Guide to the Human Genome
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Name: MDM2 Sequence: fasta or formatted (497aa) NCBI GI: 89993689
Description:

mouse double minute 2 homolog isoform MDM2

Referenced in:

p53 Pathway
Ubiquitin and Related Protein Modifications

Other entries for this name:
alt prot [452aa] mouse double minute 2 homolog isoform MDM2f
alt prot [444aa] mouse double minute 2 homolog isoform MDM2g
alt prot [442aa] mouse double minute 2 homolog isoform MDM2h
alt prot [295aa] mouse double minute 2 homolog isoform MDM2i
alt prot [249aa] mouse double minute 2 homolog isoform MDM2a
alt prot [179aa] mouse double minute 2 homolog isoform MDM2e
alt prot [111aa] mouse double minute 2 homolog isoform MDM2b
alt prot [172aa] mouse double minute 2 homolog isoform MDM2d
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             3.0         15           1
 C cysteine            3.8         19           2
 D aspartate           7.2         36           2
 E glutamate          11.3         56           2
 F phenylalanine       2.2         11           1
 G glycine             4.2         21           2
 H histidine           1.8          9           1
 I isoleucine          4.0         20           2
 K lysine              6.2         31           2
 L leucine             7.2         36           3
 M methionine          1.8          9           1
 N asparagine          3.6         18           1
 P proline             4.6         23           2
 Q glutamine           5.6         28           2
 R arginine            4.6         23           3
 S serine             13.5         67           4
 T threonine           5.0         25           2
 V valine              6.4         32           3
 W tryptophan          0.8          4           1
 Y tyrosine            2.8         14           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   mouse double minute 2 homolog isoform MDM2 
MDM2                  0.884   mouse double minute 2 homolog isoform MDM2f 
MDM2                  0.863   mouse double minute 2 homolog isoform MDM2g 
MDM2                  0.679   mouse double minute 2 homolog isoform MDM2h 
MDM2                  0.480   mouse double minute 2 homolog isoform MDM2i 
MDM2                  0.332   mouse double minute 2 homolog isoform MDM2a 
MDM2                  0.287   mouse double minute 2 homolog isoform MDM2d 
MDM4                  0.225   mouse double minute 4 homolog 
MDM2                  0.182   mouse double minute 2 homolog isoform MDM2e 
MDM2                  0.156   mouse double minute 2 homolog isoform MDM2b 
DSPP                  0.036   dentin sialophosphoprotein preproprotein 
SPARCL1               0.021   SPARC-like 1 
SPARCL1               0.021   SPARC-like 1 
RNF219                0.018   ring finger protein 219 
NEURL                 0.017   neuralized-like 
EIF5B                 0.017   eukaryotic translation initiation factor 5B 
YTHDC1                0.017   splicing factor YT521-B isoform 2 
YTHDC1                0.017   splicing factor YT521-B isoform 1 
BIRC3                 0.016   baculoviral IAP repeat-containing protein 3 
BIRC3                 0.016   baculoviral IAP repeat-containing protein 3 
CYLC1                 0.015   cylicin, basic protein of sperm head cytoskeleton 1...
ACRC                  0.015   ACRC protein 
ANKRD36B              0.015   ankyrin repeat domain 36B 
NEURL1B               0.014   neuralized homolog 1B 
DMP1                  0.014   dentin matrix acidic phosphoprotein 1 isoform 1 precu...
DMP1                  0.014   dentin matrix acidic phosphoprotein 1 isoform 2 pre...
LOC100133923          0.014   PREDICTED: similar to UPF0634 protein C 
RNF157                0.014   ring finger protein 157 
MYLIP                 0.014   myosin regulatory light chain interacting protein [H...
TSR1                  0.014   TSR1, 20S rRNA accumulation 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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