Search of human proteins with 21687188

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21687188 hypothetical protein LOC146325 [Homo sapiens]
         (571 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21687188 hypothetical protein LOC146325 [Homo sapiens]            1203   0.0  
gi|113204609 zinc finger protein 750 [Homo sapiens]                   104   2e-22
gi|163965366 nascent polypeptide-associated complex alpha subuni...    75   1e-13
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    74   3e-13
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    69   1e-11
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       67   4e-11
gi|154759255 collagen, type XXVIII precursor [Homo sapiens]            66   1e-10
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      65   2e-10
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    65   2e-10
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    65   2e-10
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    65   2e-10
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          62   1e-09
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    62   1e-09
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    62   2e-09
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...    61   2e-09
gi|119829187 alpha 1 type XVII collagen [Homo sapiens]                 61   2e-09
gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]                    61   2e-09
gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]           60   4e-09
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              60   4e-09
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       60   5e-09
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    60   7e-09
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...    59   9e-09
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...    59   9e-09
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     59   9e-09
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      59   1e-08
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo...    59   1e-08
gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo s...    59   2e-08
gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo s...    59   2e-08
gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo s...    59   2e-08
gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo s...    59   2e-08

>gi|21687188 hypothetical protein LOC146325 [Homo sapiens]
          Length = 571

 Score = 1203 bits (3113), Expect = 0.0
 Identities = 571/571 (100%), Positives = 571/571 (100%)

Query: 1   MSREAGSCRVGTGARARSRKPKKPHYIPRPWGKPYNYKCFQCPFTCLEKSHLYNHMKYSL 60
           MSREAGSCRVGTGARARSRKPKKPHYIPRPWGKPYNYKCFQCPFTCLEKSHLYNHMKYSL
Sbjct: 1   MSREAGSCRVGTGARARSRKPKKPHYIPRPWGKPYNYKCFQCPFTCLEKSHLYNHMKYSL 60

Query: 61  CKDSLSLLLDSPDWACRRGSTTPRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVAD 120
           CKDSLSLLLDSPDWACRRGSTTPRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVAD
Sbjct: 61  CKDSLSLLLDSPDWACRRGSTTPRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVAD 120

Query: 121 IHSLHCGGGPKSRAKGSPGPPPPVARATRKGPGPSGLLPESWKPGMGGDPRGVGAGDMAS 180
           IHSLHCGGGPKSRAKGSPGPPPPVARATRKGPGPSGLLPESWKPGMGGDPRGVGAGDMAS
Sbjct: 121 IHSLHCGGGPKSRAKGSPGPPPPVARATRKGPGPSGLLPESWKPGMGGDPRGVGAGDMAS 180

Query: 181 AGPEGSVPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASAS 240
           AGPEGSVPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASAS
Sbjct: 181 AGPEGSVPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASAS 240

Query: 241 PLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPG 300
           PLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPG
Sbjct: 241 PLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPG 300

Query: 301 LLKVPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRS 360
           LLKVPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRS
Sbjct: 301 LLKVPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRS 360

Query: 361 SLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQ 420
           SLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQ
Sbjct: 361 SLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQ 420

Query: 421 RLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQAL 480
           RLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQAL
Sbjct: 421 RLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQAL 480

Query: 481 GEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLPLAAPDDPVI 540
           GEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLPLAAPDDPVI
Sbjct: 481 GEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLPLAAPDDPVI 540

Query: 541 PGSGWGTCVATRSSQTPEAVCGLQSPQGAEV 571
           PGSGWGTCVATRSSQTPEAVCGLQSPQGAEV
Sbjct: 541 PGSGWGTCVATRSSQTPEAVCGLQSPQGAEV 571


>gi|113204609 zinc finger protein 750 [Homo sapiens]
          Length = 723

 Score =  104 bits (259), Expect = 2e-22
 Identities = 99/316 (31%), Positives = 136/316 (43%), Gaps = 45/316 (14%)

Query: 17  RSRKPKKPHYIPRPWGKPYNYKCFQCPFTCLEKSHLYNHMKYSLCKDSLSLLLDSPDWAC 76
           + RKPKKPHYIPRP GKP+ YKCFQCPFTC EKSHL+NHMKY LCK+S++L+ +      
Sbjct: 5   KERKPKKPHYIPRPPGKPFKYKCFQCPFTCNEKSHLFNHMKYGLCKNSITLVSEQD---- 60

Query: 77  RRGSTTPRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGG------GP 130
            R    P+ ++  P +  + D   +P  ++    + A  L   D    H           
Sbjct: 61  -RVPKCPKSNSLDPKQTNQPDATAKPASSK----SVANGLSAFDSKLQHSSAREDIKENL 115

Query: 131 KSRAKGSP---GPPPPVARATR-KGPGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGS 186
           + +A+G+    G  P + RA+  K P P   L        G  P   GA   ++  P G 
Sbjct: 116 ELQARGTHRCLGQKPALHRASPCKSPAPEAAL--------GAQPALEGAARPSAFVPVGE 167

Query: 187 VPCYPPPAPGEFPEAHSLH-LSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASP-LLP 244
                 P   E PE  +LH  +   V++       +   P     A  PFL    P  + 
Sbjct: 168 -HRLKGPDNAEAPETLALHNPTAKAVSFHTKSAFHT---PGYPWKAGSPFLPPEFPHKIS 223

Query: 245 PATAFPAVQPPQRPTPAPRLYYPLLLEHTLG------LPAGKAALAKAPVSPRSPSGTPA 298
                 A+ P   PT  P        EH L       L AG +    AP+   S  GT  
Sbjct: 224 STKGLGAISPYMHPT-IPEYPPHFYTEHGLATIYSPYLLAGSSPECDAPL--LSVYGTQD 280

Query: 299 PGLLKVPVPGLGPWPR 314
           P   +  +P  GP P+
Sbjct: 281 P---RHFLPHPGPIPK 293


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 75.5 bits (184), Expect = 1e-13
 Identities = 131/486 (26%), Positives = 168/486 (34%), Gaps = 82/486 (16%)

Query: 83   PRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRAKGSPGPPP 142
            P P A TP  P        P+GA P   A  P      + +    G P + A   P P  
Sbjct: 1080 PTPPAATPPSPKGGPATPSPKGA-PMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG 1138

Query: 143  PVARATRKG-PGPSGLLPESWKPGMGGDP-RGVGA----------GDMASAGPEGS--VP 188
             +A    KG P      P S K G+   P +G             G +A+  P+G+   P
Sbjct: 1139 GLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1198

Query: 189  CYPPPAP-GEFPEAHSLHLSLLGVNYPLSP--GLFSYLGPSLAAAAHVPFLASASPLLPP 245
               PP+P G                 P SP  GL +   PS   A   P     SP   P
Sbjct: 1199 AATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT---PSPKGAPTTPAATPPSPKGGP 1255

Query: 246  ATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPA---PGLL 302
            AT      PP +  P P    P  L+  L  P  K A   A V+P SP G PA   P   
Sbjct: 1256 AT------PPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGA 1309

Query: 303  KVPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFC-SRSS 361
              P     P P+ +P  P  +G     A + P            PK +P+L     S   
Sbjct: 1310 PTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPS-----------PKGTPTLPATTPSSKG 1358

Query: 362  LPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGP--VPGSPEHVGEDLTRALGDYARVE 419
             PT            P   E P P    P    GP   P SP+  G  +    GD     
Sbjct: 1359 GPT-----------TPSSKEGPTPPAATPSHKGGPAMTPPSPKR-GPAIPSPKGD--PTS 1404

Query: 420  QRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPA----K 475
              +  L P    A    RE         LT           P A   +S+K+APA    K
Sbjct: 1405 PAVIPLSPKKAPATPVTREGAATPSKGDLT-----------PPAVTPVSLKKAPATSAPK 1453

Query: 476  GPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPP---PGLPL 532
            G  A   + G P L P +T     PP    P AP+  +  ++  +A ++  P   P LP 
Sbjct: 1454 GGPATPSSKGDPTL-PAVT-----PPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPA 1507

Query: 533  AAPDDP 538
              P  P
Sbjct: 1508 VIPSSP 1513



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 131/540 (24%), Positives = 181/540 (33%), Gaps = 64/540 (11%)

Query: 81   TTPRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRAKGSPGP 140
            TTP    P+P + G + P   P+GA PT  A  P      + +    G P + A   P P
Sbjct: 1150 TTPAATPPSP-KGGLATP--PPKGA-PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSP 1205

Query: 141  PPPVARATRKG-PGPSGLLPESWKPGMGG-DPRGVGAGDMASAGPEGSVPCYPPPAPGEF 198
               +A  + KG P      P S K G+    P+G      A+       P  PPP     
Sbjct: 1206 KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPT 1265

Query: 199  PEAHSLHLSLLGVNYPL-----SPGLFSYLGPSLAAAAHVPFLASASPLL-PPATAFPAV 252
            P A +      G+  P      +P + +   P    A   P  A   P   PP+      
Sbjct: 1266 PPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPG 1325

Query: 253  QPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPGL---------LK 303
             PP +  P P    P   + T  LPA   +    P +P S  G   P           + 
Sbjct: 1326 TPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMT 1385

Query: 304  VPVPGLGPW---PRVTPRDPGQEGELERAAQSDP--RRRLSLGSRLEL--PKASPSLTRF 356
             P P  GP    P+  P  P       + A + P  R   +  S+ +L  P  +P   + 
Sbjct: 1386 PPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKK 1445

Query: 357  CSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGP-----------VPGSPEHVG 405
               +S P G            G P  P    P P +P  P            P +P  +G
Sbjct: 1446 APATSAPKGGPAT----PSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMG 1501

Query: 406  EDLTRALGDYARVE------QRLGQLGPAGGL----APRPLREQLGKIRLELLTIHQALE 455
                 A+   +  E       R   + P   L     P  L  +   I   +        
Sbjct: 1502 APTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKT 1561

Query: 456  QAV-RPPDAPLDLSVKRA---PAKGPQALGEAWGRPEL--GPVLTGGTP-EPPGMLGPAA 508
             A+  P +AP   S K A   PA  P     A    EL   P +T  +P E P       
Sbjct: 1562 PAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTP 1621

Query: 509  PQPFSGHTTKCEADSSVPPPGLPLAAPDDPVIPGSGWGTCVATRSSQTPEAVCGLQSPQG 568
            P P  G  T     +   PP  P +  D P  P S   TC     +  P+A  GL + +G
Sbjct: 1622 PSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPAS--VTC--KMGATVPQASKGLPAKKG 1677



 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 131/536 (24%), Positives = 170/536 (31%), Gaps = 87/536 (16%)

Query: 78   RGSTTPRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRA-KG 136
            +G+ TP    P   + G + P  +     P    P+P             GGP + + KG
Sbjct: 937  KGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPK------------GGPATPSPKG 984

Query: 137  SPGPP---PPVARATRKGPGPSGLL--PESWKPGMGGDPRGVGAGDMASAGPEGSVPCYP 191
            +P PP   PP  +     P P G    P    P   G P        AS  P  +     
Sbjct: 985  APTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAAT----- 1039

Query: 192  PPAPGEFPEAHSLHLSLLGVNYPLSPG--LFSYLG----PSLAAAAHVPFLASASPLLPP 245
            PP+P   P A  L         P +P   L S  G    PSL  A   P     SP   P
Sbjct: 1040 PPSPKGSPAATPLPKGA-----PTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGP 1094

Query: 246  ATAFP--AVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPV----------SPRSP 293
            AT  P  A  PP    P+P+    L      G P   AA   +P           +P +P
Sbjct: 1095 ATPSPKGAPMPPAATPPSPK--GGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTP 1152

Query: 294  SGTPAP---GLLKVPVPGLGPWPRVTPRDP-------GQEGELERAAQSDPRRRLSLGSR 343
            + TP     GL   P  G    P  TP  P         +G     A + P  +  L + 
Sbjct: 1153 AATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT- 1211

Query: 344  LELPKASPSLTRFCSRS-----SLPTGSSVMLWPEDGDP---GGPETPGPEGPLPLQPRG 395
               PK +P+       S     + P+       P    P   GGP TP P+G  P  P  
Sbjct: 1212 -PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGA-PTPPAA 1269

Query: 396  PVPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALE 455
              P     +     +   + A V        P GG A  P +   G       T      
Sbjct: 1270 TPPSLKGGLATPPHKGAPNPAVVTPP----SPKGGPATSPPK---GAPTPPAATPPSPKG 1322

Query: 456  QAVRPPD--APLDLSVKRAPAKGPQAL---------GEAWGRPELGPVLTGGTPEPPGML 504
                PP   AP   +V     KG   L         G      + GP     TP   G  
Sbjct: 1323 SPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGP 1382

Query: 505  GPAAPQPFSGHTTKCEADSSVPPPGLPLAAPDDPVIPGSGWGTCVATRSSQTPEAV 560
                P P  G            P  +PL+    P  P +  G    ++   TP AV
Sbjct: 1383 AMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAV 1438



 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 117/510 (22%), Positives = 167/510 (32%), Gaps = 95/510 (18%)

Query: 83   PRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRA----KGSP 138
            P P A TP   G   P   P   +   A P+P             G P S A        
Sbjct: 1369 PTPPAATPSHKG--GPAMTPPSPKRGPAIPSPK------------GDPTSPAVIPLSPKK 1414

Query: 139  GPPPPVARATRKGPGPSGLLPESWKP------GMGGDPRGVGAGDMASAGPEGSVPCYPP 192
             P  PV R     P    L P +  P           P+G  A   +   P  ++P   P
Sbjct: 1415 APATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDP--TLPAVTP 1472

Query: 193  PAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAA-----HVPFLASA--SPLLP- 244
            P+P E P    +  S      P +P       P+L A        VP   S+   P+ P 
Sbjct: 1473 PSPKEPPAPKQVATSSSPKKAPATPAPMG--APTLPAVIPSSPKEVPATPSSRRDPIAPT 1530

Query: 245  --------PATAFP--AVQPPQRPTPAPRLYYPLLL-EHTLGLPAGKAALAKAPVSPRSP 293
                    PAT  P  A+ PP    P+P+    +   +     P+ K A +   V+P + 
Sbjct: 1531 ATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTY 1590

Query: 294  SGTPAPGLLKVPVPGLGPWPRVTPRDPG------QEGELERAAQSDPRRRLSLGSRLELP 347
             G P+P  L +P     P P+  P  P       ++G    A +  P       S L+  
Sbjct: 1591 KGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDS 1650

Query: 348  KASPSLTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEG-----PLPLQPRGPVPGSPE 402
              SP+       +++P  S           G P   GP         P     P+  +P 
Sbjct: 1651 PTSPASVTCKMGATVPQASK----------GLPAKKGPTALKEVLVAPAPESTPIITAPT 1700

Query: 403  HVGEDLTRALGDYARV----EQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAV 458
              G    ++      +      + G  GP   +AP P           LL + +   +  
Sbjct: 1701 RKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAP-----------LLPVQKDSSKTA 1749

Query: 459  RPPDAPLDLSVKRAPAKG-------PQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQP 511
            +  DA        AP +          A  +   +PE   V     P PP  L P AP P
Sbjct: 1750 KGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASV--SAAPSPPVSL-PLAPSP 1806

Query: 512  FSGHTTKCEADSSVPPPGLPLAAPDDPVIP 541
                  K +   S   PGL L +P  P+ P
Sbjct: 1807 VPTLPPKQQFLPS--SPGLVLESPSKPLAP 1834



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 138/550 (25%), Positives = 176/550 (32%), Gaps = 123/550 (22%)

Query: 62   KDSLSLLLDSPDWACRRGSTTPRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADI 121
            K +L+ L DSP  +    S +P+   P P + G + P   P G   +  +P     + + 
Sbjct: 784  KGTLTYLADSP--SPLGVSVSPQTKRP-PTKKGSAGPDT-PIGNLSSPVSPVEASFLPE- 838

Query: 122  HSLHCGGGPKSRAKG-SPGPPPPVARATRKGPGPSGLLPESWKPGMGGDPRGVGAGDMAS 180
            +SL   G   S A   SP PP P     +  P PS + P S        P+GV       
Sbjct: 839  NSLSFQGSKDSPATTHSPTPPSP-----KGAPTPSAVTPLS--------PKGV------- 878

Query: 181  AGPEGSVPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASAS 240
                 ++P    P P               VN P     F   GP+  A    P L+  S
Sbjct: 879  -----TLPPKETPTPSV-------------VNLP-----FPKEGPATPAPKQAPALSMTS 915

Query: 241  PLLPPATAFPA-----VQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSG 295
                 A A PA       P  +  P P    P   +     P+ K A      +P SP G
Sbjct: 916  SSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKG 975

Query: 296  ---TPAPGLLKVPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPS 352
               TP+P     P     P P+  P  P  +G     A + P            PK SP+
Sbjct: 976  GPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPS-----------PKGSPA 1024

Query: 353  LTRFCSRSSL--------PTGSSVMLWPEDGDP-----------GGPETPG------PEG 387
             T F   +S         P GS        G P           GGP TP       P  
Sbjct: 1025 ATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPA 1084

Query: 388  PLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLEL 447
              P  P+G  P +P   G  +  A    +          P GGLA  P +   G      
Sbjct: 1085 ATPPSPKGG-PATPSPKGAPMPPAATPPS----------PKGGLATPPHK---GAPTTPA 1130

Query: 448  LTIHQALEQAVRPP--DAPLDLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEPPGMLG 505
             T          PP   AP   +      KG    G A   P+  P     TP  P   G
Sbjct: 1131 ATPPSPKGGLATPPPKGAPTTPAATPPSPKG----GLATPPPKGAPTTPAATPPSP-KGG 1185

Query: 506  PAAPQPFSGHTTKCEADSS-------VPPPGLPLAAPDDPVIPGSGWGTCVATRSSQTPE 558
             A P P    TT      S         P G P      P  P  G  T     +  TP 
Sbjct: 1186 LATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1245

Query: 559  AVCGLQSPQG 568
            A     SP+G
Sbjct: 1246 AT--PPSPKG 1253



 Score = 37.7 bits (86), Expect = 0.029
 Identities = 80/391 (20%), Positives = 115/391 (29%), Gaps = 64/391 (16%)

Query: 213  YPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAF-PAVQPPQRPTPAPRLYYPLLLE 271
            +PL     + + P+ A      +  +ASP L    +  P   P +  T       P   E
Sbjct: 648  FPLESADPAGVAPTTAKGTST-YTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASE 706

Query: 272  HTLGLPAGK---AALAKAPVSPRSPSGTPAPGLLKVPVPGLGPWPRVTPRDPGQEGELER 328
            +    P+ +   A LA   ++P  P   P+P L     P  G  P     D         
Sbjct: 707  NCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSL-----PPAGTPPGTKKVDGISHTSALA 761

Query: 329  AAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVMLW----PEDGDPGGPETP- 383
               S P+   +  S      +S     + + S  P G SV       P      GP+TP 
Sbjct: 762  PVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPI 821

Query: 384  ----GPEGPL------------------PLQPRGPVPGSPEHVGEDLTRALGDYARVEQR 421
                 P  P+                  P     P P SP+             A     
Sbjct: 822  GNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKG------------APTPSA 869

Query: 422  LGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQALG 481
            +  L P G   P         + L              P + P   + K+APA    +  
Sbjct: 870  VTPLSPKGVTLPPKETPTPSVVNLPF------------PKEGPATPAPKQAPALSMTSSS 917

Query: 482  EAWGRPELGPVLTGGTPEPPGMLGPAA---PQPFSGHTTKCEADSSVPPPGLPLAAPDDP 538
                R    P     +P P G   P A   P P  G  T     +  PP   P +    P
Sbjct: 918  PKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGP 977

Query: 539  VIPGSGWGTCVATRSSQTPEAVCGLQSPQGA 569
              P           +  +P+      SP+GA
Sbjct: 978  ATPSPKGAPTPPAATPPSPKGGPATPSPKGA 1008



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 78/314 (24%), Positives = 111/314 (35%), Gaps = 58/314 (18%)

Query: 178 MASAGPEGSVPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAA--HVPF 235
           +   GP    PC   PAP + P         L      SP    +  PS  A+    VPF
Sbjct: 38  LGQPGPTLPPPC--SPAPQQCP---------LSAANQASP----FPSPSTIASTPLEVPF 82

Query: 236 LASASPLLPPATAFPAVQPPQRPTPAPRLY------------YPLLLEHTLGLPAGKAAL 283
             S+S      TA P    P+ PT  P L              P++     G P+  A L
Sbjct: 83  PQSSS-----GTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPL 137

Query: 284 AKAPVSPRSPSGTPA--PGLLKVPVPGLGPWPRVTPRDPGQEGELER-AAQSDPRRRLSL 340
           A   ++P S   + A  P LL  P       P V   + G    L    A S+P+  L+ 
Sbjct: 138 ALVALAPHSVQKSSAFPPNLLTSP-------PSVAVAESGSVITLSAPIAPSEPKTNLNK 190

Query: 341 GSRLELPKASPSLTRFCSRSSLPTGS-SVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPG 399
                +P    + +  C  S++P    + M   + G    P+T  P   L +        
Sbjct: 191 VPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTT-PTTTLAI-------A 242

Query: 400 SPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVR 459
           SP+     ++  L       Q  G L   G ++P P    L    L ++T  Q       
Sbjct: 243 SPQVKDTTISSVLIS----PQNPGSLSLKGPVSP-PAALSLSTQSLPVVTSSQKTAGPNT 297

Query: 460 PPDAPLDLSVKRAP 473
           PPD P+ L    AP
Sbjct: 298 PPDFPISLGSHLAP 311



 Score = 33.1 bits (74), Expect = 0.71
 Identities = 93/394 (23%), Positives = 133/394 (33%), Gaps = 69/394 (17%)

Query: 209 LGVNYPLSPGLFSYLGPSLAAAAHVPFLAS-------ASPLL---------PPATAFPA- 251
           +  ++ LSP     L  S  A  H P +A         +PL+          P T F   
Sbjct: 401 VATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVA 460

Query: 252 --VQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPGLLKVPVPGL 309
             V PP    P   +            P   AAL  APV+P+ PS T     L++PV   
Sbjct: 461 TCVSPPMSSGPISNIE-----------PTSPAALVMAPVAPKEPS-TQVATTLRIPVSPP 508

Query: 310 GPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVM 369
            P P      P     ++   Q D +   ++ + LE    SP+     ++        V 
Sbjct: 509 LPDPEDLKNLPSSV-LVKFPTQKDLQ---TVPASLEGAPFSPAQAGLTTKKDPTVLPLVQ 564

Query: 370 LWPEDGDPGGPETPGPEGPLPLQPRGPVP----GSPEHVGE---DLTRALG--DYARVEQ 420
             P++       +  PE  +PL P   +     G P  +G+    +T  LG    A V +
Sbjct: 565 AAPKNSPSFQSTSSSPE--IPLSPEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIK 622

Query: 421 RLGQLGP--AGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAP------------LD 466
                GP  AG L    L+  L    +    +  A    V P  A             L+
Sbjct: 623 TDSYAGPDSAGPL----LKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLE 678

Query: 467 LSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVP 526
            +V  AP   P   G     P L P  +   P  P      A  P +      E   SVP
Sbjct: 679 GTVSLAPKNHPVKEGTLTTLP-LVPTASENCPVAPSPQNTCA--PLATLVLAPEIPKSVP 735

Query: 527 PPGLPLAA--PDDPVIPGSGWGTCVATRSSQTPE 558
            P LP A   P    + G    + +A  +S   E
Sbjct: 736 SPSLPPAGTPPGTKKVDGISHTSALAPVASSPKE 769


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 74.3 bits (181), Expect = 3e-13
 Identities = 128/494 (25%), Positives = 169/494 (34%), Gaps = 72/494 (14%)

Query: 84  RPHAPTPDRPGESDPGRQ--PQGARPTGAA--PAPDLVVADIHSLHCGG----GPKSRAK 135
           RP    P RPG   P R   P G  P  A   P P+        +        GP+    
Sbjct: 96  RPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPA 155

Query: 136 GSPGPPPPVARATRKGPGPS-GLLPESWKPGMG-GDPRGVGAGDMASAGPEGSVPCYPPP 193
           G   P  P A A R GPGP  G  P    PG G G P G GA    + G    +  +   
Sbjct: 156 GPAKPAGPAALAARAGPGPGPGPGPG---PGPGPGKPAGPGAAQTLN-GSAALLNSHHAA 211

Query: 194 APGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAFPAVQ 253
           AP      ++   +LL +  P +PG      P + AAA  P  A+ SP   PA A PA  
Sbjct: 212 APA-VSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAP-PAPAAPSPPAAPAPAAPAAA 269

Query: 254 PPQ-RPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPGLLKVPVPGLGPW 312
           PP   P PA        L    G PAG    A A   P +     + G    P P  G  
Sbjct: 270 PPPPPPAPA-------TLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGP 322

Query: 313 PRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPK-----ASPSLTRFCSRSSLPTGSS 367
             V+    GQ G    AA   P      G + E PK     A P+     +     T +S
Sbjct: 323 AGVS----GQPGPGAAAAAPAP------GVKAESPKRVVQAAPPAAQTLAASGPASTAAS 372

Query: 368 VMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQLGP 427
           +++        GP   G   P P     P PG+P  + +    A+             G 
Sbjct: 373 MVI--------GPTMQGAL-PSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGI 423

Query: 428 AGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRP 487
              L P  L  +L                  +PP  P ++   + P       G    R 
Sbjct: 424 RATLTPTVLAPRL-----------------PQPPQNPTNIQNFQLPP------GMVLVRS 460

Query: 488 ELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGL-PLAAPDDPVIPGSGWG 546
           E G +L         M   A  QP +    +    +S PP  +  + AP  P+I      
Sbjct: 461 ENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQVTP 520

Query: 547 TCVATRSSQTPEAV 560
           T +  + SQ    V
Sbjct: 521 TTIIKQVSQAQTTV 534



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 53/213 (24%), Positives = 68/213 (31%), Gaps = 12/213 (5%)

Query: 81  TTPRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRAKGSPGP 140
           T P   A  P  P    P   P  A P  A P P    A +      G P      +P  
Sbjct: 240 TPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATL--ARPPGHPAGPPTAAPAV 297

Query: 141 PPPVARATRKGPGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCYPPPAPGEFPE 200
           PPP   A  +  G +G  P    P  GG P GV       A      P     +P    +
Sbjct: 298 PPP---AAAQNGGSAGAAPAP-APAAGG-PAGVSGQPGPGAAAAAPAPGVKAESPKRVVQ 352

Query: 201 AHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAFPAVQPPQRPTP 260
           A       L  + P S      +GP++  A     L S + + PPA   P   P      
Sbjct: 353 AAPPAAQTLAASGPASTAASMVIGPTMQGA-----LPSPAAVPPPAPGTPTGLPKGAAGA 407

Query: 261 APRLYYPLLLEHTLGLPAGKAALAKAPVSPRSP 293
             +         T G+ A       AP  P+ P
Sbjct: 408 VTQSLSRTPTATTSGIRATLTPTVLAPRLPQPP 440


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 68.9 bits (167), Expect = 1e-11
 Identities = 131/522 (25%), Positives = 174/522 (33%), Gaps = 81/522 (15%)

Query: 77  RRGSTTPRPHAPTP-----DRPGESDPG--RQPQGARPTGAAPAPDLVVADIHSLHCGGG 129
           RR ++ P P  P+P      R   ++ G  R    ARP      P   V+   S H    
Sbjct: 161 RRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSA-SEHSTTE 219

Query: 130 PKSRAKGSP----GPPPPVARATRKGPGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEG 185
           P   A+  P    G   P +R+      P    P    P   G PR       +   P+G
Sbjct: 220 PSPAARRRPSAGGGLQRPASRSLSSSATPLSS-PARSGPSARGTPRA--PAHPSQPKPKG 276

Query: 186 SVPCYPP----PAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFL----A 237
                PP    P     P    L  S L    P S  L S   P+L A  H   L    A
Sbjct: 277 LQALRPPQVTPPRKDAAPALGPLSSSPLATPSP-SAALQSQAPPTLPATPHSSSLTCQLA 335

Query: 238 SASPLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTP 297
           +  PL PP+   P+  P  +  P+P    P     +LG P  +A  +  P  P SP  TP
Sbjct: 336 TPLPLAPPS---PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP 392

Query: 298 APGLLKVPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRL-----ELPKASPS 352
            P   + P P L   P   P  P     L   A   P+   +L   L       P + P 
Sbjct: 393 PP---QAP-PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV 448

Query: 353 LTRFCSRSSLPTGSS-----------------VMLWPEDGDPGGPE-TPGPEGP-----L 389
              F   +S P   S                 V   P    P  P  TP P+ P      
Sbjct: 449 QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 508

Query: 390 PLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLT 449
           PLQ   P P +P  +     +AL              P+  L   PL     +    L  
Sbjct: 509 PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 568

Query: 450 IHQALEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEPPG------M 503
               L+    PP +P   + +R P  GP     +   P L   L  G P PP       +
Sbjct: 569 --PLLQVPPSPPASPTLQAPRRPPTPGPDT---SVSGPRLTLALAPGPPPPPSRSPSSTL 623

Query: 504 LGP----------AAPQPFSGHTTKCEADSSV-PPPGLPLAA 534
            GP          + P+   G+ +  E  ++  PPP   LAA
Sbjct: 624 SGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA 665



 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 124/459 (27%), Positives = 159/459 (34%), Gaps = 72/459 (15%)

Query: 133 RAKGSPGPPPPVARATRKGPGPSGLLPESWKP------GMGG---DPRGVGAGDMASAGP 183
           R  GSP PPPPV  A  +  G +G +    KP      G+GG         AG   SAG 
Sbjct: 28  RPPGSPRPPPPVTPAALRVLGAAGAVGR--KPLAERAGGIGGATIPESAPRAGPTRSAGT 85

Query: 184 EGSVPCYPPPAPGEFPEAHSLHLSLLG-VNYPLSPGLFSYLGP----SLAAAAHVPFLAS 238
               P   PPA G    A     +  G V+ P      +  GP     L  +A       
Sbjct: 86  SSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARG 145

Query: 239 ASPLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPA 298
            +   P  +A  A        P P    P +   +      +AA  +  +   +PS  P 
Sbjct: 146 KATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS------RAAGTEVGLPRPAPSARPR 199

Query: 299 PGLLKVPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCS 358
           P       P  GP   V+        E   AA    RRR S G  L+ P AS SL+   +
Sbjct: 200 P-------PTEGPRKSVSSASEHSTTEPSPAA----RRRPSAGGGLQRP-ASRSLSSSAT 247

Query: 359 RSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARV 418
             S P  S          P  P  P P+G   L+P    P       +D   ALG  +  
Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR-----KDAAPALGPLS-- 300

Query: 419 EQRLGQLGPAGGLAPR-----PLREQLGKIRLELLTIHQALEQAVRPPDAPLDL-SVKRA 472
              L    P+  L  +     P       +  +L T    L  A   P AP  L ++   
Sbjct: 301 SSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLAT---PLPLAPPSPSAPPSLQTLPSP 357

Query: 473 PAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGL-- 530
           PA  P     + G P L        P PP  L P A  P               PP L  
Sbjct: 358 PATPPSQATTSLGSPTL-QATHSFLPSPP--LSPLATPP------------PQAPPALAL 402

Query: 531 -PLAAPDDPVIPGSGWGTCVATRSSQTPEAVCG--LQSP 566
            PL AP  P  P S   + +AT S Q P A+    LQ+P
Sbjct: 403 PPLQAPPSP--PASPPLSPLATPSPQAPNALAVHLLQAP 439



 Score = 38.1 bits (87), Expect = 0.022
 Identities = 48/151 (31%), Positives = 57/151 (37%), Gaps = 26/151 (17%)

Query: 64  SLSLLLDSPDWACRRGSTTPRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADIHS 123
           S S  L  PD A    S T      TP+     D G  P+G     A+P PD  +A  H 
Sbjct: 618 SPSSTLSGPDLAGHSSSATS-----TPEELRGYDSG--PEGG--AAASPPPDAELAACHP 668

Query: 124 LHCGGGPKSRA--KGSPGPPPPVARATRKGPGPSGLL--------PESWKPGMG----GD 169
                GP      +G+PG P P   AT  GPG +  L        PES  P  G    G 
Sbjct: 669 AAWSRGPAPPLAFRGAPGAPLPWPPAT--GPGSADGLCTIYETEGPESATPAPGALDPGP 726

Query: 170 PRGVGAGDMASAGPEGSVPCYPPPAP-GEFP 199
             G   G  A+    G+    P  A  GE P
Sbjct: 727 SPGTSGGKAAAGAGAGASSRSPKQARLGELP 757


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 129/483 (26%), Positives = 161/483 (33%), Gaps = 122/483 (25%)

Query: 93   PGESDPGRQPQGARPTG-----AAPAPDLVVADIHSLHCGGGPKSRAKGSPGPPPPVARA 147
            PGE  P   PQG  PTG       P P     D    H G   ++  +G  GPP P    
Sbjct: 945  PGERGPNG-PQG--PTGFPGPKGPPGPP--GKDGLPGHPGQRGETGFQGKTGPPGPPGVV 999

Query: 148  TRKGP-GPSGLLPESWKPGMGGDPRGVGA-------GDMASAGPEGSVPCYPPPAPGEFP 199
              +GP G +G + E   PG  G P   G        G     GP G      PP    FP
Sbjct: 1000 GPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFP 1059

Query: 200  EAHSLH-----LSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAFPAVQP 254
                L      L L G   P  P      GP+ +     P   +A P+       P    
Sbjct: 1060 GDRGLPGPVGALGLKGNEGPPGPP-----GPAGSPGERGP-AGAAGPI-----GIPGRPG 1108

Query: 255  PQRPTPAPRLYYPLLLEHTLGLPAGK--AALAKAPVSPRSPSGTPAPGLLKVPVPGLGPW 312
            PQ P                  PAG+  A   K P  P    G   P  L  P   +GP 
Sbjct: 1109 PQGPPG----------------PAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVGP- 1151

Query: 313  PRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVM--- 369
                P + G +GE+      +P ++ S G + E     P+  +       P+G+      
Sbjct: 1152 ----PGEDGDKGEI-----GEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGADGEPGP 1202

Query: 370  -----LWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQ 424
                 L+ + GD G    PGP GP+ LQ    +PG P   GE      GD       +GQ
Sbjct: 1203 RGQQGLFGQKGDEGPRGFPGPPGPVGLQ---GLPGPPGEKGE-----TGD-------VGQ 1247

Query: 425  LGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQALGEAW 484
            +GP G   PR                         P  AP         A GPQ      
Sbjct: 1248 MGPPGPPGPR------------------------GPSGAP--------GADGPQGPPGGI 1275

Query: 485  GRP----ELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLPLAAPDDPVI 540
            G P    E G     G P  PG  GP  P+   G   +     +  PPG P   P D   
Sbjct: 1276 GNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAGPPG-PKGPPGDDGP 1334

Query: 541  PGS 543
             GS
Sbjct: 1335 KGS 1337



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 119/432 (27%), Positives = 150/432 (34%), Gaps = 54/432 (12%)

Query: 135  KGSPGPPPPVARATRKG-PGPSGLLPESWKPGMGGDPRGVG-AGDMASAGPEGSVPCYPP 192
            KG  GPP P       G PGPSG   E    G  G     G  G     GP G V     
Sbjct: 1173 KGEQGPPGPTGPQGPIGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGL 1232

Query: 193  PAP-GEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLP------- 244
            P P GE  E   +    +G   P  P      GPS A  A  P         P       
Sbjct: 1233 PGPPGEKGETGDV--GQMGPPGPPGPR-----GPSGAPGADGPQGPPGGIGNPGAVGEKG 1285

Query: 245  -PATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALA--KAPVSPRSPSGTPAPGL 301
             P  A     P +   P P+       E     P+G A     K P     P G+P P  
Sbjct: 1286 EPGEAGEPGLPGEGGPPGPKGERG---EKGESGPSGAAGPPGPKGPPGDDGPKGSPGP-- 1340

Query: 302  LKVPVPGLGPWPRVTPRDPGQEGEL-ERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRS 360
              V  PG  P P   P   GQ+G   ++    +P +  S G   E   + P   R     
Sbjct: 1341 --VGFPG-DPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGP 1397

Query: 361  SLPTGSSVMLWPEDGDPGGPETPGPEGPL----PLQPRGPVPGSPEHVGEDLTRALGDYA 416
            + P G         G+ G     G EGP     P+ P+G  PG P   G D  R +    
Sbjct: 1398 AGPEG-------RQGEKGAKGEAGLEGPPGKTGPIGPQG-APGKP---GPDGLRGIPGPV 1446

Query: 417  RVEQRL----GQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRA 472
              EQ L    G  GP G + P  L    G    +    H  L   + PP    +   +  
Sbjct: 1447 G-EQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGL 1505

Query: 473  PAKGPQALGEAWGRPEL-GPVLTGGTPEPPGMLGPAAPQPFSGHT--TKCEADSSVPPPG 529
            P  GPQ      G   + GP    G P PPG+ GP  P+   G +  T  + ++  P P 
Sbjct: 1506 P--GPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPP 1563

Query: 530  LPLAAPDDPVIP 541
             P   P + + P
Sbjct: 1564 GPPGPPGEVIQP 1575



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 136/529 (25%), Positives = 172/529 (32%), Gaps = 106/529 (20%)

Query: 78   RGSTTPRPHAPTPDRPGE--SDPGR-QPQGARPTGAAPAPDLVVADIHSLHCGG-GPKSR 133
            RG   P   A  P R G   SD  R  P    P G      L        H G  GP   
Sbjct: 594  RGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPS-- 651

Query: 134  AKGSPGPPPPVARATRKG----------PGPSGLLPESWKPGMGGDPRGVGAGDMASAGP 183
              G PGPP         G          PGP GLL     PG  G P GV   D    GP
Sbjct: 652  --GPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPP-GVTGMD-GQPGP 707

Query: 184  EGSV-PCYPPPAPGEF--PEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASAS 240
            +G+V P   P  PG+   P A  L            PG    +GP        P      
Sbjct: 708  KGNVGPQGEPGPPGQQGNPGAQGL------------PGPQGAIGPP---GEKGPLGKPGL 752

Query: 241  PLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPG 300
            P +P A       PP  P                G P  K    + P  P+ P G P P 
Sbjct: 753  PGMPGADG-----PPGHPGKE-------------GPPGEKGG--QGPPGPQGPIGYPGPR 792

Query: 301  LLKVP--VPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCS 358
             +K    + GL    + T  + G++G         P  +  +G + +  +  P   R   
Sbjct: 793  GVKGADGIRGL----KGTKGEKGEDGF--------PGFKGDMGIKGDRGEIGPPGPRGED 840

Query: 359  RSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQ----------PRGPV--PGSPEHVGE 406
                P G        +GDPG    PG +G L +           P+G +  PG P   GE
Sbjct: 841  GPEGPKGRG----GPNGDPGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGE 896

Query: 407  DLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLD 466
               R          + G  GP G   PR +  + G  +        A     R P+ P  
Sbjct: 897  KGGRGTPGKPGPRGQRGPTGPRGERGPRGITGKPGP-KGNSGGDGPAGPPGERGPNGPQG 955

Query: 467  LSVKRAPAKGPQA-------LGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKC 519
             +    P KGP          G    R E G     G P PPG++GP  P   +G T   
Sbjct: 956  PTGFPGP-KGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGP---TGETGPM 1011

Query: 520  EADSSVPPPGLPLAAPDDPVIPGSGWGTCVATRSSQTPEAVCGLQSPQG 568
                   PPG     P +  +PG        T+    P  + G   P G
Sbjct: 1012 GERGHPGPPG----PPGEQGLPGLAGKE--GTKGDPGPAGLPGKDGPPG 1054



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 91/331 (27%), Positives = 103/331 (31%), Gaps = 66/331 (19%)

Query: 87   APTPDRPGESDPGRQPQGAR-------PTGAAPAPDLVVADIHSLHCGGGPKSRA----- 134
            A  P  PGE  P   P+G R       P+GAA  P              GPK        
Sbjct: 1290 AGEPGLPGEGGPPG-PKGERGEKGESGPSGAAGPP--------------GPKGPPGDDGP 1334

Query: 135  KGSPGPP-------PPVARATRKGPGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSV 187
            KGSPGP        PP         GP G   +  +PG  G P     G     GP G  
Sbjct: 1335 KGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGDDGEPGQTGSP-----GPTGEPGPSGPP 1389

Query: 188  PCYPPPAPGEFPEAHSLHLSLLG-VNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPA 246
                PP P   PE         G       PG    +GP  A     P      P     
Sbjct: 1390 GKRGPPGPAG-PEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGE 1448

Query: 247  TAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPA-PGLLKVP 305
               P    P  P P P           +G P G   L K    P+   G P   GL+  P
Sbjct: 1449 QGLPGSPGPDGP-PGP-----------MG-PPGLPGL-KGDSGPKGEKGHPGLIGLIGPP 1494

Query: 306  VPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPTG 365
                    R  P   G  G       + P   +       LP   P   +    SS PTG
Sbjct: 1495 GEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLP--GPPGPKGAKGSSGPTG 1552

Query: 366  SSVMLWPEDGDPGGPETPGPEG----PLPLQ 392
                   E G PG P  PGP G    PLP+Q
Sbjct: 1553 PK----GEAGHPGPPGPPGPPGEVIQPLPIQ 1579



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 134/523 (25%), Positives = 159/523 (30%), Gaps = 73/523 (13%)

Query: 78   RGSTTPRPHAPTPDRPGESDPGRQ----PQGA-------RPTGAAPAPDLVVADIHSLHC 126
            +G+  P+     P + G  +PG Q    PQGA        P G    P +  AD    H 
Sbjct: 708  KGNVGPQGEPGPPGQQG--NPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHP 765

Query: 127  GGGPKSRAKGSPGPPPPVARATRKGP----GPSGLLPESWKPGMGGDPRGVG-AGDMASA 181
            G       KG  GPP P       GP    G  G+       G  G+    G  GDM   
Sbjct: 766  GKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGFPGFKGDMGIK 825

Query: 182  GPEGSVPCYPPPAPGEF-PEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASAS 240
            G  G +   PP   GE  PE         G   PL P       P       VP L    
Sbjct: 826  GDRGEIG--PPGPRGEDGPEGPKGRGGPNGDPGPLGP-------PGEKGKLGVPGLPG-- 874

Query: 241  PLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPG 300
                    +P  Q P+     P            G   G+    K    PR   G   P 
Sbjct: 875  --------YPGRQGPKGSIGFPGF------PGANGEKGGRGTPGKP--GPRGQRGPTGPR 918

Query: 301  LLKVPVPGLG-PWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSR 359
              + P    G P P+      G  G       + P+           PK  P       +
Sbjct: 919  GERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPG----PKGPPGPP---GK 971

Query: 360  SSLP----TGSSVMLWPEDGDPGGPETPGPEGPL----PLQPRGPVPGSPEHVGEDLTRA 411
              LP             + G PG P   GP+GP     P+  RG  PG P   GE   + 
Sbjct: 972  DGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGH-PGPPGPPGE---QG 1027

Query: 412  LGDYARVEQRLGQLGPAG---GLAPRPLREQLGKIRLELLTIHQALEQAVRPPD--APLD 466
            L   A  E   G  GPAG      P  LR   G   L        L+    PP    P  
Sbjct: 1028 LPGLAGKEGTKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAG 1087

Query: 467  LSVKRAPAKGPQALGEAWGRP-ELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSV 525
               +R PA     +G   GRP   GP    G    PG  GP  P    G           
Sbjct: 1088 SPGERGPAGAAGPIGIP-GRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPA 1146

Query: 526  PPPGLPLAAPDDPVIPGSGWGTCVATRSSQTPEAVCGLQSPQG 568
             P G P    D   I   G       +  Q P    G Q P G
Sbjct: 1147 GPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIG 1189



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 49/157 (31%), Positives = 62/157 (39%), Gaps = 14/157 (8%)

Query: 375 GDPGGPETPGPEGPL-PLQPRGPVPGSPEHVGED-LTRALGDYARVEQRLGQLGPAGGLA 432
           G PG P T GP G +     RGP PG P   G D L    G    +  R G  G AG   
Sbjct: 478 GLPGPPGTMGPTGQVGDPGERGP-PGRPGLPGADGLPGPPGTMLMLPFRFGGGGDAGSKG 536

Query: 433 PRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRPELGPV 492
           P    ++      +   I Q    A+R P  P+ L+ +  P  GP   G   G P  G V
Sbjct: 537 PMVSAQE-----SQAQAILQQARLALRGPAGPMGLTGRPGPV-GPPGSGGLKGEP--GDV 588

Query: 493 LTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPG 529
              G   P G+ GP  P    G   +  +D +   PG
Sbjct: 589 ---GPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPG 622



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 82/315 (26%), Positives = 104/315 (33%), Gaps = 76/315 (24%)

Query: 283 LAKAPVSPRSPSGTPAPGLLKVPVPGLG-PWPRVTPRDPGQEGELERAAQSDPRRRLSL- 340
           L + P  P  P+G P P     P   +G P  R  P  PG  G         P   L L 
Sbjct: 466 LIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPG--ADGLPGPPGTMLMLP 523

Query: 341 ---------GSRLELPKASPSLTRFCSRSSL--------PTGSSVMLWP-----EDGDPG 378
                    GS+  +  A  S  +   + +         P G +    P       G  G
Sbjct: 524 FRFGGGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKG 583

Query: 379 GPETPGPEGPLPLQ-PRGPV--PGSPEHVGEDLTRALGDYARVEQRLGQLGPAG-----G 430
            P   GP+GP  +Q P GP   PG     G D  R +          GQ GP G     G
Sbjct: 584 EPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMP---------GQTGPKGDRGFDG 634

Query: 431 LAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAK-GPQAL-GEAWGRPE 488
           LA  P  +            H+       PP  P D   +    + GP+ L GE   R  
Sbjct: 635 LAGLPGEKG-----------HRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGL 683

Query: 489 LGPVLTGGTPEPPGML------------------GPAAPQPFSGHTTKCEADSSVPPPGL 530
           LGP    G P PPG+                   GP   Q   G         ++ PPG 
Sbjct: 684 LGPKGPPGPPGPPGVTGMDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGE 743

Query: 531 --PLAAPDDPVIPGS 543
             PL  P  P +PG+
Sbjct: 744 KGPLGKPGLPGMPGA 758



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 40/126 (31%), Positives = 48/126 (38%), Gaps = 19/126 (15%)

Query: 85   PHAPTPDRP-GESDPGRQPQ---GARPTGAAPAPDLVVADIHSLHCGGGPKSRAKGSPGP 140
            P +P PD P G   P   P     + P G    P L+         G   +   KG  G 
Sbjct: 1452 PGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGL------IGPPGEQGEKGDRGL 1505

Query: 141  PPPVARATRKGP----GPSGLLPESWKPGMGGDPRGVGA-GDMASAGPEGSV----PCYP 191
            P P   +  KG     GPSG +     PG+ G P   GA G     GP+G      P  P
Sbjct: 1506 PGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKGSSGPTGPKGEAGHPGPPGP 1565

Query: 192  PPAPGE 197
            P  PGE
Sbjct: 1566 PGPPGE 1571


>gi|154759255 collagen, type XXVIII precursor [Homo sapiens]
          Length = 1125

 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 116/432 (26%), Positives = 149/432 (34%), Gaps = 89/432 (20%)

Query: 129 GPKSRA--KGSPGPPPPVARATRKGPGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGS 186
           GPK     KG PGPP P       G G  G+  E  + G  G P  +G G+    GP G 
Sbjct: 334 GPKGFQGNKGEPGPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPGPIGVGEPGQPGPRG- 392

Query: 187 VPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPS-------LAAAAHVPFLASA 239
               P   PGE          L G  +P   G     GP+       L+       +   
Sbjct: 393 ----PEGVPGE--------RGLPGEGFPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGPV 440

Query: 240 SPLLP---PATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAK-APVSPRSPSG 295
            P  P   P       Q  Q P   P    P       GLP  K  + +  P  PR P G
Sbjct: 441 GPQGPMGIPGIGSQGEQGIQGPIGPPGPQGPA----GQGLPGSKGEVGQMGPTGPRGPVG 496

Query: 296 TPA------PGLLKVP----VPG-------LGPWPRVTPRDP-GQEGELERAAQSDPRRR 337
                    PG + +P    VPG        G       R P G  G+ +   + D  ++
Sbjct: 497 IGVQGPKGEPGSIGLPGQPGVPGEDGAAGKKGEAGLPGARGPEGPPGKGQPGPKGDEGKK 556

Query: 338 LSLGSR-------LELPKASPSLTRFCSRSSLPTGSSVMLWP-EDGDPGGPETPGPEGPL 389
            S G++        E PK  P +        +P G+S+   P   GD GGP  PG +G  
Sbjct: 557 GSKGNQGQRGLPGPEGPKGEPGI---MGPFGMP-GTSIPGPPGPKGDRGGPGIPGFKGEP 612

Query: 390 PLQPRGP--VPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLEL 447
            L  RGP  V G    VG    +  G Y  V    G  GP G +  R + +   K     
Sbjct: 613 GLSIRGPKGVQGPRGPVGAPGLKGDG-YPGVPGPRGLPGPPGPMGLRGVGDTGAK----- 666

Query: 448 LTIHQALEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEPP-----G 502
                  E  VR P  P           GP+ +G    + + G     G P PP     G
Sbjct: 667 ------GEPGVRGPPGP----------SGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQG 710

Query: 503 MLGPAAPQPFSG 514
           + G   PQ F G
Sbjct: 711 IKGEQGPQGFPG 722



 Score = 36.2 bits (82), Expect = 0.083
 Identities = 46/155 (29%), Positives = 56/155 (36%), Gaps = 34/155 (21%)

Query: 79  GSTTPRPHAPTPDRPGESDPG---------RQPQGAR-PTGAAPAPDLV------VADIH 122
           G++ P P  P  DR G   PG         R P+G + P G   AP L       V    
Sbjct: 587 GTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGPKGVQGPRGPVGAPGLKGDGYPGVPGPR 646

Query: 123 SLHCGGGPK-------SRAKGSPG---PPPPVARATRKGPGPSGLLPESWKPGMGGDPRG 172
            L    GP        + AKG PG   PP P         GP G   +   PG  G P G
Sbjct: 647 GLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPP-G 705

Query: 173 VGA-------GDMASAGPEGSVPCYPPPAPGEFPE 200
            G+       G     GP+G++    P   GE  E
Sbjct: 706 YGSQGIKGEQGPQGFPGPKGTMGHGLPGQKGEHGE 740



 Score = 34.3 bits (77), Expect = 0.32
 Identities = 51/207 (24%), Positives = 67/207 (32%), Gaps = 38/207 (18%)

Query: 373 EDGDPGGPETPGPEG-PLPLQPRGPV--PGSPEHVGEDLTRALGDYARVEQRLGQLGPAG 429
           E GDPG P  PG  G P     RGP   PG+ +  GE   R  G     +   G+ G  G
Sbjct: 243 EKGDPGDPGPPGTHGNPGIKGERGPKGNPGNAQK-GEAGERGPGGIPGYKGDKGERGECG 301

Query: 430 GLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRPEL 489
               +  +   G                   P  P  +     P   P   G    + E 
Sbjct: 302 KPGIKGDKGSPGPY----------------GPKGPRGIQGITGPPGDPGPKGFQGNKGEP 345

Query: 490 GPVLTGGTPEPPGM------------LGPAAPQPFSGHTTKCEADSSVPPPGLPLAAPDD 537
           GP    G+P  PG+              P AP P          +   P P  P   P +
Sbjct: 346 GPPGPYGSPGAPGIGQQGIKGERGQEGRPGAPGPIG------VGEPGQPGPRGPEGVPGE 399

Query: 538 PVIPGSGWGTCVATRSSQTPEAVCGLQ 564
             +PG G+      + S+ P    GLQ
Sbjct: 400 RGLPGEGFPGPKGEKGSEGPTGPQGLQ 426



 Score = 32.0 bits (71), Expect = 1.6
 Identities = 53/199 (26%), Positives = 67/199 (33%), Gaps = 40/199 (20%)

Query: 375 GDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQLGPAG--GLA 432
           GD G P   GP+GP  +Q     PG P   G             +   G+ GP G  G  
Sbjct: 307 GDKGSPGPYGPKGPRGIQGITGPPGDPGPKG------------FQGNKGEPGPPGPYGSP 354

Query: 433 PRPLREQLGKIRLELLTIHQALEQAVRP-PDAPLDLSVKRAPA-KGPQALGEAWGRPELG 490
             P   Q G        I     Q  RP    P+ +     P  +GP+ +    G P  G
Sbjct: 355 GAPGIGQQG--------IKGERGQEGRPGAPGPIGVGEPGQPGPRGPEGVPGERGLPGEG 406

Query: 491 PVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLPLAAPDDPV-IPGSGWGTCV 549
                G     G  GP  PQ   G + K E     P        P  P+ IPG G     
Sbjct: 407 ---FPGPKGEKGSEGPTGPQGLQGLSIKGEKGDIGP------VGPQGPMGIPGIG----- 452

Query: 550 ATRSSQTPEAVCGLQSPQG 568
            ++  Q  +   G   PQG
Sbjct: 453 -SQGEQGIQGPIGPPGPQG 470



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 72/283 (25%), Positives = 92/283 (32%), Gaps = 58/283 (20%)

Query: 136 GSPGPPPPVARATRKGP-------GPSGLLPESWKPGMGGDPRGVGA----GDMASAGPE 184
           G PG P     A +KG        GP G  P   +PG  GD    G+    G     GPE
Sbjct: 513 GQPGVPGEDGAAGKKGEAGLPGARGPEGP-PGKGQPGPKGDEGKKGSKGNQGQRGLPGPE 571

Query: 185 GSVPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLG-PSLAAAAHVPFLASASPLL 243
           G  P   P   G F         + G + P  PG     G P +      P L+   P  
Sbjct: 572 G--PKGEPGIMGPF--------GMPGTSIPGPPGPKGDRGGPGIPGFKGEPGLSIRGP-- 619

Query: 244 PPATAFPAVQPPQRPTPAPRLY---YPLLLEHTLGLPAGKAAL---------AKAPVSPR 291
                   VQ P+ P  AP L    YP +     GLP     +         AK     R
Sbjct: 620 ------KGVQGPRGPVGAPGLKGDGYPGV-PGPRGLPGPPGPMGLRGVGDTGAKGEPGVR 672

Query: 292 SPSGTPAPGLLKVPVPGLGPWPRVTPRDPGQEG------ELERAAQSDPRRRLSLGSRLE 345
            P G   P  +    P      +  P  PG  G      + E+  Q  P  + ++G  L 
Sbjct: 673 GPPGPSGPRGVGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGPKGTMGHGLP 732

Query: 346 LPKASPSLTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGP 388
             K          R  +          E G+PG P   G +GP
Sbjct: 733 GQKGEHG-----ERGDVGKKGDK---GEIGEPGSPGKQGLQGP 767


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 65.1 bits (157), Expect = 2e-10
 Identities = 143/519 (27%), Positives = 173/519 (33%), Gaps = 87/519 (16%)

Query: 87  APTPDRPGESDPGRQPQGARPT-GAAPAPDLVVADIHSLHCGGGPKSRAKGSPGPPPPVA 145
           A  P RPGE  P   PQGAR   G A  P +        H G      AKG  GP  P  
Sbjct: 235 AGKPGRPGERGPPG-PQGARGLPGTAGLPGM------KGHRGFSGLDGAKGDAGPAGPKG 287

Query: 146 RATRKGP-------GPSGLLPESWKPGMGGDPRGVGAGDMAS--AGPEGSV-PCYPPPAP 195
                G        GP GL  E  +PG  G P G    D A+  AGP G   P  PP  P
Sbjct: 288 EPGSPGENGAPGQMGPRGLPGERGRPGAPG-PAGARGNDGATGAAGPPGPTGPAGPPGFP 346

Query: 196 GEF-------PEAHSLHLSLLGVN-YPLSPGLFSYLGPSLAAAAH-VPFL--ASASPLLP 244
           G         P+         GV   P  PG     GP+    A   P    A+ +P + 
Sbjct: 347 GAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIA 406

Query: 245 PATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAAL-AKAPVSPRSPSGTPAPGLLK 303
            A  FP  + P  P        P       G P  K    AK    P    G P P   +
Sbjct: 407 GAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEE 466

Query: 304 VPVPGLG-PWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSL 362
                 G P P   P  PG+ G         P  R   G+        P+  R     + 
Sbjct: 467 GKRGARGEPGPTGLPGPPGERG--------GPGSRGFPGADGVAGPKGPAGERGSPGPAG 518

Query: 363 PTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQRL 422
           P GS      E G PG    PG +G         + GSP   G D        A  + R 
Sbjct: 519 PKGSP----GEAGRPGEAGLPGAKG---------LTGSPGSPGPDGKTGPPGPAGQDGRP 565

Query: 423 GQLGPAGGL---------APRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVK--R 471
           G  GP G            P+    + GK          A E+ V  P   +  + K   
Sbjct: 566 GPPGPPGARGQAGVMGFPGPKGAAGEPGK----------AGERGVPGPPGAVGPAGKDGE 615

Query: 472 APAKGPQA-LGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGL 530
           A A+GP    G A  R E GP    G+P   G+ GPA P   +G   +      +  PG 
Sbjct: 616 AGAQGPPGPAGPAGERGEQGP---AGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPG- 671

Query: 531 PLAAPDDPVIPGSGWGTCVATRSSQTPEAVCGLQSPQGA 569
           P  A  +   PG         R  Q P    G +   GA
Sbjct: 672 PSGARGERGFPGE--------RGVQGPPGPAGPRGANGA 702



 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 127/438 (28%), Positives = 145/438 (33%), Gaps = 120/438 (27%)

Query: 79   GSTTPRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRAKGSP 138
            G   P   A  P   GES P      A PTGA  AP                    +G P
Sbjct: 767  GPIGPPGPAGAPGDKGESGPSGP---AGPTGARGAPG------------------DRGEP 805

Query: 139  GPPPPVARATRKGPGPSGLLPESWKPGMGGDPRGVGA-GDMASAGPEGSVPCYPPPAPGE 197
            GPP P   A     GP G      +PG  G+P   GA GD    GP G  P  PP   G 
Sbjct: 806  GPPGPAGFA-----GPPG---ADGQPGAKGEPGDAGAKGDAGPPGPAG--PAGPPGPIG- 854

Query: 198  FPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAFPAVQPPQR 257
                         V  P + G     GP  A      F  +A  + PP  +  A  PP  
Sbjct: 855  ------------NVGAPGAKGARGSAGPPGATG----FPGAAGRVGPPGPSGNA-GPPGP 897

Query: 258  PTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPGLLKVPVPGLGPWPRVTP 317
            P PA +       E   G P G+   A  P     P G P P   K   PG    P   P
Sbjct: 898  PGPAGK-------EGGKG-PRGETGPAGRP-GEVGPPGPPGPAGEK-GSPG-ADGPAGAP 946

Query: 318  RDPGQEGEL-ERAAQSDPRRRLSLG-SRLELPKASPSLTRFCSRSSLPTGSSVMLWPEDG 375
              PG +G   +R     P +R   G   L  P   P           P+G+S     E G
Sbjct: 947  GTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPG-------KQGPSGAS----GERG 995

Query: 376  DPGGPETPGPEGPLPLQPRGPVPGSPEHVGED-LTRALGDYARVEQRLGQLGPAGGLAPR 434
             PG    PG  GP     R   PG+    G D    A GD        G+ GPAG     
Sbjct: 996  PPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGD-------RGETGPAG----- 1043

Query: 435  PLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAP-AKGPQA-LGEAWGRPELGPV 492
                                     PP AP       AP A GP    G++  R E GP 
Sbjct: 1044 -------------------------PPGAP------GAPGAPGPVGPAGKSGDRGETGPA 1072

Query: 493  LTGGTPEPPGMLGPAAPQ 510
               G   P G  GPA PQ
Sbjct: 1073 GPAGPVGPVGARGPAGPQ 1090



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 93/331 (28%), Positives = 121/331 (36%), Gaps = 64/331 (19%)

Query: 129  GPKSRAKGSPGPPPPVARATRKGP----GPSGLLPESWKPGMGGDPRGVG-AGDMASAGP 183
            GP   A G PGPP P  +   KGP    GP+G      +PG  G P   G AG+  S G 
Sbjct: 887  GPSGNA-GPPGPPGPAGKEGGKGPRGETGPAG------RPGEVGPPGPPGPAGEKGSPGA 939

Query: 184  EGSVPCYPPPAPGEFPEAHSLHLSLLGV-------NYPLSPGLF---SYLGPSLAAAAHV 233
            +G  P   P  PG  P+  +    ++G+        +P  PG        GPS A+    
Sbjct: 940  DG--PAGAPGTPG--PQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERG 995

Query: 234  PFLASASPLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAAL-AKAPVSPRS 292
            P      P+ PP  A P  +  +   P              G P    +  AK       
Sbjct: 996  P----PGPMGPPGLAGPPGESGREGAPGAE-----------GSPGRDGSPGAKGDRGETG 1040

Query: 293  PSGTP-APGLLKVPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASP 351
            P+G P APG    P P +GP  +      G  GE   A  + P     +G       A P
Sbjct: 1041 PAGPPGAPGAPGAPGP-VGPAGK-----SGDRGETGPAGPAGP-----VGPVGARGPAGP 1089

Query: 352  SLTRFCSRSSLPTGSSVMLWPE-----DGDPGGPETPGPEGPL----PLQPRGPVPGSPE 402
               R     +   G   +          G PG P +PG +GP     P  PRGP PGS  
Sbjct: 1090 QGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGP-PGSAG 1148

Query: 403  HVGEDLTRALGDYARVEQRLGQLGPAGGLAP 433
              G+D    L          G+ G AG + P
Sbjct: 1149 APGKDGLNGLPGPIGPPGPRGRTGDAGPVGP 1179



 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 125/482 (25%), Positives = 157/482 (32%), Gaps = 109/482 (22%)

Query: 68  LLDSPDWACRRGSTTPRPHAPTPDRPGESDPGRQPQGAR----------PTGAA------ 111
           L  SP      G T P   A    RPG   PG  P GAR          P GAA      
Sbjct: 540 LTGSPGSPGPDGKTGPPGPAGQDGRPGP--PG--PPGARGQAGVMGFPGPKGAAGEPGKA 595

Query: 112 -----PAPDLVVADIHSLHCGGGPKSRAKGSPGPPPPVARATRKGP----------GPSG 156
                P P   V        G   ++ A+G PGP  P      +GP          GP+G
Sbjct: 596 GERGVPGPPGAVGP-----AGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAG 650

Query: 157 LLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCYPPPAPGE--FPEAHSLHLSLLGVNYP 214
              E+ KPG  G P     GD+ + GP G        A GE  FP          GV  P
Sbjct: 651 PPGEAGKPGEQGVP-----GDLGAPGPSG--------ARGERGFPGER-------GVQGP 690

Query: 215 LSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTL 274
             PG     G + A         + +P  P +   P +Q      P  R           
Sbjct: 691 --PGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQG----MPGER--------GAA 736

Query: 275 GLPAGKAALAKAPVSPRSPSGTPAP-GLLKVPVPGLGPWPRVTPRDPGQEGELERAAQSD 333
           GLP  K     A   P+   G+P   G+  +  P   P P   P D G+ G    A  + 
Sbjct: 737 GLPGPKGDRGDA--GPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTG 794

Query: 334 PRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPL-PLQ 392
            R   + G R E     P+       +    G+      E GD G     GP GP  P  
Sbjct: 795 ARG--APGDRGEPGPPGPAGFAGPPGADGQPGAK----GEPGDAGAKGDAGPPGPAGPAG 848

Query: 393 PRGPV-----PGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPR----PLREQLGKI 443
           P GP+     PG+    G         +     R+G  GP+G   P     P  ++ GK 
Sbjct: 849 PPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGK- 907

Query: 444 RLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEPPGM 503
                          R    P     +  P   P   GE       GP    GTP P G+
Sbjct: 908 -------------GPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGI 954

Query: 504 LG 505
            G
Sbjct: 955 AG 956



 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 131/481 (27%), Positives = 157/481 (32%), Gaps = 84/481 (17%)

Query: 75  ACRRGSTTPRPHAPTPD---RPGESD-PGRQPQGARPTGAAPAPDLVVADIHSLHCGGGP 130
           A  RGS  P     +P    RPGE+  PG +  G   +  +P PD             GP
Sbjct: 508 AGERGSPGPAGPKGSPGEAGRPGEAGLPGAK--GLTGSPGSPGPDGKTGP-------PGP 558

Query: 131 KSRAKGSPGPPPPVARATRKG----PGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGS 186
             +  G PGPP P     + G    PGP G   E  K G  G P   GA  +  AG +G 
Sbjct: 559 AGQ-DGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGA--VGPAGKDGE 615

Query: 187 VPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPS-------LAAAAHVPF-LAS 238
                PP P   P          G     SPG     GP+             VP  L +
Sbjct: 616 AGAQGPPGPAG-PAGERGEQGPAG-----SPGFQGLPGPAGPPGEAGKPGEQGVPGDLGA 669

Query: 239 ASPL-LPPATAFPA---VQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPS 294
             P        FP    VQ P  P   PR           G P    A   A  +P +P 
Sbjct: 670 PGPSGARGERGFPGERGVQGPPGPA-GPR--------GANGAPGNDGAKGDAG-APGAPG 719

Query: 295 GTPAPGLLKVP----VPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKAS 350
              APGL  +P      GL P P+    D G +G     A   P +    G    +    
Sbjct: 720 SQGAPGLQGMPGERGAAGL-PGPKGDRGDAGPKG-----ADGSPGKDGVRGLTGPIGPPG 773

Query: 351 PSLTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTR 410
           P+        S P+G +       G PG    PGP GP          G P   GE    
Sbjct: 774 PAGAPGDKGESGPSGPAGPTGAR-GAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEP--- 829

Query: 411 ALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVK 470
             GD A  +   G  GPAG   P      +G    +          +  PP A       
Sbjct: 830 --GD-AGAKGDAGPPGPAGPAGPPGPIGNVGAPGAK------GARGSAGPPGA------- 873

Query: 471 RAPAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGL 530
                 P A G   G P  GP    G P PPG  G    +   G T        V PPG 
Sbjct: 874 ---TGFPGAAGRV-GPP--GPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGP 927

Query: 531 P 531
           P
Sbjct: 928 P 928



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 130/522 (24%), Positives = 154/522 (29%), Gaps = 177/522 (33%)

Query: 76  CRRGSTTPRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRAK 135
           C  GS +P     T     + D G  P+G R     P  D +          G P     
Sbjct: 95  CPDGSESPTDQETTGVEGPKGDTG--PRGPRGPAGPPGRDGIP---------GQP----- 138

Query: 136 GSPGPPPPVARATRKGPGPSGLLPESWKPGMGG----------DPRGVGA----GDMASA 181
           G PGPP P        PGP G       PG+GG          D +  G     G M  +
Sbjct: 139 GLPGPPGP--------PGPPG------PPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPS 184

Query: 182 GPEGSVPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASP 241
           GP G     PP APG  P+             P  PG     GP          +    P
Sbjct: 185 GPRGLPG--PPGAPG--PQGFQ--------GPPGEPGEPGASGP----------MGPRGP 222

Query: 242 LLPPAT------AFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAAL-------AKAPV 288
             PP        A    +P +R  P P+    L    T GLP  K          AK   
Sbjct: 223 PGPPGKNGDDGEAGKPGRPGERGPPGPQGARGL--PGTAGLPGMKGHRGFSGLDGAKGDA 280

Query: 289 SPRSPSGTPAPGLLKVPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPK 348
            P  P G                       +PG  GE     Q  PR       R   P 
Sbjct: 281 GPAGPKG-----------------------EPGSPGENGAPGQMGPRGLPGERGRPGAPG 317

Query: 349 ASPSLTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDL 408
                         P G+       DG  G    PGP GP      GP PG P  VG   
Sbjct: 318 --------------PAGAR----GNDGATGAAGPPGPTGPA-----GP-PGFPGAVG--- 350

Query: 409 TRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLS 468
                     +   G  GP G   P+ +R + G                   P  P   +
Sbjct: 351 ---------AKGEAGPQGPRGSEGPQGVRGEPG-------------------PPGPAGAA 382

Query: 469 VKRAPAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPP 528
               PA  P A G+   +   G     G P  PG  GP+ PQ   G            PP
Sbjct: 383 ---GPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGG------------PP 427

Query: 529 GLPLAAPDDPVIPGSGWGTCVATRSSQTPEAVCGLQSPQGAE 570
           G P     +P  PGS   T    +    P  V G   P G E
Sbjct: 428 G-PKGNSGEPGAPGSKGDT--GAKGEPGPVGVQGPPGPAGEE 466



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 33/106 (31%), Positives = 37/106 (34%), Gaps = 26/106 (24%)

Query: 90   PDRPGESDPGRQ--PQGAR-PTGAAPAPDLVVADIHSLHCGGGPKSRAKGSPGPPPPVAR 146
            P  PGE  P     P G R P G+A AP                K    G PGP  P   
Sbjct: 1123 PGSPGEQGPSGASGPAGPRGPPGSAGAPG---------------KDGLNGLPGPIGP--- 1164

Query: 147  ATRKGPGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCYPP 192
                 PGP G   ++   G  G P   G     SAG + S    PP
Sbjct: 1165 -----PGPRGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPP 1205


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 122/488 (25%), Positives = 160/488 (32%), Gaps = 113/488 (23%)

Query: 90   PDRPGESDPGRQPQGA----RPTGAAPAPDLVVADIHSLHCGGGPKSRAKGSPGPPPPVA 145
            P  PGE  P + PQG      P G    P     D    H G   ++  +G  GPP P  
Sbjct: 924  PGPPGERGP-QGPQGPVGFPGPKGPPGPPG---KDGLPGHPGQRGETGFQGKTGPPGPGG 979

Query: 146  RATRKGP-GPSGLLPESWKPGMGGDPRGVGA-------GDMASAGPEGSVPCYPPPAPGE 197
                +GP G +G + E   PG  G P   G        G     GP+G      P     
Sbjct: 980  VVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRG 1039

Query: 198  FPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAFPAVQPPQR 257
            FP    L           +PGL    GP          + S        TA P +  P R
Sbjct: 1040 FPGERGLP------GAQGAPGLKGGEGPQGPPGP----VGSPGERGSAGTAGP-IGLPGR 1088

Query: 258  PTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPGLLKVPVPGLGP-WPRVT 316
            P P                P G A    AP   + P G      ++ PV   GP  P  +
Sbjct: 1089 PGPQG--------------PPGPAGEKGAP-GEKGPQGPAGRDGVQGPVGLPGPAGPAGS 1133

Query: 317  PRDPGQEGELERAAQSDPRRRLSLGSRLEL-PKASPSLTRFCSRSSLPTGSSVM------ 369
            P + G +GE+      +P ++ S G + E  P   P L        +  G          
Sbjct: 1134 PGEDGDKGEI-----GEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQ 1188

Query: 370  -LWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQLGPA 428
             ++ + GD G    PGP GP+ LQ    +PG P   GE+     GD       +G +GP 
Sbjct: 1189 GMFGQKGDEGARGFPGPPGPIGLQG---LPGPPGEKGEN-----GD-------VGPMGPP 1233

Query: 429  GGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRPE 488
            G   PR                          P  P      + P   P ++G   G  E
Sbjct: 1234 GPPGPRG-------------------------PQGPNGADGPQGP---PGSVGSVGGVGE 1265

Query: 489  LGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGL--------------PLAA 534
             G     G P PPG  G   P+   G   +     +  PPG               P+  
Sbjct: 1266 KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF 1325

Query: 535  PDDPVIPG 542
            P DP  PG
Sbjct: 1326 PGDPGPPG 1333



 Score = 59.3 bits (142), Expect = 9e-09
 Identities = 111/415 (26%), Positives = 142/415 (34%), Gaps = 82/415 (19%)

Query: 134  AKGSPGPPPPVARATRKGP----GPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPC 189
            A+G PGPP P+      GP    G +G +     PG  G PRG   G   + GP+G    
Sbjct: 1199 ARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG-PRGP-QGPNGADGPQG---- 1252

Query: 190  YPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPF--LASASPLLPPAT 247
             PP + G          S+ GV     PG     GP   A    P           PP  
Sbjct: 1253 -PPGSVG----------SVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGA 1301

Query: 248  AFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPGLLKVPVP 307
            A P                                 AK P     P G P P    V  P
Sbjct: 1302 AGPPG-------------------------------AKGPPGDDGPKGNPGP----VGFP 1326

Query: 308  GLGPWPRVTPRDPGQEGEL-ERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPTGS 366
            G  P P   P   GQ+G   ++    DP +    G   E     P   R    ++   G 
Sbjct: 1327 G-DPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEG- 1384

Query: 367  SVMLWPEDGDPGGPETPGPEGPL----PLQPRGPVPGSPEHVG-EDLTRALGDYARVEQR 421
                    G+ G     G EGP     P+ P+GP  G P   G   +   +G+   +   
Sbjct: 1385 ------RQGEKGAKGEAGAEGPPGKTGPVGPQGPA-GKPGPEGLRGIPGPVGEQG-LPGA 1436

Query: 422  LGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAK--GPQA 479
             GQ GP G + P  L    G    +    H  L   + PP    +   +  P     P A
Sbjct: 1437 AGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGA 1496

Query: 480  LGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKC--EADSSVP-PPGLP 531
             G+  G P  GP    G P PPG+ GP  P+   G T     + DS +P PPG P
Sbjct: 1497 KGDG-GIP--GPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSP 1548



 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 120/455 (26%), Positives = 156/455 (34%), Gaps = 74/455 (16%)

Query: 83  PRPHAPT--PDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPK----SRAKG 136
           P    PT  P  PG+  P  +P G       P P   +  +   + G G K    S  + 
Sbjct: 468 PGLQGPTGPPGDPGDRGPPGRP-GLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEA 526

Query: 137 SPGPPPPVARATRKGP-GPSGLLPESWKPGMGGDPRGVGA-GDMASAGPEGSVPCYPPPA 194
                   AR   +GP GP GL   + +PG  G P   GA G+    GP+G      PP 
Sbjct: 527 QAQAILQQARIALRGPPGPMGL---TGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPG 583

Query: 195 PGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAFPAVQP 254
           P   P       +  G   P  PG     G                P LP        + 
Sbjct: 584 PTGKPGKRGRPGADGGRGMPGEPGAKGDRG------------FDGLPGLPGDKGHRGERG 631

Query: 255 PQRPTPAPRLYYPLLLEH----TLGLPAGKAALAKAPVSPRSPSGTPA-PGLLKV---PV 306
           PQ P P P     +  E       GLP G+A   +  + PR   G P  PG+  V   P 
Sbjct: 632 PQGP-PGPPGDDGMRGEDGEIGPRGLP-GEAG-PRGLLGPRGTPGAPGQPGMAGVDGPPG 688

Query: 307 PGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLEL-PKASPSLTRFCSRSSLPTG 365
           P     P+  P  PGQ+G      Q  P  +  +G   E  P+  P L      + LP  
Sbjct: 689 PKGNMGPQGEPGPPGQQG--NPGPQGLPGPQGPIGPPGEKGPQGKPGL------AGLPGA 740

Query: 366 SSVMLWPEDGDPGGPETPGPEGPL----PLQPRGPV--PGSPEHVGEDLTRALGDYARVE 419
                   DG PG P   G  G      P  P+GP+  PG     G D  R L      +
Sbjct: 741 --------DGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEK 792

Query: 420 QRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQA 479
              G  G  G +  +  R ++G+I               R  D P     +  P   P  
Sbjct: 793 GEDGFPGFKGDMGLKGDRGEVGQI-------------GPRGEDGPEGPKGRAGPTGDPGP 839

Query: 480 LGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSG 514
            G+A  + +LG     G P  PG  GP     F G
Sbjct: 840 SGQAGEKGKLG---VPGLPGYPGRQGPKGSTGFPG 871



 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 143/553 (25%), Positives = 177/553 (32%), Gaps = 110/553 (19%)

Query: 79   GSTTP---RPHAPTPDRPGES-------------DPGRQ-------PQGARP-------T 108
            G T P   R H   P  PGE              DPG Q       P G R         
Sbjct: 988  GETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLP 1047

Query: 109  GAAPAPDLVVADIHSLHCGGGPKSRAKGSPGPPPPVARATRKGP-GPSGLLPESWKPGMG 167
            GA  AP L   +      G       +GS G   P+    R GP GP G   E   PG  
Sbjct: 1048 GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEK 1107

Query: 168  GDPRGVGAGDMASAGPEGSV-PCYPPPAPGEFPEAHSL-------HLSLLGVNYPLSP-G 218
            G P+G  AG     GP G   P  P  +PGE  +   +            G N P  P G
Sbjct: 1108 G-PQGP-AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG 1165

Query: 219  LFSYLG-PSLAAAAHVPFLASASPLLPP-----ATAFPAVQPPQRPTPAPRLYYPLLLEH 272
            L   +G P +A     P       +        A  FP   PP           P+ L+ 
Sbjct: 1166 LQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG--PPG----------PIGLQG 1213

Query: 273  TLGLPAGKAALAKAPVSPRSPSGTPAPGLLKVP---------------VPGLG----PWP 313
              G P  K       V P  P G P P   + P               V G+G    P  
Sbjct: 1214 LPGPPGEKGE--NGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGE 1271

Query: 314  RVTPRDPGQEG-------ELERAAQSDPRRRLSLGSRL----ELPKASPSLTRFCSRSSL 362
               P  PG+ G         E+     P      G++     + PK +P    F      
Sbjct: 1272 AGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGP 1331

Query: 363  P-----TGSSVMLWP--EDGDPGGPETPGPEG----PLPLQPRGPVPGSPEHVGEDLTRA 411
            P      G   +     EDGDPG P  PGP G    P P   RGP PG+    G    + 
Sbjct: 1332 PGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGP-PGAAGAEGRQGEKG 1390

Query: 412  LGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKR 471
                A  E   G+ GP G   P       G   +      Q L  A      P  +    
Sbjct: 1391 AKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPM---- 1446

Query: 472  APAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQ--PFSGHTTKCEADSSVPPPG 529
             P   P   G+   + E G     G   PPG  G    +  P +  +   + D  +P P 
Sbjct: 1447 GPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPA 1506

Query: 530  LPLAAPDDPVIPG 542
             PL  P  P +PG
Sbjct: 1507 GPLGPPGPPGLPG 1519



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 134/531 (25%), Positives = 169/531 (31%), Gaps = 119/531 (22%)

Query: 93   PGESDPGRQPQGARPTGAAPA-PDLVVADIHSLHCGGGPKSRA--KGSPGPPPPVARATR 149
            PGE+ P R   G R T  AP  P +   D        GPK     +G PGPP        
Sbjct: 657  PGEAGP-RGLLGPRGTPGAPGQPGMAGVDGPP-----GPKGNMGPQGEPGPPGQQGNPGP 710

Query: 150  KG-PGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCYPPPAPGEFPEAHSLHLSL 208
            +G PGP G +    + G  G P   G       G +G     PP  PG+  E  S     
Sbjct: 711  QGLPGPQGPIGPPGEKGPQGKPGLAGL-----PGADG-----PPGHPGK--EGQSGEKGA 758

Query: 209  LGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAFPAVQPPQRPTPAPRLYYPL 268
            LG   P  P    Y GP     A        S        FP                  
Sbjct: 759  LGPPGPQGP--IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG----------------- 799

Query: 269  LLEHTLGLPAGKAALAK-------APVSPRS---PSGTPAPGLL-----KVPVPGLGPWP 313
              +  +GL   +  + +        P  P+    P+G P P        K+ VPGL  +P
Sbjct: 800  -FKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYP 858

Query: 314  -RVTPRD-------PGQEGEL-ERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPT 364
             R  P+        PG  GE   R     P  R   G R           R  +    P 
Sbjct: 859  GRQGPKGSTGFPGFPGANGEKGARGVAGKPGPR---GQRGPTGPRGSRGARGPTGKPGPK 915

Query: 365  GSSVMLWPEDGDPGGPETPGPEGPL-------PLQPRGP-----VPGSPEHVGEDLTRAL 412
            G+S      DG PG P   GP+GP        P  P GP     +PG P   GE      
Sbjct: 916  GTS----GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGE------ 965

Query: 413  GDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRA 472
                  + + G  GP G + P+    + G I                PP  P +  +  A
Sbjct: 966  ---TGFQGKTGPPGPGGVVGPQGPTGETGPI---------GERGHPGPPGPPGEQGLPGA 1013

Query: 473  PAK-------GPQALGEAWGRP-------ELGPVLTGGTPEPPGMLGPAAPQPFSGHTTK 518
              K       GPQ +    G         E G     G P   G  GP  P    G   +
Sbjct: 1014 AGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGE 1073

Query: 519  CEADSSVPPPGLP-LAAPDDPVIPGSGWGTCVATRSSQTPEAVCGLQSPQG 568
              +  +  P GLP    P  P  P    G     +  Q P    G+Q P G
Sbjct: 1074 RGSAGTAGPIGLPGRPGPQGPPGPAGEKG-APGEKGPQGPAGRDGVQGPVG 1123



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 126/501 (25%), Positives = 164/501 (32%), Gaps = 79/501 (15%)

Query: 127  GGGPKSRAKGSPGPPPPVA-RATRKGPGPSGLLPESWKP------GMGGDPRGVG----- 174
            GG   S AKG  G P P   R  +  PGP+G   +  +P      GM G+P   G     
Sbjct: 556  GGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFD 615

Query: 175  -----AGDMASAGPEGSVPCYPPPAPG-EFPEAHSLHLSLLGVNYPLSPGLFSYLGP-SL 227
                  GD    G  G  P  PP  PG +        +   G+  P   G    LGP   
Sbjct: 616  GLPGLPGDKGHRGERG--PQGPPGPPGDDGMRGEDGEIGPRGL--PGEAGPRGLLGPRGT 671

Query: 228  AAAAHVPFLASA-SPLLPPATAFPAVQP----------------PQRPTPAPRLYYPLLL 270
              A   P +A    P  P     P  +P                PQ P   P    P   
Sbjct: 672  PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 731

Query: 271  EHTLGLPA--------GKAAL-----AKAPVSPRSPSGTPAPGLLKVP--VPGLGPWPRV 315
                GLP         GK        A  P  P+ P G P P  +K    V GL      
Sbjct: 732  PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGE 791

Query: 316  TPRD--PGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVMLWPE 373
               D  PG +G++    + D      +G R E     P      +    P+G +     +
Sbjct: 792  KGEDGFPGFKGDM--GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEK-GK 848

Query: 374  DGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAP 433
             G PG P  PG +GP   +     PG P   GE   R +   A      GQ GP G    
Sbjct: 849  LGVPGLPGYPGRQGP---KGSTGFPGFPGANGEKGARGV---AGKPGPRGQRGPTGPRGS 902

Query: 434  RPLREQLGKIRLELLTIHQAL-----EQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRP- 487
            R  R   GK   +  +          E+  + P  P+     + P  GP       G P 
Sbjct: 903  RGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGP-PGPPGKDGLPGHPG 961

Query: 488  ELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLPLAAPDDPVIPGSGWGT 547
            + G     G   PPG  G   PQ  +G T          PPG     P +  +PG+    
Sbjct: 962  QRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG----PPGEQGLPGAAGKE 1017

Query: 548  CVATRSSQTPEAVCGLQSPQG 568
                +    P+ + G   P G
Sbjct: 1018 --GAKGDPGPQGISGKDGPAG 1036



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 52/183 (28%), Positives = 66/183 (36%), Gaps = 38/183 (20%)

Query: 375 GDPGGPETPGPEGPLPLQP--RGPVPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLA 432
           G  G P   GP GP P  P  RGP PG P   G D               G  GP G + 
Sbjct: 463 GIMGPPGLQGPTGP-PGDPGDRGP-PGRPGLPGAD---------------GLPGPPGTML 505

Query: 433 PRPLREQLGKIRLELLTIHQALEQAV--------RPPDAPLDLSVKRAPAKGPQALGEAW 484
             P R      +   ++  +A  QA+        R P  P+ L+ +  P  GP + G   
Sbjct: 506 MLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKG 565

Query: 485 GRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLPLAAPDD-----PV 539
              + GP        P G+ GP  P    G   +  AD     PG P A  D      P 
Sbjct: 566 ESGDPGP------QGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPG 619

Query: 540 IPG 542
           +PG
Sbjct: 620 LPG 622



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 78/292 (26%), Positives = 100/292 (34%), Gaps = 53/292 (18%)

Query: 283 LAKAPVSPRSPSGTPAPGLLKVPV-PGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSL- 340
           L + P  P  P+G   P  L+ P  P   P  R  P  PG  G         P   L L 
Sbjct: 451 LVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGA--DGLPGPPGTMLMLP 508

Query: 341 ---------GSRLELPKASPSLTRFCSRSSLPTGSSVM-LWPEDGDPGGPET-------- 382
                    G  +   +A        +R +L      M L    G  GGP +        
Sbjct: 509 FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 568

Query: 383 -PGPEGPLPLQ-PRGPV--PGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLRE 438
            PGP+GP  +Q P GP   PG     G D  R +      +   G  G  G    +  R 
Sbjct: 569 DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRG 628

Query: 439 QLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAK-GPQAL-GEAWGRPELGPVLTGG 496
           + G                  PP  P D  ++    + GP+ L GEA  R  LGP  T G
Sbjct: 629 ERGP---------------QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPG 673

Query: 497 TPEPPGMLGPAAPQPFSGHTTKCEADSSVP-------PPGLPLAAPDDPVIP 541
            P  PGM G   P    G+    + +   P       P GLP   P  P+ P
Sbjct: 674 APGQPGMAGVDGPPGPKGNMGP-QGEPGPPGQQGNPGPQGLP--GPQGPIGP 722



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 64/232 (27%), Positives = 81/232 (34%), Gaps = 39/232 (16%)

Query: 90   PDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRAKGSPGPPPPVARATR 149
            P +PG   P  +     P G    P    A+      G   ++ A+G PG   PV     
Sbjct: 1353 PGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGP 1412

Query: 150  KG-PGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCYPPPAPGEFPEAHSL---- 204
             G PGP GL       G  G P   G       GP G  P  PP  PG   +  S     
Sbjct: 1413 AGKPGPEGLRGIPGPVGEQGLPGAAG-----QDGPPG--PMGPPGLPGLKGDPGSKGEKG 1465

Query: 205  HLSLLGVNYPLSPGLFSYLG----------PSLAAAAHVPFLASASPLLPPATAFPAVQP 254
            H  L+G+  P  PG     G          P       +P    A PL PP        P
Sbjct: 1466 HPGLIGLIGP--PGEQGEKGDRGLPGTQGSPGAKGDGGIP--GPAGPLGPPG-------P 1514

Query: 255  PQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPGLLKVPV 306
            P  P P      P   + + G PAG+   +  P  P SP G P   +  +P+
Sbjct: 1515 PGLPGPQG----PKGNKGSTG-PAGQKGDSGLPGPPGSP-GPPGEVIQPLPI 1560


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 122/488 (25%), Positives = 160/488 (32%), Gaps = 113/488 (23%)

Query: 90   PDRPGESDPGRQPQGA----RPTGAAPAPDLVVADIHSLHCGGGPKSRAKGSPGPPPPVA 145
            P  PGE  P + PQG      P G    P     D    H G   ++  +G  GPP P  
Sbjct: 873  PGPPGERGP-QGPQGPVGFPGPKGPPGPPG---KDGLPGHPGQRGETGFQGKTGPPGPGG 928

Query: 146  RATRKGP-GPSGLLPESWKPGMGGDPRGVGA-------GDMASAGPEGSVPCYPPPAPGE 197
                +GP G +G + E   PG  G P   G        G     GP+G      P     
Sbjct: 929  VVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRG 988

Query: 198  FPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAFPAVQPPQR 257
            FP    L           +PGL    GP          + S        TA P +  P R
Sbjct: 989  FPGERGLP------GAQGAPGLKGGEGPQGPPGP----VGSPGERGSAGTAGP-IGLPGR 1037

Query: 258  PTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPGLLKVPVPGLGP-WPRVT 316
            P P                P G A    AP   + P G      ++ PV   GP  P  +
Sbjct: 1038 PGPQG--------------PPGPAGEKGAP-GEKGPQGPAGRDGVQGPVGLPGPAGPAGS 1082

Query: 317  PRDPGQEGELERAAQSDPRRRLSLGSRLEL-PKASPSLTRFCSRSSLPTGSSVM------ 369
            P + G +GE+      +P ++ S G + E  P   P L        +  G          
Sbjct: 1083 PGEDGDKGEI-----GEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQ 1137

Query: 370  -LWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQLGPA 428
             ++ + GD G    PGP GP+ LQ    +PG P   GE+     GD       +G +GP 
Sbjct: 1138 GMFGQKGDEGARGFPGPPGPIGLQG---LPGPPGEKGEN-----GD-------VGPMGPP 1182

Query: 429  GGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRPE 488
            G   PR                          P  P      + P   P ++G   G  E
Sbjct: 1183 GPPGPRG-------------------------PQGPNGADGPQGP---PGSVGSVGGVGE 1214

Query: 489  LGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGL--------------PLAA 534
             G     G P PPG  G   P+   G   +     +  PPG               P+  
Sbjct: 1215 KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF 1274

Query: 535  PDDPVIPG 542
            P DP  PG
Sbjct: 1275 PGDPGPPG 1282



 Score = 59.3 bits (142), Expect = 9e-09
 Identities = 111/415 (26%), Positives = 142/415 (34%), Gaps = 82/415 (19%)

Query: 134  AKGSPGPPPPVARATRKGP----GPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPC 189
            A+G PGPP P+      GP    G +G +     PG  G PRG   G   + GP+G    
Sbjct: 1148 ARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG-PRGP-QGPNGADGPQG---- 1201

Query: 190  YPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPF--LASASPLLPPAT 247
             PP + G          S+ GV     PG     GP   A    P           PP  
Sbjct: 1202 -PPGSVG----------SVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGA 1250

Query: 248  AFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPGLLKVPVP 307
            A P                                 AK P     P G P P    V  P
Sbjct: 1251 AGPPG-------------------------------AKGPPGDDGPKGNPGP----VGFP 1275

Query: 308  GLGPWPRVTPRDPGQEGEL-ERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPTGS 366
            G  P P   P   GQ+G   ++    DP +    G   E     P   R    ++   G 
Sbjct: 1276 G-DPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEG- 1333

Query: 367  SVMLWPEDGDPGGPETPGPEGPL----PLQPRGPVPGSPEHVG-EDLTRALGDYARVEQR 421
                    G+ G     G EGP     P+ P+GP  G P   G   +   +G+   +   
Sbjct: 1334 ------RQGEKGAKGEAGAEGPPGKTGPVGPQGPA-GKPGPEGLRGIPGPVGEQG-LPGA 1385

Query: 422  LGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAK--GPQA 479
             GQ GP G + P  L    G    +    H  L   + PP    +   +  P     P A
Sbjct: 1386 AGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGA 1445

Query: 480  LGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKC--EADSSVP-PPGLP 531
             G+  G P  GP    G P PPG+ GP  P+   G T     + DS +P PPG P
Sbjct: 1446 KGDG-GIP--GPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSP 1497



 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 120/455 (26%), Positives = 156/455 (34%), Gaps = 74/455 (16%)

Query: 83  PRPHAPT--PDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPK----SRAKG 136
           P    PT  P  PG+  P  +P G       P P   +  +   + G G K    S  + 
Sbjct: 417 PGLQGPTGPPGDPGDRGPPGRP-GLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEA 475

Query: 137 SPGPPPPVARATRKGP-GPSGLLPESWKPGMGGDPRGVGA-GDMASAGPEGSVPCYPPPA 194
                   AR   +GP GP GL   + +PG  G P   GA G+    GP+G      PP 
Sbjct: 476 QAQAILQQARIALRGPPGPMGL---TGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPG 532

Query: 195 PGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAFPAVQP 254
           P   P       +  G   P  PG     G                P LP        + 
Sbjct: 533 PTGKPGKRGRPGADGGRGMPGEPGAKGDRG------------FDGLPGLPGDKGHRGERG 580

Query: 255 PQRPTPAPRLYYPLLLEH----TLGLPAGKAALAKAPVSPRSPSGTPA-PGLLKV---PV 306
           PQ P P P     +  E       GLP G+A   +  + PR   G P  PG+  V   P 
Sbjct: 581 PQGP-PGPPGDDGMRGEDGEIGPRGLP-GEAG-PRGLLGPRGTPGAPGQPGMAGVDGPPG 637

Query: 307 PGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLEL-PKASPSLTRFCSRSSLPTG 365
           P     P+  P  PGQ+G      Q  P  +  +G   E  P+  P L      + LP  
Sbjct: 638 PKGNMGPQGEPGPPGQQG--NPGPQGLPGPQGPIGPPGEKGPQGKPGL------AGLPGA 689

Query: 366 SSVMLWPEDGDPGGPETPGPEGPL----PLQPRGPV--PGSPEHVGEDLTRALGDYARVE 419
                   DG PG P   G  G      P  P+GP+  PG     G D  R L      +
Sbjct: 690 --------DGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEK 741

Query: 420 QRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQA 479
              G  G  G +  +  R ++G+I               R  D P     +  P   P  
Sbjct: 742 GEDGFPGFKGDMGLKGDRGEVGQI-------------GPRGEDGPEGPKGRAGPTGDPGP 788

Query: 480 LGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSG 514
            G+A  + +LG     G P  PG  GP     F G
Sbjct: 789 SGQAGEKGKLG---VPGLPGYPGRQGPKGSTGFPG 820



 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 143/553 (25%), Positives = 177/553 (32%), Gaps = 110/553 (19%)

Query: 79   GSTTP---RPHAPTPDRPGES-------------DPGRQ-------PQGARP-------T 108
            G T P   R H   P  PGE              DPG Q       P G R         
Sbjct: 937  GETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLP 996

Query: 109  GAAPAPDLVVADIHSLHCGGGPKSRAKGSPGPPPPVARATRKGP-GPSGLLPESWKPGMG 167
            GA  AP L   +      G       +GS G   P+    R GP GP G   E   PG  
Sbjct: 997  GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEK 1056

Query: 168  GDPRGVGAGDMASAGPEGSV-PCYPPPAPGEFPEAHSL-------HLSLLGVNYPLSP-G 218
            G P+G  AG     GP G   P  P  +PGE  +   +            G N P  P G
Sbjct: 1057 G-PQGP-AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG 1114

Query: 219  LFSYLG-PSLAAAAHVPFLASASPLLPP-----ATAFPAVQPPQRPTPAPRLYYPLLLEH 272
            L   +G P +A     P       +        A  FP   PP           P+ L+ 
Sbjct: 1115 LQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG--PPG----------PIGLQG 1162

Query: 273  TLGLPAGKAALAKAPVSPRSPSGTPAPGLLKVP---------------VPGLG----PWP 313
              G P  K       V P  P G P P   + P               V G+G    P  
Sbjct: 1163 LPGPPGEKGE--NGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGE 1220

Query: 314  RVTPRDPGQEG-------ELERAAQSDPRRRLSLGSRL----ELPKASPSLTRFCSRSSL 362
               P  PG+ G         E+     P      G++     + PK +P    F      
Sbjct: 1221 AGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGP 1280

Query: 363  P-----TGSSVMLWP--EDGDPGGPETPGPEG----PLPLQPRGPVPGSPEHVGEDLTRA 411
            P      G   +     EDGDPG P  PGP G    P P   RGP PG+    G    + 
Sbjct: 1281 PGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGP-PGAAGAEGRQGEKG 1339

Query: 412  LGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKR 471
                A  E   G+ GP G   P       G   +      Q L  A      P  +    
Sbjct: 1340 AKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPM---- 1395

Query: 472  APAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQ--PFSGHTTKCEADSSVPPPG 529
             P   P   G+   + E G     G   PPG  G    +  P +  +   + D  +P P 
Sbjct: 1396 GPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPA 1455

Query: 530  LPLAAPDDPVIPG 542
             PL  P  P +PG
Sbjct: 1456 GPLGPPGPPGLPG 1468



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 134/531 (25%), Positives = 169/531 (31%), Gaps = 119/531 (22%)

Query: 93   PGESDPGRQPQGARPTGAAPA-PDLVVADIHSLHCGGGPKSRA--KGSPGPPPPVARATR 149
            PGE+ P R   G R T  AP  P +   D        GPK     +G PGPP        
Sbjct: 606  PGEAGP-RGLLGPRGTPGAPGQPGMAGVDGPP-----GPKGNMGPQGEPGPPGQQGNPGP 659

Query: 150  KG-PGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCYPPPAPGEFPEAHSLHLSL 208
            +G PGP G +    + G  G P   G       G +G     PP  PG+  E  S     
Sbjct: 660  QGLPGPQGPIGPPGEKGPQGKPGLAGL-----PGADG-----PPGHPGK--EGQSGEKGA 707

Query: 209  LGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAFPAVQPPQRPTPAPRLYYPL 268
            LG   P  P    Y GP     A        S        FP                  
Sbjct: 708  LGPPGPQGP--IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG----------------- 748

Query: 269  LLEHTLGLPAGKAALAK-------APVSPRS---PSGTPAPGLL-----KVPVPGLGPWP 313
              +  +GL   +  + +        P  P+    P+G P P        K+ VPGL  +P
Sbjct: 749  -FKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYP 807

Query: 314  -RVTPRD-------PGQEGEL-ERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPT 364
             R  P+        PG  GE   R     P  R   G R           R  +    P 
Sbjct: 808  GRQGPKGSTGFPGFPGANGEKGARGVAGKPGPR---GQRGPTGPRGSRGARGPTGKPGPK 864

Query: 365  GSSVMLWPEDGDPGGPETPGPEGPL-------PLQPRGP-----VPGSPEHVGEDLTRAL 412
            G+S      DG PG P   GP+GP        P  P GP     +PG P   GE      
Sbjct: 865  GTS----GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGE------ 914

Query: 413  GDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRA 472
                  + + G  GP G + P+    + G I                PP  P +  +  A
Sbjct: 915  ---TGFQGKTGPPGPGGVVGPQGPTGETGPI---------GERGHPGPPGPPGEQGLPGA 962

Query: 473  PAK-------GPQALGEAWGRP-------ELGPVLTGGTPEPPGMLGPAAPQPFSGHTTK 518
              K       GPQ +    G         E G     G P   G  GP  P    G   +
Sbjct: 963  AGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGE 1022

Query: 519  CEADSSVPPPGLP-LAAPDDPVIPGSGWGTCVATRSSQTPEAVCGLQSPQG 568
              +  +  P GLP    P  P  P    G     +  Q P    G+Q P G
Sbjct: 1023 RGSAGTAGPIGLPGRPGPQGPPGPAGEKG-APGEKGPQGPAGRDGVQGPVG 1072



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 126/501 (25%), Positives = 164/501 (32%), Gaps = 79/501 (15%)

Query: 127 GGGPKSRAKGSPGPPPPVA-RATRKGPGPSGLLPESWKP------GMGGDPRGVG----- 174
           GG   S AKG  G P P   R  +  PGP+G   +  +P      GM G+P   G     
Sbjct: 505 GGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFD 564

Query: 175 -----AGDMASAGPEGSVPCYPPPAPG-EFPEAHSLHLSLLGVNYPLSPGLFSYLGP-SL 227
                 GD    G  G  P  PP  PG +        +   G+  P   G    LGP   
Sbjct: 565 GLPGLPGDKGHRGERG--PQGPPGPPGDDGMRGEDGEIGPRGL--PGEAGPRGLLGPRGT 620

Query: 228 AAAAHVPFLASA-SPLLPPATAFPAVQP----------------PQRPTPAPRLYYPLLL 270
             A   P +A    P  P     P  +P                PQ P   P    P   
Sbjct: 621 PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 680

Query: 271 EHTLGLPA--------GKAAL-----AKAPVSPRSPSGTPAPGLLKVP--VPGLGPWPRV 315
               GLP         GK        A  P  P+ P G P P  +K    V GL      
Sbjct: 681 PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGE 740

Query: 316 TPRD--PGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVMLWPE 373
              D  PG +G++    + D      +G R E     P      +    P+G +     +
Sbjct: 741 KGEDGFPGFKGDM--GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEK-GK 797

Query: 374 DGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAP 433
            G PG P  PG +GP   +     PG P   GE   R +   A      GQ GP G    
Sbjct: 798 LGVPGLPGYPGRQGP---KGSTGFPGFPGANGEKGARGV---AGKPGPRGQRGPTGPRGS 851

Query: 434 RPLREQLGKIRLELLTIHQAL-----EQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRP- 487
           R  R   GK   +  +          E+  + P  P+     + P  GP       G P 
Sbjct: 852 RGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGP-PGPPGKDGLPGHPG 910

Query: 488 ELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLPLAAPDDPVIPGSGWGT 547
           + G     G   PPG  G   PQ  +G T          PPG     P +  +PG+    
Sbjct: 911 QRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG----PPGEQGLPGAAGKE 966

Query: 548 CVATRSSQTPEAVCGLQSPQG 568
               +    P+ + G   P G
Sbjct: 967 --GAKGDPGPQGISGKDGPAG 985



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 52/183 (28%), Positives = 66/183 (36%), Gaps = 38/183 (20%)

Query: 375 GDPGGPETPGPEGPLPLQP--RGPVPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLA 432
           G  G P   GP GP P  P  RGP PG P   G D               G  GP G + 
Sbjct: 412 GIMGPPGLQGPTGP-PGDPGDRGP-PGRPGLPGAD---------------GLPGPPGTML 454

Query: 433 PRPLREQLGKIRLELLTIHQALEQAV--------RPPDAPLDLSVKRAPAKGPQALGEAW 484
             P R      +   ++  +A  QA+        R P  P+ L+ +  P  GP + G   
Sbjct: 455 MLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKG 514

Query: 485 GRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLPLAAPDD-----PV 539
              + GP        P G+ GP  P    G   +  AD     PG P A  D      P 
Sbjct: 515 ESGDPGP------QGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPG 568

Query: 540 IPG 542
           +PG
Sbjct: 569 LPG 571



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 78/292 (26%), Positives = 100/292 (34%), Gaps = 53/292 (18%)

Query: 283 LAKAPVSPRSPSGTPAPGLLKVPV-PGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSL- 340
           L + P  P  P+G   P  L+ P  P   P  R  P  PG  G         P   L L 
Sbjct: 400 LVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGA--DGLPGPPGTMLMLP 457

Query: 341 ---------GSRLELPKASPSLTRFCSRSSLPTGSSVM-LWPEDGDPGGPET-------- 382
                    G  +   +A        +R +L      M L    G  GGP +        
Sbjct: 458 FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 517

Query: 383 -PGPEGPLPLQ-PRGPV--PGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLRE 438
            PGP+GP  +Q P GP   PG     G D  R +      +   G  G  G    +  R 
Sbjct: 518 DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRG 577

Query: 439 QLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAK-GPQAL-GEAWGRPELGPVLTGG 496
           + G                  PP  P D  ++    + GP+ L GEA  R  LGP  T G
Sbjct: 578 ERGP---------------QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPG 622

Query: 497 TPEPPGMLGPAAPQPFSGHTTKCEADSSVP-------PPGLPLAAPDDPVIP 541
            P  PGM G   P    G+    + +   P       P GLP   P  P+ P
Sbjct: 623 APGQPGMAGVDGPPGPKGNMGP-QGEPGPPGQQGNPGPQGLP--GPQGPIGP 671



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 64/232 (27%), Positives = 81/232 (34%), Gaps = 39/232 (16%)

Query: 90   PDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRAKGSPGPPPPVARATR 149
            P +PG   P  +     P G    P    A+      G   ++ A+G PG   PV     
Sbjct: 1302 PGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGP 1361

Query: 150  KG-PGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCYPPPAPGEFPEAHSL---- 204
             G PGP GL       G  G P   G       GP G  P  PP  PG   +  S     
Sbjct: 1362 AGKPGPEGLRGIPGPVGEQGLPGAAG-----QDGPPG--PMGPPGLPGLKGDPGSKGEKG 1414

Query: 205  HLSLLGVNYPLSPGLFSYLG----------PSLAAAAHVPFLASASPLLPPATAFPAVQP 254
            H  L+G+  P  PG     G          P       +P    A PL PP        P
Sbjct: 1415 HPGLIGLIGP--PGEQGEKGDRGLPGTQGSPGAKGDGGIP--GPAGPLGPPG-------P 1463

Query: 255  PQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPGLLKVPV 306
            P  P P      P   + + G PAG+   +  P  P SP G P   +  +P+
Sbjct: 1464 PGLPGPQG----PKGNKGSTG-PAGQKGDSGLPGPPGSP-GPPGEVIQPLPI 1509


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 122/488 (25%), Positives = 160/488 (32%), Gaps = 113/488 (23%)

Query: 90   PDRPGESDPGRQPQGA----RPTGAAPAPDLVVADIHSLHCGGGPKSRAKGSPGPPPPVA 145
            P  PGE  P + PQG      P G    P     D    H G   ++  +G  GPP P  
Sbjct: 912  PGPPGERGP-QGPQGPVGFPGPKGPPGPPG---KDGLPGHPGQRGETGFQGKTGPPGPGG 967

Query: 146  RATRKGP-GPSGLLPESWKPGMGGDPRGVGA-------GDMASAGPEGSVPCYPPPAPGE 197
                +GP G +G + E   PG  G P   G        G     GP+G      P     
Sbjct: 968  VVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRG 1027

Query: 198  FPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAFPAVQPPQR 257
            FP    L           +PGL    GP          + S        TA P +  P R
Sbjct: 1028 FPGERGLP------GAQGAPGLKGGEGPQGPPGP----VGSPGERGSAGTAGP-IGLPGR 1076

Query: 258  PTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPGLLKVPVPGLGP-WPRVT 316
            P P                P G A    AP   + P G      ++ PV   GP  P  +
Sbjct: 1077 PGPQG--------------PPGPAGEKGAP-GEKGPQGPAGRDGVQGPVGLPGPAGPAGS 1121

Query: 317  PRDPGQEGELERAAQSDPRRRLSLGSRLEL-PKASPSLTRFCSRSSLPTGSSVM------ 369
            P + G +GE+      +P ++ S G + E  P   P L        +  G          
Sbjct: 1122 PGEDGDKGEI-----GEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQ 1176

Query: 370  -LWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQLGPA 428
             ++ + GD G    PGP GP+ LQ    +PG P   GE+     GD       +G +GP 
Sbjct: 1177 GMFGQKGDEGARGFPGPPGPIGLQG---LPGPPGEKGEN-----GD-------VGPMGPP 1221

Query: 429  GGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRPE 488
            G   PR                          P  P      + P   P ++G   G  E
Sbjct: 1222 GPPGPRG-------------------------PQGPNGADGPQGP---PGSVGSVGGVGE 1253

Query: 489  LGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGL--------------PLAA 534
             G     G P PPG  G   P+   G   +     +  PPG               P+  
Sbjct: 1254 KGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGF 1313

Query: 535  PDDPVIPG 542
            P DP  PG
Sbjct: 1314 PGDPGPPG 1321



 Score = 59.3 bits (142), Expect = 9e-09
 Identities = 111/415 (26%), Positives = 142/415 (34%), Gaps = 82/415 (19%)

Query: 134  AKGSPGPPPPVARATRKGP----GPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPC 189
            A+G PGPP P+      GP    G +G +     PG  G PRG   G   + GP+G    
Sbjct: 1187 ARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPG-PRGP-QGPNGADGPQG---- 1240

Query: 190  YPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPF--LASASPLLPPAT 247
             PP + G          S+ GV     PG     GP   A    P           PP  
Sbjct: 1241 -PPGSVG----------SVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEKGEAGPPGA 1289

Query: 248  AFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPGLLKVPVP 307
            A P                                 AK P     P G P P    V  P
Sbjct: 1290 AGPPG-------------------------------AKGPPGDDGPKGNPGP----VGFP 1314

Query: 308  GLGPWPRVTPRDPGQEGEL-ERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPTGS 366
            G  P P   P   GQ+G   ++    DP +    G   E     P   R    ++   G 
Sbjct: 1315 G-DPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEG- 1372

Query: 367  SVMLWPEDGDPGGPETPGPEGPL----PLQPRGPVPGSPEHVG-EDLTRALGDYARVEQR 421
                    G+ G     G EGP     P+ P+GP  G P   G   +   +G+   +   
Sbjct: 1373 ------RQGEKGAKGEAGAEGPPGKTGPVGPQGPA-GKPGPEGLRGIPGPVGEQG-LPGA 1424

Query: 422  LGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAK--GPQA 479
             GQ GP G + P  L    G    +    H  L   + PP    +   +  P     P A
Sbjct: 1425 AGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGA 1484

Query: 480  LGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKC--EADSSVP-PPGLP 531
             G+  G P  GP    G P PPG+ GP  P+   G T     + DS +P PPG P
Sbjct: 1485 KGDG-GIP--GPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSP 1536



 Score = 56.6 bits (135), Expect = 6e-08
 Identities = 120/455 (26%), Positives = 156/455 (34%), Gaps = 74/455 (16%)

Query: 83  PRPHAPT--PDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPK----SRAKG 136
           P    PT  P  PG+  P  +P G       P P   +  +   + G G K    S  + 
Sbjct: 456 PGLQGPTGPPGDPGDRGPPGRP-GLPGADGLPGPPGTMLMLPFRYGGDGSKGPTISAQEA 514

Query: 137 SPGPPPPVARATRKGP-GPSGLLPESWKPGMGGDPRGVGA-GDMASAGPEGSVPCYPPPA 194
                   AR   +GP GP GL   + +PG  G P   GA G+    GP+G      PP 
Sbjct: 515 QAQAILQQARIALRGPPGPMGL---TGRPGPVGGPGSSGAKGESGDPGPQGPRGVQGPPG 571

Query: 195 PGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAFPAVQP 254
           P   P       +  G   P  PG     G                P LP        + 
Sbjct: 572 PTGKPGKRGRPGADGGRGMPGEPGAKGDRG------------FDGLPGLPGDKGHRGERG 619

Query: 255 PQRPTPAPRLYYPLLLEH----TLGLPAGKAALAKAPVSPRSPSGTPA-PGLLKV---PV 306
           PQ P P P     +  E       GLP G+A   +  + PR   G P  PG+  V   P 
Sbjct: 620 PQGP-PGPPGDDGMRGEDGEIGPRGLP-GEAG-PRGLLGPRGTPGAPGQPGMAGVDGPPG 676

Query: 307 PGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLEL-PKASPSLTRFCSRSSLPTG 365
           P     P+  P  PGQ+G      Q  P  +  +G   E  P+  P L      + LP  
Sbjct: 677 PKGNMGPQGEPGPPGQQG--NPGPQGLPGPQGPIGPPGEKGPQGKPGL------AGLPGA 728

Query: 366 SSVMLWPEDGDPGGPETPGPEGPL----PLQPRGPV--PGSPEHVGEDLTRALGDYARVE 419
                   DG PG P   G  G      P  P+GP+  PG     G D  R L      +
Sbjct: 729 --------DGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGEK 780

Query: 420 QRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQA 479
              G  G  G +  +  R ++G+I               R  D P     +  P   P  
Sbjct: 781 GEDGFPGFKGDMGLKGDRGEVGQI-------------GPRGEDGPEGPKGRAGPTGDPGP 827

Query: 480 LGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSG 514
            G+A  + +LG     G P  PG  GP     F G
Sbjct: 828 SGQAGEKGKLG---VPGLPGYPGRQGPKGSTGFPG 859



 Score = 56.2 bits (134), Expect = 8e-08
 Identities = 143/553 (25%), Positives = 177/553 (32%), Gaps = 110/553 (19%)

Query: 79   GSTTP---RPHAPTPDRPGES-------------DPGRQ-------PQGARP-------T 108
            G T P   R H   P  PGE              DPG Q       P G R         
Sbjct: 976  GETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLP 1035

Query: 109  GAAPAPDLVVADIHSLHCGGGPKSRAKGSPGPPPPVARATRKGP-GPSGLLPESWKPGMG 167
            GA  AP L   +      G       +GS G   P+    R GP GP G   E   PG  
Sbjct: 1036 GAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEK 1095

Query: 168  GDPRGVGAGDMASAGPEGSV-PCYPPPAPGEFPEAHSL-------HLSLLGVNYPLSP-G 218
            G P+G  AG     GP G   P  P  +PGE  +   +            G N P  P G
Sbjct: 1096 G-PQGP-AGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPG 1153

Query: 219  LFSYLG-PSLAAAAHVPFLASASPLLPP-----ATAFPAVQPPQRPTPAPRLYYPLLLEH 272
            L   +G P +A     P       +        A  FP   PP           P+ L+ 
Sbjct: 1154 LQGPVGAPGIAGGDGEPGPRGQQGMFGQKGDEGARGFPG--PPG----------PIGLQG 1201

Query: 273  TLGLPAGKAALAKAPVSPRSPSGTPAPGLLKVP---------------VPGLG----PWP 313
              G P  K       V P  P G P P   + P               V G+G    P  
Sbjct: 1202 LPGPPGEKGE--NGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGE 1259

Query: 314  RVTPRDPGQEG-------ELERAAQSDPRRRLSLGSRL----ELPKASPSLTRFCSRSSL 362
               P  PG+ G         E+     P      G++     + PK +P    F      
Sbjct: 1260 AGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGP 1319

Query: 363  P-----TGSSVMLWP--EDGDPGGPETPGPEG----PLPLQPRGPVPGSPEHVGEDLTRA 411
            P      G   +     EDGDPG P  PGP G    P P   RGP PG+    G    + 
Sbjct: 1320 PGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGP-PGAAGAEGRQGEKG 1378

Query: 412  LGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKR 471
                A  E   G+ GP G   P       G   +      Q L  A      P  +    
Sbjct: 1379 AKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPM---- 1434

Query: 472  APAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQ--PFSGHTTKCEADSSVPPPG 529
             P   P   G+   + E G     G   PPG  G    +  P +  +   + D  +P P 
Sbjct: 1435 GPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIPGPA 1494

Query: 530  LPLAAPDDPVIPG 542
             PL  P  P +PG
Sbjct: 1495 GPLGPPGPPGLPG 1507



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 134/531 (25%), Positives = 169/531 (31%), Gaps = 119/531 (22%)

Query: 93   PGESDPGRQPQGARPTGAAPA-PDLVVADIHSLHCGGGPKSRA--KGSPGPPPPVARATR 149
            PGE+ P R   G R T  AP  P +   D        GPK     +G PGPP        
Sbjct: 645  PGEAGP-RGLLGPRGTPGAPGQPGMAGVDGPP-----GPKGNMGPQGEPGPPGQQGNPGP 698

Query: 150  KG-PGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCYPPPAPGEFPEAHSLHLSL 208
            +G PGP G +    + G  G P   G       G +G     PP  PG+  E  S     
Sbjct: 699  QGLPGPQGPIGPPGEKGPQGKPGLAGL-----PGADG-----PPGHPGK--EGQSGEKGA 746

Query: 209  LGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAFPAVQPPQRPTPAPRLYYPL 268
            LG   P  P    Y GP     A        S        FP                  
Sbjct: 747  LGPPGPQGP--IGYPGPRGVKGADGVRGLKGSKGEKGEDGFPG----------------- 787

Query: 269  LLEHTLGLPAGKAALAK-------APVSPRS---PSGTPAPGLL-----KVPVPGLGPWP 313
              +  +GL   +  + +        P  P+    P+G P P        K+ VPGL  +P
Sbjct: 788  -FKGDMGLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEKGKLGVPGLPGYP 846

Query: 314  -RVTPRD-------PGQEGEL-ERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPT 364
             R  P+        PG  GE   R     P  R   G R           R  +    P 
Sbjct: 847  GRQGPKGSTGFPGFPGANGEKGARGVAGKPGPR---GQRGPTGPRGSRGARGPTGKPGPK 903

Query: 365  GSSVMLWPEDGDPGGPETPGPEGPL-------PLQPRGP-----VPGSPEHVGEDLTRAL 412
            G+S      DG PG P   GP+GP        P  P GP     +PG P   GE      
Sbjct: 904  GTS----GGDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGE------ 953

Query: 413  GDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRA 472
                  + + G  GP G + P+    + G I                PP  P +  +  A
Sbjct: 954  ---TGFQGKTGPPGPGGVVGPQGPTGETGPI---------GERGHPGPPGPPGEQGLPGA 1001

Query: 473  PAK-------GPQALGEAWGRP-------ELGPVLTGGTPEPPGMLGPAAPQPFSGHTTK 518
              K       GPQ +    G         E G     G P   G  GP  P    G   +
Sbjct: 1002 AGKEGAKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGE 1061

Query: 519  CEADSSVPPPGLP-LAAPDDPVIPGSGWGTCVATRSSQTPEAVCGLQSPQG 568
              +  +  P GLP    P  P  P    G     +  Q P    G+Q P G
Sbjct: 1062 RGSAGTAGPIGLPGRPGPQGPPGPAGEKG-APGEKGPQGPAGRDGVQGPVG 1111



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 126/501 (25%), Positives = 164/501 (32%), Gaps = 79/501 (15%)

Query: 127  GGGPKSRAKGSPGPPPPVA-RATRKGPGPSGLLPESWKP------GMGGDPRGVG----- 174
            GG   S AKG  G P P   R  +  PGP+G   +  +P      GM G+P   G     
Sbjct: 544  GGPGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFD 603

Query: 175  -----AGDMASAGPEGSVPCYPPPAPG-EFPEAHSLHLSLLGVNYPLSPGLFSYLGP-SL 227
                  GD    G  G  P  PP  PG +        +   G+  P   G    LGP   
Sbjct: 604  GLPGLPGDKGHRGERG--PQGPPGPPGDDGMRGEDGEIGPRGL--PGEAGPRGLLGPRGT 659

Query: 228  AAAAHVPFLASA-SPLLPPATAFPAVQP----------------PQRPTPAPRLYYPLLL 270
              A   P +A    P  P     P  +P                PQ P   P    P   
Sbjct: 660  PGAPGQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGK 719

Query: 271  EHTLGLPA--------GKAAL-----AKAPVSPRSPSGTPAPGLLKVP--VPGLGPWPRV 315
                GLP         GK        A  P  P+ P G P P  +K    V GL      
Sbjct: 720  PGLAGLPGADGPPGHPGKEGQSGEKGALGPPGPQGPIGYPGPRGVKGADGVRGLKGSKGE 779

Query: 316  TPRD--PGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVMLWPE 373
               D  PG +G++    + D      +G R E     P      +    P+G +     +
Sbjct: 780  KGEDGFPGFKGDM--GLKGDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQAGEK-GK 836

Query: 374  DGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAP 433
             G PG P  PG +GP   +     PG P   GE   R +   A      GQ GP G    
Sbjct: 837  LGVPGLPGYPGRQGP---KGSTGFPGFPGANGEKGARGV---AGKPGPRGQRGPTGPRGS 890

Query: 434  RPLREQLGKIRLELLTIHQAL-----EQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRP- 487
            R  R   GK   +  +          E+  + P  P+     + P  GP       G P 
Sbjct: 891  RGARGPTGKPGPKGTSGGDGPPGPPGERGPQGPQGPVGFPGPKGP-PGPPGKDGLPGHPG 949

Query: 488  ELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLPLAAPDDPVIPGSGWGT 547
            + G     G   PPG  G   PQ  +G T          PPG     P +  +PG+    
Sbjct: 950  QRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPG----PPGEQGLPGAAGKE 1005

Query: 548  CVATRSSQTPEAVCGLQSPQG 568
                +    P+ + G   P G
Sbjct: 1006 --GAKGDPGPQGISGKDGPAG 1024



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 52/183 (28%), Positives = 66/183 (36%), Gaps = 38/183 (20%)

Query: 375 GDPGGPETPGPEGPLPLQP--RGPVPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLA 432
           G  G P   GP GP P  P  RGP PG P   G D               G  GP G + 
Sbjct: 451 GIMGPPGLQGPTGP-PGDPGDRGP-PGRPGLPGAD---------------GLPGPPGTML 493

Query: 433 PRPLREQLGKIRLELLTIHQALEQAV--------RPPDAPLDLSVKRAPAKGPQALGEAW 484
             P R      +   ++  +A  QA+        R P  P+ L+ +  P  GP + G   
Sbjct: 494 MLPFRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKG 553

Query: 485 GRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLPLAAPDD-----PV 539
              + GP        P G+ GP  P    G   +  AD     PG P A  D      P 
Sbjct: 554 ESGDPGP------QGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPG 607

Query: 540 IPG 542
           +PG
Sbjct: 608 LPG 610



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 78/292 (26%), Positives = 100/292 (34%), Gaps = 53/292 (18%)

Query: 283 LAKAPVSPRSPSGTPAPGLLKVPV-PGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSL- 340
           L + P  P  P+G   P  L+ P  P   P  R  P  PG  G         P   L L 
Sbjct: 439 LVEGPPGPAGPAGIMGPPGLQGPTGPPGDPGDRGPPGRPGLPGA--DGLPGPPGTMLMLP 496

Query: 341 ---------GSRLELPKASPSLTRFCSRSSLPTGSSVM-LWPEDGDPGGPET-------- 382
                    G  +   +A        +R +L      M L    G  GGP +        
Sbjct: 497 FRYGGDGSKGPTISAQEAQAQAILQQARIALRGPPGPMGLTGRPGPVGGPGSSGAKGESG 556

Query: 383 -PGPEGPLPLQ-PRGPV--PGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLRE 438
            PGP+GP  +Q P GP   PG     G D  R +      +   G  G  G    +  R 
Sbjct: 557 DPGPQGPRGVQGPPGPTGKPGKRGRPGADGGRGMPGEPGAKGDRGFDGLPGLPGDKGHRG 616

Query: 439 QLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAK-GPQAL-GEAWGRPELGPVLTGG 496
           + G                  PP  P D  ++    + GP+ L GEA  R  LGP  T G
Sbjct: 617 ERGP---------------QGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPG 661

Query: 497 TPEPPGMLGPAAPQPFSGHTTKCEADSSVP-------PPGLPLAAPDDPVIP 541
            P  PGM G   P    G+    + +   P       P GLP   P  P+ P
Sbjct: 662 APGQPGMAGVDGPPGPKGNMGP-QGEPGPPGQQGNPGPQGLP--GPQGPIGP 710



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 64/232 (27%), Positives = 81/232 (34%), Gaps = 39/232 (16%)

Query: 90   PDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRAKGSPGPPPPVARATR 149
            P +PG   P  +     P G    P    A+      G   ++ A+G PG   PV     
Sbjct: 1341 PGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGP 1400

Query: 150  KG-PGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCYPPPAPGEFPEAHSL---- 204
             G PGP GL       G  G P   G       GP G  P  PP  PG   +  S     
Sbjct: 1401 AGKPGPEGLRGIPGPVGEQGLPGAAG-----QDGPPG--PMGPPGLPGLKGDPGSKGEKG 1453

Query: 205  HLSLLGVNYPLSPGLFSYLG----------PSLAAAAHVPFLASASPLLPPATAFPAVQP 254
            H  L+G+  P  PG     G          P       +P    A PL PP        P
Sbjct: 1454 HPGLIGLIGP--PGEQGEKGDRGLPGTQGSPGAKGDGGIP--GPAGPLGPPG-------P 1502

Query: 255  PQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPGLLKVPV 306
            P  P P      P   + + G PAG+   +  P  P SP G P   +  +P+
Sbjct: 1503 PGLPGPQG----PKGNKGSTG-PAGQKGDSGLPGPPGSP-GPPGEVIQPLPI 1548


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 108/376 (28%), Positives = 130/376 (34%), Gaps = 60/376 (15%)

Query: 78   RGSTTPRPHAP----TPDRPG-ESDPG-RQPQGARPTGAAPAPDLVVADIHSLHCGGGPK 131
            R      P AP    +P  PG   DPG R P+G  P G   AP  V+        G GP 
Sbjct: 1312 RAGNPGTPGAPGLKGSPGLPGPRGDPGERGPRG--PKGEPGAPGQVIG-------GEGPG 1362

Query: 132  SRA-KGSPGPPPPVARATRKGPGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCY 190
                KG PGP  P        PGP G L +    G  G P     GD    G  G     
Sbjct: 1363 LPGRKGDPGPSGP--------PGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERG----- 1409

Query: 191  PPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAFP 250
             PP PGE   A      L G+  P SPG    +GP              +P LP     P
Sbjct: 1410 -PPGPGEGGIAPG-EPGLPGL--PGSPGPQGPVGPP-GKKGEKGDSEDGAPGLPGQPGSP 1464

Query: 251  AVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPA----PGLLKVPV 306
              Q P+ P  A            LG    K    + P  P    G P     PG  K P 
Sbjct: 1465 GEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGE--RGPPGPAGSRGLPGVAGRPGA-KGPE 1521

Query: 307  PGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPTGS 366
               GP  R      G++GE  R            G + E     P+  R  +      G 
Sbjct: 1522 GPPGPTGR-----QGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGP 1576

Query: 367  SVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQLG 426
              ++ P  GDPG    PG  GP+ L  R   PG     GE      GD        G+ G
Sbjct: 1577 PGLVLP--GDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEK-----GD-------PGRPG 1622

Query: 427  PAGGLAPRPLREQLGK 442
            P G + PR    ++G+
Sbjct: 1623 PPGPVGPRGRDGEVGE 1638



 Score = 59.3 bits (142), Expect = 9e-09
 Identities = 113/429 (26%), Positives = 142/429 (33%), Gaps = 91/429 (21%)

Query: 136  GSPGPPPPVARATRKG-------------PGPSGLLPESWKPGMGGDPRGVGA-GDMASA 181
            G+PGP  P   AT KG             PG +G       PG+ G P   G  GD    
Sbjct: 1281 GAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGSPGLPGPRGDPGER 1340

Query: 182  GPEGSVPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASP 241
            GP G  P   P APG+          ++G   P  PG     GPS       P L    P
Sbjct: 1341 GPRG--PKGEPGAPGQ----------VIGGEGPGLPGRKGDPGPSGPPGPRGP-LGDPGP 1387

Query: 242  LLPPATAFPAVQPP-----QRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSP--RSPS 294
              PP     A++       +R  P P            G+  G+  L   P SP  + P 
Sbjct: 1388 RGPPGLPGTAMKGDKGDRGERGPPGPG---------EGGIAPGEPGLPGLPGSPGPQGPV 1438

Query: 295  GTPAPGLLKVPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLS----LGSRLELPKAS 350
            G P     K       P     P  PG++G         P+        LG   E  +  
Sbjct: 1439 GPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGPKGDRGFPGPLGEAGEKGERG 1498

Query: 351  PSLTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPL-PLQPRGPV-----PGSPEHV 404
            P           P GS  +     G  G P   GPEGP  P   +G       PG P  V
Sbjct: 1499 PPG---------PAGSRGL----PGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVV 1545

Query: 405  GEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAP 464
            G  +    G+        G +GPAG      ++ + G   L L                P
Sbjct: 1546 GPAVAGPKGEK-------GDVGPAGPRGATGVQGERGPPGLVL----------------P 1582

Query: 465  LDLSVKRAPA-KGPQALGEAWGRP-ELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEAD 522
             D   K  P  +GP  L    G P + GP    G P  PG  GP  P+   G   +   +
Sbjct: 1583 GDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDE 1642

Query: 523  SSVPPPGLP 531
                 PGLP
Sbjct: 1643 GPPGDPGLP 1651



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 126/470 (26%), Positives = 164/470 (34%), Gaps = 81/470 (17%)

Query: 74   WACRRGSTTPRPH---APTPDRPGESDPGRQ-------PQGARPTGAAPAPDLVVADIHS 123
            W    GS  P P     P  D   +  PG++        +G +     P P         
Sbjct: 1963 WDESSGSFLPVPERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGDRGDPGPQ-------- 2014

Query: 124  LHCGGGPKSRAKGSPGPPPPVARATRKG-------PGPSGLLPESWKPGMGGDPRGVG-A 175
                 GP   A G  GPP P   A   G       PG +G + E+ +PG  G+    G  
Sbjct: 2015 -----GPPGLALGERGPPGPSGLAGEPGKPGIPGLPGRAGGVGEAGRPGERGERGEKGER 2069

Query: 176  GDMASAGPEGSVPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLG-PSLAAAAHVP 234
            G+    GP G +P  P P     P+        + V+ P  PGL    G P L  A   P
Sbjct: 2070 GEQGRDGPPG-LPGTPGPPGPPGPK--------VSVDEP-GPGLSGEQGPPGLKGAKGEP 2119

Query: 235  FLASASPLLPPATAFPAVQPPQRPTPAPRLY---YPLLLEHTLGLPAGKAAL--AKAPVS 289
               S     P            R  P PR       L  E  +  P GK  L   + P  
Sbjct: 2120 --GSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPEGKPGLQGPRGPPG 2177

Query: 290  PRSPSGTPA-PGLLKVPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSL-----GSR 343
            P    G P  PG   +  P     P     +PG+ G   R   + P   + L      S 
Sbjct: 2178 PVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPGETGPPGRGL-TGPTGAVGLPGPPGPSG 2236

Query: 344  LELPKASPSLTRFCSRSSLP-----TGSSVMLWPEDGDPGGPETPGPEG-PLPLQPRGPV 397
            L  P+ SP L      +  P      G+S     +DGD G P  PG  G P P+ P+G  
Sbjct: 2237 LVGPQGSPGLPGQVGETGKPGAPGRDGAS----GKDGDRGSPGVPGSPGLPGPVGPKGE- 2291

Query: 398  PGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQA 457
            PG     G+ +    G         G+ G  GGLA   + E   K    L        +A
Sbjct: 2292 PGPTGAPGQAVVGLPG-------AKGEKGAPGGLAGDLVGEPGAKGDRGLPGPRGEKGEA 2344

Query: 458  VR--PPDAPLDLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEPPGMLG 505
             R   P  P +   K AP  GP+      G P +G   + G P PPG+ G
Sbjct: 2345 GRAGEPGDPGEDGQKGAP--GPKGFK---GDPGVGVPGSPGPPGPPGVKG 2389



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 133/510 (26%), Positives = 156/510 (30%), Gaps = 109/510 (21%)

Query: 83   PRPHAPT--PDRPGESD-PGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRAKGSPG 139
            P P  P   P +PGE   PG   +   P            D      G    S  +G  G
Sbjct: 1820 PGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGE-------DGRKGEKGDSGASGREGRDG 1872

Query: 140  PPPPVARATRKGP-GPSGLLPESWKPGMG--GDPRGVGA-GDMASAGPEGSVPCYPPPA- 194
            P          GP GP GL      PG G  G P G G  GD    G +G          
Sbjct: 1873 PKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGL 1932

Query: 195  ---PGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFL-----ASASPLLPPA 246
               PG  P    L L   G+       +      S  +   VP         +    PP 
Sbjct: 1933 RGEPGSVPNVDRL-LETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSGEQGPPG 1991

Query: 247  TAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPA-PGLLKVP 305
               P   P +R     R           G P G   LA     P  PSG    PG  K  
Sbjct: 1992 KEGPIGFPGERGLKGDR--------GDPG-PQGPPGLALGERGPPGPSGLAGEPG--KPG 2040

Query: 306  VPGLGPWPRVTPRDPGQEGELERAAQSDPR-RRLSLGSRLELPKASPSLTRFCSRSSLPT 364
            +PGL          PG+ G +  A +   R  R   G R E  +                
Sbjct: 2041 IPGL----------PGRAGGVGEAGRPGERGERGEKGERGEQGR---------------- 2074

Query: 365  GSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQ 424
                     DG PG P TPGP GP   +     PG P   GE     L          G 
Sbjct: 2075 ---------DGPPGLPGTPGPPGPPGPKVSVDEPG-PGLSGEQGPPGLKGAKGEPGSNGD 2124

Query: 425  LGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQALGEAW 484
             GP G      ++   G             E   R  D    L  +R  A GP+      
Sbjct: 2125 QGPKGDRGVPGIKGDRG-------------EPGPRGQDGNPGLPGERGMA-GPEGKPGLQ 2170

Query: 485  G-RPELGPVLTGGTPEP---PGMLGPAAPQPFSGHTTKCEADSSVPPPGLPLAAPDDPV- 539
            G R   GPV   G P P   PG+ GPA PQ  SG   +        PPG  L  P   V 
Sbjct: 2171 GPRGPPGPVGGHGDPGPPGAPGLAGPAGPQGPSGLKGE---PGETGPPGRGLTGPTGAVG 2227

Query: 540  IPGSGWGTCVATRSSQTPEAVCGLQSPQGA 569
            +PG              P    GL  PQG+
Sbjct: 2228 LPG--------------PPGPSGLVGPQGS 2243



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 130/512 (25%), Positives = 162/512 (31%), Gaps = 118/512 (23%)

Query: 78   RGSTTPRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRAKGS 137
            RG   PR     P  PGE      P+G +P    P                GP     G 
Sbjct: 2140 RGEPGPRGQDGNPGLPGERGMAG-PEG-KPGLQGPR---------------GPPGPVGGH 2182

Query: 138  PGPPPPVARATRKGPGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCYPPPAPGE 197
              P PP A       GP G        G+ G+P   G       GP G+V    PP P  
Sbjct: 2183 GDPGPPGAPGLAGPAGPQG------PSGLKGEPGETGPPGRGLTGPTGAVGLPGPPGPS- 2235

Query: 198  FPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLAS------ASPLLPPATAFPA 251
                      L+G     SPGL   +G +    A     AS       SP +P +   P 
Sbjct: 2236 ---------GLVGPQG--SPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPG 2284

Query: 252  VQPPQ---RPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPGLLK---VP 305
               P+    PT AP        +  +GLP  K                 APG L    V 
Sbjct: 2285 PVGPKGEPGPTGAPG-------QAVVGLPGAKGEKG-------------APGGLAGDLVG 2324

Query: 306  VPGLGPWPRVTPRDPGQEGELERAAQ-SDPRRRLSLGSRLELPKASPSLTRFCSRSSLPT 364
             PG     R  P   G++GE  RA +  DP          +  K +P    F        
Sbjct: 2325 EPG-AKGDRGLPGPRGEKGEAGRAGEPGDPGE--------DGQKGAPGPKGFKGD----- 2370

Query: 365  GSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVG-EDLTRALGDYARVEQRLG 423
                   P  G PG P  PGP G         +PG+P  VG    T   G+       +G
Sbjct: 2371 -------PGVGVPGSPGPPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGE-------MG 2416

Query: 424  QLGPAG--GLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPA----KGP 477
            Q GP+G  GLA  P RE               +   + PP  P  +    A      KG 
Sbjct: 2417 QPGPSGERGLAGPPGRE--------------GIPGPLGPPGPPGSVGPPGASGLKGDKGD 2462

Query: 478  QALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLPLAAPDD 537
              +G    R E G     G    PG  GP       G   +      V   GL     D 
Sbjct: 2463 PGVGLPGPRGERGEPGIRGEDGRPGQEGPRGLTGPPGSRGERGEKGDVGSAGLKGDKGDS 2522

Query: 538  PVIPG-SGWGTCVATRSSQTPEAVCGLQSPQG 568
             VI G  G          + P  + G + P+G
Sbjct: 2523 AVILGPPGPRGAKGDMGERGPRGLDGDKGPRG 2554



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 125/484 (25%), Positives = 147/484 (30%), Gaps = 136/484 (28%)

Query: 90   PDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRA--KGSPGPPPPVA-- 145
            P  PGE  P   P    P G    P              GP   A  KG  GPP P    
Sbjct: 1461 PGSPGEQGPRGPPGAIGPKGDRGFP--------------GPLGEAGEKGERGPPGPAGSR 1506

Query: 146  -------RATRKGP----GPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSV-PCYPPP 193
                   R   KGP    GP+G   E  +PG  GDP  VG       G +G V P  P  
Sbjct: 1507 GLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAVAGPKGEKGDVGPAGPRG 1566

Query: 194  APGEFPEAHSLHLSLLGVNYPLS-PGLFSYLGPSLAAAAHVPFLASASPLLPPATAFPAV 252
            A G   E     L L G   P   PG    +G +  A              PP  + P  
Sbjct: 1567 ATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAG-------------PPGDSGPPG 1613

Query: 253  QPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPGLLKVPVPG-LGP 311
            +      P P                        PV PR   G       +V   G  GP
Sbjct: 1614 EKGDPGRPGP----------------------PGPVGPRGRDG-------EVGEKGDEGP 1644

Query: 312  WPRVTPRDPGQEGEL-ERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVML 370
                 P DPG  G+  ER  +  P  R  +G + +             R+  P  S    
Sbjct: 1645 -----PGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPGED-----GRNGSPGSSG--- 1691

Query: 371  WPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGG 430
                GD G P  PGP G L        PG+ E  GE   R            GQ GP G 
Sbjct: 1692 --PKGDRGEPGPPGPPGRLV----DTGPGAREK-GEPGDR------------GQEGPRGP 1732

Query: 431  LAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRPELG 490
                 L    G+  +E            R P  P      R PA      GE   R   G
Sbjct: 1733 KGDPGLPGAPGERGIE----------GFRGPPGPQGDPGVRGPA------GEKGDRGPPG 1776

Query: 491  PVLTGGTPEPPGMLGPAAPQPFSGHT--------TKCEADSSVP----PPGLPLAAPDDP 538
                 G    PG  GP+ P   +G               +  +P    PPGLP   P + 
Sbjct: 1777 LDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLP-GKPGED 1835

Query: 539  VIPG 542
              PG
Sbjct: 1836 GKPG 1839



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 119/482 (24%), Positives = 144/482 (29%), Gaps = 123/482 (25%)

Query: 83   PRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRAKGSPGPPP 142
            P    P  ++  + DPG   +   P  + P  D                   +G PGPP 
Sbjct: 1663 PGVRGPVGEKGDQGDPGEDGRNGSPGSSGPKGD-------------------RGEPGPPG 1703

Query: 143  PVARATRKGPGPSGLLPESWKPGMGGD--PRGV--GAGDMASAGPEGSVPCYPPPAPGEF 198
            P  R    GPG      E  +PG  G   PRG     G   + G  G      PP P   
Sbjct: 1704 PPGRLVDTGPGAR----EKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEGFRGPPGPQGD 1759

Query: 199  PEAHSLHLSLLGVNYPLS-------PGLFSYLGPSLAAAAHVPFLASASPLLPPATAFPA 251
            P          GV  P         PGL    G      A       A P  P   A  A
Sbjct: 1760 P----------GVRGPAGEKGDRGPPGLDGRSGLDGKPGA-------AGPSGPNGAAGKA 1802

Query: 252  VQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPA-PGLLKVPVPGLG 310
              P +   P         L    GLP            P  P G P  PG  +   PGL 
Sbjct: 1803 GDPGRDGLPG--------LRGEQGLP-----------GPSGPPGLPGKPG--EDGKPGLN 1841

Query: 311  PWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVML 370
                  P DPG++G       S    R       + PK                G+  +L
Sbjct: 1842 -GKNGEPGDPGEDGRKGEKGDSGASGR----EGRDGPKGE-------------RGAPGIL 1883

Query: 371  WPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGG 430
             P+    G P  PGP GP    P    PG P   G    R            G  G  G 
Sbjct: 1884 GPQ----GPPGLPGPVGP----PGQGFPGVPGGTGPKGDRG---------ETGSKGEQGL 1926

Query: 431  LAPRPLREQLGKI-----RLELLTIH-QALEQAVRPPDAP----LDLSVKRAPAKGPQAL 480
               R LR + G +      LE   I   AL + V   D      L +  +R   KG    
Sbjct: 1927 PGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDS-- 1984

Query: 481  GEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLPLAAPDDPVI 540
            GE     + GP+   G P   G+ G        G       +   P P      P  P I
Sbjct: 1985 GEQGPPGKEGPI---GFPGERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGI 2041

Query: 541  PG 542
            PG
Sbjct: 2042 PG 2043



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 118/499 (23%), Positives = 153/499 (30%), Gaps = 81/499 (16%)

Query: 68   LLDSPDWACRRGSTTPRPHAPTPDRPGE-SDPGRQPQGARPTGAAPAPDLVVADIHSLHC 126
            L+  P     RG   PR       R GE  DPG   Q       AP P     D      
Sbjct: 2322 LVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKG-----APGPKGFKGD------ 2370

Query: 127  GGGPKSRAKGSPGPPPPVARATRKGPGPSGLLPESWKPGMGGDPRGVG-------AGDMA 179
               P     GSPGPP           GP G+  +   PG+ G P  VG        G+M 
Sbjct: 2371 ---PGVGVPGSPGPP-----------GPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMG 2416

Query: 180  SAGPEGSVPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLG-PSLAAAAHVPFLAS 238
              GP G      PP     P           V  P + GL    G P +      P    
Sbjct: 2417 QPGPSGERGLAGPPGREGIPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPG--PRGER 2474

Query: 239  ASPLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPA 298
              P +      P  + P+  T  P        E       G A L           G P 
Sbjct: 2475 GEPGIRGEDGRPGQEGPRGLTGPPGSRG----ERGEKGDVGSAGLKGDKGDSAVILGPPG 2530

Query: 299  PGLLKVPVPGLGP-------WPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASP 351
            P   K  +   GP        PR    DPG +G     ++ +P  + S G         P
Sbjct: 2531 PRGAKGDMGERGPRGLDGDKGPRGDNGDPGDKG-----SKGEPGDKGSAG--------LP 2577

Query: 352  SLTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRA 411
             L         P  + +      GDPG P   G  G    +      G     GE   + 
Sbjct: 2578 GLRGLLGPQGQPGAAGI-----PGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKG 2632

Query: 412  LGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKR 471
                   +   G+ GP G       + ++G+  +   +     E  + P     D     
Sbjct: 2633 ACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKG---DRGFDG 2689

Query: 472  APA-KGPQALGEAWGRPELG--PVLTG-----GTPEPPGMLGPAAPQPFSGHTTKCEADS 523
             P  KG Q      G P +G  P  +G     G P PPG +GP  P+   G     +   
Sbjct: 2690 QPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQG-----QKGE 2744

Query: 524  SVPPPGLPLAAPDDPVIPG 542
              PP    + AP  P  PG
Sbjct: 2745 RGPPGERVVGAPGVPGAPG 2763



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 115/446 (25%), Positives = 145/446 (32%), Gaps = 131/446 (29%)

Query: 79   GSTTPRPHAPTPDRPGE----SDPGRQ-------PQGARPTGAAPAPDLVVADIHSLHCG 127
            G T PR     P   GE      PGR+       P G  P G+   P            G
Sbjct: 2407 GQTGPRGEMGQPGPSGERGLAGPPGREGIPGPLGPPG--PPGSVGPP------------G 2452

Query: 128  GGPKSRAKGSPGPPPPVARATRKGPGPSGLLPESWKPGMGGDPRGVGA-----------G 176
                   KG PG   P  R  R  PG  G   E  +PG  G PRG+             G
Sbjct: 2453 ASGLKGDKGDPGVGLPGPRGERGEPGIRG---EDGRPGQEG-PRGLTGPPGSRGERGEKG 2508

Query: 177  DMASAGPEG----SVPCYPPPAP----GEFPEAHSLHLSLLGVNYPLS------------ 216
            D+ SAG +G    S     PP P    G+  E     L   G   P              
Sbjct: 2509 DVGSAGLKGDKGDSAVILGPPGPRGAKGDMGERGPRGLD--GDKGPRGDNGDPGDKGSKG 2566

Query: 217  ----------PGLFSYLGPS-LAAAAHVPFLASASPLLPPATAFPAVQPPQRPTP--APR 263
                      PGL   LGP     AA +P      P  P     P ++  +       PR
Sbjct: 2567 EPGDKGSAGLPGLRGLLGPQGQPGAAGIP----GDPGSPGKDGVPGIRGEKGDVGFMGPR 2622

Query: 264  -LYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPGLLKVP-VPGLGPWPRVTPRDPG 321
             L     ++   GL   K    +A   P  P      G +  P VPG           PG
Sbjct: 2623 GLKGERGVKGACGLDGEKGDKGEAG-PPGRPGLAGHKGEMGEPGVPGQSG-------APG 2674

Query: 322  QEGEL----ERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVMLWPEDGDP 377
            +EG +    +R     P  +   G + E  + +P +  F      P+G+        G P
Sbjct: 2675 KEGLIGPKGDRGFDGQPGPKGDQGEKGE--RGTPGIGGFPG----PSGND----GSAGPP 2724

Query: 378  GGPETPGPEGPLPLQ----PRGP----------VPGSPEHVGEDLTRALGDYARVEQRLG 423
            G P + GP GP  LQ     RGP          VPG+P   GE            + R G
Sbjct: 2725 GPPGSVGPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGE------------QGRPG 2772

Query: 424  QLGPAGGLAPRPLREQ--LGKIRLEL 447
              GP G      L E    G +R E+
Sbjct: 2773 PAGPRGEKGEAALTEDDIRGFVRQEM 2798



 Score = 30.4 bits (67), Expect = 4.6
 Identities = 52/196 (26%), Positives = 66/196 (33%), Gaps = 27/196 (13%)

Query: 356  FCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDY 415
            +C +        + L  + G PG P  PG  G     P+GP PGS    GE        +
Sbjct: 1250 YCPKGQKGEPGEMGLRGQVGPPGDPGLPGRTGAPG--PQGP-PGSATAKGER------GF 1300

Query: 416  ARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAK 475
               + R G  G AG           G   L         +   R P  P     K  P  
Sbjct: 1301 PGADGRPGSPGRAGNPGTPGAPGLKGSPGLP----GPRGDPGERGPRGP-----KGEPGA 1351

Query: 476  GPQAL-GEAWGRP----ELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCE----ADSSVP 526
              Q + GE  G P    + GP    G   P G  GP  P    G   K +     +   P
Sbjct: 1352 PGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLPGTAMKGDKGDRGERGPP 1411

Query: 527  PPGLPLAAPDDPVIPG 542
             PG    AP +P +PG
Sbjct: 1412 GPGEGGIAPGEPGLPG 1427


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 62.0 bits (149), Expect = 1e-09
 Identities = 90/355 (25%), Positives = 115/355 (32%), Gaps = 79/355 (22%)

Query: 62  KDSLSLLLDSPDWACRRGSTTPRPHAPTPDRPGESDP--GRQPQGARPTGAAPAPDLVVA 119
           ++S SL+  +P     +G   P+   P P +P    P  G +PQG  P G    P     
Sbjct: 26  EESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP---- 81

Query: 120 DIHSLHCGGGPKSRAK----GSPGPPPPVARATRKGPGPSGLLPESWKPGMGGDPRG-VG 174
                    G KSR+     G P  PPP      +GP P    P+   P  G  P+G   
Sbjct: 82  -------PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPP 134

Query: 175 AGDMASAGPEGSVPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVP 234
            G      P+G     P   PG+ P+         G N P  P       P        P
Sbjct: 135 PGKPQGPPPQGDKSRSPRSPPGK-PQGPPPQ----GGNQPQGP------PPPPGKPQGPP 183

Query: 235 FLASASPLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPS 294
                 P  PP    P   PPQ          P       G P G       P     P 
Sbjct: 184 PQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPP-------GKPQG-----PPPQGGNQPQ 231

Query: 295 G-TPAPGLLKVPVPGLGPWPRVTP------RDPGQEGELERAAQSDPRRRLSLGSRLELP 347
           G  P PG  + P P  G  P+  P        P Q G   ++A+S P +          P
Sbjct: 232 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGK----------P 281

Query: 348 KASPSLTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPE 402
           +  P                     E  +P GP  P P G  P QP+ P  G P+
Sbjct: 282 QGPPQ-------------------QEGNNPQGP--PPPAGGNPQQPQAPPAGQPQ 315



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 64/254 (25%), Positives = 84/254 (33%), Gaps = 45/254 (17%)

Query: 287 PVSPRSPSGTPAPGLLKVPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSL----GS 342
           P  P  P G P  G  K      GP P   P+ P  +G+  R+ +S P +        G+
Sbjct: 51  PPPPGKPQGPPPQGGNKPQ----GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGN 106

Query: 343 RLELPKASPSLTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPE 402
           + + P   P   +         G+     P  G P GP   G +   P  P G   G P 
Sbjct: 107 QPQGPPPPPGKPQGPPPQG---GNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPP 163

Query: 403 HVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPD 462
             G              Q  G   P G   P+    Q GK             Q   PP 
Sbjct: 164 QGG-------------NQPQGPPPPPG--KPQGPPPQGGK-----------KPQGPPPPG 197

Query: 463 APLDLSVKRAPAKGPQA-LGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEA 521
            P     +   ++  Q+  G+  G P  G     G P PPG   P  P P  G+  +   
Sbjct: 198 KPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGK--PQGPPPQGGNKPQ--- 252

Query: 522 DSSVPPPGLPLAAP 535
               PPPG P   P
Sbjct: 253 --GPPPPGKPQGPP 264



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 51/194 (26%), Positives = 62/194 (31%), Gaps = 48/194 (24%)

Query: 78  RGSTTPRPHAPTPDRPGESDP--GRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRAK 135
           +G   P+   P P +P    P  G++PQG  P G    P              G KSR+ 
Sbjct: 164 QGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPP-----------PQGDKSRSS 212

Query: 136 ----GSPGPPPPVARATRKGP-----GPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGS 186
               G P  PPP      +GP      P G  P+      G  P G   G  A  G +  
Sbjct: 213 QSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQ 272

Query: 187 VPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPA 246
               PP  P   P+           N P  P                P  A  +P  P A
Sbjct: 273 SARSPPGKPQGPPQQEG--------NNPQGP----------------PPPAGGNPQQPQA 308

Query: 247 TAFPAVQPPQRPTP 260
              PA QP   P P
Sbjct: 309 P--PAGQPQGPPRP 320



 Score = 30.4 bits (67), Expect = 4.6
 Identities = 28/120 (23%), Positives = 39/120 (32%), Gaps = 10/120 (8%)

Query: 78  RGSTTP--RPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRAK 135
           R S +P  +P  P P + G    G  P   +P G  P          +   G  P  + +
Sbjct: 210 RSSQSPPGKPQGPPP-QGGNQPQGPPPPPGKPQGPPPQGG-------NKPQGPPPPGKPQ 261

Query: 136 GSPGPPPPVARATRKGPGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCYPPPAP 195
           G P      +++ R  PG     P+       G P   G        P    P  PP  P
Sbjct: 262 GPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPP 321


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 121/511 (23%), Positives = 167/511 (32%), Gaps = 64/511 (12%)

Query: 71  SPDWACRRGSTTPRPHAPTPDRPGESDPGRQPQGARPTGAAPA----PDL-VVADIHSLH 125
           SP  A       P P AP   +   S P   P  A P+   P     P L  +  I   H
Sbjct: 334 SPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPH 393

Query: 126 CGGGPKSRAKGSPGPPPPVA----RATRKGPGPSGLLPESWKPGMGGDPRGVGAGDMASA 181
               P  +A     PP P+A    +AT     P+     S+   +   PR   A   + +
Sbjct: 394 SLTSPSLQA-----PPSPLALSSLQATTSLGSPTLQATHSF---LTMSPRQTQASLTSPS 445

Query: 182 GPEGSVPCYPP-PAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAA-AAHVPFLASA 239
            P  + P  PP  AP   P +  L  SL     PLS  L  +   +L++ A+H P    +
Sbjct: 446 RPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLS 505

Query: 240 SPLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAP 299
           S ++PP     ++ PP   TP   L  P  LE+   L       A AP++       P P
Sbjct: 506 SLIMPPLETQSSLAPPSLQTPPASLTTP-PLENLPSLAPPPLQTASAPLTTPHLETPPCP 564

Query: 300 GLLKVPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSR 359
               +  P   P P  TP             Q+ P         L  P  SP  T     
Sbjct: 565 APCPLQAP---PSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLAT----- 616

Query: 360 SSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVE 419
              P     +  P    P  P    P  PL      P P +P  +   L +A        
Sbjct: 617 -PPPQAPPXLALPPLQAPPSPPASPPLSPLAT----PSPQAPNALAVHLLQAPFSPPPSP 671

Query: 420 QRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVK--RAPAKGP 477
                  P       P                     A  P  AP  L+    + P   P
Sbjct: 672 PVQAPFSPPASPPVSP--------------------SATPPSQAPPSLAAPPLQVPPSPP 711

Query: 478 QALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLP--LAAP 535
            +       P + P  T     PP +  P    P S   +   + S+ PPP +P  LAAP
Sbjct: 712 AS-------PPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAP 764

Query: 536 DDPVIPGSGWGTCVATRSSQTPEAVCGLQSP 566
              V P       ++  +   P+A   L +P
Sbjct: 765 PLQVPPSPPASLPMSPLAKPPPQAPPALATP 795



 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 111/472 (23%), Positives = 157/472 (33%), Gaps = 81/472 (17%)

Query: 82  TPRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRAKGSPGPP 141
           TP     TP  P E+ P   P    P   A AP L    + +  C      +A  SP   
Sbjct: 525 TPPASLTTP--PLENLPSLAPP---PLQTASAP-LTTPHLETPPCPAPCPLQAPPSPLTT 578

Query: 142 PPVARATRKGPGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCYPPPAPGEFPEA 201
           PP    +     P    P    P + G P          + P   +   PP AP      
Sbjct: 579 PPPETPSSIATPPPQAPPALASPPLQGLP----------SPPLSPLATPPPQAPPX---- 624

Query: 202 HSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAFPAVQPPQRPTPA 261
               L+L  +  P SP     L P          LA+ SP  P A A   +Q P  P P+
Sbjct: 625 ----LALPPLQAPPSPPASPPLSP----------LATPSPQAPNALAVHLLQAPFSPPPS 670

Query: 262 PRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPGLLKVPVPGLGPWPRVTPRDPG 321
           P +  P             +  A  PVSP +   + AP       P L   P   P  P 
Sbjct: 671 PPVQAPF------------SPPASPPVSPSATPPSQAP-------PSLAAPPLQVPPSPP 711

Query: 322 QEGELERAAQSDPRRRLSLGS-RLELPKASPSLTRFCSRSSLPTGSSVMLWPEDGDPGGP 380
               +  +A   P+    L +  L++P + P+       ++ P     +L      P   
Sbjct: 712 ASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLL----AAPPLQ 767

Query: 381 ETPGPEGPLPLQPRG-PVPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQ 439
             P P   LP+ P   P P +P  +     +AL              P+  L   PL   
Sbjct: 768 VPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 827

Query: 440 LGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPE 499
             +    L      L+    PP +P   + +R P  GP     +   P L   L  G P 
Sbjct: 828 PPQAPPVLAA--PLLQVPPSPPASPTLQAPRRPPTPGPDT---SVSGPRLTLALAPGPPP 882

Query: 500 PPG------MLGP----------AAPQPFSGHTTKCEADSSV-PPPGLPLAA 534
           PP       + GP          + P+   G+ +  E  ++  PPP   LAA
Sbjct: 883 PPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA 934



 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 112/429 (26%), Positives = 143/429 (33%), Gaps = 71/429 (16%)

Query: 133 RAKGSPGPPPPVARATRKGPGPSGLLPESWKP------GMGG---DPRGVGAGDMASAGP 183
           R  GSP PPPPV  A  +  G +G +    KP      G+GG         AG   SAG 
Sbjct: 28  RPPGSPRPPPPVTPAALRVLGAAGAVGR--KPLAERAGGIGGATIPESAPRAGPTRSAGT 85

Query: 184 EGSVPCYPPPAPGEFPEAHSLHLSLLG-VNYPLSPGLFSYLGP----SLAAAAHVPFLAS 238
               P   PPA G    A     +  G V+ P      +  GP     L  +A       
Sbjct: 86  SSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARG 145

Query: 239 ASPLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPA 298
            +   P  +A  A        P P    P +   +      +AA  +  +   +PS  P 
Sbjct: 146 KATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS------RAAGTEVGLPRPAPSARPR 199

Query: 299 PGLLKVPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCS 358
           P       P  GP   V+        E   AA    RRR S G  L+ P AS SL+   +
Sbjct: 200 P-------PTEGPRKSVSSASEHSTTEPSPAA----RRRPSAGGGLQRP-ASRSLSSSAT 247

Query: 359 RSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARV 418
             S P  S          P  P  P P+G   L+P    P       +D   ALG  +  
Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR-----KDAAPALGPLS-- 300

Query: 419 EQRLGQLGPAGGLA-PRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGP 477
              L    P+G  A P P  +                  A  PP  PL   +  AP   P
Sbjct: 301 SSPLATPSPSGTKARPVPPPDNAA-----------TPLPATLPPSPPLATPLPLAP-PSP 348

Query: 478 QALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLP------ 531
            A       P   P  T  +  PP M  P    P S  T        +PP  +P      
Sbjct: 349 SAPPSLQTLP--SPPATPPSQAPPSMTTPPMQAPPSLQT--------IPPIQVPHSLTSP 398

Query: 532 -LAAPDDPV 539
            L AP  P+
Sbjct: 399 SLQAPPSPL 407



 Score = 38.1 bits (87), Expect = 0.022
 Identities = 48/151 (31%), Positives = 57/151 (37%), Gaps = 26/151 (17%)

Query: 64   SLSLLLDSPDWACRRGSTTPRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADIHS 123
            S S  L  PD A    S T      TP+     D G  P+G     A+P PD  +A  H 
Sbjct: 887  SPSSTLSGPDLAGHSSSATS-----TPEELRGYDSG--PEGG--AAASPPPDAELAACHP 937

Query: 124  LHCGGGPKSRA--KGSPGPPPPVARATRKGPGPSGLL--------PESWKPGMG----GD 169
                 GP      +G+PG P P   AT  GPG +  L        PES  P  G    G 
Sbjct: 938  AAWSRGPAPPLAFRGAPGAPLPWPPAT--GPGSADGLCTIYETEGPESATPAPGALDPGP 995

Query: 170  PRGVGAGDMASAGPEGSVPCYPPPAP-GEFP 199
              G   G  A+    G+    P  A  GE P
Sbjct: 996  SPGTSGGKAAAGAGAGASSRSPKQARLGELP 1026


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 132/499 (26%), Positives = 170/499 (34%), Gaps = 130/499 (26%)

Query: 129  GPKSRAKGSPGPPPPVARATRKG----PGPSGLLPESWKPGMGGDPRGVGA-GDMASAGP 183
            GPK   +G PG P     + + G    PGP G      +PG+ G P   G  GDM   GP
Sbjct: 979  GPKGY-QGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGP 1037

Query: 184  EG--------SVPCYP--PPAPGEFPEAHSLHLSLLGV-------------NYPLSPGLF 220
            +G         VP  P  P  PG+  +     +S +G+              YP +PG+ 
Sbjct: 1038 QGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIK 1097

Query: 221  SYLG-PSLAAAAHVP----------FLASASPLLPPATAFPAVQP--PQRPTPAPRLYYP 267
              +G P L      P          F  +  P  P   + P   P  P  P P     +P
Sbjct: 1098 GSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHP 1157

Query: 268  LLLEHTLGLPAGKAALAKAPV-SPRSPSGTPA-PGLLKVPVPGL---------GPWPRV- 315
                   G P  K    +  +  P    G P  PG      PGL         G  P + 
Sbjct: 1158 ----GQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIP 1213

Query: 316  -TPRDPGQEGELE----RAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVML 370
              P  PG +GE         Q  P    S G  LE PK +P                   
Sbjct: 1214 GNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPG------------------ 1255

Query: 371  WPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGG 430
                G PG P  PGPEGP  L   G + G   + G+     L          G  GP  G
Sbjct: 1256 --PQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLK------GDQGPP-G 1306

Query: 431  LAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPA-KGPQALGEAWGRPEL 489
            L   P R  L  ++ +              P  P    V   P  KGP  +  + G PE 
Sbjct: 1307 LQGNPGRPGLNGMKGD--------------PGLP---GVPGFPGMKGPSGVPGSAG-PEG 1348

Query: 490  GPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLPLAAPDDPVIPGSGWGTCV 549
             P L  G P PPG+ GP      SG +   + D+   PPG+P   P    +PG       
Sbjct: 1349 EPGLI-GPPGPPGLPGP------SGQSIIIKGDAG--PPGIP-GQPGLKGLPG------- 1391

Query: 550  ATRSSQTPEAVCGLQSPQG 568
                 Q P+ + G   P G
Sbjct: 1392 ----PQGPQGLPGPTGPPG 1406



 Score = 59.3 bits (142), Expect = 9e-09
 Identities = 137/511 (26%), Positives = 172/511 (33%), Gaps = 95/511 (18%)

Query: 85   PHAP-TPDRPGESDPGRQPQGARPTG----AAPAPDLVVADIHSLHCGGGPKSRAKGSPG 139
            P AP TP R G   P   P    P G    A P P      +       GPK   +G PG
Sbjct: 724  PGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPP-GPPGLPGFKGALGPKGD-RGFPG 781

Query: 140  PPPPVARATRKG-PGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCYPPPA---- 194
            PP P  R    G PGP G +  + +PG  G P   G G     GP G       P     
Sbjct: 782  PPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGI 841

Query: 195  PGEFPEAHSLHLSLLG----------------VNYPLSPGLFSYLGPSLAAAAHVPFLAS 238
            PGE  +     L + G                +  P SPGL     P  A A+  P    
Sbjct: 842  PGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGL-----PGKAGASGFPGTKG 896

Query: 239  ASPLL-PPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTP 297
               ++ PP    P   P +   P  +    L  +  L  P G+      P  P  P G  
Sbjct: 897  EMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLP-GPPGPM 955

Query: 298  APGLL----KVPVPGLGPWPRVT--------PRDPGQEGELERAAQSDPRRRLSLGSRLE 345
             P LL    +   PGL   P V+        P DPGQ G   +     P           
Sbjct: 956  DPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPG--------- 1006

Query: 346  LPKASPSLTRFCSRSSLPTGSSVMLWPED-----GDPGGPETPGPEGPLPLQPRGPVPGS 400
             PK +P L           G   ++ P       GD G P   G EG  P  P G VPG 
Sbjct: 1007 -PKGNPGL----------PGQPGLIGPPGLKGTIGDMGFPGPQGVEG--PPGPSG-VPGQ 1052

Query: 401  PEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRP 460
            P   G  L    GD  + +  +  +G  G   P+      G+  L     +  ++ +V  
Sbjct: 1053 PGSPG--LPGQKGD--KGDPGISSIGLPGLPGPK------GEPGLPGYPGNPGIKGSVGD 1102

Query: 461  PDAPLDLSVKRAP-AKGPQALGEAWGRP-ELGPVLTGGTPEPPGMLGPAAPQPFSGHTTK 518
            P  P    +   P AKG   L    G P   GP    G P  PG+ G   P    GH  +
Sbjct: 1103 PGLP---GLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQ 1159

Query: 519  CEADSSVPPPGL-----PLAAPDDPVIPGSG 544
                     PG      P     +P  PG G
Sbjct: 1160 PGPPGEKGKPGQDGIPGPAGQKGEPGQPGFG 1190



 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 109/448 (24%), Positives = 151/448 (33%), Gaps = 82/448 (18%)

Query: 135 KGSPGPP-------PPVARATRKG----------PGPSGLLPESWKPGMGGDPRGVGA-- 175
           +G PGPP       PP      KG          PG  G   +   PG+ GDP   G   
Sbjct: 266 RGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPG 325

Query: 176 --------GDMASAGPEGSVPCYPPPAPGEFPEAHSLHLSLLG-VNYPLSPGLFSYLG-P 225
                   GD    GP G V   P P  G       + +   G +  P  PG     G P
Sbjct: 326 RDGEKGQKGDTGPPGPPGLV--IPRPGTG-------ITIGEKGNIGLPGLPGEKGERGFP 376

Query: 226 SLAAAAHVPFLASASPLLPPAT-AFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALA 284
            +     +P    A+ + PP    FP  +  +     P +  P         P G     
Sbjct: 377 GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPG--------PPGLDGQP 428

Query: 285 KAP--VSPRSPSGTPAPGLLKVPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGS 342
            AP    P  P+G   P   ++  PG  P P  +P D G +GE              +G+
Sbjct: 429 GAPGLPGPPGPAGPHIPPSDEICEPG-PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGT 487

Query: 343 RLELPKASPSLTRFCSRSSLPTGSSVMLWP-EDGDPGGPETPGPEGPLPLQPRGP----V 397
            +  P   P L        LP     + +P + G+ G     GP+G LP  P  P     
Sbjct: 488 GISGPPGQPGLP------GLPGPPGSLGFPGQKGEKGQAGATGPKG-LPGIPGAPGAPGF 540

Query: 398 PGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQA 457
           PGS    G+ LT     +  ++   G+LG  G      L    G+           L   
Sbjct: 541 PGSKGEPGDILT-----FPGMKGDKGELGSPGAPGLPGLPGTPGQ---------DGLPGL 586

Query: 458 VRPPDAPLDLSVK--RAPAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGH 515
             P   P  ++ K  R P   P   G       +GP   G    PPG +G    Q  +G+
Sbjct: 587 PGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFG----PPGPVGEKGIQGVAGN 642

Query: 516 TTKCEADSSVPPPGLPLAAPDDPVIPGS 543
             +         PG  +  P  P +PG+
Sbjct: 643 PGQPGIPGPKGDPGQTITQPGKPGLPGN 670



 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 80/287 (27%), Positives = 101/287 (35%), Gaps = 47/287 (16%)

Query: 78   RGSTTPRPHAPTPDRPGESDPGRQPQGARPTG--AAPAPDLVVADIHSLHCGGGPKSRAK 135
            +G + P  +   P  PG    G  P    P G    P  D +          G P     
Sbjct: 1133 KGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQK---GEPGQPGF 1189

Query: 136  GSPGPPPPVARATRKG-------------PGPSGLLPESWKPGMGGDPRGVGAGDMASAG 182
            G+PGPP     + +KG             PGP G       PG+ G P   G+   A  G
Sbjct: 1190 GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEG 1249

Query: 183  PEGSV-PCYPPPAPG----EFPEAHSLHLSLLG-VNYPLSPGLFSYLG-------PSLAA 229
            P+G+  P  PP  PG    E P     +  + G    P  PGL    G       P L  
Sbjct: 1250 PKGNPGPQGPPGRPGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQG 1309

Query: 230  AAHVPFL--ASASPLLPPATAFPAVQPPQ------RPTPAPRLYYPLLLEHTLGLPAGKA 281
                P L      P LP    FP ++ P        P   P L  P       G P+G++
Sbjct: 1310 NPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPG-PSGQS 1368

Query: 282  ALAKAPVSPRSPSGTPAPGLLKVPVP----GLGPWPRVTPRDPGQEG 324
             + K    P  P     PGL  +P P    GL P P   P DPG+ G
Sbjct: 1369 IIIKGDAGP--PGIPGQPGLKGLPGPQGPQGL-PGPTGPPGDPGRNG 1412



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 117/457 (25%), Positives = 151/457 (33%), Gaps = 136/457 (29%)

Query: 129 GPKSRA--KGSPGPPPPVARATRKGPGPSGLLPESWKPGMGG-----DPRGVGA--GDMA 179
           GP+ +    G PGPP P  +  R  PG  G       PGM G      P+G+    G   
Sbjct: 72  GPRGQKGDDGIPGPPGP--KGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKG 129

Query: 180 SAGPEGSV-------PCYPPPAPGEFPEAHSLHLSLL-----GVNYPLSPGLFSYLGPSL 227
             G  GS        P  PP  PG   E  S+ +S L        YP  PG+    GP+ 
Sbjct: 130 ERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPT- 188

Query: 228 AAAAHVPFLASASPLLPPATAFPAVQPPQRP--TPAPRLYYPLLLEHTLGL--------- 276
                        P+ PP    P +  P  P   P P+    L  +   G          
Sbjct: 189 ---------GIPGPIGPPGP--PGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGP 237

Query: 277 --PAGKAALAKAPVSPRSPSGTPA-PGLLKVPVPGLGPWPRVTPRDPGQEGELERAAQSD 333
             P G+ +  K P+      G    PG    P P   P  R  P  PG E + E+  Q +
Sbjct: 238 PGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGP---PGIRGPPGPPGGE-KGEKGEQGE 293

Query: 334 PRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQP 393
           P +R   G                               E+G PG P  PG  G      
Sbjct: 294 PGKRGKPGKD----------------------------GENGQPGIPGLPGDPG------ 319

Query: 394 RGPVPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQA 453
               PG P   GE   +  GD        G  GP G + PRP            +TI + 
Sbjct: 320 ---YPGEPGRDGEKGQK--GD-------TGPPGPPGLVIPRPGTG---------ITIGE- 357

Query: 454 LEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEPPG--MLGPAAPQP 511
            +  +  P  P +        KG +      G P        G P PPG  ++GP  P  
Sbjct: 358 -KGNIGLPGLPGE--------KGERGFPGIQGPP--------GLPGPPGAAVMGPPGPPG 400

Query: 512 FSGHTTKCEADSSVP------PPGLPLAAPDDPVIPG 542
           F G   + + D   P      PPGL    P  P +PG
Sbjct: 401 FPGERGQ-KGDEGPPGISIPGPPGLD-GQPGAPGLPG 435



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 118/490 (24%), Positives = 154/490 (31%), Gaps = 93/490 (18%)

Query: 90  PDRPGESDPGRQPQGARPTGAA------PAPDLVVADIHSLHCGGGPKSRAK-------G 136
           P  PG      Q     P G        P   + + +  ++   G P  + +       G
Sbjct: 321 PGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQG 380

Query: 137 SPGPPPPVARATRKGPGPSGLLPESWK--------------PGMGGDPRGVG-AGDMASA 181
            PG P P   A    PGP G   E  +              PG+ G P   G  G    A
Sbjct: 381 PPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPA 440

Query: 182 GPE---GSVPCYP-PPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLA 237
           GP        C P PP P   P    L     GV        F+ +G  ++     P L 
Sbjct: 441 GPHIPPSDEICEPGPPGPPGSPGDKGLQ-GEQGVKGDKGDTCFNCIGTGISGPPGQPGLP 499

Query: 238 SASPLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTP 297
              P  P +  FP  +  +    A               P G   +  AP +P  P    
Sbjct: 500 GL-PGPPGSLGFPGQKGEKGQAGATG-------------PKGLPGIPGAPGAPGFPGSKG 545

Query: 298 APG-LLKVP----------VPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLEL 346
            PG +L  P           PG    P + P  PGQ+G                   L  
Sbjct: 546 EPGDILTFPGMKGDKGELGSPGAPGLPGL-PGTPGQDGL----------------PGLPG 588

Query: 347 PKASPSLTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGE 406
           PK  P    F      P    +   P +  P GP   GP GP+  +    V G+P   G 
Sbjct: 589 PKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPG- 647

Query: 407 DLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLD 466
            +    GD  +   + G+     GL   P R+  G +    L     L      P  P  
Sbjct: 648 -IPGPKGDPGQTITQPGK----PGLPGNPGRD--GDVG---LPGDPGLPGQPGLPGIPGS 697

Query: 467 LSVKRAPAKGPQALGEAWGRPEL-GPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSV 525
                 P  G        G P + GP    GTP   G+ GP  P  F G   K E   ++
Sbjct: 698 KGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG--PKGEPGFAL 755

Query: 526 P----PPGLP 531
           P    PPGLP
Sbjct: 756 PGPPGPPGLP 765



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 113/443 (25%), Positives = 136/443 (30%), Gaps = 84/443 (18%)

Query: 136  GSPGPPPPVARATRKG-PGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEG-----SVPC 189
            G PG P    R    G PG  GL  +   PG+ G     G   +   GP G      +P 
Sbjct: 663  GKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIP- 721

Query: 190  YPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAF 249
             PP APG            +G+  P  PG   + GP         F     P  P    F
Sbjct: 722  GPPGAPGT--------PGRIGLEGP--PGPPGFPGPK----GEPGFALPGPPGPPGLPGF 767

Query: 250  PAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALA-KAPVSPRSPSGTPAPGLLKVPVPG 308
                 P+     P    P       GLP  K  +       P  P G P  G+   P P 
Sbjct: 768  KGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPP 827

Query: 309  LGPWPRVTP---------RDPGQEG------ELERAAQSDPRRRLSLGSRLELPKASPSL 353
              P P   P          DPG  G        ER +   P     +G     P  SP L
Sbjct: 828  GIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIG-----PPGSPGL 882

Query: 354  TRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVG----EDLT 409
                  S  P           G+ G    PGP GPL +  R  VPG     G      L 
Sbjct: 883  PGKAGASGFP--------GTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLP 934

Query: 410  RALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSV 469
               G+    +   G  GP G + P  L  +  K                  P  P    V
Sbjct: 935  GPTGEKGS-KGEPGLPGPPGPMDPNLLGSKGEK----------------GEPGLPGIPGV 977

Query: 470  KRAPAKGPQALGEAWGRPEL----------GPVLTGGTPEPPGMLGPAAPQPFSGHTTKC 519
              +  KG Q L    G+P L          GP    G P  PG++GP   +   G     
Sbjct: 978  --SGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFP 1035

Query: 520  EADSSVPPPGLPLAAPDDPVIPG 542
                   PPG P   P  P  PG
Sbjct: 1036 GPQGVEGPPG-PSGVPGQPGSPG 1057



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 125/483 (25%), Positives = 152/483 (31%), Gaps = 105/483 (21%)

Query: 128 GGPKSRAKGSPGPPPPVARATRKG---------PGPSGLLPESWKPGMGGDPRGVG---- 174
           G P +   G PGPP       +KG         PGP GL  +   PG+ G P   G    
Sbjct: 386 GPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIP 445

Query: 175 -AGDMASAGPEGSVPCYPPPAPGEFP---------EAHSLHLSLLGVNY---PLSPGLFS 221
            + ++   GP G     PP +PG+           +      + +G      P  PGL  
Sbjct: 446 PSDEICEPGPPG-----PPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPG 500

Query: 222 YLGP--SLA----------AAAHVPFLASASPLLPPATAFPAVQPPQRPTPAPRLYYPLL 269
             GP  SL           A A  P      P  P A  FP      +  P   L +P  
Sbjct: 501 LPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPG----SKGEPGDILTFP-- 554

Query: 270 LEHTLGLPAGKAALAK--APVSPRSPSGTPAPGLLKVPVPGLGPW------PRVTPRDPG 321
                G+   K  L    AP  P  P      GL  +P P   P        R  P +PG
Sbjct: 555 -----GMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPG 609

Query: 322 QEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLP--TGSSVMLWPEDGDPGG 379
             G         P      G   E  K    +     +  +P   G       + G PG 
Sbjct: 610 LPGLPGNIGPMGPPGFGPPGPVGE--KGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGL 667

Query: 380 PETPGPEGP--LPLQPRGP----VPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAP 433
           P  PG +G   LP  P  P    +PG P   GE     +G    +    G  G  G   P
Sbjct: 668 PGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIG----LPGPPGPKGFPGIPGP 723

Query: 434 RPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPA------KGPQALGEAWGRP 487
                  G+I LE             PP  P     K  P        GP  L    G  
Sbjct: 724 PGAPGTPGRIGLE------------GPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKG-- 769

Query: 488 ELGPVLTGGTPEPPGMLG----PAAPQPFSGHTTKCEADSSVPPPGLP----LAAPDDPV 539
            LGP    G P PPG  G       P P  G          + PPGLP       P  P 
Sbjct: 770 ALGPKGDRGFPGPPGPPGRTGLDGLPGP-KGDVGPNGQPGPMGPPGLPGIGVQGPPGPPG 828

Query: 540 IPG 542
           IPG
Sbjct: 829 IPG 831



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 93/340 (27%), Positives = 110/340 (32%), Gaps = 74/340 (21%)

Query: 136  GSPGPPPPVARATRKG-PGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCYPPPA 194
            G PG P PV      G PGP G   E  KPG  G P    AG     G  G     PP  
Sbjct: 1143 GLPGEPGPVGGGGHPGQPGPPG---EKGKPGQDGIPGP--AGQKGEPGQPGFGNPGPPGL 1197

Query: 195  PGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAFPAVQP 254
            PG   +     L       P +PGL    GP      H  F     P  PP +  PA++ 
Sbjct: 1198 PGLSGQKGDGGLP----GIPGNPGL---PGPKGEPGFH-GFPGVQGPPGPPGSPGPALEG 1249

Query: 255  P------QRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPS--GTPA-------P 299
            P      Q P   P L  P   E   GLP G   +     +P  P   G P        P
Sbjct: 1250 PKGNPGPQGPPGRPGLPGP---EGPPGLP-GNGGIKGEKGNPGQPGLPGLPGLKGDQGPP 1305

Query: 300  GLLKVPV-PGLG-----PWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSL 353
            GL   P  PGL      P     P  PG +G       + P     L      P   P L
Sbjct: 1306 GLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIG----PPGPPGL 1361

Query: 354  TRFCSRSSLPTGSSVMLWPEDGDPG--------------GPE----------TPGPEGPL 389
                     P+G S+++  + G PG              GP+           PG  G  
Sbjct: 1362 PG-------PSGQSIIIKGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLP 1414

Query: 390  PLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQLGPAG 429
                 G   G P   G+  TR L      +   G  GP G
Sbjct: 1415 GFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPGPPG 1454


>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
          Length = 1497

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 117/457 (25%), Positives = 138/457 (30%), Gaps = 110/457 (24%)

Query: 77   RRGSTTPRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGG-PKSRA- 134
            R  +  P PH P P  PG   P        P G  P P      +  L    G P  +  
Sbjct: 646  RGAAGEPGPHGP-PGVPGSVGPKGSSGSPGPQGP-PGP----VGLQGLRGEVGLPGVKGD 699

Query: 135  KGSPGPPPPVARATRKGPGPSGLLPESWKPGMGGDPRGVG----AGDMASAGPEG----- 185
            KG  GPP P      K  GP GL  E   PGM G P  VG     G M  AGP+G     
Sbjct: 700  KGPMGPPGPKGDQGEK--GPRGLTGE---PGMRGLPGAVGEPGAKGAMGPAGPDGHQGPR 754

Query: 186  ------SVP-CYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLAS 238
                   +P    PP P   P    L         P +PG     G   A    V    S
Sbjct: 755  GEQGLTGMPGIRGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGS 814

Query: 239  ASPLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAAL-AKAPVSPRSPSGTP 297
            +   +P     P    P  P  AP    P       GLP  +  L  + P  P  P G P
Sbjct: 815  SMLTVPGPPGPPGAMGPPGPPGAPGPAGP------AGLPGHQEVLNLQGPPGPPGPRGPP 868

Query: 298  APGLLKVPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFC 357
             P +   P P  GP     P  PG  G                                 
Sbjct: 869  GPSIPGPPGP-RGPPGEGLPGPPGPPG--------------------------------- 894

Query: 358  SRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYAR 417
               S  + S   L    G PG P  PGP+G      +GP PG   H GE           
Sbjct: 895  ---SFLSNSETFL---SGPPGPPGPPGPKG-----DQGP-PGPRGHQGEQGLPGFSTSGS 942

Query: 418  VEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGP 477
                L   GP G   P+  +   G                   P  P  L +   P++G 
Sbjct: 943  SSFGLNLQGPPGPPGPQGPKGDKG------------------DPGVPGALGIPSGPSEGG 984

Query: 478  QALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSG 514
             +            +   G P PPG  GP      SG
Sbjct: 985  SS----------STMYVSGPPGPPGPPGPPGSISSSG 1011



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 82/319 (25%), Positives = 104/319 (32%), Gaps = 62/319 (19%)

Query: 275 GLPAGKAALAK-APVSPRSPSGTPA-PGLLKVPVPGLGPWPRVTPRDPGQEGELERAAQS 332
           G P  K  +    P   R   GTP  PG L  P P      + +  DPG EG + +  + 
Sbjct: 567 GSPGPKGDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGRE 626

Query: 333 DPRRRLSLGSRLEL--PKASPSLTRFCSRSSLPTGSSVM---LWPEDGDPGGPETPGPEG 387
            P     +G R E   P +     R  +    P G   +   + P+ G  G P   GP G
Sbjct: 627 GP-----MGPRGEAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPK-GSSGSPGPQGPPG 680

Query: 388 PLPLQ----------------PRGPVPGSPEHVGEDLTRALGDYARVEQ---RLGQLGPA 428
           P+ LQ                P GP PG     GE   R L     +      +G+ G  
Sbjct: 681 PVGLQGLRGEVGLPGVKGDKGPMGP-PGPKGDQGEKGPRGLTGEPGMRGLPGAVGEPGAK 739

Query: 429 GGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRPE 488
           G + P       G    + LT    +     P   P    +     +GPQ L    GRP 
Sbjct: 740 GAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGL--TGPQGPQGLPGTPGRPG 797

Query: 489 L-------------------------GPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADS 523
           +                         GP    G P PPG  GPA P    GH        
Sbjct: 798 IKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQG 857

Query: 524 SVPPPGLPLAAPDDPVIPG 542
              PPG     P  P IPG
Sbjct: 858 PPGPPG--PRGPPGPSIPG 874



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 80/326 (24%), Positives = 108/326 (33%), Gaps = 75/326 (23%)

Query: 135  KGSPGPPPPVARATRKGP-GPSGLLPESWKPGMGGDPRGVG------AGDMASA----GP 183
            +G PGP     +    GP GP GL     +PG+ G+P   G         M +     GP
Sbjct: 766  RGPPGPSGDPGKPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGP 825

Query: 184  EGSV-PCYPPPAPGEF-PEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASP 241
             G++ P  PP APG   P     H  +L +  P  P      GP       +P      P
Sbjct: 826  PGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPP-----GPRGPPGPSIP--GPPGP 878

Query: 242  LLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAP-- 299
              PP    P         P P   +    E  L  P G       P  P+   G P P  
Sbjct: 879  RGPPGEGLPG-------PPGPPGSFLSNSETFLSGPPG----PPGPPGPKGDQGPPGPRG 927

Query: 300  -----GLLKVPVPG---LGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASP 351
                 GL      G    G   +  P  PG +G   +  + DP    +LG      +   
Sbjct: 928  HQGEQGLPGFSTSGSSSFGLNLQGPPGPPGPQG--PKGDKGDPGVPGALGIPSGPSEGGS 985

Query: 352  SLTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRA 411
            S T + S                G PG P  PGP            PGS    G+++ + 
Sbjct: 986  SSTMYVS----------------GPPGPPGPPGP------------PGSISSSGQEIQQY 1017

Query: 412  LGDYARVEQ----RLGQLGPAGGLAP 433
            + +Y + +       G  GP G   P
Sbjct: 1018 ISEYMQSDSIRSYLSGVQGPPGPPGP 1043



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 43/156 (27%), Positives = 52/156 (33%), Gaps = 43/156 (27%)

Query: 393  PRGPVPGSPEHVGEDLTRALGDYARVEQRL-----------GQLGPAG--GLAPRPLREQ 439
            PRGP PG P   G+    +L DYA +  R+           G  GP G  GL      E 
Sbjct: 1107 PRGP-PGPPGASGDGSLLSL-DYAELSSRILSYMSSSGISIGLPGPPGPPGLPGTSYEEL 1164

Query: 440  LGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQAL-GEAWGRPEL--------- 489
            L  +R             V PP  P           GP  + G  W    +         
Sbjct: 1165 LSLLR------GSEFRGIVGPPGPP-----------GPPGIPGNVWSSISVEDLSSYLHT 1207

Query: 490  -GPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSS 524
             G     G P PPG  GP  P   SG      A++S
Sbjct: 1208 AGLSFIPGPPGPPGPPGPRGPPGVSGALATYAAENS 1243


>gi|122937267 lemur tyrosine kinase 3 [Homo sapiens]
          Length = 1489

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 94/370 (25%), Positives = 118/370 (31%), Gaps = 77/370 (20%)

Query: 79   GSTTPRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADIHS---------LHCGGG 129
            G T P P  P P + G  +PG + +     GA  AP     D+ S            GGG
Sbjct: 1097 GETAPGPLGPAP-KNGTLEPGTERRAPETGGAPRAPGAGRLDLGSGGRAPVGTGTAPGGG 1155

Query: 130  PKSRAKGSPG--------------PPPPVARATRKGPGPSGLLPESWKPGMGGDPRGVGA 175
            P S      G              PPPP A+  R  P P    PE    G  G P     
Sbjct: 1156 PGSGVDAKAGWVDNTRPQPPPPPLPPPPEAQPRRLEPAPPRARPEVAPEGEPGAPDSRAG 1215

Query: 176  GDMASAGPEGSVPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPF 235
            GD A +G +G      PP P                  P  P LF  LGP    +  +  
Sbjct: 1216 GDTALSG-DGD-----PPKPER--------------KGPEMPRLFLDLGPPQGNSEQIKA 1255

Query: 236  -LASASPLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPS 294
             L+  S  LPP T  P       P P PR   P       G   G+A  A AP  P    
Sbjct: 1256 RLSRLSLALPPLTLTPF------PGPGPR--RPPWEGADAGAAGGEAGGAGAP-GPAEED 1306

Query: 295  GTPAPGLLKVPVPGLGPWPRVTPRDPGQ---------------------EGELERAAQSD 333
            G       +       P     PR PG+                      G L+    +D
Sbjct: 1307 GEDEDEDEEEDEEAAAPGAAAGPRGPGRARAAPVPVVVSSADADAARPLRGLLKSPRGAD 1366

Query: 334  PRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQP 393
                  L  + ++      +T +      PT    +  P +GD   P TP P  P P  P
Sbjct: 1367 EPEDSELERKRKMVSFHGDVTVYLFDQETPTNELSVQAPPEGDT-DPSTP-PAPPTPPHP 1424

Query: 394  RGPVPGSPEH 403
              P  G P +
Sbjct: 1425 ATPGDGFPSN 1434



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 54/179 (30%), Positives = 68/179 (37%), Gaps = 28/179 (15%)

Query: 262 PRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGT----PAPGLLKVPVPGLGPWPRVTP 317
           P L  P   E    L A + +LA  P++P + +      P  G      PG GP P   P
Sbjct: 725 PALGCPHPPEDDSSLRAERGSLADLPMAPPASAPPEFLDPLMGAAAPQYPGRGPPPAPPP 784

Query: 318 RDPGQEGELERAAQSDPRRRL-SLGSRLELPKASP------SLTRFCSRSSLPTGSSV-- 368
             P      + AA  DP   + S GS L  P   P      + T F    + P G +   
Sbjct: 785 PPPPPRAPADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGAFPGGGAAEE 844

Query: 369 ------MLWPEDGDPGGPETPGPEGPLPL-----QPRGPVPGSPEH----VGEDLTRAL 412
                    PE  DPG P  P   GPLPL     +P   V  S E     + ED+TR L
Sbjct: 845 EGVPRPRAPPEPPDPGAPRPPPDPGPLPLPGPREKPTFVVQVSTEQLLMSLREDVTRNL 903



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 117/487 (24%), Positives = 155/487 (31%), Gaps = 118/487 (24%)

Query: 91   DRPGESDPGRQPQ---------GARPTGAAPAPDLVVADIHSLHCGGGPKSRAKGSPGPP 141
            +RP E+ P R P          G  PT   PAP+  +    +       ++  + +PGP 
Sbjct: 1045 ERPPETGPWRAPGPWEKTPESWGPAPTIGEPAPETSLERAPAPSAVVSSRNGGETAPGPL 1104

Query: 142  PPVARATRKGPGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCYPPPAPGEFPEA 201
             P  +     PG     PE+     GG PR  GAG +   G  G  P     APG     
Sbjct: 1105 GPAPKNGTLEPGTERRAPET-----GGAPRAPGAGRL-DLGSGGRAPVGTGTAPGG---- 1154

Query: 202  HSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAFPAVQPPQRPTPA 261
                                  GP     A   ++ +  P           QPP  P P 
Sbjct: 1155 ----------------------GPGSGVDAKAGWVDNTRP-----------QPPPPPLPP 1181

Query: 262  PRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTP---APGLLKVPVPGLGPWPRVTPR 318
            P    P  LE     PA   A  +  V+P    G P   A G   +   G  P P     
Sbjct: 1182 PPEAQPRRLE-----PAPPRA--RPEVAPEGEPGAPDSRAGGDTALSGDGDPPKP----- 1229

Query: 319  DPGQEGELERAAQSDPRRRLSLG-------------SRLELPKASPSLTRFCSRSSL-PT 364
                    ER     PR  L LG             SRL L     +LT F       P 
Sbjct: 1230 --------ERKGPEMPRLFLDLGPPQGNSEQIKARLSRLSLALPPLTLTPFPGPGPRRPP 1281

Query: 365  GSSVMLWPEDGDPGGPETPGP----------------EGPLP---LQPRGPVPGSPEHVG 405
                      G+ GG   PGP                E   P     PRGP       V 
Sbjct: 1282 WEGADAGAAGGEAGGAGAPGPAEEDGEDEDEDEEEDEEAAAPGAAAGPRGPGRARAAPVP 1341

Query: 406  EDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPL 465
              ++ A  D AR  + L +  P G  A  P   +L + R ++++ H  +   +   + P 
Sbjct: 1342 VVVSSADADAARPLRGLLK-SPRG--ADEPEDSELERKR-KMVSFHGDVTVYLFDQETPT 1397

Query: 466  DLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSV 525
            +    +AP +G          P      T   P  PG   P+    F G     E    +
Sbjct: 1398 NELSVQAPPEGDTDPSTPPAPP------TPPHPATPGDGFPSNDSGFGGSFEWAEDFPLL 1451

Query: 526  PPPGLPL 532
            PPPG PL
Sbjct: 1452 PPPGPPL 1458



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 117/499 (23%), Positives = 149/499 (29%), Gaps = 105/499 (21%)

Query: 84  RPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRAKGSPGPPPP 143
           RP  P P  P   D G  P    P  +AP P  +            P     G PG  P 
Sbjct: 444 RPPRPPPPPPPPRD-GPFPWPWPPAHSAPRPGTL----------SSPFPLLDGFPGADPD 492

Query: 144 -VARATRKGPGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCYPPPAPGEFPEAH 202
            V   T    G +  L   W+    G  RG GA            P + P +    P A+
Sbjct: 493 DVLTVTESSRGLN--LECLWEKARRGAGRGGGA------------PAWQPASAPPAPHAN 538

Query: 203 SLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASP--------LLPPATAFPAVQP 254
             +     ++ P    + S   PS+++  ++      SP          P     PA Q 
Sbjct: 539 PSNPFYEALSTPSVLPVISARSPSVSSEYYIRLEEHGSPPEPLFPNDWDPLDPGVPAPQA 598

Query: 255 PQRPTPAPRL----YYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPGLLK------V 304
           PQ P+  P+L    +   L       PA  +A     +S   P G  A   L       +
Sbjct: 599 PQAPSEVPQLVSETWASPLFPAPRPFPAQSSASGSFLLSGWDPEGRGAGETLAGDPAEVL 658

Query: 305 PVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGS----RLELPKASPSLTRFCSRS 360
              G  PW         +E E E    S      SLG     R  LP    S    CS  
Sbjct: 659 GERGTAPWV--------EEEEEEEEGSSPGEDSSSLGGGPSRRGPLPCPLCSREGACSCL 710

Query: 361 SLPTGSSVMLW---PEDGDPGGPETP-------GPEGPLPLQPRGPVPGSPEHVGEDLTR 410
            L  G +V  W   P  G P  PE         G    LP+ P  P    PE +   +  
Sbjct: 711 PLERGDAVAGWGGHPALGCPHPPEDDSSLRAERGSLADLPMAP--PASAPPEFLDPLMGA 768

Query: 411 ALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVK 470
           A   Y           P  G  P P                        PP AP D +  
Sbjct: 769 AAPQY-----------PGRGPPPAP-------------------PPPPPPPRAPADPAAS 798

Query: 471 RAPAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSG-----HTTKCEADSSV 525
             P     + G     P   P  +G   E P    P    P  G        +  A    
Sbjct: 799 PDPPSAVASPGSGLSSPGPKPGDSGYETETP--FSPEGAFPGGGAAEEEGVPRPRAPPEP 856

Query: 526 PPPGLPLAAPDDPVIPGSG 544
           P PG P   PD   +P  G
Sbjct: 857 PDPGAPRPPPDPGPLPLPG 875



 Score = 30.0 bits (66), Expect = 6.0
 Identities = 28/95 (29%), Positives = 33/95 (34%), Gaps = 14/95 (14%)

Query: 70  DSPDWACRRGSTTPRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGG 129
           D P      GS    P     D   E++    P+GA P G A   +            G 
Sbjct: 800 DPPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGAFPGGGAAEEE------------GV 847

Query: 130 PKSRAKGSPGPPPPVARATRKGPGPSGLLPESWKP 164
           P+ RA   P PP P A      PGP  L     KP
Sbjct: 848 PRPRAP--PEPPDPGAPRPPPDPGPLPLPGPREKP 880


>gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]
          Length = 680

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 119/466 (25%), Positives = 161/466 (34%), Gaps = 57/466 (12%)

Query: 135 KGSPGPPPPVARATRKGP-GPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCYPPP 193
           +G+PGPP P       GP GP G  P    PG+ G+P   G    ++ G  G VP   P 
Sbjct: 59  QGTPGPPGPAGPRGHPGPSGPPG-KPGYGSPGLQGEPGLPGPPGPSAVGKPG-VPGL-PG 115

Query: 194 APGE----FPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAF 249
            PGE     P+       L G   P  P       P +   A +          P     
Sbjct: 116 KPGERGPYGPKGDVGPAGLPGPRGPPGP-------PGIPGPAGISVPGKPGQQGPTGAPG 168

Query: 250 PAVQPPQRPTPAPRLYYPLLLEHTLGLPA--GKAALAKAPVSPRSPSGTPAPGLL-KVPV 306
           P   P ++  P          E   G P   G+  L   P  P  PSG P  G   +  V
Sbjct: 169 PRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGL-PGPQGPTGPSGPPGVGKRGENGV 227

Query: 307 PG-------------LG----PWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPK- 348
           PG             +G    P P+  P + G EG  +  A   P +    G++  LP  
Sbjct: 228 PGQPGIKGDRGFPGEMGPIGPPGPQGPPGERGPEGIGKPGAAGAPGQPGIPGTK-GLPGA 286

Query: 349 ---ASPSLTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVG 405
              A P       +  LP G      P  G PGGP   G +GP  L  +  + G P ++G
Sbjct: 287 PGIAGPPGPPGFGKPGLP-GLKGERGPA-GLPGGPGAKGEQGPAGLPGKPGLTGPPGNMG 344

Query: 406 EDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPL 465
               + +     +    G+ GPAG       + + G    +         +   P    L
Sbjct: 345 PQGPKGIPGSHGLPGPKGETGPAGPAGYPGAKGERGSPGSD--------GKPGYPGKPGL 396

Query: 466 DLSVKRAPAKGPQALGEAWGRPEL-GPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSS 524
           D         GP+      G P L GPV   G    PG  G A P+   G          
Sbjct: 397 DGPKGNPGLPGPKGDPGVGGPPGLPGPVGPAGAKGMPGHNGEAGPRGAPGIP---GTRGP 453

Query: 525 VPPPGLP--LAAPDDPVIPGSGWGTCVATRSSQTPEAVCGLQSPQG 568
           + PPG+P    +  DP  PG      +AT+    P    G   P+G
Sbjct: 454 IGPPGIPGFPGSKGDPGSPGPPGPAGIATKGLNGPTGPPGPPGPRG 499



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 115/461 (24%), Positives = 151/461 (32%), Gaps = 102/461 (22%)

Query: 90  PDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRA--KGSPGPPPPVARA 147
           P +PG+  P   P      G   AP +   +      G G   R   +G PGP  P   +
Sbjct: 155 PGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGRPGERGLPGPQGPTGPS 214

Query: 148 TRKGPGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCYPPPAPGEF-PEAHSLHL 206
              G G  G      +PG+ GD RG   G+M   GP G     P   PGE  PE      
Sbjct: 215 GPPGVGKRGENGVPGQPGIKGD-RGF-PGEMGPIGPPG-----PQGPPGERGPE------ 261

Query: 207 SLLGVNYPLSPGLFSYLG-PSLAAAAHVPFLASASPLLPPATAFPAVQPPQRPTPAPRLY 265
              G+  P + G     G P        P +A   P  PP    P + P  +    P   
Sbjct: 262 ---GIGKPGAAGAPGQPGIPGTKGLPGAPGIAG--PPGPPGFGKPGL-PGLKGERGPA-- 313

Query: 266 YPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPGLLKVPVPGLGPW-PRVTPRD---PG 321
                    GLP G  A  +     + P+G P    L  P   +GP  P+  P     PG
Sbjct: 314 ---------GLPGGPGAKGE-----QGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPG 359

Query: 322 QEGELERAAQSD-PRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVMLWPEDGDPGGP 380
            +GE   A  +  P  +   GS       S     +  +  L           DG  G P
Sbjct: 360 PKGETGPAGPAGYPGAKGERGS-----PGSDGKPGYPGKPGL-----------DGPKGNP 403

Query: 381 ETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQL 440
             PGP+G   +   G  PG P  VG    + +  +       G+ GP G       R  +
Sbjct: 404 GLPGPKGDPGV---GGPPGLPGPVGPAGAKGMPGHN------GEAGPRGAPGIPGTRGPI 454

Query: 441 GKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEP 500
           G                  PP  P     K  P           G P    + T G   P
Sbjct: 455 G------------------PPGIPGFPGSKGDPGSP--------GPPGPAGIATKGLNGP 488

Query: 501 PGMLGPAAPQPFSGHTTKCEADSSVPPPGLPLAAPDDPVIP 541
            G  GP  P+  SG       +  +P P  P   P   V+P
Sbjct: 489 TGPPGPPGPRGHSG-------EPGLPGPPGPPGPPGQAVMP 522



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 105/407 (25%), Positives = 130/407 (31%), Gaps = 65/407 (15%)

Query: 146 RATRKGPGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCYPPPAPGEFPEAHSLH 205
           R  +  PGP G       PG  G P   G G   S G +G      PP P          
Sbjct: 56  RGEQGTPGPPGPAGPRGHPGPSGPPGKPGYG---SPGLQGEPGLPGPPGPS--------- 103

Query: 206 LSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAFPAVQPPQRPTPAPRLY 265
                V  P  PGL    G                P  P     PA  P  R  P P   
Sbjct: 104 ----AVGKPGVPGLPGKPG-------------ERGPYGPKGDVGPAGLPGPRGPPGPP-- 144

Query: 266 YPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPGLLKVPVPGLGPWPRVTPRDPGQEGE 325
                    G+P             + P+G P P       PG    P V P   GQ+GE
Sbjct: 145 ---------GIPGPAGISVPGKPGQQGPTGAPGPR----GFPGEKGAPGV-PGMNGQKGE 190

Query: 326 LERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGP 385
           +   A   P  R   G +     + P        + +P    +      GD G P   GP
Sbjct: 191 MGYGAPGRPGERGLPGPQGPTGPSGPPGVGKRGENGVPGQPGI-----KGDRGFPGEMGP 245

Query: 386 EGPLPLQPRGPVPG--SPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKI 443
            G  P  P+GP PG   PE +G+           +    G  G A G+A  P     GK 
Sbjct: 246 IG--PPGPQGP-PGERGPEGIGKPGAAGAPGQPGIPGTKGLPG-APGIAGPPGPPGFGKP 301

Query: 444 RLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRPELGPV-LTG--GTPEP 500
            L  L   +        P A  +      P K P   G        GP  + G  G P P
Sbjct: 302 GLPGLKGERGPAGLPGGPGAKGEQGPAGLPGK-PGLTGPPGNMGPQGPKGIPGSHGLPGP 360

Query: 501 PGMLGPAAPQPFSGHTTKCEADSSVPPPGLP----LAAP-DDPVIPG 542
            G  GPA P  + G   +  +  S   PG P    L  P  +P +PG
Sbjct: 361 KGETGPAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPKGNPGLPG 407



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 89/332 (26%), Positives = 105/332 (31%), Gaps = 91/332 (27%)

Query: 83  PRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLV-VADIHSLH----CGGGPKSRAKGS 137
           P P  P    PGE    R P+G    GAA AP    +     L       G P     G 
Sbjct: 249 PGPQGP----PGE----RGPEGIGKPGAAGAPGQPGIPGTKGLPGAPGIAGPPGPPGFGK 300

Query: 138 PGPPP----------PVARATRKGPGPSGLLPESWKPGMGGDPRGVGA-------GDMAS 180
           PG P           P     +   GP+GL     KPG+ G P  +G        G    
Sbjct: 301 PGLPGLKGERGPAGLPGGPGAKGEQGPAGL---PGKPGLTGPPGNMGPQGPKGIPGSHGL 357

Query: 181 AGPEGSVPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASAS 240
            GP+G      P  P  +P A     S      P  PG     GP              +
Sbjct: 358 PGPKGETG---PAGPAGYPGAKGERGSPGSDGKPGYPGKPGLDGPK------------GN 402

Query: 241 PLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPA--GKAALAKAPVSP--RSPSGT 296
           P LP     P V  P      P L  P+      G+P   G+A    AP  P  R P G 
Sbjct: 403 PGLPGPKGDPGVGGP------PGLPGPVGPAGAKGMPGHNGEAGPRGAPGIPGTRGPIGP 456

Query: 297 PAPGLLKVPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRF 356
           P        +PG  P  +  P  PG  G    A +            L  P   P     
Sbjct: 457 PG-------IPGF-PGSKGDPGSPGPPGPAGIATKG-----------LNGPTGPPGPPG- 496

Query: 357 CSRSSLPTGSSVMLWPEDGDPGGPETPGPEGP 388
                 P G S       G+PG P  PGP GP
Sbjct: 497 ------PRGHS-------GEPGLPGPPGPPGP 515



 Score = 37.4 bits (85), Expect = 0.037
 Identities = 41/116 (35%), Positives = 49/116 (42%), Gaps = 18/116 (15%)

Query: 85  PHAPTPDRPGESD--PGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRAK-GSPGPP 141
           P  P P  P  +   PG   + A P GA   P      I      G P S+   GSPGPP
Sbjct: 418 PGLPGPVGPAGAKGMPGHNGE-AGPRGAPGIPG-TRGPIGPPGIPGFPGSKGDPGSPGPP 475

Query: 142 PPVARATRKGPGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCYPPPAPGE 197
            P   AT+   GP+G       PG  G PRG  +G+    GP G     PP  PG+
Sbjct: 476 GPAGIATKGLNGPTG------PPGPPG-PRG-HSGEPGLPGPPG-----PPGPPGQ 518


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 60.5 bits (145), Expect = 4e-09
 Identities = 112/395 (28%), Positives = 136/395 (34%), Gaps = 72/395 (18%)

Query: 83   PRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRAKGSP-GPP 141
            P P  P P  P  S P R P  A P  AAPA   VV          GP S    SP  PP
Sbjct: 662  PHPKVPAPFSPPPSKP-RSPNPAAPALAAPA---VVP---------GPVSTTDASPQSPP 708

Query: 142  PPVARAT--------RKGPGPSGLLPESWKPGMGGD--PRGVGAGDMASAGPEGSV--PC 189
             P    T         K   P    P S+ P       P  V     AS   E  +  P 
Sbjct: 709  TPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPN 768

Query: 190  YPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAF 249
            +PPP P   PE   L ++      P     FS   P  A  +  P L S+      +   
Sbjct: 769  WPPPPPPA-PEEQDLSMADFP---PPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATA 824

Query: 250  PAVQPPQRPTPAPRLYYPLLLE----HTLGLPAGK-AALAKAPVSPRSPSGTP--APGLL 302
              +QPP  P P P    P        H   LP  +    +K    PR   G P   P LL
Sbjct: 825  LQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLL 884

Query: 303  K------VPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSL--- 353
            +      V  PG  P P + P           +A   P RR   G    +P  S  L   
Sbjct: 885  QMVRLRSVGAPGGAPTPALGP-----------SAPQKPLRRALSGRASPVPAPSSGLHAA 933

Query: 354  --TRFCS-RSSLPTGSSVMLWPEDGDPGGPETPG-------PEGPLPLQPRGPVPGSPEH 403
               + CS  +S    S+    P + +P  P++P         +G   LQ   PV  SPE 
Sbjct: 934  VRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPV--SPE- 990

Query: 404  VGEDLTRALGDYAR--VEQRLGQLGPAGGLAPRPL 436
               DL R L    R   EQR  Q       AP P+
Sbjct: 991  TQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPV 1025



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 129/497 (25%), Positives = 169/497 (34%), Gaps = 95/497 (19%)

Query: 101 QPQGARPTGAAP------APDLVVADIHSLHCGGG----PKSRAKGSPGPPPPVARATRK 150
           QP+   P+ ++       + D +V+D  +L   GG    P+S    +   PPP   + R 
Sbjct: 403 QPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRG 462

Query: 151 GPGPSGLLPESWKPGMGGDPRGV-GAGDMASAGPEGSVPCYPPPAPGEFPEAHSLHLSLL 209
            P        S       D   +  +G ++           PPP P      HSLH   L
Sbjct: 463 SPSGGSTAEAS-------DTLSIRSSGQLSGRSVSLRKLKRPPPPPRR---THSLHQRGL 512

Query: 210 GVNYPLSPGLFSYLG-PSLAAAAHVPFLASASPLLPPATAFP--AVQPPQRPTPAPRLYY 266
            V  P  P     LG P        P L       PP T     A   P  P PA   + 
Sbjct: 513 AV--PDGP-----LGLPPKPERKQQPQLPR-----PPTTGGSEGAGAAPCPPNPA-NSWV 559

Query: 267 PLLLEHTLGLPAGKAALAKAPVSPRSPSG--TPAPGLLKVPVPGL-GPWPRVTPRDPGQE 323
           P L       P G     ++P    SPS   +   G   +P  GL GP     P  PG  
Sbjct: 560 PGLS------PGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGP-----PASPG-- 606

Query: 324 GELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSS----VMLWPEDGD--- 376
               +A    P R  SL  R      S SLT  CS SS P  S      +L P  GD   
Sbjct: 607 ----KAQPPKPERVTSL--RSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPL-GDRFV 659

Query: 377 -PGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRP 435
            P  P+ P P  P P +PR P P +P         AL   A V       GP       P
Sbjct: 660 IPPHPKVPAPFSPPPSKPRSPNPAAP---------ALAAPAVVP------GPVSTTDASP 704

Query: 436 LREQLGKIRLELLTIHQALEQAVRPPDA-PLDLSVKRAPAKGPQALGEAWGRPELG--PV 492
                 +  L  L     + +   PP + P        P K P+ + EA    E    P+
Sbjct: 705 QSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPL 764

Query: 493 LTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLPLAAPDDPVIPGSGWGTCVATR 552
                P PP    P AP+          AD   P       A  +P  P SG    V++ 
Sbjct: 765 QDPNWPPPP----PPAPE----EQDLSMADFPPPEEAFFSVASPEPAGP-SGSPELVSSP 815

Query: 553 SSQTPEAVCGLQSPQGA 569
           ++ +  A      P G+
Sbjct: 816 AASSSSATALQIQPPGS 832



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 81/327 (24%), Positives = 106/327 (32%), Gaps = 64/327 (19%)

Query: 69   LDSPDWACRRGSTTPRPHAPTP--------DRPGESDPGRQPQGARPTGAAPAPDLVVAD 120
            L  P+W        P P  P P        D P   +         P G + +P+LV + 
Sbjct: 764  LQDPNW--------PPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSP 815

Query: 121  IHSLHCGGGPKSRAKGSPGPPP--PVARATRKGPGPSGLLPESWKPGM---GGDPR-GVG 174
              S       + +  GSP PPP  P        PG    LP+    G    GG PR  VG
Sbjct: 816  AASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVG 875

Query: 175  AG----------DMASAGPEGSVPCYPPPAPGEFPEAHSLHLSLLGVNYPL---SPGLFS 221
            A            + S G  G  P    PA G       L  +L G   P+   S GL +
Sbjct: 876  APLVTPSLLQMVRLRSVGAPGGAPT---PALGPSAPQKPLRRALSGRASPVPAPSSGLHA 932

Query: 222  YLGPSLAAAAHVPFLASASPLLPPATAFPAVQPPQRPTPAPRLYYP-----LLLEHTLGL 276
             +     + A    L+SA P  PP       +PPQ P       +      L LE  +  
Sbjct: 933  AVRLKACSLAASEGLSSAQPNGPPEAE---PRPPQSPASTASFIFSKGSRKLQLERPVS- 988

Query: 277  PAGKAALAK-------------APVSPRSPSGTPAPGLLK----VPVPGLGPWPRVTPRD 319
            P  +A L +              P +P+     P P   K    VP P    +PR  P  
Sbjct: 989  PETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLT 1048

Query: 320  PGQEGELERAAQSDPRRRLSLGSRLEL 346
                  L        R     G  L+L
Sbjct: 1049 APPTNGLPHTQDRTKRELAENGGVLQL 1075



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 134/553 (24%), Positives = 181/553 (32%), Gaps = 103/553 (18%)

Query: 78  RGSTTPRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRAKGS 137
           +G +  +P + T        P        P+G + A       I S     G     +  
Sbjct: 435 KGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKL 494

Query: 138 PGPPPPVARAT---RKG----PGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCY 190
             PPPP  R     ++G     GP GL P+  +      PR    G    AG   + PC 
Sbjct: 495 KRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQPQLPRPPTTGGSEGAG---AAPCP 551

Query: 191 PPPAPGEFPEAHSLHLSLLGVNYP-LSPGLFSYLGPSLAAAAHVPFLASASPLLPP-ATA 248
           P PA    P      LS  G   P  SP     L PS   ++      S +P LPP   A
Sbjct: 552 PNPANSWVPG-----LSPGGSRRPPRSPE--RTLSPSSGYSSQ-----SGTPTLPPKGLA 599

Query: 249 FPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPGLLKVP--V 306
            P   P +   P P        E    L +  A+++ +  S  S S  PAP     P  +
Sbjct: 600 GPPASPGKAQPPKP--------ERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQIL 651

Query: 307 PGLG------PWPRVT---------PRDP--------------GQEGELERAAQSDPRRR 337
             LG      P P+V          PR P              G     + + QS P  +
Sbjct: 652 TPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQ 711

Query: 338 LSLGSRLELPKASPSLTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPL-------- 389
            +L    E P          S+   P  S     P    P  P T  PE  +        
Sbjct: 712 TTLTPLQESP--------VISKDQSPPPSP----PPSYHPPPPPTKKPEVVVEAPSASET 759

Query: 390 ---PLQ-PRGPVPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRL 445
              PLQ P  P P  P    +DL+ A  D+   E+    +       P    E +     
Sbjct: 760 AEEPLQDPNWPPPPPPAPEEQDLSMA--DFPPPEEAFFSVASPEPAGPSGSPELVSS--- 814

Query: 446 ELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRPELGPV--LTGGTPEPPGM 503
              +   A    ++PP +P       APA    A G     P+  PV    GG P P   
Sbjct: 815 PAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGP-PRED 873

Query: 504 LGPAAPQPFSGHTTKCE---ADSSVPPPGLPLAAPDDPVIPG-SGWGTCVATRSSQTPEA 559
           +G     P      +     A    P P L  +AP  P+    SG  + V   SS    A
Sbjct: 874 VGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAA 933

Query: 560 V----CGLQSPQG 568
           V    C L + +G
Sbjct: 934 VRLKACSLAASEG 946


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 131/518 (25%), Positives = 164/518 (31%), Gaps = 90/518 (17%)

Query: 77  RRGSTTPRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRA-- 134
           +RG T P     +P  PG       P    PTG+                  GP   A  
Sbjct: 403 QRGETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGT--------------SGPPGSAGP 448

Query: 135 KGSPGPP----PPVARATRKGPGPSGLLPESWKPGMGGDPRGVGA-----GDMASAGPEG 185
            GSPGP     P   R     PG  G   E+   G  G P G+       G+    GP G
Sbjct: 449 PGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPG-PHGIQGPIGPPGEEGKRGPRG 507

Query: 186 SVPCYPPPAP-GEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLP 244
                 PP P GE     +         +P S GL    GP  A     P  +S     P
Sbjct: 508 DPGTVGPPGPVGERGAPGNR-------GFPGSDGL---PGPKGAQGERGPVGSSG----P 553

Query: 245 PATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPGLLKV 304
             +     +P +   P  R    L     +  P GK     AP     P    + G+   
Sbjct: 554 KGSQGDPGRPGEPGLPGAR---GLTGNPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQ 610

Query: 305 PVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLEL----PKASPSLT--RFCS 358
           P     P P+ +  DPG+ GE   A    P +R + G   E+    P   P L   R   
Sbjct: 611 PGSMGLPGPKGSSGDPGKPGEAGNAGV--PGQRGAPGKDGEVGPSGPVGPPGLAGERGEQ 668

Query: 359 RSSLPTGSSVMLWP-----EDGDPGGPETPGPEGPL-PLQPRGPVPGSPEHVGEDLTRAL 412
               PTG   +  P     E G PG    PG  G + PL PRG   G+P   GE     L
Sbjct: 669 GPPGPTGFQGLPGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGE-RGNPGERGEPGITGL 727

Query: 413 GDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRA 472
                +    G  GP G   P       G                   P     +  +R 
Sbjct: 728 PGEKGMAGGHGPDGPKGSPGPSGTPGDTG-------------------PPGLQGMPGERG 768

Query: 473 PAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLPL 532
            A  P   G+  G  E G   T G     G+ GP  P   +G T     +   P P   +
Sbjct: 769 IAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAGPT----GEKGEPGPRGLV 824

Query: 533 AAPDDPVIPGSGWGTCVATRSSQTPEAVCGLQSPQGAE 570
             P     PGS        R    P    G   PQG +
Sbjct: 825 GPPGSRGNPGS--------RGENGPTGAVGFAGPQGPD 854



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 107/429 (24%), Positives = 140/429 (32%), Gaps = 100/429 (23%)

Query: 127 GGGPKSRAKGSPGPPPPVARATRKGP-GPSGLLPESWKPGMGGDPRGVG-AGDMASAGPE 184
           GG   +   G PG P P+     +GP GP G   E  +PG  G+P  VG AG   + G  
Sbjct: 231 GGAGPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFP 290

Query: 185 GSVPCYPPPAPGEFPEAHSLHLSLLGVNYPL-SPGLFSYLGPSLAAAAHVPFLASASPLL 243
           G+     P  PG   + H  H  L G    + +PG     GP+              P+ 
Sbjct: 291 GA-----PGLPG--LKGHRGHKGLEGPKGEVGAPGSKGEAGPT-------------GPMG 330

Query: 244 PPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPGLLK 303
                 P   P +R    P+           G P  + A            G P P +  
Sbjct: 331 AMGPLGPRGMPGERGRLGPQ-----------GAPGQRGA--------HGMPGKPGP-MGP 370

Query: 304 VPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLEL----PKASPSL-----T 354
           + +PG   +    P +PG +GE        P      G R E     P  SP L     T
Sbjct: 371 LGIPGSSGF----PGNPGMKGEAGPTGARGPEG--PQGQRGETGPPGPVGSPGLPGAIGT 424

Query: 355 RFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGD 414
                +  PTGS     P  G  G P +PGP+G    Q     PG P   G         
Sbjct: 425 DGTPGAKGPTGSPGTSGP-PGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFK------- 476

Query: 415 YARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPA 474
                   G+ GP G   P  ++  +G                  PP        KR P 
Sbjct: 477 --------GEAGPKGEPGPHGIQGPIG------------------PPGE----EGKRGPR 506

Query: 475 KGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLPLAA 534
             P  +G      E G     G P   G+ GP   Q   G         S   PG     
Sbjct: 507 GDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPG----R 562

Query: 535 PDDPVIPGS 543
           P +P +PG+
Sbjct: 563 PGEPGLPGA 571



 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 145/532 (27%), Positives = 175/532 (32%), Gaps = 96/532 (18%)

Query: 93   PGESDPGRQPQGARPTG--AAPAPDLVVADIHSLHCGGGPKSRAK-GSPGPPPPVARATR 149
            PG   P   P  A PTG    P P  +V         G P SR   GS G   P      
Sbjct: 800  PGPLGP---PGPAGPTGEKGEPGPRGLV---------GPPGSRGNPGSRGENGPTGAVGF 847

Query: 150  KGP-GPSGLLPESWKPGMGGDPRGVGA-GDMASAGPEGSVPCYPPPAPGEFPEAHSLHLS 207
             GP GP G      +PG+ G+P   G  GD  S GP+G      P  P   P       +
Sbjct: 848  AGPQGPDG------QPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGGRGT 901

Query: 208  LLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAFPAVQPPQRPTPAPRLYYP 267
                     PG    +GP   A A  P    A PL  P    P   P  R  P    +  
Sbjct: 902  QGPPGATGFPGSAGRVGPPGPAGAPGP----AGPLGEPGKEGP---PGLRGDPGS--HGR 952

Query: 268  LLLEHTLGLPAGKAALAK-------APVSPRSPSGTPAP-GLLKVP-------VPGLGPW 312
            +      G P G              P  P  P+GT    G++ +P       +PGL P 
Sbjct: 953  VGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGL-PG 1011

Query: 313  PRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVMLWP 372
            P  TP   G  G         P            P   P           P     +   
Sbjct: 1012 PAGTPGKVGPTGATGDKGPPGPVGPPGSNG----PVGEPGPEGPAGNDGTPGRDGAVGER 1067

Query: 373  ED-GDPGGPETPGPEGPLPLQPRGPV--PGSPEHVGEDLTRA-LGDYARVEQR--LGQLG 426
             D GDPG    PG +G  P  P GPV  PG     G+  +R  +G   R  +R   G  G
Sbjct: 1068 GDRGDPGPAGLPGSQGA-PGTP-GPVGAPGDAGQRGDPGSRGPIGPPGRAGKRGLPGPQG 1125

Query: 427  PAGGLAPRPLREQLGKIRLELLTIHQAL--------EQAV---------RPPDAPLDLSV 469
            P G       R   G+      T  Q L        EQ           R P  P+  S 
Sbjct: 1126 PRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRGPPGPVGPSG 1185

Query: 470  KRAPAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKC------EADS 523
            K      P  LG        G V   G   PPG  GP  P    GH T          D 
Sbjct: 1186 KEG---NPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAALGDIMGHYDE 1242

Query: 524  SVPPPGLP-----LAAPDDPVIPGSGWGTCVATRSSQTPEAVCGLQSPQGAE 570
            S+P P LP      AAPDD      G    + + SSQ    +  ++SP G++
Sbjct: 1243 SMPDP-LPEFTEDQAAPDDKNKTDPGVHATLKSLSSQ----IETMRSPDGSK 1289



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 123/463 (26%), Positives = 158/463 (34%), Gaps = 60/463 (12%)

Query: 135 KGSPGPP-PPVARATR-----KG-PGPSGLLPESWKPGMGGDPRGVG-AGDMASAGPEGS 186
           +G PGP  PP ++  R     KG PGP G      +PG+ G P   G  G  +  GP+G 
Sbjct: 128 RGRPGPAGPPGSQGPRGERGPKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGPDGL 187

Query: 187 VPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPA 246
                   P     A     S LG    L PG    +GP             A P  PP 
Sbjct: 188 ------SRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVGPRGPQGLQGQ-QGGAGPTGPPG 240

Query: 247 TAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPA-----GKAALAKAPVSPRSPSGTPAPGL 301
              P    P  P  +     P       G P      G+   A +P +   P     PGL
Sbjct: 241 E--PGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNPGEVGFAGSPGARGFPGAPGLPGL 298

Query: 302 LKVPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLS-LGSRLELPKASPSLTRFCSRS 360
                      P+     PG +GE   A  + P   +  LG     P+  P       R 
Sbjct: 299 KGHRGHKGLEGPKGEVGAPGSKGE---AGPTGPMGAMGPLG-----PRGMPG-----ERG 345

Query: 361 SL-PTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGE-DLTRALGDYARV 418
            L P G+      + G  G P  PGP GPL +      PG+P   GE   T A G     
Sbjct: 346 RLGPQGAP----GQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQ 401

Query: 419 EQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPP-DAPLDLSVKRAPAKGP 477
            QR G+ GP G +    L   +G                  PP  A    S     + GP
Sbjct: 402 GQR-GETGPPGPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGP 460

Query: 478 QALGEAWGRP-------ELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGL 530
           Q +    G P       E GP    G P P G+ GP  P    G         +V PPG 
Sbjct: 461 QGIRGQPGDPGVPGFKGEAGP---KGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPG- 516

Query: 531 PL---AAPDDPVIPGSGWGTCVATRSSQTPEAVCGLQSPQGAE 570
           P+    AP +   PGS        + +Q      G   P+G++
Sbjct: 517 PVGERGAPGNRGFPGS--DGLPGPKGAQGERGPVGSSGPKGSQ 557



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 136/521 (26%), Positives = 169/521 (32%), Gaps = 81/521 (15%)

Query: 79   GSTTPRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRA--KG 136
            G   P+  +  P +PGE+     P G R    AP  D  V     +    GP   A  +G
Sbjct: 615  GLPGPKGSSGDPGKPGEAGNAGVP-GQR---GAPGKDGEVGPSGPV----GPPGLAGERG 666

Query: 137  SPGPPPPVARATRKGPGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCYPPPAPG 196
              GPP P     +  PGP G   E  KPG  G P     GD  + GP G  P      PG
Sbjct: 667  EQGPPGPTG--FQGLPGPPGPPGEGGKPGDQGVP-----GDPGAVGPLG--PRGERGNPG 717

Query: 197  EFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAFPAVQPPQ 256
            E  E                PG+    G    A  H P     SP  P  T      P  
Sbjct: 718  ERGE----------------PGITGLPGEKGMAGGHGPDGPKGSP-GPSGTPGDTGPPGL 760

Query: 257  RPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPA-PGLLKVPVPGLGPWPRV 315
            +  P  R           G P  K    +  +  +   GT    G   +P P   P P  
Sbjct: 761  QGMPGER--------GIAGTPGPKG--DRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAG 810

Query: 316  TPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVMLWP-ED 374
               + G+ G   R     P  R + GSR E          F           V   P E 
Sbjct: 811  PTGEKGEPG--PRGLVGPPGSRGNPGSRGE--NGPTGAVGFAGPQGPDGQPGVKGEPGEP 866

Query: 375  GDPGGPETPGPEG----PLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGG 430
            G  G   +PGP+G    P P  P G VPG     G         +     R+G  GPAG 
Sbjct: 867  GQKGDAGSPGPQGLAGSPGPHGPNG-VPGLKGGRGTQGPPGATGFPGSAGRVGPPGPAGA 925

Query: 431  LAP-----RPLREQLGKIRLELLTIHQALEQA-VRPPDAPLDL-----SVKRAPAKGPQA 479
              P      P +E    +R +  +  +  ++    PP  P D        +  P   P  
Sbjct: 926  PGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGP 985

Query: 480  LGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVP----PPGL--PLA 533
             G    R  +G     G    PG+ GPA   P     T    D   P    PPG   P+ 
Sbjct: 986  AGTTGQRGIVGMPGQRGERGMPGLPGPAG-TPGKVGPTGATGDKGPPGPVGPPGSNGPVG 1044

Query: 534  APDDPVIPGSGWGT-----CVATRSSQTPEAVCGLQSPQGA 569
             P  P  P    GT      V  R  +      GL   QGA
Sbjct: 1045 EP-GPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGA 1084



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 121/487 (24%), Positives = 161/487 (33%), Gaps = 93/487 (19%)

Query: 83   PRPHAPTPD--RPGES----DPGRQ----PQGARPT-GAAPAPDLVVADIHSLHCGGGPK 131
            P P  P  +  +PG+     DPG      P+G R   G    P +          GG   
Sbjct: 680  PGPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGITGLPGEKGMAGGHGP 739

Query: 132  SRAKGSPGPPPPVARATRKG----PGPSGLLPESWKPGMGGDPRGVGA-GDMASAGPEGS 186
               KGSPGP          G    PG  G+   +  PG  GD  G+G  G   +AG +G+
Sbjct: 740  DGPKGSPGPSGTPGDTGPPGLQGMPGERGI---AGTPGPKGDRGGIGEKGAEGTAGNDGA 796

Query: 187  V----PCYPPPAPGEFPEAHSLHLSLLGVNYPL----SPGLFSYLGPSLAAAAHVPFLAS 238
                 P  PP   G  P          G+  P     +PG     GP+ A    V F   
Sbjct: 797  RGLPGPLGPPGPAG--PTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGA----VGFAGP 850

Query: 239  ASPLLPPATAFPAVQPPQRP---TPAPRLYYPLLLEH-TLGLPAGKAALAKAPVSPRSPS 294
              P   P       +P Q+    +P P+        H   G+P  K    +    P   +
Sbjct: 851  QGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLKGG--RGTQGPPGAT 908

Query: 295  GTP-APGLLKVPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSL 353
            G P + G +  P P   P P     +PG+EG      + DP     +G R     A P  
Sbjct: 909  GFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGP--PGLRGDPGSHGRVGDR---GPAGP-- 961

Query: 354  TRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPL-PLQPRGP--VPGSPEHVGEDLTR 410
                     P G       + GDPG    PGP+GP  P    G   + G P   GE    
Sbjct: 962  ---------PGGPG-----DKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMP 1007

Query: 411  ALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPP--DAPLDLS 468
             L   A    ++G  G  G   P                        V PP  + P+   
Sbjct: 1008 GLPGPAGTPGKVGPTGATGDKGP---------------------PGPVGPPGSNGPVGEP 1046

Query: 469  VKRAPAKGPQ------ALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEAD 522
                PA          A+GE   R + GP    G+   PG  GP      +G      + 
Sbjct: 1047 GPEGPAGNDGTPGRDGAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSR 1106

Query: 523  SSVPPPG 529
              + PPG
Sbjct: 1107 GPIGPPG 1113



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 43/140 (30%), Positives = 50/140 (35%), Gaps = 29/140 (20%)

Query: 72   PDWACRRGSTTPRPHAPTPDRPGESDPGRQPQ----GARPTGAAPAPDLVVADIHSLHCG 127
            P  A +RG   P P  P  D+    D G + Q    G       P P            G
Sbjct: 1112 PGRAGKRG--LPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPP-----------G 1158

Query: 128  GGPKSRAKGSPGPPPPVARATRKGPGPSGLLPESWKPGMGGD--PRGVGAGDMASAGPEG 185
               +  + G PGP  P     R  PGP G   +   PG  G   P GV  G +  AGPEG
Sbjct: 1159 PNGEQGSAGIPGPFGP-----RGPPGPVGPSGKEGNPGPLGPIGPPGV-RGSVGEAGPEG 1212

Query: 186  SV----PCYPPPAPGEFPEA 201
                  P  PP  PG    A
Sbjct: 1213 PPGEPGPPGPPGPPGHLTAA 1232


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 59.7 bits (143), Expect = 7e-09
 Identities = 122/514 (23%), Positives = 167/514 (32%), Gaps = 95/514 (18%)

Query: 77  RRGSTTPRPHAPTP-----DRPGESDPG--RQPQGARPTGAAPAPDLVVADIHSLHCGGG 129
           RR ++ P P  P+P      R   ++ G  R    ARP      P   V+   S H    
Sbjct: 152 RRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSA-SEHSTTE 210

Query: 130 PKSRAKGSP----GPPPPVARATRKGPGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEG 185
           P   A+  P    G   P +R+      P    P    P   G PR       +   P+G
Sbjct: 211 PSPAARRRPSAGGGLQRPASRSLSSSATPLSS-PARSGPSARGTPRA--PAHPSQPKPKG 267

Query: 186 SVPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPP 245
                PP       +A                       P+L   +  P LA+ SP  PP
Sbjct: 268 LQALRPPQVTPPRKDA----------------------APALGPLSSSP-LATPSPSAPP 304

Query: 246 ATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPGLLKVP 305
           +   P+  P  +  P+P    P     +LG P  +A  +  P  P SP  TP P   + P
Sbjct: 305 S---PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP---QAP 358

Query: 306 VPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRL-----ELPKASPSLTRFCSRS 360
            P L   P   P  P     L   A   P+   +L   L       P + P    F   +
Sbjct: 359 -PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 417

Query: 361 SLPTGSS-----------------VMLWPEDGDPGGPE-TPGPEGP-----LPLQPRGPV 397
           S P   S                 V   P    P  P  TP P+ P      PLQ   P 
Sbjct: 418 SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP 477

Query: 398 PGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQA 457
           P +P  +     +AL              P+  L   PL     +    L      L+  
Sbjct: 478 PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA--PLLQVP 535

Query: 458 VRPPDAPLDLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEPPG------MLGP----- 506
             PP +P   + +R P  GP     +   P L   L  G P PP       + GP     
Sbjct: 536 PSPPASPTLQAPRRPPTPGPDT---SVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGH 592

Query: 507 -----AAPQPFSGHTTKCEADSSV-PPPGLPLAA 534
                + P+   G+ +  E  ++  PPP   LAA
Sbjct: 593 SSSATSTPEELRGYDSGPEGGAAASPPPDAELAA 626



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 118/465 (25%), Positives = 154/465 (33%), Gaps = 80/465 (17%)

Query: 133 RAKGSPGPPPPVARATRKGPGPSGLLPESWKPGMGGDPRGVGAGDMASAGPE-GSVPCYP 191
           R  GSP PPPPV  A  +  G +G +    KP +     G+G   +  + P  G      
Sbjct: 28  RPPGSPRPPPPVTPAALRVLGAAGAVGR--KP-LAERAGGIGGATIPESAPRAGPTRTSR 84

Query: 192 PPAPGEFPEAHSLHLSLLG-VNYPLSPGLFSYLGP----SLAAAAHVPFLASASPLLPPA 246
           PPA G    A     +  G V+ P      +  GP     L  +A        +   P  
Sbjct: 85  PPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKR 144

Query: 247 TAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPGLLKVPV 306
           +A  A        P P    P +   +      +AA  +  +   +PS  P P       
Sbjct: 145 SALSAGARRDTSGPTPGTPSPAMARRS------RAAGTEVGLPRPAPSARPRP------- 191

Query: 307 PGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPTGS 366
           P  GP   V+        E   AA    RRR S G  L+ P AS SL+   +  S P  S
Sbjct: 192 PTEGPRKSVSSASEHSTTEPSPAA----RRRPSAGGGLQRP-ASRSLSSSATPLSSPARS 246

Query: 367 SVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYA---------- 416
                     P  P  P P+G   L+P    P       +D   ALG  +          
Sbjct: 247 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR-----KDAAPALGPLSSSPLATPSPS 301

Query: 417 -----RVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQ------AVRPPDAP- 464
                     L  L       P      LG   L+    H  L        A  PP AP 
Sbjct: 302 APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQ--ATHSFLPSPPLSPLATPPPQAPP 359

Query: 465 -LDLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADS 523
            L L   +AP   P +       P L P+ T     P  +       PFS          
Sbjct: 360 ALALPPLQAPPSPPAS-------PPLSPLATPSPQAPNALAVHLLQAPFS---------- 402

Query: 524 SVPPPGLPLAAPDDPVIPGSGWGTCVATRSSQTPEAVCG--LQSP 566
             PPP  P+ AP  P  P S   +  AT  SQ P ++    LQ P
Sbjct: 403 --PPPSPPVQAPFSP--PASPPVSPSATPPSQAPPSLAAPPLQVP 443



 Score = 38.1 bits (87), Expect = 0.022
 Identities = 48/151 (31%), Positives = 57/151 (37%), Gaps = 26/151 (17%)

Query: 64  SLSLLLDSPDWACRRGSTTPRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADIHS 123
           S S  L  PD A    S T      TP+     D G  P+G     A+P PD  +A  H 
Sbjct: 579 SPSSTLSGPDLAGHSSSATS-----TPEELRGYDSG--PEGG--AAASPPPDAELAACHP 629

Query: 124 LHCGGGPKSRA--KGSPGPPPPVARATRKGPGPSGLL--------PESWKPGMG----GD 169
                GP      +G+PG P P   AT  GPG +  L        PES  P  G    G 
Sbjct: 630 AAWSRGPAPPLAFRGAPGAPLPWPPAT--GPGSADGLCTIYETEGPESATPAPGALDPGP 687

Query: 170 PRGVGAGDMASAGPEGSVPCYPPPAP-GEFP 199
             G   G  A+    G+    P  A  GE P
Sbjct: 688 SPGTSGGKAAAGAGAGASSRSPKQARLGELP 718


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score = 59.3 bits (142), Expect = 9e-09
 Identities = 137/511 (26%), Positives = 172/511 (33%), Gaps = 95/511 (18%)

Query: 85   PHAP-TPDRPGESDPGRQPQGARPTG----AAPAPDLVVADIHSLHCGGGPKSRAKGSPG 139
            P AP TP R G   P   P    P G    A P P      +       GPK   +G PG
Sbjct: 724  PGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPP-GPPGLPGFKGALGPKGD-RGFPG 781

Query: 140  PPPPVARATRKG-PGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCYPPPA---- 194
            PP P  R    G PGP G +  + +PG  G P   G G     GP G       P     
Sbjct: 782  PPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGI 841

Query: 195  PGEFPEAHSLHLSLLG----------------VNYPLSPGLFSYLGPSLAAAAHVPFLAS 238
            PGE  +     L + G                +  P SPGL     P  A A+  P    
Sbjct: 842  PGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGL-----PGKAGASGFPGTKG 896

Query: 239  ASPLL-PPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTP 297
               ++ PP    P   P +   P  +    L  +  L  P G+      P  P  P G  
Sbjct: 897  EMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLP-GPPGPM 955

Query: 298  APGLL----KVPVPGLGPWPRVT--------PRDPGQEGELERAAQSDPRRRLSLGSRLE 345
             P LL    +   PGL   P V+        P DPGQ G   +     P           
Sbjct: 956  DPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPG--------- 1006

Query: 346  LPKASPSLTRFCSRSSLPTGSSVMLWPED-----GDPGGPETPGPEGPLPLQPRGPVPGS 400
             PK +P L           G   ++ P       GD G P   G EG  P  P G VPG 
Sbjct: 1007 -PKGNPGL----------PGQPGLIGPPGLKGTIGDMGFPGPQGVEG--PPGPSG-VPGQ 1052

Query: 401  PEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRP 460
            P   G  L    GD  + +  +  +G  G   P+      G+  L     +  ++ +V  
Sbjct: 1053 PGSPG--LPGQKGD--KGDPGISSIGLPGLPGPK------GEPGLPGYPGNPGIKGSVGD 1102

Query: 461  PDAPLDLSVKRAP-AKGPQALGEAWGRP-ELGPVLTGGTPEPPGMLGPAAPQPFSGHTTK 518
            P  P    +   P AKG   L    G P   GP    G P  PG+ G   P    GH  +
Sbjct: 1103 PGLP---GLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQ 1159

Query: 519  CEADSSVPPPGL-----PLAAPDDPVIPGSG 544
                     PG      P     +P  PG G
Sbjct: 1160 PGPPGEKGKPGQDGIPGPAGQKGEPGQPGFG 1190



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 132/499 (26%), Positives = 170/499 (34%), Gaps = 124/499 (24%)

Query: 129  GPKSRAKGSPGPPPPVARATRKG----PGPSGLLPESWKPGMGGDPRGVGA-GDMASAGP 183
            GPK   +G PG P     + + G    PGP G      +PG+ G P   G  GDM   GP
Sbjct: 979  GPKGY-QGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGP 1037

Query: 184  EG--------SVPCYP--PPAPGEFPEAHSLHLSLLGV-------------NYPLSPGLF 220
            +G         VP  P  P  PG+  +     +S +G+              YP +PG+ 
Sbjct: 1038 QGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIK 1097

Query: 221  SYLG-PSLAAAAHVP----------FLASASPLLPPATAFPAVQP--PQRPTPAPRLYYP 267
              +G P L      P          F  +  P  P   + P   P  P  P P     +P
Sbjct: 1098 GSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHP 1157

Query: 268  LLLEHTLGLPAGKAALAKAPV-SPRSPSGTPA-PGLLKVPVPGL---------GPWPRV- 315
                   G P  K    +  +  P    G P  PG      PGL         G  P + 
Sbjct: 1158 ----GQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIP 1213

Query: 316  -TPRDPGQEGELE----RAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVML 370
              P  PG +GE         Q  P    S G  LE PK +P           P G     
Sbjct: 1214 GNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPG----------PQGPP--- 1260

Query: 371  WPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGG 430
                G  G    PGPEGP  L   G + G   + G+     L          G  GP  G
Sbjct: 1261 -GRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLK------GDQGPP-G 1312

Query: 431  LAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPA-KGPQALGEAWGRPEL 489
            L   P R  L  ++ +              P  P    V   P  KGP  +  + G PE 
Sbjct: 1313 LQGNPGRPGLNGMKGD--------------PGLP---GVPGFPGMKGPSGVPGSAG-PEG 1354

Query: 490  GPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLPLAAPDDPVIPGSGWGTCV 549
             P L  G P PPG+ GP      SG +   + D+   PPG+P   P    +PG       
Sbjct: 1355 EPGLI-GPPGPPGLPGP------SGQSIIIKGDAG--PPGIP-GQPGLKGLPG------- 1397

Query: 550  ATRSSQTPEAVCGLQSPQG 568
                 Q P+ + G   P G
Sbjct: 1398 ----PQGPQGLPGPTGPPG 1412



 Score = 54.7 bits (130), Expect = 2e-07
 Identities = 94/342 (27%), Positives = 121/342 (35%), Gaps = 67/342 (19%)

Query: 90   PDRPG-ESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRAKGSPGPPPPVARAT 148
            P  PG    PG  P G +     P    +  +   +  GG P     G PGPP    +  
Sbjct: 1118 PGLPGFPGTPG--PPGPKGISGPPGNPGLPGEPGPVGGGGHP-----GQPGPPGEKGKPG 1170

Query: 149  RKG-PGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCYP--PPAPGEFPEAHSLH 205
            + G PGP+G   E  +PG G +P   G   ++    +G +P  P  P  PG  P+     
Sbjct: 1171 QDGIPGPAGQKGEPGQPGFG-NPGPPGLPGLSGQKGDGGLPGIPGNPGLPG--PKGEPGF 1227

Query: 206  LSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAFPAVQPPQRPTPAPRLY 265
                GV  P  PG     GP+L      P      P  P  T F  +  P+ P       
Sbjct: 1228 HGFPGVQGP--PGPPGSPGPALEGPKGNPG-PQGPPGRPGPTGFQGLPGPEGPP------ 1278

Query: 266  YPLLLEHTLGLPAGKAALAKAPVSPRSPS--GTPA-------PGLLKVPV-PGLG----- 310
                     GLP G   +     +P  P   G P        PGL   P  PGL      
Sbjct: 1279 ---------GLP-GNGGIKGEKGNPGQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGD 1328

Query: 311  PWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVML 370
            P     P  PG +G       + P     L      P   P L         P+G S+++
Sbjct: 1329 PGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIG----PPGPPGLPG-------PSGQSIII 1377

Query: 371  WPEDGDPGGPET------PGPEGPLPLQ-PRGPVPGSPEHVG 405
              + G PG P        PGP+GP  L  P GP PG P   G
Sbjct: 1378 KGDAGPPGIPGQPGLKGLPGPQGPQGLPGPTGP-PGDPGRNG 1418



 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 109/448 (24%), Positives = 151/448 (33%), Gaps = 82/448 (18%)

Query: 135 KGSPGPP-------PPVARATRKG----------PGPSGLLPESWKPGMGGDPRGVGA-- 175
           +G PGPP       PP      KG          PG  G   +   PG+ GDP   G   
Sbjct: 266 RGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPG 325

Query: 176 --------GDMASAGPEGSVPCYPPPAPGEFPEAHSLHLSLLG-VNYPLSPGLFSYLG-P 225
                   GD    GP G V   P P  G       + +   G +  P  PG     G P
Sbjct: 326 RDGEKGQKGDTGPPGPPGLV--IPRPGTG-------ITIGEKGNIGLPGLPGEKGERGFP 376

Query: 226 SLAAAAHVPFLASASPLLPPAT-AFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALA 284
            +     +P    A+ + PP    FP  +  +     P +  P         P G     
Sbjct: 377 GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPG--------PPGLDGQP 428

Query: 285 KAP--VSPRSPSGTPAPGLLKVPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGS 342
            AP    P  P+G   P   ++  PG  P P  +P D G +GE              +G+
Sbjct: 429 GAPGLPGPPGPAGPHIPPSDEICEPG-PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGT 487

Query: 343 RLELPKASPSLTRFCSRSSLPTGSSVMLWP-EDGDPGGPETPGPEGPLPLQPRGP----V 397
            +  P   P L        LP     + +P + G+ G     GP+G LP  P  P     
Sbjct: 488 GISGPPGQPGLP------GLPGPPGSLGFPGQKGEKGQAGATGPKG-LPGIPGAPGAPGF 540

Query: 398 PGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQA 457
           PGS    G+ LT     +  ++   G+LG  G      L    G+           L   
Sbjct: 541 PGSKGEPGDILT-----FPGMKGDKGELGSPGAPGLPGLPGTPGQ---------DGLPGL 586

Query: 458 VRPPDAPLDLSVK--RAPAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGH 515
             P   P  ++ K  R P   P   G       +GP   G    PPG +G    Q  +G+
Sbjct: 587 PGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFG----PPGPVGEKGIQGVAGN 642

Query: 516 TTKCEADSSVPPPGLPLAAPDDPVIPGS 543
             +         PG  +  P  P +PG+
Sbjct: 643 PGQPGIPGPKGDPGQTITQPGKPGLPGN 670



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 117/457 (25%), Positives = 151/457 (33%), Gaps = 136/457 (29%)

Query: 129 GPKSRA--KGSPGPPPPVARATRKGPGPSGLLPESWKPGMGG-----DPRGVGA--GDMA 179
           GP+ +    G PGPP P  +  R  PG  G       PGM G      P+G+    G   
Sbjct: 72  GPRGQKGDDGIPGPPGP--KGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKG 129

Query: 180 SAGPEGSV-------PCYPPPAPGEFPEAHSLHLSLL-----GVNYPLSPGLFSYLGPSL 227
             G  GS        P  PP  PG   E  S+ +S L        YP  PG+    GP+ 
Sbjct: 130 ERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPT- 188

Query: 228 AAAAHVPFLASASPLLPPATAFPAVQPPQRP--TPAPRLYYPLLLEHTLGL--------- 276
                        P+ PP    P +  P  P   P P+    L  +   G          
Sbjct: 189 ---------GIPGPIGPPGP--PGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGP 237

Query: 277 --PAGKAALAKAPVSPRSPSGTPA-PGLLKVPVPGLGPWPRVTPRDPGQEGELERAAQSD 333
             P G+ +  K P+      G    PG    P P   P  R  P  PG E + E+  Q +
Sbjct: 238 PGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGP---PGIRGPPGPPGGE-KGEKGEQGE 293

Query: 334 PRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQP 393
           P +R   G                               E+G PG P  PG  G      
Sbjct: 294 PGKRGKPGKD----------------------------GENGQPGIPGLPGDPG------ 319

Query: 394 RGPVPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQA 453
               PG P   GE   +  GD        G  GP G + PRP            +TI + 
Sbjct: 320 ---YPGEPGRDGEKGQK--GD-------TGPPGPPGLVIPRPGTG---------ITIGE- 357

Query: 454 LEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEPPG--MLGPAAPQP 511
            +  +  P  P +        KG +      G P        G P PPG  ++GP  P  
Sbjct: 358 -KGNIGLPGLPGE--------KGERGFPGIQGPP--------GLPGPPGAAVMGPPGPPG 400

Query: 512 FSGHTTKCEADSSVP------PPGLPLAAPDDPVIPG 542
           F G   + + D   P      PPGL    P  P +PG
Sbjct: 401 FPGERGQ-KGDEGPPGISIPGPPGLD-GQPGAPGLPG 435



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 118/490 (24%), Positives = 154/490 (31%), Gaps = 93/490 (18%)

Query: 90  PDRPGESDPGRQPQGARPTGAA------PAPDLVVADIHSLHCGGGPKSRAK-------G 136
           P  PG      Q     P G        P   + + +  ++   G P  + +       G
Sbjct: 321 PGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQG 380

Query: 137 SPGPPPPVARATRKGPGPSGLLPESWK--------------PGMGGDPRGVG-AGDMASA 181
            PG P P   A    PGP G   E  +              PG+ G P   G  G    A
Sbjct: 381 PPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPA 440

Query: 182 GPE---GSVPCYP-PPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLA 237
           GP        C P PP P   P    L     GV        F+ +G  ++     P L 
Sbjct: 441 GPHIPPSDEICEPGPPGPPGSPGDKGLQ-GEQGVKGDKGDTCFNCIGTGISGPPGQPGLP 499

Query: 238 SASPLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTP 297
              P  P +  FP  +  +    A               P G   +  AP +P  P    
Sbjct: 500 GL-PGPPGSLGFPGQKGEKGQAGATG-------------PKGLPGIPGAPGAPGFPGSKG 545

Query: 298 APG-LLKVP----------VPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLEL 346
            PG +L  P           PG    P + P  PGQ+G                   L  
Sbjct: 546 EPGDILTFPGMKGDKGELGSPGAPGLPGL-PGTPGQDGL----------------PGLPG 588

Query: 347 PKASPSLTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGE 406
           PK  P    F      P    +   P +  P GP   GP GP+  +    V G+P   G 
Sbjct: 589 PKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPG- 647

Query: 407 DLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLD 466
            +    GD  +   + G+     GL   P R+  G +    L     L      P  P  
Sbjct: 648 -IPGPKGDPGQTITQPGK----PGLPGNPGRD--GDVG---LPGDPGLPGQPGLPGIPGS 697

Query: 467 LSVKRAPAKGPQALGEAWGRPEL-GPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSV 525
                 P  G        G P + GP    GTP   G+ GP  P  F G   K E   ++
Sbjct: 698 KGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG--PKGEPGFAL 755

Query: 526 P----PPGLP 531
           P    PPGLP
Sbjct: 756 PGPPGPPGLP 765



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 113/443 (25%), Positives = 136/443 (30%), Gaps = 84/443 (18%)

Query: 136  GSPGPPPPVARATRKG-PGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEG-----SVPC 189
            G PG P    R    G PG  GL  +   PG+ G     G   +   GP G      +P 
Sbjct: 663  GKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIP- 721

Query: 190  YPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAF 249
             PP APG            +G+  P  PG   + GP         F     P  P    F
Sbjct: 722  GPPGAPGT--------PGRIGLEGP--PGPPGFPGPK----GEPGFALPGPPGPPGLPGF 767

Query: 250  PAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALA-KAPVSPRSPSGTPAPGLLKVPVPG 308
                 P+     P    P       GLP  K  +       P  P G P  G+   P P 
Sbjct: 768  KGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPP 827

Query: 309  LGPWPRVTP---------RDPGQEG------ELERAAQSDPRRRLSLGSRLELPKASPSL 353
              P P   P          DPG  G        ER +   P     +G     P  SP L
Sbjct: 828  GIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIG-----PPGSPGL 882

Query: 354  TRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVG----EDLT 409
                  S  P           G+ G    PGP GPL +  R  VPG     G      L 
Sbjct: 883  PGKAGASGFP--------GTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLP 934

Query: 410  RALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSV 469
               G+    +   G  GP G + P  L  +  K                  P  P    V
Sbjct: 935  GPTGEKGS-KGEPGLPGPPGPMDPNLLGSKGEK----------------GEPGLPGIPGV 977

Query: 470  KRAPAKGPQALGEAWGRPEL----------GPVLTGGTPEPPGMLGPAAPQPFSGHTTKC 519
              +  KG Q L    G+P L          GP    G P  PG++GP   +   G     
Sbjct: 978  --SGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFP 1035

Query: 520  EADSSVPPPGLPLAAPDDPVIPG 542
                   PPG P   P  P  PG
Sbjct: 1036 GPQGVEGPPG-PSGVPGQPGSPG 1057



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 100/370 (27%), Positives = 122/370 (32%), Gaps = 88/370 (23%)

Query: 78   RGSTTPRPHAPTPDRPGESDPGRQPQGARPTG--AAPAPDLVVADIHSLHCGGGPKSRAK 135
            +G + P  +   P  PG    G  P    P G    P  D +          G P     
Sbjct: 1133 KGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQK---GEPGQPGF 1189

Query: 136  GSPGPPPPVARATRKG-------------PGPSGLLPESWKPGMGGDPRGVGAGDMASAG 182
            G+PGPP     + +KG             PGP G       PG+ G P   G+   A  G
Sbjct: 1190 GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEG 1249

Query: 183  PEGSV-PCYPPPAPG----------EFPEAHSLHLSLLGVN----YPLSPGLFSYLG--- 224
            P+G+  P  PP  PG          E P     +  + G       P  PGL    G   
Sbjct: 1250 PKGNPGPQGPPGRPGPTGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQG 1309

Query: 225  -PSLAAAAHVPFL--ASASPLLPPATAFPAVQPPQR------PTPAPRLYYPLLLEHTLG 275
             P L      P L      P LP    FP ++ P        P   P L  P       G
Sbjct: 1310 PPGLQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPG 1369

Query: 276  LPAGKAALAKAPVSPRSPSGTPAPGLLKVPVP----GLGPWPRVTPRDPGQEGELERAAQ 331
             P+G++ + K    P    G P  GL  +P P    GL P P   P DPG+ G       
Sbjct: 1370 -PSGQSIIIKGDAGPPGIPGQP--GLKGLPGPQGPQGL-PGPTGPPGDPGRNG----LPG 1421

Query: 332  SDPRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPL 391
             D       G R    K  P L                     G PG     GP GP  L
Sbjct: 1422 FD-----GAGGR----KGDPGLP--------------------GQPGTRGLDGPPGPDGL 1452

Query: 392  Q-PRGPVPGS 400
            Q P GP PG+
Sbjct: 1453 QGPPGP-PGT 1461



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 125/483 (25%), Positives = 152/483 (31%), Gaps = 105/483 (21%)

Query: 128 GGPKSRAKGSPGPPPPVARATRKG---------PGPSGLLPESWKPGMGGDPRGVG---- 174
           G P +   G PGPP       +KG         PGP GL  +   PG+ G P   G    
Sbjct: 386 GPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIP 445

Query: 175 -AGDMASAGPEGSVPCYPPPAPGEFP---------EAHSLHLSLLGVNY---PLSPGLFS 221
            + ++   GP G     PP +PG+           +      + +G      P  PGL  
Sbjct: 446 PSDEICEPGPPG-----PPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPG 500

Query: 222 YLGP--SLA----------AAAHVPFLASASPLLPPATAFPAVQPPQRPTPAPRLYYPLL 269
             GP  SL           A A  P      P  P A  FP      +  P   L +P  
Sbjct: 501 LPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPG----SKGEPGDILTFP-- 554

Query: 270 LEHTLGLPAGKAALAK--APVSPRSPSGTPAPGLLKVPVPGLGPW------PRVTPRDPG 321
                G+   K  L    AP  P  P      GL  +P P   P        R  P +PG
Sbjct: 555 -----GMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPG 609

Query: 322 QEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLP--TGSSVMLWPEDGDPGG 379
             G         P      G   E  K    +     +  +P   G       + G PG 
Sbjct: 610 LPGLPGNIGPMGPPGFGPPGPVGE--KGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGL 667

Query: 380 PETPGPEGP--LPLQPRGP----VPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAP 433
           P  PG +G   LP  P  P    +PG P   GE     +G    +    G  G  G   P
Sbjct: 668 PGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIG----LPGPPGPKGFPGIPGP 723

Query: 434 RPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPA------KGPQALGEAWGRP 487
                  G+I LE             PP  P     K  P        GP  L    G  
Sbjct: 724 PGAPGTPGRIGLE------------GPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKG-- 769

Query: 488 ELGPVLTGGTPEPPGMLG----PAAPQPFSGHTTKCEADSSVPPPGLP----LAAPDDPV 539
            LGP    G P PPG  G       P P  G          + PPGLP       P  P 
Sbjct: 770 ALGPKGDRGFPGPPGPPGRTGLDGLPGP-KGDVGPNGQPGPMGPPGLPGIGVQGPPGPPG 828

Query: 540 IPG 542
           IPG
Sbjct: 829 IPG 831


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score = 59.3 bits (142), Expect = 9e-09
 Identities = 137/511 (26%), Positives = 172/511 (33%), Gaps = 95/511 (18%)

Query: 85   PHAP-TPDRPGESDPGRQPQGARPTG----AAPAPDLVVADIHSLHCGGGPKSRAKGSPG 139
            P AP TP R G   P   P    P G    A P P      +       GPK   +G PG
Sbjct: 724  PGAPGTPGRIGLEGPPGPPGFPGPKGEPGFALPGPP-GPPGLPGFKGALGPKGD-RGFPG 781

Query: 140  PPPPVARATRKG-PGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCYPPPA---- 194
            PP P  R    G PGP G +  + +PG  G P   G G     GP G       P     
Sbjct: 782  PPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGI 841

Query: 195  PGEFPEAHSLHLSLLG----------------VNYPLSPGLFSYLGPSLAAAAHVPFLAS 238
            PGE  +     L + G                +  P SPGL     P  A A+  P    
Sbjct: 842  PGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGL-----PGKAGASGFPGTKG 896

Query: 239  ASPLL-PPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTP 297
               ++ PP    P   P +   P  +    L  +  L  P G+      P  P  P G  
Sbjct: 897  EMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLP-GPPGPM 955

Query: 298  APGLL----KVPVPGLGPWPRVT--------PRDPGQEGELERAAQSDPRRRLSLGSRLE 345
             P LL    +   PGL   P V+        P DPGQ G   +     P           
Sbjct: 956  DPNLLGSKGEKGEPGLPGIPGVSGPKGYQGLPGDPGQPGLSGQPGLPGPPG--------- 1006

Query: 346  LPKASPSLTRFCSRSSLPTGSSVMLWPED-----GDPGGPETPGPEGPLPLQPRGPVPGS 400
             PK +P L           G   ++ P       GD G P   G EG  P  P G VPG 
Sbjct: 1007 -PKGNPGL----------PGQPGLIGPPGLKGTIGDMGFPGPQGVEG--PPGPSG-VPGQ 1052

Query: 401  PEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRP 460
            P   G  L    GD  + +  +  +G  G   P+      G+  L     +  ++ +V  
Sbjct: 1053 PGSPG--LPGQKGD--KGDPGISSIGLPGLPGPK------GEPGLPGYPGNPGIKGSVGD 1102

Query: 461  PDAPLDLSVKRAP-AKGPQALGEAWGRP-ELGPVLTGGTPEPPGMLGPAAPQPFSGHTTK 518
            P  P    +   P AKG   L    G P   GP    G P  PG+ G   P    GH  +
Sbjct: 1103 PGLP---GLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHPGQ 1159

Query: 519  CEADSSVPPPGL-----PLAAPDDPVIPGSG 544
                     PG      P     +P  PG G
Sbjct: 1160 PGPPGEKGKPGQDGIPGPAGQKGEPGQPGFG 1190



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 133/499 (26%), Positives = 171/499 (34%), Gaps = 127/499 (25%)

Query: 129  GPKSRAKGSPGPPPPVARATRKG----PGPSGLLPESWKPGMGGDPRGVGA-GDMASAGP 183
            GPK   +G PG P     + + G    PGP G      +PG+ G P   G  GDM   GP
Sbjct: 979  GPKGY-QGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFPGP 1037

Query: 184  EG--------SVPCYP--PPAPGEFPEAHSLHLSLLGV-------------NYPLSPGLF 220
            +G         VP  P  P  PG+  +     +S +G+              YP +PG+ 
Sbjct: 1038 QGVEGPPGPSGVPGQPGSPGLPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIK 1097

Query: 221  SYLG-PSLAAAAHVP----------FLASASPLLPPATAFPAVQP--PQRPTPAPRLYYP 267
              +G P L      P          F  +  P  P   + P   P  P  P P     +P
Sbjct: 1098 GSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHP 1157

Query: 268  LLLEHTLGLPAGKAALAKAPV-SPRSPSGTPA-PGLLKVPVPGL---------GPWPRV- 315
                   G P  K    +  +  P    G P  PG      PGL         G  P + 
Sbjct: 1158 ----GQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGDGGLPGIP 1213

Query: 316  -TPRDPGQEGELE----RAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVML 370
              P  PG +GE         Q  P    S G  LE PK +P           P G     
Sbjct: 1214 GNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPG----------PQGPP--- 1260

Query: 371  WPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGG 430
                G PG    PGPEGP  L   G + G   + G+     L          G  GP  G
Sbjct: 1261 ----GRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLK------GDQGPP-G 1309

Query: 431  LAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPA-KGPQALGEAWGRPEL 489
            L   P R  L  ++ +              P  P    V   P  KGP  +  + G PE 
Sbjct: 1310 LQGNPGRPGLNGMKGD--------------PGLP---GVPGFPGMKGPSGVPGSAG-PEG 1351

Query: 490  GPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLPLAAPDDPVIPGSGWGTCV 549
             P L  G P PPG+ GP      SG +   + D+   PPG+P   P    +PG       
Sbjct: 1352 EPGLI-GPPGPPGLPGP------SGQSIIIKGDAG--PPGIP-GQPGLKGLPG------- 1394

Query: 550  ATRSSQTPEAVCGLQSPQG 568
                 Q P+ + G   P G
Sbjct: 1395 ----PQGPQGLPGPTGPPG 1409



 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 109/448 (24%), Positives = 151/448 (33%), Gaps = 82/448 (18%)

Query: 135 KGSPGPP-------PPVARATRKG----------PGPSGLLPESWKPGMGGDPRGVGA-- 175
           +G PGPP       PP      KG          PG  G   +   PG+ GDP   G   
Sbjct: 266 RGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRGKPGKDGENGQPGIPGLPGDPGYPGEPG 325

Query: 176 --------GDMASAGPEGSVPCYPPPAPGEFPEAHSLHLSLLG-VNYPLSPGLFSYLG-P 225
                   GD    GP G V   P P  G       + +   G +  P  PG     G P
Sbjct: 326 RDGEKGQKGDTGPPGPPGLV--IPRPGTG-------ITIGEKGNIGLPGLPGEKGERGFP 376

Query: 226 SLAAAAHVPFLASASPLLPPAT-AFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALA 284
            +     +P    A+ + PP    FP  +  +     P +  P         P G     
Sbjct: 377 GIQGPPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPG--------PPGLDGQP 428

Query: 285 KAP--VSPRSPSGTPAPGLLKVPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGS 342
            AP    P  P+G   P   ++  PG  P P  +P D G +GE              +G+
Sbjct: 429 GAPGLPGPPGPAGPHIPPSDEICEPG-PPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGT 487

Query: 343 RLELPKASPSLTRFCSRSSLPTGSSVMLWP-EDGDPGGPETPGPEGPLPLQPRGP----V 397
            +  P   P L        LP     + +P + G+ G     GP+G LP  P  P     
Sbjct: 488 GISGPPGQPGLP------GLPGPPGSLGFPGQKGEKGQAGATGPKG-LPGIPGAPGAPGF 540

Query: 398 PGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQA 457
           PGS    G+ LT     +  ++   G+LG  G      L    G+           L   
Sbjct: 541 PGSKGEPGDILT-----FPGMKGDKGELGSPGAPGLPGLPGTPGQ---------DGLPGL 586

Query: 458 VRPPDAPLDLSVK--RAPAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGH 515
             P   P  ++ K  R P   P   G       +GP   G    PPG +G    Q  +G+
Sbjct: 587 PGPKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFG----PPGPVGEKGIQGVAGN 642

Query: 516 TTKCEADSSVPPPGLPLAAPDDPVIPGS 543
             +         PG  +  P  P +PG+
Sbjct: 643 PGQPGIPGPKGDPGQTITQPGKPGLPGN 670



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 117/457 (25%), Positives = 151/457 (33%), Gaps = 136/457 (29%)

Query: 129 GPKSRA--KGSPGPPPPVARATRKGPGPSGLLPESWKPGMGG-----DPRGVGA--GDMA 179
           GP+ +    G PGPP P  +  R  PG  G       PGM G      P+G+    G   
Sbjct: 72  GPRGQKGDDGIPGPPGP--KGIRGPPGLPGFPGTPGLPGMPGHDGAPGPQGIPGCNGTKG 129

Query: 180 SAGPEGSV-------PCYPPPAPGEFPEAHSLHLSLL-----GVNYPLSPGLFSYLGPSL 227
             G  GS        P  PP  PG   E  S+ +S L        YP  PG+    GP+ 
Sbjct: 130 ERGFPGSPGFPGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPT- 188

Query: 228 AAAAHVPFLASASPLLPPATAFPAVQPPQRP--TPAPRLYYPLLLEHTLGL--------- 276
                        P+ PP    P +  P  P   P P+    L  +   G          
Sbjct: 189 ---------GIPGPIGPPGP--PGLMGPPGPPGLPGPKGNMGLNFQGPKGEKGEQGLQGP 237

Query: 277 --PAGKAALAKAPVSPRSPSGTPA-PGLLKVPVPGLGPWPRVTPRDPGQEGELERAAQSD 333
             P G+ +  K P+      G    PG    P P   P  R  P  PG E + E+  Q +
Sbjct: 238 PGPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGP---PGIRGPPGPPGGE-KGEKGEQGE 293

Query: 334 PRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQP 393
           P +R   G                               E+G PG P  PG  G      
Sbjct: 294 PGKRGKPGKD----------------------------GENGQPGIPGLPGDPG------ 319

Query: 394 RGPVPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQA 453
               PG P   GE   +  GD        G  GP G + PRP            +TI + 
Sbjct: 320 ---YPGEPGRDGEKGQK--GD-------TGPPGPPGLVIPRPGTG---------ITIGE- 357

Query: 454 LEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEPPG--MLGPAAPQP 511
            +  +  P  P +        KG +      G P        G P PPG  ++GP  P  
Sbjct: 358 -KGNIGLPGLPGE--------KGERGFPGIQGPP--------GLPGPPGAAVMGPPGPPG 400

Query: 512 FSGHTTKCEADSSVP------PPGLPLAAPDDPVIPG 542
           F G   + + D   P      PPGL    P  P +PG
Sbjct: 401 FPGERGQ-KGDEGPPGISIPGPPGLD-GQPGAPGLPG 435



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 118/490 (24%), Positives = 154/490 (31%), Gaps = 93/490 (18%)

Query: 90  PDRPGESDPGRQPQGARPTGAA------PAPDLVVADIHSLHCGGGPKSRAK-------G 136
           P  PG      Q     P G        P   + + +  ++   G P  + +       G
Sbjct: 321 PGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGITIGEKGNIGLPGLPGEKGERGFPGIQG 380

Query: 137 SPGPPPPVARATRKGPGPSGLLPESWK--------------PGMGGDPRGVG-AGDMASA 181
            PG P P   A    PGP G   E  +              PG+ G P   G  G    A
Sbjct: 381 PPGLPGPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPA 440

Query: 182 GPE---GSVPCYP-PPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLA 237
           GP        C P PP P   P    L     GV        F+ +G  ++     P L 
Sbjct: 441 GPHIPPSDEICEPGPPGPPGSPGDKGLQ-GEQGVKGDKGDTCFNCIGTGISGPPGQPGLP 499

Query: 238 SASPLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTP 297
              P  P +  FP  +  +    A               P G   +  AP +P  P    
Sbjct: 500 GL-PGPPGSLGFPGQKGEKGQAGATG-------------PKGLPGIPGAPGAPGFPGSKG 545

Query: 298 APG-LLKVP----------VPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLEL 346
            PG +L  P           PG    P + P  PGQ+G                   L  
Sbjct: 546 EPGDILTFPGMKGDKGELGSPGAPGLPGL-PGTPGQDGL----------------PGLPG 588

Query: 347 PKASPSLTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGE 406
           PK  P    F      P    +   P +  P GP   GP GP+  +    V G+P   G 
Sbjct: 589 PKGEPGGITFKGERGPPGNPGLPGLPGNIGPMGPPGFGPPGPVGEKGIQGVAGNPGQPG- 647

Query: 407 DLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLD 466
            +    GD  +   + G+     GL   P R+  G +    L     L      P  P  
Sbjct: 648 -IPGPKGDPGQTITQPGK----PGLPGNPGRD--GDVG---LPGDPGLPGQPGLPGIPGS 697

Query: 467 LSVKRAPAKGPQALGEAWGRPEL-GPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSV 525
                 P  G        G P + GP    GTP   G+ GP  P  F G   K E   ++
Sbjct: 698 KGEPGIPGIGLPGPPGPKGFPGIPGPPGAPGTPGRIGLEGPPGPPGFPG--PKGEPGFAL 755

Query: 526 P----PPGLP 531
           P    PPGLP
Sbjct: 756 PGPPGPPGLP 765



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 100/367 (27%), Positives = 122/367 (33%), Gaps = 85/367 (23%)

Query: 78   RGSTTPRPHAPTPDRPGESDPGRQPQGARPTG--AAPAPDLVVADIHSLHCGGGPKSRAK 135
            +G + P  +   P  PG    G  P    P G    P  D +          G P     
Sbjct: 1133 KGISGPPGNPGLPGEPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQK---GEPGQPGF 1189

Query: 136  GSPGPPPPVARATRKG-------------PGPSGLLPESWKPGMGGDPRGVGAGDMASAG 182
            G+PGPP     + +KG             PGP G       PG+ G P   G+   A  G
Sbjct: 1190 GNPGPPGLPGLSGQKGDGGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEG 1249

Query: 183  PEGSV-PCYPPPAPG-------EFPEAHSLHLSLLGVN----YPLSPGLFSYLG----PS 226
            P+G+  P  PP  PG       E P     +  + G       P  PGL    G    P 
Sbjct: 1250 PKGNPGPQGPPGRPGFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPPG 1309

Query: 227  LAAAAHVPFL--ASASPLLPPATAFPAVQPPQR------PTPAPRLYYPLLLEHTLGLPA 278
            L      P L      P LP    FP ++ P        P   P L  P       G P+
Sbjct: 1310 LQGNPGRPGLNGMKGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPG-PS 1368

Query: 279  GKAALAKAPVSPRSPSGTPAPGLLKVPVP----GLGPWPRVTPRDPGQEGELERAAQSDP 334
            G++ + K    P    G P  GL  +P P    GL P P   P DPG+ G        D 
Sbjct: 1369 GQSIIIKGDAGPPGIPGQP--GLKGLPGPQGPQGL-PGPTGPPGDPGRNG----LPGFD- 1420

Query: 335  RRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQ-P 393
                  G R    K  P L                     G PG     GP GP  LQ P
Sbjct: 1421 ----GAGGR----KGDPGLP--------------------GQPGTRGLDGPPGPDGLQGP 1452

Query: 394  RGPVPGS 400
             GP PG+
Sbjct: 1453 PGP-PGT 1458



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 113/443 (25%), Positives = 136/443 (30%), Gaps = 84/443 (18%)

Query: 136  GSPGPPPPVARATRKG-PGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEG-----SVPC 189
            G PG P    R    G PG  GL  +   PG+ G     G   +   GP G      +P 
Sbjct: 663  GKPGLPGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIP- 721

Query: 190  YPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAF 249
             PP APG            +G+  P  PG   + GP         F     P  P    F
Sbjct: 722  GPPGAPGT--------PGRIGLEGP--PGPPGFPGPK----GEPGFALPGPPGPPGLPGF 767

Query: 250  PAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALA-KAPVSPRSPSGTPAPGLLKVPVPG 308
                 P+     P    P       GLP  K  +       P  P G P  G+   P P 
Sbjct: 768  KGALGPKGDRGFPGPPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPP 827

Query: 309  LGPWPRVTP---------RDPGQEG------ELERAAQSDPRRRLSLGSRLELPKASPSL 353
              P P   P          DPG  G        ER +   P     +G     P  SP L
Sbjct: 828  GIPGPIGQPGLHGIPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIG-----PPGSPGL 882

Query: 354  TRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVG----EDLT 409
                  S  P           G+ G    PGP GPL +  R  VPG     G      L 
Sbjct: 883  PGKAGASGFP--------GTKGEMGMMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLP 934

Query: 410  RALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSV 469
               G+    +   G  GP G + P  L  +  K                  P  P    V
Sbjct: 935  GPTGEKGS-KGEPGLPGPPGPMDPNLLGSKGEK----------------GEPGLPGIPGV 977

Query: 470  KRAPAKGPQALGEAWGRPEL----------GPVLTGGTPEPPGMLGPAAPQPFSGHTTKC 519
              +  KG Q L    G+P L          GP    G P  PG++GP   +   G     
Sbjct: 978  --SGPKGYQGLPGDPGQPGLSGQPGLPGPPGPKGNPGLPGQPGLIGPPGLKGTIGDMGFP 1035

Query: 520  EADSSVPPPGLPLAAPDDPVIPG 542
                   PPG P   P  P  PG
Sbjct: 1036 GPQGVEGPPG-PSGVPGQPGSPG 1057



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 125/483 (25%), Positives = 152/483 (31%), Gaps = 105/483 (21%)

Query: 128 GGPKSRAKGSPGPPPPVARATRKG---------PGPSGLLPESWKPGMGGDPRGVG---- 174
           G P +   G PGPP       +KG         PGP GL  +   PG+ G P   G    
Sbjct: 386 GPPGAAVMGPPGPPGFPGERGQKGDEGPPGISIPGPPGLDGQPGAPGLPGPPGPAGPHIP 445

Query: 175 -AGDMASAGPEGSVPCYPPPAPGEFP---------EAHSLHLSLLGVNY---PLSPGLFS 221
            + ++   GP G     PP +PG+           +      + +G      P  PGL  
Sbjct: 446 PSDEICEPGPPG-----PPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPG 500

Query: 222 YLGP--SLA----------AAAHVPFLASASPLLPPATAFPAVQPPQRPTPAPRLYYPLL 269
             GP  SL           A A  P      P  P A  FP      +  P   L +P  
Sbjct: 501 LPGPPGSLGFPGQKGEKGQAGATGPKGLPGIPGAPGAPGFPG----SKGEPGDILTFP-- 554

Query: 270 LEHTLGLPAGKAALAK--APVSPRSPSGTPAPGLLKVPVPGLGPW------PRVTPRDPG 321
                G+   K  L    AP  P  P      GL  +P P   P        R  P +PG
Sbjct: 555 -----GMKGDKGELGSPGAPGLPGLPGTPGQDGLPGLPGPKGEPGGITFKGERGPPGNPG 609

Query: 322 QEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLP--TGSSVMLWPEDGDPGG 379
             G         P      G   E  K    +     +  +P   G       + G PG 
Sbjct: 610 LPGLPGNIGPMGPPGFGPPGPVGE--KGIQGVAGNPGQPGIPGPKGDPGQTITQPGKPGL 667

Query: 380 PETPGPEGP--LPLQPRGP----VPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAP 433
           P  PG +G   LP  P  P    +PG P   GE     +G    +    G  G  G   P
Sbjct: 668 PGNPGRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIG----LPGPPGPKGFPGIPGP 723

Query: 434 RPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPA------KGPQALGEAWGRP 487
                  G+I LE             PP  P     K  P        GP  L    G  
Sbjct: 724 PGAPGTPGRIGLE------------GPPGPPGFPGPKGEPGFALPGPPGPPGLPGFKG-- 769

Query: 488 ELGPVLTGGTPEPPGMLG----PAAPQPFSGHTTKCEADSSVPPPGLP----LAAPDDPV 539
            LGP    G P PPG  G       P P  G          + PPGLP       P  P 
Sbjct: 770 ALGPKGDRGFPGPPGPPGRTGLDGLPGP-KGDVGPNGQPGPMGPPGLPGIGVQGPPGPPG 828

Query: 540 IPG 542
           IPG
Sbjct: 829 IPG 831



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 95/363 (26%), Positives = 119/363 (32%), Gaps = 46/363 (12%)

Query: 90   PDRPG-ESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRAKGSPGPPPPVARAT 148
            P  PG    PG  P G +     P    +  +   +  GG P     G PGPP    +  
Sbjct: 1118 PGLPGFPGTPG--PPGPKGISGPPGNPGLPGEPGPVGGGGHP-----GQPGPPGEKGKPG 1170

Query: 149  RKG-PGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCYP--PPAPGEFPEAHSLH 205
            + G PGP+G   E  +PG G +P   G   ++    +G +P  P  P  PG  P+     
Sbjct: 1171 QDGIPGPAGQKGEPGQPGFG-NPGPPGLPGLSGQKGDGGLPGIPGNPGLPG--PKGEPGF 1227

Query: 206  LSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAFPAVQPPQRPTPAPRLY 265
                GV  P  PG     GP+L      P      P  PP    P  Q    P   P L 
Sbjct: 1228 HGFPGVQGP--PGPPGSPGPALEGPKGNP-----GPQGPPGR--PGFQGLPGPEGPPGLP 1278

Query: 266  YPLLLEHTLGLPAGKAALAKAP-----VSPRSPSGTPA----------PGLLKVP-VPGL 309
                ++   G P G+  L   P       P    G P           PGL  VP  PG+
Sbjct: 1279 GNGGIKGEKGNP-GQPGLPGLPGLKGDQGPPGLQGNPGRPGLNGMKGDPGLPGVPGFPGM 1337

Query: 310  GPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKAS---PSLTRFCSRSSLPTGS 366
               P   P   G EGE        P        +  + K     P +        LP   
Sbjct: 1338 -KGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSGQSIIIKGDAGPPGIPGQPGLKGLPGPQ 1396

Query: 367  SVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQLG 426
                 P  G  G P  PG  G       G   G P   G+  TR L      +   G  G
Sbjct: 1397 GPQGLP--GPTGPPGDPGRNGLPGFDGAGGRKGDPGLPGQPGTRGLDGPPGPDGLQGPPG 1454

Query: 427  PAG 429
            P G
Sbjct: 1455 PPG 1457


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 59.3 bits (142), Expect = 9e-09
 Identities = 114/494 (23%), Positives = 148/494 (29%), Gaps = 130/494 (26%)

Query: 62  KDSLSLLLDSPDWACRRGSTTPRPHAPTPDRPGESDP--GRQPQGARPTGAAPAPDLVVA 119
           ++S SL+  +P  A  +G   P+     P +P    P  G QPQG  P    P       
Sbjct: 26  EESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQ------ 79

Query: 120 DIHSLHCGGGPKSRAKGSP-GPPPPVARATRKGPGPSGLLPESWK--PGMGGDPRGVGAG 176
                    GP  +    P GPPPP      +GP P G    S +  PG    P   G  
Sbjct: 80  ---------GPPPQGGNKPQGPPPP---GKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGN 127

Query: 177 DMASAGPEGSVPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFL 236
                 P    P  PPP  G  P+         G   P  P      G + + ++  P  
Sbjct: 128 QPQGPPPPPGKPQGPPPQGGNKPQ---------GPPPPGKPQGPPPQGDNKSRSSRSP-- 176

Query: 237 ASASPLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGT 296
               P  PP       Q P  P   P+           G P       + P  P  P G 
Sbjct: 177 -PGKPQGPPPQGGNQPQGPPPPPGKPQ-----------GPPPQGGNKPQGPPPPGKPQGP 224

Query: 297 PA------------PGLLKVPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRL 344
           P             PG  + P P  G  P+  P  PG+         + P+     G   
Sbjct: 225 PPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK-- 282

Query: 345 ELPKASPSLTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHV 404
             P+  P      SRSS               PG P+ P P+G    Q   P PG P+  
Sbjct: 283 --PQGPPPQGGSKSRSSR------------SPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 328

Query: 405 GEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAP 464
                                 P GG  P                  Q      +P   P
Sbjct: 329 ---------------------PPQGGNKP------------------QGPPPPGKPQGPP 349

Query: 465 LDLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSS 524
                K   A+ P       G+P+  P   G  P+ P       P P  G+  + +A   
Sbjct: 350 PQGGSKSRSARSPP------GKPQGPPQQEGNNPQGP-------PPPAGGNPQQPQA--- 393

Query: 525 VPPPGLPLAAPDDP 538
            PP G P   P  P
Sbjct: 394 -PPAGQPQGPPRPP 406



 Score = 33.9 bits (76), Expect = 0.41
 Identities = 32/110 (29%), Positives = 41/110 (37%), Gaps = 18/110 (16%)

Query: 466 DLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSV 525
           D+S + +P+      G   G P  G     G P PPG   P  P P  G+    +     
Sbjct: 22  DVSQEESPSL---IAGNPQGAPPQGGNKPQGPPSPPGK--PQGPPPQGGN----QPQGPP 72

Query: 526 PPPGLPLA-------APDDPVIPGSGWGTCVATRSSQTPEAVCGLQSPQG 568
           PPPG P          P  P  PG   G       S++P +  G   PQG
Sbjct: 73  PPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPG--KPQG 120


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 129/511 (25%), Positives = 168/511 (32%), Gaps = 98/511 (19%)

Query: 79   GSTTPRPHAPTPDRPG-ESDPGRQ-PQGARPTGAAPAPDLVVADIHSLHCGGGPKSRAKG 136
            GS  P+     P  PG +  PG+  P+G  PTG    P             G P  + +G
Sbjct: 735  GSPGPKGDKGEPGGPGADGVPGKDGPRG--PTGPIGPPGPA----------GQPGDKGEG 782

Query: 137  -SPGPP-------PPVARATRKGPGPSGLLPESWKPGMGGDPRGVG----AGDMASAGPE 184
             +PG P        P  R     PGP+G       PG  G+P G G     G+    GP 
Sbjct: 783  GAPGLPGIAGPRGSPGERGETGPPGPAGF---PGAPGQNGEPGGKGERGAPGEKGEGGPP 839

Query: 185  -------GSVPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLA 237
                   GS P  PP   G   E  S          P  PG   + G   A     P  +
Sbjct: 840  GVAGPPGGSGPAGPPGPQGVKGERGS----------PGGPGAAGFPG---ARGLPGPPGS 886

Query: 238  SASPLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSP--RSPSG 295
            + +P  P  +  P    P  P PA     P      +  P G A       SP  + P G
Sbjct: 887  NGNPGPPGPSGSPGKDGP--PGPAGNTGAP--GSPGVSGPKGDAGQPGEKGSPGAQGPPG 942

Query: 296  TPAP-------GLLKVPVPGLGPWPRVTPRDPGQEGELERAAQS---------DPRRRLS 339
             P P       G   +  P   P PR +P   G +GE  +   +          P+    
Sbjct: 943  APGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPG 1002

Query: 340  LGSRLELP--KASPSLTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPV 397
            L      P    +P       R   P G       E+G PG P  PG  G     P GPV
Sbjct: 1003 LAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDR--GENGSPGAPGAPGHPG-----PPGPV 1055

Query: 398  PGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQA 457
             G     G+         A      G  G  G   PR  + + G+     +  H+     
Sbjct: 1056 -GPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGN 1114

Query: 458  VRPPDAPLDLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEP------PGMLGPAAPQP 511
               P +P        PA    A+G        GPV   G P        PG +GP  P+ 
Sbjct: 1115 PGAPGSP-------GPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPR- 1166

Query: 512  FSGHTTKCEADSSVPPPGLPLAAPDDPVIPG 542
              G+  +  ++ S   PG P   P  P  PG
Sbjct: 1167 --GNRGERGSEGSPGHPGQP-GPPGPPGAPG 1194



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 110/417 (26%), Positives = 133/417 (31%), Gaps = 80/417 (19%)

Query: 136 GSPGPPPPVARATRKG-PGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCYPPPA 194
           G PGPP P   A   G PG  G +  +  PG  G P     G     GP+G      PP 
Sbjct: 330 GQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAP-----GQRGEPGPQGHAGAQGPPG 384

Query: 195 PGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAH-VPFL--ASASPLLPPATAFPA 251
           P     +      +     P +PGL    GP   A A+  P L   +  P    A   P 
Sbjct: 385 PPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPG 444

Query: 252 VQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPGLL-KVPVPGL- 309
            +  +     P            G+P  K    K   SP  P     PG   +   PG  
Sbjct: 445 PRGERGEAGIP------------GVPGAKGEDGKDG-SPGEPGANGLPGAAGERGAPGFR 491

Query: 310 GP-WPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSV 368
           GP  P   P + G  GE      + PR     G+  E             R  +P G  +
Sbjct: 492 GPAGPNGIPGEKGPAGERGAPGPAGPR-----GAAGEP-----------GRDGVPGGPGM 535

Query: 369 MLWPEDGDPGGPET---PGPEG-------PLPLQPRGP-----VPGSPEHVGEDLTRALG 413
              P  G PGGP +   PGP G       P P  P GP     V G P   G D      
Sbjct: 536 RGMP--GSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGND------ 587

Query: 414 DYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAP 473
                  + G+ G  GG  P+    + G          +   Q    P  P        P
Sbjct: 588 ---GAPGKNGERGGPGGPGPQGPPGKNG----------ETGPQGPPGPTGPGGDKGDTGP 634

Query: 474 AKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGL 530
             GPQ L    G    GP    G P  PG  G A      G      A     PPGL
Sbjct: 635 -PGPQGLQGLPGTG--GPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGL 688



 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 135/509 (26%), Positives = 153/509 (30%), Gaps = 87/509 (17%)

Query: 72  PDWACRRGSTTPRPHAPTPDRPGESDPGRQ---PQGARPTGAA--PAPDLVVADIHSLHC 126
           P  A  RG+   R  A     PGE  P  +   P  A P GAA  P  D V         
Sbjct: 479 PGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGM 538

Query: 127 GGGPKSRAK-GSPGPPPPVARATRKGP-GPSGLLPESWKPGMGGDP-----RGVGAGDMA 179
            G P      G PGPP     + R GP GPSG      +PG+ G P      G    +  
Sbjct: 539 PGSPGGPGSDGKPGPPGSQGESGRPGPPGPSG---PRGQPGVMGFPGPKGNDGAPGKNGE 595

Query: 180 SAGPEGSVPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASA 239
             GP G  P  PP   GE            G   P  P      GP        P     
Sbjct: 596 RGGPGGPGPQGPPGKNGE-----------TGPQGPPGP-----TGPGGDKGDTGPPGPQG 639

Query: 240 SPLLPPATAFPAVQ-PPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPA 298
              LP     P     P  P P      P       G P GK   A AP     P    A
Sbjct: 640 LQGLPGTGGPPGENGKPGEPGPKGDAGAP-------GAPGGKGD-AGAPGERGPPGLAGA 691

Query: 299 PGLLKVPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCS 358
           PGL      G GP        PG EG    A    P           +P     L     
Sbjct: 692 PGLR----GGAGP--------PGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGL----- 734

Query: 359 RSSLPTGSSVMLWPEDGDPGGPETPGPEGPL----PLQPRGPVPGSPEHVGE----DLTR 410
            S  P G       E G PG    PG +GP     P+ P GP  G P   GE     L  
Sbjct: 735 GSPGPKGDK----GEPGGPGADGVPGKDGPRGPTGPIGPPGPA-GQPGDKGEGGAPGLPG 789

Query: 411 ALGDYARVEQR--------------LGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQ 456
             G      +R               GQ G  GG   R    + G+     +        
Sbjct: 790 IAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSG 849

Query: 457 AVRPPDAPLDLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQ--PFSG 514
              PP  P  +  +R    GP A G    R   GP  + G P PPG  G       P   
Sbjct: 850 PAGPP-GPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPA 908

Query: 515 HTTKCEADSSVPPPGLPLAAPDDPVIPGS 543
             T       V  P      P +   PG+
Sbjct: 909 GNTGAPGSPGVSGPKGDAGQPGEKGSPGA 937



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 111/444 (25%), Positives = 144/444 (32%), Gaps = 94/444 (21%)

Query: 79   GSTTPRPHAPTPDRPGESDP---GRQP-----QGARPTGAAPAPDLVVADIHSLHCGGGP 130
            G   P  +   P  PG S P     QP      GA+    AP P L +A I       GP
Sbjct: 903  GPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGP-LGIAGITGARGLAGP 961

Query: 131  KSRAKGSPGPPPPVARATRKGPGPSGLLPESWKPGMGG--------DPRGVG--AGDMAS 180
                 G PGP        R  PGP G+  ES KPG  G         P+G+   AG    
Sbjct: 962  P----GMPGP--------RGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGE 1009

Query: 181  AGPEGSVPCYPPPAPGEFPEAHSLHLSLLGVN-YPLSPGLFSYLGPS--LAAAAHVPFLA 237
             G +G+      P     P          G N  P +PG   + GP   +  A       
Sbjct: 1010 PGRDGNPGSDGLPGRDGSPGGKGDR----GENGSPGAPGAPGHPGPPGPVGPAGKSGDRG 1065

Query: 238  SASPLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTP 297
             + P  P     PA          PR       E       G       P +P SP    
Sbjct: 1066 ESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAG 1125

Query: 298  APGLLKVPVPGLGPWPRVTPRDP-GQEGELERAAQ-SDPRRRLSLGSRLELPKASPSLTR 355
              G +  P P  GP   V P  P G++G          P  R + G R            
Sbjct: 1126 QQGAIGSPGPA-GPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGER------------ 1172

Query: 356  FCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDY 415
                     GS       +G PG P  PGP GP P  P GP  G    VG      +G  
Sbjct: 1173 ---------GS-------EGSPGHPGQPGPPGP-PGAP-GPCCGG---VGAAAIAGIGG- 1210

Query: 416  ARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAK 475
                ++ G   P  G  P   +    +I   L +++  +E  + P  +      ++ PA+
Sbjct: 1211 ----EKAGGFAPYYGDEPMDFKINTDEIMTSLKSVNGQIESLISPDGS------RKNPAR 1260

Query: 476  GPQAL---------GEAWGRPELG 490
              + L         GE W  P  G
Sbjct: 1261 NCRDLKFCHPELKSGEYWVDPNQG 1284



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 94/391 (24%), Positives = 119/391 (30%), Gaps = 84/391 (21%)

Query: 132 SRAKGSPGPPPPVARATRKGPGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCYP 191
           +R     GP  P     +  PGP G+   +  PG+ G P     G   S GP G     P
Sbjct: 96  TRPPNGQGPQGP-----KGDPGPPGIPGRNGDPGIPGQP-----GSPGSPGPPGICESCP 145

Query: 192 PPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAFPA 251
                  P+  S  +   GV      GL  Y GP+       P   S  P  P +  +  
Sbjct: 146 TGPQNYSPQYDSYDVKS-GVAVG---GLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQG 201

Query: 252 VQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKA-PVSPRSPSGTPA-PGLLKVPVPGL 309
             PP  P  A             G P    A+  + P      SG P  PG   +P P  
Sbjct: 202 --PPGEPGQAG----------PSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPG 249

Query: 310 GPWPRVTPRDPGQEGEL-------ERAAQSDPRRRLSLGSRLELPKASPSLTRFC----S 358
              P   P  PG +G         E+     P  +   G   E     P   R       
Sbjct: 250 IKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERG 309

Query: 359 RSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARV 418
           R  LP  +       DG  G    PGP GP         PGSP   GE            
Sbjct: 310 RPGLPGAAGAR--GNDGARGSDGQPGPPGP---PGTAGFPGSPGAKGE------------ 352

Query: 419 EQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQ 478
                 +GPAG         Q G+                     P   +  + P   P 
Sbjct: 353 ------VGPAGSPGSNGAPGQRGE-------------------PGPQGHAGAQGPPGPPG 387

Query: 479 ALGEAWGRPELGPVLTGGTPEPPGMLGPAAP 509
             G   G+ E+GP    G P  PG++G   P
Sbjct: 388 INGSPGGKGEMGP---AGIPGAPGLMGARGP 415



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 45/173 (26%), Positives = 59/173 (34%), Gaps = 40/173 (23%)

Query: 375 GDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPR 434
           G PG P +PGP G     P GP   SP++   D+   +     V    G  GPAG     
Sbjct: 127 GQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVA----VGGLAGYPGPAG----- 177

Query: 435 PLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRPELGPVLT 494
                                    PP  P        P   P + G      E G    
Sbjct: 178 -------------------------PPGPPGPPGTSGHPGS-PGSPGYQGPPGEPGQAGP 211

Query: 495 GGTPEPPGMLGPAAPQPFSGHTTK--CEADSSVP-PPGL--PLAAPDDPVIPG 542
            G P PPG +GP+ P    G + +     +  +P PPG+  P   P  P + G
Sbjct: 212 SGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKG 264



 Score = 39.3 bits (90), Expect = 0.010
 Identities = 101/435 (23%), Positives = 127/435 (29%), Gaps = 93/435 (21%)

Query: 86  HAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRAKGSPG----PP 141
           H  +P  PG   P  +P  A P+G    P  +     S   G   +S   G PG    P 
Sbjct: 190 HPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGP---SGPAGKDGESGRPGRPGERGLPG 246

Query: 142 PPVARATRKGPGPSGLLPESWKPGMGGDPRGVGA----GDMASAGPEGSV-PCYPPPAPG 196
           PP  +     PG  G+       G  G+    GA    G+    G  G+  P  P  APG
Sbjct: 247 PPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGENGLPGENGAPGPMGPRGAPG 306

Query: 197 EFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATA-FPAVQPP 255
           E                P  PG     G   A  +         P  PP TA FP     
Sbjct: 307 E-------------RGRPGLPGAAGARGNDGARGSD----GQPGPPGPPGTAGFP----- 344

Query: 256 QRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPGLLKVPVPGLGPWPRV 315
                              G P  K  +  A     SP    APG    P P      + 
Sbjct: 345 -------------------GSPGAKGEVGPA----GSPGSNGAPGQRGEPGPQGHAGAQG 381

Query: 316 TPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVMLWPEDG 375
            P  PG  G      +  P           +P A   +             +  L    G
Sbjct: 382 PPGPPGINGSPGGKGEMGP---------AGIPGAPGLMGARGPPGPAGANGAPGLRGGAG 432

Query: 376 DPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRP 435
           +PG     G  GP   +    +PG P   GED               G+ G  G      
Sbjct: 433 EPGKNGAKGEPGPRGERGEAGIPGVPGAKGED---------------GKDGSPGEPGANG 477

Query: 436 LREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRPELGPVLTG 495
           L    G          +      R P  P  +  ++ PA    A G A  R   G     
Sbjct: 478 LPGAAG----------ERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRD 527

Query: 496 GTPEPPGMLG-PAAP 509
           G P  PGM G P +P
Sbjct: 528 GVPGGPGMRGMPGSP 542


>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
           sapiens]
          Length = 483

 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 80/292 (27%), Positives = 108/292 (36%), Gaps = 43/292 (14%)

Query: 95  ESDPGRQPQG---ARPTGAAPAPDL---------VVADIHSLHCGGGPKSRAKGSPGPPP 142
           ES  G   +G   A   GA+  P L         V+         GG   +  GS  P P
Sbjct: 74  ESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRAPSP 133

Query: 143 PVARATRKGPGPSGLLPESWKPGMGGDPRGVGAGDMAS------AGPEGSVPCYPPPAPG 196
            +   T  GP    L+P +  P +G      GA   A       A P  + P  PPP P 
Sbjct: 134 RLPNKTISGP----LIPPA-SPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPP 188

Query: 197 EFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAA--AHVPFLASASPLLPPATAF--PAV 252
             P +  +   L+    PL+ G    + P +  A     P      P LPPA+     AV
Sbjct: 189 PLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAV 248

Query: 253 QPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAK---------APVSPRSP--SGTPAPGL 301
           +P   P   P +  PL L    G P  KA  A          AP  P  P  S +P   L
Sbjct: 249 KPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASL 308

Query: 302 LKVPVPGLGPW----PRVTPRDPGQEGELERA-AQSDPRRRLSLGSRLELPK 348
              P+PG+       P + P+ P  +   ++A AQ+ P      GS+  L K
Sbjct: 309 PAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQK 360



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 68/283 (24%), Positives = 81/283 (28%), Gaps = 60/283 (21%)

Query: 79  GSTTPRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRAKGSP 138
           GS  P P  P     G   P   P+    + A           H       P+      P
Sbjct: 127 GSRAPSPRLPNKTISGPLIPPASPRLGNTSEA-----------HGAARTAPPRPNVPAPP 175

Query: 139 GPPPPVARATRKGPGPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSVPCYPPPAP--- 195
            P PP        P PS       K  +   P  +  G++    P   VPC PPP P   
Sbjct: 176 PPTPPPPPPPLPPPLPSS---SPIKTPLVSPPGPLTKGNLPVVAPP--VPCAPPPPPPPP 230

Query: 196 ----------------GEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAH------- 232
                              P+   LHL  +    PL P    Y G     A+        
Sbjct: 231 PPTPPPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPC-GYPGLKAEPASPAQDAQEP 289

Query: 233 ------VPFLASASPLLP-PATAFPAVQ-----PPQRPTPAPRLYYPLLLEHTLGLPAGK 280
                 +P  AS SP    PA   P V      PP  P  +P    P        LPA  
Sbjct: 290 PAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPP 349

Query: 281 AALAKAPVSPRSPSGTPAPGLLKVPVPGLGPWPRVTPRDPGQE 323
           A     P   +   G P  G  K     L P P    R P  E
Sbjct: 350 APPGSQPFLQKKRHGRPGAGGGK-----LNPPPAPPARSPTTE 387



 Score = 36.2 bits (82), Expect = 0.083
 Identities = 65/249 (26%), Positives = 83/249 (33%), Gaps = 27/249 (10%)

Query: 293 PSGTPAPGLLKVPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPS 352
           P   P P  L  P P LG  P   P  P    +     ++DP+ R +L + ++       
Sbjct: 2   PVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRK 61

Query: 353 LTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRAL 412
           +T+   RS+    SS     E G  G   T G   P       P  G     G  + R  
Sbjct: 62  VTQINDRSAPQIESSKGTNKEGG--GSANTRGASTP-------PTLGDLFAGGFPVLRPA 112

Query: 413 GDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRA 472
           G       + GQ GP G  AP P        RL   TI   L     PP +P   +   A
Sbjct: 113 GQRDVAGGKTGQ-GP-GSRAPSP--------RLPNKTISGPL----IPPASPRLGNTSEA 158

Query: 473 PAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLPL 532
                 A   A  RP +        P PP  L P  P      T        +    LP+
Sbjct: 159 HG----AARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPV 214

Query: 533 AAPDDPVIP 541
            AP  P  P
Sbjct: 215 VAPPVPCAP 223



 Score = 33.9 bits (76), Expect = 0.41
 Identities = 55/211 (26%), Positives = 74/211 (35%), Gaps = 16/211 (7%)

Query: 321 GQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVMLWPEDGDPGGP 380
           G+ G+   +    PR      S   +P ASP L      +S   G++    P    P  P
Sbjct: 120 GKTGQGPGSRAPSPRLPNKTISGPLIPPASPRL----GNTSEAHGAARTAPPRPNVPAPP 175

Query: 381 ETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQL 440
               P  P PL P  P+P S   +   L    G   +    L  + P    AP P     
Sbjct: 176 PPTPPPPPPPLPP--PLPSSSP-IKTPLVSPPGPLTK--GNLPVVAPPVPCAPPPPPPPP 230

Query: 441 GKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEP 500
                 L       ++AV+P  APL L     P   P  L    G P  G      +P  
Sbjct: 231 PPTPPPLPPASVLSDKAVKPQLAPLHLP----PIPPPLPLLPPCGYP--GLKAEPASPAQ 284

Query: 501 PGMLGPAAPQPFSGHTTKCEADSSVPPPGLP 531
                PA P P   + + C   +S+P P LP
Sbjct: 285 DAQEPPAPPPPLPPYAS-CSPRASLPAPPLP 314


>gi|89142737 alpha 3 type IV collagen isoform 5 precursor [Homo
           sapiens]
          Length = 1424

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 116/446 (26%), Positives = 142/446 (31%), Gaps = 135/446 (30%)

Query: 135 KGSPGPPPPVARATRKGP-GPSGL--LPESWKPGMGGDPRGVGA----GDMASAGPE--- 184
           +G+PGPP P      +GP GP G+   P S +PG+ G P   G     G+    G +   
Sbjct: 356 EGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMG 415

Query: 185 --GSVPCY----------PPPAPGEF------PEAHSLHLSLLGVNYPLSPGLFSYLGPS 226
             GS  C           PP  PG+       P  H L        Y  SPG+    GP 
Sbjct: 416 TPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLP------GYLGSPGIPGVDGPK 469

Query: 227 LAAAAHVPFLASASPLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKA 286
                    L +  P +P     P +                 L    G+P G+   A  
Sbjct: 470 ----GEPGLLCTQCPYIPGPPGLPGLPG---------------LHGVKGIP-GRQGAAGL 509

Query: 287 PVSPRSPSGTPAPGLLKVPV----PGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGS 342
             SP SP  T  PG    P     PGL      T +  GQ G        DP  R   G 
Sbjct: 510 KGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVG-----VPGDPGLRGQPGR 564

Query: 343 R-LELPKASPSLTRFCS-RSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGS 400
           + L+    +P +      +  L            GDPG P +PGP GP      GP  G 
Sbjct: 565 KGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGP-QGE 623

Query: 401 PEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRP 460
           P   G             +   G  GP G   PR                          
Sbjct: 624 PGLQG------------TQGVPGAPGPPGEAGPRG------------------------- 646

Query: 461 PDAPLDLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCE 520
                +LSV   P  GP                  G P PPG  GP  P    G   KC 
Sbjct: 647 -----ELSVS-TPVPGPP-----------------GPPGPPGHPGPQGPPGIPGSLGKC- 682

Query: 521 ADSSVPPPGLPLAAPD-DPVIPGSGW 545
                  PGLP   PD +P IPG G+
Sbjct: 683 -----GDPGLP--GPDGEPGIPGIGF 701



 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 118/432 (27%), Positives = 148/432 (34%), Gaps = 94/432 (21%)

Query: 136 GSPGPPPPVARATRKG-------------PGPSGLLPESWKPGMGGDPRGVGAGDMASAG 182
           G PG P    +  RKG             PGP G L  S + G  G P     GD  S G
Sbjct: 551 GVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPP-----GDPGSPG 605

Query: 183 PEGSVPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGP--SLAAAAHVPFLASAS 240
             G  P  P   PG  P+         GV  P +PG     GP   L+ +  VP      
Sbjct: 606 SPG--PAGPAGPPGYGPQGEPGLQGTQGV--PGAPGPPGEAGPRGELSVSTPVP-----G 656

Query: 241 PLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPG 300
           P  PP        PP  P P              G P    +L K    P  P     PG
Sbjct: 657 PPGPPG-------PPGHPGPQ-------------GPPGIPGSLGKCG-DPGLPGPDGEPG 695

Query: 301 LLKVPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRS 360
                +PG+G      P  PG +G+     Q  P  + SLG   ++    P L     + 
Sbjct: 696 -----IPGIG-----FPGPPGPKGD-----QGFPGTKGSLGCPGKM--GEPGLP---GKP 735

Query: 361 SLPTGSSVMLWPEDGDPGGPETPG---------PEGPLPLQPRGPVPGSPEHVGEDLTRA 411
            LP        P    PGGP TPG           G + L     +PG+P + G D  R 
Sbjct: 736 GLPGAKGE---PAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPR- 791

Query: 412 LGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKR 471
            GD  +     G+ GP G     P   Q G   L  L   Q       P   P    + R
Sbjct: 792 -GDPGQPGPP-GEQGPPGRCIEGPRGAQ-GLPGLNGLKGQQGRRGKTGPKGDPGIPGLDR 848

Query: 472 APAKGPQAL-GEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGL 530
           +   G     G    + E+GP+   G P  PG+LGP       G         ++ PPG 
Sbjct: 849 SGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIG---MMGFPGAIGPPG- 904

Query: 531 PLAAPDDPVIPG 542
               P +P  PG
Sbjct: 905 ---PPGNPGTPG 913



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 114/418 (27%), Positives = 146/418 (34%), Gaps = 106/418 (25%)

Query: 135  KGSPGPPPPVARATRKGP-GPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSV-PCYPP 192
            KG PG     +  TR GP GP+G       PG+ GD      G+M   GP G + P  P 
Sbjct: 1053 KGEPG----YSEGTRPGPPGPTG------DPGLPGDMGK--KGEMGQPGPPGHLGPAGPE 1100

Query: 193  PAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAFPAV 252
             APG                 P SPGL    GP       + F      L PP    P  
Sbjct: 1101 GAPGS----------------PGSPGLPGKPGPH----GDLGFKGIKGLLGPPGIRGPPG 1140

Query: 253  QPPQRPTPAPRLYYPLLLEHTLGLPAGK---AALAKAPVSPR-SPSGTPAPGLLKVP-VP 307
             P    +P P           +  PAG+     L +AP  PR +P    A G    P  P
Sbjct: 1141 LPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFP 1200

Query: 308  GLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKAS-PSLTRFC----SRSSL 362
            GL          PG++G +  A    P           LP A  P  T       SR S 
Sbjct: 1201 GL----------PGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSP 1250

Query: 363  -------PTGSSVMLWPEDGDPGGPETPGPEGPL----PLQPRGPV--PGSPEHVGEDLT 409
                   P GS V+     GD G    PGP+GP      + P G +  PG+P   G    
Sbjct: 1251 GAPGPPGPPGSHVI--GIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGD 1308

Query: 410  RALGDYARVEQR------LGQLGPAGGLAPRP---LREQLGKIRLELLTIHQALEQAVRP 460
                 +  V+        LG +GP G + P+    +R   G +++       +L  +  P
Sbjct: 1309 PGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKII------SLPGSPGP 1362

Query: 461  PDAPLDLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTK 518
            P  P                GE   + E GP      P PPG LGP  P+   G   K
Sbjct: 1363 PGTP----------------GEPGMQGEPGP------PGPPGNLGPCGPRGKPGKDGK 1398



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 132/495 (26%), Positives = 158/495 (31%), Gaps = 137/495 (27%)

Query: 78  RGSTTPRPHAPTPDRPGESDPGRQP-------QGARPTGAAPAPDLVVADIHSLHCGGGP 130
           RG   P      P  PG S PG +        +G++     P  D  +    S  C G P
Sbjct: 368 RGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKD-AMGTPGSPGCAGSP 426

Query: 131 KSRAKGSPGPP-PPVARATRKGP-GPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGS-- 186
                GSPGPP PP     RKGP G  GL      PG  G P G+   D    GP+G   
Sbjct: 427 G--LPGSPGPPGPPGDIVFRKGPPGDHGL------PGYLGSP-GIPGVD----GPKGEPG 473

Query: 187 ---VPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLG-PSLAAAAHVPFLASASPL 242
                C   P P   P    LH  + G+  P   G     G P       +P      P 
Sbjct: 474 LLCTQCPYIPGPPGLPGLPGLH-GVKGI--PGRQGAAGLKGSPGSPGNTGLP----GFPG 526

Query: 243 LPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTP-APGL 301
            P A   P ++  +  T  P        E  +G+P G   L   P   +   G P  PG 
Sbjct: 527 FPGAQGDPGLKGEKGETLQP--------EGQVGVP-GDPGLRGQP-GRKGLDGIPGTPG- 575

Query: 302 LKVPVPGLGPWPRVTPRDPGQEGEL----ERAAQSDPRRRLSLGSRLELPKASPSLTRFC 357
               V GL          PG +GEL    E+  Q  P    S GS               
Sbjct: 576 ----VKGL----------PGPKGELALSGEKGDQGPPGDPGSPGS--------------- 606

Query: 358 SRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRA-LGDYA 416
                         P    P GP   GP+G   LQ    VPG+P   GE   R  L    
Sbjct: 607 --------------PGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652

Query: 417 RVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPA-K 475
            V    G  GP G   P+                         PP  P  L     P   
Sbjct: 653 PVPGPPGPPGPPGHPGPQ------------------------GPPGIPGSLGKCGDPGLP 688

Query: 476 GPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLPLAAP 535
           GP       G P +  +   G P PP   GP   Q F G          +  PGL    P
Sbjct: 689 GPD------GEPGIPGI---GFPGPP---GPKGDQGFPGTKGSLGCPGKMGEPGL----P 732

Query: 536 DDPVIPGSGWGTCVA 550
             P +PG+     VA
Sbjct: 733 GKPGLPGAKGEPAVA 747



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 94/370 (25%), Positives = 121/370 (32%), Gaps = 68/370 (18%)

Query: 81   TTPRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRAKGSPGP 140
            T P P  PT D     D G++ +  +P    P   L  A        G P S   G PG 
Sbjct: 1062 TRPGPPGPTGDPGLPGDMGKKGEMGQP---GPPGHLGPAGPEG--APGSPGS--PGLPGK 1114

Query: 141  PPPVARATRKGP----GPSGLLPESWKPGMGGDPRGVGA-------GDMASAGPEGSVPC 189
            P P      KG     GP G+      PG  G P  +G        G    AG +G    
Sbjct: 1115 PGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGL 1174

Query: 190  Y-PPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLG----------------PSLAAAAH 232
               PP P   P A           +P  PG    +G                P L  A  
Sbjct: 1175 LRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAII 1234

Query: 233  VPFLASASPLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRS 292
                 +  P  P +   P    P  P  +          H +G+   K ++      P+ 
Sbjct: 1235 PGQTGNRGP--PGSRGSPGAPGPPGPPGS----------HVIGIKGDKGSMGHP--GPKG 1280

Query: 293  PSGTPA----PGLLKVP-VPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLEL- 346
            P GT      PG L  P  PGL P PR  P   G  G   +  + +P    S+G    + 
Sbjct: 1281 PPGTAGDMGPPGRLGAPGTPGL-PGPRGDPGFQGFPGV--KGEKGNPGFLGSIGPPGPIG 1337

Query: 347  PKASPSLT------RFCSRSSLP----TGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGP 396
            PK  P +       +  S    P    T     +  E G PG P   GP GP     +  
Sbjct: 1338 PKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDG 1397

Query: 397  VPGSPEHVGE 406
             PG+P   GE
Sbjct: 1398 KPGTPGPAGE 1407



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 107/412 (25%), Positives = 135/412 (32%), Gaps = 53/412 (12%)

Query: 134  AKGSPGPPPPVARATRKGPGPSGLLPESWKPGMGGDPRGVGA-GDMASAGPEGSVPCYPP 192
            AKG P    P    T   PG  G   E  + G+ G P   G  G+    GP G      P
Sbjct: 740  AKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGP 799

Query: 193  PA----PGEFPEAHSLHLSLLGVN-YPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPAT 247
            P     PG   E       L G+N      G     GP       +P L  +    P  T
Sbjct: 800  PGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPK--GDPGIPGLDRSG--FPGET 855

Query: 248  AFPAVQPPQRPT-PAPRLYYPLLLEHTLGLPAGKAALAK----APVSPRSPSGTPA-PGL 301
              P +   Q    P  +  YP      LG P     +        + P  P G P  PG 
Sbjct: 856  GSPGIPGHQGEMGPLGQRGYPGN-PGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQ 914

Query: 302  LKVP-VPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRS 360
               P +PG+    R TP   G++G+      S+    +         K  P L  F    
Sbjct: 915  RGSPGIPGV-KGQRGTPGAKGEQGDKGNPGPSEISHVIG-------DKGEPGLKGFAGNP 966

Query: 361  SLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQ 420
                   V   P  G  G    PGP GP    PRG + GS  + GE   R       +  
Sbjct: 967  GEKGNRGVPGMP--GLKGLKGLPGPAGPPG--PRGDL-GSTGNPGEPGLRG------IPG 1015

Query: 421  RLGQLGPAGGLAPRPLREQLGKI-RLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQA 479
             +G +G  G    R      G+  R  L  IH        P  +         P   P  
Sbjct: 1016 SMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGL 1075

Query: 480  LGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLP 531
             G+   + E+G       P PPG LGPA P+          A  S   PGLP
Sbjct: 1076 PGDMGKKGEMGQ------PGPPGHLGPAGPE---------GAPGSPGSPGLP 1112



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 117/469 (24%), Positives = 147/469 (31%), Gaps = 114/469 (24%)

Query: 134 AKGSPGPPPPVARATRKGPGPSGLLPESWKPGMGGDPRGVG----AGDMASAGPEGSVPC 189
           AKG PG P          PGP GL      PG  G P   G     G M   GP+G +  
Sbjct: 169 AKGDPGLPG--------APGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHM-- 218

Query: 190 YPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAF 249
                 GE    H     + G+  P  PG                         PP T  
Sbjct: 219 ------GERVIGHKGERGVKGLTGP--PG-------------------------PPGTVI 245

Query: 250 PAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTP---------APG 300
             +  P   T               G    K A+ +    P  PSG P         APG
Sbjct: 246 VTLTGPDNRTDLK------------GEKGDKGAMGEP--GPPGPSGLPGESYGSEKGAPG 291

Query: 301 LLKVPVPGLG--PWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCS 358
                 PGL   P     P  PG EG   +  +  P      G + +     P   R   
Sbjct: 292 -----DPGLQGKPGKDGVPGFPGSEGV--KGNRGFPGLMGEDGIKGQKGDIGPPGFRG-- 342

Query: 359 RSSLPTGSSVMLWPEDGDPGGPETPGPEGPL-PLQPRGP--VPGSPEHVGEDLTRALGDY 415
               PT      + E GD G P  PGP G   P  P GP  VPGSP      L  A G +
Sbjct: 343 ----PT-EYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPG-W 396

Query: 416 ARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAK 475
             ++   G+ G       RP ++ +G            L  +  PP  P D+  ++ P  
Sbjct: 397 PGLKGSKGERG-------RPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGP-P 448

Query: 476 GPQALGEAWGRPEL----GPVLTGG--------TPEPPGMLGPAAPQPFSGHTTKCEADS 523
           G   L    G P +    GP    G         P PPG+ G        G   +  A  
Sbjct: 449 GDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAG 508

Query: 524 SVPPPGLP--LAAPDDPVIPGSGWGTCVATRSSQT--PEAVCGLQSPQG 568
               PG P     P  P  PG+     +     +T  PE   G+    G
Sbjct: 509 LKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPG 557



 Score = 37.0 bits (84), Expect = 0.049
 Identities = 48/156 (30%), Positives = 56/156 (35%), Gaps = 15/156 (9%)

Query: 373 EDGDPGGPETP------GPEG-PLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQL 425
           E G PG P +P      GPEG P P  P+G  PG P   G    R +          G  
Sbjct: 50  EKGFPGPPGSPGQKGFTGPEGLPGPQGPKG-FPGLPGLTGSKGVRGISGLPGFSGSPGLP 108

Query: 426 GPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSV---KRAPAKGPQALGE 482
           G  G   P  L    G    +       L   +  P  P    +   K APAK      +
Sbjct: 109 GTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELD 168

Query: 483 AWGRPEL----GPVLTGGTPEPPGMLGPAAPQPFSG 514
           A G P L    GP    G P  PG +GP  P  F G
Sbjct: 169 AKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFG 204



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 114/443 (25%), Positives = 144/443 (32%), Gaps = 106/443 (23%)

Query: 110 AAPAPD--LVVADIHSLHCGGGPKSRA-KGSPGPPPPVARATRKGP----GPSGLLPESW 162
           AAPA     V  D     C G    +  KG PGPP    +    GP    GP G      
Sbjct: 23  AAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPG 82

Query: 163 KPGMGGDPRGVGAGDMASAGPEGSVPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSY 222
            PG+ G  +GV  G     G  GS     P  PG     ++    L+GV     PG    
Sbjct: 83  LPGLTGS-KGV-RGISGLPGFSGS-----PGLPGT--PGNTGPYGLVGV-----PGCSGS 128

Query: 223 LGPSLAAAAHVPFLASASPLLPPATAFPAVQPP-----QRPTPAPRLYYPLLLEHTLGLP 277
            G                P LP    +P +        Q+  PA      L  +   GLP
Sbjct: 129 KGEQ------------GFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLP 176

Query: 278 A--GKAALAKAPVSPRSPSGTPAPGLLKVPVPGLGPWP-RVTPRDP-GQEGELERAAQSD 333
              G   L   P  P  P G P P       PG   +P  + PR P G  GE     + +
Sbjct: 177 GAPGPQGLPGPPGFP-GPVGPPGP-------PGFFGFPGAMGPRGPKGHMGERVIGHKGE 228

Query: 334 PRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGP--LPL 391
              +   G          +LT   +R+ L          E GD G    PGP GP  LP 
Sbjct: 229 RGVKGLTGPPGPPGTVIVTLTGPDNRTDLKG--------EKGDKGAMGEPGPPGPSGLPG 280

Query: 392 QPRGP---VPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELL 448
           +  G     PG P   G+     +  +   E   G  G  G +    ++ Q G I     
Sbjct: 281 ESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDI----- 335

Query: 449 TIHQALEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAA 508
                      PP             +GP    + +   E G     GTP PPG  G   
Sbjct: 336 ----------GPPG-----------FRGPTEYYDTY--QEKG---DEGTPGPPGPRGARG 369

Query: 509 PQPFSGHTTKCEADSSVPPPGLP 531
           PQ  SG            PPG+P
Sbjct: 370 PQGPSG------------PPGVP 380



 Score = 34.7 bits (78), Expect = 0.24
 Identities = 57/184 (30%), Positives = 66/184 (35%), Gaps = 54/184 (29%)

Query: 375 GDPGGPETPGPEGPLPLQPRGPVPGSPEHVGED----LTRALGDYARVEQRLGQLGPAGG 430
           G PG P TPG  GP  L     VPG     GE     L   LG Y  +    G  G  G 
Sbjct: 103 GSPGLPGTPGNTGPYGLV---GVPGCSGSKGEQGFPGLPGTLG-YPGIPGAAGLKGQKGA 158

Query: 431 LAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRPELG 490
               P +E+     +EL              DA  D  +  AP  GPQ L    G P  G
Sbjct: 159 ----PAKEE----DIEL--------------DAKGDPGLPGAP--GPQGLPGPPGFP--G 192

Query: 491 PVLTGGTPEPPGM------LGPAAP-----QPFSGHTTKCEADSSVPPPGLP------LA 533
           PV   G P PPG       +GP  P     +   GH  +        PPG P      L 
Sbjct: 193 PV---GPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLT 249

Query: 534 APDD 537
            PD+
Sbjct: 250 GPDN 253


>gi|89142735 alpha 3 type IV collagen isoform 4 precursor [Homo
           sapiens]
          Length = 1494

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 116/446 (26%), Positives = 142/446 (31%), Gaps = 135/446 (30%)

Query: 135 KGSPGPPPPVARATRKGP-GPSGL--LPESWKPGMGGDPRGVGA----GDMASAGPE--- 184
           +G+PGPP P      +GP GP G+   P S +PG+ G P   G     G+    G +   
Sbjct: 356 EGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMG 415

Query: 185 --GSVPCY----------PPPAPGEF------PEAHSLHLSLLGVNYPLSPGLFSYLGPS 226
             GS  C           PP  PG+       P  H L        Y  SPG+    GP 
Sbjct: 416 TPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLP------GYLGSPGIPGVDGPK 469

Query: 227 LAAAAHVPFLASASPLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKA 286
                    L +  P +P     P +                 L    G+P G+   A  
Sbjct: 470 ----GEPGLLCTQCPYIPGPPGLPGLPG---------------LHGVKGIP-GRQGAAGL 509

Query: 287 PVSPRSPSGTPAPGLLKVPV----PGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGS 342
             SP SP  T  PG    P     PGL      T +  GQ G        DP  R   G 
Sbjct: 510 KGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVG-----VPGDPGLRGQPGR 564

Query: 343 R-LELPKASPSLTRFCS-RSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGS 400
           + L+    +P +      +  L            GDPG P +PGP GP      GP  G 
Sbjct: 565 KGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGP-QGE 623

Query: 401 PEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRP 460
           P   G             +   G  GP G   PR                          
Sbjct: 624 PGLQG------------TQGVPGAPGPPGEAGPRG------------------------- 646

Query: 461 PDAPLDLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCE 520
                +LSV   P  GP                  G P PPG  GP  P    G   KC 
Sbjct: 647 -----ELSVS-TPVPGPP-----------------GPPGPPGHPGPQGPPGIPGSLGKC- 682

Query: 521 ADSSVPPPGLPLAAPD-DPVIPGSGW 545
                  PGLP   PD +P IPG G+
Sbjct: 683 -----GDPGLP--GPDGEPGIPGIGF 701



 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 118/432 (27%), Positives = 148/432 (34%), Gaps = 94/432 (21%)

Query: 136 GSPGPPPPVARATRKG-------------PGPSGLLPESWKPGMGGDPRGVGAGDMASAG 182
           G PG P    +  RKG             PGP G L  S + G  G P     GD  S G
Sbjct: 551 GVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPP-----GDPGSPG 605

Query: 183 PEGSVPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGP--SLAAAAHVPFLASAS 240
             G  P  P   PG  P+         GV  P +PG     GP   L+ +  VP      
Sbjct: 606 SPG--PAGPAGPPGYGPQGEPGLQGTQGV--PGAPGPPGEAGPRGELSVSTPVP-----G 656

Query: 241 PLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPG 300
           P  PP        PP  P P              G P    +L K    P  P     PG
Sbjct: 657 PPGPPG-------PPGHPGPQ-------------GPPGIPGSLGKCG-DPGLPGPDGEPG 695

Query: 301 LLKVPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRS 360
                +PG+G      P  PG +G+     Q  P  + SLG   ++    P L     + 
Sbjct: 696 -----IPGIG-----FPGPPGPKGD-----QGFPGTKGSLGCPGKM--GEPGLP---GKP 735

Query: 361 SLPTGSSVMLWPEDGDPGGPETPG---------PEGPLPLQPRGPVPGSPEHVGEDLTRA 411
            LP        P    PGGP TPG           G + L     +PG+P + G D  R 
Sbjct: 736 GLPGAKGE---PAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPR- 791

Query: 412 LGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKR 471
            GD  +     G+ GP G     P   Q G   L  L   Q       P   P    + R
Sbjct: 792 -GDPGQPGPP-GEQGPPGRCIEGPRGAQ-GLPGLNGLKGQQGRRGKTGPKGDPGIPGLDR 848

Query: 472 APAKGPQAL-GEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGL 530
           +   G     G    + E+GP+   G P  PG+LGP       G         ++ PPG 
Sbjct: 849 SGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIG---MMGFPGAIGPPG- 904

Query: 531 PLAAPDDPVIPG 542
               P +P  PG
Sbjct: 905 ---PPGNPGTPG 913



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 114/418 (27%), Positives = 146/418 (34%), Gaps = 106/418 (25%)

Query: 135  KGSPGPPPPVARATRKGP-GPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSV-PCYPP 192
            KG PG     +  TR GP GP+G       PG+ GD      G+M   GP G + P  P 
Sbjct: 1053 KGEPG----YSEGTRPGPPGPTG------DPGLPGDMGK--KGEMGQPGPPGHLGPAGPE 1100

Query: 193  PAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAFPAV 252
             APG                 P SPGL    GP       + F      L PP    P  
Sbjct: 1101 GAPGS----------------PGSPGLPGKPGPH----GDLGFKGIKGLLGPPGIRGPPG 1140

Query: 253  QPPQRPTPAPRLYYPLLLEHTLGLPAGK---AALAKAPVSPR-SPSGTPAPGLLKVP-VP 307
             P    +P P           +  PAG+     L +AP  PR +P    A G    P  P
Sbjct: 1141 LPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFP 1200

Query: 308  GLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKAS-PSLTRFC----SRSSL 362
            GL          PG++G +  A    P           LP A  P  T       SR S 
Sbjct: 1201 GL----------PGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSP 1250

Query: 363  -------PTGSSVMLWPEDGDPGGPETPGPEGPL----PLQPRGPV--PGSPEHVGEDLT 409
                   P GS V+     GD G    PGP+GP      + P G +  PG+P   G    
Sbjct: 1251 GAPGPPGPPGSHVI--GIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGD 1308

Query: 410  RALGDYARVEQR------LGQLGPAGGLAPRP---LREQLGKIRLELLTIHQALEQAVRP 460
                 +  V+        LG +GP G + P+    +R   G +++       +L  +  P
Sbjct: 1309 PGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKII------SLPGSPGP 1362

Query: 461  PDAPLDLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTK 518
            P  P                GE   + E GP      P PPG LGP  P+   G   K
Sbjct: 1363 PGTP----------------GEPGMQGEPGP------PGPPGNLGPCGPRGKPGKDGK 1398



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 132/495 (26%), Positives = 158/495 (31%), Gaps = 137/495 (27%)

Query: 78  RGSTTPRPHAPTPDRPGESDPGRQP-------QGARPTGAAPAPDLVVADIHSLHCGGGP 130
           RG   P      P  PG S PG +        +G++     P  D  +    S  C G P
Sbjct: 368 RGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKD-AMGTPGSPGCAGSP 426

Query: 131 KSRAKGSPGPP-PPVARATRKGP-GPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGS-- 186
                GSPGPP PP     RKGP G  GL      PG  G P G+   D    GP+G   
Sbjct: 427 G--LPGSPGPPGPPGDIVFRKGPPGDHGL------PGYLGSP-GIPGVD----GPKGEPG 473

Query: 187 ---VPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLG-PSLAAAAHVPFLASASPL 242
                C   P P   P    LH  + G+  P   G     G P       +P      P 
Sbjct: 474 LLCTQCPYIPGPPGLPGLPGLH-GVKGI--PGRQGAAGLKGSPGSPGNTGLP----GFPG 526

Query: 243 LPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTP-APGL 301
            P A   P ++  +  T  P        E  +G+P G   L   P   +   G P  PG 
Sbjct: 527 FPGAQGDPGLKGEKGETLQP--------EGQVGVP-GDPGLRGQP-GRKGLDGIPGTPG- 575

Query: 302 LKVPVPGLGPWPRVTPRDPGQEGEL----ERAAQSDPRRRLSLGSRLELPKASPSLTRFC 357
               V GL          PG +GEL    E+  Q  P    S GS               
Sbjct: 576 ----VKGL----------PGPKGELALSGEKGDQGPPGDPGSPGS--------------- 606

Query: 358 SRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRA-LGDYA 416
                         P    P GP   GP+G   LQ    VPG+P   GE   R  L    
Sbjct: 607 --------------PGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652

Query: 417 RVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPA-K 475
            V    G  GP G   P+                         PP  P  L     P   
Sbjct: 653 PVPGPPGPPGPPGHPGPQ------------------------GPPGIPGSLGKCGDPGLP 688

Query: 476 GPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLPLAAP 535
           GP       G P +  +   G P PP   GP   Q F G          +  PGL    P
Sbjct: 689 GPD------GEPGIPGI---GFPGPP---GPKGDQGFPGTKGSLGCPGKMGEPGL----P 732

Query: 536 DDPVIPGSGWGTCVA 550
             P +PG+     VA
Sbjct: 733 GKPGLPGAKGEPAVA 747



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 99/393 (25%), Positives = 128/393 (32%), Gaps = 77/393 (19%)

Query: 81   TTPRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRAKGSPGP 140
            T P P  PT D     D G++ +  +P    P   L  A        G P S   G PG 
Sbjct: 1062 TRPGPPGPTGDPGLPGDMGKKGEMGQP---GPPGHLGPAGPEG--APGSPGS--PGLPGK 1114

Query: 141  PPPVARATRKGP----GPSGLLPESWKPGMGGDPRGVGA-------GDMASAGPEGSVPC 189
            P P      KG     GP G+      PG  G P  +G        G    AG +G    
Sbjct: 1115 PGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGL 1174

Query: 190  Y-PPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLG----------------PSLAAAAH 232
               PP P   P A           +P  PG    +G                P L  A  
Sbjct: 1175 LRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAII 1234

Query: 233  VPFLASASPLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRS 292
                 +  P  P +   P    P  P  +          H +G+   K ++      P+ 
Sbjct: 1235 PGQTGNRGP--PGSRGSPGAPGPPGPPGS----------HVIGIKGDKGSMGHP--GPKG 1280

Query: 293  PSGTPA----PGLLKVP-VPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLEL- 346
            P GT      PG L  P  PGL P PR  P   G  G   +  + +P    S+G    + 
Sbjct: 1281 PPGTAGDMGPPGRLGAPGTPGL-PGPRGDPGFQGFPGV--KGEKGNPGFLGSIGPPGPIG 1337

Query: 347  PKASPSLT------RFCSRSSLP----TGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGP 396
            PK  P +       +  S    P    T     +  E G PG P   GP GP     +  
Sbjct: 1338 PKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDG 1397

Query: 397  VPGSPEHVGEDLTRALGDYARVEQRLGQLGPAG 429
             PG+P   GE   +            G+ GPAG
Sbjct: 1398 KPGTPGPAGEKGNKG---------SKGEPGPAG 1421



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 107/412 (25%), Positives = 135/412 (32%), Gaps = 53/412 (12%)

Query: 134  AKGSPGPPPPVARATRKGPGPSGLLPESWKPGMGGDPRGVGA-GDMASAGPEGSVPCYPP 192
            AKG P    P    T   PG  G   E  + G+ G P   G  G+    GP G      P
Sbjct: 740  AKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGP 799

Query: 193  PA----PGEFPEAHSLHLSLLGVN-YPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPAT 247
            P     PG   E       L G+N      G     GP       +P L  +    P  T
Sbjct: 800  PGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPK--GDPGIPGLDRSG--FPGET 855

Query: 248  AFPAVQPPQRPT-PAPRLYYPLLLEHTLGLPAGKAALAK----APVSPRSPSGTPA-PGL 301
              P +   Q    P  +  YP      LG P     +        + P  P G P  PG 
Sbjct: 856  GSPGIPGHQGEMGPLGQRGYPGN-PGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQ 914

Query: 302  LKVP-VPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRS 360
               P +PG+    R TP   G++G+      S+    +         K  P L  F    
Sbjct: 915  RGSPGIPGV-KGQRGTPGAKGEQGDKGNPGPSEISHVIG-------DKGEPGLKGFAGNP 966

Query: 361  SLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQ 420
                   V   P  G  G    PGP GP    PRG + GS  + GE   R       +  
Sbjct: 967  GEKGNRGVPGMP--GLKGLKGLPGPAGPPG--PRGDL-GSTGNPGEPGLRG------IPG 1015

Query: 421  RLGQLGPAGGLAPRPLREQLGKI-RLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQA 479
             +G +G  G    R      G+  R  L  IH        P  +         P   P  
Sbjct: 1016 SMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGL 1075

Query: 480  LGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLP 531
             G+   + E+G       P PPG LGPA P+          A  S   PGLP
Sbjct: 1076 PGDMGKKGEMGQ------PGPPGHLGPAGPE---------GAPGSPGSPGLP 1112



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 117/469 (24%), Positives = 147/469 (31%), Gaps = 114/469 (24%)

Query: 134 AKGSPGPPPPVARATRKGPGPSGLLPESWKPGMGGDPRGVG----AGDMASAGPEGSVPC 189
           AKG PG P          PGP GL      PG  G P   G     G M   GP+G +  
Sbjct: 169 AKGDPGLPG--------APGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHM-- 218

Query: 190 YPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAF 249
                 GE    H     + G+  P  PG                         PP T  
Sbjct: 219 ------GERVIGHKGERGVKGLTGP--PG-------------------------PPGTVI 245

Query: 250 PAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTP---------APG 300
             +  P   T               G    K A+ +    P  PSG P         APG
Sbjct: 246 VTLTGPDNRTDLK------------GEKGDKGAMGEP--GPPGPSGLPGESYGSEKGAPG 291

Query: 301 LLKVPVPGLG--PWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCS 358
                 PGL   P     P  PG EG   +  +  P      G + +     P   R   
Sbjct: 292 -----DPGLQGKPGKDGVPGFPGSEGV--KGNRGFPGLMGEDGIKGQKGDIGPPGFRG-- 342

Query: 359 RSSLPTGSSVMLWPEDGDPGGPETPGPEGPL-PLQPRGP--VPGSPEHVGEDLTRALGDY 415
               PT      + E GD G P  PGP G   P  P GP  VPGSP      L  A G +
Sbjct: 343 ----PT-EYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPG-W 396

Query: 416 ARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAK 475
             ++   G+ G       RP ++ +G            L  +  PP  P D+  ++ P  
Sbjct: 397 PGLKGSKGERG-------RPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGP-P 448

Query: 476 GPQALGEAWGRPEL----GPVLTGG--------TPEPPGMLGPAAPQPFSGHTTKCEADS 523
           G   L    G P +    GP    G         P PPG+ G        G   +  A  
Sbjct: 449 GDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAG 508

Query: 524 SVPPPGLP--LAAPDDPVIPGSGWGTCVATRSSQT--PEAVCGLQSPQG 568
               PG P     P  P  PG+     +     +T  PE   G+    G
Sbjct: 509 LKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPG 557



 Score = 37.0 bits (84), Expect = 0.049
 Identities = 48/156 (30%), Positives = 56/156 (35%), Gaps = 15/156 (9%)

Query: 373 EDGDPGGPETP------GPEG-PLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQL 425
           E G PG P +P      GPEG P P  P+G  PG P   G    R +          G  
Sbjct: 50  EKGFPGPPGSPGQKGFTGPEGLPGPQGPKG-FPGLPGLTGSKGVRGISGLPGFSGSPGLP 108

Query: 426 GPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSV---KRAPAKGPQALGE 482
           G  G   P  L    G    +       L   +  P  P    +   K APAK      +
Sbjct: 109 GTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELD 168

Query: 483 AWGRPEL----GPVLTGGTPEPPGMLGPAAPQPFSG 514
           A G P L    GP    G P  PG +GP  P  F G
Sbjct: 169 AKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFG 204



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 114/443 (25%), Positives = 144/443 (32%), Gaps = 106/443 (23%)

Query: 110 AAPAPD--LVVADIHSLHCGGGPKSRA-KGSPGPPPPVARATRKGP----GPSGLLPESW 162
           AAPA     V  D     C G    +  KG PGPP    +    GP    GP G      
Sbjct: 23  AAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPG 82

Query: 163 KPGMGGDPRGVGAGDMASAGPEGSVPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSY 222
            PG+ G  +GV  G     G  GS     P  PG     ++    L+GV     PG    
Sbjct: 83  LPGLTGS-KGV-RGISGLPGFSGS-----PGLPGT--PGNTGPYGLVGV-----PGCSGS 128

Query: 223 LGPSLAAAAHVPFLASASPLLPPATAFPAVQPP-----QRPTPAPRLYYPLLLEHTLGLP 277
            G                P LP    +P +        Q+  PA      L  +   GLP
Sbjct: 129 KGEQ------------GFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLP 176

Query: 278 A--GKAALAKAPVSPRSPSGTPAPGLLKVPVPGLGPWP-RVTPRDP-GQEGELERAAQSD 333
              G   L   P  P  P G P P       PG   +P  + PR P G  GE     + +
Sbjct: 177 GAPGPQGLPGPPGFP-GPVGPPGP-------PGFFGFPGAMGPRGPKGHMGERVIGHKGE 228

Query: 334 PRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGP--LPL 391
              +   G          +LT   +R+ L          E GD G    PGP GP  LP 
Sbjct: 229 RGVKGLTGPPGPPGTVIVTLTGPDNRTDLKG--------EKGDKGAMGEPGPPGPSGLPG 280

Query: 392 QPRGP---VPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELL 448
           +  G     PG P   G+     +  +   E   G  G  G +    ++ Q G I     
Sbjct: 281 ESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDI----- 335

Query: 449 TIHQALEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAA 508
                      PP             +GP    + +   E G     GTP PPG  G   
Sbjct: 336 ----------GPPG-----------FRGPTEYYDTY--QEKG---DEGTPGPPGPRGARG 369

Query: 509 PQPFSGHTTKCEADSSVPPPGLP 531
           PQ  SG            PPG+P
Sbjct: 370 PQGPSG------------PPGVP 380



 Score = 34.7 bits (78), Expect = 0.24
 Identities = 57/184 (30%), Positives = 66/184 (35%), Gaps = 54/184 (29%)

Query: 375 GDPGGPETPGPEGPLPLQPRGPVPGSPEHVGED----LTRALGDYARVEQRLGQLGPAGG 430
           G PG P TPG  GP  L     VPG     GE     L   LG Y  +    G  G  G 
Sbjct: 103 GSPGLPGTPGNTGPYGLV---GVPGCSGSKGEQGFPGLPGTLG-YPGIPGAAGLKGQKGA 158

Query: 431 LAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRPELG 490
               P +E+     +EL              DA  D  +  AP  GPQ L    G P  G
Sbjct: 159 ----PAKEE----DIEL--------------DAKGDPGLPGAP--GPQGLPGPPGFP--G 192

Query: 491 PVLTGGTPEPPGM------LGPAAP-----QPFSGHTTKCEADSSVPPPGLP------LA 533
           PV   G P PPG       +GP  P     +   GH  +        PPG P      L 
Sbjct: 193 PV---GPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLT 249

Query: 534 APDD 537
            PD+
Sbjct: 250 GPDN 253


>gi|89142733 alpha 3 type IV collagen isoform 2 precursor [Homo
           sapiens]
          Length = 1637

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 116/446 (26%), Positives = 142/446 (31%), Gaps = 135/446 (30%)

Query: 135 KGSPGPPPPVARATRKGP-GPSGL--LPESWKPGMGGDPRGVGA----GDMASAGPE--- 184
           +G+PGPP P      +GP GP G+   P S +PG+ G P   G     G+    G +   
Sbjct: 356 EGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMG 415

Query: 185 --GSVPCY----------PPPAPGEF------PEAHSLHLSLLGVNYPLSPGLFSYLGPS 226
             GS  C           PP  PG+       P  H L        Y  SPG+    GP 
Sbjct: 416 TPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLP------GYLGSPGIPGVDGPK 469

Query: 227 LAAAAHVPFLASASPLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKA 286
                    L +  P +P     P +                 L    G+P G+   A  
Sbjct: 470 ----GEPGLLCTQCPYIPGPPGLPGLPG---------------LHGVKGIP-GRQGAAGL 509

Query: 287 PVSPRSPSGTPAPGLLKVPV----PGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGS 342
             SP SP  T  PG    P     PGL      T +  GQ G        DP  R   G 
Sbjct: 510 KGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVG-----VPGDPGLRGQPGR 564

Query: 343 R-LELPKASPSLTRFCS-RSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGS 400
           + L+    +P +      +  L            GDPG P +PGP GP      GP  G 
Sbjct: 565 KGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGP-QGE 623

Query: 401 PEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRP 460
           P   G             +   G  GP G   PR                          
Sbjct: 624 PGLQG------------TQGVPGAPGPPGEAGPRG------------------------- 646

Query: 461 PDAPLDLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCE 520
                +LSV   P  GP                  G P PPG  GP  P    G   KC 
Sbjct: 647 -----ELSVS-TPVPGPP-----------------GPPGPPGHPGPQGPPGIPGSLGKC- 682

Query: 521 ADSSVPPPGLPLAAPD-DPVIPGSGW 545
                  PGLP   PD +P IPG G+
Sbjct: 683 -----GDPGLP--GPDGEPGIPGIGF 701



 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 118/432 (27%), Positives = 148/432 (34%), Gaps = 94/432 (21%)

Query: 136 GSPGPPPPVARATRKG-------------PGPSGLLPESWKPGMGGDPRGVGAGDMASAG 182
           G PG P    +  RKG             PGP G L  S + G  G P     GD  S G
Sbjct: 551 GVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPP-----GDPGSPG 605

Query: 183 PEGSVPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGP--SLAAAAHVPFLASAS 240
             G  P  P   PG  P+         GV  P +PG     GP   L+ +  VP      
Sbjct: 606 SPG--PAGPAGPPGYGPQGEPGLQGTQGV--PGAPGPPGEAGPRGELSVSTPVP-----G 656

Query: 241 PLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPG 300
           P  PP        PP  P P              G P    +L K    P  P     PG
Sbjct: 657 PPGPPG-------PPGHPGPQ-------------GPPGIPGSLGKCG-DPGLPGPDGEPG 695

Query: 301 LLKVPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRS 360
                +PG+G      P  PG +G+     Q  P  + SLG   ++    P L     + 
Sbjct: 696 -----IPGIG-----FPGPPGPKGD-----QGFPGTKGSLGCPGKM--GEPGLP---GKP 735

Query: 361 SLPTGSSVMLWPEDGDPGGPETPG---------PEGPLPLQPRGPVPGSPEHVGEDLTRA 411
            LP        P    PGGP TPG           G + L     +PG+P + G D  R 
Sbjct: 736 GLPGAKGE---PAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPR- 791

Query: 412 LGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKR 471
            GD  +     G+ GP G     P   Q G   L  L   Q       P   P    + R
Sbjct: 792 -GDPGQPGPP-GEQGPPGRCIEGPRGAQ-GLPGLNGLKGQQGRRGKTGPKGDPGIPGLDR 848

Query: 472 APAKGPQAL-GEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGL 530
           +   G     G    + E+GP+   G P  PG+LGP       G         ++ PPG 
Sbjct: 849 SGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIG---MMGFPGAIGPPG- 904

Query: 531 PLAAPDDPVIPG 542
               P +P  PG
Sbjct: 905 ---PPGNPGTPG 913



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 114/418 (27%), Positives = 146/418 (34%), Gaps = 106/418 (25%)

Query: 135  KGSPGPPPPVARATRKGP-GPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSV-PCYPP 192
            KG PG     +  TR GP GP+G       PG+ GD      G+M   GP G + P  P 
Sbjct: 1053 KGEPG----YSEGTRPGPPGPTG------DPGLPGDMGK--KGEMGQPGPPGHLGPAGPE 1100

Query: 193  PAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAFPAV 252
             APG                 P SPGL    GP       + F      L PP    P  
Sbjct: 1101 GAPGS----------------PGSPGLPGKPGPH----GDLGFKGIKGLLGPPGIRGPPG 1140

Query: 253  QPPQRPTPAPRLYYPLLLEHTLGLPAGK---AALAKAPVSPR-SPSGTPAPGLLKVP-VP 307
             P    +P P           +  PAG+     L +AP  PR +P    A G    P  P
Sbjct: 1141 LPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFP 1200

Query: 308  GLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKAS-PSLTRFC----SRSSL 362
            GL          PG++G +  A    P           LP A  P  T       SR S 
Sbjct: 1201 GL----------PGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSP 1250

Query: 363  -------PTGSSVMLWPEDGDPGGPETPGPEGPL----PLQPRGPV--PGSPEHVGEDLT 409
                   P GS V+     GD G    PGP+GP      + P G +  PG+P   G    
Sbjct: 1251 GAPGPPGPPGSHVI--GIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGD 1308

Query: 410  RALGDYARVEQR------LGQLGPAGGLAPRP---LREQLGKIRLELLTIHQALEQAVRP 460
                 +  V+        LG +GP G + P+    +R   G +++       +L  +  P
Sbjct: 1309 PGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKII------SLPGSPGP 1362

Query: 461  PDAPLDLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTK 518
            P  P                GE   + E GP      P PPG LGP  P+   G   K
Sbjct: 1363 PGTP----------------GEPGMQGEPGP------PGPPGNLGPCGPRGKPGKDGK 1398



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 132/495 (26%), Positives = 158/495 (31%), Gaps = 137/495 (27%)

Query: 78  RGSTTPRPHAPTPDRPGESDPGRQP-------QGARPTGAAPAPDLVVADIHSLHCGGGP 130
           RG   P      P  PG S PG +        +G++     P  D  +    S  C G P
Sbjct: 368 RGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKD-AMGTPGSPGCAGSP 426

Query: 131 KSRAKGSPGPP-PPVARATRKGP-GPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGS-- 186
                GSPGPP PP     RKGP G  GL      PG  G P G+   D    GP+G   
Sbjct: 427 G--LPGSPGPPGPPGDIVFRKGPPGDHGL------PGYLGSP-GIPGVD----GPKGEPG 473

Query: 187 ---VPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLG-PSLAAAAHVPFLASASPL 242
                C   P P   P    LH  + G+  P   G     G P       +P      P 
Sbjct: 474 LLCTQCPYIPGPPGLPGLPGLH-GVKGI--PGRQGAAGLKGSPGSPGNTGLP----GFPG 526

Query: 243 LPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTP-APGL 301
            P A   P ++  +  T  P        E  +G+P G   L   P   +   G P  PG 
Sbjct: 527 FPGAQGDPGLKGEKGETLQP--------EGQVGVP-GDPGLRGQP-GRKGLDGIPGTPG- 575

Query: 302 LKVPVPGLGPWPRVTPRDPGQEGEL----ERAAQSDPRRRLSLGSRLELPKASPSLTRFC 357
               V GL          PG +GEL    E+  Q  P    S GS               
Sbjct: 576 ----VKGL----------PGPKGELALSGEKGDQGPPGDPGSPGS--------------- 606

Query: 358 SRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRA-LGDYA 416
                         P    P GP   GP+G   LQ    VPG+P   GE   R  L    
Sbjct: 607 --------------PGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652

Query: 417 RVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPA-K 475
            V    G  GP G   P+                         PP  P  L     P   
Sbjct: 653 PVPGPPGPPGPPGHPGPQ------------------------GPPGIPGSLGKCGDPGLP 688

Query: 476 GPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLPLAAP 535
           GP       G P +  +   G P PP   GP   Q F G          +  PGL    P
Sbjct: 689 GPD------GEPGIPGI---GFPGPP---GPKGDQGFPGTKGSLGCPGKMGEPGL----P 732

Query: 536 DDPVIPGSGWGTCVA 550
             P +PG+     VA
Sbjct: 733 GKPGLPGAKGEPAVA 747



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 99/393 (25%), Positives = 128/393 (32%), Gaps = 77/393 (19%)

Query: 81   TTPRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRAKGSPGP 140
            T P P  PT D     D G++ +  +P    P   L  A        G P S   G PG 
Sbjct: 1062 TRPGPPGPTGDPGLPGDMGKKGEMGQP---GPPGHLGPAGPEG--APGSPGS--PGLPGK 1114

Query: 141  PPPVARATRKGP----GPSGLLPESWKPGMGGDPRGVGA-------GDMASAGPEGSVPC 189
            P P      KG     GP G+      PG  G P  +G        G    AG +G    
Sbjct: 1115 PGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGL 1174

Query: 190  Y-PPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLG----------------PSLAAAAH 232
               PP P   P A           +P  PG    +G                P L  A  
Sbjct: 1175 LRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAII 1234

Query: 233  VPFLASASPLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRS 292
                 +  P  P +   P    P  P  +          H +G+   K ++      P+ 
Sbjct: 1235 PGQTGNRGP--PGSRGSPGAPGPPGPPGS----------HVIGIKGDKGSMGHP--GPKG 1280

Query: 293  PSGTPA----PGLLKVP-VPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLEL- 346
            P GT      PG L  P  PGL P PR  P   G  G   +  + +P    S+G    + 
Sbjct: 1281 PPGTAGDMGPPGRLGAPGTPGL-PGPRGDPGFQGFPGV--KGEKGNPGFLGSIGPPGPIG 1337

Query: 347  PKASPSLT------RFCSRSSLP----TGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGP 396
            PK  P +       +  S    P    T     +  E G PG P   GP GP     +  
Sbjct: 1338 PKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDG 1397

Query: 397  VPGSPEHVGEDLTRALGDYARVEQRLGQLGPAG 429
             PG+P   GE   +            G+ GPAG
Sbjct: 1398 KPGTPGPAGEKGNKG---------SKGEPGPAG 1421



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 107/412 (25%), Positives = 135/412 (32%), Gaps = 53/412 (12%)

Query: 134  AKGSPGPPPPVARATRKGPGPSGLLPESWKPGMGGDPRGVGA-GDMASAGPEGSVPCYPP 192
            AKG P    P    T   PG  G   E  + G+ G P   G  G+    GP G      P
Sbjct: 740  AKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGP 799

Query: 193  PA----PGEFPEAHSLHLSLLGVN-YPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPAT 247
            P     PG   E       L G+N      G     GP       +P L  +    P  T
Sbjct: 800  PGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPK--GDPGIPGLDRSG--FPGET 855

Query: 248  AFPAVQPPQRPT-PAPRLYYPLLLEHTLGLPAGKAALAK----APVSPRSPSGTPA-PGL 301
              P +   Q    P  +  YP      LG P     +        + P  P G P  PG 
Sbjct: 856  GSPGIPGHQGEMGPLGQRGYPGN-PGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQ 914

Query: 302  LKVP-VPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRS 360
               P +PG+    R TP   G++G+      S+    +         K  P L  F    
Sbjct: 915  RGSPGIPGV-KGQRGTPGAKGEQGDKGNPGPSEISHVIG-------DKGEPGLKGFAGNP 966

Query: 361  SLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQ 420
                   V   P  G  G    PGP GP    PRG + GS  + GE   R       +  
Sbjct: 967  GEKGNRGVPGMP--GLKGLKGLPGPAGPPG--PRGDL-GSTGNPGEPGLRG------IPG 1015

Query: 421  RLGQLGPAGGLAPRPLREQLGKI-RLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQA 479
             +G +G  G    R      G+  R  L  IH        P  +         P   P  
Sbjct: 1016 SMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGL 1075

Query: 480  LGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLP 531
             G+   + E+G       P PPG LGPA P+          A  S   PGLP
Sbjct: 1076 PGDMGKKGEMGQ------PGPPGHLGPAGPE---------GAPGSPGSPGLP 1112



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 117/469 (24%), Positives = 147/469 (31%), Gaps = 114/469 (24%)

Query: 134 AKGSPGPPPPVARATRKGPGPSGLLPESWKPGMGGDPRGVG----AGDMASAGPEGSVPC 189
           AKG PG P          PGP GL      PG  G P   G     G M   GP+G +  
Sbjct: 169 AKGDPGLPG--------APGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHM-- 218

Query: 190 YPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAF 249
                 GE    H     + G+  P  PG                         PP T  
Sbjct: 219 ------GERVIGHKGERGVKGLTGP--PG-------------------------PPGTVI 245

Query: 250 PAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTP---------APG 300
             +  P   T               G    K A+ +    P  PSG P         APG
Sbjct: 246 VTLTGPDNRTDLK------------GEKGDKGAMGEP--GPPGPSGLPGESYGSEKGAPG 291

Query: 301 LLKVPVPGLG--PWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCS 358
                 PGL   P     P  PG EG   +  +  P      G + +     P   R   
Sbjct: 292 -----DPGLQGKPGKDGVPGFPGSEGV--KGNRGFPGLMGEDGIKGQKGDIGPPGFRG-- 342

Query: 359 RSSLPTGSSVMLWPEDGDPGGPETPGPEGPL-PLQPRGP--VPGSPEHVGEDLTRALGDY 415
               PT      + E GD G P  PGP G   P  P GP  VPGSP      L  A G +
Sbjct: 343 ----PT-EYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPG-W 396

Query: 416 ARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAK 475
             ++   G+ G       RP ++ +G            L  +  PP  P D+  ++ P  
Sbjct: 397 PGLKGSKGERG-------RPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGP-P 448

Query: 476 GPQALGEAWGRPEL----GPVLTGG--------TPEPPGMLGPAAPQPFSGHTTKCEADS 523
           G   L    G P +    GP    G         P PPG+ G        G   +  A  
Sbjct: 449 GDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAG 508

Query: 524 SVPPPGLP--LAAPDDPVIPGSGWGTCVATRSSQT--PEAVCGLQSPQG 568
               PG P     P  P  PG+     +     +T  PE   G+    G
Sbjct: 509 LKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPG 557



 Score = 37.0 bits (84), Expect = 0.049
 Identities = 48/156 (30%), Positives = 56/156 (35%), Gaps = 15/156 (9%)

Query: 373 EDGDPGGPETP------GPEG-PLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQL 425
           E G PG P +P      GPEG P P  P+G  PG P   G    R +          G  
Sbjct: 50  EKGFPGPPGSPGQKGFTGPEGLPGPQGPKG-FPGLPGLTGSKGVRGISGLPGFSGSPGLP 108

Query: 426 GPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSV---KRAPAKGPQALGE 482
           G  G   P  L    G    +       L   +  P  P    +   K APAK      +
Sbjct: 109 GTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELD 168

Query: 483 AWGRPEL----GPVLTGGTPEPPGMLGPAAPQPFSG 514
           A G P L    GP    G P  PG +GP  P  F G
Sbjct: 169 AKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFG 204



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 114/443 (25%), Positives = 144/443 (32%), Gaps = 106/443 (23%)

Query: 110 AAPAPD--LVVADIHSLHCGGGPKSRA-KGSPGPPPPVARATRKGP----GPSGLLPESW 162
           AAPA     V  D     C G    +  KG PGPP    +    GP    GP G      
Sbjct: 23  AAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPG 82

Query: 163 KPGMGGDPRGVGAGDMASAGPEGSVPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSY 222
            PG+ G  +GV  G     G  GS     P  PG     ++    L+GV     PG    
Sbjct: 83  LPGLTGS-KGV-RGISGLPGFSGS-----PGLPGT--PGNTGPYGLVGV-----PGCSGS 128

Query: 223 LGPSLAAAAHVPFLASASPLLPPATAFPAVQPP-----QRPTPAPRLYYPLLLEHTLGLP 277
            G                P LP    +P +        Q+  PA      L  +   GLP
Sbjct: 129 KGEQ------------GFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLP 176

Query: 278 A--GKAALAKAPVSPRSPSGTPAPGLLKVPVPGLGPWP-RVTPRDP-GQEGELERAAQSD 333
              G   L   P  P  P G P P       PG   +P  + PR P G  GE     + +
Sbjct: 177 GAPGPQGLPGPPGFP-GPVGPPGP-------PGFFGFPGAMGPRGPKGHMGERVIGHKGE 228

Query: 334 PRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGP--LPL 391
              +   G          +LT   +R+ L          E GD G    PGP GP  LP 
Sbjct: 229 RGVKGLTGPPGPPGTVIVTLTGPDNRTDLKG--------EKGDKGAMGEPGPPGPSGLPG 280

Query: 392 QPRGP---VPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELL 448
           +  G     PG P   G+     +  +   E   G  G  G +    ++ Q G I     
Sbjct: 281 ESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDI----- 335

Query: 449 TIHQALEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAA 508
                      PP             +GP    + +   E G     GTP PPG  G   
Sbjct: 336 ----------GPPG-----------FRGPTEYYDTY--QEKG---DEGTPGPPGPRGARG 369

Query: 509 PQPFSGHTTKCEADSSVPPPGLP 531
           PQ  SG            PPG+P
Sbjct: 370 PQGPSG------------PPGVP 380



 Score = 34.7 bits (78), Expect = 0.24
 Identities = 57/184 (30%), Positives = 66/184 (35%), Gaps = 54/184 (29%)

Query: 375 GDPGGPETPGPEGPLPLQPRGPVPGSPEHVGED----LTRALGDYARVEQRLGQLGPAGG 430
           G PG P TPG  GP  L     VPG     GE     L   LG Y  +    G  G  G 
Sbjct: 103 GSPGLPGTPGNTGPYGLV---GVPGCSGSKGEQGFPGLPGTLG-YPGIPGAAGLKGQKGA 158

Query: 431 LAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRPELG 490
               P +E+     +EL              DA  D  +  AP  GPQ L    G P  G
Sbjct: 159 ----PAKEE----DIEL--------------DAKGDPGLPGAP--GPQGLPGPPGFP--G 192

Query: 491 PVLTGGTPEPPGM------LGPAAP-----QPFSGHTTKCEADSSVPPPGLP------LA 533
           PV   G P PPG       +GP  P     +   GH  +        PPG P      L 
Sbjct: 193 PV---GPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLT 249

Query: 534 APDD 537
            PD+
Sbjct: 250 GPDN 253


>gi|89142730 alpha 3 type IV collagen isoform 1 precursor [Homo
           sapiens]
          Length = 1670

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 116/446 (26%), Positives = 142/446 (31%), Gaps = 135/446 (30%)

Query: 135 KGSPGPPPPVARATRKGP-GPSGL--LPESWKPGMGGDPRGVGA----GDMASAGPE--- 184
           +G+PGPP P      +GP GP G+   P S +PG+ G P   G     G+    G +   
Sbjct: 356 EGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKDAMG 415

Query: 185 --GSVPCY----------PPPAPGEF------PEAHSLHLSLLGVNYPLSPGLFSYLGPS 226
             GS  C           PP  PG+       P  H L        Y  SPG+    GP 
Sbjct: 416 TPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGPPGDHGLP------GYLGSPGIPGVDGPK 469

Query: 227 LAAAAHVPFLASASPLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKA 286
                    L +  P +P     P +                 L    G+P G+   A  
Sbjct: 470 ----GEPGLLCTQCPYIPGPPGLPGLPG---------------LHGVKGIP-GRQGAAGL 509

Query: 287 PVSPRSPSGTPAPGLLKVPV----PGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGS 342
             SP SP  T  PG    P     PGL      T +  GQ G        DP  R   G 
Sbjct: 510 KGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVG-----VPGDPGLRGQPGR 564

Query: 343 R-LELPKASPSLTRFCS-RSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGS 400
           + L+    +P +      +  L            GDPG P +PGP GP      GP  G 
Sbjct: 565 KGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPPGDPGSPGSPGPAGPAGPPGYGP-QGE 623

Query: 401 PEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRP 460
           P   G             +   G  GP G   PR                          
Sbjct: 624 PGLQG------------TQGVPGAPGPPGEAGPRG------------------------- 646

Query: 461 PDAPLDLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCE 520
                +LSV   P  GP                  G P PPG  GP  P    G   KC 
Sbjct: 647 -----ELSVS-TPVPGPP-----------------GPPGPPGHPGPQGPPGIPGSLGKC- 682

Query: 521 ADSSVPPPGLPLAAPD-DPVIPGSGW 545
                  PGLP   PD +P IPG G+
Sbjct: 683 -----GDPGLP--GPDGEPGIPGIGF 701



 Score = 57.0 bits (136), Expect = 5e-08
 Identities = 118/432 (27%), Positives = 148/432 (34%), Gaps = 94/432 (21%)

Query: 136 GSPGPPPPVARATRKG-------------PGPSGLLPESWKPGMGGDPRGVGAGDMASAG 182
           G PG P    +  RKG             PGP G L  S + G  G P     GD  S G
Sbjct: 551 GVPGDPGLRGQPGRKGLDGIPGTPGVKGLPGPKGELALSGEKGDQGPP-----GDPGSPG 605

Query: 183 PEGSVPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGP--SLAAAAHVPFLASAS 240
             G  P  P   PG  P+         GV  P +PG     GP   L+ +  VP      
Sbjct: 606 SPG--PAGPAGPPGYGPQGEPGLQGTQGV--PGAPGPPGEAGPRGELSVSTPVP-----G 656

Query: 241 PLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTPAPG 300
           P  PP        PP  P P              G P    +L K    P  P     PG
Sbjct: 657 PPGPPG-------PPGHPGPQ-------------GPPGIPGSLGKCG-DPGLPGPDGEPG 695

Query: 301 LLKVPVPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRS 360
                +PG+G      P  PG +G+     Q  P  + SLG   ++    P L     + 
Sbjct: 696 -----IPGIG-----FPGPPGPKGD-----QGFPGTKGSLGCPGKM--GEPGLP---GKP 735

Query: 361 SLPTGSSVMLWPEDGDPGGPETPG---------PEGPLPLQPRGPVPGSPEHVGEDLTRA 411
            LP        P    PGGP TPG           G + L     +PG+P + G D  R 
Sbjct: 736 GLPGAKGE---PAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPR- 791

Query: 412 LGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKR 471
            GD  +     G+ GP G     P   Q G   L  L   Q       P   P    + R
Sbjct: 792 -GDPGQPGPP-GEQGPPGRCIEGPRGAQ-GLPGLNGLKGQQGRRGKTGPKGDPGIPGLDR 848

Query: 472 APAKGPQAL-GEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGL 530
           +   G     G    + E+GP+   G P  PG+LGP       G         ++ PPG 
Sbjct: 849 SGFPGETGSPGIPGHQGEMGPLGQRGYPGNPGILGPPGEDGVIG---MMGFPGAIGPPG- 904

Query: 531 PLAAPDDPVIPG 542
               P +P  PG
Sbjct: 905 ---PPGNPGTPG 913



 Score = 51.2 bits (121), Expect = 3e-06
 Identities = 114/418 (27%), Positives = 146/418 (34%), Gaps = 106/418 (25%)

Query: 135  KGSPGPPPPVARATRKGP-GPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGSV-PCYPP 192
            KG PG     +  TR GP GP+G       PG+ GD      G+M   GP G + P  P 
Sbjct: 1053 KGEPG----YSEGTRPGPPGPTG------DPGLPGDMGK--KGEMGQPGPPGHLGPAGPE 1100

Query: 193  PAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAFPAV 252
             APG                 P SPGL    GP       + F      L PP    P  
Sbjct: 1101 GAPGS----------------PGSPGLPGKPGPH----GDLGFKGIKGLLGPPGIRGPPG 1140

Query: 253  QPPQRPTPAPRLYYPLLLEHTLGLPAGK---AALAKAPVSPR-SPSGTPAPGLLKVP-VP 307
             P    +P P           +  PAG+     L +AP  PR +P    A G    P  P
Sbjct: 1141 LPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGLLRAPPGPRGNPGAQGAKGDRGAPGFP 1200

Query: 308  GLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKAS-PSLTRFC----SRSSL 362
            GL          PG++G +  A    P           LP A  P  T       SR S 
Sbjct: 1201 GL----------PGRKGAMGDAGPRGPTGIEGFPGPPGLPGAIIPGQTGNRGPPGSRGSP 1250

Query: 363  -------PTGSSVMLWPEDGDPGGPETPGPEGPL----PLQPRGPV--PGSPEHVGEDLT 409
                   P GS V+     GD G    PGP+GP      + P G +  PG+P   G    
Sbjct: 1251 GAPGPPGPPGSHVI--GIKGDKGSMGHPGPKGPPGTAGDMGPPGRLGAPGTPGLPGPRGD 1308

Query: 410  RALGDYARVEQR------LGQLGPAGGLAPRP---LREQLGKIRLELLTIHQALEQAVRP 460
                 +  V+        LG +GP G + P+    +R   G +++       +L  +  P
Sbjct: 1309 PGFQGFPGVKGEKGNPGFLGSIGPPGPIGPKGPPGVRGDPGTLKII------SLPGSPGP 1362

Query: 461  PDAPLDLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTK 518
            P  P                GE   + E GP      P PPG LGP  P+   G   K
Sbjct: 1363 PGTP----------------GEPGMQGEPGP------PGPPGNLGPCGPRGKPGKDGK 1398



 Score = 49.7 bits (117), Expect = 7e-06
 Identities = 132/495 (26%), Positives = 158/495 (31%), Gaps = 137/495 (27%)

Query: 78  RGSTTPRPHAPTPDRPGESDPGRQP-------QGARPTGAAPAPDLVVADIHSLHCGGGP 130
           RG   P      P  PG S PG +        +G++     P  D  +    S  C G P
Sbjct: 368 RGPQGPSGPPGVPGSPGSSRPGLRGAPGWPGLKGSKGERGRPGKD-AMGTPGSPGCAGSP 426

Query: 131 KSRAKGSPGPP-PPVARATRKGP-GPSGLLPESWKPGMGGDPRGVGAGDMASAGPEGS-- 186
                GSPGPP PP     RKGP G  GL      PG  G P G+   D    GP+G   
Sbjct: 427 G--LPGSPGPPGPPGDIVFRKGPPGDHGL------PGYLGSP-GIPGVD----GPKGEPG 473

Query: 187 ---VPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLG-PSLAAAAHVPFLASASPL 242
                C   P P   P    LH  + G+  P   G     G P       +P      P 
Sbjct: 474 LLCTQCPYIPGPPGLPGLPGLH-GVKGI--PGRQGAAGLKGSPGSPGNTGLP----GFPG 526

Query: 243 LPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTP-APGL 301
            P A   P ++  +  T  P        E  +G+P G   L   P   +   G P  PG 
Sbjct: 527 FPGAQGDPGLKGEKGETLQP--------EGQVGVP-GDPGLRGQP-GRKGLDGIPGTPG- 575

Query: 302 LKVPVPGLGPWPRVTPRDPGQEGEL----ERAAQSDPRRRLSLGSRLELPKASPSLTRFC 357
               V GL          PG +GEL    E+  Q  P    S GS               
Sbjct: 576 ----VKGL----------PGPKGELALSGEKGDQGPPGDPGSPGS--------------- 606

Query: 358 SRSSLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRA-LGDYA 416
                         P    P GP   GP+G   LQ    VPG+P   GE   R  L    
Sbjct: 607 --------------PGPAGPAGPPGYGPQGEPGLQGTQGVPGAPGPPGEAGPRGELSVST 652

Query: 417 RVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPA-K 475
            V    G  GP G   P+                         PP  P  L     P   
Sbjct: 653 PVPGPPGPPGPPGHPGPQ------------------------GPPGIPGSLGKCGDPGLP 688

Query: 476 GPQALGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLPLAAP 535
           GP       G P +  +   G P PP   GP   Q F G          +  PGL    P
Sbjct: 689 GPD------GEPGIPGI---GFPGPP---GPKGDQGFPGTKGSLGCPGKMGEPGL----P 732

Query: 536 DDPVIPGSGWGTCVA 550
             P +PG+     VA
Sbjct: 733 GKPGLPGAKGEPAVA 747



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 99/393 (25%), Positives = 128/393 (32%), Gaps = 77/393 (19%)

Query: 81   TTPRPHAPTPDRPGESDPGRQPQGARPTGAAPAPDLVVADIHSLHCGGGPKSRAKGSPGP 140
            T P P  PT D     D G++ +  +P    P   L  A        G P S   G PG 
Sbjct: 1062 TRPGPPGPTGDPGLPGDMGKKGEMGQP---GPPGHLGPAGPEG--APGSPGS--PGLPGK 1114

Query: 141  PPPVARATRKGP----GPSGLLPESWKPGMGGDPRGVGA-------GDMASAGPEGSVPC 189
            P P      KG     GP G+      PG  G P  +G        G    AG +G    
Sbjct: 1115 PGPHGDLGFKGIKGLLGPPGIRGPPGLPGFPGSPGPMGIRGDQGRDGIPGPAGEKGETGL 1174

Query: 190  Y-PPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLG----------------PSLAAAAH 232
               PP P   P A           +P  PG    +G                P L  A  
Sbjct: 1175 LRAPPGPRGNPGAQGAKGDRGAPGFPGLPGRKGAMGDAGPRGPTGIEGFPGPPGLPGAII 1234

Query: 233  VPFLASASPLLPPATAFPAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRS 292
                 +  P  P +   P    P  P  +          H +G+   K ++      P+ 
Sbjct: 1235 PGQTGNRGP--PGSRGSPGAPGPPGPPGS----------HVIGIKGDKGSMGHP--GPKG 1280

Query: 293  PSGTPA----PGLLKVP-VPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLEL- 346
            P GT      PG L  P  PGL P PR  P   G  G   +  + +P    S+G    + 
Sbjct: 1281 PPGTAGDMGPPGRLGAPGTPGL-PGPRGDPGFQGFPGV--KGEKGNPGFLGSIGPPGPIG 1337

Query: 347  PKASPSLT------RFCSRSSLP----TGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGP 396
            PK  P +       +  S    P    T     +  E G PG P   GP GP     +  
Sbjct: 1338 PKGPPGVRGDPGTLKIISLPGSPGPPGTPGEPGMQGEPGPPGPPGNLGPCGPRGKPGKDG 1397

Query: 397  VPGSPEHVGEDLTRALGDYARVEQRLGQLGPAG 429
             PG+P   GE   +            G+ GPAG
Sbjct: 1398 KPGTPGPAGEKGNKG---------SKGEPGPAG 1421



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 107/412 (25%), Positives = 135/412 (32%), Gaps = 53/412 (12%)

Query: 134  AKGSPGPPPPVARATRKGPGPSGLLPESWKPGMGGDPRGVGA-GDMASAGPEGSVPCYPP 192
            AKG P    P    T   PG  G   E  + G+ G P   G  G+    GP G      P
Sbjct: 740  AKGEPAVAMPGGPGTPGFPGERGNSGEHGEIGLPGLPGLPGTPGNEGLDGPRGDPGQPGP 799

Query: 193  PA----PGEFPEAHSLHLSLLGVN-YPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPAT 247
            P     PG   E       L G+N      G     GP       +P L  +    P  T
Sbjct: 800  PGEQGPPGRCIEGPRGAQGLPGLNGLKGQQGRRGKTGPK--GDPGIPGLDRSG--FPGET 855

Query: 248  AFPAVQPPQRPT-PAPRLYYPLLLEHTLGLPAGKAALAK----APVSPRSPSGTPA-PGL 301
              P +   Q    P  +  YP      LG P     +        + P  P G P  PG 
Sbjct: 856  GSPGIPGHQGEMGPLGQRGYPGN-PGILGPPGEDGVIGMMGFPGAIGPPGPPGNPGTPGQ 914

Query: 302  LKVP-VPGLGPWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCSRS 360
               P +PG+    R TP   G++G+      S+    +         K  P L  F    
Sbjct: 915  RGSPGIPGV-KGQRGTPGAKGEQGDKGNPGPSEISHVIG-------DKGEPGLKGFAGNP 966

Query: 361  SLPTGSSVMLWPEDGDPGGPETPGPEGPLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQ 420
                   V   P  G  G    PGP GP    PRG + GS  + GE   R       +  
Sbjct: 967  GEKGNRGVPGMP--GLKGLKGLPGPAGPPG--PRGDL-GSTGNPGEPGLRG------IPG 1015

Query: 421  RLGQLGPAGGLAPRPLREQLGKI-RLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQA 479
             +G +G  G    R      G+  R  L  IH        P  +         P   P  
Sbjct: 1016 SMGNMGMPGSKGKRGTLGFPGRAGRPGLPGIHGLQGDKGEPGYSEGTRPGPPGPTGDPGL 1075

Query: 480  LGEAWGRPELGPVLTGGTPEPPGMLGPAAPQPFSGHTTKCEADSSVPPPGLP 531
             G+   + E+G       P PPG LGPA P+          A  S   PGLP
Sbjct: 1076 PGDMGKKGEMGQ------PGPPGHLGPAGPE---------GAPGSPGSPGLP 1112



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 117/469 (24%), Positives = 147/469 (31%), Gaps = 114/469 (24%)

Query: 134 AKGSPGPPPPVARATRKGPGPSGLLPESWKPGMGGDPRGVG----AGDMASAGPEGSVPC 189
           AKG PG P          PGP GL      PG  G P   G     G M   GP+G +  
Sbjct: 169 AKGDPGLPG--------APGPQGLPGPPGFPGPVGPPGPPGFFGFPGAMGPRGPKGHM-- 218

Query: 190 YPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSYLGPSLAAAAHVPFLASASPLLPPATAF 249
                 GE    H     + G+  P  PG                         PP T  
Sbjct: 219 ------GERVIGHKGERGVKGLTGP--PG-------------------------PPGTVI 245

Query: 250 PAVQPPQRPTPAPRLYYPLLLEHTLGLPAGKAALAKAPVSPRSPSGTP---------APG 300
             +  P   T               G    K A+ +    P  PSG P         APG
Sbjct: 246 VTLTGPDNRTDLK------------GEKGDKGAMGEP--GPPGPSGLPGESYGSEKGAPG 291

Query: 301 LLKVPVPGLG--PWPRVTPRDPGQEGELERAAQSDPRRRLSLGSRLELPKASPSLTRFCS 358
                 PGL   P     P  PG EG   +  +  P      G + +     P   R   
Sbjct: 292 -----DPGLQGKPGKDGVPGFPGSEGV--KGNRGFPGLMGEDGIKGQKGDIGPPGFRG-- 342

Query: 359 RSSLPTGSSVMLWPEDGDPGGPETPGPEGPL-PLQPRGP--VPGSPEHVGEDLTRALGDY 415
               PT      + E GD G P  PGP G   P  P GP  VPGSP      L  A G +
Sbjct: 343 ----PT-EYYDTYQEKGDEGTPGPPGPRGARGPQGPSGPPGVPGSPGSSRPGLRGAPG-W 396

Query: 416 ARVEQRLGQLGPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAK 475
             ++   G+ G       RP ++ +G            L  +  PP  P D+  ++ P  
Sbjct: 397 PGLKGSKGERG-------RPGKDAMGTPGSPGCAGSPGLPGSPGPPGPPGDIVFRKGP-P 448

Query: 476 GPQALGEAWGRPEL----GPVLTGG--------TPEPPGMLGPAAPQPFSGHTTKCEADS 523
           G   L    G P +    GP    G         P PPG+ G        G   +  A  
Sbjct: 449 GDHGLPGYLGSPGIPGVDGPKGEPGLLCTQCPYIPGPPGLPGLPGLHGVKGIPGRQGAAG 508

Query: 524 SVPPPGLP--LAAPDDPVIPGSGWGTCVATRSSQT--PEAVCGLQSPQG 568
               PG P     P  P  PG+     +     +T  PE   G+    G
Sbjct: 509 LKGSPGSPGNTGLPGFPGFPGAQGDPGLKGEKGETLQPEGQVGVPGDPG 557



 Score = 37.0 bits (84), Expect = 0.049
 Identities = 48/156 (30%), Positives = 56/156 (35%), Gaps = 15/156 (9%)

Query: 373 EDGDPGGPETP------GPEG-PLPLQPRGPVPGSPEHVGEDLTRALGDYARVEQRLGQL 425
           E G PG P +P      GPEG P P  P+G  PG P   G    R +          G  
Sbjct: 50  EKGFPGPPGSPGQKGFTGPEGLPGPQGPKG-FPGLPGLTGSKGVRGISGLPGFSGSPGLP 108

Query: 426 GPAGGLAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSV---KRAPAKGPQALGE 482
           G  G   P  L    G    +       L   +  P  P    +   K APAK      +
Sbjct: 109 GTPGNTGPYGLVGVPGCSGSKGEQGFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELD 168

Query: 483 AWGRPEL----GPVLTGGTPEPPGMLGPAAPQPFSG 514
           A G P L    GP    G P  PG +GP  P  F G
Sbjct: 169 AKGDPGLPGAPGPQGLPGPPGFPGPVGPPGPPGFFG 204



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 114/443 (25%), Positives = 144/443 (32%), Gaps = 106/443 (23%)

Query: 110 AAPAPD--LVVADIHSLHCGGGPKSRA-KGSPGPPPPVARATRKGP----GPSGLLPESW 162
           AAPA     V  D     C G    +  KG PGPP    +    GP    GP G      
Sbjct: 23  AAPAASKGCVCKDKGQCFCDGAKGEKGEKGFPGPPGSPGQKGFTGPEGLPGPQGPKGFPG 82

Query: 163 KPGMGGDPRGVGAGDMASAGPEGSVPCYPPPAPGEFPEAHSLHLSLLGVNYPLSPGLFSY 222
            PG+ G  +GV  G     G  GS     P  PG     ++    L+GV     PG    
Sbjct: 83  LPGLTGS-KGV-RGISGLPGFSGS-----PGLPGT--PGNTGPYGLVGV-----PGCSGS 128

Query: 223 LGPSLAAAAHVPFLASASPLLPPATAFPAVQPP-----QRPTPAPRLYYPLLLEHTLGLP 277
            G                P LP    +P +        Q+  PA      L  +   GLP
Sbjct: 129 KGEQ------------GFPGLPGTLGYPGIPGAAGLKGQKGAPAKEEDIELDAKGDPGLP 176

Query: 278 A--GKAALAKAPVSPRSPSGTPAPGLLKVPVPGLGPWP-RVTPRDP-GQEGELERAAQSD 333
              G   L   P  P  P G P P       PG   +P  + PR P G  GE     + +
Sbjct: 177 GAPGPQGLPGPPGFP-GPVGPPGP-------PGFFGFPGAMGPRGPKGHMGERVIGHKGE 228

Query: 334 PRRRLSLGSRLELPKASPSLTRFCSRSSLPTGSSVMLWPEDGDPGGPETPGPEGP--LPL 391
              +   G          +LT   +R+ L          E GD G    PGP GP  LP 
Sbjct: 229 RGVKGLTGPPGPPGTVIVTLTGPDNRTDLKG--------EKGDKGAMGEPGPPGPSGLPG 280

Query: 392 QPRGP---VPGSPEHVGEDLTRALGDYARVEQRLGQLGPAGGLAPRPLREQLGKIRLELL 448
           +  G     PG P   G+     +  +   E   G  G  G +    ++ Q G I     
Sbjct: 281 ESYGSEKGAPGDPGLQGKPGKDGVPGFPGSEGVKGNRGFPGLMGEDGIKGQKGDI----- 335

Query: 449 TIHQALEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRPELGPVLTGGTPEPPGMLGPAA 508
                      PP             +GP    + +   E G     GTP PPG  G   
Sbjct: 336 ----------GPPG-----------FRGPTEYYDTY--QEKG---DEGTPGPPGPRGARG 369

Query: 509 PQPFSGHTTKCEADSSVPPPGLP 531
           PQ  SG            PPG+P
Sbjct: 370 PQGPSG------------PPGVP 380



 Score = 34.7 bits (78), Expect = 0.24
 Identities = 57/184 (30%), Positives = 66/184 (35%), Gaps = 54/184 (29%)

Query: 375 GDPGGPETPGPEGPLPLQPRGPVPGSPEHVGED----LTRALGDYARVEQRLGQLGPAGG 430
           G PG P TPG  GP  L     VPG     GE     L   LG Y  +    G  G  G 
Sbjct: 103 GSPGLPGTPGNTGPYGLV---GVPGCSGSKGEQGFPGLPGTLG-YPGIPGAAGLKGQKGA 158

Query: 431 LAPRPLREQLGKIRLELLTIHQALEQAVRPPDAPLDLSVKRAPAKGPQALGEAWGRPELG 490
               P +E+     +EL              DA  D  +  AP  GPQ L    G P  G
Sbjct: 159 ----PAKEE----DIEL--------------DAKGDPGLPGAP--GPQGLPGPPGFP--G 192

Query: 491 PVLTGGTPEPPGM------LGPAAP-----QPFSGHTTKCEADSSVPPPGLP------LA 533
           PV   G P PPG       +GP  P     +   GH  +        PPG P      L 
Sbjct: 193 PV---GPPGPPGFFGFPGAMGPRGPKGHMGERVIGHKGERGVKGLTGPPGPPGTVIVTLT 249

Query: 534 APDD 537
            PD+
Sbjct: 250 GPDN 253


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.137    0.441 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,180,051
Number of Sequences: 37866
Number of extensions: 2829487
Number of successful extensions: 25201
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 159
Number of HSP's successfully gapped in prelim test: 1525
Number of HSP's that attempted gapping in prelim test: 13759
Number of HSP's gapped (non-prelim): 7879
length of query: 571
length of database: 18,247,518
effective HSP length: 108
effective length of query: 463
effective length of database: 14,157,990
effective search space: 6555149370
effective search space used: 6555149370
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.