Guide to the Human Genome
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Search of human proteins with 113426528

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|113426528 PREDICTED: similar to hCG2042536 [Homo sapiens]
         (847 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|113426528 PREDICTED: similar to hCG2042536 [Homo sapiens]         1769   0.0  
gi|113426210 PREDICTED: similar to hCG2042536 [Homo sapiens]         1768   0.0  
gi|239756641 PREDICTED: similar to hCG2042536 [Homo sapiens]         1162   0.0  
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    53   1e-06
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    53   1e-06
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    53   1e-06
gi|12707580 paired-like homeobox 2b [Homo sapiens]                     49   3e-05
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    48   3e-05
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    48   3e-05
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      48   3e-05
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]    47   1e-04
gi|119829187 alpha 1 type XVII collagen [Homo sapiens]                 46   2e-04
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      45   3e-04
gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [H...    45   3e-04
gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Ho...    45   3e-04
gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Hom...    45   3e-04
gi|156071470 hyperpolarization activated cyclic nucleotide-gated...    45   4e-04
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       44   5e-04
gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3...    44   5e-04
gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1...    44   5e-04
gi|156151392 heterogeneous nuclear ribonucleoprotein R isoform 4...    44   5e-04
gi|5031755 heterogeneous nuclear ribonucleoprotein R isoform 2 [...    44   5e-04
gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens]     44   6e-04
gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens]     44   6e-04
gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]                44   6e-04
gi|67188550 CTD (carboxy-terminal domain, RNA polymerase II, pol...    44   8e-04
gi|67188445 CTD (carboxy-terminal domain, RNA polymerase II, pol...    44   8e-04
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]      44   8e-04
gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens]        44   8e-04
gi|4758876 poly(A) binding protein, nuclear 1 [Homo sapiens]           43   0.001

>gi|113426528 PREDICTED: similar to hCG2042536 [Homo sapiens]
          Length = 847

 Score = 1769 bits (4582), Expect = 0.0
 Identities = 847/847 (100%), Positives = 847/847 (100%)

Query: 1   MSGRPAPVSRKQRLMAAVGERAAGGAPLSCFICGGGIGRGKELKLQVKQPAAGAGTPAQP 60
           MSGRPAPVSRKQRLMAAVGERAAGGAPLSCFICGGGIGRGKELKLQVKQPAAGAGTPAQP
Sbjct: 1   MSGRPAPVSRKQRLMAAVGERAAGGAPLSCFICGGGIGRGKELKLQVKQPAAGAGTPAQP 60

Query: 61  FFPFLQQQEPAPGARELSPADGCVLVCAVCRCFLGEQWAAFERARTPVDKRMYWLKRPHQ 120
           FFPFLQQQEPAPGARELSPADGCVLVCAVCRCFLGEQWAAFERARTPVDKRMYWLKRPHQ
Sbjct: 61  FFPFLQQQEPAPGARELSPADGCVLVCAVCRCFLGEQWAAFERARTPVDKRMYWLKRPHQ 120

Query: 121 CDAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTD 180
           CDAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTD
Sbjct: 121 CDAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTD 180

Query: 181 PLSEPDPPARDAASPHQDGAPGPGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPA 240
           PLSEPDPPARDAASPHQDGAPGPGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPA
Sbjct: 181 PLSEPDPPARDAASPHQDGAPGPGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPA 240

Query: 241 KAHADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEAPADGMKGPPSGRA 300
           KAHADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEAPADGMKGPPSGRA
Sbjct: 241 KAHADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEAPADGMKGPPSGRA 300

Query: 301 TKTLESRPLGETLRGFCTSEDSDINITSGEEDHKEQPFPGVCNPKEKNSGRVPRALQDSR 360
           TKTLESRPLGETLRGFCTSEDSDINITSGEEDHKEQPFPGVCNPKEKNSGRVPRALQDSR
Sbjct: 301 TKTLESRPLGETLRGFCTSEDSDINITSGEEDHKEQPFPGVCNPKEKNSGRVPRALQDSR 360

Query: 361 AAPAEGLCCYICGAPLSPASHHQVHVQKQEKLAQAPFFPFLWLHSPPPGAQPISEGGSTL 420
           AAPAEGLCCYICGAPLSPASHHQVHVQKQEKLAQAPFFPFLWLHSPPPGAQPISEGGSTL
Sbjct: 361 AAPAEGLCCYICGAPLSPASHHQVHVQKQEKLAQAPFFPFLWLHSPPPGAQPISEGGSTL 420

Query: 421 VCASCFSSLTQQWQSFELANVPVLQRLYVVPLDSHAPGMASKGRRLPREEGLPSGALREA 480
           VCASCFSSLTQQWQSFELANVPVLQRLYVVPLDSHAPGMASKGRRLPREEGLPSGALREA
Sbjct: 421 VCASCFSSLTQQWQSFELANVPVLQRLYVVPLDSHAPGMASKGRRLPREEGLPSGALREA 480

Query: 481 CYLCGEDCTPDARAVPSRILNGNARSAMHFPFLSLLPCPPNAQGPNKRCEVRSCPKCFSV 540
           CYLCGEDCTPDARAVPSRILNGNARSAMHFPFLSLLPCPPNAQGPNKRCEVRSCPKCFSV
Sbjct: 481 CYLCGEDCTPDARAVPSRILNGNARSAMHFPFLSLLPCPPNAQGPNKRCEVRSCPKCFSV 540

Query: 541 LEDVWALYRACQNEELITSVQGFLGRYHQAFSASDPALSELPASAQGGPVSICYICGAEL 600
           LEDVWALYRACQNEELITSVQGFLGRYHQAFSASDPALSELPASAQGGPVSICYICGAEL
Sbjct: 541 LEDVWALYRACQNEELITSVQGFLGRYHQAFSASDPALSELPASAQGGPVSICYICGAEL 600

Query: 601 GPGKEFQLNVNPASRLGEKEPFFPFLTVYPPAPRARPVDSTGLVATCVLCYHDLLAQWLQ 660
           GPGKEFQLNVNPASRLGEKEPFFPFLTVYPPAPRARPVDSTGLVATCVLCYHDLLAQWLQ
Sbjct: 601 GPGKEFQLNVNPASRLGEKEPFFPFLTVYPPAPRARPVDSTGLVATCVLCYHDLLAQWLQ 660

Query: 661 HEARSSHHAVSAWSRQYQVETFVCFFCQQEKKRCLGLKSVRVARLPLFLYTLRASHSLLV 720
           HEARSSHHAVSAWSRQYQVETFVCFFCQQEKKRCLGLKSVRVARLPLFLYTLRASHSLLV
Sbjct: 661 HEARSSHHAVSAWSRQYQVETFVCFFCQQEKKRCLGLKSVRVARLPLFLYTLRASHSLLV 720

Query: 721 DDGQQLIIGACVECGTLVCAGQGLTRQGPMSWSSPVAAATKMNRRCFHYDAAPPSLAASL 780
           DDGQQLIIGACVECGTLVCAGQGLTRQGPMSWSSPVAAATKMNRRCFHYDAAPPSLAASL
Sbjct: 721 DDGQQLIIGACVECGTLVCAGQGLTRQGPMSWSSPVAAATKMNRRCFHYDAAPPSLAASL 780

Query: 781 SWHLFYLNYSHLDTEVSEVRRGKVTCPRPHRCQLQGQSAPFSAQLHTGFLYSNSRFGAMG 840
           SWHLFYLNYSHLDTEVSEVRRGKVTCPRPHRCQLQGQSAPFSAQLHTGFLYSNSRFGAMG
Sbjct: 781 SWHLFYLNYSHLDTEVSEVRRGKVTCPRPHRCQLQGQSAPFSAQLHTGFLYSNSRFGAMG 840

Query: 841 LRDAPSQ 847
           LRDAPSQ
Sbjct: 841 LRDAPSQ 847


>gi|113426210 PREDICTED: similar to hCG2042536 [Homo sapiens]
          Length = 847

 Score = 1768 bits (4579), Expect = 0.0
 Identities = 846/847 (99%), Positives = 847/847 (100%)

Query: 1   MSGRPAPVSRKQRLMAAVGERAAGGAPLSCFICGGGIGRGKELKLQVKQPAAGAGTPAQP 60
           MSGRPAPVSRKQRLMAAVGERAAGGAPLSCFICGGGIGRGKELKLQVKQPAAGAGTPAQP
Sbjct: 1   MSGRPAPVSRKQRLMAAVGERAAGGAPLSCFICGGGIGRGKELKLQVKQPAAGAGTPAQP 60

Query: 61  FFPFLQQQEPAPGARELSPADGCVLVCAVCRCFLGEQWAAFERARTPVDKRMYWLKRPHQ 120
           FFPFLQQQEPAPGARELSPADGCVLVCAVCRCFLGEQWAAFERARTPVDKRMYWLKRPHQ
Sbjct: 61  FFPFLQQQEPAPGARELSPADGCVLVCAVCRCFLGEQWAAFERARTPVDKRMYWLKRPHQ 120

Query: 121 CDAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTD 180
           CDAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTD
Sbjct: 121 CDAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTD 180

Query: 181 PLSEPDPPARDAASPHQDGAPGPGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPA 240
           PLSEPDPPARDAASPHQDGAPGPGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPA
Sbjct: 181 PLSEPDPPARDAASPHQDGAPGPGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPA 240

Query: 241 KAHADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEAPADGMKGPPSGRA 300
           KAHADGEPK+GVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEAPADGMKGPPSGRA
Sbjct: 241 KAHADGEPKSGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEAPADGMKGPPSGRA 300

Query: 301 TKTLESRPLGETLRGFCTSEDSDINITSGEEDHKEQPFPGVCNPKEKNSGRVPRALQDSR 360
           TKTLESRPLGETLRGFCTSEDSDINITSGEEDHKEQPFPGVCNPKEKNSGRVPRALQDSR
Sbjct: 301 TKTLESRPLGETLRGFCTSEDSDINITSGEEDHKEQPFPGVCNPKEKNSGRVPRALQDSR 360

Query: 361 AAPAEGLCCYICGAPLSPASHHQVHVQKQEKLAQAPFFPFLWLHSPPPGAQPISEGGSTL 420
           AAPAEGLCCYICGAPLSPASHHQVHVQKQEKLAQAPFFPFLWLHSPPPGAQPISEGGSTL
Sbjct: 361 AAPAEGLCCYICGAPLSPASHHQVHVQKQEKLAQAPFFPFLWLHSPPPGAQPISEGGSTL 420

Query: 421 VCASCFSSLTQQWQSFELANVPVLQRLYVVPLDSHAPGMASKGRRLPREEGLPSGALREA 480
           VCASCFSSLTQQWQSFELANVPVLQRLYVVPLDSHAPGMASKGRRLPREEGLPSGALREA
Sbjct: 421 VCASCFSSLTQQWQSFELANVPVLQRLYVVPLDSHAPGMASKGRRLPREEGLPSGALREA 480

Query: 481 CYLCGEDCTPDARAVPSRILNGNARSAMHFPFLSLLPCPPNAQGPNKRCEVRSCPKCFSV 540
           CYLCGEDCTPDARAVPSRILNGNARSAMHFPFLSLLPCPPNAQGPNKRCEVRSCPKCFSV
Sbjct: 481 CYLCGEDCTPDARAVPSRILNGNARSAMHFPFLSLLPCPPNAQGPNKRCEVRSCPKCFSV 540

Query: 541 LEDVWALYRACQNEELITSVQGFLGRYHQAFSASDPALSELPASAQGGPVSICYICGAEL 600
           LEDVWALYRACQNEELITSVQGFLGRYHQAFSASDPALSELPASAQGGPVSICYICGAEL
Sbjct: 541 LEDVWALYRACQNEELITSVQGFLGRYHQAFSASDPALSELPASAQGGPVSICYICGAEL 600

Query: 601 GPGKEFQLNVNPASRLGEKEPFFPFLTVYPPAPRARPVDSTGLVATCVLCYHDLLAQWLQ 660
           GPGKEFQLNVNPASRLGEKEPFFPFLTVYPPAPRARPVDSTGLVATCVLCYHDLLAQWLQ
Sbjct: 601 GPGKEFQLNVNPASRLGEKEPFFPFLTVYPPAPRARPVDSTGLVATCVLCYHDLLAQWLQ 660

Query: 661 HEARSSHHAVSAWSRQYQVETFVCFFCQQEKKRCLGLKSVRVARLPLFLYTLRASHSLLV 720
           HEARSSHHAVSAWSRQYQVETFVCFFCQQEKKRCLGLKSVRVARLPLFLYTLRASHSLLV
Sbjct: 661 HEARSSHHAVSAWSRQYQVETFVCFFCQQEKKRCLGLKSVRVARLPLFLYTLRASHSLLV 720

Query: 721 DDGQQLIIGACVECGTLVCAGQGLTRQGPMSWSSPVAAATKMNRRCFHYDAAPPSLAASL 780
           DDGQQLIIGACVECGTLVCAGQGLTRQGPMSWSSPVAAATKMNRRCFHYDAAPPSLAASL
Sbjct: 721 DDGQQLIIGACVECGTLVCAGQGLTRQGPMSWSSPVAAATKMNRRCFHYDAAPPSLAASL 780

Query: 781 SWHLFYLNYSHLDTEVSEVRRGKVTCPRPHRCQLQGQSAPFSAQLHTGFLYSNSRFGAMG 840
           SWHLFYLNYSHLDTEVSEVRRGKVTCPRPHRCQLQGQSAPFSAQLHTGFLYSNSRFGAMG
Sbjct: 781 SWHLFYLNYSHLDTEVSEVRRGKVTCPRPHRCQLQGQSAPFSAQLHTGFLYSNSRFGAMG 840

Query: 841 LRDAPSQ 847
           LRDAPSQ
Sbjct: 841 LRDAPSQ 847


>gi|239756641 PREDICTED: similar to hCG2042536 [Homo sapiens]
          Length = 556

 Score = 1162 bits (3005), Expect = 0.0
 Identities = 556/556 (100%), Positives = 556/556 (100%)

Query: 292 MKGPPSGRATKTLESRPLGETLRGFCTSEDSDINITSGEEDHKEQPFPGVCNPKEKNSGR 351
           MKGPPSGRATKTLESRPLGETLRGFCTSEDSDINITSGEEDHKEQPFPGVCNPKEKNSGR
Sbjct: 1   MKGPPSGRATKTLESRPLGETLRGFCTSEDSDINITSGEEDHKEQPFPGVCNPKEKNSGR 60

Query: 352 VPRALQDSRAAPAEGLCCYICGAPLSPASHHQVHVQKQEKLAQAPFFPFLWLHSPPPGAQ 411
           VPRALQDSRAAPAEGLCCYICGAPLSPASHHQVHVQKQEKLAQAPFFPFLWLHSPPPGAQ
Sbjct: 61  VPRALQDSRAAPAEGLCCYICGAPLSPASHHQVHVQKQEKLAQAPFFPFLWLHSPPPGAQ 120

Query: 412 PISEGGSTLVCASCFSSLTQQWQSFELANVPVLQRLYVVPLDSHAPGMASKGRRLPREEG 471
           PISEGGSTLVCASCFSSLTQQWQSFELANVPVLQRLYVVPLDSHAPGMASKGRRLPREEG
Sbjct: 121 PISEGGSTLVCASCFSSLTQQWQSFELANVPVLQRLYVVPLDSHAPGMASKGRRLPREEG 180

Query: 472 LPSGALREACYLCGEDCTPDARAVPSRILNGNARSAMHFPFLSLLPCPPNAQGPNKRCEV 531
           LPSGALREACYLCGEDCTPDARAVPSRILNGNARSAMHFPFLSLLPCPPNAQGPNKRCEV
Sbjct: 181 LPSGALREACYLCGEDCTPDARAVPSRILNGNARSAMHFPFLSLLPCPPNAQGPNKRCEV 240

Query: 532 RSCPKCFSVLEDVWALYRACQNEELITSVQGFLGRYHQAFSASDPALSELPASAQGGPVS 591
           RSCPKCFSVLEDVWALYRACQNEELITSVQGFLGRYHQAFSASDPALSELPASAQGGPVS
Sbjct: 241 RSCPKCFSVLEDVWALYRACQNEELITSVQGFLGRYHQAFSASDPALSELPASAQGGPVS 300

Query: 592 ICYICGAELGPGKEFQLNVNPASRLGEKEPFFPFLTVYPPAPRARPVDSTGLVATCVLCY 651
           ICYICGAELGPGKEFQLNVNPASRLGEKEPFFPFLTVYPPAPRARPVDSTGLVATCVLCY
Sbjct: 301 ICYICGAELGPGKEFQLNVNPASRLGEKEPFFPFLTVYPPAPRARPVDSTGLVATCVLCY 360

Query: 652 HDLLAQWLQHEARSSHHAVSAWSRQYQVETFVCFFCQQEKKRCLGLKSVRVARLPLFLYT 711
           HDLLAQWLQHEARSSHHAVSAWSRQYQVETFVCFFCQQEKKRCLGLKSVRVARLPLFLYT
Sbjct: 361 HDLLAQWLQHEARSSHHAVSAWSRQYQVETFVCFFCQQEKKRCLGLKSVRVARLPLFLYT 420

Query: 712 LRASHSLLVDDGQQLIIGACVECGTLVCAGQGLTRQGPMSWSSPVAAATKMNRRCFHYDA 771
           LRASHSLLVDDGQQLIIGACVECGTLVCAGQGLTRQGPMSWSSPVAAATKMNRRCFHYDA
Sbjct: 421 LRASHSLLVDDGQQLIIGACVECGTLVCAGQGLTRQGPMSWSSPVAAATKMNRRCFHYDA 480

Query: 772 APPSLAASLSWHLFYLNYSHLDTEVSEVRRGKVTCPRPHRCQLQGQSAPFSAQLHTGFLY 831
           APPSLAASLSWHLFYLNYSHLDTEVSEVRRGKVTCPRPHRCQLQGQSAPFSAQLHTGFLY
Sbjct: 481 APPSLAASLSWHLFYLNYSHLDTEVSEVRRGKVTCPRPHRCQLQGQSAPFSAQLHTGFLY 540

Query: 832 SNSRFGAMGLRDAPSQ 847
           SNSRFGAMGLRDAPSQ
Sbjct: 541 SNSRFGAMGLRDAPSQ 556



 Score = 64.7 bits (156), Expect = 3e-10
 Identities = 37/93 (39%), Positives = 49/93 (52%), Gaps = 4/93 (4%)

Query: 21  RAAGGAPLSCFICGGGIGRGKELKLQVKQPAAGAGTPAQPFFPFLQQQEPAPGARELSPA 80
           RAA    L C+ICG  +      ++ V++    A  P   FFPFL    P PGA+ +S  
Sbjct: 69  RAAPAEGLCCYICGAPLSPASHHQVHVQKQEKLAQAP---FFPFLWLHSPPPGAQPISEG 125

Query: 81  DGCVLVCAVCRCFLGEQWAAFERARTPVDKRMY 113
            G  LVCA C   L +QW +FE A  PV +R+Y
Sbjct: 126 -GSTLVCASCFSSLTQQWQSFELANVPVLQRLY 157



 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 36/82 (43%), Positives = 46/82 (56%), Gaps = 4/82 (4%)

Query: 22  AAGGAPLS-CFICGGGIGRGKELKLQVKQPAAGAGTPAQPFFPFLQQQEPAPGARELSPA 80
           +A G P+S C+ICG  +G GKE +L V  PA+  G   +PFFPFL    PAP AR +  +
Sbjct: 293 SAQGGPVSICYICGAELGPGKEFQLNV-NPASRLG-EKEPFFPFLTVYPPAPRARPVD-S 349

Query: 81  DGCVLVCAVCRCFLGEQWAAFE 102
            G V  C +C   L  QW   E
Sbjct: 350 TGLVATCVLCYHDLLAQWLQHE 371


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 57/205 (27%), Positives = 72/205 (35%), Gaps = 44/205 (21%)

Query: 122  DAGAGGRRGGAGAPREWNVAYALG-----SATGDDDEDDGGGPRLRGAAEETRDSDLSEL 176
            +AG GG +G  G   E     A G        GDD      GP             +   
Sbjct: 1280 EAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGP-------------VGFP 1326

Query: 177  SDTDPLSEPDPPARDAASPH--QDGAPG-PGPRGGRGQEWRPAPGPAPGQGAEASAQGRA 233
             D  P  EP P  +D       +DG PG PGP G  G+   P P    G    A A+GR 
Sbjct: 1327 GDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQ 1386

Query: 234  EEEGLPAKAHADGEP----------------KAGVRRRRKGVGRHWVPEARASVLRSIQD 277
             E+G   +A A+G P                  G+R     VG   +P A        QD
Sbjct: 1387 GEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAG------QD 1440

Query: 278  PWQGPLVQEAPADGMKGPPSGRATK 302
               GP+       G+KG P  +  K
Sbjct: 1441 GPPGPMGPPG-LPGLKGDPGSKGEK 1464



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 56/189 (29%), Positives = 70/189 (37%), Gaps = 24/189 (12%)

Query: 119  HQCDAGAGGRRGGAGAPREWNVAYALGSA--TGDDDEDDGGGPRLRGAAEETRDSDLSEL 176
            H    G  G +G  G P    V    G    TG   E    GP      +    +   E 
Sbjct: 959  HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEG 1018

Query: 177  SDTDP----LSEPDPPARDAASPHQDGAPG----PGPRGGRGQEWRPAPGPAPGQGAEAS 228
            +  DP    +S  D PA     P + G PG    PG +GG G +  P P  +PG   E  
Sbjct: 1019 AKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG---ERG 1075

Query: 229  AQGRAEEEGLPAKAHADGEP-KAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEA 287
            + G A   GLP +    G P  AG     KG      P+  A      +D  QGP+    
Sbjct: 1076 SAGTAGPIGLPGRPGPQGPPGPAG----EKGAPGEKGPQGPAG-----RDGVQGPVGLPG 1126

Query: 288  PADGMKGPP 296
            PA G  G P
Sbjct: 1127 PA-GPAGSP 1134



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 55/187 (29%), Positives = 67/187 (35%), Gaps = 20/187 (10%)

Query: 120  QCDAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPR----LRGAAEETRDSDLSE 175
            Q   GA G  GG G P         G   GD+      GP     L+G      +    E
Sbjct: 1167 QGPVGAPGIAGGDGEPGPRGQQGMFGQK-GDEGARGFPGPPGPIGLQGLPGPPGEK--GE 1223

Query: 176  LSDTDPLSEPDPPA-RDAASPH-QDGAPGP----GPRGGRGQEWRPAPGPAPGQGAEASA 229
              D  P+  P PP  R    P+  DG  GP    G  GG G++  P     PG   EA  
Sbjct: 1224 NGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGV 1283

Query: 230  QGRAEEEGLPAKAHADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEAPA 289
             G   E G   +A   G P A      KG      P+     +    DP  GP  +  PA
Sbjct: 1284 GGPKGERGEKGEA---GPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDP--GPPGEPGPA 1338

Query: 290  --DGMKG 294
              DG+ G
Sbjct: 1339 GQDGVGG 1345



 Score = 35.8 bits (81), Expect = 0.17
 Identities = 59/209 (28%), Positives = 72/209 (34%), Gaps = 55/209 (26%)

Query: 122 DAGAGGRRGGAGAPREWNVAYALGSATGDDD---EDDGGGPRLRGAAEETRDSDLSELSD 178
           D G  G RG  G P             GDD    ED   GPR  G   E     L     
Sbjct: 623 DKGHRGERGPQGPP----------GPPGDDGMRGEDGEIGPR--GLPGEAGPRGL----- 665

Query: 179 TDPLSEPDPPARDAASPHQDGAPGP-------GPRGGRGQEWRPAPGPAPG-QG-----A 225
             P   P  P +   +   DG PGP       G  G  GQ+  P P   PG QG      
Sbjct: 666 LGPRGTPGAPGQPGMAG-VDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPG 724

Query: 226 EASAQGRAEEEGLPAKAHADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDPW-QGPLV 284
           E   QG+    GLP    ADG P             H   E ++    ++  P  QGP+ 
Sbjct: 725 EKGPQGKPGLAGLPG---ADGPP------------GHPGKEGQSGEKGALGPPGPQGPIG 769

Query: 285 QEAP-----ADGMKGPPSGRATKTLESRP 308
              P     ADG++G    +  K  +  P
Sbjct: 770 YPGPRGVKGADGVRGLKGSKGEKGEDGFP 798



 Score = 35.8 bits (81), Expect = 0.17
 Identities = 31/129 (24%), Positives = 46/129 (35%), Gaps = 16/129 (12%)

Query: 122  DAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDP 181
            D G+ G +G  G      +   +G      ++ D G P  +G+     D  +       P
Sbjct: 1457 DPGSKGEKGHPG------LIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIP--GPAGP 1508

Query: 182  LSEPDPPARDAASPHQDGAPGPGPRGGRGQEWRPAPGPAPGQGAE--------ASAQGRA 233
            L  P PP        +      GP G +G    P P  +PG   E        +S + R 
Sbjct: 1509 LGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRR 1568

Query: 234  EEEGLPAKA 242
              EG+ A A
Sbjct: 1569 HTEGMQADA 1577



 Score = 35.0 bits (79), Expect = 0.29
 Identities = 33/127 (25%), Positives = 44/127 (34%), Gaps = 10/127 (7%)

Query: 124  GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLS 183
            G+ G RG AG      +    G         + G P  +G         +       P+ 
Sbjct: 1069 GSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQ-----GPVG 1123

Query: 184  EPDPPARDAASPHQDGAPG----PGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLP 239
             P P A  A SP +DG  G    PG +G +G +    P   PG      A G A  +G P
Sbjct: 1124 LPGP-AGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEP 1182

Query: 240  AKAHADG 246
                  G
Sbjct: 1183 GPRGQQG 1189



 Score = 35.0 bits (79), Expect = 0.29
 Identities = 51/190 (26%), Positives = 63/190 (33%), Gaps = 15/190 (7%)

Query: 124  GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGA-AEETRDSDLSELSDTDPL 182
            G GG +G  G P +       G A         G P   GA   +       E     P 
Sbjct: 1342 GVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPP 1401

Query: 183  SEPDP--PARDAASPHQDGAPG-PGP------RGGRGQEWRPAPGPAPGQGAEASAQGRA 233
             +  P  P   A  P  +G  G PGP       G  GQ+  P P   PG        G  
Sbjct: 1402 GKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSK 1461

Query: 234  EEEGLPAKAHADGEP-KAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEAPADGM 292
             E+G P      G P + G +  R   G    P A+      I  P  GPL    P  G+
Sbjct: 1462 GEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGD--GGIPGP-AGPLGPPGP-PGL 1517

Query: 293  KGPPSGRATK 302
             GP   +  K
Sbjct: 1518 PGPQGPKGNK 1527



 Score = 33.5 bits (75), Expect = 0.85
 Identities = 20/57 (35%), Positives = 26/57 (45%), Gaps = 7/57 (12%)

Query: 195 PHQDGAPG----PGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPAKAHADGE 247
           P   GA G    PGP+G RG +  P P   PG+     A G     G+P +  A G+
Sbjct: 558 PGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADG---GRGMPGEPGAKGD 611



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 18/50 (36%), Positives = 21/50 (42%), Gaps = 1/50 (2%)

Query: 198 DGAPG-PGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPAKAHADG 246
           DG PG PG +G RG+     P   PG        G     GLP +A   G
Sbjct: 615 DGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRG 664



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 37/138 (26%), Positives = 46/138 (33%), Gaps = 23/138 (16%)

Query: 124  GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLS 183
            G  G+RG  G PR    A       G      G GP      E         +    P  
Sbjct: 889  GPRGQRGPTG-PRGSRGARGPTGKPGPKGTSGGDGPP-GPPGERGPQGPQGPVGFPGPKG 946

Query: 184  EPDPPARDAASPH-----------QDGAPGPG----PRGGRGQEWRPAPGPAPGQGAEAS 228
             P PP +D    H           + G PGPG    P+G  G+      GP  G+     
Sbjct: 947  PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGET-----GPI-GERGHPG 1000

Query: 229  AQGRAEEEGLPAKAHADG 246
              G   E+GLP  A  +G
Sbjct: 1001 PPGPPGEQGLPGAAGKEG 1018



 Score = 32.3 bits (72), Expect = 1.9
 Identities = 50/179 (27%), Positives = 66/179 (36%), Gaps = 20/179 (11%)

Query: 124 GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLS 183
           G  G RG  GA    +    L  + G+  ED  G P  +G  +     D  E+    P  
Sbjct: 769 GYPGPRGVKGA----DGVRGLKGSKGEKGED--GFPGFKG--DMGLKGDRGEVGQIGPRG 820

Query: 184 EPDPPA-RDAASPHQDGAPGPGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPAKA 242
           E  P   +  A P  D    PGP G  G++ +      PG       QG     G P   
Sbjct: 821 EDGPEGPKGRAGPTGD----PGPSGQAGEKGKLG---VPGLPGYPGRQGPKGSTGFPGFP 873

Query: 243 HADGEPKA-GVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQ-EAPADGMKGPPSGR 299
            A+GE  A GV  +    G+      R S  R  + P   P  +  +  DG  GPP  R
Sbjct: 874 GANGEKGARGVAGKPGPRGQRGPTGPRGS--RGARGPTGKPGPKGTSGGDGPPGPPGER 930



 Score = 32.0 bits (71), Expect = 2.5
 Identities = 35/133 (26%), Positives = 50/133 (37%), Gaps = 7/133 (5%)

Query: 123  AGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSE---LSDT 179
            +G  G  G  G P E  +  A G+      E   G P   G+  E   +  +    L   
Sbjct: 1029 SGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGR 1088

Query: 180  DPLSEPDPPARDAASPHQDGAPGPGPRGG-RGQEWRPAP-GPA--PGQGAEASAQGRAEE 235
                 P  PA +  +P + G  GP  R G +G    P P GPA  PG+  +    G   +
Sbjct: 1089 PGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQ 1148

Query: 236  EGLPAKAHADGEP 248
            +G       +G P
Sbjct: 1149 KGSKGDKGENGPP 1161



 Score = 31.2 bits (69), Expect = 4.2
 Identities = 33/115 (28%), Positives = 37/115 (32%), Gaps = 16/115 (13%)

Query: 124 GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPR-LRGAAEETRDSDLSELSDTDPL 182
           G  G RG AG P             G   +    GPR  RGA   T        S  D  
Sbjct: 877 GEKGARGVAGKP-------------GPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGD-- 921

Query: 183 SEPDPPARDAASPHQDGAPGPGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEG 237
             P PP        Q     PGP+G  G   +      PGQ  E   QG+    G
Sbjct: 922 GPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPG 976



 Score = 30.8 bits (68), Expect = 5.5
 Identities = 36/140 (25%), Positives = 46/140 (32%), Gaps = 11/140 (7%)

Query: 181  PLSEPDPPARDAASPHQDGAPGP----GPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEE 236
            P  +P P          DG PGP    GP+G +G    P P   PG   +    G   + 
Sbjct: 908  PTGKPGPKGTSGG----DGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQR 963

Query: 237  GLPAKAHADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEAPADGMKGPP 296
            G        G P  G     +G      P            P +  L   A  +G KG P
Sbjct: 964  GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP 1023

Query: 297  SGRATKTLESRPLGETLRGF 316
              +     +  P G  LRGF
Sbjct: 1024 GPQGISGKDG-PAG--LRGF 1040


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
            sapiens]
          Length = 1767

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 57/205 (27%), Positives = 72/205 (35%), Gaps = 44/205 (21%)

Query: 122  DAGAGGRRGGAGAPREWNVAYALG-----SATGDDDEDDGGGPRLRGAAEETRDSDLSEL 176
            +AG GG +G  G   E     A G        GDD      GP             +   
Sbjct: 1229 EAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGP-------------VGFP 1275

Query: 177  SDTDPLSEPDPPARDAASPH--QDGAPG-PGPRGGRGQEWRPAPGPAPGQGAEASAQGRA 233
             D  P  EP P  +D       +DG PG PGP G  G+   P P    G    A A+GR 
Sbjct: 1276 GDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQ 1335

Query: 234  EEEGLPAKAHADGEP----------------KAGVRRRRKGVGRHWVPEARASVLRSIQD 277
             E+G   +A A+G P                  G+R     VG   +P A        QD
Sbjct: 1336 GEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAG------QD 1389

Query: 278  PWQGPLVQEAPADGMKGPPSGRATK 302
               GP+       G+KG P  +  K
Sbjct: 1390 GPPGPMGPPG-LPGLKGDPGSKGEK 1413



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 56/189 (29%), Positives = 70/189 (37%), Gaps = 24/189 (12%)

Query: 119  HQCDAGAGGRRGGAGAPREWNVAYALGSA--TGDDDEDDGGGPRLRGAAEETRDSDLSEL 176
            H    G  G +G  G P    V    G    TG   E    GP      +    +   E 
Sbjct: 908  HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEG 967

Query: 177  SDTDP----LSEPDPPARDAASPHQDGAPG----PGPRGGRGQEWRPAPGPAPGQGAEAS 228
            +  DP    +S  D PA     P + G PG    PG +GG G +  P P  +PG   E  
Sbjct: 968  AKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG---ERG 1024

Query: 229  AQGRAEEEGLPAKAHADGEP-KAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEA 287
            + G A   GLP +    G P  AG     KG      P+  A      +D  QGP+    
Sbjct: 1025 SAGTAGPIGLPGRPGPQGPPGPAG----EKGAPGEKGPQGPAG-----RDGVQGPVGLPG 1075

Query: 288  PADGMKGPP 296
            PA G  G P
Sbjct: 1076 PA-GPAGSP 1083



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 55/187 (29%), Positives = 67/187 (35%), Gaps = 20/187 (10%)

Query: 120  QCDAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPR----LRGAAEETRDSDLSE 175
            Q   GA G  GG G P         G   GD+      GP     L+G      +    E
Sbjct: 1116 QGPVGAPGIAGGDGEPGPRGQQGMFGQK-GDEGARGFPGPPGPIGLQGLPGPPGEK--GE 1172

Query: 176  LSDTDPLSEPDPPA-RDAASPH-QDGAPGP----GPRGGRGQEWRPAPGPAPGQGAEASA 229
              D  P+  P PP  R    P+  DG  GP    G  GG G++  P     PG   EA  
Sbjct: 1173 NGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGV 1232

Query: 230  QGRAEEEGLPAKAHADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEAPA 289
             G   E G   +A   G P A      KG      P+     +    DP  GP  +  PA
Sbjct: 1233 GGPKGERGEKGEA---GPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDP--GPPGEPGPA 1287

Query: 290  --DGMKG 294
              DG+ G
Sbjct: 1288 GQDGVGG 1294



 Score = 35.8 bits (81), Expect = 0.17
 Identities = 59/209 (28%), Positives = 72/209 (34%), Gaps = 55/209 (26%)

Query: 122 DAGAGGRRGGAGAPREWNVAYALGSATGDDD---EDDGGGPRLRGAAEETRDSDLSELSD 178
           D G  G RG  G P             GDD    ED   GPR  G   E     L     
Sbjct: 572 DKGHRGERGPQGPP----------GPPGDDGMRGEDGEIGPR--GLPGEAGPRGL----- 614

Query: 179 TDPLSEPDPPARDAASPHQDGAPGP-------GPRGGRGQEWRPAPGPAPG-QG-----A 225
             P   P  P +   +   DG PGP       G  G  GQ+  P P   PG QG      
Sbjct: 615 LGPRGTPGAPGQPGMAG-VDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPG 673

Query: 226 EASAQGRAEEEGLPAKAHADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDPW-QGPLV 284
           E   QG+    GLP    ADG P             H   E ++    ++  P  QGP+ 
Sbjct: 674 EKGPQGKPGLAGLPG---ADGPP------------GHPGKEGQSGEKGALGPPGPQGPIG 718

Query: 285 QEAP-----ADGMKGPPSGRATKTLESRP 308
              P     ADG++G    +  K  +  P
Sbjct: 719 YPGPRGVKGADGVRGLKGSKGEKGEDGFP 747



 Score = 35.8 bits (81), Expect = 0.17
 Identities = 31/129 (24%), Positives = 46/129 (35%), Gaps = 16/129 (12%)

Query: 122  DAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDP 181
            D G+ G +G  G      +   +G      ++ D G P  +G+     D  +       P
Sbjct: 1406 DPGSKGEKGHPG------LIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIP--GPAGP 1457

Query: 182  LSEPDPPARDAASPHQDGAPGPGPRGGRGQEWRPAPGPAPGQGAE--------ASAQGRA 233
            L  P PP        +      GP G +G    P P  +PG   E        +S + R 
Sbjct: 1458 LGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRR 1517

Query: 234  EEEGLPAKA 242
              EG+ A A
Sbjct: 1518 HTEGMQADA 1526



 Score = 35.0 bits (79), Expect = 0.29
 Identities = 33/127 (25%), Positives = 44/127 (34%), Gaps = 10/127 (7%)

Query: 124  GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLS 183
            G+ G RG AG      +    G         + G P  +G         +       P+ 
Sbjct: 1018 GSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQ-----GPVG 1072

Query: 184  EPDPPARDAASPHQDGAPG----PGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLP 239
             P P A  A SP +DG  G    PG +G +G +    P   PG      A G A  +G P
Sbjct: 1073 LPGP-AGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEP 1131

Query: 240  AKAHADG 246
                  G
Sbjct: 1132 GPRGQQG 1138



 Score = 35.0 bits (79), Expect = 0.29
 Identities = 51/190 (26%), Positives = 63/190 (33%), Gaps = 15/190 (7%)

Query: 124  GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGA-AEETRDSDLSELSDTDPL 182
            G GG +G  G P +       G A         G P   GA   +       E     P 
Sbjct: 1291 GVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPP 1350

Query: 183  SEPDP--PARDAASPHQDGAPG-PGP------RGGRGQEWRPAPGPAPGQGAEASAQGRA 233
             +  P  P   A  P  +G  G PGP       G  GQ+  P P   PG        G  
Sbjct: 1351 GKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSK 1410

Query: 234  EEEGLPAKAHADGEP-KAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEAPADGM 292
             E+G P      G P + G +  R   G    P A+      I  P  GPL    P  G+
Sbjct: 1411 GEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGD--GGIPGP-AGPLGPPGP-PGL 1466

Query: 293  KGPPSGRATK 302
             GP   +  K
Sbjct: 1467 PGPQGPKGNK 1476



 Score = 33.5 bits (75), Expect = 0.85
 Identities = 20/57 (35%), Positives = 26/57 (45%), Gaps = 7/57 (12%)

Query: 195 PHQDGAPG----PGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPAKAHADGE 247
           P   GA G    PGP+G RG +  P P   PG+     A G     G+P +  A G+
Sbjct: 507 PGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADG---GRGMPGEPGAKGD 560



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 18/50 (36%), Positives = 21/50 (42%), Gaps = 1/50 (2%)

Query: 198 DGAPG-PGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPAKAHADG 246
           DG PG PG +G RG+     P   PG        G     GLP +A   G
Sbjct: 564 DGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRG 613



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 37/138 (26%), Positives = 46/138 (33%), Gaps = 23/138 (16%)

Query: 124 GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLS 183
           G  G+RG  G PR    A       G      G GP      E         +    P  
Sbjct: 838 GPRGQRGPTG-PRGSRGARGPTGKPGPKGTSGGDGPP-GPPGERGPQGPQGPVGFPGPKG 895

Query: 184 EPDPPARDAASPH-----------QDGAPGPG----PRGGRGQEWRPAPGPAPGQGAEAS 228
            P PP +D    H           + G PGPG    P+G  G+      GP  G+     
Sbjct: 896 PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGET-----GPI-GERGHPG 949

Query: 229 AQGRAEEEGLPAKAHADG 246
             G   E+GLP  A  +G
Sbjct: 950 PPGPPGEQGLPGAAGKEG 967



 Score = 32.3 bits (72), Expect = 1.9
 Identities = 50/179 (27%), Positives = 66/179 (36%), Gaps = 20/179 (11%)

Query: 124 GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLS 183
           G  G RG  GA    +    L  + G+  ED  G P  +G  +     D  E+    P  
Sbjct: 718 GYPGPRGVKGA----DGVRGLKGSKGEKGED--GFPGFKG--DMGLKGDRGEVGQIGPRG 769

Query: 184 EPDPPA-RDAASPHQDGAPGPGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPAKA 242
           E  P   +  A P  D    PGP G  G++ +      PG       QG     G P   
Sbjct: 770 EDGPEGPKGRAGPTGD----PGPSGQAGEKGKLG---VPGLPGYPGRQGPKGSTGFPGFP 822

Query: 243 HADGEPKA-GVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQ-EAPADGMKGPPSGR 299
            A+GE  A GV  +    G+      R S  R  + P   P  +  +  DG  GPP  R
Sbjct: 823 GANGEKGARGVAGKPGPRGQRGPTGPRGS--RGARGPTGKPGPKGTSGGDGPPGPPGER 879



 Score = 32.0 bits (71), Expect = 2.5
 Identities = 35/133 (26%), Positives = 50/133 (37%), Gaps = 7/133 (5%)

Query: 123  AGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSE---LSDT 179
            +G  G  G  G P E  +  A G+      E   G P   G+  E   +  +    L   
Sbjct: 978  SGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGR 1037

Query: 180  DPLSEPDPPARDAASPHQDGAPGPGPRGG-RGQEWRPAP-GPA--PGQGAEASAQGRAEE 235
                 P  PA +  +P + G  GP  R G +G    P P GPA  PG+  +    G   +
Sbjct: 1038 PGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQ 1097

Query: 236  EGLPAKAHADGEP 248
            +G       +G P
Sbjct: 1098 KGSKGDKGENGPP 1110



 Score = 31.2 bits (69), Expect = 4.2
 Identities = 33/115 (28%), Positives = 37/115 (32%), Gaps = 16/115 (13%)

Query: 124 GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPR-LRGAAEETRDSDLSELSDTDPL 182
           G  G RG AG P             G   +    GPR  RGA   T        S  D  
Sbjct: 826 GEKGARGVAGKP-------------GPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGD-- 870

Query: 183 SEPDPPARDAASPHQDGAPGPGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEG 237
             P PP        Q     PGP+G  G   +      PGQ  E   QG+    G
Sbjct: 871 GPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPG 925



 Score = 30.8 bits (68), Expect = 5.5
 Identities = 36/140 (25%), Positives = 46/140 (32%), Gaps = 11/140 (7%)

Query: 181 PLSEPDPPARDAASPHQDGAPGP----GPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEE 236
           P  +P P          DG PGP    GP+G +G    P P   PG   +    G   + 
Sbjct: 857 PTGKPGPKGTSGG----DGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQR 912

Query: 237 GLPAKAHADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEAPADGMKGPP 296
           G        G P  G     +G      P            P +  L   A  +G KG P
Sbjct: 913 GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP 972

Query: 297 SGRATKTLESRPLGETLRGF 316
             +     +  P G  LRGF
Sbjct: 973 GPQGISGKDG-PAG--LRGF 989


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 57/205 (27%), Positives = 72/205 (35%), Gaps = 44/205 (21%)

Query: 122  DAGAGGRRGGAGAPREWNVAYALG-----SATGDDDEDDGGGPRLRGAAEETRDSDLSEL 176
            +AG GG +G  G   E     A G        GDD      GP             +   
Sbjct: 1268 EAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNPGP-------------VGFP 1314

Query: 177  SDTDPLSEPDPPARDAASPH--QDGAPG-PGPRGGRGQEWRPAPGPAPGQGAEASAQGRA 233
             D  P  EP P  +D       +DG PG PGP G  G+   P P    G    A A+GR 
Sbjct: 1315 GDPGPPGEPGPAGQDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQ 1374

Query: 234  EEEGLPAKAHADGEP----------------KAGVRRRRKGVGRHWVPEARASVLRSIQD 277
             E+G   +A A+G P                  G+R     VG   +P A        QD
Sbjct: 1375 GEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAG------QD 1428

Query: 278  PWQGPLVQEAPADGMKGPPSGRATK 302
               GP+       G+KG P  +  K
Sbjct: 1429 GPPGPMGPPG-LPGLKGDPGSKGEK 1452



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 56/189 (29%), Positives = 70/189 (37%), Gaps = 24/189 (12%)

Query: 119  HQCDAGAGGRRGGAGAPREWNVAYALGSA--TGDDDEDDGGGPRLRGAAEETRDSDLSEL 176
            H    G  G +G  G P    V    G    TG   E    GP      +    +   E 
Sbjct: 947  HPGQRGETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEG 1006

Query: 177  SDTDP----LSEPDPPARDAASPHQDGAPG----PGPRGGRGQEWRPAPGPAPGQGAEAS 228
            +  DP    +S  D PA     P + G PG    PG +GG G +  P P  +PG   E  
Sbjct: 1007 AKGDPGPQGISGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPG---ERG 1063

Query: 229  AQGRAEEEGLPAKAHADGEP-KAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEA 287
            + G A   GLP +    G P  AG     KG      P+  A      +D  QGP+    
Sbjct: 1064 SAGTAGPIGLPGRPGPQGPPGPAG----EKGAPGEKGPQGPAG-----RDGVQGPVGLPG 1114

Query: 288  PADGMKGPP 296
            PA G  G P
Sbjct: 1115 PA-GPAGSP 1122



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 55/187 (29%), Positives = 67/187 (35%), Gaps = 20/187 (10%)

Query: 120  QCDAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPR----LRGAAEETRDSDLSE 175
            Q   GA G  GG G P         G   GD+      GP     L+G      +    E
Sbjct: 1155 QGPVGAPGIAGGDGEPGPRGQQGMFGQK-GDEGARGFPGPPGPIGLQGLPGPPGEK--GE 1211

Query: 176  LSDTDPLSEPDPPA-RDAASPH-QDGAPGP----GPRGGRGQEWRPAPGPAPGQGAEASA 229
              D  P+  P PP  R    P+  DG  GP    G  GG G++  P     PG   EA  
Sbjct: 1212 NGDVGPMGPPGPPGPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGV 1271

Query: 230  QGRAEEEGLPAKAHADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEAPA 289
             G   E G   +A   G P A      KG      P+     +    DP  GP  +  PA
Sbjct: 1272 GGPKGERGEKGEA---GPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDP--GPPGEPGPA 1326

Query: 290  --DGMKG 294
              DG+ G
Sbjct: 1327 GQDGVGG 1333



 Score = 35.8 bits (81), Expect = 0.17
 Identities = 59/209 (28%), Positives = 72/209 (34%), Gaps = 55/209 (26%)

Query: 122 DAGAGGRRGGAGAPREWNVAYALGSATGDDD---EDDGGGPRLRGAAEETRDSDLSELSD 178
           D G  G RG  G P             GDD    ED   GPR  G   E     L     
Sbjct: 611 DKGHRGERGPQGPP----------GPPGDDGMRGEDGEIGPR--GLPGEAGPRGL----- 653

Query: 179 TDPLSEPDPPARDAASPHQDGAPGP-------GPRGGRGQEWRPAPGPAPG-QG-----A 225
             P   P  P +   +   DG PGP       G  G  GQ+  P P   PG QG      
Sbjct: 654 LGPRGTPGAPGQPGMAG-VDGPPGPKGNMGPQGEPGPPGQQGNPGPQGLPGPQGPIGPPG 712

Query: 226 EASAQGRAEEEGLPAKAHADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDPW-QGPLV 284
           E   QG+    GLP    ADG P             H   E ++    ++  P  QGP+ 
Sbjct: 713 EKGPQGKPGLAGLPG---ADGPP------------GHPGKEGQSGEKGALGPPGPQGPIG 757

Query: 285 QEAP-----ADGMKGPPSGRATKTLESRP 308
              P     ADG++G    +  K  +  P
Sbjct: 758 YPGPRGVKGADGVRGLKGSKGEKGEDGFP 786



 Score = 35.8 bits (81), Expect = 0.17
 Identities = 31/129 (24%), Positives = 46/129 (35%), Gaps = 16/129 (12%)

Query: 122  DAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDP 181
            D G+ G +G  G      +   +G      ++ D G P  +G+     D  +       P
Sbjct: 1445 DPGSKGEKGHPG------LIGLIGPPGEQGEKGDRGLPGTQGSPGAKGDGGIP--GPAGP 1496

Query: 182  LSEPDPPARDAASPHQDGAPGPGPRGGRGQEWRPAPGPAPGQGAE--------ASAQGRA 233
            L  P PP        +      GP G +G    P P  +PG   E        +S + R 
Sbjct: 1497 LGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEVIQPLPILSSKKTRR 1556

Query: 234  EEEGLPAKA 242
              EG+ A A
Sbjct: 1557 HTEGMQADA 1565



 Score = 35.0 bits (79), Expect = 0.29
 Identities = 33/127 (25%), Positives = 44/127 (34%), Gaps = 10/127 (7%)

Query: 124  GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLS 183
            G+ G RG AG      +    G         + G P  +G         +       P+ 
Sbjct: 1057 GSPGERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQ-----GPVG 1111

Query: 184  EPDPPARDAASPHQDGAPG----PGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLP 239
             P P A  A SP +DG  G    PG +G +G +    P   PG      A G A  +G P
Sbjct: 1112 LPGP-AGPAGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEP 1170

Query: 240  AKAHADG 246
                  G
Sbjct: 1171 GPRGQQG 1177



 Score = 35.0 bits (79), Expect = 0.29
 Identities = 51/190 (26%), Positives = 63/190 (33%), Gaps = 15/190 (7%)

Query: 124  GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGA-AEETRDSDLSELSDTDPL 182
            G GG +G  G P +       G A         G P   GA   +       E     P 
Sbjct: 1330 GVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPPGAAGAEGRQGEKGAKGEAGAEGPP 1389

Query: 183  SEPDP--PARDAASPHQDGAPG-PGP------RGGRGQEWRPAPGPAPGQGAEASAQGRA 233
             +  P  P   A  P  +G  G PGP       G  GQ+  P P   PG        G  
Sbjct: 1390 GKTGPVGPQGPAGKPGPEGLRGIPGPVGEQGLPGAAGQDGPPGPMGPPGLPGLKGDPGSK 1449

Query: 234  EEEGLPAKAHADGEP-KAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEAPADGM 292
             E+G P      G P + G +  R   G    P A+      I  P  GPL    P  G+
Sbjct: 1450 GEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPGAKGD--GGIPGP-AGPLGPPGP-PGL 1505

Query: 293  KGPPSGRATK 302
             GP   +  K
Sbjct: 1506 PGPQGPKGNK 1515



 Score = 33.5 bits (75), Expect = 0.85
 Identities = 20/57 (35%), Positives = 26/57 (45%), Gaps = 7/57 (12%)

Query: 195 PHQDGAPG----PGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPAKAHADGE 247
           P   GA G    PGP+G RG +  P P   PG+     A G     G+P +  A G+
Sbjct: 546 PGSSGAKGESGDPGPQGPRGVQGPPGPTGKPGKRGRPGADG---GRGMPGEPGAKGD 599



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 18/50 (36%), Positives = 21/50 (42%), Gaps = 1/50 (2%)

Query: 198 DGAPG-PGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPAKAHADG 246
           DG PG PG +G RG+     P   PG        G     GLP +A   G
Sbjct: 603 DGLPGLPGDKGHRGERGPQGPPGPPGDDGMRGEDGEIGPRGLPGEAGPRG 652



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 37/138 (26%), Positives = 46/138 (33%), Gaps = 23/138 (16%)

Query: 124  GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLS 183
            G  G+RG  G PR    A       G      G GP      E         +    P  
Sbjct: 877  GPRGQRGPTG-PRGSRGARGPTGKPGPKGTSGGDGPP-GPPGERGPQGPQGPVGFPGPKG 934

Query: 184  EPDPPARDAASPH-----------QDGAPGPG----PRGGRGQEWRPAPGPAPGQGAEAS 228
             P PP +D    H           + G PGPG    P+G  G+      GP  G+     
Sbjct: 935  PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGGVVGPQGPTGET-----GPI-GERGHPG 988

Query: 229  AQGRAEEEGLPAKAHADG 246
              G   E+GLP  A  +G
Sbjct: 989  PPGPPGEQGLPGAAGKEG 1006



 Score = 32.3 bits (72), Expect = 1.9
 Identities = 50/179 (27%), Positives = 66/179 (36%), Gaps = 20/179 (11%)

Query: 124 GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLS 183
           G  G RG  GA    +    L  + G+  ED  G P  +G  +     D  E+    P  
Sbjct: 757 GYPGPRGVKGA----DGVRGLKGSKGEKGED--GFPGFKG--DMGLKGDRGEVGQIGPRG 808

Query: 184 EPDPPA-RDAASPHQDGAPGPGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPAKA 242
           E  P   +  A P  D    PGP G  G++ +      PG       QG     G P   
Sbjct: 809 EDGPEGPKGRAGPTGD----PGPSGQAGEKGKLG---VPGLPGYPGRQGPKGSTGFPGFP 861

Query: 243 HADGEPKA-GVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQ-EAPADGMKGPPSGR 299
            A+GE  A GV  +    G+      R S  R  + P   P  +  +  DG  GPP  R
Sbjct: 862 GANGEKGARGVAGKPGPRGQRGPTGPRGS--RGARGPTGKPGPKGTSGGDGPPGPPGER 918



 Score = 32.0 bits (71), Expect = 2.5
 Identities = 35/133 (26%), Positives = 50/133 (37%), Gaps = 7/133 (5%)

Query: 123  AGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSE---LSDT 179
            +G  G  G  G P E  +  A G+      E   G P   G+  E   +  +    L   
Sbjct: 1017 SGKDGPAGLRGFPGERGLPGAQGAPGLKGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGR 1076

Query: 180  DPLSEPDPPARDAASPHQDGAPGPGPRGG-RGQEWRPAP-GPA--PGQGAEASAQGRAEE 235
                 P  PA +  +P + G  GP  R G +G    P P GPA  PG+  +    G   +
Sbjct: 1077 PGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPAGPAGSPGEDGDKGEIGEPGQ 1136

Query: 236  EGLPAKAHADGEP 248
            +G       +G P
Sbjct: 1137 KGSKGDKGENGPP 1149



 Score = 31.2 bits (69), Expect = 4.2
 Identities = 33/115 (28%), Positives = 37/115 (32%), Gaps = 16/115 (13%)

Query: 124 GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPR-LRGAAEETRDSDLSELSDTDPL 182
           G  G RG AG P             G   +    GPR  RGA   T        S  D  
Sbjct: 865 GEKGARGVAGKP-------------GPRGQRGPTGPRGSRGARGPTGKPGPKGTSGGD-- 909

Query: 183 SEPDPPARDAASPHQDGAPGPGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEG 237
             P PP        Q     PGP+G  G   +      PGQ  E   QG+    G
Sbjct: 910 GPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPG 964



 Score = 30.8 bits (68), Expect = 5.5
 Identities = 36/140 (25%), Positives = 46/140 (32%), Gaps = 11/140 (7%)

Query: 181  PLSEPDPPARDAASPHQDGAPGP----GPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEE 236
            P  +P P          DG PGP    GP+G +G    P P   PG   +    G   + 
Sbjct: 896  PTGKPGPKGTSGG----DGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQR 951

Query: 237  GLPAKAHADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEAPADGMKGPP 296
            G        G P  G     +G      P            P +  L   A  +G KG P
Sbjct: 952  GETGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGAAGKEGAKGDP 1011

Query: 297  SGRATKTLESRPLGETLRGF 316
              +     +  P G  LRGF
Sbjct: 1012 GPQGISGKDG-PAG--LRGF 1028


>gi|12707580 paired-like homeobox 2b [Homo sapiens]
          Length = 314

 Score = 48.5 bits (114), Expect = 3e-05
 Identities = 39/123 (31%), Positives = 50/123 (40%), Gaps = 13/123 (10%)

Query: 165 AEETRDSDLSELSDTDPLSE----PDPPARDAASPHQDGAPGPGPRGGRGQEWRPAPGPA 220
           ++ +RD +  E   TDP S     P+P    +   +  G  GP P G  G      PG  
Sbjct: 176 SDSSRDDESKEAKSTDPDSTGGPGPNPNPTPSCGANGGGGGGPSPAGAPGAAGPGGPGGE 235

Query: 221 PGQ-GAEASAQGRAEEEGLPAKAHADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDPW 279
           PG+ GA A+A   A      A A A G   AG      G G+ W P      + SI D  
Sbjct: 236 PGKGGAAAAAAAAAAAAAAAAAAAAGGLAAAG------GPGQGWAP--GPGPITSIPDSL 287

Query: 280 QGP 282
            GP
Sbjct: 288 GGP 290


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 41/126 (32%), Positives = 50/126 (39%), Gaps = 13/126 (10%)

Query: 124 GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLS 183
           G  G  G  GAP E   +   G    + D    G P L GA   T         D  P  
Sbjct: 519 GQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLT-----GRPGDAGPQG 573

Query: 184 EPDPPARDAASPHQDGAPGP-GPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPAKA 242
           +  P    + +P +DG PGP GP+G RGQ   P     PG        G+A E+GLP   
Sbjct: 574 KVGP----SGAPGEDGRPGPPGPQGARGQ---PGVMGFPGPKGANGEPGKAGEKGLPGAP 626

Query: 243 HADGEP 248
              G P
Sbjct: 627 GLRGLP 632



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 46/144 (31%), Positives = 56/144 (38%), Gaps = 21/144 (14%)

Query: 119 HQCDAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPR-LRGAAEETRDSDLSELS 177
           H+   G  G +G AGAP    V    GS  G++      GPR L G    T  +  +   
Sbjct: 289 HRGYPGLDGAKGEAGAP---GVKGESGSP-GENGSPGPMGPRGLPGERGRTGPAGAAGAR 344

Query: 178 DTDPLSEPDP-----PARDAASPHQDGAPGP----GPRGGRGQEW----RPAPGPAPGQG 224
             D   +P P     P   A  P   GAPG     GP G RG E     R  PG  PG  
Sbjct: 345 GND--GQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPG-TPGSP 401

Query: 225 AEASAQGRAEEEGLPAKAHADGEP 248
             A A G    +G+P    + G P
Sbjct: 402 GPAGASGNPGTDGIPGAKGSAGAP 425



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 55/204 (26%), Positives = 72/204 (35%), Gaps = 37/204 (18%)

Query: 123 AGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEET--RDSDLSELSDTD 180
           AGA G RG  G P        +G A G       G P  +G A  T  R  + ++    +
Sbjct: 338 AGAAGARGNDGQPGPAGPPGPVGPAGGPGFP---GAPGAKGEAGPTGARGPEGAQGPRGE 394

Query: 181 PLSEPDP-PARDAASPHQDGAPG----------------------PGPRGG------RGQ 211
           P +   P PA  + +P  DG PG                      PGP+G       +GQ
Sbjct: 395 PGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQ 454

Query: 212 EWRPAPGPAPGQGAEASAQGRAEEEGLPAKAHADGEPKAGVRRRRKGVGRHWVPEARASV 271
              P      G+       G A  +G P  A  +G  K G R    GVG    P  R + 
Sbjct: 455 TGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEG--KRGARGEPGGVGPIGPPGERGAP 512

Query: 272 LRSIQDPWQGPLVQEAPADGMKGP 295
             +   P Q  L     A G +GP
Sbjct: 513 -GNRGFPGQDGLAGPKGAPGERGP 535



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 39/148 (26%), Positives = 47/148 (31%), Gaps = 23/148 (15%)

Query: 122  DAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDP 181
            DAGA G +G +GAP         G       +   G     GAA   R        +  P
Sbjct: 859  DAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAG--RVGPPGSNGNPGP 916

Query: 182  LSEPDPPARD--------AASPHQDGAPG-------------PGPRGGRGQEWRPAPGPA 220
               P P  +D        +  P + G PG             PG  G  G E  P P   
Sbjct: 917  PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGL 976

Query: 221  PGQGAEASAQGRAEEEGLPAKAHADGEP 248
             GQ       G+  E G P      GEP
Sbjct: 977  AGQRGIVGLPGQRGERGFPGLPGPSGEP 1004



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 59/225 (26%), Positives = 72/225 (32%), Gaps = 35/225 (15%)

Query: 124  GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLS 183
            G+ G  G  G P         G+          G P L+G A    +    E  D  P  
Sbjct: 909  GSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEK--GEPGDDGPSG 966

Query: 184  EPDPPARDAASPHQDGAPGPGPRGGRGQEWRPAPGPAPG-QGAEASA------------- 229
               PP     +  +     PG RG RG    P P   PG QGA  ++             
Sbjct: 967  AEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPG 1026

Query: 230  -QGRAEEEGLPAKAHADGEP----KAGVRRRRKGVGRHWVPEA--------RASVLRSIQ 276
              G A E G      ADG P     AGV+  R   G    P A         A       
Sbjct: 1027 LTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG 1086

Query: 277  DPW----QGPLVQEAPAD--GMKGPPSGRATKTLESRPLGETLRG 315
            D      QGP+    PA   G++GP   R  K     P    L+G
Sbjct: 1087 DRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKG 1131



 Score = 38.1 bits (87), Expect = 0.035
 Identities = 26/69 (37%), Positives = 29/69 (42%), Gaps = 5/69 (7%)

Query: 181 PLSEPDPPARDAASPHQDGAPG-PGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLP 239
           P   P P      +P + G PG  GP G RG    P P   PG   EA   G+A E G P
Sbjct: 214 PAGAPGPQGFQG-NPGEPGEPGVSGPMGPRGP---PGPPGKPGDDGEAGKPGKAGERGPP 269

Query: 240 AKAHADGEP 248
               A G P
Sbjct: 270 GPQGARGFP 278



 Score = 38.1 bits (87), Expect = 0.035
 Identities = 38/144 (26%), Positives = 49/144 (34%), Gaps = 19/144 (13%)

Query: 122 DAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDP 181
           DAG  G+ G +GAP E       G           G P  +GA  E   +    L     
Sbjct: 568 DAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPG 627

Query: 182 L------------SEPDPPARDAASPHQDGAPGP-------GPRGGRGQEWRPAPGPAPG 222
           L            + P  PA  A    + GAPGP       GP G  G+  +P     PG
Sbjct: 628 LRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPG 687

Query: 223 QGAEASAQGRAEEEGLPAKAHADG 246
           +       G   E G P +  + G
Sbjct: 688 EAGAPGLVGPRGERGFPGERGSPG 711



 Score = 37.7 bits (86), Expect = 0.045
 Identities = 53/190 (27%), Positives = 70/190 (36%), Gaps = 24/190 (12%)

Query: 124 GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLS-ELSDTDPL 182
           GA G +G  G P         G++         G P L+G   E   + ++    D   +
Sbjct: 711 GAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV 770

Query: 183 SEPDPPARDAASPHQDGAPG-------PGPRGGRGQEWRPA-PGPAPGQGAEASAQGRAE 234
            E  P      +P +DG  G       PGP G  G++     PGPA   GA   A G   
Sbjct: 771 GEKGPEG----APGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGAR-GAPGERG 825

Query: 235 EEGLPAKA------HADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEAP 288
           E G P  A       ADG+P  G +  +   G+     A      S     QGP     P
Sbjct: 826 ETGPPGPAGFAGPPGADGQP--GAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGP 883

Query: 289 --ADGMKGPP 296
             A G +GPP
Sbjct: 884 KGARGAQGPP 893



 Score = 36.6 bits (83), Expect = 0.10
 Identities = 35/134 (26%), Positives = 42/134 (31%), Gaps = 1/134 (0%)

Query: 120  QCDAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDT 179
            Q D G  G +G  G           G      D+ + G P  RG       + L  L   
Sbjct: 1085 QGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGP 1144

Query: 180  DPLSEPDPPARDAASPHQDGAPGP-GPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGL 238
               S     +  A      G PGP GP G  G    P P   PG    +   G A   G 
Sbjct: 1145 PGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGN 1204

Query: 239  PAKAHADGEPKAGV 252
            P      G P  G+
Sbjct: 1205 PGPPGPPGPPGPGI 1218



 Score = 35.0 bits (79), Expect = 0.29
 Identities = 54/199 (27%), Positives = 62/199 (31%), Gaps = 30/199 (15%)

Query: 124 GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLS 183
           GA G+ GG G           G A G+  E    GP    A       +  E     P  
Sbjct: 777 GAPGKDGGRGLTGPIGPPGPAG-ANGEKGEVGPPGPA-GSAGARGAPGERGETGPPGPAG 834

Query: 184 EPDPPARD-----------AASPHQDGAPGP-GPRGGRGQEW----------RPAPGPAP 221
              PP  D           A      GAPGP GP G  G +           R A GP P
Sbjct: 835 FAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP-P 893

Query: 222 GQGAEASAQGRAEEEGLPAKAHADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDPWQG 281
           G      A GR    G        G P    +   KG      P  RA     +Q P   
Sbjct: 894 GATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE-PGLQGPAGP 952

Query: 282 PLVQEAPAD----GMKGPP 296
           P  +  P D    G +GPP
Sbjct: 953 PGEKGEPGDDGPSGAEGPP 971



 Score = 33.9 bits (76), Expect = 0.65
 Identities = 41/156 (26%), Positives = 52/156 (33%), Gaps = 28/156 (17%)

Query: 123 AGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAE------ETRDSDLSEL 176
           AGA G  G  G P     A A G A         G P  +GA        +T +  ++  
Sbjct: 404 AGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGF 463

Query: 177 S-DTDPLSEPDP--------PARDAASPHQDGAPG-------------PGPRGGRGQEWR 214
             +  P  EP P        PA +       G PG             PG RG  GQ+  
Sbjct: 464 KGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGL 523

Query: 215 PAPGPAPGQGAEASAQGRAEEEGLPAKAHADGEPKA 250
             P  APG+   +   G     G P +    G P A
Sbjct: 524 AGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGA 559



 Score = 32.3 bits (72), Expect = 1.9
 Identities = 22/74 (29%), Positives = 26/74 (35%), Gaps = 6/74 (8%)

Query: 181 PLSEPDPPAR-----DAASPHQDGAPGP-GPRGGRGQEWRPAPGPAPGQGAEASAQGRAE 234
           P   P PP +     +A  P + G  GP GP+G RG    P      G        G   
Sbjct: 241 PRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKG 300

Query: 235 EEGLPAKAHADGEP 248
           E G P      G P
Sbjct: 301 EAGAPGVKGESGSP 314



 Score = 30.4 bits (67), Expect = 7.2
 Identities = 34/134 (25%), Positives = 40/134 (29%), Gaps = 20/134 (14%)

Query: 130 GGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLSEPDPP- 188
           G  G P     A   G      D+ + G P  RG     RD +     +  P   P PP 
Sbjct: 117 GPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRG-----RDGEPGTPGNPGPPGPPGPPG 171

Query: 189 --------ARDAASPHQDGAPGP------GPRGGRGQEWRPAPGPAPGQGAEASAQGRAE 234
                   A   A    + A G       GP G  G    P P  APG        G   
Sbjct: 172 PPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPG 231

Query: 235 EEGLPAKAHADGEP 248
           E G+       G P
Sbjct: 232 EPGVSGPMGPRGPP 245



 Score = 30.4 bits (67), Expect = 7.2
 Identities = 32/115 (27%), Positives = 40/115 (34%), Gaps = 14/115 (12%)

Query: 124  GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLS 183
            G  G +G AG P E  +    G  TG        GP    + ++             P  
Sbjct: 1113 GPRGDKGEAGEPGERGLKGHRGF-TGLQGLPGPPGP----SGDQGASGPAGPSGPRGPPG 1167

Query: 184  EPDPPARDAAS--PHQDGAPGP-------GPRGGRGQEWRPAPGPAPGQGAEASA 229
               P  +D A+  P   G PGP       GP G  G    P P   PG G + SA
Sbjct: 1168 PVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSA 1222


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 41/126 (32%), Positives = 50/126 (39%), Gaps = 13/126 (10%)

Query: 124 GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLS 183
           G  G  G  GAP E   +   G    + D    G P L GA   T         D  P  
Sbjct: 450 GQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLT-----GRPGDAGPQG 504

Query: 184 EPDPPARDAASPHQDGAPGP-GPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPAKA 242
           +  P    + +P +DG PGP GP+G RGQ   P     PG        G+A E+GLP   
Sbjct: 505 KVGP----SGAPGEDGRPGPPGPQGARGQ---PGVMGFPGPKGANGEPGKAGEKGLPGAP 557

Query: 243 HADGEP 248
              G P
Sbjct: 558 GLRGLP 563



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 46/144 (31%), Positives = 56/144 (38%), Gaps = 21/144 (14%)

Query: 119 HQCDAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPR-LRGAAEETRDSDLSELS 177
           H+   G  G +G AGAP    V    GS  G++      GPR L G    T  +  +   
Sbjct: 220 HRGYPGLDGAKGEAGAP---GVKGESGSP-GENGSPGPMGPRGLPGERGRTGPAGAAGAR 275

Query: 178 DTDPLSEPDP-----PARDAASPHQDGAPGP----GPRGGRGQEW----RPAPGPAPGQG 224
             D   +P P     P   A  P   GAPG     GP G RG E     R  PG  PG  
Sbjct: 276 GND--GQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPG-TPGSP 332

Query: 225 AEASAQGRAEEEGLPAKAHADGEP 248
             A A G    +G+P    + G P
Sbjct: 333 GPAGASGNPGTDGIPGAKGSAGAP 356



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 55/204 (26%), Positives = 72/204 (35%), Gaps = 37/204 (18%)

Query: 123 AGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEET--RDSDLSELSDTD 180
           AGA G RG  G P        +G A G       G P  +G A  T  R  + ++    +
Sbjct: 269 AGAAGARGNDGQPGPAGPPGPVGPAGGPGFP---GAPGAKGEAGPTGARGPEGAQGPRGE 325

Query: 181 PLSEPDP-PARDAASPHQDGAPG----------------------PGPRGG------RGQ 211
           P +   P PA  + +P  DG PG                      PGP+G       +GQ
Sbjct: 326 PGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQ 385

Query: 212 EWRPAPGPAPGQGAEASAQGRAEEEGLPAKAHADGEPKAGVRRRRKGVGRHWVPEARASV 271
              P      G+       G A  +G P  A  +G  K G R    GVG    P  R + 
Sbjct: 386 TGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEG--KRGARGEPGGVGPIGPPGERGAP 443

Query: 272 LRSIQDPWQGPLVQEAPADGMKGP 295
             +   P Q  L     A G +GP
Sbjct: 444 -GNRGFPGQDGLAGPKGAPGERGP 466



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 39/148 (26%), Positives = 47/148 (31%), Gaps = 23/148 (15%)

Query: 122 DAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDP 181
           DAGA G +G +GAP         G       +   G     GAA   R        +  P
Sbjct: 790 DAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGFPGAAG--RVGPPGSNGNPGP 847

Query: 182 LSEPDPPARD--------AASPHQDGAPG-------------PGPRGGRGQEWRPAPGPA 220
              P P  +D        +  P + G PG             PG  G  G E  P P   
Sbjct: 848 PGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGL 907

Query: 221 PGQGAEASAQGRAEEEGLPAKAHADGEP 248
            GQ       G+  E G P      GEP
Sbjct: 908 AGQRGIVGLPGQRGERGFPGLPGPSGEP 935



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 59/225 (26%), Positives = 72/225 (32%), Gaps = 35/225 (15%)

Query: 124  GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLS 183
            G+ G  G  G P         G+          G P L+G A    +    E  D  P  
Sbjct: 840  GSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEK--GEPGDDGPSG 897

Query: 184  EPDPPARDAASPHQDGAPGPGPRGGRGQEWRPAPGPAPG-QGAEASA------------- 229
               PP     +  +     PG RG RG    P P   PG QGA  ++             
Sbjct: 898  AEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPG 957

Query: 230  -QGRAEEEGLPAKAHADGEP----KAGVRRRRKGVGRHWVPEA--------RASVLRSIQ 276
              G A E G      ADG P     AGV+  R   G    P A         A       
Sbjct: 958  LTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG 1017

Query: 277  DPW----QGPLVQEAPAD--GMKGPPSGRATKTLESRPLGETLRG 315
            D      QGP+    PA   G++GP   R  K     P    L+G
Sbjct: 1018 DRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKG 1062



 Score = 38.1 bits (87), Expect = 0.035
 Identities = 26/69 (37%), Positives = 29/69 (42%), Gaps = 5/69 (7%)

Query: 181 PLSEPDPPARDAASPHQDGAPG-PGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLP 239
           P   P P      +P + G PG  GP G RG    P P   PG   EA   G+A E G P
Sbjct: 145 PAGAPGPQGFQG-NPGEPGEPGVSGPMGPRGP---PGPPGKPGDDGEAGKPGKAGERGPP 200

Query: 240 AKAHADGEP 248
               A G P
Sbjct: 201 GPQGARGFP 209



 Score = 38.1 bits (87), Expect = 0.035
 Identities = 38/144 (26%), Positives = 49/144 (34%), Gaps = 19/144 (13%)

Query: 122 DAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDP 181
           DAG  G+ G +GAP E       G           G P  +GA  E   +    L     
Sbjct: 499 DAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPKGANGEPGKAGEKGLPGAPG 558

Query: 182 L------------SEPDPPARDAASPHQDGAPGP-------GPRGGRGQEWRPAPGPAPG 222
           L            + P  PA  A    + GAPGP       GP G  G+  +P     PG
Sbjct: 559 LRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPG 618

Query: 223 QGAEASAQGRAEEEGLPAKAHADG 246
           +       G   E G P +  + G
Sbjct: 619 EAGAPGLVGPRGERGFPGERGSPG 642



 Score = 37.7 bits (86), Expect = 0.045
 Identities = 53/190 (27%), Positives = 70/190 (36%), Gaps = 24/190 (12%)

Query: 124 GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLS-ELSDTDPL 182
           GA G +G  G P         G++         G P L+G   E   + ++    D   +
Sbjct: 642 GAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV 701

Query: 183 SEPDPPARDAASPHQDGAPG-------PGPRGGRGQEWRPA-PGPAPGQGAEASAQGRAE 234
            E  P      +P +DG  G       PGP G  G++     PGPA   GA   A G   
Sbjct: 702 GEKGPEG----APGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGAR-GAPGERG 756

Query: 235 EEGLPAKA------HADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEAP 288
           E G P  A       ADG+P  G +  +   G+     A      S     QGP     P
Sbjct: 757 ETGPPGPAGFAGPPGADGQP--GAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGP 814

Query: 289 --ADGMKGPP 296
             A G +GPP
Sbjct: 815 KGARGAQGPP 824



 Score = 36.6 bits (83), Expect = 0.10
 Identities = 35/134 (26%), Positives = 42/134 (31%), Gaps = 1/134 (0%)

Query: 120  QCDAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDT 179
            Q D G  G +G  G           G      D+ + G P  RG       + L  L   
Sbjct: 1016 QGDRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGP 1075

Query: 180  DPLSEPDPPARDAASPHQDGAPGP-GPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGL 238
               S     +  A      G PGP GP G  G    P P   PG    +   G A   G 
Sbjct: 1076 PGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGN 1135

Query: 239  PAKAHADGEPKAGV 252
            P      G P  G+
Sbjct: 1136 PGPPGPPGPPGPGI 1149



 Score = 35.0 bits (79), Expect = 0.29
 Identities = 54/199 (27%), Positives = 62/199 (31%), Gaps = 30/199 (15%)

Query: 124 GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLS 183
           GA G+ GG G           G A G+  E    GP    A       +  E     P  
Sbjct: 708 GAPGKDGGRGLTGPIGPPGPAG-ANGEKGEVGPPGPA-GSAGARGAPGERGETGPPGPAG 765

Query: 184 EPDPPARD-----------AASPHQDGAPGP-GPRGGRGQEW----------RPAPGPAP 221
              PP  D           A      GAPGP GP G  G +           R A GP P
Sbjct: 766 FAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGP-P 824

Query: 222 GQGAEASAQGRAEEEGLPAKAHADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDPWQG 281
           G      A GR    G        G P    +   KG      P  RA     +Q P   
Sbjct: 825 GATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE-PGLQGPAGP 883

Query: 282 PLVQEAPAD----GMKGPP 296
           P  +  P D    G +GPP
Sbjct: 884 PGEKGEPGDDGPSGAEGPP 902



 Score = 33.9 bits (76), Expect = 0.65
 Identities = 41/156 (26%), Positives = 52/156 (33%), Gaps = 28/156 (17%)

Query: 123 AGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAE------ETRDSDLSEL 176
           AGA G  G  G P     A A G A         G P  +GA        +T +  ++  
Sbjct: 335 AGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGF 394

Query: 177 S-DTDPLSEPDP--------PARDAASPHQDGAPG-------------PGPRGGRGQEWR 214
             +  P  EP P        PA +       G PG             PG RG  GQ+  
Sbjct: 395 KGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGERGAPGNRGFPGQDGL 454

Query: 215 PAPGPAPGQGAEASAQGRAEEEGLPAKAHADGEPKA 250
             P  APG+   +   G     G P +    G P A
Sbjct: 455 AGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGA 490



 Score = 32.3 bits (72), Expect = 1.9
 Identities = 22/74 (29%), Positives = 26/74 (35%), Gaps = 6/74 (8%)

Query: 181 PLSEPDPPAR-----DAASPHQDGAPGP-GPRGGRGQEWRPAPGPAPGQGAEASAQGRAE 234
           P   P PP +     +A  P + G  GP GP+G RG    P      G        G   
Sbjct: 172 PRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKG 231

Query: 235 EEGLPAKAHADGEP 248
           E G P      G P
Sbjct: 232 EAGAPGVKGESGSP 245



 Score = 30.4 bits (67), Expect = 7.2
 Identities = 34/134 (25%), Positives = 40/134 (29%), Gaps = 20/134 (14%)

Query: 130 GGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLSEPDPP- 188
           G  G P     A   G      D+ + G P  RG     RD +     +  P   P PP 
Sbjct: 48  GPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRG-----RDGEPGTPGNPGPPGPPGPPG 102

Query: 189 --------ARDAASPHQDGAPGP------GPRGGRGQEWRPAPGPAPGQGAEASAQGRAE 234
                   A   A    + A G       GP G  G    P P  APG        G   
Sbjct: 103 PPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPG 162

Query: 235 EEGLPAKAHADGEP 248
           E G+       G P
Sbjct: 163 EPGVSGPMGPRGPP 176



 Score = 30.4 bits (67), Expect = 7.2
 Identities = 32/115 (27%), Positives = 40/115 (34%), Gaps = 14/115 (12%)

Query: 124  GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLS 183
            G  G +G AG P E  +    G  TG        GP    + ++             P  
Sbjct: 1044 GPRGDKGEAGEPGERGLKGHRGF-TGLQGLPGPPGP----SGDQGASGPAGPSGPRGPPG 1098

Query: 184  EPDPPARDAAS--PHQDGAPGP-------GPRGGRGQEWRPAPGPAPGQGAEASA 229
               P  +D A+  P   G PGP       GP G  G    P P   PG G + SA
Sbjct: 1099 PVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSA 1153


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 42/128 (32%), Positives = 52/128 (40%), Gaps = 13/128 (10%)

Query: 122 DAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDP 181
           + GA G +G  G P E      +G      +    G P L GAA   R +D +  SD   
Sbjct: 277 ETGAPGLKGENGLPGENGAPGPMGPRGAPGER---GRPGLPGAAG-ARGNDGARGSD--- 329

Query: 182 LSEPDPPARDAASPHQDGAPG-PGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPA 240
             +P PP      P   G PG PG +G  G    P    APGQ  E   QG A  +G P 
Sbjct: 330 -GQPGPPG----PPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPG 384

Query: 241 KAHADGEP 248
               +G P
Sbjct: 385 PPGINGSP 392



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 59/201 (29%), Positives = 65/201 (32%), Gaps = 22/201 (10%)

Query: 123 AGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPL 182
           AGA G RGGAG P         G+A         G P L+G   E     L         
Sbjct: 689 AGAPGLRGGAGPP---GPEGGKGAAGPPGPPGAAGTPGLQGMPGER--GGLGSPGPKGDK 743

Query: 183 SEPDPPARDAASPHQDGAPGP----GPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGL 238
            EP  P  D   P +DG  GP    GP G  GQ      G APG    A  +G   E G 
Sbjct: 744 GEPGGPGADGV-PGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGE 802

Query: 239 PAKAHADGEPKA-GVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEAP--ADGMKGP 295
                  G P A G      G G    P  +            GP     P    G  GP
Sbjct: 803 TGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGE---------GGPPGVAGPPGGSGPAGP 853

Query: 296 PSGRATKTLESRPLGETLRGF 316
           P  +  K     P G    GF
Sbjct: 854 PGPQGVKGERGSPGGPGAAGF 874



 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 53/181 (29%), Positives = 66/181 (36%), Gaps = 21/181 (11%)

Query: 124 GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLS 183
           GA G  G  G P E      LGS     D+ + GGP   G   +           T P+ 
Sbjct: 717 GAAGTPGLQGMPGERG---GLGSPGPKGDKGEPGGPGADGVPGKD-----GPRGPTGPIG 768

Query: 184 EPDPPARDAASPHQDGAPG----PGPRGG---RGQEWRPAPGPAPGQGAEASAQGRAEEE 236
            P P A       + GAPG     GPRG    RG+   P P   PG   +    G   E 
Sbjct: 769 PPGP-AGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGER 827

Query: 237 GLPAKAHADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEAP-ADGMKGP 295
           G P +    G P  GV     G G    P  +   ++  +    GP     P A G+ GP
Sbjct: 828 GAPGEKGEGGPP--GVAGPPGGSGPAGPPGPQG--VKGERGSPGGPGAAGFPGARGLPGP 883

Query: 296 P 296
           P
Sbjct: 884 P 884



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 36/134 (26%), Positives = 47/134 (35%), Gaps = 11/134 (8%)

Query: 124 GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLS 183
           G GG +G  G P    +    G+     +    G P  +G A            D     
Sbjct: 624 GPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAP--GGKGDAGAPG 681

Query: 184 EPDPPARDAASPHQDGAPGPGPRGGRGQEWRPAPGPA---------PGQGAEASAQGRAE 234
           E  PP    A   + GA  PGP GG+G    P P  A         PG+     + G   
Sbjct: 682 ERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKG 741

Query: 235 EEGLPAKAHADGEP 248
           ++G P    ADG P
Sbjct: 742 DKGEPGGPGADGVP 755



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 52/190 (27%), Positives = 73/190 (38%), Gaps = 30/190 (15%)

Query: 192 AASPHQDGAPG-PGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPAKAHADGEP-- 248
           A  P ++GA G PGPRG RG+   P    A G+  +  + G     GLP  A   G P  
Sbjct: 431 AGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGF 490

Query: 249 -----KAGVRRRRKGVGRHWVPEARASVLRSIQDPWQ-----GPLVQEAP-------ADG 291
                  G+   +   G    P   A    +  +P +     GP ++  P       +DG
Sbjct: 491 RGPAGPNGIPGEKGPAGERGAP-GPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDG 549

Query: 292 MKGPP-----SGRATKTLESRPLGET-LRGFCTSEDSDINITSGEEDHKEQP-FPGVCNP 344
             GPP     SGR      S P G+  + GF   + +D     G+   +  P  PG   P
Sbjct: 550 KPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGND--GAPGKNGERGGPGGPGPQGP 607

Query: 345 KEKNSGRVPR 354
             KN    P+
Sbjct: 608 PGKNGETGPQ 617



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 48/190 (25%), Positives = 57/190 (30%), Gaps = 19/190 (10%)

Query: 123  AGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPL 182
            AG  G  G  G P    +    GS  G  D  + G P   GA                  
Sbjct: 1004 AGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPG---------- 1053

Query: 183  SEPDPPARDAASPHQDGAPGP----GPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGL 238
              P  PA  +    + G  GP    GP G RG      P    G+  E  A G     G 
Sbjct: 1054 --PVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGF 1111

Query: 239  PAKAHADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEAPADGMKGPPSG 298
            P    A G P  G   ++  +G       R  V  S      G      P  G  GP   
Sbjct: 1112 PGNPGAPGSP--GPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPI-GPPGPRGN 1168

Query: 299  RATKTLESRP 308
            R  +  E  P
Sbjct: 1169 RGERGSEGSP 1178



 Score = 37.7 bits (86), Expect = 0.045
 Identities = 45/186 (24%), Positives = 59/186 (31%), Gaps = 36/186 (19%)

Query: 122 DAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDP 181
           + G  G  G  GAP +       G      ++ +GG P + G               + P
Sbjct: 802 ETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPP-----------GGSGP 850

Query: 182 LSEPDPPA--RDAASPHQDGAPG-------PGPRGGRGQEWRPAPGPAPGQGAEASAQGR 232
              P P     +  SP   GA G       PGP G  G    P P  +PG+       G 
Sbjct: 851 AGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGN 910

Query: 233 AEEEGLPAKAHADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPL--VQEAPAD 290
               G P  +   G+  AG    +   G    P A             GPL       A 
Sbjct: 911 TGAPGSPGVSGPKGD--AGQPGEKGSPGAQGPPGA------------PGPLGIAGITGAR 956

Query: 291 GMKGPP 296
           G+ GPP
Sbjct: 957 GLAGPP 962



 Score = 37.0 bits (84), Expect = 0.077
 Identities = 37/132 (28%), Positives = 49/132 (37%), Gaps = 20/132 (15%)

Query: 187 PPARDAASPHQDGAPGP----------GPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEE 236
           PP ++  +  Q G PGP          GP G +G +  P  G  PG+  +    G   + 
Sbjct: 607 PPGKNGETGPQ-GPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPKGDA 665

Query: 237 GLPAKAHADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEAPADGMKGPP 296
           G P      G+  A   R   G+       A A  LR    P  GP   +  A G  GPP
Sbjct: 666 GAPGAPGGKGDAGAPGERGPPGL-------AGAPGLRGGAGP-PGPEGGKGAA-GPPGPP 716

Query: 297 SGRATKTLESRP 308
               T  L+  P
Sbjct: 717 GAAGTPGLQGMP 728



 Score = 36.6 bits (83), Expect = 0.10
 Identities = 39/136 (28%), Positives = 46/136 (33%), Gaps = 11/136 (8%)

Query: 124  GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRG-AAEETRDSDLSELSDTDPL 182
            GA G +G  G   E     A G         + G P   G A ++             P+
Sbjct: 1083 GAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPV 1142

Query: 183  SEPDPPARDAASPHQDGAPGPGPRGGRGQ---EWRPA----PGPAPGQGAEASAQGRAEE 235
                PP +D  S H      PGPRG RG+   E  P     PGP    GA     G    
Sbjct: 1143 GPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGAPGPCCGGV-- 1200

Query: 236  EGLPAKAHADGEPKAG 251
             G  A A   GE   G
Sbjct: 1201 -GAAAIAGIGGEKAGG 1215



 Score = 35.8 bits (81), Expect = 0.17
 Identities = 40/136 (29%), Positives = 47/136 (34%), Gaps = 20/136 (14%)

Query: 122  DAGAGGRRGGAGAPREWNVAYALGSA--TGDDDEDDGGGPRLRGAAEETRDSDLSELSDT 179
            D G  G  G  GAP        +G A  +GD  E    GP        +R +        
Sbjct: 1033 DRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGA-------- 1084

Query: 180  DPLSEPDPPARDAASPHQDGAPG-PGPRGGRGQEWRP-APGPAPGQGA-----EASAQGR 232
                 P  P  D     + GA G  G RG  G    P +PGPA  QGA      A  +G 
Sbjct: 1085 ---PGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGP 1141

Query: 233  AEEEGLPAKAHADGEP 248
                G P K    G P
Sbjct: 1142 VGPSGPPGKDGTSGHP 1157



 Score = 35.4 bits (80), Expect = 0.22
 Identities = 37/132 (28%), Positives = 46/132 (34%), Gaps = 9/132 (6%)

Query: 123 AGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPL 182
           AG  G  G AG P    V    GS  G       G   L G      +      S +   
Sbjct: 842 AGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGK 901

Query: 183 SEPDPPARDAASPHQDGAPGP-------GPRGGRGQEWRP-APGPAPGQGAEASAQGRAE 234
             P  PA +  +P   G  GP       G +G  G +  P APGP  G      A+G A 
Sbjct: 902 DGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPL-GIAGITGARGLAG 960

Query: 235 EEGLPAKAHADG 246
             G+P    + G
Sbjct: 961 PPGMPGPRGSPG 972



 Score = 35.0 bits (79), Expect = 0.29
 Identities = 57/221 (25%), Positives = 74/221 (33%), Gaps = 41/221 (18%)

Query: 124  GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLS 183
            G  G RG  G P       A G         + G P   G+    +D       +T    
Sbjct: 858  GVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPG--KDGPPGPAGNTGAPG 915

Query: 184  EP--DPPARDAASPHQDGAPG-------PGP---------RGGRGQEWRPAPGPAPG-QG 224
             P    P  DA  P + G+PG       PGP         RG  G    P P  +PG QG
Sbjct: 916  SPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQG 975

Query: 225  AEASA-----------QGRAEEEGLPAKAHADGEPKAGVRRRRKGV-GRHWVPEARASVL 272
             +  +           +G    +GLP  A   GEP         G+ GR   P  +    
Sbjct: 976  VKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGD-- 1033

Query: 273  RSIQDPWQGPLVQEAPA-DGMKGP--PSGRATKTLESRPLG 310
               +     P    AP   G  GP  P+G++    ES P G
Sbjct: 1034 ---RGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAG 1071



 Score = 34.7 bits (78), Expect = 0.38
 Identities = 26/72 (36%), Positives = 29/72 (40%), Gaps = 14/72 (19%)

Query: 181 PLSEPDPPARDAASPH--QDGAPG----PGPRGGRGQEWRPAP-------GPAPGQGAEA 227
           P   P PP     S H    G+PG    PG  G  G    P P       GPA G+  E+
Sbjct: 175 PAGPPGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPA-GKDGES 233

Query: 228 SAQGRAEEEGLP 239
              GR  E GLP
Sbjct: 234 GRPGRPGERGLP 245



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 33/121 (27%), Positives = 38/121 (31%), Gaps = 13/121 (10%)

Query: 124 GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEET----RDSDLSELSDT 179
           G  G +G AG       A   G+A     +   GGP +RG          D         
Sbjct: 498 GIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQ 557

Query: 180 DPLSEPDPPARDA--ASPHQDGAPGP-------GPRGGRGQEWRPAPGPAPGQGAEASAQ 230
                P PP        P   G PGP       G  G RG    P P   PG+  E   Q
Sbjct: 558 GESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQ 617

Query: 231 G 231
           G
Sbjct: 618 G 618



 Score = 32.3 bits (72), Expect = 1.9
 Identities = 50/191 (26%), Positives = 63/191 (32%), Gaps = 43/191 (22%)

Query: 119 HQCDAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSD 178
           +Q   G  G+ G +G P         G A  D +    G P  RG               
Sbjct: 199 YQGPPGEPGQAGPSGPPGPPGAIGPSGPAGKDGESGRPGRPGERGL-------------- 244

Query: 179 TDPLSEPDPPARDAASPHQDGAPG-PGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEG 237
                 P PP     +    G PG PG +G RG + R       G+  E  A G   E G
Sbjct: 245 ------PGPPGIKGPA----GIPGFPGMKGHRGFDGRN------GEKGETGAPGLKGENG 288

Query: 238 LPAKAHADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEAPADGMKGPPS 297
           LP +  A G    G R      GR  +P A  +      D  +G       +DG  GPP 
Sbjct: 289 LPGENGAPG--PMGPRGAPGERGRPGLPGAAGA---RGNDGARG-------SDGQPGPPG 336

Query: 298 GRATKTLESRP 308
              T      P
Sbjct: 337 PPGTAGFPGSP 347



 Score = 31.6 bits (70), Expect = 3.2
 Identities = 49/201 (24%), Positives = 65/201 (32%), Gaps = 22/201 (10%)

Query: 122 DAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDP 181
           + G  G  G  GAP +       G A     +   G P + G+             +  P
Sbjct: 352 EVGPAGSPGSNGAPGQRGEPGPQGHAGA---QGPPGPPGINGSP--------GGKGEMGP 400

Query: 182 LSEPDPPARDAAS--PHQDGAPG-PGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGL 238
              P  P    A   P   GA G PG RGG G+   P    A G+      +G A   G+
Sbjct: 401 AGIPGAPGLMGARGPPGPAGANGAPGLRGGAGE---PGKNGAKGEPGPRGERGEAGIPGV 457

Query: 239 PAKAHADGEP----KAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEAPADGMKG 294
           P     DG+     + G        G    P  R     +     +GP   E  A G  G
Sbjct: 458 PGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGP-AGERGAPGPAG 516

Query: 295 PPSGRATKTLESRPLGETLRG 315
           P         +  P G  +RG
Sbjct: 517 PRGAAGEPGRDGVPGGPGMRG 537


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 62/208 (29%), Positives = 74/208 (35%), Gaps = 28/208 (13%)

Query: 124  GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAA----------EETRDSDL 173
            G  G RG AG P     A  +    GD  E    GP   GAA          E+     +
Sbjct: 1202 GEKGERGDAGDPGPPG-APGIPGPKGDIGEKGDSGPS--GAAGPPGKKGPPGEDGAKGSV 1258

Query: 174  SELSDTDPLSEPDPPARDA--ASPHQDGAPG----PGPRGGRGQEWRPAPGPAPGQGAEA 227
                    L  P  P       SP + G PG    PGP G  G+   P P    G     
Sbjct: 1259 GPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGAPGPPGKRGPSGHM 1318

Query: 228  SAQGRAEEEGLPAKAHADGEP-KAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQE 286
              +GR  E+G   +   DG P + G    R   GR   PE     LR I  P   P +  
Sbjct: 1319 GREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVG-PEG----LRGIPGPVGEPGLLG 1373

Query: 287  APAD-GMKGP--PSGRATKTLESRPLGE 311
            AP   G  GP  PSG      ++ P GE
Sbjct: 1374 APGQMGPPGPLGPSGLPGLKGDTGPKGE 1401



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 28/81 (34%), Positives = 37/81 (45%), Gaps = 2/81 (2%)

Query: 167  ETRDSDLSELSDTDPLSEPDPPARDAASPHQDGAPG-PGPRGGRGQEWRPAPGPAPGQGA 225
            E R+    EL    PL + + PA     P   G PG PGP G +G +  P P  A G   
Sbjct: 952  EGREGAKGELGPPGPLGK-EGPAGLRGFPGPKGGPGDPGPTGLKGDKGPPGPVGANGSPG 1010

Query: 226  EASAQGRAEEEGLPAKAHADG 246
            E    G A   GLP ++ ++G
Sbjct: 1011 ERGPLGPAGGIGLPGQSGSEG 1031



 Score = 38.9 bits (89), Expect = 0.020
 Identities = 46/158 (29%), Positives = 53/158 (33%), Gaps = 36/158 (22%)

Query: 115 LKRPHQCDAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLS 174
           L+ PH    G  GR G  G P         G      D    G P L G        +  
Sbjct: 516 LQGPH----GPPGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPG--------EKG 563

Query: 175 ELSDTDPLSEPDPPARD----AASP----HQDGAPGP----GPRGGRGQEWRP------- 215
           +  D   + +P PP  D    A  P     Q G PGP    GPRG  G   RP       
Sbjct: 564 QRGDFGHVGQPGPPGEDGERGAEGPPGPTGQAGEPGPRGLLGPRGSPGPTGRPGVTGIDG 623

Query: 216 APGP-----APGQGAEASAQGRAEEEGLPAKAHADGEP 248
           APG       PG+      QG    +GLP      G P
Sbjct: 624 APGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQGLIGTP 661



 Score = 37.4 bits (85), Expect = 0.059
 Identities = 42/137 (30%), Positives = 50/137 (36%), Gaps = 18/137 (13%)

Query: 197 QDGAPG-PGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPAKAHADGEPKAGVRRR 255
           Q GA G PGP+G  GQ+  P      G        G    +G P     DG P    +R 
Sbjct: 843 QPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFPGPKGPPGHQGKDGRPGHPGQRG 902

Query: 256 RKGVGRHWVPEARASVLRSIQDPWQ-GPLVQEAPADGMKGPPSGRATKTLESR------- 307
             G      P   A VL       + GPL +  P  G  GPP  +    LE R       
Sbjct: 903 ELGFQGQTGPPGPAGVLGPQGKTGEVGPLGERGP-PGPPGPPGEQGLPGLEGREGAKGEL 961

Query: 308 ----PLGET----LRGF 316
               PLG+     LRGF
Sbjct: 962 GPPGPLGKEGPAGLRGF 978



 Score = 35.8 bits (81), Expect = 0.17
 Identities = 37/135 (27%), Positives = 49/135 (36%), Gaps = 10/135 (7%)

Query: 124  GAGGRRGGAGAPREWNV---AYALGSATGDDDEDDGGGPRLRGA-AEETRDSDLSELSDT 179
            G+ G +G AG P +  +   A   G    D  +   G P L G   ++     +  +   
Sbjct: 1088 GSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPP 1147

Query: 180  DPLSEPDPPAR-----DAASPHQDGAPGP-GPRGGRGQEWRPAPGPAPGQGAEASAQGRA 233
                 P PP       D  S    GAPGP GP+G  G E  P      GQ      +G  
Sbjct: 1148 GLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQPGAVGEKGER 1207

Query: 234  EEEGLPAKAHADGEP 248
             + G P    A G P
Sbjct: 1208 GDAGDPGPPGAPGIP 1222



 Score = 35.0 bits (79), Expect = 0.29
 Identities = 36/115 (31%), Positives = 49/115 (42%), Gaps = 14/115 (12%)

Query: 197 QDGAPG-PGPRGGRGQEWRP-APGPAPGQGAEA--SAQGRAEEEGLPAKAHADGEPKAGV 252
           +DG PG  G  G +G + +P APGP    G E      G+A EEG P  A   G  K GV
Sbjct: 732 EDGFPGFKGDVGLKGDQGKPGAPGPRGEDGPEGPKGQAGQAGEEGPPGSAGEKG--KLGV 789

Query: 253 RRRRKGVGRHWVPEARASV-----LRSIQDPWQGPLVQEAPADGMKGPPSGRATK 302
                  GR   P  + S+     L  I +  +     +   +G +GPP  R  +
Sbjct: 790 PGLPGYPGR---PGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPGSRGER 841



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 47/178 (26%), Positives = 60/178 (33%), Gaps = 35/178 (19%)

Query: 122 DAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDP 181
           D G  G +G  GAP             G   ED   GP+ + A +   +       +   
Sbjct: 741 DVGLKGDQGKPGAP-------------GPRGEDGPEGPKGQ-AGQAGEEGPPGSAGEKGK 786

Query: 182 LSEPDPPARDAASPHQDGAPG-PGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPA 240
           L  P  P          G PG PGP+G  G      P    G+  +    G   E G P 
Sbjct: 787 LGVPGLP----------GYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQPGLEGERGPPG 836

Query: 241 KAHADGEPKAGVRRRRKG-VGRHWVPEARASV-LRSIQDPWQGPLVQEAPADGMKGPP 296
                G+P A  +   KG VG+   P       L  +Q P   P        G KGPP
Sbjct: 837 SRGERGQPGATGQPGPKGDVGQDGAPGIPGEKGLPGLQGPPGFP--------GPKGPP 886



 Score = 32.0 bits (71), Expect = 2.5
 Identities = 30/99 (30%), Positives = 40/99 (40%), Gaps = 13/99 (13%)

Query: 163  GAAEETRDSDLSELSDTD-PLSEPDPPARDAASPHQDGAPG-PGPRGGRGQEWRPAPGPA 220
            G A E  D  L  +     P  +P PP    +  H  G PG  GP G +G +  P    +
Sbjct: 1415 GEAGEKGDQGLPGVQGPPGPKGDPGPPGPIGSLGH-PGPPGVAGPLGQKGSKGSPG---S 1470

Query: 221  PGQGAEASAQGRAEEEGLPAKAHADGEPKAGVRRRRKGV 259
             G   +    G     G PA+ H       G+RRRR+ V
Sbjct: 1471 MGPRGDTGPAGPPGPPGAPAELH-------GLRRRRRFV 1502



 Score = 30.4 bits (67), Expect = 7.2
 Identities = 34/131 (25%), Positives = 42/131 (32%), Gaps = 11/131 (8%)

Query: 122  DAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDP 181
            + G  G  GG G P +      +G A       + G P   G     +D     L    P
Sbjct: 1011 ERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGERGPPGPTG-----KDGIPGPLGPLGP 1065

Query: 182  LSEPDPPAR-----DAASPHQDGAPGP-GPRGGRGQEWRPAPGPAPGQGAEASAQGRAEE 235
                 P        D  +P   G+ G  G  G  GQ     P   PG      AQGR   
Sbjct: 1066 PGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGP 1125

Query: 236  EGLPAKAHADG 246
             GL  +   DG
Sbjct: 1126 PGLFGQKGDDG 1136


>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
          Length = 1497

 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 78/289 (26%), Positives = 96/289 (33%), Gaps = 46/289 (15%)

Query: 124 GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGG------PRLRGAAEETRDSDLSELS 177
           G  G RG  GA  E     A+G A  D  +   G       P +RG    + D     L+
Sbjct: 722 GEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGKPGLT 781

Query: 178 DTD-PLSEPDPPARDAASPHQDGAPG-------------PGPRGGRGQEWRPAPGPAPGQ 223
               P   P  P R      + GAPG             PGP G  G    P P  APG 
Sbjct: 782 GPQGPQGLPGTPGRPGIKG-EPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPPGAPGP 840

Query: 224 GAEASAQGRAEE---EGLPAKAHADGEPKAGV-----RRRRKGVGRHWVPEARASVLRSI 275
              A   G  E    +G P      G P   +      R   G G    P    S L + 
Sbjct: 841 AGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGSFLSNS 900

Query: 276 QDPWQGPLVQEAP--ADGMKGPPSGRATKTLESRPLGETLRGFCTSEDSDINITSGEEDH 333
           +    GP     P    G +GPP  R  +  +  P      GF TS  S   +       
Sbjct: 901 ETFLSGPPGPPGPPGPKGDQGPPGPRGHQGEQGLP------GFSTSGSSSFGLNLQGPPG 954

Query: 334 KEQPFPGVCNPK-EKNSGRVPRALQDSRAAPAEG---LCCYICGAPLSP 378
                PG   PK +K    VP AL    + P+EG      Y+ G P  P
Sbjct: 955 P----PGPQGPKGDKGDPGVPGAL-GIPSGPSEGGSSSTMYVSGPPGPP 998



 Score = 32.3 bits (72), Expect = 1.9
 Identities = 55/228 (24%), Positives = 72/228 (31%), Gaps = 46/228 (20%)

Query: 122 DAGAGGRRGGAGAPREWNVAYALG-----------SATGDDDEDDGGGPRLR----GAAE 166
           D G+ G +G  G P    +   LG            + GD   +   G R R    G   
Sbjct: 574 DMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPMGQRGREGPMGPRG 633

Query: 167 ETRDSDLSELSDTDPLSEPDP-----------PARDAASPHQDGAPGP------------ 203
           E       E  +     EP P           P   + SP   G PGP            
Sbjct: 634 EAGPPGSGEKGERGAAGEPGPHGPPGVPGSVGPKGSSGSPGPQGPPGPVGLQGLRGEVGL 693

Query: 204 -GPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPAKAHADGEPKAGVRRRRKGVGRH 262
            G +G +G      PGP   QG E   +G   E G+     A GEP A       G   H
Sbjct: 694 PGVKGDKGP--MGPPGPKGDQG-EKGPRGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGH 750

Query: 263 WVPEARASV--LRSIQDPWQGPLVQEAPADGMKGPPSGRATKTLESRP 308
             P     +  +  I+ P  GP   +    G+ GP   +       RP
Sbjct: 751 QGPRGEQGLTGMPGIRGP-PGP-SGDPGKPGLTGPQGPQGLPGTPGRP 796


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 59/209 (28%), Positives = 71/209 (33%), Gaps = 24/209 (11%)

Query: 122 DAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDP 181
           DAGA G  G  GAP    +    G+A     + D G    +GA        +  L  T P
Sbjct: 711 DAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGL--TGP 768

Query: 182 LSEPDPPARDAASPHQDGAPGP-------GPRGGRGQEWRPAPGPAPGQGAEASAQGRAE 234
           +  P P    A +P   G  GP       G RG  G    P P    G      A G+  
Sbjct: 769 IGPPGP----AGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPG 824

Query: 235 EEGLPAKAHADGEP-------KAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEA 287
            +G P  A A G+         AG       VG      AR S        + G   +  
Sbjct: 825 AKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVG 884

Query: 288 P--ADGMKGPPS--GRATKTLESRPLGET 312
           P    G  GPP   G A K     P GET
Sbjct: 885 PPGPSGNAGPPGPPGPAGKEGGKGPRGET 913



 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 38/128 (29%), Positives = 45/128 (35%), Gaps = 4/128 (3%)

Query: 122 DAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDP 181
           DAG  G +G  G+P E      +G      +    G P   GA     D          P
Sbjct: 279 DAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGA--RGNDGATGAAGPPGP 336

Query: 182 LSEPDPPARDAASPHQDGAPGPGPRGGRG-QEWRPAPGPAPGQGAEASAQGRAEEEGLPA 240
                PP    A   +  A   GPRG  G Q  R  PGP PG    A   G    +G P 
Sbjct: 337 TGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGP-PGPAGAAGPAGNPGADGQPG 395

Query: 241 KAHADGEP 248
              A+G P
Sbjct: 396 AKGANGAP 403



 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 72/275 (26%), Positives = 92/275 (33%), Gaps = 34/275 (12%)

Query: 123 AGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPL 182
           AG  G+RG  G P    +    G   G       G   + G        +        P 
Sbjct: 463 AGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPA--GERGSPGPAGPK 520

Query: 183 SEPDPPAR--DAASPH------QDGAPGP----GPRGGRGQEWRPAPGPAPGQGAEASAQ 230
             P    R  +A  P         G+PGP    GP G  GQ+ RP P   PG      A+
Sbjct: 521 GSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPG------AR 574

Query: 231 GRAEEEGLPAKAHADGEP-KAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEAPA 289
           G+A   G P    A GEP KAG R      G    P A     +  +   QGP     PA
Sbjct: 575 GQAGVMGFPGPKGAAGEPGKAGER------GVPGPPGAVGPAGKDGEAGAQGPPGPAGPA 628

Query: 290 D--GMKGPPSGRATKTL--ESRPLGETLRGFCTSEDSDINITSGEEDHKEQPFPGVCNPK 345
              G +GP      + L   + P GE  +        D+          E+ FPG    +
Sbjct: 629 GERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQ 688

Query: 346 EKNSGRVPRALQDSRAAPAEGLCCYICGAPLSPAS 380
                  PR    +  AP         GAP +P S
Sbjct: 689 GPPGPAGPRG---ANGAPGNDGAKGDAGAPGAPGS 720



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 56/198 (28%), Positives = 72/198 (36%), Gaps = 14/198 (7%)

Query: 124  GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLS 183
            GA G  G AGA  +       G A       + G P  +GA         +         
Sbjct: 824  GAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRV 883

Query: 184  EPDPPARDAASPHQDGAPGP-GPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLP--- 239
             P  P+ +A  P   G PGP G  GG+G      P   PG+       G A E+G P   
Sbjct: 884  GPPGPSGNAGPP---GPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGAD 940

Query: 240  AKAHADGEP-KAGVRRRRKGVGRHWVPEARAS-VLRSIQDPWQGPLVQ-EAPADGMKGPP 296
              A A G P   G+  +R  VG   +P  R       +  P   P  Q  + A G +GPP
Sbjct: 941  GPAGAPGTPGPQGIAGQRGVVG---LPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPP 997

Query: 297  SGRATKTLESRPLGETLR 314
                   L   P GE+ R
Sbjct: 998  GPMGPPGLAGPP-GESGR 1014



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 47/163 (28%), Positives = 56/163 (34%), Gaps = 23/163 (14%)

Query: 104 ARTPVDKRMYWLKRPHQCDAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRG 163
           + +P D+    ++ P + D G  G RG AG P    +    G           G P L G
Sbjct: 99  SESPTDQETTGVEGP-KGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGG 157

Query: 164 AAEETRDSDLSELSDTDPLSEPDP--PARDAASPHQDGAPGP----------------GP 205
                      E S T  +S P P  P+     P   GAPGP                GP
Sbjct: 158 NFAPQLSYGYDEKS-TGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGP 216

Query: 206 RGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPAKAHADGEP 248
            G RG    P P    G   EA   GR  E G P    A G P
Sbjct: 217 MGPRGP---PGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLP 256



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 43/151 (28%), Positives = 51/151 (33%), Gaps = 15/151 (9%)

Query: 122 DAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDP 181
           + G  G RG  G P       A G+   D  + D G P   G+        +        
Sbjct: 678 ERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAG 737

Query: 182 LSEPDPPARDAASPHQDGAPG-------------PGPRGGRGQEWRPAP-GPAPGQGAEA 227
           L  P     DA     DG+PG             PGP G  G +    P GPA   GA  
Sbjct: 738 LPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGAR- 796

Query: 228 SAQGRAEEEGLPAKAHADGEPKAGVRRRRKG 258
            A G   E G P  A   G P A  +   KG
Sbjct: 797 GAPGDRGEPGPPGPAGFAGPPGADGQPGAKG 827



 Score = 38.1 bits (87), Expect = 0.035
 Identities = 40/143 (27%), Positives = 48/143 (33%), Gaps = 15/143 (10%)

Query: 122  DAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDT-- 179
            + G  GR G  G P     A   GS   D      G P  +G A +     L        
Sbjct: 912  ETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERG 971

Query: 180  -----DPLSEPDPPARDAASPHQDGAPGP-------GPRGGRGQEWRPAPGPAPGQGAEA 227
                  P  EP       AS  + G PGP       GP G  G+E  P    +PG+    
Sbjct: 972  FPGLPGPSGEPGKQGPSGASGER-GPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSP 1030

Query: 228  SAQGRAEEEGLPAKAHADGEPKA 250
             A+G   E G      A G P A
Sbjct: 1031 GAKGDRGETGPAGPPGAPGAPGA 1053



 Score = 37.4 bits (85), Expect = 0.059
 Identities = 35/127 (27%), Positives = 45/127 (35%), Gaps = 13/127 (10%)

Query: 124  GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLS----ELSDT 179
            GA G  G  G P    +A   G         + G P L G + E      S    E    
Sbjct: 938  GADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPP 997

Query: 180  DPLSEPD---PPARDA--ASPHQDGAPG----PGPRGGRGQEWRPAPGPAPGQGAEASAQ 230
             P+  P    PP       +P  +G+PG    PG +G RG+     P  APG        
Sbjct: 998  GPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPV 1057

Query: 231  GRAEEEG 237
            G A + G
Sbjct: 1058 GPAGKSG 1064



 Score = 37.0 bits (84), Expect = 0.077
 Identities = 36/129 (27%), Positives = 46/129 (35%), Gaps = 14/129 (10%)

Query: 122  DAGAGGRRGGAGAPREWNVAYALGSA--TGDDDEDDGGGPRLRGAAEETRDSDLSELSDT 179
            D G  G  G  GAP        +G A  +GD  E    GP             +  +   
Sbjct: 1035 DRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPA----------GPVGPVGAR 1084

Query: 180  DPLSEPDPPARDAASPHQDGAPG-PGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGL 238
             P   P  P  D     + G  G  G RG  G +  P P  +PG+   + A G A   G 
Sbjct: 1085 GPAG-PQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGP 1143

Query: 239  PAKAHADGE 247
            P  A A G+
Sbjct: 1144 PGSAGAPGK 1152



 Score = 35.0 bits (79), Expect = 0.29
 Identities = 32/101 (31%), Positives = 38/101 (37%), Gaps = 3/101 (2%)

Query: 198 DGAPGP-GPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPAKAHADGEPKA-GVRRR 255
           DGA G  GP G +G+   P    APGQ       G     G P  A A G   A G    
Sbjct: 274 DGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGP 333

Query: 256 RKGVGRHWVPEARASVLRSIQDPWQGPLVQEAPADGMKGPP 296
               G    P    +V    +   QGP   E P  G++G P
Sbjct: 334 PGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGP-QGVRGEP 373



 Score = 35.0 bits (79), Expect = 0.29
 Identities = 34/126 (26%), Positives = 43/126 (34%), Gaps = 4/126 (3%)

Query: 124 GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLS 183
           G+ G +G  G P     A A G A G+   D  G P  +GA      +           S
Sbjct: 362 GSEGPQGVRGEPGPPGPAGAAGPA-GNPGAD--GQPGAKGANGAPGIAGAPGFPGARGPS 418

Query: 184 EPDPPARDAASPHQDGAPG-PGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPAKA 242
            P  P          G PG PG +G  G +  P P    G    A  +G+    G P   
Sbjct: 419 GPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPT 478

Query: 243 HADGEP 248
              G P
Sbjct: 479 GLPGPP 484



 Score = 34.3 bits (77), Expect = 0.50
 Identities = 52/197 (26%), Positives = 72/197 (36%), Gaps = 15/197 (7%)

Query: 123 AGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPL 182
           AG  G  G AG P       A G A         G   +RG       +  +  +  +P 
Sbjct: 331 AGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAG-NPG 389

Query: 183 SEPDPPARDA-ASPHQDGAPG----PGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEG 237
           ++  P A+ A  +P   GAPG     GP G +G    P P    G+     ++G    +G
Sbjct: 390 ADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKG 449

Query: 238 LPAKAHADGEP-KAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEAP-ADGMKGP 295
            P      G P  AG   +R   G     E   + L        GP  +  P ADG+ GP
Sbjct: 450 EPGPVGVQGPPGPAGEEGKRGARG-----EPGPTGLPGPPGERGGPGSRGFPGADGVAGP 504

Query: 296 --PSGRATKTLESRPLG 310
             P+G       + P G
Sbjct: 505 KGPAGERGSPGPAGPKG 521



 Score = 33.9 bits (76), Expect = 0.65
 Identities = 40/142 (28%), Positives = 44/142 (30%), Gaps = 30/142 (21%)

Query: 124 GAGGRRGGAGAPREWNVAYALG--SATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDP 181
           G  G  G AG P     A   G   A G   E    GPR     +  R            
Sbjct: 323 GNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVR------------ 370

Query: 182 LSEPDPPA-----RDAASPHQDGAPG-------PGPRGGRGQEWRPAPGPAPGQGAEASA 229
             EP PP        A +P  DG PG       PG  G  G      P    G G     
Sbjct: 371 -GEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGP 429

Query: 230 QGRAEEEGLPAK---AHADGEP 248
           +G + E G P       A GEP
Sbjct: 430 KGNSGEPGAPGSKGDTGAKGEP 451


>gi|115527070 alpha 2 type VI collagen isoform 2C2a' precursor [Homo
           sapiens]
          Length = 828

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 38/132 (28%), Positives = 49/132 (37%), Gaps = 8/132 (6%)

Query: 124 GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGA----AEETRDSDLSELSDT 179
           G+ G +G  G P         G       + D G P  RG      E  +     +  D 
Sbjct: 436 GSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDA 495

Query: 180 DPLSEPDPPARDAASPHQDGAPGPGPRGGRGQEWRPAP-GPAPGQG--AEASAQGRAEEE 236
            P  +   P      P + G   PGPRG  G++  P P GP  G+G        GR  E+
Sbjct: 496 GPRGDSGQPG-PKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEK 554

Query: 237 GLPAKAHADGEP 248
           G PA     GEP
Sbjct: 555 GEPADPGPPGEP 566



 Score = 34.3 bits (77), Expect = 0.50
 Identities = 37/136 (27%), Positives = 47/136 (34%), Gaps = 30/136 (22%)

Query: 122 DAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDP 181
           + G  G +G  G P       ALG         D G    RG           +     P
Sbjct: 458 EVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRG-----------DSGQPGP 506

Query: 182 LSEPDPPARD----AASPHQDGAPGP-GPRGGRG------------QEWRPA-PGPAPGQ 223
             +P  P         +P + G PGP GP GGRG            ++  PA PGP PG+
Sbjct: 507 KGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGP-PGE 565

Query: 224 GAEASAQGRAEEEGLP 239
                 +G    EG P
Sbjct: 566 PGPRGPRGVPGPEGEP 581



 Score = 33.9 bits (76), Expect = 0.65
 Identities = 31/102 (30%), Positives = 36/102 (35%), Gaps = 14/102 (13%)

Query: 122 DAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDP 181
           D+G  G +G  G P      ++     G   E    GPR      E    D     +   
Sbjct: 500 DSGQPGPKGDPGRP-----GFSYPGPRGAPGEKGEPGPR----GPEGGRGDFGLKGEPGR 550

Query: 182 LSEPDPPARDAASPHQDGAPGP-GPRGGRGQEWRPAPGPAPG 222
             E   PA     P   G PGP GPRG  G E  P P   PG
Sbjct: 551 KGEKGEPA----DPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 49/205 (23%), Positives = 68/205 (33%), Gaps = 33/205 (16%)

Query: 116 KRPHQCDAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSE 175
           +R  Q   G  GR G  G P E     A GS     +    G P ++GA           
Sbjct: 365 ERGDQGGKGDPGRPGRRGPPGEIG---AKGSKGYQGNSGAPGSPGVKGAK---------- 411

Query: 176 LSDTDPLSEPDPPARDAASPHQDGAPG----PGPRGGRGQEWRPAPGPAPGQGAEASAQG 231
                    P P       P + G PG    PG  G +G++  P P    G   E   +G
Sbjct: 412 -------GGPGPRG-PKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKG 463

Query: 232 RAEEEGLPAKAHADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDP----WQGPLVQEA 287
              + GLP      G      ++  +G      P   +       DP    +  P  + A
Sbjct: 464 AKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGA 523

Query: 288 PAD----GMKGPPSGRATKTLESRP 308
           P +    G +GP  GR    L+  P
Sbjct: 524 PGEKGEPGPRGPEGGRGDFGLKGEP 548



 Score = 32.3 bits (72), Expect = 1.9
 Identities = 42/153 (27%), Positives = 52/153 (33%), Gaps = 10/153 (6%)

Query: 124 GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLS 183
           G  G  G  G P    V    G       +   G P L G  +   D    +L    P  
Sbjct: 286 GDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAG--KNGTDGQKGKLGRIGPPG 343

Query: 184 EPDPPARDAASPHQDGAPGPGPR---GGRGQEWRPAPGPAPGQ-GAEASA--QGRAEEEG 237
               P       +   A  PG R   GG+G   RP     PG+ GA+ S   QG +   G
Sbjct: 344 CKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPG 403

Query: 238 LPAKAHADGEPKAGVRRRRKGVGRHWVPEARAS 270
            P    A G P  G R  +   GR   P  + S
Sbjct: 404 SPGVKGAKGGP--GPRGPKGEPGRRGDPGTKGS 434


>gi|115527066 alpha 2 type VI collagen isoform 2C2a precursor [Homo
           sapiens]
          Length = 918

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 38/132 (28%), Positives = 49/132 (37%), Gaps = 8/132 (6%)

Query: 124 GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGA----AEETRDSDLSELSDT 179
           G+ G +G  G P         G       + D G P  RG      E  +     +  D 
Sbjct: 436 GSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDA 495

Query: 180 DPLSEPDPPARDAASPHQDGAPGPGPRGGRGQEWRPAP-GPAPGQG--AEASAQGRAEEE 236
            P  +   P      P + G   PGPRG  G++  P P GP  G+G        GR  E+
Sbjct: 496 GPRGDSGQPG-PKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEK 554

Query: 237 GLPAKAHADGEP 248
           G PA     GEP
Sbjct: 555 GEPADPGPPGEP 566



 Score = 34.3 bits (77), Expect = 0.50
 Identities = 37/136 (27%), Positives = 47/136 (34%), Gaps = 30/136 (22%)

Query: 122 DAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDP 181
           + G  G +G  G P       ALG         D G    RG           +     P
Sbjct: 458 EVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRG-----------DSGQPGP 506

Query: 182 LSEPDPPARD----AASPHQDGAPGP-GPRGGRG------------QEWRPA-PGPAPGQ 223
             +P  P         +P + G PGP GP GGRG            ++  PA PGP PG+
Sbjct: 507 KGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGP-PGE 565

Query: 224 GAEASAQGRAEEEGLP 239
                 +G    EG P
Sbjct: 566 PGPRGPRGVPGPEGEP 581



 Score = 33.9 bits (76), Expect = 0.65
 Identities = 31/102 (30%), Positives = 36/102 (35%), Gaps = 14/102 (13%)

Query: 122 DAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDP 181
           D+G  G +G  G P      ++     G   E    GPR      E    D     +   
Sbjct: 500 DSGQPGPKGDPGRP-----GFSYPGPRGAPGEKGEPGPR----GPEGGRGDFGLKGEPGR 550

Query: 182 LSEPDPPARDAASPHQDGAPGP-GPRGGRGQEWRPAPGPAPG 222
             E   PA     P   G PGP GPRG  G E  P P   PG
Sbjct: 551 KGEKGEPA----DPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 49/205 (23%), Positives = 68/205 (33%), Gaps = 33/205 (16%)

Query: 116 KRPHQCDAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSE 175
           +R  Q   G  GR G  G P E     A GS     +    G P ++GA           
Sbjct: 365 ERGDQGGKGDPGRPGRRGPPGEIG---AKGSKGYQGNSGAPGSPGVKGAK---------- 411

Query: 176 LSDTDPLSEPDPPARDAASPHQDGAPG----PGPRGGRGQEWRPAPGPAPGQGAEASAQG 231
                    P P       P + G PG    PG  G +G++  P P    G   E   +G
Sbjct: 412 -------GGPGPRG-PKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKG 463

Query: 232 RAEEEGLPAKAHADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDP----WQGPLVQEA 287
              + GLP      G      ++  +G      P   +       DP    +  P  + A
Sbjct: 464 AKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGA 523

Query: 288 PAD----GMKGPPSGRATKTLESRP 308
           P +    G +GP  GR    L+  P
Sbjct: 524 PGEKGEPGPRGPEGGRGDFGLKGEP 548



 Score = 32.3 bits (72), Expect = 1.9
 Identities = 42/153 (27%), Positives = 52/153 (33%), Gaps = 10/153 (6%)

Query: 124 GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLS 183
           G  G  G  G P    V    G       +   G P L G  +   D    +L    P  
Sbjct: 286 GDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAG--KNGTDGQKGKLGRIGPPG 343

Query: 184 EPDPPARDAASPHQDGAPGPGPR---GGRGQEWRPAPGPAPGQ-GAEASA--QGRAEEEG 237
               P       +   A  PG R   GG+G   RP     PG+ GA+ S   QG +   G
Sbjct: 344 CKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPG 403

Query: 238 LPAKAHADGEPKAGVRRRRKGVGRHWVPEARAS 270
            P    A G P  G R  +   GR   P  + S
Sbjct: 404 SPGVKGAKGGP--GPRGPKGEPGRRGDPGTKGS 434


>gi|115527062 alpha 2 type VI collagen isoform 2C2 precursor [Homo
           sapiens]
          Length = 1019

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 38/132 (28%), Positives = 49/132 (37%), Gaps = 8/132 (6%)

Query: 124 GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGA----AEETRDSDLSELSDT 179
           G+ G +G  G P         G       + D G P  RG      E  +     +  D 
Sbjct: 436 GSDGPKGEKGDPGPEGPRGLAGEVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDA 495

Query: 180 DPLSEPDPPARDAASPHQDGAPGPGPRGGRGQEWRPAP-GPAPGQG--AEASAQGRAEEE 236
            P  +   P      P + G   PGPRG  G++  P P GP  G+G        GR  E+
Sbjct: 496 GPRGDSGQPG-PKGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEK 554

Query: 237 GLPAKAHADGEP 248
           G PA     GEP
Sbjct: 555 GEPADPGPPGEP 566



 Score = 34.3 bits (77), Expect = 0.50
 Identities = 37/136 (27%), Positives = 47/136 (34%), Gaps = 30/136 (22%)

Query: 122 DAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDP 181
           + G  G +G  G P       ALG         D G    RG           +     P
Sbjct: 458 EVGNKGAKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRG-----------DSGQPGP 506

Query: 182 LSEPDPPARD----AASPHQDGAPGP-GPRGGRG------------QEWRPA-PGPAPGQ 223
             +P  P         +P + G PGP GP GGRG            ++  PA PGP PG+
Sbjct: 507 KGDPGRPGFSYPGPRGAPGEKGEPGPRGPEGGRGDFGLKGEPGRKGEKGEPADPGP-PGE 565

Query: 224 GAEASAQGRAEEEGLP 239
                 +G    EG P
Sbjct: 566 PGPRGPRGVPGPEGEP 581



 Score = 33.9 bits (76), Expect = 0.65
 Identities = 31/102 (30%), Positives = 36/102 (35%), Gaps = 14/102 (13%)

Query: 122 DAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDP 181
           D+G  G +G  G P      ++     G   E    GPR      E    D     +   
Sbjct: 500 DSGQPGPKGDPGRP-----GFSYPGPRGAPGEKGEPGPR----GPEGGRGDFGLKGEPGR 550

Query: 182 LSEPDPPARDAASPHQDGAPGP-GPRGGRGQEWRPAPGPAPG 222
             E   PA     P   G PGP GPRG  G E  P P   PG
Sbjct: 551 KGEKGEPA----DPGPPGEPGPRGPRGVPGPEGEPGPPGDPG 588



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 49/205 (23%), Positives = 68/205 (33%), Gaps = 33/205 (16%)

Query: 116 KRPHQCDAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSE 175
           +R  Q   G  GR G  G P E     A GS     +    G P ++GA           
Sbjct: 365 ERGDQGGKGDPGRPGRRGPPGEIG---AKGSKGYQGNSGAPGSPGVKGAK---------- 411

Query: 176 LSDTDPLSEPDPPARDAASPHQDGAPG----PGPRGGRGQEWRPAPGPAPGQGAEASAQG 231
                    P P       P + G PG    PG  G +G++  P P    G   E   +G
Sbjct: 412 -------GGPGPRG-PKGEPGRRGDPGTKGSPGSDGPKGEKGDPGPEGPRGLAGEVGNKG 463

Query: 232 RAEEEGLPAKAHADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDP----WQGPLVQEA 287
              + GLP      G      ++  +G      P   +       DP    +  P  + A
Sbjct: 464 AKGDRGLPGPRGPQGALGEPGKQGSRGDPGDAGPRGDSGQPGPKGDPGRPGFSYPGPRGA 523

Query: 288 PAD----GMKGPPSGRATKTLESRP 308
           P +    G +GP  GR    L+  P
Sbjct: 524 PGEKGEPGPRGPEGGRGDFGLKGEP 548



 Score = 32.3 bits (72), Expect = 1.9
 Identities = 42/153 (27%), Positives = 52/153 (33%), Gaps = 10/153 (6%)

Query: 124 GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLS 183
           G  G  G  G P    V    G       +   G P L G  +   D    +L    P  
Sbjct: 286 GDPGIEGPIGFPGPKGVPGFKGEKGEFGADGRKGAPGLAG--KNGTDGQKGKLGRIGPPG 343

Query: 184 EPDPPARDAASPHQDGAPGPGPR---GGRGQEWRPAPGPAPGQ-GAEASA--QGRAEEEG 237
               P       +   A  PG R   GG+G   RP     PG+ GA+ S   QG +   G
Sbjct: 344 CKGDPGNRGPDGYPGEAGSPGERGDQGGKGDPGRPGRRGPPGEIGAKGSKGYQGNSGAPG 403

Query: 238 LPAKAHADGEPKAGVRRRRKGVGRHWVPEARAS 270
            P    A G P  G R  +   GR   P  + S
Sbjct: 404 SPGVKGAKGGP--GPRGPKGEPGRRGDPGTKGS 434


>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
           potassium channel 2 [Homo sapiens]
          Length = 889

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 42/147 (28%), Positives = 52/147 (35%), Gaps = 32/147 (21%)

Query: 185 PDPPARDAASPHQDGAPGPGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPAKAHA 244
           P PP     +P Q   P P P         PAP P PG    A  Q     E LP +A  
Sbjct: 20  PGPPPPPPPAPPQQQPPPPPP---------PAPPPGPGP---APPQHPPRAEALPPEAAD 67

Query: 245 DGEPKAGVRRRRKGVGRHWVPEARASVLRSIQ------DPWQGPLVQEAPADGMK----- 293
           +G P+  +R R    GR   P A ++   S        +P   P   E PA G K     
Sbjct: 68  EGGPRGRLRSRDSSCGRPGTPGAASTAKGSPNGECGRGEPQCSPAGPEGPARGPKVSFSC 127

Query: 294 ---------GPPSGRATKTLESRPLGE 311
                    GP       + E+ P GE
Sbjct: 128 RGAASGPAPGPGPAEEAGSEEAGPAGE 154


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 56/205 (27%), Positives = 67/205 (32%), Gaps = 48/205 (23%)

Query: 122  DAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDP 181
            + G  G  G AG P             GDD      GP             +    D  P
Sbjct: 1310 EKGESGPSGAAGPPGP-------KGPPGDDGPKGSPGP-------------VGFPGDPGP 1349

Query: 182  LSEPDPPARDA--------ASPHQDGAPGP----GPRGGRGQEWRPAPGPAPGQGAEASA 229
              EP P  +D           P Q G+PGP    GP G  G+   P P    G+  E  A
Sbjct: 1350 PGEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGA 1409

Query: 230  QGRAEEEGLPAKAHADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEAPA 289
            +G A  EG P K    G   A  +    G             LR I  P     +  +P 
Sbjct: 1410 KGEAGLEGPPGKTGPIGPQGAPGKPGPDG-------------LRGIPGPVGEQGLPGSPG 1456

Query: 290  -DGMKGP--PSGRATKTLESRPLGE 311
             DG  GP  P G      +S P GE
Sbjct: 1457 PDGPPGPMGPPGLPGLKGDSGPKGE 1481



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 54/186 (29%), Positives = 63/186 (33%), Gaps = 18/186 (9%)

Query: 119  HQCDAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSD 178
            H    G  G +G  G P    V    G         + G P   G   E     L+    
Sbjct: 977  HPGQRGETGFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLPGLAGKEG 1036

Query: 179  T--DP----LSEPDPPARDAASPHQDGAPGP-GPRGGRGQEWRPAPGPAPGQGAEASAQG 231
            T  DP    L   D P      P   G PGP G  G +G E  P P    G   E    G
Sbjct: 1037 TKGDPGPAGLPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAG 1096

Query: 232  RAEEEGLPAKAHADGEP-KAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEAPAD 290
             A   G+P +    G P  AG     KG      P+  A      +D  QGP+    PA 
Sbjct: 1097 AAGPIGIPGRPGPQGPPGPAG----EKGAPGEKGPQGPAG-----RDGLQGPVGLPGPA- 1146

Query: 291  GMKGPP 296
            G  GPP
Sbjct: 1147 GPVGPP 1152



 Score = 38.1 bits (87), Expect = 0.035
 Identities = 40/137 (29%), Positives = 48/137 (35%), Gaps = 20/137 (14%)

Query: 123 AGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPL 182
           AG  GRRG AG+    + A  +   TG   + D G   L G   E          D  P 
Sbjct: 603 AGKPGRRGRAGS----DGARGMPGQTGP--KGDRGFDGLAGLPGEK-----GHRGDPGPS 651

Query: 183 SEPDPPARDAASPHQD-----GAPG-PGPRG---GRGQEWRPAPGPAPGQGAEASAQGRA 233
             P PP  D            G PG PGPRG    +G    P P    G   +   +G  
Sbjct: 652 GPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPKGNV 711

Query: 234 EEEGLPAKAHADGEPKA 250
             +G P      G P A
Sbjct: 712 GPQGEPGPPGQQGNPGA 728



 Score = 35.8 bits (81), Expect = 0.17
 Identities = 45/142 (31%), Positives = 49/142 (34%), Gaps = 31/142 (21%)

Query: 123 AGAGGRRGGAGAPREWNVAYALGSATGDDDE--DDGG-GPRLRGAAEETRDSDLSELSDT 179
           AG  G +G  G P             GDD E  DDG  GPR  G   E     L  L   
Sbjct: 636 AGLPGEKGHRGDPGPSGPP----GPPGDDGERGDDGEVGPR--GLPGEPGPRGL--LGPK 687

Query: 180 DPLSEPDPPARDAASPHQDGAPGP-------------GPRGGRGQEWRPAPGPAPGQGAE 226
            P   P PP         DG PGP             G +G  G +  P P  A G   E
Sbjct: 688 GPPGPPGPPGVTG----MDGQPGPKGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGE 743

Query: 227 ASAQGRAEEEGLPAKAHADGEP 248
               G+    GLP    ADG P
Sbjct: 744 KGPLGK---PGLPGMPGADGPP 762



 Score = 35.8 bits (81), Expect = 0.17
 Identities = 44/152 (28%), Positives = 55/152 (36%), Gaps = 25/152 (16%)

Query: 175  ELSDTDPLSEPDPPARDAAS--PHQDGAPGP----GPRGGRGQEWRPA----PGPAPGQG 224
            E  D   +  P PP     S  P  DG  GP    G  G  G++  P     PG  PG+G
Sbjct: 1241 ETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPG-LPGEG 1299

Query: 225  AEASAQGRAEEEGLPAKAHADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLV 284
                 +G   E+G    + A G P        KG      P+     +    DP  GP  
Sbjct: 1300 GPPGPKGERGEKGESGPSGAAGPPGP------KGPPGDDGPKGSPGPVGFPGDP--GPPG 1351

Query: 285  QEAPADGMKGPP-----SGRATKTLESRPLGE 311
            +  PA G  GPP      G   +T    P GE
Sbjct: 1352 EPGPA-GQDGPPGDKGDDGEPGQTGSPGPTGE 1382



 Score = 35.4 bits (80), Expect = 0.22
 Identities = 23/72 (31%), Positives = 29/72 (40%), Gaps = 8/72 (11%)

Query: 181 PLSEPDPPARDAASPHQDGAPGP----GPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEE 236
           P  EP PP +   +P   G PGP    GP G +G   +P     PG        G   +E
Sbjct: 713 PQGEPGPPGQQ-GNPGAQGLPGPQGAIGPPGEKGPLGKPG---LPGMPGADGPPGHPGKE 768

Query: 237 GLPAKAHADGEP 248
           G P +    G P
Sbjct: 769 GPPGEKGGQGPP 780



 Score = 34.7 bits (78), Expect = 0.38
 Identities = 51/200 (25%), Positives = 64/200 (32%), Gaps = 35/200 (17%)

Query: 123  AGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEET-RDSDLSELSDTDP 181
            AG+ G RG AGA     +    G         + G P  +G      RD     +    P
Sbjct: 1086 AGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGP 1145

Query: 182  LSEPDPPARDA-----ASPHQDGA---------PGP-GPRGGRGQEWRPAPGPAPGQGAE 226
                 PP  D        P Q G+         PGP GP+G  GQ   P P  A G+   
Sbjct: 1146 AGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQ---PGPSGADGEPGP 1202

Query: 227  ASAQGRAEEEGLPAKAHADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQE 286
               QG   ++G        G P          VG   +P        +      GP    
Sbjct: 1203 RGQQGLFGQKGDEGPRGFPGPPGP--------VGLQGLPGPPGEKGETGDVGQMGPPGPP 1254

Query: 287  AP--------ADGMKGPPSG 298
             P        ADG +GPP G
Sbjct: 1255 GPRGPSGAPGADGPQGPPGG 1274



 Score = 33.5 bits (75), Expect = 0.85
 Identities = 43/156 (27%), Positives = 50/156 (32%), Gaps = 32/156 (20%)

Query: 124  GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLS 183
            G+ G +G  G P        +G   G    D   GPR        +     +  D  P  
Sbjct: 1168 GSKGDKGEQGPPGPTGPQGPIGQP-GPSGADGEPGPR-------GQQGLFGQKGDEGPRG 1219

Query: 184  EPDPPARDAAS-----PHQDGAPG-------PGPRGGRGQEWRP-APGPA--------PG 222
             P PP           P + G  G       PGP G RG    P A GP         PG
Sbjct: 1220 FPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPG 1279

Query: 223  QGAEASAQGRAEEEGLPAKAHADGEPKAGVRRRRKG 258
               E    G A E GLP +    G P     R  KG
Sbjct: 1280 AVGEKGEPGEAGEPGLPGEG---GPPGPKGERGEKG 1312



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 27/104 (25%), Positives = 42/104 (40%), Gaps = 7/104 (6%)

Query: 124  GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLS 183
            G  G +G  G P    +   +G      ++ D G P  +G++    +  ++    + P+ 
Sbjct: 1474 GDSGPKGEKGHP---GLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGIT--GPSGPIG 1528

Query: 184  EPDPPARDAASPHQDGAPG-PGPRGGRGQEWRPAPGPAPGQGAE 226
             P PP      P   GA G  GP G +G+   P P   PG   E
Sbjct: 1529 PPGPPGL-PGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGE 1571



 Score = 32.7 bits (73), Expect = 1.5
 Identities = 36/138 (26%), Positives = 46/138 (33%), Gaps = 23/138 (16%)

Query: 124  GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLS 183
            G  G+RG  G PR       +    G      G GP      E   +          P  
Sbjct: 907  GPRGQRGPTG-PRGERGPRGITGKPGPKGNSGGDGPA-GPPGERGPNGPQGPTGFPGPKG 964

Query: 184  EPDPPARDAASPH-----------QDGAPGP----GPRGGRGQEWRPAPGPAPGQGAEAS 228
             P PP +D    H           + G PGP    GP+G  G+      GP  G+     
Sbjct: 965  PPGPPGKDGLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGET-----GPM-GERGHPG 1018

Query: 229  AQGRAEEEGLPAKAHADG 246
              G   E+GLP  A  +G
Sbjct: 1019 PPGPPGEQGLPGLAGKEG 1036



 Score = 31.2 bits (69), Expect = 4.2
 Identities = 17/50 (34%), Positives = 24/50 (48%), Gaps = 4/50 (8%)

Query: 199 GAPGP-GPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPAKAHADGE 247
           G PG  GP+G RG +  P P   PG+   A + G     G+P +    G+
Sbjct: 583 GEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDG---ARGMPGQTGPKGD 629



 Score = 31.2 bits (69), Expect = 4.2
 Identities = 38/126 (30%), Positives = 45/126 (35%), Gaps = 17/126 (13%)

Query: 124  GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPR-LRGAAEETRDSDLSELSDTDPL 182
            GA G +GG G P +           G   +    GPR  RG    T        S  D  
Sbjct: 892  GANGEKGGRGTPGK----------PGPRGQRGPTGPRGERGPRGITGKPGPKGNSGGDGP 941

Query: 183  SEPDPPARDAASPH-QDGAPGP-GPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPA 240
            + P P  R    P    G PGP GP G  G++  P     PGQ  E   QG+    G P 
Sbjct: 942  AGP-PGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGH---PGQRGETGFQGKTGPPGPPG 997

Query: 241  KAHADG 246
                 G
Sbjct: 998  VVGPQG 1003



 Score = 30.4 bits (67), Expect = 7.2
 Identities = 23/75 (30%), Positives = 28/75 (37%), Gaps = 11/75 (14%)

Query: 181 PLSEPDPPARDAASPHQDGAPG-------PGPRGGRGQEWRPAPGPAPGQGAEASAQGRA 233
           PL +P  P      P  DG PG       PG +GG+G      P   PG      A G  
Sbjct: 746 PLGKPGLPGM----PGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIR 801

Query: 234 EEEGLPAKAHADGEP 248
             +G   +   DG P
Sbjct: 802 GLKGTKGEKGEDGFP 816



 Score = 30.4 bits (67), Expect = 7.2
 Identities = 38/149 (25%), Positives = 49/149 (32%), Gaps = 16/149 (10%)

Query: 116  KRPHQCDAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPR---LRGAAEETRDSD 172
            KR     AG  GR+G  GA  E  +    G       +   G P    LRG      +  
Sbjct: 1391 KRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPVGEQG 1450

Query: 173  LSELSDTD----PLSEPDPPAR--DAASPHQDGAPG-------PGPRGGRGQEWRPAPGP 219
            L      D    P+  P  P    D+    + G PG       PG +G +G    P P  
Sbjct: 1451 LPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQG 1510

Query: 220  APGQGAEASAQGRAEEEGLPAKAHADGEP 248
            + G   E    G +   G P      G P
Sbjct: 1511 SSGPKGEQGITGPSGPIGPPGPPGLPGPP 1539


>gi|156151396 heterogeneous nuclear ribonucleoprotein R isoform 3
           [Homo sapiens]
          Length = 535

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 51/186 (27%), Positives = 69/186 (37%), Gaps = 27/186 (14%)

Query: 96  EQWAAFERARTPVDKRMYWLKRPHQCDA----GAGGRRGGAGAPREWN---------VAY 142
           E+ AA + +R+   +  Y+   P         G GG RGG G P ++            Y
Sbjct: 320 ERQAARQASRSTAYEDYYYHPPPRMPPPIRGRGRGGGRGGYGYPPDYYGYEDYYDDYYGY 379

Query: 143 ALGSATGDDDE-----DDGGGPRLRGAAEETRDSDLSELSDTDPLSEPDPPARDAASPHQ 197
                 G  ++     DDG   R RG     R +         P     PP R  A   Q
Sbjct: 380 DYHDYRGGYEDPYYGYDDGYAVRGRGGGRGGRGAP------PPPRGRGAPPPRGRAGYSQ 433

Query: 198 DGAPGPGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPAKAHADGEPKAGVRRRRK 257
            GAP   PRG RG    PA     G+G+  S   R    G   K  ADG  +   +RR+ 
Sbjct: 434 RGAPLGPPRGSRGGRGGPAQ-QQRGRGSRGSRGNRGGNVG--GKRKADGYNQPDSKRRQT 490

Query: 258 GVGRHW 263
              ++W
Sbjct: 491 NNQQNW 496


>gi|156151394 heterogeneous nuclear ribonucleoprotein R isoform 1
           [Homo sapiens]
          Length = 636

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 51/186 (27%), Positives = 69/186 (37%), Gaps = 27/186 (14%)

Query: 96  EQWAAFERARTPVDKRMYWLKRPHQCDA----GAGGRRGGAGAPREWN---------VAY 142
           E+ AA + +R+   +  Y+   P         G GG RGG G P ++            Y
Sbjct: 421 ERQAARQASRSTAYEDYYYHPPPRMPPPIRGRGRGGGRGGYGYPPDYYGYEDYYDDYYGY 480

Query: 143 ALGSATGDDDE-----DDGGGPRLRGAAEETRDSDLSELSDTDPLSEPDPPARDAASPHQ 197
                 G  ++     DDG   R RG     R +         P     PP R  A   Q
Sbjct: 481 DYHDYRGGYEDPYYGYDDGYAVRGRGGGRGGRGAP------PPPRGRGAPPPRGRAGYSQ 534

Query: 198 DGAPGPGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPAKAHADGEPKAGVRRRRK 257
            GAP   PRG RG    PA     G+G+  S   R    G   K  ADG  +   +RR+ 
Sbjct: 535 RGAPLGPPRGSRGGRGGPAQ-QQRGRGSRGSRGNRGGNVG--GKRKADGYNQPDSKRRQT 591

Query: 258 GVGRHW 263
              ++W
Sbjct: 592 NNQQNW 597


>gi|156151392 heterogeneous nuclear ribonucleoprotein R isoform 4
           [Homo sapiens]
          Length = 532

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 51/186 (27%), Positives = 69/186 (37%), Gaps = 27/186 (14%)

Query: 96  EQWAAFERARTPVDKRMYWLKRPHQCDA----GAGGRRGGAGAPREWN---------VAY 142
           E+ AA + +R+   +  Y+   P         G GG RGG G P ++            Y
Sbjct: 317 ERQAARQASRSTAYEDYYYHPPPRMPPPIRGRGRGGGRGGYGYPPDYYGYEDYYDDYYGY 376

Query: 143 ALGSATGDDDE-----DDGGGPRLRGAAEETRDSDLSELSDTDPLSEPDPPARDAASPHQ 197
                 G  ++     DDG   R RG     R +         P     PP R  A   Q
Sbjct: 377 DYHDYRGGYEDPYYGYDDGYAVRGRGGGRGGRGAP------PPPRGRGAPPPRGRAGYSQ 430

Query: 198 DGAPGPGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPAKAHADGEPKAGVRRRRK 257
            GAP   PRG RG    PA     G+G+  S   R    G   K  ADG  +   +RR+ 
Sbjct: 431 RGAPLGPPRGSRGGRGGPAQ-QQRGRGSRGSRGNRGGNVG--GKRKADGYNQPDSKRRQT 487

Query: 258 GVGRHW 263
              ++W
Sbjct: 488 NNQQNW 493


>gi|5031755 heterogeneous nuclear ribonucleoprotein R isoform 2
           [Homo sapiens]
          Length = 633

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 51/186 (27%), Positives = 69/186 (37%), Gaps = 27/186 (14%)

Query: 96  EQWAAFERARTPVDKRMYWLKRPHQCDA----GAGGRRGGAGAPREWN---------VAY 142
           E+ AA + +R+   +  Y+   P         G GG RGG G P ++            Y
Sbjct: 418 ERQAARQASRSTAYEDYYYHPPPRMPPPIRGRGRGGGRGGYGYPPDYYGYEDYYDDYYGY 477

Query: 143 ALGSATGDDDE-----DDGGGPRLRGAAEETRDSDLSELSDTDPLSEPDPPARDAASPHQ 197
                 G  ++     DDG   R RG     R +         P     PP R  A   Q
Sbjct: 478 DYHDYRGGYEDPYYGYDDGYAVRGRGGGRGGRGAP------PPPRGRGAPPPRGRAGYSQ 531

Query: 198 DGAPGPGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPAKAHADGEPKAGVRRRRK 257
            GAP   PRG RG    PA     G+G+  S   R    G   K  ADG  +   +RR+ 
Sbjct: 532 RGAPLGPPRGSRGGRGGPAQ-QQRGRGSRGSRGNRGGNVG--GKRKADGYNQPDSKRRQT 588

Query: 258 GVGRHW 263
              ++W
Sbjct: 589 NNQQNW 594


>gi|66932986 filamin-binding LIM protein-1 isoform b [Homo sapiens]
          Length = 374

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 49/183 (26%), Positives = 75/183 (40%), Gaps = 32/183 (17%)

Query: 278 PWQGPLVQEAPADGMKGPPS-----GRATKTLESRPLGETLRGFCTSEDSDINITSGEED 332
           PW+ P   + P  G+ G PS     GRA  T+ + P+ +   G C        +  GE+ 
Sbjct: 42  PWEAPAPMKTPEAGLAGRPSPWTTPGRAAATVPAAPM-QLFNGGCPPPPP---VLDGEDV 97

Query: 333 HKE-------QPFPGVCNPKEKNSGRVPRALQDSRAAPAEGLCCYICGAPLSPASHHQVH 385
             +        P P V  P E+ +   P  +  S  A  E L        LSP       
Sbjct: 98  LPDLDLLPPPPPPPPVLLPSEEEA---PAPMGASLIADLEQL-------HLSPPPPPPQA 147

Query: 386 VQKQEKLAQAPFFPFLWLHSPPPGAQPISEGGSTLVCASCFSSLTQQWQSFELANVPVLQ 445
             +   +   P  P +    PPP A+P+ +G ST +CA C  +++ +    ELA V  ++
Sbjct: 148 PAEGPSVQPGPLRP-MEEELPPPPAEPVEKGASTDICAFCHKTVSPR----ELA-VEAMK 201

Query: 446 RLY 448
           R Y
Sbjct: 202 RQY 204



 Score = 32.3 bits (72), Expect = 1.9
 Identities = 20/70 (28%), Positives = 28/70 (40%), Gaps = 10/70 (14%)

Query: 621 PFFPFLTVYPPAPRARPVDSTGLVATCVLCYHDLLAQWLQHEARSSHHAVSAWSRQYQVE 680
           P  P     PP P A PV+       C  C+  +  + L         AV A  RQY  +
Sbjct: 158 PLRPMEEELPPPP-AEPVEKGASTDICAFCHKTVSPREL---------AVEAMKRQYHAQ 207

Query: 681 TFVCFFCQQE 690
            F C  C+++
Sbjct: 208 CFTCRTCRRQ 217


>gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens]
          Length = 373

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 49/183 (26%), Positives = 75/183 (40%), Gaps = 32/183 (17%)

Query: 278 PWQGPLVQEAPADGMKGPPS-----GRATKTLESRPLGETLRGFCTSEDSDINITSGEED 332
           PW+ P   + P  G+ G PS     GRA  T+ + P+ +   G C        +  GE+ 
Sbjct: 42  PWEAPAPMKTPEAGLAGRPSPWTTPGRAAATVPAAPM-QLFNGGCPPPPP---VLDGEDV 97

Query: 333 HKE-------QPFPGVCNPKEKNSGRVPRALQDSRAAPAEGLCCYICGAPLSPASHHQVH 385
             +        P P V  P E+ +   P  +  S  A  E L        LSP       
Sbjct: 98  LPDLDLLPPPPPPPPVLLPSEEEA---PAPMGASLIADLEQL-------HLSPPPPPPQA 147

Query: 386 VQKQEKLAQAPFFPFLWLHSPPPGAQPISEGGSTLVCASCFSSLTQQWQSFELANVPVLQ 445
             +   +   P  P +    PPP A+P+ +G ST +CA C  +++ +    ELA V  ++
Sbjct: 148 PAEGPSVQPGPLRP-MEEELPPPPAEPVEKGASTDICAFCHKTVSPR----ELA-VEAMK 201

Query: 446 RLY 448
           R Y
Sbjct: 202 RQY 204



 Score = 32.3 bits (72), Expect = 1.9
 Identities = 20/70 (28%), Positives = 28/70 (40%), Gaps = 10/70 (14%)

Query: 621 PFFPFLTVYPPAPRARPVDSTGLVATCVLCYHDLLAQWLQHEARSSHHAVSAWSRQYQVE 680
           P  P     PP P A PV+       C  C+  +  + L         AV A  RQY  +
Sbjct: 158 PLRPMEEELPPPP-AEPVEKGASTDICAFCHKTVSPREL---------AVEAMKRQYHAQ 207

Query: 681 TFVCFFCQQE 690
            F C  C+++
Sbjct: 208 CFTCRTCRRQ 217


>gi|40805823 collagen, type XXII, alpha 1 [Homo sapiens]
          Length = 1626

 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 63/219 (28%), Positives = 85/219 (38%), Gaps = 32/219 (14%)

Query: 102 ERARTPVDKRMYWLKRPH-QCDAGAGGRRGGAGA---PREWNVAYALG--SATGDDDE-- 153
           +R  TP  +++ +LK  +  C AG  G  G AG    P       A+G   A G   E  
Sbjct: 458 QRPPTPGSEQIGFLKTINCSCPAGEKGEMGVAGPMGLPGPKGDIGAIGPVGAPGPKGEKG 517

Query: 154 DDGGGPRLRGAAEETRDSDLSELSDTDPLSEPDPPARDAAS-----PHQDGAPG-PGPRG 207
           D G GP  +G           E  +   L  P PP RD +      P + G PG PG  G
Sbjct: 518 DVGIGPFGQG-----------EKGEKGSLGLPGPPGRDGSKGMRGEPGELGEPGLPGEVG 566

Query: 208 GRGQEWRPA-PGP-----APGQGAEASAQGRAEEEGLPAKAHADGEPKAGVRRRRKGVGR 261
            RG +  P  PGP     APG   E   +G   E+G        G+P    ++ R G   
Sbjct: 567 MRGPQGPPGLPGPPGRVGAPGLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSG 626

Query: 262 HWVPEARASVLRSIQDPW-QGPLVQEAPADGMKGPPSGR 299
              P+     +     P   G +VQ+    G +G P  R
Sbjct: 627 VAGPQGEKGDVGPAGPPGVPGSVVQQEGLKGEQGAPGPR 665



 Score = 43.9 bits (102), Expect = 6e-04
 Identities = 62/252 (24%), Positives = 82/252 (32%), Gaps = 31/252 (12%)

Query: 122  DAGAGGRRGGAGAPREWNVAYALGSATGDDD-EDDGGGPRLRGAAEETRDSDLSELSDTD 180
            + G  G  G  G P   ++        G+   + + G P L G  E        EL    
Sbjct: 838  EKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPG--EPGLQGRPGELGPQG 895

Query: 181  PLSEPDPPARDAA-----SPHQDGAPG----PGPRGGRGQEWRPAPGPAPGQGAEASAQG 231
            P   P    ++ A     +    GAPG    PGP G  G    P     PG+  E   +G
Sbjct: 896  PTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKG 955

Query: 232  RAEEEGLPAKAHADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEAPADG 291
             A EEG P      G+P A       G G+   P  R S          GPL  +A    
Sbjct: 956  AAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGS------PGLPGPLGTKAACGK 1009

Query: 292  MKGPPSGRATKTLESRPLGETLRGFCTSEDSDINITSGEEDHKEQPFPGVCNPKEKNSGR 351
            ++G          E+  LG    G C   D       G    +  P  GV  P   +   
Sbjct: 1010 VRGS---------ENCALG----GQCVKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPP 1056

Query: 352  VPRALQDSRAAP 363
              +    SR  P
Sbjct: 1057 GDKGSPGSRGLP 1068



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 38/136 (27%), Positives = 46/136 (33%), Gaps = 16/136 (11%)

Query: 122 DAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDP 181
           + GA G RG  GAP        +G    D      G P L+G   +  D     +     
Sbjct: 658 EQGAPGPRGHQGAPGPPGARGPIGPEGRD------GPPGLQGLRGKKGDMGPPGIPGLLG 711

Query: 182 LSEPDPPARDAASPHQDGAPG----------PGPRGGRGQEWRPAPGPAPGQGAEASAQG 231
           L  P  P      P   G+PG          PGP G  G   +  P   PG        G
Sbjct: 712 LQGPPGPPGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPPGKDGPNGPPGPPGTKGEPG 771

Query: 232 RAEEEGLPAKAHADGE 247
              E+GLP K    GE
Sbjct: 772 ERGEDGLPGKPGLRGE 787



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 38/123 (30%), Positives = 48/123 (39%), Gaps = 24/123 (19%)

Query: 124  GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGA-AEETRDSDLSELSDTDPL 182
            GA G  G AG P    +  + G       +   G P + G   +E RD            
Sbjct: 1204 GADGIAGAAGPP---GIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDG----------- 1249

Query: 183  SEPDPPARDAASPHQDGAPG-PGPRGGRGQ---EWRPAPGPAPGQGAEASAQGRAEEEGL 238
             +P PP      P + G PG PGP G RG    +       APG   E+ A G   +EGL
Sbjct: 1250 -KPGPPGE----PGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGL 1304

Query: 239  PAK 241
            P K
Sbjct: 1305 PGK 1307



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 37/139 (26%), Positives = 47/139 (33%), Gaps = 18/139 (12%)

Query: 124  GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEET----------RDSDL 173
            G  G  G AG P       A G         D G P  RG +             +D D 
Sbjct: 1252 GPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDT 1311

Query: 174  SELSDTDPLSEPDPPARDAASPHQDGAPGP----GPRGGRGQEWRPAPGPAPGQGAEASA 229
                   P     PP ++  SP   G PGP    G +G +G+   P     PG       
Sbjct: 1312 GPTGPQGPQGPRGPPGKNG-SPGSPGEPGPSGTPGQKGSKGENGSPG---LPGFLGPRGP 1367

Query: 230  QGRAEEEGLPAKAHADGEP 248
             G   E+G+P K    G+P
Sbjct: 1368 PGEPGEKGVPGKEGVPGKP 1386



 Score = 38.1 bits (87), Expect = 0.035
 Identities = 50/222 (22%), Positives = 70/222 (31%), Gaps = 54/222 (24%)

Query: 119  HQCDAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGA----------AEET 168
            + C  G  G  G  G   +  V    G    +  + + G P L G            E  
Sbjct: 1115 NDCPPGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERG 1174

Query: 169  RDSDLSELSDTD---------PLSEPDPPARDA-----------ASPHQDGAPGP----- 203
             D ++ +  D           P   P PP  D             SP ++G PGP     
Sbjct: 1175 ADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSG 1234

Query: 204  -----GPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPAKAHADGEPKAGVRRRRKG 258
                 G  G  G++ +P P   PG+  E    G     G P      G+  A   R   G
Sbjct: 1235 LPGIPGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESG 1294

Query: 259  V----GRHWVPEARASVLRSIQDPWQGPLVQEAPADGMKGPP 296
                 G+  +P          +D   GP   + P  G +GPP
Sbjct: 1295 AMGLPGQEGLPG---------KDGDTGPTGPQGP-QGPRGPP 1326



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 33/127 (25%), Positives = 42/127 (33%), Gaps = 28/127 (22%)

Query: 124  GAGGRRGGAGAPREWNVAYALGSATGDDD--------EDDGGGPRLRGAAEETRDSDLSE 175
            G  G RG  G P       A G   G ++        + D G P + G+     D  +  
Sbjct: 987  GEPGLRGSPGLPGPLGTKAACGKVRGSENCALGGQCVKGDRGAPGIPGSPGSRGDPGIGV 1046

Query: 176  LSDTDPLSEPDPPARDAASPHQDGAPG-PGPRGGRGQEWRPAPGPAPGQGAEASAQGRAE 234
                 P   P     D  SP   G PG PGP+G  G++  P               G   
Sbjct: 1047 AGPPGPSGPPG----DKGSPGSRGLPGFPGPQGPAGRDGAP---------------GNPG 1087

Query: 235  EEGLPAK 241
            E G P K
Sbjct: 1088 ERGPPGK 1094



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 38/145 (26%), Positives = 50/145 (34%), Gaps = 23/145 (15%)

Query: 119  HQCDAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSD 178
            H  D+GA G RG +GA         L    G   +D   GP      +  R       S 
Sbjct: 1280 HTGDSGAPGPRGESGA-------MGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSP 1332

Query: 179  TDPLSEPDPPARDA--ASPHQDGAPG-------------PGPRGGRGQEWRPAPGPAPGQ 223
              P  EP P        S  ++G+PG             PG +G  G+E  P     PG 
Sbjct: 1333 GSP-GEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGF 1391

Query: 224  GAEASAQGRAEEEGLPAKAHADGEP 248
              E    G   ++G P      G+P
Sbjct: 1392 KGERGDPGIKGDKGPPGGKGQPGDP 1416



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 33/115 (28%), Positives = 45/115 (39%), Gaps = 8/115 (6%)

Query: 187  PPARDAASPHQDGAPGP-GPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPAKAHAD 245
            PPA   +S    G PGP GP G  G   R  P   PG+  +   +G +   G   +  A 
Sbjct: 1488 PPAYMKSS---QGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAK 1544

Query: 246  GEPKAGVRRRRKGVGRHWVP--EARASVLRSIQDPWQGPLVQEAPA--DGMKGPP 296
            G+P A     R  +G   +P         +       GP  +  PA   G+ GPP
Sbjct: 1545 GDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPP 1599



 Score = 31.2 bits (69), Expect = 4.2
 Identities = 31/109 (28%), Positives = 40/109 (36%), Gaps = 18/109 (16%)

Query: 156 GGGPRLRGAAEETRDSDLSELSDTDPLSEPDPPARDAASPHQDGAPGP----GPRGGRGQ 211
           GG P L G        ++       P     PP +D      +G PGP    G  G RG+
Sbjct: 728 GGSPGLPG--------EIGFPGKPGPPGPTGPPGKDG----PNGPPGPPGTKGEPGERGE 775

Query: 212 EWRPAPGPAPGQGAEASAQGRAEEEGLPAKAHADGEPKAGVRRRRKGVG 260
           +  P      G+  E    GR  E+G      A G P  GVR  +   G
Sbjct: 776 DGLPGKPGLRGEIGEQGLAGRPGEKGEAGLPGAPGFP--GVRGEKGDQG 822



 Score = 30.0 bits (66), Expect = 9.4
 Identities = 53/195 (27%), Positives = 58/195 (29%), Gaps = 30/195 (15%)

Query: 124 GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLS 183
           G  G RG  G   E       G      D    G P   G A         E  D  P  
Sbjct: 587 GLQGERGEKGTRGEKGERGLDGFPGKPGDTGQQGRPGPSGVA-----GPQGEKGDVGPAG 641

Query: 184 EPDPPA-----------RDAASPH-QDGAPGP-GPRGGRGQEWRPAPGPAPGQGAEASAQ 230
            P  P            + A  P    GAPGP G RG  G E R  P   PG       +
Sbjct: 642 PPGVPGSVVQQEGLKGEQGAPGPRGHQGAPGPPGARGPIGPEGRDGP---PGLQGLRGKK 698

Query: 231 GRAEEEGLPAKAHADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDPWQ-GPLVQEAP- 288
           G     G+P      G P         GV     P     +   I  P + GP     P 
Sbjct: 699 GDMGPPGIPGLLGLQGPPGP------PGVPGPPGPGGSPGLPGEIGFPGKPGPPGPTGPP 752

Query: 289 -ADGMKGPPSGRATK 302
             DG  GPP    TK
Sbjct: 753 GKDGPNGPPGPPGTK 767



 Score = 30.0 bits (66), Expect = 9.4
 Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 12/73 (16%)

Query: 181  PLSEPDPPARDAASPHQDGAPGP-GPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLP 239
            P+ EP  P +       +G  GP GP+G RG +  P    APG G     +G     G+P
Sbjct: 1516 PMGEPGRPGQGGL----EGPSGPIGPKGERGAKGDPG---APGVG----LRGEMGPPGIP 1564

Query: 240  AKAHADGEPKAGV 252
             +    G  K G+
Sbjct: 1565 GQPGEPGYAKDGL 1577


>gi|67188550 CTD (carboxy-terminal domain, RNA polymerase II,
           polypeptide A) phosphatase, subunit 1 isoform FCP1b
           [Homo sapiens]
          Length = 867

 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 52/211 (24%), Positives = 78/211 (36%), Gaps = 36/211 (17%)

Query: 161 LRGAAEETRDSDLSELSDTDPLSEPD-----PPARDAASPHQDGAPGPGPRGGRGQEWRP 215
           L   A E   S+ +   D+    +PD     PPA+ A +  Q+ A  P P+G   Q  R 
Sbjct: 377 LEKPARELNGSEAATPRDSPRPGKPDERDIWPPAQ-APTSSQELAGAPEPQGSCAQGGRV 435

Query: 216 APGPAPGQGA---------EASAQGRAEEEGLPAKAHADGEPKAGVRRRRK--------- 257
           APG  P QGA          + ++  +E EG  + + A      G R R+K         
Sbjct: 436 APGQRPAQGATGTDLDFDLSSDSESSSESEGTKSSSSASDGESEGKRGRQKPKAAPEGAG 495

Query: 258 --------GVGRHWVPEARASVLRSIQDPWQGPLV---QEAPADGMKGPPSGRA-TKTLE 305
                     GR   P            P + P +   +E   DG+ G  +G A  K  E
Sbjct: 496 ALAQGSSLEPGRPAAPSLPGEAEPGAHAPDKEPELGGQEEGERDGLCGLGNGCADRKEAE 555

Query: 306 SRPLGETLRGFCTSEDSDINITSGEEDHKEQ 336
           +      L G    E  D ++   EE+  ++
Sbjct: 556 TESQNSELSGVTAGESLDQSMEEEEEEDTDE 586


>gi|67188445 CTD (carboxy-terminal domain, RNA polymerase II,
           polypeptide A) phosphatase, subunit 1 isoform FCP1a
           [Homo sapiens]
          Length = 961

 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 52/211 (24%), Positives = 78/211 (36%), Gaps = 36/211 (17%)

Query: 161 LRGAAEETRDSDLSELSDTDPLSEPD-----PPARDAASPHQDGAPGPGPRGGRGQEWRP 215
           L   A E   S+ +   D+    +PD     PPA+ A +  Q+ A  P P+G   Q  R 
Sbjct: 377 LEKPARELNGSEAATPRDSPRPGKPDERDIWPPAQ-APTSSQELAGAPEPQGSCAQGGRV 435

Query: 216 APGPAPGQGA---------EASAQGRAEEEGLPAKAHADGEPKAGVRRRRK--------- 257
           APG  P QGA          + ++  +E EG  + + A      G R R+K         
Sbjct: 436 APGQRPAQGATGTDLDFDLSSDSESSSESEGTKSSSSASDGESEGKRGRQKPKAAPEGAG 495

Query: 258 --------GVGRHWVPEARASVLRSIQDPWQGPLV---QEAPADGMKGPPSGRA-TKTLE 305
                     GR   P            P + P +   +E   DG+ G  +G A  K  E
Sbjct: 496 ALAQGSSLEPGRPAAPSLPGEAEPGAHAPDKEPELGGQEEGERDGLCGLGNGCADRKEAE 555

Query: 306 SRPLGETLRGFCTSEDSDINITSGEEDHKEQ 336
           +      L G    E  D ++   EE+  ++
Sbjct: 556 TESQNSELSGVTAGESLDQSMEEEEEEDTDE 586


>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
          Length = 1073

 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 51/190 (26%), Positives = 66/190 (34%), Gaps = 20/190 (10%)

Query: 122 DAGAGGRRGGAGAPREWNVAYALGSATGDDD-EDDGGGPRLRGAAEETRDSDLSELSDTD 180
           + G  G  G  G P   ++        G+   + + G P L G  E        EL    
Sbjct: 320 EKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPG--EPGLQGRPGELGPQG 377

Query: 181 PLSEPDPPARDAA-----SPHQDGAPG----PGPRGGRGQEWRPAPGPAPGQGAEASAQG 231
           P   P    ++ A     +    GAPG    PGP G  G    P     PG+  E   +G
Sbjct: 378 PTGPPGAKGQEGAHGAPGAAGNPGAPGHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEKG 437

Query: 232 RAEEEGLPAKAHADGEPKAGVRRRRKGVGRHWVPEARASVLRSIQDPWQGPLVQEAP--A 289
            A EEG P      G+P A       G G+   P  R S          GPL  +    A
Sbjct: 438 AAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEPGLRGS------PGLPGPLGTKGDRGA 491

Query: 290 DGMKGPPSGR 299
            G+ G P  R
Sbjct: 492 PGIPGSPGSR 501



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 36/131 (27%), Positives = 49/131 (37%), Gaps = 16/131 (12%)

Query: 124 GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLS 183
           GA G  G  GAP        +G+          G P LRG     +D +  E        
Sbjct: 392 GAPGAAGNPGAPGH------VGAPGPSGPPGSVGAPGLRGTPG--KDGERGEKGAAGEEG 443

Query: 184 EPDP--PARDAASPHQDGAPGPGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPAK 241
            P P  P  D  +P   G PGP    G+G++  P    +PG       +G     G+P  
Sbjct: 444 SPGPVGPRGDPGAP---GLPGP---PGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIPGS 497

Query: 242 AHADGEPKAGV 252
             + G+P  GV
Sbjct: 498 PGSRGDPGIGV 508



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 38/123 (30%), Positives = 48/123 (39%), Gaps = 24/123 (19%)

Query: 124 GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGA-AEETRDSDLSELSDTDPL 182
           GA G  G AG P    +  + G       +   G P + G   +E RD            
Sbjct: 651 GADGIAGAAGPP---GIQGSPGKEGPPGPQGPSGLPGIPGEEGKEGRDG----------- 696

Query: 183 SEPDPPARDAASPHQDGAPG-PGPRGGRGQ---EWRPAPGPAPGQGAEASAQGRAEEEGL 238
            +P PP      P + G PG PGP G RG    +       APG   E+ A G   +EGL
Sbjct: 697 -KPGPPGE----PGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGL 751

Query: 239 PAK 241
           P K
Sbjct: 752 PGK 754



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 37/139 (26%), Positives = 47/139 (33%), Gaps = 18/139 (12%)

Query: 124 GAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEET----------RDSDL 173
           G  G  G AG P       A G         D G P  RG +             +D D 
Sbjct: 699 GPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDT 758

Query: 174 SELSDTDPLSEPDPPARDAASPHQDGAPGP----GPRGGRGQEWRPAPGPAPGQGAEASA 229
                  P     PP ++  SP   G PGP    G +G +G+   P     PG       
Sbjct: 759 GPTGPQGPQGPRGPPGKNG-SPGSPGEPGPSGTPGQKGSKGENGSPG---LPGFLGPRGP 814

Query: 230 QGRAEEEGLPAKAHADGEP 248
            G   E+G+P K    G+P
Sbjct: 815 PGEPGEKGVPGKEGVPGKP 833



 Score = 39.3 bits (90), Expect = 0.016
 Identities = 72/338 (21%), Positives = 102/338 (30%), Gaps = 86/338 (25%)

Query: 3   GRPAPVSRKQRLMAAVGERAAGGAPLSCFICGGGIGRGKELKLQVKQPAAGAGTPAQPFF 62
           G P P+  K       G+R A G P       G  G   +  + V  P   +G P     
Sbjct: 478 GLPGPLGTK-------GDRGAPGIP-------GSPGSRGDPGIGVAGPPGPSGPPGDKGS 523

Query: 63  PFLQQQEPAPGARELSPADGCVLVCAVCRCFLGEQWAAFERARTPVDKRMYWLKRPHQCD 122
           P  +     PG +  +  DG                       +P D  +      + C 
Sbjct: 524 PGSRGLPGFPGPQGPAGRDG------------------LSSLLSPGDINLLAKDVCNDCP 565

Query: 123 AGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGA----------AEETRDSD 172
            G  G  G  G   +  V    G    +  + + G P L G            E   D +
Sbjct: 566 PGPPGLPGLPGFKGDKGVPGKPGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGE 625

Query: 173 LSELSDTD---------PLSEPDPPARDA-----------ASPHQDGAPGP--------- 203
           + +  D           P   P PP  D             SP ++G PGP         
Sbjct: 626 VGQKGDQGHPGVPGFMGPPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGI 685

Query: 204 -GPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPAKAHADGEPKAGVRRRRKGV--- 259
            G  G  G++ +P P   PG+  E    G     G P      G+  A   R   G    
Sbjct: 686 PGEEGKEGRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGL 745

Query: 260 -GRHWVPEARASVLRSIQDPWQGPLVQEAPADGMKGPP 296
            G+  +P          +D   GP   + P  G +GPP
Sbjct: 746 PGQEGLPG---------KDGDTGPTGPQGP-QGPRGPP 773



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 38/145 (26%), Positives = 50/145 (34%), Gaps = 23/145 (15%)

Query: 119 HQCDAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSD 178
           H  D+GA G RG +GA         L    G   +D   GP      +  R       S 
Sbjct: 727 HTGDSGAPGPRGESGA-------MGLPGQEGLPGKDGDTGPTGPQGPQGPRGPPGKNGSP 779

Query: 179 TDPLSEPDPPARDA--ASPHQDGAPG-------------PGPRGGRGQEWRPAPGPAPGQ 223
             P  EP P        S  ++G+PG             PG +G  G+E  P     PG 
Sbjct: 780 GSP-GEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPGEKGVPGKEGVPGKPGEPGF 838

Query: 224 GAEASAQGRAEEEGLPAKAHADGEP 248
             E    G   ++G P      G+P
Sbjct: 839 KGERGDPGIKGDKGPPGGKGQPGDP 863



 Score = 33.1 bits (74), Expect = 1.1
 Identities = 33/115 (28%), Positives = 45/115 (39%), Gaps = 8/115 (6%)

Query: 187  PPARDAASPHQDGAPGP-GPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPAKAHAD 245
            PPA   +S    G PGP GP G  G   R  P   PG+  +   +G +   G   +  A 
Sbjct: 935  PPAYMKSS---QGRPGPPGPPGKDGLPGRAGPMGEPGRPGQGGLEGPSGPIGPKGERGAK 991

Query: 246  GEPKAGVRRRRKGVGRHWVP--EARASVLRSIQDPWQGPLVQEAPA--DGMKGPP 296
            G+P A     R  +G   +P         +       GP  +  PA   G+ GPP
Sbjct: 992  GDPGAPGVGLRGEMGPPGIPGQPGEPGYAKDGLPGIPGPQGETGPAGHPGLPGPP 1046



 Score = 30.0 bits (66), Expect = 9.4
 Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 12/73 (16%)

Query: 181  PLSEPDPPARDAASPHQDGAPGP-GPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLP 239
            P+ EP  P +       +G  GP GP+G RG +  P    APG G     +G     G+P
Sbjct: 963  PMGEPGRPGQGGL----EGPSGPIGPKGERGAKGDPG---APGVG----LRGEMGPPGIP 1011

Query: 240  AKAHADGEPKAGV 252
             +    G  K G+
Sbjct: 1012 GQPGEPGYAKDGL 1024


>gi|87196339 collagen, type VI, alpha 1 precursor [Homo sapiens]
          Length = 1028

 Score = 43.5 bits (101), Expect = 8e-04
 Identities = 38/122 (31%), Positives = 43/122 (35%), Gaps = 25/122 (20%)

Query: 122 DAGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDP 181
           D GA G +G  G P     A   GS+    DE   G P   G   E              
Sbjct: 363 DPGAFGLKGEKGEPGADGEAGRPGSSGPSGDEGQPGEPGPPGEKGE-------------- 408

Query: 182 LSEPDPPARDAASPHQDGAPG----PGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEG 237
                  A D  +P  DGAPG    PG RG RG      P   PG+      QGR    G
Sbjct: 409 -------AGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGPQGDQGREGPVG 461

Query: 238 LP 239
           +P
Sbjct: 462 VP 463



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 22/59 (37%), Positives = 28/59 (47%), Gaps = 3/59 (5%)

Query: 191 DAASPHQDGAPG-PGPRGGRGQEWRPA-PGPAPGQGAEASAQGRAEEEGLPAKAHADGE 247
           +   P  DG  G PG  G  G E +P  PGP PG+  EA  +G    +G P +    GE
Sbjct: 372 EKGEPGADGEAGRPGSSGPSGDEGQPGEPGP-PGEKGEAGDEGNPGPDGAPGERGGPGE 429



 Score = 36.2 bits (82), Expect = 0.13
 Identities = 43/138 (31%), Positives = 51/138 (36%), Gaps = 18/138 (13%)

Query: 123 AGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRG--AAEETRD--SDLSELSD 178
           +G  G+ G  G P E   A   G+   D    + GGP  RG      TR    D  E   
Sbjct: 391 SGDEGQPGEPGPPGEKGEAGDEGNPGPDGAPGERGGPGERGPRGTPGTRGPRGDPGEAGP 450

Query: 179 TDPLSEPDPPARDAASPHQDGAPGP-GPRGGRGQEWRP-------APGPAPGQGAEASAQ 230
                   P       P   G  GP GP+G RG E  P       APGPA G   +    
Sbjct: 451 QGDQGREGP----VGVPGDPGEAGPIGPKGYRGDEGPPGSEGARGAPGPA-GPPGDPGLM 505

Query: 231 GRAEEEGLPAKAHADGEP 248
           G   E+G PA    +G P
Sbjct: 506 GERGEDG-PAGNGTEGFP 522


>gi|4758876 poly(A) binding protein, nuclear 1 [Homo sapiens]
          Length = 306

 Score = 43.1 bits (100), Expect = 0.001
 Identities = 40/109 (36%), Positives = 48/109 (44%), Gaps = 17/109 (15%)

Query: 125 AGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPLSE 184
           AGGR  G G  R     + +  A G+  E   GG    G   E+ + +  EL   +P  E
Sbjct: 14  AGGRGSGPGRRR-----HLVPGAGGEAGEGAPGGAGDYGNGLESEELEPEELL-LEPEPE 67

Query: 185 PDP---PARDAASPHQDGAPGPGPRGGR--GQEWRPAPGPA---PGQGA 225
           P+P   P R  A P   GAPGPGP  G    QE    PG     PG GA
Sbjct: 68  PEPEEEPPRPRAPP---GAPGPGPGSGAPGSQEEEEEPGLVEGDPGDGA 113



 Score = 37.4 bits (85), Expect = 0.059
 Identities = 37/123 (30%), Positives = 46/123 (37%), Gaps = 25/123 (20%)

Query: 123 AGAGGRRGGAGAPREWNVAYALGSATGDDDEDDGGGPRLRGAAEETRDSDLSELSDTDPL 182
           AGA G RG +G  R  ++    G   G+      G P   GA +     +  EL   + L
Sbjct: 11  AGAAGGRG-SGPGRRRHLVPGAGGEAGE------GAPG--GAGDYGNGLESEELEPEELL 61

Query: 183 SEPDPPARDAASPHQDGAPGPGPRGGRGQEWRPAPGPAPGQGAEASAQGRAEEEGLPAKA 242
            EP+P       P       P PR         AP  APG G  + A G  EEE  P   
Sbjct: 62  LEPEPEPEPEEEP-------PRPR---------APPGAPGPGPGSGAPGSQEEEEEPGLV 105

Query: 243 HAD 245
             D
Sbjct: 106 EGD 108


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.434 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,105,350
Number of Sequences: 37866
Number of extensions: 2562393
Number of successful extensions: 17288
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 150
Number of HSP's successfully gapped in prelim test: 595
Number of HSP's that attempted gapping in prelim test: 11608
Number of HSP's gapped (non-prelim): 3679
length of query: 847
length of database: 18,247,518
effective HSP length: 111
effective length of query: 736
effective length of database: 14,044,392
effective search space: 10336672512
effective search space used: 10336672512
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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