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Search of human proteins with 223890197
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223890197 mouse double minute 2 homolog isoform MDM2f [Homo
sapiens]
(452 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223890197 mouse double minute 2 homolog isoform MDM2f [Homo s... 914 0.0
gi|89993689 mouse double minute 2 homolog isoform MDM2 [Homo sap... 892 0.0
gi|223890201 mouse double minute 2 homolog isoform MDM2g [Homo s... 758 0.0
gi|223890205 mouse double minute 2 homolog isoform MDM2h [Homo s... 577 e-164
gi|223890207 mouse double minute 2 homolog isoform MDM2i [Homo s... 496 e-140
gi|89993690 mouse double minute 2 homolog isoform MDM2a [Homo sa... 237 2e-62
gi|89993693 mouse double minute 2 homolog isoform MDM2d [Homo sa... 193 2e-49
gi|89993691 mouse double minute 2 homolog isoform MDM2e [Homo sa... 175 7e-44
gi|88702791 mouse double minute 4 homolog [Homo sapiens] 165 7e-41
gi|89993692 mouse double minute 2 homolog isoform MDM2b [Homo sa... 117 2e-26
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 60 5e-09
gi|190194423 SPARC-like 1 [Homo sapiens] 46 6e-05
gi|190341024 SPARC-like 1 [Homo sapiens] 46 6e-05
gi|88759348 ring finger protein 219 [Homo sapiens] 43 5e-04
gi|223278368 neuralized-like [Homo sapiens] 42 0.001
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 42 0.001
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 42 0.001
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 42 0.001
gi|33946285 baculoviral IAP repeat-containing protein 3 [Homo sa... 41 0.003
gi|4502139 baculoviral IAP repeat-containing protein 3 [Homo sap... 41 0.003
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 40 0.003
gi|16445033 ACRC protein [Homo sapiens] 40 0.006
gi|124517695 ankyrin repeat domain 36B [Homo sapiens] 40 0.006
gi|217416388 neuralized homolog 1B [Homo sapiens] 39 0.007
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 39 0.007
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 39 0.007
gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens] 39 0.007
gi|58743365 ring finger protein 157 [Homo sapiens] 39 0.007
gi|38788243 myosin regulatory light chain interacting protein [H... 39 0.007
gi|39780588 TSR1, 20S rRNA accumulation [Homo sapiens] 39 0.007
>gi|223890197 mouse double minute 2 homolog isoform MDM2f [Homo
sapiens]
Length = 452
Score = 914 bits (2362), Expect = 0.0
Identities = 452/452 (100%), Positives = 452/452 (100%)
Query: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEKI 60
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEKI
Sbjct: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEKI 60
Query: 61 YTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTS 120
YTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTS
Sbjct: 61 YTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTS 120
Query: 121 SRRRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTP 180
SRRRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTP
Sbjct: 121 SRRRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTP 180
Query: 181 SNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVT 240
SNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVT
Sbjct: 181 SNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVT 240
Query: 241 VYQAGESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKG 300
VYQAGESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKG
Sbjct: 241 VYQAGESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKG 300
Query: 301 EISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPST 360
EISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPST
Sbjct: 301 EISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPST 360
Query: 361 SSSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLM 420
SSSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLM
Sbjct: 361 SSSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLM 420
Query: 421 ACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP 452
ACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP
Sbjct: 421 ACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP 452
>gi|89993689 mouse double minute 2 homolog isoform MDM2 [Homo
sapiens]
Length = 497
Score = 892 bits (2306), Expect = 0.0
Identities = 452/497 (90%), Positives = 452/497 (90%), Gaps = 45/497 (9%)
Query: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKE-- 58
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKE
Sbjct: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
Query: 59 -------------------------------------------KIYTMIYRNLVVVNQQE 75
KIYTMIYRNLVVVNQQE
Sbjct: 61 FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE 120
Query: 76 SSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDE 135
SSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDE
Sbjct: 121 SSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDE 180
Query: 136 LSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGD 195
LSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGD
Sbjct: 181 LSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGD 240
Query: 196 WLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEED 255
WLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEED
Sbjct: 241 WLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEED 300
Query: 256 PEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAE 315
PEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAE
Sbjct: 301 PEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAE 360
Query: 316 EGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEF 375
EGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEF
Sbjct: 361 EGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEF 420
Query: 376 EREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKP 435
EREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKP
Sbjct: 421 EREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKP 480
Query: 436 CPVCRQPIQMIVLTYFP 452
CPVCRQPIQMIVLTYFP
Sbjct: 481 CPVCRQPIQMIVLTYFP 497
>gi|223890201 mouse double minute 2 homolog isoform MDM2g [Homo
sapiens]
Length = 444
Score = 758 bits (1958), Expect = 0.0
Identities = 396/491 (80%), Positives = 396/491 (80%), Gaps = 92/491 (18%)
Query: 7 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKE-------- 58
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKE
Sbjct: 1 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVLFYLGQY 60
Query: 59 -------------------------------------KIYTMIYRNLVVVNQQESSDSGT 81
KIYTMIYRNLVVVNQQESSDSGT
Sbjct: 61 IMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQESSDSGT 120
Query: 82 SVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQ 141
SVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQ
Sbjct: 121 SVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQ 180
Query: 142 RKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDS 201
RKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNP
Sbjct: 181 RKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNP------------------ 222
Query: 202 VSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEEDPEISLA 261
D D VYQVTVYQAGESDTDSFEEDPEISLA
Sbjct: 223 -----------------------------DLDAGVYQVTVYQAGESDTDSFEEDPEISLA 253
Query: 262 DYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVP 321
DYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVP
Sbjct: 254 DYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVP 313
Query: 322 DCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQ 381
DCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQ
Sbjct: 314 DCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQ 373
Query: 382 DKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQ 441
DKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQ
Sbjct: 374 DKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQ 433
Query: 442 PIQMIVLTYFP 452
PIQMIVLTYFP
Sbjct: 434 PIQMIVLTYFP 444
>gi|223890205 mouse double minute 2 homolog isoform MDM2h [Homo
sapiens]
Length = 442
Score = 577 bits (1486), Expect = e-164
Identities = 323/506 (63%), Positives = 339/506 (66%), Gaps = 118/506 (23%)
Query: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKE-- 58
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKE
Sbjct: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
Query: 59 -------------------------------------------KIYTMIYRNLVVVNQQE 75
KIYTMIYRNLVVVNQQE
Sbjct: 61 FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE 120
Query: 76 SSDSGTSVSENRCHLEGGSDQKD--------LVQELQEEKPSSSHLVSRPSTSSRRRAIS 127
+ S R + S +++E+ E+ SSS PS +S
Sbjct: 121 ENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVS 180
Query: 128 ETEENSDELSGERQRKRHKSDSISLSFD-ESLALCVIREICCERSSSSESTGTPSNPDLD 186
E SG+ + SD S+ F+ ESL
Sbjct: 181 EH-------SGDWLDQDSVSDQFSVEFEVESLD--------------------------- 206
Query: 187 AGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGE 246
S+ +S+ E + L SDEDDEVYQVTVYQAGE
Sbjct: 207 ----------------SEDYSLSEEGQEL--------------SDEDDEVYQVTVYQAGE 236
Query: 247 SDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKA 306
SDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKA
Sbjct: 237 SDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKA 296
Query: 307 KLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIY 366
KLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIY
Sbjct: 297 KLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIY 356
Query: 367 SSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCA 426
SSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCA
Sbjct: 357 SSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCA 416
Query: 427 KKLKKRNKPCPVCRQPIQMIVLTYFP 452
KKLKKRNKPCPVCRQPIQMIVLTYFP
Sbjct: 417 KKLKKRNKPCPVCRQPIQMIVLTYFP 442
>gi|223890207 mouse double minute 2 homolog isoform MDM2i [Homo
sapiens]
Length = 295
Score = 496 bits (1276), Expect = e-140
Identities = 243/269 (90%), Positives = 243/269 (90%), Gaps = 26/269 (9%)
Query: 184 DLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQ 243
DLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDE
Sbjct: 53 DLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDE-------- 104
Query: 244 AGESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEIS 303
DYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEIS
Sbjct: 105 ------------------DYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEIS 146
Query: 304 EKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSS 363
EKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSS
Sbjct: 147 EKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSS 206
Query: 364 IIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACF 423
IIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACF
Sbjct: 207 IIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACF 266
Query: 424 TCAKKLKKRNKPCPVCRQPIQMIVLTYFP 452
TCAKKLKKRNKPCPVCRQPIQMIVLTYFP
Sbjct: 267 TCAKKLKKRNKPCPVCRQPIQMIVLTYFP 295
Score = 105 bits (263), Expect = 6e-23
Identities = 52/54 (96%), Positives = 53/54 (98%)
Query: 7 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEKI 60
MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKE +
Sbjct: 1 MCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEDL 54
>gi|89993690 mouse double minute 2 homolog isoform MDM2a [Homo
sapiens]
Length = 249
Score = 237 bits (604), Expect = 2e-62
Identities = 132/180 (73%), Positives = 133/180 (73%), Gaps = 45/180 (25%)
Query: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKE-- 58
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKE
Sbjct: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
Query: 59 -------------------------------------------KIYTMIYRNLVVVNQQE 75
KIYTMIYRNLVVVNQQE
Sbjct: 61 FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE 120
Query: 76 SSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDE 135
SSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEE D+
Sbjct: 121 SSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEETQDK 180
Score = 168 bits (425), Expect = 1e-41
Identities = 85/108 (78%), Positives = 87/108 (80%), Gaps = 7/108 (6%)
Query: 345 QASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQG 404
Q + S S+PSTSS S E EETQDKEESVESSLPLNAIEPCVICQG
Sbjct: 149 QEEKPSSSHLVSRPSTSSRRRAIS-------ETEETQDKEESVESSLPLNAIEPCVICQG 201
Query: 405 RPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP 452
RPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP
Sbjct: 202 RPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP 249
>gi|89993693 mouse double minute 2 homolog isoform MDM2d [Homo
sapiens]
Length = 172
Score = 193 bits (491), Expect = 2e-49
Identities = 109/159 (68%), Positives = 110/159 (69%), Gaps = 45/159 (28%)
Query: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKE-- 58
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKE
Sbjct: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
Query: 59 -------------------------------------------KIYTMIYRNLVVVNQQE 75
KIYTMIYRNLVVVNQQE
Sbjct: 61 FYLGQYIMTKRLYDEKQQHIVYCSNDLLGDLFGVPSFSVKEHRKIYTMIYRNLVVVNQQE 120
Query: 76 SSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLV 114
SSDSGTSVSENRCHLEGGSDQKDLVQELQEEKP + V
Sbjct: 121 SSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPKTKKRV 159
>gi|89993691 mouse double minute 2 homolog isoform MDM2e [Homo
sapiens]
Length = 179
Score = 175 bits (444), Expect = 7e-44
Identities = 81/81 (100%), Positives = 81/81 (100%)
Query: 372 VKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKK 431
VKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKK
Sbjct: 99 VKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKK 158
Query: 432 RNKPCPVCRQPIQMIVLTYFP 452
RNKPCPVCRQPIQMIVLTYFP
Sbjct: 159 RNKPCPVCRQPIQMIVLTYFP 179
Score = 117 bits (293), Expect = 2e-26
Identities = 58/61 (95%), Positives = 60/61 (98%)
Query: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEKI 60
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKE +
Sbjct: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
Query: 61 Y 61
+
Sbjct: 61 F 61
>gi|88702791 mouse double minute 4 homolog [Homo sapiens]
Length = 490
Score = 165 bits (418), Expect = 7e-41
Identities = 131/482 (27%), Positives = 218/482 (45%), Gaps = 85/482 (17%)
Query: 34 VRPKPLLLKLLKSVGAQKDTYTMKE----------------------------------- 58
VRPK LLK+L + GAQ + +T+KE
Sbjct: 27 VRPKLPLLKILHAAGAQGEMFTVKEVMHYLGQYIMVKQLYDQQEQHMVYCGGDLLGELLG 86
Query: 59 ----------KIYTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKP 108
+Y M+ +NLV + ++D+ +++ + H Q L Q +E
Sbjct: 87 RQSFSVKDPSPLYDMLRKNLVTL-ATATTDAAQTLALAQDHSMDIPSQDQLKQSAEESST 145
Query: 109 SSSHLVSR--PSTSSRRRAISETEENSDELSGERQRKRHKSDSISLSFDE-SLA------ 159
S P+ + + E+ D + Q + + D L F+E +A
Sbjct: 146 SRKRTTEDDIPTLPTSEHKCIHSREDEDLIENLAQDETSRLD---LGFEEWDVAGLPWWF 202
Query: 160 LCVIREICCERSSSSESTGTPSNPDLDAGVSEHSGD--WLDQDSVSDQFSVEFEVESLDS 217
L +R RS+ S T +N D+ + + D W +SVS+Q V +VE+ D+
Sbjct: 203 LGNLRSNYTPRSNGS--TDLQTNQDVGTAIVSDTTDDLWFLNESVSEQLGVGIKVEAADT 260
Query: 218 EDYSLSEEGQELSDEDDEVYQVTVYQAGESD------TDSFEEDPEISLADYWKCTSCNE 271
E SEE ++SD+ V + G++D + S + D E++ D W+CT C +
Sbjct: 261 EQ--TSEEVGKVSDKK-------VIEVGKNDDLEDSKSLSDDTDVEVTSEDEWQCTECKK 311
Query: 272 MNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPDCKKTI---V 328
N P +C RCWALR++W D K +S + EG DVPDC++TI V
Sbjct: 312 FNSPSKRYCFRCWALRKDWY-SDCSKLTHSLSTSDITAIPEKENEGNDVPDCRRTISAPV 370
Query: 329 NDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEESVE 388
+++ +++ + K+ S E D + S S I S E + + T E++E
Sbjct: 371 VRPKDAYIKKENSKLFDPCNSVEFLDLAHSSESQETISSMGEQLDNLSEQRTDT--ENME 428
Query: 389 SSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVL 448
N ++PC +C+ RP++G I+HG+TGHL+ CF CA++LKK CP+C++ IQ+++
Sbjct: 429 DCQ--NLLKPCSLCEKRPRDGNIIHGRTGHLVTCFHCARRLKKAGASCPICKKEIQLVIK 486
Query: 449 TY 450
+
Sbjct: 487 VF 488
>gi|89993692 mouse double minute 2 homolog isoform MDM2b [Homo
sapiens]
Length = 111
Score = 117 bits (293), Expect = 2e-26
Identities = 58/61 (95%), Positives = 60/61 (98%)
Query: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEKI 60
MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKE +
Sbjct: 1 MVRSRQMCNTNMSVPTDGAVTTSQIPASEQETLVRPKPLLLKLLKSVGAQKDTYTMKEVL 60
Query: 61 Y 61
+
Sbjct: 61 F 61
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 59.7 bits (143), Expect = 5e-09
Identities = 74/325 (22%), Positives = 113/325 (34%), Gaps = 20/325 (6%)
Query: 72 NQQESSDSGTSV----SENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAIS 127
N +SSDS S S + + SD D S S S S SS S
Sbjct: 730 NSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSS 789
Query: 128 ETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDA 187
+ ++SD + S S S D + + S SS S+ + + D
Sbjct: 790 NSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSD 849
Query: 188 GVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGES 247
G S + D + SD S DS D S S E SD D + S
Sbjct: 850 GSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDS--------SNSS 901
Query: 248 DTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAK 307
D+DS + +D + +E + S N + N D + S +
Sbjct: 902 DSDSSDSSNSSDSSDSSNSSDSSESSN---SSDNSNSSDSSN---SSDSSDSSDSSNSSD 955
Query: 308 LENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTS--SSII 365
NS+ + D D + +DS S + + +S S +S + S S S SS
Sbjct: 956 SSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDS 1015
Query: 366 YSSQEDVKEFEREETQDKEESVESS 390
+S + + + D +S +SS
Sbjct: 1016 SNSSDSSNSSDSSNSSDSSDSSDSS 1040
Score = 58.9 bits (141), Expect = 9e-09
Identities = 74/337 (21%), Positives = 121/337 (35%), Gaps = 33/337 (9%)
Query: 72 NQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEE 131
N +SSDS S S + SD + + S S S S SS S++ +
Sbjct: 559 NSSDSSDSSDSDSSDS---NSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSD 615
Query: 132 NSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSE 191
+SD + + +SDS S +S + + S S+ S + ++ D+ S
Sbjct: 616 SSDSSDSKSDSSKSESDS---SDSDSKS---------DSSDSNSSDSSDNSDSSDSSNSS 663
Query: 192 HSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDS 251
+S D D SD S S DS D S S E SD D + + S+++S
Sbjct: 664 NSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNS 723
Query: 252 FEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKG--------------- 296
+ D S S + + S+ + ++ D
Sbjct: 724 SDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS 783
Query: 297 --KDKGEISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESED 354
D S+ + NS+ + D D + +DS S N + +S S +S D
Sbjct: 784 DSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSD 843
Query: 355 YSQPSTSSSIIYSSQED-VKEFEREETQDKEESVESS 390
S S S S++ D + ++ D S +SS
Sbjct: 844 SSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSS 880
Score = 55.8 bits (133), Expect = 8e-08
Identities = 65/321 (20%), Positives = 122/321 (38%), Gaps = 14/321 (4%)
Query: 72 NQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEE 131
++ +D S S+N S + D E K + + S+ + + S+T
Sbjct: 469 DESNGNDDANSESDNN-----SSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNN 523
Query: 132 NSDELSGERQRKRH-KSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVS 190
+ +G + KSDS D S + + S SS+S + SN D+ S
Sbjct: 524 SDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSS 583
Query: 191 EH-SGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDT 249
+ S D D DS S DS D S S + + SD D + ++ SD+
Sbjct: 584 DSDSSDSSDSDSSDSS-------NSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDS 636
Query: 250 DSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKAKLE 309
DS + + + +D + ++ + S + + + + + S+ +
Sbjct: 637 DSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSS 696
Query: 310 NSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQ 369
NS+++ + D D + +DS S ++D + S + S S+ SS S
Sbjct: 697 NSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSS 756
Query: 370 EDVKEFEREETQDKEESVESS 390
+ ++ D +S +SS
Sbjct: 757 DSSDSSNSSDSSDSSDSSDSS 777
Score = 37.0 bits (84), Expect = 0.037
Identities = 51/229 (22%), Positives = 84/229 (36%), Gaps = 30/229 (13%)
Query: 175 ESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQF-SVEFEVESLDSEDYSLSEEGQELSDED 233
E G S P G S D S SD + S +F+ +S+ +D + S+E D +
Sbjct: 424 EGPGQKSEPGNKVGHSNTGSD-----SNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDAN 478
Query: 234 DEVYQVTV------YQAGES-------DTDSFEEDPEISLADYWKCTSCNEMNPPLPSHC 280
E + Y + ES D+ E+D S +D S N +
Sbjct: 479 SESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDND 538
Query: 281 NRCWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEEND 340
KGK S+ + NS+ + + D +DS S + +D
Sbjct: 539 KS---------DSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSD 589
Query: 341 DKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEESVES 389
+ +S S S D S S SS S D + + + ++ + +S +S
Sbjct: 590 SSDSDSSDSSNSSDSSDSSDSSD--SSDSSDSSDSKSDSSKSESDSSDS 636
Score = 33.9 bits (76), Expect = 0.31
Identities = 51/226 (22%), Positives = 90/226 (39%), Gaps = 36/226 (15%)
Query: 126 ISETEENSDELSGERQRKRHKSDSISLSF-DESLALCVIREICCERSSSSESTGTPSNPD 184
++ +E+ +++G ++ + I S +E + +I +R+ + E+ TP +
Sbjct: 176 VAVVQEDGPQVAGSNNSTDNEDEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPGTGE 235
Query: 185 LDAGVSEH----SGDWLDQDSVSDQFSVEFEVESL----DSEDYSLSEEGQELSDEDDEV 236
DAG+ SG+ D+D D+ S + E E DS + S +EGQ+ EDD
Sbjct: 236 -DAGLDNSDGSPSGNGADEDE--DEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHD 292
Query: 237 YQVTVYQAGESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKG 296
+ G++ DPE K NE++ S +PED G
Sbjct: 293 SSI-----GQNSDSKEYYDPE------GKEDPHNEVDGDKTSKSEE----NSAGIPEDNG 337
Query: 297 KDKGEISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDK 342
+ E ++K S + E I +S V ++ DK
Sbjct: 338 SQRIEDTQKLNHRESKRVE---------NRITKESETHAVGKSQDK 374
>gi|190194423 SPARC-like 1 [Homo sapiens]
Length = 664
Score = 46.2 bits (108), Expect = 6e-05
Identities = 89/410 (21%), Positives = 154/410 (37%), Gaps = 83/410 (20%)
Query: 71 VNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSS-----RRRA 125
+ QE SD SV+ EG D K+ + E QE+K S + P SS ++ +
Sbjct: 97 LKDQEDSDGHLSVNLEYAPTEGTLDIKEDMSEPQEKKLSENTDFLAPGVSSFTDSNQQES 156
Query: 126 ISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDL 185
I++ EEN ++ + ++S S +R+ + + S G
Sbjct: 157 ITKREENQEQPRNYSHHQLNRSSKHSQG---------LRDQGNQEQDPNISNGEEEEEKE 207
Query: 186 DAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAG 245
V H+ + + E E +S+ + + ++ +E D+ QV+ Q
Sbjct: 208 PGEVGTHNDN--------QERKTELPREHANSKQEEDNTQSDDILEESDQPTQVSKMQED 259
Query: 246 ESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGE-ISE 304
E D + E++ S EM S+ N+ ++E +GK E IS
Sbjct: 260 EFDQGNQEQEDN----------SNAEMEEENASNVNK--HIQETEWQSQEGKTGLEAISN 307
Query: 305 KAKLENSTQAEEGFDVP--DCKKTIVNDSRESCVEEN-DDKITQASQSQESEDYSQPS-- 359
+ E T +E P D T N + +++ DD T + S+DY PS
Sbjct: 308 HKETEEKTVSEALLMEPTDDGNTTPRNHGVDDDGDDDGDDGGTDGPRHSASDDYFIPSQA 367
Query: 360 -----TSSSIIY-----SSQEDVKEFE----------------REETQDKEESVESSLPL 393
+ SI Y +E V E E + ++E S E ++ +
Sbjct: 368 FLEAERAQSIAYHLKIEEQREKVHENENIGTTEPGEHQEAKKAENSSNEEETSSEGNMRV 427
Query: 394 NAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPI 443
+A++ C+ Q C K GH+ K ++ KP VC+ P+
Sbjct: 428 HAVDSCMSFQ------C----KRGHIC-------KADQQGKPHCVCQDPV 460
>gi|190341024 SPARC-like 1 [Homo sapiens]
Length = 664
Score = 46.2 bits (108), Expect = 6e-05
Identities = 89/410 (21%), Positives = 154/410 (37%), Gaps = 83/410 (20%)
Query: 71 VNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSS-----RRRA 125
+ QE SD SV+ EG D K+ + E QE+K S + P SS ++ +
Sbjct: 97 LKDQEDSDGHLSVNLEYAPTEGTLDIKEDMSEPQEKKLSENTDFLAPGVSSFTDSNQQES 156
Query: 126 ISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDL 185
I++ EEN ++ + ++S S +R+ + + S G
Sbjct: 157 ITKREENQEQPRNYSHHQLNRSSKHSQG---------LRDQGNQEQDPNISNGEEEEEKE 207
Query: 186 DAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAG 245
V H+ + + E E +S+ + + ++ +E D+ QV+ Q
Sbjct: 208 PGEVGTHNDN--------QERKTELPREHANSKQEEDNTQSDDILEESDQPTQVSKMQED 259
Query: 246 ESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGE-ISE 304
E D + E++ S EM S+ N+ ++E +GK E IS
Sbjct: 260 EFDQGNQEQEDN----------SNAEMEEENASNVNK--HIQETEWQSQEGKTGLEAISN 307
Query: 305 KAKLENSTQAEEGFDVP--DCKKTIVNDSRESCVEEN-DDKITQASQSQESEDYSQPS-- 359
+ E T +E P D T N + +++ DD T + S+DY PS
Sbjct: 308 HKETEEKTVSEALLMEPTDDGNTTPRNHGVDDDGDDDGDDGGTDGPRHSASDDYFIPSQA 367
Query: 360 -----TSSSIIY-----SSQEDVKEFE----------------REETQDKEESVESSLPL 393
+ SI Y +E V E E + ++E S E ++ +
Sbjct: 368 FLEAERAQSIAYHLKIEEQREKVHENENIGTTEPGEHQEAKKAENSSNEEETSSEGNMRV 427
Query: 394 NAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPI 443
+A++ C+ Q C K GH+ K ++ KP VC+ P+
Sbjct: 428 HAVDSCMSFQ------C----KRGHIC-------KADQQGKPHCVCQDPV 460
>gi|88759348 ring finger protein 219 [Homo sapiens]
Length = 726
Score = 43.1 bits (100), Expect = 5e-04
Identities = 48/197 (24%), Positives = 74/197 (37%), Gaps = 12/197 (6%)
Query: 94 SDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRHKSDSISLS 153
S + D+ + E+K S S P T + +N D S E + IS
Sbjct: 442 SSEDDISRSENEKK---SECFSSPKTGFWDCCSTSYAQNLDFESSEGNTIANSVGEISSK 498
Query: 154 FDESLALCVIREICCERSSSSESTGTPSNPDLDAG----VSEHSGDWLDQDSVSDQFSVE 209
E LC+ + + RS T T S +DA +SE + D+ +
Sbjct: 499 LSEKSGLCLSKRLNSIRSFEMNRTRTSSEASMDAAYLDKISELDSMMSESDNSKSPCNNG 558
Query: 210 FEVESLDSEDYSLSEEGQELSDEDDEVYQVTV--YQAGESDTDSFEEDPEISLADYWKCT 267
F +SLD + S S +G E +E D++ + T G D E E ++ +
Sbjct: 559 F--KSLDLDGLSKSSQGSEFLEEPDKLEEKTELNLSKGSLTNDQLENGSEWKPTSFFLLS 616
Query: 268 -SCNEMNPPLPSHCNRC 283
S EMN H + C
Sbjct: 617 PSDQEMNEDFSLHSSSC 633
Score = 28.9 bits (63), Expect = 10.0
Identities = 15/45 (33%), Positives = 19/45 (42%), Gaps = 3/45 (6%)
Query: 399 CVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPCPVCRQPI 443
C IC G+ + I + + C C K N CP CR PI
Sbjct: 18 CHICLGKVRQPVIC---INNHVFCSICIDLWLKNNSQCPACRVPI 59
>gi|223278368 neuralized-like [Homo sapiens]
Length = 574
Score = 42.0 bits (97), Expect = 0.001
Identities = 24/70 (34%), Positives = 35/70 (50%), Gaps = 11/70 (15%)
Query: 390 SLPLNAIEP--------CVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKR-NKPCPVCR 440
SLP + + P C IC + I GH+ C+ C +LKK + CP+CR
Sbjct: 504 SLPESPVTPGLGQWSDECTICYEHAVDTVIY--TCGHMCLCYACGLRLKKALHACCPICR 561
Query: 441 QPIQMIVLTY 450
+PI+ I+ TY
Sbjct: 562 RPIKDIIKTY 571
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 42.0 bits (97), Expect = 0.001
Identities = 43/192 (22%), Positives = 77/192 (40%), Gaps = 17/192 (8%)
Query: 85 ENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETE---------ENSDE 135
E R E +K +E +E L+++ +R RA + + + D
Sbjct: 379 EERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDS 438
Query: 136 LSGER------QRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGV 189
L +R +RK+ S ES+ LC E+ + E T P P+ +
Sbjct: 439 LPKKRPIYEDKKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEPEEEEDT 498
Query: 190 SEHS-GDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESD 248
+ DW S + VE ++ ++ EE +E +E+DE + + GES+
Sbjct: 499 EDAGLDDWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESE 558
Query: 249 -TDSFEEDPEIS 259
++ EED ++S
Sbjct: 559 GSEGDEEDEKVS 570
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 41.6 bits (96), Expect = 0.001
Identities = 32/135 (23%), Positives = 58/135 (42%), Gaps = 16/135 (11%)
Query: 123 RRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSN 182
RRA S T + S+ + E R+ +S S E+ E S TG+ +
Sbjct: 142 RRAKSPTPDGSERIGLEVDRRASRSSQSSKE-----------EVNSEEYGSDHETGSSGS 190
Query: 183 PDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVY 242
D +E+ + +++D D+ EVE ED + E+G+E +E++E +
Sbjct: 191 SDEQGNNTENEEEGVEEDVEEDE-----EVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEE 245
Query: 243 QAGESDTDSFEEDPE 257
+ E + D ++ E
Sbjct: 246 EEEEYEQDERDQKEE 260
Score = 32.3 bits (72), Expect = 0.90
Identities = 28/132 (21%), Positives = 53/132 (40%), Gaps = 16/132 (12%)
Query: 123 RRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSN 182
RRA ++ + +E++ E H++ S S ++ ++ +E G +
Sbjct: 161 RRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQG------------NNTENEEEGVEED 208
Query: 183 PDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVY 242
+ D V E + ++D D+ E E E + E+ EE + DE D+ + Y
Sbjct: 209 VEEDEEVEEDA----EEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDY 264
Query: 243 QAGESDTDSFEE 254
+DS E
Sbjct: 265 DTRSEASDSGSE 276
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 41.6 bits (96), Expect = 0.001
Identities = 32/135 (23%), Positives = 58/135 (42%), Gaps = 16/135 (11%)
Query: 123 RRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSN 182
RRA S T + S+ + E R+ +S S E+ E S TG+ +
Sbjct: 142 RRAKSPTPDGSERIGLEVDRRASRSSQSSKE-----------EVNSEEYGSDHETGSSGS 190
Query: 183 PDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVY 242
D +E+ + +++D D+ EVE ED + E+G+E +E++E +
Sbjct: 191 SDEQGNNTENEEEGVEEDVEEDE-----EVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEE 245
Query: 243 QAGESDTDSFEEDPE 257
+ E + D ++ E
Sbjct: 246 EEEEYEQDERDQKEE 260
Score = 32.3 bits (72), Expect = 0.90
Identities = 28/132 (21%), Positives = 53/132 (40%), Gaps = 16/132 (12%)
Query: 123 RRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSN 182
RRA ++ + +E++ E H++ S S ++ ++ +E G +
Sbjct: 161 RRASRSSQSSKEEVNSEEYGSDHETGSSGSSDEQG------------NNTENEEEGVEED 208
Query: 183 PDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVY 242
+ D V E + ++D D+ E E E + E+ EE + DE D+ + Y
Sbjct: 209 VEEDEEVEEDA----EEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYEQDERDQKEEGNDY 264
Query: 243 QAGESDTDSFEE 254
+DS E
Sbjct: 265 DTRSEASDSGSE 276
>gi|33946285 baculoviral IAP repeat-containing protein 3 [Homo
sapiens]
Length = 604
Score = 40.8 bits (94), Expect = 0.003
Identities = 29/83 (34%), Positives = 38/83 (45%), Gaps = 9/83 (10%)
Query: 369 QEDVKEFEREETQDKEESVESSLP-LNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAK 427
Q+D+K E+ D VE L L C +C K IV GHL+ C CA
Sbjct: 528 QQDIKYIPTEDVSDLP--VEEQLRRLQEERTCKVCMD--KEVSIVFIPCGHLVVCKDCAP 583
Query: 428 KLKKRNKPCPVCRQPIQMIVLTY 450
L+K CP+CR I+ V T+
Sbjct: 584 SLRK----CPICRSTIKGTVRTF 602
>gi|4502139 baculoviral IAP repeat-containing protein 3 [Homo
sapiens]
Length = 604
Score = 40.8 bits (94), Expect = 0.003
Identities = 29/83 (34%), Positives = 38/83 (45%), Gaps = 9/83 (10%)
Query: 369 QEDVKEFEREETQDKEESVESSLP-LNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAK 427
Q+D+K E+ D VE L L C +C K IV GHL+ C CA
Sbjct: 528 QQDIKYIPTEDVSDLP--VEEQLRRLQEERTCKVCMD--KEVSIVFIPCGHLVVCKDCAP 583
Query: 428 KLKKRNKPCPVCRQPIQMIVLTY 450
L+K CP+CR I+ V T+
Sbjct: 584 SLRK----CPICRSTIKGTVRTF 602
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 40.4 bits (93), Expect = 0.003
Identities = 70/361 (19%), Positives = 141/361 (39%), Gaps = 63/361 (17%)
Query: 54 YTMKEKIYTMIYRNLVVVNQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHL 113
YT K + Y+ + + GT + ++ G +++ EEK +
Sbjct: 104 YTSKTHLKKAEYK------KSKDEKGGTPLKKDSKKKGGSYATNPESKQIVEEKTKRQNE 157
Query: 114 VSR-PSTSSRRRAISETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSS 172
+ P SS S+ ++S E + E Q + S + S ++ + +
Sbjct: 158 ADKTPLKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQKDK--------KDSKNSKKT 209
Query: 173 SSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEG--QELS 230
++E T +NP D S+ S D + + + +V+F + S+D S++ + + S
Sbjct: 210 NTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWLRNYS 269
Query: 231 DEDDEVYQVTVYQAGESDT--------DSFEEDPEISLADYWKCTSCNEMNPPLPSHCNR 282
+ + Y + + + DT D+ ED + + D K
Sbjct: 270 QNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKK----------------- 312
Query: 283 CWALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPDCKKTIVNDSR--------ES 334
+++N +DK KD + +E E+ +E D KK + D + ES
Sbjct: 313 ---VKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPES 369
Query: 335 CVEENDD---------KITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEE 385
E+ D + +AS++ + + ++ T S+ S E KE +++E +DK++
Sbjct: 370 TDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELES-KESQKDEKKDKKD 428
Query: 386 S 386
S
Sbjct: 429 S 429
>gi|16445033 ACRC protein [Homo sapiens]
Length = 691
Score = 39.7 bits (91), Expect = 0.006
Identities = 54/207 (26%), Positives = 79/207 (38%), Gaps = 20/207 (9%)
Query: 72 NQQESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAI----S 127
N +SSD + S+ SD D + + SS P SS S
Sbjct: 200 NSDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSS 259
Query: 128 ETEENSDELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDA 187
+ E D+ S + + SD S D S + +S +S+ PD +
Sbjct: 260 DDSEAPDDSSDDSEAPDDSSDDSEASDDSS----------DDSEASDDSSDDSEAPDDKS 309
Query: 188 GVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGES 247
S+ D D V D S + EV + +ED L EGQ SDE++ V +S
Sbjct: 310 DDSDVPEDKSDDSDVPDDNSDDLEVP-VPAED--LCNEGQIASDEEELVEAAAAVSQHDS 366
Query: 248 DTDSFEEDPEISLADYWKCTSCNEMNP 274
D+ E+D +L+ K S E NP
Sbjct: 367 SDDAGEQDLGENLS---KPPSDPEANP 390
Score = 37.0 bits (84), Expect = 0.037
Identities = 37/181 (20%), Positives = 69/181 (38%), Gaps = 4/181 (2%)
Query: 75 ESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSD 134
++SD + +N E D D E ++ S + P +S + ++++SD
Sbjct: 151 DNSDDSEAPDDNSDDSEAPDDNSD-DSEAPDDNSDDSDV---PDDNSDDSSDDNSDDSSD 206
Query: 135 ELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHSG 194
+ S + KSD + D S V + + + +S+ PD + SE
Sbjct: 207 DNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSSDDSEAPDDSSDDSEAPDDSSDDSEAPD 266
Query: 195 DWLDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEE 254
D D D S + E S+D S++ + S+ D+ + +SD +
Sbjct: 267 DSSDDSEAPDDSSDDSEASDDSSDDSEASDDSSDDSEAPDDKSDDSDVPEDKSDDSDVPD 326
Query: 255 D 255
D
Sbjct: 327 D 327
Score = 36.6 bits (83), Expect = 0.048
Identities = 72/349 (20%), Positives = 131/349 (37%), Gaps = 59/349 (16%)
Query: 70 VVNQQESSD--SGTSVSENRCHLEGGSDQKDLVQELQEEK-PSSSHLVSRPSTSSRRRAI 126
++N Q SSD SG+SV+ Q + +Q +S V+R + + ++
Sbjct: 22 ILNVQSSSDDTSGSSVARR-----APKRQASCILNVQSRSGDTSGSSVARRAPKRQASSV 76
Query: 127 SETEENSDELSGERQRKRHKSDSISLSFDESLALCVIR---------------------- 164
+ +SDE + K+ K I+ S DES C ++
Sbjct: 77 VVIDSDSDEECHTHEEKKAKLLEIN-SDDESPECCHVKPAIQEPPIVISDDDNDDDNGND 135
Query: 165 -EICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDYSLS 223
E+ + S SE+ PD ++ SE D D D S + E +S+D +
Sbjct: 136 LEVPDDNSDDSEA------PDDNSDDSEAPDDNSDDSEAPDDNSDDSEAPDDNSDDSDVP 189
Query: 224 EEGQELSDEDDEVYQVTVYQAGESDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRC 283
++ + S +D+ SD +S + D +D + + +P +
Sbjct: 190 DDNSDDSSDDN--------SDDSSDDNSDDSDVPDDKSDDSDVPDDSSDDSDVPDDSS-- 239
Query: 284 WALRENWLPEDKGKDKGEISEKAKLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKI 343
++ P+D D +A ++S +E D D + + S +S E +DD
Sbjct: 240 ---DDSEAPDDSSDD-----SEAPDDSSDDSEAPDDSSDDSEAPDDSSDDS--EASDDSS 289
Query: 344 TQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEESVESSLP 392
+ S +S D S+ S ED K + + D + +E +P
Sbjct: 290 DDSEASDDSSDDSEAPDDKSDDSDVPED-KSDDSDVPDDNSDDLEVPVP 337
>gi|124517695 ankyrin repeat domain 36B [Homo sapiens]
Length = 1121
Score = 39.7 bits (91), Expect = 0.006
Identities = 60/287 (20%), Positives = 114/287 (39%), Gaps = 39/287 (13%)
Query: 74 QESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENS 133
++ SGT S+ + L+ SD+KD + EK +SR +S + A+ T
Sbjct: 185 KDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGE--ISRTVSSQKPPALKATSVKE 242
Query: 134 DELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHS 193
D + + K+ S ++SF++ L R+ E+ S + + VS H
Sbjct: 243 DSVLNIAREKKDGEKSRTVSFEQPPGLKATRD---EKDSLLNIARGKKDGEKTRRVSSHK 299
Query: 194 GDWLDQDSVSDQFSVEFEVESLDSE-DYSLSEEGQ----ELSDEDDEVYQV--TVYQAGE 246
L S + E+ D + ++S + Q SD+ D V + + +
Sbjct: 300 QPSLKATSDKEDSVPNMATETKDEQISGTVSCQKQPALKATSDKKDSVSNIPTEIKDGQQ 359
Query: 247 SDTDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKA 306
S T S ++ P WK TS + S N +++ G+ +G +S +
Sbjct: 360 SGTVSSQKQPA------WKATSVKK-----DSVSNIATEIKD-------GQIRGTVSSQR 401
Query: 307 KLENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESE 353
+ T +E K ++ N +RE +++ + T + Q Q ++
Sbjct: 402 RPALKTTGDE-------KDSVSNIARE--IKDGEKSGTVSPQKQSAQ 439
>gi|217416388 neuralized homolog 1B [Homo sapiens]
Length = 555
Score = 39.3 bits (90), Expect = 0.007
Identities = 33/120 (27%), Positives = 52/120 (43%), Gaps = 17/120 (14%)
Query: 350 QESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRP--- 406
Q S + PS S S + F ++ ES + P + + P V P
Sbjct: 436 QSSPATTTPSGSLSGSQDDSDSDMTFSVNQSSSASESSLVTAPSSPLSPPVSPVFSPPEP 495
Query: 407 ---KNG-CIV--HGKT-------GHLMACFTCAKKLKKRNKPC-PVCRQPIQMIVLTYFP 452
KNG C V G+ GH+ C +C +LK++ + C P+CR+PI+ ++ Y P
Sbjct: 496 AGIKNGECTVCFDGEVDTVIYTCGHMCLCHSCGLRLKRQARACCPICRRPIKDVIKIYRP 555
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 39.3 bits (90), Expect = 0.007
Identities = 62/279 (22%), Positives = 98/279 (35%), Gaps = 39/279 (13%)
Query: 101 QELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRHKSDSISLSFDESLAL 160
++ + S L+ PS R++ E++ EL + KSDS S L
Sbjct: 247 EQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGL 306
Query: 161 CVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDY 220
R R S +S D +S+ + D S + S E + S E+
Sbjct: 307 SQPR-----RDSKGDS-----QEDSKENLSQEESQ--NVDGPSSESSQEANLSS--QENS 352
Query: 221 SLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEEDPEISL-----------ADYWKCTSC 269
S S+E D T Y + D+DS EED +L AD S
Sbjct: 353 SESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESL 412
Query: 270 N--EMNPPLP------------SHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAE 315
N E +P P SH + + E E+ D + S + NST+++
Sbjct: 413 NFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESK 472
Query: 316 EGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESED 354
+ K I +SR+ V+ +K + +D
Sbjct: 473 SSSEEDGQLKNIEIESRKLTVDAYHNKPIGDQDDNDCQD 511
Score = 35.4 bits (80), Expect = 0.11
Identities = 66/337 (19%), Positives = 119/337 (35%), Gaps = 65/337 (19%)
Query: 91 EGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRA----ISETEENSDELSGERQRKRHK 146
+GG D+ D + ++ S P R+ + E++ D + +
Sbjct: 97 KGGDDKDDDEDDSGDDTFGDDD--SGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQG 154
Query: 147 SDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDA------GVSEHSGDWLDQD 200
DS + ES RE+ E S+ G S + ++ G S+ D
Sbjct: 155 QDSAQDTTSES------RELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGS 208
Query: 201 SVSDQFSVEFEVESLDSE--DYSLSEEGQELSDEDDEVYQVTVYQAGESD---------- 248
+ D+ + ES+ SE + ++ G + + + Q +G S
Sbjct: 209 ELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIF 268
Query: 249 --TDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKA 306
+ EED L D + E+ + N R+ L + + KG+ E +
Sbjct: 269 RKSRISEEDDRSELDDN---NTMEEVKSDSTENSNS----RDTGLSQPRRDSKGDSQEDS 321
Query: 307 KLENSTQAEEGFDVP-----------------DCKKTIVNDSRESCVEENDDKITQASQS 349
K S + + D P + ++ +V++SR +N D T +
Sbjct: 322 KENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESR----GDNPDPTTSYVED 377
Query: 350 QESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEES 386
QE D S+ +S ++ +S E REE D E S
Sbjct: 378 QEDSDSSEEDSSHTLSHSKSE-----SREEQADSESS 409
Score = 35.0 bits (79), Expect = 0.14
Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 12/110 (10%)
Query: 287 RENWLPEDKGKDKG---EISEKAKL---ENSTQAEEGF------DVPDCKKTIVNDSRES 334
+EN E+ G E S++A L ENS++++E D PD + V D +S
Sbjct: 322 KENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDS 381
Query: 335 CVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKE 384
E D T + ES + S SS + S+E + E E + +E
Sbjct: 382 DSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQE 431
Score = 33.5 bits (75), Expect = 0.41
Identities = 43/184 (23%), Positives = 76/184 (41%), Gaps = 15/184 (8%)
Query: 79 SGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSG 138
S S ++R L+ + +++ + E S +S+P RR + +++E+S E
Sbjct: 271 SRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQP----RRDSKGDSQEDSKENLS 326
Query: 139 ERQRKRHKSDSISLSFDESLALCVIREICCERSSS--SESTGTPSNPDLDAGVSEHSGDW 196
+ + + S S + +L+ +E E SES G +P + D
Sbjct: 327 QEESQNVDGPSSESSQEANLS---SQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDS 383
Query: 197 LDQDSV-----SDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDS 251
++DS S S E + +S SE + SEE E S ED+ Q+ S +S
Sbjct: 384 SEEDSSHTLSHSKSESREEQADSESSESLNFSEESPE-SPEDENSSSQEGLQSHSSSAES 442
Query: 252 FEED 255
E+
Sbjct: 443 QSEE 446
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 39.3 bits (90), Expect = 0.007
Identities = 62/279 (22%), Positives = 98/279 (35%), Gaps = 39/279 (13%)
Query: 101 QELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSGERQRKRHKSDSISLSFDESLAL 160
++ + S L+ PS R++ E++ EL + KSDS S L
Sbjct: 231 EQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGL 290
Query: 161 CVIREICCERSSSSESTGTPSNPDLDAGVSEHSGDWLDQDSVSDQFSVEFEVESLDSEDY 220
R R S +S D +S+ + D S + S E + S E+
Sbjct: 291 SQPR-----RDSKGDS-----QEDSKENLSQEESQ--NVDGPSSESSQEANLSS--QENS 336
Query: 221 SLSEEGQELSDEDDEVYQVTVYQAGESDTDSFEEDPEISL-----------ADYWKCTSC 269
S S+E D T Y + D+DS EED +L AD S
Sbjct: 337 SESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESL 396
Query: 270 N--EMNPPLP------------SHCNRCWALRENWLPEDKGKDKGEISEKAKLENSTQAE 315
N E +P P SH + + E E+ D + S + NST+++
Sbjct: 397 NFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESK 456
Query: 316 EGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESED 354
+ K I +SR+ V+ +K + +D
Sbjct: 457 SSSEEDGQLKNIEIESRKLTVDAYHNKPIGDQDDNDCQD 495
Score = 35.4 bits (80), Expect = 0.11
Identities = 66/337 (19%), Positives = 119/337 (35%), Gaps = 65/337 (19%)
Query: 91 EGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRA----ISETEENSDELSGERQRKRHK 146
+GG D+ D + ++ S P R+ + E++ D + +
Sbjct: 81 KGGDDKDDDEDDSGDDTFGDDD--SGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQG 138
Query: 147 SDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDA------GVSEHSGDWLDQD 200
DS + ES RE+ E S+ G S + ++ G S+ D
Sbjct: 139 QDSAQDTTSES------RELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGS 192
Query: 201 SVSDQFSVEFEVESLDSE--DYSLSEEGQELSDEDDEVYQVTVYQAGESD---------- 248
+ D+ + ES+ SE + ++ G + + + Q +G S
Sbjct: 193 ELDDEGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIF 252
Query: 249 --TDSFEEDPEISLADYWKCTSCNEMNPPLPSHCNRCWALRENWLPEDKGKDKGEISEKA 306
+ EED L D + E+ + N R+ L + + KG+ E +
Sbjct: 253 RKSRISEEDDRSELDDN---NTMEEVKSDSTENSNS----RDTGLSQPRRDSKGDSQEDS 305
Query: 307 KLENSTQAEEGFDVP-----------------DCKKTIVNDSRESCVEENDDKITQASQS 349
K S + + D P + ++ +V++SR +N D T +
Sbjct: 306 KENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESR----GDNPDPTTSYVED 361
Query: 350 QESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKEES 386
QE D S+ +S ++ +S E REE D E S
Sbjct: 362 QEDSDSSEEDSSHTLSHSKSE-----SREEQADSESS 393
Score = 35.0 bits (79), Expect = 0.14
Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 12/110 (10%)
Query: 287 RENWLPEDKGKDKG---EISEKAKL---ENSTQAEEGF------DVPDCKKTIVNDSRES 334
+EN E+ G E S++A L ENS++++E D PD + V D +S
Sbjct: 306 KENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDS 365
Query: 335 CVEENDDKITQASQSQESEDYSQPSTSSSIIYSSQEDVKEFEREETQDKE 384
E D T + ES + S SS + S+E + E E + +E
Sbjct: 366 DSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQE 415
Score = 33.5 bits (75), Expect = 0.41
Identities = 43/184 (23%), Positives = 76/184 (41%), Gaps = 15/184 (8%)
Query: 79 SGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENSDELSG 138
S S ++R L+ + +++ + E S +S+P RR + +++E+S E
Sbjct: 255 SRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQP----RRDSKGDSQEDSKENLS 310
Query: 139 ERQRKRHKSDSISLSFDESLALCVIREICCERSSS--SESTGTPSNPDLDAGVSEHSGDW 196
+ + + S S + +L+ +E E SES G +P + D
Sbjct: 311 QEESQNVDGPSSESSQEANLS---SQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDS 367
Query: 197 LDQDSV-----SDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDS 251
++DS S S E + +S SE + SEE E S ED+ Q+ S +S
Sbjct: 368 SEEDSSHTLSHSKSESREEQADSESSESLNFSEESPE-SPEDENSSSQEGLQSHSSSAES 426
Query: 252 FEED 255
E+
Sbjct: 427 QSEE 430
>gi|239753245 PREDICTED: similar to UPF0634 protein C [Homo sapiens]
Length = 710
Score = 39.3 bits (90), Expect = 0.007
Identities = 68/318 (21%), Positives = 118/318 (37%), Gaps = 39/318 (12%)
Query: 74 QESSDSGTSVSENRCHLEGGSDQKDLVQELQEEKPSSSHLVSRPSTSSRRRAISETEENS 133
++ SGT S+ + L+ SD+KD + EK +SR +S + A+ T
Sbjct: 220 KDGEKSGTVSSQKKPALKATSDEKDSFSNITREKKDGE--ISRTVSSQKPPALKATSVKE 277
Query: 134 DELSGERQRKRHKSDSISLSFDESLALCVIREICCERSSSSESTGTPSNPDLDAGVSEHS 193
D + + K+ S ++SFD+ L R+ E+ S N + VS
Sbjct: 278 DSVLNIAREKKDGEKSRTVSFDQPPGLKATRD---EKDSLLNIARGKKNGEKTRRVSSRK 334
Query: 194 GDWLDQDS-VSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGESDTDSF 252
L S D FS + + ++ E+S + T+ G SD
Sbjct: 335 KPALKATSDEKDSFS-----------NITRGKKDGEISRKVSSQKPPTL--KGTSD---- 377
Query: 253 EEDPEISLA----DYWKCTSCNEMNPP-LPSHCNRCWALRENWLPEDKGKDKGEISEKAK 307
EED + +A D K + + PP L + + +++ L +GK GE +++
Sbjct: 378 EEDSVLGIARENKDGEKSRTVSSEKPPGLKASSDE----KDSVLNIARGKKYGEKTKRVS 433
Query: 308 LENSTQAEEGFDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQPSTSSSIIYS 367
E D D I E+ D +I++ SQ+ S +
Sbjct: 434 SRKKPSLEATSDEKDSFSNITR-------EKKDGEISRKVSSQKPPALKGTSDEEDSVLG 486
Query: 368 SQEDVKEFEREETQDKEE 385
+ K+ E+ T E+
Sbjct: 487 IARENKDGEKSRTVSSEK 504
>gi|58743365 ring finger protein 157 [Homo sapiens]
Length = 679
Score = 39.3 bits (90), Expect = 0.007
Identities = 26/91 (28%), Positives = 43/91 (47%), Gaps = 4/91 (4%)
Query: 357 QPSTSSSIIYSSQEDVKEFEREETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKT 416
Q + Y QE + TQD + + E + N+ E CV+C ++ I+ +
Sbjct: 237 QKQVVDGVSYLLQEIYGIENKYNTQDSKVA-EDEVSDNSAE-CVVCLSDVRDTLILPCR- 293
Query: 417 GHLMACFTCAKKLKKRNKPCPVCRQPIQMIV 447
HL C TCA L+ + CP+CR P + ++
Sbjct: 294 -HLCLCNTCADTLRYQANNCPICRLPFRALL 323
>gi|38788243 myosin regulatory light chain interacting protein [Homo
sapiens]
Length = 445
Score = 39.3 bits (90), Expect = 0.007
Identities = 32/136 (23%), Positives = 60/136 (44%), Gaps = 15/136 (11%)
Query: 318 FDVPDCKKTIVNDSRESCVEENDDKITQASQSQESEDYSQ-PSTSSSIIYSSQEDVKEFE 376
FD+ K + + +R + N + S++ +S +S S+ SS+ SS E + +
Sbjct: 313 FDIKRTSKEVYDHARRALY--NAGVVDLVSRNNQSPSHSPLKSSESSMNCSSCEGLSCQQ 370
Query: 377 REETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHGKTGHLMACFTCAKKLKKRNKPC 436
Q+K ++ ++ C++C N GH + C +CA +L+ C
Sbjct: 371 TRVLQEKLRKLKEAML------CMVCCEEEINSTFC--PCGHTVCCESCAAQLQS----C 418
Query: 437 PVCRQPIQMIVLTYFP 452
PVCR ++ + Y P
Sbjct: 419 PVCRSRVEHVQHVYLP 434
>gi|39780588 TSR1, 20S rRNA accumulation [Homo sapiens]
Length = 804
Score = 39.3 bits (90), Expect = 0.007
Identities = 24/90 (26%), Positives = 43/90 (47%), Gaps = 3/90 (3%)
Query: 188 GVSEHSGDW-LDQDSVSDQFSVEFEVESLDSEDYSLSEEGQELSDEDDEVYQVTVYQAGE 246
G S + +W LD S S E+E + ++ ED+ E E S+E++E +T+ ++
Sbjct: 396 GTSSYQAEWILDGGSQSGGEGDEYEYDDMEHEDFMEEESQDESSEEEEEYETMTIGESVH 455
Query: 247 SD--TDSFEEDPEISLADYWKCTSCNEMNP 274
D +E+ E + + +K EM P
Sbjct: 456 DDLYDKKVDEEAEAKMLEKYKQERLEEMFP 485
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.125 0.355
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,343,612
Number of Sequences: 37866
Number of extensions: 896752
Number of successful extensions: 5283
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 279
Number of HSP's that attempted gapping in prelim test: 4467
Number of HSP's gapped (non-prelim): 924
length of query: 452
length of database: 18,247,518
effective HSP length: 106
effective length of query: 346
effective length of database: 14,233,722
effective search space: 4924867812
effective search space used: 4924867812
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.