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Search of human proteins with 223633935
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223633935 hypothetical protein LOC254427 [Homo sapiens]
(435 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223633935 hypothetical protein LOC254427 [Homo sapiens] 885 0.0
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 73 4e-13
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 68 1e-11
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 67 2e-11
gi|110832843 TBP-associated factor 4 [Homo sapiens] 67 2e-11
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 63 5e-10
gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens] 60 4e-09
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 60 5e-09
gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens] 59 7e-09
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 59 1e-08
gi|19913398 smoothelin isoform a [Homo sapiens] 58 1e-08
gi|19913396 smoothelin isoform b [Homo sapiens] 58 2e-08
gi|19913394 smoothelin isoform c [Homo sapiens] 58 2e-08
gi|237757308 synaptojanin 1 isoform b [Homo sapiens] 57 3e-08
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 57 3e-08
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 57 4e-08
gi|145275189 specifically androgen-regulated protein isoform 1 [... 56 6e-08
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens] 56 7e-08
gi|163965366 nascent polypeptide-associated complex alpha subuni... 56 7e-08
gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 55 1e-07
gi|237757310 synaptojanin 1 isoform a [Homo sapiens] 55 1e-07
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 55 1e-07
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 55 1e-07
gi|18079216 CASK interacting protein 1 [Homo sapiens] 55 1e-07
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 55 1e-07
gi|169217659 PREDICTED: similar to ectonucleotide pyrophosphatas... 55 2e-07
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 55 2e-07
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 55 2e-07
gi|169167316 PREDICTED: similar to ectonucleotide pyrophosphatas... 55 2e-07
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 55 2e-07
>gi|223633935 hypothetical protein LOC254427 [Homo sapiens]
Length = 435
Score = 885 bits (2286), Expect = 0.0
Identities = 435/435 (100%), Positives = 435/435 (100%)
Query: 1 MPVTHRKSDASDMNSDTSPSCRLRAFSRGGSLESRSSSSRSRSFTLDDESLKYLTHEEKD 60
MPVTHRKSDASDMNSDTSPSCRLRAFSRGGSLESRSSSSRSRSFTLDDESLKYLTHEEKD
Sbjct: 1 MPVTHRKSDASDMNSDTSPSCRLRAFSRGGSLESRSSSSRSRSFTLDDESLKYLTHEEKD 60
Query: 61 VLLFFEETIDSLDEDFEEPVLCDGGVCCLCSPSLEESTSSPSEPEDVIDLVQPAPGAGEA 120
VLLFFEETIDSLDEDFEEPVLCDGGVCCLCSPSLEESTSSPSEPEDVIDLVQPAPGAGEA
Sbjct: 61 VLLFFEETIDSLDEDFEEPVLCDGGVCCLCSPSLEESTSSPSEPEDVIDLVQPAPGAGEA 120
Query: 121 EGLPEGTQAAGPAPAGKEHRKQDAETPPPPDPPAPETLLAPPPLPSTPDPPRRELRAPSP 180
EGLPEGTQAAGPAPAGKEHRKQDAETPPPPDPPAPETLLAPPPLPSTPDPPRRELRAPSP
Sbjct: 121 EGLPEGTQAAGPAPAGKEHRKQDAETPPPPDPPAPETLLAPPPLPSTPDPPRRELRAPSP 180
Query: 181 PVEHPRLLRSVPTPLVMAQKISERMAGNEALSPTSPFREGRPGEWRTPAARGPRSGDPGP 240
PVEHPRLLRSVPTPLVMAQKISERMAGNEALSPTSPFREGRPGEWRTPAARGPRSGDPGP
Sbjct: 181 PVEHPRLLRSVPTPLVMAQKISERMAGNEALSPTSPFREGRPGEWRTPAARGPRSGDPGP 240
Query: 241 GPSHPAQPKAPRFPSNIIVTNGAAREPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAAG 300
GPSHPAQPKAPRFPSNIIVTNGAAREPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAAG
Sbjct: 241 GPSHPAQPKAPRFPSNIIVTNGAAREPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAAG 300
Query: 301 DAGEGAPGGGSSPERVARGRGLPGPAESLRAGGQAPRGPALANGFPSAHEALKSAPSSFA 360
DAGEGAPGGGSSPERVARGRGLPGPAESLRAGGQAPRGPALANGFPSAHEALKSAPSSFA
Sbjct: 301 DAGEGAPGGGSSPERVARGRGLPGPAESLRAGGQAPRGPALANGFPSAHEALKSAPSSFA 360
Query: 361 PAGKSLCFRPGPALPSTRARQSFPGPRQPNGAQDWRRADSLPRPQGITVQFAGRGSSEEA 420
PAGKSLCFRPGPALPSTRARQSFPGPRQPNGAQDWRRADSLPRPQGITVQFAGRGSSEEA
Sbjct: 361 PAGKSLCFRPGPALPSTRARQSFPGPRQPNGAQDWRRADSLPRPQGITVQFAGRGSSEEA 420
Query: 421 RREALRKLGLLRESS 435
RREALRKLGLLRESS
Sbjct: 421 RREALRKLGLLRESS 435
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 73.2 bits (178), Expect = 4e-13
Identities = 100/364 (27%), Positives = 127/364 (34%), Gaps = 65/364 (17%)
Query: 74 EDFEEPVLCDGGVCCLCSPSLEESTSSPS------EPEDVIDLVQPAPGAGEAEGLPEGT 127
+D P + G C +C L ++ P EP D+ D+V P G P+G
Sbjct: 73 KDCLSPEIPFGECCPICPTDLATASGQPGPKGQKGEPGDIKDIVGPKGPPG-----PQG- 126
Query: 128 QAAGPAPAGKEHRKQDAETPPPPDPPAPETLLAPPPLPSTPDPPRRELRAPSPPVEHPRL 187
PAG++ + D P P P P P PP P P P L
Sbjct: 127 ------PAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPP-----GPPGPPGPPGL 175
Query: 188 LRSVPTPLVMAQKISERMAGNE------ALSPTSPFREGRPGEWRTPAARG--PRSGDPG 239
+ MA E+ G + + P P G PG P +G G+PG
Sbjct: 176 GGNFAAQ--MAGGFDEKAGGAQLGVMQGPMGPMGP--RGPPGPAGAPGPQGFQGNPGEPG 231
Query: 240 -PGPSHPAQPKAPRFPSNIIVTNGAAREPRRTLSRAAVSVQERR----AQVLATIHGHAG 294
PG S P P+ P P +G A +P + R Q R L + GH G
Sbjct: 232 EPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRG 291
Query: 295 AFP----AAGDAG-------EGAPGGGSSPERVARGRGLPGPAESLRAGGQAPRGPALAN 343
+P A G+AG G+PG SP + RGLPG G P G A A
Sbjct: 292 -YPGLDGAKGEAGAPGVKGESGSPGENGSPGPMG-PRGLPG-----ERGRTGPAGAAGAR 344
Query: 344 GFPSAHEALKSAPSSFAPAGKSLCFRPG-PALPSTRARQSFPGPRQPNGAQDWRRADSLP 402
G P PAG PG P P + G R P GAQ R P
Sbjct: 345 G-NDGQPGPAGPPGPVGPAG-----GPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTP 398
Query: 403 RPQG 406
G
Sbjct: 399 GSPG 402
Score = 57.4 bits (137), Expect = 3e-08
Identities = 91/320 (28%), Positives = 110/320 (34%), Gaps = 48/320 (15%)
Query: 116 GAGEAEGLPEGTQAAGPAPAGKEHRKQDAETPPPPDPPAPETLLAPPPLPSTPDPPRRE- 174
GA A+G P T P AG+ P PP PP P P PP R
Sbjct: 885 GARGAQGPPGAT--GFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAG 942
Query: 175 ---LRAPS-PPVEH-------PRLLRSVPTPLVMA-QKISERMAGN--EALSPTSPFREG 220
L+ P+ PP E P P P +A Q+ + G E P P G
Sbjct: 943 EPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSG 1002
Query: 221 RPGEWRTPAARGPRSGDPGPGPSHPAQPKAPRFPSNIIVTNGAAREPRRTLSRAAVSVQE 280
PG+ P A G R PGP P P + GA P R A V+
Sbjct: 1003 EPGKQGAPGASGDRGP---PGPVGPPGLTGPAGEPGREGSPGADGPPGRD---GAAGVKG 1056
Query: 281 RRAQVLAT----------IHGHAGAFPAAGDAGEGAPGGGSSPERVARGRGLPGP----A 326
R + A G AG GD GE G P A RG+ GP
Sbjct: 1057 DRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRG 1116
Query: 327 ESLRAGGQAPRGPALANGFPSAHEALKSAPSSFAPAGKSLCFRPGPALPSTRARQSFPGP 386
+ AG RG GF L+ P P+G GPA PS + PGP
Sbjct: 1117 DKGEAGEPGERGLKGHRGF----TGLQGLPGPPGPSGDQ--GASGPAGPS--GPRGPPGP 1168
Query: 387 RQPNGAQDWRRADSLPRPQG 406
P+G A+ +P P G
Sbjct: 1169 VGPSGKDG---ANGIPGPIG 1185
Score = 50.8 bits (120), Expect = 2e-06
Identities = 84/307 (27%), Positives = 103/307 (33%), Gaps = 46/307 (14%)
Query: 115 PGAGEAEGLP--EG-TQAAGP-APAGKEHRKQDAETPPP------PDPPAPETLLAPPPL 164
PGA GLP +G T AAGP PAG + + P P P PP P P
Sbjct: 623 PGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGD 682
Query: 165 PSTPDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGNEAL--SPTSPFREGRP 222
P A +P + PR R P ++ + G L +P + +G
Sbjct: 683 QGVPG------EAGAPGLVGPRGERGFPGE--RGSPGAQGLQGPRGLPGTPGTDGPKGAS 734
Query: 223 GEWRTPAARGPRSGDPGPGPSHPAQPKAPRFPSNIIVTNGAAREPRRTLSRAAVSVQERR 282
G P A+GP PG A P+ + G P + R
Sbjct: 735 GPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGP---- 790
Query: 283 AQVLATIHGHAGAFPAAGDAGEGAPGGGSSPERVARGRGLPGPAESLRAGGQAPRGPALA 342
G AGA G+ G P G A RG PG G P GPA
Sbjct: 791 ----IGPPGPAGANGEKGEVGPPGPAGS------AGARGAPG-----ERGETGPPGPAGF 835
Query: 343 NGFPSAHEALKSAPSSFAPAG-KSLCFRPGPALPSTRARQSFPGPRQPNGAQDWRRADSL 401
G P A + A AG K PGP PS PGP+ P G + A
Sbjct: 836 AGPPGA-DGQPGAKGEQGEAGQKGDAGAPGPQGPS-----GAPGPQGPTGVTGPKGARGA 889
Query: 402 PRPQGIT 408
P G T
Sbjct: 890 QGPPGAT 896
Score = 50.4 bits (119), Expect = 3e-06
Identities = 98/347 (28%), Positives = 114/347 (32%), Gaps = 80/347 (23%)
Query: 114 APGAGEAEGLPEGTQAAG-PAPAGKEHRKQDAETPPPPDPPAPETLLAP-PPLPSTPDP- 170
A G +G+P +AG P AG P P PP P+ P P T +P
Sbjct: 406 ASGNPGTDGIPGAKGSAGAPGIAGAPG------FPGPRGPPGPQGATGPLGPKGQTGEPG 459
Query: 171 ---------------PRRELRAPSPPVEH-PRLLRSVPTPLVMAQKISERMA-GNEALSP 213
P AP P E R R P + ER A GN
Sbjct: 460 IAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGF-- 517
Query: 214 TSPFREGRPGEWRTPAARGPR--------SGDPGPGPSHPAQPKAPRF--------PSNI 257
P ++G G P RGP +GDPG P P P A P
Sbjct: 518 --PGQDGLAGPKGAPGERGPSGLAGPKGANGDPGR-PGEPGLPGARGLTGRPGDAGPQGK 574
Query: 258 IVTNGAAREPRRTLSRAAVSVQERRAQV-LATIHGHAGAFPAAGDAGE-GAPGGGSSPER 315
+ +GA E R Q R Q + G GA G AGE G PG
Sbjct: 575 VGPSGAPGEDGRP---GPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGL--- 628
Query: 316 VARGRGLPGP-AESLRAGGQAPRGPALANGF-----PSAHEALKSAPSSFAPAGKSLCFR 369
RGLPG E+ AG P GPA G PS + L P GK
Sbjct: 629 ----RGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGK----- 679
Query: 370 PG----------PALPSTRARQSFPGPRQPNGAQDWRRADSLPRPQG 406
PG P L R + FPG R GAQ + LP G
Sbjct: 680 PGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPG 726
Score = 42.7 bits (99), Expect = 6e-04
Identities = 87/321 (27%), Positives = 103/321 (32%), Gaps = 69/321 (21%)
Query: 112 QPAPG-AGE-----AEGLPEGTQAAGP-----APAGKEHRKQDAETPPP--PDPPAPETL 158
Q APG AGE A G P G GP AP + QD P P P L
Sbjct: 479 QGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGL 538
Query: 159 LAPPPLPSTPDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGNEALSPTSPFR 218
P P P P + R L P K+ A P
Sbjct: 539 AGPKGANGDPGRPGE------PGLPGARGLTGRPGDAGPQGKVGPSGA---------PGE 583
Query: 219 EGRPGEWRTPAARGPRSGDPG----PGPSHPAQPKAPRFPSNIIVTNGAAREPRRTLSRA 274
+GRPG P +G R G PG PGP GA EP + +
Sbjct: 584 DGRPG---PPGPQGAR-GQPGVMGFPGP------------------KGANGEPGKAGEKG 621
Query: 275 AVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPGGGSSPERVARG----RGLPG----PA 326
A L + G G AAG G P G E+ A G +GLPG P
Sbjct: 622 LPG-----APGLRGLPGKDGETGAAGPPGPAGP-AGERGEQGAPGPSGFQGLPGPPGPPG 675
Query: 327 ESLRAGGQAPRGPALANGFPSAHEALKSAPSSFAPAGKSLCFRPG-PALPSTRARQSFPG 385
E + G Q G A A G +P + L G P P T + G
Sbjct: 676 EGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASG 735
Query: 386 PRQPNGAQDWRRADSLPRPQG 406
P P GAQ +P +G
Sbjct: 736 PAGPPGAQGPPGLQGMPGERG 756
Score = 42.4 bits (98), Expect = 8e-04
Identities = 47/180 (26%), Positives = 62/180 (34%), Gaps = 20/180 (11%)
Query: 216 PFREGRPGEWRTPAARGPRSGDPGPGPSHPAQPKAPRFPSNIIVTNGA--AREPRRTLSR 273
P +G+PG G + PGP P+ P+ P+ + GA A+ P
Sbjct: 839 PGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP-----P 893
Query: 274 AAVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPGGGSSPERVARGRGLPGPAESLRAGG 333
A +V G G+ G G P G P+ G PG A G
Sbjct: 894 GATGFPGAAGRV-----GPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAG--EPGL 946
Query: 334 QAPRGPALANGFP--SAHEALKSAPSSFAPAGKSLCFRPGPALPSTRARQSFPGPRQPNG 391
Q P GP G P + P AG+ R LP R + FPG P+G
Sbjct: 947 QGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQ----RGIVGLPGQRGERGFPGLPGPSG 1002
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 68.2 bits (165), Expect = 1e-11
Identities = 100/334 (29%), Positives = 122/334 (36%), Gaps = 59/334 (17%)
Query: 105 EDVI-DLVQPAPGAGEAEG-----LPEGTQA-AGPAPAGKEHRKQDAETPP-----PPDP 152
+DVI D + PGA EG P+G+++ G E K D T P P P
Sbjct: 71 DDVICDETKNCPGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGD--TGPRGPRGPAGP 128
Query: 153 PAPETLLAPPPLPSTPDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGNEALS 212
P + + P LP P PP P PP L P + + G
Sbjct: 129 PGRDGIPGQPGLPGPPGPP----GPPGPPG-----LGGNFAPQLSYGYDEKSTGGISVPG 179
Query: 213 PTSPF-REGRPGEWRTPAARGPRS-----GDPG-PGPSHPAQPKAPRFPSNIIVTNGAAR 265
P P G PG P A GP+ G+PG PG S P P+ P P +G A
Sbjct: 180 PMGPSGPRGLPG---PPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAG 236
Query: 266 EPRRTLSRAAVSVQERR----AQVLATIHGH---AGAFPAAGDAGEGAPGG--GSSPERV 316
+P R R Q R L + GH +G A GDAG P G GS E
Sbjct: 237 KPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENG 296
Query: 317 ARG----RGLPGPAESLRAGGQAPRGPALANGFPSAHEALKSAPSSFAPAGKSLCFRPGP 372
A G RGLPG G GPA A G A A P PAG P
Sbjct: 297 APGQMGPRGLPG-----ERGRPGAPGPAGARGNDGATGA-AGPPGPTGPAGP-------P 343
Query: 373 ALPSTRARQSFPGPRQPNGAQDWRRADSLPRPQG 406
P + GP+ P G++ + P P G
Sbjct: 344 GFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPG 377
Score = 62.4 bits (150), Expect = 8e-10
Identities = 99/321 (30%), Positives = 116/321 (36%), Gaps = 58/321 (18%)
Query: 114 APGAGEAEGLP-EGTQAAGPAPAGKEHRKQDAETPPPPDPPAPETLLAPPPLPST----- 167
APG GLP E + P PAG PP P P PP P
Sbjct: 297 APGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPA---GPPGFPGAVGAKG 353
Query: 168 ---PDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGNEALS--PTSPFREGRP 222
P PR E P+ +R P P A AGN P + G P
Sbjct: 354 EAGPQGPRGS--------EGPQGVRGEPGPPGPAGAAGP--AGNPGADGQPGAKGANGAP 403
Query: 223 GEWRTPA---ARGPRSGDPGPG-PSHP----AQPKAPRFPSNIIVTNGAAREPRRTLSRA 274
G P ARGP SG GPG P P +P AP + GA EP +
Sbjct: 404 GIAGAPGFPGARGP-SGPQGPGGPPGPKGNSGEPGAPGSKGD----TGAKGEPGPVGVQG 458
Query: 275 AVSVQERRAQVLATIHGHAGAFPAAGDAGE-GAPG--------GGSSPERVARGRGLPGP 325
+ A G G G GE G PG G + P+ A RG PGP
Sbjct: 459 PPGPAGEEGKRGA--RGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGP 516
Query: 326 AESLRAGGQAPRGPALANGFPSAHEALKSAPSSFAPAGKSLCFRPGPALPSTRARQSFPG 385
A + G+A R P A G P A + L +P S P GK+ PGPA R PG
Sbjct: 517 AGPKGSPGEAGR-PGEA-GLPGA-KGLTGSPGSPGPDGKT--GPPGPAGQDGR-----PG 566
Query: 386 PRQPNGAQDWRRADSLPRPQG 406
P P GA+ P P+G
Sbjct: 567 PPGPPGARGQAGVMGFPGPKG 587
Score = 58.2 bits (139), Expect = 1e-08
Identities = 96/352 (27%), Positives = 112/352 (31%), Gaps = 85/352 (24%)
Query: 114 APGA-----GEAEGLPEGTQAAGPAPAGKEHRKQDAETPPPPDPPAPETLLAPPPLPSTP 168
APG+ + E P G Q P PAG+E ++ P P P P P S
Sbjct: 438 APGSKGDTGAKGEPGPVGVQGP-PGPAGEEGKRGARGEPGPTGLPGPPGERGGPG--SRG 494
Query: 169 DPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGNEALSPTSPFREGRPGEWRTP 228
P + P P ER + A SP GRPGE P
Sbjct: 495 FPGADGVAGPKGPA-------------------GERGSPGPAGPKGSPGEAGRPGEAGLP 535
Query: 229 AARG--PRSGDPGP----GPSHPA----QPKAPRFPS--------NIIVTNGAAREPRRT 270
A+G G PGP GP PA +P P P GAA EP +
Sbjct: 536 GAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKA 595
Query: 271 LSRA-------------------------AVSVQERRAQVLATIHGHAGAFPAAGDAGE- 304
R A ER Q A G G AG GE
Sbjct: 596 GERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEA 655
Query: 305 ------GAPG--GGSSPERVARGRGLPGPAESLRAGGQAPRGPALANGFPSAHEALKSAP 356
G PG G P RG PG E G P GP ANG P A A
Sbjct: 656 GKPGEQGVPGDLGAPGPSGARGERGFPG--ERGVQGPPGPAGPRGANGAPGNDGAKGDAG 713
Query: 357 SSFAPAGKSLCFRPG-PALPSTRARQSFPGPRQPNGAQDWRRADSLPRPQGI 407
+ AP + PG +P R PGP+ G + AD P G+
Sbjct: 714 APGAPGSQG---APGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGV 762
Score = 52.0 bits (123), Expect = 1e-06
Identities = 82/289 (28%), Positives = 95/289 (32%), Gaps = 60/289 (20%)
Query: 147 PPPPDPPAPETLLAPPPLPSTPD------------PPRR-----ELRAPSPPVEH----P 185
P PP P P+ PP P P PP + E P P E P
Sbjct: 190 PGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGP 249
Query: 186 RLLRSVP-TPLVMAQKISERMAGNEALS----PTSPFRE-GRPGEWRTPAARGPRSGDPG 239
+ R +P T + K +G + P P E G PGE P GPR G PG
Sbjct: 250 QGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPR-GLPG 308
Query: 240 PGPSHPAQPKAPRFPSNIIVTNGAAREPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAA 299
P P N T GAA P T A G GA A
Sbjct: 309 ER-GRPGAPGPAGARGNDGAT-GAAGPPGPTGP--------------AGPPGFPGAVGAK 352
Query: 300 GDAGEGAPGGGSSPERVARGRGLPGPAESLRAGGQAPRGPALANGFPSAHEALKSAPSSF 359
G+AG P G P+ V G PGP AG P G A+G P A K A +
Sbjct: 353 GEAGPQGPRGSEGPQGVRGEPGPPGP-----AGAAGPAGNPGADGQPGA----KGANGAP 403
Query: 360 APAGKSLCFRPGPALPSTRARQSFPGPRQPNGAQDWRRADSLPRPQGIT 408
AG P P R GP P G + P +G T
Sbjct: 404 GIAG-------APGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDT 445
Score = 50.1 bits (118), Expect = 4e-06
Identities = 95/329 (28%), Positives = 115/329 (34%), Gaps = 81/329 (24%)
Query: 115 PGAGEAEGLPEGTQAAGPAPAGKEHRKQDAETPPPPDPPAPETLLAPPP-------LPST 167
PG G+P A GPA GK+ + A+ PP P PA E P LP
Sbjct: 592 PGKAGERGVPGPPGAVGPA--GKDG-EAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGP 648
Query: 168 PDPPRR-----------ELRAPSPPVEH-------PRLLRSVPTPLVMAQKISERMAGNE 209
PP +L AP P R ++ P P + + GN+
Sbjct: 649 AGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPA--GPRGANGAPGND 706
Query: 210 -----ALSPTSPFREGRPGEWRTPAARGPRSGDPGP-GPSHPAQPKAPRFPSNIIVTNGA 263
A +P +P +G PG P RG +G PGP G A PK GA
Sbjct: 707 GAKGDAGAPGAPGSQGAPGLQGMPGERG-AAGLPGPKGDRGDAGPK------------GA 753
Query: 264 AREPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPGGGSSPERVARG---- 319
P + R L G G A GD GE P G + P ARG
Sbjct: 754 DGSPGKDGVRG-----------LTGPIGPPGPAGAPGDKGESGPSGPAGPTG-ARGAPGD 801
Query: 320 RGLPGPAESLRAGGQAPRGPALANGFPSAHEALKSAPSSFAPAGKSLCFRPGPALPSTRA 379
RG PGP G GP A+G P A K P G + PGPA P+
Sbjct: 802 RGEPGP-----PGPAGFAGPPGADGQPGA----KGEPGDAGAKGDA--GPPGPAGPA--- 847
Query: 380 RQSFPGPRQPNGAQDWRRADSLPRPQGIT 408
PGP GA + A P G T
Sbjct: 848 --GPPGPIGNVGAPGAKGARGSAGPPGAT 874
Score = 50.1 bits (118), Expect = 4e-06
Identities = 77/280 (27%), Positives = 95/280 (33%), Gaps = 25/280 (8%)
Query: 116 GAGEAEGLPEGTQAAG-PAPAGKEHRKQDAETPPPPDPPAPETLLAP--PPLPSTPDPPR 172
GA +G+P AAG P P G P L P PP P+ +
Sbjct: 722 GAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDK 781
Query: 173 RELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGNEALSPTSPFREGRPGEWRTPAARG 232
E PS P P R P E A P +G+PG P G
Sbjct: 782 GE-SGPSGPAG-PTGARGAPGDR------GEPGPPGPAGFAGPPGADGQPGAKGEPGDAG 833
Query: 233 PRSGDPGPGPSHPAQPKAPRFPSNIIVTNGAAREPRRTLSRAAVSVQERRAQVLATIHGH 292
+ PGP+ PA P P + N A + A S A G
Sbjct: 834 AKGDAGPPGPAGPAGPPGP-------IGNVGAPGAK----GARGSAGPPGATGFPGAAGR 882
Query: 293 AGAFPAAGDAGEGAPGGGSSPERVARGRGLPGPA-ESLRAGGQAPRGPALANGFPSAHEA 351
G +G+AG P G + E RG GPA G P GPA G P A +
Sbjct: 883 VGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGA-DG 941
Query: 352 LKSAPSSFAPAGKSLCFRPGPALPSTRARQSFPGPRQPNG 391
AP + P G + R LP R + FPG P+G
Sbjct: 942 PAGAPGTPGPQGIA-GQRGVVGLPGQRGERGFPGLPGPSG 980
Score = 48.1 bits (113), Expect = 2e-05
Identities = 88/323 (27%), Positives = 103/323 (31%), Gaps = 38/323 (11%)
Query: 114 APGAGEAEGLPEGTQAAG-PAPAGKEHRKQDAETPPPPDPPAP-----------ETLLAP 161
APGA A G A G P AG+ + PP PP P ET A
Sbjct: 858 APGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAG 917
Query: 162 PPLP-STPDPPRRELRAPSPPVEHPRLLRSVPTPLVMA-QKISERMAGN--EALSPTSPF 217
P P PP SP + P P P +A Q+ + G E P P
Sbjct: 918 RPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPG 977
Query: 218 REGRPGEWRTPAARGPRSGDPGPGPSHPAQPKAPRFPSNIIVTNGAAREPRRTLSRAAVS 277
G PG+ A G R PGP P P S GA P R S A
Sbjct: 978 PSGEPGKQGPSGASGERGP---PGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKG 1034
Query: 278 VQERR-------AQVLATIHGHAGAFPAAGDAGEGAPGGGSSPERVARGRGLPGP----A 326
+ A G G +GD GE P G + P RG GP
Sbjct: 1035 DRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRG 1094
Query: 327 ESLRAGGQAPRGPALANGFPSAH--EALKSAPSSFAPAGKSLCFRP-GP----ALPSTRA 379
+ G Q RG GF +P P+G S P GP P
Sbjct: 1095 DKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDG 1154
Query: 380 RQSFPGPRQPNGAQDWRRADSLP 402
PGP P G + R D+ P
Sbjct: 1155 LNGLPGPIGPPGPRG-RTGDAGP 1176
Score = 32.3 bits (72), Expect = 0.86
Identities = 41/164 (25%), Positives = 52/164 (31%), Gaps = 11/164 (6%)
Query: 92 PSLEESTSSPSEPEDVIDLVQPAPGAGEAEGLP--EGTQAAGPAPAGKEHRKQDAETPPP 149
PS P P L P PG EG P EG+ +P K R + PP
Sbjct: 987 PSGASGERGPPGPMGPPGLAGP-PGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPP 1045
Query: 150 PDPPAPETLLAPPPLPSTPDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGNE 209
P AP P + D P+ PV K G+
Sbjct: 1046 GAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDR 1105
Query: 210 ALSPTSPFR--EGRPGEWRTPAARGPRSGDPGPGPSHPAQPKAP 251
+ F +G PG +P +GP G S PA P+ P
Sbjct: 1106 GIKGHRGFSGLQGPPGPPGSPGEQGP------SGASGPAGPRGP 1143
Score = 32.0 bits (71), Expect = 1.1
Identities = 25/69 (36%), Positives = 27/69 (39%), Gaps = 17/69 (24%)
Query: 114 APGAGEAEGLPEGTQAAGP-APAGKEHRKQDAETPPPPDPPAPETLLAPPPLPST----- 167
APG GLP GP P G R DA PP PP P PP PS
Sbjct: 1149 APGKDGLNGLP------GPIGPPGPRGRTGDAGPVGPPGPPGPP---GPPGPPSAGFDFS 1199
Query: 168 --PDPPRRE 174
P PP+ +
Sbjct: 1200 FLPQPPQEK 1208
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 67.4 bits (163), Expect = 2e-11
Identities = 93/329 (28%), Positives = 115/329 (34%), Gaps = 59/329 (17%)
Query: 103 EPEDVIDLVQPAPGAGEAEGLPEGTQAAGPAPAGKEHRKQDAETPPPPDPPAPETLLAPP 162
EP D+ D+V P G P+G PAG++ + D P P P
Sbjct: 39 EPGDIKDIVGPKGPPG-----PQG-------PAGEQGPRGDRGDKGEKGAPGPRGRDGEP 86
Query: 163 PLPSTPDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGNE------ALSPTSP 216
P P PP P P P L + MA E+ G + + P P
Sbjct: 87 GTPGNPGPP-----GPPGPPGPPGLGGNFAAQ--MAGGFDEKAGGAQLGVMQGPMGPMGP 139
Query: 217 FREGRPGEWRTPAARG--PRSGDPG-PGPSHPAQPKAPRFPSNIIVTNGAAREPRRTLSR 273
G PG P +G G+PG PG S P P+ P P +G A +P + R
Sbjct: 140 --RGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGER 197
Query: 274 AAVSVQERR----AQVLATIHGHAGAFP----AAGDAG-------EGAPGGGSSPERVAR 318
Q R L + GH G +P A G+AG G+PG SP +
Sbjct: 198 GPPGPQGARGFPGTPGLPGVKGHRG-YPGLDGAKGEAGAPGVKGESGSPGENGSPGPMG- 255
Query: 319 GRGLPGPAESLRAGGQAPRGPALANGFPSAHEALKSAPSSFAPAGKSLCFRPG-PALPST 377
RGLPG G P G A A G P PAG PG P P
Sbjct: 256 PRGLPG-----ERGRTGPAGAAGARG-NDGQPGPAGPPGPVGPAG-----GPGFPGAPGA 304
Query: 378 RARQSFPGPRQPNGAQDWRRADSLPRPQG 406
+ G R P GAQ R P G
Sbjct: 305 KGEAGPTGARGPEGAQGPRGEPGTPGSPG 333
Score = 57.4 bits (137), Expect = 3e-08
Identities = 91/320 (28%), Positives = 110/320 (34%), Gaps = 48/320 (15%)
Query: 116 GAGEAEGLPEGTQAAGPAPAGKEHRKQDAETPPPPDPPAPETLLAPPPLPSTPDPPRRE- 174
GA A+G P T P AG+ P PP PP P P PP R
Sbjct: 816 GARGAQGPPGAT--GFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAG 873
Query: 175 ---LRAPS-PPVEH-------PRLLRSVPTPLVMA-QKISERMAGN--EALSPTSPFREG 220
L+ P+ PP E P P P +A Q+ + G E P P G
Sbjct: 874 EPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSG 933
Query: 221 RPGEWRTPAARGPRSGDPGPGPSHPAQPKAPRFPSNIIVTNGAAREPRRTLSRAAVSVQE 280
PG+ P A G R PGP P P + GA P R A V+
Sbjct: 934 EPGKQGAPGASGDRGP---PGPVGPPGLTGPAGEPGREGSPGADGPPGRD---GAAGVKG 987
Query: 281 RRAQVLAT----------IHGHAGAFPAAGDAGEGAPGGGSSPERVARGRGLPGP----A 326
R + A G AG GD GE G P A RG+ GP
Sbjct: 988 DRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRG 1047
Query: 327 ESLRAGGQAPRGPALANGFPSAHEALKSAPSSFAPAGKSLCFRPGPALPSTRARQSFPGP 386
+ AG RG GF L+ P P+G GPA PS + PGP
Sbjct: 1048 DKGEAGEPGERGLKGHRGF----TGLQGLPGPPGPSGDQ--GASGPAGPS--GPRGPPGP 1099
Query: 387 RQPNGAQDWRRADSLPRPQG 406
P+G A+ +P P G
Sbjct: 1100 VGPSGKDG---ANGIPGPIG 1116
Score = 50.8 bits (120), Expect = 2e-06
Identities = 84/307 (27%), Positives = 103/307 (33%), Gaps = 46/307 (14%)
Query: 115 PGAGEAEGLP--EG-TQAAGP-APAGKEHRKQDAETPPP------PDPPAPETLLAPPPL 164
PGA GLP +G T AAGP PAG + + P P P PP P P
Sbjct: 554 PGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGD 613
Query: 165 PSTPDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGNEAL--SPTSPFREGRP 222
P A +P + PR R P ++ + G L +P + +G
Sbjct: 614 QGVPG------EAGAPGLVGPRGERGFPGE--RGSPGAQGLQGPRGLPGTPGTDGPKGAS 665
Query: 223 GEWRTPAARGPRSGDPGPGPSHPAQPKAPRFPSNIIVTNGAAREPRRTLSRAAVSVQERR 282
G P A+GP PG A P+ + G P + R
Sbjct: 666 GPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGP---- 721
Query: 283 AQVLATIHGHAGAFPAAGDAGEGAPGGGSSPERVARGRGLPGPAESLRAGGQAPRGPALA 342
G AGA G+ G P G A RG PG G P GPA
Sbjct: 722 ----IGPPGPAGANGEKGEVGPPGPAGS------AGARGAPG-----ERGETGPPGPAGF 766
Query: 343 NGFPSAHEALKSAPSSFAPAG-KSLCFRPGPALPSTRARQSFPGPRQPNGAQDWRRADSL 401
G P A + A AG K PGP PS PGP+ P G + A
Sbjct: 767 AGPPGA-DGQPGAKGEQGEAGQKGDAGAPGPQGPS-----GAPGPQGPTGVTGPKGARGA 820
Query: 402 PRPQGIT 408
P G T
Sbjct: 821 QGPPGAT 827
Score = 50.4 bits (119), Expect = 3e-06
Identities = 98/347 (28%), Positives = 114/347 (32%), Gaps = 80/347 (23%)
Query: 114 APGAGEAEGLPEGTQAAG-PAPAGKEHRKQDAETPPPPDPPAPETLLAP-PPLPSTPDP- 170
A G +G+P +AG P AG P P PP P+ P P T +P
Sbjct: 337 ASGNPGTDGIPGAKGSAGAPGIAGAPG------FPGPRGPPGPQGATGPLGPKGQTGEPG 390
Query: 171 ---------------PRRELRAPSPPVEH-PRLLRSVPTPLVMAQKISERMA-GNEALSP 213
P AP P E R R P + ER A GN
Sbjct: 391 IAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGF-- 448
Query: 214 TSPFREGRPGEWRTPAARGPR--------SGDPGPGPSHPAQPKAPRF--------PSNI 257
P ++G G P RGP +GDPG P P P A P
Sbjct: 449 --PGQDGLAGPKGAPGERGPSGLAGPKGANGDPGR-PGEPGLPGARGLTGRPGDAGPQGK 505
Query: 258 IVTNGAAREPRRTLSRAAVSVQERRAQV-LATIHGHAGAFPAAGDAGE-GAPGGGSSPER 315
+ +GA E R Q R Q + G GA G AGE G PG
Sbjct: 506 VGPSGAPGEDGRP---GPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPGL--- 559
Query: 316 VARGRGLPGP-AESLRAGGQAPRGPALANGF-----PSAHEALKSAPSSFAPAGKSLCFR 369
RGLPG E+ AG P GPA G PS + L P GK
Sbjct: 560 ----RGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGK----- 610
Query: 370 PG----------PALPSTRARQSFPGPRQPNGAQDWRRADSLPRPQG 406
PG P L R + FPG R GAQ + LP G
Sbjct: 611 PGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPG 657
Score = 42.7 bits (99), Expect = 6e-04
Identities = 87/321 (27%), Positives = 103/321 (32%), Gaps = 69/321 (21%)
Query: 112 QPAPG-AGE-----AEGLPEGTQAAGP-----APAGKEHRKQDAETPPP--PDPPAPETL 158
Q APG AGE A G P G GP AP + QD P P P L
Sbjct: 410 QGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGL 469
Query: 159 LAPPPLPSTPDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGNEALSPTSPFR 218
P P P P + R L P K+ A P
Sbjct: 470 AGPKGANGDPGRPGE------PGLPGARGLTGRPGDAGPQGKVGPSGA---------PGE 514
Query: 219 EGRPGEWRTPAARGPRSGDPG----PGPSHPAQPKAPRFPSNIIVTNGAAREPRRTLSRA 274
+GRPG P +G R G PG PGP GA EP + +
Sbjct: 515 DGRPG---PPGPQGAR-GQPGVMGFPGP------------------KGANGEPGKAGEKG 552
Query: 275 AVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPGGGSSPERVARG----RGLPG----PA 326
A L + G G AAG G P G E+ A G +GLPG P
Sbjct: 553 LPG-----APGLRGLPGKDGETGAAGPPGPAGP-AGERGEQGAPGPSGFQGLPGPPGPPG 606
Query: 327 ESLRAGGQAPRGPALANGFPSAHEALKSAPSSFAPAGKSLCFRPG-PALPSTRARQSFPG 385
E + G Q G A A G +P + L G P P T + G
Sbjct: 607 EGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASG 666
Query: 386 PRQPNGAQDWRRADSLPRPQG 406
P P GAQ +P +G
Sbjct: 667 PAGPPGAQGPPGLQGMPGERG 687
Score = 42.4 bits (98), Expect = 8e-04
Identities = 47/180 (26%), Positives = 62/180 (34%), Gaps = 20/180 (11%)
Query: 216 PFREGRPGEWRTPAARGPRSGDPGPGPSHPAQPKAPRFPSNIIVTNGA--AREPRRTLSR 273
P +G+PG G + PGP P+ P+ P+ + GA A+ P
Sbjct: 770 PGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP-----P 824
Query: 274 AAVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPGGGSSPERVARGRGLPGPAESLRAGG 333
A +V G G+ G G P G P+ G PG A G
Sbjct: 825 GATGFPGAAGRV-----GPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAG--EPGL 877
Query: 334 QAPRGPALANGFP--SAHEALKSAPSSFAPAGKSLCFRPGPALPSTRARQSFPGPRQPNG 391
Q P GP G P + P AG+ R LP R + FPG P+G
Sbjct: 878 QGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQ----RGIVGLPGQRGERGFPGLPGPSG 933
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 67.4 bits (163), Expect = 2e-11
Identities = 85/298 (28%), Positives = 104/298 (34%), Gaps = 55/298 (18%)
Query: 113 PAPGAGEAEGLP-EGTQAAGPAPAGKEHRKQDAETPPPPDPPAPETLLAPPPLPSTPDPP 171
PA AG P EG A P P + P P PP+P P +P+ P PP
Sbjct: 67 PAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRR----PLVPAGPAPP 122
Query: 172 RRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGNEALSPTSPFREGRPGEWRTPAAR 231
+LR PP VP +A AG E +P P + P A
Sbjct: 123 AAKLR--PPPEGSAGSCAPVPAAAAVA-------AGPEP-APAGPAKPAGPAALAARAGP 172
Query: 232 GPRSG---DPGPGPSHPAQPKAPRFPSNIIVTNGAAREPRRTLSRAAVSVQERRAQVLAT 288
GP G PGPGP PA P A + NG+A A
Sbjct: 173 GPGPGPGPGPGPGPGKPAGPGAAQ------TLNGSA----------------------AL 204
Query: 289 IHGHAGAFPAAGDAGEGAPGGGSSPERVARGRGLPGPAESLRAGGQAPRGPALAN-GFPS 347
++ H A PA G P+ A G + P G AP PA +
Sbjct: 205 LNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPP---FVGAAAPPAPAAPSPPAAP 261
Query: 348 AHEALKSAPSSFAPAGKSLCFRPG-PALPSTRARQSFPGPRQPNGAQDWRRADSLPRP 404
A A +AP PA +L PG PA P T A P P AQ+ A + P P
Sbjct: 262 APAAPAAAPPPPPPAPATLARPPGHPAGPPTAA----PAVPPPAAAQNGGSAGAAPAP 315
Score = 51.2 bits (121), Expect = 2e-06
Identities = 65/237 (27%), Positives = 83/237 (35%), Gaps = 38/237 (16%)
Query: 113 PAPGAGEAEGLPEGTQAA--------------GPAPAGKEHRKQDAETPPPPDPPAPETL 158
P PG G G P G AA APA A P P P AP T+
Sbjct: 178 PGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTV 237
Query: 159 LAPPPLPSTPDPPRRELRAPSPP-VEHPRLLRSVPTPLVMAQKISERMAGNEALSPTSPF 217
+ PP PP APSPP P + P P A R G+ A PT+
Sbjct: 238 IQTPPFVGAAAPPAP--AAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAP 295
Query: 218 REGRPGEWR-----------TPAARGPR--SGDPGPG--PSHPAQPKAPRFPSNIIVTNG 262
P + PAA GP SG PGPG + PA P ++
Sbjct: 296 AVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVV---Q 352
Query: 263 AAREPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPGGGSSPERVARG 319
AA +TL+ + + + T+ GA P+ APG + + A G
Sbjct: 353 AAPPAAQTLAASGPASTAASMVIGPTMQ---GALPSPAAVPPPAPGTPTGLPKGAAG 406
Score = 43.5 bits (101), Expect = 4e-04
Identities = 43/134 (32%), Positives = 55/134 (41%), Gaps = 18/134 (13%)
Query: 267 PRRTLSRAAVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPGGGSSPERVARGRGLPGPA 326
PR RAA + V + G AGA PAA EGAPG ++PE GR PG
Sbjct: 45 PRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAA--PAEGAPG--AAPEPPPAGRARPGGG 100
Query: 327 ESLRAGGQAPRGPALANGFPSAHEALKSAPSSFA------PAGKSLCFRPGPAL------ 374
R G +PR P + G L+ P A PA ++ P PA
Sbjct: 101 GPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKP 160
Query: 375 --PSTRARQSFPGP 386
P+ A ++ PGP
Sbjct: 161 AGPAALAARAGPGP 174
Score = 43.5 bits (101), Expect = 4e-04
Identities = 52/185 (28%), Positives = 63/185 (34%), Gaps = 19/185 (10%)
Query: 201 ISERMAGNEALSPTSPFREGRPGEWRTPAARG-PRSGDPGPGPSHPAQPKAPRFPSNIIV 259
+S AG P +P EG PG P G R G GP P P+ P P+
Sbjct: 63 VSGSPAGAAGAGPAAP-AEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAP 121
Query: 260 TNGAAREPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPGGGSS-PERVAR 318
R P + + V A A P AG P G ++ R
Sbjct: 122 PAAKLRPPPEGSAGSCAPVPAAAA---------VAAGPEPAPAGPAKPAGPAALAARAGP 172
Query: 319 GRGLPGPAESLRAGGQAPRGPALA---NG---FPSAHEALKSAPSSFAPAGKSLCFRPGP 372
G G PGP G P GP A NG ++H A A S +L P P
Sbjct: 173 GPG-PGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKP 231
Query: 373 ALPST 377
A P T
Sbjct: 232 AAPGT 236
Score = 43.5 bits (101), Expect = 4e-04
Identities = 89/371 (23%), Positives = 114/371 (30%), Gaps = 70/371 (18%)
Query: 104 PEDVIDLVQPAPGAGEAEGLPEGTQAAGPAPAGKEHRKQDAETPPPPDPPAPETLLAPPP 163
PE P P A PE A PAG A P P P P P
Sbjct: 130 PEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGP-----GPGP 184
Query: 164 LPSTPDPP------------RRELRAPSPPV----EHPRLLRSVPTPLVMAQKI-SERMA 206
P P P A +P V P L +P P I +
Sbjct: 185 GPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFV 244
Query: 207 GNEALSPTSPFREGRPGEWRTPAARGPRSGDPGPGPS---------HPAQP--KAPRFPS 255
G A +P +P P PA P + P P P+ HPA P AP P
Sbjct: 245 G--AAAPPAPAAPSPPA---APAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPP 299
Query: 256 NIIVTNGAAREPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPGGGSSPER 315
NG S A A A + G G P A A SP+R
Sbjct: 300 PAAAQNGG--------SAGAAPAPAPAAGGPAGVSGQPG--PGAAAAAPAPGVKAESPKR 349
Query: 316 VARGRGLPGPAESLRAGGQAPR------GPALANGFPSAHEALKSAPSSFAPAG------ 363
V + P A++L A G A GP + PS AP + P G
Sbjct: 350 VV--QAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGT--PTGLPKGAA 405
Query: 364 ----KSLCFRPGPALPSTRA--RQSFPGPRQPNGAQDWRRADSLPRPQGITVQFAGRGSS 417
+SL P RA + PR P Q+ + P G+ + + G
Sbjct: 406 GAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQL 465
Query: 418 EEARREALRKL 428
++AL ++
Sbjct: 466 LMIPQQALAQM 476
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 63.2 bits (152), Expect = 5e-10
Identities = 89/329 (27%), Positives = 107/329 (32%), Gaps = 52/329 (15%)
Query: 114 APGAGEAEGLPEGTQAAGPA-PAGKEHRKQDAETPPPPDPPAPETLLAPPPLPSTPDPPR 172
APG GLP GP P GK+ K D+E P LP P P
Sbjct: 1419 APGEPGLPGLPGSPGPQGPVGPPGKKGEKGDSED-------------GAPGLPGQPGSPG 1465
Query: 173 RELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGNEALSPTSPFREGRPGEWRTPAARG 232
+ P P+ R P PL A + ER A S P GRPG A+G
Sbjct: 1466 EQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERGPPGPAGSRGLPGVAGRPG------AKG 1519
Query: 233 PRSGDPGPGPSHPAQPKAPRFPSNIIVTNGAAREPRRTLS-------RAAVSVQERRAQV 285
P G PGP + P P + V A P+ R A VQ R
Sbjct: 1520 P-EGPPGP-TGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPP 1577
Query: 286 LATIHGHAGAFPAAGD------AGEGAPGGGSSPERVARGRGLPGPAESL-------RAG 332
+ G G GD G P G S P G PGP + G
Sbjct: 1578 GLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVG 1637
Query: 333 GQAPRGPALANGFP--SAHEALKSAPSSFAPAGKSLCFRPGPALPSTRARQSFPGPRQPN 390
+ GP G P + L+ AP P G+ + P R PG P
Sbjct: 1638 EKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGE----KGDQGDPGEDGRNGSPGSSGPK 1693
Query: 391 GAQDWRRADSLPRPQGITVQFAGRGSSEE 419
G R P P G V G G+ E+
Sbjct: 1694 GD---RGEPGPPGPPGRLVD-TGPGAREK 1718
Score = 54.7 bits (130), Expect = 2e-07
Identities = 95/353 (26%), Positives = 113/353 (32%), Gaps = 93/353 (26%)
Query: 113 PAPGAGEAE----GLPEGTQAAGPAPAGKEHRKQDA-------------ETPPP----PD 151
P P + E G P GPA AG + K D E PP P
Sbjct: 1524 PGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPG 1583
Query: 152 PPAPE-----------TLLAPPPLPSTPDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQK 200
P P+ T A PP S P + + P PP P +
Sbjct: 1584 DPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPP--------GPVGPRGRDGE 1635
Query: 201 ISERMAGNEALSPTSPFREGRPGEWRTPAARGP-----RSGDPG-------PGPSHP--- 245
+ E+ P P + G G P RGP GDPG PG S P
Sbjct: 1636 VGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGD 1695
Query: 246 -AQPKAPRFPSNIIVTNGAAREPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAAGDAG- 303
+P P P ++ T ARE R G G GD G
Sbjct: 1696 RGEPGPPGPPGRLVDTGPGAREKGEPGDR-----------------GQEGPRGPKGDPGL 1738
Query: 304 EGAPGGGSSPERVARG-RGLPGPA--ESLR--AGGQAPRGPALANGFPSAHEALKSAPSS 358
GAPG ER G RG PGP +R AG + RGP +G L P +
Sbjct: 1739 PGAPG-----ERGIEGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDG----RSGLDGKPGA 1789
Query: 359 FAPAGKS----LCFRPG-PALPSTRARQSFPGPRQPNGAQDWRRADSLPRPQG 406
P+G + PG LP R Q PGP P G D P G
Sbjct: 1790 AGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNG 1842
Score = 49.7 bits (117), Expect = 5e-06
Identities = 82/312 (26%), Positives = 105/312 (33%), Gaps = 51/312 (16%)
Query: 114 APGAGEAEGLPEGTQAAGPAPAGKEHRKQDAETPPPPDPPAPETLLAPPPLPSTPDPPRR 173
A G GEA E + G++ R P P PP P P P S +P
Sbjct: 2048 AGGVGEAGRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGP-----PGPKVSVDEPGPG 2102
Query: 174 ELRAPSPP-------------VEHPRLLRSVPTPLVMAQKISERMAGNEALSPTSPFREG 220
PP + P+ R VP + + G + +P P G
Sbjct: 2103 LSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPG--IKGDRGEPGPRGQDG-NPGLPGERG 2159
Query: 221 RPGEWRTPAARGPRS--------GDPG-PGPSHPAQPKAPRFPSNIIVTNGAAREPRRTL 271
G P +GPR GDPG PG A P P+ PS + G P R L
Sbjct: 2160 MAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGL 2219
Query: 272 SRAAVSVQERRAQVLATIHGHAGAFPAAGDAGE----GAPG-GGSSPERVARGR------ 320
+ +V + + G G+ G GE GAPG G+S + RG
Sbjct: 2220 TGPTGAVGLPGPPGPSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGS 2279
Query: 321 -GLPGPAESLRAGGQAPRGPALANGFPSAHEALKSAPSSFAPAGKSLCFRPGPALPSTRA 379
GLPGP G G P A + K AP A L PG +
Sbjct: 2280 PGLPGPVGPKGEPGPTGAPGQAVVGLPGA-KGEKGAPGGLA---GDLVGEPG-----AKG 2330
Query: 380 RQSFPGPRQPNG 391
+ PGPR G
Sbjct: 2331 DRGLPGPRGEKG 2342
Score = 48.5 bits (114), Expect = 1e-05
Identities = 78/277 (28%), Positives = 93/277 (33%), Gaps = 34/277 (12%)
Query: 153 PAPETLLAPPPLPSTPDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGNEALS 212
P PE P +P LR P P L P S G
Sbjct: 1242 PRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPGPQGPPGSATAKGERGFP 1301
Query: 213 -----PTSPFREGRPGEWRTPAARGPRSGDPG-PGPSHPAQPKAPRFPSNIIVTNGAARE 266
P SP R G P TP A G + G PG PGP + PR P G
Sbjct: 1302 GADGRPGSPGRAGNP---GTPGAPGLK-GSPGLPGPRGDPGERGPRGP------KGEPGA 1351
Query: 267 PRRTLSRAAVSVQERRAQVLATIHGHAGAFPAAGDAG----EGAPGGGSSPERVARG-RG 321
P + + + R+ + G G GD G G PG ++ RG RG
Sbjct: 1352 PGQVIGGEGPGLPGRKGDPGPS--GPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERG 1409
Query: 322 LPGPAESLRAGGQAPRGPALANGFPSA--HEALKSAPSSFAPAGKSLCFRPG-PALPSTR 378
PGP E GG AP P L G P + + P G S PG P P +
Sbjct: 1410 PPGPGE----GGIAPGEPGLP-GLPGSPGPQGPVGPPGKKGEKGDSEDGAPGLPGQPGSP 1464
Query: 379 ARQSFPGPRQPNGAQDWRRADSLPRPQGITVQFAGRG 415
Q GPR P GA + P P G + RG
Sbjct: 1465 GEQ---GPRGPPGAIGPKGDRGFPGPLGEAGEKGERG 1498
Score = 45.4 bits (106), Expect = 1e-04
Identities = 37/108 (34%), Positives = 45/108 (41%), Gaps = 10/108 (9%)
Query: 291 GHAGAFPAAGDAG-EGAPGG-GSSPERVARGR----GLPGPAESLRAGGQAPRGPALANG 344
G G GD G +G PG G E+ RG G PGP+ + G P GP + G
Sbjct: 2674 GKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGN--DGSAGPPGPPGSVG 2731
Query: 345 FPSAHEALKSAPSSFAPAGKSLCFRPG-PALPSTRARQSFPGPRQPNG 391
P E L+ P G+ + PG P P R Q PGP P G
Sbjct: 2732 -PRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGPAGPRG 2778
Score = 43.5 bits (101), Expect = 4e-04
Identities = 70/272 (25%), Positives = 83/272 (30%), Gaps = 59/272 (21%)
Query: 152 PPAPETLLAPPPLPSTPDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGNEAL 211
PP P L P P P P R A + ER E
Sbjct: 2026 PPGPSGLAGEPGKPGIPGLPGRAGGVGE------------------AGRPGERGERGEKG 2067
Query: 212 SPTSPFREGRPGEWRTPAARGPRS-----GDPGPGPSHPAQPKAPRFPSNIIVTNGAARE 266
R+G PG TP GP +PGPG S P + GA E
Sbjct: 2068 ERGEQGRDGPPGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLK---------GAKGE 2118
Query: 267 PRRTLSRAAVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPG--GGSSPER---VARGRG 321
P + +R + G G P D G PG G + PE + RG
Sbjct: 2119 PGSNGDQGPKG--DRGVPGIKGDRGEPG--PRGQDGNPGLPGERGMAGPEGKPGLQGPRG 2174
Query: 322 LPGPAESLRAGGQAPRGPALANGF-----PSAHEALKSAPSSFAPAGKSLCFRPGPALPS 376
PGP GG GP A G P LK P P G+ L G
Sbjct: 2175 PPGPV-----GGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGLTGPTGAV--- 2226
Query: 377 TRARQSFPGPRQPNGAQDWRRADSLPRPQGIT 408
PGP P+G + + LP G T
Sbjct: 2227 -----GLPGPPGPSGLVGPQGSPGLPGQVGET 2253
Score = 42.4 bits (98), Expect = 8e-04
Identities = 101/367 (27%), Positives = 120/367 (32%), Gaps = 75/367 (20%)
Query: 109 DLVQPAP-GAGEAEGLPEGTQAAGPAPAGKEHRKQDAETPPP------PDPPAPETLLAP 161
D +P P G GLP AGP GK + P P P PP L P
Sbjct: 2139 DRGEPGPRGQDGNPGLPGERGMAGPE--GKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGP 2196
Query: 162 --PPLPS-------TPDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGN--EA 210
P PS PP R L P+ V P P+ LV Q S + G E
Sbjct: 2197 AGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPG--PPGPSGLVGPQG-SPGLPGQVGET 2253
Query: 211 LSPTSPFREGRPGEWRTPAARGPRSGDPG-PGPSHP-AQPKAPRFPSNIIV-TNGAAREP 267
P +P R+G G+ + G G PG PGP P +P P +V GA E
Sbjct: 2254 GKPGAPGRDGASGKDGDRGSPGV-PGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEK 2312
Query: 268 RRTLSRAAVSVQERRAQVLATIHGHAGAFPAAGDAGE----------GAPG--------- 308
A V E A+ + G G AG AGE GAPG
Sbjct: 2313 GAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPG 2372
Query: 309 -------GGSSPERVARGRGLPG----------PAESLRAGGQAPRGPALANGF--PSAH 349
G P V GLPG P ++ G GP+ G P
Sbjct: 2373 VGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGR 2432
Query: 350 EALKSA------PSSFAPAGKSLCFR----PGPALPSTRARQSFPGPRQPNGAQDWRRAD 399
E + P S P G S PG LP R + PG R +G
Sbjct: 2433 EGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGPR 2492
Query: 400 SLPRPQG 406
L P G
Sbjct: 2493 GLTGPPG 2499
Score = 41.2 bits (95), Expect = 0.002
Identities = 57/227 (25%), Positives = 75/227 (33%), Gaps = 11/227 (4%)
Query: 171 PRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGNEALSPTSPFREGRPGEWRTPAA 230
P+ + P PP RL+ + P + G P G PGE
Sbjct: 1692 PKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRG-PKGDPGLPGAPGERGIEGF 1750
Query: 231 RGPRSGDPGPGPSHPAQPKAPRFPSNIIVTNGAAREPRRT----LSRAAVSVQERRAQVL 286
RGP PG PA K R P + +G +P + AA + L
Sbjct: 1751 RGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGL 1810
Query: 287 ATIHGHAGAFPAAGDAG-EGAPGGGSSPERVARGRGLPG-PAESLRAGGQAPRGPALANG 344
+ G G +G G G PG P + G PG P E R G + G + G
Sbjct: 1811 PGLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGK-NGEPGDPGEDGRKGEKGDSGASGREG 1869
Query: 345 FPSAHEALKSAPSSFAPAGKSLCFRPGPALPSTRARQSFPGPRQPNG 391
+ + AP P G PGP P + PG P G
Sbjct: 1870 -RDGPKGERGAPGILGPQGPP--GLPGPVGPPGQGFPGVPGGTGPKG 1913
Score = 41.2 bits (95), Expect = 0.002
Identities = 93/350 (26%), Positives = 119/350 (34%), Gaps = 64/350 (18%)
Query: 92 PSLEESTSSPSEPEDVIDLVQPAPGAGEAEGLPEGTQAAG-PAPAGKEHRKQDAETP--- 147
P L + P P + + +P PG +G P A G P G + K D P
Sbjct: 2078 PGLPGTPGPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIK 2137
Query: 148 PPPDPPAPETLLAPPPLPSTPDPPRRELRAP--SPPVEHPRLLRSVPTPL----VMAQKI 201
P P P LP R + P P ++ P R P P+
Sbjct: 2138 GDRGEPGPRGQDGNPGLPG-----ERGMAGPEGKPGLQGP---RGPPGPVGGHGDPGPPG 2189
Query: 202 SERMAGNEALSPTSPF-REGRPGEWRTP--AARGPRS--GDPG-PGPSHPAQPK-APRFP 254
+ +AG P P +G PGE P GP G PG PGPS P+ +P P
Sbjct: 2190 APGLAG--PAGPQGPSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPSGLVGPQGSPGLP 2247
Query: 255 SNIIVTNGAAREPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAAGDAG----------- 303
+ T G P R A+ +R + + G G G+ G
Sbjct: 2248 GQVGET-GKPGAPGR--DGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAVVG 2304
Query: 304 -------EGAPGGGSSP---ERVARG-RGLPGP----AESLRAGGQAPRGPALANGFPSA 348
+GAPGG + E A+G RGLPGP E+ RAG G G P
Sbjct: 2305 LPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGP 2364
Query: 349 HEALKSAPSSFAPAGKSLCFRPG-------PALPSTRARQSFPGPRQPNG 391
+ K P P PG P LP FPG P G
Sbjct: 2365 -KGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRG 2413
Score = 40.8 bits (94), Expect = 0.002
Identities = 72/260 (27%), Positives = 89/260 (34%), Gaps = 44/260 (16%)
Query: 117 AGEAEGLPEGTQAAGPAPAGKEHRKQDAE--TPPPPDPPAPETLLAPPPLPSTP------ 168
AGE E Q P P G + +P PP PP + L P LP P
Sbjct: 2347 AGEPGDPGEDGQKGAPGPKGFKGDPGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFP 2406
Query: 169 --DPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGNEAL-SPTSPFREGRPGEW 225
PR E+ P P E R + P G E + P P G PG
Sbjct: 2407 GQTGPRGEMGQPGPSGE-----RGLAGP-----------PGREGIPGPLGP--PGPPGSV 2448
Query: 226 RTPAARGPRSGDPGPGPSHPAQPKAPRFPSNIIVTNG-AAREPRRTLSRAAVSVQERRAQ 284
P A G + PG P P+ R I +G +E R L+ S ER +
Sbjct: 2449 GPPGASGLKGDKGDPGVGLPG-PRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEK 2507
Query: 285 VLATIHGHAGAFPAAGDAGEGAPGGGSSPERVARG-RGLPGPAESLRAGGQAPRGPALAN 343
G G+ GD G+ A G R A+G G GP G +GP N
Sbjct: 2508 ------GDVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGP-----RGLDGDKGPRGDN 2556
Query: 344 GFPSAHEALKSAPSSFAPAG 363
G P + K P AG
Sbjct: 2557 GDP-GDKGSKGEPGDKGSAG 2575
Score = 40.0 bits (92), Expect = 0.004
Identities = 84/341 (24%), Positives = 108/341 (31%), Gaps = 90/341 (26%)
Query: 115 PGAGEAEGLPEGTQAAGPA-PAGKEHRKQDAETPPPPDPPAPETLLAPPPLPSTPDPPRR 173
PG GL AAGP+ P G + D P + L P P P P
Sbjct: 1775 PGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKPGE 1834
Query: 174 ELRA--------PSPPVEHPRLLRSVPTPLVMAQKISERMAGNEALSPTSPFREGRPGEW 225
+ + P P E R +K +G E R+G GE
Sbjct: 1835 DGKPGLNGKNGEPGDPGEDGR----------KGEKGDSGASGREG-------RDGPKGER 1877
Query: 226 RTPAARGPRSGDPG-PGPSHPAQPKAPRFPSN-----------------IIVTNGAAREP 267
P GP+ G PG PGP P P P + G EP
Sbjct: 1878 GAPGILGPQ-GPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEP 1936
Query: 268 R------RTLSRAAVSVQERRAQVLATIHGHAGAFPAA--------GDAGEGAPGGGSSP 313
R L A + R +++ T +G+F GD+GE P G P
Sbjct: 1937 GSVPNVDRLLETAGIKASALR-EIVETWDESSGSFLPVPERRRGPKGDSGEQGPPGKEGP 1995
Query: 314 -----ERVARG-RGLPGP--AESLRAGGQAPRGPALANGFPSAHEALKSAPSSFAPAGKS 365
ER +G RG PGP L G + P GP+ G P + P G++
Sbjct: 1996 IGFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEP-GKPGIPGLPGRAGGVGEA 2054
Query: 366 LCFRPG-------------------PALPSTRARQSFPGPR 387
RPG P LP T PGP+
Sbjct: 2055 --GRPGERGERGEKGERGEQGRDGPPGLPGTPGPPGPPGPK 2093
>gi|7657335 misshapen/NIK-related kinase isoform 1 [Homo sapiens]
Length = 1295
Score = 60.1 bits (144), Expect = 4e-09
Identities = 72/254 (28%), Positives = 104/254 (40%), Gaps = 52/254 (20%)
Query: 150 PDPPAPETLLAPP-PLPSTPDPPRRELRAPSPP----VEHPRLLRSVPTPLVMAQKISER 204
P+PP P+ PP PL TP P +R + P V H L+ P+ +Q + ++
Sbjct: 547 PEPPIPQASPGPPGPLSQTP-PMQRPVEPQEGPHKSLVAHRVPLKPYAAPVPRSQSLQDQ 605
Query: 205 MAGNEALSPTSPFRE-GRPGEWRTPAARG--------PRSGDPGPGPSHP--------AQ 247
N A P S + P TP+ARG P S PGP P+ P A
Sbjct: 606 PTRNLAAFPASHDPDPAIPAPTATPSARGAVIRQNSDPTSEGPGPSPNPPAWVRPDNEAP 665
Query: 248 PKAPRFPSNI---IVTNGA-AREPRRTLSRAAVSVQ------ERRAQVLATIHGHAGAFP 297
PK P+ S+I + T+GA P + + + ++ ER VL HGH P
Sbjct: 666 PKVPQRTSSIATALNTSGAGGSRPAQAVRASNPDLRRSDPGWERSDSVLPASHGH---LP 722
Query: 298 AAGDAGEGAPGGGSSPE-----------RVARGRGLPG-PAESL----RAGGQAPRGPAL 341
AG G S P+ + R PG PA+ + R +APR P
Sbjct: 723 QAGSLERNRVGVSSKPDSSPVLSPGNKAKPDDHRSRPGRPADFVLLKERTLDEAPRPPKK 782
Query: 342 ANGFPSAHEALKSA 355
A + S+ E ++S+
Sbjct: 783 AMDYSSSSEEVESS 796
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 59.7 bits (143), Expect = 5e-09
Identities = 52/168 (30%), Positives = 69/168 (41%), Gaps = 20/168 (11%)
Query: 95 EESTSSPSEPEDVIDLVQPAPGAGEAEGLPEGTQAAGPAPAGKEHRKQDAETPPPPDPPA 154
EE E E+ + P A + E PAP+ + +PPPP P
Sbjct: 372 EEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPP 431
Query: 155 PETLLAPPPLPSTPDPPRRELRAPSPPVEHPRLL-----RSVPTPLVMAQKISERMAGNE 209
P ++PPPLPS P PP +E + SPP P R TP A++ + R AG E
Sbjct: 432 PPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAAR-AGPE 490
Query: 210 ALSPTSPFREGRPGEWRTPAARGPRSGDPGPGPSHPAQPKAPRFPSNI 257
SP +P TP+ +G P P S PK+ F NI
Sbjct: 491 GTSPPTP----------TPST---ATGGP-PEDSPTVAPKSTTFLKNI 524
Score = 47.4 bits (111), Expect = 3e-05
Identities = 76/314 (24%), Positives = 102/314 (32%), Gaps = 44/314 (14%)
Query: 113 PAPGAGEAEGLPEGTQAAG----PAPAGKEHRKQDAETPPPPD----PP---APETLLAP 161
P P G L G PAP + R PPP PP +P+ + P
Sbjct: 1884 PLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPP 1943
Query: 162 PPLPSTPDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGN----EALSPTSPF 217
P T P AP P P + + +S A + +L T PF
Sbjct: 1944 PTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPF 2003
Query: 218 REGRPGEWRTPAARGPRSGDPGPGPSHPAQPKAP--RFPSNIIVTNGAAREPRRTLSRA- 274
+E E A G G PG + P + FP ++ G A R
Sbjct: 2004 QE----EIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIE 2059
Query: 275 ------------AVSVQERRAQVLATIHGHAGAFPAA--GDAGEGAPGGGSSPERVARG- 319
A +VQ+ R Q T G A G AG+ A P +
Sbjct: 2060 QLDGVDDGTDSEAEAVQQPRGQ--GTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFV 2117
Query: 320 -RGLPGPAESLRAGGQAPRGPALANGFPSAHEALKSAPSSFAPAGKSLCFRPGPALPSTR 378
+ L GP + GG PR +L P A+ + S + +PA + F P P R
Sbjct: 2118 LKNLGGPGD----GGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVR 2173
Query: 379 ARQSFPGPRQPNGA 392
P P P A
Sbjct: 2174 VLSLGPAPEPPKPA 2187
Score = 45.1 bits (105), Expect = 1e-04
Identities = 43/155 (27%), Positives = 59/155 (38%), Gaps = 13/155 (8%)
Query: 72 LDEDFEEPVLCDGGVCCLCSPSLEESTSSPSEPEDVIDLVQPAPGAGEAEGLPEGTQAAG 131
+DED +P + V + P + S P EP V + LPE ++
Sbjct: 547 MDEDPPKPPKVE--VSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSIL 604
Query: 132 PAPAGKEHRKQDAETPPPPDPPAPETLLAPPPLPSTPDPPRRELRAP--SPPVEHPRLLR 189
P + E PPPP P P +PPP P+T LRAP +P H ++
Sbjct: 605 REPTFR-WTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYE 663
Query: 190 SVPTPLVMAQKISERMAGNEALSPTSPFREGRPGE 224
SV TP + EA P P + P E
Sbjct: 664 SVLTP--------PPLGAPEAPEPEPPPADDSPAE 690
Score = 37.4 bits (85), Expect = 0.027
Identities = 56/216 (25%), Positives = 73/216 (33%), Gaps = 34/216 (15%)
Query: 137 KEHRKQDAETPPPPDPPAPETLLAP-----PPLPSTPDPPRRELRAPSPPVEHPRLLRSV 191
K R+ E PP P +L P PP+P P P RAP+PP S
Sbjct: 541 KTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPP--------ST 592
Query: 192 PTPLVMAQKISERMAGNEALSPTSPFREGRPGEWRTPAARGPRSGDPGPGPSHPAQPKAP 251
P PL ++ R PT FR W + P P P P P P P
Sbjct: 593 PVPLPEKRRSILR-------EPT--FR------WTSLTRELP---PPPPAPPPPPAPSPP 634
Query: 252 RFPSNIIVTNGAAREPRRTLSRAAVSVQER--RAQVLATIHGHAGAFPAAGDA-GEGAPG 308
P+ R P+ T S A + + E L P A D+ E P
Sbjct: 635 PAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAEPEPR 694
Query: 309 GGSSPERVARGRGLPGPAESLRAGGQAPRGPALANG 344
++ R P ++A PAL+NG
Sbjct: 695 AVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNG 730
Score = 32.0 bits (71), Expect = 1.1
Identities = 72/291 (24%), Positives = 101/291 (34%), Gaps = 74/291 (25%)
Query: 92 PSLEESTSSPSEPE-------DVIDLVQPAPGAG---EAEGLPEGTQAAGPAPAGKEHRK 141
P + SP+EPE + + L + AP +AE P G A P +
Sbjct: 679 PEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLL 738
Query: 142 QDAETPPPPDPPAPETLLAPPPLPSTPDPPRRELRAP-----SPPVEHPRLLRSVPTPL- 195
Q + A +T L P LP PP+ +L+ P PP+E R+ PL
Sbjct: 739 QPLQ--------ALQTQLLPQALP----PPQPQLQPPPSPQQMPPLEKARIAGVGSLPLS 786
Query: 196 ------------------VMAQKISERMAGNEALSPTSPFREGRPGEWRTPAARGP-RSG 236
+ Q+ +++A + LSP E G + + RGP RS
Sbjct: 787 GVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEE-VAGAVKQISDRGPVRSE 845
Query: 237 DPG--------PGPSHPAQ-PKAPRFPSNIIVTNGAARE--PRRTLSRAAVSVQERRAQV 285
D GP P Q P+ + V G AR P +A+ +++R Q
Sbjct: 846 DESVEAKRERPSGPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSALPLRDR--QD 903
Query: 286 LAT-------------IHGHAGAFPAAGDAGEGAPGGGSSPERVARGRGLP 323
LAT G AAG GE P G R LP
Sbjct: 904 LATEDTSSASETESVPSRSRRGKVEAAGPGGESEPTGSGGTLAHTPRRSLP 954
Score = 30.0 bits (66), Expect = 4.3
Identities = 36/123 (29%), Positives = 43/123 (34%), Gaps = 31/123 (25%)
Query: 147 PPPPDPPAPETLLAPPPLPSTP-DPPRRELRA------------PSPPVEHPRLLRSVPT 193
P PP PP P TL+ L S P PPR+ +R PP + PRL
Sbjct: 2251 PAPPPPPPPLTLV----LSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEA 2306
Query: 194 PLVMAQKISERMAGNEALSPTSPFREG-----RPGEWRTPAARGPRSGDPGPGPSHPAQP 248
Q G + +P G RPGE PA G+ PGP P
Sbjct: 2307 SEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGE---PA------GEESPGPLQERSP 2357
Query: 249 KAP 251
P
Sbjct: 2358 LLP 2360
>gi|24850117 misshapen/NIK-related kinase isoform 2 [Homo sapiens]
Length = 1303
Score = 59.3 bits (142), Expect = 7e-09
Identities = 74/262 (28%), Positives = 104/262 (39%), Gaps = 60/262 (22%)
Query: 150 PDPPAPETLLAPP-PLPSTPDPPRRELRAPSPP----VEHPRLLRSVPTPLVMAQKISER 204
P+PP P+ PP PL TP P +R + P V H L+ P+ +Q + ++
Sbjct: 547 PEPPIPQASPGPPGPLSQTP-PMQRPVEPQEGPHKSLVAHRVPLKPYAAPVPRSQSLQDQ 605
Query: 205 MAGNEALSPTSPFRE-GRPGEWRTPAARG--------PRSGDPGPGPSHP--------AQ 247
N A P S + P TP+ARG P S PGP P+ P A
Sbjct: 606 PTRNLAAFPASHDPDPAIPAPTATPSARGAVIRQNSDPTSEGPGPSPNPPAWVRPDNEAP 665
Query: 248 PKAPRFPSNI---IVTNGA-AREPRRTLSRAAVSVQ------ERRAQVLATIHGHAGAFP 297
PK P+ S+I + T+GA P + + + ++ ER VL HGH P
Sbjct: 666 PKVPQRTSSIATALNTSGAGGSRPAQAVRASNPDLRRSDPGWERSDSVLPASHGH---LP 722
Query: 298 AAGDAGEGAPGGGSSPE-----------RVARGRGLPG-PAESLRAGG------------ 333
AG G S P+ + R PG PA RA G
Sbjct: 723 QAGSLERNRVGVSSKPDSSPVLSPGNKAKPDDHRSRPGRPASYKRAIGEDFVLLKERTLD 782
Query: 334 QAPRGPALANGFPSAHEALKSA 355
+APR P A + S+ E ++S+
Sbjct: 783 EAPRPPKKAMDYSSSSEEVESS 804
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 58.5 bits (140), Expect = 1e-08
Identities = 91/355 (25%), Positives = 122/355 (34%), Gaps = 70/355 (19%)
Query: 92 PSLEESTSSPSEPEDVIDLVQPAPGAGEAEG------LPEGTQAAGPAP------AGKEH 139
P +S +SP+ P I P G G + P G P+P +
Sbjct: 747 PQAPDSQASPA-PAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPS 805
Query: 140 RKQDAETPPP-------PDPPAPETL-----------LAPP---PLPSTPDPPRRELRAP 178
R Q PP P P AP TL + PP P P+ P PP+ LR
Sbjct: 806 RPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQ 865
Query: 179 SPPVEHPRLLRSVPTPLVMAQKISERMAGNEALSPTSPFREGRPGEWRTPAARGPRSGDP 238
S P E P P P + S +A + S P + + P ++GP
Sbjct: 866 SQPPEGP----LPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPHKSPT 921
Query: 239 GPGPSH----PAQPKAPRFPSNIIVTN--GAAREPRRTLSRAAVSVQERRAQVLATI--H 290
P H PA P P + +VT A +P+ L ER QV + I
Sbjct: 922 PPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALL--------ERFHQVPSGIILQ 973
Query: 291 GHAGAFPAAGDAGEGAPGGGSSPERVARGRGLPGPAESLRAGGQAPRG-PALANGFPSAH 349
AG PAA P+ L PA S+ GQAP G P + P+
Sbjct: 974 NKAGGAPAA-------------PQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPA 1020
Query: 350 EALKSAPSSFAPAGKSLCFRPGPALPSTRARQSFPGPRQPNGAQDWRRADSLPRP 404
+ PA P L +A S GP +P+G Q + L +P
Sbjct: 1021 PMAATGLPPLLPAENKAFASNLPTLNVAKAASS--GPGKPSGLQYESKLSGLKKP 1073
Score = 41.2 bits (95), Expect = 0.002
Identities = 79/335 (23%), Positives = 116/335 (34%), Gaps = 64/335 (19%)
Query: 104 PEDVIDLVQPAPGAGEA------EGLPEGTQAAG-PAPAG-KEHRKQDAETPPPPDPPAP 155
P+ ++ PA GEA + P+ A P P G ++ + Q P P AP
Sbjct: 599 PDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAP 658
Query: 156 ETLLAPPPLPSTPDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGNEA----- 210
P P P P + + P +L + + Q+ S++ E
Sbjct: 659 PQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSV 718
Query: 211 -----LSPTSPFREGRPGEWRTPAAR----GPRSGD-----------------PGPGP-S 243
+S P ++ P TP A+ GP++ D GPGP S
Sbjct: 719 PASVIVSAPPPAQDPAPA---TPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSS 775
Query: 244 HPAQP-KAPRFPSNIIVTNGAAREPRRTLSR-AAVSVQERRAQVLATIHGHA-----GAF 296
P+ P +AP S + + R P R SR +VS + A G F
Sbjct: 776 SPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIF 835
Query: 297 PAAGDAGEGAPGGGSSPERVARGRGLPGPAE-SLRAGGQAPRGPALANGFPSAHEALKSA 355
G P +P PGP + LR Q P GP P+ H S
Sbjct: 836 VIQNQLGVPPPASNPAPT-------APGPPQPPLRPQSQPPEGPLP----PAPHLPPSST 884
Query: 356 PSSFAPAGKSLCFRPGPALPSTRARQSFPGPRQPN 390
S+ A + ++ P P PS Q FP + P+
Sbjct: 885 SSAVASSSETSSRLPAPT-PSDFQLQ-FPPSQGPH 917
Score = 39.3 bits (90), Expect = 0.007
Identities = 33/102 (32%), Positives = 39/102 (38%), Gaps = 22/102 (21%)
Query: 149 PPDPPAPETLLAPPPLPSTPDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGN 208
PP PPA + PPP P P PP ++ V+HP PL G
Sbjct: 1333 PPPPPATLKVAEPPPRPPPPPPPTGQMNG---TVDHPPPAAPERKPL-----------GT 1378
Query: 209 EALSPTSPFRE------GRPGEWR-TPAARGPRSGDPGPGPS 243
P P R+ G PG TPA R R G P P P+
Sbjct: 1379 APHCPRLPLRKTYRENVGGPGAPEGTPAGRA-RGGSPAPLPA 1419
Score = 32.7 bits (73), Expect = 0.66
Identities = 84/410 (20%), Positives = 129/410 (31%), Gaps = 105/410 (25%)
Query: 92 PSLEESTSSPSEPEDVIDLVQPAPGAGEAEGLPEGTQAAGPAPAGKEHRKQDAETPPPP- 150
P L + T P P +Q PGA + P+ Q AGK + P P
Sbjct: 361 PKLYQLTPKPFAPAGATLTIQGEPGALPQQ--PKAPQNLTFMAAGKAGQNVVLSGFPAPA 418
Query: 151 -------DPPAPETLLAPPPLPSTPDPP-----------------------RRELRAPSP 180
PPA T APP P P + L +P
Sbjct: 419 LQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAP 478
Query: 181 PVEHPRLLRSVPT---------------------PLVMAQKISERMAGNEALSPTS---- 215
V+ P+ L ++P P++ Q ++ ++ L+P S
Sbjct: 479 AVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHS 538
Query: 216 -------PFREGRPGEWRTPA--ARGPRSGDPGPGPSHPA-------------------- 246
P + G+P ++ P A G P P+ PA
Sbjct: 539 AHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNT 598
Query: 247 -----QPKAPRFPSN----IIVTNGAAREPRRTLSRAAVSVQERRAQVLATIHGHAGAFP 297
QP P + ++ A + P + + +Q+ +AQ A P
Sbjct: 599 PDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAP 658
Query: 298 AAGDAGEGAPGGGSSPERVARGRGLPG-PAESLRAGGQAPRGPALANGFP-SAHEALKSA 355
+ +PG SSPE++ G+ P L P + P SA S
Sbjct: 659 PQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSV 718
Query: 356 PSSFAPAGKSLCFRPGPALPSTRARQSFPGPRQPNGAQDWRRADSLPRPQ 405
P+S + P PA P A+ + GP+ P+ +A P PQ
Sbjct: 719 PASVIVSAPPPAQDPAPATPV--AKGAGLGPQAPDS-----QASPAPAPQ 761
>gi|19913398 smoothelin isoform a [Homo sapiens]
Length = 940
Score = 58.2 bits (139), Expect = 1e-08
Identities = 67/289 (23%), Positives = 102/289 (35%), Gaps = 46/289 (15%)
Query: 124 PEGTQAAGPAPAGKEHRKQDAETPPPPDPPAPETLLAPPPLPSTPDPPRRELRAPSPP-V 182
P G+ ++ PA E PP +P + L A +P +P+PP PSPP
Sbjct: 194 PPGSTSSSPASPSSSPTPASPE--PPLEPAEAQCLTA--EVPGSPEPP------PSPPKT 243
Query: 183 EHPRLLRSVPTPLVMAQKISERMAGNEALSPTSPFREGRPGEWRTPAARGPRSGDPGPGP 242
P S P Q +++ ++G + TPAA+ P G
Sbjct: 244 TSPEPQESPTLPSTEGQVVNKLLSGPK----------------ETPAAQSPHRGPSDTKR 287
Query: 243 SHPAQPKAPRFPSNIIVTNGAAREPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAAGDA 302
+ A P+ + +++ A+ T + S +R V +H P A
Sbjct: 288 ADVAGPRPCQRSLSVLSPRQPAQNRESTPLASGPSSFQRAGSVRDRVHKFTSDSPMAARL 347
Query: 303 GEGAPGGGSSPERVAR--GRGLPGPAESLRAGGQAPRGPALAN--------GFPSAHEAL 352
+G P SP AR G L + + G + RGP+ + G L
Sbjct: 348 QDGTPQAALSPLTPARLLGPSLTSTTPASSSSGSSSRGPSDTSSRFSKEQRGVAQPLAQL 407
Query: 353 KSAPSSFAPAGKSLCFRP------GPALPSTRARQSFP---GPRQPNGA 392
+S P P G+ L RP GP S P G +P G+
Sbjct: 408 RSCPQEEGPRGRGLAARPLENRAGGPVARSEEPGAPLPVAVGTAEPGGS 456
>gi|19913396 smoothelin isoform b [Homo sapiens]
Length = 915
Score = 57.8 bits (138), Expect = 2e-08
Identities = 67/289 (23%), Positives = 102/289 (35%), Gaps = 46/289 (15%)
Query: 124 PEGTQAAGPAPAGKEHRKQDAETPPPPDPPAPETLLAPPPLPSTPDPPRRELRAPSPP-V 182
P G+ ++ PA E PP +P + L A +P +P+PP PSPP
Sbjct: 194 PPGSTSSSPASPSSSPTPASPE--PPLEPAEAQCLTA--EVPGSPEPP------PSPPKT 243
Query: 183 EHPRLLRSVPTPLVMAQKISERMAGNEALSPTSPFREGRPGEWRTPAARGPRSGDPGPGP 242
P S P Q +++ ++G + TPAA+ P G
Sbjct: 244 TSPEPQESPTLPSTEGQVVNKLLSGPK----------------ETPAAQSPTRGPSDTKR 287
Query: 243 SHPAQPKAPRFPSNIIVTNGAAREPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAAGDA 302
+ A P+ + +++ A+ T + S +R V +H P A
Sbjct: 288 ADVAGPRPCQRSLSVLSPRQPAQNRESTPLASGPSSFQRAGSVRDRVHKFTSDSPMAARL 347
Query: 303 GEGAPGGGSSPERVAR--GRGLPGPAESLRAGGQAPRGPALAN--------GFPSAHEAL 352
+G P SP AR G L + + G + RGP+ + G L
Sbjct: 348 QDGTPQAALSPLTPARLLGPSLTSTTPASSSSGSSSRGPSDTSSRFSKEQRGVAQPLAQL 407
Query: 353 KSAPSSFAPAGKSLCFRP------GPALPSTRARQSFP---GPRQPNGA 392
+S P P G+ L RP GP S P G +P G+
Sbjct: 408 RSCPQEEGPRGRGLAARPLENRAGGPVARSEEPGAPLPVAVGTAEPGGS 456
>gi|19913394 smoothelin isoform c [Homo sapiens]
Length = 917
Score = 57.8 bits (138), Expect = 2e-08
Identities = 67/289 (23%), Positives = 102/289 (35%), Gaps = 46/289 (15%)
Query: 124 PEGTQAAGPAPAGKEHRKQDAETPPPPDPPAPETLLAPPPLPSTPDPPRRELRAPSPP-V 182
P G+ ++ PA E PP +P + L A +P +P+PP PSPP
Sbjct: 194 PPGSTSSSPASPSSSPTPASPE--PPLEPAEAQCLTA--EVPGSPEPP------PSPPKT 243
Query: 183 EHPRLLRSVPTPLVMAQKISERMAGNEALSPTSPFREGRPGEWRTPAARGPRSGDPGPGP 242
P S P Q +++ ++G + TPAA+ P G
Sbjct: 244 TSPEPQESPTLPSTEGQVVNKLLSGPK----------------ETPAAQSPTRGPSDTKR 287
Query: 243 SHPAQPKAPRFPSNIIVTNGAAREPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAAGDA 302
+ A P+ + +++ A+ T + S +R V +H P A
Sbjct: 288 ADVAGPRPCQRSLSVLSPRQPAQNRESTPLASGPSSFQRAGSVRDRVHKFTSDSPMAARL 347
Query: 303 GEGAPGGGSSPERVAR--GRGLPGPAESLRAGGQAPRGPALAN--------GFPSAHEAL 352
+G P SP AR G L + + G + RGP+ + G L
Sbjct: 348 QDGTPQAALSPLTPARLLGPSLTSTTPASSSSGSSSRGPSDTSSRFSKEQRGVAQPLAQL 407
Query: 353 KSAPSSFAPAGKSLCFRP------GPALPSTRARQSFP---GPRQPNGA 392
+S P P G+ L RP GP S P G +P G+
Sbjct: 408 RSCPQEEGPRGRGLAARPLENRAGGPVARSEEPGAPLPVAVGTAEPGGS 456
>gi|237757308 synaptojanin 1 isoform b [Homo sapiens]
Length = 1350
Score = 57.0 bits (136), Expect = 3e-08
Identities = 73/278 (26%), Positives = 101/278 (36%), Gaps = 24/278 (8%)
Query: 91 SPSLEESTSSPSEPEDVIDLVQPAPGAGEAEGLPEGTQAAGPAPAGKEHRKQDAETPPPP 150
SP++ E PS P PG A+ P Q A P P + + + PPPP
Sbjct: 1092 SPTISEGPV-PSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPP 1150
Query: 151 DPPAPETLLAPPPLPSTPDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGNEA 210
P AP T APP P PP R+P+P + + + P+P V A E
Sbjct: 1151 RPVAPPTRPAPPQRP----PPPSGARSPAPTRKEFGGIGAPPSPGV---------ARREM 1197
Query: 211 LSPTSPFREGRPGEWRTPAARGPRSGDPGPGPS--HPAQPKAPRFPSNIIVTNGAAREPR 268
+P SP + R+ + P++G GPGP+ A+P P I AR
Sbjct: 1198 EAPKSPGTTRKDNIGRSQPS--PQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASA 1255
Query: 269 RTL---SRAAVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPGGGSSPERVARGRGLPGP 325
L S++ S + + L AFP A VA GP
Sbjct: 1256 GRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGP 1315
Query: 326 AESLRAGGQAPRGPALANGFPSAHEALKSAPSSFAPAG 363
+L Q P ++ PS S P P+G
Sbjct: 1316 QPNLETPPQPPPRSRSSHSLPS---EASSQPQQEQPSG 1350
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 57.0 bits (136), Expect = 3e-08
Identities = 72/307 (23%), Positives = 109/307 (35%), Gaps = 62/307 (20%)
Query: 113 PAPGAGEAEGLPEGTQAAGPAPAGKEHRKQDAETPPP-----PDPPAPETLLAPPPL--- 164
P+P + E P G + P+P R+ + PPP P PP +PPP
Sbjct: 531 PSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRS 590
Query: 165 PS------------TPDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGNEALS 212
PS +P PP + A PP P R+ P+P +++S + S
Sbjct: 591 PSPRRYSPPIQRRYSPSPPPKRRTASPPP---PPKRRASPSP-PPKRRVSHSPPPKQRSS 646
Query: 213 PTSPFR------EGRPGEWRTPAARGPRSGDPGPGPSHPAQPKAPRFPSN-IIVTNGAAR 265
P + R + R G + + R RS P S +P+AP+ S+ V GA+
Sbjct: 647 PVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASS 706
Query: 266 EPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPGGGSSPERVARGRGLPGP 325
P+R S + + RR P + A S RV+ R + G
Sbjct: 707 SPQRRQSPSPSTRPIRR----------VSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGS 756
Query: 326 AESLRAGGQAPRGPALANGFPSAHEALKSAPSSFAPAGKSLCFRPGPALPSTRARQSFPG 385
E AP P + PS + + PA+P +A+ P
Sbjct: 757 PEPAAKKPPAPPSPVQSQS-PSTNWS--------------------PAVPVKKAKSPTPS 795
Query: 386 PRQPNGA 392
P P +
Sbjct: 796 PSPPRNS 802
Score = 43.9 bits (102), Expect = 3e-04
Identities = 70/294 (23%), Positives = 97/294 (32%), Gaps = 38/294 (12%)
Query: 135 AGKEHRKQDAETPPPPDPPAPETLLAPPP----LPSTPDPPRRELRAPSPPVEHPRLLRS 190
+G + + PP P P+ +PP L + PPRR R PSPP P R
Sbjct: 356 SGSSSSSSSSRSRSPPKKP-PKRTSSPPRKTRRLSPSASPPRRRHR-PSPPATPPPKTRH 413
Query: 191 VPTPLVMAQKISERMAGNEALSPTSPFREGRPGEWRTPAARGPRSGDPGPGPSHPAQPKA 250
PTP Q+ + ++SP GR T + P P P
Sbjct: 414 SPTP----QQSNRTRKSRVSVSP------GRTSGKVTKHKGTEKRESPSPAPK------- 456
Query: 251 PRFPSNIIVTNGAAREPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPGGG 310
P + ++ + E + AA SVQ+RR ++ D+G +
Sbjct: 457 ---PRKVELSE--SEEDKGGKMAAADSVQQRRQYRRQNQQ-------SSSDSGSSSSSED 504
Query: 311 SSPERVARGRGLPGPAESLRAGGQAPRGPALANGFPSAHEALKSAPSSFAPAGKSLCFRP 370
P+R G G A P S + +PS P P
Sbjct: 505 ERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPS---PPPTRRRRSP 561
Query: 371 GPALPSTRARQSFPGPRQPNGAQDWRRADSLPRPQGITVQFAGRGSSEEARREA 424
PA P R R P PR+ + RR PR +Q S RR A
Sbjct: 562 SPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTA 615
Score = 29.3 bits (64), Expect = 7.3
Identities = 72/332 (21%), Positives = 105/332 (31%), Gaps = 48/332 (14%)
Query: 91 SPSLEESTSSPSEPEDVIDLVQPAPGAGEAEGLPEGTQAAGPA--PAGKEHRKQDAETPP 148
S SL S+SS S +P P T+ P+ P + HR TPP
Sbjct: 352 SASLSGSSSSSSSSRSRSPPKKPPKRTSSP---PRKTRRLSPSASPPRRRHRPSPPATPP 408
Query: 149 PPDPPAPETLLAPPPLPSTPDPPRRELRAPSPPVEHPRLL-------RSVPTPLVMAQKI 201
P + P P + R+ + SP ++ R P+P +K+
Sbjct: 409 PKTRHS--------PTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKV 460
Query: 202 ----SERMAGNEALSPTSPFREGRPGEWRTPAARGPRSGDPGPGPSHPAQPKAPRFPSNI 257
SE G + + S + R R + G S ++ + P+
Sbjct: 461 ELSESEEDKGGKMAAADSV-------QQRRQYRRQNQQSSSDSGSSSSSEDERPK---RS 510
Query: 258 IVTNGAAREPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPGGGSSPERVA 317
V NG RR + S R+ Q + G P+ SP
Sbjct: 511 HVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRR---SPSPAPPP 567
Query: 318 RGRGLPGPAESLRAGGQAP--RGPALANGFPSAHEALKSAP------SSFAPAGKSLCFR 369
R R P P R P R P+ P +P +S P K R
Sbjct: 568 RRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKR---R 624
Query: 370 PGPALPSTRARQSFPGPRQPNGAQDWRRADSL 401
P+ P R P P+Q + RR+ SL
Sbjct: 625 ASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSL 656
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 56.6 bits (135), Expect = 4e-08
Identities = 64/240 (26%), Positives = 87/240 (36%), Gaps = 29/240 (12%)
Query: 100 SPSEPEDV-IDLVQPAPGAGEAEGLP---EGTQAAGPAPAGKEHRKQDAETPPPPDP--- 152
+P EP+ + + P A A +P E T A P +E A PPP +P
Sbjct: 983 APEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSP 1042
Query: 153 ----PAPETLLAPPPLPSTPDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGN 208
P PE +P TP+ P A P E +VPTP + S A
Sbjct: 1043 AAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP---EEPTSPAAAVP 1099
Query: 209 EALSPTSPFRE-GRPGEWRTPAARGPRSGDPGPGPSHPAQPKAPRFPSNIIVTNGAAREP 267
PTSP P E +PAA P +P + P+ P FP+ + T P
Sbjct: 1100 TPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPT------P 1153
Query: 268 RRTLSRA-AVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPGGGSSPERVARGRGLPGPA 326
+ S A AV E A A A P ++ A + E + +P PA
Sbjct: 1154 EESASAAVAVPTPEESA-------SPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPA 1206
Score = 53.1 bits (126), Expect = 5e-07
Identities = 79/316 (25%), Positives = 106/316 (33%), Gaps = 33/316 (10%)
Query: 119 EAEGLPEGTQAAGP---APAGKEHRKQDAETPPPPDPPA-----PETLLAPPPLPSTPDP 170
E +G PEG AP + TP P PA PE +P TP+
Sbjct: 966 EEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEE 1025
Query: 171 PRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGNEALSPTSPFRE-GRPGEWRTPA 229
P A PP E +VPTP + S A PTSP P E +PA
Sbjct: 1026 PTSPAAAVPPPEEPTSPAAAVPTP---EEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPA 1082
Query: 230 ARGPRSGDPGPGPSHPAQPKAPRFPSNIIVTNGAAREPRRTLSRAAVSVQERRAQVLATI 289
A P +P + P+ P P+ + T P AAV E A
Sbjct: 1083 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASP-----AAAVPTPEEPA------ 1131
Query: 290 HGHAGAFPAAGDAGEGAPGGGSSPERVARGRGLPGPAESLRAGGQAPRGPALANGFPSAH 349
A A P + AP + E + +P P ES P PA + F +
Sbjct: 1132 -SPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPT-PAESASFAAVV 1189
Query: 350 EALKSAPSSFAPAGKSLCFRPGP-ALPSTRARQSFPGPRQPNGAQDWRRADSLPRPQGIT 408
L+ S A P P A+ +T + P P + A ++ P+ T
Sbjct: 1190 ATLEEPTSPAASV-------PTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPT 1242
Query: 409 VQFAGRGSSEEARREA 424
A + EE A
Sbjct: 1243 SPAAAVPTLEEPTSSA 1258
Score = 31.2 bits (69), Expect = 1.9
Identities = 29/106 (27%), Positives = 40/106 (37%), Gaps = 9/106 (8%)
Query: 93 SLEESTSSPSEPEDVIDLVQPAPGAGEAEGLPEGTQAAGPAPAGKEHRKQDAETPPPPDP 152
+LEE TS + V +PA A E T A P +E A P +
Sbjct: 1211 TLEEFTSPAAS---VPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEEL 1267
Query: 153 PAPETLLAPPPLPSTPDPPRRELRAPSPPVEHPRLLRSVPTPLVMA 198
+P + P P++P L P+ P +VPTP V A
Sbjct: 1268 SSPAASVPTPEEPASPAAAVSNLEEPASPAA------AVPTPEVAA 1307
Score = 30.8 bits (68), Expect = 2.5
Identities = 27/93 (29%), Positives = 39/93 (41%), Gaps = 12/93 (12%)
Query: 92 PSLEESTSSPSEPEDVIDLVQPAPGAGEAEGLPEGTQAAGPAPAGKEHRKQDAETPPPPD 151
P+LEE TSS + ++ P + A +P + A PA A + E P P
Sbjct: 1249 PTLEEPTSSAAA------VLTPEELSSPAASVPTPEEPASPAAA-----VSNLEEPASPA 1297
Query: 152 PPAPETLLAPPPLPSTPDPPRRELRAPS-PPVE 183
P +A P S P P + A + PP+E
Sbjct: 1298 AAVPTPEVAAIPAASVPTPEVPAIPAAAVPPME 1330
>gi|145275189 specifically androgen-regulated protein isoform 1
[Homo sapiens]
Length = 601
Score = 56.2 bits (134), Expect = 6e-08
Identities = 60/248 (24%), Positives = 93/248 (37%), Gaps = 39/248 (15%)
Query: 27 SRGGSLESRSSSSRSRSFTLDDESLKYLTHEEKDVLLFFEETIDSLDEDFEEPVLCDGGV 86
+R GS +S SS+ +RS + D S +L+ EEK+ LLF EETI SLD + + + D
Sbjct: 17 TRVGSCDSMMSSTSTRSGS-SDSSYDFLSTEEKECLLFLEETIGSLDTEADSGLSTD--- 72
Query: 87 CCLCSPSLEESTSSPSEPEDVIDLVQPAPGAGEAEGL----------PEGTQAAGPAPAG 136
E ++ + + QP P G E + E + + P P G
Sbjct: 73 --------ESEPATTPRGFRALPITQPTPRGGPEETITQQGRTPRTVTESSSSHPPEPQG 124
Query: 137 -----------------KEHRKQDAETPPPPDPPAPETLLAPPPLPSTPDPPRRELRAPS 179
+ + + T P LAP P + +AP+
Sbjct: 125 LGLRSGSYSLPRNIHIARSQNFRKSTTQASSHNPGEPGRLAPEPEKEQVSQSSQPRQAPA 184
Query: 180 PPVEHPRLLRSVPTPLVMAQKISERMAGNEALSPTSPFREGRPGEWRTPAARGPRSGDPG 239
P E L V P A + ++ EA P P ++G + TP++ R P
Sbjct: 185 SPQEAALDLDVVLIPPPEAFRDTQPEQCREASLPEGPGQQGHTPQLHTPSSSQEREQTPS 244
Query: 240 PGPSHPAQ 247
S A+
Sbjct: 245 EAMSQKAK 252
Score = 43.1 bits (100), Expect = 5e-04
Identities = 69/286 (24%), Positives = 103/286 (36%), Gaps = 42/286 (14%)
Query: 149 PPDPPAPETLLAPPPLPSTPDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGN 208
P D P L+ P P R + +P+P + P AQ + A
Sbjct: 357 PQDQDEPGLHLSKPTSSIRPKETRAQHLSPAP---------GLAQPAAPAQASAAIPAAG 407
Query: 209 EALSPTSPFREGRPGEWRTPAARGPRSGDPGPGPSHPAQ-PKAPRFPSNIIVTNGAAREP 267
+AL+ +P P + P + P G+ S P PKAPR N A P
Sbjct: 408 KALAQ-APAPAPGPAQGPLPM-KSPAPGNVAASKSMPISIPKAPR-------ANSALTPP 458
Query: 268 RRTLSRAAVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPGGGSSPERVARGRGLPGPAE 327
+ + +++QE L ++ + +G G S P +
Sbjct: 459 K---PESGLTLQESNTPGLRQMNFKSNTLERSGV--------GLSSYLSTEKDASPKTST 507
Query: 328 SLRAGGQAPRGPALANGFPSAHEALKSAPSSFAPAGKSLCFRPGPALPSTRARQSFPGPR 387
SL +G L PS + P+S GK L QS
Sbjct: 508 SLG------KGSFLDKISPSVLRNSRPRPASLG-TGKDFAGIQVGKLADLEQEQS----- 555
Query: 388 QPNGAQDWRRADSLPRPQGITVQFAGRGSSEEARREALRKLGLLRE 433
+ + D LPRP ++V+ + +G E RREAL+KLGLL+E
Sbjct: 556 SKRLSYQGQSRDKLPRPPCVSVKISPKGVPNEHRREALKKLGLLKE 601
Score = 33.5 bits (75), Expect = 0.39
Identities = 34/108 (31%), Positives = 41/108 (37%), Gaps = 9/108 (8%)
Query: 94 LEESTSSPSEPEDVIDLVQPAPGAGEAEGLPEGTQAAGPAPAGKEHRKQDAETPPPPD-- 151
L + TSS E + PAPG + P AA PA AGK + A P P
Sbjct: 367 LSKPTSSIRPKETRAQHLSPAPGLAQPAA-PAQASAAIPA-AGKALAQAPAPAPGPAQGP 424
Query: 152 ----PPAPETLLAPPPLP-STPDPPRRELRAPSPPVEHPRLLRSVPTP 194
PAP + A +P S P PR P E L+ TP
Sbjct: 425 LPMKSPAPGNVAASKSMPISIPKAPRANSALTPPKPESGLTLQESNTP 472
>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
Length = 1626
Score = 55.8 bits (133), Expect = 7e-08
Identities = 80/303 (26%), Positives = 100/303 (33%), Gaps = 62/303 (20%)
Query: 115 PGA-GEAEGLPEGTQAAGPAPAGKEHRKQDAETPPPPDPPAPETLLAPPPLPSTPDPPRR 173
PG GE E + P G K +A PP P +L P P P+
Sbjct: 812 PGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKG 871
Query: 174 ELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGNEALSPTS-PFREGRPGEWRTPAARG 232
E P P E + R PT P +G+ G P A
Sbjct: 872 EKGDPGLPGE---------------PGLQGRPGELGPQGPTGPPGAKGQEGAHGAPGA-- 914
Query: 233 PRSGDPGPGPSHPAQPKAPRFPSNIIVTNGAAREPRRTLSRAAVSVQERRAQVLATIHGH 292
+G+PG P H P P P + G P + ER + A G
Sbjct: 915 --AGNPG-APGHVGAP-GPSGPPGSVGAPGLRGTPGKD--------GERGEKGAAGEEGS 962
Query: 293 AGAFPAAGDAG----EGAPGGGSSPERVARGR-GLPGP------------AESLRAGGQA 335
G GD G G PG G E RG GLPGP +E+ GGQ
Sbjct: 963 PGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQC 1022
Query: 336 PRGPALANGFPSAHEALKSAPSSFAPAGKSLCFRPGPA-------LPSTRARQSFPGPRQ 388
+G A G P +P S G + PGP+ P +R FPGP+
Sbjct: 1023 VKGDRGAPGIP-------GSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPGPQG 1075
Query: 389 PNG 391
P G
Sbjct: 1076 PAG 1078
Score = 42.4 bits (98), Expect = 8e-04
Identities = 80/332 (24%), Positives = 103/332 (31%), Gaps = 52/332 (15%)
Query: 104 PEDVIDLVQPAPGAGEAEGLPEGTQAAGPAPAGKEHRKQDAETPPPPDPPAPETLLAPPP 163
P+ I + P GA +G +G GP G++ K P PP + + P
Sbjct: 497 PKGDIGAIGPV-GAPGPKG-EKGDVGIGPFGQGEKGEKGSLGLPGPPGRDGSKGMRGEPG 554
Query: 164 LPSTPDPPRRE-LRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGNEALSPTSPFREGRP 222
P P +R P P P V P + ++ + G + F G+P
Sbjct: 555 ELGEPGLPGEVGMRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGF-PGKP 613
Query: 223 GEWRTPAARGPRSGDPGP----GPSHPAQPKAPRFPSNIIVTNGAAREPRRTLSRAAVSV 278
G+ GP SG GP G PA P P P +++ G E R
Sbjct: 614 GDTGQQGRPGP-SGVAGPQGEKGDVGPAGP--PGVPGSVVQQEGLKGEQGAPGPR----- 665
Query: 279 QERRAQVLATIHGHAGAFPAAGDAGEGAPGGGSSPERVARGRGLPG----PAESLRAGGQ 334
GH GA G G P G P + RG G P G Q
Sbjct: 666 ------------GHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQ 713
Query: 335 APRGPALANGFPSAHEALKSAPSSFAPAGKSLCFRPGPALPSTRARQSFPGPRQPNGAQD 394
P GP G P P G P LP PGP P G
Sbjct: 714 GPPGPPGVPGPPG-------------PGGS-------PGLPGEIGFPGKPGPPGPTGPPG 753
Query: 395 WRRADSLPRPQGITVQFAGRGSSEEARREALR 426
+ P P G + RG + LR
Sbjct: 754 KDGPNGPPGPPGTKGEPGERGEDGLPGKPGLR 785
Score = 42.0 bits (97), Expect = 0.001
Identities = 79/315 (25%), Positives = 93/315 (29%), Gaps = 77/315 (24%)
Query: 112 QPAPGAGEAEGLPEGTQAAGP-------APAGKEHRKQDAETPPPPDPPAPETLLAPPPL 164
Q APG +G P A GP P G + + PP P L PP
Sbjct: 659 QGAPGPRGHQGAPGPPGARGPIGPEGRDGPPGLQGLRGKKGDMGPPGIPGLLGLQGPPGP 718
Query: 165 PSTPDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGNEALSPTSPFREGRPGE 224
P P PP SP P G PG+
Sbjct: 719 PGVPGPP------------------------------------GPGGSPGLPGEIGFPGK 742
Query: 225 WRTPAARGPRSGDPGPGPSHPAQPKAPRFPSNIIVTNGAAREPRRTLSRAAVSVQERRAQ 284
P GP D GP P P P G P + R + Q
Sbjct: 743 PGPPGPTGPPGKDGPNGP--PGPPGTKGEPGE----RGEDGLPGKPGLRGEIGEQ----- 791
Query: 285 VLATIHGHAGAFPAAGDAG-EGAPG----GGSSPERVARGR-GLPGPAESLRAGGQA-PR 337
G AG G+AG GAPG G ++ +G GLPG G+A P
Sbjct: 792 ------GLAGRPGEKGEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPA 845
Query: 338 GPALANGFPSAHEALKSAPSSFAPAGKSLCFRPGPALPSTRARQSFP------GPRQPNG 391
GP G S P P G+ + P LP Q P GP P G
Sbjct: 846 GPPGLPGTTSLFTPHPRMPGEQGPKGE----KGDPGLPGEPGLQGRPGELGPQGPTGPPG 901
Query: 392 AQDWRRADSLPRPQG 406
A+ A P G
Sbjct: 902 AKGQEGAHGAPGAAG 916
Score = 38.1 bits (87), Expect = 0.016
Identities = 80/323 (24%), Positives = 96/323 (29%), Gaps = 59/323 (18%)
Query: 114 APGAGEAEGLPEGTQAAGP-APAGKEHRKQDAETPPPPDPPAPETLLAP----------- 161
+PG+ G P GP PAG++ + PP P +LL+P
Sbjct: 1061 SPGSRGLPGFP------GPQGPAGRDGAPGNPGERGPPGKPGLSSLLSPGDINLLAKDVC 1114
Query: 162 ---PPLP-------------STPDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERM 205
PP P P P RE P L P ER
Sbjct: 1115 NDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERG 1174
Query: 206 AGNEALSPTSPFREGRPGEWRTPAARGP--------RSGDPG----PGPSHPAQPKAPRF 253
A E G PG P GP +G PG PG P P+ P
Sbjct: 1175 ADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSG 1234
Query: 254 PSNIIVTNG-AAREPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPGGGSS 312
I G R+ + E G G GD+G P G S
Sbjct: 1235 LPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESG 1294
Query: 313 PERVARGRGLPG----PAESLRAGGQAPRGPALANGFPSAHEALKSAPSSFAPAGKSLCF 368
+ GLPG + G Q PRGP NG P + + PS S
Sbjct: 1295 AMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPG--EPGPSGTPGQKGSKGE 1352
Query: 369 RPGPALPSTRARQSFPGPRQPNG 391
P LP F GPR P G
Sbjct: 1353 NGSPGLP------GFLGPRGPPG 1369
Score = 37.7 bits (86), Expect = 0.021
Identities = 71/302 (23%), Positives = 95/302 (31%), Gaps = 56/302 (18%)
Query: 124 PEGTQAAGPAPAGKEHRKQDAETPPPPDPPAPETLLAPPPLPSTPDPPRRELRAPSPPVE 183
P G A P + +D +T P P P+ PP +P P + +P +
Sbjct: 1289 PRGESGAMGLPGQEGLPGKDGDTGPT-GPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQK 1347
Query: 184 HPRLLRSVPTPLVMAQKISERMAGNEALSPTSPFREGRPGEWRTPAARGPRS-----GDP 238
+ P + + R E P +EG PG+ P +G R GD
Sbjct: 1348 GSKGENGSPG---LPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDK 1404
Query: 239 GPGPSHPAQPKAPRFPSNIIVTNGAAREPRRTLSRAAVSVQERRAQVLATIHGHAGAFPA 298
GP P QP P P + GH G
Sbjct: 1405 GP-PGGKGQPGDPGIPGH---------------------------------KGHTGLMGP 1430
Query: 299 AGDAGEGAPGGGSSPERVARGRGLPGPA---ESLRAGGQAPRGP--------ALANGFPS 347
G GE P G P GL G + E+LR Q G LA P+
Sbjct: 1431 QGLPGENGPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLETRLAYLLAQMPPA 1490
Query: 348 AHEALKSAPSSFAPAGK-SLCFRPGP-ALPSTRARQSFPGPRQPNGAQDWRRADSLPRPQ 405
++ + P P GK L R GP P + GP P G + R A P
Sbjct: 1491 YMKSSQGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAKGDPGAP 1550
Query: 406 GI 407
G+
Sbjct: 1551 GV 1552
Score = 36.6 bits (83), Expect = 0.046
Identities = 89/344 (25%), Positives = 112/344 (32%), Gaps = 71/344 (20%)
Query: 115 PGAGEAEGLPE--GTQAAGPAPAGKEHR-------KQDAETPPPPDPPA----PETLLAP 161
PG + GLP GT+AA G E+ K D P P P P +A
Sbjct: 989 PGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGVAG 1048
Query: 162 PPLPSTPDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGNEALSPTSPFREGR 221
PP PS P + SP R L P P + AG + +P +P G
Sbjct: 1049 PPGPSGPPGDKG-----SPG---SRGLPGFPGP--------QGPAGRDG-APGNPGERGP 1091
Query: 222 PGEWRTPAARGPRS---------GDPGPGPSHPAQPKAPRFPSNIIVTNGAAREPRRTLS 272
PG+ + P D PGP P P P F + V RE
Sbjct: 1092 PGKPGLSSLLSPGDINLLAKDVCNDCPPGP--PGLPGLPGFKGDKGVPGKPGREGTEGKK 1149
Query: 273 RAAVSVQERRAQVLATIHGHAGAFPAAGDAGE-------------GAPGGGSSP--ERVA 317
A +A G G A G+ G+ G PG P + +A
Sbjct: 1150 GEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIA 1209
Query: 318 RGRGLPGPAESL-RAGGQAPRGPALANGFPSAH--EALKSAPSSFAPAGKSLCFRPG-PA 373
G PG S + G P+GP+ G P E P GK+ PG P
Sbjct: 1210 GAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDGKPGPPGEPGKA--GEPGLPG 1267
Query: 374 LPSTRARQSF---------PGPRQPNGAQDWRRADSLPRPQGIT 408
R F PGPR +GA + LP G T
Sbjct: 1268 PEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDT 1311
Score = 35.8 bits (81), Expect = 0.078
Identities = 70/280 (25%), Positives = 90/280 (32%), Gaps = 55/280 (19%)
Query: 115 PGAGEAEGLPEGTQAAGPAPAGKEHRKQDAETPPPPDPPAPETLLAPPPLPSTPDPPRRE 174
PG A+G+ A P G + +P PP P+ P LP P +E
Sbjct: 1200 PGPPGADGI-----AGAAGPPGIQG------SPGKEGPPGPQ---GPSGLPGIPGEEGKE 1245
Query: 175 LR--APSPPVEHPRLLRSVPTPLVMAQKISERMAGNEALSPTSPFREGRPGEWRTPAARG 232
R P PP E P P + G+ S +P G G P G
Sbjct: 1246 GRDGKPGPPGE-PGKAGEPGLPGPEGARGPPGFKGHTGDSG-APGPRGESGAMGLPGQEG 1303
Query: 233 PRSGDPGPGPSHPAQPKAPRFPSNIIVTNGAAREPRRTLSRAAVSVQERRAQVLATIHGH 292
D GP+ P P+ PR P + G+ EP G
Sbjct: 1304 LPGKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEP-----------------------GP 1340
Query: 293 AGAFPAAGDAGE-GAPG--GGSSPERVARGRGLPG-PAESLRAGGQAPRGPALANGFPSA 348
+G G GE G+PG G P RG PG P E G + G GF
Sbjct: 1341 SGTPGQKGSKGENGSPGLPGFLGP------RGPPGEPGEKGVPGKEGVPGKPGEPGFKGE 1394
Query: 349 HEALKSAPSSFAPAGKSLCFRPG-PALPSTRARQSFPGPR 387
P GK +PG P +P + GP+
Sbjct: 1395 RGDPGIKGDKGPPGGKG---QPGDPGIPGHKGHTGLMGPQ 1431
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 55.8 bits (133), Expect = 7e-08
Identities = 85/343 (24%), Positives = 128/343 (37%), Gaps = 63/343 (18%)
Query: 92 PSLEESTSSPSE---PEDVIDLVQPAPGAGEAEGLPEGTQ----AAGPAPAGKEHRKQDA 144
PSL+ ++P P + + P+P G A P+G A P+P G
Sbjct: 1272 PSLKGGLATPPHKGAPNPAV-VTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPK 1330
Query: 145 ETPPPPD--PPAPETLLAPPPLPSTPDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKIS 202
P PP PP+P+ P LP+T + PS + PTP +
Sbjct: 1331 GAPTPPAVTPPSPK---GTPTLPATTPSSKGGPTTPSS--------KEGPTP----PAAT 1375
Query: 203 ERMAGNEALSPTSPFREGRPGEWRTPAARGPRSGDPGPGPSHPAQPKAPRFPSNIIVTNG 262
G A++P SP R PA P+ GDP P PK + P+ + G
Sbjct: 1376 PSHKGGPAMTPPSP--------KRGPAIPSPK-GDPTSPAVIPLSPK--KAPATPVTREG 1424
Query: 263 AAREPRRTLSRAAVS-VQERRAQVLATIHGHAGAFPAAGD-----AGEGAPGGGSSPERV 316
AA + L+ AV+ V ++A + G + GD +P +P++V
Sbjct: 1425 AATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQV 1484
Query: 317 ARGRGLPGPAESLRAGGQAPRGPALANGFPSAHEALKSAPSS----FAP----------- 361
A P A + A AP PA+ PS+ + + + PSS AP
Sbjct: 1485 ATSSS-PKKAPATPAPMGAPTLPAV---IPSSPKEVPATPSSRRDPIAPTATLLSKKTPA 1540
Query: 362 --AGKSLCFRPGPALPSTRARQSFPGPRQPNGAQDWRRADSLP 402
A K P +PS + + P P++ + A S P
Sbjct: 1541 TLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPP 1583
Score = 52.4 bits (124), Expect = 8e-07
Identities = 78/320 (24%), Positives = 104/320 (32%), Gaps = 45/320 (14%)
Query: 99 SSPSEPEDVIDLVQPAPGAGEAEGLPEGTQAAGPAPAGKEHRKQDAETP--------PPP 150
SSP P + L + + ++ P T + P P+ K A TP PP
Sbjct: 825 SSPVSPVEASFLPENSLSFQGSKDSPATTHSPTP-PSPKGAPTPSAVTPLSPKGVTLPPK 883
Query: 151 DPPAPETLLAPPPLPSTPDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGNEA 210
+ P P + P P P ++ A S P+ R+ P P +
Sbjct: 884 ETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGI------------- 930
Query: 211 LSPTSPFREGRPGEWRTPAARGPRSGDPGPGPSHPAQPKAPRFPSNIIVTNGAAREPRRT 270
P SP +G P TP A P S P GP+ P+ AP P AA P
Sbjct: 931 --PASPSPKGAP----TPPAATPPS--PKGGPATPSPKWAPTPP--------AATPPSPK 974
Query: 271 LSRAAVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPGGGSSPERVARGRGLPGPAESLR 330
A S + AT G G P + P P P +
Sbjct: 975 GGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAST 1034
Query: 331 AGGQAPRGPALANGFPSAHEALKSAPSSFAPAGKSLCFRPGPALPSTRARQSFPG--PRQ 388
P P G P+A K AP++ PA + GPA PS + + P P
Sbjct: 1035 PPAATPPSP---KGSPAATPLPKGAPTT--PAATLPSPKGGPATPSLKGAPTPPAATPPS 1089
Query: 389 PNGAQDWRRADSLPRPQGIT 408
P G P P T
Sbjct: 1090 PKGGPATPSPKGAPMPPAAT 1109
Score = 48.9 bits (115), Expect = 9e-06
Identities = 82/352 (23%), Positives = 115/352 (32%), Gaps = 42/352 (11%)
Query: 91 SPSLEESTSSPSEPEDVIDLVQPAPGAGEAEGLPEGTQAAGPAPAGKEHRKQDAETPPPP 150
+P+L ++SSP + + P + +G P A P+P G P PP
Sbjct: 908 APALSMTSSSPKKAR-ATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPP 966
Query: 151 D---------PPAPETLLAPPPLPSTPDPPR------RELRAPSPPVEHPRLLRSVPTPL 195
P P AP P +TP P+ AP+PP P + P
Sbjct: 967 AATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAAT 1026
Query: 196 VMAQKISERMAGNEALSPTSPFREGRP-GEWRTPAARGPRSGDPGPGPSHPAQPKAPRFP 254
+ S A SP P G TPAA P P GP+ P+ AP P
Sbjct: 1027 PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLP---SPKGGPATPSLKGAPTPP 1083
Query: 255 SNIIVT---NGAAREPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAA------GDAGEG 305
+ + A P+ A + + + H A PAA G
Sbjct: 1084 AATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATP 1143
Query: 306 APGG-----GSSPERVARGRGLPGPAESLRAGGQAPRGPALANGFPSAHEALKSAPSSFA 360
P G ++P G P P + P P PS A + P++
Sbjct: 1144 PPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGA-PTTPAATP 1202
Query: 361 PAGKSLCFRPGPALPSTRARQSFPGPR------QPNGAQDWRRADSLPRPQG 406
P+ K P P T + P P+ P GA A + P P+G
Sbjct: 1203 PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT-TPAATPPSPKG 1253
Score = 47.0 bits (110), Expect = 3e-05
Identities = 75/317 (23%), Positives = 108/317 (34%), Gaps = 37/317 (11%)
Query: 100 SPSEPEDVIDLVQPAPGAGEAEGLPEGTQAAGPAPAGKEHRKQDAETPPPP--DPPAPET 157
+P+ P + + P +G P A P+P G P PP PP+P+
Sbjct: 1056 APTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKG 1115
Query: 158 LLAPPPLPSTPDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGNEALSPTSPF 217
LA PP P P +P + P + TP +A +P
Sbjct: 1116 GLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLA--------TPP 1167
Query: 218 REGRPGEWRTPAAR--GPRSGDPGPGP-SHPAQPKA-PRFPSNIIVTNGAAREPRRTLSR 273
+G P TPAA P+ G P P P P A P P + T P+ +
Sbjct: 1168 PKGAP---TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT----PSPKGAPTT 1220
Query: 274 AAVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPGGGSSPERVARGRGLPGP----AESL 329
A + + + A PAA GG ++P +G P P SL
Sbjct: 1221 PAATPPSPKGGLATPSPKGAPTTPAA--TPPSPKGGPATPP----PKGAPTPPAATPPSL 1274
Query: 330 RAGGQAPRGPALANGFPSAHEALKSAPSSFAPAGKSLCFRPGPALPSTRARQSFPGPRQP 389
+ G P N + K P++ P G P P + + + PG P
Sbjct: 1275 KGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKG-----APTPPAATPPSPKGSPGTPPP 1329
Query: 390 NGAQDWRRADSLPRPQG 406
GA A + P P+G
Sbjct: 1330 KGAPT-PPAVTPPSPKG 1345
Score = 43.1 bits (100), Expect = 5e-04
Identities = 77/328 (23%), Positives = 113/328 (34%), Gaps = 48/328 (14%)
Query: 91 SPSLEESTSSPSEPEDVIDLVQP-----APGAGEAEGLPEGTQAAG---------PAPAG 136
+P E ++PS+ + V P AP +G P + G P+P
Sbjct: 1418 TPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKE 1477
Query: 137 KEHRKQDAETPPPPDPPAPETLLAPPPLPST-PDPPRRELRAPSPPVEHPRLLRSVPTPL 195
KQ A + P PA + P LP+ P P+ PS R PT
Sbjct: 1478 PPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPS-----SRRDPIAPTAT 1532
Query: 196 VMAQKISERMAGNEALSPTSPFREGRPGEWRTPAARGPRSGDPGPGPSHPAQPKAPRFPS 255
++++K +A EAL P + P +TPA P+ P+ P+ +A P+
Sbjct: 1533 LLSKKTPATLAPKEALIPPA---MTVPSPKKTPAIPTPKE-----APATPSSKEASSPPA 1584
Query: 256 NIIVTNGAAREPRRTLSRAAV-SVQERRAQVLATIHGHAGAFPAAGDAGEGAP------- 307
T A P+ L AV S + A + + A A +G P
Sbjct: 1585 VTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTP 1644
Query: 308 ----GGGSSPERVARGRGLPGPAESLRAGGQAPRGP-----ALANGFPSAHEALKSAPSS 358
+SP V G P S G A +GP L P + + +AP+
Sbjct: 1645 SSLKDSPTSPASVTCKMGATVPQAS--KGLPAKKGPTALKEVLVAPAPESTPII-TAPTR 1701
Query: 359 FAPAGKSLCFRPGPALPSTRARQSFPGP 386
P K P P A+ GP
Sbjct: 1702 KGPQTKKSSATSPPICPDPSAKNGSKGP 1729
Score = 42.7 bits (99), Expect = 6e-04
Identities = 77/317 (24%), Positives = 110/317 (34%), Gaps = 36/317 (11%)
Query: 91 SPSLEESTSSPSEPEDVIDLVQPAPGAGEAEGLPEGTQAAGPAPAGKEHRKQDAETPPPP 150
+P + +S SPS P PG + +G+ + A A + KE +D+
Sbjct: 727 APEIPKSVPSPSLPP-----AGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATA 781
Query: 151 DPPAPETLLA--PPPL-----PSTPDPPRRELRA-PSPPVEHPRLLRSVPTPLVMAQKIS 202
T LA P PL P T PP ++ A P P+ + S P V A +
Sbjct: 782 SSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGN----LSSPVSPVEASFLP 837
Query: 203 ERMAGNEALSPTSPFREGRPGEWRTPAARGPRSGDPGPGPSHPAQPKAPRFPSNIIVTNG 262
E + + P +P P+ G P P P PK P T
Sbjct: 838 ENSLSFQG-------SKDSPATTHSPTPPSPK-GAPTPSAVTPLSPKGVTLPPKETPTPS 889
Query: 263 AAREPRRTLSRAAVSVQERRA-QVLATIHGHAGAFPA-AGDAGEGAPGGGSSPERVARGR 320
P A + ++ A + ++ A A PA G +P G +P
Sbjct: 890 VVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPS 949
Query: 321 GLPGPAESLRAGGQAPRGPALANGFPSAHEAL---KSAPSSFAPAGKSLCFRPGPALPST 377
GPA + AP PA P A K AP+ PA + GPA PS
Sbjct: 950 PKGGPATP--SPKWAPTPPAATPPSPKGGPATPSPKGAPT--PPAATPPSPKGGPATPSP 1005
Query: 378 RARQSFPG--PRQPNGA 392
+ + P P P G+
Sbjct: 1006 KGAPTPPAVTPPSPKGS 1022
Score = 30.0 bits (66), Expect = 4.3
Identities = 36/115 (31%), Positives = 42/115 (36%), Gaps = 12/115 (10%)
Query: 113 PAPGAGEAEGLPEGTQAAGPA-PAGKEHRK----QDAETPP-----PPDPPAPETLLAPP 162
P P A P T A P P K+ K +DA P PP+ A L A
Sbjct: 1718 PDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAA 1777
Query: 163 PLPSTPDPPRRELRA-PSPPVEHPRLLRSVPTPLVMAQKISERMAGNEALSPTSP 216
P P + A PSPPV P VPT L Q+ G SP+ P
Sbjct: 1778 FEKVLPKPESASVSAAPSPPVSLPLAPSPVPT-LPPKQQFLPSSPGLVLESPSKP 1831
>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
Length = 1295
Score = 55.5 bits (132), Expect = 1e-07
Identities = 61/214 (28%), Positives = 80/214 (37%), Gaps = 30/214 (14%)
Query: 91 SPSLEESTSSPSEPEDVIDLVQPAPGAGEAEGLPEGTQAAGPAPAGKEHRKQDAETPPPP 150
SP++ E PS P PG A+ P Q A P P + + + PPPP
Sbjct: 1053 SPTISEGPV-PSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPP 1111
Query: 151 DPPAPETLLAP---PPLPS---TPDPPRRELRAPSPP--VEHPRLLRSVPTPLVMAQKIS 202
P AP T AP PP PS +P P R+E AP P + RS P+P A
Sbjct: 1112 RPVAPPTRPAPPQRPPPPSGARSPAPTRKEFGAPKSPGTTRKDNIGRSQPSP--QAGLAG 1169
Query: 203 ERMAGNEALSPTSPFREG---------RPGEWRTPAARGPRSGDPGPGPSHPAQPKAPRF 253
AG PT P R G R R ++ + G + +P P+
Sbjct: 1170 PGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQ- 1228
Query: 254 PSNIIVTNGAAREPRRTLSRAAVSVQERRAQVLA 287
AA P+ +L A +QE V A
Sbjct: 1229 ---------AAFPPQSSLPPPAQRLQEPLVPVAA 1253
Score = 30.0 bits (66), Expect = 4.3
Identities = 27/104 (25%), Positives = 38/104 (36%), Gaps = 14/104 (13%)
Query: 105 EDVIDLVQPAPGAGEAEGLPEGTQAAGPA--------PAGKEHRKQDAETPPPP------ 150
+D I QP+P AG A P G A P A + H + A P
Sbjct: 1153 KDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTS 1212
Query: 151 DPPAPETLLAPPPLPSTPDPPRRELRAPSPPVEHPRLLRSVPTP 194
+ T L P P PP+ L P+ ++ P + + P P
Sbjct: 1213 ETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMP 1256
>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
Length = 1612
Score = 55.5 bits (132), Expect = 1e-07
Identities = 52/194 (26%), Positives = 78/194 (40%), Gaps = 17/194 (8%)
Query: 91 SPSLEESTSSPSEPEDVIDLVQPAPGAGEAEGLPEGTQAAGPAPAGKEHRKQDAETPPPP 150
SP++ E PS P PG A+ P Q A P P + + + PPPP
Sbjct: 1092 SPTISEGPV-PSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPP 1150
Query: 151 DPPAPETLLAPPPLPSTPDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGNEA 210
P AP T APP P PP R+P+P + + + P+P V A E
Sbjct: 1151 RPVAPPTRPAPPQRP----PPPSGARSPAPTRKEFGGIGAPPSPGV---------ARREM 1197
Query: 211 LSPTSPFREGRPGEWRTPAARGPRSGDPGPGPSHPAQPKAPRFPSNIIVTNGAAREPRRT 270
+P SP + R+ + P++G GPGP+ + + P P V + R +
Sbjct: 1198 EAPKSPGTTRKDNIGRSQPS--PQAGLAGPGPAGYSTAR-PTIPPRAGVISAPQSHARAS 1254
Query: 271 LSRAAVSVQERRAQ 284
R Q + ++
Sbjct: 1255 AGRLTPESQSKTSE 1268
Score = 32.0 bits (71), Expect = 1.1
Identities = 33/130 (25%), Positives = 47/130 (36%), Gaps = 19/130 (14%)
Query: 84 GGVCCLCSPSL-EESTSSPSEP----EDVIDLVQPAPGAGEAEGLPEGTQAAGPA----- 133
GG+ SP + +P P +D I QP+P AG A P G A P
Sbjct: 1182 GGIGAPPSPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRA 1241
Query: 134 ---PAGKEHRKQDAETPPPP------DPPAPETLLAPPPLPSTPDPPRRELRAPSPPVEH 184
A + H + A P + T L P P PP+ L P+ ++
Sbjct: 1242 GVISAPQSHARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQE 1301
Query: 185 PRLLRSVPTP 194
P + + P P
Sbjct: 1302 PLVPVAAPMP 1311
>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
Length = 1499
Score = 55.5 bits (132), Expect = 1e-07
Identities = 102/400 (25%), Positives = 127/400 (31%), Gaps = 99/400 (24%)
Query: 72 LDEDFEEPVLCDGGVCCLCSPSLEESTSSPSEPEDVIDLVQPAPGAGEAEGLPEGTQAAG 131
L+ D +P C C+C E +DV+D P GE + T G
Sbjct: 49 LNRDIWKPAPCQ---ICVCDNGA--ILCDKIECQDVLDCADPVTPPGECCPVCSQTPGGG 103
Query: 132 PAPAGKEHRKQDAE----------------TPPP--------------PDPPAPETLLAP 161
G+ + Q E PP P P P+ +
Sbjct: 104 NTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGE 163
Query: 162 PPLPSTPDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGNEALSPTSPFREGR 221
P +P P AP PP HP S P P +++ S +MAG + S
Sbjct: 164 PGVPGQPG-------APGPP-GHP----SHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLM 211
Query: 222 PGEWRTPAARGPRS--------------GDPG-PGPSHPAQPKAPRFPSNIIVTNGAARE 266
PG RGP+ G+PG PGP P + P P G E
Sbjct: 212 PGSVGPVGPRGPQGLQGQQGGAGPTGPPGEPGDPGPMGPIGSRGPEGPPG---KPGEDGE 268
Query: 267 PRRTLSRAAVSVQER-------RAQVLATIHGHAGAFPAAGDAGE-GAPG----GGSSPE 314
P R + V A L + GH G G GE GAPG G +
Sbjct: 269 PGRNGNPGEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGP 328
Query: 315 RVARG----RGLPGPAESLRAGGQAPRGPALANGFPSAHEALKSAPSSFAPAGKSLCFRP 370
A G RG+PG E R G Q G A+G P P P G P
Sbjct: 329 MGAMGPLGPRGMPG--ERGRLGPQGAPGQRGAHGMP-------GKPGPMGPLG-----IP 374
Query: 371 G----PALPSTRARQSFPGPRQPNGAQDWRRADSLPRPQG 406
G P P + G R P G Q R P P G
Sbjct: 375 GSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVG 414
Score = 48.1 bits (113), Expect = 2e-05
Identities = 55/231 (23%), Positives = 75/231 (32%), Gaps = 15/231 (6%)
Query: 207 GNEALSPTSPFREGRPGEWRTPAARGPR-----SGDPGP--------GPSHPAQPKAPRF 253
G L P GRPG P ++GPR G PGP P P QP AP
Sbjct: 116 GEPGLVPVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGP 175
Query: 254 PSNIIVTNGAAREPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPGGGSSP 313
P + + A + + + + G G G G GG+ P
Sbjct: 176 PGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQQGGAGP 235
Query: 314 ERVARGRGLPGPAESLRA-GGQAPRGPALANGFPSAHEALKSAPSSFAPAGKSLCFRPG- 371
G PGP + + G + P G +G P + + +P + PG
Sbjct: 236 TGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGL 295
Query: 372 PALPSTRARQSFPGPRQPNGAQDWRRADSLPRPQGITVQFAGRGSSEEARR 422
P L R + GP+ GA + P G RG E R
Sbjct: 296 PGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGR 346
Score = 47.8 bits (112), Expect = 2e-05
Identities = 61/212 (28%), Positives = 72/212 (33%), Gaps = 32/212 (15%)
Query: 220 GRPGEWRTPAARGPRSGDPGPGPSHPAQPKAPRFPSNIIVTNGAAREPRRTLSRAAVSVQ 279
G PG TP GP GP P P P G A AV +
Sbjct: 1008 GLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGER 1067
Query: 280 ERRAQV-LATIHGHAGA------FPAAGDAGE-GAPG--GGSSPERVARGRGLPGP---- 325
R A + G GA A GDAG+ G PG G P A RGLPGP
Sbjct: 1068 GDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQGPR 1127
Query: 326 AESLRAGGQAPRGPALANGF-----------PSAHEALKSAPSSFAPAGKSLCFRPGPAL 374
+ G + RG GF P+ + P F P G PGP
Sbjct: 1128 GDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGP-----PGPVG 1182
Query: 375 PSTRARQSFPGPRQPNGAQDWRRADSLPRPQG 406
PS ++ PGP P G R + P+G
Sbjct: 1183 PS--GKEGNPGPLGPIGPPGVRGSVGEAGPEG 1212
Score = 38.5 bits (88), Expect = 0.012
Identities = 56/219 (25%), Positives = 74/219 (33%), Gaps = 39/219 (17%)
Query: 215 SPFREGRPGEWRTPAARGPRSGDPG----PGPSHPAQPKAPRFPSNIIVTNGAAREPRRT 270
SP G G TP A+GP +G PG PG + P P+ + G +P
Sbjct: 415 SPGLPGAIGTDGTPGAKGP-TGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVP 473
Query: 271 LSRAAVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPGG--------GSSPERVARGR-- 320
+ + HG G G+ G+ P G G ER A G
Sbjct: 474 GFKGEAGPKGEPGP-----HGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRG 528
Query: 321 -----GLPGPAESLRAGGQAPRGPALANGFPSAHEALKSAPSS-FAPAGKSLCFRPGPAL 374
GLPGP G Q RGP ++G P + P P + L PG
Sbjct: 529 FPGSDGLPGP-----KGAQGERGPVGSSG-PKGSQGDPGRPGEPGLPGARGLTGNPGVQG 582
Query: 375 PSTR-------ARQSFPGPRQPNGAQDWRRADSLPRPQG 406
P + PGP G + + LP P+G
Sbjct: 583 PEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGPKG 621
Score = 38.5 bits (88), Expect = 0.012
Identities = 78/328 (23%), Positives = 106/328 (32%), Gaps = 51/328 (15%)
Query: 115 PGAGEAEGLPEGTQAAG-PAPAGKEHRKQDAETPPPPDPPAPETLLAPPPLPSTP----- 168
PGA +G P G P +G +P P P+ + P P P
Sbjct: 419 PGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGE 478
Query: 169 -----DPPRRELRAP--SPPVEHPRLLRSVPTPLVMAQKISERMAGNEALSPTS---PFR 218
+P ++ P P E R R P + + ER A P S P
Sbjct: 479 AGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGP 538
Query: 219 EGRPGEWRTPAARGPRSGDPGPG-PSHPAQPKAPRFPSNIIVTN--------GAAREPRR 269
+G GE + GP+ PG P P P A N V GA E R
Sbjct: 539 KGAQGERGPVGSSGPKGSQGDPGRPGEPGLPGARGLTGNPGVQGPEGKLGPLGAPGEDGR 598
Query: 270 TLSRAAVSVQERRAQV-LATIHGHAGAFPAAGDAGE-------GAPG--------GGSSP 313
++ ++ + + L G +G G+AG GAPG G P
Sbjct: 599 PGPPGSIGIRGQPGSMGLPGPKGSSGDPGKPGEAGNAGVPGQRGAPGKDGEVGPSGPVGP 658
Query: 314 ERVARGRGLPGPAESLRAGG-QAPRGPALANGFPSAHEALKSAPSSFAPAG-KSLCFRPG 371
+A RG GP G P GP G P + + P + P G + PG
Sbjct: 659 PGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKP-GDQGVPGDPGAVGPLGPRGERGNPG 717
Query: 372 -------PALPSTRARQSFPGPRQPNGA 392
LP + GP P G+
Sbjct: 718 ERGEPGITGLPGEKGMAGGHGPDGPKGS 745
Score = 37.0 bits (84), Expect = 0.035
Identities = 75/303 (24%), Positives = 93/303 (30%), Gaps = 51/303 (16%)
Query: 122 GLP-EGTQAAGPAPAGKEHRKQDAETPPPPDPPAPETLLAPPPLPSTPDPPRRELRAPSP 180
GLP E A G P G + + TP PP + + + TP P
Sbjct: 726 GLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPKGDRGG---- 781
Query: 181 PVEHPRLLRSVPTPLVMAQKISERMAGNEALSPTSPFREGRPGEWRTPAARGPRSGDPGP 240
+ +K +E AGN+ G PG P GP P
Sbjct: 782 ----------------IGEKGAEGTAGNDGA-------RGLPGPLGPPGPAGPTGEKGEP 818
Query: 241 GPSHPAQPKAPRFPSNIIVTNGAAREPRRTLSRAAVSVQERRAQVLATI-----HGHAGA 295
GP P R NG P + A + + V G AG+
Sbjct: 819 GPRGLVGPPGSRGNPGSRGENG----PTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGS 874
Query: 296 FPAAGDAGEGAPGGGSSPERVARGRGLPGPAESL----RAGGQAPRGPALANGFPSA--H 349
G AG P G + + GRG GP + AG P GPA A G P+
Sbjct: 875 PGPQGLAGSPGPHGPNGVPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGAPG-PAGPLG 933
Query: 350 EALKSAPSSFA--PAGKSLCFRPGPALPSTRARQSFPGPRQPNGAQDWRRADSLPRPQGI 407
E K P P GPA P PG + G D P P G
Sbjct: 934 EPGKEGPPGLRGDPGSHGRVGDRGPAGP-----PGGPGDKGDPGEDGQPGPDGPPGPAGT 988
Query: 408 TVQ 410
T Q
Sbjct: 989 TGQ 991
Score = 33.1 bits (74), Expect = 0.51
Identities = 52/213 (24%), Positives = 65/213 (30%), Gaps = 29/213 (13%)
Query: 213 PTSPFREGRPGEWRTPAARGPRSGDPGPGPSHPAQPKAPRFPSNIIVTNGAAREPRRTLS 272
P +P G G GP+ PG A P P + G E R
Sbjct: 290 PGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGP 349
Query: 273 RAAVSVQERRAQVLATIHGHAG--------AFPA-AGDAGEGAPGGGSSPERVARGRGLP 323
+ A +R A + G G FP G GE P G PE RG
Sbjct: 350 QGAPG--QRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGET 407
Query: 324 GPAESLRAGGQAPRGPALANGFPSAHEALKSAPSSFAPAGKSLCFRPGPA-LPSTRARQS 382
GP GP + G P A P + P G PG + P +
Sbjct: 408 GPP-----------GPVGSPGLPGA-IGTDGTPGAKGPTGS-----PGTSGPPGSAGPPG 450
Query: 383 FPGPRQPNGAQDWRRADSLPRPQGITVQFAGRG 415
PGP+ G Q R P G + +G
Sbjct: 451 SPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKG 483
Score = 29.6 bits (65), Expect = 5.6
Identities = 41/142 (28%), Positives = 48/142 (33%), Gaps = 12/142 (8%)
Query: 112 QPAP-GAGEAEGLPEGTQAAG-------PAPAGKEHRKQDAETPPPPDPPAPETLLAPPP 163
+P P G +G P A G P PAG + TP P P P
Sbjct: 1045 EPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPG 1104
Query: 164 LPSTPDPPRRELRAPSPPVEHPRLLRSVPTPL-VMAQKISERMAGNEALSPTSPFREGRP 222
PP R + P + PR + QK G + L P P G
Sbjct: 1105 SRGPIGPPGRAGKRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGL-PGPPGPNGEQ 1163
Query: 223 GEWRTPAARGPRSGDPGP-GPS 243
G P GPR G PGP GPS
Sbjct: 1164 GSAGIPGPFGPR-GPPGPVGPS 1184
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 55.5 bits (132), Expect = 1e-07
Identities = 73/273 (26%), Positives = 88/273 (32%), Gaps = 50/273 (18%)
Query: 109 DLVQPAPGAGEAEGLPEGTQAAGPAPAGKEHRKQDAETPP-PPDPPAPETLLAPPPLPST 167
D P PG G L + GP P Q PP PP PP + PP P
Sbjct: 30 DFRSPPPGMG----LNQNRGPMGPGPG------QSGPKPPIPPPPPHQQQQQPPPQQPPP 79
Query: 168 PDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMAGNEALSPTSPFREGRPGEWRT 227
PP + PP P + P P + S + + P P
Sbjct: 80 QQPPPHQ----PPPHPQPHQQQQPPPP----PQDSSKPVVAQGPGPAPGVGSAPPASSSA 131
Query: 228 PAARGPRSGDP---GPGPSHPAQPKAPRFPSNIIVTNGAAREPRRTLSRAAVSVQERRA- 283
P A P SG P GPGP+ P P A VT+ P T + V +A
Sbjct: 132 PPATPPTSGAPPGSGPGPT-PTPPPA--------VTSAPPGAPPPTPPSSGVPTTPPQAG 182
Query: 284 ---QVLATIHGHAGAFPAAGDAGEGAPGGGSSPERVARGRGLPGPAESLRAGGQAPRGPA 340
A + G G P G G G P GG P G PG L G P+ P
Sbjct: 183 GPPPPPAAVPG-PGPGPKQG-PGPGGPKGGKMP-----GGPKPGGGPGLSTPGGHPKPPH 235
Query: 341 LANG--------FPSAHEALKSAPSSFAPAGKS 365
G P H+ P P G+S
Sbjct: 236 RGGGEPRGGRQHHPPYHQQHHQGPPPGGPGGRS 268
Score = 41.6 bits (96), Expect = 0.001
Identities = 44/166 (26%), Positives = 52/166 (31%), Gaps = 28/166 (16%)
Query: 92 PSLEESTSSPSEPED-----VIDLVQPAPGAGEAEGLPEGTQAAGPAPAGKEHRKQDAET 146
P + P P+D V PAPG G A A P +G T
Sbjct: 91 PQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPT 150
Query: 147 PPPPDPPAPETLLAPPPLPSTPDPPRRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMA 206
P PP APPP P + P +A PP + P P
Sbjct: 151 PTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGPGP------------ 198
Query: 207 GNEALSPTSPFREGRPGEWRTPAARGPRSGDPGPGPSHP-AQPKAP 251
+ P P PG GP+ G GPG S P PK P
Sbjct: 199 -KQGPGPGGPKGGKMPG--------GPKPGG-GPGLSTPGGHPKPP 234
>gi|18079216 CASK interacting protein 1 [Homo sapiens]
Length = 1431
Score = 55.1 bits (131), Expect = 1e-07
Identities = 62/239 (25%), Positives = 86/239 (35%), Gaps = 42/239 (17%)
Query: 109 DLVQPAPGAGEAEGLPE----------GTQAAGPAPAGKEHRKQDAETPPPPDPPAPETL 158
D V+ P A E E PE GT PA ++ + PPPP P P L
Sbjct: 1146 DTVKRRPKAKEREAGPEPPPPLSVYHNGTGTVRRRPASEQAGPPELPPPPPPAEPPPTDL 1205
Query: 159 LAPPPLPSTPDPPRRELRAPSPPVEHPRLL----------------RSVPTPLVMAQKIS 202
PPLP PP E R P+ P P+ + + VP P + ++
Sbjct: 1206 AHLPPLP----PPEGEARKPAKPPVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVK 1261
Query: 203 ERMAGNEALSPTSPFREGRPGEWRTPAARGPRSGDPGPGPSHPAQP-----KAPRFPSNI 257
+SP P P + A S P P PS QP K P P ++
Sbjct: 1262 RAHGTPPPVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSL 1321
Query: 258 IVTNGAAREPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPGGGSSPERV 316
GA+ + A+ V + + A A A PA EGA G S+ +++
Sbjct: 1322 ----GASPAKPPSPGAPALHVPAKPPRAAAAAAAAAAAPPA---PPEGASPGDSARQKL 1373
Score = 49.7 bits (117), Expect = 5e-06
Identities = 65/244 (26%), Positives = 90/244 (36%), Gaps = 18/244 (7%)
Query: 149 PPDPPAPETLLAPPPLPSTPDPP--RRELRAPSPPVEHPRLLRSVPTPLVMAQKISERMA 206
P P E + PPL +R +RA E+ + + + + K ER A
Sbjct: 1100 PRGPSKGEAGVEGPPLAKVEASATLKRRIRAKQNQQENVKFILTESDTVKRRPKAKEREA 1159
Query: 207 GNEALSPTSPFREGRPGEWRTPAAR--GPRSGDPGPGPSHPAQPKAPRFPSNIIVTNGAA 264
G E P S + G R PA+ GP P P P+ P P + G A
Sbjct: 1160 GPEPPPPLSVYHNGTGTVRRRPASEQAGPPELPPPPPPAEPPPTDLAHLPP-LPPPEGEA 1218
Query: 265 REPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPGGGSSPERVARGRGLPG 324
R+P ++ VS + Q + + G P PG G SPE V R G P
Sbjct: 1219 RKP----AKPPVSPKPVLTQPVPKLQGS----PTPTSKKVPLPGPG-SPE-VKRAHGTPP 1268
Query: 325 P-AESLRAGGQAPRGPALANGFPSAHEALKSAPSSFAPAGKSLCFRPG--PALPSTRARQ 381
P + AP+ G PS APS +L PG P+L ++ A+
Sbjct: 1269 PVSPKPPPPPTAPKPVKAVAGLPSGSAGPSPAPSPARQPPAALAKPPGTPPSLGASPAKP 1328
Query: 382 SFPG 385
PG
Sbjct: 1329 PSPG 1332
Score = 38.9 bits (89), Expect = 0.009
Identities = 66/258 (25%), Positives = 82/258 (31%), Gaps = 53/258 (20%)
Query: 91 SPSLEESTSSPSEPEDVIDLVQPAPGAGEAEGLPEGTQA-AGPAPAGKEHRKQDAETPPP 149
+P L T P P L Q G A LP+ + GPA G PP
Sbjct: 807 TPQLLPPTERPMSPRS---LPQSPTHRGFAYVLPQPVEGEVGPAAPGPA---------PP 854
Query: 150 PDPPAPETLLAPPPLPSTPDPPR-------RELRAPSPPVEHPRLLRSVPTPLVMAQKIS 202
P P A TL PP + P P+ R + S P L+ + P Q+
Sbjct: 855 PVPTAVPTLCLPPEADAEPGRPKKRAHSLNRYAASDSEPERDELLVPAAAGPYATVQR-- 912
Query: 203 ERMAGNEALSPTSPFREGRPGEWRTPAAR----------GPRSGDPGPGPSHPAQPKAPR 252
R GR R PA R GP P P + +
Sbjct: 913 ---------------RVGRSHSVRAPAGADKNVNRSQSFAVRPRKKGPPPPPPKRSSSAL 957
Query: 253 FPSNIIVTNGAAREPRRTLSRAAVSVQERRAQVLA--TIHGHAGAFPAAGDAGE--GAPG 308
+N+ EP L V Q RRA LA G AG+ + E G
Sbjct: 958 ASANLADEPVPDAEPEDGL--LGVRAQCRRASDLAGSVDTGSAGSVKSIAAMLELSSIGG 1015
Query: 309 GGSSPERVARGRGLPGPA 326
GG + R G P PA
Sbjct: 1016 GGRAARRPPEGHPTPRPA 1033
Score = 36.6 bits (83), Expect = 0.046
Identities = 69/267 (25%), Positives = 89/267 (33%), Gaps = 63/267 (23%)
Query: 93 SLEESTSSPSEPEDVIDLVQPAPGAGEAEGLPEGTQAAGPAPAGKEHRKQDAET------ 146
SL +S SEPE LV A G G + APAG + +++
Sbjct: 882 SLNRYAASDSEPERDELLVPAAAGPYATVQRRVGRSHSVRAPAGADKNVNRSQSFAVRPR 941
Query: 147 ---PPPPDPPAPETLLAPPPLPSTPDPP----------RRELRAPSPPVEHPRLLRSVPT 193
PPPP P + LA L P P R + R S L SV T
Sbjct: 942 KKGPPPPPPKRSSSALASANLADEPVPDAEPEDGLLGVRAQCRRASD------LAGSVDT 995
Query: 194 PLVMAQKISERMAGNEALSPTSPFREGRPGEWRTPAARGPRSGDPGPGPSHPAQPKAPRF 253
+ K M L +S GR AAR P G P P P+ P +
Sbjct: 996 GSAGSVKSIAAM-----LELSSIGGGGR-------AARRPPEGHPTPRPASPEPGR---- 1039
Query: 254 PSNIIVTNGAAREPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPGGGSSP 313
+ T A+ + + + V RR T+ G P G G G S
Sbjct: 1040 ----VATVLASVKHKEAIGPGGEVVNRRR-----TLSG-----PVTGLLATARRGPGESA 1085
Query: 314 ERVARGRGLPGPAESLRAGGQAPRGPA 340
+ PGP G Q PRGP+
Sbjct: 1086 D--------PGPFVEDGTGRQRPRGPS 1104
Score = 32.3 bits (72), Expect = 0.86
Identities = 62/251 (24%), Positives = 74/251 (29%), Gaps = 65/251 (25%)
Query: 100 SPSEPEDV-IDLVQPAPGAGEAEGLPEGTQAA--GPAPAGKEHRKQDAETPP-------- 148
SP PE D P + L + QAA GPA G K + PP
Sbjct: 633 SPPPPEPTPADCQSPKMTTFQDSELSDELQAAMTGPAEVGPTTEKPSSHLPPTPRATTRQ 692
Query: 149 ---------------------PPDPPAP-----ETLLAPPPLPSTPDPPRRELRAPSPPV 182
PP P +P E LL P P TP RE R P
Sbjct: 693 DSSLGGRARHMSSSQELLGDGPPGPSSPMSRSQEYLLDEGPAPGTPP---REAR----PG 745
Query: 183 EHPRLLRSVPTPLVMAQKISERMAGNEALSPTSPFREGRPGEWRTPAARGPRSGDPGPGP 242
H ++ P V + G +P + RPG +P A G GP
Sbjct: 746 RHGHSIKRASVPPVPGKPRQVLPPGTSHFTPPQTPTKTRPG---SPQALG------GPHG 796
Query: 243 SHPAQPKAPRFPSNIIVTNGAAREPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAAGDA 302
PA K P + T P S A VL P G+
Sbjct: 797 PAPATAKVKPTPQLLPPT----ERPMSPRSLPQSPTHRGFAYVLPQ--------PVEGEV 844
Query: 303 GEGAPGGGSSP 313
G APG P
Sbjct: 845 GPAAPGPAPPP 855
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 55.1 bits (131), Expect = 1e-07
Identities = 86/287 (29%), Positives = 103/287 (35%), Gaps = 44/287 (15%)
Query: 110 LVQPAPGAGEAEGLPEGTQAAGPAPAGKEHRKQDAE-TPPPPDPPAPETLLAPPPLPSTP 168
+VQP P A A P G + G +P GK R ++E T PP P P L PPP P P
Sbjct: 205 VVQPVPPA--ALSGPSGEE--GLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPP 260
Query: 169 DPPRRELRAPSPPVE--HPRLLRSVP----TPLVMAQKISERMAGNEALS-----PTSPF 217
PP A SPP + P L ++ P ER +L P +
Sbjct: 261 PPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAPAY 320
Query: 218 REGRPGEWRTPAARGPRSGDPGPGPSHPAQPKAPRFPSNIIVTNGAAREPRRTLSRAAVS 277
PG PAA PGPGP P P A R P L +
Sbjct: 321 TAHPPGHRLVPAA------PPGPGPRPPGAESHGCLP--------ATRPPGSDLRES--R 364
Query: 278 VQERRAQVLATIHGHAGAFPAAGDAGEGAPG-GGSSPERVARGRGLPG--PAESLRAGGQ 334
VQ R + P A G PG SS + GL G P + G
Sbjct: 365 VQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGI-PGAD 423
Query: 335 APRGPALANGF-----PSAHEALKSAPSSFAPAG-KSLCFRPGPALP 375
+ PAL PSAH + K P APA L PGP+ P
Sbjct: 424 HYQTPALEVSHHGRLGPSAHSSRK--PFLGAPAATPHLSLPPGPSSP 468
Score = 51.6 bits (122), Expect = 1e-06
Identities = 86/318 (27%), Positives = 111/318 (34%), Gaps = 83/318 (26%)
Query: 72 LDEDFEEP----VLCDGGVCCLCSPSLEESTSSPSEPEDVIDLVQPAPGAGEA-----EG 122
L++ FEEP +L DG + L+ES E + V P P E
Sbjct: 678 LEDQFEEPAEFKILPDGLANIM--KMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSP 735
Query: 123 LPEGTQAAGPAPA-----------GKEHRKQDAETPPPPDPPAPETLLAPPPLPSTPDPP 171
P T APA +++ + PPP PP P PP PS P PP
Sbjct: 736 FPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPP--PSQPQPP 793
Query: 172 RRELRAPSPPVEHPRLLRSV---------------------PTPLVMAQKISERMAGNEA 210
P PP LL+S+ P PL Q +G A
Sbjct: 794 ------PPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATA 847
Query: 211 LSPTS--PFREGRP-------GEWRT---PAARGPRSG-DPGPGPSHPAQPKAPRFPSNI 257
L PTS P +G P ++ T P AR R+G +P PGP P QP P
Sbjct: 848 LPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPP------ 901
Query: 258 IVTNGAAREPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPGGGSSPERVA 317
+ P R+ S + R + L G + PA D + A S ER+
Sbjct: 902 -----LSLPPARSESEVLEEI-SRACETLVERVGRSATDPA--DPVDTAEPADSGTERL- 952
Query: 318 RGRGLPGPAESLRAGGQA 335
LP AGG A
Sbjct: 953 ----LPPAQAKEEAGGVA 966
Score = 41.6 bits (96), Expect = 0.001
Identities = 82/328 (25%), Positives = 105/328 (32%), Gaps = 93/328 (28%)
Query: 92 PSLEESTSSPSEPEDVIDLVQPAPGAGEAEGL--------------PEGTQAAGP---AP 134
P S+SS S + V+P PG A+ P + P AP
Sbjct: 394 PGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAP 453
Query: 135 AGKEHRKQDAETPPPPDPPAPETLLAPPPLPS-----------------------TPDPP 171
A H PP PP P LL PPP P+ T PP
Sbjct: 454 AATPHLSLPPGPSSPPPPPCPR-LLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPP 512
Query: 172 RRELRAPSPPVEH-------PRLLRSV--------PTPLVMAQKISERMAGNEALSPTSP 216
R AP PP+ H P SV PTP S +G+ + SP P
Sbjct: 513 R---PAP-PPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGP 568
Query: 217 FREGRPGEWRTPAARGPRSGDPGPGPSHPAQ--PKAPRFPSNIIVTNGAAREPRRTLSRA 274
P RS DP P P PAQ P P + + + S +
Sbjct: 569 VS-------FPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGS 621
Query: 275 AVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPGG--GSSPERVARGRG-LPGPAESLRA 331
+ R +V +FP + G G P G +P+ V G G LP
Sbjct: 622 FRRPESPRPRV---------SFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPA------- 665
Query: 332 GGQAPRGPALANGFPSAHEALKSAPSSF 359
RGP L + P+ E P+ F
Sbjct: 666 -----RGPRLFDFPPTPLEDQFEEPAEF 688
Score = 30.4 bits (67), Expect = 3.3
Identities = 21/54 (38%), Positives = 24/54 (44%), Gaps = 9/54 (16%)
Query: 136 GKEHRKQD---AETPPPPDPPAPETLLAP-----PPLPSTPDPPRRELRAPSPP 181
G+E + D A PP PAP + AP PP S P RE AP PP
Sbjct: 1030 GREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKARE-EAPGPP 1082
>gi|169217659 PREDICTED: similar to ectonucleotide
pyrophosphatase/phosphodiesterase 5 [Homo sapiens]
Length = 542
Score = 54.7 bits (130), Expect = 2e-07
Identities = 74/283 (26%), Positives = 98/283 (34%), Gaps = 48/283 (16%)
Query: 87 CCLCSPSLEESTSSPSEPED------VIDLVQPAPGAGEAEGLPEGTQAAGPA--PAGKE 138
C LCS S+ P +DL PA A + P + GPA PA ++
Sbjct: 216 CLLCSAERRNCESAYVSPRPDPTIPGTLDLTGPASRAPNPDSAPPKLRILGPAPGPASED 275
Query: 139 HRKQDAETPPPPDPPAPET---------LLAPPPLPSTPDPPRRELRAPSPPVEHPRLLR 189
H + PP PE+ ++ PPLP P L P H R
Sbjct: 276 HGLAPGPSSNPPQLRLPESAHRLAVCYDIVNAPPLPRLLSPSLGLLSCP-----HARHCL 330
Query: 190 SVPTPLVMAQKISERMAGNEALSPTSPFREGRPGEWR------TPAARGPRSG----DPG 239
T + +EA P SP+ PG P PR+ PG
Sbjct: 331 QDAT----------NLNASEAQLPGSPYPGPAPGTANLDSPQDLPQQSAPRTHLLTVSPG 380
Query: 240 PGPSHPAQPKAPRFPSNIIVTNGAAREPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAA 299
P PS P P+ P + G + R+ A V E A + G F AA
Sbjct: 381 PAPSLP--PRTALGPPPLQSRPGFLQVSRQRCGSAHVMAPEENAGTELWLQGFERRFLAA 438
Query: 300 GD--AGEGAPGGGSSPERVARGRGLPGPAESLRAGGQAPRGPA 340
+ GG+S E GRG PG A+ + G + P PA
Sbjct: 439 RSLRSFPWQVAGGASGE-ARGGRGSPG-ADGMGLGAETPGAPA 479
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 54.7 bits (130), Expect = 2e-07
Identities = 88/345 (25%), Positives = 117/345 (33%), Gaps = 75/345 (21%)
Query: 109 DLVQPAPGAGEAEGLPEG-TQAAGPAPAGKEHRKQDAETPPPPDPPAPETLLAPPPLPST 167
DL+ P P G A G P+ ++ G +P +PP PP P LL PPP PS
Sbjct: 136 DLLIPPPPPGPAPGPPQDISEPPGGSPL---------PSPPSTAPPPPPLLLEPPPPPSM 186
Query: 168 PDPPRRELRAPSPPVEHPRLLRSVPT---------PLVMAQKISERMAGNEALSPTSP-- 216
PP L A SPP H S+PT PL + +P SP
Sbjct: 187 APPPPPVLEALSPP--HTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHT 244
Query: 217 -----FREGRPGEWRTPAARGPRSGDP--GPGPSHPAQPK----APRFPSNIIVTNGAAR 265
F G +W++ A R + P PA+PK P ++
Sbjct: 245 VGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKV 304
Query: 266 EPRRTLSRAAVSVQER----RAQVLAT--------------IHGHAGAFP-------AAG 300
P + +++ VQE R + AT I + +P G
Sbjct: 305 PPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPG 364
Query: 301 DAGEGAPGG---GSSPERVARGRGLPGPAESL--RAGGQAPRGPALANGFPSAHEALKSA 355
+ AP G S + G P PA L A P P L P A K+A
Sbjct: 365 ELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAA 424
Query: 356 --PSSF--APAGKSLCFRPGPALPSTRARQSFPGPRQPNGAQDWR 396
P+ F P S +P P PS P + DWR
Sbjct: 425 HPPAGFTKTPKSSSPALKPKPNPPS-------PENTASSAPVDWR 462
Score = 36.2 bits (82), Expect = 0.060
Identities = 45/189 (23%), Positives = 66/189 (34%), Gaps = 35/189 (18%)
Query: 119 EAEGLPEGTQAAGPAPAGKEHRKQDAETPPPPDPPAPETLLAPPPLPSTPDPPRRELRAP 178
+ G + T A P + + + PPP PP P PPLP PP L
Sbjct: 361 DCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPA---PPLP----PPAPPLPPA 413
Query: 179 SPPVEHPRLLRSVPTPLVMAQKISERMAGNEALSPTSP--FREGRPGEWRTPAAR----- 231
+PP+ + P K S A +P SP P +WR P+
Sbjct: 414 APPLPCAQKAAHPPAGFTKTPK-SSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRN 472
Query: 232 -------GPRSGD------PGP--GPSHPAQPKAPRFPSNIIVTNGAARE-----PRRTL 271
G R D PGP P K PR P + + A++ P ++L
Sbjct: 473 ELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSL 532
Query: 272 SRAAVSVQE 280
++++ E
Sbjct: 533 GGSSLTETE 541
Score = 31.2 bits (69), Expect = 1.9
Identities = 70/322 (21%), Positives = 100/322 (31%), Gaps = 41/322 (12%)
Query: 91 SPSLEESTSSPSEPEDVIDLVQPAPGAGEAEGLPEGTQAAGPAPAGKEHRKQDAETPPPP 150
+P +E P PE L PA G+PE + + E P
Sbjct: 497 APQSKEGKKGPRLPEKETLLSLPAKDT--PPGVPEKSLGGSSLT--------ETEAAPSL 546
Query: 151 DPPAPETLLAPPPLPSTPDPPRRELRAPSPPVEHPRLLRSV----PTPLVMAQKISERMA 206
P+ + + P PS R EL A S+ P P + +I E A
Sbjct: 547 TLPSVDYIPQDSPTPSVRQI-RNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGA 605
Query: 207 GNEALSPTSPFREGRPGEWRT-----------------PAARGPRSGDPGPGPSHPAQP- 248
++ LS P + P + T P P P PA P
Sbjct: 606 DDDKLS--KPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPP 663
Query: 249 KAPRFPSNIIVTNGAAREPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPG 308
KA P+ + P + S A++ A L T A +G AG+
Sbjct: 664 KATLGPATPLKATSGPTTPLKATSGPAIA---STATTLPTTTSQLMAEKDSGPAGQPEKP 720
Query: 309 GGSSPERVARGRGLPGPAESLRAGGQAPRGPALANGFPSAHEALKSAPSSFAP-AGKSLC 367
++ RG P+E+ R Q R A P P + P +S
Sbjct: 721 ASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFP--PKTSPGGGEVPCLYKPHCHQSSL 778
Query: 368 FRPGPALPSTRARQSFPGPRQP 389
R + T AR GP +P
Sbjct: 779 SREVAVVMPTLARGGAAGPGEP 800
Score = 30.0 bits (66), Expect = 4.3
Identities = 31/113 (27%), Positives = 39/113 (34%), Gaps = 14/113 (12%)
Query: 150 PDPPAPETLLAPPPLPSTPDPPRRELRAP-SPPVEHPRLLRSVPTPLVMAQKISERMAGN 208
P + L+ PPP P PP+ P P+ P P PL++ MA
Sbjct: 130 PGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPP 189
Query: 209 -----EALSPTSPFRE---GRPGEWRTPA-----ARGPRSGDPGPGPSHPAQP 248
EALSP P ++ PA P P P P PA P
Sbjct: 190 PPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASP 242
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 54.7 bits (130), Expect = 2e-07
Identities = 88/345 (25%), Positives = 117/345 (33%), Gaps = 75/345 (21%)
Query: 109 DLVQPAPGAGEAEGLPEG-TQAAGPAPAGKEHRKQDAETPPPPDPPAPETLLAPPPLPST 167
DL+ P P G A G P+ ++ G +P +PP PP P LL PPP PS
Sbjct: 136 DLLIPPPPPGPAPGPPQDISEPPGGSPL---------PSPPSTAPPPPPLLLEPPPPPSM 186
Query: 168 PDPPRRELRAPSPPVEHPRLLRSVPT---------PLVMAQKISERMAGNEALSPTSP-- 216
PP L A SPP H S+PT PL + +P SP
Sbjct: 187 APPPPPVLEALSPP--HTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHT 244
Query: 217 -----FREGRPGEWRTPAARGPRSGDP--GPGPSHPAQPK----APRFPSNIIVTNGAAR 265
F G +W++ A R + P PA+PK P ++
Sbjct: 245 VGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKV 304
Query: 266 EPRRTLSRAAVSVQER----RAQVLAT--------------IHGHAGAFP-------AAG 300
P + +++ VQE R + AT I + +P G
Sbjct: 305 PPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPG 364
Query: 301 DAGEGAPGG---GSSPERVARGRGLPGPAESL--RAGGQAPRGPALANGFPSAHEALKSA 355
+ AP G S + G P PA L A P P L P A K+A
Sbjct: 365 ELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAA 424
Query: 356 --PSSF--APAGKSLCFRPGPALPSTRARQSFPGPRQPNGAQDWR 396
P+ F P S +P P PS P + DWR
Sbjct: 425 HPPAGFTKTPKSSSPALKPKPNPPS-------PENTASSAPVDWR 462
Score = 36.2 bits (82), Expect = 0.060
Identities = 45/189 (23%), Positives = 66/189 (34%), Gaps = 35/189 (18%)
Query: 119 EAEGLPEGTQAAGPAPAGKEHRKQDAETPPPPDPPAPETLLAPPPLPSTPDPPRRELRAP 178
+ G + T A P + + + PPP PP P PPLP PP L
Sbjct: 361 DCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPA---PPLP----PPAPPLPPA 413
Query: 179 SPPVEHPRLLRSVPTPLVMAQKISERMAGNEALSPTSP--FREGRPGEWRTPAAR----- 231
+PP+ + P K S A +P SP P +WR P+
Sbjct: 414 APPLPCAQKAAHPPAGFTKTPK-SSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRN 472
Query: 232 -------GPRSGD------PGP--GPSHPAQPKAPRFPSNIIVTNGAARE-----PRRTL 271
G R D PGP P K PR P + + A++ P ++L
Sbjct: 473 ELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSL 532
Query: 272 SRAAVSVQE 280
++++ E
Sbjct: 533 GGSSLTETE 541
Score = 31.2 bits (69), Expect = 1.9
Identities = 70/322 (21%), Positives = 100/322 (31%), Gaps = 41/322 (12%)
Query: 91 SPSLEESTSSPSEPEDVIDLVQPAPGAGEAEGLPEGTQAAGPAPAGKEHRKQDAETPPPP 150
+P +E P PE L PA G+PE + + E P
Sbjct: 497 APQSKEGKKGPRLPEKETLLSLPAKDT--PPGVPEKSLGGSSLT--------ETEAAPSL 546
Query: 151 DPPAPETLLAPPPLPSTPDPPRRELRAPSPPVEHPRLLRSV----PTPLVMAQKISERMA 206
P+ + + P PS R EL A S+ P P + +I E A
Sbjct: 547 TLPSVDYIPQDSPTPSVRQI-RNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGA 605
Query: 207 GNEALSPTSPFREGRPGEWRT-----------------PAARGPRSGDPGPGPSHPAQP- 248
++ LS P + P + T P P P PA P
Sbjct: 606 DDDKLS--KPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPP 663
Query: 249 KAPRFPSNIIVTNGAAREPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPG 308
KA P+ + P + S A++ A L T A +G AG+
Sbjct: 664 KATLGPATPLKATSGPTTPLKATSGPAIA---STATTLPTTTSQLMAEKDSGPAGQPEKP 720
Query: 309 GGSSPERVARGRGLPGPAESLRAGGQAPRGPALANGFPSAHEALKSAPSSFAP-AGKSLC 367
++ RG P+E+ R Q R A P P + P +S
Sbjct: 721 ASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFP--PKTSPGGGEVPCLYKPHCHQSSL 778
Query: 368 FRPGPALPSTRARQSFPGPRQP 389
R + T AR GP +P
Sbjct: 779 SREVAVVMPTLARGGAAGPGEP 800
Score = 30.0 bits (66), Expect = 4.3
Identities = 31/113 (27%), Positives = 39/113 (34%), Gaps = 14/113 (12%)
Query: 150 PDPPAPETLLAPPPLPSTPDPPRRELRAP-SPPVEHPRLLRSVPTPLVMAQKISERMAGN 208
P + L+ PPP P PP+ P P+ P P PL++ MA
Sbjct: 130 PGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPP 189
Query: 209 -----EALSPTSPFRE---GRPGEWRTPA-----ARGPRSGDPGPGPSHPAQP 248
EALSP P ++ PA P P P P PA P
Sbjct: 190 PPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASP 242
>gi|169167316 PREDICTED: similar to ectonucleotide
pyrophosphatase/phosphodiesterase 5 [Homo sapiens]
Length = 542
Score = 54.7 bits (130), Expect = 2e-07
Identities = 74/283 (26%), Positives = 98/283 (34%), Gaps = 48/283 (16%)
Query: 87 CCLCSPSLEESTSSPSEPED------VIDLVQPAPGAGEAEGLPEGTQAAGPA--PAGKE 138
C LCS S+ P +DL PA A + P + GPA PA ++
Sbjct: 216 CLLCSAERRNCESAYVSPRPDPTIPGTLDLTGPASRAPNPDSAPPKLRILGPAPGPASED 275
Query: 139 HRKQDAETPPPPDPPAPET---------LLAPPPLPSTPDPPRRELRAPSPPVEHPRLLR 189
H + PP PE+ ++ PPLP P L P H R
Sbjct: 276 HGLAPGPSSNPPQLRLPESAHRLAVCYDIVNAPPLPRLLSPSLGLLSCP-----HARHCL 330
Query: 190 SVPTPLVMAQKISERMAGNEALSPTSPFREGRPGEWR------TPAARGPRSG----DPG 239
T + +EA P SP+ PG P PR+ PG
Sbjct: 331 QDAT----------NLNASEAQLPGSPYPGPAPGTANLDSPQDLPQQSAPRTHLLTVSPG 380
Query: 240 PGPSHPAQPKAPRFPSNIIVTNGAAREPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAA 299
P PS P P+ P + G + R+ A V E A + G F AA
Sbjct: 381 PAPSLP--PRTALGPPPLQSRPGFLQVSRQRCGSAHVMAPEENAGTELWLQGFERRFLAA 438
Query: 300 GD--AGEGAPGGGSSPERVARGRGLPGPAESLRAGGQAPRGPA 340
+ GG+S E GRG PG A+ + G + P PA
Sbjct: 439 RSLRSFPWQVAGGASGE-ARGGRGSPG-ADGMGLGAETPGAPA 479
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
sapiens]
Length = 1188
Score = 54.7 bits (130), Expect = 2e-07
Identities = 88/345 (25%), Positives = 117/345 (33%), Gaps = 75/345 (21%)
Query: 109 DLVQPAPGAGEAEGLPEG-TQAAGPAPAGKEHRKQDAETPPPPDPPAPETLLAPPPLPST 167
DL+ P P G A G P+ ++ G +P +PP PP P LL PPP PS
Sbjct: 136 DLLIPPPPPGPAPGPPQDISEPPGGSPL---------PSPPSTAPPPPPLLLEPPPPPSM 186
Query: 168 PDPPRRELRAPSPPVEHPRLLRSVPT---------PLVMAQKISERMAGNEALSPTSP-- 216
PP L A SPP H S+PT PL + +P SP
Sbjct: 187 APPPPPVLEALSPP--HTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHT 244
Query: 217 -----FREGRPGEWRTPAARGPRSGDP--GPGPSHPAQPK----APRFPSNIIVTNGAAR 265
F G +W++ A R + P PA+PK P ++
Sbjct: 245 VGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKV 304
Query: 266 EPRRTLSRAAVSVQER----RAQVLAT--------------IHGHAGAFP-------AAG 300
P + +++ VQE R + AT I + +P G
Sbjct: 305 PPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPG 364
Query: 301 DAGEGAPGG---GSSPERVARGRGLPGPAESL--RAGGQAPRGPALANGFPSAHEALKSA 355
+ AP G S + G P PA L A P P L P A K+A
Sbjct: 365 ELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAA 424
Query: 356 --PSSF--APAGKSLCFRPGPALPSTRARQSFPGPRQPNGAQDWR 396
P+ F P S +P P PS P + DWR
Sbjct: 425 HPPAGFTKTPKSSSPALKPKPNPPS-------PENTASSAPVDWR 462
Score = 36.2 bits (82), Expect = 0.060
Identities = 45/189 (23%), Positives = 66/189 (34%), Gaps = 35/189 (18%)
Query: 119 EAEGLPEGTQAAGPAPAGKEHRKQDAETPPPPDPPAPETLLAPPPLPSTPDPPRRELRAP 178
+ G + T A P + + + PPP PP P PPLP PP L
Sbjct: 361 DCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPA---PPLP----PPAPPLPPA 413
Query: 179 SPPVEHPRLLRSVPTPLVMAQKISERMAGNEALSPTSP--FREGRPGEWRTPAAR----- 231
+PP+ + P K S A +P SP P +WR P+
Sbjct: 414 APPLPCAQKAAHPPAGFTKTPK-SSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRN 472
Query: 232 -------GPRSGD------PGP--GPSHPAQPKAPRFPSNIIVTNGAARE-----PRRTL 271
G R D PGP P K PR P + + A++ P ++L
Sbjct: 473 ELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSL 532
Query: 272 SRAAVSVQE 280
++++ E
Sbjct: 533 GGSSLTETE 541
Score = 31.2 bits (69), Expect = 1.9
Identities = 70/322 (21%), Positives = 100/322 (31%), Gaps = 41/322 (12%)
Query: 91 SPSLEESTSSPSEPEDVIDLVQPAPGAGEAEGLPEGTQAAGPAPAGKEHRKQDAETPPPP 150
+P +E P PE L PA G+PE + + E P
Sbjct: 497 APQSKEGKKGPRLPEKETLLSLPAKDT--PPGVPEKSLGGSSLT--------ETEAAPSL 546
Query: 151 DPPAPETLLAPPPLPSTPDPPRRELRAPSPPVEHPRLLRSV----PTPLVMAQKISERMA 206
P+ + + P PS R EL A S+ P P + +I E A
Sbjct: 547 TLPSVDYIPQDSPTPSVRQI-RNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRICENGA 605
Query: 207 GNEALSPTSPFREGRPGEWRT-----------------PAARGPRSGDPGPGPSHPAQP- 248
++ LS P + P + T P P P PA P
Sbjct: 606 DDDKLS--KPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPATPP 663
Query: 249 KAPRFPSNIIVTNGAAREPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPG 308
KA P+ + P + S A++ A L T A +G AG+
Sbjct: 664 KATLGPATPLKATSGPTTPLKATSGPAIA---STATTLPTTTSQLMAEKDSGPAGQPEKP 720
Query: 309 GGSSPERVARGRGLPGPAESLRAGGQAPRGPALANGFPSAHEALKSAPSSFAP-AGKSLC 367
++ RG P+E+ R Q R A P P + P +S
Sbjct: 721 ASQEVSTPSQARGEGSPSEATRLPTQGARSSAAFP--PKTSPGGGEVPCLYKPHCHQSSL 778
Query: 368 FRPGPALPSTRARQSFPGPRQP 389
R + T AR GP +P
Sbjct: 779 SREVAVVMPTLARGGAAGPGEP 800
Score = 30.0 bits (66), Expect = 4.3
Identities = 31/113 (27%), Positives = 39/113 (34%), Gaps = 14/113 (12%)
Query: 150 PDPPAPETLLAPPPLPSTPDPPRRELRAP-SPPVEHPRLLRSVPTPLVMAQKISERMAGN 208
P + L+ PPP P PP+ P P+ P P PL++ MA
Sbjct: 130 PGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPPPSMAPP 189
Query: 209 -----EALSPTSPFRE---GRPGEWRTPA-----ARGPRSGDPGPGPSHPAQP 248
EALSP P ++ PA P P P P PA P
Sbjct: 190 PPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASP 242
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.131 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,969,134
Number of Sequences: 37866
Number of extensions: 1874463
Number of successful extensions: 28618
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 601
Number of HSP's successfully gapped in prelim test: 1958
Number of HSP's that attempted gapping in prelim test: 11728
Number of HSP's gapped (non-prelim): 9750
length of query: 435
length of database: 18,247,518
effective HSP length: 105
effective length of query: 330
effective length of database: 14,271,588
effective search space: 4709624040
effective search space used: 4709624040
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.