLINITHGFMNFSDIPELVGPP---GPDGLPGLPGF 836 G PG G GH + + T G F P +GPP GP G PGL GF Sbjct: 579 FPGQPGSHGRDGHAGEKGDPGPPGDHEDATPGGKGF---PGPLGPPGKAGPVGPPGL-GF 634 Query: 837 PGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPM--- 893 PGP G +G G+PG PG++G G KG+ G ++ ++ G+ G PG G PGP Sbjct: 635 PGPPGERGHPGVPGHPGVRGPDGLKGQKGDTISCNVTYP---GRHGPPGFDGPPGPKGFP 691 Query: 894 GPKGPPGHKGEFGLPGRPGRPGL------NGLKGTKGDPGVIMQGPPGLPGPPGPPGPPG 947 GP+G PG G G GRPG PG G +G GDPG + GPPGPPG PG Sbjct: 692 GPQGAPGLSGSDGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPG 751 Query: 948 AVINIKGAIFPIPVRPHCKMPVDTA--HPGSPELITFHGVKGEKGSWGLPGSKGEKGDQG 1005 V KG +P D A H G P G++G G+PG KG +GD G Sbjct: 752 -VNGQKG------------IPGDPAFGHLGPP---------GKRGLSGVPGIKGPRGDPG 789 Query: 1006 AQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKG--------DINGSFLMSGPPGL 1057 G GP +L L KG G GF G G G I G + G PG Sbjct: 790 CPGAEGPAGIPGFLG--LKGPKGREGHAGFPGVPGPPGHSCERGAPGIPGQPGLPGYPGS 847 Query: 1058 PGNPGPAGQKGETVVGPQGPPGAPGLPGPPGFGRPGDPGPPGPPGPPGPPAILGAAVALP 1117 PG PG GQ G+ VGP GP G GLPG P GRPG GPPG PG PGP G LP Sbjct: 848 PGAPGGKGQPGD--VGPPGPAGMKGLPGLP--GRPGAHGPPGLPGIPGPFGDDG----LP 899 Query: 1118 GPPGPPGQPGLPG 1130 GPPGP G GLPG Sbjct: 900 GPPGPKGPRGLPG 912 Score = 332 bits (850), Expect = 2e-90 Identities = 267/736 (36%), Positives = 318/736 (43%), Gaps = 148/736 (20%) Query: 525 ESGSPPPDGPPLPLPTVAPERWITPAQRE-HVGMKGQAGPKGEKGDAGEE---------- 573 E GS P GPP P + P P GM+G GP G GD G++ Sbjct: 60 EKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFPG 119 Query: 574 ---LPGPPEPSGPVGPTAGAEAEGS-----------GLGWGSDVG--------SGSGDLV 611 +PG P P GP G + GS LG G +G S ++ Sbjct: 120 LDGIPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGALGPGGPLGHPGEKGEKGNSVFIL 179 Query: 612 GSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQP--GVD 669 G+ + ++G G PG PGLPG G G G PG PG GP G+PG PG +G P GV Sbjct: 180 GAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVK 239 Query: 670 GATGLPGMKGEKGARGP------------NGSVGEKGDPGNRGLPGPPGKKGQAGPPGVM 717 G G PG G++G+ GP G G KG PG GLPGPPG+KG++G G Sbjct: 240 GQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESG-IGAK 298 Query: 718 GPPGPPGPPGPPG-PGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKG 776 G G PG PGP G PG GF + G L+ +P L GL G KGD G +G Sbjct: 299 GEKGIPGFPGPRGDPGSYGSPGFPGLK--GELGLVGDPGL------FGLIGPKGDPGNRG 350 Query: 777 ERGMDGASIV------GPPGPRGPPGHIKVLSNSLINITHGFMN--FSDIPELVGPPGPD 828 G G + GPPG G PG + G + ++GPPGP Sbjct: 351 HPGPPGVLVTPPLPLKGPPGDPGFPGRYGETGDVGPPGPPGLLGRPGEACAGMIGPPGPQ 410 Query: 829 GLPGLPGFPG-------PRGPKGDTGLPGFPGLKGEQGEKGEPGAIL----TEDIPLERL 877 G PGLPG PG P G G PG PGL G G +G PG+ + + + + Sbjct: 411 GFPGLPGLPGEAGIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGI 470 Query: 878 MGKKGEPGMHG-------------APGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKG 924 GK G PG G PGPMGP GPPG G G G G PG G KG G Sbjct: 471 KGKVGPPGGRGPKGEKGNEGLCACEPGPMGPPGPPGLPGRQGSKGDLGLPGWLGTKGDPG 530 Query: 925 DPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHG 984 PG +GPPGLPG G GPPG KG + V+ H PG P HG Sbjct: 531 PPGA--EGPPGLPGKHGASGPPGNK-GAKGDMVVSRVKGHKGERGPDGPPGFPGQPGSHG 587 Query: 985 VKGEKGSWGLPGSKGE--------KGDQGAQGP--------------PGPPLDLAYLRHF 1022 G G G PG G+ KG G GP PGPP + + Sbjct: 588 RDGHAGEKGDPGPPGDHEDATPGGKGFPGPLGPPGKAGPVGPPGLGFPGPPGERGH---- 643 Query: 1023 LNNLKGENGDKGFKGEKGEKGDI----------NGSFLMSGPPGLPGNPGPAGQKG-ETV 1071 + G G +G G KG+KGD +G GPPG G PGP G G Sbjct: 644 -PGVPGHPGVRGPDGLKGQKGDTISCNVTYPGRHGPPGFDGPPGPKGFPGPQGAPGLSGS 702 Query: 1072 VGPQGPPGAPG---LPGPPGF-GRPGDPG--------PPGPPGPPGPPAILGAAVALPGP 1119 G +G PG PG +PGPPGF G GDPG P GPPGPPG P + G +PG Sbjct: 703 DGHKGRPGTPGTAEIPGPPGFRGDMGDPGFGGEKGSSPVGPPGPPGSPGVNGQK-GIPGD 761 Query: 1120 P-----GPPGQPGLPG 1130 P GPPG+ GL G Sbjct: 762 PAFGHLGPPGKRGLSG 777 Score = 296 bits (757), Expect = 1e-79 Identities = 228/592 (38%), Positives = 271/592 (45%), Gaps = 109/592 (18%) Query: 479 SGVPTD-GLAPLTATMAPERAVTSGPGDEEDLAAATTEEPLITAGGEESGSPPPDGPPLP 537 SG+P D GL + P PGDE ++A + + G+P GPP Sbjct: 941 SGLPGDRGLRGAKGAIGP-------PGDEGEMAIIS-----------QKGTPGEPGPPGD 982 Query: 538 --LPTVAPERWITPAQREHVGMKGQAGPKG-EKGDAGEE-LPGPPEPSGPVGPTAGAEAE 593 P ++ TP + G G+ GP G +G+ GE+ PGPP P GP G T Sbjct: 983 DGFPGERGDKG-TPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGST------ 1035 Query: 594 GSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSP-GEDG 652 G G L G + G PG PGPPG GI G G G P S G G Sbjct: 1036 ------GLRGFIGFPGLPGDQ----GEPGSPGPPGFSGIDGARGPKGNKGDPASHFGPPG 1085 Query: 653 PAGEPGPPGPEGQPGVDGATGLPGMKGEKGARG---PNGSVGEKGDPGNRGLPG---PPG 706 P GEPG PG G G G GLPG++G +G+ G P GS G G PG+ G+PG PG Sbjct: 1086 PKGEPGSPGCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSSGPPGCPGDHGMPGLRGQPG 1145 Query: 707 KKGQAGPPGVMGPPGPPGPPGPPGPGCTMGL----GFEDTEGSGSTQLLNEPKLSRPTAA 762 + G GP G+ G PG PGPPG GP + GL G + +G+ L++ P Sbjct: 1146 EMGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGI 1205 Query: 763 IGLKGEKGDRG-----PKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSD 817 GLKGE+GD G P G RG G GPPG GPPG + +I Sbjct: 1206 PGLKGERGDPGSPGISPPGPRGKKGPP--GPPGSSGPPGPAGATGRAPKDIPD-----PG 1258 Query: 818 IPELVGPPGPDG---LPGLPGFPGP----RGPKGDTGLPGFPGLKGEQGEKGEPGAILTE 870 P GPPGPDG PG PG PG RG GD GLPG PG G G G G Sbjct: 1259 PPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPPGPPGPPGPPGYKG----- 1313 Query: 871 DIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGV-- 928 GK G+ G G PGP GP G PG GE GLPG PGR G GL G +G+PG Sbjct: 1314 ---FPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPA 1370 Query: 929 -IMQGP--PGLPGPPGPPGPPGAV--INIKGAIFPIPVRPHCKMPVDTAHPGSPELITFH 983 + P PGLPG PG GP GA+ ++G P P CK G P L Sbjct: 1371 DVDDCPRIPGLPGAPGMRGPEGAMGLPGMRG-----PSGPGCK--------GEPGLDGRR 1417 Query: 984 GVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGF 1035 GV G GS G PG KG+ G+ G G PGPP + G+ G KGF Sbjct: 1418 GVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPI-----------GDPGPKGF 1458 Score = 291 bits (744), Expect = 4e-78 Identities = 195/501 (38%), Positives = 230/501 (45%), Gaps = 107/501 (21%) Query: 649 GEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKK 708 G GP G PGP GP G G G GL G KG +G RGP G+ G+KGD G G+PG P Sbjct: 62 GSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGPTGVPGFP--- 118 Query: 709 GQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGE 768 G G+ G PGPPGP G PG + G Sbjct: 119 ---GLDGIPGHPGPPGPRGKPG----------------------------------MSGH 141 Query: 769 KGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPD 828 G RG G G GA +GP GP G PG NS+ + + + G G Sbjct: 142 NGSRGDPGFPGGRGA--LGPGGPLGHPGEKGEKGNSVFIL-------GAVKGIQGDRGDP 192 Query: 829 GLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHG 888 GLPGLPG G GP G TG PG PGL G G+ G PG + ++ MG GE G G Sbjct: 193 GLPGLPGSWGAGGPAGPTGYPGEPGLVGPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQG 252 Query: 889 APGPMGPKGPPG---HKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGP 945 +PGP PP +KGE G+ G PG GL G G KG+ G+ +G G+PG PGP G Sbjct: 253 SPGPTLLVEPPDFCLYKGEKGIKGIPGMVGLPGPPGRKGESGIGAKGEKGIPGFPGPRGD 312 Query: 946 PGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQG 1005 PG+ PG P L G+ G+ G +GL G KG+ G++G Sbjct: 313 PGSY----------------------GSPGFPGLKGELGLVGDPGLFGLIGPKGDPGNRG 350 Query: 1006 AQGPPG----PPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNP 1061 GPPG PPL L KG GD GF G GE GD+ GPPG PG Sbjct: 351 HPGPPGVLVTPPLPL----------KGPPGDPGFPGRYGETGDV-------GPPGPPGLL 393 Query: 1062 GPAGQKGETVVGPQGPPGAPGLPGPPG-FGRPGDP-GPPGPPGPPGPPAILGAAVALPGP 1119 G G+ ++GP GP G PGLPG PG G PG P PG PG PG P G Sbjct: 394 GRPGEACAGMIGPPGPQGFPGLPGLPGEAGIPGRPDSAPGKPGKPGSP----------GL 443 Query: 1120 PGPPGQPGLPGSRNLVTAFSN 1140 PG PG GLPGS + + N Sbjct: 444 PGAPGLQGLPGSSVIYCSVGN 464 Score = 258 bits (659), Expect = 3e-68 Identities = 183/478 (38%), Positives = 217/478 (45%), Gaps = 90/478 (18%) Query: 690 VGEKGDPGNRGLPGPPGKKGQAGPPGVM------------GPPGPPGPPGPPGPGCTMGL 737 V EKG G G PGP G G G PG + GPPG G G GP T Sbjct: 58 VPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAGDKGDKGP--TGVP 115 Query: 738 GFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGH 797 GF +G + P P G+ G G RG G G GA +GP GP G PG Sbjct: 116 GFPGLDG-----IPGHPGPPGPRGKPGMSGHNGSRGDPGFPGGRGA--LGPGGPLGHPGE 168 Query: 798 IKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGE 857 NS+ + + + G G GLPGLPG G GP G TG PG PGL G Sbjct: 169 KGEKGNSVFIL-------GAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGEPGLVGP 221 Query: 858 QGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPG---HKGEFGLPGRPGRP 914 G+ G PG + ++ MG GE G G+PGP PP +KGE G+ G PG Sbjct: 222 PGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIKGIPGMV 281 Query: 915 GLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHP 974 GL G G KG+ G+ +G G+PG PGP G PG+ P Sbjct: 282 GLPGPPGRKGESGIGAKGEKGIPGFPGPRGDPGSY----------------------GSP 319 Query: 975 GSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPG----PPLDLAYLRHFLNNLKGEN 1030 G P L G+ G+ G +GL G KG+ G++G GPPG PPL LKG Sbjct: 320 GFPGLKGELGLVGDPGLFGLIGPKGDPGNRGHPGPPGVLVTPPLP----------LKGPP 369 Query: 1031 GDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPGF- 1089 GD GF G GE GD+ GPPG PG G G+ ++GP GP G PGLPG PG Sbjct: 370 GDPGFPGRYGETGDV-------GPPGPPGLLGRPGEACAGMIGPPGPQGFPGLPGLPGEA 422 Query: 1090 ---GR----PGDPGPPGPPGPPGPPAILG--------AAVALPGPPGPPGQPGLPGSR 1132 GR PG PG PG PG PG P + G +V PGP G G+ G PG R Sbjct: 423 GIPGRPDSAPGKPGKPGSPGLPGAPGLQGLPGSSVIYCSVGNPGPQGIKGKVGPPGGR 480 Score = 239 bits (609), Expect = 2e-62 Identities = 204/577 (35%), Positives = 237/577 (41%), Gaps = 106/577 (18%) Query: 423 PGEVEASGVAPGELDLSMSAQSLGEEATVGPSSEDSLTTAAAATEVSLSTFEDEEASGVP 482 PGE SG+ PG+ L G + +GP ++ E+++ + G P Sbjct: 935 PGEKGMSGL-PGDRGLR------GAKGAIGPPGDEG--------EMAIIS-----QKGTP 974 Query: 483 TDGLAPLTATMAPERAVTSGPGDEEDLAAATTEEPLITAGGE--ESGSPPPDGPPLPLPT 540 + P ER PG + P GE E G P P GPP P + Sbjct: 975 GEPGPPGDDGFPGERGDKGTPGMQGRRGEPGRYGPPGFHRGEPGEKGQPGPPGPPGPPGS 1034 Query: 541 VAPERWI-------------TPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSGPVGPT 587 +I +P G+ G GPKG KGD GPP P G G Sbjct: 1035 TGLRGFIGFPGLPGDQGEPGSPGPPGFSGIDGARGPKGNKGDPASHF-GPPGPKGEPGSP 1093 Query: 588 A-----GAEAEGSGLGWGSDVGS-GSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVF 641 GA E G GS G GS GPPG PG G+PG+ G+PG Sbjct: 1094 GCPGHFGASGEQGLPGIQGPRGSPGRPGPPGSS----GPPGCPGDHGMPGLRGQPGE--- 1146 Query: 642 MGPPGSPGEDGPAGEPGPPG---PEGQPGVDGATGLPGMKGEKGARG-----PNGSVGEK 693 MG PG G G G PGPPG P G PG++G GL G KG KGA G P G VG Sbjct: 1147 MGDPGPRGLQGDPGIPGPPGIKGPSGSPGLNGLHGLKGQKGTKGASGLHDVGPPGPVGIP 1206 Query: 694 GDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNE 753 G G RG PG PG GP G GPPGPPG GPPGP G +D G Sbjct: 1207 GLKGERGDPGSPGIS-PPGPRGKKGPPGPPGSSGPPGPAGATGRAPKDIPDPGPPGDQGP 1265 Query: 754 PKLSRPTAAIGLKGEKGD----RGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINIT 809 P P A G G G RG G+ G+ G GPPGP GPPG+ + Sbjct: 1266 PGPDGPRGAPGPPGLPGSVDLLRGEPGDCGLPGPP--GPPGPPGPPGYKGFPGCDGKDGQ 1323 Query: 810 HGFMNFSDIPELVGPPGPDGLPGLPG---FPGPRGPKGDTGLPG---------------- 850 G + F GP GP G PG PG PGP G KG TGLPG Sbjct: 1324 KGPVGFP------GPQGPHGFPGPPGEKGLPGPPGRKGPTGLPGPRGEPGPPADVDDCPR 1377 Query: 851 FPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGR 910 PGL G G +G GA+ + G KGEPG+ G +G G+PG Sbjct: 1378 IPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEPGL------------DGRRGVDGVPGS 1425 Query: 911 PGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPG 947 PG PG G G G P G PG PGP G PGP G Sbjct: 1426 PGPPGRKGDTGEDGYP-----GGPGPPGPIGDPGPKG 1457 Score = 144 bits (364), Expect = 4e-34 Identities = 103/258 (39%), Positives = 118/258 (45%), Gaps = 57/258 (22%) Query: 556 GMKGQAGPKGEKGDAGEELP--GPPEPSGPVGPTAGAEAEGS-GLGWGSDVGSGS-GD-- 609 G G GP G G A +++P GPP GP GP A G GL D+ G GD Sbjct: 1236 GSSGPPGPAGATGRAPKDIPDPGPPGDQGPPGPDGPRGAPGPPGLPGSVDLLRGEPGDCG 1295 Query: 610 LVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVD 669 L G GPPGPPGPPG G PG G D GP G PG GP G PGPPG +G PG Sbjct: 1296 LPGPP----GPPGPPGPPGYKGFPGCDGKDGQKGPVGFPGPQGPHGFPGPPGEKGLPGPP 1351 Query: 670 GA---TGLPGMKGEKGA-------------------RGPNGSVGE-----------KGDP 696 G TGLPG +GE G RGP G++G KG+P Sbjct: 1352 GRKGPTGLPGPRGEPGPPADVDDCPRIPGLPGAPGMRGPEGAMGLPGMRGPSGPGCKGEP 1411 Query: 697 G---NRGL------PGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGS 747 G RG+ PGPPG+KG G G G PGPPGP G PGP GF G Sbjct: 1412 GLDGRRGVDGVPGSPGPPGRKGDTGEDGYPGGPGPPGPIGDPGP-----KGFGPGYLGGF 1466 Query: 748 TQLLNEPKLSRPTAAIGL 765 +L+ PT +G+ Sbjct: 1467 LLVLHSQTDQEPTCPLGM 1484 Score = 120 bits (301), Expect = 9e-27 Identities = 89/241 (36%), Positives = 108/241 (44%), Gaps = 42/241 (17%) Query: 931 QGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKG 990 +G G PGPPGP GP G + GA PI + M D PG+ G KG+KG Sbjct: 61 KGSRGPPGPPGPQGPIGPL----GAPGPIGLSGEKGMRGDRGPPGAA------GDKGDKG 110 Query: 991 SWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFL 1050 G+PG G G G GPPGP +G+ G G G +G+ G G Sbjct: 111 PTGVPGFPGLDGIPGHPGPPGP--------------RGKPGMSGHNGSRGDPGFPGGRGA 156 Query: 1051 MSGPPGLPGNPGPAGQKGETVV------GPQGPPGAPGLPGPPGF----------GRPGD 1094 + GP G G+PG G+KG +V G QG G PGLPG PG G PG+ Sbjct: 157 L-GPGGPLGHPGEKGEKGNSVFILGAVKGIQGDRGDPGLPGLPGSWGAGGPAGPTGYPGE 215 Query: 1095 PGPPGPPGPPGPPAILG-AAVALPGPPGPPGQPGLPGSRNLVTAFSNMDDMLQKAHLVIE 1153 PG GPPG PG P + G V + G G PG+ G GS D L K I+ Sbjct: 216 PGLVGPPGQPGRPGLKGNPGVGVKGQMGDPGEVGQQGSPGPTLLVEPPDFCLYKGEKGIK 275 Query: 1154 G 1154 G Sbjct: 276 G 276 Score = 48.1 bits (113), Expect = 6e-05 Identities = 35/97 (36%), Positives = 41/97 (42%), Gaps = 29/97 (29%) Query: 1062 GPAGQKGETVVGPQGPPGAPGLPGPPG-------FGRP------------GDPGPP---- 1098 GP G + +V G+ G PGPPG G P GD GPP Sbjct: 45 GPCGGRDCSVCHCVPEKGSRGPPGPPGPQGPIGPLGAPGPIGLSGEKGMRGDRGPPGAAG 104 Query: 1099 -----GPPGPPGPPAILGAAVALPGPPGPPGQPGLPG 1130 GP G PG P + G PGPPGP G+PG+ G Sbjct: 105 DKGDKGPTGVPGFPGLDGIP-GHPGPPGPRGKPGMSG 140 >gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] Length = 1073 Score = 358 bits (919), Expect = 2e-98 Identities = 290/818 (35%), Positives = 349/818 (42%), Gaps = 155/818 (18%) Query: 373 GEAEASSVPTGGPTLSMSTENPEEGVTPGPDNEERLAATAAGEAEALASMPGEVEASGVA 432 GEA + P T S+ T +P GP E+ G+ +PGE G Sbjct: 322 GEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEK-------GDP----GLPGEPGLQG-R 369 Query: 433 PGELDLSMSAQSLGEEATVGPSSEDSLTTAAAATEVSLSTFEDEEASGVPTDGLAPLTAT 492 PGEL G + GP A A + + G P + Sbjct: 370 PGEL---------GPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSG--PPGSV 418 Query: 493 MAPERAVTSGPGDEEDLAAATTEE--PLITAGGEESGSPPPDGPPLPLPTVAPERWITPA 550 AP T G E A EE P + G+P GPP P +P Sbjct: 419 GAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPG 478 Query: 551 QREHVGMKGQAGPKG------EKGDAGEELPGPPEPSGPVGPTA-----------GAEAE 593 +G KG G G +GD G + GPP PSGP G G + Sbjct: 479 LPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGP 538 Query: 594 GSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPG------IPGKPGTDVFMGPPGS 647 G S + G +L+ + PPGPPG PGLPG +PGKPG + G G Sbjct: 539 AGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGRE---GTEGK 595 Query: 648 PGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGK 707 GE GP G PGPPG G G G G G G+KG +G G G G PGN G PG G Sbjct: 596 KGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGI 655 Query: 708 KGQAGPPGVMGPPGPPGPPGPPGPGCTMGL-GFEDTEG-SGSTQLLNEP-KLSRPTAAIG 764 G AGPPG+ G PG GPPGP GP G+ G E EG G EP K P G Sbjct: 656 AGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEP----G 711 Query: 765 LKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGP 824 L G +G RGP G +G G S G PGPRG G +G Sbjct: 712 LPGPEGARGPPGFKGHTGDS--GAPGPRGESG------------------------AMGL 745 Query: 825 PGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEP 884 PG +GLPG G GP GP+G G G PG G G GEPG T P ++ G KGE Sbjct: 746 PGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGT---PGQK--GSKGEN 800 Query: 885 GMHGAPGPMGPKGPPGHKGEFGLPGR---PGRPGLNGLKGTKGDPGVIM-QGPPGLPGPP 940 G G PG +GP+GPPG GE G+PG+ PG+PG G KG +GDPG+ +GPPG G P Sbjct: 801 GSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQP 860 Query: 941 GPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGE 1000 G PG PG H G L+ G+ GE G G PG G+ Sbjct: 861 GDPGIPG-------------------------HKGHTGLMGPQGLPGENGPVGPPGPPGQ 895 Query: 1001 KGDQGAQGPP--------------GPPLD--LAYLRH-----FLNNLKGENGDKGFKGEK 1039 G G +G G L+ LAYL ++ + +G G G G+ Sbjct: 896 PGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKD 955 Query: 1040 GEKGDINGSFLMSGPPGLPGNPGPAGQKGET-VVGPQGPPGAPGLPGPPGFGRPGDPGPP 1098 G G +GP G PG PG G +G + +GP+G GA G PG PG G G+ GPP Sbjct: 956 GLPG-------RAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPP 1008 Query: 1099 GPPGPPGPPAILGAAVALPGPPGPPGQ------PGLPG 1130 G PG PG P A LPG PGP G+ PGLPG Sbjct: 1009 GIPGQPGEPGY--AKDGLPGIPGPQGETGPAGHPGLPG 1044 Score = 357 bits (915), Expect = 6e-98 Identities = 270/728 (37%), Positives = 320/728 (43%), Gaps = 190/728 (26%) Query: 525 ESGSPPPDGPP-LPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPE---- 579 E G P GPP LP T TP H M G+ GPKGEKGD G LPG P Sbjct: 320 EKGEAGPAGPPGLPGTTSL----FTP----HPRMPGEQGPKGEKGDPG--LPGEPGLQGR 369 Query: 580 -----PSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPG 634 P GP GP EG+ G+ G+ VG+ GP GPPG G PG+ G Sbjct: 370 PGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAP----GPSGPPGSVGAPGLRG 425 Query: 635 KPGTDV------FMGPPGSPGEDGPAGEPGPPG--------PEGQPGVDGATGLPGMKGE 680 PG D G GSPG GP G+PG PG +G+PG+ G+ GLPG G Sbjct: 426 TPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGT 485 Query: 681 KGARG-----------------------PNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVM 717 KG RG P+G G+KG PG+RGLPG PG +G AG G+ Sbjct: 486 KGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLS 545 Query: 718 G------------------PPGPPGPPGPPGPGCTMGL----GFEDTEG----SGSTQLL 751 PPGPPG PG PG G+ G E TEG +G L Sbjct: 546 SLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLP 605 Query: 752 NEPKLSRPTAAIGLKGEKGDRGPKGERGMDGA-SIVGPPGPRGPPGHIKVLSNSLINITH 810 P ++ P + G +G G+ G KG++G G +GPPG GPPG Sbjct: 606 GPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPG-------------- 651 Query: 811 GFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTE 870 + G GP G+ G PG GP GP+G +GLPG PG +G++G G+PG Sbjct: 652 -------ADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGP---- 700 Query: 871 DIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIM 930 P E GK GEPG+ G G GP G GH G+ G PG G G GL G +G PG Sbjct: 701 --PGEP--GKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDG 756 Query: 931 Q-GPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEK 989 GP G GP GP GPPG PGSP G G+K Sbjct: 757 DTGPTGPQGPQGPRGPPGK----------------------NGSPGSPGEPGPSGTPGQK 794 Query: 990 GSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSF 1049 GS G GS G G G +GPPG P + + G+ G+ GFKGE+G+ G I G Sbjct: 795 GSKGENGSPGLPGFLGPRGPPGEPGEKGVPGK--EGVPGKPGEPGFKGERGDPG-IKGDK 851 Query: 1050 LMSGPPGLPGNPGPAGQKGET-VVGPQGPPGAPGLPGPPGF-GRPGDPG----------- 1096 G G PG+PG G KG T ++GPQG PG G GPPG G+PG PG Sbjct: 852 GPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETL 911 Query: 1097 -----------------------PP-------GPPGPPGPPAILGAAVALPGPPGPPGQP 1126 PP G PGPPGPP G LPG GP G+P Sbjct: 912 RRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDG----LPGRAGPMGEP 967 Query: 1127 GLPGSRNL 1134 G PG L Sbjct: 968 GRPGQGGL 975 Score = 355 bits (911), Expect = 2e-97 Identities = 277/750 (36%), Positives = 325/750 (43%), Gaps = 155/750 (20%) Query: 500 TSGPGDEEDLAAATTEEPLITAGG-----EESGSPPPDGPPLPLPTVAPERWITPAQREH 554 T GP D+ A A+ TA G E G DG P P R Sbjct: 221 TQGPADQRADARASCILAAKTAPGLKQLNGEPGERGEDGLPGK-----------PGLRGE 269 Query: 555 VGMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGS-GL-GWGSDVG-------S 605 +G +G AG GEKG+AG LPG P G G +G GL G D G + Sbjct: 270 IGEQGLAGRPGEKGEAG--LPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPA 327 Query: 606 GSGDLVGSEQL------LRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGP 659 G L G+ L + G GP G G PG+PG+PG G PG G GP G PG Sbjct: 328 GPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPG---LQGRPGELGPQGPTGPPGA 384 Query: 660 PGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGP 719 G EG G GA G PG G GA GP+G G G PG RG PG G++G+ G G G Sbjct: 385 KGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGS 444 Query: 720 PGPPGPPGPPG-PGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGER 778 PGP GP G PG PG G G L P L P G +G G G G R Sbjct: 445 PGPVGPRGDPGAPGLP---GPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSR 501 Query: 779 GMDGASIVGPPGPRGPPGHIKVLSNSLINITHG------------FMNFSDIPELVG--- 823 G G + GPPGP GPPG + + G ++ DI L Sbjct: 502 GDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVC 561 Query: 824 ---PPGPDGLPGLPGF---------------PGPRGPKGDTGLPGFPGLKGEQGEKGEPG 865 PPGP GLPGLPGF G +G G GLPG PG+ G QG +GE G Sbjct: 562 NDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERG 621 Query: 866 AILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGD 925 A + +G+KG+ G G PG MGP G PG G G+ G G PG+ G G +G Sbjct: 622 A--------DGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGP 673 Query: 926 PGVIMQGPPGLP------------GPPGPPGPPG-----AVINIKGAIFPIPVRPHCKMP 968 PG QGP GLP G PGPPG PG + +GA P + H Sbjct: 674 PG--PQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGH---- 727 Query: 969 VDTAHPGSPELITFHGVKGEKGSWGLPGSK---------GEKGDQGAQGPPGPPLDLAYL 1019 T G+P G +GE G+ GLPG + G G QG QGP GPP Sbjct: 728 --TGDSGAP------GPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPP-----G 774 Query: 1020 RHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGET-VVGPQGPP 1078 ++ GE G G G+KG KG+ +G PGLPG GP G GE G G Sbjct: 775 KNGSPGSPGEPGPSGTPGQKGSKGE-------NGSPGLPGFLGPRGPPGEPGEKGVPGKE 827 Query: 1079 GAPGLPGPPGF-------GRPGDPGPPGPPGPPGPPAILG--------AAVALP------ 1117 G PG PG PGF G GD GPPG G PG P I G LP Sbjct: 828 GVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPV 887 Query: 1118 GPPGPPGQPGLPGSRNLVTAFSNMDDMLQK 1147 GPPGPPGQPG PG R + + ++Q+ Sbjct: 888 GPPGPPGQPGFPGLRGESPSMETLRRLIQE 917 Score = 293 bits (750), Expect = 8e-79 Identities = 228/664 (34%), Positives = 273/664 (41%), Gaps = 182/664 (27%) Query: 479 SGVPTDGLAPLTATMAPERAVTSGPGDEEDLAAATTEEPLITAGGEESGSPPPDGPPLP- 537 SG P D +P + + P GP + L++ + + + PP P LP Sbjct: 515 SGPPGDKGSPGSRGL-PGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCNDCPPGPPGLPG 573 Query: 538 LPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEE-LPGPPEPSGPVGPTAGAEAEGSG 596 LP ++ + G G+ G +G+KG+AG LPGPP +GP G A+G Sbjct: 574 LPGFKGDKGVP-------GKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGE- 625 Query: 597 LGWGSDVGS----------------GSGDLVGS--------EQLLRGPPGPPGPPGLPGI 632 +G D G G+ + G+ GPPGP GP GLPGI Sbjct: 626 VGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGI 685 Query: 633 PGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGE 692 PG+ G + G PG PGE G AGEPG PGPE G G G G G+ GA GP G G Sbjct: 686 PGEEGKEGRDGKPGPPGEPGKAGEPGLPGPE---GARGPPGFKGHTGDSGAPGPRGESGA 742 Query: 693 KGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPG-PGCTMGLGFEDTEGSGSTQLL 751 G PG GLPG G G GP G GP GPPG G PG PG Sbjct: 743 MGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPG------------------- 783 Query: 752 NEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHG 811 EP G G G +G KGE G G + G GPRGPPG Sbjct: 784 -EP---------GPSGTPGQKGSKGENGSPG--LPGFLGPRGPPGE-------------- 817 Query: 812 FMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTED 871 P G PG +G+PG PG PG +G +GD PG G KG G KG+P Sbjct: 818 -------PGEKGVPGKEGVPGKPGEPGFKGERGD---PGIKGDKGPPGGKGQP------- 860 Query: 872 IPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGD------ 925 G G PG G G MGP+G PG G G PG PG+PG GL+G Sbjct: 861 -------GDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRR 913 Query: 926 ---------------------PGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPH 964 P M+ G PGPPGPPG G + G P+ Sbjct: 914 LIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDG----LPGRAGPM----- 964 Query: 965 CKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLN 1024 PG P G+ G G G G KG++GA+G PG P Sbjct: 965 -------GEPGRP---------GQGGLEGPSGPIGPKGERGAKGDPGAP---------GV 999 Query: 1025 NLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLP 1084 L+GE G G G+ GE G GLPG PGP G+ GP G PG PG P Sbjct: 1000 GLRGEMGPPGIPGQPGEPG--------YAKDGLPGIPGPQGE-----TGPAGHPGLPGPP 1046 Query: 1085 GPPG 1088 GPPG Sbjct: 1047 GPPG 1050 Score = 272 bits (696), Expect = 1e-72 Identities = 194/529 (36%), Positives = 234/529 (44%), Gaps = 90/529 (17%) Query: 658 GPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDP------------GNRGLPGPP 705 G GP Q A+ + K G + NG GE+G+ G +GL G P Sbjct: 220 GTQGPADQRADARASCILAAKTAPGLKQLNGEPGERGEDGLPGKPGLRGEIGEQGLAGRP 279 Query: 706 GKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGL-GFEDTEG-SGSTQLLNEPKLSRPTAAI 763 G+KG+AG PG G PG G G G +GL G + G G P L T+ Sbjct: 280 GEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLF 339 Query: 764 ----------GLKGEKGDRGPKGERGMDG-ASIVGPPGPRGPPGHIKVLSNSLINITHGF 812 G KGEKGD G GE G+ G +GP GP GPPG G Sbjct: 340 TPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPG------------AKGQ 387 Query: 813 MNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDI 872 P G P G PG G PGP GP G G PG G G+ GE+GE GA E Sbjct: 388 EGAHGAPGAAGNP---GAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGS 444 Query: 873 PLERLMGKKGEPGMHGAPGPMGP--------KGPPGHKGEFGLPGRPGRPGLNGLKGTKG 924 P +G +G+PG G PGP G +G PG G G G G PG+ G G++G Sbjct: 445 P--GPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGSPGSRG 502 Query: 925 DPGVIMQGPPGLPGPPGPPGPPGA--------------VINIKGAIFPIPVRPHCKMPVD 970 DPG+ + GPPG GPPG G PG+ + + P + K + Sbjct: 503 DPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGDINLLAKDVCN 562 Query: 971 TAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGEN 1030 PG P L G KG+KG G PG +G +G +G GPPG P + +G Sbjct: 563 DCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPG-----IAGPQGSQ 617 Query: 1031 GDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPGF- 1089 G++G GE G+KGD G PG+PG GP G GP G G G GPPG Sbjct: 618 GERGADGEVGQKGD-------QGHPGVPGFMGPPGNP-----GPPGADGIAGAAGPPGIQ 665 Query: 1090 GRPGDPGPPGPPGPPGPPAILG-----AAVALPGPPGPP---GQPGLPG 1130 G PG GPPGP GP G P I G PGPPG P G+PGLPG Sbjct: 666 GSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPG 714 Score = 193 bits (491), Expect = 8e-49 Identities = 148/391 (37%), Positives = 168/391 (42%), Gaps = 65/391 (16%) Query: 527 GSPPPDGPPLPL-PTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSGPVG 585 GSP +GPP P P+ P P + G G+ GP GE G AGE PG P P G G Sbjct: 666 GSPGKEGPPGPQGPSGLPG---IPGEEGKEGRDGKPGPPGEPGKAGE--PGLPGPEGARG 720 Query: 586 PTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLL--------------RGPPGPPGPPGLPG 631 P G G SG+ L G E L +GP GPPG G PG Sbjct: 721 PPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPG 780 Query: 632 IPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVG 691 PG+PG G GS GE+G G PG GP G PG G G+PG +G G G G G Sbjct: 781 SPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKG 840 Query: 692 EKGDPGNRGLPGPPGKKGQAGPPGV---------MGPPG------PPGPPGPPGPGCTMG 736 E+GDPG +G GPPG KGQ G PG+ MGP G P GPPGPPG G Sbjct: 841 ERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPG 900 Query: 737 LGFEDTEGSGSTQLLNEP---------------------KLSR----PTAAIGLKGEKGD 771 L E +L+ E K S+ P G G G Sbjct: 901 LRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGR 960 Query: 772 RGPKGERGMDG-ASIVGPPGPRGPPGHIKVLSNSLINIT--HGFMNFSDIPELVGPPG-- 826 GP GE G G + GP GP GP G + G M IP G PG Sbjct: 961 AGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYA 1020 Query: 827 PDGLPGLPGFPGPRGPKGDTGLPGFPGLKGE 857 DGLPG+PG G GP G GLPG PG G+ Sbjct: 1021 KDGLPGIPGPQGETGPAGHPGLPGPPGPPGQ 1051 Score = 129 bits (324), Expect = 2e-29 Identities = 96/260 (36%), Positives = 117/260 (45%), Gaps = 57/260 (21%) Query: 525 ESGSPP------PDGPP-------LPLPTVAPERWITPA---QREHVGMKGQAGPKGEKG 568 E+GSP P GPP +P P + P +R G+KG GP G KG Sbjct: 799 ENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKG 858 Query: 569 DAGEE----------LPGP---PEPSGPVGPTAGAEAEG-SGLGWGSDVGSGSGDLVGSE 614 G+ L GP P +GPVGP G GL S L+ E Sbjct: 859 QPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEE 918 Query: 615 ---------------------QLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGP 653 + +G PGPPGPPG G+PG+ G MG PG PG+ G Sbjct: 919 LGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGP---MGEPGRPGQGGL 975 Query: 654 AGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPG--NRGLPGPPGKKGQA 711 G GP GP+G+ G G G PG+ G +G GP G G+ G+PG GLPG PG +G+ Sbjct: 976 EGPSGPIGPKGERGAKGDPGAPGV-GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGET 1034 Query: 712 GPPGVMGPPGPPGPPGPPGP 731 GP G G PGPPGPPG P Sbjct: 1035 GPAGHPGLPGPPGPPGQCDP 1054 Score = 71.2 bits (173), Expect = 6e-12 Identities = 48/120 (40%), Positives = 53/120 (44%), Gaps = 17/120 (14%) Query: 575 PGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPG 634 PGPP P G G G G G G L G GP GP G G G PG Sbjct: 946 PGPPGPPGKDG------LPGRAGPMGEPGRPGQGGLEGPS----GPIGPKGERGAKGDPG 995 Query: 635 KPGTDVF--MGPPGSPGEDGPAGE-----PGPPGPEGQPGVDGATGLPGMKGEKGARGPN 687 PG + MGPPG PG+ G G PG PGP+G+ G G GLPG G G P+ Sbjct: 996 APGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPS 1055 Score = 46.2 bits (108), Expect = 2e-04 Identities = 43/141 (30%), Positives = 53/141 (37%), Gaps = 21/141 (14%) Query: 1029 ENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPG--------- 1079 EN D+G +G G N S L S P G + +G QGP Sbjct: 179 ENVDQGAQGACGRG---NTSVLPSSVAPQCSMPKGTGHEFSAALGTQGPADQRADARASC 235 Query: 1080 ------APGLPGPPGFGRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRN 1133 APGL G PG+ G G PG PG +G L G PG G+ GLPG+ Sbjct: 236 ILAAKTAPGLKQLNG--EPGERGEDGLPGKPGLRGEIGEQ-GLAGRPGEKGEAGLPGAPG 292 Query: 1134 LVTAFSNMDDMLQKAHLVIEG 1154 D +K L + G Sbjct: 293 FPGVRGEKGDQGEKGELGLPG 313 >gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] Length = 1626 Score = 357 bits (915), Expect = 6e-98 Identities = 264/709 (37%), Positives = 311/709 (43%), Gaps = 162/709 (22%) Query: 525 ESGSPPPDGPP-LPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPE---- 579 E G P GPP LP T TP H M G+ GPKGEKGD G LPG P Sbjct: 838 EKGEAGPAGPPGLPGTTSL----FTP----HPRMPGEQGPKGEKGDPG--LPGEPGLQGR 887 Query: 580 -----PSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPG 634 P GP GP EG+ G+ G+ VG+ GP GPPG G PG+ G Sbjct: 888 PGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAP----GPSGPPGSVGAPGLRG 943 Query: 635 KPGTDV------FMGPPGSPGEDGPAGEPGPPG--------PEGQPGVDGATGLPGMKGE 680 PG D G GSPG GP G+PG PG +G+PG+ G+ GLPG G Sbjct: 944 TPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGT 1003 Query: 681 KGARGP-----NGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTM 735 K A G N ++G + G+RG PG PG G G PG+ G GPPGP GPPG Sbjct: 1004 KAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGI-GVAGPPGPSGPPG----- 1057 Query: 736 GLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVG-------- 787 D GS L P P G G G+RGP G+ G+ G Sbjct: 1058 -----DKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKD 1112 Query: 788 -----PPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVG---------PPGPDGLPGL 833 PPGP G PG GF +P G GP GLPG Sbjct: 1113 VCNDCPPGPPGLPG------------LPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGP 1160 Query: 834 PGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIP----LERLMGKKGEPGMHGA 889 PG GP+G +G+ G G G KG+QG G PG + P + + G G PG+ G+ Sbjct: 1161 PGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGS 1220 Query: 890 PGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAV 949 PG GP GP G G G+PG G+ G +G G G+PG G PGLPGP G GPPG Sbjct: 1221 PGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPG--KAGEPGLPGPEGARGPPG-- 1276 Query: 950 INIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKG---------E 1000 KG T G+P G +GE G+ GLPG +G Sbjct: 1277 --FKG---------------HTGDSGAP------GPRGESGAMGLPGQEGLPGKDGDTGP 1313 Query: 1001 KGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGN 1060 G QG QGP GPP ++ GE G G G+KG KG+ +G PGLPG Sbjct: 1314 TGPQGPQGPRGPPG-----KNGSPGSPGEPGPSGTPGQKGSKGE-------NGSPGLPGF 1361 Query: 1061 PGPAGQKGET-VVGPQGPPGAPGLPGPPGF-------GRPGDPGPPGPPGPPGPPAILG- 1111 GP G GE G G G PG PG PGF G GD GPPG G PG P I G Sbjct: 1362 LGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPGH 1421 Query: 1112 -------AAVALPG------PPGPPGQPGLPGSRNLVTAFSNMDDMLQK 1147 LPG PPGPPGQPG PG R + + ++Q+ Sbjct: 1422 KGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQE 1470 Score = 354 bits (908), Expect = 4e-97 Identities = 262/699 (37%), Positives = 308/699 (44%), Gaps = 175/699 (25%) Query: 529 PPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEE-LPGPPEPSGPVGPT 587 PPP PP PT E+ + + AG KGE G AG LPGP G +GP Sbjct: 451 PPPPPPPQRPPTPGSEQI---GFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPV 507 Query: 588 AGAEAEGSGLGWGSDVGSGS-GDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPG 646 +G DVG G G E+ G PGPPG G G+ G+PG +G PG Sbjct: 508 GAPGPKGEK----GDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGE---LGEPG 560 Query: 647 SPGE------DGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRG 700 PGE GP G PGPPG G PG+ G G G +GEKG RG +G G+ GD G +G Sbjct: 561 LPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQG 620 Query: 701 LPGPPGKKGQAGPPGVMGPPGPPGPP-------------GPPGPGCTMGLGFEDTEG-SG 746 PGP G G G G +GP GPPG P G PGP G + G G Sbjct: 621 RPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGP-----RGHQGAPGPPG 675 Query: 747 STQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLI 806 + + P GL+G+KGD GP G G+ G + GPPGP G P Sbjct: 676 ARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLG--LQGPPGPPGVP----------- 722 Query: 807 NITHGFMNFSDIPELVGPPGPDGLPGLP---GFPGPRGPKGDTGLPGF---------PGL 854 GPPGP G PGLP GFPG GP G TG PG PG Sbjct: 723 ----------------GPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGT 766 Query: 855 KGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRP 914 KGE GE+GE G G+PG+ G G G G PG KGE GLPG PG P Sbjct: 767 KGEPGERGEDGL--------------PGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFP 812 Query: 915 GLNGLKGTKGDPGVI-------MQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKM 967 G+ G KG +G+ G + +G G GP GPPG PG ++F PH +M Sbjct: 813 GVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTT-----SLF----TPHPRM 863 Query: 968 PVDTAHPGSPELITFHGVKGEKGSWGLPGS---KGEKGDQGAQGPPGPPLDLAYLRHFLN 1024 P + G KGEKG GLPG +G G+ G QGP GPP A + + Sbjct: 864 PGE------------QGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPP--GAKGQEGAH 909 Query: 1025 NLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGET----------VVGP 1074 G G+ G G G G +G G PGL G PG G++GE VGP Sbjct: 910 GAPGAAGNPGAPGHVGAPGP-SGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGP 968 Query: 1075 QGPPGAPGLPGPPGFGRPGDPGPPGPPGPPGP---------------------------- 1106 +G PGAPGLPGPPG G+ G+PG G PG PGP Sbjct: 969 RGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRG 1028 Query: 1107 -PAILGA----------AVALPGPPGPPGQPGLPGSRNL 1134 P I G+ PGP GPPG G PGSR L Sbjct: 1029 APGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGL 1067 Score = 352 bits (903), Expect = 1e-96 Identities = 247/622 (39%), Positives = 291/622 (46%), Gaps = 119/622 (19%) Query: 556 GMKGQAGPKGEKGDAGEE-LPGPPEPSGPVGPTA-----GAEAEGSGLGWGSDVGSGSGD 609 G G +GP G+KG G LPG P P GP G G G S + G + Sbjct: 1048 GPPGPSGPPGDKGSPGSRGLPGFPGPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDIN 1107 Query: 610 LVGSEQLLRGPPGPPGPPGLPG------IPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPE 663 L+ + PPGPPG PGLPG +PGKPG + G G GE GP G PGPPG Sbjct: 1108 LLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGRE---GTEGKKGEAGPPGLPGPPGIA 1164 Query: 664 GQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPP 723 G G G G G G+KG +G G G G PGN G PG G G AGPPG+ G PG Sbjct: 1165 GPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKE 1224 Query: 724 GPPGPPGPGCTMGL-GFEDTEG-SGSTQLLNEP-KLSRPTAAIGLKGEKGDRGPKGERGM 780 GPPGP GP G+ G E EG G EP K P GL G +G RGP G +G Sbjct: 1225 GPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKAGEP----GLPGPEGARGPPGFKGH 1280 Query: 781 DGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPR 840 G S G PGPRG G +G PG +GLPG G GP Sbjct: 1281 TGDS--GAPGPRGESG------------------------AMGLPGQEGLPGKDGDTGPT 1314 Query: 841 GPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPG 900 GP+G G G PG G G GEPG T P ++ G KGE G G PG +GP+GPPG Sbjct: 1315 GPQGPQGPRGPPGKNGSPGSPGEPGPSGT---PGQK--GSKGENGSPGLPGFLGPRGPPG 1369 Query: 901 HKGEFGLPGR---PGRPGLNGLKGTKGDPGVIM-QGPPGLPGPPGPPGPPGAVINIKGAI 956 GE G+PG+ PG+PG G KG +GDPG+ +GPPG G PG PG PG Sbjct: 1370 EPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKGQPGDPGIPG--------- 1420 Query: 957 FPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPP------ 1010 H G L+ G+ GE G G PG G+ G G +G Sbjct: 1421 ----------------HKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETL 1464 Query: 1011 --------GPPLD--LAYLRH-----FLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPP 1055 G L+ LAYL ++ + +G G G G+ G G +GP Sbjct: 1465 RRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPG-------RAGPM 1517 Query: 1056 GLPGNPGPAGQKGET-VVGPQGPPGAPGLPGPPGFGRPGDPGPPGPPGPPGPPAILGAAV 1114 G PG PG G +G + +GP+G GA G PG PG G G+ GPPG PG PG P A Sbjct: 1518 GEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGY--AKD 1575 Query: 1115 ALPGPPGPPGQ------PGLPG 1130 LPG PGP G+ PGLPG Sbjct: 1576 GLPGIPGPQGETGPAGHPGLPG 1597 Score = 343 bits (879), Expect = 9e-94 Identities = 262/709 (36%), Positives = 302/709 (42%), Gaps = 135/709 (19%) Query: 525 ESGSPPPDGPP-LPLPTVAPERWITPAQREHVGMKGQAGPKGEKG-DAGEELPGPPEPSG 582 E G P GPP LP P P R P + G KG G KGE+G D PG G Sbjct: 564 EVGMRGPQGPPGLPGP---PGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQG 620 Query: 583 PVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFM 642 GP+ A +G G G V ++ L+G G PGP G G PG PG + Sbjct: 621 RPGPSGVAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPI 680 Query: 643 GPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLP 702 GP G G G G G G G PG+ G GL G G G GP G G G PG G P Sbjct: 681 GPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGPPGVPGPPGPGGSPGLPGEIGFP 740 Query: 703 GPPGKKGQAGPPGVMGPPGPPGPPGPPG-------------PGCTMGLGFEDTEGSGSTQ 749 G PG G GPPG GP GPPGPPG G PG +G + G + Sbjct: 741 GKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGLRGEIGEQGLAGRPGEK 800 Query: 750 LLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDG----ASIVGPPGPRGPPGHIKVLSNSL 805 E L G++GEKGD+G KGE G+ G G GP GPPG L Sbjct: 801 --GEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPG--------L 850 Query: 806 INITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGD---TGLPGFPGLKGEQGEKG 862 T F +P GP G G PGLPG PG +G G+ G G PG KG++G G Sbjct: 851 PGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHG 910 Query: 863 EPGAILTEDIP-------------------------LERLMGKKGEPGMHGAPGPMGPKG 897 PGA P + G+KG G G+PGP+GP+G Sbjct: 911 APGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRG 970 Query: 898 PPG--------HKGEFGLPGRPGRPGLNGLKGTKGDPGVIM---------------QGPP 934 PG KG+ G PG G PGL G GTK G + +G P Sbjct: 971 DPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAP 1030 Query: 935 GLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGL 994 G+PG PG G PG I + G P P P P D PGS L F G +G G G Sbjct: 1031 GIPGSPGSRGDPG--IGVAGP--PGPSGP----PGDKGSPGSRGLPGFPGPQGPAGRDGA 1082 Query: 995 PGSKGEKGDQGAQG---------------------PPGPPLDLAYLRHFLNNLKGENGDK 1033 PG+ GE+G G G PPGPP L L G GDK Sbjct: 1083 PGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPP--------GLPGLPGFKGDK 1134 Query: 1034 GFKGEKGEKGDINGSFLMSGPPGLPGNP---GPAGQKGETVV-------GPQGPPGAPGL 1083 G G+ G +G G +GPPGLPG P GP G +GE G QG PG PG Sbjct: 1135 GVPGKPGREG-TEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGF 1193 Query: 1084 PGPPGFGRPGDPGPPGPPGPPGPPAILGA--AVALPGPPGPPGQPGLPG 1130 GPP G PG PG G G GPP I G+ PGP GP G PG+PG Sbjct: 1194 MGPP--GNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPG 1240 Score = 292 bits (747), Expect = 2e-78 Identities = 224/649 (34%), Positives = 266/649 (40%), Gaps = 181/649 (27%) Query: 494 APERAVTSGPGDEEDLAAATTEEPLITAGGEESGSPPPDGPPLP-LPTVAPERWITPAQR 552 AP GP + L++ + + + PP P LP LP ++ + Sbjct: 1082 APGNPGERGPPGKPGLSSLLSPGDINLLAKDVCNDCPPGPPGLPGLPGFKGDKGVP---- 1137 Query: 553 EHVGMKGQAGPKGEKGDAGEE-LPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGS------ 605 G G+ G +G+KG+AG LPGPP +GP G A+G +G D G Sbjct: 1138 ---GKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGE-VGQKGDQGHPGVPGF 1193 Query: 606 ----------GSGDLVGS--------EQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGS 647 G+ + G+ GPPGP GP GLPGIPG+ G + G PG Sbjct: 1194 MGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGP 1253 Query: 648 PGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGK 707 PGE G AGEPG PGPE G G G G G+ GA GP G G G PG GLPG G Sbjct: 1254 PGEPGKAGEPGLPGPE---GARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGD 1310 Query: 708 KGQAGPPGVMGPPGPPGPPGPPG-PGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLK 766 G GP G GP GPPG G PG PG EP G Sbjct: 1311 TGPTGPQGPQGPRGPPGKNGSPGSPG--------------------EP---------GPS 1341 Query: 767 GEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPG 826 G G +G KGE G G + G GPRGPPG P G PG Sbjct: 1342 GTPGQKGSKGENGSPG--LPGFLGPRGPPGE---------------------PGEKGVPG 1378 Query: 827 PDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGM 886 +G+PG PG PG +G +GD PG G KG G KG+P G G PG Sbjct: 1379 KEGVPGKPGEPGFKGERGD---PGIKGDKGPPGGKGQP--------------GDPGIPGH 1421 Query: 887 HGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGD--------------------- 925 G G MGP+G PG G G PG PG+PG GL+G Sbjct: 1422 KGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLA 1481 Query: 926 ------PGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPEL 979 P M+ G PGPPGPPG G + G P+ PG P Sbjct: 1482 YLLAQMPPAYMKSSQGRPGPPGPPGKDG----LPGRAGPM------------GEPGRP-- 1523 Query: 980 ITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEK 1039 G+ G G G G KG++GA+G PG P L+GE G G G+ Sbjct: 1524 -------GQGGLEGPSGPIGPKGERGAKGDPGAP---------GVGLRGEMGPPGIPGQP 1567 Query: 1040 GEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPG 1088 GE G GLPG PGP G+ GP G PG PG PGPPG Sbjct: 1568 GEPG--------YAKDGLPGIPGPQGE-----TGPAGHPGLPGPPGPPG 1603 Score = 291 bits (746), Expect = 2e-78 Identities = 217/576 (37%), Positives = 252/576 (43%), Gaps = 160/576 (27%) Query: 645 PGSPGEDGPAGEPGPPGP--------------------------EGQPGVDGATGLPGMK 678 P P + EP PP P +G+ GV G GLPG K Sbjct: 439 PSGPCQVTVVTEPPPPPPPQRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPK 498 Query: 679 GEKGARGPNGS----------------VGEKGDPGNRGLPGPPGK---KGQAGPP----- 714 G+ GA GP G+ GEKG+ G+ GLPGPPG+ KG G P Sbjct: 499 GDIGAIGPVGAPGPKGEKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPGELGE 558 Query: 715 -------GVMGPPGPPGPPGPPG----PGCTMGLGFEDTEG-SGSTQLLNEPKLSRPTAA 762 G+ GP GPPG PGPPG PG G + T G G L P T Sbjct: 559 PGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQ 618 Query: 763 IGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELV 822 G G G GP+GE+G VGP GP G PG + G P Sbjct: 619 QGRPGPSGVAGPQGEKG-----DVGPAGPPGVPGSVVQ--------QEGLKGEQGAP--- 662 Query: 823 GPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKG 882 GP G G PG PG GP GP+G G PG GL+G++G+ G PG + L+G +G Sbjct: 663 GPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPG--------IPGLLGLQG 714 Query: 883 EPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGP 942 PG G PGP GP G PG GE G PG+PG PG GPPG GP GP Sbjct: 715 PPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPG--------------PTGPPGKDGPNGP 760 Query: 943 PGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKG 1002 PGPPG KG P + G P G++GE G GL G GEKG Sbjct: 761 PGPPGT----KGE------------PGERGEDGLPGK---PGLRGEIGEQGLAGRPGEKG 801 Query: 1003 DQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGE------KGEKGDINGSFLMSGPPG 1056 + G G PG P ++GE GD+G KGE KG++G+ G +GPPG Sbjct: 802 EAGLPGAPGFP-----------GVRGEKGDQGEKGELGLPGLKGDRGE-KGEAGPAGPPG 849 Query: 1057 LPG-----NPGPAGQKGETVVGPQGPPGAPGLPGPPGF-GRPGDPGPPGPPGPPGPPAIL 1110 LPG P P GE GP+G G PGLPG PG GRPG+ GP GP GPPG Sbjct: 850 LPGTTSLFTPHPR-MPGEQ--GPKGEKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQE 906 Query: 1111 GA--------------AVALPGPPGPPGQPGLPGSR 1132 GA V PGP GPPG G PG R Sbjct: 907 GAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLR 942 Score = 215 bits (547), Expect = 3e-55 Identities = 164/467 (35%), Positives = 202/467 (43%), Gaps = 111/467 (23%) Query: 716 VMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPK 775 V PP PP P PP PG +E G + +N + +G+ G G GPK Sbjct: 448 VTEPPPPPPPQRPPTPG---------SEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPK 498 Query: 776 GERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPG 835 G+ G G VG PGP+G G + + G L GPPG DG G+ G Sbjct: 499 GDIGAIGP--VGAPGPKGEKGDVGIGP-----FGQGEKGEKGSLGLPGPPGRDGSKGMRG 551 Query: 836 FPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGP 895 PG G + GLPG G++G QG G PG G+ G PG+ G G Sbjct: 552 EPGELG---EPGLPGEVGMRGPQGPPGLPGP-----------PGRVGAPGLQGE---RGE 594 Query: 896 KGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGA 955 KG G KGE GL G PG+PG G +G G GV GP G G GP GPPG Sbjct: 595 KGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVA--GPQGEKGDVGPAGPPGV------- 645 Query: 956 IFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLD 1015 PGS ++ G+KGE+G+ G G +G G GA+GP GP Sbjct: 646 ------------------PGS--VVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGP--- 682 Query: 1016 LAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGET-VVGP 1074 +G +G G +G +G+KGD+ GPPG+PG G G G V GP Sbjct: 683 -----------EGRDGPPGLQGLRGKKGDM-------GPPGIPGLLGLQGPPGPPGVPGP 724 Query: 1075 QGPPGAPGLPGPPGF-GRPGDPGPPGPPG------PPGPPAILG---------------- 1111 GP G+PGLPG GF G+PG PGP GPPG PPGPP G Sbjct: 725 PGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPGERGEDGLPGKPGL 784 Query: 1112 ----AAVALPGPPGPPGQPGLPGSRNLVTAFSNMDDMLQKAHLVIEG 1154 L G PG G+ GLPG+ D +K L + G Sbjct: 785 RGEIGEQGLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPG 831 Score = 193 bits (491), Expect = 8e-49 Identities = 148/391 (37%), Positives = 168/391 (42%), Gaps = 65/391 (16%) Query: 527 GSPPPDGPPLPL-PTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSGPVG 585 GSP +GPP P P+ P P + G G+ GP GE G AGE PG P P G G Sbjct: 1219 GSPGKEGPPGPQGPSGLPG---IPGEEGKEGRDGKPGPPGEPGKAGE--PGLPGPEGARG 1273 Query: 586 PTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLL--------------RGPPGPPGPPGLPG 631 P G G SG+ L G E L +GP GPPG G PG Sbjct: 1274 PPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPG 1333 Query: 632 IPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVG 691 PG+PG G GS GE+G G PG GP G PG G G+PG +G G G G G Sbjct: 1334 SPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKG 1393 Query: 692 EKGDPGNRGLPGPPGKKGQAGPPGV---------MGPPG------PPGPPGPPGPGCTMG 736 E+GDPG +G GPPG KGQ G PG+ MGP G P GPPGPPG G Sbjct: 1394 ERGDPGIKGDKGPPGGKGQPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPG 1453 Query: 737 LGFEDTEGSGSTQLLNEP---------------------KLSR----PTAAIGLKGEKGD 771 L E +L+ E K S+ P G G G Sbjct: 1454 LRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGR 1513 Query: 772 RGPKGERGMDG-ASIVGPPGPRGPPGHIKVLSNSLINIT--HGFMNFSDIPELVGPPG-- 826 GP GE G G + GP GP GP G + G M IP G PG Sbjct: 1514 AGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMGPPGIPGQPGEPGYA 1573 Query: 827 PDGLPGLPGFPGPRGPKGDTGLPGFPGLKGE 857 DGLPG+PG G GP G GLPG PG G+ Sbjct: 1574 KDGLPGIPGPQGETGPAGHPGLPGPPGPPGQ 1604 Score = 129 bits (324), Expect = 2e-29 Identities = 96/260 (36%), Positives = 117/260 (45%), Gaps = 57/260 (21%) Query: 525 ESGSPP------PDGPP-------LPLPTVAPERWITPA---QREHVGMKGQAGPKGEKG 568 E+GSP P GPP +P P + P +R G+KG GP G KG Sbjct: 1352 ENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGGKG 1411 Query: 569 DAGEE----------LPGP---PEPSGPVGPTAGAEAEG-SGLGWGSDVGSGSGDLVGSE 614 G+ L GP P +GPVGP G GL S L+ E Sbjct: 1412 QPGDPGIPGHKGHTGLMGPQGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEE 1471 Query: 615 ---------------------QLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGP 653 + +G PGPPGPPG G+PG+ G MG PG PG+ G Sbjct: 1472 LGKQLETRLAYLLAQMPPAYMKSSQGRPGPPGPPGKDGLPGRAGP---MGEPGRPGQGGL 1528 Query: 654 AGEPGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPG--NRGLPGPPGKKGQA 711 G GP GP+G+ G G G PG+ G +G GP G G+ G+PG GLPG PG +G+ Sbjct: 1529 EGPSGPIGPKGERGAKGDPGAPGV-GLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGET 1587 Query: 712 GPPGVMGPPGPPGPPGPPGP 731 GP G G PGPPGPPG P Sbjct: 1588 GPAGHPGLPGPPGPPGQCDP 1607 Score = 71.2 bits (173), Expect = 6e-12 Identities = 48/120 (40%), Positives = 53/120 (44%), Gaps = 17/120 (14%) Query: 575 PGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPG 634 PGPP P G G G G G G L G GP GP G G G PG Sbjct: 1499 PGPPGPPGKDG------LPGRAGPMGEPGRPGQGGLEGPS----GPIGPKGERGAKGDPG 1548 Query: 635 KPGTDVF--MGPPGSPGEDGPAGE-----PGPPGPEGQPGVDGATGLPGMKGEKGARGPN 687 PG + MGPPG PG+ G G PG PGP+G+ G G GLPG G G P+ Sbjct: 1549 APGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPPGPPGQCDPS 1608 >gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] Length = 1860 Score = 352 bits (903), Expect = 1e-96 Identities = 367/1247 (29%), Positives = 483/1247 (38%), Gaps = 254/1247 (20%) Query: 26 VTQTRGATETASQGHLDLTQLIGVPL--------PSSVSFVTGYGGFPAYSFGPGANVGR 77 + T+GA E +D+ Q +G+ P + F +G+ F A + Sbjct: 36 LASTQGAPED-----VDILQRLGLSWTKAGSPAPPGVIPFQSGF------IFTQRARLQA 84 Query: 78 PARTLIPSTFFRDFAISVVVKPSSTRGGVLFAITDAFQKVIYLGLRLSGVEDGHQRIILY 137 P T+IP+ + A+ + + LFA+ +K + LGL+ Sbjct: 85 PTGTVIPAALGTELALVLSLCSHRVNHAFLFAVRSQKRK-LQLGLQFL------------ 131 Query: 138 YTEPGSHV----SQEAAAFSVPVMTHRWNRFAMIVQGEEVTLLVNCEEHS---RIPFQRS 190 PG V S+ + AF + + RW+ A+ ++G VTL+ C + +PF R Sbjct: 132 ---PGKTVVHLGSRRSVAFDLDMHDGRWHHLALELRGRTVTLVTACGQRRVPVLLPFHRD 188 Query: 191 SQALAFESSAGIFMGNAGATGLERFTGSLQQLTVHPDPRTPEELCDPEESSASGETSGLQ 250 A + G ++ F G+L Q +++P + C G+ Q Sbjct: 189 P---ALDPGGSFLFGKMNPHAVQ-FEGALCQFSIYPVTQVAHNYCTHLRKQC-GQADTYQ 243 Query: 251 EADGVAEILEAVTYTQASPKEAKVEPIN-TPPTPSSPFEDMELSGEPVPEGTLETTNMSI 309 G ++ A + N T TP+ L P GT+ + Sbjct: 244 SPLGPLFSQDSGRPFTFQSDLALLGLENLTTATPALG----SLPAGRGPRGTVAPATPTK 299 Query: 310 IQHSSPKQGSGEILNDTLEGVHSVDGDPITDSGSGAGAFLDIAEEKNLAATAAGLAEVPI 369 Q +SP T H G P A A + L A+ G P Sbjct: 300 PQRTSP----------TNPHQHMAVGGPAQTPLLPAKLSASNALDPMLPASVGGSTRTPR 349 Query: 370 STAGEAE----ASSVPTGGPT---------LSMSTENPEEGVTPGPDNEERLAATAAGEA 416 A + A+ +P PT + + + +P + P + L T Sbjct: 350 PAAAQPSQKITATKIPKSLPTKPSAPSTSIVPIKSPHPTQKTAPSSFTKSALP-TQKQVP 408 Query: 417 EALASMPGEVEASGVAPGELDLSMSAQSLGEEATVGPSSEDSLTT--AAAATEVSLSTFE 474 +P V P + + M + P++ S A TE +++ Sbjct: 409 PTSRPVPARVSRPAEKPIQRNPGMPRPPPPSTRPLPPTTSSSKKPIPTLARTEAKITSHA 468 Query: 475 DEEASGVPTDGLAPLTATMAPERAVTSGPGDEEDLAAATTEEPLITAGGEESGSPPPDGP 534 + AS + P ++ A T G + +T P S P P Sbjct: 469 SKPASARTSTHKPPPFTALSSSPAPTPG-------STRSTRPPATMVPPTSGTSTPRTAP 521 Query: 535 PLPLPTVAPERWITPAQREHVGMKGQAGPKGEK--------GDAGEELP----------G 576 +P P AP P E +AGPK G A ++P Sbjct: 522 AVPTPGSAPTGSKKPIGSE---ASKKAGPKSSPRKPVPLRPGKAARDVPLSDLTTRPSPR 578 Query: 577 PPEPSGPVGPT---AGAEAEGSGLGWGSDVGSGSGDLVGSEQ--LLRGPPGP------PG 625 P+PS P A A+ S S G L GS LL GPPGP PG Sbjct: 579 QPQPSQQTTPALVLAPAQFLSSSPRPTSS-GYSIFHLAGSTPFPLLMGPPGPKGDCGLPG 637 Query: 626 PPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGP------EGQPGV------DGATG 673 PPGLPG+PG PG GP G PG P G PG PGP +G PG+ DGA G Sbjct: 638 PPGLPGLPGIPGA---RGPRGPPG---PYGNPGLPGPPGAKGQKGDPGLSPGKAHDGAKG 691 Query: 674 LPGMKGEKGARGPNGSVGEK------GDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPG 727 G+ G G GP G G K G PG +G PGP G G G PG G PGP G PG Sbjct: 692 DMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPG 751 Query: 728 PPGPGCTMGL-GFEDTEGS-GSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASI 785 P G +GL G GS G L P G G G+RGP G G G Sbjct: 752 PKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGE-- 809 Query: 786 VGPPGPRGPPGHIKVLSNSLINITH-------GFMNFSDIPELVGPPGPDGLPGLPGFPG 838 +G PGP G PG I L L I + G M P L G G G+PG+ G PG Sbjct: 810 LGLPGPPGVPGLIGDL-GVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPG 868 Query: 839 PRGPKGDTGLPGFPGLKGEQGEKGE---------PGAILTEDIPLE-------RLMGKKG 882 +G KG GLPGFPG +G+ G G+ PG E P + G KG Sbjct: 869 FQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKG 928 Query: 883 EPGMHGAPGPM---------GPKGPPGHKGEFGLPGR---PGRPGLNGLKGTKGDPG--- 927 +PG G PGP GP GPPG G G PGR PGRPGL+G+KG GDPG Sbjct: 929 KPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEPGDPGRPG 988 Query: 928 -------------------VIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMP 968 V +G G+ GPPG PGP G++ H MP Sbjct: 989 PVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSM-------------GHPGMP 1035 Query: 969 VDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKG 1028 PG P G +G GS G PG +G KG +G +GP GP G Sbjct: 1036 GGMGTPGEP------GPQGPPGSRGPPGMRGAKGRRGPRGPDGP--------------AG 1075 Query: 1029 ENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPG 1088 E G +G KG G + G PG PG G AG++G +G +G PG PG GPPG Sbjct: 1076 EQGSRGLKGPPGPQ----------GRPGRPGQQGVAGERGH--LGSRGFPGIPGPSGPPG 1123 Query: 1089 F-GRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNL 1134 G PG+PGP GP GP GPP +G GPPG G+PGLPG + Sbjct: 1124 TKGLPGEPGPQGPQGPIGPPGEMGP----KGPPGAVGEPGLPGEAGM 1166 Score = 338 bits (868), Expect = 2e-92 Identities = 273/775 (35%), Positives = 336/775 (43%), Gaps = 188/775 (24%) Query: 527 GSPPPDGPPLP--------------LPTVAPERWI--TPAQREHVGMKGQAGPKGEKGDA 570 G P P G P P LP ER + P +R +GM G G GE+G Sbjct: 742 GLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRGKMGMPGFPGVFGERGPP 801 Query: 571 GEE-------LPGPPEPSGPVGPTA--GAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPP 621 G + LPGPP G +G G G +GS + ++ +G P Sbjct: 802 GLDGNPGELGLPGPPGVPGLIGDLGVLGPIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVP 861 Query: 622 GPPGPPGLPG------IPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPG---VDGAT 672 G G PG G +PG PG GP G G+ G G PGPPGPEG PG G Sbjct: 862 GVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDN 921 Query: 673 GLPGMKGEKGARG---PNGSVGEKGD------PGNRGLPGPPGKKGQAGPPGVMGPPGPP 723 G GMKG+ GARG P G +G +GD PG GL G PG+KG G PG+ G G P Sbjct: 922 GPEGMKGKPGARGLPGPRGQLGPEGDEGPMGPPGAPGLEGQPGRKGFPGRPGLDGVKGEP 981 Query: 724 GPPGPPGPGCTMG-LGFEDTEG-------SGSTQLLNEPKLSRPTAAI------------ 763 G PG PGP G +GF G G ++ P + P ++ Sbjct: 982 GDPGRPGPVGEQGFMGFIGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTP 1041 Query: 764 ------------------GLKGEKGDRGPKGERGMDGA-SIVGPPGPRGPPGHIKVLSNS 804 G KG +G RGP G G G+ + GPPGP+G PG Sbjct: 1042 GEPGPQGPPGSRGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGR---PGQQ 1098 Query: 805 LINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEP 864 + G + P + GP GP G GLPG PGP+GP+G G PG G KG G GEP Sbjct: 1099 GVAGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEP 1158 Query: 865 G----AILTEDI-PL-----ERLMGKKGEPGMHGAPGPMGP------KGPPGHKGEFGLP 908 G A + D+ PL + L+G++GEPG+ G GPMGP +G PG GE G Sbjct: 1159 GLPGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEK 1218 Query: 909 GR---------PGRPGLNGLKGTKGDPG-------------------VIMQGPPGLPGPP 940 G+ PG PG+ G++G +G G + G PG PGPP Sbjct: 1219 GQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPP 1278 Query: 941 GPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGE 1000 G PGP G+ +G++ P P G P L + G KG G G PG KGE Sbjct: 1279 GTPGPKGS----RGSLGPTGA------PGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGE 1328 Query: 1001 KGDQG----AQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPG 1056 KG+QG A+GPPGPP D + +GE GD G+ G++G +G + G G PG Sbjct: 1329 KGEQGEDGKAEGPPGPPGDRGPVGD--RGDRGEPGDPGYPGQEGVQG-LRGKPGQQGQPG 1385 Query: 1057 LPGN---PGPAGQKG-ETVVGPQGPPGAP---------GLPGPPGF-------------- 1089 PG PGP G KG E G QG GAP GLPGP G Sbjct: 1386 HPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDG 1445 Query: 1090 --------------GRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPG 1130 G GDPGP GP G G P + G A GPPG G+ GLPG Sbjct: 1446 LPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGA-QGPPGFKGESGLPG 1499 Score = 336 bits (862), Expect = 8e-92 Identities = 249/644 (38%), Positives = 296/644 (45%), Gaps = 94/644 (14%) Query: 555 VGMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSE 614 +G+ G+ G GEKGD G + GPP GP G + G G+G + G Sbjct: 999 IGLVGEPGIVGEKGDRG--MMGPPGVPGPKG-SMGHPGMPGGMGTPGEPGP--------- 1046 Query: 615 QLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGL 674 +GPPG GPPG+ G G+ G GP G GE G G GPPGP+G+PG G G+ Sbjct: 1047 ---QGPPGSRGPPGMRGAKGRRGP---RGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGV 1100 Query: 675 PGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGP---PGVMGPPGPPGPPGPPG- 730 G +G G+RG G G G PG +GLPG PG +G GP PG MGP GPPG G PG Sbjct: 1101 AGERGHLGSRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGL 1160 Query: 731 ---PGCTMGLGFEDTEGS-GSTQLLNEPKL---SRPTAAIGLKGEKGDRGPKGERGMDGA 783 G LG T G G EP L S P GLKG++GD GP GE G G Sbjct: 1161 PGEAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQ 1220 Query: 784 SIV----GPPGP------RGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGL 833 + GPPGP RGP G G + +G PG G PG Sbjct: 1221 EGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQLGEMGVPGDPGPPGT 1280 Query: 834 PGFPGPRGPKGDTGLPGF------PGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGM- 886 PG G RG G TG PG PGL G G KG G + E+ G++GE G Sbjct: 1281 PGPKGSRGSLGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEK--GEQGEDGKA 1338 Query: 887 HGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPP 946 G PGP G +GP G +G+ G PG PG PG G++G +G PG QG PG PGP G PGP Sbjct: 1339 EGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPG--QQGQPGHPGPRGWPGPK 1396 Query: 947 GAVINIKGAIFPIPVRPHCKMPVDTAH------PGSPELITFHGVKGEKGSWGLPGSKGE 1000 G+ KGA P + P PG ++ G++G G GLPG G+ Sbjct: 1397 GS----KGAEGPKGKQGKAGAPGRRGVQGLQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQ 1452 Query: 1001 KGDQGAQGPPGPPLDLAYLRHFLN----NLKGENGDKGFKGEKGEKGDIN--GSFLMSGP 1054 G QG QG G P + N L G G GFKGE G G + G G Sbjct: 1453 AGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGAQGPPGFKGESGLPGQLGPPGKRGTEGR 1512 Query: 1055 PGLPGNPGPAGQKGET-------------VVGPQGPPGAPGLPG------PPGF-GRPGD 1094 GLPGN G G KG+ + GP+GPPG G G PPG G+ G Sbjct: 1513 TGLPGNQGEPGSKGQPGDSGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGI 1572 Query: 1095 PGPPG---PPGPPGPPAILGAA-----VALPGPPGPPGQPGLPG 1130 GP G P G PGP G+ GPPGP G+PG PG Sbjct: 1573 VGPLGILGPSGLPGPKGDKGSRGDWGLQGPRGPPGPRGRPGPPG 1616 Score = 329 bits (844), Expect = 1e-89 Identities = 249/698 (35%), Positives = 309/698 (44%), Gaps = 152/698 (21%) Query: 549 PAQREHVGMKGQAGPKGEKGDAG----EELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVG 604 P H G +GQ GP+G G G + LPGP GP G G GSD Sbjct: 714 PGPAGHPGEQGQPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDGE 773 Query: 605 SGSGDLVGSEQLLRGPPGPPGPPGL------PGIPGKPGTDVFMGPPGSPGEDGPAGEPG 658 G + G RG G PG PG+ PG+ G PG GPPG PG G G G Sbjct: 774 RGLPGVPGK----RGKMGMPGFPGVFGERGPPGLDGNPGELGLPGPPGVPGLIGDLGVLG 829 Query: 659 P---PGPEGQPGVDGATGLPGMKGEKGARGPNGSVGE---KGDPGNRGLPGPPGKKGQAG 712 P PGP+G G+ G+ G PG+KG+KG +G G G+ +GD G++GLPG PG +G+ G Sbjct: 830 PIGYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPG 889 Query: 713 PPGVMGPPGPPGPPGPPGP-------GCTMGLGFEDTEGSGSTQLLNEPKLSR------- 758 P G +G G G PGPPGP G G E +G + L P+ Sbjct: 890 PLGKVGDKGSIGFPGPPGPEGFPGDIGPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEG 949 Query: 759 ---PTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNF 815 P A GL+G+ G +G G G+DG + G PG G PG + GFM F Sbjct: 950 PMGPPGAPGLEGQPGRKGFPGRPGLDG--VKGEPGDPGRPGPVG---------EQGFMGF 998 Query: 816 SDI---PELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDI 872 + P +VG G G+ G PG PGP+G G G+PG G GE G +G PG+ Sbjct: 999 IGLVGEPGIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGS------ 1052 Query: 873 PLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGL---------PGRPGRPGLNGLKGTK 923 +G PGM GA G GP+GP G GE G GRPGRPG G+ G + Sbjct: 1053 --------RGPPGMRGAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGER 1104 Query: 924 GDPGVIMQGPPGLPGPPGPPG---------------------------PPGAV------- 949 G G +G PG+PGP GPPG PPGAV Sbjct: 1105 GHLG--SRGFPGIPGPSGPPGTKGLPGEPGPQGPQGPIGPPGEMGPKGPPGAVGEPGLPG 1162 Query: 950 -INIKGAIFPIPVRPHCKMPVDTAHPG--------SPELITFHGVKGEKGSWGLPGSKGE 1000 +KG + P+ + PG P+ G+KG++G G G GE Sbjct: 1163 EAGMKGDLGPLGTPGEQGLIGQRGEPGLEGDSGPMGPD-----GLKGDRGDPGPDGEHGE 1217 Query: 1001 KGDQGAQG---PPGPPLDLAYLR--HFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPP 1055 KG +G G PPGPP + +R + +GE G G KG KG +G + G + G P Sbjct: 1218 KGQEGLMGEDGPPGPP-GVTGVRGPEGKSGKQGEKGRTGAKGAKGYQGQL-GEMGVPGDP 1275 Query: 1056 GLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPGF-------GRPGDPGPPGPPGPPGPPA 1108 G PG PGP G +G +GP G PG G G PG G G GPPGP G G Sbjct: 1276 GPPGTPGPKGSRGS--LGPTGAPGRMGAQGEPGLAGYDGHKGIVGPLGPPGPKGEKGEQG 1333 Query: 1109 ILGAAVALPGPP------------GPPGQPGLPGSRNL 1134 G A PGPP G PG PG PG + Sbjct: 1334 EDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGV 1371 Score = 286 bits (732), Expect = 1e-76 Identities = 215/583 (36%), Positives = 260/583 (44%), Gaps = 54/583 (9%) Query: 525 ESGSPPPDGPPLPLPTVA-PERWITPAQREHVGMKG------QAGPKGEKGDAGEELPGP 577 E GS GPP P P + +R H+G +G +GP G KG GE PGP Sbjct: 1076 EQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGPSGPPGTKGLPGE--PGP 1133 Query: 578 PEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKPG 637 P GP+GP +G G G + G GP G PG GL G G+PG Sbjct: 1134 QGPQGPIGPPGEMGPKGPPGAVGEPGLPGEAGMKGD----LGPLGTPGEQGLIGQRGEPG 1189 Query: 638 TDVFMGPPGSPGEDGPAGEPGPPGP---EGQPGVDGATGLPGMKGEKGARGPNGSVGEKG 694 + GP G G G G+PGP G +GQ G+ G G PG G G RGP G G++G Sbjct: 1190 LEGDSGPMGPDGLKGDRGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQG 1249 Query: 695 DPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEP 754 + G G G G +GQ G GV G PGPPG PGP G ++G T G EP Sbjct: 1250 EKGRTGAKGAKGYQGQLGEMGVPGDPGPPGTPGPKGSRGSLG----PTGAPGRMGAQGEP 1305 Query: 755 KLSRPTAAIGLKGEKGDRGPKGERGMDG--ASIVGPPGPRGPPGHIKVLSNSLINITHGF 812 L+ G+ G G GPKGE+G G GPPGP G G + + G+ Sbjct: 1306 GLAGYDGHKGIVGPLGPPGPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGY 1365 Query: 813 MNFSDIPELVGPPGPDGLPGLPG---FPGPRG------PKGDTGLPGFPGLKGEQGEKGE 863 + L G PG G PG PG +PGP+G PKG G G PG +G QG +G Sbjct: 1366 PGQEGVQGLRGKPGQQGQPGHPGPRGWPGPKGSKGAEGPKGKQGKAGAPGRRGVQGLQGL 1425 Query: 864 PGAI-LTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKGT 922 PG + LE + G G PG G G G +G G G G G+ G PG+ GL G Sbjct: 1426 PGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPMGPAGKRGNPGVAGLPGA 1485 Query: 923 KGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITF 982 +G PG +G GLPG GPPG G +P + PGS Sbjct: 1486 QGPPG--FKGESGLPGQLGPPGKRGT-------------EGRTGLPGNQGEPGSKGQPGD 1530 Query: 983 HGVKGEKGSWGLPGSKGEKGD---QGAQGPPGPPLDLAYLRHFLNNLK--GENGDKGFKG 1037 G G G GL G KG GD +G QGP GPP L + L G +G G KG Sbjct: 1531 SGEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPP-GLMGKEGIVGPLGILGPSGLPGPKG 1589 Query: 1038 EKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPGA 1080 +KG +GD G GPPG G PGP G G + Q GA Sbjct: 1590 DKGSRGDW-GLQGPRGPPGPRGRPGPPGPPGGPIQLQQDDLGA 1631 Score = 281 bits (719), Expect = 3e-75 Identities = 265/839 (31%), Positives = 332/839 (39%), Gaps = 164/839 (19%) Query: 355 KNLAATAAGLAEVPISTAGEAEASSVPTGGPTLSMSTE--NPEEGVTPG-----PDNEER 407 +NL L +P AG +V PT T NP + + G P + Sbjct: 270 ENLTTATPALGSLP---AGRGPRGTVAPATPTKPQRTSPTNPHQHMAVGGPAQTPLLPAK 326 Query: 408 LAATAAGEAEALASMPGEVEASGVAPGELDLSMSAQSLGEEATVGPSSEDSLTTAAAATE 467 L+A+ A + AS+ G A + ++A + + PS+ + + Sbjct: 327 LSASNALDPMLPASVGGSTRTPRPAAAQPSQKITATKIPKSLPTKPSAPSTSIVPIKSPH 386 Query: 468 VSLSTFEDE-EASGVPTDGLAPLTATMAPERAVTSGPGDEEDLAAATTEEPLITAGGEES 526 + T S +PT P T+ P R + E+P+ G Sbjct: 387 PTQKTAPSSFTKSALPTQKQVPPTSRPVPARV------------SRPAEKPIQRNPGMPR 434 Query: 527 GSPPPDGPPLPLPTVAPERWITPAQR------EHVGMKGQAGPKGEKGDAGEELPGPPEP 580 PPP PLP T + ++ I R H A K L P P Sbjct: 435 -PPPPSTRPLPPTTSSSKKPIPTLARTEAKITSHASKPASARTSTHKPPPFTALSSSPAP 493 Query: 581 SGP-----------VGPTAGAEAEGSG--LGWGSDVGSGSGDLVGSEQLLR-GPPGPPGP 626 + V PT+G + + +GS +GSE + GP P Sbjct: 494 TPGSTRSTRPPATMVPPTSGTSTPRTAPAVPTPGSAPTGSKKPIGSEASKKAGPKSSPRK 553 Query: 627 PGLPGIPGKPGTDVFMGP---PGSPGEDGPAGEPGP-------------PGPEGQP---- 666 P +P PGK DV + SP + P+ + P P P Sbjct: 554 P-VPLRPGKAARDVPLSDLTTRPSPRQPQPSQQTTPALVLAPAQFLSSSPRPTSSGYSIF 612 Query: 667 GVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPP 726 + G+T P + G G P G G G PG GLPG PG +G GPPG G PG PGPP Sbjct: 613 HLAGSTPFPLLMGPPG---PKGDCGLPGPPGLPGLPGIPGARGPRGPPGPYGNPGLPGPP 669 Query: 727 GPPG----PGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDG 782 G G PG + G + +G + P LS G KG KG GP G G G Sbjct: 670 GAKGQKGDPGLSPGKAHDGAKGD-----MGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQG 724 Query: 783 ASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGP 842 PGP G PG G PG GLPG G PGP+G Sbjct: 725 Q-----PGPEGSPG------------------------AKGYPGRQGLPGPVGDPGPKGS 755 Query: 843 KGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPG-- 900 +G GLPG GL G GE+G PG + GK+G+ GM G PG G +GPPG Sbjct: 756 RGYIGLPGLFGLPGSDGERGLPG-----------VPGKRGKMGMPGFPGVFGERGPPGLD 804 Query: 901 -HKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAV--INIKGAIF 957 + GE GLPG PG PGL G D GV+ GP G PGP G G G+V +KG Sbjct: 805 GNPGELGLPGPPGVPGLIG------DLGVL--GPIGYPGPKGMKGLMGSVGEPGLKG--- 853 Query: 958 PIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLA 1017 D G P + G +G+KGS GLPG G +G G G G + Sbjct: 854 ------------DKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPLGKVGDKGSIG 901 Query: 1018 YLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKG-ETVVGPQG 1076 + G G +GF G+ G GD NG M G PG G PGP GQ G E GP G Sbjct: 902 F--------PGPPGPEGFPGDIGPPGD-NGPEGMKGKPGARGLPGPRGQLGPEGDEGPMG 952 Query: 1077 PPGAPGLPGPPGFGRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNLV 1135 PPGAPGL G PG R G PG PG G G P PG PGP G+ G G LV Sbjct: 953 PPGAPGLEGQPG--RKGFPGRPGLDGVKGEPGD-------PGRPGPVGEQGFMGFIGLV 1002 Score = 86.3 bits (212), Expect = 2e-16 Identities = 73/223 (32%), Positives = 86/223 (38%), Gaps = 41/223 (18%) Query: 994 LPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSG 1053 L G G KGD G GPPG P G G G +G +G G G Sbjct: 623 LMGPPGPKGDCGLPGPPGLP--------------GLPGIPGARGPRGPPGPY-------G 661 Query: 1054 PPGLPGNPGPAGQKGETVVGP----------QGPPGAPGLPGPPGFGRPGDPGPPGPPGP 1103 PGLPG PG GQKG+ + P G PG G PGPPG R G G PGP G Sbjct: 662 NPGLPGPPGAKGQKGDPGLSPGKAHDGAKGDMGLPGLSGNPGPPG--RKGHKGYPGPAGH 719 Query: 1104 PGPPAILGAAVALPGPPGPPGQPGLPGSRNLVTAFSNMDDMLQKAHLVIEGTFIYLRDST 1163 PG PGP G PG G PG + L + + ++ + G F Sbjct: 720 PGEQG-------QPGPEGSPGAKGYPGRQGLPGPVGDPGPKGSRGYIGLPGLFGLPGSDG 772 Query: 1164 EFFIRVRDGWKKLQLGELIPIPADSPPPPALSSNPHQL-LPPP 1205 E + G + P PP L NP +L LP P Sbjct: 773 ERGLPGVPGKRGKMGMPGFPGVFGERGPPGLDGNPGELGLPGP 815 >gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo sapiens] Length = 1424 Score = 350 bits (897), Expect = 7e-96 Identities = 261/690 (37%), Positives = 291/690 (42%), Gaps = 174/690 (25%) Query: 558 KGQA---GPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSE 614 KGQ G KGEKG+ G PGPP G G T EG Sbjct: 36 KGQCFCDGAKGEKGEKG--FPGPPGSPGQKGFTG---PEG-------------------- 70 Query: 615 QLLRGPPGPPGPPGLP---------GIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQ 665 L GP GP G PGLP GI G PG G PG+PG GP G G PG G Sbjct: 71 --LPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGS 128 Query: 666 PGVDGATGLPGMKGEKGARGPNGSVGEKGDP-----------GNRGLPGPPGKKGQAGPP 714 G G GLPG G G G G G+KG P G+ GLPG PG +G GPP Sbjct: 129 KGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPP 188 Query: 715 GVMGPPGPPGPP---------GPPGPGCTMGLGFEDTEGSGSTQLLNEP---------KL 756 G GP GPPGPP GP GP MG +G + L P L Sbjct: 189 GFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTL 248 Query: 757 SRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGF-MNF 815 + P LKGEKGD+G GE GPPGP G PG ++G Sbjct: 249 TGPDNRTDLKGEKGDKGAMGE--------PGPPGPSGLPGE-----------SYGSEKGA 289 Query: 816 SDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPG----AILTED 871 P L G PG DG+PG PG G +G +G GL G G+KG++G+ G PG + Sbjct: 290 PGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDT 349 Query: 872 IPLERLMGKKGEPGMHGAPGPMGPKGPPGHKG-----EFGLPGRPGRPGLNGLKGTKGDP 926 + G G PG GA GP GP GPPG G GL G PG PGL G KG +G P Sbjct: 350 YQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRP 409 Query: 927 GVIMQ---------GPPGLPGPPGPPGPPGAVINIKG--------AIFPIPVRPH----- 964 G G PGLPG PGPPGPPG ++ KG P P Sbjct: 410 GKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPK 469 Query: 965 -------CKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLA 1017 + P PG P L HGVKG G G G KG G G G PG P Sbjct: 470 GEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFP---- 525 Query: 1018 YLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGP-------------- 1063 G GD G KGEKGE G + G PGL G PG Sbjct: 526 -------GFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKG 578 Query: 1064 -AGQKGETVV----GPQGPPGAPGLP---------GPPGFGRPGD---------PGPPGP 1100 G KGE + G QGPPG PG P GPPG+G G+ PG PGP Sbjct: 579 LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGP 638 Query: 1101 PGPPGPPAILGAAVALPGPPGPPGQPGLPG 1130 PG GP L + +PGPPGPPG PG PG Sbjct: 639 PGEAGPRGELSVSTPVPGPPGPPGPPGHPG 668 Score = 349 bits (896), Expect = 9e-96 Identities = 266/703 (37%), Positives = 313/703 (44%), Gaps = 130/703 (18%) Query: 525 ESGSPPPDGPPLPLPTVAPERWITP-AQREHVGMKGQAGPKGEKGDAG-------EELPG 576 E G P P G P PE P + G+ G G KG +G +G LPG Sbjct: 50 EKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPG 109 Query: 577 PPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKP 636 P +GP G GS G G L G PG PG GL G G P Sbjct: 110 TPGNTGPYGLVGVPGCSGS---------KGEQGFPGLPGTL-GYPGIPGAAGLKGQKGAP 159 Query: 637 GTDVFM-----GPPGSPGEDGPAGEPGPPG---PEGQPGVDGATGLPGMKGEKGARGPNG 688 + + G PG PG GP G PGPPG P G PG G G PG G +G +G G Sbjct: 160 AKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMG 219 Query: 689 S--VGEKGDPGNRGLPGPPGK-----------------KGQAGPPGVMGPPGPPGPPGPP 729 +G KG+ G +GL GPPG KG+ G G MG PGPPGP G P Sbjct: 220 ERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLP 279 Query: 730 GPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGAS----I 785 G G G L +P G +G KG+RG G G DG Sbjct: 280 GESYGSEKG-----APGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGD 334 Query: 786 VGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGD 845 +GPPG RGP + T G GP GP G PG+PG PG P G Sbjct: 335 IGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGAR---GPQGPSGPPGVPGSPGSSRP-GL 390 Query: 846 TGLPGFPGLKGEQGEKGEPG--AILTEDIPLERLMGKKGEPGMHGAPGPMGP-------K 896 G PG+PGLKG +GE+G PG A+ T P G G PG+ G+PGP GP K Sbjct: 391 RGAPGWPGLKGSKGERGRPGKDAMGTPGSP-----GCAGSPGLPGSPGPPGPPGDIVFRK 445 Query: 897 GPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAI 956 GPPG + GLPG G PG+ G+ G KG+PG++ P +PGPPG PG PG + +KG Sbjct: 446 GPPG---DHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG-LHGVKG-- 499 Query: 957 FPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGD----QGAQGPPGP 1012 IP R + PGSP G G G+ G PG KGEKG+ +G G PG Sbjct: 500 --IPGRQGAAGLKGS--PGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGD 555 Query: 1013 P-LDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPG---LPGNPGPAGQKG 1068 P L R L+ + G G KG G KGE ++G GPPG PG+PGPAG G Sbjct: 556 PGLRGQPGRKGLDGIPGTPGVKGLPGPKGELA-LSGEKGDQGPPGDPGSPGSPGPAGPAG 614 Query: 1069 ETVVGPQGPPG------APGLPGPPGF--------------GRPGDPGPPGPPGPPGPPA 1108 GPQG PG PG PGPPG G PG PGPPG PGP GPP Sbjct: 615 PPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPG 674 Query: 1109 ILGA-------------------AVALPGPPGPPGQPGLPGSR 1132 I G+ + PGPPGP G G PG++ Sbjct: 675 IPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTK 717 Score = 349 bits (895), Expect = 1e-95 Identities = 270/732 (36%), Positives = 314/732 (42%), Gaps = 154/732 (21%) Query: 527 GSPPPDGPP-LPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSGPVG 585 G P P GPP P P P P G G GP GE G G PGPP P G G Sbjct: 656 GPPGPPGPPGHPGPQGPPG---IPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQG 712 Query: 586 PTAGAEAEGSGLGWGSDVGSGSGDLVGSEQ----LLRGPPGPPG---------------P 626 + G G G L G++ + G PG PG Sbjct: 713 FPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGL 772 Query: 627 PGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPG-----PEGQPGVDGATGLPGMKGEK 681 PGLPG+PG PG + GP G PG+ GP GE GPPG P G G+ G GL G +G + Sbjct: 773 PGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRR 832 Query: 682 GARGPNGS-----------------------------VGEKGDPGNRGLPGPPGKKGQAG 712 G GP G +G++G PGN G+ GPPG+ G G Sbjct: 833 GKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIG 892 Query: 713 P---PGVMGPPGPPGPPGPPG----PGCTMGLGFEDTEGS-GSTQLLNEPKLSRPTAAIG 764 PG +GPPGPPG PG PG PG G T G+ G P S + IG Sbjct: 893 MMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIG 952 Query: 765 LKGEKG------DRGPKGERGMDGA----SIVGPPGPRGPPGHIKVLSNSLINITHGFMN 814 KGE G + G KG RG+ G + G PGP GPPG L G Sbjct: 953 DKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL---------GSTG 1003 Query: 815 FSDIPELVGPPGPDGLPGLPGFPGPRGP---KGDTGLPGFPGLKGEQGEKGEPGAIL--- 868 P L G PG G G+PG G RG G G PG PG+ G QG+KGEPG Sbjct: 1004 NPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTR 1063 Query: 869 ------TEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPG------L 916 T D L MGKKGE G G PG +GP GP G G G PG PG+PG Sbjct: 1064 PGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGF 1123 Query: 917 NGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGS 976 G+KG G PG+ +GPPGLPG PG PGP G + P P + + A PG Sbjct: 1124 KGIKGLLGPPGI--RGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGP 1181 Query: 977 PELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFK 1036 G KG++G+ G PG G KG G GP GP G +GF Sbjct: 1182 RGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGP-----------------TGIEGFP 1224 Query: 1037 GEKGEKGDI-NGSFLMSGPPGL---PGNPGPAGQKGETVVG------------PQGPPGA 1080 G G G I G GPPG PG PGP G G V+G P+GPPG Sbjct: 1225 GPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGT 1284 Query: 1081 PGLPGPPG-FGRPGDPGPPGPPGPPG------------PPAILGAAVALPGPPGPPGQP- 1126 G GPPG G PG PG PGP G PG P LG+ + PGP GP G P Sbjct: 1285 AGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGS-IGPPGPIGPKGPPG 1343 Query: 1127 --GLPGSRNLVT 1136 G PG+ +++ Sbjct: 1344 VRGDPGTLKIIS 1355 Score = 345 bits (885), Expect = 2e-94 Identities = 255/714 (35%), Positives = 304/714 (42%), Gaps = 153/714 (21%) Query: 503 PGDEEDLAAATTEEPLITAGGEESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAG 562 P EED+ +P + G P P G P P+ P + G G G Sbjct: 159 PAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFF--------GFPGAMG 210 Query: 563 PKGEKGDAGEELPGPPEP------SGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQL 616 P+G KG GE + G +GP GP +G +D+ GD Sbjct: 211 PRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGD------- 263 Query: 617 LRGPPGPPGPPGLPGIPGKP-GTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLP 675 +G G PGPPG G+PG+ G++ G PG PG G G+ G PG G GV G G P Sbjct: 264 -KGAMGEPGPPGPSGLPGESYGSE--KGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFP 320 Query: 676 GMKGEKGARGPNGSVGEKG------------DPGNRGLPGPPGKKGQAGPPGVMGPPGPP 723 G+ GE G +G G +G G + G+ G PGPPG +G GP G GPPG P Sbjct: 321 GLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVP 380 Query: 724 GPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGM--- 780 G PG PG G+ GLKG KG+RG G+ M Sbjct: 381 GSPGSSRPGLRGAPGWP-----------------------GLKGSKGERGRPGKDAMGTP 417 Query: 781 ------DGASIVGPPGPRGPPGHIKVLSNSL-INITHGFMNFSDIPELVGP--------- 824 + G PGP GPPG I + G++ IP + GP Sbjct: 418 GSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCT 477 Query: 825 -----PGPDGLPGLPGFPGPR---------------GPKGDTGLPGFPGLKGEQGE---K 861 PGP GLPGLPG G + G G+TGLPGFPG G QG+ K Sbjct: 478 QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK 537 Query: 862 GEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKG 921 GE G E + E +G G+PG+ G PG G G PG G GLPG G L+G KG Sbjct: 538 GEKG----ETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKG 593 Query: 922 TKGDPGVIMQGPPGLPGPPGPPGPPG----------AVINIKGAIFPI-PVRPHCKMPVD 970 +G PG G PG PGP GP GPPG + GA P P ++ V Sbjct: 594 DQGPPG--DPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVS 651 Query: 971 TAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGP-----------PGPPLDLAYL 1019 T PG P G G +G G+PGS G+ GD G GP PGPP Sbjct: 652 TPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPP------ 705 Query: 1020 RHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPG 1079 G GD+GF G KG G G PGLPG PG G KGE V G PG Sbjct: 706 --------GPKGDQGFPGTKGSLGCPG----KMGEPGLPGKPGLPGAKGEPAVAMPGGPG 753 Query: 1080 APGLPGPPG-FGRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSR 1132 PG PG G G G+ G PG PG PG P G L GP G PGQPG PG + Sbjct: 754 TPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEG----LDGPRGDPGQPGPPGEQ 803 Score = 344 bits (883), Expect = 3e-94 Identities = 251/623 (40%), Positives = 294/623 (47%), Gaps = 84/623 (13%) Query: 556 GMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQ 615 G +G+ GPKG+ G G + G P +G G G + E LG G+ Sbjct: 830 GRRGKTGPKGDPGIPGLDRSGFPGETGSPG-IPGHQGEMGPLGQRGYPGNPG-------- 880 Query: 616 LLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLP 675 + GPPG G G+ G PG G GPPG+PG G G PG PG +GQ G GA G Sbjct: 881 -ILGPPGEDGVIGMMGFPGAIGPP---GPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQ 936 Query: 676 GMK------------GEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGP- 722 G K G+KG G G G G+ GNRG+PG PG KG G PG GPPGP Sbjct: 937 GDKGNPGPSEISHVIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPR 996 Query: 723 -----PGPPGPPG----PGCTMGLGFEDTEGSGSTQLLNEP-KLSRPTAAIGLKGEKGDR 772 G PG PG PG +G ++G T L P + RP GL G G + Sbjct: 997 GDLGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGT--LGFPGRAGRP----GLPGIHGLQ 1050 Query: 773 GPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGL-- 830 G KGE G + GPPGP G PG + G M P +GP GP+G Sbjct: 1051 GDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKK------GEMGQPGPPGHLGPAGPEGAPG 1104 Query: 831 -PGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGA 889 PG PG PG GP GD G G GL G G +G PG P MG +G+ G G Sbjct: 1105 SPGSPGLPGKPGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSP--GPMGIRGDQGRDGI 1162 Query: 890 PGPM-------------GPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGL 936 PGP GP+G PG +G G G PG PGL G KG GD G +GP G+ Sbjct: 1163 PGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAG--PRGPTGI 1220 Query: 937 PGPPGPPGPPGAVI-NIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLP 995 G PGPPG PGA+I G P R P PGS + G+KG+KGS G P Sbjct: 1221 EGFPGPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVI----GIKGDKGSMGHP 1276 Query: 996 GSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMS-GP 1054 G KG G G GPPG A L +G+ G +GF G KGEKG N FL S GP Sbjct: 1277 GPKGPPGTAGDMGPPGRL--GAPGTPGLPGPRGDPGFQGFPGVKGEKG--NPGFLGSIGP 1332 Query: 1055 PGLPGNPGPAGQKGE----TVVGPQGPPGAPGLPGPPGF-GRPGDPGPPGPPGPPGPPAI 1109 PG G GP G +G+ ++ G PG PG PG PG G PG PGPPG GP GP Sbjct: 1333 PGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGK 1392 Query: 1110 LGAAVALPGPPGPPGQPGLPGSR 1132 G PG PGP G+ G GS+ Sbjct: 1393 PGKD-GKPGTPGPAGEKGNKGSK 1414 Score = 343 bits (881), Expect = 5e-94 Identities = 278/783 (35%), Positives = 323/783 (41%), Gaps = 212/783 (27%) Query: 527 GSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEE------------- 573 G+ P GP P P R G G G KGE+G G++ Sbjct: 366 GARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGS 425 Query: 574 --LPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGS----GSGDLVGSEQLLRGP----PGP 623 LPG P P GP G + G +GS G G LL PGP Sbjct: 426 PGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGP 485 Query: 624 PGPPGLPG------IPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGV--------- 668 PG PGLPG IPG+ G G PGSPG G G PG PG +G PG+ Sbjct: 486 PGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQ 545 Query: 669 -DGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPG 727 +G G+PG G +G G G G G PG +GLPGP G+ +G G GPPG PG PG Sbjct: 546 PEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPG 605 Query: 728 PPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVG 787 PGP G +G EP L G G G+ GP+GE + + G Sbjct: 606 SPGPAGPAGPPGYGPQG--------EPGLQGTQGVPGAPGPPGEAGPRGELSVS-TPVPG 656 Query: 788 PPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGP------PGPDGLPGLPG--FPGP 839 PPGP GPPGH G IP +G PGPDG PG+PG FPGP Sbjct: 657 PPGPPGPPGH------------PGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGP 704 Query: 840 RGPKGDTGLPG---------------FPGLKGEQGEKGEPGAIL-----TEDIPLER--- 876 GPKGD G PG PG G G KGEP + T P ER Sbjct: 705 PGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNS 764 Query: 877 ----------LMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGR--------PGRPGLNG 918 L G G PG G GP G G PG GE G PGR G PGLNG Sbjct: 765 GEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNG 824 Query: 919 LKGT---------KGDPGVI---------MQGPPGLPGP---------------PGPPGP 945 LKG KGDPG+ G PG+PG PG GP Sbjct: 825 LKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGP 884 Query: 946 PG--AVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGD 1003 PG VI + G FP + P P +PG+P G+ G KG G PG+KGE+GD Sbjct: 885 PGEDGVIGMMG--FPGAIGP----PGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGD 938 Query: 1004 QGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGD--INGSFLMSGPPGLPGNP 1061 +G GP + + H + + KGE G KGF G GEKG+ + G + G GLPG Sbjct: 939 KGNPGP-------SEISHVIGD-KGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPA 990 Query: 1062 GPAGQKGETVVGPQGPPGAPGLPGPPGF----------------------GRPG------ 1093 GP G +G+ +G G PG PGL G PG GRPG Sbjct: 991 GPPGPRGD--LGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHG 1048 Query: 1094 --------------DPGPPGPPGPPGPPAILG--AAVALPGPPG------PPGQPGLPGS 1131 PGPPGP G PG P +G + PGPPG P G PG PGS Sbjct: 1049 LQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGS 1108 Query: 1132 RNL 1134 L Sbjct: 1109 PGL 1111 Score = 339 bits (870), Expect = 1e-92 Identities = 268/706 (37%), Positives = 311/706 (44%), Gaps = 153/706 (21%) Query: 527 GSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAG--------------- 571 G P DG P P R G+ G+ G KG+KGD G Sbjct: 297 GKPGKDGVP-----GFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQ 351 Query: 572 ----EELPGPPEPSG---PVGPTAGAEAEGS------GL----GWGSDVGS--------- 605 E PGPP P G P GP+ GS GL GW GS Sbjct: 352 EKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGK 411 Query: 606 ------GSGDLVGSEQLLRGPPGPPGPPG----LPGIPGKPGTDVFMGPPGSPGEDGPAG 655 GS GS L G PGPPGPPG G PG G ++G PG PG DGP G Sbjct: 412 DAMGTPGSPGCAGSPGL-PGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKG 470 Query: 656 EPGP--------PGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGK 707 EPG PGP G PG+ G G+ G+ G +GA G GS G PGN GLPG PG Sbjct: 471 EPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGS---PGSPGNTGLPGFPGF 527 Query: 708 KGQAGPPGVMGPPG----PPGPPGPPG-PGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAA 762 G G PG+ G G P G G PG PG G + +G T + L P Sbjct: 528 PGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKG--LPGPKGE 585 Query: 763 IGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELV 822 + L GEKGD+GP G+ G G+ GP GP GPPG+ G +P Sbjct: 586 LALSGEKGDQGPPGDPGSPGSP--GPAGPAGPPGYGP-------QGEPGLQGTQGVPGAP 636 Query: 823 GPPGPDGLPG-------LPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLE 875 GPPG G G +PG PGP GP G G G PG+ G G+ G+PG Sbjct: 637 GPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPG---------- 686 Query: 876 RLMGKKGEPGMHGA--PGPMGPKGP---PGHKGEFGLPGR---PGRPGLNGLKGTKGDPG 927 L G GEPG+ G PGP GPKG PG KG G PG+ PG PG GL G KG+P Sbjct: 687 -LPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPA 745 Query: 928 VIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKG 987 V M G PG PG PG G G I +P PG+P G +G Sbjct: 746 VAMPGGPGTPGFPGERGNSGEHGEIG-------------LPGLPGLPGTPGNEGLDGPRG 792 Query: 988 EKGSWGLPGSKGE-----KGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEK 1042 + G G PG +G +G +GAQG PG LN LKG+ G +G G KG+ Sbjct: 793 DPGQPGPPGEQGPPGRCIEGPRGAQGLPG-----------LNGLKGQQGRRGKTGPKGDP 841 Query: 1043 GDINGSFLMSGPPGLPGNPGPAGQKGET-VVGPQGPPGAPGLPGPPG----FGRPGDPGP 1097 G I G SG PG G+PG G +GE +G +G PG PG+ GPPG G G PG Sbjct: 842 G-IPG-LDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGA 899 Query: 1098 PGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNLVTAFSNMDD 1143 GPPGPPG P PG G PG PG+ G R A D Sbjct: 900 IGPPGPPGNPGT-------PGQRGSPGIPGVKGQRGTPGAKGEQGD 938 Score = 336 bits (861), Expect = 1e-91 Identities = 256/701 (36%), Positives = 302/701 (43%), Gaps = 145/701 (20%) Query: 548 TPAQREHVGMKGQAGPKGEKGDAGEE----LPGPPEPSGPVGPTAGAEAEGSGLGWGSDV 603 TP + G KG+ GEKGD G PG P P+GP GP GL V Sbjct: 573 TPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGV 632 Query: 604 GSGSGDL--------VGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAG 655 G + + GPPGPPGPPG PG G PG +G G PG GP G Sbjct: 633 PGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDG 692 Query: 656 EPG--------PPGPEG------------------QPGVDGATGLPGMKGEK-------- 681 EPG PPGP+G +PG+ G GLPG KGE Sbjct: 693 EPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP 752 Query: 682 ------GARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTM 735 G RG +G GE G PG GLPG PG +G GP G G PGPPG GPPG C Sbjct: 753 GTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGR-C-- 809 Query: 736 GLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPP 795 E G+ LN K G +G +G GPKG+ G+ G G PG G P Sbjct: 810 ---IEGPRGAQGLPGLNGLK--------GQQGRRGKTGPKGDPGIPGLDRSGFPGETGSP 858 Query: 796 GHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLK 855 G + + G + P ++GPPG DG+ G+ GFPG GP G G PG PG + Sbjct: 859 G---IPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQR 915 Query: 856 GEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPG 915 G G G G T G KGE G G PGP G KGE GL G G PG Sbjct: 916 GSPGIPGVKGQRGTP--------GAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPG 967 Query: 916 LNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPG 975 G +G G PG ++G GLPGP GPPGP G + + T +PG Sbjct: 968 EKGNRGVPGMPG--LKGLKGLPGPAGPPGPRGDLGS-------------------TGNPG 1006 Query: 976 SPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGE------ 1029 P L G+ G G+ G+PGSKG++G G G G P L + H L KGE Sbjct: 1007 EPGL---RGIPGSMGNMGMPGSKGKRGTLGFPGRAGRP-GLPGI-HGLQGDKGEPGYSEG 1061 Query: 1030 --------NGDKGFKGEKGEKGDIN--------------GSFLMSGPPGLPGNPGPAGQK 1067 GD G G+ G+KG++ G+ G PGLPG PGP G Sbjct: 1062 TRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDL 1121 Query: 1068 G----ETVVGP---QGPPGAPGLPGPPG-FGRPGDPGPPGPPGPPGPPAILGAAVALPGP 1119 G + ++GP +GPPG PG PG PG G GD G G PGP G G A PGP Sbjct: 1122 GFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGP 1181 Query: 1120 ------PGPPGQPGLPGSRNLVTAFSNMDDMLQKAHLVIEG 1154 G G G PG L M D + IEG Sbjct: 1182 RGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEG 1222 Score = 283 bits (724), Expect = 8e-76 Identities = 214/570 (37%), Positives = 257/570 (45%), Gaps = 90/570 (15%) Query: 527 GSPPPDGPPLPLPTVAPERWITPAQREHVGM---KGQAGPKGEKGDAGEE-LPGPPEPSG 582 G P GPP P P TP QR G+ KGQ G G KG+ G++ PGP E S Sbjct: 895 GFPGAIGPPGP-----PGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISH 949 Query: 583 PVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQL--LRGPPGPPGP---------PGLPG 631 +G +G G G + G + L L GP GPPGP PG PG Sbjct: 950 VIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG 1009 Query: 632 IPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGAR-----GP 686 + G PG+ MG G PG G G G PG G+PG+ G GL G KGE G GP Sbjct: 1010 LRGIPGS---MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGP 1066 Query: 687 NGSVGEKGDPGNRGL------PGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFE 740 G G+ G PG+ G PGPPG G AGP G G PG PG PG PGP LGF+ Sbjct: 1067 PGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGD--LGFK 1124 Query: 741 DTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKV 800 +G LL P + P G G G G +G++G DG I GP G +G G ++ Sbjct: 1125 GIKG-----LLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDG--IPGPAGEKGETGLLRA 1177 Query: 801 LSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGE 860 N P G G G PG PG PG +G GD G G G++G G Sbjct: 1178 PPGPRGN-----------PGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGP 1226 Query: 861 KGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMG-----------------PKGPPGHKG 903 G PGAI+ G +G PG G PGP G PKGPPG G Sbjct: 1227 PGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG 1286 Query: 904 EFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRP 963 + G PGR G PG GL G +GDPG QG PG+ G G PG G++ P P+ P Sbjct: 1287 DMGPPGRLGAPGTPGLPGPRGDPG--FQGFPGVKGEKGNPGFLGSIGP------PGPIGP 1338 Query: 964 HCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYL---- 1019 P PG+ ++I+ GS G PG+ GE G QG GPPGPP +L Sbjct: 1339 KGP-PGVRGDPGTLKIISL------PGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRG 1391 Query: 1020 RHFLNNLKGENGDKGFKGEKGEKGDINGSF 1049 + + G G G KG KG KG+ F Sbjct: 1392 KPGKDGKPGTPGPAGEKGNKGSKGEPESLF 1421 Score = 278 bits (710), Expect = 3e-74 Identities = 197/500 (39%), Positives = 237/500 (47%), Gaps = 63/500 (12%) Query: 663 EGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGP 722 +GQ DGA G KGEKG GP GS G+KG G GLPGP G KG G PG+ G G Sbjct: 36 KGQCFCDGAKG---EKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGV 92 Query: 723 PGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDG 782 G G PG SGS L P + P +G+ G G +G +G G+ G Sbjct: 93 RGISGLPG-------------FSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPG 139 Query: 783 ASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGP 842 +G PG G G +K + ++ P L G PGP GLPG PGFPGP GP Sbjct: 140 T--LGYPGIPGAAG-LKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP 196 Query: 843 KGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGP---- 898 G G GFPG G +G KG G ER++G KGE G+ G GP GP G Sbjct: 197 PGPPGFFGFPGAMGPRGPKGHMG---------ERVIGHKGERGVKGLTGPPGPPGTVIVT 247 Query: 899 ----------PGHKGEFGLPGRPGRPGLNGL--------KGTKGDPGVIMQGPPGLPGPP 940 G KG+ G G PG PG +GL KG GDPG +QG PG G P Sbjct: 248 LTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPG--LQGKPGKDGVP 305 Query: 941 GPPGPPGAVIN--IKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSK 998 G PG G N G + ++ G E + KG++G+ G PG + Sbjct: 306 GFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPR 365 Query: 999 GEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGD----INGSFLMSGP 1054 G +G QG GPPG P R L G G KG KGE+G G GS +G Sbjct: 366 GARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGS 425 Query: 1055 PGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPGFGRPGDPGPPGPPGPPGPPAILGAAV 1114 PGLPG+PGP G G+ +V +GPPG GLPG G PG PG GP G PG + Sbjct: 426 PGLPGSPGPPGPPGD-IVFRKGPPGDHGLPGY--LGSPGIPGVDGPKGEPG--LLCTQCP 480 Query: 1115 ALPGPPGPPGQPGLPGSRNL 1134 +PGPPG PG PGL G + + Sbjct: 481 YIPGPPGLPGLPGLHGVKGI 500 Score = 110 bits (276), Expect = 7e-24 Identities = 82/207 (39%), Positives = 96/207 (46%), Gaps = 35/207 (16%) Query: 523 GEESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGP--------KGEKGDAGEEL 574 G E PP P +P R P R G G GP KG+KG G Sbjct: 1219 GIEGFPGPPGLPGAIIPGQTGNRG-PPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPG 1277 Query: 575 P-GPPEPSGPVGPTAGAEAEGS-GL-GWGSDVG----------SGSGDLVGSEQLLRGPP 621 P GPP +G +GP A G+ GL G D G G+ +GS GPP Sbjct: 1278 PKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSI----GPP 1333 Query: 622 GPPGPPGLPGIPGKPGTDVFM------GPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLP 675 GP GP G PG+ G PGT + GPPG+PGE G GEPGPPGP G G G G P Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKP 1393 Query: 676 GMKGEKGARGPNGSVGEKGDPGNRGLP 702 G G+ G GP GEKG+ G++G P Sbjct: 1394 GKDGKPGTPGP---AGEKGNKGSKGEP 1417 Score = 84.3 bits (207), Expect = 7e-16 Identities = 60/162 (37%), Positives = 72/162 (44%), Gaps = 36/162 (22%) Query: 988 EKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDING 1047 +KG G+KGEKG++G GPPG P G KGF G +G G Sbjct: 35 DKGQCFCDGAKGEKGEKGFPGPPGSP-----------------GQKGFTGPEGLPGP--- 74 Query: 1048 SFLMSGPPGLPGNPGPAGQKG-ETVVGPQGPPGAPGLPGPPG----FGRPGDPGPPGPPG 1102 GP G PG PG G KG + G G G+PGLPG PG +G G PG G G Sbjct: 75 ----QGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKG 130 Query: 1103 PPGPPAILGAAVALPGPPGPPGQPGLPGSRNLVTAFSNMDDM 1144 G P LPG G PG PG G + A + +D+ Sbjct: 131 EQGFPG-------LPGTLGYPGIPGAAGLKGQKGAPAKEEDI 165 >gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo sapiens] Length = 1494 Score = 350 bits (897), Expect = 7e-96 Identities = 261/690 (37%), Positives = 291/690 (42%), Gaps = 174/690 (25%) Query: 558 KGQA---GPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSE 614 KGQ G KGEKG+ G PGPP G G T EG Sbjct: 36 KGQCFCDGAKGEKGEKG--FPGPPGSPGQKGFTG---PEG-------------------- 70 Query: 615 QLLRGPPGPPGPPGLP---------GIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQ 665 L GP GP G PGLP GI G PG G PG+PG GP G G PG G Sbjct: 71 --LPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGS 128 Query: 666 PGVDGATGLPGMKGEKGARGPNGSVGEKGDP-----------GNRGLPGPPGKKGQAGPP 714 G G GLPG G G G G G+KG P G+ GLPG PG +G GPP Sbjct: 129 KGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPP 188 Query: 715 GVMGPPGPPGPP---------GPPGPGCTMGLGFEDTEGSGSTQLLNEP---------KL 756 G GP GPPGPP GP GP MG +G + L P L Sbjct: 189 GFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTL 248 Query: 757 SRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGF-MNF 815 + P LKGEKGD+G GE GPPGP G PG ++G Sbjct: 249 TGPDNRTDLKGEKGDKGAMGE--------PGPPGPSGLPGE-----------SYGSEKGA 289 Query: 816 SDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPG----AILTED 871 P L G PG DG+PG PG G +G +G GL G G+KG++G+ G PG + Sbjct: 290 PGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDT 349 Query: 872 IPLERLMGKKGEPGMHGAPGPMGPKGPPGHKG-----EFGLPGRPGRPGLNGLKGTKGDP 926 + G G PG GA GP GP GPPG G GL G PG PGL G KG +G P Sbjct: 350 YQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRP 409 Query: 927 GVIMQ---------GPPGLPGPPGPPGPPGAVINIKG--------AIFPIPVRPH----- 964 G G PGLPG PGPPGPPG ++ KG P P Sbjct: 410 GKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPK 469 Query: 965 -------CKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLA 1017 + P PG P L HGVKG G G G KG G G G PG P Sbjct: 470 GEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFP---- 525 Query: 1018 YLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGP-------------- 1063 G GD G KGEKGE G + G PGL G PG Sbjct: 526 -------GFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKG 578 Query: 1064 -AGQKGETVV----GPQGPPGAPGLP---------GPPGFGRPGD---------PGPPGP 1100 G KGE + G QGPPG PG P GPPG+G G+ PG PGP Sbjct: 579 LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGP 638 Query: 1101 PGPPGPPAILGAAVALPGPPGPPGQPGLPG 1130 PG GP L + +PGPPGPPG PG PG Sbjct: 639 PGEAGPRGELSVSTPVPGPPGPPGPPGHPG 668 Score = 349 bits (896), Expect = 9e-96 Identities = 266/703 (37%), Positives = 313/703 (44%), Gaps = 130/703 (18%) Query: 525 ESGSPPPDGPPLPLPTVAPERWITP-AQREHVGMKGQAGPKGEKGDAG-------EELPG 576 E G P P G P PE P + G+ G G KG +G +G LPG Sbjct: 50 EKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPG 109 Query: 577 PPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKP 636 P +GP G GS G G L G PG PG GL G G P Sbjct: 110 TPGNTGPYGLVGVPGCSGS---------KGEQGFPGLPGTL-GYPGIPGAAGLKGQKGAP 159 Query: 637 GTDVFM-----GPPGSPGEDGPAGEPGPPG---PEGQPGVDGATGLPGMKGEKGARGPNG 688 + + G PG PG GP G PGPPG P G PG G G PG G +G +G G Sbjct: 160 AKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMG 219 Query: 689 S--VGEKGDPGNRGLPGPPGK-----------------KGQAGPPGVMGPPGPPGPPGPP 729 +G KG+ G +GL GPPG KG+ G G MG PGPPGP G P Sbjct: 220 ERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLP 279 Query: 730 GPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGAS----I 785 G G G L +P G +G KG+RG G G DG Sbjct: 280 GESYGSEKG-----APGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGD 334 Query: 786 VGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGD 845 +GPPG RGP + T G GP GP G PG+PG PG P G Sbjct: 335 IGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGAR---GPQGPSGPPGVPGSPGSSRP-GL 390 Query: 846 TGLPGFPGLKGEQGEKGEPG--AILTEDIPLERLMGKKGEPGMHGAPGPMGP-------K 896 G PG+PGLKG +GE+G PG A+ T P G G PG+ G+PGP GP K Sbjct: 391 RGAPGWPGLKGSKGERGRPGKDAMGTPGSP-----GCAGSPGLPGSPGPPGPPGDIVFRK 445 Query: 897 GPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAI 956 GPPG + GLPG G PG+ G+ G KG+PG++ P +PGPPG PG PG + +KG Sbjct: 446 GPPG---DHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG-LHGVKG-- 499 Query: 957 FPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGD----QGAQGPPGP 1012 IP R + PGSP G G G+ G PG KGEKG+ +G G PG Sbjct: 500 --IPGRQGAAGLKGS--PGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGD 555 Query: 1013 P-LDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPG---LPGNPGPAGQKG 1068 P L R L+ + G G KG G KGE ++G GPPG PG+PGPAG G Sbjct: 556 PGLRGQPGRKGLDGIPGTPGVKGLPGPKGELA-LSGEKGDQGPPGDPGSPGSPGPAGPAG 614 Query: 1069 ETVVGPQGPPG------APGLPGPPGF--------------GRPGDPGPPGPPGPPGPPA 1108 GPQG PG PG PGPPG G PG PGPPG PGP GPP Sbjct: 615 PPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPG 674 Query: 1109 ILGA-------------------AVALPGPPGPPGQPGLPGSR 1132 I G+ + PGPPGP G G PG++ Sbjct: 675 IPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTK 717 Score = 349 bits (895), Expect = 1e-95 Identities = 270/732 (36%), Positives = 314/732 (42%), Gaps = 154/732 (21%) Query: 527 GSPPPDGPP-LPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSGPVG 585 G P P GPP P P P P G G GP GE G G PGPP P G G Sbjct: 656 GPPGPPGPPGHPGPQGPPG---IPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQG 712 Query: 586 PTAGAEAEGSGLGWGSDVGSGSGDLVGSEQ----LLRGPPGPPG---------------P 626 + G G G L G++ + G PG PG Sbjct: 713 FPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGL 772 Query: 627 PGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPG-----PEGQPGVDGATGLPGMKGEK 681 PGLPG+PG PG + GP G PG+ GP GE GPPG P G G+ G GL G +G + Sbjct: 773 PGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRR 832 Query: 682 GARGPNGS-----------------------------VGEKGDPGNRGLPGPPGKKGQAG 712 G GP G +G++G PGN G+ GPPG+ G G Sbjct: 833 GKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIG 892 Query: 713 P---PGVMGPPGPPGPPGPPG----PGCTMGLGFEDTEGS-GSTQLLNEPKLSRPTAAIG 764 PG +GPPGPPG PG PG PG G T G+ G P S + IG Sbjct: 893 MMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIG 952 Query: 765 LKGEKG------DRGPKGERGMDGA----SIVGPPGPRGPPGHIKVLSNSLINITHGFMN 814 KGE G + G KG RG+ G + G PGP GPPG L G Sbjct: 953 DKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL---------GSTG 1003 Query: 815 FSDIPELVGPPGPDGLPGLPGFPGPRGP---KGDTGLPGFPGLKGEQGEKGEPGAIL--- 868 P L G PG G G+PG G RG G G PG PG+ G QG+KGEPG Sbjct: 1004 NPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTR 1063 Query: 869 ------TEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPG------L 916 T D L MGKKGE G G PG +GP GP G G G PG PG+PG Sbjct: 1064 PGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGF 1123 Query: 917 NGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGS 976 G+KG G PG+ +GPPGLPG PG PGP G + P P + + A PG Sbjct: 1124 KGIKGLLGPPGI--RGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGP 1181 Query: 977 PELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFK 1036 G KG++G+ G PG G KG G GP GP G +GF Sbjct: 1182 RGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGP-----------------TGIEGFP 1224 Query: 1037 GEKGEKGDI-NGSFLMSGPPGL---PGNPGPAGQKGETVVG------------PQGPPGA 1080 G G G I G GPPG PG PGP G G V+G P+GPPG Sbjct: 1225 GPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGT 1284 Query: 1081 PGLPGPPG-FGRPGDPGPPGPPGPPG------------PPAILGAAVALPGPPGPPGQP- 1126 G GPPG G PG PG PGP G PG P LG+ + PGP GP G P Sbjct: 1285 AGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGS-IGPPGPIGPKGPPG 1343 Query: 1127 --GLPGSRNLVT 1136 G PG+ +++ Sbjct: 1344 VRGDPGTLKIIS 1355 Score = 346 bits (888), Expect = 8e-95 Identities = 264/687 (38%), Positives = 306/687 (44%), Gaps = 144/687 (20%) Query: 556 GMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQ 615 G G G G +GD G+ PGPP GP G GL G L G +Q Sbjct: 780 GTPGNEGLDGPRGDPGQ--PGPPGEQGPPGRCIEGPRGAQGL-------PGLNGLKG-QQ 829 Query: 616 LLRGPPGPPGPPGLPGI-----------PGKPGTDVFMGP------PGSPGEDGPAGE-- 656 RG GP G PG+PG+ PG PG MGP PG+PG GP GE Sbjct: 830 GRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDG 889 Query: 657 -------------PGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPG------ 697 PGPPG G PG G+ G+PG+KG++G G G G+KG+PG Sbjct: 890 VIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISH 949 Query: 698 ---------------------NRGLPGPPGKKGQAGPPGVMGPPGPPGP------PGPPG 730 NRG+PG PG KG G PG GPPGP G PG PG Sbjct: 950 VIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG 1009 Query: 731 ----PGCTMGLGFEDTEGSGSTQLLNEP-KLSRPTAAIGLKGEKGDRGPKGERGMDGASI 785 PG +G ++G T L P + RP GL G G +G KGE G + Sbjct: 1010 LRGIPGSMGNMGMPGSKGKRGT--LGFPGRAGRP----GLPGIHGLQGDKGEPGYSEGTR 1063 Query: 786 VGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPG---FPGPRGP 842 GPPGP G PG + G M P +GP GP+G PG PG PG GP Sbjct: 1064 PGPPGPTGDPGLPGDMGKK------GEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGP 1117 Query: 843 KGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMG-------- 894 GD G G GL G G +G PG P MG +G+ G G PGP G Sbjct: 1118 HGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP--MGIRGDQGRDGIPGPAGEKGETGLL 1175 Query: 895 -----PKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAV 949 P+G PG +G G G PG PGL G KG GD G +GP G+ G PGPPG PGA+ Sbjct: 1176 RAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGP--RGPTGIEGFPGPPGLPGAI 1233 Query: 950 I-NIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQG 1008 I G P R P PGS + G+KG+KGS G PG KG G G G Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVI----GIKGDKGSMGHPGPKGPPGTAGDMG 1289 Query: 1009 PPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMS-GPPGLPGNPGPAGQK 1067 PPG A L +G+ G +GF G KGEKG N FL S GPPG G GP G + Sbjct: 1290 PPGRLG--APGTPGLPGPRGDPGFQGFPGVKGEKG--NPGFLGSIGPPGPIGPKGPPGVR 1345 Query: 1068 GET----VVGPQGPPGAPGLPGPPGF-GRPGDPGPPG---------------PPGPPGPP 1107 G+ ++ G PG PG PG PG G PG PGPPG PG PGP Sbjct: 1346 GDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPA 1405 Query: 1108 AILG--AAVALPGPPGPPGQPGLPGSR 1132 G + PGP G G PGL G R Sbjct: 1406 GEKGNKGSKGEPGPAGSDGLPGLKGKR 1432 Score = 345 bits (885), Expect = 2e-94 Identities = 255/714 (35%), Positives = 304/714 (42%), Gaps = 153/714 (21%) Query: 503 PGDEEDLAAATTEEPLITAGGEESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAG 562 P EED+ +P + G P P G P P+ P + G G G Sbjct: 159 PAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFF--------GFPGAMG 210 Query: 563 PKGEKGDAGEELPGPPEP------SGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQL 616 P+G KG GE + G +GP GP +G +D+ GD Sbjct: 211 PRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGD------- 263 Query: 617 LRGPPGPPGPPGLPGIPGKP-GTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLP 675 +G G PGPPG G+PG+ G++ G PG PG G G+ G PG G GV G G P Sbjct: 264 -KGAMGEPGPPGPSGLPGESYGSE--KGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFP 320 Query: 676 GMKGEKGARGPNGSVGEKG------------DPGNRGLPGPPGKKGQAGPPGVMGPPGPP 723 G+ GE G +G G +G G + G+ G PGPPG +G GP G GPPG P Sbjct: 321 GLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVP 380 Query: 724 GPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGM--- 780 G PG PG G+ GLKG KG+RG G+ M Sbjct: 381 GSPGSSRPGLRGAPGWP-----------------------GLKGSKGERGRPGKDAMGTP 417 Query: 781 ------DGASIVGPPGPRGPPGHIKVLSNSL-INITHGFMNFSDIPELVGP--------- 824 + G PGP GPPG I + G++ IP + GP Sbjct: 418 GSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCT 477 Query: 825 -----PGPDGLPGLPGFPGPR---------------GPKGDTGLPGFPGLKGEQGE---K 861 PGP GLPGLPG G + G G+TGLPGFPG G QG+ K Sbjct: 478 QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK 537 Query: 862 GEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKG 921 GE G E + E +G G+PG+ G PG G G PG G GLPG G L+G KG Sbjct: 538 GEKG----ETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKG 593 Query: 922 TKGDPGVIMQGPPGLPGPPGPPGPPG----------AVINIKGAIFPI-PVRPHCKMPVD 970 +G PG G PG PGP GP GPPG + GA P P ++ V Sbjct: 594 DQGPPG--DPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVS 651 Query: 971 TAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGP-----------PGPPLDLAYL 1019 T PG P G G +G G+PGS G+ GD G GP PGPP Sbjct: 652 TPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPP------ 705 Query: 1020 RHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPG 1079 G GD+GF G KG G G PGLPG PG G KGE V G PG Sbjct: 706 --------GPKGDQGFPGTKGSLGCPG----KMGEPGLPGKPGLPGAKGEPAVAMPGGPG 753 Query: 1080 APGLPGPPG-FGRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSR 1132 PG PG G G G+ G PG PG PG P G L GP G PGQPG PG + Sbjct: 754 TPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEG----LDGPRGDPGQPGPPGEQ 803 Score = 343 bits (881), Expect = 5e-94 Identities = 278/783 (35%), Positives = 323/783 (41%), Gaps = 212/783 (27%) Query: 527 GSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEE------------- 573 G+ P GP P P R G G G KGE+G G++ Sbjct: 366 GARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGS 425 Query: 574 --LPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGS----GSGDLVGSEQLLRGP----PGP 623 LPG P P GP G + G +GS G G LL PGP Sbjct: 426 PGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGP 485 Query: 624 PGPPGLPG------IPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGV--------- 668 PG PGLPG IPG+ G G PGSPG G G PG PG +G PG+ Sbjct: 486 PGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQ 545 Query: 669 -DGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPG 727 +G G+PG G +G G G G G PG +GLPGP G+ +G G GPPG PG PG Sbjct: 546 PEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPG 605 Query: 728 PPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVG 787 PGP G +G EP L G G G+ GP+GE + + G Sbjct: 606 SPGPAGPAGPPGYGPQG--------EPGLQGTQGVPGAPGPPGEAGPRGELSVS-TPVPG 656 Query: 788 PPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGP------PGPDGLPGLPG--FPGP 839 PPGP GPPGH G IP +G PGPDG PG+PG FPGP Sbjct: 657 PPGPPGPPGH------------PGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGP 704 Query: 840 RGPKGDTGLPG---------------FPGLKGEQGEKGEPGAIL-----TEDIPLER--- 876 GPKGD G PG PG G G KGEP + T P ER Sbjct: 705 PGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNS 764 Query: 877 ----------LMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGR--------PGRPGLNG 918 L G G PG G GP G G PG GE G PGR G PGLNG Sbjct: 765 GEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNG 824 Query: 919 LKGT---------KGDPGVI---------MQGPPGLPGP---------------PGPPGP 945 LKG KGDPG+ G PG+PG PG GP Sbjct: 825 LKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGP 884 Query: 946 PG--AVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGD 1003 PG VI + G FP + P P +PG+P G+ G KG G PG+KGE+GD Sbjct: 885 PGEDGVIGMMG--FPGAIGP----PGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGD 938 Query: 1004 QGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGD--INGSFLMSGPPGLPGNP 1061 +G GP + + H + + KGE G KGF G GEKG+ + G + G GLPG Sbjct: 939 KGNPGP-------SEISHVIGD-KGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPA 990 Query: 1062 GPAGQKGETVVGPQGPPGAPGLPGPPGF----------------------GRPG------ 1093 GP G +G+ +G G PG PGL G PG GRPG Sbjct: 991 GPPGPRGD--LGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHG 1048 Query: 1094 --------------DPGPPGPPGPPGPPAILG--AAVALPGPPG------PPGQPGLPGS 1131 PGPPGP G PG P +G + PGPPG P G PG PGS Sbjct: 1049 LQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGS 1108 Query: 1132 RNL 1134 L Sbjct: 1109 PGL 1111 Score = 339 bits (870), Expect = 1e-92 Identities = 268/706 (37%), Positives = 311/706 (44%), Gaps = 153/706 (21%) Query: 527 GSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAG--------------- 571 G P DG P P R G+ G+ G KG+KGD G Sbjct: 297 GKPGKDGVP-----GFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQ 351 Query: 572 ----EELPGPPEPSG---PVGPTAGAEAEGS------GL----GWGSDVGS--------- 605 E PGPP P G P GP+ GS GL GW GS Sbjct: 352 EKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGK 411 Query: 606 ------GSGDLVGSEQLLRGPPGPPGPPG----LPGIPGKPGTDVFMGPPGSPGEDGPAG 655 GS GS L G PGPPGPPG G PG G ++G PG PG DGP G Sbjct: 412 DAMGTPGSPGCAGSPGL-PGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKG 470 Query: 656 EPGP--------PGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGK 707 EPG PGP G PG+ G G+ G+ G +GA G GS G PGN GLPG PG Sbjct: 471 EPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGS---PGSPGNTGLPGFPGF 527 Query: 708 KGQAGPPGVMGPPG----PPGPPGPPG-PGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAA 762 G G PG+ G G P G G PG PG G + +G T + L P Sbjct: 528 PGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKG--LPGPKGE 585 Query: 763 IGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELV 822 + L GEKGD+GP G+ G G+ GP GP GPPG+ G +P Sbjct: 586 LALSGEKGDQGPPGDPGSPGSP--GPAGPAGPPGYGP-------QGEPGLQGTQGVPGAP 636 Query: 823 GPPGPDGLPG-------LPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLE 875 GPPG G G +PG PGP GP G G G PG+ G G+ G+PG Sbjct: 637 GPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPG---------- 686 Query: 876 RLMGKKGEPGMHGA--PGPMGPKGP---PGHKGEFGLPGR---PGRPGLNGLKGTKGDPG 927 L G GEPG+ G PGP GPKG PG KG G PG+ PG PG GL G KG+P Sbjct: 687 -LPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPA 745 Query: 928 VIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKG 987 V M G PG PG PG G G I +P PG+P G +G Sbjct: 746 VAMPGGPGTPGFPGERGNSGEHGEIG-------------LPGLPGLPGTPGNEGLDGPRG 792 Query: 988 EKGSWGLPGSKGE-----KGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEK 1042 + G G PG +G +G +GAQG PG LN LKG+ G +G G KG+ Sbjct: 793 DPGQPGPPGEQGPPGRCIEGPRGAQGLPG-----------LNGLKGQQGRRGKTGPKGDP 841 Query: 1043 GDINGSFLMSGPPGLPGNPGPAGQKGET-VVGPQGPPGAPGLPGPPG----FGRPGDPGP 1097 G I G SG PG G+PG G +GE +G +G PG PG+ GPPG G G PG Sbjct: 842 G-IPG-LDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGA 899 Query: 1098 PGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNLVTAFSNMDD 1143 GPPGPPG P PG G PG PG+ G R A D Sbjct: 900 IGPPGPPGNPGT-------PGQRGSPGIPGVKGQRGTPGAKGEQGD 938 Score = 336 bits (861), Expect = 1e-91 Identities = 256/701 (36%), Positives = 302/701 (43%), Gaps = 145/701 (20%) Query: 548 TPAQREHVGMKGQAGPKGEKGDAGEE----LPGPPEPSGPVGPTAGAEAEGSGLGWGSDV 603 TP + G KG+ GEKGD G PG P P+GP GP GL V Sbjct: 573 TPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGV 632 Query: 604 GSGSGDL--------VGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAG 655 G + + GPPGPPGPPG PG G PG +G G PG GP G Sbjct: 633 PGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDG 692 Query: 656 EPG--------PPGPEG------------------QPGVDGATGLPGMKGEK-------- 681 EPG PPGP+G +PG+ G GLPG KGE Sbjct: 693 EPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP 752 Query: 682 ------GARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTM 735 G RG +G GE G PG GLPG PG +G GP G G PGPPG GPPG C Sbjct: 753 GTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGR-C-- 809 Query: 736 GLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPP 795 E G+ LN K G +G +G GPKG+ G+ G G PG G P Sbjct: 810 ---IEGPRGAQGLPGLNGLK--------GQQGRRGKTGPKGDPGIPGLDRSGFPGETGSP 858 Query: 796 GHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLK 855 G + + G + P ++GPPG DG+ G+ GFPG GP G G PG PG + Sbjct: 859 G---IPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQR 915 Query: 856 GEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPG 915 G G G G T G KGE G G PGP G KGE GL G G PG Sbjct: 916 GSPGIPGVKGQRGTP--------GAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPG 967 Query: 916 LNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPG 975 G +G G PG ++G GLPGP GPPGP G + + T +PG Sbjct: 968 EKGNRGVPGMPG--LKGLKGLPGPAGPPGPRGDLGS-------------------TGNPG 1006 Query: 976 SPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGE------ 1029 P L G+ G G+ G+PGSKG++G G G G P L + H L KGE Sbjct: 1007 EPGL---RGIPGSMGNMGMPGSKGKRGTLGFPGRAGRP-GLPGI-HGLQGDKGEPGYSEG 1061 Query: 1030 --------NGDKGFKGEKGEKGDIN--------------GSFLMSGPPGLPGNPGPAGQK 1067 GD G G+ G+KG++ G+ G PGLPG PGP G Sbjct: 1062 TRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDL 1121 Query: 1068 G----ETVVGP---QGPPGAPGLPGPPG-FGRPGDPGPPGPPGPPGPPAILGAAVALPGP 1119 G + ++GP +GPPG PG PG PG G GD G G PGP G G A PGP Sbjct: 1122 GFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGP 1181 Query: 1120 ------PGPPGQPGLPGSRNLVTAFSNMDDMLQKAHLVIEG 1154 G G G PG L M D + IEG Sbjct: 1182 RGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEG 1222 Score = 285 bits (728), Expect = 3e-76 Identities = 213/586 (36%), Positives = 261/586 (44%), Gaps = 113/586 (19%) Query: 527 GSPPPDGPPLPLPTVAPERWITPAQREHVGM---KGQAGPKGEKGDAGEE-LPGPPEPSG 582 G P GPP P P TP QR G+ KGQ G G KG+ G++ PGP E S Sbjct: 895 GFPGAIGPPGP-----PGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISH 949 Query: 583 PVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQL--LRGPPGPPGP---------PGLPG 631 +G +G G G + G + L L GP GPPGP PG PG Sbjct: 950 VIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG 1009 Query: 632 IPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGAR-----GP 686 + G PG+ MG G PG G G G PG G+PG+ G GL G KGE G GP Sbjct: 1010 LRGIPGS---MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGP 1066 Query: 687 NGSVGEKGDPGNRGL------PGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFE 740 G G+ G PG+ G PGPPG G AGP G G PG PG PG PGP LGF+ Sbjct: 1067 PGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGD--LGFK 1124 Query: 741 DTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKV 800 +G LL P + P G G G G +G++G DG I GP G +G G ++ Sbjct: 1125 GIKG-----LLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDG--IPGPAGEKGETGLLRA 1177 Query: 801 LSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGE 860 N P G G G PG PG PG +G GD G G G++G G Sbjct: 1178 PPGPRGN-----------PGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGP 1226 Query: 861 KGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMG-----------------PKGPPGHKG 903 G PGAI+ G +G PG G PGP G PKGPPG G Sbjct: 1227 PGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG 1286 Query: 904 EFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGL---------------PGPPGPPGPPGA 948 + G PGR G PG GL G +GDPG QG PG+ PGP GP GPPG Sbjct: 1287 DMGPPGRLGAPGTPGLPGPRGDPG--FQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGV 1344 Query: 949 --------VINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKG- 999 +I++ G+ P M + PG P + G +G+ G G PG+ G Sbjct: 1345 RGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGP 1404 Query: 1000 --EKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKG 1043 EKG++G++G PGP G +G G KG++G+ G Sbjct: 1405 AGEKGNKGSKGEPGP--------------AGSDGLPGLKGKRGDSG 1436 Score = 278 bits (710), Expect = 3e-74 Identities = 197/500 (39%), Positives = 237/500 (47%), Gaps = 63/500 (12%) Query: 663 EGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGP 722 +GQ DGA G KGEKG GP GS G+KG G GLPGP G KG G PG+ G G Sbjct: 36 KGQCFCDGAKG---EKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGV 92 Query: 723 PGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDG 782 G G PG SGS L P + P +G+ G G +G +G G+ G Sbjct: 93 RGISGLPG-------------FSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPG 139 Query: 783 ASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGP 842 +G PG G G +K + ++ P L G PGP GLPG PGFPGP GP Sbjct: 140 T--LGYPGIPGAAG-LKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP 196 Query: 843 KGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGP---- 898 G G GFPG G +G KG G ER++G KGE G+ G GP GP G Sbjct: 197 PGPPGFFGFPGAMGPRGPKGHMG---------ERVIGHKGERGVKGLTGPPGPPGTVIVT 247 Query: 899 ----------PGHKGEFGLPGRPGRPGLNGL--------KGTKGDPGVIMQGPPGLPGPP 940 G KG+ G G PG PG +GL KG GDPG +QG PG G P Sbjct: 248 LTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPG--LQGKPGKDGVP 305 Query: 941 GPPGPPGAVIN--IKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSK 998 G PG G N G + ++ G E + KG++G+ G PG + Sbjct: 306 GFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPR 365 Query: 999 GEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGD----INGSFLMSGP 1054 G +G QG GPPG P R L G G KG KGE+G G GS +G Sbjct: 366 GARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGS 425 Query: 1055 PGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPGFGRPGDPGPPGPPGPPGPPAILGAAV 1114 PGLPG+PGP G G+ +V +GPPG GLPG G PG PG GP G PG + Sbjct: 426 PGLPGSPGPPGPPGD-IVFRKGPPGDHGLPGY--LGSPGIPGVDGPKGEPG--LLCTQCP 480 Query: 1115 ALPGPPGPPGQPGLPGSRNL 1134 +PGPPG PG PGL G + + Sbjct: 481 YIPGPPGLPGLPGLHGVKGI 500 Score = 256 bits (655), Expect = 8e-68 Identities = 179/456 (39%), Positives = 204/456 (44%), Gaps = 97/456 (21%) Query: 556 GMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQ 615 G G G G+KG+ G+ PGPP GP GP + GS G G G + Sbjct: 1071 GDPGLPGDMGKKGEMGQ--PGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKG 1128 Query: 616 LLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPG-------PPGPEGQPGV 668 LL GPPG GPPGLPG PG PG G G G GPAGE G PPGP G PG Sbjct: 1129 LL-GPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGA 1187 Query: 669 DGATG---------LPGMKGEKGARGPNGSVGEKGDPGNRGLPGP--PGKKGQAGPPGVM 717 GA G LPG KG G GP G G +G PG GLPG PG+ G GPPG Sbjct: 1188 QGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSR 1247 Query: 718 GPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGE 777 G PG PGPPGPPG + IG+KG+KG G G Sbjct: 1248 GSPGAPGPPGPPG-----------------------------SHVIGIKGDKGSMGHPGP 1278 Query: 778 RGMDG-ASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGF 836 +G G A +GPPG G PG G PGP G PG GF Sbjct: 1279 KGPPGTAGDMGPPGRLGAPG------------------------TPGLPGPRGDPGFQGF 1314 Query: 837 PGPRGPKGDTGL------PGFPGLKGEQGEKGEPGAILTEDIP-LERLMGKKGEPGMHGA 889 PG +G KG+ G PG G KG G +G+PG + +P G GEPGM G Sbjct: 1315 PGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGE 1374 Query: 890 PGP------MGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVI-MQGPPGLPGPPGP 942 PGP +GP GP G G+ G PG PG G G KG+KG+PG G PGL G G Sbjct: 1375 PGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGD 1434 Query: 943 PGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPE 978 G P A +G +F + TA P PE Sbjct: 1435 SGSP-ATWTTRGFVF-------TRHSQTTAIPSCPE 1462 Score = 126 bits (317), Expect = 1e-28 Identities = 91/228 (39%), Positives = 105/228 (46%), Gaps = 35/228 (15%) Query: 523 GEESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGP--------KGEKGDAGEEL 574 G E PP P +P R P R G G GP KG+KG G Sbjct: 1219 GIEGFPGPPGLPGAIIPGQTGNRG-PPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPG 1277 Query: 575 P-GPPEPSGPVGPTAGAEAEGS-GL-GWGSDVG----------SGSGDLVGSEQLLRGPP 621 P GPP +G +GP A G+ GL G D G G+ +GS GPP Sbjct: 1278 PKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSI----GPP 1333 Query: 622 GPPGPPGLPGIPGKPGTDVFM------GPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLP 675 GP GP G PG+ G PGT + GPPG+PGE G GEPGPPGP G G G G P Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKP 1393 Query: 676 GMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPP 723 G G+ G GP GEKG+ G++G PGP G G G G G G P Sbjct: 1394 GKDGKPGTPGP---AGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438 Score = 84.3 bits (207), Expect = 7e-16 Identities = 60/162 (37%), Positives = 72/162 (44%), Gaps = 36/162 (22%) Query: 988 EKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDING 1047 +KG G+KGEKG++G GPPG P G KGF G +G G Sbjct: 35 DKGQCFCDGAKGEKGEKGFPGPPGSP-----------------GQKGFTGPEGLPGP--- 74 Query: 1048 SFLMSGPPGLPGNPGPAGQKG-ETVVGPQGPPGAPGLPGPPG----FGRPGDPGPPGPPG 1102 GP G PG PG G KG + G G G+PGLPG PG +G G PG G G Sbjct: 75 ----QGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKG 130 Query: 1103 PPGPPAILGAAVALPGPPGPPGQPGLPGSRNLVTAFSNMDDM 1144 G P LPG G PG PG G + A + +D+ Sbjct: 131 EQGFPG-------LPGTLGYPGIPGAAGLKGQKGAPAKEEDI 165 >gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo sapiens] Length = 1637 Score = 350 bits (897), Expect = 7e-96 Identities = 261/690 (37%), Positives = 291/690 (42%), Gaps = 174/690 (25%) Query: 558 KGQA---GPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSE 614 KGQ G KGEKG+ G PGPP G G T EG Sbjct: 36 KGQCFCDGAKGEKGEKG--FPGPPGSPGQKGFTG---PEG-------------------- 70 Query: 615 QLLRGPPGPPGPPGLP---------GIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQ 665 L GP GP G PGLP GI G PG G PG+PG GP G G PG G Sbjct: 71 --LPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGS 128 Query: 666 PGVDGATGLPGMKGEKGARGPNGSVGEKGDP-----------GNRGLPGPPGKKGQAGPP 714 G G GLPG G G G G G+KG P G+ GLPG PG +G GPP Sbjct: 129 KGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPP 188 Query: 715 GVMGPPGPPGPP---------GPPGPGCTMGLGFEDTEGSGSTQLLNEP---------KL 756 G GP GPPGPP GP GP MG +G + L P L Sbjct: 189 GFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTL 248 Query: 757 SRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGF-MNF 815 + P LKGEKGD+G GE GPPGP G PG ++G Sbjct: 249 TGPDNRTDLKGEKGDKGAMGE--------PGPPGPSGLPGE-----------SYGSEKGA 289 Query: 816 SDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPG----AILTED 871 P L G PG DG+PG PG G +G +G GL G G+KG++G+ G PG + Sbjct: 290 PGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDT 349 Query: 872 IPLERLMGKKGEPGMHGAPGPMGPKGPPGHKG-----EFGLPGRPGRPGLNGLKGTKGDP 926 + G G PG GA GP GP GPPG G GL G PG PGL G KG +G P Sbjct: 350 YQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRP 409 Query: 927 GVIMQ---------GPPGLPGPPGPPGPPGAVINIKG--------AIFPIPVRPH----- 964 G G PGLPG PGPPGPPG ++ KG P P Sbjct: 410 GKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPK 469 Query: 965 -------CKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLA 1017 + P PG P L HGVKG G G G KG G G G PG P Sbjct: 470 GEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFP---- 525 Query: 1018 YLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGP-------------- 1063 G GD G KGEKGE G + G PGL G PG Sbjct: 526 -------GFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKG 578 Query: 1064 -AGQKGETVV----GPQGPPGAPGLP---------GPPGFGRPGD---------PGPPGP 1100 G KGE + G QGPPG PG P GPPG+G G+ PG PGP Sbjct: 579 LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGP 638 Query: 1101 PGPPGPPAILGAAVALPGPPGPPGQPGLPG 1130 PG GP L + +PGPPGPPG PG PG Sbjct: 639 PGEAGPRGELSVSTPVPGPPGPPGPPGHPG 668 Score = 349 bits (896), Expect = 9e-96 Identities = 266/703 (37%), Positives = 313/703 (44%), Gaps = 130/703 (18%) Query: 525 ESGSPPPDGPPLPLPTVAPERWITP-AQREHVGMKGQAGPKGEKGDAG-------EELPG 576 E G P P G P PE P + G+ G G KG +G +G LPG Sbjct: 50 EKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPG 109 Query: 577 PPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKP 636 P +GP G GS G G L G PG PG GL G G P Sbjct: 110 TPGNTGPYGLVGVPGCSGS---------KGEQGFPGLPGTL-GYPGIPGAAGLKGQKGAP 159 Query: 637 GTDVFM-----GPPGSPGEDGPAGEPGPPG---PEGQPGVDGATGLPGMKGEKGARGPNG 688 + + G PG PG GP G PGPPG P G PG G G PG G +G +G G Sbjct: 160 AKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMG 219 Query: 689 S--VGEKGDPGNRGLPGPPGK-----------------KGQAGPPGVMGPPGPPGPPGPP 729 +G KG+ G +GL GPPG KG+ G G MG PGPPGP G P Sbjct: 220 ERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLP 279 Query: 730 GPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGAS----I 785 G G G L +P G +G KG+RG G G DG Sbjct: 280 GESYGSEKG-----APGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGD 334 Query: 786 VGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGD 845 +GPPG RGP + T G GP GP G PG+PG PG P G Sbjct: 335 IGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGAR---GPQGPSGPPGVPGSPGSSRP-GL 390 Query: 846 TGLPGFPGLKGEQGEKGEPG--AILTEDIPLERLMGKKGEPGMHGAPGPMGP-------K 896 G PG+PGLKG +GE+G PG A+ T P G G PG+ G+PGP GP K Sbjct: 391 RGAPGWPGLKGSKGERGRPGKDAMGTPGSP-----GCAGSPGLPGSPGPPGPPGDIVFRK 445 Query: 897 GPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAI 956 GPPG + GLPG G PG+ G+ G KG+PG++ P +PGPPG PG PG + +KG Sbjct: 446 GPPG---DHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG-LHGVKG-- 499 Query: 957 FPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGD----QGAQGPPGP 1012 IP R + PGSP G G G+ G PG KGEKG+ +G G PG Sbjct: 500 --IPGRQGAAGLKGS--PGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGD 555 Query: 1013 P-LDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPG---LPGNPGPAGQKG 1068 P L R L+ + G G KG G KGE ++G GPPG PG+PGPAG G Sbjct: 556 PGLRGQPGRKGLDGIPGTPGVKGLPGPKGELA-LSGEKGDQGPPGDPGSPGSPGPAGPAG 614 Query: 1069 ETVVGPQGPPG------APGLPGPPGF--------------GRPGDPGPPGPPGPPGPPA 1108 GPQG PG PG PGPPG G PG PGPPG PGP GPP Sbjct: 615 PPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPG 674 Query: 1109 ILGA-------------------AVALPGPPGPPGQPGLPGSR 1132 I G+ + PGPPGP G G PG++ Sbjct: 675 IPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTK 717 Score = 349 bits (895), Expect = 1e-95 Identities = 270/732 (36%), Positives = 314/732 (42%), Gaps = 154/732 (21%) Query: 527 GSPPPDGPP-LPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSGPVG 585 G P P GPP P P P P G G GP GE G G PGPP P G G Sbjct: 656 GPPGPPGPPGHPGPQGPPG---IPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQG 712 Query: 586 PTAGAEAEGSGLGWGSDVGSGSGDLVGSEQ----LLRGPPGPPG---------------P 626 + G G G L G++ + G PG PG Sbjct: 713 FPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGL 772 Query: 627 PGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPG-----PEGQPGVDGATGLPGMKGEK 681 PGLPG+PG PG + GP G PG+ GP GE GPPG P G G+ G GL G +G + Sbjct: 773 PGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRR 832 Query: 682 GARGPNGS-----------------------------VGEKGDPGNRGLPGPPGKKGQAG 712 G GP G +G++G PGN G+ GPPG+ G G Sbjct: 833 GKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIG 892 Query: 713 P---PGVMGPPGPPGPPGPPG----PGCTMGLGFEDTEGS-GSTQLLNEPKLSRPTAAIG 764 PG +GPPGPPG PG PG PG G T G+ G P S + IG Sbjct: 893 MMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIG 952 Query: 765 LKGEKG------DRGPKGERGMDGA----SIVGPPGPRGPPGHIKVLSNSLINITHGFMN 814 KGE G + G KG RG+ G + G PGP GPPG L G Sbjct: 953 DKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL---------GSTG 1003 Query: 815 FSDIPELVGPPGPDGLPGLPGFPGPRGP---KGDTGLPGFPGLKGEQGEKGEPGAIL--- 868 P L G PG G G+PG G RG G G PG PG+ G QG+KGEPG Sbjct: 1004 NPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTR 1063 Query: 869 ------TEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPG------L 916 T D L MGKKGE G G PG +GP GP G G G PG PG+PG Sbjct: 1064 PGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGF 1123 Query: 917 NGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGS 976 G+KG G PG+ +GPPGLPG PG PGP G + P P + + A PG Sbjct: 1124 KGIKGLLGPPGI--RGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGP 1181 Query: 977 PELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFK 1036 G KG++G+ G PG G KG G GP GP G +GF Sbjct: 1182 RGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGP-----------------TGIEGFP 1224 Query: 1037 GEKGEKGDI-NGSFLMSGPPGL---PGNPGPAGQKGETVVG------------PQGPPGA 1080 G G G I G GPPG PG PGP G G V+G P+GPPG Sbjct: 1225 GPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGT 1284 Query: 1081 PGLPGPPG-FGRPGDPGPPGPPGPPG------------PPAILGAAVALPGPPGPPGQP- 1126 G GPPG G PG PG PGP G PG P LG+ + PGP GP G P Sbjct: 1285 AGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGS-IGPPGPIGPKGPPG 1343 Query: 1127 --GLPGSRNLVT 1136 G PG+ +++ Sbjct: 1344 VRGDPGTLKIIS 1355 Score = 346 bits (888), Expect = 8e-95 Identities = 264/687 (38%), Positives = 306/687 (44%), Gaps = 144/687 (20%) Query: 556 GMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQ 615 G G G G +GD G+ PGPP GP G GL G L G +Q Sbjct: 780 GTPGNEGLDGPRGDPGQ--PGPPGEQGPPGRCIEGPRGAQGL-------PGLNGLKG-QQ 829 Query: 616 LLRGPPGPPGPPGLPGI-----------PGKPGTDVFMGP------PGSPGEDGPAGE-- 656 RG GP G PG+PG+ PG PG MGP PG+PG GP GE Sbjct: 830 GRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDG 889 Query: 657 -------------PGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPG------ 697 PGPPG G PG G+ G+PG+KG++G G G G+KG+PG Sbjct: 890 VIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISH 949 Query: 698 ---------------------NRGLPGPPGKKGQAGPPGVMGPPGPPGP------PGPPG 730 NRG+PG PG KG G PG GPPGP G PG PG Sbjct: 950 VIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG 1009 Query: 731 ----PGCTMGLGFEDTEGSGSTQLLNEP-KLSRPTAAIGLKGEKGDRGPKGERGMDGASI 785 PG +G ++G T L P + RP GL G G +G KGE G + Sbjct: 1010 LRGIPGSMGNMGMPGSKGKRGT--LGFPGRAGRP----GLPGIHGLQGDKGEPGYSEGTR 1063 Query: 786 VGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPG---FPGPRGP 842 GPPGP G PG + G M P +GP GP+G PG PG PG GP Sbjct: 1064 PGPPGPTGDPGLPGDMGKK------GEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGP 1117 Query: 843 KGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMG-------- 894 GD G G GL G G +G PG P MG +G+ G G PGP G Sbjct: 1118 HGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP--MGIRGDQGRDGIPGPAGEKGETGLL 1175 Query: 895 -----PKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAV 949 P+G PG +G G G PG PGL G KG GD G +GP G+ G PGPPG PGA+ Sbjct: 1176 RAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGP--RGPTGIEGFPGPPGLPGAI 1233 Query: 950 I-NIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQG 1008 I G P R P PGS + G+KG+KGS G PG KG G G G Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVI----GIKGDKGSMGHPGPKGPPGTAGDMG 1289 Query: 1009 PPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMS-GPPGLPGNPGPAGQK 1067 PPG A L +G+ G +GF G KGEKG N FL S GPPG G GP G + Sbjct: 1290 PPGRLG--APGTPGLPGPRGDPGFQGFPGVKGEKG--NPGFLGSIGPPGPIGPKGPPGVR 1345 Query: 1068 GET----VVGPQGPPGAPGLPGPPGF-GRPGDPGPPG---------------PPGPPGPP 1107 G+ ++ G PG PG PG PG G PG PGPPG PG PGP Sbjct: 1346 GDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPA 1405 Query: 1108 AILG--AAVALPGPPGPPGQPGLPGSR 1132 G + PGP G G PGL G R Sbjct: 1406 GEKGNKGSKGEPGPAGSDGLPGLKGKR 1432 Score = 345 bits (885), Expect = 2e-94 Identities = 255/714 (35%), Positives = 304/714 (42%), Gaps = 153/714 (21%) Query: 503 PGDEEDLAAATTEEPLITAGGEESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAG 562 P EED+ +P + G P P G P P+ P + G G G Sbjct: 159 PAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFF--------GFPGAMG 210 Query: 563 PKGEKGDAGEELPGPPEP------SGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQL 616 P+G KG GE + G +GP GP +G +D+ GD Sbjct: 211 PRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGD------- 263 Query: 617 LRGPPGPPGPPGLPGIPGKP-GTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLP 675 +G G PGPPG G+PG+ G++ G PG PG G G+ G PG G GV G G P Sbjct: 264 -KGAMGEPGPPGPSGLPGESYGSE--KGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFP 320 Query: 676 GMKGEKGARGPNGSVGEKG------------DPGNRGLPGPPGKKGQAGPPGVMGPPGPP 723 G+ GE G +G G +G G + G+ G PGPPG +G GP G GPPG P Sbjct: 321 GLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVP 380 Query: 724 GPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGM--- 780 G PG PG G+ GLKG KG+RG G+ M Sbjct: 381 GSPGSSRPGLRGAPGWP-----------------------GLKGSKGERGRPGKDAMGTP 417 Query: 781 ------DGASIVGPPGPRGPPGHIKVLSNSL-INITHGFMNFSDIPELVGP--------- 824 + G PGP GPPG I + G++ IP + GP Sbjct: 418 GSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCT 477 Query: 825 -----PGPDGLPGLPGFPGPR---------------GPKGDTGLPGFPGLKGEQGE---K 861 PGP GLPGLPG G + G G+TGLPGFPG G QG+ K Sbjct: 478 QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK 537 Query: 862 GEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKG 921 GE G E + E +G G+PG+ G PG G G PG G GLPG G L+G KG Sbjct: 538 GEKG----ETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKG 593 Query: 922 TKGDPGVIMQGPPGLPGPPGPPGPPG----------AVINIKGAIFPI-PVRPHCKMPVD 970 +G PG G PG PGP GP GPPG + GA P P ++ V Sbjct: 594 DQGPPG--DPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVS 651 Query: 971 TAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGP-----------PGPPLDLAYL 1019 T PG P G G +G G+PGS G+ GD G GP PGPP Sbjct: 652 TPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPP------ 705 Query: 1020 RHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPG 1079 G GD+GF G KG G G PGLPG PG G KGE V G PG Sbjct: 706 --------GPKGDQGFPGTKGSLGCPG----KMGEPGLPGKPGLPGAKGEPAVAMPGGPG 753 Query: 1080 APGLPGPPG-FGRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSR 1132 PG PG G G G+ G PG PG PG P G L GP G PGQPG PG + Sbjct: 754 TPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEG----LDGPRGDPGQPGPPGEQ 803 Score = 343 bits (881), Expect = 5e-94 Identities = 278/783 (35%), Positives = 323/783 (41%), Gaps = 212/783 (27%) Query: 527 GSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEE------------- 573 G+ P GP P P R G G G KGE+G G++ Sbjct: 366 GARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGS 425 Query: 574 --LPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGS----GSGDLVGSEQLLRGP----PGP 623 LPG P P GP G + G +GS G G LL PGP Sbjct: 426 PGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGP 485 Query: 624 PGPPGLPG------IPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGV--------- 668 PG PGLPG IPG+ G G PGSPG G G PG PG +G PG+ Sbjct: 486 PGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQ 545 Query: 669 -DGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPG 727 +G G+PG G +G G G G G PG +GLPGP G+ +G G GPPG PG PG Sbjct: 546 PEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPG 605 Query: 728 PPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVG 787 PGP G +G EP L G G G+ GP+GE + + G Sbjct: 606 SPGPAGPAGPPGYGPQG--------EPGLQGTQGVPGAPGPPGEAGPRGELSVS-TPVPG 656 Query: 788 PPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGP------PGPDGLPGLPG--FPGP 839 PPGP GPPGH G IP +G PGPDG PG+PG FPGP Sbjct: 657 PPGPPGPPGH------------PGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGP 704 Query: 840 RGPKGDTGLPG---------------FPGLKGEQGEKGEPGAIL-----TEDIPLER--- 876 GPKGD G PG PG G G KGEP + T P ER Sbjct: 705 PGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNS 764 Query: 877 ----------LMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGR--------PGRPGLNG 918 L G G PG G GP G G PG GE G PGR G PGLNG Sbjct: 765 GEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNG 824 Query: 919 LKGT---------KGDPGVI---------MQGPPGLPGP---------------PGPPGP 945 LKG KGDPG+ G PG+PG PG GP Sbjct: 825 LKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGP 884 Query: 946 PG--AVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGD 1003 PG VI + G FP + P P +PG+P G+ G KG G PG+KGE+GD Sbjct: 885 PGEDGVIGMMG--FPGAIGP----PGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGD 938 Query: 1004 QGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGD--INGSFLMSGPPGLPGNP 1061 +G GP + + H + + KGE G KGF G GEKG+ + G + G GLPG Sbjct: 939 KGNPGP-------SEISHVIGD-KGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPA 990 Query: 1062 GPAGQKGETVVGPQGPPGAPGLPGPPGF----------------------GRPG------ 1093 GP G +G+ +G G PG PGL G PG GRPG Sbjct: 991 GPPGPRGD--LGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHG 1048 Query: 1094 --------------DPGPPGPPGPPGPPAILG--AAVALPGPPG------PPGQPGLPGS 1131 PGPPGP G PG P +G + PGPPG P G PG PGS Sbjct: 1049 LQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGS 1108 Query: 1132 RNL 1134 L Sbjct: 1109 PGL 1111 Score = 339 bits (870), Expect = 1e-92 Identities = 268/706 (37%), Positives = 311/706 (44%), Gaps = 153/706 (21%) Query: 527 GSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAG--------------- 571 G P DG P P R G+ G+ G KG+KGD G Sbjct: 297 GKPGKDGVP-----GFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQ 351 Query: 572 ----EELPGPPEPSG---PVGPTAGAEAEGS------GL----GWGSDVGS--------- 605 E PGPP P G P GP+ GS GL GW GS Sbjct: 352 EKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGK 411 Query: 606 ------GSGDLVGSEQLLRGPPGPPGPPG----LPGIPGKPGTDVFMGPPGSPGEDGPAG 655 GS GS L G PGPPGPPG G PG G ++G PG PG DGP G Sbjct: 412 DAMGTPGSPGCAGSPGL-PGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKG 470 Query: 656 EPGP--------PGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGK 707 EPG PGP G PG+ G G+ G+ G +GA G GS G PGN GLPG PG Sbjct: 471 EPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGS---PGSPGNTGLPGFPGF 527 Query: 708 KGQAGPPGVMGPPG----PPGPPGPPG-PGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAA 762 G G PG+ G G P G G PG PG G + +G T + L P Sbjct: 528 PGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKG--LPGPKGE 585 Query: 763 IGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELV 822 + L GEKGD+GP G+ G G+ GP GP GPPG+ G +P Sbjct: 586 LALSGEKGDQGPPGDPGSPGSP--GPAGPAGPPGYGP-------QGEPGLQGTQGVPGAP 636 Query: 823 GPPGPDGLPG-------LPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLE 875 GPPG G G +PG PGP GP G G G PG+ G G+ G+PG Sbjct: 637 GPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPG---------- 686 Query: 876 RLMGKKGEPGMHGA--PGPMGPKGP---PGHKGEFGLPGR---PGRPGLNGLKGTKGDPG 927 L G GEPG+ G PGP GPKG PG KG G PG+ PG PG GL G KG+P Sbjct: 687 -LPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPA 745 Query: 928 VIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKG 987 V M G PG PG PG G G I +P PG+P G +G Sbjct: 746 VAMPGGPGTPGFPGERGNSGEHGEIG-------------LPGLPGLPGTPGNEGLDGPRG 792 Query: 988 EKGSWGLPGSKGE-----KGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEK 1042 + G G PG +G +G +GAQG PG LN LKG+ G +G G KG+ Sbjct: 793 DPGQPGPPGEQGPPGRCIEGPRGAQGLPG-----------LNGLKGQQGRRGKTGPKGDP 841 Query: 1043 GDINGSFLMSGPPGLPGNPGPAGQKGET-VVGPQGPPGAPGLPGPPG----FGRPGDPGP 1097 G I G SG PG G+PG G +GE +G +G PG PG+ GPPG G G PG Sbjct: 842 G-IPG-LDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGA 899 Query: 1098 PGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNLVTAFSNMDD 1143 GPPGPPG P PG G PG PG+ G R A D Sbjct: 900 IGPPGPPGNPGT-------PGQRGSPGIPGVKGQRGTPGAKGEQGD 938 Score = 336 bits (861), Expect = 1e-91 Identities = 256/701 (36%), Positives = 302/701 (43%), Gaps = 145/701 (20%) Query: 548 TPAQREHVGMKGQAGPKGEKGDAGEE----LPGPPEPSGPVGPTAGAEAEGSGLGWGSDV 603 TP + G KG+ GEKGD G PG P P+GP GP GL V Sbjct: 573 TPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGV 632 Query: 604 GSGSGDL--------VGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAG 655 G + + GPPGPPGPPG PG G PG +G G PG GP G Sbjct: 633 PGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDG 692 Query: 656 EPG--------PPGPEG------------------QPGVDGATGLPGMKGEK-------- 681 EPG PPGP+G +PG+ G GLPG KGE Sbjct: 693 EPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP 752 Query: 682 ------GARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTM 735 G RG +G GE G PG GLPG PG +G GP G G PGPPG GPPG C Sbjct: 753 GTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGR-C-- 809 Query: 736 GLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPP 795 E G+ LN K G +G +G GPKG+ G+ G G PG G P Sbjct: 810 ---IEGPRGAQGLPGLNGLK--------GQQGRRGKTGPKGDPGIPGLDRSGFPGETGSP 858 Query: 796 GHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLK 855 G + + G + P ++GPPG DG+ G+ GFPG GP G G PG PG + Sbjct: 859 G---IPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQR 915 Query: 856 GEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPG 915 G G G G T G KGE G G PGP G KGE GL G G PG Sbjct: 916 GSPGIPGVKGQRGTP--------GAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPG 967 Query: 916 LNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPG 975 G +G G PG ++G GLPGP GPPGP G + + T +PG Sbjct: 968 EKGNRGVPGMPG--LKGLKGLPGPAGPPGPRGDLGS-------------------TGNPG 1006 Query: 976 SPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGE------ 1029 P L G+ G G+ G+PGSKG++G G G G P L + H L KGE Sbjct: 1007 EPGL---RGIPGSMGNMGMPGSKGKRGTLGFPGRAGRP-GLPGI-HGLQGDKGEPGYSEG 1061 Query: 1030 --------NGDKGFKGEKGEKGDIN--------------GSFLMSGPPGLPGNPGPAGQK 1067 GD G G+ G+KG++ G+ G PGLPG PGP G Sbjct: 1062 TRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDL 1121 Query: 1068 G----ETVVGP---QGPPGAPGLPGPPG-FGRPGDPGPPGPPGPPGPPAILGAAVALPGP 1119 G + ++GP +GPPG PG PG PG G GD G G PGP G G A PGP Sbjct: 1122 GFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGP 1181 Query: 1120 ------PGPPGQPGLPGSRNLVTAFSNMDDMLQKAHLVIEG 1154 G G G PG L M D + IEG Sbjct: 1182 RGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEG 1222 Score = 285 bits (728), Expect = 3e-76 Identities = 213/586 (36%), Positives = 261/586 (44%), Gaps = 113/586 (19%) Query: 527 GSPPPDGPPLPLPTVAPERWITPAQREHVGM---KGQAGPKGEKGDAGEE-LPGPPEPSG 582 G P GPP P P TP QR G+ KGQ G G KG+ G++ PGP E S Sbjct: 895 GFPGAIGPPGP-----PGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISH 949 Query: 583 PVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQL--LRGPPGPPGP---------PGLPG 631 +G +G G G + G + L L GP GPPGP PG PG Sbjct: 950 VIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG 1009 Query: 632 IPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGAR-----GP 686 + G PG+ MG G PG G G G PG G+PG+ G GL G KGE G GP Sbjct: 1010 LRGIPGS---MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGP 1066 Query: 687 NGSVGEKGDPGNRGL------PGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFE 740 G G+ G PG+ G PGPPG G AGP G G PG PG PG PGP LGF+ Sbjct: 1067 PGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGD--LGFK 1124 Query: 741 DTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKV 800 +G LL P + P G G G G +G++G DG I GP G +G G ++ Sbjct: 1125 GIKG-----LLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDG--IPGPAGEKGETGLLRA 1177 Query: 801 LSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGE 860 N P G G G PG PG PG +G GD G G G++G G Sbjct: 1178 PPGPRGN-----------PGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGP 1226 Query: 861 KGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMG-----------------PKGPPGHKG 903 G PGAI+ G +G PG G PGP G PKGPPG G Sbjct: 1227 PGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG 1286 Query: 904 EFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGL---------------PGPPGPPGPPGA 948 + G PGR G PG GL G +GDPG QG PG+ PGP GP GPPG Sbjct: 1287 DMGPPGRLGAPGTPGLPGPRGDPG--FQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGV 1344 Query: 949 --------VINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKG- 999 +I++ G+ P M + PG P + G +G+ G G PG+ G Sbjct: 1345 RGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGP 1404 Query: 1000 --EKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKG 1043 EKG++G++G PGP G +G G KG++G+ G Sbjct: 1405 AGEKGNKGSKGEPGP--------------AGSDGLPGLKGKRGDSG 1436 Score = 278 bits (710), Expect = 3e-74 Identities = 197/500 (39%), Positives = 237/500 (47%), Gaps = 63/500 (12%) Query: 663 EGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGP 722 +GQ DGA G KGEKG GP GS G+KG G GLPGP G KG G PG+ G G Sbjct: 36 KGQCFCDGAKG---EKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGV 92 Query: 723 PGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDG 782 G G PG SGS L P + P +G+ G G +G +G G+ G Sbjct: 93 RGISGLPG-------------FSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPG 139 Query: 783 ASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGP 842 +G PG G G +K + ++ P L G PGP GLPG PGFPGP GP Sbjct: 140 T--LGYPGIPGAAG-LKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP 196 Query: 843 KGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGP---- 898 G G GFPG G +G KG G ER++G KGE G+ G GP GP G Sbjct: 197 PGPPGFFGFPGAMGPRGPKGHMG---------ERVIGHKGERGVKGLTGPPGPPGTVIVT 247 Query: 899 ----------PGHKGEFGLPGRPGRPGLNGL--------KGTKGDPGVIMQGPPGLPGPP 940 G KG+ G G PG PG +GL KG GDPG +QG PG G P Sbjct: 248 LTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPG--LQGKPGKDGVP 305 Query: 941 GPPGPPGAVIN--IKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSK 998 G PG G N G + ++ G E + KG++G+ G PG + Sbjct: 306 GFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPR 365 Query: 999 GEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGD----INGSFLMSGP 1054 G +G QG GPPG P R L G G KG KGE+G G GS +G Sbjct: 366 GARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGS 425 Query: 1055 PGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPGFGRPGDPGPPGPPGPPGPPAILGAAV 1114 PGLPG+PGP G G+ +V +GPPG GLPG G PG PG GP G PG + Sbjct: 426 PGLPGSPGPPGPPGD-IVFRKGPPGDHGLPGY--LGSPGIPGVDGPKGEPG--LLCTQCP 480 Query: 1115 ALPGPPGPPGQPGLPGSRNL 1134 +PGPPG PG PGL G + + Sbjct: 481 YIPGPPGLPGLPGLHGVKGI 500 Score = 256 bits (655), Expect = 8e-68 Identities = 179/456 (39%), Positives = 204/456 (44%), Gaps = 97/456 (21%) Query: 556 GMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQ 615 G G G G+KG+ G+ PGPP GP GP + GS G G G + Sbjct: 1071 GDPGLPGDMGKKGEMGQ--PGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKG 1128 Query: 616 LLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPG-------PPGPEGQPGV 668 LL GPPG GPPGLPG PG PG G G G GPAGE G PPGP G PG Sbjct: 1129 LL-GPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGA 1187 Query: 669 DGATG---------LPGMKGEKGARGPNGSVGEKGDPGNRGLPGP--PGKKGQAGPPGVM 717 GA G LPG KG G GP G G +G PG GLPG PG+ G GPPG Sbjct: 1188 QGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSR 1247 Query: 718 GPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGE 777 G PG PGPPGPPG + IG+KG+KG G G Sbjct: 1248 GSPGAPGPPGPPG-----------------------------SHVIGIKGDKGSMGHPGP 1278 Query: 778 RGMDG-ASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGF 836 +G G A +GPPG G PG G PGP G PG GF Sbjct: 1279 KGPPGTAGDMGPPGRLGAPG------------------------TPGLPGPRGDPGFQGF 1314 Query: 837 PGPRGPKGDTGL------PGFPGLKGEQGEKGEPGAILTEDIP-LERLMGKKGEPGMHGA 889 PG +G KG+ G PG G KG G +G+PG + +P G GEPGM G Sbjct: 1315 PGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGE 1374 Query: 890 PGP------MGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVI-MQGPPGLPGPPGP 942 PGP +GP GP G G+ G PG PG G G KG+KG+PG G PGL G G Sbjct: 1375 PGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGD 1434 Query: 943 PGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPE 978 G P A +G +F + TA P PE Sbjct: 1435 SGSP-ATWTTRGFVF-------TRHSQTTAIPSCPE 1462 Score = 126 bits (317), Expect = 1e-28 Identities = 91/228 (39%), Positives = 105/228 (46%), Gaps = 35/228 (15%) Query: 523 GEESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGP--------KGEKGDAGEEL 574 G E PP P +P R P R G G GP KG+KG G Sbjct: 1219 GIEGFPGPPGLPGAIIPGQTGNRG-PPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPG 1277 Query: 575 P-GPPEPSGPVGPTAGAEAEGS-GL-GWGSDVG----------SGSGDLVGSEQLLRGPP 621 P GPP +G +GP A G+ GL G D G G+ +GS GPP Sbjct: 1278 PKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSI----GPP 1333 Query: 622 GPPGPPGLPGIPGKPGTDVFM------GPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLP 675 GP GP G PG+ G PGT + GPPG+PGE G GEPGPPGP G G G G P Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKP 1393 Query: 676 GMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPP 723 G G+ G GP GEKG+ G++G PGP G G G G G G P Sbjct: 1394 GKDGKPGTPGP---AGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438 Score = 84.3 bits (207), Expect = 7e-16 Identities = 60/162 (37%), Positives = 72/162 (44%), Gaps = 36/162 (22%) Query: 988 EKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDING 1047 +KG G+KGEKG++G GPPG P G KGF G +G G Sbjct: 35 DKGQCFCDGAKGEKGEKGFPGPPGSP-----------------GQKGFTGPEGLPGP--- 74 Query: 1048 SFLMSGPPGLPGNPGPAGQKG-ETVVGPQGPPGAPGLPGPPG----FGRPGDPGPPGPPG 1102 GP G PG PG G KG + G G G+PGLPG PG +G G PG G G Sbjct: 75 ----QGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKG 130 Query: 1103 PPGPPAILGAAVALPGPPGPPGQPGLPGSRNLVTAFSNMDDM 1144 G P LPG G PG PG G + A + +D+ Sbjct: 131 EQGFPG-------LPGTLGYPGIPGAAGLKGQKGAPAKEEDI 165 >gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo sapiens] Length = 1670 Score = 350 bits (897), Expect = 7e-96 Identities = 261/690 (37%), Positives = 291/690 (42%), Gaps = 174/690 (25%) Query: 558 KGQA---GPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSE 614 KGQ G KGEKG+ G PGPP G G T EG Sbjct: 36 KGQCFCDGAKGEKGEKG--FPGPPGSPGQKGFTG---PEG-------------------- 70 Query: 615 QLLRGPPGPPGPPGLP---------GIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQ 665 L GP GP G PGLP GI G PG G PG+PG GP G G PG G Sbjct: 71 --LPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGS 128 Query: 666 PGVDGATGLPGMKGEKGARGPNGSVGEKGDP-----------GNRGLPGPPGKKGQAGPP 714 G G GLPG G G G G G+KG P G+ GLPG PG +G GPP Sbjct: 129 KGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPP 188 Query: 715 GVMGPPGPPGPP---------GPPGPGCTMGLGFEDTEGSGSTQLLNEP---------KL 756 G GP GPPGPP GP GP MG +G + L P L Sbjct: 189 GFPGPVGPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTL 248 Query: 757 SRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGF-MNF 815 + P LKGEKGD+G GE GPPGP G PG ++G Sbjct: 249 TGPDNRTDLKGEKGDKGAMGE--------PGPPGPSGLPGE-----------SYGSEKGA 289 Query: 816 SDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPG----AILTED 871 P L G PG DG+PG PG G +G +G GL G G+KG++G+ G PG + Sbjct: 290 PGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDT 349 Query: 872 IPLERLMGKKGEPGMHGAPGPMGPKGPPGHKG-----EFGLPGRPGRPGLNGLKGTKGDP 926 + G G PG GA GP GP GPPG G GL G PG PGL G KG +G P Sbjct: 350 YQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRP 409 Query: 927 GVIMQ---------GPPGLPGPPGPPGPPGAVINIKG--------AIFPIPVRPH----- 964 G G PGLPG PGPPGPPG ++ KG P P Sbjct: 410 GKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPK 469 Query: 965 -------CKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLA 1017 + P PG P L HGVKG G G G KG G G G PG P Sbjct: 470 GEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFP---- 525 Query: 1018 YLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGP-------------- 1063 G GD G KGEKGE G + G PGL G PG Sbjct: 526 -------GFPGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKG 578 Query: 1064 -AGQKGETVV----GPQGPPGAPGLP---------GPPGFGRPGD---------PGPPGP 1100 G KGE + G QGPPG PG P GPPG+G G+ PG PGP Sbjct: 579 LPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGP 638 Query: 1101 PGPPGPPAILGAAVALPGPPGPPGQPGLPG 1130 PG GP L + +PGPPGPPG PG PG Sbjct: 639 PGEAGPRGELSVSTPVPGPPGPPGPPGHPG 668 Score = 349 bits (896), Expect = 9e-96 Identities = 266/703 (37%), Positives = 313/703 (44%), Gaps = 130/703 (18%) Query: 525 ESGSPPPDGPPLPLPTVAPERWITP-AQREHVGMKGQAGPKGEKGDAG-------EELPG 576 E G P P G P PE P + G+ G G KG +G +G LPG Sbjct: 50 EKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPG 109 Query: 577 PPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQLLRGPPGPPGPPGLPGIPGKP 636 P +GP G GS G G L G PG PG GL G G P Sbjct: 110 TPGNTGPYGLVGVPGCSGS---------KGEQGFPGLPGTL-GYPGIPGAAGLKGQKGAP 159 Query: 637 GTDVFM-----GPPGSPGEDGPAGEPGPPG---PEGQPGVDGATGLPGMKGEKGARGPNG 688 + + G PG PG GP G PGPPG P G PG G G PG G +G +G G Sbjct: 160 AKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHMG 219 Query: 689 S--VGEKGDPGNRGLPGPPGK-----------------KGQAGPPGVMGPPGPPGPPGPP 729 +G KG+ G +GL GPPG KG+ G G MG PGPPGP G P Sbjct: 220 ERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLP 279 Query: 730 GPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGAS----I 785 G G G L +P G +G KG+RG G G DG Sbjct: 280 GESYGSEKG-----APGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGD 334 Query: 786 VGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGD 845 +GPPG RGP + T G GP GP G PG+PG PG P G Sbjct: 335 IGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGAR---GPQGPSGPPGVPGSPGSSRP-GL 390 Query: 846 TGLPGFPGLKGEQGEKGEPG--AILTEDIPLERLMGKKGEPGMHGAPGPMGP-------K 896 G PG+PGLKG +GE+G PG A+ T P G G PG+ G+PGP GP K Sbjct: 391 RGAPGWPGLKGSKGERGRPGKDAMGTPGSP-----GCAGSPGLPGSPGPPGPPGDIVFRK 445 Query: 897 GPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAI 956 GPPG + GLPG G PG+ G+ G KG+PG++ P +PGPPG PG PG + +KG Sbjct: 446 GPPG---DHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPG-LHGVKG-- 499 Query: 957 FPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGD----QGAQGPPGP 1012 IP R + PGSP G G G+ G PG KGEKG+ +G G PG Sbjct: 500 --IPGRQGAAGLKGS--PGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGD 555 Query: 1013 P-LDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPG---LPGNPGPAGQKG 1068 P L R L+ + G G KG G KGE ++G GPPG PG+PGPAG G Sbjct: 556 PGLRGQPGRKGLDGIPGTPGVKGLPGPKGELA-LSGEKGDQGPPGDPGSPGSPGPAGPAG 614 Query: 1069 ETVVGPQGPPG------APGLPGPPGF--------------GRPGDPGPPGPPGPPGPPA 1108 GPQG PG PG PGPPG G PG PGPPG PGP GPP Sbjct: 615 PPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPG 674 Query: 1109 ILGA-------------------AVALPGPPGPPGQPGLPGSR 1132 I G+ + PGPPGP G G PG++ Sbjct: 675 IPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQGFPGTK 717 Score = 349 bits (895), Expect = 1e-95 Identities = 270/732 (36%), Positives = 314/732 (42%), Gaps = 154/732 (21%) Query: 527 GSPPPDGPP-LPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEELPGPPEPSGPVG 585 G P P GPP P P P P G G GP GE G G PGPP P G G Sbjct: 656 GPPGPPGPPGHPGPQGPPG---IPGSLGKCGDPGLPGPDGEPGIPGIGFPGPPGPKGDQG 712 Query: 586 PTAGAEAEGSGLGWGSDVGSGSGDLVGSEQ----LLRGPPGPPG---------------P 626 + G G G L G++ + G PG PG Sbjct: 713 FPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGL 772 Query: 627 PGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPGPPG-----PEGQPGVDGATGLPGMKGEK 681 PGLPG+PG PG + GP G PG+ GP GE GPPG P G G+ G GL G +G + Sbjct: 773 PGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRR 832 Query: 682 GARGPNGS-----------------------------VGEKGDPGNRGLPGPPGKKGQAG 712 G GP G +G++G PGN G+ GPPG+ G G Sbjct: 833 GKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIG 892 Query: 713 P---PGVMGPPGPPGPPGPPG----PGCTMGLGFEDTEGS-GSTQLLNEPKLSRPTAAIG 764 PG +GPPGPPG PG PG PG G T G+ G P S + IG Sbjct: 893 MMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISHVIG 952 Query: 765 LKGEKG------DRGPKGERGMDGA----SIVGPPGPRGPPGHIKVLSNSLINITHGFMN 814 KGE G + G KG RG+ G + G PGP GPPG L G Sbjct: 953 DKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDL---------GSTG 1003 Query: 815 FSDIPELVGPPGPDGLPGLPGFPGPRGP---KGDTGLPGFPGLKGEQGEKGEPGAIL--- 868 P L G PG G G+PG G RG G G PG PG+ G QG+KGEPG Sbjct: 1004 NPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTR 1063 Query: 869 ------TEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPG------L 916 T D L MGKKGE G G PG +GP GP G G G PG PG+PG Sbjct: 1064 PGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGF 1123 Query: 917 NGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGS 976 G+KG G PG+ +GPPGLPG PG PGP G + P P + + A PG Sbjct: 1124 KGIKGLLGPPGI--RGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGP 1181 Query: 977 PELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFK 1036 G KG++G+ G PG G KG G GP GP G +GF Sbjct: 1182 RGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGP-----------------TGIEGFP 1224 Query: 1037 GEKGEKGDI-NGSFLMSGPPGL---PGNPGPAGQKGETVVG------------PQGPPGA 1080 G G G I G GPPG PG PGP G G V+G P+GPPG Sbjct: 1225 GPPGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGT 1284 Query: 1081 PGLPGPPG-FGRPGDPGPPGPPGPPG------------PPAILGAAVALPGPPGPPGQP- 1126 G GPPG G PG PG PGP G PG P LG+ + PGP GP G P Sbjct: 1285 AGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGS-IGPPGPIGPKGPPG 1343 Query: 1127 --GLPGSRNLVT 1136 G PG+ +++ Sbjct: 1344 VRGDPGTLKIIS 1355 Score = 346 bits (888), Expect = 8e-95 Identities = 264/687 (38%), Positives = 306/687 (44%), Gaps = 144/687 (20%) Query: 556 GMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQ 615 G G G G +GD G+ PGPP GP G GL G L G +Q Sbjct: 780 GTPGNEGLDGPRGDPGQ--PGPPGEQGPPGRCIEGPRGAQGL-------PGLNGLKG-QQ 829 Query: 616 LLRGPPGPPGPPGLPGI-----------PGKPGTDVFMGP------PGSPGEDGPAGE-- 656 RG GP G PG+PG+ PG PG MGP PG+PG GP GE Sbjct: 830 GRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDG 889 Query: 657 -------------PGPPGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPG------ 697 PGPPG G PG G+ G+PG+KG++G G G G+KG+PG Sbjct: 890 VIGMMGFPGAIGPPGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISH 949 Query: 698 ---------------------NRGLPGPPGKKGQAGPPGVMGPPGPPGP------PGPPG 730 NRG+PG PG KG G PG GPPGP G PG PG Sbjct: 950 VIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG 1009 Query: 731 ----PGCTMGLGFEDTEGSGSTQLLNEP-KLSRPTAAIGLKGEKGDRGPKGERGMDGASI 785 PG +G ++G T L P + RP GL G G +G KGE G + Sbjct: 1010 LRGIPGSMGNMGMPGSKGKRGT--LGFPGRAGRP----GLPGIHGLQGDKGEPGYSEGTR 1063 Query: 786 VGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPG---FPGPRGP 842 GPPGP G PG + G M P +GP GP+G PG PG PG GP Sbjct: 1064 PGPPGPTGDPGLPGDMGKK------GEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGP 1117 Query: 843 KGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMG-------- 894 GD G G GL G G +G PG P MG +G+ G G PGP G Sbjct: 1118 HGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGP--MGIRGDQGRDGIPGPAGEKGETGLL 1175 Query: 895 -----PKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAV 949 P+G PG +G G G PG PGL G KG GD G +GP G+ G PGPPG PGA+ Sbjct: 1176 RAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGP--RGPTGIEGFPGPPGLPGAI 1233 Query: 950 I-NIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQG 1008 I G P R P PGS + G+KG+KGS G PG KG G G G Sbjct: 1234 IPGQTGNRGPPGSRGSPGAPGPPGPPGSHVI----GIKGDKGSMGHPGPKGPPGTAGDMG 1289 Query: 1009 PPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDINGSFLMS-GPPGLPGNPGPAGQK 1067 PPG A L +G+ G +GF G KGEKG N FL S GPPG G GP G + Sbjct: 1290 PPGRLG--APGTPGLPGPRGDPGFQGFPGVKGEKG--NPGFLGSIGPPGPIGPKGPPGVR 1345 Query: 1068 GET----VVGPQGPPGAPGLPGPPGF-GRPGDPGPPG---------------PPGPPGPP 1107 G+ ++ G PG PG PG PG G PG PGPPG PG PGP Sbjct: 1346 GDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGPA 1405 Query: 1108 AILG--AAVALPGPPGPPGQPGLPGSR 1132 G + PGP G G PGL G R Sbjct: 1406 GEKGNKGSKGEPGPAGSDGLPGLKGKR 1432 Score = 345 bits (885), Expect = 2e-94 Identities = 255/714 (35%), Positives = 304/714 (42%), Gaps = 153/714 (21%) Query: 503 PGDEEDLAAATTEEPLITAGGEESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAG 562 P EED+ +P + G P P G P P+ P + G G G Sbjct: 159 PAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFF--------GFPGAMG 210 Query: 563 PKGEKGDAGEELPGPPEP------SGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQL 616 P+G KG GE + G +GP GP +G +D+ GD Sbjct: 211 PRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLTGPDNRTDLKGEKGD------- 263 Query: 617 LRGPPGPPGPPGLPGIPGKP-GTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLP 675 +G G PGPPG G+PG+ G++ G PG PG G G+ G PG G GV G G P Sbjct: 264 -KGAMGEPGPPGPSGLPGESYGSE--KGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFP 320 Query: 676 GMKGEKGARGPNGSVGEKG------------DPGNRGLPGPPGKKGQAGPPGVMGPPGPP 723 G+ GE G +G G +G G + G+ G PGPPG +G GP G GPPG P Sbjct: 321 GLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVP 380 Query: 724 GPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGM--- 780 G PG PG G+ GLKG KG+RG G+ M Sbjct: 381 GSPGSSRPGLRGAPGWP-----------------------GLKGSKGERGRPGKDAMGTP 417 Query: 781 ------DGASIVGPPGPRGPPGHIKVLSNSL-INITHGFMNFSDIPELVGP--------- 824 + G PGP GPPG I + G++ IP + GP Sbjct: 418 GSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCT 477 Query: 825 -----PGPDGLPGLPGFPGPR---------------GPKGDTGLPGFPGLKGEQGE---K 861 PGP GLPGLPG G + G G+TGLPGFPG G QG+ K Sbjct: 478 QCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLK 537 Query: 862 GEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPGLNGLKG 921 GE G E + E +G G+PG+ G PG G G PG G GLPG G L+G KG Sbjct: 538 GEKG----ETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKG 593 Query: 922 TKGDPGVIMQGPPGLPGPPGPPGPPG----------AVINIKGAIFPI-PVRPHCKMPVD 970 +G PG G PG PGP GP GPPG + GA P P ++ V Sbjct: 594 DQGPPG--DPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVS 651 Query: 971 TAHPGSPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGP-----------PGPPLDLAYL 1019 T PG P G G +G G+PGS G+ GD G GP PGPP Sbjct: 652 TPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGPP------ 705 Query: 1020 RHFLNNLKGENGDKGFKGEKGEKGDINGSFLMSGPPGLPGNPGPAGQKGETVVGPQGPPG 1079 G GD+GF G KG G G PGLPG PG G KGE V G PG Sbjct: 706 --------GPKGDQGFPGTKGSLGCPG----KMGEPGLPGKPGLPGAKGEPAVAMPGGPG 753 Query: 1080 APGLPGPPG-FGRPGDPGPPGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSR 1132 PG PG G G G+ G PG PG PG P G L GP G PGQPG PG + Sbjct: 754 TPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEG----LDGPRGDPGQPGPPGEQ 803 Score = 343 bits (881), Expect = 5e-94 Identities = 278/783 (35%), Positives = 323/783 (41%), Gaps = 212/783 (27%) Query: 527 GSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAGEE------------- 573 G+ P GP P P R G G G KGE+G G++ Sbjct: 366 GARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGS 425 Query: 574 --LPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGS----GSGDLVGSEQLLRGP----PGP 623 LPG P P GP G + G +GS G G LL PGP Sbjct: 426 PGLPGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGP 485 Query: 624 PGPPGLPG------IPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGV--------- 668 PG PGLPG IPG+ G G PGSPG G G PG PG +G PG+ Sbjct: 486 PGLPGLPGLHGVKGIPGRQGAAGLKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQ 545 Query: 669 -DGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPG 727 +G G+PG G +G G G G G PG +GLPGP G+ +G G GPPG PG PG Sbjct: 546 PEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPG 605 Query: 728 PPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVG 787 PGP G +G EP L G G G+ GP+GE + + G Sbjct: 606 SPGPAGPAGPPGYGPQG--------EPGLQGTQGVPGAPGPPGEAGPRGELSVS-TPVPG 656 Query: 788 PPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGP------PGPDGLPGLPG--FPGP 839 PPGP GPPGH G IP +G PGPDG PG+PG FPGP Sbjct: 657 PPGPPGPPGH------------PGPQGPPGIPGSLGKCGDPGLPGPDGEPGIPGIGFPGP 704 Query: 840 RGPKGDTGLPG---------------FPGLKGEQGEKGEPGAIL-----TEDIPLER--- 876 GPKGD G PG PG G G KGEP + T P ER Sbjct: 705 PGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGPGTPGFPGERGNS 764 Query: 877 ----------LMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGR--------PGRPGLNG 918 L G G PG G GP G G PG GE G PGR G PGLNG Sbjct: 765 GEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGRCIEGPRGAQGLPGLNG 824 Query: 919 LKGT---------KGDPGVI---------MQGPPGLPGP---------------PGPPGP 945 LKG KGDPG+ G PG+PG PG GP Sbjct: 825 LKGQQGRRGKTGPKGDPGIPGLDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGP 884 Query: 946 PG--AVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKGEKGD 1003 PG VI + G FP + P P +PG+P G+ G KG G PG+KGE+GD Sbjct: 885 PGEDGVIGMMG--FPGAIGP----PGPPGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGD 938 Query: 1004 QGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGD--INGSFLMSGPPGLPGNP 1061 +G GP + + H + + KGE G KGF G GEKG+ + G + G GLPG Sbjct: 939 KGNPGP-------SEISHVIGD-KGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPA 990 Query: 1062 GPAGQKGETVVGPQGPPGAPGLPGPPGF----------------------GRPG------ 1093 GP G +G+ +G G PG PGL G PG GRPG Sbjct: 991 GPPGPRGD--LGSTGNPGEPGLRGIPGSMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHG 1048 Query: 1094 --------------DPGPPGPPGPPGPPAILG--AAVALPGPPG------PPGQPGLPGS 1131 PGPPGP G PG P +G + PGPPG P G PG PGS Sbjct: 1049 LQGDKGEPGYSEGTRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGS 1108 Query: 1132 RNL 1134 L Sbjct: 1109 PGL 1111 Score = 339 bits (870), Expect = 1e-92 Identities = 268/706 (37%), Positives = 311/706 (44%), Gaps = 153/706 (21%) Query: 527 GSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGPKGEKGDAG--------------- 571 G P DG P P R G+ G+ G KG+KGD G Sbjct: 297 GKPGKDGVP-----GFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQ 351 Query: 572 ----EELPGPPEPSG---PVGPTAGAEAEGS------GL----GWGSDVGS--------- 605 E PGPP P G P GP+ GS GL GW GS Sbjct: 352 EKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGK 411 Query: 606 ------GSGDLVGSEQLLRGPPGPPGPPG----LPGIPGKPGTDVFMGPPGSPGEDGPAG 655 GS GS L G PGPPGPPG G PG G ++G PG PG DGP G Sbjct: 412 DAMGTPGSPGCAGSPGL-PGSPGPPGPPGDIVFRKGPPGDHGLPGYLGSPGIPGVDGPKG 470 Query: 656 EPGP--------PGPEGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGK 707 EPG PGP G PG+ G G+ G+ G +GA G GS G PGN GLPG PG Sbjct: 471 EPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAGLKGS---PGSPGNTGLPGFPGF 527 Query: 708 KGQAGPPGVMGPPG----PPGPPGPPG-PGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAA 762 G G PG+ G G P G G PG PG G + +G T + L P Sbjct: 528 PGAQGDPGLKGEKGETLQPEGQVGVPGDPGLRGQPGRKGLDGIPGTPGVKG--LPGPKGE 585 Query: 763 IGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELV 822 + L GEKGD+GP G+ G G+ GP GP GPPG+ G +P Sbjct: 586 LALSGEKGDQGPPGDPGSPGSP--GPAGPAGPPGYGP-------QGEPGLQGTQGVPGAP 636 Query: 823 GPPGPDGLPG-------LPGFPGPRGPKGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLE 875 GPPG G G +PG PGP GP G G G PG+ G G+ G+PG Sbjct: 637 GPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPG---------- 686 Query: 876 RLMGKKGEPGMHGA--PGPMGPKGP---PGHKGEFGLPGR---PGRPGLNGLKGTKGDPG 927 L G GEPG+ G PGP GPKG PG KG G PG+ PG PG GL G KG+P Sbjct: 687 -LPGPDGEPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPA 745 Query: 928 VIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKG 987 V M G PG PG PG G G I +P PG+P G +G Sbjct: 746 VAMPGGPGTPGFPGERGNSGEHGEIG-------------LPGLPGLPGTPGNEGLDGPRG 792 Query: 988 EKGSWGLPGSKGE-----KGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEK 1042 + G G PG +G +G +GAQG PG LN LKG+ G +G G KG+ Sbjct: 793 DPGQPGPPGEQGPPGRCIEGPRGAQGLPG-----------LNGLKGQQGRRGKTGPKGDP 841 Query: 1043 GDINGSFLMSGPPGLPGNPGPAGQKGET-VVGPQGPPGAPGLPGPPG----FGRPGDPGP 1097 G I G SG PG G+PG G +GE +G +G PG PG+ GPPG G G PG Sbjct: 842 G-IPG-LDRSGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGA 899 Query: 1098 PGPPGPPGPPAILGAAVALPGPPGPPGQPGLPGSRNLVTAFSNMDD 1143 GPPGPPG P PG G PG PG+ G R A D Sbjct: 900 IGPPGPPGNPGT-------PGQRGSPGIPGVKGQRGTPGAKGEQGD 938 Score = 336 bits (861), Expect = 1e-91 Identities = 256/701 (36%), Positives = 302/701 (43%), Gaps = 145/701 (20%) Query: 548 TPAQREHVGMKGQAGPKGEKGDAGEE----LPGPPEPSGPVGPTAGAEAEGSGLGWGSDV 603 TP + G KG+ GEKGD G PG P P+GP GP GL V Sbjct: 573 TPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGPQGEPGLQGTQGV 632 Query: 604 GSGSGDL--------VGSEQLLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAG 655 G + + GPPGPPGPPG PG G PG +G G PG GP G Sbjct: 633 PGAPGPPGEAGPRGELSVSTPVPGPPGPPGPPGHPGPQGPPGIPGSLGKCGDPGLPGPDG 692 Query: 656 EPG--------PPGPEG------------------QPGVDGATGLPGMKGEK-------- 681 EPG PPGP+G +PG+ G GLPG KGE Sbjct: 693 EPGIPGIGFPGPPGPKGDQGFPGTKGSLGCPGKMGEPGLPGKPGLPGAKGEPAVAMPGGP 752 Query: 682 ------GARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTM 735 G RG +G GE G PG GLPG PG +G GP G G PGPPG GPPG C Sbjct: 753 GTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGPPGEQGPPGR-C-- 809 Query: 736 GLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPP 795 E G+ LN K G +G +G GPKG+ G+ G G PG G P Sbjct: 810 ---IEGPRGAQGLPGLNGLK--------GQQGRRGKTGPKGDPGIPGLDRSGFPGETGSP 858 Query: 796 GHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLK 855 G + + G + P ++GPPG DG+ G+ GFPG GP G G PG PG + Sbjct: 859 G---IPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQR 915 Query: 856 GEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGPPGHKGEFGLPGRPGRPG 915 G G G G T G KGE G G PGP G KGE GL G G PG Sbjct: 916 GSPGIPGVKGQRGTP--------GAKGEQGDKGNPGPSEISHVIGDKGEPGLKGFAGNPG 967 Query: 916 LNGLKGTKGDPGVIMQGPPGLPGPPGPPGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPG 975 G +G G PG ++G GLPGP GPPGP G + + T +PG Sbjct: 968 EKGNRGVPGMPG--LKGLKGLPGPAGPPGPRGDLGS-------------------TGNPG 1006 Query: 976 SPELITFHGVKGEKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGE------ 1029 P L G+ G G+ G+PGSKG++G G G G P L + H L KGE Sbjct: 1007 EPGL---RGIPGSMGNMGMPGSKGKRGTLGFPGRAGRP-GLPGI-HGLQGDKGEPGYSEG 1061 Query: 1030 --------NGDKGFKGEKGEKGDIN--------------GSFLMSGPPGLPGNPGPAGQK 1067 GD G G+ G+KG++ G+ G PGLPG PGP G Sbjct: 1062 TRPGPPGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDL 1121 Query: 1068 G----ETVVGP---QGPPGAPGLPGPPG-FGRPGDPGPPGPPGPPGPPAILGAAVALPGP 1119 G + ++GP +GPPG PG PG PG G GD G G PGP G G A PGP Sbjct: 1122 GFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGP 1181 Query: 1120 ------PGPPGQPGLPGSRNLVTAFSNMDDMLQKAHLVIEG 1154 G G G PG L M D + IEG Sbjct: 1182 RGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEG 1222 Score = 285 bits (728), Expect = 3e-76 Identities = 213/586 (36%), Positives = 261/586 (44%), Gaps = 113/586 (19%) Query: 527 GSPPPDGPPLPLPTVAPERWITPAQREHVGM---KGQAGPKGEKGDAGEE-LPGPPEPSG 582 G P GPP P P TP QR G+ KGQ G G KG+ G++ PGP E S Sbjct: 895 GFPGAIGPPGP-----PGNPGTPGQRGSPGIPGVKGQRGTPGAKGEQGDKGNPGPSEISH 949 Query: 583 PVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQL--LRGPPGPPGP---------PGLPG 631 +G +G G G + G + L L GP GPPGP PG PG Sbjct: 950 VIGDKGEPGLKGFAGNPGEKGNRGVPGMPGLKGLKGLPGPAGPPGPRGDLGSTGNPGEPG 1009 Query: 632 IPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLPGMKGEKGAR-----GP 686 + G PG+ MG G PG G G G PG G+PG+ G GL G KGE G GP Sbjct: 1010 LRGIPGS---MGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGP 1066 Query: 687 NGSVGEKGDPGNRGL------PGPPGKKGQAGPPGVMGPPGPPGPPGPPGPGCTMGLGFE 740 G G+ G PG+ G PGPPG G AGP G G PG PG PG PGP LGF+ Sbjct: 1067 PGPTGDPGLPGDMGKKGEMGQPGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGD--LGFK 1124 Query: 741 DTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDGASIVGPPGPRGPPGHIKV 800 +G LL P + P G G G G +G++G DG I GP G +G G ++ Sbjct: 1125 GIKG-----LLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDG--IPGPAGEKGETGLLRA 1177 Query: 801 LSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGPKGDTGLPGFPGLKGEQGE 860 N P G G G PG PG PG +G GD G G G++G G Sbjct: 1178 PPGPRGN-----------PGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGP 1226 Query: 861 KGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMG-----------------PKGPPGHKG 903 G PGAI+ G +G PG G PGP G PKGPPG G Sbjct: 1227 PGLPGAIIPGQTGNRGPPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPGPKGPPGTAG 1286 Query: 904 EFGLPGRPGRPGLNGLKGTKGDPGVIMQGPPGL---------------PGPPGPPGPPGA 948 + G PGR G PG GL G +GDPG QG PG+ PGP GP GPPG Sbjct: 1287 DMGPPGRLGAPGTPGLPGPRGDPG--FQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGV 1344 Query: 949 --------VINIKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSKG- 999 +I++ G+ P M + PG P + G +G+ G G PG+ G Sbjct: 1345 RGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDGKPGTPGP 1404 Query: 1000 --EKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKG 1043 EKG++G++G PGP G +G G KG++G+ G Sbjct: 1405 AGEKGNKGSKGEPGP--------------AGSDGLPGLKGKRGDSG 1436 Score = 278 bits (710), Expect = 3e-74 Identities = 197/500 (39%), Positives = 237/500 (47%), Gaps = 63/500 (12%) Query: 663 EGQPGVDGATGLPGMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGP 722 +GQ DGA G KGEKG GP GS G+KG G GLPGP G KG G PG+ G G Sbjct: 36 KGQCFCDGAKG---EKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPGLPGLTGSKGV 92 Query: 723 PGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGERGMDG 782 G G PG SGS L P + P +G+ G G +G +G G+ G Sbjct: 93 RGISGLPG-------------FSGSPGLPGTPGNTGPYGLVGVPGCSGSKGEQGFPGLPG 139 Query: 783 ASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGFPGPRGP 842 +G PG G G +K + ++ P L G PGP GLPG PGFPGP GP Sbjct: 140 T--LGYPGIPGAAG-LKGQKGAPAKEEDIELDAKGDPGLPGAPGPQGLPGPPGFPGPVGP 196 Query: 843 KGDTGLPGFPGLKGEQGEKGEPGAILTEDIPLERLMGKKGEPGMHGAPGPMGPKGP---- 898 G G GFPG G +G KG G ER++G KGE G+ G GP GP G Sbjct: 197 PGPPGFFGFPGAMGPRGPKGHMG---------ERVIGHKGERGVKGLTGPPGPPGTVIVT 247 Query: 899 ----------PGHKGEFGLPGRPGRPGLNGL--------KGTKGDPGVIMQGPPGLPGPP 940 G KG+ G G PG PG +GL KG GDPG +QG PG G P Sbjct: 248 LTGPDNRTDLKGEKGDKGAMGEPGPPGPSGLPGESYGSEKGAPGDPG--LQGKPGKDGVP 305 Query: 941 GPPGPPGAVIN--IKGAIFPIPVRPHCKMPVDTAHPGSPELITFHGVKGEKGSWGLPGSK 998 G PG G N G + ++ G E + KG++G+ G PG + Sbjct: 306 GFPGSEGVKGNRGFPGLMGEDGIKGQKGDIGPPGFRGPTEYYDTYQEKGDEGTPGPPGPR 365 Query: 999 GEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGD----INGSFLMSGP 1054 G +G QG GPPG P R L G G KG KGE+G G GS +G Sbjct: 366 GARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMGTPGSPGCAGS 425 Query: 1055 PGLPGNPGPAGQKGETVVGPQGPPGAPGLPGPPGFGRPGDPGPPGPPGPPGPPAILGAAV 1114 PGLPG+PGP G G+ +V +GPPG GLPG G PG PG GP G PG + Sbjct: 426 PGLPGSPGPPGPPGD-IVFRKGPPGDHGLPGY--LGSPGIPGVDGPKGEPG--LLCTQCP 480 Query: 1115 ALPGPPGPPGQPGLPGSRNL 1134 +PGPPG PG PGL G + + Sbjct: 481 YIPGPPGLPGLPGLHGVKGI 500 Score = 256 bits (655), Expect = 8e-68 Identities = 179/456 (39%), Positives = 204/456 (44%), Gaps = 97/456 (21%) Query: 556 GMKGQAGPKGEKGDAGEELPGPPEPSGPVGPTAGAEAEGSGLGWGSDVGSGSGDLVGSEQ 615 G G G G+KG+ G+ PGPP GP GP + GS G G G + Sbjct: 1071 GDPGLPGDMGKKGEMGQ--PGPPGHLGPAGPEGAPGSPGSPGLPGKPGPHGDLGFKGIKG 1128 Query: 616 LLRGPPGPPGPPGLPGIPGKPGTDVFMGPPGSPGEDGPAGEPG-------PPGPEGQPGV 668 LL GPPG GPPGLPG PG PG G G G GPAGE G PPGP G PG Sbjct: 1129 LL-GPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGA 1187 Query: 669 DGATG---------LPGMKGEKGARGPNGSVGEKGDPGNRGLPGP--PGKKGQAGPPGVM 717 GA G LPG KG G GP G G +G PG GLPG PG+ G GPPG Sbjct: 1188 QGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSR 1247 Query: 718 GPPGPPGPPGPPGPGCTMGLGFEDTEGSGSTQLLNEPKLSRPTAAIGLKGEKGDRGPKGE 777 G PG PGPPGPPG + IG+KG+KG G G Sbjct: 1248 GSPGAPGPPGPPG-----------------------------SHVIGIKGDKGSMGHPGP 1278 Query: 778 RGMDG-ASIVGPPGPRGPPGHIKVLSNSLINITHGFMNFSDIPELVGPPGPDGLPGLPGF 836 +G G A +GPPG G PG G PGP G PG GF Sbjct: 1279 KGPPGTAGDMGPPGRLGAPG------------------------TPGLPGPRGDPGFQGF 1314 Query: 837 PGPRGPKGDTGL------PGFPGLKGEQGEKGEPGAILTEDIP-LERLMGKKGEPGMHGA 889 PG +G KG+ G PG G KG G +G+PG + +P G GEPGM G Sbjct: 1315 PGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGE 1374 Query: 890 PGP------MGPKGPPGHKGEFGLPGRPGRPGLNGLKGTKGDPGVI-MQGPPGLPGPPGP 942 PGP +GP GP G G+ G PG PG G G KG+KG+PG G PGL G G Sbjct: 1375 PGPPGPPGNLGPCGPRGKPGKDGKPGTPGPAGEKGNKGSKGEPGPAGSDGLPGLKGKRGD 1434 Query: 943 PGPPGAVINIKGAIFPIPVRPHCKMPVDTAHPGSPE 978 G P A +G +F + TA P PE Sbjct: 1435 SGSP-ATWTTRGFVF-------TRHSQTTAIPSCPE 1462 Score = 126 bits (317), Expect = 1e-28 Identities = 91/228 (39%), Positives = 105/228 (46%), Gaps = 35/228 (15%) Query: 523 GEESGSPPPDGPPLPLPTVAPERWITPAQREHVGMKGQAGP--------KGEKGDAGEEL 574 G E PP P +P R P R G G GP KG+KG G Sbjct: 1219 GIEGFPGPPGLPGAIIPGQTGNRG-PPGSRGSPGAPGPPGPPGSHVIGIKGDKGSMGHPG 1277 Query: 575 P-GPPEPSGPVGPTAGAEAEGS-GL-GWGSDVG----------SGSGDLVGSEQLLRGPP 621 P GPP +G +GP A G+ GL G D G G+ +GS GPP Sbjct: 1278 PKGPPGTAGDMGPPGRLGAPGTPGLPGPRGDPGFQGFPGVKGEKGNPGFLGSI----GPP 1333 Query: 622 GPPGPPGLPGIPGKPGTDVFM------GPPGSPGEDGPAGEPGPPGPEGQPGVDGATGLP 675 GP GP G PG+ G PGT + GPPG+PGE G GEPGPPGP G G G G P Sbjct: 1334 GPIGPKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKP 1393 Query: 676 GMKGEKGARGPNGSVGEKGDPGNRGLPGPPGKKGQAGPPGVMGPPGPP 723 G G+ G GP GEKG+ G++G PGP G G G G G G P Sbjct: 1394 GKDGKPGTPGP---AGEKGNKGSKGEPGPAGSDGLPGLKGKRGDSGSP 1438 Score = 84.3 bits (207), Expect = 7e-16 Identities = 60/162 (37%), Positives = 72/162 (44%), Gaps = 36/162 (22%) Query: 988 EKGSWGLPGSKGEKGDQGAQGPPGPPLDLAYLRHFLNNLKGENGDKGFKGEKGEKGDING 1047 +KG G+KGEKG++G GPPG P G KGF G +G G Sbjct: 35 DKGQCFCDGAKGEKGEKGFPGPPGSP-----------------GQKGFTGPEGLPGP--- 74 Query: 1048 SFLMSGPPGLPGNPGPAGQKG-ETVVGPQGPPGAPGLPGPPG----FGRPGDPGPPGPPG 1102 GP G PG PG G KG + G G G+PGLPG PG +G G PG G G Sbjct: 75 ----QGPKGFPGLPGLTGSKGVRGISGLPGFSGSPGLPGTPGNTGPYGLVGVPGCSGSKG 130 Query: 1103 PPGPPAILGAAVALPGPPGPPGQPGLPGSRNLVTAFSNMDDM 1144 G P LPG G PG PG G + A + +D+ Sbjct: 131 EQGFPG-------LPGTLGYPGIPGAAGLKGQKGAPAKEEDI 165 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.137 0.421 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 86,212,378 Number of Sequences: 37866 Number of extensions: 6919043 Number of successful extensions: 245542 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 656 Number of HSP's successfully gapped in prelim test: 1695 Number of HSP's that attempted gapping in prelim test: 29282 Number of HSP's gapped (non-prelim): 31989 length of query: 1388 length of database: 18,247,518 effective HSP length: 115 effective length of query: 1273 effective length of database: 13,892,928 effective search space: 17685697344 effective search space used: 17685697344 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.