Guide to the Human Genome
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Name: MDM2 Sequence: fasta or formatted (249aa) NCBI GI: 89993690
Description:

mouse double minute 2 homolog isoform MDM2a

Referenced in:

p53 Pathway
Ubiquitin and Related Protein Modifications

Other entries for this name:
alt prot [452aa] mouse double minute 2 homolog isoform MDM2f
alt prot [444aa] mouse double minute 2 homolog isoform MDM2g
alt prot [442aa] mouse double minute 2 homolog isoform MDM2h
alt prot [295aa] mouse double minute 2 homolog isoform MDM2i
alt prot [497aa] mouse double minute 2 homolog isoform MDM2
alt prot [179aa] mouse double minute 2 homolog isoform MDM2e
alt prot [111aa] mouse double minute 2 homolog isoform MDM2b
alt prot [172aa] mouse double minute 2 homolog isoform MDM2d
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             2.8          7           1
 C cysteine            4.0         10           1
 D aspartate           3.6          9           1
 E glutamate           7.2         18           2
 F phenylalanine       2.0          5           1
 G glycine             4.8         12           2
 H histidine           2.4          6           1
 I isoleucine          4.4         11           1
 K lysine              7.6         19           2
 L leucine             8.8         22           3
 M methionine          3.2          8           1
 N asparagine          3.6          9           1
 P proline             5.6         14           1
 Q glutamine           6.4         16           2
 R arginine            5.6         14           3
 S serine             10.0         25           3
 T threonine           6.4         16           2
 V valine              8.0         20           3
 W tryptophan          0.0          0           0
 Y tyrosine            3.2          8           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   mouse double minute 2 homolog isoform MDM2a 
MDM2                  0.681   mouse double minute 2 homolog isoform MDM2 
MDM2                  0.658   mouse double minute 2 homolog isoform MDM2g 
MDM2                  0.589   mouse double minute 2 homolog isoform MDM2d 
MDM2                  0.463   mouse double minute 2 homolog isoform MDM2h 
MDM2                  0.443   mouse double minute 2 homolog isoform MDM2f 
MDM2                  0.374   mouse double minute 2 homolog isoform MDM2e 
MDM2                  0.319   mouse double minute 2 homolog isoform MDM2b 
MDM2                  0.299   mouse double minute 2 homolog isoform MDM2i 
MDM4                  0.163   mouse double minute 4 homolog 
NEURL                 0.035   neuralized-like 
NEURL1B               0.029   neuralized homolog 1B 
RNF157                0.027   ring finger protein 157 
MYLIP                 0.025   myosin regulatory light chain interacting protein [H...
BIRC3                 0.023   baculoviral IAP repeat-containing protein 3 
BIRC3                 0.023   baculoviral IAP repeat-containing protein 3 
MGRN1                 0.023   mahogunin, ring finger 1 isoform 4 
MGRN1                 0.023   mahogunin, ring finger 1 isoform 2 
BIRC7                 0.023   livin inhibitor of apoptosis isoform beta 
MUL1                  0.023   mitochondrial ubiquitin ligase activator of NFKB 1 ...
RNF34                 0.021   ring finger protein 34 isoform 1 
RNF34                 0.021   ring finger protein 34 isoform 2 
MGRN1                 0.021   mahogunin, ring finger 1 isoform 3 
MGRN1                 0.021   mahogunin, ring finger 1 isoform 1 
LRSAM1                0.021   leucine rich repeat and sterile alpha motif containi...
LRSAM1                0.021   leucine rich repeat and sterile alpha motif containi...
LRSAM1                0.021   leucine rich repeat and sterile alpha motif containi...
BIRC2                 0.019   baculoviral IAP repeat-containing protein 2 
XIAP                  0.019   baculoviral IAP repeat-containing protein 4 
MIB1                  0.019   mindbomb homolog 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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