Guide to the Human Genome
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Name: MDM2 Sequence: fasta or formatted (111aa) NCBI GI: 89993692
Description:

mouse double minute 2 homolog isoform MDM2b

Referenced in:

p53 Pathway
Ubiquitin and Related Protein Modifications

Other entries for this name:
alt prot [452aa] mouse double minute 2 homolog isoform MDM2f
alt prot [444aa] mouse double minute 2 homolog isoform MDM2g
alt prot [442aa] mouse double minute 2 homolog isoform MDM2h
alt prot [295aa] mouse double minute 2 homolog isoform MDM2i
alt prot [497aa] mouse double minute 2 homolog isoform MDM2
alt prot [249aa] mouse double minute 2 homolog isoform MDM2a
alt prot [179aa] mouse double minute 2 homolog isoform MDM2e
alt prot [172aa] mouse double minute 2 homolog isoform MDM2d
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             3.6          4           1
 C cysteine            2.7          3           1
 D aspartate           4.5          5           1
 E glutamate           4.5          5           1
 F phenylalanine       1.8          2           1
 G glycine             3.6          4           1
 H histidine           0.9          1           1
 I isoleucine          6.3          7           1
 K lysine              6.3          7           1
 L leucine            12.6         14           3
 M methionine          4.5          5           1
 N asparagine          4.5          5           1
 P proline             4.5          5           1
 Q glutamine           6.3          7           2
 R arginine            4.5          5           1
 S serine              7.2          8           1
 T threonine           8.1          9           2
 V valine              7.2          8           1
 W tryptophan          0.0          0           0
 Y tyrosine            6.3          7           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   mouse double minute 2 homolog isoform MDM2b 
MDM2                  0.773   mouse double minute 2 homolog isoform MDM2h 
MDM2                  0.773   mouse double minute 2 homolog isoform MDM2e 
MDM2                  0.773   mouse double minute 2 homolog isoform MDM2d 
MDM2                  0.773   mouse double minute 2 homolog isoform MDM2a 
MDM2                  0.773   mouse double minute 2 homolog isoform MDM2 
MDM2                  0.717   mouse double minute 2 homolog isoform MDM2g 
MDM2                  0.465   mouse double minute 2 homolog isoform MDM2f 
MDM2                  0.404   mouse double minute 2 homolog isoform MDM2i 
MDM4                  0.242   mouse double minute 4 homolog 
DSC3                  0.030   desmocollin 3 isoform Dsc3b preproprotein 
DSC3                  0.030   desmocollin 3 isoform Dsc3a preproprotein 
KDM2B                 0.015   F-box and leucine-rich repeat protein 10 isoform a [...
KDM2B                 0.015   F-box and leucine-rich repeat protein 10 isoform b [...
PALB2                 0.010   partner and localizer of BRCA2 
AK5                   0.010   adenylate kinase 5 isoform 1 
AK5                   0.010   adenylate kinase 5 isoform 2 
KIAA1731              0.010   hypothetical protein LOC85459 
PHF14                 0.005   PHD finger protein 14 isoform 2 
PHF14                 0.005   PHD finger protein 14 isoform 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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