Guide to the Human Genome
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Name: MDM2 Sequence: fasta or formatted (442aa) NCBI GI: 223890205
Description:

mouse double minute 2 homolog isoform MDM2h

Referenced in:

p53 Pathway
Ubiquitin and Related Protein Modifications

Other entries for this name:
alt prot [452aa] mouse double minute 2 homolog isoform MDM2f
alt prot [444aa] mouse double minute 2 homolog isoform MDM2g
alt prot [295aa] mouse double minute 2 homolog isoform MDM2i
alt prot [497aa] mouse double minute 2 homolog isoform MDM2
alt prot [249aa] mouse double minute 2 homolog isoform MDM2a
alt prot [179aa] mouse double minute 2 homolog isoform MDM2e
alt prot [111aa] mouse double minute 2 homolog isoform MDM2b
alt prot [172aa] mouse double minute 2 homolog isoform MDM2d
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             3.2         14           1
 C cysteine            4.1         18           2
 D aspartate           7.5         33           2
 E glutamate          11.1         49           2
 F phenylalanine       2.5         11           1
 G glycine             4.1         18           1
 H histidine           1.6          7           1
 I isoleucine          4.3         19           2
 K lysine              6.6         29           2
 L leucine             7.2         32           3
 M methionine          2.0          9           1
 N asparagine          3.8         17           1
 P proline             4.8         21           2
 Q glutamine           5.7         25           2
 R arginine            4.1         18           1
 S serine             12.0         53           4
 T threonine           5.0         22           2
 V valine              6.6         29           3
 W tryptophan          0.9          4           1
 Y tyrosine            3.2         14           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   mouse double minute 2 homolog isoform MDM2h 
MDM2                  0.957   mouse double minute 2 homolog isoform MDM2 
MDM2                  0.844   mouse double minute 2 homolog isoform MDM2f 
MDM2                  0.594   mouse double minute 2 homolog isoform MDM2g 
MDM2                  0.538   mouse double minute 2 homolog isoform MDM2i 
MDM2                  0.253   mouse double minute 2 homolog isoform MDM2a 
MDM2                  0.249   mouse double minute 2 homolog isoform MDM2d 
MDM4                  0.237   mouse double minute 4 homolog 
MDM2                  0.204   mouse double minute 2 homolog isoform MDM2e 
MDM2                  0.175   mouse double minute 2 homolog isoform MDM2b 
DSPP                  0.032   dentin sialophosphoprotein preproprotein 
NEURL                 0.019   neuralized-like 
BIRC3                 0.018   baculoviral IAP repeat-containing protein 3 
BIRC3                 0.018   baculoviral IAP repeat-containing protein 3 
EIF5B                 0.018   eukaryotic translation initiation factor 5B 
RNF219                0.017   ring finger protein 219 
NEURL1B               0.016   neuralized homolog 1B 
RNF157                0.016   ring finger protein 157 
MYLIP                 0.016   myosin regulatory light chain interacting protein [H...
TSR1                  0.016   TSR1, 20S rRNA accumulation 
LEO1                  0.016   Leo1, Paf1/RNA polymerase II complex component, homo...
BIRC2                 0.015   baculoviral IAP repeat-containing protein 2 
SETD1B                0.015   SET domain containing 1B 
CFDP1                 0.015   craniofacial development protein 1 
RNF34                 0.014   ring finger protein 34 isoform 1 
RNF34                 0.014   ring finger protein 34 isoform 2 
CYLC1                 0.014   cylicin, basic protein of sperm head cytoskeleton 1...
MUL1                  0.014   mitochondrial ubiquitin ligase activator of NFKB 1 ...
XIAP                  0.014   baculoviral IAP repeat-containing protein 4 
MYST3                 0.013   MYST histone acetyltransferase (monocytic leukemia)...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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